QUERY_TERM PMID JOURNAL_TITLE YEAR PMCID DOI PMC_CITATION_COUNT INDRA_STATEMENT_COUNT OC_CITATION_COUNT INDRA_QUERY_TERM_STATEMENT_COUNT MESH_TERMS PMID_COUNT 194223 32635161 Genes (Basel) 2020 10.3390/genes11070740 0 0 0 0 Animals|*Gene Knockout Techniques|*Zebrafish|Genome Editing|Clustered Regularly Interspaced Short Palindromic Repeats|CRISPR-Cas Systems|RNA, Guide|Endonucleases|Mutagenesis|*DNA|Mutation 402 194223 32630105 Int J Mol Sci 2020 10.3390/ijms21134680 0 0 0 0 Male|*Insulin Resistance|*Lipoprotein(a)|Body Mass Index|Sleep|Apo B|Apolipoprotein AI|APOB protein, human|Apolipoprotein B-100|Hypertension|Risk Factors|Diabetes Mellitus|Lifestyle 402 194223 32619531 BioSystems 2020 10.1016/j.biosystems.2020.104192 0 0 0 0 Animals|*Drosophila|*Gene Regulatory Networks|Drosophila Proteins|Drosophila melanogaster|Transcription Factors|Body Patterning|*Neural Stem Cells|*Embryonic Development|Homeodomain Proteins|Gene Expression Regulation, Developmental|Kruppel-Like Transcription Factors|Genetic Evolution|hunchback protein, Drosophila|kni protein, Drosophila|Repressor Proteins 402 194223 32593254 Adv Gerontol 2020 0 0 0 0 Male|Mice|Animals|cytoflavin|*Inosine Diphosphate|*Flavin Mononucleotide|*Succinates|*Niacinamide|*Drug Combinations|*Aging|ERBB2 protein, human|Receptor, ErbB-2|Mice, Transgenic|Apoptosis|Sensorimotor Cortex 402 194223 32566783 Heliyon 2020 PMC7298408 10.1016/j.heliyon.2020.e04146 0 0 0 0 Animals|*Retina|*Fovea Centralis|*Microscopy, Electron|Intermediate Filaments|Songbirds 402 194223 32562696 Biochim Biophys Acta Biomembr 2020 10.1016/j.bbamem.2020.183401 0 0 0 0 Animals|*Potassium Channels|*Glutamate|*Ion Channels|Ion Channel Gating|*Biophysical Phenomena|Amino Acid Sequence|Xenopus laevis 402 194223 32531067 Hum. Reprod. 2020 10.1093/humrep/deaa097 0 0 0 0 Humans|Female|*Granulosa Cells|*Oocytes|*Autophagy|*Phagocytosis 402 194223 32485234 Mol. Cell. Probes 2020 10.1016/j.mcp.2020.101611 0 0 0 0 Animals|Rats|*Real-Time Polymerase Chain Reaction|*Rats, Wistar|*Gene Expression|Reference Standards|House-keeping Genes|Gene Expression Profiling|*Biological Assay 402 194223 32483756 Dokl. Biochem. Biophys. 2020 10.1134/S1607672920020064 0 0 0 0 Animals|Rats|*Thyroid Stimulating Hormone|Thyroid Stimulating Hormone Receptor|Gland, Thyroid|Graves Disease|Thyroliberin|Hyperthyroidism|Adenylyl Cyclases|Receptors, G-Protein-Coupled|Cell Membrane|pyrimidine|Pyrimidines|*Drug Hypersensitivity 402 194223 32477601 Acta Naturae 2020 PMC7245957 10.32607/actanaturae.10943 0 0 0 0 Rats|Animals|vasotocin receptor|Vasopressin Receptors|arginine vasopressin receptor 2, human|AVP protein, human|Vasopressin|Vasotocin|Sodium|Receptors, Oxytocin|Potassium|Pituitary Hormones, Posterior|mesotocin|Oxytocin|Vertebrates|Kidney|Neurophysins 402 194223 32455746 Brain Sci 2020 PMC7288135 10.3390/brainsci10050311 0 0 0 0 Animals|Rats|*Epilepsy, Reflex|*Rats, Wistar|Glycogen Synthase Kinase 3|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Mitogen-Activated Protein Kinase 1|gamma-Aminobutyric Acid|Synapsins|Vesicular Glutamate Transport Protein 2|*Neural Stem Cells|Synaptosomal-Associated Protein 25|Acoustic Stimulation|Hippocampus|Neurons 402 194223 32450204 Insect Biochem. Mol. Biol. 2020 10.1016/j.ibmb.2020.103411 0 0 0 0 Animals|*Pyrethroids|*Aedes|Insecticide Resistance|Insecticides|Voltage-Gated Sodium Channels|*Mutations|Insect Proteins 402 194223 32362087 Adv Gerontol 2020 0 0 0 0 Aged|Male|Female|Humans|Adolescent|Young Adult|Adult|Middle Aged|Aged, 80 and over|*Autonomic Nervous System|*Cardiovascular System|Heart Rate|Blood Pressure|Aging|Catecholamines 402 194223 32362081 Adv Gerontol 2020 0 0 0 0 Mice|Female|Animals|Phosphatidylinositol 3-Kinases|CASP8 protein, human|Caspase-8|*Apoptosis|fas Receptor|FASLG protein, human|Fas Ligand Protein|TUNEL|Caspases|TNF Receptor-Associated Death Domain Protein|ERBB2 protein, human|Receptor, ErbB-2|Adaptor Proteins, Signal Transducing|Signal Transduction|*Aging|Carrier Proteins 402 194223 32357511 Pharmaceuticals (Basel) 2020 PMC7281561 10.3390/ph13050080 0 0 0 0 Animals|Rats|*Pentylenetetrazole|*Anticonvulsants|*Cefepime|*Seizures|Electroshock|GABA A Receptor|Synaptic Transmission|Cephalosporins|Dose-Response Relationship, Drug 402 194223 32259924 Rev Sci Instrum 2020 10.1063/1.5129863 0 0 0 0 *Diamond|*Microwaves|*Nitrogen|Magnetic Field|Computer Simulation|Equipment Design 402 194223 32244116 Ecotoxicol. Environ. Saf. 2020 10.1016/j.ecoenv.2020.110519 0 0 0 0 Rats|Animals|paxilline|*Cadmium|Mitochondria, Liver|*Indoles|Mitochondria|Membrane Potential, Mitochondrial|Reactive Oxygen Species|Cell Respiration|Electron Transport|Hepatoma|Viability, Cell|Liver Neoplasms|Environmental Pollutants|Cell Line, Tumor 402 194223 32237809 J. Acoust. Soc. Am. 2020 10.1121/10.0000909 0 0 0 0 Animals|*Bottle-Nosed Dolphin|Noise|Auditory Threshold|Perceptual Masking|Hearing|Acoustic Stimulation|Auditory Evoked Potential|Hearing Tests 402 194223 32197321 Pharmaceuticals (Basel) 2020 PMC7151710 10.3390/ph13030048 0 0 0 0 Rats|Animals|*Lipopolysaccharides|Long-Term Potentiation|*Synaptic Plasticity|metabotropic glutamate receptor type 1|Receptors, Metabotropic Glutamate|N Methyl D Aspartate Receptors|Hippocampus|Synaptic Transmission|CA1 Region, Hippocampal|N Methyl D aspartate|Synapses 402 194223 32162136 Histochem. Cell Biol. 2020 10.1007/s00418-020-01851-3 0 0 0 0 Rats|Animals|*Enterocytes|Golgi Complex|Endoplasmic Reticulum|Biological Transport|*Transcytosis|*Lipids 402 1.2.7.1 32658264 J. Clin. Endocrinol. Metab. 2020 10.1210/clinem/dgaa450 0 0 0 0 Female|Humans|PTHLH protein, human|abaloparatide|*Parathyroid Hormone-Related Protein|*Postmenopause|*Osteoporosis|Osteoporosis, Postmenopausal|Teriparatide|Bone Density Conservation Agents|Osteoporotic Fractures|Bone Density|Spinal Fractures|Lumbar Vertebrae 429 1.2.7.1 32381582 Clin J Am Soc Nephrol 2020 PMC7274281 10.2215/CJN.12541019 0 0 0 0 Humans|*Kidney Transplantation|*Races|*Socioeconomic Status|Healthcare Disparities|Health Status Disparities|African Americans|*Comorbidity|Socioeconomic Factors|Kidney Failure, Chronic 429 1.2.7.1 32019152 Animals (Basel) 2020 PMC7070707 10.3390/ani10020223 0 0 0 0 429 1.2.7.1 31978429 Chest 2020 10.1016/j.chest.2019.12.023 0 0 0 0 *Corticosteroids|Anti-Asthmatic Agents|Administration, Inhalation|Asthma|Muscarinic Antagonists|*Tracheobronchomalacia|Drug Therapy, Combination 429 1.2.7.1 31922481 Turk J Urol 2020 PMC7053981 10.5152/tud.2019.19147 0 0 0 0 Child|Female|Humans|*Nocturia|*Nocturnal Enuresis|*Mothers|*Urinary Incontinence|Polyuria|Urodynamics|Age Factors 429 1.2.7.1 32658264 J. 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Metab. 2020 10.1210/clinem/dgaa450 0 0 0 0 Female|Humans|PTHLH protein, human|abaloparatide|*Parathyroid Hormone-Related Protein|*Postmenopause|*Osteoporosis|Osteoporosis, Postmenopausal|Teriparatide|Bone Density Conservation Agents|Osteoporotic Fractures|Bone Density|Spinal Fractures|Lumbar Vertebrae 429 1.2.7.1 32381582 Clin J Am Soc Nephrol 2020 PMC7274281 10.2215/CJN.12541019 0 0 0 0 Humans|*Kidney Transplantation|*Races|*Socioeconomic Status|Healthcare Disparities|Health Status Disparities|African Americans|*Comorbidity|Socioeconomic Factors|Kidney Failure, Chronic 429 1.2.7.1 32019152 Animals (Basel) 2020 PMC7070707 10.3390/ani10020223 0 0 0 0 429 1.2.7.1 31978429 Chest 2020 10.1016/j.chest.2019.12.023 0 0 0 0 *Corticosteroids|Anti-Asthmatic Agents|Administration, Inhalation|Asthma|Muscarinic Antagonists|*Tracheobronchomalacia|Drug Therapy, Combination 429 1.2.7.1 31922481 Turk J Urol 2020 PMC7053981 10.5152/tud.2019.19147 0 0 0 0 Child|Female|Humans|*Nocturia|*Nocturnal Enuresis|*Mothers|*Urinary Incontinence|Polyuria|Urodynamics|Age Factors 429 5S_rRNA 32634612 Microb. Pathog. 2020 10.1016/j.micpath.2020.104368 0 0 0 0 3653 5S_rRNA 32591429 Plant Physiol. 2020 10.1104/pp.20.00502 0 0 0 0 3653 5S_rRNA 32589504 Nucleic Acid Ther 2020 10.1089/nat.2020.0864 0 0 0 0 3653 5S_rRNA 32553108 Elife 2020 PMC7326499 10.7554/eLife.59264 0 0 0 0 3653 5S_rRNA 32518240 Nat Commun 2020 PMC7283268 10.1038/s41467-020-16694-8 0 0 0 0 3653 5S_rRNA 32449429 RNA Biol 2020 10.1080/15476286.2020.1771946 0 0 0 0 3653 5S_rRNA 32424559 J. Mol. Med. 2020 PMC7297814 10.1007/s00109-020-01922-x 0 0 0 0 3653 5S_rRNA 32359200 J. 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Genome 2020 10.1007/s00335-020-09838-0 0 0 0 0 Animals|Swine|*RNA, Small Interfering|*RNA Polymerase III|RNAi|*Promoter Regions, Genetic|enhanced green fluorescent protein|Green Fluorescent Proteins|RNA, Small Nuclear|Transfections|Genetic Vectors|Base Sequence|Gene Expression|Genetic Therapy|Cell Line 3653 5S_rRNA 32317317 mBio 2020 PMC7175087 10.1128/mBio.00010-20 0 0 0 0 *Cost-Benefit Analysis|*Sequencing, RNA|*RNA, Ribosomal|mRNA|Gene Expression Profiling|RNA|*Whole Exome Sequencing|*Base Sequence|Bacteria|Nucleic Acid Hybridization 3653 5S_rRNA 32312833 Cancer Res. 2020 10.1158/0008-5472.CAN-19-3326 0 0 0 0 Humans|Mice|Animals|RNA, Long Noncoding|Enhancer of Zeste Homolog 2 Protein|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Carcinoma, Non-Small-Cell Lung|Cell Proliferation|Downregulation|Cell Line, Tumor|Carcinogenesis|Disease Progression|*Genomic Instability|*Ribosome|EZH2 protein, human 3653 5S_rRNA 32306293 J. Mol. Neurosci. 2020 10.1007/s12031-020-01511-0 0 0 0 0 Humans|*Alzheimer Disease|*MicroRNAs|Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Amyloid beta-Peptides|*Biomarkers|Plaque, Amyloid 3653 5S_rRNA 32279660 BMC Biol. 2020 PMC7153239 10.1186/s12915-020-0763-0 0 0 0 0 Humans|*RNA, Ribosomal|Transfer RNA|Non-Coding RNA|RNA, Micro|Sequencing, Next-Generation 3653 5S_rRNA 32275312 J. Exp. Bot. 2020 10.1093/jxb/eraa019 0 0 0 0 3653 5S_rRNA 32273179 Mar Genomics 2020 10.1016/j.margen.2020.100771 0 0 0 0 *Bacillus|16S rRNA|Genome, Bacterial|G+C Content|*Base Sequence|rRNA Operons|DNA, Bacterial|23S rRNA|Sequence Analysis, DNA|Whole Genome Sequencing|Phylogeny|Geologic Sediments|5S rRNA|*Bacteria|China 3653 5S_rRNA 32251374 Nat Plants 2020 10.1038/s41477-020-0631-5 1 0 0 0 3653 5S_rRNA 32163391 Mol. Biol. (Mosk.) 2020 10.31857/S0026898419040165 0 0 0 0 3653 A2ML1 32514133 Eur. J. Hum. Genet. 2020 10.1038/s41431-020-0658-0 0 0 0 58 39 A2ML1 32439251 J. Dermatol. Sci. 2020 10.1016/j.jdermsci.2020.04.005 0 0 0 58 39 A2ML1 32391049 Front Genet 2020 PMC7191070 10.3389/fgene.2020.00313 0 0 0 58 Humans|Mice|Animals|*Otitis Media|Genetic Predisposition to Disease|*Genomics|Chronic Disease|Hearing Impairment 39 A2ML1 32198464 Sci Rep 2020 PMC7083932 10.1038/s41598-020-61714-8 1 0 0 58 Pregnancy|Female|Animals|Humans|*Callithrix|*Pregnancy Proteins|*Proteins|Placenta|Amino Acid Sequence|alpha-Macroglobulins|A2ML1 protein, human 39 A2ML1 32117425 Front Genet 2020 PMC7025460 10.3389/fgene.2019.01395 0 0 0 58 Humans|Mice|Animals|*Otitis Media|Middle Ear|Genetic Predisposition|Eustachian Tube|Immunity|Disease Models, Animal 39 A2ML1 32048534 Epigenomics 2020 10.2217/epi-2019-0374 0 0 0 58 39 A2ML1 31998560 PeerJ 2020 PMC6979404 10.7717/peerj.8403 0 0 0 58 39 A2ML1 31921195 Front Immunol 2020 PMC6930242 10.3389/fimmu.2019.02948 1 0 0 58 39 A4GALT 32617522 FASEB Bioadv 2020 PMC7325589 10.1096/fba.2019-00080 0 0 0 57 Mice|Animals|*Hyperparathyroidism, Secondary|Parathyroid Hormone|*Osteopenia|Vitamin D Deficiency|Osteoporosis|Kidney Failure, Chronic|Phosphates|Fabry Disease 44 A4GALT 32523894 Front Cell Infect Microbiol 2020 PMC7261856 10.3389/fcimb.2020.00212 0 0 0 57 44 A4GALT 32507026 Virulence 2020 10.1080/21505594.2020.1773077 0 0 0 57 44 A4GALT 32355479 Transfus Med Hemother 2020 PMC7184825 10.1159/000501916 0 0 0 57 44 A4GALT 32179651 J. 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Biol. 2020 10.1016/j.jmb.2020.04.018 0 0 0 0 Rats|Humans|Animals|*Signal Transduction|Receptor, trkA|PC12 Cells|Optogenetics 682 Activation of TRKA receptors 32323951 Zh Nevrol Psikhiatr Im S S Korsakova 2020 10.17116/jnevro202012003197 0 0 0 0 Child|Humans|*Autistic Disorder|Synapses|Long-Term Synaptic Depression|Long-Term Potentiation|Synaptic Transmission|Receptors, Metabotropic Glutamate|Hippocampus|Excitatory Amino Acid Antagonists 682 Activation of TRKA receptors 32319659 Oncol. Rep. 2020 10.3892/or.2020.7583 0 0 0 0 *Neuroblastomas|Receptor, trkA|Receptors, Neurotrophin|Glial Cell Line-Derived Neurotrophic Factor Receptors|Cell Differentiation|*Carrier Proteins|Phosphorylation|Proto-Oncogene Proteins c-ret|Signal Transduction|Nerve Growth Factor|Glial Cell Line-Derived Neurotrophic Factor|Cell Proliferation 682 Activation of TRKA receptors 32316846 Lupus 2020 10.1177/0961203320919489 0 0 0 0 Humans|NGF protein, human|*Nerve Growth Factor|Receptor, trkA|Receptor, Nerve Growth Factor|Receptors, Nerve Growth Factor|*Lupus Erythematosus, Systemic|*Leukocytes|Dendritic Cells 682 Activation of TRKA receptors 32281946 J. Clin. Invest. 2020 PMC7190980 10.1172/JCI130401 1 0 0 0 Humans|Animals|*Dysautonomia, Familial|Neurons|*Signal Transduction|Cell Survival|Cell Death|trkA Receptor|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Nervous System, Sympathetic|Disease Models, Animal|Nerve Growth Factors 682 Activation of TRKA receptors 32198666 Glycoconj. J. 2020 10.1007/s10719-020-09919-x 1 0 0 0 Mice|Animals|*Gangliosides|G(M1)-oligosaccharide|GM1 Ganglioside|*Oligosaccharides|*Neurons|*Cell Differentiation|Receptor, trkA|Signal Transduction|Neuroblastoma|Phosphorylation|Neuroprotection 682 ADAM29 32194665 Oncol Lett 2020 PMC7039107 10.3892/ol.2020.11272 0 0 0 13 *Esophageal Cancer|Esophageal Squamous Cell Carcinoma|*Esophageal Mucosa|Carcinoma, Squamous Cell|Lymphatic Metastasis|Immunohistochemistry|Prognosis|Biomarkers, Tumor|Epithelium|Carcinoma in Situ|Esophagus|Carcinogenesis|Disease Progression|*Metalloproteases 31 ADAMDEC1 32392191 Mol. Biol. (Mosk.) 2020 10.31857/S0026898420020044 0 0 0 24 Humans|*Genetic Predisposition to Disease|Aquaporin 2|*Myocardial Infarction|SNPs|Genotype|Genome-Wide Association Study|Quantitative Trait Loci|Case-Control Studies|Risk Factors|RNA, Long Noncoding|Gene Expression 42 ADAMDEC1 32378728 Histol. Histopathol. 2020 10.14670/HH-18-227 0 0 0 24 Humans|*Glioma|Cell Proliferation|Brain Neoplasms|Apoptosis|Cell Movement|Neoplasm Invasiveness|Cell Cycle|Gene Knockdown Techniques|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Signal Transduction|RNA, Small Interfering|Prognosis|*Disease Progression 42 ADAMDEC1 31993498 Mol Cell Oncol 2020 PMC6961677 10.1080/23723556.2019.1684787 0 0 0 24 *Fibroblast Growth Factor 2|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|*Signal Transduction|*Cancer Stem Cells|Autocrine Communication|Glioblastoma|Cell Proliferation|Cell Line, Tumor 42 ADGRG6 32337710 Br. J. Pharmacol. 2020 PMC7348089 10.1111/bph.15074 1 0 0 122 *Pulmonary Artery|*Pulmonary Arterial Hypertension|*Transcriptome|*Smooth Muscle Cells|*Idiopathic Pulmonary Arterial Hypertension|Hypertension, Pulmonary|Muscle, Smooth, Vascular|*Transcriptome Analysis|Cell Proliferation|Cells, Cultured 42 ADGRG6 32219165 Sci Adv 2020 PMC7083604 10.1126/sciadv.aaz0368 0 0 0 122 Humans|Mice|Animals|*Receptors, G-Protein-Coupled|Schwann Cells|Myelin Sheath|Signal Transduction|*Bone Density|Gpr126 protein, mouse 42 ADGRG6 32203115 Int J Obes (Lond) 2020 10.1038/s41366-020-0570-2 0 0 0 122 Mice|Animals|*Adipocytes|Adipogenesis|3T3-L1 Cells|Adipose Tissue|Lipolysis|*G-Protein-Coupled Receptors|Lipid Metabolism|Cell Differentiation|Obesity 42 ADGRG6 32024818 Nat Commun 2020 PMC7002750 10.1038/s41467-019-13929-1 1 0 0 122 Humans|*Cancers|Genome, Human|Genomics|Mutation|Sequencing, Whole Genome|Computational Biology 42 ADGRG6 31924782 Nat Commun 2020 PMC6954182 10.1038/s41467-019-14040-1 1 0 0 122 Animals|Humans|*G-Protein-Coupled Receptors|Zebrafish|Zebrafish Proteins|Schwann Cells|Myelin Sheath|Signal Transduction|Cyclic AMP 42 AEBP1 32565808 J Oncol 2020 PMC7273425 10.1155/2020/8097872 0 0 0 112 *Signal Transduction|NF-kappa B|*Oncogene|Repressor Proteins|Carboxypeptidases|Macrophage|Inflammation|Atherogenesis|Cholesterol 91 AEBP1 32482891 J. 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Rep. 2020 PMC6967157 10.3892/or.2019.7429 2 0 0 112 Humans|*Urinary Bladder Neoplasms|*Prognosis|*Disease Progression|Gene Expression Profiling|*Risk Factors|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|Genes, Regulator|Cohort Studies|Receiver Operating Characteristic|CTHRC1 protein, human|Extracellular Matrix Proteins 91 AFAP1L2 32159887 Mol. Carcinog. 2020 10.1002/mc.23180 0 0 0 160 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|RNA, Micro|Epithelial-Mesenchymal Transition|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|*Neoplastic Processes|3' Untranslated Regions|Cell Line, Tumor|Adaptor Proteins, Signal Transducing|Cell Cycle|MIRN203 microRNA, human|MIRN219 microRNA, human 30 AFF2 32485067 Hum. Mutat. 2020 10.1002/humu.24058 0 0 0 75 Humans|Female|*X Chromosome Inactivation|Chromosomes, Human, X|Heterozygote|Intellectual Disability|Chromatin|FMR1 protein, human|Fragile X Mental Retardation Protein 108 AFF2 32393163 J Neurodev Disord 2020 PMC7212686 10.1186/s11689-020-09317-2 0 0 0 75 Humans|Male|*Oculocerebrorenal Syndrome|*Induced Pluripotent Stem Cells|*Transcriptome Analysis|*Neural Stem Cells|Phosphoric Monoester Hydrolases|Mutations|Cells, Cultured|Endosomes 108 AFF2 32366754 Am. J. Surg. Pathol. 2020 10.1097/PAS.0000000000001498 0 0 0 75 Humans|Male|Female|Nuclear Proteins|Transcription Factors|*Squamous Cell Carcinomas|Human Papilloma Virus|Immunohistochemistry|Biomarkers, Tumor|*Temporal Bone|*Uterine Cervical Neoplasms|*Middle Ear|Dek protein, human|Poly-ADP-Ribose Binding Proteins|Chromosomal Proteins, Non-Histone|Oncogene Proteins|BRD4 protein, human 108 AFF2 31948430 BMC Cancer 2020 PMC6966810 10.1186/s12885-020-6515-2 1 0 0 75 *RNA, Circular|*Multiple Myeloma|*Prognosis|MicroRNAs|Biomarkers 108 AIF1 32642296 Am J Cancer Res 2020 PMC7339265 0 0 0 1453 Animals|*Thyroid Cancer|Thyroid cancer, follicular|Adenocarcinoma, Follicular|*Cell Proliferation|Thyroid Gland|Thyroid Hormone Receptors beta|*Disease Models, Animal|PTEN Phosphohydrolase|Signal Transduction|*Inflammation 1672 AIF1 32578724 Acta Cir Bras 2020 PMC7307720 10.1590/s0102-865020200040000006 0 0 0 1453 Animals|rosmarinic acid|*Depsides|*Cinnamates|*Brain|Traumatic Brain Injury|Glial Fibrillary Acidic Protein|Neuroprotective Agents|Astrocytes|Disease Models, Animal|*Craniectomy 1672 AIF1 32573635 Food Funct 2020 10.1039/d0fo00741b 0 0 0 1453 1672 AIF1 32434993 JCI Insight 2020 PMC7259535 10.1172/jci.insight.136092 0 0 0 1453 1672 AIF1 32287325 PLoS ONE 2020 PMC7156095 10.1371/journal.pone.0231597 0 0 0 1453 1672 AIF1 32206887 Parasitol. Res. 2020 PMC7263952 10.1007/s00436-020-06645-z 0 0 0 1453 Mice|Animals|*Chagas Disease|Trypanosoma cruzi|Chagas Cardiomyopathy|Myocardium|*Cardiomyopathy|Heart|Mice, Knockout|Parasitemia|Inflammation|Mice, Transgenic|Disease Models, Animal 1672 AIF1 32155215 PLoS ONE 2020 PMC7064230 10.1371/journal.pone.0230080 0 0 0 1453 Male|Humans|Mice|Animals|*Bone Marrow Stromal Stem Cells|*Bone Marrow|*Injury, Spinal Cord|CCL2 protein, human|*Chemokine CCL2|Mesenchymal Stem Cell Transplantation|CCL5 protein, human|*Chemokine CCL5|Nerve Regeneration|Spinal Cord|Macrophages|Recovery of Function|Chemokines|CCR5 protein, human|Receptors, CCR5|Microglia|*Neurogenesis|Inflammation 1672 AIF1 32110485 PeerJ 2020 PMC7032059 10.7717/peerj.8543 0 0 0 1453 Swine|Animals|*Macrophages, Alveolar|Classical Swine Fever|*Macrophage|Classical Swine Fever Virus|*Up-Regulation|*Cells, Alveolar|*Transcriptional Activation|Cell Line|Cells, Cultured|mRNA|Proteins 1672 AIF1 32107417 Sci Rep 2020 PMC7046694 10.1038/s41598-020-60433-4 0 0 0 1453 Humans|Mice|Animals|*Diet, High-Fat|*Glucose|*Gain, Weight|*Obesity|Body Weight|Glucose Intolerance|Adiposity|Energy Expenditure|Body Composition|Muscle, Skeletal|Liver|Disease Models, Animal|Allografts 1672 AIF1 32057593 Eur Neuropsychopharmacol 2020 10.1016/j.euroneuro.2020.01.012 0 0 0 1453 Rats|Animals|*Endocannabinoids|*Alcohol Drinking|Ethanol|Alcohol Use Disorder|Cortex, Prefrontal|Amygdala|Hippocampus|Brain|Gene Expression|Aif1 protein, rat|Calcium-Binding Proteins|Microfilament Proteins 1672 AIF1 32029867 Commun Biol 2020 PMC7005279 10.1038/s42003-020-0780-0 0 0 0 1453 *Cryoelectron Microscopy|Initiation Factors|Sulfolobus solfataricus|RNA, Transfer, Met|Archaeal Proteins|Guanosine Triphosphate|Models, Molecular 1672 AIF1 32014511 Neurotoxicology 2020 PMC7294247 10.1016/j.neuro.2020.01.014 0 0 0 1453 Animals|Mice|*Lipopolysaccharides|Microglia|Astrocytes|Cytokines|TLR4 Receptor|Inflammation|Glial Fibrillary Acidic Protein|Nerve Degeneration|Brain|Neurotoxicity Syndromes|Calcium-Binding Proteins|Hippocampus|*Macrophage Activation|Microfilament Proteins|Signal Transduction|Innate Immune Response 1672 AIF1 32001673 Cell Death Dis 2020 PMC6992638 10.1038/s41419-020-2280-z 1 0 0 1453 1672 AIF1 31963507 Int J Mol Sci 2020 PMC7013601 10.3390/ijms21020612 0 0 0 1453 1672 AIF1 31953431 Sci Rep 2020 PMC6969154 10.1038/s41598-019-57290-1 0 0 0 1453 1672 AIF1 31896310 Toxicol Pathol 2020 PMC7113115 10.1177/0192623319896263 0 0 0 1453 1672 AIF1 31892813 Turk. J. Biol. 2020 PMC6911262 10.3906/biy-1908-11 1 0 0 1453 1672 AJAP1 32528872 Front Oncol 2020 PMC7253684 10.3389/fonc.2020.00667 0 0 0 135 *Down-Regulation|*Urinary Bladder Neoplasms|*Cell Proliferation|5-hydroxymethylcytosine|5 Methylcytosine|DNA Methylation|Dioxygenases|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Proto-Oncogene Proteins|Wnt Signaling Pathway|Mixed Function Oxygenases|Promoter Regions, Genetic|Epithelial-Mesenchymal Transition|Cell Line, Tumor|*Translocation, Genetic|*Neoplastic Processes|DNA 58 AJAP1 32067740 Biochem. Biophys. Res. Commun. 2020 10.1016/j.bbrc.2020.02.036 0 0 0 135 Animals|TYRP1 protein, human|*Membrane Glycoproteins|Epilepsy, Temporal Lobe|*Synapsins|Carrier Proteins|Disease Models, Animal|Junctions, Adherens|gamma-Aminobutyric Acid 58 AJAP1 32030084 Curr. Genomics 2020 PMC6983957 10.2174/1389202920666190730132411 0 0 0 135 Humans|Adolescent|*Scoliosis|*Kyphosis|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genetic Association Studies|Homeodomain Proteins|Transcription Factors|Genotype|Case-Control Studies 58 AKAP4 32460071 Sci. Total Environ. 2020 10.1016/j.scitotenv.2020.139233 0 0 0 1712 Humans|Male|Mice|Animals|*Acrosome|*Sperm Motility|*Arsenic|*Sperm|*Spermiogenesis|Sperm Flagellum|Infertility, Male|Testes|*Flagellum|Fertility|*Proteomics|A Kinase Anchor Proteins|*Protein Processing, Post-Translational 93 AKAP4 32439377 Gene 2020 10.1016/j.gene.2020.144778 0 0 0 1712 Male|Humans|Pregnancy|Female|Animals|Sheep|*Litter Size|*Goats|*Sperm Flagellum|Infertility, Male|Mutations, INDEL|*DNA Mutational Analysis|Cytoskeletal Proteins|Mutation|Genotype|Genetic Association Studies|Phenotype|Reproduction|AKAP4 protein, human|A Kinase Anchor Proteins 93 AKAP4 32342732 Tumour Biol. 2020 10.1177/1010428320914477 0 0 0 1712 Humans|AKAP4 protein, human|*A Kinase Anchor Proteins|*Triple-Negative Breast Cancers|Cellular Proliferation|Cell Line, Tumor|Paclitaxel|Xenograft Model Antitumor Assays|Apoptosis|Cell Cycle|Cell Movement|Antineoplastic Agents|Cell Survival|Gene Knockdown Techniques|Gene Expression Regulation, Neoplastic|Cyclin-Dependent Kinases 93 AKAP4 32249078 J Integr Med 2020 10.1016/j.joim.2020.03.003 0 0 0 1712 Male|*Mucuna|*Antioxidants|Thailand|*Seeds|Phytotherapy|Plant Extracts|Spermatozoa|*Reproduction 93 AKAP4 31969501 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2020 10.11817/j.issn.1672-7347.2019.190546 0 0 0 1712 Humans|Male|Mice|Animals|Sperm Motility|*Sperm Flagellum|Sperm|AKAP4 protein, human|*A Kinase Anchor Proteins|Infertility, Male|Spermatogenesis|Testis|Mice, Knockout|Immunofluorescence|*Cytoskeleton 93 AKAP4 31969357 Development 2020 10.1242/dev.181057 0 0 0 1712 Humans|Male|Mice|Animals|*Proteome|*Sperm|*Male Sterility|Sperm Flagellum|Sperm Motility|A Kinase Anchor Proteins|Spermiogenesis|Sperm Maturation|Cyclic AMP-Dependent Protein Kinases|Proteomics 93 AKAP4 31958312 Reproduction 2020 PMC7187893 10.1530/REP-17-0789 1 0 0 1712 Male|Mice|Animals|*Spermiogenesis|Sperm Tail|Spermatozoa|Flagella|Cilia|Testis|Spermatids|Transport Proteins|Fertility|Intracellular Signaling Peptides and Proteins|*B-Lymphocytes|Protein Transport|Protein Binding|IFT25 protein, mouse 93 AKAP4 31921838 Front Cell Dev Biol 2020 PMC6933317 10.3389/fcell.2019.00319 1 0 0 1712 Humans|Male|Mice|Animals|AKAP4 protein, human|*A Kinase Anchor Proteins|Sperm Motility|Spermatozoa|Spermatids|Sperm Tail|4-hydroxy-2-nonenal|Aldehydes|Lipid Peroxidation|Infertility, Male|Oxidative Stress|Proteolysis 93 AKAP4 31901658 Chemosphere 2020 10.1016/j.chemosphere.2019.125772 0 0 0 1712 Humans|Male|Mice|Animals|*Sperm Tail|*Testis|*Fluorides|Sperm Motility|Sperm|Spermatogenesis|Infertility, Male|AKAP4 protein, human|A Kinase Anchor Proteins|Axoneme|*Proteomics|mRNA|Mutation|DNAH1 protein, human|Dyneins|SPAG6 protein, mouse|Microtubule Proteins|SPEF2 protein, mouse 93 ALCAM 32629311 Neurobiol. Aging 2020 10.1016/j.neurobiolaging.2020.04.017 0 0 0 337 Animals|Humans|*Zebrafish|*Aging|*Brain|*Sequencing, RNA|Alzheimer Disease|*Base Sequence|Gene Expression Profiling|*Whole Exome Sequencing|*Cell Adhesion Molecules|ALCAM protein, human|Cell Adhesion Molecules, Neuronal|ALCAM|Fetal Proteins|Antigens, CD 689 ALCAM 32596059 PeerJ 2020 PMC7307565 10.7717/peerj.9394 0 0 0 337 Humans|*Sarcoma, Alveolar Soft Part|*Transcriptome|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Translocation, Genetic|Oncogene Proteins, Fusion|Intracellular Signaling Peptides and Proteins|Soft Tissue Neoplasms|RNA, Messenger|*Connective Tissue 689 ALCAM 32593508 Reprod. Biomed. Online 2020 10.1016/j.rbmo.2020.05.002 0 0 0 337 Female|*Cumulus Cells|*Luteal Phase|*Oocytes|*Menstrual Cycle|Follicular Phase|Ovulation Induction|*Gene Expression 689 ALCAM 32580944 J. Biol. Chem. 2020 10.1074/jbc.RA120.013758 0 0 0 337 Humans|*Membrane Proteins|*Amino Acids|ADAM10 Protein|ADAM Proteins|ADAM17 Protein|Amyloid Precursor Protein Secretases|Cell Membrane|Amino Acid Sequence|Exon|Activated-Leukocyte Cell Adhesion Molecule|Alternative Splicing|HEK293 Cells|Protein Processing, Post-Translational 689 ALCAM 32550557 Gene X 2020 PMC7285916 10.1016/j.gene.2020.100031 0 0 0 337 Humans|Mesenchymal Stromal Cells|Bone Marrow Cells|Cell Differentiation|Cells, Cultured|Thy-1 Antigens|NT5E protein, human|5'-Nucleotidase|Fibroblasts|Biomarkers|Cell Proliferation|Antigens, CD|Flow Cytometry|GPI-Linked Proteins 689 ALCAM 32460901 Arthritis Res. Ther. 2020 PMC7251704 10.1186/s13075-020-02209-9 0 0 0 337 Humans|*Lupus Nephritis|*Activated-Leukocyte Cell Adhesion Molecule|*Biomarkers|ALCAM protein, human|*Fetal Proteins|*Antigens, CD|*Cell Adhesion Molecules, Neuronal|Kidney|*Urinary Tract 689 ALCAM 32380056 Exp. Mol. Pathol. 2020 10.1016/j.yexmp.2020.104443 0 0 0 337 *Activated-Leukocyte Cell Adhesion Molecule|*Prognosis|Neoplasm Recurrence, Local|ALCAM protein, human|*Fetal Proteins|*Cell Adhesion Molecules, Neuronal|*Antigens, CD|*Biomarkers, Tumor|*Neoplastic Processes|*Cancer Stem Cell|Cell Movement 689 ALCAM 32366845 Nat Commun 2020 PMC7198599 10.1038/s41467-020-15986-3 1 0 0 337 Humans|*Lupus Nephritis|*Ethnicity|*Biomarkers|VCAM-1|Kidneys|ROC Curve|*Urinary Tract|Longitudinal Studies|Urinalysis|ELISA 689 ALCAM 32287057 AIDS 2020 10.1097/QAD.0000000000002540 0 0 0 337 *HIV-1|*Activated-Leukocyte Cell Adhesion Molecule|ALCAM protein, human|*Fetal Proteins|*Cell Adhesion Molecules, Neuronal|CD4 Lymphocyte Count|*Antigens, CD|*Disease Progression|HIV Infections|*HIV Seropositivity|Genotype|Host-Pathogen Interactions|Polymorphism, Single Nucleotide 689 ALCAM 32217757 J Immunother Cancer 2020 PMC7174071 10.1136/jitc-2019-000172 0 0 0 337 Humans|*Cancer|ALCAM protein, human|Antigens, CD|Antigens, Differentiation, T-Lymphocyte|Activated-Leukocyte Cell Adhesion Molecule|CD3 Complex|Fetal Proteins|Synapse, Immunological|Cell Adhesion Molecules, Neuronal|Lymphocyte|Cell Differentiation|Antibodies, Monoclonal 689 ALCAM 32196701 Cell Biochem. Funct. 2020 10.1002/cbf.3525 0 0 0 337 Humans|*Tamoxifen|*ALCAM|Neoplasm Recurrence, Local|ALCAM protein, human|*Fetal Proteins|*Cell Adhesion Molecules, Neuronal|*Antigens, CD|Antineoplastic Agents, Hormonal|MCF7 Cells|*Single-Chain Antibodies|Drug Resistance, Neoplasm|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic 689 ALCAM 32193381 Nat Commun 2020 PMC7081352 10.1038/s41467-020-15303-y 3 0 0 337 *Clathrin|ALCAM protein, human|Fetal Proteins|Cell Adhesion Molecules, Neuronal|LGALS8 protein, human|*Galectins|Antigens, CD|*Endocytosis|Biomarkers, Tumor|Cell Line, Tumor|Cell Membrane 689 ALCAM 32193075 Transl Oncol 2020 PMC7078545 10.1016/j.tranon.2020.100753 0 0 0 337 *Soil|*Molecular Targeted Therapy|Calgranulin A|S100A9 Protein|Cell Movement|MCAM protein, human|Melanoma Cell Adhesion Molecule|Basigin|Melanoma|Epithelial-Mesenchymal Transition|Cell Proliferation|Lung Neoplasms|Transductions, Signal|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Upregulation|ALCAM protein, human|Fetal Proteins 689 ALCAM 32174798 Int. 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Sci. 2020 PMC7053324 10.7150/ijbs.39768 0 0 0 337 MicroRNAs|*Melanoma|Gene Expression Regulation, Neoplastic|RNA Interference|*Disease Progression|Cell Proliferation|Cell Line, Tumor 689 ALCAM 32159142 Mater Today Bio 2020 PMC7061691 10.1016/j.mtbio.2019.100005 1 0 0 337 Humans|Animals|Rabbits|*Hydroxyapatite|*Biomimetics|Bone Substitutes|*Collagen|Osteogenesis|Tissue Scaffolds|Bone Regeneration|*Bone|Mesenchymal Stem Cells|Cell Differentiation|Biomimetic Materials|Cells, Cultured|Porosity 689 ALCAM 32085563 Cancers (Basel) 2020 PMC7072229 10.3390/cancers12020470 0 0 0 337 Humans|*Activated-Leukocyte Cell Adhesion Molecule|*Laryngeal Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Prognosis|Head and Neck Neoplasms|Carcinoma, Squamous Cell|*Transcriptome Analysis|ALCAM protein, human|*Fetal Proteins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Antigens, CD|*Cell Adhesion Molecules, Neuronal|Lymphatic Metastasis|Neoplasm Recurrence, Local|Brazil 689 ALCAM 32064501 Neuro-oncology 2020 10.1093/neuonc/noaa028 0 0 0 337 *Carcinoma, Non-Small-Cell Lung|*Activated-Leukocyte Cell Adhesion Molecule|*Endothelium, Vascular|*Lung Neoplasms|ALCAM protein, human|*Fetal Proteins|*Cell Adhesion Molecules, Neuronal|*Antigens, CD|*Brain Neoplasms|Prognosis|Cell Movement|Cell Adhesion|Cell Line, Tumor|Cell Adhesion Molecules 689 ALCAM 31938574 PeerJ 2020 PMC6953351 10.7717/peerj.8196 0 0 0 337 Humans|Female|Pregnancy|*DNA Methylation|CpG Islands|Epigenesis, Genetic|*Recurrent Miscarriage|Promoter Regions, Genetic|Oligonucleotide Array Sequence Analysis|Gene Ontology|Genome|Biological Markers 689 aloe 32673718 Int. 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Cell 2020 PMC7340272 10.1016/j.molcel.2020.05.021 0 0 0 111 BRCA2 protein, human|*BRCA2 Protein|BRCA1 protein, human|*BRCA1 Protein|Endonuclease, Apurinic|*Endonucleases|DNA Repair|*DNA|DNA Damage|Synthetic Lethality|Multifunctional Enzymes 121 APEX2 32477404 Front Genet 2020 PMC7235407 10.3389/fgene.2020.00450 0 0 0 111 Animals|*Chromatin|Biotinylation|Protein Interaction Mapping|Mass Spectrometry|Chromatography, Affinity|DNA|Biological Assay 121 APEX2 32470320 Cell Chem Biol 2020 10.1016/j.chembiol.2020.05.006 0 0 0 111 Humans|Animals|*Peroxidase, Ascorbate|*Saccharomyces cerevisiae|*Proteomics|*Yeast, Dried|*Gene Expression Profiling|Biotinylation|Biotin|Proteome|Transcriptome|RNA|Mitochondria|Staining and Labeling|HEK293 Cells 121 APEX2 32467232 J. Biol. 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Cell 2020 10.1016/j.molcel.2019.12.028 1 0 0 111 Humans|*Ubiquitin|*AMP-Activated Protein Kinases|Proteomics|*Lysosomes|*Autophagy|*System, Signal Transduction|LGALS9 protein, human|*Galectin|TOR Serine-Threonine Kinases|Ubiquitination|Intracellular Membranes|Mycobacterium tuberculosis|HeLa Cells|HEK293 Cells 121 APOBEC3D 32533515 Int. J. 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Sci. 2020 10.1167/iovs.61.5.17 0 0 0 56 *Genetic Predisposition to Disease|Retinal Drusen|Macular Degeneration|Complement Factor H|Polymorphism, Single Nucleotide|*Disease Progression|Phenotype|Diet, Mediterranean|*Retina|Risk Factors 459 ARMS2 32406777 Ophthalmic Genet. 2020 10.1080/13816810.2020.1765396 0 0 0 56 459 ARMS2 32383840 Retina (Philadelphia, Pa.) 2020 10.1097/IAE.0000000000002825 0 0 0 56 *Geographic Atrophy|*Age Related Macular Degeneration|Ranibizumab|Fluorescein Angiography|Bevacizumab|Angiogenesis Inhibitors|Intravitreal Injections|Visual Acuity|Tomography, Optical Coherence|Vascular Endothelial Growth Factor A|Incidence|*Optic Nerve|Atrophy 459 ARMS2 32371126 Ophthalmol Retina 2020 10.1016/j.oret.2020.04.014 0 0 0 56 *Geographic Atrophy|*Age Related Macular Degeneration|Retinal Drusen|*Genotype|*Phenotype|Fluorescein Angiography|Retrospective Studies|Polymorphism, Single Nucleotide|Risk Factors 459 ARMS2 32346038 Sci Rep 2020 10.1038/s41598-020-64301-z 0 0 0 56 Humans|aflibercept|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Visual Acuity|Wet Macular Degeneration|*Complement Factor B|*Receptors, Vascular Endothelial Growth Factor|*Recombinant Fusion Proteins|Choroidal Neovascularization|Gene Frequency|Genotype|Choroid|Fluorescein Angiography|Complement Factor H|Allele|Polymorphism, Single Nucleotide|SKIV2L protein, human|DNA Helicases 459 ARMS2 32270179 Endocrinology 2020 10.1210/endocr/bqaa057 0 0 0 56 Humans|Female|Pregnancy|Child|Child, Preschool|*Vitamin D|Case-Control Studies|*Vitamins|*Placentas|Vitamin D Deficiency|*Cholestanes|Chorioamnionitis|Asthma|*Phenotypes|Cohort Studies|MACC1 protein, human|Transcription Factors 459 ARMS2 32195675 Asia Pac J Ophthalmol (Phila) 2020 10.1097/01.APO.0000656976.47696.7d 0 0 0 56 Humans|Aged|Genome-Wide Association Study|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Visual Acuity|Wet Macular Degeneration|Choroidal Neovascularization|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Linkage Disequilibrium|Genotype|Asian Continental Ancestry Group|SKIV2L protein, human|DNA Helicases|Case-Control Studies|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1 459 ARMS2 32191267 JAMA Ophthalmol 2020 PMC7082767 10.1001/jamaophthalmol.2020.0437 0 0 0 56 *Incidence|*Age Related Macular Degeneration|Ranibizumab|Bevacizumab|Geographic Atrophy|Angiogenesis Inhibitors|Choroidal Neovascularization|Intravitreal Injections|Fluorescein Angiography|Antibodies, Monoclonal, Humanized|Visual Acuity|Vascular Endothelial Growth Factor A|Vascular Endothelial Growth Factors|Cohort Studies|Risk Factors|*Atrophy 459 ARMS2 32163116 JAMA Ophthalmol 2020 PMC7068673 10.1001/jamaophthalmol.2020.0266 0 0 0 56 Humans|*Incidence|*Risk Factors|*Retinal Drusen|Fluorescein Angiography|Macular Degeneration|Tomography, Optical Coherence|Complement Factor H|Diagnostic Techniques, Ophthalmological|Photography|Multimodal Imaging 459 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Inhibitors|Tomography, Optical Coherence|Fundus Oculi|Antibodies, Monoclonal, Humanized|Follow-Up Studies|Combined Modality Therapy 459 ARMS2 31988359 Sci Rep 2020 PMC6985219 10.1038/s41598-020-57747-8 0 0 0 56 Humans|*Central Serous Chorioretinopathy|*Retinal Detachment|*Age Related Macular Degeneration|Fluorescein Angiography|Choroidal Neovascularization|Coherence Tomography, Optical|Choroid|Retinal Pigment Epithelium|Visual Acuity|Fundus Oculi|Indocyanine Green|Coloring Agents|Single Nucleotide Polymorphisms|Genotype 459 ARMS2 31970928 Acta Ophthalmol 2020 10.1111/aos.14357 1 0 0 56 complement factor H, human|*Complement Factor H|Czech Republic|High-Temperature Requirement A Serine Peptidase 1|Macular Degeneration|Serine Endopeptidases|Gene Frequency|Polymorphism, Single Nucleotide|Genotype|Complement C3|Proteins 459 ARMS2 31942429 Taiwan J Ophthalmol 2020 PMC6947742 10.4103/tjo.tjo_72_19 0 0 0 56 Humans|*Ranibizumab|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Visual Acuity|Wet Macular Degeneration|complement factor H, human|Complement Factor H|Intravitreal Injections|High-Temperature Requirement A Serine Peptidase 1|Polymorphism, Single Nucleotide|Fluorescein Angiography|Antibodies, Monoclonal, Humanized|Genotype|Pharmacogenetics|*Hispanic|HtrA1 protein, human 459 ARMS2 31916060 Int Ophthalmol 2020 10.1007/s10792-019-01274-7 0 0 0 56 Humans|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Visual Acuity|Wet Macular Degeneration|Complement C2|Complement Factor H|Complement Factor B|Polymorphism, Single Nucleotide|Genotype|Complement C3|Fluorescein Angiography 459 ARMS2 31899035 Ophthalmology 2020 PMC7246151 10.1016/j.ophtha.2019.11.016 0 0 0 56 *Incidence|*Macular Degeneration|Geographic Atrophy|Retinal Drusen|Prospective Studies|Visual Acuity|*Anetoderma|Risk Factors|Atrophy 459 ASTL 32519853 J Chem Inf Model 2020 10.1021/acs.jcim.0c00380 0 0 0 52 *HSP90 Heat-Shock Proteins|*Molecular Chaperones|Allosteric Regulation|Protein Conformation|Molecular Dynamics Simulation|Molecular Docking Simulation|Protein Binding|ATPase|*Signal Transduction|TP53 protein, human|Tumor Suppressor Protein p53 96 ASTL 32495721 Thyroid 2020 10.1089/thy.2019.0802 0 0 0 52 96 ASTL 32492340 J Chem Theory Comput 2020 10.1021/acs.jctc.0c00280 0 0 0 52 *Phosphorylation|*HSP90 Heat-Shock Proteins|*Molecular Chaperones|Chaperonins|Allosteric Regulation|Protein Binding|Protein Conformation|Cell Cycle Proteins|Molecular Dynamics Simulation 96 ASTL 32361982 J Neurol Surg A Cent Eur Neurosurg 2020 10.1055/s-0040-1709165 0 0 0 52 Humans|*Meningioma|*Smell|Meningeal Neoplasms|Olfaction Disorders|Functional Magnetic Resonance Imaging|Postoperative Period|Postoperative Complications 96 ASTL 31935082 J Chem Inf Model 2020 10.1021/acs.jcim.9b01045 0 0 0 52 Humans|*Allosteric Regulation|*HSP70 Heat-Shock Proteins|*Molecular Chaperones|Protein Conformation|*Post-Translational Modifications|Adenosinetriphosphatase|Protein Binding|Molecular Dynamics Simulation|Binding Sites|Protein Domains 96 ASXL3 32517662 BMC Pediatr 2020 PMC7282141 10.1186/s12887-020-02027-7 0 0 0 48 Child|Humans|Infant|Retrospective Studies|Phenotype|Developmental Disabilities|Mutation|Syndrome|Transcription Factors|Diagnostic Imaging|China|ASXL3 protein, human 49 ASXL3 32240826 Eur J Med Genet 2020 10.1016/j.ejmg.2020.103925 0 0 0 48 Child|Humans|*Mosaicism|*Syndrome|Whole Exome Sequencing|Exome|Developmental Disabilities|Phenotype|Intellectual Disability|Siblings|Mutation|ASXL3 protein, human|Transcription Factors 49 ASXL3 32219835 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.04.022 0 0 0 48 Child|Humans|*High-Throughput Nucleotide Sequencing|Mental Retardation|Developmental Disabilities|Phenotype|Failure to Thrive|Transcription Factors|Mutation|Syndrome|ASXL3 protein, human 49 ASXL3 32132929 Front Physiol 2020 PMC7040374 10.3389/fphys.2020.00075 0 0 0 48 Child|Humans|Developmental Disabilities|Phenotype|Transcription 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Patterns 2020 10.1016/j.gep.2020.119126 0 0 0 363 Mice|Animals|*Zebrafish|Activating Transcription Factors|Cell Differentiation|Olfactory Bulbs|Sensory Neurons|Gene Expression Regulation|*Cyclic AMP Response Element-Binding Protein|Mice, Knockout|Smell 162 ATF5 32603335 PLoS ONE 2020 PMC7326155 10.1371/journal.pone.0225044 0 0 0 363 MIRN520 microRNA, human|*miRNA|3' Untranslated Region|Apoptosis|Cell Line, Tumor|Endoplasmic Reticulum Stress|Cell Proliferation|mRNA|*Cyclic AMP Response Element-Binding Protein|Transcriptional Activation|Binding Sites|Activating Transcription Factors 162 ATF5 32551949 Am. J. Respir. Cell Mol. 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Psychiatry 2020 10.1038/s41380-020-0806-5 0 0 0 218 Humans|*Down Syndrome|Amyloid Precursor Protein Secretases|*Alzheimer Disease|*Trisomy|Aspartic Acid Endopeptidases|*Organoids|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|*Brain 242 BACE2 32566665 Biomed Res Int 2020 PMC7293731 10.1155/2020/1920789 0 0 0 218 *Proteasome Endopeptidase Complex|Aspartic Acid Endopeptidases|Amyloid Precursor Protein Secretases|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|Alzheimer Disease|Cells, Cultured 242 BACE2 32378555 Biol. Pharm. Bull. 2020 10.1248/bpb.b19-00720 0 0 0 218 Animals|Cricetinae|*Amyloid beta-Protein Precursor|Amyloid Precursor Protein Secretases|*Cricetulus|*Gentiana|Aspartic Acid Endopeptidases|*CHO Cells|Presenilin-1|Amyloid beta-Peptides|Alzheimer Disease|Neprilysin|Disease Models, Animal|*Flower|Plant Extracts 242 BACE2 32276567 J. Biomol. Struct. 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Psychiatry 2020 10.1016/j.biopsych.2020.02.001 0 0 0 218 BACE1 protein, human|*Amyloid Precursor Protein Secretases|*Alzheimer Disease|*Aspartic Acid Endopeptidases|Amyloid beta-Protein Precursor|Amyloid beta-Peptides 242 BACE2 32216238 Zhonghua Nan Ke Xue 2020 0 0 0 218 Humans|Male|*RNA, Long Noncoding|*Prostate|*Prostate Cancer|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Movement|Gene Knockdown Techniques|RNA, Small Interfering|Transfection|Signal Transduction|RP1 protein, human|Eye Proteins 242 BACE2 32160867 BMC Mol Cell Biol 2020 PMC7066761 10.1186/s12860-020-00260-7 2 0 0 218 Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|*Proteasome Endopeptidase Complex|Neurodegenerative Diseases|*Lysosome|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|Alzheimer Disease|Neuritic Plaques|Peptide Fragments|Neurons 242 BANK1 32153635 Front Genet 2020 PMC7045059 10.3389/fgene.2020.00058 0 0 0 136 86 BARHL2 32483163 Sci Rep 2020 PMC7264323 10.1038/s41598-020-65435-w 0 0 0 57 Animals|*Retinal Ganglion Cells|*Zebrafish|Amacrine Cells|Retina|Transcription Factors|Homeodomain Proteins|Cell Lineage|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|Nerve Tissue Proteins|Axons|Brain 30 BARX1 32616504 Biol Open 2020 PMC7331463 10.1242/bio.052043 0 0 0 95 *Neural Crest|*Branchial Region|*Hedgehog Proteins|*Signal Transduction|*Transcription Factor|Body Patterning|Mesoderm|Homeodomain Proteins|Gene Expression Regulation, Developmental|Cartilage|Face 100 BARX1 32571211 BMC Genomics 2020 PMC7310078 10.1186/s12864-020-06825-2 0 0 0 95 *Mesenchymal Stem Cells|*Transcriptome|Bone Marrow Cells|*Sequencing, RNA|Cell Differentiation|Adipose Tissue|Cells, Cultured|Gene Expression Profiling|Immunophenotyping|*Base Sequence|Cell Proliferation|*Whole Exome Sequencing|RNA 100 BARX1 31969372 Cancer Epidemiol. Biomarkers Prev. 2020 10.1158/1055-9965.EPI-19-1281 0 0 0 95 *Esophageal Cancer|Genetic Predisposition to Disease|Genetic Variation|Risk Factors 100 BASP1 32514259 Clin Proteomics 2020 PMC7257173 10.1186/s12014-020-09285-8 0 0 0 707 *Alzheimer Disease|Reproducibility of Results|Proteomics|tau Proteins|Amyloid beta-Peptides|*Biomarkers|*Brain|Peptide Fragments|Cognitive Impairment|*Mass Spectrometry|Specificity 136 BASP1 32351715 Cell Death Discov 2020 PMC7181654 10.1038/s41420-020-0263-6 0 0 0 707 Humans|*RNA, Long Noncoding|*Cell Differentiation|*Transcriptome Analysis|*Neurons|Neural Stem Cells|TCF12 protein, human|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Proliferation|Transcription Factor|Neurite 136 BASP1 32084215 PLoS ONE 2020 PMC7034829 10.1371/journal.pone.0229308 0 0 0 707 *Intracranial Aneurysm|Ruptured Aneurysms|Subarachnoid Hemorrhage|Cerebral Artery|Gene Expression Profiling|Transcriptome|Biomarkers|Genes, Regulator|Real-Time PCR, Quantitative 136 BASP1 31975592 J. Proteome Res. 2020 10.1021/acs.jproteome.9b00800 0 0 0 707 Humans|Animals|*Mitophagy|*Proteomics|*Mitochondria|parkin protein|Ubiquitin-Protein Ligases|Carbonyl Cyanide m-Chlorophenyl Hydrazone|Autophagy|HeLa Cells|Protein Transport 136 BASP1 31954705 Eur. J. Pharmacol. 2020 10.1016/j.ejphar.2020.172935 0 0 0 707 *Muscle, Smooth, Vascular|*Cell Survival|*Myocytes, Smooth Muscle|Long Non-Coding RNA|Cell Proliferation|MicroRNAs|Apoptosis|Aneurysm, Abdominal Aortic|Cell Movement|Transfection 136 BASP1 31944520 Mol Oncol 2020 PMC7053243 10.1002/1878-0261.12636 0 0 0 707 Humans|*Calmodulin|v-myc Oncogene|*Oncogenes|*Transcription Factor|Cell Transformation, Neoplastic|*Oncogenesis|*Genes, Regulator|Proto-Oncogene Proteins c-myc|Calmodulin-Binding Proteins|Gene Expression Regulation|Nerve Tissue Proteins|Activation, Transcriptional|Cell Proliferation|Brain|BASP1 protein, human|Membrane Proteins|Repressor Proteins 136 Bbx 32661279 Nat Plants 2020 10.1038/s41477-020-0725-0 0 0 0 145 Arabidopsis Proteins|Arabidopsis|Hypocotyl|Gene Expression Regulation, Plant|Basic-Leucine Zipper Transcription Factors|Transcription Factors|Nuclear Proteins|Ubiquitin-Protein Ligases|Seedlings|Light|Plants, Genetically Modified|Protein Binding|HY5 protein, Arabidopsis 73 Bbx 32654323 Plant J. 2020 10.1111/tpj.14929 0 0 0 145 *Hypocotyl|Arabidopsis Proteins|Arabidopsis|Basic-Leucine Zipper Transcription Factors|Gene Expression Regulation, Plant|Seedlings|Transcription Factors|Plants, Transgenic|Nuclear Proteins|Ubiquitin-Protein Ligases|Light Signal Transduction|Transcriptional Activation|Promoter Regions, Genetic|Darkness|HY5 protein, Arabidopsis 73 Bbx 32552524 Plant Signal Behav 2020 10.1080/15592324.2020.1782647 0 0 0 145 *Computational Biology|Arabidopsis Proteins|Arabidopsis|Gene Expression Regulation, Plant|Transcription Factors|Basic-Leucine Zipper Transcription Factors|Nuclear Proteins|Repressor Proteins|Plant Development|Light 73 Bbx 32537777 J. Cell. Physiol. 2020 10.1002/jcp.29875 0 0 0 145 Humans|dentin sialophosphoprotein|Sialoglycoproteins|Phosphoproteins|Extracellular Matrix Proteins|Odontoblasts|Enamel Organ|Cell Differentiation|Tooth Root|Mesenchyme|Dentin|Molar|Transcription Factors|Cell Proliferation 73 Bbx 32488968 Plant J. 2020 10.1111/tpj.14863 0 0 0 145 73 Bbx 32347061 Sheng Wu Gong Cheng Xue Bao 2020 10.13345/j.cjb.190302 0 0 0 145 Phytohormones|*Plants|Gene Expression Regulation, Plant|Plant Proteins|Transcription Factors|Abiotic Stress Responses|Plant Development|Plant Diseases|Signal Transduction|Amino Acid Sequence 73 Bbx 32338177 Plant Signal Behav 2020 10.1080/15592324.2020.1752534 0 0 0 145 *Lycopersicon esculentum|*Fruit|*Rosa|*Indigo Carmine|Anthocyanins|*Transcriptome|Gene Expression Regulation, Plant|Plant Proteins|*Indigofera|Transcriptome Analysis|Transcription Factors|*Color 73 Bbx 32237198 J Integr Plant Biol 2020 10.1111/jipb.12935 0 0 0 145 Transcription Factors|Gene Expression Regulation, Plant|Arabidopsis Proteins|Arabidopsis|Plant Proteins|TYRP1 protein, human|Plant Development|*Membrane Glycoproteins|Light Signal Transduction|Light 73 Bbx 32054455 BMC Plant Biol. 2020 PMC7020368 10.1186/s12870-020-2239-3 0 0 0 145 *Fruit|Gene Expression Regulation, Plant|Genome, Plant|Multigene Family|Plant Proteins|Transcription Factors|Transcriptome|Vitis|Gene Expression Profiling|Zinc Finger|Rice|Arabidopsis|Stress, Physiological|Plant Development|Phylogeny 73 Bbx 32034034 Plant Cell 2020 PMC7145486 10.1105/tpc.19.00641 0 0 0 145 jasmonic acid|*Ipomoea batatas|*Fusarium|*Oxylipins|*Cyclopentanes|Gene Expression Regulation, Plant|Plant Proteins|Plant Diseases|Plants, Genetically Modified|Stress, Physiological 73 BCAM 32664893 BMC Med Educ 2020 10.1186/s12909-020-02132-2 0 0 0 650 Female|Humans|*Universities|*Students, Medical|*Cross-Sectional Studies|Breast Self-Examination|Early Detection of Cancer|Health Knowledge, Attitudes, Practice|Awareness|Prognosis|Surveys and Questionnaires|Health Personnel|*Knowledge|*Rare Diseases 232 BCAM 32654899 Vaccine 2020 PMC7347470 10.1016/j.vaccine.2020.06.079 0 0 0 650 Child|Humans|*Dengue Vaccines|Philippines|Cohort Studies|Dengue|Dengue Virus|Fever Vaccine, Yellow|Severe Dengue|Vaccines, Attenuated|Vaccination|Antibodies, Neutralizing|Hospitalization 232 BCAM 32640509 Biomedicines 2020 10.3390/biomedicines8070195 0 0 0 650 *RNA|Molecular Dynamics Simulation|Thermodynamics|*Nanotubes|Water 232 BCAM 32631199 Plant Dis. 2020 10.1094/PDIS-10-19-2130-RE 0 0 0 650 *Prunus persica|*Fungicides, Industrial|Spain|*Ascomycota|Plant Diseases|Fruit|Incidence 232 BCAM 32571210 BMC Evol. Biol. 2020 PMC7310121 10.1186/s12862-020-01635-2 0 0 0 650 *Arabidopsis|*Genetic Drift|Genetics, Population|Gene Flow|Genetic Variation|Genotype|Genome, Plant|Genomics|Geography|Environment|SNPs|Europe 232 BCAM 32539723 BMC Public Health 2020 PMC7296642 10.1186/s12889-020-09010-y 0 0 0 650 Female|Humans|Tanzania|Breast Self-Examination|*Patient Acceptance of Health Care|Early Detection of Cancer|Health Knowledge, Attitudes, Practice|Mass Screening|*Cancer|Surveys and Questionnaires|Risk Factors|Age Factors|*Knowledge 232 BCAM 32503615 Respir. Res. 2020 PMC7275482 10.1186/s12931-020-01395-z 0 0 0 650 Humans|*Quality of Life|Forced Expiratory Volume|Pulmonary Disease, Chronic Obstructive|Surveys and Questionnaires|Dyspnea|Severity of Illness Index|*Complement Factor B 232 BCAM 32458360 CNS Drugs 2020 10.1007/s40263-020-00737-1 0 0 0 650 *Alzheimer Disease|Amyloid Plaques|Neurofibrillary Tangles|Amyloid beta-Peptides|tau Proteins|Amyloid|Amyloidosis|Amyloidogenic Proteins 232 BCAM 32442627 Neural Netw 2020 10.1016/j.neunet.2020.04.030 0 0 0 650 Humans|Neural Networks, Computer|Machine Learning|Image Processing, Computer-Assisted|Algorithms|Color 232 BCAM 32412752 J. Am. Chem. Soc. 2020 10.1021/jacs.0c02549 0 0 0 650 *Polyketide Synthases|*Cheminformatics|Substrate Specificity|Amino Acid Sequence|Protein Engineering|Protein Structure, Tertiary 232 BCAM 32368654 Heliyon 2020 PMC7184173 10.1016/j.heliyon.2020.e03819 0 0 0 650 Humans|Female|*Universities|*Students, Medical|Syria|Early Detection of Cancer|Breast Self-Examination|Health Knowledge, Attitudes, Practice|Surveys and Questionnaires|*Knowledge|Cross-Sectional Studies 232 BCAM 32272567 Bioengineering (Basel) 2020 10.3390/bioengineering7020035 0 0 0 650 *Therapies, Radiofrequency|*Pain Management|Finite Element Analysis|Computer Simulation|Temperature|Models, Biological|Electricity|Pain|Catheter Ablation|Tissues, Muscle 232 BCAM 32233691 Electromagn Biol Med 2020 10.1080/15368378.2020.1741383 0 0 0 650 *Hyperthermia, Induced|Catheter Ablation|Microwaves|Liver Neoplasms|*Models, Computerized|Treatment Outcome 232 BCAM 32156770 BMJ Open 2020 PMC7064072 10.1136/bmjopen-2019-035911 0 0 0 650 Humans|Female|*Psychometrics|*Cross-Sectional Studies|Factor Analysis, Statistical|Reproducibility of Results|Surveys and Questionnaires|*Chinese 232 BCAM 32116031 Comput Methods Biomech Biomed Engin 2020 10.1080/10255842.2020.1733991 0 0 0 650 *RNA|*Nanotubes|Nanotechnology|Models, Chemical|Nanostructures|Molecular Dynamics Simulation|Elasticity|Stress, Mechanical 232 BCAM 32015018 Genetics 2020 PMC7153926 10.1534/genetics.119.302949 0 0 0 650 Quantitative Trait Loci|Phenotype|Models, Genetic|Algorithms 232 BCAM 31951095 Mol Oncol 2020 PMC7138403 10.1002/1878-0261.12638 0 0 0 650 Humans|*RNA, Long Noncoding|*Stomach Neoplasms|*Up-Regulation|*Transcriptional Activation|Cell Migration|Neoplasm Invasiveness|Prognosis|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Proliferation|Lymphatic Metastasis|Cell Line, Tumor|Biomarkers, Tumor|mRNA 232 BCORL1 32655615 Front Genet 2020 PMC7324646 10.3389/fgene.2020.00560 0 0 0 82 Humans|Pakistan|*Leukemia, Myeloid, Acute|Mutations|Sequencing, Next-Generation|Exome|Nuclear Proteins|Codon, Nonsense|Asian Continental Ancestry Group 58 BCORL1 32628469 Biochemistry 2020 10.1021/acs.biochem.0c00285 0 0 0 82 *Polycomb Repressive Complex 1|KDM2A protein, human|Jumonji Domain-Containing Histone Demethylases|F-Box Proteins|Histone|Proto-Oncogene Proteins|*Cell Nucleus 58 BCORL1 32606114 BMJ Case Rep 2020 10.1136/bcr-2019-234208 0 0 0 82 Female|Humans|Middle Aged|*Thyroid Cancer, Papillary|*Proto-Oncogene Proteins B-raf|*Thyroid Cancer|*Mutations|Carcinoma, Papillary|Thyroid Nodule|Thyroidectomy|*Adenocarcinoma|Thyroid Gland|BCORL1 protein, human|*Repressor Proteins|BRAF protein, human 58 BCORL1 32594217 Ann. Hematol. 2020 10.1007/s00277-020-04154-8 0 0 0 82 Humans|Epigenesis, Genetic|*Red-Cell Aplasia, Pure|*Mutation|Anemia|Immunosuppressive Agents|Immunosuppression|Remission Induction 58 BCORL1 32516392 Endocrinology 2020 10.1210/endocr/bqaa094 0 0 0 82 Pregnancy|Female|Humans|Sheep|Animals|*Theca Cells|*Testosterone|Ovarian Follicle|Dihydrotestosterone|Polycystic Ovary Syndrome|Ovary|Granulosa Cells|*Gene Expression Regulation|*Testosterone Congeners|granulose|*Polysaccharides|*Luteal Cells|Prenatal Exposure Delayed Effects|Gene Expression 58 BCORL1 32376790 J. Med. Genet. 2020 10.1136/jmedgenet-2019-106598 0 0 0 82 Humans|Male|*Chromosomes, Human, X|*Exome|Spermatogenesis|Infertility, Male|*Whole Exome Sequencing|Testis|Genes, X-Linked 58 BCORL1 32118206 Neurooncol Adv 2020 PMC7034640 10.1093/noajnl/vdaa009 0 0 0 82 Humans|Reproducibility of Results|Gliomas|*Sequencing, Next-Generation|Isocitrate Dehydrogenase|Brain Neoplasms|Prognosis|Mutation|Biomarkers, Tumor|Los Angeles 58 BCORL1 32011345 Am. J. Surg. Pathol. 2020 10.1097/PAS.0000000000001445 0 0 0 82 Humans|Female|*Adenosarcoma|In Situ Hybridization, Fluorescence|Sarcoma, Endometrial Stromal|Immunohistochemistry|Endometrial Neoplasms|Uterine Neoplasms|Biomarkers, Tumor|Repressor Proteins|BCOR protein, human|Proto-Oncogene Proteins 58 BEND3 32630636 Antioxidants (Basel) 2020 10.3390/antiox9070573 0 0 0 121 Mice|Animals|*Polyphenols|*Plants, Medicinal|*Endothelial Cells|*Oxidative Stress|*Hyperglycemia|NFE2L2 protein, human|NF-E2-Related Factor 2|*Biomarkers|Redox|NOS3 protein, human|Endothelial Nitric Oxide Synthase|Antioxidants|superoxide dismutase 2|Mn-SOD|Nuclear Factor-Kappab|Reactive Oxygen Species|Inflammation|Signal Transduction 93 BEND3 32233376 Anal. Chem. 2020 10.1021/acs.analchem.0c00376 0 0 0 121 Single-Cell Analysis|Trace Elements|*Spectrum Analysis|Mass Spectrometry 93 BEND3 32172875 Carbohydr Polym 2020 10.1016/j.carbpol.2020.116060 0 0 0 121 Animals|Mice|*Nanomedicine|Endothelial Cells|guar gum|Plant Gums|Galactans|Chitosan|Nanoparticles|Mannans|Drug Carriers|Doxorubicin|Drug Delivery Systems|*Polysaccharides|*Brain|pullulan|Glucans|rhodamine B|Rhodamines 93 BHLHA15 31892140 Int J Mol Sci 2020 PMC6981852 10.3390/ijms21010196 0 0 0 200 66 BLID 32467225 Genes Dev. 2020 PMC7328519 10.1101/gad.338194.120 0 0 0 49 Animals|Transcription Factor|Drosophila Proteins|Drosophila melanogaster|Drosophila|Body Patterning|Twist-Related Protein 1|Nuclear Proteins|Gene Expression Regulation, Developmental|Mesoderm 187 BMP2K 32413267 Biochem. Cell Biol. 2020 10.1139/bcb-2019-0381 0 0 0 204 *Fibroblasts|MicroRNAs|RNA Interference|Fibrosis|3' Untranslated Regions|Cell Proliferation|Cell Movement|Apoptosis|*SUMO-1 Protein|Up-Regulation|*Genes, Regulator|Downregulation|*Heart|ACTA2 protein, human|Actins 23 BMP2K 32322386 Cell Biosci 2020 PMC7161226 10.1186/s13578-020-00418-y 0 0 0 204 Humans|Child|*Leukemia, Megakaryoblastic, Acute|Megakaryocytes|Cell Differentiation|Thrombopoiesis|K562 Cells|Polyploidy|NOS2 protein, human|fasudil|1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine|2,5-dichloro-4-bromophenol|*Chlorophenols 23 BMP2K 32184967 ACS Med Chem Lett 2020 PMC7073879 10.1021/acsmedchemlett.9b00399 0 0 0 204 Protein-Serine-Threonine Kinases|Endocytosis 23 BMP2K 31927644 Mar. Biotechnol. 2020 10.1007/s10126-019-09940-8 1 0 0 204 Animals|*Genome-Wide Association Study|*Polymorphism, Single Nucleotide|*Bass|Quantitative Trait Loci|Genotype|Fish Proteins|Phenotype|Chromosomes|Breeding 23 BMP3 32590948 BMC Genomics 2020 PMC7318502 10.1186/s12864-020-06852-z 0 0 0 274 Female|Male|Animals|*Ducks|*Gonad|*Transcriptome Analysis|Ovaries|Transcriptome|Testes|Sex Differentiation|Gene Expression Regulation|*Cell Differentiation|*Aquatic Organisms 234 BMP3 32587131 Int J Stem Cells 2020 10.15283/ijsc20024 0 0 0 274 Humans|*Mesenchymal Stem Cells|Cranial Sutures|Craniosynostosis|Skull|Osteogenesis|*Suture 234 BMP3 32568738 Aging (Albany NY) 2020 PMC7343483 10.18632/aging.103422 0 0 0 274 Humans|Rats|Animals|*Synoviocytes|BMP3 protein, human|*Bone Morphogenetic Protein 3|*Rheumatoid Arthritis|Synovium|*Fibroblast|Arthritis, Adjuvant-Induced|MMP3 protein, human|Matrix Metalloproteinase 3|Tumor Necrosis Factor-alpha|Signal Transduction|Matrix Metalloproteinase 9|Cell Movement|Cells, Cultured|Bmp3 protein, rat 234 BMP3 32467348 Cancer Epidemiol. Biomarkers Prev. 2020 10.1158/1055-9965.EPI-19-1598 0 0 0 274 Humans|Adult|Middle Aged|*Colorectal Cancer|Occult Blood|Early Detection of Cancer|Colonoscopy|Screening|Feces|Sensitivity and Specificity|DNA|Incidence 234 BMP3 32415757 J Tissue Eng Regen Med 2020 10.1002/term.3056 0 0 0 274 Humans|*Osteogenesis|*Biocompatible Materials|fiberglass|Glass|Adipose Tissue-Derived Mesenchymal Stromal Cells|Tissue Scaffolds|Bone Regeneration|Cell Differentiation|Calcification, Physiologic|Bone 234 BMP3 32368260 Anim Reprod 2020 PMC7189511 10.21451/1984-3143-AR2018-0146 0 0 0 274 Female|Cattle|Animals|*Luteolysis|*Transforming Growth Factor beta|Corpus Luteum|Dinoprost|Granulosa Cells|mRNA|Signal Transduction|Transforming Growth Factors 234 BMP3 32112984 Gene 2020 10.1016/j.gene.2020.144511 0 0 0 274 Animals|*RNA, Long Noncoding|*Chickens|*Transcriptome|Transcriptome Analysis|mRNA|Sequencing, RNA|Gene Regulatory Networks|Signal Transduction|Toll-Like Receptor|Case-Control Studies 234 BMP3 32042865 Genes Dis 2020 PMC6997588 10.1016/j.gendis.2019.03.008 4 0 0 274 Animals|*Mesenchymal Stem Cells|Osteogenesis|*Transcriptome|Phosphatidylinositol 3-Kinases|*Cell Differentiation|*Bone Morphogenetic Proteins|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Growth Differentiation Factor 2|BMP2 protein, human|Growth Differentiation Factors|BMP7 protein, human|Bone Morphogenetic Protein 7|BMP3 protein, human|Bone Morphogenetic Protein 3|Transforming Growth Factor beta|BMP4 protein, human|Bone Morphogenetic Protein 4 234 BMP3 31996252 Stem Cell Res Ther 2020 PMC6990519 10.1186/s13287-020-1552-y 2 0 0 274 Humans|*Mesenchymal Stem Cells|*Adipocyte|recombinant human bone morphogenetic protein-2|*Transforming Growth Factor beta|*Signal Transduction|Bone Morphogenetic Protein 2|BMP4 protein, human|Bone Morphogenetic Protein 4|Cell Differentiation|BMP3 protein, human|Bone Morphogenetic Protein 3|Adipogenesis|BMP2 protein, human|GDF11 protein, human|Bone Morphogenetic Proteins|Cell Lineage 234 BMP3 31988704 Comput Struct Biotechnol J 2020 PMC6965205 10.1016/j.csbj.2019.12.014 0 0 0 274 Humans|*Stomach Neoplasms|*Bone Morphogenetic Proteins|BMPR1B protein, human|Bone Morphogenetic Protein Receptors, Type I|Bone Morphogenetic Protein Receptors|BMPR2 protein, human|Bone Morphogenetic Protein Receptors, Type II|Transforming Growth Factor beta|Bone Morphogenetic Protein 4|Bone Morphogenetic Protein 7|Bone Morphogenetic Protein 2|Signal Transduction|*Carrier Proteins|*Disease Progression|Cell Division|RNA, Messenger 234 BMP8B 32661178 Proc. Natl. Acad. Sci. U.S.A. 2020 10.1073/pnas.2000362117 0 0 0 137 Male|Humans|*Spermatogonia|*Signal Transduction|Adult Germline Stem Cells|Testis|Stem Cells|*Transcriptome Profiling|Cells, Cultured|Infertility, Male 74 BMP8B 32522588 Food Chem. Toxicol. 2020 10.1016/j.fct.2020.111487 0 0 0 137 Mice|Animals|phthalic acid|*C57BL Mice|3T3-L1|*Phthalic Acids|Adipogenesis|UCP1 protein, human|Uncoupling Protein 1|Brown Adipocyte|PPAR gamma|Thermogenesis|Adipose Tissue, Brown|Adipose Tissue, White|Diethylhexyl Phthalate|Rosiglitazone|Lipid Metabolism|Lipid Droplets|Glucose|Energy Metabolism 74 BMP8B 32521221 Stroke 2020 10.1161/STROKEAHA.120.029221 0 0 0 137 Humans|Animals|Mice|*Transcranial Direct Current Stimulation|*Stroke|*Brain Ischemia|Stroke Rehabilitation|Motor Cortex|Evoked Potentials, Motor|Recovery of Function|Functional Laterality|Neuronal Plasticity 74 BMP8B 32508963 Nutr Metab (Lond) 2020 PMC7266117 10.1186/s12986-020-00458-8 0 0 0 137 Rats|Animals|*Brown Fat|royal jelly|*Tocotrienols|*Thermogenesis|*Fat, White|*Fatty Acids|*Obesity|Uncoupling Protein 1|Diet, High-Fat|Energy Metabolism|*Energy Intake|Mitochondrial Proteins 74 BMP8B 32387807 Curr Opin Pharmacol 2020 10.1016/j.coph.2020.04.003 0 0 0 137 *Adipokines|Adipose Tissue, Brown|Muscle, Skeletal|Obesity|Adipocytes, Brown|*Cardiac Muscle|Exosomes|Adiponectin|fibroblast growth factor 21|Fibroblast Growth Factors|MicroRNAs|Exercise 74 BMP8B 32378263 J. Anim. Breed. Genet. 2020 10.1111/jbg.12481 0 0 0 137 Animals|*Feathers|*Chickens|*Skin|Gene Expression Profiling|Morphogenesis|Gene Expression Regulation, Developmental|*Phenotype|Signal Transduction|Genes, Homeobox 74 BMP8B 32338175 Physiol. Genomics 2020 PMC7311675 10.1152/physiolgenomics.00003.2020 0 0 0 137 Mice|Animals|*Networks, Gene|*Obesity|*Adiposity|*Phenotypes|Mice, Inbred Strains|Diabetes Mellitus|Quantitative Trait Loci|Adipose Tissue, Brown|Low-Fat Diets|*Genetic Background 74 BMP8B 32161290 Sci Rep 2020 PMC7066195 10.1038/s41598-020-60351-5 0 0 0 137 Female|Animals|*miRNA|*Goat|*mRNA|Hair Follicle|*Ovarian Follicle|Gene Expression Profiling|Hair|Fibroblasts|Reporter Gene|Skin|Luciferase|Inner Mongolia 74 BMP8B 32039173 Front Bioeng Biotechnol 2020 PMC6992545 10.3389/fbioe.2019.00455 0 0 0 137 Nutrigenomics|Supercritical Fluid Extraction|Metabolomics|Obesity|Proteomics|Diet|Nutritional Status|Genomics|Risk Factors|Cancer|Microbiome, Gut|Plant Extracts 74 BMP8B 32000663 BMC Genomics 2020 PMC6993373 10.1186/s12864-020-6515-2 0 0 0 137 Female|Animals|Mice|*Transcriptome|CREB3 protein, human|*Cyclic AMP Response Element-Binding Protein|*Stromal Cells|Decidua|Cell Proliferation|RNA, Small Interfering|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|*Epithelial Cells|Creb3 protein, mouse 74 BMPER 32468615 J. Cell. Physiol. 2020 10.1002/jcp.29829 0 0 0 173 Mice|Animals|*Adipocytes|*Bone Morphogenetic Proteins|*Pericardium|*Obesity|Adipose Tissue|*Upregulation|Visceral Fat|Diet, High-Fat|Mice, Obese|*Precursor Cells, B-Lymphoid|Endothelial Cell|Signal Transduction|Cell Differentiation|Mesenchymal Stem Cells|Cells, Cultured|Free Fatty Acids|*Transcriptional Activation|Apoptosis 86 BMPER 32432046 Front Oncol 2020 PMC7214627 10.3389/fonc.2020.00711 0 0 0 173 Humans|*Glioma|*Magnetic Resonance Imaging|Brain Neoplasms|*Neovascularization, Pathologic|Neoplasm Grading|Perfusion Imaging|*Biomarkers|CXCL10 protein, human|Chemokine CXCL10|BMPER protein, human|Carrier Proteins 86 BMPER 32309430 Biomed Res Int 2020 PMC7136775 10.1155/2020/3607436 0 0 0 173 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|Cell Movement|Cell Line, Tumor|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Apoptosis|Autophagy|*Cell Count|BMPER protein, human|Carrier Proteins 86 BMPER 32096002 Cardiovasc Drugs Ther 2020 10.1007/s10557-020-06939-5 0 0 0 173 *Hydrogen Peroxide|*Vardenafil Dihydrochloride|*Cyclic Nucleotide Phosphodiesterases, Type 5|*Signal Transduction|Oxidative Stress|Human Umbilical Vein Endothelial Cells|Apoptosis|Protective Agents|Cells, Cultured|*Phosphodiesterase 5 Inhibitors 86 bnc1 32486296 Int J Mol Sci 2020 PMC7312458 10.3390/ijms21113940 0 0 0 179 *Edetic Acid|*Periplasm|Periplasmic Binding Proteins|Protein Conformation|ATP-Binding Cassette Transporters|Crystallography, X-Ray|Models, Molecular|Chelating Agents|*Biophysical Phenomena 94 bnc1 32360590 Biochim Biophys Acta Mol Basis Dis 2020 10.1016/j.bbadis.2020.165822 0 0 0 179 *Transcriptome|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Machine Learning|*Algorithms|Machine, Support Vector|Lung Adenocarcinoma|Carcinoma, Squamous Cell|Gene Expression Profiling|Monte Carlo Method 94 bnc1 32099950 J Endocr Soc 2020 PMC7033037 10.1210/jendso/bvz037 0 0 0 179 Humans|Female|Animals|*Primary Ovarian Insufficiency|*Menopause, Premature|*Sequencing, Next-Generation|Amenorrhea|Whole Exome Sequencing|Infertility 94 BNC2 32629302 Aquat. Toxicol. 2020 10.1016/j.aquatox.2020.105525 0 0 0 85 Animals|*Zebrafish|*Disinfection|Zebrafish Proteins|Embryo, Nonmammalian|Halogenation|Disinfectants|Melanophores|Water Purification|*Hypopigmentation|Dilution, Pigmentary|*Albinism, Oculocutaneous|*Iodides|Water Pollutants, Chemical|Gene Expression Regulation, Developmental 77 BNC2 32387914 Forensic Sci Int Genet 2020 10.1016/j.fsigen.2020.102301 0 0 0 85 Humans|Eye Color|*Phenotype|Forensic Genetics|Hair Color|Genotype|*Pigmentation|Massively Parallel Sequencing|Markers, DNA|DNA|Skeletal Remains|Polymerase Chain Reaction|Polymorphism, Single Nucleotide|*Bone|*Pigmentation Disorders 77 BNC2 32272554 Cancers (Basel) 2020 PMC7226056 10.3390/cancers12040892 0 0 0 85 Humans|*Glioma|*RNA-Binding Proteins|Gene Ontology Project|Glioblastoma|Brain Neoplasms|Protein Interaction Maps|RNA|Gene Regulatory Networks|Gene Expression Profiling|Computational Biology|Sequencing, RNA|Gene Expression Regulation, Neoplastic|Transcriptome|Genome 77 BNC2 32030084 Curr. Genomics 2020 PMC6983957 10.2174/1389202920666190730132411 0 0 0 85 Humans|Adolescent|*Scoliosis|*Kyphosis|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genetic Association Studies|Homeodomain Proteins|Transcription Factors|Genotype|Case-Control Studies 77 BRAC1 32356124 J. Assist. Reprod. Genet. 2020 PMC7311593 10.1007/s10815-020-01783-w 0 0 0 0 Humans|Female|*Genes, BRCA2|BRCA1 protein, human|*BRCA1 Protein|Genes, BRCA1|BRCA2 Protein|*Carcinoma, Ovarian Epithelial|Germ-Line Mutation|Ovarian Neoplasms|Genetic Predisposition to Disease|Mutation|Pedigree|China|BRCA2 protein, human 40 BRAC1 32277283 Med. Oncol. 2020 10.1007/s12032-020-01371-z 0 0 0 0 Humans|Female|*Topoisomerase II|Breast Cancer, Familial|*Breast Carcinoma|BRCA1 protein, human|BRCA1 Protein|Topoisomerase II Inhibitors|Leukemia, Promyelocytic, Acute|Antineoplastic Agents|Mitoxantrone|Neoplasms, Second Primary|Ovarian Cancer|*Carcinoma, Ovarian Epithelial|Germ-Line Mutation|Translocation, Genetic 40 BRAC1 32121304 Int J Mol Sci 2020 PMC7084447 10.3390/ijms21051666 0 0 0 0 *Alzheimer Disease|Neurodegenerative Diseases|Neurofibrillary Tangles|Plaque, Amyloid|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|tau Proteins|*DNA Damage 40 brca1 32673153 J. Clin. Oncol. 2020 10.1200/JCO.19.02399 0 0 0 6364 Humans|Female|Pregnancy|Genes, BRCA2|Genes, BRCA1|Germ-Line Mutation|Mutation|*Germ Line 15461 brca1 32669374 Clin. Cancer Res. 2020 10.1158/1078-0432.CCR-20-1301 0 0 0 6364 Humans|veliparib|*5FU|*Oxaliplatin|*Benzimidazoles|*Pancreatic Cancer|BRCA1 protein, human|BRCA1 Protein|Genes, BRCA2|Genes, BRCA1|PARP Inhibitors|Germ-Line Mutation|Antineoplastic Combined Chemotherapy Protocols|Antineoplastic Agents|Mutation 15461 brca1 32669350 Cancer Res. 2020 10.1158/0008-5472.CAN-20-1451 0 0 0 6364 BRCA1 protein, human|BRCA1 Protein|BRCA2 protein, human|BRCA2 Protein|PARP Inhibitors|DNA Repair|Recombination Repair, Homologous|DNA Damage|Homologous Recombination|Synthetic Lethality|Antineoplastic Agents|Mutation|Cancer 15461 brca1 32668858 Gan To Kagaku Ryoho 2020 0 0 0 6364 Female|Humans|Adult|olaparib|Mastectomy|Neoplasm Recurrence, Local|*Phthalazines|*Piperazines|Paclitaxel|Antineoplastic Combined Chemotherapy Protocols|Lymph Nodes|BRCA1 protein, human|BRCA1 Protein|Bevacizumab|Adjuvant Chemotherapy|Lymphatic Metastasis|Combined Modality Therapy|Triple-Negative Breast Cancer|Antibodies, Monoclonal, Humanized|*Relapse|*HIV Infection 15461 brca1 32665703 Genet. Med. 2020 10.1038/s41436-020-0862-x 0 0 0 6364 Humans|Female|*Carcinoma, Ovarian Epithelial|BRCA2 protein, human|*BRCA2 Protein|BRCA1 protein, human|*BRCA1 Protein|*Heterozygote|Genes, BRCA2|Genes, BRCA1|*Ovarian Neoplasms|*Multifactorial Inheritance|Genetic Predisposition to Disease|Receptors, Estrogen|Polymorphism, Single Nucleotide|Mutation|Risk Factors 15461 brca1 32658311 Int. J. Cancer 2020 10.1002/ijc.33199 0 0 0 6364 Humans|Aged|PALB2 protein, human|Fanconi Anemia Complementation Group N Protein|CHEK2 protein, human|Checkpoint Kinase 2|*Colorectal Cancer|BRCA1 protein, human|BRCA1 Protein|Genetic Predisposition to Disease|Germ-Line Mutation|Genetic Testing|Case-Control Studies|*Germ Line 15461 brca1 32655836 Oncotarget 2020 PMC7335670 10.18632/oncotarget.27623 0 0 0 6364 Humans|*Triple-Negative Breast Cancer|IQ motif containing GTPase activating protein 1|*Centrosome|Cell Proliferation|BRCA1 protein, human|BRCA1 Protein|Signal Transduction|Cell Line, Tumor|Apoptosis|Phosphorylation 15461 brca1 32655641 J Oncol 2020 PMC7322604 10.1155/2020/9873954 0 0 0 6364 Humans|Female|*Heterozygote|Genes, BRCA2|Genes, BRCA1|BRCA2 Protein|BRCA1 Protein|Germ-Line Mutation|Genetic Testing|Genetic Predisposition to Disease|Ovarian Neoplasms|Mutation|*Germ Line 15461 brca1 32655639 J Oncol 2020 PMC7322596 10.1155/2020/6423936 0 0 0 6364 Female|Humans|olaparib|*Platinum|*Retrospective Studies|Cohort Studies|Croatia|Neoplasm Recurrence, Local|*Phthalazines|*Piperazines|*Carcinoma, Ovarian Epithelial|BRCA2 Protein|Poly(ADP-ribose) Polymerase Inhibitors|BRCA1 Protein|Genes, BRCA2|Ovarian Neoplasms|Genes, BRCA1|Maintenance Chemotherapy|Antineoplastic Agents|Progression-Free Survival 15461 brca1 32655299 Curr. Genomics 2020 PMC7324893 10.2174/1389202921666200210141701 0 0 0 6364 Humans|*RNA Splice Sites|RNA Splicing|Exons|Introns|Alternative Splicing|Mutations 15461 brca1 32653304 Semin. Cell Dev. Biol. 2020 10.1016/j.semcdb.2020.07.004 0 0 0 6364 *DNA Replication|*Homologous Recombination|MRE11 Homologue Protein|DNA Breaks, Double-Stranded|Rad51 Recombinase|BRCA2 Protein|DNA Repair|Genomic Instability|BRCA1 Protein|DNA-Binding Proteins|Recombination Repair, Homologous|Protein Binding|DNA 15461 brca1 32652823 Breast J 2020 10.1111/tbj.13970 0 0 0 6364 Female|Male|Humans|Mastectomy|Quality of Life|Lactation|Genes, BRCA2|Genes, BRCA1|BRCA2 protein, human|BRCA2 Protein|BRCA1 protein, human|BRCA1 Protein|Salpingo-oophorectomy|Heterozygote|Ovarian Cancer|Ovariectomy|*Risk|Mutations|Early Detection of Cancer 15461 brca1 32652753 Oncologist 2020 10.1634/theoncologist.2019-0609 0 0 0 6364 Humans|Female|*Crizotinib|*Protein-Tyrosine Kinases|*Proto-Oncogene Proteins|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Protein Kinase Inhibitors|Oncogene Proteins, Fusion|Drug Resistance, Neoplasm|Gene Rearrangement|*Ovarian Cancer|Mutations|Pyrazoles|Pyridines|Cell Line, Tumor|PARP Inhibitors|*Cystadenocarcinoma, Serous|ROS1 protein, human|GOPC protein, human 15461 brca1 32652442 Neoplasia 2020 PMC7350150 10.1016/j.neo.2020.06.009 0 0 0 6364 Mice|Animals|*Poly(ADP-ribose) Polymerase Inhibitors|olaparib|Phthalazines|PARP2 protein, human|Poly ADP Ribose Polymerase|Temozolomide|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|*Brain Tumors|*Antineoplastic Agents|Dacarbazine|Tumor Cell Lines|Antineoplastic Agents, Alkylating|BRCA1 protein, human|BRCA1 Protein|Piperazines|Xenograft Model Antitumor Assays|Drug Synergism 15461 brca1 32651552 Eur. 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Genet. 2020 10.1038/s41431-020-0692-y 0 0 0 6364 Humans|Female|*Carcinoma, Ovarian Epithelial|BRCA1 protein, human|*BRCA1 Protein|Genes, BRCA2|Genes, BRCA1|Ovarian Cancer|PARP Inhibitors|Genetic Counseling|Genetic Testing|Cystadenocarcinoma, Serous|Germ-Line Mutation|Genetic Predisposition to Disease|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|*Germ Line|England 15461 brca1 32651427 Sci Rep 2020 PMC7351787 10.1038/s41598-020-68224-7 0 0 0 6364 yin zhi huang|*Computational Biology|*Molecular Docking Simulation|*Drugs, Chinese Herbal|Medicine, Chinese Traditional|Signal Transduction|BRCA1 protein, human|BRCA1 Protein|*Hepatitis B|Genes, cdc 15461 brca1 32649346 Am J Dermatopathol 2020 10.1097/DAD.0000000000001719 0 0 0 6364 Female|Humans|Middle Aged|Nevus, Epithelioid and Spindle Cell|Skin Neoplasms|Nevus, Pigmented|BRCA1 protein, human|*BRCA1 Protein|Ubiquitin Thiolesterase|Melanoma|Melanocytes|Tumor Suppressor Proteins|Germ-Line Mutation|Mesothelioma, Malignant|Mesothelioma|Biomarkers, Tumor|*Synapsins|Nevus|Lung Neoplasms|BAP1 protein, human 15461 brca1 32648897 Essays Biochem. 2020 10.1042/EBC20200007 0 0 0 6364 TP53BP1 protein, human|Tumor Suppressor p53-Binding Protein 1|DNA Breaks, Double-Stranded|DNA End-Joining Repair|Homologous Recombination|DNA Repair|BRCA1 protein, human|BRCA1 Protein|RBBP8 protein, human|Nuclear Proteins|Exodeoxyribonucleases|G2 Phase|DNA, Single-Stranded|DNA-Binding Proteins|Carrier Proteins|Chromatin 15461 brca1 32643536 J. 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Sci. 2020 10.1242/jcs.241356 0 0 0 135 Humans|NFE2L2 protein, human|*NF-E2-Related Factor 2|EPHA5 protein, human|*Brain-Specific Kinase|*Gain of Function Mutation|Signal Transduction|MTOR protein, human|TOR Serine-Threonine Kinases|*Gene Expression Regulation|AMP-Activated Protein Kinases|Antioxidants|Brsk2 protein, human|Protein-Serine-Threonine Kinases 48 BRSK1 31895179 Menopause 2020 PMC7147414 10.1097/GME.0000000000001481 0 0 0 135 Humans|Female|*Menopause|Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Genotype|*Physical Activity|Age Factors|BRSK1 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins 48 BRWD3 32188026 Cancers (Basel) 2020 PMC7140059 10.3390/cancers12030700 0 0 0 50 Humans|Female|*miRNAs|*mRNA|*Papillomavirus Infections|Comparative Genomic Hybridization|Cervical Cancer|Cell Proliferation|Carcinogenesis|Keratinocyte|Cell Line, Tumor|Cell Cycle|BRWD3 protein, human|Transcription Factors|MIRN138 microRNA, human 25 BRWD3 32146388 Oral Oncol. 2020 10.1016/j.oraloncology.2020.104614 0 0 0 50 Humans|Male|Female|*Head and Neck Neoplasms|Head and Neck Squamous Cell Carcinoma|Papillomaviridae|Papillomavirus Infections|Carcinoma, Squamous Cell|Cell Line, Tumor|DNA Copy Number Variations|Cohort Studies 25 Bsx 32665445 J. 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Biol. 2020 10.1242/jeb.227330 0 0 0 24 Animals|*Appetite Regulation|*Fatty Acids|Rainbow Trout|mRNA|Neuropeptides|Oleate|Eating|*Brain 86 Bsx 32581684 Front Neurosci 2020 PMC7290237 10.3389/fnins.2020.00525 0 0 0 24 *Cell Differentiation|Agouti-Related Protein|Transcription Factor|Homeodomain Proteins|Hypothalamus|*Prosencephalon|Arcuate Nucleus of Hypothalamus|Nerve Tissue Proteins|Neuropeptide Y|Neurogenesis|Neurons|Gene Expression Regulation|Neuropeptides|Energy Metabolism 86 Bsx 32124219 Obes Surg 2020 10.1007/s11695-020-04514-3 0 0 0 24 Humans|*Non-alcoholic Fatty Liver Disease|*Bariatric Surgery|*Sleep Apnea, Obstructive|Polysomnography|Morbid Obesity|Hypoxia|Comorbidity|Severity of Illness Index 86 Bsx 32116574 Front Neuroanat 2020 PMC7016197 10.3389/fnana.2020.00003 2 0 0 24 Animals|*Zebrafish|*Hypothalamus|Embryo, Nonmammalian|Prosencephalon|Gene Expression Regulation, Developmental|Homeodomain Proteins|Neurons 86 Bsx 32056075 Obes Surg 2020 10.1007/s11695-020-04480-w 0 0 0 24 Humans|*Acute Pancreatitis|*Acute Disease|*Bariatric Surgery|Obesity, Morbid|Length of Stay|Retrospective Studies|Cohort Studies 86 BTBD9 32468214 Brain Struct Funct 2020 10.1007/s00429-020-02090-x 0 0 0 90 Mice|Animals|*Restless Legs Syndrome|*Mice, Knockout|*Dopamine|Nerve Tissue Proteins|Caenorhabditis elegans|Phenotypes|Dop-1 protein, C elegans|Receptors, Dopamine D1|Caenorhabditis elegans Proteins 67 BTBD9 32446853 Neuroscience 2020 PMC7363566 10.1016/j.neuroscience.2020.05.021 0 0 0 90 Humans|Mice|Animals|*Restless Legs Syndrome|Genome-Wide Association Study|*Mice, Knockout|*Cerebellum|Nerve Tissue Proteins|Transcription Factors|Sleep Disorder|Purkinje Cells|Polymorphism, Single Nucleotide|BTBD9 protein, human 67 BTBD9 32327643 Signal Transduct Target Ther 2020 PMC7181851 10.1038/s41392-020-0140-z 0 0 0 90 Humans|Proteomics|Ubiquitination|Ubiquitin|Cullin Proteins|Ubiquitin-Protein Ligases|Transcriptional Activation|Cytoplasm|TNFAIP1 protein, human|Proteins 67 BTBD9 31923196 PLoS ONE 2020 PMC6953832 10.1371/journal.pone.0226905 0 0 0 90 Animals|*Zebrafish|*MicroRNAs|Sequence Analysis, RNA|High-Throughput Nucleotide Sequencing|Gene Expression Profiling|Stress, Cold|Downregulation|Up-Regulation|Gene Library|Larva|Acclimatization|Fibroblast 67 BTG4 32558204 EMBO Rep. 2020 10.15252/embr.201949956 0 0 0 17 Mice|Female|Animals|*Zygotes|*mRNA Decay|mRNA, Maternal|Oocytes|Oogenesis|Meiosis|Cell Cycle Proteins|Embryonic Development|*Cytoplasm|mRNA|Gene Expression Regulation, Developmental|Mice, Knockout|Btg4 protein, mouse 40 BTG4 32502391 Am. 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Commun. 2020 10.1016/j.bbrc.2020.04.148 0 0 0 110 Mice|Animals|*Ventricular Remodeling|Reproducibility of Results|*Receptors, Adrenergic, beta|Heart Failure|Isoproterenol|Myocardium|*Receptors, Adrenergic, beta-2|Myocytes, Cardiac|Fibrosis|Left Ventricular Function|Mice, Knockout|Apoptosis 33 C1QTNF6 32282241 DNA Cell Biol. 2020 10.1089/dna.2019.5299 0 0 0 110 Humans|Clear Cell Renal Cell Carcinoma|Kidney Neoplasms|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Neoplasm Staging|Kaplan-Meier Estimate|Disease Progression|Cell Proliferation|Cell Line, Tumor|Computational Biology 33 C1QTNF6 32061050 Pediatr Diabetes 2020 10.1111/pedi.12995 0 0 0 110 *Diabetes Mellitus, Type 1|*Autoimmunity|*DNA Methylation|*B-DNA|Insulin|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Autoantibodies 33 C1QTNF6 31955152 Aging (Albany NY) 2020 PMC7053628 10.18632/aging.102672 0 0 0 110 Humans|*AMP-Activated Protein Kinases|*Particulate Matter|miRNA|RNA, Long Noncoding|Signal Transduction|Apoptosis|Cell Line, Tumor|Luciferase|C1qTNF6 protein, human|Collagen 33 C1QTNF9B 32481463 Medicine (Baltimore) 2020 10.1097/MD.0000000000020494 0 0 0 1 Humans|*Coronary Artery Disease|*Selenium|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Asian Continental Ancestry Group|Adiponectin|Genotype|Risk Factors|Case-Control Studies|Ethnic Groups|China|CYP4F2 protein, human|Cytochrome P450 Family 4 38 C1QTNF9B 31945100 PLoS ONE 2020 PMC6964899 10.1371/journal.pone.0226526 0 0 0 1 *Kidney Transplantation|Adiponectin|TYRP1 protein, human|*Membrane Glycoproteins|*Transplantation, Homologous|TNF protein, human|*Tumor Necrosis Factor-alpha|*Kidney|Atherosclerosis|*Lymphotoxin-alpha|Cardiovascular Disease|Risk Factors 38 C5orf42 32367316 Mol. 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Neurosci. 2020 10.1002/jdn.10029 0 0 0 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Heterozygote|*Mutations|DNA Mutational Analysis|Phenotype|Pedigree|Membrane Proteins|Whole Exome Sequencing|Neuroimaging|Magnetic Resonance Imaging|C5orf42 protein, human 24 CALB2 32675174 eNeuro 2020 10.1523/ENEURO.0179-20.2020 0 0 0 555 Animals|*Spiral Ganglion|*Neurons|Inner Hair Cells|Cochlea|*Receptors, Purinergic|P2RY2 protein, human|*Receptors, Purinergic P2Y2 1236 CALB2 32634123 JCI Insight 2020 10.1172/jci.insight.138290 0 0 0 555 *Proteome|Proteomics|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Neoplasm Proteins|Adenocarcinoma|Stromal Cells|Cell Line, Tumor|Laser Capture Microdissection|Extracellular Matrix|Cohort Studies 1236 CALB2 32565162 Cell. Signal. 2020 10.1016/j.cellsig.2020.109695 0 0 0 555 Humans|*RNA, Long Noncoding|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|*Odontoblasts|*Dental Pulp|*Cell Differentiation|*Up-Regulation|MicroRNAs|Odontogenesis|Stem Cells|DMP1 protein, human|Extracellular Matrix Proteins|*Transcriptional Activation|Phosphoproteins|Cells, Cultured|Downregulation|mRNA 1236 CALB2 32533757 Mol Oncol 2020 10.1002/1878-0261.12749 0 0 0 555 Humans|Female|*Cell Adhesion|*Up-Regulation|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|Cystadenocarcinoma, Serous|Peritoneal Neoplasms|Ascites|Mesothelium|Cadherins|Peritoneal Fluid|Extracellular Matrix|Cell Line, Tumor|*Transcriptional Activation|Spheroids, Cellular|CALB2 protein, human|Calretinin 1236 CALB2 32420617 J. Comp. Neurol. 2020 10.1002/cne.24952 0 0 0 555 Mice|Animals|*Lac Operon|*Transcription Factors|Homeodomain Proteins|Transgenic Mouse|Gene Expression Regulation, Developmental|In Situ Hybridization|Cell Migration|Dlx5 protein, mouse 1236 CALHM1 32497506 Neuron 2020 10.1016/j.neuron.2020.05.012 0 0 0 64 *Taste|Taste Buds|Amiloride|Calcium Channels|*Dysgeusia|*Calcium, Dietary|Sodium Chloride|Signal Transduction|Sodium Channel, Epithelial|Homeostasis|*Minerals 84 CALHM1 32374262 Elife 2020 PMC7242029 10.7554/eLife.55853 0 0 0 64 Humans|Pregnancy|Female|*Calcium Channels|*Cryoelectron Microscopy|*Homeostasis|Models, Molecular|Placenta|CALHM1 protein, human|Membrane Glycoproteins 84 CALHM1 32229307 Neuron 2020 10.1016/j.neuron.2020.03.006 1 0 0 64 Taste Buds|Taste|Sodium|Calcium Channels|Epithelial Amiloride-Sensitive Sodium Channel|Amiloride|*Burkitt Lymphoma 84 CALHM1 32182953 Cells 2020 PMC7140682 10.3390/cells9030664 0 0 0 64 *Glucose|*Oxygen|*Neuroprotection|*Hippocampus|Neuroprotective Agents|Cell Death|Calcium Channel|Neurons|Cell Survival|Organ Culture Techniques|Cells, Cultured|Cytosol 84 CALHM1 31988524 Nat. 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Toxicol. 2020 10.1002/jbt.22480 0 0 0 147 96 CASC2 32016985 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202001_20063 0 0 0 147 Humans|*Mesangial Cells|*RNA, Long Noncoding|*Oxidative Stress|*Extracellular Matrix|*Transcription Factors|Diabetic Nephropathy|MicroRNAs|Reactive Oxygen Species|Cell Proliferation|Glucose|Cells, Cultured|FOXP1 protein, human|Repressor Proteins|Forkhead Transcription Factors|CASC2 protein, human|Tumor Suppressor Proteins 96 CASC2 32009793 Onco Targets Ther 2020 PMC6859698 10.2147/OTT.S235046 0 0 0 147 *RNA, Long Noncoding|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*Apoptosis Regulatory Proteins|MicroRNAs|Gene Expression Regulation, Neoplastic|Carcinoma, Hepatocellular|Liver Neoplasms|Cell Proliferation|Cell Movement|Down-Regulation|Tumor Suppressor Proteins|Cell Line, Tumor 96 CASC2 31958564 J. Chem. 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Res. 2020 PMC6954528 10.1186/s12931-019-1257-x 0 0 0 147 *RNA, Long Noncoding|RNA, Micro|mRNA|Prognosis|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Ontology|Kaplan-Meier Estimate|*Asthma 96 CASC2 31903804 Expert Rev Respir Med 2020 10.1080/17476348.2020.1711736 0 0 0 147 96 CASC2 31894271 Int. J. Oncol. 2020 PMC6959463 10.3892/ijo.2019.4937 0 0 0 147 *RNA, Long Noncoding|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Disease Progression|Downregulation|Upregulation|Cell Movement|Tumor Suppressor Proteins|Cell Line, Tumor|Apoptosis|Tumorigenesis|*Cell Transformation, Neoplastic|Pancreatic Cancer 96 CASP5 32311223 Cancer Med 2020 PMC7300420 10.1002/cam4.2983 1 0 0 94 Humans|*Carcinoma, Renal Cell|*Prognosis|Kidney Neoplasms|Biomarkers, Tumor|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|Neoplasm Staging|Transcriptome Profiles|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Receiver Operating Characteristic|*Algorithm|*Cell Microenvironment|Cohort Studies 152 CASZ1 32071204 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7060670 10.1073/pnas.1918628117 0 0 0 1001 *Retina|*Neurogenesis|Amacrine Cells|Retinal Horizontal Cells|Homeodomain Proteins|Cell Differentiation|Gene Expression Regulation, Developmental|Eye Proteins|Glia|Forkhead Transcription Factors 61 CASZ1 32060262 Nat Commun 2020 PMC7021771 10.1038/s41467-020-14684-4 0 0 0 1001 Factor, MyoD|Myogenin|Myoblasts|Myogenesis|*Muscle, Skeletal|Transcription Factor|Cell Differentiation|DNA-Binding Proteins|Chromatin|Embryonal Rhabdomyosarcoma|Tumorigenesis|Up-Regulation|Cell Transformation, Neoplastic|Cell Proliferation|Signal Transduction|Transcriptional Activation|Gene Expression Regulation, Neoplastic 61 CCBE1 32629717 Medicine (Baltimore) 2020 PMC7337536 10.1097/MD.0000000000020995 0 0 0 132 Humans|Female|Infant|*Lymphangiectasis, Intestinal|Enteropathy, Protein-Losing|*Syndrome|Lymphedema|*Mutation|Intestines|CCBE1 protein, human|Calcium-Binding Proteins|Tumor Suppressor Proteins 69 CCBE1 32600346 BMC Pregnancy Childbirth 2020 PMC7325062 10.1186/s12884-020-03073-w 0 0 0 132 Pregnancy|Female|Humans|*Lymphatic Vessels|Lymphatic Endothelial Cell|Biomarkers|Membrane Glycoproteins|*Placenta|Transcription Factors 69 CCBE1 32483144 Nat Commun 2020 PMC7264274 10.1038/s41467-020-16552-7 0 0 0 132 Animals|*Lymphangiogenesis|*Zebrafish|*Vascular Endothelial Growth Factor C|Zebrafish Proteins|Lymphatic Vessels|Vascular Endothelial Growth Factor Receptor-3|Gene Expression Regulation, Developmental|Calcium-Binding Proteins|*Fibroblast|Signal Transduction 69 CCBE1 32472549 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.06.018 0 0 0 132 Humans|Child|Hennekam lymphangiectasia lymphedema syndrome|*Lymphangiectasis, Intestinal|*Craniofacial Abnormalities|*Lymphedema|Genotype|Alleles|Calcium-Binding Proteins|Mutation|Tumor Suppressor Proteins|CCBE1 protein, human 69 CCBE1 32397815 DNA Cell Biol. 2020 10.1089/dna.2019.5313 0 0 0 132 Humans|Female|RNA, Long Noncoding|Prognosis|Gene Expression Regulation, Neoplastic|*Carcinoma, Endometrioid|Endometrial Neoplasms|Biomarkers, Tumor|Sequencing, RNA|Gene Expression Profiling|Kaplan-Meier Estimate|Transcriptome|DNA Methylation|Databases, Genetic|Nomogram|Receiver Operating Characteristic|Cohort Studies 69 CCBE1 32379844 PLoS ONE 2020 PMC7205231 10.1371/journal.pone.0232542 0 0 0 132 Humans|Swine|Animals|*Hernia, Umbilical|*Transcriptome Analysis|Genome-Wide Association Study|SNPs|Transcriptome|Swine Diseases|DNA Copy Number Variations|Sequencing, RNA|CCBE1 protein, human|Calcium-Binding Proteins|Tumor Suppressor Proteins 69 CCBE1 32182215 J. Clin. Invest. 2020 PMC7260025 10.1172/JCI99027 1 0 0 132 Humans|Lymphangiogenesis|VEGF-C|Lymphatic Vessel|*Cadherins|*Lymphatic Endothelial Cell|Vascular Endothelial Growth Factor Receptor-3|Lymphangiectasis, Intestinal|Lymphedema|Procollagen N-Endopeptidase|ADAMTS Proteins|Signal Transduction|Tumor Suppressor Proteins|Phenotype|Calcium-Binding Proteins|Mutations|Amino Acid Substitution|HEK293 Cells|ADAMTS3 protein, human 69 CCBE1 32089745 Theranostics 2020 PMC7019157 10.7150/thno.39740 0 0 0 132 Humans|*Lymphangiogenesis|Vascular Endothelial Growth Factor C|*Colorectal Cancer|Lymphatic Vessels|Vascular Endothelial Growth Factor Receptor-3|*Signal Transduction|Tumor Suppressor Proteins|*Collagen Type I|Endothelial Cells|Calcium-Binding Proteins|*Colonic Neoplasms|*Protein Domains|HEK293 Cells|CCBE1 protein, human 69 CCBE1 31911667 Nat Commun 2020 PMC6946812 10.1038/s41467-019-14003-6 1 0 0 132 Female|Humans|*Osteoclasts|*Osteoblast|*Bone|Bone Remodeling|Osteogenesis|Bone Resorption|RANK Ligand|*Energy Metabolism|Glucagon-Like Peptide 1|CCBE1 protein, human|Calcium-Binding Proteins|Tumor Suppressor Proteins 69 CCDC170 32321829 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7211963 10.1073/pnas.1921333117 0 0 0 50 22 CCDC88A 32627003 Mol Med Rep 2020 PMC7339712 10.3892/mmr.2020.11240 0 0 0 649 Humans|*Gossypol|*Interleukin-8|Triple Negative Breast Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|European Continental Ancestry Group|Apoptosis|Cell Line, Tumor|Signal Transduction|African Americans|Proto-Oncogene Proteins c-akt|Cell Movement|Upregulation|Gene Expression|Transcriptional Activation|CCL2 protein, human|Chemokine CCL2|CCDC88A protein, human 131 CCDC88A 32307399 Biomed. Res. 2020 10.2220/biomedres.41.113 0 0 0 649 Humans|Child|Double-Blind Method|*Duodenum|Duodenitis|Intestinal Mucosa|Duodenal Ulcer|*Intestinal Diseases|Intestine|Celiac Disease|Phosphorylation|CCDC88A protein, human|Microfilament Proteins|Vesicular Transport Proteins 131 CCL14 32413576 J Ethnopharmacol 2020 10.1016/j.jep.2020.112964 0 0 0 47 Humans|*Ginkgo biloba|*Proteomics|*Meglumine|Ginkgolides|Ginkgo biloba extract|*Plant Extracts|*Diterpenes|*Acute Stroke|*Lactones|Anti-Inflammatory Agents|Neuroprotective Agents|Drugs, Chinese Herbal|*Biomarkers|*Injection 77 CCL14 32322603 Open Forum Infect Dis 2020 PMC7162619 10.1093/ofid/ofaa099 0 0 0 47 Male|Humans|*HIV Infections|*Anti-Retroviral Agents|CD4 Lymphocyte Count|Anti-HIV Agents|*Biomarkers|*Inflammation|Viral Load|*Patient Compliance 77 CCL14 32218842 Oncol Lett 2020 PMC7068588 10.3892/ol.2020.11378 0 0 0 47 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|*Prognosis|Neoplasms, Glandular and Epithelial|Cytoreduction Surgical Procedures|Biomarkers, Tumor|Kaplan-Meier Estimate|*Chemokines|Disease Progression|China 77 CCL14 32025755 Intensive Care Med 2020 PMC7210248 10.1007/s00134-019-05919-0 1 0 0 47 *Acute Kidney Injury|Lipocalin-2|*Biomarkers|Lipocalins|Acute-Phase Proteins|ROC Curve|Creatinine|Kidney|Prospective Studies 77 CCL14 31991604 Cancers (Basel) 2020 PMC7072521 10.3390/cancers12020287 4 0 0 47 Humans|*Prognosis|*Cancer|*Neoplastic Processes|Tumor Microenvironment|Immunotherapy|CXCL12 protein, human|Chemokine CXCL12|CX3CL1 protein, human|Chemokine CX3CL1|Chemokines, CC|Neovascularization, Pathologic|Disease Progression|Inflammation 77 CCL14 31927532 Aging (Albany NY) 2020 PMC6977663 10.18632/aging.102656 0 0 0 47 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Prognosis|Neoplasm Recurrence, Local|*Chemokines|Lymphocytes, Tumor-Infiltrating|Hepatitis A Virus Cellular Receptor 2|Kaplan-Meier Estimate|CD8-Positive T-Lymphocytes|Gene Expression Profiling|desintegron B|*Betaine|Macrophages|*Ligands|Biomarkers|CCL14 protein, human|Chemokines, CC 77 CCL14 31909895 Anat Rec (Hoboken) 2020 10.1002/ar.24353 0 0 0 47 Humans|*Medicine, Chinese Traditional|*Syndrome|PCSK9 protein, human|*Proprotein Convertase 9|Tandem Mass Spectrometry|*Tuberculosis, Multi Drug Resistant|Yin Deficiency|*Biomarkers|*Immunoglobulin G|Chromatography, Liquid|*Ligands|betaIG-H3 protein|*Transforming Growth Factor beta|*Chemokines|Proteomics|Bioinformatics|Receiver Operating Characteristic|Extracellular Matrix Proteins 77 CCL15 32066664 Transl Psychiatry 2020 PMC7026448 10.1038/s41398-020-0693-1 0 0 0 148 Humans|*Stress Disorders, Post-Traumatic|*Military Personnel|Case-Control Studies|Combat Disorders|Iraq War, 2003-2011|Afghan Campaign 2001-|Risk Factors|*Chemokines|*Biomarkers|Afghanistan|Iraq 118 CCL18 32655851 Ther Adv Endocrinol Metab 2020 PMC7331767 10.1177/2042018820930902 0 0 0 598 *Insulin Resistance|*Obesity|*Adipose Tissue|CXCL11 protein, human|*Chemokine CXCL11|*Inflammation|CXCL9 protein, human|Chemokine CXCL9|*Biomarkers|*Gene Expression|Adipose Tissue, Subcutaneous|*Biochemical Phenomena 568 CCL18 32641093 BMC Cancer 2020 PMC7346480 10.1186/s12885-020-07073-z 0 0 0 598 Oral Cancer|Carcinoma, Squamous Cell|JAK2 protein, human|*Janus Kinase 2|CCL18 protein, human|*Chemokines, CC|*Signal Transduction|Neoplasm Invasiveness|Epithelial-Mesenchymal Transition|*Neoplastic Processes|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Cell Transformation, Neoplastic 568 CCL18 32630441 J Clin Med 2020 10.3390/jcm9061993 0 0 0 598 *Idiopathic Pulmonary Fibrosis|CCL18 protein, human|*Chemokines, CC|Case-Control Studies|*Research Design|Genetic Variation 568 CCL18 32603741 Int. J. Cardiol. 2020 10.1016/j.ijcard.2020.06.030 0 0 0 598 Humans|*Atrial Fibrillation|*Prognosis|Cohort Studies|Stroke|Anticoagulants|Risk Assessment|Risk Factors|Follow-Up Studies|*Chemokines 568 CCL18 32575869 J Clin Med 2020 10.3390/jcm9061940 0 0 0 598 *Idiopathic Pulmonary Fibrosis|CCL18 protein, human|*Chemokines, CC|Single Nucleotide Polymorphisms|Lung|Case-Control Studies|Fibroblasts|Extracellular Matrix 568 CCL18 32562787 Biochem. Pharmacol. 2020 10.1016/j.bcp.2020.114103 0 0 0 598 Humans|Mice|Animals|*Kinase Inhibitors, Janus|*Macrophages|*Anti-Inflammatory Agents|JAK1 protein, human|Janus Kinase 1|JAK2 protein, human|Janus Kinase 2|JAK3 protein, human|Janus Kinase 3|Janus Kinases|tofacitinib|Pyrimidines|*Interstitial Lung Disease|Pyrroles|Protein Kinase Inhibitors|Piperidines|Cytokines|INCB018424 568 CCL18 32548267 Sci Adv 2020 PMC7274799 10.1126/sciadv.aba4376 0 0 0 598 Humans|Mice|Animals|IL4 protein, human|*Interleukin-4|*Colitis|*Macrophages|Dextran Sulfate|Inflammatory Bowel Disease|*Wound Healing|*Disease Models, Animal|Intestinal Mucosa|Monocytes|Epithelial Cells 568 CCL18 32487604 Anticancer Res. 2020 10.21873/anticanres.14291 0 0 0 598 Humans|*Oestradiol|Receptors, Estrogen|*Estrogens|Signal Transduction|*Ligands|Receptors, G-Protein-Coupled|MCF-7 Cells|ErbB Receptors|*Chemokines|Cell Proliferation|Cell Line, Tumor|Pathway, ERK|CCL18 protein, human|Chemokines, CC 568 CCL18 32471866 J. Biol. Chem. 2020 10.1074/jbc.RA120.014103 0 0 0 598 Animals|*Chemokines|peptide B|Receptors, Chemokine|CCL18 protein, human|Chemokines, CC|Protein Binding|Amino Acid Sequence|Ligands|Chemotaxis|Ticks|Cell Movement|Inflammation 568 CCL18 32413576 J Ethnopharmacol 2020 10.1016/j.jep.2020.112964 0 0 0 598 Humans|*Ginkgo biloba|*Proteomics|*Meglumine|Ginkgolides|Ginkgo biloba extract|*Plant Extracts|*Diterpenes|*Acute Stroke|*Lactones|Anti-Inflammatory Agents|Neuroprotective Agents|Drugs, Chinese Herbal|*Biomarkers|*Injection 568 CCL18 32404914 Sci Rep 2020 PMC7220941 10.1038/s41598-020-64431-4 0 0 0 598 *Transcriptome|*Synovial Membrane|*Rheumatoid Arthritis|Fluid, Synovial|*Macrophages|Osteoarthritis|Monocytes|CCL18 protein, human|Chemokines, CC|Fibroblasts|Calgranulin A 568 CCL18 32384128 PLoS ONE 2020 PMC7209254 10.1371/journal.pone.0232978 0 0 0 598 Humans|*Interstitial Lung Disease|*Rheumatoid Arthritis|Lung|Mucin-1|Vital Capacity|Biomarkers|Disease Progression|Tomography, X-Ray Computed 568 CCL18 32374474 J. Cell. Mol. Med. 2020 PMC7267175 10.1111/jcmm.15360 0 0 0 598 Humans|silvestrol|COVID-19|severe acute respiratory syndrome coronavirus 2|*Antiviral Agents|*Triterpenes|Virus Replication|*Monocyte-Derived Macrophages|Chikungunya virus|Zika Virus|Ebola Virus|Zika Virus Infection|Cytokines|Hemorrhagic Fever, Ebola|Dendritic Cells|TREM2 protein, human|Membrane Glycoproteins|Receptors, Immunologic 568 CCL18 32319143 Mol. Carcinog. 2020 10.1002/mc.23201 0 0 0 598 Humans|Male|lactate dehydrogenase 1|L-Lactate Dehydrogenase|*Prostate Cancer|Cell Line, Tumor|Isoenzymes|CCL18 protein, human|Chemokines, CC|Gene Expression Regulation, Neoplastic|Glycolysis|Downregulation|Cell Proliferation|Lactate|Disease Progression|Prognosis|Upregulation|CCR8 protein, human|Receptors, CCR8|ARNT protein, human 568 CCL18 32280674 Biomed Res Int 2020 PMC7115052 10.1155/2020/1497175 0 0 0 598 Humans|*Dermatitis, Atopic|TLR2 protein, human|*Toll-Like Receptor 2|*Leukocytes, Mononuclear|*Chemokines|*Eczema|Chemokine CCL17|Skin|Chemokine CCL22|*Leukocytes|*Mononuclear Phagocyte System|RNA, Messenger 568 CCL18 32202908 Neoplasma 2020 10.4149/neo_2020_190821N802 0 0 0 598 Humans|Male|*Carcinoma, Squamous Cell|*Mouth Neoplasms|Neoplasm Recurrence, Local|Lymphatic Metastasis|Prognosis|CCL18 protein, human|*Chemokines, CC|Immunohistochemistry|Disease-Free Survival|Biomarkers, Tumor|mRNA 568 CCL18 32126008 Clin. Chem. Lab. Med. 2020 10.1515/cclm-2019-0949 0 0 0 598 Humans|sphingosyl beta-glucoside|*Gaucher Disease|*Chromatography, Liquid|Retrospective Studies|*Tandem Mass Spectrometry|*Follow-Up Studies|*Psychosine|chitotriosidase|Hexosaminidases|*Biomarkers|CCL18 protein, human|Chemokines, CC|*Plasma|Specificity|Chitinases 568 CCL18 32089354 Semin. Arthritis Rheum. 2020 10.1016/j.semarthrit.2020.01.006 1 0 0 598 *Interstitial Lung Diseases|*Idiopathic Pulmonary Fibrosis|*Connective Tissue Diseases|*Biomarkers|*Pulmonary Circulation|CCL18 protein, human|Chemokines, CC|Matrix Metalloproteinase 7|Tomography, X-Ray Computed 568 CCL18 32039442 Biosci. Rep. 2020 PMC7040463 10.1042/BSR20193101 0 0 0 598 *Nasal Polyps|*Sinusitis|Rhinitis|Eosinophilia|*Chronic Disease|Cytokines|Th2 Cell|Asthma|CCL24 protein, human|Eotaxin 2|Bioinformatics 568 CCL18 32012488 Mol Genet Genomic Med 2020 PMC7196483 10.1002/mgg3.1159 1 0 0 598 *Carcinoma, Renal Cell|*Prognosis|Kidney Neoplasms|Bioinformatics|Gene Regulatory Networks|Protein Interaction Maps|*Carcinoma|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Tumor Microenvironment|*Databases, Factual|Kaplan-Meier Estimate|*Cell Microenvironment 568 CCL7 32659965 Int J Mol Sci 2020 10.3390/ijms21144855 0 0 0 605 titanium dioxide|Titanium|Particle Size|Nanoparticles|Lung 784 CCL7 32657004 Aging Cell 2020 10.1111/acel.13170 0 0 0 605 Mice|Animals|*Ectromelia virus|*Innate Immune Response|*Mice, Inbred C57BL|*Ectromelia, Infectious|Natural Killer Cells|Monocytes|Interferon-gamma|Dendritic Cells|CXCL9 protein, human|Chemokine CXCL9|Lymph Nodes 784 CCL7 32649507 Chin. Med. J. 2020 10.1097/CM9.0000000000000915 0 0 0 605 Mice|Animals|*Diet, High-Fat|*Obesity|*Intestines|Non-alcoholic Fatty Liver Disease|Insulin Resistance|Liver|Gastrointestinal Microbiome|*Chemokines|*Protective Agents 784 CCL7 32629323 Mol. Immunol. 2020 10.1016/j.molimm.2020.06.027 0 0 0 605 Mice|Animals|*Th17 Cells|*Up-Regulation|RNA, Long Noncoding|MicroRNAs|Gene Expression Regulation, Neoplastic|IL17A protein, human|IL-17A|Encephalomyelitis, Autoimmune, Experimental|Cell Differentiation|Cell Movement|Cell Proliferation|*Transcriptional Activation|Disease Progression|Multiple Sclerosis|Ccl7 protein, mouse|Chemokine CCL7 784 CCL7 32616889 Oncogene 2020 10.1038/s41388-020-1378-1 0 0 0 605 Humans|*Stomach Neoplasms|MCAM protein, human|*CD146 Antigen|Neoplasm Recurrence, Local|Cell Movement|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Chemokines|Up-Regulation|Cell Line, Tumor|Transcription Factor|CCL7 protein, human|Chemokine CCL7|SOX18 protein, human|SOXF Transcription Factors 784 CCL7 32562599 Immunity 2020 10.1016/j.immuni.2020.06.008 0 0 0 605 *Macrophages|*Spleen|CSF1 protein, human|Colony-Stimulating Factor 1|HNF1A protein, human|*Hepatocyte Nuclear Factor 1-alpha|*Gene Expression Regulation|*Fibroblasts|Red Blood Cells|Iron|*Wilms Tumor|Homeostasis|*Maintenance|*Leukocyte Count|Kidney Neoplasms 784 CCL7 32508810 Front Immunol 2020 PMC7248379 10.3389/fimmu.2020.00800 0 0 0 605 Humans|Mice|Animals|*Down-Regulation|Endothelial Cells|Proto-Oncogene Protein c-fli-1|Fibroblasts|Fibrosis|Skin|Epigenesis, Genetic|*Scleroderma, Localized|Cells, Cultured|Macrophages|*Myeloid Cells|Disease Models, Animal 784 CCL7 32488176 Sci Rep 2020 PMC7265460 10.1038/s41598-020-65998-8 0 0 0 605 Mice|Animals|*Microglia|*Lipopolysaccharides|*Anti-Inflammatory Agents|Neuroprotective Effects|Inflammation|Cytokines|Hybrid-B|*Plasminogen Activators|Macrophages|Neuroprotection|Cell Line|Signal Transduction|Gene Expression|*Phenotype 784 CCL7 32471866 J. Biol. Chem. 2020 10.1074/jbc.RA120.014103 0 0 0 605 Animals|*Chemokines|peptide B|Receptors, Chemokine|CCL18 protein, human|Chemokines, CC|Protein Binding|Amino Acid Sequence|Ligands|Chemotaxis|Ticks|Cell Movement|Inflammation 784 CCL7 32467242 Development 2020 PMC7328164 10.1242/dev.187815 0 0 0 605 Animals|Humans|Female|Sexual Maturation|*Macrophage|CCBP2 protein, human|CCR3 protein, human|*Receptors, CCR3|Morphogenesis|Mammary Glands, Animal|Chemokines|Signal Transduction|Epithelial Cells 784 CCL7 32452747 Cell Transplant 2020 10.1177/0963689720909387 0 0 0 605 Female|Humans|Rats|Animals|*Amniotic Fluid|*Rats, Sprague-Dawley|*Urinary Bladder|Stem Cell Transplantation|Stem Cells|NGF protein, human|Nerve Growth Factor|*Urologic Diseases|NGFR protein, human|Receptors, Nerve Growth Factor|Nerve Regeneration|*Pelvis|Disease Models, Animal|Receptor, Nerve Growth Factor|Growth Associated Protein 43|*B Cells 784 CCL7 32449695 Reproduction 2020 10.1530/REP-20-0100 0 0 0 605 Humans|Male|Animals|*Testis|Seminiferous Tubules|Spermatogenesis|Infertility, Male|AR protein, human|Androgen Receptor|ACTA2 protein, human|Actins|Proteome|*Proteomics|Common Marmoset|*B Cells|Cells, Cultured|*Protein Processing, Post-Translational 784 CCL7 32434555 Stem Cell Res Ther 2020 PMC7238576 10.1186/s13287-020-01706-7 0 0 0 605 Humans|Horses|Animals|*Mesenchymal Stem Cells|*Interleukin 1|*Bone Marrow|*Chondrogenesis|*Cell Differentiation|*Mass Spectrometry|Osteoarthritis 784 CCL7 32422289 Ann Vasc Surg 2020 10.1016/j.avsg.2020.04.047 0 0 0 605 Animals|*Stroke|*Brain Ischemia|*Upregulation|*Chemokines|Chemokine CCL2|Signal Transduction|Cytokines|*Transcriptional Activation|Neurons|Disease Models, Animal 784 CCL7 32402949 Int. Immunopharmacol. 2020 10.1016/j.intimp.2020.106540 0 0 0 605 Rats|Mice|Animals|*Maraviroc|TAK-652|*Rodents|*Rats, Wistar|*Pain, Neuropathic|*Imidazoles|CCR5 Receptor Antagonists|Ganglia, Dorsal Root|Receptors, CCR2|Hyperalgesia|Analgesics|Spinal Cord|Chemokine CCL2|Analgesics, Opioid|Nerve, Sciatic 784 CCL7 32377537 J Immunol Res 2020 PMC7191376 10.1155/2020/8074183 0 0 0 605 *Latent Tuberculosis|Tuberculosis|Interferon-gamma Release Tests|Mycobacterium tuberculosis|Antigens, Bacterial|Cytokines|ROC Curve|Case-Control Studies|Biomarkers|*Research Design|Diagnosis, Differential 784 CCL7 32376430 J. Am. Acad. Dermatol. 2020 10.1016/j.jaad.2020.04.138 0 0 0 605 Humans|*Alopecia Areata|*Cross-Sectional Studies|*Biomarkers|Dermatitis, Atopic|Th2 Cells|Th1 Cells|Inflammation|*Cardiovascular System|Severity of Illness Index 784 CCL7 32345237 BMC Cancer 2020 PMC7189470 10.1186/s12885-020-06868-4 0 0 0 605 Humans|Animals|Mice|*Disease Models, Animal|ERBB2 protein, human|*Receptor, ErbB-2|Trastuzumab|Antibodies, Monoclonal|Antibodies, Monoclonal, Humanized|Cell Line, Tumor|Antineoplastic Agents|Xenograft Model Antitumor Assays|Cell Proliferation|*Myeloid Progenitor Cells|Neovascularization, Pathologic|*Myeloid Cell 784 CCL7 32330017 J. Am. Chem. Soc. 2020 10.1021/jacs.0c03152 0 0 0 605 *mRNA|CCR3 protein, human|CC Chemokine Receptor 3|CCL11 protein, human|Chemokine CCL11|CCL24 protein, human|Chemokine CCL24|Protein Binding|tyrosine O-sulfate|Tyrosine|Amino Acid Sequence|Binding Sites|*Genetic Code|Protein Processing, Post-Translational 784 CCL7 32217106 Cancer Lett. 2020 10.1016/j.canlet.2020.03.018 1 0 0 605 *Podosomes|*Chemokine CCL7|*Matrix Metalloproteinase 9|Phosphatidylinositol 3-Kinases|Signal Transduction|RHOA protein, human|rhoA GTP-Binding Protein|Cell Line, Tumor|Extracellular Matrix|Lung Neoplasms|Upregulation|Receptor, CCR3|Collagen|Liver 784 CCL8 32651260 Cancer Res. 2020 10.1158/0008-5472.CAN-20-0034 0 0 0 371 Mice|Animals|*Monocytes|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|*Macrophage|Receptors, CCR2|Antigens, Ly|Mice, Inbred C57BL|Spleen|Phenotype|Inflammation|Disease Models, Animal|T-Lymphocytes 501 CCL8 32535027 iScience 2020 PMC7300153 10.1016/j.isci.2020.101217 0 0 0 371 Humans|Female|Animals|CCL8 protein, human|*Chemokine CCL8|*Postpartum|*Macrophages|Mammary Glands, Animal|Tumor Microenvironment 501 CCL8 32471866 J. Biol. Chem. 2020 10.1074/jbc.RA120.014103 0 0 0 371 Animals|*Chemokines|peptide B|Receptors, Chemokine|CCL18 protein, human|Chemokines, CC|Protein Binding|Amino Acid Sequence|Ligands|Chemotaxis|Ticks|Cell Movement|Inflammation 501 CCL8 32442811 Vet. Immunol. Immunopathol. 2020 10.1016/j.vetimm.2020.110058 0 0 0 371 Horses|Animals|*Lipopolysaccharides|*Synovitis|*Inflammation|Horse Diseases|Intraarticular Injections|Lameness, Animal|Synovial Fluid|Anti-Inflammatory Agents|*Gene Expression|Cytokines 501 CCL8 32432500 Biosci. Biotechnol. Biochem. 2020 10.1080/09168451.2020.1762160 0 0 0 371 Humans|*Becaplermin|*Smooth Muscle Cells|Muscle, Smooth, Vascular|*Aorta|Proto-Oncogene Proteins c-sis|Cell Proliferation|Cell Movement|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Phosphorylation|Cell Cycle|Phases, G1|*Chemokines|Signal Transduction|Cells, Cultured|*Ligands|Atherosclerosis|Upregulation 501 CCL8 32377537 J Immunol Res 2020 PMC7191376 10.1155/2020/8074183 0 0 0 371 *Latent Tuberculosis|Tuberculosis|Interferon-gamma Release Tests|Mycobacterium tuberculosis|Antigens, Bacterial|Cytokines|ROC Curve|Case-Control Studies|*Research Design|Biomarkers|Diagnosis, Differential 501 CCL8 32371294 Domest. Anim. Endocrinol. 2020 10.1016/j.domaniend.2020.106475 0 0 0 371 Pregnancy|Female|Animals|Swine|*Endothelial Cells|*Endometrium|CXCL12 protein, human|Chemokine CXCL12|CXCL8 protein, human|Interleukin-8|CXCR3 protein, human|Receptors, CXCR3|CXCL9 protein, human|Chemokine CXCL9|Cytokines|Cell Movement|Cells, Stromal|mRNA 501 CCL8 32330120 Aging (Albany NY) 2020 PMC7202544 10.18632/aging.103104 0 0 0 371 Humans|Mice|Animals|*Hyperplasia|*Smooth Muscle Cells|Vascular Smooth Muscle|Neointima Formation|Carotid Artery Injuries|Arterial Intima|Nik related kinase|*Protein-Serine-Threonine Kinases|Cell Proliferation|*Intracellular Signaling Peptides and Proteins|Cultured Cells|Cell Movement|Platelet-Derived Growth Factor|Inflammation|RNA Interference|siRNA 501 CCL8 32307587 Int J Colorectal Dis 2020 PMC7320065 10.1007/s00384-020-03582-2 0 0 0 371 Humans|*Anastomotic Leak|Early Detection of Cancer|Colorectal Surgery|*Digestive System Surgical Procedures|Anastomosis, Surgical|*Biomarkers|Rectum|Postoperative Complications|CXCL5 protein, human|*Chemokine CXCL5|Risk Factors|Colorectal Neoplasms|CCL8 protein, human|Chemokine CCL8 501 CCL8 32299786 J Microbiol Immunol Infect 2020 10.1016/j.jmii.2020.03.030 0 0 0 371 Child|Humans|*Mycoplasma pneumoniae|*Pneumonia, Mycoplasma|Cytokines|Community-Acquired Infections|L-Lactate Dehydrogenase 501 CCL8 32280674 Biomed Res Int 2020 PMC7115052 10.1155/2020/1497175 0 0 0 371 Humans|*Dermatitis, Atopic|TLR2 protein, human|*Toll-Like Receptor 2|*Leukocytes, Mononuclear|*Chemokines|*Eczema|Chemokine CCL17|Skin|Chemokine CCL22|*Leukocytes|*Mononuclear Phagocyte System|RNA, Messenger 501 CCL8 32213184 J Neuroinflammation 2020 PMC7098135 10.1186/s12974-020-01759-8 1 0 0 371 Humans|*Chemokines|*Leukocytes|Neutrophil Infiltration|Chemokine CXCL2|*Brain|Neutrophils|Inflammation|*Endotoxins 501 CCL8 32192892 Urol. Oncol. 2020 10.1016/j.urolonc.2020.02.021 0 0 0 371 *Urinary Bladder Neoplasms|Neoplasm Recurrence, Local|*Immunotherapy|Cytokines|*Immunologic Factors|Mycobacterium bovis|Chemokines|*Cancer Stem Cells 501 CCL8 32119150 Reprod. Domest. Anim. 2020 10.1111/rda.13663 0 0 0 371 Female|Pregnancy|Swine|Animals|Chemokines|Luteolysis|Chemokines CCL2|Receptor, CCR5|Corpus Luteum|Luteal Cells|Chemokine CCL4|Cytokines|Upregulation|Estrous Cycle|RNA, Messenger|Gene Expression 501 CCL8 32000634 Arch Suicide Res 2020 10.1080/13811118.2019.1649772 0 0 0 371 Male|Humans|Aged|*Suicidal Ideation|*Depressive Disorder, Major|CCL8 protein, human|Chemokine CCL8 501 CCL8 31940694 J. Vet. Sci. 2020 PMC7000894 10.4142/jvs.2020.21.e15 0 0 0 371 Mice|Horses|Animals|*Dinitrochlorobenzene|*BALB C Mice|Atopic Dermatitis|Skin|Anti-Inflammatory Agents|Immunoglobulin E|Cytokines|Plant Extracts 501 CCL8 31932428 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC6995029 10.1073/pnas.1901294117 0 0 0 371 Mice|Animals|connexin 47|*Multiple Sclerosis|*Oligodendroglia|*Connexins|Experimental Autoimmune Encephalomyelitis|GJA1 protein, human|Cx43|Gap Junctions|*Disease Models, Animal|Mice, Knockout|Myelin Sheath|Myelin-Oligodendrocyte Glycoprotein|Astroglias|Microglia|Spinal Cord|Inflammation 501 CCL8 31911451 Cancer Discov 2020 PMC7224338 10.1158/2159-8290.CD-19-0958 3 0 0 371 Humans|Mice|Animals|*T-Lymphocytes, Regulatory|*Tumor Microenvironment|*Lymphocyte Depletion|*Carcinogenesis|Pancreatic Cancer|Immune Tolerance|*Pancreas|Immunosuppression|Disease Models, Animal 501 ccm2 32640906 Arterioscler. Thromb. Vasc. Biol. 2020 10.1161/ATVBAHA.120.314586 0 0 0 198 Animals|*Hemangioma, Cavernous, Central Nervous System|Endothelial Cells|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Microtubule-Associated Proteins|Membrane Proteins|*Brain|Signal Transduction|Mutation|Cardiovascular System|Disease Models, Animal|*Apoptosis 261 ccm2 32540493 Genomics 2020 10.1016/j.ygeno.2020.06.010 0 0 0 198 Humans|*Lung|Idiopathic Pulmonary Fibrosis|Chronic Obstructive Pulmonary Disease|*Lung Diseases|*Biomarkers|Asthma|*Chronic Disease|UBQLN4 protein, human|Carrier Proteins|Nuclear Proteins|TOM1L1 protein, human|Adaptor Proteins, Signal Transducing|PAIP2 protein, human|Repressor Proteins|RNA-Binding Proteins 261 ccm2 32524570 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_31 0 0 0 198 Animals|Mice|Familial cerebral cavernous malformation|*Hemangioma, Cavernous, Central Nervous System|Endothelial Cells|KRIT1 protein, human|KRIT1 Protein|*Cell Signaling|Proto-Oncogene Proteins|Apoptosis Regulatory Proteins|Microtubule-Associated Proteins|Carrier Proteins|Membrane Proteins|Mutations|*Cytoplasm|Permeability, Vascular 261 ccm2 32524569 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_30 0 0 0 198 Humans|*Cerebral Cavernous Malformations|*Sequestosome-1 Protein|KRIT1 protein, human|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Mutations|Microtubule-Associated Proteins|Membrane Proteins|Carrier Proteins|*Immunofluorescence|Genetic Predisposition to Disease|Autophagy|Signal Transduction|SQSTM1 protein, human 261 ccm2 32524566 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_27 0 0 0 198 Animals|Humans|*Cavernous Malformation, Cerebral|KRIT1 protein, human|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Endothelial Cell|Phenotypes|Microtubule-Associated Proteins|Membrane Proteins|*Cell Proliferation|Carrier Proteins|Mutation 261 ccm2 32524563 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_24 0 0 0 198 Humans|Mice|Animals|Endothelial Cells|KRIT1 protein, human|KRIT1 Protein|Hemangioma, Cavernous, Central Nervous System|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|*Signal Transduction|Microtubule-Associated Proteins|Membrane Proteins|Carrier Proteins|Mutation|Phenotype|Zebrafish 261 ccm2 32524560 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_21 0 0 0 198 *Hemangioma, Cavernous, Central Nervous System|KRIT1 protein, human|KRIT1 Protein|radixin|Membrane Proteins|Microtubule-Associated Proteins|Proto-Oncogene Proteins|Carrier Proteins|Apoptosis Regulatory Proteins|Mutations|*Crystallography|moesin|Microfilament Proteins|Signal Transduction|Protein Binding|Repeat Domain, Ankyrin|Cerebral Cavernous Malformations 3|Micrognathism 261 ccm2 32524557 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_18 0 0 0 198 Humans|Mice|Animals|*Hemangioma, Cavernous, Central Nervous System|*Animals, Newborn|Cre recombinase|KRIT1 protein, human|KRIT1 Protein|Proto-Oncogene Proteins|Apoptosis Regulatory Proteins|*Disease Models, Animal|Mutations|Microtubule-Associated Proteins|Cerebral Cavernous Malformations 2|Micrognathism|Membrane Proteins|Intellectual Disability|Ribs 261 ccm2 32524556 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_17 0 0 0 198 Humans|Mice|Animals|*Zebrafish|KRIT1 Protein|Hemangioma, Cavernous, Central Nervous System|*Disease Models, Animal|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Membrane Proteins|Microtubule-Associated Proteins|Signal Transduction|Mutation|Morphogenesis|Neovascularization, Pathologic 261 ccm2 32524552 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_13 0 0 0 198 Humans|*CRISPR-Cas Systems|*Endothelial Cell|*CRISPR|Genome Editing|Cas9 Protein|Hemangioma, Cavernous, Central Nervous System|Transfection|Ribonucleoproteins 261 ccm2 32524551 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_12 0 0 0 198 Animals|Mice|*Cavernous Malformation, Cerebral|KRIT1 protein, human|*KRIT1 Protein|Microtubule-Associated Proteins|Oxidative Stress|Proto-Oncogene Proteins|Autophagy|Knockout Mouse|Redox|Homeostasis|Inflammation|Fibroblasts 261 ccm2 32524544 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_5 0 0 0 198 Humans|*Hemangioma, Cavernous, Central Nervous System|*High-Throughput Nucleotide Sequencing|KRIT1 Protein|*Genetic Testing|Pedigree|Proto-Oncogene Proteins|Whole Exome Sequencing|Phenotype|Microtubule-Associated Proteins|Mutation|Carrier Proteins|Genome 261 ccm2 32524543 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_4 0 0 0 198 *Hemangioma, Cavernous, Central Nervous System|Endothelial Cells|KRIT1 Protein|*Genetic Screening|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Mutation|Microtubule-Associated Proteins|Membrane Proteins|Carrier Proteins|Allele|RNA Splicing|Mutations, Germline 261 ccm2 32524540 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_1 0 0 0 198 Humans|Animals|*Hemangioma, Cavernous, Central Nervous System|KRIT1 protein, human|KRIT1 Protein|Proto-Oncogene Proteins|Microtubule-Associated Proteins|Endothelial Cell|Mutation|Autophagy|Oxidative Stress|*Molecular Targeted Therapies|Redox 261 ccm2 32515053 FASEB J. 2020 10.1096/fj.201902888R 0 0 0 198 Humans|*Endothelial Cells|FN1 protein, human|*Fibronectins|KRIT1 protein, human|*KRIT1 Protein|Cerebral Cavernous Malformations|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|*Phenotype|Membrane Proteins|Carrier Proteins|Microtubule-Associated Proteins|Mutation|CCM2 protein, human 261 ccm2 32502201 PLoS Biol. 2020 PMC7299406 10.1371/journal.pbio.3000734 0 0 0 198 Mice|Animals|*Hemangioma, Cavernous, Central Nervous System|cadherin 5|KRIT1 protein, human|KRIT1 Protein|*Cadherins|*Antigens, CD|Proto-Oncogene Proteins|Apoptosis Regulatory Proteins|Endothelial Cell|Mutation|Carrier Proteins|Microtubule-Associated Proteins|Membrane Proteins|Disease Models, Animal|MicroRNAs 261 ccm2 32348981 Cerebrovasc. 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Rep. 2020 PMC7160551 10.3892/or.2020.7550 0 0 0 198 Humans|Animals|*Hemangioma, Cavernous, Central Nervous System|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Membrane Proteins|Carrier Proteins|Microtubule-Associated Proteins|*Cell Transformation, Neoplastic|*Tumorigenesis|Mutation|*Cancers|Signal Transduction|Neovascularization, Pathologic|Morphogenesis|*Biomarkers|KRIT1 protein, human 261 CCNQ 32433072 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000316 0 0 0 37 Humans|Delirium|Intensive Care Units|Critical Care Nursing|Risk Factor 1015 CCNQ 32433071 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000315 0 0 0 37 Humans|*Artificial Intelligence|Caring|Workload|Robotics|Technology, Health Care|Healthcare 1015 CCNQ 32433070 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000314 0 0 0 37 Humans|*Touch|*Humanities|*Touch Perception|*Patient Care|*Technology|*Therapeutic Touch|Caring|Biomedical Technology 1015 CCNQ 32433069 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000313 0 0 0 37 Humans|*Shivering|*Targeted Temperature Management|Out-of-Hospital Cardiac Arrest|Cardiopulmonary Resuscitation|*Energy Expenditure|Prospective Studies 1015 CCNQ 32433068 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000312 0 0 0 37 Humans|*Respiration, Artificial|Cross-Sectional Studies|Critical Care Nursing|Intensive Care Units|Nursing Staff, Hospital|Attitude of Health Personnel|Questionnaire|*Knowledge|Health Knowledge, Attitudes, Practice 1015 CCNQ 32433067 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000311 0 0 0 37 Humans|*Critical Care|Lactate|Point-of-Care Testing|Sepsis|Cardiac Surgical Procedures|*Diagnostic Tests, Routine 1015 CCNQ 32084066 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000305 0 0 0 37 Humans|*Shivering|*Targeted Temperature Management|Arrest, Cardiac|Hypothermia|Brain Injury 1015 CCNQ 32084065 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000304 1 0 0 37 Humans|*Critical Illness|*Melatonin|suvorexant|ramelteon|*Dexmedetomidine|*Azepines|*Indenes|*Sleep|*Triazoles|Intensive Care Unit|Delirium|Sleep Wake Disorders|Critical Care 1015 CCNQ 32084064 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000303 0 0 0 37 Humans|United States|*Cannabinoids|Multiple Sclerosis|Epilepsy|*Neurosciences 1015 CCNQ 32084063 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000306 0 0 0 37 Humans|*Parkinson Disease|Hospitalizations|Medication Errors|Length of Stay|Pharmacists|Hospital|Pharmaceutical Preparations|Providers, Healthcare|Intensive Care Units 1015 CCNQ 32084062 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000302 0 0 0 37 Humans|tisagenlecleucel|*T Cell Receptor|axicabtagene ciloleucel|Immunotherapy, Adoptive|Receptors, Chimeric Antigen|Antigens, CD19|Lymphoma, B-Cell|Immunotherapies|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Cytokines|Neurotoxicity Syndrome|Burkitt Lymphoma|T-Lymphocytes 1015 CCNQ 32084061 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000301 0 0 0 37 Humans|*Traumatic Brain Injury|Cognition Disorders|Selective Serotonin Reuptake Inhibitors|Methylphenidate|Brain Injuries|Central Stimulants|Tricyclic Antidepressants|Anxiety Disorders|Anxiety|*Disease Progression|Amantadine|Modafinil|Sleep Wake Disorders|Serotonin 1015 CCNQ 32084060 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000300 0 0 0 37 Humans|*Critical Illness|Retrospective Studies|Prospective Studies|Intensive Care Units|Vancomycin|Aminoglycosides|Anti-Bacterial Agents|Alteplase|Nicardipine 1015 CCNQ 32084059 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000299 0 0 0 37 Humans|United States|*Vasospasm, Intracranial|*Subarachnoid Hemorrhage|Nimodipine|Cerebral Infarction|Brain Ischemia|Vasodilator Agents|Strokes|Treatment Outcome 1015 CCNQ 32084058 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000298 0 0 0 37 Humans|*Acute Stroke|*Platelet Aggregation Inhibitors|*Brain Ischemia|Transient Ischemic Attack|Clopidogrel|Aspirin|Ticlopidine|Secondary Prevention|Bleeding|Drug Therapy, Combination|*Dual Anti-Platelet Therapy|*Ischemia 1015 CCNQ 32084057 Crit Care Nurs Q 2020 10.1097/CNQ.0000000000000297 0 0 0 37 Humans|Adult|*Acute Stroke|*Brain Ischemia|*Blood Pressure|Alteplase|Thrombectomy|Fibrinolytic Agents|Cerebral Blood Flow|Hemorrhage|*Blood Pressure Determination|*Ischemia 1015 CCNY 32659312 Neurosci. Lett. 2020 10.1016/j.neulet.2020.135241 0 0 0 232 Humans|*Cues|*Smokers|*Attentional Bias|*Pilot Projects|*Smoking|*Potential, Event-Related|Smoking Cessation|*Tobacco Smoking|*Whites|Attention|Craving|Reaction Time|Orientations|Cognition 700 CCNY 32606977 Cancer Manag Res 2020 PMC7320751 10.2147/CMAR.S241620 0 0 0 232 Humans|*Laryngeal Neoplasms|*Signal Transduction|*MEK-ERK Pathway|Cell Proliferation|Cyclins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|RNA, Small Interfering 700 CCNY 32601712 J. Membr. Biol. 2020 10.1007/s00232-020-00128-z 0 0 0 232 *Lipid Bilayers|Antimicrobial Cationic Peptides|Molecular Dynamics Simulation|Cell Membrane|*Oxidation-Reduction|*Anti-Bacterial Agents 700 CCNY 32564792 Adv Child Dev Behav 2020 10.1016/bs.acdb.2020.05.005 0 0 0 232 Humans|Female|*Language|Stereotyping|Prejudice|Cognition 700 CCNY 32561554 J. Biol. Chem. 2020 PMC7307211 10.1074/jbc.H120.014383 0 0 0 232 Plasmodium falciparum|Protozoan Proteins|Cyclic GMP-Dependent Protein Kinases|Protein Binding|Amino Acid Sequence 700 CCNY 32531221 Biochim Biophys Acta Bioenerg 2020 10.1016/j.bbabio.2020.148239 0 0 0 232 *Protons|Cytochrome c Oxidase|Chain, Respiratory|Thermus thermophilus|Rhodobacter sphaeroides|Protein Conformation|Oxidation-Reduction|Static Electricity|Heme|Thermodynamics|Models, Molecular 700 CCNY 32531220 Biochim Biophys Acta Bioenerg 2020 10.1016/j.bbabio.2020.148240 0 0 0 232 *Protons|*Hydrogen Bonding|*Electron Transport Complex I|Molecular Dynamics|Chain, Respiratory|Oxidation-Reduction|Electron Transport Complex IV|Water|Electrons|Antiporters|Quinones|quinone|Benzoquinones 700 CCNY 32531016 Chem. Senses 2020 10.1093/chemse/bjaa039 0 0 0 232 Mice|Animals|*Olfactory Epithelium|Vomeronasal Organ|Olfactory Receptor Neurons|Epithelium|*Cell Proliferation|Epithelial Cells|*Cyclophosphamide 700 CCNY 32500172 J. Membr. Biol. 2020 PMC7360341 10.1007/s00232-020-00124-3 0 0 0 232 *Lipid Bilayers|protegrin-1|Antimicrobial Cationic Peptides|Molecular Dynamics Simulation|Cell Membrane|Hydrophobic and Hydrophilic Interactions 700 CCNY 32492509 Neuroimage 2020 10.1016/j.neuroimage.2020.117001 1 0 0 232 Humans|Adolescent|Child|*Magnetic Resonance Imaging|Reproducibility of Results|*Electroencephalography|Brain|Nerve Net|Neural Pathways|Attention Deficit-Hyperactivity Disorder|*Phenotype 700 CCNY 32401167 Autophagy 2020 10.1080/15548627.2020.1756665 0 0 0 232 *AMP-Activated Protein Kinases|*Autophagy|Cyclin-Dependent Kinases|Cyclins|Phosphorylation|Protein Binding 700 CCNY 32398662 Sci Rep 2020 PMC7217846 10.1038/s41598-020-64385-7 0 0 0 232 *Electrons|*Magnetic Field 700 CCNY 32355274 Nat Commun 2020 PMC7193630 10.1038/s41467-020-15705-y 1 0 0 232 *Anatomy, Regional|Acoustic|Commuting 700 CCNY 32339105 J Affect Disord 2020 10.1016/j.jad.2020.03.056 1 0 0 232 Humans|*Mental Health|*Depression|*Promotion of Health|Clergy|Health Surveys|Patient Health Questionnaire|Methodist|Prevalence|Longitudinal Survey|North Carolina 700 CCNY 32289703 Brain Stimul 2020 PMC7196013 10.1016/j.brs.2020.02.019 0 0 0 232 Transcranial Direct Current Stimulation|*Cranial Nerves|*Cognition|Stimulation, Transcranial Magnetic|*Electrical Stimulation|Brain|Electroencephalography|Neuroimaging|Cerebral Cortex|Skull|Thalamus|Axons 700 CCNY 32289449 Mol. 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Chem. 2020 PMC7237834 10.1016/j.bmc.2020.115428 0 0 0 232 *Solanum tuberosum|Plant Tubers|Solanine|Erwinia carotovora|*Antibiotic|*Chemical Fractionation|Mass Spectrometry|Chromatography, High Pressure Liquid|Antioxidants|Chromatography, Liquid|Wound Healing|Tissue Extracts 700 CD133 32662250 FEBS Open Bio 2020 10.1002/2211-5463.12932 0 0 0 583 Carcinoma, Hepatocellular|Liver Cancer|*Cancer Stem Cells|EPCAM protein, human|EpCAM|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|*Liver 6012 CD133 32650569 Molecules 2020 10.3390/molecules25143128 0 0 0 583 ginsenoside Rg3|Ginsenosides|Ginseng|*Tumorigenesis|*Cancer Stem Cell|*Fermentations|CDH1 protein, human|N-Cadherin|Cell Line, Tumor|*Embryonal Carcinoma|*Fermentors|Cell Proliferation|Antigens, CD|Plant Extracts 6012 CD133 32649728 PLoS ONE 2020 10.1371/journal.pone.0234614 0 0 0 583 Humans|Rats|Animals|*Astrocytes|*Exosomes|*Neural Stem Cells|*Glioma|*Cell Differentiation|Glial Fibrillary Acidic Protein|growth inhibitory factor|Nerve Tissue Proteins|STAT3 protein, human|STAT3 Transcription Factor|Neurons|Co-culture|Cell Proliferation|Cells, Cultured|Interleukin 6 6012 CD133 32649042 Environ. 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Chem. 2020 10.1074/jbc.RA120.012590 0 0 0 583 Humans|*Interleukin-6|Vascular Endothelial Growth Factor A|KDR protein, human|*Vascular Endothelial Growth Factor Receptor-2|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|IL6R protein, human|Receptors, Interleukin-6|*Neovascularization, Pathologic|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|Signal Transduction|DNA Methylation|Neovascularization, Physiologic|Human Umbilical Vein Endothelial Cells|Promoter Regions, Genetic|Epigenesis, Genetic|Cell Proliferation 6012 CD133 32634135 PLoS ONE 2020 10.1371/journal.pone.0234986 0 0 0 583 Humans|*Glioblastoma|Neoplasm Recurrence, Local|Brain Neoplasms|Neoplastic Stem Cells|AC133 Antigen|NES protein, human|Nestin|Cell Line, Tumor|Antigens, CD|Neovascularization, Pathologic|Gene Expression Profiling|Cell Separation|Upregulation 6012 CD133 32633291 Chem Soc Rev 2020 10.1039/d0cs00379d 0 0 0 583 *Cancer Stem Cell|CD44 protein, human|Hyaluronan Receptors|Retinal Dehydrogenase|AC133 Antigen|Epithelial Cell Adhesion Molecule|Aldehyde Dehydrogenase|Antigens, CD|Cell Line, Tumor|Biomarkers, Tumor 6012 CD133 32632776 Transl Stroke Res 2020 10.1007/s12975-020-00834-9 0 0 0 583 Humans|*Endothelial Progenitor Cells|Prospective Studies|*Cerebral Revascularization|Moyamoya disease 1|Moyamoya Disease|*Neovascularization, Pathologic|Collateral Circulation|Treatment Outcome|*Progenitor B-Cells 6012 CD133 32632605 Mol. Neurobiol. 2020 10.1007/s12035-020-02004-2 0 0 0 583 Humans|Mice|Animals|*Glioblastoma|Temozolomide|CD44 protein, human|*Hyaluronan Receptors|Brain Neoplasms|Neoplastic Stem Cells|AC133 Antigen|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Immunohistochemistry|Biomarkers, Tumor 6012 CD133 32629871 Int J Mol Sci 2020 10.3390/ijms21134646 0 0 0 583 Humans|*Hemeoxygenase 1|*5 Fluorouracil|*NF-E2-Related Factor 2|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|*Pancreas|ATP-Binding Cassette Transporters|Antioxidants|RNA, Small Interfering|Upregulation|ABCG2 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 2|Neoplasm Proteins 6012 CD133 32629392 EBioMedicine 2020 PMC7339012 10.1016/j.ebiom.2020.102862 0 0 0 583 *Coronary Artery Disease|*Bone Marrow|*Myocardium|*Myocardial Infarction|*Coronary Artery Bypass|*Disease, Myocardial|*Hematopoietic Stem Cell|Bone Marrow Transplantation|*Myocardial Revascularization|Ventricular Function, Left|*Wound Healing|Regeneration|Stem Cell Transplantation|Bone Marrow Cells|Antigens, CD|*Phenotype|AC133 Antigen|Hematopoietic Stem Cell Transplantation 6012 CD133 32628717 PLoS ONE 2020 10.1371/journal.pone.0235852 0 0 0 583 *Medulloblastoma|*Astrocytes|Cerebellar Neoplasms|Cancer Stem Cell|AC133 Antigen|Antigens, CD|Glycoproteins|Cell Line, Tumor|Neural Stem Cell|Spheroids, Cellular|Cell Proliferation|*Phenotypes|Peptides|Upregulation|Media, Conditioned|Tumor Microenvironment 6012 CD133 32627042 Oncol. Rep. 2020 10.3892/or.2020.7612 0 0 0 583 Animals|Humans|Epigenesis, Genetic|*Cancer Stem Cell|*Chondrosarcoma|Aldehyde Dehydrogenase|Cell Line, Tumor|Bone Neoplasms|Antigens, CD|Biomarkers, Tumor|Cell Separation|Oncogenesis 6012 CD133 32627023 Oncol. Rep. 2020 10.3892/or.2020.7642 0 0 0 583 *Glioblastoma|salinomycin|Neoplasm Recurrence, Local|*Cancer Stem Cells|*Pyrans|Brain Neoplasms|Cell Line, Tumor|*Antineoplastic Agents|Xenograft Model Antitumor Assays|Apoptosis|Tumorigenesis 6012 CD133 32627006 Oncol. Rep. 2020 PMC7336517 10.3892/or.2020.7631 0 0 0 583 Neoplasm Recurrence, Local|*Wnt Signaling Pathways|beta Catenin|Cell Proliferation|*Catenins|Cancer Stem Cells|Upregulation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Tumor Necrosis Factor-alpha|*Cell Transformation, Neoplastic 6012 CD133 32621880 Nanomedicine 2020 10.1016/j.nano.2020.102261 0 0 0 583 Humans|Rats|Mice|Animals|*Lipids|*Administration, Oral|*Small Cell Lung Carcinoma|Curcumin|Bioavailability|Drug Carriers|Nanoparticles|Solubility|Antineoplastic Agents|Particle Size|*Polyphenols|*Polysaccharides|Lung Neoplasms 6012 CD133 32616888 Oncogene 2020 10.1038/s41388-020-1373-6 0 0 0 583 *Phosphatidylinositol 3-Kinases|Neoplasm Recurrence, Local|*Melanoma|Signal Transduction|Proto-Oncogene Proteins c-akt|Phosphoinositide-3 Kinase Inhibitors|Cell Line, Tumor|Drug Resistance, Neoplasm|Cell Proliferation|AC133 Antigen|*B Cells|Apoptosis|Antigens, CD|Stem Cells 6012 CD133 32614460 Liver Int. 2020 10.1111/liv.14585 0 0 0 583 *alpha-Fetoproteins|Carcinoma, Hepatocellular|Liver Neoplasms|*Extracellular Vesicle|Biliary Tract Neoplasms|Biomarkers, Tumor|Liquid Biopsy|Cancer Screening 6012 CD133 32606945 Cancer Manag Res 2020 PMC7305346 10.2147/CMAR.S252292 0 0 0 583 *Carcinoma, Squamous Cell|*Mouth Neoplasms|Neoplasm Recurrence, Local|*Cancer Stem Cells|AC133 Antigen|*Cell Division|*Mitochondria|SOXB1 Transcription Factors|Cell Line, Tumor|Xenograft Model Antitumor Assays 6012 CD133 32602015 Mol. 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Biochem. 2020 10.1007/s11010-020-03807-6 0 0 0 583 Humans|Female|Neoplasm Recurrence, Local|*Cancer Stem Cells|Signal Transduction|IGF1 protein, human|Insulin-Like Growth Factor I|Proto-Oncogene Proteins c-akt|Cell Line, Tumor|Phosphatidylinositol 3-Kinases|Cisplatin|Epithelial-Mesenchymal Transition|Cell Proliferation|*Carcinomas|Cervical Cancer|Apoptosis|B-insulin|*Insulin|*Biotin 6012 cd248 32591411 Cancer Res. 2020 10.1158/0008-5472.CAN-19-2691 0 0 0 366 Humans|Mice|Animals|*Carcinoma, Hepatocellular|Mice, Nude|*Liver Neoplasms|CD248 protein, human|*Antigens, Neoplasm|*Antigens, CD|*Fibroblasts|Pericytes|*Macrophages|Neoplasm Proteins|Cell Line, Tumor|*Cell Count|CD68 protein, mouse|Antigens, Differentiation, Myelomonocytic 114 cd248 32107922 Cancer Control 2020 PMC7053787 10.1177/1073274820903351 0 0 0 366 Humans|*Prognosis|*Colorectal Cancer|CA-19-9 Antigen|Carcinoembryonic Antigen|CD248 protein, human|Biomarkers, Tumor|*Antigens, CD|Cancer Early Diagnosis|*Colonic Neoplasms|*Disease Progression|Enzyme-Linked Immunosorbent Assay 114 cd248 31993928 Mol Imaging Biol 2020 PMC7343747 10.1007/s11307-020-01479-8 0 0 0 366 Animals|Humans|Mice|CD248 protein, human|Antigens, Neoplasm|tumor endothelial marker 1, mouse|Antigens, CD|*Radiometry|Neoplasm Proteins|Immunoglobulin Fragments|Antibodies, Monoclonal|Positron-Emission Tomography|Cell Line, Tumor|Sarcoma|Tumor Microenvironment 114 cd248 31964365 BMC Pulm Med 2020 PMC6975017 10.1186/s12890-020-1054-9 1 0 0 366 Humans|*Fibroblast|Idiopathic Pulmonary Fibrosis|*Cell Differentiation|Lung|Cells, Cultured|*Biomarkers|Signal Transduction|*Organogenesis|Integrins|CD248 protein, human|Antigens, Neoplasm|Antigens, CD 114 cd276 32642118 J Thorac Dis 2020 PMC7330387 10.21037/jtd.2020.04.41 0 0 0 847 Humans|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Signal Transduction|A549 Cells|Cell Movement|*Disease Progression|RNA, Long Noncoding|Prognosis|MicroRNAs|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Line, Tumor|Cell Proliferation|Kaplan-Meier Estimate|*Transcription Factors|Integrins|CD276 protein, human|B7 Antigens 364 cd276 32548602 Chin J Dent Res 2020 10.3290/j.cjdr.a44747 0 0 0 847 *Carcinoma, Squamous Cell|*Mouth Neoplasms|B7 Antigens|Cell Line, Tumor 364 cd276 32544882 Aging (Albany NY) 2020 PMC7343492 10.18632/aging.103395 0 0 0 847 Humans|*Carcinoma, Hepatocellular|*Liver Cancer|B7 Antigens|B7-H1 Antigen|Cancer Microenvironment|CD8-Positive T-Lymphocytes|Immunotherapy|*Immunologic Factors|CD276 protein, human 364 cd276 32398947 Int. J. Biol. Sci. 2020 PMC7211166 10.7150/ijbs.41105 0 0 0 847 Humans|Male|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Immunotherapy|B7 Antigens|Lymphocyte Activation|Prostate Cancer|Signal Transduction|CD276 protein, human 364 cd276 32377564 NPJ Breast Cancer 2020 PMC7190737 10.1038/s41523-020-0158-y 0 0 0 847 Humans|*Carcinoma, Intraductal, Noninfiltrating|Photoacoustic Techniques|B7 Antigens|Molecular Imaging|CD276 protein, human 364 cd276 32341579 Nat. Med. 2020 10.1038/s41591-020-0821-8 0 0 0 847 Humans|Child|Child, Preschool|*Rhabdoid Tumor|SMARCB1 Protein|*Central Nervous System Neoplasms|*Transcription Factors|Teratoma|Brain Neoplasms|Cell Line, Tumor|Xenograft Model Antitumor Assays|Combined Modality Therapy|T-Lymphocytes 364 cd276 32283920 ACS Comb Sci 2020 PMC7263704 10.1021/acscombsci.0c00036 0 0 0 847 Animals|*Saccharomyces cerevisiae|*Ligands|*Yeast, Dried|Peptide Library|Protein Engineering|Protein Binding|FN1 protein, human|Fibronectin|*B Cells|*Immunomagnetic Separation|*Mammals|EGFR protein, human|Epidermal Growth Factor Receptor|Magnetic Phenomena 364 cd276 32166218 Antib Ther 2020 PMC7052794 10.1093/abt/tbaa002 0 0 0 847 Humans|Rabbits|Mice|Animals|*Single-Domain Antibodies|*Immunizations|*Cell Surface Display Techniques|Immunoglobulin Variable Region|Peptide Library|Antibody Affinity|*Vaccination|Epitopes|Amino Acid Sequence|Cloning, Molecular|Antibodies, Monoclonal|Enzyme-Linked Immunosorbent Assay|Bacteriophages|CD276 protein, human|B7 Antigens 364 cd276 32145124 Brain Pathol. 2020 10.1111/bpa.12829 1 0 0 847 *Medulloblastoma|CDK6 protein, human|*Cyclin-Dependent Kinase 6|Cerebellar Neoplasms|RNA, Micro|Cell Proliferation|Downregulation|Gene Expression Regulation, Neoplastic|*Genes, cdc|Cell Line, Tumor|Apoptosis|*Genes, Regulator|Cell Cycle Arrest|Tumorigenesis|*Transcription Factors|Epigenesis, Genetic 364 cd276 31998416 Dis. Markers 2020 PMC6977319 10.1155/2020/5354825 0 0 0 847 *Adrenocortical Carcinoma|*Prognosis|Adrenal Cortex Neoplasms|Adrenalectomy|Neoplasm Recurrence, Local|*Transcription Factors 364 cd276 31960110 Cancer Immunol. Immunother. 2020 PMC7113210 10.1007/s00262-019-02475-w 0 0 0 847 Humans|*Neoadjuvant Therapy|*Monitoring, Immunologic|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Esophagectomy|Chemoradiotherapy|Gene Expression Regulation, Neoplastic|CTLA4 protein, human|CTLA-4 Antigen|Esophagus|Up-Regulation|Immunotherapy|Cell Proliferation|Transcription Factors|Tumor Microenvironment|CD276 protein, human|B7 Antigens 364 cd276 31950059 Biomed Res Int 2020 PMC6948356 10.1155/2019/9301989 0 0 0 847 Humans|*Osteosarcoma|miRNAs|Bone Neoplasms|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|RNA, Messenger|Gene Ontology|Cell Line, Tumor|Downregulation|circRNAs|Disease Progression|*Transcription Factors 364 cd276 31948091 Cells 2020 PMC7016770 10.3390/cells9010124 1 0 0 847 *Endothelial Cells|*Colorectal Cancer|Neoplastic Cells, Circulating|Bevacizumab|Cell Count|Antineoplastic Combined Chemotherapy Protocols|Biomarkers, Tumor|Antibodies, Monoclonal, Humanized|CD146 Antigen|Kaplan-Meier Estimate|*B Cells|Flow Cytometry|*Colonic Neoplasms 364 cd276 31903901 Med Sci (Paris) 2020 10.1051/medsci/2019193 0 0 0 847 PDCD1 protein, human|Programmed Cell Death 1 Receptor|CTLA4 protein, human|CTLA-4 Antigen|Antineoplastic Agents, Immunological|Immunotherapy|CD274 protein, human|B7-H1 Antigen|Antibodies, Monoclonal|TNFRSF9 protein, human|Tumor Necrosis Factor Receptor Superfamily, Member 9|Neoplasms|NK Cells|Medical Oncology|T-Lymphocytes|Killer Cell Immunoglobulin-Like Receptor|Lymphocyte Activation|Immunologic Factors 364 CD5L 32611589 J. Am. Soc. Nephrol. 2020 10.1681/ASN.2019100987 0 0 0 193 Mice|Animals|*Glomerulonephritis, IGA|*Kidney Glomerulus|Immunoglobulin A|*Inflammation|Immunoglobulin G|Hematuria|*Macrophage|Mice, Inbred Strains|*Urinary Tract|Disease Models, Animal|Cd5l protein, mouse|Receptors, Immunologic|Apoptosis Regulatory Proteins 98 CD5L 32558599 Amyotroph Lateral Scler Frontotemporal Degener 2020 10.1080/21678421.2020.1779303 0 0 0 193 Humans|Amyotrophic Lateral Sclerosis 2, Juvenile|CLU protein, human|*Clusterin|*Gelsolin|ficolin|Amyotrophic Lateral Sclerosis|Biomarkers|Mass Spectrometry|Cohort Studies|Disease Progression|Proteomics|Cognitive Impairment|Enzyme-Linked Immunosorbent Assay 98 CD5L 32256738 Exp Ther Med 2020 PMC7086238 10.3892/etm.2020.8497 0 0 0 193 Animals|*Autophagy|ATG7 Protein|*Cell Differentiation|Ischemia-Reperfusion Injury|Apoptosis|Hepatocytes|Liver|Signal Transduction|RNA, Small Interfering|Oxidative Stress|Disease Models, Animal 98 CD5L 32194022 Clin. Exp. Rheumatol. 2020 0 0 0 193 Humans|*Rheumatoid Arthritis|Blood Sedimentation|Synovial Fluid|Osteoarthritis|C-Reactive Protein|Tumor Necrosis Factor-alpha|*Apoptosis Regulatory Proteins|*Macrophage|Enzyme-Linked Immunosorbent Assay|Apoptosis 98 CD5L 32183611 Thyroid 2020 10.1089/thy.2019.0635 1 0 0 193 98 CD5L 32148377 World J. Gastroenterol. 2020 PMC7052538 10.3748/wjg.v26.i8.789 0 0 0 193 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Tumor Microenvironment|*Prognosis|Biomarkers, Tumor|RNA, Long Noncoding|Gene Expression Profiling|Kaplan-Meier Estimate|Gene Expression Regulation, Neoplastic|Databases, Genetic|Transcriptome|ROC Curve 98 CD5L 31931372 Int. Immunopharmacol. 2020 PMC7031035 10.1016/j.intimp.2020.106187 1 0 0 193 Animals|*Th17 Cells|Encephalomyelitis, Autoimmune, Experimental|Interleukin-17|Cell Differentiation|Autoimmunity|Signal Transduction|Phenotype 98 CD71 32588489 J. Clin. Lab. Anal. 2020 10.1002/jcla.23420 0 0 0 4117 Pregnancy|Female|Humans|*Erythroblasts|*Cell Separation|CD71 antigen|*Receptors, Transferrin|*Fetus|*Antigens, CD|*Prenatal Care|Maternal-Fetal Exchange|Immunomagnetic Separation|Prenatal Diagnosis|Fetal Blood|Antigens, Differentiation, B-Lymphocyte|*Erythrocyte Count|In Situ Hybridization, Fluorescence|*Magnetic|*Blood Cell Count|Magnetic Phenomena 2164 CD71 32582860 Sci Adv 2020 PMC7292630 10.1126/sciadv.abb3900 0 0 0 4117 Mice|Animals|*Cyclosporine A|*Disease Models, Animal|*Lupus Erythematosus, Systemic|*Glomerulonephritis|*Lupus Erythematosus, Discoid|Mice, Inbred MRL lpr|*Nanoparticle|Antibodies, Antinuclear|Immunosuppressive Agents|*Lymphatic System|CD71 antigen|Receptors, Transferrin|gambogic acid|Xanthones|Antigens, CD 2164 CD71 32572998 Environ. Mol. Mutagen. 2020 10.1002/em.22393 0 0 0 4117 Male|Female|Humans|*Reticulocytes|*Flow Cytometries|*Mutation|Micronucleus Tests|Mutagens|CD71 antigen|Receptors, Transferrin|Erythrocytes|Antigens, CD|Membrane Proteins 2164 CD71 32556188 J. Infect. Dis. 2020 10.1093/infdis/jiaa177 0 0 0 4117 Animals|Humans|*Malaria, Vivax|*Bone Marrow|Plasmodium vivax|Malaria|Erythropoiesis|*Bone and Bones 2164 CD71 32552958 Zhongguo Shi Yan Xue Ye Xue Za Zhi 2020 10.19746/j.cnki.issn.1009-2137.2020.03.033 0 0 0 4117 Child|Humans|Female|Pregnancy|alpha-Thalassemia|beta-Thalassemia|*Mutation|Genotype|China|*Biochemical Phenomena 2164 CD71 32543774 Cytometry B Clin Cytom 2020 10.1002/cyto.b.21931 0 0 0 4117 *Flow Cytometries|*Bone Marrow|*Radar|*Myelodysplastic Syndromes|Immunophenotyping|Erythropoiesis|Antigens, CD|Bone Marrow Cells|Cell Count|Case-Control Studies 2164 CD71 32518401 Nat. Biotechnol. 2020 PMC7294996 10.1038/s41587-020-0456-9 1 0 0 4117 Humans|*RNA, Guide|CRISPR|CRISPR-Cas Systems|CRISPR-Associated Proteins|Genome|RNA 2164 CD71 32483133 Sci Rep 2020 PMC7264208 10.1038/s41598-020-65851-y 0 0 0 4117 *Monocytes|*Diabetes Mellitus, Type 1|*Plasmacytoid Dendritic Cells|*DNA|Lymphocyte Activation|CD71 antigen|Antigens, CD|Interferon-alpha|Cells, Cultured|Receptors, Transferrin 2164 CD71 32456797 Biochem. Biophys. Res. Commun. 2020 10.1016/j.bbrc.2020.04.143 0 0 0 4117 Humans|Mice|Animals|GATA1 protein, human|*GATA1 Transcription Factor|Progenitors, Megakaryocyte-Erythroid|Megakaryocytes|Thrombopoietin|Erythropoiesis|Cell Differentiation|Antigens, CD34|Doxycycline|Cells, Cultured|Gene Expression Regulation 2164 CD71 32450207 Exp. Hematol. 2020 10.1016/j.exphem.2020.05.005 0 0 0 4117 Erythropoiesis|CD71 antigen|*Receptors, Transferrin|EPO protein, human|Erythropoietin|Erythroid Precursor Cells|*Antigens, CD|Spleen|Red Blood Cells|Cell Proliferation|Erythrocyte Count|PTPRC protein, human|Leukocyte Common Antigens 2164 CD71 32429209 Cells 2020 PMC7290576 10.3390/cells9051227 0 0 0 4117 Rats|Animals|*Endothelial Cells|*Liver Cirrhosis|*Antigen-Presenting Cells|*Th17 Cells|Liver|*Endothelium|Lymphocyte Activation|*B Cells|Kupffer Cells|Carbon Tetrachloride|Cell Differentiation|*Mononuclear Phagocyte System|*Hepatic Veins 2164 CD71 32407296 JCI Insight 2020 PMC7308060 10.1172/jci.insight.135751 0 0 0 4117 Humans|Infant|Child|Mice|Animals|Child, Preschool|Biliary Atresia|Rotavirus|*Liver|Rotavirus Infections|Cholestasis|Bile Ducts, Extrahepatic|Mice, Inbred BALB C|*Hepatic Cells|Killer Cells, Natural|Animals, Newborn|Disease Models, Animal|CD71 antigen|*Antigens, CD|*Receptors, Transferrin|*Cells, Erythroid 2164 CD71 32358067 J. Biol. Chem. 2020 PMC7278357 10.1074/jbc.RA119.011679 0 0 0 4117 cholesterol-binding protein|*Erythroblasts|Carrier Proteins|Erythropoiesis|TYRP1 protein, human|*Membrane Glycoproteins|*Biological Transport|Cell Differentiation|Cholesterol|Cell Proliferation 2164 CD71 32355561 Clin Transl Immunology 2020 PMC7190396 10.1002/cti2.1133 0 0 0 4117 B Cells|B-Lymphocyte Subsets|Plasma Cells|Immunophenotyping|Immunologic Memory|Flow Cytometry|Multiple Sclerosis 2164 CD71 32284314 Immunohorizons 2020 10.4049/immunohorizons.2000003 0 0 0 4117 Humans|*Iron|*Helper Cells|Lymphocyte Activation|CD28 Antigens|CD71 antigen|Antigens, CD|Antigens, Differentiation, T-Lymphocyte|Antigen-Presenting Cells|Interleukin-2|Lymphocyte Culture Test, Mixed|Cytokines|Antibodies, Monoclonal|Receptors, Interleukin-2|Signal Transduction|Transferrin Receptor 2164 CD71 32279324 Clin. Exp. Immunol. 2020 PMC7290081 10.1111/cei.13437 1 0 0 4117 Pregnancy|Humans|Child|Female|Mice|Animals|Adult|*Maternal Age|*T-Cell Subsets|*Labor, Obstetric|Obstetric Labor, Premature|Decidua|Immunophenotyping|Premature Birth|Adaptive Immunity|Cytokines|Dystocia 2164 CD71 32277709 Eur. J. Immunol. 2020 10.1002/eji.201948177 0 0 0 4117 Humans|*IgA|*T Cells|CD71 antigen|Receptors, Transferrin|Antigens, CD|Secretory IgA|Immunoglobulin Isotypes|DC-specific ICAM-3 grabbing nonintegrin|Receptors, Cell Surface|Lectins, C-Type|Cell Adhesion Molecules|Monocyte|*Isoforms|Dendritic Cells 2164 CD71 32267290 Braz Oral Res 2020 10.1590/1807-3107bor-2020.vol34.0033 0 0 0 4117 Humans|*Stem Cells|CD71 antigen|Receptors, Transferrin|Antigens, CD|Keratinocytes|NGFR protein, human|Receptors, Nerve Growth Factor|Cell Separation|Integrin alpha6|Nerve Tissue Proteins|Cell Differentiation|Cells, Cultured|Flow Cytometry|*Phenotype|Oral Mucosa 2164 CD71 32229108 Hematol Transfus Cell Ther 2020 10.1016/j.htct.2020.01.005 0 0 0 4117 *Induced Pluripotent Stem Cells|*Hematopoietic Stem Cells|Pluripotent Stem Cells|Antigens, CD34|Cell Differentiation|Cell Disease, Sickle|*Erythrocytes, Abnormal|Hematopoietic Stem Cell Transplantation|*Mutation 2164 CD71 32172064 Biomed. Pharmacother. 2020 10.1016/j.biopha.2020.110062 0 0 0 4117 Humans|Female|Mice|Cattle|Animals|*Tumor Microenvironment|*Disease Models, Animal|*Triple-Negative Breast Cancer|AC protocol|*Doxorubicin|*Antineoplastic Combined Chemotherapy Protocols|*Cyclophosphamide|Cell Line, Tumor|CD8-Positive T-Lymphocytes 2164 CDCA7 32574680 Virus Res. 2020 10.1016/j.virusres.2020.198064 0 0 0 92 Swine|Animals|*RNA, Micro|Influenza A Virus, H1N1 Subtype|Transmissible gastroenteritis virus|Virus Replication|*Antiviral Agents|Type I Interferon|Host-Pathogen Interactions|Upregulation|Cell Line 50 CDCA7 32533820 Endocr Metab Immune Disord Drug Targets 2020 10.2174/1871530320666200613204426 0 0 0 92 Humans|Immunodeficiency syndrome, variable|*Immunologic Deficiency Syndromes|*Primary Immunodeficiency Diseases|*Centromeres|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|*Face|CDCA7 protein, human|Nuclear Proteins|Mutations|Chromosomal Instability|Agammaglobulinemia|Repressor Proteins|*Musculoskeletal Abnormalities|HELLS protein, human|DNA Helicases|ZBTB24 protein, human 50 CDCA7 32360517 Clin. Immunol. 2020 10.1016/j.clim.2020.108453 0 0 0 92 Humans|Mice|Animals|*Severe Combined Immunodeficiency|DNA methyltransferase 3B|*DNA (Cytosine-5-)-Methyltransferases|Immunologic Deficiency Syndromes|Immunodeficiency syndrome, variable|Primary Immunodeficiency Diseases|CDCA7 protein, human|Nuclear Proteins|Centromeres|*Mice, SCID|Face|DNA Helicases|Chromosomal Instability|Mutation|Repressor Proteins|DNA Methylation|Genes, cdc|HELLS protein, human 50 CDCA7 32319649 Mol Med Rep 2020 PMC7248471 10.3892/mmr.2020.11089 0 0 0 92 Humans|*Colorectal Cancer|Prognosis|CDCA7 protein, human|*Nuclear Proteins|Lymphatic Metastasis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Upregulation|Cell Movement|Cell Proliferation|*Neoplastic Processes|*Colonic Neoplasms|Disease Progression|Cell Line, Tumor|Survival Rate|RNA, Messenger 50 CDCA7 32221746 J. Cancer Res. Clin. Oncol. 2020 10.1007/s00432-020-03194-x 0 0 0 92 Neoplasm Recurrence, Local|*Lung Adenocarcinoma|*Cancer Stem Cell|Lung Neoplasms|Adenocarcinoma|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Gene Expression Profiling|*Correlation of Data|RNA, Messenger 50 CDCA7 32178558 Cell Cycle 2020 PMC7217375 10.1080/15384101.2020.1731052 0 0 0 92 Mice|Animals|*Carcinoma, Hepatocellular|*RNA, Long Noncoding|EZH2 protein, human|*Enhancer of Zeste Homolog 2|*Liver Neoplasms|Mice, Nude|CEBPB protein, human|*CCAAT-Enhancer-Binding Protein-beta|Gene Expression Regulation, Neoplastic|LEF1 protein, human|Lymphoid Enhancer-Binding Factor 1|MicroRNAs|Cell Proliferation|Upregulation|Downregulation|Cell Line, Tumor|Lef1 protein, mouse|Cebpb protein, mouse 50 CDH16 32527043 Cells 2020 10.3390/cells9061435 0 0 0 53 Rats|Animals|*Intrauterine Growth Retardation|Diabetes Mellitus, Type 2|histone H3 trimethyl Lys4|Histone|Epigenesis, Genetic|Modifications, Histone|Chromatin Immunoprecipitation|Promoter Regions, Genetic|Chromosome Mapping|Transcriptome|Transcription Factors 48 CDH16 32194432 Front Physiol 2020 PMC7063463 10.3389/fphys.2020.00139 0 0 0 53 Humans|Rats|Animals|*Acute Kidney Injury|*Sepsis|*Biomarkers|*Urinalysis|Cecum|Early Diagnosis|Proteomics|Ligation|Disease Models, Animal 48 CDH16 31920382 Cancer Manag Res 2020 PMC6934283 10.2147/CMAR.S229631 0 0 0 53 Humans|*Thyroid Cancer, Papillary|*Down-Regulation|Thyroid Cancer|Carcinoma, Papillary|Lymphatic Metastasis|Carcinoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Reverse Transcriptase Polymerase Chain Reaction 48 CDH19 32296631 Front Oncol 2020 PMC7137378 10.3389/fonc.2020.00330 0 0 0 36 Humans|*Prognosis|*Computational Biology|*Artificial Intelligence|Disease-Free Survival|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Kaplan-Meier Estimate|Nomogram|*Algorithms|Cell Transformation, Neoplastic 25 CDHR1 32646556 Ophthalmol Retina 2020 10.1016/j.oret.2020.02.009 0 0 0 33 Humans|*Cone-Rod Dystrophies|*Fundus Oculi|*Retinitis Pigmentosa|Lipofuscin|Fluorescein Angiography|*Retinal Cone Photoreceptor Cells|Retinal Pigment Epithelium|Ophthalmoscopy|Macular Degeneration|Tomography, Optical Coherence|Optical Imaging 34 CDHR1 32277948 Clin. Chim. Acta 2020 10.1016/j.cca.2020.04.006 0 0 0 33 Humans|*Codon, Nonsense|*Retinitis Pigmentosa|*Homozygote|Genes, Recessive|*Chinese|Pedigree|Eye Proteins|Exome|Electroretinography|Retina|Mutation|Phenotype|CDHR1 protein, human|Nerve Tissue Proteins|Cadherins 34 CDKL2 32173142 Pathol. Res. Pract. 2020 10.1016/j.prp.2020.152920 0 0 0 100 Humans|*Glioma|Brain Neoplasms|*Disease Progression|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|Prognosis|Gene Expression Regulation, Neoplastic|Immunohistochemistry|mRNA 20 CDNF 32631936 J. Neurosci. 2020 10.1523/JNEUROSCI.2636-19.2020 0 0 0 99 Humans|Male|*Dopamine|Dopaminergic Neurons|Oxidopamine|Nerve Growth Factors|Parkinson Disease|Brain|Neurotransmitter 99 CDNF 32508943 Evid Based Complement Alternat Med 2020 PMC7244963 10.1155/2020/1818307 0 0 0 99 Rats|Animals|*Parkinson Disease|*Endoplasmic Reticulum Stress|Substantia Nigra|Tyrosine Hydroxylase|Dopamine|Rotenone|Glial Cell Line-Derived Neurotrophic Factor 99 CDNF 32394962 Neural Regen Res 2020 10.4103/1673-5374.282262 0 0 0 99 Animals|Rats|*Dopamine|*Neural Stem Cells|*Cell Differentiation|*Hypoxia|Neurons|Nerve Growth Factors|Cells, Cultured|Apoptosis|Brain|Cell Proliferation 99 CDNF 32154930 J. Comp. Neurol. 2020 10.1002/cne.24901 0 0 0 99 *Dopamine|*Gastrointestinal Transit|Enteric Nervous System|Myenteric Plexus|Tyrosine Hydroxylase|Glial Cell Line-Derived Neurotrophic Factor|SLC6A3 protein, human|Dopamine Transporter|*Intestine, Small|Dopaminergic Neurons|Glia|*Neurogenesis|Brain|Cells, Cultured|Fibrinogen 99 CDY1 32470319 Cell Chem Biol 2020 10.1016/j.chembiol.2020.05.007 0 0 0 6 Male|Humans|Histone|Lysine|Chromatin|Chromosomal Proteins, Non-Histone|Polycomb-Group Proteins|Amino Acid Sequence|Methylation|Protein Binding|Drosophila Proteins|Crystallography, X-Ray|Models, Molecular|Sequence Homology, Amino Acid 54 CEBPE 32582178 Front Immunol 2020 PMC7292210 10.3389/fimmu.2020.01089 0 0 0 172 Humans|Infant, Newborn|*IL 12|*Signal Transduction|CD8-Positive T-Lymphocytes|CD28 Antigens|Interleukin-2|Lymphocyte Activation|*Protein Binding|Cells, Cultured 144 CEBPE 32574725 Neurobiol. Dis. 2020 10.1016/j.nbd.2020.104972 0 0 0 172 Humans|Aged|*Pedigree|*Longevity|Phenotype|*Genomics|Exome|Sequence Analysis, DNA|Genetic Variation|Utah 144 CEBPE 32299910 J. Biol. Chem. 2020 PMC7247317 10.1074/jbc.RA120.012366 0 0 0 172 Humans|Neutropenia, Severe Congenital, Autosomal Recessive 3|Neutropenia|Leukocyte Elastase|Granulocyte Colony-Stimulating Factor|Neutrophils|Unfolded Protein Response|Mutation|Congenital Bone Marrow Failure Syndromes 144 CECR2 32356653 Biochemistry 2020 10.1021/acs.biochem.0c00159 0 0 0 63 *Nucleosomes|*Histones|*Acetylation|Chromatin|*Protein Domains|*Protein Processing, Post-Translational|Binding Site|Lysine|Transcription Factors|Protein Binding|*Isoforms|*Magnetic Resonance Imaging|Activation, Transcriptional|Gene Expression Regulation 32 CECR2 32321240 J. Med. Chem. 2020 10.1021/acs.jmedchem.0c00021 0 0 0 63 Histone|*Protein Domains|ATPase|DNA-Binding Proteins|Nuclear Proteins|Transcription Factors|Protein Binding|Binding Sites|Cell Cycle Proteins|Lysine|Acetylation|ATPases Associated with Diverse Cellular Activities|Protein Processing, Post-Translational|Molecular Dynamics Simulation 32 CECR2 32219823 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.04.010 0 0 0 63 Pregnancy|Humans|Female|Screening, Prenatal|*Genetic Testing|Chromosome Disorders|*Chromosome 22|*Fetuses|Karyotyping|Chromosome Deletion|Chromosome Aberrations|In Situ Hybridization, Fluorescence|DNA Copy Number Variations 32 CELF2 32338744 Nucleic Acids Res. 2020 PMC7261192 10.1093/nar/gkaa295 0 0 0 220 Humans|*Heterogeneous-Nuclear Ribonucleoprotein Group C|*RNA Splicing|HNRNPAB protein, human|*Heterogeneous-Nuclear Ribonucleoprotein Group A-B|CELF Proteins|Alternative Splicing|mRNA|Exons|Jurkat Cells|Nerve Tissue Proteins|CELF2 protein, human 85 CELF2 32324763 PLoS ONE 2020 PMC7179890 10.1371/journal.pone.0231639 0 0 0 220 IL10 protein, human|*Interleukin-10|Macrophages|Lipopolysaccharides|MicroRNAs|Cytokines|Anti-Inflammatory Agents|Suppressor of Cytokine Signaling Proteins|Signal Transduction|*RNA-Binding Proteins 85 CELF2 32271415 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202003_20662 0 0 0 220 *Carcinoma, Hepatocellular|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinase|*Phosphatidylinositol 3-Kinases|*Liver Neoplasms|*Downregulation|*Disease Progression|Cell Proliferation|Cell Line, Tumor|Cell Movement|Gene Expression Regulation, Neoplastic|Signal Transduction|Apoptosis 85 CELF4 31913118 Elife 2020 PMC7299348 10.7554/eLife.50491 0 0 0 34 Mice|Animals|*Spiral Ganglion|*Cochlea|*Neurons|Glia|Evoked Potentials, Auditory, Brain Stem|*Transcriptome Analysis 43 CELSR2 32387340 Toxicol. Appl. Pharmacol. 2020 10.1016/j.taap.2020.115030 0 0 0 105 Animals|Humans|*MCF-7 Cells|Molecular Docking Simulation|HEK293 Cells|Plastics|1,1-bis(4-hydroxyphenyl)cyclohexane|Benzhydryl Compounds|bisphenol B|bisphenol A|Phenols|*Receptors, Estrogen|Estrogen Receptor alpha|Oestradiol|Endocrine Disruptors|Estrogens|*Gene Expression|Cell Proliferation|Cell Line, Tumor|Downregulation 106 CELSR2 32293343 BMC Cancer 2020 PMC7161135 10.1186/s12885-020-06813-5 0 0 0 105 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Prognosis|CELSR2 protein, human|*Cadherins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 106 CELSR2 32251684 Toxicol. Appl. Pharmacol. 2020 10.1016/j.taap.2020.114995 0 0 0 105 Humans|picene|HEK293 Cells|Plastics|Molecular Docking Simulation|Receptors, Estrogen|*Chrysenes|pyrene|*Pyrenes|Estrogen Receptor alpha|*Gene Expression|*Signal Transduction|MCF 7 Cells|Estrogens|CYP1A1 protein, human|CYP1A1|Polycyclic Aromatic Hydrocarbons|Gene Expression Regulation, Neoplastic|Transcriptional Activation 106 CELSR2 32096754 Endocr Metab Immune Disord Drug Targets 2020 10.2174/1871530320666200225094756 0 0 0 105 Mice|Animals|shenqi|Diabetes Mellitus, Type 2|*Drugs, Chinese Herbal|Hypoglycemic Agents|Diabetes Mellitus, Experimental|Blood Glucose|*Muscle, Skeletal|Phytotherapy 106 CELSR2 31969989 NPJ Genom Med 2020 PMC6965183 10.1038/s41525-019-0109-4 1 0 0 105 Humans|Adult|*Genome-Wide Association Study|*Pharmacogenetics|Low Density Lipoprotein Cholesterol|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Polymorphism, Single Nucleotide|Phenotypes|Cohort Studies 106 celsr3 32257949 Front Oncol 2020 PMC7092636 10.3389/fonc.2020.00340 0 0 0 177 Humans|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*mRNA|*Liver Neoplasms|MIRN195 microRNA, human|*miRNA|*Prognosis|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Upregulation|CHEK1 protein, human|Checkpoint Kinase 1|MIRN497 microRNA, human 78 celsr3 32239765 Am. 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Biol. 2020 10.1007/978-1-0716-0655-1_4 0 0 0 30 Animals|Mice|Humans|*Astrocytes|*Neurons|Neurogenesis|Neural Stem Cells|Cell Differentiation|Cell Transdifferentiation|Nerve Tissue Proteins|Cellular Reprogramming|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Cells, Cultured|Retroviridae|Neurog2 protein, mouse|Cend1 protein, mouse|Membrane Proteins 26 cenpb 32057908 Immunol. Lett. 2020 10.1016/j.imlet.2020.02.005 0 0 0 198 Humans|*Autoantibodies|*Proteomics|*Centromere|*Sclerosis, Systemic|Centromere Protein B|Centromere Protein A|Autoantigens|*Epitopes|Chromosomal Proteins, Non-Histone|Fluorescent Antibody Technique, Indirect|*Scleroderma, Localized|Arthritis, Rheumatoid|DNA-Binding Proteins|Enzyme-Linked Immunosorbent Assay|Biomarkers 183 CFDP1 32432658 Biosci. Rep. 2020 PMC7284322 10.1042/BSR20194012 0 0 0 43 Animals|Cattle|Humans|Mice|Rats|*Chromatin Assembly and Disassembly|HEK293 Cells|Chromatography, Liquid|Tandem Mass Spectrometry|*Western Blot|Amino Acid Sequence|Retroelements|Phosphoproteins|Chromosomes|Sequence Alignment|Cfdp1 protein, mouse|Extracellular Matrix Proteins|*Transcription Factors|Phosphorylation|Gene Expression|Sequence Homology, Amino Acid|Drosophila|CFDP1 protein, human 40 CFDP1 31917787 PLoS Genet. 2020 PMC6975560 10.1371/journal.pgen.1008538 0 0 0 43 Humans|Genome-Wide Association Study|Endothelial Cells|TWIST1 protein, human|*Twist-Related Protein 1|*Nuclear Proteins|Smooth Muscle Cells|Artery, Coronary|Quantitative Trait Loci|Coronary Artery Disease|Binding Sites|Allele|*Vascular Diseases|Cells, Cultured|Signal Transduction|Protein Binding|Genomics 40 CFDP1 31917448 J. Natl. Cancer Inst. 2020 10.1093/jnci/djz246 2 0 0 43 Humans|Genome-Wide Association Study|*Transcriptome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Pancreatic Cancer|Quantitative Trait Loci|Genotype 40 CFDP1 31891614 PLoS ONE 2020 PMC6938334 10.1371/journal.pone.0227072 0 0 0 43 *Barrett Esophagus|Genome-Wide Association Study|*Quantitative Trait Loci|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Oesophageal Mucosa|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Study, Genetic Association|Case-Control Studies|Esophagogastric Junction|Risk Factors 40 chd2 32609087 Elife 2020 10.7554/eLife.55775 0 0 0 105 Animals|*Autistic Disorder|*Homeostasis|Drosophila Proteins|Drosophila melanogaster|Presynaptic Terminals|Synaptic Transmission|Neuronal Plasticity|Signal Transduction|*Mutation 145 chd2 32598477 Blood Adv 2020 10.1182/bloodadvances.2019001350 0 0 0 105 Humans|Adult|*Lymphoma, Mantle-Cell|Bayes Theorem|Neoplasm Recurrence, Local|*Mutations|CCND1 protein, human|Cyclin D1|NOTCH2 protein, human|Receptor, Notch2|KMT2A protein, human|Histone-Lysine N-Methyltransferase|B Cell Lymphoma|Sequencing, Next-Generation|Genes, p16|Protein-Serine-Threonine Kinases|Myeloid-Lymphoid Leukemia Protein 145 chd2 32593896 Epilepsy Res. 2020 10.1016/j.eplepsyres.2020.106398 0 0 0 105 Child|Humans|*Epileptic Syndromes|*Encephalopathy|Spasms, Infantile|Phenotypes|NAV1.2 Voltage-Gated Sodium Channel|KCNQ2 Potassium Channel|Genetic Testing|Genetic Predisposition to Disease|Mutation|Sequencing, Next-Generation|Age of Onset|India 145 chd2 32573645 Org. 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Chem. 2020 10.1039/d0ob01054e 0 0 0 105 *Anilines|Dimethylformamide|Deuterium 145 chd2 32483190 Sci Rep 2020 PMC7264272 10.1038/s41598-020-65839-8 0 0 0 105 Glycolysis|Citric Acid Cycle|Carbon Isotopes|Glucose|Lactic Acid|Magnetic Resonance Spectroscopy|Cancers 145 chd2 32170405 Childs Nerv Syst 2020 10.1007/s00381-020-04558-x 1 0 0 105 Child|Humans|Female|Adolescent|*Lymphohistiocytosis, Hemophagocytic|*Myoclonic Encephalopathy|Epilepsy|Vagus Nerve Stimulation|Epilepsy, Generalized|Refractory Epilepsy|Electroencephalography|*Family|Haploinsufficiency|Mutations|Infections|CHD2 protein, human|DNA-Binding Proteins 145 chd2 32061754 Cancer Lett. 2020 10.1016/j.canlet.2020.02.001 0 0 0 105 Humans|Thymic epithelial tumor|*Thymus Neoplasms|*Sequencing, Next-Generation|*Neoplasms, Glandular and Epithelial|*Genomics|Thymic Carcinomas|Mutation|*Biomarkers, Tumor|KMT2C protein, human|DNA-Binding Proteins|ARID1A protein, human|Transcription Factors|INDEL Mutation|DNA Mismatch Repair|Frameshift Mutation|*Nucleotides|Nuclear Proteins|CHEK1 protein, human 145 chd2 31993582 Epilepsy Behav Rep 2020 PMC6976925 10.1016/j.ebr.2019.100355 0 0 0 105 Adolescent|Humans|*Myoclonic Epilepsy, Juvenile|*Mutation|Electroencephalography|Seizures, Tonic-Clonic|Phenotype|CHD2 protein, human|DNA-Binding Proteins 145 chd2 31914951 BMC Med. Genet. 2020 PMC6950831 10.1186/s12881-019-0946-0 0 0 0 105 Child|Humans|*Chromatin|*Chromatin Assembly and Disassembly|DNA Copy Number Variations|Mutation|Phenotype|DNA-Binding Proteins|Electroencephalography|*Schizophrenia 145 chd2 31904125 Epilepsia 2020 10.1111/epi.16054 0 0 0 105 Humans|*Dravet Syndrome|NAV1.1 Voltage-Gated Sodium Channel|*Epilepsies|CDKL5 deficiency disorder|*Spasms, Infantile|Epilepsy Syndromes|Febrile Seizures|Phenotype|Mutations|*Encephalopathies|Seizures|Syndrome|PCDH19 protein, human|Cadherins 145 chd2 31900031 Epigenetics 2020 10.1080/15592294.2019.1710913 0 0 0 105 *Myelopoiesis|Epigenesis, Genetic|Chromatin|DNA Methylation|Histones|Hematopoiesis|Cell Differentiation|Protein Processing, Post-Translational|Myeloid Cells|Gene Library|Cell Line, Tumor 145 CHD6 32265337 Sci Signal 2020 10.1126/scisignal.aaz3381 0 0 0 261 Humans|Animals|Influenza A Virus, H9N2 Subtype|Influenza A Virus, H7N9 Subtype|*Mitogen-Activated Protein Kinases|Influenza, Human|Receptor, Interferon alpha-beta|Type I Interferons|Mitogen-Activated Protein Kinase p38|STAT1 Transcription Factor|Virus Replication|Phosphorylation|Signal Transduction|Cell Line|CHD6 protein, human|DNA Helicases|Nerve Tissue Proteins 31 CHD6 32231685 Front Genet 2020 PMC7083100 10.3389/fgene.2020.00210 0 0 0 261 Humans|Allele Frequency|Genetics, Population|Linkage Disequilibrium|Genotype|*Genomics|Models, Genetic|*Research Design|Heterozygote|Allele 31 CHI3L2 32666680 Ann Clin Transl Neurol 2020 10.1002/acn3.51114 0 0 0 30 *Amyotrophic Lateral Sclerosis|*Chitinases|Hexosaminidases|Disease Progression|Biomarkers|Case-Control Studies 35 CHI3L2 32611760 Neurol Neuroimmunol Neuroinflamm 2020 10.1212/NXI.0000000000000815 0 0 0 30 Humans|Neurofilament Proteins|Multiple Sclerosis|*Disabled Persons|Biomarkers|Disease Progression|Chitinases 35 CHI3L2 32536900 Front Neurol 2020 PMC7267218 10.3389/fneur.2020.00377 0 0 0 30 Humans|*Amyotrophic Lateral Sclerosis|*Chitinases|chitotriosidase|Hexosaminidases|*Biomarkers|Disease Progression|Spinal Cord|Case-Control Studies|Proteomics|Motor Cortex 35 CHI3L2 32066474 J Neuroinflammation 2020 PMC7025403 10.1186/s12974-020-1723-x 0 0 0 30 *Alzheimer Disease|*Chitinase|*Disease Progression|*Frontal Cortex|Biomarkers|Brain 35 CHI3L2 31993418 Front Cell Dev Biol 2020 PMC6970952 10.3389/fcell.2019.00359 0 0 0 30 35 CHRFAM7A 32638534 2020 10.1002/art.41429 0 0 0 87 *Non-Neuronal Cholinergic System|*Osteoarthritis|*Inflammation|alpha7 Nicotinic Acetylcholine Receptor|Chondrocytes 57 CHRFAM7A 32303780 Inflamm. Res. 2020 PMC7263946 10.1007/s00011-020-01349-7 0 0 0 87 Humans|*Monocytes|alpha7 Nicotinic Acetylcholine Receptor|*Leukocytes|Nicotinic Acetylcholine Receptor|*Cell Movement|Macrophages 57 CHRFAM7A 31898332 Int J Geriatr Psychiatry 2020 10.1002/gps.5260 1 0 0 87 *Lewy Body Disease|Alzheimer Disease|Lewy Bodies|alpha-Synuclein|Parkinson Disease|*Genetic Association Studies|Brain|Biomarkers 57 CILP2 32568739 Aging (Albany NY) 2020 PMC7343441 10.18632/aging.103361 0 0 0 28 Haplotypes|Genetic Association Studies|Gene Frequency|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Genotype|Gene-Environment Interaction|Lipids 34 CISD1 32590339 J. 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Monit. 2020 PMC7291787 10.12659/MSM.921947 0 0 0 191 Humans|*Ferroptosis|*Glioma|*Prognosis|Isocitrate Dehydrogenase|Brain Neoplasms|Mutation|Promoter Regions, Genetic|DNA Methylation|Biomarkers, Tumor|SLC1A5 protein, human|Minor Histocompatibility Antigens|Amino Acid Transport System ASC 84 CISD1 32201986 FASEB J. 2020 PMC7212019 10.1096/fj.201903051R 0 0 0 191 *Mitophagy|*Mitochondrial Dynamics|*AMP-Activated Protein Kinases|parkin protein|*Ubiquitin-Protein Ligases|Carbonyl Cyanide m-Chlorophenyl Hydrazone|Mitochondria|Cell Lines|Parkinson Disease 84 CIZ1 32196604 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202003_20521 0 0 0 143 *RNA, Long Noncoding|*Up-Regulation|*Oncogenes|*Oncogenesis|*Lung Cancer|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Prognosis|Cell Line, Tumor|Apoptosis|*Transcriptional Activation|Disease Progression 70 CIZ1 32088211 Life Sci. 2020 10.1016/j.lfs.2020.117454 1 0 0 143 dihydroartemisinin|*Signal Transduction|*Cell Transformation, Neoplastic|*Artemisinins|*Downregulation|Smad Proteins|Epithelial-Mesenchymal Transition|Transforming Growth Factor beta1|*Tumorigenesis|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|Xenograft Model Antitumor Assays 70 CIZ1 32038460 Front Neurol 2020 PMC6989602 10.3389/fneur.2019.01387 0 0 0 143 70 CKAP2 32420172 Transl Androl Urol 2020 PMC7215026 10.21037/tau.2019.11.24 0 0 0 245 *Computational Biology|Gene Regulatory Networks|Gene Expression Profiling|Gene Ontology|Gene Expression Regulation, Neoplastic|Protein Interaction Maps|Biomarkers, Tumor|Transcriptome 50 CKAP2 32297074 Interdiscip Sci 2020 10.1007/s12539-020-00366-8 0 0 0 245 *Carcinoma, Hepatocellular|*Liver Neoplasms|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Computational Biology|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Transcriptome|*Genetic Markers|Genes, cdc|Signal Transduction|Cell Cycle 50 CKAP2 32264951 Genome Biol. 2020 PMC7333371 10.1186/s13059-020-01990-9 0 0 0 245 *Systems Biology|*Cellular Senescence|Tumor Suppressor Protein p53 50 CLEC11A 32473752 Biochem. 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Genomics 2020 PMC7324877 10.2174/1389202921666200316115631 0 0 0 322 Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Pancreas|Biomarkers, Tumor|Kaplan-Meier Estimate|Chloride Channels 202 CLIC1 32604772 Genes (Basel) 2020 10.3390/genes11060706 0 0 0 322 Humans|*RNA|Alzheimer Disease|*Clinical Dementia Rating|Cognitive Decline|Amyloid beta-Peptides|Neuropsychological Tests|Sensitivity and Specificity|Disease Progression|Biomarkers 202 CLIC1 32586242 Protein Pept. 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Med. 2020 PMC7201926 10.1084/jem.20190971 0 0 0 322 Humans|Mice|Animals|Child|*Medulloblastoma|CLIC1 protein, rat|*Potassium Channel|Drosophila melanogaster|*Chloride Channels|Brain Cancer|Cell Size|Cell Proliferation|RNA Interference|Cell Movement|Cell Line, Tumor|Tumorigenesis|Cell Growth Processes|Cell Transformation, Neoplastic|Mitosis|Cerebellar Neoplasms|CLIC1 protein, human 202 CLIC1 32021665 J Lasers Med Sci 2020 PMC6983861 10.15171/jlms.2019.S1 3 0 0 322 202 CLIC1 31926585 Discov Med 2020 0 0 0 322 *Hepatocellular Carcinoma|dihydroartemisinin|Liver Neoplasms|*Artemisinins|Cell Line, Tumor|Hep G2 Cells|Caspases|Apoptosis|Signal Transduction 202 CLIC4 32667519 Braz Dent J 2020 10.1590/0103-6440202003104 0 0 0 385 *Myofibroblasts|*Tumor Suppressor Protein p53|*Lip|CLIC4 protein, human|*Chloride Channels|*Carcinogenesis|Actinic cheilitis|Cheilitis|Lip Neoplasms|*Transforming Growth Factor|Transforming Growth Factor beta|Carcinoma, Squamous Cell|Keratinocytes|Cytoplasm|Cells, Epithelial|Signal Transduction|Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms 122 CLIC4 32655306 Curr. Genomics 2020 PMC7324877 10.2174/1389202921666200316115631 0 0 0 385 Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Pancreas|Biomarkers, Tumor|Kaplan-Meier Estimate|Chloride Channels 122 CLIC4 32550557 Gene X 2020 PMC7285916 10.1016/j.gene.2020.100031 0 0 0 385 Humans|Mesenchymal Stromal Cells|Bone Marrow Cells|Cell Differentiation|Cells, Cultured|Thy-1 Antigens|NT5E protein, human|5'-Nucleotidase|Fibroblasts|Biomarkers|Cell Proliferation|Antigens, CD|Flow Cytometry|GPI-Linked Proteins 122 CLIC4 32509387 Am J Cancer Res 2020 PMC7269788 0 0 0 385 *Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Radiosensitivity|Carcinoma|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|NOS2 protein, human|Signal Transduction|CLIC4 protein, human|*Chloride Channels|Up-Regulation|*Heavy Ion Radiotherapy|Downregulation|DNA Repair|Reactive Oxygen Species 122 CLIC4 32328183 J Cancer 2020 PMC7171491 10.7150/jca.40850 0 0 0 385 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Prognosis|Transcriptomes|*Cohort Studies|RNA, Messenger|Up-Regulation|Downregulation|*Chinese|China 122 CLIC4 32184265 J. Cell. Sci. 2020 PMC7240295 10.1242/jcs.241117 1 0 0 385 *Cytoskeleton|Cytokinesis|Actomyosin|Actin|Mitosis|Telophase|Microtubules|*Plasma Membrane|Anaphase|Actin Cytoskeleton|CLIC4 protein, human|*Chloride Channels|*Proteolysis|Phosphorylation|*Cell Membrane Structures 122 CLIC4 32145706 FEBS Lett. 2020 10.1002/1873-3468.13766 0 0 0 385 Humans|Animals|DIAPH3 protein, human|*Formins|CLIC4 protein, human|*Channel, Chloride|Actin|Filopodia|*Cytoplasm|Carrier Proteins|Plasma Membrane|Adaptor Proteins, Signal Transducing|HeLa Cells 122 CLIC4 32116799 Front Physiol 2020 PMC7034325 10.3389/fphys.2020.00096 2 0 0 385 Humans|CLIC4 protein, human|*Chloride Channels|*Cytoplasm|Ion Channel|Organelles|Mitochondria|Chlorides|Intracellular Membranes|Cardiomyocyte|*Biomarkers 122 CLIC4 31921386 Oncotarget 2020 PMC6944452 10.18632/oncotarget.27387 0 0 0 385 *Up-Regulation|*Squamous Cell Carcinoma of Head and Neck|Squamous Cell Carcinoma|Gene Expression Regulation, Neoplastic|MicroRNAs|*Disease Progression|Genes, Tumor Suppressor|CLIC4 protein, human|*Chloride Channels|Head and Neck Neoplasms|Gene Expression Profiling|*Neoplasms, Glandular and Epithelial|*Transcriptional Activation|Cell Line, Tumor 122 CLIC5 32655306 Curr. Genomics 2020 PMC7324877 10.2174/1389202921666200316115631 0 0 0 111 Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Pancreas|Biomarkers, Tumor|Kaplan-Meier Estimate|Chloride Channels 55 CLIC5 32568133 Technol Health Care 2020 10.3233/THC-202138 0 0 0 111 *MicroRNAs|*Computational Biology|*Osteosarcoma|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|mRNA|Gene Expression Profiling|Gene Ontology|Oligonucleotide Array Sequence Analysis|Up-Regulation|Signal Transduction|Cell Line, Tumor|Gene Expression 55 CLIC5 32165249 Fish Shellfish Immunol. 2020 10.1016/j.fsi.2020.03.008 0 0 0 111 Animals|*Streptococcus agalactiae|*Oreochromis niloticus|*Transcriptome|*Proteome|*Virulence|Proteomics|DNA Helicases|Poly-ADP-Ribose Binding Proteins|RNA Helicases|RNA Recognition Motif Proteins|Streptococcal Infections|Tilapia|Fish Diseases|Transcriptome Analysis|Aquiculture 55 CLIC5 32120024 Cancer Lett. 2020 10.1016/j.canlet.2020.02.038 0 0 0 111 *Transcriptional Activation|RNA, Long Noncoding|*Carcinoma, Pancreatic Ductal|homeobox protein HOXA13|Homeodomain Proteins|Pancreatic Carcinoma|*Pancreatic Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|Oncogenesis|Cell Line, Tumor|Upregulation|Genes, Homeobox|Cell Cycle|Oncogenes|Disease Progression 55 CLIC5 32116799 Front Physiol 2020 PMC7034325 10.3389/fphys.2020.00096 2 0 0 111 Humans|CLIC4 protein, human|*Chloride Channels|*Cytoplasm|Ion Channel|Organelles|Mitochondria|Chlorides|Intracellular Membranes|Cardiomyocyte|*Biomarkers 55 CLIC6 32655306 Curr. Genomics 2020 PMC7324877 10.2174/1389202921666200316115631 0 0 0 37 Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Pancreas|Biomarkers, Tumor|Kaplan-Meier Estimate|Chloride Channels 21 CLMN 32588211 Eur Radiol 2020 10.1007/s00330-020-06906-6 0 0 0 48 *Thyroid Cancer, Papillary|*Nomograms|*Lymphatic Metastasis|Carcinoma, Papillary|Thyroid Neoplasms|*Ultrasonography|Lymph Nodes|Neck|Risk Factors 29 CLMN 32417679 Lung Cancer 2020 10.1016/j.lungcan.2020.03.027 0 0 0 48 Humans|*Exome|Neoplasm Recurrence, Local|*Whole Exome Sequencing|*Sequencing, RNA|*Lung Neoplasms|*Carcinoid Tumor|*Base Sequence|*Carcinoma, Neuroendocrine|Mutation|*Chromosome Aberrations 29 CLMP 32349233 Polymers (Basel) 2020 PMC7284784 10.3390/polym12051006 0 0 0 63 *Mangifera|*Pectins|*Clindamycin|galacturonic acid|Hexuronic Acids|Microwave|Viscosity|Esterification|*Drug Delivery System|*Food Hypersensitivity 584 CLMP 32278545 J. Pediatr. Surg. 2020 10.1016/j.jpedsurg.2020.03.009 0 0 0 63 Humans|*Congenital Short Bowel Syndrome|Short Bowel Syndrome|Intestine, Small|Coxsackie and Adenovirus Receptor-Like Membrane Protein|*Rare Diseases|Diarrhea|Failure to Thrive 584 CLMP 32176142 Otol. Neurotol. 2020 10.1097/MAO.0000000000002580 0 0 0 63 *Neuroma, Acoustic|Exome|High-Throughput Nucleotide Sequencing|Mutation|Gene Expression Profiling 584 CLMP 32108167 Sci Rep 2020 PMC7046776 10.1038/s41598-020-60339-1 2 0 0 63 *Pectins|*Helianthus|galacturonic acid|Hexuronic Acids|Viscosity|Temperature|*Models, Statistical|*Asteraceae|Esterification|Molecular Weight|Spectroscopy, Fourier Transform Infrared 584 CLN8 32597833 J. Clin. Invest. 2020 10.1172/JCI130955 0 0 0 146 Mice|Animals|*Golgi Complex|*Endoplasmic Reticulum|Batten Disease|Lysosome|Protein Transport|Membrane Proteins|Cell Line|Mutation 130 CLN8 32518749 J Orthop Translat 2020 PMC7270532 10.1016/j.jot.2020.03.013 0 0 0 146 130 CLN8 32430003 J. Biomed. Sci. 2020 PMC7238602 10.1186/s12929-020-00653-y 0 0 0 146 Animals|Ceroid Lipofuscinosis, Neuronal, 10|*Neuronal Ceroid-Lipofuscinoses|*Dictyostelium|*Amoeba|Protozoan Proteins|Membrane Proteins|Mutations|Phenotypes|*Mammals|Cathepsin D 130 CLN8 32348865 Genomics 2020 10.1016/j.ygeno.2020.04.025 0 0 0 146 Humans|*High-Throughput Nucleotide Sequencing|*Exome|*Polymorphism, Single Nucleotide|*Parkinson Disease|*Data Analysis|*INDEL Mutation|Sequencing, Whole Exome|Computational Biology|Mutation 130 CLN8 31982899 Neurosciences (Riyadh) 2020 10.17712/nsj.2020.1.20190103 0 0 0 146 Humans|Child|Ceroid lipofuscinosis, neuronal 8|*Neuronal Ceroid-Lipofuscinoses|Saudi Arabia|Disabled Persons|Motor Disorders|Phenotype|Genotype|Mutation|Membrane Proteins 130 CLPB 32573439 Elife 2020 PMC7343390 10.7554/eLife.55279 0 0 0 384 Humans|Animals|3-Methylglutaconic Aciduria|*Protein, Mitochondrial|*Metabolism, Inborn Errors|Saccharomyces cerevisiae Proteins|ATPase|HSP70 Heat-Shock Proteins|Heat-Shock Proteins|Saccharomyces cerevisiae|*Mutations|Protein Aggregates|Protein Binding|Disorder, Mitochondrial|Mitochondrial Membranes|HAX1 protein, human|Adaptor Proteins, Signal Transducing 563 CLPB 32521667 Microorganisms 2020 10.3390/microorganisms8060865 0 0 0 384 Animals|*Parasites|*Vacuoles|Plasmodium falciparum|*Protein Transport|Protozoan Proteins|Malaria, Falciparum|Erythrocytes|Host-Parasite Interactions 563 CLPB 32471865 J. Biol. Chem. 2020 10.1074/jbc.RA120.014587 0 0 0 384 *Leishmania donovani|*Heat Shock Protein|Leishmaniasis, Visceral|Antiprotozoal Agents|Macrophages|Nitric Oxide 563 CLPB 32392200 Mol. Biol. (Mosk.) 2020 10.31857/S0026898420020196 0 0 0 384 Photobacterium leiognathi|*Molecular Chaperones|Luciferases, Bacterial|Escherichia coli Proteins|Escherichia coli|Endopeptidase Clp|Heat-Shock Proteins|HSP70 Heat-Shock Proteins|HSP40 Heat-Shock Proteins|Protein Refolding|Luciferases|Bacterial Proteins|Adenosine Triphosphatases|Photorhabdus luminescens|Aliivibrio fischeri|Hot Temperature|Photobacterium|Kinetics 563 CLPB 32367315 Mol. Biol. Rep. 2020 10.1007/s11033-020-05472-w 0 0 0 384 *Tobacco|*Thermotolerance|Plants, Genetically Modified|Plant Proteins|Droughts|Gene Expression Regulation, Plant|Stress, Heat|Stress, Physiological|Adaptation, Physiological|Cloning, Molecular|*Cytoplasm|*Protein Isoforms|Ziziphus 563 CLPB 32365846 Pathogens 2020 PMC7280961 10.3390/pathogens9050338 0 0 0 384 563 CLPB 32354351 Microbiome 2020 PMC7193372 10.1186/s40168-020-00837-6 0 0 0 384 Humans|Mice|Animals|*Gastrointestinal Microbiome|*Microbiota|ClpB Chaperone|Obesity|Escherichia coli Proteins|*Biomarkers|*Phenotype|Heat-Shock Proteins|Bacteria 563 CLPB 32292399 Front Microbiol 2020 PMC7118207 10.3389/fmicb.2020.00523 0 0 0 384 563 CLPB 32275693 PLoS Pathog. 2020 PMC7182274 10.1371/journal.ppat.1008466 0 0 0 384 Mice|Animals|*Francisella tularensis|*Virulence|ClpB Chaperone|*Heat-Shock Response|Escherichia coli Proteins|Escherichia coli|HSP70 Heat-Shock Proteins|Heat-Shock Proteins|Type VI Secretion System|Molecular Chaperones|Bacterial Proteins|Cytoplasm|ClpB protein, E coli|dnaK protein, E coli 563 CLPB 32272706 Microorganisms 2020 PMC7232239 10.3390/microorganisms8040530 0 0 0 384 Male|Female|Animals|Rats|*Enterobacteria|*Eating Disorders|Endopeptidase Clp|tripeptide aminopeptidase|*Aminopeptidases|endopeptidase B|*Cysteine Endopeptidases|Escherichia coli Proteins|alpha-MSH|*Starvation|Heat-Shock Proteins|Gastrointestinal Microbiome|Immunoglobulin G|Autoantibodies 563 CLPB 32219827 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.04.014 0 0 0 384 Infant|Humans|Female|3-Methylglutaconic Aciduria|*Metabolism, Inborn Errors|*Genetic Testing|Exome|Endopeptidase Clp|Movement Disorders|Mutation|Cataract 563 CLPB 32127546 Sci Rep 2020 PMC7054433 10.1038/s41598-020-60673-4 0 0 0 384 *Triticum|*Thermotolerance|*Heat-Shock Proteins, Small|Gene Expression Regulation, Plant|Genes, Plant|Plant Proteins|Polyploid|Genome, Plant|Heat Shock Protein|Multigene Family|Stress, Physiological|Cloning, Molecular|Phylogeny 563 CLPB 32101742 Cell Rep 2020 10.1016/j.celrep.2020.01.110 0 0 0 384 *Protein Unfolding|Endopeptidase Clp|Escherichia coli Proteins|ATPase|Escherichia coli|Protein Conformation|Adenosine Triphosphate|Models, Molecular|Molecular Chaperones|*Hydrolases|Hydrolysis|Protein Transport|*Translocation, Genetic 563 CLPB 32047514 Front Genet 2020 PMC6997537 10.3389/fgene.2019.01391 0 0 0 384 Animals|*Geese|*Genome-Wide Association Study|*Lions|*Eggs|Avian Proteins|Sequence Alignment|Single Nucleotide Polymorphisms|Cloning, Molecular|Amino Acid Sequence|Breeding|Phylogeny|RNA, Messenger|China 563 CLPB 32014406 Int. J. Med. Microbiol. 2020 10.1016/j.ijmm.2020.151402 0 0 0 384 Humans|*Mycobacterium tuberculosis|Tuberculosis|*Lactobacillus casei|*Bacillus|Heat Shock Protein|Macrophages|*Firmicutes 563 CLPB 31996849 Nature 2020 10.1038/s41586-020-1964-y 2 0 0 384 Endopeptidase Clp|Escherichia coli Proteins|Heat-Shock Proteins|*Peptides|Escherichia coli|HSP70 Heat-Shock Proteins|Protein Aggregates|Models, Molecular 563 CLPB 31911661 Int J Obes (Lond) 2020 PMC7188665 10.1038/s41366-019-0515-9 4 0 0 384 Mice|Animals|*Mice, Obese|*Appetite|*Hafnia alvei|*Probiotics|Obesity|ClpB protein, E coli|Endopeptidase Clp|Leptin|Escherichia coli Proteins|Heat-Shock Proteins|Eating|Energy Metabolism 563 CLPP 32655606 Front Plant Sci 2020 PMC7324783 10.3389/fpls.2020.00901 0 0 0 482 *Cupressus|*Cupressaceae|*Genome, Plastid|Phylogeny|Evolution, Molecular|Plastid|DNA, Plant|Conifers|Magnoliopsida|Photosynthesis 1115 CLPP 32623486 Curr. Microbiol. 2020 10.1007/s00284-020-02093-1 0 0 0 482 *Xanthomonas campestris|Virulence|Gene Expression Regulation, Bacterial|Virulence Factors|Bacterial Proteins|Mutagenesis, Site-Directed|Endopeptidases|Plant Diseases|Amino Acid Sequence|Brassica|Mutation|Cellulase 1115 CLPP 32615429 Sci. Total Environ. 2020 10.1016/j.scitotenv.2020.140363 0 0 0 482 *Fire|Wildfires|Soil|Forest|*Microbial Community|Soil Microbiology|Biomass|3'-(1-butylphosphoryl)adenosine 1115 CLPP 32605984 mBio 2020 PMC7327170 10.1128/mBio.01006-20 0 0 0 482 *Antibiotic|Clp Protease|*Cell Division|Depsipeptides|Bacterial Proteins|Bacteria|Protein Binding|Proteolysis 1115 CLPP 32605922 J. Biol. Chem. 2020 10.1074/jbc.RA120.012673 0 0 0 482 1115 CLPP 32601970 Breast Cancer Res. Treat. 2020 10.1007/s10549-020-05729-9 0 0 0 482 *Unfolded Protein Response|Receptor, ErbB-2|Mitochondria|Apoptosis|Chaperonin 60|Protein, Mitochondrial 1115 CLPP 32571844 Plant Physiol. 2020 10.1104/pp.20.00136 0 0 0 482 *Mitochondria|Arabidopsis thaliana|Electron Transport Complex I|Cell Nucleus|Gene Expression Regulation, Plant|Clp Protease|Chloroplast|*Homeostasis|Protein Subunits|Protein Biosynthesis 1115 CLPP 32545339 Plants (Basel) 2020 10.3390/plants9060737 0 0 0 482 Humans|*Genome, Chloroplast|*Araceae|Phylogeny|Gene Order|Evolution, Molecular|Chloroplasts|Codon|Genomics|Chromosome Mapping|*Bisexual 1115 CLPP 32512731 Toxins (Basel) 2020 10.3390/toxins12060372 1 0 0 482 *Nitrogen|*Proteomics|PII Nitrogen Regulatory Proteins|Gene Expression Regulation, Bacterial|Cyanobacteria|Amino Acids, Diamino|Bacterial Proteins|Transcription Factors|*Starvation|Amino Acids 1115 CLPP 32467259 Mol. Cell Proteomics 2020 10.1074/mcp.RA120.002082 0 0 0 482 Mice|Animals|*Proteolysis|*Mitochondria, Heart|Proteome|Isotope Labeling|Protein Processing, Post-Translational|Proteomics|Amino Acid Sequence|Mitochondrial Proteins|Mass Spectrometry|protease N|Serine Endopeptidases 1115 CLPP 32461277 mSphere 2020 PMC7253602 10.1128/mSphere.00412-20 0 0 0 482 1115 CLPP 32442436 Biochim Biophys Acta Mol Cell Res 2020 10.1016/j.bbamcr.2020.118744 0 0 0 482 Male|Humans|*Bacillus subtilis|Endopeptidase Clp|Gene Expression Regulation, Bacterial|Adenosine Triphosphatases|*Complement Factor B|Escherichia coli Proteins|Bacterial Proteins|Promoter Regions, Genetic|Serine Endopeptidases|Transcription, Genetic|Stress, Heat|Mutation|Transcription Factors|ClpP protein, human 1115 CLPP 32416745 Microbiology (Reading, Engl.) 2020 10.1099/mic.0.000920 0 0 0 482 1115 CLPP 32399598 Hum. Genet. 2020 10.1007/s00439-020-02176-w 0 0 0 482 Humans|Female|Gonadal dysgenesis XX type deafness|*mtDNA|*Gonadal Dysgenesis, 46,XX|*Hearing Loss, Sensorineural|Peroxisomal Multifunctional Protein-2|Exome|*Peroxisomal Disorder|Pedigree|*Base Sequence|*Mitochondria|Homozygote|Amino Acyl-tRNA Synthetases|Primary Ovarian Insufficiency|Mitochondrial Proteins|Endopeptidase Clp|Mutation|Phenotype|*Chromosome Mapping 1115 CLPP 32386322 J. Infect. Dis. 2020 10.1093/infdis/jiaa251 0 0 0 482 Mice|Animals|*Staphylococcus aureus|*Staphylococcus Aureus Pneumonia|Endopeptidase Clp|Gene Expression Regulation, Bacterial|Virulence|Neutrophils|*Hydrolases|Proteolysis 1115 CLPP 32342250 Neurogenetics 2020 PMC7283203 10.1007/s10048-020-00609-2 0 0 0 482 Humans|Mice|Animals|Child|Moyamoya disease 1|*Moyamoya Disease|Endothelial Cells|ATPase|Ubiquitin-Protein Ligases|Genetic Predisposition to Disease|*Mitochondria|Mutations|*Genes, Regulator|*Transcription Factor|TFAM protein, human|DNA-Binding Proteins|Mitochondrial Proteins|RNF213 protein, human|ClpP protein, human|Endopeptidase Clp|LONP1 protein, human|ATP-Dependent Proteases 1115 CLPP 32313240 Nat. Struct. Mol. Biol. 2020 10.1038/s41594-020-0409-5 2 0 0 482 *Proteolysis|Endopeptidase Clp|*Protein Unfolding|Escherichia coli Proteins|Escherichia coli|Adenosine Triphosphatases|Protein Conformation|Models, Molecular|Adenosine Triphosphate|Serine Endopeptidases|Protomers 1115 CLPP 32300856 Appl. Microbiol. Biotechnol. 2020 10.1007/s00253-020-10597-w 0 0 0 482 Corynebacterium crenatum|Endopeptidase Clp|Gene Expression Regulation, Bacterial|Escherichia coli Proteins|Adenosine Triphosphatases|Molecular Chaperones|Bacterial Proteins|*Corynebacterium|Amino Acid Sequence|ATPases Associated with Diverse Cellular Activities|Serine Endopeptidases|Heat-Shock Response|*Energy Metabolism 1115 CLPP 32245967 Nat Commun 2020 PMC7125159 10.1038/s41467-020-15516-1 1 0 0 482 pyrazinoic acid|*Pyrazinamide|aspartate 4-decarboxylase|*Carboxy-Lyases|Mycobacterium tuberculosis|Antitubercular Agents|Tuberculosis|Drug Resistance, Bacterial|Microbial Sensitivity Tests|Coenzyme A|Bacterial Proteins 1115 CLPP 32227372 Mol. Microbiol. 2020 10.1111/mmi.14504 0 0 0 482 Mice|Animals|*Borrelia burgdorferi|*Virulence|Sigma Factor|B. burgdorferi Infection|Gene Expression Regulation, Bacterial|Bacterial Proteins|Antigens, Bacterial|Bacterial Outer Membrane Proteins|Lipoprotein 1115 CLPTM1L 32594352 Mol. Neurobiol. 2020 10.1007/s12035-020-01979-2 0 0 0 70 Humans|*Glioblastoma|*Nuclear Respiratory Factor 1|*Astrocytoma|Temozolomide|Brain Neoplasms|NFIB protein, human|*NFI Transcription Factors|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Brain|Prognosis|NDEL1 protein, human|Carrier Proteins|NSUN2 protein, human|Methyltransferases|NAT10 protein, human|N-Terminal Acetyltransferase E 151 CLPTM1L 32576588 Cancer Genomics Proteomics 2020 10.21873/cgp.20202 0 0 0 70 Humans|*Polymorphism, Single Nucleotide|*Telomere|Genetic Predisposition to Disease|Telomerase|*Leukocytes|Neoplasm Proteins|Membrane Proteins|Case-Control Studies|TNKS2 protein, human|Tankyrases 151 CLPTM1L 32380304 Environ Int 2020 10.1016/j.envint.2020.105762 0 0 0 70 *Telomere|*Leukocytes|Telomerase|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Neoplasm Proteins|Genotype|Membrane Proteins|Case-Control Studies|*Metals 151 CLPTM1L 31969372 Cancer Epidemiol. Biomarkers Prev. 2020 10.1158/1055-9965.EPI-19-1281 0 0 0 70 *Esophageal Cancer|Genetic Predisposition to Disease|Genetic Variation|Risk Factors 151 CLPTM1L 31935503 Gene 2020 10.1016/j.gene.2020.144357 0 0 0 70 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|Genome-Wide Association Study|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Telomerase|Neoplasm Proteins|Membrane Proteins|Case-Control Studies|TERT protein, human|CLPTM1L protein, human 151 CLPTM1L 31917448 J. Natl. Cancer Inst. 2020 10.1093/jnci/djz246 2 0 0 70 Humans|Genome-Wide Association Study|*Transcriptome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Pancreatic Cancer|Quantitative Trait Loci|Genotype 151 CLSTN2 32557100 Biol Trace Elem Res 2020 10.1007/s12011-020-02241-5 0 0 0 215 Pregnancy|Female|Animals|Mice|*Weaning|*Hippocampus|Memory|Maze Learning|Synapses|Brain|Animals, Newborn|Prenatal Exposure Delayed Effects|Cerebral Cortex 32 CLSTN2 32352830 Neuropsychology 2020 10.1037/neu0000637 0 0 0 215 *Memory, Episodic|Cognition|Neuropsychological Tests|Intracellular Signaling Peptides and Proteins|Alleles|Phosphoproteins|Polymorphism, Single Nucleotide|Genotype|Dementia 32 CLSTN2 32143402 Animals (Basel) 2020 PMC7143297 10.3390/ani10030434 0 0 0 215 Pregnancy|Sheep|Animals|Female|*Litter Size|*Genome-Wide Association Study|Wool|Breeding|Reproduction|*Phenotype|*Sheep, Domestic|Body Weight|Weaning|SNPs 32 CLSTN2 31989062 Noncoding RNA Res 2020 PMC6965516 10.1016/j.ncrna.2019.12.002 0 0 0 215 *RNA, Long Noncoding|MicroRNAs|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Non-Coding RNA|RNA, Messenger|Gene Expression Profiling|Oncogenes|Cell Transformation, Neoplastic|Cancers 32 CMPK2 32323732 Int. J. Mol. Med. 2020 PMC7138263 10.3892/ijmm.2020.4517 0 0 0 29 Humans|Female|Pregnancy|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|cytidylate kinase|*Abortion, Missed|*Nucleoside-Phosphate Kinase|*Downregulation|Lipopolysaccharides|Reactive Oxygen Species|Macrophages|3'-(1-butylphosphoryl)adenosine|Mitochondria|DNA, Mitochondrial|*Complement Factor B|Signal Transduction|Carrier Proteins|Inflammation|NLRP3 protein, human 21 CMPK2 32256005 Bioinformation 2020 PMC7088422 10.6026/97320630015853 0 0 0 29 *Nipah Virus|*RNA-Seq|Phylogeny|Protein Interaction Maps|Gene Expression Profiling|*Genetic Profile|Downregulation|*Whole Exome Sequencing|Gene Expression|Hemorrhagic Fever, Ebola|Up-Regulation|Genomics 21 CMPK2 32232013 Front Cell Infect Microbiol 2020 PMC7083127 10.3389/fcimb.2020.00097 1 0 0 29 Humans|*miRNAs|*mRNA|*RNA, Circular|*Hantaan virus|*RNA-Seq|Endothelial Cells|Sequencing, RNA|Gene Regulatory Networks|Gene Expression Profiling|Gene Ontology|DDX58 protein, human|DEAD Box Protein 58|*Hantavirus Infections|*Whole Exome Sequencing|Signal Transduction|Asia|PARP10 protein, human|Poly(ADP-ribose) Polymerases 21 CMPK2 32203166 Oncogene 2020 10.1038/s41388-020-1266-8 2 0 0 29 Humans|*RNA, Long Noncoding|*Colorectal Cancer|Cell Proliferation|HCT116 Cells|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|*Neoplastic Processes|Upregulation|*Colonic Neoplasms|Signal Transduction|Cell Cycle 21 CMPK2 32183248 Genes (Basel) 2020 PMC7140832 10.3390/genes11030308 0 0 0 29 Chick Embryo|Animals|*Chickens|*Transcriptome|IFIH1 protein, human|*Interferon-Induced Helicase, IFIH1|Influenza in Birds|DDX58 protein, human|DEAD Box Protein 58|*Transcriptome Analysis|DEAD-box RNA Helicases|Interferon-beta|RNA, Double-Stranded|Immunity, Innate|Influenza A virus|Poly I-C|RNA, Viral|Fibroblasts|Cell Line 21 cMYC 32659731 Stem Cell Res 2020 10.1016/j.scr.2020.101895 0 0 0 18710 Humans|*Muscular Dystrophy, Emery-Dreifuss|Leukocytes, Mononuclear|*Induced Pluripotent Stem Cells|Cellular Reprogramming|Sendai virus|Cell Differentiation|Mutation|*Heart Defects, Congenital|LMNA protein, human|Lamin Type A 828 cMYC 32630449 Biomolecules 2020 10.3390/biom10060957 0 0 0 18710 *Extracellular Vesicles|Mesenchymal Stem Cells|*Stem Cells|Cell Senescence|MicroRNAs|Cell Proliferation|*Hypoxia-Inducible Factor 1|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Cell Communication|Cells, Cultured 828 cMYC 32626956 Mol Med Rep 2020 10.3892/mmr.2020.11213 0 0 0 18710 Humans|*Wnt Signaling Pathway|*Up-Regulation|*Curcumin|*Cell Proliferation|*Lung Cancer|MicroRNAs|CCND1 protein, human|Cyclin D1|Gene Expression Regulation, Neoplastic|Carcinoma, Non-Small-Cell Lung|*Catenins|Cell Movement|Cell Line, Tumor|*Transcriptional Activation|Apoptosis 828 cMYC 32626954 Int. J. Mol. Med. 2020 PMC7307818 10.3892/ijmm.2020.4629 0 0 0 18710 Humans|paeonol|*Wnt Signaling Pathway|*Apoptosis|*Colorectal Cancer|*Acetophenones|Cell Proliferation|CCND1 protein, human|Cyclin D1|*Colonic Neoplasms|HCT 116 Cells|*G0 Phase|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Cycle Arrest|beta Catenin|*Catenins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 828 cMYC 32626933 Int. J. Oncol. 2020 PMC7307591 10.3892/ijo.2020.5080 0 0 0 18710 Humans|Female|Neoplasm Recurrence, Local|*Cell Proliferation|FUBP1 protein, human|*DNA-Binding Proteins|*RNA-Binding Proteins|Triple Negative Breast Neoplasms|Apoptosis|Cell Migration|Cell Cycle|Cisplatin|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Downregulation 828 cMYC 32582982 Mol Med Rep 2020 10.3892/mmr.2020.11272 0 0 0 18710 tanshinone|*Wnt Signaling Pathway|Glycogen Synthase Kinase 3|*Abietanes|*Cell Motility|Cell Proliferation|*Cell Differentiation|CCND1 protein, human|Cyclin D1|*Catenins|Apoptosis|Cell Cycle|Cell Line, Tumor 828 cMYC 32582803 Rep Biochem Mol Biol 2020 PMC7275834 0 0 0 18710 Humans|*Thyroid Carcinoma, Anaplastic|abemaciclib|Neoplasm Recurrence, Local|*Aminopyridines|*Benzimidazoles|Thyroid Cancer|Cell Line, Tumor|Apoptosis|Doxorubicin|Gene Expression Regulation, Neoplastic|CDK4 protein, human|Cyclin-Dependent Kinase 4 828 cMYC 32545208 Cancers (Basel) 2020 PMC7353041 10.3390/cancers12061532 0 0 0 18710 Humans|*Tumor Suppressor Protein p53|*Oncogenes|*Oncogenesis|*Cancer|Proto-Oncogenes|Cell Transformation, Neoplastic|Mutations|Proto-Oncogene Proteins c-myc|ras Proteins|Gene Expression Regulation, Neoplastic|Transcription Factors|Telomerase 828 cMYC 32509464 PeerJ 2020 PMC7246033 10.7717/peerj.9202 0 0 0 18710 Mice|Animals|*Pamidronate|*RAW 264.7 Cells|*Chromatography, High Pressure Liquid|Diphosphonates|Osteitis Deformans|TYRP1 protein, human|*Membrane Glycoproteins|Osteoporosis|Signal Transduction|Cancer 828 cMYC 32504365 Mol. Cell. Biochem. 2020 10.1007/s11010-020-03773-z 0 0 0 18710 Humans|Male|*Prostatic Hyperplasia|*Prostate|*Hyperplasia|*Cells, Epithelial|Cells, Stromal|Receptors, Androgen|Cell Proliferation|Testosterone Propionate|Media, Conditioned|Signal Transduction 828 cMYC 32482904 Cold Spring Harb Protoc 2020 10.1101/pdb.top098392 0 0 0 18710 *Immunoblotting|Western Blotting|Antibodies|Antibody Specificity|Antigens|Epitopes|Hemagglutinin|polyvinylidene fluoride|Polyvinyls|Electrophoresis|Peptides|Membrane Protein|Molecular Weight 828 cMYC 32468065 Mol Med Rep 2020 PMC7339722 10.3892/mmr.2020.11158 0 0 0 18710 Humans|*RNA, Long Noncoding|*Stomach Neoplasms|RNA I|*Nicotinamide|*RNA, Bacterial|*Wnt Signaling Pathway|RNA, Micro|SOXC Transcription Factors|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Neoplasm Invasiveness|*Transcription Factors|*Disease Progression|Downregulation|*Catenins|BCL2 protein, human 828 cMYC 32468019 Mol Med Rep 2020 PMC7339516 10.3892/mmr.2020.11186 0 0 0 18710 *Myeloid Differentiation Factor 88|*Prognosis|*Lymphoma, Large B-Cell, Diffuse|*Mutation|*Polymerase Chain Reaction|Central Nervous System Neoplasms|Immunohistochemistry|Cohort Studies 828 cMYC 32461571 Nat Commun 2020 PMC7253414 10.1038/s41467-020-16479-z 0 0 0 18710 Humans|Pregnancy|Female|Mice|Animals|*Epigenome|*Cells, Epithelial|Mammary Glands, Animal|Signal Transduction|Epithelium|Cell Transformation, Neoplastic|*Cell Count 828 cMYC 32454230 Spectrochim Acta A Mol Biomol Spectrosc 2020 10.1016/j.saa.2020.118483 0 0 0 18710 Humans|*Escherichia coli|Gold|Serum Albumin, Bovine|Copper|Metal Nanoparticles|Spectrometry, Fluorescence|Fluorescence|*Amantadine 828 cMYC 32420596 Clin. Sci. 2020 10.1042/CS20200032 0 0 0 18710 Humans|Animals|Mice|*Celiac Disease|*RNA, Micro|Enteropathy-Associated T-Cell Lymphoma|Lymphoma, T-Cell|IL15 protein, human|Interleukin-15|*Cytoskeletal Proteins|Diabetes Mellitus, Type 2 828 cMYC 32385154 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7261133 10.1073/pnas.1921115117 1 0 0 18710 HNRNPK protein, human|*Heterogeneous-Nuclear Ribonucleoprotein K|Immunoglobulin Class Switching|*RNA-Binding Motifs|Somatic Hypermutation, Immunoglobulin|Cytidine Deaminase|*Antibodies|Recombination, Genetic|Mutation|DNA Breaks 828 cMYC 32377720 Int. J. Mol. Med. 2020 PMC7255471 10.3892/ijmm.2020.4593 0 0 0 18710 Humans|*Esophageal Squamous Cell Carcinoma|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Esophageal Neoplasms|Xeroderma Pigmentosum, Complementation Group D|*Xeroderma Pigmentosum|Vascular Endothelial Growth Factor A|*Cell Proliferation|*Signal Transduction|*Cell Cycle|Carcinoma, Squamous Cell|Apoptosis|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Line, Tumor|*Phosphatidylinositols|Cell Movement|Cisplatin 828 cMYC 32370987 Pathol. Res. Pract. 2020 10.1016/j.prp.2020.152973 0 0 0 18710 Humans|*Plasmablastic Lymphoma|*Lymphoma, Large-Cell, Immunoblastic|Plasma Cells|Lymphoma, Large B-Cell, Diffuse|Prognosis|*Clinical Pathology|Oral Cavity|Diagnosis, Differential|HIV Infections 828 cMYC 32353058 PLoS Pathog. 2020 PMC7217479 10.1371/journal.ppat.1008541 0 0 0 18710 *Ubiquitination|Ehrlichia chaffeensis|E3 Ubiquitin Ligase|Infection, E chaffeensis|CCNE1 protein, human|*Oncoproteins|Cyclin E|Cell Cycle Proteins|Host-Pathogen Interactions|Bacterial Proteins|Downregulation|Protein Binding 828 CNDP1 32664451 Int J Mol Sci 2020 10.3390/ijms21144887 0 0 0 125 Mice|Animals|*Anserine|*Carnosine|*Kidney|Diabetic Nephropathies|Dipeptidases|Diabetes Mellitus, Type 2 70 CNDP1 32326243 Cells 2020 PMC7226479 10.3390/cells9041032 0 0 0 125 Humans|Female|Pregnancy|*Insulin|*Diabetes Mellitus, Type 2|Prospective Studies|*Insulin, Regular, Human|Diabetes, Gestational|Glucose Tolerance Test|Fetal Macrosomia|Blood Glucose|Birth Weight|Risk Factors 70 CNDP1 32150446 Am. 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Renal Physiol. 2020 10.1152/ajprenal.00329.2019 0 0 0 125 Humans|*Diabetic Nephropathies|aminoacyl-histidine dipeptidase|Dipeptidases|CNDP1 protein, human|Albuminuria|Diabetes Mellitus, Type 2|*Exercise Training|Blood Glucose|Kidney 70 CNDP1 32111749 In Vivo 2020 PMC7157887 10.21873/invivo.11803 0 0 0 125 Pregnancy|Female|Humans|*Diabetes, Gestational|*Proteomics|*Biomarkers|Tandem Mass Spectrometry 70 CNDP1 31950064 J Diabetes Res 2020 PMC6948305 10.1155/2019/6850628 0 0 0 125 Humans|*Albuminuria|aminoacyl-histidine dipeptidase|Diabetes Mellitus, Type 2|Dipeptidases|Diabetic Nephropathies|Creatinine|Glomerular Filtration Rate 70 cnga3 32423767 Ophthalmology 2020 10.1016/j.ophtha.2020.04.008 0 0 0 111 *Retina|*Retinal Disease|Retinitis Pigmentosa|DNA Mutational Analysis|Peripherins|Eye Proteins|Pedigree|Genetic Testing|*Cohort Studies|Mutation|United Kingdom 221 cnga3 32352493 JAMA Ophthalmol 2020 PMC7193523 10.1001/jamaophthalmol.2020.1032 0 0 0 111 Animals|Achromatopsia 1|*Color Vision Defects|*Retinal Cone Photoreceptor Cells|*Gene Therapy|*Vision|Dependovirus|Cyclic Nucleotide-Gated Cation Channels|Genetic Vectors|Electroretinography|*Gene Targeting|Disease Models, Animal 221 cnga3 32272140 Neuropharmacology 2020 10.1016/j.neuropharm.2020.108087 0 0 0 111 Mice|Animals|Gated Channel, Cyclic-Nucleotide|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Cyclic GMP|Signal Transduction|*Peripheral Nervous System Diseases|Smell|Retina|Ganglia, Dorsal Root|Pain|Cngb1 protein, mouse|Nerve Tissue Proteins 221 cnga3 32270761 Elife 2020 PMC7182431 10.7554/eLife.55370 0 0 0 111 Mice|Animals|Hibernations|Sciuridae|*Hypothalamus|Thermogenesis|*Neurons|Cold Temperature|Body Temperature 221 cnga3 32173907 FASEB J. 2020 PMC7299158 10.1096/fj.201901951RR 0 0 0 111 Animals|Mice|*Gated Channel, Cyclic-Nucleotide|*Ryanodine Receptor Calcium Release Channel|*Up-Regulation|*Retinal Cone Photoreceptor Cells|*Cyclic GMP|*Signal Transduction|Retina|Endoplasmic Reticulum|*Transcriptional Activation|Cell Death|Mice, Knockout 221 cnga3 32108519 Curr. Eye Res. 2020 10.1080/02713683.2020.1737138 0 0 0 111 221 cnga3 31899291 Prog Retin Eye Res 2020 10.1016/j.preteyeres.2019.100827 2 0 0 111 Humans|Leber Congenital Amaurosis|*Retina|Genetic Therapy|Retinal Degeneration|Eye Proteins|Gene Transfer Techniques|Photoreceptor Cells|Philadelphia 221 CNGB3 32559011 J Gene Med 2020 10.1002/jgm.3243 0 0 0 35 Animals|*Wasp Venoms|*Wasp|*Desensitization, Immunologic|Arthropod Venoms|Bee Venoms|Anaphylaxis|Allergens|Immunoglobulin E|*Immunologic Factors 153 CNGB3 32423767 Ophthalmology 2020 10.1016/j.ophtha.2020.04.008 0 0 0 35 *Retina|*Retinal Disease|Retinitis Pigmentosa|DNA Mutational Analysis|Peripherins|Eye Proteins|Pedigree|Genetic Testing|*Cohort Studies|Mutation|United Kingdom 153 CNGB3 32362048 J. Anim. Breed. Genet. 2020 10.1111/jbg.12482 0 0 0 35 Swine|Animals|Poland|*Breeding|*Homozygote|Inbreeding|Genome|Genotype|Genetics, Population|SNPs|Genomics 153 CNGB3 32305965 J Biomed Res 2020 PMC7183301 10.7555/JBR.33.20190056 0 0 0 35 Mice|Animals|Humans|*Retinal Cone Photoreceptor Cells|Achromatopsia 1|Achromatopsia|Cyclic Nucleotide-Gated Cation Channels|*Disease Models, Animal|Genetic Vectors|Genetic Therapy|Retina|Opsins|CNGB3 protein, human 153 CNGB3 32189222 J. Appl. Genet. 2020 PMC7148265 10.1007/s13353-020-00554-8 0 0 0 35 Humans|Animals|Dogs|Amaurosis congenita of Leber, type 2|Leber Congenital Amaurosis|Retinitis Pigmentosa|*Gene Therapy|Achromatopsia 1|Achromatopsia|*Diseases, Canine|Eye Proteins|Mutation|Disease Models, Animal 153 CNGB3 32173907 FASEB J. 2020 PMC7299158 10.1096/fj.201901951RR 0 0 0 35 Animals|Mice|*Gated Channel, Cyclic-Nucleotide|*Ryanodine Receptor Calcium Release Channel|*Up-Regulation|*Retinal Cone Photoreceptor Cells|*Cyclic GMP|*Signal Transduction|Retina|Endoplasmic Reticulum|*Transcriptional Activation|Cell Death|Mice, Knockout 153 CNGB3 32151571 J AAPOS 2020 10.1016/j.jaapos.2019.11.013 0 0 0 35 Humans|Achromatopsia 1|*Color Vision Defects|*Tomography, Optical Coherence|Fovea Centralis|Electroretinography|Retinal Cone Photoreceptor Cells|Cyclic Nucleotide-Gated Cation Channels|Ophthalmoscopy|Visual Acuity|*Nystagmus, Pathologic|CNGB3 protein, human 153 CNGB3 32108519 Curr. Eye Res. 2020 10.1080/02713683.2020.1737138 0 0 0 35 153 CNGB3 31899291 Prog Retin Eye Res 2020 10.1016/j.preteyeres.2019.100827 2 0 0 35 Humans|Leber Congenital Amaurosis|*Retina|Genetic Therapy|Retinal Degeneration|Eye Proteins|Gene Transfer Techniques|Photoreceptor Cells|Philadelphia 153 CNN3 32667904 Aging (Albany NY) 2020 10.18632/aging.103224 0 0 0 296 Humans|Adolescent|Child|calponin|*Osteosarcoma|*Microfilament Proteins|*Calcium-Binding Proteins|Cell Migration|Cell Proliferation|Neoplasm Invasiveness|Cell Line, Tumor|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Cycle Arrest|Signal Transduction|mRNA|Prognosis 39 CNN3 32051425 Sci Rep 2020 PMC7016181 10.1038/s41598-020-58947-y 0 0 0 296 Humans|Female|*Uterine Cervical Neoplasms|calponin|*Microfilament Proteins|*Calcium-Binding Proteins|Cell Movement|Neoplasm Invasiveness|*Oncogene|Cell Proliferation|Prognosis|HeLa Cells|Cervix Uteri|Cell Line, Tumor|RNA, Small Interfering|Signal Transduction|Xenograft|RNA, Messenger 39 CNN3 32024114 J Clin Med 2020 PMC7074309 10.3390/jcm9020392 0 0 0 296 39 CNN3 31992794 Sci Rep 2020 PMC6987178 10.1038/s41598-020-58189-y 0 0 0 296 Humans|Animals|Mice|calponin|*Transcriptional Activation|*Microfilament Proteins|*Calcium-Binding Proteins|*Epithelial Cells|CCN2 protein, human|Connective Tissue Growth Factor|Adaptor Proteins, Signal Transducing|Actin|CDH1 protein, human|E Cadherin|Phosphoproteins|Intracellular Signaling Peptides and Proteins|Trans-Activators|Transcription Factors|Lens, Crystalline|Cell Cycle Proteins|Fibre, Stress 39 CNPY2 31894275 Oncol. Rep. 2020 10.3892/or.2019.7423 0 0 0 91 Humans|*Downregulation|*Lung Adenocarcinoma|Lung Cancer|Prognosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|Adenocarcinoma|Adaptor Proteins, Signal Transducing|Upregulation|CNPY2 protein, human 27 COBLL1 32429378 Life (Basel) 2020 PMC7281126 10.3390/life10050068 0 0 0 74 Pregnancy|Swine|Animals|Female|*Endometrium|Embryo Implantation|Transcriptome|Gene Expression Profiling|Gene Regulatory Networks|Sus scrofa|Uterus 29 COLQ 32187901 Zhonghua Bing Li Xue Za Zhi 2020 10.3760/cma.j.issn.0529-5807.2020.03.012 0 0 0 91 178 COLQ 32087110 Chem. Biol. Interact. 2020 PMC7065271 10.1016/j.cbi.2020.109007 0 0 0 91 Animals|*Acetylcholinesterase|*Torpedo|polyproline|*Peptides|peptide B|*Protein Precursors|Amino Acid Sequence|Collagen|Mass Spectrometry|Trypsin 178 COLQ 32017610 Can. J. Physiol. 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Rep. 2020 PMC7214395 10.1042/BSR20200669 0 0 0 103 Humans|Rats|Mice|Animals|*Phosphatidylinositol 3-Kinases|*Phosphoinositide 3 Kinase|*Proto-Oncogene Proteins c-akt|*Myocytes, Cardiac|MTOR protein, human|*Mammalian Target of Rapamycin|*Signal Transduction|Cardiac Hypertrophy|*Phosphorylation|NPPA protein, human|Atrial Natriuretic Factor|Isoproterenol|Brain Natriuretic Peptide|Myosin Heavy Chain|Carboxypeptidases|mTOR protein, rat 37 CPA4 32030273 J Thorac Dis 2020 PMC6988016 10.21037/jtd.2019.11.25 1 0 0 103 Humans|*Gefitinib|Carcinoma, Non-Small-Cell Lung|*MicroRNAs|Lung Cancers|Drug Resistance, Neoplasm|Quinazolines|Gene Expression Regulation, Neoplastic|Protein Kinase Inhibitors|Cell Line, Tumor 37 CPA4 31927669 Neurogenetics 2020 10.1007/s10048-019-00600-6 0 0 0 103 Humans|*Down-Regulation|Niemann-Pick Disease, Type C|*Autophagy|*Signal Transduction|Intracellular Signaling Peptides and Proteins|*Apoptosis|*Cytoskeleton|*Gene Expression|Oxidative Stress|Genes, Regulator|Neurons|GPNMB protein, human|Membrane Glycoproteins|ACTG2 protein, human|Actins 37 CPA6 32570281 J. Cell. Mol. Med. 2020 10.1111/jcmm.15517 0 0 0 44 *Colitis, Ulcerative|Infliximab|*Biomarkers|Carboxypeptidases A|Receiver Operating Characteristic|DNA Mutational Analysis|extracellular matrix receptor|Receptors, Cell Surface|Epithelial-Mesenchymal Transition|Mucosa|Extracellular Matrix 24 CPEB1 32566012 Oncol Lett 2020 PMC7285857 10.3892/ol.2020.11593 0 0 0 510 *Urinary Bladder Neoplasms|*mRNA|*Binding Protein|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Biomarkers, Tumor|Downregulation|Gene Ontology|Upregulation|Apoptosis|Signal Transduction|Cell Cycle|Disease Progression 208 CPEB1 32354341 J Ovarian Res 2020 PMC7193392 10.1186/s13048-020-00630-x 0 0 0 510 Humans|Female|*Menopause, Premature|*Primary Ovarian Insufficiency|*Cohort Studies|*Chinese|Polymorphism, Single Nucleotide|Transcription Factors|CPEB1 protein, human|mRNA Cleavage and Polyadenylation Factors 208 CPEB1 32170089 Nat Commun 2020 PMC7070028 10.1038/s41467-020-15209-9 0 0 0 510 *Oogenesis|*RNA Binding Protein|Oocytes|mRNA, Maternal|mRNA|mRNA Cleavage and Polyadenylation Factors|Meiosis|Protein Biosynthesis|3' Untranslated Regions|Gene Expression Regulation, Developmental|Cell Cycle Proteins|Transcription Factors|Binding Sites 208 CPEB1 32113875 Arch. Biochem. Biophys. 2020 10.1016/j.abb.2020.108322 0 0 0 510 Humans|*Signal Transduction|Fibroblasts|Hypertrophic Scar|*THP-1 Cells|Transforming Growth Factor beta1|mRNA|Fibrosis|*Macrophage|Cells, Cultured|Blotting, Western|Type I Collagen|RNA, Small Interfering|Inflammation|CPEB1 protein, human|Transcription Factors|mRNA Cleavage and Polyadenylation Factors|CPEB4 protein, human|RNA-Binding Proteins 208 CPEB1 32099983 Sheng Li Xue Bao 2020 0 0 0 510 Mice|Humans|Female|Animals|*Oogenesis|*Ovulation|Oocytes|Ovarian Follicles|Meiosis|Mitogen-Activated Protein Kinases|mRNA, Maternal|Granulosa Cells|Follicle Stimulating Hormone|*Mitogens|Phosphorylation|Signal Transduction Pathway|Gonadotropins|Epidermal Growth Factor|MAP Kinase Signaling System|Mammals|RNA Binding Protein|Cpeb1 protein, mouse 208 CPEB1 32064777 Cancer Med 2020 PMC7163091 10.1002/cam4.2919 1 0 0 510 Humans|Young Adult|Adolescent|Child|*Polyadenylation|*Osteosarcoma|MicroRNAs|Cell Migration|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|Cell Line, Tumor|Genes, Tumor Suppressor|Bone Neoplasms|Disease Progression 208 CPEB1 32054840 Cell Death Dis 2020 PMC7018772 10.1038/s41419-020-2293-7 0 0 0 510 Mice|Animals|*Non-alcoholic Fatty Liver Disease|*AMP-Activated Protein Kinases|*RNAs, Circular|In Situ Hybridization, Fluorescence|MTOR protein, human|*TOR Serine-Threonine Kinases|*Autophagy|PTEN protein, human|*PTEN Phosphohydrolase|Liver|Mice, Inbred C57BL|Signal Transduction|Disease Models, Animal|MicroRNAs|Cpeb1 protein, mouse|Transcription Factors|mRNA Cleavage and Polyadenylation Factors 208 CPEB1 31978946 Biomolecules 2020 PMC7072219 10.3390/biom10020167 0 0 0 510 *mRNA|*Neurons|FMR1 protein, human|Fragile X Mental Retardation Protein|Dendrites|Fragile X Syndrome|Hippocampus|Long-Term Memory|Cells, Cultured 208 CPEB1 31970406 Nucleic Acids Res. 2020 PMC7102970 10.1093/nar/gkaa010 2 0 0 510 Oogenesis|mRNA, Maternal|Oocytes|Meiosis|Messenger RNA|mRNA Cleavage and Polyadenylation Factors|Protein Biosynthesis|Gene Expression Regulation, Developmental|RNA-Binding Proteins|Transcription Factors|Cell Cycle Proteins 208 CPEB1 31889940 Clin Proteomics 2020 PMC6927194 10.1186/s12014-019-9262-0 0 0 0 510 Humans|Female|*Carcinoma, Ovarian Epithelial|*Peptides|Spectrometry, Mass, Electrospray Ionization|Chromatography, Liquid|Tandem Mass Spectrometry|Proteomics|*Ovarian Cancer|Proteins|*Plasma 208 CPEB2 32440535 Sci Adv 2020 PMC7228762 10.1126/sciadv.aax3868 0 0 0 109 *RNA Binding Protein|Polyadenylation|mRNA|3' Untranslated Regions|mRNA Cleavage and Polyadenylation Factors|mRNA Translation|Transcription Factors|Oocytes|Gene Expression Regulation|Cytoplasm|*Organogenesis 40 CPEB2 32319195 Clin Implant Dent Relat Res 2020 10.1111/cid.12911 0 0 0 109 *RNA, Long Noncoding|*Peri-Implantitis|miRNAs|*High-Throughput Nucleotide Sequencing|Gene Regulatory Networks|RNA, Messenger|*Periodontitis 40 CPEB2 32295602 J. Biomed. Sci. 2020 PMC7160907 10.1186/s12929-020-00643-0 0 0 0 109 Mice|Humans|Animals|Infant, Newborn|*Myofibroblasts|*Lung|Pulmonary Alveoli|*Signal Transduction|Bronchopulmonary Dysplasia|Mice, Knockout|RNA Binding Protein|Hyperoxias|Receptor, Platelet-Derived Growth Factor alpha|*Organogenesis|RNA, Messenger|Cell Proliferation|CPEB2 protein, human 40 CPEB2 31971049 J. Recept. Signal Transduct. Res. 2020 10.1080/10799893.2019.1710846 0 0 0 109 40 CPEB3 32653013 J. Exp. Clin. Cancer Res. 2020 10.1186/s13046-020-01637-4 0 0 0 216 *Epithelial-Mesenchymal Transition|*Colorectal Cancer|IL6R protein, human|*Receptors, Interleukin-6|*Signal Transduction|*Macrophages|*Colonic Neoplasms|CPEB3 protein, human|*RNA-Binding Proteins|Tumor Microenvironment|Cell Movement|Cell Line, Tumor|Cell Proliferation 69 CPEB3 32648330 Anim. Sci. J. 2020 10.1111/asj.13416 0 0 0 216 Female|Cattle|Animals|*Cumulus Cells|CPEB3 protein, human|*RNA-Binding Proteins|*Apoptosis|Cell Proliferation|Cell Cycle|Genes, cdc|Reactive Oxygen Species|Membrane Potential, Mitochondrial|Upregulation|RNA, Small Interfering|Downregulation 69 CPEB3 32619199 Aging (Albany NY) 2020 10.18632/aging.103404 0 0 0 216 *Memory|*Synaptic Plasticity|CPEB3 protein, human|*RNA-Binding Proteins|*Learning|Receptors, N-Methyl-D-Aspartate|Hippocampus|PSD95 Protein|Neurons 69 CPEB3 32454494 Pharmacology 2020 10.1159/000506711 0 0 0 216 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Polyadenylation|CPEB3 protein, human|*RNA-Binding Proteins|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Hep G2 Cells|Biomarkers, Tumor 69 CPEB3 32367630 J Gene Med 2020 10.1002/jgm.3212 0 0 0 216 Humans|Female|*Uterine Cervical Neoplasms|CPEB3 protein, human|*RNA-Binding Proteins|MicroRNAs|RNA, Long Noncoding|*Disease Progression|Cell Proliferation|Apoptosis|Cells, Cultured 69 CPEB3 32366381 Mol. Cell. Biol. 2020 PMC7324849 10.1128/MCB.00010-20 0 0 0 216 *Proteasome Endopeptidase Complex|CPEB3 protein, human|*RNA-Binding Proteins|NF-E2-Related Factor 1|Basic-Leucine Zipper Transcription Factors|Gene Expression Regulation|*Protein Processing, Post-Translational|*Complement System Proteins 69 CPEB3 32229518 J. Neurosci. 2020 PMC7178911 10.1523/JNEUROSCI.0013-19.2020 0 0 0 216 Male|Female|Mice|Animals|*Astrocytes|*Psychological Distress|AMPA Receptor|Synaptic Transmission|CPEB3 protein, human|*RNA-Binding Proteins|Excitatory Postsynaptic Potentials|Synapses|Neurons|Hippocampus|Patch-Clamp Techniques|Cerebellum|Glutamate|Cpeb3 protein, mouse 69 CPEB3 32058631 Addict Biol 2020 10.1111/adb.12881 0 0 0 216 Male|Mice|Animals|*Methamphetamine|*Nucleus Accumbens|Central Nervous System Stimulants|Central Nervous System Sensitization|*Neuroplasticity|Motor Activity|Behavior, Animal|miRNA|Cpeb3 protein, mouse|RNA-Binding Proteins 69 CPEB4 32594159 Brain 2020 10.1093/brain/awaa168 0 0 0 206 Humans|Adult|Mice|Animals|*Polyadenylation|*Epilepsy, Temporal Lobe|*mRNA|Seizures|Status Epilepticus|Refractory Epilepsy, Drug|Gene Expression Regulation|Hippocampus|Transcriptome|Disease Models, Animal|Cytoplasm|CPEB4 protein, human|RNA-Binding Proteins 83 CPEB4 32556917 Mol. Cell. Biochem. 2020 10.1007/s11010-020-03778-8 0 0 0 206 Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Ewings Sarcoma|HeLa Cells|*Upregulation|Cell Proliferation|Cell Migration|*Neuroectodermal Tumors, Primitive, Peripheral|Gene Expression Regulation, Neoplastic|MicroRNAs|Epithelial-Mesenchymal Transition|Cell Line, Tumor|*Transcriptional Activation|CPEB4 protein, human|RNA-Binding Proteins|MIRN330 microRNA, human 83 CPEB4 32517870 Biochem. Biophys. Res. Commun. 2020 10.1016/j.bbrc.2020.05.089 0 0 0 206 Mice|Animals|*Osteoclasts|Phosphatidylinositol 3-Kinases|TNFSF11 protein, human|RANK Ligand|NFATC Transcription Factors|Osteoclastogenesis|*RNA Binding Protein|Cell Differentiation|Signal Transduction|Macrophages|Cell Nucleus|Cells, Cultured|Cell Line|Polyadenylation|Cpeb4 protein, mouse 83 CPEB4 32169429 Gastroenterology 2020 10.1053/j.gastro.2020.03.008 0 0 0 206 Mice|Humans|Animals|*Hepatic Stellate Cells|*Glycolysis|*Fibrosis, Liver|Carbon Tetrachloride|Mice, Inbred C57BL|Signal Transduction|Cells, Cultured|PFKFB3 protein, human|Phosphofructokinase-2|CPEB4 protein, human|RNA-Binding Proteins|Cpeb4 protein, mouse 83 CPEB4 32113875 Arch. Biochem. Biophys. 2020 10.1016/j.abb.2020.108322 0 0 0 206 Humans|*Signal Transduction|Fibroblasts|Hypertrophic Scar|*THP-1 Cells|Transforming Growth Factor beta1|mRNA|Fibrosis|*Macrophage|Cells, Cultured|Blotting, Western|Type I Collagen|RNA, Small Interfering|Inflammation|CPEB1 protein, human|Transcription Factors|mRNA Cleavage and Polyadenylation Factors|CPEB4 protein, human|RNA-Binding Proteins 83 CPEB4 31904478 Cancer Lett. 2020 10.1016/j.canlet.2019.12.041 3 0 0 206 *RNA, Long Noncoding|*Osteosarcoma|*Tumorigenesis|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|MicroRNAs|Bone Neoplasms|Cell Proliferation|Cell Movement|Apoptosis|Cell Line, Tumor|Disease Progression|*Macrophages 83 CPVL 32218539 Pediatr. 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Pathog. 2020 10.1016/j.micpath.2020.104242 0 0 0 866 Tembusu virus|Clathrin|*Endocytosis|Dynamin|Virus Internalization|*Cholesterol|Caveolae|CAV1 protein, human|Caveolin 1|RNA, Small Interfering|Cell Line|*Flavivirus|China 1732 CPZ 32387439 Chem. Biol. 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Dyn. 2020 10.1080/07391102.2020.1763200 0 0 0 866 *Isoproterenol|*Chlorpromazine|*Glutathione S Transferase|*Molecular Docking Simulation|*Tamoxifen|Butyrylcholinesterase|Acetylcholinesterase|Cholinesterase Inhibitors|Ligands|*Carbamazepine 1732 CPZ 32347051 Cell J 2020 PMC7211289 10.22074/cellj.2021.6999 0 0 0 866 Rats|Animals|*Multiple Sclerosis|astaxanthine|*Oligodendrocytes|Cuprizone|Demyelinating Diseases|Myelin Sheath|*Xanthophylls|Microglia|Disease Models, Animal 1732 CPZ 32340337 Cells 2020 PMC7226349 10.3390/cells9041057 0 0 0 866 Rats|Dogs|Animals|*Aquaporin 2|*Actins|*Chlorpromazine|*Endocytosis|Clathrin|Protein Transport|Cell Membrane|Madin Darby Canine Kidney Cells|Aquaporin 6|*Actin Cytoskeleton|Kidney 1732 CPZ 32329306 Clin Psychopharmacol Neurosci 2020 PMC7242107 10.9758/cpn.2020.18.2.249 0 0 0 866 Child|Adolescent|Humans|*Attention Deficit Disorder with Hyperactivity|Evoked Potentials, Auditory|Potential, Event-Related|Attention 1732 CPZ 32327675 Sci Rep 2020 PMC7181754 10.1038/s41598-020-63651-y 0 0 0 866 Humans|didemethylchlorpromazine|*Chlorpromazine|Comet Assay|DNA Damage|Ultraviolet Light|Photosensitization|Mutagenesis|Antipsychotic Agents|*Sequencing, Next-Generation|DNA|Photosensitizers 1732 CRISPR 32679613 Reprod. Domest. Anim. 2020 10.1111/rda.13775 0 0 0 0 Swine|Animals|*CRISPR-Cas Systems|Genome Editing|*CRISPR|Animals, Genetically Modified|Nuclear Transfer Techniques|Gene Knockout Techniques|Cloning, Organism|Myostatin|Swine, Miniature|Phenotype|Genome|Breeding|Mutation|Cells, Cultured|China 18754 CRISPR 32679235 Exp. Cell Res. 2020 10.1016/j.yexcr.2020.112178 0 0 0 0 Male|Humans|Mice|Animals|*Sperm Maturation|*Spermatogenesis|Infertility, Male|Spermatozoa|Testis|Knockout Mouse|Fertility|CDC14A protein, human|Phosphoric Monoester Hydrolases 18754 CRISPR 32679098 Curr. Biol. 2020 10.1016/j.cub.2020.06.057 0 0 0 0 Animals|Male|Female|*Aedes|*Ovary|*Virus Replication|*Endogenous Retroviruses|Flavivirus|piRNA|RNA, Viral|Genome, Insect|Insect Virus|DNA, Viral 18754 CRISPR 32679064 Stem Cell Reports 2020 10.1016/j.stemcr.2020.06.015 0 0 0 0 Humans|Animals|Mice|Histone Demethylases|*Promoter Regions, Genetic|Cell Differentiation|Embryonic Stem Cells|Neural Stem Cells|Gene Expression Regulation, Developmental|Neurogenesis|Cells, Cultured|Neurons|UTX protein, human|Nuclear Proteins|Utx protein, mouse 18754 CRISPR 32678161 Sci Rep 2020 10.1038/s41598-020-68616-9 0 0 0 0 Humans|Mice|Animals|*Pancreatitis|*Chymases|Acute Disease|*Mice, Inbred C57BL|Cerulein|Trypsinogen|Chymotrypsin|Pancreas|Trypsin|*Proteolysis|Disease Models, Animal|Severity of Illness Index 18754 CRISPR 32678143 Sci Rep 2020 10.1038/s41598-020-68567-1 0 0 0 0 Humans|Animals|*Genome-Wide Association Study|*CRISPR-Cas Systems|*CRISPR|Zebrafish|Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels|Ivabradine|Heart Rate|Potassium Channels|Animals, Genetically Modified|Bradycardia|Muscle Proteins 18754 CRISPR 32678083 Nat Commun 2020 10.1038/s41467-020-17060-4 0 0 0 0 Humans|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Brain Neoplasms|CD44 protein, human|Hyaluronan Receptors|DNA Methylation|Signal Transduction|Membrane Glycoproteins|Cell Proliferation|*Phenotype|EMP3 protein, human 18754 CRISPR 32678064 Elife 2020 10.7554/eLife.58629 0 0 0 0 *Point Mutation|Plasmodium falciparum|Malaria, Falciparum|Antimalarials|Protozoan Proteins|*Mutation|Antibiotic 18754 CRISPR 32677892 BMC Plant Biol. 2020 10.1186/s12870-020-02545-7 0 0 0 0 *Recombinases|*Homologous Recombination|Gene Editing|CRISPR-Cas Systems|CRISPR|*Plants|DNA End-Joining Repair|Gene Targeting|Genome, Plant|Mutations 18754 CRISPR 32677665 Biochem. 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Acta 2020 10.1016/j.aca.2020.05.017 0 0 0 0 *Clustered Regularly Interspaced Short Palindromic Repeats|*CRISPR-Cas Systems|*Genes, Bacterial|RNA, Guide|Gene Editing|Bacterial Proteins|Biosensor 18754 CRISPR 32674730 Curr Gene Ther 2020 10.2174/1566523220999200716111502 0 0 0 0 Genetic Vectors|*Disorders, Neurological|Genetic Therapy|Gene Transfer Techniques|Parkinson Disease|Huntington Disease|Alzheimer Disease|Lysosomal Storage Disease|Amyotrophic Lateral Sclerosis|Brain 18754 CRISPR 32674364 Cells 2020 10.3390/cells9071690 0 0 0 0 Humans|Animals|*Zebrafish|*Base Pairing|Genome Editing|CRISPR-Cas Systems|RNA, Guide|CRISPR|Endonucleases|Out, Gene Knock|Genome|*Germ Line|Point Mutations|Cytosine 18754 CRISPR 32674290 Int J Mol Sci 2020 10.3390/ijms21144961 0 0 0 0 *Dystroglycans|*Cellular Senescence|*Mitosis|lamin B1|Lamin Type B|Spindles, Mitotic|*Genomic Instability|DNA Damage|Tumor Suppressor Protein p53|Cell Cycle Arrest|Heterochromatin 18754 CRISPR 32674065 Stem Cell Res 2020 10.1016/j.scr.2020.101901 0 0 0 0 Humans|*Cardiomyopathy, Dilated|*CRISPR-Cas Systems|*CRISPR|*Pluripotent Stem Cell|*Mutation|Induced Pluripotent Stem Cells|Cardiomyocytes|Genome Editing|Cardiomyopathies|Heterozygote|RNA Splicing|Cell Differentiation|Phenotype|Cell Line|RNA-Binding Proteins|Calcium 18754 CRISPR 32673909 Environ Int 2020 10.1016/j.envint.2020.105949 0 0 0 0 Swine|Animals|*Porcine epidemic diarrhea virus|deoxynivalenol|Trichothecenes|Coronavirus Infection|Swine Diseases|Diarrhea|Coronavirus|Cell Line|Weaning|Intestine, Small|Epithelial Cells 18754 CRNN 32593390 Artif Intell Med 2020 10.1016/j.artmed.2020.101856 0 0 0 53 *Electrocardiogram|*Neural Networks, Computer|*Arrythmia|Signal Processing, Computer-Assisted|Algorithms|Heart Rate|*Databases, Genetic|*Attention 59 CRNN 32589588 Neural Netw 2020 10.1016/j.neunet.2020.06.015 0 0 0 53 *Heart Sounds|*Neural Networks, Computer|Algorithms|Signal Processing, Computer-Assisted|Acoustic|RAB8A protein, human|*rab GTP-Binding Proteins|*Databases, Genetic 59 CRNN 32316484 Sensors (Basel) 2020 PMC7219070 10.3390/s20082296 0 0 0 53 Animals|Humans|Signal Processing, Computer-Assisted|Algorithms|Computer Simulation|*Research Design|Normal Distribution|Neural Networks, Computer|*Health Services|Knowledge|Databases, Genetic|Researchers|Animal Diseases|Product Labeling|CRNN protein, human|Membrane Proteins|Neoplasm Proteins 59 CRNN 32231161 Sensors (Basel) 2020 PMC7180550 10.3390/s20071883 0 0 0 53 *Neural Networks, Computer|Fourier Transform|Algorithms|Deep Learning|Noise|*Hearing 59 CRNN 32213830 Nutrients 2020 PMC7146369 10.3390/nu12030862 0 0 0 53 *Dermatitis, Atopic|*T-Cell Lymphomas, Cutaneous|*Eczema|Skin|Intermediate Filament Proteins|Immunoglobulin E|S100 Proteins|Skin Neoplasms 59 CRNN 32054588 IEEE Trans Neural Netw Learn Syst 2020 10.1109/TNNLS.2020.2966744 0 0 0 53 Reproducibility of Results|*Neural Networks, Computer|Algorithm|*Databases, Genetic 59 CRNN 31958603 Spectrochim Acta A Mol Biomol 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Humans|*Apoptosis|*Epithelial Cells|*Ultraviolet Rays|Reactive Oxygen Species|Nuclear Factor-Kappab|Lens, Crystalline|pyrrolidine dithiocarbamic acid|Thiocarbamates|Cataract|p38 Mitogen-Activated Protein Kinases|Gene Expression Regulation|Pyrrolidines|N-Acetyl-L-cysteine|Cartilage|CRTAC1 protein, human|Calcium-Binding Proteins 27 CRTAC1 31921517 PeerJ 2020 PMC6944128 10.7717/peerj.8312 0 0 0 35 Humans|*Prognosis|*Glioma|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Risk Factors 27 CRYBB2 32513477 Redox Biol 2020 PMC7327981 10.1016/j.redox.2020.101597 0 0 0 149 Male|Mice|Animals|*Angiotensin II|*Ophthalmic Artery|Muscle, Smooth, Vascular|Actin Cytoskeleton|Actins|Oxidative Stress|Oxidation-Reduction|integrin-linked kinase|Protein-Serine-Threonine Kinases|Signal Transduction|C57BL Mice|*Bioenergetic|*Retina 99 CRYBB2 32498547 Eur J Ophthalmol 2020 10.1177/1120672120926450 0 0 0 149 Humans|beta-Crystallin B Chain|Cataract, Autosomal Dominant|Cataract|Genes, Dominant|DNA Mutational Analysis|Pedigree|Mutation|Phenotype|Genetic Linkage|Genotype|Chinese 99 CRYBB2 32317624 Transl Psychiatry 2020 PMC7174396 10.1038/s41398-020-0791-0 0 0 0 149 Humans|Animals|Mice|*Crystallin|Case-Control Studies|beta-Crystallin B Chain|*Memory|Lens, Crystalline|Mutations|Sensorimotor Gating|Endophenotypes|Cataract|Prepulse Inhibition|Single Nucleotide Polymorphisms|Parvalbumins|Haplotypes|Schizophrenia|Hippocampus 99 CRYGC 32450668 Zhonghua Yan Ke Za Zhi 2020 10.3760/cma.j.cn112142-20200222-00095 0 0 0 132 65 CRYGD 32450668 Zhonghua Yan Ke Za Zhi 2020 10.3760/cma.j.cn112142-20200222-00095 0 0 0 30 154 CRYGD 32148946 J Ophthalmol 2020 PMC7049832 10.1155/2020/7054315 0 0 0 30 Humans|*Coloboma|gamma-Crystallins|*Cataract|*Chinese|*Mutation|DNA Mutational Analysis|Pedigree|*Iris 154 CRYZ 32251641 Lancet Infect Dis 2020 PMC7322558 10.1016/S1473-3099(20)30001-3 0 0 0 488 Adult|Humans|Infant|Child, Preschool|*Rotavirus|*Double-Blind Method|*Rotavirus Vaccines|*Vaccines, Subunit|Antibody Formation|Immunoglobulin G|South Africa 164 Csde1 32170829 Proteomics 2020 10.1002/pmic.201900331 0 0 0 287 Humans|*Cold-Shock Response|*Pancreatic Cancer|*Pancreas|siRNA|mRNA|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Apoptosis|Prognosis|Immunohistochemistry|Binding Protein|Western Blotting|CSDE1 protein, human|DNA-Binding Proteins|RNA-Binding Proteins 66 Csde1 32161113 Life Sci Alliance 2020 PMC7067469 10.26508/lsa.201900632 0 0 0 287 Animals|*miRNAs|Argonaute Proteins|mRNA|RNA Binding Protein|RNA Stability|*Gene Expression|Drosophila Proteins|Drosophila melanogaster|Gene Silencing 66 Csde1 31987048 Cell Commun. Signal 2020 PMC6986143 10.1186/s12964-019-0496-2 0 0 0 287 Humans|RNA-Binding Proteins|DNA-Binding Proteins|RNA, Messenger|Protein Biosynthesis|Transcription Factors|CSDE1 protein, human 66 CSMD1 32617189 PeerJ 2020 PMC7323713 10.7717/peerj.9294 0 0 0 70 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Mutations|*Databases, Genetic|DNA Copy Number Variations|Genome, Human|Genetic Predisposition to Disease|Asian|Genomics|Whole Genome Sequencing|Japan 142 CSMD1 32411801 J Immunol Res 2020 PMC7204091 10.1155/2020/6284960 0 0 0 70 Humans|Female|*Uterine Cervical Neoplasms|*Papillomavirus Infections|CD274 protein, human|*B7-H1 Antigen|*Genome, Human|*Ethnic Groups|Oncogene Proteins, Viral|Papillomaviridae|Human papillomavirus 16|Capsid Proteins|*Genetic Profile|*DNA|China 142 CSMD1 32340176 Cancers (Basel) 2020 PMC7226611 10.3390/cancers12041039 0 0 0 70 Uveal melanoma|*Uveal Neoplasms|*Melanoma|*Sequencing, Next-Generation|Eukaryotic Initiation Factor-1|Ubiquitin Thiolesterase|GTP-Binding Protein alpha Subunits|DNA Mutational Analysis|RNA Splicing Factors|Mutations|GTP-Binding Protein alpha Subunits, Gq-G11|Tumor Suppressor Proteins|Phosphoproteins|DNA Copy Number Variations 142 CSMD1 32315120 Ann Clin Transl Neurol 2020 PMC7261755 10.1002/acn3.51040 0 0 0 70 Humans|*Migraine with Aura|*Migraine|Juvenile Myoclonic Epilepsy|Photosensitive Epilepsy|Pedigree|Phenotypes|*Translocation, Genetic 142 CSMD1 32034058 J. 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Cell 2020 10.1016/j.devcel.2020.05.019 0 0 0 88 Mice|Animals|Cre recombinase|Integrases|FLP recombinase|DNA Nucleotidyltransferases|*Prosencephalon|Mice, Transgenic|Cell Lineage|*Restriction Mapping|Gene Expression Regulation, Developmental|Neurons|Recombination, Genetic|Transcription Factors 128 CUZD1 32035824 Clin Res Hepatol Gastroenterol 2020 10.1016/j.clinre.2019.12.013 1 0 0 24 Cattle|Sheep|Animals|*Crohn Disease|*Paratuberculosis|*Antibodies, Fungal|Colitis, Ulcerative|*Ruminants|Autoantibodies|GPI-Linked Proteins|*Pancreas|Immunoglobulin G|Biomarkers|*Immunologic Tests|Saccharomyces cerevisiae 35 DACT2 32642106 J Thorac Dis 2020 PMC7330378 10.21037/jtd-19-4206 0 0 0 129 *Atrial Remodeling|*Atrial Fibrillation|*Heart Atria|Transforming Growth Factor beta1|Signal Transduction|Fibroblasts|Blotting, Western 53 DACT2 32454406 EBioMedicine 2020 PMC7248430 10.1016/j.ebiom.2020.102792 0 0 0 129 *Whole Exome Sequencing|*Exome|*Retinitis Pigmentosa|Genes, Recessive|Pedigree|Retinal Degeneration|Eye Proteins|Mutation 53 DACT2 31983425 Biochem. 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Cancer Ther. 2020 10.1158/1535-7163.MCT-19-0776 0 0 0 370 Pancreatic Carcinoma|*Pancreatic Neoplasms|Carcinoma, Pancreatic Ductal|*Macrophages|*Macrophage Activation|Cell Migration|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Intracellular Signaling Peptides and Proteins|*Splicings, Alternative|Xenograft Model Antitumor Assays|Protein-Serine-Threonine Kinases 275 DCLK1 32251410 Nat. Chem. Biol. 2020 PMC7246176 10.1038/s41589-020-0506-0 0 0 0 370 Humans|doublecortin protein|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|Neuropeptides|Microtubule-Associated Proteins|Intracellular Signaling Peptides and Proteins|Protein-Serine-Threonine Kinases|Neoplastic Stem Cells|Epithelial-Mesenchymal Transition|Cell Motility|Cell Line, Tumor|DCLK1 protein, human 275 DCLK1 32203220 Br. J. 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Sci. 2020 10.2108/zs190054 0 0 0 278 Sex Determination Processes|Sex Differentiation|Hermaphroditic Organisms|Transcription Factors|Base Sequence|Cloning, Molecular|Gene Expression Regulation, Developmental|Amino Acid Sequence|DNA, Complementary|RNA, Messenger|Phylogeny 715 DMRT1 32268081 Cell Rep 2020 10.1016/j.celrep.2020.03.055 1 0 0 278 Male|Female|Animals|Chick Embryo|*Sex Differentiation|*Chicken|*Transcriptome|*Gonad|Sex Determination Processes|Testis|Transcription Factors|Ovary|Gene Expression Regulation, Developmental|*Embryo, Mammalian 715 DMRT1 32265199 Biol Open 2020 PMC7132775 10.1242/bio.050054 0 0 0 278 Female|Male|Animals|*Oryzias|*Lipid Metabolism|Sex Determination Processes|Hermaphroditic Organisms|Gonads|Phenotype|*Starvation|Transcription Factors 715 DMRT1 32251494 Genet. Mol. Biol. 2020 PMC7198010 10.1590/1678-4685-GMB-2019-0017 0 0 0 278 Male|Female|Mice|Animals|*Tumor Suppressor Protein p53|Tandem Mass Spectrometry|DMRT1 protein|Transcription Factor|Testes|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|Transcriptional Activation|Germ-Line Cells|Gene Expression Regulation, Developmental|Gonads|Ovary|Xenopus laevis|Promoter Regions, Genetic|mRNA|Prkra protein, mouse|RNA-Binding Proteins 715 DMRT1 32222764 Endocrinology 2020 10.1210/endocr/bqaa048 0 0 0 278 Male|Female|Animals|*Zebrafish|11-ketotestosterone|*Hydrocortisone|Spermatogenesis|*Testosterone|*Development, Sexual|Testis|Sex Differentiation|Zebrafish Proteins|*Reproduction|Ovary|Androgens|Oogenesis|Steroid 17-alpha-Hydroxylase 715 DMRT1 32219030 PeerJ 2020 PMC7085895 10.7717/peerj.8801 0 0 0 278 Male|Female|Animals|Flatfishes|Testis|Fish Proteins|DNA Methylation|Ovary|Cloning, Molecular 715 DMRT1 32219017 PeerJ 2020 PMC7085901 10.7717/peerj.8639 1 0 0 278 Animals|*Alternative Splicing|DMRT1 protein|Transcription Factors|Sex Determination Processes|Turtles|Gonads|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Amino Acid Sequence|Temperature 715 DMRT1 32194623 Front Genet 2020 PMC7061903 10.3389/fgene.2020.00133 0 0 0 278 Male|Female|Animals|*Ovary|*Testis|*Turtles|Gene Expression Profiling|Sex Differentiation|Transcriptome|High-Throughput Nucleotide Sequencing|MicroRNAs|Gene Expression Regulation, Developmental 715 DMRT1 32173540 Gene 2020 10.1016/j.gene.2020.144581 0 0 0 278 Male|Female|Animals|*Testis|*Fundulidae|Gonads|*Killifishes|Spermatogenesis|*Self-Fertilizations|Sex Differentiation|Ovary|Sex Determination Processes|Oogenesis|Fish Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Forkhead Box Protein L2|Cloning, Molecular|Hermaphroditism 715 DMRT1 32102677 Stem Cell Res Ther 2020 PMC7045406 10.1186/s13287-020-01600-2 0 0 0 278 Mice|Male|Animals|*Mouse Embryonic Stem Cells|*Sertoli Cells|*Cell Differentiation|Sex Determination Processes|Sex-Determining Region Y Protein|Sex Differentiation|Testis|SOX9 Transcription Factor|Intermediate Mesoderm 715 DMRT1 32099981 Sheng Li Xue Bao 2020 0 0 0 278 Male|Female|Mice|Animals|*Gonads|Sex Determination Processes|Testis|Sex Differentiation|Sex-Determining Region Y Protein|Ovary|*Cell Differentiation|CTNNB1 protein, human|beta Catenin|Wnt4 Protein|Germ Cells|SOX9 Transcription Factor|Forkhead Box Protein L2|Gene Expression Regulation, Developmental|FGFR2 protein, human|Receptor, Fibroblast Growth Factor, Type 2|SOXE Transcription Factors|Embryonic Development 715 DMRT1 32088770 Mar. 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Allergy 2020 10.1111/cea.13669 0 0 0 217 Humans|Child|Cattle|Female|Animals|*Milk Hypersensitivity|Randomized Controlled Trials as Topic|Infant Formula|Food Hypersensitivity|*Hydrolysis|Milk, Human|Protein Hydrolysates|*Food, Formulated|Synapsins 667 EHF 32372436 Cancer Sci. 2020 10.1111/cas.14444 0 0 0 217 Humans|*Activating Transcription Factor-1|EHF protein, human|*Transcription Factors|*Colorectal Carcinoma|*Signal Transduction|Cell Proliferation|Cell Movement|Epithelial-Mesenchymal Transition|*Transforming Growth Factor|*Disease Progression|Gene Expression Regulation, Neoplastic|Transforming Growth Factor beta|Transforming Growth Factor beta1|Cell Line, Tumor|Transcriptional Activation 667 EHF 32349653 J Headache Pain 2020 PMC7189559 10.1186/s10194-020-01111-8 0 0 0 217 *Migraine|Chronic Disease|Headache 667 EHF 32333137 Eur Arch Otorhinolaryngol 2020 10.1007/s00405-020-05973-1 0 0 0 217 Humans|*Otitis Media|*Audiometry, Pure-Tone|Acoustic Impedance Tests|Auditory Threshold|*Inflammation|Hearing Loss, High-Frequency 667 EHF 32289733 Sleep Med Rev 2020 PMC7351609 10.1016/j.smrv.2020.101313 0 0 0 217 Humans|*Polysomnography|*Precision Medicine|Sleep Apnea, Obstructive|Sleep 667 EIF1AY 32461223 Genome Res. 2020 10.1101/gr.261248.120 0 0 0 31 Male|Female|Humans|*Genes, Y-Linked|X Chromosome|Testis|Y Chromosome, Human 26 EIF2AK4 32631303 BMC Pulm Med 2020 PMC7336641 10.1186/s12890-020-01186-8 0 0 0 742 Humans|*Pulmonary Veno-Occlusive Disease|Hypertension, Pulmonary|Familial Primary Pulmonary Hypertension|Phenotype|Mutation|Protein-Serine-Threonine Kinases|Tomography, X-Ray Computed 307 EIF2AK4 32627660 Autophagy 2020 10.1080/15548627.2020.1783119 0 0 0 742 *Autophagy|*Immunity, Innate|Signal Transduction|Beclin-1|Apoptosis Regulatory Proteins|AMP-Activated Protein Kinase|Protein Binding|Nutrients 307 EIF2AK4 32615282 Mol. 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Sci. 2020 PMC7325623 10.1167/iovs.61.2.3 2 0 0 271 Humans|Infant, Newborn|Mice|Animals|Child|*Oxygen|*Vascular Endothelial Growth Factor A|Retinopathy of Prematurity|Retinal Neovascularization|*Pathological Neovascularization|*Vascular Endothelial Growth Factors|Hyperoxia|Retinal Vessels|Mice, Inbred C57BL|Retina|Animals, Newborn|Disease Models, Animal|Membrane Proteins|EMP2 protein, human|Membrane Glycoproteins 97 EMP2 31981014 J. Neurooncol. 2020 PMC7080560 10.1007/s11060-020-03401-2 0 0 0 271 Humans|Adult|*Meningioma|Meningeal Neoplasms|*Neovascularization, Pathologic|Vascular Endothelial Growth Factor A|Brain Neoplasms|*Biomarkers|Membrane Glycoproteins|*Morphogenesis|EMP2 protein, human 97 EMP2 31902309 Vascular 2020 10.1177/1708538119896446 0 0 0 271 Platelet Glycoprotein GPIb-IX Complex|Platelet Aggregation|Platelet|von Willebrand Factor|Platelet Adhesiveness|Platelet Function Tests 97 Emx1 32291328 J. 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Commun. 2020 10.1016/j.bbrc.2020.01.070 0 0 0 107 Mice|Animals|*Mouse Embryonic Stem Cells|Telencephalon|*Cerebral Cortex|Neurons|Cell Differentiation|Homeodomain Proteins|Gene Expression Regulation, Developmental|Dbx1 protein, mouse 206 EN1 32629812 Int J Mol Sci 2020 10.3390/ijms21134638 0 0 0 246 *Dopamine|*Mesencephalon|Dopaminergic Neurons|Tegmental Area, Ventral|Cell Differentiation|Transcription Factors|Embryo, Mammalian|Substantia Nigra|Homeodomain Proteins|Gene Expression Regulation, Developmental 409 EN1 32612655 J Oncol 2020 PMC7313158 10.1155/2020/9235101 0 0 0 246 Humans|Adult|*Glioblastoma|*Transcription Factors|Brain Neoplasms|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Prognosis|MicroRNAs|Sequencing, RNA|Biomarkers, Tumor|Genes, Homeobox|Signal Transduction|FOXD3 protein, human|Forkhead Transcription Factors 409 EN1 32556098 Am. J. Clin. 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Cell 2020 PMC7362310 10.1016/j.molcel.2020.04.034 0 0 0 246 Humans|BRD4 protein, human|*Nuclear Proteins|*Transcription Factor|Cell Cycle Proteins|Triple-Negative Breast Cancer|*Genes, cdc|Transcription, Genetic|*Isoforms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Genes, Homeobox 409 EN1 32399843 Ann Biomed Eng 2020 10.1007/s10439-020-02531-y 0 0 0 246 *Head Protective Devices|Brain Concussion|Craniocerebral Trauma|Accelerations|Bicycling|Kinematics|Traumatic Brain Injuries|Sports|Falls|Equipment Design|Brain 409 EN2 32539763 BMC Cancer 2020 PMC7296936 10.1186/s12885-020-07049-z 0 0 0 265 Humans|Male|*Prostatic Hyperplasia|*Prostate|*Prostate Cancer|Biomarkers, Tumor|Homeodomain Proteins|*Disease Progression|Nerve Tissue Proteins|*Staining 290 EN2 32434869 J. Cell. 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Anat. 2020 10.1111/joa.13150 0 0 0 265 Mice|Animals|*Mice, Knockout|Nerve Tissue Proteins|Homeodomain Proteins|Mice, Inbred C57BL|Cerebral Cortex|Hippocampus|Thalamus|*Thalamic Nuclei|Disease Models, Animal 290 enac 32663837 Pediatr. Res. 2020 10.1038/s41390-020-1061-9 0 0 0 0 Humans|Infant, Newborn|Female|Pregnancy|*Glucocorticoids|*Preterm Infants|*Respiratory Distress Syndrome, Adult|*Respiratory Distress Syndrome, Newborn|Epithelial Sodium Channels|Lung|*Ion Transport|*Pulmonary Edema|*Lung Diseases, Interstitial|Sodium|Blood, Cord|Nasal Mucosa 3344 enac 32662079 J. Cell. 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Technol. 2020 10.1016/j.biortech.2020.123754 0 0 0 0 *Waste Water|*Microalgae|*Sewage|*Biomass|*Coculture Techniques|Photobioreactor|Waste Disposal, Fluid|Chlorella vulgaris|Nitrogen|Biofuels 3344 enac 32639874 Am. J. Physiol., Cell Physiol. 2020 10.1152/ajpcell.00218.2020 0 0 0 0 MARCKS protein, human|*Myristoylated Alanine-Rich C Kinase Substrate|Intracellular Signaling Peptides and Proteins|Membrane Proteins|*Kidney Tubules, Distal|Cell Membrane|Epithelial Sodium Channels|Phosphatidylinositol|Phosphorylation|Signal Transduction|*Synapsins|Calcium|Cell Line 3344 enac 32635900 BMC Dev. Biol. 2020 PMC7341674 10.1186/s12861-020-00220-6 0 0 0 0 Animals|Female|*Ovary|*Drosophila|*Membrane Potentials|*RNA Interference|*Ion Exchange|Oogenesis|*Cytoplasm|Drosophila melanogaster|Ovarian Follicle|*Electrophysiological Phenomena|Ion Transport|Epithelium|Hydrogen-Ion Concentration 3344 enac 32631918 Infect. Immun. 2020 10.1128/IAI.00237-20 0 0 0 0 Animals|Pseudomonas Infections|Pseudomonas aeruginosa|Cystic Fibrosis|Biofilms|Lung|Disease Models, Animal 3344 enac 32630625 Pharmaceutics 2020 10.3390/pharmaceutics12070616 0 0 0 0 *Cystic Fibrosis|CFTR protein, human|Cystic Fibrosis Transmembrane Conductance Regulator|Epithelial Sodium Channels|Ion Transport|Sodium|Chlorides|Mutation|Epithelial Cells 3344 enac 32628540 Am. J. Physiol. Renal Physiol. 2020 10.1152/ajprenal.00204.2020 0 0 0 0 Mice|Animals|*Aldosterone|*Sodium|Epithelial Sodium Channels|Amiloride|Sodium, Dietary|Potassium|Kidney 3344 enac 32616726 Sci Rep 2020 PMC7331693 10.1038/s41598-020-67633-y 0 0 0 0 Mice|Animals|*X-Rays|Cystic Fibrosis|Lung|*Obstructive Lung Disease|*Radiography|*Velocimetry 3344 enac 32606316 Genes Immun. 2020 10.1038/s41435-020-0103-y 0 0 0 0 Humans|*Cystic Fibrosis|COVID-19|severe acute respiratory syndrome coronavirus 2|CFTR protein, human|Cystic Fibrosis Transmembrane Conductance Regulator|Sodium Channels, Epithelial|Mucociliary Clearance|Epithelial Sodium Channel Blockers|Ion Transport|Chlorides|Bicarbonates|Epithelial Cells 3344 enac 32596943 Insect Mol. Biol. 2020 10.1111/imb.12654 0 0 0 0 Animals|Female|*Oviposition|*Drosophila|Drosophila melanogaster|Species Specificity|Biological Evolution|Fruit|*Ion Channel|Reproduction|Europe 3344 enac 32592815 Kidney Int. 2020 10.1016/j.kint.2020.05.050 0 0 0 0 Mice|Rats|Animals|*Cotransporter, Sodium-Chloride|*NG-Nitroarginine Methyl Ester|*Rodents|*Sodium Chloride, Dietary|Blood Pressure|Hypertension|Natriuresis|*Sodium Chloride|Hydrochlorothiazide|Solute Carrier Family 12, Member 3|Kidney Tubules, Distal|Kidney Diseases|Amiloride|Blood Volume 3344 enac 32588239 Cell Biol. Toxicol. 2020 10.1007/s10565-020-09545-1 0 0 0 0 *Smoke|*Smoke Inhalation Injury|Cystic Fibrosis Transmembrane Conductance Regulator|Bronchi|*Tobacco|Respiratory Epithelium|Epithelial Cells|Cell Line|Permeability|Ion Transport 3344 enac 32556536 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. 2020 10.1007/s00360-020-01287-0 0 0 0 0 Animals|*Sodium Chloride, Dietary|*Sodium Chloride|*Gerbillinae|Aquaporin 2|*Water|AVP protein, human|Vasopressins|Water-Electrolyte Balance|Sodium|Arginine Vasopressin|Aldosterone|Kidney|Drinking|*Homeostasis|Neurophysins 3344 enac 32546098 Proc. Biol. Sci. 2020 PMC7329048 10.1098/rspb.2020.0620 0 0 0 0 Animals|*Dinoflagellate|*Nitrogen|*Ammonium|*Plankton|Symbiosis|Anthozoa|Foraminifera|Carbon|Photosynthesis 3344 enac 32506040 Redox Biol 2020 PMC7276446 10.1016/j.redox.2020.101592 0 0 0 0 Humans|Animals|*Epithelial Sodium Channels|*Respiratory Distress Syndrome, Adult|*Haem|Pulmonary Alveoli|*Signal Transduction|Acute Lung Injury|*Ion Transport|Pulmonary Edema|Cell Line|Cells, Cultured|Disease Models, Animal|*Dyspnea 3344 enac 32497506 Neuron 2020 10.1016/j.neuron.2020.05.012 0 0 0 0 *Taste|Taste Buds|Amiloride|Calcium Channels|*Dysgeusia|*Calcium, Dietary|Sodium Chloride|Signal Transduction|Sodium Channel, Epithelial|Homeostasis|*Minerals 3344 enac 32496192 Elife 2020 PMC7308080 10.7554/eLife.56527 0 0 0 0 Cricetinae|Animals|*Acid Sensing Ion Channels|histidylglycine|Cryoelectron Microscopy|Dipeptides|Sodium Channel, Epithelial|Cricetulus|Ion Channel Gating|Binding Sites|Proton|CHO Cells|Crystallography, X-Ray|Hydrogen-Ion Concentration 3344 enho 32636661 Diabetes Metab Syndr Obes 2020 PMC7334037 10.2147/DMSO.S243755 0 0 0 175 Rats|Animals|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|*Diabetes Mellitus, Experimental|*Hyperglycemia|Peptides|Blood Proteins|Lipid Metabolism|Homeostasis 105 enho 32150081 Medicine (Baltimore) 2020 10.1097/MD.0000000000019365 0 0 0 175 Humans|*Coronary Artery Disease|preptin|*Hypertension|*Peptide Fragments|*Insulin-Like Growth Factor II|Coronary Angiography|Single Nucleotide Polymorphisms|Gene Frequency|Genetic Predisposition to Disease|Body Mass Index|Genotype|*Transcription Factors|Case-Control Studies|Risk Factors 105 enho 32012786 Molecules 2020 PMC7036858 10.3390/molecules25030549 0 0 0 175 Peptides|Blood Proteins|Homeostasis 105 ENOSF1 32550916 Theranostics 2020 PMC7295062 10.7150/thno.42110 0 0 0 12 *Kidney Transplantation|Graft Rejection|Transplantation, Homologous|Kidney|ROC Curve|Biomarkers 23 EPB41L4A 32557646 J. 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Dis. 2020 10.1136/annrheumdis-2019-216428 0 0 0 50 Humans|*B-Lymphocytes|*Signal Transduction|Sjogren's Syndrome|EPSTI1 protein, human|*Neoplasm Proteins|NF-kappa B|Lymphocyte Activation|Gene Expression 37 ERAS 32676388 Transl Androl Urol 2020 PMC7354299 10.21037/tau-19-884 0 0 0 201 Humans|Male|*Enhanced Recovery After Surgery|Gastrectomy|Length of Stay|Postoperative Care|Laparoscopy|Postoperative Complications|*Prostatectomy|*Cytoreduction Surgical Procedures 4072 ERAS 32675000 Semergen 2020 10.1016/j.semerg.2020.06.009 0 0 0 201 Humans|COVID-19|severe acute respiratory syndrome coronavirus 2|*SARS-CoV|*Diagnostic Tests, Routine|Coronavirus Infections|Pneumonia, Viral|Betacoronavirus|Pandemics|*Antibodies 4072 ERAS 32674934 Bull Cancer 2020 10.1016/j.bulcan.2020.05.010 0 0 0 201 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Length of Stay|Postoperative Complications|Sarcopenia|Nutritional Status 4072 ERAS 32674557 Ann Coloproctol 2020 10.3393/ac.2020.03.25 0 0 0 201 Humans|*Digestive System Surgical Procedures|*Postoperative Period|Perioperative Care|Length of Stay|Laparoscopy|Postoperative Complications|Colorectal Neoplasms|Recovery of Function|*Inflammation|Guideline Adherence|Treatment Outcome 4072 ERAS 32670568 Perioper Med (Lond) 2020 PMC7346381 10.1186/s13741-020-00153-5 0 0 0 201 Humans|*Analgesics, Opioid|Pain, Postoperative|Pain Management|Length of Stay|Program Evaluation 4072 ERAS 32670413 Therap Adv Gastroenterol 2020 PMC7339084 10.1177/1756284820936542 0 0 0 201 Humans|*C-Reactive Protein|Anastomotic Leak|Gastrectomy|*Efficacy, Clinical|Predictive Value of Tests|Biomarkers|Postoperative Complications 4072 ERAS 32669957 Int J Med Sci 2020 PMC7359387 10.7150/ijms.46403 0 0 0 201 4072 ERAS 32669934 Curr Oncol 2020 PMC7339857 10.3747/co.27.5869 0 0 0 201 Humans|*Gastrointestinal Stromal Tumors|*Cohort Studies|Imatinib|Sunitinib|Pyrimidines|Gastrointestinal Neoplasms|Benzamides|Piperazines|Protein Kinase Inhibitors|Antineoplastic Agents|Pyrroles|Protein-Tyrosine Kinases|Indoles|*Neoplasms, Second Primary|British Columbia 4072 ERAS 32665828 AoB Plants 2020 PMC7333546 10.1093/aobpla/plaa026 0 0 0 201 *Rhizosphere|*Zea mays|*Agriculture|Soil Microbiology|Nitrogen|Plant Roots|Soil|RNA, Ribosomal, 16S|Microbiota 4072 ERAS 32665473 Anesth. Analg. 2020 10.1213/ANE.0000000000004980 0 0 0 201 Adult|Humans|Child|Adolescent|*Enhanced Recovery After Surgery|Analgesics, Opioid|Pain, Postoperative|Pain Management|Length of Stay|Pain Measurement|*Reconstructive Surgery 4072 ERAS 32663914 P R Health Sci J 2020 0 0 0 201 Animals|*Tropical Medicine|School, Medical|Medicine|University|Puerto Rico|Health Facilities|Microscopy|Microscopy, Scanning Tunneling|Histological Techniques|Diagnostic Tests, Routine|Lepidoptera 4072 ERAS 32661696 World J Surg 2020 10.1007/s00268-020-05691-z 0 0 0 201 Humans|Aged|*Stomach Neoplasms|*Frailty|*Patient Discharge|*Gastrectomy|Laparoscopy|Retrospective Studies|Postoperative Complications 4072 ERAS 32660781 J. 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10.3760/cma.j.cn112137-20200119-00127 0 0 0 698 7587 FEV 32629565 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2020 10.3760/cma.j.cn121094-20190927-00419 0 0 0 698 7587 FEV 32613016 ERJ Open Res 2020 PMC7322899 10.1183/23120541.00298-2019 0 0 0 698 Child|Humans|*Bronchoconstriction|*Electromyography|Bronchial Provocation Tests|Asthma, Exercise-Induced|Asthma|Exercise Test|Forced Expiratory Volume|Spirometry 7587 FEV 32612738 World Allergy Organ J 2020 PMC7322185 10.1016/j.waojou.2020.100130 0 0 0 698 Animals|*Asthma|Skin Tests|Allergens|Immunoglobulin E|Mites|East Africa|Africa 7587 FEV 32608790 Huan Jing Ke Xue 2020 10.13227/j.hjkx.201911011 0 0 0 698 cyclam|Iron|*Heterocyclic Compounds|Water Purification|Hydrogen Peroxide|Rhodamines|Waste Water|Water Pollutants, Chemical 7587 FEV 32571140 Otolaryngol Head Neck Surg 2020 10.1177/0194599820932137 0 0 0 698 *Asthma, Aspirin-Induced|*Sinusitis|*Desensitization, Immunologic|Nasal Polyps|Aspirin|Anti-Inflammatory Agents, Non-Steroidal 7587 FEV 32537235 Asthma Res Pract 2020 PMC7285728 10.1186/s40733-020-00058-6 0 0 0 698 Humans|*Asthma|*Exercise 7587 FEV 32536095 Zhonghua Yi Xue Za Zhi 2020 10.3760/cma.j.cn112137-20200211-00245 0 0 0 698 7587 FEV 32536078 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2020 10.3760/cma.j.cn121094-20190529-00162 0 0 0 698 7587 FEV 32524788 Korean J Radiol 2020 PMC7289694 10.3348/kjr.2019.0551 0 0 0 698 Humans|*Bone Density|Republic of Korea|*Chronic Obstructive Pulmonary Disease|Forced Expiratory Volume|*Tomography, X-Ray Computed|Vital Capacity|Lung|*Cohort Studies|Osteoporosis|Thoracic Vertebrae|*Thorax 7587 FEV 32494843 Int Orthop 2020 10.1007/s00264-020-04604-y 0 0 0 698 *Scoliosis|Kyphosis|Thoracic Vertebrae|Spinal Fusion|Retrospective Studies|*Lung|Postoperative Complications|*Respiratory Physiological Phenomena|*Preservation, Biological 7587 FEV 32493318 BMC Med Educ 2020 PMC7271544 10.1186/s12909-020-02092-7 0 0 0 698 Humans|*Writing|Internship and Residency|*Knowledge 7587 FEV 32486559 Zhonghua Jie He He Hu Xi Za Zhi 2020 10.3760/cma.j.cn112147-20190809-00563 0 0 0 698 7587 FEV 32450647 Zhonghua Yi Xue Za Zhi 2020 10.3760/cma.j.cn112137-20200217-00311 0 0 0 698 7587 FEV 32447906 Zhonghua Liu Xing Bing Xue Za Zhi 2020 10.3760/cma.j.cn112338-20200131-00060 0 0 0 698 7587 FEV 32447905 Zhonghua Liu Xing Bing Xue Za Zhi 2020 10.3760/cma.j.cn112338-20200122-00054 0 0 0 698 7587 FEV 32444304 Allergol Int 2020 10.1016/j.alit.2020.04.004 0 0 0 698 Humans|CCL17 protein, human|*Chemokine CCL17|*Chronic Obstructive Pulmonary Disease|*Lung|*Respiratory Physiological Phenomena 7587 FEV 32431104 Diabetes Metab J 2020 10.4093/dmj.2019.0109 0 0 0 698 Republic of Korea|*Cohort Studies|*Diabetes Mellitus|Vital Capacity|*Lung|Forced Expiratory Volume|Spirometry|Risk Factor|Incidence 7587 FEV 32415475 Radiol Med 2020 10.1007/s11547-020-01223-w 0 0 0 698 *Radiosurgery|*Radiotherapy, Intensity-Modulated|Retrospective Studies|Carcinoma, Non-Small-Cell Lung|*Lung|Lung Neoplasms|Radiotherapy Dosage|Dose Fractionation, Radiation|Tomography, Spiral Computed|Treatment Outcome|*Respiratory Physiological Phenomena 7587 FEZF1 32638620 Cell Transplant 2020 10.1177/0963689720925059 0 0 0 89 Humans|*RNA, Long Noncoding|*Stomach Neoplasms|*HMGA2 Protein|*Cancer Stem Cell|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Tumorigenesis|Cell Movement|Cell Line, Tumor|Transcription Factors|Upregulation|MIRN363 microRNA, human 65 FEZF1 32590821 Medicine (Baltimore) 2020 PMC7329120 10.1097/MD.0000000000021019 0 0 0 89 Humans|*Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|RNA, Antisense|Gene Expression Regulation, Neoplastic|Repressor Proteins|Transcription Factors|Biomarkers, Tumor|Up-Regulation 65 FEZF1 32519669 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2020 0 0 0 89 JAK2 protein, human|*Janus Kinase 2|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|*Signal Transducer and Activator of Transcription 2|*Esophageal Neoplasms|*Esophageal Squamous Cell Carcinoma|JAK3 protein, human|*Janus Kinase 3|Long Non-Coding RNA|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|RNA, Antisense|Repressor Proteins|Zinc Fingers 65 FEZF1 32400067 Andrologia 2020 10.1111/and.13594 0 0 0 89 Humans|*Kallmann Syndrome|*Whole Exome Sequencing|DNA Copy Number Variations|Hypogonadism|Mutation|Extracellular Matrix Proteins|Pedigree|DNA Helicases|Nerve Tissue Proteins|Anosmia|DNA-Binding Proteins|Genetic Heterogeneity|Genotype 65 FEZF1 32349744 BMC Pulm Med 2020 PMC7191745 10.1186/s12890-020-1154-6 0 0 0 89 *RNA, Long Noncoding|*Carcinoma, Non-Small-Cell Lung|*Up-Regulation|Lung Neoplasms|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|MicroRNAs|Transcription Factors|Repressor Proteins 65 FEZF1 32308422 Onco Targets Ther 2020 PMC7147627 10.2147/OTT.S235970 0 0 0 89 Humans|Child|Adolescent|*RNA, Long Noncoding|*Cell Proliferation|*Osteosarcoma|*Apoptosis|*Signal Transduction|CXCR4 protein, human|*Receptors, CXCR4|Gene Expression Regulation, Neoplastic|Hepatocellular Carcinoma|MicroRNAs|Cell Movement|Bone Neoplasms|Cell Line, Tumor|Transcription Factors|Colorectal Cancer|Liver Neoplasms|MIRN144 microRNA, human 65 FEZF1 32228826 Zhongguo Fei Ai Za Zhi 2020 PMC7210085 10.3779/j.issn.1009-3419.2020.101.05 0 0 0 89 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Long Non-Coding RNA|RNA, Antisense|Repressor Proteins|Transcription Factors|Cell Proliferation|Tumorigenesis|Gene Expression Regulation, Neoplastic|Upregulation 65 FEZF1 32210625 Cancer Manag Res 2020 PMC7075242 10.2147/CMAR.S240531 0 0 0 89 *RNA, Long Noncoding|*Glioblastoma|*Upregulation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Transcription Factors|*Transcriptional Activation|Oncogene|Repressor Proteins|Cell Line, Tumor|MicroRNAs 65 FEZF1 32196579 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202003_20494 0 0 0 89 Humans|Male|*RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|*Drug Resistance, Neoplasm|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Transcription Factors|*Prostate Cancer|*Autophagy|MIRN25 microRNA, human 65 FEZF1 32135030 J. Cell. Mol. Med. 2020 PMC7171310 10.1111/jcmm.15088 2 0 0 89 Humans|Female|*RNA, Long Noncoding|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Migration|*Disease Progression|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Transcription Factors|Apoptosis|SOX4 protein, human|SOXC Transcription Factors 65 FEZF1 32020063 Br. J. Cancer 2020 PMC7109049 10.1038/s41416-020-0742-9 1 0 0 89 Humans|*RNA, Long Noncoding|Epigenesis, Genetic|*Lung Carcinoma, Non-Small-Cell|Gene Expression Regulation, Neoplastic|Repressor Proteins|Transcription Factors|Cell Proliferation|Cell Movement|Lung Neoplasms 65 FEZF2 32610082 Cell 2020 10.1016/j.cell.2020.06.002 0 0 0 183 Animals|Mice|Humans|*Chromatin|*Telencephalon|Enhancer Elements, Genetic|Promoter Regions, Genetic|Transcription Factors|Gene Expression Regulation|Sequence Analysis, DNA|Genes, Regulator|SLC6A1 protein, human|GABA Plasma Membrane Transport Proteins 109 FEZF2 32601470 Nat. Immunol. 2020 10.1038/s41590-020-0717-2 0 0 0 183 Mice|Animals|*Central Tolerance|APECED protein|Transcription Factor|*Self-Antigens|Gene Expression Regulation|Autoimmunity|T Cells|Epithelial Cells 109 FEZF2 32588450 Ann. Neurol. 2020 10.1002/ana.25833 0 0 0 183 Mice|Humans|Animals|*Amyotrophic Lateral Sclerosis|Superoxide Dismutase-1|Superoxide Dismutase|Motor Neurons|*Disease Models, Animal|*Interneurons|Motor Cortex 109 FEZF2 32082299 Front Immunol 2020 PMC7005006 10.3389/fimmu.2019.03099 0 0 0 183 Animals|*Cell Differentiation|*Epithelial Cells|Thymocytes|APECED protein|Transcription Factors|Self Tolerance|Signal Transduction 109 FGL1 32577166 Oncotarget 2020 PMC7289528 10.18632/oncotarget.27617 0 0 0 118 Humans|Carcinoma, Hepatocellular|*Messenger RNA|Liver Neoplasms|*Transcriptome|*Circulating RNA|Liver Cirrhosis|Liver|Biomarkers, Tumor|RNA, Micro 50 FGL1 31921022 Front Microbiol 2020 PMC6914681 10.3389/fmicb.2019.02836 0 0 0 118 Humans|*Proteomics|Severe Dengue|Dengue|*Biomarkers|ELISA 50 FGL1 31908014 FASEB J. 2020 10.1096/fj.201901925R 0 0 0 118 Mice|Animals|*Obesity|Body Mass Index|Insulin Resistance|Adipose Tissue|Adipocytes|3T3-L1 Cells|Glucose Tolerance Test|Insulin|Fibrinogen 50 fibronogen 31902182 Hinyokika Kiyo 2020 10.14989/ActaUrolJap_65_11_473 0 0 0 0 Male|Humans|Aged, 80 and over|*Prostate Cancer|Prostate-Specific Antigen|Disseminated Intravascular Coagulation|Adenocarcinoma|Lymphatic Metastasis|fibrin fragment D|Fibrin Fibrinogen Degradation Products|Platelet Count 23 FILIP1 32444788 Commun Biol 2020 PMC7244511 10.1038/s42003-020-0982-5 0 0 0 40 FLNC protein, human|*Filamins|*Phosphorylation|Phosphatidylinositol 3-Kinases|Muscle, Skeletal|Muscle Fibers, Skeletal|Myogenesis|Signal Transduction|Protein Binding|Phenotype|Proteomics|Cell Differentiation|Mutation 22 FILIP1 32441533 Syst Biol Reprod Med 2020 10.1080/19396368.2020.1759730 0 0 0 40 Humans|Female|*Prognosis|*Module, Gene|Neoplasm Recurrence, Local|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Cancer Stem Cells|*Ovary|Drug Resistance, Neoplasm|Biomarkers, Tumor|Cell Line, Tumor 22 FILIP1 32411535 PeerJ 2020 PMC7210810 10.7717/peerj.9086 0 0 0 40 *Carcinoma, Non-Small-Cell Lung|*Prognosis|*Carcinoma, Squamous Cell|Lung Cancer|*Disease Progression|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|MicroRNAs|Computational Biology 22 FJX1 32354225 Cancer Biother. 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Food Chem. 2020 10.1021/acs.jafc.0c03163 0 0 0 0 Tandem Mass Spectrometry|*Flavonols|myricetin|Flavonoids|*Glycosylation|kaempferol|Kaempferols|3-methylquercetin|Quercetin|Glycation End Products, Advanced|Molecular Structure|*Hydroxyl Radical|Fluorescence Spectroscopy|Ovalbumin 15679 flavonols 32660180 Zhonghua Gan Zang Bing Za Zhi 2020 10.3760/cma.j.cn501113-20200522-00269 0 0 0 0 15679 flavonols 32651647 Anal Bioanal Chem 2020 10.1007/s00216-020-02798-z 0 0 0 0 *Spectrometry, Mass, Electrospray Ionization|*Flavonoids|Chromatography, Supercritical Fluid|Methanol|*Cosmetics|Chromatography, High Pressure Liquid|Solvents|Drug Contamination|Carbon Dioxide|Stereoisomerism|*Pharmacy|*Health Services 15679 flavonols 32648748 J. Agric. 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Genet. 2020 PMC7071710 10.1186/s12881-020-0991-8 0 0 0 582 Humans|Birt-Hogg-Dube Syndrome|FLCN protein, human|Tumor Suppressor Proteins|Proto-Oncogene Proteins|Chromophobe Renal Cell Carcinoma|Kidney Neoplasms|Spontaneous Pneumothorax|Genes, Tumor Suppressor|Skin Neoplasms|Mutation|Lung|Lung Diseases|Cysts|*Hyperplasia|*Gastrointestinal Tract 367 fluoxetine 32677215 Child Adolesc Ment Health 2020 10.1111/camh.12323 0 0 0 2 Humans|Adolescent|*Suicidal Ideation|*Depression|Suicide, Attempted|Surveys and Questionnaires|Risk Factors 12311 fluoxetine 32676774 Psychopharmacology (Berl.) 2020 10.1007/s00213-020-05535-7 0 0 0 2 Pregnancy|Male|Female|Animals|Rats|Humans|*Fluoxetine|Serotonin Uptake Inhibitors|*Stress, Life|*Aggression|Prenatal Exposure Delayed Effects|Behavior, Animal|Antidepressive Agents|*Men|*Parturition 12311 fluoxetine 32673474 ACS Chem Neurosci 2020 10.1021/acschemneuro.0c00315 0 0 0 2 Mice|Animals|*Corticosterone|*Vorinostat|*Endoplasmic Reticulum Stress|Fluoxetine|Hippocampus|Water Maze Test|Depression|Behavior, Animal|Stress, Psychological|Neurons|Disease Models, Animal|Brain|Motor Activity|DDIT3 protein, human|Transcription Factor CHOP|Cognition 12311 fluoxetine 32667781 ACS Chem Neurosci 2020 10.1021/acschemneuro.0c00352 0 0 0 2 Mice|Animals|*Myelin Sheath|*Depression|RHOA protein, human|*rhoA GTP-Binding Protein|*Hypoxia|rho-Associated Kinases|1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine|Signal Transduction|Oligodendrocytes|Y 27632|Amides|Pulmonary Artery|Pyridines|Cell Differentiation|*Protective Agents 12311 fluoxetine 32667275 Int J Psychiatry Clin Pract 2020 10.1080/13651501.2020.1782433 0 0 0 2 *Serotonin Uptake Inhibitors|*Depressive Disorder, Major|Antidepressants|Citalopram|Venlafaxine Hydrochloride 12311 fluoxetine 32664030 J Affect Disord 2020 10.1016/j.jad.2020.05.053 0 0 0 2 *Depressive Disorder, Major|*Depression|*Amygdala|*Cortex, Prefrontal|Brain Mapping|Functional Magnetic Resonance Imaging|Neural Pathways|Antidepressive Agents|Brain 12311 fluoxetine 32655962 Case Rep Psychiatry 2020 PMC7327602 10.1155/2020/7801953 0 0 0 2 12311 fluoxetine 32652084 Neuropharmacology 2020 10.1016/j.neuropharm.2020.108221 0 0 0 2 Male|Female|Humans|Mice|Animals|*Rett Syndrome|*Methyl-CpG-Binding Protein 2|*Serotonin|*Fluoxetine|*Disease Models, Animal|Mice, Knockout|*Brain|Corpus Striatum|Learning|Hippocampus|*Heterozygote|Cortex, Prefrontal|Mecp2 protein, mouse 12311 fluoxetine 32649937 J Pharm Sci 2020 10.1016/j.xphs.2020.07.003 0 0 0 2 Male|Cattle|Animals|Rats|*Rats, Sprague-Dawley|*Kinetics|perampanel|*Fluoxetine|*Protein Binding|*Plasma Proteins|*Liver|*Biological Transport|*Pyridones|Metabolic Clearance Rate|Albumins|Perfusion|*Plasma|*Biochemical Phenomena|Alpha(1)-Acid Glycoprotein 12311 fluoxetine 32649306 Int J Pharm Compd 2020 0 0 0 2 Humans|*Suspensions|SyrSpend|*Doxycycline|*Tramadol|*Fluoxetine|*Starch|Drug Stability|Drug Compounding|Administration, Oral|Pharmaceutical Vehicles|Chromatography, High Performance Liquid 12311 fluoxetine 32647087 Anat Cell Biol 2020 10.5115/acb.19.217 0 0 0 2 Humans|Male|Female|*Fluoxetine|*Comet Assay|*Depressive Disorder, Major|Antidepressive Agents|Oxidative Stress|Antioxidants|Depression|DNA Damage|Oxidation-Reduction 12311 fluoxetine 32644274 Eur. 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Lett. 2020 10.1016/j.neulet.2020.135232 0 0 0 2 Mice|Animals|*Resveratrol|*GAP-43 Protein|*Serotonin|*Hippocampus|Antidepressive Agents|Depression|Fluoxetine|Stress, Psychological|Corticosterone|Swimming|Antioxidants|Oxidative Stress|Disease Models, Animal|Adenosine Triphosphate 12311 fluoxetine 32620104 BMC Complement Med Ther 2020 PMC7333290 10.1186/s12906-020-03003-5 0 0 0 2 *Melissa|*Lavandula|*Fluoxetine|*Double-Blind Method|*Depression|*Pilot Projects|Phytotherapy|Crocus|Depressive Disorder|Plant Extracts|Treatment Outcome|Asia 12311 fluoxetine 32619442 Horm Behav 2020 10.1016/j.yhbeh.2020.104813 0 0 0 2 Animals|*Serotonin|*Cooperative Behavior|*Dopamine|*Fishes|Social Behavior|Vasotocin|Behavior, Animal|Perciformes 12311 fluoxetine 32616212 Adv. Pharmacol. 2020 10.1016/bs.apha.2020.03.003 0 0 0 2 Humans|*Antidepressants|Esketamine|Ketamine|*Muscarinic Receptor|Scopolamine|Serotonin Uptake Inhibitors|Muscarinic Antagonists|Prefrontal Cortex 12311 fluoxetine 32606699 Neuropsychiatr Dis Treat 2020 PMC7294105 10.2147/NDT.S245166 0 0 0 2 Humans|*Bipolar Disorder|olanzapine-fluoxetine combination|Benzodiazepines|Antidepressants|Quetiapine|Fluoxetine|Antipsychotic Agents|Lurasidone|Depressive Disorder, Major|Drug Therapy, Combination|Ketamine|Drug Combinations 12311 fluoxetine 32600103 Mol Pain 2020 PMC7328215 10.1177/1744806920938237 0 0 0 2 Mice|Animals|*Vibrissae|*Touch|*Serotonin Plasma Membrane Transport Proteins|*Hair Follicle|Merkel Cells|*Sensory Receptor Cells|Afferent Pathways|Mechanotransduction, Cellular|Touch Perception|*Serotonin Uptake Inhibitors|Serotonin|Synapses|Norepinephrine|Mammals 12311 FLVCR2 32369453 J. Clin. 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Genet. 2020 10.1111/cge.13761 0 0 0 41 Humans|Adult|Encephaloclastic Proliferative Vasculopathy|*Hydranencephaly|*Siblings|Hydrocephaly|Brain|Phenotype|Syndrome|Fetuses|Mutations|Vascular Diseases|Receptors, Virus|Membrane Transport Proteins|FLVCR2 protein, human 22 FLVCR2 32204764 Zhongguo Dang Dai Er Ke Za Zhi 2020 0 0 0 41 *N-Myc Proto-Oncogene Protein|*Prognosis|*Neuroblastoma|Gene Amplification|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor 22 FMN1 32277301 Clin. Exp. Nephrol. 2020 10.1007/s10157-020-01884-x 0 0 0 3571 Humans|*Genome-Wide Association Study|*Albuminuria|Japan|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian|Genetic Loci|Genotype|Chronic Kidney Disease|Risk Factor 42 FMN1 32058959 iScience 2020 PMC6997862 10.1016/j.isci.2020.100847 1 0 0 3571 *Osteoporosis|Bone Density|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genomics|Transcriptomes|Gene Expression Profiling|TNFSF11 protein, human|RANK Ligand|Proteomics|Metabolomic|*Biomarkers 42 FMN1 32054832 Nat Commun 2020 PMC7018843 10.1038/s41467-020-14525-4 0 0 0 3571 Humans|*Saccharomyces cerevisiae|*Flavin Mononucleotide|Saccharomyces cerevisiae Proteins|Amyloid beta-Peptides|Alzheimer Disease|*Yeast, Dried|*Amyloidogenic Proteins|Peptide Fragments|*Amyloidosis|*Redox|riboflavin kinase|Phosphotransferases (Alcohol Group Acceptor) 42 FMN1 31937228 Proc. Biol. 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Clin. Exp. 2020 10.1016/j.metabol.2020.154261 1 0 0 864 Mice|Animals|Humans|*Adipokine|*Lipogenesis|*Adipocytes|FN1 protein, human|Fibronectin|Adipose Tissue, Brown|Obesity|3T3-L1 Cells|Transcription Factors|FNDC5 protein, human|FNDC4 protein, human|Proteins|FNDC5 protein, mouse 740 FNDC5 32396989 J. Neurochem. 2020 10.1111/jnc.15039 0 0 0 864 Humans|Aged|*Alzheimer Disease|*Exercise|*Memory|Fibronectins|*Transcription Factors|Brain|Muscle, Skeletal|Neuroprotection|Cognition|FNDC5 protein, human 740 FNDC5 32369414 Am. J. Physiol. Endocrinol. Metab. 2020 PMC7311674 10.1152/ajpendo.00034.2020 0 0 0 864 Rats|Animals|*Adipose Tissue|Muscle, Skeletal|Obesity|*Transcription Factors|Fibronectins|*Hindlimb|*Lower Extremity|FNDC5 protein, rat 740 FNDC5 32364035 J. Int. Med. Res. 2020 PMC7218978 10.1177/0300060519885569 0 0 0 864 Rats|Animals|*Peroxisome Proliferators|*Sitagliptin|Diabetes Mellitus, Type 2|*Muscle, Skeletal|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|*Peroxisome Proliferator-Activated Receptors|Transcription Factors|AMP-Activated Protein Kinases|Fibronectins 740 FNDC5 32360564 Mol. Cell. Endocrinol. 2020 10.1016/j.mce.2020.110840 0 0 0 864 *Transcription Factors|Fibronectins|Muscle, Skeletal|Exercise|Adipose Tissue|Glycosylation 740 FNDC5 32353410 Cell. Signal. 2020 10.1016/j.cellsig.2020.109665 0 0 0 864 Humans|*Multidrug Resistance Protein 1|*Paclitaxel|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|ABCB1 protein, human|*ATP Binding Cassette Transporter, Subfamily B|Drug Resistance, Neoplasm|Cell Line, Tumor|*Transcription Factors|Signal Transduction|Fibronectins|Muscle, Skeletal|FNDC5 protein, human 740 FNDC5 32325455 Obes Facts 2020 PMC7250364 10.1159/000505666 0 0 0 864 *Obesity, Morbid|Obesity|Production, Heat|*Adipocyte|Exercise|Energy Expenditure|Fibronectins|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Transcription Factors|Muscle, Skeletal 740 FNDC5 32308399 Neuropsychiatr Dis Treat 2020 PMC7154038 10.2147/NDT.S237558 0 0 0 864 Animals|*Sirtuin 1|Depressive Disorder, Major|*Hippocampus|Brain-Derived Neurotrophic Factor|Depression|Stress, Psychological|MicroRNAs|Disease Models, Animal 740 FNDC5 32298013 FASEB J. 2020 10.1096/fj.201902860RRR 0 0 0 864 Mice|Animals|*Fibronectin Type III Domain|*Wnt Signaling Pathway|LRP6 protein, human|Low Density Lipoprotein Receptor-Related Protein-6|*Cell Differentiation|beta Catenin|Myogenesis|Wnt Proteins|Myogenin|*Catenins|Myoblasts|Cell Line|FNDC5 protein, mouse|Fibronectins 740 FNDC5 32274395 Rep Biochem Mol Biol 2020 PMC7103079 0 0 0 864 Rats|Animals|*Diabetes Mellitus, Experimental|Muscle, Skeletal|Obesity|Fibronectins|*Transcription Factors|Diabetes Mellitus, Type 2|*Dietary Supplements|Vitamin D|FNDC5 protein, rat 740 FNDC5 32257109 Cell Biosci 2020 PMC7106581 10.1186/s13578-020-00413-3 0 0 0 864 Phosphatidylinositol 3-Kinases|*Signal Transduction|Fibronectins|Adipocytes, White|Obesity|Cell Differentiation|STAT3 protein, human|STAT3 Transcription Factor|Neuroprotective Effects|Muscle, Skeletal 740 FNDC5 32252102 Int J Sports Med 2020 10.1055/a-1100-7118 0 0 0 864 Humans|Uncoupling Protein 1|Adipose Tissue, Brown|Thermogenesis|Adipose Tissue, White|Adipose Tissue, Beige|Energy Expenditure|fibroblast growth factor 21|Fibroblast Growth Factors|Obesity|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Transcription Factors|*Exercise|Mitochondrial Proteins 740 FNIP1 32327294 Urol. Oncol. 2020 10.1016/j.urolonc.2020.03.016 0 0 0 189 Humans|*Tuberous Sclerosis|Angiomyolipoma|Kidney Neoplasms|Birt-Hogg-Dube Syndrome|Chromophobe Renal Cell Carcinoma|MTOR protein, human|TOR Serine-Threonine Kinases|Tumor Suppressor Proteins|Proto-Oncogene Proteins|*HSP90 Heat-Shock Proteins|Cell Transformation, Neoplastic 44 FNIP1 32195250 Front Cell Dev Biol 2020 PMC7063858 10.3389/fcell.2020.00108 0 0 0 189 44 FNIP1 32181500 Eur. J. 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Patterns 2020 10.1016/j.gep.2019.119093 0 0 0 158 Animals|*Zebrafish|*Phylogeny|Zebrafish Proteins|Amino Acid Sequence|Gene Expression Regulation, Developmental|In Situ Hybridization|Animal Fins|Base Sequence|Transcription, Genetic|Forkhead Box Proteins|RNA, Messenger 191 foxd4 32532883 Cold Spring Harb Mol Case Stud 2020 PMC7304358 10.1101/mcs.a005348 0 0 0 58 Humans|Child|Chromosome 9p Deletion Syndrome|*Chromosome Deletion|Chromosome 9, partial trisomy 9p|*Trisomy|*Chromosome 9|Chromosome Duplication|Chromosome Banding|Translocation, Genetic|Karyotyping|Comparative Genomic Hybridization|Abnormalities, Multiple|In Situ Hybridization, Fluorescence|Developmental Disabilities|Karyotype|Chromosome 13 27 foxd4 32509568 Front Oncol 2020 PMC7251179 10.3389/fonc.2020.00595 0 0 0 58 Humans|*Prognosis|*Colorectal Cancer|*Colon Cancer|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Databases, Genetic|Protein Interaction Maps|Computational Biology|Gene Expression 27 foxd4 32487737 Development 2020 PMC7328008 10.1242/dev.184093 0 0 0 58 Mice|Animals|*Transcription Factor|Helix-Loop-Helix Motifs|Basic Helix-Loop-Helix Transcription Factors|Repressor Proteins|TCF Transcription Factors|Transcription Factor 7-Like 1 Protein|Cell Differentiation|*Gene Expression Regulation 27 foxd4 31917260 Gene Expr. Patterns 2020 10.1016/j.gep.2019.119093 0 0 0 58 Animals|*Zebrafish|*Phylogeny|Zebrafish Proteins|Amino Acid Sequence|Gene Expression Regulation, Developmental|In Situ Hybridization|Animal Fins|Base Sequence|Transcription, Genetic|Forkhead Box Proteins|RNA, Messenger 27 FOXE1 32583281 Mol. Biol. Rep. 2020 10.1007/s11033-020-05592-3 0 0 0 257 Humans|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|SMAD4 protein, human|Smad4 Protein|*Mutations|Genes, p16|Exome|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Oncogenes|Transcriptome|Genomics|FOXE1 protein, human|Forkhead Transcription Factors|CNTNAP2 protein, human|Membrane Proteins|Nerve Tissue Proteins 241 FOXE1 32565793 Int J Endocrinol 2020 PMC7275948 10.1155/2020/6808517 0 0 0 257 Humans|*Congenital Hypothyroidism|Dual Oxidases|*Mutations|Phenotype|NADPH Oxidases|Genotype|Asian Continental Ancestry Group 241 FOXE1 32241916 J. Biol. Chem. 2020 PMC7242714 10.1074/jbc.RA120.012656 0 0 0 257 Rats|Animals|*Thyroglobulin|*Thyroid Epithelial Cells|*Endoplasmic Reticulum Stress|*Cell Survival|Goiter|Endoplasmic Reticulum|Thyroid Gland|Congenital Hypothyroidism|Protein Folding|Tunicamycin|Glycoprotein|*B-Lymphocytes|*Acclimatization 241 FOXE1 32207419 J Pak Med Assoc 2020 10.5455/JPMA.299521 0 0 0 257 *Congenital Hypothyroidism|Thyroid Dysgenesis|NKX2-1 protein, human|Thyroid Nuclear Factor 1|DUOX2|PAX8 Transcription Factor|Homeobox Protein Nkx-2.5|Receptors, Thyrotropin|Gland, Thyroid|High-Throughput Nucleotide Sequencing|Genes, Homeobox|Forkhead Transcription Factors 241 FOXE1 32141546 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202002_20355 0 0 0 257 Humans|*miRNA|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|HCT116 Cells|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Neoplastic Processes|*Colonic Neoplasms|Lymphatic Metastasis|Disease Progression|FOXE1 protein, human|Forkhead Transcription Factors|MIRN802 microRNA, human 241 FOXE1 32102389 J Clin Med 2020 PMC7074206 10.3390/jcm9020606 0 0 0 257 *Pericytes|*Burn|Wound Healing|Skin|Scarring|Dermis|Fibroblasts|*Exudates and Transudates|Mesenchymal Stem Cells|Regenerative Medicine|*Skin Diseases|Fibrosis 241 FOXE1 32081560 Urol. Oncol. 2020 10.1016/j.urolonc.2020.01.007 0 0 0 257 *Urinary Bladder Neoplasms|Twist-Related Protein 1|DNA Methylation|Biomarkers, Tumor|Nuclear Proteins 241 FOXE1 31944555 Orthod Craniofac Res 2020 10.1111/ocr.12366 0 0 0 257 *Cleft Lip|*Cleft Palate|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Gene Frequency|Case-Control Studies 241 FOXE1 31918722 Cell Commun. Signal 2020 PMC6953170 10.1186/s12964-019-0502-8 2 0 0 257 Humans|*Colorectal Cancer|*Cell Proliferation|*Colonic Neoplasms|Hexokinase|MicroRNAs|Gene Expression Regulation, Neoplastic|Glycolysis|Cell Line, Tumor|Signal Transduction|*Transcription Factor|FOXE1 protein, human|Forkhead Transcription Factors 241 FOXE3 32499604 Genet. Med. 2020 10.1038/s41436-020-0854-x 0 0 0 58 Eye Abnormalities|Anterior Eye Segment|Homeodomain Proteins|Pedigree|DNA Mutational Analysis|PAX6 Transcription Factor|Cytochrome P-450 CYP1B1|Mutation|Glaucoma|Forkhead Transcription Factors 110 FOXE3 32436650 Acta Ophthalmol 2020 10.1111/aos.14427 0 0 0 58 Child|Young Adult|Humans|*Anophthalmos|*Microphthalmos|Ocular Prosthesis|Phenotype 110 FOXE3 32224865 Genes (Basel) 2020 PMC7230952 10.3390/genes11040350 0 0 0 58 Florida|Anterior segment mesenchymal dysgenesis|*Eye Abnormalities|CYP1B1 protein, human|Cytochrome P-450 CYP1B1|Anterior Eye Segment|Homeodomain Proteins|Cornea|Pedigree|Iris|Mutation|Forkhead Transcription Factors 110 FOXF1 32600276 BMC Pediatr 2020 PMC7322906 10.1186/s12887-020-02200-y 0 0 0 427 Infant, Newborn|Humans|Alveolar capillary dysplasia|Poland|*Persistent Fetal Circulation Syndrome|*Pulmonary Alveoli|*Genotype-Phenotype Correlation|Lungs|Hypertension, Pulmonary|Pulmonary Veins|Forkhead Transcription Factors|Mutation|Respiratory Insufficiency|Biopsy|FOXF1 protein, human 269 FOXF1 32597710 Am. J. Physiol. Gastrointest. Liver Physiol. 2020 10.1152/ajpgi.00387.2019 0 0 0 427 Humans|Mice|Animals|*Intestinal Mucosa|Intestine, Small|Tissue Engineering|Organoids|*Progenitor Cell|*Duodenum|Cell Differentiation|Epithelial Cells|Cell Proliferation|FOXF1 protein, human|Forkhead Transcription Factors 269 FOXF1 32509446 PeerJ 2020 PMC7245335 10.7717/peerj.9038 0 0 0 427 Humans|*Glioma|Brain Neoplasms|Prognosis|Gene Expression Profiling|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Macrophage|Transcriptome|Computational Biology|*Neovascularization, Pathologic|Algorithms 269 FOXF1 32496870 J. Recept. Signal Transduct. Res. 2020 10.1080/10799893.2020.1772299 0 0 0 427 *Angiotensin II|SMAD3 protein, human|*Smad3 Protein|TGFB1 protein, human|*Transforming Growth Factor beta1|*Fibroblasts|*Signal Transduction|Myofibroblasts|*Heart|Fibrosis|Cell Differentiation|Myocardium|Type I Collagen|FN1 protein, human|Fibronectin|Extracellular Matrix|Cell Proliferation|Myocardial Infarction 269 FOXF1 32413891 Pediatr. Res. 2020 10.1038/s41390-020-0931-5 0 0 0 427 Infant, Newborn|Humans|Alveolar capillary dysplasia|*Persistent Fetal Circulation Syndrome|*Pulmonary Alveoli|*Pulmonary Veins|Lung|Heterozygote|Forkhead Transcription Factors|Mutation|Sequencing, Next-Generation|FOXF1 protein, human 269 FOXF1 32386508 Diagn Pathol 2020 PMC7211333 10.1186/s13000-020-00972-6 0 0 0 427 269 FOXF1 32370197 Int J Mol Sci 2020 PMC7246752 10.3390/ijms21093227 0 0 0 427 269 FOXF1 32319573 Int. J. Oncol. 2020 PMC7115358 10.3892/ijo.2020.5003 0 0 0 427 269 FOXF1 32271448 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202003_20698 1 0 0 427 269 FOXF1 32251605 Cancer Biother. Radiopharm. 2020 10.1089/cbr.2019.3468 0 0 0 427 269 FOXF1 32244228 Aging (Albany NY) 2020 PMC7185122 10.18632/aging.102978 0 0 0 427 269 FOXF1 32240596 Am. J. Respir. Crit. Care Med. 2020 PMC7328311 10.1164/rccm.201906-1232OC 1 0 0 427 269 FOXF1 32169823 Stem Cell Res 2020 10.1016/j.scr.2020.101745 0 0 0 427 Infant, Newborn|Humans|Alveolar capillary dysplasia|*Pulmonary Veins|*Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins|*Heterozygote|*Mutations|Pulmonary Alveoli|Lung|Phenotype|Forkhead Transcription Factors|*Induced Pluripotent Stem Cells|FOXF1 protein, human 269 FOXF1 32036090 J Mol Diagn 2020 PMC7193866 10.1016/j.jmoldx.2019.12.007 0 0 0 427 Humans|Infant, Newborn|Alveolar capillary dysplasia|*Persistent Fetal Circulation Syndrome|Comparative Genomic Hybridization|*Mosaicism|*Pulmonary Alveoli|*Pulmonary Veins|DNA Copy Number Variations|Pedigree|Allele|Forkhead Transcription Factors|*PCR|FOXF1 protein, human 269 FOXF1 31993350 Transl Pediatr 2020 PMC6970114 10.21037/tp.2019.04.01 0 0 0 427 Humans|Mice|Animals|Esophageal atresia with or without tracheoesophageal fistula|*Tracheoesophageal Fistula|*Esophageal Atresia|Esophagus|*Gastrointestinal Diseases|Prevalence|FOXF1 protein, human|Forkhead Transcription Factors 269 FOXF1 31982134 Biochem. 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Commun. 2020 10.1016/j.bbrc.2020.01.062 0 0 0 427 Animals|Mice|Long Non-Coding RNA|SMAD3 protein, human|*Smad3 Protein|MicroRNAs|Cell Proliferation|Fibrosis|Pulmonary Fibrosis 269 FOXF1 31981979 EBioMedicine 2020 PMC6992955 10.1016/j.ebiom.2020.102626 1 0 0 427 Humans|Female|*Osteogenesis|*Wnt Signaling Pathway|Bone Marrow Mesenchymal Stem Cells|Cell Differentiation|Bone Marrow Cells|beta Catenin|*Ovariectomy|*Bone Diseases, Metabolic|*Catenins|Bone|Osteoporosis|Osteocalcin|Cells, Cultured|FOXF1 protein, human|Forkhead Transcription Factors 269 FOXF2 32601340 Sci Rep 2020 PMC7324394 10.1038/s41598-020-67378-8 0 0 0 209 Humans|*Lung Cancer|*Early Detection of Cancer|Tomography, X-Ray Computed|Screening|Lung|Risk Factors|Cohort Studies|FOXF2 protein, human|Forkhead Transcription Factors 118 FOXF2 32582291 Front Genet 2020 PMC7297042 10.3389/fgene.2020.00558 0 0 0 209 Humans|Sheep|Animals|*DNA Copy Number Variations|*Genome|Breeding|Genotype|Oligonucleotide Array Sequence Analysis|Variations, Genomic Structural|Segmental Duplication|Polymorphism, Single Nucleotide|*Body Weight|Chinese 118 FOXF2 32503970 Cell Death Dis 2020 PMC7275069 10.1038/s41419-020-2604-z 0 0 0 209 *Embryonic Development|Forkhead Box Transcription Factors|Signal Pathways|Gene Expression Regulation, Neoplastic|Organogenesis|Tumorigenesis|*Tumor 118 FOXF2 32424142 Cell Death Differ. 2020 10.1038/s41418-020-0555-7 0 0 0 209 Humans|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Forkhead Transcription Factors|Signal Transduction|*Neoplastic Processes|Cell Line, Tumor|Cell Movement|Upregulation|Cell Proliferation|Transforming Growth Factor beta|MicroRNAs|FOXF2 protein, human|Mirn182 microRNA, human 118 FOXF2 32103872 World J. Gastroenterol. 2020 PMC7029353 10.3748/wjg.v26.i6.627 1 0 0 209 *Wnt Signaling Pathway|*Colorectal Cancer|beta Catenin|*Colonic Neoplasms|MicroRNAs|*Catenins|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Proliferation|Cell Movement|Cell Line, Tumor|Cadherins|Down-Regulation|Vimentin|Apoptosis 118 FOXF2 32040930 J. Dent. Res. 2020 PMC7088206 10.1177/0022034520904018 0 0 0 209 Humans|Cleft Palate|Palate|Hedgehog Proteins|Mesoderm|Gene Expression Regulation, Developmental|Morphogenesis|Transcription Factors|Signal Transduction|Cell Proliferation|FOXF2 protein, human|Forkhead Transcription Factors 118 FOXF2 32022446 J. Cell. Mol. Med. 2020 PMC7077542 10.1111/jcmm.14708 1 0 0 209 Humans|Female|Rats|Animals|SMAD6 protein, human|*Smad6 Protein|*Collagen|*Uterine Diseases|*Tissue Adhesions|Fibrosis|Transforming Growth Factor beta1|Endometrium|Collagen Type I|Transfection|Signal Transduction|Up-Regulation|Cells, Cultured|Uterus|Epithelial Cells|FOXF2 protein, human|Forkhead Transcription Factors|Smad6 protein, rat 118 FOXF2 32014885 Biol Open 2020 PMC7075044 10.1242/bio.049478 0 0 0 209 *Mouth Neoplasms|Carcinoma, Squamous Cell|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Epithelial-Mesenchymal Transition|Cell Movement|Carcinoma, Hepatocellular|*Neoplastic Processes|Hepatocellular Cancer 118 FOXF2 31957802 J. Gerontol. A Biol. Sci. Med. Sci. 2020 10.1093/gerona/glaa027 0 0 0 209 Animals|Humans|Aged, 80 and over|Caenorhabditis elegans|Decompression Sickness|*Aging|Embolism, Air|Gene Expression Regulation|*Gene Expression|*B-Lymphocytes|Sirt1|Genetic Loci|*Biochemical Phenomena|FOXF2 protein, human|Forkhead Transcription Factors 118 FOXF2 31933939 Int J Clin Exp Pathol 2020 PMC6947055 0 0 0 209 Humans|Female|*Cell Proliferation|*Endometrial Carcinoma|miRNA|Cell Migration|Downregulation|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Up-Regulation|Forkhead Transcription Factors|RNA Interference|*Neoplastic Processes|FOXF2 protein, human|Mirn182 microRNA, human 118 FOXJ3 32305992 Med. Sci. Monit. 2020 PMC7191964 10.12659/MSM.920623 0 0 0 127 Humans|*RNA, Circular|*Colorectal Carcinoma|RNA, Micro|Cell Proliferation|Cell Migration|Apoptosis|Gene Expression Regulation, Neoplastic|ITGA5 protein, human|*Integrins|Genes, Tumor Suppressor|Cell Line, Tumor|Carcinogenesis|Upregulation|FoxJ3 protein, human|Cell Cycle Proteins|Forkhead Transcription Factors|MIRN107 microRNA, human 21 FOXL1 32196466 IET Syst Biol 2020 10.1049/iet-syb.2019.0074 0 0 0 224 *Risk Factors|Protein Interaction Maps|Gene Ontology|Gene Expression Profiling|Gene Regulatory Networks|Computational Biology|Gene Expression Regulation, Neoplastic|Transcriptome|Protein Interaction Mapping|miRNAs|Biomarkers, Tumor|Transcription Factors|Microarray Analysis|Genes, cdc|Signal Transduction|Cell Cycle Proteins|*Myocardial Diseases 103 FOXL1 32096153 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202002_20176 0 0 0 224 *Nonsmall Cell Lung Cancer|*RNA, Long Noncoding|Lung Neoplasms|*Disease Progression|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Cell Movement|RNA, Small Interfering 103 FOXL1 32093341 Int J Environ Res Public Health 2020 PMC7068514 10.3390/ijerph17041373 0 0 0 224 *Follicular Thyroid Carcinoma|*Thyroid Cancers|Gene Ontology|Gene Regulatory Networks|RNA, Micro|Gene Expression Profiling|Transcriptomes|Gene Expression Regulation, Neoplastic|Computational Biology|Genes, cdc|Microarray Analysis|*Somatostatin-Secreting Cells|*Genetic Profile|Signal Transduction|Genomes|Transcription Factors 103 FOXL1 32041280 Int J Environ Res Public Health 2020 PMC7037290 10.3390/ijerph17031035 0 0 0 224 Humans|*Computational Biology|*Diabetes Mellitus, Type 2|MIRN124 microRNA, human|MicroRNAs|Transcriptome Analysis|Gene Regulatory Networks|Protein Interaction Maps|*Disease Progression|*Biomarkers|Gene Expression Regulation, Neoplastic|Transcription Factor|Transcriptomes|Up-Regulation|Signal Transduction|Genes, Homeobox|CDC14A protein, human|Phosphoric Monoester Hydrolases|FOXL1 protein, human 103 FOXL1 31972308 Gene 2020 10.1016/j.gene.2020.144387 0 0 0 224 Female|Male|Animals|*Forkhead Box Transcription Factors|*Scallop|Gene Expression Profiling|Phylogeny|Ovary|Gonads|Testis|Gametogenesis|Immunity, Innate 103 FOXN2 32046688 BMC Complement Med Ther 2020 PMC7076854 10.1186/s12906-020-2826-8 0 0 0 138 Humans|ginsenoside B|*Ginsenosides|*Apoptosis|*Epithelial Cells|Lens, Crystalline|*Gene Expression|Oxidative Stress|Reactive Oxygen Species|Hydrogen Peroxide|Cells, Cultured|Blotting, Western 28 FOXN4 32443726 Int J Mol Sci 2020 PMC7279403 10.3390/ijms21103600 0 0 0 65 Animals|Humans|Infant, Newborn|*Interneuron|Cell Differentiation|TAL1 protein, human|T-Cell Acute Lymphocytic Leukemia Protein 1|Homeodomain Proteins|Spinal Cord|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|*Zygotes|Eye Proteins|Zebrafish|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Motor Neuron|VSX1 protein, human 54 FOXN4 32071204 Proc. 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Rep. 2020 PMC7103589 10.1042/BSR20193484 1 0 0 147 *Urinary Bladder Neoplasms|*RNAs, Circular|Cell Proliferation|MicroRNAs|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Movement|FOXP4 protein, human|*Forkhead Transcription Factors|*Neoplastic Processes|Cell Line, Tumor|*Bladder|Tumorigenesis 80 FOXP4 32159250 Cell Biol. Int. 2020 10.1002/cbin.11338 0 0 0 147 *Esophageal Squamous Cell Carcinoma|*RNA, Anti-Sense|*Up-Regulation|*Esophageal Neoplasms|Long Non-Coding RNA|*Transcriptional Activation|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Apoptosis|Cell Line, Tumor|Disease Progression|Messenger RNA 80 FOXP4 31999079 Wiley Interdiscip Rev Dev Biol 2020 10.1002/wdev.375 0 0 0 147 Animals|Humans|FOXP4 protein, human|Forkhead Transcription Factors|*Vertebrate|Repressor Proteins|Brain|Gene Expression|Biological Evolution|Neurodevelopmental Disorders 80 FOXP4 31991068 Cancer Med 2020 PMC7064149 10.1002/cam4.2818 1 0 0 147 Humans|*RNA, Long Noncoding|*RNA, Anti-Sense|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|Prognosis|Cell Line, Tumor|Adenocarcinoma|Base Sequence|Survival Analysis 80 FOXP4 31911853 Am J Cancer Res 2020 PMC6943357 0 0 0 147 *Carcinoma, Hepatocellular|*RNA, Micro|*Tumor Suppressor Protein p53|*Liver Neoplasms|*Genes, Tumor Suppressor|FOXP4 protein, human|*Forkhead Transcription Factors|Cell Proliferation|Gene Expression Regulation, Neoplastic|Downregulation|Hep G2 Cells|Cell Line, Tumor|Cell Movement|Apoptosis|Tumorigenesis|Disease Progression 80 FOXQ1 32592372 Asian Pac. 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Cancer 2020 PMC7023763 10.1186/s12943-020-01149-x 2 0 0 388 *Nasopharyngeal Carcinoma|*Docetaxel|*RNA, Circular|*Drug Resistance, Neoplasm|*Upregulation|MicroRNAs|Nasopharyngeal Neoplasms|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|RNA, Small Interfering|Cell Movement|*Transcriptional Activation|Cell Line, Tumor|Carcinoma 139 FOXQ1 32054232 Asian-australas. J. Anim. Sci. 2020 10.5713/ajas.19.0411 0 0 0 388 Pregnancy|Female|Swine|Animals|*Genome-Wide Association Study|*Phenotype|Litter Size|Quantitative Trait Loci|Polymorphism, Single Nucleotide|*Genetic Backgrounds 139 FOXQ1 32027181 DNA Cell Biol. 2020 10.1089/dna.2019.5088 0 0 0 388 Humans|*Prognosis|*Colorectal Cancer|Gene Ontology|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Expression Profiles|Databases, Genetic|Biomarkers, Tumor|Gene Regulatory Networks|Computational Biology|Signal Transduction|*Colonic Neoplasms|Upregulation 139 FOXQ1 31897182 Oncol Lett 2020 PMC6924180 10.3892/ol.2019.11151 0 0 0 388 Humans|*Oxaliplatin|Vascular Endothelial Growth Factor A|*Colorectal Cancer|RNA, Micro|3' Untranslated Region|Gene Expression Regulation, Neoplastic|Cell Proliferation|Forkhead Transcription Factors|Cell Line, Tumor|Cell Movement|mRNA|Viability, Cell|*Colonic Neoplasms|FOXQ1 protein, human 139 FRG2 32591517 Sci Data 2020 PMC7320173 10.1038/s41597-020-0516-5 0 0 0 17 Humans|Mice|Animals|*Gastrointestinal Microbiome|Microbial Community Structure|Host Microbe Interaction|Bacteria|*Biochemical Phenomena|Animal Models|Biological Transport 47 FRG2 32403250 Sensors (Basel) 2020 PMC7248970 10.3390/s20092728 0 0 0 17 Humans|*Remote Sensing Technology|*Big Data|*Cities|*Environmental Pollution|Environmental Monitoring|Geographic Information Systems|Pollutants|Activities, Human 47 FRG2 32312954 Cell Death Dis 2020 PMC7171093 10.1038/s41419-020-2440-1 0 0 0 17 Humans|Mice|Animals|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|TLR4 protein, human|*Toll-Like Receptor 4|*Signal Transduction|Epithelial-Mesenchymal Transition|Melanoma, Cutaneous Malignant|*Melanoma|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Phosphorylation|Skin Neoplasms|Tumor Microenvironment|Tlr4 protein, mouse 47 FRG2 31961482 Small 2020 10.1002/smll.201906048 0 0 0 17 *Refractometry|*Optical Rotation|Nanoparticles, Metallic|Silver|Gold|Alloys 47 FRG2 31937268 BMC Public Health 2020 PMC6961356 10.1186/s12889-019-8140-z 0 0 0 17 Adult|Humans|Aged|Aged, 80 and over|*Cities|Urban Parks|*Physical Activity|Environment Design|Recreation|China|Residence Characteristics|Urban Population|Germany 47 FRMD4A 32210695 Saudi J Biol Sci 2020 PMC6997863 10.1016/j.sjbs.2019.12.028 1 0 0 33 Animals|*Alzheimer Disease|*Risk Factors|Diabetes Mellitus, Type 2|Amyloid beta-Peptides|tau Proteins|Insulin Resistance|Insulin|Signal Transduction|Brain|Phosphorylation|Oxidative Stress|Middle East 26 Frzb 32493207 BMC Genet. 2020 PMC7271470 10.1186/s12863-020-00862-2 0 0 0 374 Animals|*Chickens|*Tibia|*RNA-Seq|Poultry Diseases|*Osteomyelitis|Housing, Animal|Lameness, Animal|Osteochondrosis|*Bacteria|Necrosis|Bacterial Infections|*Whole Exome Sequencing|Femur|Chondrocytes|*Gene Expression 205 Frzb 32448375 Orphanet J Rare Dis 2020 PMC7245871 10.1186/s13023-020-01372-1 0 0 0 374 *Calpain|Limb-girdle muscular dystrophy type 2A|Limb Girdle Muscular Dystrophy|Muscle Proteins|*Muscle Strength|Myotubes|Muscle, Skeletal|*Gait|Signal Transduction|Mutations|Protein Deficiency 205 Frzb 32213546 J. 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Trans. 2020 10.1042/BST20180450 0 0 0 374 Myxococcus xanthus|Chemotaxis|Signal Transduction|Bacterial Proteins|Phenotype|Mutation|Cytoplasm 205 Frzb 32051336 JCI Insight 2020 PMC7098785 10.1172/jci.insight.131384 0 0 0 374 Animals|Mice|*Glucocorticoid|*Receptors, Glucocorticoid|*Wnt Signaling Pathway|Endothelial Cells|*Receptors, Antigen, B-Cell|Dexamethasone|Upregulation|Cells, Cultured|Response Element|Transcriptional Activation 205 Frzb 31923576 Gene 2020 10.1016/j.gene.2020.144338 0 0 0 374 Mice|Animals|*Geese|*Feathers|Hedgehog Proteins|Morphogenesis|*Skin|Transcriptome Analyses|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Organogenesis|Embryonic Development|In Situ Hybridization|Epidermis|SFRP1 protein, human|Membrane Proteins|Wnt Pathway|Chicken 205 FUBP1 32555178 Cell Death Dis 2020 PMC7303217 10.1038/s41419-020-2674-y 0 0 0 327 Humans|Female|Mice|Animals|RNA, Long Noncoding|*Apoptosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|*Endometrial Cancer|MicroRNAs|*Disease Progression|Cell Movement|Downregulation|*Neoplastic Processes|*Endometrium|FUBP1 protein, human|DNA-Binding Proteins|RNA-Binding Proteins 171 FUBP1 32481602 Cells 2020 10.3390/cells9061347 0 0 0 327 *Cell Survival|DNA Helicases|RNA-Binding Proteins|Proto-Oncogene Proteins c-myc|Gene Expression Regulation, Neoplastic|Tumorigenesis|Biomarkers, Tumor|Cell Line, Tumor|Downregulation|*Cell Division 171 FUBP1 32433053 Chin. Med. J. 2020 PMC7249703 10.1097/CM9.0000000000000758 0 0 0 327 *RNA, Long Noncoding|*RNA, Micro|*Up-Regulation|*RNA, Small Nucleolar|FUBP1 protein, human|*RNA-Binding Proteins|*Pancreatic Cancer|Neoplasm Invasiveness|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|*DNA-Binding Proteins|*Transcriptional Activation|Cell Line, Tumor|Apoptosis 171 FUBP1 32339054 Int. J. Biol. Markers 2020 10.1177/1724600820912252 0 0 0 327 *Up-Regulation|*Tongue Neoplasms|*Prognosis|FUBP1 protein, human|*RNA-Binding Proteins|*Transcriptional Activation|*Squamous Cell Carcinoma of Head and Neck|Proto-Oncogene Proteins c-myc|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Cell Proliferation|Head and Neck Neoplasms 171 FUT2 32628772 Alcohol. Clin. Exp. Res. 2020 10.1111/acer.14405 0 0 0 3485 Mice|Animals|*Ethanol|*Intestines|Alcoholic Liver Disease|Dysbiosis|Intestinal Mucosa|galactoside 2-alpha-L-fucosyltransferase|Fucosyltransferases|Microbiota|Feces 385 FUT2 32511533 medRxiv 2020 PMC7273301 10.1101/2020.05.01.20088054 0 0 0 3485 Humans|*SARS-CoV|COVID-19|severe acute respiratory syndrome coronavirus 2|Coronavirus Infections|Pneumonia, Viral|Betacoronavirus|Severe Acute Respiratory Syndrome|Virus Replication 385 FUT2 32487729 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7306792 10.1073/pnas.1917993117 0 0 0 3485 Animals|Humans|*Homozygote|Gene Frequency|Genetic Variation|Phenotypes|Selection, Genetic|Loss of Function Mutation|Polymorphism, Single Nucleotide|Alleles|Hominidae 385 FUT2 32448707 J. Formos. Med. Assoc. 2020 10.1016/j.jfma.2020.04.017 0 0 0 3485 Child|Humans|galactoside 2-alpha-L-fucosyltransferase|Taiwan|*Gastroenteritis|Norovirus Infection|*Fucosyltransferases|Norovirus|Blood Group Antigens|Genotype|Diarrhea|Genetic Predisposition to Disease|Feces 385 FUT2 32429911 Cardiovasc Diabetol 2020 PMC7238526 10.1186/s12933-020-01038-z 0 0 0 3485 Humans|*Diabetic Nephropathies|*Diabetes Mellitus, Type 1|*Cardiovascular Diseases|Albuminuria|Risk Factors|Follow-Up Studies|*ABO Blood-Group System 385 FUT2 32332841 Sci Rep 2020 PMC7181595 10.1038/s41598-020-64025-0 0 0 0 3485 Child|Humans|Infant, Newborn|Infant|Rotavirus B|*Rotavirus|*Genetic Predisposition to Disease|Brazil|Rotavirus Vaccines|Rotavirus Infections|Gastroenteritis|Blood Group Antigens|Genotype|Phenotype 385 FUT2 32289501 Cell Mol Gastroenterol Hepatol 2020 PMC7301201 10.1016/j.jcmgh.2020.03.006 0 0 0 3485 Humans|*Norovirus|Norovirus Infection|Gastroenteritis|Blood Group Antigens|Genotype|Amino Acid Sequence|*Virus Host Interactions 385 FUT2 32248235 Glycobiology 2020 10.1093/glycob/cwaa030 0 0 0 3485 Cattle|Animals|FUT4 protein, human|*Fucosyltransferases|*Fucose|Influenza A Virus, H1N1 Subtype|*Glycans|Glycosylation|Glycoproteins|Mannose|Substrate Specificities|*Electrophoresis|Epitopes 385 FUT2 32203567 Mol Omics 2020 PMC7299767 10.1039/d0mo00009d 0 0 0 3485 Humans|*Carcinoma, Squamous Cell|Tandem Mass Spectrometry|*Mouth Neoplasms|EGFR protein, human|*Epidermal Growth Factor Receptor|*Glycosylation|*Catenins|Cetuximab|Head and Neck Cancer|Fucosyltransferases|Wnt Signaling Pathway|Glycoprotein|Cell Line, Tumor|Protein Processing, Post-Translational|Phosphorylation|Glycans 385 FUT2 32192193 Viruses 2020 PMC7150750 10.3390/v12030324 1 0 0 3485 Child|Humans|*Rotavirus|Rotavirus Infections|Gastroenteritis|*Genetic Polymorphisms|Genotype|Antigens, Blood Group|Fucosyltransferases|Genetic Predisposition to Disease|Phenotype|*Vaccines|Glycosyltransferases|Mutations|Saliva 385 FUT2 32188998 J. 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Dis. 2020 10.1093/infdis/jiaa101 0 0 0 3485 Infant|Humans|Female|*Rotavirus|Bangladesh|*Rotavirus Vaccines|Rotavirus Infections|Antibodies, Viral|Immunoglobulin A|Seroconversion|Vaccines, Attenuated|Disease Susceptibility 385 FUT2 32117425 Front Genet 2020 PMC7025460 10.3389/fgene.2019.01395 0 0 0 3485 Humans|Mice|Animals|*Otitis Media|Middle Ear|Genetic Predisposition|Eustachian Tube|Immunity|Disease Models, Animal 385 FUT2 32110200 Transfus Med Hemother 2020 PMC7036543 10.1159/000499724 0 0 0 3485 Humans|Male|*Phenotype|Fucosyltransferases|Genotype|ABO Blood-Group System|Alleles|Mutation|Sequence Analysis, DNA|Asian Continental Ancestry Group|*Environment|*Antibodies|Austria 385 FUT2 32070726 Clin. Chim. Acta 2020 10.1016/j.cca.2020.02.011 0 0 0 3485 Latin America|Fucosyltransferases|Alleles|Polymorphism, Single Nucleotide|Polymerase Chain Reaction 385 FUT2 31894325 Int. J. Oncol. 2020 PMC6959459 10.3892/ijo.2019.4953 0 0 0 3485 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Glycosylation|Fucosyltransferases|Fucose|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|*Neoplasms, Second Primary|Phosphorylation|Posttranslational Modification|Prognosis|TSTA3 protein, human|Carbohydrate Epimerases|Ketone Oxidoreductases|FUT6 protein, human 385 GABRD 32606685 Int J Nanomedicine 2020 PMC7310985 10.2147/IJN.S254480 0 0 0 33 Animals|*Silica|*Zebrafish|*Nanoparticles|Oxidative Stress|*Neurotoxicity Syndromes|Signal Transduction 105 GABRD 32565954 Oncol Lett 2020 PMC7286117 10.3892/ol.2020.11573 0 0 0 33 Humans|*Prognosis|*Colonic Neoplasms|*Adenocarcinoma|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|MicroRNAs|Gene Expression Profiling|Biomarkers, Tumor|Computational Biology|RNA, Messenger|Kaplan-Meier Estimate|*Aminobutyric Acid|Colon 105 GABRD 32435195 Front Pharmacol 2020 PMC7218123 10.3389/fphar.2020.00594 0 0 0 33 Animals|Mice|*gamma-Aminobutyric Acid|Wakefulness|Receptors, GABA-A|Sleep|Histamine|Neurons|Brain 105 GABRD 32396280 Mol Genet Genomic Med 2020 PMC7336766 10.1002/mgg3.1255 1 0 0 33 Humans|*Prognosis|Neoplasm Recurrence, Local|*Colon Cancer|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|MicroRNAs|DNA Methylation|Gene Regulatory Networks|Kaplan-Meier Estimate 105 GABRD 31912692 J. Integr. Neurosci. 2020 10.31083/j.jin.2019.04.1207 0 0 0 33 Mice|Animals|*Receptors, GABA A|enhanced green fluorescent protein|Green Fluorescent Proteins|*Cell Membrane|Protein Subunits|Cytoplasm|Xenopus laevis|cDNA 105 GABRG1 32233732 J. Neurotrauma 2020 10.1089/neu.2019.6962 1 0 0 26 *Exome|Migraine with Aura|*Head Trauma|Pedigree|Mutations|Calcium Channels|Sodium-Potassium-Exchanging ATPase|Mutation, Missense|*Neurons|Brain Injuries 48 GABRP 32565954 Oncol Lett 2020 PMC7286117 10.3892/ol.2020.11573 0 0 0 19 Humans|*Prognosis|*Colonic Neoplasms|*Adenocarcinoma|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|MicroRNAs|Gene Expression Profiling|Biomarkers, Tumor|Computational Biology|RNA, Messenger|Kaplan-Meier Estimate|*Aminobutyric Acid|Colon 40 GABRP 32541515 Medicine (Baltimore) 2020 PMC7302588 10.1097/MD.0000000000020682 0 0 0 19 Humans|*Nasopharyngeal Carcinoma|*DNA Methylation|*Prognosis|*B-DNA|Protein Interaction Maps|Gene Ontology|Gene Expression Profiling|Nasopharyngeal Neoplasms|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Computational Biology|Epigenesis, Genetic|Biomarkers, Tumor|Software|Microarray Analysis|China|Middle East|North Africa 40 GABRP 32359161 Mol. Hum. Reprod. 2020 PMC7320820 10.1093/molehr/gaaa029 0 0 0 19 Humans|Female|Pregnancy|*Trophoblasts|*Human Embryonic Stem Cells|Placentation|BMP4 protein, human|Bone Morphogenetic Protein 4|Placenta|Cell Differentiation|Embryonic Stem Cells|Blastocysts|Pre-Eclampsia|VTCN1 protein, human|*V-Set Domain-Containing T-Cell Activation Inhibitor 1|Transforming Growth Factor beta|Activin|Signal Transduction|WFDC2 protein, human|WAP Four-Disulfide Core Domain Protein 2|GABRP protein, human 40 GABRP 32216644 J. Comput. Biol. 2020 10.1089/cmb.2019.0367 0 0 0 19 *Computational Biology|*Prognosis|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Protein Interaction Maps|Kaplan-Meier Analysis|Pancreas 40 GALM 32628542 Am. J. Physiol. Renal Physiol. 2020 10.1152/ajprenal.00183.2020 0 0 0 50 *Podocytes|*Upregulation|*Proteoglycan|Mechanotransduction, Cellular|Glycogen Synthase Kinase 3|*Signal Transduction|Kidney Glomerulus|*Stress, Mechanical|*Transcriptional Activation|Dinoprostone|PTGS2|MTOR protein, human|TOR Serine-Threonine Kinases 173 GALM 32568261 J Anim Sci Technol 2020 PMC7288235 10.5187/jast.2020.62.3.293 0 0 0 50 Cattle|Animals|Republic of Korea|*Breeding|*Phenotypes|Genomics|Genotype|Selection, Genetic|Quantitative Trait Loci|Traits, Complex|Polymorphism, Single Nucleotide 173 GALM 32541446 Medicine (Baltimore) 2020 PMC7302618 10.1097/MD.0000000000019905 0 0 0 50 Humans|*RNA, Long Noncoding|*mRNA|*Chondrocytes|*Osteoarthritis|Gene Regulatory Networks|Gene Expression Profiling|Gene Ontology|Transcriptome|*B-Lymphocytes|*Asian Continental Ancestry Group|Cell Cycle 173 GALM 32533421 J. Appl. 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Commun. 2020 10.1016/j.bbrc.2020.05.036 0 0 0 448 Mice|Animals|GDF11 protein, human|*Growth Differentiation Factors|*Bone Morphogenetic Proteins|Wound Healing|Skin|*Disease Models, Animal|Diabetes Mellitus, Experimental|Signal Transduction|Phosphorylation|Skin Diseases|Gdf11 protein, mouse 316 GDF11 32515551 Stem Cells Transl Med 2020 10.1002/sctm.20-0005 0 0 0 448 Mice|Animals|*Mesenchymal Stem Cells|GDF11 protein, human|*Growth Differentiation Factors|*Myocardial Infarction|*Bone Morphogenetic Proteins|Mesenchymal Stem Cell Transplantation|Heart|Myocardium|Neovascularization, Physiologic|Cell Survival|Apoptosis|Gdf11 protein, mouse|YME1L protein, mouse|Metalloendopeptidases 316 GDF11 32489700 Aging Dis 2020 PMC7220280 10.14336/AD.2019.0610 0 0 0 448 Humans|*Pseudoxanthoma Elasticum|*Aging, Premature|Multidrug Resistance-Associated Proteins|*B Cells|Cells, Cultured|Mutations|*Biomarkers 316 GDF11 32404506 Sci Transl Med 2020 10.1126/scitranslmed.aaz5660 0 0 0 448 Humans|Animals|Endothelial Cells|GDF11 protein, human|Bone Morphogenetic Proteins|*Hypertension, Pulmonary|activin A|*Activin|*Signal Transduction|activin receptor type II-A|*Activin Receptors, Type II|Growth Differentiation Factors|*Cell Differentiation|Bone Morphogenetic Protein Receptors, Type II|Pulmonary Artery|Smooth Muscle Cells|Transforming Growth Factor beta|SMAD2 protein, human|Smad2 Protein|Muscle, Smooth, Vascular 316 GDF11 32396235 J. 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Periodontol. 2020 10.1002/JPER.20-0011 0 0 0 448 Humans|Swine|Animals|*Osteogenesis|*Mesenchymal Stem Cells|*Diabetes Mellitus, Type II|*Tooth Socket|*Tooth Extraction|*Periodontal Ligament|GDF11 protein, human|*Growth Differentiation Factors|*Cell Differentiation|*Bone Morphogenetic Proteins|Wound Healing 316 GDF11 32220534 Brain Res. 2020 10.1016/j.brainres.2020.146802 0 0 0 448 Animals|Rats|GDF11 protein, human|*Growth Differentiation Factors|Middle Cerebral Artery Occlusion|*Bone Morphogenetic Proteins|Rats, Sprague-Dawley|*Neuroprotection|Neurogenesis|Cerebral Cortex|Disease Models, Animal|Neovascularization, Pathologic 316 GDF11 32190624 World J Clin Cases 2020 PMC7062616 10.12998/wjcc.v8.i5.874 0 0 0 448 Middle Aged|Aged|Male|Humans|Brachytherapy|Prognosis|Iodine Radioisotopes|Neoplasm Recurrence, Local|Oral Cancer|Tomography, X-Ray Computed 316 GDF11 32165710 Sci Rep 2020 PMC7067781 10.1038/s41598-020-61443-y 0 0 0 448 Humans|Mice|Animals|GDF11 protein, human|*Growth Differentiation Factors|*Body Weight|*Bone Morphogenetic Proteins|Diet, High-Fat|*Homeostasis|Insulin Resistance|Obesity|Weight Gain|B-insulin|Insulin|Muscle, Skeletal|Aging|Proteins|Glucose|Mice, Inbred C57BL|Biotin|Gdf11 protein, mouse 316 GDF11 32104967 Proteomics 2020 10.1002/pmic.201900104 0 0 0 448 Humans|Male|Female|Animals|Mice|MSTN protein, human|*GDF-8|Chromatography, Liquid|Tandem Mass Spectrometry|GDF11 protein, human|*Growth Differentiation Factors|*Bone Morphogenetic Proteins|Aging|Muscle, Skeletal|Amino Acid Sequence|Muscular Diseases|Gdf11 protein, mouse 316 GDF11 32078585 JCI Insight 2020 PMC7213789 10.1172/jci.insight.127018 0 0 0 448 Humans|Male|Aged|Mice|Animals|*Sarcopenia|*Androgen Antagonists|*Prostate Cancers|*Factor 11|Frail Elderly|GDF11 protein, human|Growth Differentiation Factors|Bone Morphogenetic Proteins|Antineoplastic Agents, Hormonal|Muscle, Skeletal|Prostate|Orchiectomy|*Hormone Replacement Therapy|Gdf11 protein, mouse 316 GDF11 32071240 Proc. 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Gerontol. 2020 10.1016/j.exger.2020.110869 0 0 0 448 Humans|Male|Aged|MSTN protein, human|*Myostatin|*Follistatin|*Sarcopenia|GDF11 protein, human|*Growth Differentiation Factors|*Body Composition|*Bone Morphogenetic Proteins|Resistance Training|Muscle Strength|Muscle, Skeletal 316 GIGYF2 32657267 Elife 2020 10.7554/eLife.60038 0 0 0 191 Humans|*Ribosome|Protein Biosynthesis|mRNA|Ubiquitination|Ubiquitin|Carrier Proteins|*Protein Processing, Post-Translational|Ubiquitin-Protein Ligases|HEK293 Cells|*Proteomics|ZNF598 protein, human 64 GIGYF2 32614269 Hum Fertil (Camb) 2020 10.1080/14647273.2020.1786172 0 0 0 191 Humans|Male|*miRNAs|*Computational Biology|*Infertility, Male|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Protein Interaction Maps|Sperm|Gene Expression|Cell Movement 64 GIGYF2 32311426 Biochimie 2020 10.1016/j.biochi.2020.04.010 0 0 0 191 Animals|ZFP36 protein, human|Tristetraprolin|AU Rich Elements|*Transcription Factors|mRNA|TYRP1 protein, human|*Membrane Glycoproteins|Cell Lines|Regulatory Sequences, Nucleic Acid 64 GIMAP4 32523132 Sci Rep 2020 PMC7286899 10.1038/s41598-020-66469-w 0 0 0 68 Humans|Female|*Down Syndrome|*Transcriptome|*GTPases|*Trisomy|Biomarkers, Tumor|Gene Expression Profiling 29 GIMAP4 32045668 Genomics 2020 10.1016/j.ygeno.2020.02.005 0 0 0 68 *Lung Cancer|Gene Regulatory Networks|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Computational Biology|Gene Expression Regulation, Neoplastic 29 GLCCI1 32663566 J Shoulder Elbow Surg 2020 10.1016/j.jse.2020.06.036 0 0 0 103 *Rotator Cuff|Rotator Cuff Injuries|Genetic Predisposition|*Genetics, Population|Polymorphism, Single Nucleotide|Case-Control Studies 47 GLDN 32644941 Aging (Albany NY) 2020 10.18632/aging.103454 0 0 0 88 *Carcinoma, Hepatocellular|*Prognosis|*Gene Regulatory Networks|*Liver Neoplasms|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Protein Interaction Maps|Transcriptome|Kaplan-Meier Estimate|ROC Curve|RNA, Messenger|Liver 30 GLDN 32532872 Appl. Environ. Microbiol. 2020 10.1128/AEM.00799-20 0 0 0 88 30 GLDN 32245758 Appl. Environ. Microbiol. 2020 PMC7237789 10.1128/AEM.00242-20 0 0 0 88 *Cytophaga|Cytophaga hutchinsonii|Cellulase|Cellulose|Bacterial Proteins 30 GLIPR2 32568133 Technol Health Care 2020 10.3233/THC-202138 0 0 0 52 *MicroRNAs|*Computational Biology|*Osteosarcoma|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|mRNA|Gene Expression Profiling|Gene Ontology|Oligonucleotide Array Sequence Analysis|Up-Regulation|Signal Transduction|Cell Line, Tumor|Gene Expression 21 glis1 32579386 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2020 10.1152/ajpregu.00110.2020 0 0 0 33 Humans|*Genome-Wide Association Study|*Polymorphism, Single Nucleotide|*Hand Strength|*Body Composition|Genotype|Phenotype|Genetic Predisposition to Disease|Allele|*Athletes|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 45 glis1 32047936 Carcinogenesis 2020 10.1093/carcin/bgaa010 1 0 0 33 Humans|WNT5A protein, human|*Wnt-5a Protein|*Cell Motility|Transcription Factor|Kruppel-Like Transcription Factors|Gene Expression Regulation, Neoplastic|Zinc Finger|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Cell Hypoxia|siRNA|Hypoxia|GLIS1 protein, human|DNA-Binding Proteins 45 GLRX 32542995 FEBS J. 2020 10.1111/febs.15452 0 0 0 415 GLRX protein, human|Glutaredoxin|Iron-Sulfur Proteins|Mitochondrial Proteins|*Dimerization|Sulfur|Mitochondria|Spectroscopy|Iron 191 GLRX 32378537 Kurume Med J 2020 10.2739/kurumemedj.MS661009 0 0 0 415 Humans|*Antioxidants|Mouth Neoplasms|Carcinoma, Squamous Cell|Leukoplakia, Oral|Fibrosis, Oral Submucous|Lichen Planus, Oral|*Mouth Diseases|*Mitochondria|Mouth Mucosa|Stresses, Oxidative|Glutathione|Reactive Oxygen Species 191 GLRX 32141127 FASEB J. 2020 10.1096/fj.201902575R 0 0 0 415 Mice|Animals|*Adipogenesis|*Protein S|*CCAAT Enhancer Binding Protein|Cell, 3T3-L1|CCAAT-Enhancer-Binding Protein-beta|Adipocytes|Cell Differentiation|GLRX protein, human|Glutaredoxin 1|Ubiquitin Ligase E3|Mice, Knockout|Pias1 protein, mouse|Protein Inhibitors of Activated STAT|Glrx protein, mouse 191 GLRX 32096592 Thorac Cancer 2020 PMC7113066 10.1111/1759-7714.13358 0 0 0 415 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Neoplasm Recurrence, Local|TP53 protein, human|*Tumor Suppressor Protein p53|*Ionizing Radiation|*Redox|Apoptosis|Cell Line, Tumor|*Homeostasis|Intracellular Signaling Peptides and Proteins|Up-Regulation|*Cell Death|TRIAP1 protein, human 191 glutaminolysis 32670270 Front Immunol 2020 PMC7326043 10.3389/fimmu.2020.01013 0 0 0 0 Immunologic Memory|CD8-Positive T-Lymphocytes|Lymphocyte Activation|Cell Differentiation 734 glutaminolysis 32624705 Cancer Cell Int. 2020 PMC7329430 10.1186/s12935-020-01357-x 0 0 0 0 palbociclib|*A549 Cells|Carcinoma, Non-Small-Cell Lung|*Glutamine|Lung Neoplasms|*Pyridines|*Piperazines|CDK4 protein, human|Cyclin-Dependent Kinase 4|Cell Proliferation|Cell Line, Tumor|Protein Kinase Inhibitors|Retinoblastoma Protein|Gene Expression Regulation, Neoplastic|Apoptosis|Xenograft Model Antitumor Assays|Nucleotides 734 glutaminolysis 32602217 2020 10.1002/art.41420 0 0 0 0 CD8-Positive T-Lymphocytes|Arthritis, Rheumatoid|Glycolysis|Cell Proliferation 734 glutaminolysis 32578448 Nutr Cancer 2020 10.1080/01635581.2020.1783329 0 0 0 0 *miRNAs|*Cell Cycle Arrest|*Apoptosis|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Movement|Oncogenes|Oncogenesis|Upregulation|Glycolysis|Liver Neoplasms|Liquorice|Plant Extracts 734 glutaminolysis 32547946 Front Oncol 2020 PMC7269178 10.3389/fonc.2020.00791 0 0 0 0 Oxidative Phosphorylation|Tricarboxylic Acid Cycle|Glycolysis|Oxidation-Reduction|Proto-Oncogene Proteins c-myc|Mitochondria|Lipid Metabolism|Glucose|Cell Proliferation|Cell Line, Tumor|Tumor Microenvironment|Fatty Acids 734 glutaminolysis 32528480 Front Immunol 2020 PMC7257669 10.3389/fimmu.2020.01027 0 0 0 0 Humans|*T-Lymphocytes, Regulatory|*Th17 Cells|*Lupus Erythematosus, Systemic|Interleukin-17|Lymphocyte Activation|Cell Differentiation|Flow Cytometry 734 glutaminolysis 32471029 Cancers (Basel) 2020 PMC7352851 10.3390/cancers12061371 0 0 0 0 Humans|Male|Female|*Osteosarcoma|Bone Neoplasms|Glycolysis|Cell Line, Tumor|Cell Proliferation|*Disease Progression|Cell Movement|Gene Expression Regulation, Neoplastic|Energy Metabolism|Lung Neoplasms|Metabolome|*Nutrient 734 glutaminolysis 32455924 Cancers (Basel) 2020 PMC7280989 10.3390/cancers12051323 0 0 0 0 Humans|*Proteomics|*Melanoma|Proto-Oncogene Proteins B-raf|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Cell Line, Tumor|*Metabolomic 734 glutaminolysis 32450839 BMC Cancer 2020 PMC7333265 10.1186/s12885-020-06885-3 0 0 0 0 Humans|*Glutaminase|*Triple-Negative Breast Cancer|*Pyruvate|CB-839|Benzeneacetamides|Thiadiazoles|Glutamine|Cell Line, Tumor|Xenograft Model Antitumor Assays|Glutamate|Cell Proliferation|Citric Acid Cycle|*Biochemical Phenomena 734 glutaminolysis 32447069 Nucl. Med. Biol. 2020 10.1016/j.nucmedbio.2020.03.006 0 0 0 0 *Glutamine|Fluorine Radioisotopes|Positron-Emission Tomography|Radiopharmaceuticals|Molecular Imaging|Cell Line, Tumor|Tissue Distribution 734 glutaminolysis 32406133 J Dig Dis 2020 10.1111/1751-2980.12882 0 0 0 0 Humans|*Fibrosis|Inflammatory Bowel Diseases|Crohn's Disease|Inflammation|Stenosis|Wound Healing 734 glutaminolysis 32386551 Cell Stem Cell 2020 10.1016/j.stem.2020.04.007 0 0 0 0 *Polyadenylation|*Hematopoietic Stem Cell|Stem Cell Self-Renewal|Cell Differentiation|Cell Proliferation|Hematopoietic Stem Cell Transplantation|Cells, Cultured 734 glutaminolysis 32383454 Int. Immunol. 2020 10.1093/intimm/dxaa019 0 0 0 0 *Amino Acids|Arginase|Arginine|Nitric Oxide Synthase|Glutamine|Polyamines|Biological Transport|Tryptophan|Immune System 734 glutaminolysis 32381854 Gan To Kagaku Ryoho 2020 0 0 0 0 Humans|*Glutamine|*CD8-Positive T-Lymphocytes|Adoptive Transfer|Immunologic Memory|Immunotherapy, Adoptive|Lymphocyte Activation|Lymphocytes, Tumor-Infiltrating|T Cell Receptor|Immunotherapy|Cell Line, Tumor 734 glutaminolysis 32380424 iScience 2020 PMC7205768 10.1016/j.isci.2020.101085 0 0 0 0 Humans|*BCG Vaccine|*Upregulation|Glycolysis|*Transcriptional Activation|Proto-Oncogene Proteins c-myc|*Diabetes Mellitus|MTOR protein, human|TOR Serine-Threonine Kinases|Glucose|*Carbohydrate Metabolism|Transcription Factor|*Vaccination 734 glutaminolysis 32373781 Nat Metab 2020 PMC7199465 10.1038/s42255-019-0084-1 0 0 0 0 Humans|*Citric Acid Cycle|*Glutamine|*Glucose|*HIV-1|*CD4-Positive T-Lymphocytes|Glycolysis|Oxidative Phosphorylation|*HIV Infections|Pentosephosphate Pathway|*Carbon|Pyruvate|Lactate|Mitochondria 734 glutaminolysis 32365457 Cancers (Basel) 2020 PMC7281071 10.3390/cancers12051097 0 0 0 0 Class I Phosphatidylinositol 3-Kinases|Aspirin|Phosphatidylinositol 3-Kinases|Colorectal Neoplasms|Anti-Inflammatory Agents, Non-Steroidal|Mutation|Cell Line, Tumor 734 glutaminolysis 32355746 Ann Transl Med 2020 PMC7186745 10.21037/atm.2020.03.31 0 0 0 0 *Glutamine|*Carcinoma, Signet Ring Cell|*Colorectal Cancer|Prognosis|Colonic Neoplasms|Stomach Neoplasms|Biomarkers, Tumor 734 glutaminolysis 32353588 Pharmacol. 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Genet. 2020 10.1007/s00439-020-02170-2 0 0 0 189 Humans|*Exome|Kartagener Syndrome|Cilia|Phenotype|Mutation|Nitric Oxide|CEP164 protein, human|Microtubule Proteins 46 GOLGA3 32344265 Ecotoxicol. Environ. Saf. 2020 10.1016/j.ecoenv.2020.110619 0 0 0 189 Animals|*Chickens|*Ammonia|*Proteomics|Poultry Diseases|*Apoptosis|*Thymus Plant|Inflammation|*Biochemical Phenomena 46 GPR158 32599826 Genes (Basel) 2020 10.3390/genes11060694 0 0 0 90 Animals|Humans|Genome-Wide Association Study|ADGRG1 protein, human|*G-Protein-Coupled Receptors|GPRC5C protein, human|Signal Transduction|Ligands|Nerve Tissue Proteins|BAI2 protein, human 33 GPR158 32133296 Front Oncol 2020 PMC7040170 10.3389/fonc.2020.00162 0 0 0 90 Humans|Female|*Immunohistochemistry|*Prognosis|*Carcinoma, Ovarian Epithelial|*Adenocarcinoma, Mucinous|Ovarian Neoplasms|Carcinoma, Endometrioid|Adenocarcinoma, Clear Cell|Biomarkers, Tumor|Tissue Array Analysis|Kaplan-Meier Estimate|*Endometrium 33 GPR174 32342657 Mol Genet Genomic Med 2020 PMC7336758 10.1002/mgg3.1249 1 0 0 18 Male|Humans|Female|*Alleles|*Graves Disease|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Receptors, Thyrotropin|Genetic Predisposition to Disease|Gene Frequency|Case-Control Studies|Hashimoto Disease 26 GPR174 32246145 J. Clin. Endocrinol. Metab. 2020 10.1210/clinem/dgaa170 0 0 0 18 *Graves Disease|Hashimoto Thyroiditis|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Alleles|Autoimmune Diseases|*Hypothyroidism|Genotype|CTLA-4 Antigen|*Cohort Studies 26 GPR174 31918274 Biomed. Pharmacother. 2020 10.1016/j.biopha.2019.109701 0 0 0 18 Mice|Animals|*Angiotensin II|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Signal Transduction|*Inflammation|NF-kappa B|Phosphorylation|Oxidative Stress|Hypertension|Cytokines|Hypertensive Retinopathy|*Retinal Diseases|GPR174 protein, mouse|Receptors, G-Protein-Coupled 26 GPR179 32390181 J. Comp. Neurol. 2020 10.1002/cne.24944 0 0 0 5 Retinal Bipolar Cells|Synapses|Retina|Retinal Cone Photoreceptor Cells|Neurogenesis|Signal Transduction 25 GPR26 32599826 Genes (Basel) 2020 10.3390/genes11060694 0 0 0 71 Animals|Humans|Genome-Wide Association Study|ADGRG1 protein, human|*G-Protein-Coupled Receptors|GPRC5C protein, human|Signal Transduction|Ligands|Nerve Tissue Proteins|BAI2 protein, human 20 GPR26 32024457 Neurol. Res. 2020 10.1080/01616412.2020.1723298 0 0 0 71 20 gpr34 32124599 Biochemistry 2020 10.1021/acs.biochem.0c00061 0 0 0 33 Humans|*Ligands|lysophosphatidylserine|*Lysophospholipids|lysophosphatidic acid|Receptors, Lysophospholipid|*G-Protein-Coupled Receptors|*Hydrophobic and Hydrophilic Interactions|Lipid Bilayer|Protein Binding|*Membrane|Cell Membrane|HEK293 Cells 42 GPR64 32203115 Int J Obes (Lond) 2020 10.1038/s41366-020-0570-2 0 0 0 39 Mice|Animals|*Adipocytes|Adipogenesis|3T3-L1 Cells|Adipose Tissue|Lipolysis|*G-Protein-Coupled Receptors|Lipid Metabolism|Cell Differentiation|Obesity 28 GPR64 32180116 Endocrine 2020 10.1007/s12020-020-02263-y 0 0 0 39 *Adenomas|Growth Hormone-Secreting Pituitary Adenoma|Acromegaly|Pituitary Neoplasms|Human Growth Hormone|Growth Hormone|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Biomarkers, Tumor|*Cell Cycle 28 GRID1 32417679 Lung Cancer 2020 10.1016/j.lungcan.2020.03.027 0 0 0 73 Humans|*Exome|Neoplasm Recurrence, Local|*Whole Exome Sequencing|*Sequencing, RNA|*Lung Neoplasms|*Carcinoid Tumor|*Base Sequence|*Carcinoma, Neuroendocrine|Mutation|*Chromosome Aberrations 36 GRID1 32193444 Sci Rep 2020 PMC7081222 10.1038/s41598-020-61883-6 0 0 0 73 Humans|Male|Female|*Alzheimer Disease|*Sequencing, Whole Genome|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Family Relations|ZBTB7C protein, human|Proteins 36 GRID1 32109663 Atherosclerosis 2020 10.1016/j.atherosclerosis.2020.02.005 0 0 0 73 *Prospective Studies|Cholesterol, HDL|Cardiovascular Disease|Genome-Wide Association Study|Genotype|Phenotype|Polymorphism, Single Nucleotide|Lipid Metabolism|Longevity 36 GRID1 32090358 Alcohol. 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Cancer 2020 10.1002/ijc.33166 0 0 0 202 Humans|*Parathyroid Neoplasms|Phosphatidylinositol 3-Kinases|Neoplasm Recurrence, Local|Mutations|*Sequencing, Whole Genome|Tumor Suppressor Proteins|Germline Mutation|DNA Copy Number Variations|Carcinoma|MTOR protein, human|TOR Serine-Threonine Kinases|*Genetic Profile|Genomics|CDC42EP1 protein, human|Adaptor Proteins, Signal Transducing|FAM20A protein, human|Dental Enamel Proteins 70 GRIN3A 31913086 J. Psychopharmacol. (Oxford) 2020 10.1177/0269881119895534 1 0 0 202 *Bipolar Disorder|*MicroRNAs|*Neurite Outgrowth 70 GRIN3B 32289529 J Oral Biosci 2020 10.1016/j.job.2020.03.003 0 0 0 31 Animals|Mice|*Dizocilpine Maleate|*Receptors, N-Methyl-D-Aspartate|N-Methylaspartate|Excitatory Amino Acid Antagonists|*Bone|*Homeostasis 21 GRINA 32657216 Biosci. Biotechnol. Biochem. 2020 10.1080/09168451.2020.1792267 0 0 0 80 Humans|*D-Aspartic Acid|*Aspartate|miRNA|Cell Proliferation|Cell Movement|Downregulation|*Rectal Cancer|Gene Expression Regulation, Neoplastic|*Rectum|Cell Line, Tumor|3' Untranslated Regions|*Glutamate Receptor|Up-Regulation|MIRN296 microRNA, human 74 GRINA 32456296 Diagnostics (Basel) 2020 PMC7277952 10.3390/diagnostics10050336 0 0 0 80 Male|Humans|*Conservative Treatment|*Androgenetic Alopecia|Minoxidil|Hair|Trace Element|Zinc|*Diagnostic Tests, Routine 74 GRINA 32323108 Int J Clin Pharm 2020 10.1007/s11096-020-01035-y 0 0 0 80 Humans|Aged|Aged, 80 and over|*Inappropriate Prescribing|*Cross-Sectional Studies|Lithuania|PIM List|*Hospitalization|Polypharmacy|Patient Discharge|Prevalence|Academic Medical Centers 74 GRINA 32124700 Curr Neuropharmacol 2020 10.2174/1570159X18666200303104235 0 0 0 80 Humans|Depressive Disorder, Major|NMDA Receptors|Glutamate Receptor|*Central Nervous System Diseases|Epilepsy|Neurotransmitters|Alzheimer Disease|Schizophrenia 74 GRINA 31914609 FASEB J. 2020 10.1096/fj.201901626R 1 0 0 80 Humans|*Autophagosomes|*Lysosome|*Membrane Fusion|Autophagy|Anti-Apoptotic Proteins|Microtubule-Associated Proteins|Membrane Proteins|HeLa Cells|Cell Death 74 GSDMB 32496997 Endocr Metab Immune Disord Drug Targets 2020 10.2174/1871530320666200604161656 0 0 0 64 Adult|Humans|Child|*Allergic Rhinitis|Genetic Predisposition to Disease|Genetic Association Studies|Gene Frequency|Polymorphism, Single Nucleotide|Asthma|Genotype|Linkage Disequilibrium|Alleles|Case-Control Studies|Neoplasm Proteins|GSDMA protein, human 108 GSDMB 32491958 Acta Otolaryngol. 2020 10.1080/00016489.2020.1767804 0 0 0 64 108 GSDMB 32444308 Allergol Int 2020 10.1016/j.alit.2020.04.009 0 0 0 64 Humans|Adult|Child|*Orosomucoid|*Risk Factors|Asthma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Hypersensitivity, Immediate|Immunoglobulin E|Allergens|Genotype|Phenotype|Membrane Proteins|Case-Control Studies|ORMDL3 protein, human|GSDMB protein, human|Neoplasm Proteins 108 GSDMB 32431546 Cancer Manag Res 2020 PMC7201009 10.2147/CMAR.S246948 0 0 0 64 *Pyroptosis|*Cancers|Neoplasm Proteins|Programmed Cell Death|Cell Death 108 GSDMB 32380068 Lancet Respir Med 2020 PMC7335429 10.1016/S2213-2600(20)30011-4 0 0 0 64 Child|Humans|*Quantitative Trait Loci|*African Americans|*Asthma|*Chromosome Mapping|Linkage Disequilibrium|Genetic Association Studies|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|*Gene Expression|Case-Control Studies|Neoplasm Proteins 108 GSDMB 32299851 Science 2020 10.1126/science.aaz7548 1 0 0 64 GZMA protein, human|GZMB protein, human|*Granzymes|*Pyroptosis|*Cleavers|Perforin|Cytotoxic T-Lymphocytes|Natural Killer Cells|Pore Forming Cytotoxic Proteins|Apoptosis|Membrane Glycoproteins 108 GSDMB 32294153 Acta Biochim. 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Cancer Res. 2020 10.1158/1078-0432.CCR-19-2803 0 0 0 426 Humans|Pancreatic Carcinoma|*Pancreatic Neoplasms|Carcinoma, Pancreatic Ductal|*Chemokines|CTLA-4 Antigen|Adenocarcinoma|CD8-Positive T-Lymphocytes|*Phenotype 379 GZMK 32655547 Front Immunol 2020 PMC7325996 10.3389/fimmu.2020.01054 0 0 0 54 Animals|GZMM protein, human|GZMB protein, human|*Granzymes|*Sepsis|T-Lymphocytes, Cytotoxic|Specificity 71 GZMK 32606797 Onco Targets Ther 2020 PMC7319516 10.2147/OTT.S248958 0 0 0 54 Humans|*Squamous Cell Carcinoma of Head and Neck|*Prognosis|*Receptors, CXCR5|B7-H1 Antigen|Head and Neck Neoplasms|CD8-Positive T-Lymphocytes|CXCR5 protein, human 71 GZMK 32353685 Int. 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Syndr. 2020 10.1097/QAI.0000000000002437 0 0 0 0 *HIV-1|TLR9 protein, human|*Toll-Like Receptor 9|*HIV Infections|Anti-Retroviral Agents|CD4 Lymphocyte Count|Viral Load|Antiretroviral Therapy, Highly Active|CD4-Positive T-Lymphocytes|*HIV Seropositivity|SNPs 13955 HLA.A 32657047 HLA 2020 10.1111/tan.13995 0 0 0 0 Humans|*Alleles|HLA-A29 antigen|HLA-A Antigens|HLA-B|HLA-C Antigens|Exons|Codon|Histocompatibility Testing|High-Throughput Nucleotide Sequencing|Sequence Analysis, DNA|Asian Continental Ancestry Group|Mutation 13955 HLA.A 32656962 HLA 2020 10.1111/tan.13997 0 0 0 0 *Alleles|HLA-DQ beta-Chains|HLA-DRB1 Chains|India|Gene Frequency|HLA-B|HLA-DQ Antigens|Haplotypes|Histocompatibility Antigens Class I|Genes, MHC Class I 13955 HLA.A 32654962 Hum. Immunol. 2020 10.1016/j.humimm.2020.06.010 0 0 0 0 13955 HLA.A 32651014 Hum. Immunol. 2020 10.1016/j.humimm.2020.06.008 0 0 0 0 *Immunogenetics|Mexico|*Genetics, Population|HLA DRB1|Haplotypes|HLA-DQ beta-Chains|Gene Frequency|Alleles|Linkage Disequilibrium|HLA-DQ Antigens|Histocompatibility Antigens Class I|Genotype 13955 HLA.A 32639066 HLA 2020 10.1111/tan.13992 0 0 0 0 Humans|*Alleles|HLA-C Antigens|Codon|Exons|Histocompatibility Testing|*Asian Continental Ancestry Group|Base Sequence|Sequence Alignment|Amino Acid Substitution|Tissue Donors|Sequence Analysis, DNA|Polymorphism, Single Nucleotide|Genotype|Polymerase Chain Reaction|Hematopoietic Stem Cell Transplantation|Gene Expression|HLA-A Antigens 13955 HLA.A 32635614 J Clin Med 2020 10.3390/jcm9072118 0 0 0 0 Humans|*Kidney Transplantation|*Living Donors|Renal Dialysis|Graft Survival|Tissue and Organ Procurement|Graft Rejection|Immunosuppression|Cadaver|Registries|Time Factors 13955 HLA.A 32634478 Transpl. Immunol. 2020 10.1016/j.trim.2020.101317 0 0 0 0 Humans|*Kidney Transplantation|*Living Donors|*Kidney|Histocompatibility Testing|Histocompatibility|Graft Rejection|Donor Selection|*HLA-B|Tissue and Organ Procurement|Algorithms 13955 HLA.A 32623908 Cell Transplant 2020 10.1177/0963689720926151 0 0 0 0 Humans|*Blood Banks|*Fetal Blood|*Induced Pluripotent Stem Cells|HLA-A Antigens|HLA-B Antigens|Histocompatibility Testing|Haplotypes|HLA-DRB1 Chains|Cord Blood Stem Cell Transplantation|Alleles|Gene Frequency|Histocompatibility Antigens Class I|*Cryopreservation|Homozygote|Donors 13955 HLA.A 32623831 Int. J. Immunogenet. 2020 10.1111/iji.12505 0 0 0 0 Humans|COVID-19|severe acute respiratory syndrome coronavirus 2|Pandemic|HLA-DQB1 antigen|HLA-DQ beta-Chains|HLA DRB1|HLA-B|HLA-C|HLA-DQ Antigens|*Severe Acute Respiratory Syndrome|Gene Frequency|Alleles|Histocompatibility Antigens Class I|Haplotypes|SARS-CoV|Genetic Predisposition to Disease|Donor|Cohort Studies 13955 HLA.A 32623050 Transpl. Immunol. 2020 10.1016/j.trim.2020.101318 0 0 0 0 Humans|*Donors|*Kidney Transplantation|Histocompatibility|Graft Survival|Histocompatibility Testing|End Stage Renal Disease|Transplantation, Homologous|*Polymorphism, Genetic|*Kidney|*Transplants|HLA DRB1|Cadaver|Croatia 13955 HLA.A 32621664 HLA 2020 10.1111/tan.13989 0 0 0 0 Humans|*Alleles|HLA-C Antigens|Exon|*Genomics|Base Sequence|Sequence Analysis, DNA|Cloning, Molecular|Asian Continental Ancestry Group|HLA-A Antigens 13955 HLA.A 32619904 Curr. Opin. Immunol. 2020 10.1016/j.coi.2020.05.008 0 0 0 0 Humans|*HLA-B Antigens|HLA-A Antigens|Histocompatibility Antigens Class I|Adaptive Immunity|Antigen Presentation|*Polymorphism, Genetic|Antigens|Peptides|Histocompatibility 13955 HLA.A 32616301 Hum. Immunol. 2020 10.1016/j.humimm.2020.06.007 0 0 0 0 Humans|*HLA-B|Frequencies, Allele|HLA Typing|Genotype|HLA-DRB1 Chains|HLA-DQ beta-Chains|Haplotypes|India|Alleles|*Caste|Software|HLA-A Antigens 13955 HLA.A 32610710 Cells 2020 10.3390/cells9071581 0 0 0 0 Animals|*CD4-Positive T-Lymphocytes|T Cell Receptor|*CD4 Antigens|CD8-Positive T-Lymphocytes|Immunotherapy, Adoptive|*Animals, Genetically Modified|Antigens, Neoplasm|Transduction, Genetic 13955 HLA.A 32601360 Sci Rep 2020 PMC7324363 10.1038/s41598-020-67610-5 0 0 0 0 Humans|*Stevens-Johnson Syndrome|HLA-B|HLA-C|Genotypes|*Eye|Genetic Predisposition to Disease|Odds Ratios|Case-Control Studies 13955 HLA.A 32594623 HLA 2020 10.1111/tan.13983 0 0 0 0 Humans|*Alleles|HLA-B Antigens|Histocompatibility Testing|HLA-A Antigens 13955 HLA.A 32590431 AIDS 2020 10.1097/QAD.0000000000002559 0 0 0 0 Humans|*HIV-1|*Alleles|nef Gene Products, Human Immunodeficiency Virus|Viral Load|HIV Infections|HLA-C Antigens|Immune Evasion|HIV Seropositivity|Genotype|Host-Pathogen Interactions|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 13955 HLA.A 32589879 Braz J Infect Dis 2020 10.1016/j.bjid.2020.05.009 0 0 0 0 Humans|*Alleles|Cross-Sectional Studies|*Leprosy|Allele Frequency|HLA-A Antigens|HLA-B Antigens|HLA-DQ beta-Chains|HLA-DQ alpha-Chains|Mycobacterium leprae|HLA-C Antigens|HLA-DRB1 Chains|HLA-DQ Antigens|Histocompatibility Antigens Class I|Haplotypes|Histocompatibility Testing|Test, Serological|Brazil 13955 HLA.A 32571843 J. Immunol. 2020 10.4049/jimmunol.1901173 0 0 0 0 Humans|*T Cells|*Cysteine|Epitopes|Antigen Presentation|Amino Acid Sequence|Peptide Fragments|*Tumor 13955 HLA.B 32658127 J. Acquir. Immune Defic. Syndr. 2020 10.1097/QAI.0000000000002437 0 0 0 0 *HIV-1|TLR9 protein, human|*Toll-Like Receptor 9|*HIV Infections|Anti-Retroviral Agents|CD4 Lymphocyte Count|Viral Load|Antiretroviral Therapy, Highly Active|CD4-Positive T-Lymphocytes|*HIV Seropositivity|SNPs 11939 HLA.B 32656962 HLA 2020 10.1111/tan.13997 0 0 0 0 *Alleles|HLA-DQ beta-Chains|HLA-DRB1 Chains|India|Gene Frequency|HLA-B|HLA-DQ Antigens|Haplotypes|Histocompatibility Antigens Class I|Genes, MHC Class I 11939 HLA.B 32654384 HLA 2020 10.1111/tan.13994 0 0 0 0 Humans|*HLA-B|Allele|*Genes, MHC Class I|European Continental Ancestry Group|Recombination, Genetic 11939 HLA.B 32641744 Mod. Pathol. 2020 10.1038/s41379-020-0614-0 0 0 0 0 Female|*Adenocarcinoma, Mucinous|*Cervix Uteri|TP53 protein, human|Tumor Suppressor Protein p53|Mutation|Sequencing, Next-Generation|SMAD4 protein, human|Smad4 Protein|Adenocarcinoma|Pancreatic Neoplasms|Biomarkers, Tumor|KMT2D protein, human|Neoplasm Proteins|Mutation Rate|STK11 protein, human|Protein-Serine-Threonine Kinases 11939 HLA.B 32639997 PLoS Negl Trop Dis 2020 10.1371/journal.pntd.0008436 0 0 0 0 Humans|Child|Animals|Mice|*Nodding Syndrome|*Immunogenetics|HLA-DQ beta-Chains|HLA-DRB1 Chains|Haplotype|*Protein Binding|Alleles|Onchocerca volvulus|Genetic Predisposition to Disease|Antibodies|*Protein Transport|South Sudan 11939 HLA.B 32636246 mBio 2020 PMC7343989 10.1128/mBio.00972-20 0 0 0 0 11939 HLA.B 32624231 Transplant. Proc. 2020 10.1016/j.transproceed.2020.02.135 0 0 0 0 11939 HLA.B 32623908 Cell Transplant 2020 10.1177/0963689720926151 0 0 0 0 11939 HLA.B 32623831 Int. J. Immunogenet. 2020 10.1111/iji.12505 0 0 0 0 11939 HLA.B 32623050 Transpl. Immunol. 2020 10.1016/j.trim.2020.101318 0 0 0 0 11939 HLA.B 32619904 Curr. Opin. Immunol. 2020 10.1016/j.coi.2020.05.008 0 0 0 0 11939 HLA.B 32601360 Sci Rep 2020 PMC7324363 10.1038/s41598-020-67610-5 0 0 0 0 11939 HLA.B 32594661 HLA 2020 10.1111/tan.13984 0 0 0 0 11939 HLA.B 32590431 AIDS 2020 10.1097/QAD.0000000000002559 0 0 0 0 11939 HLA.B 32589879 Braz J Infect Dis 2020 10.1016/j.bjid.2020.05.009 0 0 0 0 11939 HLA.B 32581801 Front Pharmacol 2020 PMC7291871 10.3389/fphar.2020.00842 0 0 0 0 11939 HLA.B 32567246 Immun Inflamm Dis 2020 10.1002/iid3.325 0 0 0 0 11939 HLA.B 32563742 Epilepsy Res. 2020 10.1016/j.eplepsyres.2020.106391 0 0 0 0 11939 HLA.B 32561995 Immunogenetics 2020 10.1007/s00251-020-01172-8 0 0 0 0 11939 HLA.B 32549766 Int. J. Biol. Sci. 2020 PMC7294944 10.7150/ijbs.42080 0 0 0 0 11939 HMCN1 32583281 Mol. Biol. 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Res. 2020 PMC7249385 10.1186/s12917-020-02373-9 0 0 0 37 Pregnancy|Female|Humans|Swine|Male|Animals|*Testis|*Sperm Motility|*Transcriptome Profiling|Sperm|Sequencing, RNA|Litter Size|Breeding|Phenotypes|Base Sequence 47 HMCN1 32414224 Panminerva Med 2020 10.23736/S0031-0808.20.03911-7 0 0 0 37 Humans|Female|*Uterine Cervical Neoplasms|Gene Expression Regulation, Neoplastic|Prognosis|Neoplasm Proteins|Homeodomain Proteins|Cell Proliferation|Cell Movement|Lymphatic Metastasis|Apoptosis|HOXD9 protein, human|HMCN1 protein, human|Immunoglobulins 47 HMCN1 32128068 Comput Struct Biotechnol J 2020 PMC7044470 10.1016/j.csbj.2020.01.011 0 0 0 37 Humans|*Pulmonary Atresia|*High-Throughput Nucleotide Sequencing|*Congenital Heart Defect|Heart Septal Defects, Ventricular|Artery, Pulmonary|Genetic Testing 47 HMCN1 32035013 Dev. Dyn. 2020 10.1002/dvdy.159 0 0 0 37 Mice|Animals|*Extracellular Matrix|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Extracellular Matrix Proteins|Membranes, Basement|Calcium-Binding Proteins|Cell Adhesion|*Mammals|Membrane Proteins 47 HMX1 32649979 Gene 2020 10.1016/j.gene.2020.144945 0 0 0 76 Humans|Mice|Animals|*Genes, Homeobox|*Congenital Microtia|*Mutations|Homeodomain Proteins|Ear, Outer|Transcription Factor|Hearing Impairment|Pedigree|Phenotype|Sequencing, Next-Generation|Regulatory Sequences, Nucleic Acid|*Chinese|HOXA2 protein, human 47 HMX1 32552830 J Transl Med 2020 PMC7302384 10.1186/s12967-020-02409-6 0 0 0 76 Animals|Humans|*Genes, Homeobox|*Congenital Microtia|DNA Copy Number Variations|*Regulatory Sequences, Nucleic Acid|Homeodomain Proteins|*Ear Auricle|Pedigree|Phenotype|Outer Ears|Eye Abnormalities|Mutations 47 HMX1 32481741 Genes (Basel) 2020 PMC7349607 10.3390/genes11060597 0 0 0 76 Sheep|Animals|Sheep, Domestic|Microtia|Genotype|Breeding|Polymorphism, Single Nucleotide|Phenotype|Base Sequence|DNA Sequencing 47 HMX2 32660426 BMC Genomics 2020 10.1186/s12864-020-06894-3 0 0 0 20 Animals|*Transcriptome|*Pinctada|Molecular Sequence Annotation|High-Throughput Nucleotide Sequencing|Gene Expression Profiling|Alternative Splicing|RNA, Long Noncoding 40 HMX2 32547637 Therap Adv Gastroenterol 2020 PMC7273615 10.1177/1756284820905482 0 0 0 20 Humans|*African Americans|*DNA Methylation|CpG Islands|Colorectal Cancer|Promoter Regions, Genetic|Adenoma|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Complement Factor B|Colonic Neoplasms|Gene Expression Profiling 40 HMX2 31960221 Mar. 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Med. 2020 10.1111/jcmm.15010 1 0 0 117 *Carcinoma, Hepatocellular|*Liver Neoplasms|MIRN338 microRNA, human|MicroRNAs|*Up-Regulation|Cell Proliferation|*Disease Progression|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Downregulation|Cell Line, Tumor|Cell Movement|*Transcriptional Activation|Apoptosis|circRNA 129 HN1 31974608 Mol Med Rep 2020 PMC6947897 10.3892/mmr.2019.10862 0 0 0 117 Child|Humans|*Adenosine Deaminase|*Growth Factors|Mutations|Phenotype|Systemic Vasculitis 129 HOOK3 32341549 Nat. 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Exp. Clin. Cancer Res. 2020 PMC7353690 10.1186/s13046-020-01610-1 0 0 0 1465 *RNA, Long Noncoding|*5 Fluorouracil|*Methylation|*Esophageal Cancer|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Proliferation|Cell Movement|Methylenetetrahydrofolate reductase deficiency|*Methylenetetrahydrofolate Reductase (NADPH2)|*Homocystinuria|*Muscle Spasticity|*Psychotic Disorders 889 HOTAIR 32650779 Cell Commun. Signal 2020 PMC7353702 10.1186/s12964-020-00602-0 0 0 0 1465 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|MET protein, human|*Proto-Oncogene Proteins c-met|*Down-Regulation|*Liver Neoplasms|Epithelial-Mesenchymal Transition|*Signal Transduction|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Vimentin|Cell Line, Tumor|Apoptosis|Disease Progression|Phenotypes 889 HOTAIR 32650720 BMC Mol Cell Biol 2020 PMC7350747 10.1186/s12860-020-00299-6 0 0 0 1465 *RNA, Long Noncoding|*Wnt Signaling Pathway|*Osteoarthritis|*Cartilage|beta Catenin|Chondrocytes|RNA Interference|Promoter Regions, Genetic|Apoptosis|Disease Progression 889 HOTAIR 32602030 J. Mol. Neurosci. 2020 10.1007/s12031-020-01623-7 0 0 0 1465 Mice|Animals|*RNA, Long Noncoding|*Myeloid Differentiation Factor 88|*Microglia|*Ubiquitination|shRNA|Cell Line, Tumor|*Traumatic Brain Injury|Transfection|*Adaptor Proteins, Signal Transducing|Myd88 protein, mouse 889 HOTAIR 32601922 Mol. Biol. 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Cancer 2020 10.1002/ijc.33106 0 0 0 56 Rats|Animals|*Oxaliplatin|*Pain, Neuropathic|Horn, Dorsal|Mechanical Allodynia|*Promoter Regions, Genetic|*SOXE Transcription Factors|Upregulation|*Genes, Homeobox|Methylation|siRNA|Demethylation|Sox10 protein, rat|TET1 protein, rat|Dioxygenases 36 HOXA6 32366326 Acta Neuropathol Commun 2020 PMC7197183 10.1186/s40478-020-00940-7 1 0 0 56 Humans|*Transcription Factor|*Neurofibroma|Neurofibromatosis Type I|Plexiform Neurofibromas|*Gene Expression Regulation|Genes, Homeobox|Cell Transformation, Neoplastic|mRNA|DNA Methylation|Orbit 36 HOXB13 32661255 Signal Transduct Target Ther 2020 10.1038/s41392-019-0086-1 0 0 0 285 Humans|HOXB13 protein, human|*Homeodomain Proteins|*Colon|Colon Cancer|Prognosis|*Genes, Homeobox|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|Biomarkers, Tumor 273 HOXB13 32660704 Curr Probl Cancer 2020 10.1016/j.currproblcancer.2020.100616 0 0 0 285 Humans|Male|*Prostate Cancer|Early Detection of Cancer|Prostate-Specific Antigen|Prostate|*Genetic Markers|Biomarkers, Tumor|HOXB13 protein, human|Homeodomain Proteins|Germ-Line Mutation|Biopsies|Genetic Predisposition to Disease 273 HOXB13 32630240 J Clin Med 2020 10.3390/jcm9072066 0 0 0 285 Humans|Male|*Neoplastic Cells, Circulating|*Prostatic Neoplasms, Castration-Resistant|Receptors, Androgen|*Gene Expression|Biomarkers, Tumor|*Cell Count 273 HOXB13 32553107 Elife 2020 10.7554/eLife.53600 0 0 0 285 Male|Humans|Mice|Animals|*Proteoglycans|HOXB13 protein, human|*Homeodomain Proteins|*Prostate Cancer|Myeloid Ecotropic Viral Integration Site 1 Protein|Transcription Factors|Prostate|*Neoplastic Processes|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction 273 HOXB13 32546843 Sci Rep 2020 PMC7297796 10.1038/s41598-020-65665-y 0 0 0 285 Humans|Male|Breast Cancer 3|*Breast Neoplasms|HOXB13 protein, human|Homeodomain Proteins|Germ-Line Mutation|Prostatic Neoplasms|Genetic Predisposition to Disease|Mutations|Case-Control Studies|Genotype|Risk Factors|Genes, Homeobox|Allele|Germ Cells|Netherlands 273 HOXB13 32540218 Eur Urol Oncol 2020 10.1016/j.euo.2020.05.001 0 0 0 285 Humans|Male|*Prostate|*Prostatectomy|*Prostate Cancer|*Disease Progression|*Seminal Vesicles|Homeodomain Proteins|Mutations|*Diploidy|HOXB13 protein, human 273 HOXB13 32516092 J. 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Divers. 2020 10.1007/s11030-020-10116-z 0 0 0 257 Humans|*Sirtuin 2|*Parkinson Disease|Molecular Docking Simulation|Sirtuin 1|Acetylation|Lysine|Tubulin|Tumor Suppressor Protein p53|Peptides|SIRT2 protein, human 202 Hrk 32390192 FEBS Lett. 2020 10.1002/1873-3468.13807 0 0 0 257 *Sheeppox virus|*bcl-2-Associated X Protein|BCL2 protein, human|Proteins, BCL2|Bax protein (53-86)|*Proto-Oncogene Proteins|*Apoptosis|Apoptosis Regulatory Proteins|Bcl-2-Like Protein 11|*Peptide Fragments|Protein Conformation|Viral Proteins|Protein Binding|Crystallography, X-Ray|Amino Acid Sequence 202 Hrk 32148779 F1000Res 2020 PMC7047912 10.12688/f1000research.21571.1 0 0 0 257 Mice|Animals|bcl-2 Homologous Antagonist-Killer Protein|bcl-2-Associated X Protein|BH3 Interacting Domain Death Agonist Protein|Proto-Oncogene Proteins c-bcl-2|Apoptosis Regulatory Proteins|Apoptosis|bcl-X Protein|Bcl-2-Like Protein 11|Proto-Oncogene Proteins|Membrane Proteins|Mitochondria|Cytochromes c|Tumor Suppressor Proteins|Mammalian Embryos|Cells, Cultured 202 Hrk 32028452 J Neuroophthalmol 2020 10.1097/WNO.0000000000000900 0 0 0 257 Humans|Male|Middle Aged|Lymphoma, Large B-Cell, Diffuse|Vascular Neoplasms|Magnetic Resonance Imaging|Biopsy|Brain|Fluorescein Angiography|Diffusion Magnetic Resonance Imaging|Choroid|Visual Field Tests|Tomography, X-Ray Computed|Coherence Tomography, Optical|Stroke 202 Hrk 31974044 Drug Metab. 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Int. 2020 10.1016/j.forsciint.2020.110267 0 0 0 13 Humans|Male|Female|Child, Preschool|Infant|Child|Adolescent|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|*DNA Methylation|*B-DNA|CpG Islands|Forensic Genetics|LIM-Homeodomain Proteins|Aging|Genetic Markers|Acetyltransferases|Muscle Proteins|Transcription Factors|Linear Models|Saliva|Fatty Acid Elongases|*Protein Processing, Post-Translational|TRIM59 protein, human|Membrane Proteins|Metalloproteins 86 KLF14 32211384 Front Bioeng Biotechnol 2020 PMC7075810 10.3389/fbioe.2020.00080 0 0 0 13 Humans|CpG Islands|DNA Methylation|Forensic Genetics|Sequence Analysis, DNA|Aging|Algorithm|Biomarkers|Saliva 86 KLF14 32087494 Forensic Sci Int Genet 2020 10.1016/j.fsigen.2020.102261 0 0 0 13 Male|CpG Islands|*Epigenetic|DNA Methylation|Forensic Genetics|Genetic Markers|Acetyltransferases|*Bone|DNA|Saliva|Epigenesis, Genetic 86 KLF14 32006895 Forensic Sci Int Genet 2020 10.1016/j.fsigen.2020.102251 0 0 0 13 Humans|Child, Preschool|Child|Adolescent|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|CpG Islands|DNA Methylation|Forensic Genetics|cytidylyl-3'-5'-guanosine|*Dinucleoside Phosphates|Sequence Analysis, DNA|Aging|Genetic Markers|DNA|*Asian Continental Ancestry Group|Linear Models 86 KLF14 31925990 Biofactors 2020 10.1002/biof.1612 0 0 0 13 Sp Transcription Factors|Signal Transduction|Kruppel-Like Transcription Factors|Insulin Resistance|Cell Differentiation 86 KLF16 32318089 Front Genet 2020 PMC7154154 10.3389/fgene.2020.00230 0 0 0 93 Humans|*Trophoblasts|BMP4 protein, human|*Bone Morphogenetic Protein 4|*Pluripotent Stem Cells|Embryonic Stem Cells|Cell Differentiation|Cell Lines|*Genome, Human|Gene Expression Regulation, Developmental|Gene Expression Profiling|Transcriptomes|Genomics 26 KLF16 32103997 Onco Targets Ther 2020 PMC7025737 10.2147/OTT.S233495 0 0 0 93 Humans|Male|*Prostate Cancer|Kruppel-Like Transcription Factors|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis 26 KLF16 32096311 FEBS J. 2020 10.1111/febs.15259 0 0 0 93 *Arachidonate 5-Lipoxygenase|*Binding Proteins|*Proteomics|DNA-Binding Proteins|Cell Line, Tumor|*Promoter Regions, Genetic|Sp1 Transcription Factor|Gene Expression Regulation|DNA|G Quadruplexes|Asthma 26 KLF8 32411796 J Immunol Res 2020 PMC7204180 10.1155/2020/4036047 0 0 0 370 Humans|*Signal Transduction|Adenocarcinoma of Lung|MicroRNAs|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Cell Movement|Epithelial-Mesenchymal Transition|*Neoplastic Processes|Cell Line, Tumor|3' Untranslated Regions|Cell Proliferation|Tumor Microenvironment|KLF8 protein, human|Repressor Proteins|MIRN24 microRNA, human 102 KLF8 32224525 Cancer Biomark 2020 10.3233/CBM-191121 0 0 0 370 *Pituitary Neoplasms|Adenoma|Vision Disorders 102 KLF8 32122144 Neoplasma 2020 10.4149/neo_2020_190711N624 0 0 0 370 *Factor 8|*Osteosarcoma|*Cancer Stem Cell|*Signal Transduction|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Downregulation|Up-Regulation|Repressor Proteins|*Phenotypes|Tumorigenesis 102 KLF8 32105190 Anim. Biotechnol. 2020 10.1080/10495398.2020.1732397 0 0 0 370 Mice|Animals|*Goat|*Cell Differentiation|Adipogenesis|Adipocytes|3T3-L1 Cells|PPAR gamma|Lipid Metabolism 102 KLF8 31974291 Mol. Cancer Res. 2020 PMC7127962 10.1158/1541-7786.MCR-19-0732 0 0 0 370 O-GlcNAc transferase|*N-Acetylglucosaminyltransferases|UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase|Acetylglucosamine|Cancer Stem Cells|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Transformation, Neoplastic|Apoptosis|Tumor Microenvironment 102 KLK10 32592124 Head Neck Pathol 2020 10.1007/s12105-020-01196-2 0 0 0 169 Humans|*Tissue Kallikreins|KLK15 protein, human|*Kallikrein B'|*Adenocarcinoma|Immunohistochemistry|Salivary Gland Neoplasms|*Polymerase Chain Reaction|mRNA|Gland, Salivary|Complementary DNA|KLK10 protein, human|KLK12 protein, human 148 KLK10 32402941 Mol Ther Nucleic Acids 2020 PMC7218230 10.1016/j.omtn.2020.04.009 0 0 0 169 Humans|Female|*Uterine Cervical Neoplasms|*MicroRNAs|KLK10 protein, human|*Kallikreins|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Sp1 Transcription Factor|LILRB1 protein, human|*Leukocyte Immunoglobulin-like Receptor B1|Histone Deacetylases|*Antigens, CD|Repressor Proteins|Cell Proliferation|Cell Line, Tumor|Upregulation|Sp1 protein, human 148 KLK10 32386481 Neoplasma 2020 10.4149/neo_2020_190814N758 0 0 0 169 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|KLK10 protein, human|*Kallikrein B'|Signal Transduction|Cell Proliferation|Colorectal Cancer|tripeptide aminopeptidase|HCT116 Cells|Glycolysis|*Aminopeptidases|HT29 Cells|Cell Line, Tumor|Apoptosis|Glucose 148 KLK10 32366393 Anticancer Res. 2020 10.21873/anticanres.14219 0 0 0 169 Humans|KLK15 protein, human|*Kallikreins|*MCF-7 Cells|*Gene Expression|Gene Expression Regulation, Neoplastic|RNA, Messenger 148 KLK10 32302973 Endocr. Relat. Cancer 2020 10.1530/ERC-18-0565 0 0 0 169 Humans|*Acromegaly|somatostatin receptor 5|Receptors, Somatostatin|SSTR2 protein, human|Growth Hormone-Secreting Pituitary Adenoma|Somatostatin|Octreotide|Pituitary Neoplasms|Human Growth Hormone|IGF1 protein, human|IGF-1|Genes, cdc|Ki-67 Antigen|CDH1 protein, human|E Cadherin|Antigens, CD|KLK10 protein, human|Kallikreins 148 KLK10 31904348 Clin. Biochem. 2020 10.1016/j.clinbiochem.2019.12.015 0 0 0 169 *Kallikrein B'|trypsin-like serine protease|RNA, Messenger|*Tissues, Lymphoid|*Protein Processing, Post-Translational 148 KLK15 32592124 Head Neck Pathol 2020 10.1007/s12105-020-01196-2 0 0 0 19 Humans|*Tissue Kallikreins|KLK15 protein, human|*Kallikrein B'|*Adenocarcinoma|Immunohistochemistry|Salivary Gland Neoplasms|*Polymerase Chain Reaction|mRNA|Gland, Salivary|Complementary DNA|KLK10 protein, human|KLK12 protein, human 53 KLK15 32366393 Anticancer Res. 2020 10.21873/anticanres.14219 0 0 0 19 Humans|KLK15 protein, human|*Kallikreins|*MCF-7 Cells|*Gene Expression|Gene Expression Regulation, Neoplastic|RNA, Messenger|Humans|KLK15 protein, human|*Kallikreins|*MCF-7 Cells|*Gene Expression|Gene Expression Regulation, Neoplastic|RNA, Messenger 53 KLK15 32334022 Gene 2020 10.1016/j.gene.2020.144708 0 0 0 19 Male|Humans|HEK293 Cells|kallikrein-related peptidase 3, human|*Kallikreins|KLK15 protein, human|*Sequencing, Next-Generation|Prostate Specific Antigen|Splicings, Alternative|Prostate|Prostate Cancer|RNA Splicing|Computational Biology|Cloning, Molecular|RNA, Messenger|Protein Isoforms|Cell Line, Tumor|Open Reading Frame 53 KLK15 31904348 Clin. Biochem. 2020 10.1016/j.clinbiochem.2019.12.015 0 0 0 19 *Kallikrein B'|trypsin-like serine protease|RNA, Messenger|*Tissues, Lymphoid|*Protein Processing, Post-Translational|*Kallikrein B'|trypsin-like serine protease|RNA, Messenger|*Tissues, Lymphoid|*Protein Processing, Post-Translational 53 KLK4 32626909 Int. J. Mol. Med. 2020 PMC7255463 10.3892/ijmm.2020.4598 0 0 0 334 Humans|Child|Mice|Animals|*Ameloblasts|*Amoxycillin|*Tight Junction Proteins|*Amelogenesis|*Tooth Calcification|Incisor|Scanning Electron Microscopy|Molars|Energy Dispersive X Ray Spectroscopy|Tooth Demineralization 240 KLK4 32592124 Head Neck Pathol 2020 10.1007/s12105-020-01196-2 0 0 0 334 Humans|*Tissue Kallikreins|KLK15 protein, human|*Kallikrein B'|*Adenocarcinoma|Immunohistochemistry|Salivary Gland Neoplasms|*Polymerase Chain Reaction|mRNA|Gland, Salivary|Complementary DNA|KLK10 protein, human|KLK12 protein, human 240 KLK4 32425594 Cancer Manag Res 2020 PMC7186775 10.2147/CMAR.S241372 0 0 0 334 Humans|Female|*RNA, Circular|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Signal Transduction|MIRN330 microRNA, human 240 KLK4 32369672 Oral Dis 2020 10.1111/odi.13384 0 0 0 334 Humans|Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive|Edar-Associated Death Domain Protein|*Molar|Ectodermal Dysplasia|Hypohidrotic Ectodermal Dysplasia|NF-kappa B|Dental Enamel 240 KLK4 32366393 Anticancer Res. 2020 10.21873/anticanres.14219 0 0 0 334 Humans|KLK15 protein, human|*Kallikreins|*MCF-7 Cells|*Gene Expression|Gene Expression Regulation, Neoplastic|RNA, Messenger 240 KLK6 32655372 Front Cell Neurosci 2020 PMC7324807 10.3389/fncel.2020.00166 0 0 0 379 Humans|Adult|*Kallikrein|Serine Proteases|*Disorders, Nervous System|Central Nervous System|Alzheimer Disease|KLK6 protein, human 265 KLK6 32630086 Diagnostics (Basel) 2020 10.3390/diagnostics10070444 0 0 0 379 *Neural Cell Adhesion Molecule L1|*Early Detection of Cancer|*Colorectal Neoplasms|Cancer Biomarkers|*Colonic Neoplasms|Prognosis|Kaplan-Meier Estimate|*Rectal Neoplasms|*Intestine, Large|*Screening 265 KLK6 32356177 J. Cancer Res. Clin. Oncol. 2020 10.1007/s00432-020-03224-8 0 0 0 379 *RNA, Long Noncoding|*RNA, Micro|*mRNA|*Prognosis|*Carcinoma, Non-Small-Cell Lung|*Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Lung Neoplasms|Gene Ontology|Transcriptome|Kaplan-Meier Estimate 265 KLK6 32158625 Oncoimmunology 2020 PMC7051188 10.1080/2162402X.2020.1731943 1 0 0 379 Tumor Suppressor Protein p53|Prognosis|Carcinoma, Squamous Cell|Biomarkers, Tumor|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Mutation|Kaplan-Meier Estimate 265 KLK6 32155135 J. Clin. Invest. 2020 PMC7260032 10.1172/JCI133159 0 0 0 379 Humans|*Receptor, PAR-1|KLK6 protein, human|*Kallikrein B'|*Skin|Receptor, PAR-2|Psoriasis|Signal Transduction|Cells, Cultured|Cytokines|*Eczema|*Exanthema 265 KLK6 32049988 PLoS ONE 2020 PMC7015415 10.1371/journal.pone.0229007 0 0 0 379 Humans|*mRNA|*Colorectal Cancer|*Lymph Node|*Colonic Neoplasms|Keratin-20|Lymphatic Metastasis|Prognosis|Biomarkers, Tumor 265 KLK9 32366393 Anticancer Res. 2020 10.21873/anticanres.14219 0 0 0 20 Humans|KLK15 protein, human|*Kallikreins|*MCF-7 Cells|*Gene Expression|Gene Expression Regulation, Neoplastic|RNA, Messenger|Humans|KLK15 protein, human|*Kallikreins|*MCF-7 Cells|*Gene Expression|Gene Expression Regulation, Neoplastic|RNA, Messenger 36 KLK9 31904348 Clin. Biochem. 2020 10.1016/j.clinbiochem.2019.12.015 0 0 0 20 *Kallikrein B'|trypsin-like serine protease|RNA, Messenger|*Tissues, Lymphoid|*Protein Processing, Post-Translational|*Kallikrein B'|trypsin-like serine protease|RNA, Messenger|*Tissues, Lymphoid|*Protein Processing, Post-Translational 36 krit1 32648916 J. Exp. Med. 2020 10.1084/jem.20200140 0 0 0 343 Mice|Animals|*Hemangioma, Cavernous, Central Nervous System|*Versicans|Endothelial Cells|*Proteolysis|KRIT1 protein, human|KRIT1 Protein|Apoptosis Regulatory Proteins|Signal Transduction|Kruppel-Like Transcription Factors|Carrier Proteins|MAP Kinase Signaling System|Disease Models, Animal|Mutation|Adamts5 protein, mouse|ADAMTS5 Protein 347 krit1 32596139 J Cerebrovasc Endovasc Neurosurg 2020 PMC7307612 10.7461/jcen.2020.22.1.15 0 0 0 343 Female|Humans|Adult|Familial cerebral cavernous malformation|*Hemangioma, Cavernous, Central Nervous System|*Syndrome|KRIT1 protein, human|KRIT1 Protein|Brain|Proto-Oncogene Proteins|Microtubule-Associated Proteins|Magnetic Resonance Imaging|Mutation|Genetic Predisposition|Phenotype|Dubowitz syndrome|Microcephaly|Eczema|Growth Disorders|Intellectual Disability|Facies 347 krit1 32524573 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_34 0 0 0 343 *Hemangioma, Cavernous, Central Nervous System|*Reactive Oxygen Species|*Fluorescence|KRIT1 protein, human|KRIT1 Protein|Oxidative Stress|Microtubule-Associated Proteins|Proto-Oncogene Proteins|Mutations|Cerebral Hemorrhage|Redox|Brain|Phenotypes 347 krit1 32524572 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_33 0 0 0 343 *Hemangioma, Cavernous, Central Nervous System|*Lactoylglutathione Lyase|Pyruvaldehyde|Glutathione|Oxidative Stress|*Spectrophotometry 347 krit1 32524570 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_31 0 0 0 343 Animals|Mice|Familial cerebral cavernous malformation|*Hemangioma, Cavernous, Central Nervous System|Endothelial Cells|KRIT1 protein, human|KRIT1 Protein|*Cell Signaling|Proto-Oncogene Proteins|Apoptosis Regulatory Proteins|Microtubule-Associated Proteins|Carrier Proteins|Membrane Proteins|Mutations|*Cytoplasm|Permeability, Vascular 347 krit1 32524569 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_30 0 0 0 343 Humans|*Cerebral Cavernous Malformations|*Sequestosome-1 Protein|KRIT1 protein, human|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Mutations|Microtubule-Associated Proteins|Membrane Proteins|Carrier Proteins|*Immunofluorescence|Genetic Predisposition to Disease|Autophagy|Signal Transduction|SQSTM1 protein, human 347 krit1 32524566 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_27 0 0 0 343 Animals|Humans|*Cavernous Malformation, Cerebral|KRIT1 protein, human|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Endothelial Cell|Phenotypes|Microtubule-Associated Proteins|Membrane Proteins|*Cell Proliferation|Carrier Proteins|Mutation 347 krit1 32524563 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_24 0 0 0 343 Humans|Mice|Animals|Endothelial Cells|KRIT1 protein, human|KRIT1 Protein|Hemangioma, Cavernous, Central Nervous System|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|*Signal Transduction|Microtubule-Associated Proteins|Membrane Proteins|Carrier Proteins|Mutation|Phenotype|Zebrafish 347 krit1 32524560 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_21 0 0 0 343 *Hemangioma, Cavernous, Central Nervous System|KRIT1 protein, human|KRIT1 Protein|radixin|Membrane Proteins|Microtubule-Associated Proteins|Proto-Oncogene Proteins|Carrier Proteins|Apoptosis Regulatory Proteins|Mutations|*Crystallography|moesin|Microfilament Proteins|Signal Transduction|Protein Binding|Repeat Domain, Ankyrin|Cerebral Cavernous Malformations 3|Micrognathism 347 krit1 32524559 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_20 0 0 0 343 KRIT1 protein, human|*KRIT1 Protein|*Two-Hybrid System Techniques|Cavernous Malformation, Cerebral|Microtubule-Associated Proteins|Proto-Oncogene Proteins|Mutations|RAP1A protein, human|rap1 GTP-Binding Proteins|cDNA|Capillaries|Genotype 347 krit1 32524558 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_19 0 0 0 343 Animals|Mice|*Endothelial Cells|KRIT1 protein, human|*KRIT1 Protein|*Mice, Knockout|Cavernous Malformation, Cerebral|*Brain|Microtubule-Associated Proteins|Proto-Oncogene Proteins|Mutation|Disease Models, Animal 347 krit1 32524557 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_18 0 0 0 343 Humans|Mice|Animals|*Hemangioma, Cavernous, Central Nervous System|*Animals, Newborn|Cre recombinase|KRIT1 protein, human|KRIT1 Protein|Proto-Oncogene Proteins|Apoptosis Regulatory Proteins|*Disease Models, Animal|Mutations|Microtubule-Associated Proteins|Cerebral Cavernous Malformations 2|Micrognathism|Membrane Proteins|Intellectual Disability|Ribs 347 krit1 32524551 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_12 0 0 0 343 Animals|Mice|*Cavernous Malformation, Cerebral|KRIT1 protein, human|*KRIT1 Protein|Microtubule-Associated Proteins|Oxidative Stress|Proto-Oncogene Proteins|Autophagy|Knockout Mouse|Redox|Homeostasis|Inflammation|Fibroblasts 347 krit1 32524550 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_11 0 0 0 343 Animals|Mice|*Hemangioma, Cavernous, Central Nervous System|*Endothelial Cells|KRIT1 protein, human|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Membrane Proteins|Carrier Proteins|Endothelium|Alleles|Brain 347 krit1 32524549 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_10 0 0 0 343 Humans|*Hemangioma, Cavernous, Central Nervous System|Endothelial Cells|KRIT1 protein, human|KRIT1 Protein|*Phenotype|Proto-Oncogene Proteins|Microtubule-Associated Proteins|Signal Transduction|siRNA|*Endothelium|Tumor Microenvironment 347 krit1 32524545 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_6 0 0 0 343 Humans|Familial cerebral cavernous malformation|*Hemangioma, Cavernous, Central Nervous System|*Genotype|KRIT1 protein, human|KRIT1 Protein|*Modifier Gene|Proto-Oncogene Proteins|Microtubule-Associated Proteins|Heterozygote|Mutations|Pedigree|Brain 347 krit1 32524544 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_5 0 0 0 343 Humans|*Hemangioma, Cavernous, Central Nervous System|*High-Throughput Nucleotide Sequencing|KRIT1 Protein|*Genetic Testing|Pedigree|Proto-Oncogene Proteins|Whole Exome Sequencing|Phenotype|Microtubule-Associated Proteins|Mutation|Carrier Proteins|Genome 347 krit1 32524543 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_4 0 0 0 343 *Hemangioma, Cavernous, Central Nervous System|Endothelial Cells|KRIT1 Protein|*Genetic Screening|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Mutation|Microtubule-Associated Proteins|Membrane Proteins|Carrier Proteins|Allele|RNA Splicing|Mutations, Germline 347 krit1 32524540 Methods Mol. Biol. 2020 10.1007/978-1-0716-0640-7_1 0 0 0 343 Humans|Animals|*Hemangioma, Cavernous, Central Nervous System|KRIT1 protein, human|KRIT1 Protein|Proto-Oncogene Proteins|Microtubule-Associated Proteins|Endothelial Cell|Mutation|Autophagy|Oxidative Stress|*Molecular Targeted Therapies|Redox 347 krit1 32515053 FASEB J. 2020 10.1096/fj.201902888R 0 0 0 343 Humans|*Endothelial Cells|FN1 protein, human|*Fibronectins|KRIT1 protein, human|*KRIT1 Protein|Cerebral Cavernous Malformations|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|*Phenotype|Membrane Proteins|Carrier Proteins|Microtubule-Associated Proteins|Mutation|CCM2 protein, human 347 KYNU 32659448 Theriogenology 2020 10.1016/j.theriogenology.2020.05.045 0 0 0 204 Female|Swine|Pregnancy|Animals|*Placentation|*Transcriptome|*Interferon|*Embryo Implantation|*Endometrium|*Transcriptome Analysis|Pregnancy, Animal|Uterus|*Regulatory Genes|*Antiviral Agents|Type II Interferon|Gene Ontology|Trophoblasts 68 KYNU 32406039 J. Mol. Neurosci. 2020 10.1007/s12031-020-01563-2 0 0 0 204 Animals|Rats|*Venlafaxine Hydrochloride|*Tryptophan|*Methylation|Leukocytes, Mononuclear|*Brain|Antidepressive Agents, Second-Generation|Depression|Indoleamine-Pyrrole 2,3,-Dioxygenase|Stress, Psychological|Hippocampus|Disease Models, Animal 68 KYNU 32384670 J Clin Med 2020 PMC7290775 10.3390/jcm9051360 0 0 0 204 Humans|*Crohn Disease|kynureninase|*Ileum|Colitis, Ulcerative|*Hydrolases|Colon|Kynurenine|*Ileal Disease|Biomarkers|Inflammatory Bowel Disease|*Mucositis|Intestinal Mucosa|Inflammation|Tryptophan|Case-Control Studies 68 KYNU 32346606 Mol Ther Oncolytics 2020 PMC7178007 10.1016/j.omto.2020.03.013 0 0 0 204 Humans|Tryptophan Oxygenase|Indoleamine-Pyrrole 2,3,-Dioxygenase|Tryptophan|Kynurenine|Cancer|Immunotherapy|Prognosis|Tryptophanase|Tumor Microenvironment 68 KYNU 32015132 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7035598 10.1073/pnas.1916588117 1 0 0 204 Pregnancy|Humans|Female|Mice|Animals|*Abortion, Spontaneous|*Gene-Environment Interaction|*NAD|Embryo Development 68 KYNU 32013628 Autoimmunity 2020 10.1080/08916934.2020.1722107 0 0 0 204 *Rheumatoid Arthritis|Synovial Membrane|Transcriptional Network|Gene Ontology|Protein Interaction Maps|Osteoarthritis|Gene Expression Profiling|miRNAs|Transcriptome|Databases, Genetic|Computational Biology|Gene Expression Regulation|Inflammation|STAT1 protein, human|STAT1 Transcription Factor 68 KYNU 31923704 Bone 2020 10.1016/j.bone.2019.115219 0 0 0 204 Humans|Catel Manzke syndrome|Hand Deformities, Congenital|Pierre Robin Sequence|*Syndrome|*Hand|Fingers|Abnormalities, Multiple|Homozygote|Heart Defects, Congenital|Mutations 68 LACRT 32274735 Adv. Exp. Med. Biol. 2020 10.1007/978-3-030-34521-1_31 0 0 0 69 SDC1 protein, human|*Syndecan-1|heparanase|*Dry Eye|*Glucuronidase|Tears|Glycoproteins|Eye Proteins|Autophagy|Signal Transduction 27 LAD1 32421906 J. Leukoc. Biol. 2020 10.1002/JLB.5HI0420-648R 0 0 0 596 Humans|Mice|Animals|Leukocyte adhesion deficiency type 1|Leukocyte-Adhesion Deficiency Syndrome|CD18 Antigens|Neutrophils|IL17A protein, human|IL-17|*Homeostasis|*Leukocyte Disorders|Inflammation|Cell Adhesion|*Periodontium|Integrins|Periodontitis|*Receptors, Nuclear 84 LAD1 32279896 Immunobiology 2020 10.1016/j.imbio.2020.151938 0 0 0 596 Humans|Aged|Leukocyte adhesion deficiency type 1|Pakistan|*Leukocyte-Adhesion Deficiency Syndrome|*CD18 Antigens|*Integrins|Mutation|Mutation, Missense 84 LAD1 32080965 EMBO Rep. 2020 PMC7132342 10.15252/embr.201949115 1 0 0 596 Humans|Mice|Animals|*Mesenchymal Stem Cells|Leukocyte adhesion deficiency type 1|*Leukocyte-Adhesion Deficiency Syndrome|Transforming Growth Factor beta1|Cell Differentiation|Cell Proliferation|Wound Healing 84 LAD1 31980681 Sci Rep 2020 PMC6981141 10.1038/s41598-020-57710-7 0 0 0 596 Animals|*Chickens|*Color|Chromosome Mapping|Quantitative Trait Loci|Feathers|Phenotype|Genomics|Genotype 84 LAMP3 32605588 Breast Cancer Res. 2020 PMC7329449 10.1186/s13058-020-01295-6 0 0 0 91 Humans|*MicroRNAs|*Extracellular Fluid|*Triple-Negative Breast Cancer|mRNA|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Transcriptome|*Neoplasm Grading|Tumor Microenvironment 124 LAMP3 32410873 Mediators Inflamm. 2020 PMC7201440 10.1155/2020/9238970 0 0 0 91 Humans|*Colitis, Ulcerative|Colon|Intestinal Mucosa|*Gene Expression Profiling|*Intestines|Cytokines|*Microarray Analysis|Transcriptomes|Biopsy|Real-Time Polymerase Chain Reaction 124 LAMP3 32312748 J. 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Radiopharm. 2020 10.1089/cbr.2019.3020 0 0 0 474 239 MACC1 32064885 Neoplasma 2020 10.4149/neo_2020_190719N651 0 0 0 474 *Cardia|*Cell Proliferation|*Apoptosis|MicroRNAs|Cell Movement|Gene Expression Regulation, Neoplastic|Downregulation|*Stomach Neoplasms|Cell Line, Tumor|CASP3 protein, human|Caspase 3|Upregulation|Transcription Factors|Binding Sites|*Neoplastic Processes|*Adenocarcinoma|*Colonic Neoplasms 239 MACC1 32058221 Biomed. Pharmacother. 2020 10.1016/j.biopha.2020.109986 2 0 0 474 *RNA, Long Noncoding|*Nasopharyngeal Carcinoma|SMAD2 protein, human|*Smad2 Protein|Gene Expression Regulation, Neoplastic|MicroRNAs|Prognosis|Cell Proliferation|Cell Line, Tumor|Disease Progression|Signal Transduction|Pancreatic Cancer|Nasopharyngeal Neoplasms 239 MACC1 32047570 J Cancer 2020 PMC6995387 10.7150/jca.38856 1 0 0 474 Carcinoma, Hepatocellular|Liver Neoplasms|Polymorphism, Single Nucleotide|Transcription Factors|Genotype|Colonic Neoplasms 239 MACC1 32031117 Indian J Pathol Microbiol 2020 10.4103/IJPM.IJPM_658_19 0 0 0 474 *Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Genes, Regulator|Transcription Factors|Messenger RNA 239 MACC1 31969498 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2020 10.11817/j.issn.1672-7347.2019.180391 0 0 0 474 Humans|Female|*Carcinoma, Ovarian Epithelial|*Cystadenocarcinoma, Serous|CD82 protein, human|KAI1 Protein|Ovarian Neoplasms|Prognosis|*Transcription Factors|Neoplasms, Glandular and Epithelial|Immunohistochemistry|Lymphatic Metastasis|*Colonic Neoplasms|Biomarkers, Tumor|Kaplan-Meier Analysis|Survival Rates|*Rectal Neoplasms|MACC1 protein, human 239 MACROD2 32527186 SLAS Discov 2020 10.1177/2472555220928911 0 0 0 58 ADP Ribosylation|Adenosine Diphosphate Ribose|Poly(ADP-ribose) Polymerases|ADP Ribosyltransferase|Posttranslational Modification|*Biological Assay|Hydrolysis 79 MACROD2 32427867 Sci Rep 2020 PMC7237415 10.1038/s41598-020-64623-y 0 0 0 58 Adenosine Diphosphate Ribose|MARylation|Posttranslational Modification|Poly(ADP-ribose) Polymerases|Signal Transduction|Cytoplasm|Cell Nucleus|Hydrolases 79 MACROD2 32257385 NPJ Genom Med 2020 PMC7113304 10.1038/s41525-020-0122-7 0 0 0 58 *Carcinoma, Hepatocellular|*Glycogen Synthase Kinase 3|*Liver Neoplasms|*Signal Transduction|beta Catenin|Epithelial-Mesenchymal Transition|*Catenins|Cell Line, Tumor|*Neoplastic Processes 79 MACROD2 32151005 Cancers (Basel) 2020 PMC7139919 10.3390/cancers12030604 0 0 0 58 *Hydrolases|ADP-Ribose|MARylation|Poly(ADP-Ribosyl)ation|*Carcinogenesis|Poly(ADP-ribose) Polymerases|Post-Translational Modifications|Cytoplasm|Site, Catalytic|Cancer 79 MACROD2 32081867 Sci Rep 2020 PMC7035424 10.1038/s41598-020-59922-3 0 0 0 58 Humans|*Autism Spectrum Disorder|*Exome|*DNA Copy Number Variations|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Pedigree|Cohort Studies|Neurodevelopmental Disorders|CNTNAP2 protein, human|Membrane Proteins|Nerve Tissue Proteins|VPS13B protein, human|Vesicular Transport Proteins|RNF113A protein, human|DNA-Binding Proteins|WWOX protein, human|WW Domain-Containing Oxidoreductase|Humans|*Autism Spectrum Disorder|*Exome|*DNA Copy Number Variations|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Pedigree|Cohort Studies|Neurodevelopmental Disorders|CNTNAP2 protein, human|Membrane Proteins|Nerve Tissue Proteins|VPS13B protein, human|Vesicular Transport Proteins|RNF113A protein, human|DNA-Binding Proteins|WWOX protein, human|WW Domain-Containing Oxidoreductase 79 MACROD2 31921812 Front Bioeng Biotechnol 2020 PMC6930883 10.3389/fbioe.2019.00407 1 0 0 58 Humans|*DNA Copy Number Variations|*Colorectal Cancer|Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genetic Predisposition to Disease|Genome, Human|*Colonic Neoplasms|MACROD2 protein, human|Hydrolases|DNA Repair Enzymes 79 MAGEC1 32626651 Front Oncol 2020 PMC7313421 10.3389/fonc.2020.00784 0 0 0 33 67 MAGEC1 32351899 Front Oncol 2020 PMC7174971 10.3389/fonc.2020.00538 0 0 0 33 Humans|Female|*Adenosarcoma|DNA Copy Number Variations|Mixed Tumor, Mullerian|*Mutation|Immunohistochemistry|*Sequencing, Whole Genome|Uterine Neoplasms|Biomarkers, Tumor|Chromosome Aberrations|Genetic Predisposition to Disease|Next Generation Sequencing 67 MALAT1 32667657 Nucleic Acids Res. 2020 10.1093/nar/gkaa585 0 0 0 22 Molecular Docking Simulation|RNA, Long Noncoding|Nucleic Acid Conformation|RNA Stability|*Adenocarcinoma of Lung|Ligands|Lung Neoplasms 1234 MALAT1 32663095 Cell Cycle 2020 10.1080/15384101.2020.1792667 0 0 0 22 *RNA, Long Noncoding|*Carcinoma, Renal Cell|*Sunitinib|*DNA Helicases|*RNA Recognition Motif Proteins|*Poly-ADP-Ribose Binding Proteins|*RNA Helicases|*Adenocarcinoma of Lung|MicroRNAs|Gene Expression Regulation, Neoplastic|Apoptosis|RNA, Small Interfering|Lung Neoplasms|Cell Line, Tumor|Cell Proliferation|Downregulation|*Neoplastic Processes|Upregulation 1234 MALAT1 32656611 Inflammation 2020 10.1007/s10753-020-01293-y 0 0 0 22 *Lipopolysaccharides|*Dexmedetomidine|*Downregulation|NF-kappa B|Up-Regulation|Inflammation|Apoptosis|Cytokines|RNA, Long Noncoding|Signal Transduction|MicroRNAs|Viability, Cell|Cell Proliferation|Sepsis|Cell Line 1234 MALAT1 32655805 Am J Transl Res 2020 PMC7344059 0 0 0 22 *RNA, Long Noncoding|*Brain Ischemia|*Stroke|*Lung Adenocarcinoma|*Apoptosis|PTEN protein, human|*PTEN Phosphohydrolase|*Adenocarcinoma|*Lung 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Markers 2020 PMC7317319 10.1155/2020/8521899 0 0 0 22 Humans|*RNA, Long Noncoding|*Aortic Aneurysm, Thoracic|*Biomarkers|MicroRNAs|Gene Expression Regulation, Neoplastic|RNA Interference|Cell Proliferation|Cell Line, Tumor 1234 MALAT1 32650527 Cancers (Basel) 2020 10.3390/cancers12071842 0 0 0 22 Humans|*Glioblastoma|*RNA, Long Noncoding|Quality of Life|Brain Neoplasms|Glioma|Prognosis|*Disease Progression|Gene Expression Regulation, Neoplastic|MicroRNAs|Epigenesis, Genetic|Biomarkers, Tumor|Brain 1234 MALAT1 32647564 Hepat Oncol 2020 PMC7338921 10.2217/hep-2020-0002 0 0 0 22 Humans|Child|*Sarcoma|*Hamartoma|*Liver Neoplasms|*Soft Tissue Neoplasms|Differential Diagnoses|Neoplasms, Germ Cell and Embryonal|Chromosomal Aberrations|Biomarkers, Tumor|Mesoderm|Liver 1234 MALAT1 32631421 J. Exp. Clin. Cancer Res. 2020 PMC7336474 10.1186/s13046-020-01627-6 0 0 0 22 Humans|Female|*Metformin|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Uterine Cervical Neoplasms|*Cell Proliferation|Hypoglycemic Agents|Apoptosis|Cell Line, Tumor|Long Non-Coding RNA|Xenograft Model Antitumor Assays 1234 MALAT1 32626943 Mol Med Rep 2020 PMC7339611 10.3892/mmr.2020.11196 0 0 0 22 *RNA, Long Noncoding|Neoplasm Recurrence, Local|*Cancer Stem Cell|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Liver Cancer|Signal Transduction|Upregulation|Cell Movement|Cell Line, Tumor|Apoptosis 1234 MALAT1 32623440 Med. Sci. Monit. 2020 10.12659/MSM.922672 0 0 0 22 Humans|*Adriamycin|*RNA, Long Noncoding|*Apoptosis|taxane|*Taxanes|Prognosis|MCF 7 Cells|*Adenocarcinoma of Lung|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Biomarkers, Tumor|Downregulation|Bridged-Ring Compounds|Lung Neoplasms 1234 MALAT1 32619204 Altern Ther Health Med 2020 0 0 0 22 dimethyl sulfone|*Curcumin|*Pomegranate|*Running|*Dimethyl Sulfoxide|*Sulfones|*Inflammation|Physical Endurance|Myalgia|C-Reactive Protein|Oxidative Stress|Dietary Supplements|Muscle, Skeletal|Biomarkers|Plant Extracts 1234 MALAT1 32606791 Onco Targets Ther 2020 PMC7311208 10.2147/OTT.S250796 0 0 0 22 Humans|*RNA, Long Noncoding|*Cancers|Reproducibility of Results|Biomarkers, Tumor|MicroRNAs|Case-Control Studies 1234 MALAT1 32602008 Nanoscale Res Lett 2020 PMC7324453 10.1186/s11671-020-03357-2 0 0 0 22 Humans|Animals|Rats|*RNA, Long Noncoding|*Vascular Endothelial Growth Factor A|Endothelial Cells|*Intracranial Aneurysm|*Lung Adenocarcinoma|MicroRNAs|Downregulation|Apoptosis|Cell Proliferation|Viability, Cell|*Adenocarcinoma|*Neoplastic Processes|Signal Transduction|*Lung Neoplasms|VEGFA protein, human|MIRN143 microRNA, human|MIRN143 microRNA, rat 1234 MALAT1 32596346 Biomed Res Int 2020 PMC7290873 10.1155/2020/6537462 0 0 0 22 Humans|*RNA, Long Noncoding|*Network, Gene|*Idiopathic Pulmonary Fibrosis|Gene Expression Profiling|Gene Expression Profiles|Lung|MicroRNAs|Bioinformatics|Protein Interaction Maps|RNA, Messenger|Upregulation|Transcription Factors|Regulatory Genes|Real Time Polymerase Chain Reaction|*Fibrosis|YBX1 protein, human|Y-Box-Binding Protein 1 1234 MALAT1 32591985 Neurochem. 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Rep. 2020 10.3892/or.2020.7535 0 0 0 161 *Esophageal Neoplasms|Esophageal Squamous Cell Carcinoma|*B-DNA|Carcinoma, Squamous Cell|Chemoradiotherapy|Cell Line, Tumor|MicroRNAs|DNA Repair|CpG Island|DNA End-Joining Repair 61 MAP3K10 32157176 Mol. Psychiatry 2020 10.1038/s41380-020-0702-z 0 0 0 161 Humans|*Smokers|*Nicotine|*Genome-Wide Association Study|CYP2A6 protein, human|Cytochrome P-450 CYP2A6|hydroxycotinine|Cotinine|Smoking|Smoking Cessation|Cigarettes|Tobacco|SNPs|Phenotype|Tobacco Smoking|Biomarkers 61 MAP3K10 31954518 Biochem. Biophys. Res. 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Cell 2020 PMC7181406 10.1016/j.devcel.2020.01.029 2 0 0 342 *Microtubule|Dyneins|Kinesin|tau Proteins|Protein Transport|Active Transport|Neurons|Cell Movement|Cytoplasm 26 MATN2 31963938 Int J Mol Sci 2020 PMC7013758 10.3390/ijms21020666 0 0 0 125 Mice|Animals|*Extracellular Matrix Proteins|*Matrilin Proteins|*Osteoarthritis|Mice, Knockout|*Musculoskeletal Abnormalities|Cartilage, Articular|Collagen|Glycoproteins|Bone and Bones|Extracellular Matrix|Osteogenesis|Phenotype|Matn1 protein, mouse|Matn4 protein, mouse 55 MATN2 31933763 Int J Clin Exp Pathol 2020 PMC6949765 0 0 0 125 Humans|Adolescent|*Matrilin Proteins|*Prognosis|*Osteosarcoma|Bone Neoplasms|Neoplasm Invasiveness|RNA, Long Noncoding|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|Transfection|MATN2 protein, human 55 MCM3AP 32678686 Br. J. Biomed. Sci. 2020 0 0 0 190 *RNA, Long Noncoding|MicroRNAs|Cell Line, Tumor|Intracellular Signaling Peptides and Proteins 67 MCM3AP 32606969 Cancer Manag Res 2020 PMC7319531 10.2147/CMAR.S245520 0 0 0 190 Humans|*RNA, Long Noncoding|*Nasopharyngeal Carcinoma|*Cell Proliferation|*Apoptosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Oncogenesis|Disease Progression|Nasopharyngeal Neoplasms|MCM3AP protein, human|Acetyltransferases|Intracellular Signaling Peptides and Proteins 67 MCM3AP 32485570 Biomed. Pharmacother. 2020 10.1016/j.biopha.2020.110289 0 0 0 190 Humans|Female|*RNA, Long Noncoding|MicroRNAs|Gene Expression Regulation, Neoplastic|*Disease Progression|centromere protein F|*Microfilament Proteins|*Chromosomal Proteins, Non-Histone|Cell Proliferation|Cell Line, Tumor|*Neoplastic Processes|Cell Movement|Intracellular Signaling Peptides and Proteins|Apoptosis|Upregulation|MCM3AP protein, human|Acetyltransferases|MIRN28 microRNA, human 67 MCM3AP 32319184 J. Peripher. Nerv. Syst. 2020 10.1111/jns.12377 0 0 0 190 Humans|*Charcot-Marie-Tooth Disease|*Phenotype|Mutations|Pedigree|Genotype-Phenotype Correlation|Sequencing, Whole Exome|Mutation, Missense|Intellectual Disability|MCM3AP protein, human|Acetyltransferases|Intracellular Signaling Peptides and Proteins 67 MCM3AP 32202298 Hum. Mol. Genet. 2020 PMC7297229 10.1093/hmg/ddaa051 0 0 0 190 Humans|Child|*Introns|*RNA Transport|*Active Transport, Cell Nucleus|Intracellular Signaling Peptides and Proteins|*Gene Expression|Nuclear Proteins|Cell Nucleus|Acetyltransferases|RNA, Messenger|*Phenotypes|*Biochemical Phenomena|ATXN7L3B protein, human|Transcription Factors 67 MCM3AP 32196596 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202003_20512 0 0 0 190 *Stomach Neoplasms|*Cell Proliferation|*Apoptosis|Long Non-Coding RNA|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|3' Untranslated Regions|*Stomach|Intracellular Signaling Peptides and Proteins|Disease Progression 67 MCM3AP 32193153 Mol Ther Nucleic Acids 2020 PMC7078492 10.1016/j.omtn.2020.01.016 0 0 0 190 Male|Mice|Animals|*Up-Regulation|*Methylation|Mice, Nude|Long Non-Coding RNA|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|MicroRNAs|Liver Neoplasms|Cell Proliferation|Downregulation|Apoptosis|Cell Line, Tumor|Cell Movement|Disease Progression|*Neoplastic Processes|*Proteins|Npy1r protein, mouse|Receptors, Neuropeptide Y 67 MCM3AP 31985002 Biosci. Rep. 2020 PMC7007402 10.1042/BSR20193794 0 0 0 190 Humans|Female|*RNA, Long Noncoding|*Downregulation|*Cell Proliferation|*Uterine Cervical Neoplasms|*Carcinoma, Squamous Cell|MicroRNAs|Hepatocellular Carcinoma|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Liver Neoplasms|MCM3AP protein, human|Acetyltransferases|Intracellular Signaling Peptides and Proteins|MIRN93 microRNA, human 67 MCM9 32647118 Cell Death Dis 2020 PMC7347845 10.1038/s41419-020-2736-1 0 0 0 93 Male|Meiosis|*DNA Mismatch Repair|Synapsis|*Cell Nucleus|Cell Cycle Proteins|Spermatocytes|DNA-Binding Proteins|Chromosomes|Genomic Instability 45 MCM9 32613604 Clin. Genet. 2020 10.1111/cge.13803 0 0 0 93 Humans|Female|*Primary Ovarian Insufficiency|*Exome|*Menopause, Premature|Sequencing, Whole Exome|NR5A1 protein, human|Steroidogenic Factor 1|Genome-Wide Association Study|Alleles|MCM9 protein, human|Minichromosome Maintenance Proteins 45 MCM9 32469048 Hum. Mol. Genet. 2020 10.1093/hmg/ddaa101 0 0 0 93 Humans|Male|Mice|Animals|Azoospermia, Nonobstructive|*Azoospermia|*Whole Exome Sequencing|*Oligospermia|*Chinese|*Cohort Studies|Genetic Predisposition to Disease|Infertility, Male|Polymorphism, Single Nucleotide|Spermatogenesis|CHD5 protein, human|DNA Helicases|Nerve Tissue Proteins|MCM9 protein, human|Minichromosome Maintenance Proteins|Mcm9 protein, mouse 45 MCM9 32449991 Hum. Mutat. 2020 10.1002/humu.24057 0 0 0 93 Humans|Early Detection of Cancer|*Colorectal Cancer|*Mutations|Adenomatous Polyposis Coli|Germ-Line Mutation|Genetic Association Studies|Genetic Predisposition to Disease|*Colonic Neoplasms|Heterozygote|ribosomal protein S20|Ribosomal Proteins|Promoter Regions, Genetic|Cohort Studies|LIMK2 protein, human|Lim Kinases|MCM9 protein, human|Minichromosome Maintenance Proteins|PTPN12 protein, human 45 MCM9 32295713 Biochem. Biophys. Res. 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Med. 2020 10.1142/S0192415X20500111 0 0 0 209 Humans|homoorientin|*Protons|*Cell Migration|*Lung Cancer|*Luteolin|Monocarboxylic Acid Transporters|Basigin|Cell Line, Tumor|Glycolysis|Symporters|RNA, Small Interfering|Muscle Proteins 66 MCTS1 31891569 Med. Sci. Monit. 2020 PMC6953439 10.12659/MSM.919690 0 0 0 209 *Carcinoma, Non-Small-Cell Lung|*Interleukin-6|*Lung Cancer|*T-Lymphocytes|*Signal Transduction|IL6R protein, human|Interleukin 6 Receptor|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplastic Stem Cells|Cell Line, Tumor|Cell Proliferation|Oncogenes 66 Meg3 32669097 BMC Cancer 2020 10.1186/s12885-020-07145-0 0 0 0 8 Humans|Female|*RNA, Long Noncoding|*Case-Control Studies|*Chinese|SNPs|Genetic Predisposition to Disease|Genotype|Risk Factors 810 Meg3 32647151 Sci Rep 2020 PMC7347880 10.1038/s41598-020-68017-y 0 0 0 8 Humans|Mice|Animals|Dogs|*Glioblastoma|ferric oxide|*Doxorubicin|Ferric Compounds|Blood-Brain Barrier|Antineoplastic Agents|Magnetite Nanoparticles|Glioma|Cell Line, Tumor|Magnetic Field|Permeability|ethylenediamine|Ethylenediamines|Tumor Microenvironment 810 Meg3 32642094 J Thorac Dis 2020 PMC7330306 10.21037/jtd-19-2472 0 0 0 8 Mice|Animals|*RNA, Long Noncoding|*RNA, Micro|*Down-Regulation|*Endothelial Cells|*Hypoxia-Inducible Factor 1|*Apoptosis|*Hypoxia|Signal Transduction|*Aorta 810 Meg3 32641696 Sci Rep 2020 PMC7343820 10.1038/s41598-020-68185-x 0 0 0 8 Humans|*Transcriptome|*Receptors, Cholinergic|*Myotubes|Agrin|Neuromuscular Junction|Myasthenia Gravis|Receptor Protein-Tyrosine Kinases|Synaptic Membranes|Autoantibodies|Acetylcholine 810 Meg3 32633352 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202006_21649 0 0 0 8 *Gallbladder Neoplasms|*RNA, Long Noncoding|*Apoptosis|*Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic 810 Meg3 32618397 J. Clin. Lab. Anal. 2020 10.1002/jcla.23369 0 0 0 8 *RNA, Long Noncoding|*DNA Methylation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Down-Regulation|Cell Movement|Cell Line, Tumor 810 Meg3 32614631 Adipocyte 2020 10.1080/21623945.2020.1789283 0 0 0 8 *RNA, Long Noncoding|*mRNA|Gene Regulatory Networks|MicroRNAs|Transcriptome|Diet, High-Fat|Protein Interaction Maps|Microarray Analysis|Obesity 810 Meg3 32612992 Front Cell Dev Biol 2020 PMC7308478 10.3389/fcell.2020.00461 0 0 0 8 *Non-Coding RNA|lncRNA|Genomic Imprinting|*Progenitor Cells, Mesenchymal|Intercellular Signaling Peptides and Proteins|Iodide Peroxidase|Calcium-Binding Proteins|MicroRNAs|Gene Expression Regulation, Neoplastic|Membrane Proteins|Epithelial-Mesenchymal Transition|Genetic Loci|Phenotype 810 Meg3 32608280 Arch. Physiol. Biochem. 2020 10.1080/13813455.2020.1784951 0 0 0 8 810 Meg3 32605923 J. Biol. Chem. 2020 10.1074/jbc.RA119.010946 0 0 0 8 Animals|Mice|*RNA, Long Noncoding|*Stroke|*Brain Ischemia|*Neurons|*Autophagy|Middle Cerebral Artery Occlusion|Up-Regulation|GRB2 protein, human|*Growth Factor Receptor-Bound Protein-2|MicroRNAs|Down-Regulation|MTOR protein, human|TOR Serine-Threonine Kinases|Cell Death|Signal Transduction|Glucose|Mice, Inbred C57BL|Disease Models, Animal 810 Meg3 32599124 Neuroscience 2020 10.1016/j.neuroscience.2020.06.026 0 0 0 8 *RNA, Long Noncoding|*Melatonin|*Neuroprotection|*Hydrogen Peroxide|*Neural Stem Cells|MicroRNAs|MAP2K1 protein, human|*MAP Kinase Kinase 1|Cell Proliferation|Upregulation|Transcriptional Activation 810 Meg3 32594338 Mol. Cell. Biochem. 2020 10.1007/s11010-020-03810-x 0 0 0 8 Humans|*RNA, Long Noncoding|*Up-Regulation|*Case-Control Studies|Diabetes Mellitus, Type 2|Leukocytes, Mononuclear|*Transcriptional Activation|MicroRNAs|Down-Regulation|Prognosis|Glucose|*Disease, Vascular 810 Meg3 32592473 Hum. Mol. Genet. 2020 10.1093/hmg/ddaa133 0 0 0 8 Pregnancy|Humans|Male|Female|Mice|Animals|Uniparental disomy, paternal, chromosome 14|*Uniparental Disomy|Genomic Imprinting|*Genotypes|*Chromosomes, Human, Pair 14|*Abnormalities, Multiple|Phenotype|DNA Methylation|lncRNA|Calcium-Binding Proteins|Membrane Proteins|Chromosome|snoRNA|*Musculoskeletal Abnormalities|miRNAs|Fathers 810 Meg3 32578033 J. Mol. Neurosci. 2020 10.1007/s12031-020-01646-0 0 0 0 8 Humans|Male|Female|*RNA, Long Noncoding|*Down-Regulation|*Multiple Sclerosis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Up-Regulation|Biomarkers, Tumor|Cell Line, Tumor 810 Meg3 32546215 Clin Epigenetics 2020 PMC7298762 10.1186/s13148-020-00865-x 0 0 0 8 Humans|*Silver-Russell Syndrome|DNA Copy Number Variations|*Phenotype|Genomic Imprinting|Uniparental Disomy|DNA Methylation|Epigenesis, Genetic|IGF2 protein, human|IGF-2|Transcription Factors|*Biochemical Phenomena 810 Meg3 32545342 Int J Mol Sci 2020 PMC7313458 10.3390/ijms21114182 0 0 0 8 Humans|*Insulin Resistance|Diabetes Mellitus, Type 2|*Non-Coding RNA|Long Non-Coding RNA|*Liver|RNA, Micro|*Biomarkers|Insulin|Metabolic Syndrome|*Early Diagnosis 810 Meg3 32537021 Exp Ther Med 2020 PMC7281984 10.3892/etm.2020.8723 0 0 0 8 Humans|*RNA, Long Noncoding|*DNA Methylation|*Multiple Myeloma|*Promoter Regions, Genetic|Azacitidine|Cell Proliferation|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Down-Regulation|Cell Line, Tumor 810 Meg3 32520926 Med. Sci. Monit. 2020 PMC7301678 10.12659/MSM.922486 0 0 0 8 Humans|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Periodontal Ligament|RNA, Long Noncoding|MicroRNAs|Apoptosis|Upregulation|Apoptosis Regulatory Proteins|Lipopolysaccharides|Cell Proliferation|Cell Survival|Periodontitis|Transcriptional Activation|MIRN143 microRNA, human 810 Meg3 32519748 Biosci. Rep. 2020 PMC7327180 10.1042/BSR20194370 0 0 0 8 Humans|*RNA, Long Noncoding|*Endothelial Cells|JAK2 protein, human|*Janus Kinase 2|STAT3 protein, human|*STAT3 Transcription Factor|*MicroRNAs|*Apoptosis|Cell Proliferation|Signal Transduction|*Retina|Diabetic Retinopathy|*Cell Death|Inflammation|Glucose|SOCS6 protein, human|Suppressor of Cytokine Signaling Proteins 810 Meg3 32509057 Int J Clin Exp Pathol 2020 PMC7270692 0 0 0 8 Humans|Female|*RNA, Long Noncoding|*Cell Survival|*MicroRNAs|*Apoptosis|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Cycle|MIRN205 microRNA, human 810 megf10 32529675 Bioessays 2020 10.1002/bies.201900185 0 0 0 113 Animals|Mice|*Caenorhabditis elegans|Axons|Nerve Regeneration|Caenorhabditis elegans Proteins|Genes, Helminth|*Neurons|Apoptosis Regulatory Proteins|Apoptosis|Drosophila|Cytoskeletal Proteins|Animals, Genetically Modified|Membrane Proteins|Carrier Proteins|Phagocytosis|Gene Expression Regulation, Developmental|Draper protein, Drosophila 60 METRNL 32604889 Nutrients 2020 PMC7353393 10.3390/nu12061899 0 0 0 81 *Adipokines|*Exercise|*Inflammation|MSTN protein, human|Myostatin|Adipose Tissue|Leptin|Adipose Tissue, White|Obesity|Muscle, Skeletal|IL15 protein, human|IL-15|fibroblast growth factor 21|Fibroblast Growth Factors|Insulin Resistance|Energy Expenditure|Signal Transduction 47 METRNL 32598020 Endokrynol Pol 2020 10.5603/EP.a2020.0038 0 0 0 81 Humans|*Insulin Resistance|Diabetes Mellitus, Type 2|Adipokine|Blood Glucose|Obesity|Body Mass Index|subfatin protein, human 47 METRNL 32594095 Med. Sci. Monit. 2020 10.12659/MSM.924564 0 0 0 81 Humans|*Myocardial Reperfusion Injury|*Endoplasmic Reticulum Stress|*Myocytes, Cardiac|*AMP-Activated Protein Kinases|*Apoptosis|*Signal Transduction|Cell Hypoxia|Viability, Cell|Downregulation|Cells, Cultured|PAK2 protein, human|p21-Activated Kinases 47 METRNL 32563939 Diabetes Metab Syndr 2020 10.1016/j.dsx.2020.05.031 0 0 0 81 Adult|Humans|*Insulin Resistance|Iran|*Body Composition|Sedentary Behavior|Blood Glucose|Insulin|Diabetes Mellitus, Type 2|Adipokines|Physical Activity|Body Mass Index|Obesity|Risk Factors 47 METRNL 32407372 PLoS ONE 2020 PMC7224509 10.1371/journal.pone.0233087 0 0 0 81 Mice|Animals|*Mice, Inbred C57BL|Nonalcoholic Fatty Liver Disease|Diet, High-Fat|Liver|Quantitative Trait Locus|Mice, Inbred Strains|Lipid Metabolism|Adipose Tissue|Obesity|Gene Expression|Adipokines|Triglycerides|Mice, Knockout 47 METRNL 32330176 PLoS ONE 2020 PMC7182262 10.1371/journal.pone.0231943 0 0 0 81 Pregnancy|Female|Humans|*Polycystic Ovary Syndrome|*Case-Control Studies|Insulin Resistance|Adiponectin|Insulin|Blood Glucose|Body Mass Index|Testosterone|Obesity|C-Reactive Protein|Adipokine|Fasting 47 METRNL 32265491 Acta Pharmacol. Sin. 2020 10.1038/s41401-020-0368-8 0 0 0 81 Mice|Animals|*Cholesterol, HDL|Diabetes Mellitus, Type 2|*Triglycerides|Low Density Lipoprotein Cholesterol|Diet, High-Fat|Dietary Fats|Lipids|Nonesterified Fatty Acids|Adipokines|Dyslipidemia|Liver|Adiposity 47 METRNL 32196931 FEBS J. 2020 10.1111/febs.15301 1 0 0 81 Mice|Animals|Diabetes Mellitus, Type 2|*Muscle Fibers, Skeletal|Insulin Resistance|Diet, High-Fat|Obesity|AMP-Activated Protein Kinases|Glucose|Muscle, Skeletal|Phosphorylation|HDAC5 protein, human|Histone Deacetylases|*Carbohydrate Metabolism 47 METRNL 32044349 Diabetes Res. Clin. Pract. 2020 10.1016/j.diabres.2020.108068 2 0 0 81 Humans|*Intra-Abdominal Fat|*Diabetes Mellitus, Type 2|*Obesity, Visceral|*Obesity|Body Mass Index|Chinese|Risk Factors 47 METRNL 31960164 Lung 2020 10.1007/s00408-020-00327-4 0 0 0 81 *Adipokine|*Chronic Obstructive Pulmonary Disease|Lung|Smoking|Diabetes Mellitus, Type 2|Inflammation|Anti-Inflammatory Agents 47 METRNL 31949292 Acta Pharmacol. Sin. 2020 10.1038/s41401-019-0343-4 0 0 0 81 Mice|Animals|*Colitis, Ulcerative|Dextran Sulfate|Colitis|*Autophagy|Intestinal Epithelium|Colon|*Intestines|*Cells, Epithelial|Mice, Inbred C57BL|Signal Transduction 47 MFSD8 32412666 Mol Genet Genomic Med 2020 PMC7336735 10.1002/mgg3.1228 1 0 0 93 Dogs|Animals|*Neuronal Ceroid-Lipofuscinoses|*Prevalence|Russia|*Heterozygote|Homozygote|Pedigree|Membrane Transport Proteins|Membrane Proteins|Mutation|Dog Diseases|Seizures 51 MFSD8 32087303 Cell. Signal. 2020 10.1016/j.cellsig.2020.109572 0 0 0 93 Humans|Ceroid lipofuscinosis, neuronal 5|*Neuronal Ceroid-Lipofuscinoses|*Dictyostelium|*Cathepsin D|MFSD8 protein, human|*Membrane Transport Proteins|Lysosomes|Mutations|CLN5 protein, human|Membrane Proteins 51 MFSD8 31906755 Int. J. Neurosci. 2020 10.1080/00207454.2019.1694020 0 0 0 93 51 MICAL2 32659284 Toxicol. Appl. Pharmacol. 2020 10.1016/j.taap.2020.115125 0 0 0 153 *RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|SHC1 protein, human|*Src Homology 2 Domain-Containing, Transforming Protein 1|Zinc Finger E-box-Binding Homeobox 1|RNA, Micro|*Fibrosis, Liver|Transforming Growth Factor beta1|Carbon Tetrachloride|Cells, Cultured 22 MICAL2 32360180 Cancer Lett. 2020 10.1016/j.canlet.2020.04.019 0 0 0 153 Humans|Epithelial-Mesenchymal Transition|*Lung Adenocarcinoma|Cell Migration|Cell Proliferation|Adenocarcinoma|Lung Neoplasms|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|*Neoplastic Processes|*Active Transport, Cell Nucleus 22 MICAL2 31949908 IUCrJ 2020 PMC6949599 10.1107/S2052252519015409 1 0 0 153 Humans|Mice|Animals|calponin|dimethylaniline monooxygenase (N-oxide forming)|*Microfilament Proteins|*Calcium-Binding Proteins|F-Actin|*Kinetics|Actin Cytoskeleton|Mixed Function Oxygenases|Crystallography, X-Ray|Oxidoreductases|Models, Molecular|Oxidation-Reduction|MICAL1 protein, human|Cytoskeletal Proteins|Adaptor Proteins, Signal Transducing|LIM Domain Proteins|MICAL3 protein, human 22 MIEN1 32305633 Gene 2020 10.1016/j.gene.2020.144678 0 0 0 102 Humans|*Stomach Neoplasms|*RNA, Circular|*Upregulation|Cell Proliferation|MicroRNAs|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Prognosis|Cell Line, Tumor|Cell Movement|Disease Progression|*Transcriptional Activation|Biomarkers, Tumor|Triple-Negative Breast Cancer|MIEN1 protein, human|Neoplasm Proteins|Intracellular Signaling Peptides and Proteins 33 MIPEP 32241877 Plant Physiol. 2020 PMC7271809 10.1104/pp.20.00197 1 0 0 43 *miRNA|Arabidopsis Proteins|Arabidopsis|Indoleacetic Acids|Hypocotyl|Gene Expression Regulation, Plant|Plant Roots|peptide B 29 MIPEP 32165249 Fish Shellfish Immunol. 2020 10.1016/j.fsi.2020.03.008 0 0 0 43 Animals|*Streptococcus agalactiae|*Oreochromis niloticus|*Transcriptome|*Proteome|*Virulence|Proteomics|DNA Helicases|Poly-ADP-Ribose Binding Proteins|RNA Helicases|RNA Recognition Motif Proteins|Streptococcal Infections|Tilapia|Fish Diseases|Transcriptome Analysis|Aquiculture 29 MIPEP 32115557 Yakugaku Zasshi 2020 10.1248/yakushi.19-00193-2 0 0 0 43 Mice|Animals|*Caloric Restriction|*Adipose Tissue, White|*Aging|Sterol Regulatory Element Binding Protein 1c|Mitochondrial Biogenesis|Lifespan|Sirtuin 3|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|IGF1 protein, human|Insulin-Like Growth Factor I|Mice, Knockout|Mitochondria|Growth Hormone|mitochondrial intermediate peptidase|Metalloendopeptidases|Fatty Acids|Signal Transduction|Oxidative Stress 29 MIPEP 32094149 Genetics 2020 PMC7153937 10.1534/genetics.119.302851 0 0 0 43 Humans|*Antibiotic|Proteomics|Endopeptidase Clp|TIC10 compound|Heterocyclic Compounds, 4 or More Rings|Proteolysis|Bacterial Proteins|Cell Line, Tumor|*Hydrolases|ClpP protein, human 29 MIR135B 32196445 Curr Pharm Biotechnol 2020 10.2174/1389201021666200320135139 0 0 0 0 Humans|*MicroRNAs|*Multiple Myeloma|*Bone Marrow|Gene Expression Profiling|Biomarkers|Real-Time Polymerase Chain Reaction|*Cytogenetic Aberrations|Case-Control Studies 26 MIR135B 32076030 Sci Rep 2020 PMC7031337 10.1038/s41598-020-59789-4 0 0 0 0 Humans|*Neurofibromatosis 1|*MicroRNAs|*Neurofibrosarcoma|*Nerve Sheath Neoplasms|Plexiform Neurofibromas|Gene Expression Regulation, Neoplastic|Downregulation|Signal Transduction|Gene Expression Profiling|Cell Proliferation|Cell Transformation, Neoplastic 26 MIR17HG 32584970 Blood 2020 10.1182/blood.2020005289 0 0 0 93 Humans|Adult|*Lymphoma, Mantle-Cell|*Epigenomics|*Genomics|Prognosis|Mutation|Translocation, Genetic|Chromatin|B Cell Lymphoma|Biomarkers, Tumor|Exome|Genes, cdc|Oncogenesis 62 MIR17HG 32558936 J. Pathol. 2020 10.1002/path.5493 0 0 0 93 Humans|Child|*Rhabdoid Tumor|CCND1 protein, human|*Cyclin D1|*Up-Regulation|SMARCB1 protein, human|*SMARCB1 Protein|Transcription Factors|Teratoma|*Activation, Transcription|Chromatin Assembly and Disassembly|*Central Nervous System Neoplasms|Phenotype 62 MIR17HG 32473250 Gene 2020 10.1016/j.gene.2020.144816 0 0 0 93 Humans|Female|Oculodigitoesophagoduodenal syndrome|Microcephaly|Intellectual Disability|Limb Deformities, Congenital|Tracheoesophageal Fistula|Dwarfism|Eyelids|Comparative Genomic Hybridization|Phenotype|MicroRNAs|Syndrome|*Chromosome Structures|GPC5 protein, human|Glypicans|MIRN17 microRNA, human 62 MIR17HG 32228546 BMC Pulm Med 2020 PMC7104535 10.1186/s12890-020-1112-3 0 0 0 93 *Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|*Downregulation|*Upregulation|MicroRNAs|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Transcriptional Activation 62 MIR17HG 32068173 World Neurosurg 2020 10.1016/j.wneu.2020.02.039 0 0 0 93 Humans|*Meningioma|Meningeal Neoplasms|Neoplasm Grading|Meninges|Retrospective Studies|Neoplasm Recurrence, Local 62 MIR17HG 31976095 Case Rep Genet 2020 PMC6949681 10.1155/2019/7250838 0 0 0 93 Humans|Chromosome 13 ring|*Ring Chromosomes|*Mosaicism|*Chromosomes, Human, Pair 13|Karyotyping|Comparative Genomic Hybridization|Microcephaly|In Situ Hybridization, Fluorescence|Abnormalities, Multiple|Intellectual Disability|Karyotype|Agenesis, Corpus Callosum|Phenotype|Syndrome 62 MIR17HG 31924195 Respir. Res. 2020 PMC6954528 10.1186/s12931-019-1257-x 0 0 0 93 *RNA, Long Noncoding|RNA, Micro|mRNA|Prognosis|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Ontology|Kaplan-Meier Estimate|*Asthma 62 MIR22HG 32569434 FEBS Open Bio 2020 10.1002/2211-5463.12913 0 0 0 85 Humans|*RNA, Long Noncoding|*Leukocytes, Mononuclear|*Rheumatoid Arthritis|*Autophagy|Gene Expression Profiling|Sequencing, RNA|Receiver Operating Characteristic|Biomarkers|Gene Expression Regulation|*Apoptosis|*Leukocytes|Case-Control Studies 37 MIR22HG 32500915 Biosci. Rep. 2020 PMC7313441 10.1042/BSR20193991 0 0 0 85 *Urinary Bladder Neoplasms|PTEN protein, human|*PTEN Phosphohydrolase|*Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Proto-Oncogene Proteins c-akt|Cell Movement|Up-Regulation|Apoptosis 37 MIR22HG 32411397 Environ Epigenet 2020 PMC7211362 10.1093/eep/dvaa003 0 0 0 85 Humans|Child|Pregnancy|Female|*Birth Weight|*Cadmium|*RNA, Long Noncoding|*Placenta|Fetal Growth|Maternal-Fetal Exchange|Maternal Exposure|Environmental Pollutants|Metals, Heavy|*Delivery, Obstetric|Rhode Island 37 MIR22HG 32377223 Comput Math Methods Med 2020 PMC7195652 10.1155/2020/3651051 0 0 0 85 *RNA, Long Noncoding|*Prognosis|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Biomarkers, Tumor|*Thyroid Cancer|RNA, Messenger 37 MIR22HG 32339124 Comput. Biol. Med. 2020 10.1016/j.compbiomed.2020.103690 0 0 0 85 Humans|Editing, RNA|Adenosine Deaminase|RNA-Binding Proteins|*Cancers|Disease Progression|ADAR1 protein, human 37 MIR22HG 32233607 Math Biosci Eng 2020 10.3934/mbe.2020093 0 0 0 85 Humans|Male|*RNA, Long Noncoding|*Downregulation|*Prostate Cancer|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Cell Movement|Signal Transduction|Gleason Score|Kaplan-Meier Estimate|Disease-Free Survival 37 MIR22HG 32127004 Mol. Cancer 2020 PMC7055097 10.1186/s12943-020-01174-w 1 0 0 85 Humans|*Colorectal Cancer|*Genes, Tumor Suppressor|RNA, Long Noncoding|*Signal Transduction|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|Epithelial-Mesenchymal Transition|Apoptosis|*Colonic Neoplasms|*Immunotherapy 37 MIR22HG 32099468 Cancer Manag Res 2020 PMC7002755 10.2147/CMAR.S231796 0 0 0 85 Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Prognosis|Neoplasm Recurrence, Local|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Gene Regulatory Networks|Kaplan-Meier Estimate 37 MIR22HG 32094308 Mol. Cell. Biol. 2020 PMC7189097 10.1128/MCB.00496-19 0 0 0 85 Humans|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|*Down-Regulation|Cell Proliferation|RNA, Long Noncoding|MicroRNAs|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|*Disease Progression|Cell Movement|Upregulation|Cell Line, Tumor|Signal Transduction|*Genes, Regulator|Transcriptional Activation|E2F6 protein, human|E2F6 Transcription Factor 37 MIR22HG 31934786 DNA Cell Biol. 2020 10.1089/dna.2019.5161 0 0 0 85 Humans|*RNA, Long Noncoding|*Stomach Neoplasms|*Prognosis|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|MicroRNAs|RNA, Messenger|Gene Ontology|Biomarkers, Tumor|Databases, Genetic|Survival Analysis|Noncoding RNA|Profile, Gene Expression|Disease Progression|Kaplan-Meier Estimate|UBE2Q1 protein, human|Ubiquitin-Conjugating Enzymes 37 MIR22HG 31891366 Brain 2020 PMC7009478 10.1093/brain/awz406 1 0 0 85 Humans|*RNA, Long Noncoding|*Glioblastoma|Wnt Signaling Pathway|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|beta Catenin|*Disease Progression|*Catenins|Cell Line, Tumor|Epithelial-Mesenchymal Transition 37 Mkx 32587790 PeerJ 2020 PMC7304430 10.7717/peerj.8740 0 0 0 126 Humans|*Tenocytes|*Insulin Resistance|Diabetes Mellitus, Type 2|*Tendinopathy|Achilles Tendon|TNF protein, human|Tumor Necrosis Factor alpha|Cells, Cultured 50 Mkx 32566118 J Tissue Eng 2020 PMC7288803 10.1177/2041731420930379 0 0 0 126 Animals|Rabbits|Osteogenesis|*Mesenchymal Stem Cells|*Bone Regeneration|*Bone|Cell Differentiation|Tissue Scaffolds|Tissue Engineering 50 Mkx 32558993 FASEB J. 2020 10.1096/fj.201902942RR 0 0 0 126 Rats|Animals|*Gene Expression|Tendon Injuries|*Tenotomy|Wound Healing|*Adipocytes|Rupture|Collagen|Collagen Type I|Hydroxyproline|Tendons|Stem Cells 50 Mkx 32211592 JOR Spine 2020 PMC7084052 10.1002/jsp2.1081 0 0 0 126 Animals|*Transcription Factors|*Intervertebral Disk|Intervertebral disc disease|Intervertebral Disc Degeneration|Nucleus Pulposus|Mesenchymal Stem Cell Transplantation|Cell Differentiation|Mesenchymal Stem Cells|Regeneration|Herniated Disc 50 Mkx 32148523 Stem Cells Int 2020 PMC7053469 10.1155/2020/9123281 0 0 0 126 Humans|*Mesenchymal Stem Cells|*Copper|*Protein-Lysine 6-Oxidase|*Cell Differentiation|Tendons|Stem Cells|Tissue Engineering|Adipose Tissue 50 Mkx 32046263 Int J Mol Sci 2020 PMC7037627 10.3390/ijms21031132 0 0 0 126 *Anterior Cruciate Ligament|dilactide|*Dioxanes|Tissue Engineering|Tissue Scaffolds|Anterior Cruciate Ligament Injuries|*Fibroblasts|Polyesters|*Poly A|Autografts|Transplantation, Autologous 50 Mkx 31930553 J. Orthop. Res. 2020 10.1002/jor.24587 0 0 0 126 Dogs|Animals|*Tenocytes|*Exosomes|Tendon|Tendon Injuries|Cell Proliferation|Collagen|Tendinopathy|Cells, Cultured|Cell Differentiation|Wound Healing|Collagen Type I 50 Mkx 31899537 Eur Cell Mater 2020 PMC7027376 10.22203/eCM.v039a01 0 0 0 126 Humans|*Annulus Fibrosus|*Polyurethanes|*Collagen|Tissue Engineering|Tissue Scaffolds|Intervertebral Disc|Collagen Type I|Extracellular Matrix|Intervertebral Disc Degeneration|*Transforming Growth Factor|Transforming Growth Factor beta1|Cell Differentiation|Cells, Cultured|Cell Proliferation|*B-Lymphocytes|Cell Survival|*Phenotype 50 MN1 32650833 Acta Neuropathol Commun 2020 PMC7350623 10.1186/s40478-020-00984-9 0 0 0 187 Child|Humans|*Central Nervous System Neoplasms|Neoplasms, Neuroepithelial|Brain Neoplasms|*Brain|*Genes, Neoplasm|Proto-Oncogene Proteins|Repressor Proteins|Ewings Sarcoma|BCOR protein, human|FOXR2 protein, human|Forkhead Transcription Factors|MN1 protein, human|Tumor Suppressor Proteins 503 MN1 32627877 Adv. Mater. Weinheim 2020 10.1002/adma.202001419 0 0 0 187 *Sodium|*Electric Power Supplies|*Cathode|*Ions|Electrolytes 503 MN1 32611032 Rev Sci Instrum 2020 10.1063/1.5128949 0 0 0 187 *Magnetic Fields|Magnetics|Temperature|Iron|Models, Molecular 503 MN1 32601775 Brain Tumor Pathol 2020 10.1007/s10014-020-00372-0 0 0 0 187 Humans|Male|Female|Adolescent|Astroblastoma|*Central Nervous System Neoplasms|Brain Neoplasms|Tumor Suppressor Proteins|Brain|MN1 protein, human 503 MN1 32576961 Leukemia 2020 10.1038/s41375-020-0929-3 0 0 0 187 Humans|Mice|Animals|*Leukemia, Myelomonocytic, Chronic|*Heterografts|*Leukemia, Myelomonocytic, Juvenile|Genes, ras|Azacytidine|*Disease Models, Animal|Mutation|*Treatment Outcome|Protein Kinase Inhibitors 503 MN1 32567130 Small 2020 10.1002/smll.202001884 0 0 0 187 *Ionic Liquids|*Nanopores|Lithium|Electric Power Supplies|Electrodes|Titanium 503 MN1 32533098 Oncogene 2020 10.1038/s41388-020-1340-2 0 0 0 187 Humans|Mice|Animals|*Hematopoietic Stem Cells|Hematopoiesis|Leukemia, Myeloid, Acute|Bone Marrow Cells|Cell Differentiation|Cell Proliferation|*Cell Division|Embryonic Development 503 MN1 32527063 Int J Mol Sci 2020 PMC7312406 10.3390/ijms21114125 0 0 0 187 *Hedgehog Proteins|*Zinc Finger Protein GLI1|*Motor Neuron|*Cell Differentiation|*Signal Transduction|Zinc Finger Protein Gli3|Zinc Finger Protein Gli2|Transcription Factors|Kruppel-Like Transcription Factors|Trans-Activators|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|*Neurogenesis|Receptors, Retinoic Acid 503 MN1 32484269 Adv. Mater. Weinheim 2020 10.1002/adma.202002043 0 0 0 187 *Physical Phenomena|Diagnostic Tests, Routine|Magnetic Phenomena 503 MN1 32483292 Sci Rep 2020 PMC7264220 10.1038/s41598-020-64867-8 0 0 0 187 Electrodes 503 MN1 32434915 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7293653 10.1073/pnas.2000529117 0 0 0 187 Photosystem II|Water|Oxygen|Spinacia oleracea|Oxidation-Reduction|Manganese|Photosynthesis|Models, Molecular 503 MN1 32422513 J. Hazard. Mater. 2020 10.1016/j.jhazmat.2020.122671 0 0 0 187 *Vanadates|*Catalysis|Ammonia|Oxides|Oxidation-Reduction|*Metals|Titanium|Temperature|ammonium bisulfate|Ammonium Sulfate 503 MN1 32410377 Angew. Chem. Int. Ed. Engl. 2020 10.1002/anie.202004853 0 0 0 187 Humans|*Lithium|*Electric Power Supplies|*Electrolytes|Cathode|*Metals|Ions|Ethnic Groups 503 MN1 32374174 J Phys Chem Lett 2020 10.1021/acs.jpclett.0c00794 0 0 0 187 *Water|Photosystem II|*Oxidation-Reduction|Manganese|Electrons|Models, Molecular|Oxygen|Lasers|*Electronic 503 MN1 32373850 Phys Chem Chem Phys 2020 10.1039/d0cp01380c 0 0 0 187 *Water|Photosystem II|Photosynthesis|Manganese|Dioxygen|Electron Spin Resonance Spectroscopy|Oxidation-Reduction|Calcium 503 MN1 32353096 Dalton Trans 2020 10.1039/d0dt00305k 0 0 0 187 *Antimony|Manganese|Magnetic|Crystallization|Neutron Diffraction|Ferromagnets|Crystallography, X-Ray|Models, Molecular|Temperature 503 MN1 32332771 Sci Rep 2020 PMC7181668 10.1038/s41598-020-63223-0 0 0 0 187 *Magnetic|Magnetic Fields|*Physical Phenomena 503 MN1 32304252 Chemistry 2020 10.1002/chem.202001055 0 0 0 187 *Nickel|*Manganese|*Oxygen|*Urea|cobalt hydroxide|*Cobalt|hydroxide ion|*Hydroxides|*Oxidation-Reduction|Water|Anode|Catalysis|Electrochemistry|Kinetics|*Biological Phenomena 503 MN1 32287450 Thin Solid Films 2020 PMC7111822 10.1016/j.tsf.2019.137637 0 0 0 187 *Cations|X-Ray Diffraction|Oxides|Temperature 503 MN1 32286730 ChemSusChem 2020 10.1002/cssc.202000559 0 0 0 187 Lithium|Electric Power Supplies|Anodes|Graphite|Microscopy, Electron, Scanning|Carbon|Ions|Zinc 503 mnx1 32615233 Neuroscience 2020 10.1016/j.neuroscience.2020.06.028 0 0 0 116 Humans|Induced Pluripotent Stem Cells|*Motor Neurons|*Pluripotent Stem Cell|Cell Differentiation|*Neurons, Efferent|Cells, Cultured|Genes, Reporter|Cell Line|Cholinergic Agents 159 mnx1 32571425 Orphanet J Rare Dis 2020 PMC7310025 10.1186/s13023-020-01442-4 0 0 0 116 Humans|Currarino triad|*Digestive System Abnormalities|*Syringomyelia|*Anal Canal|*Rectum|*Sacrum|*Genes, Homeobox|*Phenotype|Homeodomain Proteins|Transcription Factors|Mutations|Abnormalities, Multiple|Chinese|Genotype|MNX1 protein, human 159 mnx1 32460659 Zebrafish 2020 10.1089/zeb.2019.1777 0 0 0 116 Animals|*Insulin-Secreting Cells|Zebrafish|Regeneration|Pancreas|Cell Lineage|Cell Proliferation|Animal Models 159 mnx1 32117046 Front Endocrinol (Lausanne) 2020 PMC7010808 10.3389/fendo.2019.00934 0 0 0 116 Humans|Mice|Animals|Phenotypes|*Disease Models, Animal|Ethylnitrosourea|Mutations|Mice, Transgenic|Mutagenesis|Osteochondrodysplasias|Cilia|X-Linked Gene|Gene Expression|Proteins|Knockouts, Gene|Human Genetics 159 mnx1 31924214 Mol. Cancer 2020 PMC6953272 10.1186/s12943-019-1104-1 3 0 0 116 *RNA, Long Noncoding|*Stomach Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Stomach|MicroRNAs|Homeodomain Proteins|Transcription Factors|Cell Line, Tumor|*Neoplastic Processes|Up-Regulation|Disease Progression|Proto-Oncogene Proteins c-bcl-2 159 mnx1 31903751 J. Agric. Food Chem. 2020 10.1021/acs.jafc.9b07151 0 0 0 116 Yarrowia|Metabolic Engineering|Fermentation|Arbutin|Bioreactors 159 MORC1 32493925 Nat Commun 2020 PMC7271234 10.1038/s41467-020-16651-5 0 0 0 59 *Arabidopsis|Mediator Complex|Transcription Factors 26 MORC1 32054438 BMC Evol. Biol. 2020 PMC7020506 10.1186/s12862-019-1575-0 0 0 0 59 Male|Animals|Humans|*Adaptation, Physiological|*Reproduction|Selection, Genetic|Phylogeny|Evolution, Molecular|Testis|Spermatogenesis|*Acclimatization|Primate|Hominidae|Databases, Genetic 26 MPZL2 32203226 Genet. 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Res. 2020 10.1007/s00011-020-01319-z 0 0 0 93 Rats|Mice|Animals|*Compound 48-80|*Mast Cells|*Substance P|*Tachykinin Receptor 1 Antagonists|Cell Degranulation|Receptors, Neuropeptide|Receptors, G-Protein-Coupled|Nerve Tissue Proteins 121 MRGPRX2 31989711 Phytother Res 2020 10.1002/ptr.6615 0 0 0 93 Mice|Animals|piperine|Cell Degranulation|*Polyunsaturated Alkamides|*Benzodioxoles|Mast Cells|*Alkaloids|*Piperidines|Anaphylaxis|Receptors, G-Protein-Coupled|*Signal Transduction|Mice, Inbred C57BL|Mice, Knockout|Cell Line 121 MRGPRX2 31985601 Invest Radiol 2020 10.1097/RLI.0000000000000644 0 0 0 93 Humans|*HLA-DRB1 Chains|*Contrast Media|*Anaphylaxis|*HLA-B|HLA-DQ beta-Chains|Gene Frequency|Alleles|Genetic Predisposition to Disease|Genotype|Case-Control Studies|*Iodine Compounds 121 MRO 32664409 Sensors (Basel) 2020 10.3390/s20143865 0 0 0 123 *Temperature|Biomechanical Phenomena|*Orientation, Spatial|*Dietary Fiber|*Laxatives 186 MRO 32338937 Psychol Assess 2020 10.1037/pas0000826 0 0 0 123 Child|Infant|Humans|Reproducibility of Results|*Interpersonal Relations|Object Attachment|Parenting|Child Development|Emotions|Psychological Tests|*Orientation, Spatial|*Sexual Partners 186 MRO 32305458 Comp. 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U.S.A. 2020 PMC7071853 10.1073/pnas.1909907117 3 0 0 123 Animals|*Myxozoa|*Cnidarian|*Salmon|*Parasites|Phylogeny|Genomes|Evolution, Molecular|*Seafood|Mitochondria 186 MRO 32031713 J Eur Acad Dermatol Venereol 2020 10.1111/jdv.16264 0 0 0 123 *Hidradenitis Suppurativa|*Apocrine Glands|Skin 186 MRO 31992508 Infect Dis Health 2020 10.1016/j.idh.2019.12.006 0 0 0 123 Humans|*Feelings|Nursing Staff, Hospital|Caring|Attitude of Health Personnel|Nursing Methodology Research|Qualitative Research|Surveys and Questionnaires 186 MRO 31953482 Spinal Cord 2020 10.1038/s41393-020-0420-z 0 0 0 123 *Probiotics|Double-Blind Method|Lactobacillus rhamnosus|Vancomycin Resistance|Methicillin-Resistant Staphylococcus aureus|Enterococcus|*Injury, Spinal Cord 186 MSMB 32630458 Biomedicines 2020 10.3390/biomedicines8060173 0 0 0 106 Humans|Male|*Prostate|*Prostate-Specific Antigen|*Hyperplasia|*Prostate Cancer|*Biopsy|Antigens, Neoplasm|Biomarkers, Tumor|ROC Curve|*Immunologic Tests 119 MSMB 32532042 Int J Mol Sci 2020 PMC7312034 10.3390/ijms21114151 0 0 0 106 119 MSMB 32065238 Hum. 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Genet. 2020 10.1093/hmg/ddaa026 0 0 0 106 119 MSMB 31983827 Indian J Urol 2020 PMC6961425 10.4103/iju.IJU_202_19 0 0 0 106 119 MSX1 32648061 Clin Oral Investig 2020 10.1007/s00784-020-03437-8 0 0 0 682 PAX9 Transcription Factor|Anodontia|*Tooth Diseases|Polymorphism, Single Nucleotide 1020 MSX1 32630554 Int J Mol Sci 2020 PMC7350265 10.3390/ijms21124529 0 0 0 682 Humans|Female|*Endometrial Carcinomas|Carcinoma, Endometrioid|Transcription Factors|Prognosis|*Uterus|Tumor Suppressor Protein p53|MSX1 protein, human|MSX1 Transcription Factor 1020 MSX1 32571211 BMC Genomics 2020 PMC7310078 10.1186/s12864-020-06825-2 0 0 0 682 *Mesenchymal Stem Cells|*Transcriptome|Bone Marrow Cells|*Sequencing, RNA|Cell Differentiation|Adipose Tissue|Cells, Cultured|Gene Expression Profiling|Immunophenotyping|*Base Sequence|Cell Proliferation|*Whole Exome Sequencing|RNA 1020 MSX1 32467233 Development 2020 10.1242/dev.189175 0 0 0 682 Humans|Cleft Lip|Cleft Palate|MSX1 Transcription Factor|Palate|Transcription Factors|Polymorphism, Single Nucleotide|Interactions, Gene-Environment 1020 MSX1 32417535 Bone 2020 10.1016/j.bone.2020.115409 0 0 0 682 *Neural Crest|*Cell Differentiation|*Cartilage|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Body Patterning|Osteogenesis|SOX9 protein, human|SOX9 Transcription Factor|Gene Expression Regulation, Developmental|Cell Movement|Skull|Head|Signal Transduction 1020 MSX1 32381388 Br J Oral Maxillofac Surg 2020 10.1016/j.bjoms.2020.04.006 0 0 0 682 Humans|*Tooth, Impacted|*Maxilla|Radiography, Panoramic|Mandible|Tooth Eruption|*Molar|Genes, Homeobox|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|BMP2 protein, human|Bone Morphogenetic Protein 2|Tooth Germ|MSX1 protein, human|MSX1 Transcription Factor 1020 MSX1 32362572 Reprod. Biomed. Online 2020 10.1016/j.rbmo.2019.11.007 0 0 0 682 Humans|Female|*Adenomyoses|*Endometrium|Endometriosis|Epithelial Cells|*Exocrine Glands 1020 MSX1 32322170 Cancer Cell Int. 2020 PMC7161125 10.1186/s12935-020-01191-1 0 0 0 682 *Kinesin|*Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 1020 MSX1 32318854 Hum. Genet. 2020 10.1007/s00439-020-02169-9 1 0 0 682 Humans|Animals|Mice|*Cleft Lip|Cleft Palate|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Regulatory Sequences, Nucleic Acid|Genotype|Alleles|White|Hispanic|Pedigree|Sequencing, Whole Exome|Ethnicity|*Palate|Los Angeles 1020 MSX1 32249341 Prog Orthod 2020 PMC7131971 10.1186/s40510-020-00309-5 0 0 0 682 Anodontia|Malocclusion|Cephalometry|Genotype|Phenotype|Polymorphism, Single Nucleotide|*Tooth Diseases 1020 MSX1 32244388 J Clin Med 2020 PMC7230570 10.3390/jcm9040968 0 0 0 682 Humans|*Mesenchymal Stem Cells|Bone Marrow Cells|*Bone and Bones|Cell Culture Techniques|Cell Differentiation|Cell Proliferation|Cell Count 1020 MSX1 32232327 J. Clin. Endocrinol. Metab. 2020 PMC7185955 10.1210/clinem/dgaa165 1 0 0 682 Humans|Female|*Polycystic Ovary Syndrome|*Electroacupuncture|*Muscle, Skeletal|*Gene Expression|Insulin Resistance|Insulin 1020 MSX1 32192766 Biochem. Biophys. Res. Commun. 2020 10.1016/j.bbrc.2020.03.068 0 0 0 682 Humans|Mice|Animals|MSX1 Transcription Factor|Homeodomain Proteins|Transcription Factors|Anodontia|*Organogenesis|Gene Expression Regulation, Developmental|MSX1 protein, human 1020 MSX1 32191914 Reproduction 2020 PMC7259611 10.1530/REP-19-0402 0 0 0 682 Pregnancy|Female|Mice|Animals|*AMP-Activated Protein Kinases|*Uterus|Implantation, Embryo|Decidua|Pseudopregnancy|Progesterone|Stromal Cell|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Mice, Knockout|Signal Transduction|BMP2 protein, human|INHBB protein, human|Inhibin-beta Subunits|Gene Expression|Transforming Growth Factor beta 1020 MSX1 32090004 J Oral Biol Craniofac Res 2020 PMC7025287 10.1016/j.jobcr.2020.01.002 0 0 0 682 *Signal Transduction|Palates|*Transforming Growth Factor|SMAD2 protein, human|Smad2 Protein|SMAD3 protein, human|Smad3 Protein|Transforming Growth Factor beta|SMAD4 protein, human|Smad4 Protein|Transforming Growth Factor beta3|Organ Cultures|Gene Expression Regulation, Developmental|Cell Proliferation|Phenotype 1020 MSX1 32054232 Asian-australas. 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Sci. 2020 10.5713/ajas.19.0411 0 0 0 682 Pregnancy|Female|Swine|Animals|*Genome-Wide Association Study|*Phenotype|Litter Size|Quantitative Trait Loci|Polymorphism, Single Nucleotide|*Genetic Backgrounds 1020 MSX1 32039004 Front Oncol 2020 PMC6985442 10.3389/fonc.2019.01508 1 0 0 682 1020 MSX1 31922317 Cell Prolif. 2020 PMC7048213 10.1111/cpr.12758 2 0 0 682 Mice|Animals|*Mice, Knockout|NGFR protein, human|*Receptors, Nerve Growth Factor|*Mesenchymal Stem Cells|*Nerve Tissue Proteins|Osteogenesis|Core Binding Factor Alpha 1 Subunit|Cell Differentiation|Integrin-Binding Sialoprotein|Osteocalcin|Calcification, Physiologic|Alkaline Phosphatase|Collagen Type I|Cells, Cultured|Osteopontin 1020 MSX1 31914153 PLoS ONE 2020 PMC6948825 10.1371/journal.pone.0227287 0 0 0 682 Humans|*Anodontia|PAX9 Transcription Factor|MSX1 Transcription Factor|AXIN2 protein, human|Axin Protein|DNA Mutational Analysis|Pedigree|Phenotypes|Mutations|Mutation, Frame Shift|WNT10A protein, human|Wnt Proteins|WNT10B protein, human|Missense Mutation|MSX1 protein, human 1020 MSX1 31909464 Ginekol. Pol. 2020 10.5603/GP.2019.0121 0 0 0 682 Humans|Female|*Carcinoma, Ovarian Epithelial|PAX9 Transcription Factor|*Ovarian Cancer|MSX1 Transcription Factor|Anodontia|AXIN2 protein, human|Axin Protein|Mutation|*Tooth Diseases 1020 MTDH 32552658 Endocr Metab Immune Disord Drug Targets 2020 10.2174/1871530320666200618104116 0 0 0 1112 *Oncogene|*Neoplastic Processes|MicroRNAs|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Cell Adhesion Molecules|Genes, Tumor Suppressor|*Colon Cancer|*Disease Progression|Cell Transformation, Neoplastic|*Colon|Apoptosis 490 MTDH 32503413 J Headache Pain 2020 PMC7275514 10.1186/s10194-020-01125-2 0 0 0 1112 *Migraine with Aura|Genome-Wide Association Study|Migraine|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Phenotype 490 MTDH 32251289 Cell Death Dis 2020 PMC7136213 10.1038/s41419-020-2380-9 0 0 0 1112 Humans|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|*Dinoprostone|*Transcription Factors|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Cell Adhesion Molecules|Cell Line, Tumor|RNA Interference|Up-Regulation|MTDH protein, human 490 MTDH 32207338 Cell Transplant 2020 10.1177/0963689720905506 0 0 0 1112 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Adhesion Molecules|NF-kappa B|Signal Transduction|*Transcription Factors|MTDH protein, human 490 MTDH 32083506 Bioengineered 2020 PMC7039631 10.1080/21655979.2020.1729928 0 0 0 1112 *Neuroblastoma|*Tumorigenesis|Gene Expression Regulation, Neoplastic|MicroRNAs|*Cell Transformation, Neoplastic|Apoptosis|Cell Proliferation|Cell Line, Tumor|Genes, Tumor Suppressor|Gene Knockdown Techniques|Viability, Cell 490 MTDH 32074085 Aging (Albany NY) 2020 PMC7066879 10.18632/aging.102832 2 0 0 1112 Humans|*RNA, Long Noncoding|*Triple-Negative Breast Cancer|Cell Proliferation|*Transcription Factors|MicroRNAs|Neoplasm Invasiveness|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|MTDH protein, human|Cell Adhesion Molecules|FAM83H protein, human|Proteins|MIRN136 microRNA, human 490 MTDH 32066429 BMC Complement Med Ther 2020 PMC7076886 10.1186/s12906-020-2825-9 0 0 0 1112 Humans|Female|Rats|Animals|*Cisplatin|keishibukuryogan|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Drugs, Chinese Herbal|PTEN protein, human|*PTEN Phosphohydrolase|guizhi-fuling|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|Apoptosis|MTDH protein, human|Cell Adhesion Molecules|Pten protein, rat 490 MTDH 32046519 Cell Transplant 2020 10.1177/0963689719897061 0 0 0 1112 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Apoptosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Downregulation|Cell Line, Tumor|3' Untranslated Region|Cell Movement|Signal Transduction|mRNA|Disease Progression|MTDH protein, human|Cell Adhesion Molecules|MIRN497 microRNA, human 490 MTDH 32021458 Cancer Manag Res 2020 PMC6983475 10.2147/CMAR.S246065 0 0 0 1112 *Immunohistochemistry|*RNA-Seq|*Urinary Bladder|*Urinary Bladder Neoplasms|*Whole Exome Sequencing|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|*Carcinoma, Transitional Cell|Cell Adhesion Molecules 490 MTDH 32003433 Biochem. J. 2020 10.1042/BCJ20190922 0 0 0 1112 *Saccharomyces cerevisiae|Ascomycota|Polyketide Synthases|*Pathway, Biosynthetic|arabitol|Sugar Alcohols|Mannitol|mannitol-1-phosphate dehydrogenase|Sugar Alcohol Dehydrogenases|*Secretion|D-arabinitol dehydrogenase|Mannitol Dehydrogenase|Carbohydrate Metabolism|Anti-Bacterial Agents|EST1 protein, S cerevisiae|Telomerase|Saccharomyces cerevisiae Proteins 490 MTDH 31979093 Cancers (Basel) 2020 PMC7072670 10.3390/cancers12020268 1 0 0 1112 Humans|*Triple-Negative Breast Cancer|phenethyl isothiocyanate|*Down-Regulation|*Isothiocyanates|Cancer Stem Cells|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|CD44 protein, human|Hyaluronan Receptors|MTDH protein, human|Cell Adhesion Molecules 490 MTDH 31978894 Aging (Albany NY) 2020 PMC7053596 10.18632/aging.102694 0 0 0 1112 *Carcinoma, Renal Cell|*Epithelial-Mesenchymal Transition|Kidney Neoplasms|*Signal Transduction|*Transcription Factors|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Movement|Cell Proliferation|Cell Line, Tumor|Disease Progression 490 MTDH 31949691 Int J Clin Exp Pathol 2020 PMC6963071 1 0 0 1112 Humans|*Prognosis|*Gallbladder Neoplasms|*Astrocyte|CDH1 protein, human|*E Cadherin|*Antigens, CD|TNM Classification|Lymphatic Metastasis|Biomarkers, Tumor|Kaplan-Meier Estimate|MTDH protein, human|Cell Adhesion Molecules 490 MTDH 31949678 Int J Clin Exp Pathol 2020 PMC6963103 0 0 0 1112 Humans|*Glioma|*Cell Proliferation|miRNA|Gene Expression Regulation, Neoplastic|*Cell Cycle|Cell Movement|Downregulation|Cell Adhesion Molecules|Proto-Oncogene Proteins c-akt|Cell Line, Tumor|Signal Transduction|*Neoplastic Processes|MTDH protein, human 490 MTDH 31912882 Biosci. Rep. 2020 10.1042/BSR20193153 1 0 0 1112 Humans|Male|*Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|*Apoptosis|MicroRNAs|Cell Proliferation|Cell Movement|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|RNA Interference|Cell Line, Tumor|3' Untranslated Regions|Down-Regulation|*Neoplastic Processes|*Prostate Cancer|MTDH protein, human|Cell Adhesion Molecules|MIRN126 microRNA, human 490 MTDH 31901156 Thorac Cancer 2020 PMC6996984 10.1111/1759-7714.13283 1 0 0 1112 *RNA, Long Noncoding|MicroRNAs|Gene Expression Regulation, Neoplastic|*Disease Progression|Cell Proliferation|Cell Line, Tumor|Cell Movement|3' Untranslated Regions|Up-Regulation|Oncogenesis 490 MTX3 32429280 Toxins (Basel) 2020 PMC7290302 10.3390/toxins12050327 0 0 0 133 21 MXD1 32467232 J. Biol. Chem. 2020 10.1074/jbc.RA120.013228 0 0 0 873 Mice|Animals|*RNA, Long Noncoding|Transcription Factor|MXD1 protein, human|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Gene Expression Regulation, Neoplastic|MicroRNAs|Podocytes|Promoter Regions, Genetic|Downregulation|Diabetic Kidney Disease|Cell Proliferation|Transcriptional Activation|Upregulation|Cell Line, Tumor|Repressor Proteins|Response Elements|Glucose|Carbohydrates 172 MXD1 32156728 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7104257 10.1073/pnas.1921786117 2 0 0 873 Humans|*Cell Proliferation|RNA, Long Noncoding|Proto-Oncogene Proteins c-myc|Transcription, Genetic|Promoter Regions, Genetic|Cell Lines|CRISPR|Chromatin Immunoprecipitation|MXD1 protein, human|Repressor Proteins|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors 172 MXD1 32071205 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7060746 10.1073/pnas.1915060117 1 0 0 873 Mice|Animals|*Transcription Factors|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Proto-Oncogene Proteins c-myc|Repressor Proteins|Basic-Leucine Zipper Transcription Factors|Dendritic Cells 172 MXD1 32053209 FEBS Lett. 2020 10.1002/1873-3468.13759 1 0 0 873 Transcription Factor|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Proto-Oncogene Proteins c-myc|Protein Binding|transcription factor UBF|Pol1 Transcription Initiation Complex Proteins|Transcription, Genetic|Basic-Leucine Zipper Transcription Factors|Transcriptional Activation|Repressor Proteins|Promoter Regions, Genetic|Gene Expression Regulation|DNA|Cell Proliferation|Amino Acid Sequence|Upregulation 172 Mxi1 32208677 ACS Synth Biol 2020 10.1021/acssynbio.9b00498 0 0 0 261 182 Mxi1 32159609 Genet. Mol. Biol. 2020 PMC7198032 10.1590/1678-4685-GMB-2018-0362 0 0 0 261 Humans|Male|*Prostate|Androgen Antagonists|Receptors, Androgen|Prostatic Neoplasms, Castration-Resistant|Androgens|PTEN protein, human|PTEN Phosphohydrolase|Gene Expression|Gene Expression Regulation, Neoplastic|Orchiectomy|Disease Progression|Signal Transduction|Cell Line, Tumor|SSRP1 protein, human|DNA-Binding Proteins|High Mobility Group Proteins|Transcriptional Elongation Factors|MXI1 protein, human 182 MXRA5 32620106 BMC Med Genomics 2020 PMC7333416 10.1186/s12920-020-00750-9 0 0 0 21 *Computational Biology|Gene Regulatory Networks|Gene Expression Profiling|*Heart Failure, Left-Sided 23 MXRA5 32392178 Aging (Albany NY) 2020 PMC7244086 10.18632/aging.103175 0 0 0 21 Humans|Male|*Prostatic Hyperplasia|*Prostate|Signal Transduction|Cell Proliferation|Stromal Cells|MAP Kinase Signaling System|MXRA5 protein, human|Proteoglycans 23 MXRA5 32339978 Eur. J. Cancer 2020 10.1016/j.ejca.2020.03.002 0 0 0 21 Humans|*Pleura|Mesothelioma, Malignant|*Mesothelioma|Pleural Neoplasms|*Lung Neoplasms|Prognosis|Treatment Outcome|*Genomics|Mutation 23 MXRA5 32300359 Front Genet 2020 PMC7142269 10.3389/fgene.2020.00302 0 0 0 21 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|MIRN25 microRNA, human|RNA, Micro|Gene Modules|*Lungs|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Expression 23 MXRA5 32230306 Zootaxa 2020 10.11646/zootaxa.4746.1.1 0 0 0 21 Animals|Humans|Phylogeny|Angola|*Lizards|Mitochondria|Biological Evolution|Cell Nucleus|African Continental Ancestry Group|Recognition, Psychology|Research Design 23 MXRA5 31933801 Int J Clin Exp Pathol 2020 PMC6949775 1 0 0 21 Female|Pregnancy|Humans|*Trophoblasts|*Pre-Eclampsia|Cell Line, Tumor|*Placenta|*Apoptosis|MicroRNAs|Cell Movement|Cell Proliferation|Up-Regulation|Viability, Cell|MXRA5 protein, human|Proteoglycans 23 MYCL 32284543 Nat. Cell Biol. 2020 PMC7336275 10.1038/s41556-020-0503-2 0 0 0 170 *Merkel cell polyomavirus|Merkel Cell Carcinoma|Small T-Antigen|Polyomavirus Infections|Tumor Virus Infections|*Cell Transformation, Neoplastic|*Tumorigenesis|Skin Neoplasms|Genes, Tumor Suppressor|Transcription Factor|Chromatin|Cell Line, Tumor|Chromatin Assembly and Disassembly|Histone Demethylases|*Merkel cell polyomavirus|Merkel Cell Carcinoma|Small T-Antigen|Polyomavirus Infections|Tumor Virus Infections|*Cell Transformation, Neoplastic|*Tumorigenesis|Skin Neoplasms|Genes, Tumor Suppressor|Transcription Factor|Chromatin|Cell Line, Tumor|Chromatin Assembly and Disassembly|Histone Demethylases 95 MYCL 32470392 Cancer Cell 2020 10.1016/j.ccell.2020.04.016 0 0 0 170 Humans|Mice|Animals|*Small Cell Lung Carcinoma|*Genes, Tumor Suppressor|Lung Neoplasms|Proto-Oncogene Proteins c-myc|Tumor Suppressor Protein p53|Gene Expression Regulation, Neoplastic|Cell Transformation, Neoplastic|Cell Proliferation|Tumor Cells, Cultured|Inactivation, Gene|Disease Models, Animal 95 MYCL 32071205 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7060746 10.1073/pnas.1915060117 1 0 0 170 Mice|Animals|*Transcription Factors|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Proto-Oncogene Proteins c-myc|Repressor Proteins|Basic-Leucine Zipper Transcription Factors|Dendritic Cells 95 MYCL 32003251 Expert Opin. Ther. Targets 2020 10.1080/14728222.2020.1723548 2 0 0 170 95 MYH15 32670085 Front Physiol 2020 PMC7328665 10.3389/fphys.2020.00633 0 0 0 40 Animals|*Chickens|Pectoral Muscles|*Myopathies|Poultry Diseases|Meat 24 MYH15 32328350 PeerJ 2020 PMC7166044 10.7717/peerj.8950 0 0 0 40 Animals|*Transcriptome|*Chickens|*Pectoral Muscle|Gene Expression Profiling|Sequence Analysis, RNA|Meat|Feathers|Muscle, Skeletal|*Biological Phenomena 24 MYH15 32107856 Int J Rheum Dis 2020 10.1111/1756-185X.13809 0 0 0 40 Humans|*Whole Exome Sequencing|*Polychondritis, Relapsing|Exome|Pedigree|Chinese|Retinitis Pigmentosa|Sequence Analysis, DNA|Mutation 24 MYO15A 32623615 Mol. Biol. Rep. 2020 10.1007/s11033-020-05618-w 0 0 0 19 Humans|*Whole Exome Sequencing|Iran|*Deafness|*Hearing Loss|Recessive Gene|Hearing Loss, Sensorineural|Exome|Connexins|Pedigree|Mutations|Genomics|MYO15A protein, human|Myosins 119 MYO15A 32617096 Neural Plast. 2020 PMC7313121 10.1155/2020/6350479 0 0 0 19 Humans|*Sequencing, Next-Generation|*Mutations|Deafness|Genes, Recessive|Pedigree|Exome|Hearing Loss|Implantation, Cochlear|Asian Continental Ancestry Group|Myosins|Hearing Loss, Sensorineural 119 MYO15A 32451864 Adv. Exp. Med. Biol. 2020 10.1007/978-3-030-38062-5_13 0 0 0 19 Humans|Mice|Animals|*Myosin B|*Hearing|Myosins|Deafness|Hearing Loss|*Hearing Tests|Mutations|Ear, Inner|Dyneins|Myosin VIIa|MYO3A protein, mouse|Myosin Heavy Chains|Myosin Type III 119 MYO15A 32279305 Clin. Genet. 2020 10.1111/cge.13754 0 0 0 19 Humans|Nonsyndromic Deafness|Egypt|Nonsyndromic sensorineural hearing loss|*Hearing Loss, Sensorineural|Deafness|Hearing Loss|Massively Parallel Sequencing|Connexins|Mutations|Genetic Predisposition to Disease 119 MYO15A 32219816 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.04.003 0 0 0 19 Infant, Newborn|Humans|Connexins|Connexin 26|DNA Mutational Analysis|Sulfate Transporters|Deafness|Genetic Testing|RNA, Ribosomal|Neonatal Screening|DNA, Mitochondrial|Mutation|Asian Continental Ancestry Group|Membrane Transport Proteins|China 119 MYO15A 32134349 Acta Otolaryngol. 2020 10.1080/00016489.2020.1730439 0 0 0 19 119 MYO15A 31997689 Fetal Pediatr Pathol 2020 10.1080/15513815.2019.1686790 0 0 0 19 119 MYO15A 31992338 Orphanet J Rare Dis 2020 PMC6986010 10.1186/s13023-020-1311-2 1 0 0 19 Humans|*Molecular Epidemiology|*Alleles|*Mutations|Connexins|Deafness|Connexin 26|*Asian Continental Ancestry Group|Hearing Loss|Heterozygote|Hearing Loss, Sensorineural 119 MYO15A 31902726 Curr. Biol. 2020 PMC7002276 10.1016/j.cub.2019.11.076 2 0 0 19 Mice|Animals|*Stereocilia|*Hair Cells, Auditory, Inner|*Mechanotransduction, Cellular|*Hair Cells, Vestibular|Hair Cells, Auditory|Cilia|Actin|Membrane Proteins 119 MYO15A 31898538 BMC Med. Genet. 2020 PMC6941291 10.1186/s12881-019-0942-4 0 0 0 19 Humans|*Hearing Loss|*Deafness|*Phenotype|Hearing Loss, Sensorineural|Pedigree|Homozygote|Myosins|Asian Continental Ancestry Group|Mutation|*Multifactorial Inheritance|MYO15A protein, human 119 MYO18B 32451870 Adv. Exp. Med. Biol. 2020 10.1007/978-3-030-38062-5_19 0 0 0 35 *Myosin B|Myosins|Actomyosin|Myosin II|Sarcomeres|Actin Cytoskeleton|Muscle Contraction|ATPase|Golgi Apparatus|Cytoskeletal Proteins|Cell Membrane 42 MYO18B 32278351 BMC Musculoskelet Disord 2020 PMC7149842 10.1186/s12891-020-03229-x 0 0 0 35 *Klippel-Feil Syndrome|*Multifactorial Inheritance|Vertebrae|*Mutations|Pedigree 42 MYO18B 32184166 Gene 2020 10.1016/j.gene.2020.144542 1 0 0 35 Male|Humans|Infant, Newborn|Female|Pregnancy|*Muscle Hypotonia|*Phenotypes|Muscular Diseases|Homozygote|Whole Exome Sequencing|*Musculoskeletal Abnormalities|Syndrome|Tumor Suppressor Proteins|Codon, Nonsense|MYO18B protein, human|Myosins 42 myo1f 32272642 Int J Mol Sci 2020 PMC7177449 10.3390/ijms21072555 0 0 0 128 Humans|*Myosin B|Myosins|Actin|Myosin Type I|Amino Acid Sequence|Protein Binding|Plasma Membrane|Protein Domains|Endocytosis|Protein Transport|MYO1F protein, human 25 MYO5C 32477400 Front Genet 2020 PMC7237723 10.3389/fgene.2020.00399 0 0 0 604 Child|Humans|*Homozygote|Heterozygote|Intellectual Disability|Developmental Disabilities|Phenotype|Mutations|Pedigree|Mutation, Missense|GTP-Binding Protein beta Subunits 22 MYOF 32554712 mSphere 2020 PMC7300353 10.1128/mSphere.00313-20 0 0 0 181 *Trypanosoma cruzi|*Myosins|*Cell Membrane|Endocytosis|Microtubules 88 MYOF 32552653 Curr Top Med Chem 2020 10.2174/1568026620666200618123436 0 0 0 181 Membrane Proteins|Muscle Proteins|Calcium-Binding Proteins|Cell Movement|Cell Line, Tumor|Melanoma|Endocytosis 88 MYOF 32487606 Anticancer Res. 2020 10.21873/anticanres.14293 0 0 0 181 Humans|*Clear Cell Renal Cell Carcinoma|Kidney Neoplasms|Neoplasm Invasiveness|Cell Movement|Cell Line, Tumor|Calcium-Binding Proteins|Muscle Proteins|Gene Expression Regulation, Neoplastic|Membrane Proteins|Cell Proliferation|MYOF protein, human 88 MYOF 32348616 Prostate 2020 PMC7291846 10.1002/pros.23983 0 0 0 181 Humans|Male|Animals|Dogs|*Bone Neoplasms|*Prostatic Cancer|Cell Line, Tumor|Neoplasm Transplantation|Osteoblasts|Bone|*B-Lymphocytes|Tumor Microenvironment 88 MYOF 32106631 Cells 2020 PMC7140416 10.3390/cells9030534 0 0 0 181 Animals|Humans|DYSF protein, human|Dysferlin|OTOF protein, human|Membrane Proteins|Muscle Proteins|Muscular Dystrophies|Calcium-Binding Proteins|*Vertebrate|Amino Acid Sequence|Mutations 88 MYOF 31957793 Mol. Biol. Evol. 2020 PMC7182208 10.1093/molbev/msaa005 0 0 0 181 Humans|Genome-Wide Association Study|Japan|*Natural Selection|*Phenotypes|Haplotypes|Quantitative Trait Loci|Genotype|Alleles|Polymorphism, Single Nucleotide|HLA-DPB1 antigen|HLA-DP beta-Chains|*Risk Factors|ADH1B protein, human|Alcohol Dehydrogenase|MYOF protein, human|Calcium-Binding Proteins|Membrane Proteins|Muscle Proteins 88 MYOF 31926587 Discov Med 2020 0 0 0 181 Humans|*Transcriptome|Phosphatidylinositol 3-Kinases|Neoplasm Recurrence, Local|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Cancer|Protein Interaction Maps|Gene Ontology|Gene Expression Profiling|Gene Regulatory Networks|Oligonucleotide Array Sequence Analysis|Computational Biology|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Software|Survival Analysis|Upregulation 88 MYOF 31912559 FASEB J. 2020 10.1096/fj.201901539RR 0 0 0 181 Mice|Animals|*Adiposity|*Obesity|Insulin Resistance|Diet, High-Fat|Adipogenesis|Adipocytes|Adipose Tissue, White|Adipose Tissue, Brown|Body Weight|Fatty Liver|Visceral Fat|Inflammation|Insulin|Energy Metabolism|Mice, Knockout|Cell Differentiation|Glucose 88 Myrf 32651235 Gut 2020 10.1136/gutjnl-2019-319706 0 0 0 290 *Whole Exome Sequencing|*Microbiota|Microbiome, Gut|Inflammatory Bowel Diseases|Genetic Predisposition to Disease|Genome-Wide Association Study|*Epistasis, Genetic 62 Myrf 32602617 J. 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Physiol. 2020 10.1002/jcp.29910 0 0 0 290 *Oligodendrocyte Precursor Cells|*Myelin Sheath|*Cell Differentiation|Oligodendroglia|MicroRNAs|Stem Cells|Transcription Factors|Cells, Cultured|Neurogenesis 62 Myrf 32601750 Brain Struct Funct 2020 10.1007/s00429-020-02108-4 0 0 0 290 Animals|Mice|*Contactin 2|Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Oligodendrocytes|Brain|C57BL Mouse|Contactin 1|Neurogenesis|Transcriptome|In Situ Hybridization|Ncam2 protein, mouse|Neural Cell Adhesion Molecules 62 Myrf 32270922 EMBO Rep. 2020 10.15252/embr.201949783 0 0 0 290 Animals|Mice|*Huntington Disease|*Phosphorylation|Oligodendrocytes|HTT protein, human|Huntingtin Protein|Myelin|PRKG2 protein, human|*Cyclic GMP-Dependent Protein Kinase Type II|Transcription Factor|Demyelinating Diseases|Gene Expression Regulation|Multiple Sclerosis 62 Myrf 32236127 PLoS Genet. 2020 PMC7153906 10.1371/journal.pgen.1008583 0 0 0 290 Humans|Mice|Animals|*Microphthalmos|*Eyes|Transcription Factor|Membrane Proteins|Endoplasmic Reticulum|Hyperopia|Mutations|Gene Expression Regulation|Pedigree|Glaucoma, Angle-Closure|Gene Expression|TMEM98 protein, human 62 Myrf 32052405 Clin. Genet. 2020 10.1111/cge.13722 0 0 0 290 Humans|*Microphthalmos|Australia|Hyperopia, High|Hyperopia|Mutations|Pedigree|Eye Diseases, Hereditary|Eyes|Refractive Error|Membrane Proteins|Serine Proteases|*Cohort Studies|Glaucoma, Angle-Closure|Phenotypes|Haplotypes 62 Myrf 31991592 Nutrients 2020 PMC7071282 10.3390/nu12020310 0 0 0 290 Male|Female|*Genome-Wide Association Study|*Metabolic Syndrome|*Fatty Acids, Omega-6|*Fatty Acids, Omega-3|*Diet|Fatty Acid Desaturases|Polyunsaturated Fatty Acids|Polymorphism, Single Nucleotide|Genotype|Multigene Family 62 Myrf 31964908 Sci Rep 2020 PMC6972908 10.1038/s41598-020-57593-8 0 0 0 290 Transcription Factor|*Mutations|Protein Binding|Membrane Proteins|Oligodendroglia|Haploinsufficiency|Amino Acid Sequence|Cell Nucleus|Whole Exome Sequencing|Gene Expression Regulation|Models, Molecular 62 MZB1 32377723 Int. J. Oncol. 2020 10.3892/ijo.2020.5056 0 0 0 35 *Proteomics|*Multiple Myeloma|*B-Lymphocyte Subsets|*Biomarkers|Proteome|Bioinformatics|Gene Expression Profiling|Cytokines|Downregulation|Upregulation|*Lymphoid Tissue|Plasma 25 MZB1 32304408 Anticancer Drugs 2020 10.1097/CAD.0000000000000926 0 0 0 35 Humans|Male|Female|*Carcinoma, Non-Small-Cell Lung|*RNA, Micro|*Lung Cancer|rhodioloside|*Glucosides|*Phenols|Cell Lines, A549|Neoplasm Invasiveness|3' Untranslated Region|Downregulation|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MIRN103 microRNA, human 25 MZB1 32079689 Haematologica 2020 10.3324/haematol.2019.235424 0 0 0 35 Humans|*Multiple Myeloma|*RNA Splicing|RNA Splicing Factors|Ribonucleoprotein, U2 Small Nuclear|Alternative Splicing|Spliceosome|Mutations|Myelodysplastic Syndromes|Phosphoproteins|RNA|DHX9 protein, human|Neoplasm Proteins|DEAD-box RNA Helicases 25 MZB1 32000799 J Transl Med 2020 PMC6993458 10.1186/s12967-020-02220-3 0 0 0 35 Humans|*Crohn Disease|*Mesentery|*Biomarkers|*Signal Transduction|*Adipose Tissue|Intestinal Mucosa|Intestines|Case-Control Studies|*Plasma 25 MZB1 31901757 Bioorg. Chem. 2020 10.1016/j.bioorg.2019.103457 0 0 0 35 *Rectum|*Apoptosis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Gene Regulatory Networks|Cell Line, Tumor|*Correlation of Data|Adenocarcinoma 25 MZF1 32602796 Immunol. Invest. 2020 10.1080/08820139.2020.1778023 0 0 0 334 Humans|Female|*Uterine Cervical Neoplasms|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|HPV Infection|Asian Continental Ancestry Group|Interleukin-17|Case-Control Studies|Risk Factors|Precancerous Conditions 165 MZF1 32449233 J. Oral Pathol. Med. 2020 10.1111/jop.13038 0 0 0 334 *Transcription Factor|*Polymorphism, Single Nucleotide|*Vascular Endothelial Growth Factor A|*Promoter Regions, Genetic|Kruppel-Like Transcription Factors|*Smoke|*Tobacco|*Vascular Endothelial Growth Factors|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Carcinogenesis|Smoking 165 MZF1 32135233 Neuroscience 2020 10.1016/j.neuroscience.2020.02.041 1 0 0 334 Rats|Animals|*Ganglia, Spinal|*Freund's Adjuvant|*Matrix Metalloproteinase 2|*Up-Regulation|*Potassium|Hyperalgesia, Thermal|Pain, Neuropathic|*Transcriptional Activation|Pain Threshold|Rats, Sprague-Dawley|Neurons|Transcription Factors|Zinc Finger 165 MZF1 32042322 Theranostics 2020 PMC6993229 10.7150/thno.37383 1 0 0 334 Mice|Animals|*Glycolysis|*Neuroblastoma|*Disease Progression|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Kruppel-Like Transcription Factors|Mice, Nude|*Citric Acid Cycle|Cell Proliferation|Tumorigenesis|Promoter Regions, Genetic|Yy1 protein, mouse|YY1 Transcription Factor 165 MZF1 31963147 Cells 2020 PMC7016646 10.3390/cells9010223 0 0 0 334 Humans|*Transcription Factor|Epithelial-Mesenchymal Transition|Kruppel-Like Transcription Factors|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Cell Line, Tumor|Oncogenes|Zinc Fingers|MZF1 protein, human 165 MZF1 31948960 Microbiol Resour Announc 2020 PMC6965578 10.1128/MRA.01348-19 0 0 0 334 *Enterococcus faecium|*Probiotics|*Meat|Anti-Bacterial Agents 165 nanos2 32484162 Reproduction 2020 10.1530/REP-20-0095 0 0 0 136 Male|Humans|activin A|*Activin|inhibin beta A subunit|*Inhibin-beta Subunits|*Germ Line|*Cell Differentiation|Testicular Germ Cell Tumor|Testicular Neoplasms|Neoplasms, Germ Cell and Embryonal|Testis|Seminoma|Nodal Protein|Transforming Growth Factor beta|Signal Transduction|BMP4 protein, human|Bone Morphogenetic Protein 4 118 nanos2 32423131 Animals (Basel) 2020 PMC7278407 10.3390/ani10050851 0 0 0 136 Male|Spermatogonia|Spermatogenesis|Testis|Stem Cells 118 nanos2 32344590 Int J Mol Sci 2020 PMC7215683 10.3390/ijms21083009 0 0 0 136 Male|Humans|Mice|Animals|*Germ-Line Cell|Seminiferous Tubules|RNA-Binding Proteins|mRNA|*Apoptosis|Amino Acid Sequence|*Gene Expression|Mutation|Genes, Regulator|Cell Line|NANOS3 protein, human 118 nanos2 32339196 PLoS ONE 2020 PMC7185693 10.1371/journal.pone.0232047 0 0 0 136 Humans|Male|Mice|Animals|*Incidence|Teratoma, Testicular|*Teratoma|*Testicular Neoplasms|Embryonic Germ Cells|Spermatogonia|Testis|Spermatogenesis|Neoplasm Proteins|Cell Differentiation|Knockout Mouse|NANOS3 protein, human|RNA-Binding Proteins|Nanos2 protein, mouse|Dnd1 protein, mouse 118 nanos2 31954748 Gen. Comp. Endocrinol. 2020 10.1016/j.ygcen.2019.113341 0 0 0 136 Male|Animals|*Spermatogonia|Testes|Stem Cells|Cultured Cells|Feeder Layer|Cell Differentiation|Rainbow Trout|Co-culture|Biomarkers 118 nanos2 31940692 J. Vet. Sci. 2020 PMC7000897 10.4142/jvs.2020.21.e13 0 0 0 136 Male|Animals|*Buffaloes|Spermatogonia|Adult Germline Stem Cells|Spermatogenesis|Cells, Cultured|Testis|Cell Culture Techniques|Adult Stem Cells|*Bison 118 NCAM2 32601750 Brain Struct Funct 2020 10.1007/s00429-020-02108-4 0 0 0 77 Animals|Mice|*Contactin 2|Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Oligodendrocytes|Brain|C57BL Mouse|Contactin 1|Neurogenesis|Transcriptome|In Situ Hybridization|Ncam2 protein, mouse|Neural Cell Adhesion Molecules 71 NCAM2 32043120 Cereb. Cortex 2020 PMC7233011 10.1093/cercor/bhz342 0 0 0 77 *Cytoskeletal Proteins|Proteomics|*Axons|NCAM2 protein, human|*Neural Cell Adhesion Molecule L1|Neurons|Neurites|Microtubule-Associated Proteins|Hippocampus|Autism|Microtubules|Brain|Down Syndrome|*Cell Differentiation 71 NCOA4 32661669 Head Neck Pathol 2020 10.1007/s12105-020-01198-0 0 0 0 263 *Carcinoma, Intraductal, Noninfiltrating|Salivary Gland Neoplasms|*Lymph Node|Biomarkers, Tumor|S100 Proteins|Phenotype|Receptor Protein-Tyrosine Kinases 211 NCOA4 32659785 Blood 2020 10.1182/blood.2020006321 0 0 0 263 Humans|Mice|Animals|*Iron|*Iron, Dietary|Ferritin|Nuclear Receptor Coactivators|*Transcription Factors|Erythropoiesis|Anemia|*Liver|Autophagy|Homeostasis|Cell Lines|NCOA4 protein, human|NcoA4 protein, mouse 211 NCOA4 32608971 Biochemistry 2020 10.1021/acs.biochem.0c00246 0 0 0 263 Humans|*Ferritin|*Kinetics|Iron|Lysosomes|Nuclear Receptor Coactivators|Phagosomes|Autophagy|Homeostasis|*Transcription Factors|*Thermodynamic|NCOA4 protein, human 211 NCOA4 32606852 Diabetes Metab Syndr Obes 2020 PMC7294720 10.2147/DMSO.S249382 0 0 0 263 *Ferroptosis|*Diabetes Mellitus|Cell Death|Glutathione Peroxidase|Hypoglycemic Agents|Cell Line, Tumor|Reactive Oxygen Species|Lipid Peroxidation|Mulberry|Iron|Glutathione 211 NCOA4 32283200 Food Chem. Toxicol. 2020 10.1016/j.fct.2020.111329 0 0 0 263 Male|Mice|Animals|*Diet, High-Fat|*Insulin Resistance|*Endoplasmic Reticulum Stress|Glycogen Synthase Kinase 3|*Liver|Non-alcoholic Fatty Liver Disease|HepG2 Cells|Inflammation|NcoA4 protein, mouse|Nuclear Receptor Coactivators 211 NCOA4 32256964 Oxid Med Cell Longev 2020 PMC7091554 10.1155/2020/9762390 0 0 0 263 *Epithelial-Mesenchymal Transition|*Reactive Oxygen Species|*Tumor Suppressor Protein p53|di-n-propyldithiocarbamate|*Ditiocarb|Ferritin|Lysosomes|Cell Line, Tumor|HepG2 Cell 211 NCOA4 32186434 Autophagy 2020 10.1080/15548627.2020.1739447 1 0 0 263 Humans|Animals|*DNA, Mitochondrial|Autophagy|Cell Death|*Mitochondria|Apoptosis|Lipid Peroxidation|Reactive Oxygen Species|*Death, Autophagy-Dependent Cell|Signal Transduction|Pancreatic Cancer|Iron 211 NCOA4 32162306 J. 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Mutat. 2020 10.1002/humu.24059 0 0 0 382 Humans|DNA Copy Number Variations|*Data Analysis|*Colorectal Cancer|*Mutations|Prognosis|Carcinogenesis|SMAD4 protein, human|Smad4 Protein|*Colonic Neoplasms|IRF5 protein, human|Interferon Regulatory Factors|DNA Methylation|PMEPA1 protein, human|Membrane Proteins 89 NEFH 32474563 Eur. Neurol. 2020 10.1159/000507854 0 0 0 382 methylthio-ADP|*Injury, Spinal Cord|Thionucleotides|*Receptors, Purinergic P2Y|Adenosine Diphosphate|Purinergic P2 Receptor Antagonists|Spinal Cord|Recovery of Function|Purinergic Agonists 89 NEFH 32166880 Eur. J. Neurol. 2020 10.1111/ene.14213 0 0 0 382 Humans|*Amyotrophic Lateral Sclerosis|RNA-Binding Protein FUS|Superoxide Dismutase-1|Genetic Association Studies|Mutations|Phenotype|Superoxide Dismutase|Genetic Predisposition to Disease|DNA-Binding Proteins|*Chromosome Structures|China 89 NEFH 32028016 Food Chem. 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Toxicol. 2020 10.1007/s00204-019-02635-y 0 0 0 382 Animals|Mice|*Flame Retardants|*Microglia|*Inflammation Mediators|*Mice, Inbred C57BL|Organophosphates|Organophosphorus Compounds|*Neurotoxicity Syndromes|Zebrafish|mRNA|Phosphate|Cell Survival|Neurons|Hippocampus|Inflammation 89 NEIL3 32598485 FEBS Lett. 2020 10.1002/1873-3468.13876 0 0 0 86 *DNA Glycosylase|*DNA Repair|DNA-Formamidopyrimidine Glycosylase|FLJ10858 protein, human|Escherichia coli Proteins|Guanine|DNA|Substrate Specificity|Mutations|Oxidative Stress|*Biochemical Phenomena 87 NEIL3 32364878 Tumour Biol. 2020 10.1177/1010428320918404 0 0 0 86 Base Excision Repair|DNA Glycosylases|DNA Damage|DNA 87 NEIL3 32300177 Oncogene 2020 PMC7239769 10.1038/s41388-020-1280-x 0 0 0 86 Humans|Male|*African Americans|*European Continental Ancestry Group|Genes, BRCA2|*Prostate Cancers|BRCA2 protein, human|BRCA2 Protein|Mutation|*DNA|Carcinogenesis|ERCC6 protein, human|Poly-ADP-Ribose Binding Proteins|DNA Helicases|DNA Repair Enzymes 87 NEIL3 32175161 Turk Gogus Kalp Damar Cerrahisi Derg 2020 PMC7067012 10.5606/tgkdc.dergisi.2020.17279 0 0 0 86 Mesothelioma, Malignant|*Mesothelioma|*Lung Adenocarcinoma|*Lung Neoplasms|Pleural Neoplasms|Pleural Effusion, Malignant|Adenocarcinoma|Biomarkers, Tumor|Prognosis|Diagnosis, Differential|*Gene Expression 87 NEIL3 32033115 Cancers (Basel) 2020 PMC7072512 10.3390/cancers12020349 0 0 0 86 DNA Helicases|Transcription Factors|Nuclear Proteins|Chromatin Assembly and Disassembly|*Cell Cycle Genes|Promoter Regions, Genetic|Cell Line, Tumor|Cell Cycle|Cell Proliferation 87 NEIL3 31981739 DNA Repair (Amst.) 2020 10.1016/j.dnarep.2020.102804 0 0 0 86 Humans|*DNA, Single-Stranded|*B-DNA|Replication Protein A|DNA Repair|DNA Replication|Single Stranded DNA Binding Proteins|DNA Damage|Rad51 Recombinase|DNA|Recombination, Genetic|Protein Binding|Saccharomyces cerevisiae|ALKBH3 protein, human|AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase 87 NEIL3 31980815 Nucleic Acids Res. 2020 PMC7102959 10.1093/nar/gkaa038 2 0 0 86 Humans|*Fanconi Anemia|*Base Excision Repair|Fanconi Anemia Complementation Group D2 Protein|FLJ10858 protein, human|DNA Breaks, Double-Stranded|DNA Replication|DNA Damage|Psoralen|DNA Glycosylase|DNA|Ubiquitin-Protein Ligases|RUVBL1 protein, human|ATPases Associated with Diverse Cellular Activities|Carrier Proteins|DNA Helicases|TRAIP protein, human 87 NEIL3 31945542 DNA Repair (Amst.) 2020 PMC7065521 10.1016/j.dnarep.2019.102773 3 0 0 86 Animals|*B-DNA|*Lyases|*DNA Repair|Pol beta protein, human|DNA Polymerase beta|APEX1 protein, human|AP Lyase|*DNA|oxoguanine glycosylase 1, human|DNA Glycosylases|DNA Damage|TYRP1 protein, human|*Oxidation-Reduction|*Membrane Glycoproteins|DNA-Directed DNA Polymerase|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|5'-deoxyribose-5-phosphate 87 NEIL3 31930277 Genet. 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Genet. 2020 10.1038/s10038-020-0795-x 0 0 0 171 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Oncogenes|MicroRNAs|*Oncogenesis|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Downregulation|Cell Movement|Sequencing, RNA|Cell Proliferation|Gene Expression Profiling|Cell Line, Tumor|Biomarkers, Tumor|Gene Knockdown Techniques|Cell Transformation, Neoplastic|*Base Sequence 53 NETO2 32488524 Ann Intensive Care 2020 PMC7266115 10.1186/s13613-020-00687-3 0 0 0 171 *Tidal Volume|*Checklist|Respiration, Artificial|Respiratory Distress Syndrome, Adult|Intensive Care Units|*Lung|Hospital Mortality|*Respiration|3'-(1-butylphosphoryl)adenosine|*Ventilation|*Data Management 53 Neurod2 31989157 Cereb. Cortex 2020 PMC7232988 10.1093/cercor/bhz341 0 0 0 154 Humans|HTR1A protein, human|*Receptor, Serotonin, 5-HT1A|Tomography, X-Ray Computed|*Brain|Positron Emission Tomography|N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide|Piperazines|Pyridines|Radiopharmaceuticals|*Anatomy, Regional 116 NEUROD4 32634160 PLoS ONE 2020 10.1371/journal.pone.0235617 0 0 0 53 Female|Animals|*Carp|*Anguilla|*Salmon|*Oogenesis|*Embryonic Developments|*Pituitary Gland|mRNA, Maternal|*Pituitary Diseases|Zygotes|Embryo, Nonmammalian|mRNA|Gene Expression Regulation, Developmental|Vitellogenesis|*Seafood|*Eggs|Plant Extracts 59 NEUROD4 32468054 Mol Med Rep 2020 PMC7339802 10.3892/mmr.2020.11174 0 0 0 53 Rats|Animals|*PC12 Cells|Brain Ischemia|Acute Stroke|CASP3 protein, human|Caspase 3|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Apoptosis|bcl-2-Associated X Protein|*Reperfusion|RNA, Micro|Cell Hypoxia|Signal Transduction|Reperfusion Injury|Neurons|Inflammation|Glucose|*Cell Communication 59 NEUROD4 32192535 Neural Dev 2020 PMC7082998 10.1186/s13064-020-00142-w 0 0 0 53 *Retina|*Progenitor Cells|Photoreceptors, Cone|Cell Differentiation|Retinal Ganglion Cells|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Homeodomain Proteins|Transcription Factors|Embryo, Mammalian 59 NEUROD6 32609332 Cereb. Cortex 2020 10.1093/cercor/bhaa171 0 0 0 73 Humans|Pregnancy|Female|Animals|Sheep|Diffusion Tensor Imaging|*Plate, Cortical|*Fetus|Brain Mapping|Image Processing, Computer-Assisted|Magnetic Resonance Imaging|Gestational Age|*Prenatal Care|Neurite 84 NEUROD6 32474563 Eur. Neurol. 2020 10.1159/000507854 0 0 0 73 methylthio-ADP|*Injury, Spinal Cord|Thionucleotides|*Receptors, Purinergic P2Y|Adenosine Diphosphate|Purinergic P2 Receptor Antagonists|Spinal Cord|Recovery of Function|Purinergic Agonists 84 NEUROD6 32404936 Nat Commun 2020 PMC7220953 10.1038/s41467-020-16167-y 0 0 0 73 Humans|Child|Mice|Animals|Familial ependymoma|*Ependymoma|LATS1 protein, human|Protein-Serine-Threonine Kinases|LATS2 protein, human|Phosphoproteins|Tumor Suppressor Proteins|Transcription Factors|Adaptor Proteins, Signal Transducing|Nuclear Proteins|Cell Cycle Proteins|Supratentorial Neoplasms|Genes, Regulator|Signal Transduction|Neurod6 protein, mouse|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 84 NEUROG2 32599975 Cancer Res Treat 2020 10.4143/crt.2020.140 0 0 0 512 Child|Humans|*Genome-Wide Association Study|Republic of Korea|*Neuroblastoma|N-Myc Proto-Oncogene Protein|Predispositions, Genetic|Polymorphism, Single Nucleotide|Nuclear Proteins|Genotype|Gene Expression Regulation, Neoplastic|European Continental Ancestry Group|Cell Line, Tumor 330 NEUROG2 32507252 Anim. 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Genet. 2020 10.1016/j.ajhg.2020.06.010 0 0 0 790 Humans|Male|Mice|Animals|Azoospermia, Nonobstructive|Azoospermia|*Infertility, Male|*Alleles|*Mutations|Oligospermia|Homozygote|Meiosis|Spermatogenesis|Sequencing, Whole Exome|Testis|Spermatozoa|Frameshift Mutation|Phenotype|Turkey 145965 NHS 32673417 Cancer 2020 10.1002/cncr.33033 0 0 0 790 Humans|*Carcinoma, Renal Cell|*Nivolumab|*Everolimus|*Follow-Up Studies|Kidney Neoplasms|Antibodies, Monoclonal|Antineoplastic Combined Chemotherapy Protocols 145965 NHS 32673122 Expert Rev Anti Infect Ther 2020 10.1080/14787210.2020.1792289 0 0 0 790 Humans|*Coronavirus|COVID-19|*Pandemics|*Smell|severe acute respiratory syndrome coronavirus 2|*Taste|Pneumonia, Viral|*Coronavirus Infections|Betacoronavirus|Olfaction Disorders|Taste Disorders|Severe Acute Respiratory Syndrome|*Biomarkers|Brazil|France|Italy|Spain 145965 NHS 32672598 Ophthalmol Glaucoma 2020 10.1016/j.ogla.2019.12.007 0 0 0 790 Intraocular Pressure|Trabeculectomy|Glaucoma|*Hydrophthalmos|Visual Acuity|Tonometry, Ocular 145965 NHS 32672477 Eur J Cardiovasc Nurs 2020 10.1177/1474515120939007 0 0 0 790 Humans|Qualitative Research 145965 NHS 32672436 J Cardiovasc Surg (Torino) 2020 10.23736/S0021-9509.20.11377-6 0 0 0 790 Humans|*Aortic Aneurysm, Abdominal|*Elective Surgical Procedures|Endovascular Procedures|Blood Vessel Prosthesis Implantation|Retrospective Studies|Risk Factors|Hospital Mortality|Treatment Outcome|Sex Factors|Quality Improvement 145965 NHS 32672399 Health Info Libr J 2020 10.1111/hir.12322 0 0 0 790 Humans|severe acute respiratory syndrome coronavirus 2|COVID-19|*Health Literacy|Betacoronavirus|Coronavirus Infections|Pandemic|Pneumonia, Viral|Coronavirus|Public Health|Global Health|World Health Organization|Emergency|Government|Emergency Service, Hospital 145965 NHS 32672365 Cochrane Database Syst Rev 2020 10.1002/14651858.CD001304.pub3 0 0 0 790 *Phenylketonuria|Phenylalanine|Dietary Supplements|Amino Acids|Learning Disability|Relaxation|Psychiatry 145965 NHS 32672336 Age Ageing 2020 10.1093/ageing/afaa142 0 0 0 790 Humans|Female|*Quality Improvement|*Parkinson Disease|Neurodegenerative Diseases|*Parkinsonian Disorders|Hospitals|Hospitalization|*Pharmaceutical Preparations 145965 NHS 32672324 Photochem. 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Sci. 2020 10.1039/d0pp00188k 0 0 0 790 Humans|Ultraviolet Rays|*Microfibrils|*Ethnic Groups|*Skin|Fibrillins|Skin Aging|Dermis|Elastic Tissue|Epidermis|Fibrillin-1|Extracellular Matrix Proteins|Extracellular Matrix|Fibronectins|Microfilament Proteins|Atomic Force Microscopy|*Phototherapy 145965 NHS 32672066 Foot Ankle Int 2020 10.1177/1071100720937645 0 0 0 790 *Hallux Valgus|*Flatfoot|*Osteotomy|Metatarsal Bones|*Bunion|Radiography|*Recurrence|Retrospective Studies|Treatment Outcome|*Talipes 145965 NHS 32671996 Cancer Rep (Hoboken) 2020 10.1002/cnr2.1230 0 0 0 790 Male|Humans|*Feasibility Studies|*Watchful Waiting|*Prostate Cancer|*Delivery of Health Care|Quality of Life|Cost-Benefit Analysis 145965 NHS 32671950 HIV Med. 2020 10.1111/hiv.12879 0 0 0 790 United Kingdom|*HIV Infections|*Drug Interactions|*Polypharmacy|Antiretroviral Therapy, Highly Active|Anti-Retroviral Agents|Anti-HIV Agents|Comorbidity|Age Factors|Risk Factors|*Databases, Factual 145965 NHS 32671929 Health Expect 2020 10.1111/hex.13103 0 0 0 790 Child|Female|Pregnancy|Humans|*Mothers|*Hypoplastic Left Heart Syndrome|*Qualitative Research|Diagnosis, Antenatal|Decision Making|Counseling 145965 NHS 32671884 Scand J Med Sci Sports 2020 10.1111/sms.13772 0 0 0 790 *Soccer|*Walking|Football 145965 NINJ1 32385864 FASEB J. 2020 10.1096/fj.201902753R 0 0 0 93 Mice|Animals|*Colitis|*Macrophage Activation|*Macrophages|Inflammatory Bowel Disease|Dextran Sulfate|Colon|Cytokines|Homeostasis|Disease Models, Animal|Cell Differentiation|Ninj1 protein, mouse|Nerve Growth Factors|Cell Adhesion Molecules, Neuronal 71 NINJ1 32353975 Cells 2020 PMC7291157 10.3390/cells9051086 0 0 0 93 Humans|*Monocytes|Human Umbilical Vein Endothelial Cells|Nerve Growth Factors|Cell Adhesion Molecules, Neuronal|Cell Adhesion|Cells, Cultured|Endothelium|siRNA|Leukocytes|Neutrophils|Up-Regulation|*Tumors|NINJ1 protein, human 71 NINJ1 32325790 Nutrients 2020 PMC7230898 10.3390/nu12041140 1 0 0 93 *Vitamin D|*Vitamins|Receptors, Calcitriol|Monocytes|Gene Expression Regulation|Chromatin|*Cholestanes 71 NINJ1 32147432 Life Sci. 2020 10.1016/j.lfs.2020.117518 0 0 0 93 Humans|*Monocytes|*Amlodipine|*Endothelial Cells|*Upregulation|Vascular Cell Adhesion Molecule-1|Reactive Oxygen Species|NADPH Oxidases|NF-kappa B|Endoplasmic Reticulum Stress|Oxidative Stress|Cell Adhesion|*Transcriptional Activation|p38 Mitogen-Activated Protein Kinases|Tumor Necrosis Factor-alpha|Cells, Cultured|Receptors, Tumor Necrosis Factor 71 NINJ1 31963519 Int J Mol Sci 2020 PMC7013940 10.3390/ijms21020614 0 0 0 93 Animals|Mice|*Myeloid Cells|Cell Adhesion|Nerve Growth Factors|Cell Adhesion Molecules, Neuronal|Endothelial Cells|Cell Migration|*Synapsins|Signal Transduction|Cells, Cultured|Macrophages|*Intestines|*Intestinal Diseases|Inflammation|Ninj1 protein, mouse 71 NLRP5 32613414 J. Assist. Reprod. Genet. 2020 10.1007/s10815-020-01871-x 0 0 0 64 Female|Sheep|Animals|*Oocyte|Embryogenesis|Blastocyst|Zygote|Gene Expression Regulation, Developmental|Transcription Factors|Cytoplasm|Maternal Age 65 NLRP5 32326631 Animals (Basel) 2020 PMC7222816 10.3390/ani10040689 0 0 0 64 Female|Pregnancy|Sheep|Animals|Litter Size|Genotype|Breeding|Polymorphism, Single-Stranded Conformational|Gene Frequency|*Mutations|Reproduction|Polymorphism, Single Nucleotide|Polymerase Chain Reaction 65 NLRP5 32222962 Clin. Genet. 2020 10.1111/cge.13744 0 0 0 64 Pregnancy|Female|Humans|*Homozygote|*Embryo, Mammalian|Embryonic Development|Oocytes|Infertility, Female|Ovary|Mutation 65 NLRP5 32172300 Hum. Genet. 2020 10.1007/s00439-020-02143-5 0 0 0 64 Pregnancy|Humans|Female|Infertility, Female|*Abortion, Habitual|Sequencing, Whole Exome|Fertilization in Vitro|*Genomics|Fertility|Genetic Predisposition to Disease|Reproduction|Mutation|Cohort Studies|Tle6 protein, human|Transcription Factors|CENPH protein, human|Chromosomal Proteins, Non-Histone 65 NNAT 32628919 Brain Res. 2020 10.1016/j.brainres.2020.147006 0 0 0 165 Animals|Male|Rats|*Solitary Nucleus|*Bombesin|*Rats, Sprague-Dawley|cholecystokinin 8|*Cholecystokinin|*Neurons|Paraventricular Hypothalamic Nucleus|Proto-Oncogene Proteins c-fos|Sincalide|Peptide Fragments 168 NNAT 32499872 Oncotarget 2020 PMC7244018 10.18632/oncotarget.27583 0 0 0 165 Humans|CpG Islands|*Epigenesis, Genetic|DNA Methylation|Genomic Imprinting|Nerve Tissue Proteins|Membrane Proteins|*Osteosarcoma|Bone Neoplasms 168 NNAT 31997824 Neural Regen Res 2020 PMC7059563 10.4103/1673-5374.274348 0 0 0 165 Animals|Rats|*Long Non-Coding RNA|*Transcriptome|*Rats, Sprague-Dawley|*Transcriptome Analysis|Sequencing, RNA|*Injury, Spinal Cord|RNA, Messenger|Gene Expression Regulation|Gene Ontology|Disease Models, Animal 168 NOBOX 32409601 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7275758 10.1073/pnas.1918556117 0 0 0 47 Male|Animals|Germ Cells|Oogenesis|Sex Determination Processes|Gonads|Oryzias|Sperm|Vertebrates|Forkhead Transcription Factors 103 NOBOX 32086523 Nucleic Acids Res. 2020 PMC7144910 10.1093/nar/gkaa101 0 0 0 47 Female|Mice|Animals|*Transcription Factor|*Oogenesis|Oocyte|*Cell Differentiation|LIM-Homeodomain Proteins|Ovarian Follicle|Meiosis|Germ Cells|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|*Cell Proliferation|Gene Expression Regulation, Developmental|Ovaries|Figla protein, mouse|Ybx2 protein, mouse|RNA-Binding Proteins 103 NOBOX 31900800 In Vitro Cell. Dev. Biol. Anim. 2020 10.1007/s11626-019-00411-x 0 0 0 47 Female|Mice|Animals|*Ovary|*Cell Differentiation|*Stem Cells|Oogonial Stem Cells|Oocytes|Germ Cell|BMP4 protein, human|Bone Morphogenetic Protein 4|GDF9 protein, human|GDF-9|Retinoic Acid|Granulosa Cell|Mesenchymal Stem Cells 103 nos1ap 32436959 Hum. Mol. Genet. 2020 10.1093/hmg/ddaa098 0 0 0 240 Genome-Wide Association Study|*Blood Pressure|*Regulatory Regions|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Chromatin|Phenotype|Genetic Variation|*Blood Pressure Determination 183 nos1ap 32429735 Circulation 2020 10.1161/CIRCULATIONAHA.120.045956 0 0 0 240 183 nos1ap 32321746 J. Neurosci. 2020 PMC7204083 10.1523/JNEUROSCI.0046-20.2020 0 0 0 240 Male|Female|Rats|Mice|Animals|*N-Methylaspartate|*Dendritic Spines|*Signal Transduction|Receptors, N-Methyl-D-Aspartate|Synaptic Plasticity|Long-Term Synaptic Depression|Hippocampus|Synapses|Neurons|MAP-kinase-activated kinase 2|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|NOS1AP protein, rat|Adaptor Proteins, Signal Transducing 183 nos1ap 32061134 Cardiovasc. Res. 2020 10.1093/cvr/cvaa036 0 0 0 240 Humans|Long QT Syndrome Type 1|*Arrythmia|KCNQ1 Potassium Channel|Induced Pluripotent Stem Cells|Potential, Action|Myocytes, Cardiac|*Polymorphism, Genetic|Patch-Clamp Techniques|Phenotype|Cell Line|Mutation|Heart Rate|NOS1 protein, human|Nitric Oxide Synthase Type I|NOS1AP protein, human|Adaptor Proteins, Signal Transducing 183 not 32679625 Int J Gynaecol Obstet 2020 10.1002/ijgo.13309 0 0 0 1460 Female|Humans|Neoplasm Recurrence, Local|Lymph Node|*Endometrial Cancer|Lymph Node Excision|Lymphatic Metastasis|Neoplasm Staging|Prognosis|Disease-Free Survival|Retrospective Studies|Follow-Up Studies 20720342 not 32679624 Int J Gynaecol Obstet 2020 10.1002/ijgo.13311 0 0 0 1460 Pregnancy|Female|Humans|*Diabetes, Gestational|*Glucose|*Triglycerides|Glucose Tolerance Test|Blood Glucose|Body Mass Index|Fasting|Risk Factors 20720342 not 32679623 Med Phys 2020 10.1002/mp.14403 0 0 0 1460 Humans|*Cone Beam Computed Tomography|Phantoms, Imaging|Radiographic Image Interpretation, Computer-Assisted|Image Processing, Computer-Assisted|Imaging, Three-Dimensional|Algorithms 20720342 not 32679621 Br. J. Haematol. 2020 10.1111/bjh.17034 0 0 0 1460 Humans|COVID-19|*Coronavirus|*Programmed Cell Death 1 Receptor|severe acute respiratory syndrome coronavirus 2|*Coronavirus Infection|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|fas Receptor|*Lymphocyte Count|Flow Cytometry|HIV Infections|Apoptosis 20720342 not 32679620 Biotechnol J 2020 10.1002/biot.202000100 0 0 0 1460 *Nanofibers|*Biotin|CD8-Positive T-Lymphocytes|*Adjuvants, Immunologic|CPG-oligonucleotide|Oligodeoxyribonucleotides|*Peptides|Antigens|*Adjuvants, Pharmaceutic|Immune Responses, Cellular|Cytokines 20720342 not 32679619 J. Phycol. 2020 10.1111/jpy.13051 0 0 0 1460 Ecosystem|*Seasons|*Seaweed|Fucus|Climate Change|Invasive Species|Sargassum|Temperature 20720342 not 32679618 FEBS J. 2020 10.1111/febs.15490 0 0 0 1460 Animals|mandelonitrile lyase|*Aldehyde-Lyases|cyanohydrin|*Nitriles|cyanogen|mandelonitrile|Acetonitriles|*Arthropods|Catalysis|Crystallography, X-Ray|Amino Acid Sequence|Aldehydes|Hydrogen Bonds|Models, Molecular|Stereoisomerism|Ligands 20720342 not 32679617 Liver Int. 2020 10.1111/liv.14609 0 0 0 1460 Humans|COVID-19|*SARS-CoV|severe acute respiratory syndrome coronavirus 2|Coronavirus Infections|Pneumonia, Viral|Pandemics|Betacoronavirus|Severe Acute Respiratory Syndrome|Middle East Respiratory Syndrome Coronavirus|*Hepatitis|*Registry 20720342 not 32679616 Chem Biol Drug Des 2020 10.1111/cbdd.13759 0 0 0 1460 Reactive Oxygen Species|Oxidative Stress|Mitochondria|Oxidants 20720342 not 32679615 Colorectal Dis 2020 10.1111/codi.15271 0 0 0 1460 Male|Humans|Aged|*Mesenteric Veins|*Mesocolons|Colectomy|Colon, Ascending|Colonic Neoplasms|Lymph Node Excision|*Splenic Vein|Dissection|Laparoscopy|Inferior Mesenteric Artery|Adenocarcinoma|*Anastomosis, Surgical|Ligations|Mucinous Adenocarcinoma 20720342 not 32679614 J. Neurochem. 2020 10.1111/jnc.15128 0 0 0 1460 Tomography, X-Ray Computed|Alzheimer Disease|*Biomarkers|Neurofilament Proteins|symmetric dimethylarginine|Arginine|N,N-dimethylarginine|*Plasma|Cohort Studies|Citrulline|Positron Emission Tomography|Kynurenine|*Cognition|Brain 20720342 not 32679613 Reprod. Domest. Anim. 2020 10.1111/rda.13775 0 0 0 1460 Swine|Animals|*CRISPR-Cas Systems|Genome Editing|*CRISPR|Animals, Genetically Modified|Nuclear Transfer Techniques|Gene Knockout Techniques|Cloning, Organism|Myostatin|Swine, Miniature|Phenotype|Genome|Breeding|Mutation|Cells, Cultured|China 20720342 not 32679612 Liver Transpl. 2020 10.1002/lt.25848 0 0 0 1460 Humans|*Hepatectomy|*Tissue and Organ Harvesting|*Laparoscopy|Living Donors|Liver Transplantation|*Liver|Operative Time|Postoperative Complications|Retrospective Studies 20720342 not 32679611 Transbound Emerg Dis 2020 10.1111/tbed.13735 0 0 0 1460 Animals|Humans|Brucellosis|Brucella abortus|Animals, Wild|Zoonotic Disease|Bison|Livestock|Goats|Arctic Regions 20720342 not 32679610 Mol Oncol 2020 10.1002/1878-0261.12765 0 0 0 1460 Mice|Animals|Humans|*Telomerase|*Epithelial-Mesenchymal Transition|*Colorectal Cancer|MicroRNAs|Exosomes|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Proliferation|Wnt Signaling Pathway|Liver Neoplasms|Tumor Microenvironments 20720342 not 32679609 J Eur Acad Dermatol Venereol 2020 10.1111/jdv.16826 0 0 0 1460 Humans|*Dermatomyositis|*Sunburn|*Suntan|Skin|Muscle Weakness|*Hispanic 20720342 not 32679608 Pediatr Allergy Immunol 2020 10.1111/pai.13323 0 0 0 1460 Humans|Lymphohistiocytosis, Hemophagocytic|Mutation|*Immunologic Deficiency Syndromes|Membrane Proteins|Introns|Cytotoxic T-Lymphocytes|Natural Killer Cells|FHL3 protein, human|Intracellular Signaling Peptides and Proteins|LIM Domain Proteins|UNC13D protein, human 20720342 not 32679607 J Eur Acad Dermatol Venereol 2020 10.1111/jdv.16824 0 0 0 1460 Humans|*Melanocytic Nevi|Melanoma|Skin Neoplasms 20720342 not 32679606 Chem Biol Drug Des 2020 10.1111/cbdd.13764 0 0 0 1460 Ligands|Molecular Docking Simulation|Software|Protein Binding|Proteins|Algorithms|Drug Design|*Biophysical Phenomena 20720342 not 32679604 Drug Res (Stuttg) 2020 10.1055/a-1206-6757 0 0 0 1460 Mice|Animals|*Morphine|dihydromyricetin|Dependence, Morphine|*Flavonols|Naloxone|Conditioning, Operant|Conditioning, Psychological|Analgesics, Opioid|*Flavonoids|*Conditioning, Classical|Dose-Response Relationship, Drug|Behavior, Animal|Motor Activity|*Substance-Related Disorders 20720342 NOVA1 32589614 Aging (Albany NY) 2020 10.18632/aging.103266 0 0 0 155 Humans|Mice|Animals|Nova antigen|Diabetes Mellitus, Type 2|Quality of Life|*RNA-Binding Proteins|NOVA1 protein, human|*Fibroblasts|Cell Movement|*Nerve Tissue Proteins|Cell Proliferation|MicroRNAs|3' Untranslated Regions|Apoptosis|Down-Regulation|Wound Healing|siRNA|MIRN27 microRNA, human|Mirn27 microRNA, mouse 87 NOVA1 32486302 Int J Mol Sci 2020 PMC7312376 10.3390/ijms21113941 0 0 0 155 *Alternative Splicing|Endothelial Cells|NOVA1 protein, human|RNA-Binding Proteins|NOVA2 protein, human|Nerve Tissue Proteins|Pre-mRNA|*Gene Expression|Pathfinding, Axon|Neurons|RNA Splicing|Exons|mRNA|Introns|Cerebral Cortex|Synapses|Antigens, Neoplasm|Cerebellum 87 NOVA1 32317088 BMB Rep 2020 PMC7262508 0 0 0 155 Humans|histone H3 trimethyl Lys4|*Histones|*Histone Code|*Triple Negative Breast Neoplasms|*Protein Processing, Post-Translational|Chromatin Immunoprecipitation|Epigenesis, Genetic|Methylation|Lysine|Promoter Regions, Genetic|Gene Expression 87 NOVA1 32101070 RNA Biol 2020 10.1080/15476286.2020.1734372 1 0 0 155 *Epithelial-Mesenchymal Transition|Nova antigen|*RNA-Binding Proteins|NOVA2 protein, human|NOVA1 protein, human|beta Catenin|*Catenins|Nerve Tissue Proteins|Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|Cadherins|Cell Line, Tumor|mRNA Stability|Alternative Splicing|Transcriptional Activation 87 NOVA1 32016460 Mol Med Rep 2020 10.3892/mmr.2020.10949 1 0 0 155 *Alternative Splicing|*Stomach Neoplasms|NOVA1 protein, human|RNA-Binding Proteins|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cancer Microenvironment|Oncogene|Cell Proliferation|Apoptosis 87 NOVA1 31913086 J. Psychopharmacol. (Oxford) 2020 10.1177/0269881119895534 1 0 0 155 *Bipolar Disorder|*MicroRNAs|*Neurite Outgrowth 87 NPAS1 32273286 G3 (Bethesda) 2020 PMC7263688 10.1534/g3.120.401126 0 0 0 55 Animals|Caenorhabditis elegans Proteins|Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|Caenorhabditis elegans|Gene Expression Regulation, Developmental|Neurogenesis|Nervous System|Neurons|Nerve Tissue Proteins|Cell Differentiation 35 npas4 32479993 Brain Behav. Immun. 2020 10.1016/j.bbi.2020.05.070 1 0 0 180 Mice|Animals|Alzheimer Disease|Plaque, Amyloid|Amyloid beta-Protein Precursor|Presenilin-1|Amyloid beta-Peptides|Mice, Transgenic|Microglia|Hippocampus|Disease Models, Animal|Brain|Disease Progression 169 npas4 32468095 Cell. Mol. Life Sci. 2020 10.1007/s00018-020-03553-4 0 0 0 180 Humans|Middle Aged|Mice|Animals|Hippocampus|Long-Term Potentiation|Maze Learning|Neurons|Cognition|*Attention 169 npas4 32327470 eNeuro 2020 PMC7262005 10.1523/ENEURO.0322-19.2020 0 0 0 180 Humans|*Amyloid beta-Protein Precursor|Alzheimer Disease|Senile Plaques|Neurons|Synapses|Neuronal Plasticity|Brain|*Transcription Factor|gamma-Aminobutyric Acid|NPAS4 protein, human|Basic Helix-Loop-Helix Transcription Factors 169 npas4 32309111 3 Biotech 2020 PMC7154046 10.1007/s13205-020-02190-9 0 0 0 180 Rats|Animals|*RNA, Long Noncoding|*Dexmedetomidine|*Postoperative Cognitive Complications|*Whole Exome Sequencing|NF-kappa B|Hippocampus|mRNA|Signal Transduction|MicroRNAs|Microglia|Neurogenesis|Neurons|Cognitive Dysfunction|Apoptosis|Downregulation|Cytokines|Cell Proliferation 169 npas4 32296859 Psychopharmacology (Berl.) 2020 10.1007/s00213-020-05498-9 0 0 0 180 Humans|*Antipsychotic Agents|blonanserin|*Piperazines|*Piperidines|Receptors, Dopamine D3|Dopamine Antagonists|Schizophrenia|Brain|Prefrontal Cortex 169 npas4 32218277 Molecules 2020 PMC7181211 10.3390/molecules25071484 0 0 0 180 Animals|Mice|*Catechin|*Green Tea|*Longevity|*Genes, Immediate-Early|*Hippocampus|*Cognitive Decline|Memory|Aging|Camellia sinensis|Learning|Oxidative Stress|Antioxidants 169 npas4 32190129 Behav Neurol 2020 PMC7072106 10.1155/2020/7830469 0 0 0 180 Female|Mice|Animals|*Maternal Deprivation|Social Behavior|Stress, Psychological|Neuronal Plasticity|Anxiety|Prefrontal Cortex|Hippocampus|Animals, Newborn|Brain 169 npas4 32187527 Cell 2020 PMC7166195 10.1016/j.cell.2020.02.055 0 0 0 180 Animals|Mice|*Memory|*Neurons|Fear|Dentate Gyrus|Interneurons|Entorhinal Cortex|Mice, Inbred C57BL|Brain 169 npas4 32183629 Proc. Biol. Sci. 2020 PMC7126027 10.1098/rspb.2019.2922 0 0 0 180 Animals|*Bass|Hydrocortisone|Stress, Physiological|Stress, Psychological|*Seafood|Cognition 169 npas4 32099100 Mol. Psychiatry 2020 10.1038/s41380-020-0693-9 0 0 0 180 Humans|Mice|Animals|DNA Copy Number Variations|Autism Spectrum Disorder|Chromosome Disorders|Intellectual Disability|Chromosome Duplication|Chromosome Deletion|*Synapse|*Disease Models, Animal|Phenotypes|Schizophrenia|Genotype|Heterozygote|*Chromosome Structures|gamma-Aminobutyric Acid|NPAS4 protein, human|Basic Helix-Loop-Helix Transcription Factors|Npas4 protein, mouse 169 npas4 31936294 Nutrients 2020 PMC7019546 10.3390/nu12010174 1 0 0 180 Humans|Male|Animals|Mice|theanine|*Glutamates|*Neurodegenerative Diseases|*Atrophy|Tea|Aging|*Amino Acids|Brain|*Brain Diseases 169 npas4 31930559 FASEB J. 2020 10.1096/fj.201902257RR 0 0 0 180 Mice|Animals|*Serum Response Factor|*Neurons|*Traumatic Brain Injury|Transcription Factors|Gene Expression Regulation|neuronal pentraxin|Nerve Tissue Proteins|Transcription, Genetic|Genes, Immediate-Early|Epilepsy|Transcriptional Activation|*Psychomotor Agitation|C-Reactive Protein 169 NPAT 32425970 Front Genet 2020 PMC7204400 10.3389/fgene.2020.00337 0 0 0 187 *Exome|Telomeres|Leukocytes|Genetic Variation|Whole Exome Sequencings|*Genetic Testing 121 NPAT 32328548 J Can Assoc Gastroenterol 2020 PMC7165262 10.1093/jcag/gwy073 0 0 0 187 Humans|*Colonoscopy|Pain Measurement|Conscious Sedation|Patient Satisfaction|Reproducibility of Results|Prospective Studies|Patient Compliance 121 NPAT 32111032 Int J Mol Sci 2020 PMC7084650 10.3390/ijms21051586 0 0 0 187 Animals|*Hemocytes|*Larvae|*Histones|*Hyperplasia|Drosophila Proteins|Drosophila melanogaster|Tumor Suppressor Proteins|*Lymph Nodes|Mutations|*Intranuclear Inclusion Bodies 121 NPAT 31980612 Nat Commun 2020 PMC6981281 10.1038/s41467-020-14353-6 1 0 0 187 Humans|Animals|Mice|*Alzheimer Disease|Amyloid beta-Peptides|Amyloid beta-Protein Precursor|*Disease Models, Animal|tau Proteins|Mice, Transgenic|Neurons|*Necrosis|MARCKS protein, human|Myristoylated Alanine-Rich C Kinase Substrate|Brain|Cognitive Impairment|Phosphorylation|Cell Death 121 NPAT 31959475 Biochem. Biophys. Res. Commun. 2020 10.1016/j.bbrc.2019.12.097 0 0 0 187 Humans|Animals|Mice|*Intellectual Disability|X-Ray Microtomography|*Bone Development|Neural Stem Cells|Bone Formation|Nuclear Proteins|Carrier Proteins|Microcephaly|NES protein, human|Nestin|Bone Marrow Mesenchymal Stem Cells|Cell Cycle|Chondrocyte|PQBP1 protein, human|Pqbp1 protein, mouse 121 nppb 32663504 Biochim Biophys Acta Mol Cell Res 2020 10.1016/j.bbamcr.2020.118796 0 0 0 902 *Zoxazolamine|*Embryonic Stem Cells|Calcium Signaling|Myocytes, Cardiac|Cell Differentiation|Calcium|Cell Line|Adenosine Triphosphate 1320 nppb 32638546 J. Cell. Mol. Med. 2020 10.1111/jcmm.15544 0 0 0 902 *Heart Failure|Gene Expression Profiling|Biomarkers|Transcriptome|Transcription Factors|Systems Biology|Databases, Genetic|Signal Transduction 1320 nppb 32616194 Chin J Nat Med 2020 10.1016/S1875-5364(20)30064-9 0 0 0 902 Rats|Animals|Shen-Fu|Molecular Docking Simulation|*Drugs, Chinese Herbal|*Heart Failure|angiotensin converting enzyme 2|Angiotensin Converting Enzyme 1320 nppb 32556416 Cell. Mol. Life Sci. 2020 10.1007/s00018-020-03573-0 0 0 0 902 Epigenesis, Genetic|*Natriuretic Peptides|Receptors, Atrial Natriuretic Factor|Atrial Natriuretic Factor|Natriuretic Peptide, Brain|Gene Expression|MicroRNAs|Protein Processing, Post-Translational|Cardiovascular Diseases 1320 nppb 32555714 PLoS ONE 2020 PMC7299387 10.1371/journal.pone.0234547 0 0 0 902 Humans|*Roma|*Risk Factors|Cross-Sectional Studies|Hungary|Genetic Susceptibility|SNPs|Frequencies, Allele|*Hypertension|Genotype|Alleles|Cardiovascular Diseases|Prevalence|Europe 1320 nppb 32509185 Am J Transl Res 2020 PMC7269983 0 0 0 902 *Myocytes, Cardiac|*Hyperuricemia|*Autophagy|Autophagy-Related Protein-1 Homolog|AMP-Activated Protein Kinases|TOR Serine-Threonine Kinases|Signal Transduction|Hypertrophy 1320 nppb 32456708 BMC Res Notes 2020 PMC7249366 10.1186/s13104-020-05101-6 0 0 0 902 Animals|*Onchocerciasis|Sudan|Cross-Sectional Studies|Onchocerca volvulus|Simuliidae|Disease Eradication|Tropical Medicine|Socioeconomic Factors 1320 nppb 32393661 Cancer Res. 2020 10.1158/0008-5472.CAN-19-3534 0 0 0 902 Humans|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|Chronic Pancreatitis|*Fibroblasts|*Pancreas|Adenocarcinoma|Gene Expression Regulation, Neoplastic 1320 nppb 32380038 Exp. Cell Res. 2020 10.1016/j.yexcr.2020.112059 0 0 0 902 Humans|Mice|Rats|Animals|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|EZH2 protein, human|*Enhancer of Zeste Homolog 2 Protein|Endothelial Cells|*Cardiac Hypertrophy|*Signal Transduction|Cardiomyocytes|Angiotensin II|NPPA protein, human|Atrial Natriuretic Factor|Upregulation|Ligase, Ubiquitin-Protein|MicroRNAs|*Genes, Regulator|siRNA|Transcription Factors|SIX1 protein, human 1320 nppb 32352932 JCI Insight 2020 PMC7308051 10.1172/jci.insight.137393 0 0 0 902 Male|Female|Mice|Animals|F2rl1 protein, mouse|*Receptor, PAR-2|*Pain|Hyperalgesia, Thermal|Ganglia, Spinal|Sensory Neuron|Mice, Inbred C57BL|Mice, Knockout 1320 nppb 32333115 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. 2020 10.1007/s00360-020-01277-2 0 0 0 902 Animals|*Gills|*Brachyura|*Ion Transport|*Hypoxia|*Epithelium|Sodium-Potassium-Exchanging ATPase|Water-Electrolyte Balance|Seawater|Sodium Chloride 1320 nppb 32324169 JCI Insight 2020 PMC7205432 10.1172/jci.insight.133675 0 0 0 902 Humans|Mice|Animals|*Natriuretic Peptide, Brain|*c-jun N-Terminal Kinase|Sepsis|Shock, Septic|*Hypotension|Heart Failure|Heart|Ventricular Dysfunction, Left|Biomarkers|*Upregulation|Heart Ventricles|*Transcriptional Activation|Cardiac Output|Blood Pressure 1320 nppb 32309366 Ann Transl Med 2020 PMC7154424 10.21037/atm.2020.01.51 0 0 0 902 Mice|Animals|*Aortic Valve Insufficiency|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|*beta-Arrestin 1|*Proto-Oncogene Proteins c-akt|*Heart Ventricles|Ventricular Remodeling|Ventricular Function, Left|Hypertrophy, Left Ventricular|Stroke Volume|Echocardiography|Disease Models, Animal 1320 nppb 32268102 Cell Rep 2020 10.1016/j.celrep.2020.03.036 0 0 0 902 Humans|Mice|Dogs|Animals|*Pruritus|POSTN protein, human|*Cell Adhesion Molecules|Atopic Dermatitis|*Sensory Neurons|Skin|*Integrins|Keratinocytes|Cytokines|*Hypersensitivity 1320 nppb 32247607 Biochem. 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Commun. 2020 10.1016/j.bbrc.2020.03.115 0 0 0 902 Rats|Animals|*Channel, Chloride|*Reactive Oxygen Species|Acute Disease|Acute Pancreatitis|4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid|Patch-Clamp Techniques|Membrane Potentials|*Acinar Cells|*Pancreas, Exocrine|*Epithelial Cells|Hydrogen-Ion Concentration 1320 nppb 32235125 Ophthalmic Res. 2020 10.1159/000507632 0 0 0 902 ClC-2 chloride channels|*Collagen|*Fibroblasts|Chloride Channels|*Conjunctiva|Collagen Type I|Cells, Cultured|Fibronectins|Cell Proliferation|Scarring|Signal Transduction 1320 nppb 32221845 Neurosci Bull 2020 PMC7340684 10.1007/s12264-020-00486-7 1 0 0 902 *Nociceptors|*NFI Transcription Factors|*Fiber, A|Ganglia, Spinal|C Fiber|Sensory Neurons|Action Potentials|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Neuropeptide Y Receptor 1320 nppb 32066374 J Physiol Sci 2020 PMC7026216 10.1186/s12576-020-00740-7 0 0 0 902 Humans|*Channel, Chloride|*Stomach Neoplasms|Whole-Cell Recordings|Membrane Potentials|Cell Line|Plasma Membrane|CLIC3 protein, human 1320 nppb 32000690 BMC Med Res Methodol 2020 PMC6993446 10.1186/s12874-020-0908-4 0 0 0 902 Humans|*Questionnaire|Psychometric|Factor Analysis, Statistical|Reproducibility of Results 1320 nppb 31948841 Neurocirugia (Astur) 2020 10.1016/j.neucir.2019.11.002 0 0 0 902 Animals|Rats|*Brain Ischemia|*Reperfusion|*Perfusion|Cerebrovascular Circulation|Malformations, Intracranial Arteriovenous|Blood-Brain Barrier|Brain|Homeostasis|Disease Models, Animal 1320 NPTX1 32487172 Part Fibre Toxicol 2020 PMC7268298 10.1186/s12989-020-00352-4 0 0 0 493 Animals|Humans|*Particulate Matter|Air Pollutants|Air Pollution|Particle Size|Oxidative Stress|Mitochondria|Apoptosis|Inflammation 39 NPTX1 32357304 J. Proteome Res. 2020 10.1021/acs.jproteome.0c00137 0 0 0 493 Humans|Animals|Rats|*Tauopathies|tau Proteins|Alzheimer Disease|*Brain 39 NPTX1 32273328 J. Neurol. Neurosurg. Psychiatry 2020 PMC7279197 10.1136/jnnp-2019-322493 0 0 0 493 *Frontotemporal Dementia|neuronal pentraxin|*Pick Disease of the Brain|C-Reactive Protein|C9orf72 Protein|*Biomarkers|Neurofilament Proteins|tau Proteins|*Synapse|Mutation 39 NPTX1 32255252 FEBS J. 2020 10.1111/febs.15325 0 0 0 493 Humans|*RNA, Long Noncoding|*Transcription Factor, NFKB1|*Glioma|*Upregulation|Brain Tumors|Gene Expression Regulation, Neoplastic|Cell Proliferation|MicroRNAs|Cell Line, Tumor|Prognosis|*Angiogenesis Inhibitors|Apoptosis|NFKB1 protein, human|SLC26A4 protein, human|Sulfate Transporters 39 NPTX2 32614981 J. Neurochem. 2020 10.1111/jnc.15116 0 0 0 198 Animals|Humans|*Alzheimer Disease|*Proteomics|Chromatography, Liquid|Neurodegenerative Diseases|Tandem Mass Spectrometry|Proteome|*Frontal Cortex|Brain|Disease Models, Animal|Neurofibrillary Tangles|SMOC1 protein, human|Osteonectin|DUSP26 protein, human|Dual-Specificity Phosphatases|Mitogen-Activated Protein Kinase Phosphatases 84 NPTX2 32552841 Mol Neurodegener 2020 PMC7301448 10.1186/s13024-020-00388-2 0 0 0 198 *Lewy Body Disease|*Proteomics|Alzheimer Disease|Amyloid beta-Peptides|tau Proteins|*Biomarkers|Peptide Fragments|alpha-Synuclein|Diagnosis, Differential 84 NPTX2 32396526 Aging (Albany NY) 2020 PMC7244061 10.18632/aging.103028 0 0 0 198 Mice|Animals|*Pars Compacta|*Dopaminergic Neurons|*Parkinson Disease|HOTAIR long untranslated RNA, human|*RNA, Long Noncoding|Substantia Nigra|*Autophagy|*Mesencephalon|1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|*Disease Models, Animal|1-Methyl-4-phenylpyridinium|Mice, Inbred C57BL|MicroRNAs|Apoptosis|Cell Line, Tumor 84 NPTX2 32273328 J. Neurol. Neurosurg. Psychiatry 2020 PMC7279197 10.1136/jnnp-2019-322493 0 0 0 198 *Frontotemporal Dementia|neuronal pentraxin|*Pick Disease of the Brain|C-Reactive Protein|C9orf72 Protein|*Biomarkers|Neurofilament Proteins|tau Proteins|*Synapse|Mutation 84 NPTX2 32146565 J. Cancer Res. Clin. Oncol. 2020 10.1007/s00432-020-03169-y 1 0 0 198 Humans|*Circulating DNA|Osteonectin|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Promoter Regions, Genetic|CpG Islands|DNA Methylation|Chronic Pancreatitis|preproenkephalin|Protein Precursors|UCHL1 protein, human|Ubiquitin Carboxy-Terminal Hydrolase|Enkephalins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|proenkephalin|Nerve Tissue Proteins 84 NPTX2 32066474 J Neuroinflammation 2020 PMC7025403 10.1186/s12974-020-1723-x 0 0 0 198 *Alzheimer Disease|*Chitinase|*Disease Progression|*Frontal Cortex|Biomarkers|Brain 84 NPTX2 31969807 Front Cell Neurosci 2020 PMC6960182 10.3389/fncel.2019.00575 0 0 0 198 neuronal pentraxin|*Neuropathology|Nerve Tissue Proteins|C-Reactive Protein|Synaptic Plasticity|Synapses|*Signal Transduction|Receptors, AMPA|Neurons|Synaptic Transmission|Hippocampus|Immediate-Early Gene|*Nervous System Diseases 84 NPTX2 31930559 FASEB J. 2020 10.1096/fj.201902257RR 0 0 0 198 Mice|Animals|*Serum Response Factor|*Neurons|*Traumatic Brain Injury|Transcription Factors|Gene Expression Regulation|neuronal pentraxin|Nerve Tissue Proteins|Transcription, Genetic|Genes, Immediate-Early|Epilepsy|Transcriptional Activation|*Psychomotor Agitation|C-Reactive Protein 84 NREP 32250344 J. Clin. Invest. 2020 PMC7190992 10.1172/JCI127502 1 0 0 155 Humans|Mice|Animals|*Lipid Metabolism|*Metabolic Syndrome|*Liver|Nonalcoholic Fatty Liver Disease|Lipogenesis|Diet, High-Fat|Insulin Resistance|Lyase, ATP Citrate|GDF15 protein, human|Growth Differentiation Factor 15|Hyperglycemia|Acetyl-CoA 46 NUCKS1 32014019 Clin Epigenetics 2020 PMC6998837 10.1186/s13148-020-0814-y 0 0 0 269 *Alzheimer Disease|*Quantitative Trait Loci|DNA Methylation|Epigenesis, Genetic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Epigenetic|Epistasis, Genetic 35 NUCKS1 31914803 Artif Cells Nanomed Biotechnol 2020 10.1080/21691401.2019.1652629 0 0 0 269 35 NUPR1 32619170 Curr Cancer Drug Targets 2020 10.2174/1568009620666200703152523 0 0 0 368 Carcinoma, Hepatocellular|Neoplasm Proteins|Liver Neoplasms|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction 162 NUPR1 32574111 Am. J. Physiol. Endocrinol. Metab. 2020 10.1152/ajpendo.00088.2020 0 0 0 368 Mice|Animals|*Insulin Secretion|*Streptozocin|*Diet, High-Fat|Insulin|Insulin-Secreting Cells|Pancreatic Islets|Insulin Resistance|Glucose Intolerance|Blood Glucose|Obesity|*Pancreas|Mice, Transgenic|Apoptosis|Nupr1 protein, mouse|DNA-Binding Proteins|Neoplasm Proteins 162 NUPR1 32513898 Mol. Cancer Res. 2020 10.1158/1541-7786.MCR-20-0051 0 0 0 368 Humans|Male|*Docetaxel|*Transcriptome|*Single-Cell Analysis|*Prostate|Drug Resistance, Neoplasm|Taxoids|PC3 Cell Line|Prostatic Neoplasms, Castration-Resistant|Cell Line, Tumor|Antineoplastic Agents|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|Apoptosis|Nuclear Proteins 162 NUPR1 32446862 Cancer Lett. 2020 10.1016/j.canlet.2020.04.024 0 0 0 368 Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Sorafenib|Phenylurea Compounds|Niacinamide|Apoptosis|Cell Proliferation|Hep G2 Cells|Gene Expression Regulation, Neoplastic|Apoptosis Regulatory Proteins|Antineoplastic Agents|Necrosis|Cell Line, Tumor|Mitochondria|Cell Death|Cell Cycle|Nupr1 protein, mouse|DNA-Binding Proteins 162 NUPR1 32266819 Neoplasma 2020 10.4149/neo_2020_190814N759 0 0 0 368 Humans|Mice|Animals|*Down-Regulation|Mice, Nude|*Glioma|*Cell Cycle Arrest|*G0 Phase|Cell Proliferation|CCNE1 protein, human|Cyclin E|Cell Cycle|*Cell Nucleus|Gene Knockdown Techniques|Apoptosis|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cell Line, Tumor|RNA, Small Interfering|G1 Phase|Nuclear Protein 162 NUPR1 32191629 Aging (Albany NY) 2020 PMC7138556 10.18632/aging.102942 0 0 0 368 Humans|Rats|Animals|*Sevoflurane|IGFBP5 protein, human|*Insulin-Like Growth Factor Binding Protein 5|*Signal Transduction|MicroRNAs|Apoptosis|Hippocampus|Downregulation|Neurons|*CCAAT-Enhancer-Binding Proteins|Methyl Ethers|Rats, Sprague-Dawley|*Memory Disorders|Maze Learning|Memory|Endoplasmic Reticulum Stress|Animals, Newborn|MIRN325 microRNA, human 162 NUPR1 32156385 Food Res. Int. 2020 10.1016/j.foodres.2019.108938 0 0 0 368 Humans|*Passiflora|Refuse Disposal|*Seeds|Metabolomics|Polyphenols|HT 29 Cells|Fruit|Colon Cancer|Transcriptome Analysis|Cell Cycle|Polyamines|Genes, cdc|Phases, M 162 NUPR1 32008055 J. Mol. Med. 2020 PMC7080693 10.1007/s00109-020-01875-1 0 0 0 368 Pregnancy|Male|Female|Humans|Infant, Newborn|Rats|Animals|*Fetal Growth Retardation|*Infant, Small for Gestational Age|Low Protein Diet|Uterus|Animals, Newborn|Kidney|Ligation|Kidney Diseases|*Organogenesis|LTB4R2 protein, human|Receptors, Leukotriene B4|PILRA protein, human|Membrane Glycoproteins|Receptors, Immunologic|Nupr1 protein, rat|Neoplasm Proteins|Basic Helix-Loop-Helix Transcription Factors 162 NUPR1 31971825 DNA Cell Biol. 2020 10.1089/dna.2019.5196 0 0 0 368 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Multiple Myeloma|MTOR protein, human|*TOR Serine-Threonine Kinases|Apoptosis|Autophagy|Phosphoinositide-3 Kinase Inhibitors|Signal Transduction|Cell Proliferation|Cell Line, Tumor|Chloroquine|*Autophagic Cell Death|3-methyladenine|Adenine 162 NUPR1 31922247 Oncol. Rep. 2020 10.3892/or.2020.7455 0 0 0 368 Mice|Animals|Humans|*Mice, Nude|*Trifluoperazine|*Nuclear Protein|*Lung Adenocarcinoma|Lung Cancer|shRNA|Neoplasm Proteins|Cell Line, Tumor|Genetic Therapy|Cell Proliferation|Basic Helix-Loop-Helix Transcription Factors|Nupr1 protein, mouse|DNA-Binding Proteins 162 NUPR1 31914690 FASEB J. 2020 10.1096/fj.201902086R 0 0 0 368 Male|Humans|Rats|Animals|*Erectile Dysfunction|MIRN874 microRNA, mouse|*Diabetes Mellitus, Experimental|Quality of Life|*MicroRNAs|Penile Erection|DDIT3 protein, human|*Transcription Factor CHOP|Streptozocin|Rats, Sprague-Dawley|Apoptosis|Signal Transduction|Disease Models, Animal|*Epigenesis, Genetic|MIRN874 microRNA, human|Nupr1 protein, rat|Neoplasm Proteins|Basic Helix-Loop-Helix Transcription Factors 162 NUPR1 31905765 Int J Mol Sci 2020 PMC6982268 10.3390/ijms21010237 0 0 0 368 Humans|*Thyroid Carcinoma, Anaplastic|lenvatinib|exportin 1 protein|*Phenylurea Compounds|*Karyopherins|*Quinolines|*Receptors, Cytoplasmic and Nuclear|Protein Kinase Inhibitors|Thyroid Carcinomas|Antineoplastic Agents|Xenograft Model Antitumor Assays|Signal Transduction|Cell Line, Tumor|Cell Proliferation|Export, Nuclear|Cell Survival|Apoptosis|PAK4 protein, human 162 NUSAP1 32651974 Bosn J Basic Med Sci 2020 10.17305/bjbms.2020.4701 0 0 0 221 Humans|Female|Neoplasm Recurrence, Local|*Wnt Pathway|Epithelial-Mesenchymal Transition|Cell Movement|*Catenins|*Microtubule-Associated Proteins|Cell Proliferation|Gene Expression Regulation, Neoplastic|Prognosis|Cell Line, Tumor 83 NUSAP1 32440821 J. 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Neurosci. 2020 10.1007/s12031-020-01587-8 0 0 0 221 Humans|Child|*Computational Biology|*Rhabdoid Tumor|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Carcinoma, Hepatocellular|Databases, Genetic|Gene Expression Profiling|Liver Neoplasms|Protein Interaction Mapping|Profile, Gene Expression|Genes, cdc|Gene Expression Regulation, Neoplastic|Microarray Analysis|NDC80 protein, human|Nuclear Proteins|Biomarkers, Tumor|Cell Cycle Proteins 83 NUSAP1 32420375 Biomed Res Int 2020 PMC7206867 10.1155/2020/8604340 0 0 0 221 Humans|Phosphatidylinositol 3-Kinases|Gene Ontology|Gene Expression Profiling|Prognosis|Protein Interaction Maps|Computational Biology|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Databases, Genetic|Biomarkers, Tumor|Transcriptome|Software|Microarray Analysis|Signal Transduction 83 NUSAP1 32317623 Signal Transduct Target Ther 2020 PMC7174393 10.1038/s41392-020-0137-7 0 0 0 221 Humans|*Glioblastoma|*Drug Resistance, Neoplasm|Temozolomide|Sumoylation|Protein Inhibitors of Activated STAT|Ubiquitin Ligase E3|Ubiquitination|Microtubule-Associated Proteins|Proteolysis|Cell Proliferation|ATR protein, human|Ataxia Telangiectasia Mutated Proteins 83 NUSAP1 32309435 Biomed Res Int 2020 PMC7140147 10.1155/2020/5762932 0 0 0 221 Mice|Animals|*Osteogenesis|*RAW 264.7 Cells|TNFSF11 protein, human|RANK Ligand|Osteoclasts|*Transcriptome Analysis|Cell Differentiation|NFATC Transcription Factors|*Magnetic Field|Gene Ontology|Cells, Cultured|Downregulation 83 NUSAP1 32298762 Gene 2020 10.1016/j.gene.2020.144657 0 0 0 221 Humans|*Triple-Negative Breast Cancer|*Prognosis|Epithelial-Mesenchymal Transition|Wnt Signaling Pathway|*Catenins|beta Catenin|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Up-Regulation 83 NUSAP1 32256749 Exp Ther Med 2020 PMC7086186 10.3892/etm.2020.8522 0 0 0 221 Humans|*Carcinoma, Hepatocellular|thymidine kinase 1|*Liver Neoplasms|*Prognosis|*Thymidine Kinase|Gene Ontology|Bioinformatics|*Disease Progression|Gene Regulatory Networks|*Cyclin B1|Protein Interaction Maps|Databases, Genetic|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Protein Interaction Mapping|Cyclin B2|Transcriptome|Genes, cdc 83 NUSAP1 32233835 Technol. 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Treat. 2020 PMC7132787 10.1177/1533033820905823 0 0 0 221 Female|Pregnancy|Humans|*RNA, Long Noncoding|*Proto-Oncogene Proteins c-akt|*Cell Line, Tumor|MTOR protein, human|*TOR Serine-Threonine Kinases|Cell Proliferation|Signal Transduction|Apoptosis|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Cycle Arrest|Cell Movement|Downregulation|Gene Expression Regulation, Neoplastic|Phosphorylation|Choriocarcinoma|RNA, Small Interfering|Cell Cycle 83 NUSAP1 32226503 J Cancer 2020 PMC7086256 10.7150/jca.34640 0 0 0 221 83 NUSAP1 32153633 Front Genet 2020 PMC7046836 10.3389/fgene.2020.00045 0 0 0 221 *Transcriptome|*Colorectal Cancer|Gene Ontology|Gene Expression Regulation, Neoplastic|Protein Interaction Maps|Gene Expression Profiling|Databases, Genetic|Signal Transduction|Computational Biology|Biomarkers, Tumor|*Colonic Neoplasms|Cell Line, Tumor 83 NUSAP1 32146475 Ophthalmologica 2020 10.1159/000506993 0 0 0 221 Humans|Child|*Computational Biology|*Retinoblastoma|*Sequencing, RNA|Gene Expression Profiling|Gene Ontology|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|*Tumorigenesis|*Whole Exome Sequencing|Transcriptome|*Base Sequence|Signal Transduction|Eye Neoplasms|Retinal Neoplasms|Cell Cycle 83 NUSAP1 32099387 Onco Targets Ther 2020 PMC6996025 10.2147/OTT.S237127 1 0 0 221 *Urinary Bladder Neoplasms|*Signal Transduction|*Microtubule-Associated Proteins|Cell Movement|Epithelial-Mesenchymal Transition|*Disease Progression|Cell Proliferation|Cell Line, Tumor|*Bladder|Gene Expression Regulation, Neoplastic|*Neoplastic Processes 83 NUSAP1 32046048 Int J Environ Res Public Health 2020 PMC7037431 10.3390/ijerph17031053 0 0 0 221 *Carcinoma, Hepatocellular|*Liver Neoplasms|Gene Ontology|Computational Biology|Gene Expression Profiles|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Protein Interaction Maps|Biomarkers, Tumor|Software 83 NUSAP1 32031285 J. Cell. Biochem. 2020 10.1002/jcb.29661 0 0 0 221 Female|Humans|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|Apoptosis|Cell Cycle|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Prognosis|Microtubule-Associated Proteins|Oncogenesis|shRNA 83 NUSAP1 31980218 Immunobiology 2020 10.1016/j.imbio.2019.09.007 1 0 0 221 *Autoantibodies|*Antigens, Neoplasm|*Lung Cancer|*Immunodiagnosis|Biomarkers, Tumor|Neoplasm Staging|Early Detection of Cancer|ROC Curve 83 NUSAP1 31901150 J. Clin. Lab. Anal. 2020 PMC7246360 10.1002/jcla.23193 1 0 0 221 *Urinary Bladder Neoplasms|*Cell Proliferation|*Cell Cycle|MicroRNAs|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Carcinogenesis|*Microtubule-Associated Proteins|Apoptosis|Liver Cancer|Disease Progression 83 NUSAP1 31895772 Medicine (Baltimore) 2020 PMC6946304 10.1097/MD.0000000000018445 0 0 0 221 Female|*Computational Biology|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Prognosis|Protein Interaction Maps|Databases, Genetic|Biomarkers, Tumor 83 OGFR 32640891 Exp. Biol. Med. (Maywood) 2020 10.1177/1535370220940273 0 0 0 69 Male|Rats|Animals|Enkephalin, Methionine|Naltrexone|Receptors, Opioid|Cell Proliferation|Cornea|Wound Healing|*Receptors, Growth Factor|Diabetes Mellitus 102 OGFR 32585612 Int. Immunopharmacol. 2020 10.1016/j.intimp.2020.106718 0 0 0 69 Humans|Mice|Female|Animals|*Naltrexone|*Epithelial-Mesenchymal Transition|Mice, Nude|*Uterine Cervical Neoplasms|HeLa Cells|methionine-enkephalin receptor|Receptors, Opioid|*Macrophages|Apoptosis|Cell Proliferation|Cell Line, Tumor|Macrophage Activation|IL10 protein, human|IL10|Cytokines 102 OGFR 32368758 J Cell Immunol 2020 PMC7198040 10.33696/immunology.1.018 0 0 0 69 Humans|Adult|*Naltrexone|methionine-enkephalin receptor|Receptors, Opioid|Narcotic Antagonists|*Diabetic Complications|*Cornea|Enkephalin, Methionine|Corneal Diseases|Dry Eye Disease|Diabetes Mellitus|Re-Epithelialization|Autoimmune Diseases|Wound Healing|Cell Division 102 OGFR 32171145 Int. 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Tissue Int. 2020 10.1007/s00223-020-00710-6 0 0 0 101 Mice|Animals|olfactomedin|Extracellular Matrix Proteins|Glycoproteins|Hypergravity|Soleus Muscle|*Gravity|Vestibule, Labyrinth|Signal Transduction|Myotubes|mRNA|Bone|Bone Mineral Density|RAW 264.7 Cells 31 OLFML3 31919052 Cancer Discov 2020 PMC7058515 10.1158/2159-8290.CD-19-0400 2 0 0 48 *Glioblastoma|*Tumor Microenvironment|*Microglia|Brain Neoplasms|Glioma|Neoplastic Stem Cells|Cell Line, Tumor|Carcinogenesis|Cell Proliferation|Stem Cell Self-Renewal 21 OLFML3 31910243 PLoS ONE 2020 PMC6946124 10.1371/journal.pone.0227154 0 0 0 48 Cattle|Animals|*Weight Gain|Animal Feed|Animal Nutritional Physiological Phenomena|Transcriptome|*Adipose Tissue|Breeding|Red Meat|Diet|Eating|Gene Expression Profiling|Phenotypes|Lipid Metabolism|Liver|Signal Transduction 21 ONECUT2 32377269 Dis. Markers 2020 PMC7191371 10.1155/2020/2860582 0 0 0 153 Early Detection of Cancer|*Colorectal Cancer|RNA, Long Noncoding|*Colonic Neoplasms|Gene Regulatory Networks|MicroRNAs|RNA, Messenger|Gene Expression Regulation, Neoplastic|Prognosis|Kaplan-Meier Estimate|Databases, Genetic 59 ONECUT2 32366993 Sci Rep 2020 PMC7198581 10.1038/s41598-020-64498-z 0 0 0 153 Humans|Animals|*Drosophila|Drosophila melanogaster|*Ear|Drosophila Proteins|Hearing|Presbycusis|ONECUT2 protein, human|Homeodomain Proteins|Transcription Factors|*Homeostasis|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Genes, Homeobox|Nerve Tissue Proteins|Neurons|Aging|Amos protein, Drosophila|Nerve Growth Factors 59 ONECUT2 32129880 Int. J. Cancer 2020 PMC7217064 10.1002/ijc.32946 0 0 0 153 Mice|Animals|*Stomach Neoplasms|*Up-Regulation|Mice, Nude|*DNA Methylation|*Promoter Regions, Genetic|Gastric Mucosa|Metaplasia|CpG Islands|ONECUT2 protein, human|*Homeodomain Proteins|*Transcription Factor|*Genes, Homeobox|*Transcriptional Activation|Stomach|Cell Transformation, Neoplastic|mRNA|Biomarkers, Tumor|*DNA 59 ONECUT2 32039001 Front Oncol 2020 PMC6985539 10.3389/fonc.2019.01491 0 0 0 153 Humans|Male|*Prostate Cancer|Androgen Antagonists|*Prostate|*Disease Progression|Carcinoma, Neuroendocrine|*Neovascularization, Pathologic|Cell Line, Tumor|Adenocarcinoma|*Neoplastic Processes|AURKA|Neuroendocrine Tumors|ONECUT2 protein, human|Homeodomain Proteins|Transcription Factors|Signal Transduction|*Phenotypes 59 OSR1 32659887 Cells 2020 10.3390/cells9071644 0 0 0 215 *Receptors, Calcium-Sensing|*Kidney|Solute Carrier Family 12, Member 3|WNK Lysine-Deficient Protein Kinase 1|Solute Carrier Family 12, Member 1|Protein-Serine-Threonine Kinases|Sodium-Potassium-Chloride Symporters|Blood Pressure|Phosphorylation|Potassium|Signal Transduction 326 OSR1 32652921 Curr Comput Aided Drug Des 2020 10.2174/1573409916666200712140941 0 0 0 215 *Molecular Dynamics Simulation|PAS domain kinases|Protein-Serine-Threonine Kinases|WNK Lysine-Deficient Protein Kinase 1|Phosphorylation|Signal Transduction|Intracellular Signaling Peptides and Proteins|Minor Histocompatibility Antigens|Amino Acid Sequence|*Biophysical Phenomena|Blood Pressure|Kidney|*Models, Chemical 326 OSR1 32650755 BMC Cancer 2020 10.1186/s12885-020-07125-4 0 0 0 215 Humans|Female|miRNAs|*Oncogenesis|*Oncogenes|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Biomarkers, Tumor|3' Untranslated Regions|Cell Line, Tumor|Down-Regulation|MIRN1908 microRNA, human 326 OSR1 32590948 BMC Genomics 2020 PMC7318502 10.1186/s12864-020-06852-z 0 0 0 215 Female|Male|Animals|*Ducks|*Gonad|*Transcriptome Analysis|Ovaries|Transcriptome|Testes|Sex Differentiation|Gene Expression Regulation|*Cell Differentiation|*Aquatic Organisms 326 OSR1 32425550 Onco Targets Ther 2020 PMC7191353 10.2147/OTT.S242386 0 0 0 215 *Down-Regulation|*Proto-Oncogene Proteins c-akt|*Colonic Neoplasms|*Adenocarcinoma|Neoplasm Invasiveness|*Disease Progression|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Signal Transduction|Genes, Tumor Suppressor|Colon 326 OSR1 32424721 Breast Cancer Res. Treat. 2020 10.1007/s10549-020-05671-w 0 0 0 215 Humans|*Lymphatic Metastasis|Prognosis|Axilla|Biomarkers, Tumor|Neoplasm Staging|Lymph Nodes 326 OSR1 32413057 PLoS ONE 2020 PMC7228128 10.1371/journal.pone.0232967 0 0 0 215 Humans|*Phosphorylation|*Staurosporine|HEK293 Cells|WNK Lysine-Deficient Protein Kinase 1|Protein-Serine-Threonine Kinases|Signal Transduction|Solute Carrier Family 12, Member 2|Symporters|Neurons|Hippocampus|Gene Expression Regulation 326 OSR1 32398354 Development 2020 PMC7240299 10.1242/dev.186239 0 0 0 215 Mice|Animals|*Osteogenesis|*Mice, Knockout|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteoblasts|Cell Differentiation|Chondrogenesis|Mesenchymal Stem Cells|Mesoderm|Transcription Factor|*Sternum|Gene Expression Regulation, Developmental|Ebf3 protein, mouse 326 OSR1 32289375 Gastroenterology 2020 10.1053/j.gastro.2020.03.075 0 0 0 215 *Hedgehog Proteins|*Signal Transduction|Liver|Bile Duct|*Mesenchymal Stem Cells|Fibrosis|Fibroblasts|Cholestasis|Epithelial Cells 326 OSR1 32286498 Hypertens. Res. 2020 10.1038/s41440-020-0437-x 0 0 0 215 Humans|*Sodium Chloride|PAS domain kinases|Protein-Serine-Threonine Kinases|Type II, Pseudohypoaldosteronism|*Sodium Chloride, Dietary|*Signal Transduction|WNK Lysine-Deficient Protein Kinase 1|Na-Cl Cotransporter|*Hypertension|Intracellular Signaling Peptides and Proteins|Phosphorylation|Cullin Proteins|Minor Histocompatibility Antigens|Kidney Tubules, Distal|Microfilament Proteins|Sodium 326 OSR1 32268081 Cell Rep 2020 10.1016/j.celrep.2020.03.055 1 0 0 215 Male|Female|Animals|Chick Embryo|*Sex Differentiation|*Chicken|*Transcriptome|*Gonad|Sex Determination Processes|Testis|Transcription Factors|Ovary|Gene Expression Regulation, Developmental|*Embryo, Mammalian 326 OSR1 32155325 Cancer Med 2020 PMC7196066 10.1002/cam4.2969 1 0 0 215 *Carcinoma, Squamous Cell|*Mouth Neoplasms|CpG Islands|DNA Methylation|Network, Gene|Promoter Regions, Genetic|Prognosis|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Databases, Genetic|Kaplan-Meier Analysis|Microarray Analysis 326 OSR1 32131390 Cancers (Basel) 2020 PMC7139507 10.3390/cancers12030575 1 0 0 215 Humans|Mice|Animals|Vascular Endothelial Growth Factor A|WNK Lysine-Deficient Protein Kinase 1|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|*Neovascularization, Pathologic|Phosphorylation|Solute Carrier Family 12, Member 2|Minor Histocompatibility Antigens|Signal Transduction|*Neoplastic Processes|Transcription Factors|Zebrafish|*Tumor|WNK1 protein, human|Wnk1 protein, mouse 326 OSR2 32623954 J. 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Res. 2020 10.1177/0022034520935372 0 0 0 68 Mice|Animals|*Osteogenesis|Palate|Morphogenesis|Cleft Palate, Isolated|Transcription Factors|Gene Expression Regulation, Developmental|Cell Proliferation|Mesoderm|Signal Transduction|TYRP1 protein, human|*Membrane Glycoproteins|Apoptosis|Cell Differentiation 79 OSR2 32555395 Sci Rep 2020 PMC7299953 10.1038/s41598-020-66872-3 0 0 0 68 Humans|Female|*Exosomes|*Endometrial Cancer|Gene Expression Profiling|Bioinformatics|Gene Ontology|Protein Interaction Maps|*Disease Progression|miRNAs|Gene Expression Regulation, Neoplastic|Downregulation|Profile, Gene Expression|Up-Regulation|Signal Transduction|Endometrium|Biomarkers, Tumor|Microarray Analysis|Cell Cycle|Survival Analysis 79 OSR2 32086979 Cancer Sci. 2020 PMC7226181 10.1111/cas.14359 1 0 0 68 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Down-Regulation|Oncogenesis|Up-Regulation|Apoptosis|MIRN361 microRNA, human 79 OTOF 32555439 Sci Rep 2020 PMC7299968 10.1038/s41598-020-66877-y 0 0 0 118 Child|Humans|Auditory neuropathy|*Prognosis|*Hearing Loss, Central|Hearing Loss, Sensorineural|Thresholds, Auditory|Otoacoustic Emissions, Spontaneous|Evoked Potentials, Auditory, Brain Stem|Cochlear Nerve|Audiometry, Pure-Tone|Vestibulocochlear Nerve Diseases|Cochlear Implantation|Hearing Loss|OTOF protein, human|Membrane Proteins 179 OTOF 32508568 Front Neurosci 2020 PMC7253664 10.3389/fnins.2020.00447 0 0 0 118 Humans|*Cochlear Implantation|Auditory neuropathy|Hearing Loss, Central|Hearing Loss, Sensorineural|Hearing Loss|Mutations|Deafness|Auditory Nerve|Hearing Aids|Membrane Proteins|Phenotype 179 OTOF 32494297 Zool Stud 2020 PMC7262541 10.6620/ZS.2020.59-4 0 0 0 118 Animals|*Echolocation|*Shrews|Bats|Evolution, Molecular|Dolphins|Phylogeny|Selection, Genetic|Hearing|Adaptation, Physiological 179 OTOF 32476384 Vestn. Otorinolaringol. 2020 10.17116/otorino20208502121 0 0 0 118 Auditory neuropathy|*Hearing Loss, Central|Cochlear Implantation|OTOF protein, human|Membrane Proteins|Mutation|Phenotype 179 OTOF 32265471 Sci Rep 2020 PMC7138848 10.1038/s41598-020-62879-y 0 0 0 118 Humans|Female|Pregnancy|Animals|Sheep|*Gene Editing|*Clustered Regularly Interspaced Short Palindromic Repeats|CRISPR-Cas System|*Recombinational DNA Repair|RNA, Guide|OTOF protein, human|*Membrane Proteins|Zygote|Mutations|Mutagenesis, Site-Directed|Base Sequence|Microinjection 179 OTOF 32211215 Am J Stem Cells 2020 PMC7076321 0 0 0 118 Animals|*Transcriptome|Hair Cells, Auditory|Cochlea|Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|beta Catenin|Regeneration|Gene Expression Regulation, Developmental|Cell Proliferation|Cell Transdifferentiation|Signal Transduction|Animals, Newborn 179 OTOF 32106631 Cells 2020 PMC7140416 10.3390/cells9030534 0 0 0 118 Animals|Humans|DYSF protein, human|Dysferlin|OTOF protein, human|Membrane Proteins|Muscle Proteins|Muscular Dystrophies|Calcium-Binding Proteins|*Vertebrate|Amino Acid Sequence|Mutations 179 OTOF 32048449 Mol Genet Genomic Med 2020 PMC7196461 10.1002/mgg3.1177 1 0 0 118 Humans|Nonsyndromic Deafness|*Deafness|*Asian Continental Ancestry Group|Hearing Loss, Sensorineural|Connexins|Mutations|Pedigree|High-Throughput Nucleotide Sequencing 179 OTOF 31992338 Orphanet J Rare Dis 2020 PMC6986010 10.1186/s13023-020-1311-2 1 0 0 118 Humans|*Molecular Epidemiology|*Alleles|*Mutations|Connexins|Deafness|Connexin 26|*Asian Continental Ancestry Group|Hearing Loss|Heterozygote|Hearing Loss, Sensorineural 179 OTOG 32251013 Ear Hear 2020 10.1097/AUD.0000000000000878 0 0 0 16 *Meniere Disease|Hearing Loss, Sensorineural|Tinnitus|Pedigree|Genetic Heterogeneity|Deafness 35 OTOG 32244554 Genes (Basel) 2020 PMC7230222 10.3390/genes11040379 0 0 0 16 Male|Humans|Child|*Phenotype|Exome|Homozygote|Sequencing, Whole Exome|Pedigree|Intellectual Disability|Genotype-Phenotype Correlations|Sequence Analysis, DNA|Neurodevelopmental Disorders|Gene Mapping 35 OTOG 32048449 Mol Genet Genomic Med 2020 PMC7196461 10.1002/mgg3.1177 1 0 0 16 Humans|Nonsyndromic Deafness|*Deafness|*Asian Continental Ancestry Group|Hearing Loss, Sensorineural|Connexins|Mutations|Pedigree|High-Throughput Nucleotide Sequencing 35 OTOG 31939014 Environ Sci Pollut Res Int 2020 10.1007/s11356-019-07559-9 0 0 0 16 Animals|*Livestock|*Water|Conservation of Natural Resources|Ecosystem|Grassland|Agriculture|Water Resources|China|*Water-Electrolyte Balance|*Resource Allocation 35 Ovol1 32637184 Bone Res 2020 PMC7329904 10.1038/s41413-020-0101-8 0 0 0 127 *Bone Density|Genome-Wide Association Study|Osteoporosis|*Phenotypes|Femur Neck|Genetic Pleiotropy|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease 62 Ovol1 32366868 Cell Death Dis 2020 PMC7198514 10.1038/s41419-020-2500-6 0 0 0 127 Humans|Female|Pregnancy|*Trophoblasts|HDAC1 protein, human|*Histone Deacetylase 1|Epigenesis, Genetic|*Placenta|*Cell Differentiation|Placental Development|*Progenitor Cells|Transcription Factors|Cells, Cultured|Syncytium|Histone|Gene Expression|TEAD4 protein, human|DNA-Binding Proteins|Muscle Proteins 62 Ovol1 32214018 J Clin Med 2020 PMC7141508 10.3390/jcm9030891 0 0 0 127 *Keratinocytes|*Receptors, Aryl Hydrocarbon|IL33 protein, human|*Interleukin-33|*Downregulation|Intermediate Filament Proteins|Atopic Dermatitis|*Protein Transport|Cytochrome P-450 CYP1A1|Membrane Proteins|Up-Regulation|Protein Precursors|Signal Transduction|Cells, Cultured 62 Ovol1 32106476 J Clin Med 2020 PMC7141138 10.3390/jcm9030618 0 0 0 127 Humans|*Keratosis, Actinic|*Carcinoma, Squamous Cell|*Down-Regulation|*Skin Neoplasms|Transcription Factors|Zinc Finger E-box-Binding Homeobox 1|Epithelial-Mesenchymal Transition|Upregulation|Gene Expression Regulation, Neoplastic|Immunohistochemistry|Vimentin|Disease Progression|ZEB1 protein, human|Ovol2 protein, human 62 Ovol1 32005677 Dis Model Mech 2020 PMC7104862 10.1242/dmm.042218 1 0 0 127 Animals|Transcription Factors|Zinc Finger E-box-Binding Homeobox 1|Homeodomain Proteins|Epithelial-Mesenchymal Transition|Cadherins|Cell Line, Tumor 62 Ovol1 31934116 Int J Clin Exp Pathol 2020 PMC6949574 0 0 0 127 Humans|Male|*Zinc Finger E-box-Binding Homeobox 1|*Carcinoma, Squamous Cell|*Genes, Homeobox|*Mouth Neoplasms|Transcription Factor|Homeodomain Proteins|*Neoplastic Processes|Lymphatic Metastasis|Cell Proliferation|Cell Line, Tumor|Up-Regulation|Zinc Fingers|OVOL1 protein, human|DNA-Binding Proteins 62 OVOL2 32244352 Cells 2020 PMC7226816 10.3390/cells9040840 0 0 0 96 Female|Mice|Pregnancy|Animals|*Trophoblasts|*Transcription Factor|*Placental Development|*Cell Differentiation|*Stem Cells|Placentas|Gene Expression Regulation, Developmental|Cell Line|Embryogenesis 53 OVOL2 32106476 J Clin Med 2020 PMC7141138 10.3390/jcm9030618 0 0 0 96 Humans|*Keratosis, Actinic|*Carcinoma, Squamous Cell|*Down-Regulation|*Skin Neoplasms|Transcription Factors|Zinc Finger E-box-Binding Homeobox 1|Epithelial-Mesenchymal Transition|Upregulation|Gene Expression Regulation, Neoplastic|Immunohistochemistry|Vimentin|Disease Progression|ZEB1 protein, human|Ovol2 protein, human 53 OVOL2 32005677 Dis Model Mech 2020 PMC7104862 10.1242/dmm.042218 0 0 0 96 Animals|Transcription Factors|Zinc Finger E-box-Binding Homeobox 1|Homeodomain Proteins|Epithelial-Mesenchymal Transition|Cadherins|Cell Line, Tumor 53 oxr1 32622948 Life Sci. 2020 10.1016/j.lfs.2020.118046 0 0 0 174 Rats|Animals|HCRT protein, human|*Orexins|*Phospholipase B|*Phospholipase|*Water|*Memory|*Hippocampus|Maze Learning|1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea|Benzoxazoles|Orexin Receptors|Learning, Spatial|Naphthyridines|Rats, Wistar|Urea|C3 protein, human|*Complement C3 123 oxr1 32585243 Life Sci. 2020 10.1016/j.lfs.2020.117848 0 0 0 174 Animals|*Monocrotaline|crocin|*Reactive Oxygen Species|*Pulmonary Arterial 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Biochem. 2020 10.1002/jcb.29664 0 0 0 57 Humans|Male|*Prostate|*Prostate Cancer|Antigens, Neoplasm|Cell Line, Tumor|*Cells, Epithelial|*Stromal Cell|Protein Conformation|Phosphorylation|Signal Transduction|Transcriptional Activation|Disease Progression|PAGE4 protein, human 31 PALMD 32141789 Circ Genom Precis Med 2020 10.1161/CIRCGEN.119.002617 1 0 0 58 Aortic Valve, Calcification of|Aortic Valve Stenosis|Calcinosis|Aortic Valve|Genome-Wide Association Study|*Genetic Testing|Polymorphism, Single Nucleotide|Case-Control Studies|Risk Factors 20 PARP12 32251302 Sci Rep 2020 PMC7090014 10.1038/s41598-020-61738-0 0 0 0 93 Animals|Female|Male|*Testis|*Transcriptome|*Transcriptome Analysis|Ovary|Sex Differentiation|Gonads|Sequencing, RNA|*Perciformes|High-Throughput RNA Sequencing|Sexual Maturation|Real Time Polymerase Chain Reaction|Base Sequence 20 PARP12 32105410 FEBS Open Bio 2020 PMC7137799 10.1002/2211-5463.12824 0 0 0 93 Humans|MIRN330 microRNA, human|*miRNAs|MIRN1202 microRNA, human|*Osteosarcoma|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|*Tumorigenesis|Gene Regulatory Networks|Downregulation|Gene Expression Profiling|Bone Neoplasms|Gene Ontology|Up-Regulation|Protein Interaction Maps|Signal Transduction|Computational Biology|Cell Proliferation|Prognosis 20 PARP3 32423430 BMC Cancer 2020 PMC7236215 10.1186/s12885-020-06903-4 0 0 0 178 Humans|*TRPM Cation Channels|*Leukemia, Myeloid, Acute|PARP2 protein, human|*Poly(ADP-ribose) Polymerases|PARP3 protein, human|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|Bone Marrow|Hematopoietic Stem Cells|*Cell Cycle Proteins|Bone Marrow Cells|Apoptosis|TRPM2 protein, human 80 PARP3 32383115 Adv. 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Biochem. 2020 10.1002/jcb.29635 2 0 0 0 Humans|Male|Mice|Animals|*RNA, Long Noncoding|*Prostate|*Colorectal Cancer|Cell Proliferation|MicroRNAs|Apoptosis|*Disease Progression|Gene Expression Regulation, Neoplastic|RNA Interference|Cell Movement|Cell Line, Tumor|Epithelial-Mesenchymal Transition|*Androgens|Downregulation|*Colonic Neoplasms|Tumor Burden|Prostatic Neoplasms|LRG1 protein, human 48 pax6a 32555736 PLoS Genet. 2020 PMC7323998 10.1371/journal.pgen.1008774 0 0 0 0 Animals|*Neural Crest|*Anterior Eye Segment|Anterior segment mesenchymal dysgenesis|Eye Abnormalities|Homeodomain Proteins|Lens, Crystalline|Zebrafish|SOXE Transcription Factors|Signal Transduction 32 pax7 32664530 Cells 2020 10.3390/cells9071673 0 0 0 861 Mice|Animals|myosin VI|*Myoblasts|*Myotubes|*Myosin Heavy Chains|Myogenesis|Myogenin|Cell Differentiation|Cell Fusion|Cell Communication|Transcription Factor PAX7|Actin Cytoskeleton|Focal Adhesion Kinase|Regeneration|Muscle, Skeletal|Membrane Fusion|Membrane Proteins|myomaker protein, mouse|Muscle Proteins 1626 pax7 32637444 Mol Ther Methods Clin Dev 2020 PMC7321796 10.1016/j.omtm.2020.05.022 0 0 0 861 Mice|Animals|*Prostacyclin|*Ischemia|Hindlimb|Neovascularization, Physiologic|Muscle, Skeletal|Regeneration|Regional Blood Flow|Artery, Femoral|*Peripheral Vascular Diseases|Disease Models, Animal|*Neovascularization, Pathologic|*Wound Healing|Arterial Occlusive Diseases 1626 pax7 32629302 Aquat. Toxicol. 2020 10.1016/j.aquatox.2020.105525 0 0 0 861 Animals|*Zebrafish|*Disinfection|Zebrafish Proteins|Embryo, Nonmammalian|Halogenation|Disinfectants|Melanophores|Water Purification|*Hypopigmentation|Dilution, Pigmentary|*Albinism, Oculocutaneous|*Iodides|Water Pollutants, Chemical|Gene Expression Regulation, Developmental 1626 pax7 32619494 Stem Cell Reports 2020 10.1016/j.stemcr.2020.06.004 0 0 0 861 Mice|Animals|Humans|Human Induced Pluripotent Stem Cells|Dystrophin|Duchenne Muscular Dystrophy|*Disease Models, Animal|Myoblasts|Cell Differentiation|Muscle Fibers, Skeletal|Myogenesis|*B Cells|Cells, Cultured|Cell Proliferation 1626 pax7 32615508 Domest. Anim. Endocrinol. 2020 10.1016/j.domaniend.2020.106479 0 0 0 861 Cattle|Animals|*Trenbolone Acetate|*Polyamines|Satellite Cells, Skeletal Muscle|Spermidine|Spermine|Estradiol|Ornithine Decarboxylase|Anabolic Agents|Receptor, IGF Type 1|Cell Proliferation|Insulin-Like Growth Factor I|Putrescine|mRNA|Cells, Cultured 1626 pax7 32596059 PeerJ 2020 PMC7307565 10.7717/peerj.9394 0 0 0 861 Humans|*Sarcoma, Alveolar Soft Part|*Transcriptome|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Translocation, Genetic|Oncogene Proteins, Fusion|Intracellular Signaling Peptides and Proteins|Soft Tissue Neoplasms|RNA, Messenger|*Connective Tissue 1626 pax7 32594064 Chin J Physiol 2020 10.4103/CJP.CJP_98_19 0 0 0 861 Rats|Animals|PAX7 protein, human|PAX7 Transcription Factor|Satellite Cells, Skeletal Muscle|MyoD Protein|PAX3 Transcription Factor|Muscle Development|Muscular Atrophies|Paired Box Transcription Factors|Soleus Muscle|Cell Differentiation|Gene Expression Regulation, Developmental 1626 pax7 32591430 Development 2020 10.1242/dev.185975 0 0 0 861 1626 pax7 32585982 Cells 2020 10.3390/cells9061531 0 0 0 861 Humans|*Skeletal Muscle Fibers|*Pluripotent Stem Cells|Induced Pluripotent Stem Cells|Cell Differentiation|Muscular Dystrophy, Duchenne|Muscle, Skeletal|Cells, Cultured|*Hematopoiesis|*Musculoskeletal Physiological Phenomena 1626 pax7 32556674 World J Urol 2020 10.1007/s00345-020-03289-7 0 0 0 861 NOS2 protein, human|*Nitric Oxide Synthase Type II|*Urinary Incontinence, Stress|*MAP Kinase Signaling System|p38 Mitogen-Activated Protein Kinases|*Cell Differentiation|Mitogen-Activated Protein Kinases|Signal Transduction|Nitric Oxide|*Myoblasts|Imidazoles|Pyridines 1626 pax7 32552916 Stem Cell Res Ther 2020 PMC7301568 10.1186/s13287-020-01742-3 0 0 0 861 Mice|Animals|PAX7 protein, human|*PAX7 Transcription Factor|*Myogenesis|*Mouse Embryonic Stem Cell|*Cell Differentiation|Precursor Muscle Cells|Embryonic Stem Cell|PAX3 Transcription Factor|Pluripotent Stem Cells|Paired Box Transcription Factors|Muscle Fibers, Skeletal|*Teratomas|Muscle, Skeletal|Pax7 protein, mouse 1626 pax7 32541004 Development 2020 PMC7328153 10.1242/dev.187344 0 0 0 861 Humans|*Cell Lineage|*Satellite Cell, Myogenic|PAX7 Transcription Factor|Muscle Development|MyoD Protein|Regeneration|Cell Differentiation|Muscle Fibers, Skeletal|Muscle, Skeletal|*Hematopoiesis|Gene Expression Regulation, Developmental|PAX7 protein, human 1626 pax7 32538862 J Neuromuscul Dis 2020 10.3233/JND-200497 0 0 0 861 Humans|*Human Induced Pluripotent Stem Cells|*Muscle, Skeletal|Myogenesis|PAX7 protein, human|PAX7 Transcription Factor|Cell Differentiation|MyoD Protein|Duchenne Muscular Dystrophy|Muscle Fibers, Skeletal|Stem Cell Transplantation|Regeneration|Cells, Cultured 1626 pax7 32536877 Front Physiol 2020 PMC7268892 10.3389/fphys.2020.00529 0 0 0 861 Animals|*Chickens|*Pectoralis Muscles|Poultry Diseases|Myogenesis|Satellite Cells, Skeletal Muscle|Myogenic Regulatory Factors|Muscle Fibers, Skeletal|*Collagen|Muscular Diseases|Animal Feed|*Macrophage|Stem Cells|Cell Differentiation 1626 pax7 32531778 PLoS ONE 2020 PMC7292682 10.1371/journal.pone.0219721 0 0 0 861 *Wnt1 Protein|*Neurogenesis|Frizzled Receptors|Wnt Proteins|*Cell Proliferation|Low Density Lipoprotein Receptor-Related Protein-6|beta Catenin|Wnt Signaling Pathway|Neural Tube|Neurons|Ligands|Spinal Cord 1626 pax7 32525407 Cell Transplant 2020 10.1177/0963689720923574 0 0 0 861 Humans|stage-specific embryonic antigen-3|PTPRC protein, human|*Leukocyte Common Antigens|*Stage-Specific Embryonic Antigens|*Antigens, Tumor-Associated, Carbohydrate|S1PR2 protein, human|Receptors, Lysosphingolipid|Pluripotent Stem Cells|Cell Differentiation|Mesenchymal Stem Cells 1626 pax7 32506986 Int. 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Pathol. 2020 10.1177/1066896920929081 0 0 0 861 Ewings Sarcoma|Sarcoma, Small Cell|RNA-Binding Protein EWS|Sarcoma|Soft Tissue Neoplasms|Calmodulin-Binding Proteins|Oncogene Proteins, Fusion|Translocation, Genetic|In Situ Hybridization, Fluorescence|Biomarkers, Tumor 1626 pax7 32503231 Animals (Basel) 2020 PMC7341298 10.3390/ani10060969 0 0 0 861 1626 pax7 32493438 Skelet Muscle 2020 PMC7268645 10.1186/s13395-020-00234-5 0 0 0 861 *Myosin Heavy Chain|PAX7 protein, human|PAX7 Transcription Factor|*Muscle, Skeletal|*Pluripotent Stem Cell|Myogenesis|Myoblasts|*Isoforms|Cell Differentiation|Muscle Contraction|Muscle Fibers, Skeletal|Oxidative Stress 1626 pax7 32489328 Cancer Cell Int. 2020 PMC7247181 10.1186/s12935-020-01282-z 0 0 0 861 Humans|Child|*HMGA2 Protein|*Rhabdomyosarcoma|*Oncogenesis|*Oncogenes|Rhabdomyosarcoma, Alveolar|Paired Box Transcription Factors|Rhabdomyosarcoma, Embryonal|Gene Expression Regulation, Neoplastic|Oncogene Proteins, Fusion|Cell Proliferation|Cell Differentiation|Cell Line, Tumor 1626 pca3 32661204 J. Genet. 2020 0 0 0 0 Humans|Male|Prostate Cancer|*Polymorphism, Genetic|*Promoter Regions, Genetic|Prostatic Hyperplasia|Antigens, Neoplasm|Microsatellite Repeats|Mexico 491 pca3 32630458 Biomedicines 2020 10.3390/biomedicines8060173 0 0 0 0 Humans|Male|*Prostate|*Prostate-Specific Antigen|*Hyperplasia|*Prostate Cancer|*Biopsy|Antigens, Neoplasm|Biomarkers, Tumor|ROC Curve|*Immunologic Tests 491 pca3 32539255 Int Braz J Urol 2020 10.1590/S1677-5538.IBJU.2019.0521 0 0 0 0 491 pca3 32398974 EXCLI J 2020 PMC7214775 10.17179/excli2020-1036 0 0 0 0 491 pca3 32388776 Endocr. Pathol. 2020 10.1007/s12022-020-09626-1 0 0 0 0 Male|HOTAIR long untranslated RNA, human|*Long Non-Coding RNA|*Neuroendocrine Carcinomas|Neuroendocrine Tumors|*Lung Neoplasms|Carcinoid Tumor|Immunohistochemistry|Prognosis|Biomarkers, Tumor|Pancreatic Neoplasms|Stomach Neoplasms|In Situ Hybridization|Repressor Proteins|Small Cell Lung Carcinoma 491 pca3 32388502 Urol. Int. 2020 10.1159/000506885 0 0 0 0 491 pca3 32280028 Clin Genitourin Cancer 2020 10.1016/j.clgc.2020.03.005 0 0 0 0 491 pca3 32256177 Saudi J Biol Sci 2020 PMC7105665 10.1016/j.sjbs.2020.02.003 0 0 0 0 491 pca3 32250729 J. Urol. 2020 10.1097/JU.0000000000001066 0 0 0 0 Humans|Male|*mRNA|*Prostate Cancer|*Biopsy|Prostate-Specific Antigen|Prostate|Antigens, Neoplasm|Biomarkers, Tumor|GATA2 protein, human|*GATA2 Transcription Factor|Oncogene Proteins, Fusion|*Extracellular Vesicle|Logistic Models 491 pca3 32241692 Urol. Oncol. 2020 10.1016/j.urolonc.2020.02.018 0 0 0 0 Humans|Male|Prospective Studies|kallikrein-related peptidase 3, human|Prostate Specific Antigen|*Prostate Cancer|Prostate|Kallikreins|Biopsy|Biomarkers, Tumor|Risk Assessment|Cost Effectiveness 491 pca3 32228431 Anticancer Agents Med Chem 2020 10.2174/1871520620666200331102609 0 0 0 0 Humans|Male|Rats|Animals|*Prostatitis|*Selenium|*Oestradiol|*Citrus sinensis|Prostate|Tumor Necrosis Factor-alpha|*Estrogens 491 pca3 32211453 Am J Clin Exp Urol 2020 PMC7076296 0 0 0 0 491 pca3 32162868 Clin. Lab. 2020 10.7754/Clin.Lab.2019.190714 0 0 0 0 491 pca3 32154827 Genet. Mol. Biol. 2020 PMC7198024 10.1590/1678-4685-GMB-2018-0330 0 0 0 0 491 pca3 32099679 Prostate Cancer 2020 PMC7013283 10.1155/2020/3964615 0 0 0 0 491 pca3 32077525 Prostate 2020 10.1002/pros.23964 0 0 0 0 491 pca3 32021296 Onco Targets Ther 2020 PMC6974148 10.2147/OTT.S221276 0 0 0 0 491 pca3 31993103 Int J Physiol Pathophysiol Pharmacol 2020 PMC6971503 0 0 0 0 491 pca3 31991591 Cancers (Basel) 2020 PMC7072157 10.3390/cancers12020285 0 0 0 0 491 pca3 31967522 J. Urol. 2020 10.1097/JU.0000000000000757 0 0 0 0 491 PCAT1 32529802 J Gene Med 2020 10.1002/jgm.3239 0 0 0 0 Humans|Male|*Prostatic Hyperplasia|*RNA, Long Noncoding|kallikrein-related peptidase 3, human|Prostate Specific Antigen|*Prostate Cancer|Prostate|Kallikreins|Biopsy|Tumor Markers|*RNA, Untranslated|Specificity|Retinal Nonattachment, Nonsyndromic Congenital|*Retinal Diseases|Diagnosis, Differential 57 PCAT1 32339605 Exp. Cell Res. 2020 10.1016/j.yexcr.2020.112031 0 0 0 0 *Hair Follicle|*RNA, Long Noncoding|WNT10B protein, human|*Wnt Proteins|*Proto-Oncogene Proteins|Wnt Signaling Pathway|beta Catenin|Dermis|Cell Proliferation|Cells, Cultured|MicroRNAs|Regeneration 57 PCAT1 32286142 Cell Cycle 2020 PMC7217353 10.1080/15384101.2020.1748949 0 0 0 0 Male|*Carcinoma, Renal Cell|*RNA, Long Noncoding|*Upregulation|Kidney Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Down-Regulation|*Transcriptional Activation|Cell Line, Tumor|*B-Lymphocytes|Apoptosis|Disease Progression 57 PCAT1 32220602 Exp. Mol. Pathol. 2020 10.1016/j.yexmp.2020.104429 0 0 0 0 Humans|Male|Animals|*RNA, Long Noncoding|*Oncogenes|*Oncogenesis|Gene Expression Regulation, Neoplastic|Hepatocellular Carcinoma|Cancer Biomarkers|Carcinoma, Non-Small-Cell Lung|Downregulation|Cell Proliferation|Colorectal Cancer|Carcinoma, Squamous Cell|Liver Neoplasms|Lung Neoplasms 57 PCAT1 32117633 PeerJ 2020 PMC7039120 10.7717/peerj.8600 1 0 0 0 Humans|*RNA, Long Noncoding|*Stomach Neoplasms|Genome-Wide Association Study|*Chinese|Single Nucleotide Polymorphisms|*Prognosis|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Risk Factors|RNA, Messenger|China 57 PCAT1 32114419 Front Biosci (Landmark Ed) 2020 0 0 0 0 Humans|Male|*Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Drug Resistance, Neoplasm|*Lung Neoplasms|Cisplatin|MicroRNAs|A549 Cells|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|ABCB1 protein, human|*ATP Binding Cassette Transporter, Subfamily B|Apoptosis|Upregulation|Signal Transduction|Mirn129 microRNA, human 57 PCAT1 32059012 PLoS Genet. 2020 PMC7046294 10.1371/journal.pgen.1008641 1 0 0 0 Humans|Male|*Transcriptome|Phosphatidylinositol 3-Kinases|*Prostate Cancer|European Continental Ancestry Group|African Americans|*Genomics|Prostate|PTEN protein, human|PTEN Phosphohydrolase|Polymorphism, Single Nucleotide|Asian|Biomarkers, Tumor|Mutations|Cohort Studies 57 PCAT1 31983116 J BUON 2020 0 0 0 0 Humans|*RNA, Long Noncoding|*Laryngeal Neoplasms|*Cell Migration|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Proliferation|Apoptosis|Cell Line, Tumor|Biomarkers, Tumor|Xenograft Model Antitumor Assays|MIRN210 microRNA, human 57 PCAT1 31934861 Elife 2020 PMC6959990 10.7554/eLife.51492 0 0 0 0 *Membrane Transport Proteins|ATP-Binding Cassette Transporters|*Peptides|Protein Binding|Biological Transport|Protein Multimerization|Models, Molecular|Bacterial Proteins|Adenosine Triphosphate|Hydrolysis 57 PCAT1 31934037 Int J Clin Exp Pathol 2020 PMC6949654 1 0 0 0 Humans|Female|*Carcinoma, Ovarian Epithelial|*RNA, Long Noncoding|*Ovarian Neoplasms|Apoptosis|Cell Line, Tumor|Cell Proliferation|*Oncogenes|CCND1 protein, human|Cyclin D1|Cell Cycle|*Oncogenesis|Gene Expression Regulation, Neoplastic|CDK4 protein, human|Cdk4 Protein|G0 Phase|Signal Transduction|Hepatocellular Carcinoma|Up-Regulation 57 PCAT1 31927050 Life Sci. 2020 10.1016/j.lfs.2020.117295 0 0 0 0 Humans|Female|*RNA, Long Noncoding|*Down-Regulation|CDH1 protein, human|*E Cadherin|*Antigens, CD|*Endometrial Carcinoma|Enhancer of Zeste Homolog 2 Protein|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|Vimentin|*Neoplastic Processes|*Genes, Neoplasm|Cell Line, Tumor|Up-Regulation|Oncogenesis|EZH2 protein, human 57 PCAT6 32339330 Mol. Carcinog. 2020 10.1002/mc.23199 0 0 0 0 Male|*Wnt Signaling Pathway|*Up-Regulation|*Gastrointestinal Stromal Tumors|*Peroxiredoxin V|RNA, Long Noncoding|RNA, Micro|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Movement 23 PCAT6 32308433 Onco Targets Ther 2020 PMC7152555 10.2147/OTT.S237559 0 0 0 0 Humans|Male|*RNA, Long Noncoding|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Triple Negative Breast Neoplasms|Cell Line, Tumor|Radiosensitivity|Apoptosis 23 PCAT6 32103984 Onco Targets Ther 2020 PMC7012330 10.2147/OTT.S232354 1 0 0 0 Humans|Male|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Drug Resistance, Neoplasm|*Up-Regulation|Zinc Finger E-box-Binding Homeobox 1|Gene Expression Regulation, Neoplastic|MicroRNAs|*Disease Progression|Cell Proliferation|Cell Movement|Carcinogenesis|Cell Line, Tumor|*Transcriptional Activation|Apoptosis|Signal Transduction|Cisplatin|ZEB1 protein, human|MIRN543 microRNA, human 23 PCAT6 32064636 Cell Biochem. Funct. 2020 10.1002/cbf.3510 0 0 0 0 Humans|*Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|*Cell Cycle Arrest|*Apoptosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Movement|Tumorigenesis|Disease Progression|Upregulation|Signal Transduction|Prognosis|DCAF13 protein, human|RNA-Binding Proteins 23 PCAT6 32039820 Gen. Physiol. Biophys. 2020 10.4149/gpb_2019044 0 0 0 0 Male|*RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|*Stomach Neoplasms|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|*Gastritis, Hypertrophic|Wnt Pathways|Cell Line, Tumor|Apoptosis|Viability, Cell 23 PCAT6 32020063 Br. J. Cancer 2020 PMC7109049 10.1038/s41416-020-0742-9 1 0 0 0 Humans|*RNA, Long Noncoding|Epigenesis, Genetic|*Lung Carcinoma, Non-Small-Cell|Gene Expression Regulation, Neoplastic|Repressor Proteins|Transcription Factors|Cell Proliferation|Cell Movement|Lung Neoplasms 23 PCDH19 32613771 Mol Genet Genomic Med 2020 10.1002/mgg3.1376 0 0 0 74 *Sequencing, Next-Generation|*Epilepsy|Genetic Testing|Genetic Predisposition to Disease|Mutation 151 PCDH19 32582916 Cereb. Cortex 2020 10.1093/cercor/bhaa177 0 0 0 74 Humans|Seizures|*Encephalopathy|*Magnetic Resonance Imaging|Electroencephalography|Mutation|Intellectual Disability|Cadherins|Brain|*Nervous System Malformations|PCDH19 protein, human 151 PCDH19 32425876 Front Neurol 2020 PMC7203462 10.3389/fneur.2020.00311 0 0 0 74 Male|Humans|*Epilepsy|Mutations|*Chinese|Intellectual Disability|Cadherins|PCDH19 protein, human 151 PCDH19 32366910 Transl Psychiatry 2020 PMC7198503 10.1038/s41398-020-0803-0 0 0 0 74 Humans|Male|Female|Adolescent|Autism Spectrum Disorder|*Epilepsy|Seizures|Intellectual Disability|*Clustering|Cadherins|Mutation|Cohort Studies|Genotype|Patient-Centered Care|PCDH19 protein, human 151 PCDH19 32314541 Mol Genet Genomic Med 2020 PMC7284031 10.1002/mgg3.1234 1 0 0 74 Humans|Male|Female|*Intellectual Disability|*Whole Exome Sequencing|*Mutation, Missense|*Epilepsy|*Syndrome|Seizure|Mutations|Genes, X-Linked|Phenotype|Cadherins|*Chinese|PCDH19 protein, human 151 PCDH19 32189863 Ann Indian Acad Neurol 2020 PMC7061497 10.4103/aian.AIAN_465_19 0 0 0 74 151 PCDH19 32146541 Mol. Genet. Genomics 2020 10.1007/s00438-020-01657-x 1 0 0 74 Humans|*Whole Exome Sequencing|*Epilepsy|Exome|Genetic Testing|Mutation|Genetic Predisposition to Disease|Sequencing, Next-Generation|Phenotype|Epilepsy, Generalized|Cohort Studies|PCDH19 protein, human|Cadherins|NPRL3 protein, human|GTPase-Activating Proteins 151 PCDH19 32105270 Zh Nevrol Psikhiatr Im S S Korsakova 2020 10.17116/jnevro202012001155 0 0 0 74 Humans|*Epilepsy|*Mutations|Seizures|Electroencephalography|Cadherins|*Chromosome Structures|Databases, Genetic|Russia|PCDH19 protein, human 151 PCDH19 32086284 J. Med. Genet. 2020 10.1136/jmedgenet-2019-106658 0 0 0 74 *Exome|*Focal Epilepsies|*Whole Exome Sequencing|*Epilepsies|TOR Serine-Threonine Kinases|GTPase-Activating Proteins|Mutation|Mechanistic Target of Rapamycin Complex 1|Genetic Predisposition to Disease|Tumor Suppressor Proteins|Genetic Variation|Repressor Proteins|Signal Transduction 151 PCDH19 32057594 Pediatr. 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Neurosci. 2020 PMC7117892 10.1523/JNEUROSCI.2316-19.2020 0 0 0 129 Rats|Animals|Pontocerebellar Hypoplasia Type 3|*Olivopontocerebellar Atrophies|Synapses|*Dysfunction, Cerebellar|Purkinje Cells|Axons|Synaptic Transmission|Neuropeptides|Cytoskeletal Proteins|*Phenotypes 132 PCLO 32034058 J. Clin. Pathol. 2020 10.1136/jclinpath-2019-206400 0 0 0 129 *Stomach Neoplasms|*Oncogenes|*Adenocarcinoma|Mutation|Biomarkers, Tumor|Stomach 132 PCLO 32017470 Cancer Med 2020 PMC7131865 10.1002/cam4.2903 1 0 0 129 Humans|*Carcinoma, Hepatocellular|*Hepatitis B virus|Liver Neoplasms|*Hepatitis B|*Mutation|CTNNB1 protein, human|beta Catenin|Tumor Suppressor Protein p53|Oncogenes|*Liver|Prognosis|*Virus Diseases 132 PCNP 32548978 J. Cell. Mol. Med. 2020 10.1111/jcmm.15491 1 0 0 156 Female|Humans|*Ovarian Cancer|*Carcinoma, Ovarian Epithelial|Wnt Signaling Pathway|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|*Catenins|beta Catenin|Cell Proliferation|Apoptosis|Cell Line, Tumor|*Neoplastic Processes|*Disease Progression|Neuroblastoma 59 PCNP 32406484 Rev Esp Sanid Penit 2020 PMC7307651 10.18176/resp.0002 0 0 0 156 Humans|Peru|Prisoners|Health Services Accessibility|*Hispanic Americans 59 PCP4 32641824 Lab. Invest. 2020 10.1038/s41374-020-0462-z 0 0 0 105 Humans|NeuroD protein|*Nerve Tissue Proteins|*Basic Helix-Loop-Helix Transcription Factors|*Neuroblastoma|*Neurite Outgrowth|*Downregulation|*Gene Expression Regulation|Neurons|Cell Differentiation|Apoptosis|siRNA|ASCL1 protein, human 109 PCP4 32569388 J. Bone Miner. Res. 2020 10.1002/jbmr.4120 0 0 0 105 Animals|Mice|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|Osteogenesis|Odontogenesis|Odontoblasts|Wnt Signaling Pathway|Tooth|Cell Differentiation|Tooth Root|Molars|beta Catenin|Transcription Factor|Morphogenesis|Dentin|Downregulation|Upregulation|Progenitor Cells|Pcp4 protein, mouse 109 PCP4 32199130 Mol Ther Nucleic Acids 2020 PMC7082497 10.1016/j.omtn.2019.11.038 0 0 0 105 Humans|Rats|Animals|*MAP Kinase Signaling System|*Cell Differentiation|*Osteogenesis|Osteoblasts|*Osteoporosis|MicroRNAs|Signal Transduction|Cell Proliferation|Bone Mineral Density|Downregulation|Cells, Cultured|MIRN122 microRNA, human|MIRN122 microRNA, rat 109 PCP4 32178446 Int J Mol Sci 2020 PMC7139761 10.3390/ijms21061947 0 0 0 105 Animals|Mice|*Mice, Inbred CBA|Procaterol|Cilia|Cyclic AMP|Trachea|Epithelial Cells|Calcium 109 pdia2 32639642 Biotechnol J 2020 10.1002/biot.201900562 0 0 0 61 Humans|*HEK293 Cells|Lentivirus|Retroviridae|Transduction, Genetic|Genetic Vectors|*Endoplasmic Reticulum|*Protein Processing, Post-Translational|Gene Therapy|Gene Expression|Cell Engineering|Molecular Chaperones|Apoptosis 23 PDLIM1 31986893 Neoplasma 2020 10.4149/neo_2020_190612N506 1 0 0 164 Humans|Leukocytes, Mononuclear|*Cell Proliferation|*Apoptosis|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|3' Untranslated Region|MicroRNAs|Downregulation|beta Catenin|Wnt Signaling Pathway|*Catenins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Oncogenes|Oncogenesis|MIRN370 microRNA, human 43 PDLIM1 31930728 J. 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Monit. 2020 PMC7313425 10.12659/MSM.923366 0 0 0 125 Humans|*Lung Adenocarcinoma|Adenocarcinoma|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Prognosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Bioinformatics|Downregulation|Proportional Hazards Models|PDZD2 protein, human|Neoplasm Proteins|Adaptor Proteins, Signal Transducing|MIRN21 microRNA, human 57 PDZD7 32596459 Sci Adv 2020 PMC7299630 10.1126/sciadv.aba5136 0 0 0 36 *Adenosine|*RNA|*Inosine|Editing, RNA|Adenosine Deaminase|*Neoplastic Processes|RNA-Binding Proteins|Cancers 30 PDZD7 32050993 J Transl Med 2020 PMC7014749 10.1186/s12967-020-02258-3 0 0 0 36 *Retinitis Pigmentosa|*Sequencing, Whole Genome|DNA Mutational Analysis|Pedigree|Genes, Recessive|Genetic Association Studies|High-Throughput Nucleotide Sequencing|Mutation|*Heredity|*Algorithm 30 PDZD7 32048449 Mol Genet Genomic Med 2020 PMC7196461 10.1002/mgg3.1177 1 0 0 36 Humans|Nonsyndromic Deafness|*Deafness|*Asian Continental Ancestry Group|Hearing Loss, Sensorineural|Connexins|Mutations|Pedigree|High-Throughput Nucleotide Sequencing 30 PDZD7 31914662 FASEB J. 2020 10.1096/fj.201901657RR 0 0 0 36 Mice|Animals|*Ankle|Mechanotransduction, Cellular|Usher Syndrome|Stereocilia|*Isoforms|Hair Cells, Auditory|PDZ Domain|USH2A protein, human|Extracellular Matrix Proteins|Carrier Proteins|Membrane Proteins|*Ankle Joint|Alternative Splicing|PDZD7 protein, mouse 30 PDZRN3 32358589 Mod. Pathol. 2020 10.1038/s41379-020-0545-9 0 0 0 80 *Carcinoma, Acinar Cell|Pancreatoblastoma|*Pancreatic Neoplasms|Pancreatic Carcinoma|Proto-Oncogene Proteins B-raf|Oncogene Fusions|Rearrangements, Gene|Mutations|Gene Fusions|Acinar Cell|Soft Tissue Neoplasms 26 PDZRN3 31980707 Sci Rep 2020 PMC6981127 10.1038/s41598-020-58116-1 0 0 0 80 Animals|Mice|*Cyclin A2|*Myoblasts|*Apoptosis|RBX1 protein, human|Carrier Proteins|Phosphorylation|Cell Differentiation|*Protective Agents|Ubiquitin-Protein Ligases|Cell Proliferation|RNA Interference|Cell Line|CASP3 protein, human|Caspase 3|PDZRN3 protein, mouse 26 pedf 32666268 Angiogenesis 2020 10.1007/s10456-020-09735-9 0 0 0 1508 Humans|Child|FG-4592|Vascular Endothelial Growth Factor A|*Isoquinolines|vadadustat|*Glycine|*Lung|Congenital Diaphragmatic Hernia|Prolyl-Hydroxylase Inhibitors|Pneumonectomy|Vascular Endothelial Growth Factors|*Organogenesis|Factor, Angiogenic|Anemia|Neovascularization, Pathologic|Picolinic Acids 1357 pedf 32635833 Tissue Eng Part C Methods 2020 10.1089/ten.TEC.2020.0072 0 0 0 1508 Animals|Humans|*Retinal Pigment Epithelium|*Nanofibers|*Induced Pluripotent Stem Cells|*Soybean Proteins|Bruch's Membrane|polycaprolactone|Polyesters|Age Related Macular Degeneration|Tissue Scaffolds|Cell Differentiation|TYRP1 protein, human|*Membrane Glycoproteins 1357 pedf 32585760 Wound Repair Regen 2020 10.1111/wrr.12828 0 0 0 1508 Rabbits|Animals|pigment epithelium-derived factor|*Cicatrix, Hypertrophic|*Serpins|*Nerve Growth Factors|*Eye Proteins|*Collagen|Wound Healing|Ear|Skin|*Neovascularization, Pathologic|Intradermal Injection|Antiangiogenic Agents|*Morphogenesis|mRNA 1357 pedf 32567146 Lasers Surg Med 2020 10.1002/lsm.23288 0 0 0 1508 *Retinal Pigment Epithelium|*Choroid|Age Related Macular Degeneration|Serpins|Nerve Growth Factors|Eye Proteins|Bruch's Membrane|Vascular Endothelial Growth Factor A|Cells, Cultured 1357 pedf 32560932 J Affect Disord 2020 10.1016/j.jad.2020.04.013 0 0 0 1508 Humans|*Vascular Endothelial Growth Factor A|*Vascular Endothelial Growth Factor B|*Ketamine|Serpins|Nerve Growth Factors|Eye Proteins|mRNA|Cells, Cultured 1357 pedf 32544239 Hum. Reprod. 2020 10.1093/humrep/deaa118 0 0 0 1508 Pregnancy|Female|Humans|pigment epithelium-derived factor|*Natural Killer Cells|Decidua|*Serpins|*Nerve Growth Factors|*Eye Proteins|*Cells, Stromal|Trophoblasts|*Inflammation|Signal Transduction|Cells, Cultured|*Cell Death|Coculture Techniques|*Protective Agents 1357 pedf 32532667 Reprod. Biomed. Online 2020 10.1016/j.rbmo.2020.03.024 0 0 0 1508 Animals|pigment epithelium-derived factor|*Serpins|*Nerve Growth Factors|*Eye Proteins|*Uterine Fibroids|Vascular Endothelial Growth Factor A|Cell Line, Tumor|Disease Models, Animal 1357 pedf 32529845 Biomarkers 2020 10.1080/1354750X.2020.1774654 0 0 0 1508 1357 pedf 32455741 Int J Mol Sci 2020 PMC7279371 10.3390/ijms21103635 0 0 0 1508 Humans|Vascular Endothelial Growth Factor A|Endothelial Cells|Age Related Macular Degeneration|Retinal Pigment Epithelium|*Pathological Angiogenesis|Serpins|Nerve Growth Factors|Eye Proteins|*Morphogenesis|Vascular Endothelial Growth Factors|Cells, Cultured|Angiogenesis Inhibitors|Cytokines|*Neurons|Cell Differentiation|Iron|Retinal Pigments 1357 pedf 32427349 J. Comp. Neurol. 2020 10.1002/cne.24940 0 0 0 1508 Humans|Animals|Mice|pigment epithelium-derived factor|pigment epithelium-derived factor receptor|*Serpins|*Nerve Growth Factors|*Eye Proteins|*Receptors, Neuropeptide|Retina|Western Blotting|Immunohistochemistry|Cerebellum|Enzyme-Linked Immunosorbent Assay 1357 pedf 32407187 Ocul. Immunol. Inflamm. 2020 10.1080/09273948.2020.1751211 0 0 0 1508 1357 pedf 32387568 Ocul Surf 2020 PMC7322788 10.1016/j.jtos.2020.05.002 0 0 0 1508 Mice|Animals|pigment epithelium-derived factor|*Serpins|*Nerve Growth Factors|*Eye Proteins|*Dry Eye Disease|*Epithelial Cells|Disease Models, Animal|*Cell Differentiation|Dendritic Cells 1357 pedf 32385771 Mol. Biol. Rep. 2020 10.1007/s11033-020-05496-2 0 0 0 1508 Humans|Female|Mice|Animals|pigment epithelium-derived factor|Diabetes Mellitus, Experimental|PGF protein, human|Placenta Growth Factor|*Serpins|*Nerve Growth Factors|*Eye Proteins|Retinal Neovascularization|Retina|Diabetic Retinopathy|Neovascularization, Pathologic|Vascular Endothelial Growth Factor A|Angiogenesis Inhibitors|Human Umbilical Vein Endothelial Cells|silencer factor B|*Eutheria 1357 pedf 32385162 Proc. Natl. Acad. Sci. 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Med. 2020 10.1016/j.ejim.2020.05.032 0 0 0 3064 Humans|Animals|*Vitamin|*Anticoagulant|Vitamin K|Warfarin|Venous Thromboembolism|Atrial Fibrillation|Administration, Oral|Bleeding|*Bone|*Cardiovascular System 1579 periostin 32518264 Sci Rep 2020 PMC7283227 10.1038/s41598-020-66278-1 0 0 0 3064 Humans|Mice|Animals|*Tenascin|Endothelial Cells|*Retinal Neovascularization|*Vitreoretinopathy, Proliferative|Diabetic Retinopathy|POSTN protein, human|*Cell Adhesion Molecules|Vitreous Humor|Retina|neuronectin|*Extracellular Matrix Proteins|*Neovascularization, Pathologic|*Nerve Tissue Proteins|Retinal Vessels|Retinal Diseases|Retinal Vein Occlusion|Vascular Endothelial Growth Factor A|Cell Movement 1579 periostin 32517742 Respir. Res. 2020 PMC7285606 10.1186/s12931-020-01413-0 0 0 0 3064 Humans|*Albuminuria|*Sleep Apnea, Obstructive|Continuous Positive Airway Pressure|Polysomnography|Body Mass Index|Obesity|Overweight|POSTN protein, human|*Cell Adhesion Molecules|Hypoxia|Severity of Illness Index 1579 PGAP3 32084330 Am. J. Hum. 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Monit. 2020 PMC7063849 10.12659/MSM.919251 0 0 0 0 Female|Mice|Animals|*Platelet-Derived Growth Factor|*Menstruation|*Endometrium|Cell Proliferation|Stromal Cells|Cells, Cultured|Signal Transduction|*Peripheral Blood Stem Cells|Re-Epithelialization 49 pgm5 32438913 BMC Med 2020 PMC7243334 10.1186/s12916-020-01605-x 0 0 0 35 Infant, Newborn|Humans|Female|Pregnancy|*Stillbirth|*mRNA|*Placental Insufficiency|Fetal Growth Restriction|Infant, Small for Gestational Age|Placenta 38 pgm5 32412676 Mol Oncol 2020 10.1002/1878-0261.12711 0 0 0 35 Mice|Animals|*RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|*Fibrillin-1|Mice, Nude|*Osteosarcoma|MicroRNAs|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Tumorigenesis|Cell Movement|Cell Proliferation|Cell Line, Tumor|Upregulation|Disease Progression|shRNA|Bone Neoplasms 38 pgm5 32354224 Cancer Biother. Radiopharm. 2020 10.1089/cbr.2019.3059 0 0 0 35 38 pgm5 32221390 Sci Rep 2020 PMC7101342 10.1038/s41598-020-62548-0 0 0 0 35 Animals|Humans|*Phosphoglucomutase|Glycogen Storage Disease XIV|Disease, Glycogen Storage|*Mannose-6-Phosphate Isomerase|*Glucose-6-Phosphate Isomerase|Mutations, Missense|Mutations|Catalytic Domain|Phenotype|*Isoforms|Glycosylation|Ligands|glucose-1-phosphate|Glucosephosphates 38 pgm5 32176636 Cancer Biomark 2020 10.3233/CBM-192389 0 0 0 35 *Long Non-Coding RNA|*Stomach Neoplasms|*Adenocarcinoma|Gene Regulatory Networks|RNA, Messenger|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|MicroRNAs|Computational Biology 38 pgm5 31921195 Front Immunol 2020 PMC6930242 10.3389/fimmu.2019.02948 1 0 0 35 38 PHACTR1 32420588 Biosci. Rep. 2020 PMC7276519 10.1042/BSR20193779 0 0 0 73 Humans|Genome-Wide Association Study|*Actin|*Blood Pressure|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Allele|Haplotypes|Genetic Association Studies|Genotype|Case-Control Studies|Microfilament Proteins|Odds Ratio|*Regulator Gene|*Phosphoric Monoester Hydrolases 75 PHACTR1 32411507 PeerJ 2020 PMC7207206 10.7717/peerj.8841 0 0 0 73 Humans|Moyamoya disease 1|*Moyamoya Disease|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Adenosine Triphosphatases|Ubiquitin-Protein Ligases|*Disease Progression|Case-Control Studies|Far East 75 PHACTR1 32374345 JAMA Cardiol 2020 PMC7203673 10.1001/jamacardio.2020.0872 0 0 0 73 75 PHACTR1 32046629 J Headache Pain 2020 PMC7011260 10.1186/s10194-020-01087-5 0 0 0 73 75 PHACTR1 31980275 J Clin Neurosci 2020 10.1016/j.jocn.2020.01.018 0 0 0 73 *Actin|*Plaque, Atherosclerotic|*Carotid Artery|Carotid Atherosclerosis|*Carotid Artery, Common|Atherosclerosis|Coronary Artery Disease|Microfilament Proteins|Genetic Predisposition to Disease|Muscle, Smooth, Vascular|Endothelin-1|*Phosphoric Monoester Hydrolases 75 PHACTR1 31972008 Eur. 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Signal. 2020 PMC7137739 10.1016/j.cellsig.2020.109554 0 0 0 62 Humans|*Receptors, Erythropoietin|JAK2 protein, human|*Janus Kinase 2|*Phosphatases|*Proteomics|EPO protein, human|*Erythropoietin|*Signal Transduction|STAT5A protein, human|Signal Transducer and Activator of Transcription 5A|*Protein Processing, Post-Translational|Phosphorylation|Erythroid Progenitor Cells|Erythropoiesis|Myeloproliferative Disorders|SH3 Domain|Adaptor Proteins, Signal Transducing|DNA-Binding Proteins 42 PI15 32645918 J Clin Med 2020 10.3390/jcm9072139 0 0 0 30 Carotid Intima-Media Thickness|*Prediabetic State|Prospective Studies|*Carotid Atherosclerosis|Plaque, Atherosclerotic|Atherosclerosis|Carotid Arteries|Risk Factors|Cross-Sectional Studies|Cardiovascular Diseases|Cohort Studies 389 PI15 32645888 Genes (Basel) 2020 10.3390/genes11070757 0 0 0 30 *Myotonic Dystrophy|*Thymine|*Cytosine|*Guanine|Myotonin-Protein Kinase|Trinucleotide Repeat Expansion|Trinucleotide Repeats|Polymerase Chain Reaction 389 PI15 32640991 BMC Fam Pract 2020 10.1186/s12875-020-01207-9 0 0 0 30 Humans|*Secondary Care|*Cross-Sectional Studies|Spain|*Physicians|Primary Healthcare|*Government Programs|Continuity of Patient Care|Healthcare|Qualitative Research|Surveys and Questionnaires|*Research Personnel|*Medical Assistance 389 PI15 32635473 Cancers (Basel) 2020 10.3390/cancers12071790 0 0 0 30 Humans|Mice|Animals|Neoplasm Recurrence, Local|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|*Cancer Stem Cells|*Pancreas|Xenograft Model Antitumor Assays|*Lysosomes|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction|Disease Models, Animal 389 PI15 32607644 J. Neurol. 2020 10.1007/s00415-020-10018-y 0 0 0 30 carbidopa, levodopa drug combination|*Levodopa|*Parkinson Disease|*Double-Blind Method|Carbidopa|Antiparkinson Agents|Administration, Oral|Drug Combinations|Gels|Cognition 389 PI15 32605302 Diagnostics (Basel) 2020 10.3390/diagnostics10070437 0 0 0 30 Humans|*Methylation|*Colorectal Cancer|Occult Blood|Early Detection of Cancer|Colonoscopy|Adenoma|Specificity|CpG Island|NEUROG1 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Biomarkers, Tumor|Feces|*Nerve Tissue Proteins|*Colonic Neoplasms|Promoter Regions, Genetic|Case-Control Studies|Cohort Studies 389 PI15 32575903 Cancers (Basel) 2020 10.3390/cancers12061644 0 0 0 30 Humans|*Bile|Pancreatic Carcinoma|Pancreatic Neoplasms|*Constriction, Pathologic|Adenocarcinoma|Proteomics|*Cholestasis|Cholangiocarcinoma|Bile Duct Neoplasms|Biomarkers, Tumor|ROC Curve|Bile Ducts, Intrahepatic|*Machine Learning 389 PI15 32560448 Int J Environ Res Public Health 2020 PMC7344565 10.3390/ijerph17124334 0 0 0 30 Adult|Humans|Female|Male|*Adiposity|*Glycogen Storage Disease Type V|*Obesity|Body Mass Index|Absorptiometry, Dual Energy X Ray|*Lifestyle|Anthropometry|Body Fat|Physical Activity|*Sex Differences 389 PI15 32545680 Cancers (Basel) 2020 10.3390/cancers12061563 0 0 0 30 Humans|Female|Mice|Animals|*Transfection|fragile histidine triad protein|*Acid Anhydride Hydrolases|MHC Class I Molecules|*Neoplasm Proteins|Histocompatibility Antigens Class II|Genes, MHC Class I|Cytotoxic T-Lymphocytes|Antigens, Neoplasm|Immunotherapy|Neoplasm Transplantation|Tumor Cell Lines|Interferon-gamma 389 PI15 32535887 Eur. 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Med. 2020 10.1142/S0192415X20500603 0 0 0 0 Humans|*Tamoxifen|*Luteolin|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|*Apoptosis|Signal Transduction|Antineoplastic Agents, Hormonal|Receptors, Estrogen|Drug Resistance, Neoplasm|Cell Proliferation|Cell Line, Tumor 3811 PI3K/Akt/mTOR 32665551 Nat Commun 2020 10.1038/s41467-020-17064-0 0 0 0 0 Mice|Animals|Phosphatidylinositol 3-Kinases|Transcription Factors|*B-Lymphocytes|PRDM1 protein, human|Positive Regulatory Domain I-Binding Factor 1|Gene Expression Regulation|Repressor Proteins|Gene Expression|MTOR protein, human|TOR Serine-Threonine Kinases 3811 PI3K/Akt/mTOR 32660056 Diagnostics (Basel) 2020 10.3390/diagnostics10070467 0 0 0 0 Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi|Phosphatidylinositol 3-Kinases|*Musculoskeletal Abnormalities|*Nevus|*Vascular Malformations|*Lipoma|Class I Phosphatidylinositol 3-Kinases|MTOR protein, human|TOR Serine-Threonine Kinases|Phenotype|Signal Transduction|Growth Disorders|Mutation|*Rheumatoid Arthritis 3811 PI3K/Akt/mTOR 32659083 J. 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Chem. 2020 10.1021/acs.jmedchem.0c00696 0 0 0 0 *fms-Like Tyrosine Kinase 3|*fms-Like Tyrosine Kinase|Phosphatidylinositol 3-Kinases|*Leukemia, Myeloid, Acute|Protein Kinase Inhibitors|Signal Transduction|Mutation 3811 PI3K/Akt/mTOR 32656203 Front Cell Dev Biol 2020 PMC7325939 10.3389/fcell.2020.00383 0 0 0 0 Animals|Female|Lactation|Mammary Glands, Animal|Goats|Milk|miRNAs|Casein|Epithelial Cells|Triglycerides|*Organogenesis 3811 PI3K/Akt/mTOR 32655800 Am J Transl Res 2020 PMC7344056 0 0 0 0 Rats|Animals|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Ezetimibe|*Autophagy|*Injury, Spinal Cord|MTOR protein, human|*TOR Serine-Threonine Kinases|*Apoptosis|*Signal Transduction|CASP3 protein, human|Caspase 3|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Spinal Cord|CASP9 protein, human|Caspase 9|Beclin1|Recovery of Function 3811 PI3K/Akt/mTOR 32655659 Evid Based Complement Alternat Med 2020 PMC7327581 10.1155/2020/4121483 0 0 0 0 Mice|Animals|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|Cell Proliferation|Apoptosis|*Small Cell Lung Carcinoma|Autophagy|Cancer of Lung|Xenograft Model Antitumor Assays|Rapamycin|Analgesics 3811 PI3K/Akt/mTOR 32296030 Signal Transduct Target Ther 2020 PMC7005297 10.1038/s41392-020-0110-5 0 0 0 0 Phosphatidylinositol 3-Kinases|*Cancer|Cancer Stem Cells|Signal Transduction|NF-kappa B|Gene Expression Regulation, Neoplastic|*B-Lymphocytes|Phosphoinositide 3 Kinase|Cancer-Associated Fibroblasts|Janus Kinases|Cell Differentiation|Transcription Factors 3811 PI3K/Akt/mTOR 32654229 J. Cell. Physiol. 2020 10.1002/jcp.29926 0 0 0 0 Humans|Phosphatidylinositol 3-Kinases|*Glioma|*Oncogenesis|*Oncogenes|Cell Proliferation|Brain Neoplasms|MTOR protein, human|TOR Serine-Threonine Kinases|Proto-Oncogene Proteins c-akt|Cell Movement|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|MicroRNAs|Phosphopyruvate Hydratase|Phosphoric Monoester Hydrolases 3811 PI3K/Akt/mTOR 32653371 Int. J. Biol. Macromol. 2020 10.1016/j.ijbiomac.2020.07.069 0 0 0 0 Humans|laminaran|*Lung Cancer|*Glucans|Proto-Oncogene Proteins c-akt|Cell, A549|TOR Serine-Threonine Kinases|Cell Proliferation|Signal Transduction|Apoptosis|Cell Line, Tumor|Sargassum 3811 PI3K/Akt/mTOR 32651704 Biotechnol. 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Med. 2020 10.1111/jcmm.15475 0 0 0 0 Mice|Animals|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Particulate Matter|IL17A protein, human|*Interleukin-17|MTOR protein, human|*TOR Serine-Threonine Kinases|*Autophagy|*Lung Inflammation|Signal Transduction|Pulmonary Fibrosis|Up-Regulation|Cells, Epithelial|*Fibrosis 3811 PI3K/Akt/mTOR 32638014 Acta Biochim. Biophys. Sin. 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Anat. 2020 10.1016/j.aanat.2019.151456 0 0 0 115 Animals|Humans|*Nipples|Pacinian Corpuscles|Mechanoreceptors|Skin|Merkel Cells|Epidermis|*Musculoskeletal Physiological Phenomena|*Nervous System Physiological Phenomena|Aging 186 PILRA 32296418 Front Immunol 2020 PMC7137904 10.3389/fimmu.2020.00456 0 0 0 23 *Alzheimer Disease|Genome-Wide Association Study|*Precision Medicine|tau Proteins|Amyloid beta-Peptides|Microglia 38 PILRA 32008055 J. Mol. Med. 2020 PMC7080693 10.1007/s00109-020-01875-1 0 0 0 23 Pregnancy|Male|Female|Humans|Infant, Newborn|Rats|Animals|*Fetal Growth Retardation|*Infant, Small for Gestational Age|Low Protein Diet|Uterus|Animals, Newborn|Kidney|Ligation|Kidney Diseases|*Organogenesis|LTB4R2 protein, human|Receptors, Leukotriene B4|PILRA protein, human|Membrane Glycoproteins|Receptors, Immunologic|Nupr1 protein, rat|Neoplasm Proteins|Basic Helix-Loop-Helix Transcription Factors 38 PIM2 32641749 Cell Death Dis 2020 PMC7343807 10.1038/s41419-020-2700-0 0 0 0 477 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Neoplasm Recurrence, Local|*Signal Transduction|*Tumorigenesis|NF-kappa B|Cell Proliferation|*Disease Progression|Serine Threonine Kinase|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|proto-oncogene proteins pim|Proto-Oncogene Proteins c-pim-1|Cell Motility|Neovascularization, Pathologic|Upregulation|Transcriptional Activation|Phosphorylation 333 PIM2 32585145 Cryobiology 2020 10.1016/j.cryobiol.2020.05.014 0 0 0 477 *Cryopreservation|Cryoprotective Agents|Dimethylsulphoxide|*Adipocytes|*Cells, Stromal|*Adiposity|Freezing|Mesenchymal Stromal Cells|Adipose Tissue|*Obesity|Cell Differentiation|Cell Survival|Umbilical Cord|Cells, Cultured 333 PIM2 32413252 Rev Med Inst Mex Seguro Soc 2020 0 0 0 477 Child|Humans|Mexico|*Pediatric Intensive Care Units|Child Mortality|Hospital Mortality|Prospective Studies|*Standardization|ROC Curve|*Environment|PIM2 protein, human|Proto-Oncogene Proteins|Protein-Serine-Threonine Kinases 333 PIM2 32322463 Acta Pharm Sin B 2020 PMC7161711 10.1016/j.apsb.2019.10.003 0 0 0 477 Humans|AKT1 protein, human|*Protein Kinase B|*Autophagy|Lysosomes|Signal Transduction|Phosphorylation|HeLa Cells|HEK293 Cells|Autophagy-Related Proteins 333 PIM2 32278589 Arch Pediatr 2020 10.1016/j.arcped.2020.03.004 0 0 0 477 Child|Humans|*Organ Dysfunction Scores|*Lactate|*Critical Illness|*Pilot Projects|Intensive Care Units, Pediatric|Hospital Mortality|Prospective Studies|Prognosis|Severity of Illness Index|ROC Curve|*Plasma 333 PIM2 32273474 Haematologica 2020 10.3324/haematol.2019.234476 0 0 0 477 Animals|Mice|*Multiple Myeloma|TNFSF11 protein, human|RANK Ligand|TGFB1 protein, human|*Transforming Growth Factor beta1|Bone Marrow Cells|Osteoclasts|Bone Marrow|*Osteolysis|Receptor Activator of Nuclear Factor-kappa B|Cell Differentiation|Osteoclastogenesis|Stromal Cells|Tumor Necrosis Factor-alpha|Cocultures|Signal Transduction|MAPK, p38|Tumor Microenvironment 333 PIM2 32239292 Eur. J. Pediatr. 2020 10.1007/s00431-020-03639-y 0 0 0 477 Child|Humans|Switzerland|Intensive Care Units, Pediatric|Hospital Mortality|Child Mortality|Length of Stay|ROC Curve|Cohort Studies|Prospective Studies|Hospitalization|Risk Assessment|Severity of Illness Index 333 PIM2 32215894 Appl Clin Inform 2020 PMC7096317 10.1055/s-0040-1705108 0 0 0 477 Humans|Child|*Electronic Health Records|*Censuses|*Intensive Care Units, Pediatric|Documentation|Physicians|Internship and Residency|*Hospitalization|Time Factors 333 PIM2 32117120 Front Microbiol 2020 PMC7029740 10.3389/fmicb.2020.00090 0 0 0 477 333 PIM2 32000799 J Transl Med 2020 PMC6993458 10.1186/s12967-020-02220-3 0 0 0 477 Humans|*Crohn Disease|*Mesentery|*Biomarkers|*Signal Transduction|*Adipose Tissue|Intestinal Mucosa|Intestines|Case-Control Studies|*Plasma 333 PIM2 31894300 Int. J. Oncol. 2020 PMC6959465 10.3892/ijo.2019.4936 0 0 0 477 Mice|Animals|*Cell Proliferation|*Liver Cancer|Carcinoma, Hepatocellular|Apoptosis|siRNA|HepG2 Cells|Protein-Serine-Threonine Kinases|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Cycle|Signal Transduction|*M Phase|G1 Phase|Oncogenesis|Polyethylenimine|Downregulation 333 PIM3 32576196 J. Biomed. Sci. 2020 PMC7310457 10.1186/s12929-020-00668-5 0 0 0 271 *Phosphorylation|*Proto-Oncogene Proteins c-akt|*Autophagosomes|Signal Transduction|*Lung Cancer|Phosphatidylinositol 3-Kinases|TYRP1 protein, human|*Membrane Glycoproteins|Insulin Receptor Substrate Proteins|TOR Serine-Threonine Kinases|*Biological Transport|*Carbohydrate Metabolism|Glucose 172 PIM3 32504181 Endocr. Pathol. 2020 10.1007/s12022-020-09629-y 0 0 0 271 Humans|Pilot Projects|*Neuroendocrine Tumors|Carcinoid Tumor|Small Cell Lung Carcinoma|Carcinoma, Large Cell|Immunohistochemistry|Carcinoma, Neuroendocrine|Lung Neoplasms|Biomarkers, Tumor|*Bronchi|mRNA|*Phenotype|PIM1 protein, human|Proto-Oncogene Proteins c-pim-1|NEK2 protein, human|NIMA-Related Kinases 172 PIM3 32245399 BMC Genomics 2020 PMC7126399 10.1186/s12864-020-6658-1 0 0 0 271 Animals|*Chromosome Mapping|Quantitative Trait Loci|*Phenotype|Genetic Linkage|Genotype|Sequence Analysis, DNA|Polymorphism, Single Nucleotide|Aquiculture|China 172 PIM3 32088906 Cell Stress Chaperones 2020 PMC7058781 10.1007/s12192-020-01070-8 0 0 0 271 Humans|Rats|Animals|*Computational Biology|*Transcription Factors|*Stomach Ulcer|*Transcriptome|Regulatory Network, Gene|Gene Ontology|Protein Interaction Maps|Gene Expression Profiling|*Biomarkers|Software|Sequencing, RNA|Gene Expression Regulation, Neoplastic|Signal Transduction 172 PIM3 32066817 Sci Rep 2020 PMC7026418 10.1038/s41598-020-59074-4 2 0 0 271 Humans|*Poly(ADP-ribose) Polymerase Inhibitors|*Polypharmacology|rucaparib|Indoles|Poly(ADP-ribose) Polymerases|Protein Kinases|Cancer 172 PIM3 31994402 J. Proteome Res. 2020 10.1021/acs.jproteome.9b00821 0 0 0 271 *Serine Threonine Kinase|*Signal Transduction|*Cell Migration|RHOA protein, human|rhoA GTP-Binding Protein|*Proto-Oncogenes|Proto-Oncogene Proteins|Phosphorylation|Cell Line|Proteome|Serine 172 PIN4 32142471 Biol. Chem. 2020 10.1515/hsz-2019-0423 0 0 0 144 Humans|Animals|*Diazomethane|*Actins|*Polymerization|PIN4 protein, human|*NIMA-Interacting Peptidylprolyl Isomerase|Parvulin-14|cis-trans-Isomerase, Peptidyl-Prolyl|Amino Acid Sequence|Hominidae|Mitochondria|Cell Nucleus|Protein Isoforms|HeLa Cells|Protein Transport 96 PIWIL3 32486081 Cells 2020 PMC7349845 10.3390/cells9061356 0 0 0 21 Humans|Male|Mice|Rats|Animals|*Oocytes|Germ Cells|Argonaute Proteins|Testis|*Mammals|Spermatogenesis|RNA, Small Interfering 24 PIWIL3 32357464 J Clin Med 2020 PMC7287605 10.3390/jcm9051252 0 0 0 21 Humans|Male|Argonaute Proteins|*Pancreatic Cancer|Testis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|RNA, Messenger|PIWIL2 protein, human|PIWIL4 protein, human 24 pkd1l1 32111882 Sci Rep 2020 PMC7048929 10.1038/s41598-020-60589-z 1 0 0 17 *Situs Inversus|Kartagener Syndrome|Cilia|Mutations|Functional Laterality|Brain|Base Sequence 20 PKHD1 32672359 J. Clin. Lab. Anal. 2020 10.1002/jcla.23450 0 0 0 188 *Lung Adenocarcinoma|*Prognosis|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Databases, Genetic|Computational Biology|Biomarkers, Tumor|Lung Neoplasms 1120 PKHD1 32659844 Klin Padiatr 2020 10.1055/a-1179-0728 0 0 0 188 Infant, Newborn|Female|Pregnancy|Child|Humans|ADPKD|Autosomal Recessive Polycystic Kidney Disease|*Kidney Neoplasms|Kidney|*Consensus|Tuberous Sclerosis Complex|Bardet-Biedl Syndrome|Diagnostic Ultrasound|Genetic Testing|*Cysts|*Societies, Medical|Magnetic Resonance Imaging|Renal Replacement Therapy|Unilateral Multicystic Dysplastic Kidney|Nephrectomy 1120 PKHD1 32595772 Eur Endocrinol 2020 PMC7308104 10.17925/EE.2020.16.1.66 0 0 0 188 Phosphotransferases (Phosphomutases)|*Congenital Hyperinsulinism|Congenital Disorders of Glycosylation|*Disease, Polycystic Kidney|Phenotype|Mutation 1120 PKHD1 32574212 PLoS ONE 2020 PMC7310724 10.1371/journal.pone.0235071 0 0 0 188 Child|Humans|*Sequencing, Next-Generation|Autosomal Recessive Polycystic Kidney Disease|Mutation|Phenotype|Genes, Regulator|NPHP1 protein, human|Membrane Proteins|Adaptor Proteins, Signal Transducing 1120 PKHD1 32507635 J. Pediatr. Surg. 2020 10.1016/j.jpedsurg.2020.03.023 0 0 0 188 Humans|Infant, Newborn|*Polycystic Kidney, Autosomal Recessive|*Nephrectomy|Polycystic Kidney, Autosomal Dominant|Laparoscopy|Dialysis, Peritoneal|Failure, Renal 1120 PKHD1 32481435 Medicine (Baltimore) 2020 10.1097/MD.0000000000020413 0 0 0 188 Humans|*Polycystic Kidney, Autosomal Recessive|*Whole Exome Sequencing|*Chinese|Heterozygote|Mutation|Mutation, Missense|Receptors, Cell Surface 1120 PKHD1 32475690 Semin. Cell Dev. Biol. 2020 10.1016/j.semcdb.2020.05.003 0 0 0 188 Humans|Adult|Child|*Cilia|polycystic kidney disease 2 protein|TRPP Cation Channels|Potter Type III Polycystic Kidney Disease|Autosomal Recessive Polycystic Kidney Disease|Polycystic Kidney, Autosomal Dominant|Kidney Tubules|Genes, Regulator|Signal Transduction|Basal Body|Protein Transport 1120 PKHD1 32457805 Front Genet 2020 PMC7224062 10.3389/fgene.2020.00464 0 0 0 188 1120 PKHD1 32398770 Genet. Med. 2020 10.1038/s41436-020-0816-3 0 0 0 188 *Polycystic Kidney, Autosomal Dominant|TRPP Cation Channels|DNA Mutational Analysis|Mutation|*Phenotype 1120 PKHD1 32384486 Medicine (Baltimore) 2020 10.1097/MD.0000000000020113 0 0 0 188 Infant, Newborn|Humans|Child|*Polycystic Kidney, Autosomal Recessive|*Fatal Outcome|*Mutations|DNA Mutational Analysis|Potter Type III Polycystic Kidney Disease|Phenotype|Genotype|Genetic Testing|Mutations, Missense|Receptors, Cell Surface|PKHD1 protein, human 1120 PKHD1 32337892 Folia Med (Plovdiv) 2020 10.3897/folmed.62.e48003 0 0 0 188 Humans|Male|Middle Aged|Dermatofibrosarcoma|Fibrosarcoma|Immunohistochemistry|Skin Neoplasms|Soft Tissue Neoplasms|*Mutations|Antigens, CD34 1120 PKHD1 32325183 Cell. Signal. 2020 10.1016/j.cellsig.2020.109647 0 0 0 188 Humans|Animals|Polycystic Kidney, Autosomal Dominant|Polycystic Kidney, Autosomal Recessive|Kidney|*Chemokines|*Adaptive Immunity|Cytokines|Macrophages 1120 PKHD1 32311505 Cell. Signal. 2020 PMC7269823 10.1016/j.cellsig.2020.109646 0 0 0 188 Humans|*Integrins|*Focal Adhesions|*Disease, Polycystic Kidney|Polycystic Kidney, Autosomal Dominant|*Extracellular Matrix|kalinin|Cell Adhesion Molecules|*Signal Transduction|Kidney|Laminin|Fibrosis|Cells, Epithelial|Basement Membrane|*Cell Adhesion|Cell Proliferation|Gene Expression|Collagen 1120 PKHD1 32283547 Pediatr. Res. 2020 10.1038/s41390-020-0883-9 0 0 0 188 Humans|Mice|Animals|*Polycystic Kidney, Autosomal Recessive|Kidney|*Multiparametric Magnetic Resonance Imaging|*Disease Models, Animal|Disease Progression 1120 PKHD1 32231761 World J Hepatol 2020 PMC7097502 10.4254/wjh.v12.i3.72 1 0 0 188 Humans|Polycystic liver disease|*Liver Diseases|*Cysts|Polycystic Kidney, Autosomal Dominant|Liver Transplantation|Somatostatin|Liver|Embolization, Therapeutic|Ursodeoxycholic Acid|Autosomal Recessive Polycystic Kidney Disease 1120 PKHD1 32203225 Genet. Med. 2020 PMC7272321 10.1038/s41436-020-0772-y 0 0 0 188 Humans|*Kidney|Polycystic Kidney, Autosomal Dominant|Genetic Testing|Kidney Transplantation|Genetic Counseling 1120 PKHD1 32128974 Pediatr Transplant 2020 10.1111/petr.13690 0 0 0 188 Child|Humans|Infant|Child, Preschool|Adolescent|*Polycystic Kidney, Autosomal Recessive|*End Stage Renal Disease|Portal Hypertension|Kidney Transplantation|Liver Transplantation|Liver Cirrhosis|Kidney|Liver|Splenomegaly|Cholangitis|Splenectomy|Pancytopenia 1120 PKHD1 32128744 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.03.009 0 0 0 188 Humans|Renal Dialysis|Polycystic Kidney, Autosomal Dominant|Autosomal Recessive Polycystic Kidney Disease|Kidney|Kidney Neoplasms|Cysts|Mutation 1120 PKHD1 32118333 Pathol. Int. 2020 10.1111/pin.12917 0 0 0 188 Child|Humans|*Liver Transplantation|*Living Donors|Hepatic Fibrosis, Congenital|*Liver Cirrhosis|Graft Survival|Graft Rejection|Polycystic liver disease|Liver Diseases|Liver|Autosomal Recessive Polycystic Kidney Disease|Risk Factors|Cysts 1120 PKHD1 32068086 Cell. Signal. 2020 PMC7183897 10.1016/j.cellsig.2020.109568 0 0 0 188 Humans|Hepatocyte Nuclear Factor 1-beta|*Disease, Polycystic Kidney|Kidney|NFIB protein, human|*Nuclear Factor I-B|transcription factor nuclear factor 1|Mutations|MicroRNAs|Promoter Regions, Genetic|*Hepatocyte|RNA, Long Noncoding|Genes, Regulator|Cell Line 1120 PLA2G7 32656171 Front Pediatr 2020 PMC7324548 10.3389/fped.2020.00338 0 0 0 376 241 PLA2G7 32636298 Heart 2020 10.1136/heartjnl-2020-316722 0 0 0 376 Humans|*1-Alkyl-2-acetylglycerophosphocholine Esterase|Aortic Valve, Calcification of|*Aortic Valve Stenosis|*Aortic Valve|*Calcinosis|Coronary Artery Disease|Risk Factors 241 PLA2G7 32322464 Acta Pharm Sin B 2020 PMC7161712 10.1016/j.apsb.2019.10.006 1 0 0 376 *Monoacylglycerol Lipases|*Lipid Metabolism|Endocannabinoid|Arachidonic Acids|Glycerides|Amidohydrolases|Enzyme Inhibitors|Arachidonic Acid|Hydrolysis|Prostaglandins|*Metabolic Diseases|Cancer 241 PLA2G7 32310273 J. Infect. Dis. 2020 10.1093/infdis/jiaa196 0 0 0 376 Humans|*Hydroxymethylglutaryl-CoA Reductase Inhibitors|*Proteomics|*HIV Infections|Anticholesteremic Agents|Cholesterol, LDL|TYRP1 protein, human|*Membrane Glycoproteins|Atherosclerosis|*Plasma|Cardiovascular System|Blood Proteins 241 PLA2G7 32252966 Maturitas 2020 10.1016/j.maturitas.2020.02.005 0 0 0 376 Humans|Adult|Female|Male|*B-DNA|Epigenetics|DNA Methylation|Epigenesis, Genetic|ABCG1 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 1|Coronary Heart Disease|Myocardial Infarction|Genetic Predisposition to Disease|Lipids|Phenotype|Lipoprotein|Asian|Hydroxymethylglutaryl-CoA Reductase Inhibitors|PON1 protein, human|Aryldialkylphosphatase|MAP3K13 protein, human|MAP Kinase Kinase Kinases 241 PLA2G7 32152936 J. Mol. Neurosci. 2020 10.1007/s12031-020-01508-9 0 0 0 376 Humans|Male|Female|*Intracranial Arteriovenous Malformations|Intracranial Aneurysms|DNA Methylation|*Asian Continental Ancestry Group|Risk Factors|Area Under Curve|Apo B|Brain|Phospholipases A2 241 PLA2G7 32145524 Pregnancy Hypertens 2020 10.1016/j.preghy.2020.02.005 0 0 0 376 Pregnancy|Female|Humans|*Pre-Eclampsia|PLA2G7 protein, human|*1-Alkyl-2-acetylglycerophosphocholine Esterase|*Chinese|*Genotypes|Polymorphism, Genetic|Polycystic Ovary Syndrome|Alleles|Case-Control Studies 241 PLA2G7 32109154 Genet Test Mol Biomarkers 2020 10.1089/gtmb.2019.0162 0 0 0 376 241 PLAC1 32499871 Oncotarget 2020 PMC7244013 10.18632/oncotarget.27582 0 0 0 109 Humans|Pregnancy|Female|Animals|PLAC1 protein, human|FGF7 protein, human|*Fibroblast Growth Factor 7|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Pregnancy Proteins|*Cell Proliferation|Trophoblast|Placenta|Gene Expression Regulation, Neoplastic|Receptor, Fibroblast Growth Factor, Type 2|MCF-7 Cells|Signal Transduction|Cell Line, Tumor|Carcinoma, Hepatocellular|Phosphorylation|Cell Movement|Liver Neoplasms 91 PLAC1 32286341 Sci Rep 2020 PMC7156695 10.1038/s41598-020-62193-7 0 0 0 109 Humans|Female|Pregnancy|*Trophoblasts|*Pre-Eclampsia|syncytin|Pregnancy Proteins|Placenta|Gene Products, env|Extracellular Vesicles|*Cell-Derived Microparticles|Fetus 91 PLAC1 32231122 Cells 2020 PMC7226750 10.3390/cells9040821 0 0 0 109 Mice|Animals|Male|Female|Humans|*Gene Editing|*CRISPR-Cas Systems|*CRISPR|Fertility|Infertility, Male|Spermatozoa|Mice, Knockout|Testis|Oocyte|Oogenesis|Ovary 91 PLAC1 32153735 Avicenna J Med Biotechnol 2020 PMC7035464 0 0 0 109 Pregnancy|Male|Female|Animals|Cricetinae|Humans|PLAC1 protein, human|Pregnancy Proteins|Immunotherapy|Placenta|*Cricetulus|*CHO Cells|Cancers 91 PLAC1 32090963 Placenta 2020 PMC7167609 10.1016/j.placenta.2020.02.006 0 0 0 109 Mice|Animals|Humans|Female|Pregnancy|IGF1 protein, human|*Insulin-Like Growth Factor I|*Placenta|Syncytiotrophoblast|Fetal Growth Restriction|*Syncytium|Cell Differentiation|*Nanoparticle|PLAC1 protein, human|Pregnancy Proteins 91 PLAC1 31952435 Iran. 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Rheumatol. 2020 10.1007/s10067-020-05212-2 0 0 0 234 Humans|*miRNA|*mRNA|*RNA, Circular|*Lupus Erythematosus, Systemic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Regulatory Networks 325 plag1 32423295 Monoclon Antib Immunodiagn Immunother 2020 10.1089/mab.2020.0010 0 0 0 234 Cricetinae|Sheep|Animals|Endothelial Cells|*Epitopes|Epitope Mapping|*Antibodies, Monoclonal|Antibody Specificity|CHO Cells|Cricetulus|Membrane Glycoproteins|Podocytes|Platelet Aggregation|Flow Cytometry|Point Mutations|Lung|Kidney|*Transcription Factors|Alveolar Epithelial Cells 325 plag1 32365208 J. Anim. Sci. 2020 PMC7247537 10.1093/jas/skaa151 0 0 0 234 Pregnancy|Female|Cattle|Animals|*Breeding|Quantitative Trait Loci|*Phenotype|Genome-Wide Association Study|Single Nucleotide Polymorphism|Genotype|Reproduction 325 plag1 32345665 Cancer Genomics Proteomics 2020 PMC7259886 10.21873/cgp.20184 0 0 0 234 Chondroid Syringoma|Salivary Gland Neoplasms|DNA-Binding Proteins|HMGA2 Protein 325 plag1 32307573 Virchows Arch. 2020 10.1007/s00428-020-02810-y 0 0 0 234 Humans|Male|Middle Aged|Salivary Gland Adenoma, Pleomorphic|*Adenoma, Pleomorphic|Salivary Gland Neoplasm|DNA-Binding Proteins|HMGA2 Protein|CTNNB1 protein, human|*beta Catenin|Salivary Glands|Immunohistochemistry|In Situ Hybridization, Fluorescence|Translocation, Genetic|*Adenoma|Gene Rearrangement|PLAG1 protein, human 325 plag1 32296097 Sci Rep 2020 PMC7160148 10.1038/s41598-020-63516-4 0 0 0 234 Pregnancy|Cattle|Female|Animals|Horses|Genome-Wide Association Study|Sexual Maturation|Breeding|Reproduction|Fertility|Phenotype|Genotype|Body Weight|Models, Genetic|*Phenotypic Plasticity 325 plag1 32240034 Monoclon Antib Immunodiagn Immunother 2020 10.1089/mab.2020.0004 0 0 0 234 Cricetinae|Animals|*Epitope Mapping|Endothelial Cells|*Bear|Epitopes|Antibody Specificity|CHO Cells|anti-endothelial cell antibody|*Autoantibodies|Cricetulus|Antibodies, Monoclonal|Podocytes|Membrane Glycoproteins|*Lymphatic Vessels|Alveolar Epithelial Cells|Platelet Aggregation|Lung|Kidney 325 plag1 32180796 Front Genet 2020 PMC7057717 10.3389/fgene.2020.00123 0 0 0 234 Montana|*Phenotype|*Meat|Breeding|Genome-Wide Association Study|Genotype|Red Meat|Body Composition|Polymorphism, Single Nucleotide 325 plag1 32166108 Arch Anim Breed 2020 PMC7053510 10.5194/aab-63-9-2020 0 0 0 234 Animals|Cattle|*Genetic Markers|Japan|*Phenotype|Breeding|Genotype|Meat|*Fertility|Polymorphism, Single Nucleotide 325 plag1 32007659 J Oral Biosci 2020 10.1016/j.job.2020.01.002 0 0 0 234 Humans|*Acinar Cells|Salivary Gland Neoplasms|*Salivary Glands|*Transcription Factors|Adenoma, Pleomorphic|DNA-Binding Proteins|Gene Expression Regulation, Neoplastic|PLAG1 protein, human 325 plag1 31994243 Genes Chromosomes Cancer 2020 PMC7170037 10.1002/gcc.22835 0 0 0 234 Young Adult|Humans|Child|*Myoepithelioma|*Viscera|EWSR1 protein, human|*RNA-Binding Protein EWS|*Rearrangements, Gene|Calmodulin-Binding Proteins|RNA-Binding Protein FUS|Gene Fusions|Soft Tissue Neoplasms|RNA-Binding Proteins|Oncogene Proteins, Fusion|In Situ Hybridization, Fluorescence|POU5F1 protein, human|Octamer Transcription Factor-3|HMGA2 Protein|*Genes, Regulator|Transcription Factors|Skin Neoplasms 325 plag1 31981700 Genomics 2020 10.1016/j.ygeno.2020.01.012 0 0 0 234 Animals|Cattle|*Perilipin-1|CEBPB protein, human|*CCAAT-Enhancer-Binding Protein-beta|*Adipocytes|Lipolysis|SMAD3 protein, human|*Smad3 Protein|Adipose Tissue|Gene Expression Regulation|Lipid Metabolism|Promoter Regions, Genetic|Activation, Transcriptional|Cell Differentiation 325 plag1 31950472 Head Neck Pathol 2020 PMC7021888 10.1007/s12105-019-01109-y 0 0 0 234 *Myoepithelioma|Pleomorphic Adenoma|Soft Tissue Neoplasms|Calmodulin-Binding Proteins|RNA-Binding Protein EWS|Gene Rearrangement|In Situ Hybridization, Fluorescence|Skin Neoplasms|DNA-Binding Proteins|Gland, Salivary|Immunophenotyping|Biomarkers, Tumor 325 PLCL1 32534097 Neurosci. 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Care Med. 2020 10.1164/rccm.201912-2445OC 0 0 0 350 Humans|Female|*Lymphangioleiomyomatosis|*Transcriptome|*Lung Neoplasms|Tuberous Sclerosis Complex|Tuberous Sclerosis Complex 2 Protein|Lung|Tumor Suppressor Proteins|*Transcriptome Analysis|*Lung Diseases, Interstitial|*B-Lymphocytes 674 pmel 32596061 PeerJ 2020 PMC7306216 10.7717/peerj.9402 0 0 0 350 Animals|Rabbits|Melanocytes|Melanin|*Cell Proliferation|Microphthalmia-Associated Transcription Factor|*Apoptosis|Skin|Cells, Cultured 674 pmel 32580068 Clin Neurol Neurosurg 2020 10.1016/j.clineuro.2020.106028 0 0 0 350 *Medulloblastoma|*Proteomics|Cerebellar Neoplasms|*Gene Expression Profiling|Hedgehog Proteins|Wnt Proteins|beta Catenin|Biomarkers, Tumor 674 pmel 32560567 Genes (Basel) 2020 PMC7349775 10.3390/genes11060660 0 0 0 350 Dogs|Animals|*Mutation|Exon|Phenotype|*Genetic Background|Intron|Alleles|Hair Color|RNA, Messenger 674 pmel 32422549 Eur J Med Chem 2020 10.1016/j.ejmech.2020.112373 0 0 0 350 Humans|Rats|Animals|*Prodrugs|1-methyltryptophan|*Tryptophan|Bioavailability|Intestinal Absorption|*Immunologic Factors|Administration, Oral|Intestines|Cynomolgus Monkeys 674 pmel 32313720 Oncoimmunology 2020 PMC7153840 10.1080/2162402X.2020.1737369 0 0 0 350 Animals|*Melanoma, Experimental|*Transcriptome|*RNA-Seq|*Lymphocytes, Tumor-Infiltrating|CD8-Positive T-Lymphocytes|Programmed Cell Death 1 Receptor|Hepatitis A Virus Cellular Receptor 2|*Whole Exome Sequencing 674 pmel 32299303 Biosci. Biotechnol. Biochem. 2020 10.1080/09168451.2020.1751581 0 0 0 350 Humans|*Melanins|isoimperatorin|*Keratinocytes|Tyrosinase|*Furocoumarins|Whitening Agent, Skin|Cathepsin B|MicroRNAs|CSTB protein, human|Cystatin B 674 pmel 32231230 Sci Rep 2020 PMC7105471 10.1038/s41598-020-62369-1 0 0 0 350 Humans|Neoplasm Recurrence, Local|*Melanoma|*Immunotherapy|Proto-Oncogene Proteins B-raf|Skin Neoplasms|Immunotherapy, Adoptive|T-Lymphocytes|Cell Line, Tumor|*Immunologic Factors 674 pmel 32209638 Cancer Immunol Res 2020 PMC7269835 10.1158/2326-6066.CIR-19-0910 1 0 0 350 *T Cell Receptor|Antigens, Neoplasm|Lymphocyte Activation|Gene Therapy|Cell Line, Tumor|T-Lymphocytes 674 pmel 32159878 Mol. Ecol. 2020 10.1111/mec.15411 0 0 0 350 Animals|*Color|*Salamanders|Pigmentation|Biological Evolution|Lizards|Phenotype|Genetics, Population|Genotype-Phenotype Associations|Genomics|Transcriptome Analysis 674 pmel 32122464 Elife 2020 PMC7075692 10.7554/eLife.52539 0 0 0 350 Animals|Immunotherapy, Adoptive|Lymphocyte Activation|CD8-Positive T-Lymphocytes|gp100 Melanoma Antigen|Melanoma, Experimental|*Phenotype 674 pmel 32078336 Am. J. Respir. Cell Mol. Biol. 2020 10.1165/rcmb.2019-0117OC 0 0 0 350 Humans|Female|*Lymphangioleiomyomatosis|*Immunotherapy, Adoptive|*Adoptive Cell Transfer|gp100 Melanoma Antigen|Lung Neoplasms|Lung|T-Lymphocytes 674 pmel 32041535 BMC Genet. 2020 PMC7011551 10.1186/s12863-020-0824-y 2 0 0 350 Animals|*Inbreeding|*Buffaloes|*Islands|Iran|*Homozygote|*Genome|*Genomics|Genotype|SNPs 674 pmel 32017163 Prostate 2020 10.1002/pros.23957 0 0 0 350 Humans|Male|Mice|Animals|*Disease Models, Animal|gp100 Melanoma Antigen|*Transfections|Dendritic Cells|CD8-Positive T-Lymphocytes|Melanoma, Experimental|Antigens, Neoplasm|Membrane Glycoproteins|Mice, Inbred C57BL|Neoplasm Proteins|Immunotherapy|*Prostate Cancer 674 pomp 32589978 Lancet Haematol 2020 10.1016/S2352-3026(20)30144-7 1 0 0 118 Adult|Humans|*Philadelphia Chromosome|ofatumumab|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Antibodies, Monoclonal|Vincristine|Cyclophosphamide|Doxorubicin|Rituximab|Disease-Free Survival|Antineoplastic Combined Chemotherapy Protocols|Dexamethasone|Burkitt Lymphoma|B-Lymphocytes 588 pomp 32577023 Acta Med. Okayama 2020 10.18926/AMO/59958 0 0 0 118 Humans|*Endoscopic Mucosal Resection|1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine|*Fibrinolytic Agents|*Case-Control Studies|*Prospective Studies|*Drug Users|*Pyrroles|*Sulfonamides|*Stomach Neoplasms|Stomach Ulcer|Proton Pump Inhibitors|Postoperative Hemorrhage|Stomach|Postoperative Complications 588 pomp 32572629 Surg Endosc 2020 10.1007/s00464-020-07753-8 0 0 0 118 *Robotic Surgical Procedures|*Gastrectomy|*Gastroesophageal Reflux|Gastric Bypass|Bariatric Surgery|Obesity, Morbid|Weight Loss|Laparoscopy|Reoperation|Retrospective Studies|Postoperative Complications 588 pomp 32502155 PLoS ONE 2020 PMC7274373 10.1371/journal.pone.0233377 1 0 0 118 Mice|Animals|*Quantitative Trait Loci|*Collaborative Cross Mice|Chromosome Mapping|Alleles|Genotype|Phenotype|Genetic Variation|Polymorphism, Single Nucleotide 588 pomp 32490503 Soft Matter 2020 10.1039/d0sm00492h 0 0 0 118 Animals|*Cell Shape|Fibers, Stress|Actin Cytoskeleton|Cytoskeleton|Actins|Cell Adhesion|Simulations, Computer|Anisotropy|Microtubules|Models, Biological|*Biological Phenomena 588 pomp 32477059 Front Neurosci 2020 PMC7237737 10.3389/fnins.2020.00483 0 0 0 118 Humans|*Dancing|*Sounds|Primary Auditory Cortex|Evoked Potentials, Auditory|Auditory Perception|*Brain|Acoustic Stimulation|Psychomotor Performance|Sensory Feedback|Supplementary Motor Area|Learning 588 pomp 32476110 Gastric Cancer 2020 10.1007/s10120-020-01089-x 0 0 0 118 *Retrospective Studies|*Esophagogastric Junction|*Laparoscopic Surgery|Stomach Neoplasms|Gastroscopy|Gastrointestinal Stromal Tumors|Gastroesophageal Reflux|Treatment Outcome 588 pomp 32425927 Front Immunol 2020 PMC7203212 10.3389/fimmu.2020.00641 0 0 0 118 Humans|Keratosis Linearis with Ichthyosis Congenita and Sclerosing Keratoderma|*Skin Diseases, Genetic|*Skin Abnormalities|Ichthyosis|Keratoderma, Palmoplantar|proteasome maturation protein|Molecular Chaperones|Epidermis|Skin|Syndrome|Proteasome Endopeptidase Complex 588 pomp 32385706 Surg Endosc 2020 10.1007/s00464-020-07601-9 0 0 0 118 *Surgical Mesh|*Abdominal Wall|Hernia, Ventral|Herniorrhaphy|*Abdominoplasty|Postoperative Complications|Hydroxybutyrates|Treatment Outcome|*Prostheses and Implants|Recurrence 588 pomp 32366381 Mol. Cell. Biol. 2020 PMC7324849 10.1128/MCB.00010-20 0 0 0 118 *Proteasome Endopeptidase Complex|CPEB3 protein, human|*RNA-Binding Proteins|NF-E2-Related Factor 1|Basic-Leucine Zipper Transcription Factors|Gene Expression Regulation|*Protein Processing, Post-Translational|*Complement System Proteins 588 pomp 32330411 Neuron 2020 10.1016/j.neuron.2020.03.028 0 0 0 118 Humans|Animals|Mice|*Glycine|Pyrroline Carboxylate Reductases|Phenotype|Microcephaly|Signal Transduction|Glycine Hydroxymethyltransferase|Mitochondria|PYCR2 protein, human 588 pomp 32306943 BMC Public Health 2020 PMC7169026 10.1186/s12889-020-08621-9 0 0 0 118 Humans|Child|Child, Preschool|*Diet, Healthy|*Physical Activity|*Care, Child|Child Day Care Centers|*Child Health|Health Behaviors|Health Promotion|Program Evaluation|Motor Skills|*Movement|*Health Status 588 pomp 32123008 Mol. Cell. Biol. 2020 PMC7189095 10.1128/MCB.00597-19 1 0 0 118 *Ubiquitin|*Retinoblastoma Protein|TP53 protein, human|*Tumor Suppressor Protein p53|*Proteolysis|ATP dependent 26S protease|*Proteasome Endopeptidase Complex|Bortezomib|Cell Line, Tumor|Cytoplasm|Transcription Factor 588 pomp 32084036 Ann. Surg. 2020 10.1097/SLA.0000000000003828 0 0 0 118 *Gastric Bypass|Obesity, Morbid|Gastroplasty|Weight Loss|*Smoking Behavior|Body Mass Index|Risk Factors 588 pomp 32007792 Epidemics 2020 10.1016/j.epidem.2019.100383 0 0 0 118 Bayes Theorem|Computer Simulation|Software|*Infectious Disease|Algorithms|Influenza|Mathematical Models|Models, Biological 588 pomp 31949053 Science 2020 PMC7339343 10.1126/science.aaz5357 2 0 0 118 Animals|*Electron Microscopy|Cryoelectron Microscopy|Microscopy, Fluorescence|*Freezing|Fluorescence|Imaging, Three-Dimensional|*Face|Endoplasmic Reticulum 588 pomp 31899982 Expert Opin Pharmacother 2020 10.1080/14656566.2019.1707805 0 0 0 118 588 POSTN 32647988 World J Surg 2020 10.1007/s00268-020-05586-z 0 0 0 3064 Neoplasm Recurrence, Local|Colorectal Cancer|*Intestines|Biomarkers, Tumor|Neoplastic Stem Cells|Adenocarcinoma|Antigens, CD|Colonic Neoplasms|*Databases, Genetic|Cell Line, Tumor 1117 POSTN 32647861 J. Neuropathol. Exp. Neurol. 2020 10.1093/jnen/nlaa067 0 0 0 3064 Humans|*Pericytes|*Glioma|POSTN protein, human|*Cell Adhesion Molecules|Pilocytic Astrocytoma|Brain Neoplasms|Glioblastoma|*Neovascularization, Pathologic|Oligodendrogliomas|OLIG2 protein, human|Oligodendrocyte Transcription Factor 2|Immunohistochemistry|RNA, Messenger 1117 POSTN 32642695 Neurooncol Adv 2020 PMC7276933 10.1093/noajnl/vdaa040 0 0 0 3064 *Glioblastoma|*Neovascularization, Pathologic|Endothelial Progenitor Cells|Neovascularization, Physiologic|*B Cells|Cells, Cultured 1117 POSTN 32637906 JHEP Rep 2020 PMC7330160 10.1016/j.jhepr.2020.100115 0 0 0 3064 *Extracellular Matrix|*Collagen|Extracellular Matrix Proteins|*Liver|Liver Cirrhosis|Proteomics|Fibrosis|Biomarkers|Disease Progression 1117 POSTN 32627156 Ginekol. Pol. 2020 10.5603/GP.2020.0064 0 0 0 3064 United States|Female|Humans|Pregnancy|*Gynecology|*Obstetrics|POSTN protein, human|*Cell Adhesion Molecules|Glycoprotein|Fibroids|Extracellular Matrix Proteins|Signal Transduction|Ovarian Cancer|Tumor Microenvironment 1117 POSTN 32613365 Ann. Surg. Oncol. 2020 10.1245/s10434-020-08765-3 0 0 0 3064 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Retrospective Studies|Lymphocyte|Esophagectomy|Neutrophils|Prognosis|Carcinoma, Squamous Cell|Platelet|POSTN protein, human|*Cell Adhesion Molecules|Survival Rate|C-Reactive Protein|Inflammation|Follow-Up Studies 1117 POSTN 32611237 Circ. Res. 2020 10.1161/CIRCRESAHA.119.315999 0 0 0 3064 1117 POSTN 32579471 Autophagy 2020 10.1080/15548627.2020.1778292 0 0 0 3064 Pregnancy|Female|Humans|CTNNB1 protein, human|*beta Catenin|*Autophagy|*Uterus|Signal Transduction|Vascular Endothelial Growth Factor A|NOS1 protein, human|Nitric Oxide Synthase Type I|VEGFA protein, human 1117 POSTN 32510239 Cell Transplant 2020 10.1177/0963689720933241 0 0 0 3064 Humans|Adult|*Glioblastoma|*DNA Methylation|*Prognosis|*B-DNA|Brain Neoplasms|Protein Interaction Maps|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Computational Biology|Biomarkers, Tumor|POSTN protein, human|Cell Adhesion Molecules 1117 POSTN 32461137 Mol. Cell. Probes 2020 10.1016/j.mcp.2020.101596 0 0 0 3064 Rats|Animals|*Pyroptosis|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|*Myocardial Reperfusion Injury|Caspase 1|POSTN protein, human|*Cell Adhesion Molecules|Myocytes, Cardiac|Interleukin-1beta|Reactive Oxygen Species|Cell Hypoxia|Hypoxia|Nlrp3 protein, rat 1117 POSTN 32460303 Med. Sci. Monit. 2020 PMC7278529 10.12659/MSM.924934 0 0 0 3064 Humans|*Computational Biology|Gene Ontology|*Allergic Rhinitis|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|*Biomarkers|miRNAs|Databases, Genetic|*Asthma|Rhinitis|Signal Transduction|Genes, Regulator|Nasal Epithelium|POSTN protein, human|Cell Adhesion Molecules 1117 POSTN 32420385 Biomed Res Int 2020 PMC7210524 10.1155/2020/9405909 0 0 0 3064 Humans|Female|Rats|Animals|*Osteogenesis|*Mesenchymal Stem Cells|*Cell Differentiation|Bone Marrow Cells|*Estrogens|POSTN protein, human|*Cell Adhesion Molecules|Osteoporosis|Wnt Signaling Pathway|beta Catenin|Ovariectomy|Oestradiol 1117 POSTN 32416542 Transl Oncol 2020 PMC7248449 10.1016/j.tranon.2020.100789 0 0 0 3064 Humans|Male|POSTN protein, human|*Cell Adhesion Molecules|Prognosis|Circulating Tumor Cells|Prostatic Neoplasms, Castration-Resistant|Receptors, Androgen|Disease-Free Survival|Biomarkers, Tumor|Disease Progression 1117 POSTN 32391563 Biosci. Rep. 2020 PMC7251326 10.1042/BSR20194192 0 0 0 3064 Humans|*Computational Biology|*Urinary Bladder Neoplasms|Phosphatidylinositol 3-Kinases|Gene Ontology|*Disease Progression|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Prognosis|Protein Interaction Maps|Databases, Genetic|Transcriptome|Biomarkers, Tumor|Downregulation|Up-Regulation|Software|Signal Transduction|*Extracellular Matrix 1117 POSTN 32366407 Anticancer Res. 2020 10.21873/anticanres.14233 0 0 0 3064 *Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|POSTN protein, human|*Cell Adhesion Molecules|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Biomarkers, Tumor 1117 POSTN 32354887 In Vivo 2020 PMC7279791 10.21873/invivo.11870 0 0 0 3064 Humans|Dogs|Female|Animals|*Cancer-Associated Fibroblasts|POSTN protein, human|*Cell Adhesion Molecules|Neoplasms, Mammary|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Migration|Cell Line, Tumor|*Cancer, Mammary 1117 POSTN 32344006 Toxicology 2020 10.1016/j.tox.2020.152475 0 0 0 3064 *Hepatic Stellate Cells|*Nuclear Factor-Kappab|curcumol|*Signal Transduction|*Sesquiterpenes|POSTN protein, human|*Cell Adhesion Molecules|Liver Cirrhosis|Carbon Tetrachloride|Cell Movement|Phosphorylation|*Tissue Adhesions 1117 POSTN 32330138 PLoS ONE 2020 PMC7182230 10.1371/journal.pone.0231501 0 0 0 3064 Humans|Mice|Animals|*Discoidin Domain Receptor 1|MMP13 protein, human|Matrix Metalloproteinase 13|Articular Cartilage|Chondrocytes|POSTN protein, human|*Cell Adhesion Molecules|*Cartilage Diseases|Osteoarthritis, Knee|Synovium|Cells, Cultured|Extracellular Matrix Proteins|Signal Transduction|DDR1 protein, human 1117 POSTN 32319226 J. 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Cell Res. 2020 10.1016/j.yexcr.2020.111933 0 0 0 39 Male|*Colorectal Carcinoma|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Cell Movement|*Disease Progression|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Oncogene|Downregulation 20 POTEE 31920968 Front Endocrinol (Lausanne) 2020 PMC6915109 10.3389/fendo.2019.00854 0 0 0 39 20 pou2f3 32617896 J. Mol. Histol. 2020 10.1007/s10735-020-09893-6 0 0 0 144 Mice|Animals|villin|Microfilament Proteins|Microvilli|Cells, Epithelial|Mice, Transgenic|Epithelium|Enterocytes|Intestines|Immunohistochemistry|Mucosa|Gastrointestinal Tract|Pou2f3 protein, mouse|Octamer Transcription Factors 50 pou2f3 32509576 Front Oncol 2020 PMC7251180 10.3389/fonc.2020.00741 0 0 0 144 Humans|Mice|Animals|*Small Cell Lung Carcinoma|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Immunotherapy|Molecular Targeted Therapy|Mutations|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|*Biomarkers|Signal Transduction|Nerve Tissue Proteins|Pou2f3 protein, mouse|Octamer Transcription Factors 50 pou2f3 32473656 Cancer Cell 2020 10.1016/j.ccell.2020.05.001 0 0 0 144 Humans|Mice|Animals|*Small Cell Lung Carcinoma|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Lung Neoplasms|Neuroendocrine Cells|Neuroendocrine Tumors|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Biomarkers, Tumor|Nerve Tissue Proteins|Pou2f3 protein, mouse|Octamer Transcription Factors 50 pou2f3 31988217 eNeuro 2020 PMC7004487 10.1523/ENEURO.0339-19.2020 1 0 0 144 Mice|Animals|*Taste|*Taste Buds|*Signal Transduction|Mice, Knockout|*Neurotransmitter|*Nervous System Physiological Phenomena 50 pou2f3 31953256 Sci Immunol 2020 PMC7176051 10.1126/sciimmunol.aax7224 1 0 0 144 cysteinyl-leukotriene|*Leukotrienes|*Cysteine|Receptors, Leukotriene|Cells, Epithelial|*B Cells|*Respiratory System|Membrane Proteins|Olfactory Mucosa|Gene Expression Regulation|Adenosine Triphosphate 50 pou2f3 31893322 Biochem. Genet. 2020 PMC7113193 10.1007/s10528-019-09945-x 0 0 0 144 Sheep|Animals|*Isoforms|KRT14 protein, human|Keratin-14|Transcription Factor POU|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Differentiation|Cell Proliferation|matrix metalloproteinase 19|Matrix Metalloproteinases, Secreted|Skin 50 POU3F3 32637576 Mol Ther Oncolytics 2020 PMC7321817 10.1016/j.omto.2020.05.014 0 0 0 131 Humans|*Esophageal Squamous Cell Carcinoma|*RNA, Long Noncoding|*Cancer-Associated Fibroblasts|*Cisplatin|Esophageal Neoplasms|*Fibroblast|*Antineoplastic Agents|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Exosomes|Tumor Microenvironment|Cell Line, Tumor|Signal Transduction|*Cell Differentiation|POU3F3 protein, human|POU Domain Factors 67 POU3F3 32615948 BMC Pulm Med 2020 PMC7331167 10.1186/s12890-020-01218-3 0 0 0 131 *Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|*Cell Proliferation|*Downregulation|*Adenocarcinoma|MicroRNAs|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|3' Untranslated Regions|Upregulation 67 POU3F3 32397610 Cancers (Basel) 2020 PMC7281347 10.3390/cancers12051200 0 0 0 131 Humans|*Carcinoma, Renal Cell|*RNA, Long Noncoding|Kidney Neoplasms|*Apoptosis|Biomarkers, Tumor|Cell Proliferation|Kaplan-Meier Estimate|Cell Line, Tumor|Oncogenesis|*Neovascularization, Pathologic|Up-Regulation|Prognosis 67 POU3F3 32236821 Neurotherapeutics 2020 10.1007/s13311-020-00842-5 0 0 0 131 Humans|*Glucosylceramidase|*RNA, Long Noncoding|*Exosomes|*Neural Cell Adhesion Molecule L1|alpha-Synuclein|Parkinson Disease|Lysosomes|*Plasma|*Risk Factors|Autophagy|POU3F3 protein, human|POU Domain Factors 67 POU3F3 32002665 Med Mol Morphol 2020 10.1007/s00795-020-00245-7 0 0 0 131 *Neocortex|Pyriform Cortex|Olfactory Bulb|Olfactory Pathways|Cortex, Olfactory|Smell|Odors|Neurons 67 POU3F4 32048449 Mol Genet Genomic Med 2020 PMC7196461 10.1002/mgg3.1177 1 0 0 75 Humans|Nonsyndromic Deafness|*Deafness|*Asian Continental Ancestry Group|Hearing Loss, Sensorineural|Connexins|Mutations|Pedigree|High-Throughput Nucleotide Sequencing 154 POU3F4 31994726 J. Comp. Neurol. 2020 PMC7316616 10.1002/cne.24867 0 0 0 75 Mice|Animals|*Spiral Ganglion|*Cell Survival|Ear, Inner|POU Domain Factors|Neurons|Progressive hearing loss stapes fixation|Hearing Loss, Sensorineural|Nerve Tissue Proteins|Mice, Knockout|*Cell Death|Transcription Factor|*Mesenchymal Stem Cells|Hearing Loss, Conductive|Genetic Diseases, X-Linked|Mesoderm 154 POU6F1 32045876 Mol Ther Nucleic Acids 2020 PMC7015826 10.1016/j.omtn.2019.12.035 0 0 0 30 *Transcriptome|Nuclear Transfer Techniques|Nuclear Reprogramming|Embryo, Mammalian|Pluripotent Stem Cell|Epigenesis, Genetic|Embryonic Development|DNA Methylation|Histones 34 PRB2 32665711 Nat. Neurosci. 2020 10.1038/s41593-020-0681-z 0 0 0 68 *Autism Spectrum Disorder|*Mutations|*Software 207 PRB2 32650545 Metabolites 2020 10.3390/metabo10070280 0 0 0 68 Humans|*Nymphaea|nymphayol|*Phytosterols|MCF 7 Cells|Proto-Oncogene Proteins c-mdm2|Tumor Suppressor Protein p53|Apoptosis|Reactive Oxygen Species|Cell Proliferation|Cell Cycle Checkpoints 207 PRB2 32636668 Appl Clin Genet 2020 PMC7335280 10.2147/TACG.S245093 0 0 0 68 Male|Humans|Female|Adolescent|Child|Infant, Newborn|Aged|Finland|*Tumors, Germ Cell|Yolk Sac Tumors|Teratomas|Testicular Neoplasms|Embryonal Carcinoma|*Germ Line|Choriocarcinoma|Ovarian Neoplasms 207 PRB2 32482437 Ultrason Sonochem 2020 10.1016/j.ultsonch.2020.105168 0 0 0 68 Acoustic|Microbubbles|Ultrasonography|*Physical Phenomena|*Streams|*Lipids 207 PRB2 32359158 J. Natl. 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Pollut. 2020 PMC7082205 10.1016/j.envpol.2019.113908 1 0 0 177 Arsenites|Keratinocytes|Tumor Suppressor Protein p53|Cell Transformation, Neoplastic|Cell Line 156 PRDM8 32616020 Genome Biol. 2020 PMC7331169 10.1186/s13059-020-02080-6 0 0 0 41 Animals|*Camelids, New World|*Domestication|*Genomics|DNA, Mitochondrial 25 PRDM8 32540493 Genomics 2020 10.1016/j.ygeno.2020.06.010 0 0 0 41 Humans|*Lung|Idiopathic Pulmonary Fibrosis|Chronic Obstructive Pulmonary Disease|*Lung Diseases|*Biomarkers|Asthma|*Chronic Disease|UBQLN4 protein, human|Carrier Proteins|Nuclear Proteins|TOM1L1 protein, human|Adaptor Proteins, Signal Transducing|PAIP2 protein, human|Repressor Proteins|RNA-Binding Proteins 25 PRDM8 32344701 Cancers (Basel) 2020 PMC7226539 10.3390/cancers12041057 0 0 0 41 *Carcinoma, Merkel Cell|*Methyltransferase, Histone|Merkel cell polyomavirus|Polyomavirus Infections|Tumor Virus Infections|Cancer, Skin|Polyoma Virus|*Oncogenesis 25 PRF1 32679391 Environ Int 2020 10.1016/j.envint.2020.105894 0 0 0 3814 Child|Child, Preschool|Male|Pregnancy|Female|Humans|phthalic acid|*Phthalic Acids|*Child Behavior|Environmental Pollutants|Environmental Exposure|Prenatal Exposure Delayed Effects 464 PRF1 32658436 Clin. Lab. 2020 10.7754/Clin.Lab.2019.191136 0 0 0 3814 Infant|Humans|Hemophagocytic lymphohistiocytosis, familial, 2|*Lymphohistiocytosis, Hemophagocytic|*Homozygote|*Mutation|Perforin|Pore Forming Cytotoxic Proteins|*Chinese|PRF1 protein, human 464 PRF1 32638196 J. Clin. Immunol. 2020 10.1007/s10875-020-00814-6 0 0 0 3814 Humans|Child|*Lymphohistiocytosis, Hemophagocytic|Perforin|Membrane Proteins|Mutations|Prognosis|UNC13D protein, human 464 PRF1 32606797 Onco Targets Ther 2020 PMC7319516 10.2147/OTT.S248958 0 0 0 3814 Humans|*Squamous Cell Carcinoma of Head and Neck|*Prognosis|*Receptors, CXCR5|B7-H1 Antigen|Head and Neck Neoplasms|CD8-Positive T-Lymphocytes|CXCR5 protein, human 464 PRF1 32592372 Asian Pac. J. Cancer Prev. 2020 10.31557/APJCP.2020.21.6.1739 0 0 0 3814 Humans|*HCT116 Cells|*Butyrate|*Colorectal Carcinoma|Cancer Stem Cells|Drug Resistance, Neoplasm|*Microarray Analysis|Cell Line, Tumor|Antineoplastic Agents|*Gene Expression|Gene Expression Regulation, Neoplastic|Cell Proliferation|Transcriptome Profiling 464 PRF1 32589707 Blood 2020 10.1182/blood.2019003846 0 0 0 3814 Humans|Mice|Animals|interleukin 18 protein, human|*Interleukin-18|PRF1 protein, human|Perforin|Lymphocytic choriomeningitis virus|Lymphocytic Choriomeningitis|Hemophagocytic Lymphohistiocytosis|Macrophage Activation Syndrome|CD8-Positive T-Lymphocytes|Mice, Knockout|Lymphocyte Activation|Interferon-gamma|Disease Models, Animal|*Virus Inductions 464 PRF1 32542393 Blood Adv 2020 PMC7322966 10.1182/bloodadvances.2020001605 0 0 0 3814 Humans|Lymphohistiocytosis, Hemophagocytic|Signaling Lymphocytic Activation Molecule Associated Protein|DNA Mutational Analysis|Mutation|Sequencing, Next-Generation|Perforin|Qa-SNARE Proteins|Sequence Analysis, DNA|Cohort Studies|North America|SLC7A7 protein, human|Fusion Regulatory Protein 1, Light Chains|UNC13D protein, human|Membrane Proteins 464 PRF1 32502310 Hepatology 2020 10.1002/hep.31412 0 0 0 3814 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Receptors, Antigen, T-Cell, gamma-delta|Cytotoxicity, Immunologic|T-Lymphocytes, Cytotoxic|Perforin|Granzymes|Cell Line, Tumor|Antineoplastic Agents|Receptor, CCR1|Tumor Microenvironment 464 PRF1 32474905 Clin. Exp. Immunol. 2020 10.1111/cei.13470 0 0 0 3814 Humans|*Carcinoma, Hepatocellular|*Hepatitis B virus|Hepatitis B, Chronic|*Liver Neoplasms|*CD8-Positive T-Lymphocytes|*Hepatitis B|GZMA protein, human|Granzyme B|*Tumor Necrosis Factor-alpha|GZMB protein, human|Hepatitis A Virus Cellular Receptor 2|CD4-Positive T-Lymphocytes|PRF1 protein, human|Perforin 1|CTLA4 protein, human|Cytotoxic T-Lymphocyte Antigen 4|Interferon-gamma|Tumor Microenvironment 464 PRF1 32441058 Australas. J. Dermatol. 2020 10.1111/ajd.13325 1 0 0 3814 Humans|*Transcriptome|*Epigenome|Monozygotic Twins|CpG Islands|DNA Methylation|Epigenesis, Genetic|Gene Expression Regulation|Psoriasis 464 PRF1 32414906 Cancer Discov 2020 10.1158/2159-8290.CD-RW2020-072 0 0 0 3814 Granzymes|Perforin|CD8-Positive T-Lymphocytes|T-Lymphocytes, Cytotoxic|Pore Forming Cytotoxic Proteins 464 PRF1 32413598 Cell. Immunol. 2020 10.1016/j.cellimm.2020.104118 0 0 0 3814 *Transcription Factors|*Lymphocyte Activation|T-Cell Subsets|*Cell Differentiation|Immunologic Memory|CD4-Positive T-Lymphocytes|Adoptive Transfer|Interferon-gamma|*Hematopoiesis 464 PRF1 32375849 Orphanet J Rare Dis 2020 PMC7201972 10.1186/s13023-020-01390-z 0 0 0 3814 *Lymphohistiocytosis, Hemophagocytic|Perforin|Signaling Lymphocytic Activation Molecule Associated Protein|Mutations|Genetic Testing|Membrane Proteins|*Genotype|China 464 PRF1 32366382 Mol. Cell. Biol. 2020 10.1128/MCB.00150-20 0 0 0 3814 *Phosphorylation|Yeast, Fission|CDK9 protein, human|Cyclin-Dependent Kinase 9|RNA Polymerase II|Transcriptional Elongation Factors|Schizosaccharomyces pombe Proteins|Positive Transcription Elongation Factor B|Transcription, Genetic|Chromosomal Proteins, Non-Histone|Chromatin|Binding Sites|Amino Acid Sequence|Spt5 protein, S pombe 464 PRF1 32264809 Comb. Chem. 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Neurosci. 2020 10.31083/j.jin.2020.01.1250 0 0 0 3814 Humans|Male|Adolescent|Hemophagocytic lymphohistiocytosis, familial, 2|*Lymphohistiocytosis, Hemophagocytic|Perforin|Magnetic Resonance Imaging|Brain|Cerebellum|Mutation 464 PRF1 32245292 Iran J Allergy Asthma Immunol 2020 10.18502/ijaai.v18i5.1911 0 0 0 3814 Male|Humans|Female|*Lymphohistiocytosis, Hemophagocytic|Iran|*Genetic Testing|Mutations|DNA Mutational Analysis|Intron|Exon|Perforin|Pore Forming Cytotoxic Proteins|Qa-SNARE Proteins|Missense Mutation|*Immunologic Deficiency Syndromes|Base Sequence|UNC13D protein, human|Membrane Proteins 464 PRF1 32198610 World J Pediatr 2020 10.1007/s12519-020-00351-7 1 0 0 3814 *Perforin|*Lymphohistiocytosis, Hemophagocytic|*Polymorphism, Genetic|Mutation 464 PRF1 32194620 Front Genet 2020 PMC7064636 10.3389/fgene.2020.00126 0 0 0 3814 Child|Humans|Hemophagocytic lymphohistiocytosis, familial, 2|*Lymphohistiocytosis, Hemophagocytic|Retrospective Studies|Perforin|Mutation|Mutation, Missense|Killer Cells, Natural|Asian Continental Ancestry Group 464 PRF1 32148351 Indian J Crit Care Med 2020 PMC7050167 10.5005/jp-journals-10071-23329 0 0 0 3814 Humans|Infant|Child|Adolescent|*Lymphohistiocytosis, Hemophagocytic|Heterozygote|*Tuberculosis|Mutation|Diagnosis, Differential|Antitubercular Agents 464 PRICKLE2 32641624 Cell Struct. Funct. 2020 10.1247/csf.20028 0 0 0 83 *Axon Initial Segment|Autism Spectrum Disorder|Proteomics|Axons|Neurons|Hippocampus|Ankyrins|Cells, Cultured|Epilepsy 50 PRIMA1 32181765 Magy Onkol 2020 0 0 0 187 *cfDNA|*DNA Methylation|*Colorectal Cancer|Adenoma|Promoter Regions, Genetic|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Biomarkers, Tumor|DNA, Neoplasm|Membrane Proteins|Immunohistochemistry|Epigenesis, Genetic|*Mutation|Gene Expression Regulation, Neoplastic|Cancer Screening|Epigenetic|*Colonic Neoplasms 67 PRM1 32574793 J. Biotechnol. 2020 10.1016/j.jbiotec.2020.06.012 0 0 0 6 *Malonyl CoA|Bacillus subtilis|Metabolic Engineering|Transcription Factors|Bacterial Proteins|Promoter Regions, Genetic|Polyketides|Biosensing Techniques|Acids, Fatty 379 PRM1 32308937 Gastroenterol Hepatol Bed Bench 2020 PMC7149810 0 0 0 6 Humans|*Celiac Disease|*T-Lymphocytes|Diet, Gluten Free|Glutens|Intestinal Mucosa|Patient Compliance 379 PRM1 32300591 Front Cell Dev Biol 2020 PMC7142241 10.3389/fcell.2020.00212 0 0 0 6 Animals|Male|*Spermatogenesis|Spermatogonia|Testis|Spermatozoa|Spermatocytes|*Animals, Genetically Modified|Fertility 379 PRM1 32227991 ACS Synth Biol 2020 10.1021/acssynbio.9b00378 0 0 0 6 *Malonyl CoA|Bacillus subtilis|Transcription Factors|Metabolic Engineering|Promoter Regions, Genetic|Bacterial Proteins|Saccharomyces cerevisiae|Transcription, Genetic|Biosensors|Fatty Acids|PRM1 protein, S cerevisiae|Membrane Proteins|Saccharomyces cerevisiae Proteins 379 PRM1 32146776 Clin Exp Reprod Med 2020 PMC7127905 10.5653/cerm.2019.03188 0 0 0 6 Humans|Male|Female|Pregnancy|*Protamines|*Transcriptome|*Vitamin C|*Sperm|Infertility, Male|Sperm Motility|*Abortion, Habitual|Chromatin|Histones|*Vitamins|RNA, Messenger|*Microarray Analysis 379 PRM1 31932482 Mol. Cell. Biol. 2020 PMC7076252 10.1128/MCB.00228-19 0 0 0 6 Male|Female|Mice|Animals|*Transcription Factor|*Spermiogenesis|Transcription Factor TFIID|TATA-Binding Protein Associated Factors|Testis|Ovary|*Gene Expression Regulation 379 PRM2 32533872 Reprod. Domest. Anim. 2020 10.1111/rda.13744 0 0 0 108 Cattle|Animals|Male|Humans|Sperm Motility|*Freezing|crocin|*Sperm|Semen Preservation|Cryoprotective Agents|*Carotenoids|Acrosome|Cryopreservation|*Protamines|Semen|Semen Analysis|Glycerol|*Apoptosis|Flow Cytometry|*Membrane Lipids|Cell Survival|Plasma Membrane 158 PRM2 32504620 Cryobiology 2020 10.1016/j.cryobiol.2020.05.015 0 0 0 108 Male|Humans|Dogs|Animals|*Kinetin|*Sperm|Semen Preservation|Cryopreservation|Cryoprotective Agents|Semen Analysis|Sperm Motility|Semen|Acrosomes|protamine 2|Protamines|Reactive Oxygen Species|Plasma Membrane|Chromatin|Dietary Supplements|ROMO1 protein, human|Membrane Proteins|Mitochondrial Proteins 158 PRM2 32308937 Gastroenterol Hepatol Bed Bench 2020 PMC7149810 0 0 0 108 Humans|*Celiac Disease|*T-Lymphocytes|Diet, Gluten Free|Glutens|Intestinal Mucosa|Patient Compliance 158 PRM2 32146776 Clin Exp Reprod Med 2020 PMC7127905 10.5653/cerm.2019.03188 0 0 0 108 Humans|Male|Female|Pregnancy|*Protamines|*Transcriptome|*Vitamin C|*Sperm|Infertility, Male|Sperm Motility|*Abortion, Habitual|Chromatin|Histones|*Vitamins|RNA, Messenger|*Microarray Analysis 158 PRM2 31932482 Mol. Cell. Biol. 2020 PMC7076252 10.1128/MCB.00228-19 0 0 0 108 Male|Female|Mice|Animals|*Transcription Factor|*Spermiogenesis|Transcription Factor TFIID|TATA-Binding Protein Associated Factors|Testis|Ovary|*Gene Expression Regulation 158 PROM1 32646556 Ophthalmol Retina 2020 10.1016/j.oret.2020.02.009 0 0 0 583 Humans|*Cone-Rod Dystrophies|*Fundus Oculi|*Retinitis Pigmentosa|Lipofuscin|Fluorescein Angiography|*Retinal Cone Photoreceptor Cells|Retinal Pigment Epithelium|Ophthalmoscopy|Macular Degeneration|Tomography, Optical Coherence|Optical Imaging 2531 PROM1 32622311 Transl Oncol 2020 PMC7332530 10.1016/j.tranon.2020.100819 0 0 0 583 *Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Mutations|Heterozygote|*Upregulation|DNA Methylation|*Transcriptional Activation|*Neural Stem Cell|*Biomarkers 2531 PROM1 32554499 Proc. Natl. Acad. Sci. U.S.A. 2020 10.1073/pnas.1920829117 0 0 0 583 Nerve Regeneration|Axons|Ganglia, Spinal|Sciatic Nerve|Neurons|Peripheral Nerve Injury|*Stem Cell|Cells, Cultured 2531 PROM1 32534057 Gene 2020 10.1016/j.gene.2020.144890 0 0 0 583 Humans|Child|*Stargardt Disease|*Chinese|Macular Degeneration|Pedigree|Exons|Heterozygote|Retinal Dystrophies|Mutation|Genetic Association Studies|ATP-Binding Cassette Transporters|Genetic Variation|BEST1 protein, human|Bestrophins 2531 PROM1 32460847 Stem Cell Res Ther 2020 PMC7251672 10.1186/s13287-020-01729-0 0 0 0 583 Humans|*Human Embryonic Stem Cells|Pluripotent Stem Cells|*Teratoma|Embryonic Stem Cells|Cell Differentiation|Cell Line|Preimplantation Embryos|Prominin 1|Cancer Stem Cell|Cell Proliferation 2531 PROM1 32423767 Ophthalmology 2020 10.1016/j.ophtha.2020.04.008 0 0 0 583 *Retina|*Retinal Disease|Retinitis Pigmentosa|DNA Mutational Analysis|Peripherins|Eye Proteins|Pedigree|Genetic Testing|*Cohort Studies|Mutation|United Kingdom 2531 PROM1 32401642 Autophagy 2020 10.1080/15548627.2020.1752548 0 0 0 583 Female|Pregnancy|Humans|*Autophagy|Apoptosis Regulatory Proteins|Endoplasmic Reticulum Stress|Signal Transduction|Apoptosis|*Cancer|*Endometrium 2531 PROM1 32347296 Biosci. Rep. 2020 10.1042/BSR20200514 0 0 0 583 Humans|Child|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Myeloid-Lymphoid Leukemia Protein|Histone-Lysine N-Methyltransferase|Gene Rearrangement|Hematopoietic Stem Cell Transplantation|Gene Expression Profiling|Module, Gene|Gene Expression|HOXA10 protein, human|Homeobox A10 Proteins|FUT4 protein, human|Fucosyltransferases 2531 PROM1 32242051 Leukemia 2020 10.1038/s41375-020-0808-y 0 0 0 583 Humans|Infant|Child|Myeloid-Lymphoid Leukemia Protein|*Promoter Regions, Genetic|Oncogene Proteins, Fusion|Histone-Lysine N-Methyltransferase|Gene Expression Regulation, Leukemic|*Cancer Stem Cell|Leukemia|Enhancer Elements, Genetic|Methylation|Histones|Prominin 1|Cell Line, Tumor|MLL-AF4 fusion protein, human|PROM1 protein, human 2531 PROM1 32222998 Hepatology 2020 10.1002/hep.31252 0 0 0 583 Humans|*Organoids|*Biliary Tree|Bile Ducts, Extrahepatic|Intrahepatic Bile Ducts|Liver|Epithelial Cells 2531 PROM1 32219447 Blood 2020 10.1182/blood.2019003701 0 0 0 583 Humans|*Leukemia, Myeloid, Acute|Proto-Oncogenes|MDS1 and EVI1 Complex Locus Protein|Translocation, Genetic|Transcription Factors|GATA2 protein, human|GATA2 Transcription Factor|Karyotyping|Chromosome Aberrations|In Situ Hybridization, Fluorescence|Genes, Regulator|MECOM protein, human 2531 PROM1 32201384 J. 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Chem. 2020 PMC7196652 10.1074/jbc.RA119.011253 0 0 0 583 Animals|Humans|*Zebrafish|*AC133 Antigen|Zebrafish Proteins|Cilia|Body Patterning|Photoreceptor Cells|Mutation 2531 PROM1 32197467 Cells 2020 PMC7140693 10.3390/cells9030746 0 0 0 583 Humans|*Carcinoma, Hepatocellular|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Liver Neoplasms|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|Cell Movement|Cell Line, Tumor|Viability, Cell|Apoptosis|Hep G2 Cells|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Proliferation|BX795|Pyrimidines|Thiophenes 2531 PROM1 32176088 Medicine (Baltimore) 2020 10.1097/MD.0000000000019491 0 0 0 583 Humans|*Squamous Cell Carcinoma of Head and Neck|*DNA Methylation|Head and Neck Neoplasms|*Promoter Regions, Genetic|Prognosis|Carcinoma, Squamous Cell|Proportional Hazards Models|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease-Free Survival|Bioinformatic|Tumor Stem Cells|*Genes, Regulator|PROM1 protein, human|AC133 Antigen 2531 PROM1 32165211 Life Sci. 2020 10.1016/j.lfs.2020.117536 0 0 0 583 Humans|*Glioblastoma|*Progesterone|Brain Tumors|Neoplastic Stem Cells|AC133 Antigen|*Number, Cell|Glioma|Spheroids, Cellular|Cell Differentiation|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Antigens, CD 2531 PROM1 32153627 Front Genet 2020 PMC7046682 10.3389/fgene.2019.01378 1 0 0 583 *Glioblastoma|*Consensus|*Survival Analysis|Prognosis|Transcriptome Profiles|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Biomarkers, Tumor|Proportional Hazards Models 2531 PROM1 32118031 Front Mol Biosci 2020 PMC7010860 10.3389/fmolb.2020.00003 0 0 0 583 Humans|*Squamous Cell Carcinoma of Head and Neck|*Lymphatic Metastasis|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Lymph Nodes|Cancer Stem Cells|Biomarkers, Tumor 2531 PROM1 32058643 Cancer Sci. 2020 PMC7226280 10.1111/cas.14345 1 0 0 583 Humans|bufalin|*Factor B|*Multidrug Resistance|*Bufanolides|*Colorectal Cancer|Drug Resistance, Neoplasm|Antineoplastic Agents|AC133 Antigen|Signal Transduction|Neoplastic Stem Cells|Cell Line, Tumor|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|ATP Binding Cassette Transporter, Subfamily B|Cell Proliferation|*Colonic Neoplasms 2531 PROM1 32036094 J Mol Diagn 2020 10.1016/j.jmoldx.2020.01.003 0 0 0 583 Humans|Female|DNA Copy Number Variations|Comparative Genomic Hybridization|Retinitis Pigmentosa|DNA Mutational Analysis|Retinal Dystrophies|Sequencing, Next-Generation|Pedigree|Mutations|Genotype-Phenotype Associations|Eye Proteins|Phenotype|Genetic Counseling|Cohort Studies 2531 PROM1 31897247 J Cancer 2020 PMC6930440 10.7150/jca.29038 0 0 0 583 2531 PRPH2 32660024 Genes (Basel) 2020 10.3390/genes11070773 0 0 0 410 Peripherins|DNA Mutational Analysis|Electroretinography|Phenotype|Pedigree|Fluorescein Angiography|Mutations|Macular Degeneration 214 PRPH2 32646556 Ophthalmol Retina 2020 10.1016/j.oret.2020.02.009 0 0 0 410 Humans|*Cone-Rod Dystrophies|*Fundus Oculi|*Retinitis Pigmentosa|Lipofuscin|Fluorescein Angiography|*Retinal Cone Photoreceptor Cells|Retinal Pigment Epithelium|Ophthalmoscopy|Macular Degeneration|Tomography, Optical Coherence|Optical Imaging 214 PRPH2 32579694 Ophthalmic Surg Lasers Imaging Retina 2020 10.3928/23258160-20200603-06 0 0 0 410 Humans|*Follow-Up Studies|Choroidal Neovascularization|Ranibizumab|Bevacizumab|Fluorescein Angiography|Intravitreal Injections|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Visual Acuity|Tomography, Optical Coherence|Retinal Dystrophies|Fundus Oculi|Vascular Endothelial Growth Factors|Mutation 214 PRPH2 32534057 Gene 2020 10.1016/j.gene.2020.144890 0 0 0 410 Humans|Child|*Stargardt Disease|*Chinese|Macular Degeneration|Pedigree|Exons|Heterozygote|Retinal Dystrophies|Mutation|Genetic Association Studies|ATP-Binding Cassette Transporters|Genetic Variation|BEST1 protein, human|Bestrophins 214 PRPH2 32531846 Hum. Mutat. 2020 10.1002/humu.24065 0 0 0 410 Humans|*Genotype-Phenotype Associations|Peripherins|Retinal Dystrophies|Phenotype|Pedigree|Genotype|Mutation|*Cohort Studies 214 PRPH2 32516403 Invest. Ophthalmol. Vis. Sci. 2020 10.1167/iovs.61.6.17 0 0 0 410 *Cone-Rod Dystrophies|riboflavin-binding protein|*Retina|*Membrane Transport Proteins|Retinal Degeneration|Retinal Cone Photoreceptor Cells|Peripherins|Eye Proteins|Retinal Pigment Epithelium|TSPAN32 protein, human|Tetraspanins|4,6-dinitro-o-cresol|Dinitrocresols|Riboflavin 214 PRPH2 32423767 Ophthalmology 2020 10.1016/j.ophtha.2020.04.008 0 0 0 410 *Retina|*Retinal Disease|Retinitis Pigmentosa|DNA Mutational Analysis|Peripherins|Eye Proteins|Pedigree|Genetic Testing|*Cohort Studies|Mutation|United Kingdom 214 PRPH2 32410962 Front Cell Neurosci 2020 PMC7198881 10.3389/fncel.2020.00092 0 0 0 410 *Peripherins|Retinal Rod Photoreceptor Cells|Retinitis Pigmentosa|Retinal Cone Photoreceptor Cells|Retinal Degeneration|Eye Proteins|Mutations|Membrane Proteins 214 PRPH2 32345050 Eur J Ophthalmol 2020 10.1177/1120672120919064 0 0 0 410 *Retinaldehyde|*Homozygote|Fundus Albipunctatus|Retinal Diseases|Retinitis Pigmentosa|*Frameshift Mutation|Electroretinography|Night Blindness|Fluorescein Angiography|Fundus Oculi|Mutation|Tomography, Optical Coherence|Visual Fields|Visual Acuity 214 PRPH2 32313077 Sci Rep 2020 PMC7171121 10.1038/s41598-020-63519-1 0 0 0 410 Humans|Mice|Animals|*Ciliary Neurotrophic Factor|*Retinal Degeneration|*Transcriptome|*Retina|Photoreceptors, Cone|Retinitis Pigmentosa|Photoreceptor Cells, Vertebrate|*Disease Models, Animal|Electroretinography|Transgenic Mouse|Rhodopsin|Glia 214 PRPH2 32213850 Cells 2020 PMC7140794 10.3390/cells9030784 0 0 0 410 *Peripherins|*Retina|Photoreceptors, Cone|Retinal Rod Photoreceptor Cells|TSPAN32 protein, human|Tetraspanins|Retinal Degeneration|Eye Proteins|Macular Degeneration|Membrane Proteins|Mutations 214 PRPH2 32010191 Front Genet 2020 PMC6977438 10.3389/fgene.2019.01334 0 0 0 410 Animals|*Loaches|Genome, Mitochondrial|*Transcriptome Profiling|Phylogeny|Caves|Sequence Analysis, DNA|Eyes 214 PRPH2 31914632 FASEB J. 2020 10.1096/fj.201901888R 2 0 0 410 Humans|Mice|Animals|Peripherins|Retinal Cone Photoreceptor Cells|Retinitis Pigmentosa|Retinal Rod Photoreceptor Cells|Retinal Degeneration|Eye Proteins|Rod Outer Segment|Macular Degeneration|Mutation|Heterozygotes|Gene Knock-In Techniques|Membrane Proteins 214 Prrx1 32643087 Clin Oral Investig 2020 10.1007/s00784-020-03443-w 0 0 0 589 Humans|Mice|Animals|Otocephaly|*Craniofacial Abnormalities|*Jaw Abnormalities|Microstomia|Holoprosencephaly|Branchial Region|PRRX1 protein, human|Ear|Otx Transcription Factors|Abnormalities, Multiple|Heterozygote|Phenotype|*Facial Bones|Face|Tongue|Mandible|Mutations 288 Prrx1 32639113 Birth Defects Res 2020 10.1002/bdr2.1758 0 0 0 589 Pregnancy|Female|Humans|Otocephaly|Democratic Republic of the Congo|*Craniofacial Abnormalities|*Jaw Abnormalities|Holoprosencephaly|Abnormalities, Multiple|Otx Transcription Factors|PRRX1 protein, human|Ultrasonography, Prenatal|*Facial Bones|Mutations|Zambia 288 Prrx1 32635929 J. 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IGF Res. 2020 10.1016/j.ghir.2020.02.003 0 0 0 589 Animals|*Nicotine|*Epigenesis, Genetic|*Gland, Pituitary|PRRX1 protein, human|*Homeodomain Proteins|*Pituitary Diseases|*Stem Cells|*Cell Proliferation|Pituitary Gland, Anterior|Anterior Pituitary Hormones|Cell Differentiation|Growth Hormone|Endocrine Cells|*Cell Cycle 288 Prrx1 32100971 Mol Genet Genomic Med 2020 PMC7196462 10.1002/mgg3.1178 1 0 0 589 Humans|Otocephaly|*Craniofacial Abnormalities|*Jaw Abnormalities|Branchial Region|Microstomia|*Phenotypes|Abnormalities, Multiple|PRRX1 protein, human|Homeodomain Proteins|SMAD3 protein, human|*Smad3 Protein|Tongue|*Facial Bones 288 Prrx1 32022343 Dev. Dyn. 2020 10.1002/dvdy.158 1 0 0 589 *Patellar Ligament|*Patella|*Knee Joint|Anterior Cruciate Ligament|Anterior Cruciate Ligament Injuries|Tendons|Rupture|Tibia|Femur 288 Prrx1 31981416 FEBS Lett. 2020 10.1002/1873-3468.13739 0 0 0 589 *Mesenchymal Stem Cells|*Chondrogenesis|*Osteogenesis|*Cell Differentiation|Osteoblasts|RELA protein, human|*Transcription Factor RelA|Chondrocytes|PRRX1 protein, human|Homeodomain Proteins|Cells, Cultured|Cell Proliferation 288 Prrx1 31969185 Acta Vet. Scand. 2020 PMC6977343 10.1186/s13028-020-0503-z 0 0 0 589 Sheep|Animals|Otocephaly|*Craniofacial Abnormalities|*Genes, Homeobox|Branchial Region|Microstomia|*Sheep, Domestic|PRRX1 protein, human|Abnormalities, Multiple|Otx Transcription Factors|Syndromes|*Food Hypersensitivity 288 Prrx1 31931171 Heart Rhythm 2020 10.1016/j.hrthm.2020.01.006 0 0 0 589 *Risk Factors|*Atrial Fibrillation|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Risk Assessment|ROC Curve 288 Prrx1 31913156 Am. J. Surg. 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Genet. 2020 10.1111/cge.13722 0 0 0 17 Humans|*Microphthalmos|Australia|Hyperopia, High|Hyperopia|Mutations|Pedigree|Eye Diseases, Hereditary|Eyes|Refractive Error|Membrane Proteins|Serine Proteases|*Cohort Studies|Glaucoma, Angle-Closure|Phenotypes|Haplotypes 26 PRSS56 31992737 Sci Rep 2020 PMC6987234 10.1038/s41598-019-57338-2 1 0 0 17 Humans|Nanophthalmos 2|*Microphthalmos|Retinitis Pigmentosa|Pseudopapilledema|Eye Diseases, Hereditary|Mutations|Pedigree|Hyperopia|Homozygote|Exon|Base Sequence|Membrane Proteins|Serine Proteases|Genotype-Phenotype Correlations|Optic Nerve Diseases|Cohort Studies|PRSS56 protein, human 26 prune2 32378780 Cancer Sci. 2020 10.1111/cas.14446 0 0 0 110 Humans|*Cardiotoxicity|*Genome-Wide Association Study|*Anthracyclines|Trastuzumab|*Antibiotics, Antineoplastic|Receptor, ErbB-2|Doxorubicin|Antineoplastic Combined Chemotherapy Protocols|Antibodies, Monoclonal, Humanized|Single Nucleotide Polymorphisms|Republic of Korea 34 PSRC1 32620998 J. Mol. Med. 2020 10.1007/s00109-020-01942-7 0 0 0 141 *Progranulins|Diabetes Mellitus, Type 2|Phylogeny|Promoter Regions, Genetic|YY1 Transcription Factor|Protein Binding|Polymorphism, Genetic 90 PSRC1 32373157 Front Genet 2020 PMC7186505 10.3389/fgene.2020.00320 0 0 0 141 *Coronary Artery Disease|Genome-Wide Association Study|Linkage Disequilibrium|Gene Regulatory Networks|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Quantitative Trait Loci|Signal Transduction 90 PSRC1 32238911 Eur. J. Hum. Genet. 2020 10.1038/s41431-020-0619-7 0 0 0 141 Humans|*Whole Exome Sequencing|*Attention Deficit Disorder with Hyperactivity|*Multifactorial Inheritance|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pedigree|High-Throughput Nucleotide Sequencing|Mutation|Alleles|PTP4A3 protein, human|Neoplasm Proteins|Protein Tyrosine Phosphatases 90 PSRC1 31969989 NPJ Genom Med 2020 PMC6965183 10.1038/s41525-019-0109-4 1 0 0 141 Humans|Adult|*Genome-Wide Association Study|*Pharmacogenetics|Low Density Lipoprotein Cholesterol|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Polymorphism, Single Nucleotide|Phenotypes|Cohort Studies 90 PTAFR 32329883 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202004_20869 0 0 0 671 Mice|Animals|MicroRNAs|*Myocardial Infarction|Fibrosis|Fibroblasts|Apoptosis 39 PTAFR 32168105 Med Sci Sports Exerc 2020 10.1249/MSS.0000000000002291 0 0 0 671 Animals|Mice|Bioinformatics|Gene Ontology|Gene Expression Profiling|Protein Interaction Maps|Gene Regulatory Networks|*Signal Transduction|Gene Expression Regulation, Neoplastic|Databases, Genetic|Protein Interaction Mapping|Transcriptome|Software|Biomarkers, Tumor|*Biological Phenomena|*Biochemical Phenomena|Melanoma 39 PTBP2 32081131 Elife 2020 PMC7058386 10.7554/eLife.53557 1 0 0 322 Polypyrimidine Tract-Binding Protein|Heterogeneous-Nuclear Ribonucleoproteins|Alternative Splicing|TYRP1 protein, human|*Membrane Glycoproteins|RNA Binding Protein|Exons|RNA, Messenger|Nerve Tissue Proteins|*Lymphocyte Activation|*Hematopoiesis|B-Lymphocytes 77 PTP4A3 32652076 Dev. Cell 2020 10.1016/j.devcel.2020.06.013 0 0 0 1135 Humans|Animals|*Melanocyte|*Cell Differentiation|Zebrafish|Zebrafish Proteins|Microphthalmia-Associated Transcription Factor|Melanoma|*Pigmentation|Gene Expression Regulation, Developmental|Mutation|Stem Cells|DDX21 protein, human|DEAD-box RNA Helicases 266 PTP4A3 32616539 J. Clin. Pathol. 2020 10.1136/jclinpath-2020-206728 0 0 0 1135 *Pituitary Neoplasms|Adenoma|Immunohistochemistry|Protein Tyrosine Phosphatases|Neoplasm Proteins 266 PTP4A3 32413665 Sci. 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Genet. 2020 10.1038/s41431-020-0619-7 0 0 0 1135 Humans|*Whole Exome Sequencing|*Attention Deficit Disorder with Hyperactivity|*Multifactorial Inheritance|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pedigree|High-Throughput Nucleotide Sequencing|Mutation|Alleles|PTP4A3 protein, human|Neoplasm Proteins|Protein Tyrosine Phosphatases 266 PTP4A3 32044604 Ecotoxicol. Environ. Saf. 2020 10.1016/j.ecoenv.2020.110267 0 0 0 1135 Humans|*Endosulfan|Phosphatidylinositol 3-Kinases|*Human Umbilical Vein Endothelial Cells|*Signal Transduction|*Cell Migration|PTK2 protein, human|Focal Adhesion Kinase 1|Phosphoinositide 3 Kinase|Proto-Oncogene Proteins c-akt|Nuclear Factor-Kappab|Focal Adhesion Kinase|Phosphorylation|Neovascularization, Pathologic|Oxidative Stress|Cells, Cultured|*Protein Tyrosine Phosphatases, Non-Receptor|PTP4A3 protein, human|Neoplasm Proteins 266 PTP4A3 32024182 Int J Environ Res Public Health 2020 PMC7037067 10.3390/ijerph17030910 0 0 0 1135 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Benzene|*Cell Proliferation|*Apoptosis|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|Signal Transduction|Cell Line, Tumor|quinone|Benzoquinones|Vascular Endothelial Growth Factor A|Downregulation|PTP4A3 protein, human|Neoplasm Proteins|Protein Tyrosine Phosphatases 266 PTP4A3 32001668 Oncogenesis 2020 PMC6992623 10.1038/s41389-020-0192-5 1 0 0 1135 Humans|Mice|Animals|PTP4A3 protein, human|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Protein Tyrosine Phosphatases|Neoplasm Proteins|Cell Migration|Cell Line, Tumor|Signal Transduction|*Disease Progression|*Protein Tyrosine Phosphatases, Non-Receptor|T-Lymphocytes|Ptp4a3 protein, mouse|Immediate-Early Proteins 266 PTPRCAP 31991061 Cancer Med 2020 PMC7064027 10.1002/cam4.2849 2 0 0 34 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|DNA Repair|*Gene Expression|Mutation|Genomic Instability|DNA Damage|Biomarkers, Tumor 48 PTPRE 31889940 Clin Proteomics 2020 PMC6927194 10.1186/s12014-019-9262-0 0 0 0 152 Humans|Female|*Carcinoma, Ovarian Epithelial|*Peptides|Spectrometry, Mass, Electrospray Ionization|Chromatography, Liquid|Tandem Mass Spectrometry|Proteomics|*Ovarian Cancer|Proteins|*Plasma 70 PTPRM 32663515 Biochim Biophys Acta Gen Subj 2020 10.1016/j.bbagen.2020.129682 0 0 0 98 Humans|Pilot Projects|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|Prognosis|Biomarkers, Tumor|Adenocarcinoma|PTPRB protein, human|*Receptor-Like Protein Tyrosine Phosphatases, Class 3|Survival Rate|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|*Disease Progression|PTPRM protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 2|PSMD11 protein, human|Proteasome Endopeptidase Complex 52 PTPRM 32056145 J. Neurooncol. 2020 PMC7136185 10.1007/s11060-020-03424-9 0 0 0 98 Child|Humans|*Medulloblastoma|*Genome-Wide Association Study|Cerebellar Neoplasms|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Germ-Line Mutation|Sweden 52 PTPRM 32023328 PLoS ONE 2020 PMC7001972 10.1371/journal.pone.0228778 0 0 0 98 Humans|Russia|*Natural Selection|*Genomics|Allele Frequency|Genetics, Population|Genome, Human|Haplotype|Genetic Variation|Biological Evolution|Evolution, Molecular|SNPs|Chromosome Mapping|Ethnic Groups|Slc37a2 protein, human|Antiporters 52 PTPRM 31900385 Oncogenesis 2020 PMC6949220 10.1038/s41389-019-0187-2 0 0 0 98 Humans|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|*Receptor, mu|*Lung Cancer|Phosphorylation|Signal Transduction|Apoptosis|Cell Proliferation|Cell Line, Tumor|Protein Tyrosine Phosphatase|Receptor Protein Tyrosine Phosphatase mu|Protein Binding|PTPRM protein, human 52 PURG 32457471 Nat Commun 2020 PMC7250929 10.1038/s41467-020-16341-2 0 0 0 44 *Temperature|*Computer Simulation|Protein Structure, Secondary|Thermodynamics|Enzyme Stability|Cold Temperature|Entropy|Catalysis|Models, Molecular|Heat 36 PVT1 32664121 Medicine (Baltimore) 2020 10.1097/MD.0000000000021059 0 0 0 86 Humans|*RNA, Long Noncoding|*Up-Regulation|*Plasmacytoma|*Urinary Bladder Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Neoplasm Staging|Biomarkers, Tumor|*Transcriptional Activation|Lymphatic Metastasis|*Translocation, Genetic|Neoplasm Grading|*Neoplasms, Plasma Cell 464 PVT1 32655815 Am J Transl Res 2020 PMC7344089 0 0 0 86 Humans|Female|*RNA, Long Noncoding|*RNA, Micro|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Movement|Cell Line, Tumor|FOXM1 Protein|Whn protein|Forkhead Transcription Factors|Signal Transduction|Binding Sites|FOXM1 protein, human|MIRN370 microRNA, human 464 PVT1 32624708 Cancer Cell Int. 2020 PMC7330980 10.1186/s12935-020-01363-z 0 0 0 86 Humans|Male|*RNA, Long Noncoding|*Prostate|*Prostate Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Disease Progression|Cell Line, Tumor|Apoptosis|*Neoplastic Processes|KIF23 protein, human|Microtubule-Associated Proteins 464 PVT1 32614682 Br. 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Sci. 2020 10.1080/09674845.2020.1765459 0 0 0 86 *RNA, Long Noncoding|*Lupus Erythematosus, Systemic|*Lupus Erythematosus, Discoid|*Biomarkers|Lupus Nephritis|Case-Control Studies|*Erythema|Severity of Illness Index 464 PVT1 32612361 Breast Cancer (Auckl) 2020 PMC7309340 10.1177/1178223420934447 0 0 0 86 Humans|Neoplasm Recurrence, Local|Triple-Negative Breast Cancer|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|Cell Proliferation|*Gene Expression|Signal Transduction|Cell Cycle Proteins 464 PVT1 32602581 Mol Oncol 2020 10.1002/1878-0261.12754 0 0 0 86 Humans|*Nonsense Mediated mRNA Decay|*Tumor Necrosis Factor-alpha|*Apoptosis|RNA Helicases|Carrier Proteins|Signal Transduction|Protein Binding|RNA, Messenger|HeLa Cells|3'-(1-butylphosphoryl)adenosine|*Complement Factor B|RNA, Long Noncoding|SMG7 protein, human|CYLD protein, human|Deubiquitinating Enzyme CYLD 464 PVT1 32572930 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202006_21531 0 0 0 86 Humans|*Coronary Artery Disease|*RNA, Long Noncoding|Coronary Angiography|Risk Factors|Severity of Illness Index 464 PVT1 32562719 Brain Res. Bull. 2020 10.1016/j.brainresbull.2020.06.006 0 0 0 86 Mice|Animals|*RNA, Long Noncoding|*Plasmocytoma|*Glioma|*Up-Regulation|*Apoptosis|*Transcriptional Activation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Brain Neoplasms|Cell Line, Tumor|Signal Transduction|Mice, Nude|*Translocation, Genetic|Mirn128 microRNA, mouse 464 PVT1 32557622 J. Cell. Physiol. 2020 10.1002/jcp.29881 0 0 0 86 Humans|PVT1 long-non-coding RNA, human|*RNA, Long Noncoding|*Stomach Neoplasms|Epithelial-Mesenchymal Transition|MicroRNAs|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Snail Family Transcription Factors|Cell Migration|Down-Regulation|Cell Proliferation|Cell Line, Tumor|Lymphatic Metastasis 464 PVT1 32499447 Aging (Albany NY) 2020 PMC7346024 10.18632/aging.103268 0 0 0 86 *RNA, Long Noncoding|*Exosomes|*Vesicle-Associated Membrane Protein 3|*Plasmocytoma|*Pancreatic Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Upregulation|Cell Line, Tumor|Tumorigenesis|*Translocation, Genetic|Transcriptional Activation 464 PVT1 32471990 Nat Commun 2020 PMC7260243 10.1038/s41467-020-16434-y 0 0 0 86 Humans|*Multiple Myeloma|*Gene Fusions|Chromosomal Translocations|High-Throughput Nucleotide Sequencing|Gene Expression Profiling|FGFR3 protein, human|Receptor, Fibroblast Growth Factor, Type 3|In Situ Hybridization, Fluorescence|Whole Exome Sequencing 464 PVT1 32454150 Neurosci. Lett. 2020 10.1016/j.neulet.2020.135058 0 0 0 86 Humans|*Diabetic Neuropathies|Miat long non-coding RNA|Long Non-Coding RNA|*Non-Coding RNA|MicroRNAs|Diabetes Mellitus 464 PVT1 32441301 Biosci. Rep. 2020 PMC7295634 10.1042/BSR20200800 0 0 0 86 Humans|Female|*RNA, Long Noncoding|*Plasmocytoma|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Proliferation|Cell Movement|Cell Line, Tumor|Apoptosis|Signal Transduction|*Translocation, Genetic|MIRN543 microRNA, human 464 PVT1 32428696 Gene 2020 10.1016/j.gene.2020.144775 0 0 0 86 Humans|PVT1 long-non-coding RNA, human|*RNA, Long Noncoding|*Myocytes, Cardiac|*Beclin-1|*Autophagy|*Hypoxia|Apoptosis|Myocardial Reperfusion Injury|MicroRNAs|Cell Hypoxia|Cell Survival|*Protective Agents|Gene Knockdown Techniques|*Cell Death|MIRN186 microRNA, human 464 PVT1 32407172 Cancer Biother. Radiopharm. 2020 10.1089/cbr.2019.3342 0 0 0 86 464 PVT1 32406010 Clin Transl Oncol 2020 10.1007/s12094-020-02360-4 0 0 0 86 Humans|*RNA, Long Noncoding|*Plasmocytoma|*Leukemia, Myeloid, Acute|*Translocation, Genetic|*Cell Differentiation|Gene Expression Regulation, Leukemic|Cell Proliferation|Downregulation|locked nucleic acid|Oligonucleotides|*Bone Marrow Cells|Apoptosis|Upregulation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|RNA Interference|Cell Cycle Control|*Neoplasms, Plasma Cell 464 PVT1 32385030 Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2020 10.3881/j.issn.1000-503X.11395 0 0 0 86 464 PVT1 32368310 J Cancer 2020 PMC7196268 10.7150/jca.40421 0 0 0 86 Humans|*Carcinoma, Renal Cell|*RNA, Long Noncoding|Kidney Neoplasms|Prognosis|Kaplan-Meier Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Proportional Hazards Model|Downregulation|Up-Regulation|Carcinogenesis|Risk Factors|Cohort Studies 464 PVT1 32358016 G3 (Bethesda) 2020 10.1534/g3.120.401291 0 0 0 86 Humans|Male|*Plasmocytoma|*Prostate Cancer|Prostate|*Chromosomal Translocation|RNA, Long Noncoding|Exons|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Alleles|Cell Movement|*Gene Rearrangement|*Neoplasms, Plasma Cell|Cell Differentiation 464 PVT1 32342557 J. Clin. Lab. Anal. 2020 10.1002/jcla.23346 0 0 0 86 Humans|PVT1 long-non-coding RNA, human|*RNA, Long Noncoding|*Disease Progression|*Chronic Obstructive Pulmonary Disease|*Biomarkers|Cytokines|MicroRNAs|Severity of Illness Index|Inflammation|Case-Control Studies 464 PYHIN1 32102850 J. Biol. Chem. 2020 PMC7135979 10.1074/jbc.RA119.011400 1 0 0 57 Humans|Animals|*Cytokines|DNA Viruses|Phosphoproteins|Nuclear Proteins|Signal Transduction|DNA, Viral|Immunity, Innate|Interferon-beta|*Cells, Epithelial|Gene Expression|PYHIN1 protein, human 20 PYY3 32667131 Chembiochem 2020 10.1002/cbic.202000266 0 0 0 0 peptide YY (3-36)|*Peptide YY|*Tissue Distribution|*Peptide Fragments|*Single Photon Emission Computed Tomography Computed Tomography|Eating|Peptide Hormones|*Ions|*Metals 181 PYY3 32572709 Hormones (Athens) 2020 10.1007/s42000-020-00221-x 0 0 0 0 *Fasting|Peptide YY|Appetite|Feeding Behavior|Eating|Ghrelin 181 PYY3 32516384 Endocrinology 2020 10.1210/endocr/bqaa093 0 0 0 0 Rats|Animals|*GLP 1|Quality of Life|Glucagon-Like Peptide-1 Receptor|*Obesity|*Hyperphagia|Receptors, Glucagon|Eating|Venoms|Exenatide|Body Weight|Diet, High-Fat|Weight Loss|Reward|Rats, Sprague-Dawley|Motivation|Signal Transduction 181 PYY3 32166384 Eur J Nutr 2020 10.1007/s00394-020-02210-7 0 0 0 0 *Peptide YY|Anorexia Nervosa|peptide B|Leptin|Body Mass Index 181 RAD54B 32354124 Cancers (Basel) 2020 PMC7281129 10.3390/cancers12051101 0 0 0 120 Humans|*Melanoma|*Immunotherapy|Germ-Line Mutation|*Immunologic Factors|Genetic Predisposition to Disease|Biomarkers, Tumor|*Neoplasms, Second Primary|*Germ Line 67 RAP1GDS1 32431071 Ann Clin Transl Neurol 2020 PMC7318102 10.1002/acn3.51059 0 0 0 152 Humans|*Intellectual Disability|RAP1GDS1 protein, human|*Guanine Nucleotide Exchange Factor|RNA Splice Sites|Mutations|Amino Acid Sequence|Pedigree|Small GTPases|*Speech Delay 48 RAP1GDS1 32019878 Proc. 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U.S.A. 2020 PMC7035473 10.1073/pnas.1914153117 0 0 0 152 Humans|Mice|Animals|Carcinoma, Non-Small-Cell Lung|Lung Cancer|*Isoforms|*Oncogenes|Small GTPases|*Oncogenesis|Guanine Nucleotide Exchange Factors|Protein Prenylation|Amino Acid Sequence|Protein Binding|rhoA GTP-Binding Protein|Guanosine Triphosphate|RNA Splicing 48 rap2a 32606605 Drug Des Devel Ther 2020 PMC7306576 10.2147/DDDT.S249557 0 0 0 251 Humans|*Metformin|*Diabetes Mellitus, Type 1|*Insulin Resistance|*Tumor Suppressor Protein p53|rap GTP-Binding Proteins|Cell Movement|Cell Line, Tumor|RAP2A protein, human 128 rap2a 32194636 Front Genet 2020 PMC7063470 10.3389/fgene.2020.00180 0 0 0 251 *Urinary Bladder Neoplasms|*Up-Regulation|*Disease Progression|Gene Expression Regulation, Neoplastic|RNA, Long Noncoding|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor|*Transcriptional Activation|*Neoplastic Processes|*Bladder|Tumorigenesis|Apoptosis|Cell Transformation, Neoplastic 128 rap2a 32024547 J Ovarian Res 2020 PMC7003402 10.1186/s13048-020-0611-4 0 0 0 251 Humans|Female|Mice|Animals|*Insulin|*Granulosa Cells|MicroRNAs|*Insulin, Regular, Human|Polycystic Ovary Syndrome|Cell Proliferation|Apoptosis|Ovary|Cells, Cultured|RAP2A protein, human|rap GTP-Binding Proteins|Mirn140 microRNA, human|Rap2a protein, mouse 128 rap2a 31912905 J. Cell. Physiol. 2020 10.1002/jcp.29443 0 0 0 251 neratinib|*Phosphatidylinositol 3-Kinases|*MAP Kinase Signaling System|MAP4K4 protein, human|Protein-Serine-Threonine Kinases|*Signal Transduction|*Quinolines|LATS1 protein, human|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|Intracellular Signaling Peptides and Proteins|*Autophagy|Phosphorylation|Adaptor Proteins, Signal Transducing|Pancreatic Cancer|Inhibitors, HDAC|Transcription Factors|Beclin1 128 rap2a 31897147 Oncol Lett 2020 PMC6923840 10.3892/ol.2019.11086 0 0 0 251 Humans|*Cisplatin|*Stomach Neoplasms|Cell Proliferation|Drug Resistance, Neoplasm|Antineoplastic Agents|Apoptosis|Cell Line, Tumor|Proto-Oncogene Proteins c-akt|Cell Movement|Gene Expression Regulation, Neoplastic|Down-Regulation|Signal Transduction|*Stomach|RAP2A protein, human|rap GTP-Binding Proteins 128 RAPGEF6 32339978 Eur. J. Cancer 2020 10.1016/j.ejca.2020.03.002 0 0 0 96 Humans|*Pleura|Mesothelioma, Malignant|*Mesothelioma|Pleural Neoplasms|*Lung Neoplasms|Prognosis|Treatment Outcome|*Genomics|Mutation 25 RASGEF1B 32171250 BMC Genet. 2020 PMC7071762 10.1186/s12863-020-0837-6 0 0 0 25 Cattle|Animals|Genome-Wide Association Study|*Body Size|Breeding|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Phenotype|Haplotypes|Body Weight|Genomics|Models, Statistical 28 RAX2 32152126 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7104260 10.1073/pnas.1912505117 1 0 0 14 *Cues|Saccharomyces cerevisiae Proteins|*Pheromones|Saccharomyces cerevisiae|Cell Polarity|Chemotaxis|Cell Division|Signal Transduction 25 RAX2 32144893 FEBS Open Bio 2020 PMC7137802 10.1002/2211-5463.12832 0 0 0 14 Animals|*Genes, Homeobox|Phylogeny|Vertebrates|Homeodomain Proteins|Ctenophora|Synteny|Cnidaria|Transcription Factors|Evolution, Molecular|Placozoa|Genomes|Eye Proteins 25 RAX2 32015336 Cell Death Dis 2020 PMC6997171 10.1038/s41419-020-2267-9 0 0 0 14 Humans|Adult|*Glioblastoma|BDNF protein, human|*Brain-Derived Neurotrophic Factor|RNA, Long Noncoding|Glioma|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Cell Proliferation|MicroRNAs|*RNA-Binding Proteins|Apoptosis|Cell Movement|Cell Line, Tumor|*Disease Progression|Downregulation|mRNA Decay|DLG5 protein, human|Membrane Proteins 25 RBM20 32276354 Genes (Basel) 2020 PMC7230170 10.3390/genes11040402 0 0 0 136 Humans|Animals|*Ribonucleoproteins|*Cardiovascular Diseases|Alternative Splicing|Polypyrimidine Tract-Binding Protein|Connectin|Exons|RNA-Binding Proteins|Cardiomyopathy, Dilated|Isoforms|RNA Splicing|Myocytes, Cardiac|Mutations|PTBP1 protein, human|Heterogeneous-Nuclear Ribonucleoproteins 88 RBM20 32187365 Nucleic Acids Res. 2020 PMC7192616 10.1093/nar/gkaa168 1 0 0 136 Mice|Animals|*RNA Recognition Motif|*Nucleotide Motifs|*RNA Splicing|Connectin|Exon|Alternative Splicing|RNA Precursors|RNA-Binding Proteins|Myocytes, Cardiac|Protein Isoforms|RNA|Binding Sites|Mutations|RBM20 protein, mouse 88 RBM20 32116740 Front Physiol 2020 PMC7025574 10.3389/fphys.2020.00015 0 0 0 136 Humans|Rats|Animals|TTN protein, human|*Connectin|*Heart Ventricles|*Protein Isoforms|Muscle Proteins|Myocardium|Myofibrils|Hearts|Heart Failure|Exercise Tolerance 88 RBM20 32056050 Heart Fail Rev 2020 10.1007/s10741-020-09933-z 1 0 0 136 Humans|*Cardiomyopathy, Dilated|*Arrythmia|Sudden Cardiac Death|Cardiomyopathy|Arrhythmogenic Right Ventricular Dysplasia|Ventricular Dysfunction, Left|Electrocardiogram|Phenotypes|Heart Failure|Left Ventricle|Mutation|Genotypes|Risk Assessment|Risk Factors 88 RBM20 32041989 Sci Rep 2020 PMC7010767 10.1038/s41598-020-58984-7 0 0 0 136 Humans|*Cardiomyopathy, Dilated|Prospective Studies|*Genotype-Phenotype Correlations|Connectin|Heterozygote|Phenotype|Pedigree|Cardiomyopathies|Sequencing, Next-Generation|Mutation|Cardiac Transplantation|Proportional Hazards Models 88 RBM20 31970460 Herz 2020 10.1007/s00059-019-04883-1 0 0 0 136 *Sudden Cardiac Death|Sequencing, Whole Exome|Exome|Mutations|Phenotype|Pedigree|Ryanodine Receptor Calcium Release Channel|Heterozygote|Heart|AKAP9 protein, human|Cytoskeletal Proteins|Mutation, Missense|A Kinase Anchor Proteins 88 RBM24 32547083 Onco Targets Ther 2020 PMC7247600 10.2147/OTT.S246274 0 0 0 140 Humans|Male|*RNA, Long Noncoding|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Prostate|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Apoptosis|Prostate Cancer|Disease Progression|*Cell Transformation, Neoplastic|HAND2 protein, human|Basic Helix-Loop-Helix Transcription Factors|RBM24 protein, human|RNA-Binding Proteins 41 RBM24 32376900 Sci Rep 2020 PMC7203132 10.1038/s41598-020-64667-0 0 0 0 140 Mice|Animals|*Sarcomeres|TTN protein, human|Titin|Myocardium|Cardiomyocytes|Myofilament|Alternative Splicing|RNA-Binding Proteins|Muscle, Skeletal|Mice, Knockout|Protein Isoforms 41 RBM24 32170011 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7132282 10.1073/pnas.1917922117 0 0 0 140 Animals|*Messenger RNA|RNA Binding Protein|Lens, Crystalline|Cataract|Transcription Factors|Cytoplasm|Zebrafish 41 RBMS3 32627033 Oncol. Rep. 2020 PMC7251710 10.3892/or.2020.7594 0 0 0 104 Humans|*Gallbladder Neoplasms|Prognosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Biomarkers, Tumor|mRNA|Cell Line, Tumor|Neoplasm Staging|Cell Movement|Neovascularization, Pathologic|RBMS3 protein, human|Trans-Activators|RNA-Binding Proteins 41 RBMS3 32176034 Medicine (Baltimore) 2020 10.1097/MD.0000000000019086 0 0 0 104 Humans|*Small Cell Lung Carcinoma|*Computational Biology|MIRN92 microRNA, human|*MicroRNAs|MIRN1290 microRNA, human|MIRN1 microRNA, human|MIRN144 microRNA, human|Gene Expression Regulation, Neoplastic|Downregulation|Upregulation|Gene Expression Profiling|*Lung|Gene Regulatory Networks|Cell Movement|Lung Neoplasms|Prognosis|Signal Transduction|NEDD9 protein, human 41 RBMS3 32016951 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202001_20023 0 0 0 104 *Intervertebral Disc Degeneration|Nucleus Pulposus|*Wnt Signaling Pathway|Intervertebral Disc|beta Catenin|*Catenins|Extracellular Matrix|Cells, Cultured 41 RBMS3 31987045 J. Exp. Clin. Cancer Res. 2020 PMC6986051 10.1186/s13046-019-1509-0 0 0 0 104 TWIST1 protein, human|*Twist-Related Protein 1|*RNA Binding Protein|*Nuclear Proteins|Trans-Activators|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|RNA, Messenger 41 RC3H1 32446391 Biochem. Biophys. Res. Commun. 2020 10.1016/j.bbrc.2020.04.008 0 0 0 430 Humans|Female|*Uterine Cervical Neoplasms|*Signal Transduction|NF kB|CCND1 protein, human|Cyclin D1|Cell Cycle|Cell Proliferation|Cell Line, Tumor|*Cell Division|Transcriptional Activation|RNA, Small Interfering|RC3H1 protein, human|RNA-Binding Proteins|Ubiquitin-Protein Ligases 71 REG1A 32149050 World J Clin Cases 2020 PMC7052547 10.12998/wjcc.v8.i4.658 0 0 0 2130 *Transcriptome Analysis|*Stomach Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Ontology|Transcriptome|MicroRNAs|Computational Biology|Protein Interaction Maps|Biomarkers, Tumor|mRNA|Carcinoma, Signet Ring Cell 307 REG1A 32121033 J Clin Med 2020 PMC7141221 10.3390/jcm9030639 1 0 0 2130 Humans|Diabetic Nephropathy|Albuminuria|*Biomarkers|*Kidney|*Early Diagnosis|CDH1 protein, human|*E Cadherin|Diabetes Mellitus, Type 2|Antigens, CD|Specificity|Proteomics|APOA1 protein, human|Apolipoprotein A-I|Enzyme-Linked Immunosorbent Assay|REG1A protein, human|Lithostathine 307 REG1B 32324737 PLoS Negl Trop Dis 2020 PMC7200013 10.1371/journal.pntd.0008243 0 0 0 24 Child|Humans|*Nutritional Status|*Helicobacter Infections|*Helicobacter pylori|Bangladesh|*Feces|*Intestine, Small|*Biomarkers|Neopterin|Intestinal Diseases|SERPINA1 protein, human|alpha 1-Antitrypsin|Growth Disorders|Myeloperoxidase|Inflammation|Intestinal Mucosa 36 REG1B 32149050 World J Clin Cases 2020 PMC7052547 10.12998/wjcc.v8.i4.658 0 0 0 24 *Transcriptome Analysis|*Stomach Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Ontology|Transcriptome|MicroRNAs|Computational Biology|Protein Interaction Maps|Biomarkers, Tumor|mRNA|Carcinoma, Signet Ring Cell 36 RELT 32110668 World J Clin Cases 2020 PMC7031839 10.12998/wjcc.v8.i3.568 0 0 0 87 *Liver Transplantation|*Reoperation|Portal Vein|*Liver|Hepatic Artery|*Biliary Tract|Thrombosis|Stenosis|Postoperative Complications 46 RELT 32090861 Tuberculosis (Edinb) 2020 10.1016/j.tube.2020.101900 0 0 0 87 Humans|*Mycobacterium tuberculosis|*Macrophages|*Autophagy|Tuberculosis|Cytokines|Inflammation|Downregulation|Upregulation 46 RELT 32065433 Transpl. Int. 2020 PMC7318636 10.1111/tri.13596 1 0 0 87 Humans|*Retrospective Studies|*Reoperation|Donors|Graft Survival|Liver Transplantations|Tissue and Organ Procurement|Donor Selection|Brain Death|*Liver|Postoperative Complications|Treatment Outcome|Strictures|Netherlands 46 RELT 32052416 Clin. Genet. 2020 PMC7216828 10.1111/cge.13721 1 0 0 87 Humans|Child|*Amelogenesis Imperfecta|RELT|Homozygote|Genes, Recessive|Pedigree|Exon|Mutations|Mutation, Missense|Phenotype|Ameloblasts|Haplotype|Microsatellite 46 RETNLB 32253406 Food Funct 2020 10.1039/d0fo00064g 0 0 0 201 *Goblet Cells|*Lactose|*Glycosides|*Oligosaccharides|Prebiotics|Galactose|beta-Galactosidase|Sulfotransferases|*Cardiac Glycosides|Mucus|*Genetic Linkage 152 RETNLB 32235004 Aging (Albany NY) 2020 PMC7185108 10.18632/aging.102979 0 0 0 201 *Prognosis|Early Detection of Cancer|*Colorectal Cancer|*Colonic Neoplasms|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Databases, Genetic|*Screening|Transcriptome|Computational Biology 152 RETNLB 32045592 Life Sci. 2020 10.1016/j.lfs.2020.117419 0 0 0 201 Humans|*Pulmonary Artery|*Smooth Muscle Cells|*Hypoxia|Muscle, Smooth, Vascular|Familial Primary Pulmonary Hypertension|Hypertension, Pulmonary|Cell Proliferation|Cell Hypoxia|Apoptosis 152 RGN 32602419 Int. 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Biol. 2020 10.1080/09553002.2020.1787546 0 0 0 1823 Mice|Animals|romiplostim|*Receptors, Thrombopoietin|*Proteomics|*Thrombopoietin|*Receptors, Fc|*Recombinant Fusion Proteins|*Total Body Irradiation|Radiation-Protective Agents|Mice, Inbred C57BL|*Hematologic Agents|Dose-Response Relationship, Radiation|Ionizing Radiation 638 RGN 32580714 BMC Health Serv Res 2020 PMC7313105 10.1186/s12913-020-05143-3 0 0 0 1823 Humans|*Pilot Projects|Cancer|Patient Care Team|*Interdisciplinary Studies|Interprofessional Relations|Practice Patterns, Physicians'|Decision Making 638 RGN 32514242 BMC Nurs 2020 PMC7254762 10.1186/s12912-020-00436-8 0 0 0 1823 Humans|*Psychometrics|Clinical Competence 638 RGN 32505718 Fish Shellfish Immunol. 2020 10.1016/j.fsi.2020.06.002 0 0 0 1823 Animals|*Flounder|*Novirhabdovirus|Rhabdoviridae Infections|*Glycoprotein|Fish Diseases|Fish Proteins|glycoprotein B, Simplexvirus|Viral Envelope Proteins|Vaccination 638 RGN 32459753 Plast Surg Nurs 2020 10.1097/PSN.0000000000000299 0 0 0 1823 Humans|*Alopecia|*Platelet Rich Plasma|Combined Modality Therapy 638 RGN 32439509 Fish Shellfish Immunol. 2020 10.1016/j.fsi.2020.05.002 0 0 0 1823 Animals|*Crassostrea|*Hemocytes|*Apoptosis|Sequence Alignment|Immunity, Innate|Amino Acid Sequence|Gene Expression Profiling|ferrous fumarate|*Ferrous Compounds|Lipopolysaccharides|Phylogeny|Cells, Cultured 638 RGN 32381523 J Neurointerv Surg 2020 10.1136/neurintsurg-2020-015953 0 0 0 1823 Alberta|*Stroke|*Reperfusion|Thrombectomy|Brain Ischemia|Endovascular Procedures|Treatment Outcome|Tomography, X-Ray Computed 638 RGN 32335485 Waste Manag 2020 10.1016/j.wasman.2020.04.033 0 0 0 1823 *Aluminum|*Recycling|Waste Management|*Static Electricity|Copper|Particle Size 638 RGN 32252479 Cells 2020 PMC7226760 10.3390/cells9040869 1 0 0 1823 Dystrophin|*Genetic Vectors|Duchenne Muscular Dystrophy|Gene Editing|CRISPR-Cas Systems|RNA, Guide|Genetic Therapy|Adenoviridae|Myoblasts|Mutations 638 RGN 32213392 Chemosphere 2020 10.1016/j.chemosphere.2020.126531 0 0 0 1823 illite|*Minerals|Geologic Sediments|Clay|Environmental Monitoring|Water Pollutants, Chemical|*Surface Properties|Adsorption|Kaolinite|Aluminum Silicates|Cations 638 RGN 32138383 Int J Environ Res Public Health 2020 PMC7084375 10.3390/ijerph17051651 0 0 0 1823 Humans|Siberia|*Aerosols|Air Microbiology|Fungi|Environmental Monitoring|Bacteria 638 RGN 32124840 Arch. 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Urol. 2020 0 0 0 1823 Male|Humans|Female|Intermittent Urethral Catheterization|Neurogenic Bladder Disorder|Urinary Tract Infections|*Catheter|Spinal Cord Injuries|*Hydrophobic and Hydrophilic Interactions|Self Care|Spain 638 RGN 32115435 J Neurointerv Surg 2020 10.1136/neurintsurg-2019-015754 0 0 0 1823 *Robotic Surgical Procedures|*Feasibility Studies|*Stents|*Carotid Artery, Common|Carotid Stenosis|Carotid Artery, Internal|*Robotics|Treatment Outcome 638 RGN 32102074 Plast Surg Nurs 2020 10.1097/PSN.0000000000000285 0 0 0 1823 Humans|Female|Male|Diffuse alopecia|Alopecia Areata 638 RGN 32069989 Molecules 2020 PMC7070259 10.3390/molecules25040816 1 0 0 1823 Humans|*Colicins|*Lung Cancer|*Apoptosis|Carcinoma, Non-Small-Cell Lung|*Integrins|Apoptosis Regulatory Proteins|Cell Line, Tumor|Cell Survival|Cell Proliferation|Signal Transduction|Downregulation 638 RGN 32032872 Chemosphere 2020 10.1016/j.chemosphere.2020.126002 0 0 0 1823 *Mercury|*Pseudomonas|Slovenia|Methylmercury Compounds|Soils|Environmental Monitoring|Soil Pollutants|*Bacteria|XANES Spectroscopy|Operon 638 RGN 32015181 J Neurointerv Surg 2020 10.1136/neurintsurg-2019-015347 0 0 0 1823 Thrombectomy|Stroke|Brain Ischemia|Cerebral Angiography|Stents|Treatment Outcome|Retrospective Studies|Catheter 638 RGN 32006245 Reprod Sci 2020 10.1007/s43032-020-00146-1 0 0 0 1823 Humans|Female|ulipristal acetate|*Endometriosis|*Norpregnadienes|Endometrium|progesterone receptor B|Progesterone Receptor|Leiomyoma|Uterine Neoplasms|Amenorrhea 638 RGN 32000239 Dimens Crit Care Nurs 2020 10.1097/DCC.0000000000000407 0 0 0 1823 Humans|*Students, Nursing|*Internship and Residency|Education, Nursing, Baccalaureate|*Inservice Training|Clinical Competence|Attitude of Health Personnel|Qualitative Research|Ireland 638 RGN 31972102 Br J Nurs 2020 10.12968/bjon.2020.29.2.S27 0 0 0 1823 Humans|*Venipuncture|Jugular Veins|Catheterization, Central Venous|Central Venous Catheters|*Liver Disease|*Digestive System Diseases|*Vascular Diseases 638 RHBDF1 32646486 Genome Biol. 2020 PMC7350591 10.1186/s13059-020-02086-0 0 0 0 79 Mice|Animals|*Exons|*Gene Targeting|RNA, Guide|Gene Editing|CRISPR-Cas Systems|CRISPR|Alleles|Zygotes 30 RHBDF1 32103528 FASEB J. 2020 PMC7316530 10.1096/fj.201902649R 0 0 0 79 ADAM17 protein, human|*ADAM-17|RHBDF2 protein, human|*Carrier Proteins|*Cell Membrane|TYRP1 protein, human|*Membrane Glycoproteins|ADAM Proteins|Membrane Proteins|EGFR protein, human|Receptor, EGF|Signal Transduction|BTC protein, human|Betacellulin|Fibroblasts|*Protein Domains 30 RHBDF1 32060096 J. 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Immunopharmacol. 2020 10.1016/j.intimp.2020.106735 0 0 0 114 Humans|Female|*Prognosis|*Endometrial Cancer|Biomarkers, Tumor|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|CD8-Positive T-Lymphocytes|Immunotherapy|S100A14 protein, human|Calcium-Binding Proteins 69 S100A14 32606808 Onco Targets Ther 2020 PMC7321690 10.2147/OTT.S249973 0 0 0 114 *Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Cancer|*Upregulation|*Disease Progression|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Transcriptional Activation 69 S100A14 32555330 Oncogene 2020 10.1038/s41388-020-1363-8 0 0 0 114 Humans|*Nasopharyngeal Carcinoma|*NF kB|*Interleukin 1 Receptor Associated Kinase 1|*Signal Transduction|Epithelial-Mesenchymal Transition|Nasopharyngeal Neoplasms|Proto-Oncogene Proteins c-akt|Cell Movement|*Neoplastic Processes|Cell Line, Tumor|Downregulation|S100A14 protein, human|Calcium-Binding Proteins|IRAK1 protein, human 69 S100A14 32483447 Theranostics 2020 PMC7255029 10.7150/thno.46553 0 0 0 114 69 S100A14 32483412 Theranostics 2020 PMC7255008 10.7150/thno.42087 0 0 0 114 69 S100A14 32444848 Sci Rep 2020 PMC7244564 10.1038/s41598-020-65584-y 0 0 0 114 *Perceptron|*Proteins|Machine Learning|*Neoplastic Processes|*Immunotherapy|Amino Acid Sequence|Cancer|Receiver Operating Characteristics|RNA 69 S100A14 32244462 Nanomaterials (Basel) 2020 PMC7221965 10.3390/nano10040649 1 0 0 114 Humans|nickel monoxide|*Nickel|*Lung|DNA Damage|Metal Nanoparticles|*Transcriptome Profiling 69 S100A14 32202693 Head Neck 2020 10.1002/hed.26140 0 0 0 114 *Carcinoma, Squamous Cell|*Mouth Neoplasms|Prognosis|Cell Line, Tumor|Calcium-Binding Proteins|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Neoplastic Processes|*Cell Differentiation 69 S100A16 32411773 Ann Transl Med 2020 PMC7214889 10.21037/atm.2020.04.38 0 0 0 181 *Carcinoma, Non-Small-Cell Lung|*Prognosis|*Lung Cancer|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Databases, Genetic 46 S100A16 32256978 Oncotarget 2020 PMC7105160 10.18632/oncotarget.27511 0 0 0 181 Humans|Male|Polycomb Repressive Complex 2|DNA-Binding Proteins|Pc protein, Drosophila|Drosophila Proteins|Polycomb-Group Proteins|Histones|Polycomb Repressive Complex 1|Protein Isoforms|*Prostatic Neoplasms|Cell Proliferation 46 S100A16 32094322 Cell Death Dis 2020 PMC7039973 10.1038/s41419-020-2337-z 0 0 0 181 *Fibrosis|*Kidney Diseases|Epithelial-Mesenchymal Transition|Ureteral Obstruction|Kidney Tubules|Transforming Growth Factor beta1|Cells, Epithelial|*Calcium-Binding Proteins|Cell Line|Fibroblasts|*Cytoskeletal Proteins|Cytoskeletons|Myosins 46 S100A16 32021296 Onco Targets Ther 2020 PMC6974148 10.2147/OTT.S221276 0 0 0 181 Humans|Male|*Messenger RNA|*Prostate|*Computational Biology|Prostate Cancer|Antigens, Neoplasm|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 46 S100A16 31894756 Med. 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Diagn. 2020 10.1002/pd.5781 0 0 0 94 Pregnancy|Female|Humans|*Prospective Studies|*Exome|*Diagnostic Tests, Routine|*Ultrasonography, Prenatal|*Whole Exome Sequencing|*Abnormalities, Multiple|Fetuses|Prenatal Diagnosis|Genetic Testing 84 SAMD9 32619790 Cancer Genet 2020 10.1016/j.cancergen.2020.06.002 0 0 0 94 Humans|Child|Myelodysplastic Syndromes|*Cytogenetic|Leukemia, Myeloid, Acute|SAMD9 protein, human|Mutation|Chromosome 7, monosomy|Chromosome Deletion|Bone Marrow|Intracellular Signaling Peptides and Proteins|Adrenal Insufficiency|Phenotype|Chromosomes, Human, Pair 7|Cytogenetic Analysis 84 SAMD9 32266167 Front Cell Infect Microbiol 2020 PMC7098914 10.3389/fcimb.2020.00116 0 0 0 94 Humans|*Vaccinia virus|*Vaccinia|SAMD9 protein, human|Viral Proteins|*Antiviral Agents|Virus Replication|Host Range|Intracellular Signaling Peptides and Proteins|HeLa Cells|*Genes, Regulator 84 SAMD9 32194975 Hum Genome Var 2020 PMC7057985 10.1038/s41439-020-0091-5 0 0 0 94 Myelodysplastic Syndromes|Hypoadrenocorticism, Familial|Adrenal Insufficiency|*Mutation, Missense|Phenotypes|Intracellular Signaling Peptides and Proteins|Mutation 84 SAMD9 32168470 Reproduction 2020 10.1530/REP-19-0464 0 0 0 94 Pregnancy|Cattle|Animals|Female|*Corpus Luteum|*Endometrium|*Embryo, Mammalian|Embryo Transfer|Embryo Implantation|Uterus|Estrous Cycle|Blastocysts|Progesterone|Breeding|Transcriptome 84 SAMD9 32106287 J. 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Lymphoma 2020 10.1080/10428194.2020.1719089 0 0 0 1118 *Myelodysplastic Syndrome|Leukemia, Myeloid, Acute|Mutations|Disease Progression 173 SETBP1 31989250 Ann. 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Cell. Mol. Med. 2020 PMC7077606 10.1111/jcmm.15023 2 0 0 234 *Diabetes Mellitus, Type 2|*Adipokine|*Obesity|WNT5A protein, human|Wnt-5a Protein|Insulin Resistance|*Coronary Heart Disease|Eye Proteins|Wnt Proteins|Membrane Proteins|*Anti-Inflammatory Agents|Adipocytes 269 SFRP5 31981630 Life Sci. 2020 10.1016/j.lfs.2020.117338 0 0 0 234 Humans|*Coronary Artery Disease|*Pericardium|*Adipose Tissue|Adipokines|WNT5A protein, human|*Wnt-5a Protein|Adipose Tissue, Subcutaneous|Obesity|mRNA|Biomarkers|Inflammation|SFRP5 protein, human|Eye Proteins|Membrane Proteins 269 SFRP5 31950540 Cell Biochem. Funct. 2020 10.1002/cbf.3486 0 0 0 234 Humans|MicroRNAs|Cell Proliferation|Fibroblasts|Downregulation|RNA Interference|ACTA2 protein, human|Actins|Up-Regulation|Collagen Type I|Fibrosis|*Heart|Myocardium|siRNA|Myocardial Infarction|Cells, Cultured|SFRP5 protein, human|Eye Proteins|Membrane Proteins 269 SFRP5 31890678 J Diabetes Metab Disord 2020 PMC6915239 10.1007/s40200-019-00461-8 2 0 0 234 Humans|Animals|WNT5A protein, human|*Wingless-Type MMTV Integration Site Family, Member 5A|*Diabetes Mellitus, Type 2|*Diabetic Nephropathies|*Biomarkers|Insulin Resistance|Wnt Proteins|Insulin|Eye Proteins|Membrane Proteins 269 SGCA 32576226 Orphanet J Rare Dis 2020 PMC7310488 10.1186/s13023-020-01445-1 0 0 0 379 Humans|*Limb Girdle Muscular Dystrophy|*Asian Continental Ancestry Group|Phenotypes|Mutation|*Cohort Studies|Muscle, Skeletal|Genotypes|Pentosyltransferases 116 SGCA 32528171 Genet. Med. 2020 10.1038/s41436-020-0840-3 0 0 0 379 Humans|*Exome|*Whole Exome Sequencing|Muscular Dystrophies, Limb-Girdle|Genetic Testing|Sequence Analysis, DNA|Mutation|*Muscle Weakness 116 SGCA 32281310 Mol Genet Genomic Med 2020 PMC7284024 10.1002/mgg3.1241 1 0 0 379 Humans|Infant|*Osteogenesis Imperfecta|*DNA Copy Number Variations|Type I Collagen|Mutations|Phenotype|Pedigree 116 SGCA 32071288 Cell Death Dis 2020 PMC7028923 10.1038/s41419-020-2332-4 0 0 0 379 Humans|Mice|Animals|cyanidin|*Dystrophy, Muscular|*Anthocyanins|Muscular Dystrophy, Animal|Muscle Fibers, Skeletal|Sarcoglycans|Muscle, Skeletal|Mice, Knockout|*Disease Progression 116 SGCA 31953240 Eur J Med Genet 2020 10.1016/j.ejmg.2020.103845 0 0 0 379 Humans|*Exome|*Whole Exome Sequencing|*Muscular Dystrophies|Muscular Dystrophies, Limb-Girdle|Phenotypes|Genetic Testing|Pedigree|Muscle Proteins|Mutation|Cohort Studies|DYSF protein, human|Dysferlin 116 SGCA 31937337 Orphanet J Rare Dis 2020 PMC6961257 10.1186/s13023-020-1296-x 0 0 0 379 Humans|*Founder Effect|Iran|Limb-girdle muscular dystrophy autosomal recessive|*Muscular Dystrophies, Limb Girdle|*Mutations|Sarcoglycans|Pedigree|Calpain|Muscle Proteins|Short Tandem Repeat|*Cohort Studies 116 SGCA 31931849 Orphanet J Rare Dis 2020 PMC6958675 10.1186/s13023-019-1291-2 1 0 0 379 Humans|*Glycogen Storage Disease Type II|*High-Throughput Nucleotide Sequencing|*Muscle Weakness|Latin America|Limb Girdle Muscular Dystrophy|Sequence Analysis, DNA|Mutation 116 SGCD 32163230 Mol Genet Genomic Med 2020 PMC7216806 10.1002/mgg3.1176 1 0 0 100 Humans|*Whole Exome Sequencing|*Gastroschisis|Genetic Association Studies|Exome|Pedigree|Genetic Predisposition to Disease|Heredity 88 SGCD 32060408 Lab. Invest. 2020 PMC7280178 10.1038/s41374-020-0406-7 0 0 0 100 Humans|Swine|Animals|*Sarcoglycans|*Cardiomyopathy|Dystrophin|Myocardium|Sarcolemma|Heart|Muscle, Skeletal|*Phenotype|Cytoskeletal Proteins 88 SGCD 32051389 Exp. Anim. 2020 10.1538/expanim.19-0118 0 0 0 100 Animals|Mice|*Transgenic Mouse|*Mice, Inbred C57BL|*Transgene|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|Genomics|Genome|Nanopore|Base Sequence 88 SGCD 31931849 Orphanet J Rare Dis 2020 PMC6958675 10.1186/s13023-019-1291-2 1 0 0 100 Humans|*Glycogen Storage Disease Type II|*High-Throughput Nucleotide Sequencing|*Muscle Weakness|Latin America|Limb Girdle Muscular Dystrophy|Sequence Analysis, DNA|Mutation 88 SH3PXD2B 31978614 Eur J Med Genet 2020 10.1016/j.ejmg.2020.103857 0 0 0 105 Humans|Child|Ter Haar syndrome|*Craniofacial Abnormalities|*Osteochondrodysplasias|*Heart Defects, Congenital|*Developmental Disabilities|*Phenotypes|Abnormalities, Multiple|Musculoskeletal Abnormalities|Megalocornea|Genetic Diseases, X-Linked|Hand Deformities, Congenital|Eye Diseases, Hereditary|Homozygote|Mutation|Adaptor Proteins, Signal Transducing 23 SHBG 32674116 J Appl Lab Med 2020 10.1093/jalm/jfaa028 0 0 0 3194 Female|Humans|*Transgender Persons|*Transsexualism|Testosterone|Oestradiol|Luteinizing Hormone|*Reference Values|Sex Hormone-Binding Globulin|Estrogens|Follicle Stimulating Hormone|Progesterone|Prolactin|Cohort Studies 8459 SHBG 32654174 Clin. Endocrinol. (Oxf) 2020 10.1111/cen.14283 0 0 0 3194 Male|Female|Humans|Prolactin Deficiency, Isolated|*Prolactin|*Depression|Sexual Dysfunction, Physiological|*Lactation Disorders|Dopamine Agonist|Surveys and Questionnaires 8459 SHBG 32652892 Mol Nutr Food Res 2020 10.1002/mnfr.201901253 0 0 0 3194 *Sex Hormone-Binding Globulin|*Adiponectin|*Caffeine|*Proto-Oncogene Proteins c-akt|*Upregulation|*Liver|*Adipose Tissue, White|Hepatocyte Nuclear Factor 4|*Transcriptional Activation 8459 SHBG 32644296 Andrology 2020 10.1111/andr.12861 0 0 0 3194 Male|Humans|*Obesity, Metabolically Benign|*Cross-Sectional Studies|Obesity|Metabolic Syndrome|Risk Factors|*Infertility|Sperm 8459 SHBG 32641273 J Am Med Dir Assoc 2020 10.1016/j.jamda.2020.05.005 0 0 0 3194 Male|Humans|Female|Aged|Aged, 80 and over|*Sarcopenia|*Cross-Sectional Studies|United Kingdom|*Biological Specimen Banks|Hand Strength|Geriatric Assessment|Absorptiometry, Photon|*Biomarkers 8459 SHBG 32620010 J. Clin. Endocrinol. Metab. 2020 10.1210/clinem/dgaa431 0 0 0 3194 Pregnancy|Female|Humans|*Prospective Studies|Diabetes Mellitus, Type 2|Alkanesulfonic Acids|Fluorocarbons|Caprylates|*Cohort Studies|Environmental Pollutants|Environmental Exposure|*Postpartum|Prenatal Exposure Delayed Effects|Linear Models 8459 SHBG 32610558 Genes (Basel) 2020 10.3390/genes11070721 0 0 0 3194 *Mendelian Randomization Analysis|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Risk Factors|Diabetes Mellitus, Type 2|Testosterone|Genetic Variation 8459 SHBG 32592042 Arch. Gynecol. Obstet. 2020 10.1007/s00404-020-05656-6 0 0 0 3194 Female|Humans|*Polycystic Ovary Syndrome|*Insulin Resistance|*Nutritional Status|Obesity|Insulin|Luteinizing Hormone|Follicle Stimulating Hormone|Body Mass Index|Sex Hormone-Binding Globulin|Blood Glucose|Testosterone 8459 SHBG 32589470 Genet Test Mol Biomarkers 2020 10.1089/gtmb.2019.0229 0 0 0 3194 8459 SHBG 32583294 Clin Drug Investig 2020 10.1007/s40261-020-00942-2 0 0 0 3194 Female|Humans|*Liraglutide|*Polycystic Ovary Syndrome|Double-Blind Method|Diabetes Mellitus, Type 2|Metformin|Obesity|Weight Reduction|Overweight|Body Weight|Glucagon-Like Peptide-1 Receptor|Hypoglycemic Agents|Body Mass Index|Prediabetes 8459 SHBG 32581113 Cancer Epidemiol. Biomarkers Prev. 2020 10.1158/1055-9965.EPI-20-0246 0 0 0 3194 *Cohort Studies|United Kingdom|*Biological Specimen Banks|*Cancers|*Gonadal Steroid Hormones|Sex Hormone-Binding Globulin|Estradiol|Testosterone|Postmenopause|Case-Control Studies|*Pancreas|*Brain 8459 SHBG 32576049 Endocr Pract 2020 10.4158/EP-2020-0153 0 0 0 3194 8459 SHBG 32574161 PLoS Med. 2020 PMC7310679 10.1371/journal.pmed.1003132 0 0 0 3194 Female|Humans|*Polycystic Ovary Syndrome|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Asian Continental Ancestry Group|Genotype|Case-Control Studies|European Continental Ancestry Group|*Clustering 8459 SHBG 32565962 Oncol Lett 2020 PMC7285803 10.3892/ol.2020.11549 0 0 0 3194 Humans|Male|Female|*Sex Hormone-Binding Globulin|*Healthy Volunteers|Testosterone|Pre-Menopause|Aging|MUC1 protein, human|Mucin-1 8459 SHBG 32562143 Hormones (Athens) 2020 10.1007/s42000-020-00219-5 0 0 0 3194 Female|Humans|*Polycystic Ovary Syndrome|*Metabolic Syndrome|*Sex Hormone-Binding Globulin|Insulin Resistance|Body Mass Index|Blood Glucose 8459 SHBG 32558920 Hum. Reprod. 2020 10.1093/humrep/deaa098 0 0 0 3194 Female|Humans|Animals|*Polycystic Ovary Syndrome|Anti-Mullerian Hormone|Anovulation|Follicular Fluid|*Proestrus|Ovarian Follicle|Luteinizing Hormone|Estrogens 8459 SHBG 32558890 Hum. Reprod. 2020 10.1093/humrep/deaa089 0 0 0 3194 Male|Humans|*Cross-Sectional Studies|*Sperm Count|*Electronic Nicotine Delivery Systems|*Sperm|Semen Analysis|Luteinizing Hormone|Sperm Motility|Follicle Stimulating Hormone|Testosterone|Inhibins 8459 SHBG 32558739 Menopause 2020 10.1097/GME.0000000000001579 0 0 0 3194 Female|Humans|Michigan|*Menopause|Sex Hormone-Binding Globulin|*Women's Health|Follicle Stimulating Hormone|Oestradiol|Testosterone|Gonadal Steroid Hormones|Premenopause|Longitudinal Studies|Cohort Studies|African Continental Ancestry Group|European Continental Ancestry Group|Ethnic Groups|Asian Continental Ancestry Group 8459 SHBG 32555690 PLoS ONE 2020 PMC7302712 10.1371/journal.pone.0234622 0 0 0 3194 Male|Humans|Animals|*Acrylamide|*Nutrition Surveys|glycidamide|Epoxy Compounds|*Gonadal Steroid Hormones|Hemoglobins|Environmental Exposure 8459 SHBG 32550818 Biochem Med (Zagreb) 2020 PMC7271758 10.11613/BM.2020.020710 0 0 0 3194 Child|Adolescent|Humans|*Reference Values|Canada|*Laboratory|Biomarkers|Diagnostic Tests, Routine 8459 SHOX 32647378 Eur. 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Genet. 2020 10.1136/jmedgenet-2020-106842 0 0 0 122 Short Stature Homeobox Protein|Osteochondrodysplasias|Dwarfism|Homeodomain Proteins|Growth Disorders|DNA Copy Number Variations|Gene Duplication|Pedigree|Clubfoot 412 SHOX 32504378 Endocrine 2020 10.1007/s12020-020-02362-w 0 0 0 122 Humans|Child|*Growth Plate|Genome-Wide Association Study|Growth Disorders|*Dwarfism|Short Stature Homeobox Protein|Human Growth Hormone|Insulin-Like Growth Factor I|Homeodomain Proteins|Chondrogenesis 412 SHOX 32423256 Genet Test Mol Biomarkers 2020 10.1089/gtmb.2019.0226 0 0 0 122 412 SHOX 32344414 Horm Res Paediatr 2020 10.1159/000507215 0 0 0 122 Humans|*Haploinsufficiency|*Genes, Homeobox|Short Stature Homeobox Protein|Madelung Deformity|Growth Disorders|Osteochondrodysplasias|Human Growth Hormone|Homeodomain Proteins|Genetic Testing|Gene Deletion|*Regulatory Sequences, Nucleic Acid|*Genes, cdc|Fetal Diseases|SHOX protein, human 412 SHOX 32296097 Sci Rep 2020 PMC7160148 10.1038/s41598-020-63516-4 0 0 0 122 Pregnancy|Cattle|Female|Animals|Horses|Genome-Wide Association Study|Sexual Maturation|Breeding|Reproduction|Fertility|Phenotype|Genotype|Body Weight|Models, Genetic|*Phenotypic Plasticity 412 SHOX 32295321 J Clin Res Pediatr Endocrinol 2020 10.4274/jcrpe.galenos.2020.2020.0001 0 0 0 122 412 SHOX 32032347 Med. 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Monit. 2020 PMC7020756 10.12659/MSM.921233 0 0 0 122 *Osteosarcoma|*Cell Proliferation|*Apoptosis|*Cell Cycle|Bone Neoplasms|Cell Line, Tumor|*Genes, cdc|Viability, Cell|Messenger RNA|Flow Cytometry 412 SHOX2 32647207 Sci Rep 2020 PMC7347847 10.1038/s41598-020-67743-7 0 0 0 519 *Multivariate Analysis|*Astrocytomas, Anaplastic|Gliomas|Glioblastoma|Isocitrate Dehydrogenase|Brain Neoplasms|Prognosis|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Algorithms|Cohort Studies 184 SHOX2 32613323 HNO 2020 10.1007/s00106-020-00902-4 0 0 0 519 *Squamous Cell Carcinoma of Head and Neck|*Prognosis|*Epigenomics|Head and Neck Neoplasms|Carcinoma, Squamous Cell|DNA Methylation|Biomarkers, Tumor|Homeodomain Proteins 184 SHOX2 32398354 Development 2020 PMC7240299 10.1242/dev.186239 0 0 0 519 Mice|Animals|*Osteogenesis|*Mice, Knockout|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteoblasts|Cell Differentiation|Chondrogenesis|Mesenchymal Stem Cells|Mesoderm|Transcription Factor|*Sternum|Gene Expression Regulation, Developmental|Ebf3 protein, mouse 184 SHOX2 32361006 J Mol Diagn 2020 10.1016/j.jmoldx.2020.04.205 0 0 0 519 Humans|*DNA Methylation|*Prospective Studies|Septins|Cell Free DNA|Biomarkers, Tumor|Homeodomain Proteins|Mesothelioma, Malignant|Lung Neoplasms|Mesothelioma|SHOX2 protein, human 184 SHOX2 32266538 J. 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Disord. 2020 10.1016/j.nmd.2020.05.005 0 0 0 1064 Male|Humans|Adult|*Amyotrophic Lateral Sclerosis|*Phenotype|*Mutations|Pedigree|Hereditary Sensory and Motor Neuropathy|Muscular Atrophy, Spinal|Receptors, sigma|Family Members 92 Sigmar1 32409627 Aging (Albany NY) 2020 PMC7288944 10.18632/aging.103166 0 0 0 1064 Pregnancy|Humans|Female|*Ovarian Reserve|sigma-1 receptor|*Endoplasmic Reticulum Stress|Anti-Mullerian Hormone|Granulosa Cells|Follicle Stimulating Hormone|*Receptors, sigma|Ovarian Follicle|Follicular Fluid|Receptors, FSH|Ovary|Dehydroepiandrosterone|*Ovarian Diseases|*Apoptosis 92 Sigmar1 32318621 Alzheimers Dement (N Y) 2020 PMC7167374 10.1002/trc2.12013 0 0 0 1064 Humans|*Alzheimer Disease|tetrahydro-N, N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride|*Precision Medicine|*Artificial Intelligence|*Furans|Cholinesterase Inhibitors|Cognition|Activities of Daily Living|Treatment Outcome|Biomarkers|Genomics 92 Sigmar1 32305020 Transl Oncol 2020 PMC7163079 10.1016/j.tranon.2020.100763 0 0 0 1064 Humans|*Uniparental Disomy|*Larynx Cancer|Genome-Wide Association Study|Polymorphism, Single Nucleotide|*Oral Cavity|*Oropharynx|MED27 protein, human|Mediator Complex 92 Sigmar1 32193362 Science 2020 10.1126/science.aay2494 4 0 0 1064 Animals|Mice|*Endoplasmic Reticulum-Associated Degradation|*Adipocytes, Brown|*Mitochondrial Dynamics|Endoplasmic Reticulum|Endoplasmic Reticulum Stress|Ubiquitin-Protein Ligases|Mitochondria|Mitochondrial Membranes|Proteins 92 SIM2 32566271 Autoimmune Dis 2020 PMC7285398 10.1155/2020/6876920 0 0 0 147 *Interferon|*Down Syndrome|*Neurodegenerative Diseases|Transcription, Genetic|*Antiviral Agents|Trisomy|Gene Expression Regulation|Interferon-gamma|Trans-Activators|STAT1 Transcription Factor|Base Sequence 122 SIM2 32348746 Structure 2020 10.1016/j.str.2020.04.002 0 0 0 147 Humans|*PIAS Proteins|*Ubiquitin|SUMO-1 Protein|Small Ubiquitin-Related Modifier Proteins|Sumoylation|Ubiquitin Ligase E3|Protein Binding|Amino Acid Sequence|Post-Translational Modifications|Phosphorylation|SIM2 protein, human|Basic Helix-Loop-Helix Transcription Factors 122 SIM2 32176739 PLoS Pathog. 2020 PMC7105294 10.1371/journal.ppat.1008447 0 0 0 147 *Herpesvirus 4, Human|Proteomics|EBV-encoded nuclear antigen 1|*Epstein-Barr Virus Nuclear Antigens|Epstein Barr Virus Infection|Virus Latency|Virus Replication|Protein Binding|Host-Pathogen Interactions|Episome|Cell Line, Tumor 122 SIM2 32124945 Int. 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Biol. 2020 10.1016/j.ydbio.2020.05.008 0 0 0 330 *Catalytic Domain|SMARCA4 protein, human|*Transcription Factors|*DNA Helicases|*Nuclear Proteins|*Cell Differentiation|Chromatin Assembly and Disassembly|*Nephron|Chromosomal Proteins, Non-Histone|Progenitor Cells|Protein Binding|Cell Proliferation 281 SIX2 32483460 Theranostics 2020 PMC7255026 10.7150/thno.45816 0 0 0 330 281 SIX2 32460030 Cell Rep 2020 PMC7304247 10.1016/j.celrep.2020.107687 0 0 0 330 Humans|Human Induced Pluripotent Stem Cells|Insulin-Secreting Cells|*Cell Differentiation|Embryonic Stem Cells|Pluripotent Stem Cells|Islets of Langerhans|Insulin Secretion|Human Embryonic Stem Cells|Insulin|Glucose|Endocrine Cells|Pancreas|Diabetes Mellitus|Signal Transduction|Cell Therapy|SIX2 protein, human|Nerve Tissue Proteins|Homeodomain Proteins 281 SIX2 32277572 Genesis 2020 PMC7363584 10.1002/dvg.23365 0 0 0 330 Mice|Animals|Neural Crest Cells|Frontonasal dysplasia|Craniofacial Abnormalities|Transcription Factors|Homeodomain Proteins|Mesoderm|Gene Expression Regulation, Developmental|Wnt1 Protein|Heterozygote|Face|Six2 protein, mouse 281 SIX2 32226308 Int. 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Cell 2020 10.1091/mbc.E19-10-0569 0 0 0 193 Humans|*Kinetochores|*Chromosome Segregation|*Phosphorylation|*Mitosis|Microtubules|Spindle Apparatus|Microtubule-Associated Proteins|CDC2 Protein Kinase|Aurora Kinase B|Chromosomal Proteins, Non-Histone|Cytoskeletal Proteins|Nuclear Proteins|NDC80 protein, human|Ska3 protein, human 37 SKA3 32180800 Front Genet 2020 PMC7059753 10.3389/fgene.2020.00153 0 0 0 193 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Prognosis|*Disease Progression|Gene Expression Profiling|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Computational Biology|Biomarkers, Tumor|Protein Interaction Maps|Transcriptome 37 SKA3 32068236 Biosci. Rep. 2020 PMC7048675 10.1042/BSR20194335 1 0 0 193 *Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Lung Adenocarcinoma|Lung Neoplasms|Signal Transduction|Adenocarcinoma|Kinetochore|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Cell Line, Tumor|Up-Regulation|ErbB Receptors 37 SKOR1 32572201 Eur. J. Hum. Genet. 2020 10.1038/s41431-020-0670-4 0 0 0 30 Humans|Animals|Mice|*Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|Transcription Factor|MAP Kinase Kinase 5|*Gene Expression Regulation|Genome-Wide Association Study|Nerve Tissue Proteins|Sleep Disorder 24 SLC16A12 32249133 Drug Metab. Pharmacokinet. 2020 10.1016/j.dmpk.2020.01.008 0 0 0 24 Animals|creatine transporter|SLC6A8 protein, human|*Plasma Membrane Neurotransmitter Transport Proteins|*Nerve Tissue Proteins|Creatine|Biological Transport|Monocarboxylic Acid Transporters|Mutation|Cell Membrane|Oocytes 24 SLC16A4 32559011 J Gene Med 2020 10.1002/jgm.3243 0 0 0 345 Animals|*Wasp Venoms|*Wasp|*Desensitization, Immunologic|Arthropod Venoms|Bee Venoms|Anaphylaxis|Allergens|Immunoglobulin E|*Immunologic Factors 271 SLC16A4 31964840 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC6995024 10.1073/pnas.1913841117 0 0 0 345 Humans|Carbon-13|*Carbon Isotopes|Monocarboxylic Acid Transporters|*Magnetic Resonance Imaging|Pyruvic Acid|Symporters|Cell Line, Tumor|Muscle Proteins|Lactic Acid 271 SLC16A9 32566650 Biomed Res Int 2020 PMC7273407 10.1155/2020/1204605 0 0 0 89 Bioinformatics|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Colorectal Cancer|Gene Expression Regulation, Neoplastic|Databases, Genetic|Prognosis|Protein Interaction Mapping|Biomarkers, Tumor|Transcriptome|Signal Transduction 30 SLC16A9 32090094 Biomed Res Int 2020 PMC7013288 10.1155/2020/4321419 0 0 0 89 *Whole Exome Sequencing|*Mutation, Missense|Pedigree|Exome|Hyperuricemia|Phenotype|Gout|Genetic Predisposition|Mutations|Monosodium Urate 30 SLC22A9 32150922 Int J Mol Sci 2020 PMC7084758 10.3390/ijms21051791 2 0 0 139 *Avena|*Systems Biology|Organic Cation Transport Proteins|Organic Anion Transporters|Biological Transport|Carnitine|Multigene Family|Signal Transduction|Uric Acid|*Systems Analysis 30 SLC22A9 31985003 Hum. 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Pathol. 2020 10.1136/jclinpath-2020-206647 0 0 0 20 X-linked sideroblastic anemia|Anemia, Sideroblastic|Genetic Diseases, X-Linked|5-Aminolevulinate Synthetase|Mutations|*Frameshift Mutation|Mitochondrial Membrane Transport Proteins 35 SLC4A11 32520610 Am. J. Physiol., Cell Physiol. 2020 10.1152/ajpcell.00128.2020 0 0 0 80 Humans|*Protons|Endothelial Cells|Corneal endothelial dystrophy type 2|Corneal Dystrophies, Hereditary|Anion Transport Proteins|Antiporters|Ion Transport|Biological Transport|Bicarbonates|Endothelium, Corneal|HEK293 Cells|Mutation|Hydrogen-Ion Concentration|Sodium|SLC4A11 protein, human 104 SLC4A11 32455435 Invest. Ophthalmol. Vis. Sci. 2020 10.1167/iovs.61.5.47 0 0 0 80 Humans|*Corneal Endothelium|*Endothelial Cells|Cells, Cultured|*Ion Channel|Cell Count|Cell Differentiation|*Cell Line|Flow Cytometry|Tissue Donors|Microscopy, Phase-Contrast 104 SLC4A11 32328985 Ann. Surg. Oncol. 2020 10.1245/s10434-020-08498-3 0 0 0 80 *Colon Cancer|Prognosis|Neoplasm Staging|Kaplan-Meier Estimate|Neoplasm Recurrence, Local|DNA Microarray 104 SLC4A11 32031579 Invest. Ophthalmol. Vis. Sci. 2020 PMC7324437 10.1167/iovs.61.2.7 0 0 0 80 Rabbits|Mice|Animals|*Lactic Acid|*Corneal Endothelium|Ouabain|*Biological Transport|Biological Transport, Active|Corneal Stroma|Sodium-Potassium-Exchanging ATPase|*Biochemical Phenomena 104 SLFN11 32586373 Clin Epigenetics 2020 PMC7318526 10.1186/s13148-020-00876-8 0 0 0 116 Humans|*Small Cell Lung Carcinoma|*DNA Methylation|*B-DNA|*Epigenome|Lung Neoplasms|Antitumor Agents|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Cell Lineage|Gene Expression|Apoptosis 72 SLFN11 32474729 Virchows Arch. 2020 10.1007/s00428-020-02840-6 0 0 0 116 Humans|*RNA-Seq|DNA Damage|*DNA|Drug Resistance, Neoplasm|Cell Line, Tumor|Cisplatin|Gene Expression Regulation, Neoplastic|Nuclear Proteins|Carboplatin|*Whole Exome Sequencing|Topoisomerase Inhibitors|SLFN11 protein, human 72 SLFN11 32444417 Clin. Cancer Res. 2020 10.1158/1078-0432.CCR-19-4121 0 0 0 116 Humans|Female|olaparib|*Poly(ADP-ribose) Polymerase Inhibitors|cediranib|*Phthalazines|*Carcinoma, Ovarian Epithelial|*Piperazines|*Quinazolines|*Ovarian Cancer|BRCA2 Protein|BRCA1 Protein|Antineoplastic Combined Chemotherapy Protocols|Germ-Line Mutation|Neoplasm Recurrence, Local|Drug Administration Schedule 72 SLFN11 32321568 Epigenetics Chromatin 2020 PMC7175505 10.1186/s13072-020-00343-x 1 0 0 116 *Sequencing, Next-Generation|Chromatin Immunoprecipitation|Sequence Analysis, DNA|Bioinformatics|Software|Genomics|Chromatin|Genome 72 SLFN11 32292519 Theranostics 2020 PMC7150495 10.7150/thno.42869 0 0 0 116 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|MTOR protein, human|*TOR Serine-Threonine Kinases|*Tumorigenesis|*Cell Transformation, Neoplastic|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Cell Movement|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|Cell Proliferation|Disease Progression|SLFN11 protein, human|Nuclear Proteins 72 SLFN11 32279088 J. Cancer Res. Clin. Oncol. 2020 PMC7256072 10.1007/s00432-020-03211-z 0 0 0 116 olaparib|*Temozolomide|*Desmoplastic Small Round Cell Tumor|*Phthalazines|*Piperazines|Poly(ADP-ribose) Polymerase Inhibitors|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Antineoplastic Agents|Cell Line, Tumor|Xenograft Model Antitumor Assays|Drug Resistance, Neoplasm|Apoptosis|Drug Synergism|Cell Proliferation 72 SLFN11 32209474 Cell Rep 2020 PMC7240837 10.1016/j.celrep.2020.02.117 0 0 0 116 *Genes, Immediate-Early|*Chromatin Assembly and Disassembly|Camptothecine|Ataxia Telangiectasia Mutated Proteins|Topoisomerase I Inhibitors|Nuclear Proteins|DNA Damage|Cell Line, Tumor|Drug Resistance, Neoplasm|Chromatin|Genes, cdc|prexasertib|Pyrazines|Cell Cycle Arrest|Pyrazoles 72 SLFN11 32127465 Mol. Cancer Ther. 2020 10.1158/1535-7163.MCT-19-0926 0 0 0 116 Humans|Male|*Platinum|Prostatic Neoplasms, Castration-Resistant|Androstenes|Prostate-Specific Antigen|Neoplastic Cells, Circulating|Biomarkers, Tumor|Kaplan-Meier Estimate|Treatment Outcome|SLFN11 protein, human|Nuclear Proteins 72 SLFN11 32107283 Mol. Cell Proteomics 2020 PMC7124473 10.1074/mcp.RA120.001954 0 0 0 116 Humans|*Proteomics|*Genetic Profile|Neoplasm Recurrence, Local|*Anal Cancer|*Carcinoma, Squamous Cell|Biomarkers, Tumor|Anal Canal 72 SLFN11 32075943 Sci Transl Med 2020 10.1126/scitranslmed.aax2625 1 0 0 116 Humans|*Topoisomerase I Inhibitors|*Triple-Negative Breast Cancers|TOP1 protein, human|Topoisomerase I|Irinotecan|CHEK1 protein, human|Checkpoint Kinase 1|Camptothecin|DNA Repair|Poly(ADP-ribose) Polymerase Inhibitors|Ataxia Telangiectasia Mutated Proteins|NSC 724998|Isoquinolines|DNA Damage|Homologous Recombination|Cell Line, Tumor|Benzodioxoles|Topoisomerase II Inhibitors 72 SLFN11 32053203 J. Antimicrob. Chemother. 2020 10.1093/jac/dkaa003 0 0 0 116 Humans|*HIV-1|Anti-Retroviral Agents|Viral Load|HIV Infections|Proviruses|CD4-Positive T-Lymphocytes|*HIV Seropositivity|*Biomarkers|Leukocytes, Mononuclear 72 SLFN11 32004714 J Thorac Oncol 2020 10.1016/j.jtho.2020.01.012 0 0 0 116 *Poly(ADP-ribose) Polymerase Inhibitors|*Temozolomide|O-(6)-methylguanine|Mesothelioma, Malignant|*Mesothelioma|*O(6)-Methylguanine-DNA Methyltransferase|BRCA1 protein, human|*BRCA1 Protein|Guanine|*Lung Neoplasms|Phthalazines|Dacarbazine|Poly(ADP-ribose) Polymerases|Cell Line, Tumor|DNA Repair|Synthetic Lethality|Piperazines 72 SLFN12 32613204 Nat Cancer 2020 PMC7328899 10.1038/s43018-019-0018-6 1 0 0 86 Humans|Cell Line, Tumor|Antineoplastic Agents|Repurposing, Drug|Drug Resistance, Neoplasm|Drug Resistance, Multiple|Disulfiram|ABCB1 Protein 24 SLFN12 32591543 Nat Commun 2020 PMC7319972 10.1038/s41467-020-17052-4 0 0 0 86 *Cyclic Nucleotide Phosphodiesterases, Type 3|*Apoptosis|Antineoplastic Agents|Cancer|*Alkaloids 24 SLFN12 32005668 J. 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Urol. 2020 10.1016/j.eururo.2020.06.029 0 0 0 185 Female|Humans|*Vesicovaginal Fistula|*Robotic Surgical Procedures|*Urology|*Consensus|*Robotics|*Reconstructive Surgical Procedures|Laparoscopy|Operative Time|*Histological Techniques 609 SLK 32652700 Clin Transplant 2020 10.1111/ctr.14036 0 0 0 185 Adult|Humans|*Kidney Transplantation|*Immunosuppression|Graft Survival|Graft Rejection|Immunosuppressive Agents|*Steroids|*Liver Transplantation|Tacrolimus|*Kidney|Transplant Recipients|*Immune Tolerance|*Liver 609 SLK 32631337 Cardiovasc Diabetol 2020 PMC7339487 10.1186/s12933-020-01078-5 0 0 0 185 Humans|*Metformin|*Diabetes Mellitus, Type 2|*Cardiovascular Diseases|*Risk Factors|Hypoglycemic Agents|Dipeptidyl-Peptidase IV Inhibitors|Sodium-Glucose Transporter 2 Inhibitors|Incretins|Glucagon-Like Peptide 1|*Cardiovascular System|Blood Glucose|SLC5A2 protein, human|Sodium-Glucose Transporter 2 609 SLK 32620520 Dig Liver Dis 2020 10.1016/j.dld.2020.05.051 0 0 0 185 Humans|*Liver Neoplasms|Chemoembolization, Therapeutic|Camptothecin|Irinotecan|Colorectal Neoplasms|Antineoplastic Agents, Phytogenic|Microspheres|Treatment Outcome 609 SLK 32607806 Arch. 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Biol. 2020 10.1007/s11103-020-01004-z 0 0 0 164 Female|Male|*Oryza|Gene Expression Regulation, Plant|Gametogenesis, Plant|Pollen|Ovule|Plant Proteins|Genes, Plant|Seed|Meiosis|Plants, Genetically Modified|Chromosomes, Plant|*Reproduction|Gene Expression Profiling|Phenotype|Gene Expression Regulation, Developmental 138 Smarcal1 32117046 Front Endocrinol (Lausanne) 2020 PMC7010808 10.3389/fendo.2019.00934 0 0 0 164 Humans|Mice|Animals|Phenotypes|*Disease Models, Animal|Ethylnitrosourea|Mutations|Mice, Transgenic|Mutagenesis|Osteochondrodysplasias|Cilia|X-Linked Gene|Gene Expression|Proteins|Knockouts, Gene|Human Genetics 138 Smarcal1 32115305 Brain Dev. 2020 10.1016/j.braindev.2020.01.008 0 0 0 164 Humans|Spondyloepiphyseal dysplasia, congenita|Schimke immunoosseous dysplasia|*Osteochondrodysplasias|*Arteriosclerosis|*Nephrotic Syndrome|*Primary Immunodeficiency Diseases|*Pulmonary Embolism|Thymic aplasia|Immunologic Deficiency Syndromes|Kidney Diseases|DNA Helicases|*Electroencephalography|Microcephaly|Headaches|Cerebrovascular Disorders|Migraine|Thymus Gland|SMARCAL1 protein, human 138 Smarcal1 31974116 J. 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Rep. 2020 PMC7041105 10.3892/or.2020.7473 0 0 0 3567 Humans|Female|*Curcumin|*Synuclein|BRCA1 protein, human|*BRCA1 Protein|*DNA Methylation|*Promoter Regions, Genetic|Genes, BRCA1|Gene Expression Regulation, Neoplastic|Triple Negative Breast Neoplasms|Ovarian Cancer|Cell Line, Tumor|MCF-7 Cells|Disease-Free Survival|TET1 protein, human|Mixed Function Oxygenases|Proto-Oncogene Proteins 169 SNX10 32428616 Can J Cardiol 2020 10.1016/j.cjca.2020.05.010 0 0 0 57 Mice|Animals|*Foam Cells|*Atherosclerosis|*CD36 Antigens|Apolipoproteins E|Plaque, Atherosclerotic|Monocyte-Derived Macrophages|Lipoproteins, LDL|Mice, Knockout|Monocytes|Mice, Inbred C57BL|Cytokines|Disease Models, Animal|*Protective Agents|SNX10 protein, mouse|Sorting Nexins 51 SNX10 32398790 Leukemia 2020 10.1038/s41375-020-0856-3 0 0 0 57 CCCTC-Binding Factor|Chromatin|Homeodomain Proteins|Histone H3|Chromosomal Proteins, Non-Histone|Repressor Proteins|Gene Expression Regulation|Binding Sites|Cell Cycle Proteins|Cell Line|Protein Binding|Leukemia, Myeloid, Acute 51 SNX10 32316875 Circ. 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Cell. Biochem. 2020 10.1002/jcb.29674 0 0 0 81 Humans|*RNA, Long Noncoding|*Triple-Negative Breast Cancer|*Disease Progression|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Upregulation|Cell Movement|Apoptosis|ORMDL3 protein, human|Membrane Proteins 77 SOX21 32243783 Dev. Cell 2020 10.1016/j.devcel.2020.03.002 0 0 0 81 Humans|Mice|Animals|*Peroxisomes|Colitis|*Intestines|Intestinal Epithelium|Inflammatory Bowel Disease|Dextran Sulfate|*Cell Differentiation|Janus Kinases|Colon|Epithelial Cells|Signal Transduction|Wound Healing 77 SOX21 32124921 Biosci. 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Dev. 2020 10.1016/j.mod.2020.103616 0 0 0 109 Female|Pregnancy|Mice|Animals|*Tumor Suppressor Protein p53|*Organogenesis|Kidney|Ureter|Wnt Proteins|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2|Proto-Oncogene Proteins c-ret|Morphogenesis|Gene Expression Regulation, Developmental|Signal Transduction|Apoptosis|Embryogenesis 165 SOX8 32460025 Cell Rep 2020 10.1016/j.celrep.2020.107683 0 0 0 109 Animals|*Drosophila|*Intestines|Drosophila Proteins|Cell Differentiation|Janus Kinases|Signal Transduction|*Homeostasis|Stem Cells|SOX9 protein, human|*SOX9 Transcription Factor|Stem Cell Self-Renewal|Cell Proliferation|Intestinal Mucosa|Enterocytes|ErbB Receptors|*Mammals|Regeneration|Sox100B protein, Drosophila 165 SOX8 32450947 Elife 2020 PMC7250573 10.7554/eLife.53972 0 0 0 109 Male|Female|Animals|Testis|Sex Determination Processes|Sex Differentiation|Ovary|Gonads|SOX9 Transcription Factor|Wnt4 Protein|Sertoli Cells|Cell Differentiation|Thrombospondins|beta Catenin|Gene Expression Regulation, Developmental|Signal Transduction 165 SOX8 32411596 Front Oncol 2020 PMC7198745 10.3389/fonc.2020.00557 0 0 0 109 Pregnancy|Female|Humans|Cell Line, Tumor|*Proteomics|*Gestational Trophoblastic Neoplasia|Drug Resistance, Neoplasm|Neoplasm Recurrence, Local|Upregulation 165 SOX8 32369742 Dev. Cell 2020 PMC7255058 10.1016/j.devcel.2020.04.005 0 0 0 109 *Neural Crest|Heart|*Congenital Heart Defects|Persistent Truncus Arteriosus|Heart Ventricles|Cell Movement|Organogenesis|Hindbrain 165 SOX8 32307911 Cancer Med 2020 PMC7300415 10.1002/cam4.3041 1 0 0 109 Humans|*Tongue Neoplasms|*Squamous Cell Carcinoma of Head and Neck|*Signal Transduction|Prognosis|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Epithelial-Mesenchymal Transition|Cell Movement|Upregulation|Cell Proliferation|Biomarkers, Tumor|Kaplan-Meier Analysis|Head and Neck Neoplasms|GOLPH3 protein, human|Membrane Proteins 165 SOX8 32099981 Sheng Li Xue Bao 2020 0 0 0 109 Male|Female|Mice|Animals|*Gonads|Sex Determination Processes|Testis|Sex Differentiation|Sex-Determining Region Y Protein|Ovary|*Cell Differentiation|CTNNB1 protein, human|beta Catenin|Wnt4 Protein|Germ Cells|SOX9 Transcription Factor|Forkhead Box Protein L2|Gene Expression Regulation, Developmental|FGFR2 protein, human|Receptor, Fibroblast Growth Factor, Type 2|SOXE Transcription Factors|Embryonic Development 165 SOX8 32048324 Andrologia 2020 10.1111/and.13531 0 0 0 109 Humans|Male|Mice|Animals|Azoospermia, Nonobstructive|*Azoospermia|*Oligospermia|Infertility, Male|Single Nucleotide Polymorphisms|Frequencies, Allele|Genetic Predisposition to Disease|Genotype|*Ethnic Groups|Sertoli Cells|Blood-Testis Barrier|Case-Control Study|Sox8 protein, mouse|SOXE Transcription Factors 165 SOX8 31923463 Comp. 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Sci. 2020 10.1098/rstb.2019.0540 0 0 0 198 Mice|Animals|Reproductive Isolation|Hybridization, Genetic|*DNA Copy Number Variations|Mating Preference, Animal|Genetics, Population|Selection, Genetic|Phenotype|*Reinforcement, Psychology 84 sp110 32642571 Heliyon 2020 PMC7334237 10.1016/j.heliyon.2020.e04254 0 0 0 198 Cattle|Animals|*Polymorphism, Single Nucleotide|Paratuberculosis|Mycobacterium avium subsp. paratuberculosis|Cattle Diseases|Enzyme-Linked Immunosorbent Assay 84 sp110 32395362 Case Rep Pediatr 2020 PMC7199573 10.1155/2020/3460631 0 0 0 198 Humans|Hepatic venoocclusive disease with immunodeficiency|*Hepatic Veno-Occlusive Disease|*Immunologic Deficiency Syndromes|*Mutation|Minor Histocompatibility Antigens|Nuclear Proteins|Sp110 protein, human 84 sp110 32386862 Trends Immunol. 2020 10.1016/j.it.2020.04.007 0 0 0 198 Humans|*Chromatin|SP140 protein, human|Antigens, Nuclear|Transcription Factors|Nuclear Proteins|Autoantigens|Protein Domains|Protein Binding|Amino Acid Sequence|Mutations|Sp110 protein, human|Minor Histocompatibility Antigens 84 sp110 32063569 J Affect Disord 2020 10.1016/j.jad.2020.01.161 0 0 0 198 *Genome-Wide Association Study|*Obsessive Compulsive Disorder|Multifactorial Inheritance|Severity of Illness Index 84 sp110 32042028 Sci Rep 2020 PMC7010774 10.1038/s41598-020-59186-x 0 0 0 198 Female|Humans|*MicroRNAs|*FSH Receptor|CYP19A1 protein, human|*Aromatase|*Granulosa Cells|Gene Expression Profiling|Bioinformatic|Granulosa Cell, Cumulus|Gene Expression Regulation|Signal Transduction|FMNL3 protein, human|Formins|Sp110 protein, human|Nuclear Proteins|Minor Histocompatibility Antigens 84 SP6 32629685 Medicine (Baltimore) 2020 PMC7337562 10.1097/MD.0000000000020909 0 0 0 277 Humans|Female|Child|Adult|*Hashimoto Disease|*Acupuncture Therapy|Acupuncture Points|*Research Design|Treatment Outcome|Outcome Assessment, Health Care|Time Factors|*Health Services|*Fertility 1251 SP6 32567332 Acupunct Med 2020 10.1177/0964528420926173 0 0 0 277 *Acupuncture Points|*Acupuncture Treatments|*Pain|Pain Management|*Data Mining|Treatment Protocols 1251 SP6 32532168 Int. 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Neurosci. 2020 10.1080/00207454.2020.1782903 0 0 0 277 1251 SP6 32517477 Acupunct Med 2020 10.1177/0964528420920280 0 0 0 277 *Menopause|Hot Flashes|*Treatment, Acupuncture|Quality of Life 1251 SP6 32507430 Complement Ther Med 2020 10.1016/j.ctim.2020.102413 0 0 0 277 Pregnancy|Female|Humans|*Labor Pain|*Acupressure|Labor, Obstetric|Acupuncture Points|Pain Measurement|*Fetal Development|Ear 1251 SP6 32497714 J Acupunct Meridian Stud 2020 10.1016/j.jams.2020.05.002 0 0 0 277 Humans|*Acupressure|*Renal Dialysis|*Pruritus|Kidney Failure, Chronic|Acupuncture Points|*Laboratory 1251 SP6 32489015 Am J Med Genet C Semin Med Genet 2020 10.1002/ajmg.c.31799 0 0 0 277 Humans|Male|Female|Triple X syndrome|*Turner Syndrome|*Transcriptome|Sex Chromosome Aberrations|Sex Chromosome Disorders of Sex Development|Trisomy|X Chromosome Inactivation|Chromosomes, Human, X|X-Chromosome Genes|DNA Methylation|*Epigenetic|Gene Dosage|AMOT protein, human|Membrane Proteins|Intercellular Signaling Peptides and Proteins 1251 SP6 32447848 Zhen Ci Yan Jiu 2020 10.13702/j.1000-0607.190285 0 0 0 277 Rats|Animals|*Electroacupuncture|*Irritable Bowel Syndrome|Acupuncture Points|*Defecation|*Intestines|Diarrhea|*Intestinal Mucosa 1251 SP6 32430690 Dev. 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Total Environ. 2020 10.1016/j.scitotenv.2020.139233 0 0 0 28 Humans|Male|Mice|Animals|*Acrosome|*Sperm Motility|*Arsenic|*Sperm|*Spermiogenesis|Sperm Flagellum|Infertility, Male|Testes|*Flagellum|Fertility|*Proteomics|A Kinase Anchor Proteins|*Protein Processing, Post-Translational 28 SPAG16 31901658 Chemosphere 2020 10.1016/j.chemosphere.2019.125772 0 0 0 28 Humans|Male|Mice|Animals|*Sperm Tail|*Testis|*Fluorides|Sperm Motility|Sperm|Spermatogenesis|Infertility, Male|AKAP4 protein, human|A Kinase Anchor Proteins|Axoneme|*Proteomics|mRNA|Mutation|DNAH1 protein, human|Dyneins|SPAG6 protein, mouse|Microtubule Proteins|SPEF2 protein, mouse 28 SPAG6 32537026 Oncol Lett 2020 PMC7291649 10.3892/ol.2020.11607 0 0 0 61 59 SPAG6 32346337 Saudi J Biol Sci 2020 PMC7182980 10.1016/j.sjbs.2020.03.017 0 0 0 61 59 SPAG6 32216237 Zhonghua Nan Ke Xue 2020 0 0 0 61 59 SPAG6 32124190 J. Assist. Reprod. Genet. 2020 PMC7183039 10.1007/s10815-020-01721-w 0 0 0 61 Pregnancy|Male|Humans|Female|*Sperm Injections, Intracytoplasmic|*Pregnancy Outcome|Infertility, Male|Sperm Tail|Pregnancy Rate|Spermatozoa|*Mutations|SPAG6 protein, human|Microtubule Proteins 59 SPAG6 31965676 Mol. Reprod. Dev. 2020 PMC7187922 10.1002/mrd.23318 0 0 0 61 Microtubule Proteins|Vesicular Transport Proteins|Amino Acid Sequence 59 SPAG6 31901658 Chemosphere 2020 10.1016/j.chemosphere.2019.125772 0 0 0 61 Humans|Male|Mice|Animals|*Sperm Tail|*Testis|*Fluorides|Sperm Motility|Sperm|Spermatogenesis|Infertility, Male|AKAP4 protein, human|A Kinase Anchor Proteins|Axoneme|*Proteomics|mRNA|Mutation|DNAH1 protein, human|Dyneins|SPAG6 protein, mouse|Microtubule Proteins|SPEF2 protein, mouse 59 SPATA16 32582379 Mol Cytogenet 2020 PMC7310204 10.1186/s13039-020-00495-1 0 0 0 7 Humans|Male|Acrosome|Infertility, Male|Sperm Head|Globozoospermia|Spermatozoa|Homozygote|Gene Deletion|Point Mutation|Membrane Proteins 33 SPATA16 32054438 BMC Evol. Biol. 2020 PMC7020506 10.1186/s12862-019-1575-0 0 0 0 7 Male|Animals|Humans|*Adaptation, Physiological|*Reproduction|Selection, Genetic|Phylogeny|Evolution, Molecular|Testis|Spermatogenesis|*Acclimatization|Primate|Hominidae|Databases, Genetic 33 SPATA16 31985809 Hum. Reprod. 2020 PMC6993856 10.1093/humrep/dez246 0 0 0 7 Male|Humans|*Teratozoospermia|*Exome|*Whole Exome Sequencing|Infertility, Male|Spermatozoa|Point Mutation|Alleles|Gene Deletion|Membrane Proteins 33 SPDEF 32637364 Front Cell Infect Microbiol 2020 PMC7318795 10.3389/fcimb.2020.00278 0 0 0 740 Humans|*Rhinovirus|*Tiotropium Bromide|*Fluticasone|Mucin 5AC|Epithelial Cell|Respiratory Mucosa|MUC1 protein, human|*Mucin-1|Goblet Cells|Interleukin-13|Bronchi|Asthma|Cells, Cultured|Cell Differentiation|Mucus|Chronic Obstructive Pulmonary Disease|Adrenal Cortex Hormones|Signal Transduction 188 SPDEF 32547225 Cancer Manag Res 2020 PMC7259446 10.2147/CMAR.S243748 0 0 0 740 Humans|Male|Proto-Oncogene Proteins c-ets|Oncogenes|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Prostatic Neoplasms 188 SPDEF 32545919 Int J Mol Sci 2020 PMC7352441 10.3390/ijms21124243 0 0 0 740 Humans|Male|*Transcription Factors|*Prostatic Neoplasms|*Biomarkers|Castration|SPDEF protein, human|Proto-Oncogene Proteins c-ets|Zbtb46 protein, human 188 SPDEF 32490214 Biochem Biophys Rep 2020 PMC7261704 10.1016/j.bbrep.2020.100768 0 0 0 740 *Epithelial-Mesenchymal Transition|*Up-Regulation|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Signal Pathway|Proto-Oncogene Proteins c-ets|Cell Line, Tumor|Cell Movement|Lung Cancer|Transcription Factors 188 SPDEF 32432922 Am. J. Physiol. Lung Cell Mol. Physiol. 2020 10.1152/ajplung.00023.2020 0 0 0 740 Humans|*Gene Regulatory Networks|Epithelial-Mesenchymal Transition|*Hepatocyte Nuclear Factor 3-alpha|*Cells, Epithelial|Hepatocyte Nuclear Factor 3-beta|Epithelium|Chromatin Immunoprecipitation|Genome|Morphogenesis|*Respiratory System|FOXA1 protein, human 188 SPDEF 32275839 Am. J. Respir. Cell Mol. Biol. 2020 10.1165/rcmb.2019-0454OC 0 0 0 740 Humans|*Particulate Matter|*Nasal Epithelium|Air Pollution|*Epithelium|Air Pollutants|Mucin 5AC|Respiratory Mucosa|Mucus|Asthma|Lung 188 SPDEF 32223448 Epigenomics 2020 10.2217/epi-2020-0060 0 0 0 740 188 SPDEF 32091413 J. Clin. Invest. 2020 PMC7108892 10.1172/JCI131041 0 0 0 740 Humans|Male|*Circulating Tumor DNA|Prostatic Neoplasms, Castration-Resistant|Receptors, Androgen|DNA Methylation|Epigenesis, Genetic|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|DNA Copy Number Variations|Adenocarcinoma|Epigenomic|Sequencing, Whole Exome|Orchiectomy|INSM1 protein, human|Repressor Proteins|ASXL3 protein, human|Transcription Factors 188 SPDEF 32034274 Mucosal Immunol 2020 10.1038/s41385-020-0262-1 1 0 0 740 Mice|Animals|*Exenatide|*Peroxisome Proliferator-Activated Receptors|*Mucus|Pulmonary Disease, Chronic Obstructive, Severe Early-Onset|Chronic Obstructive Pulmonary Disease|Goblet Cell|*Signal Transduction|STAT6 protein, human|STAT6 Transcription Factor|Pyocyanin|Mucin 5AC|IL 13|Hepatocyte Nuclear Factor 3-beta|*Phosphoric Monoester Hydrolases|Cystic Fibrosis|Metaplasia|*Homeostasis|Glp1r protein, mouse 188 SPDEF 31953222 Ocul Surf 2020 PMC7125021 10.1016/j.jtos.2019.12.006 0 0 0 740 Mice|Animals|*Goblet Cell|*Conjunctiva|Tear|Dry Eye Syndromes|Mice, Knockout|IL 12|Mucins|Interferon-gamma|Tissue, Mucosal|Gene Expression Regulation|Proto-Oncogene Proteins c-ets|Retinoic Acid|Signal Transduction|Cell Communication 188 SPEF2 32246154 Hum. Mol. Genet. 2020 10.1093/hmg/ddaa057 0 0 0 21 Humans|Aged|*Whole Exome Sequencing|Genome-Wide Association Study|*Exome|*Age Related Macular Degeneration|Complement Factor I|Complement Factor H|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Case-Control Studies|TACC2 protein, human|Carrier Proteins|Tumor Suppressor Proteins 34 SPEF2 32126384 Theriogenology 2020 10.1016/j.theriogenology.2020.02.029 0 0 0 21 Male|Humans|Arrest of spermatogenesis|Spermatogenesis|*Azoospermia|Testes|Infertility, Male|Spermatocytes|Spermatogonia|Meiosis|Breeding|Hybridization, Genetic 34 SPEF2 31942643 Hum. Genet. 2020 10.1007/s00439-020-02110-0 0 0 0 21 Humans|Male|Mice|Female|Animals|*Cilia|*Sperm Flagellum|*Primary Ciliary Dyskinesia|*Flagella|Axoneme|Infertility, Male|*Phenotypes|Spermatozoa|Sequencing, Whole Exome|Homozygote|*Multiple Abnormalities|Mutations|SPEF2 protein, mouse|Proteins 34 SPEF2 31901658 Chemosphere 2020 10.1016/j.chemosphere.2019.125772 0 0 0 21 Humans|Male|Mice|Animals|*Sperm Tail|*Testis|*Fluorides|Sperm Motility|Sperm|Spermatogenesis|Infertility, Male|AKAP4 protein, human|A Kinase Anchor Proteins|Axoneme|*Proteomics|mRNA|Mutation|DNAH1 protein, human|Dyneins|SPAG6 protein, mouse|Microtubule Proteins|SPEF2 protein, mouse 34 spic 32611235 Circ. 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J. Physiol. Lung Cell Mol. Physiol. 2020 10.1152/ajplung.00191.2019 0 0 0 42 Animals|Humans|Infant, Newborn|Bronchopulmonary Dysplasia|Hyperoxia|Lung|Animals, Newborn 35 srpx 32311840 Cancer Med 2020 PMC7300398 10.1002/cam4.3047 1 0 0 33 *Carcinoma, Hepatocellular|*Transcriptome|*Liver Neoplasms|*Cancer Stem Cell|*Liver|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|SFRP1 protein, human|Membrane Proteins 50 srpx 31910243 PLoS ONE 2020 PMC6946124 10.1371/journal.pone.0227154 0 0 0 33 Cattle|Animals|*Weight Gain|Animal Feed|Animal Nutritional Physiological Phenomena|Transcriptome|*Adipose Tissue|Breeding|Red Meat|Diet|Eating|Gene Expression Profiling|Phenotypes|Lipid Metabolism|Liver|Signal Transduction 50 srpx2 32661396 Nat. Neurosci. 2020 10.1038/s41593-020-0672-0 0 0 0 105 Synapses|*Neurons|*Complement|SRPUL protein, human|*Membrane Proteins|*Inhibitors, Complement|*Neoplasm Proteins|Nerve Tissue Proteins|Microglia|Complement C1q|Cerebral Cortex 75 srpx2 32550700 Acta Biochim. Pol. 2020 10.18388/abp.2020_5158 0 0 0 105 75 srpx2 32509446 PeerJ 2020 PMC7245335 10.7717/peerj.9038 0 0 0 105 Humans|*Glioma|Brain Neoplasms|Prognosis|Gene Expression Profiling|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Macrophage|Transcriptome|Computational Biology|*Neovascularization, Pathologic|Algorithms 75 srpx2 32455867 Int J Mol Sci 2020 PMC7279144 10.3390/ijms21103655 0 0 0 105 Male|*Carcinoma, Squamous Cell|emerin|*Mouth Neoplasms|*Tumor Promoters|*Membrane Proteins|*Nuclear Proteins|Nerve Tissue Proteins|Cell Line, Tumor|Cell Movement|Neovascularization, Pathologic|*Cell Transformation, Neoplastic|Disease Progression 75 srpx2 32161469 Onco Targets Ther 2020 PMC7049857 10.2147/OTT.S225602 1 0 0 105 *Osteosarcoma|*Cell Proliferation|SRPUL protein, human|*Neoplasm Proteins|*Signal Transduction|Bone Neoplasms|Neoplasm Invasiveness|Cell Movement|*Membrane Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Gene Knockdown Techniques|Nerve Tissue Proteins|Transcription Factors|*Neoplastic Processes 75 STC1 32600423 World J Surg Oncol 2020 PMC7325073 10.1186/s12957-020-01921-9 0 0 0 734 Humans|*Prognosis|*Colonic Neoplasms|*Adenocarcinoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|MicroRNAs|Kaplan-Meier Estimate|Gene Expression Profiling|Tumor Microenvironment|Transcription Factors|Colon 254 STC1 32579928 Cell Rep 2020 PMC7326292 10.1016/j.celrep.2020.107802 0 0 0 734 Humans|Female|*Lung Adenocarcinoma|*Adenocarcinoma|teleocalcin|*Glycoproteins|*Fibroblast|*Macrophages|Tumor Microenvironment|*Uterine Cervical Neoplasms|Lung Neoplasms 254 STC1 32528873 Front Oncol 2020 PMC7258082 10.3389/fonc.2020.00669 0 0 0 734 *Temozolomide|*Glioblastoma|Dacarbazine|DNA Modification Methylases|Antineoplastic Agents, Alkylating|Glioma|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Prognosis|Tumor Suppressor Proteins|Cell Line, Tumor|Kaplan-Meier Estimate|Drug Resistance, Neoplasm|DNA Methylation|*Gene Expression 254 STC1 32499821 Front Genet 2020 PMC7243251 10.3389/fgene.2020.00503 0 0 0 734 Female|Animals|*mRNA|*Transcriptome|*RNAs, Circular|*Chickens|*Transcriptome Analysis|Theca Cells|Granulosa Cells|Ovarian Follicle|Gene Regulatory Networks|Bioinformatic|MicroRNAs|Cell Differentiation 254 STC1 32468698 J. Cell. Mol. Med. 2020 PMC7348177 10.1111/jcmm.15348 1 0 0 734 Humans|Animals|teleocalcin|*Glycoprotein|Cell Line, Tumor|Endocrine System 254 STC1 32431516 Onco Targets Ther 2020 PMC7200234 10.2147/OTT.S242300 0 0 0 734 Humans|Female|*RNA, Long Noncoding|*Lung Neoplasms|*Lung Adenocarcinoma|MicroRNAs|Carcinoma, Non-Small-Cell Lung|*Adenocarcinoma|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|*Uterine Cervical Neoplasms|*Neoplastic Processes|Up-Regulation|Apoptosis|*Colon Cancer|Signal Transduction|Disease Progression 254 STC1 32379914 Stem Cells 2020 10.1002/stem.3198 0 0 0 734 Humans|ZYX protein, human|*Zyxin|teleocalcin|*Actins|*Mesenchymal Stem Cells|Mechanotransduction, Cellular|*Glycoproteins|Fibers, Stress|*Myosin|Focal Adhesions|Cell Adhesion|Epithelial Cells|Fibroblasts|Apoptosis|Uncoupling Protein 2 254 STC1 32379497 Cancer Biother. Radiopharm. 2020 10.1089/cbr.2019.3344 0 0 0 734 254 STC1 32364536 J. Clin. Invest. 2020 PMC7260026 10.1172/JCI133187 0 0 0 734 Humans|teleocalcin|*Hematopoiesis|Hematopoietic Stem Cells|*Leukemia, Myeloid, Acute|*Glycoproteins|Bone Marrow|Mesenchymal Stromal Cells|Stem Cell Niche|Cell Differentiation|Bone Marrow Cells|Coculture Techniques|Tumor Microenvironment|Cell Proliferation 254 STC1 32318235 Oxid Med Cell Longev 2020 PMC7153002 10.1155/2020/1898213 0 0 0 734 Humans|Rats|Animals|NFE2L2 protein, human|*NF-E2-Related Factor 2|teleocalcin|*Acute Kidney Injury|*Mitochondria|*Glycoprotein|Oxidative Stress|*GA-Binding Protein Transcription Factor|Signal Transduction|Contrast Media|Apoptosis 254 STC1 32296395 Front Endocrinol (Lausanne) 2020 PMC7136389 10.3389/fendo.2020.00172 0 0 0 734 Animals|teleocalcin|Glycoproteins|*Peptide Hormones|Amino Acid Sequence|Cloning, Molecular 254 STC1 32292891 Bioelectricity 2020 PMC6524654 10.1089/bioe.2018.0005 0 0 0 734 254 STC1 32273636 Nagoya J Med Sci 2020 PMC7103862 10.18999/nagjms.82.1.85 0 0 0 734 teleocalcin|Glycoproteins|Cell Line, Tumor|Cell Proliferation|Cell Movement|RNA, Messenger 254 STC1 32222972 Int. J. Cancer 2020 10.1002/ijc.32993 0 0 0 734 ANGPT2 protein, human|*Angiopoietin 2|Prospective Studies|*Colorectal Carcinoma|Microsatellite Instability|CpG Islands|Proto-Oncogene Proteins B-raf|Prognosis|DNA Methylation|Mutation|Biomarkers 254 STC1 32155780 Cells 2020 PMC7140534 10.3390/cells9030636 0 0 0 734 Humans|*Palatine Tonsil|*Reactive Oxygen Species|teleocalcin|*Mesenchymal Stem Cells|*Glycoproteins|*B Cells|Cell Differentiation|Cells, Cultured|Adipose Tissue|Mitochondria 254 STC1 32143590 BMC Ophthalmol 2020 PMC7060629 10.1186/s12886-020-01348-6 1 0 0 734 Humans|Child|*Retinoblastoma|*Etoposide|*Transcriptome|*Drug Resistance, Neoplasm|Retinal Neoplasms|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Proliferation|Cell Survival|Signal Transduction|Sequencing, RNA 254 STC1 32140959 Mol. Biol. Rep. 2020 10.1007/s11033-020-05351-4 0 0 0 734 Humans|*Multifactor Dimensionality Reduction|*Epistasis, Genetic|*Osteoarthritis, Knee|*Risk Factors|Genetic Susceptibility|SNPs|Genotypes|Gene Frequency|Articular Cartilage|Case-Control Studies|Knee Joint|Models, Genetic|Software|COL11A1 protein, human|Collagen Type XI 254 STC1 32037949 Cancer Biol. Ther. 2020 10.1080/15384047.2020.1721250 0 0 0 734 *Thyroid Gland|teleocalcin|Papillary Thyroid Cancer|Thyroid Cancer|*Glycoproteins|Carcinoma, Papillary|RNA, Micro|*Carcinogenesis|Gene Expression Regulation, Neoplastic|Carcinoma|Downregulation|Up-Regulation|Cell Movement|Cell Line, Tumor|Cell Proliferation|Protein Kinases 254 STC1 31945054 PLoS Biol. 2020 PMC6964821 10.1371/journal.pbio.3000599 15 0 0 734 Humans|*Proteomics|Longitudinal Studies|Cellular Senescence|*Aging|*Biomarkers|Phenotypes|Secretory Pathway|Baltimore 254 STC1 31889892 Cancer Cell Int. 2020 PMC6916020 10.1186/s12935-019-1062-0 0 0 0 734 Humans|Female|teleocalcin|*Sevoflurane|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Glycoproteins|*Downregulation|Cell Proliferation|Cell Movement|Cell Line, Tumor|*Disease Progression|Apoptosis|Gene Expression Regulation, Neoplastic 254 STEAP4 32409586 J. Biol. 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U.S.A. 2020 10.1073/pnas.1915386117 0 0 0 324 Humans|STIM1 protein, human|*Stromal Interaction Molecule 1|Stromal Interaction Molecule 2|*Neoplasm Proteins|ORAI1 Protein|Calcium Signaling|Calcium Channels|Endoplasmic Reticulum|Calcium|Cell Membrane|Membrane Proteins|HEK293 Cells|STIM2 protein, human|ORAI1 protein, human 299 STIM2 32576932 Sci Rep 2020 PMC7311479 10.1038/s41598-020-66961-3 0 0 0 324 Humans|*Stromal Interaction Molecule 2|*Calcium|Stromal Interaction Molecule 1|ORAI1 Protein|Endoplasmic Reticulum|Calcium Signaling|Neoplasm Proteins|Membrane Proteins|Protein Binding|*Sulfhydryl Compounds|HEK293 Cells 299 STIM2 32563861 Cell Calcium 2020 10.1016/j.ceca.2020.102227 0 0 0 324 *Calcium|Stromal Interaction Molecule 2|Stromal Interaction Molecule 1|ORAI1 Protein|Calcium Signaling|Calcium Channels|*Calcium, Dietary|Endoplasmic Reticulum|Membrane Glycoproteins|T Cells|B Cells|Carrier Proteins 299 STIM2 32556706 Pflugers Arch. 2020 10.1007/s00424-020-02405-1 0 0 0 324 ORAI1 Protein|Stromal Interaction Molecule 1|Calcium Channels|Calcium|Neoplasm Proteins|Transcription Factors|Upregulation|Alkaline Phosphatase 299 STIM2 32315120 Ann Clin Transl Neurol 2020 PMC7261755 10.1002/acn3.51040 0 0 0 324 Humans|*Migraine with Aura|*Migraine|Juvenile Myoclonic Epilepsy|Photosensitive Epilepsy|Pedigree|Phenotypes|*Translocation, Genetic 299 STIM2 32222058 Aging Cell 2020 PMC7253057 10.1111/acel.13144 1 0 0 324 Mice|Animals|*Alzheimer Disease|*Mossy Fibers, Hippocampal|*Memory|Amyloid beta-Protein Precursor|*Disease Models, Animal|Synapses|Dendritic Spines|Hippocampus|Synaptic Transmission|*Inhibition, Psychological|*B-Lymphocytes|MicroRNAs|Stim2 protein, mouse|Stromal Interaction Molecule 2 299 STIM2 32186932 Am. 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Otorinolaringol. 2020 10.17116/otorino20208502114 0 0 0 12 *Deafness|*Hearing Loss|*Mutations|Hearing Loss, Sensorineural|Connexins|Connexin 26|Membrane Proteins|Sequence Deletion|Polymorphism, Single Nucleotide 100 STRC 32388790 Mol. Cell. Biochem. 2020 10.1007/s11010-020-03742-6 0 0 0 12 Humans|*Myocytes, Cardiac|*Cell Differentiation|Stem Cells|*Electrical Stimulation|Cell Proliferation 100 STRC 32203226 Genet. Med. 2020 10.1038/s41436-020-0774-9 0 0 0 12 Child|Humans|Hearing Loss, Sensorineural|*Hearing Loss|Genetic Testing|Connexins|DNA Copy Number Variations|Mutation|Membrane Proteins 100 STRC 32112830 Int. J. Biol. Macromol. 2020 10.1016/j.ijbiomac.2020.02.295 0 0 0 12 graphene oxide|*Silver|*Polyurethanes|*Nanofibers|*Curcumin|acetylcellulose|Metal Nanoparticles|*Graphene|*Nanocomposites|disilver oxide|*Silver Compounds|*Oxides|*Anti-Bacterial Agents|*Cellulose|*Anti-Infective Agents|Microbial Sensitivity Tests|Bandages|Staphylococcus aureus 100 STRC 32000839 Genome Med 2020 PMC6993336 10.1186/s13073-020-0712-0 1 0 0 12 *Exome|*Workflow|*DNA Copy Number Variations|*Whole Exome Sequencing|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|Algorithms 100 STRC 31992338 Orphanet J Rare Dis 2020 PMC6986010 10.1186/s13023-020-1311-2 1 0 0 12 Humans|*Molecular Epidemiology|*Alleles|*Mutations|Connexins|Deafness|Connexin 26|*Asian Continental Ancestry Group|Hearing Loss|Heterozygote|Hearing Loss, Sensorineural 100 STRC 31985074 Laryngoscope 2020 10.1002/lary.28536 0 0 0 12 Infant, Newborn|Child|Humans|*Cytomegalovirus|*Hearing Loss, Bilateral|*Hearing Loss, Sensorineural|Cytomegalovirus Infections|*Deafness|*Genetic Testing|Hearing Tests|Hearing Loss|Neonatal Screening 100 STRC 31896519 Eur. J. Cancer 2020 10.1016/j.ejca.2019.10.021 0 0 0 12 Humans|Adult|PM 01183|*Sarcoma|*Carbolines|*Heterocyclic Compounds, 4 or More Rings|Soft Tissue Neoplasms|Leiomyosarcoma|gemcitabine|Deoxycytidine|Disease-Free Survival|Antineoplastic Agents|Sarcoma, Synovial|Liposarcoma, Myxoid|Anthracyclines|Doxorubicin|Antineoplastic Combined Chemotherapy Protocols|Progression-Free Survival|Antibiotics, Antineoplastic|STRC protein, human 100 STYX 32472731 FEBS J. 2020 10.1111/febs.15426 0 0 0 164 *Phosphatases, MAPK|Mitogen-Activated Protein Kinases|Apoptosis Regulatory Proteins|Intracellular Signaling Peptides and Proteins|MAP Kinase Signaling System|Phosphorylation|Nuclear Proteins|Signal Transduction|Cell Differentiation|Protein Binding|Neurite|HDAC6 protein, human|Histone Deacetylase 6|Apoptosis 64 STYX 32239181 Biosci. Rep. 2020 PMC7167255 10.1042/BSR20200057 0 0 0 164 Humans|Female|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|*Endometrial Cancer|Cell Proliferation|Apoptosis|Downregulation|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Phosphorylation|STYX protein, human|Nuclear Proteins|Intracellular Signaling Peptides and Proteins 64 SULF1 32611237 Circ. Res. 2020 10.1161/CIRCRESAHA.119.315999 0 0 0 390 231 SULF1 32432744 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202005_21170 0 0 0 390 *Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|*Cell Proliferation|*Apoptosis|MicroRNAs|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|RNA, Small Interfering 231 SULF1 32413029 PLoS ONE 2020 PMC7228113 10.1371/journal.pone.0230354 0 0 0 390 Humans|Male|perlecan|*Heparan Sulfate Proteoglycans|Neoplasm Recurrence, Local|*Prostate|*Prostatic Neoplasms|*Macrophage|*Extracellular Matrix Proteins|Tumor Microenvironment|Cancer-Associated Fibroblasts|Cell Proliferation|Cell Line, Tumor|*Bone Neoplasms|Fibroblasts|Bone Marrow Stromal Cells|Bone Marrow|SULF1 protein, human|Sulfotransferases|WNT3A protein, human 231 SULF1 32398079 Hum. Genomics 2020 PMC7218574 10.1186/s40246-020-00264-6 0 0 0 390 Humans|*Heparan Sulfate Proteoglycans|Genome-Wide Association Study|*Multiple Sclerosis|Australia|SDC2 protein, human|*Heparan Sulfate Proteoglycan Core Protein|Heparitin Sulfate|Syndecans|*European Continental Ancestry Group|Glypicans|Sulfotransferases|Cell Differentiation|Single Nucleotide Polymorphisms|Cell Membrane|Case-Control Studies|GPC5 protein, human 231 SULF1 32200436 Med. Oncol. 2020 10.1007/s12032-020-1339-0 0 0 0 390 Gene Modules|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Gene Expression|Pancreatic Cancer|*Pancreas 231 SULF1 32135645 Zhonghua Zhong Liu Za Zhi 2020 10.3760/cma.j.issn.0253-3766.2020.02.006 0 0 0 390 231 SULF1 32038163 Front Mol Neurosci 2020 PMC6985096 10.3389/fnmol.2019.00333 0 0 0 390 Animals|Mice|*Pyramidal Tracts|SULF2 protein, human|*Sulfotransferases|*Axons|*Heparitin Sulfate|Axon Guidance|Signal Transduction|Brain|Sulf1 protein, mouse|Sulf2 protein, mouse|Sulfatases 231 SULF1 32034099 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7049147 10.1073/pnas.1913481117 2 0 0 390 *Histone|Endothelial Cells|Signal Transduction|Epithelial-Mesenchymal Transition|Cells, Cultured|Histone Demethylases 231 SULF1 32031713 J Eur Acad Dermatol Venereol 2020 10.1111/jdv.16264 0 0 0 390 *Hidradenitis Suppurativa|*Apocrine Glands|Skin 231 SULF1 31921422 Biomark Res 2020 PMC6950830 10.1186/s40364-019-0180-0 0 0 0 390 Mesothelioma, Malignant|*Mesothelioma|Pleural Neoplasms|*Lung Neoplasms|Asbestos|GPI-Linked Proteins|Pleura|Biomarkers, Tumor|ROC Curve|Extracellular Matrix Proteins|Occupational Exposure 231 SULF1 31898662 J Cancer Res Ther 2020 10.4103/jcrt.JCRT_194_17 0 0 0 390 Female|Humans|Mice|Animals|*Up-Regulation|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|Cell Line, Tumor|Lymphatic Metastasis|Cell Movement|RNA, Small Interfering|Transfection|*Transcriptional Activation|RNA, Messenger|Sulfatases 231 SULF2 32564518 Clin Transl Med 2020 10.1002/ctm2.108 0 0 0 302 *Herpesvirus 1, Human|*Depression|United Kingdom|*Biological Specimen Banks|Herpes Simplex|Herpesvirus 2, Human|Herpes Genitalis|Logistic Models 169 SULF2 32413029 PLoS ONE 2020 PMC7228113 10.1371/journal.pone.0230354 0 0 0 302 Humans|Male|perlecan|*Heparan Sulfate Proteoglycans|Neoplasm Recurrence, Local|*Prostate|*Prostatic Neoplasms|*Macrophage|*Extracellular Matrix Proteins|Tumor Microenvironment|Cancer-Associated Fibroblasts|Cell Proliferation|Cell Line, Tumor|*Bone Neoplasms|Fibroblasts|Bone Marrow Stromal Cells|Bone Marrow|SULF1 protein, human|Sulfotransferases|WNT3A protein, human 169 SULF2 32101585 PLoS ONE 2020 PMC7043740 10.1371/journal.pone.0229495 2 0 0 302 *Lipemia|*Postprandial Period|Apolipoprotein A-V|Apolipoproteins A|Triglycerides|Apolipoprotein C-III|Cholesterol, HDL|Apolipoprotein A-I|Gene Frequency|Linkage Disequilibrium|Genotype|Polymorphism, Single Nucleotide 169 SULF2 32049100 Braz. J. Med. Biol. Res. 2020 PMC7006129 10.1590/1414-431X20198901 0 0 0 302 Humans|Mice|Female|Animals|*Proto-Oncogene Proteins c-akt|*Uterine Cervical Neoplasms|HeLa Cells|Mice, Nude|*Signal Transduction|*Apoptosis|*Tumorigenesis|Phosphatidylinositol 3-Kinases|SULF2 protein, human|*Sulfotransferases|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|*Cell Transformation, Neoplastic|Cell Proliferation|Cell Movement|CCND1 protein, human|Cyclin D1|Cell Line, Tumor 169 SULF2 32038163 Front Mol Neurosci 2020 PMC6985096 10.3389/fnmol.2019.00333 0 0 0 302 Animals|Mice|*Pyramidal Tracts|SULF2 protein, human|*Sulfotransferases|*Axons|*Heparitin Sulfate|Axon Guidance|Signal Transduction|Brain|Sulf1 protein, mouse|Sulf2 protein, mouse|Sulfatases 169 SULF2 31988246 J. Biol. Chem. 2020 PMC7049957 10.1074/jbc.RA119.011146 1 0 0 302 Humans|Mice|Animals|Carcinoma, Hepatocellular|*Zinc Finger Protein GLI1|Liver Neoplasms|STAT3 protein, human|*STAT3 Transcription Factor|SULF2 protein, human|*Sulfotransferases|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Cell Movement|Signal Transduction|*Carcinogenesis|Sulfatases|Liver|GLI1 protein, human|Sulf2 protein, mouse 169 SVOP 32605609 BMC Ophthalmol 2020 PMC7325566 10.1186/s12886-020-01528-4 0 0 0 115 Humans|*Saccades|Visual Field Tests|*Glaucoma|Visual Fields|Eye Movements|*Tetrahymenina 26 SVOP 32512180 Biochim Biophys Acta Proteins Proteom 2020 10.1016/j.bbapap.2020.140463 0 0 0 115 Humans|Rats|Animals|*Rats, Inbred F344|*D-Amino-Acid Oxidase|Amino Acids|Stereoisomerism|Brain Chemistry|Serine 26 SVOP 32176619 Aging (Albany NY) 2020 PMC7138548 10.18632/aging.102922 0 0 0 115 Rats|Animals|*Monocrotaline|*Familial Primary Pulmonary Hypertension|Hypertension, Pulmonary|Hypertrophy, Right Ventricular|*Hypertension, Pulmonary Arterial|Pulmonary Artery|*Chemokines|Inflammation|Sequencing, RNA|Disease Models, Animal 26 SWAP70 32404198 BMC Cancer 2020 PMC7222508 10.1186/s12885-020-06909-y 0 0 0 162 Humans|*Cetuximab|*Proto-Oncogene Proteins p21(ras)|*Transcriptome|*Colorectal Cancer|ras Proteins|Proto-Oncogene Proteins B-raf|Proto-Oncogene Proteins|Mutations|Antibodies, Monoclonal, Humanized|Antineoplastic Agents|Drug Resistance, Neoplasm|Antibodies, Monoclonal|Treatment Outcome|KRAS protein, human 81 SWAP70 32373157 Front Genet 2020 PMC7186505 10.3389/fgene.2020.00320 0 0 0 162 *Coronary Artery Disease|Genome-Wide Association Study|Linkage Disequilibrium|Gene Regulatory Networks|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Quantitative Trait Loci|Signal Transduction 81 SWAP70 31948317 RNA Biol 2020 PMC7237138 10.1080/15476286.2020.1713538 0 0 0 162 Animals|*Marek Disease|*Chickens|*RNA, Circular|Herpesvirus 2, Gallid|*Tumorigenesis|RNA, Micro|lncRNA|Poultry Diseases|mRNA|Transcriptome|*Cell Transformation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Sequencing, RNA|Splenic Neoplasms|Neoplasms|Cell Proliferation 81 synpo 32596561 ACS Omega 2020 PMC7315423 10.1021/acsomega.9b03952 0 0 0 489 *Size Exclusion Chromatography|Molecular Weight|Polymers 231 synpo 32398370 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7260972 10.1073/pnas.1917597117 0 0 0 489 Mice|Animals|*Butyrate|*Actins|*Intestines|*Microbiota|Intestinal Mucosa|Dysbiosis|Tight Junction|Colon|SYNPO protein, human|*Microfilament Proteins|Short-Chain Fatty Acids|Inflammatory Bowel Diseases|*Homeostasis|Cell Lines 231 synpo 32238860 Exp. Mol. Med. 2020 PMC7210307 10.1038/s12276-020-0410-4 0 0 0 489 *Podocytes|Nephrosis, congenital|Nephrotic Syndrome|RHOA protein, human|rhoA GTP-Binding Protein|Kidney Glomerulus|rho GTPases|cdc42 GTP-Binding Protein|phospholipase C epsilon|Phosphoinositide Phospholipase C|rac1 GTP-Binding Protein|Cell Migration|Mutations|Kidney Diseases|*Cell Differentiation|Cell Proliferation 231 TARBP1 32213663 Aging (Albany NY) 2020 PMC7138582 10.18632/aging.102969 1 0 0 41 Humans|*Carcinoma, Hepatocellular|*Computational Biology|*Liver Neoplasms|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Upregulation|Prognosis|Gene Expression Profiling|Databases, Genetic|mRNA|Disease-Free Survival|Disease Progression 26 TARBP1 32200387 Med. Sci. Monit. 2020 PMC7111148 10.12659/MSM.920854 0 0 0 41 *Carcinoma, Hepatocellular|*Liver Cancer|*Prognosis|Bioinformatics|*Disease Progression|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Databases, Genetic|Transcriptome|Receiver Operating Characteristic|Algorithms 26 TARBP1 31957540 RNA Biol 2020 PMC7237164 10.1080/15476286.2019.1708549 2 0 0 41 Humans|*Methyltransferases|*RNA|*Neoplastic Processes|*Disease Progression|DNA Copy Number Variations|Cell Line, Tumor|Genomics|Methylation|Cell Proliferation|Mutation 26 TBX2 32466750 BMC Mol Cell Biol 2020 PMC7257154 10.1186/s12860-020-00282-1 0 0 0 496 *Activin|*Germ Layer|Brachyury protein|T-Box Domain Proteins|Ectoderm|*Signal Transduction|Mesoderm|Endoderm|Smad2 Protein|DNA-Binding Proteins|Xenopus Proteins|Transcription Factors|Transforming Growth Factor beta|Fetal Proteins|Gene Expression Regulation, Developmental|Trans-Activators|Cell Differentiation 339 TBX2 32271423 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202003_20670 0 0 0 496 339 TBX2 32264809 Comb. 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Vis. 2020 PMC7316632 0 0 0 438 Humans|*Endothelial Cells|*DNA Methylation|*B-DNA|*Glaucoma|*Endothelium|Trabecular Meshwork|*Sclera|Intraocular Pressure|Aqueous Humor|*Tetrahymenina|Glaucoma, Primary Open Angle|Epigenesis, Genetic|Cells, Cultured 627 TGFBR3 32569368 Endocrinology 2020 10.1210/endocr/bqaa099 0 0 0 438 Female|inhibin A|inhibin B|*Inhibins|activin B|Activins|activin A|inhibin beta A subunit|Inhibin-beta Subunits|betaglycan|Proteoglycans|Receptors, Transforming Growth Factor beta|Follicle Stimulating Hormone|Activin Receptors|Gonadotrophs|Protein Binding|Corpus Luteum|Ovarian Follicle|*Gonadal Hormones 627 TGFBR3 32514165 Mod. Pathol. 2020 10.1038/s41379-020-0580-6 0 0 0 438 Middle Aged|Adult|Humans|Comparative Genomic Hybridization|*Fibrosarcoma|Soft Tissue Neoplasm|betaglycan|Receptors, Transforming Growth Factor beta|Proteoglycans|Lipoma|Gene Rearrangement|Hyaluronoglucosaminidase|In Situ Hybridization, Fluorescence|Antigens, Neoplasm|Histone Acetyltransferases|Translocation, Genetic|Hemosiderosis|Biomarkers, Tumor 627 TGFBR3 32493078 Int. J. Surg. Pathol. 2020 10.1177/1066896920930799 0 0 0 438 *Soft Tissue Neoplasms|*Lipoma|Sarcoma|Hemosiderosis|Hyaluronoglucosaminidase|Antigens, Neoplasm|Receptors, Transforming Growth Factor beta|Gene Rearrangement|Proteoglycans|Histone Acetyltransferases|In Situ Hybridization, Fluorescence|Translocation, Genetic|Biomarkers, Tumor|Foot 627 TGFBR3 32491253 Mol Oncol 2020 10.1002/1878-0261.12737 0 0 0 438 Humans|Female|*Uterine Cervical Neoplasms|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|betaglycan|E6 protein, Human papillomavirus type 18|Oncogene Proteins, Viral|*Receptors, Transforming Growth Factor beta|E6 protein, Human papillomavirus type 16|*Proteoglycans|*Disease Progression|MicroRNAs|Gene Expression Regulation, Neoplastic|Repressor Proteins|Cell Proliferation|Carcinoma, Squamous Cell|Cell Line, Tumor|Exosomes|Cell Movement 627 TGFBR3 32471132 Cancers (Basel) 2020 PMC7352722 10.3390/cancers12061375 0 0 0 438 betaglycan|*Receptors, Transforming Growth Factor beta|*Proteoglycans|*Genes, Tumor Suppressor|Cell Movement|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Proliferation|*Head and Neck Cancer|Downregulation|Cell Line, Tumor|*Lymphatic Metastasis|Lymph Nodes 627 TGFBR3 32441533 Syst Biol Reprod Med 2020 10.1080/19396368.2020.1759730 0 0 0 438 Humans|Female|*Prognosis|*Module, Gene|Neoplasm Recurrence, Local|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Cancer Stem Cells|*Ovary|Drug Resistance, Neoplasm|Biomarkers, Tumor|Cell Line, Tumor 627 TGFBR3 32368260 Anim Reprod 2020 PMC7189511 10.21451/1984-3143-AR2018-0146 0 0 0 438 Female|Cattle|Animals|*Luteolysis|*Transforming Growth Factor beta|Corpus Luteum|Dinoprost|Granulosa Cells|mRNA|Signal Transduction|Transforming Growth Factors 627 TGFBR3 32266715 J. Comp. Neurol. 2020 10.1002/cne.24921 0 0 0 438 Humans|*Depressive Disorder, Major|*Bipolar Disorder|*Chromosomes, Human, Pair 1|*Schizophrenia|SNPs|Genetic Predisposition to Disease|Genome-Wide Association Study|Genotype|Case-Control Studies|Cohort Studies|Psychosis|China|ELTD1 protein, human|NR5A2 protein, human|Receptors, Cytoplasmic and Nuclear|FAM5C protein, human|HHAT protein, human|Acyltransferases 627 TGFBR3 32189110 Histochem. Cell Biol. 2020 PMC7343741 10.1007/s00418-020-01866-w 0 0 0 438 Swine|Animals|*In Vitro Oocyte Maturation Techniques|Oocytes|Oogenesis|*Signal Transduction|Transcriptome|Oligonucleotide Array Sequence Analysis|Gene Ontology|Gene Expression Profiling|Brilliant Cresyl Blue|Oxazines|*Biological Phenomena|Genes, cdc|*Lipids 627 TGFBR3 32160576 Theriogenology 2020 10.1016/j.theriogenology.2020.02.044 0 0 0 438 Swine|Female|Animals|*Longevity|*Granulosa Cells|Ovarian Follicle|Oogenesis|*Cell Proliferation|Oocytes|Ovaries|*Programmed Cell Death|*Aging|*Cell Cycle|Cell Differentiation|Transcriptome|*Disease Models, Animal|Gene Expression Profiling|Cells, Cultured|Upregulation|Sus scrofa 627 TGFBR3 31989994 Med. Sci. Monit. 2020 PMC7001513 10.12659/MSM.919311 2 0 0 438 *Alzheimer Disease|Neurodegenerative Diseases|MIRN93 microRNA, human|miRNAs|Gene Ontology|Bioinformatics|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Transcriptome|Protein Interaction Mapping|mRNA|*Hippocampus|Downregulation|Upregulation 627 TGFBR3 31922278 J. Orthop. Res. 2020 10.1002/jor.24585 0 0 0 438 Female|*Introns|*Anterior Cruciate Ligament|*Anterior Cruciate Ligament Injuries|Genotype|Study, Genetic Association|Genetic Susceptibility|*Exon|Type V Collagen|Ruptures|Allele|Gene Frequency|Haplotypes|Case-Control Study|betaglycan|Proteoglycans|*Transforming Growth Factor|Extracellular Matrix|Receptors, Transforming Growth Factor beta 627 TGFBR3 31898851 Genes Chromosomes Cancer 2020 10.1002/gcc.22832 0 0 0 438 Nerve Tissue Proteins|Receptors, Immunologic|*Fibrosarcoma|Soft Tissue Neoplasms|betaglycan|Receptors, Transforming Growth Factor beta|Proteoglycans|Sarcomas|Lipoma|Translocation, Genetic|Gene Rearrangement|In Situ Hybridization, Fluorescence|Hyaluronoglucosaminidase|Antigens, Neoplasm|Histone Acetyltransferases|Hemosiderosis|Biomarkers, Tumor|High-Throughput Nucleotide Sequencing 627 TIMD4 32187802 J Gene Med 2020 10.1002/jgm.3186 0 0 0 299 *Wnt Pathway|*Lymphoma, Large B-Cell, Diffuse|*Apoptosis|beta Catenin|*Catenins|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Nucleus|RNA, Messenger 81 TIMD4 32115487 J. 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Thromb. 2020 10.5551/jat.51540 0 0 0 299 Adult|Humans|Japan|*Hypertriglyceridemia|Apolipoprotein A-V|Apolipoprotein CII|Lipoprotein Lipase|*Hyperlipidemias|Receptors, Lipoprotein|Apolipoproteins A|Heterozygote|Membrane Proteins|*Lipids|GPIHBP1 protein, human 81 TIMD4 32020709 Cell Prolif. 2020 PMC7106962 10.1111/cpr.12776 2 0 0 299 *Carcinoma, Non-Small-Cell Lung|*Interleukin-6|*Lung Neoplasms|*Up-Regulation|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|MicroRNAs|*Neoplastic Processes|Cell Line, Tumor|Cell Proliferation|*Transcriptional Activation|Signal Transduction 81 TIMP3 32648125 Pflugers Arch. 2020 10.1007/s00424-020-02432-y 0 0 0 1458 Humans|Rats|Animals|*Diabetic Retinopathy|Endothelial Cells|Diabetes Mellitus, Experimental|TIMP3 protein, human|*TIMP-3|Retina|MicroRNAs|Upregulation|Apoptosis|Signal Transduction|MIRN221 microRNA, human|MIRN221 microRNA, rat 1048 TIMP3 32631441 Acta Neuropathol Commun 2020 PMC7336459 10.1186/s40478-020-00972-z 0 0 0 1458 Humans|*Matrix Metalloproteinase 9|*Cerebral Amyloid Angiopathy|*Cerebral Hemorrhage|TIMP3 protein, human|*TIMP-3|Brain|Amyloid beta-Peptides|Risk Factor|MMP9 protein, human 1048 TIMP3 32619670 Acta Biomater 2020 10.1016/j.actbio.2020.06.037 0 0 0 1458 Animals|Mice|*Mesenchymal Stem Cells|*Animals, Newborn|*Microglia|*Extracellular Vesicles|*Hypoxia|*Brain|*Ischemia|*Macrophage Activation|*B-Lymphocytes|*Protective Agents|MicroRNAs|Brain Injuries|Apoptosis|Cells, Cultured|Disease Models, Animal|Macrophages 1048 TIMP3 32612540 Front Physiol 2020 PMC7308558 10.3389/fphys.2020.00661 0 0 0 1458 TIMP3 protein, human|*Tissue Inhibitor of Metalloproteinase-3|Matrix Metalloproteinases|Thrombospondin 1048 TIMP3 32542727 Prostate 2020 10.1002/pros.24029 0 0 0 1458 Humans|Male|*Resveratrol|*Prostate|TIMP2 protein, human|*TIMP-2|*Upregulation|DNA Methylation|5-Methylcytosine|Proto-Oncogene Proteins|Mixed Function Oxygenases|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|*Prostate Cancer|*Neoplastic Processes|Cell Line, Tumor|TET1 protein, human 1048 TIMP3 32518385 Sci Rep 2020 PMC7283274 10.1038/s41598-020-66233-0 0 0 0 1458 Mice|Animals|*Cartilage, Articular|TIMP3 protein, human|*Tissue Inhibitor of Metalloproteinase-3|aggrecanase|*Osteoarthritis|*Endopeptidases|Chondrocyte|*Disease Models, Animal|Type II Collagen|MMP Inhibitors|Mice, Transgenic|Matrix Metalloproteinases 1048 TIMP3 32507001 RNA Biol 2020 10.1080/15476286.2020.1777767 0 0 0 1458 *Nerve Regeneration|*Axons|Peripheral Nerve Injury|*Cell Proliferation|Schwann Cells|Sciatic Neuropathy|Sciatic Nerve|Dorsal Root Ganglion|Cell Movement|MicroRNAs|Neurons|*Neurogenesis 1048 TIMP3 32502021 Medicine (Baltimore) 2020 PMC7306288 10.1097/MD.0000000000020552 0 0 0 1458 Humans|*Essential Hypertension|*Asian Continental Ancestry Group|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Alleles|Haplotypes|Genotype|*Smoking|Hypertension|*Tobacco Smoking|Case-Control Studies|Risk Factors 1048 TIMP3 32466334 Int J Mol Sci 2020 PMC7279350 10.3390/ijms21103735 0 0 0 1458 1048 TIMP3 32456486 Scand. J. Gastroenterol. 2020 10.1080/00365521.2020.1766552 0 0 0 1458 1048 TIMP3 32434555 Stem Cell Res Ther 2020 PMC7238576 10.1186/s13287-020-01706-7 0 0 0 1458 Humans|Horses|Animals|*Mesenchymal Stem Cells|*Interleukin 1|*Bone Marrow|*Chondrogenesis|*Cell Differentiation|*Mass Spectrometry|Osteoarthritis 1048 TIMP3 32432759 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202005_21187 0 0 0 1458 *Podocytes|TIMP3 protein, human|*TIMP-3|*Upregulation|*Apoptosis|RNA, Long Noncoding|MicroRNAs|RNA Interference|Cell Proliferation|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|Cell Movement|*Inflammation|Epithelial-Mesenchymal Transition|3' Untranslated Regions|Cell Line, Tumor|*Transcriptional Activation|Diabetic Nephropathy 1048 TIMP3 32422429 J. Surg. Res. 2020 10.1016/j.jss.2020.03.043 0 0 0 1458 *Keratinocytes|TIMP3 protein, human|*TIMP-3|*Downregulation|Cell Movement|MicroRNAs|Cell Proliferation|Upregulation|Signal Transduction 1048 TIMP3 32407518 Invest. Ophthalmol. Vis. Sci. 2020 10.1167/iovs.61.5.17 0 0 0 1458 *Genetic Predisposition to Disease|Retinal Drusen|Macular Degeneration|Complement Factor H|Polymorphism, Single Nucleotide|*Disease Progression|Phenotype|Diet, Mediterranean|*Retina|Risk Factors 1048 TIMP3 32397602 Biomedicines 2020 PMC7277193 10.3390/biomedicines8050116 0 0 0 1458 *Matrix Metalloproteinases|*Epigenomics|*DNA Methylation|CpG Islands|Promoter Regions, Genetic|cytidylyl-3'-5'-guanosine|*Dinucleoside Phosphates|Tissue Inhibitor of Metalloproteinase-3|Gene Expression Regulation, Neoplastic 1048 TIMP3 32330537 Gene 2020 10.1016/j.gene.2020.144700 0 0 0 1458 Humans|*Interleukin-6|*Laryngeal Neoplasms|Single Nucleotide Polymorphisms|TIMP3 protein, human|*TIMP-3|Genetic Predisposition to Disease|IL1RL1 protein, human|*Interleukin-1 Receptor-Like 1 Protein|Genetic Association Studies|*Squamous Cell Carcinoma of Head and Neck|Gene Frequency|Genotype|Carcinoma, Squamous Cell|Case-Control Studies|Head and Neck Neoplasms|IL1RAP protein, human|Interleukin-1 Receptor Accessory Protein|BLK protein, human 1048 TIMP3 32309847 Biosci. Rep. 2020 PMC7189364 10.1042/BSR20193653 1 0 0 1458 *Diabetic Nephropathies|*Podocytes|TIMP3 protein, human|*TIMP-3|*Apoptosis|MicroRNAs|*Inflammation|Down-Regulation|Glucose|Signal Transduction|Diabetes Mellitus 1048 TIMP3 32306499 Liver Int. 2020 10.1111/liv.14476 0 0 0 1458 *Hepatic Stellate Cells|*miRNAs|TIMP3 protein, human|*TIMP-3|Fibrosis, Liver|Liver|*Liver Diseases|Gene Expression Profiling|Gene Expression Regulation|Cell Proliferation|Cells, Cultured 1048 TIMP3 32271187 Am. J. Surg. Pathol. 2020 10.1097/PAS.0000000000001481 0 0 0 1458 1048 TIMP3 32246022 Sci Rep 2020 PMC7125089 10.1038/s41598-020-62572-0 0 0 0 1458 Humans|*Keratoconus|*Chinese|DNA Mutational Analysis|Mutation|TIMP3 protein, human|TIMP-3|*Extracellular Matrix|Sequencing, Next-Generation 1048 TIPARP 32679093 Cell Chem Biol 2020 10.1016/j.chembiol.2020.06.009 0 0 0 455 *Poly(ADP-ribose) Polymerase Inhibitors|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|Poly ADP Ribose Polymerase|Poly Adenosine Diphosphate Ribose|Nicotinamide Adenine Dinucleotide 59 TIPARP 32482854 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7306777 10.1073/pnas.1921815117 0 0 0 455 Mice|Animals|*Cell Nucleus|*Hypoxia-Inducible Factor 1|ADP Ribosyltransferase|ADP Ribosylation|Poly(ADP-ribose) Polymerases|Receptors, Aryl Hydrocarbon|*Cell Transformation, Neoplastic|*Tumorigenesis|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Gene Expression Regulation|Ubiquitination|E3 Ubiquitin Ligase 59 TIPARP 32169417 Biochem. Pharmacol. 2020 10.1016/j.bcp.2020.113905 0 0 0 455 AHR protein, human|*Receptors, Aryl Hydrocarbon|*NAD|*Basic Helix-Loop-Helix Transcription Factors|Polychlorinated Dibenzodioxins|Poly(ADP-ribose) Polymerases|Signal Transduction 59 tiprl 32104250 Exp Ther Med 2020 PMC7027157 10.3892/etm.2019.8358 0 0 0 1859 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Epithelial-Mesenchymal Transition|*Cell Migration|A549 Cells|CDH1 protein, human|Cadherins|Vimentin|Prognosis|RNA, Long Noncoding|Cell Proliferation|Cell Line, Tumor|Signal Transduction|Antigens, CD|*Neoplastic Processes 34 tiprl 32039845 J. Alzheimers Dis. 2020 PMC7175932 10.3233/JAD-190948 0 0 0 1859 Animals|*Alzheimer Disease|*Amyloid|Amyloid beta-Peptides|Amyloid beta-Protein Precursor|*Brain|*Amyloidosis|*Amyloidogenic Proteins|Autophagy|Disease Models, Animal|*Gene Expression 34 TKT 32659474 Eur. J. Cancer 2020 10.1016/j.ejca.2020.04.049 0 0 0 1757 Melanoma, Cutaneous Malignant|*Melanoma|Skin Cancers|*NADP|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Kaplan-Meier Estimate|Genotype|Prognosis 270 TKT 32636717 Clin Proteomics 2020 PMC7331219 10.1186/s12014-020-09288-5 0 0 0 1757 Humans|*Peptides|Spectrometry, Mass, Electrospray Ionization|Chromatography, Liquid|Tandem Mass Spectrometry|Proteomics|Proteins|*Plasma|Amino Acid Sequence|*Sepsis 270 TKT 32524041 Epilepsia Open 2020 PMC7278540 10.1002/epi4.12382 0 0 0 1757 Humans|*Epilepsy|*Brain|Refractory Epilepsy|Seizures|Implantable Neurostimulators|Deep Brain Stimulation|Electrodes, Implanted|Electroencephalography|Vagus Nerve Stimulation|Thalamus 270 TKT 32466928 Food Res. Int. 2020 10.1016/j.foodres.2020.109137 0 0 0 1757 *Zygosaccharomyces|*Fructose|Chromatography, Liquid|Tandem Mass Spectrometry|*Pentosephosphate Pathways|Saccharomyces cerevisiae|Flavoring Agents|Furans|HPLC|ribulose 5-phosphate|Ribulosephosphates 270 TKT 32421920 Vet Comp Oncol 2020 10.1111/vco.12610 0 0 0 1757 Female|Dogs|Animals|*Mammary Neoplasms, Animal|*Proteomics|Chromatography, Liquid|Tandem Mass Spectrometry|Dog Diseases|Carcinoma|*Cells, Epithelial|Mammary Glands, Animal|Biomarkers, Tumor|*Electrophoresis 270 TKT 32295803 Diabetes 2020 10.2337/db19-1087 1 0 0 1757 Animals|Mice|*Lipolysis|*Transketolase|*Adipose Tissue|*Obesity|Adipocytes|Diet, High-Fat|Insulin Resistance|Fatty Liver|Lipid Metabolism|Energy Expenditure|*Protective Agents|Pentosephosphate Pathway|Glycolysis|Glucose 270 TKT 32205206 Ann. Anat. 2020 10.1016/j.aanat.2020.151484 0 0 0 1757 *Dental Implants|*Connective Tissue|*Collagen|Gingiva|Mouth Mucosa 270 TKT 31994802 J Anim Physiol Anim Nutr (Berl) 2020 10.1111/jpn.13313 1 0 0 1757 Pregnancy|Humans|Cattle|Animals|Female|Lactation|Milk|Dietary Supplements|Parity|Folic Acid|Animal Feed|Diet|Postpartum Period|Energy Metabolism|3-Hydroxybutyric Acid|Fatty Acids, Nonesterified|*Parturition 270 TKT 31949131 Cell Death Dis 2020 PMC6965636 10.1038/s41419-020-2225-6 0 0 0 1757 *Transketolase|*Carcinoma, Hepatocellular|histone deacetylase 3|*Liver Cancer|*Histone Deacetylases|ribose-5-phosphate|Ribosemonophosphates|Liver|*Promoter Regions, Genetic|Pentosephosphate Pathway|Bile Acids|Cell Line, Tumor|*Gene Expression|DNA Damage 270 TLE6 32613414 J. Assist. Reprod. Genet. 2020 10.1007/s10815-020-01871-x 0 0 0 17 Female|Sheep|Animals|*Oocyte|Embryogenesis|Blastocyst|Zygote|Gene Expression Regulation, Developmental|Transcription Factors|Cytoplasm|Maternal Age 23 TLE6 32172300 Hum. Genet. 2020 10.1007/s00439-020-02143-5 0 0 0 17 Pregnancy|Humans|Female|Infertility, Female|*Abortion, Habitual|Sequencing, Whole Exome|Fertilization in Vitro|*Genomics|Fertility|Genetic Predisposition to Disease|Reproduction|Mutation|Cohort Studies|Tle6 protein, human|Transcription Factors|CENPH protein, human|Chromosomal Proteins, Non-Histone 23 TLE6 31897846 J. Assist. Reprod. Genet. 2020 PMC7056779 10.1007/s10815-019-01653-0 0 0 0 17 Humans|Female|*Infertility, Female|Intracytoplasmic Sperm Injection|Fertilization in Vitro|*Mutations|Oocytes|Phenotype|Tle6 protein, human|Transcription Factors 23 tlr3 32664712 J. Biol. Regul. Homeost. Agents 2020 10.23812/20-80-A-29 0 0 0 2959 4373 tlr3 32660087 Cells 2020 10.3390/cells9071653 0 0 0 2959 *Peptidoglycan|*Macrophages, Alveolar|*Superinfection|*Streptococcus pneumoniae|*Respiratory Syncytial Virus, Human|Lactobacillus rhamnosus|Pneumococcal Infections|Lung|*Cell Wall|Cytokines|Probiotics 4373 tlr3 32660060 Cells 2020 10.3390/cells9071648 0 0 0 2959 Mice|Animals|*Disease Models, Animal|*Toll-Like Receptors|*Endosomes|Toll-Like Receptor 4|Toll-Like Receptor 2|Signal Transduction|CPG-oligonucleotide|Oligodeoxyribonucleotides|Toll-Like Receptor 9|Poly I-C|NF-kappa B|Lipopolysaccharides|Tumor Necrosis Factor-alpha|Mitogen-Activated Protein Kinases|*Inflammation|Cytokines|Membrane Glycoproteins|Phosphorylation 4373 tlr3 32656248 Front Vet Sci 2020 PMC7325983 10.3389/fvets.2020.00246 0 0 0 2959 Animals|Swine|*Soybeans|*Zea mays|*Secretory Immunoglobulin A|Animal Feed|Animal Nutritional Physiological Phenomena|Diet|*Fermentations|*Fabaceae|Digestion|*Fermentors|Meat|Body Composition|*Food Hypersensitivity|*Bacteria|*Intestine|*Mucosa 4373 tlr3 32655851 Ther Adv Endocrinol Metab 2020 PMC7331767 10.1177/2042018820930902 0 0 0 2959 *Insulin Resistance|*Obesity|*Adipose Tissue|CXCL11 protein, human|*Chemokine CXCL11|*Inflammation|CXCL9 protein, human|Chemokine CXCL9|*Biomarkers|*Gene Expression|Adipose Tissue, Subcutaneous|*Biochemical Phenomena 4373 tlr3 32651134 Biomed J 2020 10.1016/j.bj.2020.05.007 0 0 0 2959 Child|Humans|*Toll-Like Receptor|*Seizures|*Encephalitis|*Drug Resistant Epilepsy|Toll-Like Receptor 7|Signal Transduction|Epileptic Syndromes|Infections 4373 tlr3 32650582 Microorganisms 2020 10.3390/microorganisms8071017 0 0 0 2959 Humans|*Diabetes Mellitus, Type 1|*Coxsackie B Virus|Enterovirus Infections|Enterovirus|Insulin-Secreting Cells|Insulin|Autoimmunity|*Virus|Pancreas|Genetic Susceptibility|*DNA Viruses|Immune Tolerance 4373 tlr3 32640052 Scand. J. Immunol. 2020 10.1111/sji.12930 0 0 0 2959 Humans|Adult|*Pancreaticoduodenectomy|*Pilot Projects|*Cytokines|TLR3 protein, human|Toll-Like Receptor 3|Toll-Like Receptor 7|Interleukin-12|Toll-Like Receptor 9|IL10 protein, human|IL10|Lymphocyte Activation|*Inflammation|*Pancreatectomy|C-Reactive Protein|*Postoperative Period|*Cohort Study 4373 tlr3 32640038 Alcohol. Clin. Exp. Res. 2020 10.1111/acer.14410 0 0 0 2959 Animals|Mice|*Mice, Inbred C57BL|Ethanol|Alcohol Drinking|Innate Immune Response|*Health Behavior 4373 tlr3 32631940 J. Neurosci. 2020 10.1523/JNEUROSCI.0666-20.2020 0 0 0 2959 Male|Animals|Mice|TLR3 protein, human|*Toll-Like Receptor 3|*Microglia|*Glioma|*Signal Transduction|Macrophages|Brain Neoplasms|Brain|Mice, Inbred C57BL 4373 tlr3 32629102 Fish Shellfish Immunol. 2020 10.1016/j.fsi.2020.06.050 0 0 0 2959 Animals|*Isavirus|*Orthomyxoviruses|Orthomyxoviridae Infections|*Transcriptome|Fish Diseases|Interferon Type I|Innate Immune Responses|Salmo salar|Cell Line|Aquiculture|Downregulation|Up-Regulation|Gene Expression Profiling|South Australia 4373 tlr3 32628310 Pediatr Allergy Immunol 2020 10.1111/pai.13317 0 0 0 2959 Humans|Infant|*Lymphocytes|*Respiratory Sounds|*Immunity, Innate|*Bronchiolitis|Cytokines|*Immune System Phenomena 4373 tlr3 32621945 Antiviral Res. 2020 10.1016/j.antiviral.2020.104854 0 0 0 2959 *Type I Interferon|*Up-Regulation|*Myeloid Differentiation Factor 88|*Antiviral Agents|Interferon-beta|*Adaptor Proteins, Signal Transducing|Venezuelan equine encephalitis virus|Poly I-C|*Transcriptional Activation|Signal Transduction|Virus Replication|Cell Line 4373 tlr3 32611725 J. Immunol. 2020 10.4049/jimmunol.2000407 0 0 0 2959 Humans|*Macrophages|*Signal Transduction|Complement, C5a|CMKLR1 protein, human|Receptors, Chemokine|*Leukocyte Count|Complement Activation 4373 tlr3 32604471 Addict Biol 2020 10.1111/adb.12932 0 0 0 2959 Male|Mice|Animals|TLR3 protein, human|*Toll-Like Receptor 3|*Ethanol|*Alcohol Consumption|*Drug Tolerance|Toll-Like Receptor 4|Myeloid Differentiation Factor 88|Hypnotics and Sedatives|Mice, Inbred C57BL|*Immune Tolerance 4373 tlr3 32600413 Vet. Res. 2020 PMC7322901 10.1186/s13567-020-00801-0 0 0 0 2959 Animals|Female|Male|*Newcastle disease virus|*Chickens|*Specific Pathogen-Free Organisms|*Testis|Disease, Newcastle|Poultry Diseases|Cytokines|Genotype|Viral Load|TLR3 Receptor|*Lipogenesis 4373 tlr3 32599245 Int. J. Biol. Macromol. 2020 PMC7319641 10.1016/j.ijbiomac.2020.06.228 0 0 0 2959 Humans|COVID-19|severe acute respiratory syndrome coronavirus 2|*Coronavirus|*Coronavirus Infections|Pneumonia, Viral|Pandemic|Betacoronavirus|SARS-CoV|*Innate Immune Response|Interferon|Antiviral Agents|*Gene Targeting 4373 tlr3 32595725 Evid Based Complement Alternat Med 2020 PMC7301251 10.1155/2020/2606402 0 0 0 2959 Rhizome|Medicine, Chinese Traditional|Curcuma|Drugs, Chinese Herbal|*Drug Delivery Systems 4373 tlr3 32593740 Mol. Cell. Endocrinol. 2020 PMC7315947 10.1016/j.mce.2020.110917 0 0 0 2959 Humans|*Coronavirus|COVID-19|severe acute respiratory syndrome coronavirus 2|*Coronavirus Infection|Pneumonia, Viral|Betacoronavirus|Pandemics|angiotensin converting enzyme 2|Peptidyl-Dipeptidase A|Receptors, Virus|Virus Replication|*Adipocytes 4373 tlr3 32591775 J. Infect. Dis. 2020 10.1093/infdis/jiaa364 0 0 0 2959 *Chikungunya Fever|DC-specific ICAM-3 grabbing nonintegrin|*Toll-Like Receptor 3|Nicaragua|*Lectins, C-Type|*Receptors, Cell Surface|*Cell Adhesion Molecules|Chikungunya virus|*Phenotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|TNF protein, human|*Tumor Necrosis Factor-alpha|Antibodies, Viral 4373 TM4SF1 32579929 Cell Rep 2020 10.1016/j.celrep.2020.107803 0 0 0 214 Humans|*Estrogens|RNA Polymerase II|Enhancer Elements, Genetic|*RNA|Promoter Regions, Genetic|Transcription, Genetic|Histone|Gene Expression Regulation|Estrogen Receptor alpha|Estradiol|MCF-7 Cells|TM4SF1 protein, human|Antigens, Surface|Neoplasm Proteins|EFEMP1 protein, human|Extracellular Matrix Proteins|KDM2A protein, human|F-Box Proteins 102 TM4SF1 32528897 Front Oncol 2020 PMC7256199 10.3389/fonc.2020.00836 0 0 0 214 102 TM4SF1 32376266 Life Sci. 2020 10.1016/j.lfs.2020.117746 0 0 0 214 *Keloid|*Proto-Oncogene Proteins c-akt|*Signal Transduction|RNA, Micro|Cell Proliferation|Cell Movement|Down-Regulation|Apoptosis|Cell Line, Tumor|Fibroblasts 102 TM4SF1 32149080 Biomed Res Int 2020 PMC7044477 10.1155/2020/1618527 0 0 0 214 Humans|Female|*Disease-Free Survival|Neoplasm Recurrence, Local|MIRN508 microRNA, human|miRNAs|*Carcinoma, Ovarian Epithelial|RNA, Long Noncoding|MIRN506 microRNA, human|Prognosis|*Ovarian Cancer|Gene Expression Regulation, Neoplastic|Messenger RNA|Biomarkers, Tumor|Gene Regulatory Networks|*Nucleotide Motifs|Kaplan-Meier Estimate|TM4SF1 protein, human|Antigens, Surface|Neoplasm Proteins 102 TM4SF1 32141552 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202002_20361 0 0 0 214 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Gene Expression Regulation, Neoplastic|MicroRNAs|Neoplasm Proteins|Cell Movement|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Antigens, Surface 102 TM4SF1 32066736 Transl Psychiatry 2020 PMC7026041 10.1038/s41398-020-0730-0 0 0 0 214 Adult|Humans|Child|Posttraumatic Stress Disorder|Stress, Psychological|Module, Gene|*Genomics|Gene Expression|Soldiers|Psychopathology|Monocytes|TM4SF1 protein, human|Antigens, Surface|Neoplasm Proteins|CMTM5 protein, human|Chemokines|Tumor Suppressor Proteins|MARVEL Domain-Containing Proteins|TUBB1 protein, human|Tubulin 102 TM4SF1 31983129 J BUON 2020 0 0 0 214 Male|Humans|*MAP Kinase Signaling System|*Prostate Cancer|*Signal Transduction|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Epithelial-Mesenchymal Transition|Neoplasm Proteins|Cell Line, Tumor|Antigens, Surface|MicroRNAs|Cadherins|*Neoplastic Processes|TM4SF1 protein, human 102 TM4SF1 31906774 Cancer Biol. Ther. 2020 10.1080/15384047.2019.1702401 1 0 0 214 102 TM4SF5 31956272 Exp. Mol. Med. 2020 PMC7000776 10.1038/s12276-019-0363-7 0 0 0 210 Proteomics|TSPAN32 protein, human|Tetraspanins|Membrane Proteins|ErbB Receptors|Signal Transduction|Epithelial-Mesenchymal Transition|Hepatocytes|Cell Movement|Integrins|Palmitoylation|Liver Diseases|*Transporters, Amino Acid|Cell Line, Tumor|Fibrosis 57 TM4SF5 31897180 Oncol Lett 2020 PMC6924189 10.3892/ol.2019.11134 0 0 0 210 Mice|Animals|Humans|*Cell Movement|Hepatocellular Carcinoma|TM4SF5 protein, human|Membrane Proteins|Liver Neoplasms|Cell Line, Tumor|*Pancreatic Cancer|Xenograft Model Antitumor Assays|Cell Proliferation|Colon Cancer|Antibodies, Monoclonal|Disease Models, Animal 57 TMC1 32493795 Sci Transl Med 2020 10.1126/scitranslmed.aay9101 0 0 0 66 Mice|Humans|Animals|*Hearing|Hair Cells, Auditory|Hair Cells, Vestibular|Deafness|*Disease Models, Animal|Hearing Loss, Sensorineural|Mutations|Membrane Proteins|Mechanotransduction, Cellular|Point Mutations|Allele|*Sensation 163 TMC1 32371604 J. Neurosci. 2020 PMC7275854 10.1523/JNEUROSCI.0163-20.2020 0 0 0 66 Animals|Stereocilia|Hair Cells, Auditory|Hair Cells, Auditory, Inner|Mechanotransduction, Cellular|Zebrafish|Membrane Proteins|Mutation 163 TMC1 32343945 Neuron 2020 PMC7351599 10.1016/j.neuron.2020.03.033 0 0 0 66 Animals|*Mechanotransduction, Cellular|*Hair Cells, Cochlear|Mutation|Membrane Proteins|*Mammals|Calcium|Animals, Newborn 163 TMC1 32325031 Neuron 2020 PMC7343241 10.1016/j.neuron.2020.03.026 0 0 0 66 Animals|*Mechanotransduction, Cellular|ANK2 protein, human|*Ankyrins|Caenorhabditis elegans|Mechanoreceptor|Touch|Transient Receptor Potential Channels|Hearing|*Cytoplasm|Touch Perception|Neurons|TMC-1 protein, C elegans|Ion Channels 163 TMC1 32225107 Int J Mol Sci 2020 PMC7177576 10.3390/ijms21072300 0 0 0 66 Humans|*Exon|*RNA Splicing|RNA Splice Sites|RNA Precursors|Introns|Alternative Splicing|Mutation|ATP-Binding Cassette Transporters 163 TMC1 32219816 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.04.003 0 0 0 66 Infant, Newborn|Humans|Connexins|Connexin 26|DNA Mutational Analysis|Sulfate Transporters|Deafness|Genetic Testing|RNA, Ribosomal|Neonatal Screening|DNA, Mitochondrial|Mutation|Asian Continental Ancestry Group|Membrane Transport Proteins|China 163 TMC1 32167554 Hum. Mol. Genet. 2020 10.1093/hmg/ddaa045 1 0 0 66 Humans|Mice|Animals|*Zebrafish|Mechanotransduction, Cellular|Hair Cells, Auditory|Stereocilia|*Hearing|Zebrafish Proteins|Hair Cells, Vestibular|TYRP1 protein, human|*Membrane Glycoproteins|Lateral Line System|*Hearing Tests|Hearing Loss, Sensorineural|Deafness|Membrane Proteins|Mutations|TMC1 protein, human|TMC1 protein, mouse 163 TMC1 32152768 J. Assoc. Res. Otolaryngol. 2020 PMC7270392 10.1007/s10162-020-00746-3 0 0 0 66 Mice|Animals|*Animals, Newborn|gentamicin B|*Gentamycin|Hair Cells, Auditory|Hair Cells, Auditory, Inner|Mechanotransduction, Cellular|Aminoglycosides|Membrane Proteins|Patch-Clamp Techniques|Anti-Bacterial Agents|Transient Receptor Potential Channels|Mutation|Piezo2 protein, mouse|Ion Channels 163 TMC1 32048492 Harefuah 2020 0 0 0 66 Humans|*Deafness|DFNA3 protein, human|Connexins|Connexin 26|*Hearing Loss, Sensorineural|Jews|Hearing Loss|Mutation|Israel 163 TMC1 32009898 Front Mol Neurosci 2020 PMC6974483 10.3389/fnmol.2019.00320 0 0 0 66 Mice|Animals|Mechanotransduction, Cellular|Hair Cells, Auditory|Stereocilia|Hair Cells, Auditory, Inner|Zebrafish|Membrane Proteins|Cadherins|Pcdh15 protein, mouse|Protein Precursors|PCDH15 protein, zebrafish|Zebrafish Proteins 163 TMC1 31902726 Curr. Biol. 2020 PMC7002276 10.1016/j.cub.2019.11.076 2 0 0 66 Mice|Animals|*Stereocilia|*Hair Cells, Auditory, Inner|*Mechanotransduction, Cellular|*Hair Cells, Vestibular|Hair Cells, Auditory|Cilia|Actin|Membrane Proteins 163 TMC2 32371604 J. Neurosci. 2020 PMC7275854 10.1523/JNEUROSCI.0163-20.2020 0 0 0 41 Animals|Stereocilia|Hair Cells, Auditory|Hair Cells, Auditory, Inner|Mechanotransduction, Cellular|Zebrafish|Membrane Proteins|Mutation 53 TMC2 32343945 Neuron 2020 PMC7351599 10.1016/j.neuron.2020.03.033 0 0 0 41 Animals|*Mechanotransduction, Cellular|*Hair Cells, Cochlear|Mutation|Membrane Proteins|*Mammals|Calcium|Animals, Newborn 53 TMC2 32152768 J. Assoc. Res. Otolaryngol. 2020 PMC7270392 10.1007/s10162-020-00746-3 0 0 0 41 Mice|Animals|*Animals, Newborn|gentamicin B|*Gentamycin|Hair Cells, Auditory|Hair Cells, Auditory, Inner|Mechanotransduction, Cellular|Aminoglycosides|Membrane Proteins|Patch-Clamp Techniques|Anti-Bacterial Agents|Transient Receptor Potential Channels|Mutation|Piezo2 protein, mouse|Ion Channels 53 TMC2 31902726 Curr. Biol. 2020 PMC7002276 10.1016/j.cub.2019.11.076 2 0 0 41 Mice|Animals|*Stereocilia|*Hair Cells, Auditory, Inner|*Mechanotransduction, Cellular|*Hair Cells, Vestibular|Hair Cells, Auditory|Cilia|Actin|Membrane Proteins 53 tmco1 32214227 Eur. J. Hum. Genet. 2020 10.1038/s41431-020-0609-9 0 0 0 185 Humans|*Arabs|*Exome|*Whole Exome Sequencing|Homozygote|DNA Mutational Analysis|Mutations|Pedigree|Polymorphism, Single Nucleotide|Inbreeding|Genetic Association Studies|*Disorders, Neurological|Cohort Studies|Israel|APTX protein, human|DNA-Binding Proteins|Nuclear Proteins|CNTNAP1 protein, human|Cell Adhesion Molecules, Neuronal 42 TMEM106B 32602777 RNA Biol 2020 10.1080/15476286.2020.1771519 0 0 0 173 *Coronary Artery Disease|*RNA, Long Noncoding|*RNA Splicing|Genetic Predisposition to Disease|Splicings, Alternative|Risk Factors|Endothelial Cells 100 TMEM106B 32595021 Brain Dev. 2020 10.1016/j.braindev.2020.06.002 0 0 0 173 Pelizaeus-Merzbacher Disease|Myelin Proteolipid Protein|*Mutation|*Databases, Genetic|Myelin 100 TMEM106B 32572497 Brain 2020 10.1093/brain/awaa154 0 0 0 173 Animals|Mice|*Risk Factors|*Frontotemporal Lobar Degeneration|*Frontotemporal Dementia|Lysosome|Membrane Proteins|Nerve Tissue Proteins|Cathepsin D|lysosomal proteins|Proteolipids|Exocytosis|Protein Transport|Myelin Sheath|Oligodendrocytes|Neurons|Mutation 100 TMEM106B 32526197 Neuron 2020 10.1016/j.neuron.2020.05.010 0 0 0 173 Humans|Aged|TDP-43 Proteinopathies|*Brain|*Aging|Frontotemporal Lobar Degeneration|Nerve Tissue Proteins|Membrane Proteins|Frontotemporal Dementia|Progranulins|Polymorphism, Single Nucleotide|DNA-Binding Proteins|Genotype|Haplotype|*Gene Expression|Lysosomes|TMEM106B protein, human|TDP-43 protein, human 100 TMEM106B 32515674 Autophagy 2020 10.1080/15548627.2020.1771858 0 0 0 173 Humans|Proteomics|*Lysosome|Autophagosomes|*Neurons|Autophagy|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Signal Transduction|Homeostasis|HeLa Cells|Calcium|*Biosensor|Hydrogen-Ion Concentration 100 TMEM106B 32504082 Brain 2020 PMC7296855 10.1093/brain/awaa141 0 0 0 173 Animals|Mice|*Frontotemporal Dementia|*Pick Disease of the Brain|Progranulin|Nerve Tissue Proteins|Intercellular Signaling Peptides and Proteins|Membrane Proteins|DNA-Binding Proteins|Brain|Lysosomes|Mutation|Polymorphism, Single Nucleotide|Neurodegenerative Diseases|Haplotypes 100 TMEM106B 32492070 PLoS Genet. 2020 PMC7295244 10.1371/journal.pgen.1008775 0 0 0 173 Humans|*Alzheimer Disease|*Transcriptome|*Modifier Gene|Genetic Predisposition to Disease|Genome-Wide Association Study|Brain|Endophenotypes|Case-Control Studies|Genetic Loci|Cohort Study|TMEM106B protein, human|Membrane Proteins|Nerve Tissue Proteins 100 TMEM106B 32237974 J Am Heart Assoc 2020 10.1161/JAHA.119.014146 0 0 0 173 Humans|*Genome-Wide Association Study|*Epistasis, Genetic|*Cardiovascular Diseases|*Risk Factors|*Genomics|Genetic Predisposition to Disease|Coronary Artery Disease|Polymorphism, Single Nucleotide|Gene Expression Regulation|RNA, Long Noncoding|Gene Expression Profiling|Phenotypes|*Cardiovascular System 100 TMEM106B 32160553 Cell Rep 2020 10.1016/j.celrep.2020.02.060 0 0 0 173 Animals|Mice|*Axon Initial Segment|*Risk Factors|*Frontotemporal Lobar Degeneration|*Frontotemporal Dementia|*Lysosomes|Progranulin|Membrane Protein|Nerve Tissue Proteins|Intercellular Signaling Peptides and Proteins|*Motoneurons|Heterozygote|Protein Transport|Polymorphism, Single Nucleotide|Lipofuscin|Mutation|Vacuoles 100 TMEM135 32515224 Exp. Biol. Med. (Maywood) 2020 10.1177/1535370220932856 0 0 0 40 Mice|Animals|Mitochondrial Dynamics|Mitochondria|*Mutation|*Biochemical Phenomena 20 TMEM135 32157776 EMBO Rep. 2020 PMC7202201 10.15252/embr.201948901 1 0 0 40 Animals|Centrioles|Cilia|*Cytoplasm|rab GTP-Binding Proteins|Protein Transport|Cytoplasmic Vesicles|Zebrafish|*Cholesterol|Protein Binding|Cell Line 20 TMEM163 32492420 Cell Rep 2020 PMC7337098 10.1016/j.celrep.2020.107704 0 0 0 9 Receptors, Purinergic P2X|Signal Transduction|Adenosine Triphosphate|Calcium 22 TMEM165 32599014 Biochim Biophys Acta Gen Subj 2020 10.1016/j.bbagen.2020.129674 0 0 0 47 Humans|*Glycosylation|*Manganese|*Trace Elements|*Congenital Disorders of Glycosylation|*Golgi Apparatus|*Homeostasis|Cytosol|Cation Transport Proteins|Secretory Pathway|Membrane Proteins|Ion Transport|HEK293 Cells|Mutation|TMEM165 protein, human 40 TMEM165 32335229 Biochimie 2020 10.1016/j.biochi.2020.04.017 0 0 0 47 Humans|*Pemphigus, Benign Familial|Calcium-Transporting ATPases|Congenital Disorders of Glycosylation|Golgi Apparatus|Membrane Proteins|HEK293 Cells|Glycosylation|Manganese|TMEM165 protein, human 40 TMEM165 32047108 J. Biol. Chem. 2020 PMC7086029 10.1074/jbc.RA119.012249 1 0 0 47 40 TMEM165 32003966 Anal. Chem. 2020 10.1021/acs.analchem.9b04709 0 0 0 47 Humans|*Photoacoustic Techniques|*Golgi Apparatus|Congenital Disorders of Glycosylation|Glycosylation|Membrane Proteins|Homeostasis|Manganese|Calcium|HeLa Cells|HEK293 Cells|Hydrogen-Ion Concentration|TMEM165 protein, human 40 TMEM18 32384785 Genes (Basel) 2020 10.3390/genes11050516 0 0 0 59 Humans|*Polymorphism, Single Nucleotide|*Roma|Ethnic Groups|Minority Groups|*Obesity|Waist Circumference|Body Mass Index|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Genetic Predisposition to Disease|Genetic Association Studies|Asian Continental Ancestry Group|Alleles|*Risk Factors|Genotype|Phenotypes|Hungary|Europe 135 TMEM18 32228543 BMC Med. Genet. 2020 PMC7106578 10.1186/s12881-020-00999-y 0 0 0 59 Humans|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|*Asian Continental Ancestry Group|*Obesity|Body Mass Index|Receptor, Melanocortin, Type 4|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Membrane Proteins|Apoptosis Regulatory Proteins|Risk Factors|FAIM2 protein, human|CDKAL1 protein, human|tRNA Methyltransferases|TMEM18 protein, human 135 TMEM18 32147644 J Epidemiol 2020 10.2188/jea.JE20190296 0 0 0 59 Humans|*Body Mass Index|Genome-Wide Association Study|Japan|*Cohort Studies|Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Receptor, Melanocortin, Type 4|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Ethnicity|Genotype|Membrane Proteins|Diabetes Mellitus, Type 2 135 TMEM18 32109558 Gene 2020 10.1016/j.gene.2020.144509 0 0 0 59 Humans|Genome-Wide Association Study|Diabetes Mellitus, Type 2|*Arabs|United Arab Emirates|*Overweight|*Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Genetic Predisposition|Body Mass Index|Receptor, Melanocortin, Type 4|Polymorphism, Single Nucleotide|Membrane Proteins|Genotype|DNA-Binding Proteins 135 TMEM18 32069471 Lifestyle Genom 2020 10.1159/000505749 0 0 0 59 Child|Adult|Humans|Genome-Wide Association Study|*Social Determinants of Health|*Lifestyle|Obesity|Body Mass Index|Overweight|Body Weight|Adiposity|Single Nucleotide Polymorphisms|Risk Factors 135 TMEM38B 32392781 Cancers (Basel) 2020 PMC7281002 10.3390/cancers12051182 0 0 0 37 Humans|*Carcinoma, Renal Cell|*mRNA|Prospective Studies|Neoplasm Recurrence, Local|Kidney Neoplasms|Ubiquitin Thiolesterase|Tumor Suppressor Proteins|Nuclear Proteins|Prognosis|Histone Demethylases|Histone-Lysine N-Methyltransferase|Transcription Factors|Mutation|Cohort Studies 25 TMEM38B 32123938 Osteoporos Int 2020 10.1007/s00198-020-05366-4 0 0 0 37 *Osteogenesis Imperfecta|Type I Collagen|Phenotype|Mutation|Genotype|*Cohort Studies|Brazil 25 TMEM70 32275929 Biochim Biophys Acta Bioenerg 2020 10.1016/j.bbabio.2020.148202 1 0 0 63 Humans|*Electron Transport Complex I|Oxidative Phosphorylation Deficiencies|Oxidative Phosphorylation|Mitochondrial Proteins|Mitochondrial Proton-Translocating ATPases|Mitochondria|Mutations|Membrane Proteins|Fibroblasts|TMEM70 protein, human 44 TNFAIP2 32560248 Animals (Basel) 2020 10.3390/ani10061040 0 0 0 118 Animals|*Goats|*DNA Copy Number Variations|Breeding|Genome|Genotype|Genetics, Population|Polymorphism, Single Nucleotide|*Computational Biology|Genomics 64 TNFAIP2 32544907 Obes Facts 2020 10.1159/000507817 0 0 0 118 Humans|*Leukocytes, Mononuclear|*Transcriptome|*Obesity|Overweight|Body Mass Index|Leptin|Body Composition|Adipose Tissue 64 TNFAIP2 32501156 J. 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Blood Flow Metab. 2020 10.1177/0271678X20928147 0 0 0 118 64 TNFAIP2 32467880 Cancer Rep (Hoboken) 2020 PMC7254960 10.1002/cnr2.1213 0 0 0 118 Humans|*MCF-7 Cells|Cell Communication|*Nanotubes|*Macrophages|Epidermal Growth Factor|Biological Transport|*Neoplastic Processes|Actin Cytoskeleton 64 TNFAIP2 32456459 DNA Cell Biol. 2020 10.1089/dna.2020.5415 0 0 0 118 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Epigenesis, Genetic|Cisplatin|RNA, Micro|A549 Cells|Drug Resistance, Neoplasm|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Down-Regulation|*Genes, Regulator|Immunohistochemistry 64 TNFAIP2 32368089 Onco Targets Ther 2020 PMC7182456 10.2147/OTT.S241344 0 0 0 118 *Tumor Necrosis Factor-alpha|TYRP1 protein, human|*Membrane Glycoproteins|TNFAIP3 protein, human|Tumor Necrosis Factor alpha-Induced Protein 3|*Oxidoreductases|*Tumors|NF-kappa B|Signal Transduction|Apoptosis Regulatory Proteins|Intracellular Signaling Peptides and Proteins|DNA-Binding Proteins|Apoptosis 64 TNFAIP2 32234386 Toxicol. Appl. Pharmacol. 2020 10.1016/j.taap.2020.114977 0 0 0 118 Humans|Male|Animals|tri-o-cresyl phosphate|*MCF-7 Cells|Molecular Docking Simulation|Plastics|*Tritolyl Phosphates|*Receptors, Estrogen|Plasticizers|Autophagy|Cell Survival|microtubule-associated protein 1B|Microtubule-Associated Proteins|Estrogens|Cell Cycle|Oestradiol|Genes, cdc|Genes, Regulator|STC2 protein, human|Glycoproteins 64 TNFAIP6 32484571 Eur Cell Mater 2020 10.22203/eCM.v039a15 0 0 0 517 *Interleukin 1|*Intervertebral Disk|Anulus Fibrosus|Intervertebral Disc Degeneration|Nucleus Pulposus|TNF protein, human|Tumor Necrosis Factor alpha|Extracellular Matrix|Inflammation|IGF1 protein, human|Insulin-Like Growth Factor I|Signal Transduction|Gene Expression|Anti-Inflammatory Agents 400 TNFAIP6 32389179 Reprod. Fertil. Dev. 2020 10.1071/RD19310 0 0 0 517 Humans|Female|Mice|Animals|Horses|*Peroxiredoxin II|GDF9 protein, human|Growth Differentiation Factor 9|Bone Morphogenetic Protein 15|Cumulus Cells|Oocyte|Ovulation|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|*Oogenesis|EREG protein, human|Epiregulin|intraovarian peptides|Hyaluronan Synthase 2|Chorionic Gonadotropin|Gonadotropins, Equine|Gene Expression|Signal Transduction 400 TNFAIP6 32372097 Hum. Reprod. 2020 PMC7259369 10.1093/humrep/deaa077 0 0 0 517 Humans|Mice|Female|Animals|*Testosterone|*Metformin|*MAPK, p38|*Endoplasmic Reticulum Stress|*Granulosa Cells|Follicular Fluid|Polycystic Ovary Syndrome|Androgens 400 TNFAIP6 32368089 Onco Targets Ther 2020 PMC7182456 10.2147/OTT.S241344 0 0 0 517 *Tumor Necrosis Factor-alpha|TYRP1 protein, human|*Membrane Glycoproteins|TNFAIP3 protein, human|Tumor Necrosis Factor alpha-Induced Protein 3|*Oxidoreductases|*Tumors|NF-kappa B|Signal Transduction|Apoptosis Regulatory Proteins|Intracellular Signaling Peptides and Proteins|DNA-Binding Proteins|Apoptosis 400 TNFAIP6 32298610 J. Comput. Biol. 2020 10.1089/cmb.2019.0492 0 0 0 517 Gene Modules|Gene Expression Profiling|*Biomarkers|Gene Ontology|Profile, Gene Expression|Bioinformatics|*Sclerosis, Systemic|Receiver Operating Characteristic|*Hypertension, Pulmonary 400 TNFAIP6 32228439 BMC Genomics 2020 PMC7106838 10.1186/s12864-020-6671-4 0 0 0 517 Female|Animals|*MicroRNAs|*mRNA|*Goats|*Ovarian Follicles|*Estrus|Ovary|Gene Expression Profiling|Sequencing, RNA|Base Sequence|Signal Transduction|Hair Follicle 400 TNFAIP6 32157304 J. Infect. Dis. 2020 PMC7336574 10.1093/infdis/jiaa109 0 0 0 517 Humans|*Coinfection|*Hepacivirus|Antiviral Agents|Hepatitis C, Chronic|*Hepatitis C|*HIV Infections|*Inflammation|HIV|*Cognition 400 TNFAIP6 32138539 Syst Biol Reprod Med 2020 10.1080/19396368.2020.1725685 0 0 0 517 Female|Humans|*Cumulus Cells|*Versicans|*Oocyte|*Oogenesis|Bone Morphogenetic Protein 15|Embryonic Development|Gene Expression|RNA, Messenger 400 TNFAIP6 32073752 Mol Genet Genomic Med 2020 PMC7196489 10.1002/mgg3.1133 1 0 0 517 Humans|*Bloom Syndrome|*Transcriptome|Sister Chromatid Exchanges|DNA Repair|*Microarray Analysis|Telangiectasis|Mutations|Immunologic Deficiency Syndromes|Brazil 400 TNFAIP6 32046393 Reprod Sci 2020 10.1007/s43032-019-00004-9 0 0 0 517 Female|Swine|Animals|*Cumulus Cells|trisialoganglioside GT1|*MAP Kinase Signaling System|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|EGFR protein, human|*Epidermal Growth Factor Receptor|*Oogenesis|Oocytes|*Signal Transduction|*Gangliosides|In Vitro Oocyte Maturation Techniques|Epidermal Growth Factor|Blastocyst|*Cell Proliferation 400 TNFAIP6 32040478 PLoS ONE 2020 PMC7010233 10.1371/journal.pone.0220756 0 0 0 517 Male|Dogs|Mice|Animals|*Mice, Inbred C57BL|*Colitis|Dextran Sulfate|*Extracellular Vesicles|Mesenchymal Stem Cell Transplantation|Colon|Cytokines|Mesenchymal Stem Cells|IL10 protein, human|IL10|Macrophage Activation|Macrophages|Adipose Tissue|T-Cells, Regulatory|Tumor Necrosis Factor-alpha|Inflammation|Disease Models, Animal 400 TNFAIP6 31969876 Front Immunol 2020 PMC6960179 10.3389/fimmu.2019.02874 0 0 0 517 400 TNP1 32568099 Aging (Albany NY) 2020 PMC7343452 10.18632/aging.103205 0 0 0 248 Humans|Male|Sperm Motility|*Spermatogenesis|Spermatozoa|Testis|Sperm Count|Germ Cells|Busulphan|*Polysaccharides 93 TNP1 32319195 Clin Implant Dent Relat Res 2020 10.1111/cid.12911 0 0 0 248 *RNA, Long Noncoding|*Peri-Implantitis|miRNAs|*High-Throughput Nucleotide Sequencing|Gene Regulatory Networks|RNA, Messenger|*Periodontitis 93 TNP1 32247832 Clin. Immunol. 2020 10.1016/j.clim.2020.108405 0 0 0 248 *Arthritis, Psoriatic|*Immunity, Innate|Psoriasis|IL23R protein, human|Receptors, Interleukin|Adaptive Immunity|Genome-Wide Association Study|Genetic Predisposition to Disease|HLA-C|Skin|IL17A protein, human|IL-17|Nails|Immune System 93 TNP1 32227709 Zhonghua Nan Ke Xue 2020 0 0 0 248 Humans|Male|Mice|Animals|*Testis|*BALB C Mice|*Spermatogenesis|Sertoli Cell-Only Syndrome|Seminiferous Tubules|Spermatozoa|Meiosis|Adaptor Proteins, Signal Transducing|Apoptosis 93 TNP1 31932482 Mol. Cell. Biol. 2020 PMC7076252 10.1128/MCB.00228-19 0 0 0 248 Male|Female|Mice|Animals|*Transcription Factor|*Spermiogenesis|Transcription Factor TFIID|TATA-Binding Protein Associated Factors|Testis|Ovary|*Gene Expression Regulation 93 TNP2 32607133 Mob DNA 2020 PMC7320549 10.1186/s13100-020-00219-7 0 0 0 42 *DNA, Satellite|Transposable Elements|Phylogeny|Sequence Analysis, DNA|Computational Biology 118 TNP2 32141651 Andrologia 2020 10.1111/and.13554 0 0 0 42 Male|Mice|Animals|lycium barbarum polysaccharide|*Ethanol|*Testis|*Drugs, Chinese Herbal|Spermatogenesis|Lycium|*Protective Agents|Spermatozoa|Oxidative Stress|Antioxidants|Apoptosis 118 TNP2 31932482 Mol. Cell. Biol. 2020 PMC7076252 10.1128/MCB.00228-19 0 0 0 42 Male|Female|Mice|Animals|*Transcription Factor|*Spermiogenesis|Transcription Factor TFIID|TATA-Binding Protein Associated Factors|Testis|Ovary|*Gene Expression Regulation 118 TNPO3 32581109 J. Virol. 2020 10.1128/JVI.00640-20 0 0 0 229 *Rous sarcoma virus|*Transportin|*gag Protein|Transport, Nucleo-cytoplasmic|Nuclear Localization Signals|*Cell Nucleus|beta Karyopherins|Virus Assembly|Nucleocapsid|RNA, Viral|Protein Transport|Retroviridae|HIV-1 81 TNPO3 32545337 Viruses 2020 10.3390/v12060636 0 0 0 229 *Reverse Transcription|*HIV-1|Proteomics|Virus Uncoating|Cyclophilin A|Capsid|Capsid Proteins|Host-Pathogen Interactions|HIV Infections|*HIV Seropositivity|Protein Binding 81 TNPO3 32234784 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7165476 10.1073/pnas.1918944117 0 0 0 229 *Nuclear Localization Signals|*Active Transport, Cell Nucleus|KPNB1 protein, human|beta Karyopherins|Importins|Cell Nucleus|Cytoplasm|Protein Binding|RNA-Binding Proteins 81 TNPO3 32188628 J. Clin. Pathol. 2020 10.1136/jclinpath-2020-206461 0 0 0 229 *Transcriptome|Epstein Barr Virus Infection|Herpesvirus 4, Human|*Lymphoma, T-Cell, Peripheral|Mutation 81 TNPO3 31980060 J. Invest. 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Genet. 2020 10.1093/hmg/ddaa098 0 0 0 17 Genome-Wide Association Study|*Blood Pressure|*Regulatory Regions|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Chromatin|Phenotype|Genetic Variation|*Blood Pressure Determination 27 ULK4 32401642 Autophagy 2020 10.1080/15548627.2020.1752548 0 0 0 17 Female|Pregnancy|Humans|*Autophagy|Apoptosis Regulatory Proteins|Endoplasmic Reticulum Stress|Signal Transduction|Apoptosis|*Cancer|*Endometrium 27 UPK1A 32665998 Investig Clin Urol 2020 PMC7329636 10.4111/icu.2020.61.4.411 0 0 0 118 Humans|Male|kallikrein-related peptidase 3, human|*Prostate-Specific Antigen|*Prostatic Hyperplasia|*mRNA|*Prostate Cancer|Kallikreins|Prostate|Biomarkers, Tumor|*Urinary Tract|Diagnosis, Differential|*Polymerase Chain Reaction 66 UPK1A 32614890 PLoS ONE 2020 10.1371/journal.pone.0229193 0 0 0 118 STMN1 protein, human|*Stathmin|*Urinary Bladder Neoplasms|*RNA|*Cell Proliferation|Gene Expression Regulation, Neoplastic|*Bladder|Microtubule Proteins|RNA, Messenger|Cell Transformation, Neoplastic 66 UPK1A 32368305 J Cancer 2020 PMC7196272 10.7150/jca.38830 0 0 0 118 66 UPK1A 32368143 Cancer Manag Res 2020 PMC7186006 10.2147/CMAR.S239418 0 0 0 118 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Cell Proliferation|Long Non-Coding RNA|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Movement|Cell Line, Tumor|Disease Progression 66 UPK2 32339497 Am. 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Genet. 2020 10.1093/hmg/ddaa131 0 0 0 181 Humans|Female|X Chromosome Inactivation|*Lupus Erythematosus, Systemic|*Lymphocytes|DNA Methylation|Genes, X-Linked|Chromosomes, Human, X|*Alleles|RNA, Long Noncoding|T-Lymphocytes 1489 XIST 32581553 Onco Targets Ther 2020 PMC7276200 10.2147/OTT.S238808 0 0 0 181 Humans|*RNA, Long Noncoding|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Proliferation|A549 Cells|Cell Movement|Cell Line, Tumor|Apoptosis|Cell Transformation, Neoplastic|PAX6 protein, human|PAX6 Transcription Factor|MIRN142 microRNA, human 1489 XIST 32575101 Cytogenet. Genome Res. 2020 10.1159/000508610 0 0 0 181 Humans|Male|Female|Mice|Animals|*X Chromosome Inactivation|*Pluripotent Stem Cells|*Embryonic Development|X Chromosome|Gene Dosage Compensation|Blastocyst|X-Linked Gene|Gene Expression Regulation, Developmental|RNA, Long Noncoding 1489 XIST 32572232 Nat. 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Microbiol. 2020 10.1146/annurev-micro-020620-062812 0 0 0 0 Humans|*Bacterial Protein|Ribonucleoproteins|RNA, Small Cytoplasmic|Noncoding RNA|Autoantigens|RNA, Bacterial|Nucleic Acid Conformation|Deinococcus 117 Y_RNA 32609822 Nucleic Acids Res. 2020 10.1093/nar/gkaa526 0 0 0 0 Humans|*RNase|*tRNA|*Endoribonucleases|*Ribonuclease, Pancreatic|RNA|Base Sequence|Nucleic Acid Conformation|Sequencing, RNA|Northern Blots 117 Y_RNA 32498257 Cancers (Basel) 2020 10.3390/cancers12061445 0 0 0 0 *Extracellular Vesicles|*Non-Coding RNA|miRNA|Exosomes|mRNA|piRNA|tRNA|Cell Communication|lncRNA 117 Y_RNA 32469055 Nucleic Acids Res. 2020 PMC7337961 10.1093/nar/gkaa414 0 0 0 0 Humans|Mice|Animals|*Autoantigens|Ribonucleoproteins|RNA, Small Cytoplasmic|RNA, Untranslated|RNA, Bacterial|Nucleic Acid Conformation|Autoantibodies|Lupus Erythematosus, Systemic|RNA Degradation|Exoribonucleases|DNA Replication 117 Y_RNA 32423154 Cancers (Basel) 2020 PMC7281143 10.3390/cancers12051238 0 0 0 0 Humans|*Cancers|Extracellular Vesicles|Ribonucleoproteins|Biomarkers, Tumor|Nucleic Acid Conformation|DNA Replication|RNA 117 Y_RNA 32285422 Adv. 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Biol. 2020 PMC7363058 10.1007/978-981-15-1671-9_20 0 0 0 0 Small Non-Coding RNA|*Cardiovascular System 117 YBEY 32605982 mBio 2020 PMC7327168 10.1128/mBio.00659-20 0 0 0 103 *Pseudomonas aeruginosa|*Virulence|*Endoribonucleases|Gene Expression Regulation, Bacterial|RNA, Bacterial|Escherichia coli Proteins|Bacterial Proteins|Ribosomes|Metalloproteins|RNA, Ribosomal, 16S|RNase 37 YBEY 32182356 Nucleic Acids Res. 2020 10.1093/nar/gkaa148 0 0 0 103 Humans|*Mitochondrial Ribosomes|RNA, Ribosomal, 16S|Ribosome|RNA, ribosomal, 12S|RNA, Ribosomal|Escherichia coli Proteins|RNA, Bacterial|Escherichia coli|Metalloproteins|Gene Expression Regulation, Bacterial|Mitochondria|Endoribonucleases|YbeY protein, E coli 37 YBX2 32393046 Int J Environ Health Res 2020 10.1080/09603123.2020.1757043 0 0 0 47 Humans|*MicroRNAs|Signal Transduction 92 YBX2 32365184 Nucleic Acids Res. 2020 PMC7261171 10.1093/nar/gkaa211 0 0 0 47 Animals|*Parasites|*RNA|*Leishmania|Protein-Arginine N-Methyltransferases|Histones|DNA Methylation|Protein Processing, Post-Translational|*Protein Stability|Arginine|Gene Expression Regulation|Gene Expression|Cytoplasm 92 YBX2 32086523 Nucleic Acids Res. 2020 PMC7144910 10.1093/nar/gkaa101 0 0 0 47 Female|Mice|Animals|*Transcription Factor|*Oogenesis|Oocyte|*Cell Differentiation|LIM-Homeodomain Proteins|Ovarian Follicle|Meiosis|Germ Cells|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|*Cell Proliferation|Gene Expression Regulation, Developmental|Ovaries|Figla protein, mouse|Ybx2 protein, mouse|RNA-Binding Proteins 92 YBX2 32021278 Onco Targets Ther 2020 PMC6968804 10.2147/OTT.S226770 1 0 0 47 Humans|*Transcriptome Analysis|Gene Regulatory Networks|Gene Ontology|Gene Expression Regulation, Neoplastic|Transcriptome|Computational Biology|Signal Transduction 92 YBX2 32020607 J. 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Immunol. 2020 PMC7100912 10.1038/s41590-020-0622-8 0 0 0 498 Humans|Lymphocyte Activation|NF-kappa B|Cytokines|Immunologic Memory|*Phenotype|Transcription Factors 20 ZC3H13 32631107 Bioengineered 2020 10.1080/21655979.2020.1787764 0 0 0 158 Carcinoma, Hepatocellular|Liver Neoplasms|Gene Expression Regulation, Neoplastic|Prognosis|Gene Expression Profiling|Methylation|Adenosine 22 ZC3H13 32566570 Ann Transl Med 2020 PMC7290648 10.21037/atm-20-2894 0 0 0 158 *Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|N(6)-methyladenosine|*Adenosine|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Methyltransferases|Cell Line, Tumor|Gene Expression Profiling|Disease Progression 22 ZC3H13 32474328 Am J Otolaryngol 2020 10.1016/j.amjoto.2020.102547 0 0 0 158 Thyroid Cancer, Papillary|Carcinoma, Papillary|Thyroid Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|RNA, Messenger 22 ZC3H13 32422573 Transl Oncol 2020 PMC7229291 10.1016/j.tranon.2020.100778 0 0 0 158 Humans|*Anus Neoplasms|*Carcinoma, Squamous Cell|Chemoradiotherapy|*Mutations|Papillomaviridae|Prognosis|Disease-Free Survival|Whole Exome Sequencing 22 ZC3H13 32419773 Cancer Cell Int. 2020 PMC7206820 10.1186/s12935-020-01238-3 0 0 0 158 Clear Cell Renal Cell Carcinoma|Kidney Neoplasms|Prognosis|Gene Expression Profiling|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Transcriptome|Databases, Genetic|ROC Curve|Kaplan-Meier Estimate 22 ZC3H13 32398949 Int. 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Sci. 2020 10.1007/s10620-020-06260-z 0 0 0 158 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Prognosis|N(6)-methyladenosine|Adenosine|RNA, Messenger|Methyltransferases|Biomarkers 22 ZC3H14 32589834 ACS Chem Neurosci 2020 10.1021/acschemneuro.0c00214 0 0 0 116 Humans|Animals|Mice|*tau Proteins|*Poly A|*Tauopathy|Neurofibrillary Tangles|Alzheimer Disease|Caenorhabditis elegans|*Inhibition, Psychological|*Mammals|Carrier Proteins|*Biophysical Phenomena|RNA|ZC3H14 protein, human|Nuclear Proteins|RNA-Binding Proteins 23 ZFAT 32574725 Neurobiol. Dis. 2020 10.1016/j.nbd.2020.104972 0 0 0 28 Humans|Aged|*Pedigree|*Longevity|Phenotype|*Genomics|Exome|Sequence Analysis, DNA|Genetic Variation|Utah 70 ZFAT 32458046 Eur J Trauma Emerg Surg 2020 10.1007/s00068-020-01386-1 2 0 0 28 *Expert Testimony|Femoral Fractures|Injury Severity Score|*Surgeries, Orthopedic|*Survey 70 ZFAT 32271776 PLoS ONE 2020 PMC7144971 10.1371/journal.pone.0230899 1 0 0 28 Humans|Male|Horses|Animals|DNA Copy Number Variations|*Genome|Breeding|Phenotypes|Genotype|INDEL Mutation|Single Nucleotide Polymorphisms|Body Size|ZFAT protein, human|Transcription Factors 70 ZFAT 32091312 Anim. Biotechnol. 2020 10.1080/10495398.2020.1728288 0 0 0 28 Horses|Animals|*Polymorphism, Single Nucleotide|Breeding|*Phenotype|Quantitative Trait Loci|Chromosome Mapping|HMGA2 Protein|Body Size|Allele|China 70 zfhx4 32473302 Ann. Oncol. 2020 10.1016/j.annonc.2020.05.019 0 0 0 66 Humans|Female|*Prognosis|*Transcriptome|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Biomarkers, Tumor|Disease-Free Survival|Gene Expression Regulation, Neoplastic 26 zfhx4 32105524 Genet Test Mol Biomarkers 2020 10.1089/gtmb.2019.0185 0 0 0 66 26 zfhx4 31896782 Leukemia 2020 PMC7266744 10.1038/s41375-019-0697-0 2 0 0 66 Adult|Humans|*Core Binding Factor|Cell Line, Tumor|DNA-Binding Proteins|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Leukemia, Myeloid, Acute|Core Binding Factor beta Subunit|Oncogene Proteins, Fusion|Translocation, Genetic|Mutations|Prognosis|ZBTB7A protein, human|Transcription Factors 26 ZFP36L2 32655569 Front Immunol 2020 PMC7324482 10.3389/fimmu.2020.01291 0 0 0 866 Humans|Mice|Animals|*T-Lymphocytes, Regulatory|ZFP36 protein, human|Tristetraprolin|*RNA Binding Protein|*Downregulation|Messenger RNA|Nuclear Proteins|3' Untranslated Region|HEK293 Cells|Amino Acid Sequence|Zfp36l1 protein, mouse 71 ZFP36L2 32545247 Cancers (Basel) 2020 PMC7352335 10.3390/cancers12061539 0 0 0 866 Humans|ZFP36 protein, human|*Tristetraprolin|*Cancer|*RNA-Binding Proteins|AU Rich Elements|mRNA|RNA Stability|3' Untranslated Regions|Gene Expression Regulation|Cell Line|Cellular Proliferation 71 ZFX 32577991 Mol. Biol. Rep. 2020 10.1007/s11033-020-05544-x 0 0 0 224 Animals|*Chiroptera|*Genotype|*Microsatellites|Genetics, Population|Genetic Variation|Alleles|High-Throughput Nucleotide Sequencing|Polymorphism, Genetic|Habitat|Australia|Western Australia 307 ZFX 32509876 Biomed Res Int 2020 PMC7254085 10.1155/2020/9549765 0 0 0 224 Animals|*RNA Interference|Y Chromosome|Zinc Finger|Kruppel-Like Transcription Factors|Deer 307 ZFX 32469048 Hum. Mol. Genet. 2020 10.1093/hmg/ddaa101 0 0 0 224 Humans|Male|Mice|Animals|Azoospermia, Nonobstructive|*Azoospermia|*Whole Exome Sequencing|*Oligospermia|*Chinese|*Cohort Studies|Genetic Predisposition to Disease|Infertility, Male|Polymorphism, Single Nucleotide|Spermatogenesis|CHD5 protein, human|DNA Helicases|Nerve Tissue Proteins|MCM9 protein, human|Minichromosome Maintenance Proteins|Mcm9 protein, mouse 307 ZFX 32406922 Nucleic Acids Res. 2020 PMC7293018 10.1093/nar/gkaa384 0 0 0 224 Female|Humans|*Transcription Factors|*CpG Islands|HEK293 Cells|Zinc Fingers|Y Chromosome|X Chromosome|*Promoter Regions, Genetic|Kruppel-Like Transcription Factors|Transcription, Genetic|Amino Acid Sequence|Cloning, Molecular|Gene Expression Regulation 307 ZFX 32257743 3 Biotech 2020 PMC7109247 10.1007/s13205-020-02179-4 0 0 0 224 *Cell Survival|*Pancreatic Cancer|Apoptosis|indole|*Indoles|*Downregulation|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Gene Expression Regulation, Neoplastic 307 ZFX 32190219 Gastroenterol Hepatol Bed Bench 2020 PMC7069543 0 0 0 224 *Stomach Neoplasms|*Zinc Finger|*Downregulation|Kruppel-Like Transcription Factors|Fibrinogen 307 ZFX 32021248 Onco Targets Ther 2020 PMC6942532 10.2147/OTT.S220998 2 0 0 224 *RNA, Long Noncoding|*Stomach Neoplasms|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Cell Proliferation|Cell Line, Tumor|Disease Progression|Signal Transduction|Cell Transformation, Neoplastic|Stomach 307 ZFX 31966320 Zool Stud 2020 PMC6838184 10.6620/ZS.2019.58-19 0 0 0 224 Male|Female|Animals|*DNA Primers|*Mammals|Sex Determination Analysis|Polymerase Chain Reaction|Base Sequence|Sequence Analysis, DNA|Conservation of Natural Resources 307 ZFX 31940807 Genes (Basel) 2020 PMC7017058 10.3390/genes11010085 0 0 0 224 Swine|Animals|*DNA, Ancient|*Sus scrofa|Breeding|Meat|Italy|Polymorphism, Single Nucleotide 307 ZHX2 32164487 Epigenetics 2020 10.1080/15592294.2020.1741757 0 0 0 190 Humans|*Papillomavirus Infections|*Alternative Splicing|*Oropharyngeal Neoplasms|*Human Papilloma Virus|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Cancer|Carcinoma, Squamous Cell|*Mouth Neoplasms|Cell Line, Tumor|Case-Control Studies|Chromatin|Humans|*Papillomavirus Infections|*Alternative Splicing|*Oropharyngeal Neoplasms|*Human Papilloma Virus|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Cancer|Carcinoma, Squamous Cell|*Mouth Neoplasms|Cell Line, Tumor|Case-Control Studies|Chromatin 78 ZHX2 32382017 Cell Death Dis 2020 PMC7206010 10.1038/s41419-020-2541-x 0 0 0 190 Humans|*Carcinoma, Renal Cell|*Sunitinib|*MAP Kinase Signaling System|Kidney Neoplasms|Von Hippel-Lindau Tumor Suppressor Protein|*Cell Proliferation|Oncogenes|Gene Expression Regulation, Neoplastic|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Immunohistochemistry|Biomarkers, Tumor|Cell Line, Tumor|Vascular Endothelial Growth Factor A|*Cell Cycle|*Autophagy|ZHX2 protein, human|Transcription Factors 78 ZHX2 32179636 J. Immunol. 2020 10.4049/jimmunol.1901246 0 0 0 190 Mice|Animals|*Glycolysis|*Macrophage|Phosphofructokinase-2|*Sepsis|Inflammation|Multiple Organ Failure|Cytokines|Disease Models, Animal|*Phosphoric Monoester Hydrolases|Zhx2 protein, mouse|Homeodomain Proteins 78 ZHX2 32125369 Genome Biol Evol 2020 PMC7144352 10.1093/gbe/evaa039 0 0 0 190 Mice|Animals|*Genes, Homeobox|*Chordate|*Zinc Finger|Proteins, Homeo Domain|Transcription Factors|Repressor Proteins|Amino Acid Sequence|Sequence Homology, Amino Acid|Gene Expression Regulation|*Biological Evolution 78 ZHX2 32114388 EBioMedicine 2020 PMC7047184 10.1016/j.ebiom.2020.102676 0 0 0 190 *Carcinoma, Hepatocellular|*Liver Cancer|Neoplasm Recurrence, Local|Homeodomain Proteins|Transcription Factors|Cell Line, Tumor|Neoplastic Stem Cells|Liver|Gene Knockdown Techniques|Zinc Fingers|*Demethylation 78 ZHX2 32103060 Sci Rep 2020 PMC7044248 10.1038/s41598-020-60401-y 0 0 0 190 Animals|Humans|*Fishes|Microsatellites|*Genetic Testing|Endangered Species|Alleles|*Reactions, Polymerase Chain|*Chinese|China 78 ZHX2 32059999 Kidney Int. 2020 10.1016/j.kint.2019.11.011 0 0 0 190 Humans|Rats|Mice|Animals|*Podocytes|*Genes, Homeobox|*Homeodomain Proteins|*Zinc Fingers|Transcription Factors|Repressor Proteins|Focal Segmental Glomerulosclerosis|Disease, Minimal Change|Proteinuria|Kidney Diseases|Amino Acid Sequence|ZHX2 protein, human|ZHX3 protein, human|Zhx2 protein, mouse 78 ZIC4 32450842 BMC Neurol 2020 PMC7249364 10.1186/s12883-020-01788-z 0 0 0 48 Humans|*Paraneoplastic Cerebellar Degeneration|Small Cell Lung Carcinoma|Lung Neoplasms|Nerve Tissue Proteins|Transcription Factors|Autoantibodies|ZIC4 protein, human 76 ZIC4 32087460 J. Neuroimmunol. 2020 10.1016/j.jneuroim.2020.577192 0 0 0 48 *Antibody Diversity|Stiff-Person Syndrome|Muscle Rigidity|Encephalomyelitis|Myoclonus|Receptors, Glycine|Glutamate Decarboxylase|Autoantibodies|amphiphysin|Nerve Tissue Proteins|Immunotherapy 76 ZMIZ1 32437091 Cell Biol. Int. 2020 10.1002/cbin.11396 0 0 0 162 Humans|*Proto-Oncogene Proteins c-akt|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|*Signal Transduction|F-Box Proteins|*Pancreatic Cancer|Cell Proliferation|Cell Cycle Proteins|Ubiquitin-Protein Ligases|ZMIZ1 protein, human|Transcription Factors|salt-inducible kinase-2, human|Proteolysis|Cell Cycle|Cell Line, Tumor|TORC2 65 ZMIZ1 32170005 J. Med. Genet. 2020 10.1136/jmedgenet-2019-106374 0 0 0 162 *Adenomatous Polyposis Coli|Colonic Polyps|Colonoscopy|Colorectal Cancer|Adenoma|*Syndrome|Colonic Neoplasms|Colon 65 ZMIZ1 31921621 Front Oncol 2020 PMC6915105 10.3389/fonc.2019.01328 0 0 0 162 Humans|*Triple-Negative Breast Cancer|*Prognosis|*Signal Transduction|Chemokine CCL5|Cell Line, Tumor|Kaplan-Meier Estimate|Case-Control Studies|Genetic Variation|CCL5 protein, human 65 ZNF185 32565799 J Oncol 2020 PMC7271247 10.1155/2020/3181596 0 0 0 64 *Drug Resistance, Neoplasm|*Pancreatic Cancer|SMAD4 protein, human|*Smad4 Protein|gemcitabine|Deoxycytidine|*Downregulation|*Upregulation|*Transcriptional Activation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic 24 ZNF365 32437414 PLoS ONE 2020 PMC7241744 10.1371/journal.pone.0233464 0 0 0 33 Humans|*Uveomeningoencephalitic Syndrome|beta-apocarotenoid-14',13'-dioxygenase|Genome-Wide Association Study|Japan|Oxygenases|IL23R protein, human|*Receptors, Interleukin|Carotenoids|Single Nucleotide Polymorphisms|Asian Continental Ancestry Group|Genetic Predisposition to Disease|Alleles|Gene Frequency|HLA-DR4|*Genes, Regulator|Genotype|Case-Control Studies|ZNF365 protein, human 57 ZNF469 32671420 Calcif. Tissue Int. 2020 10.1007/s00223-020-00721-3 0 0 0 19 Humans|Brittle cornea syndrome 1|*Joint Instability|*Whole Exome Sequencing|*Siblings|*Skin Abnormalities|*Eye Abnormalities|Ehlers-Danlos Syndrome|Osteogenesis Imperfecta|DNA-Binding Proteins|Transcription Factors|Phenotype|Mutations|Pedigree|Connective Tissue Diseases|ZNF469 protein, human 49 ZNF598 32657267 Elife 2020 10.7554/eLife.60038 0 0 0 133 Humans|*Ribosome|Protein Biosynthesis|mRNA|Ubiquitination|Ubiquitin|Carrier Proteins|*Protein Processing, Post-Translational|Ubiquitin-Protein Ligases|HEK293 Cells|*Proteomics|ZNF598 protein, human 20 ZNF598 32615089 Mol. Cell 2020 10.1016/j.molcel.2020.06.010 0 0 0 133 *Ribosome|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Protein Biosynthesis|Ubiquitin|Ubiquitination|mRNA|Ubiquitin-Protein Ligases|EIF-2|Phosphorylation|Hel2 protein, S cerevisiae 20 ZNF598 32586037 Biomolecules 2020 10.3390/biom10060951 0 0 0 133 Humans|Mice|Animals|*Ubiquitin|UBD protein, human|Ubiquitins|Proteasome Endopeptidase Complex|Ubiquitination|Proteolysis|HLA-F antigens|Histocompatibility Antigens Class I|Upregulation|Interferon-gamma|Tumor Necrosis Factor-alpha|Protein Binding|Downregulation|Signal Transduction Pathways|Protein Transport|ZNF598 protein, human|Carrier Proteins 20 ZNF598 32579943 Mol. Cell 2020 10.1016/j.molcel.2020.06.006 0 0 0 133 Humans|Animals|*Ribosomes|Ubiquitination|Ubiquitin|Protein Biosynthesis|Ribosomal Proteins|mRNA|40S Ribosomal Subunit|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Ubiquitin-Protein Ligases|Carrier Proteins|DNA Helicases|HEK293 Cells|Polysome|ZNF598 protein, human 20 ZNF598 32324387 Chem. Res. Toxicol. 2020 10.1021/acs.chemrestox.9b00412 0 0 0 133 Humans|arsenite|*Arsenites|*Ribosome|ribosomal protein S20|Ribosomal Proteins|Ubiquitination|Protein Biosynthesis|Ubiquitin|Carrier Proteins|RNA, Messenger|HEK293 Cells|Post-Translational Modifications|ZNF598 protein, human 20 ZNF598 32099016 Sci Rep 2020 PMC7042231 10.1038/s41598-020-60241-w 0 0 0 133 Humans|Animals|*Ribosome|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Ubiquitination|Protein Biosynthesis|Ubiquitin|Ubiquitin-Protein Ligases|RNA, Messenger|Binding Protein|*Quality Control|ZNF598 protein, human|TRIP4 protein, human|Transcription Factors|Hel2 protein, S cerevisiae 20 ZNF598 32011234 Elife 2020 PMC7064338 10.7554/eLife.54023 0 0 0 133 Humans|*Ribosomes|*Ubiquitylation|Ubiquitin|Ribosomal Proteins|Protein Biosynthesis|Saccharomyces cerevisiae Proteins|Ubiquitin-Protein Ligases|Saccharomyces cerevisiae|RNA, Messenger|Carrier Proteins|HEK293 Cells|USP21 protein, human|Ubiquitin Thiolesterase|ZNF598 protein, human|OTUD3 protein, human|Ubiquitin-Specific Proteases 20 ZNF598 31981475 Mol. Cell 2020 10.1016/j.molcel.2019.12.024 0 0 0 133 Humans|*RNA Recognition Motif Proteins|*DNA Helicases|*Poly-ADP-Ribose Binding Proteins|*RNA Helicases|*Ribosomes|*Ubiquitin|Protein Biosynthesis|Ubiquitination|Carrier Proteins|mRNA|RNA-Binding Proteins|HEK293 Cells|Protein Binding|E3 Ligase|*Lysosomes|Deubiquitinating Enzymes|USP10 protein, human|Ubiquitin Thiolesterase 20 ZNF644 32641122 BMC Med Genomics 2020 PMC7346436 10.1186/s12920-020-00745-6 0 0 0 140 Humans|CpG Islands|Epigenetic|DNA Methylation|Epigenesis, Genetic|Genome, Human|Promoter Regions, Genetic|Oligonucleotide Array Sequence Analysis|*Skin|Warts 20 ZNF644 32215939 Ophthalmic Physiol Opt 2020 10.1111/opo.12683 0 0 0 140 Humans|*Mutation|*Myopia|Exome|Pedigree|Genetic Predisposition to Disease|*Cohort Studies 20 ZNF804A 32663566 J Shoulder Elbow Surg 2020 10.1016/j.jse.2020.06.036 0 0 0 45 *Rotator Cuff|Rotator Cuff Injuries|Genetic Predisposition|*Genetics, Population|Polymorphism, Single Nucleotide|Case-Control Studies 172 ZNF804A 32626976 Mol Med Rep 2020 PMC7339789 10.3892/mmr.2020.11230 0 0 0 45 Humans|Schizophrenia|Studies, Genome-Wide Association|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Bipolar Disorder|Kruppel-Like Transcription Factors|Genotype|*Neuroblastoma|*Endopeptidases|ZNF804A protein, human|COMT protein, human|Catechol O-Methyltransferase 172 ZNF804A 32544854 Neuroimage Clin 2020 PMC7301231 10.1016/j.nicl.2020.102279 0 0 0 45 Genome-Wide Association Study|Prospective Studies|*Prefrontal Cortex|*Hippocampal Formation|Schizophrenia|fMRI|Brain Mapping|Neural Pathways|Polymorphism, Single Nucleotide|Genotype|Memory, Short-Term|Functional Laterality|Kruppel-Like Transcription Factors|Study, Genetic Association|Homozygotes|Neuropsychological Tests 172 ZNF804A 32329304 Clin Psychopharmacol Neurosci 2020 PMC7242106 10.9758/cpn.2020.18.2.231 0 0 0 45 Bipolar Disorder|Schizophrenia|Genetic Predisposition to Disease|Psychotic Disorders|Polymorphism, Single Nucleotide|Kruppel-Like Transcription Factors 172 ZNF804A 32059228 Neuropsychopharmacology 2020 PMC7297989 10.1038/s41386-020-0637-8 0 0 0 45 Humans|*Facial Expression|*Endophenotypes|*Temporal Lobe|*Schizophrenia|Emotions|Brain Mapping|fMRI|Pattern Recognition, Visual|Photic Stimulation|Social Behavior|ZNF804A protein, human|Kruppel-Like Transcription Factors 172 ZNF804A 31994908 Arch. 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Res. 2019 10.1007/s11120-019-00658-1 0 0 0 0 *Flavodoxin|flavin semiquinone|Chlorobium phaeovibrioides|*Flavin-Adenine Dinucleotide|flavin mononucleotide semiquinone|Flavin Mononucleotide|Oxidation-Reduction|Electron Transport|*Sulfur|Ferredoxin|hydroquinone|Hydroquinones|Bacterial Proteins|Escherichia coli|Thermodynamics 429 1.2.7.1 31276306 FEBS J. 2019 10.1111/febs.14981 0 0 0 0 Ferredoxin Oxidoreductase, Pyruvate|Ketone Oxidoreductases|Desulfovibrio|Amino Acid Sequence|Bacterial Proteins|Pyruvic Acid|Kinetics 429 1.2.7.1 31095609 PLoS ONE 2019 PMC6522037 10.1371/journal.pone.0217006 0 1 0 0 *Shock, Cardiogenic|*Hypoalbuminemia|Intra-Aortic Balloon Pumping|*Biomarkers|Myocardial Infarction|Hospital Mortality|Risk Factors|Intensive Care Units|Treatment Outcome|Time Factors 429 1.2.7.1 30839239 Metab Syndr Relat Disord 2019 10.1089/met.2018.0115 1 0 0 0 429 1.2.7.1 30705889 World J Clin Cases 2019 PMC6354094 10.12998/wjcc.v7.i2.122 2 0 0 0 Humans|Case-Control Studies|*Rectal Cancer|Laparoscopy|Natural Orifice Endoscopic Surgery|Operative Time|Retrospective Studies|Postoperative Complications|Length of Stay|Efficacy, Clinical 429 1.2.7.1 32219005 J Basic Appl Zool 2019 PMC7091895 10.1186/s41936-019-0131-1 0 0 0 0 Humans|Swine|Animals|*Influenza, Human|*Influenza A Virus, H1N1 Subtype|*Case-Control Studies|*Interleukin-6|*Interleukin-8|Egypt|*Polymorphism, Genetic 429 1.2.7.1 31855665 Child Abuse Negl 2019 10.1016/j.chiabu.2019.104327 0 0 0 0 Child|Humans|Child Abuse|*Documentation|*Family|Medical History Taking|*Physical Examination|Referral and Consultation 429 1.2.7.1 31762090 Dig Endosc 2019 10.1111/den.13584 0 0 0 0 Humans|*Stomach Neoplasms|*Herpesvirus 4, Human|*Incidence|*Lymphatic Metastasis|Endoscopic Submucosal Dissection|Gastrectomy|Epstein-Barr Virus Infections|Gastric Mucosa|*Early Detection of Cancer|Adenocarcinoma|Neoplasm Invasiveness|Risk Factor|Retrospective Studies|Lymph Nodes 429 1.2.7.1 31761446 Nefrologia 2019 10.1016/j.nefro.2019.07.005 0 0 0 0 Humans|*Diabetic Nephropathies|Kidney|Diabetes Mellitus, Type 2|Proteinuria|Biopsy|*Nephrectomy|Risk Factors|Retrospective Studies 429 1.2.7.1 31716801 Zootaxa 2019 10.11646/zootaxa.4657.1.7 0 0 0 0 Male|Animals|*Rivers|*Cyprinidae|India|Lateral Line System|Holometabola|GenBank|Abdominal Cavity|Chest|Anus|Torso|Pharynx|Data Collection|Lower Extremity|Prostate 429 1.2.7.1 31688720 Sex Transm Dis 2019 PMC7132779 10.1097/OLQ.0000000000001085 0 0 0 0 Humans|Female|*Gonorrhea|*Incidence|*Sex Workers|*Trichomonas|*Prospective Studies|Baltimore|*Infection, Trichomonas|Sexually Transmitted Infections|Chlamydia Infections|Neisseria gonorrhoeae|Chlamydia trachomatis|Trichomonas Vaginitis|*Cohort Studies|Trichomonas vaginalis|Prevalence 429 1.2.7.1 31614740 Animals (Basel) 2019 PMC6826550 10.3390/ani9100791 1 0 0 0 Female|Swine|Animals|*Water|*Diet|Digestion|Animal Nutritional Physiological Phenomena|Animal Feed|Dietary Fiber|Dietary Supplements|Gastrointestinal Tract|Feces|Zea mays|Soybeans|Body Weight|Gain, Weight 429 1.2.7.1 31302833 Photosyn. Res. 2019 10.1007/s11120-019-00658-1 0 0 0 0 *Flavodoxin|flavin semiquinone|Chlorobium phaeovibrioides|*Flavin-Adenine Dinucleotide|flavin mononucleotide semiquinone|Flavin Mononucleotide|Oxidation-Reduction|Electron Transport|*Sulfur|Ferredoxin|hydroquinone|Hydroquinones|Bacterial Proteins|Escherichia coli|Thermodynamics 429 1.2.7.1 31276306 FEBS J. 2019 10.1111/febs.14981 0 0 0 0 Ferredoxin Oxidoreductase, Pyruvate|Ketone Oxidoreductases|Desulfovibrio|Amino Acid Sequence|Bacterial Proteins|Pyruvic Acid|Kinetics 429 1.2.7.1 31095609 PLoS ONE 2019 PMC6522037 10.1371/journal.pone.0217006 0 1 0 0 *Shock, Cardiogenic|*Hypoalbuminemia|Intra-Aortic Balloon Pumping|*Biomarkers|Myocardial Infarction|Hospital Mortality|Risk Factors|Intensive Care Units|Treatment Outcome|Time Factors 429 1.2.7.1 30839239 Metab Syndr Relat Disord 2019 10.1089/met.2018.0115 1 0 0 0 429 1.2.7.1 30705889 World J Clin Cases 2019 PMC6354094 10.12998/wjcc.v7.i2.122 2 0 0 0 Humans|Case-Control Studies|*Rectal Cancer|Laparoscopy|Natural Orifice Endoscopic Surgery|Operative Time|Retrospective Studies|Postoperative Complications|Length of Stay|Efficacy, Clinical 429 1.2.7.1 32219005 J Basic Appl Zool 2019 PMC7091895 10.1186/s41936-019-0131-1 0 0 0 0 Humans|Swine|Animals|*Influenza, Human|*Influenza A Virus, H1N1 Subtype|*Case-Control Studies|*Interleukin-6|*Interleukin-8|Egypt|*Polymorphism, Genetic 429 A2ML1 31850076 Front Genet 2019 PMC6901973 10.3389/fgene.2019.01230 1 0 0 58 Child|Humans|Genome-Wide Association Study|*Otitis Media|Microbiome|*Microbial Interactions|Bacteria|*Epistasis, Genetic 39 A2ML1 31057598 Front Genet 2019 PMC6477999 10.3389/fgene.2019.00333 0 0 0 58 Humans|*Noonan Syndrome|South Africa|DNA Mutational Analysis|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Mutations|Phenotype|Sequencing, Next-Generation|Mutation Frequencies|Dwarfism 39 A2ML1 31009165 Hum. Mutat. 2019 PMC6711784 10.1002/humu.23769 3 0 0 58 Child|Humans|*Otitis Media|Middle Ear|Exome|Pedigree|alpha-Macroglobulins|Heterozygote|Genetic Predisposition to Disease|Cochlea|Finland|A2ML1 protein, human 39 A2ML1 30954612 J Proteomics 2019 10.1016/j.jprot.2019.04.004 2 0 0 58 Animals|*Proteomics|*Takifugu|*Temperature|Proteome|*Cold|Stress, Physiological|*Liver|Fishes|Signal Transduction 39 A2ML1 30943749 Neoplasma 2019 10.4149/neo_2018_180907N679 1 0 0 58 Humans|*RNA, Long Noncoding|*Autoimmunity|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Cancer|*Physical Examination|*PCR 39 A4GALT 31628463 Hum. Mol. Genet. 2019 10.1093/hmg/ddz246 0 0 0 57 44 A4GALT 31374005 Medicine (Baltimore) 2019 PMC6709120 10.1097/MD.0000000000016361 1 0 0 57 44 A4GALT 31273262 Sci Rep 2019 PMC6609624 10.1038/s41598-019-46029-7 0 1 0 57 44 A4GALT 30597575 Transfusion 2019 10.1111/trf.15115 1 1 0 57 44 ABCF2 31758671 Mol Oncol 2019 PMC6998385 10.1002/1878-0261.12603 2 6 0 143 Mice|Animals|*Carcinoma, Hepatocellular|*miRNA|*Liver Neoplasms|Mice, Nude|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Cell Movement|Cell Line, Tumor|*Neoplastic Processes|Xenograft Model Antitumor Assays|Disease Progression|RNA, Circular 33 ABCF2 30672151 Cancer Med 2019 PMC6382717 10.1002/cam4.1964 6 6 0 143 Humans|Female|*Computational Biology|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|ATP-Binding Cassette Transporters|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|*Disease Progression|ATP Binding Cassette Transporter, Subfamily B|Neoplasm Proteins|Gene Expression Profiling|*Profiles, Genetic 33 ABHD11 31568657 Cancer Med 2019 PMC6853820 10.1002/cam4.2586 5 9 0 25 Humans|Female|*Carcinoma, Ovarian Epithelial|*RNA, Long Noncoding|RNA I|*Ovarian Cancer|*RNA, Bacterial|*Tumorigenesis|TIMP2 protein, human|*TIMP-2|Gene Expression Regulation, Neoplastic|*Cell Transformation, Neoplastic|MicroRNAs|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Movement|Phosphatidylinositol 3-Kinases|Cell Line, Tumor|Apoptosis|Signal Transduction 32 ABHD11 31409775 Cell Death Dis 2019 PMC6692390 10.1038/s41419-019-1850-4 7 4 0 25 Humans|*Thyroid Cancer, Papillary|*RNA, Long Noncoding|*RNA, Anti-Sense|MicroRNAs|*Disease Progression|Gene Expression Regulation, Neoplastic|Thyroid Neoplasms|Cell Proliferation|Proto-Oncogene Proteins c-akt|Cell Movement|Biomarkers, Tumor|Cell Line, Tumor|SLC1A5 protein, human|Minor Histocompatibility Antigens|Amino Acid Transport System ASC 32 ABHD11 31333792 J Cancer 2019 PMC6636289 10.7150/jca.32052 3 0 0 25 32 ABHD11 31248089 Int J Mol Sci 2019 PMC6628585 10.3390/ijms20122986 0 0 0 25 Humans|*Paclitaxel|*MCF-7 Cells|PAGE, 2D|*Mitochondria|Protein, Mitochondrial|Antineoplastic Agents, Phytogenic|Drug Resistance, Neoplasm|Proteomics|Cell Line, Tumor|TYRP1 protein, human|*Membrane Glycoproteins|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Cathepsin D|siRNA|ATAD3A protein, human|ATPases Associated with Diverse Cellular Activities|Membrane Proteins 32 ABHD11 30888556 J. 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Des. 2019 PMC6516084 10.1007/s10822-019-00197-w 1 0 0 25 Humans|*Proteome|Binding Sites|Software|Protein Binding|Ligands|Protein Conformation|Drug Discovery|Models, Molecular|Algorithms|Drug Design|Supervised Machine Learning 32 ABHD11 30657221 Cell Prolif. 2019 PMC6495520 10.1111/cpr.12569 8 15 0 25 Mice|Animals|*Thyroid Cancer, Papillary|*RNA, Long Noncoding|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Up-Regulation|*Signal Transduction|STAT3 protein, human|*STAT3 Transcription Factor|MicroRNAs|Gene Expression Regulation, Neoplastic|Thyroid Neoplasms|Cell Proliferation|Cell Movement|*Transcriptional Activation|Cell Line, Tumor|Biomarkers, Tumor|*Neoplastic Processes|Apoptosis 32 abhd2 31537814 Sci Rep 2019 PMC6753062 10.1038/s41598-019-49177-y 5 0 0 142 Male|Adult|Humans|glyceryl 2-arachidonate|*Endocannabinoids|*Testis|Semen Analysis|Arachidonic Acids|Glycerides|Receptors, Cannabinoid|Monoacylglycerol Lipases|fatty-acid amide hydrolase|Amidohydrolases|Sertoli Cells|Spermatogenesis|Diacylglycerol Lipase|Leydig Cells|Cannabinoids|Spermatozoa|ABHD2 protein, human|Hydrolases 30 abhd2 31525885 ACS Chem. Biol. 2019 PMC6878212 10.1021/acschembio.9b00640 1 0 0 142 Animals|Male|Mice|*Acrosome Reaction|Sperm|Progesterone|Hydrolases|Abhd2 protein, mouse 30 abhd2 31035455 Int J Mol Sci 2019 PMC6539702 10.3390/ijms20092071 1 7 0 142 Mice|Animals|*Retinoic Acid|*F9 Embryonal Carcinoma Cells|*Cell Differentiation|Carcinoma, Embryonal|Pluripotent Stem Cells|Gene Expression Regulation, Neoplastic|Extracellular Signal Regulated Kinases|Up-Regulation|MicroRNAs|Abhd2 protein, mouse|Hydrolases 30 abhd2 30861420 Atherosclerosis 2019 10.1016/j.atherosclerosis.2019.02.012 4 3 0 142 *Coronary Artery Disease|MFGE8 protein, human|*Antigens, Surface|*Milk Proteins|Coronary Vessels|Atherosclerosis|Linkage Disequilibrium|Genome-Wide Association Study|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Endothelial Cells 30 ABI3BP 31174563 J. Exp. Clin. 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Pathol. 2019 10.1016/j.carpath.2019.05.004 0 0 0 185 Humans|Male|Aged, 80 and over|*Subarachnoid Hemorrhage|Cerebral Amyloid Angiopathy|Granulomatous Angiitis|*Amyloid|Imaging, Magnetic Resonance|*Amyloidogenic Proteins|Cerebral Hemorrhage|*Amyloidosis|Amyloid beta-Peptides|Neuroimaging|Brain|Tomography, X-Ray Computed 204 ABRA 31013542 Ecology 2019 10.1002/ecy.2663 0 0 0 185 Animals|Dogs|Ecosystem|Cingulata|Sloths|Armadillos|Myrmecophagidae|Mammals|Phylogeny|Biological Evolution|Argentina|Chile|Paraguay|Uruguay|Mexico 204 ABRA 30973920 PLoS ONE 2019 PMC6459512 10.1371/journal.pone.0215152 1 0 0 185 Humans|Animals|Dogs|Cattle|Horses|Brazil|Accidents, Traffic|Safety|Police|Animal, Wild|*Societies 204 ABRA 30842243 Oncologist 2019 PMC6656506 10.1634/theoncologist.2019-0078 0 0 0 185 Humans|Medical Student 204 ABRA 30834652 Hemodial Int 2019 10.1111/hdi.12741 0 0 0 185 Humans|*Renal Dialysis|*Prospective Studies|End Stage Renal Disease|Quality of Life|Fatigue|Time Factors 204 ABRA 30825817 Sci. Total Environ. 2019 10.1016/j.scitotenv.2019.02.338 2 0 0 185 Mediterranean Sea|*Climate Change|Habitat|Aquatic Organisms|Biodiversity|Animal Distribution|Salinity|Temperature 204 ABTB1 31390356 PLoS ONE 2019 PMC6685631 10.1371/journal.pone.0220441 1 0 0 20 Swine|Animals|*Brassica napus|*Transcriptome|Norway|*Meat|*Brassica rapa|Animal Feed|Diet|Body Composition|*Muscle, Skeletal|*Meal|Soy Bean|Genes, Regulator 31 ABTB1 31065369 United European Gastroenterol J 2019 PMC6488794 10.1177/2050640619837440 5 0 0 20 Humans|*Colorectal Cancer|MicroRNAs|HCT116 Cells|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Neoplasm Invasiveness|Cell Movement|Cell Proliferation|*Disease Progression|Down-Regulation|Cell Line, Tumor|*Neoplastic Processes|Repressor Proteins|Kaplan-Meier Estimate 31 ACAP2 31863774 Life Sci. 2019 10.1016/j.lfs.2019.117179 1 0 0 127 Female|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Neoplastic Processes|Cell Line, Tumor|Apoptosis|Disease Progression 26 ACAP2 31067441 Structure 2019 10.1016/j.str.2019.04.011 0 0 0 127 Rats|Animals|ADP-Ribosylation Factors|rab GTP-Binding Proteins|GTPase-Activating Proteins|Neurites|PC12 Cells 26 ACAP2 30905672 Structure 2019 10.1016/j.str.2019.02.008 2 5 0 127 Rats|Humans|Animals|ADP-Ribosylation Factors|rab GTP-Binding Proteins|GTPase-Activating Proteins|Neurites|Protein Transport|PC12 Cells|Protein Binding|Cell Movement|Ankyrin Repeat|RUSC2 protein, human|Carrier Proteins|RAB35 protein, human 26 ACOD1 31879990 Hepatology 2019 10.1002/hep.31093 0 0 0 3025 Mice|Humans|Animals|*Heme Oxygenase-1|*Liver Transplantation|*Cytoprotection|*Liver|Ischemia-Reperfusion Injury|Toll-Like Receptor 4|Signal Transduction|Macrophages|Mice, Inbred C57BL|*Transplant 24 ACOD1 31548418 Proc. 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Immunopharmacol. 2019 10.1016/j.intimp.2019.105872 0 0 0 15 Mice|Animals|*Cancer Vaccines|*Immunodominant Epitopes|Escherichia coli|*Mice, Inbred C57BL|*Vaccines, Peptide|incomplete Freund's adjuvant|Freund's Adjuvant|Vaccines, DNA|Immunizations|T-Lymphocytes, Cytotoxic|B16 Melanoma|ACRBP protein, human|SYCP1 protein, human|*Nuclear Proteins|Vaccination|Lipids|ACRBP protein, mouse|Acrosome 39 acrbp 31467409 Sci Rep 2019 PMC6715765 10.1038/s41598-019-49024-0 2 0 0 15 Humans|Swine|Male|Animals|*Sperm Capacitation|ATP dependent 26S protease|*Proteasome Endopeptidase Complex|Proteomics|Acrosome|Zona Pellucida|Fertilization|Spermatozoa|Sperm-Ovum Interactions|Ubiquitin|Proteasome Inhibitors|Ubiquitination|Mammals|Posttranslational Modification 39 acrbp 30917866 Biol. Res. 2019 PMC6438003 10.1186/s40659-019-0223-x 1 0 0 15 Male|Humans|*Testis|*Spermatogenesis|Spermatogonia|*Adult Germline Stem Cells|*Freezing|Sperm|Sertoli Cells|Cryopreservation|Infertility, Male|Stem Cells|Stem Cell Transplantation|Cells, Cultured 39 acrbp 30820981 Reprod. Domest. Anim. 2019 10.1111/rda.13426 2 0 0 15 Male|Animals|*Buffaloes|*Proteomics|*Spermatozoa|*Fertility|Proteome|Bioinformatics|*Bison|Protein Processing, Post-Translational|Two-Dimensional Difference Gel Electrophoresis 39 acrbp 30606959 J. Reprod. Dev. 2019 PMC6473115 10.1262/jrd.2018-137 0 0 0 15 Humans|Male|Female|Mice|Animals|*Sperm|Acrosome Reaction|proacrosin|Acrosin|Sperm-Ovum Interactions|Subfertility, Male|Acrosome|ACRBP protein, human|*Binding Protein|Fertilization|Zona Pellucida|Oocytes|Oviduct|*Genitalia, Female|Fallopian Tubes|Enzyme Precursors|ACRBP protein, mouse 39 ACRV1 31290539 Biol. Reprod. 2019 PMC6863968 10.1093/biolre/ioz115 0 1 0 6 Mice|Male|Animals|*Spermatids|Acrv1 protein, mouse|*Membrane Proteins|Spermatogenesis|*Regulatory Sequences, Nucleic Acid|Promoter Regions, Genetic|Testis|Acrosome|Mice, Transgenic|Transcription, Genetic|DNA-Binding Proteins|Nucleosome|Nuclear Protein 57 ACRV1 30646538 Int J Mol Sci 2019 PMC6359055 10.3390/ijms20020310 0 9 0 6 Cyclin-Dependent Kinase Inhibitor p21|Cyclin-Dependent Kinase Inhibitor p16|Downregulation|Cell Line, Tumor|Promoter Regions, Genetic 57 ACRV1 31290539 Biol. Reprod. 2019 PMC6863968 10.1093/biolre/ioz115 0 1 0 6 Mice|Male|Animals|*Spermatids|Acrv1 protein, mouse|*Membrane Proteins|Spermatogenesis|*Regulatory Sequences, Nucleic Acid|Promoter Regions, Genetic|Testis|Acrosome|Mice, Transgenic|Transcription, Genetic|DNA-Binding Proteins|Nucleosome|Nuclear Protein 57 ACRV1 30646538 Int J Mol Sci 2019 PMC6359055 10.3390/ijms20020310 0 9 0 6 Cyclin-Dependent Kinase Inhibitor p21|Cyclin-Dependent Kinase Inhibitor p16|Downregulation|Cell Line, Tumor|Promoter Regions, Genetic 57 ACTBP2 31005711 Forensic Sci. Int. 2019 10.1016/j.forsciint.2019.03.036 0 0 0 0 Humans|*Alleles|Gene Frequency|Genetics, Population|DNA Fingerprinting|Microsatellite Repeats|Ethnic Groups|Heterozygote|Polymerase Chain Reaction|Genotype|*Chinese|China 67 ACTBP2 30929752 Curr Probl Cancer 2019 10.1016/j.currproblcancer.2019.03.002 1 0 0 0 Humans|*Microsatellite Instability|*Urinary Bladder Neoplasms|*Pilot Projects|Egypt|Loss of Heterozygosity|Microsatellite 67 Activation of TRKA receptors 31871542 Oxid Med Cell Longev 2019 PMC6913242 10.1155/2019/2051235 1 0 0 0 *Reactive Oxygen Species|*Transcriptional Activation|FPR1 protein, human|*Receptors, Formyl Peptide|Oxidases, NADPH|N-Formylmethionine Leucyl-Phenylalanine|Signal Transduction|Phosphorylation|*Receptor Protein-Tyrosine Kinases 682 Activation of TRKA receptors 31720014 Acta Naturae 2019 PMC6826148 10.32607/20758251-2019-11-3-31-37 0 8 0 0 Rats|Animals|Phosphatidylinositol 3-Kinases|*Brain Ischemia|*Hippocampus|*Corpus Striatum|NGF protein, human|Nerve Growth Factor|*Neurogenesis|*Cerebral Infarction|*Dipeptides|*Neostriatum|Stroke|Neuroprotective Agents|trkA Receptor|*Central Nervous System Stimulants|Neuroprotection|*Gray Matter 682 Activation of TRKA receptors 31678682 Cell. 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Oncol. 2019 10.32471/exp-oncology.2312-8852.vol-41-no-4.13841 0 0 0 13 Humans|DNA Copy Number Variations|Leukovorin|5 Fluorouracil|Oxaliplatin|Colorectal Cancer|Cetuximab|Organoplatinum Compounds|Antineoplastic Combined Chemotherapy Protocols|Disease-Free Survival|Antibodies, Monoclonal|ErbB Receptors|Antibodies, Monoclonal, Humanized|*Colonic Neoplasms|*Rectal Neoplasms|Mutation 31 ADAM7 31666004 BMC Genomics 2019 PMC6822442 10.1186/s12864-019-6164-5 1 0 0 20 Humans|Swine|Animals|Male|*Genome-Wide Association Study|*Semen|*Phenotype|Quantitative Trait Loci|Semen Analysis|Sus scrofa|Sperm Motility|Genetic Association Studies|Genotype|Polymorphism, Single Nucleotide|Artificial Insemination|Genetic Selection|Pedigree|*Bodily Secretions 24 ADAMDEC1 31627897 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.10.073 0 2 0 24 Humans|Mice|Animals|*Rosacea|*Macrophages|*Dermatitis|Inflammation|ADAM Proteins|Skin|Disease Models, Animal|Adamdec1 protein, mouse 42 ADAMDEC1 31467500 Clin Proteomics 2019 PMC6712843 10.1186/s12014-019-9255-z 3 0 0 24 Humans|*Proteomics|*Colorectal Cancer|Occult Blood|Colonoscopy|Early Detection of Cancer|Biomarkers, Tumor|Plasma Proteins|*Colonic Neoplasms|Feces|Sensitivity and Specificity|Case-Control Studies 42 ADAMDEC1 31434712 Cancer Discov 2019 10.1158/2159-8290.CD-18-1308 2 1 0 24 *Cancer Stem Cells|Glioblastomas|Brain Tumors|*Signal Transduction|Cell Line, Tumor|Cell Proliferation|FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3 42 ADARB2 31552420 Nucleic Acids Res. 2019 PMC6846710 10.1093/nar/gkz815 0 0 0 83 34 ADARB2 31477183 Clin Epigenetics 2019 PMC6721173 10.1186/s13148-019-0729-7 0 0 0 83 34 ADARB2 31192139 Front Oncol 2019 PMC6549402 10.3389/fonc.2019.00448 0 0 0 83 34 ADARB2 31106880 Bioessays 2019 PMC6699488 10.1002/bies.201800239 0 0 0 83 34 ADARB2 30950019 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.04.010 0 0 0 83 34 ADGRG6 31873966 Glia 2019 PMC7148175 10.1002/glia.23769 0 0 0 122 Mice|Animals|*Peripheral Nerve Injuries|*Schwann Cells|*Neuromuscular Junction|Nerve Crush|Nerve Regeneration|Receptors, Cholinergic|*Receptors, G-Protein-Coupled|Gpr126 protein, mouse 42 ADGRG6 31652254 PLoS Genet. 2019 PMC6834287 10.1371/journal.pgen.1008096 1 0 0 122 Humans|Mice|Animals|*Intervertebral Disk|Intervertebral disc disease|Disk Degeneration|Herniated Disc|*Signal Transduction|Disease Models, Animal|*Receptors, G-Protein-Coupled|STAT3 protein, human|STAT3 Transcription Factor 42 ADGRG6 31596512 Ann. N. Y. Acad. Sci. 2019 10.1111/nyas.14245 0 0 0 122 Humans|Rats|Animals|HEK293 Cells|*Gene Expression Regulation|3' UTR|MicroRNAs|*Receptors, G-Protein-Coupled|Binding Site|mRNA|Zebrafish 42 ADGRG6 31529518 Ann. N. Y. Acad. Sci. 2019 PMC7189964 10.1111/nyas.14233 0 0 0 122 Animals|*Receptors, G-Protein-Coupled|Schwann Cells|Myelin|*Signal Transduction|Zebrafish|Zebrafish Proteins|MBP protein, human|Myelin Basic Protein|Peripheral Nervous System|Axons|Early Growth Response Protein 2|Glia|Nerves, Peripheral|*Neurogenesis 42 ADGRG6 31515243 Pharmacol. Rev. 2019 PMC6742926 10.1124/pr.119.018044 1 8 0 122 United States|ADGRE5 protein, human|G-Protein-Coupled Receptors|*Ligands|metabotropic glutamate receptor 8|Receptors, Metabotropic Glutamate|ADGRG1 protein, human|metabotropic glutamate receptor 7|metabotropic glutamate receptor 6|*Cell Membrane|metabotropic glutamate receptor 4|Binding Sites|Signal Transduction|Models, Molecular|Antigens, CD 42 ADGRG6 31391008 BMC Cancer 2019 PMC6686570 10.1186/s12885-019-5983-8 6 0 0 122 *RNA, Long Noncoding|*RNA, Micro|*mRNA|*Squamous Cell Carcinoma|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Ontology|Prognosis|Biomarkers, Tumor|Computational Biology|Transcriptome|Databases, Genetic|Kaplan-Meier Estimate|*Tongue 42 ADGRG6 31382924 BMC Cancer 2019 PMC6683537 10.1186/s12885-019-5948-y 1 0 0 122 Humans|*Crizotinib|Carcinoma, Non-Small-Cell Lung|*Protein-Tyrosine Kinases|Lung Cancer|*Proto-Oncogene Proteins|*Lung Adenocarcinoma|Protein Kinase Inhibitors|*Oncogenes|Oncogene Proteins, Fusion|*Oncogene Fusion|Gene Rearrangement|Drug Resistance, Neoplasm|Pyrazoles|Pyridines|*Oncogenesis|Mutation|ROS1 protein, human 42 ADGRG6 31215653 Ann. 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Sci. 2019 10.1111/nyas.14135 1 1 0 122 Humans|Adolescent|Mice|Animals|Adult|*Receptors, G-Protein-Coupled|Zebrafish Proteins|Schwann Cells|Zebrafish|Myelin Sheath|Signal Transduction|Nerve, Sciatic|Cartilage|Scoliosis|Mutations|Gpr126 protein, mouse 42 ADGRG6 31180326 Elife 2019 PMC6598766 10.7554/eLife.44889 1 1 0 122 Animals|*Zebrafish|Zebrafish Proteins|Receptors, G-Protein-Coupled|Schwann Cells|Myelin Sheath|Cyclic AMP|Signal Transduction|Peripheral Nervous System|Organogenesis 42 ADGRG6 30886859 Biomed Res Int 2019 PMC6388357 10.1155/2019/4678969 4 1 0 122 Humans|Adolescent|*Scoliosis|*Exon|Single Nucleotide Polymorphisms|Genetic Association Studies|Genetic Predisposition to Disease|Chinese|Linkage Disequilibrium|Genotype|*Receptors, G-Protein-Coupled|Alleles|*Kyphosis|*Chondrogenesis|Case-Control Studies|Cartilage 42 ADGRG6 30755618 Nat Commun 2019 PMC6372626 10.1038/s41467-019-08576-5 3 5 0 122 *Urinary Bladder Neoplasms|Endothelial Cells|*Mutations|*Sequencing, Whole Genome|Carcinoma, Transitional Cell|DNA Mutational Analysis|Genomics|Databases, Genetic|Biomarkers, Tumor|Genetic Predisposition to Disease|Computational Biology|Phenotype|Gene Expression Profiling|*Pathological Angiogenesis 42 AEBP1 31864713 Pathol. Res. Pract. 2019 10.1016/j.prp.2019.152790 1 0 0 112 Humans|*Cell Proliferation|*Glioma|*Apoptosis|Cell Movement|NF-kappa B|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Signal Transduction|Repressor Proteins|Carcinogenesis|Carboxypeptidases|Prognosis|*Neoplastic Processes|Adipocyte|AEBP1 protein, human 91 AEBP1 31601918 Sci Rep 2019 PMC6787275 10.1038/s41598-019-51068-1 1 5 0 112 *Down-Regulation|*Glioma|PTEN protein, human|*PTEN Phosphohydrolase|Glioblastoma|Brain Cancer|Cellular Proliferation|*Cell Death|Repressor Proteins|Carboxypeptidases|Signal Transduction|Apoptosis|Promoter Regions, Genetic|Mitochondria 91 AEBP1 31556145 Clin. Exp. Dermatol. 2019 10.1111/ced.14108 1 2 0 112 Humans|*Hair Follicle|*Basal Cell Carcinoma|*Cell Differentiation|*Neoplasms, Basal Cell|Skin Neoplasms 91 AEBP1 31462616 J. Atheroscler. Thromb. 2019 PMC7113137 10.5551/jat.49106 1 5 0 112 Humans|*Aortic Aneurysm, Abdominal|NF-kappa B|*Inflammation|Matrix Metalloproteinase 9|Matrix Metalloproteinases|AEBP1 protein, human|Carboxypeptidases|Repressor Proteins 91 AEBP1 31299062 PLoS ONE 2019 PMC6625715 10.1371/journal.pone.0219764 0 0 0 112 Humans|*Non-alcoholic Fatty Liver Disease|*Glucose|Hepatic Stellate Cells|Fibrosis, Liver|Liver|*Fibrosis|Hepatocytes|miRNAs|HepG2 Cells|Upregulation|*Palmitates|Downregulation|Cell Proliferation|Transcriptional Activation|AEBP1 protein, human|Carboxypeptidases|Repressor Proteins|MIRN372 microRNA, human 91 AEBP1 31256118 J. Alzheimers Dis. 2019 10.3233/JAD-181113 2 0 0 112 Humans|Female|Male|*Alzheimer Disease|*Transcriptome|*Mitochondrial Membranes|Neurofibrillary Tangles|*Temporal Lobe|Neurons|Gene Expression Profiling|mRNA|Brain|Mitochondria 91 AEBP1 31219650 Mol. Carcinog. 2019 10.1002/mc.23066 4 5 0 112 Humans|*Prognosis|Matrix Metalloproteinase 2|*Colonic Neoplasms|*Cell Proliferation|*Adenocarcinoma|CDH1 protein, human|E Cadherin|Cell Movement|*Neoplastic Processes|NF-kappa B|Gene Expression Regulation, Neoplastic|Signal Transduction|Repressor Proteins|Carcinogenesis|Cell Line, Tumor|Upregulation|*Cell Cycle|Antigens, CD 91 AEBP1 31176712 Brain Res. 2019 10.1016/j.brainres.2019.06.004 1 0 0 112 Humans|Animals|Mice|*Neurofibrillary Tangles|*Alzheimer Disease|tau Proteins|*Temporal Lobe|Brain|Hippocampus|Cognitive Impairment|Amyloid|Amyloidogenic Proteins|Gene Expression|RNA|AEBP1 protein, human|Carboxypeptidases|Repressor Proteins|Aebp1 protein, mouse 91 AEBP1 31022261 PLoS ONE 2019 PMC6483353 10.1371/journal.pone.0215913 7 0 0 112 Female|Pregnancy|Horses|Male|Animals|*Breeding|Haplotype|Homozygote|Genotype|Selection, Genetic|Genomes|*Sport|Phenotypes|Genomics|Polymorphism, Single Nucleotide|Fertility|Crossbreeding|Principal Component Analysis 91 AEBP1 30779088 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201902_17011 1 9 0 112 Humans|Child|*Tumor Suppressor Protein p53|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Signal Transduction|Gene Expression Regulation, Leukemic|Cell Proliferation|Cell Cycle|Apoptosis|Jurkat Cells|Cell Line, Tumor|Gene Expression Profiling|AEBP1 protein, human|Carboxypeptidases|Repressor Proteins 91 AEBP1 30759870 Genes (Basel) 2019 PMC6410021 10.3390/genes10020135 4 1 0 112 Humans|Ehlers-Danlos syndrome type 2|Ehlers-Danlos Syndrome|*Mutations|Collagen Type V|Connective Tissue Diseases|Collagen 91 AEBP1 30723390 Hereditas 2019 PMC6350372 10.1186/s41065-019-0083-y 9 0 0 112 Humans|*Urinary Bladder Neoplasms|Gene Regulatory Networks|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Survival Analysis 91 AEBP1 30668708 Hum. Mol. Genet. 2019 10.1093/hmg/ddz024 5 0 0 112 Adult|Humans|*Ehlers-Danlos Syndrome|*Alleles|Skin Abnormalities|*Mutations|Skin|Connective Tissue Diseases|Collagen|Joint Hypermobility|Extracellular Matrix|Cicatrix|AEBP1 protein, human|Carboxypeptidases|Repressor Proteins 91 AEBP1 30655737 Oncol Lett 2019 PMC6313171 10.3892/ol.2018.9623 4 1 0 112 Humans|Neoplasm Recurrence, Local|*Colorectal Cancer|RNA, Micro|Gene Expression Regulation, Neoplastic|Cell Proliferation|Biomarkers, Tumor|Apoptosis|Cell Movement|Kaplan-Meier Survival Curves|*Colonic Neoplasms|Lymphatic Metastasis|Disease-Free Survival|Cell Line, Tumor|Adipocytes|MIRN214 microRNA, human 91 AFAP1L2 31219645 Mol. Carcinog. 2019 10.1002/mc.23071 3 0 0 160 Humans|Animals|Neoplasm Recurrence, Local|*Cancer Stem Cells|Epithelial-Mesenchymal Transition|*Catenins|Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Cell Proliferation|Cell Movement|Adaptor Proteins, Signal Transducing|*Phenotype|Upregulation 30 AFAP1L2 30667096 Glia 2019 10.1002/glia.23583 4 9 0 160 Animals|Mice|Humans|pleiotrophin|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|HEK293 Cells|*Carrier Proteins|Protein Tyrosine Phosphatase, Receptor Type Z|*Cytokines|Oligodendrocyte|MBP protein, human|Myelin Basic Protein|Cell Differentiation|Cuprizone|PXN protein, human|Paxillin|Adaptor Proteins, Signal Transducing|Phosphorylation|*Neurogenesis|PTPase 30 AFF2 31859800 Rev Chilena Infectol 2019 10.4067/S0716-10182019000500591 0 0 0 75 Humans|Animals|*Risk Factors|Chile|*Hydatidosis|Zoonoses|Patient Discharge 108 AFF2 31859762 Rev Chilena Infectol 2019 10.4067/S0716-10182019000400403 0 0 0 75 Humans|*Antifungal Agents|Invasive Fungal Infections|*Prescription, Inappropriate|Antimicrobial Stewardship|Immunocompromised Host 108 AFF2 31859733 Rev Chil Pediatr 2019 10.32641/rchped.v90i5.1017 0 0 0 75 Child|Humans|*Cosmetics|Poison Control Centers|Household Products|*Household|Databases, Factual|*Poisons|*Pediatrics 108 AFF2 31784536 Nat Commun 2019 PMC6884579 10.1038/s41467-019-13477-8 4 2 0 75 Animals|*C9orf72 Protein|Amyotrophic Lateral Sclerosis 2, Juvenile|*Frontotemporal Dementia|*Alleles|Amyotrophic Lateral Sclerosis|DNA Repeat Expansion|Drosophila melanogaster|Drosophila|*Complement Factor B|RNA|3'-(1-butylphosphoryl)adenosine|Peptide Elongation Factors 108 AFF2 31344185 Rev Chil Pediatr 2019 10.32641/rchped.v90i3.782 0 0 0 75 Infant|Female|Humans|Child, Preschool|Child|Depression, Postpartum|Mothers|Child Development|Psychiatric Status Rating Scales|Surveys and Questionnaires 108 AFF2 31147444 J. 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Chem. 2019 PMC6615702 10.1074/jbc.RA119.008577 3 2 0 75 Humans|Positive Transcriptional Elongation Factor B|Transcriptional Elongation Factors|*Transcription Factors|tat Gene Products, Human Immunodeficiency Virus|Cyclin-Dependent Kinase 9|RNA Polymerase II|HIV-1|Gene Expression Regulation, Viral|Repressor Proteins|Transcription, Genetic|*Dimerization|Promoter Regions, Genetic|Super C resin|*Resin Cements|HeLa Cells|AFF4 protein, human 108 AFF2 31095234 Rev Chil Pediatr 2019 10.32641/rchped.v90i2.670 0 0 0 75 Humans|Child|Infant|*Gestures|*Down Syndrome|Vocabulary|Comprehension 108 AFF2 31095231 Rev Chil Pediatr 2019 10.32641/rchped.v90i2.724 0 0 0 75 Humans|Female|*Rett Syndrome|*Methyl-CpG-Binding Protein 2|DNA Mutational Analysis|Phenotype|Genotype|Mutation|Chile 108 AFF2 31095207 Rev Chilena Infectol 2019 10.4067/S0716-10182019000100083 0 0 0 75 Child|Humans|*Poliovirus Vaccine, Inactivated|*Immunization Schedule|Latin America|Poliovirus Vaccine, Oral|Poliomyelitis|Poliovirus|Vaccination|Pan American Health Organization|World Health Organization|Injections, Intramuscular|Immunization|*Family 108 AFF2 31011208 Nat. Med. 2019 PMC6558662 10.1038/s41591-019-0434-2 28 0 0 75 Immunotherapy|Antigens, Neoplasm|Head and Neck Neoplasms|Squamous Cell Carcinoma of Head and Neck|T-Lymphocytes, Cytotoxic|*Gene Fusions|Biomarkers, Tumor|Mutation 108 AFF2 30725051 Rev Med Chil 2019 10.4067/S0034-98872018001101351 0 0 0 75 Female|Humans|Middle Aged|*Multiple Myeloma|*Amyloidosis|Immunoglobulin lambda-Chains|Thalidomide|Bone Marrow|Plasma Cells|Biopsy 108 AFF2 30724986 Rev Med Chil 2019 10.4067/S0034-98872018001001205 0 0 0 75 Male|Humans|Female|Aged|Child, Preschool|*Squamous Cell Carcinoma|*Stomach|Stomach Neoplasms|*Upper Gastrointestinal Tract|Biopsy|Palliative Therapy|Fatal Outcome 108 AGAP1 31785816 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.11.147 0 6 0 202 Animals|GTPase-Activating Proteins|ADP-Ribosylation Factor|Actin|Cell Migration|Actin Cytoskeleton|Cytoskeleton|rho-Associated Kinases|Cell Line, Tumor|Binding Protein|Neoplasm Invasiveness 25 AGAP1 31700678 NPJ Genom Med 2019 PMC6828700 10.1038/s41525-019-0101-z 0 0 0 202 Humans|*Cerebral Palsy|Sequencing, Next-Generation|Genomics|Sequence Analysis, DNA|Genetic Predisposition to Disease|Heterogeneities, Genetic|Genetic Variation|Mutation|*Databases, Genetic|Cohort Studies 25 AIF1 31861889 Brain Sci 2019 PMC7017034 10.3390/brainsci10010006 0 0 0 1453 1672 AIF1 31818115 Ceska Gynekol 2019 1 2 0 1453 Female|*Tumor Markers|*Serum|S100 Protein Family|TFF3 protein, human|Trefoil Factor-3|*Tumor 1672 AIF1 31733666 Int. Rev. Neurobiol. 2019 10.1016/bs.irn.2019.10.018 0 1 0 1453 Animals|Mice|Rats|*Microglia|*Binge Drinking|*Rodents|*Rats, Sprague-Dawley|*Ethanol|*Hippocampus|Alcoholism|Alcohol Drinking|Number, Cell|Aging 1672 AJAP1 31820855 Cell. Physiol. Biochem. 2019 10.33594/000000188 2 6 0 135 Humans|Female|*HeLa Cells|*mRNA|*Wnt Signaling Pathway|beta Catenin|Long Non-Coding RNA|Gene Expression Regulation, Neoplastic|*Catenins|Cell Line, Tumor|DNA Methylation|RNA Interference|Epithelial-Mesenchymal Transition|Cell Proliferation|Promoter Regions, Genetic|RNA, Small Interfering|Up-Regulation|Cervical Cancer|TET1 protein, human|Mixed Function Oxygenases 58 AJAP1 31171012 J. Exp. Clin. Cancer Res. 2019 PMC6554977 10.1186/s13046-019-1252-6 0 15 0 135 Humans|*Breast Cancer 1 Protein|*Epidermal Growth Factor|beta Catenin|Prognosis|Cell Line, Tumor|*Catenins|Cell Proliferation|Wnt Signaling Pathway|Cell Transformation, Neoplastic|Apoptosis|Heterografts|Gene Expression|ErbB Receptors|AJAP1 protein, human|Cell Adhesion Molecules|EGFR protein, human 58 AJAP1 30673708 PLoS ONE 2019 PMC6343938 10.1371/journal.pone.0209181 0 0 0 135 Animals|*Egg Shell|*Genome-Wide Association Study|*Chickens|*Eggs|*Genomics|Genotype|Pigmentation|*Color|SNPs|Alleles|Phenotype|Genotype-Phenotype Association|Biliverdin 58 AJAP1 30597727 J. Cell. Mol. Med. 2019 PMC6349347 10.1111/jcmm.14062 5 6 0 135 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Epithelial-Mesenchymal Transition|*Liver Neoplasms|miRNAs|Gene Expression Regulation, Neoplastic|RNA, Long Noncoding|Cell Movement|Prognosis|Proto-Oncogene Proteins c-akt|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Disease Progression|AJAP1 protein, human|Cell Adhesion Molecules 58 AKAP4 31514070 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109422 1 0 0 1712 Rats|Animals|*Atrial Fibrillation|*Colchicine|Heart Atria|*Transcriptome|RNA, Messenger|Fibrosis|Signal Transduction|Bioinformatics|Gene Expression Profiling 93 AKAP4 31293647 J Cancer 2019 PMC6603414 10.7150/jca.30425 4 0 0 1712 93 AKAP4 31255637 Dev. Biol. 2019 10.1016/j.ydbio.2019.06.017 4 0 0 1712 Humans|Mice|Male|Animals|*Mice, Knockout|*Proteomics|*RNA|*Spermatogenesis|AKAP4 protein, human|*A Kinase Anchor Proteins|Sperm Flagellum|Spermatozoa|Sperm Motility|Testis|Infertility, Male|*Single-Cell Analysis 93 AKAP4 31146187 Theriogenology 2019 10.1016/j.theriogenology.2019.05.013 1 0 0 1712 Male|Humans|Animals|*Semen|*Buffaloes|*Proteomics|*Spermatozoa|Semen Analysis|Seminal Plasma Proteins|Fertility|Genitalia, Male|*Bison|Protein Interaction Maps|Spermatozoa Maturation|AKAP4 protein, human|A Kinase Anchor Proteins 93 AKAP4 31042615 Free Radic. Biol. Med. 2019 10.1016/j.freeradbiomed.2019.04.037 1 6 0 1712 Humans|Male|Mice|Animals|CHEK1 protein, human|*Checkpoint Kinase 1|*Centromere Protein B|Mad2 Proteins|M Phase Cell Cycle Checkpoints|Mitosis|*Fertilization in Vitro|Chromosome Segregation|Aneuploidy|2,5-dichloro-4-bromophenol|*Chlorophenols|Embryo, Mammalian|*Sex Chromosome Aberrations|Oxidative Stress|Sex Chromosomes|AKAP4 protein, human|A Kinase Anchor Proteins 93 AKAP4 30947075 Theriogenology 2019 10.1016/j.theriogenology.2019.03.011 1 0 0 1712 Humans|Horses|Male|Animals|Swine|*Semen|Sperm Motility|AKAP4 protein, human|*A Kinase Anchor Proteins|*Spermatozoa|Semen Preservation|Sperm Flagellum|Cryopreservation|Freezing|Spermatogenesis|*Biomarkers|*Bodily Secretions 93 AKAP4 30904354 Reprod. Biomed. Online 2019 10.1016/j.rbmo.2018.12.037 3 0 0 1712 Humans|Male|*Sperm Flagellum|*Infertility, Male|*Mutations|Spermatozoa|Microtubule Proteins|Whole Exome Sequencing|*Multiple Abnormalities|Cytoskeletal Proteins|Flagella|AKAP4 protein, human|A Kinase Anchor Proteins|DNAH1 protein, human|Dyneins 93 AKAP4 30844654 Theriogenology 2019 10.1016/j.theriogenology.2019.01.025 0 0 0 1712 Cattle|Animals|Male|Humans|*Spermatozoa|Semen Analysis|Infertility, Male|Semen|Sperm Motility|Conception|Spermatogenesis|RNA|Messenger RNA|Hybridization, Genetic|Gene Library|AKAP4 protein, human|A Kinase Anchor Proteins 93 AKTIP 31743734 Gastroenterology 2019 PMC7062591 10.1053/j.gastro.2019.11.019 1 4 0 222 Humans|Animals|*Leflunomide|*Inflammatory Bowel Disease|Intestinal Atresia, Multiple|Intestinal Atresia|Intestines|Intestinal Mucosa|Enterocolitis|Mutations|Apoptosis|Epithelial Cells|Proteins|Intestinal Obstruction|Disease Models, Animal|TTC7A protein, human 46 AKTIP 31648709 J. Am. Coll. Cardiol. 2019 10.1016/j.jacc.2019.08.1055 1 0 0 222 *Diabetes Mellitus, Type 2|Mendelian Randomization Analysis|Genome-Wide Association Study|Blood Glucose|Polymorphism, Single Nucleotide|Body Mass Index|Cardiovascular Diseases|*Phenotype|Blood Pressure|Risk Factors|Odds Ratio 46 AKTIP 30841855 BMC Gastroenterol 2019 PMC6404335 10.1186/s12876-019-0957-5 0 16 0 222 Barrett Esophagus|Esophageal Neoplasms|CTNNB1 protein, human|beta Catenin|*Signal Transduction|Adenocarcinoma|*Catenins|Disease Progression 46 ALCAM 31883226 Thorac Cancer 2019 PMC6997015 10.1111/1759-7714.13285 0 0 0 337 *Carcinoma, Non-Small-Cell Lung|*Activated-Leukocyte Cell Adhesion Molecule|*Lung Neoplasms|ALCAM protein, human|*Fetal Proteins|miRNAs|*Signal Transduction|*Cell Adhesion Molecules, Neuronal|*Antigens, CD|RNA Interference|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor 689 ALCAM 31869263 Curr. Eye Res. 2019 10.1080/02713683.2019.1656748 0 0 0 337 689 ALPK1 31610608 Cell. Microbiol. 2019 PMC7003488 10.1111/cmi.13126 2 0 0 500 Mice|Humans|Animals|Child|*Citrobacter rodentium|*Mice, Inbred C57BL|*Mice, Inbred C3H|Enteropathogenic Escherichia coli|Colon|Enterobacteriaceae Infections|Colitis|Cells, Epithelial|Host-Pathogen Interactions|Disease Models, Animal|ALPK1 protein, mouse|Protein Kinases 47 ALPK1 31557402 J. Cell. Mol. Med. 2019 PMC6815771 10.1111/jcmm.14643 3 6 0 500 Humans|Animals|Mice|CCL5 protein, human|*Chemokine CCL5|*Streptozocin|Diabetes Mellitus, Type 2|CCL2 protein, human|*Chemokine CCL2|Diabetic Nephropathies|Gout|Kidney|Mice, Transgenic|Chemokines|Monocytes|Fibrosis|Cultured Cells|ALPK1 protein, mouse|Protein Kinases 47 ALPK1 31486236 Helicobacter 2019 10.1111/hel.12644 1 0 0 500 Animals|Mice|Helicobacter Infections|Helicobacter pylori|*Helicobacter|*Inflammation|Peptic Ulcer|Bacterial Vaccines|Cytokines|Gastric Cancer|VacA protein, Helicobacter pylori|Bacterial Proteins|T-Cells, Regulatory|Myeloid Cells|Immune Tolerance|Cells, Epithelial|ALPK1 protein, mouse|Protein Kinases 47 ALPK1 31123889 Curr. Top. Microbiol. Immunol. 2019 10.1007/978-3-030-15138-6_7 0 1 0 500 Humans|*Helicobacter Infections|*Helicobacter pylori|*Signal Transduction|*Immunity, Innate|Type IV Secretion System|Nod1 Signaling Adaptor Protein|NF-kappa B|Pathogenicity Island|Cells, Epithelial|Antigens, Bacterial|TRAF-Interacting Protein|Adaptor Proteins, Signal Transducing|Interleukin-8|Upregulation|Transcription Factor|Bacterial Proteins|Cell Line|NOD1 protein, human 47 ALPK1 31101826 Nat Commun 2019 PMC6525246 10.1038/s41467-019-09979-0 1 0 0 500 Humans|*Acrospiroma|*Sweat Gland Neoplasms|*Carcinoma, Skin Appendage|*Mutation|Cylindroma|Familial cylindromatosis|Neoplastic Syndromes, Hereditary|Skin Neoplasms|Deubiquitinating Enzyme CYLD|Sweat Gland|Tumor Suppressor Proteins|Adenoma|Cell Transformation, Neoplastic 47 ALPK1 31075211 FASEB J. 2019 PMC6662969 10.1096/fj.201802555R 10 0 0 500 *Pathogen-Associated Molecular Pattern Molecules|*Heptoses|NF-kappa B|Immunity, Innate|Signal Transduction|Adaptor Proteins, Signal Transducing|Protein Kinases|Adenosine Diphosphate 47 ALPK1 31053777 Eur. J. Hum. Genet. 2019 PMC6777630 10.1038/s41431-019-0421-6 1 1 0 500 Child|Humans|*Stomatitis, Aphthous|*Adenitis|*Pharyngitis|*Fever|Pyrin|*Syndrome|Heterozygote|*Lymphadenopathy|*Disease Susceptibility|Pedigree|Cytoskeletal Proteins|*Genotype|*Amyloidosis|Mutation 47 ALPK1 31049845 Adv. Exp. Med. Biol. 2019 10.1007/5584_2019_360 1 0 0 500 Humans|*Helicobacter pylori|Helicobacter Infections|Type IV Secretion System|*Signal Transduction|*B-Lymphocytes|*Stomach|Urease|Pathogenicity Factors|Immunity, Innate|Host-Pathogen Interactions|Bacterial Proteins|Lipopolysaccharides 47 ALPK1 31030124 Blood Cells Mol. Dis. 2019 10.1016/j.bcmd.2019.04.010 0 0 0 500 *Prognosis|Gene Ontology|Gene Expression Profiling|Gene Regulatory Networks|Computational Biology|Gene Expression Regulation, Neoplastic|Databases, Genetic|Transcriptome|Biomarkers, Tumor|*Recurrence|Software|Acute Lymphoblastic Leukemia 47 ALPK1 30967659 Genet. Med. 2019 PMC6752478 10.1038/s41436-019-0476-3 1 0 0 500 Retinal Dystrophy|Genes, Recessive|Exome|Homozygote|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Pedigree|Retina|Phenotype|Mutation|*Syndrome|Mutation, Missense 47 ALPK1 30684847 Carbohydr. Res. 2019 10.1016/j.carres.2018.12.011 2 1 0 500 Animals|*Heptoses|Pathogen-Associated Molecular Pattern Molecules|lipopolysaccharide B|Lipopolysaccharides|Immunity, Innate|Escherichia coli|Gram Negative Bacteria|Immunologic Factors|Adenosine Diphosphate 47 ALPK1 30659231 Mucosal Immunol 2019 10.1038/s41385-019-0133-9 3 0 0 500 Mice|Animals|*T Cells|IL10 protein, human|Interleukin-10|Colitis|Mice, Inbred C57BL|*Microbiome|Mice, Knockout|Colon|Adoptive Transfer|Bone Marrow Cells|*Hematopoietic System 47 Alx3 31492950 Sci Rep 2019 PMC6731288 10.1038/s41598-019-49116-x 0 2 0 60 Humans|Mice|Animals|*Genes, Homeobox|*Tooth|Homeodomain Proteins|MSX1 Transcription Factor|Transcription Factors|Tooth Germ|Mesoderm|Morphogenesis|Gene Expression Regulation, Developmental|*Mammals 65 Alx3 31275359 Front Genet 2019 PMC6593342 10.3389/fgene.2019.00583 1 0 0 60 Animals|*Camelids, New World|*Biological Phenomena|*Color|*Dietary Fiber 65 Alx3 31114073 Nat Mater 2019 PMC7362336 10.1038/s41563-019-0368-6 0 0 0 60 Animals|Vascular Endothelial Growth Factor A|Regeneration|Tissue Scaffolds|Tissue Engineering|*Enamel Organ|Cell Differentiation|Tooth|Odontoblast|Wnt Pathway|Animal Model|*Wound Healing 65 Alx3 30938152 Inorg Chem 2019 10.1021/acs.inorgchem.8b02630 0 0 0 60 *Boranes|*Ammonia|Hydrogen|Temperature 65 Alx3 30905259 J. 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UOEH 2019 10.7888/juoeh.41.317 0 0 0 255 Angiopoietins|Angiopoietin-like Proteins|*Neoplastic Processes|Lipid Metabolism|Neovascularization, Physiologic|Neovascularization, Pathologic|Cancer|Carcinogenesis|Inflammation|Hematopoietic Stem Cells 67 ANGPTL1 31223079 Curr. Med. Chem. 2019 10.2174/0929867326666190621120523 1 0 0 255 Humans|Angiopoietin-like Proteins|Angiopoietins|*Atherosclerosis|Triglycerides|Lipid Metabolism|Peptide Hormones|Liver|ANGPTL3 protein, human|ANGPTL8 protein, human 67 ANGPTL1 31103265 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.05.078 1 1 0 255 Humans|*Bortezomib|*RNA, Long Noncoding|*Multiple Myeloma|MicroRNAs|Drug Resistance, Neoplasm|Cell Proliferation|Cell Line, Tumor|Apoptosis|Bone Marrow|ANGPTL1 protein, human|Angiopoietin-like Proteins 67 ANGPTL1 30755815 Am J Cancer Res 2019 PMC6356919 5 5 0 255 Humans|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*Liver Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Downregulation|Genes, Tumor Suppressor|Cell Movement|Upregulation|Cell Line, Tumor|Cell Proliferation|*Neoplastic Processes|Oncogenesis|Disease Progression|ANGPTL1 protein, human|Angiopoietin-like Proteins|Mirn182 microRNA, human 67 ANGPTL1 30688091 Epigenomics 2019 PMC6371847 10.2217/epi-2018-0150 2 12 0 255 *Epigenesis, Genetic|Angiopoietins|*Epigenetics|*Atherosclerosis|Angiopoietin-like Proteins 67 ANGPTL1 30610511 Cytotechnology 2019 PMC6368512 10.1007/s10616-018-0259-8 1 2 0 255 Humans|*Epithelial-Mesenchymal Transition|*Colorectal Cancer|Vimentin|HCT 116 Cells|Prognosis|Cell Movement|MicroRNAs|Cell Proliferation|Neoplasm Staging|Cell Line, Tumor|*Colonic Neoplasms|Apoptosis|Lymphatic Metastasis|Angiopoietin-like Proteins 67 ANGPTL2 31840173 Nephrol. 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Biochem. 2019 10.1080/09168451.2019.1702871 0 3 0 343 Mice|Animals|oxidized low density lipoprotein|orientin|*Lipoproteins, LDL|*Atherosclerosis|*Macrophages|*Flavonoids|*Glucosides|Foam Cells|*Inflammation|*Oxidative Stress|Scavenger Receptors, Class E|RAW 264.7 Cells 204 ANGPTL2 31743976 J Exerc Nutrition Biochem 2019 PMC6823644 10.20463/jenb.2019.0021 0 0 0 343 Humans|Male|*Vascular Stiffness|*Angiopoietin-like Protein|*Overweight|*Obesity|Weight Loss|Body Mass Index|Pulse Wave Analysis|Cardiovascular Disease|Exercise|Risk Factors|ANGPTL2 protein, human 204 ANGPTL2 31737187 Am J Transl Res 2019 PMC6834488 0 3 0 343 204 ANGPTL2 31727773 Genes Dev. 2019 PMC6942048 10.1101/gad.329417.119 0 0 0 343 Mice|Animals|*Signal Transduction|Angiopoietin-like Protein|*Neoplastic Processes|Tumor Microenvironments|Angiopoietins|Cell Line, Tumor|Melanoma|Angptl2 protein, mouse 204 ANGPTL2 31713234 Dev. Growth Differ. 2019 10.1111/dgd.12635 0 0 0 343 Animals|Xenopus laevis|*Limb|Xenopus Proteins|*Signal Transduction|*Transcriptome Analysis|Animals, Genetically Modified|Regeneration|Epidermal Cells|*B-Lymphocytes|Epidermis|enhanced green fluorescent protein|Green Fluorescent Proteins|Fibroblast Growth Factor|Larva|Slit1 protein, Xenopus|Nerve Tissue Proteins 204 ANGPTL2 31709175 Front Oncol 2019 PMC6823876 10.3389/fonc.2019.01063 0 0 0 343 204 ANGPTL2 31632523 Am J Transl Res 2019 PMC6789235 0 0 0 343 Animals|*Diabetic Nephropathies|*Angiopoietin-like Protein|*Fibrosis|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|*Autophagy|MAP2K1 protein, human|*MAP Kinase Kinase 1|Kidney|Diabetes Mellitus, Experimental|*Disease Progression|Transforming Growth Factor beta1|2,5-dichloro-4-bromophenol|*Chlorophenols|*Urinary Tract 204 ANGPTL6 31336494 Diabetes Metab Syndr 2019 10.1016/j.dsx.2019.02.022 0 2 0 149 Adult|Humans|Female|*Adipokines|*Antioxidants|*Obesity|*Diet|Retinol-Binding Proteins, Plasma|Triglycerides|Biomarkers 66 ANGPTL6 31146977 Pathol. 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Res. 2019 10.1093/ntr/ntz240 1 0 0 58 Humans|*Tobacco Use Disorder|*Smokers|*Asian Continental Ancestry Group|Haplotypes|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|*Neural Cell Adhesion Molecules|Genotype|European Continental Ancestry Group|Smoking|Receptors, Dopamine D2|Genetic Variation|Protein-Serine-Threonine Kinases|Epigenesis, Genetic|TTC12 protein, human|Proteins|ANKK1 protein, human 276 ANKK1 31851973 Lifestyle Genom 2019 10.1159/000504603 0 0 0 58 Adult|Humans|Quebec|*Genotype|*Cohort Studies|Receptors, Dopamine D2|Genetic Predisposition to Disease|Alleles|Polymorphism, Single Nucleotide|Interactions, Gene-Environment|*Food|*Diet|Protein-Serine-Threonine Kinases|ANKK1 protein, human|DRD2 protein, human 276 ANKK1 31766642 Nutrients 2019 PMC6949992 10.3390/nu11122863 0 1 0 58 Gene Frequency|Receptors, Dopamine D2|Genetic Predisposition to Disease|Polymorphism, Genetic|Genotype|Case-Control Studies|Protein-Serine-Threonine Kinases 276 ANKK1 31708815 Front Psychiatry 2019 PMC6821788 10.3389/fpsyt.2019.00755 0 0 0 58 Humans|*N-Methyl-3,4-methylenedioxyamphetamine|*Dopamine|DRD4 protein, human|Receptor, Dopamine D4|SLC6A3 protein, human|Dopamine Transporter|DRD2 protein, human|Single Nucleotide Polymorphisms|Genetic Association Studies|Genetic Predisposition to Disease|Minisatellite Repeats|Alleles 276 ANKK1 31702801 JAMA Netw Open 2019 PMC6902783 10.1001/jamanetworkopen.2019.14940 1 2 0 58 *Alcoholism|Genome-Wide Association Study|*Frequencies, Allele|Genetic Predisposition to Disease|Receptors, Dopamine D2|Genotype|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Phenotype|Protein-Serine-Threonine Kinases|Case-Control Studies 276 ANKK1 31559529 Eur Arch Psychiatry Clin Neurosci 2019 10.1007/s00406-019-01072-3 0 0 0 58 Male|Humans|*Craving|*Alcoholism|*Dopamine|*Aggression|Republic of Korea|*Impulsivity|Alcohol-Related Disorder|Alcohol Drinking|Variable Number of Tandem Repeats|Reward|Alleles|Genotype|Single Nucleotide Polymorphisms 276 ANKK1 31502081 Curr Top Behav Neurosci 2019 10.1007/7854_2019_113 0 0 0 58 *Memory, Short-Term|*Dopamine|*Mental Health|Cortex, Prefrontal|Catechol O-Methyltransferase|Executive Function|Memory Disorders|Genetic Variation 276 ANKK1 31404557 Behav. Brain Res. 2019 10.1016/j.bbr.2019.112148 3 0 0 58 *Dopamine|*Exercise|*Reinforcement, Psychology|*Reward|Sedentary Behavior|Genotypes|Genetic Variation 276 ANKK1 31403319 Can J Nurs Res 2019 10.1177/0844562119863612 0 0 0 58 Child|Humans|*Parenting|Prospective Studies|Child Behavior Disorders|Genotype 276 ANKK1 31357601 Int J Environ Res Public Health 2019 PMC6695683 10.3390/ijerph16152687 1 0 0 58 *Ankyrin Repeat|*Polymorphism, Genetic|*Personality|Gene Frequency|Personality Inventory|Genotype 276 ANKK1 31331851 J Craniomaxillofac Surg 2019 10.1016/j.jcms.2019.05.001 0 1 0 58 *Orthognathic Surgery|*Quality of Life|*Orthognathic Surgical Procedures|Dentofacial Deformities|Surveys and Questionnaires|*Facial Bones|*Reproductive History 276 ANKRD17 31661072 Elife 2019 PMC6861002 10.7554/eLife.48601 0 1 0 122 Animals|*Active Transport, Cell Nucleus|Drosophila Proteins|Drosophila melanogaster|Nuclear Proteins|Trans-Activators|Intracellular Signaling Peptides and Proteins|Transcription Factors|Protein-Serine-Threonine Kinases|Signal Transduction|TYRP1 protein, human|*Membrane Glycoproteins|Cell Nucleus|Gene Expression Regulation, Developmental|Mask protein, Drosophila|DNA-Binding Proteins 24 ANKRD17 31175513 Mol. Biol. Rep. 2019 10.1007/s11033-019-04904-6 0 0 0 122 Pregnancy|Female|Animals|*Litter Size|*Goats|*Sequencing, Whole Genome|Genome|Breeding|Fertility|Genotype|Polymorphism, Single Nucleotide 24 ANKRD17 30933928 Reproduction 2019 PMC6773536 10.1530/REP-19-0037 4 0 0 122 Cattle|Animals|Female|Humans|*Transcriptome|*Granulosa Cell|Ovarian Follicles|Follicular Fluid|Transcriptome Analysis|*Uterine Disease|Gene Expression Regulation|Postpartum|Estradiol 24 ANLN 31822116 Cell Transplant 2019 PMC7016461 10.1177/0963689719893950 1 0 0 272 *Carcinoma, Hepatocellular|*Computational Biology|*Liver Neoplasms|*Prognosis|Protein Interaction Maps|Gene Expression Profiling|Gene Ontology|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Upregulation|Microarray Analysis|Liver|Signal Transduction|Asia 92 ANLN 31779055 J. Cell. Mol. Med. 2019 PMC6991688 10.1111/jcmm.14719 2 0 0 272 Humans|*Prognosis|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Lung Adenocarcinoma|CD274 protein, human|B7-H1 Antigen|Biomarkers, Tumor|Adenocarcinoma|Genes, erbB-1|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Bioinformatics|Databases, Genetic|Transcriptome 92 ANLN 31766561 Cancers (Basel) 2019 PMC6966660 10.3390/cancers11121840 1 1 0 272 92 ANLN 31756998 J Clin Med 2019 PMC6947147 10.3390/jcm8122026 0 0 0 272 Female|Humans|*Granulosa Cells|Ovarian Follicle|Ovulation|Cell Cycle|Progesterone|Spindle Apparatus|M Phase Cell Cycle Checkpoints|*Cell Nucleus Division|Fertilization in Vitro|Cells, Cultured 92 ANP32E 31858592 J. Cell. Physiol. 2019 10.1002/jcp.29414 1 0 0 183 Humans|*Protein Phosphatase 2A|*Cell Cycle|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|CDC2 Protein Kinase|*Cell Cycle Proteins|Cyclins|Cyclin-Dependent Kinases|Phosphorylation|Signal Transduction|Cell Line, Tumor|Cell Cycle Checkpoints|*Cell Division|Genes, cdc|Gene Expression Regulation, Neoplastic|*Biochemical Phenomena|*Data Mining 36 ANP32E 31581291 J. Infect. Dis. 2019 10.1093/infdis/jiz506 2 0 0 183 Humans|Animals|*Influenza in Birds|*Influenza A virus|ANP32A protein, human|Intracellular Signaling Peptides and Proteins|RNA Replicase|Virus Replication|Influenzavirus B|Viral Proteins|Influenza, Human|Specificity, Host Species|RNA-Binding Proteins|Nuclear Proteins|Chickens 36 ANP32E 31404908 Blood Cells Mol. Dis. 2019 10.1016/j.bcmd.2019.102352 3 0 0 183 Humans|Child|MIRN150 microRNA, human|miRNA|MIRN100 microRNA, human|lncRNA|mRNA|Gene Regulatory Networks|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Leukemia, Myeloid, Acute|Kaplan-Meier Estimate|ERMP1 protein, human|Peptide Hydrolases|MYO1B protein, human|Myosin Type I|PAPD7 protein, human|Chromosomal Proteins, Non-Histone|DNA-Directed DNA Polymerase 36 ANXA10 31807177 Oncol Lett 2019 PMC6876331 10.3892/ol.2019.11025 2 0 0 63 Humans|Male|Female|*Annexins|*Prognosis|Annexin A2|Biomarkers, Tumor|Survival Rate|*Liver Cancer|Proteins 62 ANXA10 31789399 Oncol. Rep. 2019 10.3892/or.2019.7422 0 0 0 63 Humans|*Stomach Neoplasms|*Organoids|antineoplaston A10|Annexins|Immunohistochemistry|*Pancreas|Adenocarcinoma|Cell Proliferation|Biomarkers, Tumor|Stomach|Cell Cycle 62 ANXA10 31585123 Gastroenterology 2019 PMC6902245 10.1053/j.gastro.2019.09.026 0 0 0 63 Mice|Humans|Animals|*Stomach Neoplasms|*Stomach|Mice, Transgenic|Gastric Mucosa|Cell Transformation, Neoplastic|Cell Proliferation|Mutation|Disease Models, Animal 62 ANXA10 31492557 EBioMedicine 2019 PMC6796529 10.1016/j.ebiom.2019.08.062 5 8 0 63 *Dinoprostone|*Extrahepatic Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|STAT3 protein, human|*STAT3 Transcription Factor|*Phospholipases A2, Cytosolic|Prognosis|Epithelial-Mesenchymal Transition|Signal Transduction|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Neoplastic Processes|Disease Progression 62 ANXA10 31363077 Med. Sci. Monit. 2019 PMC6686714 10.12659/MSM.915911 2 0 0 63 Humans|Female|*Carcinoma, Ovarian Epithelial|*Prognosis|Ovarian Cancer|Apoptosis|antineoplaston A10|Cell Line, Tumor|*Cystadenocarcinoma, Serous|Immunohistochemistry|Kaplan-Meier Survival Curves|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Neoplasm Staging|Cell Proliferation|Annexins 62 ANXA10 31211760 Clin Transl Gastroenterol 2019 PMC6613862 10.14309/ctg.0000000000000053 2 0 0 63 Humans|Mice|Animals|*Duodenal Neoplasms|*Familial Adenomatous Polyposis|*Adenoma|*Jejunal Neoplasms|*Carcinoma|*Gene Expression 62 ANXA10 31208343 BMC Neurosci 2019 PMC6580616 10.1186/s12868-019-0513-9 0 14 0 63 Humans|Rats|Animals|*Matrix Metalloproteinase 9|antineoplaston A10|*Pain, Neuropathic|Hyperalgesia|Spinal Cord|Rats, Sprague-Dawley|NF-kappa B|Astrocytes|Tumor Necrosis Factor-alpha|Signal Transduction|Disease Models, Animal|Annexins 62 ANXA10 31052599 Cancers (Basel) 2019 PMC6562482 10.3390/cancers11050618 0 3 0 63 62 ANXA10 30953499 BMC Cancer 2019 PMC6451218 10.1186/s12885-019-5548-x 1 0 0 63 *Proteomics|*Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|*Pancreatic Neoplasms|Immunohistochemistry|Biomarkers, Tumor|Diagnosis, Differential 62 ANXA10 30791866 BMC Genomics 2019 PMC6385435 10.1186/s12864-019-5518-3 1 11 0 63 Animals|Cattle|*Genome-Wide Association Study|*Meat|Quantitative Trait Loci|Phenotypes|Genotype|Breeding|Chromosome Mapping|Red Meat|Genomics|Polymorphism, Single Nucleotide 62 ANXA10 30758105 Pathol. Int. 2019 PMC6850125 10.1111/pin.12771 0 1 0 63 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Macrophages|Carcinoma, Squamous Cell|Tumor Microenvironment|Cell Line, Tumor|Neovascularization, Pathologic|Disease Progression 62 ANXA10 30744186 J Clin Med 2019 PMC6406441 10.3390/jcm8020229 1 1 0 63 Humans|*Squamous Cell Carcinoma of Head and Neck|antineoplaston A10|*Papillomavirus Infections|*Annexins|Colorectal Neoplasms|Adenocarcinoma|Biomarkers, Tumor|Downregulation|Head and Neck Neoplasms|Cell Differentiation|ANXA9 protein, human 62 ANXA3 31772502 Mediators Inflamm. 2019 PMC6854216 10.1155/2019/4567106 0 0 0 152 Humans|*Down Syndrome|*Periodontal Disease|Periodontitis|*Inflammation|Periodontal Index 125 ANXA3 31638091 Neural Regen Res 2019 PMC6975135 10.4103/1673-5374.266924 1 0 0 152 Humans|*Transcriptome|*Head Trauma|Brain Concussion|Traumatic Brain Injury|*Extracellular Vesicles|*Inflammation|Biomarkers|Neuropsychological Tests|Emergency Department|LTB4R2 protein, human|Receptors, Leukotriene B4 125 ANXA3 31524248 Mol Med Rep 2019 PMC6691243 10.3892/mmr.2019.10513 0 2 0 152 *Annexin A3|*Osteosarcoma|Bone Neoplasms|Apoptosis|Cell Proliferation|Cell Cycle|RNA, Small Interfering|Osteoblasts|Cell Movement|mRNA|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Transfection|Downregulation|Flow Cytometry 125 ANXA3 31372726 Eur Arch Psychiatry Clin Neurosci 2019 10.1007/s00406-019-01048-3 0 0 0 152 Humans|*Annexin A3|*Annexins|Cell Proliferation|Apoptosis|*Schizophrenia 125 ANXA3 31362241 Mol Ther Nucleic Acids 2019 PMC6661453 10.1016/j.omtn.2019.06.005 2 8 0 152 *Intracranial Aneurysm|*MAP Kinase Signaling System|Signal Transduction|c-jun N-Terminal Kinase|Myocytes, Smooth Muscle|Aneurysm, Ruptured|Apoptosis|Annexin A3|RNA, Small Interfering|*Annexins|Cell Proliferation|Muscle, Smooth, Vascular|CASP3 protein, human|Caspase 3|Cell Cycle|Cell Movement|Phosphorylation|Matrix Metalloproteinase 9 125 ANXA3 31276768 Toxicol. 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Anim. 2019 10.1007/s11626-019-00336-5 0 0 0 243 Swine|Animals|Proteomics|*Embryonic Stem Cells|*Cell Line|*Pancreas|*Pancreatic Duct|*Uroplakin|Cell Lineage|Cell Differentiation|Cell Culture Techniques|Exocrine Pancreas|Transcription Factors|Liver 71 ANXA4 30673304 Am. J. Physiol., Cell Physiol. 2019 10.1152/ajpcell.00404.2018 3 5 0 243 Pregnancy|Humans|Female|Rats|Animals|*Phosphoinositide 3 Kinase|*Pre-Eclampsia|*Trophoblasts|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Annexin A4|NOS3 protein, human|*Nitric Oxide Synthase Type III|Cell Line, Tumor|Placenta|Cell Movement|Matrix Metalloproteinase 2|Matrix Metalloproteinase 9|Signal Transduction|Cell Proliferation|Downregulation|Phosphorylation|Apoptosis 71 ANXA4 30664195 Int. J. Oncol. 2019 10.3892/ijo.2019.4690 2 0 0 243 Humans|*Cisplatin|*A549 Cells|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Isotope Labeling|*Amino Acids|*Apoptosis|*Autophagy|Drug Resistance, Neoplasm|Antineoplastic Agents|Cell Proliferation|Gene Expression Regulation, Neoplastic|Upregulation|G-T mismatch-binding protein|DNA-Binding Proteins|Downregulation 71 anxa8 31886193 Biomed Res Int 2019 PMC6925802 10.1155/2019/2816959 0 0 0 85 Rats|Animals|*RNA, Long Noncoding|*Transcriptome|*Sodium Chloride, Dietary|*Hypertension|Rats, Inbred Dahl|Blood Pressure|*Sodium Chloride|Kidney|*Whole Exome Sequencing 33 anxa8 31474227 J Transl Med 2019 PMC6717992 10.1186/s12967-019-2023-z 2 0 0 85 Humans|Female|*Annexins|*Prognosis|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|Cell Movement|RNA, Messenger|Apoptosis|Biomarkers 33 anxa8 30678048 Cancers (Basel) 2019 PMC6407115 10.3390/cancers11020130 2 16 0 85 *Carcinoma, Intraductal, Noninfiltrating|*Morphogenesis|Gene Expression Regulation, Neoplastic|*B-Lymphocytes|*Biomarkers|Cell Line, Tumor|Cell Proliferation|Annexin A8|Epithelial Cells 33 anxa8 30632236 Mol. Reprod. Dev. 2019 10.1002/mrd.23109 0 0 0 85 Pregnancy|Female|Swine|Animals|*RNA, Long Noncoding|*Endometrium|Implantation, Embryo|mRNA|Uterus|FGL2 protein, human|*Fibrinogen|Embryo, Mammalian|Pigs, Domestic 33 AOAH 31741788 PeerJ 2019 PMC6858983 10.7717/peerj.7976 0 0 0 51 *RNA, Long Noncoding|*Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate|Gene Regulatory Networks|ROC Curve|Multivariate Analysis 51 AOAH 31322475 Physiol. Genomics 2019 10.1152/physiolgenomics.00013.2019 2 0 0 51 Swine|Animals|*Lipopolysaccharides|*Colon|*Innate Immune Response|Animal Nutritional Physiological Phenomena|Animal Feed|Eating|Gene Expression Regulation|Cytokines|Carrier Proteins 51 AOAH 31017816 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2019 PMC6732428 10.1152/ajpregu.00029.2019 1 5 0 51 AHR protein, human|*Receptors, Aryl Hydrocarbon|acyloxyacyl hydrolase|Corticotropin Releasing Factor|Pituitary-Adrenal System|Hypothalamo-Hypophyseal System|*Basic Helix-Loop-Helix Transcription Factors|*Carboxylic Ester Hydrolases|Paraventricular Hypothalamic Nucleus|Corticosterone|Adrenocorticotropic Hormone|Receptors, Glucocorticoid|Stress, Psychological 51 APEX2 31828326 Nucleic Acids Res. 2019 PMC7038996 10.1093/nar/gkz1175 1 5 0 111 Humans|Animals|APEX1 protein, human|*DNA-(Apurinic or Apyrimidinic Site) Lyase|*DNA Breaks, Single-Stranded|DNA Repair|*Signal Transduction|DNA Damage|XRCC1 protein, human|X-ray Repair Cross Complementing Protein 1|Xenopus laevis|Endonucleases|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|DNA 121 APEX2 31760040 J Proteomics 2019 PMC6938231 10.1016/j.jprot.2019.103595 0 0 0 111 *Chlamydia trachomatis|*Eukaryotes|*Inclusion Bodies|Chlamydia Infections|Bacterial Proteins|Membrane Proteins|*Mass Spectrometry|*Chromatography, Affinity|Host-Pathogen Interactions|Vacuoles|*Membrane|*Eukaryotic Cells 121 APEX2 31719114 J. Cell Biol. 2019 PMC7039203 10.1083/jcb.201901097 0 0 0 111 *Mass Spectrometry|Isotope Labeling, Stable|*Organelles|Isotopes|*Lysosomes|Proteins|Stereocilia|*Proteolysis 121 APEX2 31544310 EMBO Rep. 2019 PMC6832005 10.15252/embr.201948150 4 4 0 111 *Active Transport, Cell Nucleus|exportin 1 protein|*Karyopherins|*Receptors, Cytoplasmic and Nuclear|Cell Nucleus|*Autophagy|Saccharomyces cerevisiae Proteins|Protein-Serine-Threonine Kinases|Cytoplasm|Protein Binding|Beclin1|Phosphorylation 121 APEX2 31519755 J. Biol. Chem. 2019 PMC6827323 10.1074/jbc.RA118.007283 7 2 0 111 Humans|*Nuclear Envelope|*Peroxidase, Ascorbate|*Proteomics|*Rapamycin|emerin|Membrane Proteins|Endoplasmic Reticulum|Nuclear Proteins|VAPB protein, human|Vesicular Transport Proteins|Protein Transport|HeLa Cells|Isotope Labeling, Stable 121 APOBEC3D 31429796 Hum. Genomics 2019 PMC6700979 10.1186/s40246-019-0231-5 0 0 0 83 *Transcriptome|Genome-Wide Association Study|*Multiple Myeloma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Quantitative Trait Loci|Gene Expression Profiling|Genotype 32 APOBEC3D 31145054 J. Gen. Virol. 2019 PMC7176283 10.1099/jgv.0.001276 1 0 0 83 *HIV-1|*THP-1 Cell Line|vif Gene Products, Human Immunodeficiency Virus|APOBEC-3G Deaminase|Cytosine Deaminase|Virus Replication|HIV Infections|Cytidine Deaminase|Proviruses|CD4 Positive T Lymphocytes|Mutation|*HIV Seropositivity|Cell Lines|Myeloid Cell 32 APOBEC3D 30660178 BMC Med. Genet. 2019 PMC6339282 10.1186/s12881-018-0740-4 2 0 0 83 Humans|*HIV-1|South Africa|*HIV Infections|vif Gene Products, Human Immunodeficiency Virus|APOBEC-3G Deaminase|Cytosine Deaminase|Cytidine Deaminase|Virus Replication|Aminohydrolases|DNA, Viral|Mutation|Africa, Northern|APOBEC3 protein, human 32 ARL4C 31774870 PLoS ONE 2019 PMC6881023 10.1371/journal.pone.0225721 0 0 0 179 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Drug Resistance, Neoplasm|Biomarkers, Tumor|Kidney|Tumor Cells, Cultured|Apoptosis|FN1 protein, human|Fibronectin|*Cell Lines|ARL4C protein, human|ADP-Ribosylation Factors 38 ARL4C 30906638 Am J Cancer Res 2019 PMC6405968 3 0 0 179 Humans|*Carcinoma, Renal Cell|*ADP-Ribosylation Factor|Kidney Neoplasms|Prognosis|Immunohistochemistry|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Transcriptome Analysis|Cohort Studies 38 ARL4C 30704470 BMC Med Genomics 2019 PMC6357449 10.1186/s12920-018-0467-2 2 0 0 179 Humans|*Glucocorticoids|*Transcriptome|NR3C1 protein, human|Glucocorticoid Receptor|*Cells, Epithelial|*Cell Lines|Adrenergic beta-2 Receptor Agonists|Asthma|Bronchi|Respiratory Mucosa|Transcription, Genetic|Corticosteroids 38 ARL4C 30647122 Mol. Cancer Ther. 2019 10.1158/1535-7163.MCT-18-0824 5 3 0 179 Humans|Adult|*Liver Neoplasms|Carcinoma, Hepatocellular|*Oligonucleotides, Anti-Sense|ADP-Ribosylation Factor|Colorectal Cancer|Lung Cancer|Gene Expression Regulation, Neoplastic|*Liver|Cell Proliferation|Cell Movement|Signal Transduction|siRNA|ARL4C protein, human 38 ARL4C 30640082 Environ. Res. 2019 10.1016/j.envres.2019.01.001 2 1 0 179 Humans|Male|Pregnancy|Female|Adult|*Polychlorinated Biphenyls|*Dibenzofurans, Polychlorinated|*DNA Methylation|Dioxins|Environmental Pollutants|Benzofurans|Environmental Exposure|Cohort Studies|Prenatal Exposure Delayed Effects|*Parturition 38 ARMS2 31884580 Adv. Exp. Med. Biol. 2019 10.1007/978-3-030-27378-1_1 0 0 0 56 *Microglia|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1|*Age Related Macular Degeneration|SNPs|Genetic Predisposition to Disease|Alleles|Exon|Serine Endopeptidases|Genotype|Retina|*Signal Transduction|*Transforming Growth Factor|Proteins 459 ARVCF 31827232 Oncogene 2019 10.1038/s41388-019-1133-7 0 8 0 78 TP53 protein, human|*Tumor Suppressor Protein p53|*RNA Splicing|Phosphoproteins|Armadillo Domain Proteins|Alternative Splicing|Cell Adhesion Molecules|mRNA|Velo-Cardio-Facial Syndrome 79 ARVCF 31455759 Transl Psychiatry 2019 PMC6711957 10.1038/s41398-019-0532-4 0 0 0 78 Genome-Wide Association Study|*Schizophrenia|Linkage Disequilibrium|SNPs|Genetic Predisposition to Disease|Gene Frequency|Genotype|Methylenetetrahydrofolate reductase deficiency|Psychotic Disorders|Genetic Variation|*Knowledgebase|Homocystinuria|Muscle Spasticity|Methylenetetrahydrofolate Reductase (NADPH2) 79 ARVCF 31384490 Dermatol Pract Concept 2019 PMC6659599 10.5826/dpc.0903a02 0 0 0 78 Humans|Pemphigus and fogo selvagem|*Compositae|*Pemphigus|Autoantibodies|*Heart|Skin|Desmoplakins|Endemic Diseases|Myocardium|Immunohistochemistry|Antigens|Colombia|South America 79 ARVCF 30814930 Front Cell Neurosci 2019 PMC6381875 10.3389/fncel.2019.00034 0 12 0 78 Male|Mice|Animals|Female|adenylate cyclase 3|*Adenylyl Cyclases|*Mice, Knockout|Phosphopeptides|Proteome|Proteomics|Phosphoproteins|Phosphorylation|Signal Transduction 79 ASTL 31717270 Int J Mol Sci 2019 PMC6887781 10.3390/ijms20225574 2 0 0 52 Plasmodium falciparum|Malaria, Falciparum|Protozoan Proteins|Antimalarials|*Malaria|Plasmodium|HSP70 Heat-Shock Proteins|Protein Binding|artemisinine|Artemisinins|Africa 96 ASTL 31707705 Adv. 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Biol. 2019 10.1007/978-981-13-8719-7_9 0 0 0 52 Allosteric Regulation|Protein Conformation|Proto-Oncogene Proteins c-abl|Protein Kinases|Molecular Dynamics Simulation|Protein Kinase Inhibitors|Signal Transduction|Protein Interaction Maps|Computational Biology|*Lenses|*Lens, Crystalline 96 ASTL 31330173 Biochim Biophys Acta Gen Subj 2019 10.1016/j.bbagen.2019.07.008 2 0 0 52 Allosteric Regulation|Protein Conformation|Molecular Dynamics Simulation|Protein Binding|Signal Transduction|Protein Interaction Maps 96 ASTL 31307198 Neoplasma 2019 PMC6826254 10.4149/neo_2018_181208N933 1 0 0 52 *Paragangliomas|SDHD protein, human|Succinate Dehydrogenase|Pheochromocytoma|*Paragangliomas, Extra-Adrenal|Adrenal Gland Neoplasms|*Genetic Testing|*Head and Neck Neoplasms|Germ-Line Mutation|Neurofibromatosis Type I|Mutations|Genetic Predisposition to Disease|Membrane Proteins|Phenotype|Longitudinal Studies 96 ASTL 31135127 ACS Appl Mater Interfaces 2019 10.1021/acsami.9b02434 0 0 0 52 perovskite|titanium dioxide|*Calcium Compounds|*Oxides|*Titanium|Solar Energy|Electric Power Supplies|*Spectroscopy 96 ASTL 31118423 Nat Commun 2019 PMC6531442 10.1038/s41467-019-10171-7 3 0 0 52 Male|Mice|Animals|Zona Pellucida|Sperm-Ovum Interactions|Zona Pellucida Glycoproteins|*Exocytosis|Fertilization|Sperm|*Plasma Membrane|*Protein Transport|Fertilization in Vitro|Membrane Glycoproteins|*Secretory Vesicles|Cytoplasmic Granules|*Cell Movement 96 ASTL 31103759 World Neurosurg 2019 10.1016/j.wneu.2019.05.061 1 0 0 52 Humans|*Pituitary Neoplasms|*Smell|*Prospective Studies|*Adenoma|*Nose|Neuroendoscopy|Natural Orifice Endoscopic Surgery|Olfaction Disorders|Surgical Flaps|Treatment Outcome|Postoperative Complications|Postoperative Period 96 ASTL 31017783 J Chem Theory Comput 2019 10.1021/acs.jctc.9b00119 3 0 0 52 Allosteric Regulation|Proto-Oncogene Proteins c-abl|Protein Conformation|Simulations, Molecular Dynamics|SH3 Domains|Protein Binding|Core, Catalytic|Binding Sites|Signal Transduction 96 ASTN1 31169361 Chembiochem 2019 10.1002/cbic.201900039 0 0 0 24 Humans|KEAP1 protein, human|*Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Epitopes|*mRNA|*Amino Acid Sequence|Protein Binding|Peptides|Models, Molecular 40 ASTN1 30696770 J. 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Chem. 2019 PMC6433051 10.1074/jbc.RA118.007093 0 0 0 61 Mice|Animals|type I signal peptidase|*Membrane Proteins|*Serine Endopeptidases|Nerve Tissue Proteins|Endoplasmic Reticulum|Neurons|Glycoproteins|Protein Transport|Neurogenesis|Peptide, Signal|Cell Movement|*Membrane|Glycosylation|Microsomes|*Catalysis|Astn1 protein, mouse 47 ASXL3 31638014 Indian Pediatr 2019 0 0 0 48 Child|Humans|*Codon, Nonsense|Developmental Disabilities|Phenotype|Failure to Thrive|Transcription Factors|Mutation|Syndrome|ASXL3 protein, human 49 ASXL3 31558162 J Transl Med 2019 PMC6764142 10.1186/s12967-019-2068-z 2 0 0 48 *Methylation|*Lung Adenocarcinoma|*Transcriptome Analysis|RNA, Long Noncoding|Prognosis|Adenocarcinoma|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Transcriptome|mRNA|Kaplan-Meier Estimate 49 ASXL3 31262251 Genet. Sel. 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Cell 2019 PMC6724508 10.1091/mbc.E18-11-0743 3 2 0 102 Autophagy-Related Proteins|Class III Phosphatidylinositol 3-Kinases|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|Phagosomes|Autophagy|Binding Protein|WD Repeat|Microtubule-Associated Proteins|Membrane Proteins|Protein Interaction Domain|Cell Line|Protein Binding 30 ATG2A 30766969 Contact (Thousand Oaks) 2019 PMC6372110 10.1177/2515256418819936 2 1 0 102 Autophagosomes|Autophagy-Related Proteins|*Membranes|Endoplasmic Reticulum|Membrane Proteins|Binding Protein|Autophagy|Phosphatidylinositol Phosphates|Lipid Metabolism 30 ATG2A 30653393 Autophagy 2019 PMC6526817 10.1080/15548627.2019.1569950 1 2 0 102 *HIV-1|Inhibitor of Apoptosis Proteins|Apoptosis|TNF-Related Apoptosis-Inducing Ligand|Mitochondrial Proteins|CD4-Positive T-Lymphocytes|Intracellular Signaling Peptides and Proteins|*HIV Seropositivity|Carrier Proteins 30 ATG2B 31874152 J. Mol. Biol. 2019 10.1016/j.jmb.2019.12.031 1 0 0 89 *Lipid Droplets|*Autophagy|Autophagy-Related Proteins|Vesicular Transport Proteins|Protein Transport|rab GTP-Binding Proteins|Membrane Proteins|Starvation|Phosphorylation 48 ATG2B 31721365 Genes Cells 2019 10.1111/gtc.12733 0 1 0 89 Humans|*Lipids|Autophagy-Related Proteins|Autophagosomes|Endoplasmic Reticulum|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Autophagy|Membrane Proteins|Phosphatidylinositol Phosphates|*Biological Transport|Membranes|ATG2B protein, human|Vesicular Transport Proteins|ATG18 protein, S cerevisiae 48 ATG2B 31512567 Autophagy 2019 PMC6844525 10.1080/15548627.2019.1666594 1 4 0 89 Animals|*Endoplasmic Reticulum|Autophagy-Related Proteins|*Mitochondrial Membranes|Autophagosomes|*Mitochondria|Autophagy|Carrier Proteins|Membrane Proteins|Phosphatidylinositol Phosphates|Starvation 48 ATG2B 30952800 J. 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Commun. 2019 10.1016/j.bbrc.2019.03.022 2 0 0 95 Female|Mice|Animals|*Lipid Droplets|Mammary Glands, Animal|*Cells, Epithelial|*Endoplasmic Reticulum|Lactation|Milk|Lipogenesis|milk fat globule|Glycolipids|Fatty Acids|Glycoproteins|Cells, Cultured|Lipid Metabolism|RNA, Micro|Triglycerides|Downregulation|Mice, Transgenic|*Cell Count 23 ATL2 30773365 Curr. Biol. 2019 10.1016/j.cub.2019.01.041 25 1 0 95 Animals|*Endoplasmic Reticulum|GTPases|*Carrier Proteins|Autophagy|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Hereditary Sensory and Autonomic Neuropathy Type I 23 atoh7 31696227 Hum. Mol. Genet. 2019 10.1093/hmg/ddz268 2 0 0 163 Humans|*Optic Nerve Hypoplasia|Retinal Ganglion Cells|Optic Nerve Hypoplasia, Bilateral|*Optic Nerve Diseases|Retina|Basic Helix-Loop-Helix Transcription Factors|*Mutations|Helix-Loop-Helix Domain|Eye Abnormalities|Nerve Tissue Proteins|Optic Nerve|Cell Differentiation|Gene Expression Regulation, Developmental|Progenitor Cells|ATOH7 protein, human 174 atoh7 31405994 Development 2019 10.1242/dev.176586 0 2 0 163 Retinal Ganglion Cells|Homeodomain Proteins|Retina|Transcription Factors|Gene Expression Regulation, Developmental|Neural Stem Cells 174 atoh7 30842249 J. Neurosci. 2019 PMC6520504 10.1523/JNEUROSCI.2224-18.2019 2 0 0 163 Mice|Animals|Geniculate Bodies|*Interneurons|*Thalamus|*Retina|Visual Pathways|Retinal Ganglion Cells|Excitatory Postsynaptic Potentials|Neural Inhibition|Synapses|*Signal Transduction 174 atoh7 30733552 Sci Rep 2019 PMC6367446 10.1038/s41598-018-38379-5 5 0 0 163 Humans|Animals|Child|*Zebrafish|Zebrafish Proteins|Coloboma, Ocular|*Transcriptome Profiling|Retina|Morphogenesis|Gene Expression Regulation, Developmental|Optic Disk|In Situ Hybridization|Morpholinos|Transcriptome 174 atoh7 30684501 Vision Res. 2019 10.1016/j.visres.2019.01.008 1 0 0 163 Animals|Humans|*Zebrafish|*Retinal Ganglion Cells|*Nerve, Optic|Zebrafish Proteins|Embryo, Nonmammalian|Early-Onset Glaucoma|Glaucoma|*Retina|Gene Expression Regulation, Developmental|Forkhead Box Transcription Factors|Morpholinos|*Number, Cell|Cell Differentiation|Transcription, Genetic|FOXC1 protein, human|Foxc1b protein, zebrafish 174 ATRNL1 30623622 Ann Lab Med 2019 PMC6340852 10.3343/alm.2019.39.3.299 4 0 0 17 30 AVIL 31575648 Development 2019 PMC6826036 10.1242/dev.181750 0 0 0 115 Transcription Factor|Receptor, trkC|Ganglia, Spinal|Sensory Receptor Cells|Homeodomain Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Core Binding Factor Alpha 3 Subunit|Receptor, trkB|Transcription Factor|Receptor, trkC|Ganglia, Spinal|Sensory Receptor Cells|Homeodomain Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Core Binding Factor Alpha 3 Subunit|Receptor, trkB 1997 AVIL 31852144 Medicine (Baltimore) 2019 PMC6922401 10.1097/MD.0000000000018369 0 0 0 115 *Chlorpheniramine|*Anaphylaxis|*Pharmacovigilance|*Retrospective Studies|Histamine H1 Antagonists|Cetirizine|Urticaria|Loratadine|Terfenadine|Skin Tests|Piperidines|*Databases, Factual 1997 AVIL 31786321 Eur J Pharm Biopharm 2019 10.1016/j.ejpb.2019.11.006 0 0 0 115 *Tablets|Excipients|*Drug Implants|microcrystalline cellulose|Cellulose|Delayed-Action Preparations|Drug Compounding|Solubility|Chemistry, Pharmaceutical|Release, Drug|*Data Compression|*Pressure|*Physical Phenomena 1997 AVIL 31781630 Biomed Res Int 2019 PMC6875361 10.1155/2019/6301915 0 0 0 115 Humans|Animals|*Taste|Chickens|G-Protein-Coupled Receptors|*Dysgeusia|Signal Transduction|Calcium|HEK293 Cells 1997 AVIL 31573786 ACS Appl Mater Interfaces 2019 10.1021/acsami.9b13568 0 0 0 115 *Capsules|Nanofibers|Polyesters|Drug Liberation|Polyvinylpyrrolidone|Drug Compounding|Tissue Scaffolds|Biocompatible Materials|Tissue Engineering|Drug Carriers|Printing, Three-Dimensional|Nanoparticles|Cell Survival 1997 AVIL 31472365 J Pharm Biomed Anal 2019 10.1016/j.jpba.2019.112834 0 0 0 115 *Diet, Reducing|*Drug Contamination|*Dietary Supplements|*Plants, Medicinal|*DNA Sequencing|*Weight Loss|Synephrine|Mass Spectrometry|Caffeine|*Base Sequence|buclizine|Piperazines|Australia 1997 AVIL 31347270 Mol Genet Genomic Med 2019 PMC6732270 10.1002/mgg3.855 1 0 0 115 *Chlorpheniramine|*Long QT Syndrome|ERG1 Potassium Channel|Electrocardiography|*Chromosome Deletion|Genetic Testing|Phenotype|Mutation|Chromosomes 1997 AVIL 31319069 Eur. J. Pharmacol. 2019 10.1016/j.ejphar.2019.172544 0 1 0 115 Rats|Animals|*Brompheniramine|*Analgesia|Anesthetics, Local|*Pain|*Administration, Cutaneous|Mepivacaine|Bupivacaine|*Skin|Anesthesia, Local|*Pain Management|Rats, Sprague-Dawley|Injections, Subcutaneous|*Subcutaneous Tissue|Dose-Response Relationship, Drug 1997 AVIL 31170478 Int J Pharm 2019 10.1016/j.ijpharm.2019.06.002 0 0 0 115 *Lactose|*Spectroscopy, Near-Infrared|*Particle Size|Excipients|Powders|Drug Compounding|microcrystalline cellulose|Cellulose|Chemistry, Pharmaceutical|Technology, Pharmaceutical|Least Squares|Chlorpheniramine|Stearic Acids|Calibration 1997 AVIL 31162248 J. Cardiovasc. Pharmacol. 2019 10.1097/FJC.0000000000000676 0 0 0 115 Female|Humans|Aged|Aged, 80 and over|efonidipine|*Exanthema|*Drug Eruption|*Dihydropyridines|*Nitrophenols|*Organophosphorus Compounds|Itching|Erythema|Antihistamines|Hypertension|Administration, Oral 1997 AVIL 31102232 Environ Sci Pollut Res Int 2019 10.1007/s11356-019-05278-9 0 0 0 115 *Waste Water|*Adsorption|*Chlorpheniramine|*Nitrosamines|Water Purification|graphene oxide|Graphite|Dimethylnitrosamine|Drinking Water|Water Pollutants, Chemical|Disinfection|Magnetite 1997 AVIL 31091109 Org. Lett. 2019 10.1021/acs.orglett.9b01334 1 0 0 115 *Pyridines|*Boronic Acids|Molecular Structure|Catalysis|*Metals 1997 AVIL 31081552 Electrophoresis 2019 10.1002/elps.201900144 0 0 0 115 *Capillary Electrophoresis|Stereoisomerism|Chlorpheniramine 1997 AVIL 31076996 Trop Anim Health Prod 2019 10.1007/s11250-019-01913-2 2 0 0 115 Animals|*Goats|*Pleuropneumonia|Mycoplasma capricolum|Pleuropneumonia, Contagious|Goat Diseases|*Pneumonia, Mycoplasma|Tylosin|Oxytetracycline|Antibiotics|Meloxicam|Enrofloxacin|Anti-Inflammatory Agents|India 1997 BACE2 31856384 Mol Oncol 2019 PMC6998390 10.1002/1878-0261.12623 0 0 0 218 Humans|*Up-Regulation|*Gliomas|*Signal Transduction|*Cell Transformation, Neoplastic|*Tumorigenesis|Glioblastoma Multiforme|NF-kappa B|Epithelial-Mesenchymal Transition|*Transcriptional Activation|Cell Migration|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor 242 BACE2 31838721 Mol. Neurobiol. 2019 PMC7118043 10.1007/s12035-019-01846-9 0 0 0 218 Animals|Mice|Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|NRG2 protein, human|*Nerve Growth Factors|*Proteolysis|ADAM10 Protein|Neuregulin-1|Neurons|*Post-Translational Modifications|Phosphorylation|ErbB Receptors|Hippocampus 242 BACE2 31792732 Funct. Integr. Genomics 2019 10.1007/s10142-019-00728-6 0 8 0 218 Mice|Animals|*Transcriptome|*Sequencing, RNA|*Transcriptome Analysis|*Hippocampus|Protein Interaction Maps|Gene Regulatory Networks|Gene Ontology|*Neurons|Alzheimer Disease|*Whole Exome Sequencing|Alternative Splicing|Computational Biology|Upregulation|DNA Repair 242 BACE2 31661331 Expert Opin Investig Drugs 2019 10.1080/13543784.2019.1683160 4 0 0 218 242 BACE2 31589043 J. Med. Chem. 2019 10.1021/acs.jmedchem.9b01034 1 0 0 218 *Aspartic Acid Endopeptidases|*Amyloid Precursor Protein Secretases|*Amyloid beta-Protein Precursor|Alzheimer Disease|Amyloid beta-Peptides|Brain|Pigmentation 242 BACE2 31545898 ACS Chem Neurosci 2019 10.1021/acschemneuro.9b00348 2 0 0 218 *Amyloid Precursor Protein Secretases|*Aspartic Acid Endopeptidases|*Molecular Dynamics Simulation|*Entropy|Prospective Studies|*Amyloidogenic Proteins|Alzheimer Disease|*Amyloidosis|Binding Sites|2,5-dichloro-4-bromophenol|*Chlorophenols 242 BACE2 31417298 Diabetes Metab Syndr Obes 2019 PMC6602052 10.2147/DMSO.S207019 1 3 0 218 242 BACE2 31415717 Cell. Physiol. Biochem. 2019 10.33594/000000147 1 1 0 218 *Alzheimer Disease|*Amyloid Precursor Protein Secretases|*Amyloid beta-Peptides|*Aspartic Acid Endopeptidases|Amyloid beta-Protein Precursor|Peptide Fragments|Amyloid Plaques|Disease Progression 242 BACE2 31270419 Sci Rep 2019 PMC6610620 10.1038/s41598-019-45896-4 2 1 0 218 Humans|*Apolipoprotein E-4|*Alzheimer Disease|Amyloid beta-Peptides|Amyloid Precursor Protein Secretase|tau Proteins|Peptide Fragments|*Biomarkers|*Amyloidogenic Proteins|Apolipoproteins E|*Amyloidosis|Cognitive Impairment, Mild|SNPs|Genotype 242 BACE2 31021626 J. Med. Chem. 2019 10.1021/acs.jmedchem.9b00309 1 0 0 218 *Aspartic Acid Endopeptidases|*Amyloid Precursor Protein Secretases|*Amyloid beta-Protein Precursor|Alzheimer Disease|PMEL protein, human|gp100 Melanoma Antigen|Drug Design|Melanin 242 BACE2 30945019 Mol. Genet. Genomics 2019 10.1007/s00438-019-01552-0 0 0 0 218 Pregnancy|Female|Humans|*Diabetes Mellitus, Type 2|*Blood Glucose|Gestational Diabetes|Glucose Tolerance Test|Genetic Predisposition|Genetic Association Studies|C Peptide|Receptor, Melatonin, MT2|Insulin|Polymorphism, Single Nucleotide|*Phenotype|Fasting 242 BACE2 30930125 Exp. Eye Res. 2019 10.1016/j.exer.2019.03.012 0 0 0 218 Humans|Mice|Animals|*Amyloid beta-Protein Precursor|*Alzheimer Disease|BACE1 protein, human|Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Corneal dystrophy Avellino type|Corneal Dystrophies, Hereditary|*Cornea|*Fibroblasts|Transforming Growth Factor beta|ADAM10 Protein|Insulin Degrading Enzyme|Autophagy|Proteolysis|MIRN92 microRNA, human|MicroRNAs|Extracellular Matrix Proteins|Western Blot 242 BACE2 30637955 ChemMedChem 2019 PMC6637425 10.1002/cmdc.201800725 0 0 0 218 Humans|Aspartic Acid Endopeptidases|Amyloid Precursor Protein Secretases|*X-Rays|*Structure-Activity Relationship|Amyloid beta-Protein Precursor|Molecular Structure|Ethylamines|Drug Design|*Diabetes Mellitus|Models, Molecular|Crystallography, X-Ray|Stereoisomerism|*Radiography 242 BANK1 31553483 Cancer Sci. 2019 PMC6890443 10.1111/cas.14202 2 0 0 136 *Gastrointestinal Stromal Tumors|Phosphatidylinositol 3-Kinases|Receptor, Platelet-Derived Growth Factor alpha|Proto-Oncogene Proteins c-kit|Imatinib Mesylate|Mutations|*Signal Pathway|*Disease Progression|Oncogenes|Drug Resistance, Neoplasm|Loss of Heterozygosity|Genotype 86 BANK1 31243359 Cell. Mol. Immunol. 2019 10.1038/s41423-019-0254-9 1 3 0 136 Mice|Animals|Tifab protein, human|*TNF Receptor-Associated Factor 6|*Myeloid Differentiation Factor 88|TLR7 protein, human|Toll-Like Receptor 7|*Signal Transduction|*Adaptor Proteins, Signal Transducing|*B Cells|Toll-Like Receptor 9|Interleukin-1 Receptor-Associated Kinases|Ubiquitination|Receptor, Interleukin 1|Membrane Glycoproteins|Immunity, Innate|Myd88 protein, mouse|BANK1 protein, mouse 86 BANK1 31149782 Int J Lab Hematol 2019 10.1111/ijlh.13055 0 1 0 136 Humans|*Hemophilia A|Blood Coagulation Factor Inhibitors|Factor VIII|Gene Frequency|Haplotypes|Alleles|Genotype|Polymorphism, Single Nucleotide|Interleukin-10|*Mitogen-Activated Protein Kinase 9|*Receptors, Colony-Stimulating Factor|Autoantibodies|Risk Factors|China 86 BANK1 31134304 Inflamm. Res. 2019 10.1007/s00011-019-01253-9 0 1 0 136 Humans|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Asian|Polymorphism, Single Nucleotide|Epistasis, Genetic|Adaptor Proteins, Signal Transducing|Membrane Proteins|src-Family Kinases|Genotype|Case-Control Studies|BANK1 protein, human|BLK protein, human 86 BANK1 31101814 Nat Commun 2019 PMC6525203 10.1038/s41467-019-10242-9 3 9 0 136 Humans|Mice|Animals|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|*Lupus Erythematosus, Discoid|Polymorphism, Single Nucleotide|IRF5 protein, human|Interferon Regulatory Factors|Adaptor Proteins, Signal Transducing|Genotype|src-Family Kinases|Epistasis, Genetic|Membrane Proteins|Asian Continental Ancestry Group|Case-Control Studies|B-Lymphocytes|BANK1 protein, human|BLK protein, human|BANK1 protein, mouse 86 BARHL1 31096644 Cells 2019 PMC6562609 10.3390/cells8050458 0 1 0 73 35 BARHL1 30605626 Dev. Biol. 2019 10.1016/j.ydbio.2018.12.025 1 0 0 73 Humans|Animals|Hair Cells, Auditory|*Ear, Inner|Transcription Factor|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|*Epithelium|Gene Expression Regulation, Developmental|Cochlea|Cell Transdifferentiation|*Mammals|Cells, Cultured|POU4F3 protein, human|Transcription Factor Brn-3C|ATOH1 protein, human 35 BARHL2 31036545 Development 2019 10.1242/dev.173112 1 1 0 57 Animals|*T-Cell Factors|*Organizers, Embryonic|*Transcription Factors|LEF1 protein, human|Lymphoid Enhancer-Binding Factor 1|Wnt Proteins|beta Catenin|Xenopus Proteins|Xenopus laevis|*Catenins|Homeodomain Proteins|Signal Transduction|Gene Expression Regulation, Developmental|*Morphogenesis 30 BARHL2 30902784 Gene 2019 10.1016/j.gene.2019.02.102 0 3 0 57 Animals|*Geese|*Introns|MAGI1 protein, human|*Cell Adhesion Molecules, Neuronal|*Breeding|Avian Proteins|Allele Frequency|*Genes, Regulator|SNPs|Reproduction|Cloning, Molecular|RNA, Messenger|Eggs 30 BARX1 31538956 IET Syst Biol 2019 10.1049/iet-syb.2019.0025 0 0 0 95 Humans|*Thyroid Cancer, Papillary|*Down-Regulation|Prospective Studies|*miRNA|Carcinoma, Thyroid|Carcinoma, Papillary|Gene Expression Regulation, Neoplastic|LILRB1 protein, human|*Leukocyte Immunoglobulin-like Receptor B1|Cell Proliferation|Lymphatic Metastasis|*Antigens, CD|Cell Movement|Cell Line, Tumor|Apoptosis|Disease Progression|MIRN7 microRNA, human 100 BARX1 31492950 Sci Rep 2019 PMC6731288 10.1038/s41598-019-49116-x 0 2 0 95 Humans|Mice|Animals|*Genes, Homeobox|*Tooth|Homeodomain Proteins|MSX1 Transcription Factor|Transcription Factors|Tooth Germ|Mesoderm|Morphogenesis|Gene Expression Regulation, Developmental|*Mammals 100 BARX1 31340933 Development 2019 10.1242/dev.175042 0 2 0 95 Humans|*Genes, Homeobox|Homeodomain Proteins|Body Patterning|Facial Bones|Gene Expression Regulation, Developmental|Transcription Factors|Histone Acetyltransferases|Embryo, Mammalian|*Gene Expression|Mutation 100 BARX1 31048564 J Neurogastroenterol Motil 2019 PMC6657930 10.5056/jnm18183 0 1 0 95 Humans|Quality of Life|*Gastroesophageal Reflux|Esophageal Neoplasms|Polymorphism, Single Nucleotide|Adenocarcinoma|Genotype|Case-Control Studies|Risk Factors|BARX1 protein, human|Transcription Factors|Homeodomain Proteins|ADAMTS17 protein, human|ADAMTS Proteins 100 BARX1 31014063 Minerva Stomatol 2019 10.23736/S0026-4970.19.04166-9 0 0 0 95 *Odontoma|*Pilot Projects|Odontogenic Tumors|Jaw Neoplasms|*Neural Plate|*Ectoderm|*Biomarkers|*Cell Lines 100 BARX1 30947707 BMC Cancer 2019 PMC6449919 10.1186/s12885-019-5501-z 1 0 0 95 Cats|Animals|Dogs|*Soft Tissue Neoplasms|*Sarcoma|Injection Site Reaction|Cat Diseases|*Research Design|*Connective Tissue Diseases|*Diagnostic Tests, Routine|RNA, Messenger 100 BARX1 30923412 Acta Histochem Cytochem 2019 PMC6434314 10.1267/ahc.18038 0 36 0 95 Animals|Chick Embryo|*Wnt Signaling Pathway|*Maxilla|Morphogenesis|Wnt Proteins|Gene Expression Regulation, Developmental|Cleft Palate|Transcription Factors|Cleft Lip|Face|Downregulation 100 BARX1 30778087 Sci Rep 2019 PMC6379364 10.1038/s41598-018-37489-4 1 1 0 95 Adult|Humans|Proteomics|Stem Cell|Mesenchymal Stem Cell|Cell Differentiation|Osteogenesis|Cell Aging|Odontogenesis|Cell Proliferation|Adipogenesis|Cells, Cultured|Adult Stem Cells|*Aging 100 BARX1 30679499 Sci Rep 2019 PMC6346038 10.1038/s41598-018-36413-0 0 0 0 95 Animals|Prospective Studies|CDX1 protein, human|Homeodomain Proteins|*Stomach|Transcription Factors|Gastric Gland|Endoderm|Mesenchyme|SOX2 protein, human|SOXB1 Transcription Factors|CDX2 Transcription Factor|Gene Expression Regulation, Developmental|Cell Differentiation|BMP4 protein, human|Bone Morphogenetic Protein 4|Vertebrates|*Viscera 100 BASP1 31733664 Int. Rev. Neurobiol. 2019 PMC6939615 10.1016/bs.irn.2019.10.017 2 2 0 707 Humans|Animals|Mice|*Alzheimer Disease|Amyloid beta-Peptides|*C57BL Mice|Presenilin-1|Amyloid beta Precursor Protein|tau Proteins|*Disease Models, Animal|Plaque, Amyloid|Mice, Transgenic|Brain|Maze Learning|Memory Disorders|Memory, Spatial|Hippocampus|Phosphorylation|Amygdala|*Alcohol Drinking|ATP5D protein, human 136 BASP1 31202182 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2019 10.1016/j.jchromb.2019.06.005 0 0 0 707 Animals|Mice|*Alzheimer Disease|*Hyperhomocysteinemia|*Proteome|*Vitamin B Complex|*Chromatography, Liquid|*Tandem Mass Spectrometry|*Disease Models, Animal|Presenilin-1|*Brain|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|Mice, Transgenic|*Diet|Proteomics 136 BASP1 31167803 Life Sci Alliance 2019 PMC6555901 10.26508/lsa.201800287 1 1 0 707 Animals|Mice|*Taste|*Cell Differentiation|Nerve Tissue Proteins|*Taste Buds|Cytoskeletal Proteins|Calmodulin-Binding Proteins|Membrane Proteins|WT1 Proteins|Repressor Proteins|Promoter Regions, Genetic|*Genes, Regulator|Cell Line|WT1 protein, mouse 136 BASP1 31146115 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.108985 1 1 0 707 Humans|*Neuroma, Acoustic|Proteomics|Quality of Life|Neoplasm Recurrence, Local|Cerebellopontine Angle|TYRP1 protein, human|*Membrane Glycoproteins|Retrospective Studies|Postoperative Complications 136 BASP1 31058089 Front Oncol 2019 PMC6478813 10.3389/fonc.2019.00289 2 10 0 707 MARCKS protein, human|Myristoylated Alanine-Rich C Kinase Substrate|Nerve Tissue Proteins|Membrane Proteins|Calmodulin-Binding Proteins|Intracellular Signaling Peptides and Proteins|Cell Nucleus|*Signal Transduction|Calmodulin|*Oncogenesis|Cell Membrane|Repressor Proteins|WT1 Proteins|Cytoskeleton|Gene Expression Regulation|Cell Transformation, Neoplastic|Phospholipids|Promoter Regions, Genetic 136 BASP1 30982764 EBioMedicine 2019 PMC6557784 10.1016/j.ebiom.2019.04.008 4 1 0 707 *Proteomics|*Prognosis|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Chromatography, Liquid|Biomarkers, Tumor|Tandem Mass Spectrometry|Kaplan-Meier Estimate|*Transcription Factors|Brain 136 BASP1 30917169 PLoS ONE 2019 PMC6436751 10.1371/journal.pone.0214078 5 4 0 707 Male|Humans|Mice|Animals|*Prostate|*Genistein|*Duration of Therapy|Prostate Cancer|*Cell Motility|Matrix Metalloproteinase 2|Cell Line, Tumor|Cell Proliferation|*Biomarkers 136 Bbx 31883436 Plant Biotechnol. J. 2019 PMC7292546 10.1111/pbi.13322 1 0 0 145 *Chrysanthemum|Gene Expression Regulation, Plant|Flowers|Arabidopsis|Photoperiod|Plant Proteins|Diurnal Rhythm 73 Bbx 31851942 Cell Rep 2019 PMC7030938 10.1016/j.celrep.2019.11.051 2 0 0 145 73 Bbx 31780719 Sci Rep 2019 PMC6882830 10.1038/s41598-019-54166-2 0 3 0 145 *Malus|cyanidin|*Anthocyanins|Fruit|Gene Expression Regulation, Plant|Transcription Factors|Plant Proteins|Genes, Plant|Promoter Regions, Genetic|Plants, Genetically Modified 73 Bbx 31664720 New Phytol. 2019 10.1111/nph.16296 1 0 0 145 *Light Signal Transduction|Arabidopsis Proteins|Arabidopsis|Hypocotyl|Gene Expression Regulation, Plant|Seedling|E3 Ubiquitin Ligase|Basic-Leucine Zipper Transcription Factors|Nuclear Proteins|Darkness|Signal Transduction|Morphogenesis|Ubiquitination|COP10 protein, Arabidopsis|Ubiquitin-Conjugating Enzymes|HY5 protein, Arabidopsis 73 Bbx 31655346 Plant Physiol. Biochem. 2019 10.1016/j.plaphy.2019.10.019 1 0 0 145 *Arabidopsis|*Chrysanthemum|SH2D1B protein, human|Transcription Factors|Gene Expression Regulation, Plant|Arabidopsis Proteins|Flowers|MADS Domain Proteins|Plant Proteins|Genes, Plant|Plant Leaves|Plants, Genetically Modified|Photoperiod|Transcriptional Activation 73 Bbx 31550006 Plant Cell Physiol. 2019 10.1093/pcp/pcz185 1 1 0 145 *Malus|*Hypocotyl|*Anthocyanins|Gene Expression Regulation, Plant|Arabidopsis|Plant Proteins|Transcription Factors|Plants, Genetically Modified|Plant Development|Promoter Regions, Genetic|*Food Hypersensitivity 73 Bbx 31444818 Plant J. 2019 10.1111/tpj.14510 1 14 0 145 *Pyrus|*Anthocyanins|*Fruit|*Hypocotyl|Gene Expression Regulation, Plant|TYRP1 protein, human|Plant Proteins|Transcription Factors|*Membrane Glycoproteins|Pigmentation|Arabidopsis|Light 73 Bbx 31191575 Front Plant Sci 2019 PMC6546890 10.3389/fpls.2019.00651 1 0 0 145 Arabidopsis|Arabidopsis Proteins|Gene Expression Regulation, Plant|Flowers|Transcription Factors|DNA-Binding Proteins|Photoperiod|Plant Proteins|Plants, Genetically Modified|Gene Expression Regulation, Developmental 73 Bbx 31182022 BMC Plant Biol. 2019 PMC6558717 10.1186/s12870-019-1851-6 4 0 0 145 *Dendrobium|Gene Expression Regulation, Plant|Genes, Plant|Plant Proteins|Oxylipins|Plant Growth Regulators|Multigene Family|Gene Expression Profiling|Transcription Factors|Stress, Physiological|Plant Development|Chromosome Mapping|Phylogeny 73 Bbx 31084872 Plant Sci. 2019 10.1016/j.plantsci.2019.04.017 1 2 0 145 73 BCAM 31841878 Neural Netw 2019 10.1016/j.neunet.2019.11.021 0 0 0 650 *Neural Networks, Computer|Models, Neurological|Action Potentials|Algorithms|Neurons|Normal Distribution|Brain|Memory 232 BCAM 31841635 ACS Synth Biol 2019 10.1021/acssynbio.9b00292 0 0 0 650 valerolactam|*Lactams|*Biosensor|Pseudomonas putida|Caprolactam 232 BCAM 31756339 J. Theor. Biol. 2019 10.1016/j.jtbi.2019.110088 0 0 0 650 *Glioma|Brain Neoplasms|Diffusion Tensor Imaging|*Neoplastic Processes|Cell Migration|Anisotropy|Computer Simulation|Models, Biological|Mathematical Model|*Nervous Tissue 232 BCORL1 31772466 Contemp Clin Dent 2019 PMC6868610 10.4103/ccd.ccd_611_18 0 0 0 82 *Cross-Sectional Studies|*Dermatoglyphics|*Dental Caries|India|Case-Control Studies 58 BCORL1 31771970 J. Clin. Pathol. 2019 10.1136/jclinpath-2019-206132 0 0 0 82 *Myelodysplastic Syndrome|*Mutations|*Prognosis|Epigenesis, Genetic|DNA Methylation|DNA-Binding Proteins|*Epigenetic|Repressor Proteins 58 BCORL1 31471323 Blood Adv 2019 PMC6737409 10.1182/bloodadvances.2018028522 2 3 0 82 RNF2 protein, human|*Polycomb Repressive Complex 1|KDM2A protein, human|*Jumonji Domain-Containing Histone Demethylases|*F-Box Proteins|CpG Islands|*Genes, Tumor Suppressor|Histones|*T-Cell Leukemias|Cell Differentiation|Protein Domains|Zinc Finger|T-Lymphocytes 58 BCORL1 31104347 Brain Pathol. 2019 PMC6859193 10.1111/bpa.12747 2 0 0 82 Child|Humans|Child, Preschool|Homozygote|Sequence Deletion|*Neoplasms, Neuroepithelial|*Exon|OLIG2 protein, human|Oligodendrocyte Transcription Factor 2|Glioma|Proto-Oncogene Proteins|Repressor Proteins|*Genomics|Brain Neoplasms|Central Nervous System Neoplasms|EP300 protein, human|E1A-Associated p300 Protein|*Clinical Pathology|SMARCA2 protein, human|*Transcription Factors|Biomarkers, Tumor 58 BCORL1 30941876 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61118 0 0 0 82 Humans|*Intellectual Disability|*Genes, X-Linked|Phenotypes|Facies|Genetic Association Studies|*Transcription Factors|Pedigree|Abnormalities, Multiple|Exome|Sequencing, Whole Exome|Alleles|Mutation|Genotype|*Problem Behavior|High-Throughput Nucleotide Sequencing|*Musculoskeletal Abnormalities|Syndrome|Co-Repressor Proteins 58 BCORL1 30789359 Am. J. Surg. Pathol. 2019 PMC6764763 10.1097/PAS.0000000000001215 1 0 0 82 Humans|Female|*Sarcoma, Endometrial Stromal|In Situ Hybridization, Fluorescence|Immunohistochemistry|Gene Rearrangement|Endometrial Neoplasms|YWHAE protein, human|14-3-3 Proteins|*Sarcoma|Oncogene Proteins, Fusion|Biomarkers, Tumor|Repressor Proteins|*Soft Tissue Neoplasms|Transcription Factors|Whole Exome Sequencing|Phenotype|Genes, cdc 58 BEND3 31715260 Cell. Signal. 2019 10.1016/j.cellsig.2019.109467 1 6 0 121 Blood-Brain Barrier|Brain Ischemia|Brain|Capillary Permeability|Infarction, Middle Cerebral Artery|Neuroprotective Agents|Stroke|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Zonula Occludens-1 Protein|Reperfusion Injury|Endothelial Cells|MAP Kinase Signaling System|CRF receptor type 1|Receptors, Corticotropin-Releasing Hormone 93 BEND3 31271645 FEBS Lett. 2019 10.1002/1873-3468.13526 0 2 0 121 Animals|Mice|*Claudin-5|*Down-Regulation|*Malaria, Cerebral|Endothelial Cells|Transcriptional Regulator ERG|*Brain|Tight Junctions|Blood-Brain Barrier|Cells, Cultured|Promoter Regions, Genetic|Permeability|*Endothelium|*Experimental Model 93 BEND3 31045510 Biorheology 2019 10.3233/BIR-180204 1 0 0 121 *Glycocalyx|*Microscopy|Endothelium, Vascular|Endothelial Cells|Heparitin Sulfate|Hemodynamics|Cells, Cultured 93 BEND3 31026065 J. Cell. Physiol. 2019 10.1002/jcp.28653 2 3 0 121 United States|Animals|Mice|*Acute Stroke|*Brain Ischemia|*Orosomucoid|PLAT protein, human|Tissue Plasminogen Activator|*Protein, Acute-Phase|Middle Cerebral Artery Occlusion|Blood-Brain Barrier|*Disease Models, Animal|Brain|Apoptosis|Oxidative Stress|Oxygen|Glucose 93 BEND3 30961553 BMC Cancer 2019 PMC6454625 10.1186/s12885-019-5554-z 4 0 0 121 Humans|*Transcriptome|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Liver Neoplasms|Biomarkers, Tumor|Kaplan-Meier Estimate|Lung Neoplasms|Brain Neoplasms 93 BEND3 30867725 Exp Ther Med 2019 PMC6396002 10.3892/etm.2019.7186 1 2 0 121 *Blood-Brain Barrier|*Epidermal Growth Factor|Claudin-5|Tight Junctions|Permeability|Zonula Occludens-1 Protein|Glucose|Endothelial Cells|Stroke|Oxygen|Reperfusion Injury|*Biological Transport|Brain Ischemia 93 BEND3 30828041 Biol. Pharm. Bull. 2019 10.1248/bpb.b18-00628 1 2 0 121 Animals|Mice|*Endoplasmic Reticulum Stress|*Vascular Endothelial Growth Factor A|*Vascular Endothelial Growth Factor B|Endothelial Cells|*Apoptosis|Transcription Factor CHOP|Caspase 12|Reperfusion Injury|Middle Cerebral Artery Occlusion|In Situ Nick-End Labeling|XBP1 protein, human|X-Box Binding Protein 1|*Reperfusion|ERN1 protein, human|Protein-Serine-Threonine Kinases|Endoribonucleases|Brain Ischemia|Endoplasmic Reticulum 93 BEND3 30687773 Bio Protoc 2019 PMC6343665 10.21769/BioProtoc.3128 7 0 0 121 Animals|Mice|*Membrane Potential, Mitochondrial|5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine|*Fluorescent Dyes|Reproducibility of Results|Endothelial Cells|Carbocyanines|Benzimidazoles|Mitochondria|Flow Cytometry|*Cations 93 BEND3 30671696 Cell. Mol. Neurobiol. 2019 10.1007/s10571-019-00653-z 2 0 0 121 Animals|Rats|Humans|Adolescent|*Alzheimer Disease|Endothelial Cells|HEK293 Cells|Induced Pluripotent Stem Cells|Cell Culture|Organoids|Brain|*Drug Development|Astrocytes 93 BHLHA15 31276933 Neoplasia 2019 PMC6611983 10.1016/j.neo.2019.06.003 0 4 0 200 66 BHLHA15 31187185 Virchows Arch. 2019 10.1007/s00428-019-02600-1 0 0 0 200 66 BLID 31793001 Am J Community Psychol 2019 10.1002/ajcp.12404 0 0 0 49 Adult|Humans|*Housing|Cross-Sectional Studies|*Homelessness|Mental Disorders|Community Mental Health Services|Community Integration|Case Management|Social Problems|Europe 187 BLID 31791966 BMJ Open 2019 PMC6924844 10.1136/bmjopen-2019-033237 0 0 0 49 Humans|*Prevalence|*Homelessness|Europe|*Social Problems|Surveys and Questionnaires 187 BLID 31324803 Nat Commun 2019 PMC6642116 10.1038/s41467-019-11173-1 2 0 0 49 Humans|hepatitis B virus X protein|*Trans-Activators|BCL2L1 protein, human|bcl-XL Protein|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Hepatitis B virus|Protein Binding|Amino Acid Sequence|Hydrophobic and Hydrophilic Interactions|Peptides 187 BLID 31173853 Cancer Lett. 2019 10.1016/j.canlet.2019.05.035 14 1 0 49 *Stomach Neoplasms|miRNAs|Exosomes|Cell Proliferation|Drug Resistance, Neoplasm|Doxorubicin|Cisplatin|Antineoplastic Agents|Downregulation|*Tumorigenesis|Apoptosis|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Cycle|Transfection 187 BMP2K 30982749 Cell Chem Biol 2019 PMC6634314 10.1016/j.chembiol.2019.02.021 5 0 0 204 *Cysteine|Protein Kinase Inhibitors|Protein Kinases|Drug Design|Lysine 23 BMP3 31816287 Clin. Chim. Acta 2019 10.1016/j.cca.2019.12.001 0 2 0 274 *Occult Blood|*Colorectal Neoplasms|*Early Detection of Cancer|*Screening|Feces|Biomarkers, Tumor|Sensitivity and Specificity|DNA Methylation|*Research Design|DNA 234 BMP3 31816047 Hum. Mol. Genet. 2019 PMC7068119 10.1093/hmg/ddz294 2 0 0 274 Humans|*Retinal Detachment|Genome-Wide Association Study|Myopia|Vitrectomy|Visual Acuity|Glaucoma|Risk Factors|DLG5 protein, human|Membrane Proteins|Tumor Suppressor Proteins|TRIM29 protein, human|DNA-Binding Proteins|Transcription Factors 234 BMP3 31764091 Am. J. Gastroenterol. 2019 PMC6903367 10.14309/ajg.0000000000000445 2 2 0 274 *Early Detection of Cancer|*Occult Blood|*Colorectal Neoplasms|Colonoscopy|Adenomas|Feces|Mass Screening|DNA, Neoplasm|Sensitivity and Specificity 234 BMP3 31680186 Fish Physiol. Biochem. 2019 10.1007/s10695-019-00721-7 0 0 0 274 Animals|*Phylogeny|Carps|Fish Proteins|Sequence Alignment|Sequences, Amino Acid|TYRP1 protein, human|*Membrane Glycoproteins|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|BMP6 protein, human|Bone Morphogenetic Protein 6|BMP4 protein, human|Bone Morphogenetic Protein 4|Bone Morphogenetic Proteins|Danio rerio|BMP2 protein, human|*Morphogenesis|mRNA 234 BMP3 31665064 J. Exp. Clin. Cancer Res. 2019 PMC6819484 10.1186/s13046-019-1435-1 0 9 0 274 Humans|*MAP Kinase Signaling System|SMAD2 protein, human|*Smad2 Protein|Colorectal Cancer|*Colon|HCT116 Cells|BMP3 protein, human|*Bone Morphogenetic Protein 3|*Tumorigenesis|*Cell Transformation, Neoplastic|Cell Movement|Gene Expression Regulation, Neoplastic|Signal Transduction|DNA Methylation|Cell Proliferation|Cell Line, Tumor|Neoplasm Transplantation 234 BMP3 31639434 Gene 2019 10.1016/j.gene.2019.144167 0 8 0 274 Humans|*Bile Acids|*Bilirubin|Ursodeoxycholic Acid|*Liver Diseases|Cholestasis|Lithocholic Acid|*Osteoporosis|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Up-Regulation|Liver|Downregulation|Osteoblasts|Osteocalcin|Apoptosis|*Genetic Profile|recombinant human bone morphogenetic protein-2|Transforming Growth Factor beta 234 BMP3 31602277 J Cancer 2019 PMC6775613 10.7150/jca.34944 1 3 0 274 234 BMP3 31524275 Oncol. Rep. 2019 PMC6718975 10.3892/or.2019.7275 6 9 0 274 Humans|Neoplasm Recurrence, Local|BMP7 protein, human|*Bone Morphogenetic Protein 7|*Bone Morphogenetic Protein|*Estrogens|BMPR1B protein, human|Bone Morphogenetic Protein Receptors, Type I|BMP6 protein, human|Bone Morphogenetic Protein 6|BMPR1A protein, human|Bone Morphogenetic Protein 4|Bone Morphogenetic Protein Receptors, Type II 234 BMP3 31456088 J. Cancer Res. Clin. Oncol. 2019 10.1007/s00432-019-02992-2 0 2 0 274 *Colorectal Neoplasms|*Feces|Cancer Screening|Colonic Polyps|Colonoscopy|*Screening|Biomarkers, Tumor|DNA Methylation|Gene Expression Regulation, Neoplastic|*Genetic Markers|DNA|China 234 BMP3 31455201 Curr Stem Cell Res Ther 2019 PMC7040507 10.2174/1574888X14666190628103528 1 0 0 274 Humans|Mice|Rats|Rabbits|Animals|*Mesenchymal Stem Cells|*Spinal Fusion|*Cytokines|*Bone Morphogenetic Protein|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|BMP2 protein, human|Transforming Growth Factor beta|*Intervertebral Disk|BMP7 protein, human|Bone Morphogenetic Protein 7|Osteogenesis|Osteoblasts|*Bone|Cell Differentiation|BMP4 protein, human|Bone Morphogenetic Protein 4|noggin protein 234 BMP8B 31524275 Oncol. Rep. 2019 PMC6718975 10.3892/or.2019.7275 6 9 0 137 Humans|Neoplasm Recurrence, Local|BMP7 protein, human|*Bone Morphogenetic Protein 7|*Bone Morphogenetic Protein|*Estrogens|BMPR1B protein, human|Bone Morphogenetic Protein Receptors, Type I|BMP6 protein, human|Bone Morphogenetic Protein 6|BMPR1A protein, human|Bone Morphogenetic Protein 4|Bone Morphogenetic Protein Receptors, Type II 74 BMP8B 31096638 Cells 2019 PMC6562647 10.3390/cells8050457 3 0 0 137 Humans|Mice|Animals|*Hepatocytes|Nonalcoholic Fatty Liver Disease|Liver|Lipogenesis|*Inflammation|Triglycerides|Acids, Fatty|BMP8B protein, human|*Bone Morphogenetic Proteins|Obesity|Mice, Inbred C57BL|Hep G2 Cells|Diet 74 BMP8B 30976490 Acta Pharm Sin B 2019 PMC6438825 10.1016/j.apsb.2018.09.007 2 0 0 137 Humans|Adult|Diabetes Mellitus, Type 2|Adipose Tissue, Brown|Thermogenesis|*Obesity|Uncoupling Protein 1|Adipose Tissue, White|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Energy Metabolism|Transcription Factors|Cold Temperature 74 BMP8B 30741078 Ultrastruct Pathol 2019 10.1080/01913123.2019.1572256 0 0 0 137 Rats|Male|Animals|*Mesenchymal Stem Cells|*Cisplatin|*Testis|Mesenchymal Stem Cell Transplantation|Bone Marrow Cells|Cell Differentiation|Stem Cell|Apoptosis|Oxidative Stress 74 BMP8B 30609449 Obes Rev 2019 PMC6447448 10.1111/obr.12822 7 0 0 137 recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|BMP7 protein, human|Bone Morphogenetic Protein 7|Adipogenesis|Bone Morphogenetic Proteins|BMP4 protein, human|Bone Morphogenetic Protein 4|Transforming Growth Factor beta|BMP2 protein, human|*Signal Transduction|*Gene Expression Regulation|Cell Differentiation|Adipose Tissue, Brown|Growth Differentiation Factors|Bone Formation 74 BMPER 31659097 Cancer Genomics Proteomics 2019 PMC6885362 10.21873/cgp.20146 1 1 0 173 Humans|*Apigenin|*Transcriptome|*Tumor Necrosis Factor-alpha|*Transcriptome Analysis|NF-kappa B|Triple-Negative Breast Cancer|Cell Line, Tumor|Signal Transduction|Gene Expression Regulation, Neoplastic|NF-kappa B kinase|Protein-Serine-Threonine Kinases|Chemokine, CCL5 86 BMPER 31130878 Front Physiol 2019 PMC6509393 10.3389/fphys.2019.00537 0 1 0 173 Animals|Bombyx|Insect Proteins|System, Circadian Clock|Circadian Rhythm|Cell Line 86 BMPER 31064821 Biosci. Rep. 2019 PMC6527926 10.1042/BSR20182320 0 0 0 173 Humans|Animals|*Endoglin|*Telangiectasia, Hereditary Hemorrhagic|*Zebrafish|Activin Receptors, Type II|*Signal Transduction|*Protein Binding|Endothelial Cells|*Cell Differentiation|*Receptors, Growth Factor|*Morphogenesis 86 BMPER 30890123 BMC Genomics 2019 PMC6425649 10.1186/s12864-019-5531-6 1 0 0 173 Humans|Dogs|Animals|Osteosarcoma|Bone Neoplasms|Dog Diseases|DNA Copy Number Variations|*Multifactorial Inheritance|Genetic Predisposition to Disease|Disease Models, Animal 86 BMPER 30800678 Biomed Res Int 2019 PMC6360565 10.1155/2019/8078139 1 0 0 173 Humans|*Ureteroscopy|*Prognosis|*Lithotripsy|*Urinary Tract Infections|*Sepsis|*Bone Morphogenetic Protein|*Endothelial Progenitor Cells|Logistic Regression|Risk Factors|Ureteral Obstruction|Postoperative Period|Receiver Operating Characteristic|BMPER protein, human|Carrier Proteins 86 bnc1 31877923 Genes (Basel) 2019 PMC7017422 10.3390/genes11010014 1 0 0 179 *DNA Methylation|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|CpG Islands|Cancer Biomarkers|Promoter Regions, Genetic|Epigenesis, Genetic|Prognosis|Cell Free DNA|Pancreas|Chronic Pancreatitis 94 bnc1 31836902 Biol. Reprod. 2019 PMC7305688 10.1093/biolre/ioz222 0 1 0 179 Male|Mice|Animals|*Spermatogonia|*Progenitor Cells|*Receptor Protein-Tyrosine Kinases|EPHB2 protein, human|*EphB2-Tyrosine Kinase|Spermatogenesis|Cultured Cells|Testis|Stem Cell Transplantation|Signal Transduction|Cell Line|Stem Cells, Somatic|Cell Proliferation|Bnc1 protein, mouse|DNA-Binding Proteins|Transcription Factors 94 bnc1 31767620 Development 2019 PMC6955213 10.1242/dev.174441 3 0 0 179 Humans|Mice|Animals|*Pluripotent Stem Cell|*Epicardium|Cell Differentiation|Cell Lineage|Myocytes, Smooth Muscle|Transcription Factors|Myocytes, Cardiac|Fibroblasts|WT1 Proteins|TCF21 protein, human|Basic Helix-Loop-Helix Transcription Factors|BNC1 protein, human|DNA-Binding Proteins|Bnc1 protein, mouse 94 bnc1 31625664 Angew. Chem. Int. Ed. Engl. 2019 PMC6973171 10.1002/anie.201910704 1 0 0 179 *Artificial Sweeteners|*Stereoisomerism|neotame|*Dipeptides|N-(N-(3-(3-hydroxy-4-methoxyphenyl) propyl)-alpha-aspartyl)-L-phenylalanine 1-methyl ester|ethylenediamine|Ethylenediamines|Aspartic Acid|Biocatalysis|Phyllobacteriaceae|Fumarates|*Lyases 94 bnc1 31580513 Mol. Microbiol. 2019 10.1111/mmi.14399 1 1 0 179 *Oxidase|*Phyllobacteriaceae|Edetic Acid|Bioremediation|ethylenediamine|Ethylenediamines|isoalloxazine|Flavins|Mixed Function Oxygenases|Oxidation-Reduction|Bacteria|Bacterial Proteins 94 bnc1 31488892 Eur. J. Hum. Genet. 2019 PMC6906293 10.1038/s41431-019-0495-1 1 0 0 179 Humans|Female|*Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|*Phenotype|*Gynecologic Diseases|Endometriosis|Polymorphism, Single Nucleotide|Genotype|Carcinoma, Ovarian Epithelial|Endometrial Neoplasms|Uterine Fibroid|Ovarian Cancer|Model, Logistic 94 bnc1 31313401 Mol. Carcinog. 2019 PMC6721979 10.1002/mc.23084 0 6 0 179 Mice|Animals|*Receptor, Cholecystokinin B|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|Carcinoma in Situ|Genes, ras|Mice, Transgenic|Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic|Disease Progression|Cell Line, Tumor|YF 476|Phenylurea Compounds|Benzodiazepinones|*Chemoprevention 94 bnc1 31065688 J Mol Cell Biol 2019 PMC7052986 10.1093/jmcb/mjz035 1 1 0 179 Humans|Male|Mice|Animals|*Testis|*Aging, Premature|*Spermatogenesis|Transcription Factor IID|TATA-Binding Protein Associated Factors|Azoospermia|Transcription Factors|Spermatozoa|DNA-Binding Proteins|Transcription, Genetic|Fertility|BNC1 protein, human|Ybx2 protein, mouse|RNA-Binding Proteins|TAF7L protein, mouse|Odf1 protein, mouse|Heat-Shock Proteins|Bnc1 protein, mouse 94 bnc1 30953539 Clin Epigenetics 2019 PMC6451253 10.1186/s13148-019-0650-0 8 3 0 179 Humans|Early Detection of Cancer|*Promoter Regions, Genetic|*Pancreas Cancer|DNA Methylation|ADAMTS1 protein, human|*ADAMTS1 Protein|Epigenesis, Genetic|Biomarkers, Tumor|DNA-Binding Proteins|Transcription Factors|BNC1 protein, human 94 bnc1 30689869 Hum. Reprod. 2019 PMC6389867 10.1093/humrep/dey389 2 0 0 179 Humans|Female|*Primary Ovarian Insufficiency|*Menopause, Premature|DNA Copy Number Variations|Ovary|Comparative Genomic Hybridization|Mutation|Cohort Studies|Phenotype 94 bnc1 30678915 Mater Sci Eng C Mater Biol Appl 2019 10.1016/j.msec.2018.12.016 0 0 0 179 Swine|Animals|*Gluconacetobacter xylinus|*Cellulose|Prostheses and Implants 94 BNC2 31453699 J Phys Chem A 2019 10.1021/acs.jpca.9b05315 0 0 0 85 *Graphite|*Nanotubes, Carbon|Models, Chemical|Models, Molecular|Boron|Thermodynamics|*Catalysis 77 BNC2 31400656 Forensic Sci Int Genet 2019 10.1016/j.fsigen.2019.07.012 0 0 0 85 Humans|Male|Female|*B-DNA|Hair Color|*Freckle|Eye Color|Receptor, Melanocortin, Type 1|Phenotype|Genotype|SNPs|Skin Pigmentation|DNA|Models, Genetic|Interferon Regulatory Factors|Logistic Models|Monophenol Monooxygenase|Membrane Transport Proteins|Antiporters|Poland 77 BNC2 31365516 Spine 2019 10.1097/BRS.0000000000003179 1 0 0 85 Humans|Adult|Adolescent|*Scoliosis|*Intervertebral Disc Degeneration|Case-Control Studies|Single Nucleotide Polymorphisms|Genetic Association Studies|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Homeodomain Proteins|Genotype|*Kyphosis|Transcription Factors 77 BNC2 31051115 Am. J. Hum. Genet. 2019 PMC6506863 10.1016/j.ajhg.2019.03.023 2 0 0 85 Male|Pregnancy|Humans|Female|*Urethral Diseases|Urethral Obstruction|Urinary Bladder Neck Obstruction|Fetal Diseases|Ultrasonography, Prenatal|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Bladder|Urethra|Gestational Age|Retrospective Studies|BNC2 protein, human|DNA-Binding Proteins 77 BNC2 30895612 Dev. Growth Differ. 2019 PMC6850407 10.1111/dgd.12601 2 0 0 85 *Genes, Homeobox|homeobox protein HOXA13|*Homeodomain Proteins|Transcription Factors|Limb|Gene Expression Regulation, Developmental|Body Patterning|*Chondrogenesis|Binding Sites|*Embryonic Development|In Situ Hybridization|DNA Chip|Sequences, Conserved 77 BNC2 30709872 Cancer Res. 2019 10.1158/0008-5472.CAN-18-3938 0 0 0 85 Humans|Female|Genome-Wide Association Study|Epithelial Ovarian Cancer|Genetic Susceptibility|Neoplasms, Glandular and Epithelial|Ovarian Neoplasms|Polymorphism, Single Nucleotide|Genetic Loci|Case-Control Studies|Risk Factors 77 BRAC1 31714881 Clin. Chem. Lab. Med. 2019 10.1515/cclm-2019-0693 1 0 0 0 Humans|Male|Middle Aged|Aged|kallikrein-related peptidase 3, human|*Prostate-Specific Antigen|Neoplasm Recurrence, Local|*Prostate Cancer|Kallikreins|Prostate|Biopsy|Biomarkers, Tumor|Antigens, Neoplasm|Prognosis|MDV 3100|Phenylthiohydantoin|ROC Curve|abiraterone|Androstenes|Specificity 40 BRAC1 31697643 Aging (Albany NY) 2019 PMC6874460 10.18632/aging.102402 0 3 0 0 *Esophageal Squamous Cell Carcinoma|*Atorvastatin|*Esophageal Neoplasms|*Proteome|Carcinoma, Squamous Cell|Signal Pathways|Gene Expression Regulation, Neoplastic|Cell Proliferation|Down-Regulation|Cell Line, Tumor 40 BRAC1 30957202 Anal Bioanal Chem 2019 10.1007/s00216-019-01739-9 1 0 0 0 *B-DNA|*Biosensors|ferrocene|Metallocenes|Nucleic Acid Hybridization|Electrochemical Techniques|DNA|Ferrous Compounds|Gold|Electrode|Limit of Detection|DNA, Single-Stranded 40 BRAC1 30854067 Oncol Lett 2019 PMC6365902 10.3892/ol.2019.9884 1 0 0 0 Humans|Gene Ontology|*Triple-Negative Breast Cancer|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|BRCA1 protein, human|*BRCA1 Protein|Computational Biology|*Signal Transduction|Gene Expression Regulation, Neoplastic|Protein Interaction Mapping|Transcription Factors 40 BRSK1 30865617 Med. Sci. Monit. 2019 PMC6427931 10.12659/MSM.913057 1 25 0 135 Humans|*Glomerulonephritis, Membranous|Leukocytes, Mononuclear|MIRN328 microRNA, human|MicroRNAs|MIRN195 microRNA, human|MIRN192 microRNA, human|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Downregulation|mRNA|*Biomarkers|Computational Biology|Upregulation|Signal Transduction|Transcriptional Activation|BRSK1 protein, human 48 BRWD3 31714006 Am J Med Genet C Semin Med Genet 2019 10.1002/ajmg.c.31750 0 0 0 50 Male|Humans|*Intellectual Disability|*Macrocephaly|*Genes, X-Linked|*Syndrome|Phenotype|Hypotonia, Neonatal|*Obesity|Pedigree|Autism Spectrum Disorder|BRWD3 protein, human|Transcription Factors 25 BRWD3 31178897 Front Genet 2019 PMC6542989 10.3389/fgene.2019.00485 2 0 0 50 *Sequencing, Whole Exome|*DNA Copy Number Variations|*Neurodevelopmental Disorders|Exome|Sequence Analysis, DNA|Phenotype|Mutation 25 BRWD3 30628072 Clin. Genet. 2019 10.1111/cge.13504 0 0 0 50 Humans|*Syndrome|Mental Retardation, X-Linked 93|*Macrocephaly|*Mental Retardation, X-Linked|Intellectual Disability|Abnormalities, Multiple|Mutations|Pedigree|Transcription Factors|BRWD3 protein, human 25 Bsx 31808568 J. Pineal Res. 2019 PMC7122731 10.1111/jpi.12629 0 0 0 24 Humans|Female|Adult|Pregnancy|Rats|Animals|*Pineal Gland|*Genes, Homeobox|Melatonin|Homeodomain Proteins|Circadian Rhythm|Transcription Factors|Trans-Activators|Gene Expression Regulation, Developmental|Cyclic AMP|In Situ Hybridization 86 Bsx 31602413 Commun Biol 2019 PMC6779754 10.1038/s42003-019-0613-1 2 0 0 24 Animals|*Zebrafish|*Pineal Gland|*Genes, Homeobox|Zebrafish Proteins|Otx Transcription Factors|Trans-Activators|Gene Expression Regulation, Developmental|Retina|Circadian Rhythm 86 Bsx 31512802 Pediatr Transplant 2019 10.1111/petr.13573 0 0 0 24 Child|Humans|*Basiliximab|thymoglobulin|*Antilymphocyte Serum|*Liver Transplantation|Retrospective Studies|Immunosuppressive Agents|Tacrolimus|Graft Rejection|Kidney Transplantation|Antibodies, Monoclonal|Immunosuppression|Steroids|Biopsy 86 Bsx 31283665 Transplantation 2019 10.1097/TP.0000000000002804 0 0 0 24 Humans|Aged|*Kidney Transplantation|thymoglobulin|Globulins, Antithymocyte|Basiliximab|Graft Rejection|Immunosuppressive Agents|Graft Survival|Tacrolimus|Mycophenolic Acid|Antibodies, Monoclonal 86 Bsx 30761197 Int J Exerc Sci 2019 PMC6355126 0 0 0 24 *Lactate|Anaerobic Threshold|Physical Endurance|Exercise Test|Running|Exercise|Oxygen Consumption|Heart Rate|Analysis of Variance|Veins 86 Bsx 30608904 J. Mol. Endocrinol. 2019 10.1530/JME-18-0212 0 0 0 24 Animals|*Appetite Regulation|*Sincalide|*Glucagon-Like Peptide 1|*Acids, Fatty|cholecystokinin 8|*Cholecystokinin|Oncorhynchus mykiss|Hypothalamus|Eating|Neuropeptides|*Peptide Fragments|Hindbrain|MTOR protein, human|TOR Serine-Threonine Kinases|Fish Proteins|Oleic Acid|RNA, Messenger 86 BTBD9 31715135 Exp. Neurol. 2019 PMC6899185 10.1016/j.expneurol.2019.113111 1 1 0 90 Humans|Mice|Animals|*Restless Legs Syndrome|*Cerebral Cortex|Mice, Knockout|Nerve Tissue Proteins|Transcription Factors|Disease Models, Animal|Mutations|BTBD9 protein, human 67 BTBD9 31706190 Sleep Med. 2019 10.1016/j.sleep.2019.07.003 1 0 0 90 *Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Genetic Susceptibility|PTPRD protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Homeodomain Proteins|Genes, Homeobox|Genome-Wide Association Study|Transcription Factors|Polymorphism, Single Nucleotide|*Pain|Nerve Tissue Proteins|Case-Control Studies|High Mobility Group Proteins 67 BTBD9 31704978 Sci Rep 2019 PMC6841937 10.1038/s41598-019-52735-z 0 0 0 90 Humans|Mice|Animals|rotigotine|*Restless Legs Syndrome|*Renal Dialysis|*Sleep, REM|*Tetrahydronaphthalenes|*Thiophenes|Dopamine Agonist|*Sleep|End Stage Renal Disease|Dopamine|*Disease Models, Animal|*Injection 67 BTBD9 31665514 Sleep 2019 10.1093/sleep/zsz265 0 0 0 90 Humans|Female|*Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|Genome-Wide Association Study|Case-Control Studies|Polymorphism, Single Nucleotide|Transcription Factors|Nerve Tissue Proteins|Genetic Loci|Cohort Studies|Genotype 67 BTBD9 31444227 eNeuro 2019 PMC6787346 10.1523/ENEURO.0277-19.2019 3 2 0 90 *Restless Legs Syndrome|Genome-Wide Association Study|*Corpus Striatum|*Neostriatum|Nerve Tissue Proteins|Transcription Factors|*Gray Matter|Mutations 67 BTBD9 31004074 Neurology 2019 10.1212/WNL.0000000000007500 4 0 0 90 *Restless Legs Syndrome|Parkinson Disease|Essential Tremor|Tourettes Syndrome|Parkinsonian Syndromes 67 BTG4 31811028 J. Neurosci. 2019 PMC6975285 10.1523/JNEUROSCI.0786-19.2019 0 4 0 17 Schizophrenia|DRD2 protein, human|Dopamine D2 Receptor|Genetic Predisposition to Disease|Prefrontal Cortex|Brain|Networks, Gene 40 BTG4 31777931 Nucleic Acids Res. 2019 PMC6954448 10.1093/nar/gkz1111 0 1 0 17 Mice|Animals|*RNA, Messenger, Stored|*Zygotes|Embryo Development|*Genome|mRNA Decay|Mammalian Embryos|Gene Expression Regulation, Developmental|Oocytes|Preimplantation Embryos|Transcription Factor|mRNA|Btg4 protein, mouse|Cell Cycle Proteins 40 BTG4 31757970 Nat Commun 2019 PMC6876564 10.1038/s41467-019-13228-9 2 0 0 17 Animals|Mice|*RNA Isoforms|Poly A|*mRNA|Polyadenylation|Sequence Analysis, RNA|*Protein Isoforms|Oocytes 40 BTG4 31598710 Nucleic Acids Res. 2019 PMC6868374 10.1093/nar/gkz863 2 0 0 17 Female|Mice|Animals|*mRNA|*Transcriptome|*Oogenesis|mRNA, Maternal|Oocytes|mRNA Decay|Meiosis|Zygotes|Protein Biosynthesis|Cell Cycle Proteins|3' UTRs|Gene Expression Regulation, Developmental|Mice, Knockout|Maternal Effect|Btg4 protein, mouse 40 BTG4 31513655 PLoS ONE 2019 PMC6742393 10.1371/journal.pone.0222502 0 0 0 17 *Postural Balance|Reproducibility of Results 40 BTG4 30715134 Biol. Reprod. 2019 10.1093/biolre/ioz012 0 0 0 17 Pregnancy|Female|Mice|Animals|*Zygotes|mRNA, Maternal|Oocyte|Oogenesis|*Mammals|Embryonic Development|RNA Stability|Meiosis|Embryo, Mammalian|Gene Expression Regulation, Developmental|Cell Cycle Proteins|Activation, Transcriptional|*Birth|Genome|Btg4 protein, mouse 40 C1QTNF3 31556307 Artif Cells Nanomed Biotechnol 2019 10.1080/21691401.2019.1666864 1 8 0 239 Humans|*Apoptosis|TNF protein, human|*Tumor Necrosis Factor-alpha|NF-E2-Related Factor 2|Oxidative Stress|Retinal Pigment Epithelium|Heme Oxygenase-1|Cytoprotection|Reactive Oxygen Species|Epithelial Cells|Cell Survival|Glucose|Cell Line|Retinal Pigments 73 C1QTNF3 31428552 Anal Cell Pathol (Amst) 2019 PMC6681575 10.1155/2019/7405602 0 1 0 239 Humans|*Umbilical Veins|*Human Umbilical Vein Endothelial Cells|*Protective Agents|Apoptosis|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Cytoprotection|Signal Transduction|Reactive Oxygen Species|Cell Survival|Oxidative Stress|Glucose 73 C1QTNF3 31296837 Cell Death Dis 2019 PMC6624206 10.1038/s41419-019-1760-5 2 3 0 239 Mice|Animals|*Mesenchymal Stem Cells|*Complement C1q|Stroke Volume|Ventricular Function, Left|*Myocardial Infarction|Mesenchymal Stem Cell Transplantation|*Heart|Myocardium|Cell Proliferation|Apoptosis|Cell Survival|Disease Models, Animal|Tumor Necrosis Factors 73 C1QTNF3 31235116 Diabetes Metab Syndr 2019 10.1016/j.dsx.2019.04.047 0 0 0 239 Humans|*Complement C1q|Adipokines|Insulin Resistance|Adiponectin|Adipocytes|Blood Glucose|Tumor Necrosis Factors|Cytokines|Adipose Tissue|Lipid Metabolism|*Homeostasis 73 C1QTNF3 31204077 Gynecol. Oncol. 2019 10.1016/j.ygyno.2019.06.010 3 0 0 239 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cystadenocarcinoma, Serous|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 73 C1QTNF3 31182031 BMC Cardiovasc Disord 2019 PMC6558754 10.1186/s12872-019-1117-0 2 0 0 239 Humans|*Heart Failure|Stroke Volume|*Complement C1q|TNF protein, human|*Tumor Necrosis Factor-alpha|Biochemical Marker|Ventricular Function, Left|Ventricular Dysfunction, Left|Adipokines|*Morbidity 73 C1QTNF3 31129285 J. Neuroimmunol. 2019 10.1016/j.jneuroim.2019.576968 0 0 0 239 Humans|Female|*Apelin|*Multiple Sclerosis|Adiponectin|Tumor Necrosis Factor-alpha|C-Reactive Protein|Adipocytokines|Multiple Sclerosis, Relapsing-Remitting|Biomarkers|*Plasma 73 C1QTNF3 31074042 J. Cell. Physiol. 2019 10.1002/jcp.28801 0 1 0 239 Humans|Rats|Animals|*Complement C1q|*Fibrosis|*Kidney Diseases|*Signal Transduction|Ureteral Obstruction|Kidney|Transforming Growth Factor beta1|Smad3 Protein|Epithelial-Mesenchymal Transition|Adenovirus|Epithelial Cells|Collagen Type I|*Urinary Tract|Tumor Necrosis Factors 73 C1QTNF3 31009504 PLoS ONE 2019 PMC6476508 10.1371/journal.pone.0215617 1 3 0 239 Humans|*Insulin Resistance|*Diabetic Nephropathies|Diabetes Mellitus, Type 2|TNF protein, human|*Tumor Necrosis Factor-alpha|Adipokine|Biomarkers|Metabolic Syndrome|Inflammation|Interleukin-6|Coronary Artery Diseases|Case-Control Studies 73 C1QTNF3 30988781 Exp Ther Med 2019 PMC6447910 10.3892/etm.2019.7425 1 1 0 239 Rats|Animals|*Arthritis, Experimental|triptolide|*Phosphoinositide 3 Kinase|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Transcriptome|Vascular Endothelial Growth Factor A|*Phenanthrenes|*Diterpenes|*Signal Transduction|Synovial Membrane|*Epoxy Compounds|Rheumatoid Arthritis|Upregulation|Downregulation|Apoptosis|mRNA|Tumor Necrosis Factor-alpha 73 C1QTNF3 30732504 Ren Fail 2019 PMC6374918 10.1080/0886022X.2018.1561373 0 0 0 239 Humans|Rats|Animals|Renal Dialysis|*Chronic Kidney Disease|Adipokine|Adiponectin|Body Mass Index|Obesity|Adipocyte|Biomarkers|Cardiovascular Diseases|Tumor Necrosis Factors 73 C1QTNF3 30641739 Diabetes Metab Syndr 2019 10.1016/j.dsx.2018.10.004 1 0 0 239 Humans|Young Adult|*Adipokine|*Complement C1q|Egypt|Insulin Resistance|TNF protein, human|Tumor Necrosis Factor-alpha|Obesity|Diabetes Mellitus, Type 2|Glucose|*Protective Agents 73 C1QTNF6 31513814 Life Sci. 2019 10.1016/j.lfs.2019.116862 1 10 0 110 Animals|Rats|*Angiotensin II|Endothelial Cells|*Rats, Wistar|*Hypertension|Spontaneously Hypertensive Rats|Blood Pressure|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Upregulation|miRNA|Endothelium, Vascular|Reactive Oxygen Species|Phosphorylation|Signal Transduction|Cell Proliferation|Downregulation|Aorta|CTRP6 protein, rat 33 C1QTNF6 31292940 In Vitro Cell. 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Immunopharmacol. 2019 10.1016/j.intimp.2019.105934 1 3 0 1 *Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|*AMP-Activated Protein Kinases|*Complement C1q|*Atherosclerosis|Foam Cell|Lipoproteins, LDL|TYRP1 protein, human|*Membrane Glycoproteins|Macrophages|Signal Transduction|Inflammation|Smooth Muscle Cell|Endothelium 38 C1QTNF9B 31182031 BMC Cardiovasc Disord 2019 PMC6558754 10.1186/s12872-019-1117-0 2 0 0 1 Humans|*Heart Failure|Stroke Volume|*Complement C1q|TNF protein, human|*Tumor Necrosis Factor-alpha|Biochemical Marker|Ventricular Function, Left|Ventricular Dysfunction, Left|Adipokines|*Morbidity 38 C1QTNF9B 31159525 Zhonghua Nei Ke Za Zhi 2019 10.3760/cma.j.issn.0578-1426.2019.06.010 0 0 0 1 Humans|*Complement C1q|*Factor 9|Adiponectin|Glycoproteins|Atherosclerosis|Tumor Necrosis Factor Receptor-Associated Peptides and Proteins|*Cerebral Infarction|Tumor Necrosis Factors 38 C1QTNF9B 31129285 J. 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U.S.A. 2019 PMC6778232 10.1073/pnas.1904311116 1 0 0 16 Genome-Wide Association Study|Diabetes Mellitus, Type 2|Insulin-Secreting Cells|Insulin Secretion|Insulin|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Transcription Factors|Genotype 24 C2CD4B 30804981 Front Genet 2019 PMC6371051 10.3389/fgene.2019.00036 2 4 0 16 Animals|Female|*Buffaloes|*Milk|*Genome-Wide Association Study|*Transcriptome|Lactation|*Phenotype|Mammary Glands, Animal|*Bison 24 CALB2 31713514 Elife 2019 PMC6908433 10.7554/eLife.49190 0 0 0 555 CALB2 protein, human|*Calbindin 2|*Spinal Cord Dorsal Horn|*Neurons|Interneurons|Neuralgia|Analgesics|Calcium-Binding Proteins 1236 CALB2 31671889 Int J Mol Sci 2019 PMC6873109 10.3390/ijms20215391 2 0 0 555 Humans|*Cisplatin|CALB2 protein, human|*Calbindin 2|*Wnt Signaling Pathway|*Drug Resistance, Neoplasm|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|Antineoplastic Agents|beta Catenin|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Proliferation 1236 CALB2 31509615 Int. J. Cancer 2019 10.1002/ijc.32676 0 0 0 555 Female|Humans|*Ovarian Cancer|*Platinum|CALB2 protein, human|*Calbindin 2|Neoplasm Recurrence, Local|*Carcinoma, Ovarian Epithelial|*Prognosis|Cystadenocarcinoma, Serous|Neoplasms, Glandular and Epithelial|Cytoreduction Surgical Procedures|Drug Resistance, Neoplasm|CA-125 Antigen|Biomarkers, Tumor|Neoplasm Staging|Survival Rate 1236 CALB2 31427537 Proc. Natl. Acad. Sci. 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Biochem. Biophys. 2019 10.1016/j.abb.2019.05.004 0 3 0 112 Calcium-Calmodulin-Dependent Protein Kinase Type 1|Calcium-Calmodulin-Dependent Protein Kinase Kinase|Phosphorylation|Amino Acid Sequence|Amino Acid Substitution|Cloning, Molecular 60 CAMK1D 30710230 J. Assist. Reprod. Genet. 2019 PMC6541693 10.1007/s10815-019-01410-3 1 0 0 112 Female|Humans|*Cumulus Cells|*Oogenesis|Blastocyst|Oocytes|Embryo Development|Embryo Implantation|Ovarian Follicle 60 CAMK1D 30669351 Genes (Basel) 2019 PMC6356198 10.3390/genes10010061 3 1 0 112 Animals|*Newcastle disease virus|Genome-Wide Association Study|*Chickens|Newcastle Disease|*Genomics|*Stress, Heat|Quantitative Trait Loci|*Heat Stress Disorders|Single Nucleotide Polymorphism|Gene Expression Profiling|Hot Temperature 60 CAMK1D 30627993 J. Assist. Reprod. Genet. 2019 PMC6439096 10.1007/s10815-018-01398-2 2 0 0 112 Pregnancy|Female|Humans|*Single Embryo Transfer|*Live Birth|Prospective Studies|*Time-to-Pregnancy|*Multiple Pregnancy|Embryo Transfer|Pregnancy Rate|Fertilization in Vitro|Sperm Injections, Intracytoplasmic|Rates, Birth|Pregnancy Outcome|Maternal Age|*Embryo, Mammalian 60 CAMK2N1 31876385 J. Cell. Mol. Med. 2019 PMC7011149 10.1111/jcmm.14050 1 0 0 115 Humans|Male|*Docetaxel|*Prostate Cancer|*Downregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|Apoptosis|Prostate|Cell Proliferation|Taxoids|Cell Line, Tumor|Drug Resistance, Neoplasm|Up-Regulation|*Proteins|Xenograft Model Antitumor Assays|PC3 Cells|CAMK2N1 protein, human|Mirn129 microRNA, human 60 CAMK2N1 31762801 J Cancer 2019 PMC6856586 10.7150/jca.34564 0 5 0 115 60 CAMK2N1 31598163 J Cancer 2019 PMC6775516 10.7150/jca.32582 0 1 0 115 *Oral Cancer|Carcinoma, Squamous Cell|Cellular Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Cycle|Up-Regulation|Immunohistochemistry|G1 Phase|Downregulation|Lymphatic Metastasis 60 CAMK2N1 31452083 Hum. Cell 2019 10.1007/s13577-019-00276-y 0 0 0 115 Mice|Animals|*Multiple Myeloma|Mice, Nude|*Oncogenesis|RNA, Micro|Cell Proliferation|*Oncogenes|Cell Movement|Gene Expression Regulation, Neoplastic|RNA Interference|Cell Line, Tumor|Upregulation|*Proteins|Cell Cycle|mRNA 60 CAMK2N1 31352197 Transl Oncol 2019 PMC6664230 10.1016/j.tranon.2019.07.002 0 4 0 115 Mice|Animals|*Carcinoma, Hepatocellular|*T Cell Factor 4|3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione|*Down-Regulation|*Liver Neoplasms|*Oncogenes|*Piperidones|*Quinazolinones|*Protein Isoforms|*Oncogenesis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|beta Catenin|Signal Transduction 60 CAMK2N1 31327268 Hypertension 2019 PMC6686962 10.1161/HYPERTENSIONAHA.118.12409 0 3 0 115 Rats|Animals|*Blood Pressure|*Insulin Resistance|*Adiposity|Diabetes Mellitus, Type 2|*Blood Pressure Determination|Spontaneously Hypertensive Rat|Hypertrophy, Left Ventricular|Hypertension|*Obesity|Left Ventricle 60 CAMK2N1 31242498 Gerontology 2019 10.1159/000500742 0 1 0 115 Rats|Animals|*Beclin-1|*AMP-Activated Protein Kinases|*Proteomics|*Protein Carbonylation|*Protein Kinases, Calmodulin-Dependent|*Hippocampus|*Autophagy|Oxidative Stress|Physical Conditioning, Animal|TOR Serine-Threonine Kinases|Signal Transduction|Oxidation-Reduction 60 CAMK2N1 30923740 eNeuro 2019 PMC6437658 10.1523/ENEURO.0473-18.2019 2 39 0 115 Male|Rats|Animals|*Preoptic Area|*Angiotensin II|*Rats, Sprague-Dawley|AVP protein, human|*Vasopressin|*Neurophysins|Subfornical Organ|*Drinking Behavior|Paraventricular Hypothalamic Nucleus|Neurons|Water-Electrolyte Balance 60 CAMK2N1 30735733 Life Sci. 2019 10.1016/j.lfs.2019.02.012 0 4 0 115 Mice|Animals|*Alzheimer Disease|FYN protein, human|*Proto-Oncogene Proteins c-fyn|panaxadiol|Neurodegenerative Diseases|*Ginsenosides|Amyloid beta-Peptides|Amyloid beta-Protein Precursor|tau Proteins|Mice, Transgenic|Memory Loss|Synapses|Hippocampus|Disease Models, Animal|Phosphorylation|Fyn protein, mouse 60 CAMK2N1 30662904 Biomed Res Int 2019 PMC6312609 10.1155/2018/2828143 1 1 0 115 Male|Rats|Animals|*Proteomics|*Rats, Sprague-Dawley|*Signal Transduction|*Apoptosis|*Protein Carbonylation|TOR Serine-Threonine Kinases|Proto-Oncogene Proteins c-akt|Physical Conditioning, Animal|Phosphorylation|Corpus Striatum 60 CAMK2N1 30651076 BMC Cancer 2019 PMC6335725 10.1186/s12885-018-5221-9 1 0 0 115 Humans|Carcinoma, Ductal, Breast|Prognosis|Carcinoma, Papillary|Survival Rate|Retrospective Studies|CD1D protein, human|*Antigens, CD1d|Case-Control Studies|*Breast Neoplasms|Tumor Microenvironment|PJA2 protein, human|Ubiquitin-Protein Ligases 60 CAMTA1 31814291 Pediatr Blood Cancer 2019 10.1002/pbc.28095 0 0 0 104 Child|Infant|Adolescent|Humans|Kasabach-Merritt Syndrome|Hemangioendothelioma|Sarcoma, Kaposi|*Treatment Outcome|*Registry|Vascular Neoplasms|Combined Modality Therapy|Endothelial Cells 124 CAMTA1 31803243 Front Genet 2019 PMC6872681 10.3389/fgene.2019.01174 0 0 0 104 Dogs|Animals|Humans|*Polymorphism, Single Nucleotide|*Genome|Breeding|Linkage Disequilibrium|Genetics, Population|Selection, Genetic|Genetic Variation|Genotype|Homozygote|*Chinese|Genomics|China|Mongolia|Kazakhstan 124 CAMTA1 31768366 Ocul Oncol Pathol 2019 PMC6873054 10.1159/000496207 0 0 0 104 *Hemangioma|Hemangioendothelioma, Epithelioid|Angiolymphoid Hyperplasia with Eosinophilia|Diagnosis, Differential|Biomarkers, Tumor|*B Cells|Proto-Oncogene Proteins c-fos 124 CAMTA1 31757015 Int J Mol Sci 2019 PMC6928622 10.3390/ijms20235828 0 4 0 104 Pregnancy|Humans|Female|*Diabetes, Gestational|*DNA Methylation|*B-DNA|Epigenesis, Genetic|Fetal Blood|*African Continental Ancestry Group 124 CAMTA1 31733371 Mol Plant 2019 10.1016/j.molp.2019.10.016 1 2 0 104 *Salicylic Acid|*Transcription Factors|N-hydroxypipecolic acid|Plant Immunity|*Pipecolic Acids|Arabidopsis Proteins|Arabidopsis|Gene Expression Regulation, Plant|Pseudomonas syringae|Calmodulin-Binding Proteins|Calmodulin|Plant Diseases|Intramolecular Transferases|Promoter Regions, Genetic|Signal Transduction|Chromatin Immunoprecipitation|Mutation|CBP60g protein, Arabidopsis 124 CAMTA1 31733370 Mol Plant 2019 10.1016/j.molp.2019.11.001 0 6 0 104 *Arabidopsis|pipecolic acid|*Pipecolic Acids|Arabidopsis Proteins|Salicylic Acid|Plant Immunity|Pseudomonas syringae|Gene Expression Regulation, Plant|Transcription Factors|Plant Diseases|Genes, Plant|Signal Transduction|Transaminases|Calmodulin 124 CAMTA1 31662570 In Vivo 2019 PMC6899089 10.21873/invivo.11736 1 0 0 104 *Hemangioendothelioma, Epithelioid|*Hemangiosarcoma|*Diagnosis, Differential|Immunohistochemistry|Transcription Factors|Trans-Activators|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Neoplasms, Vascular Tissue|Calcium-Binding Proteins|In Situ Hybridization, Fluorescence|Oncogene Proteins, Fusion|Intracellular Signaling Peptides and Proteins|*Liver Neoplasms|Biomarkers, Tumor|Cell Nucleus 124 CAMTA1 31589365 Mol. Reprod. Dev. 2019 10.1002/mrd.23278 1 0 0 104 Humans|Male|Rats|Animals|*Sperm|Spermatids|Spermatocytes|Spermatogenesis|*Meiosis|*Gene Expression|Infertility, Male|Transcriptome Analysis|Meiotic Prophase I|Massively Parallel Sequencing|DPF3 protein, human|DNA-Binding Proteins|Transcription Factors|LY6K protein, human|Antigens, Ly|GPI-Linked Proteins|CPEB2 protein, human|RNA-Binding Proteins 124 CAMTA1 31577358 JAMA Netw Open 2019 PMC6777396 10.1001/jamanetworkopen.2019.12416 0 0 0 104 Humans|Adult|Child|*Hemangioendothelioma, Epithelioid|WWTR1 protein, human|Intracellular Signaling Peptides and Proteins|Transcription Factors|*Neoplasms, Vascular Tissue|Trans-Activators|Calcium-Binding Proteins|*Genomics|In Situ Hybridization, Fluorescence|Biomarkers, Tumor|*Sarcoma|Sequencing, Next-Generation 124 CAMTA1 31537895 Mod. Pathol. 2019 PMC7228463 10.1038/s41379-019-0368-8 1 0 0 104 Humans|Adult|Child|*Hemangioendothelioma, Epithelioid|*Prognosis|*Neoplasms, Vascular Tissue|Translocation, Genetic|WWTR1 protein, human|Intracellular Signaling Peptides and Proteins|Transcription Factors|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Oncogene Proteins, Fusion|Gene Fusion|Trans-Activators|In Situ Hybridization, Fluorescence|Calcium-Binding Proteins|Angiosarcomas|*Sarcoma|Biomarkers, Tumor|Base Sequence 124 card14 31849081 J. Cutan. Pathol. 2019 10.1111/cup.13633 1 0 0 92 Pityriasis Rubra Pilaris|CARD14 protein, human|CARD Signaling Adaptor Proteins|Guanylate Cyclase|Psoriasis|*Exanthema|Membrane Proteins|Mutations 97 card14 31813117 Am J Clin Dermatol 2019 10.1007/s40257-019-00492-0 1 0 0 92 Humans|Quality of Life|Neoplasm Recurrence, Local|*Psoriasis|Skin|CARD Signaling Adaptor Proteins|Interleukins|*Skin Diseases, Vesiculobullous|Guanylate Cyclase|*Exanthema|Mutations|Membrane Proteins|CARD14 protein, human|IL36RN protein, human 97 card14 31544986 Mol. Reprod. Dev. 2019 10.1002/mrd.23273 0 0 0 92 Animals|*Anguilla|Japan|Molecular Sequence Annotation|Genome|Transcriptome|Messenger RNA|Databases, Genetic|Gene Expression Regulation, Developmental 97 card14 31486084 J. Cell. Physiol. 2019 10.1002/jcp.29161 1 5 0 92 Humans|*Keratinocytes|CARD Signaling Adaptor Proteins|Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein|*Poly I-C|Signal Transduction|Guanylate Cyclase|IRF3 protein, human|Interferon Regulatory Factor-3|TLR3 protein, human|Toll-Like Receptor 3|Adaptor Proteins, Signal Transducing|NF-kappa B|Psoriasis|Protein-Serine-Threonine Kinases|Membrane Proteins|*Inflammation|HEK293 Cells|Motor Vehicles 97 card14 31353537 J. Dermatol. 2019 10.1111/1346-8138.15034 0 0 0 92 Humans|*Heterozygote|*Psoriasis|TNFAIP3 protein, human|*Tumor Necrosis Factor alpha-Induced Protein 3|Genetic Predisposition to Disease|Interleukins|Asian Continental Ancestry Group|Mutation|*Exanthema|Phenotype|*Skin Diseases, Vesiculobullous|CARD14 protein, human|Guanylate Cyclase|Membrane Proteins|CARD Signaling Adaptor Proteins|IL36RN protein, human 97 card14 31323190 Exp. Mol. Pathol. 2019 PMC7318844 10.1016/j.yexmp.2019.104286 1 1 0 92 Humans|Mice|Animals|*Gain of Function Mutation|Genome-Wide Association Study|CARD Signaling Adaptor Proteins|Psoriasis|Guanylate Cyclase|Skin|*Modifier Gene|Arthritis, Psoriatic|Keratinocytes|Mutations|NF-kappa B|Membrane Proteins|Signal Transduction|Inflammation|CARD14 protein, human 97 card14 31286971 Pediatr Rheumatol Online J 2019 PMC6615224 10.1186/s12969-019-0336-3 1 2 0 92 *Ustekinumab|*Whole Exome Sequencing|*Psoriasis|CARD Signaling Adaptor Proteins|Pityriasis Rubra Pilaris|Guanylate Cyclase|Membrane Proteins|Pedigree|Mutation 97 card14 31156649 Front Immunol 2019 PMC6532024 10.3389/fimmu.2019.01107 1 0 0 92 Tifab protein, human|*TNF Receptor-Associated Factor 6|*Cells, Epithelial|Signal Transduction|NF-kappa B|Psoriasis|RELA protein, human|Transcription Factor RelA|Interleukin-17|Skin|Inflammation|Cytokines|Ubiquitin Ligase E3|Tissues, Epithelial 97 card14 31106887 J. Dermatol. 2019 10.1111/1346-8138.14925 2 1 0 92 Humans|Female|Child, Preschool|*Acitretin|*Dermatitis, Exfoliative|*Gabapentin|*Psoriasis|Keratoderma, Palmoplantar|Dermatitis|*Exanthema|Desmoglein 1|*Cachexia|Wasting Syndrome|Mutation|*Skin Diseases, Vesiculobullous|Hypersensitivity|Pedigree|*Misdiagnosis|CARD14 protein, human|Guanylate Cyclase|Membrane Proteins 97 CARD6 31841440 Aging (Albany NY) 2019 PMC6949089 10.18632/aging.102561 0 0 0 74 Mice|Animals|*Reactive Oxygen Species|Quality of Life|*Inflammation|*Injury, Spinal Cord|*Oxidative Stress|Signal Transduction|NF-kappa B|Apoptosis|Microglia|Mice, Knockout|*Cell Death|Lipopolysaccharides|Cytokines|Mice, Transgenic 30 CARTPT 31692367 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2019 10.1152/ajpregu.00264.2019 0 0 0 1118 Animals|*Oncorhynchus mykiss|*Hypothalamus|*Energy Metabolism|Neuropeptide Y|Eating|Neuropeptides|*Liver|AMP-Activated Protein Kinases|*Vagus Nerve|mRNA|Glucose|*Nervous System Physiological Phenomena 39 CARTPT 31166300 Pain 2019 10.1097/j.pain.0000000000001636 1 0 0 1118 Mice|Animals|*Dynorphins|*Interneurons|Posterior Horn Cells|Horn, Dorsal|Pain|Galanin|Pain Threshold|Neurons|cocaine- and amphetamine-regulated transcript protein|Nerve Tissue Proteins|NOS1 protein, human|Nitric Oxide Synthase Type I|Pruritus|prepronociceptin|Protein Precursors|Receptors, Opioid|Gucy2d protein, mouse|Guanylate Cyclase 39 CARTPT 31150057 Endocrinology 2019 10.1210/en.2019-00319 4 15 0 1118 Pregnancy|Humans|Animals|Mice|Adult|Female|*Diabetes, Gestational|cocaine- and amphetamine-regulated transcript protein|*Ovary|*Promoter Regions, Genetic|*Nerve Tissue Proteins|Epigenesis, Genetic|DNA Methylation|EZH2 protein, human|Enhancer of Zeste Homolog 2 Protein|*Prenatal Care|Leptin|Signal Transduction|*Subfertility|Obesity|Histones|5-hydroxymethylcytosine|5 Methylcytosine|*Epigenetic 39 CARTPT 30733682 Front Physiol 2019 PMC6353792 10.3389/fphys.2018.01901 3 0 0 1118 Animals|*Fasting|Hypothalamus|Agouti-Related Protein|Neuropeptide Y|Neuropeptides|Receptors, Ghrelin|Intake Regulation, Food|Ghrelin|Pro-Opiomelanocortin|Eating|*Upregulation|*Transcriptional Activation|mRNA 39 CARTPT 30694175 Elife 2019 PMC6384028 10.7554/eLife.40970 3 2 0 1118 Mice|Animals|*Leptin|leptin receptor, human|Receptor, Leptin|Arcuate Nucleus|Pro-Opiomelanocortin|Agouti-Related Protein|Obesity|*Signal Transduction|Hypothalamus|Energy Expenditure|Neurons 39 CASC2 31728180 Cell Biosci 2019 PMC6842511 10.1186/s13578-019-0353-4 0 5 0 147 *RNA, Long Noncoding|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Gene Expression Regulation, Neoplastic|*Disease Progression|MicroRNAs|Cell Proliferation|Cell Movement|Down-Regulation|Carcinoma, Squamous Cell|Cell Line, Tumor|Tumor Suppressor Proteins|Cell Survival|*Suppressor of Cytokine Signaling Proteins 96 CASP5 31886185 Biomed Res Int 2019 PMC6925759 10.1155/2019/2506843 0 0 0 94 *Carcinoma, Renal Cell|Kidney Neoplasms|Prognosis|Gene Expression Profiling|Gene Regulatory Networks|Computational Biology|Protein Interaction Maps|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Tumor Microenvironment|Transcriptome|Kaplan-Meier Estimate|Databases, Factual 152 CASP5 31611962 Oncol Lett 2019 PMC6781674 10.3892/ol.2019.10816 0 0 0 94 Humans|*Prognosis|*Stomach Neoplasms|CASP2 protein, human|Caspase 2|CASP9 protein, human|Caspase 9|Gene Expression Regulation, Neoplastic|CASP10 protein, human|Caspase 10|Kaplan-Meier Estimate|Disease-Free Survival|Biomarkers, Tumor|CASP3 protein, human|CASP3|RNA, Messenger|Caspases|Cysteine Endopeptidases 152 CASP5 31201888 J. Allergy Clin. Immunol. 2019 10.1016/j.jaci.2019.06.003 0 0 0 94 *Gain of Function Mutation|CEBPE protein, human|CCAAT-Enhancer-Binding Proteins|NLR Family, Pyrin Domain-Containing 3 Protein|Leukocyte Disorders|Inflammasomes|Neutrophils|*Mutation|Transcription Factor|Gene Expression Regulation 152 CASP5 31045366 J Chem Inf Model 2019 10.1021/acs.jcim.9b00057 0 0 0 94 *Proteins|Protein Conformation|*Knowledge Bases|Databases, Protein 152 CASP5 30961396 Immunol. Invest. 2019 10.1080/08820139.2019.1586917 0 0 0 94 *Diabetes Mellitus, Type 2|*Transcriptome|*Leukocytes|Inflammation|Obesity|NF-kappa B|Body Mass Index|Cytokines|Leukocytes, Mononuclear|*Microarray Analysis 152 CASP5 30867653 Cancer Cell Int. 2019 PMC6399908 10.1186/s12935-019-0753-x 2 6 0 94 Humans|Male|*Transcriptome|*DNA Methylation|Bioinformatics|*Prostate Cancer|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Databases, Genetic|Protein Interaction Maps|Biomarkers, Tumor 152 CASP5 30760013 Arterioscler. Thromb. Vasc. Biol. 2019 PMC6436998 10.1161/ATVBAHA.118.312246 6 0 0 94 Humans|Male|Adult|Female|*Inflammasomes|Endothelial Cells|Proteomics|*Signal Transduction|NLR Family, Pyrin Domain-Containing 3 Protein|NF-kappa B|Caspase 1|Interleukin-1beta|*Psoriasis|Cytokines|Carrier Proteins|Reactive Oxygen Species 152 CASP5 30604868 J. Cell. Physiol. 2019 10.1002/jcp.28035 0 1 0 94 Humans|CASP3 protein, human|*Caspase 3|*Periodontal Ligament|*Caspases|*Programmed Cell Death|Cells, Cultured|Stress, Mechanical|Signal Transduction|Upregulation 152 CASZ1 31858748 Mol Genet Genomic Med 2019 PMC7005626 10.1002/mgg3.1098 1 0 0 1001 *Psoriasis|Arthritis, Psoriatic|Genetic Predisposition to Disease|Polymorphism, Genetic|Case-Control Studies|Skin 61 CASZ1 31642367 J Am Heart Assoc 2019 PMC6898816 10.1161/JAHA.119.013228 1 2 0 1001 Humans|*Epigenome|Bayes Theorem|CpG Islands|DNA Methylation|Epigenesis, Genetic|*Cohort Studies|Genome-Wide Association Study|Transcriptome|Model, Linear|Zinc Fingers 61 CASZ1 31570750 Sci Rep 2019 PMC6769056 10.1038/s41598-019-50586-2 0 0 0 1001 Varicose Veins|*Veins|Venous Insufficiency|*Chronic Disease|Odds Ratio|Genotype|Zinc Fingers|Netherlands|New Zealand 61 CASZ1 31545351 Am. J. Hypertens. 2019 PMC6856621 10.1093/ajh/hpz150 0 0 0 1001 Humans|*Genome-Wide Association Study|*Pharmacogenetics|*Hypertension|Antihypertensive Agents|Blood Pressure|African Americans|Risk Factors 61 CASZ1 31481981 Dis. Markers 2019 PMC6701416 10.1155/2019/1342161 0 0 0 1001 *Carcinoma, Renal Cell|*Prognosis|Kidney Neoplasms|Biomarkers, Tumor|Transcription Factor|Gene Expression Regulation, Neoplastic|Kidney|*Proteomics 61 CASZ1 31268246 Mol Genet Genomic Med 2019 PMC6687865 10.1002/mgg3.828 2 1 0 1001 Familial dilated cardiomyopathy|*Cardiomyopathy, Dilated|*Heterozygote|*Frameshift Mutation|Isolated Noncompaction of the Ventricular Myocardium|Mutation|DNA-Binding Proteins|Transcription Factors|*Cardiomyopathy|Mutation, Missense 61 CASZ1 31099773 Mol. Biol. (Mosk.) 2019 10.1134/S0026898419020150 0 0 0 1001 Animals|*Gene Regulatory Networks|Transcription Factors|Drosophila Proteins|Drosophila|Drosophila melanogaster|POU Domain Factors|Homeodomain Proteins|*Neural Stem Cells|Body Patterning|Gene Expression Regulation, Developmental|Kruppel-Like Transcription Factors|Embryo, Nonmammalian|Animals, Genetically Modified|Regulatory Gene|Neurons|Central Nervous System|*Biological Evolution|hunchback protein, Drosophila 61 CASZ1 30998689 PLoS Genet. 2019 PMC6490943 10.1371/journal.pgen.1008110 0 0 0 1001 Humans|*Varicose Veins|Genome-Wide Association Study|Genetic Predisposition to Disease|*Extremities, Lower|Mendelian Randomization Analysis|Transcription Factors|Phenotypes|Followup Studies 61 CASZ1 30833758 Nat Ecol Evol 2019 10.1038/s41559-019-0814-5 2 0 0 1001 Animals|Humans|*Pigmentation|*Genome|Sympatric Species|*Chromosomes B|Genetic Speciation|Gene Flow|Selection, Genetic|*Genomics|Microsatellite Repeats|Genetic Variation|*Vision|Genetic Linkage|Phenotype|Fishes|Linkage Disequilibrium|Opsins|Chromosomes|Caribbean 61 CCBE1 31633297 Am. 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A 2019 10.1002/ajmg.a.61392 0 0 0 132 Humans|Hennekam lymphangiectasia lymphedema syndrome|Lymphangiectasis, Intestinal|Craniofacial Abnormalities|Lymphedema|Homozygote|Genotype|Phenotype|Alleles|Mutation|Pedigree|*Syndrome|Calcium-Binding Proteins|ADAMTS3 protein, human|ADAMTS Proteins|Procollagen N-Endopeptidase|CCBE1 protein, human|Tumor Suppressor Proteins 69 CCBE1 31291246 PLoS ONE 2019 PMC6619597 10.1371/journal.pone.0213702 1 0 0 132 Animals|Mice|*Sequencing, RNA|*Transcriptome Profiling|Molecular Sequence Annotation|*Lung|Transcription Factor|*Base Sequence|*Whole Exome Sequencing|Transcriptome|Gene Expression Regulation, Developmental|Nuclear Proteins|Transcription, Genetic|Mice, Knockout|Organogenesis|Signal Transduction|IGF1 protein, human|IGF-1|Brain|RNA 69 CCBE1 31099754 Elife 2019 PMC6588350 10.7554/eLife.44478 2 12 0 132 Humans|Male|VEGFD protein, human|*Vascular Endothelial Growth Factor D|*Vascular Endothelial Growth Factor C|kallikrein-related peptidase 3, human|*Prostate-Specific Antigen|*Cathepsin D|Endothelial Cells|FLT4 protein, human|VEGFR-3|Kallikrein|Lymphangiogenesis|Lymphatic Vessels|Seminal Plasma|ADAMTS3 protein, human|ADAMTS Proteins|Procollagen N-Endopeptidase|CCBE1 protein, human|Calcium-Binding Proteins 69 CCBE1 30853196 J. Pediatr. 2019 10.1016/j.jpeds.2018.12.003 0 0 0 132 Child|Humans|*Protein-Losing Enteropathies|*Phenotype|*Genotype|Homozygote|*Chinese|Pedigree|*Cohort Studies|Sequencing, Next-Generation|Mutation|Diacylglycerol O-Acyltransferase 69 CCDC170 31246104 Climacteric 2019 10.1080/13697137.2019.1627313 1 0 0 50 22 CCDC170 30982901 Nucleic Acids Res. 2019 PMC6547407 10.1093/nar/gkz262 2 2 0 50 22 CCDC170 30601066 Climacteric 2019 10.1080/13697137.2018.1538339 2 0 0 50 22 CCDC88A 31871268 Mol. Cancer Ther. 2019 10.1158/1535-7163.MCT-18-1233 1 0 0 649 Humans|*Cyclic Nucleotide Phosphodiesterases, Type 3|Neoplastic Stem Cells|Signal Transduction|Cell Line, Tumor|Cilostazol|Cell Proliferation|CCDC88A protein, human|Microfilament Proteins|Vesicular Transport Proteins 131 CCDC88A 31363053 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6697900 10.1073/pnas.1906658116 6 3 0 649 Humans|*Signal Transduction|GTP-Binding Protein alpha Subunits, Gi-Go|G-Protein-Coupled Receptors|Heterotrimeric G-Proteins|Protein Binding|Vesicular Transport Proteins|Guanine Nucleotide Exchange Factors|Microfilament Proteins|Amino Acid Sequence|Models, Molecular|HeLa Cells 131 CCDC88A 31080558 Oncotarget 2019 PMC6499602 10.18632/oncotarget.26880 4 4 0 649 Mice|Animals|*RNA, Small Interfering|*mRNA|*Pancreatic Cancer|Chitosan|Nanoparticles|*Neoplastic Processes|Gene Knockdown Techniques|Polyethylene Glycols|Mice, Nude|*Pancreas|Cell Line, Tumor|Genetic Therapy|*RNA, Double-Stranded|Xenograft Model Antitumor Assays 131 CCDC88A 31017840 Mol. Biol. Cell 2019 PMC6727633 10.1091/mbc.E18-10-0630 2 7 0 649 *Cyclic AMP|Signal Transduction|G Protein|Vesicular Transport Proteins|Microfilament Proteins|G-Protein-Coupled Receptors|Phosphorylation|Cell Movement|Receptor Protein-Tyrosine Kinases|*Model, Computer|ErbB Receptors 131 CCDC88A 30935690 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.03.167 0 8 0 649 Humans|*Protein Phosphatase 2A|Microfilament Proteins|Lymphatic Metastasis|Vesicular Transport Proteins|Cell Movement|Cell Line, Tumor|Cell Proliferation|Phosphorylation 131 CCL14 31691483 Int Wound J 2019 10.1111/iwj.13257 0 0 0 47 Rabbits|Animals|*Cicatrix, Hypertrophic|*Th2 Cells|*Chemokines|Ear|CCL19 protein, human|Chemokine CCL19|Wound Healing|CCL21 protein, human|Chemokine CCL21|Disease Models, Animal|RNA, Messenger|Real Time Polymerase Chain Reaction 77 CCL14 31641099 Cell Death Dis 2019 PMC6805940 10.1038/s41419-019-1966-6 2 2 0 47 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Mice, Nude|*Prognosis|*Genes, Tumor Suppressor|Wnt Pathway|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Cell Cycle Checkpoints|Downregulation|beta Catenin|Cell Movement|MicroRNAs|Cell Line, Tumor|Apoptosis|Catenins|*Chemokines, CC|CCL14 protein, human 77 CCL14 31355141 Front Oncol 2019 PMC6636394 10.3389/fonc.2019.00624 0 0 0 47 77 CCL14 30850364 Cancer Genomics Proteomics 2019 PMC6489687 10.21873/cgp.20118 3 0 0 47 Male|*Proteomics|Electrophoresis, Gel, Two-Dimensional|Proteome|Neoplasm Proteins|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Biomarkers, Tumor|Blood Proteins 77 CCL15 31835202 Mol. Immunol. 2019 10.1016/j.molimm.2019.11.014 0 0 0 148 *Myeloid-Derived Suppressor Cells|*Tumor|*Chemokines|Tumor Microenvironment|Tumor Escape|Immunotherapy|Signal Transduction|Receptors, Interleukin-8A|Cell Differentiation|Receptors, Interleukin-8B 118 CCL15 31814701 Mol. Vis. 2019 PMC6857774 0 0 0 148 *Retinal Vein Occlusion|*Chemokines|Macular Edema|Vitreous Body|Vitrectomy|Vascular Endothelial Growth Factor A|*Ischemia 118 CCL15 31629996 J Psychiatr Res 2019 10.1016/j.jpsychires.2019.10.008 0 0 0 148 Humans|Depressive Disorder, Major|*Suicide|Bipolar Disorder|Schizophrenia|*Autopsy|*Brain|Dorsolateral Prefrontal Cortex|CCL15 protein, human|Chemokines, CC|CCL13 protein, human|Monocyte Chemoattractant Proteins|CCL20 protein, human|Chemokine CCL20|Macrophage Inflammatory Proteins 118 CCL15 31416084 Respiration 2019 10.1159/000500576 1 0 0 148 Humans|*Chemokines|*Hypersensitivity Pneumonitis|*Prognosis|*Biomarkers|Bronchoalveolar Lavage Fluid|Lung|*Ligands 118 CCL15 31096719 Int J Mol Sci 2019 PMC6566870 10.3390/ijms20102417 2 3 0 148 *Receptor, CCR1|CCL15 protein, human|Macrophage Inflammatory Proteins|*Chemokines|Chemokines, CC|Ligands|Signal Transduction|Cell Line, Tumor|Chemokine CCL7 118 CCL15 31001733 Cell Oncol (Dordr) 2019 10.1007/s13402-019-00446-y 1 5 0 148 *Gefitinib|*Squamous Cell Carcinoma of Head and Neck|*Metformin|*Macrophages|Macrophage Inflammatory Proteins|Cell Line, Tumor|Chemokines, CC|Signal Transduction|Gene Expression Regulation, Neoplastic|Head and Neck Neoplasms 118 CCL15 30979374 J. Exp. Clin. Cancer Res. 2019 PMC6461818 10.1186/s13046-019-1143-x 4 8 0 148 *Colorectal Cancer|SMAD4 protein, human|*Smad4 Protein|*Up-Regulation|*Ubiquitination|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Cell Movement|Biomarkers, Tumor|Cell Line, Tumor|Cell Proliferation|*Transcriptional Activation|*Colonic Neoplasms|Heterografts 118 CCL15 30943234 PLoS ONE 2019 PMC6447182 10.1371/journal.pone.0214674 3 5 0 148 *Vitreoretinopathy, Proliferative|*Retinal Detachment|Retinal Perforations|Vitreous Body|Cytokines|*Biomarkers|Enzyme-Linked Immunosorbent Assay|Upregulation 118 CCL15 30911832 Acta Diabetol 2019 10.1007/s00592-019-01317-6 1 0 0 148 Humans|*Vitreous Body|*Diabetic Retinopathy|*Chemokines|Enzyme-Linked Immunosorbent Assay|*Body Fluids|Diabetes Mellitus, Type 2 118 CCL15 30877129 Cancer Epidemiol. Biomarkers Prev. 2019 10.1158/1055-9965.EPI-18-1157 0 1 0 148 Humans|*Prospective Studies|*Cohort Studies|Japan|*Public Health|*Esophageal Cancers|*Stomach|Stomach Neoplasms|Case-Control Studies|Risk Factors|*Inflammation|*Biomarkers 118 CCL15 30867307 J. Virol. 2019 PMC6532071 10.1128/JVI.00242-19 0 2 0 148 *Receptors, CCR5|*Semen|HIV-1|Macrophage Inflammatory Proteins|Chemokine CCL4|Chemokine CCL3|Chemokine CCL5|CD4-Positive T-Lymphocytes|HIV Infections|CD8-Positive T-Lymphocytes|Chemokines, CC|Receptors, CXCR4|Virus Replication 118 CCL15 30595762 Dis. Markers 2019 PMC6282129 10.1155/2018/4949175 2 0 0 148 Female|Humans|*Smoke|*Biomass|*Chronic Obstructive Pulmonary Disease|*Tobacco|Spirometry|Forced Expiratory Volume|*Rural Population|Smoking|Environmental Exposure|Risk Factors|*Biomarkers 118 CCL8 31814701 Mol. Vis. 2019 PMC6857774 0 0 0 371 *Retinal Vein Occlusion|*Chemokines|Macular Edema|Vitreous Body|Vitrectomy|Vascular Endothelial Growth Factor A|*Ischemia 501 CCL8 31761882 J. Reprod. Dev. 2019 PMC7040214 10.1262/jrd.2019-113 0 1 0 371 Pregnancy|Cattle|Animals|Female|*Chemokines, C-C|*Placentomes|Parturition|Labor, Induced|Estrogens|Glucocorticoids|Prostaglandins|Betamethasone|Fetus|Triamcinolone Acetonide 501 CCNQ 31789883 Crit Care Nurs Q 2019 10.1097/CNQ.0000000000000296 0 0 0 37 Humans|*Central Venous Catheters|Catheter-Related Infections|Catheterization, Central Venous|Infection Control|Cross Infection|*Dressing|Guideline Adherence|Quality Improvement|*Burkitt Lymphoma 1015 CCNQ 31789882 Crit Care Nurs Q 2019 10.1097/CNQ.0000000000000295 0 0 0 37 Humans|United States|Aged|*Risk Factors|*Esophageal Cancer|*Lifestyle|Alcohol Drinking|Smoking|Carcinoma, Squamous Cell|Dietary Habits|Beverages|Diets|Coffee|Asian|Food|Tea|Case-Control Studies|Ethanol|*Complement Factor B|Obesity|Asia 1015 CCNQ 31789881 Crit Care Nurs Q 2019 10.1097/CNQ.0000000000000294 0 0 0 37 Adult|Humans|*Music Therapy|*Anxiety|*Pain Management|Pain|*Anxiety Disorders|Stress, Psychological|Inpatient 1015 CCNQ 31789880 Crit Care Nurs Q 2019 10.1097/CNQ.0000000000000293 1 0 0 37 Humans|*Compassion Fatigue|*Burnout, Professional|*Burnout|Job Satisfaction|Workplace|Nursing Staff, Hospital|Suffering|Empathy|Surveys and Questionnaires|Health Personnel 1015 cd248 31827490 Front Genet 2019 PMC6892359 10.3389/fgene.2019.01200 2 10 0 366 Humans|*RNA, Micro|Leukocytes, Mononuclear|Gene Expression Profiling|High-Throughput Nucleotide Sequencing|Transcriptome|Epigenetic|*Extremities, Lower 114 cd248 31746054 Mol. Carcinog. 2019 10.1002/mc.23137 1 2 0 366 Humans|*Down-Regulation|*Colorectal Cancer|*Cell Movement|5 Fluorouracil|Gene Expression Regulation, Neoplastic|HCT116 Cells|MicroRNAs|Epithelial-Mesenchymal Transition|CD248 protein, human|*Antigens, CD|Upregulation|Drug Resistance, Neoplasm|Cell Line, Tumor|*Toll-Like Receptor|*Colon Cancers|*Genes, Regulator 114 cd248 31287944 FEBS J. 2019 PMC6852297 10.1111/febs.14985 2 0 0 366 *Lectin, C-Type|Endothelial Cells|*Cancer|CD248 protein, human|Antigens, CD|Antigens, Neoplasm|Neovascularization, Pathologic|*Inflammation|THBD protein, human|Thrombomodulin|Membrane Glycoproteins|Pericytes|Cell Adhesion|Cell Surface Proteins|Protein Binding|Ligands 114 cd248 31257535 Mol Med Rep 2019 10.3892/mmr.2019.10429 1 0 0 366 *Myofibroblasts|Pathological Angiogenesis|Fibrosis|Antigens, Neoplasm|Signal Transduction|Antigens, CD|Cancers|Cells, Cultured|Liver 114 cd248 31221584 EBioMedicine 2019 PMC6606747 10.1016/j.ebiom.2019.05.057 1 0 0 366 *Adipose Tissue, White|*Adipocyte|*Inflammation|*Fibrosis|Insulin Resistance|Diet, High-Fat|Obesity|*Hypoxia|Energy Metabolism 114 cd248 31034598 Cancer 2019 PMC6618088 10.1002/cncr.32084 1 1 0 366 Humans|*Docetaxel|ontuxizumab|gemcitabine|*Antibodies, Monoclonal, Humanized|*Deoxycytidine|*Sarcoma|Soft Tissue Neoplasms|Taxoids|Disease-Free Survival|Antineoplastic Combined Chemotherapy Protocols|CD248 protein, human|Antigens, Neoplasm|Kaplan-Meier Estimate|Treatment Outcome|Antigens, CD 114 cd248 31013287 PLoS ONE 2019 PMC6478286 10.1371/journal.pone.0215301 0 0 0 366 *Frozen Shoulder|*Inflammation|Bursa, Synovial|Fibroblast 114 cd248 30986375 J. 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Dermatol. 2019 10.1016/j.jid.2019.03.1149 0 1 0 366 Mice|Animals|*Receptors, Platelet Derived Growth Factor|NIH 3T3 Cells|tumor endothelial marker 1, mouse|*Antigens, CD|CD248 protein, human|*Wound Healing|*Antigens, Neoplasm|Platelet-Derived Growth Factor BB|Neoplasm Proteins|Proto-Oncogene Proteins c-sis|Pericytes|Cell Proliferation|Fibroblasts|Collagen|Signal Transduction|Neoplasms 114 cd248 30847027 Oncotarget 2019 PMC6398180 10.18632/oncotarget.26590 4 18 0 366 CD248 protein, human|Antigens, Neoplasm|Antigens, CD|Pericyte|Antibody-Drug Conjugates|Sarcoma|Cell Line, Tumor|Flow Cytometry 114 cd248 30679663 Sci Rep 2019 PMC6345742 10.1038/s41598-018-37277-0 2 0 0 366 Humans|*Whole Exome Sequencing|*Pulmonary Arterial Hypertension|*Heritable Pulmonary Arterial Hypertension|BMPR2 protein, human|Bone Morphogenetic Protein Receptors, Type II|Mutations|Pulmonary Veno-Occlusive Disease|Exome|Hypertension, Pulmonary|Genetic Predisposition to Disease|Phenotype|Protein-Serine-Threonine Kinases|CD248 protein, human|Antigens, Neoplasm|Antigens, CD|ATP13A3 protein, human|Adenosine Triphosphatases|Membrane Transport Proteins 114 cd248 30623276 Invest New Drugs 2019 PMC6736902 10.1007/s10637-018-0713-7 0 0 0 366 Humans|Young Adult|Adult|ontuxizumab|Japan|Carcinoma, Hepatocellular|Liver Neoplasms|*Antibodies, Monoclonal, Humanized|CD248 protein, human|*Antigens, Neoplasm|*Antigens, CD|Maximum Tolerated Dose|Drug Resistance, Neoplasm|Kaplan-Meier Estimate|Cohort Studies|Gastric Cancer 114 cd276 31887631 Transl Oncol 2019 PMC6938869 10.1016/j.tranon.2019.11.006 0 0 0 847 Humans|Child|*Prognosis|B7 Antigens|Immunohistochemistry|*Central Nervous System Neoplasms|Antibody-Dependent Cell Cytotoxicity|Biomarkers|CD276 protein, human 364 cd276 31886324 Bone Rep 2019 PMC6921147 10.1016/j.bonr.2019.100237 1 0 0 847 Humans|*Monocytes|*Endocytosis|Clathrin|*Cell Differentiation|CAP18 lipopolysaccharide-binding protein|Antimicrobial Cationic Peptides|Endosomes|Osteocytes|*Receptors, Interleukin-8B|Membrane Microdomains|Transport Vesicles|Neutrophils|Lysosomes|Golgi Apparatus|HeLa Cells|CD276 protein, human|B7 Antigens 364 cd276 31819652 Cancer Manag Res 2019 PMC6899073 10.2147/CMAR.S222224 0 4 0 847 Humans|Female|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Drug Resistance, Neoplasm|*Signal Transduction|BCL2 protein, human|*Proto-Oncogene Proteins c-bcl-2|TOR Serine-Threonine Kinases|B7 Antigens|Ovarian Cancer|Cell Line, Tumor|Cell Proliferation|Carcinoma, Ovarian Epithelial|Apoptosis|Gene Expression Regulation, Neoplastic 364 cd276 31741193 Stem Cell Rev Rep 2019 10.1007/s12015-019-09907-1 1 0 0 847 Humans|*Wharton Jelly|*Mesenchymal Stem Cells|*Umbilical Cord|Cell Differentiation|Cell Proliferation|Lymphocyte Activation|Cells, Cultured|Cell Culture|Cytokines|Immune Tolerance|CD276 protein, human|B7 Antigens 364 cd276 31737785 Open Med (Wars) 2019 PMC6843478 10.1515/med-2019-0076 0 0 0 847 *Carcinoma, Non-Small-Cell Lung|*Prognosis|*Lung Neoplasms|Adenocarcinoma|Gene Expression Regulation, Neoplastic|*Transcription Factors|Kaplan-Meier Estimate 364 cd276 31731055 Mol. Immunol. 2019 10.1016/j.molimm.2019.10.026 1 10 0 847 *RNA, Long Noncoding|*Multiple Myeloma|*Macrophage Activation|*Macrophages|MicroRNAs|Gene Expression Regulation, Neoplastic|STAT3 Transcription Factor|Signal Transduction|Cell Proliferation|B7 Antigens|Cell Line, Tumor 364 CD5L 31883820 J. Heart Lung Transplant. 2019 10.1016/j.healun.2019.11.004 0 0 0 193 Heart Transplantation|Graft Rejection|*Heart|Biopsy|*Plasma 98 CD5L 31669066 J. Diabetes Complicat. 2019 10.1016/j.jdiacomp.2019.07.003 0 0 0 193 *Diabetes Mellitus, Type 2|*Kidney|Diabetic Nephropathies|Glomerular Filtration Rate|*Biomarkers|Renal Insufficiency, Chronic|Cohort Studies|Prognosis|Disease Progression|Risk Factors 98 CD5L 31302940 J. Leukoc. Biol. 2019 PMC6803036 10.1002/JLB.3RI0519-161R 0 1 0 193 secretory IgM|*Immunoglobulin M|Cells, B-1|Lymphocyte Activation|Homeostasis|Spleen|Cell Differentiation 98 CD5L 31279222 Redox Biol 2019 PMC6612658 10.1016/j.redox.2019.101264 1 4 0 193 Airborne Particulate Matter|Air Pollutants|Lung Injury|Particle Size|Lung|Oxidative Stress 98 CD5L 31154043 Chest 2019 10.1016/j.chest.2019.04.134 1 0 0 193 Humans|*Critical Illness|*Sepsis|*Biomarkers|Organ Dysfunction Scores|Calcitonin|ROC Curve|Intensive Care Units|Prognosis|Case-Control Studies|*Macrophage|Apoptosis 98 CD5L 31076347 EBioMedicine 2019 PMC6558273 10.1016/j.ebiom.2019.04.052 1 1 0 193 Animals|*Fibrosis, Liver|Hepatic Stellate Cells|Liver|Chemical and Drug Induced Liver Injury|*Liver Diseases|Signal Transduction|Cells, Cultured|Disease Models, Animal|Inflammation 98 CD5L 30959370 Int. Immunopharmacol. 2019 10.1016/j.intimp.2019.03.057 0 0 0 193 Humans|Mice|Animals|*Methicillin-Resistant Staphylococcus aureus|*Methicillin|Staphylococcus aureus|*Pneumonia, Staphylococcal|Lungs|Cytokines|Chemokines|Immunologic Factors|Cd5l protein, mouse|Receptors, Immunologic|Apoptosis Regulatory Proteins 98 CD5L 30850364 Cancer Genomics Proteomics 2019 PMC6489687 10.21873/cgp.20118 3 0 0 193 Male|*Proteomics|Electrophoresis, Gel, Two-Dimensional|Proteome|Neoplasm Proteins|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Biomarkers, Tumor|Blood Proteins 98 CD5L 30772974 Zhonghua Yi Xue Za Zhi 2019 10.3760/cma.j.issn.0376-2491.2019.05.005 0 0 0 193 98 CD5L 30755830 PeerJ 2019 PMC6368834 10.7717/peerj.6375 7 1 0 193 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Computational Biology|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Biomarkers, Tumor|Protein Interaction Maps|Databases, Genetic|Disease Progression 98 CDCA7 31724723 Essays Biochem. 2019 PMC6923317 10.1042/EBC20190035 1 0 0 92 Humans|Animals|*DNA Methylation|*B-DNA|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|*Immunologic Deficiency Syndromes|*Centromeres|CDCA7 protein, human|Nuclear Proteins|Immunodeficiency syndrome, variable|*Face|DNA Helicases|Primary Immunodeficiency Diseases|*Abnormalities, Multiple|Repressor Proteins|Epigenesis, Genetic|Mutations|Genes, cdc|HELLS protein, human 50 CDCA7 31570276 Pathol. 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Pract. 2019 10.1016/j.prp.2019.152559 1 2 0 92 *Lung Adenocarcinoma|*Cell Cycle|Cell Proliferation|Lung Neoplasms|Prognosis|Biomarkers, Tumor|Apoptosis|CDCA7 protein, human|*Nuclear Proteins|Cell Movement|Cell Line, Tumor|Immunohistochemistry|*Cell Division|Up-Regulation 50 CDCA7 31561277 Genes Cells 2019 10.1111/gtc.12723 0 1 0 92 Humans|Mice|Animals|*Heterochromatin|*Transcriptional Activation|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|CDCA7 protein, human|Nuclear Proteins|Immunologic Deficiency Syndromes|Zinc Finger|Centromeres|Immunodeficiency syndrome, variable|Primary Immunodeficiency Diseases|Repressor Proteins|DNA Helicases|DNA Methylation|Promoter Regions, Genetic|Transcription Factor|Mutations|Protein Binding 50 CDCA7 31489115 Oncotarget 2019 PMC6707948 10.18632/oncotarget.27120 0 0 0 92 *Hypereosinophilic Syndrome|Sezary Syndrome|*Transcriptome Analysis|Cutaneous T Cell Lymphoma|CD3 Complex|CD4-Positive T-Lymphocytes|Flow Cytometry|Transcriptome Profiles|Skin Neoplasms|Skin 50 CDCA7 31476899 Autoimmunity 2019 10.1080/08916934.2019.1657846 0 0 0 92 *DNA Methylation|*Immunologic Deficiency Syndromes|*Centromeres|*Mutations|DNA (Cytosine-5-)-Methyltransferases|*Abnormalities, Multiple|*Face|DNA Helicases|Repressor Proteins|Nuclear Proteins|Primary Immunodeficiency Diseases|*Musculoskeletal Abnormalities|*Chromosome Structures 50 CDCA7 31332696 In Vitro Cell. 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Anim. 2019 10.1007/s11626-019-00376-x 6 7 0 92 Humans|*RNA, Long Noncoding|*Upregulation|*Cell Proliferation|*Colorectal Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Neoplasm Invasiveness|*Colonic Neoplasms|Cell Movement|Apoptosis|Cell Line, Tumor|CDCA7 protein, human|*Nuclear Proteins|FGD5 protein, human|Guanine Nucleotide Exchange Factors 50 CDCA7 31226215 Nucleic Acids Res. 2019 PMC6895263 10.1093/nar/gkz557 4 0 0 92 Mice|Animals|*Transcription Factor|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|CDCA7 protein, human|Nuclear Proteins|DNA Methylation|Immunologic Deficiency Syndromes|Zinc Fingers|Repressor Proteins|Immunodeficiency syndrome, variable|Primary Immunodeficiency Diseases|DNA Helicases|Centromeres|Mutations|Gene Activation|Face|*Gene Expression Regulation|Mutations, Missense 50 CDCA7 31221787 Haematologica 2019 PMC7049348 10.3324/haematol.2018.215459 2 1 0 92 Mice|Animals|CDCA7 protein, human|*Nuclear Proteins|*Cytoskeleton|Cell Migration|*Lymphoma|*Neoplastic Processes|Cancer|Carcinogenesis|Actins|Cell Adhesion|Actin Cytoskeleton|Actomyosin|matrigel|Laminin|Proteoglycans|*Microtubules|Collagen|Drug Combinations 50 CDCA7 31030944 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.04.147 0 7 0 92 Humans|*T Cells|CDCA7 protein, human|*Nuclear Proteins|Immunologic Deficiency Syndromes|Repressor Proteins|DNA (Cytosine-5-)-Methyltransferases|DNA Helicases|Transcription Factors|*Genes, cdc|Centromeres|Mutations|DNA Methylation|*Apoptosis|Face|Primary Immunodeficiency Diseases|Transcriptional Activation|Nonsense Mutations|B-Lymphocytes 50 CDCA7 30765770 Sci Rep 2019 PMC6376004 10.1038/s41598-019-38546-2 8 0 0 92 Humans|*Mesenchymal Stem Cells|*Cellular Senescence|Osteogenesis|Cell Differentiation|Adipogenesis|Cell Proliferation|*Biomarkers|Cells, Cultured|GLB1 protein, human|beta-Galactosidase 50 CDH19 31743516 J. Clin. Lab. Anal. 2019 PMC7083487 10.1002/jcla.23102 2 1 0 36 *Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Apoptosis|Transcriptome Profiling|Signal Transduction|*Neoplasms, Squamous Cell|Epulis|Proto-Oncogene Proteins c-bcl-2 25 CDH19 31133085 Animal 2019 10.1017/S1751731119000910 0 0 0 36 Swine|Animals|*Genome-Wide Association Study|*Phenotype|Genotype|Quantitative Trait Loci|Sus scrofa|Breeding|Single Nucleotide Polymorphisms|Genomics|Hybridization, Genetic|Weight Gain 25 CDH19 30710169 Virchows Arch. 2019 10.1007/s00428-018-02516-2 2 0 0 36 Humans|Female|*Endometrial Carcinoma|Carcinoma, Endometrioid|Cystadenocarcinoma, Serous|Adenocarcinoma, Clear Cell|SMARCA4 protein, human|Nuclear Proteins|Transcription Factors|Mutation|PTEN protein, human|PTEN Phosphohydrolase|DNA Mutational Analysis|Genes, Regulator|ARID1A protein, human|Immunohistochemistry|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Microsatellite Instability|Oncogenes 25 CDH22 31041846 Stem Cells 2019 10.1002/stem.3030 2 14 0 30 Male|Female|Mice|Animals|*Glial Derived Neurotrophic Factor Receptor 1|*Oogonial Stem Cells|GDNF protein, human|*Glial Cell Line-Derived Neurotrophic Factor|*Signal Pathways|Spermatogonia|Stem Cells|*Cell Line|Adult Germline Stem Cells|Cell Proliferation|Transcription Factors|src-Family Kinases|Testis|Cells, Cultured|Upregulation|Cadherins|Cdh22 protein, mouse 26 CDH22 31036200 Talanta 2019 10.1016/j.talanta.2019.03.082 1 1 0 30 *Electrode|Antibodies, Immobilized|Spectroscopy, Electrochemical Impedance|Electrochemical Techniques|Immunoassay|Limit of Detection|Biosensing Techniques|*Cadherins|*Thiophenes|Polymer|*Complement Factor B|Cancer Biomarkers|*Poly A|Atomic Force Microscopy 26 CDHR1 31387115 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.18-26415 0 0 0 33 Humans|*Silent Mutation|*Macula Lutea|Retinal Dystrophy|*Phenotype|Electroretinography|*Exon|Fluorescein Angiography|Genes, Recessive|DNA Mutational Analysis|Retina|Homozygote|Pedigree|Tomography, Optical Coherence|Visual Acuity|*Reading Frames|Mutation|CDHR1 protein, human|Nerve Tissue Proteins 34 CDHR1 31136651 Invest. Ophthalmol. Vis. Sci. 2019 PMC6538366 10.1167/iovs.19-26993 1 2 0 33 Humans|*Cone-Rod Dystrophies|*Retinitis Pigmentosa|Electroretinography|Retinal Rod Photoreceptor Cells|Retinal Cone Photoreceptor Cells|Genes, Recessive|Tomography, Optical Coherence|Visual Acuity|Pedigree|Phenotype|PROM1 protein, human|AC133 Antigen 34 CDHR1 30992995 Hum Genome Var 2019 PMC6459921 10.1038/s41439-019-0048-8 0 0 0 33 *Cone-Rod Dystrophies|Japan|Retinitis Pigmentosa|DNA Mutational Analysis|Electroretinography|Pedigree|Exome|Homozygote|Mutation|Frameshift Mutation 34 CDKL2 30953292 Virol Sin 2019 PMC6599507 10.1007/s12250-019-00101-8 1 2 0 100 Humans|*Herpesvirus 2, Human|*miRNA|*Actinomycin D|*HeLa Cells|Gene Expression Regulation, Viral|Virus Latency|*Apoptosis|3' Untranslated Region|Herpes Simplex|*Genes, p16|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|RNA, Viral|Viral Proteins|Cell Cycle 20 CDKL2 30786922 Clin Epigenetics 2019 PMC6381754 10.1186/s13148-019-0626-0 2 7 0 100 Humans|*Neoadjuvant Therapy|*Triple-Negative Breast Cancer|Taxoids|Antineoplastic Combined Chemotherapy Protocols|Docetaxel|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Cyclophosphamide|*Epigenetic|Epigenesis, Genetic 20 CDNF 31783118 Neurobiol. Dis. 2019 PMC7000201 10.1016/j.nbd.2019.104696 1 0 0 99 Mice|Animals|*Neurons, Dopamine|*Dopamine|Oxidopamine|Substantia Nigra|Corpus Striatum|Parkinson Disease|Nerve Growth Factors|Neuroprotective Agents|Disease Models, Animal|Motor Activity 99 CDNF 31781038 Front Endocrinol (Lausanne) 2019 PMC6851024 10.3389/fendo.2019.00765 2 2 0 99 Male|Mice|Animals|*Astrocytes|enovin|*Nerve Growth Factors|NTF3 protein, human|*Mesencephalon|Endoplasmic Reticulum Stress|Unfolded Protein Response|Neurons|Neurodegenerative Diseases|Homeostasis|Cell Survival|MANF protein, mouse 99 CDNF 31744764 J Stroke Cerebrovasc Dis 2019 10.1016/j.jstrokecerebrovasdis.2019.104502 0 0 0 99 Humans|*Blood Platelets|*Dopamine|*Stroke|Nerve Growth Factors|Case-Control Studies 99 CDNF 31591054 Pathol. Res. Pract. 2019 10.1016/j.prp.2019.152510 1 0 0 99 *Carcinoma, Hepatocellular|*Liver Cancer|Diabetes Mellitus, Type 2|Protein Interaction Maps|Bioinformatic|Gene Regulatory Networks|Gene Expression Profiling|Gene Ontology|Gene Expression Regulation, Neoplastic|Databases, Genetic|Biomarkers, Tumor|Software|Survival Analysis 99 CDNF 31555085 Front Neurosci 2019 PMC6737037 10.3389/fnins.2019.00929 0 2 0 99 Humans|Animals|*Parkinson Disease|*Astrocytes|enovin|*Nerve Growth Factors|NTF3 protein, human|*Mesencephalon|Neurons, Dopamine 99 CDNF 31244598 Front Neurosci 2019 PMC6580362 10.3389/fnins.2019.00590 0 0 0 99 Humans|Male|Rats|Animals|*Dopamine|*Rats, Wistar|*Substantia Nigra|6 Hydroxydopamine|CDNF protein, human|Nerve Growth Factors|Corpus Striatum|Neurons, Dopamine|Tyrosine Hydroxylase|Parkinson Disease|*Brainstem|Neuroprotective Agents|Brain|Motor Activity 99 CDNF 31195344 Pharmacol Rep 2019 10.1016/j.pharep.2019.03.005 1 0 0 99 Humans|Female|Animals|Rats|BDNF protein, human|*Brain-Derived Neurotrophic Factor|GDNF protein, human|*Glial Cell Line-Derived Neurotrophic Factor|*Proof of Concept Study|*Smell|Olfactory Bulb|Depression|Disease Models, Animal|*Administration, Oral 99 CDNF 31105589 Front Physiol 2019 PMC6499070 10.3389/fphys.2019.00486 9 0 0 99 Neurons|Parkinson Disease|Glial Cell Line-Derived Neurotrophic Factor|*Cells, Glial|Astrocytes|Microglia|*Central Nervous System|Neuroprotective Agents|Cells, Cultured|Cell Death|Media, Conditioned 99 CDNF 31100327 Life Sci. 2019 10.1016/j.lfs.2019.05.036 0 2 0 99 Rats|Animals|*Neuroprotection|CDNF protein, rat|6 Hydroxydopamine|Corpus Striatum|Parkinson Disease|*Running|Dopamine|Tyrosine 3-Monooxygenase|*Exercise Test|Motor Activity|Brain-Derived Neurotrophic Factor|Disease Models, Animal 99 CDNF 31044581 Croat. 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J. 2019 PMC6509620 0 0 0 99 *Astrocytes|*Dopamine|enovin|*Neurotrophic Proteins|NTF3 protein, human|*Endoplasmic Reticulum|*Mesencephalon|Neurons|*Neuroprotection|Endoplasmic Reticulum Stress|Thapsigargin|Parkinson Disease|Models, Neurological|Brain 99 CDNF 31037983 Cell Transplant 2019 PMC6628565 10.1177/0963689719837915 1 0 0 99 Male|Rats|Animals|*Astrocyte|*Stroke|*Thalamus|enovin|*Neurotrophic Protein|NTF3 protein, human|Intracranial Hemorrhages|Rats, Sprague-Dawley|Hyperalgesia|Pain|*Mesencephalon|*Cerebral Infarction|Disease Models, Animal|Recovery of Function|CDNF protein, rat 99 CDNF 31033033 Brain Pathol. 2019 10.1111/bpa.12730 1 0 0 99 Humans|Parkinson Disease 10|*Parkinson Disease|*Dopamine|*Fibroblast Growth Factor 2|GDNF protein, human|*Glial Cell Line-Derived Neurotrophic Factor|enovin|Substantia Nigra|*Hippocampus|NTF3 protein, human|Corpus Striatum|BDNF protein, human|Brain-Derived Neurotrophic Factor|Neurons|Mesencephalon|Brain 99 CDNF 30956647 EXCLI J 2019 PMC6449669 0 0 0 99 Male|Rats|Animals|*Parkinson Disease|*Dopamine|*Rats, Wistar|6 Hydroxydopamine|*Neural Stem Cells|*Cell Movement|Corpus Striatum|Bromodeoxyuridine|Nerve Growth Factors|Subventricular Zone|Cell Differentiation|*Neurogenesis|Neurons|Cell Proliferation|Disease Models, Animal 99 CDNF 30947516 Cell Transplant 2019 PMC6628563 10.1177/0963689719840290 3 0 0 99 Animals|Humans|*Parkinson Disease|enovin|CDNF protein, human|NTF3 protein, human|GDNF protein, human|Glial Cell Line-Derived Neurotrophic Factor|NRTN protein, human|Neurturin|Oxidopamine|TYRP1 protein, human|Neurons|*Membrane Glycoproteins|Neuroprotective Agents|Endoplasmic Reticulum Stress|Neurodegenerative Diseases|Unfolded Protein Response|Endoplasmic Reticulum 99 CDNF 30841717 Cell Transplant 2019 PMC6628564 10.1177/0963689719827943 2 0 0 99 Animals|Humans|*Cells, Cultured|Neurons|Nerve Growth Factors|Endoplasmic Reticulum Stress|Endoplasmic Reticulum|*Clones|Brain|*Cell Therapy 99 CDY1 31494467 Eur J Med Chem 2019 10.1016/j.ejmech.2019.111656 1 0 0 6 Animals|Molecular Docking Simulation|Histone|Protein Processing, Post-Translational|Histone Acetyltransferases|Co-Repressor Proteins|Small Molecule Libraries 54 CDY1 30787516 J Hum Reprod Sci 2019 PMC6333031 10.4103/jhrs.JHRS_12_18 0 0 0 6 Humans|Male|Male sterility due to Y-chromosome deletions|Hungary|*Chromosomes, Human, Y|*Infertility, Male|*Sex Chromosome Aberrations|*Sex Chromosome Disorders of Sex Development|*Chromosome Deletion|Oligospermia|Azoospermia|Seminal Plasma Proteins|Haplotypes|Spermatogenesis|Genetic Loci|Case-Control Studies 54 CEBPE 31867206 Leuk Res Rep 2019 PMC6906641 10.1016/j.lrr.2019.100188 1 0 0 172 Genetic Predisposition to Disease|Ikaros Transcription Factor|Polymorphism, Single Nucleotide|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Alleles|Genotype|CCAAT-Enhancer-Binding Proteins|Case-Control Studies|Brazil 144 CEBPE 31780527 Ann. Rheum. Dis. 2019 PMC7025734 10.1136/annrheumdis-2019-215782 0 1 0 172 *Transcriptome|Hematopoietic Stem Cells|Lineages, Cell|Granulocytes|Cell Differentiation|*Lupus Erythematosus, Systemic|Flow Cytometry|Cells, Cultured|Cell Count|Hematopoietic Stem Cell Transplantation 144 CEBPE 31350265 Blood 2019 PMC6788009 10.1182/blood.2018890764 3 0 0 172 Child|Humans|*Genetic Predisposition to Disease|Genome-Wide Association Study|*Down Syndrome|*Acute Lymphoblastic Leukemia|Ikaros Transcription Factor|Alleles|Frequencies, Allele|Polymorphism, Single Nucleotide|CCAAT-Enhancer-Binding Proteins|Genotype|Genetic Variation|Case-Control Studies|Cyclin-Dependent Kinase Inhibitor p16|Odds Ratio|1-phosphatidylinositol-4-phosphate 5-kinase|Phosphotransferases (Alcohol Group Acceptor)|Genes, p16|ARID5B protein, human 144 CEBPE 31256937 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.06.130 0 0 0 172 Humans|Specific Granule Deficiency|HDAC1 protein, human|*Histone Deacetylase 1|*Neutrophils|trichostatin A|CEBPE protein, human|*CCAAT-Enhancer-Binding Proteins|*Leukocyte Disorders|*Hydroxamic Acids|Transcription Factors|GATA1 protein, human|GATA1 Transcription Factor|Lactoferrin|Gene Expression Regulation|Eosinophil Major Basic Protein|Trans-Activators|Eosinophils|Homozygote 144 CEBPE 31201888 J. Allergy Clin. Immunol. 2019 10.1016/j.jaci.2019.06.003 1 0 0 172 *Gain of Function Mutation|CEBPE protein, human|CCAAT-Enhancer-Binding Proteins|NLR Family, Pyrin Domain-Containing 3 Protein|Leukocyte Disorders|Inflammasomes|Neutrophils|*Mutation|Transcription Factor|Gene Expression Regulation 144 CEBPE 31164135 J Transl Med 2019 PMC6549322 10.1186/s12967-019-1944-x 2 1 0 172 Humans|*Prognosis|*Leukemia, Myeloid, Acute|CCAAT-Enhancer-Binding Proteins|Gene Expression Regulation, Leukemic|Cytogenetic Analysis|Disease-Free Survival|Transplantation, Homologous|Karyotyping|Risk Factors|Mutation|Recurrence|CEBPE protein, human 144 CEBPE 30952671 Blood 2019 10.1182/blood.2018886077 0 1 0 172 *CCAAT Enhancer Binding Protein|*Leukopoiesis|Transcription Factor|Granulocytes|Myelopoiesis|Gene Expression Regulation|Cell Lineage|Cell Differentiation|Enhancer Elements, Genetic|Myeloid Cells|Cell Line 144 CECR2 31730617 PLoS Negl Trop Dis 2019 PMC6881072 10.1371/journal.pntd.0007693 2 0 0 63 Humans|Animals|*Lead|*Drug Repositioning|Prasiquantel|Schistosoma mansoni|Schistosomiasis mansoni|Anthelmintics|Schistosomiasis|*Schistosomatidae|*Epigenetic|Life Cycle|Computational Biology|Epigenesis, Genetic 32 CECR2 30624862 ChemMedChem 2019 10.1002/cmdc.201800738 0 0 0 63 Humans|*Protein Domains|Nuclear Proteins|Transcription Factors|Cell Cycle Proteins|Models, Molecular 32 CELF2 31729991 BMC Med Genomics 2019 PMC6858651 10.1186/s12920-019-0603-7 0 0 0 220 *Prognosis|*Alternative Splicing|*Glioma|Brain Neoplasms|Glioblastoma|Isocitrate Dehydrogenase|Neoplasm Grading|Gene Expression Regulation, Neoplastic|DNA Methylation|Kaplan-Meier Estimate|Biomarkers, Tumor|Mutation 85 CELF2 31509743 Cell Rep 2019 PMC6752737 10.1016/j.celrep.2019.08.022 1 0 0 220 Humans|*Polyadenylation|3' UTRs|*RNA Binding Protein|mRNA|TYRP1 protein, human|*Membrane Glycoproteins|Gene Expression Regulation|Cell Line, Tumor|Transcriptome|Signal Transduction|CELF2 protein, human|CELF Proteins|Nerve Tissue Proteins 85 CELF2 31409895 Oncogene 2019 10.1038/s41388-019-0936-x 1 0 0 220 Humans|*RNA Binding Protein|CELF Proteins|*RNA, Messenger, Splicing|DNA Methylation|Alternative Splicing|Gene Expression Regulation, Neoplastic|Nerve Tissue Proteins|Down-Regulation|Promoter Regions, Genetic|Cell Line, Tumor|*Epigenetic|Protein Isoforms|Epigenesis, Genetic|CELF2 protein, human 85 CELF2 31241130 Carcinogenesis 2019 PMC7221505 10.1093/carcin/bgz113 0 13 0 220 Humans|PTEN protein, human|*PTEN Phosphohydrolase|Phosphatidylinositol 3-Kinases|*Lung Carcinoma, Non-Small-Cell|*Guanine Nucleotide Exchange Factor|Proto-Oncogene Proteins c-akt|Signal Transduction|Phosphoinositide 3 Kinase|Cell Proliferation|Phosphorylation|Apoptosis|Glioma|Downregulation|Lung Neoplasms|*RNA Binding Protein|CELF2 protein, human|CELF Proteins|Nerve Tissue Proteins 85 CELF2 31020708 Mol. Carcinog. 2019 PMC6602857 10.1002/mc.23023 2 5 0 220 Humans|*Autophagy|*RNA Binding Protein|CELF Proteins|Beclin 1|Autophagy-Related Protein 5|siRNA|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Autophagosomes|Colorectal Cancer|Apoptosis|RNA Stability|Nerve Tissue Proteins|CELF2 protein, human 85 CELF2 30859622 Genet. Epidemiol. 2019 10.1002/gepi.22198 1 0 0 220 *Genome-Wide Association Study|Epistasis, Genetic|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Regulatory Networks|Colorectal Cancer 85 CELF4 31425505 PLoS Comput. Biol. 2019 PMC6716675 10.1371/journal.pcbi.1007227 0 1 0 34 Humans|Mice|Animals|*Chromatin Immunoprecipitation Sequencing|*RNA-Binding Proteins|Immunoprecipitation|Sequence Analysis, RNA|RNA|Transcriptome|Binding Sites|High-Throughput Nucleotide Sequencing|mRNA|Gene Expression Regulation 43 CELF4 31148553 Int J Oral Sci 2019 PMC6544625 10.1038/s41368-019-0051-4 0 1 0 34 Child|Humans|Adolescent|*Streptococcus mutans|*Genome-Wide Association Study|Dental Caries|DMF Index|*Primary Dentition|Saliva|Colony Count, Microbial|Tooth Loss|Appalachia|Iowa|GALK2 protein, human|Galactokinase 43 CELF4 30903111 Eur. J. Hum. Genet. 2019 PMC6777610 10.1038/s41431-019-0382-9 3 0 0 34 Humans|Mice|Animals|*Haploinsufficiency|Genome-Wide Association Study|*Hypertension|Blood Pressure|GTPase-Activating Proteins|Translocation, Genetic|Obesity|Body Mass Index|Heterozygote 43 CELSR2 31787999 Front Genet 2019 PMC6854026 10.3389/fgene.2019.00909 1 0 0 105 Humans|Female|Endometrial Cancer|NF-kappa B|Signal Transduction|*Mutations|Prognosis|Gene Expression Regulation, Neoplastic 106 CELSR2 31664505 Acta Neuropathol. 2019 PMC7243727 10.1007/s00401-019-02086-w 0 1 0 105 Humans|Mice|Animals|ATM protein, human|*Ataxia Telangiectasia Mutated Proteins|*Neurofibroma|Plexiform Neurofibroma|Neurofibromatosis Type I|Neurofibromin 1|NFIB protein, human|*NFI Transcription Factors|*Mutation, Missense|Mutation|Neurofibromatoses|Celsr2 protein, mouse|Cadherins 106 CELSR2 31249592 Front Genet 2019 PMC6584752 10.3389/fgene.2019.00540 0 5 0 105 Humans|Pregnancy|Female|Infant, Newborn|*Lipid Metabolism|*Circadian Clocks|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Triglycerides|Cholesterol, LDL|Lipids|Preterm Birth 106 CELSR2 30911093 J. Hum. Genet. 2019 10.1038/s10038-019-0591-7 2 0 0 105 Humans|*Genome-Wide Association Study|*Asian Continental Ancestry Group|Triglycerides|*Lipids|Cholesterol, HDL|Cholesterol, LDL|Polymorphism, Single Nucleotide|European Continental Ancestry Group|Quantitative Trait Loci|Lipid Metabolism|DNA Methylation|Regulatory Sequences, Nucleic Acid|Phenotype|BUD13 homolog protein, human|RNA-Binding Proteins|REEP3 protein, human|Membrane Transport Proteins 106 CELSR2 30740535 Wellcome Open Res 2019 PMC6348437 10.12688/wellcomeopenres.14788.2 3 1 0 105 106 celsr3 31855460 DNA Cell Biol. 2019 10.1089/dna.2019.4746 0 0 0 177 Humans|*Whole Exome Sequencing|*Tourette Syndrome|*Chinese|Genetic Predisposition to Disease|Genetic Variation|Mutation 78 celsr3 31608178 PeerJ 2019 PMC6786253 10.7717/peerj.7816 2 0 0 177 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Prognosis|EGFR protein, human|*Receptor, EGF|Gene Expression Regulation, Neoplastic|*Cadherin 3|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate|ROC Curve|RNA, Messenger|Celsr3 protein, human|Receptors, Cell Surface 78 celsr3 31515243 Pharmacol. Rev. 2019 PMC6742926 10.1124/pr.119.018044 1 8 0 177 United States|ADGRE5 protein, human|G-Protein-Coupled Receptors|*Ligands|metabotropic glutamate receptor 8|Receptors, Metabotropic Glutamate|ADGRG1 protein, human|metabotropic glutamate receptor 7|metabotropic glutamate receptor 6|*Cell Membrane|metabotropic glutamate receptor 4|Binding Sites|Signal Transduction|Models, Molecular|Antigens, CD 78 celsr3 31298263 Cereb. Cortex 2019 10.1093/cercor/bhz136 0 0 0 177 Humans|Mice|Animals|Infant|*Neurons|*Prosencephalon|Thalamus|Axons|Telencephalon|Cerebral Cortex|*Embryo, Mammalian|Neural Pathways|Nerve Tissue Proteins|Cell Differentiation|Celsr3 protein, mouse|Receptors, Cell Surface|Cadherins 78 celsr3 31149640 Commun Biol 2019 PMC6531543 10.1038/s42003-019-0434-2 2 2 0 177 Animals|*Zebrafish|*Ubiquitin|*Axons|Zebrafish Proteins|Nerve Regeneration|Spinal Cord Injuries|Spinal Cord|Motor Neurons|Recovery of Function|Axon Outgrowth|Disease Models, Animal|Signal Transduction|*Ligases 78 celsr3 30886579 Front Pharmacol 2019 PMC6409312 10.3389/fphar.2019.00150 5 5 0 177 Humans|*RNA, Long Noncoding|*Squamous Cell Carcinoma of Head and Neck|*Prognosis|MIRN99 microRNA, human|miRNA|MIRN137 microRNA, human|mRNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Bioinformatics|Kaplan-Meier Estimate|Head and Neck Neoplasms|NOSTRIN protein, human|Intracellular Signaling Peptides and Proteins|HOXB9 protein, human|Homeodomain Proteins 78 celsr3 30758284 Elife 2019 PMC6395066 10.7554/eLife.42143 2 15 0 177 Animals|*Axon Guidance|*Dystroglycans|Axons|Neurogenesis|Spinal Cord|Brain 78 celsr3 30729033 NPJ Genom Med 2019 PMC6358616 10.1038/s41525-019-0077-8 5 0 0 177 Humans|*DNA Methylation|*Cancers|CpG Islands|Genome, Human|Epigenesis, Genetic|Oligonucleotide Array Sequence Analysis|Genomics|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Signal Transduction|*Biochemical Phenomena|TRIM59 protein, human|Membrane Proteins|Metalloproteins 78 celsr3 30696738 mBio 2019 PMC6355981 10.1128/mBio.02687-18 12 8 0 177 Humans|Female|*Human Papilloma Virus|*Papillomavirus Infections|HPV 16|Papillomavirus E7 Proteins|Oncogene Proteins, Viral|Human papillomavirus 18|Cervical Cancer|NOVA1 protein, human|*RNA-Binding Proteins|Repressor Proteins|DNA-Binding Proteins|Transcriptome Analyses|RNA, Messenger|Carcinogenesis|Cell Line, Tumor|Keratinocytes|DNA Replication|KHSRP protein, human 78 CEND1 31191667 Stem Cells Int 2019 PMC6525816 10.1155/2019/2054783 1 1 0 30 NEUROG1 protein, human|Nerve Tissue Proteins|Cell Differentiation|Neurons|*Neural Stem Cells|Cell Cycle|Neurogenesis|Ran binding protein 9|Cytoskeletal Proteins|Membrane Proteins|Nuclear Proteins|*Brain|Adaptor Proteins, Signal Transducing|CCND1 protein, human|Cyclin D1|Nervous System|Signal Transduction|*Cell Division 26 CEND1 31079319 Neurosci Bull 2019 PMC6864003 10.1007/s12264-019-00386-5 0 0 0 30 Pregnancy|Female|Mice|Animals|Swine|*Drosophila|Drosophila melanogaster|Cell Differentiation|Neurons|Nerve Tissue Proteins|Cell Cycle|Neurogenesis|Membrane Proteins|Mother Cells|Cell Proliferation|*Mammals|Nervous System|Signal Transduction|Cend1 protein, mouse 26 CEND1 30760981 Front Cell Neurosci 2019 PMC6361865 10.3389/fncel.2018.00497 2 0 0 30 Animals|Mice|Neurons|*Anxiety|*Cognitive Function|Cell Differentiation|Nerve Tissue Proteins|*Brain|Membrane Proteins|Cell Cycle|Cend1 protein, mouse 26 cenpb 31324812 Nat Commun 2019 PMC6642174 10.1038/s41467-019-11162-4 22 3 0 198 Humans|*Upregulation|*Carcinoma, Squamous Cell|miRNA|mRNA|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|*Disease Progression|Cell Proliferation|*Transcriptional Activation|*Carcinoma, Non-Small-Cell Lung|Cell Line, Tumor|Computational Biology|circRNA|Lung Neoplasms|FOXM1 protein, human|Forkhead Box Protein M1|MIRN873 microRNA, human 183 cenpb 30685360 Clin. Chim. Acta 2019 10.1016/j.cca.2019.01.020 1 0 0 198 Humans|*Autoantibodies|*Sclerosis, Systemic|Autoantigens|*Immunoassay|Centromere Protein A|Chromosomal Proteins, Non-Histone|*Immunologic Tests|*Asian Continental Ancestry Group 183 CES1P1 31882500 In Vivo 2019 PMC6984093 10.21873/invivo.11782 0 0 0 5 Humans|*Twins, Monozygotic|*DNA Methylation|*B-DNA|CpG Islands|Epigenesis, Genetic|Promoter Regions, Genetic|Genome, Human|Phenotype|Genetic Predisposition to Disease|*Myocardial Infarction 20 CES1P1 31356197 Cancer Biomark 2019 10.3233/CBM-190215 1 1 0 5 *RNA, Long Noncoding|*Leukemia, Myeloid, Acute|*Sequencing, RNA|*Whole Exome Sequencing|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|*Base Sequence 20 CFDP1 31507454 Front Physiol 2019 PMC6713933 10.3389/fphys.2019.01093 0 0 0 43 Animals|Drosophila Proteins|Drosophila melanogaster|Phosphoproteins|Carrier Proteins|Protein Binding|Amino Acid Sequence 40 chd2 31872862 J. Clin. Endocrinol. Metab. 2019 10.1210/clinem/dgz192 0 0 0 105 Humans|*Obesity|Basic Helix-Loop-Helix Transcription Factors|Prader-Willi Syndrome|Genetic Association Studies|Repressor Proteins|Phenotype|Haploinsufficiency|SIM1 protein, human 145 chd2 31865343 Horm Res Paediatr 2019 PMC7173346 10.1159/000504884 0 0 0 105 Child|Humans|IGF1 protein, human|*Insulin-Like Growth Factor I|*Electronic Health Records|*Dwarfism|Growth Disorders|Human Growth Hormone|*Genomics|Receptor, IGF Type 1 145 chd2 31774495 Blood 2019 PMC7059458 10.1182/blood.2019001904 1 0 0 105 Humans|*Lymphoma, Large-Cell, Anaplastic|*Breast Implants|Phosphatidylinositol 3-Kinases|*Breast Implantation|STAT3 protein, human|STAT3 Transcription Factor|*Signal Transduction|Janus Kinases|JAK1 protein, human|Janus Kinase 1|Mutations|STAT5B protein, human|STAT5 Transcription Factor|KMT2D protein, human|DNA-Binding Proteins|Neoplasm Proteins|Suppressor of Cytokine Signaling Proteins|KMT2C protein, human 145 chd2 31704914 Nat Commun 2019 PMC6841665 10.1038/s41467-019-13075-8 1 0 0 105 Animals|Mice|*RNA, Long Noncoding|Chromatin|Chromatin Assembly and Disassembly|DNA Helicases|DNA-Binding Proteins|Haploinsufficiency|Phenotype|Heterozygotes|Mutation|Gene Expression|Chd2 protein, mouse 145 chd2 31703148 Chemphyschem 2019 10.1002/cphc.201900959 1 0 0 105 *Proteins|Nuclear Magnetic Resonance, Biomolecular|Nitrogen Isotopes|Carbon Isotopes|Isoleucine|Leucine|Valine|*Magnetic Resonance Imaging|Malate Synthase 145 chd2 31677157 Dev Med Child Neurol 2019 10.1111/dmcn.14367 0 0 0 105 Humans|*Epilepsy|West Syndrome|*Phenotypes|Epilepsies, Myoclonic|Electroencephalography|Seizures|Lennox Gastaut Syndrome|Febrile Seizures|Mutation|Brain|DNA-Binding Proteins|Sequencing, Next-Generation|CHD2 protein, human 145 chd2 31657568 J Phys Chem A 2019 10.1021/acs.jpca.9b09045 0 0 0 105 Spectrophotometry, Infrared 145 chd2 31580078 J Phys Chem B 2019 10.1021/acs.jpcb.9b06408 0 1 0 105 145 chd2 31539115 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201909_18833 3 3 0 105 Humans|Female|*RNA, Circular|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|MicroRNAs|Cell Proliferation|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|MIRN144 microRNA, human 145 CHD6 31222274 J. Anim. Sci. 2019 PMC6488331 10.1093/jas/skz091 1 0 0 261 Humans|Swine|Animals|*mRNA|*miRNA|*Transcriptome|*Transcriptome Analysis|Muscle Development|Regulatory Network, Gene|Breeding|Muscle Fibers, Skeletal|Gene Expression Regulation, Developmental|Sus scrofa|*Biological Phenomena|Muscle, Skeletal|*Epigenesis, Genetic|Embryonic Development|Downregulation|Meat|Phenotype 31 CHD6 30651562 Nat Commun 2019 PMC6335469 10.1038/s41467-018-08111-y 2 2 0 261 *Chromatin Assembly and Disassembly|Nucleosome|ADP Ribose, Poly|DNA Damage|DNA Repair|DNA Helicases|Chromatin|Poly (ADP-Ribose) Polymerase-1|DNA-Binding Proteins|Poly(ADP-ribose) Polymerases|DNA Breaks|Oxidative Stress 31 CHD6 30598658 Clin Proteomics 2019 PMC6302491 10.1186/s12014-018-9215-z 0 0 0 261 Humans|Female|Liquid Chromatography|*Carcinoma, Ovarian Epithelial|*Peptides|Spectrometry, Mass, Electrospray Ionization|Tandem Mass Spectrometry|Proteomics|Proteins|*Ovarian Cancer|*Plasma|Algorithms 31 CHI3L2 31810965 Anticancer Res. 2019 10.21873/anticanres.13915 0 0 0 30 *Carcinoma, Renal Cell|Neoplasm Recurrence, Local|Kidney Neoplasms|Nephrectomy|*Disease Progression|Prognosis|Biomarkers, Tumor|Kaplan-Meier Estimate|Gene Expression Regulation, Neoplastic|*Macrophages|Chitinases 35 CHI3L2 31123140 J. Neurol. Neurosurg. Psychiatry 2019 10.1136/jnnp-2019-320442 5 0 0 30 *Amyotrophic Lateral Sclerosis|*Chitinase|chitotriosidase|Hexosaminidases|TYRP1 protein, human|*Membrane Glycoproteins|Disease Progression|Case-Control Studies|Biomarkers 35 CHI3L2 30942874 JAMA Surg 2019 PMC6583393 10.1001/jamasurg.2019.0484 4 0 0 30 Humans|Early Detection of Cancer|Pancreatic Carcinoma|*Pancreatic Neoplasms|Carcinoma, Pancreatic Ductal|Pancreatectomy|Prognosis|Adenocarcinoma|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 35 CHI3L2 30797944 Osteoarthr. Cartil. 2019 PMC6536326 10.1016/j.joca.2019.02.792 2 0 0 30 *Cartilage, Articular|Menisci, Tibial|Tibial Meniscus Injuries|Osteoarthritis, Knee|Knee Joint|Arthroscopy|Transcriptome|Gene Expression Profiling|*Phenotype 35 CHRFAM7A 31707211 Stem Cell Res 2019 10.1016/j.scr.2019.101642 0 3 0 87 Animals|Humans|*alpha7 Nicotinic Acetylcholine Receptor|*Induced Pluripotent Stem Cells|*Neurons|*Synaptic Transmission|Nicotinic Acetylcholine Receptor|Patch-Clamp Techniques|1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea|Isoxazoles|Acetylcholine|Phenylurea Compounds|PNU-282987|Bridged Bicyclo Compounds|*Neural Networks, Computer|Allosteric Regulation|JNJ-39393406|Pyridines|Benzamides|Triazoles 57 CHRFAM7A 31583530 Aging Clin Exp Res 2019 10.1007/s40520-019-01359-4 0 4 0 87 *Cholinesterase Inhibitors|*Neuroimmunomodulation|Alzheimer Disease|alpha7 Nicotinic Acetylcholine Receptor|Amyloid beta-Peptides|Nicotinic Acetylcholine Receptor|Cognition Disorders|Synapses 57 CHRFAM7A 31348980 Gene 2019 10.1016/j.gene.2019.143996 0 0 0 87 Animals|Mice|Humans|*Transgenic Mouse|*Proteomics|Chromatography, Liquid|Tandem Mass Spectrometry|*Brain|alpha7 Nicotinic Acetylcholine Receptor|Protein Binding|*Gene Expression Profiling|Genes, Duplicate 57 CHRFAM7A 31048268 J. Neuroimmunol. 2019 10.1016/j.jneuroim.2019.04.012 0 2 0 87 Humans|*Donepezil|*Lipopolysaccharides|*Neuroimmunomodulation|*Macrophages|alpha7 Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptor|Inflammation|Chrna7 protein, human 57 CHRFAM7A 30944217 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6475388 10.1073/pnas.1821853116 1 0 0 87 Animals|Mice|Humans|Neurodegenerative Diseases|*Hematopoietic Stem Cell|alpha7 Nicotinic Acetylcholine Receptor|Mice, Transgenic|Inflammation|Disease Models, Animal|Cognitive Function 57 CHRFAM7A 30924722 J. Neurotrauma 2019 10.1089/neu.2018.6200 1 0 0 87 alpha7 Nicotinic Acetylcholine Receptor|*Genetic Polymorphisms|Cytokines|Gene, Duplicate|Synaptic Transmission 57 CHRFAM7A 30710073 Transl Psychiatry 2019 PMC6358606 10.1038/s41398-019-0375-z 2 0 0 87 Animals|Humans|*Nicotinic Acetylcholine Receptor|Amyloid beta-Peptides|DNA Copy Number Variations|alpha7 Nicotinic Acetylcholine Receptor|*Induced Pluripotent Stem Cells|Synaptic Transmission|Cognition 57 CISD1 31779701 Hum. Genomics 2019 PMC6883692 10.1186/s40246-019-0247-x 0 1 0 191 Humans|Male|*Interferon|*Monocytes|*Transcriptome|*Depression|Cohort Studies|*HIV Infections|*Smoking, Tobacco|*Transcriptome Analysis|*Antiviral Agents|Smoking 84 CISD1 31527235 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6778226 10.1073/pnas.1908271116 1 0 0 191 Humans|CISD1 protein, human|*Mitochondrial Proteins|VDAC1 protein, human|Voltage-Dependent Anion Channel 1|*Redox|Mitochondrial Membrane, Outer|*VDAC Proteins|Mitochondria|Iron-Sulfur Proteins|Reactive Oxygen Species|Pioglitazone|Thiazolidinediones|Iron 84 CISD1 31117349 Chem. Res. Toxicol. 2019 10.1021/acs.chemrestox.9b00166 1 1 0 191 4-hydroxy-2-nonenal|Proteomics|CISD1 protein, human|*Mitochondrial Proteins|Aldehydes|Mitochondrial Membranes|Iron-Sulfur Proteins|Mitochondria|Oxidation-Reduction|Thiazolidinediones|Iron 84 CISD1 31050203 Dev Neurobiol 2019 PMC6543812 10.1002/dneu.22684 1 1 0 191 Animals|Mice|*Proteomics|CISD1 protein, human|*Mitochondrial Proteins|*Mitochondria|Membrane Potential, Mitochondrial|Iron-Binding Proteins|Synapses|*Brain|Membrane Proteins|Proteome|Energy Metabolism|*Neurons|mitoNEET protein, mouse 84 CISD1 31010844 J. Pharmacol. Exp. Ther. 2019 PMC6538890 10.1124/jpet.118.255984 0 1 0 191 Cytarabine|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Burkitt Lymphoma|Drug Resistance, Neoplasm|Antimetabolites, Antineoplastic|Cell Line, Tumor|Vincristine|CISD1 protein, human|*Mitochondrial Proteins|Apoptosis|Methotrexate|B-Lymphocytes 84 CISD1 30805086 Oxid Med Cell Longev 2019 PMC6360568 10.1155/2019/9817576 4 36 0 191 Humans|*Reactive Oxygen Species|isoliquiritigenin|*Melanoma|*Apoptosis|*Chalcones|Membrane Potential, Mitochondrial|Mitochondria|CISD1 protein, human|*Protein, Mitochondrial|Cell Proliferation|Cell Line, Tumor|Signal Transduction 84 CISD1 30770154 Bioorg. Med. Chem. Lett. 2019 PMC6542280 10.1016/j.bmcl.2019.01.041 0 2 0 191 *Thiazolidinediones|CISD1 protein, human|Mitochondrial Proteins|*Endoplasmic Reticulum|Iron-Sulfur Proteins|Mitochondria|Protein Binding|Pioglitazone|Ligands|Redox|Homeostasis|Autophagy|Nutrients 84 CISD1 32382661 Commun Chem 2019 PMC7205193 10.1038/s42004-019-0172-x 0 0 0 191 CISD1 protein, human|*Protein, Mitochondrial|Iron-Sulfur Proteins|Mitochondrial Membranes|*Ligands|Thiazolidinediones|Pioglitazone 84 CIZ1 31252164 Gene 2019 10.1016/j.gene.2019.143946 2 2 0 143 *Urinary Bladder Neoplasms|*Bladder|*Cell Cycle Proteins|Cell Proliferation|Apoptosis|CCND1 protein, human|Cyclin D1|Cell Line, Tumor|CASP3 protein, human|Caspase 3|Gene Knockdown Techniques|Gene Expression Regulation, Neoplastic|Carcinogenesis|Nuclear Proteins|Signal Transduction|RNA, Small Interfering|Cell Division|*Cell Death 70 CIZ1 30956059 Parkinsonism Relat. Disord. 2019 PMC6739171 10.1016/j.parkreldis.2019.04.003 2 0 0 143 Humans|*Blepharospasm|Dystonia, Focal|Meige Syndrome|*Genetic Screening|Ciz1 protein, human|Nuclear Proteins 70 CIZ1 30692537 Nat Commun 2019 PMC6484225 10.1038/s41467-018-08072-2 1 1 0 143 Mice|Animals|Chromatin|Polycomb Repressive Complex 2|Polycomb-Group Proteins|*Cell Differentiation|Histones|Enhancer of Zeste Homolog 2 Protein|*Fibroblasts|Methylation|Polycomb Repressive Complex 1|S Phase|*Epigenetic|Cells, Cultured|Epigenesis, Genetic|Ciz1 protein, mouse|Nuclear Proteins 70 CLEC11A 31494095 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111613 0 0 0 80 Humans|Mice|Animals|*Lipid Metabolism|Islet Cells|Insulin-Secreting Cells|Diet, High-Fat|Insulin|Obesity|Mice, Obese|Signal Transduction|Disease Models, Animal|Cell Proliferation|CLEC11A protein, human|Hematopoietic Cell Growth Factors|Lectins, C-Type 32 CLEC11A 31323382 Clin. Gastroenterol. Hepatol. 2019 PMC6984349 10.1016/j.cgh.2019.07.017 1 0 0 80 Humans|*Pancreatic Juice|*B-DNA|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Carcinoma, Papillary|Methylations, DNA|Pancreas|Biomarkers, Tumor 32 CLEC11A 31265461 PLoS Biol. 2019 PMC6629148 10.1371/journal.pbio.3000350 0 2 0 80 Mice|Animals|*Haploidy|*Embryonic Stem Cells|Guide RNA|CRISPR-Cas Systems|Gene Editing|*Genetic Screening|CRISPR|Mouse Embryonic Stem Cells|Gene Library|*Bone Development 32 CLEC11A 31023895 Science 2019 PMC6816238 10.1126/science.aav2501 32 0 0 80 Humans|Mice|Animals|*Mesenchymal Stem Cells|*Adipose Tissue|Adipocyte|Adipogenesis|Cell Differentiation|Progenitor Cells|DPP4 protein, human|Dipeptidyl-Peptidase IV|Adipose Tissue, Subcutaneous|Cells, Cultured 32 CLEC11A 30786351 Zhonghua Yi Xue Za Zhi 2019 10.3760/cma.j.issn.0376-2491.2019.07.010 0 0 0 80 32 CLEC11A 30632962 Elife 2019 PMC6349404 10.7554/eLife.42274 3 19 0 80 Humans|Adult|Osteogenesis|*Bone and Bones|Osteoblasts|*Integrins|Mesenchymal Stem Cells|Cell Differentiation|leptin receptor, human|Receptor, Leptin|*Bone Density|Cells, Cultured 32 CLIC1 31879279 Life Sci Alliance 2019 PMC6933522 10.26508/lsa.201900558 3 0 0 322 Animals|*Actins|*Cytokinesis|actin-binding protein anillin, human|Microfilament Proteins|ezrin|Cytoskeletal Proteins|CLIC4 protein, human|*Channel, Chloride|*Plasma Membrane|RHOA protein, human|rhoA GTP-Binding Protein|anillin|Contractile Proteins|Actin Cytoskeleton|Cell Division|Spindle Apparatus|Protein Transport|Cytoplasm 202 CLIC1 31834994 Cell. Physiol. Biochem. 2019 10.33594/000000193 0 0 0 322 Potassium Channels|Pancreatic Carcinoma|*Pancreas Cancer|Calcium Channels|Carcinoma, Pancreatic Ductal|Chloride Channels|*Cytoplasm|Gastrointestinal Neoplasms|Ions|Carcinogenesis|Tumor Microenvironment 202 CLIC1 31803233 Front Genet 2019 PMC6872675 10.3389/fgene.2019.01143 1 0 0 322 *Tumor Microenvironment|*Prognosis|*Glioma|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Kaplan-Meier Estimate|Gene Modules 202 CLIC1 31791876 Biosens Bioelectron 2019 10.1016/j.bios.2019.111920 0 0 0 322 Humans|*Microfluidics|Lipid Bilayers|Ion Channel|Channel, Chloride Ion|*Chlorides|*Cytoplasm|Electrophysiological Phenomena|Water 202 CLIC1 31652719 Antioxidants (Basel) 2019 PMC6912460 10.3390/antiox8110505 0 1 0 322 Humans|*Peroxiredoxin VI|*Hep G2 Cells|*Down-Regulation|Proteomics|Redox|Peroxiredoxins|Oxidative Stress|Phospholipases A2|*Cell Cycle Arrest|Antioxidants|Hydroperoxide|*Biochemical Phenomena|Phospholipids|CLIC1 protein, human|Chloride Channels 202 CLIC1 31636470 World J. Gastroenterol. 2019 PMC6801186 10.3748/wjg.v25.i38.5732 3 4 0 322 *Gastrointestinal Cancer|Oncogenesis|Ion Channels 202 CLIC1 31572530 Exp Ther Med 2019 PMC6755458 10.3892/etm.2019.7888 0 0 0 322 Humans|*Parkinson Disease|*Proteomics|*Computational Biology|Hedgehog Proteins|Deep Brain Stimulation|*Biomarkers|Chromatography, Liquid|*Plasma|CLIC1 protein, human|Chloride Channels 202 CLIC1 31483794 PLoS Negl Trop Dis 2019 PMC6746389 10.1371/journal.pntd.0007703 0 1 0 322 Humans|Chlorocebus aethiops|Animals|*Chikungunya virus|*Chikungunya Fever|Virus Replication|Viral Nonstructural Proteins|Replicon|Aedes|RNA, Viral|Vero Cells|Antiviral Agents|Cell Line|Chloride Channels|CLIC4 protein, human|CLIC1 protein, human 202 CLIC1 31473882 Mol. Cell. Biochem. 2019 10.1007/s11010-019-03613-9 2 0 0 322 *Vincristine|*Stomach Neoplasms|*Exosomes|Drug Resistance, Multiple|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Line, Tumor|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|ATP Binding Cassette Transporter, Subfamily B, Member 1|Stomach|RNA Interference|Cell Proliferation|Apoptosis|CLIC1 protein, rat|Chloride Channels|Up-Regulation 202 CLIC1 31398428 Prog. Neuropsychopharmacol. Biol. Psychiatry 2019 10.1016/j.pnpbp.2019.109729 0 0 0 322 *Genome-Wide Association Study|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Pedigree|Brain 202 CLIC1 31364737 Oncol. Rep. 2019 PMC6718097 10.3892/or.2019.7250 1 7 0 322 Humans|Liver Cancer|Carcinoma, Hepatocellular|MIRN124 microRNA, human|MicroRNAs|Cell Migration|Cell Proliferation|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Downregulation|mRNA|Hep G2 Cells|Cell Line, Tumor|Apoptosis|Chloride Channels|*Cytoplasm|*Chlorides|CLIC1 protein, human 202 CLIC4 31879279 Life Sci Alliance 2019 PMC6933522 10.26508/lsa.201900558 3 0 0 385 Animals|*Actins|*Cytokinesis|actin-binding protein anillin, human|Microfilament Proteins|ezrin|Cytoskeletal Proteins|CLIC4 protein, human|*Channel, Chloride|*Plasma Membrane|RHOA protein, human|rhoA GTP-Binding Protein|anillin|Contractile Proteins|Actin Cytoskeleton|Cell Division|Spindle Apparatus|Protein Transport|Cytoplasm 122 CLIC4 31744714 Nutr Metab Cardiovasc Dis 2019 10.1016/j.numecd.2019.09.027 1 1 0 385 oxidized low density lipoprotein|*Lipoproteins, LDL|*Apoptosis|MicroRNAs|Atherosclerosis|Endothelial Cells|Cell Proliferation|Signal Transduction|CLIC4 protein, human|*Chloride Channels|Aorta 122 CLIC4 31693917 Toxicology 2019 10.1016/j.tox.2019.152312 0 5 0 385 Rats|Animals|lipopolysaccharide B|*Lipopolysaccharides|*Neurodegenerative Diseases|CLIC4 protein, human|*Channel, Chloride|Apoptosis|Mitochondrial Proteins|CASP3 protein, human|Caspase 3|Mitochondria|Apoptosis Regulatory Proteins|Cell Death|Cell Line, Tumor|Cytochromes c|Clic4 protein, rat 122 CLIC4 31633381 Cell Reprogram 2019 10.1089/cell.2019.0056 0 0 0 385 Dogs|Animals|*Nuclear Transfer Techniques|Cloning|*Transcriptome Analysis|Preimplantation Embryos|mRNA|Reproduction|miRNA 122 CLIC4 31560739 Carcinogenesis 2019 10.1093/carcin/bgz156 1 2 0 385 Mice|Animals|*Epithelial-Mesenchymal Transition|*Stomach Neoplasms|Mice, Nude|CLIC4 protein, human|*Chloride Channels|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|CD44 protein, human|Hyaluronan Receptors|Cell Proliferation|5 Fluorouracil|Tumorigenesis|Downregulation 122 CLIC4 31483794 PLoS Negl Trop Dis 2019 PMC6746389 10.1371/journal.pntd.0007703 0 1 0 385 Humans|Chlorocebus aethiops|Animals|*Chikungunya virus|*Chikungunya Fever|Virus Replication|Viral Nonstructural Proteins|Replicon|Aedes|RNA, Viral|Vero Cells|Antiviral Agents|Cell Line|Chloride Channels|CLIC4 protein, human|CLIC1 protein, human 122 CLIC4 31439888 Sci Rep 2019 PMC6706427 10.1038/s41598-019-48438-0 0 2 0 385 Humans|MMP14 protein, human|*Matrix Metalloproteinase 14|*Focal Adhesions|*Protein Transport|*Cell Movement|*Endosomes|CLIC4 protein, human|*Chloride Channels|Cell Adhesion|Tsg101 protein|DNA-Binding Proteins|Endosomal Sorting Complexes Required for Transport|Transcription Factors|Extracellular Matrix|Proteolysis|Matrix Metalloproteinase 2 122 CLIC4 30907395 Food Funct 2019 10.1039/c8fo01756e 0 2 0 385 Mice|Animals|*Irinotecan|dihydromyricetin|*Colon Cancer|*Flavonols|Colorectal Cancer|*Disease Models, Animal|Colitis|Colon|CLIC4 protein, human|Chloride Channels|*Disease Progression 122 CLIC6 31757997 Sci Rep 2019 PMC6874604 10.1038/s41598-019-53654-9 0 0 0 37 Humans|Female|*Genome-Wide Association Study|Japan|Linkage Disequilibrium|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Case-Control Studies 21 CLMN 31776323 Med. Sci. Monit. 2019 PMC6900925 10.12659/MSM.917925 0 0 0 48 *mRNA|Gene Ontology|*Myocardial Infarction|Gene Regulatory Networks|Gene Expression Profiling|MicroRNAs|Transcriptome|Myocardium|Bioinformatics|Real-Time PCR, Quantitative|Signal Transduction Pathways 29 CLMN 31377468 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109234 0 0 0 48 Mice|Animals|*Myocardial Infarction|Myocardium|Ventricular Remodeling|Traditional Chinese Medicine|Myocytes, Cardiac|Cardiotonic Agents|Fibrosis|Drugs, Chinese Herbal|Apoptosis|Disease Models, Animal|Signal Transduction 29 CLMP 31783056 J. Allergy Clin. Immunol. 2019 10.1016/j.jaci.2019.11.023 0 1 0 63 4-phenylenediamine|*Phenylenediamines|Hair Dyes|Allergic Contact Dermatitis|Patch Tests|Dermatitis, Occupational|Occupational Exposure 584 CLMP 31465819 Toxicology 2019 10.1016/j.tox.2019.152282 0 3 0 63 Male|Female|Humans|Rats|Animals|metazachlor|*Rats, Sprague-Dawley|*Rats, Wistar|Hepatocytes|Phenobarbital|constitutive androstane receptor|Receptors, Cytoplasmic and Nuclear|Liver|*Acetamides|Liver Neoplasms|Cytochrome P450|Liver Neoplasms, Experimental|Cytochrome P-450 CYP2B6|Replications, DNA|Pyrethrins|Organ Size|Cells, Cultured|Cytochrome 584 CLMP 31373105 Mol. Reprod. Dev. 2019 10.1002/mrd.23250 1 1 0 63 Mice|Animals|*Tight Junctions|*Trophoblasts|adenovirus receptor|*Adenovirus|TJP1 protein, human|Tight Junction Protein 1|Blastocyst|*Receptors, Virus|Embryonic Development|*ADAM10 Protein|Occludin|*Cell Membrane|Coxsackie and Adenovirus Receptor-Like Membrane Protein|*Coxsackievirus Infections|*Adenoviridae Infections|Gene Expression Regulation, Developmental|Embryo, Mammalian|Embryo Implantation 584 CLMP 31296182 BMC Cancer 2019 PMC6624952 10.1186/s12885-019-5842-7 1 0 0 63 Humans|*Microsatellite Instability|*Proto-Oncogene Proteins B-raf|*Proto-Oncogene Proteins p21(ras)|*Colorectal Cancer|ras Proteins|*Colonic Neoplasms|CpG Islands|Proto-Oncogene Proteins|DNA Methylation|Mutation|TNM Staging System|Biomarkers, Tumor|Kaplan-Meier Estimate|Phenotype|Disease-Free Survival|Proportional Hazards Models|Cohort Studies|KRAS protein, human 584 CLMP 31163079 PLoS Pathog. 2019 PMC6548406 10.1371/journal.ppat.1007817 7 0 0 63 Mice|Animals|*Schistosoma japonicum|*miRNA|Schistosomiasis japonica|*Extracellular Vesicle|*Macrophage 584 CLMP 31083261 Medicine (Baltimore) 2019 PMC6531060 10.1097/MD.0000000000015629 0 0 0 63 Humans|adenovirus receptor|*Coxsackievirus Infection|*Receptors, Virus|Enterovirus B, Human|*Enterovirus|Coxsackie Adenovirus Receptor|Myocarditis|Virus Replication|HeLa Cells|*Heart Injuries 584 CLMP 31061750 J Pediatr Genet 2019 PMC6499612 10.1055/s-0038-1675339 0 0 0 63 Humans|Iran|*Congenital Short Bowel Syndrome|*Mutation|Coxsackie and Adenovirus Receptor-Like Membrane Protein|Pedigree|Intestines 584 CLN8 31741823 JIMD Rep 2019 PMC6850977 10.1002/jmd2.12057 0 0 0 146 *Neuronal Ceroid-Lipofuscinoses|Membrane Proteins|Mutation 130 CLN8 31689978 Int J Mol Sci 2019 PMC6862079 10.3390/ijms20215484 0 0 0 146 Maize|Gene Duplication|Phylogeny|Gene Expression Regulation, Plant|Evolution, Molecular|Genes, Plant|Multigene Family|Genome, Plant|Plant Proteins|Segmental Duplication, Genomic|Amino Acid Sequence|Gene Expression Profiling 130 CLN8 31687336 Mol Genet Metab Rep 2019 PMC6819867 10.1016/j.ymgmr.2019.100521 0 0 0 146 Male|Dogs|Animals|Female|*Neuronal Ceroid-Lipofuscinoses|Homozygote|Pedigree|Dog Diseases|Breeding|Cerebellum|Membrane Proteins|Alleles 130 CLN8 31462087 Connect. Tissue Res. 2019 PMC7047581 10.1080/03008207.2019.1657425 1 0 0 146 130 CLN8 31105743 Front Genet 2019 PMC6494930 10.3389/fgene.2019.00370 0 0 0 146 Humans|*Neuronal Ceroid-Lipofuscinoses|*Siblings|*Sequencing, Next-Generation|*Chinese|Mutations|MFSD8 protein, human|Membrane Transport Proteins|Pedigree|Membrane Proteins|Phenotypes|Seizures|Brain 130 CLN8 31029456 Brain Dev. 2019 10.1016/j.braindev.2019.04.009 0 0 0 146 Humans|Male|Child, Preschool|*Walking|Ceroid Lipofuscinosis, Neuronal, 10|Neuronal Ceroid Lipofuscinoses|*Mutation|Membrane Proteins|Epilepsy|Cathepsin D|CLN6 protein, human 130 CLN8 30919163 Neuromolecular Med. 2019 10.1007/s12017-019-08529-7 1 0 0 146 Child|Humans|Male|Child, Preschool|*Neuronal Ceroid-Lipofuscinoses|Iran|Mutations|Pedigree|Membrane Proteins|Homozygotes|Exon|*Lysosomes|CLN5 protein, human|CLN8 protein, human 130 CLN8 30741402 Rev Neurol 2019 0 0 0 146 Humans|Child|*Neuronal Ceroid-Lipofuscinoses|*Phenotype|Pedigree|Membrane Proteins|Mutation|Epilepsy|Turkey|Finland|CLN8 protein, human 130 CLPB 31847479 Int J Mol Sci 2019 PMC6941012 10.3390/ijms20246325 0 0 0 384 Leptospira interrogans|Gene Expression Regulation, Bacterial|Bacterial Proteins|Spirochete 563 CLPB 31810333 Biomolecules 2019 PMC6995612 10.3390/biom9120815 0 0 0 384 HSP70 Heat-Shock Proteins|Endopeptidase Clp|Heat-Shock Proteins|Escherichia coli Proteins|Molecular Chaperones|Bacterial Proteins|Protein Binding|Protein Unfolding|Stress, Heat|Hot Temperature 563 CLPB 31786767 Mol. Biol. Rep. 2019 10.1007/s11033-019-05209-4 0 1 0 384 *Acinetobacter baumannii|*Up-Regulation|*Monobactams|Sulbactam|Acinetobacter Infections|Antibiotic|Ampicillin|Thienamycins|beta-Lactams|Meropenem|*Heat Shock|Microbial Sensitivity Tests 563 CLPTM1L 31626034 Melanoma Res. 2019 10.1097/CMR.0000000000000641 0 0 0 70 Humans|Uveal melanoma|Melanoma, Cutaneous Malignant|*Melanoma|*Genome-Wide Association Study|Skin Neoplasms|*Uveal Neoplasms|Ubiquitin Thiolesterase|Germ-Line Mutation|Tumor Suppressor Proteins|Genetic Predisposition to Disease|Eye Color|Mutations|Skin Color|Chromosomal Aberrations|DNA Repair|BAP1 protein, human|TDP1 protein, human|Phosphoric Diester Hydrolases 151 CLPTM1L 31474360 Trends Cancer 2019 PMC6777873 10.1016/j.trecan.2019.07.005 0 1 0 70 Humans|Child|*Transcription Factors|*Zinc Finger|GLI1 protein, human|*Zinc Finger Protein GLI1|CBFA2T3 protein, human|Repressor Proteins|Kruppel-Like Transcription Factors|Tumor Suppressor Proteins|*Leukemia|*Cancers|Signal Transduction|Leukemia, Megakaryoblastic, Acute|Epithelial-Mesenchymal Transition|Cell Differentiation 151 CLPTM1L 31429604 DNA Cell Biol. 2019 10.1089/dna.2019.4744 0 0 0 70 Humans|Transcriptase, Telomerase Reverse|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Neoplasm Proteins|Genetic Association Studies|Asian Continental Ancestry Group|Membrane Proteins|Carcinoma, Squamous Cell|Case-Control Studies|Genotype|Lung Neoplasms|Risk Factors 151 CLPTM1L 31289279 Sci Rep 2019 PMC6617453 10.1038/s41598-019-46137-4 1 0 0 70 Humans|*Nasopharyngeal Carcinoma|*Whole Exome Sequencing|Epstein Barr Virus Infection|Nasopharyngeal Neoplasms|Herpesvirus 4, Human|Carcinoma|Genetic Susceptibility|Genome, Viral|Antibodies, Viral|Exome|Case-Control Studies|Carcinogenesis|Taiwan|RAPGEF3 protein, human|Guanine Nucleotide Exchange Factors|BCL2L12 protein, human|Muscle Proteins|Proto-Oncogene Proteins c-bcl-2 151 CLPTM1L 31270100 Cancer Epidemiol. Biomarkers Prev. 2019 PMC6774819 10.1158/1055-9965.EPI-19-0007 0 0 0 70 Humans|*Nasopharyngeal Carcinoma|Genetic Susceptibility|Nasopharyngeal Neoplasms|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Carcinoma|Haplotypes|Asian Continental Ancestry Group|Genotype|Neoplasm Proteins|Case-Control Studies|Telomerase|Membrane Proteins|Risk Factors 151 CLPTM1L 31203567 Fam. Cancer 2019 PMC6784815 10.1007/s10689-019-00137-5 0 0 0 70 Humans|Genome-Wide Association Study|Melanoma, Cutaneous Malignant|*Melanoma|*Pancreatic Cancer|Skin Neoplasms|Genes, p16|*Modifier Gene|Cyclin-Dependent Kinase Inhibitor p16|Allele|Mutation|Genetic Predisposition to Disease|Heterozygote|*Risk|Exon|Cohort Studies|Netherlands|TERT protein, human|Telomerase 151 CLPTM1L 31009812 J Thorac Oncol 2019 PMC6833942 10.1016/j.jtho.2019.04.008 1 0 0 70 Humans|Genome-Wide Association Study|*Smokers|*Lung Cancer|Genetic Predisposition to Disease|Carcinoma, Non-Small-Cell Lung|Asians|Polymorphism, Single Nucleotide|Adenocarcinoma|Linkage Disequilibrium|Case-Control Studies|Carcinoma, Squamous Cell|Neoplasm Proteins|Telomerase|Genotype|Smoking|Membrane Proteins|Risk Factors|*DNA Mutational Analysis 151 CLPTM1L 30635792 J. Cancer Res. Clin. Oncol. 2019 10.1007/s00432-019-02843-0 1 1 0 70 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*Cleft Palate|Squamous Cell Carcinoma of Head and Neck|Prognosis|Cell Line, Tumor|Biomarkers, Tumor|TRAPPC10 protein, human|*Vesicular Transport Proteins|Cell Proliferation|Cell Movement|Cisplatin|Head and Neck Neoplasms|CLPTM1 protein, human|Membrane Proteins 151 CLSTN2 31529526 Synapse 2019 10.1002/syn.22132 0 0 0 215 Animals|Mice|calsyntenin-2, mouse|Calcium-Binding Proteins|Synapses|Membrane Proteins|Synaptic Vesicles|Hippocampus|Interneurons|Neurons|Mice, Knockout|Memory, Spatial|Social Behavior 32 CMPK2 31125665 Fish Shellfish Immunol. 2019 10.1016/j.fsi.2019.05.032 2 2 0 29 Animals|Carp sprivivirus|*Interferon|*Rhabdoviridae|Rhabdoviridae Infections|Reoviridae Infections|Carps|Fish Diseases|Reoviridae|Fish Proteins|Zebrafish|Immunity, Innate|Zebrafish Proteins|*Antiviral Agents|Poly I-C|Sequence Alignment|Amino Acid Sequence|Gene Expression Profiling|Phylogeny 21 CMPK2 30870785 Domest. Anim. Endocrinol. 2019 10.1016/j.domaniend.2019.01.006 0 0 0 29 Pregnancy|Cattle|Female|Animals|trophoblastin|uridine monophosphate kinase|Pregnancy Proteins|Interferon Type I|Inseminations, Artificial|*Granulocytes|Pregnancy, Animal|Pregnancy Tests|Gene Expression|*Neutrophils|Leukocytes|Gene Expression Regulation|*Leukocyte Count|*Regulatory Sequences, Nucleic Acid|Basic Helix-Loop-Helix Transcription Factors|Cytidine 21 CMPK2 30826544 Ecotoxicol. Environ. Saf. 2019 10.1016/j.ecoenv.2019.01.126 0 0 0 29 Animals|bisphenol A|*Zebrafish|*Larvae|*RNA-Seq|bisphenol B|*Benzhydryl Compounds|bisphenol F|*Phenols|bis(4-hydroxyphenyl)sulfone|Sulfones|Endocrine Disruptors|*Biological Processes 21 CMPK2 30662451 Front Genet 2019 PMC6329279 10.3389/fgene.2018.00682 1 0 0 29 *Cancer|CD274 protein, human|B7-H1 Antigen|*Oncogenes|Immunotherapy|CTLA4 protein, human|CTLA-4 Antigen|Data Mining|Databases, Genetic|*Gene Expression 21 CNDP1 31362685 Curr. Med. Chem. 2019 10.2174/0929867326666190730130024 0 1 0 125 Humans|*Carnosine|Diabetic Nephropathy|Dipeptidases|Kidney|Polymorphism, Genetic|Diabetes Mellitus, Type 2|Genetic Predisposition to Disease|Acute Kidney Injury|Angiotensin-Converting Enzyme Inhibitors|CNDP1 protein, human 70 CNDP1 31073745 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03127-z 1 0 0 125 Animals|*Zebrafish|Diabetic Nephropathy|Carnosine|*Diabetic Complications|Dipeptidases|Kidneys|Diabetes Mellitus, Type 2|*Protective Agents|*Gain, Weight|Amino Acids 70 CNDP1 30914013 Curr. Med. Chem. 2019 10.2174/0929867326666190326111851 2 0 0 125 Humans|*Diabetic Nephropathies|*Carnosine|Diabetes Mellitus, Type 2|Dipeptidases|Kidney|Genetic Predisposition to Disease|Polymorphism, Genetic|End Stage Renal Disease|CNDP1 protein, human 70 CNDP1 30719346 J Nutr Metab 2019 PMC6335667 10.1155/2019/8736215 1 0 0 125 Humans|*Diabetic Nephropathies|Diabetes Mellitus, Type 2|*Risk Factors|Malaysia|aminoacyl-histidine dipeptidase|Dipeptidases|Genetic Predisposition to Disease|superoxide dismutase 2|*Mn-SOD|Polymorphism, Single Nucleotide|Haplotypes|Genotype|Nitric Oxide Synthase Type III|NOS3 protein, human|CNDP1 protein, human 70 CNDP1 30610469 Amino Acids 2019 10.1007/s00726-018-02692-0 1 0 0 125 Humans|aminoacyl-histidine dipeptidase|*Diabetes Mellitus, Type 2|Cross-Sectional Studies|*Dipeptidases|Diabetic Nephropathy|*Genotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|CNDP1 protein, human 70 CNDP1 30605725 J Proteomics 2019 10.1016/j.jprot.2018.12.031 2 0 0 125 Humans|*Polycythemia|*Proteome|*Altitude|*Proteomics|*Altitude Sickness|*Gene Expression Profiling|Polymorphism, Single Nucleotide|Case-Control Studies|Biomarkers|*Plasma|Bioinformatics|MASP1 protein, human|Mannose-Binding Protein-Associated Serine Proteases|CNDP1 protein, human|Dipeptidases 70 cnga3 31877759 Genes (Basel) 2019 PMC7017091 10.3390/genes11010012 0 0 0 111 Pakistan|*Retinal Diseases|Pedigree|DNA Mutational Analysis|Exome|Homozygote|Leber Congenital Amaurosis|Single Nucleotide Polymorphism|Sequencing, Whole Exome|Genetic Predisposition to Disease|Phenotype|Mutation 221 cnga3 31846668 Curr. Biol. 2019 PMC6926481 10.1016/j.cub.2019.10.028 2 0 0 111 Humans|Mice|Animals|*Color|*Retinal Cone Photoreceptor Cells|melanopsin|Rod Opsins|Perceptions, Color|Photic Stimulation|Circadian Rhythm 221 cnga3 31725702 Retina (Philadelphia, Pa.) 2019 10.1097/IAE.0000000000002675 0 0 0 111 Child|Humans|United Arab Emirates|*Genetic Testing|*Phenotype|Retinal Dystrophies|*Retina|DNA Mutational Analysis|Pedigree|Mutation|Eye Proteins 221 cnga3 31602346 Transl Vis Sci Technol 2019 PMC6779097 10.1167/tvst.8.5.21 0 0 0 111 Achromatopsia 1|*Color Vision Defects|*Retina|Fovea Centralis|Tomography, Optical Coherence|Visual Acuity 221 cnga3 31456290 Hum. Mutat. 2019 10.1002/humu.23903 2 0 0 111 Humans|Israel|*Genetic Screening|Retinitis Pigmentosa|*Retina|Retinal Dystrophies|DNA Mutational Analysis|Mutations|Eye Proteins|Pedigree|Phenotype|ATP-Binding Cassette Transporters|FAM161A protein, human 221 cnga3 31290651 ACS Chem Neurosci 2019 10.1021/acschemneuro.9b00231 0 0 0 111 Gated Channel, Cyclic-Nucleotide|Photoreceptor, Cone|Color Vision Defects|Amino Acid Sequence|Patch-Clamp Techniques|Cyclic GMP|Mutation 221 cnga3 31237654 Invest. Ophthalmol. Vis. Sci. 2019 PMC6594318 10.1167/iovs.19-27047 2 0 0 111 Achromatopsia 1|*Color Vision Defects|*Retina|Electroretinography|Retinal Cone Photoreceptor Cells|Cyclic Nucleotide-Gated Cation Channels|Ophthalmoscopy|Visual Acuity|Tomography, Optical Coherence|Mutations|Phenotype 221 cnga3 31182474 eNeuro 2019 PMC6597858 10.1523/ENEURO.0119-19.2019 1 30 0 111 Animals|Mice|*Gated Channel, Cyclic-Nucleotide|*Ryanodine Receptor Calcium Release Channel|Photoreceptor, Cone|Achromatopsia 1|Achromatopsia|Endoplasmic Reticulum Stress|*Protein Transport|Eye Proteins|Phototransduction|Mice, Knockout|Apoptosis|Nucleotides, Cyclic 221 cnga3 30864850 Hum Gene Ther Clin Dev 2019 10.1089/humc.2018.188 2 0 0 111 Animals|*Gene Therapy|Dependovirus|Color Vision Defects|*Vision, Ocular|Genetic Vectors|Cyclic Nucleotide-Gated Cation Channels|Retinal Cone Photoreceptor Cells|Injections, Intraocular|Electroretinography|Retina|Disease Models, Animal|Primates 221 cnga3 30804581 J Pak Med Assoc 2019 0 0 0 111 Humans|Achromatopsia 1|*Color Vision Defects|*Whole Exome Sequencing|Pakistan|Cyclic Nucleotide-Gated Cation Channels|DNA Mutational Analysis|Retinal Cone Photoreceptor Cells|Pedigree|Electroretinography|Mutation|Mutation, Missense|Amino Acid Sequence|Asian Continental Ancestry Group|Phenotype|Genotype 221 cnga3 30779484 Harefuah 2019 0 0 0 111 Humans|Quality of Life|Retinitis Pigmentosa|*Retina|DNA Mutational Analysis|Electroretinography|*Chromosome Mapping|Genes, Recessive|Pedigree|Eye Proteins|*Retinal Diseases|Mutation 221 cnga3 30711023 Prog Mol Biol Transl Sci 2019 10.1016/bs.pmbts.2018.10.002 0 0 0 111 Humans|Child|Infant|Achromatopsia 1|Achromatopsia|*Mutations|*Genotype-Phenotype Correlation|Cyclic Nucleotide-Gated Cation Channels|Retinal Cone Photoreceptor Cells|Pedigree|Electroretinography|Retinal Diseases|Mutation, Missense 221 cnga3 30682209 Invest. Ophthalmol. Vis. Sci. 2019 PMC6354941 10.1167/iovs.18-25880 3 0 0 111 Achromatopsia 1|*Color Vision Defects|*Retina|Electroretinography|Fovea Centralis|Retinal Cone Photoreceptor Cells|Ophthalmoscopy|Cyclic Nucleotide-Gated Cation Channels|Visual Acuity|Tomography, Optical Coherence 221 CNGB3 31877759 Genes (Basel) 2019 PMC7017091 10.3390/genes11010012 0 0 0 35 Pakistan|*Retinal Diseases|Pedigree|DNA Mutational Analysis|Exome|Homozygote|Leber Congenital Amaurosis|Single Nucleotide Polymorphism|Sequencing, Whole Exome|Genetic Predisposition to Disease|Phenotype|Mutation 153 CNGB3 31776299 Tohoku J. Exp. Med. 2019 10.1620/tjem.249.213 1 0 0 35 Humans|*miRNA|*Aqueous Humor|Vascular Endothelial Growth Factor A|Exosomes|Gene Expression Regulation, Neoplastic|High-Throughput Nucleotide Sequencing|Bioinformatics|*Myopia|Eastern Asia|MIRN582 microRNA, human|MIRN885 microRNA, human 153 CNGB3 31602346 Transl Vis Sci Technol 2019 PMC6779097 10.1167/tvst.8.5.21 0 0 0 35 Achromatopsia 1|*Color Vision Defects|*Retina|Fovea Centralis|Tomography, Optical Coherence|Visual Acuity 153 CNGB3 31573552 Vestn Oftalmol 2019 10.17116/oftalma201913504110 0 0 0 35 Humans|*Retina|*Retinal Diseases|*Mutation|Electroretinography|Macular Degeneration|*Genetic Association Studies|Phenotype|ATP-Binding Cassette Transporters|Tomography, Optical Coherence|Stargardt Disease|Genotype|ABCA4 protein, human 153 CNGB3 31544997 Hum. Mutat. 2019 10.1002/humu.23920 1 0 0 35 Humans|Achromatopsia 1|*Color Vision Defects|*Introns|Cyclic Nucleotide-Gated Cation Channels|DNA Mutational Analysis|Phenotype|Alleles|Mutation|Genotype|RNA Splicing|Base Sequence|CNGB3 protein, human 153 CNGB3 31290651 ACS Chem Neurosci 2019 10.1021/acschemneuro.9b00231 0 0 0 35 Gated Channel, Cyclic-Nucleotide|Photoreceptor, Cone|Color Vision Defects|Amino Acid Sequence|Patch-Clamp Techniques|Cyclic GMP|Mutation 153 CNGB3 31237654 Invest. Ophthalmol. Vis. Sci. 2019 PMC6594318 10.1167/iovs.19-27047 2 0 0 35 Achromatopsia 1|*Color Vision Defects|*Retina|Electroretinography|Retinal Cone Photoreceptor Cells|Cyclic Nucleotide-Gated Cation Channels|Ophthalmoscopy|Visual Acuity|Tomography, Optical Coherence|Mutations|Phenotype 153 CNGB3 31182474 eNeuro 2019 PMC6597858 10.1523/ENEURO.0119-19.2019 1 30 0 35 Animals|Mice|*Gated Channel, Cyclic-Nucleotide|*Ryanodine Receptor Calcium Release Channel|Photoreceptor, Cone|Achromatopsia 1|Achromatopsia|Endoplasmic Reticulum Stress|*Protein Transport|Eye Proteins|Phototransduction|Mice, Knockout|Apoptosis|Nucleotides, Cyclic 153 CNGB3 30826882 Hum. Genet. 2019 PMC6486401 10.1007/s00439-019-01991-0 0 0 0 35 Humans|*Amish|Pennsylvania|*Genetic Linkage Analysis|*Myopia|Lod Score|Chromosome Mapping|Quantitative Trait Loci|Genotype|Pedigree|Genetic Predisposition to Disease|Haplotypes|*Chromosome Structures|Genome, Human|Microsatellite|European Continental Ancestry Group 153 CNGB3 32397729 Cesk Slov Oftalmol 2019 10.31348/2019/5/5 0 0 0 35 Humans|Achromatopsia 1|*Color Vision Defects|Czech Republic|Cyclic Nucleotide-Gated Cation Channels|Retinal Cone Photoreceptor Cells|Electroretinography|DNA Mutational Analysis|Retina|Mutations|Pedigree|Tomography, Optical Coherence|Visual Acuity 153 CNN3 31798778 World J Gastrointest Oncol 2019 PMC6883188 10.4251/wjgo.v11.i11.971 0 7 0 296 calponin|*Microfilament Proteins|*Calcium-Binding Proteins|*Colon Cancer|*Colon|Cytoskeleton|Colorectal Neoplasms|Cell Movement|Cell Line, Tumor|*Drug Resistance 39 CNN3 31683252 Eur J Radiol 2019 10.1016/j.ejrad.2019.108713 0 0 0 296 *Deep Learning|*Aneurysm, Dissecting|Aortography|Computed Tomography Angiography|Radiographic Image Interpretation, Computer-Assisted|Retrospective Studies 39 CNN3 31326556 Cancer Lett. 2019 10.1016/j.canlet.2019.07.013 0 3 0 296 GTP Phosphohydrolases|Antigens, Neoplasm|Biomarkers, Tumor|Autoantibodies|Membrane Proteins|Autoantigens|Mutation|Cell Line, Tumor 39 CNN3 31254429 Cancer Sci. 2019 PMC6726682 10.1111/cas.14118 5 0 0 296 Humans|Male|Dogs|Animals|*Urinary Bladder Neoplasms|*Organoids|Bladder|Cisplatin|Antineoplastic Agents|Piroxicam|Prostate Cancer|Disease Models, Animal|Viability, Cell 39 CNN3 30911294 Gastroenterol Res Pract 2019 PMC6398029 10.1155/2019/3024970 2 19 0 296 calponin|*Stomach Neoplasms|F-actin-binding proteins|*Microfilament Proteins|*Calcium-Binding Proteins|Actin|Cytoskeleton|Cell Movement|Cell Line, Tumor|Doxorubicin 39 CNPY2 31625681 J. Cell. Mol. Med. 2019 PMC6850922 10.1111/jcmm.14688 2 0 0 91 Animals|Rats|*Endoplasmic Reticulum Stress|*Dexmedetomidine|*Spinal Cord Ischemia|*Reperfusion Injury|*Spinal Cord|*Signal Transduction|Caspase 12|CASP3 protein, human|Caspase 3|Neuroprotective Effect|Apoptosis|*Neurons|Neuroprotection 27 CNPY2 31396081 Front Pharmacol 2019 PMC6664686 10.3389/fphar.2019.00789 1 0 0 91 Humans|*Vascular Endothelial Growth Factor A|*Liraglutide|Human Umbilical Vein Endothelial Cells|*Vascular Endothelial Growth Factors|Signal Transduction|Unfolded Protein Response|Cell Hypoxia|Hypoxia|Apoptosis|Neovascularization, Pathologic|Western Blot|CNPY2 protein, human|Adaptor Proteins, Signal Transducing 27 CNPY2 31050855 Protein Sci. 2019 PMC6566547 10.1002/pro.3635 0 0 0 91 Animals|Endoplasmic Reticulum|Protein Folding|Disulfides|Dithiothreitol|Oxidation-Reduction|Biological Transport|LDLR protein, human|Low Density Lipoprotein Receptor|Cysteine 27 CNPY2 31047986 J. Mol. Cell. Cardiol. 2019 10.1016/j.yjmcc.2019.04.018 0 5 0 91 Humans|Animals|Mice|*Mice, Knockout|Cell Proliferation|Cyclin-Dependent Kinase Inhibitor p16|Signal Transduction|CNPY2 protein, human|Adaptor Proteins, Signal Transducing 27 CNPY2 30864682 Int. J. Mol. Med. 2019 PMC6443342 10.3892/ijmm.2019.4123 3 6 0 91 Rats|Animals|*Myocardial Reperfusion Injury|barbaloin|Endoplasmic Reticulum Stress|*Anthracenes|Cardiomyocytes|Cardiotonic Agents|Apoptosis|Myocardium|Transcription Factor CHOP|Signal Transduction|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|Rats, Sprague-Dawley|Heat-Shock Proteins 27 COBLL1 31766143 Nutrients 2019 PMC6893551 10.3390/nu11112751 1 1 0 74 Humans|Female|Male|*Genome-Wide Association Study|*Leptin|*Cardiovascular Diseases|*Risk Factors|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 29 COBLL1 31739742 Circ. Res. 2019 10.1161/CIRCRESAHA.119.315246 2 0 0 74 29 COBLL1 31533811 BMC Res Notes 2019 PMC6749776 10.1186/s13104-019-4625-1 0 0 0 74 Humans|Female|Pregnancy|*Fetal Macrosomia|Case-Control Studies|Prospective Studies|Dystocia|Birth Weight|*Pregnancy Complications|Gestational Age|Prenatal Diagnosis|Labor, Obstetric|TYRP1 protein, human|*Membrane Glycoproteins|*Biomarkers|*Screening|Risk Factor 29 COLQ 31831253 J Clin Neurosci 2019 10.1016/j.jocn.2019.12.007 0 0 0 91 Child|Humans|*Myasthenic Syndromes, Congenital|*Receptors, Cholinergic|Myasthenia Gravis|Neuromuscular Junction|Acetylcholinesterase|Cholinesterase Inhibitors|Autoantibodies|Muscle Proteins|Phenotype|COLQ protein, human|Collagen 178 COLQ 31773638 Acta Neurol Belg 2019 10.1007/s13760-019-01246-9 0 1 0 91 Child|Humans|*Myasthenic Syndromes, Congenital|*Follow-Up Studies|Turkey|Neuromuscular Junctions|Receptors, Cholinergic|Acetylcholinesterase|Mutation|Phenotype|Receptors, Nicotinic|Muscle Proteins|Family|Collagen|Ephedrine|CHRNE protein, human 178 COLQ 31769119 J. Vet. Intern. Med. 2019 PMC6979411 10.1111/jvim.15667 1 0 0 91 Animals|Dogs|*Myasthenic Syndromes, Congenital|Muscle Proteins|Acetylcholinesterase|Mutations|Breeding|Collagen 178 COLQ 31220253 Hum. Mol. Genet. 2019 PMC6606850 10.1093/hmg/ddz059 4 0 0 91 Humans|Mice|Animals|*Salbutamol|Endplate Acetylcholinesterase Deficiency|Myasthenic Syndromes, Congenital|*Neuromuscular Junction|Receptors, Cholinergic|*Lambert-Eaton Myasthenic Syndrome|Adrenergic beta-2 Receptor Agonists|*Disease Models, Animal|Muscle Proteins|Synaptic Transmission|Acetylcholinesterase|Muscle Fibers, Skeletal|Signal Transduction|Ephedrine|*Muscle Weakness|COLQ protein, human|Collagen|Colq protein, mouse 178 COLQ 31175885 Toxicology 2019 10.1016/j.tox.2019.06.003 0 0 0 91 Animals|Mice|*Cholinesterase Inhibitors|*Acetylcholine|Acetylcholinesterase|Neuromuscular Junction|Synaptic Transmission|Synapses|*Reflex|Muscle Proteins|Bungarotoxins|Muscles|*Respiratory Insufficiency 178 COLQ 31100272 Chem. Biol. Interact. 2019 10.1016/j.cbi.2019.05.018 0 0 0 91 Pregnancy|Female|Rats|Mice|Animals|*Tetrachlorodibenzo-p-dioxin|*Acetylcholinesterase|AHR protein, human|Aryl Hydrocarbon Receptor|Basic Helix-Loop-Helix Transcription Factors|*Cell Differentiation|*Myogenesis|Cytochrome P-450 CYP1A1|*Myotubes|*Myocytes, Cardiac|mRNA|Neurons|*Muscle Contraction 178 COLQ 31048702 Nat Rev Dis Primers 2019 10.1038/s41572-019-0079-y 16 0 0 91 Humans|Aged|Quality of Life|MUSK protein, human|Receptors, Cholinergic|*Myasthenia Gravis|Receptor Protein-Tyrosine Kinases|Agrin|Thymectomy|LDL-Receptor Related Proteins|Autoantibodies|Immunoglobulins, Intravenous|Plasma Exchange 178 COLQ 30898524 Neuromuscul. Disord. 2019 10.1016/j.nmd.2019.02.004 0 0 0 91 Adult|Child|Humans|Adolescent|Young Adult|Middle Aged|*Myasthenic Syndromes, Congenital|*Autonomic Nervous System|*Heart|Heart Rate|Electrocardiography|Cardiac Arrhythmias|Autonomic Nervous System Diseases|Acetylcholinesterase 178 COLQ 30859671 Haemophilia 2019 PMC6850762 10.1111/hae.13698 1 0 0 91 Young Adult|Humans|Quality of Life|Netherlands|Health Status|Absenteeism|Employment|Surveys and Questionnaires|Efficiency|*Blood Coagulation Disorders 178 COLQ 30847606 J Patient Rep Outcomes 2019 PMC6405782 10.1186/s41687-019-0106-5 0 0 0 91 Adolescent|Infant, Newborn|Pregnancy|Female|Infant|Young Adult|Humans|Adult|*Cohort Studies|Netherlands|*Infant, Extremely Premature|*Very Low Birth Weight|Questionnaire|*Parturition|Quality of Life|Peer Group 178 COLQ 30808424 Orphanet J Rare Dis 2019 PMC6390566 10.1186/s13023-019-1025-5 4 24 0 91 *Myasthenic Syndromes, Congenital|Neuromuscular Junction|Synaptic Transmission|Muscle Proteins|Mutation 178 cornulin 31284225 Res. Vet. Sci. 2019 10.1016/j.rvsc.2019.06.008 1 0 0 53 Swine|Animals|*Saliva|*Nose|*Salivary Proteins|Electrophoresis, Gel, Two-Dimensional|Swine Diseases|Proteomics|Biomarkers|Specimen Handling|Stress, Physiological|*Movement Disorders 27 cornulin 30928326 Oral Surg Oral Med Oral Pathol Oral Radiol 2019 10.1016/j.oooo.2019.02.003 0 0 0 53 *Precancerous Conditions|Mouth Neoplasms|Oral Mucosa|Carcinoma, Squamous Cell|Immunohistochemistry|Carcinoma in Situ|Biomarkers, Tumor|Hyperplasia|*Oral Ulcer 27 COX6A2 31155743 Ann. Neurol. 2019 10.1002/ana.25517 0 1 0 26 *Cytochrome-c Oxidase Deficiency|Electron Transport Complex IV|Muscle, Skeletal|Mitochondrial Proteins|Mutation 24 COX6A2 30705335 Sci Rep 2019 PMC6355796 10.1038/s41598-018-37715-z 4 0 0 26 Cattle|Animals|Mice|*Transcriptome|*Prion Disease|*Hippocampus|*Neurons|*Cerebellum|Scrapie|Bovine Spongiform Encephalopathy|Astrocytes|Laser Capture Microdissection|Pyramidal Neurons|Microglia|Synapse|Gene Expression Profiling|Brain 24 COX7A1 31703168 Circ Genom Precis Med 2019 10.1161/CIRCGEN.118.002489 0 0 0 25 *Heart Failure|*Echocardiography|Stroke Volume|Ventricular Function, Left|Heart Ventricles|*Framingham Heart Study|Heart 55 COX7A1 31692088 J. Cell. Biochem. 2019 10.1002/jcb.29539 0 8 0 25 *Adipocytes, Brown|*Hot Temperature|SMAD7 protein, human|*Smad7 Protein|*Cell Differentiation|UCP1 protein, human|Uncoupling Protein 1|*Mitochondria|Thermogenesis|Adipogenesis|MicroRNAs|*Body Temperature Regulation|Signal Transduction|Oxygen Consumption|peroxisome-proliferator-activated receptor-gamma coactivator-1|Transcription Factors|Oxidative Stress 55 COX7A1 31663688 Cancer Med 2019 PMC6912042 10.1002/cam4.2659 1 1 0 25 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Autophagy|Apoptosis|A549 Cells|Cell Proliferation|Viability, Cell|Cell Line, Tumor|Reactive Oxygen Species|Downregulation|Upregulation 55 COX7A1 31048716 Sci Rep 2019 PMC6497719 10.1038/s41598-019-43410-4 0 3 0 25 Mice|Animals|*Adipogenesis|*Mitochondria|UCP1 protein, human|Uncoupling Protein 1|Brown Adipocyte|Mitochondrial Proteins|Gene Expression Regulation|3T3-L1 Cells|Cell Differentiation|Mitochondrial Biogenesis|mRNA|Cytosol 55 COX7A1 30626254 J. Toxicol. Environ. Health Part A 2019 10.1080/15287394.2018.1551645 0 0 0 25 Humans|*Lung Adenocarcinoma|Lung Cancer|DNA Methylation|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|MicroRNAs|Biomarkers, Tumor|Carcinoma, Squamous Cell|Carcinogenesis|HOXA5 protein, human|Homeodomain Proteins|Computational Biology|Genes, Regulator|Genes, Homeobox|Downregulation 55 COX7A1 30616682 Stem Cell Res Ther 2019 PMC6323697 10.1186/s13287-018-1087-7 1 0 0 25 Adult|Humans|*Adipocytes, Brown|*Pluripotent Stem Cells|Adipocytes, White|*Cells, Cultured|Uncoupling Protein 1|Cell Differentiation|*Cell Lines|Brown Fat|Thermogenesis|Adipogenesis|Mitochondrial Proteins|Transcription Factors 55 CPA4 31424161 J. Cell. Mol. Med. 2019 PMC6787466 10.1111/jcmm.14541 3 2 0 103 *Prognosis|*Glioma|mRNA|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|RNAs, Circular|*Neoplastic Processes|Gene Regulatory Networks|Cell Line, Tumor|Up-Regulation|Signal Transduction 37 CPA4 31397502 Mol. Carcinog. 2019 PMC6851884 10.1002/mc.23095 3 2 0 103 AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Down-Regulation|*Nonsmall Cell Lung Cancer|Lung Cancer|Cell Proliferation|Signal Transduction|Cell Line, Tumor|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Transformation, Neoplastic|Gene Knockdown Techniques|Tumorigenesis|Carboxypeptidases A 37 CPA4 31303763 Onco Targets Ther 2019 PMC6610299 10.2147/OTT.S206517 0 3 0 103 *Carcinoma, Hepatocellular|*5 Fluorouracil|*Liver Neoplasms|*Cell Proliferation|*Antibodies, Monoclonal|Antimetabolites, Antineoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|Apoptosis|Thymidylate Synthase 37 CPA4 31279884 Int. J. Biol. Macromol. 2019 10.1016/j.ijbiomac.2019.07.028 2 3 0 103 Mice|Animals|*Pathways, ERK|Mice, Nude|STAT3 protein, human|*STAT3 Transcription Factor|*Colorectal Cancer|*Cell Proliferation|*Signal Transduction|Apoptosis|Up-Regulation|Tumorigenesis|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|*Cell Cycle|Biomarkers, Tumor|*Colonic Neoplasms|Gene Knockdown Techniques|Cell Transformation, Neoplastic 37 CPA4 31273587 J. Assist. Reprod. Genet. 2019 PMC6707954 10.1007/s10815-019-01505-x 1 0 0 103 Humans|Male|*Cryoprotective Agents|*Vitrification|Sperm Motility|*Cryopreservation|*Spermatozoa|Semen Preservation|DNA Fragmentation|Freezing|Sucrose 37 CPA4 31082282 Environ. Health Perspect. 2019 PMC6791491 10.1289/EHP4264 0 0 0 103 Male|Humans|Pregnancy|Female|*Cadmium|*Placenta|*Birth|Fetal Growth|Maternal Exposure|Birth Weight|Environmental Pollutants|Cohort Studies|*Delivery, Obstetric 37 CPA4 31058377 Int J Exp Pathol 2019 PMC6540673 10.1111/iep.12315 3 3 0 103 Mice|Animals|*Carcinoma, Hepatocellular|*Liver Cancer|Mice, Nude|Cell Proliferation|HepG2 Cells|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Neoplastic Stem Cells|Downregulation|Gene Knockdown Techniques|Carboxypeptidases A|Signal Transduction 37 CPA4 30875843 Biomolecules 2019 PMC6468575 10.3390/biom9030103 1 0 0 103 Humans|Female|*Prognosis|Carboxypeptidases A|Biomarkers, Tumor|Cell Line, Tumor|Cell Proliferation 37 CPA4 30628666 Int. J. Oncol. 2019 PMC6365037 10.3892/ijo.2019.4675 3 0 0 103 Humans|*Triple-Negative Breast Cancer|Prognosis|Cancer Stem Cell|Immunohistochemistry|progesterone receptor B|Progesterone Receptor|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|EGFR protein, human|Epidermal Growth Factor Receptor|Cell Proliferation|Cell Line, Tumor|Receptors, Estrogen|Downregulation|Short Hairpin RNA|*Phenotype|RNA Interference|Carboxypeptidases 37 CPA6 31612389 Curr Med Sci 2019 10.1007/s11596-019-2098-z 0 1 0 44 Mice|Animals|*Carcinoma, Hepatocellular|*Proto-Oncogene Proteins c-akt|*Liver Neoplasms|*Signal Transduction|*Up-Regulation|Gene Expression Regulation, Neoplastic|Phosphatidylinositol 3-Kinases|Cell Movement|Cell Proliferation|Prognosis|MicroRNAs|Cell Line, Tumor|Xenograft Model Antitumor Assays|*Transcriptional Activation|Mice, Nude|Apoptosis|shRNA|Carboxypeptidases 24 CPA6 32207733 Zh Nevrol Psikhiatr Im S S Korsakova 2019 10.17116/jnevro201911911265 0 0 0 44 Temporal epilepsy, familial|Epilepsy, Temporal Lobe|*Vestibular Seizures|Electroencephalography|Wakefulness|Sleep|Mutation 24 CPEB1 31521690 Life Sci. 2019 10.1016/j.lfs.2019.116874 0 10 0 510 oxidized low density lipoprotein|*Sirtuin 1|*Lipoproteins, LDL|Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1|*Signal Transduction|*Apoptosis|Human Umbilical Vein Endothelial Cells|*Inflammation|Atherosclerosis|*Protective Agents|Oxidative Stress 208 CPEB1 31374971 Animals (Basel) 2019 PMC6720638 10.3390/ani9080518 1 0 0 510 Swine|Animals|*Breeding|*Homozygote|Inbreeding|Genetics, Population|Genome|Genotype|Genomics|Genetic Variation|Polymorphism, Single Nucleotide 208 CPEB1 31253357 Br J Anaesth 2019 PMC6676161 10.1016/j.bja.2019.05.027 1 1 0 510 Rats|Animals|*Morphine|mitochondrial calcium uniporter|*Drug Tolerance|*Spinal Cord Dorsal Horn|*Calcium Channels|Analgesics, Opioid|Hyperalgesia|Pain|Rats, Sprague-Dawley|Injections, Spinal|Pain Measurement|Cyclic AMP Response Element-Binding Protein|CPEB1 protein, rat|RNA-Binding Proteins 208 CPEB1 30763690 Mol. Cell. Neurosci. 2019 10.1016/j.mcn.2019.02.002 0 0 0 510 Humans|Mice|Animals|*Down Syndrome|*Human Induced Pluripotent Stem Cells|*Hippocampus|*Neurons|Synaptic Plasticity|Dendrites|*Disease Models, Animal|Trisomy|microtubule-associated protein 1B|Microtubule-Associated Proteins|CaM KII|Memory|Cells, Cultured|CPEB1 protein, human|Transcription Factors|mRNA Cleavage and Polyadenylation Factors|Cpeb1 protein, mouse 208 CPEB1 30731077 Brain Res. 2019 10.1016/j.brainres.2019.02.001 0 2 0 510 Humans|Mice|Animals|*Visceral Pain|*Gyrus Cinguli|Polyadenylation|mRNA Cleavage and Polyadenylation Factors|AMPA Receptor|Transcription Factors|mRNA|Disease Models, Animal|Zymosan|Irritable Bowel Syndrome|shRNA|Cytoplasm|Anxiety|Disks Large Homolog 4 Protein|CPEB1 protein, human|Cpeb1 protein, mouse 208 CPEB1 30689869 Hum. Reprod. 2019 PMC6389867 10.1093/humrep/dey389 2 0 0 510 Humans|Female|*Primary Ovarian Insufficiency|*Menopause, Premature|DNA Copy Number Variations|Ovary|Comparative Genomic Hybridization|Mutation|Cohort Studies|Phenotype 208 CPEB2 31616934 Biol. Reprod. 2019 10.1093/biolre/ioz196 1 1 0 109 Humans|Pregnancy|Female|*Trophoblasts|*Pre-Eclampsia|*Hypoxia-Inducible Factor 1|Placenta|RNA, Micro|mRNA|3' Untranslated Region|Transcription, Genetic|Up-Regulation|*Cytoplasm|Polyadenylation|Basic Helix-Loop-Helix Transcription Factors|Hypoxia|CPEB2 protein, human|RNA-Binding Proteins|MIRN210 microRNA, human 40 CPEB2 31589365 Mol. Reprod. Dev. 2019 10.1002/mrd.23278 1 0 0 109 Humans|Male|Rats|Animals|*Sperm|Spermatids|Spermatocytes|Spermatogenesis|*Meiosis|*Gene Expression|Infertility, Male|Transcriptome Analysis|Meiotic Prophase I|Massively Parallel Sequencing|DPF3 protein, human|DNA-Binding Proteins|Transcription Factors|LY6K protein, human|Antigens, Ly|GPI-Linked Proteins|CPEB2 protein, human|RNA-Binding Proteins 40 CPEB2 31185986 BMC Cancer 2019 PMC6558855 10.1186/s12885-019-5771-5 1 0 0 109 Humans|*Polyadenylation|MicroRNAs|*Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|*Cells, Epithelial|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Anoikis|Triple-Negative Breast Cancer|Cyclooxygenase 2|Proto-Oncogene Proteins c-akt|Cell Movement|Upregulation|CPEB2 protein, human|RNA-Binding Proteins|MIRN655 microRNA, human 40 CPEB2 31138601 Mol. Cancer Res. 2019 PMC6726571 10.1158/1541-7786.MCR-18-1291 1 1 0 109 Humans|*Alternative Splicing|*Polyadenylation|SRSF3 protein, human|*Serine-Arginine Splicing Factors|RNA-Binding Proteins|Exon|Triple-Negative Breast Cancer|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Arginine|Serine|CPEB2 protein, human 40 CPEB2 31039976 Reprod. Fertil. Dev. 2019 10.1071/RD18098_CO 0 1 0 109 Animals|Swine|*Polyadenylation|TJP1 protein, human|Tight Junction Protein 1|Occludin|Morula|Blastocyst|Embryonic Development|Tight Junctions|RNA Binding Protein|RNA, Messenger|Oocytes|Gene Expression Regulation, Developmental|3' Untranslated Region|Epithelium 40 CPEB2 30888555 Mol. Biol. Rep. 2019 10.1007/s11033-019-04663-4 1 0 0 109 Humans|*Prognosis|Bayes Theorem|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Receptors, Estrogen|Gene Expression Profiling|Biomarkers, Tumor|Protein Interaction Maps|Computational Biology|mRNA|Transcriptome|Kaplan-Meier Estimate|CPEB2 protein, human|RNA-Binding Proteins|ANXA9 protein, human|Annexins 40 CPEB3 31872260 Nucleic Acids Res. 2019 PMC7026644 10.1093/nar/gkz1192 0 0 0 216 Humans|*Base Pairing|*RNA|Ribozymes|Nucleic Acid Conformation|Genome, Human|*Mutations|PCR|Catalysis|CPEB3 protein, human|RNA-Binding Proteins 69 CPEB3 31416913 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6731686 10.1073/pnas.1815275116 2 4 0 216 *mRNA|CPEB3 protein, human|*RNA-Binding Proteins|Synaptic Plasticity|Hippocampus|Neurons|Synapses|Protein Biosynthesis|Sumoylation|Memory|Cells, Cultured 69 CPEB3 31335995 Cancer Sci. 2019 PMC6726690 10.1111/cas.14138 6 0 0 216 Humans|*Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|RNA, Long Noncoding|MicroRNAs|mRNA|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate|Receiver Operating Characteristic|Risk Factors|ITM2A protein, human|Membrane Proteins|CPEB3 protein, human|RNA-Binding Proteins|STRN3 protein, human 69 CPEB3 31321712 Hepatol Int 2019 PMC6744548 10.1007/s12072-019-09962-3 4 0 0 216 *Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate|ROC Curve|Risk Factors 69 CPEB3 31310044 Cell Prolif. 2019 PMC6797506 10.1111/cpr.12615 6 5 0 216 Humans|*RNA, Long Noncoding|*Glioma|CPEB3 protein, human|*RNA-Binding Proteins|Antagomirs|MicroRNAs|Brain Neoplasms|Cell Proliferation|*Disease Progression|RNA Interference|RNA, Small Interfering|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|Up-Regulation 69 CPEB3 30834603 J. Cell. Biochem. 2019 10.1002/jcb.28528 3 2 0 216 Humans|Female|*miRNA|CPEB3 protein, human|*RNA-Binding Proteins|EGFR protein, human|*Epidermal Growth Factor Receptor|*Ovarian Cancer|Gene Expression Regulation, Neoplastic|Cystadenocarcinoma, Serous|Cell Proliferation|Cell Movement|Downregulation|Upregulation|Oncogenesis|Apoptosis|*Neoplastic Processes|Cell Line, Tumor|Small Noncoding RNA 69 CPEB3 30799082 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.02.006 1 4 0 216 Humans|*RNA, Long Noncoding|*Colorectal Cancer|*Apoptosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|CPEB3 protein, human|*RNA-Binding Proteins|Prognosis|Cell Line, Tumor|Upregulation|Epigenesis, Genetic|Cell Cycle|*Colonic Neoplasms|*Epigenetic 69 CPEB3 30662713 R Soc Open Sci 2019 PMC6304141 10.1098/rsos.180336 0 0 0 216 Animals|*Prions|mRNA Cleavage and Polyadenylation Factors|Drosophila Proteins|Memory|Drosophila|Synapse|RNA Binding Protein|Neurons|Aplysia|Protein Isoforms|Transcription Factors|Amyloid|mRNA Translation|Learning|*Longitudinal Studies 69 CPEB4 31839038 Zhongguo Shi Yan Xue Ye Xue Za Zhi 2019 10.19746/j.cnki.issn.1009-2137.2019.06.012 0 0 0 206 Humans|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|*Apoptosis|K562 Cells|Fusion Proteins, bcr-abl|Cell Proliferation|RNA, Small Interfering|Transfection|RNA, Messenger|CPEB4 protein, human|RNA-Binding Proteins 83 CPEB4 31810463 BMC Genomics 2019 PMC6898931 10.1186/s12864-019-6270-4 0 0 0 206 Animals|Cattle|*Genome-Wide Association Study|Australia|Quantitative Trait Loci|Phenotype|Genotype|Animal Feed|Single Nucleotide Polymorphisms|Eating|*Gene Expression|Body Weight 83 CPEB4 31770107 Aging (Albany NY) 2019 PMC6914387 10.18632/aging.102455 1 6 0 206 *RNA, Long Noncoding|*Glioma|*Apoptosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Temozolomide|Signal Transduction|*Drug Resistance 83 CPEB4 30728769 Front Behav Neurosci 2019 PMC6351472 10.3389/fnbeh.2019.00005 0 1 0 206 Mice|Animals|Olfactory Bulb|*Smell|*Cytoplasmic Granules|Neurogenesis|Neurons|Subventricular Zone|Interneurons|Cell Movement|Mice, Knockout|Odors|*B Cells|Progenitor Cells|Cell Count|Cpeb4 protein, mouse|RNA-Binding Proteins 83 CPEB4 30616374 Am J Rhinol Allergy 2019 10.1177/1945892418823388 1 2 0 206 *Computational Biology|*Rhinitis, Allergic, Seasonal|Gene Regulatory Networks|ABCA1 protein, human|*ATP Binding Cassette Transporter 1|Gene Expression Profiling|Protein Interaction Maps|MicroRNAs|Gene Expression Regulation, Neoplastic|Down-Regulation|Up-Regulation|Transcription Factors 83 CPVL 31692310 Minerva Pediatr. 2019 10.23736/S0026-4946.19.05592-0 0 0 0 67 Pregnancy|Infant|Humans|Female|Infant, Newborn|*Infant, Premature|*Infant, Very Low Birth Weight|*Infant, Premature, Diseases|Infant Mortality|Multiple Pregnancy 65 CPVL 31621275 Minerva Pediatr. 2019 10.23736/S0026-4946.19.05551-8 0 0 0 67 Pregnancy|Infant|Humans|Female|Infant, Newborn|*Leukomalacia, Periventricular|*Maternal Age|*Infant, Premature|*Infant, Premature, Diseases|*Infant, Very Low Birth Weight|Gestational Age|Obstetric Labor, Premature|Fetal Membranes, Premature Rupture|Birth Weight|Cerebral Hemorrhage 65 CPVL 31541464 Epilepsia 2019 10.1111/epi.16340 0 0 0 67 Infant|Humans|Child|Infant, Newborn|*Infant, Premature, Diseases|*Infant, Very Low Birth Weight|Infant, Extremely Premature|Gestational Age|Retinopathy of Prematurity|Cerebral Hemorrhage|*Epilepsy|Incidence 65 CRELD1 31759545 Taiwan J Obstet Gynecol 2019 10.1016/j.tjog.2019.09.024 0 0 0 38 Pregnancy|Female|Humans|Amniocentesis|*Congenital Heart Defects|Prenatal Diagnosis|Karyotyping|*Fetus|Comparative Genomic Hybridization|Ultrasonography, Prenatal 32 CRIP1 31873850 Infection 2019 10.1007/s15010-019-01383-6 0 0 0 104 Humans|*C-Reactive Protein|*Diagnosis, Differential|*Kinetics|*Infections, Viral|Bacterial Infections|Biomarkers|Sensitivity and Specificity|*Bacteria|Emergency Department 80 CRIP1 31614728 Molecules 2019 PMC6832298 10.3390/molecules24203672 1 1 0 104 TYRP1 protein, human|*Membrane Glycoproteins|Carrier Proteins|Endocannabinoids|Cannabinoids|Signal Transduction|IgA receptor 80 CRIP1 31577790 Med. Sci. Monit. 2019 PMC6790098 10.12659/MSM.918092 0 0 0 104 Humans|*Networks, Gene|*Prognosis|*Cysteine|U937 Cells|*Leukemia, Myeloid, Acute|RNA, Long Noncoding|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Relapse|Survival Analysis|Cell Proliferation|Cell Line, Tumor|shRNA|Bone Marrow|CRIP1 protein, human|Carrier Proteins|LIM Domain Proteins 80 CRIP1 31412637 Genes (Basel) 2019 PMC6723724 10.3390/genes10080611 3 0 0 104 Mice|Animals|*Clustering|Sequencing, RNA|Single-Cell Analysis|Algorithm|Software|Computational Biology|Gene Expression Profiling|scRNA|Base Sequence|Genetic Markers 80 CRIP1 31312368 Am J Transl Res 2019 PMC6614615 0 8 0 104 *Cysteine|*Colorectal Cancer|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Cell Movement|Cell Proliferation|Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Oncogene|*Colonic Neoplasms|Zinc|Dietary Supplements 80 CRIP1 30850009 J. Exp. Clin. Cancer Res. 2019 PMC6408822 10.1186/s13046-019-1117-z 1 37 0 104 Humans|*5 Fluorouracil|*Cysteine|*Ubiquitin|*Colorectal Cancer|*Apoptosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Drug Resistance, Neoplasm|*Colonic Neoplasms|Xenograft Model Antitumor Assays|Signal Transduction|CRIP1 protein, human|Carrier Proteins|LIM Domain Proteins 80 CRIP1 30833559 Nat Commun 2019 PMC6399272 10.1038/s41467-019-08950-3 4 49 0 104 *Candida albicans|*Toll-Like Receptor 2|Systemic candidiasis|*Candidiasis|Toll-Like Receptor 4|Immunity, Innate|Cytokines|Receptors, Pattern Recognition|NF-kappa B|small protein B|*RNA-Binding Proteins|CRIP1 protein, human|Carrier Proteins|Signal Transduction|Receptors, C-Type Lectin|LIM Domain Proteins 80 CRIP1 30809628 Alcohol Alcohol. 2019 10.1093/alcalc/agz002 1 0 0 104 *Self Report|*Follow-Up Studies|*Depression|*Alcohol Consumption|gamma-Glutamyltransferase|Alcoholism|Aspartate Aminotransferases|Alanine Transaminase|Transferrin|*Biomarkers|Erythrocyte Indices 80 CRNN 31443700 BMC Cancer 2019 PMC6708230 10.1186/s12885-019-6059-5 2 1 0 53 Humans|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Prognosis|Carcinoma, Squamous Cell|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Transcriptome|Kaplan-Meier Estimate 59 CRNN 31258998 AMIA Jt Summits Transl Sci Proc 2019 PMC6568107 0 0 0 53 *Electronic Mail|Perceptron|Machine Learning|Algorithms|*Biological Phenomena 59 CRNN 31234850 Respir. Res. 2019 PMC6591972 10.1186/s12931-019-1101-3 2 2 0 53 *Azithromycin|*Multivesicular Bodies|Anti-Bacterial Agents|Respiratory Mucosa|Bronchi|Cystic Fibrosis|*Epithelium|Epithelial Cells|Cell Line|*Cell Differentiation|Tumor Necrosis Factor-alpha 59 CRNN 31208007 Sensors (Basel) 2019 PMC6631336 10.3390/s19122695 1 0 0 53 *Neural Networks, Computer|Acoustic|Algorithms|Noise|Normal Distribution|Sound 59 CRNN 30905748 Methods 2019 10.1016/j.ymeth.2019.03.014 0 0 0 53 *Histone Code|*Neural Network Model|Histone|Enhancer Elements, Genetic|Epigenetic|*Protein Processing, Post-Translational|Computational Biology|Machine Learning|Databases, Genetic 59 CROCC 31799620 Biosci. Rep. 2019 PMC6954365 10.1042/BSR20190108 0 14 0 82 *Epithelial-Mesenchymal Transition|*Gallbladder Neoplasms|*Up-Regulation|*Downregulation|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|CDH1 protein, human|N-Cadherin|Cell Movement|Cell Line, Tumor|Vimentin|*Transcriptional Activation|Antigens, CD 32 CROCC 30852641 Virchows Arch. 2019 10.1007/s00428-019-02554-4 1 0 0 82 Humans|Aged|*Pseudopodia|*Extracellular Space|SMARCB1 protein, human|SMARCB1 Protein|*Colorectal Carcinoma|Rhabdoid Tumor|DNA-Binding Proteins|Transcription Factors|Chromosomal Proteins, Non-Histone|Biomarkers, Tumor|Chromatin Assembly and Disassembly|*Electron Microscopy|Phenotype 32 CRYBB2 31523120 Mol. Vis. 2019 PMC6707615 0 0 0 149 Humans|*Cataract|gamma-Crystallins|*Mutation|*Chinese|DNA Mutational Analysis|Pedigree|Heterozygote|Base Sequence|Mutation, Missense 99 CRYBB2 31479653 Exp. Eye Res. 2019 PMC6867612 10.1016/j.exer.2019.107787 1 0 0 149 Humans|Mice|Cats|Animals|*Lens, Crystalline|Cataract|*Cell Line|Eye Proteins|Epithelial Cells|Genes, Homeobox|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Gene Expression|*Epithelium|RNA, Messenger|Cells, Cultured|Membrane Proteins|INPPL1 protein, human|Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|Inppl1 protein, mouse 99 CRYBB2 30842085 Br J Ophthalmol 2019 PMC6678048 10.1136/bjophthalmol-2017-310416 0 0 0 149 *Exfoliation Syndrome|*Aqueous Humor|*Proteomics|*Eyes|Glaucoma, Open-Angle|Cataract|Proteins 99 CRYBB2 30706176 J. Neurooncol. 2019 PMC6450757 10.1007/s11060-019-03110-5 2 0 0 149 Humans|*Glioblastoma|*Genetic Markers|Gliomas|Brain Neoplasms|Isocitrate Dehydrogenase|Gene Expression Regulation, Neoplastic|African Americans|Mutation|Tretinoin 99 CRYBB3 31523120 Mol. Vis. 2019 PMC6707615 0 0 0 14 Humans|*Cataract|gamma-Crystallins|*Mutation|*Chinese|DNA Mutational Analysis|Pedigree|Heterozygote|Base Sequence|Mutation, Missense 36 CRYBB3 30646012 Invest. Ophthalmol. Vis. Sci. 2019 PMC6336207 10.1167/iovs.18-25921 1 0 0 14 Animals|*mRNA|*Lens, Crystalline|beta-Crystallin B Chain|Crystallin|Cataract|Cell Differentiation|Pedigree|Gene Expression|Organogenesis 36 CRYGC 31523120 Mol. Vis. 2019 PMC6707615 0 0 0 132 Humans|*Cataract|gamma-Crystallins|*Mutation|*Chinese|DNA Mutational Analysis|Pedigree|Heterozygote|Base Sequence|Mutation, Missense 65 CRYGC 31302914 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.07.010 0 0 0 132 Humans|*Pedigree|gamma-Crystallins|*Cataract|Chinese|DNA Mutational Analysis|Genes, Dominant|Genetic Predisposition to Disease|Codon, Nonsense|Mutation|Crygc protein, human 65 CRYGD 31758928 Arch. Biochem. Biophys. 2019 10.1016/j.abb.2019.108204 0 1 0 30 Humans|*Tryptophan|hesperetin|gamma-Crystallins|*Hesperidin|Lens, Eye|*Oxidation-Reduction|Amino Acid Sequence|Models, Molecular|Spectrometry, Fluorescence|Fluorescence 154 CRYGD 31523120 Mol. Vis. 2019 PMC6707615 0 0 0 30 Humans|*Cataract|gamma-Crystallins|*Mutation|*Chinese|DNA Mutational Analysis|Pedigree|Heterozygote|Base Sequence|Mutation, Missense 154 CRYGD 31393108 Biochemistry 2019 10.1021/acs.biochem.9b00208 1 0 0 30 154 CRYGD 31003047 Spectrochim Acta A Mol Biomol Spectrosc 2019 10.1016/j.saa.2019.04.013 0 1 0 30 Humans|*Copper|*Rutin|gamma-Crystallins|*Protein Folding|alpha-Crystallin A Chain|Lens Opacity|Lens, Crystalline|Protein Conformation|Protein Binding|Protein Aggregates|*Spectroscopy|Oxidation-Reduction|Models, Molecular 154 CRYGD 30851242 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.03.010 0 0 0 30 Humans|Endoplasmic Reticulum|Intracellular Membranes|Cytosol|Recombinant Proteins|HEK293 Cells|TYRP1 protein, human|Membrane Glycoproteins|Topoisomerase II Inhibitors 154 CRYGD 30633517 J Chem Theory Comput 2019 10.1021/acs.jctc.8b00894 0 0 0 30 Humans|Cattle|Animals|*Monte Carlo Method|hen egg lysozyme|Muramidase|Protein Conformation|Molecular Dynamics Simulation|Thermodynamics|Artifacts|Hydrogen-Ion Concentration 154 CRYZ 31872054 Neurol Genet 2019 PMC6878836 10.1212/NXG.0000000000000375 1 0 0 488 Humans|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Amyotrophic Lateral Sclerosis|Genetic Loci 164 CRYZ 31589875 J Pharm Sci 2019 PMC6941222 10.1016/j.xphs.2019.10.004 0 0 0 488 *Rotavirus|*Aluminum|*Rotavirus Vaccines|*Vaccines, Subunit|*Vaccines, Synthetic|*Adjuvants, Immunologic|Alhydrogel|*Antigens|*Adjuvants, Pharmaceutic|Antibodies, Neutralizing|Antibodies, Viral|Enzyme-Linked Immunosorbent Assay|Viral Nonstructural Proteins|Recombinant Fusion Proteins|Immunoglobulin G 164 CRYZ 31400347 J Pharm Sci 2019 PMC6941226 10.1016/j.xphs.2019.08.002 2 0 0 488 Rotavirus B|*Rotavirus|Rotavirus Vaccines|Rotavirus Infections|NS35 protein, rotavirus|Viral Nonstructural Proteins|Antibodies, Neutralizing|Vaccines, Subunit|Antibodies, Viral|RNA-Binding Proteins|Adjuvants, Immunologic|Immunoglobulin G 164 CRYZ 31400346 J Pharm Sci 2019 PMC6941221 10.1016/j.xphs.2019.08.001 2 0 0 488 *Rotavirus|*Rotavirus Vaccines|*Recombinant Fusion Proteins|Antibodies, Neutralizing|Antibodies, Viral|Adjuvants, Immunologic|Viral Nonstructural Proteins|Excipients|Escherichia coli 164 CRYZ 31228583 J Proteomics 2019 10.1016/j.jprot.2019.103422 0 0 0 488 Animals|*Animals, Wild|*Deer|*Proteomics|*Meat|Muscle, Skeletal|Taste|Color|Proteome|*Biomarkers 164 Csde1 31579823 Sci Adv 2019 PMC6760934 10.1126/sciadv.aax2166 0 0 0 287 Synapses|Synaptic Transmission|Nerve Tissue Proteins|Genetic Predisposition to Disease|RNA-Binding Proteins|Heterozygote|Gene Expression Regulation 66 Csde1 31112526 J. Clin. Invest. 2019 PMC6668693 10.1172/JCI124979 4 0 0 287 Humans|*Antibiotic|clofoctol|Neoplasm Recurrence, Local|*Glioma|*Cresols|Brain Neoplasms|Neoplastic Stem Cells|Xenograft Model Antitumor Assays|Cell Line, Tumor|Antineoplastic Agents|Cell Proliferation|Apoptosis|Gene Expression Regulation, Neoplastic|Signal Transduction|Transcription Factors|KLF13 protein, human|Repressor Proteins|Cell Cycle Proteins 66 Csde1 31027221 J Clin Med 2019 PMC6517883 10.3390/jcm8040560 3 2 0 287 66 Csde1 30733278 Biosci. Rep. 2019 PMC6395372 10.1042/BSR20182189 1 8 0 287 *Myosin B|*Spermine Synthase|Myosin Type V|Myosin Heavy Chains|Secretory Vesicles|Protein Binding|Protein Transport|Binding Sites|Biological Transport|Melanocytes|Adaptor Proteins, Signal Transducing|Actin|Yeast Two-Hybrid System 66 Csde1 30710169 Virchows Arch. 2019 10.1007/s00428-018-02516-2 2 0 0 287 Humans|Female|*Endometrial Carcinoma|Carcinoma, Endometrioid|Cystadenocarcinoma, Serous|Adenocarcinoma, Clear Cell|SMARCA4 protein, human|Nuclear Proteins|Transcription Factors|Mutation|PTEN protein, human|PTEN Phosphohydrolase|DNA Mutational Analysis|Genes, Regulator|ARID1A protein, human|Immunohistochemistry|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Microsatellite Instability|Oncogenes 66 CSMD1 31806993 Onco Targets Ther 2019 PMC6839572 10.2147/OTT.S227122 0 0 0 70 Humans|Male|Middle Aged|*Lymphoma, Large B-Cell, Diffuse|*Genomics|Prognosis|Mutations|Myeloid Differentiation Factor 88|Oligonucleotide Array Sequence Analysis|Genes, myc|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Biomarkers, Tumor 142 CSMD1 31664672 Eat Weight Disord 2019 10.1007/s40519-019-00802-9 1 0 0 70 Genome-Wide Association Study|*Anorexia Nervosa|Exome|Genetic Predisposition to Disease|*Dopamine|Phenotype|Exons|*Reward|Neurodevelopmental Disorders 142 CSMD1 31604923 Nat Commun 2019 PMC6789153 10.1038/s41467-019-12522-w 0 0 0 70 Humans|Male|Female|*Infertility, Female|*Mutations|CSMD1 protein, human|Membrane Proteins|Tumor Suppressor Proteins|*Genes, Regulator|Ovary|Testes|Phenotype|Germ Cell 142 CSMD1 31592231 Int. J. Biol. Sci. 2019 PMC6775299 10.7150/ijbs.23802 2 5 0 70 142 CSMD1 31532792 PLoS ONE 2019 PMC6750571 10.1371/journal.pone.0221957 2 0 0 70 Humans|APOL1 protein, human|*Apolipoprotein L1|*Blood Pressure|*Alleles|*Hypertension|Angiotensin II Type 1 Receptor Blockers|Tetrazoles|Antihypertensives|*Hypotension|African Americans|Benzimidazoles|proto-oncogene proteins c-mas-1|*Receptors, G-Protein-Coupled|*Proto-Oncogene Proteins|Angiotensins 142 CSMD1 31439935 Mol. Psychiatry 2019 10.1038/s41380-019-0479-0 3 0 0 70 Humans|Complement C4|*Proteins, Complement|Complement C4a|*Schizophrenia|Genotypes|Complement C4b|Polymorphism, Genetic|Gene Expression 142 CSMD1 31427592 Sci Rep 2019 PMC6700135 10.1038/s41598-019-48229-7 2 0 0 70 *Head and Neck Neoplasms|Head and Neck Squamous Cell Carcinoma|Carcinoma, Squamous Cell|DNA Copy Number Variations|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|*Disease Progression|Lymphatic Metastasis|CCND1 protein, human|Cyclin D1|Mutations|Genes, p16|KMT2D protein, human|DNA-Binding Proteins|Neoplasm Proteins 142 CSMD1 31127295 Hum. Mol. Genet. 2019 PMC6644157 10.1093/hmg/ddz070 2 0 0 70 *Blood Pressure|*Arterial Pressure|*Genome-Wide Association Study|*Epistasis, Genetic|Hypertension|*Smoking|Genetic Loci|Polymorphism, Single Nucleotide|*Tobacco Smoking|Phenotype 142 CSMD1 30987620 BMC Psychiatry 2019 PMC6466712 10.1186/s12888-019-2089-4 1 0 0 70 Humans|Genome-Wide Association Study|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Antipsychotics|Genotype|Case-Control Studies|Risk Factors|CSMD1 protein, human|Membrane Proteins 142 CSMD1 30755830 PeerJ 2019 PMC6368834 10.7717/peerj.6375 7 1 0 70 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Computational Biology|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Biomarkers, Tumor|Protein Interaction Maps|Databases, Genetic|Disease Progression 142 CSMD1 30722798 Psychol Med 2019 10.1017/S0033291719000072 0 0 0 70 *Depressive Disorder, Major|*Whole Exome Sequencing|*Magnetic Resonance Imaging|Gray Matter|Brain|*Psychotherapy 142 CSMD2 31200735 J. 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Cancer Res. 2019 PMC6570863 10.1186/s13046-019-1273-1 3 0 0 9 Humans|*Hepatitis B virus|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Hepatitis B, Chronic|*Hepatitis B Virus Infection|*integration, Viral|DNA, Viral|Liver Cirrhosis|Prognosis|*DNA Viruses 20 CSMD2 31068362 eNeuro 2019 PMC6506821 10.1523/ENEURO.0434-18.2019 1 0 0 9 *Disks Large Homolog 4 Protein|*Membrane Proteins|*Neurogenesis|Guanylate Kinases|Dendritic Spines|Synapses|Nerve Tissue Proteins|Neurons|Excitatory Postsynaptic Potentials|Hippocampus|Intracellular Signaling Peptides and Proteins|Green Fluorescent Proteins|*Transcription Factors|Gene Expression Regulation, Developmental|Cells, Cultured 20 CSMD3 31852448 BMC Genet. 2019 PMC6921553 10.1186/s12863-019-0797-x 0 0 0 6 41 CSMD3 31417239 Drug Des Devel Ther 2019 PMC6594009 10.2147/DDDT.S205633 1 0 0 6 Humans|*Etoposide|*Small Cell Lung Carcinoma|PE regimen|Cisplatin|Lung Neoplasms|Antineoplastic Combined Chemotherapy Protocols|Cell Line, Tumor|Apoptosis|Epirubicin|Mutation 41 CSMD3 31179577 Anim. Genet. 2019 10.1111/age.12805 1 0 0 6 Humans|Cattle|Animals|*Genome-Wide Association Study|*Phenotype|SNPs|Quantitative Trait Loci|Breeding|Genotype|Body Weight|*Chinese|Genes, Regulator 41 CSMD3 31068362 eNeuro 2019 PMC6506821 10.1523/ENEURO.0434-18.2019 1 0 0 6 *Disks Large Homolog 4 Protein|*Membrane Proteins|*Neurogenesis|Guanylate Kinases|Dendritic Spines|Synapses|Nerve Tissue Proteins|Neurons|Excitatory Postsynaptic Potentials|Hippocampus|Intracellular Signaling Peptides and Proteins|Green Fluorescent Proteins|*Transcription Factors|Gene Expression Regulation, Developmental|Cells, Cultured 41 CSMD3 30885352 Lung Cancer 2019 10.1016/j.lungcan.2019.01.003 6 0 0 6 41 CSMD3 30720096 Mol Med Rep 2019 PMC6423600 10.3892/mmr.2019.9902 3 1 0 6 41 CSMD3 30710169 Virchows Arch. 2019 10.1007/s00428-018-02516-2 2 0 0 6 41 CST7 31115549 Oncol. Rep. 2019 PMC6549101 10.3892/or.2019.7154 0 1 0 128 Humans|*Carcinoma, Hepatocellular|*Liver Cancer|*Prospective Studies|Neoplasm Recurrence, Local|*Hepatitis B|Prognosis|Hepatitis B virus|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Nomograms|Bioinformatics|Cystatins 39 CST7 31059105 Oncol. Rep. 2019 PMC6549077 10.3892/or.2019.7135 0 0 0 128 Humans|*Prognosis|*Cystatin B|*Cystatin-2|Quality of Life|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Gene Expression Regulation, Neoplastic|Pancreaticoduodenectomy|Pancreatectomy|Biomarkers, Tumor|*Transcription Factors|Survival Analysis|Nomogram|Cell Line, Tumor 39 CST7 30840596 Radiol Oncol 2019 PMC6411024 10.2478/raon-2019-0007 1 13 0 128 *Cystatin B|*T-Lymphocytes, Cytotoxic|GZMB protein, human|Granzymes|Cathepsin C|Cystatins|Natural Killer Cells|Cathepsin L|Cathepsins|Perforin|Lysosomes|Cell Line|Endosomes|*Transcription Factors 39 CTAGE1 30661054 Gut 2019 10.1136/gutjnl-2018-317619 7 0 0 3 *Genome-Wide Association Study|*Diverticular Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Diverticulitis|Colon|*Connective Tissue 238 CTHRC1 31855733 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109742 0 0 0 293 *Stomach Neoplasms|*Signal Transduction|Cell Migration|Extracellular Matrix Proteins|Cell Proliferation|Cell Line, Tumor|*Hypoxia-Inducible Factor 1|CXCR4 protein, human|Receptors, CXCR4|Gene Expression Regulation, Neoplastic|Upregulation|Set2 protein, human|*Histone-Lysine N-Methyltransferase 169 CTHRC1 31798347 Cancer Cell Int. 2019 PMC6884781 10.1186/s12935-019-1041-5 0 1 0 293 Humans|Prognosis|*Lung Adenocarcinoma|Immunohistochemistry|Carcinoma, Squamous Cell|Biomarkers, Tumor|Extracellular Matrix Proteins|*Neovascularization, Pathologic|Lung Neoplasms|CTHRC1 protein, human 169 CTHRC1 31787549 Reprod. Biomed. Online 2019 10.1016/j.rbmo.2019.10.001 1 2 0 293 Humans|Female|*Wnt Pathway|Cell Movement|beta Catenin|*Catenins|Cell Proliferation|*Stromal Cells|Extracellular Matrix Proteins|Endometrium|RNA, Small Interfering|Cell Line, Tumor|Endometriosis|Disease Progression|Collagen|CTHRC1 protein, human 169 CTHRC1 31615341 RNA Biol 2019 PMC6973307 10.1080/15476286.2019.1673117 1 0 0 293 Humans|*Keratinocytes|*Apoptosis|miRNAs|Downregulation|Carcinoma, Hepatocellular|Cell Proliferation|Liver Neoplasms|Gene Expression Regulation, Neoplastic|Upregulation|Cell Line, Tumor|*Diabetes Mellitus|MIRN98 microRNA, human 169 CTHRC1 31612481 J. Cell. Physiol. 2019 PMC6916361 10.1002/jcp.29067 2 0 0 293 Humans|*Transcriptional Network|*Adenocarcinoma|RNA, Micro|*Colonic Neoplasms|*Disease Progression|Gene Expression Regulation, Neoplastic|RNA, Long Noncoding|Gene Ontology|Gene Expression Profiling|Genes, Regulator|Computational Biology|Transcription Factors|RNA, Messenger|Biomarkers, Tumor|Colon|CTHRC1 protein, human|Extracellular Matrix Proteins 169 CTHRC1 31576140 Onco Targets Ther 2019 PMC6765327 10.2147/OTT.S219429 0 0 0 293 *Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|Extracellular Matrix Proteins|Immunohistochemistry|Cell Movement|Cell Proliferation|Cell Line, Tumor|Biomarkers 169 CTNND2 31814264 Am. J. Med. Genet. 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Genet. 2019 10.1111/age.12739 0 0 0 439 Cattle|Animals|Female|*Buffaloes|*Milk|Genome-Wide Association Study|*Phenotype|Lactation|Breeding|Polymorphism, Single Nucleotide|Genomics 84 CTNND2 30880778 J Cancer Res Ther 2019 10.4103/jcrt.JCRT_634_17 0 9 0 439 *DNA Methylation|*Esophageal Cancer|Esophageal Squamous Cell Carcinoma|*Transforming Growth Factor beta|Promoter Regions, Genetic|Epigenesis, Genetic|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|*Catenins|Down-Regulation|*Epigenetic|beta Catenin|Cell Line, Tumor|Signal Transduction|Immunohistochemistry|India 84 CTNND2 30872378 Mol. 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Dyn. 2019 10.1002/dvdy.64 2 0 0 88 *Cerebellum|*Neurons|Hindbrain|Neurogenesis|Cell Differentiation|Stem Cells|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Gene Expression Regulation, Developmental|Cell Movement|*Brain|Cytoplasmic Granules 128 CUX2 31089300 Nat Hum Behav 2019 10.1038/s41562-019-0557-y 3 0 0 88 Humans|*Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Linkage Disequilibrium|Genetic Loci|*Smoking Behavior|European Continental Ancestry Group|Case-Control Studies|Cigarette Smoking|Risk Factor 128 CUX2 30770393 Development 2019 10.1242/dev.170068 2 3 0 88 LIM-Homeodomain Proteins|Homeodomain Proteins|Telencephalon|Transcription Factors|Gene Expression Regulation, Developmental|*Introns|Neurons|*Regulatory Sequences, Nucleic Acid 128 CUX2 30720667 Pharmacogenet. Genomics 2019 10.1097/FPC.0000000000000370 0 0 0 88 Humans|Genome-Wide Association Study|*Antitubercular Agents|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Chemical and Drug Induced Liver Injury|Haplotypes|Gene Frequency|Genotype|Alleles|Case-Control Studies|Odds Ratio|Prospective Studies|FAM65B protein, human|Proteins 128 CUX2 30651234 Biol Open 2019 PMC6398465 10.1242/bio.040584 0 35 0 88 Animals|Limb Buds|*Forelimb|Homeobox|Body Patterning|Mesoderm|Gene Expression Regulation, Developmental|Hedgehog Proteins|Hindlimbs|*Upper Extremity|Trans-Activators|Vertebrates|In Situ Hybridization 128 CUX2 30636884 Onco Targets Ther 2019 PMC6309779 10.2147/OTT.S185710 1 5 0 88 *Thyroid Cancer, Papillary|Thyroid Cancer|Carcinoma, Papillary|*Oncogene|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Epithelial-Mesenchymal Transition|Cell Line, Tumor 128 CUZD1 31249498 Clin Proteomics 2019 PMC6585069 10.1186/s12014-019-9246-0 2 0 0 24 Humans|*Proteome|Indirect Immunofluorescence|Colitis, Ulcerative|Crohn Disease|Autoantibodies|Self-Antigens|Immunoglobulin A|GPI-Linked Proteins|Biomarkers|Immunoglobulin G|Enzyme-Linked Immunosorbent Assay|Pancreas|Membrane Proteins|*Mass Spectrometry 35 CYP4X1 30755683 Sci Rep 2019 PMC6372685 10.1038/s41598-019-38520-y 1 0 0 8 Humans|Animals|Cattle|Adult|Middle Aged|Aged|Acquired CJD|Creutzfeldt-Jakob Disease, Sporadic|*Creutzfeldt-Jakob Syndrome|Encephalopathy, Bovine Spongiform|Prions|Prion Proteins|*Mutation|*Chinese|Genotype|*Genes, Regulator|Magnetic Resonance Imaging|Onset Age|China 26 CYTL1 31853533 Food Funct 2019 10.1039/c9fo02786f 0 0 0 57 Mice|Animals|guar gum|*Reishi|*Galactans|*Plant Gums|*Mannans|*Colorectal Cancer|Colon|Dietary Fiber|Cecum|*Polysaccharides|*Colonic Neoplasms|*Dietary Carbohydrates|Lipid Metabolism 34 CYTL1 31823178 Inflammation 2019 10.1007/s10753-019-01116-9 0 2 0 57 *Neutrophils|Receptor-2, CC Chemokine|AKT1 protein, human|Protein Kinase B|Cytokines|*Sepsis|Lipopolysaccharides|Chemotaxis|Phagocytosis|Signal Transduction|Reactive Oxygen Species|Upregulation|Phosphorylation 34 CYTL1 31638362 Minerva Med. 2019 10.23736/S0026-4806.19.06166-4 0 0 0 57 *Computational Biology|*Stomach Neoplasms|*Prognosis|Gene Ontology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Databases, Genetic|Biomarkers, Tumor|Transcriptome 34 CYTL1 31089746 Cell. 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Pharmacol. 2019 10.1016/j.bcp.2019.113772 0 0 0 129 Humans|Carcinoma, Non-Small-Cell Lung|*Alleles|Lung Neoplasms|EGFR protein, human|*Epidermal Growth Factor Receptor|*Lung Adenocarcinoma|*Genes, erbB-1|Gefitinib|Protein Kinase Inhibitors|Quinazolines|Drug Resistance, Neoplasm|Prognosis|Cell Line, Tumor|Cell Proliferation|Mutation|DACT2 protein, human|Carrier Proteins|Neoplasm Proteins 53 DACT2 31531376 Mol Biol Res Commun 2019 PMC6715267 10.22099/mbrc.2019.33006.1393 0 1 0 129 Iran|Methylenetetrahydrofolate Reductase (NADPH2)|Colorectal Cancer|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|DNA Methylation|Genotype|Adenocarcinoma|Epigenesis, Genetic|Colonic Neoplasms|Case-Control Studies 53 DACT2 30694715 Am. J. Respir. Cell Mol. Biol. 2019 PMC6503619 10.1165/rcmb.2018-0384OC 1 1 0 129 Humans|*Genome-Wide Association Study|Pulmonary Disease, Chronic Obstructive|Genetic Predisposition to Disease|Genetic Loci|Polymorphism, Single Nucleotide|Smoking|Lung|European Continental Ancestry Group 53 DAOA 31455759 Transl Psychiatry 2019 PMC6711957 10.1038/s41398-019-0532-4 0 0 0 34 Genome-Wide Association Study|*Schizophrenia|Linkage Disequilibrium|SNPs|Genetic Predisposition to Disease|Gene Frequency|Genotype|Methylenetetrahydrofolate reductase deficiency|Psychotic Disorders|Genetic Variation|*Knowledgebase|Homocystinuria|Muscle Spasticity|Methylenetetrahydrofolate Reductase (NADPH2) 168 DAOA 30719257 Basic Clin Neurosci 2019 PMC6359688 10.32598/bcn.9.6.429 0 0 0 34 Catechol O-Methyltransferase|Gene Frequency|Bipolar Disorder|Schizophrenia|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Case-Control Studies|Carrier Proteins|Intracellular Signaling Peptides and Proteins 168 DAZ1 31134133 Front Genet 2019 PMC6514098 10.3389/fgene.2019.00427 0 0 0 63 Male|Humans|*Azoospermia|*DNA Copy Number Variations|*Infertility, Male|Oligozoospermia|Chromosomes, Human, Y|Spermatogenesis|Haplotypes|Chromosome Deletion|Asian Continental Ancestry Group 205 DAZ1 31000864 J Pak Med Assoc 2019 0 0 0 63 Humans|Male|Male sterility due to Y-chromosome deletions|Sex Chromosome Disorders of Sex Development|Sex Chromosome Aberrations|*Infertility, Male|Chromosome Deletion|Chromosomes, Human, Y|Oligospermia|*Chromosomal Abnormalities|Azoospermia|Karyotyping|Fertility|Genetic Testing|Pakistan 205 DBR1 31806906 Nat. Med. 2019 10.1038/s41591-019-0672-3 2 1 0 69 Humans|*Encephalitis, Herpes Simplex|*Herpesvirus 1, Human|*Neurons|Toll-Like Receptor 3|Central Nervous System|STAT1 protein, human|STAT1 Transcription Factor|Interferon|Cells, Cultured|Cell-Mediated Immunity|Genetic Predisposition to Disease|Mutation|Antiviral Agents 63 DCHS1 31358536 Development 2019 10.1242/dev.176776 0 1 0 39 Humans|Animals|Mice|*Osteogenesis|Van Maldergem Wetzburger Verloes syndrome|Hand Deformities, Congenital|Foot Deformities, Congenital|Craniofacial Abnormalities|Abnormalities, Multiple|*Cell Differentiation|Intellectual Disability|Signal Transduction|Cadherins|Adaptor Proteins, Signal Transducing|Phosphoproteins|Tumor Suppressor Proteins|Cell Cycle Proteins|Mutations|Joint Instability|DCHS1 protein, human|FAT4 protein, human 40 DCHS1 31028265 Nat Commun 2019 PMC6486645 10.1038/s41467-019-09459-5 3 1 0 39 Humans|Mice|Animals|*Endocardium|Mitral Valve Prolapse|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|*Pluripotent Stem Cells|BMP2 protein, human|Mitral Valve|*Pre-B-Cells|Transforming Growth Factor beta|Epithelial-Mesenchymal Transition|Signal Transduction|Heart Ventricles 40 DCHS1 30858616 Nat. 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Pharmacol. 2019 10.1007/s00210-019-01674-7 0 0 0 0 *Apoptosis|*Necrosis|CASP3 protein, human|Caspase 3|Pyroptosis|Cell Line, Tumor|Cell Death|Genes, Tumor Suppressor|Receptors, Estrogen 79 DFNA5 30976076 Nat Commun 2019 PMC6459836 10.1038/s41467-019-09397-2 20 1 0 0 Mice|Animals|*Inflammasomes|CASP3 protein, human|*Caspase 3|*Apoptosis|Pyroptosis|*Mitochondria|Signal Transduction|Cytochrome c|Cell Line, Tumor|Membrane, Mitochondrial|Receptors, Estrogen 79 DFNA5 30914761 Acta Pharmacol. Sin. 2019 PMC6786479 10.1038/s41401-019-0222-z 5 4 0 0 Humans|EEF2K protein, human|*Elongation Factor 2 Kinase|*Pyroptosis|*Doxorubicin|*Autophagy|Apoptosis|*Melanoma|siRNA|Cell Line, Tumor|Signal Transduction 79 DGCR2 30923314 NPJ Schizophr 2019 PMC6438978 10.1038/s41537-019-0073-0 0 2 0 182 Humans|MicroRNAs|RNA-Binding Proteins|*Psychosis|*Schizophrenia|Antipsychotic Agents|*Gene Expression|Disease Progression|Brain|Genotype|Single Nucleotide Polymorphisms|NDEL1 protein, human|Carrier Proteins 22 DGCR2 30901624 Psychiatry Res 2019 10.1016/j.psychres.2019.02.068 0 0 0 182 Humans|*Schizophrenia|Psychosis|Gyrus Cinguli|Antipsychotic Agents|Magnetic Resonance Imaging|Brain|Genetic Predisposition to Disease|Genotype 22 DGCR6 31875306 J. Neurooncol. 2019 10.1007/s11060-019-03377-8 1 0 0 67 Adult|Humans|Child|Child, Preschool|Aged|*Glioblastoma|Anaplastic Lymphoma Kinase|Brain Neoplasms|Receptor Protein-Tyrosine Kinases|Lung Neoplasms|Protein-Tyrosine Kinases|Mutation 24 DGCR6 30820038 Eur. J. Hum. Genet. 2019 PMC6777542 10.1038/s41431-019-0364-y 0 0 0 67 Humans|Bicuspid Aortic Valve|*DNA Copy Number Variations|*Heart Valve Diseases|*Aortic Valve|Thoracic Aortic Aneurysms|Congenital Heart Defect|Phenotype|Gene Expression Regulation|TBX20 protein, human|T-Box Domain Proteins 24 DHRS2 31528309 Gastroenterol Hepatol Bed Bench 2019 PMC6668765 2 0 0 173 Humans|*Computational Biology|caffeic acid|Gene Ontology|*Caffeic Acids|Profile, Gene Expression|Gene Expression Profiling|Gene Regulatory Networks|Protein Interaction Maps|Protein Interaction Mapping|Gene Expression Regulation, Neoplastic|*Genetic Screening|*Colon|*HT29 Cells 35 DHRS2 31436301 Oncol. Rep. 2019 PMC6775812 10.3892/or.2019.7291 0 0 0 173 Humans|*Oxaliplatin|HCT 116 Cells|Colorectal Cancer|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Antineoplastic Agents|Epithelial-Mesenchymal Transition|MicroRNAs|Cell Movement|Cell Line, Tumor|Signal Transduction|*Excision Repair|*Proteomics|Oxidoreductases 35 DHRS2 31423895 Epigenetics 2019 PMC6961673 10.1080/15592294.2019.1656155 0 0 0 173 Humans|Female|Inhibitors, HDAC|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Histone Deacetylases|Hydroxamic Acids|Vorinostat|Apoptosis|Cell Line, Tumor|Cell Survival|Prognosis 35 DHRS2 31380278 Front Oncol 2019 PMC6659439 10.3389/fonc.2019.00640 2 0 0 173 35 DHRS2 31291971 J. Exp. Clin. Cancer Res. 2019 PMC6617617 10.1186/s13046-019-1301-1 1 4 0 173 *Nasopharyngeal Carcinoma|trichothecin|*Trichothecenes|Cell Proliferation|*Growth Inhibitors|Nasopharyngeal Neoplasms|Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Cycle|Xenograft Model Antitumor Assays 35 DHX33 31632911 Front Oncol 2019 PMC6783507 10.3389/fonc.2019.00979 0 1 0 151 transcriptional intermediary factor 1|*Cancer|TRIM33 protein, human|*Transcription Factors|*Nuclear Proteins|SMAD2 protein, human|Smad2 Protein|SMAD4 protein, human|Smad4 Protein|Transforming Growth Factor beta|Signal Transduction|Cell Nucleus|Genes, Tumor Suppressor|E3 Ubiquitin Ligase|Phosphorylation|Promoter Regions, Genetic 25 DHX33 31182639 Mol. Cell. Biol. 2019 PMC6692123 10.1128/MCB.00017-19 1 6 0 151 Humans|DEAD-box RNA Helicases|Cell Proliferation|Apoptosis|Cell Line, Tumor|DHX33 protein, human 25 DHX33 31081075 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201904_17683 3 5 0 151 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|Apoptosis 25 DHX33 30684270 J. Cell. Physiol. 2019 10.1002/jcp.28178 0 0 0 151 Humans|DEAD-box RNA Helicases|Cell Proliferation|mRNA|Ribosome|Cell Line, Tumor|DHX33 protein, human 25 DIS3L2 31886366 Data Brief 2019 PMC6921154 10.1016/j.dib.2019.104943 0 0 0 76 Humans|*Nonsense Mediated mRNA Decay|HeLa Cells|mRNA|RNA Helicases|Codon, Nonsense|Exoribonucleases|Trans-Activators|DIS3L2 protein, human 76 DIS3L2 31762227 Am J Med Genet C Semin Med Genet 2019 10.1002/ajmg.c.31756 1 2 0 76 Male|Humans|Dogs|Animals|Pregnancy|*DNA Copy Number Variations|Genome-Wide Association Study|Phenotype|Abnormalities, Multiple|Chromosome Deletion|Growth Disorders|Pedigree|Mutation|Nuclear Proteins|Intracellular Signaling Peptides and Proteins|*Genes, X-Linked|CDKN1C protein, human|Cyclin-Dependent Kinase Inhibitor p57|Syndrome|NFIX protein, human|NFI Transcription Factors 76 DIS3L2 31466720 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.08.105 1 0 0 76 Humans|*Nonsense Mediated mRNA Decay|mRNA|Termination Codon, Premature|RNA Helicases|Exoribonucleases|Trans-Activators|DIS3L2 protein, human 76 DIS3L2 31368081 Endocrine 2019 10.1007/s12020-019-02009-5 0 0 0 76 Humans|*Thyroid Carcinoma, Anaplastic|*Biopsy, Fine-Needle|Thyroid Neoplasms|Proto-Oncogene Proteins B-raf|Prognosis|Mutation|High-Throughput Nucleotide Sequencing|*Cytodiagnosis|Cell Line 76 DIS3L2 31342438 Adv. Exp. Med. Biol. 2019 10.1007/978-3-030-19966-1_4 1 0 0 76 Humans|exoribonuclease II|Exoribonucleases|*mRNA Degradation|Exosome Multienzyme Ribonuclease Complex|RNA|Exosomes|RNA, Nuclear|Endoribonucleases|Subunits, Catalytic|DIS3 protein, human 76 DIS3L2 31331910 Cancer Res. 2019 10.1158/0008-5472.CAN-19-0376 3 1 0 76 Humans|*Carcinoma, Hepatocellular|*Heterogeneous-Nuclear Ribonucleoprotein U|*Liver Cancer|*Alternative Splicing|*Disease Progression|Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Tumorigenesis|RNA Splicing|RNA|Exon|DIS3L2 protein, human|Exoribonucleases 76 DIS3L2 31160785 Nat. Struct. Mol. Biol. 2019 PMC6554070 10.1038/s41594-019-0234-x 2 0 0 76 Mice|Animals|Pregnancy|Female|*RNA, Ribosomal|*Ribosomes|*Exonucleases|RNA, Ribosomal, 5.8S|Exoribonucleases|RNA Processing, Post-Transcriptional|RNA Precursors|RNA Stability|Cell Nucleus|Nephroblastomatosis, fetal ascites, macrosomia and Wilms tumor|Wilms Tumor|*Biochemical Phenomena|Fetal Macrosomia|Dis3l2 protein, mouse 76 DIS3L2 30770239 Mol. Cell 2019 PMC6430647 10.1016/j.molcel.2019.01.010 9 0 0 76 Humans|*miRNAs|*Tumor Suppressor Protein p53|Dyskeratosis Congenita|telomerase RNA|Telomerase|*Endoribonucleases|Exoribonucleases|*Ribonuclease, Pancreatic|RNA Nucleotidyltransferases|Telomere|Mutations 76 DIS3L2 30715470 Nucleic Acids Res. 2019 PMC6451125 10.1093/nar/gkz043 1 1 0 76 *Schizosaccharomyces|*RNA Decay|Schizosaccharomyces pombe Proteins|mRNA|Exoribonucleases|RNA|Nucleotidyltransferases|Uridine 76 DIS3L2 30687385 Front Genet 2019 PMC6334744 10.3389/fgene.2018.00699 4 0 0 76 Sheep|Animals|*Genome|Genotype|Phenotype|Sheep, Domestic|Breeding|Polymorphism, Single Nucleotide|Livestock|Ethiopia|Middle East|Africa, Southern|Europe|China|Caribbean 76 DIS3L2 30638126 RNA Biol 2019 PMC6380269 10.1080/15476286.2018.1564466 0 0 0 76 Female|Pregnancy|Humans|poly A specific exoribonuclease|*Exoribonucleases|*RNA Decay|Nephroblastomatosis, fetal ascites, macrosomia and Wilms tumor|Wilms Tumor|RNA, Micro|mRNA|Fetal Macrosomia|Protein Binding|Cytoplasm|*Cell Physiological Phenomena|DIS3L2 protein, human 76 DIS3L2 30613385 F1000Res 2019 PMC6305221 10.12688/f1000research.16203.1 1 0 0 76 *Transcription Factors|*mRNA Decay|RNA Caps|mRNA|*Gene Expression|Arabidopsis|RNA, Plant|*Biochemical Phenomena 76 DKKL1 31605445 Genes Brain Behav. 2019 10.1111/gbb.12614 1 1 0 98 Animals|Dogs|*Foxes|*Transcriptome|Hypothalamo-Hypophyseal System|Pituitary-Adrenal System|*Aggression|*Hypothalamus|Domestication|Behavior, Animal|Breeding|*Brain|Gene Modules|Russia 22 DLEC1 31547177 Cancers (Basel) 2019 PMC6826358 10.3390/cancers11101408 1 4 0 54 Humans|*Methylation|*Lung Cancer|Mediastinum|Carcinoma, Non-Small-Cell Lung|Bronchoscopy|Lymph Node|Endoscopic Ultrasound-Guided Fine Needle Aspiration|Neoplasm Staging|Lymphatic Metastasis|Endosonography|*Lymphadenopathy|*Image-Guided Biopsy|*Ultrasonography 69 DLEC1 31275357 Front Genet 2019 PMC6593391 10.3389/fgene.2019.00572 0 0 0 54 Humans|*Case-Control Studies|Genetic Association Studies|Phenotypes|Models, Genetic|Genetic Variation|*Research Design|Sizes, Sample|Computer Simulation 69 DLEC1 31241180 Int. J. Cancer 2019 10.1002/ijc.32532 1 0 0 54 Humans|*DNA Methylation|*Carcinoma, Non-Small-Cell Lung|*Squamous Cell Carcinoma|*Idiopathic Pulmonary Fibrosis|Lung Neoplasms|CpG Islands|Prognosis|Lung|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|DLEC1 protein, human|Tumor Suppressor Proteins 69 DLEC1 31176573 Pathol. Res. Pract. 2019 10.1016/j.prp.2019.152465 0 1 0 54 Humans|Female|*Myometrium|*Uterine Neoplasms|Leiomyomas|Leiomyosarcomas|*Genes, Tumor Suppressor|Sarcomas|Biomarkers, Tumor|DNA Methylation|Diagnosis, Differential|DLEC1 protein, human|Tumor Suppressor Proteins|ATF3 protein, human|Activating Transcription Factor 3 69 DLEC1 31130567 J Nippon Med Sch 2019 10.1272/jnms.JNMS.2019_86-201 0 0 0 54 *Lung Cancer|*DNA Methylation|Carcinoma, Non-Small-Cell Lung|Biomarkers, Tumor|Tumor Suppressor Proteins 69 DLEC1 30610381 Virchows Arch. 2019 10.1007/s00428-018-02511-7 1 0 0 54 Humans|*Intrahepatic Cholangiocarcinoma|*Bile Ducts, Intrahepatic|Bile Duct Neoplasms|CpG Island|DNA Methylation|Promoter Regions, Genetic|Prognosis|Biomarkers, Tumor|*Liver Neoplasms|DLEC1 protein, human|Tumor Suppressor Proteins 69 DLEC1 30607648 Cytotechnology 2019 PMC6368495 10.1007/s10616-018-0258-9 0 6 0 54 *Up-Regulation|CASP3 protein, human|Caspase 3|CASP9 protein, human|Caspase 9|bcl-X Protein|Caspases|Proto-Oncogene Proteins c-bcl-2|bcl-2-Associated X Protein|*Cell Death|Downregulation|Apoptosis|Fluorouracil|Cell Survival|Cell Line, Tumor|Curcumin|Cytochrome c|Mitochondria 69 DLL3 31819500 Onco Targets Ther 2019 PMC6877464 10.2147/OTT.S216362 1 3 0 191 Humans|*Small Cell Lung Carcinoma|CTLA4 protein, human|*CTLA-4 Antigen|*Prevalence|Lung Neoplasms|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Immunoconjugates|Biomarkers, Tumor|MSTN protein, human|Myostatin|DLL3 protein, human 224 DLL3 31817634 Cancers (Basel) 2019 PMC6966525 10.3390/cancers11121958 0 0 0 191 Humans|Mice|Animals|*Prognosis|Notch Receptors|*Leukemia, Myeloid, Acute|NOTCH2 protein, human|Receptor, Notch2|JAG2 protein, human|Jagged-2 Protein|*Signal Transduction|NOTCH3 protein, human|Receptor, Notch3|Receptor, Notch1|Ara-C|Biomarkers, Tumor|Kaplan-Meier Analysis|gamma-Secretase 224 DLL3 31678831 Lung Cancer 2019 10.1016/j.lungcan.2019.10.010 1 1 0 191 KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|NF-E2-Related Factor 2|*Carcinoma, Large Cell|*Carcinoma, Neuroendocrine|Lung Neoplasms|Small Cell Lung Carcinoma|Neuroendocrine Tumors|Mutations 224 DLL3 31590629 BMC Dev. Biol. 2019 PMC6781419 10.1186/s12861-019-0199-3 1 0 0 191 Mice|Animals|Receptor, Notch1|Fucose|Signal Transduction|Epidermal Growth Factor|Ligands|Membrane Proteins|Protein Binding|Mutation 224 DLL3 31508369 Front Oncol 2019 PMC6718711 10.3389/fonc.2019.00809 1 2 0 191 Humans|*Amyloid Precursor Protein Secretases|*Platelet Aggregation Inhibitors|*Growth Hormone-Secreting Pituitary Adenoma|*Signal Transduction|NOTCH2 protein, human|Receptor, Notch2|Receptors, Notch|*Tumorigenesis|*Cell Transformation, Neoplastic|Cell Proliferation|*Disease Progression|Growth Hormone 224 DLL3 31506387 Clin. Cancer Res. 2019 PMC7105795 10.1158/1078-0432.CCR-19-1133 14 0 0 191 Humans|rovalpituzumab tesirine|*Small Cell Lung Carcinoma|*Immunoconjugates|*Benzodiazepinones|*Antibodies, Monoclonal, Humanized|Lung Neoplasms|Intracellular Signaling Peptides and Proteins|Membrane Proteins|DLL3 protein, human 224 DLL3 31452726 Oncol Lett 2019 PMC6676644 10.3892/ol.2019.10538 2 2 0 191 Humans|Male|delta protein|*Prognosis|*Thyroid Gland|*Small Cell Lung Carcinoma|NKX2-1 protein, human|*Thyroid Transcription Factor 1|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Lung Neoplasms|rovalpituzumab tesirine|Benzodiazepinones|Immunoconjugates|Antibodies, Monoclonal, Humanized|Biomarkers, Tumor 224 DLL3 31447005 Lung Cancer 2019 10.1016/j.lungcan.2019.07.016 1 0 0 191 *Small Cell Lung Carcinoma|delta protein|Reproducibility of Results|Intracellular Signaling Peptides and Proteins|Membrane Proteins|*Lung Neoplasms|*Carcinoma, Neuroendocrine|*Carcinoid Tumor|rovalpituzumab tesirine|Benzodiazepinones|Immunoconjugates|Prognosis|Antibodies, Monoclonal, Humanized|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 224 DLL3 31447000 Lung Cancer 2019 10.1016/j.lungcan.2019.06.025 1 0 0 191 Humans|*Small Cell Lung Carcinoma|*Neoplastic Cells, Circulating|Lung Neoplasms|Biomarkers, Tumor|Vimentin|Cell Line, Tumor|Kaplan-Meier Estimate|DLL3 protein, human|Membrane Proteins|Intracellular Signaling Peptides and Proteins 224 Dlx1 31882504 In Vivo 2019 PMC6984119 10.21873/invivo.11786 0 0 0 168 Humans|Male|*Multiparametric Magnetic Resonance Imaging|Prostate|Prostate Cancer|Prostate-Specific Antigen|Digital Rectal Examination|Image-Guided Biopsy|Magnetic Resonance Imaging, Interventional|Ultrasonography, Interventional|Magnetic Resonance Imaging|Urinalysis 222 Dlx1 31783839 BMC Urol 2019 PMC6884880 10.1186/s12894-019-0561-6 0 0 0 168 Humans|Male|*Prostate Cancer|Prostate|Prostate-Specific Antigen|Neoplasm Grading|Digital Rectal Examination|Biopsy|Early Detection of Cancer|ROC Curve|Biomarkers, Tumor|*Urinary Tract|Risk Assessment 222 Dlx1 31762715 Dose Response 2019 PMC6851613 10.1177/1559325819886766 0 0 0 168 Animals|Mice|*RNA, Long Noncoding|*Messenger RNA|*Transcription Factors|*Stomach|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Downregulation|Upregulation|Gastric Mucosa|*Radiation Injury|Ionizing Radiation|*Stomach Diseases 222 Dlx1 31588660 J Magn Reson Imaging 2019 10.1002/jmri.26945 0 0 0 168 Humans|Male|*Prostate Cancer|*Magnetic Resonance Imaging|Prostate-Specific Antigen|Prostate|Image-Guided Biopsy|*Machine Learning|Risk Assessment 222 Dlx1 31433982 Cell Rep 2019 PMC6750766 10.1016/j.celrep.2019.07.022 2 9 0 168 Animals|Mice|*GABAergic Neurons|*Prosencephalon|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Enhancer Elements, Genetic|Genes, Homeobox|Interneurons|*Genomics|In Situ Hybridization|Cell Movement 222 Dlx1 31340933 Development 2019 10.1242/dev.175042 1 2 0 168 Humans|*Genes, Homeobox|Homeodomain Proteins|Body Patterning|Facial Bones|Gene Expression Regulation, Developmental|Transcription Factors|Histone Acetyltransferases|Embryo, Mammalian|*Gene Expression|Mutation 222 Dlx1 31298493 J. Cell. Mol. Med. 2019 PMC6714137 10.1111/jcmm.14402 4 11 0 168 Humans|Male|Mice|Animals|Mice, Nude|SMAD4 protein, human|*Smad4 Protein|*Downregulation|*Signal Transduction|*Prostate Cancer|miRNAs|Epithelial-Mesenchymal Transition|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|CDH1 protein, human|E Cadherin|Cell Line, Tumor|Up-Regulation|*Genes, Tumor Suppressor|Vimentin|Antigens, CD 222 Dlx1 31252405 J. Endocrinol. 2019 10.1530/JOE-19-0082 0 0 0 168 Female|Mice|Animals|Sexual Maturation|progonadoliberin I|*Gonadotropin Releasing Hormone|Hypothalamus|*Protein Precursors|T-box transcription factor TBX21|*T-Box Domain Proteins|Fertility|Reproduction|RNA, Messenger|Transcription Factors|miRNAs|Neurons|MIRN29 microRNA, mouse 222 Dlx1 31026217 J. Urol. 2019 10.1097/JU.0000000000000293 2 0 0 168 Humans|Male|*Prostate|*mRNA|*Prostate Cancer|Prostate-Specific Antigen|*Biopsy|Neoplasm Grading|Biomarkers, Tumor|*Urinalysis|Risk Assessment 222 Dlx1 30980391 J. Cell. Physiol. 2019 10.1002/jcp.28620 3 1 0 168 *RNA, Long Noncoding|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*Genes, Homeobox|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Tumorigenesis|Cell Line, Tumor|Apoptosis|Cell Transformation, Neoplastic 222 Dlx1 30859272 World J Urol 2019 10.1007/s00345-019-02719-5 3 0 0 168 222 DLX2 31825998 PLoS ONE 2019 PMC6905564 10.1371/journal.pone.0226212 0 0 0 403 Humans|*Genes, Homeobox|Homeodomain Proteins|Transcription Factors|*Myeloid Cells|Gene Expression Regulation, Leukemic|Leukemia, Myeloid, Acute|Cell Differentiation|Hematopoiesis|Lymphopoiesis|Myelodysplastic Syndrome|Myelopoiesis|Hematopoietic Stem Cells|Cell Line, Tumor|Gene Expressions 308 DLX2 31754327 Int. J. Biol. Sci. 2019 PMC6854364 10.7150/ijbs.35357 0 1 0 403 308 DLX2 31735399 Br J Oral Maxillofac Surg 2019 10.1016/j.bjoms.2019.10.311 0 0 0 403 Humans|Male|Female|Maxilla|Mandible|Cleft Palate|Face 308 DLX2 31529555 Oral Dis 2019 10.1111/odi.13196 0 0 0 403 Humans|Axenfeld-Rieger syndrome|*Eye Abnormalities|*Eye Diseases, Hereditary|*Anterior Eye Segment|Homeodomain Proteins|Transcription Factors|Mutations|Pedigree 308 DLX2 31464646 Stem Cell Res Ther 2019 PMC6714076 10.1186/s13287-019-1378-7 1 0 0 403 Humans|Mice|Animals|*Human Embryonic Stem Cells|BMP4 protein, human|*Bone Morphogenetic Protein 4|*Cell Differentiation|Odontogenesis|*Epithelium|MSX1 Transcription Factor|Tooth|Mouse Embryonic Stem Cells|Mesoderm|Signal Transduction 308 DLX2 31340933 Development 2019 10.1242/dev.175042 1 2 0 403 Humans|*Genes, Homeobox|Homeodomain Proteins|Body Patterning|Facial Bones|Gene Expression Regulation, Developmental|Transcription Factors|Histone Acetyltransferases|Embryo, Mammalian|*Gene Expression|Mutation 308 DLX2 31322179 Mol Med Rep 2019 10.3892/mmr.2019.10466 3 8 0 403 Humans|*MCF-7 Cells|*Reactive Oxygen Species|*Glycolysis|*Cell Signaling|*Mitochondria|Snail Family Transcription Factors|Distal-less homeobox proteins|Transcription Factors|Epithelial-Mesenchymal Transition|Homeodomain Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Oxidative Phosphorylation|Cytochrome c Oxidase 308 DMRTA2 31845734 Cereb. Cortex 2019 PMC7197206 10.1093/cercor/bhz310 0 0 0 12 Female|Pregnancy|Animals|Mice|Neurons|Neurogenesis|Cerebral Cortex|Cell Differentiation|Transcription Factors 25 DMRTA2 31799146 Biotechnol Rep (Amst) 2019 PMC6881697 10.1016/j.btre.2019.e00398 0 0 0 12 Animals|*Nile Tilapia|*Transcription Factor 3|Phylogeny|DMRT1 protein|Transcription Factors|*Genome|TCF3 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Synteny|Gene Expression Regulation, Developmental|Chromosomes 25 DMRTA2 31371378 Development 2019 10.1242/dev.174243 0 1 0 12 Animals|*Genes, Homeobox|*Cortices, Cerebral|Neurogenesis|Paired Box Transcription Factors|Homeodomain Proteins|Telencephalon|Neural Stem Cells|PAX6 Transcription Factor|Repressor Proteins|Eye Proteins|Gene Expression Regulation, Developmental|Neurons|3'-(1-butylphosphoryl)adenosine|(S-dinitrophenyl)-6-mercaptopurine riboside triphosphate|*Adenosine Triphosphate|*Thionucleosides 25 DMXL2 31688942 Brain 2019 10.1093/brain/awz326 1 2 0 56 Humans|Animals|Mice|Infantile Epileptic-Dyskinetic Encephalopathy|*Spasms, Infantile|Homozygote|Brain Diseases|Brain|Electroencephalography|MRI Scans|Sequencing, Whole Exome|Mutation|Siblings|Neurons|Phenotype|Codon, Nonsense|*Autophagy|DMXL2 protein, human|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing|DMXL2 protein, mouse 27 DMXL2 31253182 Mol Brain 2019 PMC6599304 10.1186/s13041-019-0483-y 1 1 0 56 Animals|Mice|voltage-dependent calcium channel (P-Q type)|Calcium Channels, N-Type|CAV2 protein, human|*Caveolin 2|Synaptic Vesicles|Neurons|Nerve Tissue Proteins 27 DMXL2 31118907 Front Psychiatry 2019 PMC6504680 10.3389/fpsyt.2019.00280 0 1 0 56 Humans|*Transcriptome|*Bipolar Disorder|Gene Expression Profiling|RNA, Long Noncoding|Sequencing, RNA|mRNA 27 DMXL2 31004036 J. Biol. Chem. 2019 PMC6579465 10.1074/jbc.RA119.007504 0 5 0 56 Rats|Animals|*Neuroendocrine Cells|Secretory Vesicles|Exocytosis|Calcium-Binding Proteins|Nerve Tissue Proteins|*Cryopyrin-Associated Periodic Syndromes|Biological Transport|PC12 Cells|Hydrogen-Ion Concentration 27 DMXL2 30735494 PLoS Genet. 2019 PMC6383954 10.1371/journal.pgen.1007909 1 5 0 56 Male|Female|Humans|Mice|Animals|Sexual Maturation|*Spermatogenesis|Sertoli Cells|Seminiferous Tubule|Testes|Sperm|Infertility, Male|Knockout Mouse|Fertility|Apoptosis|DMXL2 protein, human|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing|DMXL2 protein, mouse 27 DMXL2 30732576 J Neurodev Disord 2019 PMC6366120 10.1186/s11689-019-9263-3 1 0 0 56 *DNA Copy Number Variations|*Neurodevelopmental Disorders|Sequencing, Whole Genome|Gene Dosage|Phenotype|Mutation 27 DNAH9 31803243 Front Genet 2019 PMC6872681 10.3389/fgene.2019.01174 0 0 0 77 Dogs|Animals|Humans|*Polymorphism, Single Nucleotide|*Genome|Breeding|Linkage Disequilibrium|Genetics, Population|Selection, Genetic|Genetic Variation|Genotype|Homozygote|*Chinese|Genomics|China|Mongolia|Kazakhstan 40 DNAH9 31264768 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2019 10.1002/ajmg.b.32750 1 0 0 77 Child|Humans|Genome-Wide Association Study|*Chinese|*Dyslexia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Quantitative Trait Loci|Cohort Studies 40 DNAH9 31178125 Am. J. Hum. Genet. 2019 PMC6612517 10.1016/j.ajhg.2019.04.015 4 0 0 77 Male|Humans|*Asthenozoospermia|DNAH9 protein, human|Axonemal Dyneins|Axoneme|*Infertility, Male|Kartagener Syndrome|*Sperm|Cilia|Sperm Flagellum|*Mutations|Flagella|Phenotype|Pedigree|Proteins|Alleles|Tubulin 40 DNAH9 31119684 Genes Genomics 2019 10.1007/s13258-019-00820-y 1 0 0 77 Sheep|Animals|*Altitude|*Genome|*Genomics|Selection, Genetic|Genetics, Population|Adaptation, Physiological|Polymorphism, Single Nucleotide 40 DNAH9 31038188 Folia Neuropathol 2019 10.5114/fn.2019.83831 0 0 0 77 *Dynactin Complex|*Autopsy|*Dyneins|*Kinesin|*Traumatic Brain Injury|Forensic Pathology|Case-Control Studies|Brain|Biomarkers|*Biochemical Phenomena|Axons|Cytoskeleton 40 dnajc10 31276733 Biochimie 2019 10.1016/j.biochi.2019.06.018 0 11 0 331 Rats|Animals|*Periodontal Ligament|*Up-Regulation|*Stem Cells|Apoptosis|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Differentiation|Signal Transduction|Reactive Oxygen Species|*Protective Agents|Cell Proliferation|Oxidative Stress|Hydrogen Peroxide|*Transcriptional Activation|Cells, Cultured|Stem Cell Transplantation|Periodontium|lncRNA 32 dnajc10 31189758 Endocr. J. 2019 10.1507/endocrj.EJ18-0536 0 0 0 331 *Pituitary Neoplasms|*Adenoma|Growth Hormone-Secreting Pituitary Adenoma|*Pituitary Hormones, Anterior|Growth Hormone|CDK5 protein, human|*Cyclin-Dependent Kinase 5|Gene Expression Regulation, Neoplastic|RNA, Messenger|Cell Line, Tumor|*Drug Hypersensitivity 32 dnajc10 31120186 FEBS J. 2019 10.1111/febs.14936 2 0 0 331 Auxilin|*Parkinsonism|Clathrin|HSP40 Heat-Shock Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Mutations|Parkinson Disease|Protein Transport|Protein-Serine-Threonine Kinases 32 DNAJC14 31063128 Elife 2019 PMC6533061 10.7554/eLife.44187 3 2 0 65 Mice|Animals|Fibrolamellar hepatocellular carcinoma|*Carcinoma, Hepatocellular|Liver Cancer|*Oncogenesis|*Oncogenes|*Signal Transduction|HSP40 Heat-Shock Proteins|Cyclic AMP-Dependent Protein Kinase Catalytic Subunits|Heat Shock Protein 70|Gene Expression Regulation, Neoplastic 20 DNASE1L3 31794766 Clin. Chim. Acta 2019 10.1016/j.cca.2019.11.028 0 0 0 81 Humans|*Spondylitis, Ankylosing|*Biomarkers|Blood Sedimentation|*Serum|C-Reactive Protein|Severity of Illness Index|Enzyme-Linked Immunosorbent Assay|Deoxyribonucleases 67 DNASE1L3 31735730 J. Vet. Med. Sci. 2019 PMC6983664 10.1292/jvms.19-0499 0 0 0 81 *DNA Fragmentation|*Liver Diseases|Necrosis|*Cell Death|deoxyribonuclease B|*DNase|Hepatocytes|Acetaminophen|Chemical and Drug Induced Liver Injury|Liver|Endodeoxyribonucleases 67 DNASE1L3 31519860 J. Immunol. 2019 PMC6778307 10.4049/jimmunol.1800159 4 0 0 81 Humans|*Extracellular Traps|Vascular Endothelial Growth Factor A|*Macrophages|Neutrophils|*Leukocyte Count|Interleukin-1beta|Histones|DNA|Dendritic Cells 67 DNASE1L3 31518392 Hum. Mol. Genet. 2019 PMC6872433 10.1093/hmg/ddz183 0 0 0 81 *Parkinson Disease|Genome-Wide Association Study|alpha-Synuclein|*Genetic Testing|Ubiquitin-Protein Ligases|Genetic Predisposition to Disease|Mutation 67 DNASE1L3 31255286 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.06.069 1 0 0 81 Female|Pregnancy|Mice|Animals|caspase-activated deoxyribonuclease|*Cell Free DNA|*DNase|DFFB protein, human|*Poly-ADP-Ribose Binding Proteins|Necrosis|Apoptosis|Endodeoxyribonucleases|DNA Fragmentation|Hepatocytes|Deoxyribonuclease I|Liver|Acetaminophen|Dnase1l3 protein, mouse 67 DNASE1L3 31134708 Mol. Reprod. Dev. 2019 10.1002/mrd.23174 0 0 0 81 Cattle|Animals|Male|Humans|Percoll|*Proteomics|Serpin E2|*Spermatozoa|*Fertility|*Povidone|*Silicon Dioxide|Sperm Motility|Cryopreservation|Semen Preservation|Artificial Insemination|Centrifugation, Density Gradient|Semen|*Biomarkers|TSPAN8 protein, human|Tetraspanins|DPY19L2 protein, human|Membrane Proteins 67 DNASE1L3 31092713 J. Rheumatol. 2019 PMC6917988 10.3899/jrheum.181232 5 1 0 81 Humans|*Extracellular Traps|*Lupus Nephritis|*Lupus Erythematosus, Systemic|Autoantibodies|Neutrophils 67 DNASE1L3 31057555 Front Immunol 2019 PMC6478819 10.3389/fimmu.2019.00836 2 0 0 81 Mice|Animals|*Transcriptome|*RNA, Double-Stranded|Immunity, Innate|*ds-DNA|Signal Transduction|RNA, Viral|Cytosol|Fibroblasts 67 DNASE1L3 31022206 PLoS ONE 2019 PMC6483174 10.1371/journal.pone.0215479 1 0 0 81 Humans|*Autoimmunity|*DNA Copy Number Variations|*Genetic Heterogeneity|*Autoimmune Diseases|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Deoxyribonuclease I|Polymorphism, Restriction Fragment Length|deoxyribonuclease B|Deoxyribonucleases|Endodeoxyribonucleases|Lupus Erythematosus, Systemic 67 DNASE1L3 30775801 J. Cell. Biochem. 2019 10.1002/jcb.28441 3 0 0 81 Humans|*Carcinoma, Hepatocellular|*Liver Cancer|*Network, Gene|*Prognosis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Sequencing, RNA|Biomarkers, Tumor|Disease Progression|RNA|PHLDA1 protein, human|Transcription Factors 67 DNASE1L3 30707351 Hum. Genet. 2019 PMC6373277 10.1007/s00439-018-01966-7 3 0 0 81 Humans|Child|*Lupus Erythematosus, Systemic|Homozygote|Genetic Predisposition to Disease|Alleles|*Sequencing, Whole Genome|Polymorphism, Single Nucleotide|Heterozygote|Mutation|*Risk Factors 67 DNASE1L3 30682452 J. Allergy Clin. Immunol. 2019 10.1016/j.jaci.2018.12.1020 5 0 0 81 Humans|*Sputum|*Asthma|Eosinophils|Leukocyte Count|Biomarkers|Phenotypes|ROC Curve|Nitric Oxide|Inflammation 67 dnmt2 31864524 Pathology 2019 10.1016/j.pathol.2019.10.006 1 0 0 138 Humans|Male|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|*DNA Modification Methylases|*Epigenesis, Genetic|DNA Methylation|DNA (Cytosine-5-)-Methyltransferase 1|*Prostate|*Prostate Cancer|*Epigenetics|*Neoplastic Processes|*Disease Progression|DNA 178 dnmt2 31493391 J. Insect Physiol. 2019 10.1016/j.jinsphys.2019.103939 0 0 0 138 Animals|*Moths|Bacillus thuringiensis|Larvae|Hemolymph|*DNA Modification Methylases|Bombyx mori|Transcriptome|Insects|Gene Expression Profiling|Host-Pathogen Interactions|Immunity, Innate|5 Azacytidine|*Anti-Bacterial Agents|Serratia marcescens|DNA Methylation|Cell Proliferation|Peptides 178 dnmt2 31419316 New Phytol. 2019 PMC6916402 10.1111/nph.16125 0 0 0 138 *DNA Methylation|*Macrocystis|*Microalgae|*Epigenome|5 Methylcytosine|*Laminaria|*Plants|Genome|Cytosine|High-Throughput Nucleotide Sequencing|Gametophytes|Methyltransferases 178 dnmt2 31167695 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2019 0 0 0 138 Humans|Pregnancy|Female|*DNA Methylation|*B-DNA|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|DNA (Cytosine-5-)-Methyltransferase 1|*Abortion, Habitual|DNA-Binding Proteins|mRNA|Proto-Oncogene Proteins|TET1 protein, human|Mixed Function Oxygenases 178 dnmt2 31004819 Chemosphere 2019 10.1016/j.chemosphere.2019.04.076 1 1 0 138 *Arabidopsis|*DNA Methylation|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|*Metals, Rare Earth|*Endocytosis|Lanthanum|Leaves, Plant|ROS1 protein, Arabidopsis|Nuclear Proteins|Arabidopsis Proteins 178 dnmt2 30901604 Redox Biol 2019 PMC6429558 10.1016/j.redox.2019.101163 2 2 0 138 Child|Humans|*Medulloblastoma|*Telomere Homeostasis|Cerebellar Neoplasms|Proto-Oncogene Proteins c-myc|Genes, myc|*DNA Damage|Gene Expression Regulation, Neoplastic|Cell Proliferation|Upregulation|mRNA|Apoptosis|Cell Line, Tumor|*Oxidants|Actin Cytoskeleton|Actin Depolymerizing Factors 178 dnmt2 30715423 Nucleic Acids Res. 2019 PMC6468285 10.1093/nar/gkz063 3 0 0 138 Mice|Animals|*Micronutrient|queuine|*Eukaryotes|Queuosine|tRNAAsp|*Guanine|Anticodon|tRNA|Schizosaccharomyces pombe|*Trace Elements|Codon|Methylation|*Eubacteria|Guanosine|DNA (Cytosine-5-)-Methyltransferases 178 dnmt2 30704115 Genes (Basel) 2019 PMC6409601 10.3390/genes10020102 14 15 0 138 *Methyltransferases|*RNA|*5-Methylcytosine|*Eukaryotes|tRNA|Methylation|tRNA Methyltransferases|Mitochondrial RNA|RNA, Ribosomal|RNA Processing, Post-Transcriptional|mRNA|*Eukaryotic Cells|Cytoplasm|Mitochondria|Cell Nucleus|Gene Expression 178 DNTT 31762281 J. Org. Chem. 2019 10.1021/acs.joc.9b02585 0 0 0 417 Semiconductors|Thiophenes|Models, Molecular 56 DNTT 31677197 Genes Chromosomes Cancer 2019 10.1002/gcc.22821 0 0 0 417 *Leukemia, Prolymphocytic, T-Cell|*Transcriptome|*Whole Exome Sequencing|Chromosome Aberrations|Phenotype|Genes, T-Cell Receptor alpha|CD8-Positive T-Lymphocytes|T Cell Receptor 56 DNTT 31667285 Data Brief 2019 PMC6811884 10.1016/j.dib.2019.104522 0 0 0 417 diphenyl|*Vibrations|*Biphenyl Compounds|Surface Properties|Spectrum Analysis, Raman|Microscopy, Atomic Force 56 DNTT 31592413 Adv Sci (Weinh) 2019 PMC6774035 10.1002/advs.201900775 2 0 0 417 *Semiconductors|Transistors, Electronic|Thiophenes 56 DNTT 31459956 ACS Omega 2019 PMC6649087 10.1021/acsomega.9b00826 0 0 0 417 picene|*Chrysenes|Surface Properties|X-Ray Diffraction|*Films|Thiophenes 56 DNTT 31116897 Adv. Mater. Weinheim 2019 10.1002/adma.201808265 1 0 0 417 Transistors, Electronic|Nanotechnology|Equipment Design|Equipment Failure Analysis|Signal Processing, Computer-Assisted|Logic 56 DNTT 30781707 Materials (Basel) 2019 PMC6416593 10.3390/ma12040615 1 1 0 417 *Raman Spectroscopy|Transistors, Electronic|Semiconductor 56 DOC2A 31594980 Sci Rep 2019 PMC6783474 10.1038/s41598-019-50684-1 1 0 0 31 Synaptic Transmission|Synaptic Vesicles|Neurons|Action Potentials|Nerve Tissue Proteins|Hippocampus|Calcium|Membrane Fusion|Cells, Cultured 42 DOC2A 30844661 Epilepsy Res. 2019 10.1016/j.eplepsyres.2019.02.008 0 0 0 31 Animals|Rats|Humans|*Epilepsy, Temporal Lobe|Pilocarpine|Muscarinic Agonists|Intractable Epilepsy|Hippocampus|Glial Fibrillary Acidic Protein|Disease Models, Animal|Doc2a protein, rat|Calcium-Binding Proteins|Nerve Tissue Proteins 42 DOC2B 31594980 Sci Rep 2019 PMC6783474 10.1038/s41598-019-50684-1 1 0 0 90 Synaptic Transmission|Synaptic Vesicles|Neurons|Action Potentials|Nerve Tissue Proteins|Hippocampus|Calcium|Membrane Fusion|Cells, Cultured 55 DOC2B 31147445 J. Biol. Chem. 2019 PMC6635456 10.1074/jbc.RA119.007929 1 3 0 90 Rats|Animals|*Phosphatidylinositol|Synaptotagmin I|Synaptic Vesicles|Exocytosis|Membrane Fusion|Synaptic Transmission|Calcium-Binding Proteins|Neurons|Neurotransmitters|Nerve Tissue Proteins|Calcium|Cell Membrane|Protein Binding|PC12 Cells 55 DOC2B 30707251 Diabetologia 2019 PMC6451670 10.1007/s00125-019-4824-2 2 7 0 90 Mice|Animals|*Insulin Resistance|Diabetes Mellitus, Type 2|Insulin|*Muscle, Skeletal|Glucose|Biological Transport|Calcium-Binding Proteins|Homeostasis|Doc2b protein, mouse|Nerve Tissue Proteins 55 DPP10 31438481 Int J Mol Sci 2019 PMC6747096 10.3390/ijms20174073 0 0 0 67 Humans|Male|*Down-Regulation|Kv Channel-Interacting Proteins|Shal Potassium Channels|*Orchiectomy|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases 105 DPP10 30779416 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2019 10.1002/ajmg.b.32715 0 0 0 67 Humans|United States|*Bipolar Disorder|*Pedigree|Genetic Linkage|SNPs|Genetic Predisposition to Disease|Lod Score|Genotype|Genome-Wide Association Study|*Latino|Chromosome Mapping|Cohort Studies|Mexico|Costa Rica|Guatemala 105 DPP10 30638748 Int. J. Cardiol. 2019 10.1016/j.ijcard.2018.12.072 0 1 0 67 Animals|Cricetinae|Humans|Shal Potassium Channels|Kv Channel-Interacting Proteins|Ion Channel Gating|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Membrane Potentials|*Heart|Cell Membrane|Sodium|Arrhythmias, Cardiac|CHO Cells 105 DPP3 31849923 Front Microbiol 2019 PMC6902085 10.3389/fmicb.2019.02844 0 0 0 97 *Virulence|kalopanax saponin A|Candida albicans|Hyphae|*Saponins|*Oleanolic Acid|Antifungal Agents|Fungal Proteins|Biofilms|Virulence Factors|Microbial Sensitivity Tests|Cell Proliferation 39 DPP3 31639686 J Appl Lab Med 2019 10.1373/jalm.2018.027995 2 0 0 97 Humans|Critically Ill|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|DPP3 protein, human 39 DPP3 31558704 Cell Death Dis 2019 PMC6763424 10.1038/s41419-019-1960-z 2 2 0 97 Humans|Female|*Carcinoma, Hepatocellular|*Downregulation|*Liver Neoplasms|*Mothers|MicroRNAs|*Oncogene|Cell Proliferation|Carcinogenesis|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Hep G2 Cells|mRNA|Signal Transduction|G1 Phase|Disease Progression|Cell Cycle|SMAD3 protein, human|Smad3 Protein 39 DPP3 31472040 Eur. J. Heart Fail. 2019 10.1002/ejhf.1601 1 1 0 97 Humans|Mice|Animals|*Anti-Arrhythmia Agents|Dipeptidyl-Peptidase IV Inhibitors|Dipeptidyl Peptidase 4|*Hemodynamics|Heart Failure|*Peptidyl-Dipeptidase A|Cardiogenic Shock|Fibrosis 39 DPP3 31472039 Eur. J. Heart Fail. 2019 10.1002/ejhf.1600 1 0 0 97 Mice|Animals|*Shock, Cardiogenic|Intra-Aortic Balloon Pumping|*Hemodynamics|Myocardial Infarction|Heart Failure|*Peptidyl-Dipeptidase A|Biomarkers|Cohort Studies 39 DPP3 31390378 PLoS ONE 2019 PMC6685676 10.1371/journal.pone.0220866 0 0 0 97 Animals|Humans|DPP3 protein, human|*Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Aminopeptidases|Ion Exchange Chromatography|Dipeptidyl Peptidase 4|Chromatography, Gel|Electrophoresis, Polyacrylamide Gel|Kidney|Amino Acid Sequence|Endopeptidases|Antibodies, Monoclonal 39 DPP3 31295380 J. Bone Miner. Res. 2019 PMC7203631 10.1002/jbmr.3829 0 0 0 97 Humans|Female|Mice|Animals|KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|NF-E2-Related Factor 2|*Oxidative Stress|Osteoclasts|*Bone Diseases, Metabolic|Osteoblast|Apoptosis|Antioxidants|Bone|Mice, Knockout|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases 39 DPP3 31176484 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.05.165 2 0 0 97 *Candida albicans|*Farnesol|*Virulence|cinnamic aldehyde|Candidiasis|Hyphae|*Acrolein|Antifungal Agents|Biofilms|Fungal Proteins|Virulence Factors 39 DPP3 30876764 Neurotoxicology 2019 10.1016/j.neuro.2019.03.003 0 4 0 97 Rats|Animals|KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Quinolinic Acid|*Oxidative Stress|*Corpus Striatum|*Neostriatum|Sequestosome-1 Protein|*GA-Binding Protein Transcription Factor|Antioxidants|*Gene Expression Regulation|Signal Transduction|Reactive Oxygen Species|Oxidation-Reduction|Neurons 39 DPP6 31873789 Diabetologia 2019 10.1007/s00125-019-05068-5 2 0 0 127 Humans|Mice|Animals|*Dipeptidyl Peptidase A|Tomography, X-Ray Computed|*Insulin-Secreting Cells|Pancreatic Islet|Insulin Secretion|Insulin|Glucose|Cell Line|*Cell Nucleus 146 DPP6 31832114 EPMA J 2019 PMC6882982 10.1007/s13167-019-00187-w 1 0 0 127 Humans|*Pituitary Neoplasms|*Proteomics|*Follicle Stimulating Hormone|*Prognosis|Adenoma 146 DPP6 31775073 J. Neuroimmunol. 2019 10.1016/j.jneuroim.2019.577114 0 0 0 127 Male|*Sleep Initiation and Maintenance Disorders|Hashimoto's encephalitis|*Encephalitis|Hashimoto Disease|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|*Dementia|Potassium Channels|Nerve Tissue Proteins|*Peptidyl-Dipeptidase A|Brain|Autoantibodies 146 DPP6 31532792 PLoS ONE 2019 PMC6750571 10.1371/journal.pone.0221957 2 0 0 127 Humans|APOL1 protein, human|*Apolipoprotein L1|*Blood Pressure|*Alleles|*Hypertension|Angiotensin II Type 1 Receptor Blockers|Tetrazoles|Antihypertensives|*Hypotension|African Americans|Benzimidazoles|proto-oncogene proteins c-mas-1|*Receptors, G-Protein-Coupled|*Proto-Oncogene Proteins|Angiotensins 146 DPP6 31476289 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111561 0 0 0 127 Humans|Paroxysmal ventricular fibrillation|Ventricular Fibrillation|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Shal Potassium Channels|Sudden Cardiac Arrest|*Chinese|Nerve Tissue Proteins|HEK293 Cells|DPP6 protein, human|Potassium Channels 146 DPP6 31475484 Mol Genet Genomic Med 2019 PMC6785528 10.1002/mgg3.954 1 0 0 127 Humans|*Siblings|*Intellectual Disability|*Mosaicism|*Phenotypes|DNA Copy Number Variations|Gene Duplication 146 DPP6 31438481 Int J Mol Sci 2019 PMC6747096 10.3390/ijms20174073 0 0 0 127 Humans|Male|*Down-Regulation|Kv Channel-Interacting Proteins|Shal Potassium Channels|*Orchiectomy|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases 146 DPP6 31212013 Mol. Cell. Neurosci. 2019 PMC6639039 10.1016/j.mcn.2019.06.007 0 0 0 127 *Bungarotoxins|Shal Potassium Channels|Kv Channel-Interacting Proteins|*Protein Transport|*Binding Site|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Neurons|*Protein Domains|Cells, Cultured|*Cell Movement 146 DPP6 31164693 Sci Rep 2019 PMC6547746 10.1038/s41598-019-44765-4 3 4 0 127 Humans|Aged|*Twins, Monozygotic|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Neurodegenerative Diseases|Australia|DNA Methylation|Epigenesis, Genetic|Epigenetic|Phenotype|*Gene Expression|Whole Exome Sequencing|Cohort Studies|C9orf72 protein, human|C9orf72 Protein 146 DPP6 31123420 Cancer Manag Res 2019 PMC6510395 10.2147/CMAR.S202394 1 0 0 127 146 DPP6 31114860 Europace 2019 10.1093/europace/euz151 0 0 0 127 Humans|Paroxysmal ventricular fibrillation|*Defibrillators, Implantable|*Incidence|*Ventricular Fibrillation|Sudden Cardiac Arrest|Tachycardia, Ventricular|Electrocardiography|Follow-Up Studies|Risk Factors 146 DPP6 31099194 J. 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Sci. 2019 PMC6522894 10.3346/jkms.2019.34.e144 0 1 0 127 *Carcinoma, Renal Cell|*Progression-Free Survival|Kidney Neoplasms|DNA Methylation|CpG Islands|Epigenesis, Genetic|Prognosis|Promoter Regions, Genetic|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 146 DPP6 30874922 Acta Neuropathol. 2019 PMC6531610 10.1007/s00401-019-01976-3 4 1 0 127 Humans|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Shal Potassium Channels|Nerve Tissue Proteins|Neurons|Brain|*Nervous System Physiological Phenomena|Haplotype|Dementia|DPP6 protein, human|Potassium Channels 146 DPP6 30849121 PLoS ONE 2019 PMC6407777 10.1371/journal.pone.0213299 2 3 0 127 Mice|Animals|*Glucagon-Secreting Cells|*Diet, High-Fat|*Transcriptome|Diabetes Mellitus, Experimental|*Insulin-Secreting Cells|Islets of Langerhans|Glucagon|Mice, Hyperglycemic|Insulin|Obesity|Transgenic Mouse|Exocytosis|Mice, Inbred C57BL 146 DPP9 31792328 Sci Rep 2019 PMC6889119 10.1038/s41598-019-54695-w 0 3 0 173 Humans|Mice|Animals|*Multiple Myeloma|Dipeptidyl Peptidases|Dipeptidyl Peptidase 4|Dipeptidases|Dipeptidyl-Peptidase IV Inhibitors|saxagliptin|Adamantane|Vildagliptin|Dipeptides|Cell Lines|Apoptosis|DPP8 protein, human 129 DPP9 31525884 ACS Chem. Biol. 2019 PMC6862324 10.1021/acschembio.9b00462 0 14 0 173 Humans|*Inflammasomes|CARD Signaling Adaptor Proteins|Apoptosis Regulatory Proteins|Dipeptidyl Peptidases|Adaptor Proteins, Signal Transducing|HEK293 Cells|DPP9 protein, human|CARD8 protein, human|Neoplasm Proteins 129 DPP9 31417085 Nat Commun 2019 PMC6695498 10.1038/s41467-019-11549-3 4 1 0 173 Humans|*Ubiquitin|*SUMO-1 Protein|Sumoylation|Small Ubiquitin-Related Modifier Proteins|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Proteolysis|Ubiquitin-Protein Ligases|Nuclear Proteins|Intranuclear Inclusion Bodies|SUMO2 protein, human|RNF4 protein, human|Transcription Factors|SUMO1 protein, human|RNF111 protein, human|ULS1 protein, S cerevisiae|DNA Helicases 129 DPP9 31383852 Cell Death Dis 2019 PMC6683174 10.1038/s41419-019-1817-5 3 7 0 173 Humans|Mice|Animals|*Alleles|Pyroptosis|Caspase 1|Inflammasomes|CARD Signaling Adaptor Proteins|Apoptosis Regulatory Proteins|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Adaptor Proteins, Signal Transducing|Antigens, Bacterial|Macrophages|HEK293 Cells|Cell Death|Flagellin|Boronic Acids|NLRP1 protein, human|CARD8 protein, human|Neoplasm Proteins|DPP8 protein, human 129 DPP9 31339356 Am. 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Ther. 2019 10.1016/j.pharmthera.2019.02.015 6 0 0 173 Humans|DPP4 protein, human|*Dipeptidyl Peptidase 4|Dipeptidyl-Peptidase IV Inhibitors|Mesothelioma, Malignant|Lung Neoplasms|Chemokines|Biomarkers, Tumor|Mesothelioma 129 DPP9 30718379 Life Sci Alliance 2019 PMC6362307 10.26508/lsa.201900313 5 7 0 173 Humans|Mice|Animals|*Inflammasomes|Leukocytes, Mononuclear|Pyroptosis|*Macrophages|Caspase 1|CARD Signaling Adaptor Proteins|Apoptosis Regulatory Proteins|Dipeptidyl Peptidases|Proteolysis|Mice, Inbred C57BL|HEK293 Cells|DPP9 protein, human|CARD8 protein, human|Neoplasm Proteins|DPP8 protein, human|Dipeptidases 129 DPPA2 31627455 Int J Mol Sci 2019 PMC6829864 10.3390/ijms20205156 0 3 0 42 *Ligands|Pseudomonas aeruginosa|Bacterial Proteins|Chemotaxis|ATP-Binding Cassette Transporters|Substrate Specificity|Bacteria 62 DPPA2 31226106 PLoS Biol. 2019 PMC6608977 10.1371/journal.pbio.3000324 6 3 0 42 Mice|Animals|*E3 Ligase|*Zygotes|Protein Inhibitors of Activated STAT|Transcription Factors|Sumoylation|Nuclear Proteins|DNA-Binding Proteins|SUMO-1 Protein|Poly-ADP-Ribose Binding Proteins|Embryo Development|Transcriptional Activation|Genome|Mouse Embryonic Stem Cells|Embryonic Stem Cells|Cell Line 62 DPPA2 30948459 EMBO Rep. 2019 PMC6500978 10.15252/embr.201847382 12 0 0 42 Mice|Animals|*Mouse Embryonic Stem Cells|Zygotes|Embryonic Development|Genome|Homeodomain Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Embryonic Stem Cells|Oocyte|Chromatin 62 DPPA2 30758381 Biomater Sci 2019 10.1039/c9bm00039a 0 0 0 42 Humans|Cricetinae|Animals|*Polyethyleneimine|*Molecular Weight|*Zinc|*Transfection|Gene Delivery Systems|polycations|Polyamines|DNA|Plasmids|Cricetulus|CHO Cells|Particle Size|HeLa Cells|2,2'-dipicolylamine|Picolinic Acids|Cell Survival 62 DPPA2 30692203 Genes Dev. 2019 PMC6362816 10.1101/gad.321174.118 16 0 0 42 Mice|Animals|*Zygotes|Transcription Factor|Embryonic Development|Mouse Embryonic Stem Cells|Genome|Homeodomain Proteins|Embryonic Stem Cells|Gene Expression Regulation, Developmental|Embryo, Mammalian|Nuclear Proteins|Chromatin Immunoprecipitation|Germ Line|Gene Activation|Promoter Regions, Genetic 62 DRAM1 31776983 Adv. Exp. Med. Biol. 2019 10.1007/978-981-15-0602-4_6 0 9 0 255 TP53 protein, human|*Tumor Suppressor Protein p53|*TP53 Genes|*Autophagy|Apoptosis Regulatory Proteins|Apoptosis|Beclin 1|Membrane Proteins|Cell Line, Tumor|Homeostasis|Signal Transduction|Gene Expression Regulation|Transcription Factor|DNA Damage 94 DRAM1 31719630 Sci Rep 2019 PMC6851103 10.1038/s41598-019-53247-6 0 4 0 255 Humans|Rats|Animals|*VEGF-B|*Tumor Suppressor Protein p53|*Vascular Endothelial Growth Factor A|*Autophagy|*Lung|Particulate Matter|Epithelial Cells|Signal Transduction|Bronchi|Air Pollutants|STAT3 protein, human|STAT3 Transcription Factor|Upregulation|Transcriptional Activation|Inflammation 94 DRAM1 31636666 J Oncol 2019 PMC6766143 10.1155/2019/5613417 1 1 0 255 Humans|*Drug Resistance, Neoplasm|*Autophagy|*Leukemia, Myeloid, Acute|3' UTR|MicroRNAs|Downregulation|Signal Transduction|Apoptosis|siRNA|Adriamycin 94 DRAM1 31598806 Biogerontology 2019 PMC6942598 10.1007/s10522-019-09841-2 1 1 0 255 Mice|Animals|TP53 protein, human|*Tumor Suppressor Protein p53|*Interleukin-6|*Mice, Inbred C57BL|MDM2 protein, human|Mdm2 Protein|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|bcl-2-Associated X Protein|Apoptosis|*Hippocampus|Cyclin-Dependent Kinase Inhibitor p21|Cell Survival|Memory|Gene Expression Regulation|Signal Transduction 94 DRAM1 31492633 Mol. Cell 2019 PMC6892261 10.1016/j.molcel.2019.07.021 1 3 0 255 Humans|*mTORC1|*Lysosomes|Amino Acid Transport System ASC|Signal Transduction|Autophagy|Amino Acids|Cell Proliferation|Biological Transport|HeLa Cells|Minor Histocompatibility Antigens|Glutamine|Cell Cycle|HEK293 Cells|SLC1A5 protein, human|SCAMP3 protein, human|Carrier Proteins|Membrane Proteins 94 DRAM1 31491460 Cell. Signal. 2019 10.1016/j.cellsig.2019.109411 0 3 0 255 Humans|*Sirtuin 1|*MCF-7 Cells|*AMP-Activated Protein Kinases|*Nitrosative Stress|*Autophagy|Cell Survival|Tumor Suppressor Protein p53|Apoptosis|Microtubule-Associated Proteins|Oxidative Stress|Membrane Potential, Mitochondrial|SIRT1 protein, human 94 DRAM1 31428131 Front Genet 2019 PMC6690020 10.3389/fgene.2019.00694 0 0 0 255 Animals|*DNA Methylation|hydrogen sulfite|*Macaca fascicularis|Epigenesis, Genetic|*RNA-Seq|*Sulfites|CpG Islands|*Sequencing, Whole Genome|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|*Whole Exome Sequencing|Promoter Regions, Genetic|Software|Gene Expression Regulation|*Gene Expression|*Biochemical Phenomena|*Brain 94 DRAM1 31356858 Cell. Signal. 2019 10.1016/j.cellsig.2019.109375 0 0 0 255 Humans|*Golgi Apparatus|Lysosome|Protein Transport|Syntaxin 6|Autophagy|Biological Transport|Plasma Membrane|HeLa Cells 94 DRAM1 31323026 PLoS ONE 2019 PMC6641656 10.1371/journal.pone.0219363 2 4 0 255 Humans|*Cisplatin|*Tumor Suppressor Protein p53|*Weightlessness|*Apoptosis|CASP3 protein, human|Caspase 3|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|bcl-2-Associated X Protein|Signal Transduction|PTEN protein, human|PTEN Phosphohydrolase|*Microgravity Simulation|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic 94 DRAM1 31160616 Sci Rep 2019 PMC6546785 10.1038/s41598-019-44535-2 1 0 0 255 Humans|*Diabetes Mellitus, Type 2|*Precursor Muscle Cells|*Autophagy|Myogenesis|Cell Differentiation|Apoptosis|Sequencing, RNA|Cells, Cultured 94 DRAM1 30990357 Autophagy 2019 PMC6984605 10.1080/15548627.2019.1607694 2 0 0 255 Phosphatidylinositol 3-Kinases|Autophagy|*Cell Differentiation|Apoptosis Regulatory Proteins|*Embryonal Carcinoma Cells|Apoptosis|Endoplasmic Reticulum Stress|Signal Transduction|Lysosomes|Cell Survival|Reactive Oxygen Species|*B-Lymphocytes|Unfolded Protein Response|Proteasome|*Quality Control 94 DRAM1 30902093 Cell Commun. Signal 2019 PMC6431019 10.1186/s12964-019-0341-7 0 78 0 255 *Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Ribosomal Protein S6|MTOR protein, human|*TOR Serine-Threonine Kinases|*Cell Proliferation|*Autophagy|Signal Transduction|Apoptosis|Receptor, IGF Type 1|Phosphorylation|Cell Line, Tumor|Insulin-Like Growth Factor I|RNA, Small Interfering|ribosomal protein S6 kinase, 90kDa, polypeptide 3|*Ribosomal Protein S6 Kinases, 90-kDa|RNA, Messenger 94 DRAM1 30755075 Autophagy 2019 PMC6526813 10.1080/15548627.2019.1580512 5 3 0 255 Humans|Mice|Animals|*Lupus Nephritis|*Podocytes|Leukocytes, Mononuclear|Genome-Wide Association Study|*Autophagy|MAP1LC3B protein, human|Microtubule-Associated Proteins|Lupus Erythematosus, Systemic|Autophagy-Related Protein 5|Kidney|Phagocytosis|NPHS2 protein|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Reactive Oxygen Species|APOL1 protein, human|Apolipoprotein L1|CLEC16A protein, human 94 DRAM2 31394102 Exp. Eye Res. 2019 10.1016/j.exer.2019.107752 1 0 0 31 Adult|Humans|*Cone-Rod Dystrophies|*Homozygote|Electroretinography|Cone-Rod Dystrophy 3|Retinitis Pigmentosa|*Phenotype|Visual Acuity|Retinal Dystrophies|Coherence Tomography, Optical|Photoreceptors, Cone|Retina|Pedigree|Visual Fields|Sequencing, Whole Exome|Fundus Oculi|Mutation|Mutations, Frameshift|DRAM2 protein, human 21 DRAM2 30755245 J. Exp. Clin. Cancer Res. 2019 PMC6373025 10.1186/s13046-019-1068-4 1 13 0 31 Humans|*Carcinoma, Non-Small-Cell Lung|*Tumor Suppressor Protein p53|*Lung Neoplasms|*Oncogene|Oncogenesis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|Lymphatic Metastasis|Down-Regulation|DRAM2 protein, human|Membrane Proteins 21 DRP2 31562664 Plant J. 2019 10.1111/tpj.14549 0 1 0 48 Animals|*RNA, Plant|Turnip mosaic virus|Potyvirus|Arabidopsis thaliana|Arabidopsis Proteins|Viral Proteins|Tobacco|Plant Diseases|Host-Pathogen Interactions|Plants, Genetically Modified|Plant Leaves|Virus Replication|Endocytosis|Infections 49 DRP2 31217940 Iran J Basic Med Sci 2019 PMC6556509 10.22038/ijbms.2019.30754.7414 0 0 0 48 *Whole Exome Sequencing|*Utrophin|Charcot Marie Tooth Disease|dystrophin-related protein 2|*Cytoskeletal Proteins|*Muscle Proteins|*Membrane Proteins|Exome|Pedigree|Mutation|Exons|Phenotype 49 DRP2 31182966 Cell. Mol. Biol. Lett. 2019 PMC6554968 10.1186/s11658-019-0162-0 10 1 0 48 Humans|*Transcriptome Profiling|Bioinformatics|Gene Ontology|Protein Interaction Maps|Transcriptome|Gene Regulatory Networks|Protein Interaction Mapping|Gene Expression Regulation, Neoplastic|Databases, Genetic|Biomarkers, Tumor|Signal Transduction 49 DUOXA2 31824516 Front Immunol 2019 PMC6883716 10.3389/fimmu.2019.02750 1 1 0 41 Mice|Animals|*Th17 Cells|*Flagellin|*Intestines|IL17A protein, human|Interleukin-17|Intestinal Mucosa|Intestine, Small|Flora, Intestinal|Bacteria|Cell Differentiation|*Clostridiaceae 99 DUOXA2 31751626 Mol. Cell. Endocrinol. 2019 10.1016/j.mce.2019.110638 2 0 0 41 Humans|Child|*Congenital Hypothyroidism|DUOX1|Iodide Peroxidase|Thyroid Hormones|Goiter|Receptors, Thyrotropin|Mutations|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Gland, Thyroid|Genes, Homeobox|Phenotype|*Folding, Protein|FOXE1 protein, human|Forkhead Transcription Factors|DUOX2 protein, human|DUOXA2 protein, human|Membrane Proteins 99 DUOXA2 31678421 Mol. Cell. Endocrinol. 2019 10.1016/j.mce.2019.110635 0 0 0 41 *Thyroid Gland|DUOX1|Oxidases, NADPH|Thyroid Hormones|Hypothyroidism|Membrane Proteins|Hydrogen Peroxide|Phenotypes 99 DUOXA2 31650902 Thyroid 2019 PMC6983755 10.1089/thy.2019.0182 0 2 0 41 99 DUOXA2 31548328 J. Immunol. 2019 PMC6804760 10.4049/jimmunol.1800469 0 7 0 41 Humans|*Dual Oxidases|*Hydrogen Peroxide|IL17A protein, human|*Interleukin-17|*Interleukin-4|*Up-Regulation|*Pancreatic Cancer|*Peroxides|NADPH Oxidases|*Colon|*Pancreas|*DNA Damage|*Oxidation-Reduction|*Transcriptional Activation|Reactive Oxygen Species|Membrane Proteins|Cell Line, Tumor|Oxidative Stress 99 DUOXA2 31513783 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111620 0 2 0 41 Humans|*Dual Oxidases|*Oxidase|NADPH Oxidases|Membrane Proteins|Cell Membrane|Reactive Oxygen Species|Hydrogen Peroxide|Thyroid Hormones|*Multienzyme Complexes|HEK293 Cells|Thyroid Gland|DUOX2 protein, human|DUOXA2 protein, human 99 DUOXA2 31428054 Front Endocrinol (Lausanne) 2019 PMC6688124 10.3389/fendo.2019.00526 1 0 0 41 99 DUOXA2 31301652 Folia Med (Plovdiv) 2019 10.2478/folmed-2018-0078 0 0 0 41 *Thyroid Gland|*Thyroid Diseases|Receptors, Thyrotropin|Graves Disease|Thyroid Neoplasms|Genetic Predisposition to Disease 99 DUOXA2 31172499 Methods Mol. Biol. 2019 10.1007/978-1-4939-9424-3_37 2 0 0 41 *Congenital Hypothyroidism|Dual Oxidases|Thyroid Hormones|Oxidases, NADPH|Gland, Thyroid|Membrane Proteins|Mutations|Hydrogen Peroxide|Alleles 99 DUOXA2 31172473 Methods Mol. Biol. 2019 10.1007/978-1-4939-9424-3_11 0 1 0 41 Humans|Dual Oxidases|Oxidases, NADPH|Congenital Hypothyroidism|Membrane Proteins|Cell Membrane|Hydrogen Peroxide|HEK293 Cells|Mutations, Missense|DUOX2 protein, human|DUOXA2 protein, human 99 DUOXA2 31044655 Thyroid 2019 PMC6588112 10.1089/thy.2018.0587 0 1 0 41 99 DUOXA2 30867238 J. Immunol. 2019 10.4049/jimmunol.1800443 2 11 0 41 Mice|Animals|*NADPH Oxidase|*Reactive Oxygen Species|Phosphatidylinositol 3-Kinases|*Signal Transduction|*Lymphocyte Activation|*Cell Proliferation|B Cells|Second Messenger|*Oxidation-Reduction|Cell Line|Receptors, Antigen, B-Cell 99 DUSP22 31882178 Semin Diagn Pathol 2019 10.1053/j.semdp.2019.12.002 0 0 0 208 *Lymphoma, Large-Cell, Anaplastic|DUSP22 protein, human|Mitogen-Activated Protein Kinase Phosphatases|Anaplastic Lymphoma Kinase|T-Cell Lymphomas, Peripheral|Receptor Protein-Tyrosine Kinases|Lymphoma, Primary Cutaneous Anaplastic Large Cell|Dual-Specificity Phosphatases|Breast Implant|Prognosis|Lymphoma, Large B-Cell, Diffuse|interferon regulatory factor-4|Interferon Regulatory Factors|Skin Neoplasms 86 DUSP22 31809310 Appl. Immunohistochem. Mol. Morphol. 2019 10.1097/PAI.0000000000000798 0 0 0 208 Humans|*Lymphoma, Large-Cell, Anaplastic|CD274 protein, human|*B7-H1 Antigen|*Tumor Microenvironment|Anaplastic Lymphoma Kinase|*T-Lymphocytes, Cytotoxic|Lymphocytes, Tumor-Infiltrating|Receptor Protein-Tyrosine Kinases|Prognosis|Lymphoma, Large B-Cell, Diffuse 86 DUSP22 31766293 Cells 2019 PMC6912701 10.3390/cells8111433 1 0 0 208 Humans|*T Cells|DUSP4 protein, human|Mitogen-Activated Protein Kinase Phosphatases|DUSP10 protein, human|DUSP5 protein, human|*Phosphatases, DUSP|DUSP22 protein, human|*Lupus Erythematosus, Systemic|hematopoietic progenitor kinase 1|Protein-Serine-Threonine Kinases|*Signal Transduction|MAP4K3 protein, human|Autoimmune Responses|Autoimmune Diseases|Lymphocyte Activation|MAP Kinase Kinase Kinases|DUSP7 protein, human|DUSP14 protein, human 86 DUSP22 31706671 Pathology 2019 10.1016/j.pathol.2019.09.007 0 0 0 208 Humans|*Lymphoma, Large-Cell, Anaplastic|ALK protein, human|Anaplastic Lymphoma Kinase|DUSP22 protein, human|Mitogen-Activated Protein Kinase Phosphatases|Dual-Specificity Phosphatases|Rearrangements, Gene|Receptor Protein-Tyrosine Kinases|Lymphoma, Primary Cutaneous Anaplastic Large Cell|TP63 protein, human|Tumor Suppressor Proteins|Ki-1 Antigen|Transcription Factors|Breast Implant|Prognosis|In Situ Hybridization, Fluorescence|Skin Neoplasms 86 DUSP22 31693867 FASEB J. 2019 10.1096/fj.201802558RR 2 10 0 208 Humans|Male|AR protein, human|*Androgen Receptor|DUSP22 protein, human|*Mitogen-Activated Protein Kinase Phosphatases|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|*Dual-Specificity Phosphatases|EGFR protein, human|*Epidermal Growth Factor Receptor|kallikrein-related peptidase 3, human|Prostate Specific Antigen|*Prostate Cancer|Phosphorylation|Signal Transduction|Mitogen-Activated Protein Kinase 1|Cellular Proliferation|MAP Kinase Signaling System|Kallikreins 86 DUSP22 31594044 Zhonghua Bing Li Xue Za Zhi 2019 10.3760/cma.j.issn.0529-5807.2019.10.008 0 0 0 208 86 DUSP22 31594013 Dtsch. Med. Wochenschr. 2019 10.1055/a-0597-7606 0 0 0 208 *Lymphoma, T-Cell, Peripheral|Immunoblastic Lymphadenopathy|Anaplastic Large Cell Lymphoma|Immunoconjugates|Sequencing, Next-Generation|Prognosis|Mutations 86 DUSP22 31570354 BMJ Case Rep 2019 10.1136/bcr-2019-230641 0 1 0 208 Humans|Mitogen-Activated Protein Kinase Phosphatases|Anaplastic Large Cell Lymphoma|Dual-Specificity Phosphatases|Anaplastic Lymphoma Kinase|Receptor Protein-Tyrosine Kinases|Gene Rearrangement|Biomarkers, Tumor 86 DUSP22 31488561 Haematologica 2019 PMC7271600 10.3324/haematol.2019.226647 2 0 0 208 *Lymphoma, T-Cell, Peripheral|T Cell Lymphoma|*Gene Expression Profiling|Epstein Barr Virus|Killer Cells, Natural|*Microarray Analysis|Biomarkers, Tumor|T-Lymphocytes 86 DUSP22 31278738 Am. J. Clin. Pathol. 2019 10.1093/ajcp/aqz078 0 0 0 208 *Lymphoma|Lymphoma, B-Cell|Gene Rearrangement 86 DUSP22 31206807 J. Clin. Lab. Anal. 2019 PMC6757113 10.1002/jcla.22945 1 0 0 208 Humans|*Down-Regulation|*Sepsis|*Inflammation|APACHE|Cytokines|*Disease Susceptibility|RNA, Long Noncoding|Risk Factors|Case-Control Studies 86 DUSP22 31185018 PLoS ONE 2019 PMC6559655 10.1371/journal.pone.0217846 0 0 0 208 Humans|*DNA Copy Number Variations|Genome-Wide Association Study|Genetic Predisposition|Genetic Loci|Polymorphism, Single Nucleotide|Number, Gene Copy|Gene Frequency|Case-Control Studies|Cohort Studies|*Inflammatory Bowel Disease 86 DUSP22 31142510 Cancer Res. 2019 10.1158/0008-5472.CAN-18-1037 1 1 0 208 Humans|*Ribose|ADP Ribose, Poly|poly ADP-ribose glycohydrolase|*Glycoside Hydrolases|DUSP22 protein, human|*Mitogen-Activated Protein Kinase Phosphatases|*Dual-Specificity Phosphatases|Poly(ADP-ribose) Polymerases|DNA Damage|*Lung Cancer|HeLa Cells|Mutation|Adenosine Diphosphate 86 DUSP22 31125630 Hum. Pathol. 2019 10.1016/j.humpath.2019.05.007 0 2 0 208 Humans|*Lymphoma, Large-Cell, Anaplastic|*Breast Implants|*DNA Copy Number Variations|In Situ Hybridization, Fluorescence|CD274 protein, human|*Programmed Cell Death 1 Ligand 1|Breast Implantation|DUSP22 protein, human|Mitogen-Activated Protein Kinase Phosphatases|Dual-Specificity Phosphatases|Immunohistochemistry|STAT3 protein, human|STAT3 Transcription Factor|Gigantomastia|Breast|Biomarkers, Tumor|Lymphocytes, Tumor-Infiltrating|Gene Amplification 86 DUSP22 31101622 Blood 2019 PMC6598380 10.1182/blood.2019000626 2 6 0 208 ALK protein, human|Anaplastic Lymphoma Kinase|Lymphomas, Anaplastic Large-Cell|Receptor Protein-Tyrosine Kinases|Gene Rearrangement|Gene Expression Regulation, Neoplastic|*Databases, Genetic 86 DUSP22 30715169 Aesthet Surg J 2019 10.1093/asj/sjy311 5 0 0 208 Humans|*Lymphoma, Large-Cell, Anaplastic|*Breast Implants|Breast Implantation|Lymphoma, Primary Cutaneous Anaplastic Large Cell|Anaplastic Lymphoma Kinase|Receptor Protein-Tyrosine Kinases|STAT3 protein, human|STAT3 Transcription Factor|Skin Neoplasms 86 DYM 31873734 Mol. Biol. Evol. 2019 10.1093/molbev/msz298 0 0 0 40 Animals|gluconolactonase|Carboxylic Ester Hydrolases|Phosphoric Triester Hydrolases|Active Site|Paraoxonase 1|Protein Conformation|Substrate Specificity|Crystallography, X-Ray|Catalysis|Mutations 325 DYM 31735226 Dent. Clin. North Am. 2019 10.1016/j.cden.2019.08.016 1 0 0 40 United States|Oral Health|United States Public Health Service|Health Status|Health Services Accessibility|Health Promotion 325 DYM 31589582 Radiographics 2019 10.1148/rg.2019190012 0 0 0 40 Humans|*Neck|Gland, Thyroid|*Emergency Department|Tomography, X-Ray Computed|*Pancreas 325 DYM 31444298 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6744907 10.1073/pnas.1908903116 1 4 0 40 Animals|Shaker Superfamily of Potassium Channels|Kv1.2 Potassium Channel|Potassium Channels|Ion Channel Gating|Membrane Potentials|Potassium Channel Blockers|*Toxins, Biological|Patch-Clamp Techniques|Xenopus laevis|Conotoxins|Protein Binding|Oocytes 325 DYM 31442220 PLoS Comput. Biol. 2019 PMC6728052 10.1371/journal.pcbi.1007207 3 0 0 40 Humans|*Antibody Affinity|Immunoglobulin Variable Region|Immunoglobulin Heavy Chains|Immunoglobulin Light Chains|immunoglobulin B|Immunoglobulin Fragments|Protein Engineering|Amino Acid Sequence|Peptide Library|Mutagenesis, Site-Directed|Antigens|Models, Molecular 325 EBF3 31527506 Sensors (Basel) 2019 PMC6767659 10.3390/s19184001 1 0 0 150 *Electrons|Reproducibility of Results|Algorithm|Image Processing, Computer-Assisted|Laser 75 EBF3 31383000 Clin Epigenetics 2019 PMC6683458 10.1186/s13148-019-0710-5 0 1 0 150 *DNA Methylation|Epigenesis, Genetic|*Neoplastic Processes|Promoter Regions, Genetic|Melanoma, Cutaneous Malignant|Melanoma|Skin Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 75 edil3 31869263 Curr. Eye Res. 2019 10.1080/02713683.2019.1656748 0 0 0 230 115 edil3 31817673 Int J Mol Sci 2019 PMC6941134 10.3390/ijms20246162 0 0 0 230 Humans|*Triple-Negative Breast Cancer|MicroRNAs|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|3' Untranslated Regions|Cell Line, Tumor|*Neoplastic Processes|MIRN137 microRNA, human 115 edil3 31358619 J. Biol. Chem. 2019 PMC6779430 10.1074/jbc.RA119.009799 0 0 0 230 Animals|*Biomineralization|*Egg Shell|MFGE8 protein, human|*Milk Proteins|*Glycoproteins|*Antigens, Surface|Calcification, Physiologic|Chickens|Eggs|Proteomics|Minerals 115 edil3 31330520 Oncology 2019 10.1159/000501340 0 1 0 230 Humans|*Tamoxifen|Antineoplastic Agents, Hormonal|Drug Resistance, Neoplasm|Cell Line, Tumor|MCF-7 Cells|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction|RNA, Small Interfering 115 edil3 31110935 J Bone Oncol 2019 PMC6512748 10.1016/j.jbo.2019.100238 0 0 0 230 Mice|Animals|*Osteogenesis|*Myeloid-Derived Suppressor Cells|Cell Line, Tumor|Osteoclast|Carrier Proteins 115 edil3 30961491 Curr Pharm Biotechnol 2019 PMC6806535 10.2174/1389201020666190408112822 0 0 0 230 Humans|Female|*Endometrial Cancer|Neovascularization, Pathologic|Neoplasm Grading|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Tumor Microenvironment|EDIL3 protein, human|Carrier Proteins 115 edil3 30885428 Trends Mol Med 2019 PMC6488420 10.1016/j.molmed.2019.02.010 7 0 0 230 Inflammation|Neutrophils|Phagocytosis|Periodontitis|Leukocytes|Integrins|Immunomodulation|*Immunologic Factors|Homeostasis|Myelopoiesis 115 edil3 30743056 Neurobiol. Aging 2019 10.1016/j.neurobiolaging.2019.01.003 0 0 0 230 Animals|Mice|*Mice, Inbred C57BL|*Prion Disease|Prions|PrPSc Proteins|Microglia|Prion Protein|Phagocytosis|Brain|MFGE8 protein, human|Antigens, Surface|Inflammation|Milk Proteins|Disease Progression|Scrapie|Mfge8 protein, mouse 115 edil3 30716086 PLoS ONE 2019 PMC6361458 10.1371/journal.pone.0211647 1 22 0 230 Humans|Ehlers-Danlos syndrome type 1|*Ehlers-Danlos Syndrome|*Transcriptome|Type V Collagen|*Fibroblasts|Skin Abnormalities|*Transcriptome Profiling|Extracellular Matrix|FN1 protein, human|Fibronectin|Collagen|Connective Tissues|Cells, Cultured|Mutations|Haploinsufficiency|Integrins|Genes, cdc|Joint Hypermobility 115 EFHD2 31742960 Neurosignals 2019 10.33594/000000179 0 0 0 299 *EF Hand Motifs|Calcium-Binding Proteins|*Personality Disorders|*Brain Disorders|2,5-dichloro-4-bromophenol|*Chlorophenols|*Personality|Actins 54 EFHD2 31665741 Nucleic Acids Res. 2019 PMC6821187 10.1093/nar/gkz738 2 2 0 299 Humans|*Homologous Recombination|DNA Replication|DNA Repair|Rad51 Recombinase|DNA Breaks, Double-Stranded|DNA Damage|Genomic Instability|DNA-Binding Proteins|Sister Chromatid Exchanges|DNA, Single-Stranded|PDS5B protein, human|Transcription Factors 54 EFHD2 31456657 Front Neurosci 2019 PMC6700279 10.3389/fnins.2019.00845 1 8 0 299 *tau Proteins|Neurofibrillary Tangles|Alzheimer Disease|Calcium-Binding Proteins|Brain|Phosphorylation|Protein Domains|Biophysical Phenomena 54 EFHD2 30763573 Exp. Mol. Pathol. 2019 10.1016/j.yexmp.2019.02.001 4 0 0 299 Mice|Animals|*Proteomics|*Lung|Mammary Neoplasms, Experimental|Lung Neoplasms|Cell Line, Tumor|Mice, Inbred BALB C|Gene Expression Profiling|Disease Models, Animal|Tumor Microenvironment 54 EFHD2 30710300 Methods Mol. Biol. 2019 10.1007/978-1-4939-9030-6_38 0 2 0 299 *Podosomes|*Imaging, Three-Dimensional|Actin|Cell Migration|Calcium-Binding Proteins|Microfilament Proteins|Extracellular Matrix|Cell Line, Tumor 54 EFHD2 30710299 Methods Mol. Biol. 2019 10.1007/978-1-4939-9030-6_37 0 0 0 299 Humans|*RNA|EFHD2 protein, human|*Calcium-Binding Proteins|Actins 54 EGR3 31858986 Biol. Psychiatry 2019 10.1016/j.biopsych.2019.10.019 0 0 0 1777 Male|*Nucleus Accumbens|*Cocaine|*Self Administration|Drug-Seeking Behavior|Dopamine Uptake Inhibitors|Cocaine-Related Disorders|Receptors, Dopamine D1|Receptors, Dopamine D2|Conditioning, Operant|Extinction, Psychological|Transcription Factor, EGR3|Neurons|Cues|*Neurites 305 EGR3 31844885 J. Infect. Dis. 2019 10.1093/infdis/jiz641 0 0 0 1777 Child|Humans|Animals|*Schistosoma haematobium|*Praziquantel|*Transcriptome|Schistosomiasis haematobia|IL2RA protein, human|Interleukin-2 Receptor alpha Subunit|Cytokines|T Cells 305 EGR3 31734897 Mol. Biol. Rep. 2019 10.1007/s11033-019-05189-5 1 1 0 1777 Male|Mice|Animals|*C57BL Mice|PAX7 protein, human|PAX7 Transcription Factor|Satellite Cells, Skeletal Muscle|Muscle Development|Regeneration|Muscle, Skeletal|Cell Differentiation|Cell Proliferation|Cells, Cultured|Wound Healing|mRNA|shRNA 305 EGR4 31852273 Artif Cells Nanomed Biotechnol 2019 10.1080/21691401.2019.1699808 0 0 0 95 Humans|*Gramicidin|*Cholangiocarcinoma|Bile Duct Neoplasms|*Cell Proliferation|Downregulation|Cell Line, Tumor|Antineoplastic Agents|*Cell Cycle|Signal Transduction|Bile Ducts, Intrahepatic 82 EGR4 31844579 PeerJ 2019 PMC6907094 10.7717/peerj.8183 0 0 0 95 Humans|*Prognosis|Disease-Free Survival|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|*Databases, Factual|Cell Proliferation|Carcinogenesis|RNA, Messenger|*Mammary Carcinoma, Human 82 EGR4 31617717 J. Agric. Food Chem. 2019 10.1021/acs.jafc.9b05872 0 0 0 95 *Ergosterol|*Biosynthetic Pathways|Monascus|Pigments, Biological|*Cell Membrane Permeability|Fermentation|Permeability 82 EGR4 31522019 Pharmacol Rep 2019 10.1016/j.pharep.2019.05.011 0 0 0 95 Animals|Mice|*Genes, Immediate-Early|cathinone|Alkaloids|Methamphetamine|Corpus Striatum|Central Nervous System Stimulants|Cocaine|Amfetamine|Proto-Oncogene Proteins c-fos|mRNA|Neostriatum|Dopamine 82 EGR4 31326869 Epilepsy Behav 2019 10.1016/j.yebeh.2019.06.023 0 1 0 95 Rats|Animals|*Memory|*Synaptic Plasticity|*Status Epilepticus|Maze Learning|Hippocampus|Brain-Derived Neurotrophic Factor|Cognition|Behavior, Animal|Pentylenetetrazole 82 EGR4 31204630 J Dev Orig Health Dis 2019 PMC6848762 10.1017/S2040174419000175 0 0 0 95 Pregnancy|Infant, Newborn|Humans|Female|Adult|*Birth Weight|Prospective Studies|Cohort Studies|Diabetes, Gestational|Infant, Low Birth Weight|Body Mass Index|Pregnancy Complications|Obesity|Prenatal Exposure Delayed Effects 82 EGR4 30872090 Brain Behav. Immun. 2019 10.1016/j.bbi.2019.03.006 2 0 0 95 Animals|Humans|Female|Mice|Male|Adult|Child|*Gastrointestinal Microbiome|Maternal Deprivation|*Mice, Inbred C3H|Anxiety|*Brain|Pituitary-Adrenal System|Corticosterone|Social Behavior|Behavior, Animal|Stress, Psychological|Microbiota|Animals, Newborn|Sex Differences|Compulsive Behavior|Anxiety Disorders|Cortex, Prefrontal|Mice, Inbred Strains|*Habits 82 EIF1AY 31817322 Genes (Basel) 2019 PMC6947224 10.3390/genes10121010 0 0 0 31 Female|Male|Pregnancy|Swine|Animals|*Sex Determination Analysis|Sex Differentiation|Sequence Analysis, RNA|Transcriptome|Sexual Dimorphism|Embryo, Mammalian|Gene Expression Regulation, Developmental|Fetuses|RNA 26 EIF1AY 31579209 Curr Urol 2019 PMC6771061 10.1159/000499295 0 0 0 31 26 EIF1AY 31475374 Anim. Genet. 2019 10.1111/age.12841 1 0 0 31 Cattle|Male|Animals|Y Chromosome|Spermatogenesis|Testis|Fertility|Hybridization, Genetic|Phylogeny|RNA, Messenger 26 EIF1AY 30760267 Reprod. Biol. 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Genet. 2019 PMC6849225 10.1186/s12881-019-0915-7 0 0 0 742 *Pulmonary Arterial Hypertension|*Familial Primary Pulmonary Hypertension|*Hypertension, Pulmonary|EIF2AK4 protein, human|*Protein-Serine-Threonine Kinases|*Mutations|*Hemangioma, Capillary|Pulmonary Veno-Occlusive Disease|Pedigree|Genetic Predisposition to Disease 307 EIF2AK4 31685988 Nat. Cell Biol. 2019 PMC6927814 10.1038/s41556-019-0408-0 1 8 0 742 Humans|Mice|Animals|*EIF-2|*Colorectal Cancer|*Apoptosis|EIF2B5 protein, human|Eukaryotic Initiation Factor-2B|Proto-Oncogene Proteins c-myc|Protein-Serine-Threonine Kinases|Phosphorylation|Signal Transduction|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|*Cytoplasm|Cell Proliferation|Cell Line, Tumor 307 EIF2AK4 31647517 Biochem. Soc. 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Cancer Res. 2019 PMC6942226 10.1158/1541-7786.MCR-19-0187 0 4 0 678 MicroRNAs|Neuroblastoma|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Differentiation 195 ELF4 31481969 Front Plant Sci 2019 PMC6713714 10.3389/fpls.2019.01057 0 0 0 678 Arabidopsis Proteins|Arabidopsis|Gene Expression Regulation, Plant|Circadian Clocks|Transcription Factors|Circadian Rhythm|Repressor Proteins|Plants, Genetically Modified|Light|*Luciferase|Promoter Regions, Genetic|Phenotype 195 ELF4 31191580 Front Plant Sci 2019 PMC6540683 10.3389/fpls.2019.00667 1 7 0 678 Arabidopsis|Arabidopsis Proteins|Gene Expression Regulation, Plant|Transcription Factors|Clock, Circadian|Circadian Rhythm|*Protein Processing, Post-Translational|*Luciferase|TOC1 protein, Arabidopsis 195 ELF4 31167915 J. Virol. 2019 PMC6675888 10.1128/JVI.00336-19 3 3 0 678 Sheep|Animals|*Bluetongue virus|Tongue, Blue|S10 protein, Bluetongue virus|*Viral Nonstructural Proteins|Ceratopogonidae|Virus Replication|*Extracellular Signal-Regulated MAP Kinases|Host-Pathogen Interactions|Signal Transduction|Cell Line 195 ELF4 31152338 Mol. Biol. Rep. 2019 10.1007/s11033-019-04894-5 0 0 0 678 *Quantitative Trait Loci|*Genotype|*Perilla|Chromosome Mapping|Genetic Linkage|Genotyping Techniques|Illumina Sequencing|Phenotype|Sequence Analysis, DNA|Polymorphism, Single Nucleotide|Gene Library 195 ELF4 31060678 Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2019 10.3881/j.issn.1000-503X.10613 0 3 0 678 Humans|Female|*Uterine Cervical Neoplasms|*RNA, Micro|*Cervix Uteri|HeLa Cells|Cervical Intraepithelial Neoplasia|Uterine Cervical Dysplasia|Cell Proliferation|Gene Expression Regulation, Neoplastic|Squamous Cell Carcinoma|Cell Line, Tumor|Apoptosis|Up-Regulation|Quantitative Real Time Polymerase Chain Reaction|Immunohistochemistry|Transfection|ELF4 protein, human|DNA-Binding Proteins|Transcription Factors 195 ELF4 30917931 Gene 2019 10.1016/j.gene.2019.03.047 1 2 0 678 *Arabidopsis|Phylogeny|Arabidopsis Proteins|ELF4 protein, human|Transcription Factors|Gene Expression Regulation, Plant|Clock, Circadian|Flowers|DNA-Binding Proteins|Photoperiod|Genes, Plant|Phenotype|Circadian Rhythm|Amino Acid Sequence|Mutation|Light|Sequence Alignment 195 ELF4 30898878 J. 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Chem. 2019 PMC6514618 10.1074/jbc.RA118.006321 1 1 0 678 Plasmodium yoelii|Parasitemia|Malaria|Host-Parasite Interactions|Platelet Factor 4 195 ELF4 30890658 Sci Signal 2019 PMC6893850 10.1126/scisignal.aau4604 2 5 0 678 Mice|Animals|*Type I Interferon|Hipk2 protein, mouse|*Protein-Serine-Threonine Kinases|HIPK2 protein, human|Vesiculovirus|Vesicular Stomatitis|Vesicular stomatitis Indiana virus|Immunity, Innate|*Antiviral Agents|Macrophages|Phosphorylation|Signal Transduction|Virus Replication|Elf4 protein, mouse|DNA-Binding Proteins|Transcription Factors 195 ELF4 30774641 Front Plant Sci 2019 PMC6367231 10.3389/fpls.2019.00057 3 1 0 678 *Arabidopsis|*Circadian Clocks|*Temperature|Arabidopsis Proteins|Gene Expression Regulation, Plant|Transcription Factors|Circadian Rhythm|Promoter Regions, Genetic|Histone 195 ELF4 30606777 Plant Cell 2019 PMC6391688 10.1105/tpc.18.00721 7 2 0 678 *Histone Deacetylase|Arabidopsis Proteins|Arabidopsis|Gene Expression Regulation, Plant|Histones|Transcription Factors|Flowers|Photoperiod|Acetylation|*Epigenetic|Chromosomal Proteins, Non-Histone|HDA9 protein, Arabidopsis|Hos15 protein, Arabidopsis 195 ELF5 31861377 Cancers (Basel) 2019 PMC7017076 10.3390/cancers12010006 2 0 0 292 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Prognosis|Biomarkers, Tumor|Cluster Analyses|Gene Expression 183 ELF5 31782121 Trop Anim Health Prod 2019 10.1007/s11250-019-02119-2 0 2 0 292 Animals|*Goat|*Whey Proteins|*Breeding|*Whey|Haplotypes|SNPs|Gene Frequency|Milk|Genotype|TYRP1 protein, human|*Membrane Glycoproteins|Milk Protein|3' UTR|Promoter Regions, Genetic|Exons 183 ELF5 31557407 J. 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Biophys. 2019 10.1016/j.abb.2019.108226 2 0 0 234 Humans|ADP-Ribose|ADP Ribosylation|ADP Ribose Transferases|Poly(ADP-ribose) Polymerases|Sirtuins|Acetylation|NAD|Substrate Specificity|Active Site|Stability, Genome|SIRT7 protein, human 110 ELK4 31794091 Prostate 2019 PMC7302117 10.1002/pros.23932 0 2 0 234 Humans|Male|Neoplasm Recurrence, Local|*ets-Domain Protein Elk-1|AR protein, human|Androgen Receptor|*Prostate Cancer|Prostate|Cell Line, Tumor|Protein Binding|ELK1 protein, human 110 ELK4 31592503 JCO Precis Oncol 2019 PMC6778956 10.1200/PO.19.00047 0 0 0 234 Humans|*Neoplasms|Precision Medicine|Transcriptome Analysis|Mutation|Sequencing, Whole Exome|Genomics|Genetic Predisposition to Disease 110 ELK4 31461342 Am. J. 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Commun. 2019 10.1016/j.bbrc.2019.02.048 0 0 0 271 Mice|Animals|*Mouse Embryonic Stem Cells|*Cell Differentiation|Embryoid Bodies|*Organogenesis|Cardiomyocytes|Germ Layers|Mesoderm|Cell Proliferation|Embryo, Mammalian 97 EMP2 30646013 Invest. Ophthalmol. Vis. Sci. 2019 PMC6336205 10.1167/iovs.18-24345 3 1 0 271 Animals|*Corneal Neovascularization|Eye Burns|Burns, Chemical|Cornea|Neovascularization, Pathologic|Vascular Endothelial Growth Factor A|Angiogenesis Inhibitors|immunoglobulin B|*Immunoglobulins|Sodium Hydroxide|Disease Models, Animal|Membrane Proteins 97 Emx1 31827197 Sci Rep 2019 PMC6906436 10.1038/s41598-019-55463-6 0 3 0 107 Humans|*Gene Editing|*Real-Time Polymerase Chain Reaction|gRNA|CRISPR-Cas Systems|CRISPR|Mutagenesis, Site-Directed|Genome|Cells, 293T|*Clones|INDEL Mutation|DNA|Genotype|HOXB13 protein, human|Homeodomain Proteins 206 Emx1 31749685 Front Cell Neurosci 2019 PMC6844266 10.3389/fncel.2019.00454 0 0 0 107 Animals|*Neocortex|*Axons|*Pyramidal Neurons|Neurons|Contactin 2|Cell Adhesion Molecules, Neuronal|Animals, Newborn 206 Emx1 31708734 Front Neurosci 2019 PMC6819314 10.3389/fnins.2019.01141 0 0 0 107 Mice|Animals|*RNA, Micro|*Embryonic Stem Cells|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Cell Differentiation|Pluripotent Stem Cell|Mouse Embryonic Stem Cell|*Interneurons|Motor Neurons|Bcl11b protein, mouse|Repressor Proteins|Tumor Suppressor Proteins 206 Emx1 31608978 J. 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Ther. 2019 PMC6882235 10.1186/s13075-019-2058-9 0 0 0 246 Humans|*Osteoarthritis, Knee|*Adipocyte|*Adipose Tissue|Subcutaneous Fat|Culture Media, Conditioned 409 EN1 31742552 Elife 2019 PMC6890462 10.7554/eLife.50617 0 0 0 246 Mice|Animals|*Cerebellar Nuclei|*Purkinje Cells|*Number, Cell|Homeo Box Genes|Cerebellum|Homeodomain Proteins|Gene Expression Regulation, Developmental|*Neurons|Nerve Tissue Proteins 409 EN1 31710242 J. Comput. Biol. 2019 10.1089/cmb.2019.0138 0 0 0 246 *DNA Methylation|*Transcriptome|*Carcinoma, Squamous Cell|*Carcinoma, Non-Small-Cell Lung|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Lung Neoplasms|Gene Regulatory Networks|MicroRNAs|Gene Expression Profiling 409 EN1 31654838 Lung Cancer 2019 10.1016/j.lungcan.2019.10.002 1 0 0 246 Humans|*Crizotinib|*Carcinoma, Non-Small-Cell Lung|alectinib|Quality of Life|*Lung Neoplasms|*Carbazoles|*Piperidines|Anaplastic Lymphoma Kinase|Receptor Protein-Tyrosine Kinases|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Pyridines|Pyrazoles|Brain Neoplasms|*Reported Outcomes, Patient 409 EN1 31576231 PeerJ 2019 PMC6752186 10.7717/peerj.7414 1 0 0 246 *Prognosis|*Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|EN1 protein, human|*Homeodomain Proteins|Mutation 409 EN1 31524742 Ann Plast Surg 2019 10.1097/SAP.0000000000001788 0 0 0 246 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|Neoplasm Recurrence, Local|*Lymph Node Excision|Lymph Nodes|Lymphatic Metastasis|Prognosis|Neoplasm Staging|Biopsy|*Chronic Disease|*Relapse 409 EN1 31513565 PLoS Biol. 2019 PMC6759197 10.1371/journal.pbio.3000447 4 0 0 246 Mice|Animals|*Animals, Newborn|*Interneurons|*Locomotor Activity|Motoneurons|Spinal Cord|EN1 protein, human|Homeodomain Proteins|Electric Stimulation|Patch-Clamp Techniques|N-Methylaspartate|Serotonin 409 EN1 31412760 BMC Genet. 2019 PMC6693279 10.1186/s12863-019-0771-7 2 0 0 246 Animals|Female|*Genome-Wide Association Study|*Chickens|*Eggs|Phenotype|Quantitative Trait Loci|Linkage Disequilibrium|Oviposition|Genotype|Polymorphism, Single Nucleotide|Rhode Island 409 EN1 31366379 BMC Res Notes 2019 PMC6670129 10.1186/s13104-019-4511-x 0 0 0 246 Humans|*Zika Virus|Zika Virus Infection|*Retrospective Studies|Mozambique|*Immunoglobulin M|Antibodies, Viral|*Fever|Immunoglobulin G|Enzyme-Linked Immunosorbent Assay 409 EN1 31310118 J. Agric. Food Chem. 2019 10.1021/acs.jafc.9b02728 0 0 0 246 *Gluten Proteins|*Bread|*Triticum|*Amino Acids|Flour|Gliadin|Molecular Weight 409 EN1 31239270 Cancer Res. 2019 PMC6698222 10.1158/0008-5472.CAN-18-3264 5 0 0 246 Humans|Triple-Negative Breast Cancer|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Transcription Factors|Cell Proliferation|Xenograft Model Antitumor Assays|MCF-7 Cells 409 EN1 31081218 J. Cell. Physiol. 2019 10.1002/jcp.28804 1 0 0 246 Humans|Gene Regulatory Networks|RNA, Micro|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Upregulation|Triple-Negative Breast Cancers|Bioinformatic|Gene Expression Profiling|RNA, Messenger|Gene Ontology|Down-Regulation|Transcriptome|Cell Line, Tumor|FOXM1 protein, human|Forkhead Box Protein M1 409 EN1 31069529 J. Neurol. 2019 10.1007/s00415-019-09358-1 1 0 0 246 Humans|*Genetic Testing|High-Throughput Nucleotide Sequencing|*Disorders, Neurological|*Asian Continental Ancestry Group|Mutation|Genetic Predisposition to Disease 409 EN1 31055077 Nanomedicine 2019 10.1016/j.nano.2019.04.006 2 2 0 246 Humans|*Docetaxel|*Triple-Negative Breast Cancers|*Nanoparticles|arginyl-glycyl-aspartic acid|*Oligopeptides|Antineoplastic Agents|Cell Line, Tumor|Peptides|Apoptosis|Xenograft Model Antitumor Assays|Viability, Cell|Homeodomain Proteins|Transcription Factors 409 EN2 31790140 J. Biochem. 2019 10.1093/jb/mvz097 0 15 0 265 Humans|Male|Mice|Animals|*RNA, Long Noncoding|Mice, Nude|*Prostate Cancer|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Proliferation|MicroRNAs|Up-Regulation|Cell Movement|Epigenesis, Genetic|PC3 Cells|Cell Line, Tumor|Tumorigenesis|EZH2 protein, human|Enhancer of Zeste Homolog 2 Protein 290 EN2 31742552 Elife 2019 PMC6890462 10.7554/eLife.50617 1 0 0 265 Mice|Animals|*Cerebellar Nuclei|*Purkinje Cells|*Number, Cell|Homeo Box Genes|Cerebellum|Homeodomain Proteins|Gene Expression Regulation, Developmental|*Neurons|Nerve Tissue Proteins 290 EN2 31692391 Biomarkers 2019 10.1080/1354750X.2019.1690047 0 0 0 265 290 EN2 31524742 Ann Plast Surg 2019 10.1097/SAP.0000000000001788 0 0 0 265 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|Neoplasm Recurrence, Local|*Lymph Node Excision|Lymph Nodes|Lymphatic Metastasis|Prognosis|Neoplasm Staging|Biopsy|*Chronic Disease|*Relapse 290 EN2 31500112 J Clin Med 2019 PMC6780828 10.3390/jcm8091400 1 3 0 265 Humans|Male|*Genes, Homeobox|*Prostate Cancer|Prostate|AR protein, human|Androgen Receptor|*Oncogenes|Homeodomain Proteins|Tumor Cell Lines|Biomarkers, Tumor|*Oncogenesis|PC3 Cells|Cell Proliferation|Nerve Tissue Proteins 290 EN2 31428500 Case Rep Psychiatry 2019 PMC6681604 10.1155/2019/3954161 0 0 0 265 Humans|*Energy Drinks|Caffeine|Central Nervous System Stimulants|*Food|*Psychosis|*Failure, Renal 290 EN2 31412760 BMC Genet. 2019 PMC6693279 10.1186/s12863-019-0771-7 2 0 0 265 Animals|Female|*Genome-Wide Association Study|*Chickens|*Eggs|Phenotype|Quantitative Trait Loci|Linkage Disequilibrium|Oviposition|Genotype|Polymorphism, Single Nucleotide|Rhode Island 290 EN2 31310118 J. 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Food Chem. 2019 10.1021/acs.jafc.9b02728 1 0 0 265 *Gluten Proteins|*Bread|*Triticum|*Amino Acids|Flour|Gliadin|Molecular Weight 290 enho 31781629 Biomed Res Int 2019 PMC6855013 10.1155/2019/6128410 1 0 0 175 Child|Humans|*Diabetes Mellitus, Type 1|Glycoproteins|Insulin Resistance|Carrier Proteins|Serum Albumin, Human|Case-Control Studies 105 enho 31775661 BMC Nephrol 2019 PMC6882244 10.1186/s12882-019-1619-0 0 1 0 175 Humans|*Receptors, Calcium-Sensing|*Cross-Sectional Studies|*Renal Dialysis|*Dyslipidemia|Single Nucleotide Polymorphisms|Gene Frequency|Genotype|Case-Control Studies|Liver X Receptor|CASR protein, human|Enho protein, human|Blood Proteins|Peptides 105 enho 31756066 Adv Clin Exp Med 2019 10.17219/acem/104551 1 0 0 175 Female|Humans|Pregnancy|*Chronic Kidney Disease|*Hypertension|Glomerular Filtration Rate|Fibronectins|Blood Proteins|Insulin Sensitivity|Peptides|*Transcription Factors|Gestational Diabetes Mellitus|Diabetes Mellitus, Type 2 105 enho 31674937 Anatol J Cardiol 2019 PMC6955056 10.14744/AnatolJCardiol.2019.90349 0 0 0 175 Humans|*Angina, Stable|*Coronary Vessels|*Dilatation, Pathologic|Coronary Angiography|*Coronary Aneurysm|Coronary Artery Disease|Case-Control Studies|Biomarkers 105 enho 31438729 Hypertens Pregnancy 2019 10.1080/10641955.2019.1657887 1 0 0 175 105 enho 31400396 Mol. 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Genomics 2019 PMC6732414 10.1152/physiolgenomics.00037.2019 3 0 0 175 Mice|Rats|Animals|*Insulin Resistance|*Blood Glucose|Diabetes Mellitus, Type 2|Macaca mulatta|*Liver|Diet, High-Fat|Mice, Obese|MicroRNAs|Insulin|Glucose|Gene Expression Regulation|Signal Transduction|MIRN29 microRNA, mouse|MIRN29 microRNA, rat 105 enho 31209831 Obes Surg 2019 10.1007/s11695-019-03998-y 0 0 0 175 Humans|preptin|*Bariatric Surgery|*Obesity|*Peptide Fragments|*Insulin-Like Growth Factor II|Obesity, Morbid|Fibronectins|Energy Metabolism|*Transcription Factors 105 enho 31202835 Metab. Clin. 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Res. 2019 10.1016/j.phrs.2019.104594 0 0 0 12 Humans|Dihydrouracil Dehydrogenase (NADP)|Capecitabine|Fluorouracil|Antimetabolites, Antineoplastic|Thymidylate Synthase|Polymorphism, Genetic|Alleles|Genotype|Colorectal Neoplasms|*Antimetabolites|Hand-Foot Syndrome|TYMS protein, human 23 ENOSF1 31486228 Cancer Med 2019 PMC6797583 10.1002/cam4.2529 1 0 0 12 Humans|*Prospective Studies|*Mobile Applications|Dihydrouracil Dehydrogenase (NADP)|Capecitabine|Fluorouracil|*Genetic Testing|Antimetabolites, Antineoplastic|Antineoplastic Combined Chemotherapy Protocols|Polymorphism, Single Nucleotide|*Germ Line 23 EPB41L4A 31712638 Sci Rep 2019 PMC6848163 10.1038/s41598-019-52935-7 1 0 0 29 Humans|*Tooth Eruption|*Methyltransferase, Histone|*Tooth Abnormalities|Pedigree|Single Nucleotide Polymorphism|Exome|KMT2D protein, human|*DNA-Binding Proteins|KMT2C protein, human|Failure of Tooth Eruption, Primary|Tooth Diseases|Genetic Linkage|Genotypes|Phenotype|Sequencing, Whole Exome|Receptor, Parathyroid Hormone, Type 1|Haplotypes|Dentition, Permanent 30 EPB41L4A 31671345 Mol Ther Nucleic Acids 2019 PMC6838551 10.1016/j.omtn.2019.09.017 0 45 0 29 Pregnancy|Humans|Female|*RNA, Long Noncoding|*Trophoblasts|*Abortion, Spontaneous|Cell Proliferation|Glycolysis|Upregulation 30 EPB41L4A 31645082 Exp. Physiol. 2019 10.1113/EP087847 2 1 0 29 Humans|Female|*RNA, Long Noncoding|*RNA, Micro|*Transcription Factor|*Carcinoma, Ovarian Epithelial|*Upregulation|*Ovarian Cancer|Cell Proliferation|*Disease Progression|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Movement|*Transcriptional Activation|Cell Line, Tumor|Downregulation|RUNX1T1 protein, human|RUNX1 Translocation Partner 1 Protein 30 EPB41L4A 31612476 J. Cell. Physiol. 2019 10.1002/jcp.29217 1 0 0 29 *RNA, Long Noncoding|*Mesenchymal Stem Cells|*Bone Marrow|RNA, Micro|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Cycle|Xenograft Model Antitumor Assays|Signal Transduction 30 EPB41L4A 31403267 Adv Clin Exp Med 2019 10.17219/acem/94392 1 0 0 29 *RNA, Long Noncoding|*Small Cell Lung Carcinoma|*Alternative Splicing|*Sequencing, RNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|MicroRNAs|Biomarkers, Tumor|Prognosis|Gene Expression Profiling|RNA, Messenger|*Whole Exome Sequencing|Lung Neoplasms 30 EPB41L4A 31229557 Genomics 2019 10.1016/j.ygeno.2019.06.012 1 0 0 29 Humans|Female|*Uterine Cervical Neoplasms|LincRNAs|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|DNA Methylation|Downregulation|*Carcinoma 30 EPB41L4A 30971290 J. Exp. Clin. Cancer Res. 2019 PMC6458726 10.1186/s13046-019-1128-9 10 6 0 29 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Epithelial-Mesenchymal Transition|Hep G2 Cells|Cell Line, Tumor|Cell Movement 30 EPB41L4A 30959550 Mol Oncol 2019 PMC6547626 10.1002/1878-0261.12489 6 2 0 29 Humans|Female|*RNA, Long Noncoding|*Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Regulatory Networks|RNA, Messenger|Gene Ontology|Sequencing, RNA 30 EPB41L4A 30944630 Oncol Lett 2019 PMC6444437 10.3892/ol.2019.10114 3 1 0 29 XIST non-coding RNA|*RNA, Long Noncoding|*Glioblastoma|miRNA|Prognosis|Gene Regulatory Networks|mRNA|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling 30 EPB41L4A 30882937 J. Cell. Biochem. 2019 10.1002/jcb.28554 1 0 0 29 *RNA, Long Noncoding|*Brain Ischemia|*Stroke|Messenger RNA|Gene Regulatory Networks|RNA, Micro|Gene Expression Profiling|Transcriptome|Biomarkers 30 EPB41L4A 30854042 Oncol Lett 2019 PMC6365949 10.3892/ol.2019.9936 6 4 0 29 *RNA, Long Noncoding|*Prognosis|*Colorectal Cancer|miRNA|*Colonic Neoplasms|mRNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Ontology|Kaplan-Meier Estimate 30 EPB41L4A 30796006 EBioMedicine 2019 PMC6444057 10.1016/j.ebiom.2019.01.035 11 9 0 29 *RNA, Long Noncoding|*Glycolysis|Gene Expression Regulation, Neoplastic|Cell Proliferation|HDAC2 protein, human|*Histone Deacetylase 2|Down-Regulation|Carcinogenesis|Cell Line, Tumor|Apoptosis|*Translocation, Genetic 30 EPB41L4A 30764831 J. Exp. Clin. Cancer Res. 2019 PMC6376750 10.1186/s13046-019-1096-0 7 5 0 29 *RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor 30 EPB41L4B 30816447 Int. J. Oncol. 2019 10.3892/ijo.2019.4732 0 2 0 90 Humans|*Lung Adenocarcinoma|A549 Cells|Lung Cancer|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Upregulation|Lung|Plasma Membrane 23 EPC2 31647967 J. Allergy Clin. Immunol. 2019 10.1016/j.jaci.2019.07.049 1 2 0 66 *Eosinophilic Esophagitis|ANO1 protein, human|*Anoctamin-1|*Esophagus|*Neoplasm Proteins|Interleukin-13|Spaces, Intercellular|Cell Proliferation 54 EPC2 31055822 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.06.024 0 0 0 66 Child|Male|Humans|Female|Chromosome Deletion|Comparative Genomic Hybridization|Developmental Disabilities|Abnormalities, Multiple|*Chromosome Structures|DNA-Binding Proteins|MBD5 protein, human 54 EPG5 31444285 J. Cell. Sci. 2019 10.1242/jcs.234195 0 5 0 85 Animals|*Lysosomes|*Autophagy|Absent corpus callosum cataract immunodeficiency|Agenesis of Corpus Callosum|Caenorhabditis elegans Proteins|Caenorhabditis elegans|Vesicular Transport Proteins|Cataract|Mutations 47 EPG5 31410206 Theranostics 2019 PMC6691579 10.7150/thno.34887 6 83 0 85 47 EPG5 31333218 Indian Pediatr 2019 0 0 0 85 Absent corpus callosum cataract immunodeficiency|*Agenesis of Corpus Callosum|*Cataract|Lysosome-Associated Membrane Glycoproteins|Corpus Callosum|Phenotype|Vesicular Transport Proteins|Mutation|Disorder, Neurodevelopmental|Immunologic Deficiency Syndromes 47 EPG5 31226715 Neuropediatrics 2019 10.1055/s-0039-1692129 0 1 0 85 Humans|Child, Preschool|Absent corpus callosum cataract immunodeficiency|*Agenesis of Corpus Callosum|*Cataract|*Phenotype|Lysosome-Associated Membrane Glycoproteins|Vesicular Transport Proteins|Mutation|EPG5 protein, human 47 EPG5 31184778 Ann. Hum. Genet. 2019 10.1111/ahg.12337 0 0 0 85 Humans|Absent corpus callosum cataract immunodeficiency|*Siblings|*Agenesis of Corpus Callosum|*Cataract|*Mutation|Exon|Lysosome-Associated Membrane Glycoproteins|Vesicular Transport Proteins|Phenotype|EPG5 protein, human 47 EPG5 30931944 Nat Commun 2019 PMC6443784 10.1038/s41467-019-09430-4 4 4 0 85 Humans|Ubiquitination|Endosomal Sorting Complexes Required for Transport|Ubiquitin Thiolesterase|Endopeptidases|Endosomes|Lysosomes|Ubiquitin|Autophagy|Protein Transport|HeLa Cells|Membrane Fusion|*Embryonic Stem Cell|HEK293 Cells|USP8 protein, human|EPG5 protein, human|Vesicular Transport Proteins|Lysosome-Associated Membrane Glycoproteins 47 EPG5 30806141 Autophagy 2019 PMC6613882 10.1080/15548627.2019.1586247 0 0 0 85 Humans|Autophagosomes|Agenesis of Corpus Callosum|Lysosomes|Lysosome-Associated Membrane Glycoproteins|Vesicular Transport Proteins|Endosomes|Autophagy|Mutations|Cataract 47 EPSTI1 31798636 Front Genet 2019 PMC6863930 10.3389/fgene.2019.01142 0 0 0 50 37 EPSTI1 31750818 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2019 0 6 0 50 Humans|*Bioinformatic|*Th1 Cells|Gene Ontology|Protein Interaction Maps|*Cell Differentiation|Th17 Cells|Gene Regulatory Networks|Gene Expression Profiling|Signal Transduction|Protein Interaction Mapping|Transcriptome|Software|Macrophages|Rheumatoid Arthritis|Interferon-gamma|IL17A protein, human|Interleukin 17A|Upregulation 37 EPSTI1 31665046 Virol. J. 2019 PMC6819563 10.1186/s12985-019-1231-8 0 0 0 50 Humans|Child|*Influenza, Human|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Computational Biology|Databases, Genetic|*Biomarkers|Cluster Analysis|Transcriptome 37 EPSTI1 31022701 Reproduction 2019 10.1530/REP-18-0561 1 0 0 50 Female|Humans|Cattle|Animals|*Oviduct|*Fallopian Tubes|*Embryo, Mammalian|Embryo Culture Techniques|*Cells, Epithelial|*Gene Expression|Co-culture|Embryonic Development|Media, Conditioned|*Cell Count|Suppressor of Cytokine Signaling Proteins|Intercellular Signaling Peptides and Proteins|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|AGR3 protein, human|Carrier Proteins|Neoplasm Proteins|ROCK1 protein, human 37 EPSTI1 30887698 J. Cell. Mol. Med. 2019 PMC6484424 10.1111/jcmm.14260 11 4 0 50 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Disease Progression|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|EPSTI1 protein, human|Neoplasm Proteins|Cell Line, Tumor|*Neoplastic Processes|RNAs, Circular|MIRN942 microRNA, human 37 ERMN 31397923 Chemistry 2019 10.1002/chem.201902637 0 0 0 57 helicenes|Polycyclic Compounds|Stereoisomerism|Models, Molecular 24 ERMN 31123898 Metab Brain Dis 2019 10.1007/s11011-019-00429-w 0 0 0 57 Humans|*Down-Regulation|*Multiple Sclerosis|*Multiple Sclerosis, Relapsing-Remitting|MicroRNAs 24 ERMN 31060905 EBioMedicine 2019 PMC6562069 10.1016/j.ebiom.2019.04.048 2 1 0 57 Humans|Child|Animals|Mice|*Epigenesis, Genetic|Sevoflurane|Maze Learning|Hippocampus|Folic Acid|*Anesthesia 24 ESPN 31677115 CEN Case Rep 2019 PMC6990314 10.1007/s13730-019-00429-w 0 0 0 80 Female|Humans|*Nephritis, Hereditary|*Exome|*Mutation|Collagen Type IV|Pedigree|Mutation, Missense|Hematuria|Basement Membrane, Glomerular|Phenotype|Hearing Loss, Sensorineural|Autoantigens|Heredity|COL4A4 protein, human 129 ESPN 31664556 Pediatr. Nephrol. 2019 10.1007/s00467-019-04378-5 0 0 0 80 Child|Humans|*Nephrology|Kidney Failure, Chronic|*Kidney|Kidney Transplantation|Healthcare Disparities|Health Services Accessibility|Europe|Registries|Survey|*Societies|Health Policies 129 ESPN 31638198 Mol Med Rep 2019 PMC6854525 10.3892/mmr.2019.10728 0 2 0 80 *Usher Syndromes|USH2A protein, human|Extracellular Matrix Proteins|Membrane Proteins 129 ESPN 31583095 Clin Kidney J 2019 PMC6768305 10.1093/ckj/sfz011 7 0 0 80 *Renal Dialysis|*Edetic Acid|*Kidney Transplantation|End Stage Renal Disease|Renal Replacement Therapy|*Registry|Survival Rate|*Transplant|Time Factors 129 ESPN 31486067 Clin. Genet. 2019 10.1111/cge.13638 2 0 0 80 Humans|*Whole Exome Sequencing|*Asian Continental Ancestry Group|Mutations|Deafness|Alleles|Connexins|Sequencing, Next-Generation|Pedigree|Frequencies, Allele|Genetic Variation|Genetic Testing|Hearing Loss|OTOF protein, human|Membrane Proteins 129 ESPN 31418062 Pediatr. Nephrol. 2019 10.1007/s00467-019-04333-4 1 0 0 80 Adult|Humans|United States|Child|Renal Dialysis|Kidney Failure, Chronic|Nephrology|Glomerular Filtration Rate|Kidney|Time Factors|Registries 129 ESPN 31389194 Mol Genet Genomic Med 2019 PMC6732339 10.1002/mgg3.917 0 0 0 80 Humans|Nonsyndromic Deafness|Pakistan|*Deafness|Nonsyndromic sensorineural hearing loss|Hearing Loss, Sensorineural|Genetic Screening|Hearing Loss|Connexins|High-Throughput Nucleotide Sequencing|Mutation|Genetic Predisposition to Disease|*Cohort Studies|*Ethnic Groups|Membrane Proteins 129 ESPN 31197263 Nat Rev Nephrol 2019 PMC7136166 10.1038/s41581-019-0161-4 2 0 0 80 Child|Adult|Humans|Renal Dialysis|Human Growth Hormone|*Chronic Kidney Disease|Growth Disorders|Renal Transplantation|Nephrology|Recombinant Proteins|Chronic Kidney Disease-Mineral and Bone Disorder 129 ESPN 31118499 Nat Rev Nephrol 2019 PMC7136168 10.1038/s41581-019-0155-2 3 0 0 80 Infant|Adult|Child|Humans|Adolescent|*Polycystic Kidney, Autosomal Dominant|Blood Pressure Monitoring, Ambulatory|*Consensus|Hypertension|Kidney|Cysts|Ultrasonography|Genetic Testing|Medical History Taking 129 ESPN 31038179 Nephrol. 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Transplant. 2019 10.1093/ndt/gfz011 0 0 0 80 Child|Adult|Humans|*Renal Dialysis|*Nephrology|*Consensus|Arteriovenous Shunt, Surgical|End Stage Kidney Disease|Central Venous Catheters|Arteriovenous Fistulas|Practice Patterns, Physicians'|Treatment Outcome 129 ESPN 30825259 Pediatr Transplant 2019 10.1111/petr.13385 0 0 0 80 Child|Humans|*Glomerulosclerosis, Focal Segmental|*Kidney Transplantation|*Nephrology|Graft Survival|Plasmapheresis|Kidney Failure, Chronic|Immunosuppressive Agents|Proteinuria|Recurrence|Treatment Outcome|*Survey 129 ESPN 30733538 Sci Rep 2019 PMC6367484 10.1038/s41598-018-38245-4 1 0 0 80 Child|Humans|Vietnam|*Mutation|*Hearing Loss|DNA Mutational Analysis|Connexins|Chinese|Deafness|Massively Parallel Sequencing|Pedigree|Alleles|Indochina|POU3F4 protein, human|POU Domain Factors 129 ESPN 30627588 Orthop J Sports Med 2019 PMC6311573 10.1177/2325967118815448 2 0 0 80 Humans|*Football|*Incidence|*Brain Concussion|*Soccer|Time Factors 129 ESPN 30618491 Cancer Cell Int. 2019 PMC6310995 10.1186/s12935-018-0713-x 0 2 0 80 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Prognosis|*Cell Proliferation|Biomarkers, Tumor|Lymphatic Metastasis|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|*Cell Cycle|*Microfilament Proteins 129 ESX1 31822682 Sci Rep 2019 PMC6904446 10.1038/s41598-019-54286-9 1 0 0 100 Familial ependymoma|Ependymoma|*Spinal Cord Neoplasms|Astrocytoma|*Glioma|Glioblastoma|*Genomics|Spinal Cord 73 ESX1 31793700 Andrologia 2019 10.1111/and.13483 0 0 0 100 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Testis|*Semen|*Spermatogenesis|Sperm Retrieval|Spermatozoa|*Biomarkers|Real Time Polymerase Chain Reaction|mRNA 73 ESX1 30815463 Kidney Dis (Basel) 2019 PMC6388444 10.1159/000492933 2 1 0 100 *Podocytes|Diabetic Kidney Disease|Kidney Glomerulus|Epigenesis, Genetic|glutamate receptor ionotropic, AMPA 3|*Receptors, AMPA|DNA Methylation|Apoptosis|*Epigenetic|Glucose|Cells, Cultured|Diabetes Mellitus 73 ETV2 31864907 Mol. Ther. 2019 PMC7002895 10.1016/j.ymthe.2019.11.019 0 0 0 295 Humans|*Cyclic AMP|*Endothelial Cells|*Signal Transduction Pathways|rap1 GTP-Binding Proteins|Guanine Nucleotide Exchange Factors|Forskolin|Cyclic AMP-Dependent Protein Kinases|*Neovascularization, Pathologic|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|TYRP1 protein, human|*Membrane Glycoproteins|Cell Line, Tumor|ETV2 protein, human|Transcription Factors 125 ETV2 31839543 Stem Cell Reports 2019 PMC6962646 10.1016/j.stemcr.2019.11.005 2 0 0 295 Humans|*Endothelial Progenitor Cells|*Pluripotent Stem Cells|Hematopoietic Stem Cells|Hematopoiesis|Induced Pluripotent Stem Cells|GATA2 protein, human|GATA2 Transcription Factor|Cell Differentiation|Gene Expression Regulation|Hematopoietic Stem Cell Transplantation 125 ETV2 31744543 Stem Cell Res Ther 2019 PMC6862833 10.1186/s13287-019-1466-8 1 5 0 295 KDR protein, human|VEGFR-2|Transcription Factor|Embryonic Stem Cells|Cell Lineage|Cell Differentiation|Gene Expression Regulation, Developmental|Endothelial Cells|Signal Transduction|Cells, Cultured 125 ETV2 31740535 Development 2019 PMC6918769 10.1242/dev.182097 1 0 0 295 Endothelial Cells|*Transcriptome|Mesoderm|Cell Differentiation|Cell Lineage|Embryonic Stem Cells|Vascular Endothelial Growth Factor Receptor-2|Transcription Factors|*B-Lymphocytes|Gene Expression Regulation, Developmental 125 ETV2 31708474 Stem Cell Reports 2019 PMC6915846 10.1016/j.stemcr.2019.10.007 0 0 0 295 Humans|*Induced Pluripotent Stem Cells|*Neutrophils|Cell Differentiation|sargramostim|Granulocyte-Macrophage Colony-Stimulating Factor|Antigens, CD34|RNA, Messenger|ETV2 protein, human|Transcription Factors 125 ETV2 31705559 Dev. Dyn. 2019 PMC7181369 10.1002/dvdy.130 1 0 0 295 Animals|*Zebrafish|Zebrafish Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Transcription Factor|Cell Differentiation|Morpholinos|Neovascularization, Physiologic|*Vascular Endotheliums|*Progenitor Cells|Hematopoiesis|Endothelial Cells|*Blood Cells|Gene Knockdown Techniques|Signal Transduction|Etsrp protein, zebrafish 125 ETV2 31591580 Nat. Methods 2019 PMC6918722 10.1038/s41592-019-0586-5 22 0 0 295 Humans|*Organoids|Human Embryonic Stem Cells|Tissue Engineering|Tissue Scaffolds|Cells, Cultured|Cell Line|*Brain|Endothelium 125 ETV2 31534512 Theranostics 2019 PMC6735401 10.7150/thno.35300 1 7 0 295 Humans|*Cardiovascular Diseases|Endothelial Cell|Vascular Endothelial Growth Factor Receptor-2|Neovascularization, Physiologic|Transcription Factor|Cell Lineage|Cell Differentiation|Vascular Endothelial Growth Factor A|Gene Expression Regulation, Developmental|Neovascularization, Pathologic|Cellular Reprogramming|3'-(1-butylphosphoryl)adenosine|ETV2 protein, human 125 ETV2 31484921 Exp. Mol. Med. 2019 PMC6802661 10.1038/s12276-019-0271-x 0 0 0 295 *Myocardial Infarction|*Cardiovascular Physiological Phenomena|Regeneration 125 ETV2 31432499 FEBS Lett. 2019 PMC6916194 10.1002/1873-3468.13585 2 0 0 295 *Blood Cell|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Hematopoietic Stem Cells|Pluripotent Stem Cells|Cell Lineage|Cell Differentiation|Mesoderm|*Gene Expression Regulation|Transcriptional Network 125 ETV2 31404653 Toxicol In Vitro 2019 10.1016/j.tiv.2019.104622 0 0 0 295 Humans|*Induced Pluripotent Stem Cells|*Cell Differentiation|Hematopoiesis|Hematopoietic Stem Cells|*Cell Adhesion|Cells, Cultured|Endothelial Cells|Transcription Factors|*Morphogenesis|Hematopoietic Stem Cell Transplantation 125 ETV2 31278282 Sci Rep 2019 PMC6611806 10.1038/s41598-019-45841-5 0 1 0 295 *Embryogenesis|Transcription Factor|YES1 protein, human|*Proto-Oncogene Proteins c-yes|Cell Differentiation|Cell Lineage|*Cell Proliferation|Gene Expression Regulation, Developmental|Endothelium|Mesoderm|Endothelial Cells|Signal Transduction|Transcriptional Networks 125 ETV2 31160487 Biosci. Rep. 2019 PMC6620384 10.1042/BSR20190513 3 2 0 295 *Pathological Angiogenesis|Signal Transduction|Receptors, Cell Surface|Cell Movement|Intercellular Signaling Peptides and Proteins|Nerve Tissue Proteins|*Morphogenesis|Transcription Factors 125 ETV7 31827722 Oncotarget 2019 PMC6887571 10.18632/oncotarget.27306 0 6 0 205 *Carcinoma, Squamous Cell|*Mouth Neoplasms|SERPINE1 protein, human|*Plasminogen Activator Inhibitor 1|*Signal Transduction|Receptor, Notch1|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Mutations 43 ETV7 31255737 Gene 2019 10.1016/j.gene.2019.143948 2 0 0 205 Mice|Animals|*Endothelial Cells|*Apo E|*RNA, Circular|MicroRNAs|Atherosclerosis|Cell Movement|Cell Proliferation|Apoptosis 43 ETV7 30777133 Arthritis Res. Ther. 2019 PMC6378708 10.1186/s13075-019-1836-8 0 0 0 205 Humans|*Lupus Erythematosus, Systemic|Antibodies, Antiphospholipid|Antiphospholipid Syndrome|Antibodies, Antinuclear|Sjogren's Syndrome|Autoantibodies 43 FADS3 31862735 J. 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Genet. 2019 PMC6859434 10.1093/hmg/ddz161 1 0 0 110 Adult|Humans|Child|*Genome-Wide Association Study|*Pediatric Obesity|Bayes Theorem|Single Nucleotide Polymorphisms|Body Mass Index|Genetic Predisposition to Disease|Genetic Loci|Linkage Disequilibrium|Asian|European Continental Ancestry Group|Ethnicity|Case-Control Studies 91 FAIM2 31354816 Int J Endocrinol 2019 PMC6634012 10.1155/2019/4764751 1 1 0 110 Adult|Child|Humans|Child, Preschool|Adolescent|*Adipokines|Genome-Wide Association Study|Case-Control Studies|Mexico|*Obesity|Body Mass Index|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Alleles|Genotype|Membrane Proteins 91 FAIM2 31211943 Exp. 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Sci. 2019 10.1042/CS20180814 3 7 0 110 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Hep G2 Cells|Cell Movement|Cell Line, Tumor|Apoptosis|Signal Transduction|Disease Progression 91 FAIM3 30709812 Clin. Chem. 2019 10.1373/clinchem.2018.294819 0 0 0 72 Hemorrhagic Fever Virus, Crimean-Congo|Hemorrhagic Fever, Crimean|Immunoglobulin M|Antibodies, Viral|Enzyme-Linked Immunosorbent Assay|Immunoglobulin G|Sensitivity and Specificity|*Immunoglobulin-like Domain 23 farp1 31832114 EPMA J 2019 PMC6882982 10.1007/s13167-019-00187-w 1 0 0 105 Humans|*Pituitary Neoplasms|*Proteomics|*Follicle Stimulating Hormone|*Prognosis|Adenoma 26 farp1 31813151 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.12.016 0 0 0 105 Child|Humans|*Chromosome Deletion|*Chromosome Disorders|*Genetic Testing|Abnormalities, Multiple|Karyotyping|Chromosome Banding|Mental Retardation|Phenotype|*Chromosome Structures 26 farp1 31021836 Am J Dermatopathol 2019 10.1097/DAD.0000000000001426 0 0 0 105 Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Cell Proliferation|*Signal Transduction|*MAP Kinase Signaling System|Neoplasm Invasiveness|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Apoptosis|Phosphorylation|Biomarkers, Tumor 26 FASTKD2 31692063 J. 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Oncol. 2019 10.32471/exp-oncology.2312-8852.vol-41-no-4.13841 0 0 0 212 Humans|DNA Copy Number Variations|Leukovorin|5 Fluorouracil|Oxaliplatin|Colorectal Cancer|Cetuximab|Organoplatinum Compounds|Antineoplastic Combined Chemotherapy Protocols|Disease-Free Survival|Antibodies, Monoclonal|ErbB Receptors|Antibodies, Monoclonal, Humanized|*Colonic Neoplasms|*Rectal Neoplasms|Mutation 123 fat4 31819496 Onco Targets Ther 2019 PMC6877412 10.2147/OTT.S216289 0 0 0 212 Humans|*Multiple Myeloma|*Mutations|Chromosome Aberrations|Translocation, Genetic|In Situ Hybridization, Fluorescence|Prognosis|*Chinese|China 123 fat4 31747096 Dev. Dyn. 2019 10.1002/dvdy.137 0 0 0 212 Signal Transduction|Phosphoproteins|Adaptor Proteins, Signal Transducing|Cell Cycle Proteins|Morphogenesis|Protein-Serine-Threonine Kinases|Cell Proliferation 123 fat4 31737111 J Cancer 2019 PMC6843883 10.7150/jca.30307 0 0 0 212 123 fat4 31731517 Molecules 2019 PMC6864528 10.3390/molecules24213851 1 0 0 212 Adaptor Proteins, Signal Transducing|Phosphoproteins|Signal Transduction|Protein-Serine-Threonine Kinases|Cell Proliferation|Cell Movement|Tumor Suppressor Proteins|Gene Expression Regulation, Neoplastic|Transcription Factors|Cell Line, Tumor|Stomach Neoplasms|Phosphorylation|Xenograft Model Antitumor Assays|*Oils, Volatile|China 123 fat4 31633297 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61392 0 0 0 212 Humans|Hennekam lymphangiectasia lymphedema syndrome|Lymphangiectasis, Intestinal|Craniofacial Abnormalities|Lymphedema|Homozygote|Genotype|Phenotype|Alleles|Mutation|Pedigree|*Syndrome|Calcium-Binding Proteins|ADAMTS3 protein, human|ADAMTS Proteins|Procollagen N-Endopeptidase|CCBE1 protein, human|Tumor Suppressor Proteins 123 fat4 31395065 BMC Cancer 2019 PMC6686555 10.1186/s12885-019-6002-9 2 0 0 212 Humans|*Carcinoma, Hepatocellular|*Hepatitis B virus|*Genes, p53|*Liver Neoplasms|Hepatitis B|Mutation|Tumor Suppressor Protein p53|beta Catenin|Oncogenes|*Genetic Profile|Genomics|TP53 protein, human|FAT4 protein, human|Cadherins|Tumor Suppressor Proteins 123 fat4 31358536 Development 2019 10.1242/dev.176776 0 1 0 212 Humans|Animals|Mice|*Osteogenesis|Van Maldergem Wetzburger Verloes syndrome|Hand Deformities, Congenital|Foot Deformities, Congenital|Craniofacial Abnormalities|Abnormalities, Multiple|*Cell Differentiation|Intellectual Disability|Signal Transduction|Cadherins|Adaptor Proteins, Signal Transducing|Phosphoproteins|Tumor Suppressor Proteins|Cell Cycle Proteins|Mutations|Joint Instability|DCHS1 protein, human|FAT4 protein, human 123 fat4 31341365 World J. 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Cancer 2019 PMC6461827 10.1186/s12943-019-1014-2 27 6 0 190 Humans|RNA, Long Noncoding|Zinc Finger E-box-Binding Homeobox 1|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Proliferation|HCT116 Cells|MicroRNAs|Cell Movement|Colorectal Neoplasms|Cell Line, Tumor 33 FCGBP 31737124 J Cancer 2019 PMC6843882 10.7150/jca.32267 3 0 0 24 *Transcriptome|*Colorectal Cancer|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Signal Transduction 63 FCGBP 31658587 Int J Mol Sci 2019 PMC6834163 10.3390/ijms20205000 3 0 0 24 Humans|*Saliva|Proteomics|TFF3 Peptide|Trefoil Factor-2|Mucins|Peptides|*Dimerization|Blotting, Western|Mucus|Muscle Proteins|Immunoglobulin G|TFF3 protein, human|FCGBP protein, human|Cell Adhesion Molecules 63 FCGBP 31544986 Mol. Reprod. Dev. 2019 10.1002/mrd.23273 0 0 0 24 Animals|*Anguilla|Japan|Molecular Sequence Annotation|Genome|Transcriptome|Messenger RNA|Databases, Genetic|Gene Expression Regulation, Developmental 63 FCGBP 31268166 Int. J. Oncol. 2019 PMC6615923 10.3892/ijo.2019.4833 0 1 0 24 Humans|*Computational Biology|*Proteomics|*Transcriptome|*Colorectal Cancer|Gene Ontology|Prognosis|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Databases, Genetic|Protein Interaction Mapping|*Colonic Neoplasms|Signal Transduction 63 FCGBP 30868060 FEBS Open Bio 2019 PMC6396159 10.1002/2211-5463.12592 2 0 0 24 *Osteosarcoma|Bone Neoplasms|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Gene Ontology|Databases, Genetic|Protein Interaction Maps|Signal Transduction 63 FCGBP 30636330 Equine Vet. J. 2019 10.1111/evj.13068 0 0 0 24 Horses|Animals|*Equine Disease|*Gastric Disease|*Stomach|Gastroscopy|Physical Conditioning, Animal|*Mass Spectrometry|*Electrophoresis|*Serum Markers|Carcinoma, Squamous Cell 63 FCGRT 31209240 Sci Rep 2019 PMC6572836 10.1038/s41598-019-45203-1 2 5 0 1208 Humans|*DNA Methylation|Cell Line, Tumor|Transcription Factors|DNA-Binding Proteins|Receptors, Fc|Histocompatibility Antigens Class I|Promoter Regions, Genetic|*Liver|Base Sequence|Polymorphism, Genetic|Chromatin Immunoprecipitation|*Myocardium|ZBTB7A protein, human 45 FCGRT 31104841 Cell 2019 PMC7111318 10.1016/j.cell.2019.04.035 6 0 0 1208 Humans|Fc receptor, neonatal|Cryoelectron Microscopy|*Echovirus|*Fc Receptor|*Histocompatibility Antigens Class I|Enterovirus Infections|Enterovirus|Virus Uncoating|Capsid|Virus Particles|Capsid Proteins|Virus Entry|CD55 Antigens|Models, Molecular 45 FCRL1 31819081 Sci Rep 2019 PMC6901455 10.1038/s41598-019-54612-1 0 0 0 2 Humans|*Gene-Environment Interaction|Case-Control Studies|*Sarcoidosis|Genetic Susceptibility|Polymorphism, Single Nucleotide|HLA-DRB1 Chains|Sarcoidosis, Pulmonary|Gene Frequency|Genotypes|Phenotypes|*Smoking|*Tobacco Smoking|Syndrome|Genomics|Logistic Regression|Sweden|FCRL1 protein, human|Membrane Proteins 34 FCRL1 31798301 Biomark Insights 2019 PMC6864034 10.1177/1177271919882351 0 6 0 2 Humans|*Fc Receptor|B Cells|FCRL1 protein, human|Membrane Proteins|*Leukocyte Disorders|Immunotherapy 34 FCRL1 31640787 Hum. Genomics 2019 PMC6805350 10.1186/s40246-019-0236-0 0 2 0 2 SeSAME syndrome|*Intellectual Disability|*Hearing Loss, Sensorineural|*Seizures|Potassium Channels, Inwardly Rectifying|Phenotypes|Mutation|*Water-Electrolyte Imbalance|Syndrome|*Acid-Base Imbalance|Electrolytes 34 FCRL1 31467839 Leuk Res Rep 2019 PMC6710560 10.1016/j.lrr.2019.100181 0 0 0 2 Humans|Adult|*Leukemia, Lymphocytic, Chronic, B-Cell|*Leukemia, Hairy Cell|*Prognosis|Lymphoma, Non-Hodgkin|Mantle Cell Lymphoma|B-Lymphocytes|Flow Cytometry|Immunotherapy|Receptors, Fc|FCRL1 protein, human|Membrane Proteins 34 FCRL1 31328160 Sci Adv 2019 PMC6637015 10.1126/sciadv.aaw0315 2 2 0 2 Receptors, Antigen, B-Cell|*Lymphocyte Activation|B-Lymphocytes|Signal Transduction|*Genes, abl|Phosphorylation|src Homology Domains|Receptors, IgG|Carrier Proteins|Cytoplasm 34 FCRL1 30877410 Clin. Exp. Med. 2019 10.1007/s10238-019-00551-0 1 0 0 2 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Homozygote|*Down-Regulation|Ribonucleoprotein, U2 Small Nuclear|FCRL5 protein, human|*Fc Receptor|13q deletion syndrome|Chromosome Deletion|Mutation|Prognosis|RNA Splicing Factors|FCRL2 protein, human|Receptors, Cell Surface|Receptor, Notch1|Phosphoproteins|Translocation, Genetic|Sequencing, Next-Generation|Genes, Regulator 34 FER1L4 31694750 Clin. Exp. Rheumatol. 2019 0 4 0 42 *RNA, Long Noncoding|Synoviocytes|*Rheumatoid Arthritis|Fibroblast|Cell Proliferation|Cells, Cultured 38 FER1L4 31681595 Front Oncol 2019 PMC6803554 10.3389/fonc.2019.01059 1 0 0 42 38 FER1L4 31527170 Clin. Cancer Res. 2019 PMC6911634 10.1158/1078-0432.CCR-19-0740 2 0 0 42 *Genetic Markers|*Esophageal Cancer|DNA Methylation|Biomarkers, Tumor|Early Detection of Cancer 38 FER1L4 31473323 Gene 2019 10.1016/j.gene.2019.144093 5 4 0 42 *RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Osteosarcoma|*Apoptosis|RNA, Micro|Bone Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|Tumorigenesis 38 FER1L4 31443490 Cells 2019 PMC6770723 10.3390/cells8090954 1 2 0 42 Animals|Humans|Endothelial Cells|OTOF protein, human|Membrane Proteins|Dysferlin|Muscle Proteins|Calcium-Binding Proteins|Cell Membrane|*Membrane|Cell Proliferation 38 FER1L4 31332783 J. Cell. Physiol. 2019 10.1002/jcp.29098 2 0 0 42 Humans|*RNA, Long Noncoding|*Tumorigenesis|*Oncogenes|Gene Expression Regulation, Neoplastic|Prognosis|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Apoptosis 38 FER1L4 31323382 Clin. Gastroenterol. Hepatol. 2019 PMC6984349 10.1016/j.cgh.2019.07.017 1 0 0 42 Humans|*Pancreatic Juice|*B-DNA|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Carcinoma, Papillary|Methylations, DNA|Pancreas|Biomarkers, Tumor 38 FER1L4 31115514 Mol Med Rep 2019 PMC6579969 10.3892/mmr.2019.10219 5 6 0 42 *RNA, Long Noncoding|*Phosphatidylinositol 3-Kinases|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Cell Proliferation|*Lung Cancer|*Signal Transduction|Cell Lines, A549|Cell Migration|Carcinoma, Non-Small-Cell Lung|Gene Expression Regulation, Neoplastic|*Phosphatidylinositols|Cell Line, Tumor|MicroRNAs|Apoptosis|Tumorigenesis|*Neoplastic Processes 38 FER1L4 31000382 Pathol. Res. 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Med. 2019 PMC6484322 10.1111/jcmm.14198 9 3 0 42 *Glioma|Long Non-Coding RNA|*Cell Cycle|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Cell Movement|Stomach Neoplasms|Apoptosis|Up-Regulation|*Cell Division|siRNA|Colon Cancer 38 FER1L4 30781521 Cancers (Basel) 2019 PMC6406952 10.3390/cancers11020234 16 39 0 42 Humans|Female|*RNA, Long Noncoding|Phosphatidylinositol 3-Kinases|*Endometrial Cancer|*Endometrium|Gene Expression Regulation, Neoplastic|Upregulation|Prognosis|STAT3 protein, human|STAT3 Transcription Factor|PTEN protein, human|PTEN Phosphohydrolase|Cell Line, Tumor|Oncogenesis|Cell Proliferation|Tumor Microenvironment|Signal Transduction|TDRG1 protein, human|Proteins 38 FERD3L 31672641 Neuroscience 2019 10.1016/j.neuroscience.2019.09.003 0 1 0 19 Animals|Chick Embryo|*Transcription Factors|*Dopaminergic Neurons|Mesencephalon|Neurogenesis|Basic Helix-Loop-Helix Transcription Factors|Hepatocyte Nuclear Factor 3-beta|Nerve Tissue Proteins|Neural Tube|Cell Differentiation|Gene Expression Regulation, Developmental|Dopamine|Tyrosine Hydroxylase|Stem Cells|Transcriptional Networks|Spinal Cord 21 FERD3L 30919159 Neurogenetics 2019 10.1007/s10048-019-00569-2 0 1 0 19 Humans|*Intracranial Aneurysm|HDAC9 protein, human|*Histone Deacetylase|TWIST1 protein, human|*Twist-Related Protein 1|*Repressor Proteins|*Nuclear Proteins|*Genotype|Plaques, Atherosclerotic|Carotid Artery Diseases|Transcription Factor|Alleles|Genetic Predisposition to Disease|Gene Expression|Gene Expression Regulation|Polymorphism, Single Nucleotide 21 FERD3L 30786922 Clin Epigenetics 2019 PMC6381754 10.1186/s13148-019-0626-0 2 7 0 19 Humans|*Neoadjuvant Therapy|*Triple-Negative Breast Cancer|Taxoids|Antineoplastic Combined Chemotherapy Protocols|Docetaxel|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Cyclophosphamide|*Epigenetic|Epigenesis, Genetic 21 FERMT1 31409848 Sci Rep 2019 PMC6692320 10.1038/s41598-019-48089-1 1 0 0 210 *Osteogenesis|*Transcriptome|*Adipocytes|Cell Differentiation|*Transcriptome Profiling|Mesenchymal Stem Cells|Adipose Tissue|*Sequencing, RNA|Adipogenesis|*Base Sequence|Extracellular Matrix|Lineages, Cell|Cells, Stromal|Transductions, Signal|Cells, Cultured|Gene Ontology|*Whole Exome Sequencing 123 FERMT1 31340837 Orphanet J Rare Dis 2019 PMC6657209 10.1186/s13023-019-1158-6 2 0 0 210 Adult|Humans|Poikiloderma of Kindler|Retrospective Studies|*Epidermolysis Bullosa|*Photosensitivity Disorders|*Blister|*Periodontal Diseases|Neoplasm Proteins|Mutations|Membrane Proteins|Skin|Squamous Cell Carcinoma|Atrophy|Skin Neoplasms|FERMT1 protein, human 123 FERMT1 31260568 Exp. 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Genet. 2019 10.1111/cge.13555 0 0 0 210 Humans|Brazil|Poikiloderma of Kindler|*Epidermolysis Bullosa|Junctional Epidermolysis Bullosa|Bullosa, Dystrophic Epidermolysis|Epidermolysis Bullosa Simplex|Blister|Mutations|Sequencing, Next-Generation|Periodontal Diseases|Photosensitivity Disorders|FERMT1 protein, human|Membrane Proteins|Neoplasm Proteins|COL7A1 protein, human|Collagen Type VII 123 FERMT1 30875130 Dev. Dyn. 2019 10.1002/dvdy.26 0 1 0 210 Animals|*Odontogenesis|Transcription Factor|*Vertebrate|*Signal Transduction|Trans-Activators|Homeodomain Proteins|Mesoderm|Tooth|Gene Expression Regulation, Developmental|Phosphoproteins|Biological Evolution|Epithelium|Gene Expression 123 FERMT1 30858505 J. Hum. Genet. 2019 10.1038/s10038-019-0584-6 3 0 0 210 Humans|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|MicroRNAs|*Oncogenes|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Oncogenesis|Cell Movement|Prognosis|Cell Line, Tumor|Downregulation|Sequencing, RNA|FERMT1 protein, human|Membrane Proteins|Neoplasm Proteins|EPS8 protein, human|Adaptor Proteins, Signal Transducing 123 fes1 31806703 J. Biol. Chem. 2019 PMC6956543 10.1074/jbc.RA119.010125 0 0 0 198 *Saccharomyces cerevisiae|*Methionine|*HSP70 Heat-Shock Proteins|*Racemethionine|Saccharomyces cerevisiae Proteins|*Cytosol|*Redox|Molecular Chaperones|*Yeast, Dried|Methionine Sulfoxide Reductases|*Guanine Nucleotide Exchange Factors|*Cytoplasm|Mitochondria|Cysteine|*Nucleotides|Oxidative Stress|FES1 protein, S cerevisiae|Intracellular Signaling Peptides and Proteins 35 fes1 31789509 Environ. Sci. Technol. 2019 10.1021/acs.est.9b06393 0 0 0 198 *Mercury|ferrous sulfide|*Temperature|Coal|Power Plants|*Ferrous Compounds|Gases|Air Pollutants|Adsorption|Magnetic 35 fes1 31428776 Nucleic Acids Res. 2019 PMC6821268 10.1093/nar/gkz722 0 2 0 198 *Proteostasis|polyglutamine|*Ribonuclease|HTT protein, human|*Huntingtin Protein|*Peptides|HSP70 Heat-Shock Proteins|Saccharomyces cerevisiae Proteins|HSP40 Heat-Shock Proteins|Molecular Chaperones|Saccharomyces cerevisiae|Heat-Shock Proteins|Protein Folding|Huntington Disease|Heat Shock|RNA Exosome|*Gene Expression Regulation|Protein Binding 35 fes1 31242183 PLoS Genet. 2019 PMC6615629 10.1371/journal.pgen.1008219 2 3 0 198 *HSP70 Heat-Shock Proteins|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|*Guanine Nucleotide Exchange Factors|*Cell Wall|Prions|*Nucleotides|Heat-Shock Proteins|Intracellular Signaling Peptides and Proteins|Protein Folding|Adenosine Triphosphatases|3'-(1-butylphosphoryl)adenosine|*Gluconeogenesis|SLT2 protein, S cerevisiae|Mitogen-Activated Protein Kinases|FES1 protein, S cerevisiae 35 fes1 30796711 Plant Mol. Biol. 2019 10.1007/s11103-019-00844-8 0 1 0 198 *Thermotolerance|Arabidopsis thaliana|Arabidopsis Proteins|Stress, Heat|Gene Expression Regulation, Plant|Heat-Shock Proteins|Seedlings|Heat Shock Transcription Factors|Calmodulin|Transcription Factors|Heat|Molecular Chaperones|DNA-Binding Proteins|Signal Transduction|Cell Nucleus|HSP70 Heat-Shock Proteins|Protein Binding|BAG6 protein, Arabidopsis 35 FEZF1 31812516 Neuron 2019 PMC7007373 10.1016/j.neuron.2019.11.002 1 3 0 89 Amacrine Cells|*Interneurons|Retina|Gene Expression Regulation, Developmental|Repressor Proteins|Neurogenesis 65 FEZF1 31785996 Pathol. Res. Pract. 2019 10.1016/j.prp.2019.152757 1 0 0 89 *Stomach Neoplasms|Long Non-Coding RNA|Gene Expression Regulation, Neoplastic|RNA, Antisense|Repressor Proteins|Transcription Factors|Biomarkers, Tumor 65 FEZF1 31651322 BMC Med Genomics 2019 PMC6813133 10.1186/s12920-019-0593-5 0 0 0 89 *Attention Deficit Disorder with Hyperactivity|Genome-Wide Association Study|Genetic Predisposition to Disease|Study, Genetic Association|Polymorphism, Single Nucleotide|*Genetic Testing|Linkage Disequilibrium|Genotype 65 FEZF1 31579094 Oncol Lett 2019 PMC6757264 10.3892/ol.2019.10744 0 0 0 89 Humans|*lncRNA|*RNA, Anti-Sense|*Pseudogene|*Carcinoma, Non-Small-Cell Lung|Lung Cancer|*Prognosis|*Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Kaplan-Meier Analysis|Gene Expression Profiling|Signal Transduction|Transcription Factors|*Pulmonary Surfactants|Survival Analysis|*Surface-Active Agents|GATA6 protein, human|GATA6 Transcription Factor 65 FEZF1 31550856 Zhonghua Zhong Liu Za Zhi 2019 10.3760/cma.j.issn.0253-3766.2019.09.005 0 3 0 89 65 FEZF1 31378890 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201908_18534 0 0 0 89 *Carcinoma, Squamous Cell|*RNA, Long Noncoding|*Mouth Neoplasms|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Transcription Factors|Cell Line, Tumor|Repressor Proteins|MicroRNAs 65 FEZF1 31298365 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201906_18176 1 1 0 89 Humans|Male|*RNA, Long Noncoding|*Cell Proliferation|*Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Movement|Transcription Factors|Repressor Proteins|*Neoplastic Processes|*Prostate Cancer|Cell Line, Tumor 65 FEZF1 31281667 J Ophthalmol 2019 PMC6594282 10.1155/2019/4736203 0 8 0 89 *RNA, Long Noncoding|RNA, Anti-Sense|Cell Movement|Cell Proliferation|Epithelial-Mesenchymal Transition|Transcription Factors|Epithelial Cells|Gene Expression Regulation, Neoplastic|Repressor Proteins|Capsule Opacification 65 FEZF1 31276636 Clin. Chim. Acta 2019 10.1016/j.cca.2019.07.004 3 0 0 89 Humans|*RNA, Long Noncoding|*Zinc|Cellular Proliferation|RNA, Antisense|Hepatocellular Carcinoma|Gene Expression Regulation, Neoplastic|Carcinogenesis|Cell Movement|Transcription Factors|Repressor Proteins|Colorectal Cancer|Stomach Neoplasms|Liver Neoplasms 65 FEZF2 31261375 PLoS ONE 2019 PMC6602790 10.1371/journal.pone.0218858 2 0 0 183 Mice|Animals|Humans|*Transcriptome|Central Tolerance|Antigen Presentation|Dendritic Cells|Autoantigens|Epithelial Cells|T-Lymphocytes, Regulatory|Autoimmunity|Transcription Factors|Gene Expression Regulation|Mice, Inbred C57BL|DEAF1 protein, human|Nuclear Proteins|Deaf1 protein, mouse 109 FEZF2 31185198 Exp. Neurol. 2019 10.1016/j.expneurol.2019.112970 0 0 0 183 Animals|Mice|*Motor Cortex|*Hemiplegia|reelin protein|*Cell Adhesion Molecules, Neuronal|*Extracellular Matrix Proteins|*Serine Endopeptidases|*Nerve Tissue Proteins|*Motoneuron|Signal Transduction|Cell Movement|Cell Differentiation|VLDL receptor|Receptors, LDL|*Cell Transplantation|Phosphorylation|reelin receptor|Receptors, Cell Surface|Integrins 109 FEZF2 31024003 Cell Death Dis 2019 PMC6484078 10.1038/s41419-019-1578-1 2 0 0 183 Animals|APEX1 protein, human|*DNA-(Apurinic or Apyrimidinic Site) Lyase|*DNA Repair|oxoguanine glycosylase 1, human|DNA Glycosylases|*Oxidative Stress|DNA Polymerase beta|DNA Damage|TP53 protein, human|Tumor Suppressor Protein p53|8-hydroxyguanine|Guanine|Reactive Oxygen Species|Transcription Factors|Gene Expression Regulation|DNA|Zebrafish|Brain 109 FEZF2 31008523 Ann. N. Y. Acad. Sci. 2019 PMC6899491 10.1111/nyas.14089 1 1 0 183 Animals|Self Tolerance|Immune Tolerance|Autoimmunity|*Neurosecretory Systems|*Vertebrate|*Peptides|Major Histocompatibility Complex|Antigens 109 FEZF2 30972448 Osteoporos Int 2019 10.1007/s00198-019-04959-y 0 0 0 183 *RNA, Long Noncoding|*Parathyroid Neoplasms|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Adenoma|Gene Expression Regulation, Neoplastic|Parathyroid Glands|RNA, Messenger 109 FEZF2 30919954 J. Comp. Neurol. 2019 PMC6879308 10.1002/cne.24688 1 0 0 183 Animals|Finches|Amygdala|Vocalization, Animal|Neural Pathways|Prosencephalon 109 FGL1 31841754 Int. Immunopharmacol. 2019 10.1016/j.intimp.2019.106113 0 0 0 118 Humans|*T Cells|*Programmed Cell Death 1 Receptor|Lymphocytes, Tumor-Infiltrating|B7-H1 Antigen|Triple Negative Breast Neoplasms|Antineoplastic Agents, Immunological|Antineoplastic Combined Chemotherapy Protocols|Tumor Microenvironment|Biomarkers, Tumor 50 FGL1 31762715 Dose Response 2019 PMC6851613 10.1177/1559325819886766 0 0 0 118 Animals|Mice|*RNA, Long Noncoding|*Messenger RNA|*Transcription Factors|*Stomach|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Downregulation|Upregulation|Gastric Mucosa|*Radiation Injury|Ionizing Radiation|*Stomach Diseases 50 FGL1 31489941 Cells 2019 PMC6770824 10.3390/cells8091042 0 3 0 118 Humans|Mice|Animals|*Chemical and Drug Induced Liver Injury, Chronic|*Liver|Hepatocytes|Hepatocellular Carcinoma|*Biomarkers|Ionizing Radiation|Radiation Injuries, Experimental|Lung|*Plasma|Radiation Exposure|Fibrinogen|Upregulation|Oxidative Stress|Liver Neoplasms 50 FGL1 31322182 Int. 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Oncol. 2019 10.3892/ijo.2019.4838 0 3 0 118 Humans|*Lung Adenocarcinoma|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Lung|Adenocarcinoma|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Migration|Protein-Serine-Threonine Kinases|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Immunohistochemistry|Biomarkers, Tumor|Signal Transduction|*Liver|Mutation|*Neovascularization, Pathologic|*Liver Neoplasms 50 FILIP1 31465999 iScience 2019 PMC6718828 10.1016/j.isci.2019.08.016 2 2 0 40 Humans|Animals|*Interferon-alpha|*Chiroptera|*B Virus|*Transcriptome|IFNL3 protein, human|Antiviral Agents|Interferon-beta|Immunity, Innate|Tetherin|Base Sequence 22 FILIP1L 31819893 Eye Vis (Lond) 2019 PMC6885317 10.1186/s40662-019-0164-z 1 0 0 87 Humans|*Keratoconus|*Age Related Macular Degeneration|Complement Factor B|Complement Factor H|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Gene Frequency|Genotype|Genotyping Techniques|Complement C3|Proteins|Case-Control Studies 44 FILIP1L 31038092 J. Dairy Res. 2019 10.1017/S0022029919000232 0 0 0 87 Cattle|Animals|Female|*Phospholipase B|*Phospholipase|Lactation|*Cells, Epithelial|Mastitis, Bovine|Mammary Glands, Animal|Lipopolysaccharides|*Gene Expression|Cytokines|Cells, Cultured|Inflammation|*Cell Count|Apoptosis 44 FILIP1L 30651325 J. Neurosci. 2019 PMC6507086 10.1523/JNEUROSCI.1631-18.2018 2 1 0 87 Mice|Animals|*Chronic Pain|*RNA Splicing|AGO2 protein, human|*Argonaute Proteins|miRNA|RNA, Messenger|Spinal Cord|Inflammation|RNAs, Circular|Freund's Adjuvant 44 FJX1 31236144 Dis. Markers 2019 PMC6545767 10.1155/2019/3857853 0 3 0 72 *Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|*Oncogenes|Carcinoma|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Oncogenesis|Cell Line, Tumor|Biomarkers, Tumor|Up-Regulation|Signal Transduction|China 26 FJX1 31038742 J. Pathol. 2019 PMC6772084 10.1002/path.5286 1 0 0 72 Mice|Animals|*Polycystic Kidney, Autosomal Dominant|TRPP Cation Channels|*Kidneys|Potter Type III Polycystic Kidney Disease|Polycystic Kidney Diseases|Mice, Knockout|*Failure, Renal|Cell Polarity|Disease Models, Animal|Signal Transduction|Cell Proliferation|Phenotype|Disease Progression|Fibrosis|Great Britain|Ireland 26 FJX1 30853441 Dev. Cell 2019 PMC6766079 10.1016/j.devcel.2019.02.004 2 5 0 72 Humans|Mice|Animals|*Signal Transduction|*Organogenesis|Glial Cell Line-Derived Neurotrophic Factor Receptors|Kidney|Proto-Oncogene Proteins c-ret|Ureter|Glial Cell Line-Derived Neurotrophic Factor|Kidney Diseases|Gene Expression Regulation, Developmental|Cell Proliferation|RET protein, human|FAT4 protein, human|Cadherins|Tumor Suppressor Proteins|Fat4 protein, mouse 26 FJX1 30691798 J. Surg. Res. 2019 10.1016/j.jss.2018.09.053 0 0 0 72 Humans|*RNA, Long Noncoding|*miRNA|*mRNA|*Prognosis|*Colonic Neoplasms|*Adenocarcinoma|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Computational Biology|Kaplan-Meier Estimate|Colon 26 FKBP10 31868996 Kaohsiung J. Med. Sci. 2019 10.1002/kjm2.12174 0 0 0 126 Humans|*Stomach Neoplasms|*Phosphatidylinositol 3-Kinases|*Cell Proliferation|*Signal Transduction|Prognosis|Proto-Oncogene Proteins c-akt|Cell Movement|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Up-Regulation|Survival Rate|*Adenocarcinoma|Stomach|FKBP10 protein, human|Tacrolimus Binding Proteins 100 FKBP10 31844829 JBMR Plus 2019 PMC6894729 10.1002/jbm4.10241 0 0 0 126 Humans|Male|Female|Mice|Animals|Genome-Wide Association Study|*Femur|*Tibia|Bone Mineral Density|Bone|Quantitative Trait Loci|Phenotype|Xray Computed Tomography|*Dissection 100 FKBP10 31715670 Zhonghua Yi Xue Za Zhi 2019 10.3760/cma.j.issn.0376-2491.2019.42.011 0 0 0 126 100 FKBP10 31472299 Bone 2019 PMC6945817 10.1016/j.bone.2019.115047 0 1 0 126 Child|Humans|Female|Bruck syndrome 1|Bruck syndrome 2|*Osteogenesis Imperfecta|*Arthrogryposis|*Musculoskeletal Abnormalities|Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase|*Contracture|Genes, Recessive|Phenotype|Type I Collagen|Mutation|Bone Density|Fractures, Bone|*Joint Dislocations|Bone Formation|Hydroxylation|Codon, Nonsense|Mutation, Missense 100 FKBP10 31429852 Genet. Mol. Biol. 2019 PMC6726155 10.1590/1678-4685-GMB-2018-0043 0 0 0 126 Humans|*Osteogenesis Imperfecta|Genes, Recessive|Mutation|Collagen Type I|Genotype|Brazil|FKBP10 protein, human|Tacrolimus Binding Proteins 100 FKBP10 31233188 Oncol. Rep. 2019 PMC6609316 10.3892/or.2019.7195 0 0 0 126 Humans|*Prognosis|*Stomach Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Bioinformatics|Gene Expression Profiling|Upregulation|Disease-Free Survival|Kaplan-Meier Estimate|Cell Adhesion Molecules|FKBP10 protein, human|Tacrolimus Binding Proteins 100 FKBP10 30993005 BDJ Open 2019 PMC6459848 10.1038/s41405-019-0014-z 0 0 0 126 *Osteogenesis Imperfecta|*Dentinogenesis Imperfecta|South Africa|*Genotype-Phenotype Correlation|Genotype|Dentin|Mutation 100 FKBP10 30715774 Hum. Mutat. 2019 10.1002/humu.23718 1 0 0 126 Humans|*Osteogenesis Imperfecta|*Phenotypes|*Genotype|Type I Collagen|Genotype-Phenotype Correlations|*Chinese|Mutation|DNA Mutational Analysis|High-Throughput Nucleotide Sequencing|Codon, Nonsense|FKBP10 protein, human|Tacrolimus Binding Proteins 100 FKBP11 31492921 Sci Rep 2019 PMC6731300 10.1038/s41598-019-49289-5 0 9 0 61 Humans|Mice|Animals|*Cell Survival|*Insulin-Secreting Cells|DDIT3 protein, human|Transcription Factor CHOP|*Transcription Factors|Endoplasmic Reticulum Stress|Endoplasmic Reticulum|Unfolded Protein Response|X-Box Binding Protein 1|Thapsigargin|DNA-Binding Proteins|Apoptosis|Upregulation|Cytokines|Cell Line|Oxidative Stress|Regulatory Factor X Transcription Factors 21 FKBP11 31177839 Circulation 2019 PMC6690809 10.1161/CIRCULATIONAHA.118.038924 4 3 0 61 XBP1 protein, human|*X-Box Binding Protein 1|MTOR protein, human|*TOR Serine-Threonine Kinases|Unfolded Protein Response|Cardiomegaly|*RNA Splicing|Myocytes, Cardiac|Signal Transduction|Up-Regulation|Cell Cycle 21 FKBP11 30830262 Diabetologia 2019 10.1007/s00125-019-4844-y 0 0 0 61 Humans|Mice|Animals|*Mice, Obese|Diabetes Mellitus, Type 2|*Insulin-Secreting Cells|Islets of Langerhans|Insulin Secretion|*Macrophage|Insulin|Obesity|Gene Expression 21 FLVCR2 31428131 Front Genet 2019 PMC6690020 10.3389/fgene.2019.00694 0 0 0 41 Animals|*DNA Methylation|hydrogen sulfite|*Macaca fascicularis|Epigenesis, Genetic|*RNA-Seq|*Sulfites|CpG Islands|*Sequencing, Whole Genome|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|*Whole Exome Sequencing|Promoter Regions, Genetic|Software|Gene Expression Regulation|*Gene Expression|*Biochemical Phenomena|*Brain 22 FLVCR2 31372684 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03258-3 3 0 0 41 Humans|Animals|*Leishmania major|*Heme b|*Parasites|*Membrane Transport Proteins|*Biological Transport|Cutaneous Leishmaniasis|*Porphyrins|Protozoan Proteins|Virulence|Amino Acid Sequence|FLVCR2 protein, human|Receptors, Virus 22 FLVCR2 30890858 Cancer Inform 2019 PMC6416685 10.1177/1176935119835522 3 0 0 41 Humans|Male|*Transcriptome|Canada|*Prostate Cancer|*Computational Biology|*Sequencing, Next-Generation|Gene Expression Profiling|Cancer Biomarkers|Prostate|Gene Expression Regulation, Neoplastic|Prognosis|Disease Progression|Machine Learning|FLVCR2 protein, human|Receptors, Virus|Membrane Transport Proteins|USP13 protein, human|Endopeptidases|GABPB1 protein, human 22 FLVCR2 30642591 Vet. Microbiol. 2019 10.1016/j.vetmic.2018.12.024 1 0 0 41 Cattle|Animals|*Urinary Bladder|*Urothelium|*Leukemia Virus, Feline|*Papillomavirus Infections|*Papillomaviridae|Bovine papillomavirus 1|*Urologic Neoplasms|Urinary Bladder Neoplasms|feline leukemia virus receptor|*Receptors, Virus|Cattle Diseases|Base Sequence|PCR|Carcinoma, Transitional Cell|Oncogene Proteins|*Nepovirus 22 FMN1 31874696 Enzyme Microb. Technol. 2019 10.1016/j.enzmictec.2019.109455 0 0 0 3571 *Metabolic Engineering|*Flavin-Adenine Dinucleotide|Flavin Mononucleotide|Riboflavin|*Eremothecium|Nucleotidyltransferases|*Promoter Regions, Genetic|Phosphotransferases (Alcohol Group Acceptor)|Escherichia coli 42 FMN2 31738400 Clin. Sci. 2019 10.1042/CS20190715 4 2 0 123 *Colorectal Cancer|*Signal Transduction|RNA, Micro|Gene Expression Regulation, Neoplastic|Cell Proliferation|Up-Regulation|Cell Line, Tumor|*Colonic Neoplasms|mRNA|RNAs, Circular 63 FMN2 31302686 Rheumatology (Oxford) 2019 10.1093/rheumatology/kez269 0 3 0 123 Humans|*Wnt Signaling Pathway|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Alleles|*Catenins|Asian Continental Ancestry Group|beta Catenin|Sjogren's Syndrome|Case-Control Studies 63 FNDC1 31850076 Front Genet 2019 PMC6901973 10.3389/fgene.2019.01230 1 0 0 16 Child|Humans|Genome-Wide Association Study|*Otitis Media|Microbiome|*Microbial Interactions|Bacteria|*Epistasis, Genetic 29 FNDC1 31737218 Am J Transl Res 2019 PMC6834492 0 4 0 16 Humans|Female|Rats|Animals|*Osteoporosis, Postmenopausal|*Mesenchymal Stem Cells|*Rutin|Osteoporosis|Bone Density|Osteogenesis|MTOR protein, human|TOR Serine-Threonine Kinases|Autophagy|Signal Transduction|Ovariectomy|Rats, Sprague-Dawley|X-Ray Microtomography|FNDC1 protein, human|Neoplasm Proteins 29 FNDC1 31530096 Technol. 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Treat. 2019 PMC6751529 10.1177/1533033819869928 0 0 0 16 *Stomach Neoplasms|Cell Migration|Neoplasm Invasiveness|Prognosis|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Stomach|RNA, Small Interfering 29 FNDC1 31310629 PLoS ONE 2019 PMC6634788 10.1371/journal.pone.0218989 1 0 0 16 Humans|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Prognosis|Carcinoma, Squamous Cell|Cancer, Tongue|Papillomavirus Infections|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|EPS8 protein, human|Adaptor Proteins, Signal Transducing|FNDC1 protein, human|Neoplasm Proteins|UBE2Q1 protein, human|Ubiquitin-Conjugating Enzymes|SLC4A1AP protein, human|Antiporters 29 FNDC1 31093274 Gastroenterol Res Pract 2019 PMC6481110 10.1155/2019/3784172 3 0 0 16 *Fibronectin Type III Domain|*Colorectal Cancer|*Inflammatory Bowel Disease|*Colonic Neoplasms|Intestinal Mucosa|*Fibronectin Type III Domain|*Colorectal Cancer|*Inflammatory Bowel Disease|*Colonic Neoplasms|Intestinal Mucosa 29 FNIP1 31676673 J. Immunol. 2019 PMC6864314 10.4049/jimmunol.1900395 0 2 0 189 Humans|*Mechanistic Target of Rapamycin Complex 1|*AMP-Activated Protein Kinases|*Estrone|protein kinase modulator|*Intracellular Signaling Peptides and Proteins|FLCN protein, human|Tumor Suppressor Proteins|Proto-Oncogene Proteins|TOR Serine-Threonine Kinases|*Homeostasis|Signal Transduction|Carrier Proteins|Autophagy|*Lymphocyte Activation|*Hematopoiesis|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|B-Lymphocytes|TFE3 protein, human 44 FNIP1 30699359 Cell Rep 2019 PMC6370319 10.1016/j.celrep.2019.01.018 6 34 0 189 *HSP90 Heat-Shock Proteins|*Molecular Chaperone|Phosphorylation|protein phosphatase 5|Nuclear Proteins|Phosphoprotein Phosphatases|Ubiquitination|Proteasome Endopeptidase Complex|Post-Translational Modifications|Protein Binding|Kinase|Acetylglucosamine 44 FNIP1 30627666 Sci Adv 2019 PMC6314648 10.1126/sciadv.aav0443 12 4 0 189 Humans|*Mitophagy|*Phosphorylation|parkin protein|*Ubiquitin-Protein Ligases|Protein Kinase|Ubiquitin|Transcription Factor TFIIIA|Mitochondrial Proteins|Autophagy|Mitochondria|Protein-Serine-Threonine Kinases|Membrane Proteins|HeLa Cells|Carrier Proteins|TBK1 protein, human 44 FOXD1 31795213 Cancers (Basel) 2019 PMC6966623 10.3390/cancers11121897 1 11 0 158 galectin-3, human|*Galectin 3|*Lung Cancer|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Movement|Forkhead Transcription Factors|Up-Regulation 191 FOXD1 31623827 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.10.080 0 0 0 158 Mice|Animals|*Mesangial Cells|*Kidney|*Glomerular Mesangium|Cell Lineage|Nephrons|Cell Differentiation|Embryonic Stem Cells|Cells, Stromal|Regeneration|Kidney Diseases|*B-Lymphocytes|Regenerative Medicine|Organogenesis 191 FOXD1 31602254 J Cancer 2019 PMC6775620 10.7150/jca.31191 3 2 0 158 *Down-Regulation|gemcitabine|*Drug Resistance, Neoplasm|*Carcinoma, Pancreatic Ductal|*Deoxycytidine|Pancreatic Carcinoma|*Pancreatic Cancer|miRNA|Cell Proliferation|Gene Expression Regulation, Neoplastic|RNA Interference|Cell Line, Tumor|3' Untranslated Regions|Cell Cycle|Apoptosis|Cell Movement|Up-Regulation|Prognosis 191 FOXD1 31405952 J. Am. Soc. Nephrol. 2019 PMC6727263 10.1681/ASN.2018070699 1 0 0 158 Mice|Animals|*Glomerular Mesangium|*Cyclooxygenase 2|*Organogenesis|Kidney Glomerulus|Podocytes|Mice, Knockout|Signal Transduction|Forkhead Transcription Factors|Phenotype|B-Lymphocytes 191 FOXD1 31405951 J. Am. Soc. Nephrol. 2019 PMC6727249 10.1681/ASN.2018111143 1 0 0 158 Humans|Mice|Animals|*Mesangial Cells|GATA3 protein, human|*GATA3 Transcription Factor|Kidney|Hypoparathyroidism|Cell Proliferation|Gene Expression Regulation|*Organogenesis|Disease Models, Animal 191 FOXD1 31395028 Mol. Med. 2019 PMC6688323 10.1186/s10020-019-0104-3 0 0 0 158 Humans|Infant, Newborn|Female|Pregnancy|Mice|Animals|*Pre-Eclampsia|*Intrauterine Growth Restriction|Placenta|Abortion, Habitual|Genetic Predisposition to Disease|*Mutations|Polymorphism, Single Nucleotide|*Infant, Small for Gestational Age|Implantation, Embryo|Case-Control Studies|Phenotypes|FOXD1 protein, human|Forkhead Transcription Factors|Foxd1 protein, mouse 191 FOXD1 31364375 Am. J. Physiol. Renal Physiol. 2019 PMC6766625 10.1152/ajprenal.00243.2019 0 1 0 158 Mice|Animals|NT5E protein, human|*5'-Nucleotidase|*GPI-Linked Proteins|Adenosine|Kidney|Fibrosis|Mice, Knockout|Pericytes|Signal Transduction|Acute Kidney Injury|Mice, Inbred C57BL|Epithelial Cells|Fibroblasts|Disease Models, Animal|Inflammation 191 FOXD1 31252264 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109133 3 1 0 158 Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|Sp1 protein, human|*Sp1 Transcription Factor|MicroRNAs|Neoplasm Invasiveness|Up-Regulation|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Tumorigenesis|Gene Knockdown Techniques|HeLa Cells|Oncogene|3' UTR|Disease Progression|FOXD1 protein, human 191 FOXD1 31102349 CNS Neurosci Ther 2019 PMC6930828 10.1111/cns.13152 3 2 0 158 *RNA, Long Noncoding|*Glioma|*Oncogenes|MicroRNAs|Gene Expression Regulation, Neoplastic|*Oncogenesis|Cell Proliferation|Brain Neoplasms|Cell Movement|Cell Line, Tumor|RNA, Small Interfering|*Biomarkers|Apoptosis|Disease Progression 191 FOXD1 31042081 Am. J. Physiol. Lung Cell Mol. Physiol. 2019 PMC6734386 10.1152/ajplung.00295.2018 0 1 0 158 Mice|Animals|*Renin|*Wnt Signaling Pathway|Vacuolar Proton-Translocating ATPases|Renin-Angiotensin System|*Organogenesis|*Catenins|Receptors, Cell Surface|Knockout Mouse 191 FOXD1 30969804 Am. J. Physiol. Renal Physiol. 2019 10.1152/ajprenal.00305.2018 0 0 0 158 Mice|Animals|*Kidney|Renin-Angiotensin System|Receptor, Angiotensin, Type 1|Renin|Angiotensin II|Signal Transduction|*Organogenesis 191 FOXE1 31846430 Endocr. Relat. Cancer 2019 PMC6993207 10.1530/ERC-19-0156 0 0 0 257 Humans|*Thyroid Gland|*Thyroid Cancer|Epithelial-Mesenchymal Transition|Promoter Regions, Genetic|Homeodomain Proteins|Zinc Finger E-box-Binding Homeobox 1|Cell Migration|Forkhead Transcription Factors|SNPs|Cell Line, Tumor|ZEB1 protein, human|FOXE1 protein, human 241 FOXE1 31751626 Mol. Cell. Endocrinol. 2019 10.1016/j.mce.2019.110638 2 0 0 257 Humans|Child|*Congenital Hypothyroidism|DUOX1|Iodide Peroxidase|Thyroid Hormones|Goiter|Receptors, Thyrotropin|Mutations|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Gland, Thyroid|Genes, Homeobox|Phenotype|*Folding, Protein|FOXE1 protein, human|Forkhead Transcription Factors|DUOX2 protein, human|DUOXA2 protein, human|Membrane Proteins 241 FOXE1 31589286 Brief. Bioinformatics 2019 10.1093/bib/bbz082 2 5 0 257 Humans|Mice|Animals|*Gene Regulatory Networks|*Cleft Palate|*MicroRNAs|Gene Expression Profiling|Computational Biology|Cell Proliferation|Palate|Transcription Factors|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Transforming Growth Factor beta|FOXE1 protein, human|Forkhead Transcription Factors 241 FOXE1 31582725 Cell Death Dis 2019 PMC6776533 10.1038/s41419-019-1975-5 1 6 0 257 Humans|Mice|Animals|*HMGA1a Protein|*Thyroid Gland|*Perinatal Death|*Respiratory Distress Syndrome, Adult|HIPK2 protein, human|Serine Threonine Kinase|Carrier Proteins|Phosphorylation|Transcription Factors|*Thyroid Dysgenesis|Protein Binding|DNA|*Thyroid Diseases|Mice, Knockout|FOXE1 protein, human|Forkhead Transcription Factors 241 FOXE1 31564061 Oral Dis 2019 10.1111/odi.13204 0 1 0 257 *Cleft Palate|*Single Nucleotide Polymorphisms|Cleft Lip|Genetic Predisposition to Disease|Alleles|Transcription Factors|Genotype|Case-Control Studies|Brazil 241 FOXE1 31558162 J Transl Med 2019 PMC6764142 10.1186/s12967-019-2068-z 2 0 0 257 *Methylation|*Lung Adenocarcinoma|*Transcriptome Analysis|RNA, Long Noncoding|Prognosis|Adenocarcinoma|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Transcriptome|mRNA|Kaplan-Meier Estimate 241 FOXE1 31452441 Thyroid 2019 10.1089/thy.2018.0314 1 10 0 257 241 FOXE1 31345669 Int Orthod 2019 10.1016/j.ortho.2019.06.026 0 0 0 257 *Cleft Lip|Cleft Palate|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Alleles|Case-Control Studies|*Syndromes|Palate 241 FOXE1 31301652 Folia Med (Plovdiv) 2019 10.2478/folmed-2018-0078 0 0 0 257 *Thyroid Gland|*Thyroid Diseases|Receptors, Thyrotropin|Graves Disease|Thyroid Neoplasms|Genetic Predisposition to Disease 241 FOXE1 31247975 Genes (Basel) 2019 PMC6678600 10.3390/genes10070482 3 0 0 257 Humans|*Risk Factors|*Thyroid Cancer, Papillary|Thyroid Cancer|Carcinoma, Papillary|Cowden Syndrome|Familial Adenomatous Polyposis|Thyroid Gland|Genetic Predisposition to Disease|Gardner Syndrome|Carney Complex|Syndrome, Werner|*Germ Line 241 FOXE1 31186438 Sci Rep 2019 PMC6559957 10.1038/s41598-019-44600-w 0 0 0 257 Humans|Female|Pregnancy|Sheep|Animals|*lncRNA|*Hair Follicle|*Genome|mRNA|Transcriptome Profile|Gene Ontology|Gene Expression Profiling|Real-Time PCR, Quantitative|*Fetus|*Organogenesis|*Prenatal Care|FOXE1 protein, human|Forkhead Transcription Factors|DSG4 protein, human|Desmogleins 241 FOXE3 31884615 Adv. Exp. Med. Biol. 2019 10.1007/978-3-030-27378-1_36 0 0 0 58 Humans|*Anophthalmos|Microphthalmia|*Mutations|Homeodomain Proteins|Anterior segment mesenchymal dysgenesis|Eye Abnormalities|SOXB1 Transcription Factors|Transcription Factors|Mutation, Frame Shift|Homozygote|Phenotypes|Egypt|FOXE3 protein, human|Forkhead Transcription Factors|VSX2 protein, human|SOX2 protein, human 110 FOXE3 31831170 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.12.034 0 3 0 58 Humans|*Triple-Negative Breast Cancer|*Transcription Factor|*Oncogenesis|*Oncogenes|Cell Proliferation|Cell Cycle Arrest|Signal Transduction|Cell Line, Tumor|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|Gene Expression Regulation, Neoplastic|Docetaxel|Upregulation|FOXE3 protein, human|Forkhead Transcription Factors 110 FOXE3 31479653 Exp. Eye Res. 2019 PMC6867612 10.1016/j.exer.2019.107787 1 0 0 58 Humans|Mice|Cats|Animals|*Lens, Crystalline|Cataract|*Cell Line|Eye Proteins|Epithelial Cells|Genes, Homeobox|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Gene Expression|*Epithelium|RNA, Messenger|Cells, Cultured|Membrane Proteins|INPPL1 protein, human|Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|Inppl1 protein, mouse 110 FOXE3 31053165 Epigenetics Chromatin 2019 PMC6498704 10.1186/s13072-019-0272-y 2 0 0 58 *Chromatin|*Lens, Crystalline|Paired Box Transcription Factors|*Cell Differentiation|Homeodomain Proteins|Eye Proteins|Repressor Proteins|PAX6 Transcription Factor|Crystallins|DNA|Binding Sites|Gene Expression Regulation, Developmental|Proto-Oncogene Proteins c-maf|Promoter Regions, Genetic|Histone|Protein Binding 110 FOXE3 30991053 Exp. Eye Res. 2019 PMC6876282 10.1016/j.exer.2019.03.024 2 0 0 58 Mice|Animals|*Microphthalmos|*Histones|Lens, Crystalline|Crystallins|Eye Proteins|Homeodomain Proteins|*Mutation|Transcription Factors|Retina|Homozygotes|N-Ethyl-N-nitrosourea|Phenotype|Zebrafish 110 FOXE3 30736081 Klin Monbl Augenheilkd 2019 10.1055/a-0809-5523 0 0 0 58 Peters anomaly|*Eye Abnormalities|Anterior segment mesenchymal dysgenesis|Aniridia|Anterior Eye Segment|Transcription Factor PAX6|Homeodomain Proteins|Eye Diseases, Hereditary|Phenotype|Microphthalmia|Genotype|Mutation|Forkhead Transcription Factors|Corneal Opacity 110 FOXF1 31858528 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201912_19759 0 0 0 427 *Osteogenesis|*Mesenchymal Stem Cells|*Fracture Healing|Cell Differentiation|Osteoblasts|Bone Marrow Cells|Cells, Cultured|*Fractures, Closed|*Ultrasonic Therapy|Forkhead Transcription Factors 269 FOXF1 31813796 Dev. Cell 2019 10.1016/j.devcel.2019.11.003 0 1 0 427 Humans|Mice|Animals|*Hedgehog Proteins|Body Patterning|Signal Transduction|Gene Expression Regulation, Developmental|Morphogenesis|SOX2 protein, human|SOXB1 Transcription Factors|Mesenchyme|Transcription Factors|Endoderm|Trachea|*Endosome|Esophagus|Epithelium|Digestive System|NKX2-1 protein, human|Thyroid Nuclear Factor 1|FOXF1 protein, human 269 FOXF1 31760915 Biochemistry Mosc. 2019 10.1134/S0006297919110038 0 0 0 427 *Hydrolysis|Proton-Translocating ATPases|Paracoccus denitrificans|Adenosine Triphosphate|Kinetics|*Metabolic Clearance Rate 269 FOXF2 31858547 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201912_19782 1 0 0 209 *Carcinoma, Non-Small-Cell Lung|H19 long non-coding RNA|*RNA, Long Noncoding|*Lung Neoplasms|PTEN protein, human|*PTEN Phosphohydrolase|*Downregulation|A549 Cells|MicroRNAs|*Disease Progression|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 118 FOXF2 31741768 Oncoimmunology 2019 PMC6844300 10.1080/2162402X.2019.1665978 0 0 0 209 118 FOXF2 31710439 Clin. Lab. 2019 10.7754/Clin.Lab.2019.190133 0 0 0 209 *RNA, Long Noncoding|*Computational Biology|*Prognosis|*Rectal Cancer|Gene Regulatory Networks|MicroRNAs|RNA, Messenger|Gene Expression Regulation, Neoplastic|Gene Ontology|Biomarkers, Tumor|Colonic Neoplasms|Adenocarcinoma|Kaplan-Meier Estimate 118 FOXF2 31607140 Cleft Palate Craniofac. J. 2019 10.1177/1055665619880401 0 0 0 209 *Velopharyngeal Insufficiency|*Uvula|Palate, Soft|Pharynx|Cleft Palate|Speech Disorders|Surgical Flaps|*Nasopharyngeal Diseases|*Syndrome|Reoperation 118 FOXF2 31397443 Mol. Biol. (Mosk.) 2019 10.1134/S0026898419040189 1 1 0 209 Humans|Animals|*mRNA|*miRNAs|3' UTR|Binding Sites|5' UTR|Nucleotide Sequence|HOXA10 protein, human|Homeobox A10 Proteins|FOXF2 protein, human|Forkhead Transcription Factors|MIRN136 microRNA, human 118 FOXF2 31222004 Nat Commun 2019 PMC6586905 10.1038/s41467-019-10379-7 2 0 0 209 Humans|*Bone Neoplasms|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|MCF-7 Cells|Cell Movement|BMP4 protein, human|Bone Morphogenetic Protein 4|Cell Line, Tumor|Forkhead Transcription Factors|Signal Transduction|Cell Proliferation|noggin protein|Carrier Proteins|Transcription, Genetic|Promoter Regions, Genetic|FOXF2 protein, human 118 FOXF2 31131597 Balkan Med J 2019 PMC6636654 10.4274/balkanmedj.galenos.2019.2019.4.66 0 0 0 209 Humans|*Ear, Inner|Labyrinth Diseases|Deafness|Hearing Loss, Sensorineural|Hearing Loss|Tomography, X-Ray Computed 118 FOXF2 30987631 BMC Med Genomics 2019 PMC6466812 10.1186/s12920-019-0501-z 9 0 0 209 *Colorectal Cancer|CpG Islands|DNA Methylation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|*Transcription Factors|Promoter Regions, Genetic|*Genes, cdc|Gene Expression Profiling|*Colonic Neoplasms 118 FOXF2 30917284 J. Dent. Res. 2019 PMC6535918 10.1177/0022034519837245 1 0 0 209 Humans|Mice|Animals|*Uvula|Egypt|Palate, Soft|Velopharyngeal Insufficiency|Cleft Palate|*Nasopharyngeal Diseases|Forkhead Transcription Factors|Phenotype|FOXF2 protein, human 118 FOXF2 30807702 FASEB J. 2019 10.1096/fj.201801916R 2 0 0 209 Humans|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Forkhead Transcription Factors|Cell Line, Tumor|Cell Movement|Transcription, Genetic|Promoter Regions, Genetic|FOXF2 protein, human|FOXQ1 protein, human 118 FOXI3 31600545 J. Allergy Clin. Immunol. 2019 PMC6949372 10.1016/j.jaci.2019.09.020 1 0 0 37 Humans|*DiGeorge Syndrome|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Marfan Syndrome|*Craniosynostoses|*Chromosome 2|Forkhead Transcription Factors|Epithelial Cells|Mutations 30 FOXI3 31412026 PLoS Genet. 2019 PMC6709926 10.1371/journal.pgen.1008301 3 0 0 37 Humans|Mice|Animals|*DiGeorge Syndrome|*Endoderm|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Marfan Syndrome|T-Box Domain Proteins|*Craniosynostoses|Branchial Region|*Disease Models, Animal|Heterozygote|Parathyroid Glands|TBX1 protein, human|Foxi3 protein, human|Forkhead Transcription Factors|Tbx1 protein, mouse|Foxi3 protein, mouse 30 FOXI3 30927068 Hum. Genet. 2019 PMC6536473 10.1007/s00439-019-02005-9 3 0 0 37 Dogs|Humans|Female|Animals|Scotland|*Frameshift Mutation|*Alopecia|Sequencing, Whole Genome|Breeding|Dog Diseases|Exon|SGK3 protein, human|Protein-Serine-Threonine Kinases|Foxi3 protein, human|Forkhead Transcription Factors 30 FOXJ3 31771046 Cancer Biomark 2019 10.3233/CBM-190782 0 2 0 127 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|MicroRNAs|Cell Movement|Cell Proliferation|Down-Regulation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Neoplastic Processes|Lymphatic Metastasis|Prognosis|MIRN425 microRNA, human 21 FOXJ3 31373158 Am. J. Transplant. 2019 10.1111/ajt.15553 0 0 0 127 Humans|*Kidney Transplantation|*Transcriptome|Blood Group Incompatibility|Graft Rejection|ABO Blood-Group System|*Antibodies|Living Donors|Graft Survival|Biopsy|Retrospective Studies|Sequencing, RNA|*Anemia, Hemolytic, Autoimmune|*Transfusion Reaction|*Hematologic Tests|Gene Expression Profiling|FoxJ3 protein, human|Cell Cycle Proteins|Forkhead Transcription Factors 21 FOXJ3 30912256 Dev Neurobiol 2019 PMC6586502 10.1002/dneu.22676 1 0 0 127 Animals|*Hydra|*Neurogenesis|Stem Cells|Nervous System|Neurons|*Aging|Cell Differentiation|Gametogenesis|arginylphenylalaninamide|Neuropeptides|Epithelial Cells|Regeneration|Germ Cells|Hym-355 neuropeptide|Downregulation 21 FOXJ3 30720162 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201901_16867 0 2 0 127 Humans|Male|*Prostate Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|MIRN425 microRNA, human 21 FOXL1 31682594 PLoS Comput. Biol. 2019 PMC6855562 10.1371/journal.pcbi.1007460 0 0 0 224 Humans|Male|Neoplasm Recurrence, Local|Radiosensitivity|*Prostate Cancer|Network, Gene|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Cell Line, Tumor|MicroRNAs|Down-Regulation|Biomarkers, Tumor|RNA, Messenger|Signal Transduction|Gene Expression Profiles|siRNA|*Relapse|PAK7 protein, human|FOXL1 protein, human|Forkhead Transcription Factors 103 FOXL1 31311805 Development 2019 PMC6679369 10.1242/dev.175018 2 0 0 224 Animals|*Telocytes|Stem Cell Niche|Interstitial Cells of Cajal|Homeostasis 103 FOXL1 31289550 Oncol Lett 2019 PMC6540307 10.3892/ol.2019.10351 0 0 0 224 Adult|Humans|*Glioma|Prognosis|Brain Neoplasms|Kaplan-Meier Analysis|Gene Expression Regulation, Neoplastic|Immunohistochemistry|FOXL1 protein, human|Forkhead Transcription Factors 103 FOXL1 31036756 Clin. Sci. 2019 10.1042/CS20180845 6 4 0 224 Humans|*Hedgehog Proteins|*Tumor Microenvironment|SMO protein, human|Smoothened Receptor|Zinc Finger Protein GLI1|Signal Transduction|Patched Receptors|Pyridines|Transcription Factors|Cell Proliferation|Neoplasms|Genetic Testing 103 FOXL1 30971290 J. Exp. Clin. Cancer Res. 2019 PMC6458726 10.1186/s13046-019-1128-9 10 6 0 224 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Epithelial-Mesenchymal Transition|Hep G2 Cells|Cell Line, Tumor|Cell Movement 103 FOXL1 30965141 Cell Mol Gastroenterol Hepatol 2019 PMC6538877 10.1016/j.jcmgh.2019.04.001 3 0 0 224 *Stem Cell Niche|Hedgehog Proteins|*Telocytes|Progenitor Cells|Cell Self Renewal|Intestinal Mucosa|Wnt Signaling Pathway|Cell Differentiation|Colon|Cell Proliferation|Cell Division|Forkhead Transcription Factors 103 FOXL1 30809552 Biomed Res Int 2019 PMC6369469 10.1155/2019/9642589 1 0 0 224 Mice|Animals|*RNA, Long Noncoding|*Alzheimer Disease|*Lipopolysaccharides|Neurodegenerative Diseases|mRNA|Hippocampus|Disease Models, Animal 103 FOXL1 30683451 Differentiation 2019 10.1016/j.diff.2019.01.001 1 0 0 224 *Stem Cell Niche|Stem Cell|Wnt Proteins|Intestines|Intestinal Mucosa|Cell Differentiation|Wnt Signaling Pathway|Cell Self Renewal|Myofibroblasts|Telocytes|Cell Proliferation|Homeostasis|Epithelial Cells|Cells, Stromal|Acyltransferases 103 FOXL1 30606694 Comput Biol Chem 2019 10.1016/j.compbiolchem.2018.12.011 8 0 0 224 *Alzheimer Disease|MIRN124 microRNA, human|MicroRNAs|Transcriptome|Gene Expression Profiling|Gene Expression Regulation|Biomarkers|Computational Biology|Transcription Factors 103 FOXN2 30922331 Lipids Health Dis 2019 PMC6440132 10.1186/s12944-019-1023-6 1 1 0 138 Humans|Female|Mice|Animals|*Uterine Cervical Neoplasms|*Olive Oil|*Transcriptome Analysis|Protein Interaction Maps|Gene Regulatory Networks|Computational Biology|Transcriptome|Gene Expression Regulation, Neoplastic|Protein Interaction Mapping|Signal Transduction|*Diets|*Biological Phenomena 28 FOXN2 30720155 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201901_16860 6 4 0 138 Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Prognosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Wilms Tumor 1|Genes, Tumor Suppressor|Cell Line, Tumor|Apoptosis|Tumorigenesis|Disease Progression|Kidney Neoplasms|WT1 protein, human|WT1 Proteins 28 FOXN2 30655703 Cancer Manag Res 2019 PMC6324606 10.2147/CMAR.S176938 1 2 0 138 *Epithelial-Mesenchymal Transition|*Downregulation|Neoplasm Invasiveness|Snail Family Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Proliferation|Transcription Factors 28 FOXN4 31558434 Development 2019 PMC6826037 10.1242/dev.177428 10 0 0 65 Mice|Humans|Swine|Animals|*Cell Differentiation|*Sequencing, RNA|Respiratory Mucosa|Trachea|Goblet Cells|Epithelial Cells|Regeneration|Cells, Cultured|*Nose|Signal Transduction|*Base Sequence|*Whole Exome Sequencing|HES6 protein, human|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Hes6 protein, mouse 54 FOXN4 31430519 Gene 2019 10.1016/j.gene.2019.144057 1 5 0 65 *Signal Transduction|Receptors, Notch|*Cell Transformation, Neoplastic|Cell Line, Tumor|Membrane Proteins|Calcium-Binding Proteins|Cell Proliferation|Carcinogenesis 54 FOXP4 31815635 Mol. Cancer 2019 PMC6900861 10.1186/s12943-019-1110-3 1 1 0 147 FOXP4 protein, human|Forkhead Box Transcription Factors|*Neoplastic Processes|Repressor Proteins|T-Lymphocytes, Regulatory|Cancers|Biological Products 80 FOXP4 31801721 Nan Fang Yi Ke Da Xue Xue Bao 2019 PMC6867958 10.12122/j.issn.1673-4254.2019.10.19 0 0 0 147 Female|Pregnancy|Humans|*RNA, Long Noncoding|*Placenta Accreta|Gene Regulatory Networks|MicroRNAs|RNA, Messenger|Gene Expression Regulation, Neoplastic|Gene Ontology|Gene Expression Profiling|Transcriptome|Biomarkers, Tumor|Computational Biology|Kaplan-Meier Estimate 80 FOXP4 31695417 Onco Targets Ther 2019 PMC6718253 10.2147/OTT.S220923 2 0 0 147 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Up-Regulation|*Liver Neoplasms|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Ontology|Gene Expression Profiling|MicroRNAs|Protein Interaction Maps|Computational Biology|RNA, Messenger|*Transcriptional Activation 80 FOXP4 31646567 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201910_19148 1 4 0 147 *RNA, Long Noncoding|*Stomach Neoplasms|*Carcinogenesis|Enhancer of Zeste Homolog 2 Protein|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Histone Demethylases|*Carcinogens|Disease Progression 80 FOXP4 31641053 J. Neurosci. 2019 PMC6891055 10.1523/JNEUROSCI.1250-19.2019 1 0 0 147 Animals|Male|*Lentivirus|FOXP4 protein, human|*Forkhead Transcription Factors|Finches|Vocalization, Animal|Learning|Brain|Basal Ganglia|Neurons|Downregulation|Synaptic Transmission|RNA, Messenger 80 FOXP4 31500519 Technol. Cancer Res. Treat. 2019 PMC6737863 10.1177/1533033819874803 1 1 0 147 *Carcinoma, Squamous Cell|*Mouth Neoplasms|MicroRNAs|Cell Proliferation|FOXP4 protein, human|*Forkhead Transcription Factors|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Movement|3' Untranslated Regions|RNA Interference|Cell Line, Tumor|Down-Regulation 80 FOXP4 31312393 Am J Transl Res 2019 PMC6614621 0 3 0 147 Humans|*Sarcoma, Ewing|*RNA, Long Noncoding|*miRNA|*Neuroectodermal Tumors, Primitive, Peripheral|Proto-Oncogene Protein c-fli-1|Bone Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Line, Tumor|Oncogene Proteins, Fusion|Up-Regulation|SOX2 protein, human|SOXB1 Transcription Factors 80 FOXP4 31270953 J. Cell. Mol. Med. 2019 PMC6714494 10.1111/jcmm.14477 6 3 0 147 Humans|Male|*RNA, Circular|FOXP4 protein, human|*Forkhead Transcription Factors|MicroRNAs|Cell Proliferation|*Disease Progression|*Prostate Cancer|Up-Regulation|*Prostate|Cell Line, Tumor|RNA, Small Interfering|*Neoplastic Processes|MIRN1182 microRNA, human 80 FOXP4 31209207 Cell Death Dis 2019 PMC6572815 10.1038/s41419-019-1699-6 6 11 0 147 Humans|Male|*RNA, Long Noncoding|*RNA, Anti-Sense|*Upregulation|Cell Proliferation|FOXP4 protein, human|*Forkhead Transcription Factors|MicroRNAs|*Prostate Cancer|Gene Expression Regulation, Neoplastic|Apoptosis|RNA Interference|Oncogenesis|Cell Line, Tumor|Cell Movement|Oncogenes|*Transcriptional Activation|PAX5 protein, human|PAX5 Transcription Factor 80 FOXP4 31114338 Cancer Manag Res 2019 PMC6489618 10.2147/CMAR.S197979 3 5 0 147 80 FOXP4 31040716 Cancer Manag Res 2019 PMC6459146 10.2147/CMAR.S191641 1 4 0 147 Humans|*Up-Regulation|FOXP4 protein, human|*Forkhead Box Transcription Factors|Neoplasm Invasiveness|*Transcriptional Activation|Cell Movement|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Cell Proliferation|MicroRNAs|Cell Line, Tumor 80 FOXQ1 31853229 Int. J. Biol. Sci. 2019 PMC6909970 10.7150/ijbs.38000 0 0 0 388 Humans|*Carcinoma, Hepatocellular|*Epithelial-Mesenchymal Transition|*Liver Neoplasms|Neoplasm Recurrence, Local|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Prognosis|Hep G2 Cells|Cell Movement|Down-Regulation|Cell Line, Tumor|Forkhead Transcription Factors|Cancer Stem Cells|Carcinogenesis|FOXQ1 protein, human 139 FOXQ1 31713908 J. Clin. Lab. Anal. 2019 PMC6977110 10.1002/jcla.23031 1 0 0 388 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Prognosis|Gene Expression Regulation, Neoplastic|*Biomarkers|Forkhead Transcription Factors|Epithelial-Mesenchymal Transition|RNA, Messenger|FOXQ1 protein, human 139 FOXQ1 31517731 Anticancer Drugs 2019 10.1097/CAD.0000000000000801 0 4 0 388 Humans|Female|*Cell Migration|FOXQ1 protein, human|*Forkhead Transcription Factors|MicroRNAs|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Upregulation|Oncogene|MIRN342 microRNA, human 139 FOXQ1 31433456 Endocrinology 2019 PMC6804489 10.1210/en.2019-00177 0 6 0 388 Male|Humans|*Prostate|Estrogen Receptor beta|Estrogen Receptor alpha|Oestradiol|GPER1 protein, human|*Receptors, Estrogen|*Signal Transduction|Estrogens|Prostatic Neoplasms|MAP Kinase Signaling System|Phosphorylation|Cell Line, Tumor|CAV1 protein, human|Caveolin 1|Cell Nucleus|*Stem Cell|FOXQ1 protein, human|Forkhead Transcription Factors 139 FOXQ1 31417280 Onco Targets Ther 2019 PMC6592024 10.2147/OTT.S207593 0 3 0 388 139 FOXQ1 31404997 Cancers (Basel) 2019 PMC6721540 10.3390/cancers11081142 0 1 0 388 Humans|*Epigenome|Chromatin Immunoprecipitation|Histone|Histone Code|*Genes, Neoplasm|Acetylation|Sequencing, Next-Generation|Epigenesis, Genetic|Protein Processing, Post-Translational|Lysine|*Gene Expression|*Rectal Neoplasms 139 FOXQ1 31345147 Curr Alzheimer Res 2019 10.2174/1567205016666190725130134 3 12 0 388 *RNA, Long Noncoding|*Cyclooxygenase 2|*Alzheimer Disease|*Apoptosis|CDK5 protein, human|*Cyclin-Dependent Kinase 5|MicroRNAs|*Neurite Outgrowth|Cell Proliferation|Cell Line, Tumor|Signal Transduction|Inflammation|Adenocarcinoma of Lung|Lung Neoplasms|Neurons 139 FOXQ1 31137244 Math Biosci Eng 2019 10.3934/mbe.2019145 2 0 0 388 Humans|*Transcriptome|*Colorectal Cancer|Gene Ontology|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Prognosis|Databases, Genetic|Computational Biology|Biomarkers, Tumor|Up-Regulation|Downregulation|*Colonic Neoplasms|Signal Transduction|Genes, Regulator|Genes, cdc|FOXQ1 protein, human 139 FOXQ1 31116002 Cancer Med 2019 PMC6639256 10.1002/cam4.2236 1 0 0 388 Humans|*RNA, Long Noncoding|*mRNA|Sequencing, RNA|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|*Rectal Neoplasms|Adenocarcinoma 139 FOXQ1 30930929 Front Genet 2019 PMC6423895 10.3389/fgene.2019.00152 2 0 0 388 Humans|Animals|*Regulatory Regions|*Primate|Evolution, Molecular|Genome, Human|Chromatin|Chimpanzee|Deoxyribonuclease I|Quantitative Trait Loci|*Brain|Transcription Factors|Genomics|FOXQ1 protein, human|Forkhead Transcription Factors|GPR133 protein, human 139 FRG2 31817099 Molecules 2019 PMC6943618 10.3390/molecules24244428 0 0 0 17 Protein Interaction Mapping|Proteins|Protein Binding|Drug Discovery|Drug Evaluation, Preclinical 47 FRG2 31718611 BMC Public Health 2019 PMC6852998 10.1186/s12889-019-7878-7 1 0 0 17 Adolescent|Female|Humans|*Human Papilloma Virus|*Papillomavirus Infections|Papillomavirus Vaccines|*Vaccination|Cervical Cancer|*Qualitative Research|Immunization Programs|*School|Patient Acceptance of Health Care|Health Knowledge, Attitudes, Practice|*Chinese|Students|Surveys and Questionnaires|Hongkong 47 FRG2 31547459 Molecules 2019 PMC6767275 10.3390/molecules24183332 0 1 0 17 Mice|Animals|CA9 protein, human|*Carbonic Anhydrase IX|*Liposomes|*Carcinoma, Hepatocellular|*Cantharidin|*Liver Neoplasms|*Antibodies|Antigens, Neoplasm|Antineoplastic Agents|Drug Delivery Systems|Cell-Penetrating Peptides|Cell Line, Tumor|Hep G2 Cells 47 FRG2 31509940 Int J Mol Sci 2019 PMC6770765 10.3390/ijms20184445 3 1 0 17 Humans|KEAP1 protein, human|*Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|Neurodegenerative Diseases|Protein Binding|*GA-Binding Protein Transcription Factor|Small Molecule Libraries|Drug Discovery|Oxidative Stress 47 FRG2 31409381 BMC Public Health 2019 PMC6692951 10.1186/s12889-019-7438-1 1 0 0 17 Humans|*Lifestyle|*Students|Vegetable|Health Behavior|Physical Activity|Universities|Health Promotion|Fruit|Internet 47 FRG2 31357712 Molecules 2019 PMC6696146 10.3390/molecules24152739 2 0 0 17 *Iridium|*Apoptosis|Drug Screening Assays, Antitumor|Coordination Complexes|Anticancer Agents|Cell Line, Tumor|Cell Proliferation|Cisplatin|Cell Survival|Molecular Structure|Structure-Activity Relationship|Dose-Response Relationship, Drug 47 FRG2 31137782 Molecules 2019 PMC6572696 10.3390/molecules24102016 2 0 0 17 Animals|Mice|*BALB C Mice|Macrophage Activation|RAW 264.7 Cells|Macrophages|Signal Transduction|Receptors, Notch|NOS2 protein, human|Nitric Oxide Synthase Type II|Polysaccharides|Nitric Oxide|Phenotype|Gene Expression 47 FRG2 30968170 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03092-7 5 0 0 17 Humans|*Palmitic Acid|*Signal Transduction|Neurodegenerative Diseases|Inflammation|Cardiovascular Diseases|Cancer|Metabolic Syndrome|Autophagy|*Cytoplasm|*Biochemical Phenomena 47 FRG2 30789120 J Dev Orig Health Dis 2019 10.1017/S2040174419000060 0 0 0 17 Pregnancy|Female|Humans|Infant, Newborn|Rats|Animals|Adult|*Lactation|Ovaries|Reproduction|*Maternal-Fetal Exchange|Prenatal Exposure Delayed Effects|GDF9 protein, human|GDF-9|CYP19A1 protein, human|CYP19|Caloric Restriction|*Fetal Diseases|*Infant, Newborn, Diseases|Malnutrition 47 FRG2 30658419 Int J Mol Sci 2019 PMC6358942 10.3390/ijms20020381 9 0 0 17 *Blood-Brain Barrier|*Alzheimer Disease|Nanoparticles|*Biological Transport|Drug Delivery Systems|Drug Carriers|Liposomes|Polymers 47 FRG2 30650627 Int J Mol Sci 2019 PMC6359354 10.3390/ijms20020341 2 0 0 17 *Coordination Complexes|Antineoplastic Agents|*Biological Products|Metals|Neoplasms 47 FRG2 30650517 Cancers (Basel) 2019 PMC6360022 10.3390/cancers11010092 5 17 0 17 Humans|Female|KDM5A protein, human|*Retinoblastoma-Binding Protein 2|*MCF-7 Cells|Jumonji Domain-Containing Histone Demethylases|Histone|*Cell Cycle Arrest|Nuclear Proteins|Repressor Proteins 47 FRMD4A 31649738 Front Genet 2019 PMC6795747 10.3389/fgene.2019.00976 0 0 0 33 Humans|*Alzheimer Disease|Neurodegenerative Diseases|Neuroimaging|Functional Magnetic Resonance Imaging|Brain|Cognitive Dysfunction|Multimodal Imaging|Machine Learning|Positron-Emission Tomography|Image Interpretation, Computer-Assisted|Disease Progression|ROC Curve|Databases, Factual|CNTNAP2 protein, human|Membrane Proteins|Nerve Tissue Proteins 26 FRMD4A 31616461 Front Genet 2019 PMC6764289 10.3389/fgene.2019.00770 2 3 0 33 26 FRMD4A 30640082 Environ. Res. 2019 10.1016/j.envres.2019.01.001 2 1 0 33 Humans|Male|Pregnancy|Female|Adult|*Polychlorinated Biphenyls|*Dibenzofurans, Polychlorinated|*DNA Methylation|Dioxins|Environmental Pollutants|Benzofurans|Environmental Exposure|Cohort Studies|Prenatal Exposure Delayed Effects|*Parturition 26 Frzb 31860666 PLoS Genet. 2019 PMC6952110 10.1371/journal.pgen.1008533 0 0 0 374 Myxococcus xanthus|Chemotaxis|Signal Transduction|Bacterial Proteins|Phenotype 205 Frzb 31837466 Cell. Signal. 2019 10.1016/j.cellsig.2019.109471 0 0 0 374 Humans|*Chondrocytes|GREM1 protein, human|Intercellular Signaling Peptides and Proteins|Chondrogenesis|Osteoarthritis|Cartilage, Articular|IL1B protein, human|Interleukin 1 beta|Cell Differentiation|Wnt Signaling Pathway|Intracellular Signaling Peptides and Proteins|Matrix Metalloproteinases 205 Frzb 31810754 Blood Rev. 2019 10.1016/j.blre.2019.100646 0 0 0 374 Humans|*Multiple Myeloma|RANK Ligand|Receptor Activator of Nuclear Factor-kappa B|Osteolysis|Osteoclasts|Chemokine CCL3|Chemokine CCL4|Macrophage Inflammatory Proteins|Bone Remodeling|Membrane Glycoproteins|Cytokines|Carrier Proteins 205 Frzb 31302686 Rheumatology (Oxford) 2019 10.1093/rheumatology/kez269 0 3 0 374 Humans|*Wnt Signaling Pathway|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Alleles|*Catenins|Asian Continental Ancestry Group|beta Catenin|Sjogren's Syndrome|Case-Control Studies 205 Frzb 31204699 J. Genet. 2019 1 0 0 374 Animals|*Chickens|*INDEL Mutation|*Phenotype|Quantitative Trait Loci|Gene Annotations|Quantitative Trait, Heritable|Chromosome Mapping|Genomics|Genotype|*Feathers|High-Throughput Nucleotide Sequencing|Genetic Variation|Polymorphism, Single Nucleotide 205 Frzb 31027226 Nutrients 2019 PMC6520820 10.3390/nu11040935 3 0 0 374 *Selenium|*Selenoprotein|*Colorectal Cancer|Selenoprotein P|Single Nucleotide Polymorphisms|*Colonic Neoplasms|*Genotypes|Genetic Predisposition to Disease|Glutathione Peroxidase|Case-Control Studies|Risk Factors 205 Frzb 30947534 Cartilage 2019 10.1177/1947603519841676 1 2 0 374 Humans|WD repeat containing planar cell polarity effector|GREM1 protein, human|Intercellular Signaling Peptides and Proteins|Intracellular Signaling Peptides and Proteins|Knee Osteoarthritis|Chondrocytes|Fluid, Synovial|Glycoproteins|*Inflammation|Wnt Signaling Pathway|Biomarkers 205 FUBP1 31870915 J. Am. Acad. Dermatol. 2019 10.1016/j.jaad.2019.12.026 0 0 0 327 *Carcinoma, Basal Cell|Anilides|Skin Neoplasms|Hedgehog Proteins|Pyridines|Antineoplastic Agents|Signal Transduction 171 FUBP1 31587040 Carcinogenesis 2019 10.1093/carcin/bgz171 0 11 0 327 *Carcinoma, Hepatocellular|*Liver Cancer|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Hep G2 Cells|FUBP1 protein, human|*DNA-Binding Proteins|*RNA-Binding Proteins|*Neoplastic Processes|Transforming Growth Factor beta|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Wnt Signaling Pathway|Up-Regulation 171 FUBP1 31553912 Cell Rep 2019 PMC7297508 10.1016/j.celrep.2019.08.060 1 0 0 327 *Alternative Splicing|*Cancer|*Tumor Suppressor Genes|*Oncogene|DNA-Binding Proteins|RNA-Binding Proteins|DNA Helicases|Biomarkers, Tumor 171 FUBP1 31535751 Cell Biol. Int. 2019 10.1002/cbin.11242 0 3 0 327 Animals|*Clustered Regularly Interspaced Short Palindromic Repeats|Period Circadian Proteins|Circadian Rhythm|*Downregulation|Messenger RNA|Gene Expression Regulation|Nuclear Proteins|Mammals 171 FUBP1 31511046 J. Exp. Clin. Cancer Res. 2019 PMC6737630 10.1186/s13046-019-1414-6 1 2 0 327 Humans|Child|*Glycolysis|Neoplasm Recurrence, Local|*Neuroblastoma|FUBP1 protein, human|N-Myc Proto-Oncogene Protein|*RNA-Binding Proteins|Proto-Oncogene Proteins c-myc|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Down-Regulation|Disease Progression 171 FUBP1 31467227 Cancer Genomics Proteomics 2019 PMC6727075 10.21873/cgp.20138 0 0 0 327 Proto-Oncogene Proteins|Leukemia, Myeloid, Acute|Proto-Oncogene Proteins c-bcl-2|Myeloid Cell Leukemia Sequence 1 Protein|DNA-Binding Proteins|Vitamin C|Vitamins 171 FUBP1 31423172 Oncol Lett 2019 PMC6607041 10.3892/ol.2019.10444 3 0 0 327 *Computational Biology|Phosphatidylinositol 3-Kinases|Protein Interaction Maps|Gene Ontology|Gene Regulatory Networks|*Pancreatic Cancer|Gene Expression Profiling|Gene Expression Profiles|Gene Expression Regulation, Neoplastic|Protein Interaction Mapping|TCF7L1 protein, human|*Transcription Factor 7-Like 1 Protein|Software|Transcription Factor|Prognosis|Biomarkers, Tumor|Clustering|High-Throughput Nucleotide Sequencing 171 FUBP1 31415916 Pharmacol. Res. 2019 10.1016/j.phrs.2019.104398 1 0 0 327 Humans|folfirinox|*Irinotecan|Antineoplastic Combined Chemotherapy Protocols|Pancreatic Cancers|sacituzumab govitecan|Camptothecine|Immunoconjugates|Antineoplastic Agents|Antibodies, Monoclonal, Humanized|Topoisomerase I Inhibitors|7-ethyl-7-hydroxy-10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,12H)-dione|Indolizines|Fluorouracil|Neutropenia|Leucovorin|Oxaliplatin|Benzodioxoles|Japan 171 FUBP1 31405148 Cancers (Basel) 2019 PMC6721570 10.3390/cancers11081148 2 0 0 327 Humans|*Glioblastoma|Brain Neoplasms|Tumor Burden|Mutation|Retrospective Studies|IDH1 protein, human|Isocitrate Dehydrogenase 171 FUBP1 31229693 J Proteomics 2019 10.1016/j.jprot.2019.103420 0 0 0 327 171 FUBP1 31217899 Oncotarget 2019 PMC6557204 10.18632/oncotarget.26950 0 0 0 327 Humans|*Oligodendroglioma|*Heterografts|Neoplasm Recurrence, Local|Isocitrate Dehydrogenase|Brain Neoplasms|DNA Helicases|Mutation|Repressor Proteins|DNA-Binding Proteins|Chromosome Aberrations|Disease-Free Survival|*Transplantation, Heterologous|High-Throughput Nucleotide Sequencing 171 FUBP1 30871777 Biochem. 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Commun. 2019 10.1016/j.bbrc.2019.03.005 1 4 0 327 *Proto-Oncogene Proteins c-akt|*Up-Regulation|*Lactate|MTOR protein, human|*TOR Serine-Threonine Kinases|Hexokinase|Glycolysis|Signal Transduction|Cell Proliferation|Cell Line, Tumor|Glucose|Oxidative Phosphorylation|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Cell Survival 171 FUBP1 30653565 PLoS ONE 2019 PMC6336336 10.1371/journal.pone.0210515 2 4 0 327 TAL1 protein, human|*T-Cell Acute Lymphocytic Leukemia Protein 1|FUBP1 protein, human|GATA1 protein, human|GATA1 Transcription Factor|Transcription Factors|*Cell Differentiation|*RNA-Binding Proteins|Erythropoiesis|Gene Expression Regulation|Basic Helix-Loop-Helix Transcription Factors|Erythroid Cells|*Upregulation|Erythroid Progenitor Cells|Helix-Loop-Helix Motifs|*Transcriptional Activation|LIM Domain Proteins|Proto-Oncogene Proteins 171 FUBP1 30635626 Leukemia 2019 10.1038/s41375-018-0358-8 1 2 0 327 Mice|Humans|Animals|FUBP1 protein, human|*DNA-Binding Proteins|Fusion Proteins, bcr-abl|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Leukemia, Myeloid, Acute|*RNA-Binding Proteins|Hematopoietic Stem Cells|Cell Proliferation|Apoptosis|Cell Line, Tumor|Neoplastic Stem Cells|Cell Cycle 171 FUT2 31867815 Pathol. Int. 2019 10.1111/pin.12882 0 0 0 3485 *CA-19-9 Antigen|*Stomach Neoplasms|*Autopsy|Carcinoembryonic Antigen|MUC1 protein, human|Mucin-1|Biomarkers, Tumor|Lymphatic Metastasis|Lymph Node|galactoside 2-alpha-L-fucosyltransferase|Fucosyltransferases|Carbohydrates 385 FUT2 31850076 Front Genet 2019 PMC6901973 10.3389/fgene.2019.01230 1 0 0 3485 Child|Humans|Genome-Wide Association Study|*Otitis Media|Microbiome|*Microbial Interactions|Bacteria|*Epistasis, Genetic 385 FUT2 31784953 Hum. Cell 2019 10.1007/s13577-019-00304-x 0 8 0 3485 Male|Mice|Animals|*Testis|*Spermatogenesis|seminolipid|*Glycolipids|galactoside 2-alpha-L-fucosyltransferase|Fucosyltransferases|Spermatids|*Glycosylation|Spermatozoa|Spermatocytes 385 FXYD5 31867269 Front Oncol 2019 PMC6908519 10.3389/fonc.2019.01306 1 0 0 129 81 FXYD5 31746425 Int. J. Oncol. 2019 10.3892/ijo.2019.4911 1 7 0 129 Mice|Animals|Female|Humans|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|SMAD3 protein, human|Smad3 Protein|Smad Proteins|SMAD4 protein, human|Smad4 Protein|Transforming Growth Factor beta|Epithelial-Mesenchymal Transition|Signal Transduction|Cell Line, Tumor|*Neoplastic Processes|Cell Movement|Transcription, Genetic|FXYD5 protein, human|Membrane Glycoproteins|Neoplasm Proteins|FXYD5 protein, mouse 81 FXYD5 31434988 Br. J. Cancer 2019 PMC6889357 10.1038/s41416-019-0553-z 1 0 0 129 Humans|Female|*Platinum|*Up-Regulation|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Prognosis|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Transcriptional Activation|Gene Expression Profiling|FXYD5 protein, human|Membrane Glycoproteins|Neoplasm Proteins 81 FXYD5 30772174 Mol. Cell 2019 10.1016/j.molcel.2019.01.042 6 0 0 129 *Cellular Reprogramming|*RNA-Seq|Induced Pluripotent Stem Cells|POU5F1 protein, human|Octamer Transcription Factor-3|SOX2 protein, human|SOXB1 Transcription Factors|Cell Differentiation|Embryonic Stem Cells|Cell Lineage|Transcription Factors|*Diploidy|Gene Expression Regulation, Developmental|*B Cells|*Whole Exome Sequencing|Cells, Cultured 81 FXYD5 30726901 Glycobiology 2019 PMC6430981 10.1093/glycob/cwz004 1 1 0 129 Mice|Animals|*Antibodies, Monoclonal|*Glycoproteins|Epitopes|Mucin-1|Glycopeptides|Glycosylation|*Antineoplastic Agents, Immunological|Cell Line, Tumor|Amino Acid Sequence 81 GABRD 31611775 Front Cell Neurosci 2019 PMC6776584 10.3389/fncel.2019.00433 0 0 0 33 Adolescent|Humans|*Myoclonic Epilepsy, Juvenile|White Matter|Imaging, Magnetic Resonance|Corpus Callosum|Epilepsy, Generalized|Diffusion Tensor Imaging|Brain|Thalamus|Grand Mal Convulsions|Anisotropy|Functions, Executive|*Brain Diseases|Neurons 105 GABRD 31581124 Eur. J. Endocrinol. 2019 10.1530/EJE-19-0194 3 0 0 33 *ACTH-Secreting Pituitary Adenoma|*Transcriptome|Cushing Disease|Adenoma|Pituitary Neoplasms|Ubiquitin Thiolesterase|*Mutations|Endosomal Sorting Complexes Required for Transport|Endopeptidases|Corticotroph|Adrenocorticotropic Hormone|Pituitary Gland|*Microarray Analysis 105 GABRD 31545245 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109215 0 0 0 33 Adult|Humans|*Receptors, GABA-A|*Prognosis|*Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Mutation|Biomarkers, Tumor 105 GABRD 31454673 Behav. Brain Res. 2019 10.1016/j.bbr.2019.112178 0 7 0 33 Animals|Mice|*Receptors, GABA-A|*Catfish|*Essential Oils|*Lauraceae|Anesthetics|Flumazenil|Plant Oils|GABAergic Effects|Sedative Effects|Anesthesia|Diazepam|*Brain|Gabra2 protein, mouse 105 GABRD 31279243 J Psychiatr Res 2019 PMC6941851 10.1016/j.jpsychires.2019.05.030 3 0 0 33 Humans|*Bipolar Disorder|*B-DNA|*Temporal Cortices|Depressive Disorder, Major|Grey Matter|Dorsolateral Prefrontal Cortex|Brain|Magnetic Resonance Imaging|Cerebral Cortex|DNA Methylation 105 GABRD 31277598 BMC Cancer 2019 PMC6612102 10.1186/s12885-019-5838-3 6 0 0 33 *Carcinoma, Hepatocellular|*Liver Cancer|Early Detection of Cancer|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Gene Regulatory Networks|Transcriptome|Databases, Genetic|Cluster Analysis|Liver 105 GABRD 31147611 Sci Rep 2019 PMC6542821 10.1038/s41598-019-44286-0 0 1 0 33 Female|Male|*Alcohol Drinking|*Ethanol|Receptors, GABA-A|Neurotransmission|Synapses|gamma-Aminobutyric Acid 105 GABRD 31056551 Genet. Med. 2019 10.1038/s41436-019-0531-0 2 0 0 33 Humans|*Epilepsy|*Disorder, Neurodevelopmental|Genetic Testing|Genetic Association Studies|Genetic Predisposition to Disease|Genetic Variation 105 GABRD 31020692 J. Cell. Biochem. 2019 10.1002/jcb.28773 1 0 0 33 Humans|*Computational Biology|*Glioma|Gene Expression Profiling|Prognosis|Protein Interaction Maps|Biomarkers, Tumor|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Transcriptome|Disease Progression 105 GABRD 30851244 Brain Res. 2019 10.1016/j.brainres.2019.03.004 3 0 0 33 Receptors, GABA-A|Epilepsy|Mutation|Mutation, Missense|gamma-Aminobutyric Acid 105 GABRD 30615651 PLoS ONE 2019 PMC6322723 10.1371/journal.pone.0210094 3 2 0 33 Animals|Mice|*Receptors, GABA A|*Prealbumin|Inhibitory Postsynaptic Potentials|Neural Inhibition|Neurons|Synaptic Transmission|Synapses|Cerebellum|Thalamus|gamma-Aminobutyric Acid|Interneurons|Hippocampus|Protein Subunits 105 GABRG1 31790348 J Stud Alcohol Drugs 2019 PMC6900988 0 0 0 26 Humans|*Chromosomes, Human, Pair 4|*Alcohol Drinking|Alcohol Use Disorder|*Antisocial Personality Disorder|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Alleles|Genotype|Receptors, GABA-A 48 GABRG1 31786770 J Youth Adolesc 2019 PMC7260088 10.1007/s10964-019-01171-3 0 0 0 26 Adolescent|Male|Humans|Child|Young Adult|Adult|Female|Longitudinal Studies|*Peer Group|Adolescent Behavior|Gene-Environment Interaction|Michigan 48 GABRG1 31290690 J. Comput. Biol. 2019 10.1089/cmb.2019.0179 0 0 0 26 Humans|*Prognosis|Gene Ontology|Gene Expression Profiling|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|DNA Methylation|Gene Expression Profiles|Databases, Genetic|Computational Biology|Biomarkers, Tumor|Protein Interaction Maps|Kaplan-Meier Estimate 48 GABRG1 31235723 Sci Rep 2019 PMC6591351 10.1038/s41598-019-45520-5 1 0 0 26 Animals|*Chickens|Quantitative Trait Loci|Genome-Wide Association Study|*Body Weight|SNPs|Quantitative Trait, Heritable|Phenotype|Genomics|Module, Gene 48 GABRG1 31026301 PLoS ONE 2019 PMC6485638 10.1371/journal.pone.0215745 0 0 0 26 Humans|Child|Female|Pregnancy|*DNA Methylation|CpG Islands|*Placenta|Epigenesis, Genetic|Epigenetic|Maternal Exposure|Birth Weight|Genome-Wide Association Study|Smoking|Night Shift Work|Tobacco Smoking|Linear Models|Rhode Island|CLEC16A protein, human|Monosaccharide Transport Proteins|Lectins, C-Type|FAM172A protein, human|Proteins 48 GABRG1 31011876 Arch. Dermatol. Res. 2019 PMC6594982 10.1007/s00403-019-01915-y 0 0 0 26 *Alleles|ADH1B protein, human|Case-Control Studies|*Prevalence|Hungary|Alcohol Dehydrogenase|*Alcohol Consumption|Aldehyde Dehydrogenase, Mitochondrial|SNPs|Alcoholism|Genotype|Aldehyde Dehydrogenase|*Psoriasis 48 GABRG1 30851244 Brain Res. 2019 10.1016/j.brainres.2019.03.004 3 0 0 26 Receptors, GABA-A|Epilepsy|Mutation|Mutation, Missense|gamma-Aminobutyric Acid 48 GABRG1 30619995 Hepatol Commun 2019 PMC6312655 10.1002/hep4.1286 1 0 0 26 Animals|Humans|Mice|Quality of Life|*Mice, Inbred C57BL|Encephalopathy, Hepatic|*Liver Cirrhosis|fMRI|Brain|*Brain Diseases|Neuropsychological Tests 48 GABRP 31624295 Sci Rep 2019 PMC6797726 10.1038/s41598-019-51453-w 1 1 0 19 Humans|Mice|Animals|*Triple-Negative Breast Cancer|Mice, Nude|*Biologics|Xenograft Model Antitumor Assays|Cell Proliferation|Cell Line, Tumor|Antineoplastic Agents|Mertansine|Cell Cycle|Immunoconjugates|Apoptosis|GABRP protein, human|Receptors, GABA-A 40 GABRP 30826748 Gut 2019 10.1136/gutjnl-2018-317479 3 4 0 19 Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Macrophage|Signal Transduction|Xenograft Model Antitumor Assays|Cell Proliferation|Cell Line, Tumor|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Tumorigenesis|Chemokines 40 GAGE1 31607938 Front Physiol 2019 PMC6761273 10.3389/fphys.2019.01155 2 0 0 20 Humans|Male|Infant|Child|*Adult Germline Stem Cells|Spermatogonia|Spermatogenesis|Seminiferous Tubules|*Boys|Testis|Sertoli Cells|*Reproduction|Cryopreservation|Stem Cells|Cells, Cultured|Preservations, Fertility|Cell Differentiation|Cell Proliferation 48 GALM 31838905 Hypertension 2019 10.1161/HYPERTENSIONAHA.119.13197 3 0 0 50 Humans|*Renin-Angiotensin System|*Cohort Studies|Retrospective Studies|Angiotensin II Receptor Blockers|Angiotensin-Converting Enzyme Inhibitors|Hypertension|Risk Factors|Proportional Hazards Model|Propensity Score|*Sepsis 173 GALM 31749923 Gastroenterol Hepatol Bed Bench 2019 PMC6820838 2 0 0 50 *Celiac Disease|*Antioxidants|Glutens|Diet, Gluten-Free|Triticum|*Carbohydrate Metabolism 173 GALM 31292255 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6660739 10.1073/pnas.1902041116 0 0 0 50 Craniosynostosis|*Mutations|Whole Exome Sequencing|Exome|Skull 173 GALM 31280477 Anal Bioanal Chem 2019 10.1007/s00216-019-01986-w 0 0 0 50 graphitic carbon nitride|soybean lectin|*Graphite|*Biosensor|*Nitrogen Compounds|*Plant Lectins|*Soybean Proteins|Gold|Electrochemical Techniques|Metal Nanoparticles|Luminescent Measurements|Limit of Detection|cyanogen|Nitriles|Nanostructures|*Carboxylic Acids 173 GALM 31234461 Int J Mol Sci 2019 PMC6627059 10.3390/ijms20123045 3 0 0 50 Humans|Rats|Animals|trimethyloxamine|*Myocytes, Cardiac|*Membrane Potential, Mitochondrial|*Reactive Oxygen Species|*Methylamines|L-Carnitine|Choline|Atherosclerosis|Cells, Cultured|Disease Models, Animal 173 GALM 31226710 FEMS Microbiol. Lett. 2019 10.1093/femsle/fnz137 0 1 0 50 *Clustered Regularly Interspaced Short Palindromic Repeats|Pectobacterium atrosepticum|CRISPR-Cas Systems|Plasmids|Pectobacterium|Genome, Bacterial|Phage|Bacteria|Operon|Genomics 173 GALM 31133029 BMC Microbiol. 2019 PMC6537148 10.1186/s12866-019-1487-6 1 0 0 50 Humans|Animals|*Genomic Islands|*Vibrio parahaemolyticus|Gene Transfer, Horizontal|Phylogeny|Evolution, Molecular|Virulence|Bacterial Proteins|Bacteria|*Carbohydrate 173 GALM 30910422 Mol. Genet. Metab. 2019 10.1016/j.ymgme.2019.01.018 0 0 0 50 *Galactosemias|*Prevalence|UTP-Hexose-1-Phosphate Uridylyltransferase|UDPglucose 4-Epimerase|Galactose|*Mutations|*Data Management 173 GALM 30675661 Surg Endosc 2019 10.1007/s00464-019-06672-7 2 0 0 50 Humans|*Robotic Surgical Procedures|*Propensity Score|*Hospital Records|*Laparoscopic Surgery|*Colon Cancer|Retrospective Studies|Length of Stay|*Databases, Factual|Postoperative Complications|Colon 173 GCM1 31392209 Biomed Res Int 2019 PMC6662495 10.1155/2019/2098749 0 0 0 325 Pregnancy|Female|Humans|*Keratin-7|*Multipotent Stem Cells|*Placenta|Cell Differentiation|*Intermediate Filament Proteins|Cells, Cultured|Immunophenotyping 162 GCM1 31278978 Reprod. Toxicol. 2019 10.1016/j.reprotox.2019.07.001 0 1 0 325 Pregnancy|Humans|Female|*Trophoblasts|bisphenol A|*Benzhydryl Compounds|*Phenols|syncytin|Gene Products, env|Pregnancy Proteins|*Endogenous Retroviruses|Placenta|Cell Fusion|Endocrine Disruptors|Gene Expression|Cell Line 162 GCM1 31133638 Sci Rep 2019 PMC6536531 10.1038/s41598-019-44161-y 0 1 0 325 Mice|Animals|*Kidney|*Regeneration|*Ischemia-Reperfusion Injury|*Fibrosis|Acute Kidney Injury|*Cell Proliferation|Kidney Tubules|Kidney Tubules, Proximal|Mice, Knockout|Epithelial Cells|*Cells, B-1|Ischemia|*Cells, Glial 162 GCM1 30974885 Genes (Basel) 2019 PMC6523153 10.3390/genes10040293 0 0 0 325 162 GCM1 30896984 DNA Cell Biol. 2019 10.1089/dna.2018.4458 0 1 0 325 Pregnancy|Female|Humans|Trophoblast|Embryonic Stem Cells|Octamer Transcription Factor-3|CDX2 Transcription Factor|Cell Lineage|Transcription Factors|Cell Differentiation|Homeodomain Proteins|*Wnt Pathway|Blastocyst|Gene Expression Regulation, Developmental|Promoter Regions, Genetic|WNT3A protein, human|Wnt3A Protein 162 GCM1 30873821 Cell. Physiol. Biochem. 2019 10.33594/000000033 1 0 0 325 Mice|Pregnancy|Female|Animals|*Pregnancy Outcome|*Iron|*TRPC6 Cation Channel|Placenta|*Homeostasis|Pre-Eclampsia|Zinc|TRPC Cation Channels|Biological Transport|Trpc6 protein, mouse 162 GCM1 30765769 Sci Rep 2019 PMC6376060 10.1038/s41598-018-38336-2 2 6 0 325 Humans|Infant, Newborn|Female|Pregnancy|*Rosiglitazone|*Inflammation Mediators|*Placenta|Trophoblast|Placentation|Pre-Eclampsia|Cell Differentiation|PPAR gamma|Cell Line|Transcription Factors|Inflammation 162 GCNT2 31621365 Immunohematology 2019 0 0 0 20 37 GCNT2 31213534 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6628663 10.1073/pnas.1900268116 1 0 0 20 Galectins|Glycosylation|N-acetylglucosaminyltransferase IGnT|N-Acetylglucosaminyltransferases|Glycans|Signal Transduction|*Disease Progression|Protein Binding|Cancer|B-Lymphocytes|Cell Membrane 37 GCNT2 30885246 Stem Cell Res Ther 2019 PMC6423778 10.1186/s13287-019-1209-x 8 3 0 20 Humans|Aged|*Induced Pluripotent Stem Cells|*Rejuvenation|Mesenchymal Stem Cells|Cell Differentiation|Cell Proliferation 37 GIGYF2 31709175 Front Oncol 2019 PMC6823876 10.3389/fonc.2019.01063 0 0 0 191 64 GIGYF2 31098421 Investig Clin Urol 2019 PMC6495037 10.4111/icu.2019.60.3.148 0 0 0 191 Humans|Clear Cell Renal Cell Carcinoma|Kidney Neoplasms|Kidney Diseases, Cystic|Kidney|Prognoses|Diagnosis, Differential 64 GIGYF2 30977120 Int. J. Cancer 2019 PMC7111256 10.1002/ijc.32334 2 4 0 191 Humans|*PR-SET Domains|Neoplasm Recurrence, Local|*Neuroendocrine Tumors|SETD1B protein, human|Histone-Lysine N-Methyltransferase|Sequencing, Whole Exome|Liver Neoplasms|Mutations|Prognosis|Transcription Factors|Tumor Suppressor Protein p53|*Gastrointestinal Neoplasms|Cell Proliferation|WDR5 protein, human|UBR4 protein, human|Calmodulin-Binding Proteins|Cytoskeletal Proteins|ATAD5 protein, human 64 GIGYF2 30929901 Cell 2019 PMC6494450 10.1016/j.cell.2019.01.048 15 0 0 191 Humans|*Schizophrenia|*Phenotypes|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Brain|Gene Expression Regulation|Brain Mapping|Genome 64 GIGYF2 30917308 Cell Rep 2019 10.1016/j.celrep.2019.03.006 2 1 0 191 ZFP36 protein, human|*Tristetraprolin|Rich Element, AU|RNA Stability|mRNA|*Gene Expression Regulation|*Signal Transduction|Cytokines|Inflammation 64 GIGYF2 30616710 Animal 2019 10.1017/S1751731118003610 4 0 0 191 Sheep|Animals|*Genome-Wide Association Study|*Birth Weight|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Genotype|Breeding|Phenotype|Oligonucleotide Array Sequence Analysis 64 GIGYF2 30610028 Blood 2019 10.1182/blood-2018-05-852822 20 0 0 191 Humans|*Clonal Evolution|*Leukemia, Myeloid, Acute|Mutation|*Genomics|Translocation, Genetic|High-Throughput Nucleotide Sequencing|Relapse 64 GIGYF2 30598256 Neurobiol. Aging 2019 10.1016/j.neurobiolaging.2018.11.012 1 0 0 191 Humans|Parkinson Disease, Familial, Type 1|*Parkinson Disease|*Genes, Dominant|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|alpha-Synuclein|*Chinese|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Protein-Serine-Threonine Kinases|Genotype|*Cohort Studies|Vesicular Transport Proteins|Phenotype|CHCHD2 protein, human|Transcription Factors|Mitochondrial Proteins 64 GIMAP4 31496804 Cancer Manag Res 2019 PMC6689548 10.2147/CMAR.S201177 3 0 0 68 *Squamous Cell Carcinoma of Head and Neck|*Gene Regulatory Networks|Head and Neck Neoplasms|Gene Expression Profiling|Transcriptome|Tumorigenesis 29 GIMAP4 30598658 Clin Proteomics 2019 PMC6302491 10.1186/s12014-018-9215-z 5 0 0 68 Humans|Female|Liquid Chromatography|*Carcinoma, Ovarian Epithelial|*Peptides|Spectrometry, Mass, Electrospray Ionization|Tandem Mass Spectrometry|Proteomics|Proteins|*Ovarian Cancer|*Plasma|Algorithms 29 GLCCI1 31516081 J Asthma 2019 10.1080/02770903.2019.1666867 1 1 0 103 47 GLCCI1 31391381 Biol. 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Bull. 2019 10.1248/bpb.b19-00476 0 1 0 103 Humans|*Glucocorticoids|Leukocytes, Mononuclear|*Asthma|Receptors, Glucocorticoid|Adrenal Cortex Hormones|*Gene Expression|Administration, Inhalation|HDAC2 protein, human|Histone Deacetylase 2|Genotype|Polymorphism, Single Nucleotide 47 GLCCI1 31178722 Front Pharmacol 2019 PMC6537658 10.3389/fphar.2019.00520 3 1 0 103 Humans|*Pharmacogenetics|*Asthma|*Pharmacogenomic Testing|Anti-Asthmatic Agents|Corticosteroids|Leukotriene Antagonists|Adrenergic beta-Agonists|Leukotrienes|3'-(1-butylphosphoryl)adenosine|*Complement Factor B|Inflammation 47 GLCCI1 31022961 Int J Mol Sci 2019 PMC6514776 10.3390/ijms20082024 1 4 0 103 47 GLCCI1 30937140 World Allergy Organ J 2019 PMC6439416 10.1016/j.waojou.2019.100017 0 0 0 103 *Corticosteroids|*Asthma|Glucocorticoid|Receptors, Glucocorticoid|Administration, Inhalation|Forced Expiratory Volume|Genotype|Polymorphism, Single Nucleotide|*Drug Hypersensitivity 47 GLCCI1 30860871 FASEB J. 2019 10.1096/fj.201800344RR 0 12 0 103 Humans|*Glucocorticoids|Receptors, Glucocorticoid|Thymocyte|Apoptosis|*Cell Death|Cells, Cultured 47 GLCCI1 30647901 Clin Transl Allergy 2019 PMC6327448 10.1186/s13601-018-0239-2 3 0 0 103 Genome-Wide Association Study|*Corticosteroids|*Asthma|Administration, Inhalation|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pharmacogenetics 47 GLDN 31413919 Oncoimmunology 2019 PMC6682357 10.1080/2162402X.2019.1608132 1 0 0 88 Humans|*Melanoma|CTLA4 protein, human|CTLA-4 Antigen|Programmed Cell Death 1 Receptor|Immunotherapy|Antibodies, Monoclonal|Biomarkers, Tumor 30 GLDN 30971289 Vet. Res. 2019 PMC6458827 10.1186/s13567-019-0641-3 0 0 0 88 Animals|*Flavobacterium|*Hydrocortisone|Flavobacterium columnare|Flavobacteriaceae Infections|Biofilms|Fish Diseases|Bacterial Proteins 30 GLDN 30732576 J Neurodev Disord 2019 PMC6366120 10.1186/s11689-019-9263-3 1 0 0 88 *DNA Copy Number Variations|*Neurodevelopmental Disorders|Sequencing, Whole Genome|Gene Dosage|Phenotype|Mutation 30 GLDN 30654001 Gene 2019 10.1016/j.gene.2019.01.001 8 0 0 88 Humans|*Computational Biology|*Prognosis|*Colorectal Cancer|Gene Ontology|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Databases, Genetic|Gene Expression Profiling|Gene Regulatory Networks|Transcriptome|*Colonic Neoplasms 30 GLIPR2 30700571 Biosci. Rep. 2019 PMC6900432 10.1042/BSR20182345 2 0 0 52 *Amyloid|*Amyloidogenic Proteins|*Amyloidosis|Binding Sites|Zinc|*Chelating Agents 21 glis1 31806618 Biol Open 2019 PMC6918770 10.1242/bio.047225 1 0 0 33 Humans|*Cellular Reprogramming|Induced Pluripotent Stem Cells|Octamer Transcription Factor-3|Nanog Homeobox Protein|Transcription Factors|Homeodomain Proteins|SOXB1 Transcription Factors|Cell Differentiation|Proto-Oncogene Proteins c-myc|Fibroblasts|DOT1L protein, human|Histone-Lysine N-Methyltransferase|NANOG protein, human 45 glis1 31504761 Mol. Biol. Evol. 2019 PMC6984359 10.1093/molbev/msz205 0 0 0 33 Animals|Phylogeny|Transcription Factors|Kruppel-Like Transcription Factors|Vertebrate|Genome|Gene Cluster|Induced Pluripotent Stem Cells|*Biological Phenomena|*Biological Evolution 45 glis1 31474360 Trends Cancer 2019 PMC6777873 10.1016/j.trecan.2019.07.005 0 1 0 33 Humans|Child|*Transcription Factors|*Zinc Finger|GLI1 protein, human|*Zinc Finger Protein GLI1|CBFA2T3 protein, human|Repressor Proteins|Kruppel-Like Transcription Factors|Tumor Suppressor Proteins|*Leukemia|*Cancers|Signal Transduction|Leukemia, Megakaryoblastic, Acute|Epithelial-Mesenchymal Transition|Cell Differentiation 45 glis1 31373774 Cancer Cytopathol 2019 10.1002/cncy.22163 0 0 0 33 *Thyroid Nodule|*Thyroid Neoplasm|Papillary Thyroid Carcinoma|Thyroidectomy|Thyroid Gland|Biopsy, Fine-Needle|Biomarkers, Tumor|Diagnosis, Differential 45 glis1 31273314 Mod. Pathol. 2019 10.1038/s41379-019-0313-x 0 0 0 33 *Thyroid Gland|In Situ Hybridization, Fluorescence|*Thyroid Neoplasms|Carcinoma, Papillary|*Gene Fusion|*Mutation|PAX8 Transcription Factor|Gene Rearrangement|Transcription Factors|DNA-Binding Proteins|Trans-Activators|Adenoma|Carcinomas|Adenoma, Oxyphilic|Immunohistochemistry 45 glis1 31216469 Cell Rep 2019 10.1016/j.celrep.2019.05.068 1 0 0 33 Mice|Animals|*Pluripotent Stem Cells|Induced Pluripotent Stem Cells|Cellular Reprogramming|POU5F1 protein, human|Octamer Transcription Factor-3|Embryonic Stem Cells|Nanog Homeobox Protein|Transcription Factors|Homeodomain Proteins|SOX2 protein, human|SOXB1 Transcription Factors|Fibroblasts|Cell Differentiation|Cells, Cultured|Chromatin|Chimera|Gene Expression Profiling|Nanog protein, mouse 45 glis1 31112420 Circ Genom Precis Med 2019 PMC6532425 10.1161/CIRCGEN.119.002497 1 0 0 33 Mice|Animals|*Mitral Valve Prolapse|*Genome-Wide Association Study|*Follow-Up Studies|Mitral Regurgitation|Mitral Valve|Heart Valve Disease|Genetic Susceptibility|Phenotype|Case-Control Studies|Extracellular Matrix|Zebrafish 45 glis1 30648929 Thyroid 2019 PMC6389773 10.1089/thy.2018.0791 4 0 0 33 Humans|*Thyroid Neoplasm|*Gland, Thyroid|Papillary Thyroid Carcinoma|PAX8 Transcription Factor|Biopsy, Fine-Needle|Gene Rearrangement|*Genomics|Gene Expression Regulation, Neoplastic 45 GLRX 31869414 Blood Adv 2019 PMC6929385 10.1182/bloodadvances.2019000677 2 0 0 415 Humans|*Bone Marrow|*Antioxidants|Hydrogen Peroxide|*Myelodysplastic Syndromes|Leukemia, Myeloid, Acute|Bone Marrow Cells|Cells, Cultured|Disease Progression|Stem Cell|Flow Cytometry|*Redox|Oxidative Stress 191 GLRX 31851787 Mol Genet Genomic Med 2019 PMC6978401 10.1002/mgg3.1010 1 0 0 415 *Epistasis, Genetic|Genetic Predisposition to Disease|*Heart Defects, Congenital|Polymorphism, Single Nucleotide|Folate|Case-Control Studies|Risk Factors 191 GLRX 31813265 Antioxid. Redox Signal. 2019 PMC7047114 10.1089/ars.2019.7963 1 0 0 415 191 GLRX 31693398 Am. J. Physiol., Cell Physiol. 2019 PMC7052607 10.1152/ajpcell.00410.2019 2 0 0 415 GLRX protein, human|*Glutaredoxins|Glutathione|Redox|Cysteine|Oxidative Stress|Sulfhydryl Compounds|Antioxidants|Lung|Proteins|Protein Processing, Post-Translational 191 GLRX 31647879 FASEB J. 2019 PMC6894059 10.1096/fj.201900786R 0 1 0 415 Mice|Animals|*Neovascularization, Pathologic|GLRX protein, human|Glutaredoxin 1|*Redox|Hindlimb|Neovascularization, Physiologic|Ischemia|Endothelial Cells|Vascular Endothelial Growth Factor A|Cell Movement|Signal Transduction|*Morphogenesis|Disease Models, Animal|*Cardiovascular Physiological Phenomena|*Neoplasms|Glrx protein, mouse 191 GLRX 31563783 Environ. Pollut. 2019 10.1016/j.envpol.2019.113256 0 14 0 415 *Lycopersicon esculentum|GLRX protein, human|*Glutaredoxins|brassinolide|*Brassinosteroids|tetrachloroisophthalonitrile|Steroids, Heterocyclic|*Nitriles|Gene Expression Regulation, Plant|Redox|Plant Proteins|Hydrogen Peroxide|Glutathione|Reactive Oxygen Species|NADPH Oxidases|Gene Silencing|Signal Transduction 191 GLRX 31537820 Sci Rep 2019 PMC6753157 10.1038/s41598-019-49624-w 3 0 0 415 Mice|Animals|Humans|*Dependovirus|HEK293 Cells|Gene Therapy|Genetic Vectors|Gene Transfer Techniques|Genome Editing|iodixanol|Triiodobenzoic Acids 191 GLRX 31417181 Oncogene 2019 10.1038/s41388-019-0935-y 3 5 0 415 *RNA, Long Noncoding|Neoplasm Recurrence, Local|*Lung Adenocarcinoma|Lung Cancer|Adenocarcinoma|Cell Lines, A549|Gene Expression Regulation, Neoplastic|Transcriptome Analysis|Cell Proliferation|Upregulation|Cell Line, Tumor|*Hypoxia|Exons|*Oxidative Stress|*Phenotype 191 GLRX 31345023 J. Agric. Food Chem. 2019 10.1021/acs.jafc.9b03136 1 6 0 415 Mice|Animals|KEAP1 protein, human|*Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Lipogenesis|*Liver|*Signal Transduction|*Inflammation|Nonalcoholic Fatty Liver Disease|*GA-Binding Protein Transcription Factor|*Upregulation|Oxidative Stress|TYRP1 protein, human|Adaptor Proteins, Signal Transducing|*Membrane Glycoproteins|Diet, High-Fat|Mice, Inbred C57BL|Cytoskeletal Proteins 191 GLRX 31176019 Cell. Signal. 2019 10.1016/j.cellsig.2019.06.005 1 6 0 415 Humans|Mice|Animals|Histone|Phosphorylation|TXN protein, human|Thioredoxin|DNA Replication|DNA Breaks, Double-Stranded|DNA Damage|Nuclear Proteins|Carrier Proteins|Protein Kinase C|Signal Transduction|Protein Processing, Post-Translational|Cell Line, Tumor|Camptothecine|Jurkat Cells|DNA|GLRX3 protein, human|Glrx protein, mouse 191 GLRX 31085544 Drug Metab. Dispos. 2019 10.1124/dmd.118.086132 0 0 0 415 Humans|Animals|Rats|*Antibody-Drug Conjugates|GLRX protein, human|Glutaredoxin|TXN protein, human|Thioredoxin|Thioredoxin Reductase|Disulfides|Glutathione|Cysteine|pyrrolo(2,1-c)(1,4)benzodiazepine|Pyrroles|Benzodiazepine|NADPH|*Catalysis|Prodrugs 191 GLRX 30760648 Aging (Albany NY) 2019 PMC6382415 10.18632/aging.101822 5 1 0 415 *Cancer Stem Cells|Gene Expression Regulation, Neoplastic|Oncogenesis|Signal Transduction|Tumor|Up-Regulation 191 GLRX 30703479 Free Radic. Biol. Med. 2019 10.1016/j.freeradbiomed.2019.01.037 4 9 0 415 *Vitamin K 3|*Ascorbic Acid|*Oxidative Stress|*Cell Death|*DNA Replication|Oxidation-Reduction|Thioredoxins|Hydrogen Peroxide|Reactive Oxygen Species|*Cancer 191 GLRX 30682073 PLoS ONE 2019 PMC6347181 10.1371/journal.pone.0210827 2 10 0 415 Mice|Animals|GLRX protein, human|*Glutaredoxins|Il33 protein, mouse|IL33 protein, human|*Interleukin-33|*Signal Transduction|Tifab protein, human|TRAF6|Lipopolysaccharides|NF-kappa B|Toll-Like Receptor 4|Macrophages|Inflammation|Cytokines|RAW 264.7 Cells|Lungs|Protein Processing, Post-Translational|Mice, Knockout 191 GLRX 30661098 J. Cancer Res. Clin. Oncol. 2019 10.1007/s00432-019-02845-y 2 8 0 415 Humans|*Nonsmall Cell Lung Cancer|Lung Cancer|GLRX protein, human|*Glutaredoxin|Gefitinib|*Signal Transduction|ErbB Receptors|Quinazolines|Drug Resistance, Neoplasm|Protein Kinase Inhibitors|Cell Line, Tumor|Cell Proliferation|Apoptosis|Xenograft Model Antitumor Assays|Mutations|FOXM1 protein, human|Forkhead Box Protein M1|EGFR protein, human 191 GLRX 30598505 J. Biol. Chem. 2019 PMC6393595 10.1074/jbc.RA118.006096 3 5 0 415 GLRX protein, human|*Glutaredoxins|*Neutrophils|*Bone Marrow|*Integrins|*Up-Regulation|Integrin alpha4|Vascular Cell Adhesion Molecule-1|*Transcriptional Activation|Cell Movement|Reactive Oxygen Species 191 glycolisis 30880247 Free Radic. Biol. Med. 2019 10.1016/j.freeradbiomed.2019.03.009 10 1 0 0 *Nonsmall Cell Lung Cancer|*Cisplatin|Lung Cancer|*Reactive Oxygen Species|Drug Resistance, Neoplasm|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Signal Transduction|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha 23 GOLGA3 31728975 Methods Mol. Biol. 2019 10.1007/978-1-4939-9904-0_18 0 0 0 189 *Urinary Bladder Neoplasms|*RNA|RNA, Neoplasm|RNA Splicing|Gene Fusion|Sequencing, RNA|Gene Expression Regulation, Neoplastic|*Chimera|Bioinformatics|*Rare Diseases 46 GOLGA3 30818082 Int. J. Biochem. Cell Biol. 2019 10.1016/j.biocel.2019.02.007 4 0 0 189 *Urinary Bladder Neoplasms|*Urinary Bladder|Gene Fusions|*RNA|Sequence Analysis, RNA|RNA, Neoplasm|*Carcinoma, Transitional Cell|RNA Splicing|Computational Biology|Oncogene Proteins, Fusion 46 GOLGA3 30695072 PLoS ONE 2019 PMC6351060 10.1371/journal.pone.0211501 2 22 0 189 GDNF protein, human|*Glial Cell Line-Derived Neurotrophic Factor|*Golgi Matrix Proteins|*Golgi Apparatus|*Cell Migration|*Microtubule|Glioma|GOLPH3 protein, human|*Membrane Proteins|*Microtubule-Associated Proteins|Cell Line, Tumor|*Neoplastic Processes 46 GPR158 31749686 Front Cell Neurosci 2019 PMC6843000 10.3389/fncel.2019.00465 0 0 0 90 Pyramidal Cells|CA1 Region, Hippocampal|Synapses|Neuronal Plasticity|Hippocampus|Synaptic Transmission|Maze Learning 33 GPR158 31602702 Exp. Dermatol. 2019 10.1111/exd.14047 0 0 0 90 33 GPR158 31546163 Forensic Sci. Int. 2019 10.1016/j.forsciint.2019.109944 1 0 0 90 Humans|Infant, Newborn|Infant|Child, Preschool|Child|Adolescent|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|*DNA Methylation|*B-DNA|CpG Islands|Forensic Genetics|Markers, DNA|Sequence Analysis, DNA|Aging|DNA Microarrays|Linear Models 33 GPR158 31533654 BMC Cancer 2019 PMC6751742 10.1186/s12885-019-6084-4 2 0 0 90 Humans|Female|*Prognosis|*Ovarian Cancer|Adenocarcinoma, Clear Cell|Cystadenocarcinoma, Serous|Carcinoma, Ovarian Epithelial|Carcinoma, Endometrioid|Adenocarcinoma, Mucinous|Biomarkers, Tumor|Ovary|Survival Rates|Tumor Suppressor Protein p53|COL3A1 protein, human|Collagen Type III 33 GPR158 31515243 Pharmacol. Rev. 2019 PMC6742926 10.1124/pr.119.018044 1 8 0 90 United States|ADGRE5 protein, human|G-Protein-Coupled Receptors|*Ligands|metabotropic glutamate receptor 8|Receptors, Metabotropic Glutamate|ADGRG1 protein, human|metabotropic glutamate receptor 7|metabotropic glutamate receptor 6|*Cell Membrane|metabotropic glutamate receptor 4|Binding Sites|Signal Transduction|Models, Molecular|Antigens, CD 33 GPR158 31311860 J. Biol. Chem. 2019 PMC6721952 10.1074/jbc.RA119.007533 1 7 0 90 Mice|Animals|*Potassium Channel|RGS7 protein, human|*RGS Proteins|*Receptors, G-Protein-Coupled|*Pyramidal Neurons|Signal Transduction|Cortex, Prefrontal|Neurons|Protein Kinase A|Rgs7 protein, mouse|GPR158 protein, mouse 33 GPR158 31204315 Mol. Cell Proteomics 2019 PMC6683007 10.1074/mcp.RA119.001604 0 0 0 90 Animals|Rats|*Parkinson Disease|*Traumatic Brain Injury|Brain|Rats, Sprague-Dawley|Cerebral Cortex|Biomarkers|*Experimental Model 33 GPR158 31189666 Mol. Pharmacol. 2019 10.1124/mol.118.113019 0 4 0 90 Humans|GPRC5C protein, human|*Receptors, G-Protein-Coupled|RGS Proteins|GTP-Binding Protein alpha Subunits, Gi-Go|*Ligands|Signal Transduction|HEK293 Cells 33 GPR158 30855200 J Ocul Pharmacol Ther 2019 PMC6533807 10.1089/jop.2018.0135 0 0 0 90 33 GPR174 31875850 Nature 2019 10.1038/s41586-019-1873-0 3 0 0 18 Mice|Male|Animals|*Immunity, Humoral|*Sex Characteristics|CCL21 protein, human|*Chemokine CCL21|Germinal Center|B-Lymphocytes|Mice, Inbred C57BL|Cell Movement|GPR174 protein, mouse|Receptors, G-Protein-Coupled 26 GPR174 31786099 Int. Immunopharmacol. 2019 10.1016/j.intimp.2019.106034 0 0 0 18 Mice|Animals|*B Cells|*Sepsis|Cecum|Mice, Knockout|*Lymphoid Tissue|Spleen|Ligation|GPR174 protein, mouse|Receptors, G-Protein-Coupled 26 GPR174 30850582 Cell Death Dis 2019 PMC6408576 10.1038/s41419-019-1462-z 1 17 0 18 Mice|Animals|*T-Lymphocytes, Regulatory|*Cytokines|IL10 protein, human|Interleukin-10|Lipopolysaccharides|Macrophages|Sepsis|Tumor Necrosis Factor-alpha|Interleukin-6|Macrophages, Peritoneal|Cecum|CTLA4 protein, human|Cytotoxic T-Lymphocyte-Associated Antigen 4|Spleen|Disease Models, Animal|GPR174 protein, mouse|Receptors, G-Protein-Coupled 26 GPR179 31619966 Front Cell Neurosci 2019 PMC6760018 10.3389/fncel.2019.00423 0 0 0 5 Mice|Animals|*Retinal Bipolar Cells|*Retina|Synapses|Retinal Rod Photoreceptor Cells|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|Dendrites|Axons|Electron Microscopy|Glutamate 25 GPR179 31515243 Pharmacol. Rev. 2019 PMC6742926 10.1124/pr.119.018044 1 8 0 5 United States|ADGRE5 protein, human|G-Protein-Coupled Receptors|*Ligands|metabotropic glutamate receptor 8|Receptors, Metabotropic Glutamate|ADGRG1 protein, human|metabotropic glutamate receptor 7|metabotropic glutamate receptor 6|*Cell Membrane|metabotropic glutamate receptor 4|Binding Sites|Signal Transduction|Models, Molecular|Antigens, CD 25 GPR179 30825406 Hum. Mutat. 2019 10.1002/humu.23735 1 0 0 5 Humans|Night blindness, congenital stationary|Night Blindness|Eye Diseases, Hereditary|Genetic Diseases, X-Linked|Myopia|*Retina|*Retinal Diseases|*Introns|Electroretinography|Exome|Pedigree|*Silent Mutation|Calcium Channels, L-Type|Phenotype|Mutation|Base Sequence|CACNA1F protein, human 25 GPR26 31633210 Anim. Genet. 2019 10.1111/age.12864 1 0 0 71 Swine|Animals|*Quantitative Trait Loci|*Meat|*Genotype|Sus scrofa|Genome-Wide Association Study|SNPs|Muscle, Skeletal|Phenotype|Thigh|*Electric Conductivity 20 gpr34 31823199 Mol. Neurobiol. 2019 10.1007/s12035-019-01831-2 0 1 0 33 Male|Humans|Animals|Rats|*Cannabidiol|*Ketamine|*Rats, Sprague-Dawley|*Schizophrenia|Antipsychotic Agents|Cortex, Prefrontal|*Cognitive Impairment|Brain|Hippocampus|Disease Models, Animal 42 gpr34 30975169 J Neuroinflammation 2019 PMC6458787 10.1186/s12974-019-1458-8 2 0 0 33 Animals|*Microglia|*Pain, Neuropathic|Hyperalgesia|Spinal Cord|Peripheral Nerve Injuries|Disease Models, Animal|Macrophage Activation|Microfilament Proteins 42 GPR64 31502283 Ann. N. Y. Acad. Sci. 2019 PMC7236788 10.1111/nyas.14227 1 0 0 39 Humans|*Arrestins|*Signal Transduction|ADGRG1 protein, human|G-Protein-Coupled Receptors|beta-Arrestins|Endocytosis|Protein Transport|Endosomes|Cell Movement|HEK293 Cells|GPR64 protein, human 28 GPR64 31412816 BMC Cancer 2019 PMC6694613 10.1186/s12885-019-5998-1 1 0 0 39 Humans|Female|*Endometrial Cancer|Carcinoma, Endometrioid|*Genes, Tumor Suppressor|Neoplasm Invasiveness|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|RNA, Small Interfering|RNA, Messenger|GPR64 protein, human 28 GPR85 31313401 Mol. Carcinog. 2019 PMC6721979 10.1002/mc.23084 0 6 0 29 Mice|Animals|*Receptor, Cholecystokinin B|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|Carcinoma in Situ|Genes, ras|Mice, Transgenic|Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic|Disease Progression|Cell Line, Tumor|YF 476|Phenylurea Compounds|Benzodiazepinones|*Chemoprevention 25 GRID1 31858623 Reprod. Domest. Anim. 2019 10.1111/rda.13608 0 0 0 73 Horses|Animals|*Genome|*Genomics|*Phenotype|Breeding|*Reproduction|Selection, Genetic|Polymorphism, Single Nucleotide|Sequence Analysis 36 GRID1 31738830 Blood Adv 2019 PMC6880887 10.1182/bloodadvances.2019000922 0 2 0 73 Humans|Adult|*Genome-Wide Association Study|*Myelodysplastic Syndromes|Mutations|Bone Marrow Cells|Genomics|Immunity, Innate|EYA2 protein, human|Nuclear Proteins|Protein Tyrosine Phosphatases|Intracellular Signaling Peptides and Proteins 36 GRIN3A 31743624 Autism Res 2019 10.1002/aur.2240 2 1 0 202 Humans|Animals|Mice|Adolescent|*Autistic Disorder|Autism Spectrum Disorder|*Transcriptome Analyses|Brain|Transcriptome|Disease Models, Animal|GABRA2 protein, human|Receptors, GABA-A|Gabra2 protein, mouse 70 GRIN3A 31277281 Int J Mol Sci 2019 PMC6651230 10.3390/ijms20133273 0 2 0 202 Animals|Rats|*Receptors, N-Methyl-D-Aspartate|*Nitric Oxide|*Sleep Deprivation|*Rats, Wistar|*Cerebral Cortex|Nitric Oxide Synthase|*Brain|*Aging|Nitric Oxide Synthase Type I|*Signal Transduction|Neurons 70 GRIN3A 31061112 Proc. 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Neurol. 2019 10.1016/j.expneurol.2019.112978 4 0 0 80 Animals|Mice|*bcl-2-Associated X Protein|*Ischemia-Reperfusion Injury|*Neuroprotection|Brain Ischemia|EPO protein, human|Erythropoietin|Infarction, Middle Cerebral Artery|Neuroprotective Agents|RECS1 protein, mouse|*Membrane Proteins|Apoptosis|epothilone B|*Epothilones|Stroke|Brain|Epoetin Alfa 74 GRINA 30991297 Cell Calcium 2019 10.1016/j.ceca.2019.04.002 1 1 0 80 Humans|Animals|Calcium Channels, N-Type|GTP-Binding Protein beta Subunits|Membrane Proteins|Unfolded Protein Response|Signal Transduction|HEK293 Cells|Receptors, N-Methyl-D-Aspartate 74 GRINA 30845727 Cells 2019 PMC6468776 10.3390/cells8030219 3 2 0 80 Humans|*Periodontal Ligament|*Stem Cells|Cell Differentiation|Osteogenesis|Cells, Cultured|Cell Proliferation|*Ligaments|*Ion Channel|Neurons 74 GRINA 30730609 2019 PMC6790675 10.1002/art.40849 0 0 0 80 *Quantitative Trait Loci|*Osteoarthritis|Alleles|CpG Islands|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|DNA Methylation|Cartilage, Articular|*Risk Factors 74 GRINA 30726424 Rev Peru Med Exp Salud Publica 2019 10.17843/rpmesp.2018.354.3892 0 0 0 80 Humans|*Sociobiology|*Information Theory|Biological Evolution 74 GRINA 30685393 Schizophr. Res. 2019 10.1016/j.schres.2019.01.007 1 1 0 80 Humans|*Gliadin|*N-Methylaspartate|*Glutamate|*Gastrointestinal Microbiome|*Schizophrenia|Celiac Disease|Immunoglobulin A|*Permeability|Immunoglobulin G|*Synapsins|Inflammation 74 GSDMB 31628657 Adv. Exp. Med. Biol. 2019 10.1007/978-981-13-9367-9_9 2 0 0 64 Humans|Mice|Animals|*Pyroptosis|Caspases|Inflammasomes|Neoplasm Proteins|Cell Death|Cardiolipin|Proteolysis|Phosphatidylinositol Phosphates|Serine, Phosphatidyl|Protein Processing, Post-Translational|GSDMA protein, human|GSDMD protein, human 108 GSDMB 31560728 PLoS ONE 2019 PMC6764692 10.1371/journal.pone.0223212 0 1 0 64 Humans|Mice|Animals|Genome-Wide Association Study|*Circadian Clocks|Alleles|Genetic Predisposition to Disease|Asthma|Polymorphism, Single Nucleotide|Membrane Proteins|DNA Methylation|Promoter Regions, Genetic|Neoplasm Proteins|Genotype|Egg Proteins|Phenotype|Gene Expression|Regulatory Sequences, Nucleic Acid|Lungs|ORMDL3 protein, human|ZPBP2 protein, human 108 GSDMB 31455540 Meth. Enzymol. 2019 10.1016/bs.mie.2019.04.024 0 0 0 64 Humans|Animals|Pyroptosis|Caspases|Inflammasome|Neoplasm Proteins|Cell Membranes|Cell Death|Cytokines|Inflammation|Liposome|GSDMA protein, human|GSDMD protein, human 108 GSDMB 31441980 Clin. Exp. Allergy 2019 PMC6899469 10.1111/cea.13485 2 0 0 64 Child|Humans|*Rhinitis|*Eczema|*Hypersensitivity|*Respiratory Sounds|Asthma|Allergens 108 GSDMB 31332973 Allergy Asthma Immunol Res 2019 PMC6658410 10.4168/aair.2019.11.5.604 1 0 0 64 *Airway Remodeling|*Asthma|*Respiratory Physiological Phenomena|Leukotriene Antagonists|Lung|Muscle, Smooth|Inflammation|Mucus|Epithelial Cells|Hyperplasia 108 GSDMB 31090575 Curr. Opin. Pediatr. 2019 10.1097/MOP.0000000000000758 1 0 0 64 Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asthma|Genetic Loci|Genotype|Case-Control Studies|Membrane Proteins 108 GSDMB 31064780 Clin. Cancer Res. 2019 10.1158/1078-0432.CCR-18-2381 1 0 0 64 Trastuzumab|Receptor, ErbB-2|Drug Resistance, Neoplasm|Neoplasm Proteins|Cell Line, Tumor|Antibodies, Monoclonal|Antibodies, Monoclonal, Humanized|Gene Expression Regulation, Neoplastic|Cell Migration|*Cytoplasm 108 GULP1 31516309 Mol. Vis. 2019 PMC6706170 1 2 0 148 Humans|*Trabecular Meshwork|*Proteomics|Glucocorticoid|Dexamethasone|*Phagocytosis|*Genomics|Signal Transduction|Integrin alphaVbeta3|Cells, Cultured|Glaucoma|Cell Line 37 GULP1 31409653 J. Cell Biol. 2019 PMC6781437 10.1083/jcb.201901032 2 0 0 148 Animals|*Ephrins|Receptors, Eph Family|Signal Transduction|Guanine Nucleotide Exchange Factor|Adaptor Proteins, Signal Transducing|Cultured Cells|*Biochemical Phenomena 37 GULP1 31373844 FASEB J. 2019 PMC6902715 10.1096/fj.201802825RR 1 9 0 148 Humans|Cricetinae|Animals|*Phosphorylation|*Threonine|PKC-3 protein|Amyloid beta-Protein Precursor|*Protein Kinase C|Alzheimer Disease|Amyloid beta-Peptides|*Amyloidogenic Proteins|Amyloid Precursor Protein Secretases|*Amyloidosis|Protein Processing, Post-Translational|*Protein Domains|Cricetulus|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing|Nuclear Proteins|CHO Cells|HEK293 Cells 37 GULP1 31301364 Biochim Biophys Acta Mol Cell Res 2019 10.1016/j.bbamcr.2019.07.003 0 3 0 148 *Phagocytosis|Phagosomes|Phagocytes|rac1 GTP-Binding Protein|rac GTP-Binding Proteins|cdc42 GTP-Binding Protein|Macrophages|F-Actin|phosphatidylserine receptor|Receptors, Cell Surface|GTPase Activating Protein|Cell Line|Cytoskeleton|*Protein Structure, Secondary|Downregulation 37 GULP1 31300465 Biochem. J. 2019 10.1042/BCJ20180840 1 7 0 148 Amyloid beta-Protein Precursor|Alzheimer Disease|Monomeric Clathrin Assembly Proteins|Amyloid beta-Peptides|*Endocytosis|*Adaptor Proteins, Signal Transducing|Amyloid Plaques|Peptide Fragments|Proteolysis|Cell Nucleus 37 GULP1 31094033 Mol. Reprod. Dev. 2019 10.1002/mrd.23158 1 0 0 148 Humans|Female|*RNA, Long Noncoding|*Primary Ovarian Insufficiency|*Menopause, Premature|Ovary|Gene Expression Profiling|RNA, Messenger|Upregulation|Downregulation|*Menstrual Cycle|Sequencing, Next-Generation|Signal Transduction 37 gusa 31788711 Appl. Microbiol. Biotechnol. 2019 10.1007/s00253-019-10223-4 1 0 0 0 *Gene Editing|*CRISPR-Cas Systems|*Actinomycetes|*Actinomyces|*CRISPR|Streptomyces coelicolor|Plasmid|Genome, Bacterial|Genetic Engineering|Gene Expression Regulation, Bacterial|Streptomyces|Gene Cluster 576 gusa 31776766 Planta 2019 10.1007/s00425-019-03298-w 1 1 0 0 *Lavandula|pinene cyclase I|Escherichia coli|*Intramolecular Lyases|linalool|Monoterpenes|Gene Expression Regulation, Plant|Alkyl and Aryl Transferases|Plant Proteins|Tobacco|Transcription Factors|Plant Leaves|Oils, Volatile|Cloning, Molecular|Cineole|Promoter Regions, Genetic|3'-(1-butylphosphoryl)adenosine 576 gusa 31703352 Genes (Basel) 2019 PMC6895784 10.3390/genes10110901 2 0 0 0 Humans|*Genomics|*DNA Replication|Recombination, Genetic|Genome, Fungal|Candida albicans|*Cell Division 576 gusa 31595725 J Zhejiang Univ Sci B 2019 PMC6825808 10.1631/jzus.B1900270 1 0 0 0 *Streptomyces rimosus|Streptomyces|Gene Expression Regulation, Bacterial|Promoter Regions, Genetic|Bacterial Proteins|Genetic Engineering 576 gusa 31253141 Microb. Cell Fact. 2019 PMC6599336 10.1186/s12934-019-1162-5 3 0 0 0 *Acarbose|*Actinoplanes|Micromonosporaceae|Proteome|Multigene Family|Bacterial Proteins|Transcriptome 576 gusa 31182805 Sci Rep 2019 PMC6557892 10.1038/s41598-019-44640-2 0 0 0 0 *Metagenome|Integrons|Antibiotic Resistance|Open Reading Frames|Promoter Regions, Genetic|Polymerase Chain Reaction 576 gusa 31091755 Int J Mol Sci 2019 PMC6566926 10.3390/ijms20102389 2 0 0 0 *Triticum|*Aquaporins|Gene Expression Regulation, Plant|Plant Proteins|Plants, Genetically Modified|Salt Tolerance|Droughts|Stress, Physiological|Tobacco|Plant Roots|Sodium Chloride 576 gusa 31065250 Front Microbiol 2019 PMC6489563 10.3389/fmicb.2019.00768 2 0 0 0 *Rhizobium|*Trifolium|Rhizobium leguminosarum|Nitrogen Fixation|Symbiosis|Legumes|Soil Microbiology 576 gusa 30814871 Turk. J. Biol. 2019 PMC6353253 10.3906/biy-1706-6 1 0 0 0 *Dendrimers|*Medicago sativa|*Gene Transfer Techniques|diethylenetriamine|Polyamines|Poly(amidoamine)|Transfection|*Nanoparticles|*Genetic Therapy|DNA|Particle Size|Plasmids|Cell Line, Tumor|Cell Survival 576 GZMA 31756926 Cancers (Basel) 2019 PMC6966682 10.3390/cancers11121824 1 0 0 426 Humans|*Carcinoma, Hepatocellular|*Progression-Free Survival|*Liver Neoplasms|*Immunotherapy|Antigens, Neoplasm|Class I Major Histocompatibility Molecules|Mutations|Sequencing, RNA|Genome|*Immunologic Factors|T-Lymphocytes 379 GZMA 31736981 Front Immunol 2019 PMC6834543 10.3389/fimmu.2019.02579 0 0 0 426 Animals|GZMM protein, human|GZMA protein, human|GZMB protein, human|*Granzymes|Phylogeny|Sea Bass|Gilthead Seabream|Nodaviridae|Head Kidney|*Cytotoxicity, Immunologic|Fish Diseases|Leukocytes|Immunity, Innate|Lymphocytes 379 GZMA 31646075 Oncoimmunology 2019 PMC6791424 10.1080/2162402X.2019.1629780 1 1 0 426 Humans|Neoplasm Recurrence, Local|*Genes, MHC Class I|*HLA-B|Molecules, MHC-I|Disease-Free Survival|Lymphocyte Activation|Mutations|*Breast Cancer|HLA-A Antigens 379 GZMA 31548399 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6789640 10.1073/pnas.1905762116 0 0 0 426 Animals|Mice|IL17A protein, human|IL-17|Encephalomyelitis, Autoimmune, Experimental|Th1 Cells|Th17 Cells|CD4-Positive T-Lymphocytes|Interferon-gamma|Granulocyte-Macrophage Colony-Stimulating Factor|Mice, Knockout|*Encephalitis|Mice, Inbred C57BL 379 GZMA 31534011 Mol. Cancer Ther. 2019 10.1158/1535-7163.MCT-18-0986 1 0 0 426 Mice|Animals|CD274 protein, human|*B7-H1 Antigen|*Urinary Bladder Neoplasms|*Programmed Cell Death 1 Receptor|*Mice, Inbred C57BL|Immunotherapy|Antibodies, Monoclonal|Combined Modality Therapy|Cell Line, Tumor|Tumor Microenvironment|*Immunologic Factors 379 GZMA 31431980 Rheumatol Adv Pract 2019 PMC6649940 10.1093/rap/rky043 1 0 0 426 *Programmed Cell Death 1 Receptor|T-Lymphocytes, Helper-Inducer|Receptors, CXCR5|CD4-Positive T-Lymphocytes|Flow Cytometry 379 GZMA 31390578 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109264 3 0 0 426 *Carcinoma, Renal Cell|*Computational Biology|Kidney Neoplasms|Prognosis|CXCL13 protein, human|*Chemokine CXCL13|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Gene Regulatory Networks|Protein Interaction Maps 379 GZMA 31326139 Hum. Immunol. 2019 10.1016/j.humimm.2019.07.283 2 0 0 426 Natural Killer Cells|CD56 Antigen|Cytotoxicity, Immunologic|Perforin|Granzymes|Lymphocyte Activation|Receptors, IgG|Interferon-gamma|*Neural Cell Adhesion Molecules 379 GZMA 31321514 J. Neurol. 2019 10.1007/s00415-019-09476-w 0 1 0 426 Genome-Wide Association Study|*Multiple Sclerosis|*Epigenetic|Quantitative Trait Loci|Genetic Predisposition to Disease|DNA Methylation|Mendelian Randomization Analysis|Epigenesis, Genetic|Phenotype|Genomics 379 GZMA 31293597 Front Immunol 2019 PMC6606709 10.3389/fimmu.2019.01450 2 8 0 426 GZMB protein, human|GZMA protein, human|*Granzymes|*Dendritic Cells|Type I Interferon|Toll-Like Receptor 9|*Adaptive Immunity|Oligodeoxyribonucleotides|Adjuvants, Immunologic|Cytokines|Antigen 379 GZMK 31736981 Front Immunol 2019 PMC6834543 10.3389/fimmu.2019.02579 0 0 0 54 Animals|GZMM protein, human|GZMA protein, human|GZMB protein, human|*Granzymes|Phylogeny|Sea Bass|Gilthead Seabream|Nodaviridae|Head Kidney|*Cytotoxicity, Immunologic|Fish Diseases|Leukocytes|Immunity, Innate|Lymphocytes 71 GZMK 31563951 Brain 2019 10.1093/brain/awz301 3 0 0 54 Humans|*Transendothelial and Transepithelial Migration|*Granzyme K|Endothelial Cells|Leukocytes, Mononuclear|ICAM1 protein, human|Intercellular Adhesion Molecule-1|CD4-Positive T-Lymphocytes|*Effector B Cells|Blood-Brain Barrier|Multiple Sclerosis|*Immunologic Surveillance|Brain|Central Nervous System|Th17 Cells|Natalizumab|*Memory|VLA-4|Lymphocyte Function-Associated Antigen-1 71 GZMK 31439037 J Immunother Cancer 2019 PMC6704567 10.1186/s40425-019-0665-2 0 2 0 54 Humans|*Neoplasms|*Antibodies, Monoclonal|Programmed Cell Death 1 Receptor|Antineoplastic Agents, Immunological|Antibodies, Monoclonal, Humanized|Treatment Outcome 71 GZMK 31061532 Nat. Immunol. 2019 PMC6602051 10.1038/s41590-019-0378-1 40 0 0 54 Humans|*Transcriptome|*Synovial Membrane|*Rheumatoid Arthritis|Synovia|Fibroblasts|Osteoarthritis|Cytokines|Cells, Cultured|Flow Cytometry|Thy-1 Antigens|T Cells 71 GZMK 30873621 J. Cell. Physiol. 2019 10.1002/jcp.28323 2 2 0 54 Mice|Animals|*Myocardial Reperfusion Injury|*Sevoflurane|*Granzyme K|Ischemic Postconditioning|Myocardium|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Apoptosis|Downregulation|Methyl Ethers|CASP3 protein, human|Caspase 3|Cardiomyocytes|MicroRNAs|Signal Transduction|Upregulation|Myocardial Infarction|Protective Agents 71 GZMK 30621359 J Clin Med 2019 PMC6352223 10.3390/jcm8010050 5 0 0 54 Humans|*Diagnosis, Differential|Bayes Theorem|*Rheumatoid Arthritis|*Osteoarthritis|Synovial Membrane|Oligonucleotide Array Sequence Analysis|Transcriptome|*Genetic Markers|*Intelligence 71 H6PD 31803243 Front Genet 2019 PMC6872681 10.3389/fgene.2019.01174 0 0 0 587 Dogs|Animals|Humans|*Polymorphism, Single Nucleotide|*Genome|Breeding|Linkage Disequilibrium|Genetics, Population|Selection, Genetic|Genetic Variation|Genotype|Homozygote|*Chinese|Genomics|China|Mongolia|Kazakhstan 65 H6PD 31738135 Curr Cancer Drug Targets 2019 10.2174/1568009619666191116095847 0 0 0 587 Humans|*MCF-7 Cells|*Hypoxia|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|Glycolysis|Cell Hypoxia|Signal Transduction|Reactive Oxygen Species|Glucose 65 H6PD 31558916 Diabetol Metab Syndr 2019 PMC6755690 10.1186/s13098-019-0474-2 0 1 0 587 Humans|Female|11 beta-Hydroxysteroid Dehydrogenase Type 1|galactose-6-phosphate dehydrogenase|Carbohydrate Dehydrogenases|Metabolic Syndrome|Obesity|Polycystic Ovary Syndrome|Genotype 65 H6PD 30909744 Int J Hyperthermia 2019 10.1080/02656736.2019.1578420 0 0 0 587 Humans|*Papillomavirus Infections|*Keratinocytes|*Proteomics|*Computational Biology|*Hyperthermia, Induced|*Condylomata Acuminata|*Cell Differentiation 65 H6PD 30737636 J Nucl Cardiol 2019 10.1007/s12350-019-01618-x 4 1 0 587 Doxorubicin|Liposomes|Neuroblastoma|Immunoglobulin Fab Fragments|*Myocardium 65 H6PD 30617965 Eur. J. Nucl. Med. Mol. Imaging 2019 10.1007/s00259-018-4254-2 4 0 0 587 *Fluorodeoxyglucose F18|*Endoplasmic Reticulum|Positron-Emission Tomography|*Biological Transport|Glucose|*Brain|Carbohydrate Dehydrogenases|*Biochemical Phenomena 65 HABP2 31698750 Cells 2019 PMC6912458 10.3390/cells8111396 0 5 0 315 *Vascular Endothelial Growth Factor A|*Neovascularization, Pathologic|Neovascularization, Physiologic|Laminin|Cell Movement|Proteoglycans|Cell Proliferation|Human Umbilical Vein Endothelial Cells|Collagen|Cells, Cultured|Signal Transduction 150 HABP2 31479940 Thromb. Res. 2019 10.1016/j.thromres.2019.08.016 2 2 0 315 Humans|*Factor VII|*Fluorescent Dyes|Serine Endopeptidases|Histones|*Blood Coagulation Tests|arginyllysine|Dipeptides|Genotype|Active Site|prolylarginine|*Plasma 150 HABP2 31407948 Ups. J. Med. Sci. 2019 PMC6758637 10.1080/03009734.2019.1645248 0 2 0 315 150 HABP2 31247975 Genes (Basel) 2019 PMC6678600 10.3390/genes10070482 3 0 0 315 Humans|*Risk Factors|*Thyroid Cancer, Papillary|Thyroid Cancer|Carcinoma, Papillary|Cowden Syndrome|Familial Adenomatous Polyposis|Thyroid Gland|Genetic Predisposition to Disease|Gardner Syndrome|Carney Complex|Syndrome, Werner|*Germ Line 150 HABP2 30826992 Endocrine 2019 10.1007/s12020-019-01878-0 1 0 0 315 Humans|*Thyroid Cancer, Papillary|Thyroid Neoplasms|Carcinoma, Papillary|Genetic Predisposition to Disease|*Sequencing, Next-Generation|Polymorphism, Single Nucleotide|Genotype|Telomerase|Mutation|*Germ Line 150 HABP2 30654737 BMC Evol. Biol. 2019 PMC6337849 10.1186/s12862-019-1353-z 5 0 0 315 Animals|Humans|*Chordates|Urokinase-Type Plasminogen Activator|Plasminogen Activator Inhibitor 1|Plasmin|Amino Acid Sequence|Serine Endopeptidases|Plasminogen 150 HAVCR1 31885544 Gastroenterol Res Pract 2019 PMC6914876 10.1155/2019/6746970 0 0 0 889 Humans|HAVCR1 protein, human|*Hepatitis A Virus Cellular Receptor 1|*MAP Kinase Signaling System|*Stomach Neoplasms|*Adenocarcinoma|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Cell Proliferation|Cell Movement|*Neoplastic Processes|Gene Knockdown Techniques|Upregulation|Disease Progression|RNA, Messenger 814 HAVCR1 31884094 Life Sci. 2019 10.1016/j.lfs.2019.117217 1 0 0 889 Rats|Animals|fraxin|*Acute Kidney Injury|*Ischemia-Reperfusion Injury|*Kidney|*Coumarins|Oxidative Stress|Malondialdehyde|Creatinine|Antioxidants|Rats, Sprague-Dawley|Superoxide Dismutase|*Reperfusion|*Ischemia|Disease Models, Animal 814 HAVCR1 31881660 Int J Mol Sci 2019 PMC6982095 10.3390/ijms21010155 1 0 0 889 Mice|Animals|*Autophagy|Autophagy-Related Protein 7|*Apoptosis|*Kidney|*Epithelial Cells|Autophagosome|Kidney Tubules, Proximal|Acute Kidney Injury|Microtubule-Associated Proteins|Knockout Mouse|Cell Line 814 HAVCR1 31830606 Ecotoxicol. Environ. Saf. 2019 10.1016/j.ecoenv.2019.110052 1 7 0 889 Male|Mice|Animals|*Cadmium|NPS R-467|*ICR Mouse|*Autophagy|*Protective Agents|*Aniline Compounds|*Kidney|Tubule, Proximal Renal|Calcium-Sensing Receptor|Apoptosis|Epithelial Cells|Kidney Diseases|Signal Transduction|Upregulation|*Corticosterone 814 HAVCR1 31793871 Clin. Nephrol. 2019 10.5414/CN109763 0 0 0 889 Humans|*Chronic Kidney Disease|Chronic Kidney Disease-Mineral and Bone Disorder|Parathyroid Hormone|Glomerular Filtration Rate|Fibroblast Growth Factors|HAVCR1 protein, human|*Hepatitis A Virus Cellular Receptor 1|Glucuronidase|Creatinine|Vitamin D|Phosphates|Calcium|Phosphorus|Biomarkers 814 HAVCR1 31793232 Congenit Heart Dis 2019 PMC6952564 10.1111/chd.12862 0 0 0 889 Humans|Young Adult|*Biomarkers|Hepatitis A Virus Cellular Receptor 1|Lipocalin-2|Creatinine|Insulin-Like Growth Factor Binding Proteins|*Heart Defects, Congenital|*Kidney|Acute Kidney Injury|Tissue Inhibitor of Metalloproteinase-2|Fatty Acid-Binding Proteins|Risk Assessment 814 HAVCR1 31677874 Environ. Pollut. 2019 PMC7307380 10.1016/j.envpol.2019.113334 1 0 0 889 Child|Infant|Infant, Newborn|Humans|Child, Preschool|glyphosate|LCN2 protein, human|Neutrophil Gelatinase-Associated Lipocalin|Hepatitis A Virus Cellular Receptor 1|*Biomarkers|*Kidney|Creatinine|*Glycine|Acute Kidney Injury|Renal Insufficiency, Chronic|Risk Factors 814 HAVCR1 31661774 Molecules 2019 PMC6864713 10.3390/molecules24213876 0 7 0 889 Humans|Mice|Animals|syringin|*Acute Kidney Injury|*Protective Agents|Cisplatin|*Glucosides|*Phenylpropionates|RIPK3 protein, human|Receptor-Interacting Protein Serine-Threonine Kinases|HAVCR1 protein, human|Hepatitis A Virus Cellular Receptor 1|*Signal Transduction|Apoptosis|Kidney|Creatinine|CASP3 protein, human|Caspase 3|Urea Nitrogen, Blood|*Phosphorylation 814 HAVCR1 31652595 Int J Mol Sci 2019 PMC6834366 10.3390/ijms20205238 4 1 0 889 *Cisplatin|HAVCR1 protein, human|Hepatitis A Virus Cellular Receptor 1|*Acute Kidney Injury|*Kidney|*Biomarkers|Lipocalin-2|Antineoplastic Agents|Creatinine|Apoptosis 814 HAVCR1 31646460 Int Urol Nephrol 2019 10.1007/s11255-019-02311-1 0 0 0 889 Adult|Child|Humans|Aged|HAVCR1 protein, human|*Hepatitis A Virus Cellular Receptor 1|*Biomarkers|*Kidney|Receiver Operating Characteristic|Acute Kidney Injury|Area Under Curve|Creatinine|Lipocalin-2|Specificity|Biopsies|*Nephrectomy 814 HCP5 31849534 Cancer Manag Res 2019 PMC6913263 10.2147/CMAR.S230324 3 0 0 50 Humans|*RNA, Long Noncoding|*Carcinoma, Squamous Cell|*Epithelial-Mesenchymal Transition|*Oral Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Proliferation|Biomarkers, Tumor|SOX4 protein, human|SOXC Transcription Factors|Mirn140 microRNA, human 101 HCP5 31836918 Naunyn Schmiedebergs Arch. Pharmacol. 2019 10.1007/s00210-019-01788-y 0 3 0 50 *RNA, Long Noncoding|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Leukemia, Myeloid, Acute|shRNA|Cell Line, Tumor|Signal Transduction|*Disease Progression 101 HCP5 31746434 Oncol. Rep. 2019 10.3892/or.2019.7404 3 4 0 50 Humans|Male|*RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|3' Untranslated Region|Cell Line, Tumor|Prostate Cancer|*Prostatic Hyperplasia|Upregulation|Disease Progression|Prostate|Apoptosis 101 HEG1 31654571 Clin. Sci. 2019 10.1042/CS20190704 0 0 0 40 Humans|*Carcinoma, Hepatocellular|Epithelial-Mesenchymal Transition|*Liver Neoplasms|Neoplasm Invasiveness|Signal Transduction|Cell Movement|Gene Expression Regulation, Neoplastic|Hep G2 Cells|*Neoplastic Processes|Up-Regulation|Cell Line, Tumor|Prognosis|Membrane Proteins|HEG1 protein, human 37 HEG1 31278131 Clin. Sci. 2019 10.1042/CS20190225 2 5 0 40 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Epithelial-Mesenchymal Transition|Wnt Signaling Pathway|beta Catenin|*Catenins|Gene Expression Regulation, Neoplastic|Up-Regulation|*Neoplastic Processes|Cell Line, Tumor|Hep G2 Cells|Cell Movement|Neovascularization, Pathologic|Prognosis|HEG1 protein, human|Membrane Proteins 37 HEG1 31262974 Biosci. Rep. 2019 PMC6630026 10.1042/BSR20190634 1 0 0 40 Humans|*Lung Cancer|MicroRNAs|CCND1 protein, human|Cyclin D1|*Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Downregulation|Cell Movement|Cell Proliferation|Cell Line, Tumor|3' Untranslated Regions|Apoptosis|Real-Time Polymerase Chain Reaction|*Phenotypes 37 HEG1 30984245 Front Genet 2019 PMC6448551 10.3389/fgene.2019.00274 3 0 0 40 Swine|Animals|*Homozygote|Inbreeding|Genome|Genotype|Phenotype|Genetics, Population|Breeding|SNPs|Genomics|Chromosomes|Reproduction|*Disclosure 37 HEG1 30926747 J. Neurosci. 2019 PMC6538853 10.1523/JNEUROSCI.2671-18.2019 1 0 0 40 Mice|Animals|*Muscle Spindles|*Sensory Receptors|Mechanoreceptors|Proprioception|Muscle, Skeletal|Proprioceptive Feedback|*Phenotype|Tendon 37 HEG1 30642555 Lung Cancer 2019 10.1016/j.lungcan.2018.11.032 2 0 0 40 Humans|*Public Opinion|Mesothelioma, Malignant|*Mesothelioma|Pleural Neoplasms|*Lung Neoplasms|Prognosis|Immunohistochemistry|Peritoneal Neoplasms|Biomarkers, Tumor|Diagnosis, Differential|Biopsies|Canada 37 HELB 31139634 Front Cardiovasc Med 2019 PMC6527777 10.3389/fcvm.2019.00062 0 0 0 55 80 HES2 31775252 Metabolites 2019 PMC6950702 10.3390/metabo9120287 0 0 0 67 Humans|*Lyase, ATP Citrate|*Metabolome|Signal Transduction|Receptors, G-Protein-Coupled|Neovascularization, Pathologic|Cell Adhesion|Neovascularization, Physiologic|Human Umbilical Vein Endothelial Cells|Cell Proliferation|*Acyltransferases|Cancer|RNA, Small Interfering|ELTD1 protein, human|Slc25a1 protein, human|Mitochondrial Proteins|Anion Transport Proteins 55 HES2 31024328 Front Physiol 2019 PMC6460052 10.3389/fphys.2019.00272 0 1 0 67 Humans|*Glutathione|*Optogenetics|*Redox|Glutaredoxins|Cytosol|Mitochondria|Green Fluorescent Proteins|*Myocardium|Cardiomyocytes|Biosensing Techniques 55 HINT1 31848916 Mol. Biol. Rep. 2019 10.1007/s11033-019-05238-z 0 0 0 504 Humans|Russia|*Hereditary Motor and Sensory Neuropathies|Neuromyotonia|Charcot-Marie-Tooth Disease|Nerve Tissue Proteins|Mutation|HINT1 protein, human 193 HINT1 31832804 Neurogenetics 2019 10.1007/s10048-019-00591-4 0 0 0 504 Humans|*Charcot-Marie-Tooth Disease|*Whole Exome Sequencing|Mutations|Genotypes|GTP Phosphohydrolases|Pedigree|Phenotype|Mitochondrial Proteins|Heterogeneities, Genetic|Chinese|Diabetes Mellitus, Type 2|Cohort Studies|HINT1 protein, human|Nerve Tissue Proteins 193 HINT1 31604935 Nat Commun 2019 PMC6789022 10.1038/s41467-019-12710-8 0 0 0 504 *Second Messenger|Microphthalmia-Associated Transcription Factor|Systems, Signal Transduction|Mast Cells|Nerve Tissue Proteins|Transcriptional Activation|Protein Binding|Dinucleoside Phosphates 193 HINT1 31503445 ACS Chem Neurosci 2019 10.1021/acschemneuro.9b00432 0 2 0 504 Mice|Animals|*Nociception|*N-Methylaspartate|Receptors, Opioid, mu|Morphine|Receptors, N-Methyl-D-Aspartate|Analgesics, Opioid|Protein Kinase C|Signal Transduction|Nerve Tissue Proteins|Nitric Oxide Synthase Type I|Protein Binding|Nitric Oxide|*Inhibition, Psychological|Hint1 protein, mouse 193 HINT1 31400136 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.08.016 0 0 0 504 *Isaacs Syndrome|*Peripheral Nervous System Diseases|Hereditary Sensory and Motor Neuropathy|Nerve Tissue Proteins|Mutation|Pedigree 193 HINT1 31362466 Cells 2019 PMC6721544 10.3390/cells8080790 0 8 0 504 Animals|Mice|*Natural Killer Cells|Experimental Autoimmune Encephalomyelitis|*B Cells|Lymphocyte Activation|Myelin Proteolipid Protein|CD4-Positive T-Lymphocytes|Fluorescence Activated Cell Sorting|HSP70 Heat-Shock Proteins|Co-culture|Cells, Cultured|Cell Proliferation|Western Blot|Hint1 protein, mouse|Nerve Tissue Proteins 193 HINT1 31249525 Front Pharmacol 2019 PMC6582314 10.3389/fphar.2019.00634 2 8 0 504 *Ligands|sigma-1 receptor|Receptors, sigma|Calcium Channels|TRPV Cation Channels|Calcium|Nerve Tissue Proteins|*Cations 193 HINT1 31088288 Antioxid. Redox Signal. 2019 PMC6648240 10.1089/ars.2019.7724 0 5 0 504 193 HINT1 30772266 Biochem. Pharmacol. 2019 10.1016/j.bcp.2019.02.018 0 0 0 504 *Phosphorothioate Oligonucleotides|*Prodrugs|Adenosine Monophosphate|Hydrolysis 193 HINT2 31770197 Medicine (Baltimore) 2019 PMC6890357 10.1097/MD.0000000000017815 0 0 0 69 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Neoplasm Recurrence, Local|*Downregulation|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|mRNA|Real-Time PCR, Quantitative|Disease-Free Survival|Liver|Risk Factors|Hint2 protein, human|Mitochondrial Proteins 32 HINT2 31722709 Mol. Cancer 2019 PMC6854757 10.1186/s12943-019-1088-x 9 2 0 69 Animals|RNA Processing, Post-Transcriptional|Methylation|Methyltransferases|Adenosine|RNA, Messenger|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Disease Models, Animal 32 HINT2 31226805 Biology (Basel) 2019 PMC6628129 10.3390/biology8020049 1 3 0 69 prostacyclin synthetase|*Intramolecular Oxidoreductases|*Cytochrome P-450 Enzyme System|*Mass Spectrometry|Surface Plasmon Resonance|Prostaglandins 32 HINT2 30883840 Anim. Genet. 2019 10.1111/age.12772 0 0 0 69 Sheep|Animals|Iran|*Breeding|Sheep, Domestic|Haplotype|Phenotype|Genotype|Selection, Genetic|Linkage Disequilibrium|Genome Mapping|Polymorphism, Single Nucleotide|Homozygote 32 HINT2 30799275 Stem Cell Reports 2019 PMC6411484 10.1016/j.stemcr.2019.01.019 1 3 0 69 Mice|Animals|*Cellular Reprogramming|*Oocytes|Nuclear Transfer Techniques|Cloning, Organism|Blastocyst|Embryonic Development|*Cryopreservation|Embryo, Mammalian|Apoptosis|Cell Nucleus|Reactive Oxygen Species|Cytoplasm|Melatonin|Pluripotent Stem Cells 32 HINT2 30687385 Front Genet 2019 PMC6334744 10.3389/fgene.2018.00699 4 0 0 69 Sheep|Animals|*Genome|Genotype|Phenotype|Sheep, Domestic|Breeding|Polymorphism, Single Nucleotide|Livestock|Ethiopia|Middle East|Africa, Southern|Europe|China|Caribbean 32 HIVEP2 31602191 Mol Syndromol 2019 PMC6738162 10.1159/000499060 0 0 0 69 Child|Humans|Intellectual Disability|Developmental Disabilities|Sequencing, Whole Exome|Transcription Factors|Exome 77 HIVEP2 31586043 Transl Psychiatry 2019 PMC6778090 10.1038/s41398-019-0573-8 0 3 0 69 Male|Female|Rats|Humans|Animals|*Transcription Factor|*Dopamine|SLC6A3 protein, human|Dopamine Plasma Membrane Transport Proteins|*Gene Expression Regulation|Neurons, Dopamine|DNA-Binding Proteins|*Substance Use Disorders|Promoter Regions, Genetic|Cell Nucleus|HIVEP2 protein, human 77 HIVEP2 31406623 J Pediatr Genet 2019 PMC6688883 10.1055/s-0039-1683973 0 0 0 69 Humans|Male|Child|Child, Preschool|Sequencing, Whole Exome|Intellectual Disability|Exome|Developmental Disabilities|Mutation|Exon 77 HIVEP2 31273195 Nat Commun 2019 PMC6609711 10.1038/s41467-019-10809-6 5 0 0 69 Mice|Animals|*Osteoporosis|*Bone|Osteoblast|Bone Formation|*Bone Diseases, Metabolic|Bone Resorption|Osteoclasts|Adeno-Associated Virus|Bone Density|Gene Therapy|RNAi|DNA-Binding Proteins|Disease Models, Animal 77 HIVEP2 31207095 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61271 0 0 0 69 Child|Humans|*Intellectual Disability|*Phenotype|Microcephaly|Developmental Disabilities|Sequencing, Whole Exome|Transcription Factor|Exome|Abnormalities, Multiple|Hypotonia|Mutation, Missense|Nervous System Malformations|HIVEP2 protein, human|DNA-Binding Proteins 77 HIVEP2 30927276 Br J Clin Pharmacol 2019 PMC6595296 10.1111/bcp.13943 2 1 0 69 Child|Humans|Republic of Korea|*Acute Lymphoblastic Leukemia|Mercaptopurine|Pyrophosphatases|Antimetabolites, Antineoplastic|Genotype|Methyltransferases|Polymorphism, Single Nucleotide 77 HIVEP2 30832905 J Am Acad Child Adolesc Psychiatry 2019 10.1016/j.jaac.2018.09.432 0 0 0 69 Humans|Male|Adolescent|*Whole Exome Sequencing|*Autism Spectrum Disorder|Exome|Genetic Predisposition to Disease|*Psychosis|DNA Copy Number Variations|Genomics 77 HIVEP2 30682089 PLoS ONE 2019 PMC6347224 10.1371/journal.pone.0211111 1 0 0 69 Humans|*HIV-1|DICER1 protein, human|*Ribonuclease III|*DEAD-box RNA Helicases|*Virus Replication|MIRN186 microRNA, human|*MicroRNAs|*HIV Infections|Downregulation|mRNA|3' Untranslated Regions|Up-Regulation|Cell Lines 77 HMCN1 31638245 Oncol. Rep. 2019 10.3892/or.2019.7379 0 0 0 37 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cystadenocarcinoma, Serous|Neoplasm Invasiveness|RHOA protein, human|rhoA GTP-Binding Protein|Cancer-Associated Fibroblasts|*Fibroblasts|Cell Movement|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|TYRP1 protein, human|*Membrane Glycoproteins|Biomarkers, Tumor|Cell Proliferation|Upregulation|Survival Rates 47 HMCN1 31635417 Genes (Basel) 2019 PMC6826738 10.3390/genes10100825 0 0 0 37 Humans|*Jews|*Age Related Macular Degeneration|Complement Factor I|Complement Factor H|Gene Frequency|Complement C3|Alleles|Polymorphism, Single Nucleotide|Case-Control Studies|*Judaism 47 HMCN1 31570735 Sci Rep 2019 PMC6769015 10.1038/s41598-019-50171-7 3 1 0 37 Humans|*Stomach Neoplasms|Exome|Paraffin Embedding|*Neoplastic Processes|Mutation|High-Throughput Nucleotide Sequencing|Sequencing, Whole Exome|Formaldehyde|*Biomarkers 47 HMCN1 31447598 Clin Med Insights Oncol 2019 PMC6689917 10.1177/1179554919868482 1 0 0 37 Humans|*Triple Negative Breast Neoplasms|*Mutation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 47 HMCN1 31029013 J Affect Disord 2019 10.1016/j.jad.2019.04.059 2 0 0 37 Humans|Female|Pregnancy|*Depression, Postpartum|Serotonin Plasma Membrane Transport Proteins|*Epigenetic|Catechol O-Methyltransferase|Polymorphism, Genetic|Genotype|Monoamine Oxidase|Mother|Epigenesis, Genetic|*Biomarkers 47 HMCN1 30720096 Mol Med Rep 2019 PMC6423600 10.3892/mmr.2019.9902 3 1 0 37 Humans|Male|DNA Copy Number Variations|*Prostate|*Oncogenes|*Prostatic Neoplasms|Gene Regulatory Networks|Adenocarcinoma|Mutation|Computational Biology|Gene Expression Profiling|Biomarkers, Tumor|Genomics|Neoplasm Grading|Cluster Analysis|Gene Expression Regulation, Neoplastic|Transcriptome|Cell Transformation, Neoplastic 47 HMG20B 31803743 Front Cell Dev Biol 2019 PMC6877547 10.3389/fcell.2019.00289 1 1 0 74 Animals|Swine|*Muscle Development|*RNA, Circular|*Embryonic Development|miRNA|Base Sequence|Muscle, Skeletal 22 HMG20B 30988160 Mol. Cell. Biol. 2019 PMC6580704 10.1128/MCB.00020-19 4 2 0 74 *Lysine|GFI1B protein, human|Repressor Proteins|Proto-Oncogene Proteins|Erythroid Cells|Corepressors|Hematopoiesis|Cell Differentiation|Histone Demethylases|ZMYM2 protein, human|Transcription Factors|DNA-Binding Proteins|Megakaryocytes|HDAC1 protein, human|Histone Deacetylase 1|HDAC2 protein, human|Histone Deacetylase 2|Nerve Tissue Proteins 22 HMX1 31825998 PLoS ONE 2019 PMC6905564 10.1371/journal.pone.0226212 0 0 0 76 Humans|*Genes, Homeobox|Homeodomain Proteins|Transcription Factors|*Myeloid Cells|Gene Expression Regulation, Leukemic|Leukemia, Myeloid, Acute|Cell Differentiation|Hematopoiesis|Lymphopoiesis|Myelodysplastic Syndrome|Myelopoiesis|Hematopoietic Stem Cells|Cell Line, Tumor|Gene Expressions 47 HMX1 31691317 Anim. Genet. 2019 10.1111/age.12876 2 0 0 76 Sheep|Cattle|Animals|Rats|*Genome-Wide Association Study|*Congenital Microtia|*Sheep, Domestic|*Genes, Homeobox|Genotype|Genetic Association Studies|Phenotype|Pedigree|Polymorphism, Single Nucleotide|Homeodomain Proteins|External Ear|Mutation 47 HMX1 31479653 Exp. Eye Res. 2019 PMC6867612 10.1016/j.exer.2019.107787 1 0 0 76 Humans|Mice|Cats|Animals|*Lens, Crystalline|Cataract|*Cell Line|Eye Proteins|Epithelial Cells|Genes, Homeobox|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Gene Expression|*Epithelium|RNA, Messenger|Cells, Cultured|Membrane Proteins|INPPL1 protein, human|Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|Inppl1 protein, mouse 47 HMX1 31469246 Mol Genet Genomic Med 2019 PMC6785430 10.1002/mgg3.959 1 0 0 76 Humans|Goldenhar Syndrome|Phenotype|*Spine|Chromosomal Abnormalities|Abnormalities, Multiple|Ear|Mandible|*Nucleotides 47 HMX1 30967567 Sci Rep 2019 PMC6456618 10.1038/s41598-019-41759-0 3 4 0 76 Saccharomyces cerevisiae|*Levodopa|Mutagenesis, Insertional|Gene Library|DNA Transposable Elements|Base Sequence 47 HMX2 31176356 BMC Genomics 2019 PMC6555990 10.1186/s12864-019-5807-x 1 0 0 20 Animals|*Pinctada|*Transcriptome|*Proteomics|*Oysters|Nacre|Gene Expression Profiling|Animal Shells|*Proteins|China 40 HMX2 31106404 Ann. Hum. Genet. 2019 10.1111/ahg.12327 0 0 0 20 Middle Aged|Humans|Child|*Whole Exome Sequencing|Meniere Disease|Pedigree|Genetic Predisposition to Disease|Exomes|Hearing|*Heredity|*Inheritance|Vestibule, Labyrinth 40 HN1 31878324 Cancers (Basel) 2019 PMC7016611 10.3390/cancers12010061 0 0 0 117 Humans|Mice|Animals|*Oral Cancer|*Carcinoma, Squamous Cell|*Cell Migration|Epithelial-Mesenchymal Transition|Tongue Neoplasms|Cell Proliferation|Cell Line, Tumor|4-Nitroquinoline-1-oxide|Gene Expression Regulation, Neoplastic|Neoplastic Stem Cells|MicroRNAs|*MAP Kinase Signaling System|*Cell Lineage|Arecolin|Apoptosis 129 HN1 31808620 Cancer Med 2019 PMC6997075 10.1002/cam4.2729 1 2 0 117 Humans|Female|*Metformin|Proteomics|*Endometrial Cancers|Carcinoma, Endometrioid|Cell Proliferation|Hypoglycemic Agents|TOR Serine-Threonine Kinases|*Biomarkers|Apoptosis|Cell Line, Tumor|Obesity|*Microtubule 129 HN1 31749294 Kaohsiung J. Med. Sci. 2019 10.1002/kjm2.12156 0 7 0 117 Humans|*Carcinoma, Hepatocellular|*Down-Regulation|*Liver Neoplasms|Neoplasm Recurrence, Local|*Cell Proliferation|MET protein, human|*Proto-Oncogene Proteins c-met|CCND1 protein, human|Cyclin D1|Up-Regulation|Gene Expression Regulation, Neoplastic|Cell Movement|HGF protein, human|Hepatocyte Growth Factor|Signal Transduction|Cell Line, Tumor|Gene Knockdown Techniques|G1 Cell Cycle Arrest 129 HN1 31702540 J. Gen. Virol. 2019 10.1099/jgv.0.001349 0 0 0 117 Animals|*Newcastle disease virus|*Neuraminidase|*Hemagglutinins|HN Protein|Viral Fusion Proteins|Virus Attachment|Virus Internalization|Paramyxovirinae|Amino Acid Substitution 129 HN1 31544381 Zhongguo Zhen Jiu 2019 10.13703/j.0255-2930.2019.09.007 0 0 0 117 *Cerebral Palsy|*Acupuncture Therapy|Acupuncture Points 129 HN1 31532129 Zhen Ci Yan Jiu 2019 10.13702/j.1000-0607.190068 1 1 0 117 Rats|Animals|*Electroacupuncture|*Beclin-1|CASP3 protein, human|*Caspase 3|*Injury, Spinal Cord|*Hindlimb|Spinal Cord|Rats, Sprague-Dawley|Locomotion|*Lower Extremity|Microtubule-Associated Protein 3|LC3 protein, rat 129 HN1 31484559 Trials 2019 PMC6727424 10.1186/s13063-019-3670-3 2 0 0 117 Humans|*Cognitive Impairment, Mild|*Treatment, Acupuncture|Cognitive Function|Electroacupuncture|Aging|Time Factors|Alzheimer Disease 129 HN1 31467572 Evid Based Complement Alternat Med 2019 PMC6699283 10.1155/2019/2735492 0 0 0 117 Rats|Animals|*Parkinson Disease|*Neuroprotective Agents|*Moxibustion|Substantia Nigra|Oxidopamine|Tyrosine Hydroxylase|Dopaminergic Neurons|Dopamine|Tegmental Area, Ventral|Disease Models, Animal 129 HN1 31450798 Molecules 2019 PMC6749330 10.3390/molecules24173070 0 0 0 117 Humans|Animals|Mice|*Head and Neck Squamous Cell Carcinoma|Mice, Nude|Neoplasm Recurrence, Local|Head and Neck Neoplasms|peptide B|Carcinoma, Squamous Cell|Cell Line, Tumor|Peptides|Xenograft|Radiopharmaceuticals|Xenograft Model Antitumor Assays|Optical Imaging|IRDye800|Indoles 129 HN1 31397351 Neural Regen Res 2019 PMC6788231 10.4103/1673-5374.262590 1 0 0 117 Humans|Male|Female|Aged|Middle Aged|*Magnetic Resonance Imaging|*Scalp|Prospective Studies|*Acupuncture|*Acupuncture Therapy|Brain|Acupuncture Points|Rest|Cognition|Healthy Volunteers|*Nervous System Physiological Phenomena|Frontal Lobe|China|Japan 129 HN1 31382998 Trials 2019 PMC6683432 10.1186/s13063-019-3599-6 0 0 0 117 *Electroacupuncture|*Pilot Projects|*Cognitive Impairment, Mild|Acupuncture Therapy|*Computer|Treatment Outcome|Research Design|Time Factors|Alzheimer Disease|Cognition 129 HN1 31376081 Virol Sin 2019 PMC6888793 10.1007/s12250-019-00150-z 0 0 0 117 *Penicillium|Penicillium chrysogenum virus|Mycoviruses|*RNA Viruses|Citrus|Viral Genome|Double-Stranded RNA|Plant Diseases|Open Reading Frames|Viral Proteins|Phylogeny|*Virus Infections|Polyketide Synthases 129 HN1 31368284 Zhen Ci Yan Jiu 2019 10.13702/j.1000-0607.180390 1 0 0 117 Female|Humans|*Acupuncture, Ear|*Sleep Initiation and Maintenance Disorders|Acupuncture Therapy|Acupuncture Points|Sleep|Treatment Outcome|*Perimenopause|*Heart|*Kidney 129 HN1 31257225 Aging (Albany NY) 2019 PMC6660030 10.18632/aging.102060 0 0 0 117 *3' Untranslated Regions|Polyadenylation|Gene Expression Regulation, Neoplastic|Cellular Senescence|Cell Proliferation|Cell Line, Tumor 129 HN1 31146774 Trials 2019 PMC6543690 10.1186/s13063-019-3446-9 0 0 0 117 Humans|Activities of Daily Living|*Cognitive Impairment, Mild|*Acupuncture Therapy|Cognitive Function|Brain|Treatment Outcome|Time Factors|Research Design|*Magnetic Resonance|Republic of Korea 129 HOOK3 31591892 Biochemistry 2019 10.1021/acs.biochem.9b00772 0 2 0 276 *Dynactin Complex|*Cytoplasmic Dyneins|Dynein|Microtubule-Associated Proteins|Microtubules|Kinesin|Biological Transport|Protein Binding|Cytoplasm|Models, Molecular 33 HOOK3 31436348 J. Cell. Biochem. 2019 10.1002/jcb.29316 1 1 0 276 Humans|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Myocytes, Cardiac|*Signal Transduction|MTOR protein, human|*Mammalian Target of Rapamycin|*Apoptosis|PIK3CG protein, human|*Class Ib Phosphatidylinositol 3-Kinase|miRNAs|Cell Hypoxia|Phosphatidylinositol 3-Kinase|CASP3 protein, human|Caspase 3|Upregulation|Myocardial Reperfusion Injury|Bax Protein 33 HOOK3 31320392 J. Cell Biol. 2019 PMC6719453 10.1083/jcb.201812170 3 4 0 276 *Dynein|*Cytoplasmic Dyneins|*Microtubule|Dynactin|Kinesin|Microtubule-Associated Proteins|Biological Transport|*Carrier Proteins|Protein Binding|*Biochemical Phenomena|*Ion Transport 33 HOOK3 31217419 Nat Commun 2019 PMC6584639 10.1038/s41467-019-10644-9 0 5 0 276 Humans|Kinesin|Microtubules|Microtubule-Associated Proteins|*Biological Transport|*Carrier Proteins|Protein Binding|Protein Transport|*Biochemical Phenomena|Neurons|hook3 protein, human|KIF1C protein, human|PTPN21 protein, human|Protein Tyrosine Phosphatases, Non-Receptor 33 HOOK3 30702276 Biochemistry 2019 10.1021/acs.biochem.8b01065 0 2 0 276 Animals|*Dyneins|Dynactin|Microtubule|Microtubule-Associated Proteins|Cytoplasmic Dyneins|*Cell Movement|Biological Transport|Organelles|Protein Domains|*Ion Transport 33 HOOK3 30674580 J. Cell Biol. 2019 PMC6400558 10.1083/jcb.201804183 5 70 0 276 Animals|*Dyneins|*Cytokinesis|Dynactin Complex|Spindle Apparatus|Microtubules|Microtubule-Associated Proteins|Centrosome|Mitosis|Nuclear Envelope|Carrier Proteins|G2 Phase 33 HOOK3 30615611 PLoS Biol. 2019 PMC6336354 10.1371/journal.pbio.3000100 1 0 0 276 Humans|Animals|*Dyneins|Dynactin Complex|Cytoplasmic Dyneins|Microtubule|Microtubule-Associated Proteins|Mitotic Spindle|Carrier Proteins|Protein Transport|Caenorhabditis elegans|Protein Binding|HeLa Cells|hook3 protein, human|RILP protein, human|Adaptor Proteins, Signal Transducing 33 HORMAD1 31444302 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6744910 10.1073/pnas.1902440116 4 0 0 60 Male|Mice|Animals|*Microscopy|Synaptonemal Complex|Meiosis|*Mammalian Chromosome|Spermatocytes|Chromosome Pairing|Prophase I|Cell Cycle Proteins|Chromosome Segregation|Chromosomal Proteins, Non-Histone|Nuclear Proteins|DNA-Binding Proteins|*Mammals|Oocytes|Sycp2 protein, mouse 53 HORMAD1 31237565 Elife 2019 PMC6615865 10.7554/eLife.43966 8 0 0 60 Male|Mice|Animals|*Testis|*Single-Cell Analysis|Spermatogenesis|Sertoli Cells|Spermatocytes|*Gene Expression Regulation|Meiosis|Fertility|Mice, Knockout 53 HORMAD1 30853435 Curr. Biol. 2019 PMC6544150 10.1016/j.cub.2019.02.007 1 5 0 60 Male|Mice|Animals|*DNA Breaks, Double-Stranded|*Spermatocytes|cohesins|*Chromosomal Proteins, Non-Histone|*Cell Cycle Proteins|Homologous Recombination|Meiosis|meiotic recombination protein SPO11|Endodeoxyribonucleases|Chromatin|Histones|Histone-Lysine N-Methyltransferase|Chromosomes|Methylation|DNA|prdm9 protein, mouse 53 HORMAD1 30613165 Cancer Manag Res 2019 PMC6306052 10.2147/CMAR.S187151 7 0 0 60 Humans|*Triple-Negative Breast Cancer|*Transcriptome|*Transcriptome Analyses|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor 53 hotairm1 31880484 Genet Test Mol Biomarkers 2019 10.1089/gtmb.2019.0102 0 0 0 0 60 hotairm1 31876683 Neuroreport 2019 10.1097/WNR.0000000000001380 0 0 0 0 Adult|Humans|HOTAIR long untranslated RNA, human|*RNA, Long Noncoding|*Glioblastoma|MIRN137 microRNA, human|*MicroRNAs|*Cell Proliferation|*Up-Regulation|Downregulation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Brain Neoplasms|Cell Line, Tumor|Cell Movement|*Transcriptional Activation|Apoptosis|*Neoplastic Processes|Disease Progression|Sp1 protein, human 60 hotairm1 31862408 Cancer Lett. 2019 PMC6992348 10.1016/j.canlet.2019.12.022 1 0 0 0 *RNA, Long Noncoding|*Downregulation|*Carcinoma, Renal Cell|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Differentiation|Homeodomain Proteins|Cell Proliferation|Cell Line, Tumor|Leukemia, Myeloid, Acute|Kidney Neoplasms|Hypoxia 60 hotairm1 31853186 Onco Targets Ther 2019 PMC6917485 10.2147/OTT.S222334 0 0 0 0 Humans|Female|*RNA, Long Noncoding|*Cell Proliferation|*Endometrial Cancer|Gene Expression Regulation, Neoplastic|MicroRNAs|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Cell Movement|Upregulation|Apoptosis|Disease Progression 60 hotairm1 31691127 Neurotherapeutics 2019 PMC7283434 10.1007/s13311-019-00799-0 0 2 0 0 Humans|*Glioblastoma|*RNA, Long Noncoding|*Genes, Homeobox|Glioma|Brain Neoplasms|Neoplastic Stem Cells|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Apoptosis|Cell Line, Tumor|Transcription Factors|Upregulation|Tumorigenesis|Neoplasm Grading 60 hotairm1 31512358 J. 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Med. 2019 PMC6815819 10.1111/jcmm.14620 2 2 0 0 *Osteogenesis|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|*RNA, Long Noncoding|*Transcription Factor AP-1|Mesenchymal Stem Cells|Cell Differentiation|*MAP Kinase Signaling System|Gene Expression Regulation|Histone|Osteocytes|Cells, Cultured 60 HOXA6 31165042 Front Oncol 2019 PMC6536611 10.3389/fonc.2019.00394 1 6 0 56 Humans|*Colorectal Cancer|*Promoter Regions, Genetic|DNA Methylation|*Genes, Homeobox|HOXA5 protein, human|*Homeodomain Proteins|CpG Islands|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Colonic Neoplasms|Mutation|*Protein Processing, Post-Translational|Colon|Cohort Studies|HOXA2 protein, human|Hoxa6 protein, human 36 HOXA6 31159758 BMC Cancer 2019 PMC6547586 10.1186/s12885-019-5715-0 0 6 0 56 Humans|Mice|Animals|*RNA, Long Noncoding|Colon Cancer|Tumorigenesis|Gene Expression Regulation, Neoplastic|Cell Proliferation|RNA Interference|HCT116 Cells|*Colon|Cell Movement|Signal Transduction|Mice, Nude|Cell Line, Tumor|*Cell Transformation, Neoplastic|Xenograft Model Antitumor Assays|HOXA5 protein, human|Homeodomain Proteins|Hoxa6 protein, human 36 HOXA6 31114997 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201905_17797 2 3 0 56 Humans|*Carcinoma, Renal Cell|Renal Cancer|MicroRNAs|*Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Down-Regulation|Cell Movement|Apoptosis|Cell Line, Tumor|Carcinogenesis|Hoxa6 protein, human|Homeodomain Proteins|MIRN1294 microRNA, human 36 HOXA6 31081053 Int. 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Oncol. 2019 PMC6521939 10.3892/ijo.2019.4789 1 4 0 56 *Carcinoma, Renal Cell|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Cell Proliferation|*Signal Transduction|*Apoptosis|Kidney Neoplasms|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Upregulation|shRNA|Cell Cycle|mRNA|Phosphorylation 36 HOXB13 31882852 Sci Rep 2019 PMC6934792 10.1038/s41598-019-56657-8 0 0 0 285 Humans|Male|*Prostate|Prostate Cancer|HOXB13 protein, human|*Homeodomain Proteins|Gleason Score|Carcinoma, Acinar Cell|Biomarkers, Tumor|*Carcinoma, Ductal, Breast|Mutation|Breast Neoplasms 273 HOXB13 31878059 Cells 2019 PMC7017003 10.3390/cells9010045 0 0 0 285 Mice|Animals|Humans|*Oncostatin M|*Methylmercury Compounds|HEK293 Cells|*Genes, Homeobox|*Nuclear Protein|HOXB13 protein, human|*Homeodomain Proteins|Oncostatin M Receptor beta Subunit|Interleukin 6|TYRP1 protein, human|Membrane Glycoproteins|Tumor Cells, Cultured|Gene Expression Regulation, Neoplastic|Signal Transduction 273 HOXB13 31866045 Am. J. Hum. Genet. 2019 PMC7042481 10.1016/j.ajhg.2019.11.012 1 0 0 285 *Exome|*Biological Specimen Banks|United Kingdom|Genome-Wide Association Study|Phenotypes|Case-Control Studies|*Phenomic|Models, Genetic|Genetic Variation|Polymorphism, Single Nucleotide|Computer Simulation 273 HOXB8 31827394 Cancer Cell Int. 2019 PMC6889337 10.1186/s12935-019-1036-2 0 15 0 144 *Cell Proliferation|*Pancreatic Cancer|Long Non-Coding RNA|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Neoplasm Invasiveness|Epithelial-Mesenchymal Transition|3' Untranslated Regions|Cell Line, Tumor|*Neoplastic Processes 154 HOXB8 31691359 Mol. Carcinog. 2019 10.1002/mc.23131 0 13 0 144 *mTORC2|enzastaurin|*Proto-Oncogene Proteins c-akt|*Indoles|Protein Kinase Inhibitors|Apoptosis|STAT5A protein, human|STAT5 Transcription Factor|Signal Transduction|Phosphorylation|Cell Proliferation|Receptor, Platelet-Derived Growth Factor alpha|mRNA Cleavage and Polyadenylation Factors|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|LCP1 protein, human|*Microfilament Proteins|Tyrosine Kinase 154 HOXB8 31646435 Neurosci Bull 2019 PMC7142204 10.1007/s12264-019-00436-y 0 0 0 144 Humans|Adult|Phosphatidylinositol 3-Kinases|*Genes, Homeobox|*Sterile Alpha Motif|*Glioma|Glioblastoma|Brain Cancer|*Disease Progression|Epithelial-Mesenchymal Transition|Proto-Oncogene Proteins c-akt|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|SAMD9 protein, human|Cell Proliferation|*Genes, Regulator 154 HOXB8 31644903 Cell Rep 2019 PMC6876991 10.1016/j.celrep.2019.09.045 0 0 0 144 Humans|Female|Animals|Mice|*Microglia|*Compulsive Behavior|*Anxiety|Obsessive-Compulsive Disorder|Grooming|Anxiety Disorders|Disease Models, Animal|Behavior, Animal|Homeodomain Proteins 154 HOXB8 31591481 Oncogene 2019 10.1038/s41388-019-1013-1 0 3 0 144 Humans|*Genes, Homeobox|*Colorectal Cancer|*Oncogenesis|*Oncogenes|*Colonic Neoplasms|Gene Expression Regulation, Neoplastic|Enhancer Elements, Genetic|Transcription Factors|Cell Movement|Prognosis|Basic-Leucine Zipper Transcription Factors|Mutation|BACH1 protein, human|HOXB8 protein, human|Homeodomain Proteins 154 HOXB8 31531882 EMBO J. 2019 PMC6792020 10.15252/embj.2019102161 1 0 0 144 Pancreatic Carcinoma|*Pancreatic Cancer|Hepatocyte Nuclear Factor 3-alpha|Hepatocyte Nuclear Factor 3-beta|*Pancreas|Carcinoma, Pancreatic Ductal|Homeodomain Proteins|Cell Differentiation|Gene Expression Regulation, Developmental|Gene Regulatory Networks 154 HOXB8 31319766 Technol. Cancer Res. Treat. 2019 PMC6640059 10.1177/1533033819861971 1 2 0 144 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Genes, Tumor Suppressor|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Down-Regulation|Apoptosis|HOXB8 protein, human|Homeodomain Proteins 154 HOXB8 31271703 Basic Clin. Pharmacol. Toxicol. 2019 10.1111/bcpt.13288 0 0 0 144 Female|Humans|*RNA, Micro|*Ovarian Cancer|*Genes, Homeobox|*Carcinoma, Ovarian Epithelial|Paclitaxel|Cell Proliferation|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Line, Tumor|Cisplatin|*Ovary|3' Untranslated Regions|Antineoplastic Agents, Phytogenic|Down-Regulation|Genes, Tumor Suppressor|*Neoplastic Processes|Signal Transduction 154 HOXB8 31216372 J. Leukoc. Biol. 2019 10.1002/JLB.2A0818-314R 2 0 0 144 *Neutrophils|*Bone Marrow|*Bone Marrow Cells|*Signal Transduction|Chemotaxis|Homeodomain Proteins|Cell Differentiation|*Oncogene Proteins|Inflammation|Superoxide Anion 154 HOXB8 31204998 Elife 2019 PMC6579556 10.7554/eLife.45957 0 0 0 144 Mice|Humans|Animals|Macrophages|Listeria monocytogenes|Mycobacterium tuberculosis|Mice, Transgenic|Mice, Inbred C57BL 154 HOXB8 31173907 Bone 2019 PMC6708790 10.1016/j.bone.2019.06.002 0 1 0 144 Mice|Animals|*Zebrafish|Osteoclasts|*Bone Remodeling|Bone Resorption|Cell Differentiation|bone resorption factor|Cytokines|Bone Development|Upregulation 154 HOXB8 31097355 Pathol. Res. Pract. 2019 10.1016/j.prp.2019.03.005 0 3 0 144 Humans|Female|*RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|*RNA, Anti-Sense|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|MCF-7 Cells|Cell Line, Tumor|Upregulation|Apoptosis|Disease Progression|HOXB8 protein, human|Homeodomain Proteins|MIF protein, human|Macrophage Migration-Inhibitory Factors|Intramolecular Oxidoreductases 154 HOXB8 31058389 Hum. Mutat. 2019 10.1002/humu.23780 0 0 0 144 Male|Female|Child|Humans|pbx1 protein, human|*Pre-B-Cell Leukemia Transcription Factor 1|*Testis|Gonadal Dysgenesis, 46,XY|Transcription Factors|Homeodomain Proteins|Steroidogenic Factor 1|Sex Determination Processes|Mutation|Sex Differentiation|Nuclear Localization Signal|Amino Acid Sequence 154 HOXB8 30954562 Eur. J. Pharmacol. 2019 10.1016/j.ejphar.2019.04.004 0 6 0 144 Humans|*Osteosarcoma|*Wnt Signaling Pathway|Bone Neoplasms|Cell Movement|Cell Proliferation|*Catenins|beta Catenin|Tumorigenesis|MicroRNAs|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Gene Knockdown Techniques|Cell Transformation, Neoplastic|HOXB8 protein, human|Homeodomain Proteins 154 HoxC10 31812713 Mol. Cell. Probes 2019 10.1016/j.mcp.2019.101491 0 15 0 154 Humans|Sheep|Mice|Animals|*Mesenchymal Stem Cells|Phosphatidylinositol 3-Kinases|Adipogenesis|*Genes, Homeobox|Cell Differentiation|Adipocytes|Osteogenesis|Cell Proliferation|MTOR protein, human|TOR Serine-Threonine Kinases|Signal Transduction|Proto-Oncogene Proteins c-akt|PPAR gamma|Adipose Tissue, White|Upregulation|Lipids|HOXC10 protein, human|Homeodomain Proteins 78 HoxC10 31565488 Cancer Biol Med 2019 PMC6743613 10.20892/j.issn.2095-3941.2018.0277 1 0 0 154 *Glioblastoma|*Prognosis|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Transcriptome|Biomarkers, Tumor 78 HoxC10 31552684 J. Cell. Physiol. 2019 10.1002/jcp.29246 0 9 0 154 *Stomach Neoplasms|*Cytokines|*Cell Migration|*Upregulation|Cell Proliferation|Gene Expression Regulation, Neoplastic|Signal Transduction|Homeodomain Proteins|Cell Line, Tumor|NF-kappa B|*Neoplastic Processes|Promoter Regions, Genetic|Tumor Necrosis Factor-alpha|Transfection 78 HoxC10 31528218 J Cancer 2019 PMC6746115 10.7150/jca.30645 2 2 0 154 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|Epithelial-Mesenchymal Transition|N-Cadherin|Snail Family Transcription Factors|Vimentin|Lymphatic Metastasis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Wnt Signaling Pathway|*Genes, Homeobox|Upregulation|HOXC10 protein, human|Homeodomain Proteins 78 HoxC10 31376087 Clin. Rheumatol. 2019 10.1007/s10067-019-04700-4 1 1 0 154 DNA Methylation|Knee Osteoarthritis|Cartilage, Articular|Chondrocytes|Epigenesis, Genetic|Epigenetics|Cells, Cultured 78 HoxC10 31115563 Oncol. Rep. 2019 PMC6549078 10.3892/or.2019.7164 2 3 0 154 Humans|*Stomach Neoplasms|*Genes, Homeobox|*Cell Proliferation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Movement|Homeodomain Proteins|DNA Methylation|Upregulation|Cell Line, Tumor|Apoptosis|Promoter Regions, Genetic|Xenograft Model Antitumor Assays|HOXC10 protein, human 78 HoxC10 30783203 Br. J. Cancer 2019 PMC6461839 10.1038/s41416-019-0395-8 3 0 0 154 Humans|*Prognosis|Tamoxifen|Estrogen Receptor alpha|MicroRNAs|Antineoplastic Agents, Hormonal|MCF-7 Cells|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Cell Line, Tumor|Apoptosis|Signal Transduction|Biomarkers 78 HoxC10 30673899 Ann. Surg. Oncol. 2019 10.1245/s10434-019-07166-5 2 4 0 154 Humans|*Stomach Neoplasms|*Genes, Homeobox|Neoplasm Recurrence, Local|Gastrectomy|Prognosis|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Lymphatic Metastasis|Cell Movement|Cell Proliferation|Gastric Mucosa|Survival Rate|Stomach|Tumor Cells, Cultured|*Cell Lines|*Phenotype|HOXC10 protein, human 78 hoxc11 31399844 Diabetologia 2019 10.1007/s00125-019-4967-1 1 0 0 92 Animals|*Diabetic Nephropathies|HOTAIR long untranslated RNA, human|*RNA, Long Noncoding|Podocytes|Diabetes Mellitus, Experimental|Diabetes Mellitus, Type 2|Glucose 57 hoxc11 31379707 Front Neurol 2019 PMC6646669 10.3389/fneur.2019.00745 4 0 0 92 57 hoxc11 31181445 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109041 1 0 0 92 Humans|*Nonsmall Cell Lung Cancer|*Down-Regulation|Lung Neoplasms|*Small Cell Lung Carcinoma|*Upregulation|*Transcriptional Activation|A549 Cells|MicroRNAs|Cell Movement|Neoplasm Invasiveness|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Transcription Factors|Apoptosis 57 hoxc11 30988805 Oncol Lett 2019 PMC6447940 10.3892/ol.2019.10137 0 10 0 92 Humans|*Interleukin-15 Receptor|*Prognosis|*DNA Methylation|Kaplan-Meier Analysis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|IL15RA protein, human 57 hoxc11 30808286 BMC Genomics 2019 PMC6390542 10.1186/s12864-019-5530-7 0 3 0 92 Cattle|Animals|*Hamstring Muscles|Myogenesis|*Cell Differentiation|Satellite Cells, Skeletal Muscle|Gene Expression Profiling|*Gene Expression|Cells, Cultured|Breeding|*Paraspinal Muscles 57 hoxc11 30783203 Br. J. Cancer 2019 PMC6461839 10.1038/s41416-019-0395-8 3 0 0 92 Humans|*Prognosis|Tamoxifen|Estrogen Receptor alpha|MicroRNAs|Antineoplastic Agents, Hormonal|MCF-7 Cells|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Cell Line, Tumor|Apoptosis|Signal Transduction|Biomarkers 57 hoxd11 31792005 G3 (Bethesda) 2019 PMC7003097 10.1534/g3.119.400512 0 0 0 136 Animals|Cetacea|Phylogeny|Ruminantia|*Limb 126 hoxd11 31698611 Math Biosci Eng 2019 10.3934/mbe.2019362 0 0 0 136 Child|Humans|*Ganglioneuroblastoma|*Ganglioneuroma|*Exome|*Neuroblastoma|*Whole Exome Sequencing|*Disease Susceptibility 126 hoxd11 31591517 Eur. J. Hum. Genet. 2019 PMC7028936 10.1038/s41431-019-0522-2 1 0 0 136 Humans|In Situ Hybridization, Fluorescence|Genes, Homeobox|Transcription Factors|Homeodomain Proteins|Regulatory Sequences, Nucleic Acid|*Upper Limbs|Gene Expression Regulation, Developmental|Multigene Family|Organogenesis|Translocation, Genetic|Phenotype|Ulna 126 hoxd11 31445923 Dev. Biol. 2019 10.1016/j.ydbio.2019.08.014 0 0 0 136 Animals|homeobox protein HOXA13|Homeodomain Proteins|*Limbs|Animal Fins|Hox Genes|Body Patterning|Gene Expression Regulation, Developmental|Transcription Factors|Zebrafish|Biological Evolution|Xenopus laevis|In Situ Hybridization|Axolotl 126 hoxd11 31221640 Development 2019 PMC6679367 10.1242/dev.167882 2 0 0 136 *Bone|Tendons|Basic Helix-Loop-Helix Transcription Factors|SOX9 Transcription Factor|Ligaments|Gene Expression Regulation, Developmental|Chondrocytes|Stem Cells|Cell Differentiation 126 hoxd11 31209053 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6613147 10.1073/pnas.1904602116 2 0 0 136 Animals|Genes, Homeobox|*Mammals|Homeodomain Proteins|Multigene Family 126 hoxd11 30895612 Dev. Growth Differ. 2019 PMC6850407 10.1111/dgd.12601 2 0 0 136 *Genes, Homeobox|homeobox protein HOXA13|*Homeodomain Proteins|Transcription Factors|Limb|Gene Expression Regulation, Developmental|Body Patterning|*Chondrogenesis|Binding Sites|*Embryonic Development|In Situ Hybridization|DNA Chip|Sequences, Conserved 126 hoxd11 30867848 Dis. Markers 2019 PMC6379867 10.1155/2019/4108474 3 3 0 136 Humans|*DNA Methylation|*Lung Cancer|Cell Free DNA|CpG Islands|Biomarkers, Tumor|DNA, Neoplasm|Neoplasm Staging|Promoter Regions, Genetic|*B-Lymphocytes 126 Hoxd9 31754465 EFORT Open Rev 2019 PMC6836073 10.1302/2058-5241.4.190006 0 0 0 109 Humans|Female|*Hip Dislocation, Congenital|Genetic Predisposition to Disease|Asian|Polymorphism, Single Nucleotide|Acetabulum|Case-Control Studies|CCN6 protein, human|CCN Intercellular Signaling Proteins|HOXB9 protein, human|Homeodomain Proteins|UQCC protein, human|Membrane Proteins 97 Hoxd9 31754347 Cancer Cell Int. 2019 PMC6854692 10.1186/s12935-019-1002-z 0 2 0 109 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Precision Medicine|Nomogram|Prognosis|Neoplasm Recurrence, Local 97 Hoxd9 31746370 Int. J. Oncol. 2019 10.3892/ijo.2019.4915 1 3 0 109 *Thymoma|*Growth Hormone Secretagogue Receptor|*DNA Methylation|*B-DNA|Thymic epithelial tumor|Thymus Neoplasms|CpG Islands|Promoter Regions, Genetic|Neoplasms, Glandular and Epithelial|Tumor Suppressor Proteins|*Epigenetic|Carcinogenesis|Carcinoma|Epigenesis, Genetic 97 Hoxd9 31680311 J. Cell. Biochem. 2019 10.1002/jcb.29467 1 6 0 109 Mice|Animals|*RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|Mice, Nude|*Glioma|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Brain Neoplasms|CDH1 protein, human|N-Cadherin|Cell Line, Tumor|Vimentin|Antigens, CD 97 Hoxd9 31628391 Sci Rep 2019 PMC6800453 10.1038/s41598-019-51457-6 1 0 0 109 Humans|Female|Aged|*DNA Methylation|CpG Islands|Epigenetic|Epigenesis, Genetic|Promoter Regions, Genetic|*Cancer|Gene Expression Regulation, Neoplastic|*Acceleration|PCDH10 protein, human|Cadherins 97 Hoxd9 31591517 Eur. J. Hum. Genet. 2019 PMC7028936 10.1038/s41431-019-0522-2 1 0 0 109 Humans|In Situ Hybridization, Fluorescence|Genes, Homeobox|Transcription Factors|Homeodomain Proteins|Regulatory Sequences, Nucleic Acid|*Upper Limbs|Gene Expression Regulation, Developmental|Multigene Family|Organogenesis|Translocation, Genetic|Phenotype|Ulna 97 Hoxd9 31547840 J. Exp. Clin. Cancer Res. 2019 PMC6755711 10.1186/s13046-019-1399-1 1 3 0 109 Mice|Animals|*Stomach Neoplasms|*Transcriptional Activation|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Prognosis|*Stomach|MicroRNAs|Apoptosis|Mice, Nude|*Neoplastic Processes|Biomarkers, Tumor|Xenograft Model Antitumor Assays|Lymphatic Metastasis|Tumor Cells, Cultured|Signal Transduction|Survival Rate 97 Hoxd9 31504243 Cardiovasc. Res. 2019 PMC7243277 10.1093/cvr/cvz235 0 1 0 109 *Genes, Homeobox|BMP4 protein, human|*Bone Morphogenetic Protein 4|Atherosclerosis|*Inflammation|Stress, Mechanical|Shear Strength|Arteries|Human Umbilical Vein Endothelial Cells|Endothelium, Vascular|Mechanotransduction, Cellular|Cells, Cultured|Regional Blood Flow|Cell Proliferation 97 Hoxd9 31477279 Gynecol. Oncol. 2019 10.1016/j.ygyno.2019.08.026 2 7 0 109 Humans|Female|*Uterine Cervical Neoplasms|*Papillomavirus Infections|*Transcription Factor|*Human Papilloma Virus|*Genes, Homeobox|Human papillomavirus 16|Papillomavirus E7 Proteins|Oncogene Proteins, Viral|*Oncogene|*Promoter Regions, Genetic|Repressor Proteins|RNA, Small Interfering|Cell Line, Tumor|*Phenotype 97 Hoxd9 30992394 Biosci. Rep. 2019 PMC6522733 10.1042/BSR20181989 3 4 0 109 Humans|*Epithelial-Mesenchymal Transition|*Down-Regulation|*Glioma|MicroRNAs|Cell Proliferation|CDH1 protein, human|E Cadherin|Gene Expression Regulation, Neoplastic|Brain Neoplasms|Neoplasm Invasiveness|Cell Movement|Cell Line, Tumor|Antigens, CD|HOXD9 protein, human|Neoplasm Proteins|Homeodomain Proteins|MIRN205 microRNA, human 97 Hoxd9 30979092 Med Sci (Basel) 2019 PMC6524033 10.3390/medsci7040059 1 0 0 109 Hip Dislocation, Congenital|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Genetic Screening|Genetic Linkage|Femur Head 97 Hoxd9 30872674 Sci Rep 2019 PMC6418183 10.1038/s41598-019-40923-w 7 22 0 109 Female|Mice|Animals|*RNA-Seq|Endothelial Cells|Hox Genes|Homeodomain Proteins|Uterus|*B-Lymphocytes|Transcription Factor|Signal Transduction|Cell Differentiation|Cells, Epithelial|Stromal Cells|*Whole Exome Sequencing 97 Hoxd9 30832707 Clin Epigenetics 2019 PMC6399934 10.1186/s13148-019-0634-0 6 15 0 109 *DNA Methylation|*Diagnosis, Differential|*B-DNA|*Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|OPCML protein, human|*GPI-Linked Proteins|*Cell Adhesion Molecules|Biomarkers, Tumor|Bile Duct|*Gallbladder Diseases|*B-Lymphocytes 97 Hrk 31851028 J Bone Joint Surg Am 2019 10.2106/JBJS.19.00756 0 0 0 257 Humans|United States|Medicare|*Patient Selection|*Arthroplasty, Replacement, Knee|Arthroplasty, Replacement, Hip|Centers for Medicare and Medicaid Services, U.S.|Patient Care Bundles|Episode of Care|Reimbursement Mechanisms|Cost Savings 202 Hrk 31848302 mSystems 2019 PMC6918028 10.1128/mSystems.00463-19 0 0 0 257 Humans|Infant|*Dysbiosis|*Gastrointestinal Microbiome|*Bile|RNA, Ribosomal, 16S|*Cholestasis|Bile Acids and Salts|Feces|Liver|*Lipid Metabolism|Bacteria 202 Hrk 31825969 PLoS Comput. Biol. 2019 PMC6927658 10.1371/journal.pcbi.1007485 2 1 0 257 *Breast Cancer 2 Protein|Pro-Apoptotic Proteins|BH3 Interacting Domain Death Agonist Protein|Proto-Oncogene Proteins c-bcl-2|bcl-X Protein|bcl-2 Homologous Antagonist-Killer Protein|bcl-Associated Death Protein|Bcl-2-Like Protein 11|Apoptosis|Proto-Oncogene Proteins|*Mutations|Membrane Proteins|Amino Acid Sequence|Mitochondria|Protein Binding|Binding Site|Protein Interaction Domains and Motifs|*B Cell Lymphoma 202 Hrk 31466290 Cancers (Basel) 2019 PMC6770521 10.3390/cancers11091261 2 0 0 257 Humans|*Carcinoma, Non-Small-Cell Lung|*Mesenchymal Stem Cells|*Prospective Studies|*Lung Neoplasms|*Cancer Stem Cells|TNF-Related Apoptosis-Inducing Ligand|Mesenchymal Stem Cell Transplantation|Prominin 1|Apoptosis|Cell Proliferation|Cell Line, Tumor|Xenograft Model Antitumor Assays|Signal Transduction 202 Hrk 31135059 J. Pathol. 2019 PMC7219509 10.1002/path.5309 1 1 0 257 Humans|Polymyositis|*Myositis|Dermatomyositis|Muscle, Skeletal|Myotubes|HRK protein, human|Muscle Weakness|Gene Expression|Upregulation|Biopsy|Mitochondria|Great Britain|Ireland 202 Hrk 30872780 Leukemia 2019 10.1038/s41375-019-0442-8 3 3 0 257 venetoclax|PTPN6 protein, human|Phosphatidylinositol 3-Kinases|Glycogen Synthase Kinase 3|*Bridged Bicyclo Compounds, Heterocyclic|*Sulfonamides|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|SHP1 Phosphatase|*Lymphoma, Large B-Cell, Diffuse|Myeloid Cell Leukemia Sequence 1 Protein|Antineoplastic Agents|Apoptosis|Xenograft Model Antitumor Assays|Cell Line, Tumor|Cell Proliferation|Drug Synergism|Receptors, Antigen, B-Cell 202 Hrk 30774992 Cell Death Discov 2019 PMC6368544 10.1038/s41420-019-0144-z 2 35 0 257 *Glioblastoma|HRK protein, human|*Apoptosis Regulatory Proteins|BCL2 protein, human|*Proto-Oncogene Proteins c-bcl-2|BCL2L1 protein, human|bcl-XL Protein|*Cell Death|Apoptosis|Brain Neoplasms|TNF-Related Apoptosis-Inducing Ligand|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Nervous System 202 HSPB3 31709619 Mol. Carcinog. 2019 10.1002/mc.23133 0 1 0 1045 Humans|*Heat Shock Protein|Neoplasm Recurrence, Local|*Colorectal Cancer|*Adenocarcinoma|Prognosis|Biomarkers, Tumor|MicroRNAs|Gene Expression Regulation, Neoplastic|Messenger RNA|Quantitative Real Time Polymerase Chain Reaction|Cell Differentiation 48 HSPB6 31882086 Food Res. Int. 2019 10.1016/j.foodres.2019.108739 2 0 0 293 Cattle|Animals|Male|Female|*Proteomics|Meat|Breeding|*Biomarkers|Muscle, Skeletal|HSPB1 protein, human|HSP27 Heat-Shock Proteins|Maine 174 HSPB6 31767683 J. Biol. Chem. 2019 PMC6952609 10.1074/jbc.RA119.011143 1 2 0 293 Humans|*Heat-Shock Proteins, Small|CRYAB protein, human|alpha-Crystallin B Chain|HSPB1 protein, human|HSP27 Heat-Shock Proteins|HSP20 Heat-Shock Proteins|Protein Structure, Quaternary|Protein Multimerization|Protein-Serine-Threonine Kinases 174 HSPB6 31628352 Sci Rep 2019 PMC6802120 10.1038/s41598-019-50941-3 1 2 0 293 Humans|*Phosphoproteins|Scattering, Small Angle|X-Ray Diffraction|Protein Binding|Protein Multimerization|Crystallography, X-Ray|Phosphorylation|14-3-3 Proteins|Models, Molecular 174 HSPB6 31456698 Front Physiol 2019 PMC6700720 10.3389/fphys.2019.01037 0 1 0 293 Rats|Animals|*miRNA|*Lipids|*Aminoglycosides|Epigenesis, Genetic 174 HSPB6 31021818 JCI Insight 2019 PMC6629151 10.1172/jci.insight.122929 2 2 0 293 Humans|Adult|Rats|Mice|Animals|*Ventricular Dysfunction, Right|*Heart Failure|Hypertension, Pulmonary|Hypertrophy, Right Ventricular|Ventricular Remodeling|Myocytes, Cardiac|Cardiac Ventricles|Pulmonary Artery|Disease Models, Animal|Signal Transduction 174 HSPB6 30837897 Front Physiol 2019 PMC6390296 10.3389/fphys.2019.00132 2 9 0 293 *Longevity|*Football|*Soccer|*Autophagy|ATG12 Protein|*Health Promotion|Muscle, Skeletal|Exercise|ATG5 Protein|Signal Transduction|Adaptation, Physiological|Biomarkers 174 HSPB6 30830872 JCI Insight 2019 PMC6478417 10.1172/jci.insight.126464 2 0 0 293 *Heat-Shock Proteins, Small|CRYAB protein, human|alpha-Crystallin B Chain|Apoptosis Regulatory Proteins|Adaptor Proteins, Signal Transducing|Heat-Shock Proteins|Molecular Chaperones|*Heart|Protein Binding|Protein-Serine-Threonine Kinases|Folding, Protein|Mutations 174 HTATSF1 31561539 Animals (Basel) 2019 PMC6826869 10.3390/ani9100727 0 0 0 139 Cattle|Animals|*Alleles|Republic of Korea|Genotypes|Chromosome Mapping|Molecular Sequence Annotation|Polymorphism, Single Nucleotide|Gene Expression Regulation 26 HTATSF1 30847849 Mol. Biol. Rep. 2019 PMC6548758 10.1007/s11033-019-04713-x 0 0 0 139 Humans|Mice|Animals|*Chondrogenesis|*Cell Differentiation|Mesenchymal Stem Cell|Osteogenesis|*Real-Time Polymerase Chain Reaction|Bone Morphogenetic Protein 2|SOX9 protein, human|SOX9 Transcription Factor|Transforming Growth Factor beta|Cells, Cultured|Cell Line|Collagen|AP3D1 protein, human|Adaptor Protein Complex 3|Adaptor Protein Complex delta Subunits|FBXW2 protein, human|F-Box Proteins|ZFP91 protein, human 26 HTATSF1 30699165 PLoS ONE 2019 PMC6353192 10.1371/journal.pone.0211384 1 0 0 139 Humans|Mice|Animals|*Mice, Inbred mdx|*Muscular Dystrophy, Duchenne|*Gene Expression|Muscle, Skeletal|*Disease Models, Animal|*Real-Time Polymerase Chain Reaction|Genes, Regulator|AP3D1 protein, human|Adaptor Protein Complex 3|Adaptor Protein Complex delta Subunits|FBXW2 protein, human|F-Box Proteins|ZFP91 protein, human|Ubiquitin-Protein Ligases|PAK1IP1 protein, human|Intracellular Signaling Peptides and Proteins 26 HTRA3 31811121 Nat Commun 2019 PMC6898346 10.1038/s41467-019-13314-y 0 4 0 62 Humans|*Histones|*Down-Regulation|Cockayne Syndrome|DNA Damage|Poly-ADP-Ribose Binding Proteins|DNA Repair|DNA Repair Enzymes|DNA Helicases|*Senescence, Replicative|Transcription, Genetic|Transcription Factors|Mitochondria|Ultraviolet Rays|Oxidation-Reduction|Mutation|Fibroblasts|HTRA3 protein, human|Serine Endopeptidases 77 HTRA3 31280864 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.07.005 1 0 0 62 Humans|Pregnancy|Female|Molecular Docking Simulation|Serine Endopeptidases|PDZ Domains|Amino Acid Sequence|Protein Conformation|Serine Protease|Protein Binding|High-Temperature Requirement A Serine Peptidase 2|Binding Site|Structure-Activity Relationship|Active Site|HTRA3 protein, human 77 HTRA3 31260151 FEBS J. 2019 10.1111/febs.14977 3 2 0 62 XIAP protein, human|*X-Linked Inhibitor of Apoptosis Protein|*Lung Cancer|Etoposide|Serine Endopeptidases|Apoptosis|Cell Line, Tumor|Isoforms|Cell Death|Cell Proliferation 77 HTRA3 31242033 Arterioscler. Thromb. Vasc. Biol. 2019 PMC6597191 10.1161/ATVBAHA.119.312388 1 4 0 62 Animals|Mice|Endothelial Cells|Wnt Pathway|Axin Protein|beta Catenin|*Catenins|Blood-Brain Barrier|Central Nervous System|*Extracellular Matrix|*Organogenesis 77 HTRA3 31180543 Mol Med Rep 2019 PMC6580024 10.3892/mmr.2019.10292 1 4 0 62 Humans|*RNA, Long Noncoding|*Lung Adenocarcinoma|Lung Neoplasms|Cell Proliferation|Enhancer of Zeste Homolog 2 Protein|Gene Expression Regulation, Neoplastic|Upregulation|Cell Movement|Cell Line, Tumor|Apoptosis|Tumorigenesis|EZH2 protein, human|HTRA3 protein, human|Serine Endopeptidases 77 HTRA3 31013509 Fetal. Diagn. Ther. 2019 10.1159/000497144 1 0 0 62 Pregnancy|Infant, Newborn|Humans|Female|*Pre-Eclampsia|*Gestational Age|*Infant, Small for Gestational Age|Placenta Growth Factor|Pregnancy-Associated Plasma Protein-A|Uterine Artery|*Birth|Pregnancy Proteins|Vascular Endothelial Growth Factor Receptor-1|*Fetal Diseases|Gestational Hypertension|Pregnancy Outcomes|Ultrasonography, Prenatal|Predictive Value of Tests|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1|HTRA3 protein, human|Serine Endopeptidases 77 HTRA3 30940659 Cancer Res. 2019 10.1158/0008-5472.CAN-18-2507 2 5 0 62 *Carcinoma, Non-Small-Cell Lung|*Lung Cancer|Epithelial-Mesenchymal Transition|Prognosis|Adenocarcinoma|Carcinoma, Squamous Cell|Neoplasm Invasiveness|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Lymphatic Metastasis|Apoptosis|*Neoplastic Processes|Tumor Cells, Cultured|Xenograft Model Antitumor Assays 77 HULC 31886187 Biomed Res Int 2019 PMC6899321 10.1155/2019/2601271 0 0 0 0 *RNA, Long Noncoding|*Intrahepatic Cholangiocarcinoma|MicroRNAs|mRNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Computational Biology|Prognosis|Gene Ontology|Biomarkers, Tumor|*Bile Ducts, Intrahepatic|Kaplan-Meier Estimate|*Liver Neoplasms|Bile Duct Neoplasms 165 HULC 31878795 Artif Cells Nanomed Biotechnol 2019 10.1080/21691401.2019.1703730 1 0 0 0 Humans|Animals|*Thyroid Cancer, Papillary|*RNA, Long Noncoding|Phosphatidylinositol 3-Kinases|Thyroid Cancer|miRNAs|Carcinoma, Papillary|Cell Proliferation|Up-Regulation|Gene Expression Regulation, Neoplastic|Cell Movement|Apoptosis|Viability, Cell|Wnt Pathways|Cell Line, Tumor 165 ICA1 31478943 Am. J. Surg. Pathol. 2019 PMC6904430 10.1097/PAS.0000000000001336 0 0 0 128 Adult|Humans|Male|Young Adult|Middle Aged|In Situ Hybridization, Fluorescence|Myofibroma|Angioleiomyoma|Tumors, Glomus|Immunohistochemistry|Hemangiopericytoma|Soft Tissue Neoplasms|Gene Fusions|Myofibromatosis|Myogenesis|Caldesmon|calponin|Microfilament Proteins|Cell Differentiation|PDGFRB|Biomarkers, Tumor|Calcium-Binding Proteins 106 ICA1 30992321 Plant Cell 2019 PMC6588312 10.1105/tpc.18.00938 1 1 0 128 Arabidopsis Proteins|Arabidopsis|*Genes, Duplicate|*Evolution, Molecular|MADS Domain Proteins|Gene Expression Regulation, Plant|Flowers|Alleles|Mutation|*Epistasis, Genetic 106 ICA1 30941163 Front Genet 2019 PMC6434177 10.3389/fgene.2019.00227 1 1 0 128 Male|Pregnancy|Female|Humans|*Pre-Eclampsia|*Epigenome|CpG Islands|DNA Methylation|hydrogen sulfite|Sulfites|Epigenesis, Genetic|Sequence Analysis, DNA|Bioinformatics|Phenotype 106 ICA1 30699097 Pain 2019 PMC6407810 10.1097/j.pain.0000000000001450 0 35 0 128 Rats|Mice|Animals|*Electroacupuncture|*Phosphorylation|*Pain|Hyperalgesia|Freund's Adjuvant|*Autoantigens|Rats, Sprague-Dawley|Spinal Cord|Carrier Proteins|*Islet Cell|Nuclear Proteins|Receptors, AMPA|Mice, Knockout|*Adaptor Proteins, Signal Transducing|*Spine|Inflammation 106 Id4 31847356 Cancers (Basel) 2019 PMC6966672 10.3390/cancers11122021 0 0 0 527 Humans|*Epithelial-Mesenchymal Transition|*DNA Binding Protein|*Lung Adenocarcinoma|Lung Cancer|CDH1 protein, human|E Cadherin|Cell Migration|Snail Family Transcription Factors|Neoplasm Invasiveness|Adenocarcinoma|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Transcription Factors|Signal Transduction|Antigens, CD 382 Id4 31843520 Dev. Biol. 2019 10.1016/j.ydbio.2019.12.006 0 0 0 527 Animals|*Morphogenesis|Cochlea|Cell Differentiation|Inner Hair Cells|Outer Hair Cells|*Mammals|SOX2 protein, human|SOXB1 Transcription Factors|BMP4 protein, human|Bone Morphogenetic Protein 4|Neurogenesis|Signal Transduction|Gene Expression Regulation, Developmental|Epithelium|bHLH Proteins|Cellular Proliferation 382 Id4 31843230 J. Dermatol. Sci. 2019 10.1016/j.jdermsci.2019.11.003 0 0 0 527 Humans|*mRNA|*Psoriasis|*Skin|Gene Expression Profiling|MicroRNAs|Keratinocytes|Microarray Analysis 382 Id4 31819510 Onco Targets Ther 2019 PMC6885564 10.2147/OTT.S229739 1 7 0 527 *Epithelial-Mesenchymal Transition|*Retinoblastoma|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Wnt Signaling Pathway|Cell Proliferation|*Catenins|beta Catenin|Cell Line, Tumor|Apoptosis|Retinal Neoplasms 382 Id4 31801682 Mol. Cell. Endocrinol. 2019 10.1016/j.mce.2019.110670 0 4 0 527 Male|Animals|*Spermatogonia|*Testis|Spermatogenesis|Sertoli Cells|*Transcription Factors|*Genes, Regulator|Sexual Maturation|mRNA|*Gene Expression|Cell Differentiation|Rhesus Monkeys|FN1 protein, human|Fibronectin|Hormone|Proto-Oncogene Proteins c-kit|Endocrine System 382 ifi44 31886294 J Immunol Res 2019 PMC6925913 10.1155/2019/1297131 0 0 0 1206 Humans|*Latent Tuberculosis|*Isoniazid|Interferon-gamma Release Tests|Tuberculin Test|Antitubercular Agents|IL2RA protein, human|*Interleukin-2 Receptor alpha Subunit|USP18 protein, human|*Endopeptidases|*Diagnostic Tests, Routine 128 ifi44 31841994 Mol Ther Nucleic Acids 2019 PMC6920314 10.1016/j.omtn.2019.10.039 1 0 0 1206 Humans|*Carcinoma, Non-Small-Cell Lung|*Gefitinib|*RNA, Long Noncoding|*Lung Neoplasms|Quinazolines|ErbB Receptors|Drug Resistance, Neoplasm|Protein Kinase Inhibitors|Antineoplastic Agents|Cell Line, Tumor|Downregulation|Gene Expression Regulation, Neoplastic|Cell Proliferation|Upregulation 128 ifi44 31798636 Front Genet 2019 PMC6863930 10.3389/fgene.2019.01142 0 0 0 1206 128 ifi44 31755671 Minerva Med. 2019 10.23736/S0026-4806.19.06334-1 0 0 0 1206 Humans|*Bronchoalveolar Lavage|*Immunocompromised Hosts|*Respiratory Tract Infections|Infections, Herpesvirus|Herpesviridae|Bronchoalveolar Lavage Fluid|Simplexvirus|DNA, Viral|Interferon 128 ifi44 31746348 Int. J. Mol. Med. 2019 PMC6889933 10.3892/ijmm.2019.4392 2 2 0 1206 Mice|Animals|*Computational Biology|Gene Ontology|Gene Regulatory Networks|Protein Interaction Maps|Protein Interaction Mapping|Gene Expression Profiling|Databases, Genetic|Transcriptome|*Psoriasis|Gene Expression Regulation, Neoplastic|Signal Transduction|Biomarkers, Tumor|Upregulation|Downregulation|*Calgranulin B|Genes, Regulator|S100A9 protein, mouse 128 ifi44 31703415 Cancers (Basel) 2019 PMC6896100 10.3390/cancers11111749 2 1 0 1206 Humans|Pancreatic Carcinoma|*Pancreatic Neoplasms|*Adenocarcinoma|*Transcriptome|*Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate|DNA Methylation|Survival Rate|LRIG1 protein, human|Membrane Glycoproteins 128 ifi44 31455651 mBio 2019 PMC6712396 10.1128/mBio.01839-19 3 34 0 1206 *Virus Replication|IRF3 protein, human|Interferon Regulatory Factor 3|tacrolimus binding protein 5|*Tacrolimus Binding Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Interferon|Innate Immune Responses|Signal Transduction|I-kappa B Kinase|Phosphorylation|Nuclear Factor-Kappab|Antiviral Agents|Infections, Viral|Virus 128 ifi44 31440254 Front Immunol 2019 PMC6693476 10.3389/fimmu.2019.01880 2 0 0 1206 Humans|*Mixed Connective Tissue Disease|*Epigenome|Lupus Erythematosus, Systemic|Autoantibodies|Sclerosis, Systemic|Rheumatoid Arthritis|Ribonucleoprotein, U1 Small Nuclear|Ribonucleoprotein 128 ifi44 31104071 J Crohns Colitis 2019 PMC6821155 10.1093/ecco-jcc/jjz079 0 0 0 1206 Humans|Chromosome 9, tetrasomy 9p|*Aneuploidy|*Mosaicism|*Chromosomes, Human, Pair 9|Chromosome Disorders|Tetrasomy|*Inflammatory Bowel Disease 128 ifi44 30967136 BMC Med. Genet. 2019 PMC6454587 10.1186/s12881-019-0770-6 1 2 0 1206 Paraganglioma|*Paraganglioma, Extra-Adrenal|Carotid Body Tumor|*Head and Neck Neoplasms|Mutation|Genetic Predisposition to Disease|Neoplastic Syndromes, Hereditary 128 ifi44 30867315 J. Virol. 2019 PMC6532090 10.1128/JVI.02123-18 0 0 0 1206 Humans|Mice|Animals|*HIV-1|*Kinetics|*HIV Infections|IRF3 protein, human|Interferon Regulatory Factor 3|SAM Domain and HD Domain-Containing Protein 1|Type I Interferon|Macrophages|TBK1 protein, human|Protein-Serine-Threonine Kinases|Immunity, Innate|NF-kappa B|Dendritic Cells|Virus Replication|Signal Transduction 128 ifi44 30846988 Front Immunol 2019 PMC6393381 10.3389/fimmu.2019.00281 3 21 0 1206 Humans|Female|TLR7 protein, human|*Toll-Like Receptor 7|*Phosphorylation|Leukocytes, Mononuclear|*B-Lymphocytes|*Signal Transduction|Sjogren's Syndrome|STAT1 Transcription Factor|Interferon Type I 128 ifi44 30666255 Front Immunol 2019 PMC6330328 10.3389/fimmu.2018.03085 1 0 0 1206 128 IFI44L 31886294 J Immunol Res 2019 PMC6925913 10.1155/2019/1297131 0 0 0 68 Humans|*Latent Tuberculosis|*Isoniazid|Interferon-gamma Release Tests|Tuberculin Test|Antitubercular Agents|IL2RA protein, human|*Interleukin-2 Receptor alpha Subunit|USP18 protein, human|*Endopeptidases|*Diagnostic Tests, Routine 94 IFI44L 31865146 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109717 1 0 0 68 Female|Humans|CADM1 protein, human|*Cell Adhesion Molecule-1|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Ovarian Cancer|*Carcinoma, Ovarian Epithelial|MTOR protein, human|*TOR Serine-Threonine Kinases|*Cell Proliferation|Signal Transduction|Cell Movement|Cell Line, Tumor|Apoptosis|C4BPA protein, human|Complement C4b-Binding Protein 94 IFI44L 31850088 J Res Med Sci 2019 PMC6906918 10.4103/jrms.JRMS_83_19 0 0 0 68 Humans|*Leukocytes, Mononuclear|*Lupus Erythematosus, Systemic|DNA Methylation|Promoter Regions, Genetic|Epigenesis, Genetic|TYRP1 protein, human|*Membrane Glycoproteins|Genome-Wide Association Study|*Leukocytes|Case-Control Studies|Interferons 94 IFI44L 31803541 PeerJ 2019 PMC6886488 10.7717/peerj.8162 0 1 0 68 Humans|*Computational Biology|Gene Ontology|Module, Gene|Protein Interaction Maps|Gene Expression Profiling|Gene Expression Profiles|Databases, Genetic|Protein Interaction Mapping|Software|Gene Expression Regulation, Neoplastic|Prognosis|*Myelodysplastic Syndrome|Signal Transduction|Biomarkers 94 IFI44L 31798636 Front Genet 2019 PMC6863930 10.3389/fgene.2019.01142 0 0 0 68 94 IFI44L 31542790 Med. Sci. Monit. 2019 PMC6774267 10.12659/MSM.917097 1 0 0 68 Humans|*Laryngeal Neoplasms|*Apoptosis|interferon-alpha 8|*Interferon-alpha|IFNA13 protein, human|Endoplasmic Reticulum Stress|Signal Transduction|Cell Proliferation|Cell Line, Tumor 94 IFI44L 31440254 Front Immunol 2019 PMC6693476 10.3389/fimmu.2019.01880 2 0 0 68 Humans|*Mixed Connective Tissue Disease|*Epigenome|Lupus Erythematosus, Systemic|Autoantibodies|Sclerosis, Systemic|Rheumatoid Arthritis|Ribonucleoprotein, U1 Small Nuclear|Ribonucleoprotein 94 IFI44L 31435814 Mol. Cell. Biochem. 2019 10.1007/s11010-019-03611-x 0 0 0 68 Humans|Human Umbilical Vein Endothelial Cells|Cell Movement|Cell Proliferation|Neovascularization, Physiologic|MicroRNAs|Upregulation|matrigel|Laminin|Collagen|Proteoglycans|Drug Combinations 94 IFI44L 31434731 J. Virol. 2019 PMC6803278 10.1128/JVI.01159-19 1 11 0 68 IRF3 protein, human|Interferon Regulatory Factor 3|*Antiviral Agents|Interferon|Phosphorylation|I-kappa B Kinase|Innate Immune Responses|Nuclear Factor-Kappab|Interferon Regulatory Factor-7|Signal Transduction|I-kappa B Proteins|Virus Replication|tacrolimus binding protein 5|Tacrolimus Binding Proteins|Virus Infections|Double-Stranded RNA 94 IFI44L 31416482 BMC Res Notes 2019 PMC6694656 10.1186/s13104-019-4562-z 1 0 0 68 *RNA|*Type I Interferon|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Blood Specimen Collection|Blood Preservation|*Complement Factor B|*Diagnostic Tests, Routine 94 IFI44L 31409879 Sci Rep 2019 PMC6692396 10.1038/s41598-019-48162-9 2 0 0 68 Child|Humans|*Bacterial Infections|*Fever|Virus Diseases|*Real-Time Polymerase Chain Reaction|Biomarkers|Transcriptomes|Gene Expression Profiling|Diagnosis, Differential|*Biological Assay 94 IFIT5 31658992 RNA 2019 PMC6913129 10.1261/rna.073304.119 0 1 0 80 *mRNA|*Kinetics|RNA Caps|Protein Biosynthesis|Carrier Proteins|Protein Binding|RNA, Viral|Neoplasm Proteins|Models, Molecular 65 IFIT5 31494269 Genomics Proteomics Bioinformatics 2019 PMC6818352 10.1016/j.gpb.2018.11.004 0 0 0 80 Humans|*Autoantibodies|*Lupus Erythematosus, Systemic|Antibodies, Antinuclear|Lupus Nephritis|Immunoglobulin M|Immunoglobulin G|Lupus Erythematosus, Discoid|ELISA|HMGB1|Western Blot|Case-Control Studies|SRP19 protein, human|Signal Recognition Particle|*Cell Death|DNA Repair|VRK1 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins 65 IFIT5 31333643 Front Immunol 2019 PMC6624447 10.3389/fimmu.2019.01463 1 0 0 80 Animals|*Peste-des-petits-ruminants virus|*Transcriptome|*Goats|*Monocytes|Leukocytes, Mononuclear|Peste-des-Petits-Ruminants|Goat Diseases|*Lymphocytes|Transcriptome Analysis|Interferon|Antibodies, Viral|Antiviral Agents 65 IFIT5 31324030 Vaccines (Basel) 2019 PMC6789484 10.3390/vaccines7030063 0 1 0 80 Animals|*Oncorhynchus mykiss|*Transcriptome|*Proteomics|Novirhabdovirus|Hemorrhagic Septicemia, Viral|*Erythrocyte Count|*Red Blood Cells|Fish Diseases|Antigen Processing|Cell Line|Type I Interferon 65 IFIT5 31164632 Cell Death Dis 2019 PMC6547745 10.1038/s41419-019-1669-z 2 1 0 80 Humans|*Epithelial-Mesenchymal Transition|*Urinary Bladder Neoplasms|Cell Migration|MicroRNAs|Gene Expression Regulation, Neoplastic|*Disease Progression|Downregulation|Cell Line, Tumor|Cell Proliferation|Prognosis|Signal Transduction|IFIT5 protein, human|Neoplasm Proteins 65 IFIT5 31040842 Front Immunol 2019 PMC6476978 10.3389/fimmu.2019.00613 2 0 0 80 Animals|*Oncorhynchus mykiss|Proteomics|Novirhabdovirus|Hemorrhagic Septicemia, Viral|*Erythrocyte Count|*Red Blood Cells|*Antiviral Agents|Type I Interferon|Erythroblasts|Immunologic Factors|Immunoglobulins|Cell Line 65 IFIT5 30999161 Res. Vet. Sci. 2019 10.1016/j.rvsc.2019.04.003 1 0 0 80 Animals|*Hepatitis Virus, Duck|*Ducks|Phylogeny|Leukocytes, Mononuclear|Hepatitis, Viral, Animal|Picornaviridae Infections|Poultry Diseases|Chicken|*Cloning, Molecular|Innate Immune Responses|Liver|Poly I-C|Amino Acid Sequence|RNA, Messenger 65 IFIT5 30906803 Am J Clin Exp Urol 2019 PMC6420704 3 4 0 80 Humans|*Renal Cancer|*Epithelial-Mesenchymal Transition|Renal Cell Carcinoma|RNA, Micro|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|Cell Line, Tumor|RNA, Small Interfering|Cell Movement|STAT1 protein, human|STAT1 Transcription Factor|*Neoplastic Processes|Interferon|IFIT5 protein, human|Neoplasm Proteins 65 IFIT5 30877097 Cancer Res. 2019 10.1158/0008-5472.CAN-19-0083 1 1 0 80 Humans|Male|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|MicroRNAs|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Prostatic Neoplasms|Neoplasm Proteins|Cell Line, Tumor|Cell Movement 65 IFIT5 30772492 Autoimmun Rev 2019 10.1016/j.autrev.2018.11.004 0 0 0 80 Humans|Female|Pregnancy|*Antiphospholipid Syndrome|*Pre-Eclampsia|Leukocytes, Mononuclear|Lupus Erythematosus, Systemic|Autoantibodies|Interferon Type I 65 IFITM5 31792954 Immunology 2019 PMC7078001 10.1111/imm.13163 1 0 0 60 *Interferon|leu-13 antigen|Antigens, Differentiation|*Membrane Proteins|Virus Internalization|*Antiviral Agents|*Adaptive Immunity|Endosomes|Cell Line, Tumor 82 IFITM5 31715670 Zhonghua Yi Xue Za Zhi 2019 10.3760/cma.j.issn.0376-2491.2019.42.011 0 0 0 60 82 IFITM5 31472299 Bone 2019 PMC6945817 10.1016/j.bone.2019.115047 0 1 0 60 Child|Humans|Female|Bruck syndrome 1|Bruck syndrome 2|*Osteogenesis Imperfecta|*Arthrogryposis|*Musculoskeletal Abnormalities|Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase|*Contracture|Genes, Recessive|Phenotype|Type I Collagen|Mutation|Bone Density|Fractures, Bone|*Joint Dislocations|Bone Formation|Hydroxylation|Codon, Nonsense|Mutation, Missense 82 IFITM5 31429852 Genet. Mol. Biol. 2019 PMC6726155 10.1590/1678-4685-GMB-2018-0043 0 0 0 60 Humans|*Osteogenesis Imperfecta|Genes, Recessive|Mutation|Collagen Type I|Genotype|Brazil|FKBP10 protein, human|Tacrolimus Binding Proteins 82 IFITM5 31398796 Int J Mol Sci 2019 PMC6719045 10.3390/ijms20163859 1 1 0 60 Humans|*Fluorescence Resonance Energy Transfer|*Flow Cytometry|leu-13 antigen|Antigens, Differentiation|Virus Entry|Protein Transport|Endosomes|HEK293 Cells|RNA-Binding Proteins|Co-Immunoprecipitations|Membrane Proteins|Antiviral Agents|Cell Line, Tumor|IFITM3 protein, human 82 IFITM5 31363794 Osteoporos Int 2019 PMC7083816 10.1007/s00198-019-05076-6 0 0 0 60 Humans|*Osteogenesis Imperfecta|Japan|*Genotype-Phenotype Correlations|*Sequencing, Next-Generation|*Genetic Testing|DNA Mutational Analysis|Mutation|Collagen Type I|Phenotype|Genotype 82 IFITM5 31273469 Arch. Virol. 2019 10.1007/s00705-019-04340-8 0 0 0 60 Animals|*Orthoreovirus, Avian|*Chickens|*Transcriptome|*Signal Transduction|Poultry Diseases|Immunity, Innate|Orthoreovirus|Interferon-Induced Helicase, IFIH1|Cytokines|Virus Replication|Host-Pathogen Interactions|*Immune System Phenomena|*Lymphocytes 82 IFITM5 31244780 Front Endocrinol (Lausanne) 2019 PMC6581704 10.3389/fendo.2019.00375 1 0 0 60 Humans|Osteogenesis Imperfecta, Type V|*Osteogenesis Imperfecta|Mutation|Phenotype|5' Untranslated Regions|Membrane Proteins|Bone and Bones 82 IFITM5 31159867 Hum. Genomics 2019 PMC6547447 10.1186/s40246-019-0209-3 1 1 0 60 Humans|Osteogenesis Imperfecta, Type V|Osteogenesis Imperfecta, Type IV|*Osteogenesis Imperfecta|Vietnam|5' UTR|Point Mutation|Ossification|Membrane Proteins|Phenotype|IFITM5 protein, human 82 IFITM5 31099171 Mol Genet Genomic Med 2019 PMC6625150 10.1002/mgg3.723 1 0 0 60 Osteogenesis Imperfecta, Type V|*Osteogenesis Imperfecta|Phenotype|Mutation|Membrane Proteins|Bone and Bones|*Muscle|*Heterotopic Ossification 82 IFITM5 30985308 Clin. Dysmorphol. 2019 10.1097/MCD.0000000000000279 1 0 0 60 Child|Humans|Female|Osteogenesis imperfecta, type 6|Osteogenesis Imperfecta, Type V|*Osteogenesis Imperfecta|Sexual Maturation|Phenotype|Heterozygote|Mutation|Membrane Proteins|Fractures, Bone|Mutation, Missense|Bone|IFITM5 protein, human 82 IFRD1 31516920 Data Brief 2019 PMC6727176 10.1016/j.dib.2019.104142 0 0 0 110 Humans|Animals|Mice|*Sea Bream|*Interferon|Iridoviridae|Edwardsiella tarda|Streptococcus iniae|DNA Virus Infections|Iridovirus|Fish Diseases|Fish Proteins|Immunity, Innate|Enterobacteriaceae Infections|Streptococcal Infections|Gene Expression Regulation|*Antiviral Agents|Gene Expression Profiling|Cloning, Molecular|Amino Acid Sequence|Phylogeny 74 IFRD1 31138312 J Transl Med 2019 PMC6540543 10.1186/s12967-019-1930-3 2 0 0 110 *Glioblastoma|*Prognosis|Glioma|Brain Neoplasms|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Regulatory Networks|Transcriptome|RNA, Messenger 74 IFRD1 31118040 J Transl Med 2019 PMC6530130 10.1186/s12967-019-1909-0 3 0 0 110 Humans|*Amyotrophic Lateral Sclerosis|*Biomarkers|Gene Expression Profiling|*Hypoxia|*Leukocyte Disorders 74 IFRD1 31017046 Stem Cells Dev. 2019 PMC6661922 10.1089/scd.2019.0027 0 0 0 110 *Periodontitis|*Osteoclastogenesis|Alveolar Bone Loss|Porphyromonas gingivalis|Interleukin-6|Lipopolysaccharides|Inflammation Mediators|RNA, Micro 74 IFRD1 30606922 Yakugaku Zasshi 2019 10.1248/yakushi.18-00154-1 0 1 0 110 RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteoblasts|Osteoclasts|Osteoclastogenesis|*Gene Expression Regulation|Sp7 Transcription Factor|TNFRSF11B protein, human|Osteoprotegerin|Cell Differentiation|Resorptions, Bone|RANK Ligand|Bone|Transcription Factors|Signal Transduction|Cells, Cultured 74 IGIP 30877705 Diabetes Metab J 2019 PMC6712231 10.4093/dmj.2018.0105 0 1 0 16 Humans|*Incretins|*Diabetes Mellitus, Type 2|Gastric Inhibitory Polypeptide|Glucagon-Like Peptide 1|Blood Glucose|C-Peptide|Insulin|Glucagon|Insulin Secretion|3'-(1-butylphosphoryl)adenosine 29 IGIP 30622762 Curr Health Sci J 2019 PMC6295178 10.12865/CHSJ.44.01.15 0 0 0 16 Pregnancy|Female|Humans|Adult|*Fetal Blood|*Placenta|Pre-Eclampsia|Fetal Growth Retardation|*Prenatal Care|Gestational Age|*Fetus|Thrombophilia|*Hemodynamics|Fetal Death|Pregnant Woman|Maternal Mortality|*Survey 29 IGLL5 31806993 Onco Targets Ther 2019 PMC6839572 10.2147/OTT.S227122 0 0 0 24 Humans|Male|Middle Aged|*Lymphoma, Large B-Cell, Diffuse|*Genomics|Prognosis|Mutations|Myeloid Differentiation Factor 88|Oligonucleotide Array Sequence Analysis|Genes, myc|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Biomarkers, Tumor 21 IGLL5 31558468 Blood 2019 PMC6871305 10.1182/blood.2019001880 3 4 0 24 Humans|*Burkitt Lymphoma|Epstein Barr Virus Infection|Herpesvirus 4, Human|Mutation|Mutation Frequency|Phenotypes|Genomics|BCL7A protein, human|Microfilament Proteins|Oncogene Proteins 21 IGLL5 31522287 Virchows Arch. 2019 10.1007/s00428-019-02658-x 0 0 0 24 Humans|Adolescent|*Immunity, Innate|*Lymphoid Cells|Neoplasm Recurrence, Local|*Helper Cell|*Lymphoma|GATA3 protein, human|GATA3 Transcription Factor|B-Lymphocytes|Cell Differentiation|Flow Cytometry|Cells, Cultured|Gene Expression Regulation|Inflammation|*Phenotype|Tumor Microenvironment 21 IGLL5 30653263 J. Periodontol. 2019 10.1002/JPER.18-0477 1 0 0 24 *Chronic Periodontitis|*Proteomics|*Gingiva|*Genomics|Tandem Mass Spectrometry|Transcriptomes 21 IGLL5 30606723 Blood Adv 2019 PMC6325301 10.1182/bloodadvances.2018026419 3 0 0 24 Humans|*Databases, Genetic|*Mutations|*B Cell Lymphoma|Promoter Regions, Genetic|Genome, Human|Sequencing, Whole Genome|Computational Biology|Gene Expression Regulation, Neoplastic|Polymorphism, Single Nucleotide|Cell Transformation, Neoplastic|Oncogenesis 21 IGSF11 31484064 Cell Rep 2019 10.1016/j.celrep.2019.07.073 3 1 0 18 Humans|*Immunoglobulin V|*Lymphocyte Activation|CTLA4 protein, human|CTLA-4 Antigen|T-Lymphocytes|B7 Antigens|Programmed Cell Death 1 Receptor|Immunotherapy|Cancer|*Epitopes 27 IGSF3 31560140 Cell Prolif. 2019 PMC6869366 10.1111/cpr.12693 1 2 0 44 Humans|*Osteopetrosis|*Osteogenesis|Osteoclast|Bone Resorption|RANK Ligand|Cell Differentiation|NFATC Transcription Factors|Osteoblasts|Tartrate-Resistant Acid Phosphatase|Signal Transduction 20 IGSF3 31397435 Mol. Biol. (Mosk.) 2019 10.1134/S0026898419040141 0 0 0 44 Paraganglioma|*Head and Neck Neoplasms|Succinate Dehydrogenase|Sequencing, Whole Exome|*Paraganglioma, Extra-Adrenal|Mutation|Genetic Predisposition to Disease 20 IGSF3 30968251 Hum. Genet. 2019 PMC6554238 10.1007/s00439-019-02008-6 0 1 0 44 Humans|*Whole Exome Sequencing|*Asian Continental Ancestry Group|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genome-Wide Association Study|Genetic Loci|Genotype|Phenotypes|Mutations|Skull|Transcription Factors|USP40 protein, human|Ubiquitin Thiolesterase 20 IGSF3 30885246 Stem Cell Res Ther 2019 PMC6423778 10.1186/s13287-019-1209-x 8 3 0 44 Humans|Aged|*Induced Pluripotent Stem Cells|*Rejuvenation|Mesenchymal Stem Cells|Cell Differentiation|Cell Proliferation 20 ILDR1 31861965 J. Dent. Res. 2019 10.1177/0022034519896749 0 0 0 64 Humans|Mice|Rats|Animals|*MARVEL Domain Containing 2 Protein|*Gland, Salivary|Tight Junctions|Occludin|Submandibular Gland|Salivation|Claudin-4|Cell Membrane Permeability|Epithelium|Saliva|Epithelial Cells|fluorescein isothiocyanate dextran|Fluorescein-5-isothiocyanate|Cell Line|Permeability|Dextran 40|ILDR1 protein, human|Receptors, Cell Surface 35 ILDR1 31645637 Sci Rep 2019 PMC6811684 10.1038/s41598-019-51630-x 0 0 0 64 *Genome-Wide Association Study|*Presbycusis|SNPs|Hearing|Phenotype|Genetic Predisposition to Disease|Genotype|Deafness|Hair Cells, Auditory 35 ILDR1 31600786 Hum. Mol. Genet. 2019 PMC7001601 10.1093/hmg/ddz228 1 1 0 64 Humans|Genome-Wide Association Study|Genetic Susceptibility|Single Nucleotide Polymorphisms|Linkage Disequilibrium|*Lymphoma, Large B-Cell, Diffuse|Allele Frequency|Genotype|Odds Ratio|*Chromosome Structures|ILDR1 protein, human|Receptors, Cell Surface 35 ILDR1 31139206 Front Genet 2019 PMC6527781 10.3389/fgene.2019.00412 1 0 0 64 Cattle|Female|Animals|*Genome-Wide Association Study|Dairying|Lactation|Milk|Quantitative Trait, Heritable|Phenotypes|Fertility|Genome|Genotype|Polymorphism, Single Nucleotide|Genomics 35 ILDR1 30804975 Front Genet 2019 PMC6370629 10.3389/fgene.2019.00001 1 3 0 64 Male|Humans|Adult|*High-Throughput Nucleotide Sequencing|Hearing Loss, Sensorineural|*Homozygote|Hearing Impairment|Pedigree|Deafness|Chinese|Genetic Predisposition to Disease|Mutation|Ear, Inner|Amino Acid Sequence|Genotype 35 immp2l 31233820 Behav. Brain Res. 2019 10.1016/j.bbr.2019.112057 2 0 0 32 Male|Female|Animals|Mice|*Tourette Syndrome|*Autism Spectrum Disorder|Exons|Genetic Predisposition to Disease|Disorder, Neurodevelopmental|*Behavior Rating Scale|Endopeptidases 57 immp2l 30675382 NPJ Genom Med 2019 PMC6341098 10.1038/s41525-018-0075-2 8 0 0 32 Humans|*Autistic Disorder|Exons|Exome|DNA Copy Number Variations|Nerve Tissue Proteins|Genetic Predisposition to Disease|Mutation|Faeroe Islands 57 immp2l 30623622 Ann Lab Med 2019 PMC6340852 10.3343/alm.2019.39.3.299 4 0 0 32 Child|Humans|*Intellectual Disability|*Autism Spectrum Disorder|*Prospective Studies|Republic of Korea|*Diagnostic Tests, Routine|*Abnormalities, Multiple|Developmental Disabilities|Karyotyping|Chromosome Aberrations|*Chromosomes B|DNA Copy Number Variations|Chromosomes|Oligonucleotide Array Sequence Analysis|Genetic Testing 57 IMPG1 31785455 Int. J. Pediatr. Otorhinolaryngol. 2019 10.1016/j.ijporl.2019.109689 0 0 0 26 Humans|*DNA Copy Number Variations|Hearing Loss, Sensorineural|Myosin Heavy Chains|Pedigree|Deafness|Mutation 29 IMPG1 30688845 Retin Cases Brief Rep 2019 10.1097/ICB.0000000000000843 0 0 0 26 Adult|Humans|*Vitelliform Macular Dystrophy|Fluorescein Angiography|*Mutation|Retina|Electroretinography|Tomography, Optical Coherence|Retinal Pigment Epithelium|Eye Proteins|Visual Acuity|Proteoglycans 29 INF2 31871199 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6955303 10.1073/pnas.1914072117 0 0 0 268 acetylated actin|*Actins|*Lysine|*Acetylation|*Polymerization|Microfilament Proteins|Actin Cytoskeleton|Formins|Glomerulosclerosis, Focal Segmental|Protein Binding|Protein Domain|Mutation 260 INF2 31820591 Cytoskeleton (Hoboken) 2019 10.1002/cm.21588 0 3 0 268 Humans|*Tropomyosin|*Stress Fibers|*Formins|Microfilaments|Actin|*Osteosarcoma|Isoforms|Cytoskeletal Proteins|Polymerization|Protein Binding|DAAM1 protein, human|Adaptor Proteins, Signal Transducing 260 INF2 31754104 Nat Commun 2019 PMC6872576 10.1038/s41467-019-13322-y 1 2 0 268 *Actins|*Chromatin|*Cell Nuclei|Actin Cytoskeleton|Microfilament Proteins|Endoplasmic Reticulum|*Calcium, Dietary|Formins 260 INF2 31515790 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.09.016 0 0 0 268 *Charcot-Marie-Tooth Disease|*Pedigree|Glomerulosclerosis, Focal Segmental|*Kidney Diseases|*Hereditary Sensory and Motor Neuropathy|Microfilament Proteins|Mutations|Formins|*Urinary Tract 260 INF2 31413070 J. Cell. Sci. 2019 PMC6765187 10.1242/jcs.234435 3 3 0 268 *Actin Filament|Mitochondrial Dynamics|*Mitochondria|Actin|Inner Mitochondrial Membrane|GTP Phosphohydrolases|Dynamins|Mitochondrial Proteins|Mitophagy|Microtubule-Associated Proteins|Microfilament Proteins|Arp2-3 Complex|Cytosol|Protein Multimerization|Formins 260 INF2 31354004 J. Recept. Signal Transduct. Res. 2019 10.1080/10799893.2019.1638402 0 0 0 268 260 INF2 31308032 Ann. Clin. Lab. Sci. 2019 1 0 0 268 Child|Humans|*Nephrotic Syndrome|DNA Mutational Analysis|Mutation|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Genetic Predisposition to Disease|WT1 Proteins|Genotype|Chinese|China 260 INF2 31215743 Cytoskeleton (Hoboken) 2019 10.1002/cm.21547 0 0 0 268 Animals|Female|Caenorhabditis elegans|*Formins|Caenorhabditis elegans Proteins|Intercellular Junctions|Cell Polarity|Cells, Epithelial|Epithelium|Oocyte|Ovulation 260 INF2 31144478 Mol Genet Genomic Med 2019 PMC6625365 10.1002/mgg3.741 1 0 0 268 Humans|*Nephritis, Hereditary|*Prognosis|Collagen Type IV|*Genotype-Phenotype Correlation|*Chinese|Pedigree|Mutations|Autoantigens 260 INF2 31112687 Curr. Biol. 2019 10.1016/j.cub.2019.03.061 0 2 0 268 acetylated actin|*Actins|*Formins|Microfilament Proteins|Actin Cytoskeleton|*Post-Translational Modifications|Carrier Proteins|Glomerulosclerosis, Focal Segmental|Lysine 260 INF2 31096240 Nephron 2019 PMC6727320 10.1159/000499937 2 0 0 268 Adult|Humans|*Glomerulosclerosis, Focal Segmental|Kidney|Podocyte|Kidney Glomerulus|Genetic Testing|Microfilament Proteins|Mutation 260 INF2 30962575 Nat. Cell Biol. 2019 PMC6501848 10.1038/s41556-019-0307-4 8 4 0 268 Mice|Animals|acetylated actin|*Actins|*Formins|*Lysine|Microfilament Proteins|Charcot Marie Tooth Disease|Focal Segmental Glomerulosclerosis|Mutations|Mutations, Missense|INF2 protein, mouse 260 INF2 30893012 Mol. Biol. Cell 2019 PMC6724605 10.1091/mbc.E18-10-0629 2 12 0 268 Mice|Animals|*Podosomes|NIH 3T3 Cells|*Rosette Formation|PXN protein, human|Paxillin|Cytoskeletal Proteins|*Transcription Factors|LIM Domain Proteins|Phosphorylation|F-Actin|src-Family Kinases|Cell Adhesion|DNA-Binding Proteins|Fibroblasts|Cell Movement|Actin Cytoskeleton|3T3 Cells|INF2 protein, mouse 260 INF2 30741413 J. Cell. Physiol. 2019 10.1002/jcp.28287 2 2 0 268 *Mitochondrial Dynamics|*MAP Kinase Signaling System|*Apoptosis|Mitochondria|Mitochondrial Proteins|Cell Survival|Microfilament Proteins|Oxidative Stress|Cell Line, Tumor|Bioenergetics|*Thyroid Cancer 260 INSL4 31109993 J. Bacteriol. 2019 PMC6620407 10.1128/JB.00165-19 1 0 0 17 O Antigen|Pseudomonas aeruginosa|Bacterial Proteins|Lipopolysaccharides|Bacteria|Gram Negative Bacteria 45 insl6 30996253 Mod. Pathol. 2019 PMC7189735 10.1038/s41379-019-0269-x 3 0 0 28 Humans|CD274 protein, human|*B7-H1 Antigen|*Carcinoma, Renal Cell|In Situ Hybridization, Fluorescence|Programmed Cell Death 1 Ligand 2 Protein|JAK2 protein, human|*Janus Kinase 2|*Sarcomas|Kidney Neoplasms|Gene Amplification|Gene Expression Regulation, Neoplastic|*Soft Tissue Neoplasms|Immunohistochemistry|Immunotherapy|Cohort Studies 40 INSRR 31615897 J. Biol. Chem. 2019 PMC6879334 10.1074/jbc.RA119.010390 0 0 0 284 Humans|INSR protein, human|insulin receptor-related receptor|*Receptor, Insulin|*Alkali|Scattering, Small Angle|X-Ray Diffraction|Antigens, CD|Protein Domains|Protein Binding|Insulin|Balance, Acid-Base|HEK293 Cells|FN1 protein, human|Fibronectin|Models, Molecular|Hydrogen-Ion Concentration 86 INSRR 31580704 J Athl Train 2019 PMC6863694 10.4085/1062-6050-330-18 0 0 0 284 Male|Humans|Female|*Basketball|*Secondary School|Athletic Injuries|Brain Concussion|Athletes|Universities|Sprains and Strains|Students|*Boys|Incidence 86 INSRR 31353211 J. Pharmacol. Sci. 2019 10.1016/j.jphs.2019.07.002 0 2 0 284 Chlorocebus aethiops|Animals|*Insulin Secretion|insulin receptor-related receptor|*Glucose|*Receptor, Insulin|*Endocytosis|Insulin-Secreting Cells|rab27 GTP-Binding Proteins|Insulin|rab GTP-Binding Proteins|Guanosine Diphosphate|Exocytosis|Plasma Membrane|GTPase Activating Protein|COS Cells|Microfilament Proteins|Guanine Nucleotide Exchange Factor 86 INSRR 31201624 Dokl. Biochem. Biophys. 2019 10.1134/S1607672919020017 0 0 0 284 Cricetinae|Animals|insulin receptor-related receptor|*Receptor, Insulin|CHO Cells|Recombinant Proteins|Insulin|Phosphorylation|Signal Transduction|Transfection|Kinetics|Tyrosine 86 insuline 31697573 Appl Physiol Nutr Metab 2019 10.1139/apnm-2019-0359 0 0 0 0 Adult|Male|Humans|Female|*Artificial Sweeteners|Aspartame|Insulin|trichlorosucrose|Sucrose|Non-Nutritive Sweeteners|Glucagon-Like Peptide 1|Blood Glucose|Glucose Tolerance Test|Glucose|*Cross-Over Studies|*Carbohydrate Metabolism|Body Mass Index 267 insuline 31630987 Can J Diabetes 2019 10.1016/j.jcjd.2019.08.003 0 0 0 0 Adult|Humans|Adolescent|*Diabetes Mellitus, Type 1|*Prevalence|*Insulin Infusion Systems|*Hyperglycemia|Blood Glucose|Hypoglycemic Agents|Insulin|Circadian Rhythm 267 insuline 31618605 Appl Physiol Nutr Metab 2019 10.1139/apnm-2019-0559 0 0 0 0 Humans|Male|*Blood Glucose|*Breakfast|*Appetite|*Diabetes Mellitus, Type 2|*Prunus dulcis|*Cross-Over Studies|*Meal|Postprandial Period|Insulin|Glycemic Index|Glucagon-Like Peptide 1|*Macronutrient|Appetite Regulation|Energy Intake|Hypoglycemia|Bread 267 insuline 31466724 Ann Cardiol Angeiol (Paris) 2019 10.1016/j.ancard.2019.07.004 0 0 0 0 *Hypotension, Orthostatic|Diabetic Autonomic Neuropathy|Blood Pressure|Diabetes Mellitus, Type 2|Posture|Risk Factors 267 insuline 31416695 Can J Diabetes 2019 10.1016/j.jcjd.2019.05.015 2 0 0 0 Adult|Humans|*Diabetes Mellitus, Type 1|*Insulin Infusion Systems|Hypoglycemia|Blood Glucose|*High-Intensity Intermittent Exercise|Insulin|Hypoglycemic Agents|Exercise|Cross-Over Studies 267 insuline 31256905 Can J Diabetes 2019 10.1016/j.jcjd.2019.04.012 0 0 0 0 Adult|Humans|*Insulin Glargine|*Diabetes Mellitus, Type 2|Canada|Hypoglycemia|Hypoglycemic Agents|Insulin, Isophane|Glycated Hemoglobin A|Diabetes Mellitus, Type 1|Blood Glucose|Retrospective Studies|Outcome Assessment, Health Care|Registries 267 insuline 31112659 Appl Physiol Nutr Metab 2019 10.1139/apnm-2019-0193 0 1 0 0 Vitamin D|Vitamin D Deficiency|Vitamin D3 24-Hydroxylase|Cholestanetriol 26-Monooxygenase|25-Hydroxyvitamin D3 1-alpha-Hydroxylase|Vitamins|Receptors, Calcitriol|Cytochrome P450 Family 2|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype 267 insuline 31067999 J Diabetes Sci Technol 2019 PMC6835184 10.1177/1932296819842151 0 0 0 0 Humans|*Insulin Glargine|Insulin, Long Acting|Insulin Infusion Systems|Diabetes Mellitus, Type 1|Insulin|Hypoglycemic Agents|Blood Glucose|Glycated Hemoglobin A 267 insuline 31063309 Arch Argent Pediatr 2019 10.5546/aap.2019.eng.e232 0 0 0 0 Pregnancy|Adult|Humans|Female|Prenatal Nutritional Physiological Phenomena|Fetal Development|Metabolic Syndrome|Maternal Nutritional Physiological Phenomena|Prenatal Exposure Delayed Effects|Obesity|Epigenesis, Genetic|Nutrition Disorders|Pregnancy Complications|Nutritional Status|Cardiovascular Diseases|*Parturition|High Blood Pressure|Fetus 267 insuline 30872107 Can J Diabetes 2019 10.1016/j.jcjd.2019.01.004 2 0 0 0 Adult|Humans|*Insulin Aspart|*Diabetes Mellitus, Type 2|Canada|insulin degludec, insulin aspart drug combination|*Insulin, Long-Acting|B-insulin|*Insulin|Blood Glucose|Glycated Hemoglobin A|Diabetes Mellitus, Type 1|*Time, Meal|Hypoglycemic Agents|Postprandial Period|Hypoglycemia|Hyperglycemia|*Drug Combinations|Insulin, Regular, Human|Double-Blind Method 267 insuline 30794429 Appl Physiol Nutr Metab 2019 10.1139/apnm-2018-0549 0 0 0 0 Adult|Child|Humans|Adolescent|*Snacks|*Blood Glucose|*Postprandial Period|Satiation|Appetite|Insulin|C Peptide|Energy Intake|Glucagon-Like Peptide 1|Eating|Body Mass Index|Obesity|Dietary Carbohydrates|Overweight|Yogurt|Design, Crossover 267 insuline 30755355 J. Diabetes Complicat. 2019 10.1016/j.jdiacomp.2018.12.017 1 0 0 0 Humans|Female|Male|*Diabetes Mellitus|Kidney Transplantation|Risk Factors|Postoperative Complications 267 INVS 31706999 Gene 2019 10.1016/j.gene.2019.144229 0 0 0 384 Humans|Child|Adolescent|Nephronophthisis 2|*Codon, Nonsense|Homozygote|*RNA Splicing|Kidney|Transcription Factors|Mutation|Polycystic Kidney Diseases|Phenotype|End Stage Kidney Disease|Kinesin 684 INVS 31672706 J. Cell Biol. 2019 PMC7039206 10.1083/jcb.201812044 2 0 0 384 *Transport Vesicles|*Biological Transport|Golgi Apparatus|Intracellular Membranes|rab GTPases|TYRP1 protein, human|*Membrane Glycoproteins|Protein Transport|*Tumor|Neoplasm Proteins|Cell Movement|Organelles 684 INVS 31635528 Pediatr. Dev. Pathol. 2019 10.1177/1093526619881541 0 0 0 384 Humans|Infant|Female|Infant, Newborn|Cystic Renal Disease|Cilia|Nuclear Proteins|NIMA-Related Kinases|Carrier Proteins|Transcription Factors|Kidney|Protein Kinases|Kinesin|Mutation|Failure, Renal 684 INVS 31438536 Int J Mol Sci 2019 PMC6747265 10.3390/ijms20174081 1 1 0 384 *Zea mays|*beta-Fructofuranosidase|*Droughts|Plant Leaves|Abscisic Acid|Gene Expression Regulation, Plant|Vacuoles|Cell Wall|Water 684 INVS 31146441 Int J Environ Res Public Health 2019 PMC6603717 10.3390/ijerph16111901 0 0 0 384 Adult|Humans|Cross-Sectional Studies|*Air Pollution|Nitrogen Dioxide|Air Pollutants|Particulate Matter|Environmental Exposure|*Socioeconomic Status|*Respiratory Physiological Phenomena 684 INVS 31131822 Clin. Nephrol. 2019 10.5414/CN109571 1 0 0 384 Humans|*Whole Exome Sequencing|*Mutation|Homozygote|Phenotypes|Adaptor Proteins, Signal Transducing|Heterozygote|Kidney Failure, Chronic|Membrane Proteins|*Polycystic Kidney Diseases|Pedigree|China 684 INVS 31097251 Harmful Algae 2019 10.1016/j.hal.2019.01.004 0 0 0 384 *Plankton|Argentina|Cylindrospermopsis raciborskii|Dolichospermum circinale|Dolichospermum spiroides|Raphidiopsis mediterranea|*Cyanobacteria|Eutrophication|Lakes|Cylindrospermopsis|Microcystis aeruginosa|Rivers|Nitrogen 684 INVS 30836959 BMC Genomics 2019 PMC6402180 10.1186/s12864-019-5564-x 4 0 0 384 Horses|Animals|*Multifactorial Inheritance|*Homozygote|Genotype|Genome|Genetics, Population|Inbreeding|Phenotype|Polymorphism, Single Nucleotide|*Running|Gene Ontology 684 INVS 30598432 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6338837 10.1073/pnas.1804042116 2 4 0 384 Mice|Animals|*Hedgehog Proteins|SMO protein, human|*Smoothened Receptor|*Signal Transduction|Patched-1 Receptor|Cilium|Cyclic AMP-Dependent Protein Kinases|Phosphorylation|Cell Membrane|NIH 3T3 Cells 684 IPO7 31505435 Clin Neurol Neurosurg 2019 10.1016/j.clineuro.2019.105488 1 0 0 322 Child|Humans|Neoplasm Recurrence, Local|Familial ependymoma|*Ependymoma|*Prognosis|Immunohistochemistry|ASAH1 protein, human|*Acid Ceramidase|Brain Neoplasms|Biomarkers, Tumor|*Proteomics|*Protein Processing, Post-Translational|GNAO1 protein, human|GTP-Binding Protein alpha Subunits, Gi-Go 55 IPO7 31385665 Cell. Physiol. Biochem. 2019 10.33594/000000144 1 5 0 322 Humans|*Casein Kinase II|*Phosphorylation|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|*Mitogen-Activated Protein Kinases|Mitogen-Activated Protein Kinase 1|*Protein Transport|CSNK2A1 protein, human|Cell Nucleus|Active Transport, Cell Nucleus|Cytoplasm|HeLa Cells 55 IPO7 31090959 J. Cell. Biochem. 2019 10.1002/jcb.28890 1 3 0 322 Humans|Animals|Mice|*Nuclear Localization Signals|KPNB1 protein, human|*beta Karyopherins|*Active Transport, Cell Nucleus|Importin|alpha Karyopherins|Cell Nucleus|Amino Acid Sequence|Protein Binding|*Oxidative Stress|NUAK1 protein, human|Protein Kinases|Repressor Proteins|NUAK1 protein, mouse 55 IRG1 31736414 Physiol. Genomics 2019 PMC6962593 10.1152/physiolgenomics.00101.2019 0 0 0 3025 Humans|Child|Mice|Animals|Child, Preschool|TLR4 protein, human|*Toll-Like Receptor 4|*Transcriptome|*Respiratory Syncytial Virus|*Strain, Inbred Mouse|Respiratory Syncytial Virus Infections|*Lung|Bronchoalveolar Lavage Fluid|Signal Transduction|Innate Immune Response 90 IRG1 31719183 mBio 2019 PMC6851286 10.1128/mBio.02629-19 0 4 0 3025 *Legionella pneumophila|*Interferon-gamma|NOS2 protein, human|*Nitric Oxide Synthase Type II|Legionnaires' Disease|*Cytoplasm|*Protein Transport|Macrophages|Host-Pathogen Interactions|Immunity, Innate|Apoptosis Regulatory Proteins|Bacterial Proteins|Signal Transduction 90 IRG1 31671694 Molecules 2019 PMC6864543 10.3390/molecules24213919 2 0 0 3025 *Oils, Volatile|Mastic Resin|Pistacia|Plant Oils|Monoterpenes|Cell Line, Tumor|Anti-Inflammatory Agents 90 IRG1 31548418 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6789909 10.1073/pnas.1908770116 2 0 0 3025 90 IRG1 31270271 Sci Transl Med 2019 PMC6784538 10.1126/scitranslmed.aav4634 5 0 0 3025 CFTR protein, human|*Cystic Fibrosis Transmembrane Conductance Regulator|Pseudomonas Infections|Cystic Fibrosis|Pseudomonas aeruginosa|PTEN protein, human|*PTEN Phosphohydrolase|Epithelial Cells|Signal Transduction|Cells, Cultured|Plasma Membrane 90 IRG1 31165150 J. Radiat. Res. 2019 PMC6640901 10.1093/jrr/rrz024 0 1 0 3025 Mice|Animals|TLR5 protein, human|*Toll-Like Receptor 5|*Total Body Irradiation|Acute Radiation Syndrome|Radiation-Protective Agents|Hematopoietic System|Radiosensitivity|*Radiation Protection|Gamma Rays|Mice, Inbred C57BL|Cell Proliferation|Bone Marrow|Signal Transduction|Granulocyte Colony-Stimulating Factor|Cell Death|Irg1 protein, mouse|Hydro-Lyases 90 IRG1 30841905 Vet. Res. 2019 PMC6404279 10.1186/s13567-019-0638-y 4 32 0 3025 Animals|*Avian Leukosis Virus|*Chickens|Avian Leukosis|*Macrophage|Gene Expression Regulation|Transcriptome Analysis|Innate Immune Responses|Gene Ontology|MicroRNAs|Suppressor of Cytokine Signaling Proteins|Cell Line 90 IRG1 30669987 BMC Genomics 2019 PMC6341744 10.1186/s12864-019-5450-6 4 0 0 3025 *Mycobacterium tuberculosis Infection|Mycobacterium tuberculosis|*Macrophage|Gene Expression Regulation|*Regulatory Sequences, Nucleic Acid|Cell Line 90 IRG1 30635240 Immunity 2019 PMC6342485 10.1016/j.immuni.2018.11.017 17 3 0 3025 Mice|Animals|Zika Virus|Zika Virus Infection|RIPK1 protein, human|*Receptor-Interacting Protein Serine-Threonine Kinases|RIPK3 protein, human|Virus Replication|Necrosis|*Neurons|*Antiviral Agents|*Nucleotides|Cell Death|Mice, Knockout|Apoptosis|Central Nervous System|Disease Models, Animal|Zbp1 protein, mouse|Glycoproteins|Ripk3 protein, mouse 90 IRGC 31884574 Community Ment Health J 2019 PMC7089884 10.1007/s10597-019-00537-y 0 0 0 17 Male|Humans|*Antipsychotic Agents|*Metabolic Syndrome|*Retrospective Studies|*Risk Factors|Prospective Studies|Psychotic Disorder|Obesity|Body Mass Index|Hypertension|Prevalence|Blood Glucose|3'-(1-butylphosphoryl)adenosine|Qatar 32 IRGC 31811315 Theor. Appl. Genet. 2019 10.1007/s00122-019-03501-2 0 0 0 17 *Oryza|Xanthomonas oryzae|*Chromosome Mapping|Xanthomonas|Genes, Plant|Disease Resistance|Quantitative Trait Loci|Genetic Linkage|Plant Diseases|Chromosomes, Plant|Crosses, Genetic|Genetic Markers|*Bacterial Genes|Recessive Gene|Phenotype 32 IRGC 31481846 Breed. Sci. 2019 PMC6711740 10.1270/jsbbs.19002 0 0 0 17 Quantitative Trait Loci|Chromosomes, Plant|Genome, Plant|Chromosome Mapping|Oryza|Genetic Background|Phenotype|Polymorphism, Genetic 32 IRGM 31844038 Med. Sci. Monit. 2019 PMC6929548 10.12659/MSM.917244 0 0 0 334 Humans|*Crohn Disease|Single Nucleotide Polymorphism|Asian|Genetic Predisposition to Disease|TNFSF15 protein, human|Tumor Necrosis Factor Ligand Superfamily Member 15|Genetic Association Studies|Gene Frequency|Case-Control Studies|Genotype|Rectal Fistula|Allele|Odds Ratio|China 248 IRGM 31833533 Nanoscale 2019 10.1039/c9nr06691h 0 0 0 334 *Biomineralization|Manganese Compounds|Hydrogen Peroxide|Oxides|Glucose Oxidase|Quantum Dots|Fluorescence|Biosensing Techniques|Limit of Detection|*Calcification, Physiologic|Nanoparticles|Blood Glucose|Glucose|Fluorometry 248 IRGM 31714311 Ann. Surg. 2019 10.1097/SLA.0000000000003660 0 0 0 334 *Crohn Disease|*Recurrence|*Colectomy|Genetic Predisposition to Disease|Nod2 Signaling Adaptor Protein|Polymorphism, Single Nucleotide|Autophagy-Related Proteins|Gene Frequency|Genotype|Phenotype|*Intestines|Case-Control Studies|GTP-Binding Proteins|Carrier Proteins 248 IRGM 31694333 Cells 2019 PMC6912674 10.3390/cells8111394 2 1 0 334 Humans|Crohn's Disease|*Macrophages|Escherichia coli Infections|Colitis, Ulcerative|Escherichia coli|Bacterial Adhesion|Autophagy-Related Proteins|Intestinal Mucosa|Carrier Proteins 248 IRGM 31654602 J Dig Dis 2019 10.1111/1751-2980.12829 0 0 0 334 Humans|*Crohn Disease|Autophagy-Related Proteins|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|GTP-Binding Proteins|Carrier Proteins|*Genes, Regulator|IRGM protein, human|ATG16L1 protein, human 248 IRGM 31612000 Oncol Lett 2019 PMC6781648 10.3892/ol.2019.10829 0 0 0 334 Humans|Female|*Prognosis|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Immunohistochemistry|Biomarkers, Tumor|AGBL2 protein, human|Carboxypeptidases 248 IRGM 31318632 Autophagy 2019 PMC7144873 10.1080/15548627.2019.1643184 1 6 0 334 Humans|Animals|*Peste-des-petits-ruminants virus|Peste-des-Petits-Ruminants|*Autophagy|Autophagosomes|Cell Signaling|*Carrier Proteins|Phosphorylation|Virus Replication|RNA, Small Interfering|HeLa Cells|Protein Binding|HEK293 Cells 248 IRGM 31286804 Autophagy 2019 PMC6984609 10.1080/15548627.2019.1635384 5 0 0 334 *Gastrointestinal Microbiome|Genome-Wide Association Study|*Autophagy|*Inflammatory Bowel Disease|Inflammation|Signal Transduction|Crohn's Disease|Intestines 248 IRGM 31177914 Autophagy 2019 PMC6693461 10.1080/15548627.2019.1628544 1 10 0 334 Mice|Animals|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|*Sequestosome-1 Protein|Dextran Sulfate|Colitis|Autophagy|Crohn's Disease|THP-1 Cells|Disease Models, Animal|Sqstm1 protein, mouse|Nlrp3 protein, mouse 248 IRX3 31839007 J Neurodev Disord 2019 PMC6913030 10.1186/s11689-019-9294-9 0 0 0 167 Animals|Mice|*Down Syndrome|*Neurons|*Disease Models, Animal|Neurogenesis|Mice, Transgenic|Mice, Inbred C57BL|*Neuroglia|Hippocampus|Cognition 185 IRX3 31771407 Adipocyte 2019 PMC6948981 10.1080/21623945.2019.1693745 2 2 0 167 Humans|Male|Adolescent|Longitudinal Studies|Iran|*Overweight|*Obesity|*Energy Intake|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|*Genotype|Body Weight|Body Mass Index|*Gene Expression|Homeodomain Proteins|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Transcription Factors|Nutrients|IRX3 protein, human|FTO protein, human 185 IRX3 31751577 Metab. Clin. Exp. 2019 10.1016/j.metabol.2019.154014 0 0 0 167 Humans|Mice|Animals|*Genes, Homeobox|*Adipogenesis|Adipocyte|Thermogenesis|Adipose Tissue, White|*DNA-Binding Proteins|Cell Differentiation|Transcription Factors|Body Weight|Obesity|Cells, Cultured|IRX3 protein, human|Homeodomain Proteins|Irx3 protein, mouse 185 IRX3 31623237 Pharmaceuticals (Basel) 2019 PMC6958487 10.3390/ph12040156 0 0 0 167 Animals|Mice|Humans|Neurogenesis|NEUROG1 protein, human|Basic Helix-Loop-Helix Transcription Factors|Zebrafish|Zebrafish Proteins|Neurons|Mesencephalon|Neural Stem Cells|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Hindbrain|Cell Differentiation|Animals, Genetically Modified|In Situ Hybridization 185 IRX3 31538128 Arch Med Sci Atheroscler Dis 2019 PMC6749179 10.5114/amsad.2019.87545 0 0 0 167 *Body Weight|Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Homeodomain Proteins|Transcription Factors|Polymorphism, Single Nucleotide 185 IRX3 31401395 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109291 0 3 0 167 Animals|Mice|*RNA|Phosphatidylinositol 3-Kinases|*Bone Marrow Cell|Hematopoiesis|*Transcriptome Analysis|Hematopoietic Stem Cells|colla corii asini|*Gelatin|5 Fluorouracil|Sequencing, RNA|Cell Differentiation|Traditional Chinese Medicine|Gene Expression Profiles|Drugs, Chinese Herbal|Proteins|China 185 IRX3 31281828 Int J Genomics 2019 PMC6589220 10.1155/2019/5070975 0 1 0 167 Swine|Animals|*RNA, Long Noncoding|Tibet|*Fatty Acids|*Phenotype|Sus scrofa|*CD36 Antigens 185 IRX3 31126299 J Transl Med 2019 PMC6534854 10.1186/s12967-019-1921-4 1 0 0 167 Humans|Male|Adolescent|*Overweight|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|*Genotype|*Lifestyle|Body Mass Index|Pediatric Obesity|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Homeodomain Proteins|*Gene Expression|Transcription Factors|IRX3 protein, human|FTO protein, human 185 IRX3 30840652 PLoS ONE 2019 PMC6402656 10.1371/journal.pone.0212367 1 3 0 167 Male|Female|Humans|Mice|Animals|*Mice, Nude|*Ovary|Sex Differentiation|Testis|Sex Determination Processes|Sertoli Cells|Sex-Determining Region Y Protein|Gonads|SOX9 Transcription Factor|Forkhead Box Protein L2|Gene Expression Regulation, Developmental|*Virilism|Transcriptome Analyses 185 IRX3 30713021 Obes Res Clin Pract 2019 10.1016/j.orcp.2019.01.005 1 0 0 167 Child|Adolescent|Humans|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Adiposity|Genetic Predisposition to Disease|Body Mass Index|*Phenotypes|Pediatric Obesity|Genetic Association Studies|Polymorphism, Single Nucleotide|Genotype|Anthropometry|Brazil|IRX3 protein, human|Transcription Factors|Homeodomain Proteins|FTO protein, human 185 IRX4 30862593 World Neurosurg 2019 10.1016/j.wneu.2019.02.184 0 0 0 60 Female|Adolescent|Humans|*Scoliosis|*Kyphosis|Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genotype|Alleles|Case-Control Studies 63 ISL2 31575648 Development 2019 PMC6826036 10.1242/dev.181750 0 0 0 74 Transcription Factor|Receptor, trkC|Ganglia, Spinal|Sensory Receptor Cells|Homeodomain Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Core Binding Factor Alpha 3 Subunit|Receptor, trkB|Transcription Factor|Receptor, trkC|Ganglia, Spinal|Sensory Receptor Cells|Homeodomain Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Core Binding Factor Alpha 3 Subunit|Receptor, trkB 55 ISL2 30788856 Proteins 2019 10.1002/prot.25675 0 1 0 74 LIM Domain Proteins|LIM-Homeodomain Proteins|DNA-Binding Proteins|Transcription Factors|*Mutation|Protein Structure, Tertiary|Protein Binding|Binding Sites|Protein Conformation|Two-Hybrid System Techniques|Crystallography, X-Ray|Amino Acid Sequence|Models, Molecular 55 ISM1 31513891 Mol. Cell. Probes 2019 10.1016/j.mcp.2019.101445 1 7 0 121 *Cell Proliferation|*Apoptosis|*Colon Cancer|MicroRNAs|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Down-Regulation|Cell Line, Tumor|Up-Regulation|Cell Movement|Adenocarcinoma 26 ISM1 31207319 Cancer Lett. 2019 10.1016/j.canlet.2019.06.007 0 3 0 121 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Hepatocellular Cancer|MIRN1307 microRNA, human|*MicroRNAs|Cell Proliferation|*Disease Progression|Gene Expression Regulation, Neoplastic|Hep G2 Cells|Carcinogenesis|Apoptosis|*Neoplastic Processes|Cell Movement|Cell Line, Tumor|Xenograft|RNA, Circular 26 ISM1 31171630 J. Cell Biol. 2019 PMC6605798 10.1083/jcb.201801081 0 4 0 121 Animals|Nodal Protein|*Morphogenesis|*Signal Transduction|Body Patterning|Mesoderm|Transforming Growth Factor beta|Xenopus Proteins|Xenopus laevis|Activins|Gene Expression Regulation, Developmental 26 ISM1 31000732 Sci Rep 2019 PMC6472367 10.1038/s41598-019-41525-2 1 0 0 121 Humans|*Aldosterone|*Transcriptome|*Adrenocortical Adenoma|Hyperaldosteronism|Adrenal Cortex Neoplasms|G Protein-Coupled Inwardly-Rectifying Potassium Channels|*Whole Exome Sequencing|Plasma Membrane Calcium-Transporting ATPases|Adrenal Glands|CACNA1D protein, human|Calcium Channels, L-Type|Mutations|*Sequencing, RNA|*Base Sequence|Adenomas|CTNNB1 protein, human|beta Catenin|Sodium-Potassium-Exchanging ATPase 26 isx 31814833 Stem Cells Int 2019 PMC6878789 10.1155/2019/3726392 3 2 0 94 *miRNAs|*Myocardial Infarction|*Extracellular Vesicles|*Fibrosis|Myocytes, Cardiac|Stem Cell Transplantation|Stem Cells|*Morphogenesis|Cell Differentiation|Heart Failure|Cell Survival|*Multipotent Stem Cells|Cells, Cultured 76 isx 31767563 Clin. Cancer Res. 2019 10.1158/1078-0432.CCR-19-0656 0 4 0 94 Humans|Circulating Tumor Cells|Biomarkers, Tumor|Prognosis|Bone Marrow Neoplasms|*Neoplasms, Second Primary|Bone Marrow|*Neuroblastoma 76 isx 31538956 IET Syst Biol 2019 10.1049/iet-syb.2019.0025 1 0 0 94 Humans|*Thyroid Cancer, Papillary|*Down-Regulation|Prospective Studies|*miRNA|Carcinoma, Thyroid|Carcinoma, Papillary|Gene Expression Regulation, Neoplastic|LILRB1 protein, human|*Leukocyte Immunoglobulin-like Receptor B1|Cell Proliferation|Lymphatic Metastasis|*Antigens, CD|Cell Movement|Cell Line, Tumor|Apoptosis|Disease Progression|MIRN7 microRNA, human 76 isx 31438980 Radiat Oncol 2019 PMC6704696 10.1186/s13014-019-1344-7 1 0 0 94 *Flow Cytometry|DNA Breaks, Double-Stranded|DNA Repair|Histones|Dose-Response Relationship, Radiation|DNA Damage|Gamma Rays|Lymphocytes 76 isx 31309185 Eur Oral Res 2019 PMC6612758 10.26650/eor.20196934 0 0 0 94 Child|Humans|*Maxillary Sinus|*Molar|Radiography, Panoramic|Bicuspid|Maxilla|Tooth Extraction|Cephalometry 76 isx 31174057 Transl Oncol 2019 PMC6556561 10.1016/j.tranon.2019.05.002 0 1 0 94 Mice|Humans|Animals|*Genes, Homeobox|Carcinoma, Pancreatic Ductal|Pancreatic Neoplasms|*Disease Progression|Genes, ras|Mice, Transgenic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Cyclin-Dependent Kinase Inhibitor p16|Signal Transduction|*Hypoxia|Intestines|Isx protein, human|Transcription Factors|Homeodomain Proteins 76 isx 31063959 Spectrochim Acta A Mol Biomol Spectrosc 2019 10.1016/j.saa.2019.04.064 0 0 0 94 *Isoxsuprine|Least Squares|Neural Network Model|Algorithm|Principal Component Analysis|Analysis of Variance|Calibration|Spectrophotometry, Ultraviolet|Spectrophotometry 76 isx 30738022 Chem. Biol. Interact. 2019 10.1016/j.cbi.2019.02.002 1 3 0 94 Rats|Animals|*Mitochondria, Liver|1,2,3,4-tetrahydroquinoline|*Carcinoma, Hepatocellular|*Hep G2 Cells|*Mitochondria|*Quinolines|*Bioenergetics|Liver Neoplasms|Reactive Oxygen Species|Oxidative Stress|Cell Survival|Oxygen Consumption|Succinate Dehydrogenase|*Isoxazoles 76 ITIH5 31887566 Cortex 2019 10.1016/j.cortex.2019.11.006 1 0 0 60 Humans|Genome-Wide Association Study|Autism Spectrum Disorder|*Temporal Lobe|*Intelligence|Dyslexia|Auditory Cortex|Functional Laterality|*Academic Success|Schizophrenia|Magnetic Resonance Imaging|Brain|Multifactorial Inheritance|*Neurodevelopmental Disorders|Autism|ITIH5 protein, human|Proteinase Inhibitory Proteins, Secretory 37 ITIH5 31741713 Oncotarget 2019 PMC6849652 10.18632/oncotarget.27303 1 0 0 60 *DNA Methylation|*Early Detection of Cancer|*Liquid Biopsy|Promoter Regions, Genetic|Epigenetic|Biomarkers, Tumor|Epigenesis, Genetic|Proteinase Inhibitory Proteins, Secretory|Gene Expression Regulation, Neoplastic|Cell Free DNA 37 ITM2A 31443152 Int J Mol Sci 2019 PMC6721001 10.3390/ijms20163966 1 0 0 90 Female|Swine|Animals|*Ovary|*Transcriptome|*Granulosa Cells|Ovarian Follicle|Oogenesis|*Cell Differentiation|*Morphogenesis|Ovulation|*Hair Follicle|Cell Proliferation|Cells, Cultured|*Biomarkers|*Marital Status 47 ITM2A 31438969 Cell Commun. Signal 2019 PMC6704577 10.1186/s12964-019-0422-7 2 3 0 90 Female|Humans|*Cell Proliferation|*Autophagy|Cell Line, Tumor|Drug Resistance, Neoplasm|*Cell Cycle|Carcinoma, Ovarian Epithelial|Ovarian Cancer|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Survival|Membrane Proteins|ITM2A protein, human 47 ITM2A 31335995 Cancer Sci. 2019 PMC6726690 10.1111/cas.14138 6 0 0 90 Humans|*Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|RNA, Long Noncoding|MicroRNAs|mRNA|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate|Receiver Operating Characteristic|Risk Factors|ITM2A protein, human|Membrane Proteins|CPEB3 protein, human|RNA-Binding Proteins|STRN3 protein, human 47 ITM2A 31333881 J Adv Res 2019 PMC6614546 10.1016/j.jare.2019.05.006 3 0 0 90 Adult|Humans|*Genes, Homeobox|*Leukemia, Myeloid, Acute|Mutations|Nuclear Proteins|Genotype|Hematopoietic Stem Cells|Cohort Studies 47 ITM2A 30740043 Front Mol Neurosci 2019 PMC6355686 10.3389/fnmol.2019.00005 1 1 0 90 *Gene Knockout Techniques|Kv Channel-Interacting Proteins|Calcium Signaling|Repressor Proteins 47 ITM2C 31200545 Viruses 2019 PMC6631246 10.3390/v11060549 0 1 0 80 Hepatitis C virus|Hepatitis C|Virus Replication|Long Non-Coding RNA|Cell Line, Tumor|Signal Transduction 27 ITM2C 30888555 Mol. Biol. Rep. 2019 10.1007/s11033-019-04663-4 0 0 0 80 Humans|*Prognosis|Bayes Theorem|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Receptors, Estrogen|Gene Expression Profiling|Biomarkers, Tumor|Protein Interaction Maps|Computational Biology|mRNA|Transcriptome|Kaplan-Meier Estimate|CPEB2 protein, human|RNA-Binding Proteins|ANXA9 protein, human|Annexins 27 ITM2C 30721158 JCI Insight 2019 PMC6483196 10.1172/jci.insight.126125 12 1 0 80 Humans|Mice|Child|Animals|Proteomics|*Pulmonary Fibrosis|*Endoplasmic Reticulum Stress|Alveolar Epithelial Cells|Pulmonary Surfactant-Associated Protein C|Lung|Interstitial Lung Disease|Pulmonary Alveoli|Endoplasmic Reticulum|Bronchoalveolar Lavage Fluid|Mutation|Apoptosis|Protein Processing, Post-Translational|SFTPC protein, human 27 JAZF1 31819531 Onco Targets Ther 2019 PMC6897071 10.2147/OTT.S230597 0 9 0 189 *Thyroid Cancer, Papillary|*Cell Proliferation|*Apoptosis|Carcinoma, Papillary|Thyroid Neoplasms|Cell Movement|Carcinoma|Cell Line, Tumor|NF-kappa B|Signal Transduction 205 JAZF1 31615558 Diagn Pathol 2019 PMC6792225 10.1186/s13000-019-0897-y 0 0 0 189 Humans|Female|*Sarcoma, Endometrial Stromal|*Fluorodeoxyglucose F18|Tomography, X-Ray Computed|*Endometrial Stromal Tumors|*Positron Emission Tomography|Endometrial Neoplasms|Neoplasm Proteins|Polycomb Repressive Complex 2|Gene Fusion|In Situ Hybridization, Fluorescence|JAZF1 protein, human|SUZ12 protein, human 205 JAZF1 31357957 BMC Cancer 2019 PMC6664777 10.1186/s12885-019-5929-1 3 10 0 189 *Vimentin|*Stomach Neoplasms|CDH1 protein, human|*E Cadherin|*Cell Migration|*Antigens, CD|Neoplasm Invasiveness|MicroRNAs|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Proliferation|*Transcription Factors|Prognosis|Cell Line, Tumor|Lymphatic Metastasis|*Intermediate Filaments|Apoptosis 205 JAZF1 31281901 Sci Adv 2019 PMC6609211 10.1126/sciadv.aax2887 4 16 0 189 *Polycomb Repressive Complex 2|*Methylation|Histones|Chromatin|Glioma|Lysine 205 JAZF1 31177938 Cell Cycle 2019 PMC6619954 10.1080/15384101.2019.1629774 0 2 0 189 Rats|Animals|*Myocardial Reperfusion Injury|Endothelial Cells|*Proto-Oncogene Proteins c-akt|Diabetes Mellitus, Type 2|*Signal Transduction|*Myocardial Ischemia|*Heart|*Cell Proliferation|*Myocardial Reperfusion|*Neovascularization, Pathologic|Apoptosis|*Coronary Artery Disease|Myocardium|Endothelium, Vascular|Cell Hypoxia|*Ischemia|Cells, Cultured 205 JAZF1 30940621 Br J Ophthalmol 2019 PMC7041504 10.1136/bjophthalmol-2018-313200 0 0 0 189 Child|Humans|*Arthritis, Juvenile|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Uveitis|Gene Frequency|Genotype|Case-Control Studies 205 KCNT2 31812952 Aging (Albany NY) 2019 PMC6932877 10.18632/aging.102553 1 0 0 55 Humans|Animals|Auditory Nerve|Inner Hair Cell|Auditory Threshold|Hearing Loss, Noise-Induced|Evoked Potentials, Auditory, Brain Stem|Noise|Synapses|Neurons 56 KCNT2 31557882 Genes (Basel) 2019 PMC6826586 10.3390/genes10100747 3 0 0 55 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Prognosis|*Nevus, Pigmented|*Nevus|Gene Expression Profiling|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|RNA, Messenger|Immunohistochemistry|Software|Microarray Analysis 56 KCNT2 31444905 J. Physiol. (Lond.) 2019 PMC6800802 10.1113/JP278279 0 3 0 55 *Muscle, Smooth, Vascular|*Potassium Channels, Sodium-Activated|Myocytes, Smooth Muscle|Patch-Clamp Techniques|Cells, Cultured 56 KCP 31740422 Clin. Microbiol. Infect. 2019 10.1016/j.cmi.2019.11.011 2 1 0 43 Humans|avibactam, ceftazidime drug combination|*Ceftazidime|avibactam|carbapenemase|*Klebsiella pneumoniae|*Klebsiella|*Azabicyclo Compounds|*beta-Lactamases|*Bacterial Proteins|*Drug Combinations|Klebsiella Infections|Carbapenem-Resistant Enterobacteriaceae|Microbial Sensitivity Tests|Porins|Drug Resistance, Multiple, Bacterial|Anti-Bacterial Agents|*Genomics|Bacteremia 201 KCP 31556162 Skin Res Technol 2019 10.1111/srt.12784 0 0 0 43 Humans|Female|*Body Fat|*Skin|Lymphedema|Body Water|Electric Impedance|Forearm|Arm|Obesity 201 KCP 31490923 PLoS Biol. 2019 PMC6750614 10.1371/journal.pbio.3000437 1 0 0 43 Humans|Animals|Mice|Swine|*Heart|Xenopus laevis|Xenopus|Xenopus Proteins|Amino Acid Sequence|Evolution, Molecular|Conserved Sequence|Phylogeny|Myocardium|Mammals|Species Specificity|Organogenesis|Cardiac Failure|Proteomes 201 KCP 31362492 J. Am. Chem. Soc. 2019 10.1021/jacs.9b06879 0 0 0 43 Molecular Structure|Models, Molecular|Crystallography, X-Ray|Organometallic Compounds|Stereoisomerism|Magnetic Resonance Spectroscopy 201 KCP 31358583 Antimicrob. Agents Chemother. 2019 PMC6761554 10.1128/AAC.01265-19 3 0 0 43 Humans|ceftolozane|*Critical Illness|Prospective Studies|ceftolozane, tazobactam drug combination|*Tazobactam|*Cephalosporins|Penicillanic Acid|Piperacillin|Anti-Bacterial Agents|Microbial Sensitivity Tests|Pseudomonas Infections|Pseudomonas aeruginosa|Monte Carlo Method|Sepsis|Kidney Diseases 201 KCP 31299512 Curr Opin Pharmacol 2019 10.1016/j.coph.2019.05.008 0 0 0 43 Female|Male|*Pruritus|Antipruritics|Serotonin Uptake Inhibitors|Cholestasis 201 KCP 31279852 Int. J. Antimicrob. Agents 2019 10.1016/j.ijantimicag.2019.06.027 0 0 0 43 Male|Humans|*Ticarcillin|*Critical Illness|Tandem Mass Spectrometry|Microbial Sensitivity Tests|Anti-Bacterial Agents|Hemofiltration|Hemodiafiltration|Acute Kidney Injury 201 KCP 31234008 Mol Ther Nucleic Acids 2019 PMC6595412 10.1016/j.omtn.2019.05.011 4 0 0 43 Animals|Rats|MIRN144 microRNA, rat|RNA, Micro|lncRNA|mRNA|Gene Ontology|*Non-Coding RNA|Gene Regulatory Networks|Sequencing, RNA|Gene Expression Profiling|circRNAs|Computational Biology|*Acute Kidney Injury 201 KCP 31090004 Environ Sci Pollut Res Int 2019 10.1007/s11356-019-05311-x 1 0 0 43 Groundwater|Coal Mining|Water Quality|Environmental Monitoring|Water Pollutants, Chemical|Coal|Water|China 201 KCP 31051378 Water Res. 2019 10.1016/j.watres.2019.04.045 0 0 0 43 ferrate ion|*Iron|*Phenols|Water Purification|2-benzylphenol|Benzhydryl Compounds|Water Pollutants, Chemical|clorophene|Dichlorophen|Kinetics|Oxidation-Reduction 201 KCTD12 31565480 Cancer Biol Med 2019 PMC6743620 10.20892/j.issn.2095-3941.2019.0073 0 7 0 183 *Down-Regulation|*CD271|NGFR protein, human|*Receptors, Nerve Growth Factor|*Melanoma|*Nerve Tissue Proteins|Neoplastic Stem Cells|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor 55 KCTD12 31311980 Sci Rep 2019 PMC6635502 10.1038/s41598-019-46655-1 1 5 0 183 *Lithium|*Glycogen Synthase Kinase 3|Receptors, GABA-B|Potassium Channel 55 KCTD12 31197948 CNS Neurosci Ther 2019 PMC6566181 10.1111/cns.13156 3 5 0 183 Humans|Saccharomyces cerevisiae Proteins|Lysosome|Potassium Channels|Autism|Bipolar Disorder|KCTD12 protein, human|Proteins|KCTD7 protein, human|KCTD3 protein, human 55 KCTD12 30886212 Transl Psychiatry 2019 PMC6423133 10.1038/s41398-019-0454-1 1 2 0 183 Adult|Humans|*Genome-Wide Association Study|SNPs|Brain|Thinking|Psychiatric Disorders|Dorsolateral Prefrontal Cortex|Phenotypes|MicroRNAs|United Kingdom|Hungary|KCTD12 protein, human|Proteins|TPH2 protein, human|Tryptophan Hydroxylase|ATXN7L3B protein, human|Transcription Factors|MIRN383 microRNA, human 55 KCTD12 30872078 Cancer Lett. 2019 10.1016/j.canlet.2019.02.050 0 2 0 183 adefovir dipivoxil|*Vemurafenib|*Organophosphonates|*Adenine|*CDC2 Protein Kinase|Lamivudine|Reverse Transcriptase Inhibitors|Proto-Oncogene Proteins B-raf|*Colon Cancer|Hepatitis B virus|Antiviral Agents|Melanoma|Cell Proliferation|*Genes, cdc|Cell Cycle 55 KCTD12 30814734 Nature 2019 PMC6405316 10.1038/s41586-019-0990-0 6 2 0 183 Animals|Humans|Cricetinae|GTP-Binding Protein beta Subunits|GTP-Binding Protein gamma Subunits|Receptors, GABA-B|G Protein-Coupled Inwardly-Rectifying Potassium Channels|Cricetulus|CHO Cells|HEK293 Cells|gamma-Aminobutyric Acid 55 KIAA0196 31814071 Neurol. Sci. 2019 10.1007/s10072-019-04180-z 0 1 0 71 Spastic Paraplegia Type 8|*Spastic Paraplegia, Hereditary|Italy|*Paraplegia|*Mutations|Pedigree|Phenotype|Membrane Proteins|Age of Onset 35 KIAA0196 31645484 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2019 10.11817/j.issn.1672-7347.2019.180360 0 0 0 71 Animals|Humans|*Zebrafish|DNA Copy Number Variations|Zebrafish Proteins|*Organogenesis|Myocytes, Cardiac|Heart Defects, Congenital|Animals, Genetically Modified|Gene Expression Regulation, Developmental|Phenotype|KIAA0196 protein, human|Proteins 35 KIAA0196 31055811 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.06.013 0 0 0 71 Humans|*Spastic Paraplegia, Hereditary|*Mutation|Chinese|Pedigree|Genetic Testing|Proteins|KIAA0196 protein, human 35 KIAA0196 30896870 Mol Med Rep 2019 10.3892/mmr.2019.10043 2 2 0 71 Infant|Humans|*Cleft Lip|Cleft Palate|3C syndrome|Abnormalities, Multiple|*Heart Defects, Congenital|Mutation|DNA Copy Number Variations|Dandy-Walker Syndrome|Heart Septal Defects, Atrial|*Palate|China 35 KLF11 31640084 Cancer Biomark 2019 10.3233/CBM-190199 1 0 0 368 Humans|*Computational Biology|*Prognosis|*Transcription Factors|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|Kruppel-Like Transcription Factors 136 KLF11 31612481 J. Cell. Physiol. 2019 PMC6916361 10.1002/jcp.29067 2 0 0 368 Humans|*Transcriptional Network|*Adenocarcinoma|RNA, Micro|*Colonic Neoplasms|*Disease Progression|Gene Expression Regulation, Neoplastic|RNA, Long Noncoding|Gene Ontology|Gene Expression Profiling|Genes, Regulator|Computational Biology|Transcription Factors|RNA, Messenger|Biomarkers, Tumor|Colon|CTHRC1 protein, human|Extracellular Matrix Proteins 136 KLF11 31498019 Int. J. Radiat. Biol. 2019 10.1080/09553002.2019.1665213 0 2 0 368 136 KLF11 31390356 PLoS ONE 2019 PMC6685631 10.1371/journal.pone.0220441 1 0 0 368 Swine|Animals|*Brassica napus|*Transcriptome|Norway|*Meat|*Brassica rapa|Animal Feed|Diet|Body Composition|*Muscle, Skeletal|*Meal|Soy Bean|Genes, Regulator 136 KLF11 31336727 Biomolecules 2019 PMC6681357 10.3390/biom9070274 2 5 0 368 Mice|Rats|Animals|*Adipogenesis|3T3-L1 Cells|Adipocytes|Diet, High-Fat|Obesity|CCAAT-Enhancer-Binding Protein-alpha|Cell Differentiation|Adipose Tissue|PPAR gamma|MicroRNAs|*tRNA|Cell Proliferation|RNA, Messenger|Epigenesis, Genetic 136 KLF11 31146115 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.108985 1 1 0 368 Humans|*Neuroma, Acoustic|Proteomics|Quality of Life|Neoplasm Recurrence, Local|Cerebellopontine Angle|TYRP1 protein, human|*Membrane Glycoproteins|Retrospective Studies|Postoperative Complications 136 KLF11 31124255 Pediatr Diabetes 2019 10.1111/pedi.12868 0 0 0 368 Humans|Child, Preschool|Child|Infant|Mason-Type Diabetes|Diabetes Mellitus, Type 2|Insulin|Diabetes Mellitus, Type 1|Islet Cell|Promoter Regions, Genetic|Repressor Proteins|Mutation|Cell Cycle Proteins|KLF11 protein, human 136 KLF11 30899365 Am J Transl Res 2019 PMC6413250 2 8 0 368 Humans|Y 27632|*rho-Associated Kinases|*Cells, Epithelial|Tight Junction|Nasal Epithelium|*Pyridines|*Amides|Cells, Cultured|Gap Junctions|Claudin-4|DFNA3 protein, human|Connexins|Cell Communication|Downregulation|Upregulation|*Progenitor Cells|Claudin-1|TERT protein, human 136 KLF11 30897781 Molecules 2019 PMC6471463 10.3390/molecules24061105 0 4 0 368 Animals|*Flavonoids|*Antidepressive Agents|fenugreek seed meal|Plant Extracts|Depression|Fenugreek|Serotonin|Behavior, Animal|Phytotherapy|Corticosterone|Hippocampus|Monoamine Oxidase|Dopamine|Motor Activity 136 KLF11 30819249 Vet. Res. 2019 PMC6394056 10.1186/s13567-019-0634-2 0 17 0 368 Swine|Animals|*Circovirus|*Spleen|Circoviridae Infections|Swine Diseases|CXCL13 protein, human|*Chemokine CXCL13|Viral Load|Sequencing, RNA|Antibodies, Viral|Transcriptome Profiling|DNA, Viral|Gene Ontology|*Apoptosis|Lymphocytes 136 KLF11 30790652 Gene 2019 10.1016/j.gene.2019.02.034 0 4 0 368 *Osteogenesis|*Cell Differentiation|Jeune syndrome|Ellis-Van Creveld Syndrome|*Downregulation|Mesenchymal Stem Cells|Short Rib-Polydactyly Syndrome|Hedgehog Proteins|Cilia|Cells, Cultured|Mutation 136 KLF11 30602303 Arterioscler. Thromb. Vasc. Biol. 2019 PMC6393209 10.1161/ATVBAHA.118.311612 3 2 0 368 Mice|Humans|Animals|*Thromboplastin|*Factor XI|Endothelial Cells|Smooth Muscle Cells|Muscle, Smooth, Vascular|Mice, Knockout|*Thrombosis|RNA, Small Interfering|RNA Interference|Kruppel-Like Transcription Factors|Aortas|Promoter Regions, Genetic|Cells, Cultured|ferric chloride|Chlorides|Ferric Compounds|KLF11 protein, human|Repressor Proteins 136 KLF14 31675530 Placenta 2019 10.1016/j.placenta.2019.09.013 1 0 0 13 Female|Pregnancy|Mice|Animals|*Transcription Factor|*Placentas|Genomic Imprinting|DNA Methylation|Insulin-Like Growth Factor II|Gene Expression Regulation, Developmental|Fetal Growth|*Complement Factor B|Allele|Klf14 protein, mouse|Kruppel-Like Transcription Factors 86 KLF14 31648151 Forensic Sci Int Genet 2019 10.1016/j.fsigen.2019.102189 0 1 0 13 *DNA Methylation|Reproducibility of Results|CpG Islands|Forensic Genetics|*DNA|LIM-Homeodomain Proteins|Genetic Markers|Sp Transcription Factors|PCR|Muscle Proteins|Acetyltransferases|Transcription Factors|cytidylyl-3'-5'-guanosine|Dinucleoside Phosphates|High-Throughput Nucleotide Sequencing 86 KLF14 31589552 Metab Syndr Relat Disord 2019 10.1089/met.2019.0070 0 0 0 13 86 KLF14 31518965 Atherosclerosis 2019 10.1016/j.atherosclerosis.2019.08.012 0 2 0 13 *Lipoprotein Lipase|*Down-Regulation|*Atherosclerosis|Apolipoproteins E|Lipid Metabolism|Macrophages|MicroRNAs|Cytokines|Inflammation|*Complement Factor B 86 KLF14 30745849 Int. J. Biol. Sci. 2019 PMC6367579 10.7150/ijbs.30652 4 1 0 13 Humans|*Glycolysis|*Transcription Factor|*Colorectal Cancer|HCT116 Cells|*Downregulation|Prognosis|Carcinogenesis|*Colonic Neoplasms|Biomarkers, Tumor|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Kruppel-Like Transcription Factors|Disease-Free Survival|Disease Progression|KLF14 protein, human|Sp Transcription Factors 86 KLF16 31007729 Exp Ther Med 2019 PMC6468394 10.3892/etm.2019.7349 0 0 0 93 *Transcriptome|Gene Regulatory Networks|Gene Expression Profiling|Transcription Factors|Oligonucleotide Array Sequence Analysis|Protein Interaction Maps|*Osteoporosis|Databases, Genetic 26 KLF16 30915712 Mol. Neurobiol. 2019 PMC6728282 10.1007/s12035-019-1566-6 0 4 0 93 Animals|Mice|DRD1 protein, human|*Dopamine D1 Receptor|Corpus Striatum|Cocaine|Dopamine Uptake Inhibitors|Receptors, Dopamine D2|Dopamine|Neurons|Signal Transduction|Klf16 protein, mouse|Kruppel-Like Transcription Factors|Disc1 protein, mouse|Nerve Tissue Proteins 26 KLF8 31827393 Cancer Cell Int. 2019 PMC6862788 10.1186/s12935-019-1016-6 1 5 0 370 *RNA, Long Noncoding|*Tongue Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Carcinoma, Squamous Cell|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms 102 KLF8 31624471 Cancer Cell Int. 2019 PMC6781403 10.1186/s12935-019-0970-3 0 6 0 370 Humans|Carcinoma, Non-Small-Cell Lung|*Lung Cancer|RNA Interference|Repressor Proteins|Cell Proliferation|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|KLF8 protein, human 102 KLF8 31499743 Math Biosci Eng 2019 10.3934/mbe.2019294 0 1 0 370 Humans|*Embryonic Stem Cell|*Cell Differentiation|Human Embryonic Stem Cells|CDH1 protein, human|E-Cadherin|Transcription Factors|*B-Lymphocytes|Repressor Proteins|Zinc Finger|Antigens, CD|Promoter Regions, Genetic|*Mathematical Model|KLF8 protein, human 102 KLF8 31364106 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201907_18418 1 2 0 370 *miRNA|*Osteosarcoma|*Cell Proliferation|*Apoptosis|*Upregulation|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|RNA, Long Noncoding|Cell Line, Tumor|Cell Movement|3' Untranslated Regions|Prognosis 102 KLF8 31124603 J. Cell. Mol. Med. 2019 PMC6653475 10.1111/jcmm.14378 3 5 0 370 Humans|*Stomach Neoplasms|*Glycolysis|Gene Expression Regulation, Neoplastic|Immunohistochemistry|Repressor Proteins|Biomarkers, Tumor|*Glucose Transporter Type 4|Liver Neoplasms|Cell Line, Tumor|Neoplasm Staging|Cell Transformation, Neoplastic|KLF8 protein, human 102 KLF8 31045845 Medicine (Baltimore) 2019 PMC6504245 10.1097/MD.0000000000015519 0 0 0 370 Humans|*Factor VIII|*Prognosis|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Carcinomas|RNA, Long Noncoding|Repressor Proteins|KLF8 protein, human 102 KLF8 30972179 Am J Transl Res 2019 PMC6456509 0 3 0 370 Humans|*Factor VIII|*Nedd4 Ubiquitin Protein Ligases|Ubiquitylation|E3 Ubiquitin Ligase|Endosomal Sorting Complexes Required for Transport|Posttranslational Modification|Phosphorylation|Cell Nucleus|Downregulation|Co-Immunoprecipitation|HEK293 Cells|KLF8 protein, human|Repressor Proteins 102 KLK10 31796117 J Transl Med 2019 PMC6891961 10.1186/s12967-019-02151-8 0 0 0 169 *Precision Medicine|RNA, Long Noncoding|MicroRNAs|Gene Expression Regulation, Neoplastic|RNA, Messenger|Gene Regulatory Networks|Prognosis|Biomarkers, Tumor|Gene Expression Profiling|Colorectal Cancer|Kaplan-Meier Estimate|Colonic Neoplasms|*Genetic Research 148 KLK10 31612115 Front Oncol 2019 PMC6776930 10.3389/fonc.2019.00996 3 0 0 169 148 KLK10 31467673 Transl Neurodegener 2019 PMC6712703 10.1186/s40035-019-0168-6 1 14 0 169 Humans|*Alzheimer Disease|*Fluorodeoxyglucose F18|Amyloid beta-Peptides|tau Proteins|*Positron-Emission Tomography|Peptide Fragments|KLK6 protein, human|*Kallikrein|Biomarkers|Phosphorylation|KLK10 protein, human 148 KLK10 31119602 Front Med 2019 10.1007/s11684-018-0643-y 0 4 0 169 *Iodine Radioisotopes|*PC-3 Cells|*Gene Therapy|*Brachytherapy|Cell Line, Tumor|Adenoviridae|Symporters|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Transfection|Xenograft Model Antitumor Assays|Cell Proliferation 148 KLK10 31117946 BMC Mol Cell Biol 2019 PMC6532135 10.1186/s12860-019-0192-5 4 1 0 169 *Lamin Type A|emerin|*Nuclear Proteins|*Membrane Proteins|*Cell Nucleus|Lamin B|Nuclear Envelope|Muscular Dystrophy, Emery-Dreifuss|Cytoskeleton|Actin|Interphase|Chromatin 148 KLK10 30643192 Oncogene 2019 10.1038/s41388-018-0660-y 10 3 0 169 Humans|*Prognosis|Prospective Studies|Neoplasm Recurrence, Local|*Cell Free DNA|DNA, Neoplasm|Biomarkers, Tumor|DNA Methylation|Epigenetic|Model, Logistic|Case-Control Studies|KLK10 protein, human|Kallikreins 148 KLK10 30614796 Cancer Biomark 2019 10.3233/CBM-181758 2 0 0 169 *Thyroid Cancer, Papillary|*Gene Expression Profiling|Thyroid Cancer|*Microarray Analysis|Gene Regulatory Networks|Transcriptome|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor 148 KLK15 31515705 Head Neck Pathol 2019 10.1007/s12105-019-01076-4 0 0 0 19 *Carcinoma, Adenoid Cystic|KLK15 protein, human|*Kallikrein B'|*Salivary Glands|trypsin-like serine protease|tripeptide aminopeptidase|*Aminopeptidases|Prognosis|Biomarkers, Tumor|*Polymerase Chain Reaction|RNA, Messenger 53 KLK4 31868942 Clin. Exp. Pharmacol. Physiol. 2019 10.1111/1440-1681.13235 0 0 0 334 Mice|Animals|*Squamous Cell Carcinoma|Mouth Neoplasms|Mice, Nude|Phosphatidylinositol 3-Kinases|*Apoptosis|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|RNA Interference|Head and Neck Neoplasms|kallikrein 4|Kallikreins|Downregulation|Signal Transduction 240 KLK4 31829025 Neoplasma 2019 10.4149/neo_2019_190306N191 0 6 0 334 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|Endothelial Cells|MicroRNAs|kallikrein 4|Kallikreins|*Neovascularization, Pathologic|Gene Expression Regulation, Neoplastic|shRNA|Cell Line, Tumor|Cell Proliferation|Cell Movement|Tumorigenesis|Wnt Signaling Pathway 240 KLK4 31446281 Neoplasia 2019 PMC6713813 10.1016/j.neo.2019.07.010 0 6 0 334 Humans|Male|*Pseudogenes|*Gene Fusion|*Prostate Cancer|kallikrein 4|Kallikreins|Proto-Oncogene Proteins c-ets|Oncogene Proteins, Fusion|SPINK1|Transcription Factors|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|SPINK1 protein, human 240 KLK4 31417410 Front Physiol 2019 PMC6682599 10.3389/fphys.2019.00925 2 1 0 334 Swine|Animals|*Amelogenin|*Proteome|*Phosphorylation|*Tooth Calcification|Amelogenesis|*Calcification, Physiologic|Matrix Metalloproteinase 20|Microscopy, Electron, Transmission|*Minerals|*Calcinosis|enamel matrix proteins|Dental Enamel Proteins 240 KLK4 31397325 Acta Crystallogr F Struct Biol Commun 2019 10.1107/S2053230X19009610 0 0 0 334 Humans|Male|kallikrein 4|*Serine Protease|*Kallikrein B'|Protein Binding|Binding Sites|Amino Acid Sequence|Substrate Specificity|Crystallography, X-Ray|Models, Molecular|Ligands|Prostate Cancer 240 KLK4 31391482 Sci Rep 2019 PMC6686015 10.1038/s41598-019-47615-5 1 0 0 334 Humans|*Serine Protease Inhibitors, Kazal Type|*Proteases|Serine Proteinase Inhibitors|Cystine Knot Motifs|Amino Acid Sequence|Protein Engineering|Serine Endopeptidases|Disulfides 240 KLK4 31265790 Biochem. Cell Biol. 2019 10.1139/bcb-2019-0017 1 4 0 334 Humans|Mice|Animals|*Squamous Cell Carcinoma|Mouth Neoplasms|Mice, Nude|Epithelial-Mesenchymal Transition|kallikrein 4|Kallikreins|MicroRNAs|Cell Movement|CDH1 protein, human|N-Cadherin|Gene Expression Regulation, Neoplastic|Prognosis|Cell Line, Tumor|Cell Proliferation|Matrix Metalloproteinase 2|Matrix Metalloproteinase 9|Biomarkers, Tumor|Antigens, CD 240 KLK4 31058493 Biochemistry 2019 10.1021/acs.biochem.9b00191 0 0 0 334 Humans|Trypsin Inhibitors|kallikrein 4|Kallikreins|*Peptides|Hydrogen Bonding|Sunflower|SERPINI2 protein, human|Serpins|Serine Proteinase Inhibitors|matriptase|Protein Binding|Trypsin|Peptides, Cyclic|Active Site|Serine Protease|Molecular Dynamics Simulation|Cyclization|Neoplasm Proteins 240 KLK4 31007611 Cancer Cell Int. 2019 PMC6458728 10.1186/s12935-019-0799-9 1 16 0 334 *RNA, Long Noncoding|*Stomach Neoplasms|*Wnt Signaling Pathway|*Cell Migration|*Downregulation|*Neovascularization, Pathologic|beta Catenin|*Catenins|Cell Proliferation|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|*Neoplastic Processes|Apoptosis|*Transcription Factors|*Morphogenesis 240 KLK4 30945557 Artif Cells Nanomed Biotechnol 2019 10.1080/21691401.2019.1593999 10 3 0 334 Humans|Female|*RNA, Circular|*Cell Proliferation|MIRN637 microRNA, human|MicroRNAs|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Carcinogenesis|Signal Transduction 240 KLK4 30929801 J Oral Biosci 2019 10.1016/j.job.2018.12.002 1 5 0 334 *Ameloblasts|Amelogenesis|Matrix Metalloproteinase 20|Amelogenin|*Isoforms|Transforming Growth Factor beta1|Kallikreins 240 KLK4 30838594 Methods Mol. Biol. 2019 10.1007/978-1-4939-9012-2_36 0 0 0 334 Humans|Amelogenesis Imperfecta|Tooth Abnormalities|Mutations|Phenotype|Tooth Diseases|Craniofacial Abnormalities|Boston|CNNM4 protein, human|Cation Transport Proteins|FAM20A protein, human|Dental Enamel Proteins|ROGDI protein, human|Membrane Proteins|Nuclear Proteins 240 KLK4 30811511 PLoS ONE 2019 PMC6392272 10.1371/journal.pone.0212968 2 3 0 334 Female|Humans|*Ovarian Cancer|*Cystadenocarcinoma, Serous|kallikrein 4|*Kallikrein|Carcinoma, Ovarian Epithelial|mRNA|Gene Expression Regulation, Neoplastic|Progression-Free Survival|Real-Time Polymerase Chain Reaction 240 KLK4 30644845 Acta Crystallogr D Struct Biol 2019 PMC6333282 10.1107/S2059798318016492 0 2 0 334 Cattle|Animals|*Trypsin|*Kallikrein|*Bauhinia|recombinant Kunitz protease inhibitor|Recombinant Proteins|Aprotinin|Amino Acid Sequence|Plant Proteins|Binding Sites 240 KLK4 30613336 ACS Med Chem Lett 2019 PMC6295872 10.1021/acsmedchemlett.8b00422 4 1 0 334 Humans|Male|trypsin inhibitor MCoTI-II|kallikrein 4|*Kallikrein B'|*Cyclotides|*Peptides, Cyclic|Prostate Cancer|Cell Line, Tumor|Disease Progression 240 KLK6 31866765 Cancer Cell Int. 2019 PMC6916460 10.1186/s12935-019-1056-y 0 0 0 379 *Urinary Bladder Neoplasms|*Prognosis|*Transcriptome|Neoplasm Invasiveness|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease Progression|Muscle 265 KLK6 31734318 Exp. Neurol. 2019 10.1016/j.expneurol.2019.113115 0 6 0 379 Humans|Mice|Animals|*Alzheimer Disease|Mice, Transgenic|Amyloid beta-Peptides|Amyloid beta-Protein Precursor|*Neuroplasticity|*Disease Models, Animal|tau Proteins|Hippocampus|EPHB2 protein, human|Receptor, EphB2|Memory, Spatial|Brain|*Inhibition, Psychological|Neurons|Kallikreins|KLK6 protein, human 265 KLK6 31692974 Oncotarget 2019 PMC6817440 10.18632/oncotarget.27153 2 2 0 379 Humans|Caco-2 Cells|KLK6 protein, human|*Kallikrein B'|*Cell Transformation, Neoplastic|*Tumorigenesis|Colonic Neoplasms|tripeptide aminopeptidase|Colorectal Cancer|*Aminopeptidases|*Colon|mRNA|Adenocarcinoma|Gene Expression Regulation, Neoplastic|MicroRNAs|endopeptidase B|*Cysteine Endopeptidases|Disease-Free Survival|Cell Line, Tumor 265 KLK6 31682009 J. Periodontol. 2019 10.1002/JPER.19-0467 0 0 0 379 Humans|*Smokers|*Transcriptome Analysis|Cotinine|Smoking|*Mucosa|*Immunity, Innate|*Gene Expression 265 KLK6 31675166 ChemMedChem 2019 PMC7004151 10.1002/cmdc.201900536 1 0 0 379 Humans|Female|*Oxazolidinones|KLK6 protein, human|*Kallikrein B'|*Structure-Activity Relationships|Ovarian Neoplasms|HCT 116 Cells 265 KLK6 31467673 Transl Neurodegener 2019 PMC6712703 10.1186/s40035-019-0168-6 1 14 0 379 Humans|*Alzheimer Disease|*Fluorodeoxyglucose F18|Amyloid beta-Peptides|tau Proteins|*Positron-Emission Tomography|Peptide Fragments|KLK6 protein, human|*Kallikrein|Biomarkers|Phosphorylation|KLK10 protein, human 265 KLK6 31370719 Integr Cancer Ther 2019 PMC6681251 10.1177/1534735419864434 0 1 0 379 265 KLK6 31279501 J. Dermatol. Sci. 2019 10.1016/j.jdermsci.2019.06.007 1 1 0 379 *Kallikrein|Netherton Syndrome|*Epidermis|Serine Peptidase Inhibitor Kazal-Type 5|Skin|*Epidermal Cells|Keratinocytes|Proteinase Inhibitory Proteins, Secretory|Atopic Dermatitis|Psoriasis|Proteolysis|Upregulation 265 KLK6 31276031 BMJ Open Ophthalmol 2019 PMC6579564 10.1136/bmjophth-2018-000254 0 0 0 379 Humans|*Stevens-Johnson Syndrome|Conjunctival Diseases|Conjunctiva|*Epithelium 265 KLK6 31255470 J. Dermatol. Sci. 2019 10.1016/j.jdermsci.2019.06.004 0 0 0 379 *Netherton Syndrome|Serine Peptidase Inhibitor Kazal-Type 5|Epidermis|Skin|Epidermal Cells|Kallikreins|*Endopeptidases 265 KLK6 31081307 Minerva Med. 2019 10.23736/S0026-4806.19.06086-5 1 0 0 379 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|CA-125 Antigen|Adnexal Diseases|BRCA1 protein, human|BRCA1 Protein|Tumor Markers|Ovary|Ultrasonography|KLK6 protein, human|Kallikreins 265 KLK6 31045568 Acta Crystallogr F Struct Biol Commun 2019 10.1107/S2053230X19003169 0 0 0 379 *Netherton Syndrome|Kallikreins|Protease Inhibitors|Protein Binding|Amino Acid Sequence|X Ray Crystallographies 265 KLK6 30980596 Mol Oncol 2019 PMC6822253 10.1002/1878-0261.12493 1 3 0 379 Humans|Mice|Animals|KLK6 protein, human|*Kallikrein B'|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Endopeptidases|Cell Movement|Downregulation|S100 Proteins|Transfections|S100A14 protein, human|Calcium-Binding Proteins|S100A16 protein, human 265 KLK6 30758105 Pathol. Int. 2019 PMC6850125 10.1111/pin.12771 0 1 0 379 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Macrophages|Carcinoma, Squamous Cell|Tumor Microenvironment|Cell Line, Tumor|Neovascularization, Pathologic|Disease Progression 265 KLLN 31602202 Exp Ther Med 2019 PMC6777329 10.3892/etm.2019.7936 4 1 0 121 Animals|Rats|*Hypoxia-Ischemia, Brain|MicroRNAs|Apoptosis|Cell Proliferation|In Situ Nick-End Labeling|Signal Transduction|Brain|MIRN204 microRNA, rat 31 KLLN 31382188 Mol Ther Nucleic Acids 2019 PMC6676247 10.1016/j.omtn.2019.06.003 1 9 0 121 *Nonsmall Cell Lung Cancer|*Tumor Suppressor Protein p53|Lung Neoplasms|*Genes, Tumor Suppressor|MicroRNAs|*Signal Transduction|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|CDH1 protein, human|N-Cadherin|Cell Movement|Cell Proliferation|Downregulation|Cell Line, Tumor|Long Non-Coding RNA|Vimentin|Antigens, CD 31 KLLN 31312371 Am J Transl Res 2019 PMC6614641 1 2 0 121 Animals|Rabbits|MicroRNAs|Downregulation|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Genes, Tumor Suppressor|Cell Movement|Up-Regulation|killin protein, human|Tumor Suppressor Proteins|Cell Line, Tumor|Viability, Cell|Myocytes, Smooth Muscle|*Coronary Heart Disease 31 KLLN 31269460 Biochim Biophys Acta Gene Regul Mech 2019 10.1016/j.bbagrm.2019.06.005 0 3 0 121 *Vemurafenib|*Melanoma|RNA Stability|3' Untranslated Regions|RNA-Binding Proteins|Trans-Activators|RNA, Messenger|Cell Line, Tumor|Mutation 31 KLLN 31062505 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61166 1 0 0 121 Humans|*Hamartoma Syndrome, Multiple|PTEN protein, human|*PTEN Phosphohydrolase|BMPR1A protein, human|*Bone Morphogenetic Protein Receptors, Type I|Juvenile polyposis syndrome|Neoplastic Syndromes, Hereditary|Intestinal Polyposis|*Mutation|Germ-Line Mutation|Phenotype|Genotype|Heterozygote|Intellectual Disability 31 KLLN 30921768 Endocr. Relat. Cancer 2019 10.1530/ERC-18-0485 1 7 0 121 Male|Female|*Carcinoma, Intraductal, Noninfiltrating|*DNA Methylation|*Promoter Regions, Genetic|Genes, BRCA2|H-cadherin|Cadherins|Genes, p16|Genes, Regulator 31 KLLN 30728494 Nat. Immunol. 2019 10.1038/s41590-019-0327-z 0 0 0 121 *Autoimmune Disease|Language 31 KLLN 30710169 Virchows Arch. 2019 10.1007/s00428-018-02516-2 2 0 0 121 Humans|Female|*Endometrial Carcinoma|Carcinoma, Endometrioid|Cystadenocarcinoma, Serous|Adenocarcinoma, Clear Cell|SMARCA4 protein, human|Nuclear Proteins|Transcription Factors|Mutation|PTEN protein, human|PTEN Phosphohydrolase|DNA Mutational Analysis|Genes, Regulator|ARID1A protein, human|Immunohistochemistry|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Microsatellite Instability|Oncogenes 31 KLLN 30664260 Exp. Dermatol. 2019 10.1111/exd.13888 4 2 0 121 *Keratinocytes|*Cell Proliferation|*Psoriasis|*Cell Differentiation|MicroRNAs|Skin|Down-Regulation|Up-Regulation|Transcriptional Activation|Cell Line 31 KLRC4 31502863 J. Comput. Biol. 2019 10.1089/cmb.2019.0180 0 0 0 16 *Computational Biology|Gene Regulatory Networks|RNA, Micro|Messenger RNA|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|*Biomarkers|*Myocardial Infarction|Gene Expression|Transcription Factors 24 KYNU 31825151 Proteomics 2019 10.1002/pmic.201900250 0 0 0 204 Pregnancy|Humans|Female|*Proteomics|*Embryo Implantation|*Endometrium|*Fertility|Fertilization in Vitro|Embryo, Mammalian|Embryonic Development|Cells, Epithelial|Trophoblast|Cell Line 68 KYNU 31732530 J. Immunol. 2019 PMC6904439 10.4049/jimmunol.1900069 2 1 0 204 Mice|Animals|*Neutralizing Antibody|*HIV-1|kynureninase|*HIV Antibodies|*Hydrolases|*B Cells|HIV Envelope Protein gp41|*Cross Reactions|HIV Infections|Immune Tolerance|Antibodies, Monoclonal|*HIV Seropositivity|Autoantigens 68 KYNU 31622668 Ann. 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Dermatol. 2019 10.1111/ced.14072 1 7 0 204 *Carcinoma, Squamous Cell|*Down-Regulation|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|kynureninase|*Skin Neoplasms|*Hydrolases|Neoplasm Invasiveness|Cell Movement|Signal Transduction|Cell Proliferation|*Transcription Factors|Cell Line, Tumor 68 KYNU 31332944 J. Cell. Mol. Med. 2019 PMC6787497 10.1111/jcmm.14547 2 1 0 204 Humans|Female|Mice|Animals|kynureninase|*SCID Mice|*NOD Mice|*Hydrolases|Receptor, ErbB-2|Immunohistochemistry|Cell Proliferation 68 KYNU 31320639 Nat Commun 2019 PMC6639385 10.1038/s41467-019-11177-x 1 0 0 204 Humans|*Epigenome|CpG Islands|Epigenetic|DNA Methylation|Epigenesis, Genetic|Genome-Wide Association Study|Quantitative Trait Loci|*Biomarkers|Genome, Human 68 KYNU 31177094 J. Biol. Chem. 2019 PMC6635453 10.1074/jbc.AC119.009475 1 0 0 204 Animals|coenzyme Q10|rhodoquinone|*Ubiquinone|*Kynurenine|Caenorhabditis elegans|Rhodospirillum rubrum|Escherichia coli|Oxidation-Reduction 68 KYNU 30871024 Int J Mol Sci 2019 PMC6429050 10.3390/ijms20051241 1 21 0 204 Humans|*Monocytes|*Proteome|NF-kappa B|I-kappa B Proteins|Tumor Necrosis Factor-alpha|Signal Transduction|NF-KappaB Inhibitor alpha|Phosphorylation|Inflammation 68 KYNU 30718454 Transl Psychiatry 2019 PMC6361928 10.1038/s41398-018-0360-y 5 0 0 204 Genome-Wide Association Study|*Gene-Environment Interaction|*Depression|United Kingdom|*Biological Specimen Banks|Multifactorial Inheritance|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Depressive Disorder, Major|Scotland|Risk Factors|Stress, Psychological 68 KYNU 30665415 BMC Syst Biol 2019 PMC6341689 10.1186/s12918-019-0680-4 6 4 0 204 *miRNAs|*Parkinson Disease|Neurodegenerative Diseases|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|*Biomarkers|Gene Ontology|Computational Biology|Protein Interaction Maps|RNA, Messenger|*Early Diagnosis 68 LACRT 31009613 Exp. Eye Res. 2019 PMC6570564 10.1016/j.exer.2019.04.022 1 0 0 69 Humans|Mice|Animals|*Lacrimal Apparatus|*C57BL Mouse|*Keratitis, Herpetic|Herpes Simplex Virus 1|Cornea|CD4-Positive T-Lymphocytes|*Disease Models, Animal|Lymphocyte Activation|Corneal Stroma|Inflammation|*Dacryocystitis|Tears|Herpes Simplex 27 LAD1 31565785 Folia Morphol. (Warsz) 2019 10.5603/FM.a2019.0107 0 0 0 596 Male|Humans|Aged, 80 and over|*Coronary Vessels|*Autopsy|*Myocardium|Coronary Vessel Anomalies|Ventricular Septum 84 LAD1 31200085 Gene 2019 10.1016/j.gene.2019.06.016 0 0 0 596 Humans|*Chromatin|*Gene Therapy|Leukocyte adhesion deficiency type 1|Leukocyte-Adhesion Deficiency Syndrome|Lentivirus|Genetic Vectors|Transduction, Genetic|*Gene Expression|CD18 Antigens|Promoter Regions, Genetic|Chromosomal Proteins, Non-Histone|Heterogeneous-Nuclear Ribonucleoprotein Group A-B|CBX3 protein, human 84 LAD1 31123145 Proc. Natl. Acad. Sci. 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Dermatol. Sci. 2019 10.1016/j.jdermsci.2019.11.012 0 2 0 91 Humans|*Transcriptome|*Skin|*Myeloid Cells|Dendritic Cells|Gene Expression Profiling|Flow Cytometry 124 LAMP3 31827378 Mediators Inflamm. 2019 PMC6885256 10.1155/2019/7190596 0 1 0 91 Dendritic Cells|Gastric Mucosa|Antigens, CD|Membrane Glycoproteins 124 LAMP3 31683440 Chemosphere 2019 10.1016/j.chemosphere.2019.125127 0 4 0 91 Particulate Matter|Air Pollutants|Mitochondria 124 LAMP3 31675496 Cell 2019 10.1016/j.cell.2019.10.003 15 0 0 91 *Carcinoma, Hepatocellular|*Liver Neoplasms|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|Dendritic Cells|PTPRC protein, human|Leukocyte Common Antigens|Transcriptomes 124 LAMP3 31634533 J. 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Cell 2019 PMC6437130 10.1007/s13577-019-00236-6 0 0 0 91 Animals|Mice|*Organoids|*ICR Mice|*Pulmonary Alveoli|*Epithelium|matrigel|Laminin|pulmonary surfactant apoprotein|Pulmonary Surfactant-Associated Proteins|*Lung|Collagen|Proteoglycans|Cells, Squamous Epithelial|Cells, Cultured|*Tooth Socket|Cell Differentiation|Apoproteins|FGF7 protein, human|Fibroblast Growth Factor 7 124 laptm5 31701625 Mol Oncol 2019 PMC6944115 10.1002/1878-0261.12595 0 3 0 113 Ribosomal Protein S6 Kinases, 90-kDa|*Gliomas|Signal Transduction|Extracellular Signal Regulated Kinases|Amino Acid Sequence|Cells, Cultured|Sequence Homology, Amino Acid 49 laptm5 31545469 Mol Med Rep 2019 PMC6797998 10.3892/mmr.2019.10688 0 4 0 113 RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|TNFSF11 protein, human|*RANKL Protein|Osteoblasts|Osteoclasts|Osteogenesis|Cell Differentiation|*Cell Movement|Coculture|Gene Expression Regulation|Promoter Regions, Genetic|*Protein Transport|Downregulation 49 laptm5 32274467 Brain Commun 2019 PMC7145452 10.1093/braincomms/fcz022 0 0 0 113 Humans|Mice|Animals|*Alzheimer Disease|*Amyloid beta-Peptides|Genome-Wide Association Study|Plaque, Amyloid|Transgenic Mouse|Amyloid beta-Protein Precursor|Microglia|Amyloid|Disease Models, Animal|Membrane Glycoproteins|Amyloidosis 49 LARP6 31046834 Breast Cancer Res. 2019 PMC6498606 10.1186/s13058-019-1142-z 1 4 0 495 Humans|Pregnancy|Female|Child|*Receptor, Collagen|*Pregnancy-Associated Plasma Protein-A|*Parity|*Protein A|Discoidin Domain Receptor 2|*Disease Susceptibility|Cell Movement|Cell Line, Tumor|Signal Transduction|Cell Proliferation|Collagen|Postpartum|DDR2 protein, human 35 LARP6 30901265 Assay Drug Dev Technol 2019 10.1089/adt.2018.904 0 2 0 495 Humans|*Two-Hybrid System Techniques|Ribonucleoproteins|Type I Collagen|mRNA|Autoantigens|Protein Binding|Collagen|SL RNA|Fibrosis 35 LARP6 30674965 Sci Rep 2019 PMC6344531 10.1038/s41598-018-36841-y 2 1 0 495 Humans|Animals|Ribonucleoproteins|Type I Collagen|mRNA|Autoantigens|Hepatic Stellate Cells|Protein Binding|Fibrosis|Liver Cirrhosis|SL RNA|Liver|HEK293 Cells 35 LBX2 31796831 Sci Rep 2019 PMC6890746 10.1038/s41598-019-54845-0 0 0 0 16 Humans|*RNA, Long Noncoding|*Transcriptome|*Hemangioma, Cavernous, Central Nervous System|*Transcriptome Profiling|RNA, Messenger|Sequencing, Next-Generation|Signal Transduction 34 LBX2 31673844 Gastric Cancer 2019 10.1007/s10120-019-01019-6 1 1 0 16 *Stomach Neoplasms|Long Non-Coding RNA|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Cell Movement|Up-Regulation|Disease Progression 34 LBX2 31539129 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201909_18851 0 5 0 16 Humans|*Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|*Cell Proliferation|*Signal Transduction|A549 Cells|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Neoplastic Processes|Prognosis 34 LBX2 31512745 J. 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Commun. 2019 10.1016/j.bbrc.2019.02.079 6 11 0 16 *Esophageal Squamous Cell Carcinoma|*Heterogeneous Nuclear Ribonucleoprotein C|*mRNA|*Esophageal Neoplasms|Zinc Finger E-box-Binding Homeobox 1|Long Non-Coding RNA|Epithelial-Mesenchymal Transition|Cell Migration|Neoplasm Invasiveness|MicroRNAs|Gene Expression Regulation, Neoplastic|RNA, Anti-Sense|Disease Progression|Cell Line, Tumor|Cell Proliferation|Upregulation 34 LBX2 30613154 Onco Targets Ther 2019 PMC6306053 10.2147/OTT.S171957 5 0 0 16 *Glioblastoma|*Long Non-Coding RNA|*Prognosis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Proportional Hazards Model|Kaplan-Meier Estimate|Biomarkers, Tumor 34 LECT2 31480179 Asian-australas. J. Anim. Sci. 2019 PMC6819688 10.5713/ajas.19.0192 0 0 0 150 Animals|TLR3 protein, human|*Toll-Like Receptor 3|*Chickens|*Gene Expression Regulation|*Chemotactic Factors|*CD8 Antigens|Gene Expression Profiling|Gene Expression|Leukocytes|Amino Acid Sequence 152 LECT2 31474362 Cell 2019 10.1016/j.cell.2019.07.021 3 0 0 150 Humans|Mice|Animals|*Liver|Endothelial Cell|Signal Transduction|Receptor, TIE-2|Fibrosis, Liver|Upregulation|shRNA|Sinusoid|*Ligands|LECT2 protein, human|Intercellular Signaling Peptides and Proteins|Lect2 protein, mouse 152 LECT2 31453723 Appl Physiol Nutr Metab 2019 10.1139/apnm-2018-0818 2 0 0 150 Humans|Male|Insulin|Glucagon|fibroblast growth factor 21|Fibroblast Growth Factors|Insulin Resistance|Exercise|Blood Glucose|Nonesterified Fatty Acids|Follistatin|Glucose|Energy Expenditure|Exercise Test|LECT2 protein, human|Intercellular Signaling Peptides and Proteins 152 LECT2 31405664 Diabetes Metab Syndr 2019 10.1016/j.dsx.2019.06.027 1 0 0 150 *Metabolic Syndrome|Insulin Resistance|Obesity|fibroblast growth factor 21|Fibroblast Growth Factors|Selenoprotein P|Diabetes Mellitus, Type 2|Angiopoietin-like Proteins|Liver|Dyslipidemia 152 LECT2 31366824 Endocr. 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Appl. Genet. 2019 10.1007/s13353-019-00483-1 1 0 0 295 Horses|Animals|*Exome|*Genomics|Breeding|Frequencies, Allele|*Whole Exome Sequencing|SNPs|Genotype|Linkage Disequilibrium|Phenotype|Oligonucleotide Array Sequence Analysis|Running 295 LHX1 30620636 Am. J. Physiol. Endocrinol. Metab. 2019 PMC6415717 10.1152/ajpendo.00235.2018 0 10 0 295 Mice|Animals|LHX1 protein, human|LIM-Homeodomain Proteins|*Transcription Factor|DNA-Binding Proteins|LIM Domain Proteins|*Gene Expression Regulation|Insulin-Secreting Cells|Chromatin Immunoprecipitation|Knockout Mouse|Protein Binding|mRNA|Cell Differentiation|*Homeostasis|Glucose|Ldb1 protein, mouse|Lhx1 protein, mouse 295 LHX1 30616715 Elife 2019 PMC6324879 10.7554/eLife.43186 5 5 0 295 Animals|Xenopus Proteins|Xenopus laevis|*Tubule, Kidney|*Biological Evolution|Enhancer Elements, Genetic|Transcription Factors|DNA-Binding Proteins|Embryo, Nonmammalian|Animals, Genetically Modified|Gene Expression Regulation, Developmental|Conserved Sequence|In Situ Hybridization|Regeneration 295 LIM2 31526959 Drug Alcohol Depend 2019 10.1016/j.drugalcdep.2019.06.033 0 0 0 80 *Naloxone|*Drug Overdose|Narcotic Antagonists|Opioid-Related Disorders|Analgesics, Opioid|Health Education|Emergency Medical Services|Massachusetts|3'-(1-butylphosphoryl)adenosine 116 LIM2 31488873 Oncogene 2019 10.1038/s41388-019-0914-3 0 1 0 80 Mice|Animals|Humans|Child|*Sarcoma, Ewing|Neoplasm Recurrence, Local|EWS-FLI fusion protein|RNA-Binding Protein EWS|Proto-Oncogene Protein c-fli-1|*Neuroectodermal Tumors, Primitive, Peripheral|Oncogene Proteins, Fusion|*Oncogene Fusion|Cell Line, Tumor|RNA Interference|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|Apoptosis|NIH 3T3 Cells|Signal Transduction|Downregulation|*Neoplastic Processes|*Relapse 116 LIM2 31273321 J. Hum. Genet. 2019 10.1038/s10038-019-0627-z 1 0 0 80 Humans|*Myopathy|LIM Domain Proteins|Muscle Proteins|Soleus Muscle|Intracellular Signaling Peptides and Proteins|Muscle Fibers, Skeletal|*Imaging, Magnetic Resonance|Pedigree|Genetic Testing|Mutation|Hemizygote|Mutation, Missense|FHL1 protein, human 116 LIM2 30714187 Lett. Appl. Microbiol. 2019 10.1111/lam.13124 1 0 0 80 *Lactobacillus fermentum|Clostridium difficile|Enterotoxins|Bacterial Toxins|Gene Expression Regulation, Bacterial|Virulence|Sensing, Quorum|Bacterial Proteins|Virulence Factors|Genes, Bacterial|Lactobacillus|Gastrointestinal Tract|*Antibodies, Bacterial 116 LIMA1 31832114 EPMA J 2019 PMC6882982 10.1007/s13167-019-00187-w 1 0 0 489 Humans|*Pituitary Neoplasms|*Proteomics|*Follicle Stimulating Hormone|*Prognosis|Adenoma 43 LIMA1 30659648 J. Oral Pathol. Med. 2019 10.1111/jop.12828 1 0 0 489 *Smoking Water Pipes|*Keratinocytes|Waterpipe Smoking|Oral Cancer|Smoking|Smoke|Tobacco Smoking 43 LINC00958 31855084 Hum Gene Ther Methods 2019 10.1089/hgtb.2019.115 0 0 0 0 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancers|*MAP Kinase Signaling System|*Cell Proliferation|Adenocarcinoma of Lung|Long Non-Coding RNA|Cell Movement|Cell Line, Tumor|Adenocarcinoma|RNA Interference|JNK Mitogen-Activated Protein Kinases|Signal Transduction|Oncogenesis|Cell Transformation, Neoplastic|Upregulation 21 LINC00958 31819474 Onco Targets Ther 2019 PMC6842770 10.2147/OTT.S216342 1 3 0 0 Humans|*Nasopharyngeal Carcinoma|RNA, Long Noncoding|*Upregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|Nasopharyngeal Neoplasms|*Transcriptional Activation|Cell Proliferation|Cell Line, Tumor|Carcinoma|Cell Movement|Apoptosis|Disease Progression|NUAK1 protein, human|Protein Kinases|Repressor Proteins|MIRN625 microRNA, human 21 LINC00958 31804973 Aging (Albany NY) 2019 PMC6932897 10.18632/aging.102436 0 18 0 0 *Nucleus Pulposus|*RNA, Long Noncoding|Disk Degeneration|MMP13 protein, human|Matrix Metalloproteinase 13|Cell Proliferation|Upregulation|SMAD3 protein, human|*Smad3 Protein|MicroRNAs|Downregulation|Aggrecan|Extracellular Matrix|Cells, Cultured 21 LINC00958 31752512 Hum Gene Ther Methods 2019 10.1089/hum.2019.115 0 3 0 0 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancers|*MAP Kinase Signaling System|*Cell Proliferation|Long Non-Coding RNA|Adenocarcinoma of Lung|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Oncogenes|Oncogenesis|Lung|Gene Expression Profiling|Upregulation 21 LINC00958 31691355 J. 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Biochem. 2019 10.1002/jcb.29472 0 7 0 0 Humans|Female|*Uterine Cervical Neoplasms|*Cell Proliferation|RNA, Long Noncoding|*Upregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Line, Tumor|Cell Transformation, Neoplastic|*Transcriptional Activation|Tumorigenesis|Disease Progression|MIRN625 microRNA, human 21 LINC00958 31442551 Life Sci. 2019 10.1016/j.lfs.2019.116782 0 4 0 0 *RNA, Long Noncoding|*Carcinoma, Squamous Cell|*Mouth Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Movement|RNA Interference|Apoptosis 21 LINC00958 31413594 Onco Targets Ther 2019 PMC6661987 10.2147/OTT.S208318 2 1 0 0 Humans|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Cell Line, Tumor|Cisplatin|Radiation Tolerance|Gene Expression Regulation, Neoplastic|Cell Proliferation|Long Non-Coding RNA|Drug Resistance, Neoplasm|Apoptosis|Gene Knockdown Techniques|Prognosis|Genes, myc 21 LINC00958 31338870 J. Cell. Biochem. 2019 PMC6771803 10.1002/jcb.29200 3 0 0 0 Humans|Female|*RNA, Long Noncoding|*miRNA|*mRNA|*Prognosis|*Endometrial Cancer|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Ontology|Transcriptome|Kaplan-Meier Estimate|microRNA761 microRNA, human 21 LINC00958 31169309 J. Cell. Physiol. 2019 10.1002/jcp.28902 6 0 0 0 Humans|Mice|Female|Animals|*RNA, Long Noncoding|*RNA, Micro|*Uterine Cervical Neoplasms|HeLa Cells|Mice, Nude|ribonucleotide reductase M2|*Ribonucleoside Diphosphate Reductase|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Downregulation|Cell Line, Tumor|Gene Expression Profiling|MIRN-5095 microRNA, human 21 LINC00958 31161900 Cancer Biol. Ther. 2019 PMC6741574 10.1080/15384047.2019.1617571 2 0 0 0 *Carcinoma, Squamous Cell|*Mouth Neoplasms|*Cell Proliferation|Long Non-Coding RNA|Head and Neck Neoplasms|MicroRNAs|Cell Movement|Squamous Cell Carcinoma of Head and Neck|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Prognosis|Pancreatic Cancer 21 LINC00958 30720167 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201901_16872 3 0 0 0 *RNA, Long Noncoding|*Stomach Neoplasms|*Prognosis|Lymphatic Metastasis|*Neoplastic Processes|Biomarkers, Tumor|Kaplan-Meier Estimate|Cell Proliferation|Cell Line, Tumor|Real-Time Polymerase Chain Reaction 21 LINC00958 30639194 Cancer Lett. 2019 10.1016/j.canlet.2018.12.017 17 3 0 0 Humans|*RNA, Long Noncoding|*Pancreatic Cancer|Epithelial-Mesenchymal Transition|MicroRNAs|*Cell Transformation, Neoplastic|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|*Downregulation|Cell Line, Tumor|Apoptosis|Disease Progression|PAX8 protein, human|PAX8 Transcription Factor 21 Lingo2 31562318 Nat Commun 2019 PMC6764942 10.1038/s41467-019-12315-1 1 7 0 36 Mice|Animals|*Colitis|TFF3 protein, human|Trefoil Factor-3|Dextran Sulfate|Goblet Cells|Colon|Intestinal Mucosa|Mucins|Disease Models, Animal|Wound Healing|Apoptosis|*Helminths|ErbB Receptors 31 Lingo2 31396155 Front Endocrinol (Lausanne) 2019 PMC6667636 10.3389/fendo.2019.00485 1 0 0 36 *Growth Hormone|In Vitro Oocyte Maturation Techniques|Oocytes|*Human Growth Hormone|Fertilization in Vitro|*Pituitary Hormones, Anterior|*Drug Hypersensitivity|Mitochondria 31 Lingo2 30696080 Int J Mol Sci 2019 PMC6387145 10.3390/ijms20030555 4 5 0 36 Humans|*Gastric Cancers|Hedgehog Proteins|Cancer Stem Cells|Epithelial-Mesenchymal Transition|CD44 protein, human|Hyaluronan Receptors|Cell Motility|Gene Expression Regulation, Neoplastic|Cadherins|Nanog Homeobox Protein|Vimentin|Cell Line, Tumor|Cell Proliferation|Biomarkers, Tumor|Spheroids, Cellular|Drug Resistance, Neoplasm|*Phenotype 31 LMTK2 31760099 Life Sci. 2019 10.1016/j.lfs.2019.117097 0 5 0 253 Humans|Male|*Prostate Cancer|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Proliferation|Cell Movement|Cell Line, Tumor|Signal Transduction|Down-Regulation|Apoptosis|*Genes, Tumor Suppressor|MIRN183 microRNA, human 47 LMTK2 31748522 Sci Rep 2019 PMC6868282 10.1038/s41598-019-53638-9 1 0 0 253 Animals|*Lewy Body Disease|*Alzheimer Disease|*Lemur|*TYK2 Kinase|*Neocortex|tau Proteins|Amyloid beta-Peptides|*Neuropathology|alpha-Synuclein|*Protein-Serine-Threonine Kinases|*Nervous System Diseases 47 LMTK2 31722791 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.11.002 0 6 0 253 Animals|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Glycogen Synthase Kinase 3|*Glucose|*Phosphorylation|*Lemur|*Oxygen|Response Element, Antioxidant|*Signal Transduction|*Neurons|*Serine Threonine Kinase|*GA-Binding Protein Transcription Factor|Neuroprotection|Reactive Oxygen Species|Apoptosis|*Protective Agents|Cell Survival|Cell Hypoxia 47 LMTK2 31722712 Mol. Cancer 2019 PMC6854648 10.1186/s12943-019-1081-4 2 5 0 253 *Stomach Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|Cell Line, Tumor|Cell Movement|Disease Progression|Tumorigenesis|RNAs, Circular 47 LMTK2 31395338 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.07.122 0 0 0 253 Humans|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Glycogen Synthase Kinase 3|*Lemur|*TYK2 Kinase|*Signal Transduction|WNT3 protein, human|*Wnt3 Protein|beta Catenin|*Catenins|Hep G2 Cells|Cell Line, Tumor|Cell Proliferation|Downregulation|Cell Movement|Up-Regulation 47 LMTK2 31206648 FEBS Lett. 2019 10.1002/1873-3468.13486 1 1 0 253 Humans|Filaments, Actin|Actin|Myosin Heavy Chains|Cytoskeleton|OPTN protein, human|Transcription Factor TFIIIA|Carrier Proteins|Endosomes|Protein Binding|Adaptor Proteins, Signal Transducing|*Cell Physiological Phenomena|*Biological Transport|*Biological Processes 47 LMTK2 31068217 Acta Neuropathol Commun 2019 PMC6505310 10.1186/s40478-019-0715-5 3 13 0 253 *Kinesin|*Axonal Transport|*Alzheimer Disease|CDK5 protein, human|*Cyclin-Dependent Kinase 5|kinesin light-chain proteins|Microtubule-Associated Proteins|Phosphorylation|Neurons|Adaptor Proteins, Signal Transducing|*Brain|Protein Binding 47 LMTK2 30988068 Biosci. Rep. 2019 PMC6527928 10.1042/BSR20190363 9 0 0 253 Humans|*Stomach Neoplasms|*Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor|Downregulation|Signal Transduction|circRNAs 47 LMTK2 30980866 Cancer Lett. 2019 10.1016/j.canlet.2019.04.011 1 16 0 253 Animals|*Lemur|*TYK2 Kinase|Glycogen Synthase Kinase 3|*Cell Proliferation|I-kappa B Proteins|Phosphorylation|I-kappa B Kinase|NF-KappaB Inhibitor alpha|NF-kappa B|*Colon Cancer|Signal Transduction|Transcription Factor RelA|Cyclin D1|Cell Line, Tumor|Membrane Proteins|Cell Nucleus 47 LMTK2 30761001 Front Pharmacol 2019 PMC6361741 10.3389/fphar.2019.00024 2 55 0 253 Animals|*TYK2 Kinase|*Lemur|*Serine Threonine Kinase|Membrane Proteins|Signal Transduction|Protein Transport|Apoptosis|Cytoplasm|Madagascar 47 LMTK2 30597196 Biochim Biophys Acta Mol Basis Dis 2019 10.1016/j.bbadis.2018.12.023 1 0 0 253 Serine Threonine Kinases|Membrane Proteins|Cell Signaling|Cell Proliferation|Apoptosis|Cell Line, Tumor|Cell Migration|Protein Transport|Neurons 47 LPHN2 31490055 J Psychiatry Neurosci 2019 PMC6919916 10.1503/jpn.180098 0 0 0 177 Humans|*Genome-Wide Association Study|African Americans|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Cocaine 29 LPHN2 31354733 Front Immunol 2019 PMC6637653 10.3389/fimmu.2019.01594 2 0 0 177 Male|Humans|*Hepatitis A Virus Cellular Receptor 2|LGALS9 protein, human|*Galectins|FLRT3 protein, human|Membrane Proteins|Signal Transduction|Killer Cells, Natural|Leukemia, Myeloid, Acute|T-Lymphocytes, Cytotoxic 29 LPHN2 31176715 Neurobiol. Dis. 2019 PMC6689430 10.1016/j.nbd.2019.104494 1 1 0 177 Humans|Male|Female|Mice|Animals|Rats|*Amfetamine|*Dopamine|alpha-latrotoxin receptor|*Rats, Sprague-Dawley|Reflex, Startle|*Mice, Knockout|Receptors, Peptide|SLC6A3 protein, human|Dopamine Transporter|*Receptors, G-Protein-Coupled|Attention Deficit-Hyperactivity Disorder|DRD1 protein, human|Dopamine D1 Receptor|Corpus Striatum|Dopamine and cAMP-Regulated Phosphoprotein 32|Vesicular Monoamine Transporter 2|DDC protein, human|Aromatic-L-Amino-Acid Decarboxylases 29 LPHN2 30924295 Mol Genet Genomic Med 2019 PMC6503016 10.1002/mgg3.635 1 2 0 177 Humans|Orofacial Cleft 1|*Cleft Lip|Malaysia|*Cleft Palate|*Brain|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pedigree|Alleles|*Families, Extended|European Continental Ancestry Group|Case-Control Studies|Palate 29 LPHN2 30919913 Int. J. Dev. Biol. 2019 10.1387/ijdb.180184kt 0 0 0 177 Animals|*Xenopus laevis|*Neural Crest|Xenopus Proteins|Ectoderm|*Cell Movement|*Cell Differentiation|Embryo, Nonmammalian|Body Patterning|Gene Expression Regulation, Developmental|Embryogenesis|*Organogenesis|Gene Knockdown Techniques 29 LPHN2 30915543 Mol. Genet. Genomics 2019 10.1007/s00438-019-01549-9 3 0 0 177 Humans|Female|Animals|Rats|olfactomedin|Phylogeny|*Polymorphism, Single Nucleotide|*Glycoproteins|*Extracellular Matrix Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Amino Acid Sequence|Eye Proteins|Cytoskeletal Proteins|Sequence Homology, Amino Acid 29 LRBA 31887391 J. Allergy Clin. Immunol. 2019 10.1016/j.jaci.2019.12.896 2 0 0 308 Humans|Immunologic Deficiency Syndromes|Common Variable Immunodeficiency|CTLA-4 Antigen|Hematopoietic Stem Cell Transplantation|Adaptor Proteins, Signal Transducing|LRBA protein, human 131 LRBA 31883622 Allergol Immunopathol (Madr) 2019 10.1016/j.aller.2019.07.011 0 0 0 308 Mice|Animals|*Lipopolysaccharides|Immunologic Deficiency Syndromes|Adaptor Proteins, Signal Transducing|Autophagy|Homozygote|Lysosomes|Mutations|Protein Transport|Lrba protein, mouse 131 LRBA 31876783 J. Pediatr. Hematol. Oncol. 2019 10.1097/MPH.0000000000001708 0 0 0 308 Humans|CTLA4 protein, human|Cytotoxic T-Lymphocyte Antigen 4|Autoimmunity|Common Variable Immunodeficiency|Immunologic Deficiency Syndromes|Abatacept|Adaptor Proteins, Signal Transducing|Mutations|*Lipopolysaccharides|*Intestinal Diseases|LRBA protein, human 131 LRBA 31874111 J. Clin. 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Physiol. 2019 PMC7052682 10.1152/ajplung.00331.2019 0 4 0 54 Humans|Large-Conductance Calcium-Activated Potassium Channels|Smooth Muscle Cells|Muscle, Smooth, Vascular|Ion Channel Gating|Membrane Potentials|Protein Subunits|Neoplasm Proteins|Calcium|HEK293 Cells|LRRC26 protein, human 29 LRRC26 31613648 Am. J. Respir. Crit. Care Med. 2019 PMC6999107 10.1164/rccm.201905-0990OC 3 1 0 54 29 LRRC26 31451634 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6744894 10.1073/pnas.1907065116 0 4 0 54 Animals|Mice|*Hair Cells, Auditory, Inner|Large-Conductance Calcium-Activated Potassium Channels|Ion Channel Gating|Membrane Potentials|Cochlea|Patch-Clamp Techniques|Synaptic Transmission|Calcium 29 LRRC26 31348683 FASEB J. 2019 10.1096/fj.201900701RR 0 1 0 54 Animals|Inner Hair Cells|Large-Conductance Calcium-Activated Potassium Channels|Ion Channel Gating|Membrane Potentials|Calcium 29 lrrc32 31879265 Semin. Cell Dev. Biol. 2019 10.1016/j.semcdb.2019.12.010 3 0 0 51 Humans|Adult|TGFB1 protein, human|*Transforming Growth Factor beta1|*Fibrosis|*Transforming Growth Factor|Extracellular Matrix|Signal Transduction 128 lrrc32 31812328 Allergol Immunopathol (Madr) 2019 10.1016/j.aller.2019.09.002 0 0 0 51 Humans|Child|*Asthma|*Chinese|Gene Frequency|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Immunoglobulin E|Promoter Regions, Genetic|Case-Control Studies|LRRC32 protein, human|Membrane Proteins 128 lrrc32 31781506 Front Oncol 2019 PMC6861210 10.3389/fonc.2019.01212 0 0 0 51 128 lrrc32 31600200 PLoS ONE 2019 PMC6786621 10.1371/journal.pone.0213482 2 1 0 51 Humans|Latent TGF-beta Binding Proteins|leucine-rich repeat proteins|*Leukemia, Myeloid, Acute|Transforming Growth Factor beta1|Cells, Cultured|Intercellular Signaling Peptides and Proteins|Binding Proteins|Cell Proliferation|mRNA|LRRC32 protein, human|Membrane Proteins 128 lrrc32 31357555 Int J Mol Sci 2019 PMC6695992 10.3390/ijms20153676 1 0 0 51 Humans|*Glioblastoma|*Tumor Microenvironment|T-Cells, Regulatory|Immune Tolerance|*Immunologic Factors|Melanoma, Cutaneous Malignant|Malignant Melanoma|Glycoprotein|Membrane Proteins|Skin Neoplasms 128 lrrc32 31249951 TH Open 2019 PMC6524883 10.1055/s-0038-1670630 0 0 0 51 Humans|Mice|Animals|*Thrombus|Platelets|Hemostasis|Platelet Adhesiveness|Megakaryocytes|Zebrafish|BAMBI protein, human|Membrane Proteins|*Thromboembolism|*Hematopoiesis|Erythroblasts|Cell Differentiation|Lineages, Cell|Genomics|DCBLD2 protein, human|COMMD7 protein, human|Adaptor Proteins, Signal Transducing|LRRC32 protein, human 128 lrrc32 31158401 J. 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Genet. 2019 PMC6777458 10.1038/s41431-019-0380-y 2 0 0 51 Mice|Humans|Animals|*Transforming Growth Factor beta Receptor|*Cleft Palate|TGFBR2 protein, human|*Receptor, Transforming Growth Factor-beta Type II|Palate|*Homozygote|Transforming Growth Factor beta|Protein-Serine-Threonine Kinases|Signal Transduction|*Genes, Regulator|Mice, Knockout|Gene Expression Regulation, Developmental|Embryo, Mammalian|*Codon, Nonsense|Cell Proliferation|LRRC32 protein, human|Membrane Proteins 128 lrrc32 30775441 Sci Adv 2019 PMC6365109 10.1126/sciadv.aav2309 7 19 0 51 Animals|*Neutrophils|*Atherosclerosis|*Inflammation|Plaque, Atherosclerotic|Disease Progression|Endotoxemia|Disease Models, Animal|Signal Transduction|Anti-Inflammatory Agents 128 lrrc32 30768357 Am. J. Physiol. Heart Circ. Physiol. 2019 10.1152/ajpheart.00797.2018 2 0 0 51 Humans|*Monocytes|*Cardiovascular Diseases|*HIV Infections|Antigens, Differentiation, Myelomonocytic|*Lymphocyte Activation|Viral Load|Antigens, CD|Lipopolysaccharide Receptors|Biomarkers|Receptors, Cell Surface|*Blood Coagulation|Inflammation|*Lipids|T-Lymphocytes|South Africa 128 lrrc32 30674536 Cancer Res. 2019 PMC6420855 10.1158/0008-5472.CAN-18-2623 2 2 0 51 *T-Lymphocytes, Regulatory|Cancer|*Colon|Forkhead Transcription Factors|Immune Tolerance|Transforming Growth Factor beta|Lymphocyte Activation|Inflammation|Membrane Proteins|Signal Transduction|Cell Proliferation 128 lrrc32 30624672 Hum. Mol. 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Monit. 2019 PMC6873638 10.12659/MSM.917142 1 0 0 121 Humans|*Carcinoma, Hepatocellular|*Computational Biology|*Liver Neoplasms|*Prognosis|Protein Interaction Maps|Gene Expression Profiling|Gene Regulatory Networks|Gene Expression Profiles|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Databases, Genetic|Cluster Analysis|Survival Analysis|Signal Transduction Pathways|Receiver Operating Characteristic|Receptor Protein-Tyrosine Kinases|PTK7 protein, human|Cell Adhesion Molecules 669 LTK 31663508 Elife 2019 PMC6821493 10.7554/eLife.45789 1 0 0 121 *T Cells|*Interleukin-2|TYRP1 protein, human|*Membrane Glycoproteins|Signal Transduction|CD28 Antigens|Lymphocyte Activation|*Antigen Presenting Cells|GRB2 Adaptor Protein|Phosphoproteins|Phosphorylation|Protein-Tyrosine Kinases 669 LTK 31516605 Oncol Lett 2019 PMC6732990 10.3892/ol.2019.10736 0 0 0 121 Humans|Female|*Carcinoma, Ovarian Epithelial|*Computational Biology|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|Prognosis|Gene Expression Regulation, Neoplastic|CTCFL protein, human|DNA-Binding Proteins|Cell Line, Tumor|*Upregulation|Biomarkers, Tumor|*Transcriptional Activation|Cell Proliferation|RNA, Messenger|Downregulation|Neoplasm Grading 669 LTK 31227593 J. Cell Biol. 2019 PMC6683734 10.1083/jcb.201903068 3 5 0 121 Humans|*Endoplasmic Reticulum|LTK protein, human|*Receptor Protein-Tyrosine Kinases|COP-Coated Vesicles|Golgi Apparatus|Signal Transduction|Protein Transport|Phosphorylation|Guanine Nucleotide Exchange Factors|Aryl Hydrocarbon Receptor Nuclear Translocator|Vesicular Transport Proteins|Proteostasis|Neoplasm Proteins|Antigens, Neoplasm|HeLa Cells|Protein Binding 669 LTK 30637979 Adv Healthc Mater 2019 10.1002/adhm.201801226 3 0 0 121 Mice|Animals|matrigel|*Laminin|*Proteoglycans|*Collagen|*Drug Combinations|Extracellular Matrix|Collagen Type I|Tissue Engineering|Cells, Cultured|Cell Differentiation|Neurons|*B Cells|*Electrophysiological Phenomena 669 Ly75 31817155 Cells 2019 PMC6953077 10.3390/cells8121566 0 0 0 198 Humans|*Neoadjuvant Therapy|Receptor, ErbB-2|Receptors, Estrogen|Cyclophosphamide|Doxorubicin|Paclitaxel|Chemotherapy, Adjuvant|Antineoplastic Combined Chemotherapy Protocols|Neoplasm Staging|Stromal Cell 29 LYAR 31810132 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109674 1 2 0 134 Humans|Male|*Prostate|*Saponins|China|*Prostate Cancer|*Melanthiaceae|Cell Proliferation|PC3 Cell Line|lncRNA|Cell Line, Tumor|Cell Movement|Gene Expression Regulation, Neoplastic|Apoptosis|MicroRNAs|Xenograft Model Antitumor Assays|*Liliaceae|Tibet|GINS2 protein, human|Chromosomal Proteins, Non-Histone 32 LYAR 31504794 Nucleic Acids Res. 2019 PMC6821171 10.1093/nar/gkz747 1 7 0 134 *DNA, Ribosomal|*RNA, Ribosomal|Nuclear Proteins|Transcription Factors|*Acetyltransferases|RNA Polymerase I|Histone H3|Chromatin|Acetylation|transcription factor UBF|Pol1 Transcription Initiation Complex Proteins|Chromosomal Proteins, Non-Histone|*Ribosomes|DNA-Binding Proteins|Transcription, Genetic|Promoter Regions, Genetic|DNA Methylation|Protein Binding 32 LYAR 31413131 J. Virol. 2019 PMC6803289 10.1128/JVI.00769-19 0 8 0 134 Humans|IRF3 protein, human|*Interferon Regulatory Factor-3|*beta Interferon|*Phosphorylation|Immunity, Innate|Virus Replication|Immune Evasion|Protein-Serine-Threonine Kinases|Host-Pathogen Interactions|Signal Transduction|Viral Proteins|NF-kappa B|Viruses|Virus Infection|HEK293 Cells|LYAR protein, human|DNA-Binding Proteins|Nuclear Proteins 32 LYAR 31300855 Anal Bioanal Chem 2019 10.1007/s00216-019-01987-9 0 0 0 134 Humans|*Surface Plasmon Resonance|Molecular Docking Simulation|Fetal Hemoglobin|gamma-Globins|*Thalassemia|beta-Thalassemia|Nuclear Proteins|DNA-Binding Proteins|Binding Sites|Transcription Factors|K562 Cells|Base Sequence|Cells, Erythroid|Polymorphism, Genetic|Repressor Proteins|Mutation|5' Untranslated Region|LYAR protein, human 32 LYAR 31076509 J. Biol. Chem. 2019 PMC6635442 10.1074/jbc.AC119.008378 1 0 0 134 Humans|Animals|Mice|*Ribosome|*Cell Nucleolus|RNA, Ribosomal|Ribosomal Proteins|RNA Precursors|RNA Processing, Post-Transcriptional|Ribonucleoproteins|*Mammals|Cell Nuclei|Eukaryotes|Lyar protein, mouse|DNA-Binding Proteins|Nuclear Proteins 32 LYAR 31001336 Int J Endocrinol 2019 PMC6437746 10.1155/2019/6212681 0 0 0 134 Humans|*Graves Ophthalmopathy|*DNA Methylation|Graves Disease|*Chinese|Case-Control Studies 32 LYL1 31332244 Sci Rep 2019 PMC6646380 10.1038/s41598-019-46853-x 0 5 0 118 Mice|Animals|*Oncogenes|Gene Expression Regulation, Leukemic|Leukemia, Myeloid|*Oncogenesis|LYL1 protein, human|Oncogene Proteins, Fusion|Tumor Suppressor Proteins|*Malignancies, Hematological|Cell Proliferation|Basic Helix-Loop-Helix Transcription Factors 92 LYL1 31300405 Blood 2019 10.1182/blood.2019896175 0 0 0 118 Mice|Animals|TAL1 protein, human|T-Cell Acute Lymphocytic Leukemia Protein 1|GATA1 protein, human|GATA1 Transcription Factor|Thrombopoiesis|Megakaryocytes|Basic Helix-Loop-Helix Transcription Factors|Blood Platelets|Proto-Oncogene Proteins|Mice, Knockout|Neoplasm Proteins 92 LYL1 30962294 J. Immunol. 2019 PMC6504590 10.4049/jimmunol.1801220 0 0 0 118 Mice|Animals|TAL1 protein, human|*Transcription Factor, TAL1|LYL1 protein, human|Basic Helix-Loop-Helix Transcription Factors|*Cell Differentiation|Neoplasm Proteins|Hematopoietic Stem Cells|Transcription Factor|Erythropoiesis|Thrombopoiesis|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 92 LYL1 30700838 Leukemia 2019 10.1038/s41375-018-0361-0 2 0 0 118 Mice|Animals|*Thymocytes|nuclear pore complex protein 98|*Transcription Factors|LYL1 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Nuclear Pore Complex Proteins|*Neoplasm Proteins|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Transcription Factor, TAL1|LIM Domain Proteins|*Genes, Homeobox|Homeodomain Proteins|Mice, Transgenic|*Oncogene Fusion|Gene Expression Regulation, Leukemic|Adaptor Proteins, Signal Transducing|Oncogenes|Proto-Oncogene Proteins 92 LYL1 32422006 Crit. Rev. Eukaryot. Gene Expr. 2019 10.1615/CritRevEukaryotGeneExpr.2019026820 0 0 0 118 *X-Linked Combined Immunodeficiency Diseases|*Mutagenesis, Insertional|*Oncogenes|*Retrovirus|LIM Domain Proteins|*Gene Therapy|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Transcription Factors|Thymocyte|Proto-Oncogene Proteins|*Oncogenesis|Adaptor Proteins, Signal Transducing|Metalloproteins|Basic Helix-Loop-Helix Transcription Factors|IL2 Receptor|*Immunologic Deficiency Syndromes 92 LYNX1 31333465 Front Pharmacol 2019 PMC6616073 10.3389/fphar.2019.00748 1 0 0 3 Humans|Animals|Receptors, Nicotinic Acetylcholine|Neurotoxins|GPI-Linked Proteins|Snake Venoms|SLURP1 protein, human|Antigens, Ly|Urokinase-Type Plasminogen Activator 78 LYNX1 31332003 Proc. Natl. Acad. Sci. U.S.A. 2019 10.1073/pnas.1820847116 2 0 0 3 Humans|Mice|Animals|*Deep Learning|Rett Syndrome|Methyl-CpG-Binding Protein 2|*Disease Models, Animal|Autism|*Arousal|Neurodevelopmental Disorders|Cholinergic Agents 78 LYNX1 31150435 PLoS ONE 2019 PMC6544245 10.1371/journal.pone.0217339 2 7 0 3 Animals|Humans|*Receptors, Nicotinic Acetylcholine|*Water|*Lung Cancer|*Apoptosis|*Cell Cycle Arrest|A549 Cells|alpha7 Nicotinic Acetylcholine Receptor|Lung Adenocarcinoma|Cell Proliferation|Nicotine|GPI-Linked Proteins|Cells, Epithelial|Cell Line, Tumor|Signal Transduction|Keratinocytes|Protein Binding|LYNX1 protein, human 78 LYNX1 31114495 Front Pharmacol 2019 PMC6502960 10.3389/fphar.2019.00343 1 0 0 3 Animals|*Nicotinic Acetylcholine Receptor|*Neurotoxins|*Lynx|GPI-Linked Proteins|Acetylcholine|*Cell Membrane|*Mammals|Protein Binding|Cholinergic Neuron|Brain|*Biological Processes 78 LYNX1 31068932 Front Immunol 2019 PMC6491625 10.3389/fimmu.2019.00819 1 0 0 3 *Cancer|Antigens, Ly|*Histocompatibility Antigens|Lymphocytes 78 MACROD2 31698100 Eur J Med Genet 2019 10.1016/j.ejmg.2019.103805 0 0 0 58 Humans|Male|Adult|*Syndrome|Ectrodactyly|*Limb Deformities, Congenital|Split hand foot deformity|Hand Deformities, Congenital|Foot Deformities, Congenital|Phenotype|Abnormalities, Multiple|Mutations|Comparative Genomic Hybridization|Transcription Factors|Genetic Heterogeneity|Exons|Regulatory Sequences, Nucleic Acid 79 MACROD2 31681417 Front Genet 2019 PMC6804435 10.3389/fgene.2019.00970 2 0 0 58 Humans|*RNA, Long Noncoding|Genome-Wide Association Study|Autism Spectrum Disorder|Genetic Predisposition to Disease|Genetic Loci|Case-Control Studies|Mutations 79 MACROD2 31599159 ACS Chem. Biol. 2019 10.1021/acschembio.9b00429 2 1 0 58 *ADP-Ribose|*NAD|Poly Adenosine Diphosphate Ribose|*Catalysis|N-Glycosyl Hydrolases|Glycoside Hydrolases|Hydrolysis|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1 79 MACROD2 31480266 Animals (Basel) 2019 PMC6769677 10.3390/ani9090636 1 0 0 58 Cattle|Animals|*Genome-Wide Association Study|*Quantitative Trait Loci|*Tuberculosis, Bovine|Chromosome Mapping|Breeding|Polymorphism, Single Nucleotide|Genotype|Genomics|Gene Annotations|Case-Control Studies 79 MACROD2 31467233 Cancer Genomics Proteomics 2019 PMC6727074 10.21873/cgp.20144 2 1 0 58 *Transcriptome|*Whole Exome Sequencing|*Histiocytoma, Malignant Fibrous|Sarcoma|Soft Tissue Neoplasms|Gene Fusion|Repressor Proteins|Biomarkers, Tumor|In Situ Hybridization, Fluorescence|Genetic Predisposition to Disease 79 MACROD2 31379025 Clin. Exp. Allergy 2019 10.1111/cea.13476 1 0 0 58 *Asthma|*Smoking|Genome-Wide Association Study|*Tobacco Smoking|Polymorphism, Single Nucleotide|Genotype|Risk Factor 79 MACROD2 31216043 Nucleic Acids Res. 2019 PMC6582358 10.1093/nar/gkz305 12 0 0 58 Humans|*RNA|*Ribosylations, ADP|ADP-Ribose|ADP Ribosyltransferase|Poly(ADP-ribose) Polymerases|DNA Repair|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Nicotinamide Adenine Dinucleotide|Protein Processing, Post-Translational|Hydrolases|Signal Transduction|DNA|Chromatin Assembly and Disassembly|PARP10 protein, human|Proto-Oncogene Proteins 79 MACROD2 31055587 Cytogenet. Genome Res. 2019 10.1159/000499886 1 0 0 58 Humans|*Microcephaly|*Intellectual Disability|Comparative Genomic Hybridization|Abnormalities, Multiple|Chromosome Deletion|*Phenotypes|*Polydactyly|In Situ Hybridization, Fluorescence|Syndrome|Oligonucleotide Array Sequence Analysis|*Kidney|MACROD2 protein, human|Hydrolases|DNA Repair Enzymes 79 MACROD2 31004082 Sci Rep 2019 PMC6474865 10.1038/s41598-019-42654-4 5 0 0 58 Infant|Humans|Child|Infant, Newborn|*Preterm Infants|*Epigenome|Infant, Very Low Birth Weight|Infant, Premature, Diseases|Developmental Disabilities|Infant Behavior|DNA Methylation|Intensive Care Units, Neonatal|Neurologic Examination|Cohort Studies|Brain 79 MACROD2 30619475 Front Genet 2019 PMC6305994 10.3389/fgene.2018.00654 1 0 0 58 Humans|Mice|Animals|Child|*DNA Damage|ADP-ribosylarginine hydrolase|*N-Glycosyl Hydrolases|Adenosine Diphosphate Ribose|ADP Ribosylation|Hydrolases|DNA Repair|Protein Modification, Post Translational|*Biochemical Phenomena|MACROD2 protein, human|DNA Repair Enzymes 79 MACROD2 30610940 Prog. Neuropsychopharmacol. Biol. Psychiatry 2019 10.1016/j.pnpbp.2018.12.016 1 0 0 58 Humans|*Genome-Wide Association Study|*Autistic Disorder|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Allele|Linkage Disequilibrium|Haplotypes|Nerve Tissue Proteins|AS3MT protein, human|Methyltransferases|CUEDC2 protein, human|Carrier Proteins|Membrane Proteins 79 MAGEC1 31469419 Int. J. Cancer 2019 10.1002/ijc.32653 1 2 0 33 Humans|Female|*Carcinoma, Ovarian Epithelial|Genome-Wide Association Study|*Ovarian Neoplasms|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Case-Control Studies|African Americans 67 MAGEC1 30736848 J Immunother Cancer 2019 PMC6368815 10.1186/s40425-019-0520-5 4 0 0 33 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*mRNA|*Immunotherapy|Pemetrexed|*Immunotherapy, Active|Neoplasm Staging|Disease-Free Survival|*Cancer Vaccines|Antineoplastic Combined Chemotherapy Protocols|MUC1 protein, human|Mucin-1|*Adjuvants, Pharmaceutic|*Protamines 67 MAP3K10 31080060 Dev. Cell 2019 10.1016/j.devcel.2019.04.018 5 8 0 161 Humans|*Hyaluronic Acid|MARK2 protein, human|*Protein-Serine-Threonine Kinases|CD44 protein, human|Hyaluronan Receptors|Signal Transduction|Hyaluronidase|*Growth Inhibitors|Phosphorylation|Extracellular Matrix|Cell Movement|Cell Line, Tumor|Molecular Weight|*Ligands|Triple-Negative Breast Cancers|Cell Count|Hippo protein, human 61 MAP3K10 30853885 Front Mol Neurosci 2019 PMC6396726 10.3389/fnmol.2019.00019 3 13 0 161 Mice|Animals|*Neurocalcin|*Neurogenesis|Dentate Gyrus|Neurons|Hippocampus|Mice, Knockout|Mice, Inbred C57BL|Muscular Atrophy, Spinal 61 MAP6 31691285 J. Cell. Physiol. 2019 10.1002/jcp.29393 0 0 0 2068 Humans|*DNA Methylation|*Peripheral Nerve Injuries|Epigenesis, Genetic|Nerve Regeneration|Gene Ontology|Injury, Spinal Cord|Protein Interaction Maps|*Gene Expression Regulation|Spinal Cord|Gene Expression Profiling|Trauma, Nervous System|Central Nervous System|NUMBL protein, human|Intracellular Signaling Peptides and Proteins 78 MAP6 31348270 Medicine (Baltimore) 2019 PMC6708735 10.1097/MD.0000000000016534 0 0 0 2068 Humans|Male|*Lymphatic Metastasis|*Prostate Cancer|Nomogram|Prostatectomy|Lymph Node|Lymph Node Excision|Prostate-Specific Antigen|Area Under Curve|Predictive Value of Tests|Pelvis|Logistic Models|Retrospective Studies|Multivariate Analysis 78 MAP6 31289257 Aging (Albany NY) 2019 PMC6660046 10.18632/aging.102072 0 16 0 2068 Humans|Mice|Animals|*Parkinson Disease|*Glycosylation|1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|MPTP Poisoning|Dopamine|alpha-Synuclein|Mice, Inbred C57BL|Tyrosine Hydroxylase|Disease Models, Animal|1-nitrohydroxyphenyl-N-benzoylalanine|*Tyrosine|Neuroprotective Agents|*Benzamides|Microtubule-Associated Proteins 78 MAP6 31245373 Front Cell Dev Biol 2019 PMC6582194 10.3389/fcell.2019.00109 1 0 0 2068 *Golgi Apparatus|*Acylation|Protein Transport|Lipoylation|Acyltransferases|Membrane Proteins 78 MAP6 31116700 Biol. Chem. 2019 10.1515/hsz-2019-0149 2 0 0 2068 Animals|*Microtubule|Tubulin|tau Proteins|*Neurons|Cytoskeleton|Protein Binding|*Vertebrates 78 MAP6 30929793 Trends Cell Biol. 2019 PMC6527491 10.1016/j.tcb.2019.02.007 7 0 0 2068 *tau Proteins|Microtubules|Tubulin|Axons|Neurons 78 MAP9 31662330 Clin. Cancer Res. 2019 10.1158/1078-0432.CCR-19-1611 2 2 0 342 Humans|*Chromosomal Instability|*Colorectal Cancer|*Cell Transformation, Neoplastic|*Tumorigenesis|*Colonic Neoplasms|Spindle Apparatus|Signal Transduction|MAP9 protein, human|Microtubule-Associated Proteins 26 MAP9 31301305 Exp. Mol. Pathol. 2019 10.1016/j.yexmp.2019.104282 0 0 0 342 Humans|Female|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Osteoporosis, Postmenopausal|*Signal Transduction|MicroRNAs|Cell Proliferation|Apoptosis|Osteoblasts|Cell Survival|MAP9 protein, human|Microtubule-Associated Proteins 26 MAP9 31263577 Cell Death Discov 2019 PMC6591245 10.1038/s41420-019-0190-6 5 0 0 342 Humans|*RNA, Long Noncoding|*Focal Adhesion Protein-Tyrosine Kinases|*Prognosis|PTK2 protein, human|*Focal Adhesion Kinase 1|Receptor, ErbB-2|*Signal Transduction|Triple-Negative Breast Cancer|Biomarkers, Tumor 26 MATN2 31493245 Hum. Cell 2019 10.1007/s13577-019-00266-0 0 3 0 125 Humans|*Matrilin-2|*T-Lymphocytes, Regulatory|Leukocytes, Mononuclear|*Allergic Rhinitis|IL10 protein, human|Interleukin-10|Transforming Growth Factor beta|Nasal Mucosa|IL17A protein, human|Interleukin-17|MicroRNAs|Cell Differentiation|*Lymphocyte Activation|*Hematopoiesis|MATN2 protein, human|MIRN202 microRNA, human 55 MATN2 30624798 Biotechnol. Appl. Biochem. 2019 10.1002/bab.1726 0 1 0 125 *MAP Kinase Signaling System|*Matrilin Proteins|*Tumor Necrosis Factor-alpha|*Apoptosis|JNK Mitogen-Activated Protein Kinases|Hepatocytes|Cell Survival|Liver 55 MCM3AP 31886567 J. Cell. Biochem. 2019 10.1002/jcb.29580 0 0 0 190 Humans|Male|*Prognosis|RECQL protein, human|RecQ Helicases|Genetic Predisposition to Disease|*Prostate Cancer|Disease-Free Survival|Kaplan-Meier Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease Progression|Cohort Studies|China|Rad50 protein, human|DNA-Binding Proteins|DNA Repair Enzymes|PNPT1 protein, human|Exoribonucleases|SNRPB protein, human 67 MCM3AP 31836002 BMC Musculoskelet Disord 2019 PMC6911297 10.1186/s12891-019-2967-4 0 8 0 190 *RNA, Long Noncoding|*Chondrocytes|*HMGB1 Protein|*Lipopolysaccharides|MicroRNAs|Osteoarthritis|Liver Cancer|Cell Proliferation|RNA, Anti-Sense|Apoptosis|Signal Transduction|Cell Line, Tumor|*Cell Death 67 MCM3AP 31830901 Mol. Med. 2019 PMC6909501 10.1186/s10020-019-0121-2 0 4 0 190 *RNA, Long Noncoding|*Pancreatic Cancer|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|3' Untranslated Regions|RNA, Small Interfering|Apoptosis 67 MCM3AP 31761783 Aging (Albany NY) 2019 PMC6914412 10.18632/aging.102468 0 0 0 190 *RNA, Long Noncoding|*Carcinoma, Hepatocellular|*Liver Neoplasms|MicroRNAs|mRNA|Prognosis|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Ontology|*Disease Progression|Biomarkers, Tumor|Kaplan-Meier Estimate 67 MCM3AP 31759545 Taiwan J Obstet Gynecol 2019 10.1016/j.tjog.2019.09.024 0 0 0 190 Pregnancy|Female|Humans|Amniocentesis|*Congenital Heart Defects|Prenatal Diagnosis|Karyotyping|*Fetus|Comparative Genomic Hybridization|Ultrasonography, Prenatal 67 MCM3AP 31693222 J. Cell. Biochem. 2019 10.1002/jcb.29448 2 9 0 190 *RNA, Long Noncoding|*Disease Progression|MicroRNAs|Gene Expression Regulation, Neoplastic|*Lung Cancer|Cell Proliferation|*Neovascularization, Pathologic|Cell Line, Tumor 67 MCM3AP 31478223 J. Cell. Biochem. 2019 10.1002/jcb.29321 1 0 0 190 Humans|*RNA, Long Noncoding|*Glioblastoma|*Prognosis|Brain Neoplasms|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|MicroRNAs|Gene Expression Profiling|RNA, Messenger|Gene Ontology|Transcription Factors|*Thromboplastin 67 MCM3AP 31241196 Muscle Nerve 2019 10.1002/mus.26622 1 1 0 190 *Paralyses, Familial Periodic|*Mutation|Hypokalemic Periodic Paralysis|Pedigree|*Muscular Dystrophies|Ion Channel|*RNA Transport|RNA, Messenger 67 MCM3AP 31237446 DNA Cell Biol. 2019 10.1089/dna.2019.4770 4 2 0 190 Humans|*RNA, Long Noncoding|Carcinoma, Hepatocellular|Liver Neoplasms|Endothelial Cells|Gene Expression Regulation, Neoplastic|MicroRNAs|HepG2 Cells|Cell Proliferation|Cell Line, Tumor|Oncogenesis|Upregulation|Apoptosis 67 MCM3AP 31030335 Endocrine 2019 10.1007/s12020-019-01939-4 6 6 0 190 *Thyroid Cancer, Papillary|*RNA, Long Noncoding|MicroRNAs|Gene Expression Regulation, Neoplastic|Thyroid Neoplasms|Cell Proliferation|*Osteonectin|Cell Movement|Cell Line, Tumor|Signal Transduction 67 MCM3AP 30810967 Breast Cancer 2019 10.1007/s12282-019-00956-5 0 0 0 190 Humans|Japan|*Prognosis|Genetic Predisposition to Disease|Gene Frequency|*Risk|Polymorphism, Single Nucleotide|Genotype|Alleles|Kaplan-Meier Estimate|Case-Control Studies|Nuclear Proteins|Germinal Center 67 MCM3AP 30782188 Mol. Cancer 2019 PMC6381672 10.1186/s12943-019-0957-7 37 11 0 190 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|*Hepatocyte Nuclear Factor 3-alpha|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Carcinogenesis|Cell Line, Tumor|Cell Movement|Disease Progression 67 MCM9 31509747 Cell Rep 2019 10.1016/j.celrep.2019.07.095 3 1 0 93 Humans|Mice|Animals|TP53 protein, human|*Tumor Suppressor Protein p53|*DNA Damage|DNA Repair|Minichromosome Maintenance Proteins|Homologous Recombination|DNA Replication|Cell Cycle Proteins|DNA-Binding Proteins|Recombinational DNA Repair|*Malignancies, Hematopoietic|Hematopoietic Stem Cell Transplantation|MCM8 protein, human|MCM9 protein, human|Mcm9 protein, mouse|Mcm8 protein, mouse 45 MCM9 31467087 Genes Dev. 2019 PMC6771392 10.1101/gad.329508.119 4 0 0 93 Mice|Animals|*Homologous Recombination|Minichromosome Maintenance Proteins|DNA Replication|DNA Breaks, Double-Stranded|Recombinational DNA Repair|DNA Repair|DNA Damage|DNA-Binding Proteins|Cell Cycle Proteins|Mcm9 protein, mouse|Mcm8 protein, mouse 45 MCM9 31243857 Hum. Mutat. 2019 10.1002/humu.23853 0 1 0 93 Humans|*Prevalence|NTHL1 protein, human|*Deoxyribonuclease (Pyrimidine Dimer)|Adenomatous Polyposis Coli|*Colorectal Neoplasms|Mutations, Germline|Mutations|*Colon|Alleles|Genetic Predisposition to Disease|Phenotype|Mutation Frequency|MSH3 protein, human|MutS Homolog 3 Protein|MCM9 protein, human|Minichromosome Maintenance Proteins|FOCAD protein, human|Tumor Suppressor Proteins 45 MCM9 31052337 Genes (Basel) 2019 PMC6563057 10.3390/genes10050331 0 2 0 93 MCM2-7 Complex|CDC45 protein, human|Cell Cycle Proteins|Replication Origin|Origin Recognition Complex|DNA Replication|Saccharomyces cerevisiae Proteins|Chromatin|Saccharomyces cerevisiae|*Post-Translational Modifications|Cell Nucleus|G1 Phase|DNA|MCM10 protein, S cerevisiae 45 MCM9 31042289 J. Clin. Endocrinol. Metab. 2019 PMC6563799 10.1210/jc.2019-00248 4 0 0 93 Humans|Female|*Menopause, Premature|*Primary Ovarian Insufficiency|*Exome|*Whole Exome Sequencing|Pedigree|*Cohort Studies|Genetic Predisposition to Disease|Chromosomal Abnormalities|Amenorrhea 45 MCM9 30743181 DNA Repair (Amst.) 2019 10.1016/j.dnarep.2019.02.003 4 0 0 93 Humans|Female|Minichromosome Maintenance Proteins|DNA Replication|Homologous Recombination|DNA Repair|DNA-Binding Proteins|Cell Cycle Proteins|Primary Ovarian Insufficiency|Menopause, Premature|Mutations|MCM8 protein, human 45 MCM9 30648820 Cancer Sci. 2019 PMC6398883 10.1111/cas.13941 4 16 0 93 Humans|olaparib|*Cisplatin|*Phthalazines|*Piperazines|Poly(ADP-ribose) Polymerase Inhibitors|DNA Repair|Recombination Repair, Homologous|Rad51 Recombinase|Homologous Recombination|DNA Damage|Cell Line, Tumor|Minichromosome Maintenance Proteins|DNA-Binding Proteins|MCM8 protein, human|MCM9 protein, human 45 MCTS1 30885232 Mol. Cancer 2019 PMC6421700 10.1186/s12943-019-0988-0 22 135 0 209 Humans|*Triple-Negative Breast Cancer|*Interleukin-6|Neoplasm Recurrence, Local|MCTS1 protein, human|*Cell Cycle Proteins|*Oncogene Proteins|*Signal Transduction|Cancer Stem Cells|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Movement|Cell Line, Tumor|Receptors, Interleukin-6|Apoptosis|Prognosis|*Disease Progression 66 megf10 31790847 Bone 2019 PMC7120871 10.1016/j.bone.2019.115175 0 1 0 113 Child|Humans|*Bone Density|Absorptiometry, Photon|Osteoporosis|Bone|*Hispanic|Lumbar Vertebrae 60 megf10 31267131 Hum. Mol. Genet. 2019 PMC6606856 10.1093/hmg/ddz064 1 1 0 113 Humans|Animals|Mice|*Serotonin Uptake Inhibitors|*Myopathy|Myoblasts|Sertraline|Escitalopram|Membrane Proteins|Muscle, Skeletal|Drosophila|Phenotype|Cellular Proliferation|Mutation|Signal Transduction|Megf10 protein, mouse 60 megf10 31129437 J Psychiatr Res 2019 10.1016/j.jpsychires.2019.05.018 2 4 0 113 Humans|Mice|Animals|*Stroke|Brain Ischemia|*Depression|*Biomarkers|miRNA|Circulating MicroRNA|Gene Expression Profiling|Downregulation|Bioinformatics|Upregulation|Signal Transduction|Mirn140 microRNA, human|MIRN140 microRNA, mouse 60 megf10 31034467 PLoS Genet. 2019 PMC6508745 10.1371/journal.pgen.1007989 0 0 0 113 Animals|*Chickens|Genome|Allele Frequency|Selection, Genetic|Sequence Alignment|Breeding|SNPs|Sequence Analysis, DNA|*Acclimatization 60 megf10 30802937 FEBS Lett. 2019 PMC6504253 10.1002/1873-3468.13348 0 0 0 113 Animals|Mice|*Muscle Development|*Gain of Function Mutation|Myopathy|Myoblasts|Drosophila|Mutations|Muscle, Skeletal|Membrane Proteins|Phenotype|Signal Transduction|Cell Proliferation|Megf10 protein, mouse|Draper protein, Drosophila 60 megf10 30674530 Cancer Res. 2019 PMC6397665 10.1158/0008-5472.CAN-18-1261 5 4 0 113 Medulloblastoma|Neuroectodermal Tumors, Primitive|Cerebellar Neoplasms|Brain Tumors 60 METRN 31875034 Sci Rep 2019 PMC6930248 10.1038/s41598-019-56417-8 0 0 0 47 MIRN1229 microRNA, human|*RNA, Circular|*Glioma|*RNA, Micro|Cell Proliferation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Brain Neoplasms|Cell Movement|*Disease Progression|MTOR protein, human|*TOR Serine-Threonine Kinases|Up-Regulation|Cell Line, Tumor|Gene Knockdown Techniques|siRNA 22 METRN 31859449 Mol Genet Genomic Med 2019 PMC7057108 10.1002/mgg3.1102 1 0 0 47 *Colorectal Cancer|Microsatellite Instability|Prognosis|Proto-Oncogene Proteins B-raf|Kaplan-Meier Estimate|Disease-Free Survival|Biomarkers, Tumor|Mutation|*Colonic Neoplasms 22 METRN 31335652 Pain 2019 PMC6687406 10.1097/j.pain.0000000000001569 1 0 0 47 Male|Rats|Mice|Animals|*Rats, Sprague-Dawley|*Constriction|Reproducibility of Results|Mechanical Allodynia|Pain, Neuropathic|Gabapentin|Cyclohexanecarboxylic Acids|Analgesics|Pain Threshold|gamma-Aminobutyric Acid|Amines|Pain Measurement|Disease Models, Animal 22 METRN 30893615 Cell Rep 2019 10.1016/j.celrep.2019.02.084 1 1 0 47 *Cancer|*Epigenome|*Promoter Regions, Genetic|CpG Islands|DNA Methylation|Epigenesis, Genetic|Epigenetic|DNA, Neoplasm|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|Gene Expression Profiling|Transcription Factors 22 METRNL 31815932 PLoS Negl Trop Dis 2019 PMC6922449 10.1371/journal.pntd.0007908 1 2 0 81 Mice|Animals|*Th2 Cells|Filarioidea|Filariasis|Mice, Inbred BALB C|*Helminth|Cytokines|T-Lymphocytes, Regulatory|B Cells|Spleen|Fgl2 protein, mouse|Fibrinogen 47 METRNL 31766048 Med. Sci. Monit. 2019 PMC6894365 10.12659/MSM.920222 1 0 0 81 Humans|*Insulin Resistance|Diabetes Mellitus, Type 2|Body Mass Index|Obesity|Blood Glucose|Insulin|Adipokines|Waist Circumference|Adipose Tissue, Visceral|Glucose 47 METRNL 31635130 Cells 2019 PMC6829873 10.3390/cells8101283 3 0 0 81 Humans|*Diabetes Mellitus, Type 2|*Obesity|Insulin Resistance|Adipokines|Body Mass Index|Blood Glucose|Fibronectins|Inflammation 47 METRNL 31608723 J. Matern. Fetal. Neonatal. Med. 2019 10.1080/14767058.2019.1676713 0 0 0 81 47 METRNL 31570005 Biotech Histochem 2019 10.1080/10520295.2019.1656344 0 0 0 81 *Adipokines|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|Immunohistochemistry|Biomarkers, Tumor|Hyperplasia|Diagnosis, Differential|Epithelium 47 METRNL 31470086 Clin. Immunol. 2019 10.1016/j.clim.2019.108253 0 0 0 81 Humans|*Arthritis, Psoriatic|*Synovium|Arthritis, Rheumatoid|*Cytokines|Fluid, Synovial|Osteoarthritis|*Fibroblasts|IL17A protein, human|IL-17A|Skin|Inflammation 47 METRNL 31195974 BMC Genomics 2019 PMC6567458 10.1186/s12864-019-5880-1 2 0 0 81 Swine|Animals|*Ryanodine Receptor Calcium Release Channel|*DNA Methylation|*B-DNA|*Epigenome|*Muscle, Skeletal|CpG Islands|Epigenesis, Genetic|Polymorphism, Single Nucleotide 47 METRNL 30928991 Med. Sci. Monit. 2019 PMC6454984 10.12659/MSM.915331 2 4 0 81 Humans|*Insulin Resistance|*Diabetes Mellitus, Type 2|Impaired Glucose Tolerance|Prediabetes|Blood Glucose|Glucose Tolerance Test|Insulin|Insulin-Secreting Cells|Glucose|Body Mass Index 47 METRNL 30825562 Diabetes Res. Clin. Pract. 2019 10.1016/j.diabres.2019.02.026 4 0 0 81 *Glucose Intolerance|*Atherosclerosis|Blood Glucose|Insulin Resistance|Vascular Cell Adhesion Molecule-1|Diabetes Mellitus, Type 2|Intercellular Adhesion Molecule-1|E-Selectin|Biomarkers|Interleukin-6 47 MFSD8 31860737 J. Vet. Intern. Med. 2019 PMC6979099 10.1111/jvim.15663 1 0 0 93 Male|Animals|Cats|Ceroid Lipofuscinosis, Neuronal, 7|*Neuronal Ceroid-Lipofuscinoses|*Felis|*Frameshift Mutation|Homozygote|Membrane Transport Proteins|Mutation|Imaging, Magnetic Resonance 51 MFSD8 31741823 JIMD Rep 2019 PMC6850977 10.1002/jmd2.12057 0 0 0 93 *Neuronal Ceroid-Lipofuscinoses|Membrane Proteins|Mutation 51 MFSD8 31726844 Cesk Patol 2019 0 0 0 93 Humans|Male|Child|Child, Preschool|*Neuronal Ceroid-Lipofuscinoses|Homozygote|Membrane Transport Proteins|Seizures|Mutation|Atrophy|*Heart 51 MFSD8 31721179 Clin. Genet. 2019 PMC7064892 10.1111/cge.13673 2 0 0 93 Humans|Child|Adult|Adolescent|MFSD8 protein, human|*Membrane Transport Proteins|Lipofuscinosis, Neuronal Ceroid|*Maculopathy|Homozygote|Sequencing, Whole Exome|Pedigree|Mutation|*Retinal Disease|Retina 51 MFSD8 31687336 Mol Genet Metab Rep 2019 PMC6819867 10.1016/j.ymgmr.2019.100521 0 0 0 93 Male|Dogs|Animals|Female|*Neuronal Ceroid-Lipofuscinoses|Homozygote|Pedigree|Dog Diseases|Breeding|Cerebellum|Membrane Proteins|Alleles 51 MFSD8 31597037 N. Engl. J. Med. 2019 PMC6961983 10.1056/NEJMoa1813279 15 0 0 93 Humans|*Rare Disease|Neuronal Ceroid-Lipofuscinoses|Oligonucleotides, Antisense|*Oligonucleotides|Membrane Transport Proteins|Electroencephalography|Mutation|Seizures 51 MFSD8 31216804 Zhonghua Er Ke Za Zhi 2019 10.3760/cma.j.issn.0578-1310.2019.06.011 1 0 0 93 51 MFSD8 31105743 Front Genet 2019 PMC6494930 10.3389/fgene.2019.00370 0 0 0 93 Humans|*Neuronal Ceroid-Lipofuscinoses|*Siblings|*Sequencing, Next-Generation|*Chinese|Mutations|MFSD8 protein, human|Membrane Transport Proteins|Pedigree|Membrane Proteins|Phenotypes|Seizures|Brain 51 MFSD8 31006324 Ophthalmic Genet. 2019 10.1080/13816810.2019.1592200 1 0 0 93 MFSD8 protein, human|*Membrane Transport Proteins|Cone Rod Dystrophies|*Mutations|DNA Mutational Analysis|Neuronal Ceroid-Lipofuscinoses|Pedigree|Whole Exome Sequencing|Electroretinography|Visual Acuity 51 MICAL2 31565549 PeerJ 2019 PMC6743450 10.7717/peerj.7456 3 0 0 153 *RNA, Long Noncoding|*Prognosis|miRNAs|*Laryngeal Neoplasms|mRNA|*Squamous Cell Carcinoma of Head and Neck|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Disease Progression|Head and Neck Neoplasms 22 MICAL2 31004710 Biochim Biophys Acta Mol Basis Dis 2019 10.1016/j.bbadis.2019.04.008 1 3 0 153 Humans|Rats|Animals|*Endothelial Cell|*Vascular Endothelial Growth Factor A|*Cell Movement|FLT1 protein, human|VEGFR-1|*Viability, Cell|Neovascularization, Pathologic|*Cancer|Neovascularization, Physiologic|Vascular Endothelial Growth Factor Receptor-2|Drugs, Anti-Angiogenic|Cell Proliferation|Signal Transduction|*Capillary Endothelium|Microfilament Proteins|F-Actin|Cells, Cultured|CCG 1423 22 MICAL2 30853343 Microvasc. Res. 2019 10.1016/j.mvr.2019.03.001 8 8 0 153 Mice|Animals|*Muscle, Smooth, Vascular|*MAP Kinase Signaling System|Smooth Muscle Cells|*MicroRNAs|*Signal Transduction|Pulmonary Artery|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|Cell Proliferation|Vascular Remodeling|Hypertension, Pulmonary|Familial Primary Pulmonary Hypertension|Hypoxia|Cell Movement|Cells, Cultured|Disease Models, Animal 22 MIDN 31588691 Ann Clin Transl Neurol 2019 PMC6856597 10.1002/acn3.50914 2 0 0 245 Humans|*Parkinson Disease|midnolin|Cohort Studies|*Risk Factors|*Nuclear Proteins|parkin protein|Ubiquitin-Protein Ligases|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genetic Testing|Japan 23 MIDN 31418107 J. Assist. Reprod. Genet. 2019 PMC6823329 10.1007/s10815-019-01547-1 1 0 0 245 Humans|Male|*Infertility, Male|Spermatogenesis|Chromosomes, Human, Y|Comparative Genomic Hybridization|Chromosome Deletion|DNA Copy Number Variations|*Chromosome Structures 23 MIDN 31400503 Int J Surg 2019 10.1016/j.ijsu.2019.07.038 1 0 0 245 Humans|*Cohort Studies|*Nephrectomy|Living Donors|Kidney Transplantation|Tissue and Organ Harvesting|Retroperitoneal Space|Laparoscopy|Kidney|*Surgical Wound|*Reconstructive Surgical Procedures|*Physical Examination 23 MIEN1 31581708 Cancers (Basel) 2019 PMC6826896 10.3390/cancers11101486 3 11 0 102 33 MIEN1 31552186 Front Oncol 2019 PMC6738349 10.3389/fonc.2019.00868 1 4 0 102 Humans|*Neoplastic Processes|Neoplasm Proteins|Intracellular Signaling Peptides and Proteins|PTK2 protein, human|Focal Adhesion Kinase 1|Cell Movement|Cell Line, Tumor|Phosphorylation|G-Actin|Actin Filament|Annexin A2|Post-Translational Modifications|Cell Membrane|MIEN1 protein, human 33 MIEN1 31186737 Oncol Lett 2019 PMC6507308 10.3892/ol.2019.10203 3 1 0 102 Humans|Young Adult|Child|*Down-Regulation|*Osteosarcoma|Bone Neoplasms|MicroRNAs|*Prognosis|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Proliferation|*Disease Progression|Cell Movement|3' Untranslated Regions|Cell Line, Tumor|Apoptosis|Tumorigenesis|MIRN136 microRNA, human 33 MIEN1 31037122 Theranostics 2019 PMC6485192 10.7150/thno.30353 0 0 0 102 Rats|Humans|Animals|Pheochromocytoma|Adrenal Gland Neoplasms|Tumor Cells, Cultured|PC12 Cells|*Biomarkers|Guanidines|*Antibodies 33 MIEN1 30799275 Stem Cell Reports 2019 PMC6411484 10.1016/j.stemcr.2019.01.019 1 3 0 102 Mice|Animals|*Cellular Reprogramming|*Oocytes|Nuclear Transfer Techniques|Cloning, Organism|Blastocyst|Embryonic Development|*Cryopreservation|Embryo, Mammalian|Apoptosis|Cell Nucleus|Reactive Oxygen Species|Cytoplasm|Melatonin|Pluripotent Stem Cells 33 MIPEP 31739726 Epigenetics 2019 PMC7188395 10.1080/15592294.2019.1695340 1 0 0 43 Middle Aged|Humans|Adult|*DNA Methylation|*African Americans|*Metabolic Syndrome|CpG Islands|Epigenetic|Epigenesis, Genetic|Genome-Wide Association Study|DNA|Risk Factors 29 MIPEP 31604699 Br J Ophthalmol 2019 10.1136/bjophthalmol-2019-314782 1 0 0 43 Humans|Genome-Wide Association Study|*Genotype-Phenotype Correlation|Asian|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Myopia|Genotype|Alleles|Eye|Genetic Variation|Biometry 29 MIPEP 31526596 Mol. Ther. 2019 PMC6822234 10.1016/j.ymthe.2019.09.001 8 0 0 43 *Cancers|*Non-Coding RNA|Long ncRNA|miRNA, Primary|peptide B|Gene Expression Regulation, Neoplastic|RNA, Circular|Peptides|Epithelial-Mesenchymal Transition|Biomarkers, Tumor|Disease Progression|Retinal Nonattachment, Nonsyndromic Congenital|*Retinal Diseases 29 MIPEP 31446369 Comput Biol Chem 2019 10.1016/j.compbiolchem.2019.107100 0 1 0 43 *Arachis|*miRNA|RNA, Plant|ESTs|Sequence Analysis, RNA|Gene Expression Regulation, Plant|Computational Biology|Conserved Sequence|*Fabaceae|*Peptides 29 MIPEP 31300455 Br J Ophthalmol 2019 10.1136/bjophthalmol-2019-314203 0 1 0 43 Humans|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Genome-Wide Association Study|Haplotypes|Alleles|Myopia, Degenerative 29 MIR135B 31044154 Mol Ther Oncolytics 2019 PMC6479751 10.1016/j.omto.2019.03.011 1 8 0 0 sulforafan|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Isothiocyanates|RNA, Micro|Gene Expression Regulation, Neoplastic|*Disease Progression|Cell Line, Tumor|Cell Proliferation 26 MIR17HG 31825998 PLoS ONE 2019 PMC6905564 10.1371/journal.pone.0226212 0 0 0 93 Humans|*Genes, Homeobox|Homeodomain Proteins|Transcription Factors|*Myeloid Cells|Gene Expression Regulation, Leukemic|Leukemia, Myeloid, Acute|Cell Differentiation|Hematopoiesis|Lymphopoiesis|Myelodysplastic Syndrome|Myelopoiesis|Hematopoietic Stem Cells|Cell Line, Tumor|Gene Expressions 62 MIR17HG 31802000 Nature 2019 PMC6908757 10.1038/s41586-019-1815-x 2 0 0 93 Humans|Child|Neoplasm Recurrence, Local|Ribonuclease III|Neoplasms, Germ Cell and Embryonal|DEAD-box RNA Helicases|MicroRNAs|Germ-Line Mutation|Mutation|Brain Neoplasms|*Relapse 62 MIR17HG 31706574 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.10.180 0 3 0 93 *Cisplatin|*Osteosarcoma|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|MicroRNAs|Sp1 protein, human|*Sp1 Transcription Factor|Cell Proliferation|Tumorigenesis|Cell Movement|Cell Line, Tumor|Up-Regulation|Apoptosis|Signal Transduction|Disease Progression 62 MIR17HG 31547203 Noncoding RNA 2019 PMC6958423 10.3390/ncrna5040048 2 0 0 93 Humans|*Long Non-Coding RNA|Toxoplasma|*Neuroglia|*Cells, Cultured|Retina 62 MIR17HG 31527075 Blood 2019 PMC6839951 10.1182/blood.2019002600 6 0 0 93 *In Situ Hybridization, Fluorescence|*Lymphoma, Large B-Cell, Diffuse|Proto-Oncogene Proteins c-bcl-6|Proto-Oncogene Proteins c-myc|Proto-Oncogene Proteins c-bcl-2|Translocation, Genetic|Gene Rearrangement|Prognosis|Antineoplastic Combined Chemotherapy Protocols|Germinal Center 62 MIR17HG 31511857 Biol. Reprod. 2019 PMC7016285 10.1093/biolre/ioz183 1 0 0 93 Humans|Female|Mice|Animals|*Estrogens|estrogen receptor alpha, human|Estrogen Receptor alpha|*Gene Expression Regulation|Oestradiol|Uterus|Progesterone|mRNA|Transcriptome|Ovariectomy|RNA, Long Noncoding|Signal Transduction 62 MIR17HG 31409641 Cancer Res. 2019 10.1158/0008-5472.CAN-18-3880 9 3 0 93 Humans|*RNA, Long Noncoding|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|MicroRNAs|*Disease Progression|HCT116 Cells|Tumorigenesis|Upregulation|Neoplasm Invasiveness|Cell Proliferation|Cell Line, Tumor|*Neoplastic Processes|Signal Transduction|*Colonic Neoplasms|Transcriptional Activation|MIRN17 microRNA, human 62 MIR17HG 31403267 Adv Clin Exp Med 2019 10.17219/acem/94392 1 0 0 93 *RNA, Long Noncoding|*Small Cell Lung Carcinoma|*Alternative Splicing|*Sequencing, RNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|MicroRNAs|Biomarkers, Tumor|Prognosis|Gene Expression Profiling|RNA, Messenger|*Whole Exome Sequencing|Lung Neoplasms 62 MIR17HG 31290724 Cell Cycle 2019 PMC6986557 10.1080/15384101.2019.1641388 0 4 0 93 *Sirtuin 1|*DNA Breaks, Double-Stranded|miRNAs|RNA, Long Noncoding|Cell Proliferation|Gene Expression Regulation|DNA Repair|DNA 62 MIR17HG 31266011 J Innate Immun 2019 PMC6959121 10.1159/000500419 2 5 0 93 Humans|Male|Female|*Secretory Leukoprotease Inhibitor|*Monocytes|*Downregulation|*Estrogens|miRNAs|Upregulation|Oestradiol|Transfection|Chromatin Immunoprecipitation|MIRN19 microRNA, human 62 MIR17HG 31191623 Front Genet 2019 PMC6549003 10.3389/fgene.2019.00525 0 12 0 93 Humans|Animals|*Up-Regulation|*Wnt Pathway|*Cell Proliferation|*Transcriptional Activation|beta Catenin|Lymphoid Enhancer-Binding Factor 1|*Catenins|MicroRNAs|Cell Line, Tumor|Cell Movement|Promoter Regions, Genetic|Chloride, Lithium|LEF1 protein, human|MIRN17 microRNA, human|MIRN17-92 microRNA, human 62 MIR17HG 31191202 Mol Syndromol 2019 PMC6528091 10.1159/000497402 1 0 0 93 Humans|13q deletion syndrome|*Chromosomes, Human, Pair 13|Chromosome Deletion|Chromosome Disorders|*Phenotype|Microcephaly|Comparative Genomic Hybridization|Genotype-Phenotype Correlation|Hypotonia|Abnormalities, Multiple|Abnormalities, Urogenital|Chromosome Banding|Haploinsufficiency|Brazil 62 MIR17HG 31186404 Cell Death Dis 2019 PMC6560107 10.1038/s41419-019-1685-z 1 7 0 93 IRF1 protein, human|*Interferon Regulatory Factor-1|*Stomach Neoplasms|miRNAs|Gene Expression Regulation, Neoplastic|*Catenins|Upregulation|Wnt Signaling Pathway|Cell Line, Tumor|Downregulation 62 MIR22HG 31819482 Onco Targets Ther 2019 PMC6875507 10.2147/OTT.S227541 0 1 0 85 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|Gene Expression Regulation, Neoplastic|MicroRNAs|*Real-Time Polymerase Chain Reaction|Cell Proliferation|Cell Transformation, Neoplastic|Cell Line, Tumor|RNA, Messenger 37 MIR22HG 31729379 Nat Commun 2019 PMC6858455 10.1038/s41467-019-13168-4 1 9 0 85 Humans|*Adenylosuccinate Lyase|*Triple-Negative Breast Cancer|*Prolyl Hydroxylase|*Procollagen-Proline Dioxygenase|*Oncogenes|*Oncogenesis|Cell Proliferation|Transcription Factors|Cell Line, Tumor|Transcriptional Activation|Upregulation 37 MIR22HG 31613058 J. Cell. Mol. Med. 2019 PMC6850943 10.1111/jcmm.14721 4 0 0 85 Humans|*RNA, Long Noncoding|*Prognosis|miRNA|mRNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Kaplan-Meier Analysis|Survival Analysis 37 MIR22HG 31579415 Oncol Lett 2019 PMC6757318 10.3892/ol.2019.10752 0 0 0 85 Humans|Male|*Prostate|Long Non-Coding RNA|miRNAs|*Prostate Cancer|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|RNA, Messenger|Biomarkers, Tumor|Transcriptome|Kaplan-Meier Estimate|TGFBR2 protein, human|TGFBR2|Adenocarcinoma 37 MIR22HG 31547203 Noncoding RNA 2019 PMC6958423 10.3390/ncrna5040048 2 0 0 85 Humans|*Long Non-Coding RNA|Toxoplasma|*Neuroglia|*Cells, Cultured|Retina 37 MIR22HG 31402962 Oncol Lett 2019 PMC6676736 10.3892/ol.2019.10605 1 0 0 85 MIRN149 microRNA, human|MicroRNAs|MIRN765 microRNA, human|MIRN650 microRNA, human|RNA, Long Noncoding|*Colorectal Cancer|Messenger RNA|Gene Regulatory Networks|Prognosis|*Colonic Neoplasms|Gene Ontology|Gene Expression Profiling|Transcriptome|Kaplan-Meier Estimate 37 MIR22HG 31298336 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201907_18327 1 3 0 85 *Carcinoma, Papillary|*Thyroid Gland|*Thyroid Cancer, Papillary|*Cell Proliferation|*Cell Cycle|MicroRNAs|Cell Movement|Thyroid Neoplasms|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|CDKN1B protein, human|*Cyclin-Dependent Kinase Inhibitor p27|Cell Line, Tumor|Down-Regulation|Apoptosis 37 MIR22HG 31291201 Aging (Albany NY) 2019 PMC6660029 10.18632/aging.102071 3 1 0 85 Humans|*RNA, Long Noncoding|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Movement|Esophageal Neoplasms|Apoptosis|Adenocarcinoma|Signal Transduction 37 MIR22HG 30856284 J Gene Med 2019 10.1002/jgm.3085 1 2 0 85 *RNA, Long Noncoding|*Cholangiocarcinoma|*Cell Proliferation|Bile Duct Neoplasms|*Wnt Signaling Pathway|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|*Catenins|MicroRNAs|Cell Line, Tumor|Apoptosis|Bile Ducts, Intrahepatic 37 Mkx 31692087 J. Orthop. Res. 2019 10.1002/jor.24513 1 0 0 126 Humans|Tenocytes|Achilles Tendon|Early Growth Response Protein 1|Gene Expression|Morphogenesis|Homeostasis 50 Mkx 31512449 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 10.7507/1002-1892.201902040 0 0 0 126 *Hamstring Tendons|*Correlation of Data|*Anterior Cruciate Ligament Reconstruction|Anterior Cruciate Ligament|Anterior Cruciate Ligament Injuries|*Hamstring Muscles|Autografts|Tendons|Arthroscopy|Transplantation, Autologous|Collagen 50 Mkx 31475745 Anim. Genet. 2019 10.1111/age.12844 0 0 0 126 Female|Humans|Pregnancy|Swine|Animals|Infant, Newborn|Quantitative Trait Loci|*Phenotype|*Mammary Glands, Animal|Genome-Wide Association Study|Breeding|Sus scrofa|Crosses, Genetic|SNPs|*Birth|*Chinese|X Chromosome|SPRED2 protein, human|Repressor Proteins 50 Mkx 31277043 Stem Cell Res 2019 PMC7082636 10.1016/j.scr.2019.101489 4 4 0 126 Horses|Animals|*Tenocytes|*Induced Pluripotent Stem Cells|Bone Marrow Mesenchymal Stem Cells|Tendons|*Gene Expression|Cell Differentiation|Gene Expression Regulation|Cells, Cultured|EGR1 protein, human|Early Growth Response Protein 1 50 Mkx 31115927 J. Orthop. Res. 2019 10.1002/jor.24352 1 6 0 126 Humans|*Tenocytes|*Vitamin D|*Cellular Proliferation|VDR protein, human|Vitamin D Receptor|Dexamethasone|Glucocorticoids|Tendon|Collagen Type I|Cell Differentiation|*Vitamins|Cells, Cultured|*Hyperplasia|Basic Helix-Loop-Helix Transcription Factors|Gene Expression|*Cholestanes|Extracellular Signal Regulated Kinases|RNA, Messenger 50 MLLT11 31671695 Cells 2019 PMC6912824 10.3390/cells8111357 0 2 0 143 Humans|*Prognosis|Retrospective Studies|*Esophageal Cancer|Esophagectomy|*Signal Transduction|*Oncogene|CD44 protein, human|Hyaluronan Receptors|Carcinoma, Squamous Cell|Neoplasm Recurrence, Local|Biomarkers, Tumor|Neoplasm Proteins|Cell Movement|Cell Line, Tumor 40 MLLT11 31587870 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.10.001 0 0 0 143 *Burkitt Lymphoma|*Cannabidiol|Neoplasm Proteins|Cell Line, Tumor|Proto-Oncogene Proteins|*Immunotherapy|Oncogenes|*Immunologic Factors 40 MLLT11 31297450 J Cancer Metastasis Treat 2019 PMC6623974 10.20517/2394-4722.2018.84 1 8 0 143 *T-Lymphocytes|Cell Line, Tumor|Neoplasm Proteins|Cell Movement|Proto-Oncogene Proteins|Cell Proliferation|*Cytoplasm|Signal Transduction|*Transcription Factors 40 mnx1 31847880 J Hematol Oncol 2019 PMC6918594 10.1186/s13045-019-0826-2 1 0 0 116 *Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|*Macrophages|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Prognosis|Cancer-Associated Fibroblasts|*HSP90 Heat-Shock Proteins|Xenograft Model Antitumor Assays|Biomarkers, Tumor|Apoptosis|Signal Transduction|Cell Line, Tumor 159 mnx1 31843814 J. Pharmacol. Exp. Ther. 2019 10.1124/jpet.119.262949 0 0 0 116 Humans|*RNA, Long Noncoding|*RNA, Anti-Sense|*Urinary Bladder Neoplasms|*Transcription Factors|Cell Proliferation|*Oncogenes|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|*Oncogenesis|Homeodomain Proteins|Cell Line, Tumor|Up-Regulation|Epithelial-Mesenchymal Transition|Disease Progression|MNX1 protein, human|MIRN218 microRNA, human 159 mnx1 31730496 Orphanet J Rare Dis 2019 PMC6858688 10.1186/s13023-019-1208-0 0 0 0 116 Humans|*Mosaicism|Pigmentation Disorders|Karyotyping|Skin Pigmentation|Phenotype 159 mnx1 31726413 Sci. Total Environ. 2019 10.1016/j.scitotenv.2019.134870 0 0 0 116 Animals|*Zebrafish|Hedgehog Proteins|decamethrin|*Urinary Bladder|*Pyrethrins|Nitriles|*Organogenesis|Swimbladder|PTCH2 protein, human|Patched-2 Receptor|Embryo, Nonmammalian|Insecticides|Signal Transduction|PTCH protein, human|Patched-1 Receptor|Wnt1 Protein 159 mnx1 31646549 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201910_19126 0 1 0 116 *Epithelial-Mesenchymal Transition|*Osteosarcoma|*Oncogene|RNA, Long Noncoding|Homeodomain Proteins|Cell Proliferation|Gene Expression Regulation, Neoplastic|Transcription Factors|Cell Movement|Cell Line, Tumor|Disease Progression 159 mnx1 31511252 Development 2019 PMC7212092 10.1242/dev.179523 11 0 0 116 Enhancer Elements, Genetic|CCCTC-Binding Factor|Chromatin|Promoter Regions, Genetic|Gene Expression Regulation, Developmental|Binding Sites|Hedgehog Proteins 159 mnx1 31436258 Med. Sci. Monit. 2019 PMC6716296 10.12659/MSM.914233 0 0 0 116 Humans|Female|CCNE1 protein, human|*Cyclin E|*Uterine Cervical Neoplasms|*Genes, Homeobox|*Oncogene Proteins|Cell Proliferation|Homeodomain Proteins|Transcription Factors|Cell Movement|Upregulation|CCNE2 protein, human|Cyclins|RNA, Long Noncoding|*Carcinoma, Squamous Cell|HeLa Cell|*Motor Neuron|Cell Line, Tumor|*Pancreas 159 mnx1 31430329 PLoS ONE 2019 PMC6701795 10.1371/journal.pone.0221456 0 1 0 116 Humans|Mice|Animals|gastrin I|*Gastrins|*Glycated Hemoglobin A|Diabetes Mellitus, Experimental|Islet Cells|Insulin|Glucagon|Insulin Secretion|Receptor, Gastrin|Insulin-Secreting Cells|GLP 1|Glucose 159 mnx1 31416476 Hum. Genomics 2019 PMC6694645 10.1186/s40246-019-0230-6 0 0 0 116 Humans|*RNA, Long Noncoding|*Laryngeal Neoplasms|*Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|Gene Expression Profiling|ROC Curve 159 mnx1 31364121 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201907_18417 1 4 0 116 Humans|*RNA, Long Noncoding|KISS1 protein, human|*Kisspeptins|*Osteosarcoma|Homeodomain Proteins|Cell Proliferation|Cell Movement|RNA, Antisense|Gene Expression Regulation, Neoplastic|Transcription Factors|Cell Line, Tumor|Disease Progression|Up-Regulation|MNX1 protein, human 159 mnx1 31364117 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201907_18431 0 4 0 116 *RNA, Long Noncoding|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Upregulation|IGF2 protein, human|*IGF-2|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Transcriptional Activation|Homeodomain Proteins|Cell Line, Tumor|*Neoplastic Processes|Transcription Factors 159 mnx1 31210302 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201906_18057 2 4 0 116 *RNA, Long Noncoding|*Stomach Neoplasms|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|RNA, Antisense|Homeodomain Proteins|Cell Movement|Transcription Factors|Cell Line, Tumor|Up-Regulation|Apoptosis|Disease Progression 159 mnx1 31170665 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109029 5 3 0 116 *RNA, Long Noncoding|*Esophageal Squamous Cell Carcinoma|*Sirtuin 1|*Esophageal Neoplasms|*Disease Progression|Gene Expression Regulation, Neoplastic|MicroRNAs|Neoplasm Invasiveness|Cell Proliferation|Cell Movement|Cell Line, Tumor|Up-Regulation 159 mnx1 31118668 Onco Targets Ther 2019 PMC6497912 10.2147/OTT.S198014 0 1 0 116 159 MORC1 31683097 J Psychiatr Res 2019 PMC6866669 10.1016/j.jpsychires.2019.10.019 0 1 0 59 Humans|Adult|Animals|Infant, Newborn|Child|*DNA Methylation|*Depression|Epigenesis, Genetic|*Stress, Life|Epigenetic|Promoter Regions, Genetic|Receptors, Glucocorticoid|Adult Survivors of Child Abuse|Depressive Disorder, Major|*Biomarkers|Cohort Studies 26 MORC1 30897172 PLoS ONE 2019 PMC6428317 10.1371/journal.pone.0214275 0 0 0 59 Pregnancy|Male|Humans|Female|In Situ Hybridization, Fluorescence|*Infertility, Male|Spermatozoa|Pregnancy Rate|Sperm Injections, Intracytoplasmic|Aneuploidy|Semen Analysis|Abortion, Spontaneous|Chromatin|Epigenesis, Genetic 26 MPZL2 31818507 Immunobiology 2019 10.1016/j.imbio.2019.11.018 0 1 0 144 Mice|Animals|*CD11c Antigen|Encephalomyelitis, Autoimmune, Experimental|Myelin-Oligodendrocyte Glycoprotein|Cell Adhesion Molecules|B-Lymphocytes|Mice, Inbred C57BL|Cytokines|Cell Adhesion 22 MRGPRD 31473818 Cell Tissue Res. 2019 10.1007/s00441-019-03097-5 0 0 0 47 Mice|Animals|G-Protein-Coupled Receptors|*Gastrointestinal Tract|Ganglia, Spinal|Mice, Inbred C57BL|Nociception|Lamina Propria 50 MRGPRD 30919047 Cell Tissue Res. 2019 PMC6647478 10.1007/s00441-019-03017-7 0 0 0 47 Humans|Mice|Animals|Intestinal Mucosa|Intestines|Receptors, G-Protein-Coupled|Ganglia, Dorsal Root|Mice, Inbred C57BL|Sensory Neurons|Macrophages 50 MRGPRD 30918468 Mediators Inflamm. 2019 PMC6409041 10.1155/2019/2401081 1 21 0 47 angiotensin I (1-7)|alamandine|*Angiotensin I|*Peptide Fragments|*Oligopeptides|Renin-Angiotensin System|*Macrophages|Receptors, G-Protein-Coupled|Angiotensin II|Proto-Oncogene Proteins|Signal Transduction|Nitric Oxide|Anti-Inflammatory Agents 50 MRGPRD 30737255 Clin. Sci. 2019 10.1042/CS20180547 2 1 0 47 50 MRO 31654242 Surg Case Rep 2019 PMC6814676 10.1186/s40792-019-0719-1 0 0 0 123 Humans|*Robotics|*Intestinal Obstruction|*Self Expandable Metallic Stent|*Laparoscopy|Colorectal Cancer|Colonic Neoplasms|Stents 186 MRO 31508408 Front Chem 2019 PMC6716547 10.3389/fchem.2019.00585 0 0 0 123 *Wheat Bran|*Water|*Ionic Liquids|*Least-Squares Analysis|*Temperature|Hydrolysis|Xylose|Lignin|Biomass|Cellulase|Glucose|*Ions 186 MRO 31386160 J Am Med Inform Assoc 2019 10.1093/jamia/ocz090 0 0 0 123 Humans|United States|*Health Insurance Portability and Accountability Act|*Electronic Health Records|Computer Security|Health Information Technology|Health Policies 186 MRO 31374556 J Phys Condens Matter 2019 10.1088/1361-648X/ab3820 0 0 0 123 Crystallization|X-Ray Diffraction|Thermodynamics|Water|Simulations, Molecular Dynamics|Temperature 186 MRO 31279553 J. Dairy Sci. 2019 10.3168/jds.2019-16449 0 0 0 123 Cattle|Animals|Male|*Rumen|*Diet|Animal Feed|Milk Substitutes|Weaning|Fatty Acids, Volatile|Milk|Body Weight|Epithelium|Cell Proliferation|BrdU 186 MRO 31279552 J. Dairy Sci. 2019 10.3168/jds.2019-16450 1 0 0 123 Cattle|Animals|Male|*Rumen|*Fatty Acids, Volatile|*Diet|Animal Feed|Milk|Weaning|Butyrate|Propionates 186 MRO 31229453 Infect Dis Health 2019 10.1016/j.idh.2019.05.002 0 0 0 123 Humans|*Antibiotic|*Cross-Sectional Studies|*Cohort Studies|Bacterial Infections|Health Knowledge, Attitudes, Practice|Surveys and Questionnaires|*Physiological Phenomena 186 MRO 31086122 Genes (Basel) 2019 PMC6563013 10.3390/genes10050367 1 0 0 123 Entamoeba histolytica|Mitochondrion|Protozoan Proteins|Protein Transport|Biological Evolution 186 MRO 30951953 Ultramicroscopy 2019 10.1016/j.ultramic.2019.02.023 0 0 0 123 *Scanning Transmission Electron Microscopy|Silicon|Electron Microscopy|Electron 186 MRO 30902286 Food Chem 2019 10.1016/j.foodchem.2019.02.107 3 0 0 123 *Oryza|*Phenols|Solvents|Plant Extracts|Antioxidants|Chromatography, High Pressure Liquid|Sonication|*Plant Structures|Water 186 MSMB 31773691 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201911_19422 0 0 0 106 119 MSMB 31516752 Cancer Biol Med 2019 PMC6713635 10.20892/j.issn.2095-3941.2018.0384 1 0 0 106 119 MSMB 31443657 Respir. Res. 2019 PMC6708250 10.1186/s12931-019-1140-9 2 0 0 106 119 MSMB 31337649 Cancer Res. 2019 PMC6744971 10.1158/0008-5472.CAN-18-3997 0 0 0 106 119 MSMB 31308362 Nat Commun 2019 PMC6629701 10.1038/s41467-019-10808-7 3 2 0 106 119 MSMB 31226226 Int. J. Cancer 2019 PMC7028127 10.1002/ijc.32525 0 1 0 106 119 MSMB 30945244 Methods Mol. Biol. 2019 10.1007/978-1-4939-9102-0_5 0 0 0 106 119 MSMB 30893443 Res Gerontol Nurs 2019 PMC6918485 10.3928/19404921-20190206-01 0 0 0 106 119 MSMB 30774776 Oncotarget 2019 PMC6366823 10.18632/oncotarget.26592 0 0 0 106 119 MTDH 31854468 Clin. Exp. Pharmacol. Physiol. 2019 10.1111/1440-1681.13230 1 0 0 1112 Humans|*RNA, Long Noncoding|*Colorectal Cancer|MicroRNAs|Wnt Signaling Pathway|Tumorigenesis|Cell Proliferation|*Upregulation|RNA Interference|Gene Expression Regulation, Neoplastic|*Catenins|Cell Movement|beta Catenin|3' Untranslated Regions|Down-Regulation|Cell Line, Tumor|Oncogenes|*Transcriptional Activation|*Colonic Neoplasms 490 MTDH 31814886 Am J Transl Res 2019 PMC6895511 0 2 0 1112 MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|*Carcinoma, Thyroid|Lung Neoplasms|Cell Line, Tumor 490 MTDH 31814737 Onco Targets Ther 2019 PMC6863364 10.2147/OTT.S219440 0 4 0 1112 Humans|*Proto-Oncogene Proteins c-akt|*mRNA|*Osteosarcoma|PTEN protein, human|*PTEN Phosphohydrolase|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Signal Transduction|Apoptosis|Cell Adhesion Molecules|*Phenotype|MIRN618 microRNA, human 490 MTDH 31806873 Oncogene 2019 10.1038/s41388-019-1126-6 0 12 0 1112 Humans|Mice|Animals|*Triple-Negative Breast Cancer|*Sirtuin 3|Epithelial-Mesenchymal Transition|Cell Line, Tumor|*Mitochondria|Cell Adhesion Molecules|Cell Proliferation|Gene Expression Regulation, Neoplastic|Transcription Factors|metadherin, mouse|Membrane Proteins|Cell Movement|Apoptosis|*RNA Splicing|SIRT3 protein, human|MTDH protein, human|Sirt3 protein, mouse 490 MTX3 31513804 J. Invest. Dermatol. 2019 10.1016/j.jid.2019.08.443 0 1 0 133 Humans|*Administration, Cutaneous|Pilot Projects|*Oxygen|*Mycosis Fungoides|Paget's Disease, Extra-Mammary|*Skin|Skin Cancers|*Adenocarcinoma|Methotrexate|Pruritus 21 MTX3 30717108 Toxins (Basel) 2019 PMC6409949 10.3390/toxins11020079 5 0 0 133 21 MXD1 31635836 J. Surg. Res. 2019 10.1016/j.jss.2019.09.018 0 0 0 873 Humans|RNA, Micro|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|*Disease Progression|Down-Regulation|MCF-7 Cells|Cell Proliferation|Cell Movement|3' Untranslated Regions|Cell Line, Tumor|*Neoplastic Processes|Repressor Proteins|*Phenotypes|MXD1 protein, human|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|MIRN382 microRNA, human 172 MXD1 30836997 J Neuroinflammation 2019 PMC6399982 10.1186/s12974-019-1433-4 2 23 0 873 Humans|*Cerebral Hemorrhage|Transcriptome|Networks, Gene|Gene Expression Profiling|Brain|*Autophagy 172 MXD1 30606768 Mol. Cancer Res. 2019 10.1158/1541-7786.MCR-18-0991 0 8 0 873 VDR protein, human|*Receptors, Calcitriol|*Gene Expression Regulation|*Proteolysis|Calcitriol|Signal Transduction|E3 Ligase|F-Box Proteins|F-Box-WD Repeat-Containing Protein 7|Proto-Oncogene Proteins c-myc|Vitamin D|Cell Line, Tumor 172 Mxi1 31754093 Cell Death Dis 2019 PMC6872557 10.1038/s41419-019-2108-x 2 6 0 261 Humans|*Glioblastoma|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|Brain Neoplasms|Glioma|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Proliferation|Prognoses|MXI1 protein, human|Tumor Suppressor Proteins|Basic Helix-Loop-Helix Transcription Factors 182 Mxi1 31719930 Cell Mol Bioeng 2019 PMC6816687 10.1007/s12195-019-00598-9 1 0 0 261 *Optogenetics|RNA, Guide|*Gene Expression|CRISPR-Cas Systems|Gene Expression Regulation, Fungal|Synthetic Biology|Saccharomyces cerevisiae|Promoter Regions, Genetic 182 Mxi1 31221064 Biochemistry Mosc. 2019 10.1134/S0006297919030088 0 0 0 261 Humans|Adult|*Mesenchymal Stem Cells|*Oxygen|*Senescence, Replicative|Cell Differentiation|Bone Marrow Cells|Cell Proliferation|*Hypoxia|Cell Hypoxia|*Gene Expression|Cells, Cultured|Apoptosis|Signal Transduction|Aging|MXI1 protein, human|Tumor Suppressor Proteins|Basic Helix-Loop-Helix Transcription Factors 182 Mxi1 30760609 mSphere 2019 PMC6374589 10.1128/mSphere.00002-19 4 0 0 261 Humans|*Clustered Regularly Interspaced Short Palindromic Repeats|CRISPR-Associated Protein 9|CRISPR-Cas Systems|Transcription, Genetic 182 MXRA5 30662604 Am J Transl Res 2019 PMC6291708 3 3 0 21 Humans|*Computational Biology|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|*Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Prognosis|mRNA|Upregulation|Microarray Analysis|CD109 protein, human|Neoplasm Proteins|Antigens, CD|GPI-Linked Proteins|SLC6A14 protein, human|Amino Acid Transport Systems, Neutral 23 MXRA5 30598261 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2018.12.152 2 4 0 21 *Cystic Fibrosis|*Cystic Fibrosis Transmembrane Conductance Regulator|Bronchi|Epithelial Cells|Cell Line 23 MYCL 31859190 J. Biosci. Bioeng. 2019 10.1016/j.jbiosc.2019.11.013 1 0 0 170 Humans|*Myoblasts|*Muscle Contraction|*Muscle, Skeletal|Myotubes|Muscle Development|*Fibroblasts|Cell Differentiation|IGF1 protein, human|IGF-1|Tissue Engineering|Stem Cell|Cell Line|Electrical Stimulation 95 MYCL 31748534 Blood Cancer J 2019 PMC6868231 10.1038/s41408-019-0252-2 1 3 0 170 Humans|*Burkitt Lymphoma|MYCN protein, human|*N-Myc Proto-Oncogene Protein|myc Gene|B-Cell Lymphomas|Translocation, Genetic|Gene Expression Regulation, Neoplastic|MicroRNAs|mRNA|Immunohistochemistry 95 MYCL 31706097 Stem Cell Res 2019 10.1016/j.scr.2019.101630 0 0 0 170 Male|Humans|Adult|*Induced Pluripotent Stem Cells|*Cell Line|Cellular Reprogramming|Cell Differentiation|Dermis|Octamer Transcription Factor-3|Fibroblasts|Cells, Cultured|SOXB1 Transcription Factors|Kruppel-Like Transcription Factors|Plasmids 95 MYCL 31554870 Sci Rep 2019 PMC6761134 10.1038/s41598-019-50388-6 1 0 0 170 Humans|Adult|Mice|Animals|*Urinary Bladder|Urothelium|Interstitial Cystitis|*Epithelial Cells|*Fibroblasts|Urinary Tract|Cells, Cultured|*Mucosa|TP63 protein, human|Hepatocyte Nuclear Factor 3-alpha|*Regeneration|Biomarkers|Tumor Suppressor Proteins 95 MYCL 31494449 Stem Cell Res 2019 10.1016/j.scr.2019.101549 0 0 0 170 Humans|Female|Middle Aged|*Induced Pluripotent Stem Cells|Cellular Reprogramming|Octamer Transcription Factor-3|SOXB1 Transcription Factors|Kruppel-Like Transcription Factors|Cell Differentiation|Fibroblasts|Proto-Oncogene Proteins c-myc|*Mutations|Cells, Cultured|Genetic Vectors|*Retinal Dystrophies|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors 95 MYCL 31452837 Oncotarget 2019 PMC6697639 10.18632/oncotarget.27131 1 9 0 170 *Integrin beta1|*Oncogene Proteins|Neuroblastoma|Fibronectins 95 MYCL 31375684 Nat Commun 2019 PMC6677768 10.1038/s41467-019-11371-x 4 3 0 170 Humans|Mice|Animals|*Small Cell Lung Carcinoma|Lung Neoplasms|Proto-Oncogene Proteins c-myc|Cell Cycle Control|Protein Kinase Inhibitors|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|Genotoxic Stress|Signal Transduction|Miz1 protein, mouse|Nuclear Proteins|Protein Inhibitors of Activated STAT 95 MYCL 31189116 Cell Rep 2019 PMC6581744 10.1016/j.celrep.2019.05.057 4 0 0 170 Humans|Mice|Animals|*Cisplatin|Proteomics|*Small Cell Lung Carcinoma|Lung Cancer|Carcinoma, Small Cell|Drug Resistance, Neoplasm|NFIB protein, human|NFI Transcription Factors|Antineoplastic Combined Chemotherapy Protocols|CDH1 protein, human|Cadherins|Antigens, CD 95 MYCL 31164374 Clin. Cancer Res. 2019 PMC6697617 10.1158/1078-0432.CCR-18-4140 5 1 0 170 *Arginine|*Small Cell Lung Carcinoma|Lung Neoplasms|Proto-Oncogene Proteins c-myc|Cell Line, Tumor 95 MYCL 31025404 Cell Biochem. Funct. 2019 10.1002/cbf.3395 0 1 0 170 Humans|Mice|Animals|*RNA Interference|*Stomach Neoplasms|Mice, Nude|MYCL protein, human|*Proto-Oncogene Proteins c-myc|*Stomach|Neoplasm Invasiveness|Cell Movement|Cell Proliferation|Downregulation|RNA, Small Interfering|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Transfection|China 95 MYCL 30598450 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6338866 10.1073/pnas.1818798116 7 5 0 170 Mice|Animals|*Carcinoma, Merkel Cell|TP53 protein, human|*Tumor Suppressor Protein p53|Merkel cell polyomavirus|Large T-Antigen|Polyomavirus Infections|Tumor Virus Infections|*p53 Gene|Skin Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Mutations 95 MYH15 31113982 Sci Rep 2019 PMC6529472 10.1038/s41598-019-43409-x 1 1 0 40 *Transforming Growth Factor beta|*Carcinoma, Non-Small-Cell Lung|Epithelial-Mesenchymal Transition|Lung Cancer|*Cytoskeleton|Neoplasm Invasiveness|Transforming Growth Factor beta1|Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Vimentin|Upregulation 24 MYH15 30985904 Hum. Mol. Genet. 2019 PMC6606848 10.1093/hmg/ddz063 0 0 0 40 Animals|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|C9orf72 Protein|DNA Repeat Expansion|Frontotemporal Dementia|Drosophila|Dipeptides|Neurological Disorder|Age-at-Onset|Phenotypes|SALS protein, Drosophila|Microfilament Proteins|Drosophila Proteins 24 MYH15 30967136 BMC Med. Genet. 2019 PMC6454587 10.1186/s12881-019-0770-6 1 2 0 40 Paraganglioma|*Paraganglioma, Extra-Adrenal|Carotid Body Tumor|*Head and Neck Neoplasms|Mutation|Genetic Predisposition to Disease|Neoplastic Syndromes, Hereditary 24 MYH15 30906771 Biomed Res Int 2019 PMC6398074 10.1155/2019/3805405 0 0 0 40 Humans|*Myosin Heavy Chains|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Alleles|Genotype|Case-Control Studies|Asthma 24 MYH15 30836986 Skelet Muscle 2019 PMC6402096 10.1186/s13395-019-0192-3 2 0 0 40 Animals|Myosin Heavy Chains|Skeletal Muscles|Muscle Fibers, Skeletal|Muscle Contraction|Protein Isoforms|Mammals 24 MYH15 30601081 Anim. Biotechnol. 2019 10.1080/10495398.2018.1476377 1 1 0 40 24 MYO15A 31850270 Iran. J. Public Health 2019 PMC6908923 0 0 0 19 Iran|*Hearing Loss, Sensorineural|*Deafness|Genetic Testing|Connexins|Next Generation Sequencing|Mutation|Genomics 119 MYO15A 31835641 Genes (Basel) 2019 PMC6947215 10.3390/genes10121031 0 0 0 19 Humans|Pakistan|*Homozygote|Deafness|Hearing Loss|Pedigree|Hearing Loss, Sensorineural|Genetic Testing|Serine Endopeptidases|Membrane Proteins|Mutation|High-Throughput Nucleotide Sequencing|Neoplasm Proteins|*Ethnic Groups 119 MYO15A 31791989 BMJ Case Rep 2019 10.1136/bcr-2019-231978 0 0 0 19 Male|Humans|Infant, Newborn|*Cholestasis|alpha 1-Antitrypsin Deficiency|*Infant, Newborn, Diseases|Genotype|Phenotype|Syndrome|*Iron Overload|Mutation|Deafness, Autosomal Recessive 3|Hearing Loss, Sensorineural|*Hypoglycemia 119 MYO15A 31753095 Zhongguo Dang Dai Er Ke Za Zhi 2019 0 0 0 19 Female|Pregnancy|Animals|Rats|*White Matter|Rats, Sprague-Dawley|Animals, Newborn|Hypoxia-Ischemia, Brain|Myelin Basic Protein|Brain|*Brain Injuries|Disease Models, Animal|*Premature Birth|*Hippocampus 119 MYO15A 31740869 J Pak Med Assoc 2019 10.5455/JPMA.300796. 0 0 0 19 *Genetic Linkage|*Hearing Impairment|Deafness|Hearing Loss, Sensorineural|Pedigree|Genes, Recessive|Homozygote|Alleles|Chromosome Mapping|Myosins|Mutation 119 MYO15A 31581539 Genes (Basel) 2019 PMC6826657 10.3390/genes10100772 2 0 0 19 Humans|*Molecular Epidemiology|*Deafness|*Hearing Loss, Sensorineural|Hearing Loss|*Asian Continental Ancestry Group|Connexins|Sulfate Transporters|Genetic Testing|Mutations|Sequencing, Next-Generation|Cohort Studies|OTOF protein, human|Membrane Proteins 119 MYO15A 31580838 Neuropharmacology 2019 10.1016/j.neuropharm.2019.107803 0 0 0 19 Humans|Infant|Animals|Rats|Infant, Newborn|*Neuroprotective Agents|*Leptin|Preterm Infants|*Ischemia-Hypoxia, Brain|*Hippocampus|Chromatography, Liquid|Tandem Mass Spectrometry|Animals, Newborn|Brain Injuries|Brain|Peptides|Disease Models, Animal|Hypoxia 119 MYO15A 31579092 Clin Med Insights Case Rep 2019 PMC6757496 10.1177/1179547619871907 0 0 0 19 Humans|Infant, Newborn|*RNA Splicing|Homozygote|Genes, Recessive|Deafness|Hearing Loss|Pedigree|Hearing Loss, Sensorineural|Mutations|Myosins 119 MYO15A 31389194 Mol Genet Genomic Med 2019 PMC6732339 10.1002/mgg3.917 0 0 0 19 Humans|Nonsyndromic Deafness|Pakistan|*Deafness|Nonsyndromic sensorineural hearing loss|Hearing Loss, Sensorineural|Genetic Screening|Hearing Loss|Connexins|High-Throughput Nucleotide Sequencing|Mutation|Genetic Predisposition to Disease|*Cohort Studies|*Ethnic Groups|Membrane Proteins 119 MYO15A 31379920 Front Genet 2019 PMC6650584 10.3389/fgene.2019.00639 1 0 0 19 Humans|*Whole Exome Sequencing|*Hearing Loss|Genes, Recessive|Pedigree|*Chinese|Exome|Connexins|*Family|Mutation|Phenotype|*Nuclear Families 119 MYO18B 31661144 Mol Med Rep 2019 PMC6854551 10.3892/mmr.2019.10775 0 4 0 35 Humans|Myoblasts|Muscle Development|Myogenin|Cell Differentiation|MicroRNAs|Cell Proliferation|Downregulation|*Rheumatoid Arthritis|*Muscle, Skeletal|CCND1 protein, human|Cyclin D1|Cell Line|Myosin Heavy Chains|MYO18B protein, human|Myosins|Tumor Suppressor Proteins|MIRN760 microRNA, human 42 MYO18B 31508842 Anim. Genet. 2019 10.1111/age.12848 1 0 0 35 Horses|Animals|MSTN protein, human|Myostatin|*Genome|Genotypes|Phenotype|Genome-Wide Association Study|Breeding|Physical Conditioning, Animal|*Genomics|SNPs|Athletic|*DNA Mutational Analysis 42 MYO18B 31195167 Eur J Med Genet 2019 PMC7285001 10.1016/j.ejmg.2019.103701 3 0 0 35 Child|Humans|Male|Child, Preschool|*Medulloblastoma|*Klippel-Feil Syndrome|Whole Exome Sequencing|Pedigree|Exome|Brain Neoplasms|Cerebellar Neoplasms|*Comorbidity 42 MYO18B 30737279 J. Biol. Chem. 2019 PMC6509511 10.1074/jbc.RA118.004560 2 0 0 35 Mice|Animals|Homozygote|Sequence Deletion|*Sarcomeres|*Protein Isoforms|Myosin|Muscle Proteins|Myocytes, Cardiac|Golgi Apparatus|*Cytoskeletal Proteins|Muscle, Skeletal|Cells, Cultured|Myo18a protein, mouse 42 myo1f 31774725 Mol. Biol. Cell 2019 PMC6960411 10.1091/mbc.E19-08-0475 0 2 0 128 *Pleckstrin Homology Domains|Myosin Type I|Dictyostelium|Myosin|Actin Cytoskeleton|Actins|*Hydrophobic and Hydrophilic Interactions|Protozoan Proteins|Protein Transport|Cell Membrane 25 myo1f 31245869 J. Cell. Biochem. 2019 PMC6771964 10.1002/jcb.29128 3 0 0 128 Male|Humans|*Coronary Vessels|Leukocytes, Mononuclear|Coronary Artery Disease|Coronary Angiography|ST Segment Elevation Myocardial Infarction|Receiver Operating Characteristic|Gene Expression Profiling|Cohort Studies|Biomarkers|Case-Control Studies|Risk Factors|NCF2 protein, human|NADPH Oxidases|MYO1F protein, human|Myosin Type I 25 myo1f 31143189 Front Immunol 2019 PMC6521229 10.3389/fimmu.2019.01058 1 7 0 128 Humans|Cell Degranulation|Mast Cells|SH2 Domain|Stem Cell Factor|Signal Transduction|*Cell Migration|Phosphorylation|Adaptor Proteins, Signal Transducing|Carrier Proteins|Cell Line|Integrins|Actin Cytoskeleton|*Myosins|MYO1F protein, human|Myosin Type I 25 myo1f 30890704 Nat Commun 2019 PMC6425032 10.1038/s41467-019-09104-1 6 15 0 128 *Myosin I|*Phagocytosis|*Cytoskeleton|Myosins|Actin|Phagosomes|Macrophages|Cell Membrane|Receptors, IgG|*Cell Physiological Phenomena 25 myo1f 30733664 Front Neurosci 2019 PMC6353788 10.3389/fnins.2019.00002 6 0 0 128 Animals|Humans|Mice|*Microglia|*Gene Regulatory Networks|*Aging|Alzheimer Disease|Disease Models, Animal|Brain|Transcriptomes|Adaptor Proteins, Signal Transducing|Parkinson Disease 25 myo1f 30687322 Front Immunol 2019 PMC6335276 10.3389/fimmu.2018.03118 2 3 0 128 Mice|Animals|*Myosin B|*Macrophages|Macrophage Activation|Dextran Sulfate|Colitis|Cytokines|Inflammation|Colitis, Ulcerative|Inflammation Mediators|Colon|Mice, Inbred C57BL|Signal Transduction|Epithelial Cell|*Tissue Adhesions 25 MYO5C 31801962 Int J Obes (Lond) 2019 10.1038/s41366-019-0498-6 0 0 0 604 Humans|*DNA Methylation|*Body Mass Index|CpG Islands|Epigenetic|Epigenesis, Genetic|Twins, Monozygotic|Genome-Wide Association Study 22 MYO5C 31022261 PLoS ONE 2019 PMC6483353 10.1371/journal.pone.0215913 7 0 0 604 Female|Pregnancy|Horses|Male|Animals|*Breeding|Haplotype|Homozygote|Genotype|Selection, Genetic|Genomes|*Sport|Phenotypes|Genomics|Polymorphism, Single Nucleotide|Fertility|Crossbreeding|Principal Component Analysis 22 MYOF 31828126 Biomed Res Int 2019 PMC6885792 10.1155/2019/7365913 0 0 0 181 Humans|*Membrane Protein|Epithelial-Mesenchymal Transition|Muscle Proteins|Calcium-Binding Proteins|*Oncogenes|Cell Motility|*Oncogenesis|Cell Line, Tumor|Neovascularization, Pathologic|Endocytosis|MYOF protein, human 88 MYOF 31650199 Cancer Immunol. Immunother. 2019 10.1007/s00262-019-02408-7 1 0 0 181 Humans|*Prognosis|*Data Analysis|*Leukemia, Myeloid, Acute|Protein Interaction Maps|Bioinformatics|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Databases, Genetic|Biomarkers, Tumor|Tumor Microenvironment|Kaplan-Meier Estimate|Gene Expression|Algorithm|MYOF protein, human|Calcium-Binding Proteins|Membrane Proteins|Muscle Proteins 88 MYOF 31623157 Int J Mol Sci 2019 PMC6829482 10.3390/ijms20205130 0 6 0 181 *Muscle Development|Myoblasts|Wnt Signaling Pathway|*Autophagy|Dishevelled Proteins|Cell Differentiation|*Catenins|beta Catenin|TRIM63 protein, human|Muscle Proteins|Ubiquitination|Tripartite Motif Proteins|Ubiquitin-Protein Ligases 88 MYOF 31477752 Sci Rep 2019 PMC6718427 10.1038/s41598-019-48968-7 0 7 0 181 Humans|*Carcinoma, Renal Cell|Vascular Endothelial Growth Factor A|KDR protein, human|*VEGFR-2|Kidney Neoplasms|Calcium-Binding Proteins|Muscle Proteins|Membrane Proteins|Melanoma, Cutaneous Malignant|Malignant Melanoma|Cell Line, Tumor|Downregulation|Skin Neoplasms|Cellular Proliferation|MYOF protein, human 88 MYOF 31477299 J. Dairy Sci. 2019 10.3168/jds.2019-17068 1 0 0 181 Pregnancy|Cattle|Animals|Female|Male|Lactation|Fertility|*Phenotype|Genotype|Reproduction|Breeding|Conception|Pregnancy Rate|Polymorphism, Single Nucleotide|Genome|Genetic Markers|*Lipids 88 MYOF 31443490 Cells 2019 PMC6770723 10.3390/cells8090954 1 2 0 181 Animals|Humans|Endothelial Cells|OTOF protein, human|Membrane Proteins|Dysferlin|Muscle Proteins|Calcium-Binding Proteins|Cell Membrane|*Membrane|Cell Proliferation 88 MYOF 31421995 Urol. Oncol. 2019 10.1016/j.urolonc.2019.07.002 1 1 0 181 *Carcinoma, Renal Cell|*Prognosis|Kidney Neoplasms|EGFR protein, human|*Epidermal Growth Factor Receptor|Biomarkers, Tumor|Kaplan-Meier Estimate|Cytoplasm|Staining and Labeling 88 MYOF 31297131 Front Genet 2019 PMC6607695 10.3389/fgene.2019.00608 2 1 0 181 Humans|Muscular Dystrophies, Limb-Girdle|Phenotype|Muscle Proteins|Exome|Muscle, Skeletal|Sequencing, Whole Exome|Mutation|Cardiomyopathies 88 MYOF 31288815 BMC Womens Health 2019 PMC6617862 10.1186/s12905-019-0795-1 0 1 0 181 Female|Humans|*Progesterone|*Uterine Fibroids|*Myometrium|progesterone receptor B|Progesterone Receptor|Uterine Neoplasms|Receptors, Estrogen|Estrogens|Steroids|MYOF protein, human|Calcium-Binding Proteins|Membrane Proteins|Muscle Proteins 88 MYOF 31283102 Cell. Microbiol. 2019 PMC6851706 10.1111/cmi.13082 2 0 0 181 Animals|*Parasites|*Myosins|Protozoan Proteins|Plasmodium berghei|Sporozoite|Actin|Apicomplexa|Life Cycle|Cell Movement 88 MYOF 31280198 In Vivo 2019 PMC6689344 10.21873/invivo.11579 2 0 0 181 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Prognosis|Neoplasm Grading|Neoplasm Staging|Biomarkers, Tumor 88 MYOF 31026162 J. Med. Chem. 2019 10.1021/acs.jmedchem.9b00059 3 0 0 181 Humans|Mice|Animals|1,2,4-triazole|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Triazoles|Cell Movement|Epithelial-Mesenchymal Transition|Xenograft Model Antitumor Assays|Mice, Nude|Cell Line, Tumor|Antineoplastic Agents|Cell Proliferation|Receptor Protein-Tyrosine Kinases|Apoptosis|Signal Transduction|MYOF protein, human|Calcium-Binding Proteins|Membrane Proteins|Muscle Proteins 88 Myrf 31883016 J. Nutr. 2019 10.1093/jn/nxz330 0 0 0 290 Animals|Mice|*Tocopherol|*Myelin Sheath|*TTPA|*Vitamin E|*Mice, Knockout|alpha-Tocopherol|Animal Feed|Diet|Dietary Supplements|Vitamins|Liver|*Downregulation 62 Myrf 31828317 Nucleic Acids Res. 2019 PMC7026603 10.1093/nar/gkz1158 0 4 0 290 *SOXE Transcription Factors|Oligodendrocytes|Myelin|Transcription Factors|Cell Differentiation|Central Nervous System|*Neurogenesis|Binding Sites|Membrane Proteins|Cells, Cultured 62 Myrf 31782037 Cell. Mol. Neurobiol. 2019 10.1007/s10571-019-00764-7 0 8 0 290 Animals|Chick Embryo|*SOXE Transcription Factors|Oligodendrocytes|Myelin|Transcription Factor|OLIG2 protein, human|Oligodendrocyte Transcription Factor 2|Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|Neurogenesis|Gene Expression Regulation, Developmental|Stem Cells|Notch Receptors|Signal Transduction|Cells, Cultured 62 Myrf 31769911 Cell Biol. Int. 2019 10.1002/cbin.11270 1 8 0 290 *Apoptosis|RNA, Long Noncoding|MicroRNAs|RNA Interference|Cell Proliferation|Cell Movement|Smooth Muscle Cells|RNA, Messenger|Cell Line, Tumor|*Aneurysm 62 Myrf 31700225 Mol. Vis. 2019 PMC6817736 1 0 0 290 Nanophthalmos 1|*Microphthalmos|Hyperopia, High|*Hyperopia|*Glaucoma, Angle-Closure|*Eye Diseases, Hereditary|*Frameshift Mutation|Pedigree|Mutation|Membrane Proteins 62 Myrf 31363138 Sci Rep 2019 PMC6667464 10.1038/s41598-019-47521-w 1 0 0 290 Chromatin|Enhancer Elements, Genetic|Transcription Factors|Oligodendrocytes|Transcriptional Networks 62 Myrf 31361310 Hum. Mol. Genet. 2019 PMC6969355 10.1093/hmg/ddz175 7 0 0 290 Humans|*Rhinitis, Allergic, Seasonal|*Genome-Wide Association Study|United Kingdom|*Biological Specimen Banks|*Eczema|*Asthma|Single Nucleotide Polymorphisms|*European Continental Ancestry Group|Genetic Predisposition to Disease|Genetic Loci|Phenotype|Genotype|Linkage Disequilibrium|TSPAN8 protein, human|Tetraspanins 62 Myrf 31312492 R Soc Open Sci 2019 PMC6599778 10.1098/rsos.190266 0 3 0 290 Oligodendroglia|Myelin Sheath|Cell Differentiation|Cells, Cultured|Multiple Sclerosis 62 Myrf 31289371 Eur. J. Hum. Genet. 2019 PMC6871090 10.1038/s41431-019-0465-7 0 0 0 290 Humans|*CHARGE Syndrome|*Virulence|HeLa Cells|DNA Helicases|*Mutant Proteins|DNA-Binding Proteins|Chromatin|Phenotype|Mutation|Amino Acid Sequence|SOX4 protein, human|SOXC Transcription Factors|CHD7 protein, human 62 Myrf 31266062 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.18-26275 3 0 0 290 Humans|*Microphthalmos|Hyperopia, High|Hyperopia|Eye Diseases, Hereditary|*Sequencing, Whole Genome|*Chinese|Mutations|Pedigree|Membrane Proteins|Transcription Factors|Glaucoma, Angle-Closure 62 Myrf 31172260 Hum. Genet. 2019 PMC6745028 10.1007/s00439-019-02039-z 2 0 0 290 Humans|Hyperopia, High|*Hyperopia|*Eye Diseases, Hereditary|Microphthalmos|Pedigree|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Mutation|Angle Closure Glaucoma|Genetic Linkage|Refractive Error|Exome|Heterozygote|Frameshift Mutation|Chinese|Membrane Proteins|Transcription Factors 62 Myrf 31081019 Nucleic Acids Res. 2019 PMC6614847 10.1093/nar/gkz376 3 3 0 290 Animals|Mice|*Oligodendrocyte|Myelin|*Central Nervous System|Myelin Basic Protein|Cell Differentiation|Spinal Cord|SOXE Transcription Factors|Transcription Factors|Mice, Transgenic|Cell Proliferation|*Vertebrate|Gene Expression Regulation|Cells, Cultured|Chromatin 62 MZB1 31877723 Cancers (Basel) 2019 PMC7017323 10.3390/cancers12010037 0 0 0 35 Humans|Female|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Squamous Cell Carcinoma|Adenocarcinoma|Lung Adenocarcinoma|Gene Regulatory Networks|Transcriptome Profile|Gene Ontology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Uterine Cervical Neoplasms 25 MZB1 31127044 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6613140 10.1073/pnas.1904204116 5 2 0 35 Mice|Animals|*Gastrointestinal Microbiome|*Immunoglobulin J-Chains|Immunoglobulin A|Colitis|Immunoglobulin M|Immunoglobulin A, Secretory|Intestinal Mucosa|*Inflammation|Biological Transport|Homeostasis 25 MZB1 31050855 Protein Sci. 2019 PMC6566547 10.1002/pro.3635 0 0 0 35 Animals|Endoplasmic Reticulum|Protein Folding|Disulfides|Dithiothreitol|Oxidation-Reduction|Biological Transport|LDLR protein, human|Low Density Lipoprotein Receptor|Cysteine 25 MZB1 30885419 J. Autoimmun. 2019 10.1016/j.jaut.2019.03.004 2 0 0 35 Humans|*Aqueous Humor|*Arthritis, Juvenile|*Proteomics|*Transcriptome|Anterior Uveitis|*Uveitis|HLA-B27 Antigen|*Iris|*Iris Plant|Acute Disease|Immunoassay 25 MZB1 30653263 J. Periodontol. 2019 10.1002/JPER.18-0477 1 0 0 35 *Chronic Periodontitis|*Proteomics|*Gingiva|*Genomics|Tandem Mass Spectrometry|Transcriptomes 25 MZB1 30622539 Front Immunol 2019 PMC6308164 10.3389/fimmu.2018.03053 14 0 0 35 25 MZF1 31607299 Zhongguo Shi Yan Xue Ye Xue Za Zhi 2019 10.19746/j.cnki.issn.1009-2137.2019.05.017 0 3 0 334 Humans|Child|*Leukemia, Monocytic, Acute|*Transcription Factor|*Gene Expression Regulation|Apoptosis Regulatory Proteins|Antigens, Neoplasm|Apoptosis|Cell Proliferation 165 MZF1 31592410 Adv Sci (Weinh) 2019 PMC6774027 10.1002/advs.201900581 2 5 0 334 Transcription Factors|Kruppel-Like Transcription Factors|Neuroblastoma|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Promoter Regions, Genetic 165 MZF1 31582966 Neural Plast. 2019 PMC6754943 10.1155/2019/2782417 0 4 0 334 Rats|Animals|*Ganglia, Spinal|*Pain, Neuropathic|Hyperalgesia|Pain Threshold|Rats, Sprague-Dawley|Constriction|Trpv1 protein, rat|TRPV Cation Channels 165 MZF1 31548308 J. Biol. Chem. 2019 PMC6851318 10.1074/jbc.RA119.009779 1 5 0 334 Mice|Animals|*Transcription Factor|Kruppel-Like Transcription Factors|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Differentiation|MTOR protein, human|TOR Serine-Threonine Kinases|RNA, Messenger|Serine Threonine Kinase 165 MZF1 31396914 Methods Mol. Biol. 2019 10.1007/978-1-4939-9608-7_18 0 0 0 334 Protein Conformation|Proteins|Nuclear Magnetic Resonance, Biomolecular|Molecular Dynamics Simulation|Protein Folding 165 MZF1 31366500 Anticancer Res. 2019 10.21873/anticanres.13574 1 8 0 334 Humans|*Triple Negative Breast Neoplasms|*Downregulation|IGF1R protein, human|*Receptors, Somatomedin|*Signal Transduction|Cell Movement|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|*MAP Kinase Signaling System|MicroRNAs|Cell Line, Tumor|Cell Proliferation|Insulin-Like Growth Factor I, Resistance To|*Growth Disorders|*Abnormalities, Multiple|*Phenotype|Zinc Fingers|p38 Mitogen-Activated Protein Kinases 165 MZF1 31301870 Surgery 2019 10.1016/j.surg.2019.05.042 0 4 0 334 Humans|*Cancer-Associated Fibroblasts|MCF-7 Cells|Osteopontin|Epithelial-Mesenchymal Transition|Neoplastic Stem Cells|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Mesenchymal Stem Cells|Transforming Growth Factor beta1|Signal Transduction|Zinc Fingers 165 MZF1 31194009 Mol Ther Methods Clin Dev 2019 PMC6545354 10.1016/j.omtm.2019.05.003 0 10 0 334 Humans|Rats|Animals|*Endothelin-1|*Vascular Endothelial Growth Factor A|*Mesenchymal Stem Cells|Mesenchymal Stem Cell Transplantation|Myocardial Infarction|*Vascular Endothelial Growth Factors|*Signal Transduction|Neovascularization, Physiologic|Fetal Blood|CDH2 protein, human|Antigens, CD|Cadherins 165 MZF1 31184423 J. 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Res. 2019 10.1007/s12026-019-9067-2 4 3 0 334 Humans|*Inflammatory Bowel Disease|Lithostathine|Colitis, Ulcerative|STAT3 protein, human|STAT3 Transcription Factor|Intestinal Mucosa|Crohn's Disease|Pancreatitis-Associated Proteins|HT 29 Cells|RNA, Messenger|Colon|Promoter Regions, Genetic|TEAD4 protein, human|DNA-Binding Proteins|Muscle Proteins|Transcription Factors 165 MZF1 30654933 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.01.029 0 0 0 334 Humans|Adult|Mice|Animals|*Exons|Receptor, Platelet-Derived Growth Factor alpha|Proto-Oncogene Proteins c-kit|Gastrointestinal Stromal Tumors|*Carrier Proteins|Intron|Mutation|Promoter Regions, Genetic 165 MZF1 30622337 Oncogene 2019 PMC6525100 10.1038/s41388-018-0653-x 5 3 0 334 *Phosphorylation|*Serine|ERBB2 protein, human|*Receptor, ErbB-2|Signal Transduction|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|*Lysosome|Cell Line, Tumor|CTCFL protein, human|Kruppel-Like Transcription Factors|PRKCA protein, human|Protein Kinase C-alpha|Promoter Regions, Genetic|Zinc Fingers 165 nanos2 31693487 J. 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Biochem. 2019 10.1007/s10695-019-00693-8 2 0 0 136 Female|Male|Animals|*Ovary|*Transcriptome|Gonads|Testes|Sex Differentiation|Gametogenesis|Sexual Dimorphism|Gene Expression Regulation, Developmental|*Fishes|Reproduction|Gene Expression Profiling 118 nanos2 31348956 Gen. Comp. Endocrinol. 2019 10.1016/j.ygcen.2019.113227 0 3 0 136 Animals|Male|*Testis|*Oreochromis niloticus|*Temperature|Spermatogonia|Gonads|11-ketotestosterone|Testosterone|Reproduction 118 nanos2 31328782 Mol. Hum. Reprod. 2019 10.1093/molehr/gaz043 0 3 0 136 Humans|Male|Animals|Swine|*Haploidy|Spermatogonia|Spermatogenesis|Spermatids|Seminiferous Tubule|Spermatozoa|Testis|Retinoic Acid|Sertoli Cells|Cell Differentiation|Meiosis|Akrosin|Oocytes|*Hematopoiesis|Adult Germline Stem Cells|Adaptor Proteins, Signal Transducing 118 nanos2 31321684 Transgenic Res. 2019 10.1007/s11248-019-00134-5 1 0 0 136 Animals|*Gene Editing|Crops, Agricultural|Genetic Engineering|Plant Breeding|Plants, Genetically Modified|Livestock|Genome, Plant|Breeding|Animal Husbandry|Genomics 118 nanos2 31254043 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03201-6 2 0 0 136 Humans|Male|Animals|*Spermatogenesis|Spermatogonia|Adult Germline Stem Cells|Testis|Stem Cell|*Fertility|Cell Differentiation|Infertility, Male|Cells, Cultured|*Mammals 118 nanos2 31159444 Int J Mol Sci 2019 PMC6600436 10.3390/ijms20112705 0 0 0 136 Male|Female|Humans|Animals|*Sea Urchin|Testis|Gonads|*Cloning, Molecular|Germ Cells|Ovary|Gametogenesis|Sex Differentiation|Embryogenesis|RNA-Binding Proteins|Gene Expression Regulation, Developmental|Gene Expression Profiling|Forkhead Box Protein L2|RNA, Messenger|In Situ Hybridization|China 118 nanos2 31097079 Reprod. Fertil. Dev. 2019 10.1071/RD18488 0 0 0 136 Animals|Male|Female|*Sex Differentiation|*Oreochromis niloticus|Gonads|SOX9 protein, human|*SOX9 Transcription Factor|Spermatogonia|Methyltestosterone|Disorders of Sex Development|Testis|Sertoli Cells|Cell Differentiation 118 nanos2 31095680 Biol. Reprod. 2019 PMC6614578 10.1093/biolre/ioz075 2 0 0 136 Mice|Animals|Swine|Cattle|*CRISPR-Cas Systems|*CRISPR|Gene Editing|RNA, Guide|*Genetic Engineering|Zygote|*Electroporation|*Mammalian Embryos|Endonucleases|Embryo Transfer|Ribonucleoproteins 118 nanos2 31075220 Dev. Biol. 2019 PMC6848975 10.1016/j.ydbio.2019.04.010 0 0 0 136 Animals|*Germ Line|Strongylocentrotus purpuratus|Gastrulation|Gene Expression Regulation, Developmental|Sea Urchin|RNA Binding Protein|Mesoderm|Signal Transduction|*Neurons 118 nanos2 31029848 Theriogenology 2019 10.1016/j.theriogenology.2019.04.016 0 0 0 136 Cattle|Animals|Male|Mice|*Glial Cell Line-Derived Neurotrophic Factor Receptors|Spermatogonia|Adult Germline Stem Cells|Testis|Spermatogenesis|Stem Cells|ZBTB16 protein, human|Promyelocytic Leukemia Zinc Finger Protein|Glial Cell Line-Derived Neurotrophic Factor|Cell Differentiation|UCHL1 protein, human|Ubiquitin Thiolesterase|*Biomarkers|Fluorescence Activated Cell Sorting|Transplantation, Heterologous 118 nanos2 31007462 J Hum Reprod Sci 2019 PMC6472198 10.4103/jhrs.JHRS_9_18 1 0 0 136 Humans|Female|Pregnancy|Male|Mice|Animals|Sperm Motility|Sperm|Infertility, Male|Fertility|Germ Cells|Reproduction|Cell Differentiation|beta-Defensins|*Biomarkers|Amyloid beta-Protein Precursor|RBM5 protein, human|DNA-Binding Proteins|RNA-Binding Proteins|Cell Cycle Proteins|Tumor Suppressor Proteins 118 ncln 31508332 Bioimpacts 2019 PMC6726750 10.15171/bi.2019.21 0 0 0 65 21 NCOA4 31880208 Autophagy 2019 10.1080/15548627.2019.1709764 1 0 0 263 Mice|Animals|*Ameloblasts|*Iron|*Incisor|Autophagy|*Aging|Homeostasis|Atg7 protein, mouse|Autophagy-Related Protein 7 211 NCOA4 31715421 Cancer Treat. Rev. 2019 10.1016/j.ctrv.2019.101911 0 0 0 263 Humans|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Protein Kinase Inhibitors|cabozantinib|Pyridines|Proto-Oncogene Proteins c-ret|regorafenib|Phenylurea Compounds|lenvatinib|Antineoplastic Agents|N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine|Piperidines|Oncogene Proteins, Fusion|Adenocarcinoma|Tyrosine Kinase|Cell Line, Tumor|Quinolines|Mutation 211 NCOA4 31697865 APMIS 2019 10.1111/apm.13009 0 0 0 263 *Carcinoma, Intraductal, Noninfiltrating|Neoplasm Recurrence, Local|Salivary Gland Neoplasms|*Salivary Glands|Immunohistochemistry|Gene Fusion|Mammaglobin A|Biomarkers, Tumor|In Situ Hybridization, Fluorescence|Oncocytes 211 NCOA4 31687807 Chem. Res. Toxicol. 2019 10.1021/acs.chemrestox.9b00350 0 4 0 263 Humans|*Ferritin|pentabromodiphenyl ether|*Halogenated Diphenyl Ethers|Iron|Autophagy|Nuclear Receptor Coactivators|*Quinones|quinone|*Benzoquinones|Reactive Oxygen Species|Homeostasis|NCOA4 protein, human 211 NCOA4 31679460 Autophagy 2019 10.1080/15548627.2019.1687985 0 7 0 263 *Hepatic Stellate Cells|*Ferroptosis|thiamine triphosphorate|*Autophagy|*Signal Transduction|TYRP1 protein, human|*Membrane Glycoproteins|Programmed Cell Death|*Protective Agents|Cell Death|Lipid Peroxidation|Iron|RNA Binding Protein 211 NCOA4 31653970 Sci Rep 2019 PMC6814827 10.1038/s41598-019-51981-5 1 0 0 263 Humans|*Cetuximab|*Colorectal Cancer|Panitumumab|Proto-Oncogene Proteins B-raf|ErbB Receptors|Drug Resistance, Neoplasm|Mutations|Antibodies, Monoclonal|*Genomics|Antibodies, Monoclonal, Humanized|Class I Phosphatidylinositol 3-Kinases|Antineoplastic Agents|Phosphatidylinositol 3-Kinases|Biomarkers, Tumor|FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|Protein Kinase Inhibitors|*Colonic Neoplasms 211 NCOA4 31323811 Genes (Basel) 2019 PMC6678189 10.3390/genes10070547 0 0 0 263 Humans|Male|*Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genetic Predisposition to Disease|Alleles|Quantitative Trait Loci|Prostatic Neoplasms|Genotype|DNA Binding Protein|Protein Binding|Gene Expression Regulation, Neoplastic|Nucleotides 211 NCOA4 31320987 Oxid Med Cell Longev 2019 PMC6610730 10.1155/2019/8753413 1 5 0 263 *Epithelial-Mesenchymal Transition|Iron Chelating Agents|Cell Line, Tumor|Iron|Reactive Oxygen Species|Transforming Growth Factor beta1 211 NCOA4 31316058 Nat Commun 2019 PMC6637122 10.1038/s41467-019-10991-7 11 0 0 263 Mice|Animals|*Ferroptosis|Ferritin|*Chronic Obstructive Pulmonary Disease|Iron|*Smoke|*Epithelial Cell|Lipid Peroxidation|Autophagy|Reactive Oxygen Species|Lung|Homeostasis|Oxidative Stress|ferrostatin-1|Cyclohexylamines|Phenylenediamines|Smoking|NcoA4 protein, mouse|Nuclear Receptor Coactivators 211 NCOA4 31308362 Nat Commun 2019 PMC6629701 10.1038/s41467-019-10808-7 0 2 0 263 Humans|Male|*Transcriptome|*Prostate Cancer|Transcriptional Regulator ERG|AR protein, human|Androgen Receptor|Prostate|TMPRSS2 protein, human|Serine Endopeptidases|Oncogene Proteins, Fusion|Oncogene Fusion|Gene Expression Regulation, Neoplastic|Trans-Activators|RNA, Long Noncoding|Cohort Studies|HOXA4 protein, human|Homeodomain Proteins 211 NCOA4 31226468 Bioorg. Chem. 2019 10.1016/j.bioorg.2019.103052 1 7 0 263 Humans|*Nicotinamide|Neoplasm Recurrence, Local|*Lung Adenocarcinoma|Protein Kinase Inhibitors|Carcinoma, Non-Small-Cell Lung|Proto-Oncogene Proteins c-ret|Lung Neoplasms|N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine|Quinazolines|Adenocarcinoma|Antineoplastic Agents|Piperidines|Oncogene Proteins, Fusion|Gene Rearrangement|Sorafenib|apatinib|Cell Line, Tumor|Xenograft Model Antitumor Assays 211 NDFIP2 31096062 Mol. Immunol. 2019 10.1016/j.molimm.2019.04.006 0 0 0 108 Mice|Animals|*Introns|*Nested Genes|*Lymphocyte Activation|*Signal Transduction|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|CD3 Complex|CD4 Antigens|Cell Differentiation|Down-Regulation|Up-Regulation 24 NDFIP2 30893602 Cell Rep 2019 PMC6913780 10.1016/j.celrep.2019.02.080 1 2 0 108 Animals|Nerve Tissue Proteins|Receptors, Immunologic|*Axons|Drosophila|*Spinal Cord|TYRP1 protein, human|*Membrane Glycoproteins|Drosophila Proteins|Neurons|Gene Expression Regulation, Developmental|Cell Movement|Protein Transport|Nedd4 Ubiquitin Protein Ligases|Nedd4 protein, Drosophila 24 NEFH 31788332 Aging Dis 2019 PMC6844596 10.14336/AD.2019.0215 0 0 0 382 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Neurodegenerative Diseases|RNA-Binding Protein FUS|*Chinese|Superoxide Dismutase-1|Mutations|Genetic Association Studies|Genetic Predisposition to Disease|Superoxide Dismutase|Pedigree|DNA-Binding Proteins|Mutation Frequency|Cohort Studies 89 NEFH 31701227 Acta Neuropathol. 2019 10.1007/s00401-019-02093-x 1 0 0 382 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Proteomics|Neurodegenerative Diseases|*Biomarkers|*Spinal Cord|UCHL1 protein, human|*Ubiquitin Thiolesterase|Proteome|Neurofilament|*Transcription Factors|Case-Control Studies|Cohort Studies|GPNMB protein, human|Membrane Glycoproteins 89 NEFH 31669185 Prog. Neurobiol. 2019 PMC6938554 10.1016/j.pneurobio.2019.101718 1 0 0 382 Humans|*Stuttering|*Intermediate Filaments|Speech|Transferases (Other Substituted Phosphate Groups)|Brain|Mutations|mannose-6-phosphate|Mannosephosphates|*Lysosomes|Phosphoric Diester Hydrolases|Magnetic Resonance Imaging|GNPTG protein, human 89 NEFH 31622527 Traffic 2019 10.1111/tra.12706 0 0 0 382 Animals|Humans|*Caenorhabditis elegans|*Axonal Transport|Caenorhabditis elegans Proteins|Axons|Neurons|Nerve Tissue Proteins|Neurofilament|Cytoskeleton|KIF1A protein, human|Kinesin 89 NEFH 31475037 Front Genet 2019 PMC6707335 10.3389/fgene.2019.00732 2 0 0 382 Humans|*Amyotrophic Lateral Sclerosis|Neurodegenerative Diseases|Hungary|C9orf72 Protein|*Genetic Testing|Superoxide Dismutase-1|Genetic Association Studies|Genetic Predisposition to Disease|*Cohort Studies|Genetic Variation|High-Throughput Nucleotide Sequencing|Mutation 89 NEFH 31201651 Mol. Neurobiol. 2019 PMC6834541 10.1007/s12035-019-01643-4 2 0 0 382 Humans|Animals|Mice|Infant|*Machado-Joseph Disease|*Phosphoproteins|Glycogen Synthase Kinase 3|Proteomics|Neurodegenerative Diseases|Ataxin-3|*Brain|Nerve Tissue Proteins|Nuclear Proteins|TCL1B protein, human|Transcription Factors|Repressor Proteins|DNA-Binding Proteins|Neurons|polyglutamine|Peptides|Disease Models, Animal 89 NEFH 31142229 Autophagy 2019 PMC6999640 10.1080/15548627.2019.1615302 7 0 0 382 Animals|Humans|Mice|*Autophagosomes|*Adaptor Proteins, Signal Transducing|Autophagy-Related Proteins|Adaptor Protein Complex 4|*Protein Transport|*Axons|Membrane Proteins|Vesicular Transport Proteins|Autophagy|*Protein Deficiency|Knockout Mouse|HeLa Cells|*Cell Movement|Atg9a protein, human|Atg9A protein, mouse 89 NEFH 31118040 J Transl Med 2019 PMC6530130 10.1186/s12967-019-1909-0 3 0 0 382 Humans|*Amyotrophic Lateral Sclerosis|*Biomarkers|Gene Expression Profiling|*Hypoxia|*Leukocyte Disorders 89 NEFH 30992180 Neuromuscul. Disord. 2019 10.1016/j.nmd.2019.02.007 0 0 0 382 Humans|*Charcot-Marie-Tooth Disease|*Frameshift Mutation|*Intermediate Filaments|Austria|neurofilament protein H|Neurofilament Proteins|Pedigree|Phenotype|Axons|Mutation|Sural Nerve|Muscle Weakness|Atrophy|Peptides 89 NEFH 30927350 Cereb. Cortex 2019 PMC6918932 10.1093/cercor/bhz054 2 0 0 382 Humans|Animals|Mice|Phylogeny|*Diffusion Tractography|White Matter|*Brain|Neural Pathways|Connectome|Cerebral Cortex|Macaca mulatta|Diffusion Magnetic Resonance Imaging|*Projection|neurofilament protein H|Neurofilament Proteins|Callithrix 89 NEFH 30833663 Sci Rep 2019 PMC6399448 10.1038/s41598-019-40102-x 1 0 0 382 Humans|Animals|Mice|*Whole Exome Sequencing|*Parkinson Disease|*DNA Copy Number Variations|Exome|Sequencing, Next-Generation|Sequence Analysis, DNA|Genetic Predisposition to Disease|Mutation|Phenotype|Bcor protein, mouse|Repressor Proteins|ATP13A2 protein, mouse|Adenosine Triphosphatases|Membrane Proteins 89 NEFH 30805013 Stem Cells Int 2019 PMC6362483 10.1155/2019/9704945 1 3 0 382 Adult|Humans|*Human Induced Pluripotent Stem Cells|*Laminin|Cell Differentiation|*Cell Proliferation|Cell Culture Techniques|Fibroblasts|laminine|*Amino Acids, Diamino|*Cell Cycle 89 NEIL3 31784740 Mutagenesis 2019 10.1093/mutage/gez047 0 0 0 86 Humans|*DNA Glycosylases|*DNA|FLJ10858 protein, human|DNA Repair|DNA-(Apurinic or Apyrimidinic Site) Lyase|DNA Damage|Oligonucleotides|Guanosine|DNA, Single-Stranded|Kinetics|dihydrouracil|Uracil|Escherichia coli|Oxidation-Reduction|NEIL1 protein, human 87 NEIL3 31614656 Cancers (Basel) 2019 PMC6826995 10.3390/cancers11101539 2 0 0 86 PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|*DNA Repair|EP300 protein, human|*E1A-Associated p300 Protein|Transcription, Genetic|Chromatin|Chromatin Assembly and Disassembly|Nucleosomes|DNA Helicases|Transcription Factors|Nuclear Proteins|Promoter Regions, Genetic|Chromosomal Proteins, Non-Histone|Histone|DNA Damage|Acetylation|Protein Processing, Post-Translational 87 NEIL3 31241930 J. 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Chem. 2019 PMC6879349 10.1074/jbc.RA119.008631 0 0 0 171 *Glutamate|*Kainic Acid|Gluk2 kainate receptor|*Receptors, Kainate|TYRP1 protein, human|*Membrane Glycoproteins|*Binding Sites|Membrane Proteins|Patch-Clamp Techniques|LDL-Receptor Related Proteins|Protein Transport 53 NETO2 31514295 Int J Mol Sci 2019 PMC6770575 10.3390/ijms20184482 3 2 0 171 Lung Adenocarcinoma|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Lung Neoplasms|Cell Proliferation|Cell Line, Tumor|Downregulation|Oncogenes|Gene Expression Profiling|Kaplan-Meier Estimate 53 NETO2 31239769 Cancer Manag Res 2019 PMC6560188 10.2147/CMAR.S204260 0 2 0 171 53 NETO2 31097021 J Transl Med 2019 PMC6524242 10.1186/s12967-019-1908-1 4 0 0 171 Humans|*Gene Regulatory Networks|*Gliomas|*Prognosis|Brain Neoplasms|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|*Macrophage|Biomarkers, Tumor|Tumor Microenvironment|Computational Biology 53 NETO2 31044365 Mol. Neurobiol. 2019 PMC6815322 10.1007/s12035-019-1612-4 1 1 0 171 *Receptors, Kainic Acid|*Interneurons|CA3 Stratum Radiatum|Receptors, N-Methyl-D-Aspartate|Synapses|Neurons|Membrane Proteins|Hippocampus|LDL-Receptor Related Proteins|Kainate|Protein Binding 53 NETO2 30975469 Biochem. Biophys. Res. 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Neurol. 2019 10.1016/j.expneurol.2019.112966 0 0 0 512 *Up-Regulation|bHLH Transcription Factors|Neurons|Nerve Tissue Proteins|Cell Differentiation|Transcription Factors|Stem Cells|*Transcriptional Activation|Gene Expression Regulation, Developmental|Cells, Cultured|DNA 330 neurophysin 31843012 BMC Psychol 2019 PMC6915978 10.1186/s40359-019-0356-2 0 0 0 0 Infant|Humans|Male|Child, Preschool|Child|*Oxytocin|*Fathers|Double-Blind Method|AVP protein, human|*Vasopressin|*Neurophysins|Administration, Intranasal|Parenting|Emotions|Brain 1468 neurophysin 31823700 Curr Pharm Biotechnol 2019 10.2174/1389201021666191211152754 0 0 0 0 *Hemidesmus|*Ethanol|Plant Extracts|Antioxidants|Medicinal Plants|Medicine, Ayurvedic|Plant Roots 1468 neurophysin 31785344 Mol. Cell. 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Neuroendocrinol. 2019 10.1111/jne.12815 0 1 0 0 Mice|Animals|*Oxytocin|*Stains|Supraoptic Nucleus|AVP protein, human|Vasopressin|Neurophysins|Paraventricular Nucleus|Hypothalamus|Arginine Vasopressin|*Neurons|Suprachiasmatic Nucleus|Immunohistochemistry|Protein Precursors|*Antibodies, Monoclonal|*Staining 1468 neurophysin 31757777 EBioMedicine 2019 PMC6921366 10.1016/j.ebiom.2019.11.011 0 5 0 0 *Up-Regulation|*Ethanol|Snail Family Transcription Factors|Epithelial-Mesenchymal Transition|Cell Movement|Transforming Growth Factor beta|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Signal Transduction|Colorectal Neoplasms|Cell Proliferation|Cell Line, Tumor|*Cytoplasm|*Colonic Neoplasms 1468 neurophysin 31593833 Pregnancy Hypertens 2019 10.1016/j.preghy.2019.09.017 0 0 0 0 Pregnancy|Humans|Female|*Pre-Eclampsia|*Arginine Vasopressin|AVP protein, human|*Neurophysins|*Vasopressins|*Promoter Regions, Genetic|*Protein Precursors|Gene Frequency|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Polymorphism, Restriction Fragment Length|Genotype|Case-Control Studies 1468 neurophysin 31588537 Exp Suppl 2019 10.1007/978-3-030-25905-1_14 0 0 0 0 Humans|Mice|Animals|*Diabetes Insipidus, Neurogenic|Neurodegenerative Diseases|AVP protein, human|Neurophysin II|Vasopressin|Protein Precursors|Arginine Vasopressin|DDAVP|Pedigree|Mutations|Carrier Proteins|Endoplasmic Reticulum|Diabetes Mellitus 1468 neurophysin 31395885 Nat Rev Dis Primers 2019 10.1038/s41572-019-0103-2 2 0 0 0 Humans|Child|Dipsogenic Diabetes Insipidus|*Diabetes Insipidus|Polydipsia|AVP protein, human|Neurophysins|Central Diabetes Insipidus|Primary Polydipsia|Polyuria|Vasopressins|Diabetes Insipidus, Nephrogenic|Water Deprivation|Arginine Vasopressin|Protein Precursors|Glycopeptides|Saline Solution, Hypertonic|Osmolar Concentration|Syndrome|Diagnosis, Differential 1468 neurophysin 31395386 Methods Cell Biol. 2019 10.1016/bs.mcb.2019.05.008 1 0 0 0 Humans|Dogs|Animals|*Polycystic Kidney, Autosomal Dominant|polycystic kidney disease 1 protein|TRPP Cation Channels|Kidneys|Tolvaptan|Cells, Cultured|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Cell Line|Cysts|Cyclic AMP|Cell Proliferation|AVP protein, human|Vasopressins|Cell Division|Madin Darby Canine Kidney Cells|Neurophysins 1468 neurophysin 31339235 Brain Behav 2019 PMC6749484 10.1002/brb3.1355 1 0 0 0 Humans|*mRNA|AVP protein, human|*Neurophysins|*Vasopressin|*Hypothalamus|Supraoptic Nucleus|*Protein Precursors|Paraventricular Hypothalamic Nucleus|Arginine Vasopressin|Oxytocin|In Situ Hybridization|*Schizophrenia 1468 neurophysin 31327049 Diabetologia 2019 PMC6805798 10.1007/s00125-019-4953-7 1 0 0 0 Animals|*Vasoactive Intestinal Peptide|*Arginine Vasopressin|*Diabetes Mellitus, Type 2|*Suprachiasmatic Nucleus|*Neurons|*Cells, Glial|AVP protein, human|*Neurophysins|*Vasopressins|Circadian Rhythm|Suprachiasmatic Nucleus Neurons 1468 neurophysin 31316622 Exp Ther Med 2019 PMC6601387 10.3892/etm.2019.7645 0 0 0 0 Adult|Humans|AVP protein, human|*Neurophysin II|*Diabetes Insipidus, Neurogenic|*Codon, Nonsense|Vasopressin|Diabetes Insipidus|Pedigree|Exon|Mutations|Base Sequence|Arginine Vasopressin|Pituitary Gland, Posterior|Mutation, Missense|Protein Precursors|Chinese|Diabetes Mellitus 1468 neurophysin 31312322 Pan Afr Med J 2019 PMC6620088 10.11604/pamj.2019.32.210.6006 0 2 0 0 Humans|Nephrogenic Syndrome of Inappropriate Antidiuresis|*Inappropriate ADH Syndrome|*Genetic Diseases, X-Linked|Diabetes Insipidus, Nephrogenic|V2 Receptor|AVP protein, human|Vasopressins|Mutations|Water-Electrolyte Imbalance|Water-Electrolyte Balance|Mutations, Activation|Neurophysins 1468 neurophysin 31238300 Eur. 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Allergy Clin. Immunol. 2019 10.1016/j.jaci.2019.09.029 0 0 0 373 secukinumab|IL17A protein, human|IL-17A|*Antibodies, Monoclonal|Psoriasis|I-kappa B Proteins|Keratinocytes|Nuclear Proteins|Tumor Necrosis Factor-alpha|*Dermatologic Agents 148 NFKBIZ 31577850 J Pathol Clin Res 2019 PMC6966707 10.1002/cjp2.147 0 0 0 373 Humans|Tumor Necrosis Factor-alpha|*Psoriasis|Adalimumab|Hidradenitis Suppurativa|Antibodies, Monoclonal|Crohn Disease|Antibodies, Monoclonal, Humanized|Keratinocytes|Plasmacytoid Dendritic Cells|T-Lymphocytes|ERAP1 protein, human|Aminopeptidases|Minor Histocompatibility Antigens 148 NFKBIZ 31477014 Genet. Sel. Evol. 2019 PMC6721172 10.1186/s12711-019-0490-6 1 0 0 373 Swine|Animals|*Genome|Genome-Wide Association Study|Animal Feed|Phenotype|Breeding|Single Nucleotide Polymorphism|Genotype|*Gene Expression 148 NFKBIZ 31356171 Immunohorizons 2019 10.4049/immunohorizons.1900023 1 3 0 373 Humans|Mice|Animals|IL17A protein, human|*Interleukin-17|*TYK2 Kinase|STAT3 protein, human|*Transcription Factor, STAT3|Psoriasis|Keratinocytes|*Gene Expression Regulation|Signal Transduction|Imiquimod|Janus Kinases|Skin|Cytokines|Inflammation|Dermatitis|mRNA|Epidermis|Nuclear Proteins 148 NFKBIZ 31267486 Mol Diagn Ther 2019 10.1007/s40291-019-00409-x 0 1 0 373 *Adalimumab|Tumor Necrosis Factor-alpha|*Psoriasis|NFKBIZ protein, human|*I-kappa B Proteins|HLA-C Antigens|*Nuclear Proteins|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide 148 NFKBIZ 31164412 Mol. Cancer Res. 2019 PMC6720116 10.1158/1541-7786.MCR-19-0227 0 0 0 373 *Myeloid Differentiation Factor 88|*ras Oncogenes|*Adaptor Proteins, Signal Transducing|Keratinocytes|Cell Transformation, Neoplastic|*Apoptosis|NF-kappa B|9,10-Dimethyl-1,2-benzanthracene|Skin Neoplasms|Tetradecanoylphorbol Acetate|ras Proteins|Signal Transduction|T-Lymphocytes|Tumor Microenvironment 148 NFKBIZ 31156649 Front Immunol 2019 PMC6532024 10.3389/fimmu.2019.01107 1 0 0 373 Tifab protein, human|*TNF Receptor-Associated Factor 6|*Cells, Epithelial|Signal Transduction|NF-kappa B|Psoriasis|RELA protein, human|Transcription Factor RelA|Interleukin-17|Skin|Inflammation|Cytokines|Ubiquitin Ligase E3|Tissues, Epithelial 148 NFKBIZ 30902734 Immunol. 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Cell Biol. 2019 10.1038/s41556-019-0416-0 2 0 0 98 Humans|*RNA, Double-Stranded|DEAD Box Protein 58|RNA, Viral|Immunity, Innate|Signal Transduction|DEAD-box RNA Helicases|Interferon Type I|Interferon-beta|Vesiculovirus|RNA Viruses|Adaptor Proteins, Signal Transducing|Virus Infection, RNA|HEK293 Cells|Virus Infection|Antiviral Agents|Mitochondria 45 NFX1 31517622 Endocr Regul 2019 10.2478/enr-2019-0009 0 0 0 98 Humans|Adolescent|*Insulin Resistance|B-insulin|*Insulin|Pediatric Obesity|Gene Expression Regulation|*Biotin 45 NFX1 31401562 J Neurointerv Surg 2019 PMC7014815 10.1136/neurintsurg-2019-014900 0 0 0 98 *Exome|*Whole Exome Sequencing|Pedigree|Intracranial Aneurysms|Genetic Predisposition to Disease|Heterozygote 45 NFX1 31059266 J. Proteome Res. 2019 10.1021/acs.jproteome.9b00139 3 3 0 98 Humans|*Proteomics|HeLa Cells|Ubiquitination|Ubiquitin|Ubiquitin Thiolesterase|Proteasome|Cell Line, Tumor|Cell Proliferation|Proteolysis|RNA Interference|mRNA|Apoptosis|NFX1 protein, human|Repressor Proteins|USP9X protein, human 45 NFX1 30903928 Virology 2019 PMC6486444 10.1016/j.virol.2019.03.008 1 6 0 98 Humans|Male|*Keratinocytes|*Papillomavirus Infections|*MAP Kinase Signaling System|E6 protein, Human papillomavirus type 16|*Oncogene Proteins, Viral|*Repressor Proteins|Human papillomavirus 16|*Cell Differentiation|Foreskin|Signal Transduction|Telomerase|Cells, Cultured|Phosphorylation|*Organogenesis|NFX1 protein, human 45 NFX1 30776478 Cancer Lett. 2019 PMC6433130 10.1016/j.canlet.2019.02.024 2 5 0 98 Humans|Female|*Telomerase|*Uterine Cervical Neoplasms|*Papillomavirus Infections|E6 protein, Human papillomavirus type 16|*Oncogene Proteins, Viral|*Repressor Proteins|Human papillomavirus 16|Upregulation|Keratinocytes|Cell Lines|RNA, Messenger|Cells, Cultured|Cell Proliferation|NFX1 protein, human 45 NHLH1 31442438 Gastroenterology 2019 10.1053/j.gastro.2019.08.019 0 1 0 132 Mice|Humans|Animals|*Neural Crest|*Hedgehog Proteins|Enteric Nervous System|*Signal Transduction|Cell Differentiation|*Intestine, Small|Pluripotent Stem Cells|*Transcriptome|Nerve Tissue Proteins|Transcription Factors|Neurons|*Single-Cell Analyses|Gene Expression Profiling 43 NINJ1 31526566 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.09.007 1 3 0 93 *Nerve Regeneration|Schwann Cells|Peripheral Nerve Injury|Sciatic Nerve|*Neurogenesis|Pericytes|Cell Adhesion Molecules, Neuronal|Coculture Techniques 71 NINJ1 31108272 Leg Med (Tokyo) 2019 10.1016/j.legalmed.2019.04.008 0 0 0 93 71 NINJ1 31091274 PLoS ONE 2019 PMC6519837 10.1371/journal.pone.0216987 0 1 0 93 71 NINJ1 30805011 Stem Cells Int 2019 PMC6362508 10.1155/2019/7274057 0 0 0 93 71 NINJ1 30700695 Exp. Mol. Med. 2019 PMC6353902 10.1038/s12276-018-0201-3 2 32 0 93 71 NINJ1 30621923 J Sex Med 2019 10.1016/j.jsxm.2018.11.010 0 2 0 93 Rats|Male|Animals|Humans|*Prostate|Penile Erection|*Hypogastric Plexus|Erectile Dysfunction|Penis|Rats, Sprague-Dawley|Nerve Regeneration|Nitric Oxide Synthase Type I|Recovery of Function|Disease Models, Animal|*Ganglia, Sympathetic|Neurons 71 NLRP5 31829238 Clin Epigenetics 2019 PMC6907351 10.1186/s13148-019-0760-8 1 0 0 64 Humans|*Maternal Effect|Beckwith-Wiedemann Syndrome|Silver-Russell Syndrome|Genomic Imprinting|*Phenotype|DNA Methylation|*Variations, Phenotypic|Pedigree|Germ Line 65 NLRP5 31575650 Development 2019 10.1242/dev.183616 2 0 0 64 Mice|Animals|*Cytoplasm|Oocytes|Embryonic Development|Embryo, Mammalian|Gene Expression Regulation, Developmental|RNA-Binding Proteins|*Cytosol|RNA, Messenger|Protein-Arginine Deiminases|*Organelle 65 NLRP5 31273585 J. Assist. Reprod. Genet. 2019 PMC6707996 10.1007/s10815-019-01499-6 1 0 0 64 Pregnancy|Female|Humans|*Genes, Essential|*Exome|*Whole Exome Sequencing|Abortion, Habitual|DNA Copy Number Variations|Genetic Predisposition to Disease|Mutation|Aneuploid 65 NLRP5 31201414 Biol. Reprod. 2019 10.1093/biolre/ioz098 4 0 0 64 Humans|Pregnancy|Female|Infant, Newborn|Mice|Animals|*Pyrin Domain|*Oocytes|*Embryo Development|Preimplantation Embryos|Moles, Hydatidiform|Adaptor Proteins, Signal Transducing|Reproduction|Gene Expression Regulation, Developmental|Fertility|Genes, Regulator|Mutations|Cytoplasm|NLR Proteins|Tle6 protein, human|Transcription Factors|Nlrp2 protein, mouse|Proteins|Ooep protein, mouse 65 NLRP5 30877238 J. Med. Genet. 2019 10.1136/jmedgenet-2018-105936 6 0 0 64 Pregnancy|Humans|Male|Female|*Mutations|Embryonic Development|Infertility, Female|Oocytes 65 NNAT 31871428 Mediators Inflamm. 2019 PMC6906841 10.1155/2019/5618023 0 0 0 165 Humans|Mice|Animals|3T3-L1 Cells|CCL2 protein, human|Monocyte Chemoattractant Protein-1|Adiponectin|Adipocytes|Tumor Necrosis Factor-alpha|NF-kappa B|PPAR gamma|Cell Differentiation|Interleukin-6|Signal Transduction 168 NNAT 31805566 Cells Tissues Organs (Print) 2019 10.1159/000504359 0 0 0 165 Mice|Pregnancy|Female|Rats|Animals|Nerve Tissue Proteins|*Neurogenesis|Membrane Proteins|Cell Differentiation|Gene Expression Regulation|Transcription Factor|*Biological Phenomena|Brain 168 NNAT 31231645 Front Cell Dev Biol 2019 PMC6558402 10.3389/fcell.2019.00082 0 0 0 165 Humans|Hedgehog Proteins|*Astrocytes|*Neurons|Signal Transduction|Neural Stem Cells|Neurogenesis|Cell Differentiation|Neuroglia|*Transcriptome Analysis|Cellular Reprogramming|Fetus 168 NNAT 31165373 Breast Cancer Res. Treat. 2019 10.1007/s10549-019-05307-8 0 0 0 165 *Incidence|Prognosis|Receptors, Estrogen|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Gene Expression Profiling|Cell Line, Tumor|Nerve Tissue Proteins|Estrogens 168 NNAT 31098764 Brain Struct Funct 2019 10.1007/s00429-019-01883-z 6 0 0 165 Mice|Animals|*GABAergic Neurons|*Vasoactive Intestinal Peptide|*Transcriptome|Interneurons|*Subiculum|Cells, Pyramidal|Dendrites|Presynaptic Terminals|preproenkephalin|Enkephalins|gamma-Aminobutyric Acid|Muscarinic Receptor|Acetylcholine|proenkephalin|Protein Precursors|Pcp4 protein, mouse|Nerve Tissue Proteins 168 NNAT 30933048 Psychiatr. Genet. 2019 10.1097/YPG.0000000000000224 1 0 0 165 Humans|Male|*Anorexia Nervosa|Genetic Predisposition to Disease 168 NNAT 30930126 Mol Metab 2019 PMC6531841 10.1016/j.molmet.2019.03.006 4 2 0 165 Humans|*Point Mutation|*Transcriptional Activation|*Cell Differentiation|Homeodomain Proteins|Insulin-Secreting Cells|Trans-Activators|Insulin|Diabetes Mellitus, Type 2|Cells, Cultured 168 NNAT 30869556 J. Histochem. Cytochem. 2019 PMC6598131 10.1369/0022155419836433 0 0 0 165 Rats|Animals|Male|*Hair Follicle|*Testis|*Tongue|Nerve Tissue Proteins|Membrane Proteins|*Pancreas|*Tongue Diseases 168 NNAT 30672333 Epigenomics 2019 10.2217/epi-2018-0060 0 0 0 165 Genomic Imprinting|*Regulatory Sequences, Nucleic Acid|CpG Islands|Nerve Tissue Proteins|DNA Methylation|Membrane Proteins|Intron 168 NOBOX 31704792 Development 2019 PMC6918767 10.1242/dev.176701 2 0 0 47 Animals|Female|Humans|Infant, Newborn|Oocytes|Oogenesis|Ovarian Follicle|Ovary|Granulosa Cells|*SUMO-Conjugations|Meiosis|Transcription Factors|Homeobox Gene|Gene Expression Regulation, Developmental|Fertility 103 NOBOX 31310068 Int J Fertil Steril 2019 PMC6642427 10.22074/ijfs.2019.5599 0 0 0 47 Humans|Female|*Primary Ovarian Insufficiency|Genome-Wide Association Study|*Menopause, Premature|Genetic Screening|Genetic Predisposition to Disease|Mutation|Chromosomal Abnormalities 103 NOBOX 31293321 J Hum Reprod Sci 2019 PMC6594122 10.4103/jhrs.JHRS_112_18 0 0 0 47 Humans|Female|Infant, Newborn|*Genes, Homeobox|*Ovary|*Infertility, Female|Homeodomain Proteins|Primary Ovarian Insufficiency|Transcription Factors|Genetic Predisposition to Disease 103 NOBOX 31250783 Zygote 2019 10.1017/S0967199419000017 0 0 0 47 Animals|Female|Xenopus Proteins|Xenopus|Xenopus laevis|Oocytes|Transcription Factors|Promoter Regions, Genetic|Regulatory Regions|Base Sequence|Animals, Genetically Modified|Nuclear Proteins|Gene Expression Regulation|Luciferase 103 NOBOX 31026518 J Gynecol Obstet Hum Reprod 2019 10.1016/j.jogoh.2019.04.007 0 0 0 47 Humans|Female|Adult|Turkey|*Primary Ovarian Insufficiency|*Menopause, Premature|Fragile X Mental Retardation Protein|Trinucleotide Repeat Expansion|Alleles|Ovarian Follicle|Mutation 103 NOBOX 30770786 Cell Death Dis 2019 PMC6377673 10.1038/s41419-018-1208-3 1 0 0 47 Female|Pregnancy|Mice|Animals|*Ovarian Follicle|*Oocyte|Ovary|CDH1 protein, human|*E Cadherin|Transcription Factors|Homeodomain Proteins|Homeobox|Gene Expression Regulation, Developmental|Apoptosis|Animals, Newborn|Antigens, CD 103 nos1ap 31747862 J Am Heart Assoc 2019 PMC6912973 10.1161/JAHA.119.013751 1 0 0 240 Humans|Female|Male|United States|*Sudden Cardiac Death|Long QT Syndrome|Electrocardiography|Arrhythmias, Cardiac|Coronary Artery Disease|Single Nucleotide Polymorphism|Genotype|Risk Factors|Logistic Regression|Finland 183 nos1ap 31473185 EBioMedicine 2019 PMC6796549 10.1016/j.ebiom.2019.08.033 0 1 0 240 Mice|Animals|*Mice, Obese|*Insulin Resistance|Diabetes Mellitus, Type 2|*Liver|Fatty Liver|Diet, High-Fat|*Homeostasis|Insulin|Obesity|Glucose|Adaptor Proteins, Signal Transducing|Signal Transduction|Nitric Oxide Synthase 183 nos1ap 31447468 Int Heart J 2019 10.1536/ihj.19-024 0 0 0 240 Humans|Female|Genotype|Sudden Cardiac Death|Long QT Syndrome|Allele|Polymorphism, Single Nucleotide|Asian|Electrocardiography|European Continental Ancestry Group|Adaptor Proteins, Signal Transducing|Risk Factors|NOS1AP protein, human 183 nos1ap 31398660 Stem Cell Res 2019 10.1016/j.scr.2019.101510 0 0 0 240 Humans|*Induced Pluripotent Stem Cells|Romano-Ward Syndrome|KCNQ1 Potassium Channel|Heterozygote|Mutation|Phenotype|Cell Line|Adaptor Proteins, Signal Transducing|Cell Differentiation|*African Continental Ancestry Group 183 nos1ap 31171914 Int J Med Sci 2019 PMC6535660 10.7150/ijms.31579 1 4 0 240 183 nos1ap 31160584 Nat Commun 2019 PMC6546774 10.1038/s41467-019-10278-x 4 10 0 240 Mice|Animals|tau Proteins|Tauopathy|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|Alzheimer Disease|Mice, Transgenic|NOS1 protein, human|Neuronal Nitric Oxide Synthase|Maze Learning|Hippocampus|Disease Models, Animal|*Protein Binding|Receptors, N-Methyl-D-Aspartate 183 nos1ap 31151238 Animals (Basel) 2019 PMC6617538 10.3390/ani9060296 2 0 0 240 Humans|Cattle|Animals|Phenotypes|Breeding|SNPs|Genotype|Genome-Wide Association Study|Quantitative Trait Loci|Haplotype|Traits, Complex|*Chinese|Genomics 183 nos1ap 31121060 J. Neuroendocrinol. 2019 PMC6771480 10.1111/jne.12735 3 2 0 240 Animals|Mice|NR3C2 protein, human|*Receptors, Mineralocorticoid|Receptors, Glucocorticoid|Corticosterone|Hippocampus|tacrolimus binding protein 5|Tacrolimus Binding Proteins|Glucocorticoid|Gene Expression Regulation|mRNA|Stress, Physiological|Transcriptional Activation|Brain|Up-Regulation|Downregulation 183 nos1ap 30878014 Stem Cell Res 2019 10.1016/j.scr.2019.101416 0 0 0 240 Humans|*Romano-Ward Syndrome|*Induced Pluripotent Stem Cells|KCNQ1 Potassium Channel|Cardiomyocytes|Heterozygote|Cell Differentiation|Cell Line|Mutation|NOS1AP protein, human|Adaptor Proteins, Signal Transducing 183 nos1ap 30727847 Stroke 2019 10.1161/STROKEAHA.118.022647 0 1 0 240 Rats|Mice|Animals|*Post-Synaptic Density|NOS1 protein, human|*Nitric Oxide Synthase Type I|*Disks Large Homolog 4 Protein|*Stroke|*Recovery of Function|*Neuroplasticity|Rats, Sprague-Dawley|Adaptor Proteins, Signal Transducing|Nitric Oxide 183 NOVA1 31816601 Aging (Albany NY) 2019 PMC6932873 10.18632/aging.102571 2 0 0 155 *Alzheimer Disease|Phosphatidylinositol 3-Kinases|*Autophagy|Beclin 1|Module, Gene|NOVA1 protein, human|RNA-Binding Proteins|Gene Expression Profiling|Signal Transduction 87 NOVA1 31599400 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201909_18984 0 2 0 155 *miRNA|*Diabetic Retinopathy|NOVA1 protein, human|*RNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Up-Regulation|Cell Line, Tumor|*Protective Agents|Diabetes Mellitus 87 NOVA1 31568004 Medicine (Baltimore) 2019 PMC6756728 10.1097/MD.0000000000017267 0 0 0 155 Humans|*Computational Biology|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|SRPUL protein, human|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|MicroRNAs|mRNA|Databases, Genetic|Biomarkers, Tumor|Genes, Regulator|Cluster Analysis|*Epithelium|Membrane Proteins|*Smoking|MUCL1 protein, human 87 NOVA1 31541909 Surg Oncol 2019 10.1016/j.suronc.2019.09.009 3 3 0 155 Humans|Nova antigen|*Interleukin-6|Neoplasm Recurrence, Local|JAK2 protein, human|*Janus Kinase 2|*Colorectal Cancer|STAT3 protein, human|STAT3 Transcription Factor|*RNA Binding Protein|*Nerve Tissue Proteins|*Signal Transduction|NOVA1 protein, human|Cell Proliferation|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Prognosis|Cell Movement|Biomarkers, Tumor 87 NOVA1 31524231 Int. 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Med. 2019 10.3892/ijmm.2019.4278 2 3 0 155 Humans|*RNA, Long Noncoding|*Downregulation|*Thyroid Cancer|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Apoptosis|Lymphatic Metastasis|Xenograft Model Antitumor Assays|Disease Progression|*Phenotypes|NOVA1 protein, human|RNA-Binding Proteins|MIRN592 microRNA, human 87 NOVA1 31427386 Genome Res. 2019 PMC6724681 10.1101/gr.242636.118 3 0 0 155 Mice|Animals|*RNA Precursors|*RNA Splicing|Editing, RNA|NOVA1 protein, human|RNA-Binding Proteins|Adenosine Deaminase|Inosine|NOVA2 protein, human|Exons|Introns|Alternative Splicing|RNA, Messenger|Adenosine|Nucleic Acid Conformation|Nerve Tissue Proteins|Nova2 protein, mouse|Antigens, Neoplasm|ADAR1 protein, mouse 87 NOVA1 31382054 Biochim Biophys Acta Gene Regul Mech 2019 10.1016/j.bbagrm.2019.194413 1 4 0 155 Humans|Human Induced Pluripotent Stem Cells|*RNA Splicing|NOVA1 protein, human|*RNA Binding Protein|*DNA-Binding Proteins|Alternative Splicing|Exon|Protein Isoforms|Amyotrophic Lateral Sclerosis|RNA, Messenger|Frontotemporal Dementia|Cell Line|Neurons|*Schizophrenia|TDP-43 protein, human 87 NOVA1 31375778 Sci Rep 2019 PMC6677744 10.1038/s41598-019-47755-8 0 0 0 155 Humans|*Squamous Cell Carcinoma of Head and Neck|Nova antigen|*Epigenesis, Genetic|*RNA-Binding Proteins|NOVA1 protein, human|*Nerve Tissue Proteins|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Tumor Microenvironment|Cells, Stromal|Biomarkers, Tumor|Cell Line, Tumor|*Inflammation|Immunohistochemistry 87 NOVA1 31310629 PLoS ONE 2019 PMC6634788 10.1371/journal.pone.0218989 1 0 0 155 Humans|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Prognosis|Carcinoma, Squamous Cell|Cancer, Tongue|Papillomavirus Infections|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|EPS8 protein, human|Adaptor Proteins, Signal Transducing|FNDC1 protein, human|Neoplasm Proteins|UBE2Q1 protein, human|Ubiquitin-Conjugating Enzymes|SLC4A1AP protein, human|Antiporters 87 NOVA1 31298381 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201906_18196 1 6 0 155 Long Non-Coding RNA|*Disease Progression|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor 87 NOVA1 31212673 Medicina (Kaunas) 2019 PMC6631768 10.3390/medicina55060269 0 0 0 155 87 NOVA1 31115560 Oncol. Rep. 2019 10.3892/or.2019.7160 5 1 0 155 Animals|Mice|*Multiple Myeloma|*SCID Mice|RNA, Micro|Cell Proliferation|Apoptosis|Gene Expression Regulation, Neoplastic|Upregulation|Cell Cycle|Down-Regulation|Cell Line, Tumor|mirn181 microRNA, mouse 87 NOVA1 30962495 Sci Rep 2019 PMC6453917 10.1038/s41598-019-42289-5 3 0 0 155 *Synthetic Resin|*Enkephalin|DPDPE|Receptors, Opioid, delta|Receptors, Opioid, mu|Receptors, Opioid|*Potential, Action|Structure-Activity Relationship|Amino Acid Sequence|Brain 87 NOVA1 30696738 mBio 2019 PMC6355981 10.1128/mBio.02687-18 13 8 0 155 Humans|Female|*Human Papilloma Virus|*Papillomavirus Infections|HPV 16|Papillomavirus E7 Proteins|Oncogene Proteins, Viral|Human papillomavirus 18|Cervical Cancer|NOVA1 protein, human|*RNA-Binding Proteins|Repressor Proteins|DNA-Binding Proteins|Transcriptome Analyses|RNA, Messenger|Carcinogenesis|Cell Line, Tumor|Keratinocytes|DNA Replication|KHSRP protein, human 87 NPAS1 31848352 Nat Commun 2019 PMC6917767 10.1038/s41467-019-13641-0 0 0 0 55 *Nucleosomes|H2AX protein, human|*Histones|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|Chromatin|Poly ADP Ribose Polymerase|DNA Breaks, Double-Stranded|Poly ADP Ribosylation|DNA|DNA Repair|DNA Damage|*Catalysis 35 NPAS1 31811030 J. Neurosci. 2019 PMC6975296 10.1523/JNEUROSCI.1199-19.2019 2 1 0 55 Globus Pallidus|Action Potentials|Neurons|Neural Pathways|Basal Ganglia 35 NPAS1 31381576 PLoS Genet. 2019 PMC6695205 10.1371/journal.pgen.1007980 2 0 0 55 Animals|*Presynaptic Terminals|Neuromuscular Junctions|Drosophila|Drosophila Proteins|*Glia|*Signal Transduction|Synaptic Transmission|Animals, Genetically Modified|Transcription Factors|Larvae|*Hypoxia|Microtubule 35 NPAS1 31139206 Front Genet 2019 PMC6527781 10.3389/fgene.2019.00412 1 0 0 55 Cattle|Female|Animals|*Genome-Wide Association Study|Dairying|Lactation|Milk|Quantitative Trait, Heritable|Phenotypes|Fertility|Genome|Genotype|Polymorphism, Single Nucleotide|Genomics 35 Npas3 31381576 PLoS Genet. 2019 PMC6695205 10.1371/journal.pgen.1007980 2 0 0 39 Animals|*Presynaptic Terminals|Neuromuscular Junctions|Drosophila|Drosophila Proteins|*Glia|*Signal Transduction|Synaptic Transmission|Animals, Genetically Modified|Transcription Factors|Larvae|*Hypoxia|Microtubule 56 npas4 31883511 BMC Neurosci 2019 PMC6935488 10.1186/s12868-019-0546-0 0 0 0 180 histone deacetylase 3|*Histone Deacetylases|BDNF protein, human|*BDNF|*Gene Expression|Neurons|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Cells, Cultured 169 npas4 31852685 Development 2019 10.1242/dev.181040 0 0 0 180 Animals|*Junctional Adhesion Molecule|Endothelial Cells|Zebrafish|Zebrafish Proteins|Hematopoietic Stem Cells|Hematopoiesis|T-Cell Acute Lymphocytic Leukemia Protein 1|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Mesoderm|Proto-Oncogene Proteins|Endothelium|Hematopoietic Stem Cell Transplantation 169 npas4 31801086 Cell Rep 2019 10.1016/j.celrep.2019.10.116 0 8 0 180 *Phosphorylation|Proteomics|DRD1 protein, human|Dopamine D1 Receptor|*Reward|Nucleus Accumbens|*Mitogen-Activated Protein Kinases|*Neurons|Dopamine|Protein Kinase A|Cocaine|ARNT protein, human|*Aryl Hydrocarbon Receptor Nuclear Translocator|Signal Transduction|BDNF protein, human|Brain-Derived Neurotrophic Factor|*Gene Expression|Neurites 169 npas4 31784582 Sci Rep 2019 PMC6884539 10.1038/s41598-019-52924-w 0 1 0 180 Humans|*Uric Acid|Genome-Wide Association Study|*Indians, North American|Single Nucleotide Polymorphisms|ATP Binding Cassette Transporter, Subfamily G, Member 2|Hyperuricemia|Gout|Genetic Predisposition to Disease|Glucose Transport Proteins, Facilitative|Genotype|Allele Frequency|ATP-Binding Cassette Transporters|Cohort Studies|Neoplasm Proteins 169 npas4 31751544 Neuron 2019 10.1016/j.neuron.2019.10.022 0 0 0 180 *Activation, Transcription|Neurons|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation|*Transcription Factors|*Biophysical Phenomena 169 npas4 31629107 Cytokine 2019 10.1016/j.cyto.2019.154879 1 5 0 180 Male|Female|Humans|Animals|Mice|*Lipopolysaccharides|Chromosome 15q13.3 Microdeletion Syndrome|*Chromosome Disorders|*Chromosome Deletion|*Seizures|*Intellectual Disability|IL1B protein, human|Interleukin-1beta|*Chromosomes, Human, Pair 15|Cytokines|Tumor Necrosis Factor-alpha|*Disease Models, Animal|Gene Expression Regulation|Fan1 protein, mouse|Endodeoxyribonucleases 169 npas4 31619230 BMC Med Genomics 2019 PMC6796419 10.1186/s12920-019-0581-9 2 0 0 180 Humans|*Huntington Disease|*Caudate Nucleus|*Brain|Corpus Striatum|Gene Expression|Gene Expression Profiling|Cerebral Cortex 169 npas4 31585079 Cell 2019 PMC6800120 10.1016/j.cell.2019.09.004 3 0 0 180 Mice|Animals|*Neurons|Hippocampus|Excitatory Postsynaptic Potentials|Synapses|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation|Action Potentials|*Genomics|Npas4 protein, mouse 169 NPAT 31806526 Schizophr. 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Biol. 2019 10.1007/978-1-4939-8873-0_33 0 0 0 187 *Macroautophagy|Autophagosomes|Autophagy|Intravital Microscopy|Microtubule-Associated Proteins|Microscopy, Fluorescence|*Brain|Green Fluorescent Proteins|Neurons 121 NPTX1 31606623 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109497 3 3 0 493 *Carcinoma, Hepatocellular|*Liver Neoplasms|MicroRNAs|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Proliferation|Tumorigenesis|Hep G2 Cells|Cell Line, Tumor|Cell Movement|RNAs, Circular 39 NPTX1 31455042 Cancers (Basel) 2019 PMC6769884 10.3390/cancers11091251 2 0 0 493 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Transcriptome|CXCL8 protein, human|*Interleukin-8|*Pectoralis Muscles|Neoplasm Recurrence, Local|Cachexia|Prognosis|Muscle Atrophy|Transcriptome Analysis|Muscle, Skeletal|Tomography, X-Ray Computed|Myotubes|Cell Line, Tumor|Biomarkers|Cell Differentiation 39 NPTX1 31452262 J. Cell. Biochem. 2019 10.1002/jcb.29332 0 4 0 493 Humans|*RNA, Long Noncoding|*mRNA|*Stomach Neoplasms|Phosphatidylinositol 3-Kinases|MIRN204 microRNA, human|*RNA, Micro|Gene Expression Regulation, Neoplastic|Prognosis|Gene Regulatory Networks|Downregulation|Signal Transduction|Cell Proliferation|Biomarkers, Tumor|Oncogenesis|CHRDL1 protein, human|Eye Proteins|Nerve Tissue Proteins 39 NPTX1 31175513 Mol. Biol. Rep. 2019 10.1007/s11033-019-04904-6 0 0 0 493 Pregnancy|Female|Animals|*Litter Size|*Goats|*Sequencing, Whole Genome|Genome|Breeding|Fertility|Genotype|Polymorphism, Single Nucleotide 39 NPTX1 31118494 Genes Immun. 2019 10.1038/s41435-019-0081-0 1 5 0 493 Humans|*Squamous Cell Carcinoma of Head and Neck|*Cell Proliferation|MicroRNAs|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Epithelial-Mesenchymal Transition|Cell Line, Tumor|MIRN4295 microRNA, human 39 NPTX1 31113871 Biosci. Rep. 2019 PMC6549097 10.1042/BSR20181662 0 3 0 493 Humans|*Carcinoma, Hepatocellular|*Proto-Oncogene Proteins c-akt|*Liver Neoplasms|*Apoptosis|Signal Transduction|Phosphatidylinositol 3-Kinases|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|Cell Movement|Prognosis|Phosphorylation 39 NPTX1 31043800 Cancer Manag Res 2019 PMC6472287 10.2147/CMAR.S196509 2 5 0 493 *Stomach Neoplasms|*Signal Transduction|Neoplasm Invasiveness|Prognosis|Cell Movement|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Integrins 39 NPTX1 30906475 Exp Ther Med 2019 PMC6425241 10.3892/etm.2019.7284 6 10 0 493 Humans|*RNA, Micro|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Phosphoinositide 3 Kinase|*Insulin Receptor Substrate Proteins|*Glioma|*Cell Proliferation|*Signal Transduction|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Line, Tumor|*Cell Differentiation|neuronal pentraxin|Nerve Tissue Proteins|C-Reactive Protein|MIRN128 microRNA, human 39 NPTX1 30841487 J Clin Med 2019 PMC6462954 10.3390/jcm8030308 4 0 0 493 nintedanib|*Computational Biology|*Idiopathic Pulmonary Fibrosis|*Indoles|*Sequencing, Next-Generation|*Fibroblasts|miRNA|Gene Expression Regulation|mRNA|Myofibroblasts|*Gene Expression|Cell Proliferation|Protein Kinase Inhibitors|Upregulation|*Biochemical Phenomena 39 NPTX1 30713215 Genes Genet. Syst. 2019 10.1266/ggs.18-00036 2 0 0 493 Female|Rats|Animals|*Oxidopamine|*Transcriptome|*Parkinson Disease|*Rats, Wistar|RNA, Long Noncoding|MicroRNAs|mRNA|Gene Regulatory Networks|Protein Interaction Maps|Downregulation|Gene Ontology|*Whole Exome Sequencing|Up-Regulation|RIG-I protein, rat|RNA Helicases 39 NPTX2 31853477 Alzheimers Dement (N Y) 2019 PMC6911971 10.1016/j.trci.2019.11.002 0 0 0 198 *Alzheimer Disease|Amyloid beta-Peptides|tau Proteins|*Biomarkers|Cognitive Dysfunction|*Disease Progression|Neuropsychological Tests|*Cognition|Diagnosis, Differential 84 NPTX2 31836174 Biol. Psychiatry 2019 10.1016/j.biopsych.2019.10.009 0 0 0 198 Humans|*Cocaine|*Memory|*Hippocampus|Dopamine Uptake Inhibitors|Extinction, Psychological|Cocaine-Related Disorders|Conditioning, Psychological|Receptors, AMPA|Spatial Behavior 84 NPTX2 31832114 EPMA J 2019 PMC6882982 10.1007/s13167-019-00187-w 1 0 0 198 Humans|*Pituitary Neoplasms|*Proteomics|*Follicle Stimulating Hormone|*Prognosis|Adenoma 84 NPTX2 31772567 Neural Plast. 2019 PMC6854953 10.1155/2019/6804575 0 1 0 198 neuronal pentraxin|*Extracellular Matrix|Nerve Tissue Proteins|Neurons|Proteoglycan|Neuronal Plasticity|Extracellular Matrix Proteins|Synapses|Chondroitin Sulfates|*Biophysical Phenomena|Hyaluronan 84 NPTX2 31701992 Food Funct 2019 10.1039/c9fo01387c 0 0 0 198 Rats|Animals|*Soybean Proteins|*Caseins|*Rats, Zucker|*Liver Steatosis|*Liver|*Obesity|*Diet|*Gene Expression|Polymerase Chain Reaction 84 NPTX2 31498486 J. Cell. 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Neurosci. 2019 PMC6607753 10.1523/JNEUROSCI.0015-19.2019 0 2 0 198 Male|Mice|Animals|*Cocaine|*Nucleus Accumbens|Cocaine-Related Disorders|Drug-Seeking Behavior|*Self Administration|Histone|Nucleosomes|Epigenesis, Genetic 84 NPTX2 30962417 Cell Death Dis 2019 PMC6453902 10.1038/s41419-019-1522-4 0 2 0 198 Mice|Animals|*Microglia|*Signal Transduction|*Hippocampus|NF-kappa B|Tumor Necrosis Factor-alpha|MicroRNAs|*Cognitive Impairment|Inflammation|Interleukin-1beta|Lipopolysaccharides|Interleukin-6|Upregulation|*Macrophage Activation|Morris Water Maze Test 84 NPTX2 30902679 Neuroscience 2019 10.1016/j.neuroscience.2019.03.023 0 0 0 198 Animals|Mice|*DNA Methylation|*Pre-Conditioning, Ischemic|Middle Cerebral Artery Occlusion|Brain Ischemia|Stroke|Neuroprotective Effect|Neuroprotection|Disease Models, Animal|Signal Transduction|Glucose|*Gene Expression|Brain|Arid5a protein, mouse|DNA-Binding Proteins|Transcription Factors 84 NREP 31549395 J. Cell. Physiol. 2019 10.1002/jcp.29237 1 0 0 155 Animals|*Zebrafish|OLIG2 protein, human|*Oligodendrocyte Transcription Factor 2|*Motor Neuron|Zebrafish Proteins|*Neurogenesis|Embryo, Nonmammalian|Animals, Genetically Modified|Basic Helix-Loop-Helix Transcription Factors|Morpholinos|Cell Differentiation|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Messenger RNA|Embryo Development|Spinal Cord 46 NREP 30890858 Cancer Inform 2019 PMC6416685 10.1177/1176935119835522 3 0 0 155 Humans|Male|*Transcriptome|Canada|*Prostate Cancer|*Computational Biology|*Sequencing, Next-Generation|Gene Expression Profiling|Cancer Biomarkers|Prostate|Gene Expression Regulation, Neoplastic|Prognosis|Disease Progression|Machine Learning|FLVCR2 protein, human|Receptors, Virus|Membrane Transport Proteins|USP13 protein, human|Endopeptidases|GABPB1 protein, human 46 NUCKS1 31719764 Bioinformation 2019 PMC6822519 10.6026/97320630015548 0 0 0 269 Humans|Parkinson Disease 16|*Parkinson Disease|Genome-Wide Association Study|SNPs|Genetic Predisposition to Disease|Genotype-Phenotype Associations|Genotype|*Biomarkers|Case-Control Studies|Risk Factors 35 NUCKS1 31709175 Front Oncol 2019 PMC6823876 10.3389/fonc.2019.01063 0 0 0 269 35 NUCKS1 30847170 Mol Clin Oncol 2019 PMC6388501 10.3892/mco.2019.1795 3 4 0 269 Adult|Humans|Child|*Glioblastoma|*Up-Regulation|MIRN137 microRNA, human|MicroRNAs|*Transcriptional Activation|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Downregulation|Microarray Analysis|Gene Expression|MIRN490 microRNA, human|MIRN876 microRNA, human 35 NUCKS1 30710349 J. Cell. Physiol. 2019 10.1002/jcp.28240 1 6 0 269 Cattle|Female|Animals|Mice|Lactation|Sexual Maturation|*Milk|MTOR protein, human|TOR Serine-Threonine Kinases|*Cells, Epithelial|*Signal Transduction|Mammary Glands, Animal|Milk Protein|*Number, Cell|SREBP 1c|Casein|CCND1 protein, human|Cyclin D1|Phosphorylation|Cells, Cultured|Cell Proliferation|Amino Acids 35 NUPR1 31744261 Cells 2019 PMC6912534 10.3390/cells8111453 0 3 0 368 Pancreatic Carcinoma|*Pancreatic Neoplasms|*Adenocarcinoma|TP53INP1 protein, human|Neoplasm Proteins|*Heat-Shock Proteins|Basic Helix-Loop-Helix Transcription Factors|Cell Line, Tumor|Protein Binding 162 NUPR1 31667555 Cell. Mol. Life Sci. 2019 PMC7190594 10.1007/s00018-019-03347-3 1 0 0 368 *Intrinsically Disordered Proteins|*Malignancies|Drug Discovery 162 NUPR1 31654319 Mol. Neurobiol. 2019 10.1007/s12035-019-01809-0 1 2 0 368 Humans|Aged|*Alzheimer Disease|*Immunity, Humoral|Ubiquitin|Proteasome Endopeptidase Complex|Aging|Frameshift Mutation|Transcription, Genetic 162 NUPR1 31590125 Biomed. 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Rep. 2019 PMC6908941 10.3892/or.2019.7406 0 6 0 221 *Oxaliplatin|*Stomach Neoplasms|*Proteomics|Apoptosis|*Peptides|*Stomach|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Cell Survival|Downregulation 83 NUSAP1 31729978 J Ovarian Res 2019 PMC6857166 10.1186/s13048-019-0578-1 1 0 0 221 Humans|Female|*Computational Biology|*Prognosis|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Databases, Genetic|Transcriptome 83 OGFR 31835085 Int. 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Immunopharmacol. 2019 10.1016/j.intimp.2019.105723 0 5 0 69 Humans|Female|methionine-enkephalin receptor|*Prospective Studies|*Receptors, Opioid|Enkephalin, Methionine|Naltrexone|Narcotic Antagonists|*Cancer|Apoptosis|Cell Proliferation|RNA, Small Interfering|Viability, Cell|*Receptors, Growth Factor 102 OGFR 31404891 Int. Immunopharmacol. 2019 10.1016/j.intimp.2019.105785 0 3 0 69 *Narcotic Antagonists|Cancers|*Methionine Enkephalin|Naltrexone|methionine-enkephalin receptor|Receptors, Opioid|Naloxone|*Antineoplastic Agents|Cell Cycle|Opioid Peptides|Cell Proliferation 102 OGFR 30931654 Connect. 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J. 2019 PMC6759097 10.1097/CM9.0000000000000309 0 0 0 48 Humans|Pregnancy|Female|olfactomedin|Extracellular Matrix Proteins|Glycoproteins|*Tumorigenesis|*Cell Transformation, Neoplastic|*Embryonic Development|Amino Acid Sequence|Phylogeny 21 OLFML3 31141290 Vet Ophthalmol 2019 10.1111/vop.12680 0 0 0 48 Dogs|Animals|*Glaucoma, Angle-Closure|Polymorphism, Single Nucleotide|Glaucoma|Dog Diseases|United Kingdom|*Ligament 21 OLFML3 30696701 G3 (Bethesda) 2019 PMC6404605 10.1534/g3.118.200944 4 2 0 48 Dogs|Animals|olfactomedin|*Glutamine|*Arginine|*Glycoproteins|*Extracellular Matrix Proteins|Pedigree|Glaucoma|Anterior Chamber|Dog Diseases 21 ONECUT2 31882655 Sci Rep 2019 PMC6934839 10.1038/s41598-019-56277-2 1 0 0 153 *Genes, Homeobox|ONECUT2 protein, human|*Homeodomain Proteins|*Lung Adenocarcinoma|*Adenocarcinoma|Gene Expression Regulation, Neoplastic|Lung Cancer|*Disease Progression|A549 Cells|Polycomb Repressive Complex 2|MicroRNAs|Tumorigenesis|Cell Line, Tumor|Cell Proliferation|Cell Transformation, Neoplastic|Cell Differentiation|Bone Neoplasms 59 ONECUT2 31819483 Onco Targets Ther 2019 PMC6875498 10.2147/OTT.S227995 1 0 0 153 *Carcinoma, Non-Small-Cell Lung|*Lung Cancers|Neoplasm Recurrence, Local|Long Non-Coding RNA|ONECUT2 protein, human|*Homeodomain Proteins|*Transcription Factors|A549 Cells|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Up-Regulation|Cell Line, Tumor|Apoptosis 59 ONECUT2 31777606 J Cancer 2019 PMC6856882 10.7150/jca.28192 0 0 0 153 Humans|*Urinary Bladder Neoplasms|Hematuria|DNA Methylation|Biomarkers, Tumor|Receiver Operating Characteristic|Sensitivity and Specificity|Cohort Studies 59 ONECUT2 31623346 J Clin Med 2019 PMC6832722 10.3390/jcm8101603 0 2 0 153 *Epithelial-Mesenchymal Transition|*MicroRNAs|Gene Expression Regulation, Neoplastic|Colorectal Neoplasms|Cell Proliferation|Cell Line, Tumor|Cadherins 59 ONECUT2 31118200 Cancer Res. 2019 10.1158/0008-5472.CAN-18-4055 8 0 0 153 Humans|MIRN92 microRNA, human|*miRNAs|Cancer Stem Cell|*Extracellular Vesicle|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|MCF-7 Cells|Antineoplastic Agents|Doxorubicin|Cell Proliferation|Cell Line, Tumor|Xenograft Model Antitumor Assays|ONECUT2 protein, human|Homeodomain Proteins|Apoptosis|Transcription Factor 59 ONECUT2 31049588 Nucleic Acids Res. 2019 PMC6582315 10.1093/nar/gkz273 1 0 0 153 Humans|*Onecut Transcription Factors|*Chromatin|ONECUT2 protein, human|Homeodomain Proteins|Transcription Factors|Cellular Reprogramming|Induced Pluripotent Stem Cells|*Neurons|Fibroblasts|Genes, Homeobox|Cell Differentiation|Gene Expression Regulation, Developmental 59 ONECUT2 30934845 Int J Mol Sci 2019 PMC6480644 10.3390/ijms20071581 1 0 0 153 Mice|Animals|*Transcriptome|*Organoids|*Intestinal Mucosa|Colon|Germ-Free Life|Intestine, Small|cDNA Microarrays|Gene Expression Profiling|Microbiota 59 ONECUT2 30809552 Biomed Res Int 2019 PMC6369469 10.1155/2019/9642589 1 0 0 153 Mice|Animals|*RNA, Long Noncoding|*Alzheimer Disease|*Lipopolysaccharides|Neurodegenerative Diseases|mRNA|Hippocampus|Disease Models, Animal 59 ONECUT2 30655535 Nat Commun 2019 PMC6336817 10.1038/s41467-018-08133-6 14 1 0 153 Humans|Male|*Prostate|ONECUT2 protein, human|*Homeodomain Proteins|*Carcinoma, Neuroendocrine|*Transcription Factors|Receptors, Androgen|Neuroendocrine Tumors|Prostatic Neoplasms, Castration-Resistant|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|SOXB1 Transcription Factors|Signal Transduction|Cell Differentiation|Xenograft Model Antitumor Assays|Androgens 59 OSCP1 31095607 PLoS ONE 2019 PMC6522010 10.1371/journal.pone.0216705 4 0 0 406 Humans|Animals|Mice|Bayes Theorem|Proteomics|Cilium|Ciliopathies|Ciliary Motility Disorders|Genomics|Caenorhabditis elegans|Zebrafish|Exome|Base Sequence 62 OSCP1 30912283 Physiol Rep 2019 PMC6434071 10.14814/phy2.14042 1 6 0 406 Humans|*Insulin|*Diabetes Mellitus, Type 2|*Obesity|NR4A1 protein, human|*Nuclear Receptor Subfamily 4, Group A, Member 1|*Insulin, Regular, Human|*Muscle, Skeletal|*Exercise Training|Insulin Resistance|Euglycemic Clamps 62 OSR1 31811028 J. Neurosci. 2019 PMC6975285 10.1523/JNEUROSCI.0786-19.2019 0 4 0 215 Schizophrenia|DRD2 protein, human|Dopamine D2 Receptor|Genetic Predisposition to Disease|Prefrontal Cortex|Brain|Networks, Gene 326 OSR1 31792382 Nat. Cell Biol. 2019 PMC7140761 10.1038/s41556-019-0431-1 2 0 0 215 Phagocytes|*Chlorides|Phagocytosis|Signal Transduction|Sodium-Potassium-Chloride Symporters|Protein-Serine-Threonine Kinases|Phosphorylation|*Anti-Inflammatory Agents|Transcription Factors|Apoptosis|*Corpse 326 OSR1 31736353 Am. J. Physiol. Renal Physiol. 2019 PMC6985824 10.1152/ajprenal.00232.2019 1 2 0 215 *Hypokalemia|Solute Carrier Family 12, Member 3|WNK Lysine-Deficient Protein Kinase 1|Protein-Serine-Threonine Kinases|Kidney Tubules, Distal|Phosphorylation|Signal Transduction 326 OSR1 31729557 Pflugers Arch. 2019 PMC6892352 10.1007/s00424-019-02327-7 0 1 0 215 326 OSR1 31624705 Tissue Eng Regen Med 2019 PMC6778583 10.1007/s13770-019-00197-9 0 0 0 215 Humans|Animals|*Kidney|Regeneration|*Intermediate Mesoderm|Stem Cells|Tissue Scaffolds|Cell Differentiation|Tissue Engineering|Adipose Tissue|Cells, Cultured 326 OSR1 31614064 Chembiochem 2019 10.1002/cbic.201900454 0 6 0 215 *Phosphorylation|WNK Lysine-Deficient Protein Kinase 1|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|Sodium-Potassium-Chloride Symporters|Signal Transduction|Protein Kinases|Transcription Factors|Serine|Minor Histocompatibility Antigens|Amino Acid Sequence|Homeostasis|Threonine 326 OSR1 31561038 Cell Mol Gastroenterol Hepatol 2019 PMC6889609 10.1016/j.jcmgh.2019.09.003 0 4 0 215 *Bicarbonates|*Cystic Fibrosis Transmembrane Conductance Regulator|Cystic Fibrosis|*Pancreatitis|Chlorides|*Biological Transport|Hydrogen-Ion Concentration|Mutation 326 OSR2 31661087 Chem. Commun. (Camb.) 2019 10.1039/c9cc06589j 0 0 0 68 *Gold|*Aldehydes|Molecular Structure|carbene|Methane|Ligands|Crystallography, X-Ray|Stereoisomerism|Models, Molecular|Magnetic Resonance Spectroscopy 79 OSR2 31509714 J. Dent. Res. 2019 PMC6806131 10.1177/0022034519872478 1 0 0 68 Mice|Animals|*Hyaluronan Synthases|Palate|Cleft Palate|Neural Crest|Tongue|Gene Expression Regulation, Developmental|Transcription Factors|Mandible|Cell Proliferation 79 OSR2 31358051 Stem Cell Res Ther 2019 PMC6664599 10.1186/s13287-019-1340-8 0 0 0 68 Mice|Animals|*Proto-Oncogene Proteins c-akt|MTOR protein, human|*TOR Serine-Threonine Kinases|PTEN protein, human|*PTEN Phosphohydrolase|*Autophagy|Signal Transduction|*Palate|Cell Differentiation|Mesenchymal Stem Cells|MicroRNAs 79 OSR2 31340933 Development 2019 10.1242/dev.175042 1 2 0 68 Humans|*Genes, Homeobox|Homeodomain Proteins|Body Patterning|Facial Bones|Gene Expression Regulation, Developmental|Transcription Factors|Histone Acetyltransferases|Embryo, Mammalian|*Gene Expression|Mutation 79 OSR2 31240991 Organogenesis 2019 PMC6668654 10.1080/15476278.2019.1633871 0 3 0 68 Odontogenesis|*Signal Transduction|*Epithelium|MSX1 Transcription Factor|Mesoderm|Tooth|Transcription Factors|*Catenins|Bone Morphogenetic Protein 4|Gene Expression Regulation, Developmental 79 OTOF 31875531 Int. J. Pediatr. Otorhinolaryngol. 2019 10.1016/j.ijporl.2019.109831 0 0 0 118 *Hearing Loss|Deafness, Autosomal Recessive 9|Hearing Loss, Sensorineural|*Deafness|OTOF protein, human|Membrane Proteins|Auditory neuropathy|Hearing Loss, Central|Pedigree|Mutation 179 OTOF 31835641 Genes (Basel) 2019 PMC6947215 10.3390/genes10121031 0 0 0 118 Humans|Pakistan|*Homozygote|Deafness|Hearing Loss|Pedigree|Hearing Loss, Sensorineural|Genetic Testing|Serine Endopeptidases|Membrane Proteins|Mutation|High-Throughput Nucleotide Sequencing|Neoplasm Proteins|*Ethnic Groups 179 OTOF 31827501 Neural Plast. 2019 PMC6885821 10.1155/2019/9765276 1 0 0 118 Humans|Child|Infant|Auditory neuropathy|*Hearing Loss, Central|Mutation|Deafness|Membrane Proteins 179 OTOF 31782358 Comb. Chem. 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Genet. 2019 10.1111/cge.13638 2 0 0 118 Humans|*Whole Exome Sequencing|*Asian Continental Ancestry Group|Mutations|Deafness|Alleles|Connexins|Sequencing, Next-Generation|Pedigree|Frequencies, Allele|Genetic Variation|Genetic Testing|Hearing Loss|OTOF protein, human|Membrane Proteins 179 OTOF 31443490 Cells 2019 PMC6770723 10.3390/cells8090954 1 2 0 118 Animals|Humans|Endothelial Cells|OTOF protein, human|Membrane Proteins|Dysferlin|Muscle Proteins|Calcium-Binding Proteins|Cell Membrane|*Membrane|Cell Proliferation 179 OTOF 31325559 Toxicol. Appl. Pharmacol. 2019 10.1016/j.taap.2019.114686 1 3 0 118 *E3 Ligase|*Melatonin|Chromatography, Liquid|Tandem Mass Spectrometry|*Downregulation|Nedd4 Ubiquitin Protein Ligases|Endosomal Sorting Complexes Required for Transport|Upregulation|Ubiquitination|Ubiquitin|*Cell Survival|Protein Binding|Cells, Cultured|RNA, Small Interfering|Protein Transport|Cell Movement|Cycloheximide 179 OTOF 31250571 Mol Genet Genomic Med 2019 PMC6687625 10.1002/mgg3.808 2 0 0 118 Humans|cyclonite|*Hearing Loss|*Sequencing, Next-Generation|Nonsyndromic Deafness|Deafness|Hearing Loss, Sensorineural|Pedigree|Connexins|Heterozygote|Mutation|Myosins|OTOF protein, human|Membrane Proteins|MYO15A protein, human 179 OTOF 31095577 PLoS ONE 2019 PMC6522017 10.1371/journal.pone.0215932 4 0 0 118 Humans|Japan|Deafness, Autosomal Recessive 9|*Hearing Loss, Sensorineural|Auditory neuropathy|Hearing Loss, Central|*DNA Mutational Analysis|*Massively Parallel Sequencing|OTOF protein, human|Membrane Proteins|Mutations|*DNA|Implantation, Cochlear|Hearing Loss|Pedigree|Deafness|Homozygote|Phenotype 179 OTOG 31874721 Hear. Res. 2019 10.1016/j.heares.2019.107872 0 0 0 16 *Meniere Disease|Tinnitus|Ear, Inner|Hearing Loss, Sensorineural|Endolymph|Vertigo|Pedigree|Genetic Heterogeneity|Genes, Regulator|PRKCB protein, human|Protein Kinase C beta 35 OTOG 31776257 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6926040 10.1073/pnas.1902781116 2 0 0 16 Mice|Animals|*Tectorial Membrane|*Hair Cells, Auditory, Outer|*Stereocilia|Deafness, Autosomal Recessive 16|Hearing Loss, Sensorineural|Deafness|*Hair Cells, Vestibular|Sound|Proteins|Microscopy, Electron, Scanning 35 OTOG 31645975 Hum Genome Var 2019 PMC6804730 10.1038/s41439-019-0068-4 0 0 0 16 *Follow-Up Studies|*Hearing Loss|*Deafness|Hearing Loss, Sensorineural|Pedigree|Phenotype|Mutation|Membrane Glycoproteins 35 OTOG 31482700 Org. Lett. 2019 10.1021/acs.orglett.9b02771 0 0 0 16 *Olefins|*Ethers|carbene|*Catalysis|*Methane|Ruthenium|Molecular Structure|*Oximes|Stereoisomerism|Cyclopropanes 35 OTOG 30947719 Environ Health 2019 PMC6449917 10.1186/s12940-019-0471-9 1 0 0 16 Humans|*Hearing Loss, Noise-Induced|*Genetic Predisposition to Disease|*Polymorphism, Single Nucleotide|Noise, Occupational|Chinese|Genotype|Case-Control Studies|Occupational Exposure|Logistic Models 35 OTOG 30818062 Genomics 2019 10.1016/j.ygeno.2019.02.017 1 0 0 16 Humans|Animals|*Genome-Wide Association Study|*Ducks|Quantitative Trait Locus|SNPs|Genotype 35 OTOG 30800184 Beilstein J Org Chem 2019 PMC6369996 10.3762/bjoc.15.31 1 0 0 16 *Water|*Stereoisomerism|Catalysis|Ruthenium|Alkenes|Cyclopropanes 35 OTOP1 31543453 Curr. Biol. 2019 PMC7299528 10.1016/j.cub.2019.08.077 3 0 0 24 Animals|Mice|*Taste|*Protons|Taste Buds|Tongue|Acids|Action Potentials|Hydrogen-Ion Concentration|*B Cells 23 OTOP1 31543264 Cell 2019 10.1016/j.cell.2019.08.031 5 0 0 24 Animals|Mice|*Taste|Taste Buds|*Tongue|*Tongue Diseases|*Brain|Ganglia|Sensory Receptor Cells 23 OTOP1 31160780 Nat. Struct. Mol. Biol. 2019 PMC6564688 10.1038/s41594-019-0235-9 2 0 0 24 Animals|*Protons|Zebrafish|Zebrafish Proteins|Cryoelectron Microscopy|Evolution, Molecular|Models, Molecular|Membrane Proteins|Chicken|Mutagenesis|Taste Buds 23 OTOP1 30969887 J. Neurophysiol. 2019 10.1152/jn.00811.2018 2 0 0 24 Mice|Animals|*Reflex, Vestibulo-Ocular|*Otolithic Membrane|Semicircular Canals|Eye Movements|Rotation|*Adaptation, Physiological|Head|*Acclimatization|Ear|Macaca mulatta 23 OTOP1 30969882 J. Neurophysiol. 2019 10.1152/jn.00812.2018 2 0 0 24 Humans|Mice|Animals|*Reflex, Vestibulo-Ocular|*Otolithic Membrane|Semicircular Canals|Rotation|Vestibule, Labyrinth|Head Movements|Eye Movements|Ear|Adaptation, Physiological|*Otologic Surgical Procedures|Macaca mulatta 23 OTOP1 30686738 Curr. Biol. 2019 10.1016/j.cub.2018.12.007 8 0 0 24 Humans|Infant|Adult|Animals|Mice|*C57BL Mice|*Sleep|Wakefulness|Polysomnography|Electroencephalography|Sleep, Slow-Wave|*Stereotypic Movement Disorder|*Gray Matter|Vestibule, Labyrinth|Electromyography|Brain 23 Ovol1 31759386 Reprod. Biol. 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Neurosci. 2019 PMC6891064 10.1523/JNEUROSCI.0255-19.2019 3 0 0 174 Male|Rats|Animals|*Remifentanil|*Motivation|*Basal Forebrain|HCRT protein, human|*Orexins|1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea|Benzoxazoles|Orexin Receptors|Orexin Receptor Antagonists|*Analgesics, Opioid|Drug-Seeking Behavior|Naphthyridines|Conditioning, Operant|Reward|Extinction, Psychological|Rats, Sprague-Dawley|Self Administration|Behavioral Economics 123 oxr1 31332222 Sci Rep 2019 PMC6646313 10.1038/s41598-019-46843-z 1 2 0 174 Humans|calreticulin, human|*Calreticulin|*K562 Cells|JAK2 protein, human|Janus Kinase 2|Thrombocythemia, Essential|Myeloproliferative Disorders|Primary Myelofibrosis|Receptors, Thrombopoietin|*Mutations|Cell Transformation, Neoplastic|Frameshift Mutation|*Oxidative Stress 123 oxr1 31301273 Brain Res. 2019 10.1016/j.brainres.2019.146331 2 0 0 174 Mice|Animals|*Exosomes|*Parkinson Disease|*Oxidative Stress|Apoptosis|Downregulation|Dopaminergic Neurons|MicroRNAs|Up-Regulation|Disease Models, Animal|Cells, Cultured 123 oxr1 31112988 Neuropsychopharmacology 2019 PMC6785092 10.1038/s41386-019-0420-x 10 0 0 174 Rats|Animals|*Fentanyl|*Analgesics, Opioid|HCRT protein, human|*Orexins|Orexin Receptor Antagonists|Remifentanil|Orexin Receptors|Drug-Seeking Behavior|Conditioning, Operant|Benzoxazoles|Extinction, Psychological|Motivation|Reward|Rats, Sprague-Dawley|Self Administration|Behavioral Economics|Behavior, Animal|Cocaine 123 oxr1 31022673 Redox Biol 2019 PMC6479762 10.1016/j.redox.2019.101194 0 0 0 174 Mice|Animals|*Hyperoxia|*Homeostasis|*Aging|NFE2L2 protein, human|NF-E2-Related Factor 2|Oxidative Stress|Adaptation, Physiological|Signal Transduction Pathway|Proteasome Endopeptidase Complex 123 oxr1 31002819 Brain Res. 2019 PMC7083200 10.1016/j.brainres.2019.04.017 2 4 0 174 Rats|Animals|1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea|*Motivation|HCRT protein, human|*Orexins|*Benzoxazoles|*Naphthyridines|Drug-Seeking Behavior|*Urea|Reward|Orexin Receptors|Orexin Receptor Antagonists|Conditioning, Operant|Neuropeptide|Extinction, Psychological|Rats, Sprague-Dawley|Cues|Self Administration|Impulsivity 123 oxr1 30977043 Neurosci Bull 2019 PMC6754487 10.1007/s12264-019-00371-y 1 2 0 174 Animals|Rats|*Antioxidants|*RNA, Micro|Brain Ischemia|*Neurons|Neuroprotection|Middle Cerebral Artery Occlusion|Oxidative Stress|Stroke|Reperfusion Injury|Downregulation|Brain|Upregulation|Hydrogen Peroxide 123 oxsr1 31608673 Am. J. Physiol. Renal Physiol. 2019 PMC6960786 10.1152/ajprenal.00264.2019 1 4 0 594 Animals|Rats|*Rats, Sprague-Dawley|*Norepinephrine|*Sodium Chloride, Dietary|*Hypertension|Solute Carrier Family 12, Member 3|Blood Pressure|Kidney|Sodium Chloride Symporter Inhibitors|Sodium|*Sodium Chloride|Phosphorylation|Protein-Serine-Threonine Kinases 38 oxsr1 31362998 Biosci. Rep. 2019 PMC6692571 10.1042/BSR20190548 1 3 0 594 Rats|Animals|*Acute Kidney Injury|*Sepsis|CASP3 protein, human|Caspase 3|Apoptosis|Signal Transduction|Kidneys|MicroRNAs|Downregulation|Epithelial Cells|Inflammation|Up-Regulation|Cytokines|Oxidative Stress 38 P2RY8 31496804 Cancer Manag Res 2019 PMC6689548 10.2147/CMAR.S201177 3 0 0 46 *Squamous Cell Carcinoma of Head and Neck|*Gene Regulatory Networks|Head and Neck Neoplasms|Gene Expression Profiling|Transcriptome|Tumorigenesis 52 P2RY8 30977196 Immunol. Rev. 2019 PMC6464390 10.1111/imr.12743 3 0 0 46 *Immunity, Humoral|*Ligands|Germinal Center|Helper T-Cells|B Cells|*G-Protein-Coupled Receptors|Plasma Cells|Lymphocyte Activation|Antigen|Cell Differentiation 52 P2RY8 30859636 Genes Chromosomes Cancer 2019 10.1002/gcc.22748 0 1 0 46 Child|Humans|CRLF2 protein, human|*Receptors, Cytokine|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Prognosis|GATA3 protein, human|*GATA3 Transcription Factor|Receptors, Purinergic P2Y|Minimal Residual Disease|Risk Factors|*Germ Line|B-Lymphocytes|Berlin 52 P2RY8 30842656 Nature 2019 PMC6640153 10.1038/s41586-019-1003-z 7 1 0 46 Humans|*Glutathione|Germinal Center|*Receptors, Antigen, B-Cell|B-Lymphocytes|T-Lymphocytes, Helper-Inducer|*Receptors, G-Protein-Coupled|Lymphocyte Activation|*Ligands|Palatine Tonsil|Signal Transduction|P2RY8 protein, human|Receptors, Purinergic P2Y 52 PACRG 31735554 EBioMedicine 2019 PMC6921241 10.1016/j.ebiom.2019.10.061 0 0 0 62 *miRNA|*mRNA|*Hashimoto Disease|Genetic Predisposition to Disease|Gene Expression Profiling|Autoimmune Diseases|Case-Control Studies 68 PACRG 31333723 Front Genet 2019 PMC6624472 10.3389/fgene.2019.00646 4 0 0 62 Male|Cattle|Animals|*RNA, Long Noncoding|*mRNA|Sequencing, RNA|Gene Expression Profiling|Spermatogenesis 68 PACRG 31182890 Iran J Med Sci 2019 PMC6525733 1 1 0 62 Humans|Tuberculosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies 68 PACRG 31116684 Mol. Biol. Cell 2019 PMC6727744 10.1091/mbc.E19-01-0063 6 2 0 62 *Axonemes|Axonemal Dyneins|Cilia|Algal Proteins|Chlamydomonas reinhardtii|Flagella|Microtubules|Cell Movement 68 pacs2 31859489 Inorg Chem 2019 10.1021/acs.inorgchem.9b02545 0 0 0 228 Crystallography, X-Ray|Models, Molecular|*Electronic|*Heterocyclic Compounds 38 pacs2 31521637 Brain Res. 2019 10.1016/j.brainres.2019.146457 0 1 0 228 Humans|Infant, Newborn|*Epigenomics|*Autistic Disorder|Autism Spectrum Disorder|*Artificial Intelligence|DNA Methylation|CpG Islands|Epigenesis, Genetic|*Leukocytes|Case-Control Studies|Genes, Homeobox|*Biomarkers|Signal Transduction|Machine Learning|PACS2 protein, human|Vesicular Transport Proteins 38 pacs2 31460675 Ann. N. Y. Acad. Sci. 2019 10.1111/nyas.14212 0 0 0 228 *Endoplasmic Reticulum|*Mitochondria|Mitochondrial Membranes|Mitochondrial Dynamics|Calcium Signaling|Endoplasmic Reticulum Stress|Homeostasis|*Cell Physiological Phenomena|*Disorders, Neurological 38 pacs2 31432119 Mol Med Rep 2019 PMC6755151 10.3892/mmr.2019.10538 0 0 0 228 Rats|Animals|microtubule-associated protein 1B|Bayes Theorem|*Injury, Spinal Cord|Gene Regulatory Networks|*Microtubule-Associated Proteins|Gene Expression Profiling|Gene Expression Regulation|Protein Interaction Maps|Computational Biology|RNA, Micro|Cluster Analysis|Signal Transduction|Transcription Factor|*Neuroplasticity|Software 38 pacs2 31242668 Cells 2019 PMC6627983 10.3390/cells8060638 2 1 0 228 Humans|*Muscle, Smooth, Vascular|*Mitochondrial Membranes|*Mitochondria|Endoplasmic Reticulum|*Myocytes, Smooth Muscle|Mitophagy|*Protein Transport|Calcium Signaling|Apoptosis|HSD17B4 protein, human|*Peroxisomal Multifunctional Protein-2 38 pacs2 31210325 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201906_18079 0 2 0 228 *Myocytes, Cardiac|*Heart Failure|*Apoptosis|MicroRNAs 38 pacs2 30970236 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.04.002 4 10 0 228 oxidized low density lipoprotein|*Lipoproteins, LDL|*Mitochondria|*Apoptosis|*Endoplasmic Reticulum|Human Umbilical Vein Endothelial Cells|Endoplasmic Reticulum Stress|Reactive Oxygen Species|Oxidative Stress|Atherogenesis|Cell Survival 38 pacs2 30952494 Reprod. Biomed. Online 2019 10.1016/j.rbmo.2018.11.027 1 0 0 228 Male|Humans|Rats|Animals|*Streptozocin|*Testicular Diseases|*Nitrates|Testis|Spermatogenesis|*Nitrogen Oxides|Diabetes Mellitus, Experimental|Rats, Wistar|Spermatozoa|Oxidative Stress|Dietary Supplements 38 pacs2 30684285 Clin. Genet. 2019 10.1111/cge.13516 0 0 0 228 Child|Male|Humans|*Mutations|Phenotype|Sequencing, Whole Exome|Genetic Association Studies|Facies|Intellectual Disability|Mutation, Missense|Exome|Epilepsy, Generalized|Nervous System Malformations|Genetic Predisposition to Disease|Pedigree|Developmental Disabilities|Cerebellar Diseases|Alleles|PACS2 protein, human|Vesicular Transport Proteins 38 PAGE4 30813315 Biomolecules 2019 PMC6406393 10.3390/biom9020077 3 7 0 57 Humans|Male|*Prostate|Prostate Cancer|Androgen Antagonists|Intrinsically Disordered Proteins|Phosphorylation|Protein Conformation|Antigens, Neoplasm|Simulations, Molecular Dynamics|Protein Folding|Signal Transduction|Cell Line, Tumor|PAGE4 protein, human 31 PAGE4 30658679 J. Exp. Clin. Cancer Res. 2019 PMC6339303 10.1186/s13046-019-1032-3 0 7 0 57 Humans|Male|*MAP Kinase Signaling System|*Prostate|*Prostate Cancer|*Oxidative Stress|Cell Line, Tumor|Antigens, Neoplasm|Signal Transduction|Gene Expression Regulation, Neoplastic|Disease Progression|PAGE4 protein, human 31 PALMD 30905618 Cell Stem Cell 2019 10.1016/j.stem.2019.02.017 10 3 0 58 Humans|Mice|Animals|*Neocortex|Neurogenesis|Neural Stem Cells|Neurons|Gene Expression Regulation, Developmental|Ferret|Biological Evolution|Mammals|Cell Proliferation|Palmd protein, mouse|Membrane Proteins 20 PALMD 30694830 Curr Opin Endocrinol Diabetes Obes 2019 PMC6873465 10.1097/MED.0000000000000471 0 0 0 58 *Risk Factors|Aortic Valve, Calcification of|*Calcinosis|Aortic Valve Stenosis|Aortic Valve|Heart Valve Diseases|Mitral Valve|*Calcification, Physiologic|*Complement Factor B|3'-(1-butylphosphoryl)adenosine 20 PALMD 30608251 Curr. Opin. Cardiol. 2019 10.1097/HCO.0000000000000605 0 0 0 58 Aortic Valve, Calcification of|*Aortic Valve Stenosis|*Aortic Valve|*Calcinosis|*Genes, Regulator|Risk Factors 20 panx3 31822768 Sci Rep 2019 PMC6904572 10.1038/s41598-019-55371-9 0 2 0 117 Bone Formation|*Endoplasmic Reticulum|Gap Junctions|Osteoblasts|Cell Differentiation|Connexins|Chondrocytes|Cell Proliferation|Signal Transduction 67 panx3 31611621 Sci Rep 2019 PMC6791893 10.1038/s41598-019-51381-9 0 0 0 117 Humans|*Wnt Signaling Pathway|PIEZO1 protein, human|*Ion Channels|*Odontogenesis|Cell Differentiation|Cell Proliferation|Stem Cells|Cilia|*Biological Process 67 panx3 31202927 Bone 2019 10.1016/j.bone.2019.06.008 0 0 0 117 Mice|Animals|*Osteoblast|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Endochondral Ossification|Cell Differentiation|Connexins|*Bone Remodeling|Chondrocytes|Cell Proliferation|Bone|Panx1 protein, mouse|Nerve Tissue Proteins 67 panx3 30918989 J. Mol. Med. 2019 10.1007/s00109-019-01779-9 2 0 0 117 Mice|Animals|*Hearing|Connexins|Cochlea|Hearing Loss|*Skin|*Hearing Tests|Nerve Tissue Proteins|Knockout Mouse|Deafness|Epidermis|Glycoproteins|Panx1 protein, mouse 67 PARM1 31297877 J. Cell. Biochem. 2019 10.1002/jcb.29107 1 0 0 49 Male|*Prognosis|neurexophilin|*Prostate|Neoplasm Recurrence, Local|*Colorectal Cancer|*Glycoproteins|*Neuropeptides|*Colonic Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Protein Interaction Maps|Kaplan-Meier Analysis|Databases, Genetic|MUCL1 protein, human|*Mucins|Gene Regulatory Networks|Transcriptome 20 PARM1 31277570 BMC Dev. Biol. 2019 PMC6612098 10.1186/s12861-019-0195-7 1 4 0 49 Pregnancy|Male|Female|Cattle|Animals|*Prostate|*Blastocyst|Embryonic Development|Embryo Culture Techniques|Fertilization in Vitro|Gene Expression Regulation, Developmental|Endoplasmic Reticulum Stress|MUCL1 protein, human|*Mucins|Cell Differentiation|*Androgens|mRNA 20 PARM1 30678306 Biomolecules 2019 PMC6406848 10.3390/biom9020037 1 19 0 49 20 PARM1 30595163 J Sci Med Sport 2019 10.1016/j.jsams.2018.06.013 0 0 0 49 Humans|*Military Personnel|*Risk Factors|*Load-Bearing|*Overuse Injuries|Biomechanical Phenomena|Limb, Lower|Torso|Walking Speeds|Gait|Walking|Hip Joint|Knee Joint 20 PARP12 31798636 Front Genet 2019 PMC6863930 10.3389/fgene.2019.01142 0 0 0 93 20 PARP12 31103287 Fertil. Steril. 2019 10.1016/j.fertnstert.2019.03.020 1 2 0 93 Humans|Male|*DNA Methylation|*B-DNA|*Infertility, Male|CpG Islands|Oligospermia|Azoospermia|Spermatozoa|Spermatogenesis|Fertility|Case-Control Studies 20 PARP12 31095648 PLoS Pathog. 2019 PMC6521996 10.1371/journal.ppat.1007756 12 3 0 93 Humans|Mice|Animals|*Coronavirus|*Poly(ADP-ribose) Polymerase Inhibitors|*Coronavirus Infections|ADP Ribosylation|*Virus Replication|ADP-Ribose|Poly(ADP-ribose) Polymerases|ADP Ribosyltransferase|Viral Nonstructural Proteins|Immunity, Innate|Interferon|Togaviridae|RNA Viruses|Protein Processing, Post-Translational|Protein Domains|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Parp14 protein, mouse 20 PARP12 30742112 Nat. Genet. 2019 PMC6441365 10.1038/s41588-019-0351-9 18 0 0 93 Genome-Wide Association Study|*Transcriptome|*Quantitative Trait Loci|*Age Related Macular Degeneration|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|*Retina|Phenotype|Gene Expression Profiling 20 PARP12 30710058 Biochem. Soc. Trans. 2019 10.1042/BST20180416 5 0 0 93 *Poly(ADP-ribose) Polymerase Inhibitors|*ADP Ribosylation|Poly(ADP-ribose) Polymerases|Protein Processing, Post-Translational|Proteins|*Cytoplasm|ADP-Ribose 20 PARP3 31426748 BMC Plant Biol. 2019 PMC6701155 10.1186/s12870-019-1958-9 0 0 0 178 *Arabidopsis|*Poly(ADP-ribose) Polymerase Inhibitors|*Ribose|PARP3 protein, human|*Poly ADP Ribose Polymerase|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|*DNA Damage|Arabidopsis Proteins|Poly(ADP-Ribosyl)ation|DNA Repair|*Cell Cycle Proteins|ADP-Ribose|Posttranslational Modification|Mutation 80 PARP3 31095444 Cell Cycle 2019 PMC6592235 10.1080/15384101.2019.1617454 0 0 0 178 PARP3 protein, human|*Poly(ADP-ribose) Polymerases|*Cell Cycle Proteins|DNA Repair|Adenosine Diphosphate Ribose|DNA Damage|Protein Processing, Post-Translational|Neoplasms 80 PARP3 31085801 Aging (Albany NY) 2019 PMC6535076 10.18632/aging.101959 0 0 0 178 Humans|Mice|Animals|*Poly ADP Ribosylation|PARP2 protein, human|Poly(ADP-ribose) Polymerases|*Base Excision Repair|PARP3 protein, human|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Poly Adenosine Diphosphate Ribose|ADP-Ribose|MARylation|DNA Damage|*DNA Replication|DNA|*Mole Rats|Cell Cycle Proteins|Plant Extracts 80 PARP3 30910692 Biochem. Pharmacol. 2019 PMC7056360 10.1016/j.bcp.2019.03.028 0 1 0 178 PARP2 protein, human|*Poly(ADP-ribose) Polymerases|PARP3 protein, human|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|DNA Breaks, Double-Stranded|Poly(ADP-ribose) Polymerase Inhibitors|DNA Repair|Cell Cycle Proteins|DNA Damage|Mitosis|DNA|Cell Cycle|Cell Cycle Checkpoint 80 PARP3 30664952 J Proteomics 2019 10.1016/j.jprot.2019.01.012 0 1 0 178 Animals|*Chickens|*Proteomics|*Spleen|*Stress, Heat|*Heat Stress Disorders|Avian Proteins|*Immunity, Innate|*Cell Death|Hot Temperature|Stress, Physiological|Signal Transduction 80 PARP3 30635165 EBioMedicine 2019 PMC6412162 10.1016/j.ebiom.2018.12.060 4 7 0 178 Humans|*Poly(ADP-ribose) Polymerase Inhibitors|gemcitabine|veliparib|*Deoxycytidine|*Benzimidazoles|*Antineoplastic Agents|Antineoplastic Combined Chemotherapy Protocols|Capecitabine|Pancreatic Neoplasms|Maximum Tolerated Dose|Poly (ADP-Ribose) Polymerase-1|Prognosis 80 parpbp 31770211 Medicine (Baltimore) 2019 PMC6890310 10.1097/MD.0000000000017997 1 0 0 100 *Nasopharyngeal Carcinoma|*Computational Biology|Neoplasm Recurrence, Local|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Software|Gene Expression Regulation, Neoplastic|Protein Interaction Mapping|Nasopharyngeal Neoplasms|Biomarkers, Tumor|Epistasis, Genetic 25 parpbp 31612171 Nanoscale 2019 PMC6964798 10.1039/c9nr07104k 0 0 0 100 *Microscopy, Atomic Force|DNA|Streptavidin|Adsorption|Protein Binding|Aluminum Silicates|DNA-Binding Proteins|*Biophysical Phenomena|*Biochemical Phenomena|Polyethylene Glycols 25 parpbp 31611199 Ann. Clin. Lab. Sci. 2019 0 0 0 100 PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|*Lung Adenocarcinoma|*Cell Proliferation|A549 Cells|Cell Movement|Gene Expression Regulation, Neoplastic|Up-Regulation|Lung Neoplasms|TYRP1 protein, human|*Membrane Glycoproteins|Proto-Oncogene Proteins c-akt|Prognosis|Cell Line, Tumor|Disease Progression 25 parpbp 30967629 Oncogene 2019 10.1038/s41388-019-0810-x 0 5 0 100 Humans|Mice|Animals|Leukemia, Myeloid|HL-60 Cells|*Hematopoiesis|Cell Differentiation|DNA Damage|U937 Cells|Cell Proliferation|DNA Repair|Cell Line, Tumor|DNA-Binding Proteins|NF-kappa B 25 parpbp 30949905 Dig. Dis. Sci. 2019 10.1007/s10620-019-05608-4 2 0 0 100 *Carcinoma, Hepatocellular|*Liver Neoplasms|Gene Expression Regulation, Neoplastic|MicroRNAs|Biomarkers, Tumor|Prognosis|Kaplan-Meier Estimate|Up-Regulation|Disease-Free Survival|*Neoplastic Processes|Proportional Hazards Models|Real-Time Polymerase Chain Reaction 25 parpbp 30811978 Cell Rep 2019 10.1016/j.celrep.2019.01.109 1 1 0 100 Animals|Mice|*Glioblastoma|*Down-Regulation|*Drug Resistance, Neoplasm|Temozolomide|Dacarbazine|Brain Neoplasms|Antineoplastic Agents, Alkylating|*Transcription Factors|Cell Line, Tumor|Apoptosis|Cell Proliferation|HDAC1 protein, human|Histone Deacetylase 1|Gene Knockdown Techniques|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|RNA, Small Interfering 25 PART1 31698132 J Pain 2019 10.1016/j.jpain.2019.10.009 0 0 0 0 *Ownership|*Hot Temperature|Illusions|Touch Perception|*Pain Perception|Hand|Visual Perception|Proprioception|Body Image|Pain|Artificial Limbs 48 PART1 31669140 Int. J. 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Cell Biol. 2019 10.1016/j.biocel.2019.105637 0 2 0 0 *RNA, Long Noncoding|*Wnt Pathway|CTNNB1 protein, human|*beta Catenin|*Colorectal Cancer|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|*Catenins|Up-Regulation|Cell Line, Tumor|Carcinogenesis|Cell Movement|Apoptosis|*Colonic Neoplasms 48 PART1 31646607 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201910_19124 1 2 0 0 *RNA, Long Noncoding|*Chondrocytes|*Osteoarthritis|*Apoptosis|MicroRNAs|Cell Proliferation|Cartilages, Articular|Cells, Cultured|Extracellular Matrix 48 PART1 31607839 Front Neurosci 2019 PMC6771308 10.3389/fnins.2019.00937 0 0 0 0 *Computational Biology|Neuroendocrine Tumors|X-linked Nuclear Protein|Pancreatic Neoplasms|Adaptor Proteins, Signal Transducing|Nuclear Proteins|*Disease Progression|Biomarkers, Tumor 48 PART1 31436388 Cancer Med 2019 PMC6792487 10.1002/cam4.2494 5 4 0 0 Male|Animals|*Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Cancer|*Prostate|*Janus Kinases|*Signal Transduction|MicroRNAs|Cell Proliferation|JAK1 protein, human|Janus Kinase 1|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|*Disease Progression|*Androgens 48 PART1 31367490 PeerJ 2019 PMC6657684 10.7717/peerj.7380 2 0 0 0 lncRNA|*Laryngeal Neoplasms|miRNAs|Gene Regulatory Networks|RNA, Messenger|Prognosis|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Transcriptome|Biomarkers, Tumor|Kaplan-Meier Estimate|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms 48 PART1 31349831 BMC Oral Health 2019 PMC6660658 10.1186/s12903-019-0834-1 0 1 0 0 Tooth Abrasion|Tooth Erosion|Tooth Attrition|Toothbrushing|Toothpastes|Saliva, Artificial|Hardness|Citric Acid|Hydrogen-Ion Concentration 48 PART1 31323300 J Ethnopharmacol 2019 10.1016/j.jep.2019.112096 0 1 0 0 Mice|Animals|*Bleomycin|*Epithelial-Mesenchymal Transition|*NF kB|*Phosphorylation|*Pulmonary Fibrosis|Smad3 Protein|Transforming Growth Factor beta1|Lung|Transforming Growth Factor beta|*Carbolines|*Alkaloids 48 pax6a 30671985 J Appl Toxicol 2019 10.1002/jat.3770 1 0 0 0 United States|Humans|Animals|Child|*Zebrafish|*Arsenic|Water Pollutants, Chemical|Gene Expression|Neurogenesis 32 pax6a 30648819 Birth Defects Res 2019 10.1002/bdr2.1458 2 1 0 0 Animals|Female|Humans|Pregnancy|*Zebrafish|*Fetal Alcohol Spectrum Disorders|*Ethanol|*Cannabinoids|Hedgehog Proteins|Embryo, Nonmammalian|Embryogenesis 32 PCAT1 31694571 BMC Cancer 2019 PMC6836529 10.1186/s12885-019-6180-5 3 0 0 0 *RNA, Long Noncoding|*Colorectal Cancer|*Adenoma|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Biomarkers, Tumor|Gene Regulatory Networks|*Carcinoma, Transitional Cell|RNA, Messenger|*Colonic Neoplasms 57 PCAT1 31646554 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201910_19133 2 0 0 0 Humans|Female|*RNA, Long Noncoding|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|Up-Regulation|Gene Knockdown Techniques|NEK2 protein, human|NIMA-Related Kinases 57 PCAT1 31595574 J. Cell. Biochem. 2019 10.1002/jcb.29406 0 7 0 0 Humans|Male|Female|*RNA, Long Noncoding|*Endometriosis|Infertility, Female|*Signal Transduction|*Single Nucleotide Polymorphism|MicroRNAs|*Genes, Neoplasm|Cell Proliferation|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|F11R protein, human|Cell Adhesion Molecules|SERPINE1 protein, human|Plasminogen Activator Inhibitor 1|Cell Line, Tumor|Receptors, Cell Surface|MSI2 protein, human|RNA-Binding Proteins 57 PCAT1 31464517 DNA Cell Biol. 2019 PMC6822575 10.1089/dna.2019.4834 0 0 0 0 Male|Humans|*RNA, Long Noncoding|*Lung Neoplasms|*Chinese|Single Nucleotide Polymorphisms|Carcinoma, Non-Small-Cell Lung|Genetic Predisposition to Disease|Genetic Association Studies|Carcinoma, Squamous Cell|Case-Control Studies|Risk Factors|Smoking|Prostatic Neoplasms 57 PCAT1 31352238 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109255 2 0 0 0 Humans|Male|*Cisplatin|*RNA, Long Noncoding|*Stomach Neoplasms|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|MicroRNAs|Cell Line, Tumor|Cell Proliferation|Cell Movement|Up-Regulation|ZEB1 protein, human|Zinc Finger E-box-Binding Homeobox 1|MIRN128 microRNA, human 57 PCAT1 31351391 J Psychiatr Res 2019 10.1016/j.jpsychires.2019.07.004 1 0 0 0 Humans|Animals|Mice|*Depressive Disorder, Major|*RNA, Long Noncoding|Case-Control Studies|Biomarkers|Leukocytes|Real-Time Polymerase Chain Reaction 57 PCAT1 31308362 Nat Commun 2019 PMC6629701 10.1038/s41467-019-10808-7 3 2 0 0 Humans|Male|*Transcriptome|*Prostate Cancer|Transcriptional Regulator ERG|Prostate|TMPRSS2 protein, human|Serine Endopeptidases|AR protein, human|Androgen Receptor|Oncogene Proteins, Fusion|Oncogene Fusion|Trans-Activators|Gene Expression Regulation, Neoplastic|Cohort Studies|HOXA4 protein, human|Homeodomain Proteins 57 PCAT1 31273188 Cell Death Dis 2019 PMC6609620 10.1038/s41419-019-1745-4 4 0 0 0 Humans|Male|*Esophageal Squamous Cell Carcinoma|*RNA, Long Noncoding|*Cell Proliferation|Gene Expression Regulation, Neoplastic|*Cell Cycle|MicroRNAs|Esophageal Neoplasms|Cell Line, Tumor|Cell Movement|Up-Regulation|Disease Progression|*Biomarkers|Apoptosis|MIRN326 microRNA, human 57 PCAT1 31253700 Biosci. Rep. 2019 PMC6629943 10.1042/BSR20190708 2 0 0 0 57 PCAT6 31676070 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.10.136 2 5 0 0 Humans|*RNA, Long Noncoding|*Osteosarcoma|TGFBR1 protein, human|TGFBR1|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor|Upregulation|Apoptosis|Disease Progression|Signal Transduction|*Neoplastic Processes|MIRN185 microRNA, human 23 PCAT6 31646553 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201910_19132 2 1 0 0 Humans|Female|*RNA, Long Noncoding|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|PTEN protein, human|*PTEN Phosphohydrolase|RNA Interference|RNA, Small Interfering|Cell Proliferation|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic 23 PCAT6 31632586 Am J Transl Res 2019 PMC6789233 1 2 0 0 *RNA, Long Noncoding|*Cholangiocarcinoma|*Cell Proliferation|MicroRNAs|Liver Neoplasms|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Bile Ducts, Intrahepatic|Downregulation|Cell Line, Tumor|Oncogenes|Apoptosis|*Neoplastic Processes|Bile Duct Neoplasms 23 PCAT6 31571902 Onco Targets Ther 2019 PMC6750713 10.2147/OTT.S214336 2 1 0 0 Humans|*Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|*Cell Proliferation|*Up-Regulation|*Cell Cycle|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Tumorigenesis|Cell Line, Tumor|Kruppel-Like Transcription Factors|Apoptosis|Cell Transformation, Neoplastic 23 PCAT6 31336224 Biosens Bioelectron 2019 10.1016/j.bios.2019.111523 2 0 0 0 Humans|*RNA, Long Noncoding|*Fluorescence|*Color|*Lung Cancer|*Oligonucleotide Array Sequence Analysis|Biomarkers, Tumor|*Extracellular Vesicle|Gene Expression Regulation, Neoplastic|Receiver Operating Characteristic|Gene Expression Profiling|Area Under Curve|Quantitative Real Time Polymerase Chain Reaction 23 PCAT6 31328973 Genet Test Mol Biomarkers 2019 10.1089/gtmb.2018.0308 1 0 0 0 23 PCAT6 30968586 Cancer Med 2019 PMC6558594 10.1002/cam4.2141 3 1 0 0 Male|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*Gene Amplification|*Testis|*Liver Neoplasms|*Cell Proliferation|Gene Expression Regulation, Neoplastic|Prognosis|MicroRNAs|Oncogenes|Cell Line, Tumor|Liver 23 PCAT6 30938104 Cancer Med 2019 PMC6536993 10.1002/cam4.1809 5 8 0 0 Humans|Male|*RNA, Long Noncoding|*5 Fluorouracil|*Drug Resistance, Neoplasm|Phosphatidylinositol 3-Kinases|*HMGA2 Protein|*Colorectal Cancer|*Signal Transduction|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Upregulation|Downregulation|Cell Line, Tumor|Prognosis|Apoptosis|*Colonic Neoplasms|MIRN204 microRNA, human 23 PCAT6 30915737 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201903_17233 2 5 0 0 Male|Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Wnt Pathway|*Cell Proliferation|Cell Movement|*Catenins|beta Catenin|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Line, Tumor|Oncogene|*Cell Cycle|Disease Progression|Prognosis 23 PCDH19 31747920 Mol Brain 2019 PMC6864969 10.1186/s13041-019-0519-3 0 0 0 74 Humans|Male|Female|Mice|Animals|*Autistic Disorder|Epilepsy|Mental Retardation|Heterozygote|Mutations|Cadherins|Phenotypes|Mice, Knockout|PCDH19 protein, human 151 PCDH19 31714027 Brain Behav 2019 PMC6908879 10.1002/brb3.1455 2 0 0 74 Humans|Female|*Epilepsy|Seizures|*Clustering|Electroencephalography|Pedigree|Cadherins|Genetic Predisposition to Disease|Mutation|PCDH19 protein, human 151 PCDH19 31678000 Epilepsy Behav 2019 10.1016/j.yebeh.2019.106539 2 0 0 74 Humans|Female|Child|*Status Epilepticus|Seizures|Epilepsy|Drugs, Antiepileptic|Epileptic Syndrome|Electroencephalography|Intellectual Disability|Cadherins|Autism|Mutation|Clustering|London|PCDH19 protein, human 151 PCDH19 31665840 Zhonghua Er Ke Za Zhi 2019 10.3760/cma.j.issn.0578-1310.2019.11.008 0 0 0 74 151 PCDH19 31497230 Am J Transl Res 2019 PMC6731421 0 0 0 74 TGFB1 protein, human|*Transforming Growth Factor beta1|*Cell Differentiation|*Smooth Muscle Cells|*Muscle Development|Transforming Growth Factor beta|Mesenchymal Stem Cells|Cells, Cultured|Stem Cell|Actins 151 PCDH19 31477701 Nat Commun 2019 PMC6718393 10.1038/s41467-019-11854-x 1 1 0 74 Animals|Mice|*Neurogenesis|*Cerebral Cortex|Brachyury protein|T-Box Domain Proteins|Neurons|Neural Stem Cells|Gene Expression Regulation, Developmental|Neuroglia|Cell Differentiation|Nerve Tissue Proteins|Mice, Transgenic|Embryo, Mammalian|*Mammals|Mice, Inbred C57BL|Fetal Proteins 151 PCDH19 31471553 J. Hum. Genet. 2019 10.1038/s10038-019-0661-x 2 0 0 74 Child|Humans|*DNA Copy Number Variations|Spasms, Infantile|Epileptic Seizures|Methyl-CpG-Binding Protein 2|Cohort Studies|PCDH19 protein, human|Cadherins 151 PCDH8 30779884 Reprod. Fertil. Dev. 2019 10.1071/RD18314 1 1 0 136 Pregnancy|Male|Female|Mice|Animals|*Epithelial-Mesenchymal Transition|*ICR Mice|TWIST2 protein, human|*Twist-Related Protein 1|*Implantation, Embryo|*Repressor Proteins|CDH1 protein, human|N-Cadherin|Endometrium|Vimentin|Antigens, CD|Downregulation|Transcription Factors|Upregulation|Epithelium|Immunohistochemistry 88 Pcdh9 31632082 Onco Targets Ther 2019 PMC6790212 10.2147/OTT.S220339 2 1 0 84 63 Pcdh9 31191202 Mol Syndromol 2019 PMC6528091 10.1159/000497402 1 0 0 84 63 Pcdh9 31154861 Int J Food Sci Nutr 2019 10.1080/09637486.2019.1614541 0 2 0 84 63 Pcdh9 31059116 Ginekol. Pol. 2019 10.5603/GP.2019.0040 2 0 0 84 Humans|Female|*Semaphorin-3A|*Drug Resistance, Neoplasm|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Carcinogenesis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Antineoplastic Agents|Apoptosis|Calcium-Binding Proteins|S100A3 protein, human|S100 Proteins|PCDH9 protein, human|Cadherins|SEMA3A protein, human 63 PCLO 31885998 Case Rep Pediatr 2019 PMC6925823 10.1155/2019/7048537 0 0 0 129 Pontocerebellar Hypoplasia|*Autopsy|*Cerebellar Diseases|Pontocerebellar Hypoplasia Type 3|Olivopontocerebellar Atrophies|Cerebellum|Homozygote|Mutation|*Chromosome Structures|Seizures 132 PCLO 31767149 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.11.092 0 0 0 129 Humans|*Proteomics|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|*Hematopoietic Stem Cells|Neoplastic Stem Cells|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Antineoplastic Agents|DPP4 protein, human|Dipeptidyl Peptidase 4 132 PCLO 31753095 Zhongguo Dang Dai Er Ke Za Zhi 2019 0 0 0 129 Female|Pregnancy|Animals|Rats|*White Matter|Rats, Sprague-Dawley|Animals, Newborn|Hypoxia-Ischemia, Brain|Myelin Basic Protein|Brain|*Brain Injuries|Disease Models, Animal|*Premature Birth|*Hippocampus 132 PCLO 31745835 Mol. Neurobiol. 2019 10.1007/s12035-019-01785-5 2 3 0 129 Rats|Animals|*Wnt Signaling Pathway|Synapses|Hippocampus|Neurons|Synaptic Plasticity|Wnt Proteins|Neurogenesis|Presynaptic Terminals|Postsynaptic Density Protein 95|Ctbp1 protein, rat|Carrier Proteins|Transcription Factors|Shank1 protein, rat|Nerve Tissue Proteins 132 PCLO 31580838 Neuropharmacology 2019 10.1016/j.neuropharm.2019.107803 0 0 0 129 Humans|Infant|Animals|Rats|Infant, Newborn|*Neuroprotective Agents|*Leptin|Preterm Infants|*Ischemia-Hypoxia, Brain|*Hippocampus|Chromatography, Liquid|Tandem Mass Spectrometry|Animals, Newborn|Brain Injuries|Brain|Peptides|Disease Models, Animal|Hypoxia 132 PCLO 31417239 Drug Des Devel Ther 2019 PMC6594009 10.2147/DDDT.S205633 1 0 0 129 Humans|*Etoposide|*Small Cell Lung Carcinoma|PE regimen|Cisplatin|Lung Neoplasms|Antineoplastic Combined Chemotherapy Protocols|Cell Line, Tumor|Apoptosis|Epirubicin|Mutation 132 PCLO 31164688 Sci Rep 2019 PMC6547758 10.1038/s41598-019-44143-0 0 0 0 129 Mice|Animals|*Tobacco, Smokeless|*Oncogenes|PIK3CA protein, human|*Class I Phosphatidylinositol 3-Kinases|*Mutation|Tongue Neoplasms|Oral Cancer|*Genomics|Squamous Cell Carcinoma|High-Throughput Nucleotide Sequencing|Squamous Cell Carcinoma of Head and Neck|Sequencing, Whole Exome|*Oncogenesis|Phosphatidylinositol 3-Kinases|Cell Line, Tumor|Tumor Suppressor Protein p53|Head and Neck Neoplasms 132 PCLO 31074746 Elife 2019 PMC6541439 10.7554/eLife.46629 2 2 0 129 Rats|Animals|*Synaptic Vesicles|PCLO protein, human|Cytoskeletal Proteins|Neuropeptides|Synapses|Presynaptic Terminals|Nerve Tissue Proteins|Neurons|Endosomes|Endocytosis|Hippocampus 132 PCLO 30855010 Arch. Esp. Urol. 2019 0 0 0 129 Humans|Male|United States|Middle Aged|Aged|*Prostate-Specific Antigen|Early Detection of Cancer|Prostate Cancer|*Screening|Overdiagnosis|Task Force|African Americans|Incidence|*Biomarkers 132 PCLO 30696732 J. Neurosci. 2019 PMC6445989 10.1523/JNEUROSCI.2038-18.2019 4 0 0 129 Male|Female|Rats|Animals|*Synapses|*Retinal Neurons|Synaptic Transmission|Retina|Nerve Tissue Proteins|Protein Isoforms|DNA-Binding Proteins|Phosphoproteins|*Transcription Factors|Alcohol Oxidoreductases|*Cytoskeleton|Neurotransmitters 132 PCNP 31592414 Adv Sci (Weinh) 2019 PMC6774057 10.1002/advs.201900809 0 0 0 156 Humans|Rats|Animals|*Peritoneal Diseases|Tissue Adhesions|Peritoneum|Postoperative Complications 59 PCNP 31521522 Pain Manag Nurs 2019 10.1016/j.pmn.2019.06.016 1 0 0 156 Humans|Adult|*Pain|Analgesics, Opioid|Opioid-Related Disorders 59 PCNP 31487123 Cancer Med 2019 PMC6797571 10.1002/cam4.2465 1 0 0 156 *Nuclear Protein|Phosphatidylinositol 3-Kinases|MTOR protein, human|TOR Serine-Threonine Kinases|Signal Transduction|E3 Ligase|Ubiquitin|Adaptor Proteins, Signal Transducing|RBX1 protein, human|Carrier Proteins|Ubiquitination|Cell Cycle|Cell Proliferation|Apoptosis|Post-Translational Modifications|Neuroblastoma|Threonine|Serine 59 PCNP 31013196 Int J Palliat Nurs 2019 10.12968/ijpn.2019.25.4.186 0 0 0 156 Humans|*Palliative Care|Israel|Nurse Practitioner|Nurse's Role|Practice Patterns, Nurses'|*Nurse Clinicians|Surveys and Questionnaires 59 PCNP 30872582 Oncogenesis 2019 PMC6418141 10.1038/s41389-019-0132-4 2 23 0 156 Humans|*Nuclear Protein|Phosphatidylinositol 3-Kinases|*Lung Adenocarcinoma|*Cell Proliferation|MTOR protein, human|Mammalian Target of Rapamycin|Phosphatidylinositol 3-Kinase|Proto-Oncogene Proteins c-akt|Signal Transduction|Lung Cancer|Apoptosis|Adenocarcinoma|Up-Regulation|Cell Line, Tumor|Autophagy|Downregulation|Gene Expression Regulation, Neoplastic|Neovascularization, Pathologic 59 PCP4 31112769 Microb. Pathog. 2019 10.1016/j.micpath.2019.103546 2 0 0 105 Humans|*Streptococcus mutans|*Anti-Infective Agents|*Antibiotics|Biofilm|Microbial Sensitivity Tests|Pep19-2.5 peptide|*Peptides|Penicillin|Microscopy, Electron, Scanning|*Biological Phenomena 109 PCP4 31098764 Brain Struct Funct 2019 10.1007/s00429-019-01883-z 6 0 0 105 Mice|Animals|*GABAergic Neurons|*Vasoactive Intestinal Peptide|*Transcriptome|Interneurons|*Subiculum|Cells, Pyramidal|Dendrites|Presynaptic Terminals|preproenkephalin|Enkephalins|gamma-Aminobutyric Acid|Muscarinic Receptor|Acetylcholine|proenkephalin|Protein Precursors|Pcp4 protein, mouse|Nerve Tissue Proteins 109 PCP4 30919954 J. Comp. Neurol. 2019 PMC6879308 10.1002/cne.24688 1 0 0 105 Animals|Finches|Amygdala|Vocalization, Animal|Neural Pathways|Prosencephalon 109 PCP4 30768950 Neurosci. Res. 2019 10.1016/j.neures.2019.02.001 0 0 0 105 Rats|Mice|Animals|*Subiculum|Pyramidal Neurons|Dendrites|Calbindin|Presynaptic Terminals|Immunohistochemistry|Pcp4 protein, mouse|Nerve Tissue Proteins 109 PCP4 30759386 Cell Rep 2019 PMC6389459 10.1016/j.celrep.2019.01.060 1 3 0 105 Rats|Animals|*Hippocampus|Theta Rhythm|Memory|Pyramidal Cells|Action Potentials|Neurons|Membrane Potentials 109 PCP4 30744532 Reprod Sci 2019 10.1177/1933719119828072 0 2 0 105 Pregnancy|Female|Humans|*Myometrium|*Calmodulin|Labor, Obstetric|Obstetric Labor, Premature 109 PDE3B signalling 31519735 Biochem. J. 2019 PMC6792037 10.1042/BCJ20190594 5 2 0 0 Female|Humans|*Lipolysis|*Diabetes Mellitus, Type 2|*Adipocytes|B-insulin|*Insulin|*Receptors, Adrenergic|Adipose Tissue|*Signal Transduction|Receptors, Adrenergic, beta|Insulin Resistance|Obesity|Acids, Fatty|Epinephrine|*Biotin|Insulin, Regular, Human|Phosphorylation 21 pdia2 31706267 Mol. Med. 2019 PMC6842480 10.1186/s10020-019-0113-2 2 0 0 61 *Transcriptome|*Prognosis|*Transcriptome Analysis|*Pancreatic Cancer|Tumor Markers|Gene Regulatory Networks|Protein Interaction Maps|Gene Ontology|Computational Biology|Gene Expression Regulation, Neoplastic 23 pdia2 31223040 Hemoglobin 2019 10.1080/03630269.2019.1625786 1 0 0 61 Pregnancy|Female|Humans|Belgium|alpha-Thalassemia|alpha-Globins|Hemoglobins, Abnormal|Hydrops Fetalis|Hemoglobinopathy|Sequence Deletion|Prenatal Diagnosis|Phenotype 23 PDLIM1 31509262 Hepatology 2019 10.1002/hep.30930 2 2 0 164 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Neoplasm Recurrence, Local|*Signal Transduction|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|PDLIM4 protein, human|LIM Domain Proteins|Prognosis|Gene Expression Regulation, Neoplastic|DNA-Binding Proteins|Cell Line, Tumor|Cell Movement|Hep G2 Cells|Cadherins|Up-Regulation|Transcription Factors|Cell Proliferation 43 PDLIM1 31014114 Syst Biol Reprod Med 2019 10.1080/19396368.2019.1606361 3 1 0 164 Male|*Autophagy|Apoptosis|*Male Reproductive System 43 PDZD2 31594751 EBioMedicine 2019 PMC6838402 10.1016/j.ebiom.2019.09.019 1 8 0 125 *Proto-Oncogene Proteins c-akt|*Myocardial Reperfusion Injury|*Myocardial Ischemia|*Myocardial Reperfusion|*Coronary Artery Disease|Phosphatidylinositol 3-Kinases|Myocardial Infarction|Signal Transduction|G-Protein-Coupled Receptor Kinase 2|*Ischemia|Apoptosis|Heart Failure 57 PDZD2 31570735 Sci Rep 2019 PMC6769015 10.1038/s41598-019-50171-7 3 1 0 125 Humans|*Stomach Neoplasms|Exome|Paraffin Embedding|*Neoplastic Processes|Mutation|High-Throughput Nucleotide Sequencing|Sequencing, Whole Exome|Formaldehyde|*Biomarkers 57 PDZD2 30896877 Oncol. Rep. 2019 PMC6448123 10.3892/or.2019.7078 2 8 0 125 Male|*Osteosarcoma|MicroRNAs|Bone Neoplasms|Epithelial-Mesenchymal Transition|*Genes, Tumor Suppressor|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Cell Proliferation|Downregulation|Apoptosis|Cell Line, Tumor|Cell Movement|Upregulation|Genes, cdc 57 PDZD2 30644608 Mol. Carcinog. 2019 10.1002/mc.22975 0 0 0 125 Humans|Male|*Prostatic Neoplasms, Castration-Resistant|Neoplasm Recurrence, Local|Prostate cancer, familial|PTEN protein, human|PTEN Phosphohydrolase|*Genomics|3' UTR|Genes, BRCA2|BRCA2 protein, human|BRCA2 Protein|BRCA1 protein, human|BRCA1 Protein|5' UTR|HOXB13 protein, human|Homeodomain Proteins|Introns 57 PDZD7 31454969 Int J Mol Sci 2019 PMC6747409 10.3390/ijms20174174 0 0 0 36 *Founder Effect|Pedigree|Heterozygote|Hearing Loss, Sensorineural|Haplotypes|Deafness|Alleles|Mutation|Carrier Proteins 30 PDZD7 31231422 Front Genet 2019 PMC6558366 10.3389/fgene.2019.00501 1 0 0 36 *Usher Syndromes|Cuba|*Genetic Screening|Pedigree|Mutation|High-Throughput Nucleotide Sequencing|Adaptor Proteins, Signal Transducing|Europe|Africa|South America 30 PDZD7 31129248 Gene 2019 10.1016/j.gene.2019.05.045 0 0 0 36 Humans|*Pedigree|*Deafness|*Hearing Loss, Sensorineural|*Chinese|Genes, Recessive|Hearing Loss|Exome|DNA Mutational Analysis|Heterozygote|Genetic Predisposition to Disease|Mutation|Amino Acid Sequence|Carrier Proteins|PDZD7 protein, human 30 PDZD7 30786928 J. 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Cancer Res. 2019 PMC6381703 10.1186/s13046-019-1106-2 0 34 0 36 Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Enhancer of Zeste Homolog 2 Protein|MicroRNAs|Gene Expression Regulation, Neoplastic|Long Non-Coding RNA|Hep G2 Cells|Polycomb Repressive Complex 2|Cell Line, Tumor|Cell Proliferation|*Gene Expression|Epigenesis, Genetic|Mice, Nude|Tumorigenesis|Signal Transduction|Disease Progression|PDZD7 protein, mouse|Carrier Proteins 30 PDZRN3 31098988 J Physiol Sci 2019 10.1007/s12576-019-00681-w 0 8 0 80 *PDZ Domains|*Carrier Proteins|*RING Finger Domains|Biological Transport|Monocarboxylic Acid Transporters|Kidney Tubules, Proximal|Ion Transport|Yeast Two-Hybrid Assay|Membrane Proteins|Cell Line|*Transcription Factors|Sodium|Co-Immunoprecipitation|RNA, Messenger 26 PEG3 31850059 Front Genet 2019 PMC6902642 10.3389/fgene.2019.01180 1 0 0 229 Humans|Gene Regulatory Networks|*Signal Transduction|Transcription Factors|Gene Expression Regulation, Neoplastic|Computational Biology|Genes, Homeobox|Tumors|Algorithm 460 PEG3 31828718 Mol Imaging Biol 2019 10.1007/s11307-019-01460-0 0 2 0 229 Fluorine-18|phosphatidylethanolamine|*Phosphatidylethanolamines|Tomography, X-Ray Computed|*Fluorine Radioisotopes|Positron Emission Tomography|Radiopharmaceuticals|*Apoptosis|Cell Line, Tumor|Amino Acid Sequence|Tissue Distribution 460 PEG3 31683583 Int J Mol Sci 2019 PMC6862121 10.3390/ijms20215428 0 0 0 229 Mice|Animals|*Epiblast|*Parthenogenesis|Embryonic Stem Cells|Pluripotent Stem Cells|Genomic Imprinting|Induced Pluripotent Stem Cells|DNA Methylation|Cell Differentiation|Cell Line|Gene Expression Regulation, Developmental|Gene Expression Profiling|Cells, Cultured|Gene Expression 460 PEG3 31639176 PLoS ONE 2019 PMC6804975 10.1371/journal.pone.0224287 0 0 0 229 Animals|Mice|*Alleles|Genomic Imprinting|*Regulatory Sequences, Nucleic Acid|Kruppel-Like Transcription Factors|DNA Methylation|Nerve Tissue Proteins|Zinc Fingers|Carrier Proteins|Gene Expression Regulation, Developmental|Promoter Regions, Genetic|Ubiquitin-Specific Proteases|Mutation|Peg3 protein, mouse|Zim1 protein, mouse 460 PEG3 31571274 Anim. Genet. 2019 10.1111/age.12861 0 0 0 229 Pregnancy|Humans|Infant, Newborn|Animals|Female|Cattle|Mice|Sheep|Swine|*Intrauterine Growth Restriction|Epigenesis, Genetic|IGF2 protein, human|IGF-2|DNA Methylation|Genomic Imprinting|Placenta|Promoter Regions, Genetic|Gene Expression Regulation, Developmental|*Infant, Small for Gestational Age|*DNA 460 PGAP3 31805394 Eur J Med Genet 2019 10.1016/j.ejmg.2019.103822 0 0 0 17 Humans|Cricetinae|Animals|*Glycosylphosphatidylinositols|Cricetulus|Hyperphosphatasia with Mental Retardation|Phosphorus Metabolism Disorders|Intellectual Disability|Abnormalities, Multiple|FRAG1 protein, human|*Nuclear Proteins|Phenotype|Mutations|Pedigree|Amino Acid Sequence|Homozygote|Mutation, Missense|Syndrome|CHO Cells|Golgi Apparatus|Diabetes Mellitus, Type 2 39 PGAP3 31684969 Diagn Pathol 2019 PMC6829978 10.1186/s13000-019-0902-5 0 0 0 17 Hyperphosphatasia with Mental Retardation|*Mental Retardation|Phosphorus Metabolism Disorders|Abnormalities, Multiple|Pedigree|Phenotype|Genetic Predisposition to Disease|Glycosylphosphatidylinositol|Syndrome|Mutation 39 PGAP3 30813920 BMC Pediatr 2019 PMC6394075 10.1186/s12887-019-1440-8 1 5 0 17 Male|Humans|*Intellectual Disability|Phosphorus Metabolism Disorders|*Mutations|*Syndrome|Abnormalities, Multiple|Phenotype|Pedigree|PGAP3 protein, human|Receptors, Cell Surface|Epilepsy|FRAG1 protein, human|Nuclear Proteins|Amino Acid Sequence|PIGO protein, human|Membrane Proteins|PIGL protein, human|N-Acetylglucosaminyltransferases 39 PGAP3 30728244 J. 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Chem. 2019 PMC6442038 10.1074/jbc.RA119.007472 6 1 0 17 Animals|Mice|*Glycosylphosphatidylinositols|*Cell Membrane|Endoplasmic Reticulum|Cell Surface Proteins|Mannose|*Mammals|Cell Line 39 PGAP3 30710169 Virchows Arch. 2019 10.1007/s00428-018-02516-2 2 0 0 17 Humans|Female|*Endometrial Carcinoma|Carcinoma, Endometrioid|Cystadenocarcinoma, Serous|Adenocarcinoma, Clear Cell|SMARCA4 protein, human|Nuclear Proteins|Transcription Factors|Mutation|PTEN protein, human|PTEN Phosphohydrolase|DNA Mutational Analysis|Genes, Regulator|ARID1A protein, human|Immunohistochemistry|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Microsatellite Instability|Oncogenes 39 PGDF 31360011 Asian J Transfus Sci 2019 PMC6580828 10.4103/ajts.AJTS_25_17 0 4 0 0 *Wound Healing|Platelet Rich Plasma|Platelets|Proto-Oncogene Proteins c-sis|Becaplermin|Platelet Count|Transforming Growth Factor beta1|Growth Factors 49 PGDF 31226756 Mar Drugs 2019 PMC6627327 10.3390/md17060365 0 0 0 0 Mice|Animals|*Hydrogels|*Chitosan|BMP2 protein, human|Bone Morphogenetic Protein 2|Alginate|Platelet-Derived Growth Factor BB|Osteogenesis|Microspheres|Proto-Oncogene Proteins c-sis|Tissue Scaffolds|Cell Differentiation|Mice, Inbred BALB C 49 PGDF 31053727 Sci Rep 2019 PMC6499837 10.1038/s41598-019-42601-3 7 6 0 0 Humans|*Chondrocytes|Tifab protein, human|*TNF Receptor-Associated Factor 6|*RNA, Micro|*Signal Transduction|MMP13 protein, human|Matrix Metalloproteinase 13|3' Untranslated Region|Up-Regulation|Downregulation|Osteoarthritis|Interleukin-1beta|NF-kappa B|MAPK, p38|mRNA|Bioinformatics 49 pgm5 31858536 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201912_19767 1 0 0 35 Humans|*Carcinoma, Renal Cell|*RNA, Long Noncoding|*Down-Regulation|Kidney Neoplasms|Gene Expression Regulation, Neoplastic|Prognosis|Cell Proliferation|Tumorigenesis|Biomarkers, Tumor|Cell Line, Tumor|Cell Movement|Apoptosis|Kaplan-Meier Estimate|*Neoplastic Processes 38 pgm5 31781598 Biomed Res Int 2019 PMC6874998 10.1155/2019/2183510 1 0 0 35 Humans|Aged|*Stomach Neoplasms|*Genomics|*Databases, Genetic|Immunotherapy|Antigens, Neoplasm|Exome|Mutations|*Survey|Immunologic Factors 38 pgm5 31619123 Cancer Biol. Ther. 2019 PMC7012094 10.1080/15384047.2019.1673098 3 4 0 35 Animals|*RNA, Long Noncoding|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|Downregulation|Cell Proliferation|Sequencing, RNA|Apoptosis|Cell Movement|Cell Line, Tumor|RNA, Messenger|Genes, Tumor Suppressor|*Colonic Neoplasms|Gene Ontology 38 pgm5 31608179 PeerJ 2019 PMC6786248 10.7717/peerj.7821 1 0 0 35 *RNA, Long Noncoding|*Transcriptome|Gene Regulatory Networks|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|MicroRNAs|Gene Expression Profiling|RNA, Messenger|Gene Ontology|Kaplan-Meier Estimate|Data Mining 38 pgm5 31582909 Cancer Cell Int. 2019 PMC6771116 10.1186/s12935-019-0967-y 2 2 0 35 Humans|*Prognosis|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|Cell Movement|Biomarkers, Tumor|Cell Proliferation|Kaplan-Meier Estimate|Cell Line, Tumor|*Colonic Neoplasms|Lymphatic Metastasis|Apoptosis 38 pgm5 31345222 BMC Med Genomics 2019 PMC6657027 10.1186/s12920-019-0543-2 0 0 0 35 Humans|*Posttranslational Modification|Databases, Protein|*Mutations|Phosphorylation|Cancer 38 pgm5 31218127 PeerJ 2019 PMC6568247 10.7717/peerj.7070 16 0 0 35 *Prognosis|*Liver Cancer|Carcinoma, Hepatocellular|Biomarkers, Tumor|Area Under Curve|ROC Curve|Kaplan-Meier Estimate 38 pgm5 31185143 IUBMB Life 2019 10.1002/iub.2069 4 5 0 35 Humans|*Esophageal Squamous Cell Carcinoma|*RNA, Long Noncoding|*Tumor Suppressor Protein p53|*Esophageal Neoplasms|PTEN protein, human|*PTEN Phosphohydrolase|*Disease Progression|Gene Expression Regulation, Neoplastic|MicroRNAs|Neoplasm Invasiveness|Cell Proliferation|Downregulation|Cell Movement|Genes, Tumor Suppressor|Cell Line, Tumor|Lymphatic Metastasis|Biomarkers, Tumor|Apoptosis 38 PHACTR1 31838046 J. 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Cardiol. 2019 10.1016/j.jacc.2018.09.085 6 0 0 73 Middle Aged|Humans|Female|*Endothelin-1|*Coronary Vessels|Coronary Artery Dissection, Spontaneous|*Coronary Vessel Anomalies|*Vascular Diseases|Dysplasia, Fibromuscular|*Locus, Genetic|Coronary Angiography|Syndromes, Acute Coronary|Risk Factors|Prevalence|Coronary Artery Disease 75 PHACTR1 30610379 J Neural Transm (Vienna) 2019 10.1007/s00702-018-01966-x 2 0 0 73 Humans|*Selective Serotonin Reuptake Inhibitors|*Depressive Disorder, Major|*Coronary Artery Disease|*Obesity|Antidepressants|Multifactorial Inheritance|Genetic Predisposition to Disease 75 PHF6 31831722 J Assoc Genet Technol 2019 0 1 0 176 Adult|Child|Male|Humans|Young Adult|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|FBXW7 protein, human|F-Box-WD Repeat-Containing Protein 7|*Mutations|F-Box Proteins|*Leukemia, T-Cell|Receptor, Notch1|Prognosis|Cell Cycle Proteins|Ubiquitin-Protein Ligases|Lymphoblastic Leukemia|Phenotype|Mutations, Missense 171 PHF6 31782600 EMBO Rep. 2019 PMC6944915 10.15252/embr.201948460 0 0 0 176 *DNA End-Joining Repair|*G2 Phase Cell Cycle Checkpoints|Mental Retardation, X-Linked|Carrier Proteins|Chromatin|*Transcription Factors|DNA Repair|DNA|Chromatin Assembly and Disassembly|DNA Damage 171 PHF6 31746849 Chem. Commun. (Camb.) 2019 10.1039/c9cc06868f 0 0 0 176 *Tryptophan|*Glucosamine|tau Proteins|Amyloid|Peptide Fragments|Amino Acid Sequence|Peptides|In Silico|Microscopy, Electron, Transmission 171 PHF6 31694105 Zhonghua Yi Xue Za Zhi 2019 10.3760/cma.j.issn.0376-2491.2019.40.005 0 0 0 176 171 PHF6 31661961 ACS Chem Neurosci 2019 10.1021/acschemneuro.9b00488 1 0 0 176 *tau Proteins|*Molecular Dynamics Simulation|Neurofibrillary Tangles|Alzheimer Disease|Tauopathies 171 PHF6 31572674 Front Oncol 2019 PMC6753626 10.3389/fonc.2019.00871 0 0 0 176 Humans|*DNA Copy Number Variations|*Multiplex Polymerase Chain Reaction|Retrospective Studies|*Leukemia, Biphenotypic, Acute|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Gene Dosage|Ikaros Transcription Factor|Acute Lymphoblastic Leukemia|Minimal Residual Disease|Gene Deletion|Mutation 171 PHF6 31565104 Dis. 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Med. 2019 10.1080/14767058.2019.1702952 0 0 0 478 89 phlda2 31491693 Placenta 2019 10.1016/j.placenta.2019.08.087 0 1 0 478 Animals|Mice|Pregnancy|Humans|Female|*Glucose Transporter|*Assisted Reproductive Technology|Placentas|Genomic Imprinting|Insulin-Like Growth Factor II|DNA Methylation|RNA, Long Noncoding|*Signal Transduction|Glucose|TOR Serine-Threonine Kinases|MTOR protein, human 89 phlda2 31469872 PLoS ONE 2019 PMC6716778 10.1371/journal.pone.0221972 0 4 0 478 Infant, Newborn|Humans|Female|Pregnancy|*DNA Methylation|*Gestational Age|*B-DNA|*Placenta|Fetal Growth Restriction|CpG Islands|Promoter Regions, Genetic|Infant, Small for Gestational Age|Ultrasonography, Doppler|Leptin|Fetus|VEGFA protein, human|Vascular Endothelial Growth Factor A 89 phlda2 31242935 Clin Epigenetics 2019 PMC6595585 10.1186/s13148-019-0692-3 1 0 0 478 Animals|Humans|Female|Pregnancy|Genomic Imprinting|*Alleles|Placenta|Epigenesis, Genetic|DNA Methylation|Fetal Growth Retardation|Insulin-Like Growth Factor II|Pre-Eclampsia|Fetal Growth|Transcriptome|Gestational Diabetes 89 phlda2 31194812 PLoS ONE 2019 PMC6564030 10.1371/journal.pone.0218278 1 0 0 478 Infant|Child|Humans|Infant, Newborn|Female|Pregnancy|IGF2 protein, human|*Insulin-Like Growth Factor II|*Gestational Age|*Infant, Small for Gestational Age|*Infant, Low Birth Weight|CDKN1C protein, human|Cyclin-Dependent Kinase Inhibitor p57|Birth Weight|*Placenta|*Parturition|Child Development|Proteins 89 phlda2 31105744 Front Genet 2019 PMC6499025 10.3389/fgene.2019.00373 4 0 0 478 Humans|Female|*Prognosis|*Endometrial Cancer|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Computational Biology|Kaplan-Meier Estimate 89 phlda2 31067459 Cell Rep 2019 PMC6555151 10.1016/j.celrep.2019.04.056 5 1 0 478 *Single-Cell Analysis|Cellular Reprogramming|Induced Pluripotent Stem Cells|SOX2 protein, human|SOXB1 Transcription Factors|Nanog Homeobox Protein|Cell Differentiation|Fibroblasts|Transcription Factors|Gene Expression Regulation, Developmental|Cells, Cultured|Signal Transduction|Gene Activation|EPCAM protein, human|EpCAM 89 phlda2 31058093 Front Oncol 2019 PMC6482205 10.3389/fonc.2019.00298 1 4 0 478 Humans|Mice|Animals|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Up-Regulation|*Osteosarcoma|*Signal Transduction|Bone Neoplasms|miRNAs|*Pleckstrin Homology Domain|PTEN Phosphohydrolase|Gene Expression Regulation, Neoplastic|3' Untranslated Region|Phosphatidylinositol 3-Kinase|Downregulation|Cell Proliferation|Cell Line, Tumor|Apoptosis|*Transcriptional Activation|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 89 phlda2 30771304 Dev. Biol. 2019 PMC6451886 10.1016/j.ydbio.2019.01.019 0 0 0 478 Humans|Animals|Mice|Female|Pregnancy|*Trophoblasts|*DNA Methylation|*Glycogen|*Placenta|Placental Development|Intrauterine Growth Restriction|Genomic Imprinting|Gene Expression Regulation, Developmental|Embryo, Mammalian|Transcriptome Profile|Cell Proliferation|MicroRNAs|MIRN126 microRNA, human 89 phlda2 32270973 Pediatr Endocrinol Diabetes Metab 2019 10.5114/pedm.2019.91547 0 0 0 478 Humans|Child|Female|Pregnancy|Epigenesis, Genetic|Sexual Maturation|IGF2 protein, human|IGF-2|Fetal Growth Retardation|Placenta|Genomic Imprinting|Fetal Growth|Fetus|Gene Expression Regulation, Developmental|Mutation 89 PHLDB1 31842352 Cancers (Basel) 2019 PMC6966482 10.3390/cancers11122001 0 0 0 51 Genome-Wide Association Study|Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Mutation|*Risk Factors|Biomarkers, Tumor|Genetic Loci|Case-Control Studies 41 PHLDB1 31721021 Mol. Biol. 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Neurobiol. 2019 10.1007/s10571-019-00712-5 0 0 0 23 Humans|*Alzheimer Disease|*Herpesvirus 1, Human|Neurodegenerative Diseases|Cognitive Impairment, Mild|*Antibodies, Viral|Herpes Simplex|Receptors, Immunologic|IgG1|Atrophy|PILRA protein, human|Membrane Glycoproteins 38 PIM2 31827987 Cureus 2019 PMC6890153 10.7759/cureus.6052 0 0 0 477 Child|Humans|*Intensive Care Units, Pediatric|Hospital Mortality|Length of Stay|Heart Defects, Congenital 333 PIM2 31784324 An Pediatr (Barc) 2019 10.1016/j.anpedi.2019.05.018 0 0 0 477 Child|Humans|*Organ Dysfunction Scores|Systemic Inflammatory Response Syndrome|Sepsis|*Pediatric Intensive Care Units|Hospital Mortality|Retrospective Studies|ROC Curve|Prognosis|Consensus 333 PIM2 31745166 Sci Rep 2019 PMC6864106 10.1038/s41598-019-53669-2 0 0 0 477 *TNF Receptor-Associated Factor 3|PIM2 protein, human|*Proto-Oncogene Proteins|*Protein-Serine-Threonine Kinases|*B Cells 333 PIM2 31730483 Cell Commun. 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Clin. Lab. Sci. 2019 0 0 0 271 *A549 Cells|*Down-Regulation|*Lung Adenocarcinoma|*Apoptosis|Cell Proliferation|Protein-Serine-Threonine Kinases|Cell Cycle|Cell Line, Tumor|siRNA|STAT3 Transcription Factor|Signal Transduction|Phosphorylation|Gene Expression Regulation, Neoplastic|Lung Neoplasms 172 PIM3 31748181 Aust Crit Care 2019 10.1016/j.aucc.2019.08.002 0 0 0 271 Child|Humans|*Suction|Intubation, Intratracheal|Intensive Care Units, Pediatric|*Trachea|Australia 172 PIM3 31730483 Cell Commun. Signal 2019 PMC6858710 10.1186/s12964-019-0463-y 1 11 0 271 Humans|Male|*Phosphorylation|proto-oncogene proteins pim|Proto-Oncogene Proteins c-pim-1|*Cell Migration|*Prostate Cancer|Prostate|Cell Line, Tumor|Cell Proliferation|Post-Translational Modifications|*Neoplastic Processes|Signal Transduction|Transcription Factor, NFATC1|PIM1 protein, human|NFATC1 protein, human 172 PIM3 31397090 Physiol Rep 2019 PMC6687858 10.14814/phy2.14177 0 0 0 271 *Aldosterone|*Serine Threonine Kinase|*Nephron|Immediate-Early Proteins|*Transcription Factors|Epithelial Sodium Channels|Sodium|Nuclear Proteins|Kidney 172 PIM3 31319208 Fish Shellfish Immunol. 2019 10.1016/j.fsi.2019.07.036 0 1 0 271 Animals|*Palaemonidae|*Hepatopancreas|*Ammonia|*Transcriptome Analysis|Arthropod Proteins|Transcriptome|High-Throughput Nucleotide Sequencing|Stress, Physiological|Signal Transduction 172 PIM3 31310053 EMBO Mol Med 2019 PMC6685085 10.15252/emmm.201810058 3 4 0 271 Humans|Child|*Phosphatidylinositol 3-Kinases|*Protein Kinase Inhibitors|*Neuroblastoma|MTOR protein, human|TOR Serine-Threonine Kinases|Phosphoinositide-3 Kinase Inhibitors|N-Myc Proto-Oncogene Protein|Proto-Oncogene Proteins c-akt|Apoptosis|Phosphatidylinositol 3-Kinase|Xenograft Model Antitumor Assays|Signal Transduction|Cell Line, Tumor|Pyrimidines|Cell Proliferation|Pyridines|Doxorubicin|Antineoplastic Combined Chemotherapy Protocols 172 PIM3 31260686 Life Sci. 2019 10.1016/j.lfs.2019.116615 2 0 0 271 *Stomach Neoplasms|bufothionine|*Indole Alkaloids|huachansu|Amphibian Venoms|*Quinolinium Compounds|cinobufagin|Bufanolides|Cell Proliferation|Cell Line, Tumor|Apoptosis|Signal Transduction 172 PIM3 31201037 Aust Crit Care 2019 10.1016/j.aucc.2019.05.003 0 0 0 271 Child|Humans|*Catheters, Indwelling|*Peripheral Arterial Catheterizations|Central Venous Catheters|Catheter-Related Infections|Critical Care|*Cannula|Phlebotomy|*Clinical Audit 172 PIM3 31073371 Oncotarget 2019 PMC6497463 10.18632/oncotarget.26876 3 7 0 271 Humans|Mice|Animals|proto-oncogene proteins pim|AZD1208|*Leukemia, Lymphocytic, Chronic, B-Cell|Proto-Oncogene Proteins c-pim-1|*Thiazolidines|*Biphenyl Compounds|*Protein Kinase Inhibitors|*Autophagy|Apoptosis|Serine Threonine Kinases|Phosphorylation|Cell Proliferation|Cell Line, Tumor|Leukemia, Myeloid, Acute|Cell Survival|Cell Death 172 PIM3 31015445 Nat Commun 2019 PMC6479052 10.1038/s41467-019-09867-7 2 9 0 271 *SAM Domain and HD Domain-Containing Protein 1|proto-oncogene proteins pim|*Phosphorylation|HIV-2|*Proto-Oncogene Proteins c-pim-1|Viral Regulatory and Accessory Proteins|HIV-1|Virus Replication|Monomeric GTP-Binding Proteins|HIV Infections|Host-Pathogen Interactions|Proteolysis|Lentiviruses|Serine Threonine Protein Kinases 172 PIM3 30898394 J. Pediatr. Surg. 2019 PMC6545248 10.1016/j.jpedsurg.2019.02.029 2 0 0 271 Humans|Mice|Animals|Child|*Hepatoblastoma|*Cell Transformation, Neoplastic|*Tumorigenesis|Liver Neoplasms|Proto-Oncogene Proteins|Protein-Serine-Threonine Kinases|Gene Expression Regulation, Neoplastic|*Tumor Initiating Cell|Cell Line, Tumor|Cell Proliferation|*Phenotype|PIM3 protein, human 172 PIM3 30827510 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.02.123 2 8 0 271 *Cell Proliferation|*Colorectal Cancer|*Apoptosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|*Colonic Neoplasms|*Cholesterol 172 PIM3 30654529 Int J Mol Sci 2019 PMC6359068 10.3390/ijms20020363 1 15 0 271 Humans|proto-oncogene proteins pim|AZD1208|*Phosphorylation|*AMP-Activated Protein Kinases|Proto-Oncogene Proteins c-pim-1|*Thiazolidines|MTOR protein, human|*Mammalian Target of Rapamycin|*Biphenyl Compounds|*Protein Kinase Inhibitors|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|Cell Proliferation|Cell Survival|Apoptosis|*Liposarcoma|Cell Line, Tumor|Antineoplastic Agents 172 PIN4 31817249 Int J Mol Sci 2019 PMC6941128 10.3390/ijms20246120 0 1 0 144 Auxin|Arabidopsis Proteins|Arabidopsis|AKT1 protein, human|*Protein Kinase B|gibberellic acid|Gibberellins|Gene Expression Regulation, Plant|Biological Transport|Plant Roots|Signal Transduction|Membrane Transport Proteins|Phosphorylation|Plants, Genetically Modified|*Embryogenesis|CRK5 protein, Arabidopsis|Receptors, Cell Surface|Protein-Serine-Threonine Kinases 96 PIN4 31779904 Plant Sci. 2019 10.1016/j.plantsci.2019.110294 0 5 0 144 *Arabidopsis|*Seedlings|*Etiolations|Auxins|Hypocotyls|Arabidopsis Proteins|Plant Roots|Gene Expression Regulation, Plant|*Biological Transport|Membrane Transport Proteins|F-Box Proteins|*Floods|LAX2 protein, Arabidopsis 96 PIN4 31472226 Food Chem. Toxicol. 2019 10.1016/j.fct.2019.110796 0 7 0 144 Mice|Animals|*Rubus|*Hyperlipidemias|*Diet, High-Fat|Triglycerides|HMGCR protein, human|Hydroxymethylglutaryl CoA Reductases|Cholesterol|Lipogenesis|Liver|CYP7A1 protein, human|Cholesterol 7-alpha-Hydroxylase|Lipid Metabolism|PPAR alpha|Plant Extracts|*Signal Transduction|Mice, Inbred C57BL 96 PIN4 31299202 Cell 2019 10.1016/j.cell.2019.06.021 2 0 0 144 *Arabidopsis|Auxin|Arabidopsis Proteins|*Biological Transport|Plant Growth Regulators|Gene Expression Regulation, Plant|Plant Roots|Seedlings|Membrane Transport Proteins|Plants, Genetically Modified 96 PIN4 31010613 Plant Physiol. Biochem. 2019 10.1016/j.plaphy.2019.04.020 0 0 0 144 *Arabidopsis|weisiensin B|Auxin|Arabidopsis Proteins|*Diterpenes|*Biological Transport|Meristems|Plant Roots|Seedlings|*Organogenesis, Plant|Gene Expression Regulation, Plant|Signal Transduction|Green Fluorescent Proteins 96 PIN4 30865619 PLoS Genet. 2019 PMC6433298 10.1371/journal.pgen.1008023 2 0 0 144 *Transcription Factor|Auxin|Arabidopsis|Arabidopsis Proteins|Meristem|Plant Shoots|*Biological Transport|Plant Growth Regulators|Gene Expression Regulation, Plant|Cytokinins|Membrane Transport Proteins|Plant Leaves|Phenotype|Mutation|Signal Transduction|Lactones|BRC1 protein, Arabidopsis|ABCB19 protein, Arabidopsis 96 PIWIL3 31358756 Nat Commun 2019 PMC6662892 10.1038/s41467-019-11312-8 1 0 0 21 Male|Humans|Mice|Animals|*Piwi-Interacting RNA|*Oocytes|Argonaute Proteins|Transposable Elements|Testis|Sequencing, RNA|RNA, Messenger|Transcriptome|Base Sequence 24 pkd1l1 31642198 Mol Genet Genomic Med 2019 PMC6900395 10.1002/mgg3.1015 1 0 0 17 *Thyroid Cancer, Papillary|Thyroid Cancers|Carcinoma, Papillary|*Mutations|*Neoplastic Syndromes, Hereditary|Carcinoma|Germ-Line Mutation|Genetic Predisposition to Disease 20 pkd1l1 31026592 Eur J Med Genet 2019 10.1016/j.ejmg.2019.04.014 0 0 0 17 Animals|*Heterotaxy Syndrome|Situs Inversus|*Fetuses|Lateral Plate Mesoderm|Membrane Proteins|PKD1L1 protein, human 20 pkd1l1 30664273 Hepatology 2019 PMC6642859 10.1002/hep.30515 2 0 0 17 Infant|Humans|Child|Mice|Animals|*Biliary Atresia|*Splenic Diseases|*Spleen|*Abnormalities, Multiple|Potter Type III Polycystic Kidney Disease|*Polycystic Kidney Diseases|Liver|Liver Transplantation|PKD1L1 protein, human|Membrane Proteins 20 Pl15 31624143 J. Biol. Chem. 2019 PMC6885643 10.1074/jbc.RA119.010716 0 0 0 0 poly(beta-D-mannuronate) lyase|*Polysaccharide-Lyases|Protein Conformation|Substrate Specificity|Crystallography, X-Ray|Amino Acid Sequence|Hexuronic Acids|Alginate|Models, Molecular|Catalytic Domain|Glucuronic Acid|Bacterial Proteins 23 Pl15 31448186 3 Biotech 2019 PMC6691017 10.1007/s13205-019-1857-7 0 0 0 0 Female|Animals|DNA polymerase zeta|*Catalytic Domain|*Palaemonidae|*DNA-Directed DNA Polymerase|Arthropod Proteins|Amino Acid Sequence|Base Sequence|RNA Interference|Gene Expression Regulation, Developmental|Ovary|Cloning, Molecular 23 Pl15 31426338 Int J Mol Sci 2019 PMC6720513 10.3390/ijms20163995 0 0 0 0 23 PLA2G7 31875617 Int Heart J 2019 10.1536/ihj.19-240 0 0 0 376 Humans|Adult|*Independent Living|*Biomarkers|Lipoprotein-Associated Phospholipase A(2)|Risk Factors|C-Reactive Protein|Myocardial Infarction|Stroke|Proportional Hazard Model|Predictive Value of Tests|Prognosis 241 PLA2G7 31841756 Int. Immunopharmacol. 2019 10.1016/j.intimp.2019.106079 0 0 0 376 *Angioedemas, Hereditary|C1-Inhibitor Protein|Hereditary Angioedema Types I and II|Bradykinin|Disease Progression|Case-Control Studies 241 PLA2G7 31822574 Neurology 2019 10.1212/WNL.0000000000008733 0 1 0 376 Clopidogrel|Ischemic Attack, Transient|Platelet Aggregation Inhibitors|Aspirin|Stroke|Constriction, Pathologic|Recurrence|Drug Therapy, Combination|Polyesters 241 PLA2G7 31802883 Vasc Health Risk Manag 2019 PMC6830380 10.2147/VHRM.S217904 0 1 0 376 Animals|Diabetes Mellitus, Type 2|darapladib|Benzaldehydes|Oximes|1-Alkyl-2-acetylglycerophosphocholine Esterase|Phospholipase A2 Inhibitors|Atherosclerosis|Inflammation|Diabetes Mellitus, Experimental|Biomarkers|Polyesters 241 PLA2G7 31801287 Int J Mol Sci 2019 PMC6929091 10.3390/ijms20236049 1 0 0 376 Humans|*Sepsis|Multiple Organ Dysfunction Syndrome|Inflammation|*Immune System Phenomena|Blood Coagulation|Biologics 241 PLA2G7 31788357 PeerJ 2019 PMC6883954 10.7717/peerj.8079 0 0 0 376 Female|Pregnancy|Sheep|Animals|*Litter Size|Breeding|Gene Frequency|Genotype|Polymorphism, Single Nucleotide|Fertility|China 241 PLA2G7 31741711 Oncotarget 2019 PMC6849651 10.18632/oncotarget.27294 1 0 0 376 Humans|Male|*Prostatectomy|*Prostate|Prostate Cancer|Transcriptional Regulator ERG|*Disease Progression|Neoplasm Recurrence, Local|Biomarkers, Tumor|*Seminal Vesicles|Trans-Activators 241 PLA2G7 31588660 J Magn Reson Imaging 2019 10.1002/jmri.26945 0 0 0 376 Humans|Male|*Prostate Cancer|*Magnetic Resonance Imaging|Prostate-Specific Antigen|Prostate|Image-Guided Biopsy|*Machine Learning|Risk Assessment 241 PLA2G7 31489677 Lipids 2019 10.1002/lipd.12191 0 2 0 376 *Lipoprotein(a)|*Adiponectin|*Phospholipase|1-Alkyl-2-acetylglycerophosphocholine Esterase|Cholesterol, LDL|*Phospholipases A|Coronary Artery Disease|*Energy Intake|Cardiovascular Diseases|Risk Factors|Biomarkers 241 PLA2G7 31266078 Thromb. Haemost. 2019 10.1055/s-0039-1692681 0 1 0 376 Humans|*Aspirin|*Thromboxane-A Synthase|Platelet Function Tests|Platelet Aggregation|Platelet Aggregation Inhibitors|Thromboxane B2|PTGS1 protein, human|Cyclooxygenase 1|Blood Platelets|Receptors, Thromboxane A2, Prostaglandin H2|Arachidonic Acid|Coronary Artery Disease|Cardiovascular Diseases|MicroRNAs|PLA2G6 protein, human|Group VI Phospholipases A2 241 PLA2G7 31236414 Biomed Res Int 2019 PMC6545803 10.1155/2019/8642784 0 1 0 376 *1-Alkyl-2-acetylglycerophosphocholine Esterase|*Risk Factors|*Stroke|Brain Ischemia|Biomarkers|Time Factors 241 PLA2G7 31131629 J. Cardiovasc. Pharmacol. Ther. 2019 10.1177/1074248419852955 1 1 0 376 *Niacin|Cholesterol, HDL|Hypolipidemic Agents|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Simvastatin|Cholesterol, LDL|Ezetimibe|Anticholesteremic Agents|Triglycerides|Lipoprotein(a)|Cardiovascular Diseases|Drug Therapy, Combination|Polyesters 241 PLAC1 31791163 J Obstet Gynaecol 2019 10.1080/01443615.2019.1674263 0 0 0 109 Pregnancy|Humans|Female|*Abortion, Habitual|Embryo Implantation|*Pregnancy Proteins|Infertility, Female|Fertilization in Vitro|Biomarkers|Placenta|PLAC1 protein, human 91 PLAC1 31689783 Medicine (Baltimore) 2019 PMC6946281 10.1097/MD.0000000000017676 0 5 0 109 Humans|Female|Pregnancy|*Pre-Eclampsia|PLAC1 protein, human|Pregnancy Proteins|Placenta|Trophoblasts|Cell Movement|Cell Proliferation|RNA, Small Interfering|Signal Transduction|Cell Line 91 PLAC1 31165204 Cancer Immunol. Immunother. 2019 10.1007/s00262-019-02350-8 1 0 0 109 Humans|Male|Pregnancy|PLAC1 protein, human|*Immunotherapy|Pregnancy Proteins|Antigens, Neoplasm|Placenta|Cell Line, Tumor|Prostate Cancer|Testis 91 PLAC1 30932401 Exp. Oncol. 2019 1 0 0 109 Humans|Mice|Pregnancy|Female|Animals|PLAC1 protein, human|Pregnancy Proteins|*Cancers|Placenta|*Cell Lines|PLAC1 protein, mouse 91 PLAC1 30628705 Oncol. Rep. 2019 PMC6365708 10.3892/or.2019.6955 0 0 0 109 Humans|PLAC1 protein, human|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Oncogenes|*Oncogenesis|Pregnancy Proteins|*Neoplastic Processes|*Cell Line|Medical Oncology|Interior Design and Furnishings|Regret|Cell Proliferation 91 PLCL1 31848144 Ann. Rheum. Dis. 2019 10.1136/annrheumdis-2019-215533 0 0 0 51 40 PLCL1 31131187 Adv Sci (Weinh) 2019 PMC6523368 10.1002/advs.201801862 3 0 0 51 40 PLIN4 31537618 Mol. Cancer Res. 2019 10.1158/1541-7786.MCR-19-0264 1 0 0 44 Humans|*Triple-Negative Breast Cancer|Drug Resistance, Neoplasm|Doxorubicin|Antineoplastic Agents|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Xenograft Model Antitumor Assays|Neoadjuvant Therapy|*Phenotype|Cohort Studies|PLIN4 protein, human|Perilipin-4 52 PLIN4 31281445 Exp Ther Med 2019 PMC6580107 10.3892/etm.2019.7633 1 4 0 44 *Ketamine|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Profiling|Databases, Genetic|Computational Biology|*Antidepressive Agents|Transcriptome|Gene Expression Regulation, Neoplastic|mRNA 52 PLIN4 31218328 Sheng Li Xue Bao 2019 0 0 0 44 Rats|Animals|*Lipid Droplets|*Colforsin|*Rats, Sprague-Dawley|Perilipin|*Adipocytes|Lipolysis|Protein, PLIN2|Lipid Metabolism|Carrier Proteins|Phosphoproteins|Membrane Proteins|Lipase|Proteins, Perilipin|Cell Differentiation|Free Fatty Acids|Triglycerides|Plin2 protein, rat|Plin1 protein, rat 52 PLIN4 31210354 J. Cell. Physiol. 2019 10.1002/jcp.28972 2 0 0 44 Humans|*Adipogenesis|*Mesenchymal Stem Cells|*Lipid Droplets|MIRN675 microRNA, human|*RNA, Micro|MIRN1908 microRNA, human|Transcriptome Profiling|Cell Differentiation|Adipocytes|Messenger RNA|Oligonucleotide Array Sequence Analysis|Osteogenesis|Transcriptome 52 PLIN4 31134678 J. Cell. Biochem. 2019 10.1002/jcb.29020 2 0 0 44 Humans|Mice|Animals|*Transcriptome|*Sevoflurane|*Neuropathology|*Alzheimer Disease|Neurodegenerative Diseases|*Transcriptome Analysis|Gene Ontology|Signal Transduction|Upregulation|Metabolic Pathways|Computational Biology|Downregulation|c-jun N-Terminal Kinase|FOXF1 protein, human|Forkhead Transcription Factors|LRG1 protein, human|Glycoproteins 52 PLIN4 30765794 Sci Rep 2019 PMC6375979 10.1038/s41598-019-38622-7 1 0 0 44 Swine|Animals|Bayes Theorem|*Genome|*Genomics|Acids, Fatty|Meat|Fatty Acids, Monounsaturated|Phenotype|Fatty Acids, Unsaturated|Adipogenesis 52 PLVAP 31873116 Sci Rep 2019 PMC6928218 10.1038/s41598-019-56075-w 2 0 0 168 Humans|*Blood-Brain Barrier|ABCG2 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 2|*Endothelial Cells|Glycogen Synthase Kinase 3|Neoplasm Proteins|*Brain|*Biological Transport|*Cell Line|beta Catenin|*Catenins|Wnt Signaling Pathway|ATP Binding Cassette Transporter, Subfamily B, Member 1|*Cultured Cells|Gene Expression Regulation|Permeability|RNA, Messenger|*Phenotype 100 PLVAP 31759628 Biochem. 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Heart J. 2019 PMC6685329 10.1093/eurheartj/ehz305 7 0 0 168 Humans|Mice|Animals|*Endothelial Cells|*Myocardial Infarction|*Neovascularization, Pathologic|Myocardium|*Transcriptome Analyses|Neovascularization, Physiologic|Myocytes, Cardiac|Cells, Cultured|Regeneration|*B-Lymphocytes|Endothelium|Signal Transduction 100 PLVAP 31155175 Transplant. Proc. 2019 10.1016/j.transproceed.2019.01.128 1 0 0 168 *Kidney Transplantation|Graft Rejection|Isoantibodies|Blood Group Incompatibility|ABO Blood-Group System|Transplantation, Homologous 100 PLVAP 31077000 Neurotox Res 2019 10.1007/s12640-019-00054-6 2 0 0 168 Humans|*Adherens Junctions|*Blood-Brain Barrier|*Gastrointestinal Microbiome|*Schizophrenia|Schizophrenic Psychology|Tryptophan|Neuropsychological Tests|CDH1 protein, human|E Cadherin|*Biological Transport|Case-Control Studies|Antigens, CD|Psychosis 100 PLVAP 31026444 Eur. J. Pharmacol. 2019 10.1016/j.ejphar.2019.04.035 0 1 0 168 Animals|Rats|*Choroidal Neovascularization|Diabetic Retinopathy|Vascular Endothelial Growth Factor A|Macular Edema|*Monkeys|Endothelial Cells|*Rats, Sprague-Dawley|Blood-Retinal Barrier|*Carrier Proteins|Retina|*Laser|Injection, Intravitreal|Retinal Diseases|Membrane Proteins 100 PLVAP 30964206 Hepatology 2019 10.1002/hep.30655 6 0 0 168 Mice|Animals|*Growth Differentiation Factor 2|*Endothelial Cell|Proteomics|ACVRL1 protein, human|Activin Receptors, Type II|*Liver Cirrhosis|*Liver|*Hepatocytes|Activin Receptors, Type I|*Protective Agents|Hepatic Stellate Cells|Telangiectasia, Hereditary Hemorrhagic|Signal Transduction|Cell Differentiation|*Cell Membrane Structures|Stab1 protein, mouse|Cell Adhesion Molecules, Neuronal|Stab2 protein, mouse 100 PLVAP 30954526 Biochim Biophys Acta Gen Subj 2019 10.1016/j.bbagen.2019.04.001 0 0 0 168 Mice|Animals|*Endothelial Cells|*Membrane Proteins|*Sphingosine-1-Phosphate Receptors|Sphingosine|Receptors, Lysosphingolipid|*Cell Membrane|Signal Transduction 100 PLVAP 30932814 Elife 2019 PMC6481993 10.7554/eLife.43818 9 0 0 168 Animals|Mice|*Subfornical Organ|Endothelial Cells|Blood-Brain Barrier|beta Catenin|Capillary Permeability|*Catenins|Wnt Signaling Pathway|Circumventricular Organs|*Homeostasis|Central Nervous System|Zebrafish 100 PLVAP 30854484 Commun Biol 2019 PMC6405929 10.1038/s42003-019-0337-2 2 10 0 168 Mice|Animals|*Caveolae|Bleomycin|Idiopathic Pulmonary Fibrosis|Lungs|Disease Models, Animal|*Drug Delivery Systems|RNA, Messenger 100 PLXDC2 31271701 J. Thromb. Haemost. 2019 10.1111/jth.14562 0 0 0 107 *Genome-Wide Association Study|Factor V|*Blood Coagulation|Factor V Deficiency|*Blood Coagulation Tests|Polymorphism, Single Nucleotide|Mutation 29 PLXDC2 31130920 Front Endocrinol (Lausanne) 2019 PMC6509200 10.3389/fendo.2019.00283 1 2 0 107 29 PLXDC2 30901387 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.18-25922 2 0 0 107 *Glaucoma, Primary Open Angle|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Alleles|Genotype|Case-Control Studies 29 PLXDC2 30606130 BMC Genomics 2019 PMC6318962 10.1186/s12864-018-5379-1 2 0 0 107 Animals|*Genome-Wide Association Study|*Ducks|Quantitative Trait Loci|*Body Size|Phenotype|Genotype|Body Weight|Meat|Body Composition|Polymorphism, Single Nucleotide|Asia 29 PM20D1 31795606 Int Neurourol J 2019 PMC6905210 10.5213/inj.1938196.098 2 2 0 15 *Methyl-CpG-Binding Protein 2|*Alzheimer Disease|Rett Syndrome|Brain|Neurons|Neuroglia|Cellular Senescence|Astrocytes|Microglia|Apoptosis 27 PM20D1 31706267 Mol. Med. 2019 PMC6842480 10.1186/s10020-019-0113-2 2 0 0 15 *Transcriptome|*Prognosis|*Transcriptome Analysis|*Pancreatic Cancer|Tumor Markers|Gene Regulatory Networks|Protein Interaction Maps|Gene Ontology|Computational Biology|Gene Expression Regulation, Neoplastic 27 PM20D1 31659023 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6859347 10.1073/pnas.1913199116 3 0 0 15 Mice|Animals|Humans|3T3-L1 Cells|Thiazolidinediones|PPAR gamma|Rosiglitazone|Hypoglycemic Agents|Adipose Tissue|Transcription Factors|Adipocytes, White|Genetic Variation|PM20D1 protein, mouse|Amidohydrolases 27 PM20D1 31587987 Cell Chem Biol 2019 PMC6874721 10.1016/j.chembiol.2019.09.009 1 0 0 15 Mice|Animals|*Metabolomics|Mass Spectrometry|Metabolome|Chromatography, Liquid|Homeostasis 27 PM20D1 31568785 Eur. J. Pharmacol. 2019 10.1016/j.ejphar.2019.172708 0 3 0 15 Mice|Animals|*Adiposity|*Obesity|Adipose Tissue, Brown|Adipose Tissue, White|*Body Weight|Diet, High-Fat|Thermogenesis|Adipogenesis|Insulin Resistance|Energy Intake|Energy Metabolism|miRNAs|Upregulation|PM20D1 protein, mouse|Amidohydrolases 27 PM20D1 31166810 Epigenomics 2019 10.2217/epi-2018-0136 1 1 0 15 27 PM20D1 30681197 Pediatr Allergy Immunol 2019 10.1111/pai.13023 2 0 0 15 Humans|Child, Preschool|Infant|Child|*Respiratory Sounds|*Epigenome|*B-DNA|*Saliva|CpG Islands|DNA Methylation|Epigenesis, Genetic|Asthma|Epigenetics|Genome-Wide Association Study 27 pmel 31772839 PeerJ 2019 PMC6875393 10.7717/peerj.8077 0 1 0 350 Sheep|Animals|*Transcriptome Profiling|Skin Pigmentation|Hair Color|Transcriptome|Breeding|Skin 674 pmel 31700227 Mol. Vis. 2019 PMC6817737 0 7 0 350 *Epithelial-Mesenchymal Transition|GREM1 protein, human|*Intercellular Signaling Peptides and Proteins|Signal Transduction|Retinal Pigment Epithelium|Epithelial Cells|Gene Expression Regulation|Cell Line 674 pmel 31547237 Int J Mol Sci 2019 PMC6769613 10.3390/ijms20184509 1 0 0 350 Mice|Animals|*Immunological Synapses|*T-Lymphocytes, Cytotoxic|GJA1 protein, human|*Connexin 43|*Gap Junctions|*Melanoma|*Connexins|Cytotoxicity, Immunologic|MART-1 Antigen|PMEL protein, human|gp100 Melanoma Antigen|Natural Killer Cell|*Antineoplastic Agents|Cell Communication|Cell Line, Tumor|B 43|*Peptides 674 pmel 31466995 Cancer Immunol Res 2019 10.1158/2326-6066.CIR-18-0873 3 0 0 350 Mice|Animals|CTLA4 protein, human|*CTLA-4 Antigen|*Programmed Cell Death 1 Receptor|Lymphocytes, Tumor-Infiltrating|CD8-Positive T-Lymphocytes|Immunotherapy|Tumor|Antibodies, Monoclonal|Adoptive Transfer|Mice, Inbred C57BL|Tumor Microenvironment|Cell- and Tissue-Based Therapy|Icos protein, mouse|Inducible T-Cell Co-Stimulator Protein 674 pomp 31827472 Front Immunol 2019 PMC6890838 10.3389/fimmu.2019.02756 2 0 0 118 *Proteasome Endopeptidase Complex|*Syndrome|*Unfolded Protein Response|eIF-2 Kinase|Endoplasmic Reticulum Stress|Interferon Type I|*Cytoplasm 588 pomp 31756029 Mol. Plant Pathol. 2019 PMC6913204 10.1111/mpp.12880 0 0 0 118 Animals|*Ubiquitin C|*Tylenchoidea|Plant Immunity|Potato|Ubiquitin Ligase E3|Ubiquitination|Plant Diseases|Arabidopsis|*Gene Expression|Proteins 588 pomp 31742837 Cancer Sci. 2019 PMC6942428 10.1111/cas.14244 2 0 0 118 Humans|Mice|Animals|*Proteasome Endopeptidase Complex|*Ubiquitin|*Proteolysis|NFE2L2 protein, human|*NF-E2-Related Factor 2|Adenocarcinoma|Pancreatic Carcinoma|Pancreatic Neoplasms|Oxidative Stress|Basic-Leucine Zipper Transcription Factors|TP53 protein, human|Tumor Suppressor Protein p53|*Cytoplasm|Gene Expression Regulation 588 POTEE 31791268 BMC Med. Genet. 2019 PMC6889628 10.1186/s12881-019-0923-7 0 0 0 39 Humans|Male|*Computational Biology|*Prostate Cancer|PTEN protein, human|*PTEN Phosphohydrolase|*Mutation|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Databases, Genetic|Protein Interaction Mapping|Transcriptome|Signal Transduction 20 POTEE 31723122 Cell Death Dis 2019 PMC6853991 10.1038/s41419-019-2046-7 1 4 0 39 Humans|*Tumors, Colorectal|*Signal Transduction|Tumorigenesis|Cell Transformation, Neoplastic|Cell Proliferation|Biomarkers, Tumor|Cell Movement|Oncogene|Cell Line, Tumor|*Colonic Neoplasms|Upregulation 20 POTEE 31124977 Medicine (Baltimore) 2019 PMC6571259 10.1097/MD.0000000000015796 1 0 0 39 *Intervertebral Disc Degeneration|Phosphatidylinositol 3-Kinases|Gene Ontology|Bioinformatics|miRNAs|Gene Expression Profiling|*Data Mining|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Microarray Analysis|*Gene Expression|Signal Transduction 20 pou2f3 31783921 Vet. Res. 2019 PMC6884896 10.1186/s13567-019-0722-3 0 0 0 144 Sheep|Animals|*Haemonchus|Haemonchiasis|*Anthelmintics|Parasite Egg Count|Abomasum|Sheep Diseases|Nematode Infections|Gastrointestinal Diseases|*Disease Susceptibility|Nematoda|*Sheep, Domestic|Feces|Eosinophils|Breeding|Humoral Immunity|France 50 pou2f3 31324758 Nat Commun 2019 PMC6642156 10.1038/s41467-019-11153-5 0 1 0 144 Small Cell Lung Carcinoma|*Pulmonary Cancer|ASCL1 protein, human|Basic Helix-Loop-Helix Transcription Factors|NeuroD protein|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Transcription Factors|*Carcinoma, Neuroendocrine|Cell Proliferation|Nerve Tissue Proteins|Lung 50 pou2f3 31182574 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6601016 10.1073/pnas.1900251116 4 1 0 144 Mice|Animals|Tumor Stem Cells|Intracellular Signaling Peptides and Proteins|Protein-Serine-Threonine Kinases|Gene Expression Regulation, Neoplastic|Intestinal Neoplasms|Cell Line, Tumor|Biomarkers, Tumor|Intestines 50 pou2f3 30926931 Nat. Rev. Cancer 2019 PMC6538259 10.1038/s41568-019-0133-9 17 0 0 144 Humans|Mice|Animals|*Small Cell Lung Carcinoma|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|YAP1 (Yes-associated) protein, human|Adaptor Proteins, Signal Transducing|Phosphoproteins|Signal Transduction|Gene Knockdown Techniques|Nerve Tissue Proteins|Pou2f3 protein, mouse|Octamer Transcription Factors 50 POU3F1 31791948 Biol Open 2019 PMC6899006 10.1242/bio.046367 1 0 0 285 Germ Layers|Nanog Homeobox Protein|Pluripotent Stem Cells|Cell Differentiation|Embryonic Stem Cells|Homeodomain Proteins|Octamer Transcription Factor-3|Cell Lineage|Gene Expression Regulation, Developmental|Transcription Factors|Germ Cells 138 POU3F1 31606837 Neurochem. Res. 2019 10.1007/s11064-019-02885-3 0 4 0 285 Rats|Animals|geldanamycin|Lactams, Macrocyclic|*HSP90 Heat-Shock Proteins|Benzoquinones|ERBB2 protein, human|Receptor, ErbB-2|*Schwann Cells|*Cell Differentiation|Signal Transduction|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Phosphorylation|Protein Transport|Molecular Chaperones|Myelin|Gab1 protein, rat|Phosphoproteins 138 POU3F1 31212703 Cancers (Basel) 2019 PMC6627474 10.3390/cancers11060810 0 0 0 285 *Octamer Transcription Factor-6|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Genotoxic Stress|POU2F1 protein, human|Octamer Transcription Factor-1|Transcription Factors|Host Cell Factor C1|Tumor Suppressor Protein p53|Transcription Factor POU|G2 Cell Cycle Arrest|DNA 138 POU3F1 31005627 Neurosci Biobehav Rev 2019 10.1016/j.neubiorev.2019.04.010 7 0 0 285 Humans|Child|*Depression|*Epigenesis, Genetic|DNA Methylation|tacrolimus binding protein 5|Tacrolimus Binding Proteins|*Epigenetics|Receptors, Glucocorticoid|Depressive Disorder, Major|SLC6A4 protein, human|Serotonin Plasma Membrane Transport Proteins|Stress, Psychological|Child Abuse|Signal Transduction|SKA2 protein, human|Chromosomal Proteins, Non-Histone 138 POU3F3 31796600 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6929682 10.1073/pnas.1904006116 0 0 0 131 *Brain Mapping|Vesicular Glutamate Transport Protein 2|Vesicular Glutamate Transport Protein 1|*Brain|Neurons|Glutamic Acid|*Indusium Griseum 67 POU3F3 31396351 Am J Transl Res 2019 PMC6684896 1 0 0 131 Humans|*Muscle, Smooth, Vascular|Percutaneous Coronary Intervention|*Coronary Restenosis|*Myocytes, Smooth Muscle|*Signal Transduction|Kruppel-Like Transcription Factors|Cell Differentiation|Cell Proliferation|MicroRNAs|Aorta|Phenotype|Cells, Cultured|*Stent|POU3F3 protein, human|POU Domain Factors 67 POU3F3 31303265 Am. J. Hum. Genet. 2019 PMC6698880 10.1016/j.ajhg.2019.06.007 2 0 0 131 Child|Humans|*Transcriptional Activation|*Disorder, Neurodevelopmental|Intellectual Disability|Mutation, Missense|Developmental Disabilities|Heterozygote|Exome|Phenotype|Gene Expression Regulation|Mutation|Amino Acid Sequence|Forkhead Transcription Factors|POU3F3 protein, human|POU Domain Factors 67 POU3F3 31252264 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109133 3 1 0 131 Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|Sp1 protein, human|*Sp1 Transcription Factor|MicroRNAs|Neoplasm Invasiveness|Up-Regulation|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Tumorigenesis|Gene Knockdown Techniques|HeLa Cells|Oncogene|3' UTR|Disease Progression|FOXD1 protein, human 67 POU3F3 30843771 Biosci. Biotechnol. Biochem. 2019 10.1080/09168451.2019.1588097 2 4 0 131 Humans|*RNA, Long Noncoding|*Triple-Negative Breast Cancer|CASP9 protein, human|*Caspase 9|*Apoptosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Upregulation|Cell Line, Tumor|POU Domain Factors|Transcriptional Activation|POU3F3 protein, human 67 POU3F3 30602452 Biosci. Rep. 2019 PMC6350041 10.1042/BSR20181632 3 8 0 131 Humans|*RNA, Long Noncoding|*Up-Regulation|*Nasopharyngeal Carcinoma|Follow-Up Studies|*Cell Migration|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Transforming Growth Factor beta1|Prognosis|Downregulation|*Transcriptional Activation|*Neoplastic Processes|*Transforming Growth Factor|Nasopharyngeal Neoplasms|POU3F3 protein, human|POU Domain Factors 67 POU3F4 31786483 Int. J. Pediatr. Otorhinolaryngol. 2019 10.1016/j.ijporl.2019.109790 0 0 0 75 Male|Humans|*Siblings|Italy|Progressive hearing loss stapes fixation|Hearing Loss, Sensorineural|Hearing Loss, Conductive|Genetic Diseases, X-Linked|POU Domain Factors|Hearing Loss|Deafness|Ear, Inner|Pedigree|Mutation, Missense|*Models, Molecular|Mutation|POU3F4 protein, human 154 POU3F4 31620696 Turk Arch Otorhinolaryngol 2019 PMC6779105 10.5152/tao.2019.4320 0 0 0 75 Child|Humans|*Hearing Loss|Connexin 26|Connexins|Deafness|Hearing Loss, Sensorineural|Gene Frequency|Mutation 154 POU3F4 31440883 Pediatr Radiol 2019 10.1007/s00247-019-04497-z 2 1 0 75 Male|Humans|*Stapes|Hypothalamic hamartomas|*Ear, Inner|*Hypothalamic Diseases|*Hamartoma|Hearing Loss, Sensorineural|Stapes Surgery|Deafness|*Incus|POU Domain Factors|*Ossicular Prosthesis|*Syndrome|*Diverticula|*Genes, X-Linked|Magnetic Resonance Imaging|POU3F4 protein, human 154 POU3F4 31177298 Neuroradiology 2019 10.1007/s00234-019-02230-z 1 0 0 75 Humans|Ear, Inner|Hearing Loss, Sensorineural|Stapes Surgery|*Genes, X-Linked|Deafness|Hearing Loss, Conductive|Cochlea|POU Domain Factors|Mutations|Tomography, X-Ray Computed|*Hypothalamus|POU3F4 protein, human 154 POU3F4 31131597 Balkan Med J 2019 PMC6636654 10.4274/balkanmedj.galenos.2019.2019.4.66 0 0 0 75 Humans|*Ear, Inner|Labyrinth Diseases|Deafness|Hearing Loss, Sensorineural|Hearing Loss|Tomography, X-Ray Computed 154 POU3F4 31063410 Genet Test Mol Biomarkers 2019 10.1089/gtmb.2018.0296 0 0 0 75 154 POU3F4 30874365 Anat Rec (Hoboken) 2019 10.1002/ar.24115 0 0 0 75 Humans|Animals|*Zebrafish|*Genes, X-Linked|Quality of Life|Nonsyndromic sensorineural hearing loss|*Hearing Loss, Sensorineural|PRPS1 protein, human|Ribose-Phosphate Pyrophosphokinase|Deafness, X-Linked 1|*Genetic Diseases, X-Linked|Nonsyndromic Deafness|Deafness|Hearing Loss|Ear, Inner|Mutations|Pedigree|Mutations, Missense|Phenotype|Hearing 154 POU3F4 30733538 Sci Rep 2019 PMC6367484 10.1038/s41598-018-38245-4 1 0 0 75 Child|Humans|Vietnam|*Mutation|*Hearing Loss|DNA Mutational Analysis|Connexins|Chinese|Deafness|Massively Parallel Sequencing|Pedigree|Alleles|Indochina|POU3F4 protein, human|POU Domain Factors 154 POU6F1 31665313 J. Biochem. 2019 10.1093/jb/mvz088 0 2 0 30 Humans|AURKA protein, human|*Aurora Kinase A|*Phosphorylation|*Muscle Development|Aurora Kinases B|Mitosis|*Cell Differentiation|Transcription Factor|Protein Kinases|Gene Expression Regulation|HEK293 Cells|Muscle, Skeletal 34 PPP1R3A 31235787 Nat Commun 2019 PMC6591478 10.1038/s41467-019-10591-5 2 0 0 909 Humans|Mice|Animals|*Gene Regulatory Networks|*Heart Failure|Cardiomyocyte|Gene Expression Profiling|Sequencing, RNA|Signal Transduction|Disease Models, Animal|Gene Expression|Metabolic Pathway|PPP1R3A protein, human|Phosphoprotein Phosphatases 40 PPP1R3A 31185731 Circulation 2019 PMC6699925 10.1161/CIRCULATIONAHA.119.039642 2 17 0 909 *Atrial Fibrillation|*Protein Phosphatase 1|Sarcoplasmic Reticulum|Ryanodine Receptor Calcium Release Channel|Myocytes, Cardiac|Calcium-Calmodulin-Dependent Protein Kinase Type 2|Calcium 40 PRB2 31687685 Phys Chem Chem Phys 2019 10.1039/c9cp05103a 0 0 0 68 *Microbubbles|*Motion|Ultrasonics|Acoustic|Ultrasonography|Contrast Media 207 PRB2 31297036 Cancer Cell Int. 2019 PMC6599314 10.1186/s12935-019-0884-0 0 0 0 68 Humans|*Triple-Negative Breast Cancer|*Prognosis|RNA, Long Noncoding|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Biomarkers, Tumor|RNA, Messenger|Bioinformatics 207 PRB2 31203147 Transl Oncol 2019 PMC6581966 10.1016/j.tranon.2019.03.006 1 0 0 68 Humans|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Cancer|SMAD4 protein, human|Smad4 Protein|Anophthalmia with pulmonary hypoplasia|*Anophthalmos|*Microphthalmos|Mutations|Sequencing, Next-Generation|Tumor Suppressor Protein p53|TGFBR1 protein, human|TGFBR1|*Diabetes Mellitus|Cohort Studies 207 PRB2 30973677 Head Neck 2019 10.1002/hed.25754 0 0 0 68 Humans|*Platinum|*Head and Neck Neoplasms|*Chemoradiotherapy|Squamous Cell Carcinoma of Head and Neck|Endonucleases|*Glutathione S-Transferase pi|Carcinoma, Squamous Cell|DNA-Binding Proteins|DNA Repair|Polymorphism, Single Nucleotide|ERCC1 protein, human|GSTP1 protein, human 207 PRB2 30747498 2019 10.1002/art.40857 1 0 0 68 *Cartilage, Articular|*Mitochondria|Osteoarthritis, Knee|Chondrocytes|*Apoptosis|DNA Methylation|Case-Control Studies|*Biochemical Phenomena|DNA, Mitochondrial 207 PRB2 30710075 Nat Commun 2019 PMC6358624 10.1038/s41467-018-08272-w 10 0 0 68 Humans|Haplotype|African Continental Ancestry Group|Genetics, Population|*Genetic Drift|Human Migration|Gene Flow|European Continental Ancestry Group|Structure, Genetic|DNA, Mitochondrial|Europe|Ethnic Groups|Geography|Spain 207 PRB2 30616395 Expert Opin Drug Discov 2019 10.1080/17460441.2019.1559148 1 0 0 68 Humans|Animals|Pluripotent Stem Cells|*Retinal Diseases|Cell Differentiation|Retinal Pigment Epithelium|Macular Degeneration|Induced Pluripotent Stem Cells|Stem Cell Transplantation|Epithelial Cells|Retinal Pigments 207 PRDM8 31037071 Front Immunol 2019 PMC6476283 10.3389/fimmu.2019.00791 1 31 0 41 25 PRICKLE2 31691285 J. Cell. Physiol. 2019 10.1002/jcp.29393 0 0 0 83 Humans|*DNA Methylation|*Peripheral Nerve Injuries|Epigenesis, Genetic|Nerve Regeneration|Gene Ontology|Injury, Spinal Cord|Protein Interaction Maps|*Gene Expression Regulation|Spinal Cord|Gene Expression Profiling|Trauma, Nervous System|Central Nervous System|NUMBL protein, human|Intracellular Signaling Peptides and Proteins 50 PRICKLE2 30814664 Sci Rep 2019 PMC6393536 10.1038/s41598-019-39642-z 0 26 0 83 Animals|Humans|*Cell Polarity|HEK293 Cells|Autism Spectrum Disorder|PDLIM4 protein, human|LIM Domain Proteins|DNA-Binding Proteins|Nerve Tissue Proteins|Membrane Proteins|Carrier Proteins|Drosophila|Signal Transduction|*Transcription Factors|2,5-dichloro-4-bromophenol|*Chlorophenols|VANGL2 protein, human|Intracellular Signaling Peptides and Proteins|prickle protein, Drosophila 50 PRIMA1 31845320 Int. J. Cancer 2019 PMC7297651 10.1002/ijc.32830 2 0 0 187 Humans|Female|mortalin|*Tumor Suppressor Protein p53|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*HSP70 Heat-Shock Proteins|Drug Resistance, Neoplasm|2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one|Bridged Bicyclo Compounds, Heterocyclic|Cell Line, Tumor|Apoptosis|(((4-nitrophenyl)amino)(2,2,4,4-tetramethyl thiochroman-6-yl)amino) methane-1-thione|Chromans|Thiones|Aza Compounds|Quinuclidines 67 PRIMA1 31406157 Sci Rep 2019 PMC6691113 10.1038/s41598-019-48186-1 0 0 0 187 Humans|*Carotid Intima-Media Thickness|*Genetic Linkage|*Atherosclerosis|Quantitative Trait Locus|Carotid Artery Diseases|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Pedigree|*Hispanic Americans|Phenotype|Sequence Analysis, DNA|Exons|PRIMA1 protein, human|Membrane Proteins|Nerve Tissue Proteins|SPATA7 protein, human 67 PRM1 31793700 Andrologia 2019 10.1111/and.13483 0 0 0 6 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Testis|*Semen|*Spermatogenesis|Sperm Retrieval|Spermatozoa|*Biomarkers|Real Time Polymerase Chain Reaction|mRNA 379 PRM1 31785643 Anim. Reprod. Sci. 2019 10.1016/j.anireprosci.2019.106203 0 0 0 6 Cattle|Male|Animals|Humans|*Sperm|*Fertility|Acrosome|Semen Analysis|Sperm Motility|protamine 2|Protamines|DNA Fragmentation|*Cell Nucleus|Chromatin|Flow Cytometry|Cell Membrane 379 PRM1 31762067 Andrologia 2019 10.1111/and.13484 0 0 0 6 Male|Humans|Adult|*Semen|*DNA Methylation|*Sperm|protamine 2|*Protamines|DNA Fragmentation|Semen Analysis|Infertility, Male|Fertility|DNA|*Bodily Secretions 379 PRM1 31692026 Andrologia 2019 10.1111/and.13450 0 5 0 6 Male|Animals|Mice|*Zinc Oxide|*Hyssopus Plant|*BALB C Mice|*Prostate|*Spermatogenesis|*Testis|Green Chemistry Technology|Metal Nanoparticles|Plant Leaves|Cell Survival|Plant Extracts|*Plant Oils|Tnp2 protein, mouse|Nuclear Proteins|Adam3 protein, mouse|Membrane Glycoproteins|ADAM Proteins 379 PRM1 31528039 Vet World 2019 PMC6702581 10.14202/vetworld.2019.1101-1107 0 0 0 6 Animals|Male|*Pituitary Adenylate Cyclase-Activating Polypeptide|*Testis|*Epididymis|*Testosterone|*Chickens|Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I|*Testosterone Congeners|RNA, Messenger|Protamines|Plant Extracts 379 PRM1 31492135 Malar. J. 2019 PMC6731556 10.1186/s12936-019-2939-z 0 0 0 6 *Plasmodium vivax|*Antigens, Protozoan|Malaria, Vivax|Malaria Vaccines|Protozoan Proteins|DNA, Protozoan|Polymorphism, Genetic|Genetic Variation|Haplotypes|Sequence Analysis, DNA|Phylogeny|Antigens, Surface|Amino Acid Sequence|Amino Acid Substitution|Polymerase Chain Reaction 379 PRM1 31408151 FEMS Yeast Res. 2019 PMC6736287 10.1093/femsyr/foz059 0 1 0 6 *Methanol|*Pichia|Citrobacter braakii|Gene Expression Regulation, Fungal|Transcription Factors|Fungal Proteins|Promoter Regions, Genetic|*Saccharomycetales|Alcohol Oxidoreductases|Binding Sites 379 PRM1 31330346 Environ. Pollut. 2019 10.1016/j.envpol.2019.06.107 0 2 0 6 Male|Humans|Rats|Animals|*Fluorides|*Haploidy|*Spermatogenesis|Sperm|Testis|Spermatids|Acrosome|DEAD-box RNA Helicases|RNA, Messenger|Downregulation|Drinking Water|TDRD1 protein, human|Carrier Proteins 379 PRM1 31328782 Mol. Hum. Reprod. 2019 10.1093/molehr/gaz043 0 3 0 6 Humans|Male|Animals|Swine|*Haploidy|Spermatogonia|Spermatogenesis|Spermatids|Seminiferous Tubule|Spermatozoa|Testis|Retinoic Acid|Sertoli Cells|Cell Differentiation|Meiosis|Akrosin|Oocytes|*Hematopoiesis|Adult Germline Stem Cells|Adaptor Proteins, Signal Transducing 379 PRM1 31311428 Stem Cells Dev. 2019 10.1089/scd.2019.0026 0 0 0 6 Humans|Male|Mice|Animals|*Exosomes|*Busulfan|Azoospermia, Nonobstructive|*Azoospermia|Stem Cells|Cell Differentiation|Stem Cell Transplantation|Adipocytes|*Spermatogenesis|*B Cells|Wound Healing|Cell Proliferation|Diabetes Mellitus, Experimental|Disease Models, Animal 379 PRM1 31286559 Andrologia 2019 10.1111/and.13367 0 0 0 6 Humans|Male|Case-Control Studies|*Risk Factors|Egypt|Sperm Motility|protamine 2|Protamines|Infertility, Male|Spermatozoa|Single Nucleotide Polymorphisms|Allele|Spermatogenesis|Sperm Count|Promoter Regions, Genetic 379 PRM1 31271729 Exp. Mol. Pathol. 2019 10.1016/j.yexmp.2019.104277 0 0 0 6 Male|Humans|*Prostate|*Monocytes|*Isoforms|*Transcription Factors|*Cell Differentiation|Receptors, Thromboxane A2, Prostaglandin H2|*Receptors, Prostaglandin|Prostate Cancer|*Macrophage|Transcription, Genetic|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Cell Line, Tumor|*Hematopoiesis|*Inflammation|Prostaglandins|FOXP1 protein, human|Repressor Proteins 379 PRM1 31103297 J. Dairy Sci. 2019 10.3168/jds.2018-15680 2 0 0 6 Cattle|Male|Animals|Humans|Y Chromosome|Breeding|Spermatogenesis|Fertility|Male Sterility|Testis|DNA Copy Number Variations|Cell Cycle Proteins 379 PRM1 30959396 Leg Med (Tokyo) 2019 10.1016/j.legalmed.2019.03.007 0 0 0 6 *Semen|*mRNA|*miRNA|*Laundering|*Body Fluids|Forensic Genetics|Blood Stains|Saliva|*Bodily Secretions|Real-Time Polymerase Chain Reaction|Biomarkers 379 PRM2 31785643 Anim. Reprod. Sci. 2019 10.1016/j.anireprosci.2019.106203 0 0 0 108 Cattle|Male|Animals|Humans|*Sperm|*Fertility|Acrosome|Semen Analysis|Sperm Motility|protamine 2|Protamines|DNA Fragmentation|*Cell Nucleus|Chromatin|Flow Cytometry|Cell Membrane 158 PRM2 31783679 Animals (Basel) 2019 PMC6940725 10.3390/ani9121038 0 0 0 108 Male|Humans|Dogs|Animals|Semen Analysis|*Freezing|*Myoinositol|*Sperm|Semen Preservation|Cryopreservation|Sperm Motility|Semen|Acrosome|Reactive Oxygen Species|Dietary Supplements 158 PRM2 31572580 Food Sci Nutr 2019 PMC6766575 10.1002/fsn3.1128 1 0 0 108 Animals|*Methionine|*Cystine|*Diet, Protein-Restricted|*Racemethionine|Amino Acids, Sulfur|Cysteine|Animal Feed|Amino Acids|*Reproduction|China 158 PRM2 31492135 Malar. J. 2019 PMC6731556 10.1186/s12936-019-2939-z 0 0 0 108 *Plasmodium vivax|*Antigens, Protozoan|Malaria, Vivax|Malaria Vaccines|Protozoan Proteins|DNA, Protozoan|Polymorphism, Genetic|Genetic Variation|Haplotypes|Sequence Analysis, DNA|Phylogeny|Antigens, Surface|Amino Acid Sequence|Amino Acid Substitution|Polymerase Chain Reaction 158 PRM2 31489793 Andrology 2019 10.1111/andr.12694 0 0 0 108 Humans|Male|Mice|Animals|bisphenol A|*Spermatozoa|bisphenol B|*Benzhydryl Compounds|*Phenols|Semen Analysis|DNA Fragmentation|Spermatogenesis|Infertility, Male|In Situ Nick-End Labeling|Protamines|Testis|*DNA|Chromatin 158 PRM2 31286559 Andrologia 2019 10.1111/and.13367 0 0 0 108 Humans|Male|Case-Control Studies|*Risk Factors|Egypt|Sperm Motility|protamine 2|Protamines|Infertility, Male|Spermatozoa|Single Nucleotide Polymorphisms|Allele|Spermatogenesis|Sperm Count|Promoter Regions, Genetic 158 PRM2 31103297 J. Dairy Sci. 2019 10.3168/jds.2018-15680 2 0 0 108 Cattle|Male|Animals|Humans|Y Chromosome|Breeding|Spermatogenesis|Fertility|Male Sterility|Testis|DNA Copy Number Variations|Cell Cycle Proteins 158 PRM2 31009948 Hum. Mol. Genet. 2019 PMC6644162 10.1093/hmg/ddz079 4 0 0 108 Male|Mice|Humans|Animals|*Spermatids|*Spermatogenesis|Testis|Spermatocytes|DEAD-box RNA Helicases|mRNA|Gonadotropin|3' UTR|*Phosphorylation|Chromatin Assembly and Disassembly|Mice, Transgenic|Cytoplasm|Proteins|*Mutation|Ddx25 protein, mouse 158 PRM2 30920782 Andrology 2019 10.1111/andr.12610 0 0 0 108 Humans|Cattle|Animals|Male|protamine 2|*Testis|*Protamines|*Spermatozoa|Infertility, Male|Spermatids|Chromatin|Histones|Nuclear Proteins|RNA, Messenger 158 PRM2 30914484 Sci Signal 2019 10.1126/scisignal.aao7232 1 3 0 108 Humans|Male|Mice|Animals|*Sperm Maturation|protamine 2|*Serine|*Protamines|Spermatogenesis|Spermatozoa|Infertility, Male|Sperm Motility|Testis|Histones 158 PRM2 30876814 Reprod Biol 2019 10.1016/j.repbio.2019.03.001 0 0 0 108 Humans|Male|*Protamines|*Histones|*Chromatin|*mRNA|*Sperm|Infertility, Male|Spermiogenesis|Testis|Cell Nucleus 158 PRM2 30847152 Food Sci Nutr 2019 PMC6392826 10.1002/fsn3.918 0 3 0 108 158 PRM2 30810820 Int. J. Legal Med. 2019 10.1007/s00414-019-02027-y 0 0 0 108 Female|*RNAs, Circular|Forensic Genetics|Saliva|Cervix Mucus|*Biomarkers|Semen|Messenger RNA|Body Fluids|Real-Time Polymerase Chain Reaction|Gene Expression Profiling|Menstruation 158 PRM2 30644249 Int J Fertil Steril 2019 PMC6334022 10.22074/ijfs.2019.5650 0 0 0 108 Humans|Male|*Teratozoospermia|Case-Control Studies|Semen Analysis|Iran|Infertility, Male|Sperm|Protamines|Spermatogenesis|Single Nucleotide Polymorphisms|Fertility|Allele Frequency|Genotype|PRM1 protein, human 158 PRM2 30629479 OMICS 2019 10.1089/omi.2018.0155 0 1 0 108 Humans|Male|Mice|Animals|*Epididymis|*Proteomics|Sperm Maturation|Spermatogenesis|Testis|Spermatozoa|Infertility, Male|Fertility 158 PRPH2 31884660 Adv. Exp. Med. Biol. 2019 10.1007/978-3-030-27378-1_81 0 0 0 410 Peripherins|Rod Cell Outer Segment|Retinal Cone Photoreceptor Cells|*Morphogenesis|Retinal Degeneration|Eye Proteins|Membrane Proteins|Nerve Tissue Proteins|Membrane Glycoproteins|Mutation 214 PRPH2 31819643 Cancer Manag Res 2019 PMC6896914 10.2147/CMAR.S222527 0 9 0 410 *Anoikis|*Laryngeal Neoplasms|*Signal Transduction|Protein-Serine-Threonine Kinases|Adaptor Proteins, Signal Transducing|Phosphoproteins|Neoplasm Invasiveness|Cell Proliferation|Cell Line, Tumor|Cell Movement|Transcription Factors|*Cytoskeletal Proteins|Phosphorylation|Gene Expression Regulation, Neoplastic|2,5-dichloro-4-bromophenol|*Chlorophenols 214 PRPH2 31704701 Br J Ophthalmol 2019 PMC7147237 10.1136/bjophthalmol-2019-315086 3 0 0 410 Humans|Animals|Fundus Dystrophy, Pseudoinflammatory, Of Sorsby|*Macular Dystrophies|Retinal Dystrophies|Retina|Genetic Testing|Vision Disorders|Genetic Linkage|Mutation 214 PRPH2 31618092 Ophthalmic Genet. 2019 10.1080/13816810.2019.1678178 0 0 0 410 214 PRPH2 31614793 Genes (Basel) 2019 PMC6826621 10.3390/genes10100792 1 0 0 410 *Retinitis Pigmentosa|Peripherins|Retinal Dystrophies|Pedigree|High-Throughput Nucleotide Sequencing|Mutation 214 PRPH2 31574917 Int J Mol Sci 2019 PMC6801687 10.3390/ijms20194854 0 0 0 410 Humans|*Cone-Rod Dystrophies|*Retinal Dystrophies|*Retinal Cone Photoreceptor Cells|*Retinitis Pigmentosa|Electroretinography|*Phenotype|Retina|Coherence Tomography, Optical|Macular Degeneration|Fundus Oculi|Visual Acuity|Pedigree|Mutation|Cohort Studies 214 PRPH2 31387115 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.18-26415 0 0 0 410 Humans|*Silent Mutation|*Macula Lutea|Retinal Dystrophy|*Phenotype|Electroretinography|*Exon|Fluorescein Angiography|Genes, Recessive|DNA Mutational Analysis|Retina|Homozygote|Pedigree|Tomography, Optical Coherence|Visual Acuity|*Reading Frames|Mutation|CDHR1 protein, human|Nerve Tissue Proteins 214 Prrx1 31758827 Stem Cells 2019 10.1002/stem.3125 0 1 0 589 Mice|Animals|*Bronchioles|*Epithelial Cells|*Signal Transduction|Respiratory Mucosa|Regeneration|*Gene Expression Regulation|Lung|Progenitor Cells|Cell Differentiation|Bone Morphogenetic Proteins|Wound Healing|Cell Proliferation|Transcription Factor|DNA-Binding Proteins 288 Prrx1 31752959 J. Exp. Clin. Cancer Res. 2019 PMC6873584 10.1186/s13046-019-1475-6 3 5 0 589 *Carcinoma, Hepatocellular|*Neoplastic Cells, Circulating|*Down-Regulation|*Liver Neoplasms|Neoplasm Recurrence, Local|CXCL12 protein, human|*Chemokine CXCL12|CXCR4 protein, human|*Receptors, CXCR4|PRRX1 protein, human|*Homeodomain Proteins|*Signal Transduction|Cell Movement|Cell Line, Tumor 288 Prrx2 31880857 J. Cell. Mol. Med. 2019 PMC7011146 10.1111/jcmm.14914 2 0 0 246 Humans|Mice|Animals|*Up-Regulation|*Genes, Homeobox|*Myocardial Infarction|Fibrosis|Myocardium|Fibroblasts|WNT5A protein, human|*Wnt-5a Protein|Myofibroblasts|Signal Transduction|Transforming Growth Factor beta1|Cell Differentiation|Collagen Type I|Cells, Cultured|Gene Expression Regulation 84 Prrx2 31471104 Pathol. Res. Pract. 2019 10.1016/j.prp.2019.152593 0 4 0 246 Humans|Mice|Animals|Glycogen Synthase Kinase 3|*Wnt Signaling Pathway|beta Catenin|*Catenins|Epithelial-Mesenchymal Transition|Cadherins|Cell Movement|Colon Cancer|Gene Expression Regulation, Neoplastic|Vimentin|Cell Proliferation|Cell Line, Tumor|Lymphatic Metastasis|Liver Neoplasms|shRNA|Downregulation|PRRX2 protein, human|Homeodomain Proteins 84 Prrx2 31255287 Biochem. Biophys. Res. Commun. 2019 PMC6646072 10.1016/j.bbrc.2019.06.089 3 0 0 246 Humans|PRRX1 protein, human|Homeodomain Proteins|*Fibroblasts|*Neurons|Cell Transdifferentiation|Basic Helix-Loop-Helix Transcription Factors|Cellular Reprogramming|LIM-Homeodomain Proteins|TWIST1 protein, human|Twist-Related Protein 1|Nuclear Proteins|Transcription Factors|POU Domain Factors|Repressor Proteins|Regulatory Network, Gene|Embryo, Mammalian|Gene Expression Profiling|HEY2 protein, human 84 Prrx2 31197039 J. Biol. Chem. 2019 PMC6699834 10.1074/jbc.RA119.009001 3 0 0 246 *Phosphorylation|*Bicarbonates|*Epidermal Growth Factor|PTPN1 protein, human|*Protein Tyrosine Phosphatase 1B|*Oxidation-Reduction|Cell Signaling|Protein Tyrosine Kinase|Hydrogen Peroxide 84 Prrx2 30862546 Free Radic. Biol. Med. 2019 10.1016/j.freeradbiomed.2019.03.007 1 7 0 246 Humans|*Peroxiredoxin|*Neutrophils|Staphylococcus aureus|*Redox|Oxidants|Oxidative Burst|NADPH Oxidase|Peroxides|HL-60 Cells|Hydrogen Peroxide|Phorbol Myristate Acetate|Antioxidants|Cell Differentiation|Signal Transduction|diphenyleneiodonium|Onium Compounds|PRRX1 protein, human|Homeodomain Proteins 84 Prrx2 30844732 Front Biosci (Landmark Ed) 2019 1 1 0 246 Humans|*Hemoglobin Subunits|*Peroxiredoxin II|alpha(A) globin|Hemoglobins|Red Blood Cells|beta Globin|Chromatography, High Pressure Liquid|Peptide Fragments 84 Prrx2 30784599 Cell Rep 2019 10.1016/j.celrep.2019.01.081 3 2 0 246 *Peroxiredoxin|*Cell Death|Receptor-Interacting Protein Serine-Threonine Kinases|Inhibitor of Apoptosis Proteins|Baculoviral IAP Repeat-Containing 3 Protein|Receptors, Tumor Necrosis Factor, Type I|NF-kappa B|Apoptosis|Tumor Necrosis Factor-alpha|*Cytosol|Signal Transduction 84 Prrx2 30639614 Free Radic. Biol. Med. 2019 PMC6588440 10.1016/j.freeradbiomed.2019.01.005 1 9 0 246 Humans|*Chondrocytes|*Peroxiredoxin|*Mitogen-Activated Protein Kinases|*Signal Transduction|Proto-Oncogene Proteins c-akt|Oxidation-Reduction|Oxidative Stress|Vitamin K 3|Hydrogen Peroxide|*Joints 84 Prrx2 30611866 Free Radic. Biol. Med. 2019 10.1016/j.freeradbiomed.2019.01.001 2 4 0 246 Carcinoma, Hepatocellular|*Reactive Oxygen Species|Liver Neoplasms|*Peroxiredoxin|*Cancer Stem Cells|Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|Biomarkers, Tumor|Tumor Microenvironment|Downregulation|*Homeostasis 84 Prrx2 30605715 Free Radic. Biol. Med. 2019 10.1016/j.freeradbiomed.2018.12.032 1 2 0 246 Animals|*Peroxiredoxin II|*Oxidative Stress|*Ionizing Radiation|Redox|Radiation-Protective Agents|Apoptosis|Hydroperoxide|DNA Damage|Signal Transduction|Leukopenia|Xray|Homeodomain Proteins|Whole-Body Irradiation|Dose-Response Relationship, Radiation 84 PRSS56 31687280 PeerJ 2019 PMC6825751 10.7717/peerj.7968 0 0 0 17 *Cholangiocarcinoma|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Computational Biology|Gene Expression Regulation, Neoplastic|Prognosis|*Chromosome Mapping|*Correlation of Data|Bile Duct Neoplasms|Bile Ducts, Intrahepatic 26 PRSS56 31266062 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.18-26275 3 0 0 17 Humans|*Microphthalmos|Hyperopia, High|Hyperopia|Eye Diseases, Hereditary|*Sequencing, Whole Genome|*Chinese|Mutations|Pedigree|Membrane Proteins|Transcription Factors|Glaucoma, Angle-Closure 26 prune2 31390356 PLoS ONE 2019 PMC6685631 10.1371/journal.pone.0220441 1 0 0 110 Swine|Animals|*Brassica napus|*Transcriptome|Norway|*Meat|*Brassica rapa|Animal Feed|Diet|Body Composition|*Muscle, Skeletal|*Meal|Soy Bean|Genes, Regulator 34 prune2 31170959 BMC Cancer 2019 PMC6555734 10.1186/s12885-019-5772-4 0 13 0 110 Humans|*Apoptosis|*DNA Damage|Neuroblastoma|Ataxia Telangiectasia Mutated Proteins|E2F1 Transcription Factor|Cell Line, Tumor|Signal Transduction 34 PSRC1 31838625 Mol. Cell. Biochem. 2019 10.1007/s11010-019-03673-x 0 0 0 141 *Apo E|*Serine|Gene Expression Profiling|Gene Ontology|Gene Regulatory Networks|RNA, Long Noncoding|Transcriptome|*Transcription Factors|Atherosclerosis|RNA, Messenger|Computational Biology|*Livers 90 PSRC1 31722512 Mol. Cells 2019 PMC6939656 10.14348/molcells.2019.0142 0 10 0 141 Humans|*E3 Ligase|*Centrioles|*Mitosis|Mitotic Spindle|*Cell Cycle|Centrosome|Anaphase-Promoting Complex-Cyclosome|Microtubules|Kinesin|Ubiquitination|F-Box Proteins|HeLa Cells|Phosphoproteins|KIF2A protein, human 90 PSRC1 31679213 Crit Rev Oncog 2019 10.1615/CritRevOncog.2019031335 0 0 0 141 *Computational Biology|Early Detection of Cancer|*Pancreatic Cancer|miRNA|Sequencing, Next-Generation|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|RNA, Messenger 90 PSRC1 31456134 Funct. Integr. Genomics 2019 10.1007/s10142-019-00706-y 0 0 0 141 Humans|Female|*Uterine Cervical Neoplasms|*Transcriptome|E6 protein, Human papillomavirus type 16|Oncogene Proteins, Viral|oncogene protein E7, Human papillomavirus type 16|Papillomavirus E7 Proteins|HPV 16|Repressor Proteins|Papillomavirus Infections|Gene Annotation|Gene Ontology|Gene Expression Profiling|Genes, cdc|NDC80 protein, human|Nuclear Proteins|Gene Expression Regulation, Neoplastic|Oncogenes|Cell Line, Tumor 90 PSRC1 31393916 PLoS ONE 2019 PMC6687110 10.1371/journal.pone.0220827 2 0 0 141 Humans|*Hispanic|Genome-Wide Association Study|European Continental Ancestry Group|African Americans|*Lipids|Gene Frequency|*Phenotypes|Ethnicity|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Cholesterol, HDL|*Gene Expression Regulation|Cholesterol, LDL|Genotype|Triglycerides|Cohort Studies 90 PSRC1 31249592 Front Genet 2019 PMC6584752 10.3389/fgene.2019.00540 0 5 0 141 Humans|Pregnancy|Female|Infant, Newborn|*Lipid Metabolism|*Circadian Clocks|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Triglycerides|Cholesterol, LDL|Lipids|Preterm Birth 90 PSRC1 30902787 Gene 2019 10.1016/j.gene.2019.02.101 0 0 0 141 *Coronary Artery Disease|*Lipid Metabolism|Genome-Wide Association Study|Cholesterol Ester Transfer Proteins|SNPs|Cholesterol, HDL|Genetic Predisposition to Disease|Gene Frequency|Triglycerides|Case-Control Studies|Risk Factors 90 PSRC1 30864331 Pac Symp Biocomput 2019 PMC6417797 1 0 0 141 Humans|Genome-Wide Association Study|*Transcriptome|Quantitative Trait Loci|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|Gene Expression Profiling|Genotype|Gene Expression Regulation 90 PSRC1 30740535 Wellcome Open Res 2019 PMC6348437 10.12688/wellcomeopenres.14788.2 3 1 0 141 90 PTAFR 31638091 Neural Regen Res 2019 PMC6975135 10.4103/1673-5374.266924 1 0 0 671 Humans|*Transcriptome|*Head Trauma|Brain Concussion|Traumatic Brain Injury|*Extracellular Vesicles|*Inflammation|Biomarkers|Neuropsychological Tests|Emergency Department|LTB4R2 protein, human|Receptors, Leukotriene B4 39 PTAFR 31080696 J Alzheimers Dis Parkinsonism 2019 PMC6505709 10.4172/2161-0460.1000460 1 1 0 671 *Alzheimer Disease|*Algorithm|DNA Microarray|Gene Expression Profiling 39 PTAFR 30866528 Nutrients 2019 PMC6471786 10.3390/nu11030574 1 3 0 671 Male|Pdgfra-Associated Chronic Eosinophilic Leukemia|Eosinophilic Leukemia|*Cell Cycle Arrest|*Cell Differentiation|Cell Proliferation|mRNA Cleavage and Polyadenylation Factors|Receptor, Platelet-Derived Growth Factor alpha|*Docosahexaenoic Acids|Oncogene Proteins, Fusion|Cell Line, Tumor|Cell Cycle|Eosinophils|Leukemia 39 PTBP2 31729427 Sci Rep 2019 PMC6858377 10.1038/s41598-019-53097-2 2 8 0 322 Animals|Polypyrimidine Tract-Binding Protein|Heterogeneous-Nuclear Ribonucleoproteins|*mRNA Stability|*Tumorigenesis|*Cell Transformation, Neoplastic|Downregulation|Alternative Splicing|Gene Expression Regulation, Neoplastic|mRNA|Cell Movement|Cell Proliferation|Up-Regulation|Apoptosis|Signal Transduction|Cell Line, Tumor|Exons 77 PTBP2 31479777 Theriogenology 2019 10.1016/j.theriogenology.2019.08.031 2 0 0 322 Swine|Animals|Male|Female|Humans|*Genome-Wide Association Study|*Teratozoospermia|Semen|Semen Analysis|Sperm Motility|Artificial Insemination|Spermatozoa|Sus scrofa|Fertility|Phenotype|Spermatogenesis|Genes, Regulator|PELP1 protein, human|Transcription Factors|Co-Repressor Proteins|DICER1 protein, human|Ribonuclease III|DEAD-box RNA Helicases 77 PTBP2 31097689 Cell Death Dis 2019 PMC6522477 10.1038/s41419-019-1598-x 11 3 0 322 Humans|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|Neoplasm Recurrence, Local|lncRNA|*Proto-Oncogenes|*Genes, Neoplasm|Colorectal Neoplasms|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Colonic Neoplasms|mRNA 77 PTBP2 30944420 Int J Obes (Lond) 2019 PMC6776704 10.1038/s41366-019-0350-z 1 0 0 322 *Obesity, Abdominal|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Obesity|Body Mass Index|Genotype|Phenotype 77 PTBP2 30733148 Neuron 2019 PMC6474845 10.1016/j.neuron.2019.01.022 5 0 0 322 *Alternative Splicing|*RNA Splicing|*Neurons|Polypyrimidine Tract-Binding Protein|*Neurogenesis|Nerve Tissue Proteins|RNA Binding Protein|Exons|Neural Stem Cells|Brain|RNA, Messenger|Isoforms|Cells, Cultured 77 PTBP2 30726713 Int. J. Biochem. Cell Biol. 2019 10.1016/j.biocel.2019.01.018 0 4 0 322 Humans|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|Imatinib|Blast Crisis|K562 Cells|*Exon|Cell Proliferation|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Gene Expression Regulation, Leukemic|*Disease Progression|G2 Cell Cycle Arrest|Cell Line, Tumor|Apoptosis|MSI2 protein, human|RNA-Binding Proteins 77 PTBP2 30638744 Neuron 2019 PMC6649687 10.1016/j.neuron.2018.12.019 5 0 0 322 Animals|Mice|NOVA2 protein, human|*RNA-Binding Proteins|*Nerve Tissue Proteins|*RNA Splicing|*Neurons|*Neurogenesis|Polypyrimidine Tract-Binding Protein|Alternative Splicing|Mice, Knockout|RNA|Cells, Cultured|Ptbp2 protein, mouse|Nova2 protein, mouse|Antigens, Neoplasm 77 PTOV1 31552087 Front Genet 2019 PMC6737999 10.3389/fgene.2019.00766 2 0 0 127 Humans|Female|*Endometriosis|Quality of Life|*Transcriptome|*Machine Learning|Machine, Support Vector|Sequence Analysis, RNA|Supervised Machine Learning|Gene Expression Profiling|Discriminant Analysis|*Computational Biology|Least Squares|Model, Linear 38 PTOV1 31387622 J. Exp. Clin. Cancer Res. 2019 PMC6685258 10.1186/s13046-019-1349-y 1 5 0 127 Humans|Male|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Cancer Stem Cell|Cell Proliferation|Prognosis|Apoptosis|Cell Movement|Cell Line, Tumor|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Oncogene|PTOV1 protein, human|Neoplasm Proteins 38 PTOV1 31083670 PLoS ONE 2019 PMC6513092 10.1371/journal.pone.0211658 1 0 0 127 NIMA-Interacting Peptidylprolyl Isomerase|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Peptidylprolyl Isomerase|Gene Knockdown Techniques 38 PTOV1 31050705 Carcinogenesis 2019 10.1093/carcin/bgz080 1 0 0 127 Humans|Male|*Laryngeal Neoplasms|*Autophagy|Sequestosome-1 Protein|Autophagy-Related Protein 5|Microtubule-Associated Proteins|Autophagy-Related Proteins|Immunohistochemistry|Prostatic Neoplasms|PTOV1 protein, human|Neoplasm Proteins|Biomarkers, Tumor 38 PTOV1 30922918 Cancer Lett. 2019 10.1016/j.canlet.2019.03.019 0 4 0 127 Humans|Male|Neoplasm Recurrence, Local|*Prostate Cancer|Neoplasm Proteins|Biomarkers, Tumor|Prostate|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Immunohistochemistry|Disease Progression|DNA|PTOV1 protein, human|CCNG2 protein, human|Cyclin G2|ALDH1A1 protein, human|Aldehyde Dehydrogenase 38 PTOV1 30655072 Comput Biol Chem 2019 10.1016/j.compbiolchem.2018.12.022 1 0 0 127 Cluster Analysis|Algorithm|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Network, Gene|*Gene Expression|*Biochemical Phenomena|Saccharomyces cerevisiae 38 PTP4A3 31748560 Sci Rep 2019 PMC6868129 10.1038/s41598-019-52841-y 0 0 0 1135 Humans|Uveal melanoma|*Prospective Studies|Neoplasm Recurrence, Local|*Uveal Neoplasms|*Melanoma|*Liver Neoplasms|Prognosis|*Gene Expression|Gene Expression Regulation, Neoplastic|*Neoplasms, Glandular and Epithelial|Gene Expression Profiling|Real Time PCR|PTP4A3 protein, human|Neoplasm Proteins|Protein Tyrosine Phosphatases 266 PTP4A3 31601683 J. Pharmacol. Exp. Ther. 2019 PMC6856870 10.1124/jpet.119.262188 1 0 0 1135 Humans|Protein Tyrosine Phosphatases|*Oncogenes|*Oncogenesis|Neoplasm Proteins|Cell Line, Tumor|*B-Lymphocytes|*Protein Tyrosine Phosphatases, Non-Receptor|PTP4A3 protein, human 266 PTP4A3 31337650 Cancer Res. 2019 10.1158/0008-5472.CAN-19-0343 4 12 0 1135 Humans|*Multiple Myeloma|*Interleukin-6|STAT3 protein, human|*STAT3 Transcription Factor|Bortezomib|Apoptosis|Boronic Acids|Thalidomide|Pyrazines|Cell Proliferation|Signal Transduction|Cell Line, Tumor|Drug Resistance, Neoplasm|Phosphorylation|Gene Expression Regulation, Neoplastic|Cell Survival|Xenograft Model Antitumor Assays 266 PTP4A3 31307888 Bioorg. Med. Chem. Lett. 2019 10.1016/j.bmcl.2019.06.048 1 0 0 1135 PTP4A1 protein, human|*Protein Tyrosine Phosphatase|Enzyme Inhibitors|Phosphorylation|Structure-Activity Relationships|Sites, Active|Drug Discovery|Models, Molecular|Tyrosine|Membrane Proteins|Cell Cycle Proteins 266 PTP4A3 31298325 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201907_18311 0 2 0 1135 Humans|*Colorectal Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|*Tumorigenesis|Prognosis|Cell Proliferation|Cell Movement|Cell Line, Tumor|*Colonic Neoplasms|PTP4A3 protein, human|Neoplasm Proteins|Protein Tyrosine Phosphatases 266 PTP4A3 31207239 J. Mol. Biol. 2019 10.1016/j.jmb.2019.06.008 1 0 0 1135 PTP4A3 protein, human|Protein Tyrosine Phosphatases|Neoplasm Proteins|Cell Movement|Signal Transduction|rhoA GTP-Binding Protein|Cell Line, Tumor|Cytoskeleton|*Protein Tyrosine Phosphatases, Non-Receptor 266 PTP4A3 31171773 Nat Commun 2019 PMC6554295 10.1038/s41467-019-10127-x 2 1 0 1135 *Immunotherapy|*Antibodies, Monoclonal|Antibody-Dependent Cell Cytotoxicity|*Immunologic Factors|Antineoplastic Agents, Immunological|*Oncogene Proteins|Receptors, IgG|Cell Line, Tumor|Neoplasm Proteins|Xenograft Model Antitumor Assays|Killer Cells, Natural 266 PTP4A3 30888986 Chin. Med. J. 2019 PMC6629362 10.1097/CM9.0000000000000203 0 0 0 1135 Humans|Female|*Endometrial Cancer|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|MicroRNAs|RNA, Messenger|Tumorigenesis|Cell Line, Tumor|Cell Transformation, Neoplastic|Prognosis 266 PTP4A3 30864736 Oncol. Rep. 2019 PMC6448091 10.3892/or.2019.7049 1 7 0 1135 Mice|Animals|Mice, Nude|*Colorectal Cancer|*Mitogen-Activated Protein Kinases|*Colonic Neoplasms|*Neovascularization, Pathologic|*Macrophages|Neoplasm Invasiveness|Signal Transduction|Epithelial-Mesenchymal Transition|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Interleukin 6 266 PTP4A3 30816227 Sci Rep 2019 PMC6395723 10.1038/s41598-019-39643-y 1 31 0 1135 Humans|Uveal melanoma|PTP4A3 protein, human|*Uveal Neoplasms|Protein Tyrosine Phosphatases|*Melanoma|Neoplasm Proteins|Cell Movement|Cell Line, Tumor|*Protein Tyrosine Phosphatases, Non-Receptor 266 PTP4A3 30746541 Org. Biomol. Chem. 2019 10.1039/c9ob00025a 1 0 0 1135 *Enzyme Inhibitors|Protein Tyrosine Phosphatase|pyridine|Pyridines|Structure-Activity Relationship|Pyridones|*Protein Tyrosine Phosphatases, Non-Receptor|Neoplasm Proteins|Cancer|Imines 266 PTPRCAP 31661482 Mol. Biol. (Mosk.) 2019 10.1134/S0026898419050112 0 2 0 34 Humans|*Lymphocyte Activation|PTPRC protein, human|Leukocyte Common Antigens|Membrane Proteins|*Phosphatase, Phosphoprotein|Intracellular Signaling Peptides and Proteins|Phosphoproteins|Phosphorylation|CD71 antigen|Receptors, Transferrin|Antigens, CD|Jurkat Cells|Protein Binding|Cell Signaling|Co-Immunoprecipitation|SLC1A4 protein, human|Amino Acid Transport System ASC 48 PTPRCAP 31537385 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.09.041 0 4 0 34 *Phosphorylation|PTPRC protein, human|Leukocyte Common Antigens|*Phosphatase, Phosphoprotein|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Lymphocyte Activation|Phosphoproteins|*Lymphocyte|MAPK3 protein, human|Kinase, ERK1|Protein Binding|Signal Transduction|Receptors, Antigen, T-Cell 48 PTPRE 31844669 Sci Adv 2019 PMC6905863 10.1126/sciadv.aax9230 2 0 0 152 *RNA, Long Noncoding|Macrophage Activation|Cell Proliferation|Macrophages|Cell Line, Tumor 70 PTPRE 31722979 J. Cell. Sci. 2019 10.1242/jcs.234641 0 1 0 152 *Podosomes|*Signal Transduction|*Macrophage Activation|Receptor-Like Protein Tyrosine Phosphatases, Class 4|*Macrophages|Protein Tyrosine Phosphatase|Phosphorylation|Amino Acid Sequence|cysteinyl-leukotriene|Leukotrienes|*Cell Movement|Cysteine 70 PTPRE 31655274 J Biomed Inform 2019 10.1016/j.jbi.2019.103313 3 0 0 152 Humans|Female|*Computational Biology|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Prognosis|Gene Expression Profiling|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Cancer Biomarkers|CDH1 protein, human|Cadherins|Kaplan-Meier Estimate|*Disease Progression|Ovary|*Machine Learning|Transcriptome|Antigens, CD|BSCL2 protein, human|GTP-Binding Protein gamma Subunits 70 PTPRE 30993080 J Biol Res (Thessalon) 2019 PMC6449998 10.1186/s40709-019-0094-x 5 0 0 152 Humans|Male|Female|*Alopecia|Hair Follicle|beta Catenin|Cell Differentiation|*Biomarkers|Signal Transduction 70 PTPRE 30662530 J Cancer 2019 PMC6329871 10.7150/jca.27633 1 0 0 152 PTPRE protein, human|*Receptor-Like Protein Tyrosine Phosphatases, Class 4|*Phosphorylation|Receptors, IgE|Tyrosine Kinase|Signal Transduction|Mast Cells|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Osteoclast|Proteins 70 PTPRM 31494761 Med. Oncol. 2019 10.1007/s12032-019-1311-z 3 0 0 98 *Carcinoma, Hepatocellular|*Liver Neoplasms|*RNA, Circular|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Downregulation|Hep G2 Cells|Tumorigenesis|Cell Movement|Upregulation|Cell Line, Tumor|Apoptosis|Disease Progression|siRNA 52 PTPRM 31349215 Endocr Connect 2019 PMC6687034 10.1530/EC-19-0279 0 5 0 98 *Intestinal Neoplasms|*Neuroendocrine Tumors|Intestine, Small|Genes, Tumor Suppressor|Methylation|DNA Copy Number Variations 52 PTPRM 30997484 J. Anim. Sci. 2019 PMC6606496 10.1093/jas/skz121 1 0 0 98 Female|Cattle|Animals|Genome-Wide Association Study|Sexual Maturation|*Breeding|*Phenotype|*Genomics|Reproduction|Linkage Disequilibrium|Genotype|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Chromosome 52 PTPRM 30685201 Cytokine 2019 10.1016/j.cyto.2018.12.014 3 1 0 98 Humans|*Lupus Erythematosus, Systemic|interferon-alpha 8|Interferon-alpha|*Antiviral Agents|*Phenotype|Genetic Predisposition to Disease|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Haplotypes|African Americans|Interferon Regulatory Factors|Case-Control Studies|Autoantibodies 52 PURG 31405924 J. Neurosci. 2019 PMC6764200 10.1523/JNEUROSCI.0401-19.2019 0 0 0 44 Male|Humans|Female|*Noradrenaline|*Dopamine|Double-Blind Method|Propranolol|Adrenergic beta-Antagonists|Amisulpride|Dopamine Antagonists|Episodic Memory|Arousal|Neuromodulators 36 PYHIN1 31843671 Int. J. Infect. Dis. 2019 PMC7197195 10.1016/j.ijid.2019.12.013 1 0 0 57 *Interferon|Brazil|*Tuberculosis|Mycobacterium tuberculosis|Tuberculin Test|Tuberculosis, Pulmonary|Contact Tracing|*Antiviral Agents|*Genetic Polymorphisms 20 PYHIN1 31118907 Front Psychiatry 2019 PMC6504680 10.3389/fpsyt.2019.00280 0 1 0 57 Humans|*Transcriptome|*Bipolar Disorder|Gene Expression Profiling|RNA, Long Noncoding|Sequencing, RNA|mRNA 20 PYHIN1 30867653 Cancer Cell Int. 2019 PMC6399908 10.1186/s12935-019-0753-x 2 6 0 57 Humans|Male|*Transcriptome|*DNA Methylation|Bioinformatics|*Prostate Cancer|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Databases, Genetic|Protein Interaction Maps|Biomarkers, Tumor 20 PYY3 31805040 PLoS Biol. 2019 PMC6894749 10.1371/journal.pbio.3000482 0 0 0 0 Animals|*Appetite Depressants|peptide YY (3-36)|Peptide YY|*Feeding Behavior|Glucagon-Like Peptide 1|Eating|Peptide Fragments|Obesity|Leptin 181 PYY3 31771994 J. Pharmacol. Exp. Ther. 2019 10.1124/jpet.119.262584 0 3 0 0 Mice|Animals|*Neuropeptide Y|Pruritus|Receptors, Neuropeptide Y|Ganglia, Spinal|Peptide YY|Mice, Inbred C57BL|Peptide Fragments 181 PYY3 31628465 J. Clin. Endocrinol. Metab. 2019 PMC7093052 10.1210/clinem/dgz103 0 0 0 0 Humans|Male|Animals|*Peptide YY|Luteinizing Hormone|Follicle Stimulating Hormone|Gonadotropin-Releasing Hormone|Kisspeptins|Testosterone|*Health, Men's 181 PYY3 31548004 Surg Obes Relat Dis 2019 10.1016/j.soard.2019.04.008 1 0 0 0 Humans|*GLP 1|Obesity, Morbid|Roux-en-Y Gastric Bypass|Weight Loss|Glucagon-Like Peptide-1 Receptor|Eating|Feeding Behavior|Energy Metabolism|Peptide Fragments 181 PYY3 31517617 Endocr Regul 2019 10.2478/enr-2019-0004 0 4 0 0 Rats|Animals|*Streptozocin|Diabetes Mellitus, Type 2|peptide YY (3-36)|*Peptide YY|*Streptozotocin Diabetes|*Peptide Fragments|Receptors, Neuropeptide Y|tyrosyltyrosine|*Dipeptides|Diet, High-Fat|Blood Glucose|Eating|Insulin|Body Weight|Tyrosine 181 PYY3 31310716 Mol. Pharm. 2019 10.1021/acs.molpharmaceut.9b00554 1 1 0 0 *Peptide YY|*Half-Life|Anti-Obesity Agents|Receptors, Neuropeptide Y|*Climacteric|Obesity|*Menopause|Structure-Activity Relationship|Peptide Fragments 181 PYY3 31074796 Endocrinology 2019 PMC6806261 10.1210/en.2019-00100 2 4 0 0 Humans|Male|Mice|Animals|*Neuropeptide Y|peptide YY (3-36)|*Peptide YY|*Agouti-Related Protein|Arcuate Nucleus of Hypothalamus|*Neurons|Receptors, Neuropeptide Y|Ghrelin|Peptide Fragments|Eating|Hypothalamus|*Cuniculidae|Body Weight|Potential, Action|Satiety Response 181 PYY3 30994696 Org. Biomol. Chem. 2019 10.1039/c9ob00550a 0 2 0 0 eumelanin|*Melanins|*Tyrosine|*Monophenol Monooxygenase|peptide YY (3-36)|*Peptide Fragments|Peptide YY|*Oxidation-Reduction|Dihydroxyphenylalanine|Lipopeptides|Micelles|Peptide Hormones|Hydrogen-Ion Concentration|Hydrogels 181 PYY3 30773465 Cell Metab. 2019 PMC6701930 10.1016/j.cmet.2019.01.017 3 1 0 0 *Peptide YY|Weight Loss|Obesity|Eating|Glucagon-Like Peptide 1|Energy Intake|Energy Metabolism 181 PYY3 30724002 Diabetes Obes Metab 2019 10.1111/dom.13654 6 1 0 0 Humans|Diabetes Mellitus, Type 2|*Obesity|*Sodium-Glucose Transporter 2 Inhibitors|*Body Weight|Incretins|Hypoglycemic Agents|Gastric Inhibitory Polypeptide|Blood Glucose|Glucagon-Like Peptide 1|SLC5A1 protein, human|Sodium-Glucose Transporter 1|Insulin 181 PYY3 30609361 J Phys Chem B 2019 PMC7005981 10.1021/acs.jpcb.8b11097 1 0 0 0 *Lipopeptides|*Peptide Fragments|*Peptide, PYY|Micelles|Peptide Hormones|*Gastrointestinal Hormones|Hydrogen-Ion Concentration|Protein Binding 181 RAD54B 31711518 Parasit Vectors 2019 PMC6849265 10.1186/s13071-019-3792-1 0 1 0 120 Humans|Animals|*Drosophila melanogaster|*Aedes|DNA Repair|DNA Breaks, Double-Stranded|DNA End-Joining Repair|DNA Damage|Recombination, Genetic 67 RAD54B 31612045 Oncol Lett 2019 PMC6781656 10.3892/ol.2019.10854 0 0 0 120 Humans|Female|RAD54B protein, human|*DNA Helicases|*Nuclear Proteins|DNA-Binding Proteins|Biomarkers, Tumor 67 RAD54B 31545289 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109341 0 1 0 120 Humans|RAD54L protein, human|*DNA Helicases|RAD54B protein, human|*Nuclear Proteins|Cell Proliferation|Gene Expression Regulation, Neoplastic|Prognosis|MCF-7 Cell|Apoptosis|Biomarkers, Tumor|Cell Line, Tumor|Kaplan-Meier Estimate|Cell Cycle 67 RAD54B 30710290 Methods Mol. Biol. 2019 10.1007/978-1-4939-9030-6_28 0 1 0 120 *DNA Repair|DNA Damage|DNA Breaks, Double-Stranded|Rad51 Recombinase|Recombinational DNA Repair 67 RAP1GDS1 31406347 Nat. Genet. 2019 PMC7159804 10.1038/s41588-019-0475-y 2 2 0 152 *Proto-Oncogene Proteins p21(ras)|Pancreatic Carcinoma|*Pancreatic Neoplasms|Pancreatic carcinoma, familial|Carcinoma, Pancreatic Ductal|*Mutations|*Prenylation|Cell Proliferation 48 RAP1GDS1 31197034 J. Biol. Chem. 2019 PMC6682747 10.1074/jbc.RA119.007438 1 1 0 152 *Small GTPases|Guanine Nucleotide Exchange Factors|Guanosine Diphosphate|*Molecular Chaperones|Guanosine Triphosphate|Protein Prenylation|Amino Acid Sequence|Protein Binding|rhoA GTP-Binding Protein|ras GTPases|Signal Transduction|Plasma Membrane 48 rap2a 31193517 Data Brief 2019 PMC6531833 10.1016/j.dib.2019.103965 0 3 0 251 Mice|Animals|*Lipopolysaccharides|*GTPase|Macrophages|*Innate Immune Response|NF-kappa B|Monocytes|RAW 264.7 Cells|Nitric Oxide Synthase Type II|Inflammation|Signal Transduction|Tumor Necrosis Factor-alpha|Rap2a protein, mouse|rap GTP-Binding Proteins 128 rap2a 30851634 Mol. Immunol. 2019 10.1016/j.molimm.2019.02.015 0 12 0 251 Mice|Animals|*Macrophages|Toll-Like Receptors|NF-kappa B|Inflammation|Signal Transduction|Lipopolysaccharides|RAW 264.7 Cells|Cytokines|Transcription Factor RelA|Interleukin-6|Tumor Necrosis Factor-alpha|Phosphorylation|Immunity, Innate|*Gene Expression|Small GTPases|Rap2a protein, mouse|rap GTP-Binding Proteins 128 rap2a 30826466 Biochim Biophys Acta Mol Basis Dis 2019 10.1016/j.bbadis.2019.02.020 0 4 0 251 Animals|Pregnancy|Female|*Up-Regulation|*Depression|*Signal Transduction|Neurons|Poly I-C|Behavior, Animal|Prenatal Exposure Delayed Effects|Hippocampus|*Inflammation|*Transcriptional Activation|Dendrites 128 rap2a 30625033 Mol. Biol. Cell 2019 PMC6589701 10.1091/mbc.E18-08-0531 2 3 0 251 Humans|Mice|Animals|*Junctional Adhesion Molecule A|*Phosphorylation|F11R protein, human|*Cell Adhesion Molecules|*Receptors, Cell Surface|*Intestines|Tight Junction|Intestinal Mucosa|*Inflammation|Cells, Epithelial|Permeability|Colitis|Signal Transduction|Colitis, Ulcerative|afadin|Microfilament Proteins|Colon|Tyrosine 128 RAPGEF6 31647804 PLoS Genet. 2019 PMC6812752 10.1371/journal.pgen.1008416 1 0 0 96 Dogs|Animals|*Vocal Cord Paralysis|Genome-Wide Association Study|*Risk Factors|Cartilages, Arytenoid|Dog Diseases|Haplotype|Exon|Allele|Frameshift Mutation|RNA Splicing|Stop Codon, Premature|Sequencing, Whole Genome 25 RAPGEF6 31137587 Genes (Basel) 2019 PMC6562510 10.3390/genes10050384 0 0 0 96 Animals|Genome-Wide Association Study|Chickens|Eggs|Avian Proteins|Genotype|SNPs|Phenotype|Oviposition|Haplotypes|Quantitative Trait Loci 25 RASGEF1B 31887652 Theriogenology 2019 10.1016/j.theriogenology.2019.12.014 0 0 0 25 Female|Cattle|Animals|Vascular Endothelial Growth Factor A|*GTPase|*Corpus Luteum|Luteolysis|Estrous Cycle|Dinoprost|progesterone receptor B|Progesterone Receptor|estrogen receptor alpha, human|Estrogen Receptor alpha|mRNA|ANGPT1 protein, human|Angiopoietin-1|Ovaries|enhancer-binding protein AP-3|Transcription Factors|DNA-Binding Proteins|ras Guanine Nucleotide Exchange Factors 28 RASGEF1B 31044621 Blood Press. 2019 10.1080/08037051.2019.1604066 0 2 0 25 28 RASGEF1B 31001083 Front Mol Neurosci 2019 PMC6454190 10.3389/fnmol.2019.00075 1 0 0 25 Interneurons|Parvalbumins|Medial Eminence|Neurogenesis|Somatostatin|Cerebral Cortex|Cell Differentiation|Transcription Factors|Cell Movement|Nerve Tissue Proteins|3'-(1-butylphosphoryl)adenosine 28 RASGEF1B 30851634 Mol. Immunol. 2019 10.1016/j.molimm.2019.02.015 2 12 0 25 Mice|Animals|*Macrophages|Toll-Like Receptors|NF-kappa B|Inflammation|Signal Transduction|Lipopolysaccharides|RAW 264.7 Cells|Cytokines|Transcription Factor RelA|Interleukin-6|Tumor Necrosis Factor-alpha|Phosphorylation|Immunity, Innate|*Gene Expression|Small GTPases|Rap2a protein, mouse|rap GTP-Binding Proteins 28 RASGEF1B 30662451 Front Genet 2019 PMC6329279 10.3389/fgene.2018.00682 1 0 0 25 *Cancer|CD274 protein, human|B7-H1 Antigen|*Oncogenes|Immunotherapy|CTLA4 protein, human|CTLA-4 Antigen|Data Mining|Databases, Genetic|*Gene Expression 28 RAX2 30607024 Genet. Med. 2019 PMC6752296 10.1038/s41436-018-0392-y 0 0 0 14 Humans|*Retina|African Americans|Color|Text Messaging|Retinal Diseases 25 RBM20 31849696 Front Physiol 2019 PMC6892752 10.3389/fphys.2019.01436 2 0 0 136 TTN protein, human|*Connectin|*Cardiomyopathy|Cardiomyopathy, Dilated|*Cardiac Disease|*Post-Translational Modifications|Heart Failure|Myocytes, Cardiac|Mutation 88 RBM20 31768884 Curr Cardiol Rep 2019 PMC6877704 10.1007/s11886-019-1236-3 0 0 0 136 Humans|*Cardiomyopathy, Dilated|*Sudden Cardiac Death|Defibrillators, Implantable|*Cardiomyopathies|Primary Prevention|Electrocardiography|Risk Assessment|Risk Factors 88 RBM20 31717392 Int J Mol Sci 2019 PMC6888234 10.3390/ijms20225591 1 2 0 136 *Exon|Alternative Splicing|Calcium Channels, L-Type|Myocardium|Myocytes, Cardiac 88 RBM20 31614708 Int J Mol Sci 2019 PMC6829565 10.3390/ijms20205059 1 0 0 136 *Angiotensin II|*RNA Precursors|TTN protein, human|Titin|*RNA Splicing|Alternative Splicing|Myocytes, Cardiac|RNA-Binding Proteins|Sarcomeres|RNA-Binding Motif 88 RBM20 31583969 Acta Cardiol 2019 PMC7124986 10.1080/00015385.2019.1674490 1 0 0 136 88 RBM20 31419596 Forensic Sci. Int. 2019 10.1016/j.forsciint.2019.109906 1 0 0 136 Humans|Myotonic Dystrophy 1|*RNA Splicing|Myotonin-Protein Kinase|Exon|*Base Sequence|Trinucleotide Repeat Expansion|Alternative Splicing|*Sudden Cardiac Death|RNA-Binding Proteins|Muscle, Skeletal|*Sequencing, RNA|*Whole Exome Sequencing|LDB3 protein, human|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 88 RBM20 31314138 J. Physiol. (Lond.) 2019 PMC6852589 10.1113/JP277985 0 0 0 136 TTN protein, human|*Connectin|*Myocytes, Cardiac|*Diastole|Sarcomeres|Myocardial Contraction|Muscle Proteins|*Calcium, Dietary 88 RBM20 31221019 Vet. Pathol. 2019 PMC7221460 10.1177/0300985819854224 0 0 0 136 Rats|Animals|*Esophageal Achalasia|Connectin|Cardiomyopathy, Dilated|RNA Splicing|Myocytes, Cardiac|RNA-Binding Proteins|Mutation 88 RBM20 31197173 Nat Commun 2019 PMC6565679 10.1038/s41467-019-10487-4 3 0 0 136 Humans|*Insulin|*DNA Methylation|*Glucose|Diabetes Mellitus, Type 2|*Insulin, Regular, Human|CpG Islands|Epigenesis, Genetic|Obesity|*Homeostasis|Genome-Wide Association Study|Gene Expression Profiling|Gene Expression 88 RBM20 31092860 Sci Rep 2019 PMC6520409 10.1038/s41598-019-43881-5 2 0 0 136 Humans|Female|Adult|Male|*Body Mass Index|Obesity|Overweight|Gene Modules|Gene Chip|*Gene Expression|Genome-Wide Association Study|Gene Expression Profiling|Genome, Human|SLC30A3 protein, human|Cation Transport Proteins 88 RBM20 30980206 Clin Res Cardiol 2019 10.1007/s00392-019-01465-3 2 0 0 136 Humans|Adult|Isolated Noncompaction of the Ventricular Myocardium|Phenotype|Heart Ventricles|Echocardiography|Mutation 88 RBM20 30948719 Nat Commun 2019 PMC6449405 10.1038/s41467-019-09483-5 7 2 0 136 Humans|*RNA Splicing|Alternative Splicing|Connectin|*Genome|Myocytes, Cardiac|RNA Precursors|RNA-Binding Proteins|Cardiomyopathy, Dilated|*Organogenesis|Pluripotent Stem Cells|Cell Differentiation 88 RBM20 30871351 Circ Heart Fail 2019 PMC6422044 10.1161/CIRCHEARTFAILURE.118.005371 9 0 0 136 Humans|*Arrythmia|*Cardiomyopathy|Sudden Cardiac Arrest|Cardiomyopathy, Dilated|Tachycardia, Ventricular|Arrhythmogenic Right Ventricular Dysplasia|Implantable Defibrillator|Genetic Predisposition to Disease|Phenotype|Cardiomyocyte|Mutation|Exons|Cohort Studies 88 RBM20 30871348 Circ Heart Fail 2019 10.1161/CIRCHEARTFAILURE.118.005700 5 0 0 136 Male|Humans|Female|United States|*Cardiomyopathy, Dilated|Connectin|Heterozygote|Arrhythmias, Cardiac|Pedigree|Phenotype|Genetic Predisposition to Disease|Genetic Testing|Mutation|Myocytes, Cardiac|RNA-Binding Proteins|Mutation, Missense|Heart Transplantation|Allele Frequency 88 RBM24 31814023 Hum. Mol. Genet. 2019 PMC7068108 10.1093/hmg/ddz278 1 3 0 140 Humans|Animals|Mice|*Anophthalmos|*Microphthalmos|SOX2 protein, human|*SOXB1 Transcription Factors|*RNA Binding Protein|*Organogenesis|Eye Abnormalities|Transcription Factors|*Vertebrate|Mutations|RBM24 protein, human|Lhx2 protein, mouse|LIM-Homeodomain Proteins 41 RBM24 30626666 J. Virol. 2019 PMC6401439 10.1128/JVI.02161-18 2 4 0 140 *Hepatitis B virus|pgRNA|Gene Products, pol|Capsids|Reverse Transcriptase|Reverse Transcription|RNA, Viral|Virus Replication|Nucleic Acid Conformation|Protein Binding|RNA-Binding Motifs 41 RBMS3 31813757 Eur Neuropsychopharmacol 2019 10.1016/j.euroneuro.2019.11.004 0 1 0 104 Animals|Rats|*Maternal Deprivation|*Transcriptome|Epigenesis, Genetic|*Antidepressants|Escitalopram|Nortriptyline|Depression|Hippocampus|Resistant Depression, Treatment|Synaptic Transmission|RTN1 protein, human|Nerve Tissue Proteins|Frontal Cortex|Disease Models, Animal|Swimming 41 RBMS3 31712637 Gene Ther. 2019 10.1038/s41434-019-0108-1 0 4 0 104 Humans|Mice|Male|Animals|*RNA, Long Noncoding|Mice, Nude|*Upregulation|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|*Disease Progression|Cell Movement|Cell Line, Tumor|Tumorigenesis|*Genes, Regulator|*Prostate Cancer|RBMS3 protein, human|Trans-Activators|RNA-Binding Proteins|VASH1 protein, human|Cell Cycle Proteins 41 RBMS3 31694854 G3 (Bethesda) 2019 PMC6945038 10.1534/g3.119.400775 0 0 0 104 Humans|*Epistasis, Genetic|Genome-Wide Association Study|*Sclerosis, Systemic|Pulmonary Fibrosis|Lung|Fibrosis|*Respiratory Physiological Phenomena|Network, Gene|SNPs|Frequencies, Allele|Cohort Studies 41 RBMS3 31687947 Georgian Med News 2019 0 3 0 104 Humans|*Exfoliation Syndrome|Genome-Wide Association Study|*Genetic Markers|Amino Acid Oxidoreductases|Alleles|Genetic Predisposition to Disease|Glaucoma, Open-Angle|Polymorphism, Single Nucleotide|Haplotypes|Case-Control Study|Eyes 41 RBMS3 31611379 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6825283 10.1073/pnas.1911429116 0 0 0 104 Humans|*Autistic Disorder|*Esophageal Achalasia|Autism Spectrum Disorder|Intellectual Disability|Forkhead Transcription Factors|Repressor Proteins|Language Disorders|Mutation 41 RBMS3 31022475 Bone 2019 10.1016/j.bone.2019.04.010 1 0 0 104 Humans|*Pharmacogenetics|Genome-Wide Association Study|Bisphosphonate-Associated Osteonecrosis of the Jaw|Bone Density Conservation Agents|Diphosphonates|Osteoporosis|SNPs|Risk Factors|Neoplasms 41 RBMS3 30887286 Cell Oncol (Dordr) 2019 10.1007/s13402-019-00438-y 3 3 0 104 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Oncogene|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Gene Regulatory Networks|Cell Line, Tumor|Gene Expression Profiling 41 RBMS3 30819235 J. Exp. Clin. Cancer Res. 2019 PMC6394024 10.1186/s13046-019-1111-5 2 33 0 104 TWIST1 protein, human|*Twist-Related Protein 1|*Nuclear Proteins|*RNA Binding Protein|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Epithelial-Mesenchymal Transition|*Neoplastic Processes|Cell Line, Tumor|Lung Neoplasms 41 RC3H1 31636267 Nat Commun 2019 PMC6803705 10.1038/s41467-019-12704-6 0 0 0 430 Mice|Humans|Animals|*Mutation, Nonsense|*Syndrome|Inducible T-Cell Co-Stimulator Protein|T-Lymphocytes, Helper-Inducer|*Homozygote|Lymphocyte Activation|Ubiquitin-Protein Ligases|mRNA Decay|Repressor Proteins|Cytokines|Lymphocytes|Mutation|Lymphohistiocytosis, Hemophagocytic 71 RC3H1 31451648 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6744924 10.1073/pnas.1909314116 2 1 0 430 Humans|*Cytomegalovirus|Cytomegalovirus Infections|*Antiviral Agents|Innate Immune Response|Host-Pathogen Interactions|Immune Evasion|IRF1 protein, human|*Interferon Regulatory Factor-1|Cytokines|Viral Proteins|Virus Replication|Signal Transduction|Downregulation|Gene Expression 71 RC3H1 31449478 Immunol Med 2019 10.1080/25785826.2019.1655192 0 0 0 430 ZFP36 protein, human|Tristetraprolin|*RNA-Binding Proteins|RNA Stability|mRNA|Ribonucleases|*Autoimmune Diseases|Gene Expression Regulation|Transcription Factors|Cytokines|Endoribonucleases|Ubiquitin-Protein Ligases|Inflammation 71 RC3H1 31013298 PLoS ONE 2019 PMC6478326 10.1371/journal.pone.0215765 0 0 0 430 Humans|Mice|Animals|PCI 32765|*T Cell Lymphoma|Peripheral T-Cell Lymphoma|*Pyrimidines|*Pyrazoles|T-Lymphocytes, Helper-Inducer|RHOA protein, human|rhoA GTP-Binding Protein|Lymph Node|Antigens, CD|*MRI, Diffusion Weighted 71 REG1A 31877923 Genes (Basel) 2019 PMC7017422 10.3390/genes11010014 1 0 0 2130 *DNA Methylation|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|CpG Islands|Cancer Biomarkers|Promoter Regions, Genetic|Epigenesis, Genetic|Prognosis|Cell Free DNA|Pancreas|Chronic Pancreatitis 307 REG1A 31541294 Eur Arch Otorhinolaryngol 2019 PMC6942584 10.1007/s00405-019-05645-9 0 0 0 2130 Humans|*Nasopharyngeal Carcinoma|Case-Control Studies|*Single Nucleotide Polymorphisms|*Chinese|Genetic Susceptibility|Nasopharyngeal Neoplasms|China|Genotype|Haplotypes|Carcinoma|Nucleotides|REG1A protein, human|Lithostathine 307 REG1A 31511432 Biosci. Rep. 2019 PMC6757184 10.1042/BSR20192466 0 0 0 2130 Humans|Child|*Hepatoblastoma|beta Catenin|Liver Neoplasms|*Catenins|Wnt Signaling Pathway|MTOR protein, human|Mammalian Target of Rapamycin|YAP1 (Yes-associated) protein, human|Phosphoproteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|EGFR protein, human|Epidermal Growth Factor Receptor|Mutation|Short Interfering RNA|Adaptor Proteins, Signal Transducing|REG1A protein, human 307 REG1A 31166710 Am. J. Physiol., Cell Physiol. 2019 10.1152/ajpcell.00013.2019 2 3 0 2130 Humans|Animals|*MicroRNAs|Islet Cells|Lithostathine|Cell Differentiation|Pancreatitis-Associated Proteins|Pancreas|Pancreas, Exocrine|Cells, Acinar|Diabetes Mellitus, Experimental|mRNA|REG1A protein, human|MIRN7 microRNA, human 307 REG1A 31139647 Biomed Res Int 2019 PMC6500681 10.1155/2019/6970890 0 0 0 2130 Female|Humans|Pregnancy|Lithostathine|Case-Control Studies|Severity of Illness Index 307 REG1A 30988165 Mol. Cancer Res. 2019 10.1158/1541-7786.MCR-18-1195 1 1 0 2130 Humans|Tumor Suppressor Protein p53|Cell Line, Tumor|Carcinogenesis|Colon Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|Mutation 307 REG1A 30973271 Cancer Biother. Radiopharm. 2019 10.1089/cbr.2018.2746 1 7 0 2130 307 REG1A 30791110 Hepatology 2019 PMC6618260 10.1002/hep.30571 2 4 0 2130 Humans|Carcinoma, Hepatocellular|Liver Neoplasms|B virus, Hepatitis|hepatitis B virus X protein|Trans-Activators|Hepatitis B|*Hepatitis Virus|Hepatocytes|Virus Replication|Gene Expression Regulation, Neoplastic|Genomic Stability|REG1A protein, human|*Lithostathine|Cell Proliferation|Carcinogenesis 307 REG1A 30672312 Biomark Med 2019 10.2217/bmm-2018-0194 0 0 0 2130 Humans|REG1A protein, human|*Lithostathine|*Sepsis|Calcitonin|Procalcitonin|C-Reactive Protein|Biomarkers|Intensive Care Unit|Prognosis|ROC Curve|Prospective Studies 307 REG1A 30670912 World J. Gastroenterol. 2019 PMC6337015 10.3748/wjg.v25.i2.233 6 0 0 2130 Humans|*Barrett Esophagus|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Biomarkers, Tumor|Gene Regulatory Networks|Databases, Genetic|Computational Biology|RNA, Messenger 307 REG1A 30600408 Biochem. Genet. 2019 10.1007/s10528-018-9900-7 0 1 0 2130 Rats|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Phosphatidylinositol 3-Kinases|*Acute Hepatic Failure|Liver|Liver Regeneration|Signal Transduction|Cell Proliferation|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Apoptosis|Transcriptome|Clustering 307 REG1B 31857725 Br. J. Cancer 2019 PMC7054390 10.1038/s41416-019-0694-0 0 0 0 24 Humans|Pancreatic Carcinoma|*Pancreatic Cancer|Adenocarcinoma|Early Detection of Cancer|Carcinoma, Pancreatic Ductal|CA-19-9 Antigen|Biomarkers, Tumor|ROC Curve|Case-Control Studies 36 REG1B 31538697 Proteomics 2019 10.1002/pmic.201800489 2 0 0 24 *Computational Biology|*Workflow|*Pancreatic Cancer|Proteomics|Proteome|Cancer Biomarkers|Chromatography, Liquid|Software|Tandem Mass Spectrometry|Peptides 36 REG1B 31442248 PLoS ONE 2019 PMC6707605 10.1371/journal.pone.0221095 0 0 0 24 Child|Humans|Child, Preschool|*Gastrointestinal Microbiome|Pakistan|*Intestine, Small|*Inflammation|Stunting|Feces|Biomarkers|Malabsorption Syndrome|Failure to Thrive|Linear Regression|Flagellin|Permeability 36 REG1B 31166710 Am. J. Physiol., Cell Physiol. 2019 10.1152/ajpcell.00013.2019 2 3 0 24 Humans|Animals|*MicroRNAs|Islet Cells|Lithostathine|Cell Differentiation|Pancreatitis-Associated Proteins|Pancreas|Pancreas, Exocrine|Cells, Acinar|Diabetes Mellitus, Experimental|mRNA|REG1A protein, human|MIRN7 microRNA, human 36 REG1B 30884206 Cancer Med 2019 PMC6536975 10.1002/cam4.2071 6 0 0 24 Humans|*Colon Cancer|Prognosis|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Bioinformatic|Protein Interaction Maps|Kaplan-Meier Estimate|Transcriptome|Neoplasm Staging|ROC Curve|Survival Analysis|Transcription Factors|PNMA5 protein, human|Antigens, Neoplasm 36 RELT 31651789 Transplantation 2019 10.1097/TP.0000000000003035 0 0 0 87 Humans|*Kidney Transplantation|*Reoperation|*End Stage Liver Disease|Liver Transplantation|*Renal Insufficiency|*Liver|Graft Survival|Hepatitis C|Retrospective Studies|Risk Factors|*Morbidity|Kidney Failure, Chronic|Time Factors 46 RELT 31575895 Sci Rep 2019 PMC6773779 10.1038/s41598-019-50277-y 1 1 0 87 Mice|Animals|*Ameloblasts|*Cleavers|RELT|*Amelogenesis|*ADAM10 Protein|Organs, Enamel|Matrix Metalloproteinase 20|ADAM17 protein, human|ADAM-17|Cadherins|ADAM8 protein, human|ADAM Proteins|Cell Movement|Tetraspanins|Membrane Proteins|*Cytokinesis|Cell Membrane|Adam10 protein, mouse 46 RELT 31243044 Cancer Res. 2019 10.1158/0008-5472.CAN-18-3089 1 0 0 87 Animals|*Lung Cancer|*Drug Delivery Systems|Doxorubicin|peptide B|Liposomes|Peptide Library|Peptides|Cell Line, Tumor|Tissue Distribution|Disease Models, Animal 46 RELT 31178974 Oxid Med Cell Longev 2019 PMC6501224 10.1155/2019/8465030 4 6 0 87 Animals|ginsenoside Rg1|*Hydrogen Peroxide|*Chickens|*Ginsenosides|*Lymphocytes|*Spleen|Oxidative Stress|Antioxidants|Apoptosis|Signal Transduction|Cells, Cultured 46 RELT 30817902 Eur. J. Pharmacol. 2019 10.1016/j.ejphar.2019.02.041 2 1 0 87 Humans|Mice|Animals|RNA, Micro|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|MCF-7 Cells|Cell Line, Tumor|Antineoplastic Agents|India|China|MIRN18A microRNA, human 46 Resp18 31294787 Endocrinology 2019 10.1210/en.2019-00397 0 0 0 423 Animals|Male|Rats|regulated endocrine secretory protein 18|*Dahl Salt-Sensitive Rats|*Nerve Tissue Proteins|*Endocrine System|Pituitary Gland|PTPRN protein, human|Islet Cell Antigen 512|Pancreas|Blood Pressure|Thyroid Gland|RNA, Messenger|Testis|Kidney 23 Resp18 30979722 J. Biol. Chem. 2019 PMC6544868 10.1074/jbc.RA119.007607 0 0 0 423 *Receptor-Like Protein Tyrosine Phosphatases, Class 8|regulated endocrine secretory protein 18|*Nerve Tissue Proteins|*Insulin Antagonists|Secretory Granules|Islets of Langerhans|Insulin|Membrane Proteins|Diabetes Mellitus, Type 1|Autoantigens|Protein Tyrosine Phosphatases|Amino Acid Sequence 23 RETNLB 31800974 Mol Nutr Food Res 2019 PMC7079026 10.1002/mnfr.201900976 3 13 0 201 Humans|*Goblet Cells|*Milk, Human|*Oligosaccharides|Mucus|Interleukin-13|Intestinal Mucosa|*Homeostasis 152 RETNLB 30977971 Mol Nutr Food Res 2019 PMC6618108 10.1002/mnfr.201801427 1 0 0 201 *Goblet Cells|*Cytokines|*Lactic Acid Bacteria|*Mucus|Mucin-2|Intestinal Mucosa|Mucins|Interleukin-13|*Fibroblasts 152 RETNLB 30799148 Pediatr Neonatol 2019 10.1016/j.pedneo.2019.01.006 0 0 0 201 Humans|Infant|Infant, Newborn|*Enterocolitis, Necrotizing|*Preterm Infants|RETN protein, human|*Resistin|*Pilot Projects|Infant, Premature, Diseases|*Early Diagnosis|*Thrombocytopenia|ROC Curve|Biomarkers|*Infant, Newborn, Diseases|Case-Control Studies|Sepsis|*Plasma|*Leukopenia 152 RHBDF1 31828433 Protoplasma 2019 10.1007/s00709-019-01462-3 0 0 0 79 Humans|Breast Cancer, Familial|*Breast Neoplasms|*Protein Transport|Golgi Apparatus|*Cell Movement|Endoplasmic Reticulum|rab GTPases|Cell Proliferation|Biological Transport|NEDD9 protein, human|Phosphoproteins|Adaptor Proteins, Signal Transducing 30 RHBDF1 31776347 Nat Commun 2019 PMC6881440 10.1038/s41467-019-13404-x 0 0 0 79 Mice|Animals|*Chromatin|*Promoter Regions, Genetic|Enhancer Elements, Genetic|CCCTC-Binding Factor|Activation, Transcriptional|Transcription, Genetic|alpha-Globins|Binding Sites|Chickens 30 RHBDF1 31661139 Oncol. Rep. 2019 PMC6908940 10.3892/or.2019.7389 1 15 0 79 Humans|Female|*Uterine Cervical Neoplasms|HeLa Cells|Glycogen Synthase Kinase 3|*Prognosis|Cell Proliferation|RHBDF2 protein, human|*Carrier Proteins|Cell Movement|Wnt Pathway|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|beta Catenin|Epithelial-Mesenchymal Transition|Apoptosis|Oncogenesis 30 RHBDF1 31369701 J. Leukoc. Biol. 2019 10.1002/JLB.3VMR0219-069R 0 0 0 79 Animals|ADAM17 protein, human|ADAM-17|RHBDF2 protein, human|Carrier Proteins|ADAM Proteins|Proteins, Membrane-Associated|Proteolysis|Serine Proteinases|Cell Membrane|Protein Transport|Ligands|Endoplasmic Reticulum 30 RHBDF1 31075223 Exp. Eye Res. 2019 10.1016/j.exer.2019.04.018 0 0 0 79 *Retina|Injection, Intravitreal|Eye Proteins|Serpins|Laser Coagulation|Nerve Growth Factors|Vascular Endothelial Growth Factor A|*Lasers 30 RIMS2 31805716 Animals (Basel) 2019 PMC6941016 10.3390/ani9121055 0 0 0 81 Humans|Animals|Cattle|Genome-Wide Association Study|*Genome|*Phenotype|*Genomics|Quantitative Trait, Heritable|Breeding|Genotype|Models, Genetic|Polymorphism, Single Nucleotide|Meat|*Chinese 35 RIMS2 31153890 Prog. Neuropsychopharmacol. Biol. Psychiatry 2019 10.1016/j.pnpbp.2019.109659 0 0 0 81 Humans|*Tardive Dyskinesia|*Whole Exome Sequencing|Antipsychotics|Schizophrenia|Allele Frequency|Dyskinesia, Drug-Induced|Genetic Predisposition to Disease|Haplotypes|Polymorphism, Single Nucleotide|Genotype|Genetic Testing|Phenotype|Case-Control Studies 35 RIMS2 30842487 Sci Rep 2019 PMC6403379 10.1038/s41598-019-39873-0 4 6 0 81 Humans|Adolescent|Young Adult|Adult|Middle Aged|Aged|*miRNA|mRNA|Sequencing, RNA|Base Sequence|*Respiratory System 35 RIMS2 30692208 Genes Dev. 2019 PMC6362814 10.1101/gad.319194.118 5 4 0 81 *Claudin-2|afadin|Neoplasm Recurrence, Local|PDLIM2 protein, human|*Microfilament Proteins|Liver Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Liver|Signal Transduction|LIM Domain Proteins 35 RIMS2 30619482 Front Genet 2019 PMC6305546 10.3389/fgene.2018.00665 0 0 0 81 Humans|*DNA Copy Number Variations|*Autism Spectrum Disorder|*Chinese|*Cohort Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Europe|North America 35 RNASEH1 31798789 World J Diabetes 2019 PMC6885725 10.4239/wjd.v10.i11.534 0 0 0 176 Humans|*Diabetes Mellitus, Type 1|*Indians, North American|Colombia|European Continental Ancestry Group|Genetics, Population|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Ethnic Groups|Hispanic Americans|*Minority Groups 47 RNASEH1 31258551 Front Genet 2019 PMC6588129 10.3389/fgene.2019.00576 2 0 0 176 Adult|Humans|External Ophthalmoplegia, Progressive|mtDNA|DNA Polymerase gamma|DNA Replication|Mutations|Phenotype|Mitochondria 47 RNASEH1 31178343 DNA Repair (Amst.) 2019 10.1016/j.dnarep.2019.06.001 0 0 0 176 Humans|ribonuclease HI|*Ribonuclease H|DNA, Mitochondrial|DNA Replication|RNA primers|RNA|Mitochondrial Diseases|Mitochondria|Mutations|*Biochemical Phenomena 47 RNASEH1 31138795 Nat Commun 2019 PMC6538666 10.1038/s41467-019-10179-z 11 4 0 176 Humans|*Telomeres|*R-Loop Structures|*Telomere Lengthening|RecQ Helicases|Telomerase|DNA Replication|HeLa Cells|DNA|FANCM protein, human|DNA Helicases 47 RNASEH1 31034558 Nucleic Acids Res. 2019 PMC6582325 10.1093/nar/gkz247 0 0 0 176 Humans|Mice|Animals|Phosphorothioate Oligonucleotides|Oligonucleotides, Anti-Sense|Ribonuclease H|Protein Binding|DNA|HeLa Cells|Cell Nucleolus|Cell Membrane|*Phosphonates 47 RNASEH1 30996261 Nat Protoc 2019 PMC6604627 10.1038/s41596-019-0154-6 3 0 0 176 Animals|*R-Loop Structures|*Chromatin Immunoprecipitation|RNA|Nucleic Acid Conformation|DNA|*Genome Mapping|Nucleic Acid Hybridization|Ribonuclease H|Genome Instability|RNA Polymerase II|Transcription, Genetic|Genome 47 RNF39 31687280 PeerJ 2019 PMC6825751 10.7717/peerj.7968 1 0 0 8 *Cholangiocarcinoma|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Computational Biology|Gene Expression Regulation, Neoplastic|Prognosis|*Chromosome Mapping|*Correlation of Data|Bile Duct Neoplasms|Bile Ducts, Intrahepatic 22 RNF39 31103287 Fertil. Steril. 2019 10.1016/j.fertnstert.2019.03.020 1 2 0 8 Humans|Male|*DNA Methylation|*B-DNA|*Infertility, Male|CpG Islands|Oligospermia|Azoospermia|Spermatozoa|Spermatogenesis|Fertility|Case-Control Studies 22 RNF39 30782033 Gynecol. Endocrinol. 2019 10.1080/09513590.2019.1576617 2 0 0 8 Humans|Female|*Polycystic Ovary Syndrome|Genome-Wide Association Study|DNA Methylation|CpG Islands|Epigenesis, Genetic|Case-Control Studies|Genetic Predisposition to Disease|*Phenotypes|Gene Expression Profiling 22 RP1L1 31833436 Ophthalmic Genet. 2019 10.1080/13816810.2019.1703014 0 0 0 12 47 RP1L1 31725168 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.19-27486 0 0 0 12 *Macular Degeneration|*Coherence Tomography, Optical|Fluorescein Angiography|*Retinal Dystrophies|Electroretinography|Visual Acuity|Eye Proteins|*Eye Abnormalities|Mutation 47 RP1L1 31269856 Ophthalmic Genet. 2019 10.1080/13816810.2019.1633548 0 0 0 12 47 RP1L1 31236346 Int J Ophthalmol 2019 PMC6580197 10.18240/ijo.2019.06.06 0 0 0 12 Humans|*Whole Exome Sequencing|*Retinitis Pigmentosa|*Chinese|Exome|Genes, Recessive|Pedigree|Homozygote|Mutations|Eye Proteins|Sequence Analysis, DNA 47 RP1L1 31213501 J. Med. Genet. 2019 10.1136/jmedgenet-2018-105691 0 0 0 12 Humans|Japan|*Retinitis Pigmentosa|Usher Syndromes|Genes, Recessive|DNA Mutational Analysis|Asian|Pedigree|Exons|Eye Proteins|Mutation|Extracellular Matrix Proteins 47 RP1L1 31193770 Am J Ophthalmol Case Rep 2019 PMC6543024 10.1016/j.ajoc.2019.100465 0 0 0 12 Fluorescein Angiography|Electroretinography|Macular Degeneration|Tomography, Optical Coherence|Eye Proteins|Fundus Oculi|Visual Acuity|Pedigree|Phenotype|Mutation 47 RP1L1 31093368 J Ophthalmol 2019 PMC6481010 10.1155/2019/1691064 1 0 0 12 *Tomography, Optical Coherence|*Deep Learning|*Retina|*Retinal Diseases|Diabetic Retinopathy|Macular Dystrophy|Neural Networks, Computer|Eye Abnormalities 47 RP1L1 31028767 Ophthalmology 2019 10.1016/j.ophtha.2019.04.032 0 0 0 12 Humans|*Macular Degeneration|*Asian|Electroretinography|Fluorescein Angiography|Retina|Eye Proteins|*Retinal Dystrophies|Tomography, Optical Coherence|Pedigree|Phenotype|Visual Acuity|Mutation|*Eye Abnormalities|Cohort Studies|Asia|East Asia 47 rrad 31857616 Sci Rep 2019 PMC6923381 10.1038/s41598-019-55767-7 0 0 0 621 Humans|*Peritoneal Neoplasms|*Colorectal Cancer|*Genes, ras|ras Proteins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Gastric Cancer|*Colonic Neoplasms|*Stomach|*Diabetes Mellitus|RRAD protein, human 121 rrad 31839825 J Cancer 2019 PMC6909954 10.7150/jca.37070 2 0 0 621 SLC2A1 protein, human|*Glucose Transporter Type 1|oncogene protein E7, Human papillomavirus type 16|*Papillomavirus E7 Proteins|E6 protein, Human papillomavirus type 16|*Oncogene Proteins, Viral|*Repressor Proteins|*Lung Cancers|*Transcriptional Activation|*Up-Regulation|Human papillomavirus 16|*Hypoxia-Inducible Factor 1|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Downregulation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Neovascularization, Pathologic 121 rrad 31830958 BMC Musculoskelet Disord 2019 PMC6909478 10.1186/s12891-019-2970-9 2 2 0 621 Humans|Rats|Animals|Diabetes Mellitus, Type 2|*Fractures, Ununited|Fracture Healing|Small G-Proteins|Microarray Analysis 121 rrad 31147441 J. Biol. Chem. 2019 PMC6635439 10.1074/jbc.RA119.008782 0 2 0 621 Mice|Animals|*GTPase|*Myocardium|Sarcoplasmic Reticulum|Myocardial Contraction|Sarcoplasmic Reticulum Calcium-Transporting ATPases|Myocytes, Cardiac|Calcium Channels, L-Type|Ventricular Remodeling|Calcium Signaling|Heart Failure|Mice, Knockout 121 rrad 31114854 Eur. Heart J. 2019 PMC6769825 10.1093/eurheartj/ehz308 2 0 0 621 *Brugada Syndrome|*Myocytes, Cardiac|NAV1.5 Voltage-Gated Sodium Channel|*Mutation|Induced Pluripotent Stem Cells|Arrhythmias, Cardiac|Phenotype|Genetic Predisposition to Disease|*Cytoskeleton|Cardiac Disorder 121 rrad 31005260 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.04.035 1 2 0 621 Male|Female|Mice|Animals|*Adiposity|Adipocytes|Adipogenesis|*Obesity|3T3-L1 Cells|Adipose Tissue|Long Non-Coding RNA|Cell Differentiation|Lipid Metabolism|RNA, Messenger|Gene Knockdown Techniques|Downregulation 121 rrad 30881024 Onco Targets Ther 2019 PMC6400130 10.2147/OTT.S197844 0 18 0 621 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Downregulation|*Genes, ras|Gene Expression Regulation, Neoplastic|Hep G2 Cells|ACTG1 protein, human|*Actins|Cell Proliferation|Cell Line, Tumor|Prognosis|Apoptosis|rasagiline|*Indans|*Diabetes Mellitus 121 rrad 30838093 Oncotarget 2019 PMC6383823 10.18632/oncotarget.26660 3 3 0 621 Tumor Suppressor Protein p53|Cisplatin|Mutations|Cell Line, Tumor|*B Cells|Mitochondria|Polymorphism, Single Nucleotide 121 rrad 30826452 Contemp Clin Trials 2019 PMC6436980 10.1016/j.cct.2019.02.007 0 0 0 621 *Alzheimer Disease|*Risk Reduction|*Exercise|Cognitive Function|Brain|Hypertension|Antihypertensive Agents|Atrophy|Magnetic Resonance Imaging|Risk Factors|Blood Pressure|Disease Progression 121 RTTN 31598948 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.10.015 0 0 0 72 Child|Humans|Chromosome 18 ring|*Ring Chromosomes|*Cytogenetic|*Chromosomes, Human, Pair 18|Karyotyping|Developmental Disabilities|In Situ Hybridization, Fluorescence|Phenotype|Syndactyly 21 RTTN 30927481 Hum. Mutat. 2019 10.1002/humu.23755 0 0 0 72 Humans|Adult|*Microcephaly|*Brachydactyly|*Dwarfism|*Exon|Pituitary dwarfism 1|Homozygote|Exome|Pedigree|Carrier Proteins|Phenotype|Cell Cycle Proteins|Brain|Mutation|Magnetic Resonance Imaging|Allele|rotatin protein, human 21 RTTN 30879067 Brain 2019 PMC6439326 10.1093/brain/awz045 4 1 0 72 Humans|HEK293 Cells|Induced Pluripotent Stem Cells|Microcephaly|*Phenotypes|Dwarfism|Nervous System Malformations|Polymicrogyria|Lissencephaly|Carrier Proteins|Cell Cycle Proteins|Mutations|Brain|Centrosome|Cilia|Pedigree|*Biological Variation, Population|Introns|rotatin protein, human 21 RUNX1T1 31856435 Zhonghua Xue Ye Xue Za Zhi 2019 10.3760/cma.j.issn.0253-2727.2019.11.001 0 0 0 841 403 S100A14 31882495 In Vivo 2019 PMC6984099 10.21873/invivo.11777 0 0 0 114 *Colorectal Cancer|Prognosis|Liver Neoplasms|Biomarkers, Tumor|Neoplasm Recurrence, Local|Neoplasm Staging|Neoplasm Invasiveness|Lymphatic Metastasis|Survival Rate|*Colonic Neoplasms|Calcium-Binding Proteins|Cell Movement|Follow-Up Studies 69 S100A14 31821092 Genet Test Mol Biomarkers 2019 10.1089/gtmb.2019.0122 0 10 0 114 69 S100A14 31818115 Ceska Gynekol 2019 1 2 0 114 Female|*Tumor Markers|*Serum|S100 Protein Family|TFF3 protein, human|Trefoil Factor-3|*Tumor 69 S100A14 31305429 Medicine (Baltimore) 2019 PMC6641819 10.1097/MD.0000000000016356 0 0 0 114 Humans|*Prognosis|*Cancer|Biomarkers, Tumor|S100A14 protein, human|Calcium-Binding Proteins 69 S100A14 31263990 Clin. Exp. Metastasis 2019 10.1007/s10585-019-09979-w 0 2 0 114 Humans|Mice|Animals|Cell Line, Tumor|Cell Movement|Neoplasm Invasiveness|Lung Neoplasms|*Neoplastic Processes|Neoplasm Transplantation|Tumor Cell, Embolic|Gene Knockdown|Lung|Cell Proliferation|Disease Models, Animal|S100A14 protein, human|Calcium-Binding Proteins 69 S100A14 31123345 Br. J. Cancer 2019 PMC6738112 10.1038/s41416-019-0483-9 4 6 0 114 *S100 Proteins|*Interleukin-6|STAT3 protein, human|*STAT3 Transcription Factor|Pancreatic Carcinoma|*Pancreatic Cancer|*Signal Transduction|Transitions, Epithelial-Mesenchymal|Carcinoma, Pancreatic Ductal|IL11 protein, human|*IL-11|Zinc Finger E-box-Binding Homeobox 1|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cadherins|*Pancreas 69 S100A14 31105881 Oncotarget 2019 PMC6508202 10.18632/oncotarget.26861 0 0 0 114 Humans|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|S100 Protein Family|Carcinoma, Squamous Cell|Cell Proliferation|S100A14 protein, human|Calcium-Binding Proteins 69 S100A14 30980596 Mol Oncol 2019 PMC6822253 10.1002/1878-0261.12493 1 3 0 114 Humans|Mice|Animals|KLK6 protein, human|*Kallikrein B'|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Endopeptidases|Cell Movement|Downregulation|S100 Proteins|Transfections|S100A14 protein, human|Calcium-Binding Proteins|S100A16 protein, human 69 S100A14 30866526 Cancers (Basel) 2019 PMC6468488 10.3390/cancers11030327 2 2 0 114 Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Cell Line, Tumor|Prognosis|Sequencing, RNA 69 S100A16 31818115 Ceska Gynekol 2019 1 2 0 181 Female|*Tumor Markers|*Serum|S100 Protein Family|TFF3 protein, human|Trefoil Factor-3|*Tumor 46 S100A16 31796150 Oncol. Res. 2019 10.3727/096504019X15753718797664 0 8 0 181 *Epithelial-Mesenchymal Transition|*Stomach Neoplasms|RNA Interference|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|3' Untranslated Regions|Cell Line, Tumor|*Stomach|Down-Regulation|RNA, Small Interfering 46 S100A16 31399502 Biosci. Rep. 2019 PMC6734118 10.1042/BSR20182042 1 1 0 181 Mice|Animals|*Adipogenesis|*Up-Regulation|*11-beta-Hydroxysteroid Dehydrogenase Type 1|Cell, 3T3-L1|Adipocytes|Obesity|Cell Differentiation|*Transcriptional Activation 46 S100A16 31118765 Cancer Manag Res 2019 PMC6498975 10.2147/CMAR.S196450 0 0 0 181 46 S100A16 31069793 J. Cell. Physiol. 2019 10.1002/jcp.28748 1 1 0 181 Mice|Animals|*Lipogenesis|*Mice, Inbred C57BL|*Hepatocytes|*Livers|Lipid Metabolism|Diet, High-Fat|Non-alcoholic Fatty Liver Disease|Triglycerides|AMP-Activated Protein Kinase|Sterol Regulatory Element Binding Protein 1|Signal Transduction|Lipid Droplets 46 S100A16 31008487 Sheng Li Xue Bao 2019 0 4 0 181 Humans|*Endoplasmic Reticulum Stress|*Hep G2 Cells|ERN1 protein, human|Endoribonucleases|X-Box Binding Protein 1|Protein-Serine-Threonine Kinases|SREBP 1c|Lipid Metabolism|Lipogenesis|Hepatocytes|Heat Shock Protein|Liver|Signal Transduction|*S100 Proteins|Hepatoma|Up-Regulation|Triglycerides|Lipid Droplets 46 S100A16 30980596 Mol Oncol 2019 PMC6822253 10.1002/1878-0261.12493 1 3 0 181 Humans|Mice|Animals|KLK6 protein, human|*Kallikrein B'|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Endopeptidases|Cell Movement|Downregulation|S100 Proteins|Transfections|S100A14 protein, human|Calcium-Binding Proteins|S100A16 protein, human 46 S100A16 30916375 Br. J. Haematol. 2019 10.1111/bjh.15878 0 1 0 181 Adult|Humans|Mice|Animals|*Philadelphia Chromosome|Phosphatidylinositol 3-Kinases|Neoplasm Recurrence, Local|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Disease-Free Survival|Cell Proliferation|Cell Line, Tumor|Remission Induction|S100 Proteins|Signal Transduction|*Relapse|B-Lymphocytes|S100A16 protein, human 46 SALL3 31746370 Int. J. Oncol. 2019 10.3892/ijo.2019.4915 1 3 0 122 *Thymoma|*Growth Hormone Secretagogue Receptor|*DNA Methylation|*B-DNA|Thymic epithelial tumor|Thymus Neoplasms|CpG Islands|Promoter Regions, Genetic|Neoplasms, Glandular and Epithelial|Tumor Suppressor Proteins|*Epigenetic|Carcinogenesis|Carcinoma|Epigenesis, Genetic 61 SALL3 31699190 Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2019 10.3881/j.issn.1000-503X.11533 0 2 0 122 Humans|Female|*Uterine Cervical Neoplasms|DNA Methylation|Papillomavirus Infections|Human papillomavirus 16|Cervix Uteri|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|mRNA|Down-Regulation|SALL3 protein, human|Transcription Factors|Homeodomain Proteins 61 SALL3 31506333 Cancer Res. 2019 10.1158/0008-5472.CAN-19-0991 0 0 0 122 Carcinoma, Hepatocellular|Liver Neoplasms|*Epigenomics|*Transcriptome|*Carcinogenesis|Liver Cirrhosis|Gene Expression Regulation, Neoplastic|*Genomics|Gene Expression Profiling|Disease Progression|Biomarkers, Tumor|Precancerous Conditions|DNA Methylation 61 SALL3 31350846 Biol. Reprod. 2019 PMC6877779 10.1093/biolre/ioz137 0 0 0 122 Female|Animals|*Chicken|Granulosa Cells|Ovarian Follicle|*Cell Proliferation|mRNA|Cell Differentiation|Oocytes|siRNA 61 SALL3 31327173 Mol Nutr Food Res 2019 10.1002/mnfr.201801386 4 0 0 122 *Transcription Factor|*Semaphorin-3A|DNA Methylation|*Epigenetic|DNA (Cytosine-5-)-Methyltransferases|CpG Islands|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Gene Silencing|*DNA Modification Methylases|*DNA|Chromatin|Cell Line, Tumor|pterostilbene|*Stilbenoids 61 SALL3 31271297 Artif Cells Nanomed Biotechnol 2019 10.1080/21691401.2019.1634578 1 0 0 122 Humans|Female|*Uterine Cervical Neoplasms|5-hydroxymethylcytosine|5-Methylcytosine|DNA Methylation|Epigenetic|Epigenesis, Genetic|Gene Expression Regulation|Genome|Downregulation|DNA|Signal Transduction|CDC14B protein, human|Dual-Specificity Phosphatases 61 SALL3 31188017 DNA Cell Biol. 2019 10.1089/dna.2018.4597 2 1 0 122 Neoplasm Recurrence, Local|Mouth Neoplasms|Head and Neck Squamous Cell Carcinoma|Head and Neck Neoplasms|Promoter Regions, Genetic|Carcinoma, Squamous Cell|CpG Islands|DNA Methylation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 61 SALL3 31092818 Nat Commun 2019 PMC6520385 10.1038/s41467-019-09511-4 0 4 0 122 Humans|*Induced Pluripotent Stem Cells|*Cell Differentiation|Lineages, Cell|Cellular Reprogramming|Endoderm|Cell Line|Homeodomain Proteins|DNA Methylation|Cells, Cultured|Fibroblasts|Mesoderm|*Biases|SALL3 protein, human|Transcription Factors 61 SALL3 31089300 Nat Hum Behav 2019 10.1038/s41562-019-0557-y 3 0 0 122 Humans|*Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Linkage Disequilibrium|Genetic Loci|*Smoking Behavior|European Continental Ancestry Group|Case-Control Studies|Cigarette Smoking|Risk Factor 61 SALL3 30901947 Cancers (Basel) 2019 PMC6468360 10.3390/cancers11030401 1 2 0 122 Humans|*Prognosis|*Head and Neck Cancer|DNA Methylation|Promoter Regions, Genetic|Squamous Cell Carcinoma of Head and Neck|Carcinoma, Squamous Cell|CpG Islands|Receptor, Galanin, Type 2|Receptor, Galanin, Type 1|Epigenesis, Genetic|Biomarkers, Tumor|*Epigenetic|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Cell Line, Tumor 61 SAMD9 31646435 Neurosci Bull 2019 PMC7142204 10.1007/s12264-019-00436-y 0 0 0 94 Humans|Adult|Phosphatidylinositol 3-Kinases|*Genes, Homeobox|*Sterile Alpha Motif|*Glioma|Glioblastoma|Brain Cancer|*Disease Progression|Epithelial-Mesenchymal Transition|Proto-Oncogene Proteins c-akt|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|SAMD9 protein, human|Cell Proliferation|*Genes, Regulator 84 SAMD9 31638924 BMC Pediatr 2019 PMC6802302 10.1186/s12887-019-1733-y 0 0 0 94 Humans|*Diagnosis, Dual (Psychiatry)|*Deglutition Disorders|Anemia, Megaloblastic|Thiamine Deficiency|*Mutations|*Phenotypes|Thiamine|Hearing Loss, Sensorineural|SAMD9 protein, human|Membrane Transport Proteins|*Genes, Regulator|Diabetes Mellitus|*Infections|SLC19A2 protein, human 84 SAMD9 31624021 Trends Mol Med 2019 10.1016/j.molmed.2019.08.008 0 0 0 94 SAMD9 protein, human|Myelodysplastic Syndromes|Mutations|Adrenal Insufficiency|Intracellular Signaling Peptides and Proteins|Heterozygote 84 SAMD9 31620126 Front Immunol 2019 PMC6759462 10.3389/fimmu.2019.02194 0 0 0 94 Humans|SAMD9 protein, human|*Immunologic Deficiency Syndromes|Myelodysplastic Syndromes|*Neutropenia|Mutations|Intracellular Signaling Peptides and Proteins|Adrenal Insufficiency 84 SAMD9 31610036 Clin. Endocrinol. (Oxf) 2019 PMC6916405 10.1111/cen.14109 2 0 0 94 Humans|Adolescent|Adult|Child|*Addison Disease|Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, And Genital Anomalies|*Adrenal Insufficiency|NR0B1 protein, human|Nuclear Receptor DAX 1|NR5A1 protein, human|Steroidogenic Factor 1|Congenital Adrenal Hyperplasia|Transcription Factors|Phenotype|Fetal Growth Retardation|Osteochondrodysplasias|SAMD9 protein, human|Proteins 84 SAMD9 31597823 Rinsho Ketsueki 2019 10.11406/rinketsu.60.1020 0 0 0 94 Humans|Child|Mice|Animals|Chromosome 7, monosomy|*Chromosomes, Human, Pair 7|*Chromosome Deletion|Myelodysplastic Syndromes|Myeloproliferative Disorders|SAMD9 protein, human|EZH2 protein, human|Enhancer of Zeste Homolog 2 Protein|Tumor Suppressor Proteins|Nuclear Proteins|Haploinsufficiency|Repressor Proteins|Intracellular Signaling Peptides and Proteins|Pancytopenia|Tumor 84 SAMD9 31572304 Front Endocrinol (Lausanne) 2019 PMC6749008 10.3389/fendo.2019.00625 1 0 0 94 84 SAMD9 31535357 J. Endocrinol. Invest. 2019 10.1007/s40618-019-01097-4 0 0 0 94 Humans|*Calcinosis|SAMD9 protein, human|Proteins|*Genetic Testing|Mutation 84 SAMD9 31306780 Biol. Blood Marrow Transplant. 2019 PMC7110513 10.1016/j.bbmt.2019.07.007 1 4 0 94 Humans|Infant|Child, Preschool|Child|*Mutations, Germline|Retrospective Studies|SAMD9 protein, human|Myelodysplastic Syndrome|*Hematopoietic Stem Cell Transplantation|Pancytopenia|Leukemia, Myeloid, Acute|Tumor Suppressor Proteins|Mutation|Chromosome Deletion|Intracellular Signaling Peptides and Proteins|*Genes, Regulator|Heterozygote|Hypoadrenocorticism, Familial|Congenital amegakaryocytic thrombocytopenia|Thrombocytopenia|Congenital Bone Marrow Failure Syndromes|Germ Cells 84 SAMD9 31281163 Rinsho Ketsueki 2019 10.11406/rinketsu.60.702 0 0 0 94 Child|Humans|*Bone Marrow Failure Disorders|*Primary Immunodeficiency Diseases|Myelodysplastic Syndrome|Anemia, Aplastic|Bone Marrow Diseases|Hemoglobinuria, Paroxysmal|Leukemia, Myeloid, Acute|MonoMac Syndrome|*Inherited Bone Marrow Failure Syndromes|Chromosome 7, monosomy|Chromosome Deletion|Mutation|Genetic Predisposition to Disease|DNA Repair|*Genotype|Chromosome 7|SAMD9 protein, human|Proteins 84 SAMD9 31281151 Rinsho Ketsueki 2019 10.11406/rinketsu.60.600 1 0 0 94 Humans|Aged|*Myelodysplastic Syndromes|Myelodysplastic-Myeloproliferative Diseases|Leukemia, Myeloid, Acute|Mutations|Myeloproliferative Disorders|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|*Genomics|Mutation Frequency|Sequencing, Next-Generation|Disease Progression|Neoplasms, Hematological|SAMD9 protein, human|Proteins 84 SAMD9 31208161 J Clin Res Pediatr Endocrinol 2019 PMC7291401 10.4274/jcrpe.galenos.2019.2019.0053 1 0 0 94 Humans|*Adrenal Insufficiency|*Mutations|SAMD9 protein, human|Myelodysplastic Syndromes|Hypoadrenocorticism, Familial|Phenotypes|Intracellular Signaling Peptides and Proteins|Heterozygote|*Sex Development 84 SAMD9 30918078 J. Virol. 2019 PMC6613757 10.1128/JVI.00225-19 2 1 0 94 Humans|Cricetinae|Mice|Animals|*Orthopoxvirus|*Rodent|CHO Cells|Cricetulus|SAMD9 protein, human|Vaccinia virus|Cowpox virus|Vaccinia|Viral Proteins|Host Range|Virus Replication|Monkeypoxvirus|Intracellular Signaling Peptides and Proteins|Host-Pathogen Interactions|HeLa Cells|*Genes, Regulator 84 SAMD9L 31874111 J. Clin. Invest. 2019 PMC7108905 10.1172/JCI129301 4 0 0 71 Humans|*Cytokines|Hereditary Autoinflammatory Diseases|Interferon|Mutations|interleukin 18 protein, human|IL-18|Autoimmune Diseases|Macrophage Activation Syndrome|Inflammation|Nervous System Malformations|three prime repair exonuclease 1|Exodeoxyribonucleases|Phosphoproteins|Phenotypes|IKBKG protein, human|I-kappa B Kinase 43 SAMD9L 31665046 Virol. J. 2019 PMC6819563 10.1186/s12985-019-1231-8 0 0 0 71 Humans|Child|*Influenza, Human|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Computational Biology|Databases, Genetic|*Biomarkers|Cluster Analysis|Transcriptome 43 SAMD9L 31597823 Rinsho Ketsueki 2019 10.11406/rinketsu.60.1020 0 0 0 71 Humans|Child|Mice|Animals|Chromosome 7, monosomy|*Chromosomes, Human, Pair 7|*Chromosome Deletion|Myelodysplastic Syndromes|Myeloproliferative Disorders|SAMD9 protein, human|EZH2 protein, human|Enhancer of Zeste Homolog 2 Protein|Tumor Suppressor Proteins|Nuclear Proteins|Haploinsufficiency|Repressor Proteins|Intracellular Signaling Peptides and Proteins|Pancytopenia|Tumor 43 SAMD9L 31306780 Biol. Blood Marrow Transplant. 2019 PMC7110513 10.1016/j.bbmt.2019.07.007 1 4 0 71 Humans|Infant|Child, Preschool|Child|*Mutations, Germline|Retrospective Studies|SAMD9 protein, human|Myelodysplastic Syndrome|*Hematopoietic Stem Cell Transplantation|Pancytopenia|Leukemia, Myeloid, Acute|Tumor Suppressor Proteins|Mutation|Chromosome Deletion|Intracellular Signaling Peptides and Proteins|*Genes, Regulator|Heterozygote|Hypoadrenocorticism, Familial|Congenital amegakaryocytic thrombocytopenia|Thrombocytopenia|Congenital Bone Marrow Failure Syndromes|Germ Cells 43 SAMD9L 31281163 Rinsho Ketsueki 2019 10.11406/rinketsu.60.702 0 0 0 71 Child|Humans|*Bone Marrow Failure Disorders|*Primary Immunodeficiency Diseases|Myelodysplastic Syndrome|Anemia, Aplastic|Bone Marrow Diseases|Hemoglobinuria, Paroxysmal|Leukemia, Myeloid, Acute|MonoMac Syndrome|*Inherited Bone Marrow Failure Syndromes|Chromosome 7, monosomy|Chromosome Deletion|Mutation|Genetic Predisposition to Disease|DNA Repair|*Genotype|Chromosome 7|SAMD9 protein, human|Proteins 43 SAMD9L 31281151 Rinsho Ketsueki 2019 10.11406/rinketsu.60.600 1 0 0 71 Humans|Aged|*Myelodysplastic Syndromes|Myelodysplastic-Myeloproliferative Diseases|Leukemia, Myeloid, Acute|Mutations|Myeloproliferative Disorders|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|*Genomics|Mutation Frequency|Sequencing, Next-Generation|Disease Progression|Neoplasms, Hematological|SAMD9 protein, human|Proteins 43 SAMD9L 31053103 BMC Neurol 2019 PMC6499956 10.1186/s12883-019-1319-1 0 0 0 71 Humans|*Dilatation, Pathologic|*Peripheral Neuropathy|Phenotype|Exome|Leukoencephalopathies|Myelocerebellar Disorder|Cerebellar Ataxia|Mutation|*Nervous System Malformations|Mutations, Missense|Pancytopenia|Demyelinating Diseases|Basal Ganglia 43 SAMD9L 31015479 Nat Commun 2019 PMC6478738 10.1038/s41467-019-09637-5 9 0 0 71 Humans|*Genome, Human|*Nanopores|High-Throughput Nucleotide Sequencing|Sequence Analysis, DNA|Genomics|Computational Biology|Sequencing, Whole Genome|Haplotype|Polymorphism, Single Nucleotide 43 SAMD9L 30971808 Pharmacogenomics J. 2019 10.1038/s41397-019-0085-1 2 1 0 71 Child|Infant|Humans|*Mucocutaneous Lymph Node Syndrome|*Genome-Wide Association Study|*Immunoglobulins, Intravenous|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genetic Loci|Genotype|Odds Ratio|Inflammation 43 SAMD9L 30918078 J. Virol. 2019 PMC6613757 10.1128/JVI.00225-19 2 1 0 71 Humans|Cricetinae|Mice|Animals|*Orthopoxvirus|*Rodent|CHO Cells|Cricetulus|SAMD9 protein, human|Vaccinia virus|Cowpox virus|Vaccinia|Viral Proteins|Host Range|Virus Replication|Monkeypoxvirus|Intracellular Signaling Peptides and Proteins|Host-Pathogen Interactions|HeLa Cells|*Genes, Regulator 43 SAMSN1 31875116 J Lasers Med Sci 2019 PMC6885903 10.15171/jlms.2019.42 6 0 0 51 25 SAMSN1 31863085 Sci Rep 2019 PMC6925116 10.1038/s41598-019-56047-0 0 0 0 51 Humans|*Platelets|*Myocardial Infarction|Coronary Atherosclerosis|Coronary Thrombosis|ST Segment Elevation Myocardial Infarction|Atherosclerotic Plaque|Megakaryocytes|Logistic Regression|*Gene Expression|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport 25 SBSN 31399284 J. Dermatol. Sci. 2019 10.1016/j.jdermsci.2019.07.009 0 3 0 57 *Keratinocytes|*Dermatitis, Atopic|*Epidermis|*Cell Differentiation|*Eczema|Skin|Th2 Cells|Cytokines|Cells, Cultured|*Apoptosis 23 SBSN 31276031 BMJ Open Ophthalmol 2019 PMC6579564 10.1136/bmjophth-2018-000254 0 0 0 57 Humans|*Stevens-Johnson Syndrome|Conjunctival Diseases|Conjunctiva|*Epithelium 23 SBSN 30919591 Mol Oncol 2019 PMC6599850 10.1002/1878-0261.12480 0 6 0 57 Mice|Female|Animals|Humans|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Signal Transduction|Neoplasm Proteins|Cell Line, Tumor|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|Interferon|Upregulation|5 Azacytidine|Cell Proliferation|MEK-ERK Pathway|Anoikis|Mitogen-Activated Protein Kinase Kinases|*Stem Cell|Ovarian Neoplasms 23 SCAF1 31511525 Nat Commun 2019 PMC6739376 10.1038/s41467-019-12124-6 6 0 0 104 Humans|*Mitochondria|*Tumorigenesis|*Hypoxia|Oxidative Phosphorylation|Electron Transport Complex IV|2 Oxoglutarate Dehydrogenase Complex|Reactive Oxygen Species|Cell Transformation, Neoplastic|Cell Line, Tumor|*Biochemical Phenomena|Metabolic Profile 28 SCAF1 31455568 Trends Endocrinol. Metab. 2019 10.1016/j.tem.2019.08.003 0 0 0 104 EIF-2|Endoplasmic Reticulum Stress|*Mitochondria|eIF-2 Kinase|Activating Transcription Factor 4|Signal Transduction|Apoptosis|Bioenergetics 28 SCAF1 31308072 J. Am. Soc. Nephrol. 2019 PMC6727251 10.1681/ASN.2019020152 3 0 0 104 *Glomerulosclerosis, Focal Segmental|Genetic Predisposition to Disease|Mutation|Case-Control Studies 28 SCAF1 31023583 Mol. Cell 2019 PMC6555668 10.1016/j.molcel.2019.03.031 17 7 0 104 Humans|*EIF-2|*Electron Transport|Endoplasmic Reticulum Stress|eIF-2 Kinase|Activating Transcription Factor 4|Unfolded Protein Response|Signal Transduction|Phosphorylation|Endoplasmic Reticulum|Cell Survival|*Nutrient|Apoptosis|*Mitochondrial Membranes 28 Scara3 31653705 J. Biol. Chem. 2019 PMC6901321 10.1074/jbc.RA119.010110 0 3 0 1145 *Spectrin|*Scavenger Receptor|Scavenger Receptors, Class A|Macrophages|Receptors, Immunologic|Cell Membrane 37 Scara3 31577778 Medicine (Baltimore) 2019 PMC6783241 10.1097/MD.0000000000017471 0 0 0 1145 Humans|*Hand, Foot and Mouth Disease|*Case-Control Studies|Enterovirus A, Human|*Scavenger Receptor|China|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Biomarkers 37 Scara3 31565488 Cancer Biol Med 2019 PMC6743613 10.20892/j.issn.2095-3941.2018.0277 1 0 0 1145 *Glioblastoma|*Prognosis|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Transcriptome|Biomarkers, Tumor 37 Scara3 30820289 J Ophthalmic Vis Res 2019 PMC6388514 10.4103/jovr.jovr_80_18 5 8 0 1145 Humans|*Keratoconus|*Oxidants|Cornea|*Damage, Corneal|Reactive Nitrogen Species|*Oxidation-Reduction|Reactive Oxygen Species|Oxidative Stress|DNA, Mitochondrial|Fibroblasts|Blotting, Western|Superoxide Dismutase|FOXM1 protein, human|Forkhead Box Protein M1|PRDX6 protein, human|Peroxiredoxin VI 37 Scara3 30804981 Front Genet 2019 PMC6371051 10.3389/fgene.2019.00036 2 4 0 1145 Animals|Female|*Buffaloes|*Milk|*Genome-Wide Association Study|*Transcriptome|Lactation|*Phenotype|Mammary Glands, Animal|*Bison 37 SCPEP1 31469189 Mol. Carcinog. 2019 PMC6852404 10.1002/mc.23101 1 3 0 445 Mice|Animals|*RNA, Small Nucleolar|MIRN137 microRNA, human|*MicroRNAs|*Colorectal Cancer|Cell Proliferation|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Carcinogenesis|Cell Movement|*Disease Progression|Cell Line, Tumor|Apoptosis|serum-inducible kinase|Serine Threonine Kinase|Down-Regulation|Upregulation|PLK2 protein, human|*Colonic Neoplasms 47 SCPEP1 31098994 Methods Mol. Biol. 2019 10.1007/978-1-4939-9220-1_4 0 0 0 445 Humans|*RNA, Small Interfering|AGO2 protein, human|*Argonaute Proteins|RNA-Induced Silencing Complex|RNA Interference|*Double-Stranded RNA|Ribonuclease III|HeLa Cells|Kinetics 47 SCRN1 31842489 Cancers (Basel) 2019 PMC6966585 10.3390/cancers11122006 0 0 0 65 Humans|Female|Dogs|Animals|Genome-Wide Association Study|Mammary Neoplasms, Animal|Class I Phosphatidylinositol 3-Kinases|Phosphatidylinositol 3-Kinases|Mammary Neoplasms, Experimental|Gene Expression Regulation, Neoplastic|Mutation 21 SCRN1 31796108 Acta Neuropathol Commun 2019 PMC6892024 10.1186/s40478-019-0848-6 0 2 0 65 Humans|*Alzheimer Disease|*Tauopathies|Neurofibrillary Tangles|Pick Disease|tau Proteins|Progressive Supranuclear Palsy|Frontotemporal Lobar Degeneration|Neurons|Phosphorylation|Brain|Immunohistochemistry|Down Syndrome|Basal Ganglia Diseases|Inclusion Bodies|Plaque, Amyloid|*Biophysical Phenomena|SCRN1 protein, human|Nerve Tissue Proteins 21 SCRN1 31441084 EMBO J. 2019 PMC6792018 10.15252/embj.2018101345 4 3 0 65 Animals|*Endoplasmic Reticulum|VAPB protein, human|*Vesicular Transport Proteins|Carrier Proteins|Membrane Proteins|Neurons|Protein Binding|Biological Transport|Axons 21 SDHAF2 31773218 World J Surg 2019 10.1007/s00268-019-05299-y 1 0 0 134 Humans|*Pheochromocytoma|*von Hippel-Lindau Disease|*Adrenal Gland Neoplasms|Von Hippel-Lindau Tumor Suppressor Protein|Germ-Line Mutation|Proto-Oncogene Proteins c-ret|Genetic Predisposition to Disease 125 SDHAF2 31744495 J Transl Med 2019 PMC6865056 10.1186/s12967-019-02140-x 2 0 0 134 Humans|Female|*Prognosis|*Alternative Splicing|*Uterine Cervical Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Gene Regulatory Networks|RNA, Messenger|Kaplan-Meier Estimate|ROC Curve 125 SDHAF2 31705439 Endocr. Pathol. 2019 10.1007/s12022-019-09594-1 0 0 0 134 Middle Aged|Male|Humans|*Paraganglioma|Pheochromocytomas|Adrenal Gland Neoplasms|Succinate Dehydrogenase|Mutations, Germline|*Mutations|Neoplastic Syndromes, Hereditary|Genetic Testing|Heterozygote|*Pelvis, Renal|Membrane Proteins|ATRX protein, human|X-linked Nuclear Protein|SDHB protein, human 125 SDHAF2 31687641 J Endocr Soc 2019 PMC6821206 10.1210/js.2018-00353 0 0 0 134 Humans|*Carotid Body Tumor|*Thyroid Gland|SDHD protein, human|Succinate Dehydrogenase|Paragangliomas|Pheochromocytomas|Adrenal Gland Neoplasms|*Thyroid Neoplasms|Germ-Line Mutation|Genetic Testing|Head and Neck Neoplasms 125 SDHAF2 31666924 Oncotarget 2019 PMC6800268 10.18632/oncotarget.27194 0 0 0 134 Humans|*Paraganglioma|Pheochromocytoma|Adrenal Gland Neoplasms|*Genotype-Phenotype Correlation|Mutations, Germline|Succinate Dehydrogenase|*Mutations|Genetic Testing|Genetic Predisposition to Disease|Membrane Proteins|Phenotype|Saudi Arabia 125 SDHAF2 31649053 J. Med. Genet. 2019 10.1136/jmedgenet-2019-106324 0 1 0 134 *Pheochromocytoma|*Paraganglioma|SDHD protein, human|Succinate Dehydrogenase|*Adrenal Gland Neoplasms|Mutation|Germ-Line Mutation|Membrane Proteins|*Neoplasms, Second Primary 125 SDHAF2 31372201 Int J Hematol Oncol Stem Cell Res 2019 PMC6660475 0 0 0 134 *Succinate|SDHD protein, human|Succinate Dehydrogenase|Paraganglioma|Pheochromocytoma|Adrenal Gland Neoplasms|*Cell Transformation, Neoplastic|Mutation|*Tumorigenesis|Neoplastic Syndromes, Hereditary|Germ-Line Mutation|Membrane Proteins 125 SDHAF2 31348302 Medicine (Baltimore) 2019 PMC6708967 10.1097/MD.0000000000016594 0 0 0 134 Humans|*Pheochromocytoma|*Pituitary Neoplasms|*Paragangliomas|*Adrenal Gland Neoplasms|SDHD protein, human|Succinate Dehydrogenase|*Adenoma|*Mutation 125 SDHAF2 31046099 J. Clin. Endocrinol. Metab. 2019 10.1210/jc.2019-00175 0 0 0 134 *Paraganglioma|*Germline Mutation|Succinate Dehydrogenase|Pheochromocytoma|Adrenal Gland Neoplasms|*Phenotype|Heterozygote|Genotype|Head and Neck Neoplasms|Membrane Proteins|Germ Line 125 SDHAF2 30971719 Sci Rep 2019 PMC6458311 10.1038/s41598-019-42338-z 1 1 0 134 SDHD protein, human|*Succinate Dehydrogenase|*Hemangioblastoma|Paraganglioma|Pheochromocytoma|Germ-Line Mutation|Immunohistochemistry|Mutations|Membrane Proteins|Adrenal Gland Neoplasms|Nervous System 125 SEC14L2 31882500 In Vivo 2019 PMC6984093 10.21873/invivo.11782 0 0 0 336 Humans|*Twins, Monozygotic|*DNA Methylation|*B-DNA|CpG Islands|Epigenesis, Genetic|Promoter Regions, Genetic|Genome, Human|Phenotype|Genetic Predisposition to Disease|*Myocardial Infarction 55 SEC14L2 31854467 Microbiol. Immunol. 2019 10.1111/1348-0421.12768 0 0 0 336 Humans|*Hepatitis C virus|*Hepatitis C|Replicon|Virus Replication|RNA, Viral|Genome, Viral|*Cell Culture|Genotype|Transfection|Luciferase|Cell Line, Tumor|Mutations|Clone Cells|*Immunologic Tests 55 SEC14L2 31851620 Aging (Albany NY) 2019 PMC6949064 10.18632/aging.102579 0 0 0 336 Humans|*Carcinoma, Hepatocellular|*Liver Cancer|Prognosis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Disease Progression|Transcriptome|Transcriptional Networks|SEC14L2 protein, human|Carrier Proteins|Lipoproteins|Trans-Activators 55 SEC14L2 31128610 Respir Med 2019 10.1016/j.rmed.2019.04.021 1 0 0 336 Humans|*Sputum|*Anti-Inflammatory Agents, Non-Steroidal|*Desensitization, Immunologic|Asthma, Aspirin-Induced|Aspirin|*Respiration Disorders|*Biomarkers|Asthma 55 SEC14L2 30962435 Nat Commun 2019 PMC6453981 10.1038/s41467-019-09604-0 0 56 0 336 Animals|*Zebrafish|Vascular Endothelial Growth Factor A|KDR protein, human|VEGFR-2|*Signal Transduction|Zebrafish Proteins|Neovascularization, Physiologic|Human Umbilical Vein Endothelial Cells|Carrier Proteins|Cell Movement|*Morphogenesis|*Cell Differentiation|Phosphatidylinositol Transfer Proteins 55 SEC14L2 30704470 BMC Med Genomics 2019 PMC6357449 10.1186/s12920-018-0467-2 2 0 0 336 Humans|*Glucocorticoids|*Transcriptome|NR3C1 protein, human|Glucocorticoid Receptor|*Cells, Epithelial|*Cell Lines|Adrenergic beta-2 Receptor Agonists|Asthma|Bronchi|Respiratory Mucosa|Transcription, Genetic|Corticosteroids 55 SEMA3C 31861264 Cells 2019 PMC7017238 10.3390/cells9010003 0 0 0 263 Humans|Male|*Receptors, Glucocorticoid|Prostate Cancer|Androgen Antagonists|AR protein, human|Androgen Receptor|CD100 antigen|Semaphorins|Prostate|Antigens, CD|Cell Nucleus|Nerve Tissue Proteins|Cell Motility|Mutation 133 SEMA3C 31726800 Int J Mol Sci 2019 PMC6888630 10.3390/ijms20225672 1 0 0 263 Animals|Chick Embryo|*Chorioallantoic Membrane|Glioblastoma|Neovascularization, Pathologic|*Tumorigenesis|Neovascularization Inhibitors|Cell Line, Tumor|Semaphorins|Cell Proliferation|Chicken|Sodium Valproate 133 SEMA3C 31649890 Front Oncol 2019 PMC6794562 10.3389/fonc.2019.01035 1 0 0 263 133 SEMA3C 31492046 Int J Mol Sci 2019 PMC6770352 10.3390/ijms20184371 2 0 0 263 Humans|*Chondrogenesis|*hiPSC|MIRN629 microRNA, human|*MicroRNAs|MIRN628 microRNA, human|MIRN525 microRNA, human|Cell Differentiation|Chondrocytes|Transcriptome Analysis|Cells, Cultured|Profile, Gene Expression 133 SEMA3C 31300520 J. Neurosci. 2019 PMC6703882 10.1523/JNEUROSCI.0278-19.2019 4 2 0 263 Animals|Mice|*Activated-Leukocyte Cell Adhesion Molecule|*Dopaminergic Neurons|*Cell Adhesion|*Mesencephalon|ALCAM protein, human|*Cell Adhesion Molecules, Neuronal|*Cell Adhesion Molecules|Axons|*Fetal Proteins|*Antigens, CD|Growth Cone|Semaphorins|Dopamine|Gene Expression Regulation, Developmental|Signal Transduction 133 SEMA3C 31240788 Neurogastroenterol. Motil. 2019 10.1111/nmo.13665 0 0 0 263 *Hirschsprung Disease|Taiwan|*DNA Mutational Analysis|Proto-Oncogene Proteins c-ret|Pedigree|Genetic Predisposition to Disease|Mutation|Polymerase Chain Reaction 133 SEMA3C 31020999 J. Pathol. 2019 PMC6766969 10.1002/path.5284 1 0 0 263 Humans|*Axon Guidance|EWSR1 protein, human|*RNA-Binding Protein EWS|Chondrosarcoma, Extraskeletal Myxoid|*Chondrosarcoma|Neoplasms, Connective and Soft Tissue|Receptors, Thyroid Hormone|TAF15 protein, human|*TATA-Binding Protein Associated Factors|*Translocation, Genetic|Receptors, Steroid|DNA-Binding Proteins|Calmodulin-Binding Proteins|Oncogene Proteins, Fusion|Sarcoma|Soft Tissue Neoplasms|TYRP1 protein, human|*Membrane Glycoproteins 133 SEMA3C 30930637 Turk. J. Biol. 2019 PMC6426645 10.3906/biy-1808-58 0 3 0 263 Humans|*HMGA2 Protein|*Signal Transduction|ACKR3 protein, human|*Receptors, CXCR|CXCL14 protein, human|*Chemokines, CXC|Receptor, Notch1|MCF-7 Cells|Receptors, Notch|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|CCL20 protein, human|*Chemokine CCL20|Sema3C protein, human|Semaphorins 133 SEMA3C 30794985 J Mol Diagn 2019 PMC6504676 10.1016/j.jmoldx.2019.01.009 0 0 0 263 Humans|*Genotype|Genotyping Techniques|Pharmacogenetics|Pharmacogenetic Testing|FCGR3A protein, human|Receptors, IgG|Genetic Testing|FCGR2A protein, human|*Medical Oncology 133 SEMA3C 30759745 Int J Mol Sci 2019 PMC6386986 10.3390/ijms20030774 3 0 0 263 Humans|Male|*Prostate|Semaphorins|Prostate Cancer|Cell Proliferation|Cell Movement|Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Anticancer Agents 133 SERPINA6 30867825 Theranostics 2019 PMC6401414 10.7150/thno.31991 1 2 0 697 Humans|*Acute-On-Chronic Liver Failure|*Proteomics|Hepatitis B, Chronic|Hepatitis B virus|ROC Curve|Prognosis|Case-Control Studies|Severity of Illness Index|Risk Assessment 94 SERPINA6 30776573 Psychoneuroendocrinology 2019 10.1016/j.psyneuen.2019.02.002 1 0 0 697 Pregnancy|Humans|Female|*Peripartum Period|*Depression|Pituitary-Adrenal System|Hypothalamo-Hypophyseal System|Cortisol|Post-Partum Depression|Postpartum Period|Stress, Psychological|Cortisone|Single Nucleotide Polymorphisms|Edinburgh Postnatal Depression Scale|Personality|Genetic Variation|Genotypes 94 SERPINB5 31588320 Chem Sci 2019 PMC6761875 10.1039/c9sc01432b 4 0 0 751 *Dendrimers|CRISPR-Associated Protein 9|CRISPR-Cas Systems|CRISPR|Transcription Factors|Cell Line, Tumor|Gene Expression 102 SERPINB5 31157588 Cell Cycle 2019 PMC6619930 10.1080/15384101.2019.1618122 3 0 0 751 *Stomach Neoplasms|*RNA, Circular|miRNA|*Disease Progression|Gene Expression Regulation, Neoplastic|Downregulation|*Stomach|Cell Proliferation|mRNA|Cell Movement|*Neoplastic Processes|Cell Line, Tumor|Signal Transduction|Oncogenesis|SERPIN-B5|Serpins 102 SERPINB5 31059004 Int. J. Oncol. 2019 PMC6561627 10.3892/ijo.2019.4796 0 4 0 751 Humans|*Histone Deacetylase Inhibitors|*Triple Negative Breast Neoplasms|*Genes, Tumor Suppressor|entinostat|Benzamides|Pyridines|Histone Deacetylases|Twist-Related Protein 1|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Cell Differentiation|Xenograft Model Antitumor Assays|Cell Proliferation|Angiogenesis Inhibitors|MCF7 Cells|Apoptosis|Genes, Regulator 102 SERPINB5 31036418 Am J Otolaryngol 2019 10.1016/j.amjoto.2019.04.015 0 0 0 751 Humans|*Papillomavirus Infections|*Computational Biology|*Oropharyngeal Neoplasms|*Mouth Neoplasms|Carcinoma, Squamous Cell|*Squamous Cell Carcinoma of Head and Neck|Papillomaviridae|MicroRNAs|Cell Line, Tumor|Head and Neck Neoplasms 102 SERPINB5 31034786 Reprod. Fertil. Dev. 2019 10.1071/RD18438 0 5 0 751 Pregnancy|Humans|Female|*Vascular Endothelial Growth Factor C|SERPIN-B5|*Serpins|*Trophoblasts|*Vascular Endothelial Growth Factor B|Vascular Endothelial Growth Factor A|Cell Migration|DNA Methylation|Gene Expression|Pre-Eclampsia|Cells, Cultured|Upregulation|Downregulation 102 SERPINB5 30639415 EBioMedicine 2019 PMC6412825 10.1016/j.ebiom.2019.01.003 5 11 0 751 Humans|Pancreatic Carcinoma|*Prognosis|*Pancreatic Neoplasms|Gene Ontology|Protein Interaction Maps|Computational Biology|Gene Expression Profiling|Gene Regulatory Networks|Databases, Genetic|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Transcriptome|Kaplan-Meier Estimate 102 SERPINB7 31841397 Physiol. Genomics 2019 PMC7052568 10.1152/physiolgenomics.00098.2019 0 0 0 30 Female|Mice|Animals|EZH2 protein, human|*Enhancer of Zeste Homolog 2 Protein|*Transcriptome|*Uterus|Glandular Epithelial Cells|Estradiol|Estrogen Receptor alpha|Cell Proliferation|Stromal Cells 57 SERPINB9 31704833 Anticancer Res. 2019 10.21873/anticanres.13813 0 0 0 198 *Prognosis|*Serpins|*Colorectal Cancer|Biomarkers, Tumor|Neoplasm Staging|Lymphatic Metastasis|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Cell Proliferation|Cell Movement|Survival Rate|Tumor Cells, Cultured|RNA, Messenger|Apoptosis|Real-Time Polymerase Chain Reaction 133 SERPINB9 31483286 J. Clin. Invest. 2019 PMC6763250 10.1172/JCI127458 3 1 0 198 Mice|Animals|CD8-Positive T-Lymphocytes|Cytotoxicity, Immunologic|Melanoma, Experimental|CD274 protein, human|B7-H1 Antigen|Interferon Type I|*Apoptosis|Tumor Microenvironment|Signal Transduction|Mice, Inbred C57BL|Immunity, Innate|Serpinb9 protein, mouse|Membrane Proteins|Serpins 133 SERPINB9 31059128 Clin. Exp. Immunol. 2019 PMC6693965 10.1111/cei.13309 0 2 0 198 Humans|*Cancer, Skin|Carcinoma, Squamous Cell|*T Cells|Neoplasm Recurrence, Local|Organ Transplantation|*Transplant|DNA Methylation|Kidney Transplantation|Immunosuppressive Agents|Cohort Studies|*Skin|SERPINB9 protein, human|Serpins 133 SERPINF1 31882638 Sci Rep 2019 PMC6934745 10.1038/s41598-019-56007-8 0 0 0 1508 Animals|*Hibernations|*Ursidae|*Proteomics|*Transcriptome|Caenorhabditis elegans|*Muscle Atrophy|Muscle, Skeletal|Muscle Contraction|Heart Rate 130 SERPINF1 31715670 Zhonghua Yi Xue Za Zhi 2019 10.3760/cma.j.issn.0376-2491.2019.42.011 0 0 0 1508 130 SERPINF1 31676463 Prog. Neuropsychopharmacol. Biol. Psychiatry 2019 10.1016/j.pnpbp.2019.109792 0 0 0 1508 Humans|Mice|Rats|Animals|pigment epithelium-derived factor|*Wnt Signaling Pathway|Depressive Disorder, Major|*C57BL Mice|*Serpins|*Eye Proteins|*Hippocampus|Brain-Derived Neurotrophic Factor|Stress, Psychological|Depression|Disease Models, Animal 130 SERPINF1 31518731 Theriogenology 2019 10.1016/j.theriogenology.2019.09.003 0 0 0 1508 Male|Humans|Cats|Animals|*Semen|*Proteome|*Urinary Catheterization|*Felis|Semen Analysis|Spermatozoa|Seminal Plasma Proteins|Sperm Motility|Cryopreservation|*Bodily Secretions|*Body Fluids|SDS PAGE 130 SERPINF1 31429852 Genet. Mol. Biol. 2019 PMC6726155 10.1590/1678-4685-GMB-2018-0043 0 0 0 1508 Humans|*Osteogenesis Imperfecta|Genes, Recessive|Mutation|Collagen Type I|Genotype|Brazil|FKBP10 protein, human|Tacrolimus Binding Proteins 130 SERPINF1 31204718 J. Genet. 2019 0 0 0 1508 *Heterozygote|Osteogenesis Imperfecta|Serpins|Eye Proteins|*Mutations|Nerve Growth Factors|Collagen Type I|Phenotype|Bone Density 130 SERPINF1 31059004 Int. J. Oncol. 2019 PMC6561627 10.3892/ijo.2019.4796 0 4 0 1508 Humans|*Histone Deacetylase Inhibitors|*Triple Negative Breast Neoplasms|*Genes, Tumor Suppressor|entinostat|Benzamides|Pyridines|Histone Deacetylases|Twist-Related Protein 1|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Cell Differentiation|Xenograft Model Antitumor Assays|Cell Proliferation|Angiogenesis Inhibitors|MCF7 Cells|Apoptosis|Genes, Regulator 130 SERPINF1 30968248 Mol. Genet. Genomics 2019 10.1007/s00438-019-01558-8 0 0 0 1508 Humans|*Otosclerosis|Serpins|Nerve Growth Factors|Eye Proteins|Osteogenesis Imperfecta|Heterozygote|DNA Mutational Analysis|Mutations|Bone Density|Exon|*Genes, Regulator|Stapes|Base Sequence 130 SERPINF1 30651300 Dis Model Mech 2019 PMC6361154 10.1242/dmm.035642 5 9 0 1508 Mice|Animals|*Retinal Degeneration|*Microphthalmos|Serpins|Eye Proteins|Nerve Growth Factors|Retinal Pigment Epithelium|Retina|Cells, Cultured 130 SERPINI1 31036010 BMC Med Genomics 2019 PMC6489260 10.1186/s12920-019-0502-y 1 0 0 165 Humans|*RNA, Long Noncoding|*mRNA|*Calcium Oxalate|RNA, Micro|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Transcriptome|Computational Biology 31 SERPINI1 30953370 J. Cell. Physiol. 2019 10.1002/jcp.28515 3 0 0 165 *Urinary Bladder Neoplasms|*Prognosis|DNA Methylation|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate|Bioinformatics|Gene Expression Regulation, Neoplastic|Proportional Hazards Models|Transcriptome|*Profiles, Genetic|ROC Curve|Messenger RNA|Multivariate Analysis 31 SERPINI1 30618144 J. Oral Pathol. Med. 2019 10.1111/jop.12824 1 2 0 165 *Squamous Cell Carcinoma|Oral Cancer|Azepines|Antineoplastic Agents|Proto-Oncogene Proteins c-myc|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Triazoles|Cell Proliferation|Xenograft Model Antitumor Assays|Apoptosis|Signal Transduction 31 SETBP1 31692115 J. Clin. Lab. Anal. 2019 PMC7031557 10.1002/jcla.23064 1 0 0 1118 Humans|*Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative|Leukemia, Neutrophilic, Chronic|Receptors, Colony-Stimulating Factor|*Sequencing, Next-Generation|*Mutations|*Receptors, Granulocyte Colony-Stimulating Factor|*Signal Transduction|Nuclear Proteins|Carrier Proteins|CSF3R protein, human 173 SETBP1 31681433 Front Genet 2019 PMC6813924 10.3389/fgene.2019.01005 2 0 0 1118 Humans|Female|*Whole Exome Sequencing|*Exome|Hereditary Breast and Ovarian Cancer Syndrome|BRCA2 Protein|Germ-Line Mutation|Breast Cancer, Familial|Breast Cancer|Genetic Predisposition to Disease|Ovarian Neoplasms|High-Throughput Nucleotide Sequencing 173 SETBP1 31680123 Genet. Med. 2019 10.1038/s41436-019-0680-1 1 0 0 1118 Pena Shokeir syndrome, type 1|*Arthrogryposis|*Genomics|Pedigree|Mutation 173 SETBP1 31377458 Leuk. Res. 2019 10.1016/j.leukres.2019.106190 0 0 0 1118 Humans|*Leukemia, Myelomonocytic, Chronic|*Leukemia, Myelomonocytic, Juvenile|Mutation|SETBP1 protein, human|Nuclear Proteins|Prognosis|Cytogenetic Aberrations|Carrier Proteins|High-Throughput Nucleotide Sequencing|Biomarkers, Tumor|Transcription Factors|Bone Marrow 173 SETBP1 31350176 Immunity 2019 PMC6703945 10.1016/j.immuni.2019.06.015 1 4 0 1118 Humans|Mice|Animals|*Methyltransferase, Histone|*Uric Acid|*Macrophage|*Phenotype|Histone-Lysine N-Methyltransferase|Inflammation|Histone|Wound Healing|Diabetes Mellitus, Type 2|Epigenesis, Genetic|Mice, Inbred C57BL|Cytokines 173 SETD5 31656537 Exp Ther Med 2019 PMC6812316 10.3892/etm.2019.8059 0 0 0 181 Child|Humans|Female|Infant|Intellectual Disability|Exome|Phenotype|Chromosome Deletion|Developmental Disabilities|Mutation|Sequencing, Whole Exome|Methyltransferases 41 SETD5 31515109 Neuron 2019 10.1016/j.neuron.2019.07.013 4 1 0 181 Humans|Animals|Mice|*Chromatin|*Methylation|*Neurons|Transcription, Genetic|Methyltransferases|Haploinsufficiency|Neural Stem Cells|Intellectual Disability|Mutations|Autism Spectrum Disorder|Brain|SETD5 protein, human 41 SETD5 31474762 Genet. Med. 2019 10.1038/s41436-019-0639-2 0 0 0 181 Child|Humans|*Moyamoya Disease|Whole Exome Sequencing|Exome|Intellectual Disability|Developmental Disabilities|Mutation|CNOT3 protein, human|Transcription Factors|CHD4 protein, human|Mi-2 Nucleosome Remodeling and Deacetylase Complex|SETD5 protein, human|Methyltransferases 41 SETD5 31345185 BMC Cancer 2019 PMC6659235 10.1186/s12885-019-5944-2 1 1 0 181 Humans|Male|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*PR-SET Domains|Neoplasm Invasiveness|A549 Cells|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|MicroRNAs|RNA Interference|Down-Regulation|Lymphatic Metastasis|Cell Line, Tumor|MAP Kinase Signaling System|*Neoplastic Processes|Prognosis|SETD5 protein, human|Methyltransferases 41 SETD5 31337854 J. Hum. Genet. 2019 10.1038/s10038-019-0643-z 0 6 0 181 Humans|*De Lange Syndrome|DNA Copy Number Variations|*Genetic Testing|Chromosomal Proteins, Non-Histone|Phenotype|Exome|Cell Cycle Proteins|Heterozygote|Genetic Association Studies|HDAC8 protein, human|Repressor Proteins|Mutation|Chondroitin Sulfate Proteoglycans|Sequencing, Whole Exome|KMT2A protein, human|Myeloid-Lymphoid Leukemia Protein|Genes, cdc|Histone-Lysine N-Methyltransferase 41 SETD5 30984543 FEBS Open Bio 2019 PMC6443872 10.1002/2211-5463.12600 2 0 0 181 *Histone-Lysine Methyltransferase|*Urinary Bladder Neoplasms|KMT2D protein, human|*Neoplasm Proteins|*DNA-Binding Proteins|*Mutations|Cell Line, Tumor|DNA Copy Number Variations 41 SETD5 30886212 Transl Psychiatry 2019 PMC6423133 10.1038/s41398-019-0454-1 1 2 0 181 Adult|Humans|*Genome-Wide Association Study|SNPs|Brain|Thinking|Psychiatric Disorders|Dorsolateral Prefrontal Cortex|Phenotypes|MicroRNAs|United Kingdom|Hungary|KCTD12 protein, human|Proteins|TPH2 protein, human|Tryptophan Hydroxylase|ATXN7L3B protein, human|Transcription Factors|MIRN383 microRNA, human 41 SETD5 30655503 Transl Psychiatry 2019 PMC6336863 10.1038/s41398-018-0344-y 4 1 0 181 Animals|Mice|*Haploinsufficiency|*Autistic Disorder|Autism Spectrum Disorder|Mice, Knockout|*Neurons|Behavior, Animal|Social Behavior|Intellectual Disability|Heterozygote|Methyltransferase, Histone|Disease Models, Animal 41 SETD5 30616239 Med. Sci. Monit. 2019 PMC6330996 10.12659/MSM.912294 3 1 0 181 Humans|Male|Set2 protein, human|Methyltransferase, Histone|Histone|*Prostate Cancer|Protein Methyltransferases|Polycomb Repressive Complex 2|DNA-Binding Proteins|Nuclear Proteins|Enhancer of Zeste Homolog 2 Protein|Lysine|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Carrier Proteins|SETD6 protein, human|Prdm12 protein, human|Nerve Tissue Proteins 41 SETMAR 31702817 Mol Med Rep 2019 PMC6854553 10.3892/mmr.2019.10777 0 1 0 173 *Transposases|*Dichlorodiphenyl Dichloroethylene|p31 integrase protein, Human immunodeficiency virus 1|*HIV Integrase|VDJ Recombinases|HIV Integrase Inhibitors|DNA Nucleotidyltransferases|*Retroviruses|Homeodomain Proteins|Binding Sites|Protein Binding|Recombinase|Catalytic Domain|RNase H|Recombination, Genetic 44 SETMAR 31238295 DNA Repair (Amst.) 2019 PMC6715855 10.1016/j.dnarep.2019.06.006 1 0 0 173 Animals|Humans|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|*DNA End-Joining Repair|mariner transposases|Transposases|DNA Repair|DNA-Binding Proteins|DNA Breaks, Double-Stranded|Histones|DNA|Recombination, Genetic 44 SETMAR 30764754 BMC Genet. 2019 PMC6375154 10.1186/s12863-019-0719-y 1 1 0 173 Humans|*DNA Transposable Elements|*Epigenesis, Genetic|DNA Methylation|Amino Acid Sequence|Gene Expression|Genome, Human 44 SEZ6L 31711114 Cereb. Cortex 2019 10.1093/cercor/bhz230 0 0 0 15 Animals|Mice|*Memory, Short-Term|*Dendritic Spines|Hippocampus|Mice, Knockout|Neurons|Brain|Maze Learning|Nerve Tissue Proteins|Functions, Cognitive|Sez6 protein, mouse 21 SEZ6L 30747226 Oncol. Rep. 2019 PMC6365694 10.3892/or.2019.6979 0 0 0 15 Humans|*Adenocarcinoma|Pancreatic Carcinoma|*Pancreatic Cancer|*Prognosis|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Computational Biology|Databases, Genetic|Kaplan-Meier Estimate|Transcriptome|Protein Interaction Maps|TINAG protein, human|Cell Adhesion Molecules 21 SFMBT2 31681586 Front Oncol 2019 PMC6813191 10.3389/fonc.2019.01048 1 0 0 127 Adult|Humans|Child|*Long Non-Coding RNA|Myelodysplastic Syndromes|*Myeloproliferative Disorders|Leukemia, Myeloid, Acute|Prognosis|Azacytidine|Bone Marrow|Cytogenetic Abnormalities|Hematopoietic Stem Cell Transplantation 46 SFMBT2 31556152 J. Clin. Lab. Anal. 2019 PMC6977404 10.1002/jcla.23049 4 0 0 127 *RNA, Circular|*Cancers|*Pathology, Molecular|MicroRNAs|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Transcriptomes 46 SFMBT2 31391163 Biol Open 2019 PMC6737984 10.1242/bio.043638 1 0 0 127 *Chromatin|*Trophoblasts|*Polycomb-Group Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Promoter Regions, Genetic 46 SFMBT2 30713549 Front Genet 2019 PMC6346411 10.3389/fgene.2018.00706 10 4 0 127 Pregnancy|Female|Animals|Genomic Imprinting|*Placenta|*Mammals|DNA Methylation|Epigenesis, Genetic|Transcription Factors|MicroRNAs|Intron|Multigene Family 46 SFRP5 31849123 Phytother Res 2019 10.1002/ptr.6568 0 0 0 234 Humans|nicotinamide phosphoribosyltransferase, human|*Nicotinamide Phosphoribosyltransferase|*Glycemic Index|*L-Carnitine|*Double-Blind Method|*Pemphigus|ITLN1 protein, human|*Cytokines|*Lectins|Insulin Resistance|Insulin|Blood Glucose|*GPI-Linked Proteins|Dietary Supplements|Body Mass Index|SFRP5 protein, human|Eye Proteins|Membrane Proteins 269 SFRP5 31770545 Metab. Clin. Exp. 2019 10.1016/j.metabol.2019.154029 0 10 0 234 Animals|Mice|*Glucose|very low density lipoprotein triglyceride|*Lipoproteins, VLDL|*Triglycerides|*Liver|Insulin Resistance|Lipid Metabolism|Insulin|Diet, High-Fat|Obesity|Blood Glucose|Homeostasis|Sfrp5 protein, mouse|Intercellular Signaling Peptides and Proteins 269 SFRP5 31754130 Sci Rep 2019 PMC6872918 10.1038/s41598-019-53509-3 1 4 0 234 Humans|Female|*Curcumin|Epigenesis, Genetic|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Wnt Signaling Pathway|DNA Methylation|Epithelial-Mesenchymal Transition|*Carcinogenesis|beta Catenin|*Catenins|Azacitidine|Membrane Proteins|DNA Modification Methylases|Promoter Regions, Genetic|Cell Line, Tumor|Eye Proteins|Cell Proliferation 269 SFRP5 31597481 Connect. Tissue Res. 2019 10.1080/03008207.2019.1665034 1 2 0 234 269 SFRP5 31534019 Sci Transl Med 2019 PMC7212031 10.1126/scitranslmed.aav5055 2 1 0 234 Humans|*Oxidases, NADPH|WNT5A protein, human|*Wnt-5a Protein|*Obesity|*Adipose Tissue|FZD2 protein, human|Frizzled Receptors|Wnt Proteins|Wnt Signaling Pathway|Membrane Proteins|Eye Proteins|Diabetes Mellitus, Type 2|*Redox|Myocytes, Smooth Muscle|RAC1 protein, human|rac1 GTP-Binding Protein 269 SFRP5 31516566 Oncol Lett 2019 PMC6733008 10.3892/ol.2019.10709 3 3 0 234 Humans|*DNA Methylation|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Membrane Proteins|*Promoter Regions, Genetic|SFRP4 protein, human|Proto-Oncogene Proteins|Hepatocellular Carcinoma|Eye Proteins|Colorectal Cancer|Gene Silencing|Gene Expression Regulation, Neoplastic|Wnt Pathway|Cell Line, Tumor|Cell Transformation, Neoplastic|Liver Neoplasms 269 SFRP5 31470850 J. Biomed. Sci. 2019 PMC6717377 10.1186/s12929-019-0556-3 1 6 0 234 Mice|Female|Humans|Rats|Animals|*Raloxifene Hydrochloride|*3T3-L1 Cells|*Adipogenesis|Selective Estrogen Receptor Modulators|*Adipose Tissue|Ovariectomy|*Inflammation|Estrogen Replacement|Estradiol|Obesity|Menopause 269 SFRP5 31199714 J. Interferon Cytokine Res. 2019 PMC6660834 10.1089/jir.2018.0154 0 1 0 234 *Wnt Signaling Pathway|*Cardiovascular Diseases|Adipokines|Adipose Tissue|*Atherosclerosis|Insulin Resistance|Eye Proteins|Membrane Proteins|Obesity 269 SFRP5 31170681 Nutrition 2019 10.1016/j.nut.2019.03.009 0 0 0 234 Humans|Female|*Metabolic Syndrome|*Cinnamomum zeylanicum|*Endurance Training|*Wnt Signaling Pathway|WNT5A protein, human|Wnt-5a Protein|Insulin Resistance|Wnt Proteins|Eye Proteins|Proto-Oncogene Proteins|Diabetes Mellitus, Type 2|Membrane Proteins|Adipokines|Plant Extracts 269 SGCA 31836381 J Clin Neurosci 2019 10.1016/j.jocn.2019.12.003 0 0 0 379 Humans|*Sarcoglycanopathies|Sarcoglycans|Limb-girdle muscular dystrophy autosomal recessive|Muscular Dystrophies, Limb Girdle|Mutation|Phenotype|Homozygote|Muscle, Skeletal|Immunohistochemistry|Biopsy 116 SGCA 31586292 Med Health Care Philos 2019 10.1007/s11019-019-09927-1 0 0 0 379 Child|Humans|Prospective Studies|*Wrongful Births|Negligence|Compensation|Genetic Counseling|Singapore 116 SGCA 31430305 PLoS ONE 2019 PMC6701749 10.1371/journal.pone.0220665 3 0 0 379 Male|Mice|Animals|*Cross-Sectional Studies|*Muscular Dystrophies, Limb-Girdle|LGMD2D|Sarcoglycans|Skeletal Muscles|Phenotype|Mutations|Cardiomyopathy 116 SGCA 31066050 Ann. Hum. Genet. 2019 10.1111/ahg.12319 0 0 0 379 *Muscular Dystrophies, Limb Girdle|*Sequencing, Next-Generation|Sequence Analysis, DNA|Mutation 116 SGCA 30989758 Neuropathology 2019 PMC6850699 10.1111/neup.12549 0 1 0 379 Humans|*Sarcoglycans|*Mutation, Missense|Sarcoglycanopathy|Muscular Dystrophies, Limb-Girdle|Exons|Mutations|Phenotype|Muscle, Skeletal 116 SGCA 30919934 Clin. Genet. 2019 10.1111/cge.13544 0 0 0 379 Humans|Retrospective Studies|Netherlands|Limb-girdle muscular dystrophy autosomal recessive|Limb Girdle Muscular Dystrophy|Muscular Dystrophy, Limb-Girdle, Type 2L|Limb-girdle muscular dystrophy type 2H|Muscular Dystrophy, Limb-Girdle, Type 2I|Limb-girdle muscular dystrophy, type 2B|Limb-girdle muscular dystrophy type 2A|*Muscular Dystrophies|Dysferlin|Muscle Proteins|Calpain|Mutations|Membrane Proteins|Limb-girdle muscular dystrophy, type 2C|Sarcoglycanopathy|DYSF protein, human 116 SGCA 30838895 Hum. Gene Ther. 2019 PMC6648191 10.1089/hum.2019.006 3 0 0 379 *Sarcoglycanopathies|*Chemotherapy, Cancer, Regional Perfusion|*Gene Transfer Techniques|*Genetic Therapy|alpha Sarcoglycan|Dependovirus|Muscular Dystrophies, Limb-Girdle|Genetic Vectors|Muscle, Skeletal|Gene Expression 116 SGCA 30764848 Orphanet J Rare Dis 2019 PMC6376703 10.1186/s13023-019-1021-9 2 0 0 379 Humans|Limb-girdle muscular dystrophy type 2F|Limb-girdle muscular dystrophy, type 2C|Limb-girdle muscular dystrophy, type 2E|*Sarcoglycanopathies|Limb-girdle muscular dystrophy autosomal recessive|Muscular Dystrophies, Limb-Girdle|Sarcoglycans|Phenotype|Mutations|*Cohort Studies|*Chinese 116 SGCA 30703231 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.02.010 0 0 0 379 Humans|*Pedigree|*Sarcoglycanopathies|Muscular Dystrophies, Limb-Girdle|Exons|Muscular Dystrophy, Duchenne|Sequence Deletion|Sequencing, Whole Exome|Mutation|Chinese 116 SGCA 30621359 J Clin Med 2019 PMC6352223 10.3390/jcm8010050 5 0 0 379 Humans|*Diagnosis, Differential|Bayes Theorem|*Rheumatoid Arthritis|*Osteoarthritis|Synovial Membrane|Oligonucleotide Array Sequence Analysis|Transcriptome|*Genetic Markers|*Intelligence 116 SGCD 31689918 Int J Mol Sci 2019 PMC6862322 10.3390/ijms20215480 0 1 0 100 Mice|Animals|Humans|Aged|*Sarcoglycans|Mice, Knockout|Phenotype|Disease Models, Animal 88 SGCD 31430305 PLoS ONE 2019 PMC6701749 10.1371/journal.pone.0220665 3 0 0 100 Male|Mice|Animals|*Cross-Sectional Studies|*Muscular Dystrophies, Limb-Girdle|LGMD2D|Sarcoglycans|Skeletal Muscles|Phenotype|Mutations|Cardiomyopathy 88 SGCD 31179125 Cardiol Res Pract 2019 PMC6507268 10.1155/2019/2743650 0 1 0 100 Humans|*Cardiomyopathy, Dilated|*Implantable Cardioverter-Defibrillator|Stroke Volume|Ventricular Function, Left|Sudden Cardiac Death|*Sequencing, Next-Generation|Genetic Testing|Genetic Predisposition to Disease|Risk Factors 88 SGCD 31066050 Ann. Hum. Genet. 2019 10.1111/ahg.12319 0 0 0 100 *Muscular Dystrophies, Limb Girdle|*Sequencing, Next-Generation|Sequence Analysis, DNA|Mutation 88 SGCD 31024045 Mod. Pathol. 2019 10.1038/s41379-019-0274-0 0 0 0 100 Humans|Male|Female|Adolescent|Young Adult|Adult|Middle Aged|Aged|*Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathy|Cardiomyopathy, Dilated|Death, Sudden, Cardiac|Genetic Testing|Autopsy|Mutations|Sequencing, Next-Generation|Myocardium|Gene Frequency|Myocarditis|Arrythmia|Genetic Predisposition to Disease|Heart Ventricles 88 SGCD 30938105 Cancer Med 2019 PMC6536925 10.1002/cam4.1845 2 0 0 100 Humans|Male|*Gene Regulatory Networks|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|*Prostate Cancer|Gene Ontology|*Diabetes Mellitus, Type II|Gene Expression Profiling|Computational Biology|Signal Transduction|Apoptosis 88 SGCD 30933441 Cell. Physiol. Biochem. 2019 10.33594/000000054 0 0 0 100 Rats|Animals|*Proteomics|*Transcriptome|*Gastrocnemius Muscle|Muscle Denervation|*Electrical Stimulation|Muscle Fibers, Skeletal|Electric Stimulation Therapy 88 SGCD 30919934 Clin. Genet. 2019 10.1111/cge.13544 0 0 0 100 Humans|Retrospective Studies|Netherlands|Limb-girdle muscular dystrophy autosomal recessive|Limb Girdle Muscular Dystrophy|Muscular Dystrophy, Limb-Girdle, Type 2L|Limb-girdle muscular dystrophy type 2H|Muscular Dystrophy, Limb-Girdle, Type 2I|Limb-girdle muscular dystrophy, type 2B|Limb-girdle muscular dystrophy type 2A|*Muscular Dystrophies|Dysferlin|Muscle Proteins|Calpain|Mutations|Membrane Proteins|Limb-girdle muscular dystrophy, type 2C|Sarcoglycanopathy|DYSF protein, human 88 SGCD 30782477 Neuromuscul. Disord. 2019 10.1016/j.nmd.2018.12.006 2 0 0 100 Humans|Mice|Animals|*Dystrophin|*Adeno-Associated Virus|*mdx Mice|*Sarcoglycans|*Heart|Cardiomyopathy|*Gene Therapy|Muscular Dystrophies|Left Ventricular Function|Myocardium|Heart Failure|Gene Transfer Techniques|Disease Models, Animal|SGCD protein, human 88 SGCD 30764848 Orphanet J Rare Dis 2019 PMC6376703 10.1186/s13023-019-1021-9 2 0 0 100 Humans|Limb-girdle muscular dystrophy type 2F|Limb-girdle muscular dystrophy, type 2C|Limb-girdle muscular dystrophy, type 2E|*Sarcoglycanopathies|Limb-girdle muscular dystrophy autosomal recessive|Muscular Dystrophies, Limb-Girdle|Sarcoglycans|Phenotype|Mutations|*Cohort Studies|*Chinese 88 SGCD 30733730 Front Genet 2019 PMC6354032 10.3389/fgene.2018.00727 1 1 0 100 88 SH3PXD2B 31809395 J. Glaucoma 2019 10.1097/IJG.0000000000001420 0 0 0 105 Humans|Child|Ter Haar syndrome|*Siblings|*Craniofacial Abnormalities|*Osteochondrodysplasias|*Heart Defects, Congenital|*Developmental Disabilities|*Hydrophthalmos|Megalocornea|Genetic Diseases, X-Linked|Abnormalities, Multiple|Eye Diseases, Hereditary|Brachycephaly|*Optic Nerve Diseases|Mutation|*Retinal Degeneration 23 SH3PXD2B 31218820 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61264 2 0 0 105 Humans|Child|Animals|*Osteolysis, Multicentric|Ter Haar syndrome|Craniofacial Abnormalities|Homozygote|Winchester syndrome|Abnormalities, Multiple|Mutation|Osteochondrodysplasias|MMP14 protein, human|Metalloproteinase 14, Matrix|Osteolysis|Heart Defects, Congenital|Phenotype|Growth Disorders|Corneal Opacity|Amino Acid Sequence|Osteoporosis|Contracture 23 SH3PXD2B 31211954 Exp. Eye Res. 2019 10.1016/j.exer.2019.107703 1 0 0 105 Humans|Mice|Animals|Early-Onset Glaucoma|*Retinal Ganglion Cells|Neurodegenerative Diseases|*Mice, Inbred C57BL|*Glaucoma|*Ocular Hypertension|Optic Nerve Diseases|Intraocular Pressure|Tonometry, Ocular|Optic Nerve Head|*Disease Models, Animal|Retinal Degeneration|Axons 23 SH3PXD2B 30962481 Sci Rep 2019 PMC6453952 10.1038/s41598-019-42250-6 2 0 0 105 Humans|Child|Mice|Animals|Ter Haar syndrome|Craniofacial Abnormalities|Osteochondrodysplasias|Heart Defects, Congenital|Adaptor Proteins, Signal Transducing|*Bone Tissue|Homozygote|Developmental Disabilities|Mutations|Osteogenesis|*Homeostasis|Phenotypes|Bone Marrow Stromal Stem Cells|Osteoporosis|Tks4 protein, human|Tks4 protein, mouse|Phosphoproteins 23 SHOX 31834863 J. Pediatr. Endocrinol. Metab. 2019 10.1515/jpem-2019-0234 0 0 0 122 Child|Humans|*Dwarfism|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|Short Stature Homeobox Protein|IGF1 protein, human|Insulin-Like Growth Factor I|Human Growth Hormone|Growth Disorders|Genotype-Phenotype Correlation|Heterozygote|Frameshift Mutation|Exon|Carrier Proteins|Homeodomain Proteins|SHOX protein, human 412 SHOX 31810463 BMC Genomics 2019 PMC6898931 10.1186/s12864-019-6270-4 0 0 0 122 Animals|Cattle|*Genome-Wide Association Study|Australia|Quantitative Trait Loci|Phenotype|Genotype|Animal Feed|Single Nucleotide Polymorphisms|Eating|*Gene Expression|Body Weight 412 SHOX 31781162 Front Genet 2019 PMC6852097 10.3389/fgene.2019.01086 0 0 0 122 Short Stature Homeobox Protein|*Heterozygote|Osteochondrodysplasias|Homeodomain Proteins|Dwarfism|Sequence Deletion|Growth Disorders|Transcription Factors|Pedigree 412 SHOX 31751304 Eur. J. Endocrinol. 2019 10.1530/EJE-19-0785 0 0 0 122 Humans|Short Stature Homeobox Protein|Growth Disorders|Osteochondrodysplasias|*Body Weights and Measures 412 SHOX 31731040 Eur J Med Genet 2019 10.1016/j.ejmg.2019.103812 0 0 0 122 Humans|Female|46, XX Disorders of Sex Development|Mullerian Ducts|*Abnormalities, Multiple|Vagina|Uterus|Esophagus|Kidneys|*Chromosome Structures|PAX8 protein, human|PAX8 Transcription Factor|SHOX protein, human|Short Stature Homeobox Protein|IL36RN protein, human|Interleukins 412 SHOX 31467065 Arch Dis Child Educ Pract Ed 2019 10.1136/archdischild-2019-317564 0 0 0 122 Male|Humans|Child|Short Stature Homeobox Protein|Growth Disorders|Osteochondrodysplasias|Homeodomain Proteins|*Dwarfism|Value, Normal|Wrists 412 SHOX 31412912 Ital J Pediatr 2019 PMC6692937 10.1186/s13052-019-0694-y 0 1 0 122 Child|Humans|Female|Child, Preschool|*Haploinsufficiency|In Situ Hybridization, Fluorescence|Comparative Genomic Hybridization|Short Stature Homeobox Protein|*Human Growth Hormone|Leri-Weil syndrome|Growth Disorders|Osteochondrodysplasias|Karyotyping|Growth Hormone|Homeodomain Proteins|Y Chromosome|Gene Deletion|Karyotype|Translocation, Genetic|X Chromosome|SHOX protein, human 412 SHOX 31406617 J Pediatr Genet 2019 PMC6688879 10.1055/s-0039-1691788 1 0 0 122 Child|Humans|Infant, Newborn|Infant|Child, Preschool|Adolescent|Cohort Studies|*Follow-Up Studies|Short Stature Homeobox Protein|Growth Disorders|Osteochondrodysplasias|Homeodomain Proteins|Phenotype|Mutation|*Rare Diseases|SHOX protein, human 412 SHOX 31228230 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61275 0 0 0 122 Humans|Leri-Weil syndrome|*Osteochondrodysplasias|*Growth Disorders|Short Stature Homeobox Protein|Dwarfism|*DNA Copy Number Variations|Homeodomain Proteins|Pedigree|Frequencies, Allele|Sequence Deletion|Mutations|*Sisters|Haploinsufficiency|Haplotype|Genotypes|Cohort Studies|*Nucleotides|SHOX protein, human 412 SHOX2 31839603 Cancer Biomark 2019 10.3233/CBM-190258 0 0 0 519 Humans|*Carcinoma, Non-Small-Cell Lung|*Pemetrexed|*Lung Cancer|DNA Methylation|Tumor Suppressor Proteins|Prognosis|Promoter Regions, Genetic|*Disease Progression|Disease-Free Survival|Biomarkers, Tumor|gemcitabine|Deoxycytidine 184 SHOX2 31829064 J. Recept. Signal Transduct. Res. 2019 10.1080/10799893.2019.1701031 1 4 0 519 184 SHOX2 31817025 J Clin Med 2019 PMC6947244 10.3390/jcm8122134 0 1 0 519 Humans|*Nonsmall Cell Lung Cancer|*Prognosis|Lung Neoplasms|Neoplasm Recurrence, Local|*Liquid Biopsy|TNM Staging System|DNA Methylation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Serine Endopeptidases|Promoter Regions, Genetic|Membrane Proteins|TMPRSS4 protein, human 184 SHOX2 31678351 J. Mol. Cell. Cardiol. 2019 PMC7035977 10.1016/j.yjmcc.2019.09.015 0 1 0 519 Humans|Mice|Animals|*Sinoatrial Node|HCN2 Channel|Myocytes, Cardiac|Sick Sinus Syndrome|Cell Differentiation|Potassium Channels|Biological Clocks|*Pacemaker, Artificial|*Multipotent Stem Cells|Heart Failure|Transcription Factors|SHOX2 protein, human|Homeodomain Proteins|KCNN4 protein, human|Intermediate-Conductance Calcium-Activated Potassium Channels|Tbx18 protein, mouse|T-Box Domain Proteins|Kcnn4 protein, mouse 184 SHOX2 31649510 Front Cell Neurosci 2019 PMC6794418 10.3389/fncel.2019.00452 0 0 0 519 Mice|Animals|Cats|Rats|*Ankle|*Animals, Newborn|Locomotion|Interneurons|Spinal Cord|Motor Neurons|Hindlimb|Afferent Pathways|Neurons, Afferent|*Ankle Joint|Roots, Dorsal|Electric Stimulation|Proprioceptions|Muscles|*Nervous System Physiological Phenomena|Shox2 protein, rat|Homeodomain Proteins 184 SHOX2 31649032 J. Biol. Chem. 2019 PMC6885637 10.1074/jbc.RA119.008801 1 0 0 519 Mice|Animals|*Osteogenesis|*Palate, Hard|*Cell Differentiation|Cell Lineage|Mesoderm|Homeodomain Proteins|Gene Expression Regulation, Developmental|Signal Transduction|Cleft Palate 184 SHOX2 31648393 Stem Cells 2019 10.1002/stem.3106 1 1 0 519 Chick Embryo|Mice|Humans|Animals|*Myocytes, Cardiac|*Human Embryonic Stem Cells|*Wnt Signaling Pathway|Human Induced Pluripotent Stem Cells|Embryonic Stem Cells|Cell Differentiation|*Mesoderm|Sinoatrial Node|Wnt Proteins|beta Catenin|Potential, Action|Pacemaker, Artificial|SHOX2 protein, human|Homeodomain Proteins|Tbx18 protein, mouse|T-Box Domain Proteins 184 SHOX2 31638180 Int. J. Mol. Med. 2019 PMC6844603 10.3892/ijmm.2019.4374 0 0 0 519 Rats|Mice|Animals|*Potassium Channel|*Pacemakers, Biological|*Stem Cells|Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels|Cardiomyocytes|Cell Differentiation|Sinoatrial Node|T-Box Domain Proteins|Gene Expression Regulation|Shox2 protein, rat|Homeodomain Proteins 184 SHOX2 31633376 DNA Cell Biol. 2019 10.1089/dna.2019.4940 0 0 0 519 Sinoatrial Node|Induced Pluripotent Stem Cells|T-Box Domain Proteins|Cell Differentiation|Myocytes, Cardiac|Cells, Cultured|3'-(1-butylphosphoryl)adenosine|*Complement Factor B 184 SHOX2 31581653 Int J Mol Sci 2019 PMC6801533 10.3390/ijms20194890 0 0 0 519 Humans|*Saphenous Vein|*Mammary Arteries|Coronary Artery Bypass Grafting|Vascular Patency|Coronary Artery Disease|Graft Occlusion, Vascular|Coronary Angiography|*Femoral Vein|*Biomarkers|*Bone Development 184 SHROOM2 30683844 Cell Death Dis 2019 PMC6347642 10.1038/s41419-019-1325-7 4 3 0 47 Mice|Animals|*Nasopharyngeal Carcinoma|RHOA protein, human|*rhoA GTP-Binding Protein|Epithelial-Mesenchymal Transition|Cell Migration|Nasopharyngeal Neoplasms|Signal Transduction|Neoplasm Invasiveness|Proto-Oncogene Proteins c-akt|Carcinoma|Cell Line, Tumor|Mice, Nude|Downregulation 26 SIDT2 31061008 J. Immunol. 2019 10.4049/jimmunol.1801369 0 2 0 73 *RNA, Double-Stranded|*Lysosomes|*Endosomes|Encephalomyocarditis virus|Cardiovirus Infections|RNA Transport|Nucleotide Transport Proteins|Innate Immune Response|Membrane Proteins|Protein Binding|*RNA, Double-Stranded|*Lysosomes|*Endosomes|Encephalomyocarditis virus|Cardiovirus Infections|RNA Transport|Nucleotide Transport Proteins|Innate Immune Response|Membrane Proteins|Protein Binding 25 SIDT2 31546103 iScience 2019 PMC6817685 10.1016/j.isci.2019.09.009 0 25 0 73 *RNA Transport|Lysosomes|Membrane Proteins|Endosomes|Nucleotide Transport Proteins|Autophagy|Double-Stranded RNA|*Gastrointestinal Neoplasms 25 Sigmar1 31695608 Front Pharmacol 2019 PMC6816035 10.3389/fphar.2019.01141 0 0 0 1064 *Cancer|Receptors, sigma|Ligands 92 Sigmar1 31511340 J. Med. Genet. 2019 PMC7042970 10.1136/jmedgenet-2019-106108 0 1 0 1064 Humans|*Hereditary Motor Neuronopathy|Pedigree|Mutations|Phenotype|Receptors, sigma|Jordan 92 Sigmar1 31475037 Front Genet 2019 PMC6707335 10.3389/fgene.2019.00732 2 0 0 1064 Humans|*Amyotrophic Lateral Sclerosis|Neurodegenerative Diseases|Hungary|C9orf72 Protein|*Genetic Testing|Superoxide Dismutase-1|Genetic Association Studies|Genetic Predisposition to Disease|*Cohort Studies|Genetic Variation|High-Throughput Nucleotide Sequencing|Mutation 92 Sigmar1 31167812 J. Neurol. Neurosurg. Psychiatry 2019 10.1136/jnnp-2019-320717 2 0 0 1064 Humans|Inherited Peripheral Neuropathy|Hereditary Neuropathy, Charcot-Marie-Tooth|Mutations|Pedigree|HSP27 Heat-Shock Proteins 92 Sigmar1 31096213 Neuropsychobiology 2019 10.1159/000497164 0 0 0 1064 *Alzheimer Disease|Genetic Predisposition to Disease|Catechol O-Methyltransferase|Genetic Association Studies|Polymorphism, Single Nucleotide|*Comorbidity|Gene Frequency|Genotype|Case-Control Studies|*Neurotransmission 92 Sigmar1 30990365 Autophagy 2019 PMC6984592 10.1080/15548627.2019.1607686 4 0 0 1064 Mice|Animals|*Mitophagy|*Cocaine|BECN1 protein, human|Beclin-1|Mitochondria|Autophagosome|Autophagy|*Superoxide Dismutase|Reactive Oxygen Species|Microglia|Signal Transduction|*Macrophage Activation|Cytokines|Upregulation|Optn protein, mouse|Eye Proteins 92 Sigmar1 30871407 Autophagy 2019 PMC6693456 10.1080/15548627.2019.1586248 2 3 0 1064 *Autophagosomes|sigma-1 receptor|*Receptors, sigma|Mitophagy|Autophagy|Lysosomes|Mitochondria|Carbonyl Cyanide m-Chlorophenyl Hydrazone|Membrane Fusion|Endoplasmic Reticulum 92 Sigmar1 30661753 Cell 2019 PMC6440749 10.1016/j.cell.2018.12.012 5 2 0 1064 Humans|Mice|Animals|*Astrocytes|XBP1 protein, human|X-Box Binding Protein 1|Experimental Autoimmune Encephalomyelitis|ERN1 protein, human|Endoribonucleases|*Inflammation|Protein-Serine-Threonine Kinases|Multiple Sclerosis|Signal Transduction|Central Nervous System|Mice, Inbred C57BL 92 SIM2 31783895 Breast Cancer Res. 2019 PMC6884910 10.1186/s13058-019-1224-y 0 10 0 147 Humans|Female|*Cyclooxygenase 2|*Nuclear Factor-Kappab|Basic Helix-Loop-Helix Transcription Factors|Transcriptional Activation|Signal Transduction|Cell Line, Tumor|Upregulation|Apoptosis|SIM2 protein, human 122 SIM2 31775907 Breast Cancer Res. 2019 PMC6882179 10.1186/s13058-019-1207-z 0 1 0 147 DNA Repair|Rad51 Recombinase|DNA Replication|DNA Breaks, Double-Stranded|Homologous Recombination|Genomic Instability|DNA Damage|DNA-Binding Proteins|Protein Binding|Cell Line, Tumor 122 SIM2 31340933 Development 2019 10.1242/dev.175042 1 2 0 147 Humans|*Genes, Homeobox|Homeodomain Proteins|Body Patterning|Facial Bones|Gene Expression Regulation, Developmental|Transcription Factors|Histone Acetyltransferases|Embryo, Mammalian|*Gene Expression|Mutation 122 SIM2 31305891 Carcinogenesis 2019 10.1093/carcin/bgz129 0 1 0 147 Humans|Male|*mRNA|*Prostate|kallikrein-related peptidase 3, human|Prostate Specific Antigen|Gleason Score|Prostatectomy|Prostate Cancer|Kallikreins|Biopsy|Seminal Vesicles|Biomarkers, Tumor|Specificity|GOLM1 protein, human|Membrane Proteins|SIM2 protein, human|Basic Helix-Loop-Helix Transcription Factors|OR51E2 protein, human|Neoplasm Proteins 122 SIM2 31074151 Orthod Craniofac Res 2019 10.1111/ocr.12260 1 0 0 147 Cell Differentiation|Osteogenesis|Adipogenesis|Chondrogenesis|Mesenchymal Stem Cells|Bone Marrow Cells|Osteoblasts|Adipocytes|Pluripotent Stem Cells|Cells, Cultured|Bone Marrow|Cartilage|*Biomarkers 122 SIM2 30940169 Virol. J. 2019 PMC6446281 10.1186/s12985-019-1134-8 0 4 0 147 *HIV Integrase|*Sumoylation|*Virus Replication|SUMO-1 Protein|UBB protein, human|*Ubiquitin|Virus Integration|HIV-1|PSIP1 protein, human|Transcription Factors|Protein Interaction Domains and Motifs|Protein Binding|lens epithelium-derived growth factor|Intercellular Signaling Peptides and Proteins|Adaptor Proteins, Signal Transducing 122 SIM2 30808286 BMC Genomics 2019 PMC6390542 10.1186/s12864-019-5530-7 0 3 0 147 Cattle|Animals|*Hamstring Muscles|Myogenesis|*Cell Differentiation|Satellite Cells, Skeletal Muscle|Gene Expression Profiling|*Gene Expression|Cells, Cultured|Breeding|*Paraspinal Muscles 122 SIX2 31806659 Development 2019 PMC6983716 10.1242/dev.177022 1 7 0 330 Humans|*Erythropoiesis|1,2-cyclohexanediamine|Homeodomain Proteins|Paired Box Transcription Factors|Nuclear Proteins|Intracellular Signaling Peptides and Proteins|Protein Tyrosine Phosphatases|Gene Expression Regulation, Developmental|Transcriptional Networks 281 SIX2 31765609 Dev. Biol. 2019 10.1016/j.ydbio.2019.11.010 0 2 0 330 Humans|*Osteogenesis|PAX1 transcription factor|*Paired Box Transcription Factors|Palate|Cleft Palate|Morphogenesis|Gene Expression Regulation, Developmental|Signal Transduction|SIX2 protein, human|Nerve Tissue Proteins|Homeodomain Proteins|PAX9 protein, human|PAX9 Transcription Factor 281 SIX2 31720997 J. Mol. Neurosci. 2019 10.1007/s12031-019-01416-7 0 9 0 330 AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Neuroblastoma|6 Hydroxydopamine|*Signal Transduction|Glial Cell Line-Derived Neurotrophic Factor|Dopaminergic Neurons|Transcription Factor|Neuroprotective Agents|Gene Expression Regulation|*B Cells|Parkinson Disease|Cell Survival|Neurotoxins|Cell Death|Neuroglia 281 SIX2 31651345 J Hematol Oncol 2019 PMC6814126 10.1186/s13045-019-0809-3 0 0 0 330 Humans|*Pseudogenes|*Transcription Factor|MCF-7 Cells|Cytochrome P450 Family 4|Cell Line, Tumor|3' Untranslated Regions|Gene Expression Regulation, Neoplastic|RNA, Messenger|SIX2 protein, human|Nerve Tissue Proteins|Homeodomain Proteins|CYP4Z1 protein, human 281 SIX2 31575031 Int J Mol Sci 2019 PMC6801716 10.3390/ijms20194867 0 0 0 330 Humans|*Embryoid Bodies|Carcinoma, Renal Cell|Kidney Neoplasms|Proto-Oncogene Proteins c-met|Carcinoma, Papillary|Oncogenes|Mutation|*Induced Pluripotent Stem Cells 281 SIX2 31564506 HBPD INT 2019 10.1016/j.hbpd.2019.09.005 0 2 0 330 *Carcinoma, Hepatocellular|*Epithelial-Mesenchymal Transition|*Liver Neoplasms|*Signal Pathway|*Prognosis|Snail Family Transcription Factors|Cell Movement|Gene Expression Regulation, Neoplastic|Hep G2 Cells|Up-Regulation|Cell Proliferation|Cell Line, Tumor|Tumorigenesis|Kaplan-Meier Estimate 281 SKA3 31804459 Cell Death Dis 2019 PMC6895034 10.1038/s41419-019-2163-3 1 3 0 193 Humans|*Carcinoma, Hepatocellular|*Tumor Suppressor Protein p53|*Phosphorylation|*Liver Neoplasms|Cell Proliferation|CDK2 protein, human|*Cyclin-Dependent Kinase 2|*Genes, cdc|Apoptosis|Signal Transduction|Downregulation|Kinetochore|Cell Cycle|Hep G2 Cells|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Mitosis 37 SKA3 31804178 Elife 2019 PMC6927755 10.7554/eLife.49539 4 2 0 193 *Microtubule|Kinetochores|NDC80 protein, human|*Nuclear Proteins|Chromosome Segregation|Spindle Apparatus|Microtubule-Associated Proteins|Cytoskeletal Proteins|Aurora Kinase B|Phosphorylation|Protein Binding 37 SKA3 30906829 Genes Dis 2019 PMC6411626 10.1016/j.gendis.2018.11.001 0 25 0 193 Kinetochores|Chromosomal Proteins, Non-Histone|*Cell Transformation, Neoplastic|*Tumorigenesis|*Genes, cdc|Mitosis|*Cell Cycle|*Psychiatric Disorders|Cell Line, Tumor|Gene Expression Regulation|DNA Methylation|Suicidal Ideation 37 SKOR1 31706190 Sleep Med. 2019 10.1016/j.sleep.2019.07.003 1 0 0 30 *Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Genetic Susceptibility|PTPRD protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Homeodomain Proteins|Genes, Homeobox|Genome-Wide Association Study|Transcription Factors|Polymorphism, Single Nucleotide|*Pain|Nerve Tissue Proteins|Case-Control Studies|High Mobility Group Proteins 24 SKOR1 31526458 Zhongguo Fei Ai Za Zhi 2019 PMC6754573 10.3779/j.issn.1009-3419.2019.09.01 0 0 0 30 *DNA Methylation|*Genes, Suppressor|*Lung Cancer|*Regulatory Regions|Carcinoma, Non-Small-Cell Lung|*PCR|Tumor Suppressor Proteins|Promoter Regions, Genetic|DNA, Neoplasm 24 SKOR1 30760885 Eur. J. Hum. Genet. 2019 PMC6777609 10.1038/s41431-019-0355-z 0 0 0 30 Pregnancy|Female|Humans|Genome-Wide Association Study|United Kingdom|*Biological Specimen Banks|Twins, Dizygotic|*Multiple Births|Twins, Monozygotic|*Pregnancy, Multiple|Mothers|Phenotype 24 SLC16A12 31348313 Medicine (Baltimore) 2019 PMC6708703 10.1097/MD.0000000000016624 0 0 0 24 Humans|*Carcinoma, Renal Cell|*mRNA|Kidney Neoplasms|Prognosis|Neoplasm Staging|Kaplan-Meier Analysis|Biomarkers, Tumor|Disease-Free Survival|Gene Expression Regulation, Neoplastic|Kidney 24 SLC16A12 31213476 Cancer Prev Res (Phila) 2019 10.1158/1940-6207.CAPR-19-0035 1 0 0 24 Male|Genome-Wide Association Study|*Prostate|Helicobacter Infections|Helicobacter pylori|Gastric Cancer|SNPs|Gastric Mucosa|Genetic Predisposition to Disease|Antigens, Neoplasm|Neoplasm Proteins|GPI-Linked Proteins|DNA Methylation|Stem Cells 24 SLC16A12 30704470 BMC Med Genomics 2019 PMC6357449 10.1186/s12920-018-0467-2 2 0 0 24 Humans|*Glucocorticoids|*Transcriptome|NR3C1 protein, human|Glucocorticoid Receptor|*Cells, Epithelial|*Cell Lines|Adrenergic beta-2 Receptor Agonists|Asthma|Bronchi|Respiratory Mucosa|Transcription, Genetic|Corticosteroids 24 SLC16A4 31795962 BMC Cancer 2019 PMC6889185 10.1186/s12885-019-6353-2 1 2 0 345 *Neoadjuvant Therapy|Carbonic Anhydrase IX|Carbonic Anhydrases|Antigens, Neoplasm|Monocarboxylic Acid Transporters|Disease-Free Survival|Biomarkers, Tumor|Muscle Proteins 271 SLC16A4 31719150 J. Biol. Chem. 2019 PMC6937558 10.1074/jbc.RA119.009093 5 2 0 345 *Lactate|SLC16A3 protein, human|*Monocarboxylic Acid Transporters|SLC16A4 protein, human|*Muscle Proteins|Biological Transport|Kinetics 271 SLC16A4 31479685 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111591 2 1 0 345 Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|SLC16A3 protein, human|Monocarboxylic Acid Transporters|SLC16A4 protein, human|*Apoptosis|Muscle Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|*Acid-Base Equilibrium|*Cytoplasm|Lactate|Hydrogen-Ion Concentration 271 SLC16A4 31418947 Cell Prolif. 2019 PMC6869122 10.1111/cpr.12673 2 7 0 345 Humans|*Interleukin-6|*NF-IL6|*Colon|SLC16A3 protein, human|*Monocarboxylic Acid Transporters|SLC16A4 protein, human|*Muscle Proteins|Inflammatory Bowel Disease|Zonula Occludens-1 Protein|Intestinal Mucosa|Caco-2 Cells|CREB1 protein, human|*Cyclic AMP Response Element-Binding Protein|NF-kappa B|Tumor Necrosis Factor-alpha|Epithelial Cells|Inflammation|*Defecation 271 SLC16A4 31239287 Mol. Cancer Res. 2019 PMC6726526 10.1158/1541-7786.MCR-18-1191 0 0 0 345 *Squamous Cell Carcinoma of Head and Neck|Monocarboxylic Acid Transporters|Glycolysis|Symporters|Fibroblasts|Muscle Proteins|Tumor Microenvironment|Cell Line, Tumor|Cancer-Associated Fibroblasts|Mitochondria|Stromal Cells|Coculture|Oxidative Stress|Epithelial Cells|Head and Neck Neoplasms|Smoking 271 SLC16A4 31201333 Nat Commun 2019 PMC6573034 10.1038/s41467-019-10566-6 4 3 0 345 Humans|Animals|Monocarboxylic Acid Transporters|Symporters|Amino Acid Sequence|Biological Transport|Molecular Conformation|Substrate Specificity|*Ion Transport|Xenopus laevis|Lactic Acid|Plasma Membranes|Hydrogen-Ion Concentration 271 SLC16A4 31177263 Med. Sci. Monit. 2019 PMC6582689 10.12659/MSM.912272 0 0 0 345 Humans|Neoplasm Recurrence, Local|SLC16A3 protein, human|*Monocarboxylic Acid Transporters|SLC16A4 protein, human|*Osteosarcoma|Prognosis|*Muscle Proteins|Kaplan-Meier Analysis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease Progression|Upregulation 271 SLC16A4 31177114 Anticancer Res. 2019 10.21873/anticanres.13405 0 0 0 345 Oncocytoma, renal|*Carcinoma, Renal Cell|*Immunohistochemistry|*Adenoma, Oxyphilic|*Kidney Neoplasms|*Kidney|Diagnosis, Differential|Biomarkers, Tumor 271 SLC16A4 31122841 EBioMedicine 2019 PMC6606928 10.1016/j.ebiom.2019.05.031 2 1 0 345 *Adenomatous Polyps|*Adenocarcinomas|*Bioenergetic|Colorectal Cancers|Oxidative Phosphorylation|*Rectal Neoplasms|*Intestinal Polyposis|Mitochondria 271 SLC16A4 31112527 J. Clin. Invest. 2019 PMC6668690 10.1172/JCI124012 3 3 0 345 Animals|*Multiple Sclerosis|*Glycolysis|SLC16A3 protein, human|Monocarboxylic Acid Transporters|SLC16A4 protein, human|Experimental Autoimmune Encephalomyelitis|*Macrophages|*Brain|Emmprin|Muscle Proteins|Leukocytes|siRNA|Lactate 271 SLC16A4 31101938 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03151-z 0 1 0 345 Animals|Humans|Monocarboxylic Acid Transporters|*Mutagenesis, Site-Directed|Symporters|*Amino Acids|*Molecular Dynamics Simulation|Substrate Specificity|Xenopus laevis|Amino Acid Sequence|Biological Transport|Muscle Proteins|*Models, Chemical|Hydrophobic Interactions|Mutagenesis|Oocytes 271 SLC16A4 31078621 Gastroenterology 2019 10.1053/j.gastro.2019.05.004 11 5 0 345 Mice|Animals|CA9 protein, human|*Carbonic Anhydrase IX|*Proto-Oncogene Proteins p21(ras)|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|Antigens, Neoplasm|gemcitabine|Deoxycytidine|*Hypoxia|Cell Line, Tumor|Signal Transduction|Cell Proliferation|Xenograft Model Antitumor Assays|Gene Expression Regulation, Neoplastic|Tumor Burden|Hydrogen-Ion Concentration 271 SLC16A4 31072911 Biochem. J. 2019 10.1042/BCJ20190177 3 0 0 345 Humans|CA9 protein, human|*Carbonic Anhydrase IX|*Glycolysis|Carbonic Anhydrases|Antigens, Neoplasm|Carbonic Anhydrase Inhibitors|*Phenotype|Cell Line, Tumor|Cell Hypoxia|Tumor Microenvironment|Sulfonamides|Cell Proliferation|Hydrogen-Ion Concentration|Lactic Acid 271 SLC16A4 31059031 Mol Med Rep 2019 10.3892/mmr.2019.10169 0 9 0 345 Humans|Male|Mice|Animals|*Testis|*Azoospermia|estradiol 3-benzoate|*Estradiol|Spermatogenesis|Sperm|Sertoli Cells|*Oxidative Stress|Monocarboxylic Acid Transporters|Glutathione Peroxidase|Glucose|Catalase|Superoxide Dismutase|RNA, Messenger 271 SLC16A4 31017677 J Labelled Comp Radiopharm 2019 10.1002/jlcr.3739 3 0 0 345 Humans|Monocarboxylic Acid Transporters|Symporters|Muscle Proteins|Cell Line, Tumor|Lactic Acid|Cell Proliferation 271 SLC16A4 30917457 Zhonghua Zhong Liu Za Zhi 2019 10.3760/cma.j.issn.0253-3766.2019.03.010 0 5 0 345 271 SLC16A4 30795533 Int J Mol Sci 2019 PMC6412294 10.3390/ijms20040937 2 0 0 345 Humans|*Introns|Greece|*Melanoma|Cancer, Skin|Carcinoma, Basal Cell|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Signal Transduction 271 SLC16A4 30699066 Biol. Chem. 2019 10.1515/hsz-2018-0411 0 2 0 345 bromopyruvate|*Pyruvates|Monocarboxylic Acid Transporters|*Colorectal Cancer|Symporters|Basigin|*Colonic Neoplasms|Glycolysis|Muscle Proteins|Cell Line, Tumor|Biological Transport 271 SLC16A9 31784090 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.11.137 0 6 0 89 Animals|Humans|Kinetics|Uric Acid|*Sodium|Biological Transport|Monocarboxylic Acid Transporters|Carrier Proteins|Xenopus laevis|Creatine|Cloning, Molecular|Oocytes|Plasma Membranes|*Ions|Hydrogen-Ion Concentration 30 SLC22A9 30824882 J. Hum. Genet. 2019 10.1038/s10038-019-0586-4 0 0 0 139 Humans|*Genome-Wide Association Study|Triiodothyronine|Thyroxine|*Thyroid Function Tests|Thyroid Hormones|Gland, Thyroid|Thyrotropin|Biological Transport|Cohort Studies 30 SLC25A24 31775791 BMC Med. Genet. 2019 PMC6882017 10.1186/s12881-019-0921-9 1 1 0 148 Humans|Female|Child|*Follow-Up Studies|Republic of Korea|Progeroid Syndrome, Congenital, Petty Type|*Progeria|*Growth Disorders|*Phenotypes|Gorlin Chaudhry Moss syndrome|Craniofacial Abnormalities|Abnormalities, Multiple|Hypertrichosis|Syndromes|Ductus Arteriosus, Patent|Mutation|SLC25A24 protein, human|Calcium-Binding Proteins|Antiporters|Mitochondrial Proteins 27 SLC25A38 31642437 Zhongguo Dang Dai Er Ke Za Zhi 2019 0 0 0 20 Child|Humans|*Anemia, Sideroblastic|5-Aminolevulinate Synthetase|*Mutation|Genetic Diseases, X-Linked|Mitochondrial Membrane Transport Proteins 35 SLC25A38 31338833 Br. J. Haematol. 2019 10.1111/bjh.16100 0 0 0 20 Male|Humans|Female|Child|X-linked sideroblastic anemia|Retrospective Studies|*Anemia, Sideroblastic|*Genetic Diseases, X-Linked|5-Aminolevulinate Synthetase|Mutations|*Genotype-Phenotype Correlations|Mitochondrial Membrane Transport Proteins|Iron Overload|Haem|Phenotype|Genotype|*Cohort Studies|ALAS2 protein, human|Slc25a38 protein, human 35 SLC25A38 31155012 Psychol Med 2019 PMC7068799 10.1017/S0033291719001144 0 0 0 20 *Schizophrenia|Hippocampus|Dentate Gyrus|Cognition|Organ Size|Magnetic Resonance Imaging 35 SLC25A38 30737140 Mol. Genet. Metab. 2019 10.1016/j.ymgme.2019.01.015 2 3 0 20 Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Aminolevulinic Acid|5-Aminolevulinate Synthetase|Genetic Diseases, X-Linked|*Porphyrias|Protoporphyria, Erythropoietic|Haem|GATA1 protein, human|GATA1 Transcription Factor|Binding Sites|Mutations|Missense Mutation|*Nitric Oxide Synthase|Protein Binding|ALAS2 protein, human|Slc25a38 protein, human|Mitochondrial Membrane Transport Proteins 35 SLC25A38 30660387 Mol. Genet. Metab. 2019 10.1016/j.ymgme.2018.12.012 1 2 0 20 Female|Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Ferrochelatase|*Genetic Diseases, X-Linked|5-Aminolevulinate Synthetase|Erythropoietic Protoporphyria|*Mutations|Haem|ALAS2 protein, human|GLRX5 protein, human|Glutaredoxins|Slc25a38 protein, human|Mitochondrial Membrane Transport Proteins 35 SLC31A2 31083932 Inorg Chem 2019 10.1021/acs.inorgchem.9b00711 0 0 0 125 Humans|Cation Transport Proteins|*Peptides|Copper|*Lysosomes|Protein Binding|Binding Sites|SLC31A1 protein, human|Copper Transporter 1|Models, Molecular|*Biophysical Phenomena|Hydrogen-Ion Concentration 28 SLC31A2 30652029 Signal Transduct Target Ther 2019 PMC6329797 10.1038/s41392-018-0034-5 4 0 0 125 Humans|*Antineoplastic Agents|Carboplatin|Cisplatin|Oxaliplatin|Organoplatinum Compounds|Cancer|*Machine Learning 28 SLC4A11 31833218 Physiol Rep 2019 PMC6908739 10.14814/phy2.14232 1 2 0 80 Mice|Female|Animals|*Sodium Chloride|*Submandibular Gland|Ion Transport|Antiporters|Sodium|Bicarbonates|Slc4a11 protein, mouse|Anion Transport Proteins|Symporters 104 SLC4A11 31774702 Am. J. Physiol., Cell Physiol. 2019 PMC7052617 10.1152/ajpcell.00425.2019 0 5 0 80 Humans|Anion Transport Proteins|Antiporters|Ion Transport|Corneal Dystrophies, Hereditary|Symporters|Biological Transport|Bicarbonates|HEK293 Cells|Sodium|Ammonia|Hydrogen-Ion Concentration|SLC4A11 protein, human 104 SLC4A11 31714402 Cornea 2019 10.1097/ICO.0000000000002183 0 0 0 80 *Fuchs' Endothelial Dystrophy|*Mutations|Anion Transport Proteins|Corneal Dystrophies, Hereditary|Antiporters|*Iridocorneal Endothelial Syndrome|Genotypes|*Chromosome Disorders 104 SLC4A11 31691803 Hum. Mol. Genet. 2019 10.1093/hmg/ddz259 0 8 0 80 Humans|HEK293 Cells|*Cell Adhesion|Fuchs Endothelial Corneal Dystrophy|Anion Transport Proteins|Antiporters|Corneal Dystrophies, Hereditary|SLC4A11 Protein|Mutations|Protein Transport|Mutation, Missense|*Iridocorneal Endothelial Syndrome|Amino Acid Sequence|Cell Membrane|SLC4A11 protein, human 104 SLC4A11 31555324 Front Genet 2019 PMC6726741 10.3389/fgene.2019.00881 0 0 0 80 104 SLC4A11 31491427 Exp. Eye Res. 2019 10.1016/j.exer.2019.107782 0 0 0 80 Humans|*SLC4A11 Protein|*Endoplasmic Reticulum-Associated Degradation|HEK293 Cells|Anion Transport Proteins|Antiporters|Corneal Dystrophies, Hereditary|Corneal Endothelium|Cell Membrane|Mutation|Protein Folding|Cornea|Transfections|*Homeostasis|SLC4A11 protein, human 104 SLC4A11 31420327 Br J Ophthalmol 2019 10.1136/bjophthalmol-2019-314377 0 0 0 80 104 SLC4A11 31323090 Invest. Ophthalmol. Vis. Sci. 2019 PMC6645617 10.1167/iovs.19-26930 0 0 0 80 *RNA Precursors|Corneal dystrophy and perceptive deafness|Corneal Dystrophies, Hereditary|*Corneal Endothelium|Anion Transport Proteins|Antiporters|Hearing Loss, Sensorineural|Pedigree|Mutation|Polymerase Chain Reaction|*RNA Splicing 104 SLC4A11 31273259 Sci Rep 2019 PMC6609610 10.1038/s41598-019-46094-y 0 0 0 80 Child|Humans|Corneal dystrophy, Fuchs' endothelial, 2|Fuchs Endothelial Corneal Dystrophy|Corneal Dystrophies, Hereditary|Anion Transport Proteins|*Cornea|Antiporters|Corneal Endothelium|Mutations|*Iridocorneal Endothelial Syndrome|Cell Membrane|HEK293 Cells|Protein Transport|SLC4A11 protein, human 104 SLC4A11 31254733 Redox Biol 2019 PMC6604051 10.1016/j.redox.2019.101260 1 0 0 80 Humans|*Glutamine|*Ammonia|Corneal Dystrophies, Hereditary|*Oxidative Stress|Anion Transport Proteins|*Mitochondria|Antiporters|Endothelium, Corneal|HEK293 Cells|SLC4A11 protein, human 104 SLC4A11 31124301 Physiol Rep 2019 PMC6533174 10.14814/phy2.14089 0 2 0 80 Rats|Mice|Animals|*SLC4A11 Protein|*Ammonia|*Membrane Transport Proteins|Loop of Henle|Kidney Concentrating Ability|Kidney Medulla|Aquaporin 1|*Adrenal Medulla|Slc4a11 protein, mouse|Anion Transport Proteins|Symporters 104 SLC4A11 30856043 Ophthalmic Genet. 2019 10.1080/13816810.2019.1571615 0 0 0 80 Humans|Corneal dystrophy and perceptive deafness|*Corneal Dystrophies, Hereditary|*Hearing Loss, Sensorineural|Anion Transport Proteins|*Mutation|Antiporters|Exons|Pedigree|Audiometry|Endothelium, Corneal|Polymerase Chain Reaction|Chile|SLC4A11 protein, human 104 SLFN11 31762822 J Cancer 2019 PMC6856579 10.7150/jca.32511 0 2 0 116 72 SLFN11 31682620 PLoS ONE 2019 PMC6827986 10.1371/journal.pone.0224267 1 0 0 116 Humans|*mRNA|Precision Medicine|*Biomarkers, Tumor|*Oncogenes|Drug Resistance, Neoplasm|*Gene Expression|*DNA|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Nuclear Proteins|DNA Damage|Gene Expression Profiling|SLFN11 protein, human 72 SLFN11 31632920 Front Oncol 2019 PMC6781860 10.3389/fonc.2019.00994 0 3 0 116 Humans|CD47 protein, human|*CD47 Antigen|*Topoisomerase Inhibitors|*Signal Transduction|*Ionizing Radiation|Genotoxic Stress|Cell Line, Tumor|Nuclear Proteins|Autophagy 72 SLFN11 31490091 Int. J. Radiat. Biol. 2019 10.1080/09553002.2019.1664787 2 0 0 116 72 SLFN11 31409613 Clin. Cancer Res. 2019 PMC6801079 10.1158/1078-0432.CCR-19-0419 0 1 0 116 olaparib|*Phthalazines|*Piperazines|Topoisomerase I Inhibitors|NSC 724998|Isoquinolines|*Cancer|*Homologous Recombination|indimitecan|Benzodioxoles|DNA Topoisomerases, Type I|Antineoplastic Agents 72 SLFN11 31395656 J. Biol. Chem. 2019 PMC6779438 10.1074/jbc.RA118.006588 0 4 0 116 Humans|*Interferon|Ataxia Telangiectasia Mutated Proteins|*Antiviral Agents|Cell Line, Tumor|Nuclear Proteins|DNA Damage|Drug Resistance, Neoplasm 72 SLFN11 31337055 Cells 2019 PMC6678517 10.3390/cells8070717 0 0 0 116 Animals|Humans|TH 302|*Squamous Cell Carcinoma of Head and Neck|*Tumor Hypoxia|*Heterografts|*Phosphoramide Mustards|pimonidazole|*Nitroimidazoles|Prodrugs|Chemoradiotherapy|Xenograft Model Antitumor Assays|Head and Neck Neoplasms|Cell Line, Tumor|Cell Hypoxia|*Disease Models, Animal 72 SLFN11 31278746 Clin. Genet. 2019 10.1111/cge.13600 1 0 0 116 Child|Humans|*Germ-Line Mutation|*DNA Copy Number Variations|*Genetic Predisposition to Disease|Genetic Testing|Neuroblastoma|Genotype|SOX4 protein, human|SOXC Transcription Factors|DICER1 protein, human|Ribonuclease III|DEAD-box RNA Helicases 72 SLFN12 31838790 Cell. Physiol. Biochem. 2019 PMC7007982 10.33594/000000191 0 0 0 86 Humans|*Triple-Negative Breast Cancer|Zinc Finger E-box-Binding Homeobox 1|Epithelial-Mesenchymal Transition|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|*Cell Differentiation|ZEB1 protein, human 24 SLFN12 31749907 ACS Med Chem Lett 2019 PMC6862344 10.1021/acsmedchemlett.9b00360 1 4 0 86 Cyclic Nucleotide Phosphodiesterases, Type 3|Gene Expression Regulation, Enzymologic 24 SLFN12 31598394 Am J Cancer Res 2019 PMC6780660 2 11 0 86 United States|*Phosphodiesterase 3A|anagrelide|*Cytokines|*Quinazolines|*Antineoplastic Agents|Apoptosis|Cell Line, Tumor|Cell Proliferation|Cell Cycle|*Cell Death|*Cell Transformation, Neoplastic|Signal Transduction 24 SLFN12 31420216 Mol. Cell 2019 10.1016/j.molcel.2019.06.040 7 4 0 86 Humans|Pregnancy|Female|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|*Apoptosis|Myeloid Cell Leukemia Sequence 1 Protein|*Estrogens|Apoptosis Regulatory Proteins|Caspases|Bcl-2-Like Protein 11|Mitochondria|*Proteolysis|HeLa Cells|Cell Line, Tumor|Intracellular Signaling Peptides and Proteins|Oestradiol|Membrane Proteins 24 SLFN12 31260507 PLoS ONE 2019 PMC6602453 10.1371/journal.pone.0219267 1 0 0 86 Humans|Male|Mice|Animals|*Mice, Knockout|*Cell Differentiation|Intestinal Mucosa|Enterocytes|*Biomarkers|DPP4 protein, human|Dipeptidyl Peptidase IV|Caco-2 Cells|Sucrase-Isomaltase Complex|Intestines|mRNA|Microfilament Proteins|*Gain, Weight|Pla2g2f protein, mouse|Group II Phospholipases A2 24 SLFN12 31026779 J. Mol. Graph. Model. 2019 PMC6657700 10.1016/j.jmgm.2019.04.003 0 4 0 86 Animals|Humans|Conserved Sequence|Amino Acid Sequence|*Gene Expression Regulation|E3 Ligase|Binding Sites|RNA Polymerase II|Amino Acid Motifs|Transcription, Genetic|Protein Binding|Sequence Homologs|Sequence Homology, Amino Acid|ATPase|RNA|Proteins|Protein Domains|SERPINB12 protein, human|Serpins|PDLIM7 protein, human 24 SLFN12 30875077 Hum. Cell 2019 PMC6571040 10.1007/s13577-019-00247-3 1 4 0 86 Humans|*Caco-2 Cells|*Butyrate|*Cell Differentiation|Cells, Epithelial|*Intestines|Enterocytes|Intestinal Mucosa|Proteins|Cell Movement|Peristalsis|Short-Chain Fatty Acids|siRNA 24 SLFN12 30662451 Front Genet 2019 PMC6329279 10.3389/fgene.2018.00682 1 0 0 86 *Cancer|CD274 protein, human|B7-H1 Antigen|*Oncogenes|Immunotherapy|CTLA4 protein, human|CTLA-4 Antigen|Data Mining|Databases, Genetic|*Gene Expression 24 SMARCAD1 31843968 J. Biol. Chem. 2019 PMC6983851 10.1074/jbc.RA119.008854 1 0 0 367 Humans|*Chromatin|*DNA Mismatch Repair|MutS Homolog 2 Protein|DNA-Binding Proteins|Nuclear Proteins|DNA Repair Enzymes|Base Pair Mismatch|MutL Proteins|*Apoptosis|Mismatch Repair Endonuclease PMS2|MutL Protein Homolog 1|DNA Repair|Adaptor Proteins, Signal Transducing|Carrier Proteins|Adenosine Triphosphatases|DNA Replication|DNA Damage|SMARCAD1 protein, human 50 SMARCAD1 31698199 DNA Repair (Amst.) 2019 10.1016/j.dnarep.2019.102733 2 2 0 367 Humans|*DNA Mismatch Repair|*Chromatin Assembly and Disassembly|Nucleosomes|Saccharomyces cerevisiae|Chromatin|MutS Homolog 2 Protein|Saccharomyces cerevisiae Proteins|Histones|Stability, Genome|DNA-Binding Proteins|Lynch Syndrome|Chromatin Assembly Factor-1|DNA|DNA-Directed DNA Polymerase|ATPase|SMARCAD1 protein, human|DNA Helicases|FUN30 protein, S cerevisiae 50 SMARCAD1 31648709 J. Am. Coll. Cardiol. 2019 10.1016/j.jacc.2019.08.1055 1 0 0 367 *Diabetes Mellitus, Type 2|Mendelian Randomization Analysis|Genome-Wide Association Study|Blood Glucose|Polymorphism, Single Nucleotide|Body Mass Index|Cardiovascular Diseases|*Phenotype|Blood Pressure|Risk Factors|Odds Ratio 50 SMARCAD1 31575705 Life Sci Alliance 2019 PMC6771652 10.26508/lsa.201900433 0 0 0 367 *Chromatin Assembly and Disassembly|Yeast, Fission|Schizosaccharomyces pombe Proteins|Chromosomal Proteins, Non-Histone|Nucleosomes|DNA Replication|DNA Repair|DNA, Fungal|Histones|Gene Expression Regulation, Fungal|Fft3 protein, S pombe 50 SMARCAD1 31555662 Front Mol Biosci 2019 PMC6737033 10.3389/fmolb.2019.00078 0 0 0 367 *Nucleosomes|Chromatin Assembly and Disassembly|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|DNA, Fungal|DNA Breaks, Double-Stranded|Chromatin|DNA Repair|Histones|Transcription Factors|Homologous Recombination|DNA Damage|FUN30 protein, S cerevisiae 50 SMARCAD1 31552267 Front Mol Biosci 2019 PMC6733915 10.3389/fmolb.2019.00079 6 0 0 367 Humans|DNA Breaks, Double-Stranded|BRCA1 protein, human|*BRCA1 Protein|Tumor Suppressor p53-Binding Protein 1|DNA End-Joining Repair|Chromatin|DNA Repair|Homologous Recombination|Histones|DNA|HeLa Cells 50 SMARCAD1 31301248 Clin Anat 2019 10.1002/ca.23432 0 0 0 367 Humans|Dermatoglyphics|Hand|*Hand Deformities, Congenital|*Skin Abnormalities|*Mass Screening|Cytogenetic|Recognition, Psychology|Health Personnel|Knowledge 50 SMARCAD1 31204252 Structure 2019 PMC6688830 10.1016/j.str.2019.05.003 3 1 0 367 *Ubiquitin|*Protein Binding|Chromatin Assembly and Disassembly|Tripartite Motif-Containing Protein 28|Chromatin|DNA Helicases|Binding Sites|Transcription Factors|Protein Domains|Protein Multimerization|Ubiquitylation|Crystallography, Xray 50 SMARCAD1 30919308 Biomol NMR Assign 2019 PMC6713675 10.1007/s12104-019-09888-9 0 0 0 367 Humans|DNA Helicases|Chromatin Assembly and Disassembly|Heterochromatin|Chromatin|DNA Repair|Histones|Protein Binding|Saccharomyces cerevisiae|ATPase|Protein Domains|SMARCAD1 protein, human 50 SMARCAD1 30902974 Nat Commun 2019 PMC6430823 10.1038/s41467-019-09078-0 2 35 0 367 *Endogenous Retroviruses|*Embryonic Stem Cells|Genes, Intracisternal A-Particle|Histones|Histone-Lysine N-Methyltransferase|Heterochromatin|DNA Methylation|Tripartite Motif-Containing Protein 28|Gene Silencing|Nuclear Proteins|Chromatin Assembly and Disassembly|Repressor Proteins|Cell Line|Retrotransposon|ATPase 50 SMARCAD1 30745850 Int. J. Biol. Sci. 2019 PMC6367592 10.7150/ijbs.29562 1 5 0 367 Humans|Pancreatic Cancer|Wnt Signaling Pathway|beta Catenin|Epithelial-Mesenchymal Transition|*Catenins|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Pancreas|*Neoplastic Processes|Cell Line, Tumor|Apoptosis|*Cell Transformation, Neoplastic|SMARCAD1 protein, human|DNA Helicases 50 Smarcal1 31857280 Yi Chuan 2019 10.16288/j.yczz.19-158 0 0 0 164 *Stability, Genome|DNA Helicases|DNA Replication|Osteochondrodysplasias|DNA, Single-Stranded|DNA Damage|Immunologic Deficiency Syndromes|Chromatin|Mutation 138 Smarcal1 31758253 Mamm. Genome 2019 PMC6884434 10.1007/s00335-019-09820-5 0 0 0 164 Male|Female|Sheep|Animals|*Phenotype|Breeding|Quantitative Trait, Heritable|Reproduction|Genome-Wide Association Study|Bone Morphogenetic Protein 15|Fertility|Polymorphism, Single Nucleotide|Gene Expression Regulation|Ethiopia 138 Smarcal1 31676232 Mol. Cell 2019 PMC7007862 10.1016/j.molcel.2019.10.008 5 1 0 164 *DNA Replication|Multifunctional Enzymes|DNA Primase|DNA-Directed DNA Polymerase|DNA, Single-Stranded|DNA Damage|DNA|Ultraviolet Rays 138 Smarcal1 31559731 Turk. J. Pediatr. 2019 10.24953/turkjped.2019.01.018 0 0 0 164 Male|Humans|Adolescent|*BK Virus|*Polyomavirus Infections|*Kidney|Nephrotic Syndrome|Renal Transplantation|Viremia|Osteochondrodysplasias|Immunosuppressive Agents|*Nephritis, Interstitial|*Transplants|Viral Load|DNA, Viral|Primary Immunodeficiency Diseases|*Pneumonia|SMARCAL1 protein, human|DNA Helicases 138 Smarcal1 31515241 Dis Model Mech 2019 PMC6826020 10.1242/dmm.039487 1 2 0 164 Spondyloepiphyseal dysplasia, congenita|Spondyloepiphyseal Dysplasia|Schimke immunoosseous dysplasia|Arteriosclerosis|Nephrotic Syndrome|DNA Helicases|DNA Replication|Immunologic Deficiency Syndromes|Primary Immunodeficiency Diseases|Pulmonary Embolism|*Induced Pluripotent Stem Cells|*Genetic Drift|Cell Differentiation 138 Smarcal1 31474762 Genet. Med. 2019 10.1038/s41436-019-0639-2 0 0 0 164 Child|Humans|*Moyamoya Disease|Whole Exome Sequencing|Exome|Intellectual Disability|Developmental Disabilities|Mutation|CNOT3 protein, human|Transcription Factors|CHD4 protein, human|Mi-2 Nucleosome Remodeling and Deacetylase Complex|SETD5 protein, human|Methyltransferases 138 Smarcal1 31423066 Indian J Nephrol 2019 PMC6668313 10.4103/ijn.IJN_95_18 0 0 0 164 Child|Male|Humans|Adolescent|Child, Preschool|Spondyloepiphyseal dysplasia, congenita|Schimke immunoosseous dysplasia|*Osteochondrodysplasias|*Nephrotic Syndrome|*Arteriosclerosis|*Primary Immunodeficiency Diseases|*Pulmonary Embolism|Immunologic Deficiency Syndromes|Focal Segmental Glomerulosclerosis|Kidney|DNA Helicases 138 Smarcal1 31308032 Ann. Clin. Lab. Sci. 2019 1 0 0 164 Child|Humans|*Nephrotic Syndrome|DNA Mutational Analysis|Mutation|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Genetic Predisposition to Disease|WT1 Proteins|Genotype|Chinese|China 138 Smarcal1 31275356 Front Genet 2019 PMC6591458 10.3389/fgene.2019.00565 1 0 0 164 *Whole Exome Sequencing|Schimke immunoosseous dysplasia|Osteochondrodysplasias|Nephrotic Syndrome|Arteriosclerosis|Primary Immunodeficiency Diseases|Immunologic Deficiency Syndromes|DNA Helicases|Pulmonary Embolism|Mutation 138 Smarcal1 31255466 Mol. Cell 2019 PMC6695479 10.1016/j.molcel.2019.05.026 0 0 0 164 *Cell Survival|BRCA1 protein, human|*BRCA1 Protein|RECQL protein, human|RecQ Helicases|Genomic Instability|DNA Replication|BRCA2 Protein|MRE11 Homologue Protein|Rad51 Recombinase|DNA-Binding Proteins|Endonucleases 138 Smoc2 31759926 Gastroenterology 2019 PMC7062567 10.1053/j.gastro.2019.11.031 0 22 0 125 Mice|Animals|*Hepatocyte Nuclear Factor 4|*Stem Cells|*Intestines|Intestinal Mucosa|Cell Differentiation|Cell Proliferation|Acids, Fatty 70 Smoc2 31694701 Acta Neuropathol Commun 2019 PMC6836495 10.1186/s40478-019-0795-2 0 0 0 125 Humans|*Alzheimer Disease|Amyloid beta-Peptides|*Proteomics|tau Proteins|*Biomarkers|Cognitive Impairment, Mild|Peptide Fragments|Early Diagnosis|*Plasma|Cohort Studies|Immunoassay|Research Design|STAMBP protein, human|Ubiquitin Thiolesterase|Endosomal Sorting Complexes Required for Transport 70 Smoc2 31613820 Chin. Med. J. 2019 PMC6831058 10.1097/CM9.0000000000000472 0 0 0 125 Humans|TYRP1 protein, human|*Membrane Glycoproteins|Calcium-Binding Proteins|Osteonectin|*Embryonic Development|SMOC1 protein, human 70 Smoc2 31306552 FEBS J. 2019 PMC6972655 10.1111/febs.14998 0 1 0 125 Humans|*Organoids|*Vitamin D|*Colon|*Vitamins|Receptors, Calcitriol|Calcitriol|*Stem Cells|Colonic Neoplasms|Colorectal Cancer|Cell Line, Tumor|Cell Proliferation|*Cholestanes 70 Smoc2 31263560 Evol Med Public Health 2019 PMC6592264 10.1093/emph/eoz015 1 0 0 125 Dogs|Animals|*Genome-Wide Association Study|*Domestication|Phenotype|Breeding|*Reproduction|Selection, Genetic|Genetic Variation 70 Smoc2 30936179 Development 2019 10.1242/dev.173161 0 0 0 125 Mice|Humans|Animals|*Sinoatrial Node|T-Box Domain Proteins|*Transcriptome Analysis|Homeodomain Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Heart Atria|Myocardium|Myocytes, Cardiac|Cell Differentiation 70 SMPDL3B 31495971 Xenotransplantation 2019 PMC7007337 10.1111/xen.12549 0 0 0 44 Animals|Swine|Humans|CD47 protein, human|*CD47 Antigen|*Baboon|*Podocytes|*Endothelial Cells|*Animals, Genetically Modified|*Phagocytosis|Transplantation, Heterologous|*Macrophages|Graft Survival|Graft Rejection|Galactosyltransferases|Kidney Transplantation|Membrane Cofactor Protein|Transplants|Gene Knockout Techniques 23 SMPDL3B 31487557 Biochim Biophys Acta Mol Cell Biol Lipids 2019 PMC6832884 10.1016/j.bbalip.2019.158517 1 1 0 44 Animals|Humans|*Podocytes|ceramide 1-phosphate|*Ceramides|ceramide kinase|Phosphotransferases (Alcohol Group Acceptor)|Sphingomyelinase|Signal Transduction|Sphingolipids|Phosphodiesterase 3B|Cell Proliferation|Cell Migration|*Cell Differentiation|Plasma Membrane|Protein Transport|Homeostasis|Inflammation|*Organogenesis|Phosphates 23 SMPDL3B 31217420 Nat Commun 2019 PMC6584700 10.1038/s41467-019-10584-4 5 3 0 44 Humans|Mice|Animals|*Diabetic Nephropathies|INSR protein, human|*Receptor, Insulin|Podocytes|*Signal Transduction|ceramide 1-phosphate|Ceramides|Sphingomyelin Phosphodiesterase|Insulin|Sphingolipids|Antigens, CD|Lipids|Membrane Microdomains|Diabetes Mellitus 23 SNCG 31333726 Cell. Mol. Biol. Lett. 2019 PMC6617888 10.1186/s11658-019-0172-y 2 0 0 3567 169 SNCG 31319533 Genes (Basel) 2019 PMC6678745 10.3390/genes10070539 2 0 0 3567 Female|Male|Animals|*Chickens|*Transcriptome Analysis|Gene Ontology|Transcriptome|Computational Biology|Feather|Breeding|*Biological Phenomena|Growth and Development|China 169 SNCG 31080399 Front Neurosci 2019 PMC6497738 10.3389/fnins.2019.00376 0 0 0 3567 Cricetinae|Animals|*Hibernation|*Medulla Oblongata|Potential, Action|Respiratory Center|Mesocricetus|Motor Neurons|*Adrenal Medulla|Temperature|Acclimatization 169 SNX10 31692073 J. Cell. Biochem. 2019 10.1002/jcb.29534 0 2 0 57 Humans|Mice|Animals|*Osteoclasts|*Lysosome|Endosomes|Bone Resorption|Sorting Nexin|Protein Transport|Phosphatidylinositol 3-Kinases|Binding Protein|Homeostasis|PIKFYVE protein, human|SNX10 protein, human|Pikfyve protein, mouse|OSTM1 protein, mouse|Membrane Proteins|SNX10 protein, mouse 51 SNX10 31589552 Metab Syndr Relat Disord 2019 10.1089/met.2019.0070 0 0 0 57 51 SNX10 31557715 iScience 2019 PMC6817687 10.1016/j.isci.2019.09.006 0 15 0 57 Humans|*Waist-Hip Ratio|Genome-Wide Association Study|Adipogenesis|Adipocytes|*Cell Differentiation|Insulin|PPAR gamma|Cell Line|CRISPR|*Regulatory Sequences, Nucleic Acid|Allele 51 SNX10 31356157 Immunohorizons 2019 PMC6686200 10.4049/immunohorizons.1900042 0 0 0 57 Humans|*DNA Methylation|*B-DNA|CpG Islands|*Pulmonary Macrophages|Epigenesis, Genetic|Lung|Bronchoalveolar Lavage Fluid|Bronchoalveolar Lavage|Sequencing, Next-Generation|Chronic Obstructive Pulmonary Disease|Cystic Fibrosis|*Biochemical Phenomena|*Protein Processing, Post-Translational 51 SNX10 31315669 Stem Cell Res Ther 2019 PMC6637500 10.1186/s13287-019-1316-8 2 0 0 57 Humans|*Induced Pluripotent Stem Cells|Osteopetrosis|Cellular Reprogramming|*Mutations|Osteoclast|Cell Differentiation|Cell Line 51 SNX10 31208298 Autophagy 2019 PMC7138201 10.1080/15548627.2019.1632122 2 1 0 57 Humans|Mice|Animals|*Sorting Nexins|*Autophagy|*Colorectal Cancer|Signal Transduction|*Disease Progression|CTNNB1 protein, human|beta Catenin|Lysosomes|*Colonic Neoplasms|HeLa Cells|Up-Regulation|Downregulation|SNX10 protein, human|SNX10 protein, mouse 51 SNX10 31186305 G3 (Bethesda) 2019 PMC6686932 10.1534/g3.119.400294 1 0 0 57 Humans|*Chromatin|Genome-Wide Association Study|*Adipose Tissue|Quantitative Trait Loci|*Phenotype|Chromosome Mapping|*Genomics|Obesity|Adipocytes|Alleles|Adipose Tissue, Subcutaneous|Polymorphism, Single Nucleotide|Gene Expression Profiling|Cardiovascular Diseases 51 SNX10 30898715 Gene 2019 10.1016/j.gene.2019.02.088 0 0 0 57 Infant|Humans|*Osteopetrosis|*Mutations|Genes, Recessive|Vacuolar Proton-Translocating ATPases|Homozygote|Pedigree|Base Sequence|Osteoclasts|TCIRG1 protein, human|SNX10 protein, human|Sorting Nexins 51 SNX10 30887568 J. Cell. Biochem. 2019 PMC6570537 10.1002/jcb.28606 0 0 0 57 Humans|Mice|Animals|*Osteoclasts|*Tacrolimus Binding Protein 1A|Bone Resorption|Sorting Nexin|*Protein Transport|Endosome|Endocytosis|Lysosome|*Cell Movement|SNX10 protein, human|SNX10 protein, mouse 51 SNX10 30885997 Blood Adv 2019 PMC6436016 10.1182/bloodadvances.2018025890 2 0 0 57 Humans|*Osteopetrosis|*Hematopoietic Stem Cell Transplantation|Transplantation Conditioning|Graft vs Host Disease|*Stem Cell Transplantation|Disease-Free Survival 51 SNX27 31820782 J. Cell Biol. 2019 PMC7039210 10.1083/jcb.201812098 0 1 0 396 Humans|Animals|Mice|*Podosomes|*Matrix Metalloproteinase 14|*SCID Mice|*Matrix Metalloproteinases|Neoplasm Invasiveness|Cell Line, Tumor|Sorting Nexin|Endosomes|Actin|Cell Movement|Protein Transport|Extracellular Matrix|Endocytosis|MT2-MMP|SNX27 protein, human|Snx27 protein, mouse 97 SNX27 31775031 Cell Rep 2019 PMC6899438 10.1016/j.celrep.2019.10.096 0 4 0 396 Humans|neuroligin 2|*Cell Adhesion Molecules, Neuronal|*Nerve Tissue Proteins|*Signal Transduction|Sorting Nexins|Endosomes|Protein Transport|PDZ Domains|Vesicular Transport Proteins|Protein Binding|HEK293 Cells|SNX27 protein, human 97 SNX27 31721175 Clin. Genet. 2019 10.1111/cge.13675 0 0 0 396 Humans|*Sorting Nexins|Endosomes|*Brain Diseases|*Seizures|Protein Transport|PDZ Domains|*Problem Behavior|HEK293 Cells|Cell Membrane|Brain|SNX27 protein, human 97 SNX27 31696214 Biosci. Rep. 2019 PMC6851508 10.1042/BSR20191692 0 0 0 396 Mice|Animals|*Sorting Nexins|Proteomics|*Wnt Signaling Pathway|Glycogen Synthase Kinase 3|Endosome|Protein Transport|PDZ Domain|Protein Binding|*Catenins|Carrier Proteins|Endocytosis|Transport Vesicles|Biological Transport|Amino Acid Sequence|Cell Movement|Snx27 protein, mouse 97 SNX27 31541095 Nat Commun 2019 PMC6754446 10.1038/s41467-019-12309-z 2 3 0 396 Humans|*Endosomes|Sorting Nexins|Protein Transport|PDZ Domain|Protein Binding|Vesicular Transport Proteins|HEK293 Cells|Plasma Membrane|HeLa Cells|Amino Acid Sequence|Binding Site|RNA, Small Interfering|SNX27 protein, human 97 SNX27 31216973 Biochemistry Mosc. 2019 10.1134/S0006297919020056 0 0 0 396 Humans|4-ethoxymethylene-2-phenyl-2-oxazoline-5-one|Sorting Nexins|*Oxazoles|Endosomes|Protein Binding|Amino Acid Sequence|PDZ Domains|Binding Sites|Protein Transport|Crystallography, X-Ray|Models, Molecular|Sequence Alignment|HEK293 Cells|SNX27 protein, human 97 SNX27 31182056 BMC Cancer 2019 PMC6558813 10.1186/s12885-019-5769-z 0 4 0 396 Humans|*Sorting Nexins|Cell Movement|Epithelial-Mesenchymal Transition|MCF-7 Cells|Cell Proliferation|Cadherins|beta Catenin|Vimentin|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Xenograft Model Antitumor Assays|Apoptosis|RNA, Small Interfering|RNA, Messenger 97 SNX27 31076513 J. Cell. Sci. 2019 10.1242/jcs.223172 0 2 0 396 *Actins|MMP14 protein, human|*Matrix Metalloproteinase 14|*Endosomes|*Matrix Metalloproteinases|*rhoB GTP-Binding Protein|Cell Movement|*Intracellular Membranes|Protein Transport|Neoplasm Invasiveness|Invadopodia|Extracellular Matrix|Cell Line, Tumor|Endocytosis|rho GTPase-activating protein|GTPase-Activating Proteins|Actin Cytoskeleton|Cytoskeleton 97 SNX27 31000624 Biochem. J. 2019 10.1042/BCJ20180620 3 5 0 396 Humans|*Diacylglycerol Kinase|*Protein Kinase C|1,2-diacylglycerol|Diglycerides|Receptors, Antigen, T-Cell|Signal Transduction|Protein Kinase C-alpha|Protein Transport|Jurkat Cells|Phosphatidic Acid|Synapse 97 SNX27 30897179 PLoS ONE 2019 PMC6428263 10.1371/journal.pone.0214059 0 4 0 396 Humans|Adult|*Human T-lymphotropic virus 1|Gene Products, tax|HTLV-I Infections|Tropical Spastic Paraparesis|Adult T-Cell Leukemia|PDZ Domains|Virus Replication|Viral Gene Products|Cell Line|Australia|Japan|Africa|Caribbean|SNX27 protein, human|Sorting Nexins 97 SNX27 30797171 Neurobiol. Aging 2019 10.1016/j.neurobiolaging.2019.01.011 0 3 0 396 Mice|Animals|*Alzheimer Disease|*Down-Regulation|Presenilin-1|Amyloid beta-Protein Precursor|Plaque, Amyloid|Amyloid beta-Peptides|*Disease Models, Animal|Mice, Transgenic|Hippocampus|Neurons|Phenotype|Snx27 protein, mouse|Sorting Nexins 97 SNX27 30661800 Curr. Biol. 2019 PMC6370945 10.1016/j.cub.2018.12.027 0 0 0 396 Animals|Wings, Animal|Drosophila|Drosophila Proteins|Drosophila melanogaster|Cell Polarity|*Intercellular Junctions|Membrane Proteins|Dishevelled Proteins|Body Patterning|LIM Domain Proteins|Frizzled Receptors|DNA-Binding Proteins|Pupa|Animals, Genetically Modified|Cadherins|Protein Transport|Endosomes|Protein Binding 97 SNX27 30619032 Front Neurol 2019 PMC6300502 10.3389/fneur.2018.01059 0 4 0 396 Mice|Animals|Injury, Spinal Cord|Recovery of Function|Microglia|Neurons|Corticospinal Tract|Apoptosis|Macrophages|Disease Models, Animal|Snx27 protein, mouse|Sorting Nexins 97 SNX27 30602588 Biochem. J. 2019 10.1042/BCJ20180504 2 3 0 396 Humans|*Sorting Nexins|neuroligin 2|Cell Adhesion Molecules, Neuronal|Nerve Tissue Proteins|Endosomes|Protein Transport|*Synapses|*Lysosomes|Vesicular Transport Proteins|PDZ Domains|Protein Binding|Cell Membrane|Disks Large Homolog 4 Protein|HEK293 Cells 97 SORCS2 31781574 Front Mol Biosci 2019 PMC6857517 10.3389/fmolb.2019.00122 0 0 0 141 Humans|MicroRNAs|Gene Expression Regulation, Neoplastic|RNAi|Triple Negative Breast Neoplasms|Cell Line, Tumor|Cell Movement|Cell Proliferation 54 SORCS2 31583078 F1000Res 2019 PMC6758832 10.12688/f1000research.19174.1 1 0 0 141 Receptors, Nerve Growth Factor|*Signal Transduction|Receptor, trkB|Brain-Derived Neurotrophic Factor|Neurotrophin 3|Receptor, trkC|Receptor, Nerve Growth Factor|Neurons 54 SORCS2 31450785 Cells 2019 PMC6769852 10.3390/cells8090962 0 0 0 141 Animals|Humans|*Huntington Disease|*Alzheimer Disease|Genome-Wide Association Study|HTT protein, human|*Huntingtin Protein|*Diabetes Mellitus|Disease Models, Animal 54 SORCS2 31156431 Front Pharmacol 2019 PMC6533533 10.3389/fphar.2019.00499 0 0 0 141 Mice|Animals|tropomyosin-related kinase-B, human|*Receptor, trkB|BDNF protein, human|Brain-Derived Neurotrophic Factor|NGFR protein, human|Receptors, Nerve Growth Factor|*Ethanol|*Withdrawal Symptoms|Nerve Tissue Proteins|Alcohol Use Disorder|Membrane Glycoproteins|Adaptor Proteins, Vesicular Transport|Hippocampus|Signal Transduction|SorCS2 protein, mouse|Receptors, Cell Surface 54 SORCS2 30840898 Cell Rep 2019 PMC6410498 10.1016/j.celrep.2019.02.027 3 15 0 141 Humans|Animals|Mice|*Neurons|Excitatory Amino Acid Transporter 3|*Oxidative Stress|*Epilepsy|Glutathione|Cysteine|*Protective Agents|Cell Death|*Amino Acid Transporter|Brain|Biological Transport|Reactive Oxygen Species|SORCS2 protein, human|Receptors, Cell Surface|SorCS2 protein, mouse|Nerve Tissue Proteins 54 SOSTDC1 31853533 Food Funct 2019 10.1039/c9fo02786f 0 0 0 169 Mice|Animals|guar gum|*Reishi|*Galactans|*Plant Gums|*Mannans|*Colorectal Cancer|Colon|Dietary Fiber|Cecum|*Polysaccharides|*Colonic Neoplasms|*Dietary Carbohydrates|Lipid Metabolism 122 SOSTDC1 31815038 Am J Cancer Res 2019 PMC6895453 0 1 0 169 Humans|*Stomach Neoplasms|*Signal Transduction|Smad Proteins|Downregulation|Intracellular Signaling Peptides and Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|*Stomach|Cell Line, Tumor|*Disease Progression|SOSTDC1 protein, human|Proteins 122 SOSTDC1 31529323 Graefes Arch. Clin. Exp. Ophthalmol. 2019 10.1007/s00417-019-04462-4 0 2 0 169 Humans|Adult|Animals|Rats|Retinal Pigment Epithelium|Retina|Gene Expression Regulation, Developmental|*Mammals|Cell Differentiation|RNA, Messenger|Immunohistochemistry|SOSTDC1 protein, human|Proteins 122 SOSTDC1 31391487 Sci Rep 2019 PMC6686024 10.1038/s41598-019-47930-x 0 0 0 169 Rats|Humans|Male|Adult|Animals|*Sertoli Cells|*Testis|*Down-Regulation|Sexual Maturation|*Spermatogenesis|Leydig Cells|SOSTDC1 protein, human|*Proteins|Sperm|Germ Cells|Rats, Transgenic|Signal Transduction|Hormones 122 SOSTDC1 31313025 Mol. Cell. Biochem. 2019 10.1007/s11010-019-03578-9 1 1 0 169 Rats|Animals|Osteogenesis|*Fracture Healing|Glycogen Synthase Kinase 3|*Wnt Signaling Pathway|Mesenchymal Stem Cells|Cell Differentiation|beta Catenin|RNA, Micro|Osteoblasts|*Catenins|Osteocalcin|Cells, Cultured|Upregulation|Alkaline Phosphatase 122 SOSTDC1 31312383 Am J Transl Res 2019 PMC6614606 0 0 0 169 *T-Lymphocytes, Regulatory|*Cell Differentiation|Germinal Center|T-Lymphocytes, Helper-Inducer|*Virus Diseases|B-Lymphocytes|Immunity, Humoral|SOSTDC1 protein, human|Signal Transduction 122 SOSTDC1 31133012 BMC Oral Health 2019 PMC6537368 10.1186/s12903-019-0788-3 0 0 0 169 Paired Box Transcription Factors|*Tooth, Supernumerary|Polymorphism, Single Nucleotide|PAX6 Transcription Factor|Genetic Predisposition to Disease|Eye Proteins|Homeodomain Proteins|Genotype|Repressor Proteins|Case-Control Studies 122 SOSTDC1 30835038 Curr Osteoporos Rep 2019 PMC6715281 10.1007/s11914-019-00503-3 0 0 0 169 *Osteoporosis|*Cell Differentiation|Wnt Signaling Pathway|Bone|Intercellular Signaling Peptides and Proteins|Glycoproteins|Hematopoietic Stem Cell Transplantation 122 SOSTDC1 30814306 J. Immunol. 2019 10.4049/jimmunol.1801157 0 0 0 169 Mice|Animals|*NK Cell|NK Cell Lectin-Like Receptor Subfamily A|*Cell Differentiation|T-Box Domain Proteins|Mice, Knockout 122 SOSTDC1 30776499 Bone 2019 PMC6458996 10.1016/j.bone.2019.02.012 0 3 0 169 Mice|Animals|*Multiple Myeloma|*Osteoblasts|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Bone Formation|Bone Morphogenetic Proteins|BMP2 protein, human|Wnt Proteins|Transforming Growth Factor beta|Cell Differentiation|Signal Transduction|beta Catenin|Bone Disease 122 SOSTDC1 30685825 J. Appl. Genet. 2019 PMC6373403 10.1007/s13353-019-00484-0 0 0 0 169 Cattle|Animals|Poland|Breeding|Selection, Genetic|Phenotype|Milk|Fertility|Polymorphism, Single Nucleotide 122 SOSTDC1 30628645 Mol Med Rep 2019 PMC6390060 10.3892/mmr.2019.9806 3 45 0 169 Dogs|Animals|Rats|Female|*Down-Regulation|*Febuxostat|*Kidney|*Epithelial Cells|Transforming Growth Factor beta1|BMP7 protein, human|Bone Morphogenetic Protein 7|Epithelial-Mesenchymal Transition|Fibrosis|Ureteral Obstruction|Signal Transduction|Kidney Diseases|Phosphorylation|*Uterus 122 SOX18 31881968 BMC Mol Cell Biol 2019 PMC6935224 10.1186/s12860-019-0245-9 0 0 0 209 Humans|*Stomach Neoplasms|*Stomach|PAX8 Transcription Factor|Gene Expression Regulation, Neoplastic|Cell Proliferation|RNA, Long Noncoding|SOXD Transcription Factors|Cell Line, Tumor|Signal Transduction|Prognosis|Transcription Factor|*Upper Gastrointestinal Tract|Autoantigens|PAX8 protein, human 195 SOX18 31825847 Cell Rep 2019 10.1016/j.celrep.2019.10.122 2 0 0 209 Humans|Female|*SOXF Transcription Factors|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Fallopian Tube|Cells, Epithelial|Gene Expression Regulation, Neoplastic|Ovary|Chromatin|SOX18 protein, human 195 SOX18 31536760 Semin. Cancer Biol. 2019 10.1016/j.semcancer.2019.09.008 0 0 0 209 *SOXF Transcription Factors|*Cell Transformation, Neoplastic|*Tumorigenesis|Gene Expression Regulation, Developmental|Neovascularization, Physiologic|Organogenesis|Amino Acid Sequence|Cell Differentiation 195 SOX18 31529503 Hepatology 2019 10.1002/hep.30951 1 15 0 209 Humans|*Carcinoma, Hepatocellular|FGFR4 protein, human|*Receptor, Fibroblast Growth Factor, Type 4|*Liver Neoplasms|*Up-Regulation|*Tyrosine Kinase|Neoplasm Recurrence, Local|FGF19 protein, human|*Fibroblast Growth Factors|Cell Line, Tumor|Cell Proliferation|Signal Transduction|*Transcriptional Activation|Disease Progression 195 SOX18 31527225 Mol. Cancer Ther. 2019 10.1158/1535-7163.MCT-19-0043 1 0 0 209 Humans|Mice|Animals|*Carcinoma, Renal Cell|cabozantinib|*SOX18 Transcription Factor|*Anilides|*Pyridines|Kidney Neoplasms|*Disease Progression|Mice, Nude|Cell Proliferation|Cell Movement|Cell Line, Tumor|Epithelial-Mesenchymal Transition|Down-Regulation|Carcinogenesis|Upregulation|Signal Transduction|SOX18 protein, human 195 SOX18 31427562 Med. Sci. Monit. 2019 PMC6713035 10.12659/MSM.915729 1 27 0 209 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Cell Survival|*Adenosine Monophosphate|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Epithelial-Mesenchymal Transition|*TOR Serine-Threonine Kinases|*Apoptosis|Cell Migration|Signal Transduction|Neoplasm Invasiveness|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Disease Progression|Hep G2 Cells|Cell Line, Tumor|Downregulation 195 SOX18 31358114 Elife 2019 PMC6667216 10.7554/eLife.43026 1 0 0 209 Humans|*Propranolol|*SOXF Transcription Factors|*Hemangioma|Hypotrichosis-Lymphedema-Telangiectasia Syndrome|Hypotrichosis|Telangiectasis|Lymphedema|Mutation|*Syndrome|SOX18 protein, human 195 SOX21 31761677 Stem Cell Reports 2019 PMC6915843 10.1016/j.stemcr.2019.10.013 0 4 0 81 Humans|*Human Embryonic Stem Cells|*Prosencephalon|SOX21 protein, human|*SOXB2 Transcription Factors|Neural Stem Cells|Cell Differentiation|Wnt Proteins|Wnt Signaling Pathway|Transcription Factor|Neurons|Gene Expression Regulation|Cells, Cultured|WNT8B protein, human 77 SOX21 31369759 Life Sci. 2019 10.1016/j.lfs.2019.116708 2 0 0 81 Humans|Female|*RNA, Long Noncoding|*Prognosis|*Uterine Cervical Neoplasms|*DNA Methylation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Regulatory Networks|Cell Proliferation|Cell Line, Tumor|Cell Movement|RNA, Messenger|Carcinogenesis|Disease Progression 77 SOX21 31234577 Genes (Basel) 2019 PMC6628375 10.3390/genes10060477 0 0 0 81 Humans|Dogs|Animals|*RNA, Long Noncoding|Melanomas|*Genome|Oral Cancers|Gene Expression Profiling 77 SOX21 30992391 Biosci. Rep. 2019 PMC6522742 10.1042/BSR20190602 3 0 0 81 Humans|*RNA, Anti-Sense|*Cell Proliferation|SOX21 protein, human|*SOXB2 Transcription Factors|lncRNA|*Nephroblastoma|Prognosis|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Carcinogenesis|Apoptosis|Biomarkers, Tumor|Promoter Regions, Genetic|Kidney Neoplasms 77 SOX21 30984807 Data Brief 2019 PMC6444121 10.1016/j.dib.2019.103717 0 0 0 81 *Transcriptome|Transcription Factor|Intestines|Endoderm|DNA-Binding Proteins|Inhibitor of Differentiation Protein 2|Gene Expression Regulation|Intestinal Mucosa|Cell Differentiation|*Microarray Analysis|Digestive System|Intestine, Small 77 SOX21 30912129 J. Cell. Physiol. 2019 10.1002/jcp.28371 6 12 0 81 Humans|Female|*RNA, Long Noncoding|*RNA, Anti-Sense|*Uterine Cervical Neoplasms|VDAC1 protein, human|*Voltage-Dependent Anion Channel 1|Epithelial-Mesenchymal Transition|*miRNA|SOX21 protein, human|*SOXB2 Transcription Factors|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Disease Progression|Neoplasm Invasiveness|Upregulation|Cell Movement|Cell Line, Tumor|*Neoplastic Processes|Oncogenesis 77 SOX8 31858753 J. Korean Med. Sci. 2019 PMC6926101 10.3346/jkms.2019.34.e312 1 0 0 109 Humans|Prognosis|Receptor, ErbB-2|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Kaplan-Meier Estimate|Tumor Stem Cells 165 SOX8 31784732 Nat. Genet. 2019 PMC6886578 10.1038/s41588-019-0534-4 2 1 0 109 *Histones|Acetylation|RNA Polymerase II|Histone Deacetylases|*Rhabdomyosarcoma|Transcription Factors|*Regulatory Gene|Transcription, Genetic|Chromatin Immunoprecipitation|Enhancer Elements, Genetic|Histone Deacetylase Inhibitors|Promoter Regions, Genetic|*Rhabdomyosarcoma, Embryonal|Protein Processing, Post-Translational 165 SOX8 31418589 DNA Cell Biol. 2019 10.1089/dna.2018.4586 0 0 0 109 Animals|*Genome|Perciformes|Fish Proteins|Sequence Alignment|Amino Acid Sequence|Phylogeny|Cloning, Molecular|Gene Expression Regulation, Developmental 165 SOX8 31277140 Medicine (Baltimore) 2019 PMC6635174 10.1097/MD.0000000000016237 1 0 0 109 Humans|*Retrospective Studies|*Colorectal Cancer|Prognosis|Neoplasm Staging|Immunohistochemistry|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Biomarkers, Tumor|Kaplan-Meier Estimate|MicroRNAs|Down-Regulation|*Colonic Neoplasms 165 SOX8 31194875 Nucleic Acids Res. 2019 PMC6649842 10.1093/nar/gkz523 3 0 0 109 Humans|*SOXE Transcription Factors|*Transcriptional Activation|SOX9 Transcription Factor|Gene Expression Regulation|Amino Acid Sequence|Protein Binding|Proteins|Mutations|SOX7 protein, human|SOXF Transcription Factors|SOX10 protein, human 165 SOX8 31007729 Exp Ther Med 2019 PMC6468394 10.3892/etm.2019.7349 0 0 0 109 *Transcriptome|Gene Regulatory Networks|Gene Expression Profiling|Transcription Factors|Oligonucleotide Array Sequence Analysis|Protein Interaction Maps|*Osteoporosis|Databases, Genetic 165 SOX8 30922563 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.03.096 0 0 0 109 Male|Humans|Adult|*Sertoli Cells|*Transcriptome|Blood-Testis Barrier|Spermatogenesis|Testis|SOXE Transcription Factors|*Transcriptome Analysis|SOX9 Transcription Factor|Tight Junctions|Sex Differentiation|Adherens Junctions|*Cell-to-Cell Interactions|Cell Differentiation|SOX4 protein, human|SOXC Transcription Factors 165 SOX8 30914279 Semin. Cancer Biol. 2019 10.1016/j.semcancer.2019.03.004 16 0 0 109 Humans|Male|SOX Transcription Factors|*Neoplastic Processes|Transcription Factors|*Cancer|High Mobility Group Proteins|Transcriptional Activation|SOXC Transcription Factors|Genes, sry|Tumor Microenvironment|SOX4 protein, human|SOX7 protein, human|SOXF Transcription Factors|SOX30 protein, human|Tumor Suppressor Proteins 165 SOX8 30902252 Curr. Top. Dev. Biol. 2019 PMC6955022 10.1016/bs.ctdb.2019.01.007 5 3 0 109 Humans|Animals|*SOX Transcription Factors|Chondrogenesis|SOX9 Transcription Factor|Chondrocyte|SOXD Transcription Factors|SOXC Transcription Factors|Cell Differentiation|Osteoblast|Proteins|SOX4 protein, human 165 SOX9 AND TGF? 31831024 J Orthop Surg Res 2019 PMC6909593 10.1186/s13018-019-1505-2 0 1 0 0 *Mesenchymal Stem Cells|*MAPK, p38|*Chondrogenesis|*Cell Differentiation|Chondrocytes|Bone Marrow Cells|SOX9 Transcription Factor|Collagen Type II|Transforming Growth Factor beta1|Signal Transduction|Aggrecans|Articular Cartilage 338 SOX9 AND TGF? 31645361 Genetics 2019 PMC6893390 10.1534/genetics.119.302527 0 0 0 0 Female|Male|*Testis|Sex Differentiation|Sex Determination Processes|Anti-Mullerian Hormone|Ovary|*Cell Differentiation|Gene Expression Regulation, Developmental|SOX9 Transcription Factor|Receptors, Transforming Growth Factor beta 338 SOX9 AND TGF? 31601652 J. Biol. Chem. 2019 PMC6873195 10.1074/jbc.RA119.009409 0 11 0 0 *Chondrogenesis|*Cell Differentiation|SOX9 Transcription Factor|Mesenchymal Stem Cells|*Signal Transduction|Chondrocytes|Collagen Type II|Aggrecans|*Transforming Growth Factor|Cells, Cultured|Transforming Growth Factor beta1|*Complement Factor B 338 SOX9 AND TGF? 31591875 J. Biol. Regul. Homeost. Agents 2019 10.23812/19-58-A 2 0 0 0 *Clodronic Acid|Diphosphonates|Articular Cartilage|Bone Density Conservation Agents|Knee Osteoarthritis|Pain|Knee Joint|Analgesics|Anti-Inflammatory Agents 338 SOX9 AND TGF? 31584200 J. Cell. Physiol. 2019 10.1002/jcp.29169 0 3 0 0 Mice|Animals|*Hepatic Stellate Cells|*Hepatectomy|Liver Regeneration|*Cell Signaling|*Progenitor Cells|Hepatocyte|Transforming Growth Factor beta|*Transforming Growth Factor|Liver Cirrhosis|Liver|Cell Proliferation|Transitions, Epithelial-Mesenchymal|Carrier Proteins 338 SOX9 AND TGF? 31581853 Connect. Tissue Res. 2019 10.1080/03008207.2019.1675649 0 0 0 0 338 SOX9 AND TGF? 31461224 Biotechnol. Prog. 2019 PMC7012688 10.1002/btpr.2897 0 5 0 0 Cattle|Animals|*Transforming Growth Factor beta|*Chondrogenesis|Chondrocytes|Cartilage, Articular|SOX9 protein, human|SOX9 Transcription Factor|Osteoarthritis|Receptors, Transforming Growth Factor beta|TGFBR1 protein, human|Receptor, Transforming Growth Factor-beta Type I|Proteoglycan|Signal Transduction|*Tissue Engineering 338 SOX9 AND TGF? 31409892 Lab. Invest. 2019 10.1038/s41374-019-0303-0 0 5 0 0 Humans|*Osteoarthritis|Chondrocytes|Cartilage, Articular|*Hypertrophy|Type II Collagen|Chondrogenesis|Type X Collagen|TGFB1 protein, human|Transforming Growth Factor beta1|Glycosaminoglycans|Cell Differentiation|Cells, Cultured|Wnt Pathway, Canonical|Pain|Apoptosis 338 SOX9 AND TGF? 31401976 BMC Dev. Biol. 2019 PMC6689882 10.1186/s12861-019-0198-4 0 2 0 0 Animals|Rabbits|*Chondrogenesis|*Hedgehog Proteins|Bone Marrow Stromal Cells|Bone Marrow Cells|Cartilage|Chondrocytes|Collagen Type II|SOX9 Transcription Factor|Cell Differentiation|Aggrecans|Cells, Cultured|Cell Proliferation|Transforming Growth Factor beta1|Signal Transduction 338 sp110 31665046 Virol. J. 2019 PMC6819563 10.1186/s12985-019-1231-8 0 0 0 198 Humans|Child|*Influenza, Human|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Computational Biology|Databases, Genetic|*Biomarkers|Cluster Analysis|Transcriptome 84 sp110 31485302 Oxid Med Cell Longev 2019 PMC6710736 10.1155/2019/9273056 1 0 0 198 Humans|*Tuberculosis|Polymorphism, Genetic|Genetic Predisposition to Disease 84 sp110 31031349 Lung India 2019 PMC6503728 10.4103/lungindia.lungindia_146_15 2 0 0 198 *Tuberculosis|Mycobacterium tuberculosis|*Genetic Polymorphism|Genetic Susceptibility|Toll-Like Receptor|Chemokines 84 sp110 30627224 Dis. Markers 2019 PMC6304864 10.1155/2018/4687380 4 1 0 198 Humans|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Asian Continental Ancestry Group|Tuberculosis, Pulmonary|Haplotypes|Minor Histocompatibility Antigens|Case-Control Studies|Nuclear Proteins|Odds Ratio|Risk Factors 84 SPAG16 30911868 J. Mol. Histol. 2019 10.1007/s10735-019-09817-z 1 1 0 28 Cricetinae|Male|Female|Animals|Mice|*Sperm|Microtubule Proteins|Cilia|Testis|Flagella|Axoneme|Microtubule-Associated Proteins|Chlamydomonas reinhardtii|Microtubules|Germ Cells|CHO Cells|Protein Isoforms|Sperm Flagellum|SPAG6 protein, mouse 28 SPAG6 31741713 Oncotarget 2019 PMC6849652 10.18632/oncotarget.27303 1 0 0 61 *DNA Methylation|*Early Detection of Cancer|*Liquid Biopsy|Promoter Regions, Genetic|Epigenetic|Biomarkers, Tumor|Epigenesis, Genetic|Proteinase Inhibitory Proteins, Secretory|Gene Expression Regulation, Neoplastic|Cell Free DNA 59 SPAG6 31660426 Mol Ther Oncolytics 2019 PMC6807308 10.1016/j.omto.2019.08.011 0 0 0 61 Humans|Male|Microtubule Proteins|*Microtubule|Cell Movement|Cell Proliferation|Apoptosis|Neurogenesis|*Cancers|Fibroblast|Spermatozoa 59 SPAG6 31185427 Aquat. Toxicol. 2019 10.1016/j.aquatox.2019.05.006 0 0 0 61 Animals|Male|*Testis|IMX-101|Anisoles|nitroguanidine|Guanidines|*Cyprinidae|Triazoles|Nitro Compounds|Transcriptomes|*Inferior Colliculi|Spermatogenesis 59 SPAG6 31146259 Reproduction 2019 10.1530/REP-18-0522 3 0 0 61 Humans|Male|Mice|Animals|Sperm Motility|*Spermatogenesis|Acrosome|Microtubule Proteins|Spermatozoa|Infertility, Male|Spermatids|Testes|Axoneme|Microtubule-Associated Proteins|Cilia|Spermatocytes|Chlamydomonas reinhardtii|Cytoskeleton|SNAPIN protein, human|Vesicular Transport Proteins|SPAG6 protein, mouse|SPINK2 protein, mouse 59 SPAG6 30911868 J. Mol. Histol. 2019 10.1007/s10735-019-09817-z 1 1 0 61 59 SPAG6 30835546 DNA Cell Biol. 2019 10.1089/dna.2018.4521 2 1 0 61 59 SPAG6 30686508 Am. J. Hum. Genet. 2019 PMC6372258 10.1016/j.ajhg.2018.12.013 9 0 0 61 59 SPANXA1 31289536 Oncol Lett 2019 PMC6546993 10.3892/ol.2019.10391 0 8 0 37 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Iodine|*Signal Transduction|*Thyroid Cancer|Cell Proliferation|Apoptosis|Downregulation|Cell Movement|Upregulation|Gene Silencing|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|Apoptosis Regulatory Proteins 27 SPATA16 31671693 Int J Mol Sci 2019 PMC6861889 10.3390/ijms20215418 0 0 0 7 Humans|Male|*Androgen-Insensitivity Syndrome|AR protein, human|Androgen Receptor|Exon|Frameshift Mutation|Mutation|Base Sequence|Pedigree|Sequence Analysis, DNA|Western Immunoblotting 33 SPATA16 31333723 Front Genet 2019 PMC6624472 10.3389/fgene.2019.00646 4 0 0 7 Male|Cattle|Animals|*RNA, Long Noncoding|*mRNA|Sequencing, RNA|Gene Expression Profiling|Spermatogenesis 33 SPATA16 30912172 Andrologia 2019 10.1111/and.13277 0 0 0 7 Humans|Male|*Sperm|Globozoospermia|DNA Fragmentation|Infertility, Male|Sperm Injections, Intracytoplasmic|Semen Analysis|*Cell Nucleus|Aneuploidy|Mutations|Membrane Proteins|SPATA16 protein, human|Vesicular Transport Proteins|DPY19L2 protein, human 33 SPDEF 31871532 World Allergy Organ J 2019 PMC6909348 10.1016/j.waojou.2019.100077 1 0 0 740 *Ion Transport|Chloride Channels|Goblet Cell|Respiratory Epithelium|Signal Transduction|Chlorides|*Biological Transport|*Biochemical Phenomena|Mucus 188 SPDEF 31835563 Pharmaceuticals (Basel) 2019 PMC6958407 10.3390/ph12040181 0 5 0 740 Humans|Male|*Prostate|*Prostate Cancer|PC3 Cells|Proto-Oncogene Proteins c-ets|YAP1 (Yes-associated) protein, human|*Adaptor Proteins, Signal Transducing|*Phosphoproteins|*Signal Transduction|Cell Line, Tumor|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|3'-(1-butylphosphoryl)adenosine|Cell Cycle|mRNA|Hippo protein, human|Protein-Serine-Threonine Kinases 188 SPDEF 31731782 Toxins (Basel) 2019 PMC6891430 10.3390/toxins11110670 0 0 0 740 Swine|Animals|deoxynivalenol|TFF3 protein, human|*Intestinal Trefoil Factor|Trichothecenes|Intestine|Cell Line|Peptides|Diets 188 SPDEF 31612022 Oncol Lett 2019 PMC6781494 10.3892/ol.2019.10885 1 0 0 740 Humans|Male|*Up-Regulation|Neoplasm Recurrence, Local|*Prostate Cancer|Prostate-Specific Antigen|Prostatectomy|Prognosis|Neoplasm Grading|Transcriptional Regulator ERG|*Transcriptional Activation|Biomarkers, Tumor|Proto-Oncogene Proteins c-ets|Tissue Array Analysis|Disease Progression|*Transcription Factor|SPDEF protein, human 188 SPDEF 31596609 Am. 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Pharmacol. 2019 10.1007/s00280-019-03891-6 3 1 0 740 Humans|Male|AR protein, human|*Androgen Receptor|*Prostate|Tamoxifen|estrogen receptor alpha, human|Estrogen Receptor alpha|Antineoplastic Agents, Hormonal|Receptors, Estrogen|Chemotherapy, Adjuvant|Prognosis|Disease-Free Survival|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 188 SPDEF 31278375 Mucosal Immunol 2019 10.1038/s41385-019-0181-1 0 2 0 740 Mice|Animals|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|Caspase 1|CARD Signaling Adaptor Proteins|Immunity, Innate|Streptococcus pneumoniae|Pneumococcal Pneumonia|Interleukin-1beta|ITLN1 protein, human|Cytokines|Inflammation|Apoptosis Regulatory Proteins|Gene Expression Regulation|Mice, Inbred C57BL|Caspases|Lung|Lectins|GPI-Linked Proteins 188 SPDEF 31188900 PLoS ONE 2019 PMC6561594 10.1371/journal.pone.0218263 2 0 0 740 Swine|Animals|*Genome-Wide Association Study|Quantitative Trait Locus|Phenotype|Single Nucleotide Polymorphisms|Sus scrofa|Breeding|Genotype|Adiposity|*Muscle|Bioinformatics 188 SPEF2 31770211 Medicine (Baltimore) 2019 PMC6890310 10.1097/MD.0000000000017997 1 0 0 21 *Nasopharyngeal Carcinoma|*Computational Biology|Neoplasm Recurrence, Local|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Software|Gene Expression Regulation, Neoplastic|Protein Interaction Mapping|Nasopharyngeal Neoplasms|Biomarkers, Tumor|Epistasis, Genetic 34 SPEF2 31545650 Am. 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Immunol. 2019 10.4049/jimmunol.1900021 1 1 0 154 *Spleen|Cross-Presentation|T-Lymphocytes, Cytotoxic|Cytotoxicity, Immunologic|Dendritic Cells|*Macrophages|Lymphocyte Activation|MHC Class I Molecules|*Infections, Viral 143 spic 31644907 Cell Rep 2019 PMC6870970 10.1016/j.celrep.2019.09.026 2 1 0 154 *B Cells|Pre-B-Cells|Transcription Factors|Gene Expression Regulation|Homeodomain Proteins|Transcription, Genetic|Trans-Activators|DNA Breaks, Double-Stranded|Immunoglobulin Light Chains|Tyrosine Kinase, SYK 143 spic 31440219 Front Microbiol 2019 PMC6693482 10.3389/fmicb.2019.01784 1 0 0 154 143 spic 31417692 R Soc Open Sci 2019 PMC6689652 10.1098/rsos.181696 0 0 0 154 *Dust|Power Plants|Coal|Particulate Matter|Air Pollution|Air Pollutants|Gases 143 spic 31405078 Pathogens 2019 PMC6789496 10.3390/pathogens8030124 1 0 0 154 Animals|Humans|Salmonella Infections, Animal|Chickens|Livestock 143 spic 31143160 Front Endocrinol (Lausanne) 2019 PMC6521701 10.3389/fendo.2019.00296 0 0 0 154 143 spic 31115226 Clin. Lab. 2019 10.7754/Clin.Lab.2018.181010 0 0 0 154 Infant|Humans|*Salmonella typhimurium|*Virulence|*Anti-Bacterial Agents|*Drug Resistance, Bacterial|Salmonella Infections|*Diarrhea|Microbial Sensitivity Tests|Drug Resistance, Multiple, Bacterial|Electrophoresis, Gel, Pulsed-Field|Serovar|Genetic Variation|China 143 spic 30680876 J. Pept. Sci. 2019 10.1002/psc.3140 1 0 0 154 Technetium|Organotechnetium Compounds|arginyl-glycyl-aspartic acid|Oligopeptides|Radiopharmaceuticals|Radionuclide Imaging|Isotope Labeling|Tissue Distribution|Coordination Complexes 143 spic 30674681 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6369774 10.1073/pnas.1820704116 3 1 0 154 Humans|Adult|Mice|Animals|*Lymphohistiocytosis, Hemophagocytic|Macrophages|*Communicable Diseases|Sepsis 143 spic 30630901 Science 2019 PMC6413693 10.1126/science.aao5213 9 2 0 154 TLR7 protein, human|*Toll-Like Receptor 7|*Toll-Like Receptor 9|*Signal Transduction|*Cell Differentiation|Myeloid Differentiation Factor 88|Membrane Glycoproteins|Inflammation|Macrophages|*Anemia 143 SPOCK2 31794425 Aging (Albany NY) 2019 PMC6932902 10.18632/aging.102538 0 0 0 42 Humans|Female|*RNA, Long Noncoding|MIRN363 microRNA, human|*Pseudogenes|*Carcinoma, Ovarian Epithelial|*MicroRNAs|*Ovarian Cancer|Gene Expression Regulation, Neoplastic|*Disease Progression|Gene Regulatory Networks|Gene Expression Profiling|Down-Regulation|Up-Regulation 35 SPOCK2 31341044 J. Virol. 2019 PMC6798107 10.1128/JVI.00662-19 0 2 0 42 Mice|Animals|*Interferon|*Proteoglycan|*Antiviral Agents|Orthomyxoviridae Infections|*Cells, Epithelial|Influenza A virus|*Lung|Influenza, Human|Virus Replication|Alveolar Epithelial Cells|Cell Line|Host-Pathogen Interactions|Virus Attachment|Recombinant Proteins 35 SPOCK2 31338255 PeerJ 2019 PMC6628882 10.7717/peerj.7163 0 7 0 42 Humans|Male|*Matrix Metalloproteinase 2|*Matrix Metalloproteinase 14|*Up-Regulation|*Prostate|*Prostate Cancer|Matrix Metalloproteinase Inhibitors|*Transcriptional Activation|Cell Movement|RNA, Messenger|MMP2 protein, human 35 SPOCK2 31242033 Arterioscler. Thromb. Vasc. Biol. 2019 PMC6597191 10.1161/ATVBAHA.119.312388 0 4 0 42 Animals|Mice|Endothelial Cells|Wnt Pathway|Axin Protein|beta Catenin|*Catenins|Blood-Brain Barrier|Central Nervous System|*Extracellular Matrix|*Organogenesis 35 SPOCK2 30832559 Reprod Sci 2019 10.1177/1933719119834341 3 7 0 42 Humans|Female|*Matrix Metalloproteinase 2|MMP14 protein, human|*Matrix Metalloproteinase 14|*Endometrial Cancer|Cell Proliferation|Transfections|Cell Line, Tumor|RNA, Messenger|*Endometrium|Upregulation|MMP2 protein, human 35 SPOCK2 30747904 Pain 2019 PMC7066867 10.1097/j.pain.0000000000001514 3 0 0 42 Humans|Genome-Wide Association Study|*Risk Factors|Multifactorial Inheritance|Genetic Predisposition|Polymorphism, Single Nucleotide|Neuroticism|Depressive Disorder, Major|Case-Control Studies|Depression|Phenotype|*Back Pain 35 srpx 31842516 Int J Mol Sci 2019 PMC6940909 10.3390/ijms20246283 1 0 0 33 *Oncogenes|*Cell Transformation, Neoplastic|*Oncogenesis|Tumors|Gene Expression Regulation, Neoplastic|Signal Transduction 50 srpx 31638245 Oncol. Rep. 2019 10.3892/or.2019.7379 0 0 0 33 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cystadenocarcinoma, Serous|Neoplasm Invasiveness|RHOA protein, human|rhoA GTP-Binding Protein|Cancer-Associated Fibroblasts|*Fibroblasts|Cell Movement|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|TYRP1 protein, human|*Membrane Glycoproteins|Biomarkers, Tumor|Cell Proliferation|Upregulation|Survival Rates 50 srpx 31364721 Int. J. Mol. Med. 2019 PMC6713409 10.3892/ijmm.2019.4291 1 0 0 33 Humans|Mice|Animals|*Constriction|Gene Ontology|Bioinformatics|Gene Expression Profiles|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Databases, Genetic|Protein Interaction Mapping|Software|Gene Expression Regulation, Neoplastic|*Aortic Valve Stenosis|*Heart|Downregulation|Upregulation|LTBP2 protein, human|Latent TGF-beta Binding Proteins|FSTL1 protein, human 50 srpx 30917865 Clin Epigenetics 2019 PMC6438015 10.1186/s13148-019-0651-z 0 2 0 33 Humans|Male|*Prostate|*Prostate Cancer|CpG Islands|DNA Methylation|*Disease Progression|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|*Neoplastic Processes|Androgens|Cell Line, Tumor|Carcinogenesis|TET2 protein, human|DNA-Binding Proteins|Proto-Oncogene Proteins 50 srpx 30630900 Science 2019 PMC6366617 10.1126/science.aao4827 31 3 0 33 *Amyloid beta-Protein Precursor|Synapses|Amyloid beta-Peptides|Amyloid Precursor Protein Secretases|Alzheimer Disease|Synaptic Transmission|Long-Term Potentiation|Hippocampus|Neuronal Plasticity|Neurons|gamma-Aminobutyric Acid 50 srpx2 31650880 J. Neurotrauma 2019 10.1089/neu.2019.6739 0 0 0 105 Humans|Male|Animals|Rats|*Down-Regulation|*Hypothalamus|*Traumatic Brain Injury|Brain Injuries|SRPUL protein, human|Membrane Proteins|Neurons|Nerve Tissue Proteins|Brain|Blotting, Western|Neoplasm Proteins|RNA, Messenger|*Genes, X-Linked 75 srpx2 31568004 Medicine (Baltimore) 2019 PMC6756728 10.1097/MD.0000000000017267 0 0 0 105 Humans|*Computational Biology|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|SRPUL protein, human|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|MicroRNAs|mRNA|Databases, Genetic|Biomarkers, Tumor|Genes, Regulator|Cluster Analysis|*Epithelium|Membrane Proteins|*Smoking|MUCL1 protein, human 75 srpx2 31362033 Neuroscience 2019 10.1016/j.neuroscience.2019.07.040 0 0 0 105 Mice|Animals|PLAUR protein, human|Plasminogen Activator Receptor, Urokinase Type|PLAU protein, human|*Membrane Proteins|SRPUL protein, human|*Hypothalamus|Urokinase-Type Plasminogen Activator|*Neoplasm Proteins|Mice, Inbred C57BL|Nerve Tissue Proteins|Traumatic Brain Injury|*Genotype|*Genes, X-Linked|Signal Transduction 75 srpx2 31258775 J Cancer 2019 PMC6584922 10.7150/jca.32072 4 1 0 105 75 srpx2 31056551 Genet. Med. 2019 10.1038/s41436-019-0531-0 2 0 0 105 Humans|*Epilepsy|*Disorder, Neurodevelopmental|Genetic Testing|Genetic Association Studies|Genetic Predisposition to Disease|Genetic Variation 75 srpx2 30795533 Int J Mol Sci 2019 PMC6412294 10.3390/ijms20040937 2 0 0 105 Humans|*Introns|Greece|*Melanoma|Cancer, Skin|Carcinoma, Basal Cell|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Signal Transduction 75 srpx2 30662000 EBioMedicine 2019 PMC6413340 10.1016/j.ebiom.2019.01.017 7 13 0 105 *Stomach Neoplasms|*Cell Signaling|*Glycans|Glycosylation|Gene Expression Regulation, Neoplastic|*Phenotype|Cell Movement|Cell Line, Tumor|sialosyl-Tn antigen|Antigens, Tumor-Associated, Carbohydrate|Cell Proliferation|Cell Transformation, Neoplastic|Carcinogenesis|Gene Expression Profiling 75 STEAP4 31788832 Ann. Neurol. 2019 10.1002/ana.25658 0 0 0 257 *Restless Legs Syndrome|*DNA Mutational Analysis|Pedigree|Lod Score|Chromosome Mapping|Genetic Predisposition to Disease|Genotype|Genetic Loci|Phenotype|Nerve Tissue Proteins 89 STEAP4 31648990 EBioMedicine 2019 PMC6838432 10.1016/j.ebiom.2019.08.074 1 9 0 257 *Urinary Bladder Neoplasms|*Phosphorylation|*RNA, Circular|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|RNA Interference|Cell Proliferation|3' Untranslated Regions|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Signal Transduction 89 STEAP4 31465999 iScience 2019 PMC6718828 10.1016/j.isci.2019.08.016 2 2 0 257 Humans|Animals|*Interferon-alpha|*Chiroptera|*B Virus|*Transcriptome|IFNL3 protein, human|Antiviral Agents|Interferon-beta|Immunity, Innate|Tetherin|Base Sequence 89 STEAP4 31393902 PLoS ONE 2019 PMC6687176 10.1371/journal.pone.0220456 1 0 0 257 Humans|Male|Neoplasm Recurrence, Local|*Prostate Cancer|PSCA protein, human|*Antigens, Neoplasm|*Neoplasm Proteins|Prostate|*Prognosis|Gleason Score|*Membrane Proteins|Immunohistochemistry|*GPI-Linked Proteins|Biomarkers, Tumor|Adenocarcinoma|Kaplan-Meier Analysis|Oxidoreductases 89 STEAP4 31062756 Anatol J Cardiol 2019 PMC6528516 10.14744/AnatolJCardiol.2019.11456 1 2 0 257 Rats|Animals|*Myocardial Reperfusion Injury|*Metformin|*Signal Transduction|Myocytes, Cardiac|Apoptosis|Cardiotonic Agents|Proto-Oncogene Proteins c-akt|Myocardium|Rats, Sprague-Dawley|Mitochondria 89 STIM2 31842580 Physiol Res 2019 10.33549/physiolres.934300 0 0 0 324 Animals|Humans|Heart Transplantation|Tissue Donors|STIM1 protein, human|Stromal Interaction Molecule 1|Stromal Interaction Molecule 2|Calcium Release Activated Calcium Channels|Calcium Signaling|Calcium Channels|*Isoforms|Calcium|Neoplasm Proteins|*Heart Failure 299 STIM2 31698854 Int J Mol Sci 2019 PMC6888010 10.3390/ijms20225539 1 0 0 324 Animals|Mice|*Calcium|ORAI1 Protein|*Hippocampus|Stromal Interaction Molecule 1|Stromal Interaction Molecule 2|Calcium Channels|*Gene Expression|*Epilepsy|Neurons|Cerebral Cortex|Homeostasis 299 STIM2 31540978 Clin. Cancer Res. 2019 PMC6858959 10.1158/1078-0432.CCR-19-2270 0 0 0 324 299 STIM2 31498847 PLoS ONE 2019 PMC6733454 10.1371/journal.pone.0222341 0 2 0 324 Rats|Animals|*Myocytes, Cardiac|*Glucocorticoids|Calcium Channels|Calcium Signaling|ORAI1 Protein|TRPC Cation Channels|Immediate-Early Proteins|Calcium Channel Blockers|*Hippocampus|Protein-Serine-Threonine Kinases 299 STIM2 31475744 Prostate 2019 10.1002/pros.23904 1 2 0 324 Humans|Male|Neoplasm Recurrence, Local|*Prostatectomy|*Prostate Cancer|*Prostate|Prostate-Specific Antigen|Prognosis|Neoplasm Staging|*Seminal Vesicles|Biomarkers, Tumor|Retrospective Studies 299 STIM2 31464639 Breast Cancer Res. 2019 PMC6716836 10.1186/s13058-019-1185-1 0 8 0 324 *Stromal Interaction Molecule 2|*Signal Transduction|Epithelial-Mesenchymal Transition|Transforming Growth Factor beta1|Gene Expression Regulation, Neoplastic|*Transforming Growth Factor|*Upregulation|Cell Movement|Cell Line, Tumor|Cell Proliferation|*Transcriptional Activation|*Calcium, Dietary|T-Lymphocytes 299 STIM2 31417547 Front Immunol 2019 PMC6685097 10.3389/fimmu.2019.01737 0 6 0 324 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one|*Gastrointestinal Microbiome|Stromal Interaction Molecule 1|ORAI1 Protein|Stromal Interaction Molecule 2|*Coumarins|Calcium Channels|Calcium Signaling|Calcium|urolithin B|Membrane Glycoproteins 299 STIM2 31396401 Cell Death Discov 2019 PMC6680047 10.1038/s41420-019-0203-5 0 0 0 324 Stromal Interaction Molecule 1|ORAI1 Protein|Calcium|Calcium Signaling|Calcium Channels|Endoplasmic Reticulum|Membrane Proteins|Neoplasm Proteins 299 STIM2 31346235 Sci Rep 2019 PMC6658661 10.1038/s41598-019-47259-5 0 5 0 324 *Muscle Development|*Transcription Factors|Stromal Interaction Molecule 1|ORAI1 Protein|Stromal Interaction Molecule 2|Calcium Signaling|Calcium Channels|Calcium|Endoplasmic Reticulum|Cell Membrane 299 STK17B 31292051 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2019 0 0 0 215 Humans|*Computational Biology|*Neutrophils|Gene Ontology|*Sepsis|Profile, Gene Expression|Software|Protein Interaction Maps|Gene Expression Profiling|Gene Regulatory Networks|Databases, Genetic|Protein Interaction Mapping|Gene Expression Regulation, Neoplastic|Signal Transduction|Microarray Analysis|Genetic Testing 32 STK33 31578828 Mol Genet Genomic Med 2019 PMC6900393 10.1002/mgg3.983 1 0 0 144 Humans|*Suicide, Attempted|*Genome-Wide Association Study|Suicidal Ideation|Study, Genetic Association|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Risk Factors|Mexico 48 STK33 31544703 Anticancer Agents Med Chem 2019 10.2174/1871520619666190507100912 0 1 0 144 Humans|*Cisplatin|Carcinoma, Non-Small-Cell Lung|Lung Cancer|*Lung Adenocarcinoma|*Protein-Serine-Threonine Kinases|Adenocarcinoma|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Apoptosis|Up-Regulation|Transcriptional Activation|STK33 protein, human 48 STK33 31537781 Nat Commun 2019 PMC6753076 10.1038/s41467-019-12011-0 0 49 0 144 Humans|*Tyrosinemias|*Signal Transduction|*Protein-Serine-Threonine Kinases|Ubiquitin-Protein Ligases|Ubiquitination|Nuclear Proteins|*Dioxygenases|Phosphorylation|*Acidosis|HEK293 Cells|PELI1 protein, human|STK33 protein, human 48 STK33 31272359 Anticancer Agents Med Chem 2019 0 2 0 144 Mice|Animals|MAPK1 protein, human|*Mitogen-Activated Protein Kinase 1|*Tumorigenesis|*Cell Transformation, Neoplastic|*Colorectal Cancer|*Colonic Neoplasms|*MAP Kinase Signaling System|*Signal Pathway|Phosphorylation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Mice, Nude 48 STK33 31261148 Neuroendocrinology 2019 10.1159/000501829 2 0 0 144 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|Cell Proliferation|*Disease Progression|Signal Transduction|Cell Line, Tumor|*Adenoma, Islet Cell|Pancreatic Neoplasms|Cell Movement|Gene Expression Regulation, Neoplastic|STK33 protein, human|Protein-Serine-Threonine Kinases 48 STK33 31131446 J. Cell. Physiol. 2019 PMC6772109 10.1002/jcp.28835 3 0 0 144 Humans|*Prognosis|*Head and Neck Cancer|Squamous Cell Carcinoma of Head and Neck|DNA Methylation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Epigenesis, Genetic|Bioinformatics|*Gene Expression|Microarray Analysis|INSM1 protein, human|Repressor Proteins 48 STK33 30760631 Biosci. Rep. 2019 PMC6395305 10.1042/BSR20182351 1 18 0 144 Mice|Animals|MAPK1 protein, human|*Extracellular Signal Regulated Kinase 2|*Tumorigenesis|*Colorectal Cancer|*Cell Transformation, Neoplastic|*Colonic Neoplasms|Phosphorylation|Apoptosis|Cell Proliferation|Signal Transduction|Cell Line, Tumor|Mice, Nude|Xenograft Model Antitumor Assays|RNA Interference 48 STK40 31092598 J. Biol. Chem. 2019 PMC6597834 10.1074/jbc.RA119.007840 0 7 0 141 Animals|Mice|Nuclear Proteins|Ubiquitin-Protein Ligases|Protein-Serine-Threonine Kinases|Cell Differentiation|Endoderm|Protein Binding 24 STOML1 30950057 J. Cell. Physiol. 2019 10.1002/jcp.28600 1 0 0 71 Humans|*RNA, Long Noncoding|*Protein A|Prognosis|Kaplan-Meier Analysis|Gene Expression Regulation, Neoplastic|*Lymphatic Metastasis|Gene Expression Profiling|Biomarkers, Tumor|Transcriptome|Proportional Hazards Models|Open Reading Frames|ROC Curve|Lymph Nodes|TFCP2 protein, human|DNA-Binding Proteins|Transcription Factors 20 STRC 31884617 Adv. Exp. Med. Biol. 2019 10.1007/978-3-030-27378-1_38 0 0 0 12 Male|Humans|Female|Child, Preschool|Middle Aged|Adolescent|Retinal Dystrophy, Early Onset Severe|*Retinal Dystrophy|Deafness, Autosomal Recessive 16|*Hearing Loss, Sensorineural|Deafness enamel hypoplasia nail defects|Amelogenesis Imperfecta|Leber Congenital Amaurosis|Abnormalities, Nail|Peroxisome biogenesis disorders|Peroxisomal Disorders|Mutation|Sequencing, Whole Exome|Pedigree|Retina|ATPases Associated with Diverse Cellular Activities|Membrane Proteins|Mutation, Missense|Phenotype 100 STRC 31776257 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6926040 10.1073/pnas.1902781116 2 0 0 12 Mice|Animals|*Tectorial Membrane|*Hair Cells, Auditory, Outer|*Stereocilia|Deafness, Autosomal Recessive 16|Hearing Loss, Sensorineural|Deafness|*Hair Cells, Vestibular|Sound|Proteins|Microscopy, Electron, Scanning 100 STRC 31706454 Acta Otorrinolaringol Esp 2019 10.1016/j.otorri.2019.05.005 0 0 0 12 Humans|Child|Pilot Projects|*Hearing Loss, Sensorineural|*Hearing Loss|*Deafness|*Sequencing, Next-Generation|Connexins|Mutation|Genomics|Asian Continental Ancestry Group 100 STRC 31645979 Hum Genome Var 2019 PMC6804619 10.1038/s41439-019-0075-5 0 0 0 12 *DNA Copy Number Variations|Homozygote|Hearing Loss, Sensorineural|Membrane Proteins 100 STRC 31552524 Eur Arch Otorhinolaryngol 2019 10.1007/s00405-019-05649-5 0 0 0 12 Humans|Deafness, Autosomal Recessive 16|*Hearing Loss, Sensorineural|*Mutations|Connexins|Connexin 26|Hearing Loss|Genetic Testing|Gene Frequency|Phenotype|Genotype|Pseudogene|Genotype-Phenotype Correlations|Membrane Proteins|Nonsyndromic Deafness|Deafness|STRC protein, human 100 STRC 31425884 Respir Physiol Neurobiol 2019 10.1016/j.resp.2019.103281 0 0 0 12 Muscle Fatigue|Exercise Tolerance|Physical Endurance|Oxygen Consumption|Bicycling|Respiratory Muscles|Exercise Test|Muscle Contraction|Exercise|Electromyography|*Fatigue 100 STRC 31320724 Sci Rep 2019 PMC6639340 10.1038/s41598-019-46966-3 2 0 0 12 Mice|Animals|*Intestinal Epithelium|*Intestines|*Transcriptome Analysis|Enterocytes|Transcriptome|Stem Cells|*Aging 100 STRC 31218851 Mol Genet Genomic Med 2019 PMC6687617 10.1002/mgg3.806 1 0 0 12 Humans|Male|Infertility, Male|Seminal Plasma Proteins|Deafness|Hearing Loss, Sensorineural|Membrane Proteins|Chromosome Mapping|Chromosome Deletion|Calcium Channels|Allele|STRC protein, human 100 STRC 31083078 Otol. Neurotol. 2019 10.1097/MAO.0000000000002234 0 0 0 12 Humans|*African Americans|*Hearing Loss|*Deafness|Connexin 26|Connexins|Gene Frequency|Genotype|Mutation 100 STRC 30966340 Polymers (Basel) 2019 PMC6415111 10.3390/polym10030305 0 0 0 12 *Hydrogel|*Cost-Benefit Analysis|*Dressing|Polyvinyl Alcohol|Wound Healing|carbopol 940|Acrylic Resins|Tensile Strength|Materials Testing|Anti-Bacterial Agents 100 STRC 30956637 EXCLI J 2019 PMC6449677 1 0 0 12 Glycogen Storage Disease IB|*Glycogen Storage Disease Type I|Glucose-6-Phosphatase|Monosaccharide Transport Proteins|Antiporters 100 STRC 30894395 Genome Res. 2019 PMC6442396 10.1101/gr.234443.118 20 0 0 12 Humans|*Genome, Human|Sequencing, Whole Genome|Sequence Analysis, DNA|Haplotypes|High-Throughput Nucleotide Sequencing|Genomics|Gene Library 100 STYX 31817274 Viruses 2019 PMC6950457 10.3390/v11121123 1 0 0 164 *Mimiviridae|Japan|Giant Viruses|Genome, Viral|Amoeba|Phylogeny 64 STYX 31657065 J. Anim. Breed. Genet. 2019 10.1111/jbg.12451 0 0 0 164 Pregnancy|Female|Animals|Rabbits|*Litter Size|Bayes Theorem|*Genome-Wide Association Study|*Phenotype|Breeding|Birth|*Genomics|Selection, Genetic|Ovulation|Genotype|Parity|Embryo, Mammalian|Uterus 64 STYX 31146910 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.05.093 0 2 0 164 Humans|*Tyrosine|*Threonine|*Serine|DNA Copy Number Variations|*Glioma|Glioblastoma|Brain Neoplasms|*Oncogenesis|Cell Proliferation|Gene Expression Regulation, Neoplastic|RNA, Micro|Cell Movement|Cell Line, Tumor|Xenograft Model Antitumor Assays|Oncogenes|*Phosphatases|Apoptosis|Astrocytes 64 STYX 30981757 Cancer Lett. 2019 10.1016/j.canlet.2019.04.014 2 7 0 164 Humans|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|*Colorectal Cancer|Epithelial-Mesenchymal Transition|HCT116 Cells|Cell Movement|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Proliferation|HT29 Cells|Cell Line, Tumor|Apoptosis|Oncogenes|Signal Transduction|*Colonic Neoplasms|STYX protein, human|Nuclear Proteins|Intracellular Signaling Peptides and Proteins 64 STYX 30909412 Int J Mol Sci 2019 PMC6470616 10.3390/ijms20061455 1 10 0 164 Humans|HDAC6 protein, human|*Histone Deacetylase 6|*Tubulin|*Phosphorylation|Acetylation|Microtubules|*Cytoplasm|Histone Deacetylases|Protein Processing, Post-Translational|Apoptosis Regulatory Proteins|Binding Protein|HeLa Cells|*Cytosol|Protein Binding|Signal Transduction|Cell Nucleus|STYX protein, human|Nuclear Proteins 64 SULF1 31878997 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2019 0 0 0 390 *Prognosis|*Colon Cancer|Gene Expression Profiling|*Bioinformatic|Kaplan-Meier Estimate|Macrophages|Gene Expression Regulation, Neoplastic|Sulfotransferases|Microarray Analysis|Sulfatases 231 SULF1 31773868 Neurogastroenterol. Motil. 2019 10.1111/nmo.13764 0 0 0 390 Humans|*RNA, Micro|*mRNA|*Esophageal Achalasia|Gene Expression Profiling|Gene Regulatory Networks 231 SULF1 31647919 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111685 0 0 0 390 Mice|Animals|*Cell Signaling|SULF2 protein, human|Sulfotransferases|Wnt Proteins|Cell Differentiation|Satellite Cells, Skeletal Muscle|Sulfatases|Muscle Development|*Aging|Heparitin Sulfate|Muscle, Skeletal|Receptor Protein-Tyrosine Kinases|Cells, Cultured 231 SULF1 31612481 J. Cell. Physiol. 2019 PMC6916361 10.1002/jcp.29067 2 0 0 390 Humans|*Transcriptional Network|*Adenocarcinoma|RNA, Micro|*Colonic Neoplasms|*Disease Progression|Gene Expression Regulation, Neoplastic|RNA, Long Noncoding|Gene Ontology|Gene Expression Profiling|Genes, Regulator|Computational Biology|Transcription Factors|RNA, Messenger|Biomarkers, Tumor|Colon|CTHRC1 protein, human|Extracellular Matrix Proteins 231 SULF1 31461325 Am. J. Physiol. Lung Cell Mol. Physiol. 2019 PMC6879902 10.1152/ajplung.00175.2019 1 0 0 390 Humans|Mice|Animals|Endothelial Cells|Glycocalyx|*Endothelium|*Lung|*Sepsis|Heparitin Sulfate|Lung Injury|Lipopolysaccharides|Neutrophils|Signal Transduction|Leukocytes|Sulfatases 231 SULF1 31434553 Circ. Res. 2019 10.1161/CIRCRESAHA.119.315023 3 1 0 390 Animals|Mice|*Vascular Endothelial Growth Factor A|*Biological Availability|*Heparitin Sulfate|Sulfatases|*N-Acetylgalactosamine-4-Sulfatase|Sulfotransferases|Signal Transduction|Cells, Cultured|Mice, Inbred C57BL 231 SULF1 31428635 Biomed Res Int 2019 PMC6679890 10.1155/2019/4508048 0 0 0 390 Mice|Animals|*Zebrafish|*Glomerular Filtration Barrier|Endothelial Cells|Zebrafish Proteins|Podocyte|Pronephros|Morpholinos|Gene Expression Regulation, Developmental|Gene Knockdown Techniques|Basement Membrane, Glomerular|*N-Acetylgalactosamine-4-Sulfatase|Larvae|Phenotype|Signal Transduction|Sulf1 protein, mouse|Sulfotransferases 231 SULF1 31346255 J Hum Hypertens 2019 10.1038/s41371-019-0218-7 2 1 0 390 Humans|*DNA Methylation|*Histone Code|*Blood Pressure|Epigenesis, Genetic|Hypertension|*Blood Pressure Determination|Epigenetic|Histones|*Protein Processing, Post-Translational|Risk Factor|Cardiovascular Disease|Systole 231 SULF1 31218106 Am J Cancer Res 2019 PMC6556596 0 0 0 390 Humans|Female|*Cisplatin|*CRISPR-Cas Systems|Early Detection of Cancer|*CRISPR|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Cell Lines|Gene Library|Drug Resistance, Neoplasm|Genome, Human|Genome-Wide Association Study|Bioinformatic|SULF1 protein, human|Sulfotransferases 231 SULF2 31701075 Hepatol Commun 2019 PMC6824075 10.1002/hep4.1429 0 0 0 302 Carcinoma, Hepatocellular|Liver Neoplasms|*Autophagy|Lysosomes|Autophagosomes|Viability, Cell|Cell Proliferation|Apoptosis|Cell Line, Tumor|RNA Silencing|Signal Transduction|Intracellular Membranes|Cell Cycle|Sulfatases 169 SULF2 31647919 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111685 0 0 0 302 Mice|Animals|*Cell Signaling|SULF2 protein, human|Sulfotransferases|Wnt Proteins|Cell Differentiation|Satellite Cells, Skeletal Muscle|Sulfatases|Muscle Development|*Aging|Heparitin Sulfate|Muscle, Skeletal|Receptor Protein-Tyrosine Kinases|Cells, Cultured 169 SULF2 31499680 Math Biosci Eng 2019 10.3934/mbe.2019231 1 0 0 302 *Carcinoma, Non-Small-Cell Lung|*Epithelial-Mesenchymal Transition|*Lung Neoplasms|*Downregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|3' Untranslated Regions|Cell Line, Tumor|Cell Proliferation|Transforming Growth Factor beta|SULF2 protein, human|*Sulfotransferases|Signal Transduction 169 SULF2 31434553 Circ. Res. 2019 10.1161/CIRCRESAHA.119.315023 3 1 0 302 Animals|Mice|*Vascular Endothelial Growth Factor A|*Biological Availability|*Heparitin Sulfate|Sulfatases|*N-Acetylgalactosamine-4-Sulfatase|Sulfotransferases|Signal Transduction|Cells, Cultured|Mice, Inbred C57BL 169 SULF2 31204561 Cell Cycle 2019 PMC6649599 10.1080/15384101.2019.1632135 3 5 0 302 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|MicroRNAs|*Signal Transduction|*Genes, Tumor Suppressor|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|A549 Cells|Cell Movement|RNA Interference|Cell Line, Tumor|SULF2 protein, human|*Sulfotransferases|Cell Proliferation|Transforming Growth Factor beta1|3' Untranslated Regions 169 SULF2 30980466 Glia 2019 PMC6617735 10.1002/glia.23621 1 1 0 302 Animals|Mice|*Astrocytes|OLIG2 protein, human|*Oligodendrocyte Transcription Factor 2|*Spinal Cord|*Sulfatases|Neurogenesis|Oligodendrocyte Precursor Cells|Oligodendroglia|Neural Stem Cells|Cell Differentiation|Motor Neurons|Hedgehog Proteins|SULF2 protein, human|Sulfotransferases|Glial Cell|Nerve Tissue Proteins|Transcription Factor|Olig2 protein, mouse 169 SULF2 30924907 Histol. Histopathol. 2019 PMC6742574 10.14670/HH-18-107 0 2 0 302 Humans|Mice|Animals|*Intervertebral Disk|Intervertebral Disc Degeneration|*Heparitin Sulfate|Anulus Fibrosus|Nucleus Pulposus|Type II Collagen|Mice, Knockout|*Homeostasis|Signal Transduction|Sulfotransferases|Heparan Sulfate Proteoglycan|Collagen 169 SULF2 30788513 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03027-2 3 0 0 302 Animals|Humans|HEK293 Cells|*Heparitin Sulfate|SULF2 protein, human|*Sulfotransferases|*Sulfatases|Recombinant Proteins|Substrate Specificity|Protein Binding 169 SULF2 30755594 Exp. Mol. Med. 2019 PMC6372678 10.1038/s12276-019-0207-5 1 46 0 302 superoxide dismutase 2|*Superoxide Dismutase|Reactive Oxygen Species|Mitochondria|Oxidative Stress|Signal Transduction|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|Apoptosis|Neoplasm Invasiveness 169 SULF2 30698737 Nucleic Acids Res. 2019 PMC6468246 10.1093/nar/gkz041 5 3 0 302 Humans|*Vascular Endothelial Growth Factor A|*Tumor Microenvironment|SULF2 protein, human|*Sulfotransferases|TRF2 Protein|Cell Line, Tumor|Neovascularization, Pathologic|Cell Proliferation|Colonic Neoplasms|Gene Expression Regulation, Neoplastic|Cell Movement|Colorectal Cancer 169 SULF2 30687385 Front Genet 2019 PMC6334744 10.3389/fgene.2018.00699 4 0 0 302 Sheep|Animals|*Genome|Genotype|Phenotype|Sheep, Domestic|Breeding|Polymorphism, Single Nucleotide|Livestock|Ethiopia|Middle East|Africa, Southern|Europe|China|Caribbean 169 SVOP 31460783 J. Comput. Biol. 2019 10.1089/cmb.2019.0125 0 0 0 115 *Glioblastoma|*DNA Methylation|*Prognosis|Neoplasm Recurrence, Local|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Regulatory Networks|Gene Expression Profiling|Databases, Genetic|Survival Analysis 26 SWAP70 31444835 Cancer Sci. 2019 PMC6778633 10.1111/cas.14177 1 0 0 162 Humans|ALK protein, human|*Anaplastic Lymphoma Kinase|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|ErbB Receptors|*Chinese|Oncogene Proteins, Fusion|Gene Rearrangement|Sequencing, Next-Generation|Mutation 81 SWAP70 31134483 Funct. Integr. Genomics 2019 10.1007/s10142-019-00689-w 0 0 0 162 Animals|Swine|*miRNAs|*Classical Swine Fever Virus|*Classical Swine Fever|Leukocytes, Mononuclear|Gene Expression Profiling|Transcriptome|Gene Regulatory Networks|RNA, Messenger 81 SWAP70 31126858 Vaccine 2019 PMC7087478 10.1016/j.vaccine.2019.05.024 2 2 0 162 Humans|Female|Mice|Animals|*Mammary Neoplasms, Animal|*Antigens, Neoplasm|Cancer Vaccines|Receptor, ErbB-2|Mice, Transgenic|Mammary Neoplasms, Experimental|Triple-Negative Breast Cancer|SWAP70 protein, human|DNA-Binding Proteins|Nuclear Proteins|Minor Histocompatibility Antigens|Guanine Nucleotide Exchange Factors|Swap70 protein, mouse 81 SWAP70 30922224 BMC Genomics 2019 PMC6438004 10.1186/s12864-019-5625-1 3 0 0 162 Animals|*Marek Disease|*RNA, Long Noncoding|*mRNA|*Spleen|Chickens|Herpesvirus 2, Gallid|Mardivirus|Gene Expression Profiling|Splenic Neoplasms|Cancers 81 SWAP70 30636036 FEBS Lett. 2019 10.1002/1873-3468.13326 0 2 0 162 *Cell Movement|Actin Cytoskeleton|Guanine Nucleotide Exchange Factors|Nuclear Proteins|DNA-Binding Proteins|rac1 GTP-Binding Protein|Actins|Minor Histocompatibility Antigens|Phosphatidylinositol Phosphates|Signal Transduction|*Molecular Conformation|Protein Binding 81 synpo 31720875 AMB Express 2019 PMC6854189 10.1186/s13568-019-0909-z 1 0 0 489 resazurin|*Nanofibers|*Xanthenes|*Oxazines|*Anti-Infective Agents|*Anti-Bacterial Agents|Escherichia coli|*Biological Assay 231 synpo 31677370 Acta Pharm 2019 10.2478/acph-2020-0011 0 0 0 489 Polyglycolic Acid|Lactic Acid|Polylactic Acid-Polyglycolic Acid Copolymer|poly(lactide)|Polyesters|Drug Carriers|Nanoparticles|Microspheres|Release, Drug|Molecular Weight|Particle Size|Hydrophobicity 231 synpo 31597702 J. Biol. Chem. 2019 PMC6873182 10.1074/jbc.RA119.009589 0 1 0 489 WWC1 protein, human|*Phosphoproteins|*Intracellular Signaling Peptides and Proteins|Protein Structure, Tertiary|Amino Acid Motifs|SYNPO protein, human|*Microfilament Proteins|Amino Acid Sequence|WW Domains|*Biophysical Phenomena|*Amino Acids|Models, Molecular|Tryptophan|*Brain 231 synpo 31417359 Front Cell Neurosci 2019 PMC6682679 10.3389/fncel.2019.00318 0 0 0 489 Mice|Animals|*Axon Initial Segment|*Retinal Ganglion Cells|SYNPO protein, human|*Microfilament Proteins|Axons|Pyramidal Neurons|Potential, Action|Spectrin|Ankyrins|Organelle|Mice, Inbred C57BL|Visual Cortex 231 synpo 31371487 J. Cell. Sci. 2019 PMC6737913 10.1242/jcs.230177 1 0 0 489 MYO5A protein, human|*Myosin Type V|*Myosin B|*Hippocampus|SYNPO protein, human|*Microfilament Proteins|*Neurons|Dendritic Spines|Dendrites|*Myosin Heavy Chains|Neuronal Plasticity|Synapses|Actins|Pyramidal Neurons|*Clustering 231 synpo 31254375 Mol Genet Genomic Med 2019 PMC6687626 10.1002/mgg3.786 1 0 0 489 *DNA Copy Number Variations|*Autism Spectrum Disorder|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide 231 synpo 31141397 Am. J. Physiol. Renal Physiol. 2019 10.1152/ajprenal.00406.2018 0 0 0 489 Mice|Animals|*Kidney Glomerulus|SMAD3 protein, human|*Smad3 Protein|*Glomerulonephritis|*Kidney Diseases|Podocytes|Proteinuria|Kidney|Signal Transduction|Transforming Growth Factor beta|Fibrosis|Disease Models, Animal 231 synpo 31127093 Cell Death Dis 2019 PMC6534572 10.1038/s41419-019-1625-y 1 5 0 489 Mice|Animals|*Podocytes|*Calcineurin|*NFATC Transcription Factors|PLAUR protein, human|Receptor, Urokinase Plasminogen Activator|*Signal Transduction|Proteinuria|Downregulation|*Protective Agents|Upregulation|Kidney Diseases|Lipopolysaccharides|Cells, Cultured|MicroRNAs 231 synpo 30872324 J. Neurosci. 2019 PMC6520517 10.1523/JNEUROSCI.2920-18.2019 0 1 0 489 Male|Female|Animals|Mice|*Alzheimer Disease|Hippocampus|*Disease Models, Animal|Presenilin-1|Ryanodine Receptor|SYNPO protein, human|*Microfilament Proteins|Amyloid Plaques|Calcium Signaling|Synapses 231 synpo 30744518 Autophagy 2019 PMC6613891 10.1080/15548627.2019.1580096 1 3 0 489 Humans|*Neurites|*Autophagy|SQSTM1 protein, human|Sequestosome-1 Protein|*tau Proteins|Autophagosomes|SYNPO protein, human|*Microfilament Proteins|Lysosomes|Apoptosis Regulatory Proteins|Neurons|Molecular Chaperones|Adaptor Proteins, Signal Transducing|Alzheimer Disease|Heat-Shock Proteins|Synapses|HeLa Cells|Phosphorylation 231 TARBP1 31349012 Clin. Immunol. 2019 10.1016/j.clim.2019.07.010 0 1 0 41 Humans|*Sjogren's Syndrome|Republic of Korea|*Study, Genetic Association|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Inflammation 26 TARBP1 31019095 RNA 2019 PMC6573781 10.1261/rna.070243.118 2 6 0 41 Humans|tRNA Methyltransferases|RNA, Bacterial|RNA, Transfer|TLR7 Receptor|Thermus thermophilus|Guanosine|Methylation|Innate Immune Responses|Escherichia coli 26 TBPL1 31879343 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6969503 10.1073/pnas.1912109117 0 0 0 1191 Mice|Humans|Animals|*CLOCK Protein|*Circadian Clocks|Bleomycin|Myofibroblast|Idiopathic Pulmonary Fibrosis|Lung|Fibroblasts|Cell Differentiation|Fibrosis|Mesenchymal Stem Cells|Gene Expression Regulation|Mice, Inbred C57BL|Cells, Cultured|TBPL1 protein, human|TATA Box Binding Protein-Like Proteins 28 TBPL1 31339356 Am. J. Respir. Crit. Care Med. 2019 PMC6884045 10.1164/rccm.201903-0511OC 4 1 0 1191 28 TBX2 31870844 Cancer Genet 2019 10.1016/j.cancergen.2019.12.001 0 0 0 496 339 TBX2 31870435 Respir. Res. 2019 PMC6929292 10.1186/s12931-019-1264-y 0 0 0 496 339 TBX2 31836586 Cold Spring Harb Mol Case Stud 2019 PMC6913154 10.1101/mcs.a004176 0 0 0 496 339 TBX2 31819055 Nat Commun 2019 PMC6901540 10.1038/s41467-019-13515-5 0 2 0 496 339 TBX2 31803947 Allergy 2019 PMC7216982 10.1111/all.14141 1 0 0 496 Humans|*Latent Class Analysis|*Anti-Inflammatory Agents, Non-Steroidal|Asthma, Aspirin-Induced|*Respiration Disorders|Aspirin|Asthma|Sputum, Induced|Eicosanoids|Phenotype 339 TBX2 31581124 Eur. J. Endocrinol. 2019 10.1530/EJE-19-0194 3 0 0 496 *ACTH-Secreting Pituitary Adenoma|*Transcriptome|Cushing Disease|Adenoma|Pituitary Neoplasms|Ubiquitin Thiolesterase|*Mutations|Endosomal Sorting Complexes Required for Transport|Endopeptidases|Corticotroph|Adrenocorticotropic Hormone|Pituitary Gland|*Microarray Analysis 339 TBX2 31580082 J. Proteome Res. 2019 10.1021/acs.jproteome.9b00396 0 3 0 496 Humans|Male|Female|Animals|*Y-Chromosome Gene|*Chromosomes, Human, Y|Pluripotent Stem Cells|Embryonic Stem Cells|Induced Pluripotent Stem Cells|Cell Differentiation|Signal Transduction|Embryo Development|Cells, Cultured 339 TBX2 31271353 Elife 2019 PMC6634974 10.7554/eLife.45274 1 3 0 496 Animals|*Transcription Factors|Drosophila Proteins|Drosophila|*Brain|Drosophila melanogaster|Neurogenesis|Cell Lineage|Gene Expression Regulation, Developmental|Neurons|Stem Cells|Cell Differentiation|Cell Proliferation|Nuclear Proteins 339 TBX2 31253870 Oncogene 2019 PMC6677575 10.1038/s41388-019-0853-z 0 4 0 496 heterochromatin-specific nonhistone chromosomal protein HP-1|*Chromosomal Proteins, Non-Histone|N-myc downstream-regulated gene 1 protein|Cell Cycle Proteins|*Promoter Regions, Genetic|Chromatin|Transcription Factor|Chromatin Immunoprecipitation|Intracellular Signaling Peptides and Proteins|Repressor Proteins|Transcription, Genetic|DNA-Binding Proteins|Histones|Tripartite Motif-Containing Protein 28|EZH2 protein, human|Enhancer of Zeste Homolog 2 Protein|siRNA|Gene Expression Regulation, Neoplastic 339 TBX2 31204702 J. Genet. 2019 1 0 0 496 Humans|*DiGeorge Syndrome|Comparative Genomic Hybridization|DNA Copy Number Variations|*Genetic Profile|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Marfan Syndrome|*Craniosynostoses|Chromosome Deletion|Heart Defects, Congenital|In Situ Hybridization, Fluorescence|Phenotypes|*Referral 339 TBX20 31548928 J Biol Res (Thessalon) 2019 PMC6751895 10.1186/s40709-019-0099-5 0 1 0 264 Osteogenesis|Mesenchymal Stem Cells|Cell Differentiation|Adipose Tissue|Transcription Factors|Cells, Cultured 167 TBX20 31524541 Genet Test Mol Biomarkers 2019 10.1089/gtmb.2019.0029 0 0 0 264 167 TBX20 31484864 Int Heart J 2019 10.1536/ihj.18-685 0 0 0 264 Infant|Humans|*Double Outlet Right Ventricle|*Mutation|Heterozygote|Congenital Heart Defects|Ventricular Septal Defect|Transcription Factor|Pedigree|Phenotype|Exons|*Disease Susceptibility|*Genotype|TBX20 protein, human|T-Box Domain Proteins 167 TBX20 31387875 eNeuro 2019 PMC6712207 10.1523/ENEURO.0022-19.2019 3 2 0 264 Mice|Animals|*Transcriptome|melanopsin|Rod Opsins|*Photoreceptor Cells|Retinal Ganglion Cells|*Ganglia|Vision|Circadian Rhythm|Light 167 TBX20 31372457 Data Brief 2019 PMC6660590 10.1016/j.dib.2019.103812 0 0 0 264 DNA Methylation|CpG Islands|*Regulatory Sequences, Nucleic Acid|*Atherosclerosis|Promoter Regions, Genetic|Epigenetic|Chromatin|Aorta|Genome|Myocytes, Smooth Muscle 167 TBX20 31299230 Dev. Biol. 2019 10.1016/j.ydbio.2019.05.012 0 0 0 264 Animals|Drosophila Proteins|Drosophila|*Signal Transduction|Imaginal Discs|Drosophila melanogaster|Body Patterning|Wnt1 Protein|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Genes, Insect|Transcription Factors|Extremities|dpp protein, Drosophila 167 TBX20 31205684 Cell Regen 2019 PMC6557755 10.1016/j.cr.2018.11.002 6 0 0 264 Humans|*Myocytes, Cardiac|Cell Cycle|Cyclins|Cyclin-Dependent Kinases|Signal Transduction|Cyclin-Dependent Kinase Inhibitor p27|Cyclin-Dependent Kinase Inhibitor p21|Proto-Oncogene Proteins c-akt|Retinoblastoma Protein|Phosphatidylinositol 3-Kinases|Transcription Factors|Cell Proliferation|IGF1 protein, human|IGF-1|Cell Division|Transcriptional Activation|Cyclin A|TBX20 protein, human 167 TBX20 31204705 J. Genet. 2019 0 3 0 264 Humans|*Alleles|*Heart Defects, Congenital|*Heart|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Genotype|T-Box Domain Proteins|Phenotype|Transcription, Genetic|Mutation 167 TBX20 31187911 Cell Biol. Int. 2019 10.1002/cbin.11192 0 0 0 264 Animals|Mice|*Transcription Factors|*Animals, Newborn|*Proteomics|Regeneration|*Gene Expression Profiling|Myocytes, Cardiac|Myocardium|Myocardial Infarction|Gene Expression Regulation, Developmental|Signal Transduction|Transcriptome 167 TBX20 31159871 Stem Cell Res Ther 2019 PMC6547465 10.1186/s13287-019-1263-4 1 1 0 264 Humans|*Mesenchymal Stem Cells|*Transcription Factor Oct-4|*Bone Marrow|Bone Marrow Cells|Cell Differentiation|Cells, Cultured|Cell Proliferation 167 TBX20 31138201 BMC Med Genomics 2019 PMC6540552 10.1186/s12920-019-0534-3 0 9 0 264 Humans|*Tetralogy of Fallot|*DNA Methylation|Epigenesis, Genetic|*B-DNA|CpG Islands|Promoter Regions, Genetic|Transcription Factors|Myocardium|RNA, Messenger|TBX20 protein, human|T-Box Domain Proteins 167 TBX20 31030447 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.05.025 0 0 0 264 Humans|*Cardiovascular Diseases|Brachyury protein|T-Box Domain Proteins|Atrial Septal Defect|Heart Defects, Congenital|Pedigree|Mutation|Mutation, Missense|Fetal Proteins|TBX20 protein, human 167 TBX20 30955100 Pediatr Cardiol 2019 10.1007/s00246-019-02099-y 0 0 0 264 Infant|Humans|*Heart Septal Defects, Ventricular|*Alternative Splicing|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|GATA4 Transcription Factor|Repressor Proteins|*Protein Isoforms|Congenital Heart Defects|Mutation|DNA|Heart|*Diploidy|TBX20 protein, human|T-Box Domain Proteins|HEY2 protein, human 167 TBX20 30859393 Drug Deliv Transl Res 2019 10.1007/s13346-019-00628-z 1 0 0 264 Sheep|Animals|*HMGB1 Protein|*Myocardial Infarction|Left Ventricular Function|Myocardium|Cardiomyocytes|Proto-Oncogene Proteins c-kit 167 TBX20 30820038 Eur. J. Hum. Genet. 2019 PMC6777542 10.1038/s41431-019-0364-y 0 0 0 264 Humans|Bicuspid Aortic Valve|*DNA Copy Number Variations|*Heart Valve Diseases|*Aortic Valve|Thoracic Aortic Aneurysms|Congenital Heart Defect|Phenotype|Gene Expression Regulation|TBX20 protein, human|T-Box Domain Proteins 167 TBX22 31596367 J Appl Oral Sci 2019 PMC6768118 10.1590/1678-7757-2018-0649 0 2 0 28 Mice|Animals|*Cleft Palate|*DNA Methylation|*B-DNA|*Palate|*Transcription Factors|Mice, Inbred C57BL|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Phenotype|Disease Models, Animal|RNA, Messenger|Fgf16 protein, mouse|Fibroblast Growth Factors 52 TBX22 31241704 An. Acad. Bras. Cienc. 2019 10.1590/0001-3765201920180945 0 1 0 28 Female|Pregnancy|Mice|Animals|Cleft palate X-linked|*Cleft Palate|*Methylation|*C57BL Mice|*Exon|Genetic Diseases, X-Linked|Palate|*Transcription Factors|T-Box Domain Proteins|Phenotype|Gene Expression|Pedigree|Gene Expression Regulation, Developmental|Amino Acid Sequence|Tretinoin|Mutation 52 TBX22 31150594 J. Dent. Res. 2019 PMC6651766 10.1177/0022034519851786 1 2 0 28 Humans|Mice|Animals|Cleft Soft Palate|Cleft Palate|Cleft Lip|Palate, Soft|Signal Transduction|Lip|Transcription Factors|Myogenesis|Gene Expression Regulation, Developmental 52 TBX22 30923412 Acta Histochem Cytochem 2019 PMC6434314 10.1267/ahc.18038 0 36 0 28 Animals|Chick Embryo|*Wnt Signaling Pathway|*Maxilla|Morphogenesis|Wnt Proteins|Gene Expression Regulation, Developmental|Cleft Palate|Transcription Factors|Cleft Lip|Face|Downregulation 52 TBX4 31872757 Environ. Sci. Technol. 2019 10.1021/acs.est.9b04674 1 0 0 115 Pregnancy|Humans|Female|Mice|Animals|Adult|*Maternal Exposure|Particulate Matter|Air Pollutants|Prenatal Exposure Delayed Effects 169 TBX4 31836586 Cold Spring Harb Mol Case Stud 2019 PMC6913154 10.1101/mcs.a004176 0 0 0 115 Humans|Female|Filamins|*Reading Frames|Pedigree|Abnormalities, Multiple|Mutation|Knee Dislocation|Clubfeet|Joint Laxity 169 TBX4 31761294 Am. J. Hum. Genet. 2019 PMC6904794 10.1016/j.ajhg.2019.10.013 1 3 0 115 Humans|Animals|Ischiopatellar dysplasia|Bone Diseases, Developmental|*Mutations|Ischium|*Homozygote|Hip|*Null Mutations|Patella|*Pelvis|Pedigree|T-Box Domain Proteins|*Respiratory System Abnormalities|Phenotype|Syndrome|TBX4 protein, human 169 TBX4 31754465 EFORT Open Rev 2019 PMC6836073 10.1302/2058-5241.4.190006 0 0 0 115 Humans|Female|*Hip Dislocation, Congenital|Genetic Predisposition to Disease|Asian|Polymorphism, Single Nucleotide|Acetabulum|Case-Control Studies|CCN6 protein, human|CCN Intercellular Signaling Proteins|HOXB9 protein, human|Homeodomain Proteins|UQCC protein, human|Membrane Proteins 169 TBX4 31727138 Genome Med 2019 PMC6857288 10.1186/s13073-019-0685-z 4 1 0 115 Humans|*Pulmonary Arterial Hypertension|*Exome|*Familial Primary Pulmonary Hypertension|*Whole Exome Sequencing|BMPR2 protein, human|Bone Morphogenetic Protein Receptor Type II|Hypertension, Pulmonary|Mutations|Genetic Predisposition to Disease|*Risk Factors 169 TBX4 31641660 Autops Case Rep 2019 PMC6771452 10.4322/acr.2019.119 0 0 0 115 Infant, Newborn|Humans|Female|Pregnancy|Lung Diseases|Lung|*Respiratory System Abnormalities|Respiratory Insufficiency|T-Box Domain Proteins|Infant, Newborn, Diseases 169 TBX4 31503387 J Tissue Eng Regen Med 2019 PMC6992527 10.1002/term.2961 0 0 0 115 Adult|Humans|Infant, Newborn|*RNA, Long Noncoding|*Transcriptome|*Transcription Factors|*Mesenchymal Stem Cells|Chondrogenesis|Articular Cartilage|Osteoarthritis|Gene Expression Profiling|Cell Differentiation 169 TBX4 31406341 Nat Rev Cardiol 2019 10.1038/s41569-019-0242-x 6 0 0 115 *Pulmonary Arterial Hypertension|BMPR2 protein, human|Bone Morphogenetic Protein Receptors, Type II|*Familial Primary Pulmonary Hypertension|Artery, Pulmonary|Hypertension, Pulmonary|Smooth Muscle Cells|Genetic Predisposition to Disease|Heredity|Phenotype|Mutation 169 tbxt 31475743 Anim. Genet. 2019 PMC6899607 10.1111/age.12852 0 0 0 369 Sheep|Animals|Brachyury protein|Iran|*Fetal Proteins|*T-Box Domain Proteins|*Phenotype|Genotypes|Allele|Exon|Breeding|Base Sequence|Mutation|Amino Acid Sequence|Missense Mutation|Polymorphism, Single Nucleotide 75 tbxt 31429169 Mol. Reprod. Dev. 2019 10.1002/mrd.23257 0 0 0 369 Mice|Cats|Animals|*Transcription Factors|Glycogen Synthase Kinase 3|Induced Pluripotent Stem Cells|*Fibroblasts|Cellular Reprogramming|POU5F1 protein, human|Octamer Transcription Factor-3|Embryoid Bodies|Cell Differentiation|*Felis|*Fetus|Cells, Cultured|Kruppel-Like Transcription Factors|Embryo, Mammalian|SOXB1 Transcription Factors|Transgenes|*Complement Factor B|3'-(1-butylphosphoryl)adenosine 75 tbxt 31399472 Development 2019 PMC6737904 10.1242/dev.175604 0 5 0 369 Humans|*Neural Crest|*Human Embryonic Stem Cell|Pluripotent Stem Cells|Cell Differentiation|Cell Lineage|beta Catenin|Wnt Signaling Pathway|*Catenins|Gene Expression Regulation, Developmental|Fibroblast Growth Factors 75 tbxt 31221659 Dis Model Mech 2019 PMC6679381 10.1242/dmm.039545 0 0 0 369 Animals|*Chordoma|*Zebrafish|Brachyury protein|*Fetal Proteins|*T-Box Domain Proteins|Notochord|Oncogenesis|Tyrosine 75 tbxt 31112700 Dev. Cell 2019 PMC6599594 10.1016/j.devcel.2019.04.019 0 0 0 369 Animals|*Xenopus laevis|*Morpholinos|Xenopus Proteins|*Embryogenesis|Oligonucleotides, Anti-Sense|Gene Expression Regulation, Developmental|Knockdowns, Gene|Brachyury protein|T-Box Domain Proteins|RNA Splicing|*Innate Immune Response|Fetal Proteins 75 tbxt 30664779 Nat. Med. 2019 PMC6633917 10.1038/s41591-018-0312-3 5 6 0 369 Brachyury protein|*Chordoma|*Transcription Factor|*Fetal Proteins|*T-Box Domain Proteins|Notochord|Cell Line, Tumor|Bone Neoplasms|Cell Proliferation|*Gene Expression Regulation 75 TCF15 30912256 Dev Neurobiol 2019 PMC6586502 10.1002/dneu.22676 1 0 0 58 Animals|*Hydra|*Neurogenesis|Stem Cells|Nervous System|Neurons|*Aging|Cell Differentiation|Gametogenesis|arginylphenylalaninamide|Neuropeptides|Epithelial Cells|Regeneration|Germ Cells|Hym-355 neuropeptide|Downregulation 39 TDRD3 31400491 Int. J. Dev. Neurosci. 2019 PMC6897302 10.1016/j.ijdevneu.2019.07.011 0 2 0 132 Pregnancy|Humans|Mice|Female|Animals|Male|*Androgens|AR protein, human|Androgen Receptor|*Hippocampus|CYP19A1 protein, human|Aromatase|Testosterone Propionate|Dihydrotestosterone|Sex Differences|Receptors, Estrogen|mRNA|Orchiectomy|Cerebral Cortex|RNA-Binding Motifs 25 TDRD3 31125834 Comp. Biochem. Physiol. Part D Genomics Proteomics 2019 10.1016/j.cbd.2019.05.003 0 0 0 132 Female|Male|Animals|*Flounder|Phylogeny|Japan|Evolution, Molecular|Synteny|Gonads|Genome|Sex Differentiation|Testis|Fish Proteins|Sequence Alignment|Spermatogenesis|Amino Acid Sequence|Ovary|Tudor Domain|Sexual Dimorphisms 25 TEN1 31396577 Commun Biol 2019 PMC6686008 10.1038/s42003-019-0546-8 0 1 0 78 Yeast, Fission|Schizosaccharomyces pombe Proteins|Telomere-Binding Proteins|Telomere|Telomere Homeostasis|Telomerase|Carrier Proteins|Protein Binding|Sumoylation|Mutation|Tpz1 protein, S pombe 122 TEN1 31245382 Front Mol Biosci 2019 PMC6581698 10.3389/fmolb.2019.00041 2 1 0 78 Humans|Telomere-Binding Proteins|Telomere|Telomere Homeostasis|Telomerase|DNA Polymerase I|Chromosomal Proteins, Non-Histone|DNA Replication|Mutations|Protein Structure, Secondary|Ten1 protein, human|Stn1 protein, human 122 TEN1 31130838 Front Neurosci 2019 PMC6510184 10.3389/fnins.2019.00425 0 0 0 78 Animals|alpha-latrotoxin receptor|Receptors, Peptide|Nerve Tissue Proteins|Tenascin|Amino Acid Sequence|Choanoflagellates|G-Protein-Coupled Receptors|Gene Transfer, Horizontal|Prokaryotic Cells 122 TEN1 31062447 J. Anim. Breed. Genet. 2019 10.1111/jbg.12403 2 0 0 78 Animals|Cattle|*Altitude|*Genome|Natural Selection|SNPs|Base Sequence|Acclimatization|Gene Ontology|Adaptation, Physiological|Tibet 122 TEN1 31028137 Biosci. Rep. 2019 PMC6522806 10.1042/BSR20190312 1 0 0 78 *Polymorphism, Single Nucleotide|Telomere-Binding Proteins|Telomere Homeostasis|Telomere|DNA Replication|Protein Binding|Mutations|Genomics 122 TEN1 31006804 Nucleic Acids Res. 2019 PMC6614848 10.1093/nar/gkz279 1 1 0 78 *Telomeres|*RNA Polymerase II|Telomere-Binding Proteins|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Chromosomal Proteins, Non-Histone|Cell Cycle Proteins|Telomerase|S Phase|Protein Binding|Cdc13 protein, S cerevisiae|HMO1 protein, S cerevisiae|High Mobility Group Proteins|TEN1 protein, S cerevisiae 122 TEN1 30979824 Life Sci Alliance 2019 PMC6464128 10.26508/lsa.201800270 0 50 0 78 Humans|*Chromatin|Ctc1 protein, human|*Telomere-Binding Proteins|Telomere|DNA Replication|DNA Polymerase I|Replication Origins|DNA Primase|Telomerase|S Phase|Cell Cycle Proteins|HeLa Cells|Ten1 protein, human|Stn1 protein, human 122 TEN1 30976812 Nucleic Acids Res. 2019 PMC6547417 10.1093/nar/gkz264 3 2 0 78 Humans|Animals|*G-Quadruplexes|Telomere|Telomere-Binding Proteins|Telomerase|DNA Replication|DNA Polymerase I|DNA, Single-Stranded|DNA|HeLa Cells|Protein Binding|*Mammals|Ten1 protein, human|Stn1 protein, human 122 TEN1 30796050 EMBO J. 2019 PMC6443209 10.15252/embj.2018100476 0 3 0 78 *Telomere|Ctc1 protein, human|Telomere-Binding Proteins|Yeast, Fission|*DNA Replication|Schizosaccharomyces pombe Proteins|Telomerase|Telomere Homeostasis|DNA Polymerases|Phosphorylation|*Phosphoric Monoester Hydrolases|Protein Binding 122 TENM3 31772663 J Cancer 2019 PMC6856753 10.7150/jca.33250 0 0 0 39 28 TENM3 31767573 eNeuro 2019 PMC6901682 10.1523/ENEURO.0478-18.2019 1 1 0 39 Animals|Mice|*Mice, Knockout|Geniculate Bodies|Visual Pathways|*Critical Period, Psychological|Superior Colliculi|Axons|Visual Cortex|Nerve Tissue Proteins|Retinal Ganglion Cells|Membrane Proteins|Retina 28 TENM3 31522852 J Arthroplasty 2019 10.1016/j.arth.2019.08.031 0 0 0 39 Humans|*Genetic Predisposition to Disease|*Hip Dislocation, Congenital|Polymorphism, Single Nucleotide|Gene Frequency|Alleles|Asian Continental Ancestry Group 28 TENM3 31241739 Carcinogenesis 2019 10.1093/carcin/bgz112 0 0 0 39 Humans|*Urothelium|*DNA Methylation|Carcinoma, Transitional Cell|CpG Islands|Urologic Neoplasms|Urinary Bladder Neoplasms|Epigenesis, Genetic|Genome-Wide Association Study|Biomarkers, Tumor|Receiver Operating Characteristic|Sensitivity and Specificity 28 TESC 31601890 Sci Rep 2019 PMC6787090 10.1038/s41598-019-50507-3 1 0 0 122 Humans|Adult|*Genome-Wide Association Study|*Neurogenesis|*Hippocampus|Neurons|Alzheimer Disease|Cell Differentiation|Cognition|Cohort Studies|MSRB3 protein, human|Methionine Sulfoxide Reductases 66 TESC 31396938 Methods Mol. Biol. 2019 10.1007/978-1-4939-9728-2_15 0 0 0 122 Mice|Animals|*Epithelial Cells|Stem Cells|Cell Differentiation|T Cells 66 TESC 31309142 Sci Adv 2019 PMC6625822 10.1126/sciadv.aav5931 0 0 0 122 *Spectroscopy|Surface Plasmon Resonance|Nanotechnology|Nanostructures|Quantum Dots|Microscopy, Atomic Force 66 TESC 31002343 Oncol. Rep. 2019 10.3892/or.2019.7099 0 4 0 122 Humans|Mice|Animals|*Stomach Neoplasms|Epigenesis, Genetic|*Cell Survival|*Promoter Regions, Genetic|DNA Methylation|CpG Islands|*Stomach|5-AzadC|Azacitidine|Gene Silencing|Gene Expression Regulation, Neoplastic|Downregulation|*Protein Processing, Post-Translational|Histones|Cell Line, Tumor|Cell Proliferation 66 TEX14 31659914 FASEB J. 2019 PMC6894055 10.1096/fj.201901247R 0 0 0 73 Male|Mice|Female|Animals|Child|Humans|*Ovarian Follicle|Germ Cell|Meiosis|Oocytes|Ovary|RNA Binding Protein|Oogenesis|mRNA|Testis|Gene Expression Regulation, Developmental|Fertility|Short Interfering RNA|3' UTR|Fetus|Cell Differentiation|Knockout Mouse|DAZL protein, human|TEX14 protein, human 43 TEX14 31515857 J. Anim. Breed. Genet. 2019 10.1111/jbg.12438 0 0 0 73 Cattle|Male|Animals|*Genome-Wide Association Study|Sexual Maturation|Breeding|Phenotype|Linkage Disequilibrium|Quantitative Trait Loci|Genotype|Reproduction|Spermatogenesis|Genomics|Fertility|Polymorphism, Single Nucleotide 43 TEX14 31479588 Andrology 2019 10.1111/andr.12704 1 0 0 73 Humans|Male|*Infertility, Male|Azoospermia|Whole Exome Sequencing|Spermatogenesis|Genetic Predisposition to Disease|Sequencing, Next-Generation|Mutation|Testis 43 TEX14 31175093 Clin. Cancer Res. 2019 PMC6726519 10.1158/1078-0432.CCR-18-2423 0 0 0 73 Humans|Female|*DNA Methylation|Breast Cancer, Familial|*Breast Neoplasms|*Genetic Predisposition to Disease|hydrogen sulfite|Genes, BRCA1|CpG Islands|Genes, BRCA2|BRCA1 Protein|Promoter Regions, Genetic|Epigenesis, Genetic|Mutations|Ovarian Neoplasms 43 TEX14 31065688 J Mol Cell Biol 2019 PMC7052986 10.1093/jmcb/mjz035 1 1 0 73 Humans|Male|Mice|Animals|*Testis|*Aging, Premature|*Spermatogenesis|Transcription Factor IID|TATA-Binding Protein Associated Factors|Azoospermia|Transcription Factors|Spermatozoa|DNA-Binding Proteins|Transcription, Genetic|Fertility|BNC1 protein, human|Ybx2 protein, mouse|RNA-Binding Proteins|TAF7L protein, mouse|Odf1 protein, mouse|Heat-Shock Proteins|Bnc1 protein, mouse 43 TEX14 31022261 PLoS ONE 2019 PMC6483353 10.1371/journal.pone.0215913 7 0 0 73 Female|Pregnancy|Horses|Male|Animals|*Breeding|Haplotype|Homozygote|Genotype|Selection, Genetic|Genomes|*Sport|Phenotypes|Genomics|Polymorphism, Single Nucleotide|Fertility|Crossbreeding|Principal Component Analysis 43 TEX14 30719983 Asian J. 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Chem. 2019 PMC6463713 10.1074/jbc.RA118.006341 2 5 0 100 Humans|Mice|Animals|*Human Embryonic Stem Cells|*Transcription Factor|Mouse Embryonic Stem Cell|GKLF protein|Kruppel-Like Transcription Factors|Stem Cell Self-Renewal|LIF protein, human|Inhibitory Factor, Leukemia|Cell Differentiation|Pluripotent Stem Cells|*Gene Expression Regulation|Repressor Proteins|Wnt Signaling Pathway|Downregulation|Cell Line|Receptors, Estrogen 46 Tfcp2l1 30704470 BMC Med Genomics 2019 PMC6357449 10.1186/s12920-018-0467-2 2 0 0 100 Humans|*Glucocorticoids|*Transcriptome|NR3C1 protein, human|Glucocorticoid Receptor|*Cells, Epithelial|*Cell Lines|Adrenergic beta-2 Receptor Agonists|Asthma|Bronchi|Respiratory Mucosa|Transcription, Genetic|Corticosteroids 46 TFEC 31768316 Asian J Urol 2019 PMC6872788 10.1016/j.ajur.2019.04.003 0 0 0 72 *Carcinoma, Renal Cell|*Microphthalmos|Renal Neoplasms|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Translocation, Genetic|Transcription Factor Microphthalmia|In Situ Hybridization, Fluorescence|Oncogene Proteins, Fusion|Biomarkers, Tumor 93 TFEC 31252474 ACS Appl Mater Interfaces 2019 10.1021/acsami.9b05570 0 1 0 72 *Lithium|*Silicon|*Electric Power Supplies|*Anode|*Electrolytes|*Carbonates|*Sodium Chloride|*Sodium Chloride, Dietary|*Fluorination|*Solvents|vinyl fluoride|Vinyl Compounds|Nanoparticle 93 TFEC 31160892 Cell. 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Dis. Sci. 2019 10.1007/s10620-019-05825-x 2 1 0 1320 Mice|Animals|*Stomach|*Wound Healing|Stomach Ulcer|Gastric Mucosa|Ulcer|*Active Transport 484 TFF2 31481545 Gut 2019 PMC7282188 10.1136/gutjnl-2019-318930 1 0 0 1320 spasmolytic polypeptide|*Metaplasia|*Stomach|TFF2 protein, human|*Trefoil Factor-2|*Peptides|Gastric Mucosa|Parietal Cells, Gastric|Stomach Neoplasms|Precancerous Conditions|Helicobacter Infections|*Inflammation|Intercellular Signaling Peptides and Proteins|*Upper Gastrointestinal Tract|Adenocarcinoma 484 TFPI2 31608996 J. Cell. Physiol. 2019 10.1002/jcp.29304 0 0 0 737 Humans|*Risk Factors|RNA, Long Noncoding|Prognosis|Messenger RNA|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|MicroRNAs|Biomarkers, Tumor|Kaplan-Meier Estimate|Signal Transduction 125 TFPI2 31405379 Clin Epigenetics 2019 PMC6689875 10.1186/s13148-019-0715-0 2 0 0 737 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*DNA Methylation|Promoter Regions, Genetic|Head and Neck Neoplasms|Squamous Cell Carcinoma of Head and Neck|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Genes, Tumor Suppressor 125 TFPI2 31254429 Cancer Sci. 2019 PMC6726682 10.1111/cas.14118 5 0 0 737 Humans|Male|Dogs|Animals|*Urinary Bladder Neoplasms|*Organoids|Bladder|Cisplatin|Antineoplastic Agents|Piroxicam|Prostate Cancer|Disease Models, Animal|Viability, Cell 125 TFPI2 31186379 Aging (Albany NY) 2019 PMC6594811 10.18632/aging.102018 4 8 0 737 Humans|*RNA, Long Noncoding|*Glioblastoma|*Oncogenesis|*Epigenesis, Genetic|*Oncogenes|Cell Proliferation|Enhancer of Zeste Homolog 2 Protein|Gene Expression Regulation, Neoplastic|Up-Regulation|Cell Line, Tumor|Downregulation|tissue-factor-pathway inhibitor 2|*Glycoproteins|Cell Movement|Transcriptional Activation|Apoptosis|Disease Progression|Histone Demethylases 125 TFPI2 31097151 Mutat. Res. 2019 10.1016/j.mrrev.2019.01.003 2 1 0 737 Humans|*Colorectal Cancer|*Adenoma|*Feces|DNA Methylation|Early Detection of Cancer|Biomarkers, Tumor|BMP3 protein, human|Bone Morphogenetic Protein 3|*Colonic Neoplasms|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Membrane Proteins|Promoter Regions, Genetic|Sensitivity and Specificity|*DNA|tissue-factor-pathway inhibitor 2|Glycoproteins|SPG20 protein, human 125 TFPI2 31080560 Oncotarget 2019 PMC6499600 10.18632/oncotarget.26884 0 0 0 737 Humans|Female|*Epithelial-Mesenchymal Transition|*Endometrial Cancer|Acetylglucosamine|N-Acetylglucosaminyltransferases|Cell Proliferation|Cell Movement|Glycosylation|Protein Processing, Post-Translational|Cell Line, Tumor|*Endometrium 125 TFPI2 30651599 Oncogene 2019 PMC6756014 10.1038/s41388-018-0671-8 1 8 0 737 *Mixed Function Oxygenases|DNA Methylation|Epigenesis, Genetic|Promoter Regions, Genetic|tissue-factor-pathway inhibitor 2|*Glycoproteins|*Mono-ADP-Ribosylation|Epigenetics|Histone|Proto-Oncogene Proteins|Chromatin|Gene Expression Regulation, Neoplastic|DNA-Binding Proteins|Cell Proliferation|Colorectal Cancer|Demethylation|Genes, Tumor Suppressor 125 TGFBR3 31871122 Cancer Immunol Res 2019 10.1158/2326-6066.CIR-19-0574 4 0 0 438 CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Immunologic Memory|L-Selectin 627 TGFBR3 31835434 Int J Mol Sci 2019 PMC6941059 10.3390/ijms20246214 0 20 0 438 Rats|Animals|Male|betaglycan|*Phosphorylation|*Sertoli Cells|*Receptors, Transforming Growth Factor beta|*Proteoglycans|*Signal Transduction|SMAD2 protein, human|Smad2 Protein|*Protein Binding|Transforming Growth Factor beta|SMAD3 protein, human|Smad3 Protein|Receptor, Transforming Growth Factor-beta Type II|*Transforming Growth Factor|Protein-Serine-Threonine Kinases|Receptor, Transforming Growth Factor-beta Type I|Cell Line|Cell Proliferation 627 TGFBR3 31803141 Front Endocrinol (Lausanne) 2019 PMC6872544 10.3389/fendo.2019.00790 0 0 0 438 627 TGFBR3 31738999 J. Hepatol. 2019 10.1016/j.jhep.2019.10.029 1 1 0 438 Animals|*miRNA|Schistosoma japonicum Infection|betaglycan|*Receptors, Transforming Growth Factor beta|*Liver Cirrhosis|Schistosoma japonicum|*Schistosomatidae|Hepatic Stellate Cells|*Proteoglycans 627 TICRR 31275851 Front Oncol 2019 PMC6591320 10.3389/fonc.2019.00516 0 0 0 110 DNA Replication|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|DNA Damage|DNA-Binding Proteins|Tumor Suppressor Protein p53|Carrier Proteins|Signal Transduction|Phosphorylation|Apoptosis 29 TICRR 30695077 PLoS Biol. 2019 PMC6377148 10.1371/journal.pbio.2006767 3 21 0 110 Humans|Animals|CCNC protein, human|*Cyclin C|DNA Replication|Cell Cycle Proteins|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|DNA-Binding Proteins|Carrier Proteins|Nuclear Proteins|Protein Binding|Virus Replication|CDK8 protein, human|Cyclin-Dependent Kinase 8|MTBP protein, human|TICRR protein, human 29 TIMD4 31337960 Int J Med Sci 2019 PMC6643107 10.7150/ijms.31729 2 0 0 299 81 TIMD4 31019284 Nat. 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Immunol. 2019 PMC6733267 10.1038/s41577-019-0167-y 12 1 0 299 *Macrophages|Phagocytosis|axl receptor tyrosine kinase|Receptor Protein-Tyrosine Kinases|Serine, Phosphatidyl|c-Mer Tyrosine Kinase|Proto-Oncogene Proteins|Caspases|Phagocytes|Cell Membrane|Apoptosis|Signal Transduction 81 TIMD4 30900506 Autophagy 2019 PMC6844530 10.1080/15548627.2019.1596493 2 2 0 299 Mice|Animals|*Antigen Presentation|*Class II Major Histocompatibility Molecules|*Autophagy|Cross-Priming|Autophagy-Related Protein 5|Histocompatibility Antigens Class I|TYRP1 protein, human|*Membrane Glycoproteins|Dendritic Cells|CD8-Positive T-Lymphocytes|*CD36 Antigens|Endocytosis|IgA receptor|Atg5 protein, mouse 81 TIMD4 30730912 PLoS ONE 2019 PMC6366744 10.1371/journal.pone.0211146 0 1 0 299 Humans|*Rheumatoid Arthritis|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Haplotypes|Alleles|TYRP1 protein, human|Membrane Glycoproteins|Asian Continental Ancestry Group|Genotype|Autoimmune Diseases|Hepatitis A Virus Cellular Receptor 2|Case-Control Studies|Membrane Proteins 81 TIMD4 30670766 Sci Rep 2019 PMC6342996 10.1038/s41598-018-36449-2 3 3 0 299 Humans|Animals|*Ebola Virus|*Hemorrhagic Fever, Ebola|*Cell Adhesion|HAVCR1 protein, human|*Hepatitis A Virus Cellular Receptor 1|Virus Attachment|Receptors, Virus|*Virus|Virus Internalization|*Cell Adhesion Molecules|Serine, Phosphatidyl|Receptors, Cell Surface|Virus Physiological Phenomena|Membrane Glycoproteins|Vesiculovirus|Host-Pathogen Interactions|Glycoprotein|HEK293 Cells 81 TIMD4 30626692 J. 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Eng. 2019 10.1016/j.ymben.2019.12.006 0 0 0 1757 *Pentose Phosphate Pathway|Escherichia coli|Metabolic Engineering|*Formaldehyde|Gene Expression Regulation, Bacterial|Methanol|Bacillus|Alcohol Oxidoreductases|Bacterial Proteins|Promoter Regions, Genetic|Gene Expression|*Redox 270 TKT 31769880 J. Inherit. Metab. 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Med. 2019 10.1111/jcmm.14787 0 0 0 214 *Carcinoma, Hepatocellular|CTNNB1 protein, human|*beta Catenin|*Liver Neoplasms|*Binding Protein|AXIN2 protein, human|Axin Protein|Wnt Signaling Pathway|TCF Transcription Factors|CCND1 protein, human|Cyclin D1|Cell Movement|Wnt Proteins|beta-Catenin Destruction Complex|Cell Proliferation|Downregulation|Cell Line, Tumor|*Biological Process 102 TM4SF1 31598403 Am J Cancer Res 2019 PMC6780668 0 1 0 214 *Vaccines, DNA|HLA-A2|T-Lymphocytes, Cytotoxic|TM4SF1 protein, human|*Antigens, Surface|*Neoplasm Proteins|Cancer Vaccines|Epitopes, T-Lymphocyte|Antigens, Neoplasm|*Cellular Immunity|*Endoplasmic Reticulum|Epitope, B-Cell|Immunotherapy|Cell Line, Tumor 102 TM4SF1 31498560 Cancer Med 2019 PMC6825983 10.1002/cam4.2544 1 0 0 214 Papillary Thyroid Microcarcinoma|*Epithelial-Mesenchymal Transition|*Carcinoma, Papillary|*Thyroid Neoplasms|Lymph Nodes|Lymphatic Metastasis|Thyroidectomy|Neck Dissection|*Lymphatic Vessels|Neck|Retrospective Studies|*Cancer Stem Cell|Risk 102 TM4SF1 31413629 Cancer Manag Res 2019 PMC6660099 10.2147/CMAR.S199027 0 1 0 214 102 TM4SF1 31213848 Onco Targets Ther 2019 PMC6549427 10.2147/OTT.S198140 3 0 0 214 102 TM4SF1 31142317 Respir. Res. 2019 PMC6542073 10.1186/s12931-019-1071-5 2 3 0 214 *Carcinoma, Non-Small-Cell Lung|*Proto-Oncogene Proteins c-akt|*Lung Cancer|MTOR protein, human|*TOR Serine-Threonine Kinases|A549 Cells|Phosphatidylinositol 3-Kinases|Cell Proliferation|Cell Movement|Neoplasm Invasiveness|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|*Neoplastic Processes 102 TM4SF1 31096305 Semin. Thromb. Hemost. 2019 10.1055/s-0039-1687908 1 0 0 214 Vascular Endothelial Growth Factor A|*Capillary Permeability|Endothelial Cells|*Wound Healing|*Blood Coagulation|*Tumors|Fibrin|Neovascularization, Pathologic|Vascular Endothelial Growth Factors|Blood Coagulation Factors|Inflammation|Plasma Proteins|Venules 102 TM4SF1 30876464 BMC Cancer 2019 PMC6419813 10.1186/s12885-019-5417-7 0 12 0 214 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Neoplasm Invasiveness|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|*Neoplastic Processes|Biomarkers, Tumor|Cell Proliferation|Antigens, Surface|TM4SF1 protein, human 102 TM4SF5 31501417 Cell Death Dis 2019 PMC6733838 10.1038/s41419-019-1878-5 1 2 0 210 Mice|Animals|*Alveolar Epithelial Cells|*Idiopathic Pulmonary Fibrosis|Lung|Bleomycin|Signal Transduction|Membrane Proteins|Cells, Epithelial|*RNA Splicing|Cell Survival 57 TM4SF5 31186734 Oncol Lett 2019 PMC6507443 10.3892/ol.2019.10210 0 0 0 210 Mice|Animals|Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Prognosis|Immunohistochemistry|Cell Line, Tumor|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Membrane Proteins|Cell Proliferation|TM4SF5 protein, human 57 TM4SF5 30956113 Cell Metab. 2019 10.1016/j.cmet.2019.03.005 3 7 0 210 *Arginine|Molecular Docking Simulation|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|SLC38A9 protein, human|Amino Acid Transporter|Multiprotein Complexes|Mechanistic Target of Rapamycin Complex 1|Lysosome|Intracellular Signaling Peptides and Proteins|Carrier Proteins|Models, Molecular|Amino Acids|Biological Transport 57 TMC1 31854501 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2019 10.1002/ajmg.b.32774 1 0 0 66 Humans|Mice|Animals|Nonsyndromic Deafness|Saudi Arabia|*Deafness|Deafness, Autosomal Recessive 7|Hearing Loss, Sensorineural|Deafness, Autosomal Dominant 36|Hearing Loss|Mutation|DNA Mutational Analysis|Pedigree|Connexins|Hair Cells, Cochlear|Phenotype|Genetic Linkage|Membrane Proteins|Ear, Inner|TMC1 protein, human|TMC1 protein, mouse 163 TMC1 31761710 Neuron 2019 10.1016/j.neuron.2019.10.017 5 0 0 66 Humans|Mice|Animals|Mechanotransduction, Cellular|Hair Cells, Auditory|Hair Cells, Auditory, Inner|Stereocilia|Hair Cells, Vestibular|*Ion Channel|Membrane Proteins|Deafness|Mutation|TMC1 protein, human|TMC1 protein, mouse|TMC2 protein, mouse 163 TMC1 31661074 Elife 2019 PMC6853638 10.7554/eLife.47441 1 0 0 66 Mice|Animals|*Hair Cells, Auditory|Hair Cells, Auditory, Inner|Cochlea|Mechanotransduction, Cellular|Membrane Proteins|Hearing|Animals, Newborn|Calcium|TMC1 protein, mouse 163 TMC1 31649296 Sci Rep 2019 PMC6813322 10.1038/s41598-019-51336-0 0 0 0 66 Mice|Animals|Humans|Mechanotransduction, Cellular|HEK293 Cells|*Plasma Membrane|Hair Cells, Auditory|Stereocilia|*Protein Transport|Membrane Proteins|Hair Cells, Auditory, Inner|Endoplasmic Reticulum|*Cell Movement|TMC1 protein, human|TMC1 protein, mouse 163 TMC1 31633194 J. Physiol. (Lond.) 2019 PMC6910908 10.1113/JP278799 1 0 0 66 Animals|*Hair Cells, Auditory, Outer|Hair Cells, Auditory, Inner|Mechanotransduction, Cellular|Membrane Proteins|Deafness|Animals, Newborn|Mutation|Calcium|*Acclimatization 163 TMC1 31585078 Cell 2019 10.1016/j.cell.2019.08.049 3 0 0 66 Animals|*Ion Channel|Ion Channel Gating|Mechanotransduction, Cellular|Potassium Channels, Tandem Pore Domain|*Mammals|*Physical Phenomena|*Mechanical Phenomena 163 TMC1 31584127 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03214-1 1 0 0 66 Ion Channels|Ion Channel Gating|Mechanotransduction, Cellular|Hearing|Membrane Proteins|Deafness|Mutations 163 TMC1 31548403 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6789967 10.1073/pnas.1908058116 2 0 0 66 Mice|Animals|Hair Cells, Auditory, Outer|Mechanotransduction, Cellular|Membrane Proteins|Mutations|Patch-Clamp Techniques|Animals, Newborn|Calcium 163 TMC1 31389194 Mol Genet Genomic Med 2019 PMC6732339 10.1002/mgg3.917 0 0 0 66 Humans|Nonsyndromic Deafness|Pakistan|*Deafness|Nonsyndromic sensorineural hearing loss|Hearing Loss, Sensorineural|Genetic Screening|Hearing Loss|Connexins|High-Throughput Nucleotide Sequencing|Mutation|Genetic Predisposition to Disease|*Cohort Studies|*Ethnic Groups|Membrane Proteins 163 TMC2 31761710 Neuron 2019 10.1016/j.neuron.2019.10.017 5 0 0 41 Humans|Mice|Animals|Mechanotransduction, Cellular|Hair Cells, Auditory|Hair Cells, Auditory, Inner|Stereocilia|Hair Cells, Vestibular|*Ion Channel|Membrane Proteins|Deafness|Mutation|TMC1 protein, human|TMC1 protein, mouse|TMC2 protein, mouse 53 TMC2 31661074 Elife 2019 PMC6853638 10.7554/eLife.47441 1 0 0 41 Mice|Animals|*Hair Cells, Auditory|Hair Cells, Auditory, Inner|Cochlea|Mechanotransduction, Cellular|Membrane Proteins|Hearing|Animals, Newborn|Calcium|TMC1 protein, mouse 53 TMC2 31633194 J. Physiol. (Lond.) 2019 PMC6910908 10.1113/JP278799 1 0 0 41 Animals|*Hair Cells, Auditory, Outer|Hair Cells, Auditory, Inner|Mechanotransduction, Cellular|Membrane Proteins|Deafness|Animals, Newborn|Mutation|Calcium|*Acclimatization 53 TMC2 31548403 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6789967 10.1073/pnas.1908058116 2 0 0 41 Mice|Animals|Hair Cells, Auditory, Outer|Mechanotransduction, Cellular|Membrane Proteins|Mutations|Patch-Clamp Techniques|Animals, Newborn|Calcium 53 TMC2 30737404 Nat Commun 2019 PMC6368561 10.1038/s41467-019-08716-x 0 0 0 41 Mice|Animals|*Hearing|*Hearing Tests|Hair Cells, Vestibular|Hair Cells, Auditory, Inner|Mechanotransduction, Cellular|Membrane Proteins|*Ear Diseases|Genetic Therapy|TMC1 protein, mouse 53 TMC2 30670701 Nat Commun 2019 PMC6342993 10.1038/s41467-018-08264-w 5 0 0 41 Mice|Animals|*Hearing|Hair Cells, Auditory|Hair Cells, Vestibular|*Hearing Tests|Hair Cells, Auditory, Inner|Deafness|Cochlea|Genetic Therapy|Mechanotransduction, Cellular|Labyrinth Diseases|*Ear Diseases|Membrane Proteins 53 TMC8 30982308 Dermatol. Online J. 2019 0 1 0 65 Male|Humans|Adult|Epidermodysplasia Verruciformis|Human Papillomavirus Infection|Papillomaviridae|Mutations|*Skin Abnormalities|Membrane Proteins|*Skin|TMC8 protein, human 50 tmco1 31443641 Genet. Sel. Evol. 2019 PMC6708195 10.1186/s12711-019-0488-0 0 0 0 185 Swine|Animals|*Glycogen|Genome-Wide Association Study|*Meat|Quantitative Trait Loci|Sus scrofa|Quantitative Trait, Heritable|Genetic Linkage|Gene Frequency|Phenotype|Alleles|Crosses, Genetic|Haplotypes|Muscle, Skeletal|Polymorphism, Single Nucleotide|Mutations 42 tmco1 31102500 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61168 0 0 0 185 Humans|*Intellectual Disability|*Abnormalities, Multiple|*Phenotype|*Mutation|Craniofacial Abnormalities|Homozygote|Sequencing, Whole Exome|Facies|*Dysostoses|Musculoskeletal Abnormalities|Exome|Pedigree|Epilepsy|*Thoracic Diseases|Syndrome|Israel 42 tmco1 30962442 Nat Commun 2019 PMC6453895 10.1038/s41467-019-09653-5 3 56 0 185 Core Binding Factor Alpha 1 Subunit|Osteogenesis|Osteoblasts|Cell Differentiation|Signal Transduction|Cell Line 42 tmco1 30929916 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.03.115 0 6 0 185 Humans|*Diacylglycerol O-Acyltransferase|*Mitochondria|*Endoplasmic Reticulum Stress|Endoplasmic Reticulum|Lipid Droplets|Triglycerides|Lipid Metabolism|HEK293 Cells 42 tmco1 30901387 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.18-25922 2 0 0 185 *Glaucoma, Primary Open Angle|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Alleles|Genotype|Case-Control Studies 42 tmco1 30862618 Br J Ophthalmol 2019 PMC6817700 10.1136/bjophthalmol-2018-313086 1 0 0 185 *Polymorphism, Single Nucleotide|Glaucoma, Open-Angle|Intraocular Pressure|Genetic Predisposition to Disease|Gene Frequency|Genome-Wide Association Study|Genotype|Case-Control Studies 42 tmco1 30617110 J. Cell. Sci. 2019 PMC6382017 10.1242/jcs.223883 1 1 0 185 glycylphenylalanine 2-naphthylamide|*Lysosomes|*Dipeptides|Inositol 1,4,5-Trisphosphate Receptors|Calcium Signaling|Endoplasmic Reticulum|Calcium|Hydrogen-Ion Concentration 42 TMEFF1 31487395 J. Bone Miner. Res. 2019 10.1002/jbmr.3871 1 1 0 69 Humans|Mice|Animals|BMP2 protein, human|*Bone Morphogenetic Protein 2|*Mesenchymal Stem Cells|Osteogenesis|*Mice, Inbred C57BL|*Bone Regeneration|Cell Differentiation|Bone Marrow Cells|*Transforming Growth Factor|SMAD3 protein, human|Smad3 Protein 26 TMEFF1 31218705 J. Cutan. Pathol. 2019 10.1111/cup.13528 0 0 0 69 Male|*Carcinoma, Merkel Cell|*Testis|Skin Neoplasms|Prognosis|Biomarkers, Tumor 26 TMEFF1 30697076 Cancer Manag Res 2019 PMC6340504 10.2147/CMAR.S186080 2 4 0 69 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction|Cell Movement|Cell Line, Tumor|MicroRNAs|Apoptosis|*Cell Transformation, Neoplastic 26 TMEM106B 31835286 Neuroimage Clin 2019 PMC6911860 10.1016/j.nicl.2019.102077 0 0 0 173 Humans|*Progranulins|*Frontotemporal Dementia|*White Matter|*Pick Disease of the Brain|*Longitudinal Study|Grey Matter|Heterozygote|Mutation|Atrophy|*Leukoaraiosis|Magnetic Resonance Imaging|Genotype|Biomarkers|TMEM106B protein, human|Membrane Proteins|Nerve Tissue Proteins 100 TMEM106B 31709544 J. Cell. Physiol. 2019 10.1002/jcp.29360 0 4 0 173 *Colorectal Cancer|RNA, Long Noncoding|Cell Proliferation|Cell Migration|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|*Disease Progression|Downregulation|Apoptosis|Cell Line, Tumor|Upregulation|*Neoplastic Processes|*Colonic Neoplasms|Messenger RNA 100 TMEM106B 31687268 Curr Genet Med Rep 2019 PMC6827567 10.1007/s40142-019-0160-6 1 0 0 173 Humans|*Frontotemporal Dementia|*Pick Disease of the Brain|C9orf72 Protein|Progranulins|Amyotrophic Lateral Sclerosis|tau Proteins|Intercellular Signaling Peptides and Proteins|Mutation 100 TMEM106B 31456032 Acta Neuropathol. 2019 PMC6942643 10.1007/s00401-019-02066-0 1 0 0 173 Humans|Frontotemporal Lobar Degeneration|*Neurons|Nerve Tissue Proteins|Progranulins|Membrane Proteins|Frontotemporal Dementia|Alzheimer Disease|Neurofibrillary Tangles|Polymorphism, Single Nucleotide|Mutation|Brain|Cerebral Cortex|TMEM106B protein, human 100 TMEM106B 31376286 Brain Pathol. 2019 PMC7065086 10.1111/bpa.12773 1 1 0 173 *Alleles|*Sclerosis|*Autopsy|Single Nucleotide Polymorphism|Hippocampus|Genetic Predisposition to Disease|Progranulins|Brain|Nerve Tissue Proteins|Sulfonylurea Receptors|Cognitive Dysfunction|Genotype|DNA-Binding Proteins|Membrane Proteins|Encephalopathy|Cohort Studies|Nerve Degeneration 100 TMEM106B 31127772 J. Alzheimers Dis. 2019 10.3233/JAD-181256 0 0 0 173 Humans|Adult|Middle Aged|Aged|*Alzheimer Disease|*Frontotemporal Dementia|*Frontotemporal Lobar Degeneration|Presenilin-2|Presenilin-1|C9orf72 Protein|Onset Age|*DNA Mutational Analysis|Genetic Association Studies|Mutation|Genetic Predisposition to Disease|Phenotype|Sequencing, Next-Generation|Cohort Studies|TREM2 protein, human|Membrane Glycoproteins|Receptors, Immunologic|UBQLN1 protein, human 100 TMEM106B 31119452 J. Neurol. 2019 PMC6647117 10.1007/s00415-019-09363-4 6 0 0 173 Humans|*Frontotemporal Dementia|*Pick Disease of the Brain|C9orf72 Protein|Progranulin|Heterozygote|tau Proteins|Mutations|Grey Matter|Magnetic Resonance Imaging|Cohort Studies|Polymorphism, Genetic|Canada|Europe|TMEM106B protein, human|Membrane Proteins|Nerve Tissue Proteins|C9orf72 protein, human 100 TMEM106B 31039256 Brain 2019 PMC6536849 10.1093/brain/awz099 55 0 0 173 *Consensus|Retrospective Studies|TDP-43 Proteinopathy|Frontotemporal Lobar Degeneration|Frontotemporal Dementia|Alzheimer Disease|tau Proteins|Brain|Tauopathy|*DNA-Binding Proteins|Temporal Lobe|Frontal Cortex|Neuroimaging|*Limbic Encephalitis|Atrophy|Autopsy 100 TMEM106B 30973966 Ann. Neurol. 2019 PMC6953172 10.1002/ana.25486 2 0 0 173 *Frontotemporal Dementia|*Parkinson Disease|*Pick Disease of the Brain|*Cognition|Cognitive Decline|Neuropsychological Tests|Genotype|Nerve Tissue Proteins|Membrane Proteins 100 TMEM106B 30682540 Neurobiol. Dis. 2019 PMC6696921 10.1016/j.nbd.2019.01.013 2 1 0 173 Humans|Aged|*TDP-43 Proteinopathy|*Aging|*Brain|Alzheimer Disease|Hippocampal Formation|Cognitive Impairment|*Thyroid Hormones|Polymorphism, Single Nucleotide|Sclerosis|Cohort Studies|Genotypes|Sulfonylurea Receptors|*Thyroid Gland|Triiodothyronine|DNA-Binding Proteins|SLCO1A2 protein, human|Organic Anion Transporters|TDP-43 protein, human 100 TMEM106B 30655286 J. Biol. Chem. 2019 PMC6422082 10.1074/jbc.RA118.005050 6 8 0 173 *RNA, Long Noncoding|Coronary Artery Disease|Atherosclerosis|Genetic Predisposition to Disease|Cell Proliferation|Genotype 100 TMEM135 31140646 Cell Biochem. Funct. 2019 10.1002/cbf.3415 0 2 0 40 Mice|Animals|*Insulin|*Osteoblasts|*Cell Differentiation|Cell Proliferation|*Insulin, Regular, Human|Bone Formation|3T3 Cells|Signal Transduction|Gene Expression|Glucose 20 TMEM135 30779856 J. Bone Miner. Res. 2019 10.1002/jbmr.3703 0 0 0 40 Humans|*Genome-Wide Association Study|*Calcaneus|Osteoporosis|Bone Density|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian|Quantitative Trait Loci|Cohort Studies|Taiwan 20 TMEM135 30705370 Sci Rep 2019 PMC6355770 10.1038/s41598-019-38550-6 6 0 0 40 Humans|Male|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Gene Fusions|Prostate|Prostate Cancers|Gene Expression Profiling|DNA Copy Number Variations|*Databases, Genetic|Oncogene Proteins, Fusion|Carcinoma, Ovarian Epithelial|Ovarian Cancer 20 TMEM163 31813547 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.11.117 0 0 0 9 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Insulin|*Insulin, Lente|Insulin Secretion|*Asian Continental Ancestry Group|Insulin-Secreting Cells|Glucose|Membrane Proteins|Zinc|Homeostasis|TMEM163 protein, human 22 TMEM163 31697912 Arch. Biochem. Biophys. 2019 PMC6864316 10.1016/j.abb.2019.108166 0 0 0 9 Humans|Animals|*Zinc|Phylogeny|Cation Transport Proteins|*Biological Transport|Sequence Alignment|Amino Acid Sequence|zinc-binding protein|Active Transport|Cell Line|Mutant Proteins|Cytoplasm|TMEM163 protein, human|Membrane Proteins 22 TMEM163 31430546 Neurosci. Lett. 2019 10.1016/j.neulet.2019.134425 0 0 0 9 Humans|*Parkinson Disease|*Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Genotype|Asian Continental Ancestry Group|Case-Control Studies|*Risk Factors|Cohort Studies|Spain 22 TMEM163 31417298 Diabetes Metab Syndr Obes 2019 PMC6602052 10.2147/DMSO.S207019 1 3 0 9 22 TMEM163 30880162 Neurosci. Lett. 2019 10.1016/j.neulet.2019.03.019 0 0 0 9 Humans|*Parkinson Disease|Genome-Wide Association Study|*Chinese|Genetic Association Studies|Genetic Predisposition to Disease|Allele Frequency|Polymorphism, Single Nucleotide|Allele|Genotype|Case-Control Studies|*Transcription Factors|Age-at-Onset|Protein-Serine-Threonine Kinases|*Genes, Regulator|Mainland China|GPNMB protein, human|Membrane Glycoproteins|TMEM163 protein, human 22 TMEM163 30719275 Parkinsons Dis 2019 PMC6334313 10.1155/2019/3489638 0 0 0 9 Humans|Genome-Wide Association Study|Asian|Genetic Predisposition to Disease|Genetic Association Studies|Genetic Loci|Polymorphism, Single Nucleotide|Parkinson Disease|Genotype|Case-Control Studies|European Continental Ancestry Group|aminocarboxymuconate-semialdehyde decarboxylase|Carboxy-Lyases 22 TMEM165 31652305 Biochem. J. 2019 10.1042/BCJ20190488 0 2 0 47 40 TMEM165 31541377 Biometals 2019 10.1007/s10534-019-00216-1 0 3 0 47 Humans|*Manganese|Cation Transport Proteins|Biological Transport|Hepatocyte 40 TMEM165 31415112 J. Inherit. Metab. Dis. 2019 PMC7021577 10.1002/jimd.12161 0 2 0 47 40 TMEM165 31351090 Biochimie 2019 PMC6857530 10.1016/j.biochi.2019.07.016 2 0 0 47 Humans|*Glycosylation|*Golgi Apparatus|Congenital Disorders of Glycosylation|Membrane Proteins|Calcium|Homeostasis|Manganese|HeLa Cells|Mutation|TMEM165 protein, human 40 TMEM165 31319631 Genes (Basel) 2019 PMC6678438 10.3390/genes10070545 0 0 0 47 Humans|*Saccharomyces cerevisiae|*Manganese|*Yeast, Dried|Golgi Apparatus|Homeostasis|Congenital Disorders of Glycosylation|Glycosylation|*Ions|Kufor-Rakeb syndrome|Parkinsonian Disorders|Membrane Proteins|HEK293 Cells|TMEM165 protein, human 40 TMEM165 30674975 Sci Rep 2019 PMC6344567 10.1038/s41598-018-36840-z 8 0 0 47 Humans|Dogs|Animals|*Osteosarcomas|Sequencing, RNA|High-Throughput Nucleotide Sequencing|Computational Biology|Oncogene Proteins, Fusion|Antigens, Neoplasm|Cell Line, Tumor|RNA Splicing|Base Sequence|Immunotherapy 40 TMEM165 30622138 J. Biol. Chem. 2019 PMC6398142 10.1074/jbc.RA118.006270 2 0 0 47 Animals|Female|*Milk|*Golgi Complex|Lactation|Cation Transport Proteins|Mammary Glands, Animal|Antiporters|Congenital Disorders of Glycosylation|*Cations|Calcium|Homeostasis|Manganese|Lactose|Glycosylation 40 TMEM18 31628562 Biochem. Genet. 2019 10.1007/s10528-019-09940-2 0 1 0 59 Humans|Pakistan|*Overweight|*Obesity|*Anthropometry|Body Mass Index|Genotype|Polymorphism, Single Nucleotide|Alleles|Physical Activity|*Phenotype|TMEM18 protein, human|Membrane Proteins 135 TMEM18 31361511 DNA Cell Biol. 2019 10.1089/dna.2019.4827 0 1 0 59 Pregnancy|Humans|Female|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genetic Association Studies|Diabetes, Gestational|Alleles|Genotype|Case-Control Studies 135 TMEM18 31354816 Int J Endocrinol 2019 PMC6634012 10.1155/2019/4764751 1 1 0 59 Adult|Child|Humans|Child, Preschool|Adolescent|*Adipokines|Genome-Wide Association Study|Case-Control Studies|Mexico|*Obesity|Body Mass Index|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Alleles|Genotype|Membrane Proteins 135 TMEM18 31288024 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.07.004 0 5 0 59 Rats|Animals|*Osteogenesis|*Mesenchymal Stem Cells|*Bone Marrow|*Cell Differentiation|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteoblasts|Bone Marrow Cells|Wnt Signaling Pathway|beta Catenin|Osteocalcin|*Catenins|Cells, Cultured|Adipogenesis|Osteopontin|Alkaline Phosphatase 135 TMEM18 31167208 Obes Facts 2019 PMC6696887 10.1159/000500490 1 1 0 59 Middle Aged|Male|Humans|Female|*Diabetes Mellitus, Type 2|*Sex Characteristics|*Chinese|*Obesity|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Risk Factors|Body Mass Index|*Phenotype|Alleles|Genotype|China 135 TMEM18 31046077 Hum. Mol. Genet. 2019 PMC6606847 10.1093/hmg/ddz061 2 0 0 59 *Taste|*Genome-Wide Association Study|*Beverage|Taste Perception|Sweetener|Coffee|Food Preferences|Citrus paradisi|*Dysgeusia|Alcoholic Beverages|*Candy|Fruit and Vegetable Juices 135 TMEM18 30993211 Commun Biol 2019 PMC6453927 10.1038/s42003-019-0339-0 8 0 0 59 Humans|*Uric Acid|Japan|Gout|Hyperuricemia|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Genotype|Case-Control Studies 135 TMEM18 30887699 Obesity (Silver Spring) 2019 PMC6478540 10.1002/oby.22433 2 1 0 59 Humans|*Indians, North American|Genome-Wide Association Study|*Body Mass Index|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Obesity|Diabetes Mellitus, Type 2 135 TMEM18 30753134 J. Mol. Endocrinol. 2019 10.1530/JME-18-0215 0 3 0 59 Humans|Mice|Animals|*RNA, Long Noncoding|Adipogenesis|*Cell Differentiation|Adipocytes|Adipose Tissue|3T3-L1 Cells|Obesity 135 TMEM38B 31218223 Biomed Res Int 2019 PMC6537022 10.1155/2019/2492590 1 0 0 37 Pregnancy|Humans|Female|*Whole Exome Sequencing|*Fetus|*Genetic Testing|*Osteochondrodysplasias|*Prenatal Care|Prenatal Diagnosis|Ultrasonography, Prenatal|Karyotyping|Exome|DNA Copy Number Variations|*Musculoskeletal Abnormalities 25 TMEM38B 30913006 Endocr Pract 2019 10.4158/EP-2018-0443 2 0 0 37 Humans|*Osteogenesis Imperfecta|Phenotypes|*Chinese|Mutations|Genetic Association Studies|Collagen Type I|High-Throughput Nucleotide Sequencing|WNT1 protein, human|Wnt1 Protein|P4HB protein, human|Procollagen-Proline Dioxygenase|Protein Disulfide-Isomerases|TMEM38B protein, human|Ion Channels 25 TMEM70 31729175 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61383 0 0 0 63 Child|Infant, Newborn|Humans|Adult|Adolescent|3-Methylglutaconic Aciduria|Retrospective Studies|*Metabolism, Inborn Errors|Barth Syndrome|*Cardiomyopathies|3-methylglutaconic acid|Glutarates|Mutations|Transcription Factors 44 TMEM70 31652072 FASEB J. 2019 10.1096/fj.201900685RR 1 1 0 63 Animals|Mitochondrial Proton-Translocating ATPases|Mitochondrial Proteins|*Mammals|Membrane Proteins|Mitochondria|*Nitric Oxide Synthase|Mutation|Adenosine Triphosphate 44 TMEM70 30950220 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61138 0 0 0 63 Humans|oligomycin sensitivity-conferring protein|Mitochondrial Proton-Translocating ATPases|Mitochondrial Proteins|Membrane Proteins|Mutations|Hyperammonemia|Mitochondrial Membranes|Cardiomyopathy, Hypertrophic|Chain, Respiratory|Acidosis, Lactic|Cell Nucleus|TMEM70 protein, human 44 TMEM70 30899493 Clin Case Rep 2019 PMC6406168 10.1002/ccr3.2050 0 1 0 63 *Mitochondria|Mitochondrial Proteins|Mitochondrial Proton-Translocating ATPases|Membrane Proteins|Mutation|Fibroblasts 44 TNFAIP2 31549342 Arch. Pharm. Res. 2019 10.1007/s12272-019-01187-0 0 0 0 118 Male|Mice|Animals|amentoflavone|*Biflavonoids|*Mice, Inbred C57BL|*Hematopoietic System|Radiation-Protective Agents|Radiation Injuries, Experimental|Whole-Body Irradiation|Gamma Rays|Antioxidants|Micronucleus Tests|DNA Damage|Oxidative Stress|Plant Extracts|Flavonoids|Liver 64 TNFAIP2 31392347 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03265-4 2 0 0 118 *Open Reading Frames|Protein Biosynthesis|5' Untranslated Regions|Ribosomes|mRNA|Saccharomyces cerevisiae|Protein Processing, Post-Translational|Conserved Sequence 64 TNFAIP2 31300557 J. Biol. Chem. 2019 PMC6721953 10.1074/jbc.RA118.006865 1 1 0 118 *Chondrocytes|*Proteomics|Articular Cartilage|Osteoarthritis|Interleukin-1beta|MMP13 protein, human|Matrix Metalloproteinase 13|Extracellular Matrix|Cells, Cultured|Cytokines 64 TNFAIP2 31263157 Lab. Invest. 2019 10.1038/s41374-019-0285-y 2 4 0 118 Humans|TWIST1 protein, human|Twist-Related Protein 1|*Epithelial-Mesenchymal Transition|*Carcinoma, Transitional Cell|*Urinary Bladder Neoplasms|CDH1 protein, human|E Cadherin|Cisplatin|Nuclear Proteins|Drug Resistance, Neoplasm|Antigens, CD|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|Cell Proliferation|Urologic Neoplasms|Signal Transduction|RNA, Small Interfering 64 TNFAIP2 31244859 Front Immunol 2019 PMC6579949 10.3389/fimmu.2019.01323 3 0 0 118 Mice|Animals|*Immunity, Mucosal|*Disease Models, Animal|TNFSF11 protein, human|*RANK Ligand|*Intestinal Mucosa|Peyer Patches|*Signal Transduction|Cell Differentiation|*B Cells|Tissues, Lymphoid|Stem Cells|Intestine|*Epithelium|Antigens|*Duodenum|*Bronchioles|*Gastric Mucosa 64 TNFAIP2 30877198 J. Biol. Chem. 2019 PMC6509506 10.1074/jbc.RA118.005659 2 0 0 118 Animals|*Molecular Chaperones|Heat-Shock Proteins|Endoplasmic Reticulum|Protein Folding|mRNA|Cell Line|siRNA|*Nanotube 64 TNFAIP2 30659112 J. Cell. Sci. 2019 PMC6382011 10.1242/jcs.223321 13 1 0 118 Animals|*Cell Communication|*Macrophage|Mammary Neoplasms, Animal|Signal Transduction|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Nanotubes|*Neoplastic Processes|Cell Proliferation 64 TNFAIP6 31772617 Cardiovasc Ther 2019 PMC6739802 10.1155/2019/8490707 2 5 0 517 *Computational Biology|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Databases, Genetic|*Signal Transduction|Protein Interaction Mapping|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|*Myocardial Infarction 400 TNFAIP6 31686624 Tissue Eng Part C Methods 2019 10.1089/ten.TEC.2019.0195 0 0 0 517 400 TNFAIP6 31667700 J. Assist. Reprod. Genet. 2019 PMC7000615 10.1007/s10815-019-01610-x 1 3 0 517 Humans|Female|Animals|Mice|*Oocyte|Oocyte In Vitro Maturation|Cumulus Cells|Oogenesis|Meiosis|1-Methyl-3-isobutylxanthine|Natriuretic Peptide, C-Type|Embryonic Development 400 TNFAIP6 31548612 Oncogene 2019 PMC6976524 10.1038/s41388-019-1023-z 2 2 0 517 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Signal Transduction|Epithelial-Mesenchymal Transition|Protein-Serine-Threonine Kinases|Cell Cycle Proteins|Phosphorylation|Transforming Growth Factor beta|Cell Motility|Gene Expression Regulation, Neoplastic|MicroRNAs|*Neoplastic Processes|Cell Line, Tumor|Prognosis 400 TNFAIP6 31547322 Cells 2019 PMC6769700 10.3390/cells8091074 1 2 0 517 Humans|Mice|Animals|*Hyaluronic Acid|*Intestinal Mucosa|Colitis, Ulcerative|Colitis|*Wound Healing|Dextran Sulfate|Disease Models, Animal 400 TNFAIP6 31491901 Cells 2019 PMC6770505 10.3390/cells8091031 1 2 0 517 Animals|Humans|*Mesenchymal Stem Cells|Mesenchymal Stem Cell Transplantation|Culture Media, Conditioned|Spheroids, Cellular|Cell Culture Techniques|Cells, Cultured|Cell Proliferation|Prostaglandin E2|TNFalpha 400 TNFAIP6 31368632 Mol. Reprod. Dev. 2019 10.1002/mrd.23249 0 0 0 517 Female|Swine|Animals|*Coculture Techniques|*Vitrification|*Oocytes|Cumulus Cells|In Vitro Oocyte Maturation Techniques|Cryopreservation|Cryoprotective Agents|Blastocyst|Embryo Development|Fertilization in Vitro|Bone Morphogenetic Protein 15|Glutathione 400 TNFAIP6 31363052 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6697797 10.1073/pnas.1821601116 7 22 0 517 Mice|Animals|*Neutrophils|*Macrophages|STAT6 protein, human|*STAT6 Transcription Factor|*Inflammation|Lipopolysaccharides|*Apoptosis|Signal Transduction|Cytokines|Lungs|*Leukocyte Count|Macrophages, Alveolar|*Homeostasis|Acute Lung Injury|Stat6 protein, mouse 400 TNP1 31793700 Andrologia 2019 10.1111/and.13483 0 0 0 248 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Testis|*Semen|*Spermatogenesis|Sperm Retrieval|Spermatozoa|*Biomarkers|Real Time Polymerase Chain Reaction|mRNA 93 TNP1 31541158 Sci Rep 2019 PMC6754440 10.1038/s41598-019-50052-z 0 1 0 248 Mice|Male|Animals|*Nuclear Protein|*mRNA|*Testis|*RNA-Binding Proteins|spermatid transition proteins|Chromosomal Proteins, Non-Histone|Spermatogenesis|DNA-Binding Proteins|RNA|Germ Cells|Cell Nucleus|*Mass Spectrometry|Tnp2 protein, mouse 93 TNP1 31328782 Mol. Hum. Reprod. 2019 10.1093/molehr/gaz043 0 3 0 248 Humans|Male|Animals|Swine|*Haploidy|Spermatogonia|Spermatogenesis|Spermatids|Seminiferous Tubule|Spermatozoa|Testis|Retinoic Acid|Sertoli Cells|Cell Differentiation|Meiosis|Akrosin|Oocytes|*Hematopoiesis|Adult Germline Stem Cells|Adaptor Proteins, Signal Transducing 93 TNP2 31692026 Andrologia 2019 10.1111/and.13450 0 5 0 42 Male|Animals|Mice|*Zinc Oxide|*Hyssopus Plant|*BALB C Mice|*Prostate|*Spermatogenesis|*Testis|Green Chemistry Technology|Metal Nanoparticles|Plant Leaves|Cell Survival|Plant Extracts|*Plant Oils|Tnp2 protein, mouse|Nuclear Proteins|Adam3 protein, mouse|Membrane Glycoproteins|ADAM Proteins 118 TNP2 31583373 Int J Reprod Biomed (Yazd) 2019 PMC6745086 10.18502/ijrm.v17i8.4821 0 0 0 42 Humans|Male|Varicocele|Infertility, Male|Sperm Count|Sperm|DNA Damage|Chromosomal Proteins, Non-Histone|Polymorphism, Single Nucleotide|Case-Control Studies 118 TNP2 31541158 Sci Rep 2019 PMC6754440 10.1038/s41598-019-50052-z 0 1 0 42 Mice|Male|Animals|*Nuclear Protein|*mRNA|*Testis|*RNA-Binding Proteins|spermatid transition proteins|Chromosomal Proteins, Non-Histone|Spermatogenesis|DNA-Binding Proteins|RNA|Germ Cells|Cell Nucleus|*Mass Spectrometry|Tnp2 protein, mouse 118 TNP2 31489793 Andrology 2019 10.1111/andr.12694 0 0 0 42 Humans|Male|Mice|Animals|bisphenol A|*Spermatozoa|bisphenol B|*Benzhydryl Compounds|*Phenols|Semen Analysis|DNA Fragmentation|Spermatogenesis|Infertility, Male|In Situ Nick-End Labeling|Protamines|Testis|*DNA|Chromatin 118 TNPO3 31765392 PLoS Genet. 2019 PMC6901260 10.1371/journal.pgen.1008459 1 1 0 229 Humans|*Splicing Factors|*mRNA|Clk dual-specificity kinases|Protein-Tyrosine Kinases|Protein-Serine-Threonine Kinases|RNA Splicing|RNA Precursors|Phosphorylation|Alternative Splicing|Serine-Arginine Splicing Factors|*Cell Nucleus|Nuclear Proteins|HeLa Cells|lncRNA|TNPO3 protein, human|beta Karyopherins 81 TNPO3 31674007 Clin. Genet. 2019 PMC7307605 10.1111/cge.13665 0 0 0 229 Humans|*Autism Spectrum Disorder|Macrocephaly|Genotype-Phenotype Correlations|Mutations|DNA-Binding Proteins|Microcephaly|Phenotype|PTEN protein, human|PTEN Phosphohydrolase|Transcription Factors|Genetic Predisposition to Disease|Sequencing, Whole Exome|*Cohort Studies|TNPO3 protein, human|beta Karyopherins 81 TNPO3 31465518 PLoS Pathog. 2019 PMC6715175 10.1371/journal.ppat.1007958 0 1 0 229 Humans|*HIV-1|*Limb Girdle Muscular Dystrophy|*HIV Infections|beta Karyopherins|*Mutation|integration, Viral|Transport, Nuclear|Virus Replication|Capsid|Capsid Proteins|TNPO3 protein, human 81 TNPO3 31421124 J. Invest. Dermatol. 2019 10.1016/j.jid.2019.06.147 2 2 0 229 *Alleles|Genome-Wide Association Study|*Single Nucleotide Polymorphism|IRF5 protein, human|*Interferon Regulatory Factors|Genetic Predisposition to Disease|Haplotypes|Lupus Erythematosus, Systemic|Sclerosis, Systemic|Case-Control Studies|Chromatin|Gene Expression Regulation|Autoimmune Diseases 81 TNPO3 31341054 J. Virol. 2019 PMC6798100 10.1128/JVI.00364-19 2 2 0 229 Humans|*HIV-1|*RNA, Micro|*mRNA|Virus Replication|beta Karyopherins|Host-Pathogen Interactions|Nuclear Import|Downregulation|*HIV Seropositivity|Interferons|TNPO1 protein, human|TNPO3 protein, human|MIRN128 microRNA, human 81 TNPO3 31217819 Ther Adv Neurol Disord 2019 PMC6558532 10.1177/1756286419850433 0 0 0 229 Humans|Child|Limb Girdle Muscular Dystrophy|Pedigree|Muscular Atrophy|Muscle, Skeletal|Mutation|Phenotype|*Biological Variation, Population|Imaging, Magnetic Resonance|TNPO3 protein, human|beta Karyopherins 81 TNPO3 31192305 Neurol Genet 2019 PMC6515942 10.1212/NXG.0000000000000337 0 0 0 229 Muscular Dystrophies, Limb-Girdle|Myopathy|Pedigree|beta Karyopherins|Muscle, Skeletal|Mutation 81 TNPO3 31188284 Menopause 2019 PMC7008937 10.1097/GME.0000000000001367 0 0 0 229 Humans|Female|*Longevity|Genetic Association Studies|Polymorphism, Single Nucleotide|Genotype|Menopause|Reproduction 81 TNPO3 31071488 Eur J Med Genet 2019 10.1016/j.ejmg.2019.05.001 1 1 0 229 Humans|Female|Hungary|*Muscular Dystrophies, Limb Girdle|Whole Exome Sequencing|Pedigree|beta Karyopherins|Muscle, Skeletal|Mutation|TNPO3 protein, human 81 TNPO3 31066050 Ann. Hum. Genet. 2019 10.1111/ahg.12319 0 0 0 229 *Muscular Dystrophies, Limb Girdle|*Sequencing, Next-Generation|Sequence Analysis, DNA|Mutation 81 TNPO3 30916345 Nucleic Acids Res. 2019 PMC6511849 10.1093/nar/gkz206 3 2 0 229 Humans|Animals|*Polyadenylation|*Active Transport, Cell Nucleus|*Phosphorylation|mRNA Cleavage and Polyadenylation Factors|beta Karyopherins|mRNA|HIV-1|Cytoplasm|3' Untranslated Regions|Gene Expression Regulation|TNPO1 protein, human|TNPO3 protein, human 81 TNS1 31866765 Cancer Cell Int. 2019 PMC6916460 10.1186/s12935-019-1056-y 0 0 0 410 *Urinary Bladder Neoplasms|*Prognosis|*Transcriptome|Neoplasm Invasiveness|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease Progression|Muscle 79 TNS1 31831813 Sci Rep 2019 PMC6908681 10.1038/s41598-019-55405-2 0 4 0 410 Humans|Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|Asthma|Lung|Airway Remodeling|Bronchi|Muscle, Smooth|Smooth Muscle Cells|Smoking|Airway Obstruction|Contractile Proteins|Cells, Cultured|Collagen 79 TNS1 31805718 Medicina (Kaunas) 2019 PMC6955913 10.3390/medicina55120768 0 0 0 410 79 TNS1 31784086 Biochem. Biophys. Res. Commun. 2019 PMC6981048 10.1016/j.bbrc.2019.11.153 0 0 0 410 Humans|Animals|*Caenorhabditis elegans|*Tensins|Microfilament Proteins|Focal Adhesion|Signal Transduction|Amino Acid Sequence|Cell Adhesion Molecules 79 TNS1 31747387 Med. Sci. Monit. 2019 PMC6880644 10.12659/MSM.916902 3 0 0 410 Humans|*miRNAs|*Messenger RNA|*Computational Biology|*Stomach Neoplasms|*circRNA|Gene Ontology|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Microarray Analysis|Prognosis|Signal Transduction|Genes, cdc 79 TNS1 31740667 Cell Death Dis 2019 PMC6861224 10.1038/s41419-019-2119-7 0 2 0 410 Mice|Animals|Polycystic Kidney Diseases|Polycystic Kidney, Autosomal Dominant|Kidneys|Signal Transduction|Cysts|MEK-ERK Pathway|Cell Proliferation|Mice, Knockout|Upregulation 79 TNS1 31527270 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6778260 10.1073/pnas.1911865116 1 1 0 410 *Keratin|Mechanotransduction, Cellular|*Cytoskeletal Proteins|*Cytoskeleton|Tensins|*Cells, Epithelial|Microfilament Proteins|Intermediate Filaments|Cell Movement|Actin|Actin Cytoskeleton|Cell Line, Tumor|*Cell Count 79 TNS1 31264439 Acta Med Acad 2019 10.5644/ama2006-124.248 0 0 0 410 Humans|Female|*Leiomyosarcoma|*Uterine Neoplasms|*Neoplasms, Connective and Soft Tissue|Anaplastic Lymphoma Kinase|*Uterus|Receptor Protein-Tyrosine Kinases|Biomarkers, Tumor 79 TNS1 31121144 Am. J. Obstet. Gynecol. 2019 10.1016/j.ajog.2019.05.018 2 0 0 410 Humans|Female|*Leiomyosarcoma|*Diagnosis, Differential|*Leiomyoma|Uterine Neoplasms|*Whole Exome Sequencing|*Base Sequence|*Sequencing, RNA|*DNA|Biomarkers, Tumor|Morcellation 79 TNS1 30869175 J. Anim. Breed. Genet. 2019 10.1111/jbg.12389 0 0 0 410 Genome-Wide Association Study|*Phenotype|Quantitative Trait Loci|Quantitative Trait, Heritable|Chromosome Mapping|Crosses, Genetic|Breeding|Genotype|*Sequencing, Whole Genome|Polymorphism, Single Nucleotide 79 TONSL 31576624 J. Anim. Breed. Genet. 2019 PMC7217222 10.1111/jbg.12442 1 0 0 109 Cattle|Female|Animals|*Milk|*Genome-Wide Association Study|*Lactation|*Genome|Dairying|Phenotype|Genotypes|Polymorphism, Single Nucleotide 28 TONSL 31158361 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.05.034 1 4 0 109 *RNA, Long Noncoding|*Stomach Neoplasms|*Disease Progression|Cell Migration|Tumorigenesis|Gene Expression Regulation, Neoplastic|Cell Proliferation|MicroRNAs|Downregulation|Cell Line, Tumor|Upregulation|Signal Transduction|Stomach 28 TONSL 30773278 Am. J. Hum. Genet. 2019 PMC6407524 10.1016/j.ajhg.2019.01.009 0 0 0 109 Female|Mice|Pregnancy|Animals|Spondyloepimetaphyseal dysplasia, sponastrime type|*Osteochondrodysplasias|*Mutations|Sequencing, Whole Exome|Musculoskeletal Abnormalities|Dwarfism|Alleles|Exome|Pedigree|Phenotype 28 TONSL 30773277 Am. J. Hum. Genet. 2019 PMC6408318 10.1016/j.ajhg.2019.01.007 0 1 0 109 Humans|Spondyloepimetaphyseal dysplasia, sponastrime type|Pyle disease|*Osteochondrodysplasias|Strudwick syndrome|*Phenotypes|*Alleles|*Musculoskeletal Abnormalities|Dwarfism|Pedigree|Mutation|TONSL protein, human|NF-kappa B 28 TONSL 30723051 Pathol. Res. Pract. 2019 10.1016/j.prp.2019.01.044 0 1 0 109 *Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|MicroRNAs|Kaplan-Meier Estimate|Disease-Free Survival|Up-Regulation 28 TOR2A 31584433 Anatol J Cardiol 2019 PMC6955075 10.14744/AnatolJCardiol.2019.43247 4 0 0 254 Coronary Circulation|Coronary Angiography|Coronary Artery Disease|Biomarkers|Blood Flow Velocity|Case-Control Studies 64 TOR2A 31486354 Cardiol Young 2019 10.1017/S1047951119001173 1 0 0 254 Child|Humans|*Blood Pressure|Prospective Studies|Body Mass Index|Hypertension|Atherosclerosis|Pediatric Obesity|Cardiovascular System|Biomarkers|Heart Rate|Intercellular Signaling Peptides and Proteins|Adipose Tissue|Case-Control Studies 64 TOR2A 31182692 Iran J Immunol 2019 10.22034/IJI.2019.80261 0 0 0 254 Humans|*Dermcidins|Intercellular Signaling Peptides and Proteins|Case-Control Studies|*Brucellosis 64 TOR2A 30956059 Parkinsonism Relat. Disord. 2019 PMC6739171 10.1016/j.parkreldis.2019.04.003 2 0 0 254 Humans|*Blepharospasm|Dystonia, Focal|Meige Syndrome|*Genetic Screening|Ciz1 protein, human|Nuclear Proteins 64 TOR2A 30738876 Mult Scler Relat Disord 2019 10.1016/j.msard.2019.02.003 1 0 0 254 Humans|*Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|*Plasma|Biomarkers|Peptides|Case-Control Studies 64 TPPP 31723242 Mol. Psychiatry 2019 10.1038/s41380-019-0584-0 0 0 0 1035 Humans|Female|Child|Animals|Mice|Lithium-4|*Lithium|*Rodent|Neurogenesis|*Cognition|Hippocampus|Cranial Irradiation|Cell Proliferation 123 TPPP 31631174 Br. J. Cancer 2019 PMC6888832 10.1038/s41416-019-0604-5 3 3 0 1035 Mice|Animals|*MAPK, p38|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Tubulin|*Pancreatic Cancer|*Neovascularization, Pathologic|Carcinoma, Pancreatic Ductal|Signal Transduction|Cell Movement|Cell Proliferation|Mice, Nude|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Human Umbilical Vein Endothelial Cells|Yy1 protein, mouse|YY1 Transcription Factor 123 TPPP 31522887 Cell 2019 PMC7214773 10.1016/j.cell.2019.08.025 6 0 0 1035 Animals|Mice|*Microtubules|Microtubule-Organizing Center|Tubulin|Oligodendrocytes|Myelin Sheath|Nerve Tissue Proteins|Golgi Apparatus|Axons|Neurons|*Organogenesis 123 TPPP 31505170 Biochim Biophys Acta Mol Cell Res 2019 10.1016/j.bbamcr.2019.118556 0 2 0 1035 Humans|*ELAV-Like Protein 2|HeLa Cells|Tubulin|HDAC6 protein, human|*Histone Deacetylase 6|Microtubule|Nerve Tissue Proteins|Recombinant Proteins|Acetylation|Protein Binding|Immunofluorescence Microscopy|*Transcription Factors|Cell Movement 123 TPPP 31492931 Mod. Pathol. 2019 PMC6930326 10.1038/s41379-019-0351-4 0 0 0 1035 Humans|Female|In Situ Hybridization, Fluorescence|*Adenocarcinoma|Salivary Gland Neoplasms|*Gland, Salivary|*Mutation|Phenotype|Genotype|Protein Kinase C|*Uterine Cervical Neoplasms|Lymphatic Metastasis 123 TPPP 31485733 Acta Neuropathol. 2019 10.1007/s00401-019-02068-y 0 0 0 1035 Male|*Multiple System Atrophy|*alpha-Synuclein|*Oligodendroglia|*alpha Synuclein Pathology|Brain 123 TPPP 31296942 Sci Rep 2019 PMC6624318 10.1038/s41598-019-46424-0 2 0 0 1035 Male|Humans|*Freezing|*Cryopreservation|Semen Preservation|Sperm Motility|Cryoprotective Agents|Spermatozoa|Semen|Membrane Potential, Mitochondrial|*Vibrations, Ultrasonic 123 TPPP 31156389 Front Cell Neurosci 2019 PMC6529516 10.3389/fncel.2019.00192 2 0 0 1035 123 TPPP 31148150 FEBS Lett. 2019 10.1002/1873-3468.13464 0 2 0 1035 *Parkinson Disease|alpha-Synuclein|Multiple System Atrophy|Oligodendrocytes|Brain|Neurons|Protein Conformation 123 TPPP 31031012 Am. J. Hum. Genet. 2019 PMC6507050 10.1016/j.ajhg.2019.03.022 3 0 0 1035 Humans|*Transcription Factors|*Epilepsy|*Mutations|*Neurons|Chromosomal Proteins, Non-Histone|DNA-Binding Proteins|Intellectual Disability|Chromatin Assembly and Disassembly|Heterozygote|Neurodevelopmental Disorders|Hypotonia|Chromatin|Alleles|Pedigree|Phenotype|Brain Disease|Dendrites|FSCN1 protein, human 123 TPPP 31011860 Acta Neuropathol. 2019 PMC7289399 10.1007/s00401-019-02014-y 5 1 0 1035 Humans|Animals|Mice|Rats|*Multiple System Atrophy|SNCA protein, human|*alpha-Synuclein|*Oligodendroglia|*alpha Synuclein Pathology|Myelin|Inclusion Bodies|Neurons|Mice, Transgenic|Brain|Phosphorylation 123 TPPP 30999089 J Affect Disord 2019 10.1016/j.jad.2019.04.049 1 0 0 1035 Child|Humans|*DNA Methylation|*Depression|Child Maltreatment|Adult Survivors of Child Abuse|Depressive Disorder|Anxiety Disorders|Risk Factor|Genetic Variation 123 TPPP 30985858 Genet. Mol. Biol. 2019 PMC6687350 10.1590/1678-4685-GMB-2018-0173 0 0 0 1035 Humans|*Cri-du-Chat Syndrome|Chromosome Deletion|Phenotypes|*Chromosome Structures|SLC6A3 protein, human|Dopamine Plasma Membrane Transport Proteins|CEP72 protein, human|Microtubule-Associated Proteins 123 tppp3 31768046 Nat. Cell Biol. 2019 PMC6895435 10.1038/s41556-019-0417-z 2 0 0 109 Tendon|Tendon Injuries|Tenocytes|Stem Cells|Cell Differentiation|Regeneration|Cells, Cultured|Cell Proliferation 22 tppp3 31488818 Nat Commun 2019 PMC6728361 10.1038/s41467-019-11745-1 1 3 0 109 Mice|Animals|*Sarcoma, Clear Cell|RNA-Binding Protein EWS|Transcription Factors|DNA-Binding Proteins|Oncogene Proteins, Fusion|Activating Transcription Factor 1|Soft Tissue Neoplasms|*B-Lymphocytes|Cell Differentiation|Melanocytes 22 tppp3 30667362 J. Endocrinol. 2019 10.1530/JOE-18-0459 1 10 0 109 Pregnancy|Humans|Female|Mice|Animals|*Cyclooxygenase 2|*BALB C Mice|*Stromal Cell|Implantation, Embryo|Endometrium|Decidua|*Signal Transduction|Uteri|Progesterone|*Epithelial Cells|IGFBP1 protein, human|Insulin-Like Growth Factor Binding Protein 1|*Catenins|beta Catenin|Cell Differentiation|Cells, Cultured|siRNA 22 TRAK2 31490055 J Psychiatry Neurosci 2019 PMC6919916 10.1503/jpn.180098 0 0 0 105 Humans|*Genome-Wide Association Study|African Americans|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Cocaine 46 TRAK2 31118947 Front Genet 2019 PMC6504765 10.3389/fgene.2019.00406 0 0 0 105 Humans|*Esophageal Cancer|Esophageal Squamous Cell Carcinoma|Genome-Wide Association Study|South Africa|Carcinoma, Squamous Cell|Genetic Predisposition to Disease|Chinese|Polymorphism, Single Nucleotide|Case-Control Studies|Interactions, Gene-Environment|Genotype|Alleles|African Continental Ancestry Group|Risk Factors|*Environmental Exposure|Asia 46 TRAK2 31061095 Mol. Cell. Biol. 2019 PMC6597883 10.1128/MCB.00109-19 3 3 0 105 *Mitochondria|Mitochondrial Dynamics|*Cell Motility|GTPases|Mitochondrial Proteins|*Neoplastic Processes|Cell Line, Tumor|Proto-Oncogene Proteins c-myc|Nerve Tissue Proteins|*Protein Transport|Cytoskeleton 46 TRIOBP 31815665 Elife 2019 PMC6927744 10.7554/eLife.50850 0 16 0 239 Mice|Humans|Animals|*Phosphorylation|*Glycogen Synthase Kinase 3|*Neurons|Protein-Tyrosine Kinases|Protein-Serine-Threonine Kinases|Carrier Proteins|*Morphogenesis|Actin Cytoskeleton|Actins|NDEL1 protein, human|Ndel1 protein, mouse 61 TRIOBP 31695490 Cancer Manag Res 2019 PMC6805247 10.2147/CMAR.S228174 0 0 0 239 Humans|*Glioblastoma|*Prognosis|Neoplasm Recurrence, Local|Brain Neoplasms|Biomarkers, Tumor|Immunotherapy|Tumor Microenvironment 61 TRIOBP 31539914 Eur. Heart J. 2019 PMC6698662 10.1093/eurheartj/ehz303 2 2 0 239 *Coronary Artery Disease|Genome-Wide Association Study|*Atherosclerosis|Human Umbilical Vein Endothelial Cells|Signal Transduction|Myocardial Infarction 61 TRIOBP 31486067 Clin. Genet. 2019 10.1111/cge.13638 2 0 0 239 Humans|*Whole Exome Sequencing|*Asian Continental Ancestry Group|Mutations|Deafness|Alleles|Connexins|Sequencing, Next-Generation|Pedigree|Frequencies, Allele|Genetic Variation|Genetic Testing|Hearing Loss|OTOF protein, human|Membrane Proteins 61 TRIOBP 31217345 JCI Insight 2019 PMC6629139 10.1172/jci.insight.128561 4 0 0 239 Humans|Mice|Animals|*Stereocilia|*Hearing|*Hearing Tests|Hair Cells, Auditory, Inner|Hair Cells, Auditory|F-Actin|Actin Cytoskeleton|Microfilament Proteins|Isoforms|Mutations|TRIOBP protein, human 61 TRIOBP 30872186 J Mol Diagn 2019 10.1016/j.jmoldx.2019.02.002 0 0 0 239 Child|Humans|*Disease, Mitochondrial|*Sequencing, Next-Generation|*Mitochondria|DNA, Mitochondrial|*Cell Nucleus|Sequence Analysis, DNA|Exome|Electron Transport|*Cohort Studies|Mutation|Genotype-Phenotype Correlations|Phenotypes|Molecular Diagnostic Techniques|ALAS2 protein, human|5-Aminolevulinate Synthetase 61 TSHZ1 31598948 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.10.015 0 0 0 48 Child|Humans|Chromosome 18 ring|*Ring Chromosomes|*Cytogenetic|*Chromosomes, Human, Pair 18|Karyotyping|Developmental Disabilities|In Situ Hybridization, Fluorescence|Phenotype|Syndactyly 42 TSHZ1 31427287 Development 2019 PMC6765129 10.1242/dev.174045 1 0 0 48 Mice|Animals|*Motor Neurons|Hypoglossal Nerve|Phrenic Nerve|*Neurons, Efferent|Breathing|Diaphragm|Tongue 42 TSHZ1 31170441 Genomics 2019 10.1016/j.ygeno.2019.06.001 0 0 0 48 Animals|Cattle|*Gene Expression Profiling|*Microarray Analysis|Meat|Transcriptome|Adipose Tissue|Phenotype|Paraspinal Muscles 42 TSHZ1 31120642 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61201 1 2 0 48 Humans|Male|Child|Combined Pituitary Hormone Deficiency|*Hypopituitarism|BMP4 protein, human|*Bone Morphogenetic Protein 4|*Mutation|Pituitary Gland|Homeodomain Proteins|Transcription Factors|Dwarfism, Pituitary|Heterozygote|Phenotype|Signal Transduction|Gene Expression Regulation|ALMS1 protein, human|Proteins 42 TSHZ1 30796806 Cereb. Cortex 2019 PMC6917526 10.1093/cercor/bhz018 3 4 0 48 Animals|Mice|*Olfactory Bulb|*Transcription Factors|*Interneurons|proto-oncogene protein Pbx3|Homeodomain Proteins|Neural Stem Cells|Neurogenesis|Cell Differentiation|Gene Expression Regulation, Developmental|Subventricular Zone|Cell Movement 42 TSHZ1 30703237 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.02.016 0 0 0 48 Humans|Male|*Autistic Disorder|*DNA Copy Number Variations|*Microarray Analysis|Genotype|Phenotype|Polymorphism, Single Nucleotide|Pedigree|Chromosome Deletion 42 TSPAN8 31838484 Med. Sci. Monit. 2019 PMC6929559 10.12659/MSM.919749 0 0 0 148 *Colorectal Cancer|beta Catenin|Neoplastic Stem Cells|Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|*Catenins|Cell Line, Tumor|Upregulation|Cell Proliferation|*Colonic Neoplasms|Disease Progression|Promoter Regions, Genetic|Tetraspanins 160 TSPAN8 31790687 Life Sci. 2019 10.1016/j.lfs.2019.117114 0 8 0 148 Histone Demethylases|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Colorectal Cancer|Epithelial-Mesenchymal Transition|Histones|Cell Movement|Cell Line, Tumor|Cell Proliferation|Colonic Neoplasms|*Cell Transformation, Neoplastic 160 TSPAN8 31700906 Ann Transl Med 2019 PMC6803210 10.21037/atm.2019.08.02 0 3 0 148 *Nasopharyngeal Carcinoma|*Proto-Oncogene Proteins c-akt|*Prognosis|Nasopharyngeal Neoplasms|Carcinoma|Cell Movement|Cell Proliferation|Signal Transduction|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Down-Regulation|RNA, Small Interfering|Disease Progression|China 160 TSPAN8 31657037 EMBO J. 2019 PMC6939203 10.15252/embj.2019101828 2 0 0 148 *Epithelial Cells|Tissue Specificity|Transcriptomes|Gene Expression Regulation|Gene Expression Profiling|Transcription Factors|Cell Differentiation|Antigens 160 TSPAN8 31559537 Endocrine 2019 10.1007/s12020-019-02062-0 0 0 0 148 Humans|*MicroRNAs|*Diabetes Mellitus, Type II|Gene Expression Profiling|Insulin Resistance|Insulin-Secreting Cells|mRNA|*Disease Susceptibility|Cell Proliferation 160 TSPAN8 31485223 J Oncol 2019 PMC6702834 10.1155/2019/3516973 0 2 0 148 Humans|*Exosomes|CD44 protein, human|Hyaluronan Receptors|Pancreatic Cancer|TSPAN32 protein, human|Tetraspanins|*Signal Transduction|miRNA|Neoplastic Stem Cells|*Pancreas|Biomarkers, Tumor|Cell Movement|Cell Line, Tumor|mRNA|TSPAN8 protein, human 160 TSPAN8 31361310 Hum. Mol. Genet. 2019 PMC6969355 10.1093/hmg/ddz175 7 0 0 148 Humans|*Rhinitis, Allergic, Seasonal|*Genome-Wide Association Study|United Kingdom|*Biological Specimen Banks|*Eczema|*Asthma|Single Nucleotide Polymorphisms|*European Continental Ancestry Group|Genetic Predisposition to Disease|Genetic Loci|Phenotype|Genotype|Linkage Disequilibrium|TSPAN8 protein, human|Tetraspanins 160 TSPAN8 31276932 Neoplasia 2019 PMC6612010 10.1016/j.neo.2019.06.002 3 4 0 148 Humans|Male|MDV 3100|abiraterone|*Prostatic Neoplasms, Castration-Resistant|*Neoplastic Cells, Circulating|*Phenylthiohydantoin|*Androstenes|AR protein, human|Androgen Receptor|Prostate-Specific Antigen|Kallikreins|Disease-Free Survival|Drug Resistance, Neoplasm|Biomarkers, Tumor|Progression-Free Survival|Kaplan-Meier Estimate|Treatment Outcome|Predictive Value of Tests|SPINK1 protein, human 160 TSPAN8 31253779 Nat Commun 2019 PMC6599078 10.1038/s41467-019-10739-3 7 2 0 148 Humans|Mice|Animals|*Hedgehog Proteins|*Signal Transduction|Cancer Stem Cells|Zinc Finger Protein GLI1|Epithelial-Mesenchymal Transition|Nanog Homeobox Protein|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Transcription Factors|Pancreatic Neoplasms|Antineoplastic Agents|TSPAN8 protein, human|Tetraspanins 160 TSPAN8 31134708 Mol. Reprod. Dev. 2019 10.1002/mrd.23174 0 0 0 148 Cattle|Animals|Male|Humans|Percoll|*Proteomics|Serpin E2|*Spermatozoa|*Fertility|*Povidone|*Silicon Dioxide|Sperm Motility|Cryopreservation|Semen Preservation|Artificial Insemination|Centrifugation, Density Gradient|Semen|*Biomarkers|TSPAN8 protein, human|Tetraspanins|DPY19L2 protein, human|Membrane Proteins 160 TSPAN8 31048929 PLoS ONE 2019 PMC6497273 10.1371/journal.pone.0215990 1 0 0 148 Humans|*Carcinoma, Pancreatic Ductal|*Exosomes|Pancreatic Carcinoma|Pancreatic Cancer|Prognosis|Pancreatectomy|Kaplan-Meier Estimate|Adenocarcinoma|Biomarkers, Tumor|Disease-Free Survival 160 TSPAN8 31030373 Cancer Metastasis Rev. 2019 10.1007/s10555-019-09793-6 6 0 0 148 *Exosomes|*Cancer Stem Cell|Pancreatic Neoplasms|EPCAM protein, human|EpCAM|Signal Transduction|Cell Line, Tumor|Biomarkers, Tumor 160 TSPY1 31805291 Hum. Pathol. 2019 10.1016/j.humpath.2019.11.005 0 0 0 100 Male|Humans|Female|*Gonadoblastoma|Dysgenesis, Gonadal|Germ Cell Neoplasms|Testicular Neoplasms|Ovarian Neoplasms|POU5F1 protein, human|Octamer Transcription Factor-3|Germinoma|Disorders of Sex Development|Biomarkers, Tumor|Sex Development|Germ Cells|Gonad 125 TSPY1 31658757 Int J Mol Sci 2019 PMC6834166 10.3390/ijms20205017 2 0 0 100 Humans|Male|Female|Genome-Wide Association Study|*Germ Cell Cancer|Gonadoblastoma|*Gonad|*Sex Development|Dysgerminoma|Testicular Neoplasms|POU5F1 protein, human|Octamer Transcription Factor-3|Gonadal Dysgenesis|Germ Cells|Proto-Oncogene Proteins c-kit|Disorders of Sex Development|Ovarian Neoplasms|Testis|Ovary|Cell Cycle Proteins|Biomarkers, Tumor 125 TSPY1 31344101 PLoS ONE 2019 PMC6657882 10.1371/journal.pone.0220326 0 0 0 100 Male|Female|*Testis|*Semen|*Nested Polymerase Chain Reaction|Unprotected Sex|Cell Cycle Proteins|Body Fluids|Vagina 125 TSPY1 30815935 Cancer Sci. 2019 PMC6501036 10.1111/cas.13984 4 15 0 100 Humans|Male|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Insulin|*Testis|*Signal Transduction|Hepatocellular Carcinoma|Liver Neoplasms|MTOR protein, human|TOR Serine-Threonine Kinases|Cell Proliferation|Apoptosis|Gene Expression Regulation, Neoplastic|Lung Adenocarcinoma|Cell Line, Tumor|Cell Movement|Mitogen-Activated Protein Kinases|*Insulin, Regular, Human|Lung Neoplasms 125 TTC12 31867628 Nicotine Tob. Res. 2019 10.1093/ntr/ntz240 1 0 0 11 Humans|*Tobacco Use Disorder|*Smokers|*Asian Continental Ancestry Group|Haplotypes|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|*Neural Cell Adhesion Molecules|Genotype|European Continental Ancestry Group|Smoking|Receptors, Dopamine D2|Genetic Variation|Protein-Serine-Threonine Kinases|Epigenesis, Genetic|TTC12 protein, human|Proteins|ANKK1 protein, human 24 TTC12 31428131 Front Genet 2019 PMC6690020 10.3389/fgene.2019.00694 0 0 0 11 Animals|*DNA Methylation|hydrogen sulfite|*Macaca fascicularis|Epigenesis, Genetic|*RNA-Seq|*Sulfites|CpG Islands|*Sequencing, Whole Genome|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|*Whole Exome Sequencing|Promoter Regions, Genetic|Software|Gene Expression Regulation|*Gene Expression|*Biochemical Phenomena|*Brain 24 TTC7A 31787977 Front Immunol 2019 PMC6853864 10.3389/fimmu.2019.02592 0 0 0 51 Humans|*Tetratricopeptide Repeat|Intestinal Atresia, Multiple|Intestinal Atresia|*Phenotype|Inflammatory Bowel Diseases|Mutation|Immunologic Deficiency Syndromes|Proteins|*Intestinal Pseudo-Obstruction|Apoptosis|TTC7A protein, human 34 TTC7A 31743734 Gastroenterology 2019 PMC7062591 10.1053/j.gastro.2019.11.019 1 4 0 51 Humans|Animals|*Leflunomide|*Inflammatory Bowel Disease|Intestinal Atresia, Multiple|Intestinal Atresia|Intestines|Intestinal Mucosa|Enterocolitis|Mutations|Apoptosis|Epithelial Cells|Proteins|Intestinal Obstruction|Disease Models, Animal|TTC7A protein, human 34 TTC7A 31616743 ACG Case Rep J 2019 PMC6658069 10.14309/crj.0000000000000061 0 0 0 51 Humans|Young Adult|Adult|*Inflammatory Bowel Disease|Intestinal Atresia|Pedigree|Proteins|Mutation|Apoptosis|TTC7A protein, human 34 TTC7A 31004027 Haematologica 2019 PMC6939534 10.3324/haematol.2018.207100 1 0 0 51 Mice|Animals|*Hematopoietic Stem Cell|Cell Differentiation|Cell Proliferation|Proteins 34 TTI2 31737043 Front Genet 2019 PMC6830114 10.3389/fgene.2019.01060 0 0 0 57 Humans|*Intellectual Disability|*Heterozygote|*Mutations|Exome|Microcephaly|*Chinese|*Syndromes|Pedigree|Phenotype 25 TTI2 31332096 Mol. Cell. Biol. 2019 PMC6766693 10.1128/MCB.00175-19 0 2 0 57 Yeast, Fission|Schizosaccharomyces pombe Proteins|DNA Replication|Telomere-Binding Proteins|Checkpoint Kinase 2|Cell Cycle Proteins|Protein Kinases|Signal Transduction 25 TTI2 31290144 Clin. Genet. 2019 10.1111/cge.13603 1 0 0 57 Humans|*Intellectual Disability|Molecular Chaperones|Microcephaly|HSP90 Heat-Shock Proteins|Phenotype|Pedigree|Mutation 25 txnl1 30677045 PLoS ONE 2019 PMC6345427 10.1371/journal.pone.0210670 0 0 0 480 Mice|Animals|*Thioredoxin Reductase 1|*Up-Regulation|*Kindling, Neurologic|TXN protein, human|*Thioredoxin|*Seizure|*Cerebral Cortex|*Disease Models, Animal|Oxidation-Reduction|Epilepsy|Oxidative Stress|Hippocampus 37 UBAP2L 31882469 In Vivo 2019 PMC6984086 10.21873/invivo.11751 0 0 0 157 Humans|Female|*Uterine Cervical Neoplasms|Cell Line, Tumor|Cell Proliferation|RNA, Small Interfering|Gene Expression Regulation, Neoplastic|Gene Knockdown Techniques|Carrier Proteins|Signal Transduction|Ubiquitins|Ubap2L protein, human 21 UBAP2L 31636118 J. Cell Biol. 2019 PMC6891081 10.1083/jcb.201904098 2 0 0 157 Humans|Cytoplasmic Granules|Amyotrophic Lateral Sclerosis|Cytoplasm|RNA|Intranuclear Inclusion Bodies|Cell Nucleus|Proteins|Cell Line, Tumor|Stress, Physiological|Ubap2L protein, human|Carrier Proteins 21 UBAP2L 31114027 Cell Death Differ. 2019 PMC7205891 10.1038/s41418-019-0350-5 4 5 0 157 Humans|*Methylation|*Arginine|RNA Recognition Motif Proteins|DNA Helicases|Poly-ADP-Ribose Binding Proteins|RNA Helicases|Cytoplasmic Granules|messenger ribonucleoprotein|Ribonucleoproteins|Protein Arginine Methyltransferase|*Protein Processing, Post-Translational|RNA-Binding Proteins|Protein Binding|Cytoplasm|Amino Acid Sequence|Stress, Physiological|HeLa Cells|Cell Line, Tumor 21 ULK4 31841327 J. Am. Chem. Soc. 2019 PMC7261596 10.1021/jacs.9b10458 0 0 0 17 Humans|Animals|Protein-Serine-Threonine Kinases|*Schizophrenia|*Inhibition, Psychological|Mutations|Autophagy|Ulk4 protein, human 27 UPK1A 31522287 Virchows Arch. 2019 10.1007/s00428-019-02658-x 0 0 0 118 Humans|Adolescent|*Immunity, Innate|*Lymphoid Cells|Neoplasm Recurrence, Local|*Helper Cell|*Lymphoma|GATA3 protein, human|GATA3 Transcription Factor|B-Lymphocytes|Cell Differentiation|Flow Cytometry|Cells, Cultured|Gene Expression Regulation|Inflammation|*Phenotype|Tumor Microenvironment 66 UPK1A 31181195 Gen. Comp. Endocrinol. 2019 10.1016/j.ygcen.2019.06.003 0 0 0 118 Male|Rats|Animals|Escherichia coli|*Male Reproductive System|Epididymis|Testis|Sperm Maturation|*Uroplakin|Seminal Vesicles|Spermatozoa|Prostate|Spermatogenesis|mRNA|Immunity, Innate 66 UPK1A 30868438 In Vitro Cell. Dev. Biol. Anim. 2019 10.1007/s11626-019-00336-5 0 0 0 118 Swine|Animals|Proteomics|*Embryonic Stem Cells|*Cell Line|*Pancreas|*Pancreatic Duct|*Uroplakin|Cell Lineage|Cell Differentiation|Cell Culture Techniques|Exocrine Pancreas|Transcription Factors|Liver 66 UPK2 31273737 Methods Mol. Biol. 2019 10.1007/978-1-4939-9631-5_9 1 0 0 81 Mice|Animals|*Urothelium|*Mouse Embryonic Stem Cells|Cell Differentiation|Bladder|Stem Cells|Cells, Cultured|*Hematopoiesis|Signal Transduction 124 UPK2 31181195 Gen. Comp. Endocrinol. 2019 10.1016/j.ygcen.2019.06.003 0 0 0 81 Male|Rats|Animals|Escherichia coli|*Male Reproductive System|Epididymis|Testis|Sperm Maturation|*Uroplakin|Seminal Vesicles|Spermatozoa|Prostate|Spermatogenesis|mRNA|Immunity, Innate 124 UPK2 30670749 Sci Rep 2019 PMC6342925 10.1038/s41598-018-36720-6 0 1 0 81 Mice|Animals|*Urinary Bladder Neoplasms|*Hyperplasia|*Carcinoma, Transitional Cell|*Urologic Neoplasms|*Oncogenes|*Hepatocyte Nuclear Factor 3-alpha|Urothelium|*Tumorigenesis|Cell Transformation, Neoplastic|Mice, Transgenic|Gene Expression Regulation, Neoplastic 124 UPK2 30627578 Biomed Res Int 2019 PMC6304619 10.1155/2018/8693297 1 0 0 81 Humans|*Uroplakin II|*Urinary Bladder Neoplasms|*Antioxidants|Carcinoma, Transitional Cell|Biomarkers, Tumor|ROC Curve 124 URAD 31641447 Ecol Evol 2019 PMC6802028 10.1002/ece3.5490 0 2 0 3 *Carbon|Ecosystem|*Grassland|*Water|*Sand|Carbon Cycle|Soil|Climate Change|Seasons 55 URAD 31154510 Oecologia 2019 10.1007/s00442-019-04427-8 1 0 0 3 Animals|*Germination|Orchidaceae|Mycorrhizae|Symbiosis|*Forest|Seeds|Habitat|Endangered Species|Phylogeny 55 URAD 31075876 Bioengineering (Basel) 2019 PMC6630608 10.3390/bioengineering6020041 1 0 0 3 *Nanofibers|*Polymethyl Methacrylate|Tissue Engineering|Tissue Scaffolds|Biocompatible Materials|Cell Adhesion|Scanning Electron Microscopy|*Cytoskeleton|Cell Proliferation|Surface Properties|*B-Lymphocytes 55 URAD 30960018 Polymers (Basel) 2019 PMC6401689 10.3390/polym11010034 4 0 0 3 *Wettability|*Porosity|Hydrophobic and Hydrophilic Interactions|Surface Properties|Particle Size|*Dietary Fiber|Polymers 55 URAD 30838424 Eur. J. Clin. Pharmacol. 2019 10.1007/s00228-019-02650-z 3 0 0 3 fusafungin|*Antibiotics|*Pharmacovigilance|*Depsipeptides|Respiratory Tract Infections|Practice Patterns, Physicians'|Germany 55 URAD 30785905 PLoS ONE 2019 PMC6382110 10.1371/journal.pone.0211410 1 2 0 3 *Triticum|*Holidays|*Crops, Agricultural|Maize|Plant Diseases|Agriculture|India|Food Security|Bangladesh|Brassica rapa|Southern Asia 55 USP29 31878357 J Clin Med 2019 PMC7019889 10.3390/jcm9010052 0 0 0 22 Humans|*Parkinson Disease|parkin protein|Ubiquitin-Protein Ligases|MYBBP1A protein, human|*Nuclear Proteins|Dopaminergic Neuron|*Nucleocytoplasmic Transport Proteins|*Brain|Dopamine|Cell Death|Mutation|Deubiquitinating Enzymes|AIMP2 protein, human 34 USP29 30919279 Sci China Life Sci 2019 10.1007/s11427-018-9469-4 0 0 0 22 Male|Humans|Female|Mice|Animals|Spermatogenesis|*Fertility|Testis|Sperm Count|Infertility, Male|Sperm Motility|Mice, Knockout|CRISPR|Proteins 34 UTF1 31742474 J. Urol. 2019 10.1097/JU.0000000000000682 0 0 0 98 Male|Humans|*Sertoli Cells|*Testis|*Spermatogonia|Spermatogenesis|Azoospermia|Spermatozoa|*Transcriptome Analysis|*Inferior Colliculi|RNA, Messenger 110 UTF1 31671863 Int J Mol Sci 2019 PMC6862004 10.3390/ijms20215390 0 0 0 98 Humans|Male|Mice|Animals|Infant|Spermatogonia|*Adult Germline Stem Cells|Testis|Spermatogenesis|Seminiferous Tubules|ZBTB16 protein, human|Promyelocytic Leukemia Zinc Finger Protein|Cells, Cultured|Stem Cells|Stem Cell Transplantation|Xenotransplantation|Busulphan|*Boys|Cryopreservation|*Reproduction|UCHL1 protein, human|Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 110 UTF1 31364507 Toxicol Ind Health 2019 10.1177/0748233719862475 0 0 0 98 Male|Rats|Animals|coenzyme Q10|*Testis|*Rats, Wistar|bisphenol A|*Benzhydryl Compounds|*Phenols|Ubiquinone Q2|*Ubiquinone|Malondialdehyde|Antioxidants|Spermatozoa|Glutathione Peroxidase|Oxidative Stress|Superoxide Dismutase|Glutathione|Apoptosis 110 UTF1 31226129 PLoS ONE 2019 PMC6588212 10.1371/journal.pone.0218194 0 0 0 98 Humans|Male|Animals|*Macaque|*Testis|Spermatogonia|Spermatogenesis|Sertoli Cells|Cells, Cultured|Biomarkers|Primary Cell Culture|Cell Differentiation|*Population Dynamics 110 UTF1 31036718 Biochem. J. 2019 10.1042/BCJ20190057 0 1 0 98 Mouse Embryonic Stem Cells|Nanog Homeobox Protein|Octamer Transcription Factor-3|Transcription Factors|Embryonic Stem Cells|Cell Differentiation|Cells, Cultured 110 VASH1 31851940 Cell Rep 2019 10.1016/j.celrep.2019.11.074 2 0 0 222 Humans|*Tubulin|Phylogeny|Carrier Proteins|Cell Cycle Proteins|Angiogenic Proteins|Protein Conformation|Tyrosine|Crystallography, X-Ray|*Gene Expression|Trypanosoma brucei|SVBP protein, human|VASH1 protein, human|VASH2 protein, human 138 VASH1 31823788 Mol. Cancer 2019 PMC6902331 10.1186/s12943-019-1108-x 3 2 0 222 Humans|N(6)-methyladenosine|*Lung Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|*Adenosine|Epithelial-Mesenchymal Transition|Cell Movement|*Brain Neoplasms|Cell Proliferation|RNA Interference|3' Untranslated Regions|Cell Line, Tumor|Xenograft Model Antitumor Assays|Signal Transduction|VASH1 protein, human|Cell Cycle Proteins|MIRN143 microRNA, human 138 VASH1 31815666 Elife 2019 PMC6946400 10.7554/eLife.50094 1 0 0 222 Mice|Animals|*Internal Ribosome Entry Sites|*Trans-Acting Factor|*Myocytes, Cardiac|mRNA|Ribosomes|Protein Biosynthesis|*Hypoxia|Neovascularization, Pathologic 138 VASH1 31757187 Technol. Cancer Res. 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Lett. 2019 10.1016/j.neulet.2019.134633 1 4 0 222 *Retinal Ganglion Cells|kaempferol|*Kaempferols|Cell Survival|Apoptosis|Signal Transduction|Reactive Oxygen Species|Glucose|siRNA 138 VASH1 31712637 Gene Ther. 2019 10.1038/s41434-019-0108-1 0 4 0 222 Humans|Mice|Male|Animals|*RNA, Long Noncoding|Mice, Nude|*Upregulation|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|*Disease Progression|Cell Movement|Cell Line, Tumor|Tumorigenesis|*Genes, Regulator|*Prostate Cancer|RBMS3 protein, human|Trans-Activators|RNA-Binding Proteins|VASH1 protein, human|Cell Cycle Proteins 138 VASH1 31270470 Nat. Struct. Mol. Biol. 2019 10.1038/s41594-019-0254-6 2 1 0 222 tyrosine-tubulin|*Tubulin|Molecular Docking Simulation|tyrosyltubulin carboxypeptidase|*Carboxypeptidases|Carrier Proteins|*Cytoskeleton|Cell Cycle Proteins|Protein Conformation|Angiogenic Proteins|Tyrosine 138 VASH1 31235911 Nat. Struct. Mol. Biol. 2019 10.1038/s41594-019-0241-y 3 0 0 222 Humans|tyrosine-tubulin|*Tubulin|Carrier Proteins|Cell Cycle Proteins|Carboxypeptidases|Microtubules|Angiogenic Proteins|Tyrosine|Neurogenesis|Neurons|*Multienzyme Complexes|Protein Binding|SVBP protein, human 138 VASH1 31235910 Nat. Struct. Mol. Biol. 2019 PMC6609488 10.1038/s41594-019-0242-x 3 2 0 222 Humans|*Tubulin|SVBP protein, human|Carrier Proteins|Microtubule|Cell Cycle Proteins|Angiogenic Proteins|Tyrosine|tyrosyltubulin ligase|Peptide Synthases|Post-Translational Modifications|VASH1 protein, human|VASH2 protein, human 138 VASH1 31171830 Cell Res. 2019 PMC6796878 10.1038/s41422-019-0187-y 5 2 0 222 Humans|SVBP protein, human|Carrier Proteins|*Mitosis|Tubulin|Cell Cycle Proteins|Microtubule|Protein Conformation|Angiogenic Proteins|Crystallography, X-Ray|Tyrosine|Chromosome Segregation|VASH1 protein, human 138 VASH1 31091528 Neuroendocrinology 2019 10.1159/000499507 1 10 0 222 Rats|Animals|NGF protein, human|*Nerve Growth Factor|*Pheochromocytoma|*PC12 Cells|*Adrenal Gland Neoplasms|*Cell Differentiation|Neurite Outgrowth|Neurites|Signal Transduction|Mitogen-Activated Protein Kinase 3|Cell Survival|Proto-Oncogene Proteins c-akt|Phosphorylation|Neurons|Prolactin 138 VASH1 31091125 Am. J. Physiol. Renal Physiol. 2019 10.1152/ajprenal.00045.2019 0 0 0 222 Male|Mice|Animals|*Cisplatin|Endothelial Cells|*Acute Kidney Injury|*Kidney|Mice, Inbred C57BL|Apoptosis|Fibrosis|Chronic Kidney Disease|Capillaries|Disease Models, Animal 138 VASH1 30938218 Stem Cells Dev. 2019 10.1089/scd.2019.0014 2 2 0 222 Humans|EZH2 protein, human|*Enhancer of Zeste Homolog 2|H19 long non-coding RNA|*RNA, Long Noncoding|*Mesenchymal Stem Cells|*Amnion|*Genes, Tumor Suppressor|*Neovascularization, Pathologic|Human Umbilical Vein Endothelial Cells|Coculture|Medium, Conditioned|Cell Proliferation|Cell Line, Tumor|Angiogenesis Factor|*Genes, Regulator|VASH1 protein, human|Cell Cycle Proteins 138 VASH1 30623077 Health Sci Rep 2019 PMC6266348 10.1002/hsr2.40 2 0 0 222 Humans|*Lung Carcinoma, Non-Small-Cell|Endothelial Cells|Vascular Endothelial Growth Factor A|Lung Neoplasms|*Prognosis|Carcinoma, Renal Cell|Kidney Neoplasms|Biomarkers, Tumor|Cell Cycle Proteins|Neovascularization, Pathologic|Angiogenesis Inhibitors|*Transcription Factors|Tumor Microenvironment|VASH1 protein, human 138 VIPAS39 31479177 Hum. Mutat. 2019 10.1002/humu.23770 0 0 0 57 Humans|Arthrogryposis renal dysfunction cholestasis syndrome|*Arthrogryposis|*gamma-Glutamyltransferase|*Mutation, Missense|Retrospective Studies|Renal Insufficiency|*Cholestasis|*Phenotype|ABCB11 protein, human|Bile Salt Export Pump|Vesicular Transport Proteins|Heterozygote|Bile Acids|Mutation|*Syndrome|VPS33B protein, human 24 VIPAS39 31240160 JIMD Rep 2019 PMC6498830 10.1002/jmd2.12027 0 0 0 57 Arthrogryposis|Cholestasis|Heterozygote|Vesicular Transport Proteins|Mutations|Renal Insufficiency|Phenotype|Syndrome 24 VIPAS39 30716086 PLoS ONE 2019 PMC6361458 10.1371/journal.pone.0211647 1 22 0 57 Humans|Ehlers-Danlos syndrome type 1|*Ehlers-Danlos Syndrome|*Transcriptome|Type V Collagen|*Fibroblasts|Skin Abnormalities|*Transcriptome Profiling|Extracellular Matrix|FN1 protein, human|Fibronectin|Collagen|Connective Tissues|Cells, Cultured|Mutations|Haploinsufficiency|Integrins|Genes, cdc|Joint Hypermobility 24 VPS13B 31876103 Mol Genet Genomic Med 2019 PMC7057107 10.1002/mgg3.1108 1 0 0 123 Humans|Child|*Spastic Paraplegia, Hereditary|Spastic Ataxia|Optic Atrophy|Spinocerebellar Ataxias|Cohen syndrome|Intellectual Disability|Mutations|Heterozygote|Muscle Spasticity|Phenotypes|Pedigree|Parkinsonism|Developmental Disabilities|Fingers|Microcephaly|Muscle Hypotonia|Myopia|Obesity 75 VPS13B 31825161 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61435 0 0 0 123 Child|Female|Humans|Young Adult|Adult|Cohen syndrome|*Muscle Hypotonia|*Microcephaly|*Intellectual Disability|*Codon, Nonsense|Sexual Maturation|*Developmental Disabilities|*Retinal Degeneration|*Myopia|*Obesity|*Fingers|*Homozygote|Phenotype|Abnormalities, Multiple|Mutations|Facies|Vesicular Transport Proteins|Pedigree 75 VPS13B 31752730 BMC Med. Genet. 2019 PMC6873578 10.1186/s12881-019-0920-x 0 0 0 123 Humans|Child|Cohen syndrome|*Muscle Hypotonia|*Microcephaly|*Intellectual Disability|*Developmental Disabilities|*Retinal Degeneration|*Myopia|*Obesity|*Fingers|Vesicular Transport Proteins|Pedigree|Mutation|China|VPS13B protein, human 75 VPS13B 31580008 Acta Ophthalmol 2019 10.1111/aos.14255 0 0 0 123 Child|Humans|Cohen syndrome|*Retinitis Pigmentosa|*Retinal Degeneration|*Microcephaly|*Muscle Hypotonia|*Myopia|*Intellectual Disability|*Obesity|*Developmental Disabilities|*Fingers|*Eyes|Genes, Recessive|Electroretinography|Visual Field Tests|Eye Proteins|Pedigree|Phenotype|Visual Fields 75 VPS13B 31495077 Exp Neurobiol 2019 PMC6751864 10.5607/en.2019.28.4.485 1 0 0 123 Animals|Child|*Spatial Learning|Muscle Hypotonia|Microcephaly|Intellectual Disability|Developmental Disabilities|Vesicular Transport Proteins|Golgi Apparatus|Mutations|Retinal Degeneration|Disease Models, Animal 75 VPS13B 31444703 J. Mol. Neurosci. 2019 10.1007/s12031-019-01394-w 0 0 0 123 Humans|Child|Cohen syndrome|*Muscle Hypotonia|*Intellectual Disability|Iran|*Microcephaly|*Retinal Degeneration|*Myopia|*Developmental Disabilities|*Obesity|*Fingers|*Phenotypes|*Mutations|Pedigree|Abnormalities, Multiple|Vesicular Transport Proteins|Sequencing, Whole Exome|VPS13B protein, human 75 VPS13B 31240250 Commun Biol 2019 PMC6582147 10.1038/s42003-019-0454-y 7 0 0 123 Cattle|Male|Animals|*Bayes Theorem|*Phenotypes|Quantitative Trait Loci|Genome-Wide Association Study|Reproduction|Genotype|Milk|Polymorphism, Single Nucleotide|Genomics 75 VPS13B 31218450 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03192-4 0 0 0 123 Male|Mice|Animals|*Acrosome|*Golgi Apparatus|*Spermatogenesis|Spermatids|*Protein Transport|Sperm|Lysosome|Membrane Proteins|*Membrane 75 VPS13B 30962439 Nat Commun 2019 PMC6453939 10.1038/s41467-019-09617-9 6 13 0 123 Humans|*SNAREs|Syntaxin 13|*Protein Transport|Endosomes|Membrane Fusion|*Cell Movement|Transport Vesicles|Protein Binding|HeLa Cells|VPS13B protein, human|Vesicular Transport Proteins 75 VPS13B 30925032 Acta Ophthalmol 2019 10.1111/aos.14095 1 0 0 123 *Whole Exome Sequencing|*Retinal Dystrophies|Exome|DNA Mutational Analysis|Homozygote|Pedigree|Genes, Recessive|Retina|Electroretinography|Phenotype|Mutation|*Syndromes 75 VPS13B 30843084 J. Mol. Med. 2019 10.1007/s00109-019-01754-4 1 2 0 123 Child|Humans|Cohen syndrome|*Serpins|*Neutrophils|*Muscle Hypotonia|*Microcephaly|*Intellectual Disability|*Developmental Disabilities|*Retinal Degeneration|*Myopia|*Obesity|*Fingers|*Neutropenia|Mutations|Vesicular Transport Proteins|Apoptosis|VPS13B protein, human 75 VPS13B 30602132 Eur J Med Genet 2019 10.1016/j.ejmg.2018.12.015 0 0 0 123 Child|Child, Preschool|Humans|Cohen syndrome|*Intellectual Disability|*Whole Exome Sequencing|*DNA Copy Number Variations|*Siblings|Comparative Genomic Hybridization|Microcephaly|Hypotonia|Developmental Disabilities|Retinal Dystrophy|Exome|Myopia|Exons|Pedigree|Heterozygote|Mutations|Obesity|Sequence Deletion 75 VSX1 31822965 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03408-7 1 3 0 45 Mice|Animals|*Interneuron|Homeodomain Proteins|Motor Neurons|Cell Differentiation|Transcription Factors|Gene Expression Regulation, Developmental|Neurogenesis|Spinal Cord 115 VSX1 30816092 Biomed Khim 2019 10.18097/PBMC20196501009 1 0 0 45 Humans|*Keratoconus|*Genetic Markers|Genetic Susceptibility|Genetic Association Studies|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Cornea|Genotype|Eye Proteins|Case-Control Studies|Mutations|Russia|MAP3K19 protein, human|MAP Kinase Kinase Kinases 115 VSX1 30809473 Int J Ophthalmol 2019 PMC6376235 10.18240/ijo.2019.02.03 0 0 0 45 Humans|*Keratoconus|*Genes, Homeobox|Corneal Stroma|Cornea|Fibroblasts|RNA, Messenger|Actins|Biomarkers 115 VTCN1 31722750 J Immunother Cancer 2019 PMC6854706 10.1186/s40425-019-0752-4 1 0 0 317 *Nasopharyngeal Carcinoma|*Prognosis|B7-H1 Antigen|V-Set Domain-Containing T-Cell Activation Inhibitor 1|Nasopharyngeal Neoplasms|Neoplasm Staging|Biomarkers, Tumor|Kaplan-Meier Estimate 232 VTCN1 31679792 Pathol. 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Sci. 2019 PMC6907741 10.1016/j.tips.2019.09.008 0 0 0 317 Humans|Animals|VTCN1 protein, human|V-Set Domain-Containing T-Cell Activation Inhibitor 1|CD274 protein, human|B7-H1 Antigen|Cancers|Lymphocyte Activation|Antibodies, Monoclonal|Autoimmune Diseases 232 VTCN1 31555486 ESMO Open 2019 PMC6735664 10.1136/esmoopen-2019-000554 0 1 0 317 Male|CD274 protein, human|B7-H1 Antigen|V-Set Domain-Containing T-Cell Activation Inhibitor 1|Lymphocyte Activation|Cancers|Antibodies, Monoclonal|Tumor Immune Evasion|Autoimmune Diseases|Antineoplastic Agents, Immunological|Cell Proliferation|Autoimmunity 232 VTCN1 31282407 Cancer Biomark 2019 10.3233/CBM-190067 0 0 0 317 *CA-19-9 Antigen|*Prognosis|*Pancreatic Cancer|V-Set Domain-Containing T-Cell Activation Inhibitor 1|Biomarkers, Tumor|Kaplan-Meier Estimate 232 VTCN1 31222843 Cancer Sci. 2019 PMC6676111 10.1111/cas.14113 5 0 0 317 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|CD274 protein, human|B7-H1 Antigen|*Mutations|Progression-Free Survival|Antineoplastic Agents, Immunological|Biomarkers, Tumor|CTLA4 protein, human|CTLA-4 Antigen|Immunotherapy|Gene Expression Regulation, Neoplastic|Cohort Studies 232 VTCN1 31137925 Int J Mol Sci 2019 PMC6567280 10.3390/ijms20102606 1 0 0 317 Humans|*Lupus Nephritis|*Biomarkers|Lupus Erythematosus, Systemic|Kidneys|IGBP1 protein, human|*Intracellular Signaling Peptides and Proteins|Disease Progression|Severity of Illness Index|ELISA|Immunoglobulins 232 VTCN1 31128028 J BUON 2019 1 0 0 317 Humans|Female|*Proliferating Cell Nuclear Antigen|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|V-Set Domain-Containing T-Cell Activation Inhibitor 1|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Lymphatic Metastasis 232 VTCN1 30864554 Iran J Immunol 2019 10.22034/IJI.2019.39405 1 0 0 317 Humans|*Lupus Erythematosus, Systemic|Lupus Nephritis|V-Set Domain-Containing T-Cell Activation Inhibitor 1|Enzyme-Linked Immunosorbent Assay|Immune Tolerance 232 VTCN1 30854414 Bladder Cancer 2019 PMC6401562 10.3233/BLC-180204 2 1 0 317 Humans|Dogs|Animals|*Urinary Bladder Neoplasms|VTCN1 protein, human|*V-Set Domain-Containing T-Cell Activation Inhibitor 1|Carcinoma, Transitional Cell|Lymphocyte Activation|Immune Tolerance 232 VTCN1 30850021 J Immunother Cancer 2019 PMC6408760 10.1186/s40425-019-0540-1 10 5 0 317 Humans|CD274 protein, human|*B7-H1 Antigen|*Small Cell Lung Carcinoma|Lung Neoplasms|Prognosis|Lymphocytes, Tumor-Infiltrating|B7 Antigens|Biomarkers, Tumor 232 VTCN1 30813210 Medicine (Baltimore) 2019 PMC6407991 10.1097/MD.0000000000014663 2 4 0 317 CD274 protein, human|B7-H1 Antigen|Costimulatory Molecules, B7|Lymphocytes, Tumor-Infiltrating|V-Set Domain-Containing T-Cell Activation Inhibitor 1|*Carcinogenesis|*Disease Progression|CD8-Positive T-Lymphocytes|Prognosis|Biomarkers, Tumor 232 VTCN1 30737243 Clin. Cancer Res. 2019 10.1158/1078-0432.CCR-17-3123 6 0 0 317 Humans|*Antibodies, Bispecific|*Single-Chain Antibodies|CD3 Complex|Xenograft Model Antitumor Assays|T-Lymphocytes|Tumor Cells, Cultured 232 WDFY4 31754022 Genome Res. 2019 PMC6886503 10.1101/gr.251983.119 1 0 0 12 Gene Expression Regulation, Fungal|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Gene Regulatory Networks|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Transcription, Genetic|Models, Genetic|Transcription Factors|Algorithms 20 WDFY4 31415030 Curr Opin Rheumatol 2019 PMC6791565 10.1097/BOR.0000000000000652 0 0 0 12 Humans|*Idiopathic Inflammatory Myopathies|Polymyositis|HLA-DRB1 Chains|Genetic Predisposition to Disease|Haplotypes|Alleles|Autoantibodies|European Continental Ancestry Group|Phenotype 20 WDFY4 31122248 BMC Med Genomics 2019 PMC6533173 10.1186/s12920-019-0503-x 1 0 0 12 Humans|*Encephalitis, Tick-Borne|*Exome|Russia|Tick-Borne Encephalitis Virus|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Alleles|Genotype|*Encephalitis, Viral|*Flavivirus Infections 20 WFDC1 31675536 Nutr Res 2019 10.1016/j.nutres.2019.07.006 0 0 0 69 Male|Rats|Animals|*Wheat Bran|fructooligosaccharide|ROS1 protein, human|Protein-Tyrosine Kinases|*Fermentation|Proto-Oncogene Proteins|*Rats, Inbred F344|*Oligosaccharides|*Colon|*Intestinal Mucosa|*Apoptosis|*Oncogenesis|*Cell Transformation, Neoplastic|*Cell Proliferation|Colonic Neoplasms|*Signal Transduction|Carcinogens|CASP8 protein, human 42 WFDC1 31242033 Arterioscler. Thromb. Vasc. Biol. 2019 PMC6597191 10.1161/ATVBAHA.119.312388 1 4 0 69 Animals|Mice|Endothelial Cells|Wnt Pathway|Axin Protein|beta Catenin|*Catenins|Blood-Brain Barrier|Central Nervous System|*Extracellular Matrix|*Organogenesis 42 WHAMM 31824651 F1000Res 2019 PMC6880267 10.12688/f1000research.18669.1 0 0 0 1784 *Actins|Arp2-3 Complex|Filaments, Actin|*Cell Motility|Cytoskeleton|Microfilament Proteins|Formins 33 WHAMM 31704058 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111709 0 2 0 1784 Humans|myotubularin|*Protein Tyrosine Phosphatases, Non-Receptor|*Golgi Apparatus|*Protein Transport|Phosphatidylinositol Phosphates|TYRP1 protein, human|*Membrane Glycoproteins|Endosomes|Autophagy|Signal Transduction|Cell Line|*Cell Movement|WNT3A protein, human|Wnt3A Protein 33 WHAMM 31420534 Nat Commun 2019 PMC6697732 10.1038/s41467-019-11694-9 1 2 0 1784 *Actins|*Polymerization|*Lysosome|Microtubules|Microtubule-Associated Proteins|Actin-Related Protein 2-3 Complex|*Autophagosomes|Autophagy|Membrane Proteins 33 WHAMM 30760334 Clin Epigenetics 2019 PMC6375219 10.1186/s13148-019-0614-4 2 0 0 1784 Humans|*Cross-Sectional Studies|United Kingdom|*Epigenetic|CpG Islands|Epigenesis, Genetic|DNA Methylation|Twins, Monozygotic|Genome-Wide Association Study|*Periodontitis 33 WISP2 31788071 Oncol Lett 2019 PMC6865154 10.3892/ol.2019.10944 0 4 0 13 Humans|*Up-Regulation|*Cell Proliferation|*Lung Cancer|Long Non-Coding RNA|Carcinoma, Non-Small-Cell Lung|*Transcriptional Activation|MicroRNAs|Gene Expression Regulation, Neoplastic|A549 Cells|Cell Movement|CCND1 protein, human|Cyclin D1|Cell Line, Tumor|Carcinogenesis|AKT1 protein, human|Protein Kinase B|Adenocarcinoma|RNA, Anti-Sense 117 WISP2 31463037 Bone Joint Res 2019 PMC6691371 10.1302/2046-3758.87.BJR-2018-0297.R1 1 0 0 13 Humans|*Transcriptome|Cartilage, Articular|*Knee Joint|RNA, Long Noncoding|Osteoarthritis, Knee|Chondrocytes|mRNA|Gene Expression Profiling|*Transcriptome Sequencing, Whole 117 WISP2 31437074 Growth Factors 2019 10.1080/08977194.2019.1652400 0 5 0 13 CCN5 protein, human|*CCN Intercellular Signaling Proteins|*Repressor Proteins|*Islet Cell|Cell Proliferation|TYRP1 protein, human|*Membrane Glycoproteins|Signal Transduction|CCND1 protein, human|Cyclin D1|Upregulation|*Neuroendocrine Cells|Recombinant Proteins 117 WISP2 31346457 Bone Joint Res 2019 10.1302/2046-3758.86.BJR-2018-0297.R1 2 0 0 13 Humans|*Transcriptome|Cartilage, Articular|*Knee Joint|RNA, Long Noncoding|Osteoarthritis, Knee|Chondrocytes|mRNA|Gene Expression Profiling|*Transcriptome Sequencing, Whole 117 WISP2 31208847 Anim. 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Rep. 2019 PMC6702357 10.1042/BSR20190827 2 0 0 139 35 XPO4 31083992 Inorg Chem 2019 10.1021/acs.inorgchem.9b00715 0 0 0 139 Colors|Nickel|Pigments, Inorganic|Cobalt|Colorimetry|basic fuchsin|Rosaniline Dyes 35 XPO4 31023722 J. Cell Biol. 2019 PMC6548137 10.1083/jcb.201812093 2 1 0 139 *Active Transport, Cell Nucleus|Exportins|beta Karyopherins|ran GTP-Binding Protein|Cell Nucleus|Cytoplasm|Ubiquitin-Conjugating Enzymes|Amino Acid Sequence 35 XPO4 30762053 Nanoscale 2019 10.1039/c8nr10224d 0 0 0 139 Lithium|Electric Power Supplies|Electrodes|Electrochemical Techniques|Oxides|Nanostructures 35 Y_RNA 31416454 J. Biomed. Sci. 2019 PMC6694579 10.1186/s12929-019-0553-6 1 1 0 0 Humans|Dogs|Animals|*Influenza, Human|*Exosomes|*Virus Replication|Influenza A Virus, H1N1 Subtype|Influenza A Virus, H3N2 Subtype|Influenza A Virus, H5N1 Subtype|MicroRNAs|Host-Pathogen Interactions|Viral Proteins|A549 Cells|Madin Darby Canine Kidney Cells|HEK293 Cells 117 Y_RNA 31084369 Crit. Rev. Biochem. Mol. 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Microbiol. 2019 10.1111/1462-2920.14831 1 0 0 103 *Flavonoids|*Rhizobiaceae|Citrus|Plant Diseases|Bacterial Proteins 37 YBEY 31465450 PLoS Genet. 2019 PMC6738653 10.1371/journal.pgen.1008346 5 3 0 103 *Staphylococcus aureus|*Guanosine Pentaphosphate|RNA, Ribosomal, 16S|Ribosome|Escherichia coli Proteins|*Protein Binding|Escherichia coli|Ribosomal Proteins|Gene Expression Regulation, Bacterial|GTPases|guanosine 3',5'-polyphosphate synthetases|Ligases|Bacterial Proteins|alpha-sarcin|Endoribonucleases|GTP-Binding Proteins|RNA-Binding Proteins|*Staphylococcal Infections 37 YBEY 31106970 J. Cell. Mol. Med. 2019 PMC6584519 10.1111/jcmm.14315 1 2 0 103 Humans|Female|*Polymorphism, Single Nucleotide|*Leukocytes, Mononuclear|Genome-Wide Association Study|Quantitative Trait Loci|DNA Methylation|mRNA|*Leukocytes|Phenotype|*Mononuclear Phagocyte System 37 YBEY 30885931 J. 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Monit. 2019 PMC6926093 10.12659/MSM.920381 0 0 0 76 Humans|*Methylation|*Prognosis|*Colon Cancer|*Adenocarcinoma|RBM15 protein, human|RNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Clustering|RNA, Messenger|Methyltransferases|RNA|Colorectal Neoplasms|Signal Transduction|Adenosine|Colon|YTHDC2 protein, human|Adenosine Triphosphatases 34 YTHDC2 31767846 Nat Commun 2019 PMC6877647 10.1038/s41467-019-13317-9 2 2 0 76 Protein Biosynthesis|RNA, Messenger|RNA Helicases|Adenosine 34 YTHDC2 31720080 Am J Cancer Res 2019 PMC6834477 8 0 0 76 Head and Neck Squamous Cell Carcinoma|Prognosis|Head and Neck Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Transcriptome|Kaplan-Meier Estimate 34 YTHDC2 31706844 Biochem. Pharmacol. 2019 10.1016/j.bcp.2019.113697 0 6 0 76 *Methylation|*Adenosine|RNA|Methyltransferases|RNA, Messenger|*Protein Processing, Post-Translational 34 YTHDC2 31472957 Biochem. Biophys. Res. 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Physiol. 2019 10.1002/jcp.28416 2 10 0 98 Rats|Animals|*Mesenchymal Stem Cells|*RNA, Long Noncoding|Osteogenesis|*Interleukin 1|*Wnt Signaling Pathway|*Cell Differentiation|beta Catenin|*Bone Regeneration|*Catenins|Cell Proliferation|Cells, Cultured|Upregulation|Osteocalcin|Transcription Factor|Gene Expression Regulation 21 ZBED3 30805970 J. Cell. Biochem. 2019 10.1002/jcb.28498 1 14 0 98 *Lung Cancer|*Cell Proliferation|Transcription Factors|DNA-Binding Proteins|Catenins|Binding Site|Signal Transduction|*Finger 21 ZBED3 30667367 Horm Mol Biol Clin Investig 2019 10.1515/hmbci-2018-0052 0 0 0 98 Humans|*Prediabetic State|*Metabolic Syndrome|*Ghrelin|Cross-Sectional Studies|Adiposity|Waist Circumference|Biomarkers|Body Mass Index|Obesity|Lipid Accumulation Product|Zinc Fingers|ZBED3 protein, human|DNA-Binding Proteins|Transcription Factors 21 ZBTB18 31830750 Cytogenet. Genome Res. 2019 10.1159/000504424 0 0 0 323 Humans|*Microcephaly|*Corpus Callosum|*Seizures|Agenesis of Corpus Callosum|Chromosome Deletion|*Leukoaraiosis|Syndrome|*Chromosome Structures 41 ZBTB18 31238879 J Neurodev Disord 2019 PMC6593513 10.1186/s11689-019-9270-4 0 0 0 323 Child|Humans|*Neurodevelopmental Disorders|Intellectual Disability|Exome|Developmental Disabilities|Phenotype 41 ZBTB18 31112317 Hum. Mutat. 2019 10.1002/humu.23803 0 0 0 323 Animals|Humans|Infant, Newborn|*Cerebral Cortex|*Neurons|Repressor Proteins|Zinc Finger|Cell Movement|Gene Expression Regulation|Brain|Protein Binding|Mutation|DNA|*Biophysical Phenomena 41 ZBTB18 30933949 Cytogenet. Genome Res. 2019 10.1159/000498998 0 0 0 323 Male|Humans|Female|Child, Preschool|Distal Trisomy 10q Syndrome|Trisomy|*Translocation, Genetic|Chromosome Banding|Karyotyping|Chromosome Deletion|In Situ Hybridization, Fluorescence|Chromosome Aberrations|Abnormalities, Multiple|Karyotype|Genetic Counseling|Phenotype|Father|Chromosomes, Human, Pair 10|SMYD3 protein, human|Histone-Lysine N-Methyltransferase 41 ZBTB18 30853971 Front Genet 2019 PMC6395382 10.3389/fgene.2019.00058 1 2 0 323 Humans|DNA Copy Number Variations|Microcephaly|Chromosome Deletion|Phenotype|Intellectual Disability 41 ZBTB18 30810905 Cerebellum 2019 10.1007/s12311-019-1009-y 0 0 0 323 *Medulloblastoma|*Ubiquitin|Cerebellar Neoplasms|Hedgehog Proteins|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|E3 Ligase|Protein Phosphatase 2A|Cell Line, Tumor 41 zbtb20 31821719 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61432 0 0 0 289 Child|Humans|Female|Primrose syndrome|*Intellectual Disability|*Abnormalities, Multiple|*Muscular Atrophy|*Ear Diseases|*Calcinosis|Developmental Disabilities|Mutations|Nerve Tissue Proteins|Phenotype|Transcription Factors|Comparative Genomic Hybridization|*Immunologic Deficiency Syndromes|Mutation, Missense|Genetic Predisposition to Disease|ZBTB20 protein, human 101 zbtb20 31570595 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6800326 10.1073/pnas.1906438116 0 6 0 289 Mice|Animals|*Prolactin|Encephalomyelitis, Autoimmune, Experimental|Th17 Cells|CD4-Positive T-Lymphocytes|Multiple Sclerosis|Central Nervous System|Mice, Inbred C57BL|T-Box Domain Proteins|Disease Models, Animal|Eomes protein, mouse 101 zbtb20 31556767 Artif Cells Nanomed Biotechnol 2019 10.1080/21691401.2019.1670188 0 9 0 289 *Stomach Neoplasms|*Cell Migration|NF-kappa B|Transcription Factors|Upregulation|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|RNA, Small Interfering 101 zbtb20 31539138 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201909_18864 2 8 0 289 *RNA, Long Noncoding|*Cell Proliferation|*Leukemia, Myeloid, Acute|MicroRNAs|Cell Movement|Cell Line, Tumor|*Cell Cycle 101 zbtb20 31321892 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61297 0 0 0 289 Humans|Male|Adult|Child, Preschool|Primrose syndrome|*Intellectual Disability|*Abnormalities, Multiple|*Muscular Atrophy|*Ear Diseases|*Calcinosis|*Phenotype|Facies|Genetic Association Studies|Mutation, Missense|Mutation|Transcription Factors|Nerve Tissue Proteins|Genetic Predisposition to Disease|Heterozygote|Brazil|ZBTB20 protein, human 101 zbtb20 31170943 BMC Cancer 2019 PMC6555720 10.1186/s12885-019-5739-5 0 0 0 289 Child|Humans|*Decision Trees|*Glioma|Ganglioglioma|Astrocytoma|RNA, Micro|Brain Neoplasms|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Real-Time Polymerase Chain Reaction 101 zbtb20 31130955 Front Immunol 2019 PMC6510054 10.3389/fimmu.2019.00965 3 0 0 289 *Plasma Cells|Humoral Immunity|CD28 Antigens|B7-1 Antigen|Cells, Stromal|Cell Survival|Signal Transduction|Cell Microenvironment|Antigen 101 zbtb20 30982661 Dev. Cell 2019 10.1016/j.devcel.2019.03.012 3 0 0 289 Mice|Animals|*Growth Hormone|*Prolactin|*RNA, Long Noncoding|*Pituitary Hormones, Anterior|*Human Growth Hormone|Pituitary Gland, Anterior|Transcription Factors|MicroRNAs|Pituitary Gland|RNA, Messenger|*Protein Binding|Pituitary Diseases|Cells, Cultured 101 zbtb20 30919954 J. Comp. Neurol. 2019 PMC6879308 10.1002/cne.24688 1 0 0 289 Animals|Finches|Amygdala|Vocalization, Animal|Neural Pathways|Prosencephalon 101 zbtb20 30852025 J. Dairy Sci. 2019 10.3168/jds.2018-15906 2 0 0 289 Cattle|Animals|Female|Humans|*Mycobacterium avium paratuberculosis|*Paratuberculosis|Cattle Diseases|Breeding|Genome-Wide Association Study|Quantitative Trait Loci|ELISA|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|*Gastrointestinal Diseases|Linear Models|SNX1 protein, human|Sorting Nexins 101 zbtb20 30810905 Cerebellum 2019 10.1007/s12311-019-1009-y 0 0 0 289 *Medulloblastoma|*Ubiquitin|Cerebellar Neoplasms|Hedgehog Proteins|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|E3 Ligase|Protein Phosphatase 2A|Cell Line, Tumor 101 ZBTB38 30984241 Front Genet 2019 PMC6448050 10.3389/fgene.2019.00251 5 0 0 165 Animals|*Ictaluridae|*Chromosome Mapping|Genetic Linkage|Quantitative Trait Loci|*Phenotype|Microsatellite Repeats|Sequence Analysis, DNA|Polymorphism, Single Nucleotide|Aquiculture|*Biological Phenomena 43 ZBTB38 30697495 PeerJ 2019 PMC6348090 10.7717/peerj.6352 1 1 0 165 Humans|*Neuroblastoma|*Transcriptome Profiling|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Proliferation|Cell Line, Tumor|Transcription Factor|Cell Cycle|Apoptosis|ZBTB38 protein, human|Repressor Proteins 43 ZC3H12D 31290567 Electrophoresis 2019 10.1002/elps.201900118 0 0 0 498 Female|*DNA Methylation|CpG Islands|Epigenetic|Forensic Genetics|hydrogen sulfite|Sulfites|Semen|Sequence Analysis, DNA|DNA|Saliva|Genetic Markers|Body Fluids|PCR, Multiplex|cytidylyl-3'-5'-guanosine|Dinucleoside Phosphates|Epithelium 20 ZC3H12D 30988100 RNA 2019 PMC6573786 10.1261/rna.071381.119 2 5 0 498 Humans|RNase|RNA Stability|Interleukin 6|mRNA|3' Untranslated Regions|Transcription Factors|Immunoprecipitation|Inflammation|HeLa Cells|ZC3H12A protein, human 20 ZC3H13 31823961 Med. Sci. Monit. 2019 PMC6926093 10.12659/MSM.920381 0 0 0 158 Humans|*Methylation|*Prognosis|*Colon Cancer|*Adenocarcinoma|RBM15 protein, human|RNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Clustering|RNA, Messenger|Methyltransferases|RNA|Colorectal Neoplasms|Signal Transduction|Adenosine|Colon|YTHDC2 protein, human|Adenosine Triphosphatases 22 ZC3H13 31532791 PLoS ONE 2019 PMC6750603 10.1371/journal.pone.0222336 0 0 0 158 Humans|*Inflammatory Breast Cancer|Triple Negative Breast Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|Gene Expression Profiles 22 ZC3H14 31406157 Sci Rep 2019 PMC6691113 10.1038/s41598-019-48186-1 0 0 0 116 Humans|*Carotid Intima-Media Thickness|*Genetic Linkage|*Atherosclerosis|Quantitative Trait Locus|Carotid Artery Diseases|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Pedigree|*Hispanic Americans|Phenotype|Sequence Analysis, DNA|Exons|PRIMA1 protein, human|Membrane Proteins|Nerve Tissue Proteins|SPATA7 protein, human 23 ZDHHC9 31747610 Cell Rep 2019 10.1016/j.celrep.2019.10.065 1 1 0 61 Animals|Humans|Mice|*Intellectual Disability|*X-Linked Gene|Synapses|Mice, Knockout|Hippocampus|*Neurogenesis|Inhibitory Postsynaptic Currents|Palmitoylation|Epilepsy|Mutations|Acyltransferases|Dendrites|ZDHHC9 protein, human 30 ZDHHC9 31700678 NPJ Genom Med 2019 PMC6828700 10.1038/s41525-019-0101-z 0 0 0 61 Humans|*Cerebral Palsy|Sequencing, Next-Generation|Genomics|Sequence Analysis, DNA|Genetic Predisposition to Disease|Heterogeneities, Genetic|Genetic Variation|Mutation|*Databases, Genetic|Cohort Studies 30 ZDHHC9 31639257 Hum Brain Mapp 2019 PMC7268087 10.1002/hbm.24820 2 0 0 61 Humans|Magnetoencephalography|Brain Mapping|Brain|Neural Pathways|Nerve Net|*Disorder, Neurodevelopmental|Magnetic Resonance Imaging|Cognition|ZDHHC9 protein, human|Acyltransferases 30 ZDHHC9 31512789 J. Cell. Biochem. 2019 10.1002/jcb.29390 0 0 0 61 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Prognosis|Disease-Free Survival|Biomarkers, Tumor|Kaplan-Meier Estimate|Gene Expression Regulation, Neoplastic|RNA, Messenger|Disease Progression 30 ZDHHC9 30631761 Front Pediatr 2019 PMC6315160 10.3389/fped.2018.00391 5 0 0 61 30 ZFAT 31813799 Mol. Ther. 2019 PMC7001006 10.1016/j.ymthe.2019.11.015 0 15 0 28 *MicroRNAs|*RNA-Binding Proteins|*Glioma|Long Non-Coding RNA|Cell Proliferation|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Movement|Cell Line, Tumor|Downregulation 70 ZFAT 31723199 Sci Rep 2019 PMC6853925 10.1038/s41598-019-53102-8 1 0 0 28 Horses|Animals|*Transcriptome|Republic of Korea|*Genome|Breeding|*Transcriptome Analyses|SNPs|Oligonucleotide Array Sequence Analysis|Base Sequence|Phenotype 70 ZFAT 31626392 J Appl Res Intellect Disabil 2019 10.1111/jar.12674 0 0 0 28 Child|Adult|Humans|*Intellectual Disability|Disabled Children 70 ZFAT 31533623 BMC Genomics 2019 PMC6751660 10.1186/s12864-019-6071-9 5 0 0 28 Animals|Cattle|*Benchmarking|Breeding|Quantitative Trait Loci|Phenotype|Genome-Wide Association Study|*Sequencing, Whole Genome|Meat|Polymorphism, Single Nucleotide|Genomics 70 ZFAT 31372812 Int Orthop 2019 10.1007/s00264-019-04378-y 0 0 0 28 Humans|*Arthroplasty, Replacement, Knee|*Obesity, Morbid|Knee Osteoarthritis|Knee Joint|Postoperative Complications|Treatment Outcome|Body Mass Index|Risk Factors 70 ZFAT 31366551 Anticancer Res. 2019 10.21873/anticanres.13625 1 1 0 28 Mice|Animals|*Cells, Erythroid|Erythropoiesis|Cell Differentiation|Transcription Factors|Liver|ZFAT protein, mouse 70 ZFAT 31270553 Int Urogynecol J 2019 10.1007/s00192-019-04039-z 0 0 0 28 Humans|Female|*Pelvic Organ Prolapse|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|China 70 ZFAT 31261764 Genes (Basel) 2019 PMC6679042 10.3390/genes10070491 3 0 0 28 Horses|Animals|*Breeding|*Genome|*Homozygote|Genetics, Population|Natural Selection|Inbreeding|Genotype|Phenotype|Genomics|Polymorphism, Single Nucleotide 70 ZFAT 31242935 Clin Epigenetics 2019 PMC6595585 10.1186/s13148-019-0692-3 1 0 0 28 Animals|Humans|Female|Pregnancy|Genomic Imprinting|*Alleles|Placenta|Epigenesis, Genetic|DNA Methylation|Fetal Growth Retardation|Insulin-Like Growth Factor II|Pre-Eclampsia|Fetal Growth|Transcriptome|Gestational Diabetes 70 ZFAT 31199540 Anim. Genet. 2019 PMC6617995 10.1111/age.12797 5 0 0 28 Horses|Animals|Genetics, Population|Genome|Homozygote|Breeding|Inbreeding|Genotype|Genetic Variation|Phenotype|*Body Size|Polymorphism, Single Nucleotide 70 ZFAT 30836944 Genet. Sel. Evol. 2019 PMC6402105 10.1186/s12711-019-0452-z 4 1 0 28 Animals|Cattle|*Haplotypes|*Genes, Lethal|*Phenotype|Breeding|Quantitative Trait Loci|Genotype|Genome-Wide Association Study|Homozygote|Polymorphism, Single Nucleotide 70 zfhx4 31645542 Oncogenesis 2019 PMC6811597 10.1038/s41389-019-0167-6 0 2 0 66 *Lung Adenocarcinoma|Long Non-Coding RNA|MicroRNAs|mRNA|TWIST1 protein, human|*Twist-Related Protein 1|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|*Nuclear Proteins|*Neoplastic Processes|Pseudogenes|Upregulation|RNAs, Circular|Lung Neoplasms|Cell Proliferation 26 zfhx4 30794281 Inflamm. Bowel Dis. 2019 10.1093/ibd/izz020 0 0 0 66 Humans|*Colitis, Ulcerative|*Whole Exome Sequencing|*Colorectal Cancer|Crohn Disease|*Chinese|Carcinogenesis|Mutation|Cell Transformation, Neoplastic|*Colonic Neoplasms 26 ZFP36L2 31745208 Sci Rep 2019 PMC6864069 10.1038/s41598-019-53894-9 0 0 0 866 Humans|*Cyclin|*Tumor Suppressor Protein p53|*Cell Proliferation|*Proliferating Cell Nuclear Antigen|Tristetraprolin|*Cell Cycle Checkpoints|Nuclear Proteins|Transcription Factors|Cell Differentiation|HEK293 Cells|Cyclin D|ZFP36L1 protein, human|Butyrate Response Factor 1 71 ZFP36L2 31048690 Nat Commun 2019 PMC6497673 10.1038/s41467-019-09644-6 6 0 0 866 Humans|*Stomach Neoplasms|*Prognosis|*Mutations|Oncogenes|*Sequencing, Whole Genome|CDH1 protein, human|Cadherin 1|Tumorigenesis|Gene Expression Regulation, Neoplastic|CCND1 protein, human|Cyclin D1|ERBB2 protein, human|Receptor, ErbB-2|Genomics|DNA Copy Number Variations|Antigens, CD 71 ZFP36L2 30993080 J Biol Res (Thessalon) 2019 PMC6449998 10.1186/s40709-019-0094-x 5 0 0 866 Humans|Male|Female|*Alopecia|Hair Follicle|beta Catenin|Cell Differentiation|*Biomarkers|Signal Transduction 71 ZFP36L2 30887516 J Surg Oncol 2019 10.1002/jso.25446 4 0 0 866 *Urinary Bladder Neoplasms|*Prognosis|Neoplasm Recurrence, Local|Kaplan-Meier Estimate|Biomarkers, Tumor|Area Under Curve|ROC Curve|Proportional Hazards Models|Gene Expression Profiling|Predictive Value of Tests 71 ZFP36L2 30621213 Int J Environ Res Public Health 2019 PMC6338918 10.3390/ijerph16010122 1 0 0 866 *Thyroid Gland|*Gene Regulatory Networks|*Toxicogenetics|Carcinogens|Polychlorinated Dibenzodioxins|*Carcinogenesis|Polychlorinated Biphenyls 71 ZFX 31751864 Parkinsonism Relat. Disord. 2019 10.1016/j.parkreldis.2019.11.007 0 0 0 224 Spastic Paraplegia Type 4|*Spastic Paraplegia, Hereditary|Spastin|Paraplegia|Mutation|Adenosine Triphosphatases|Pedigree 307 ZFX 31618668 Neurosci. Lett. 2019 10.1016/j.neulet.2019.134543 0 0 0 224 Humans|Familial paroxysmal dystonia|*Dystonia|*Brain Diseases|Sodium-Phosphate Cotransporter Proteins, Type III|*Basal Ganglia Diseases|*Calcinosis|*Nervous System Malformations|Mutations|Genetic Predisposition to Disease|Brain|Neurodegenerative Disorder 307 ZFX 31432109 Mol Med Rep 2019 PMC6755169 10.3892/mmr.2019.10539 0 5 0 224 Humans|*Imatinib Mesylate|*Homoharringtonine|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|K562 Cells|*Downregulation|Drug Resistance, Neoplasm|Gene Expression Regulation, Leukemic|Apoptosis|Signal Transduction|Cell Proliferation|Viability, Cell 307 ZFX 31412093 PLoS ONE 2019 PMC6693880 10.1371/journal.pone.0221170 1 0 0 224 Sheep|Cattle|Animals|*Livestock|Goats|Buffaloes|Real-Time Polymerase Chain Reaction|Gene Expression Profiling|Species Specificity|Transcriptomes|Algorithms|*Fibroblasts 307 ZFX 31310241 Aging (Albany NY) 2019 PMC6682511 10.18632/aging.102080 6 32 0 224 Humans|*Triple-Negative Breast Cancer|Long Non-Coding RNA|Cell Proliferation|*Signal Transduction|MicroRNAs|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|MIRN218 microRNA, human 307 ZFX 31172793 Epigenomics 2019 10.2217/epi-2018-0126 0 0 0 224 307 ZFX 31074773 Acta Biochim. Biophys. Sin. (Shanghai) 2019 10.1093/abbs/gmz041 1 2 0 224 Humans|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Apoptosis|*Gallbladder Neoplasms|*Phosphatidylinositol 3-Kinases|liensinine|*G2 Phase Cell Cycle Checkpoints|*Cell Line, Tumor|*Isoquinolines|*Phenols|Cell Proliferation|Phosphatidylinositol 3-Kinase|Viability, Cell|Signal Transduction|Xenograft Model Antitumor Assays 307 ZFX 31031962 Ecol Evol 2019 PMC6476764 10.1002/ece3.5093 1 0 0 224 Male|Female|Animals|*Diagnostic Tests, Routine|Sex Determination Analysis|Y Chromosome|Base Sequence|PCR|*Mammals|Sequence Analysis, DNA 307 ZFX 31027953 J Prosthet Dent 2019 10.1016/j.prosdent.2018.10.025 1 0 0 224 Humans|Female|Pregnancy|*Reproducibility of Results|Computer-Aided Design|Imaging, Three-Dimensional|Data Collection|Prenatal Care 307 ZFX 30944271 J. Vet. Med. Sci. 2019 PMC6541836 10.1292/jvms.18-0693 1 0 0 224 Male|Female|Republic of Korea|DNA Primers|Sex Determination Analysis|Polymerase Chain Reaction|DNA|Sequence Analysis, DNA 307 ZFX 30916255 Dental Press J Orthod 2019 PMC6434670 10.1590/2177-6709.24.1.38.e1-7.onl 0 0 0 224 *Dental Arch|Computer-Aided Design|Imaging, Three-Dimensional|Image Processing, Computer-Assisted|Software|*Data Collection 307 ZHX2 31880394 J. Cell. Mol. Med. 2019 PMC7011162 10.1111/jcmm.14906 1 0 0 190 Humans|3' Untranslated Region|*Chinese|Single Nucleotide Polymorphisms|MicroRNAs|Binding Sites|Genetic Predisposition to Disease|Case-Control Studies|*Pancreatic Cancer|Quantitative Trait Loci|RNA, Messenger|Luciferase 78 ZHX2 31740790 Cell Death Differ. 2019 PMC7206072 10.1038/s41418-019-0453-z 1 0 0 190 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Non-alcoholic Fatty Liver Disease|*Lipase|Homeodomain Proteins|Liver|Transcription Factors|Zinc Fingers|Hepatocytes|Cell Proliferation|Cell Line, Tumor|*Disease Progression|*Genes, Tumor Suppressor|Lipids 78 ZHX2 31683461 Cancer Biomark 2019 10.3233/CBM-190514 0 2 0 190 Humans|*MAPK, p38|*Apoptosis|*Lung Cancer|Cell Proliferation|Neoplasm Invasiveness|Cell Movement|Carcinoma, Non-Small-Cell Lung|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|MAP Kinase Signaling System|Cell Line, Tumor|Signal Transduction|ZHX2 protein, human|Transcription Factors|Homeodomain Proteins 78 ZHX2 31511211 Nan Fang Yi Ke Da Xue Xue Bao 2019 PMC6765599 10.12122/j.issn.1673-4254.2019.08.07 0 0 0 190 Rats|Mice|Animals|*Ganglia, Spinal|*Opioid Receptor|*Neuralgia|*Analgesics, Opioid|Hyperalgesia|Peripheral Nerve Injury|Rats, Sprague-Dawley|Disease Models, Animal|Zhx2 protein, mouse|Homeodomain Proteins 78 ZHX2 31321500 Mamm. Genome 2019 PMC6761023 10.1007/s00335-019-09811-6 1 1 0 190 Mice|Animals|*BALB C Mice|*Diet, High-Fat|*Lipids|Liver|Hepatocyte|Lipid Metabolism|major urinary proteins|Homeodomain Proteins|Transcription Factor|Gene Expression Regulation|Lipoprotein Lipase|Homeostasis|Gain, Weight|RNA, Messenger|Zhx2 protein, mouse 78 ZHX2 30787639 Cancer Manag Res 2019 PMC6368119 10.2147/CMAR.S184340 0 0 0 190 Humans|Homeodomain Proteins|Transcription Factors|Repressor Proteins|Biomarkers, Tumor|Kaplan-Meier Estimate|ZHX3 protein, human 78 ZHX2 30784286 Neoplasma 2019 10.4149/neo_2018_180806N593 0 0 0 190 *Carcinoma, Hepatocellular|*Liver Neoplasms|Homeodomain Proteins|Transcription Factors|HepG2 Cells|*Signal Transduction|Gene Expression Regulation, Neoplastic|Zinc Fingers|PTEN protein, human|PTEN Phosphohydrolase|Cell Line, Tumor|Promoter Regions, Genetic|Binding Sites|Chromatin Immunoprecipitation 78 ZIC4 31533147 Magy Onkol 2019 0 0 0 48 Middle Aged|Adult|Aged|Male|Humans|Female|Retrospective Studies|*Syndromes, Paraneoplastic Neurologic|Hashimoto's encephalitis|Encephalitis|Hashimoto Disease|Autoantibodies|amphiphysin|Nerve Tissue Proteins|Receptors, N-Methyl-D-Aspartate|Disorders, Neurological|*Laboratory Diagnoses 76 ZIC4 31427569 Cell Death Dis 2019 PMC6700115 10.1038/s41419-019-1845-1 0 1 0 48 Humans|*Glioblastoma|Glioma|Long Non-Coding RNA|Brain Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Migration|Upregulation|Cell Proliferation|Cell Line, Tumor|Apoptosis|RNA Binding Protein|Transfection|UPF1 protein, human|Trans-Activators|RNA Helicases|SHCBP1 protein, human|Shc Signaling Adaptor Proteins 76 ZIC4 31396565 Commun Biol 2019 PMC6677735 10.1038/s42003-019-0537-9 2 0 0 48 Humans|*Genome-Wide Association Study|Temporal Lobe|Occipital Lobe|Parietal Lobe|Frontal Lobe|Brain|Magnetic Resonance Imaging|*Genetic Loci|Hippocampus|Organ Size 76 ZIC4 31179511 Cerebellum 2019 10.1007/s12311-019-01048-y 0 0 0 48 Male|Humans|Child, Preschool|*Cerebellar Ataxia|neurochondrin|*Nerve Tissue Proteins|Glutamate Decarboxylase|Autoantibodies|immunoglobulin B|Homer 3|Purkinje Cells|Carrier Proteins|Immunotherapy|anticentromere antibody|Antibodies, Antinuclear 76 ZIC4 30995487 Cell Rep 2019 10.1016/j.celrep.2019.03.068 0 0 0 48 Animals|*Somites|Body Patterning|Zebrafish Proteins|Transcription Factors|Medaka|Gene Expression Regulation, Developmental|Trans-Activators|Hedgehog Proteins|HHIP protein, human|Carrier Proteins|Signal Transduction|Membrane Glycoproteins 76 ZIC4 30808286 BMC Genomics 2019 PMC6390542 10.1186/s12864-019-5530-7 0 3 0 48 Cattle|Animals|*Hamstring Muscles|Myogenesis|*Cell Differentiation|Satellite Cells, Skeletal Muscle|Gene Expression Profiling|*Gene Expression|Cells, Cultured|Breeding|*Paraspinal Muscles 76 ZIC4 30621721 J. Exp. Clin. Cancer Res. 2019 PMC6323715 10.1186/s13046-018-0990-1 10 4 0 48 Endothelial Cells|*Glioma|DICER1 protein, human|*Ribonuclease III|*DEAD-box RNA Helicases|*Neovascularization, Pathologic|Brain Neoplasms|MicroRNAs|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|RNA-Binding Proteins|*Morphogenesis 76 ZIC4 30617207 J. Neurosci. 2019 PMC6381258 10.1523/JNEUROSCI.1747-17.2018 0 3 0 48 Animals|Mice|*Heparitin Sulfate|Sulfotransferases|Fibroblast Growth Factor|*Cell Movement|*Astroglias|Extracellular Signal Regulated Kinases|Signal Transduction|*Neurogenesis|Prosencephalon 76 ZMIZ1 31833199 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61446 0 0 0 162 Child|Humans|*Siblings|ZMIZ1 protein, human|*Transcription Factors|Intellectual Disability|Developmental Disability|*Disorder, Neurodevelopmental|Exome|Dwarfism|Genetic Association Studies|Alleles|Mutation|Zinc Fingers|Syndrome|Seizures 65 ZMIZ1 31686520 Neoplasma 2019 10.4149/neo_2019_190213N116 0 3 0 162 Humans|Male|AR protein, human|Androgen Receptor|*Prostate|*Prostate Cancer|*Upregulation|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Alternative Splicing|Benign Prostatic Hyperplasia|Cell Line, Tumor|Apoptosis|RNA, Messenger|*Biomarkers 65 ZMIZ1 31562322 Nat Commun 2019 PMC6764957 10.1038/s41467-019-12267-6 1 0 0 162 Humans|Male|*Genome-Wide Association Study|Japan|Genetic Loci|Genetic Predisposition to Disease|*Prostate Cancer|Polymorphism, Single Nucleotide|Gene Frequency|Alleles|Asian Continental Ancestry Group|Genotype|European Continental Ancestry Group|Case-Control Studies|Risk Factors 65 ZMIZ1 31373686 Int. J. Cancer 2019 10.1002/ijc.32587 0 2 0 162 Humans|*Glioblastoma|*DNA Methylation|*Prognosis|DNA Modification Methylases|DNA Repair Enzymes|Brain Neoplasms|Isocitrate Dehydrogenase|Tumor Suppressor Proteins|Promoter Regions, Genetic|Biomarkers, Tumor|Mutation|ZMIZ1 protein, human|Transcription Factors 65 ZMIZ1 31096062 Mol. Immunol. 2019 10.1016/j.molimm.2019.04.006 0 0 0 162 Mice|Animals|*Introns|*Nested Genes|*Lymphocyte Activation|*Signal Transduction|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|CD3 Complex|CD4 Antigens|Cell Differentiation|Down-Regulation|Up-Regulation 65 ZMIZ1 30941131 Front Immunol 2019 PMC6433938 10.3389/fimmu.2019.00488 4 0 0 162 *Vitamin D|*Multiple Sclerosis|Receptors, Calcitriol|Calcitriol|Chromatin|*Vitamins|Enhancer Elements, Genetic|*Cholestanes|Acetylation|Protein Binding 65 ZMIZ1 30923172 J. Med. Genet. 2019 10.1136/jmedgenet-2018-105778 3 0 0 162 Humans|*Translocation, Genetic|*Phenotypes|Chromosome Breakpoints|Chromosome Aberrations|Chromosome Mapping|Sequencing, Next-Generation|Sequence Analysis, DNA|Whole Genome Sequencing|Intellectual Disability 65 ZMIZ1 30862794 Sci Rep 2019 PMC6414679 10.1038/s41598-019-40787-0 9 8 0 162 Humans|*Transcriptome|*Epigenome|*Muscle, Skeletal|*Epigenetic|*Hypertrophy|DNA Methylation|Resistance Training|Epigenesis, Genetic|Exercise|Transcriptome Analysis|Downregulation|Up-Regulation|ZMIZ1 protein, human|Transcription Factors|*Memory 65 ZMIZ1 30639322 Am. J. Hum. Genet. 2019 PMC6369415 10.1016/j.ajhg.2018.12.007 0 0 0 162 Animals|Mice|Child|ZMIZ1 protein, human|*Transcription Factors|*Disorder, Neurodevelopmental|Intellectual Disability|Developmental Disabilities|*Syndromes|Exome|Abnormalities, Multiple|Microcephaly|Mutations|Heterozygote|Mutation, Missense|Phenotype|Alleles|Nervous System Malformations 65 ZNF365 31669406 Exp. Eye Res. 2019 10.1016/j.exer.2019.107853 0 0 0 33 Genome-Wide Association Study|*Uveitis|Vogt-Koyanagi-Harada Disease|Genetic Predisposition|Behcet Disease|IL23R protein, human|Receptors, Interleukin|DNA Copy Number Variations|IL17F protein, human|IL-17F|HLA-DR Antigens|Case-Control Studies 57 ZNF469 31765226 Am J Sports Med 2019 10.1177/0363546519887955 0 0 0 19 Humans|*Dancing|*Prevalence|Ehlers-Danlos syndrome type 3|Ehlers-Danlos Syndrome|Joint Instability|Cross-Sectional Studies|Connective Tissue Diseases|*Connective Tissue 49 ZNF469 31482965 Arq Bras Oftalmol 2019 10.5935/0004-2749.20190087 1 0 0 19 *Whole Exome Sequencing|*Keratoconus|Gene Frequency|Pedigree|Exome|Heterozygote|Polymorphism, Single Nucleotide|Mutation, Missense|Transcription Factors|Brazil 49 ZNF469 31107761 Cornea 2019 PMC6612572 10.1097/ICO.0000000000002002 1 0 0 19 Female|Humans|*Keratoconus|*Corneal Perforation|*Cornea|Corneal Stroma|Riboflavin|Cross-Linking Reagents|Corneal Topography|Photosensitizing Agents|Corneal Pachymetry|Photochemotherapy|Collagen|Ultraviolet Rays|Visual Acuity|*Mutations|ZNF469 protein, human|Transcription Factors 49 ZNF469 31025659 Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2019 10.5507/bp.2019.017 0 0 0 19 Humans|Brittle cornea syndrome 1|*Skin Abnormalities|*Eye Abnormalities|*Joint Instability|Ehlers-Danlos Syndrome|DNA-Binding Proteins|Transcription Factors|Mutations|Pedigree|Polymorphism, Single Nucleotide|ZNF469 protein, human 49 ZNF469 30916512 J. Biol. Regul. Homeost. Agents 2019 0 0 0 19 *Keratoconus|*Superoxide Dismutase-1|*Superoxide Dismutase|Transcription Factors|Polymorphism, Single Nucleotide|Mutation|Zinc Fingers 49 ZNF469 30865045 Cornea 2019 10.1097/ICO.0000000000001828 0 2 0 19 Humans|Brittle cornea syndrome 1|Pakistan|*Skin Abnormalities|*Eye Abnormalities|*Joint Instability|Ehlers-Danlos Syndrome|DNA-Binding Proteins|Transcription Factors|Mutations|Pedigree|PRDM5 protein, human|ZNF469 protein, human 49 ZNF469 30816092 Biomed Khim 2019 10.18097/PBMC20196501009 1 0 0 19 Humans|*Keratoconus|*Genetic Markers|Genetic Susceptibility|Genetic Association Studies|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Cornea|Genotype|Eye Proteins|Case-Control Studies|Mutations|Russia|MAP3K19 protein, human|MAP Kinase Kinase Kinases 49 ZNF598 31532761 PLoS Biol. 2019 PMC6750593 10.1371/journal.pbio.3000396 1 0 0 133 Humans|Saccharomyces cerevisiae|*Ribosome|Saccharomyces cerevisiae Proteins|Protein Biosynthesis|mRNA Stability|mRNA|GTP-Binding Proteins|Adaptor Proteins, Signal Transducing|*Eukaryotic Cells|ZNF598 protein, human|Carrier Proteins|ASC1 protein, S cerevisiae|Hel2 protein, S cerevisiae|Ubiquitin-Protein Ligases 20 ZNF598 31433974 Cell Rep 2019 10.1016/j.celrep.2019.07.081 2 3 0 133 DDX58 protein, human|*DEAD Box Protein 58|*Innate Immune Response|Tripartite Motif Proteins|Interferon-Induced Helicase, IFIH1|E3 Ubiquitin Ligase|Ubiquitination|UBD protein, human|Ubiquitins|DEAD-box RNA Helicases|Signal Transduction|Transcription Factors|*Infection, Viral|RNA, Viral 20 ZNF598 30917308 Cell Rep 2019 10.1016/j.celrep.2019.03.006 2 1 0 133 ZFP36 protein, human|*Tristetraprolin|Rich Element, AU|RNA Stability|mRNA|*Gene Expression Regulation|*Signal Transduction|Cytokines|Inflammation 20 ZNF598 30770343 EMBO J. 2019 PMC6396152 10.15252/embj.2019101633 0 1 0 133 Humans|*Ribosome|UBB protein, human|*Ubiquitin|Ubiquitination|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Protein Biosynthesis|Ribosomal Protein|mRNA|Ubiquitin-Protein Ligases|HEK293 Cells|*Quality Control|ZNF598 protein, human|Carrier Proteins|Hel2 protein, S cerevisiae 20 ZNF644 31560770 Invest. Ophthalmol. Vis. Sci. 2019 10.1167/iovs.19-27921 1 0 0 140 Humans|*Cross-Sectional Studies|*Chinese|Myopia, Degenerative|*Genotype|Visual Acuity|Phenotype 20 ZNF644 31039430 Brain Behav. Immun. 2019 PMC6752960 10.1016/j.bbi.2019.04.039 1 0 0 140 Humans|*Stress Disorders, Post-Traumatic|*Syndrome|*Military Personnel|*Transcriptome|Depression|*Transcriptome Analysis|Comorbidity|ESCO1 protein, human|Acetyltransferases|RBaK protein, human|Repressor Proteins|ZNF644 protein, human|Transcription Factors|CREBZF protein, human|Basic-Leucine Zipper Transcription Factors 20 ZNF644 30834109 Cell Biosci 2019 PMC6385473 10.1186/s13578-019-0280-4 0 4 0 140 Humans|Mice|Animals|*Point Mutation|*Myopia|Eye|Transcription Factor|*Missense Mutation|Mutation|Zinc Finger|Disease Models, Animal|Gene Expression Regulation|ZNF644 protein, human 20 ZNF804A 31727397 J Affect Disord 2019 10.1016/j.jad.2019.11.009 0 0 0 45 Humans|Adolescent|*Bipolar Disorder|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Risk Factors|Case-Control Studies 172 ZNF804A 31464994 Psychiatr. Genet. 2019 10.1097/YPG.0000000000000231 0 0 0 45 Depressive Disorder, Major|Bipolar Disorder|Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Gene Frequency|*Psychotropic Drugs|Kruppel-Like Transcription Factors|Genotype|Zinc Fingers 172 ZNF804A 31336035 FEBS Open Bio 2019 PMC6768289 10.1002/2211-5463.12704 0 0 0 45 Male|Humans|*Schizophrenia|IL2RA protein, human|Interleukin-2 Receptor alpha Subunit|ELISA|Autoantibodies|Antipsychotics|*Chinese|Immunoglobulin G|Antigens|Biomarkers, Tumor|Receiver Operating Characteristic|Case-Control Studies|*Plasma|anti-IgG|ZNF804A protein, human|Kruppel-Like Transcription Factors 172 ZNF804A 31294817 Nicotine Tob. Res. 2019 PMC7249921 10.1093/ntr/ntz099 1 3 0 45 Dependence, Nicotine|Smoking|Cigarette|*Phenotypes|Surveys and Questionnaires 172 ZNF804A 31193559 Data Brief 2019 PMC6536608 10.1016/j.dib.2019.103985 0 0 0 45 Russia|*Schizophrenia|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genotype|Kruppel-Like Transcription Factors 172 ZNF804A 31190057 Am. J. Clin. Nutr. 2019 PMC6669061 10.1093/ajcn/nqz076 3 0 0 45 *Genome-Wide Association Study|*Breakfast|Genetic Predisposition to Disease|Times, Meal|Polymorphism, Single Nucleotide|Phenotype|Cohort Studies 172 ZNF804A 31122238 BMC Psychiatry 2019 PMC6533675 10.1186/s12888-019-2144-1 0 0 0 45 Humans|*Autistic Disorder|*Asian Continental Ancestry Group|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genetic Association Studies|Schizophrenia|Genotype|Kruppel-Like Transcription Factors|*Family Relations|ZNF804A protein, human 172 ZNF804A 31076262 Schizophr. Res. 2019 10.1016/j.schres.2019.04.018 0 1 0 45 Male|Female|Humans|*Schizotypal Personality Disorder|*Healthy Volunteers|Cohort Studies|*Schizophrenia|Psychosis|*Attention|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Functions, Cognitive|Phenotype|Alleles|Kruppel-Like Transcription Factors|Personality|CACNA1C protein, human|Calcium Channels, L-Type|ZNF804A protein, human 172 ZNF804A 31049583 Cardiovasc. Res. 2019 PMC6918066 10.1093/cvr/cvz106 3 0 0 45 Humans|*Genome-Wide Association Study|Genotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|*Chromosome 1|Quantitative Trait Loci|Alleles|European Continental Ancestry Group|*Syncope|*Shock 172 ZNF804A 30962687 Neuropsychiatr Dis Treat 2019 PMC6432899 10.2147/NDT.S174728 1 0 0 45 *Brain|*Imaging, Magnetic Resonance|Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Kruppel-Like Transcription Factors|Case-Control Studies 172 ZNF804A 30852803 Neurosci Bull 2019 PMC6616604 10.1007/s12264-019-00357-w 1 1 0 45 Humans|Schizophrenia|Dorsolateral Prefrontal Cortex|Genotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Kruppel-Like Transcription Factors|Chinese|ZNF804A protein, human|COMT protein, human|Catechol O-Methyltransferase 172 ZNF804A 30760334 Clin Epigenetics 2019 PMC6375219 10.1186/s13148-019-0614-4 2 0 0 45 Humans|*Cross-Sectional Studies|United Kingdom|*Epigenetic|CpG Islands|Epigenesis, Genetic|DNA Methylation|Twins, Monozygotic|Genome-Wide Association Study|*Periodontitis 172 ZNF804A 30670685 Transl Psychiatry 2019 PMC6342935 10.1038/s41398-019-0369-x 2 0 0 45 Humans|*Autism Spectrum Disorder|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Alleles|Gene Frequency|Genotype|*Promoter Regions, Genetic|Case-Control Studies|Kruppel-Like Transcription Factors|Transcription Factor|Phenotypes|HSF2 protein, human|Heat-Shock Proteins|ZNF804A protein, human 172 ZNF804A 30626913 Mol. Psychiatry 2019 PMC7303007 10.1038/s41380-018-0336-6 4 0 0 45 *Bipolar Disorder|*Genome-Wide Association Study|*Depressive Disorder, Major|*Depression|*Schizophrenia|*Genetic Loci|*Phenotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Recurrence 172 ZNF91 30887516 J Surg Oncol 2019 10.1002/jso.25446 4 0 0 55 *Urinary Bladder Neoplasms|*Prognosis|Neoplasm Recurrence, Local|Kaplan-Meier Estimate|Biomarkers, Tumor|Area Under Curve|ROC Curve|Proportional Hazards Models|Gene Expression Profiling|Predictive Value of Tests 26 ZNF91 30598658 Clin Proteomics 2019 PMC6302491 10.1186/s12014-018-9215-z 5 0 0 55 Humans|Female|Liquid Chromatography|*Carcinoma, Ovarian Epithelial|*Peptides|Spectrometry, Mass, Electrospray Ionization|Tandem Mass Spectrometry|Proteomics|Proteins|*Ovarian Cancer|*Plasma|Algorithms 26 ZPBP2 31560728 PLoS ONE 2019 PMC6764692 10.1371/journal.pone.0223212 0 1 0 22 Humans|Mice|Animals|Genome-Wide Association Study|*Circadian Clocks|Alleles|Genetic Predisposition to Disease|Asthma|Polymorphism, Single Nucleotide|Membrane Proteins|DNA Methylation|Promoter Regions, Genetic|Neoplasm Proteins|Genotype|Egg Proteins|Phenotype|Gene Expression|Regulatory Sequences, Nucleic Acid|Lungs|ORMDL3 protein, human|ZPBP2 protein, human 39 1.2.7.1 30512611 Rev Prat 2018 0 0 0 0 Humans|*Gambling|Behavior, Addictive|Diagnostic and Statistical Manual of Mental Disorders|Substance-Related Disorders|Comorbidity|Prevalence 429 1.2.7.1 30452102 Environ. Microbiol. 2018 10.1111/1462-2920.14477 0 0 0 0 *Bacteria|*Genomics|*Phylogeography|RNA, Ribosomal, 16S|Phylogeny|DNA, Bacterial|Sequence Analysis, DNA|Bacterial Proteins 429 1.2.7.1 30373630 Parasit Vectors 2018 PMC6205798 10.1186/s13071-018-3141-9 2 0 0 0 Child|Humans|*Blastocystis|*Ferredoxins|Blastocystis Infections|RNA, Ribosomal, 18S|*Ferredoxin Oxidoreductase, Pyruvate|Genetic Variation|DNA, Protozoan|Phylogeny|DNA, Ribosomal|Polymorphism, Genetic|Sequence Analysis, DNA|Feces|Pyruvates 429 1.2.7.1 30512611 Rev Prat 2018 0 0 0 0 Humans|*Gambling|Behavior, Addictive|Diagnostic and Statistical Manual of Mental Disorders|Substance-Related Disorders|Comorbidity|Prevalence 429 1.2.7.1 30452102 Environ. Microbiol. 2018 10.1111/1462-2920.14477 0 0 0 0 *Bacteria|*Genomics|*Phylogeography|RNA, Ribosomal, 16S|Phylogeny|DNA, Bacterial|Sequence Analysis, DNA|Bacterial Proteins 429 1.2.7.1 30373630 Parasit Vectors 2018 PMC6205798 10.1186/s13071-018-3141-9 2 0 0 0 Child|Humans|*Blastocystis|*Ferredoxins|Blastocystis Infections|RNA, Ribosomal, 18S|*Ferredoxin Oxidoreductase, Pyruvate|Genetic Variation|DNA, Protozoan|Phylogeny|DNA, Ribosomal|Polymorphism, Genetic|Sequence Analysis, DNA|Feces|Pyruvates 429 A2ML1 30103046 Autoimmun Rev 2018 10.1016/j.autrev.2018.04.008 6 0 0 58 *Pemphigus|*Paraneoplastic Syndrome|Desmoglein 3|Desmoglein 1|Autoantibodies|Autoantigens|Autoimmunity|Epitopes|*Phenotype 39 A2ML1 30078240 Zhonghua Er Ke Za Zhi 2018 10.3760/cma.j.issn.0578-1310.2018.08.007 0 0 0 58 39 A2ML1 29949068 J Community Genet 2018 PMC6325045 10.1007/s12687-018-0368-2 0 0 0 58 *Genetic Counseling|*Prevalence|*Otitis Media|alpha-Macroglobulins|Genetic Susceptibility|Genotypes 39 A2ML1 29749538 Oncol. Rep. 2018 PMC6059744 10.3892/or.2018.6426 11 3 0 58 Humans|*Prognosis|*Carcinoma, Squamous Cell|CpG Islands|DNA Methylation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Epigenesis, Genetic|Lung Cancer|Promoter Regions, Genetic|*Carcinoma, Non-Small-Cell Lung|Gene Expression Profiling|mRNA|Cobl protein, human|Microfilament Proteins 39 A2ML1 29402968 Sci Rep 2018 PMC5799236 10.1038/s41598-018-20894-0 1 4 0 58 Humans|Costello Syndrome|Noonan Syndrome|Failure to Thrive|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Ectodermal Dysplasia|LEOPARD Syndrome|Facies|ras Proteins|Proto-Oncogene Proteins B-raf|Heart Defects, Congenital|*Sequencing, Next-Generation|Mutations|Phenotype|Mutations, Germline|MAP Kinase Signaling System|Signal Transduction|RIT1 protein, human 39 A4GALT 30592300 Transfusion 2018 PMC6402986 10.1111/trf.15089 3 0 0 57 44 A4GALT 29709005 PLoS ONE 2018 PMC5927444 10.1371/journal.pone.0196627 0 0 0 57 44 A4GALT 29572228 Cancer Res. 2018 10.1158/0008-5472.CAN-17-2223 3 0 0 57 44 A4GALT 29553830 FASEB J. 2018 PMC6071062 10.1096/fj.201701374R 3 2 0 57 44 A4GALT 29438961 Blood 2018 10.1182/blood-2017-08-803080 3 0 0 57 44 A4GALT 29399809 Transfusion 2018 10.1111/trf.14515 2 1 0 57 44 ABCF2 30524410 Front Microbiol 2018 PMC6262023 10.3389/fmicb.2018.02831 2 1 0 143 Escherichia coli Proteins|Escherichia coli|Escherichia coli Infections|Tight Junctions|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Epithelial Cells|Cell Line 33 ABCF2 30419281 Life Sci. 2018 10.1016/j.lfs.2018.11.018 0 0 0 143 Humans|*Proteomics|*Open Reading Frames|*Colorectal Cancer|Proteome|*Peptides|*Colonic Neoplasms|Neoplasm Proteins|Biomarkers, Tumor|Mutations|*Cyclin-Dependent Kinase Inhibitor p16|RBM10 protein, human|RNA-Binding Proteins 33 ABCF2 29421658 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.02.033 3 4 0 143 Humans|*Oxaliplatin|*Stomach Neoplasms|polyene phosphatidylcholine|*Phosphatidylcholines|Organoplatinum Compounds|Antineoplastic Agents|Drug Resistance, Neoplasm|Cell Line, Tumor|Apoptosis|Cell Cycle|Cell Proliferation 33 ABCF2 29402780 Cell. Physiol. Biochem. 2018 PMC7202864 10.1159/000487100 9 1 0 143 Infant, Newborn|Humans|Female|Pregnancy|*ATP-Binding Cassette Transporters|*Chorioamnionitis|*Placenta|ATP Binding Cassette Transporter, Subfamily G, Member 2|ATP Binding Cassette Transporter, Subfamily B|ATP Binding Cassette Transporter, Subfamily B, Member 1|Drug Resistance, Multiple|Trophoblasts|Neoplasm Proteins|MicroRNAs|MIRN331 microRNA, human 33 ABCF2 29371766 Indian J Clin Biochem 2018 PMC5766467 10.1007/s12291-017-0651-8 5 2 0 143 *Carcinoma, Hepatocellular|*Liver Neoplasms|MicroRNAs|Doxorubicin|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B|multidrug resistance-associated protein 1|Multidrug Resistance-Associated Proteins|HepG2 Cells|Drug Resistance, Multiple|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|Antineoplastic Agents|Cell Cycle|Downregulation|Cell Line, Tumor|Cell Proliferation|Apoptosis 33 ABHD11 30575903 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201812_16627 5 5 0 25 Humans|*RNA, Long Noncoding|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Prognosis|*Pancreatic Cancer|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Signal Transduction|Apoptosis|RNA, Small Interfering|*Promoter Regions, Genetic|Biomarkers, Tumor|Disease Progression 32 ABHD11 30537177 J. Cell. Physiol. 2018 10.1002/jcp.27877 1 6 0 25 Humans|*RNA, Long Noncoding|*Cell Proliferation|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Carcinogenesis|Wnt11 protein, human|*Wnt Proteins|Cell Line, Tumor|Up-Regulation|Apoptosis|*Colonic Neoplasms|*Neoplastic Processes|Disease Progression|MIRN1254 microRNA, human 32 ABHD11 30429229 Biosci. Rep. 2018 PMC6294614 10.1042/BSR20181386 2 4 0 25 Humans|*RNA, Long Noncoding|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|Cell Movement|*Colonic Neoplasms|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Apoptosis|Up-Regulation|Disease Progression|Kaplan-Meier Analysis|SOX4 protein, human|SOXC Transcription Factors 32 ABHD11 30197680 Oncol Lett 2018 PMC6126347 10.3892/ol.2018.9199 8 0 0 25 Humans|*lncRNA|*Stomach Neoplasms|Receiver Operating Characteristic|Biomarkers, Tumor|Area Under Curve|Gene Expression Regulation, Neoplastic|Gastritis 32 ABHD11 30078471 Pathol. Res. Pract. 2018 10.1016/j.prp.2018.07.023 8 0 0 25 Humans|AA174084 non-coding RNA, human|*Long Non-Coding RNA|*Stomach Neoplasms|Reproducibility of Results|*Gastric Juice|Tumor Markers|Prognosis|Gene Expression Regulation, Neoplastic|Specificity|Early Detection of Cancer|ROC Curve 32 ABHD11 29799152 J. Cell. Mol. Med. 2018 PMC6050509 10.1111/jcmm.13675 9 22 0 25 Humans|Female|Mice|Animals|*RNA, Long Noncoding|CCND1 protein, human|*Cyclin D1|Mice, Nude|*Endometrial Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Up-Regulation|Cell Line, Tumor|Cell Movement|CDK2 protein, human|Cyclin-Dependent Kinase 2|Biomarkers, Tumor|Downregulation|Disease Progression 32 abhd2 30184496 Cell Rep 2018 PMC6177234 10.1016/j.celrep.2018.08.016 6 1 0 142 Male|Female|Humans|*Rotation|*Sperm|Sperm Motility|Calcium Channel|Sperm Capacitation|Fertility|Ion Transport|Cell Membrane|Proton|ABHD2 protein, human|Hydrolases 30 abhd2 30045016 Cell. Physiol. Biochem. 2018 10.1159/000491982 10 0 0 142 *Hyperlipidemias|Gene Ontology|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Profiling|Computational Biology|Databases, Genetic 30 ABI3BP 30145303 Psychiatry Res 2018 PMC6207450 10.1016/j.psychres.2018.07.017 5 0 0 65 Humans|*Suicidal Ideation|*Suicide, Attempted|*Veterans|*Genome-Wide Association Study|*Military Personnel|Self-Injurious Behavior|Risk Factors 27 ABI3BP 30111857 Sci Rep 2018 PMC6093887 10.1038/s41598-018-29789-6 6 3 0 65 Humans|Quality of Life|Genome-Wide Association Study|*Quadriceps Muscle|*Chronic Obstructive Pulmonary Disease|*Mitochondria|Muscle, Skeletal|Lung|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|*Extracellular Matrix|POSTN protein, human|Cell Adhesion Molecules|PANX1 protein, human|Nerve Tissue Proteins|Connexins 27 ACAP2 30212824 Cell. Physiol. Biochem. 2018 10.1159/000493457 27 5 0 127 Humans|*circRNA|*T-Lymphoma Invasion and Metastasis-inducing Protein 1|RNA, Micro|Gene Expression Regulation, Neoplastic|*Colon Cancer|Cell Movement|Cell Proliferation|Cell Line, Tumor|RNA, Small Interfering|3' Untranslated Regions|*Colon|Disease Progression|TIAM1 protein, human|MIRN21 microRNA, human 26 ACAP2 29410707 Mol Cytogenet 2018 PMC5781338 10.1186/s13039-018-0358-4 0 3 0 127 Humans|*Arnold-Chiari Malformation|Sprengel deformity|*Scapula|*Shoulder Joint|Myelomeningocele|Chromosomes 26 ACOD1 30293776 Cell Metab. 2018 10.1016/j.cmet.2018.09.003 23 0 0 3025 Humans|itaconic acid|*Immune Tolerance|*Succinates|Monocytes|Macrophages|Innate Immune Response|Lipopolysaccharides|SDHD protein, human|Succinate Dehydrogenase|Sepsis|Endotoxemia|Glycolysis|*Immune System Diseases|IRG1 protein, human 24 ACOD1 29949160 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201806_15268 3 1 0 3025 Animals|Mice|Humans|*Epithelial-Mesenchymal Transition|*Glioma|*Cell Migration|MicroRNAs|Brain Neoplasms|Antagomirs|RNA Interference|Cell Proliferation|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|Cell Line, Tumor|3' Untranslated Regions|Mice, Nude|Down-Regulation|*Neoplastic Processes|Prognosis|IRG1 protein, human|MIRN378 microRNA, human 24 ACOD1 29920191 J. 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Chem. 2018 PMC6005419 10.1074/jbc.RA118.002851 6 2 0 15 Male|Mice|Animals|*Protamines|*Methyltransferase, Histone|*Acrosin|*Spermiogenesis|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Spermatids|Histone H3|ACRBP protein, human|*Carrier Proteins|Testis|Epigenesis, Genetic|DNA Methylation|Lysine 39 ADAM29 30429210 Mol. Cell Proteomics 2018 PMC6356071 10.1074/mcp.RA118.001170 2 2 0 13 Male|Humans|Mice|Animals|*Proteomics|*Spermatozoa|Infertility, Male|Sperm-Oocyte Interaction|*Proteins|*Homozygote|Testis|*Mutation, Missense 31 ADAM29 30414097 J. Neurooncol. 2018 10.1007/s11060-018-03029-3 6 1 0 13 Humans|*Glioblastoma|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Prognosis|Biomarkers, Tumor|Cell Proliferation|RNA, Messenger|Neural Stem Cell|Mutation 31 ADAM29 30008827 Oncol Lett 2018 PMC6036465 10.3892/ol.2018.8838 0 11 0 13 Humans|*Stomach Neoplasms|Neoplasm Invasiveness|Prognosis|*Stomach|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Adenocarcinoma|Biomarkers, Tumor|Lymphatic Metastasis|Cell Line, Tumor|Integral Membrane Protein|RNA, Messenger|Real-Time Polymerase Chain Reaction|ADAM29 protein, human|ADAM Proteins 31 ADAMDEC1 30373853 J. Immunol. 2018 10.4049/jimmunol.1701487 2 0 0 24 Mice|Animals|FCGR2B protein, human|*Receptors, IgG|*B Cells|Mice, Inbred C57BL|*Myeloid Cells|*Lymphocyte Activation|Lupus Nephritis|Disease Models, Animal 42 ADAMDEC1 30352365 Mol. Immunol. 2018 PMC6260809 10.1016/j.molimm.2018.09.019 3 1 0 24 Humans|*RNA|EP300 protein, human|*E1A-Associated p300 Protein|NF-kappa B|ADAM Proteins|Promoter Regions, Genetic|Up-Regulation|Mitogen-Activated Protein Kinases|*Regulatory Sequences, Nucleic Acid|ADAM28 protein, human 42 ADAMDEC1 30260019 J. Cell. Biochem. 2018 10.1002/jcb.27741 2 1 0 24 Humans|*Synovial Membrane|*Rheumatoid Arthritis|*Osteoarthritis|Gene Ontology|Gene Expression Profiles|Gene Regulatory Networks|Gene Expression Profiling|Databases, Genetic|Oligonucleotide Array Sequence Analysis|Protein Interaction Maps|Computational Biology|Signal Transduction 42 ADAMDEC1 30135119 J. Virol. 2018 PMC6189496 10.1128/JVI.01362-18 2 4 0 24 EBNA-3C, epstein-barr virus|*Epstein-Barr Virus Nuclear Antigens|Epstein Barr Virus|lymphocryptovirus nuclear antigen 3C|*Antigens, Viral|*Viral Proteins|RBPJ protein, human|Immunoglobulin J Recombination Signal Sequence-Binding Protein|Epstein-Barr Virus Infections|B Cells|Chromatin Immunoprecipitation|Cell Line 42 ADAMDEC1 30131040 Kardiologiia 2018 1 0 0 24 *Coronary Artery Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Myocardial Infarction|Genotype 42 ADAMDEC1 29941981 Sci Rep 2018 PMC6018119 10.1038/s41598-018-27469-z 2 8 0 24 Dogs|Animals|decysin|ADAM Proteins|Cell Transformation, Neoplastic|Filamin|Signal Transduction|Madin Darby Canine Kidney Cells|Epithelium|Cancer 42 ADAMDEC1 29936897 Acta Otolaryngol. 2018 10.1080/00016489.2018.1481296 1 0 0 24 *Nasal Polyps|decysin|*Sinusitis|Rhinitis|Nasal Mucosa|Eosinophils|*Chronic Disease|RNA, Messenger|Real-Time Polymerase Chain Reaction 42 ADARB2 30197321 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 10.11817/j.issn.1672-7347.2018.08.014 0 0 0 83 34 ADARB2 29967262 Cancer Res. 2018 10.1158/0008-5472.CAN-18-0532 43 1 0 83 34 ADARB2 29848620 G3 (Bethesda) 2018 PMC6027867 10.1534/g3.118.200401 0 2 0 83 34 ADARB2 29719497 Front Neurosci 2018 PMC5914295 10.3389/fnins.2018.00243 8 6 0 83 34 ADGRG6 30549416 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40531 0 0 0 122 Child|Humans|*Intellectual Disability|Cerebellar Hypoplasia|Nervous System Malformations|Microcephaly|Developmental Disabilities|Sequencing, Whole Exome|Cerebellum|Exome|Pedigree|Phenotype|Homozygote|Mutation 42 ADGRG6 30401719 Mol. Cancer Res. 2018 10.1158/1541-7786.MCR-18-0363 2 0 0 122 *Introns|*Prevalence|Urinary Bladder Neoplasms|Bladder|Mutations|Neoplasm Recurrence, Local|Neoplasm Invasiveness|Biomarkers, Tumor|Kaplan-Meier Estimate|Signal Transduction 42 ADGRG6 30234802 Spine 2018 10.1097/BRS.0000000000002866 0 0 0 122 Humans|Adolescent|*Scoliosis|*Genome-Wide Association Study|*Chinese|Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Homeodomain Proteins|Genotype|*Disease Progression|*Kyphosis|Case-Control Studies|Transcription Factors 42 ADGRG6 30069010 Sci Rep 2018 PMC6070519 10.1038/s41598-018-29011-7 2 1 0 122 Humans|Adolescent|Genome-Wide Association Study|*Scoliosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|*Ethnic Groups|Linkage Disequilibrium|Asian Continental Ancestry Group|*Kyphosis|Genotype|Receptors, G-Protein-Coupled|East Asia|Northern Europe 42 AEBP1 30548383 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.60679 3 1 0 112 Male|Humans|Female|*Siblings|*Connective Tissue Diseases|Ehlers-Danlos Syndrome|Homozygote|Heterozygote|Pedigree|Phenotype|Connective Tissue|Alleles|Whole Exome Sequencing|Mutation|High-Throughput Nucleotide Sequencing|Codon, Nonsense|AEBP1 protein, human|Carboxypeptidases|Repressor Proteins 91 AEBP1 30369943 Front Genet 2018 PMC6194152 10.3389/fgene.2018.00453 4 0 0 112 Humans|Female|*Endometriosis|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Genes, Homeobox|Transcription Factors|IER3 protein, human|Membrane Proteins|Apoptosis Regulatory Proteins|CC2D2A protein, human|Proteins 91 AFAP1L2 30521666 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-23962 3 0 0 160 Animals|*Transcriptome|Zebrafish Proteins|Zebrafish|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Optic Disk|Coloboma|Morphogenesis|PAX2 Transcription Factor|In Situ Hybridization|Retinal Ganglion Cell|*Microarray Analysis 30 AFAP1L2 29323101 Med. Sci. Monit. 2018 PMC5772338 10.12659/msm.905900 0 19 0 160 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Microfilament Proteins|Short Hairpin RNA|Cell Proliferation|Apoptosis|RNA Interference|Cell Cycle|CASP3 protein, human|Caspase 3|A549 Cells|Cell Line, Tumor|Adaptor Proteins, Signal Transducing|Cell Movement|Signal Transduction|Transfection|Downregulation|Actin Cytoskeleton 30 AFF2 30555518 Front Genet 2018 PMC6284054 10.3389/fgene.2018.00594 3 0 0 75 Child|Humans|*Whole Exome Sequencing|*Autism Spectrum Disorder|Exome|DNA Copy Number Variations|Genetic Predisposition to Disease|Mutation|Sequence Analysis|Intellectual Disability|Neurodevelopmental Disorders|Chinese|Cohort Studies 108 AFF2 30417949 J. Anim. Breed. Genet. 2018 10.1111/jbg.12365 3 0 0 75 Animals|Humans|Swine|China|*Phenotype|Studies, Genome-Wide Association|Quantitative Trait Loci|Genotype|Polymorphism, Single Nucleotide|Breeding|*Chinese 108 AFF2 30392976 Stem Cell Reports 2018 PMC6235011 10.1016/j.stemcr.2018.10.003 16 1 0 75 Humans|*Autistic Disorder|Autism Spectrum Disorder|*Gene Editing|*Neurons|Induced Pluripotent Stem Cells|Postsynaptic Current, Excitatory|Cell Differentiation|Cells, Cultured|Phenotypes|Electrophysiological Phenomena|Sequencing, RNA 108 AFF2 30264515 Mol Genet Genomic Med 2018 PMC6305680 10.1002/mgg3.425 1 0 0 75 Male|Humans|Female|Young Adult|Adult|*Intellectual Disability|*Hemophilia B|Fragile X Syndrome|Fragile X Mental Retardation Protein|Factor IX|Chromosome Deletion|Chromosomes, Human, X|Phenotype|Heterozygote|Chromosome Mapping|*Chromosome Structures|Mutations|FMR1 protein, human 108 AGAP1 30472483 Eur J Med Genet 2018 10.1016/j.ejmg.2018.11.020 1 0 0 202 Male|Humans|*Autistic Disorder|*Intellectual Disability|Comparative Genomic Hybridization|Chromosome Deletion|Phenotype|*Chromosome Structures|Syndromes|AGAP1 protein, human|GTPase-Activating Proteins|SH3BP4 protein, human|Adaptor Proteins, Signal Transducing 25 AJAP1 30234802 Spine 2018 10.1097/BRS.0000000000002866 0 0 0 135 Humans|Adolescent|*Scoliosis|*Genome-Wide Association Study|*Chinese|Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Homeodomain Proteins|Genotype|*Disease Progression|*Kyphosis|Case-Control Studies|Transcription Factors 58 AKAP4 30545223 Klin Onkol 2018 10.14735/amko2018429 0 0 0 1712 Humans|Male|*Lactobacillus crispatus|*HeLa Cells|*Down-Regulation|*Lactobacillus rhamnosus|*Genes, Regulator|Lactobacillus|Prognosis|TSGA10 protein, human|Proteins|AURKC protein, human|Aurora Kinase C 93 AKAP4 30415212 J. Med. Genet. 2018 10.1136/jmedgenet-2018-105486 6 0 0 1712 Humans|Male|Sperm Motility|*Homozygote|Infertility, Male|Sperm Tail|Spermatozoa|Spermatozoa, Abnormal|Flagella|Whole Exome Sequencing|Cytoskeletal Proteins|Mutation 93 AKAP4 30145836 J. Cell. 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Genet. 2018 PMC5985266 10.1016/j.ajhg.2018.01.015 24 0 0 222 Humans|*Blood Pressure|*Genome-Wide Association Study|SNPs|Systole|Asian|*Blood Pressure Determination|Genetic Loci|European Continental Ancestry Group|*Smoking Behavior|Diastole 46 AKTIP 29321599 Sci Rep 2018 PMC5762880 10.1038/s41598-017-18767-z 0 0 0 222 Humans|*Quantitative Trait Loci|Genome-Wide Association Study|*Adiposity|*Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|SNPs|*Phenotype|*RNA Splicing|Adipose Tissue|Genotype|Exon|UBE2E1 protein, human|Ubiquitin-Conjugating Enzymes|FTO protein, human 46 ALPK1 30455202 EMBO Rep. 2018 PMC6280651 10.15252/embr.201846943 4 1 0 500 *Pathogen-Associated Molecular Pattern Molecules|*Heptoses|Immunity, Innate|NF-kappa B|Signal Transduction|Adaptor Proteins, Signal Transducing|Bacteria|Adenosine Diphosphate 47 ALPK1 30337625 Sci Rep 2018 PMC6193983 10.1038/s41598-018-33500-0 0 1 0 500 Cricetinae|Animals|Humans|*Introns|HEK293 Cells|*Regulatory Sequences, Nucleic Acid|CHO Cells|Transfection|*Recombinant Proteins|Cricetulus|Plasmids|Promoter Regions, Genetic|Genetic Vectors|Green Fluorescent Proteins|Gene Expression|Recombinant Fusion Proteins|Peptide Elongation Factor 1|Simian virus 40|Cytomegalovirus|Poly A 47 ALPK1 30315765 Am. 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Cell 2018 PMC6292839 10.1016/j.molcel.2018.09.010 4 1 0 183 Animals|H2AX protein, human|*Histones|High Mobility Group Proteins|Nucleosomes|Transcriptional Elongation Factors|Histone Chaperones|Chromatin|*DNA Damage|DNA-Binding Proteins|Transcription Factors|Saccharomyces cerevisiae Proteins|Cell Cycle Proteins|Protein Binding 36 ANP32E 30329026 J Crohns Colitis 2018 10.1093/ecco-jcc/jjy171 1 1 0 183 Humans|*Colitis, Ulcerative|*Systems Biology|Colon|*Steroids|Intestinal Mucosa|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|MicroRNAs|RNA, Messenger|Glucocorticoids|Transcriptomes 36 ANP32E 29633513 Mol Oncol 2018 PMC5983205 10.1002/1878-0261.12202 4 23 0 183 Humans|Mice|Animals|*Triple-Negative Breast Cancer|Neoplasm Recurrence, Local|*Upregulation|*Tumorigenesis|*Transcriptional Activation|Cell Proliferation|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Prognosis|Cell Line, Tumor|Mice, Nude|Cell Movement|progesterone receptor B|Progesterone Receptor|Xenograft Model Antitumor Assays|Receptors, Estrogen|E2F1 protein, human|E2F1 Transcription Factor 36 ANP32E 29524612 Biochim Biophys Acta Gene Regul Mech 2018 PMC6053077 10.1016/j.bbagrm.2018.03.002 3 16 0 183 Animals|*Protein Phosphatase 2|*Histones|Nucleosomes|Transcription Start Sites|Saccharomyces cerevisiae|Nuclear Proteins|*Gene Expression Regulation|Promoter Regions, Genetic|Phosphoproteins|Cell Nucleus 36 ANXA10 30553612 Eur. 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Anim. 2018 10.1111/rda.13280 0 6 0 85 Pregnancy|Mice|Female|Swine|Animals|*Annexin A8|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Signal Transduction|*Endometrium|Phosphatidylinositol 3-Kinases|Phosphorylation|Cell Proliferation|Cell Movement|Mitogen-Activated Protein Kinases|Estrous Cycle|Epidermal Growth Factor|Epithelial Cells|Sus scrofa|mRNA|Cell Line|Genes, cdc 33 AOAH 30021797 J. Exp. Med. 2018 PMC6122967 10.1084/jem.20172225 0 42 0 51 Mice|Animals|lipopolysaccharide B|*Lipopolysaccharides|*Lipase|*Lung|*Asthma|Mite, Housedust|*Epithelial Cell|Th2 Cells|acyloxyacyl hydrolase|Carboxylic Ester Hydrolases|Eosinophils|Dendritic Cells|Mice, Knockout|Cytokines 51 AOAH 29343645 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC5798384 10.1073/pnas.1719834115 2 0 0 51 Animals|*Lipopolysaccharides|acyloxyacyl hydrolase|Carboxylic Ester Hydrolases|Lipid A|Endotoxins|*Mammals|Acids, Fatty|Active Site 51 AP3M2 30371777 Hum. Mol. Genet. 2018 PMC6381320 10.1093/hmg/ddy376 4 9 0 40 Humans|*Astrocytes|*Proteostasis|Induced Pluripotent Stem Cells|*Neurons|Alzheimer Disease|Amyloid beta-Peptides|tau Proteins|Amyloid beta-Protein Precursor|Phosphorylation|*Module, Gene|Cells, Cultured|SCARB2 protein, human|Receptors, Scavenger|Lysosome-Associated Membrane Glycoproteins 25 ARL4C 30594917 Cancer Biomark 2018 10.3233/CBM-181836 4 0 0 179 Humans|Female|*Endometriosis|*ADP-Ribosylation Factor|Neoplasm Recurrence, Local|*Ovarian Cancers|Adenocarcinoma, Clear Cell|Carcinoma, Endometrioid|Carcinoma, Ovarian Epithelial|Prognosis|Biomarkers, Tumor|Neoplasm Staging|Ovary|Disease Progression|Case-Control Studies|ARL4C protein, human 38 ARL4C 30357833 J. Pathol. 2018 10.1002/path.5189 6 4 0 179 Humans|*Glioblastoma|*Proto-Oncogene Proteins c-akt|MTOR protein, human|*TOR Serine-Threonine Kinases|PTEN protein, human|*PTEN Phosphohydrolase|Phosphatidylinositol 3-Kinases|Signal Transduction|Brain Neoplasms|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Xenograft Model Antitumor Assays|Ubiquitination|*Neoplastic Processes|Great Britain|Ireland 38 ARL4C 30203055 Biol. Reprod. 2018 PMC6378860 10.1093/biolre/ioy199 6 0 0 179 Pregnancy|Male|Cattle|Animals|Female|trophoblastin|*Transcriptome|Pregnancy Proteins|Interferon Type I|*Endometrium|Pregnancy, Animal|Uterus|Estrous Cycle|*Embryo, Mammalian|RNA, Messenger|MLPH protein, human|Adaptor Proteins, Signal Transducing 38 ARL4C 30108155 J. Lipid Res. 2018 PMC6168314 10.1194/jlr.P080218 4 0 0 179 Humans|*Genome-Wide Association Study|*Arabs|*Hypertriglyceridemia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Recessive Gene|Phenotype|European Continental Ancestry Group|Lipids|Kuwait 38 ARL4C 29860346 Int J Epidemiol 2018 PMC6124615 10.1093/ije/dyy091 19 2 0 179 Humans|Adult|Male|Female|Middle Aged|Pregnancy|*DNA Methylation|*Smoke|*B-DNA|Maternal Exposure|CpG Islands|Prenatal Exposure Delayed Effects|Epigenesis, Genetic|Cohort Studies|Smoking|Genome-Wide Association Study|Fetal Blood|*Biomarkers|*Tobacco|*Protein Processing, Post-Translational 38 ARL4C 29522754 Exp. Cell Res. 2018 PMC6652231 10.1016/j.yexcr.2018.03.001 1 3 0 179 *Plasma Membrane|*Biological Transport|Cholesterol|Niemann-Pick Diseases|Fibroblasts|Lipid Metabolism|Cells, Cultured 38 ARL4C 29432742 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.02.066 1 5 0 179 Humans|*Osteogenesis|*Wnt Signaling Pathway|*Cell Differentiation|*Adipocytes|Mesenchymal Stem Cells|Stem Cells|Tissue Engineering|Cells, Cultured|ARL4C protein, human|ADP-Ribosylation Factors 38 ARVCF 30479852 Dermatol Pract Concept 2018 PMC6246068 10.5826/dpc.0804a02 0 0 0 78 Humans|Pemphigus and fogo selvagem|*Pemphigus|Autoantibodies|Skin|Desmoplakins|Endemic Diseases 79 ARVCF 29872493 Oncotarget 2018 PMC5973874 10.18632/oncotarget.24821 1 11 0 78 Pregnancy|Humans|Female|*Endometrium|Embryo Implantation|*Recurrent Miscarriages|*Androgens|Cell Line, Tumor 79 ARVCF 29768670 Clin. Exp. Dermatol. 2018 10.1111/ced.13566 1 0 0 78 Humans|Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|*Desmoplakins|Skin|Endemic Diseases|*Kidney|Immunohistochemistry|Colombia|ARVCF protein, human|Phosphoproteins|Cell Adhesion Molecules|Armadillo Domain Proteins 79 ARVCF 29445566 Dermatol Pract Concept 2018 PMC5808363 10.5826/dpc.0801a01 1 2 0 78 Humans|Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|Colombia|*Cell Junctions|Desmoplakins|South America|Skin|Endemic Diseases|Immunohistochemistry|*Central Nervous System|Optic Nerve 79 ASTL 30535617 Genes Genomics 2018 10.1007/s13258-018-0774-1 0 0 0 52 Animals|*Hepatopancreas|*Brachyura|*Cadmium|*Transcriptome|Gene Expression Profiling|*Heavy Metal Poisoning|Wetland|Water Pollutants, Chemical 96 ASTL 30276575 Neurosurg Rev 2018 10.1007/s10143-018-1034-1 0 0 0 52 Humans|*Pituitary Neoplasms|Quality of Life|*Adenoma|Anosmia|Pituitary Gland|Sphenoid Bone|Neuroendoscopy|Olfaction|Microsurgery|Surgical Flaps|Prospective Studies|Treatment Outcome|Postoperative Complications 96 ASTL 29507667 Oncotarget 2018 PMC5823626 10.18632/oncotarget.23944 0 11 0 52 *Pancreatic Cancer|*Radioimmunotherapy|Antigens, Neoplasm|Antibodies, Monoclonal|Pancreas|Cell Line, Tumor|Xenograft Model Antitumor Assays|Blotting, Western|Immunoconjugates 96 ASTL 29358633 Sci Rep 2018 PMC5778054 10.1038/s41598-018-19497-6 19 5 0 52 Male|Mice|Animals|*Sperm|Oocytes|Phosphoinositide Phospholipase C|Sperm Injections, Intracytoplasmic|Fertilization|Fertilization in Vitro|Calcium Signaling 96 ASTN1 30509219 BMC Cancer 2018 PMC6276155 10.1186/s12885-018-5125-8 8 0 0 24 Humans|Female|*Uterine Cervical Neoplasms|Early Detection of Cancer|*DNA Methylation|Cervical Intraepithelial Neoplasia|*Cervix Uteri|Papillomavirus Infections|Human papillomavirus 18|Vaginal Smears|Human papillomavirus 16|Screening|DNA, Viral|Triage|Biomarkers, Tumor|Genotype|Precancerous Conditions 40 ASTN1 30262652 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6196552 10.1073/pnas.1811100115 7 12 0 24 Neuroglia|Neurons|Nerve Tissue Proteins|*N-Cadherin|Cell Movement|Cerebellum|Cell Adhesion|Neurogenesis|Glycoproteins|Cells, Cultured 40 ASTN1 30242134 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6187130 10.1073/pnas.1809382115 2 8 0 24 *Surface Proteins|Nerve Tissue Proteins|Neurons|*Cell Movement|*Protein Transport|Synapses|Cerebellum 40 ASTN1 29706646 Eur. J. Hum. Genet. 2018 PMC6057976 10.1038/s41431-018-0137-z 4 0 0 24 Humans|*Genomics|DNA Copy Number Variations|Malformations of Cortical Development|Phenotype|Sequencing, Whole Exome|Polymorphism, Single Nucleotide|Intellectual Disability|Epilepsy|Mutation|Cohort Studies 40 ASTN2 30392976 Stem Cell Reports 2018 PMC6235011 10.1016/j.stemcr.2018.10.003 16 1 0 61 Humans|*Autistic Disorder|Autism Spectrum Disorder|*Gene Editing|*Neurons|Induced Pluripotent Stem Cells|Postsynaptic Current, Excitatory|Cell Differentiation|Cells, Cultured|Phenotypes|Electrophysiological Phenomena|Sequencing, RNA 47 ASTN2 30242134 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6187130 10.1073/pnas.1809382115 2 8 0 61 *Surface Proteins|Nerve Tissue Proteins|Neurons|*Cell Movement|*Protein Transport|Synapses|Cerebellum 47 ASTN2 30112632 Mol. Neurobiol. 2018 PMC6476862 10.1007/s12035-018-1298-z 1 0 0 61 Humans|*Alzheimer Disease|Single Nucleotide Polymorphisms|Allele|Genetic Predisposition to Disease|Age of Onset|Genotype|*Genomics|Apolipoproteins E|Genome-Wide Association Study|Gene Frequency|Pedigree|Case-Control Studies|Mutation|*Neuroplasticity|Cognition|Colombia 47 ASTN2 29803967 Stem Cell Res 2018 10.1016/j.scr.2018.05.013 3 0 0 61 Humans|*Induced Pluripotent Stem Cells|*Schizophrenia|Neurogenesis|Transcription Factors|Brain|Exons|ASTN2 protein, human|Glycoproteins|Nerve Tissue Proteins 47 ASXL3 30508507 Clin. Chim. Acta 2018 10.1016/j.cca.2018.11.035 0 0 0 48 Humans|*Congenital Hypothyroidism|*Whole Exome Sequencing|*Thyroid Dysgenesis|Dual Oxidases|Phenotype|Genotype|Mutation 49 ASXL3 30359545 Cancer Biol. Ther. 2018 PMC6422476 10.1080/15384047.2018.1532558 0 0 0 48 Humans|*Imatinib Mesylate|*Point Mutation|*Genetic Heterogeneity|mRNA Cleavage and Polyadenylation Factors|Receptor, Platelet-Derived Growth Factor alpha|Hypereosinophilic Syndrome|Piperazines|Benzamides|Pyrimidines|Oncogene Proteins, Fusion|Antineoplastic Agents|Mutations|*Receptor Protein-Tyrosine Kinases|*Leukocyte Disorders|Exon|ASXL3 protein, human|Transcription Factors 49 ASXL3 30349006 Nat Commun 2018 PMC6197237 10.1038/s41467-018-06854-2 1 4 0 48 Animals|*Ubiquitination|Ubiquitin Thiolesterase|Tumor Suppressor Proteins|Repressor Proteins|Histones|Ubiquitin|Transcription Factors|Mesothelioma, Malignant|Lung Neoplasms|Cell Proliferation|*Genes, Tumor Suppressor|Signal Transduction|Mesothelioma 49 ASXL3 29982334 Endocrinology 2018 10.1210/en.2018-00246 2 0 0 48 *Parathyroid Neoplasms|*Whole Exome Sequencing|Hyperparathyroidism, Primary|Adenoma|Mutation|Carcinomas 49 ASXL3 29628764 Neuropsychiatr Dis Treat 2018 PMC5877499 10.2147/NDT.S153511 0 0 0 48 Child|Male|Humans|Aged|Developmental Disabilities|*Epilepsy|Phenotype|Heterozygote|Transcription Factors|Failure to Thrive|Mutation|Syndrome 49 ASXL3 29445472 Clin Case Rep 2018 PMC5799615 10.1002/ccr3.1361 2 0 0 48 Child|Humans|Male|*Frameshift Mutation|Developmental Disabilities|Heterozygote|Phenotype|Failure to Thrive|Mutation|Transcription Factors|Syndrome 49 ASXL3 29429203 Zhonghua Er Ke Za Zhi 2018 10.3760/cma.j.issn.0578-1310.2018.02.013 1 0 0 48 49 ASXL3 29428674 Biol. Psychiatry 2018 10.1016/j.biopsych.2018.01.002 5 0 0 48 49 ASXL3 29367179 Epilepsy Res. 2018 10.1016/j.eplepsyres.2018.01.014 0 0 0 48 49 ASXL3 29316359 Birth Defects Res 2018 10.1002/bdr2.1191 2 0 0 48 49 ATG2A 30258221 Sci Rep 2018 PMC6158263 10.1038/s41598-018-32560-6 0 0 0 102 *Lipid Droplets|*Hepatic Stellate Cells|*Biological Phenomena|*Autophagy|*Inhibition, Psychological 30 ATG2A 30185561 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6196511 10.1073/pnas.1811874115 24 1 0 102 Humans|*Autophagosomes|Autophagy-Related Proteins|Endoplasmic Reticulum|Phosphatidylinositol Phosphates|Saccharomyces cerevisiae Proteins|Membrane Proteins|Autophagy|Carrier Proteins|Membrane|Lysosomes|Lipid Metabolism 30 ATG2A 29915313 Sci Rep 2018 PMC6006255 10.1038/s41598-018-27686-6 4 9 0 102 Humans|Mice|Animals|*Lipid Droplet|*Hepatic Stellate Cells|*Autophagy|Fibrosis, Liver|Carbon Tetrachloride|Downregulation|Cells, Cultured|Liver|Lipid Metabolism|Upregulation|Retinol|Cell Line|Actins|Proteins, Lipid Droplet 30 ATG2A 29346025 Lymphat Res Biol 2018 10.1089/lrb.2017.0033 5 1 0 102 *Endothelial Cells|*Alleles|PIK3CA protein, human|*Class I Phosphatidylinositol 3-Kinases|Aminoimidazole Carboxamide|*Lymphatic Abnormalities|Ribonucleotides|AMP-Activated Protein Kinases|Cell Line|Phenotype|*Genetic Linkage|Mutation 30 ATG2B 30093493 J. Cell Biol. 2018 PMC6168267 10.1083/jcb.201807019 55 3 0 89 Humans|*Transport Proteins|*Mitochondrial Membranes|Endosomes|Vesicular Transport Proteins|Chorea-Acanthocytosis|Lysosomes|*Biological Transport|Endoplasmic Reticulum|Lipid Droplets|Mitochondria|Autophagy|Saccharomyces cerevisiae|*Lipids|Homeostasis|VPS13A protein, human|VPS13C protein, human|Proteins|VPS13 protein, S cerevisiae 48 ATG2B 29562274 Inflamm. Bowel Dis. 2018 10.1093/ibd/izx075 3 6 0 89 Humans|*Crohn Disease|*Autophagy|Autophagy-Related Proteins|RNA, Micro|Colitis, Ulcerative|Intestinal Mucosa|Vesicular Transport Proteins|Up-Regulation|ATG2B protein, human|MIRN143 microRNA, human 48 ATG2B 29454863 J Thorac Oncol 2018 PMC6124306 10.1016/j.jtho.2018.01.028 6 10 0 89 Humans|*Carcinoma, Non-Small-Cell Lung|*Radiation Pneumonitis|*Lung Neoplasms|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|DNA-Binding Proteins|Risk Factors 48 ATG2B 29346025 Lymphat Res Biol 2018 10.1089/lrb.2017.0033 5 1 0 89 *Endothelial Cells|*Alleles|PIK3CA protein, human|*Class I Phosphatidylinositol 3-Kinases|Aminoimidazole Carboxamide|*Lymphatic Abnormalities|Ribonucleotides|AMP-Activated Protein Kinases|Cell Line|Phenotype|*Genetic Linkage|Mutation 48 ATL2 30215537 Epigenomics 2018 10.2217/epi-2017-0173 8 4 0 95 *Stomach Neoplasms|*RNA, Circular|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|*Neoplastic Processes|*Stomach|Cell Line, Tumor|Down-Regulation 23 atoh7 30541618 Neural Dev 2018 PMC6291928 10.1186/s13064-018-0124-7 1 0 0 163 Mice|Animals|*Geniculate Bodies|*Retina|Visual Pathways|Retinal Ganglion Cells|Transgenic Mouse|*Brainstem|Cholinergic Agents 174 atoh7 30519491 Genet Res Int 2018 PMC6241241 10.1155/2018/2148056 2 0 0 163 Glaucoma, Open-Angle|Gene Frequency|Study, Genetic Association|Intraocular Pressure|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Study|Alleles|Genotype 174 atoh7 30405695 Front Genet 2018 PMC6208000 10.3389/fgene.2018.00488 1 0 0 163 Humans|Glaucoma, Primary Open Angle|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Intraocular Pressure|Genotype|Visual Field|Cyclin-Dependent Kinase Inhibitor p15|Homeodomain Proteins 174 atoh7 30337377 Development 2018 PMC6240314 10.1242/dev.169698 1 1 0 163 Animals|*Retina|*Signal Transduction|Basic Helix-Loop-Helix Transcription Factors|Receptors, Notch|Cell Differentiation|Neurogenesis|Cell Lineage|Retinal Ganglion Cells|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Neuroglia|Medaka 174 atoh7 30208054 PLoS ONE 2018 PMC6135365 10.1371/journal.pone.0202867 0 0 0 163 Mice|Animals|*Retina|Retinal Ganglion Cell|Basic Helix-Loop-Helix Transcription Factors|Transcription Factor|Cell Differentiation|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Neurogenesis|Cell Lineage|Embryo, Mammalian|Progenitor Cells|Ganglia|Trim9 protein, mouse|Carrier Proteins 174 atoh7 30073347 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24236 1 0 0 163 *Organogenesis|Eye Proteins|Microphthalmia|Homeodomain Proteins|Coloboma|Anophthalmia|Gene Expression Regulation, Developmental|Eye Abnormalities|Retina|Morphogenesis|Intracellular Signaling Peptides and Proteins|Cell Proliferation 174 atoh7 29977079 Sci Rep 2018 PMC6033939 10.1038/s41598-018-28420-y 0 29 0 163 Mice|Animals|Retina|Retinal Ganglion Cells|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Cell Differentiation|Gene Expression Regulation, Developmental|Receptors, Notch|Nerve Tissue Proteins|Embryo, Mammalian|Signal Transduction|Progenitor Cells|Chromatin Immunoprecipitation|Atoh7 protein, mouse|Rbpj protein, mouse|Immunoglobulin J Recombination Signal Sequence-Binding Protein 174 atoh7 29936090 Methods 2018 PMC6296225 10.1016/j.ymeth.2018.06.008 3 1 0 163 Animals|Humans|*Zebrafish|Zebrafish Proteins|Embryo, Nonmammalian|*Neuroanatomy|*Brain|Autism|Gene Expression Regulation, Developmental|Gene Knockdown|Valproic Acid|Behavior, Animal|Larvae|Neurogenesis|Phenotypes 174 atoh7 29792847 Exp. Eye Res. 2018 10.1016/j.exer.2018.05.021 0 0 0 163 Humans|Aged|ACE protein, human|*Angiotensin Converting Enzyme|*Optic Neuropathy, Ischemic|*Endothelin-1|Case-Control Studies|Single Nucleotide Polymorphisms|Genotype|Allele|Hypertension|Polymerase Chain Reaction 174 atoh7 29770538 Dev. Dyn. 2018 PMC6105502 10.1002/dvdy.24638 2 2 0 163 Mice|Animals|*Cell Differentiation|*Cell Cycle|Neurogenesis|Basic Helix-Loop-Helix Transcription Factors|Retina|*Cell Division|Nerve Tissue Proteins|Cell Lineage|Gene Expression Regulation, Developmental|Retinal Ganglion Cells|Transcription Factor|Embryo, Mammalian|Progenitor Cells|3'-(1-butylphosphoryl)adenosine|Phenotypes|Neurog2 protein, mouse 174 atoh7 29717171 Sci Rep 2018 PMC5931526 10.1038/s41598-018-25188-z 2 15 0 163 Mice|Animals|Humans|*Retinal Ganglion Cells|Basic Helix-Loop-Helix Transcription Factors|Retina|Cell Differentiation|*M Phase|Cell Lineage|Cell Cycle|Gene Expression Regulation, Developmental|Neurogenesis|Nerve Tissue Proteins|Transcription Factor|Stem Cell|Mice, Transgenic|Embryo, Mammalian|ATOH7 protein, human|Atoh7 protein, mouse 174 ATRN 30280706 J Vector Borne Dis 2018 10.4103/0972-9062.242569 0 0 0 64 Animals|Anopheles|Insect Proteins|Smell 82 ATRN 29792933 Nitric Oxide 2018 10.1016/j.niox.2018.05.007 0 0 0 64 Rats|Animals|NOS1 protein, human|*Nitric Oxide Synthase Type I|*Dopamine|Tyrosine Hydroxylase|Dopaminergic Neurons|Substantia Nigra|Substantia Nigra Pars Compacta|Neostriatum|Neuroprotective Effects|7-nitroindazole|Indazoles 82 ATRN 29695737 Sci Rep 2018 PMC5916935 10.1038/s41598-018-24270-w 3 0 0 64 Humans|Male|*Prostatic Hyperplasia|*Proteomics|kallikrein-related peptidase 3, human|Prostate Specific Antigen|*Prostate Cancer|Prostate|Kallikreins|*Affinity Chromatography|leukoagglutinins, plants|Phytohemagglutinins|Lectins|lectin B, Phytolacca americana|*Pokeweed Mitogens|erythroagglutinating phytohemagglutinin|Serum Proteins|Protein Glycosylation|Mass Spectrometry|ATRN protein, human 82 ATRN 29559925 Front Physiol 2018 PMC5845533 10.3389/fphys.2018.00172 3 12 0 64 Cattle|Animals|ASIP protein, human|*Agouti Signaling Protein|Adipose Tissue|Adipocytes|Receptors, Melanocortin|RNA, Messenger|Fatty Acids|Muscle, Skeletal|Muscle Fibers, Skeletal|ATRN protein, human|Membrane Proteins|*Biomarkers 82 ATRNL1 30018746 Oncotarget 2018 PMC6044373 10.18632/oncotarget.25673 8 10 0 17 30 ATRNL1 29932237 J. Cell. Biochem. 2018 10.1002/jcb.27060 1 1 0 17 30 ATRNL1 29904917 J. Cell. Physiol. 2018 10.1002/jcp.26841 2 3 0 17 30 ATRNL1 29494810 Arch. Oral Biol. 2018 10.1016/j.archoralbio.2017.12.027 1 0 0 17 30 ATRNL1 29438885 Int. Immunopharmacol. 2018 10.1016/j.intimp.2018.02.002 0 7 0 17 30 BANK1 30145638 Clin. Rheumatol. 2018 10.1007/s10067-018-4257-1 0 0 0 136 Humans|*Dermatomyositis|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Polymyositis|Genetic Predisposition to Disease|Gene Frequency|Genetic Association Studies|Allele|Genotype|Case-Control Studies|BANK1 protein, human|Membrane Proteins|Adaptor Proteins, Signal Transducing 86 BANK1 30096841 Int J Mol Sci 2018 PMC6121630 10.3390/ijms19082331 3 5 0 136 86 BANK1 30016332 PLoS ONE 2018 PMC6049909 10.1371/journal.pone.0199979 2 3 0 136 Humans|Mice|Animals|Genome-Wide Association Study|*NF-kappa B|Antinuclear Antibodies|Autoimmune Responses|RELA protein, human|*Transcription Factor RelA|Autoantibodies|Autoimmune Diseases|B Cells|Mercury|Haplotype|Gene Expression|Quantitative Trait Locus|Immunoglobulin G|*Cell Nucleolus|Spleen|BANK1 protein, human|Membrane Proteins 86 BANK1 29608557 PLoS Genet. 2018 PMC5897035 10.1371/journal.pgen.1007222 6 0 0 136 Animals|Humans|*Body Mass Index|*Drosophila melanogaster|*Genome-Wide Association Study|*RNA Interference|SNPs|Obesity|Quantitative Trait Loci|Phenotype|Genetic Predisposition to Disease|Adipose Tissue|Adiposity|ARIH1 protein, human|Carrier Proteins|ZCCHC8 protein, human|Nuclear Proteins|VKORC1 protein, human|Vitamin K Epoxide Reductases 86 BANK1 29370826 Arthritis Res. Ther. 2018 PMC5785884 10.1186/s13075-017-1503-x 1 8 0 136 Mice|Animals|*Arthritis, Experimental|*T-Lymphocytes, Regulatory|*B Cells|Rheumatoid Arthritis|Cytokines|Mice, Inbred DBA|Spleen|BANK1 protein, mouse|Adaptor Proteins, Signal Transducing 86 BARHL1 29413750 Int. J. Biochem. Cell Biol. 2018 10.1016/j.biocel.2018.01.013 1 1 0 73 Animals|Mice|*Mouse Embryonic Stem Cells|*Hair Cells, Auditory, Inner|*Cell Differentiation|Hair Cells, Auditory|Homeobox Gene|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Repressor Proteins|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Cochlea|Hearing|Cell Line|Barhl1 protein, mouse 35 BARX1 30583699 J. Dent. Res. 2018 10.1177/0022034518811861 1 0 0 95 Humans|Mice|Animals|Palate|PAX1 transcription factor|Paired Box Transcription Factors|Cleft Palate|Gene Expression Regulation, Developmental|Morphogenesis|Mesenchyme|Wnt Pathways|Cell Proliferation|In Situ Hybridization|PAX9 protein, human|PAX9 Transcription Factor|Ldb1 protein, mouse|DNA-Binding Proteins|LIM Domain Proteins 100 BARX1 30443989 Cell Prolif. 2018 PMC6430486 10.1111/cpr.12522 1 3 0 95 *Osteogenesis|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|*Mesenchymal Stem Cells|*Cell Differentiation|Bone Marrow Cells|Bone Regeneration|Calcification, Physiologic|Bone Tissue|Homeodomain Proteins|Transcription Factors|Cells, Cultured|Tissue Engineering|Signal Transduction|Alkaline Phosphatase 100 BARX1 30378758 Wiley Interdiscip Rev Dev Biol 2018 10.1002/wdev.337 2 2 0 95 Animals|*Jaw|Vertebrates|Homeodomain Proteins|Hox Genes|Pharyngeal Arches|Body Patterning|Transcription Factors|*Fishes|Neural Crest|Gene Expression Regulation, Developmental|Biological Evolution|Fossils|Pharynx|Bone|Mammals|Cartilage 100 BARX1 30281099 Hum. Mol. Genet. 2018 PMC6322072 10.1093/hmg/ddy347 2 0 0 95 Infant|Humans|Pyloric Stenosis, Infantile Hypertrophic 1|*Pyloric Stenosis, Hypertrophic|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genome-Wide Association Study|Genetic Loci|Genotype|Odds Ratio|MTA3 protein, human|Neoplasm Proteins|BARX1 protein, human|Transcription Factors|Homeodomain Proteins 100 BARX1 30031117 Cancer Lett. 2018 10.1016/j.canlet.2018.07.020 5 2 0 95 Humans|Mice|Animals|*Carcinoma, Non-Small-Cell Lung|*Transcription Factors|*Lung Neoplasms|Mice, Nude|A549 Cells|Lung Adenocarcinoma|Gene Expression Regulation, Neoplastic|Short Hairpin RNA|RNA Interference|Tumor Burden|Cell Proliferation|Cell Line, Tumor|CCND1 protein, human|Cyclin D1|CBFA2T3 protein, human|Tumor Suppressor Proteins|Homeodomain Proteins|Xenograft Model Antitumor Assays 100 BARX1 29666340 J. Genet. 2018 0 0 0 95 Humans|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|*Chinese|SNPs|Genetic Predisposition to Disease|Genotype|Genome-Wide Association Study|Allele|Frequencies, Allele|Case-Control Studies|Chi-Square Test|Forkhead Transcription Factors|FOXF1 protein, human|FOXP1 protein, human|Repressor Proteins 100 BARX1 29523871 Cell Death Differ. 2018 PMC6219484 10.1038/s41418-018-0083-x 2 2 0 95 Mice|Animals|*Neural Crest|GATA4 Transcription Factor|Homeodomain Proteins|mRNA|Chromatin Immunoprecipitation|Cell Differentiation|Gene Expression Regulation, Developmental|RNA Interference|Cell Proliferation|Promoter Regions, Genetic|Cell Movement|Protein Binding|Zebrafish|Gata4 protein, mouse 100 BARX1 29454095 Cancer Lett. 2018 10.1016/j.canlet.2018.02.019 0 1 0 95 Humans|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Esophageal Squamous Cell Carcinoma|Genome-Wide Association Study|Case-Control Studies|*Adenocarcinoma|Genetic Predisposition to Disease|Carcinoma, Squamous Cell|Polymorphism, Single Nucleotide|Chinese|Allele|Genotype|Odds Ratio|BARX1 protein, human|Transcription Factors|Homeodomain Proteins 100 BASP1 30289917 PLoS ONE 2018 PMC6173434 10.1371/journal.pone.0205107 6 2 0 707 *Lung Transplantation|Bronchiolitis Obliterans|Graft Rejection|Allografts|Bronchoalveolar Lavage Fluid 136 BASP1 29674693 Exp. Mol. Med. 2018 PMC5938046 10.1038/s12276-018-0067-4 6 23 0 707 Humans|RUNX1 Translocation Partner 1 Protein|*Leukemia, Myeloid, Acute|Core Binding Factor Alpha 2 Subunit|Translocation, Genetic|Oncogene Proteins, Fusion|Gene Expression Regulation, Leukemic|*Carcinogenesis|DNA methyltransferase 3A|DNA (Cytosine-5-)-Methyltransferases|DNA Methylation|Downregulation|Apoptosis|Cell Line, Tumor|Promoter Regions, Genetic|Cell Proliferation|U937 Cells|Binding Sites|BASP1 protein, human 136 BASP1 29604406 Neurosci. Lett. 2018 10.1016/j.neulet.2018.03.061 0 7 0 707 *Dynamin I|*Neurons|Calmodulin-Binding Proteins|Cytoskeletal Proteins|Nerve Tissue Proteins|Synaptic Vesicles|Membrane Microdomains|Synaptic Membranes|Membrane Lipids|Binding Proteins|Brain|Protein Binding 136 BASP1 29584801 J Crohns Colitis 2018 PMC6279085 10.1093/ecco-jcc/jjy002 6 0 0 707 Humans|Genome-Wide Association Study|Asian|*Inflammatory Bowel Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Colitis, Ulcerative|Crohn Disease|Genetic Loci|European Continental Ancestry Group|Case-Control Studies|Genotype 136 BASP1 29523190 Stem Cell Res Ther 2018 PMC5845143 10.1186/s13287-018-0797-1 10 9 0 707 Humans|*Nucleus Pulposus|*Human Induced Pluripotent Stem Cells|Intervertebral Disk Degeneration|Notochords|Intervertebral Disc|Cell Differentiation|Chondrocytes|*Hematopoiesis|Extracellular Matrix|Phenotype|Biomarkers 136 BCORL1 30504346 Hematology Am Soc Hematol Educ Program 2018 PMC6245980 10.1182/asheducation-2018.1.457 1 0 0 82 Humans|Aged|*Anemia, Aplastic|*Clonal Evolution|Myelodysplastic Syndrome|Hemoglobinuria, Paroxysmal|Hematopoiesis|Mutation 58 BCORL1 30514397 Acta Neuropathol Commun 2018 PMC6278135 10.1186/s40478-018-0630-1 4 0 0 82 Child|Humans|Familial ependymoma|*Ependymomas|*Supratentorial Neoplasms|Glioma|Transcription Factor RelA|Brain Neoplasms|*Genes, Regulator|Oncogene Proteins, Fusion|Genetic Profile|Japan|CRIP1 protein, human|Carrier Proteins|LIM Domain Proteins|RELA protein, human|C11orf95 protein, human|Proteins 58 BCORL1 30489320 Am. 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Pathol. 2018 PMC6764762 10.1097/PAS.0000000000001196 2 0 0 82 Humans|Female|Middle Aged|*Leiomyosarcoma|In Situ Hybridization, Fluorescence|*Uterine Neoplasms|*Gene Rearrangement|Immunohistochemistry|Mitotic Index|Gene Fusion|*Uterus|HMGA2 Protein|Sequencing, RNA|Biomarkers, Tumor|*Neoplasms, Connective and Soft Tissue|Whole Exome Sequencing|Diagnosis, Differential|Phenotype|TRPS1 protein, human|DNA-Binding Proteins|Transcription Factors 58 BCORL1 30480765 Cancer 2018 PMC6587451 10.1002/cncr.31837 6 0 0 82 *Proteolysis|*Leukemia, Myeloid, Acute|*Genomics|Gene Expression Regulation, Leukemic|Prognosis|Mutation|Gene Expression Profiling|Genetic Predisposition to Disease|*Aneuploid|*Cell Cycle 58 BCORL1 30305498 Rinsho Ketsueki 2018 10.11406/rinketsu.59.1962 0 0 0 82 Humans|Aged|*Anemia, Aplastic|*Hematopoiesis|Myelodysplastic Syndrome|Hemoglobinuria, Paroxysmal|Clone Cells|Mutations|Bone Marrow Failure|Pancytopenia 58 BCORL1 30138727 J Mol Diagn 2018 10.1016/j.jmoldx.2018.07.002 3 1 0 82 Humans|*Pathology, Molecular|*Myeloproliferative Disorders|Myelodysplastic Syndromes|JAK2 protein, human|Janus Kinase 2|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|*DNA|Mutation|SETBP1 protein, human|Nuclear Proteins|Genes, Regulator|High-Throughput Nucleotide Sequencing|Neoplasm Proteins|DNA-Binding Proteins|Repressor Proteins|Signal Transduction|Neoplasms 58 BEND3 30399318 ACS Chem Neurosci 2018 10.1021/acschemneuro.8b00368 0 3 0 121 Mice|Animals|azelnidipine|*Endothelial Cells|*Azetidinecarboxylic Acid|*Dihydropyridines|Calcium Channel Blockers|*Amyloidogenic Proteins|Oxidative Stress|Reactive Oxygen Species|*Amyloidosis|Superoxide Anion|*Oxidation-Reduction|Phosphorylation 93 BEND3 30290210 Cell. Signal. 2018 10.1016/j.cellsig.2018.09.019 7 15 0 121 *Sphingosine 1 Phosphate Receptor 2|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|S1PR2 protein, human|*Receptors, Lysosphingolipid|*Oxidative Stress|*Brain|Signal Transduction|p38 Mitogen-Activated Protein Kinases|Capillary Permeability|Endothelial Cells|Phosphorylation|Pyridines|Pyrazoles|*Permeability 93 BEND3 30170602 J Neuroinflammation 2018 PMC6119285 10.1186/s12974-018-1287-1 4 2 0 121 Animals|Mice|*Tryptases|*Receptor, PAR-2|*Endothelial Cells|NF-kappa B|Interleukin-6|Signal Transduction|Endothelium|Cell Line|Brain 93 BEND3 29913220 J Control Release 2018 10.1016/j.jconrel.2018.06.021 1 1 0 121 Animals|Mice|*Blood-Brain Barrier|*Nootropic Agents|*Traumatic Brain Injury|*Permeability|Brain|*Biological Transport|Neuroprotective Agents|Poloxamer|Methylene Blue|Zonula Occludens-1 Protein|Neurons|Nanoparticles|Surface-Active Agents|Endothelial Cells|Disease Models, Animal 93 BEND3 29879439 Neurosci. Lett. 2018 PMC6102071 10.1016/j.neulet.2018.05.045 12 0 0 121 *Electronic Nicotine Delivery Systems|*Endothelium, Vascular|Endothelial Cells|Vaping|Nicotine|*Smoke|Oxidative Stress|*Brain|Reactive Oxygen Species|Blood-Brain Barrier|Smoking, Tobacco|Inflammation|Smoking|*Tobacco|Iron 93 BEND3 29683403 Neurol. Res. 2018 10.1080/01616412.2018.1460701 2 2 0 121 Animals|Mice|ABCG2 protein, human|*ATP Binding Cassette Transporter, Subfamily G, Member 2|*Neoplasm Proteins|*P Glycoprotein|Blood-Brain Barrier|*Biological Transport|*Membrane Transport Proteins|ATP-Binding Cassette Transporters|Claudin-5|Brain|Rhodamine 123|Occludin|Permeability|Mitoxantrone|Cell Line|Tight Junction Proteins|Verapamil|lucifer yellow 93 BEND3 29608400 Nucleic Acid Ther 2018 10.1089/nat.2017.0711 4 0 0 121 Humans|Mice|Animals|*Endothelial Cell|SELEX Aptamer Technique|Aptamers, Nucleotide|RNA Interference|Drug Delivery Systems|Cancer|Cell Line|*B-Lymphocytes|*Cross Reactions 93 BEND3 29493364 J Microencapsul 2018 10.1080/02652048.2018.1447615 1 2 0 121 Humans|Female|Pregnancy|*Micelles|*Clonazepam|poly(lactic acid-ethylene glycol)|Glycol, Polyethylene|*Polymers|polyethylene glycol-distearoylphosphatidylethanolamine|*Nanoparticles|Release, Drug|poly(lactide)|Polyesters|Drug Carriers|Particle Size|Phosphatidylethanolamines|Drug Compounding|Lactates|Drug Delivery Systems|carbopol 940|Acrylic Resins 93 BHLHA15 30510993 Cell Mol Gastroenterol Hepatol 2018 PMC6260375 10.1016/j.jcmgh.2018.09.004 2 8 0 200 66 BHLHA15 30448068 Gastroenterology 2018 PMC6409180 10.1053/j.gastro.2018.11.024 5 0 0 200 66 BHLHA15 29959361 Sci Rep 2018 PMC6026145 10.1038/s41598-018-28223-1 1 11 0 200 66 BHLHA15 29719936 Mol Oncol 2018 PMC6026875 10.1002/1878-0261.12314 4 29 0 200 66 BHLHA15 29411893 Anim. Genet. 2018 PMC5873431 10.1111/age.12638 9 4 0 200 66 BLID 30505443 Arch Public Health 2018 PMC6260705 10.1186/s13690-018-0317-x 2 0 0 49 Humans|*Housing|*Homelessness|Europe|*Survey|Financing, Personal|*Social Problems|*Knowledge|Mental Disorders|*Attitudes 187 BLID 30195794 Mol Ther Nucleic Acids 2018 PMC6077131 10.1016/j.omtn.2018.06.011 4 5 0 49 *Tumorigenesis|MicroRNAs|*Cell Transformation, Neoplastic|Gastric Cancer|Doxorubicin|Gene Expression Regulation, Neoplastic|Cell Proliferation|Drug Resistance, Neoplasm|Antibiotics, Antineoplastic|Cell Line, Tumor|Down-Regulation|3' Untranslated Regions|Apoptosis|Cell Movement|Antineoplastic Agents|Phosphorylation 187 BLID 30161284 Angew. Chem. Int. Ed. Engl. 2018 PMC6330212 10.1002/anie.201806909 1 0 0 49 Protein Structure, Secondary|Peptides|Amino Acid Sequence|Amino Acids|bcl-X Protein|Peptide Fragments|Circular Dichroism 187 BLID 29518473 Toxicol. Lett. 2018 10.1016/j.toxlet.2018.03.003 1 4 0 49 Humans|*DNA Methylation|cyanoginosin LR|microcystin|*Microcystins|*Leucine|Epigenesis, Genetic|*Arginine|MIRN331 microRNA, human|*miRNA|*Hepatocyte|Hepatocellular Carcinoma|*Cell Transformation, Neoplastic|*Network, Gene|Liver Neoplasms|MAGED1 protein, human|Neoplasm Proteins|Carcinogenesis|Liver 187 BMP2K 29685905 Mol. Cell. Biol. 2018 PMC6024166 10.1128/MCB.00590-17 1 3 0 204 IRS2 protein, human|*Insulin Receptor Substrate Proteins|Phosphatidylinositol 3-Kinases|Signal Transduction|Phosphatidylinositol 3-Kinase|Proto-Oncogene Proteins c-akt|Receptor, IGF Type 1|Phosphorylation|Insulin|Glucose|Glycolysis|Biological Transport 23 BMP8B 30496795 Biochim Biophys Acta Mol Basis Dis 2018 PMC6364553 10.1016/j.bbadis.2018.11.004 3 2 0 137 Mice|Animals|*3T3-L1 Cells|*Troglitazone|*Peroxisome Proliferator-Activated Receptor gamma|TRPV1 receptor|*TRPV Cation Channels|Adipogenesis|Adipose Tissue, White|Adipocytes|Capsaicine|Thermogenesis|2,4-thiazolidinedione|Thiazolidinediones|Diet, High-Fat|Obesity|Cell Differentiation|TRPV1 protein, mouse 74 BMP8B 30478315 Nat Commun 2018 PMC6255810 10.1038/s41467-018-07453-x 17 0 0 137 Adipose Tissue, Brown|Thermogenesis|Adipocytes, Beige|Adipocytes, Brown|neuregulin-4|Neuregulins|Adipose Tissue, White|Obesity|Energy Metabolism|*Norepinephrine|Signal Transduction|Adrenergic Agents 74 BMP8B 30325584 Birth Defects Res 2018 10.1002/bdr2.1406 0 0 0 137 Mice|Animals|*Valproic Acid|valnoctamide|*Amides|Anticonvulsants|Abnormalities, Drug-Induced|*Teratogenesis|Teratogens|Neural Tube Defects|*Isomerism|Structure-Activity Relationship 74 BMP8B 30049662 Ann. Anat. 2018 10.1016/j.aanat.2018.06.004 3 0 0 137 UCP1 protein, human|Thermogenin|Adipose Tissue, White|Thermogenesis|Adipose Tissue, Brown|Adipose Tissue, Beige|*Obesity|Adipogenesis|Adipocytes, Brown|Adipocytes, White|Leptin|Lipolysis|Lipogenesis|Cell Transdifferentiation|BMP7 protein, human|Bone Morphogenetic Protein 7|Body Temperature Regulation|Cell Differentiation 74 BMP8B 29386003 BMC Med. Genet. 2018 PMC5793349 10.1186/s12881-018-0537-5 2 1 0 137 Humans|Female|*Whole Exome Sequencing|*Leiomyoma, Uterine|Uterine Neoplasms|*Lung|*Mutation|Lung Neoplasms|BMP8B protein, human|Bone Morphogenetic Proteins 74 BMPER 30496196 PLoS ONE 2018 PMC6264504 10.1371/journal.pone.0207504 0 0 0 173 *Epithelial-Mesenchymal Transition|Carrier Proteins|Signal Transduction 86 BMPER 30478225 Development 2018 10.1242/dev.171827 0 14 0 173 Mice|Animals|*Wnt Signaling Pathway|*Mesenchyme|*Cell Differentiation|Bone Morphogenetic Protein 4|Hedgehog Proteins|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Morphogenesis|Ureter|Smooth Muscle Cells|Cell Proliferation|Transcription Factors|Tbx3 protein, mouse 86 BMPER 30231021 PLoS Genet. 2018 PMC6166978 10.1371/journal.pgen.1007661 4 3 0 173 Swine|Pregnancy|Mice|Animals|Lethal Allele|Homozygote|Breeding|Phenotype|Allele Frequency|Sus scrofa|Haplotypes|Genes, Recessive|Heterozygotes|Genotype|Alleles|Fertility|Genes, Regulator|Genomics|BBS9 protein, mouse|Microtubule-Associated Proteins 86 BMPER 30125619 Matrix Biol. 2018 PMC6456722 10.1016/j.matbio.2018.08.006 1 8 0 173 Humans|Animals|*Gastrulation|*Bone Morphogenetic Proteins|BMP4 protein, human|Bone Morphogenetic Protein 4|Signal Transduction|Zebrafish Proteins|Carrier Proteins|Neovascularization, Physiologic|Protein Binding|Zebrafish|Endothelial Cells|Cells, Cultured|BMPER protein, human 86 BMPER 30006055 Eur J Med Genet 2018 10.1016/j.ejmg.2018.07.004 2 1 0 173 Female|Pregnancy|Humans|Diaphanospondylodysostosis|*Dysostoses|*Craniofacial Abnormalities|*Ribs|*Spine|*Prenatal Diagnosis|Homozygote|*Rare Disease|Mutation|Carrier Proteins|*Musculoskeletal System|BMPER protein, human 86 BMPER 29654706 FEBS J. 2018 PMC5947552 10.1111/febs.14439 1 2 0 173 Animals|*Bone Morphogenetic Proteins|*Endothelial Cell|*Signal Transduction|*Cell Differentiation|Receptor, BMP|Zebrafish Proteins|Carrier Proteins|Neovascularization, Physiologic|Zebrafish|Ephrin-B2|RNA, Small Interfering 86 BMPER 29518774 Cell. 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Mol. Genet. 2018 10.1093/hmg/ddy261 5 0 0 179 Female|Mice|Animals|Humans|*Primary Ovarian Insufficiency|*Menopause, Premature|HEK293 Cells|Sequencing, Whole Exome|Pedigree|Mutation|Heterozygote|Missense Mutation|Ovary|Chinese|Bnc1 protein, mouse|DNA-Binding Proteins|Transcription Factors 94 bnc1 29741885 Biochemistry 2018 PMC6034166 10.1021/acs.biochem.8b00406 1 3 0 179 *Nitrogen|*Carbon|ethylenediamine|*Ethylenediamines|Succinates|Ethylenediaminetetraacetic Acid|Chelating Agents|Biodegradation, Environmental|*Lyases|*Catalysis|Aspartic Acid 94 BNC2 30549996 Clin. Lab. 2018 10.7754/Clin.Lab.2018.180537 1 0 0 85 *RNA, Long Noncoding|*Stomach Neoplasms|Cell Proliferation|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|*Stomach|MicroRNAs|Cell Line, Tumor|RNA, Small Interfering|*Neoplastic Processes|Neoplasm Staging|Transfection 77 BNC2 30487138 Cancer Res. 2018 PMC6359979 10.1158/0008-5472.CAN-17-3864 1 0 0 85 Humans|Female|Genome-Wide Association Study|Carcinoma, Ovarian Epithelial|SNPs|Genetic Predisposition to Disease|Ovarian Cancer|*Ovary|Genotype|Allele|DNA-Binding Proteins 77 BNC2 30402331 Immune Netw 2018 PMC6215901 10.4110/in.2018.18.e36 2 0 0 85 Humans|*Kidney Transplantation|Republic of Korea|*Immune Tolerance|Immunosuppression|Transplantation Tolerance|Immunosuppressive Agents|B Cells|Biomarkers|T Cells|Lymphocyte Count|Gene Expression Profiling 77 BNC2 30234802 Spine 2018 10.1097/BRS.0000000000002866 0 0 0 85 Humans|Adolescent|*Scoliosis|*Genome-Wide Association Study|*Chinese|Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Homeodomain Proteins|Genotype|*Disease Progression|*Kyphosis|Case-Control Studies|Transcription Factors 77 BNC2 29974532 Photodermatol Photoimmunol Photomed 2018 10.1111/phpp.12412 3 1 0 85 Spain|Studies, GWA|Melanoma|Hair Color|Skin Neoplasms|Polymorphism, Single Nucleotide|Skin Pigmentation|Genetic Predisposition to Disease|Genotype|*Photosensitivity Disorders|Alleles|Phenotype|Case-Control Studies|Sunlight 77 BNC2 29895819 Sci Rep 2018 PMC5997657 10.1038/s41598-018-27145-2 2 10 0 85 Humans|Female|*Genome-Wide Association Study|Japan|Quantitative Trait Loci|*Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Linkage Disequilibrium|MSI2 protein, human|RNA-Binding Proteins 77 BNC2 29879932 BMC Cancer 2018 PMC5992702 10.1186/s12885-018-4567-3 0 4 0 85 Humans|*Papillomavirus Infections|*Oropharyngeal Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Papillomaviridae|Human papillomavirus 16|Head and Neck Neoplasms|Carcinoma, Squamous Cell|*Mouth Neoplasms|DNA Methylation|Cohort Studies|High-Throughput Nucleotide Sequencing 77 BNC2 29855589 Sci Rep 2018 PMC5981322 10.1038/s41598-018-26880-w 0 1 0 85 Cleft Lip|*Genome-Wide Association Study|Velopharyngeal Insufficiency|Cleft Palate|Palate, Soft|Pharynx|Speech 77 BNC2 29549362 Sci Rep 2018 PMC5856832 10.1038/s41598-018-22552-x 4 2 0 85 Humans|Adolescent|*Scoliosis|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|*Kyphosis|Case-Control Studies|Ethnic Groups|Cohort Studies|BNC2 protein, human|DNA-Binding Proteins 77 BRAC1 30405761 Oncol Lett 2018 PMC6202495 10.3892/ol.2018.9473 0 1 0 0 Humans|FLNA protein, human|*Filamins|BRCA1 protein, human|*BRCA1 Protein|Cell Line, Tumor|Genes, BRCA1|Cell Movement|RNA Interference|Immunohistochemistry|MCF-7 Cells|Cell Proliferation|Actin|*Neoplastic Processes 40 BRSK1 30196145 Neurochem. Int. 2018 10.1016/j.neuint.2018.08.014 0 18 0 135 Animals|Rats|EPHA5 protein, human|*Receptor, EphA5|*Methylation|*Promoter Regions, Genetic|*Neurogenesis|PC12 Cells|Cell Differentiation|Neurons|Nerve Growth Factor|Sp1 Transcription Factor|Gene Expression Regulation|mRNA|Signal Transduction|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|3'-(1-butylphosphoryl)adenosine|*Complement Factor B 48 BRSK1 29698519 PLoS ONE 2018 PMC5919486 10.1371/journal.pone.0196698 0 0 0 135 Animals|Humans|Infant, Newborn|Neurons|Neurogenesis|STK11 protein, human|Protein-Serine-Threonine Kinases|Axons|Neocortex|Hippocampus|Cell Polarity|Progenitor Cells|*Apoptosis|Cell Differentiation|Gene Expression Regulation, Developmental|Cell Movement|Cells, Cultured|Embryo, Mammalian 48 BRWD3 30086552 Cytogenet. Genome Res. 2018 10.1159/000491871 1 0 0 50 Male|Humans|Child|Adolescent|Young Adult|Adult|*Siblings|Intellectual Disability|Comparative Genomic Hybridization|Chromosomes, Human, X|Phenotype|*Obesity|DNA Copy Number Variations|Hearing Loss|Epilepsy|Ulk4 protein, human|Protein-Serine-Threonine Kinases|BRWD3 protein, human|Transcription Factors 25 Bsx 30253177 Int. J. Biol. Macromol. 2018 10.1016/j.ijbiomac.2018.09.106 1 0 0 24 *Enzymes, Immobilized|*Cellulase|*Magnetite Nanoparticles|Rhodothermus marinus|Enzyme Stability|Endo-1,4-beta Xylanases|Hydrolysis|Cellulases|Glutaraldehyde|Hydrogen-Ion Concentration|Biomass|Bacillus|Kinetics|Temperature|Cross-Linking Reagents 86 Bsx 30225518 J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 2018 10.1007/s00359-018-1288-7 1 0 0 24 Animals|*Oncorhynchus mykiss|*Oleic Acid|*Glucose|*Transcription Factors|*Hypothalamus|Fatty Acids|Fish Proteins|Neuropeptides|Eating|Caprylates|RNA, Messenger 86 Bsx 29945867 Development 2018 10.1242/dev.163477 5 0 0 24 Animals|Zebrafish|Zebrafish Proteins|Epithalamus|Pineal Gland|Habenular Nuclei|Body Patterning|Gene Expression Regulation, Developmental|Transcription Factors|Signal Transduction|*Neurogenesis 86 Bsx 29886215 Ann Vasc Surg 2018 10.1016/j.avsg.2018.04.014 1 0 0 24 Humans|Aged|*Femoral Artery|*Drug-Eluting Stents|Popliteal Artery|Blood Vessel Prosthesis|Intermittent Claudication|Blood Vessel Prosthesis Implantation|Peripheral Arterial Disease|Vascular Patency|Polytetrafluoroethylene|Endovascular Procedures|Graft Occlusion, Vascular|Prosthesis Design|Limb Salvage|Heparin|Coated Materials, Biocompatible|Anticoagulants|Kaplan-Meier Estimate 86 Bsx 29869716 Cell Tissue Res. 2018 10.1007/s00441-018-2859-1 5 0 0 24 Rats|Mice|Animals|*Hypothalamus|*Neuroendocrine System|*Neurons|Supraoptic Nucleus|Paraventricular Hypothalamic Nucleus|transcription factor Brn-2|Homeodomain Proteins|Pituitary Gland, Posterior|POU Domain Factors|Arcuate Nucleus|Medial Eminence|Axons|*Mammals|Transcription Factors|Sim1 protein, mouse|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Dbx1 protein, mouse 86 BTBD9 30536387 Transfusion 2018 10.1111/trf.15075 2 1 0 90 Humans|*Blood Donors|Denmark|Ferritins|Anemia, Iron-Deficiency|Hepcidins|Hemochromatosis Protein|*Complement Factor B|Iron|Serine Endopeptidases|Single Nucleotide Polymorphisms|Hemoglobins|Membrane Proteins|3'-(1-butylphosphoryl)adenosine 67 BTBD9 30111810 Sci Rep 2018 PMC6093889 10.1038/s41598-018-30665-6 4 9 0 90 *Restless Legs Syndrome|*Genes, Homeobox|Genome-Wide Association Study|*Transcription Factor, Meis1|Transcription Factors|MAP Kinase Kinase 5|Homeodomain Proteins|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Neoplasm Proteins|Haplotype|Case-Control Studies 67 BTBD9 29587340 Medicines (Basel) 2018 PMC6023503 10.3390/medicines5020027 2 4 0 90 67 BTG4 30478191 EMBO J. 2018 PMC6293276 10.15252/embj.201899333 9 1 0 17 Mice|Animals|*Oocyte|Oogenesis|Meiosis|mRNA deadenylase|Ribonucleases|Cell Cycle Proteins|Transcription Factors|RNA, Messenger|Transcription, Genetic|Gene Expression Regulation, Developmental 40 BTG4 30335155 Nucleic Acids Res. 2018 PMC6326793 10.1093/nar/gky971 0 0 0 17 Mice|Animals|*Oocyte|Polyadenylation|Oogenesis|mRNA Cleavage and Polyadenylation Factors|mRNA, Maternal|Meiosis|mRNA|3' UTRs|Protein Biosynthesis|Cytoplasm|Transcription Factors|Cpeb1 protein, mouse 40 C1QTNF3 30557342 PLoS ONE 2018 PMC6296499 10.1371/journal.pone.0208038 1 0 0 239 Female|*Coronary Artery Disease|CCL2 protein, human|*Monocyte Chemoattractant Protein-1|Diabetes Mellitus, Type 2|Egypt|*Postmenopause|Adiponectin|Biomarkers|Inflammation|Tumor Necrosis Factor-alpha|Complement, C1q|Cytokines 73 C1QTNF3 30407523 Cardiovasc. Res. 2018 10.1093/cvr/cvy279 6 2 0 239 Mice|Animals|*Complement C1q|*Cardiac Hypertrophy|Signal Transduction|Adipokine|Diabetic Cardiomyopathy|Disease Models, Animal|Tumor Necrosis Factors 73 C1QTNF3 30072126 Am. J. Cardiol. 2018 10.1016/j.amjcard.2018.06.024 0 1 0 239 Humans|*Complement C1q|*Aneurysm, Dissecting|Aortic Aneurysm|Interleukin 6|Tumor Necrosis Factor-alpha|C-Reactive Protein|Adipocytokines|Inflammation|Case-Control Studies|Hypertension|Risk Factors|*Biomarkers, Tumor 73 C1QTNF3 29973485 Genes (Basel) 2018 PMC6070815 10.3390/genes9070336 5 5 0 239 Swine|Animals|*Transcriptome Analysis|*Adipose Tissue|*Signal Transduction|Sequencing, RNA|*Cyclic AMP|Transcriptome|Gene Regulatory Networks|Animal Feed|RNA, Long Noncoding|Gene Annotations 73 C1QTNF3 29944106 J Biomed Nanotechnol 2018 10.1166/jbn.2018.2563 3 3 0 239 Animals|Rats|*Silver|*Blood-Brain Barrier|*Metal Nanoparticles|*Rats, Sprague-Dawley|*Hippocampus|*Biological Transport|*Permeability|Brain|*Neurotoxicity Syndromes|Astrocyte|Transmission Electron Microscopy|alanylglutamine|Dipeptides|Tight Junction|Signal Transduction|Cognition 73 C1QTNF3 29862443 Obes Surg 2018 10.1007/s11695-018-3306-9 0 0 0 239 *Gastrectomy|*Obesity|Weight Reduction|Obesity, Morbid|Insulin Resistance|Body Mass Index|Insulin|Blood Glucose|Laparoscopy|Adipokine 73 C1QTNF6 30431096 Int. 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Res. 2018 10.1002/jnr.24353 0 0 0 1 *Complement C1q|Endothelial Cells|*Brain Ischemia|*Stroke|TNF protein, human|*Tumor Necrosis Factor-alpha|TYRP1 protein, human|*Membrane Glycoproteins|Adiponectin|Glycoproteins|Tumor Necrosis Factor Receptor-Associated Peptides and Proteins|Atherosclerosis|Adipokine|Signal Transduction|*Lymphotoxin-alpha|Coronary Artery Disease 38 C1QTNF9B 30226624 Oncol. Rep. 2018 10.3892/or.2018.6677 1 0 0 1 Humans|*Urinary Bladder Neoplasms|*Transcriptome|*Prognosis|Long Non-Coding RNA|Kaplan-Meier Estimate|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Proportional Hazards Models|MicroRNAs|Databases, Genetic|ROC Curve 38 C1QTNF9B 30056359 Atherosclerosis 2018 10.1016/j.atherosclerosis.2018.07.022 2 4 0 1 Humans|Animals|*Complement C1q|Receptors, Adiponectin|*Atherosclerosis|Adiponectin|Glycoproteins|Signal Transduction|Inflammation|Protein Isoforms|Proteolysis|N-Cadherin|Tumor Necrosis Factors 38 C1QTNF9B 29979351 J. 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Pharmacol. 2018 PMC6181274 10.1097/FJC.0000000000000612 2 4 0 1 *Foam Cells|*Complement C1q|ABCG1 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 1|ABCA1 protein, human|ATP Binding Cassette Transporter 1|oxidized low density lipoprotein|Low-Density Lipoprotein 1|*THP-1 Cell|*Autophagy|Atherosclerosis|Signal Transduction|TOR Serine-Threonine Kinases|Cholesterol|Macrophages|TYRP1 protein, human|*Membrane Glycoproteins|AMP-Activated Protein Kinases 38 C1QTNF9B 29953821 Appl Physiol Nutr Metab 2018 10.1139/apnm-2018-0355 3 2 0 1 Humans|Male|Young Adult|Adult|*Complement C1q|*Exercise|High-Intensity Interval Training|Insulin Sensitivity|Adiponectin|Body Mass Index|Adipokines|Muscle, Skeletal 38 C1QTNF9B 29704818 Cytokine 2018 10.1016/j.cyto.2018.04.019 0 0 0 1 *Non-alcoholic Fatty Liver Disease|*Complement C1q|Cross-Sectional Studies|Insulin Resistance|Adipokine|TNF protein, human|*Tumor Necrosis Factor-alpha|Adiponectin|Waist Circumference|TYRP1 protein, human|*Membrane Glycoproteins|Blood Glucose|Body Mass Index|Diabetes Mellitus, Type 2 38 C1QTNF9B 29543038 Diab Vasc Dis Res 2018 10.1177/1479164118763254 0 0 0 1 Humans|*Peripheral Arterial Disease|*Diabetes Mellitus, Type 2|*Complement C1q|*Factor 9|*Lower Extremity|Diabetic Angiopathies|Atherosclerosis|Risk Factors|Tumor Necrosis Factors 38 C1QTNF9B 29381773 PLoS ONE 2018 PMC5790264 10.1371/journal.pone.0192159 5 9 0 1 Humans|*Diabetes Mellitus, Type 2|*Coronary Artery Disease|Adiponectin|TNF protein, human|*Tumor Necrosis Factor-alpha|*Biomarkers|Insulin Resistance|Glycoproteins|*Cell Adhesion Molecules|Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 38 C2CD4B 30586737 Circulation 2018 PMC6438386 10.1161/CIRCULATIONAHA.118.034532 6 5 0 16 *von Willebrand Factor|F8 protein, human|*Factor VIII|*Genome-Wide Association Study|*Blood Coagulation Tests|Venous Thrombosis|Blood Coagulation|*Plasma|Case-Control Studies|Polymorphism, Single Nucleotide|Phenotype|Risk Factors 24 C2CD4B 29625024 Am. J. Hum. Genet. 2018 PMC5985342 10.1016/j.ajhg.2018.02.020 8 0 0 16 Humans|Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Insulin-Secreting Cells|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Alleles|Insulin|Enhancer Elements, Genetic|Proinsulin|Chromosome Mapping 24 C2CD4B 29543849 PLoS ONE 2018 PMC5854349 10.1371/journal.pone.0193882 0 5 0 16 Mice|Animals|*Insulin-Secreting Cells|*Insulin|*Secretory Vesicles|Insulin Secretion|*Insulin, Regular, Human|Exocytosis|Proinsulin|Glucagon|Pancreatic Islets|Glucose 24 C5orf42 29961766 Genet. Med. 2018 10.1038/s41436-018-0082-9 1 0 0 15 *Exome|Genes, Recessive|Whole Exome Sequencing|*Family|Pedigree|Sequence Analysis, DNA|Genetic Predisposition to Disease|Mutation 24 C5orf42 29955609 Biomed Res Int 2018 PMC6000882 10.1155/2018/7202168 2 0 0 15 Pregnancy|Female|Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Genetic Testing|*Prenatal Diagnosis|*Fetus|Mutation|Membrane Proteins 24 C5orf42 29605658 Eur J Med Genet 2018 10.1016/j.ejmg.2018.03.012 1 0 0 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|*Ciliopathy|Cerebellar Diseases|Polydactyly preaxial type 1|Polydactyly|Phenotype|Hypothalamic hamartomas|Hypothalamic Diseases|Nervous System Malformations|Whole Exome Sequencing|Mutations 24 C5orf42 29321670 Eur. J. Hum. Genet. 2018 PMC5839020 10.1038/s41431-017-0019-9 1 1 0 15 Chick Embryo|Humans|Animals|*Hedgehog Proteins|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|*Ciliopathies|Eye Abnormalities|Abnormalities, Multiple|Cerebellum|Retina|Exome|*Signal Transduction|Cilia|Craniofacial Abnormalities|Membrane Proteins|Mutation|Acrocallosal Syndrome|KIF7 protein, human|Kinesin|C5orf42 protein, human 24 CALB2 30583828 Rev Esp Patol 2018 10.1016/j.patol.2018.04.002 0 0 0 555 *Immunohistochemistry|Colombia|PAX8 Transcription Factor|Biomarkers, Tumor|*Tertiary Hospital 1236 CALB2 30583826 Rev Esp Patol 2018 10.1016/j.patol.2018.05.004 0 0 0 555 *Granular Cell Tumor|*Immunohistochemistry|Antigens, Differentiation, Myelomonocytic|Antigens, CD|S100 Proteins|Calbindin 2|Biomarkers, Tumor|Inhibins 1236 CALB2 30555628 Oncotarget 2018 PMC6284738 10.18632/oncotarget.26332 5 2 0 555 Humans|CALB2 protein, human|*Calbindin 2|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|*Signal Transduction|Cell Proliferation|Cell Movement|Focal Adhesion Kinase 1|Cell Survival|Cell Cycle|Epithelial-Mesenchymal Transition|Cell Line, Tumor 1236 CALB2 30553791 Neuroscience 2018 PMC6347472 10.1016/j.neuroscience.2018.12.009 5 0 0 555 Mice|Animals|CALB2 protein, human|*Calbindin 2|*Horn, Dorsal|*Interneuron|Gastrin Releasing Peptide|Posterior Horn Cells|Neuropeptides|Neurokinin B|Substance P|Neurotensin|Dynorphin|Neurons 1236 CALHM1 29768036 Am. 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Physiol. 2018 PMC6172629 10.1152/ajpregu.00015.2018 1 0 0 64 Mice|Animals|*Mice, Knockout|Taste|Taste Buds|*CD36 Antigens|Taste Perception|Food Preferences|Dietary Fat|Eating|soybean oil, phospholipid emulsion|Soy Bean Oil|Mice, Inbred C57BL|Fatty Acids|Phospholipids|CALHM1 protein, mouse|Calcium Channels 84 CALHM1 29739879 Sci Signal 2018 PMC5966022 10.1126/scisignal.aao1815 9 1 0 64 *Synaptic Vesicles|*Neurotransmission|Taste Buds|*Synapses|*Signal Transduction|Calcium Channels|Taste|Ion Channel Gating|Adenosine Triphosphate 84 CALHM1 29681531 Neuron 2018 PMC5934295 10.1016/j.neuron.2018.03.043 14 5 0 64 *Taste|Taste Buds|*Neurotransmission|Calcium Channels|Ion Channel Gating|Taste Perception|Action Potentials|Adenosine Triphosphate|G-Protein-Coupled Receptors 84 CALHM1 29534490 Int J Mol Sci 2018 PMC5877669 10.3390/ijms19030808 20 37 0 64 *Adenosine Triphosphate|Connexins|Calcium Channels|Neurotransmission|Taste Buds|Signal Transduction|Membrane Glycoproteins|Anions 84 CAMK1D 30088950 Syst Biol Reprod Med 2018 10.1080/19396368.2018.1504347 2 0 0 112 Pregnancy|Humans|Female|Fertilization in Vitro|Ovulation Induction|Pregnancy Rate|Follicle Stimulating Hormone|Ovarian Hyperstimulation Syndrome|Sperm Injections, Intracytoplasmic|Anti-Mullerian Hormone|*Assisted Reproductive Technology|Ovarian Follicle|*Prognosis|Gonadotropin-Releasing Hormone|Pregnancy Outcome|Ovary|Pregnancy, Multiple|Treatment Outcome 60 CAMK1D 30054458 Nat Commun 2018 PMC6063971 10.1038/s41467-018-04951-w 43 12 0 112 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Epigenesis, Genetic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Epigenomic|DNA Methylation 60 CAMK1D 30034349 Front Psychiatry 2018 PMC6043864 10.3389/fpsyt.2018.00290 18 3 0 112 Humans|*Depressive Disorder, Major|Genome-Wide Association Study|*Deep Learning|*Antidepressive Agents|Selective Serotonin Reuptake Inhibitors|Psychiatric Status Rating Scales|Treatment Outcome|*Genetic Markers|Single Nucleotide Polymorphisms|Cohort Studies 60 CAMK1D 29533498 Am. J. Reprod. Immunol. 2018 10.1111/aji.12845 3 3 0 112 Female|Pregnancy|Humans|eukaryotic translation initiation factor 5A|*Peptide Initiation Factors|*RNA-Binding Proteins|Apoptosis|Cell Proliferation|RNA, Small Interfering|Cell Line, Tumor|Trophoblast 60 CAMK1D 29470286 J. Pediatr. Gastroenterol. Nutr. 2018 PMC5916321 10.1097/MPG.0000000000001926 1 1 0 112 Child|Male|Humans|*Non-alcoholic Fatty Liver Disease|*Insulin Resistance|*Hispanic|Adiposity|Pediatric Obesity|Body Mass Index|Liver|*Boys|Polymorphism, Single Nucleotide|Risk Factors 60 CAMK2N1 30205384 Cell. Physiol. Biochem. 2018 10.1159/000493411 7 6 0 115 *Carcinoma, Squamous Cell|*Mouth Neoplasms|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|RNA Interference|Cell Movement|Apoptosis|*Proteins|Signal Transduction 60 CAMK2N1 30106247 Brain Behav 2018 PMC5991579 10.1002/brb3.989 1 2 0 115 Animals|Mice|*Ethanol|*Hypnotic Effects|*miRNA|Reflex, Righting|Alcohol Use Disorders|Reflex 60 CAMK2N1 29485117 J. Biosci. 2018 4 0 0 115 Rats|Animals|*Pharmacogenetics|*Cortex, Prefrontal|clozapine N-oxide|Clozapine|*Neurons|*Anxiety|Antipsychotic Agents|*Pharmacogenomic Testing|Proto-Oncogene Proteins c-fos|Maze Test|Calcium-Calmodulin-Dependent Protein Kinase Type 2 60 CAMK2N1 29342962 Int J Mol Sci 2018 PMC5796200 10.3390/ijms19010253 1 11 0 115 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|Core Binding Factor Alpha 3 Subunit|DNA Methylation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|Down-Regulation|Apoptosis|RNA, Messenger|Runx3 protein, human 60 CARD6 29958938 J. Hepatol. 2018 10.1016/j.jhep.2018.06.014 5 7 0 74 Mice|Humans|Animals|*Caspase Activation and Recruitment Domain|*Ischemia-Reperfusion Injury|*Liver|Hepatocytes|*Protective Agents|p38 Mitogen-Activated Protein Kinases|Signal Transduction|Apoptosis|Disease Models, Animal|Inflammation 30 CARD6 29764119 Cancer Res Treat 2018 PMC6333986 10.4143/crt.2018.157 0 0 0 74 Humans|*Whole Exome Sequencing|Poland|*Incidence|*Melanoma|Exome|Mutations, Germline|Genetic Predisposition to Disease|Pedigree|Mutation 30 CARD6 29729191 Hepatology 2018 10.1002/hep.30075 4 3 0 74 Mice|Humans|Animals|*Insulin Resistance|MAP3K5 protein, human|*MAP Kinase Kinase Kinase 5|*Caspase Activation and Recruitment Domain|Nonalcoholic Fatty Liver Disease|Diet, High-Fat|Liver|TYRP1 protein, human|*Membrane Glycoproteins|*Protective Agents|Mice, Obese|Signal Transduction|Mice, Inbred C57BL|Casp6 protein, mouse|Caspase 6|Hepatocyte|Downregulation 30 CARTPT 30343334 Brain Struct Funct 2018 PMC6369013 10.1007/s00429-018-1778-y 2 1 0 1118 Rats|Mice|Animals|*Aldosterone|*Neurons|Solitary Nucleus|NR3C2 protein, human|Mineralocorticoid Receptor|Locus Coeruleus|11-beta-Hydroxysteroid Dehydrogenase Type 2|Axons|Neural Pathways|Sodium, Dietary|Vesicular Glutamate Transporter 2|Amygdala|cocaine- and amphetamine-regulated transcript protein|Nerve Tissue Proteins|Sodium|Rats, Sprague-Dawley|2,5-dichloro-4-bromophenol|*Chlorophenols 39 CARTPT 29726090 BJU Int. 2018 10.1111/bju.14372 1 0 0 1118 Humans|Male|Testicular Germ Cell Tumor|*Prognosis|*Transcriptome|Neoplasm Recurrence, Local|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Seminoma|Orchiectomy|Biomarkers, Tumor|*Relapse 39 CASP5 30558537 BMC Genomics 2018 PMC6296094 10.1186/s12864-018-5304-7 0 0 0 94 *Arachis|*Cadmium|*Plant Roots|*Transcriptome|Gene Expression Regulation, Plant|Sequencing, RNA|Soil Pollutants|*Fabaceae|Biological Transport|Base Sequence|cDNA Libraries|Gene Expression Profiling 152 CASP5 30250284 Cell Death Dis 2018 PMC6155357 10.1038/s41419-018-1023-x 0 4 0 94 Humans|Mice|Animals|*Pyroptosis|CASP5 protein, human|*Caspases|CASP4 protein, human|Caspases, Initiator|*Acute Kidney Injury|Programmed Cell Death|Interleukin-1beta|Necrosis|Apoptosis Regulatory Proteins|Intracellular Signaling Peptides and Proteins|Inflammation|Cell Line|Epithelial Cell|GSDMD protein, human|Neoplasm Proteins 152 CASP5 30003588 Immunol. Cell Biol. 2018 10.1111/imcb.12190 0 2 0 94 Mice|Animals|Humans|*Inflammasomes|*Pseudomonas aeruginosa|*Monocytes|Pseudomonas Infections|Caspase 1|caspase 11, human|*Caspases|Macrophages|Lipopolysaccharides|Interleukin-1beta|Interleukin-18|THP-1 Cells|Inflammation|Apoptosis Regulatory Proteins|Calcium-Binding Proteins|CASP4 protein, human|Caspases, Initiator 152 CASP5 29974533 Photodermatol Photoimmunol Photomed 2018 10.1111/phpp.12411 0 0 0 94 *Propionibacterium acnes|*Staphylococcus epidermidis|*Melanocytes|*DNA Damage|*Skin|*Apoptosis|Ultraviolet Rays 152 CASP5 29715460 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.04.217 3 1 0 94 Humans|*Glioblastoma|*RNA, Long Noncoding|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Cell Proliferation|MicroRNAs|Cell Movement|Up-Regulation|Cell Line, Tumor|Apoptosis|Xenograft Model Antitumor Assays|*Caspases|*Phenotypes|CASP5 protein, human 152 CASZ1 30563911 Genome Res. 2018 PMC6314162 10.1101/gr.241141.118 18 0 0 1001 Humans|*Human Papilloma Virus|*Papillomavirus Infections|*Oral Cancers|Squamous Cell Carcinomas|*Mutations|DNA, Viral 61 CASZ1 30355852 J Biomed Res 2018 PMC6283827 10.7555/JBR.32.20170065 3 0 0 1001 Humans|*Esophageal Cancer|*DNA Methylation|Esophageal Squamous Cell Carcinoma|CpG Islands|Carcinoma, Squamous Cell|H-cadherin|*Cadherins|Promoter Regions, Genetic|*Biomarkers|Gene Expression Regulation, Neoplastic|DNA|China|ING2 protein, human|Receptors, Cytoplasmic and Nuclear|Homeodomain Proteins|Tumor Suppressor Proteins|CASZ1 protein, human|DNA-Binding Proteins 61 CASZ1 30072429 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6112687 10.1073/pnas.1803069115 4 22 0 1001 Mice|Animals|Euchromatin|Heterochromatin|Cell Nucleus|Nuclear Envelope|Lamin A-C|Retinal Rod Photoreceptor Cells|Transcription Factor|lamin B receptor|Receptors, Cytoplasmic and Nuclear|Gene Expression Regulation|RNA Splicing|Cell Differentiation|CASZ1 protein, mouse|DNA-Binding Proteins 61 CASZ1 29660117 Clin. Genet. 2018 10.1111/cge.13362 3 0 0 1001 Humans|Genome-Wide Association Study|Genetic Susceptibility|*Varicose Veins|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|Cohort Studies|*Inflammation|Risk Factors|Russia 61 CASZ1 29506567 J. Exp. Clin. Cancer Res. 2018 PMC5836448 10.1186/s13046-018-0720-8 7 44 0 1001 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Down-Regulation|Prognosis|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Biomarkers, Tumor|Neoplasm Staging|Cell Movement|Neoplasm Grading|Immunohistochemistry|Apoptosis|Kaplan-Meier Estimate|Zinc Fingers 61 CASZ1 29504607 Exp. Mol. Med. 2018 PMC5903826 10.1038/emm.2017.278 2 6 0 1001 *RNA, Long Noncoding|*Cell Differentiation|Cell Proliferation|Signal Transduction|Myocytes, Cardiac|Apoptosis|Cell Line|RNA, Small Interfering|Transforming Growth Factor beta 61 CASZ1 29467767 Front Immunol 2018 PMC5808336 10.3389/fimmu.2018.00184 4 44 0 1001 Animals|*Transcription Factors|*Inflammation|Th17 Cells|Th1 Cells|*Lymphocyte Activation|CD4-Positive T-Lymphocytes|Encephalomyelitis, Autoimmune, Experimental|*Hematopoiesis|Cell Differentiation|Interleukin-17|Cytokines 61 CCBE1 30555263 Cancer Manag Res 2018 PMC6280897 10.2147/CMAR.S181770 2 0 0 132 Humans|*Colorectal Cancer|Prognosis|Kaplan-Meier Estimate|Biomarkers, Tumor|Immunohistochemistry|Neoplasm Staging|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Up-Regulation|*Colonic Neoplasms|Real-Time Polymerase Chain Reaction|Blotting, Western|CCBE1 protein, human|Calcium-Binding Proteins|Tumor Suppressor Proteins 69 CCBE1 30450763 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40633 2 5 0 132 Hennekam lymphangiectasia lymphedema syndrome|Vascular Endothelial Growth Factor C|*Lymphangiectasis, Intestinal|*Craniofacial Abnormalities|*Lymphedema|*Mutation|Phenotype|Homozygote|Lymphatic Vessels|Genotype|Alleles|Calcium-Binding Proteins|Tumor Suppressor Proteins 69 CCBE1 30281646 PLoS ONE 2018 PMC6169972 10.1371/journal.pone.0205108 0 9 0 132 Mice|Animals|*Mouse Embryonic Stem Cells|*Myocytes, Cardiac|*Cell Differentiation|LIM-Homeodomain Proteins|Embryonic Stem Cells|*Organogenesis|Cell Lineage|Homeobox Protein Nkx-2.5|Mesoderm|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|*Collagen Type I|Ccbe1 protein, mouse|Calcium-Binding Proteins|Tumor Suppressor Proteins 69 CCBE1 30204931 Dev. Dyn. 2018 10.1002/dvdy.24670 2 0 0 132 Humans|Mice|Animals|*Coronary Vessels|VEGF-C|Lymphangiogenesis|Vascular Endothelial Growth Factor Receptor-3|Lymphatic Vessels|*Organogenesis|Signal Transduction|Heart|Calcium-Binding Proteins|Tumor Suppressor Proteins|HEK293 Cells|CCBE1 protein, human|Ccbe1 protein, mouse 69 CCBE1 30165116 J. Biotechnol. 2018 10.1016/j.jbiotec.2018.08.015 0 0 0 132 Humans|*Glycosylation|Proteomics|Lymphatic Vessels|Vascular Endothelial Growth Factor C|Tumor Suppressor Proteins|*Collagen Type I|Calcium-Binding Proteins|Transfection|CCBE1 protein, human 69 CCBE1 29842991 Ann. Anat. 2018 10.1016/j.aanat.2018.05.003 5 0 0 132 Vascular Endothelial Growth Factor C|Endothelial Cells|Vascular Endothelial Growth Factor A|FLT4 protein, human|Vascular Endothelial Growth Factor Receptor-3|Lymphangiogenesis|Lymphatic Vessels|Tumor Suppressor Proteins|Homeodomain Proteins|Signal Transduction|Cell Differentiation|Endothelium, Vascular|Proteolysis 69 CCBE1 29773646 Development 2018 PMC6001371 10.1242/dev.160184 6 1 0 132 Mice|Animals|*Lymphatic Vessels|Lymphangiogenesis|*Progenitor Cells|*Veins|Vascular Endothelial Growth Factor Receptor-3|Homeodomain Proteins|*Embryonic Development|Tumor Suppressor Proteins|Cell Differentiation|Transcription Factors|Gene Expression Regulation, Developmental|Endothelial Progenitor Cells|*Cardiovascular System 69 CCDC170 30382883 Genome Med 2018 PMC6208125 10.1186/s13073-018-0590-x 7 0 0 50 22 CCDC170 30149579 Int J Mol Sci 2018 PMC6163198 10.3390/ijms19092512 3 0 0 50 22 CCDC170 29855537 Sci Rep 2018 PMC5981393 10.1038/s41598-018-25065-9 2 8 0 50 22 CCDC170 29436103 Genes Chromosomes Cancer 2018 10.1002/gcc.22533 5 0 0 50 22 CCDC88A 30576236 Am. J. Physiol., Cell Physiol. 2018 10.1152/ajpcell.00262.2018 6 1 0 649 Humans|Mice|Animals|*RNA, Long Noncoding|*Down-Regulation|MicroRNAs|Human Umbilical Vein Endothelial Cells|Cell Proliferation|Upregulation|Signal Transduction|MIRN128 microRNA, human|girdin protein, mouse|Microfilament Proteins|Vesicular Transport Proteins 131 CCDC88A 30536309 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201811_16384 2 6 0 649 Humans|Child|*Wilms Tumor|Cell Proliferation|MicroRNAs|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|*Neoplastic Processes|Apoptosis|Kidney Neoplasms|MIRN144 microRNA, human 131 CCDC88A 30500482 iScience 2018 PMC6263091 10.1016/j.isci.2018.11.022 3 1 0 649 Humans|Signal Transduction|Microfilament Proteins|Cell Migration|Phosphorylation|Vesicular Transport Proteins|Phosphatidylinositol 3-Kinases|Actin|*B-Lymphocytes|Protein Binding|Cell Line, Tumor|HeLa Cells|CCDC88A protein, human 131 CCDC88A 30401563 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.10.163 1 0 0 649 Humans|*Periodontal Ligament|F-Actin|Microfilament Proteins|Actin Filament|STAT3 protein, human|STAT3 Transcription Factor|Proto-Oncogene Proteins c-akt|Cell Movement|Vesicular Transport Proteins|Upregulation|Cell Proliferation|Phosphorylation 131 CCDC88A 30392057 Neurol. Sci. 2018 10.1007/s10072-018-3626-5 1 0 0 649 Child|Humans|PEHO syndrome|*Hypsarrhythmia|*Codon, Nonsense|Saudi Arabia|*Optic Atrophy|Brain Edema|Neurodegenerative Diseases|*Syndrome|*Brain Diseases|*Edema|*Homozygote|Epilepsy|Phenotype|Mutation|Cerebellum|CCDC88A protein, human|Microfilament Proteins|Vesicular Transport Proteins 131 CCDC88A 30358104 Mol Oncol 2018 PMC6360365 10.1002/1878-0261.12398 7 8 0 649 Humans|Early Detection of Cancer|*Pancreatic Cancer|CA-19-9 Antigen|Carcinoma, Pancreatic Ductal|Biomarkers, Tumor|AUC|Receiver Operating Characteristic|Prognosis|MicroRNAs|Pancreas|Exosomes|Messenger RNA|Case-Control Studies|CCDC88A protein, human|Microfilament Proteins|Vesicular Transport Proteins 131 CCDC88A 30194792 Cancer Sci. 2018 PMC6215880 10.1111/cas.13795 3 3 0 649 Humans|*Cell Adhesion|*Cell Migration|Microfilament Proteins|CDH1 protein, human|E Cadherin|Vesicular Transport Proteins|Actin|Actin Cytoskeleton|Signal Transduction|Cytoskeleton|Antigens, CD|Cell Line, Tumor|Collagen|Fibroblast 131 CCDC88A 30145643 Mol. Cell. Biochem. 2018 PMC6382572 10.1007/s11010-018-3433-6 1 0 0 649 Humans|*Endoplasmic Reticulum Stress|*Cell Survival|Signal Transduction|Unfolded Protein Response|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Transcription Factor CHOP|Vesicular Transport Proteins|Microfilament Proteins|Programmed Cell Death|Phosphorylation|HeLa Cells|Transcription Factor|G Protein|Upregulation 131 CCDC88A 30094535 J. Cancer Res. Clin. Oncol. 2018 10.1007/s00432-018-2710-9 6 2 0 649 Humans|Female|*Cytoskeletal Proteins|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Prognosis|Gene Expression Regulation, Neoplastic|Cytoskeleton|Microtubules|Cell Line, Tumor|RNA Interference|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate|Disease Progression|Cell Proliferation 131 CCDC88A 29991479 Dis Model Mech 2018 PMC6078409 10.1242/dmm.033092 3 15 0 649 Adult|Humans|Pregnancy|Female|Sheep|Animals|*Cartilage, Articular|*Proteomics|*Fibrocartilage|Cartilage Diseases|Chondrocytes|Osteoarthritis|Chondrogenesis|Regeneration|*Fetal Tissue|Calgranulin A|Calgranulin B|Proteins|*Prenatal Care|CCDC88A protein, human|Microfilament Proteins|Vesicular Transport Proteins 131 CCDC88A 29989653 Oncol. Rep. 2018 10.3892/or.2018.6511 1 7 0 649 Mice|Animals|Mice, Nude|*Colorectal Carcinoma|Cell Proliferation|shRNA|Cell Movement|Carcinoma, Hepatocellular|Liver Neoplasms|Gene Expression Regulation, Neoplastic|Microfilament Proteins|Proto-Oncogene Proteins c-akt|STAT3 protein, human|STAT3 Transcription Factor|Cell Line, Tumor|Vesicular Transport Proteins|Downregulation|Signal Transduction|Transfection|RNA, Messenger 131 CCDC88A 29901184 Oncol. Rep. 2018 PMC6072288 10.3892/or.2018.6469 4 34 0 649 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Signal Transduction|*Apoptosis|Cell Proliferation|*Pancreatic Cancer|Cell Movement|Microfilament Proteins|Vesicular Transport Proteins|RNA, Small Interfering|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Phosphorylation|*Pancreas 131 CCDC88A 29786109 Int. J. Mol. Med. 2018 10.3892/ijmm.2018.3685 0 5 0 649 Humans|*Phosphorylation|*Endothelial Cell|*Blood Platelets|Cell Movement|Microfilament Proteins|Vesicular Transport Proteins|Proto-Oncogene Proteins c-akt|Neovascularization, Pathologic|Cell Proliferation|*Cell Senescence|Apoptosis|RNA, Small Interfering|Viability, Cell|*Aging 131 CCL14 30028015 Eur. J. Immunol. 2018 10.1002/eji.201747452 0 2 0 47 *Kallikrein B'|*Chemokines, CC|Macrophage Inflammatory Proteins|Chemokines|Receptors, Chemokine|Inflammation 77 CCL14 29703961 J. Hum. Genet. 2018 10.1038/s10038-018-0452-9 0 0 0 47 Humans|*Hepacivirus|Hepatitis C, Chronic|Hepatitis C|SNPs|Genotype|Alleles|Asian Continental Ancestry Group|Antiviral Agents|Genetic Predisposition to Disease|*Chemokines, CC|Case-Control Studies 77 CCL15 30377568 Oncoimmunology 2018 PMC6205014 10.1080/2162402X.2018.1504729 3 2 0 148 Humans|*Coculture Techniques|*Mast Cells|*Colon Cancer|Colorectal Cancer|Tumor Microenvironment|*B Cells|Gene Expression Regulation, Neoplastic|Cell Proliferation 118 CCL15 30181917 Immune Netw 2018 PMC6117514 10.4110/in.2018.18.e29 7 6 0 148 Humans|Female|Cystadenocarcinoma, Serous|Ovarian Cancer|Carcinoma, Ovarian Epithelial|*Chemokines|Tumor Suppressor Protein p53|Mutation 118 CCL15 30132835 Int. J. Cancer 2018 PMC6235711 10.1002/ijc.31821 2 0 0 148 Humans|*Prospective Studies|*Cohort Studies|Japan|*Colorectal Cancer|Biomarkers, Tumor|Chemokines|Inflammation|Risk Factors|C-Reactive Protein|Case-Control Studies|Cytokines|*Colonic Neoplasms|Logistic Models|Cox Proportional Hazards Models|Colon|Intercellular Signaling Peptides and Proteins 118 CCL15 30070719 Hepatology 2018 10.1002/hep.30134 18 0 0 148 Humans|*Carcinoma, Hepatocellular|*Monocytes|*Liver Neoplasms|CCL15 protein, human|*Macrophage Inflammatory Proteins|*Chemokines, CC|Receptors, CCR1|*Disease Progression|Chemokines|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Myeloid Cells|Cell Movement|Tumor Microenvironment 118 CCL15 30028015 Eur. J. Immunol. 2018 10.1002/eji.201747452 0 2 0 148 *Kallikrein B'|*Chemokines, CC|Macrophage Inflammatory Proteins|Chemokines|Receptors, Chemokine|Inflammation 118 CCL15 29977225 Front Endocrinol (Lausanne) 2018 PMC6021500 10.3389/fendo.2018.00314 19 44 0 148 Humans|CXCL8 protein, human|*Interleukin-8|*Chemokines|*Thyroid Cancer|Thyroid Gland|Chemokine CCL2|Cell Cycle|Inflammation 118 CCL15 29904737 Adv Radiat Oncol 2018 PMC6000081 10.1016/j.adro.2017.12.007 1 0 0 148 Humans|*Carcinoma, Non-Small-Cell Lung|*Tumor Burden|*Lung Cancer|Fluorodeoxyglucose F18|Positron-Emission Tomography|Multimodal Imaging|Radiopharmaceuticals|Tomography, X-Ray Computed|Neoplasm Staging|Chemoradiotherapy|Cytokines 118 cd248 30402111 Stem Cells Int 2018 PMC6192083 10.1155/2018/5868745 1 0 0 366 Humans|Mesenchymal Stromal Cells|Cell Differentiation|antigens, CD200|Antigens, CD|Osteogenesis|CD163 antigen|Chondrogenesis|Cell Separation|Receptors, Cell Surface|Flow Cytometry|Cells, Cultured|Cell Proliferation|Adipogenesis|CD271|Cell Count|CD248 protein, human|Antigens, Neoplasm 114 cd248 30285896 Arthritis Res. Ther. 2018 PMC6235209 10.1186/s13075-018-1719-4 6 2 0 366 Humans|*Myofibroblasts|*Cell Differentiation|*Sclerosis, Systemic|Platelet-Derived Growth Factor BB|Mesenchymal Stem Cells|*Cells, Stromal|Fibrosis|Proto-Oncogene Proteins c-sis|Cells, Cultured|Transforming Growth Factor beta|Cell Proliferation|Actins|Signal Transduction|CD248 protein, human|Antigens, Neoplasm|Antigens, CD 114 cd248 30226075 Cell Transplant 2018 PMC6180722 10.1177/0963689718795096 3 8 0 366 Humans|Mice|Animals|*Liquid Chromatography|*Proteomics|*Tandem Mass Spectrometry|*Mesenchymal Stem Cells|Proteome|Adipose Tissue|Cell Differentiation|Cells, Cultured|POSTN protein, human|Cell Adhesion Molecules|PTK7 protein, human|Receptor Protein-Tyrosine Kinases|CD109 protein, human|Neoplasm Proteins|Antigens, CD|GPI-Linked Proteins|ADAM9 protein, human|Membrane Proteins 114 cd248 29984199 J Transl Int Med 2018 PMC6032187 10.2478/jtim-2018-0018 1 2 0 366 Animals|*Budd-Chiari Syndrome|*Fibrosis, Liver|Hepatic Stellate Cell|CD248 protein, human|*Antigens, Neoplasm|*Antigens, CD|Cell Hypoxia|Signal Transduction|Basic Helix-Loop-Helix Transcription Factors|Kupffer Cells|Hypoxia 114 cd248 29304474 Eur. J. Cancer 2018 10.1016/j.ejca.2017.10.035 6 0 0 366 Humans|Animals|Mice|CD248 protein, human|*Antigens, Neoplasm|*Antigens, CD|*Sarcoma|Immunotoxins|Ribosome Inactivating Proteins, Type 1|Single-Chain Variable Fragment|Mice, Nude|Cell Line, Tumor|Xenograft Model Antitumor Assays|*Soft Tissue Neoplasms 114 CD5L 30487357 Exp. Anim. 2018 PMC6511520 10.1538/expanim.18-0108 0 0 0 193 Mice|Animals|*Non-alcoholic Fatty Liver Disease|Carcinoma, Hepatocellular|Liver Neoplasms|*Disease Models, Animal|Liver|Diet, High-Fat|*Trans Fatty Acids|Mice, Inbred C57BL|*Hypercholesterolemia|Fructose|Obesity|*Hyperlipidemias|Cholesterol 98 CD5L 30326743 Am. J. Respir. Cell Mol. Biol. 2018 10.1165/rcmb.2018-0272OC 2 1 0 193 Animals|*Macrophage|*Sepsis|IL10 protein, human|IL10|Cytokines|*Apoptosis Regulatory Proteins|Chemokines|Inflammation|Neutrophils|Disease Models, Animal|Apoptosis 98 CD5L 30324136 Sci Adv 2018 PMC6179379 10.1126/sciadv.aau1199 6 10 0 193 polymeric IgM|*Immunoglobulin M|Immunoglobulin J-Chains|Immunoglobulin Fc Fragments|Apoptosis Regulatory Proteins|*Cell Membrane|Macrophage 98 CDC42EP4 30394597 Glia 2018 10.1002/glia.23524 0 1 0 127 Animals|Rats|Excitatory Amino Acid Transporter 2|Glutamate|Astrocytes|Excitatory Amino Acid Transporter 1|Neuroglia|Neurons|Biological Transport|Cells, Cultured|Cytoskeleton|Cell Membrane|Biotinylation|Blotting, Western|Transfection 20 CDC42EP4 29330091 Neurochem. Int. 2018 10.1016/j.neuint.2018.01.003 0 3 0 127 *Synapses|*Astroglias|Purkinje Cells|Glutamate Transporter|Synaptic Transmission|Glutamate|Neuroglia|Excitatory Amino Acid Transporter 1|Excitatory Postsynaptic Potentials|Cerebellum|Presynaptic Terminals|Patch-Clamp Techniques 20 CDCA7 30307408 J. Clin. Invest. 2018 PMC6307953 10.1172/JCI99751 7 1 0 92 Humans|HEK293 Cells|CDCA7 protein, human|*Nuclear Proteins|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|*Centromeres|*Mutations|Immunologic Deficiency Syndromes|DNA Helicases|DNA Methylation|Immunodeficiency syndrome, variable|Primary Immunodeficiency Diseases|*DNA End-Joining Repair|*Genes, cdc|Repressor Proteins|Face|Zinc Finger|HELLS protein, human 50 CDCA7 30207007 J. Mol. Recognit. 2018 10.1002/jmr.2763 1 3 0 92 Humans|*RNA, Long Noncoding|*Human Embryonic Stem Cells|Gene Regulatory Networks|Sequence Analysis, RNA|Gene Expression Profiling|RNA, Messenger|MicroRNAs|Transcriptome|Computational Biology|Genes, cdc|Cell Cycle 50 CDCA7 30151890 Int. J. Cancer 2018 10.1002/ijc.31766 7 2 0 92 Humans|*Triple-Negative Breast Cancer|Neoplasm Recurrence, Local|CDCA7 protein, human|*Nuclear Proteins|Cell Proliferation|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Division Cycle, Cell|*Genes, cdc|MicroRNAs|Upregulation|Cell Movement|Promoter Regions, Genetic|Prognosis|EZH2 protein, human|Enhancer of Zeste Homolog 2 Protein 50 CDCA7 30085123 Nucleic Acids Res. 2018 PMC6212772 10.1093/nar/gky682 8 38 0 92 *DNA Methylation|DNA methyltransferase 3B|*DNA (Cytosine-5-)-Methyltransferases|CDCA7 protein, human|Nuclear Proteins|Repressor Proteins|Zinc Finger|Immunologic Deficiency Syndromes|Transcription Factors|DNA Helicases|Centromere|Promoter Regions, Genetic|Immunodeficiency syndrome, variable|Primary Immunodeficiency Diseases|Epigenetic|Mutation|Activation, Transcriptional|Face 50 CDH19 30219970 Virchows Arch. 2018 PMC6267237 10.1007/s00428-018-2450-x 4 0 0 36 *DNA Copy Number Variations|Retrospective Studies|*Neuroendocrine Tumors|Intestinal Neoplasms|*Intestine, Small|*Mutations|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|Gene Expression Profiling|Biomarkers, Tumor|Cluster Analysis|Chromosome Mapping|Genes, cdc 25 CDH19 30094464 Pediatr. Surg. Int. 2018 10.1007/s00383-018-4331-4 2 0 0 36 *Gastroschisis|Abnormalities, Multiple|Chromosome Aberrations|Syndromes 25 CDH19 29520852 Glia 2018 10.1002/glia.23320 4 0 0 36 Rats|Animals|Satellite Cells, Perineuronal|*Cells, Glial|Schwann Cells|Ganglia, Spinal|Sciatic Nerve|Axons|Neurons|Coculture|DCHS1 protein, human|Cadherins|*B Cells|Cells, Cultured|Cell Differentiation 25 CDH22 30439624 Biosens Bioelectron 2018 10.1016/j.bios.2018.10.051 0 0 0 30 Humans|poly(phosphazene)|benzaldehyde|*Benzaldehydes|Reproducibility of Results|*Biosensors|*Electrode|*Polymer|*Organophosphorus Compounds|Antibodies, Immobilized|Electrochemical Techniques|Immunoassay|Limit of Detection|Biomarkers, Tumor|Raman Spectroscopy|CDH22 protein, human|Cadherins 26 CDH22 29850476 Int J Genomics 2018 PMC5903198 10.1155/2018/8076397 1 11 0 30 *Metabolic Syndrome|*Epigenome|CpG Islands|DNA Methylation|*Schizophrenia|Epigenesis, Genetic|Antipsychotic Agents|Genome-Wide Association Study 26 CDHR1 30160356 J. Cell. Mol. Med. 2018 PMC6201214 10.1111/jcmm.13841 9 1 0 33 Humans|Mice|Animals|*Retinal Dystrophy|*Homozygote|*Next Generation Sequencing|DNA Mutational Analysis|Genes, Recessive|Electroretinography|*Codon, Nonsense|Mutation|Pedigree|Retina|Phenotypes|*Chinese|Retinal Cone|Tomography, Optical Coherence|Nerve Tissue Proteins|Visual Acuity|CDHR1 protein, human|Cadherins 34 CDHR1 29555955 Sci Rep 2018 PMC5859282 10.1038/s41598-018-22096-0 15 0 0 33 Humans|*Cone-Rod Dystrophies|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|Retinitis Pigmentosa|Electroretinography|DNA Mutational Analysis|Mutations|Sequencing, Next-Generation|Phenotype|Genotype-Phenotype Correlations|Retina|Eye Proteins|Pedigree|Macular Degeneration|Coherence Tomography, Optical|Visual Acuity|NPHP1 protein, human|Membrane Proteins 34 CDK2AP2 30572486 Medicine (Baltimore) 2018 PMC6320171 10.1097/MD.0000000000013666 3 12 0 664 Humans|*Promoter Regions, Genetic|*DNA Methylation|Death-Associated Protein Kinases|Receptors, Retinoic Acid|Tumor Suppressor Proteins|*Disease Progression|*Patient Compliance 32 CDK2AP2 30539751 Urol. Oncol. 2018 10.1016/j.urolonc.2018.05.025 1 0 0 664 Humans|*Urinary Bladder Neoplasms|*Tumor Suppressor Protein p53|Cystectomy|Carcinoma, Transitional Cell|Prognosis|Cyclin-Dependent Kinase Inhibitor p21|Neoplasm Staging|Biomarkers, Tumor|Retinoblastoma Protein|Cyclins|Survival Rate 32 CDK2AP2 30375264 Tumour Biol. 2018 10.1177/1010428318808678 1 2 0 664 Humans|*Tumor Suppressor Protein p14ARF|*Adenocarcinoma|Carcinoma, Signet Ring Cell|Prognosis|Adenocarcinoma, Mucinous|Stomach Neoplasms|Neoplasm Staging|Biomarkers, Tumor|*Intestine, Small|Lymphatic Metastasis|*Duodenal Neoplasms|Survival Rate|*Cyclin-Dependent Kinase Inhibitor p16|USP10 protein, human|Ubiquitin Thiolesterase 32 CDK2AP2 30343278 Cancer Genomics Proteomics 2018 PMC6299786 10.21873/cgp.20103 0 1 0 664 Neoplasm Staging|Gene Expression Regulation, Neoplastic|RNA, Messenger 32 CDK2AP2 30264192 Mol. Genet. Genomics 2018 10.1007/s00438-018-1495-5 0 0 0 664 Humans|centromere protein E|*Chromosomal Proteins, Non-Histone|*Aneuploid Cells|Chromosome Instability|Mad2 Proteins|M Phase Cell Cycle Checkpoints|Chromosome Segregation|Cell Cycle Proteins|Mitosis|HCT116 Cells|Tumor Suppressor Protein p53|RNA Interference|Cell Proliferation|Apoptosis|Protein-Serine-Threonine Kinases|RNA, Small Interfering|Chromosome 32 CDK2AP2 30202240 Cancer Cell Int. 2018 PMC6126007 10.1186/s12935-018-0618-8 1 6 0 664 Humans|*Gene Regulatory Networks|Long Non-Coding RNA|Cell Proliferation|SOXB1 Transcription Factors|Gene Expression Regulation, Neoplastic|Up-Regulation|Cell Line, Tumor 32 CDK2AP2 29865038 Cancer Biomark 2018 10.3233/CBM-171156 1 4 0 664 Carcinoma, Hepatocellular|Liver Neoplasms|*DNA Methylation|CDH1 protein, human|*E Cadherin|*Antigens, CD|Promoter Regions, Genetic|Liver Cirrhosis|Genes, Tumor Suppressor|Hepatitis C 32 CDKL2 30292871 Gene 2018 10.1016/j.gene.2018.10.009 2 1 0 100 *Carcinoma, Hepatocellular|*Liver Neoplasms|CpG Islands|DNA Methylation|Gene Expression Regulation, Neoplastic|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|Promoter Regions, Genetic|Down-Regulation|Cell Line, Tumor|RNA, Messenger|Cyclins 20 CDKL2 29790675 Cancer Med 2018 PMC6051174 10.1002/cam4.1577 3 16 0 100 Humans|*Stomach Neoplasms|*Cell Proliferation|CDKL2 protein, human|Calcium-Calmodulin-Dependent Protein Kinases|*Cyclin-Dependent Kinases|Neoplasm Invasiveness|Prognosis|Cell Movement|Disease-Free Survival|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Biomarkers, Tumor|Proportional Hazards Model|*Cell Cycle|Disease Progression|Immunohistochemistry|Cyclins 20 CDKL2 29420175 Cell Rep 2018 PMC5846859 10.1016/j.celrep.2017.12.083 11 6 0 100 Animals|Humans|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Cilia|Cyclin-Dependent Kinases|Mitogen-Activated Protein Kinases|Signal Transduction|Sensory Receptor Cells|Mutations|CDKL-1 protein, C elegans 20 CDKL2 31938157 Int J Clin Exp Pathol 2018 PMC6958001 1 0 0 100 Humans|*Glioma|Brain Neoplasms|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|*Disease Progression|Prognosis|*Cell Nucleus|Biomarkers, Tumor 20 CDNF 30551485 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.11.028 0 2 0 99 Animals|*Microglia|*Proto-Oncogene Proteins c-akt|*Dopamine|MTOR protein, human|TOR Serine-Threonine Kinases|*Signal Transduction|Phosphatidylinositol 3-Kinases|Forkhead Box Protein O1|Lipopolysaccharides|*Protective Agents|Phosphorylation|Inflammation|Apoptosis 99 CDY1 30388030 Cell Reprogram 2018 10.1089/cell.2018.0035 1 0 0 6 Animals|Humans|Mice|*Induced Pluripotent Stem Cells|*Keratinocytes|Mice, Nude|*Mice, Inbred BALB C|Embryoid Bodies|Cellular Reprogramming|Embryonic Stem Cells|*Epidermis|Octamer Transcription Factor-3|Cell Differentiation|SOXB1 Transcription Factors|Cells, Cultured|Fibroblasts|Teratoma|Kruppel-Like Transcription Factors|Adipocytes 54 CEBPE 30569130 Oncol. Rep. 2018 10.3892/or.2018.6926 1 15 0 172 RUNX1 Translocation Partner 1 Protein|Core Binding Factor Alpha 2 Subunit|Translocation, Genetic|*Signal Transduction|Leukemia, Myeloid, Acute|Oncogene Proteins, Fusion|*Cell Differentiation|Gene Expression Regulation, Leukemic|Cell Proliferation|MAPK1 protein, human|*Mitogen-Activated Protein Kinase 1|Apoptosis|*Pathway, ERK|Genes, cdc|Cell Line, Tumor|Downregulation|CCNE2 protein, human|Cyclins 144 CEBPE 30487223 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6294900 10.1073/pnas.1814397115 15 0 0 172 *Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Oncogene Proteins, Fusion|Sequencing, RNA|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Transcriptome|Genomics|Mutation|B-Lymphocytes 144 CEBPE 30472158 Cell Stem Cell 2018 PMC6602096 10.1016/j.stem.2018.10.016 5 4 0 172 Humans|Mice|Animals|*Cell Self Renewal|*Hematopoiesis|Leukemia, Myeloid, Acute|Gene Expression Regulation, Leukemic|Hematopoietic Stem Cells|Neoplastic Stem Cells|Homeodomain Proteins|Genes, Homeobox|Cell Differentiation|Apoptosis 144 CEBPE 30107053 Clin. Exp. Allergy 2018 PMC6659730 10.1111/cea.13249 4 0 0 172 *Immunoglobulin E|*Asthma|Eosinophils|*Gene Expression|*Networks, Gene 144 CEBPE 29977016 Leukemia 2018 PMC6327050 10.1038/s41375-018-0184-z 3 1 0 172 Child|Humans|*Genetic Predisposition to Disease|Genome-Wide Association Study|*Epsilon-Binding Protein|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Ikaros Transcription Factor|Polymorphism, Single Nucleotide|Allele|*Promoter Regions, Genetic|CCAAT-Enhancer-Binding Proteins|*Burkitt Lymphoma|Translocation, Genetic|*Regulatory Sequences, Nucleic Acid|Case-Control Studies|B-Lymphocytes|CEBPE protein, human 144 CEBPE 29966306 Int J Mol Sci 2018 PMC6073189 10.3390/ijms19071918 7 2 0 172 Humans|VDR protein, human|*Receptors, Calcitriol|*Receptor, Retinoic Acid|*CCAAT Enhancer Binding Protein|*Leukemia, Myeloid, Acute|Tretinoin|Cell Differentiation|Calcitriol|HL-60 Cells|Hematopoiesis|Transcription Factors 144 CEBPE 29773596 Haematologica 2018 PMC6068032 10.3324/haematol.2018.190280 0 9 0 172 Granulocytes|Transcription Factors|CCAAT-Enhancer-Binding Proteins|Leukopoiesis|Cell Differentiation|Myelopoiesis|Gene Expression Regulation|Hematopoiesis|Neutrophils|Cell Line 144 CEBPE 29651288 Front Immunol 2018 PMC5884887 10.3389/fimmu.2018.00588 5 8 0 172 Specific Granule Deficiency|Leukocyte Disorders|CCAAT-Enhancer-Binding Proteins|Cytoplasmic Granules|Neutrophils|Lactoferrin|Mutations|Immunologic Deficiency Syndromes 144 CEBPE 29466759 Immunity 2018 10.1016/j.immuni.2018.02.002 39 0 0 172 Mice|Animals|*Neutrophils|*Bone Marrow|Granulocytes|Cell Differentiation|*Cell Movement|Granulocyte Colony-Stimulating Factor|CCAAT-Enhancer-Binding Proteins|Hematopoiesis|Transcription Factor 144 CEBPE 29335448 Sci Rep 2018 PMC5768812 10.1038/s41598-017-19127-7 3 0 0 172 Child|Humans|Infant, Newborn|Infant|Child, Preschool|Adolescent|Young Adult|Adult|Genome-Wide Association Study|*Genetic Predisposition to Disease|Japan|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Single Nucleotide Polymorphism|Ikaros Transcription Factor|*Genetic Loci|Alleles|Linkage Disequilibrium|Gene Frequency|CCAAT-Enhancer-Binding Proteins|Genotype|Case-Control Studies|Hispanic|Logistic Models|Tokyo|ARID5B protein, human|DNA-Binding Proteins 144 CECR2 30535433 Oncol. Rep. 2018 PMC6313003 10.3892/or.2018.6903 0 1 0 63 Humans|*Glioma|DNA Modification Methylases|*Prognosis|DNA Repair Enzymes|Promoter Regions, Genetic|Brain Neoplasms|Tumor Suppressor Proteins|DNA Methylation|Biomarkers, Tumor|Kaplan-Meier Estimate|Disease-Free Survival|MGMT protein, human|Cecr2 protein, human|Transcription Factors 32 CECR2 30143612 Nat Commun 2018 PMC6109101 10.1038/s41467-018-05451-7 9 9 0 63 Humans|*Neural Tube Defects|Histone|Folic Acid|SMARCA4 protein, human|Nuclear Proteins|*Neurogenesis|Transcription Factors|DNA Helicases|*Gene Expression|Downregulation|Cecr2 protein, human 32 CECR2 29755503 Front Genet 2018 PMC5932955 10.3389/fgene.2018.00128 0 1 0 63 Animals|Female|*Genome-Wide Association Study|*Chickens|*Eggs|Phenotype|Quantitative Trait Loci|Genotype|Breeding|Polymorphism, Single Nucleotide|Breeding, Selective|Genomics 32 CELF2 30508596 Biochim Biophys Acta Gene Regul Mech 2018 10.1016/j.bbagrm.2018.11.006 2 1 0 220 Humans|*Heme Oxygenase-1|*Myoblasts, Cardiac|CELF1 Protein|RNA Binding Protein|*Myoblast|Myocytes, Cardiac|mRNA Stability|Cardiac Hypertrophy|Carbon Monoxide|RNA, Messenger|Sequencing, RNA|Immunoprecipitation|Gene Expression Regulation, Developmental|Downregulation|CELF2 protein, human|CELF Proteins|Nerve Tissue Proteins 85 CELF2 30425495 Neuropsychiatr Dis Treat 2018 PMC6205134 10.2147/NDT.S173632 4 6 0 220 *Ischemia-Reperfusion Injury|*Neurons|*Cell Death|*Protective Agents|miRNAs|Cell Hypoxia|Apoptosis|Glucose|Cell Survival|Oxygen|Cell Proliferation|Cells, Cultured 85 CELF2 30268547 World Neurosurg 2018 10.1016/j.wneu.2018.09.155 4 4 0 220 Humans|Animals|Mice|*Glioma|*Cell Proliferation|*Apoptosis|MicroRNAs|Brain Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Mice, Nude|*Neoplastic Processes 85 CELF2 29981323 Exp. Neurol. 2018 10.1016/j.expneurol.2018.07.003 5 1 0 220 Rats|Animals|*Peripheral Nerve Injuries|*Alternative Splicing|*Nerve Regeneration|*Axons|Nerve, Sciatic|Dorsal Root Ganglion|Sciatic Neuropathy|Neurons|Base Sequence|RNA-Binding Proteins|Downregulation 85 CELF2 29945667 Neural Dev 2018 PMC6020313 10.1186/s13064-018-0112-y 1 19 0 220 Animals|*Zebrafish|*Hindbrain|Zebrafish Proteins|Transcription Factors|Embryo, Nonmammalian|Body Patterning|Homeodomain Proteins|Gene Expression Regulation, Developmental|Fibroblast Growth Factors|Retinoic Acid|Morphogenesis|Nerve Tissue Proteins|In Situ Hybridization|MafB Transcription Factor|Hepatocyte Nuclear Factor 1-beta|Neurons|*Gene Expression|Signal Transduction 85 CELF2 29910823 Front Genet 2018 PMC5992410 10.3389/fgene.2018.00183 3 0 0 220 *Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Gene Expression Profiling|Transcriptome|Prognosis|Gene Expression Regulation, Neoplastic|*Disease Progression 85 CELF2 29501762 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.02.104 9 2 0 220 Humans|*Stomach Neoplasms|*Apoptosis|MicroRNAs|Downregulation|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Up-Regulation|Cell Movement|Cell Line, Tumor|Oncogenesis|*RNA-Binding Proteins|China|CELF2 protein, human|CELF Proteins|Nerve Tissue Proteins|MIRN615 microRNA, human 85 CELF4 30273353 PLoS Comput. Biol. 2018 PMC6181426 10.1371/journal.pcbi.1006506 2 0 0 34 Animals|Mice|*Microelectrodes|*Neurons|Action Potentials|Models, Neurological|Nerve Net|Algorithms|*Record 43 CELF4 29805044 Am. J. Hum. Genet. 2018 PMC5992120 10.1016/j.ajhg.2018.04.005 6 0 0 34 Pregnancy|Humans|Female|*Translocation, Genetic|Karyotyping|Chromosome Aberrations|Prenatal Diagnosis|Amniocentesis|Chromosome Breakpoints|Ultrasonography, Prenatal|Phenotype 43 CELF4 29557343 Circ Genom Precis Med 2018 10.1161/CIRCGEN.117.001753 9 0 0 34 Humans|Genome-Wide Association Study|Anthracyclines|Cardiotoxicity|*Heart Diseases|Antibiotics, Antineoplastic|SNPs|Genetic Predisposition to Disease|Risk Assessment|Risk Factors 43 CELSR2 30473251 Comput Biol Chem 2018 10.1016/j.compbiolchem.2018.11.010 0 0 0 105 *Genome-Wide Association Study|LDL Cholesterol|Cholesterol, HDL|Atherosclerosis|Triglycerides|Polymorphism, Single Nucleotide|*Lifestyle|Cardiovascular Diseases 106 CELSR2 30387901 Genet. Epidemiol. 2018 10.1002/gepi.22169 1 0 0 105 *Multifactor Dimensionality Reduction|*Epistasis, Genetic|*Phenotypes|Traits, Complex|Models, Genetic|Simulations, Computer|Model, Logit|Algorithms|Interactions, Gene-Environment|Polymorphism, Single Nucleotide 106 CELSR2 30312642 Neurotoxicology 2018 10.1016/j.neuro.2018.10.001 1 4 0 105 Mice|Animals|*Lateral Ventricles|phosphinothricin|*Animals, Newborn|*Neural Stem Cells|*Aminobutyrates|Neurogenesis|Cell Movement|Cell Differentiation|Neurons|Cell Proliferation|Primary Cell Culture|Cells, Cultured|*Herbicides|Mice, Inbred C57BL|Celsr2 protein, mouse|Cadherins 106 CELSR2 29862454 Immunogenetics 2018 10.1007/s00251-018-1065-3 0 0 0 105 Humans|Cattle|Animals|Female|*Milk|*Genome-Wide Association Study|Streptococcus uberis|*Streptococcus|Mastitis, Bovine|Lactation|Dairy Industry|Streptococcal Infections|Mammary Glands, Animal|Counts, Cell|*Leukocytes|*Phenotypes|Mastitis 106 CELSR2 29618362 BMC Med Genomics 2018 PMC5885375 10.1186/s12920-018-0355-9 6 11 0 105 Humans|Mice|Animals|*Mice, Knockout|*Neural Tube Defects|Neurulation|Cell Polarity|*Genetic Testing|Heterozygotes|Wnt Pathway|Mutation|Phenotypes 106 CELSR2 29489009 Histol. Histopathol. 2018 10.14670/HH-11-979 5 1 0 105 Humans|Receptor, ErbB-2|Receptors, Estrogen|Receptors, Progesterone|Immunohistochemistry|Carcinoma, Ductal, Breast|CELSR2 protein, human|*Cadherins|Biomarkers, Tumor|Triple Negative Breast Neoplasms|*Genes, Regulator|ING4 protein, human|Homeodomain Proteins|Cell Cycle Proteins|Tumor Suppressor Proteins 106 celsr3 30257206 Cell Rep 2018 PMC6475626 10.1016/j.celrep.2018.08.082 13 0 0 177 Humans|*Tourette Syndrome|*DNA Copy Number Variations|Autism Spectrum Disorder|*Cell Polarity|Sequencing, Whole Exome|Genetic Predisposition to Disease|Obsessive Compulsive Disorder|Cadherins 78 celsr3 30231850 BMC Genet. 2018 PMC6146521 10.1186/s12863-018-0673-0 2 0 0 177 *Exome|*Colorectal Cancer|*Mutations|Liver Neoplasms|Whole Exome Sequencing|*Neoplastic Processes|*Colonic Neoplasms|Transcriptome 78 celsr3 29618362 BMC Med Genomics 2018 PMC5885375 10.1186/s12920-018-0355-9 6 11 0 177 Humans|Mice|Animals|*Mice, Knockout|*Neural Tube Defects|Neurulation|Cell Polarity|*Genetic Testing|Heterozygotes|Wnt Pathway|Mutation|Phenotypes 78 celsr3 29327175 J. Neurooncol. 2018 10.1007/s11060-018-2749-0 8 1 0 177 Humans|*RNA, Micro|Neoplasm Recurrence, Local|Central Nervous System Neoplasms|Lymphoma, Non-Hodgkin|Prognosis|Lymphoma, Large B-Cell, Diffuse|Biomarkers, Tumor|ROC Curve|Area Under Curve|Specificity|Case-Control Studies|Cohort Studies 78 cenpb 30445992 Epigenetics Chromatin 2018 PMC6238281 10.1186/s13072-018-0237-6 0 0 0 198 *Centromeres|Centromere Protein A|Kinetochore|Chromosomal Proteins, Non-Histone|Centromere Protein B|Chromatin|Chromosome Segregation|Histones|Mitosis|Autoantigens|DNA-Binding Proteins|Protein Binding 183 cenpb 30075081 ACS Synth Biol 2018 PMC6154217 10.1021/acssynbio.8b00230 5 0 0 198 Humans|Cricetinae|Animals|*Chromosomes, Artificial, Human|*Cancer|*Centromere|Kinetochores|Chromatin|Epigenesis, Genetic|Cricetulus|CHO Cells|Gene Transfer Techniques|DNA Array 183 cenpb 29565577 ACS Synth Biol 2018 PMC5951608 10.1021/acssynbio.8b00018 6 0 0 198 Humans|*Centromeres|Human Artificial Chromosome|Centromere Protein A|Kinetochores|Histone H3|Chromatin|DNA, Satellite|Chromosomal Proteins, Non-Histone|*Human Chromosome|Epigenesis, Genetic|*Epigenetic|Cell Line, Tumor 183 cenpb 29386331 Genes Dev. 2018 PMC5828391 10.1101/gad.307736.117 4 0 0 198 Humans|*Chromatin|Centromere Protein A|Centromeres|Centromere Protein B|Chromosomal Proteins, Non-Histone|Kinetochores|DNA, Satellite|Autoantigens|*Molecular Conformation|In Situ Hybridization, Fluorescence 183 CES1P1 29457755 Pharmacogenomics 2018 10.2217/pgs-2016-0145 0 0 0 5 *Genotype|Carboxylic Ester Hydrolases|Polymorphism, Single Nucleotide|*Nucleotides 20 CES1P1 29427553 Drug Metab Pers Ther 2018 10.1515/dmpt-2017-0023 0 0 0 5 *Genotype|*Genotyping Techniques|Carboxylesterase|Carboxylic Ester Hydrolases|PCR|Single Nucleotide Polymorphisms|Haplotype|Promoter Regions, Genetic 20 CFDP1 29455858 Am. J. Hum. Genet. 2018 PMC5985266 10.1016/j.ajhg.2018.01.015 24 0 0 43 Humans|*Blood Pressure|*Genome-Wide Association Study|SNPs|Systole|Asian|*Blood Pressure Determination|Genetic Loci|European Continental Ancestry Group|*Smoking Behavior|Diastole 40 CHI3L2 29728799 Cancer Chemother. Pharmacol. 2018 10.1007/s00280-018-3594-8 5 0 0 30 Humans|*Neoadjuvant Therapy|DNA Topoisomerases, Type II|Receptor, ErbB-2|Chemotherapy, Adjuvant|Anthracyclines|Gene Amplification|Antigens, Neoplasm|Poly-ADP-Ribose Binding Proteins|Antineoplastic Combined Chemotherapy Protocols|Epirubicin|Biomarkers, Tumor|Disease-Free Survival|In Situ Hybridization, Fluorescence|DNA-Binding Proteins|CCL18 protein, human|*Chemokines, CC|*Macrophages 35 CHI3L2 29331073 Ann. Neurol. 2018 10.1002/ana.25143 18 0 0 30 *Amyotrophic Lateral Sclerosis|Proteomics|Neurodegenerative Diseases|*Biomarkers|Neurofilament Proteins|Hexosaminidases|*Macrophage|Disease Progression|Case-Control Studies 35 CHRFAM7A 30308236 Neurosci. Lett. 2018 PMC6320298 10.1016/j.neulet.2018.10.010 1 3 0 87 Animals|Humans|Mice|*alpha7 Nicotinic Acetylcholine Receptor|*Neurons|alpha-Bungarotoxin|Transgenic Mouse|Cell Line|*Biophysical Phenomena 57 CHRFAM7A 30258274 Curr. Genomics 2018 PMC6128389 10.2174/1389202919666180330153842 4 0 0 87 Humans|Adult|*DNA Copy Number Variations|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|Schizophrenia|Alzheimer Disease|Gene Deletion 57 CHRFAM7A 30089821 Eur. J. Hum. Genet. 2018 PMC6244195 10.1038/s41431-018-0223-2 1 1 0 87 *Varenicline|*Tobacco Use Disorder|Receptors, Nicotinic Acetylcholine|alpha7 Nicotinic Acetylcholine Receptor|Polymorphism, Genetic|Smoking|*DNA Mutational Analysis|Case-Control Studies|Promoter Regions, Genetic 57 CHRFAM7A 29784875 J. Biol. Chem. 2018 PMC6036215 10.1074/jbc.RA117.001698 3 0 0 87 Humans|*Nicotinic Receptor|alpha7 Nicotinic Acetylcholine Receptor|Allosteric Regulation|Acetylcholine 57 CHRFAM7A 29305655 J Neural Transm (Vienna) 2018 10.1007/s00702-017-1833-5 0 0 0 87 Humans|*Antipsychotic Agents|*Schizophrenia|*Gene Expression|alpha7 Nicotinic Acetylcholine Receptor|Psychotic Disorders|Nicotinic Acetylcholine Receptor|Smoking|Cognition 57 CILP2 30450639 J. Orthop. Res. 2018 10.1002/jor.24178 4 0 0 28 Humans|Dogs|Animals|*Hip Dysplasia, Canine|Epithelial-Mesenchymal Transition|Hedgehog Proteins|*Hip|Hip Osteoarthritis|Hip Dislocation, Congenital|Hip Joint|*Gene Expression|HHIP protein, human|*Membrane Glycoproteins|Dog Diseases|Chromosome Mapping|Phenotype|DACT2 protein, human|Carrier Proteins|Neoplasm Proteins 34 CILP2 30311632 Cancer 2018 PMC6214707 10.1002/cncr.31645 1 0 0 28 Adult|Humans|Child|Genome-Wide Association Study|*Osteosarcoma|Bone Neoplasms|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Complement Factor B|Genotype|Case-Control Studies|European Continental Ancestry Group|Risk Factors 34 CILP2 29321358 J. Genet. 2018 10.1007/s12041-017-0864-x 1 0 0 28 Humans|PCSK9 protein, human|Proprotein Convertase 9|*Dyslipidemia|High Density Lipoprotein Cholesterol|Low Density Lipoprotein Cholesterol|Genetic Susceptibility|Triglycerides|SNPs|Genetic Association Studies|*Chinese|Genetic Loci|Genome-Wide Association Study|Lipids|Apolipoproteins E|Genotype|Hypercholesterolemia|Hypertriglyceridemia|HMGCR protein, human 34 CISD1 30366664 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.10.101 0 0 0 191 Mice|Animals|Diabetes Mellitus, Type 2|*Adipose Tissue, White|*Muscle, Skeletal|Mitochondrial Proteins|Physical Conditioning, Animal|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Mitochondria|Mitochondrial Biogenesis|Transcription Factors|Insulin Resistance|Adaptation, Physiological|Western Blotting 84 CISD1 30206337 Int J Obes (Lond) 2018 10.1038/s41366-018-0203-1 1 0 0 191 Humans|*Adipocyte|*Adipose Tissue|Adipogenesis|Subcutaneous Fat|Intra-Abdominal Fat|Obesity|Body Mass Index|*Mitochondria|Gene Expression|Biomarkers|Thyrotropin 84 CISD1 30204426 Biochemistry 2018 10.1021/acs.biochem.8b00777 2 0 0 191 Humans|Animals|CISD1 protein, human|Mitochondrial Proteins|apoferredoxin|Ferredoxins|Iron-Sulfur Proteins|Mitochondrial Membrane, Outer|Aconitase|Redox|Mitochondria|Cytosol|Iron 84 CISD1 29704621 Free Radic. Biol. Med. 2018 10.1016/j.freeradbiomed.2018.04.569 1 5 0 191 *Kinetics|*Electrons|*Mitochondrial Membranes|CISD1 protein, human|*Mitochondrial Proteins|*Electron Transport|Iron-Sulfur Proteins|Redox|Pioglitazone|Thiazolidinediones|*Membrane Proteins|Mitochondria|*Cell Respiration|Energy Metabolism|Flavin Mononucleotide 84 CISD1 29666474 Cell Death Differ. 2018 PMC6294797 10.1038/s41418-018-0108-5 3 7 0 191 Animals|Humans|*Caenorhabditis elegans|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Caenorhabditis elegans Proteins|*Apoptosis|*Germ Line|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Caspases|*Cell Death|CASP3 protein, human|Caspase 3|Apoptosis Regulatory Proteins|Calcium-Binding Proteins|Mutations|Repressor Proteins 84 CISD1 29556009 Sci Rep 2018 PMC5859297 10.1038/s41598-018-23305-6 2 0 0 191 Humans|Animals|*Phylogeny|CISD3 protein, human|Iron-Sulfur Proteins|Mitochondrial Proteins|Amino Acid Sequence|Eukaryotes|*Sulfur|Evolution, Molecular|Archaea|Iron|Bacteria 84 CISD1 29463105 Antioxid. Redox Signal. 2018 10.1089/ars.2018.7502 20 2 0 191 *Reactive Oxygen Species|CISD1 protein, human|Mitochondrial Proteins|TYRP1 protein, human|*Oxidoreductases|Iron-Sulfur Proteins|*Membrane Glycoproteins|Iron|Cell Line, Tumor|Homeostasis|Protein Binding|Oxidative Stress|Antineoplastic Agents 84 CISD1 29435647 J. Biol. Inorg. Chem. 2018 PMC6006223 10.1007/s00775-018-1538-8 4 9 0 191 Humans|CISD1 protein, human|Mitochondrial Proteins|Iron-Sulfur Proteins|Mitochondrial Membranes|Mitochondria|Iron|Reactive Oxygen Species 84 CISD1 29311966 Front Physiol 2018 PMC5742148 10.3389/fphys.2017.01032 3 13 0 191 84 CIZ1 30456533 Pathol. Oncol. Res. 2018 10.1007/s12253-018-0495-4 0 0 0 143 Humans|Endothelial Cells|*Upregulation|Nuclear Protein|*Cell Cycle Proteins|Cell Proliferation|*Hemangioma|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|Gene Knockdown Techniques|Ciz1 protein, human 70 CIZ1 30280956 Cell Cycle 2018 PMC6226236 10.1080/15384101.2018.1526600 0 2 0 143 Humans|Female|Adult|Child|*Splicings, Alternative|Exons|Nuclear Proteins|DNA Replication|Cell Nucleus|Proliferating Cell Nuclear Antigen|Cell Cycle|Amino Acid Sequence|Tumors|Cell Proliferation|X Chromosome|DNA|Ciz1 protein, human 70 CIZ1 30218363 Methods Mol. Biol. 2018 10.1007/978-1-4939-8766-5_9 1 0 0 143 Mice|Animals|*Epitopes|*X Chromosome|Nuclear Matrix|X Chromosome Inactivation|Cell Nucleus|Nuclear Proteins|Fluorescent Antibody Technique|RNA, Long Noncoding|Microscopy, Fluorescence 70 CIZ1 30107825 BMC Cancer 2018 PMC6092802 10.1186/s12885-018-4705-y 2 1 0 143 Uveal melanoma|*Uveal Neoplasms|*Melanoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|DNA Copy Number Variations|Genomics|Mutation|DNA 70 CIZ1 30098009 FEBS Lett. 2018 PMC6275157 10.1002/1873-3468.13221 0 1 0 143 Animals|Mice|Cre recombinase|*Cell Cycle Proteins|*Genes, cdc|*Exon|Nuclear Proteins|Cell Cycle|DNA Replication|Mice, Knockout|Alternative Splicing|DNA Damage|Cells, Cultured|Fibroblasts|Ciz1 protein, mouse 70 CIZ1 29748958 Prostate 2018 10.1002/pros.23650 7 3 0 143 Humans|Male|*miRNA|Gene Expression Regulation, Neoplastic|Circulating MicroRNA|Prostatic Neoplasms, Castration-Resistant|Gene Expression Profiling|Cell Line, Tumor|Cell Proliferation|Gene Expression 70 CKAP2 30119212 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.07.104 0 3 0 245 Humans|Mice|Adolescent|Animals|Child|Mice, Nude|*Osteosarcoma|*Cell Proliferation|*Cell Cycle Arrest|*Apoptosis|Bone Neoplasms|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|JAK2 protein, human|Janus Kinase 2|CCND1 protein, human|Cyclin D1|Cell Line, Tumor|RNA Interference|Cell Movement|Signal Transduction|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2 50 CKAP2 30066946 Oncol. Rep. 2018 PMC6111633 10.3892/or.2018.6611 4 13 0 245 Humans|*Prognosis|*Glioma|Brain Neoplasms|Neoplasm Grading|Cell Proliferation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Cell Cycle|Apoptosis|Survival Rate|RNA, Messenger|Real-Time Polymerase Chain Reaction|Survival Analysis|CKAP2 protein, human|Cytoskeletal Proteins 50 CKAP2 29863662 J Vis Exp 2018 PMC6101295 10.3791/57369 1 0 0 245 Humans|*Immunohistochemistry|*Paraffin Embedding|HeLa Cells|Tissue Fixation|*Proteomics|*Proteins|Formaldehyde|Staining|*Complement Factor B|*Protein Processing, Post-Translational 50 CLEC11A 30168613 Hepatology 2018 PMC6429916 10.1002/hep.30244 13 0 0 80 *Carcinoma, Hepatocellular|*Liver Neoplasms|AFP protein, human|alpha Fetoprotein|Receiver Operating Characteristics|Liver Cirrhosis|AUC|Biomarkers, Tumor|Specificity|Early Detection of Cancer|*DNA|Case-Control Studies 32 CLEC11A 29956722 Int. J. Mol. Med. 2018 PMC6089755 10.3892/ijmm.2018.3739 6 0 0 80 Humans|*Leukemia, Myeloid, Acute|Prognosis|Gene Expression Regulation, Leukemic|Gene Expression Profiling|*Risk Assessment|Transcriptome|Kaplan-Meier Estimate|RNA, Messenger|Biomarkers, Tumor|Multivariate Analysis 32 CLIC4 30582444 Circ. Res. 2018 PMC6325770 10.1161/CIRCRESAHA.118.313705 3 5 0 385 Monocrotaline|Familial Primary Pulmonary Hypertension|Hypertension, Pulmonary|Bone Morphogenetic Protein Receptors, Type II|Pulmonary Artery|CLIC4 protein, human|*Chloride Channels|Muscle, Smooth, Vascular|Endothelial Cells|Signal Transduction|Cells, Cultured 122 CLIC4 30389639 J. Biotechnol. 2018 10.1016/j.jbiotec.2018.10.008 2 0 0 385 Cricetinae|Animals|*CHO Cells|*Cricetulus|Chromatography, Liquid|Proteomics|Tandem Mass Spectrometry|miRNAs|USP14 protein, human|*Ubiquitin Thiolesterase|*Cell Density|Cell Proliferation|Up-Regulation|Culture, Batch|Ubiquitins 122 CLIC4 30381396 J. Biol. Chem. 2018 PMC6302171 10.1074/jbc.RA118.002779 4 5 0 385 DIAPH3 protein, human|*Formins|PFN1 protein, human|*Profilins|RHOA protein, human|*rhoA GTP-Binding Protein|CLIC4 protein, human|*Channel, Chloride|*Signal Transduction|Filopodia|Actin|*Protein Binding|Cell Movement|lysophosphatidic acid|Lysophospholipids|*Cytoplasm|Cell Adhesion|Plasma Membrane 122 CLIC5 30575790 Sci Rep 2018 PMC6303392 10.1038/s41598-018-36894-z 3 0 0 111 Humans|Mice|Animals|*Hair Cells, Cochlear|Stereocilia|Hair Cells, Auditory, Inner|Hearing Loss|Deafness|MicroRNAs|MIRN183 microRNA, human|Mirn183 microRNA, mouse 55 CLIC5 30235455 Kidney Blood Press. Res. 2018 10.1159/000493657 2 1 0 111 *Cardio-Renal Syndrome|*Proteomics|*Heart Failure|*Kidney|Renin-Angiotensin System 55 CLIC5 30133498 PLoS ONE 2018 PMC6105016 10.1371/journal.pone.0202537 0 0 0 111 Humans|*Herpesvirus 4, Human|Epstein Barr Virus Infection|EBV-encoded nuclear antigen 1|Epstein-Barr Virus Nuclear Antigens|*B-Lymphocytes|*Next Generation Sequencing|Virus Latency|Gene Expression Regulation, Viral|miRNAs|Viral Proteins|RNA, Viral|Epigenesis, Genetic|*Big Data|Host-Pathogen Interactions|*Data Mining|Long Non-Coding RNA|*Epigenetic 55 CLIC5 29425878 Exp. Eye Res. 2018 PMC5878992 10.1016/j.exer.2018.02.001 1 0 0 111 Mice|Animals|*Lens, Eye|Cataract|Mice, Knockout|Epithelial Cells|Eye Proteins|Cell Differentiation|Northern Blots|*Lenses|mRNA|Blotting, Western|Disease Models, Animal|Cilia|Sutures|Lctl protein, mouse|Glycoside Hydrolases|Membrane Proteins|CLIC5 protein, mouse|Chloride Channels 55 CLIC5 29338044 PLoS ONE 2018 PMC5770019 10.1371/journal.pone.0190817 6 7 0 111 Mice|Humans|Animals|Proteomics|Cataract, Autosomal Dominant|*Cataract|alpha-Crystallin A Chain|Lens, Eye|alpha-Crystallin B Chain|*Mutations|Gene Knock-In Techniques|Heterozygote|Disease Models, Animal|*Gene Expression 55 CLIC6 29869218 J. Assist. Reprod. Genet. 2018 PMC6086797 10.1007/s10815-018-1199-0 2 0 0 37 Humans|Female|*Long Non-Coding RNA|*Ovarian Hyperstimulation Syndrome|Gene Regulatory Networks|Gene Expression Profiling|RNA, Messenger|Gene Expression Regulation, Neoplastic|*Genetic Profile 21 CLIC6 29720717 Sci Rep 2018 PMC5931990 10.1038/s41598-018-25231-z 1 2 0 37 Mice|Animals|Scattering, Small Angle|X-Ray Diffraction|*Crystallography|Protein Conformation|Molecular Dynamics Simulation|Oxidation-Reduction|Chloride Channels 21 CLMN 29933226 J Pharm Biomed Anal 2018 10.1016/j.jpba.2018.06.016 1 0 0 48 *RNA-Seq|*Transcriptome Analysis|*Myocardial Infarction|Oligonucleotide Array Sequence Analysis|Myocardium|*Whole Exome Sequencing|Gene Expression Regulation|RNA, Messenger|Drugs, Chinese Herbal|Real-Time Polymerase Chain Reaction 29 CLMN 29484395 Int. J. Oncol. 2018 PMC5843394 10.3892/ijo.2018.4281 2 7 0 48 *Long Non-Coding RNA|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|5 Fluorouracil|Gene Expression Profiling|Gene Regulatory Networks|Bioinformatics|RNA, Messenger|Biomarkers, Tumor|*Colonic Neoplasms|Cell Movement|Proto-Oncogene Proteins c-akt|Cell Line, Tumor|Downregulation|Upregulation|Gene Expression|Microarray Analysis 29 CLMP 30591579 Glob Health Sci Pract 2018 PMC6370361 10.9745/GHSP-D-18-00067 1 0 0 63 Pregnancy|Humans|*Leadership|*Universal Health Insurance|Zambia|Nurse, Head|Primary Healthcare|Nurse's Role|Health Workforce|Nurse-Midwives|Clinical Competence|*Institutionalizations|Focus Group|Rural Population 584 CLMP 30450519 Bull. Exp. Biol. Med. 2018 10.1007/s10517-018-4289-1 0 0 0 63 Humans|*Enterovirus|*Enterovirus Infections|Coxsackie B Virus|Oncolytic Viruses|Coxsackie and Adenovirus Receptor-Like Membrane Protein|Oncolytic Virotherapy|Poliovirus|Receptors, Virus|*Receptors, Cell Surface|Cell Line, Tumor|Virus Replication 584 CLMP 30385615 Cancer Res. 2018 10.1158/0008-5472.CAN-18-1742 1 3 0 63 *Proto-Oncogene Proteins c-akt|*Tight Junctions|PTEN protein, human|PTEN Phosphohydrolase|Epithelial-Mesenchymal Transition|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|MicroRNAs|Apoptosis|Phosphorylation|Tumor Cells, Cultured 584 CLMP 29361518 Dis Model Mech 2018 PMC5894946 10.1242/dmm.032128 2 2 0 63 Humans|Mice|Animals|GJA1 protein, human|*Connexin 43|*CAR-Like Membrane Protein|connexin 45|*Connexins|*Muscle Contraction|Gap Junctions|Muscle, Smooth|*Intestines|*Cell Adhesion Molecules|Myocytes, Smooth Muscle|Congenital Short Bowel Syndrome|*Immunoglobulin|*Cell Adhesion 584 CLN8 30453012 Biochim Biophys Acta Mol Basis Dis 2018 10.1016/j.bbadis.2018.11.011 0 3 0 146 Humans|*Neuronal Ceroid-Lipofuscinoses|*Membrane Protein|Glycogen Synthase Kinase 3|*Endoplasmic Reticulum|N-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine|*Ceramides|Golgi Apparatus|Protein Transport|Lysosomes|SET protein, human|Transcription Factors|Histone Chaperones|Protein Binding|Signal Transduction|4-Chloro-7-nitrobenzofurazan|CLN8 protein, human 130 CLN8 30397314 Nat. Cell Biol. 2018 PMC6277210 10.1038/s41556-018-0228-7 0 6 0 146 *Endoplasmic Reticulum|*Lysosome|Neuronal Ceroid-Lipofuscinoses|Golgi Apparatus|Membrane Proteins|Protein Transport|Cell Line|Mutation 130 CLN8 30250865 Ann Clin Transl Neurol 2018 PMC6144451 10.1002/acn3.625 4 5 0 146 Humans|*Neuronal Ceroid-Lipofuscinoses|flupirtine|*Aminopyridines|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Aminopeptidases|Serine Proteases|Membrane Proteins|Molecular Chaperones|Membrane Glycoproteins|Endopeptidases|Apoptosis|Cell Line|Ceramides|Neurons|RNA, Messenger 130 CLN8 29961513 Semin Pediatr Neurol 2018 10.1016/j.spen.2018.04.002 0 0 0 146 *Epilepsy|*Mutation|NAV1.2 Voltage-Gated Sodium Channel|*Epilepsy, Generalized|*Brain Diseases|Genetic Predisposition to Disease|Mutation, Missense 130 CLN8 29890939 BMC Genomics 2018 PMC5996463 10.1186/s12864-018-4759-x 3 0 0 146 Animals|*Buffaloes|Iran|*Breeding|Selection, Genetic|Genome-Wide Association Study|Genomics|Quantitative Trait Loci|Genotype|Phenotypes|Polymorphism, Single Nucleotide|*Bison 130 CLN8 29632068 J. 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Pollut. 2018 10.1016/j.envpol.2018.05.026 0 0 0 70 Humans|*Polycyclic Aromatic Hydrocarbons|*Telomere|Cohort Studies|*Prospective Studies|Coke|1-hydroxypyrene|Pyrenes|*Telomere Shortening|Air Pollutants, Occupational|Occupational Exposure|Leukocytes|TERT protein, human|Telomerase|CLPTM1L protein, human|Membrane Proteins|Neoplasm Proteins 151 CLPTM1L 30079703 Balkan Med J 2018 PMC6335938 10.4274/balkanmedj.2018.0356 0 0 0 70 Humans|*Multiple Myeloma|*Bone Marrow|*Transcriptome Analysis|*Gene Expressions|Flow Cytometry|B Cells 151 CLPTM1L 30042348 Int J Mol Sci 2018 PMC6121261 10.3390/ijms19082161 1 4 0 70 *Plasma Cells|*Transcriptome|*Cell Surface Proteins|Antibody-Secreting Cells|B-Lymphocytes|Production, Antibody|Humoral Immunity|Multiple Myeloma|Bone Marrow Cells|Cell Differentiation 151 CLPTM1L 29939218 Carcinogenesis 2018 10.1093/carcin/bgy084 0 0 0 70 Humans|Genome-Wide Association Study|*Asian|*Lung Cancer|Genetic Predisposition|SNPs|Transcriptase, Telomerase Reverse|Linkage Disequilibrium|Neoplasm Proteins|Haplotypes|Membrane Proteins|Carcinoma, Squamous Cell|Genotype|Case-Control Studies|TERT protein, human|CLPTM1 protein, human|CLPTM1L protein, human 151 CLSTN2 30582855 Probl Radiac Med Radiobiol 2018 10.33145/2304-8336-2018-23-331-350 0 0 0 215 Humans|*Ionizing Radiation|Radiation Exposure|Chernobyl Nuclear Accident|Radiation Dosage|Radiation Injuries|Occupational Exposure|Emergency Responders|Radiation Monitoring|*Biological Markers|Case-Control Studies|Gene Expression 32 CLSTN2 30283697 Evol Lett 2018 PMC6145502 10.1002/evl3.81 3 0 0 215 Vesicular Monoamine Transport Proteins|Genotype|Polymorphism, Single Nucleotide|Case-Control Studies 32 CLSTN2 29991755 Cell Death Dis 2018 PMC6039476 10.1038/s41419-018-0813-5 9 4 0 215 Humans|Child|*RNA, Long Noncoding|*miRNAs|*mRNA|*Osteosarcoma|Gene Regulatory Networks|*Sequencing, RNA|Gene Expression Regulation, Neoplastic|*Tumorigenesis|*Cell Transformation, Neoplastic|Gene Ontology|Biomarkers, Tumor|Computational Biology|Transcriptome|*Whole Exome Sequencing|*Lung Neoplasms|Kaplan-Meier Estimate 32 CMPK2 30083606 Sci Adv 2018 PMC6070316 10.1126/sciadv.aat0843 4 6 0 29 Animals|Humans|HIV-1|Interferon-alpha|Antiviral Agents|CD4-Positive T-Lymphocytes|*Interferon Type I|Virus Replication|HIV Infections|Simian Immunodeficiency Virus|Dendritic Cells 21 CMPK2 30046112 Nature 2018 PMC6329306 10.1038/s41586-018-0372-z 81 4 0 29 *Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|DNA, Mitochondrial|Mitochondria|Macrophages|Interleukin-1beta|Reactive Oxygen Species|Lipopolysaccharides|Signal Transduction 21 CNDP1 30485136 Am. 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Nephrol. 2018 10.1016/j.semnephrol.2018.05.002 2 0 0 125 Humans|*Precision Medicine|APOL1 protein, human|Apolipoprotein L1|*End Stage Kidney Disease|Apolipoproteins|Genetic Predisposition to Disease|Focal Segmental Glomerulosclerosis|Lipoproteins, HDL|Polymorphism, Single Nucleotide|Molecular Motor Proteins|Myosin Heavy Chains|Genotype|*Genomics|African Continental Ancestry Group|African Americans 70 CNDP1 29961141 Amino Acids 2018 10.1007/s00726-018-2602-y 1 0 0 125 Humans|*Albuminuria|aminoacyl-histidine dipeptidase|*Diabetes Mellitus, Type 2|Dipeptidases|Diabetic Nephropathy|Glomerular Filtration Rate|Kidney|Cohort Studies 70 CNDP1 29922921 Amino Acids 2018 10.1007/s00726-018-2601-z 2 2 0 125 Humans|aminoacyl-histidine dipeptidase|CNDP1 protein, human|*Dipeptidases|Diabetic Nephropathy|Carnosine 70 CNDP1 29907817 Sci Rep 2018 PMC6003912 10.1038/s41598-018-27265-9 2 0 0 125 Female|Pregnancy|Humans|*Proteomics|*Carotid Atherosclerosis|*Atherosclerosis|Plaques, Atherosclerotic|*Biomarkers|Receiver Operating Characteristic|Ultrasonography|Blood Proteins|Risk Factors|*Premature Birth|CNDP1 protein, human|Dipeptidases 70 CNDP1 29689304 J Proteomics 2018 10.1016/j.jprot.2018.04.029 4 0 0 125 *Carcinoma, Renal Cell|*Proteomics|*Renal Veins|Tandem Mass Spectrometry|Renal Cancer|*Liquid Biopsies|Proteome|Chromatography, Liquid|Biomarkers, Tumor|Kidney|*Plasma|*Body Fluids 70 CNDP1 29402779 J Nutrigenet Nutrigenomics 2018 10.1159/000485798 2 0 0 125 *Dietary Carbohydrate|*Carotene|dipeptidase|Dipeptidases|aminoacyl-histidine dipeptidase|*Obesity|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Diabetic Nephropathies|Genotype|Diabetes Mellitus, Type 2|Case-Control Studies|Risk Factors 70 CNDP1 29360682 Pharmacogenet. Genomics 2018 PMC5805126 10.1097/FPC.0000000000000326 1 1 0 125 Adult|Child|Humans|*Transcriptome|Renin-Angiotensin System|Peptidyl-Dipeptidase A|Angiotensinogen|Blood Pressure|Hypertension|*Liver|Polymorphism, Genetic 70 CNGB3 30592498 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24328 0 0 0 35 Mice|Animals|Achromatopsia 1|*Color Vision Defects|Photoreceptor, Cone|Cyclic Nucleotide-Gated Cation Channels|Electroretinography|Retinal Rod Photoreceptor Cells|DNA Mutational Analysis|Pedigree|Mutation|Phenotype 153 CNN3 30518778 Sci Rep 2018 PMC6281606 10.1038/s41598-018-35948-6 3 0 0 296 *Stress Fibers|*Actins|calponin|*Microfilament Proteins|*Calcium-Binding Proteins|Actin Cytoskeleton|Actomyosin|*Muscle Contraction|Cell Movement|RNAi|Osteosarcoma|Formins|Cell Line, Tumor 39 CNN3 30299231 Radiology 2018 10.1148/radiol.2018180513 10 0 0 296 Humans|*Heart Ventricles|*Deep Learning|Retrospective Studies|*Left Ventricular Function|MRI, Cine|*Magnetic Resonance Imaging|Image Interpretation, Computer-Assisted|Neural Networks, Computer|Algorithms|Myocardium|Reproducibility of Results 39 CNN3 30114595 Transl Oncol 2018 PMC6097464 10.1016/j.tranon.2018.07.014 7 11 0 296 Humans|*Colorectal Cancer|Peritoneal Neoplasms|CDH1 protein, human|E Cadherin|*Peritoneum|Biomarkers, Tumor|EPSTI1 protein, human|Neoplasm Proteins|Cell Line, Tumor|Signal Transduction|*Colonic Neoplasms|Mutation|Sequencing, Whole Exome|mRNA|Antigens, CD 39 CNN3 30035122 Biomed Res Int 2018 PMC6033250 10.1155/2018/4605191 4 0 0 296 Humans|*Neural Networks, Computer|Mammography|Machine Learning|Diagnosis, Computer-Assisted|ROC Curve|Biopsy 39 CNN3 29885947 Exp. Hematol. 2018 10.1016/j.exphem.2018.06.001 0 0 0 296 Humans|*Transplantation, Autologous|*Hematopoietic Stem Cell Transplantation|*Transcriptome|Leukocytes, Mononuclear|Transplantation Conditioning|Multiple Myeloma|Lymphoma|Malignancies, Hematological 39 CNPY2 30415246 Cell. Physiol. Biochem. 2018 10.1159/000495048 1 0 0 91 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Immunohistochemistry|Cell Proliferation|Kaplan-Meier Estimate|Cell Line, Tumor|Apoptosis|Proportional Hazards Models|Disease Progression|Tumor Microenvironment|CNPY2 protein, human|Adaptor Proteins, Signal Transducing 27 CNPY2 30070972 Aging (Albany NY) 2018 PMC6128441 10.18632/aging.101512 3 5 0 91 Humans|Early Detection of Cancer|CEACAM5 protein, human|Carcinoembryonic Antigen|*Colorectal Cancer|CA-19-9 Antigen|Biomarkers, Tumor|*Protein Isoforms|Receiver Operating Characteristic|*Colonic Neoplasms|GPI-Linked Proteins|CNPY2 protein, human|Adaptor Proteins, Signal Transducing 27 CNPY2 29864955 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.04.123 0 3 0 91 Humans|*Carcinoma, Non-Small-Cell Lung|*Cisplatin|*Lung Neoplasms|*Apoptosis|Antineoplastic Agents|Signal Transduction|Drug Resistance, Neoplasm|NF-kappa B|Cell Line, Tumor|Cell Proliferation|Upregulation|RNA Interference|Lung|CNPY2 protein, human|Adaptor Proteins, Signal Transducing 27 CNPY2 29849941 Oncotarget 2018 PMC5966250 10.18632/oncotarget.25110 3 1 0 91 *Proteomics|*Protein A|Paraffin Embedding|Tissue Fixation|Chromatography, Liquid|Proteome|Pancreatic Neoplasms|Tandem Mass Spectrometry|Formaldehyde|Peptides|*Liver Neoplasms 27 CNPY2 29707137 Oncotarget 2018 PMC5915145 10.18632/oncotarget.24824 1 62 0 91 Humans|Male|AR protein, human|*Receptors, Androgen|*Proteolysis|*Prostate|*Prostate Cancer|Ubiquitination|E3 Ubiquitin Ligase|Ubiquitin|Cell Line, Tumor|Signal Transduction|Transcription, Genetic|Cell Proliferation|Up-Regulation|Gene Expression Regulation, Neoplastic|Transcription Factor|MYLIP protein, human|CNPY2 protein, human|Adaptor Proteins, Signal Transducing 27 CNPY2 29569784 Cell Biol. Int. 2018 10.1002/cbin.10961 1 6 0 91 *Carcinoma, Non-Small-Cell Lung|*Epithelial-Mesenchymal Transition|*Glycogen Synthase Kinase 3|*Proto-Oncogene Proteins c-akt|*Lung Neoplasms|CDH1 protein, human|E Cadherin|Snail Family Transcription Factors|Cell Movement|Signal Transduction|Antigens, CD|Cell Line, Tumor|Adenocarcinoma|RNA Interference|Cell Proliferation|Phosphorylation|RNA, Small Interfering|Transcription Factors 27 COBLL1 30135119 J. Virol. 2018 PMC6189496 10.1128/JVI.01362-18 2 4 0 74 EBNA-3C, epstein-barr virus|*Epstein-Barr Virus Nuclear Antigens|Epstein Barr Virus|lymphocryptovirus nuclear antigen 3C|*Antigens, Viral|*Viral Proteins|RBPJ protein, human|Immunoglobulin J Recombination Signal Sequence-Binding Protein|Epstein-Barr Virus Infections|B Cells|Chromatin Immunoprecipitation|Cell Line 29 COBLL1 30089489 BMC Med Genomics 2018 PMC6083526 10.1186/s12920-018-0380-8 1 6 0 74 Pregnancy|Humans|Female|*Glucose Intolerance|Diabetes Mellitus, Type 2|Gestational Diabetes|Genetic Predisposition to Disease|*Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Genetic Association Studies|*Risk Factors|Alleles|Genotype|Insulin Resistance|India 29 COBLL1 30071822 BMC Psychiatry 2018 PMC6090917 10.1186/s12888-018-1822-8 1 1 0 74 Humans|*Autism Spectrum Disorder|*Tourette Syndrome|NAV1.3 Voltage-Gated Sodium Channel|NAV1.2 Voltage-Gated Sodium Channel|NAV1.1 Voltage-Gated Sodium Channel|Seizures|*Heterozygote|Mutations|Genetic Predisposition to Disease|SCN3A protein, human|Sodium Channels|SCN2A protein, human 29 COBLL1 29686105 Proc. 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Reprod. 2018 10.1093/humrep/dey319 8 0 0 109 Humans|Male|*Infertility, Male|CpG Islands|Sperm|Spermatogenesis|DNA Methylation|Fertility 40 CPEB2 30322039 Int J Mol Sci 2018 PMC6214008 10.3390/ijms19103138 1 22 0 109 Female|Pregnancy|Swine|Animals|*Embryonic Development|Oocytes|Oogenesis|Parthenogenesis|Polyadenylation|RNA, Messenger, Stored|Blastocysts|mRNA|mRNA Cleavage and Polyadenylation Factors|Meiosis|RNA-Binding Proteins|Gene Expression Regulation, Developmental|Cytoplasm|Transcription Factors 40 CPEB2 30177570 EMBO J. 2018 PMC6187220 10.15252/embj.201899071 1 6 0 109 Humans|Animals|Mice|UCP1 protein, human|*Uncoupling Protein 1|*Adipose Tissue, Brown|*mRNA|*Thermogenesis|Mitochondrial Proteins|Mice, Knockout|Signal Transduction|Isoforms|CPEB2 protein, human|RNA-Binding Proteins|Ucp1 protein, mouse 40 CPEB2 30145997 Reprod. Fertil. Dev. 2018 10.1071/RD18098 0 1 0 109 Swine|Animals|*Polyadenylation|TJP1 protein, human|Tight Junction Protein 1|Morula|Occludin|Embryonic Development|Blastocyst|Tight Junctions|RNA, Messenger|Oocytes|Gene Expression Regulation, Developmental|Coxsackie and Adenovirus Receptor-Like Membrane Protein|Epithelium|3' Untranslated Region|RNA Binding Protein 40 CPEB3 29850575 Biomed Res Int 2018 PMC5932519 10.1155/2018/8403157 1 8 0 216 Humans|*Carcinoma, Hepatocellular|*Up-Regulation|*Liver Neoplasms|*Lidocaine|CPEB3 protein, human|*RNA-Binding Proteins|HepG2 Cells|Cell Proliferation|Apoptosis|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Survival|Gene Knockdown Techniques|RNA, Messenger 69 CPEB3 29707110 Oncotarget 2018 PMC5915118 10.18632/oncotarget.22457 10 10 0 216 Chick Embryo|Animals|*Muscle Development|*miRNA|*Chicken|mRNA|Gene Expression Profiling|Gene Regulatory Networks|Gene Expression Regulation, Developmental|Muscle, Skeletal 69 CPEB3 29332449 Technol. 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Sci. 2018 10.1167/iovs.18-24122 5 0 0 67 Humans|*Diabetic Retinopathy|*Proteomics|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Visual Acuity|Wet Macular Degeneration|Vitreous Body|Eye Proteins|Biomarkers|Tandem Mass Spectrometry|Enzyme-Linked Immunosorbent Assay|Diabetes Mellitus 65 CPVL 29922448 Bone Joint Res 2018 PMC5987685 10.1302/2046-3758.74.BJR-2017-0245.R1 5 4 0 67 *Transcriptome Analysis|Gene Regulatory Networks|*Osteoarthritis|Protein Interaction Maps|Transcriptome|Databases, Genetic|Computational Biology|*Biological Phenomena|Transcription Factors 65 CPVL 29787891 Res Dev Disabil 2018 10.1016/j.ridd.2018.05.005 0 0 0 67 Infant, Newborn|Humans|*Leukomalacia, Periventricular|*Cerebral Palsy|*Postural Balance|Neurologic Examination|Infant, Premature|Child Development 65 CPVL 29627403 Pulmonology 2018 10.1016/j.pulmoe.2018.02.008 0 0 0 67 Infant|Humans|Infant, Newborn|*Infant, Extremely Low Birth Weight|*Intensive Care Units, Neonatal|Respiratory Distress Syndrome, Newborn|Bronchopulmonary Dysplasia|Infant, Premature|Gestational Age|Respiration, Artificial 65 CPVL 29621770 Neonatology 2018 10.1159/000487505 0 1 0 67 Infant|Humans|Infant, Newborn|*Bronchopulmonary Dysplasia|*Leukomalacia, Periventricular|*Preterm Infants|*Risk Factors|*Infant, Very Low Birth Weight|*Infant, Premature, Diseases|Retinopathy of Prematurity|Gestational Age|Respiratory Distress Syndrome, Newborn|Birth Weight|3'-(1-butylphosphoryl)adenosine|*Complement Factor B|Morbidities 65 CPVL 29372809 Genetika 2018 5 0 0 67 Humans|*Genetic Markers|Genome-Wide Association Study|*Endophenotypes|*Schizophrenia|SNPs|Neurogranin|Genetic Predisposition to Disease|Genotype|Gene Frequency|Alleles|Asian Continental Ancestry Group|Case-Control Studies|CSMD1 protein, human|Membrane Proteins|Cognition|Russia|VRK2 protein, human|Protein-Serine-Threonine Kinases 65 CRELD1 30407909 Elife 2018 PMC6245729 10.7554/eLife.39649 0 1 0 38 Animals|*Acetylcholine|Caenorhabditis elegans Proteins|Caenorhabditis elegans|Receptors, Cholinergic|Neuromuscular Junction|Endoplasmic Reticulum|Carrier Proteins|*Biological Evolution|Plasma Membrane|*Regulatory Sequences, Nucleic Acid 32 CRELD1 30221396 J. Clin. Lab. Anal. 2018 PMC6818592 10.1002/jcla.22660 3 0 0 38 Child|Humans|*DNA Copy Number Variations|*Heart Defects, Congenital|Homeobox Protein Nkx-2.5|BMP4 protein, human|*Bone Morphogenetic Protein 4|GATA4 Transcription Factor|*Chinese|*Genes, Homeobox|T-Box Domain Proteins|Heart Septal Defects, Atrial|Genetic Predisposition to Disease|NKX2-5 protein, human|CRELD1 protein, human|Cell Adhesion Molecules|Extracellular Matrix Proteins|GATA4 protein, human 32 CRELD1 30007050 Hum. Mutat. 2018 10.1002/humu.23593 3 0 0 38 Humans|Atrioventricular Septal Defect|*Mutation, Missense|*Heart Septal Defects|*Heterozygote|*Transcription Factors|Down Syndrome|Phenotype|Amino Acid Sequence|Extracellular Matrix Proteins|Mutation|NFATC1 protein, human|NFATC Transcription Factors 32 CRELD1 29952356 Anatol J Cardiol 2018 PMC6237800 10.14744/AnatolJCardiol.2018.70481 1 0 0 38 Humans|*DNA Copy Number Variations|*Multiplex Polymerase Chain Reaction|*Number, Gene Copy|*Heart Defects, Congenital|BMP4 protein, human|Bone Morphogenetic Protein 4 32 CRIP1 30570412 Expert Rev Clin Immunol 2018 10.1080/1744666X.2019.1561283 3 0 0 104 Fluorodeoxyglucose F18|Positron-Emission Tomography|Multimodal Imaging|Bone Neoplasms|Tomography, X-Ray Computed|Magnetic Resonance Imaging|Prognosis|*Cartilage Diseases 80 CRIP1 30514397 Acta Neuropathol Commun 2018 PMC6278135 10.1186/s40478-018-0630-1 4 0 0 104 Child|Humans|Familial ependymoma|*Ependymomas|*Supratentorial Neoplasms|Glioma|Transcription Factor RelA|Brain Neoplasms|*Genes, Regulator|Oncogene Proteins, Fusion|Genetic Profile|Japan|CRIP1 protein, human|Carrier Proteins|LIM Domain Proteins|RELA protein, human|C11orf95 protein, human|Proteins 80 CRIP1 29959029 Life Sci. 2018 10.1016/j.lfs.2018.05.054 4 6 0 104 Humans|Female|*Epithelial-Mesenchymal Transition|*Uterine Cervical Neoplasms|*Cell Migration|*Wnt Signaling Pathway|beta Catenin|Cell Proliferation|Wnt Proteins|*Catenins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|siRNA|CRIP1 protein, human|Carrier Proteins|LIM Domain Proteins 80 CRNN 30322007 Sensors (Basel) 2018 PMC6210564 10.3390/s18103418 1 0 0 53 *Deep Learning|Neural Networks, Computer|*Sound Localization|Acoustic 59 CRNN 30285776 J Transl Med 2018 PMC6167794 10.1186/s12967-018-1642-0 3 0 0 53 Papillary Thyroid Microcarcinoma|*Cell Adhesion|*Carcinoma, Papillary|*Thyroid Neoplasms|Proto-Oncogene Proteins B-raf|Mutation|Lymphatic Metastasis|Adenocarcinoma 59 CRNN 30009832 J. 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Dermatol. 2018 10.1016/j.jid.2018.06.184 1 10 0 53 Humans|Mice|Animals|*Keratinocytes|*Phosphoinositide 3 Kinase|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|Imiquimod|Psoriasis|Skin|*Cell Proliferation|IL17A protein, human|IL-17A|Cytokines|Dermatitis|Epidermis|Epidermal Cells|Aminoquinolines|Signal Transduction|Disease Models, Animal|Phosphorylation 59 CRNN 29998367 Anal Bioanal Chem 2018 10.1007/s00216-018-1223-3 0 0 0 53 Humans|Female|Tandem Mass Spectrometry|Proteomics|*Nails|Chromatography, Liquid|Spectrometry, Mass, Electrospray Ionization|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|*Genomics|Body Fluids|Biomarkers|Profiling, DNA|Hemoglobin 59 CRNN 29990156 IEEE Trans Image Process 2018 10.1109/TIP.2017.2772836 2 0 0 53 *Deep Learning|Bayes Theorem|*Semi-supervised Learning|Neural Networks, Computer|Algorithm|Clustering 59 CRNN 29952759 Physiol Meas 2018 10.1088/1361-6579/aacfd9 4 0 0 53 Humans|*Shoulder|*Machine Learning|*Exercise Therapy|*Physical Therapy Modalities|Support Vector Machine|Algorithms|*Recognition, Psychology 59 CROCC 30404835 J. Cell. Sci. 2018 10.1242/jcs.222901 2 5 0 82 Humans|*Centrosome|Centrioles|Cell Cycle Proteins|Spindle Apparatus|Protein-Serine-Threonine Kinases|NIMA-Related Kinases|Interphase|Mitosis|Microtubule-Associated Proteins|Cytoskeletal Proteins|Phosphorylation|HeLa Cells|Cep250 protein, human|Autoantigens 32 CROCC 29784668 Mol. Cancer Res. 2018 10.1158/1541-7786.MCR-18-0062 3 0 0 82 Humans|*Tetraploidy|*Centrosome|*Colorectal Cancers|Instability, Microsatellite|Chromosomal Instability|Spindle Apparatus|*Phenotypes|Mitosis|Cell Transformation, Neoplastic 32 CROCC 29649211 PLoS Biol. 2018 PMC5918241 10.1371/journal.pbio.2003998 2 0 0 82 Humans|*Centrioles|*Interphase|Centrosome|polo-like kinase 1|Cell Cycle Proteins|Protein-Serine-Threonine Kinases|Proto-Oncogene Proteins|Mitosis|HeLa Cells|RNA, Small Interfering 32 CROCC 29463719 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC5873239 10.1073/pnas.1716840115 0 12 0 82 Humans|*Centrioles|*Centrosome|Interphase|Cytoskeletal Proteins|Microtubule-Associated Proteins|Cell Cycle Proteins|Microtubule-Organizing Center|NCKAP1 protein, human|*Adaptor Proteins, Signal Transducing|Protein-Serine-Threonine Kinases|NIMA-Related Kinases|nucleic acid probe 1|*Oligopeptides|CXCL8 protein, human|*Interleukin-8|*Naphthalenes|HeLa Cells|CEP68 protein, human 32 CRTAC1 29953923 Neurosci. Lett. 2018 10.1016/j.neulet.2018.06.045 1 6 0 35 TNFSF13B protein, human|*B-Cell Activating Factor|*Chondroitin Sulfate Proteoglycans|MAG protein, human|Myelin-Associated Glycoprotein|Nogo Receptor 1|RTN4 protein, human|Nogo Proteins|Myelin Proteins|Growth Cones|Axons|*Signal Transduction|Neurons|Central Nervous System|Receptors, Cell Surface|Oligodendrocyte-Myelin Glycoprotein|GPI-Linked Proteins|Cells, Cultured 27 CRTAC1 29454354 J Neuroinflammation 2018 PMC5816545 10.1186/s12974-018-1084-x 1 3 0 35 Humans|*Nogo Receptor 1|*Olfactory Bulb|Nogo Proteins|Growth Cones|Calcium-Binding Proteins|Cells, Cultured|Multiple Sclerosis|Signal Transduction 27 CRTAC1 29440387 J. Neurosci. 2018 PMC6705898 10.1523/JNEUROSCI.0953-17.2018 0 10 0 35 *Nogo Receptor 1|*Receptor, Nerve Growth Factor|Myelin Proteins|*Signal Transduction|Nogo Proteins|Growth Cones|Neurites|Neurons|Receptors, Nerve Growth Factor|Myelin-Associated Glycoprotein|Calcium-Binding Proteins|Cells, Cultured|GPI-Linked Proteins|Protein Binding 27 CRYBB2 30450742 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40524 1 0 0 149 Humans|Child|*High-Throughput Nucleotide Sequencing|*Cataract|*Mutations|Crystallin|DNA Mutational Analysis|Pedigree|Connexins|Eye Proteins|Genetic Association Studies|Phenotype|Asian Continental Ancestry Group 99 CRYBB2 30364188 Int J Ophthalmol 2018 PMC6192965 10.18240/ijo.2018.10.01 0 0 0 149 Humans|beta-Crystallin B Chain|DNA Mutational Analysis|Pedigree|Cataract|Phenotypes|Haplotypes|Mutation|Asian Continental Ancestry Group|Amino Acid Sequence 99 CRYBB2 30340470 BMC Med. Genet. 2018 PMC6194747 10.1186/s12881-018-0695-5 2 0 0 149 Child|Humans|*Microphthalmos|*Cataract|Crystallins|*Chinese|Pedigree|Genes, Dominant|Heterozygote|Base Sequence|Mutation, Missense|Mutation|CRYAA protein, human 99 CRYBB2 30291584 Mol. Neurobiol. 2018 10.1007/s12035-018-1365-5 4 0 0 149 Animals|Mice|*Endophenotypes|beta-Crystallin B Chain|*Mutations|Cataracts|Lens, Crystalline|Alleles|Crystallin|*Schizophrenia|Amino Acid Sequence 99 CRYBB2 30268497 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.09.049 2 1 0 149 *Fibroblast Growth Factor 1|*Antagomirs|beta-crystallin B2|*beta-Crystallin B Chain|*Cataract|Lens, Crystalline|*Upregulation|MicroRNAs|Crystallin|*Disease Progression|*Transcriptional Activation|Apoptosis|Epithelial Cells 99 CRYBB2 29864422 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.05.195 2 0 0 149 Animals|Mice|beta-Crystallin B Chain|Cataract|Lens, Crystalline|Phenotype|Mutations|Pedigree|Amino Acid Sequence|Neurogenesis|Hippocampus|Dendrites 99 CRYBB2 29725372 Exp Ther Med 2018 PMC5920316 10.3892/etm.2018.5949 0 1 0 149 Animals|Mice|*Crystallin|*RNA, Long Noncoding|*Mice, Knockout|beta-Crystallin B Chain|Cataracts|Lens, Crystalline|mRNA|Gene Chip|Mutation|Klk1b22 protein, mouse|Kallikreins 99 CRYBB2 29395391 J. Formos. Med. Assoc. 2018 10.1016/j.jfma.2018.01.005 0 0 0 149 Humans|beta-Crystallin B Chain|Cerulean cataract|*Cataract|Cataract, Autosomal Dominant|*Mutation|Genes, Dominant|DNA Mutational Analysis|Pedigree|*Asian Continental Ancestry Group|Lod Score|Exons|Genetic Linkage|Genotype|Base Sequence|Amino Acid Sequence 99 CRYBB2 29386872 Mol. Vis. 2018 PMC5757854 0 0 0 149 Humans|*Cataract|gamma-Crystallins|*Mutations|DNA Mutational Analysis|Chinese|Pedigree|*Eye|Connexins|Phenotypes|Base Sequence|Amino Acid Sequence|Sequence Analysis, DNA 99 CRYBB3 29934435 Cancer Res. 2018 PMC6095725 10.1158/0008-5472.CAN-18-0988 5 5 0 14 *RNA, Long Noncoding|*Actins|*Cytokinesis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Cycle Checkpoints|Cell Line, Tumor|Signal Transduction|Filaments, Actin 36 CRYGC 30450742 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40524 1 0 0 132 Humans|Child|*High-Throughput Nucleotide Sequencing|*Cataract|*Mutations|Crystallin|DNA Mutational Analysis|Pedigree|Connexins|Eye Proteins|Genetic Association Studies|Phenotype|Asian Continental Ancestry Group 65 CRYGC 30340470 BMC Med. Genet. 2018 PMC6194747 10.1186/s12881-018-0695-5 2 0 0 132 Child|Humans|*Microphthalmos|*Cataract|Crystallins|*Chinese|Pedigree|Genes, Dominant|Heterozygote|Base Sequence|Mutation, Missense|Mutation|CRYAA protein, human 65 CRYGC 29914532 Orphanet J Rare Dis 2018 PMC6006596 10.1186/s13023-018-0828-0 6 0 0 132 Child|Humans|*Cataract|Crystallins|*Chinese|DNA Mutational Analysis|Pedigree|Mutation, Missense|Mutation 65 CRYGC 29774067 Theranostics 2018 PMC5957001 10.7150/thno.23624 1 21 0 132 65 CRYGC 29386872 Mol. Vis. 2018 PMC5757854 0 0 0 132 Humans|*Cataract|gamma-Crystallins|*Mutations|DNA Mutational Analysis|Chinese|Pedigree|*Eye|Connexins|Phenotypes|Base Sequence|Amino Acid Sequence|Sequence Analysis, DNA 65 CRYGD 30475834 PLoS ONE 2018 PMC6261105 10.1371/journal.pone.0207540 1 0 0 30 Humans|Mice|Animals|*Crystallin|*Zebrafish|Cataract, Autosomal Dominant|*Cataract|Lens, Crystalline|alpha-Crystallin A Chain|Animals, Genetically Modified|Disease Models, Animal|Mutation|Heat-Shock Proteins, Small|Proteins|Phenotype 154 CRYGD 30446601 J. Biol. Chem. 2018 PMC6240857 10.1074/jbc.H118.006240 1 0 0 30 *Lens, Crystalline|gamma-Crystallins|Cataract|*Redox|Amino Acid Substitution|Disulfides|*Lenses|Cysteine 154 CRYGD 30251679 Biochim Biophys Acta Mol Basis Dis 2018 PMC6590075 10.1016/j.bbadis.2018.08.021 4 1 0 30 Humans|Mice|Animals|*Cysteine|*Dimerization|gamma-Crystallins|Cataract, Age-Related Nuclear|Cataract|Lens, Crystalline|*Oxidation-Reduction|Disulfides|Glutathione|Amino Acid Substitution|Protein Domains|Aging|Mutation|Oxidative Stress 154 CRYGD 30242128 J. Biol. Chem. 2018 PMC6240864 10.1074/jbc.RA118.004551 8 0 0 30 Humans|*Lens, Eye|*Cataract|gamma-Crystallins|*Disulfides|Protein Folding|Amino Acid Substitution|Mutations 154 CRYGD 30064223 Biochemistry 2018 10.1021/acs.biochem.8b00436 3 1 0 30 Humans|*Histidine|gamma-Crystallins|*Cataract|Lens, Crystalline|Protein Multimerization|Mutagenesis, Site-Directed|Amino Acid Substitution|Models, Molecular|*Metals|Zinc|Mutation|Ions 154 CRYGD 29949747 Int. J. Biol. Macromol. 2018 10.1016/j.ijbiomac.2018.06.108 1 0 0 30 Humans|Adolescent|gamma-Crystallins|Lens, Eye|Cataract|*Glycosylation|Protein Folding|Protein Denaturation|Glycation End Products, Advanced|Diabetes Mellitus 154 CRYGD 29914532 Orphanet J Rare Dis 2018 PMC6006596 10.1186/s13023-018-0828-0 6 0 0 30 Child|Humans|*Cataract|Crystallins|*Chinese|DNA Mutational Analysis|Pedigree|Mutation, Missense|Mutation 154 CRYGD 29652984 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2018 10.3760/cma.j.issn.1003-9406.2018.02.004 2 0 0 30 Humans|gamma-Crystallins|*Cataract|*Chinese|Pedigree|Genes, Dominant|DNA Mutational Analysis|Genetic Linkage|Mutation, Missense|Base Sequence 154 CRYGD 29532225 Mol. Cell. Biochem. 2018 10.1007/s11010-018-3342-8 0 0 0 30 Animals|Humans|*Molecular Dynamics Simulation|gamma-Crystallins|Cataract, Crystalline Aculeiform|*Cataract|Lens, Crystalline|*Mutation|Mutant Proteins|Amino Acid Substitution|Hydrophobicity|Solubility 154 Csde1 30589899 PLoS ONE 2018 PMC6307745 10.1371/journal.pone.0209856 0 1 0 287 Humans|Dogs|Animals|*Caveolae|HeLa Cells|*Biotinylation|Caveolin 1|Adaptor Proteins, Signal Transducing|Carrier Proteins|siRNA|Membrane Proteins|MDCK Cells|CSDE1 protein, human|DNA-Binding Proteins|RNA-Binding Proteins 66 Csde1 30266104 Chin. Med. Sci. J. 2018 10.24920/11815 1 2 0 287 Humans|ribosomal protein L9|*Glioma|*Cell Migration|*Ribosomal Proteins|Brain Neoplasms|Cell Proliferation|3' Untranslated Region|Downregulation|Gene Expression Regulation, Neoplastic|MicroRNAs|mRNA|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Up-Regulation|TYRP1 protein, human|*Membrane Glycoproteins|siRNA|Apoptosis 66 Csde1 30247708 Nucleic Acids Res. 2018 PMC6265466 10.1093/nar/gky860 3 1 0 287 Humans|Animals|Mice|*Ribonucleoprotein|Proteomics|Long Non-Coding RNA|Protein Binding|HeLa Cells|MCF-7 Cells|Cell Line, Tumor|Cell Nucleus|CSDE1 protein, human|DNA-Binding Proteins|RNA-Binding Proteins 66 Csde1 30138317 PLoS ONE 2018 PMC6107111 10.1371/journal.pone.0201690 1 47 0 287 RNA Binding Protein|mRNA|Gene Expression Regulation|mRNA Translation|Erythroblasts|GATA1 protein, human|GATA1 Transcription Factor|Erythropoiesis|Transcriptional Activation|Ribosome|RNA, Small Interfering|Upregulation 66 Csde1 30087616 Front Physiol 2018 PMC6066521 10.3389/fphys.2018.00910 3 68 0 287 *Erythropoiesis|5' UTR|*RNA-Binding Proteins|3' Untranslated Regions|Peptide Chain Initiation, Translational|mRNA|Protein Biosynthesis|Open Reading Frames|Erythroblasts|Cell Line|Binding Sites 66 Csde1 29802697 Asian Pac. 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Cancer Prev. 2018 PMC6031819 10.22034/APJCP.2018.19.5.1343 5 10 0 287 *Carcinoma, Squamous Cell|*Mouth Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|DNA Methylation|Cell Transformation, Neoplastic|Promoter Regions, Genetic|Carcinogenesis|Downregulation|Up-Regulation|*Oxidative Stress 66 Csde1 29634759 PLoS ONE 2018 PMC5892948 10.1371/journal.pone.0193790 4 42 0 287 *EIF-2|*Phosphorylation|*Ribosome|Protein Biosynthesis|Open Reading Frames|RNA, Messenger|Gene Expression Regulation|Base Sequence|Stress, Physiological|DNA-Binding Proteins 66 Csde1 29545014 Virus Res. 2018 10.1016/j.virusres.2018.03.006 3 0 0 287 Humans|*Encephalitis Viruses, Tick-Borne|*3' Untranslated Region|HEK293 Cells|Encephalitis, Tick-Borne|RNA, Viral|Genome, Viral|Nucleic Acid Conformation|*Genomics|Virus Replication|Virulence|CSDE1 protein, human|DNA-Binding Proteins|RNA-Binding Proteins 66 Csde1 29504908 BMC Med Genomics 2018 PMC5836820 10.1186/s12920-018-0327-0 2 7 0 287 *Carotid Body Tumor|*Exome|Paragangliomas|Succinate Dehydrogenase|Germ-Line Mutation|Genetic Predisposition to Disease|Mutation|Head and Neck Neoplasms 66 Csde1 29453919 Endocr Regul 2018 10.2478/enr-2018-0006 6 0 0 287 *Pheochromocytoma|Prospective Studies|*Adrenal Gland Neoplasms|Paragangliomas|*Epigenesis, Genetic|Mutation|Mutations, Germline|Biomarkers, Tumor|endothelial PAS domain-containing protein 1|Basic Helix-Loop-Helix Transcription Factors 66 Csde1 29422612 Sci Rep 2018 PMC5805679 10.1038/s41598-018-20518-7 5 33 0 287 *Proteostasis|*Cell, Erythroid|RNA Binding Protein|Erythropoiesis|Erythroblasts|Anemia, Diamond-Blackfan|*Cell Line|DNA-Binding Proteins|Cell Differentiation|RNA, Messenger|Gene Expression Regulation|Gene Knockdown Techniques 66 Csde1 29395067 Mol. Cell 2018 10.1016/j.molcel.2017.12.020 76 0 0 287 Humans|*mRNA|Cytoplasmic Granules|Cytoplasm|RNA-Binding Proteins|RNA|Carrier Proteins|Stress, Physiological|HeLa Cells|CSDE1 protein, human|DNA-Binding Proteins|Ubap2L protein, human 66 CSMD1 30545040 Int J Mol Sci 2018 PMC6321139 10.3390/ijms19123996 4 0 0 70 *Squamous Cell Carcinoma of Head and Neck|Head and Neck Cancer|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Transcriptome|Mutation|Membrane Proteins 142 CSMD2 30453668 J Clin Med 2018 PMC6262537 10.3390/jcm7110446 0 0 0 9 20 CSMD3 30391781 Cancer Lett. 2018 10.1016/j.canlet.2018.10.035 0 0 0 6 41 CSMD3 29731991 Oncotarget 2018 PMC5929434 10.18632/oncotarget.24924 2 0 0 6 41 CSMD3 29668032 J. Orthop. Res. 2018 10.1002/jor.24025 1 0 0 6 41 CSMD3 29575536 Genes Chromosomes Cancer 2018 PMC5951744 10.1002/gcc.22539 12 2 0 6 Humans|*Adenomas|*DNA Mutational Analysis|*Carcinomas|*Colon|Genes, APC|Colon Cancer|Mutations|Colorectal Cancer|Whole Exome Sequencings|Carcinogenesis|Disease Progression|Base Sequence|BRD9 protein, human|Transcription Factors 41 CST7 30340518 Acta Neuropathol Commun 2018 PMC6194687 10.1186/s40478-018-0612-3 8 0 0 128 Animals|Mice|Humans|*Alzheimer Disease|*Microglia|Presenilin-1|Amyloid beta-Peptides|Amyloid beta-Protein Precursor|Mice, Transgenic|Amyloid Plaques|TREM2 protein, human|Receptors, Immunologic|Membrane Glycoproteins|Peptide Fragments|Brain|*Macrophages|Astrocytes|Glial Fibrillary Acidic Protein|Disease Models, Animal|Gene Expression Regulation|Up-Regulation 39 CST7 30302405 Biochem Biophys Rep 2018 PMC6174832 10.1016/j.bbrep.2018.09.007 1 5 0 128 Mice|Animals|Humans|*Spleen|*Interleukin-4|*B Cells|STAT6 protein, human|STAT6 Transcription Factor|Signal Transduction|Suppressor of Cytokine Signaling Proteins|Cytokines|Oligonucleotide Array Sequence Analysis|CDH1 protein, human|Antigens, CD|Cells, Cultured|Blotting, Western|Inflammation|RNA, Messenger|Cadherins|PMEPA1 protein, human|Membrane Proteins 39 CST7 30283032 Mol. Psychiatry 2018 PMC6494440 10.1038/s41380-018-0255-6 6 1 0 128 Animals|Mice|*Alzheimer Disease|*Pathology, Molecular|Plaque, Amyloid|*Amyloidosis|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|tau Proteins|Mice, Transgenic|Microglia|Disease Models, Animal|*Phenotype|TREM2 protein, human|Membrane Glycoproteins|Receptors, Immunologic|Brain|*Complement 39 CST7 30112561 Sheng Li Xue Bao 2018 1 0 0 128 *Computational Biology|*Depressive Disorder, Major|Protein Interaction Network|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Gene Annotation|Gene Expression Regulation, Neoplastic 39 CST7 30033148 Eur. J. Cell Biol. 2018 10.1016/j.ejcb.2018.07.002 3 0 0 128 Humans|*Monocytes|*Macrophages|*Cell Differentiation|Cystatins|U937 Cells|Limulus clotting factor C|*Arthropod Proteins|*Serine Endopeptidases|Cathepsins|HL-60 Cells|Hematopoiesis|CCAAT-Enhancer-Binding Proteins|Cathepsin C|*Leukocyte Count|Upregulation|Lysosomes|Endosomes 39 CST7 29946151 Nat Commun 2018 PMC6018668 10.1038/s41467-018-04908-z 14 11 0 128 Animals|Pregnancy|*T-Lymphocytes, Regulatory|*Myocytes, Cardiac|*Myocardial Infarction|Myocardium|Medium, Conditioned|Cell Proliferation|Cells, Cultured 39 CST7 29335477 Sci Rep 2018 PMC5768803 10.1038/s41598-017-17735-x 11 0 0 128 *Immunity, Humoral|*Transcriptome|*Influenza, Human|Leukocytes, Mononuclear|*Seasons|Influenza Vaccine|*Vaccination|Cellular Immunity|Influenza A Virus, H1N1 Subtype|Hemagglutination Inhibition Tests|B Cells|Antibodies, Viral|*Clustering 39 CST8 30362892 Per Med 2018 10.2217/pme-2018-0049 0 0 0 190 Humans|Male|*Urinary Bladder Neoplasms|*Testis|Antigens, Neoplasm|Biomarkers, Tumor|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|RNA, Messenger|KIF2B protein, human|Kinesin 31 CTAGE1 29305299 Exp. Eye Res. 2018 10.1016/j.exer.2017.12.012 3 0 0 3 Humans|Mice|Animals|Adult|Peters anomaly|NECTIN1 protein, human|*Nectins|*Ectopia Lentis|Genome-Wide Association Study|*Corneal Opacity|*Eye Abnormalities|*Anterior Eye Segment|Lens, Crystalline|Corneal Disease|Phenotype|Mutation|Diabetes Mellitus, Type 2 238 CTNND2 30458179 Exp. Cell Res. 2018 10.1016/j.yexcr.2018.11.011 2 2 0 439 Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Wnt Signaling Pathway|*Catenins|beta Catenin|*Disease Progression|Hep G2 Cells|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Upregulation|*Hypoxia|Cell Line, Tumor|Cell Transformation, Neoplastic 84 CTNND2 30167661 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.17-224685 0 2 0 439 Guinea Pigs|Animals|*Sclera|*Myopia|*Cyclic AMP|Sensory Deprivation|*Microarray Analysis|RNA, Messenger|Forskolin|Disease Models, Animal|Real-Time Polymerase Chain Reaction|Adenosine Monophosphate 84 CUX2 30427350 Dalton Trans 2018 10.1039/c8dt03210f 0 1 0 88 *Bromides|*Copper|*Chlorides|*Reagents|Structures, Molecular|*Catalysis|Ligands|Crystallography, Xray|Models, Molecular 128 CUX2 30378610 Dalton Trans 2018 10.1039/c8dt03072c 0 0 0 88 *Copper|Structures, Molecular|Organometallic Compounds|Heterocyclic Compounds|Crystallography, X-Ray|Models, Molecular|Chlorides 128 CUX2 30329130 Nucleic Acids Res. 2018 PMC6326801 10.1093/nar/gky953 4 4 0 88 Mice|Animals|*Neurons|Neurogenesis|Transcription Factors|DNA-Binding Proteins|Cerebral Cortex|Cell Differentiation|Chromatin|Repressor Proteins|Histones|Histone-Lysine N-Methyltransferase|Nerve Tissue Proteins|Transcription, Genetic|Gene Expression Regulation, Developmental|Methylation|Cell Cycle|Cell Proliferation|Dot1l protein, mouse|Cenpj protein, mouse 128 CUX2 30281874 Cancer Sci. 2018 PMC6272082 10.1111/cas.13815 4 1 0 88 Humans|*Genome-Wide Association Study|*Stomach Neoplasms|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Helicobacter Infections|Asian Continental Ancestry Group|Case-Control Studies|Genotype|Odds Ratio|Risk Factors|Japan 128 CUX2 30123371 Open Rheumatol J 2018 PMC6062909 10.2174/1874312901812010094 1 0 0 88 *Transporters, Membrane|*Gout|Hyperuricemia|Uric Acid|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|*Regulatory Genes|Case-Control Studies|*Reproductive History 128 CUX2 29795476 Eur. J. Hum. Genet. 2018 PMC6117349 10.1038/s41431-018-0184-5 0 0 0 88 Humans|*Intellectual Disability|*Autism Spectrum Disorder|*Seizures|Epilepsies, Myoclonic|Epilepsy|Infantile Autism|Mutation, Missense|*Databases, Genetic|Sequencing, Whole Exome|Phenotype|Genetic Predisposition to Disease 128 CUX2 29630738 Ann. Neurol. 2018 PMC6021218 10.1002/ana.25222 2 0 0 88 *Epilepsy|Epilepsies, Myoclonic|Seizures|Epilepsy, Generalized|Electroencephalography|Phenotype|DNA-Binding Proteins|Mutation|Transcription Factor 128 CUX2 29518378 Brain Res. 2018 10.1016/j.brainres.2018.02.044 0 0 0 88 Autism Spectrum Disorder|*Neurons|Transcription Factors|Homeodomain Proteins|Repressor Proteins|Cerebral Cortex|Nuclear Proteins|Neurogenesis|Gene Expression Regulation, Developmental|Pyramidal Neurons 128 CUZD1 29590158 PLoS ONE 2018 PMC5874003 10.1371/journal.pone.0194166 3 0 0 24 Humans|*Colitis, Ulcerative|*Prospective Studies|Crohn Disease|*Biomarkers|*Cohort Studies|*Disease Progression|Autoantibodies|Immunoglobulin A|GPI-Linked Proteins|Immunoglobulin G|Prognosis 35 CUZD1 29321207 J. Biol. Chem. 2018 PMC5827451 10.1074/jbc.RA117.000162 3 7 0 24 Mice|Animals|*Zona Pellucida|STAT5A protein, human|STAT5 Transcription Factor|*Epithelium|Mammary Glands, Animal|Prolactin|Cells, Epithelial|Receptors, Prolactin|Signal Transduction|Phosphorylation|Epidermal Growth Factor|Cell Proliferation|Janus Kinase 2|Cell Differentiation|Tumor Suppressor Proteins|DNA-Binding Proteins|Trans-Activators|Cell Line 35 CYP4X1 30532780 J Oncol 2018 PMC6250001 10.1155/2018/6301980 1 0 0 8 *Carcinoma, Squamous Cell|*Arachidonic Acid|*Epoprostenol|*Mouth Neoplasms|prostacyclin synthetase|*Cytochrome P450|*Intramolecular Oxidoreductases|Gene Expression Regulation, Neoplastic|Cytochrome P450 Family 2|Gene Expression Regulation, Enzymologic|RNA, Messenger 26 CYP4X1 30032116 J. Neurol. Neurosurg. Psychiatry 2018 10.1136/jnnp-2018-318756 3 0 0 8 *Age of Onset|Creutzfeldt-Jakob Disease, Sporadic|*Creutzfeldt-Jakob Syndrome|Prions|Prion Proteins|Codon|Pedigree|Genotype|Mutation 26 CYP4X1 29437915 J. Pharmacol. Exp. Ther. 2018 10.1124/jpet.117.247130 0 1 0 8 Humans|cytochrome P-450 4X1|Leukocytes, Mononuclear|*Glioma|STAT3 protein, human|*STAT3 Transcription Factor|*Cytochrome P-450 Enzyme System|*Macrophages|*Flavonoids|Neovascularization, Pathologic|Brain Neoplasms|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Cell Movement|Cell Line, Tumor|Cell Proliferation|ErbB Receptors|EGFR protein, human 26 CYTL1 30582450 Circ. Res. 2018 10.1161/CIRCRESAHA.118.313645 1 0 0 57 Humans|Animals|*Endothelial Progenitor Cells|Neovascularization, Physiologic|Angiogenic Proteins|Ischemia|Hindlimb|Human Umbilical Vein Endothelial Cells|Cell Movement|Cell Proliferation|Signal Transduction|Cells, Cultured|Cytokines 34 CYTL1 30342560 Clin Epigenetics 2018 PMC6196025 10.1186/s13148-018-0558-0 11 0 0 57 *DNA Methylation|CpG Islands|*Smoking, Tobacco|*Smoking|Epigenesis, Genetic|*Gene Expression|Cytochrome P-450 CYP1A1|Basic Helix-Loop-Helix Transcription Factors|*Adipose Tissue|Gene Expression Profiling|Repressor Proteins|*Biochemical Phenomena|Case-Control Studies 34 CYTL1 29901552 J. Pediatr. Gastroenterol. Nutr. 2018 10.1097/MPG.0000000000002057 1 0 0 57 Child|Humans|*Quality of Life|IGF1 protein, human|*Insulin-Like Growth Factor I|*Inflammatory Bowel Disease|*Fatigue|Surveys and Questionnaires|Severity of Illness Index 34 CYTL1 29672513 PLoS ONE 2018 PMC5908183 10.1371/journal.pone.0195132 2 0 0 57 Animals|*Chickens|*Sequencing, RNA|Transcriptome|*Polyunsaturated Fatty Acids|Gene Expression Profiling|Meat|Networks, Gene|Acids, Fatty|Muscle, Skeletal|*Whole Exome Sequencing|High-Throughput Nucleotide Sequencing|mRNA|Quantitative Trait Loci|Gene Ontology|Lipid Metabolism 34 DACH2 30429477 Nat Commun 2018 PMC6235880 10.1038/s41467-018-07041-z 10 0 0 37 Phosphatidylinositol 3-Kinases|*Colorectal Cancer|Liver Neoplasms|Adenocarcinoma|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Adaptor Proteins, Signal Transducing|*Sequencing, Whole Genome|Signal Transduction|Mutations 36 DACH2 29789566 Cell Death Dis 2018 PMC5964117 10.1038/s41419-018-0671-1 2 1 0 37 Adult|Male|Humans|*Leydig Cells|*Testis|Sexual Maturation|Klinefelter Syndrome|Spermatogenesis|Sertoli Cells|*Transcriptome Analysis|Sertoli Cell-Only Syndrome|Germ Cells|*Cell Differentiation|Sex Chromosome Aberrations|Transcriptomes 36 DACH2 29671242 Mol. Biol. Rep. 2018 10.1007/s11033-018-4185-9 0 0 0 37 *Myogenin|*Muscle Atrophy|SKP Cullin F-Box Protein Ligases|Tripartite Motif Proteins|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|Muscle Proteins|Ubiquitin Ligase E3|Cachexia|Muscle, Skeletal|Muscle Fibers, Skeletal|Dexamethasone|Up-Regulation 36 DACT2 30542447 Exp Ther Med 2018 PMC6257741 10.3892/etm.2018.6771 0 10 0 129 Humans|*Stomach Neoplasms|Neoplasm Invasiveness|Cell Proliferation|MicroRNAs|Cell Movement|Gene Expression Regulation, Neoplastic|*Stomach|Apoptosis|mRNA|Cell Line, Tumor|Adenocarcinoma|Western Blotting|DACT2 protein, human|Carrier Proteins|Neoplasm Proteins|MIRN214 microRNA, human 53 DACT2 30450639 J. Orthop. Res. 2018 10.1002/jor.24178 4 0 0 129 Humans|Dogs|Animals|*Hip Dysplasia, Canine|Epithelial-Mesenchymal Transition|Hedgehog Proteins|*Hip|Hip Osteoarthritis|Hip Dislocation, Congenital|Hip Joint|*Gene Expression|HHIP protein, human|*Membrane Glycoproteins|Dog Diseases|Chromosome Mapping|Phenotype|DACT2 protein, human|Carrier Proteins|Neoplasm Proteins 53 DACT2 30401983 Oncogene 2018 PMC6430693 10.1038/s41388-018-0543-2 5 9 0 129 Humans|Child|*Retinoblastoma|SMAD2 protein, human|*Smad2 Protein|*Signal Transduction|SMAD3 protein, human|Smad3 Protein|Downregulation|Transforming Growth Factor beta|Activin Receptors, Type I|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|shRNA|mRNA|Retinal Neoplasms|DACT2 protein, human|Carrier Proteins|Neoplasm Proteins 53 DACT2 30359298 Clin Epigenetics 2018 PMC6136178 10.1186/s13148-018-0459-2 5 4 0 129 *Nasopharyngeal Carcinoma|*Nasopharyngeal Neoplasms|*Paclitaxel|*Apoptosis|*Cell Line, Tumor|*G2 Phase Cell Cycle Checkpoints|*Genes, Tumor Suppressor|CTNNB1 protein, human|beta Catenin|*Nasopharynx|Carcinomas|DNA Methylation|Neoplasm Proteins|Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|*Catenins|Epigenesis, Genetic|Promoter Regions, Genetic 53 DACT2 30075814 Clin Epigenetics 2018 PMC6091063 10.1186/s13148-018-0535-7 0 9 0 129 *Nasopharyngeal Carcinoma|*Wnt Signaling Pathway|DNA Methylation|*Catenins|beta Catenin|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Nasopharyngeal Neoplasms|Cell Line, Tumor|Down-Regulation|Cell Movement|Cell Proliferation|Promoter Regions, Genetic|Carcinoma 53 DACT2 29745077 J BUON 2018 1 1 0 129 *DNA Methylation|*Promoter Regions, Genetic|CpG Islands|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Gene Silencing|Biomarkers, Tumor|Cell Line, Tumor|Carrier Proteins|Cell Proliferation 53 DACT2 29456669 Exp Ther Med 2018 PMC5795574 10.3892/etm.2018.5706 0 11 0 129 Child|Humans|Wnt Signaling Pathway|Adaptor Proteins, Signal Transducing|beta Catenin|Nuclear Proteins|Cell Proliferation|*Asthma|IL5 protein, human|Interleukin-5|Upregulation|Transcriptional Activation|mRNA|DACT2 protein, human|Carrier Proteins|Neoplasm Proteins|DACT1 protein, human 53 DACT2 29435071 Oncol Lett 2018 PMC5778863 10.3892/ol.2017.7633 1 0 0 129 Humans|*Wnt Signaling Pathway|DNA Methylation|Neoplasm Proteins|Promoter Regions, Genetic|Carrier Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Genes, Tumor Suppressor|Gene Silencing|*Disease Progression|DACT2 protein, human 53 DAOA 30459659 Front Psychiatry 2018 PMC6232512 10.3389/fpsyt.2018.00566 4 0 0 34 Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Schizophrenia|D-Amino-Acid Oxidase|Gene Frequency|Carrier Proteins|Intracellular Signaling Peptides and Proteins 168 DAOA 30037290 Free Radic. Res. 2018 10.1080/10715762.2018.1504293 1 3 0 34 Humans|*Superoxide Dismutase-1|*Superoxides|*Superoxide Dismutase|Schizophrenia|D-Amino-Acid Oxidase|Reactive Oxygen Species|Mitochondria|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Cell Line|SOD1 protein, human 168 DAOA 29797699 Mol Nutr Food Res 2018 10.1002/mnfr.201800193 3 0 0 34 Humans|*DNA Methylation|*Stilbenoids|CpG Islands|Genome, Human|Genome-Wide Association Study|*Diet|Cell Line, Tumor 168 DAOA 29326614 Front Psychiatry 2018 PMC5742321 10.3389/fpsyt.2017.00292 4 4 0 34 Humans|*Psychosis|*Schizophrenia|DAO protein, human|D-Amino-Acid Oxidase|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Haplotypes|Genotype|Neuregulin-1|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Case-Control Studies 168 DAZ1 30050315 Appl Clin Genet 2018 PMC6055888 10.2147/TACG.S158297 0 0 0 63 Humans|Male|*Azoospermia|Egypt|Oligospermia|Infertility, Male|Chromosomes, Human, Y|Chromosome Deletion|Gene Deletion|Polymerase Chain Reaction|DAZL protein, human|RNA-Binding Proteins 205 DBR1 30123775 Front Cell Infect Microbiol 2018 PMC6085484 10.3389/fcimb.2018.00255 0 0 0 69 Animals|*Introns|*Parasites|RNA Splicing|Spliceosomes|RNA, Messenger|Entamoeba histolytica 63 DBR1 30023353 Front Cell Infect Microbiol 2018 PMC6039765 10.3389/fcimb.2018.00228 0 4 0 69 lariat debranching enzyme|RNA Nucleotidyltransferases|RNA Splicing|Intron|RNA|Entamoeba histolytica|HIV-1 63 DBR1 29743047 BMC Biotechnol. 2018 PMC5944158 10.1186/s12896-018-0438-x 0 0 0 69 *Norisoprenoids|*Reductase|Fragrance|Cloning, Molecular 63 DBR1 29495353 Genes (Basel) 2018 PMC5867839 10.3390/genes9030118 8 1 0 69 *circRNA|*Cryptococcus neoformans|*DNA, Fungal|MicroRNAs|Gene Expression Profiling|Gene Regulatory Networks 63 DBR1 29474921 Cell 2018 PMC5886375 10.1016/j.cell.2018.02.019 20 0 0 69 Child|Humans|lariat debranching enzyme|RNA Nucleotidyltransferases|Introns|RNA Splicing|RNA|RNA Precursors|Saccharomyces cerevisiae|Amino Acid Sequence|Mutations|Alleles|*Brainstem|Infections 63 DCHS1 30285776 J Transl Med 2018 PMC6167794 10.1186/s12967-018-1642-0 3 0 0 39 Papillary Thyroid Microcarcinoma|*Cell Adhesion|*Carcinoma, Papillary|*Thyroid Neoplasms|Proto-Oncogene Proteins B-raf|Mutation|Lymphatic Metastasis|Adenocarcinoma 40 DCHS1 29681106 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.38652 2 2 0 39 Humans|Female|Van Maldergem Wetzburger Verloes syndrome|*Intellectual Disability|*Hand Deformities, Congenital|*Foot Deformities, Congenital|*Craniofacial Abnormalities|*Abnormalities, Multiple|*Joint Instability|*Phenotypes|*Alleles|*Syndrome|Cadherins|ADAMTS3 protein, human|ADAMTS Proteins|Procollagen N-Endopeptidase|DCHS1 protein, human|CCBE1 protein, human|Calcium-Binding Proteins|Tumor Suppressor Proteins 40 DCHS1 29593499 Front Cell Neurosci 2018 PMC5857600 10.3389/fncel.2018.00057 3 24 0 39 Periventricular Nodular Heterotopia|*Neurogenesis|*Cell Movement|Neurons|Filamins|Brain|Signal Transduction 40 DCHS1 29352010 Heart 2018 PMC6168077 10.1136/heartjnl-2017-312420 3 1 0 39 Humans|*Mitral Valve Prolapse|Mechanotransduction, Cellular|Mitral Valve|Pedigree|Phenotype|Marfan Syndrome|Echocardiography|Genetic Predisposition to Disease|Diastole 40 dd3 30576938 Int. J. Drug Policy 2018 10.1016/j.drugpo.2018.12.008 0 0 0 474 Humans|Community Pharmacy Services|Therapy, Opioid Substitution|*Primary Care|Pharmacists|Hepatitis C|Patient Preference 125 dd3 30573416 Res Social Adm Pharm 2018 10.1016/j.sapharm.2018.12.005 0 0 0 474 Humans|*Pharmacists|*Translations|*Survey|Professional Role|Attitude of Health Personnel|Cross-Sectional Studies 125 dd3 30336232 Resuscitation 2018 10.1016/j.resuscitation.2018.10.010 1 0 0 474 Child|Humans|*Cohort Studies|*Early Warning Score|Clinical Deterioration|Critical Illness|Intensive Care Units, Pediatric|Retrospective Studies|ROC Curve|Emergency Service, Hospital|*Hospital|Severity of Illness Index|Scotland 125 dd3 30185651 Sci Transl Med 2018 10.1126/scitranslmed.aao2966 3 0 0 474 Adult|Female|Humans|Genome-Wide Association Study|Receptors, Antigen, T-Cell, alpha-beta|Receptors, Antigen, T-Cell, gamma-delta|T Cells|Cell Differentiation 125 dd3 30125973 J. Cell. Biochem. 2018 10.1002/jcb.27304 3 1 0 474 *Dapsone|*Leprostatic Agents|*Molecular Docking Simulation|*Drug Therapy, Combination|Mycobacterium leprae|Leprosy|Dihydropteroate Synthase|Amino Acid Sequence|Mutation 125 dd3 29960599 BMC Fam Pract 2018 PMC6026505 10.1186/s12875-018-0794-6 0 0 0 474 Humans|Occult Blood|*Screening|*Primary Care|Early Detection of Cancer|Colorectal Neoplasms|Patient Acceptance of Health Care|Health Knowledge, Attitudes, Practice|*Intestines 125 dd3 29533050 Swiss Dent J 2018 0 2 0 474 Cattle|Animals|*Dentifrices|*Diamond|Tooth Abrasion|Toothbrushing|Tooth Erosion|Toothpastes|Dentin|Olaflur|Fluorides|Silica|Diamines 125 DDX60 29879868 Technol. Cancer Res. Treat. 2018 PMC6009088 10.1177/1533033818780088 3 0 0 64 Mice|Animals|*Up-Regulation|*Plasmids|Electroporation|*B16 Melanoma|Transfections|*DNA|Gene Transfer Techniques|Genetic Therapy|*Spheroid, Cellular|Angiogenesis Inhibitors|*Transcriptional Activation 35 DDX60 29721152 Oncotarget 2018 PMC5922346 10.18632/oncotarget.24816 3 0 0 64 Mice|Animals|*Cytosol|*Up-Regulation|*Plasmids|*DNA|Electroporation|Receptors, Pattern Recognition|*Transcriptional Activation|*B-Lymphocytes|Cytokines|Gene Therapy|Immunity, Innate|Signal Transduction|mRNA|Real Time Polymerase Chain Reaction|Cell Death 35 DDX60 29321042 Arthritis Res. Ther. 2018 PMC5763828 10.1186/s13075-017-1501-z 2 14 0 64 Humans|Child|*RNA|*Lupus Erythematosus, Systemic|Interferon Type I|Toll-Like Receptor 7|Sjogren's Syndrome|Monocytes|*DNA|RNA, Messenger|Gene Expression Profiling|Cohort Studies 35 DEXI 30503676 J. Pharmacol. Sci. 2018 10.1016/j.jphs.2018.11.001 11 0 0 27 *Macular Edema|*Diabetic Retinopathy|Dexamethasone|Intravitreal Injections|Drug Implants|Glucocorticoids|Visual Acuity|Angiogenesis Inhibitors|Tomography, Optical Coherence|Retreatment|*Prostheses and Implants|Diabetes Mellitus 30 DEXI 30478640 Diabetologia 2018 10.1007/s00125-018-4782-0 6 3 0 27 Rats|Humans|Animals|*Insulin-Secreting Cells|*Diabetes Mellitus, Type 1|TYRP1 protein, human|*Membrane Glycoproteins|*Signal Transduction|*Inflammation|Apoptosis|Membrane Proteins|SNPs|CLEC16A protein, human|Monosaccharide Transport Proteins|Lectins, C-Type 30 DEXI 30071827 BMC Genomics 2018 PMC6090848 10.1186/s12864-018-4938-9 1 0 0 27 Humans|Horses|Animals|*Quantitative Trait Loci|Genome-Wide Association Study|*Asthma|Genetic Association Studies|Polymorphism, Single Nucleotide|Horse Diseases|Airway Obstruction|Gene Expression Profiling|Phenotypes|Leukocytes, Mononuclear|*Respiration Disorders 30 DEXI 29904099 Genes Immun. 2018 PMC6286696 10.1038/s41435-018-0034-z 4 0 0 27 *Eosinophilic Esophagitis|Genetic Predisposition to Disease|Genotype|Esophagus|Nuclear Proteins|Calpain 30 DEXI 29599613 Int J Nanomedicine 2018 PMC5866724 10.2147/IJN.S151597 1 0 0 27 dexibuprofen|*Nanocrystals|Solubility|Hypromellose Derivatives|Particle Size|Drug Liberation|Polymers|Ibuprofen|Biological Availability|Povidone|X-Ray Diffraction|Solvents|Calorimetry, Differential Scanning 30 DFNA5 30564238 Front Immunol 2018 PMC6288192 10.3389/fimmu.2018.02842 6 0 0 0 Humans|*Monocytes|*T Cells|*Necrosis|Pyroptosis|CASP3 protein, human|Caspase 3|Apoptosis|Apoptosis Regulatory Proteins|Cell Line, Tumor|Macrophages|Receptors, Estrogen|Plasma Membrane|GSDMD protein, human|Neoplasm Proteins 79 DFNA5 30091681 Tumour Biol. 2018 10.1177/1010428318793023 1 0 0 0 Humans|*Oral Cancer|*Papillomavirus Infections|*Tobacco, Smokeless|Carcinoma, Squamous Cell|Deafness, Autosomal Dominant 5|*Tobacco|Retrospective Studies|*Hearing Loss, Sensorineural|HPV 16|*Tobacco Chewing|Papillomaviridae|Human papillomavirus 18|*Smoking|DNA, Viral|India|SYK protein, human|Syk Kinase|NELL1 protein, human 79 DFNA5 30061362 Clin. Cancer Res. 2018 10.1158/1078-0432.CCR-18-1478 15 2 0 0 Humans|*Molecular Targeted Therapy|*Pyroptotic Cell Death|Apoptosis|Caspase 3|Cell Line, Tumor|Receptors, Estrogen 79 DFNA5 29849037 Sci Rep 2018 PMC5976723 10.1038/s41598-018-26554-7 2 2 0 0 Humans|Deafness, Autosomal Dominant 5|*Hearing Loss, Sensorineural|*Hearing Loss|*Deafness|Pedigree|Exon|RNA Splicing|Chinese|Heterozygote|Mutation|Genetic Linkage|Family|Receptors, Estrogen 79 DFNA5 29682089 Clin Epigenetics 2018 PMC5896072 10.1186/s13148-018-0479-y 8 2 0 0 Humans|Female|CpG Islands|Carcinoma, Ductal, Breast|DNA Methylation|Receptors, Estrogen|Prognosis|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Epigenesis, Genetic|Biomarkers, Tumor|Cell Line, Tumor|Breast Cancer 79 DFNA5 29491424 Sci Rep 2018 PMC5830643 10.1038/s41598-018-21998-3 18 45 0 0 Mice|Animals|*Inflammasomes|CASP8 protein, human|*Caspase 8|Caspase 1|Neuronal Apoptosis-Inhibitory Protein|Pyroptosis|*Macrophages|CARD Signaling Adaptor Proteins|Apoptosis Regulatory Proteins|Calcium-Binding Proteins|Legionella pneumophila|Flagellin|Apoptosis|Mice, Inbred C57BL 79 DGCR2 30425917 Balkan J. Med. Genet. 2018 PMC6231321 10.2478/bjmg-2018-0002 0 0 0 182 Child|Male|Humans|Chromosome 22q11.2 Microduplication Syndrome|Chromosome Duplication|DiGeorge Syndrome|Abnormalities, Multiple|Heart Defects, Congenital|Phenotype|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|*Family|Syndrome|Intellectual Disability|Chromosome 22 22 DGCR2 29305086 Biol. Psychiatry 2018 10.1016/j.biopsych.2017.11.015 3 0 0 182 Humans|Cell Adhesion Molecules, Neuronal|Extracellular Matrix Proteins|Serine Endopeptidases|*Schizophrenia|Nerve Tissue Proteins|Neurons|Cerebral Cortex|Cell Movement 22 DHRS2 30535463 Int. J. Oncol. 2018 10.3892/ijo.2018.4657 4 3 0 173 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|miRNA|Cell Proliferation|Carcinoma, Squamous Cell|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|RNA Interference|Cell Line, Tumor|Oncogenesis|Biomarkers, Tumor|Apoptosis 35 DHRS2 30460772 J. Cell. Mol. Med. 2018 PMC6307807 10.1111/jcmm.13971 3 1 0 173 Humans|Male|Adolescent|Young Adult|Adult|romidepsin|Testicular Germ Cell Tumor|*Neoplasms, Germ Cell and Embryonal|*Depsipeptides|*Cell Cycle Arrest|*Apoptosis|Testicular Neoplasms|Cisplatin|Histone Deacetylase Inhibitor|Cell Proliferation|Cell Line, Tumor|Acetylation|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Histone Deacetylases|Up-Regulation|DUSP1 protein, human|Dual Specificity Phosphatase 1 35 DHRS2 29783891 Future Oncol 2018 10.2217/fon-2018-0242 0 0 0 173 Humans|Female|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Prognosis|Biomarkers, Tumor|Neoplasm Grading|Kaplan-Meier Estimate 35 DHRS2 29722072 Mol. Carcinog. 2018 10.1002/mc.22824 1 1 0 173 *Osteosarcoma|Telomerase|Telomere|Telomere Lengthening|Cell Line, Tumor|*Neoplastic Processes|Apoptosis|Downregulation|Transfection 35 DHRS2 29632240 J. Cell. Sci. 2018 10.1242/jcs.210724 8 6 0 173 Humans|*Tumor Suppressor Protein p53|*Diploidy|*Cellular Senescence|Proto-Oncogene Proteins c-mdm2|*Transcription Factors|*Fibroblasts|Cyclin-Dependent Kinase Inhibitor p21|Cell Proliferation|Cell Line, Tumor|Cell Cycle|Heat Shock Transcription Factor 1|HSP70 Heat-Shock Proteins|MDM2 protein, human 35 DHRS2 29436749 Mol. Carcinog. 2018 10.1002/mc.22793 9 0 0 173 Humans|*Genes, Homeobox|*Tumor Suppressor Protein p53|*Carcinogenesis|homeobox protein HOXA13|*Homeodomain Proteins|Fluorouracil|Gastric Cancer|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Cell Line, Tumor|Antimetabolites, Antineoplastic|*Stomach|Xenograft Model Antitumor Assays|Oncogenes|Apoptosis|Signal Transduction|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2 35 DHRS2 29423105 Oncotarget 2018 PMC5790522 10.18632/oncotarget.23694 3 4 0 173 Humans|*Tamoxifen|*Transcriptome Profiling|Transcriptome|MCF-7 Cell|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Molecular Sequence Annotation|Signal Transduction 35 DHX33 30552990 Cell. Signal. 2018 10.1016/j.cellsig.2018.12.005 3 1 0 151 Humans|*Glioblastoma|*Phosphatidylinositol 3-Kinases|*RNA Helicase|MTOR protein, human|*TOR Serine-Threonine Kinases|*Protein Kinase Inhibitors|*Cell Proliferation|Brain Neoplasms|Phosphoinositide-3 Kinase Inhibitors|Cell Line, Tumor|Cell Migration|Signal Transduction|DHX33 protein, human|DEAD-box RNA Helicases 25 DHX33 29870660 Biochemistry 2018 10.1021/acs.biochem.8b00166 1 0 0 151 Humans|DEAD-box RNA Helicases|TYRP1 protein, human|Adenosine Triphosphatases|*Membrane Glycoproteins|Protein Binding|Ribosome|Binding Site|Translation, Protein|*Biochemical Phenomena|DNA|DHX33 protein, human 25 DHX33 29864424 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.05.201 1 0 0 151 Mice|Animals|*Codon, Initiator|Peptide Chain Initiation, Translational|*Reading Frames|Protein Biosynthesis|DEAD-box RNA Helicases|Codon|RNA, Messenger|Cell Proliferation|Cell Line, Tumor 25 DIS3L2 30536706 FEBS Lett. 2018 10.1002/1873-3468.13313 0 0 0 76 exoribonuclease II|*Temperature|*Exoribonucleases|Escherichia coli Proteins|Escherichia coli|RNA|Protein Binding|Models, Molecular|*Biochemical Phenomena|Kinetics|Catalysis|Mutation 76 DIS3L2 30483311 Front Genet 2018 PMC6240794 10.3389/fgene.2018.00538 3 1 0 76 Humans|UTP-RNA uridylyltransferase|U6 small nuclear RNA|RNA, Small Nuclear|RNA Nucleotidyltransferases|Ribonucleoprotein, U4-U6 Small Nuclear|RNA Splicing|Spliceosomes|MicroRNAs|Nucleotidyltransferases|Crystallography, X-Ray|Models, Molecular 76 DIS3L2 30462292 Nucleic Acids Res. 2018 PMC6344859 10.1093/nar/gky1164 1 0 0 76 Animals|*RNA|RNA Nucleotidyltransferases|RNA Processing, Post-Transcriptional|RNA Stability|Drosophila Proteins|Substrate Specificity|Drosophila|Nucleotidyltransferases|Active Site|Binding Sites|Amino Acid Sequence|Uridine Triphosphate|Crystallography, X-Ray 76 DKKL1 30476623 J Pharmacol Toxicol Methods 2018 10.1016/j.vascn.2018.11.003 0 2 0 98 LRP6 protein, human|*Low Density Lipoprotein Receptor-Related Protein-6|Wnt Proteins|Intercellular Signaling Peptides and Proteins|LDL-Receptor Related Proteins|Wnt Signaling Pathway|Protein Binding|Binding Sites|Ligands|Cell Line 22 DKKL1 29643039 Nan Fang Yi Ke Da Xue Xue Bao 2018 PMC6744168 0 0 0 98 Humans|Male|*Asthenozoospermia|*Spermatozoa|Sperm Motility|RNA, Messenger|DKKL1 protein, human|Intercellular Signaling Peptides and Proteins 22 DLEC1 30516882 Adv Clin Exp Med 2018 10.17219/acem/84935 4 7 0 54 *DNA Methylation|Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Lung|*Cell-Free Nucleic Acids|Promoter Regions, Genetic|Tumor Suppressor Proteins|Biomarkers, Tumor|Genes, Tumor Suppressor 69 DLEC1 30324802 Epigenomics 2018 10.2217/epi-2018-0035 0 2 0 54 Humans|Female|*Carcinoma, Ovarian Epithelial|*Prognosis|*Ovarian Neoplasms|CDH1 protein, human|*Cadherins|*Antigens, CD|Neoplasms, Glandular and Epithelial|DNA Methylation|Promoter Regions, Genetic|Tumor Suppressor Proteins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|SFRP5 protein, human|Eye Proteins|Membrane Proteins|DLEC1 protein, human 69 DLEC1 30126609 Bull Cancer 2018 10.1016/j.bulcan.2018.05.004 4 1 0 54 *Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Air Pollution, Indoor|China|DNA Modification Methylases|Promoter Regions, Genetic|DNA Methylation|Tumor Suppressor Proteins|Death-Associated Protein Kinases|Cyclin-Dependent Kinase Inhibitor p16|Apoptosis Regulatory Proteins|Cadherins 69 DLEC1 30020823 Pediatr Hematol Oncol 2018 10.1080/08880018.2018.1467986 0 0 0 54 Humans|Child|Adolescent|*Epigenesis, Genetic|DNA Methylation|Genes, Tumor Suppressor|CDKN2A Gene|Promoter Regions, Genetic|Tumor Suppressor Proteins|*Lymphomas|Gene Expression Regulation, Neoplastic|Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Biomarkers, Tumor|Oligonucleotide Array Sequence Analysis|DLEC1 protein, human|PRDX2 protein, human|Peroxiredoxins|DAPK1 protein, human|Death-Associated Protein Kinases 69 DLEC1 29290793 Theranostics 2018 PMC5743460 10.7150/thno.20893 9 40 0 54 69 DLEU7 30208014 J Assoc Genet Technol 2018 0 2 0 16 Humans|Adult|*Leukemia, Lymphocytic, Chronic, B-Cell|*MicroRNAs|Downregulation|Apoptosis|Chromosomal Abnormalities|NF kB|MIRN16 microRNA, human 23 DLEU7 29755503 Front Genet 2018 PMC5932955 10.3389/fgene.2018.00128 0 1 0 16 Animals|Female|*Genome-Wide Association Study|*Chickens|*Eggs|Phenotype|Quantitative Trait Loci|Genotype|Breeding|Polymorphism, Single Nucleotide|Breeding, Selective|Genomics 23 DLEU7 29364477 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201801_14107 2 3 0 16 *RNA, Long Noncoding|*Wnt Pathway|*Colorectal Cancer|Cell Proliferation|Cell Movement|beta Catenin|Gene Expression Regulation, Neoplastic|*Catenins|Epithelial-Mesenchymal Transition|Cell Line, Tumor|*Colonic Neoplasms|Apoptosis|Lymphatic Metastasis|Xenograft Model Antitumor Assays 23 DMRTA2 30143575 J. Neurosci. 2018 PMC6191521 10.1523/JNEUROSCI.0375-18.2018 4 0 0 12 *Transcription Factors|Homeodomain Proteins|Telencephalon|Neural Stem Cells|Cerebral Cortex|Neurons|Gene Expression Regulation, Developmental 25 DMRTA2 29883638 Exp. Eye Res. 2018 PMC6167154 10.1016/j.exer.2018.06.004 8 0 0 12 Mice|Animals|*Transcriptome|Phosphatidylinositol 3-Kinases|Lens, Crystalline|Crystallins|Cell Differentiation|Epithelial Cells|mRNA|Gene Expression Regulation, Developmental|Cell Proliferation|STAT5A protein, human|Tumor Suppressor Proteins|Signal Transduction|Cell Cycle|STAT5 Transcription Factor 25 DMRTA2 29290336 Am. J. Hum. Genet. 2018 PMC5777936 10.1016/j.ajhg.2017.12.003 22 0 0 12 Humans|*Genome-Wide Association Study|*Atrial Fibrillation|Genetic Predisposition to Disease|*Regulatory Sequences, Nucleic Acid|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Homeodomain Proteins|Heart|Norway 25 DMXL2 30237576 Genet. Med. 2018 PMC6752307 10.1038/s41436-018-0138-x 13 0 0 56 Exome|Genetic Testing|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|Phenotypes|Genomics|Homozygote|Mutation|Genetic Variation 27 DNAH9 30471718 Am. J. Hum. Genet. 2018 PMC6288205 10.1016/j.ajhg.2018.10.020 8 1 0 77 Humans|DNAH9 protein, human|*Axonemal Dyneins|Axoneme|Kartagener Syndrome|Cilia|*Mutations|Phenotype|Pedigree 40 DNAH9 30471717 Am. J. Hum. Genet. 2018 PMC6288320 10.1016/j.ajhg.2018.10.016 16 0 0 77 Humans|Male|*Cilia|DNAH9 protein, human|*Axonemal Dyneins|*Axoneme|Kartagener Syndrome|*Mutations|Pedigree|Phenotype|Sequencing, Next-Generation|Infertility, Male|Paramecium 40 DNAH9 30282721 Thorax 2018 10.1136/thoraxjnl-2018-211797 1 0 0 77 *Tobacco Smoke Pollution|*Asthma|Bronchial Hyperreactivity|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Smoking|*Bronchi|Adenosine Triphosphatases|Epidemiological Study 40 DNAH9 29851510 Am. J. Respir. Cell Mol. Biol. 2018 PMC6178159 10.1165/rcmb.2017-0436OC 5 0 0 77 Humans|DNAH9 protein, human|Axonemal Dyneins|Axoneme|Cilia|Kartagener Syndrome|Phenotype|Kinesin|Mutation|Cultured Cells|Lung 40 DNAH9 29635245 Int. Arch. Allergy Immunol. 2018 10.1159/000488014 3 0 0 77 *Down-Regulation|*Nasal Mucosa|Allergic Rhinitis|Th2 Cells|Immunoglobulin E|Cilia|RNA, Messenger 40 dnajc10 30021839 J. Biol. Chem. 2018 PMC6130956 10.1074/jbc.RA118.004183 5 5 0 331 Humans|*Endoplasmic Reticulum-Associated Degradation|*Mannosidases|Endoplasmic Reticulum|Protein Folding|Membrane Proteins|Mannose|*Redox|HEK293 Cells|EDEM1 protein, human 32 dnajc10 29890952 BMC Genomics 2018 PMC5996485 10.1186/s12864-018-4827-2 0 4 0 331 Male|Humans|Mice|Animals|*Transgenic Mouse|*Genes, Modifier|*Prostate|*Prostate Cancer|Quantitative Trait Loci|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Expression Regulation, Neoplastic|Disease Models, Animal|Phenotype|Carcinoma, Neuroendocrine|Genetics, Population|Ccdc115 protein, human|Nerve Tissue Proteins 32 DNAJC14 30563838 J. Biol. Chem. 2018 PMC6369273 10.1074/jbc.REV118.002804 24 5 0 65 Humans|*Friends|molecular chaperone GRP78|*Heat-Shock Proteins|*Endoplasmic Reticulum|HSP40 Heat-Shock Proteins|Molecular Chaperones|Heat Shock Protein 70|Membrane Proteins|Folding, Protein|Protein Binding 20 DNAJC14 30518653 J. Virol. 2018 PMC6384085 10.1128/JVI.01714-18 3 1 0 65 Cattle|Swine|Animals|*Pestiviruses|*CRISPR-Cas Systems|Diarrhea Viruses, Bovine Viral|Diarrhea Virus 1, Bovine Viral|RNA, Viral|Virus Replication|Bovine Virus Diarrhea-Mucosal Disease|Viral Nonstructural Proteins|*Molecular Chaperones|RNA Helicases|Genome, Viral|Cell Line|Amino Acid Sequence 20 DNAJC14 29580969 Semin. Cell Dev. Biol. 2018 10.1016/j.semcdb.2018.03.016 8 0 0 65 Golgi Apparatus|Secretion Pathways|Protein Transport|CFTR protein, human|Cystic Fibrosis Transmembrane Conductance Regulator|Endoplasmic Reticulum|Plasma Membrane|Proteins|Endoplasmic Reticulum Stress|Eukaryotic Cells 20 DNASE1L3 30593563 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6329986 10.1073/pnas.1815031116 9 0 0 81 Humans|Mice|Animals|Chromatin|Endodeoxyribonucleases|DNA|Cell-Free Nucleic Acids|Dnase1l3 protein, mouse 67 dnmt2 30170023 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 2018 10.1016/j.cbpb.2018.08.007 2 0 0 138 Male|Female|Animals|*Nile Tilapia|*DNA Methylation|Phylogeny|Epigenesis, Genetic|Ovary|Testis|*Gonads|*DNA Modification Methylases|Fish Proteins|Spermatocytes|Gene Expression Regulation, Developmental|Tilapia|Oocytes|Amino Acid Sequence|Head Kidney|DNA 178 dnmt2 30093495 EMBO J. 2018 PMC6138434 10.15252/embj.201899777 18 0 0 138 Humans|Mice|Animals|*Nucleoside Q|Anticodon|tRNA|Schizosaccharomyces|Codon|Methylation|Eukaryotes|*Gene Expression|DNA (Cytosine-5-)-Methyltransferases|queuine|Guanine|Cell Line 178 dnmt2 30038377 Sci Rep 2018 PMC6056497 10.1038/s41598-018-29377-8 2 1 0 138 Bees|Animals|DNA Methylation|*DNA Modification Methylases|DNA (Cytosine-5-)-Methyltransferases|Processes, Epigenetic|DNA (Cytosine-5-)-Methyltransferase 1|Gene Expression|DNA 178 dnmt2 29932056 J. Genet. 2018 2 0 0 138 Animals|Humans|*X Chromosome Inactivation|*Epigenetic Process|*X Chromosome, Human|DNA Methylation|DNA (Cytosine-5-)-Methyltransferases|*Epigenetics|lncRNA|miRNAs 178 dnmt2 29892076 Sci Rep 2018 PMC5995894 10.1038/s41598-018-27118-5 3 5 0 138 *Nucleoside Q|*S pombe|*tRNA|RNA, Transfer, Asp|Methylation|DNA (Cytosine-5-)-Methyltransferases|Cytosine|*Catalysis|*Nucleosides 178 dnmt2 29875356 Nat Commun 2018 PMC5989218 10.1038/s41467-018-04518-9 0 2 0 138 *5 Azacytidine|*Methyltransferases|*Cytosine|*RNA|*Leukemia|*DNA Methylation|DNA (Cytosine-5-)-Methyltransferases|RNA, Neoplasm|*Biochemical Phenomena|Chromatin 178 DNTT 29879837 ACS Appl Mater Interfaces 2018 10.1021/acsami.8b07095 1 0 0 417 Semiconductor|Transistors, Electronic|Electronics 56 DOC2A 29754754 Neuron 2018 PMC6090561 10.1016/j.neuron.2018.04.022 16 1 0 31 *Neurons|Synaptic Transmission|Synaptotagmin I|Synaptic Vesicles|Excitatory Postsynaptic Potentials|Synapses|Neurotransmitter Agents|Calcium-Binding Proteins|Nerve Tissue Proteins|Hippocampus|Calcium 42 DOC2A 29445122 Eur. 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Genet. 2018 PMC5945616 10.1038/s41431-018-0102-x 1 0 0 31 Child|Adult|Humans|*Speech|Retrospective Studies|Chromosome Disorders|Chromosome Deletion|Autism|Apraxias|Intellectual Disability|Phenotype|Speech Disorders|DNA Copy Number Variations|Heterozygote|Language|*Chromosome Structures|Cohort Studies 42 DOC2B 30369065 J Diabetes Investig 2018 PMC6497606 10.1111/jdi.12965 1 13 0 90 Animals|Mice|*Insulin|*SNARE|*Phosphorylation|*Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins|*Insulin, Regular, Human|*Biological Transport|Insulin Secretion|Glucose|Insulin Resistance|*Protein Binding|Calcium-Binding Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Adipocytes|Nerve Tissue Proteins|Homeostasis|Mice, Knockout|*Membrane Fusion 55 DOC2B 29754754 Neuron 2018 PMC6090561 10.1016/j.neuron.2018.04.022 16 1 0 90 *Neurons|Synaptic Transmission|Synaptotagmin I|Synaptic Vesicles|Excitatory Postsynaptic Potentials|Synapses|Neurotransmitter Agents|Calcium-Binding Proteins|Nerve Tissue Proteins|Hippocampus|Calcium 55 DOC2B 29661782 Diabetes 2018 PMC6014558 10.2337/db17-1352 2 2 0 90 Insulin|Insulin-Secreting Cells|Islets of Langerhans|Diabetes Mellitus, Type 1|Calcium-Binding Proteins|Insulin Resistance|Glucose|Exocytosis|Nerve Tissue Proteins|*Protective Agents|Muscle, Skeletal 55 DOC2B 29506054 J. Clin. Endocrinol. Metab. 2018 PMC6276681 10.1210/jc.2017-02492 3 0 0 90 *Diabetes Mellitus, Type 1|Islets of Langerhans|*Exocytosis|Insulin-Secreting Cells|Insulin|TYRP1 protein, human|*Membrane Glycoproteins|Calcium-Binding Proteins|*Biomarkers|Glucose|Nerve Tissue Proteins 55 DPP10 30410030 Transl Psychiatry 2018 PMC6224395 10.1038/s41398-018-0281-9 4 1 0 67 Humans|*Neurites|*Neurogenesis|Neurons|Neurite Outgrowth|Nerve Tissue Proteins|*Mutations|Cell Differentiation|Induced Pluripotent Stem Cells|Cells, Cultured|Pedigree|DISC1 protein, human|ZNF506 protein, human|Repressor Proteins|Kruppel-Like Transcription Factors 105 DPP10 30199657 Am. J. Respir. Crit. Care Med. 2018 PMC6396866 10.1164/rccm.201802-0304OC 0 3 0 67 Humans|Adult|*Omega-3 Fatty Acids|Eicosapentaenoic Acid|Docosahexaenoic Acids|alpha-Linolenic Acid|Fatty Acids, Unsaturated 105 DPP10 30134803 Mol. Med. 2018 PMC6016867 10.1186/s10020-018-0018-5 0 0 0 67 Genome-Wide Association Study|Genetic Loci|Polymorphism, Single Nucleotide|Genotype|*Parathyroid Hormone 105 DPP10 29997484 Front Behav Neurosci 2018 PMC6028559 10.3389/fnbeh.2018.00125 0 12 0 67 Child|Infant, Newborn|Female|Humans|Pregnancy|*DNA Methylation|*Prenatal Exposure Delayed Effects|ethyl glucuronide|Glucuronates|Meconium|Epigenesis, Genetic|Attention|Ethanol|Alcohol Drinking|P3 Event-Related Potential|Cognition|Cohort Studies|Biomarkers|*DNA 105 DPP10 29753051 Toxicol In Vitro 2018 PMC6464127 10.1016/j.tiv.2018.05.004 3 3 0 67 *Particulate Matter|*Up-Regulation|*Epithelial Cells|Air Pollutants|Bronchi|Cell Line|Reactive Oxygen Species|*Transcriptional Activation|*Respiration Disorders 105 DPP10 29385630 Toxicol. Sci. 2018 PMC5917778 10.1093/toxsci/kfy013 7 0 0 67 Humans|Female|Pregnancy|phthalic acid|*RNA, Long Noncoding|mono-isobutyl phthalate|*Phthalic Acids|Endocrine Disrupting Chemicals|Maternal Exposure|Placenta 105 DPP10 29361513 Dis Model Mech 2018 PMC5818078 10.1242/dmm.031369 0 10 0 67 Mice|Humans|Animals|Pyroglyphidae|Airway Remodeling|Asthma|Lung|Bronchoalveolar Lavage Fluid|Inflammation Mediators|Epithelial Cells|*Peptidyl-Dipeptidase A|Disease Models, Animal 105 DPP3 30548582 J. Cell. Physiol. 2018 10.1002/jcp.27800 1 1 0 97 Humans|Female|Mice|Animals|*Myocardial Reperfusion Injury|*Ventricular Remodeling|*Mothers|*Signal Transduction|*Downregulation|Smad3 Protein|MicroRNAs|Transforming Growth Factor beta1|*Transforming Growth Factor|RNA Interference|RNA, Small Interfering|Myocardium|SMAD3 protein, human 39 DPP3 29913224 Pharmacol. 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Med. 2018 PMC6082709 10.1038/s41591-018-0082-y 15 6 0 173 Humans|Mice|Animals|*Pyroptosis|Caspase 1|Dipeptidases|Inflammasomes|Macrophages|Apoptosis Regulatory Proteins|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|RAW 264.7 Cells|Monocytes|*Leukemia, Myeloid, Acute|HEK293 Cells|Dipeptides|Boronic Acids|DPP9 protein, human|DPP8 protein, human 129 DPP9 29888956 Epigenomics 2018 PMC6367732 10.2217/epi-2017-0146 4 0 0 173 Male|Female|*Body Mass Index|CpG Islands|*Epigenetic|DNA Methylation|Epigenesis, Genetic|Genome-Wide Association Study|Adipose Tissue|Diabetes Mellitus, Type 2 129 DPP9 29709545 Immunol. 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Biochem. Biotechnol. 2018 10.1080/10826068.2018.1466149 0 1 0 48 *Leuconostoc mesenteroides|alternansucrase|*Glycosyltransferases|Leuconostoc|*Brassica|Hydrogen-Ion Concentration|Sucrose|Temperature 49 DRP2 29623298 Wellcome Open Res 2018 PMC5861512 10.12688/wellcomeopenres.13673.1 2 14 0 48 Mice|Animals|*Charcot-Marie-Tooth Disease|periaxin|*Disease Models, Animal|*Membrane Proteins|CMT4f|Myelin Sheath|Schwann Cells|Mutations|Demyelinating Diseases 49 EBF3 30358834 Hum. Reprod. 2018 10.1093/humrep/dey319 8 0 0 150 Humans|Male|*Infertility, Male|CpG Islands|Sperm|Spermatogenesis|DNA Methylation|Fertility 75 EBF3 30352868 J. Med. Genet. 2018 10.1136/jmedgenet-2018-105527 2 0 0 150 Humans|*Translocation, Genetic|*Chromosome Disorders|*Sequencing, Whole Genome|Chromosome Breakpoints|*Abnormalities, Multiple|Chromosome Mapping|Phenotype 75 EBF3 30169696 Int. Immunol. 2018 10.1093/intimm/dxy058 1 0 0 150 Endothelial Cells|*Hematopoietic Stem Cells|Bone Marrow|Stem Cell Niche|Osteoblasts|CXCL12 protein, human|Chemokine CXCL12|Mesenchymal Stem Cells|Cell Differentiation|Stem Cell Factor|Transcription Factors|leptin receptor, human|Leptin Receptor|Cell Count 75 EBF3 30083784 J. Mol. Neurosci. 2018 10.1007/s12031-018-1129-8 3 0 0 150 Humans|Rats|Animals|*miRNAs|*Parkinson Disease|Substantia Nigra|Protein Interaction Maps|Gene Regulatory Networks|SLC6A3 protein, human|Dopamine Plasma Membrane Transport Proteins|Tyrosine Hydroxylase|Gene Expression Profiling|6 Hydroxydopamine|Gene Expression|Downregulation|Upregulation|EBF3 protein, human|Transcription Factors|MIRN218 microRNA, human 75 EBF3 29943428 Aging Cell 2018 PMC6052391 10.1111/acel.12797 6 11 0 150 Humans|Animals|Mice|*Alzheimer Disease|Amyloid beta-Peptides|BACE1 protein, human|Amyloid Precursor Protein Secretases|*Cell Cycle Proteins|Amyloid beta-Protein Precursor|*Disease Models, Animal|Aspartic Acid Endopeptidases|Presenilin-1|tau Proteins|Mice, Transgenic|Brain|SGO1 protein, human|Chromosome Instability|Haploinsufficiency|Phosphorylation 75 EBF3 29913442 Cell. Physiol. Biochem. 2018 10.1159/000490208 1 1 0 150 Humans|*Bird Fancier's Lung|*Th2 Cells|Th1 Cells|IL10 protein, human|IL10|*Pulmonary Fibrosis|Interleukin-4|Interferon-gamma|*Blood Cells|DNA Methylation|Disease Progression|Flow Cytometry|*Blood Cell Count|EBF3 protein, human|Transcription Factors 75 EBF3 29869132 Brain Struct Funct 2018 10.1007/s00429-018-1687-0 1 0 0 150 *Neurogenesis|*Cerebral Cortex|Transcription Factor|GDF10 protein, human|*GDF-10|Telencephalon|Homeodomain Proteins|Amygdala|Gene Expression Regulation, Developmental|Neurons|Olfactory Bulbs, Accessory|*Corticomedial Nuclear Complex 75 EBF3 29751772 Stem Cell Res Ther 2018 PMC5948821 10.1186/s13287-018-0848-7 1 0 0 150 Humans|*Human Induced Pluripotent Stem Cells|*Cell Differentiation|*Retina|Lineages, Cell|Pluripotent Stem Cells|Retinal Pigment Epithelium|Cells, Cultured 75 EBF3 29750239 Acta Biochim. Biophys. Sin. 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Cancer Inst. 2018 PMC5939858 10.1093/jnci/djx083 6 1 0 150 Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Whole Exome Sequencing|*Study, Genetic Association|Germ-Line Mutation|Pedigree|Genetic Predisposition to Disease|Exome|Eye Neoplasms 75 EBF3 29298096 DNA Cell Biol. 2018 10.1089/dna.2017.4012 9 6 0 150 Animals|Mice|*RNA, Long Noncoding|*Alzheimer Disease|Amyloid beta-Peptides|*Apoptosis|Peptide Fragments|Hippocampus|Neurons|Cell Line, Tumor|Upregulation|siRNA|Brain|Disease Models, Animal|Ebf3 protein, mouse|Transcription Factors 75 edil3 30455459 Nat. Immunol. 2018 PMC6291356 10.1038/s41590-018-0249-1 15 8 0 230 Humans|Mice|Animals|*Phagocytosis|*Macrophage|*Inflammation|Neutrophils|Periodontitis|Cytokines|Mice, Transgenic|Carrier Proteins|Disease Models, Animal|Cell Adhesion|Apoptosis|Upregulation 115 edil3 30278915 J. Surg. Res. 2018 10.1016/j.jss.2018.04.066 1 11 0 230 Mice|Animals|*Chondrocytes|Osteoarthritis|Cartilage, Articular|*Protein Binding|Signal Transduction|*Protective Agents|Carrier Proteins|Anoikis|Cells, Cultured|*Protein Transport|Integrins 115 edil3 30243807 Pathol. Res. Pract. 2018 10.1016/j.prp.2018.09.010 3 1 0 230 *Squamous Cell Carcinoma of Head and Neck|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|MicroRNAs|Head and Neck Neoplasms|Biomarkers, Tumor|Computational Biology 115 edil3 29684347 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.04.158 1 0 0 230 Humans|Animals|*Peritoneal Diseases|Tissue Adhesions|Peritoneum|Tissue Plasminogen Activator|Fibrosis|Inflammation|Plasminogen Activator Inhibitor 1|Postoperative Complications|Transforming Growth Factor beta1|Inflammation Mediators|Disease Models, Animal 115 edil3 29437247 Immunol. Cell Biol. 2018 10.1111/imcb.12023 2 3 0 230 Humans|IL17A protein, human|*Interleukin-17|*Asthma|Eosinophils|Bronchoalveolar Lavage Fluid|Hypersensitivity|Cytokines|Ovalbumin|ICAM1 protein, human|Intercellular Adhesion Molecule-1|Inflammation|Interferon-gamma 115 edil3 29393238 Oncology 2018 10.1159/000485658 1 1 0 230 Humans|*Triple-Negative Breast Cancer|Receptors, Progesterone|Prognosis|Receptors, Estrogen|Receptor, ErbB-2|Carcinoma, Ductal, Breast|Biomarkers, Tumor 115 edil3 29375985 Int J Ophthalmol 2018 PMC5767652 10.18240/ijo.2018.01.04 2 7 0 230 Humans|*Epithelial-Mesenchymal Transition|*Epithelial Cells|Capsule Opacification|Transforming Growth Factor beta2|Lens, Crystalline|Cell Movement|Cells, Cultured|Signal Transduction|Cell Line|Cell Proliferation|Blotting, Western|EDIL3 protein, human|Carrier Proteins 115 EFHD2 30559642 Front Neurosci 2018 PMC6286997 10.3389/fnins.2018.00879 1 1 0 299 *tau Proteins|Amyloidogenic Proteins|Alzheimer Disease|Amyloid|Phosphorylation|Calcium-Binding Proteins|Brain|thioflavin T|*Benzothiazoles 54 EFHD2 30426778 Epigenomics 2018 10.2217/epi-2018-0132 4 0 0 299 *RNA, Long Noncoding|*miRNA|*mRNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Computational Biology|*Asthma 54 EFHD2 30405162 Sci Rep 2018 PMC6220333 10.1038/s41598-018-34802-z 0 0 0 299 Humans|Sp1 protein, human|*Sp1 Transcription Factor|*Promoter Regions, Genetic|EFHD2 protein, human|*Calcium-Binding Proteins|Base Sequence|Binding Sites|Gene Expression Regulation|Transcription, Genetic|Transcriptional Activation|Genes, Reporter|5' Flanking Region|5' Untranslated Region|Sequences, Conserved|Protein Binding 54 EFHD2 30318148 Cell 2018 10.1016/j.cell.2018.09.011 3 2 0 299 Mice|Animals|*Phosphorylation|Interferon Receptor|*Macrophage|Listeriosis|Signal Transduction|Interferon-gamma|Cell Membrane|Cell Movement|Protein Transport|EFHD2 protein, mouse|Calcium-Binding Proteins 54 EFHD2 30275048 J. Immunol. 2018 PMC6200634 10.4049/jimmunol.1800839 0 3 0 299 Humans|Mice|Animals|*EF Hand Motifs|*T-Lymphocytes, Cytotoxic|Synapse, Immunological|GZMB protein, human|Granzyme B|Lymphocyte Activation|Calcium-Binding Proteins|Signal Transduction|EFHD2 protein, human|EFHD2 protein, mouse 54 EFHD2 29421811 Cell. Physiol. Biochem. 2018 10.1159/000487285 6 11 0 299 Animals|*Diabetic Nephropathies|*Podocytes|*MAPK, p38|*Apoptosis|*Mitochondria|Kidney Glomerulus|*Epithelial Cells|Streptozocin|Diabetes Mellitus, Experimental|Ca2+-binding protein-1|Calcium-Binding Proteins|Signal Transduction|Glucose|Cells, Cultured 54 EFHD2 29415882 JCI Insight 2018 PMC5821171 10.1172/jci.insight.95396 3 2 0 299 Mice|Animals|*Macrophage|IL10 protein, human|IL10|Sepsis|Lipopolysaccharides|Toll-Like Receptor 4|Cytokines|Cecum|STAT3 protein, human|STAT3 Transcription Factor|Lung|Signal Transduction|Disease Models, Animal|Ligation|EFHD2 protein, mouse|Calcium-Binding Proteins 54 EFHD2 29348465 Sci Rep 2018 PMC5773677 10.1038/s41598-018-19645-y 0 0 0 299 Neoplasm Recurrence, Local|*Adenocarcinoma of Lung|*Epithelial-Mesenchymal Transition|Lung Neoplasms 54 EFHD2 29337116 Stem Cell Reports 2018 PMC5830914 10.1016/j.stemcr.2017.12.010 2 4 0 299 *Neurogenesis|*Hippocampus|Calcium-Binding Proteins 54 EGR4 30556283 J. Cell. Mol. Med. 2018 PMC6349159 10.1111/jcmm.14056 4 10 0 95 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|RNA, Long Noncoding|Up-Regulation|A549 Cells|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|MicroRNAs|Carcinogenesis|Cell Movement|Apoptosis|Transcriptional Activation|Cell Transformation, Neoplastic|mRNA Stability 82 EGR4 30229969 Anim. Genet. 2018 10.1111/age.12722 3 0 0 95 Animals|*Goat|Pakistan|Genetics, Population|Breeding|Inbreeding|Gene Frequency|Linkage Disequilibrium|Selection, Genetic|Genetic Variation|Genotype|Phenotype|Heterozygote|Population Density|Polymorphism, Single Nucleotide|Genetic Structures 82 EGR4 29945546 BMC Genomics 2018 PMC6020320 10.1186/s12864-018-4871-y 7 12 0 95 Animals|*Transcription Factors|Diabetes Mellitus, Type 2|*Phenotype|*Regulatory Regions|Quantitative Trait Loci|Gene Expression Regulation|Meat|Adipose Tissue|Gene Expression Profiling|Gene Expression|RNA, Messenger|Lipid Metabolism|Muscle, Skeletal 82 EGR4 29683733 FASEB J. 2018 10.1096/fj.201701096RR 8 3 0 95 Humans|Male|Mice|Animals|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|Spermatogenesis|Spermatogonia|Testes|*Male Sterility|*Cell Cycle Proteins|*Signal Transduction|Spermatids|Cell Differentiation|Stem Cells|Cytokinesis|*Cell Nucleus|FOXO1 protein, human|Forkhead Box Protein O1|Cep55 protein, human|Nuclear Proteins|Foxo1 protein, mouse 82 EGR4 29580816 Biochimie 2018 10.1016/j.biochi.2018.03.010 0 0 0 95 Animals|Rats|*MAP Kinase Signaling System|*Stroke|*Brain Ischemia|Infarction, Middle Cerebral Artery|Reperfusion Injury|Neuroprotective Agents|JNK Mitogen-Activated Protein Kinases|*Downregulation|Disease Models, Animal|Egr2 protein, rat|Early Growth Response Protein 2 82 EGR4 29399809 Transfusion 2018 10.1111/trf.14515 2 1 0 95 P Blood-Group System|Globosides|Alleles|Genotype|Galactosyltransferases|Phenotype|Polymorphism, Single Nucleotide 82 EHBP1 30333761 Front Physiol 2018 PMC6176378 10.3389/fphys.2018.01393 2 17 0 98 Humans|Animals|*Pulmonary Arterial Hypertension|intersectin 1|Adaptor Proteins, Vesicular Transport|Lung|*Familial Primary Pulmonary Hypertension|Endothelial Cells|GZMB protein, human|Granzyme B 29 EHBP1 30209220 Proc. 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Immunopharmacol. 2018 10.1016/j.intimp.2018.12.009 1 3 0 678 Animals|*Mesenchymal Stem Cells|*Exosomes|*Antigen|Immunomodulation|Cell Differentiation|T-Lymphocytes, Regulatory|Encephalomyelitis, Autoimmune, Experimental|Interleukin-10|Cell Proliferation|Cells, Cultured 195 ELF4 30393540 Hortic Res 2018 PMC6210193 10.1038/s41438-018-0063-9 0 0 0 678 Arabidopsis Proteins|Arabidopsis|Gene Expression Regulation, Plant|Photoperiod|Flowers|Chrysanthemum|Light|Circadian Rhythm|Phenotype 195 ELF4 30341009 Mol. Ther. 2018 PMC6318784 10.1016/j.ymthe.2018.09.016 4 0 0 678 Humans|*Adenovirus|Oncolytic Viruses|Oncolytic Virotherapy|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Adenovirus E1A Proteins|RNA, Micro|Virus Replication|Xenograft Model Antitumor Assays|Cell Line, Tumor|ELF4 protein, human|DNA-Binding Proteins|Transcription Factors|KLF8 protein, human|Repressor Proteins|MIRN485 microRNA, human 195 ELF4 30157134 Pain 2018 PMC6800106 10.1097/j.pain.0000000000001387 3 2 0 678 Mice|Rats|Animals|*Nociceptors|*Pyruvaldehyde|Dorsal Root Ganglion|Pain, Neuropathic|Painful Diabetic Neuropathy|Hyperalgesia|Pain Threshold|Diabetes Mellitus, Experimental|Disease Models, Animal 195 ELF4 30089112 PLoS ONE 2018 PMC6082502 10.1371/journal.pone.0200385 6 22 0 678 Humans|RNA, Micro|Vesiculovirus|Interferon Type I|Immunity, Innate|Interferon Regulatory Factor-3|Interferon-beta|Gene Expression Regulation|Macrophages|Virus Replication|Protein-Serine-Threonine Kinases|Signal Transduction|HEK293 Cells|Phosphorylation|ELF4 protein, human|DNA-Binding Proteins|Transcription Factors|MIRN221 microRNA, human 195 ELK4 30068599 J. Immunol. 2018 PMC6121213 10.4049/jimmunol.1800704 1 30 0 234 Mice|Animals|*Signal Transduction|ets-Domain Protein Elk-4|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Cell Differentiation|Pathway, ERK|Mice, Transgenic|Mice, Knockout|Gene Expression Regulation|Lymphocyte Activation|Early Growth Response Protein 1|Cells, Cultured 110 ELK4 29442044 Pharmazie 2018 10.1691/ph.2017.7686 0 0 0 234 Humans|oxidized low density lipoprotein|Lipoproteins, LDL|*Atherosclerosis|RHOA protein, human|*rhoA GTP-Binding Protein|Apoptosis|Macrophages|RNA, Long Noncoding|Elk3 protein, human|*Proto-Oncogene Proteins|*Transcription Factors|MicroRNAs|Downregulation|Lipoprotein-Associated Phospholipase A(2)|Gene Knockdown Techniques|Signal Transduction|Viability, Cell|Cytokines 110 EMP2 30257973 Diabetes 2018 10.2337/db17-1434 8 0 0 271 Humans|Animals|Rats|*miRNA|*Muscle, Smooth, Vascular|*Rats, Wistar|*Rats, Zucker|*Myocytes, Smooth Muscle|Cell Proliferation|*Phenotype|Downregulation|Cells, Cultured|Diabetes Mellitus, Type I|Vascular Remodeling|Signal Transduction|Diabetes Mellitus, Type II|Upregulation 97 EMP2 30218306 Clin Transl Oncol 2018 10.1007/s12094-018-1941-1 5 0 0 271 Humans|*Neoplastic Cells, Circulating|EPCAM protein, human|EpCAM|MCF-7 Cells|Antigens, Neoplasm|Biomarkers, Tumor|Cell Separation|Cell Adhesion Molecules|Cell Line, Tumor|Epithelial-Mesenchymal Transition|Flow Cytometry|Cell Count|EMP2 protein, human|Membrane Glycoproteins 97 EMP2 29940748 Neoplasma 2018 10.4149/neo_2018_170510N337 3 1 0 271 *Glioma|*Genes, Tumor Suppressor|MicroRNAs|Apoptosis|Downregulation|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Viability, Cell|Signal Transduction 97 EMP2 29881845 Phys Chem Chem Phys 2018 10.1039/c8cp02489h 0 0 0 271 Electrons|Quantum Theory|Thermodynamics|Models, Chemical|Models, Molecular|*Electronic|Algorithms 97 ENOSF1 30134598 Int J Mol Sci 2018 PMC6163881 10.3390/ijms19092473 2 1 0 12 Humans|Female|*Thymidylate Synthase|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|Genetic Association Studies|Polymorphism, Single Nucleotide|Adenocarcinoma, Mucinous|Genotype|Case-Control Studies|TYMS protein, human 23 EPB41L4A 30568280 Sci Rep 2018 PMC6299474 10.1038/s41598-018-36231-4 5 0 0 29 Humans|*RNA, Long Noncoding|*Docetaxel|*mRNA|Gene Expression Regulation, Neoplastic|taxane|Taxanes|Drug Resistance, Neoplasm|Gene Regulatory Networks|Gene Expression Profiling|Sequencing, RNA|Paclitaxel|Cell Line, Tumor|MicroRNAs|Gene Ontology|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B|High-Throughput Nucleotide Sequencing|Bridged-Ring Compounds 30 EPB41L4A 30249102 Neoplasma 2018 10.4149/neo_2018_170713N480 6 5 0 29 *Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Apoptosis|Downregulation|MicroRNAs|Cell Line, Tumor|Up-Regulation|Signal Transduction|Viability, Cell 30 EPB41L4A 29925043 Transl Oncol 2018 PMC6008483 10.1016/j.tranon.2018.05.010 3 2 0 29 Male|Female|*Carcinoma, Renal Cell|*Tuberous Sclerosis|Phosphatidylinositol 3-Kinases|Tuberous Sclerosis Complex 2 Protein|Kidney Neoplasms|Tuberous Sclerosis Complex 1 Protein|Mutations|MTOR protein, human|TOR Serine-Threonine Kinases|Tumor Suppressor Proteins|Sequencing, Whole Exome|Loss of Heterozygosity|PBRM1 protein, human|Nuclear Proteins|Genes, Regulator|Signal Transduction|Mutations, Germline|SMARCA4 protein, human 30 EPB41L4A 29703930 Sci Rep 2018 PMC5923232 10.1038/s41598-018-24967-y 5 2 0 29 Humans|*Whole Exome Sequencing|*Colon|Exomes|Mutations|Anorectal Anomalies|Open Reading Frames|Genes, Regulator|TSPAN32 protein, human|Tetraspanins 30 EPB41L4B 30440051 PLoS ONE 2018 PMC6237394 10.1371/journal.pone.0207470 0 1 0 90 Animals|AREG protein, human|*Amphiregulin|*Cells, Epithelial|Cell Polarity|Epidermal Growth Factor|Cell Proliferation|Signal Transduction|Cell Movement|Tight Junctions|Membrane Glycoproteins|Cell Line, Tumor|Protein Binding 23 EPB41L4B 30001177 Epigenetics 2018 PMC6291301 10.1080/15592294.2018.1497387 2 0 0 90 Humans|Child|Female|Pregnancy|*DNA Methylation|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|*Epigenome|*Placenta|CpG Islands|Maternal Exposure|Epigenesis, Genetic|*Cohort Studies|Prenatal Exposure Delayed Effects|Fetal Blood|Genome-Wide Association Study|DNA|SMAP1 protein, human|Membrane Proteins|GTPase-Activating Proteins 23 EPC2 30578870 J. Allergy Clin. Immunol. 2018 PMC6556402 10.1016/j.jaci.2018.10.070 1 3 0 66 Male|Female|*Interleukin-13|*Oestradiol|Eosinophilic Esophagitis|*Esophageal Mucosa|Esophagus|Epithelial Cells|*Estrogens|*Protective Agents 54 EPC2 29729938 J. Allergy Clin. Immunol. 2018 PMC6448407 10.1016/j.jaci.2018.03.017 3 1 0 66 Humans|*Eosinophilic Esophagitis|*Sodium-Hydrogen Exchanger 3|*Extracellular Space|Esophagus|Interleukin-13|Eosinophils|Epithelial Cells 54 EPC2 29721194 Oncotarget 2018 PMC5922388 10.18632/oncotarget.24969 3 0 0 66 Female|Humans|Sarcoma, Endometrial Stromal|Endometrial Stromal Tumors|DNA-Binding Proteins|Transcription Factors|Gene Fusion|Oncogene Proteins, Fusion|Polycomb-Group Proteins|Translocation, Genetic|Chromosomal Proteins, Non-Histone|Endometrial Neoplasms|Sarcoma|In Situ Hybridization, Fluorescence|Soft Tissue Neoplasms 54 EPG5 30335568 Autophagy 2018 PMC6351132 10.1080/15548627.2018.1535290 1 2 0 85 Humans|Female|Mice|Animals|Uropathogenic Escherichia coli|Urinary Tract Infections|Escherichia coli Infections|Urothelium|*Autophagy|Urinary Bladder|*Genes, Regulator|IL1B protein, human|Interleukin-1 beta|Protein Transport|Epithelial Cells|Cell Division|Rab27B protein, human|rab GTP-Binding Proteins|RAB33B protein, human|ATG16L1 protein, human|Autophagy-Related Proteins|Rab27b protein, mouse 47 EPG5 30152144 Am. 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A 2018 10.1002/ajmg.a.40500 0 0 0 85 Humans|Female|Child, Preschool|Absent corpus callosum cataract immunodeficiency|*Mutation, Missense|Comparative Genomic Hybridization|Japan|*Agenesis of Corpus Callosum|*Cataracts|*Exon|*Heterozygote|*Mutations|Vesicular Transport Proteins|Lysosome-Associated Membrane Glycoproteins|Phenotype|Sequencing, Whole Exome|Corpus Callosum|Immunologic Deficiency Syndromes|EPG5 protein, human 47 EPG5 30009132 Mol Genet Metab Rep 2018 PMC6043467 10.1016/j.ymgmr.2018.03.004 3 1 0 85 Humans|*Whole Exome Sequencing|Estonia|*Disorder, Mitochondrial|Exome|Sequence Analysis, DNA|mtDNA|Mutation|Mitochondria 47 EPG5 29996716 Autophagy 2018 PMC6152536 10.1080/15548627.2018.1493044 7 6 0 85 Mice|Animals|*Trehalose|Diabetes Mellitus, Type 2|*Thermogenesis|TFEB protein, human|*Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|*Hepatocyte|fibroblast growth factor 21|Fibroblast Growth Factors|Uncoupling Protein 1|Autophagy|Liver|Signal Transduction|Energy Metabolism|Fasting|Fatty Liver|Protein, Mitochondrial|Adipose Tissue, White|Glucose 47 EPG5 29983806 Open Access Maced J Med Sci 2018 PMC6026433 10.3889/oamjms.2018.271 0 0 0 85 Humans|Infant|Absent corpus callosum cataract immunodeficiency|Saudi Arabia|*Agenesis of Corpus Callosum|*Cataracts|Mutations|Phenotype|Lysosome-Associated Membrane Glycoproteins|Vesicular Transport Proteins|Corpus Callosum|Immunologic Deficiency Syndromes 47 EPG5 29681093 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.38676 1 0 0 85 Humans|Male|Child|Absent corpus callosum cataract immunodeficiency|*Agenesis of Corpus Callosum|*Cataracts|*Phenotype|Exon|Mutation|Lysosome-Associated Membrane Glycoproteins|Vesicular Transport Proteins|Heterozygote|Corpus Callosum|EPG5 protein, human 47 EPG5 29486404 J Psychiatr Res 2018 PMC6882010 10.1016/j.jpsychires.2018.01.016 1 0 0 85 Humans|United States|Genome-Wide Association Study|Depressive Disorder, Major|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Depression|Phenotype|United Kingdom 47 EPG5 29388501 Autophagy 2018 PMC5959325 10.1080/15548627.2018.1434372 0 1 0 85 Humans|*Autophagy|*Cell Death|Neurodegenerative Diseases|Neurons|Proteostasis 47 EPSTI1 30572883 Mol. Cancer 2018 PMC6302470 10.1186/s12943-018-0925-7 5 1 0 50 Humans|*Transcriptome|*Colorectal Cancer|BMP5 protein, human|*Bone Morphogenetic Protein 5|*Transcriptome Profiling|HCT116 Cells|*Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|HT29 Cells|*Genomics|Cell Movement|Down-Regulation|Cell Line, Tumor|*Colonic Neoplasms|Cell Proliferation|Signal Transduction 37 EPSTI1 30347820 Int J Mol Sci 2018 PMC6214106 10.3390/ijms19103259 2 9 0 50 Mice|Male|Humans|Female|Animals|*Mice, Inbred NOD|*Dacryoadenitis|Lacrimal Glands|Salivary Glands|Sjogren's Syndrome|T-Cells, Regulatory|Autoimmunity|Adoptive Transfer|*Signal Transduction|Gene Expression|Chemokines|Interferon Type I|Diabetes Mellitus 37 EPSTI1 30114595 Transl Oncol 2018 PMC6097464 10.1016/j.tranon.2018.07.014 7 11 0 50 Humans|*Colorectal Cancer|Peritoneal Neoplasms|CDH1 protein, human|E Cadherin|*Peritoneum|Biomarkers, Tumor|EPSTI1 protein, human|Neoplasm Proteins|Cell Line, Tumor|Signal Transduction|*Colonic Neoplasms|Mutation|Sequencing, Whole Exome|mRNA|Antigens, CD 37 EPSTI1 30083277 Theranostics 2018 PMC6071524 10.7150/thno.24106 43 12 0 50 Humans|*Triple-Negative Breast Cancer|*Prognosis|*Disease Progression|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Apoptosis|Upregulation 37 EPSTI1 29948145 J. Cancer Res. Clin. Oncol. 2018 10.1007/s00432-018-2684-7 2 0 0 50 Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|Proto-Oncogene Proteins B-raf|*Genomics|Mutation|*Data Aggregation 37 ERI3 29767205 Chem. Commun. 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Nephrol. 2018 PMC6394682 10.1007/s00467-018-4129-6 0 0 0 80 Humans|Child|*Edetic Acid|*Renal Dialysis|Arteriovenous Shunt, Surgical|Kidney Failure, Chronic|*Registry|Catheterization, Central Venous|Kidney Transplantation|Treatment Outcome|Time Factors 129 ESPN 30374605 Pediatr. Nephrol. 2018 10.1007/s00467-018-4122-0 1 0 0 80 Infant|Child|Humans|Nephrosis, congenital|*Nephrotic Syndrome|Renal Dialysis|Kidney Failure, Chronic|Peritoneal Dialysis|*Kidney Diseases|Kidney Transplantation|Risk Factors|Retrospective Studies|Registries|Time Factors|Age Factors 129 ESX1 30594716 J. Hazard. Mater. 2018 10.1016/j.jhazmat.2018.12.061 0 2 0 100 Mice|Female|Pregnancy|Animals|*Acrylamide|*Placental Development|Placenta|CASP3 protein, human|Caspase 3|Trophoblasts|Apoptosis|Embryo Resorption|Gene Expression|CASP8 protein, human|Caspase-8 73 ESX1 30257807 Int. J. Med. Microbiol. 2018 10.1016/j.ijmm.2018.06.010 0 0 0 100 *Mycobacterium smegmatis|*Cell Wall|Type VII Secretion Systems|Mycobacterium tuberculosis|Bacterial Proteins|Gene Clusters|Gene Deletion 73 ESX1 30054974 Andrology 2018 10.1111/andr.12528 2 0 0 100 Humans|Male|*Sperm Retrieval|*Testis|*Azoospermia|Spermatozoa|*Biomarkers 73 ESX1 30040967 Dev. Comp. Immunol. 2018 10.1016/j.dci.2018.07.022 3 2 0 100 Humans|Animals|Infection with Mycobacterium marinum|*Zebrafish|*Mycobacterium Infections, Nontuberculous|Mycobacterium marinum|Tuberculosis|Mycobacterium tuberculosis|Granuloma|Macrophages|Foam Cells|Disease Models, Animal|*Cell Differentiation 73 ESX1 29440900 Int J Nanomedicine 2018 PMC5804269 10.2147/IJN.S152400 6 14 0 100 Pregnancy|Humans|Female|Mice|Animals|titanium dioxide|*Placentation|*Titanium|*Apoptosis|Maternal Exposure|Metal Nanoparticles|Placenta|*Neovascularization, Pathologic|Cell Proliferation 73 ETV3 29915163 Aging (Albany NY) 2018 PMC6046229 10.18632/aging.101475 0 22 0 1655 Humans|*Upregulation|*Transcriptional Activation|ets Transcription Factors|Transcription Factor|Promoter Regions, Genetic|Trans-Activators|Proto-Oncogene Protein c-ets-2|DNA-Binding Proteins|Gene Expression Regulation|Proto-Oncogene Protein c-ets-1|Proto-Oncogene Proteins|Binding Sites|*Oncogenes|leukocyte-associated immunoglobulin-like receptor 1|*Receptors, Immunologic|Protein Binding|Luciferase|Cell Line 23 ETV3 29877893 Am J Dermatopathol 2018 10.1097/DAD.0000000000001191 0 0 0 1655 NCOA2 protein, human|*Nuclear Receptor Coactivator 2|*Translocation, Genetic|CD1a antigen|Antigens, CD1|Histiocytosis, Langerhans-Cell|*Lymphoma, Non-Hodgkin|Histiocytes|Skin|*Dendritic Cell Sarcoma, Interdigitating|Immunophenotyping|Dendritic Cells 23 ETV7 30478527 Transgenic Res. 2018 PMC6353817 10.1007/s11248-018-0104-z 0 1 0 205 Mice|Animals|Humans|*Transgenic Mouse|Proto-Oncogene Proteins c-ets|Transcription Factor|PTEN Phosphohydrolase|Oncogenesis|Gene Expression Regulation, Neoplastic|Cell Transformation, Neoplastic|Oncogene Proteins|Disease Models, Animal|Upregulation|ETV7 protein, human 43 ETV7 30341925 Clin Transplant 2018 10.1111/ctr.13429 1 0 0 205 *Kidney Transplantation|*Interferon Type I|Graft Rejection|Isoantibodies|Graft Survival|Allografts|Kidney Failure, Chronic|Gene Expression Profiling|Prognosis 43 ETV7 30258985 Sci Adv 2018 PMC6156121 10.1126/sciadv.aar3938 0 4 0 205 Humans|Mice|Animals|MTOR protein, human|*TOR Serine-Threonine Kinases|mTORC2|mTORC1|Rapamycin-Insensitive Companion of mTOR Protein|Regulatory-Associated Protein of mTOR|Rapamycin|Signal Transduction|Adaptor Proteins, Signal Transducing|Cell Proliferation|Tumor Cell Lines|RNA Interference|Antineoplastic Agents|RNA, Small Interfering|ETV7 protein, human|Proto-Oncogene Proteins c-ets 43 ETV7 30253797 Cancer Commun (Lond) 2018 PMC6156863 10.1186/s40880-018-0328-6 4 10 0 205 Humans|*Nasopharyngeal Carcinoma|*Downregulation|Nasopharyngeal Neoplasms|Neoplasm Invasiveness|Cell Movement|Snail Family Transcription Factors|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Neoplastic Processes|Signal Transduction|Transcription Factors|SERPINE1 protein, human|Plasminogen Activator Inhibitor 1 43 ETV7 30025229 Neoplasia 2018 PMC6077117 10.1016/j.neo.2018.06.008 2 3 0 205 Humans|Neoplasm Recurrence, Local|Doxorubicin|MCF7 Cells|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Downregulation|Apoptosis|ETV7 protein, human|Proto-Oncogene Proteins c-ets|DNAJC15 protein, human|HSP40 Heat-Shock Proteins 43 ETV7 29755409 Front Endocrinol (Lausanne) 2018 PMC5932191 10.3389/fendo.2018.00195 1 10 0 205 Horses|Animals|Female|Pregnancy|*Chorionic Gonadotropin, beta Subunit, Human|Trophoblast|Transcription Factors|Placenta|Nuclear Proteins|Homeodomain Proteins|Transcription, Genetic|Promoter Regions, Genetic|*Neuroglia|*B Cells|Cell Differentiation|Protein Binding 43 FADS3 30400035 Reproduction 2018 10.1530/REP-18-0145 0 2 0 58 Pregnancy|Humans|Female|Mice|Animals|Progesterone|Embryo Implantation|Decidua|Uteri|Estrogens|progesterone receptor B|Progesterone Receptor|Cells, Stromal|mRNA|Gene Expression Regulation, Developmental|Ovariectomy|RU486|Signal Transduction|Fatty Acid Desaturases|Fads3 protein, mouse 53 FADS3 30343921 J. 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Metab. 2018 PMC6915830 10.1210/jc.2018-00791 6 0 0 110 Humans|*Insulin Secretion|Diabetes Mellitus, Type 2|*Fructose-Bisphosphate Aldolase|Islet Cell|Hyperglycemia|Insulin|Blood Glucose|Glucose 91 FAIM2 29963304 Biomed Rep 2018 PMC6020445 10.3892/br.2018.1109 2 8 0 110 Humans|*Exome|*Coronary Artery Disease|Genome-Wide Association Study|Cross-Sectional Studies|Japan|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|Asian Continental Ancestry Group|Genotype|Alleles|*Cerebral Infarction|Case-Control Studies 91 FAIM2 29315561 J. 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Immunol. 2018 PMC6046480 10.1111/cei.13138 1 0 0 62 Humans|Mice|Animals|Leukocytes, Mononuclear|*Macrophages, Alveolar|*Proteins|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Asian Continental Ancestry Group|Lupus Erythematosus, Systemic|Genotypes|*Collagen Diseases|Sjogren's Syndrome|Autoimmunity|B Cells|*Disease, Rheumatic|Case-Control Studies|Quantitative Trait Locus|BLK protein, human|src-Family Kinases 25 farp1 30281149 J. 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Pharm. 2018 10.1021/acs.molpharmaceut.8b00566 4 0 0 83 Humans|*Chalkone|thienopyrimidine|*Chalcones|HEK293 Cells|*Pyrimidines|MCF 7 Cells|Drug Screening Assays, Antitumor|Cell Proliferation|*Phosphorylation|Apoptosis|Antineoplastic Agents|Structure-Activity Relationship|Hybrid-B|*Plasminogen Activators|Protein-Serine-Threonine Kinases|Serine 24 FASTK 29700004 Cancer Res. 2018 10.1158/0008-5472.CAN-17-3514 9 4 0 83 *Apoptosis|*Neoplastic Processes|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Alternative Splicing|Cell Movement|Signal Transduction|Gene Knockdown Techniques|Cell Survival|Xenograft Model Antitumor Assays|Carrier Proteins 24 FASTKD2 30546022 Transl Psychiatry 2018 PMC6293320 10.1038/s41398-018-0325-1 1 0 0 49 *Dopamine|*Schizophrenia|*Networks, Gene|DRD2 protein, human|Receptors, Dopamine D2|SNPs|Genome-Wide Association Study|Genetic Predisposition to Disease|Transcriptome Profiles|Quantitative Trait Loci|Whole Exome Sequencing|Cell Line 22 FASTKD2 30061372 Mol. Cell. Biol. 2018 PMC6168981 10.1128/MCB.00412-17 8 0 0 49 Humans|*Mitochondrial Proteins|ATP-Dependent Proteases|Mitochondria|DNA, Mitochondrial|mitochondrial processing peptidase|Metalloendopeptidases|Mitophagy|Proteostasis|HEK293 Cells|FASTKD2 protein, human|Protein-Serine-Threonine Kinases|LONP1 protein, human 22 FASTKD2 29681787 Clin Proteomics 2018 PMC5898006 10.1186/s12014-018-9192-2 5 2 0 49 Humans|*Neoadjuvant Therapy|*5 Fluorouracil|*Proteomics|*Chemoradiotherapy|Rectal Neoplasms|*Rectum|Antimetabolites, Antineoplastic|Adenocarcinoma|Gene Expression Regulation, Neoplastic 22 FBXO45 30150401 Proc. Natl. Acad. Sci. 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Eye Res. 2018 10.1016/j.exer.2018.03.017 1 0 0 183 Mice|Animals|*Retinal Bipolar Cells|*Retina|Photoreceptor, Cone|*Cell Differentiation|Retinal Rod Photoreceptor Cells|Transcription Factors|Terminal, Synaptic|Progenitor Cells|Interneurons|Mice, Inbred C57BL 109 FEZF2 29348628 Cell Death Dis 2018 PMC5833349 10.1038/s41419-017-0052-1 15 38 0 183 Humans|Mice|Animals|*Carcinoma, Pancreatic Ductal|Long Non-Coding RNA|Pancreatic Carcinoma|*Pancreatic Neoplasms|Cell Proliferation|Oncogenesis|*Disease Progression|Gene Expression Regulation, Neoplastic|RNA, Antisense|Cell Movement|Prognosis|Repressor Proteins|Cell Line, Tumor|Transcription Factors|Gene Knockdown Techniques|Apoptosis|MicroRNAs|MIRN107 microRNA, human 109 FEZF2 29291257 Ann. N. Y. Acad. Sci. 2018 10.1111/nyas.13529 4 0 0 183 Female|Humans|Mice|Male|Animals|Gender Bias|APECED protein|*Transcription Factors|*Autoimmune Diseases|Autoimmunity|Central Tolerance|Gene Expression Regulation|Immune Tolerance|Autoantigens|Epithelial Cells|Estrogens 109 FGL1 30580966 Cell 2018 PMC6365968 10.1016/j.cell.2018.11.010 48 1 0 118 Humans|Mice|Animals|Histocompatibility Antigens Class II|Lymphocyte Activation|*Ligands|Antigens, CD|Immunotherapy|CD4-Positive T-Lymphocytes|T-Lymphocytes, Cytotoxic|galiximab|Antibodies, Monoclonal|Cancer|Fibrinogen 50 FGL1 30460699 Lipids 2018 10.1002/lipd.12099 0 2 0 118 STAT3 protein, human|*STAT3 Transcription Factor|*Hep G2 Cells|*Fatty Acids, Unsaturated|Non alcoholic Fatty Liver Disease|Interleukin 6|Hepatocytes|Palmitic Acid|Oleic Acid|Signal Transduction|Neoplasm Proteins 50 FGL1 30406363 J. Mol. Med. 2018 PMC6326977 10.1007/s00109-018-1715-9 1 0 0 118 Animals|Mice|Mice, Inbred C57BL|*Radiation Pneumonitis|*Pulmonary Fibrosis|*Lung|*Radiation Injuries|Epithelial-Mesenchymal Transition|Upregulation|Disease Models, Animal 50 FGL1 30009716 Endocr Metab Immune Disord Drug Targets 2018 10.2174/1871530318666180716100543 1 2 0 118 Humans|Mice|Animals|*Non-alcoholic Fatty Liver Disease|*Liver|B-insulin|Insulin|Insulin Resistance|Diabetes Mellitus, Type 2|Hep G2 Cells|Lipids|Biotin 50 FGL1 29845203 Mol Med Rep 2018 PMC6072172 10.3892/mmr.2018.9097 1 12 0 118 Humans|*Stomach Neoplasms|Vimentin|Epithelial-Mesenchymal Transition|Cadherins|Snail Family Transcription Factors|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|Prognosis|Cell Proliferation|Adenocarcinoma|*Neoplastic Processes|Cell Line, Tumor|Lymphatic Metastasis|RNA, Small Interfering|Antigens, CD|Signal Transduction|Transcription Factors 50 FILIP1 29618024 J Mol Cell Biol 2018 PMC7191624 10.1093/jmcb/mjy025 15 2 0 40 Mice|Animals|*Muscle Development|*RNA, Long Noncoding|Myoblasts|MyoD Protein|Myotubes|Myogenin|Cell Differentiation|*DNA-Binding Proteins|Muscle, Skeletal|Cell Line 22 FILIP1 29331478 Gene 2018 10.1016/j.gene.2018.01.039 5 3 0 40 Mice|Animals|*RNA, Long Noncoding|*mRNA|Gene Ontology|*Myoblasts|Gene Regulatory Networks|Gene Expression Profiling|MicroRNAs|*Myotubes|Bioinformatics|Oligonucleotide Array Sequence Analysis|Cell Differentiation|Genomes|Upregulation 22 FILIP1L 30586196 J. Pineal Res. 2018 10.1111/jpi.12546 2 3 0 87 Female|Swine|Animals|*Oestradiol|*Melatonin|*Granulosa Cells|Oocytes|Progesterone|*Gene Expression|*Estrogens|Cells, Cultured 44 FILIP1L 30488423 J. Cell. Physiol. 2018 10.1002/jcp.27550 0 3 0 87 Mice|Animals|Endothelial Cells|ribosomal protein S6 kinase, 70kD, polypeptide 2|p70s6k|MTOR protein, human|Mammalian Target of Rapamycin|*Signal Transduction|DDIT3 protein, human|*Homologous Protein, C-EBP|Cell Proliferation|Apoptosis|Phosphoproteins|Downregulation|MicroRNAs|Cell Line, Tumor|Cell Cycle|Gene Expression Regulation, Neoplastic|Phosphorylation|Messenger RNA 44 FILIP1L 30026504 J. Hum. Genet. 2018 10.1038/s10038-018-0490-3 0 0 0 87 Humans|Middle Aged|*Untranslated Region|*Asian Continental Ancestry Group|*Wet Macular Degeneration|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|High-Temperature Requirement A Serine Peptidase 1|Complement Factor H|Gene Frequency|Genotype|Serine Endopeptidases|Case-Control Studies 44 FJX1 30193086 Hum Vaccin Immunother 2018 PMC6363157 10.1080/21645515.2018.1520584 0 0 0 72 Humans|Male|*Vaccines, Subunit|HLA-A2|Antigens, Neoplasm|Cancer Vaccines|T-Lymphocytes, Cytotoxic|*Head and Neck Cancer|*Peptides|Epitopes, T-Lymphocyte|*Vaccine Antigenicity|Neoplasm Proteins|Lymphocyte Activation|Squamous Cell Carcinoma of Head and Neck|Cell Line, Tumor|ELISPOT|Cytokines|Leukocytes, Mononuclear|FJX1 protein, human|Membrane Proteins 26 FKBP10 30326831 BMC Genomics 2018 PMC6192343 10.1186/s12864-018-5108-9 4 0 0 126 Animals|*Salmonids|Oncorhynchus|Salmon|Oligonucleotide Array Sequence Analysis|Gill|*Biomarkers 100 FKBP10 29801479 BMC Med. Genet. 2018 PMC5970456 10.1186/s12881-018-0579-8 1 1 0 126 *Osteogenesis Imperfecta|*RNA Splicing|Multiple Pterygium Syndrome, Autosomal Dominant|Arthrogryposis|Homozygote|Mutations|Tacrolimus Binding Proteins|Pedigree|Heredity 100 FKBP10 29673351 Respir. Res. 2018 PMC5909279 10.1186/s12931-018-0768-1 4 4 0 126 Humans|*Cell Movement|Idiopathic Pulmonary Fibrosis|*Lung|Fibroblasts|Extracellular Matrix|Cells, Cultured|Tacrolimus Binding Proteins|Signal Transduction|Collagen|FKBP10 protein, human 100 FKBP10 29512769 Int. J. Mol. Med. 2018 10.3892/ijmm.2018.3542 0 0 0 126 Humans|*Osteogenesis Imperfecta|Homozygote|Sequence Deletion|Serpins|Eye Proteins|Nerve Growth Factors|Heterozygote|*Chinese|Mutation|Tacrolimus Binding Proteins|Collagen Type I|*Genes, Regulator|Genotype|FKBP10 protein, human 100 FKBP10 29499418 Bone 2018 10.1016/j.bone.2018.02.029 5 0 0 126 Humans|*Osteogenesis Imperfecta|*Genotype-Phenotype Correlation|Heterozygote|*Asian Continental Ancestry Group|Phenotype|Mutation|Genotype|Sequencing, Next-Generation|Whole Exome Sequencing|Collagen Type I|Tacrolimus Binding Proteins|*Cohort Studies|FKBP10 protein, human 100 FKBP11 30221722 Mol Med Rep 2018 PMC6172375 10.3892/mmr.2018.9485 2 48 0 61 21 FLVCR2 30221345 Clin. Genet. 2018 10.1111/cge.13448 3 0 0 41 Humans|Child|*Intellectual Disability|*Phenotypes|Whole Exome Sequencing|Facies|Pedigree|Exome|Genetic Association Studies|Mutation|Alleles|*Rare Diseases|High-Throughput Nucleotide Sequencing|Epilepsy|Genomics|ALMS1 protein, human|Proteins|FLVCR2 protein, human|Receptors, Virus|Membrane Transport Proteins 22 FLVCR2 29500860 Mol Genet Genomic Med 2018 PMC6014450 10.1002/mgg3.376 2 1 0 41 Encephaloclastic Proliferative Vasculopathy|*Hydranencephaly|*Hydrocephaly|*Syndrome|*Vascular Diseases|Pena Shokeir syndrome, type 1|Arthrogryposis|Brain|Mutations|Membrane Transport Proteins|Alleles|Receptors, Virus 22 FMN1 30569497 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.60694 2 0 0 3571 Humans|Microphthalmia, syndromic 1|Syndactyly Cenani Lenz type|*Syndactyly|GREM1 protein, human|*Intercellular Signaling Peptides and Proteins|*Bone Morphogenetic Protein|*Adenomatous Polyposis Coli|APC protein, human|Adenomatous Polyposis Coli Protein|Homozygote|Phenotype|LDL-Receptor Related Proteins|Mutation|Pedigree|RNA Splicing|LRP4 protein, human 42 FMN1 30153818 BMC Genomics 2018 PMC6114738 10.1186/s12864-018-5002-5 7 3 0 3571 Animals|*Goat|hydrogen sulfite|Hair Follicles|*Sulfites|*Skin|Gene Expression Profiling|*Sequencing, Whole Genome|MicroRNAs|Gene Expression Regulation, Developmental|Genome|DNA Methylation|*Biological Phenomena 42 FMN1 29945573 BMC Cancer 2018 PMC6020382 10.1186/s12885-018-4609-x 9 16 0 3571 *DNA Methylation|CpG Islands|Adenoma|Colorectal Neoplasms|*Mutation|Promoter Regions, Genetic|*Exon|Biomarkers, Tumor|TP53 Genes|*Colon Cancer|Gene Expression Regulation, Neoplastic|DNA Mutational Analysis|RNA, Messenger 42 FMN1 29902190 PLoS ONE 2018 PMC6002036 10.1371/journal.pone.0198787 0 13 0 3571 *Saccharomyces cerevisiae|*NAD|*Flavins|4,6-dinitro-o-cresol|*Dinitrocresols|Saccharomyces cerevisiae Proteins|FAD pyrophosphatase|*Pyrophosphatases|Flavin-Adenine Dinucleotide|Flavin Mononucleotide|*Homeostasis|Mitochondria|riboflavin kinase|Phosphotransferases (Alcohol Group Acceptor) 42 FMN2 30510376 World J. Gastroenterol. 2018 PMC6262250 10.3748/wjg.v24.i44.5013 1 1 0 123 *Formins|Promoter Regions, Genetic|CpG Islands|DNA Methylation|Gene Expression Regulation, Neoplastic|Colorectal Neoplasms|*Carcinogenesis|Biomarkers, Tumor|Gene Silencing|Down-Regulation|Cell Line, Tumor 63 FMN2 30218017 Nat. Cell Biol. 2018 10.1038/s41556-018-0197-x 0 0 0 123 *Actins|*Formins|Microfilament Proteins|Actin Cytoskeleton|Cell Nucleus|Nuclear Proteins|Nerve Tissue Proteins 63 FMN2 30083988 Mol. Biol. Rep. 2018 10.1007/s11033-018-4260-2 4 1 0 123 Humans|*Osteoarthritis, Knee|*Wnt Signaling Pathway|Gene Frequency|SNPs|Alleles|*Epistasis, Genetic|Genetic Predisposition to Disease|beta Catenin|*Catenins|Genotype|CCN4 protein, human|CCN Intercellular Signaling Proteins|Asian Continental Ancestry Group|Case-Control Studies|Proto-Oncogene Proteins|Mexico 63 FMN2 29801487 BMC Med Genomics 2018 PMC5970458 10.1186/s12920-018-0362-x 0 0 0 123 Child|Humans|Autism Spectrum Disorder|Exome|Genetic Predisposition to Disease|DNA Copy Number Variations|Mutation|Neurodevelopmental Disorders|*Nucleotides 63 FMN2 29659741 Cereb. Cortex 2018 PMC6458913 10.1093/cercor/bhy073 0 11 0 123 Mice|Animals|*Formins|LRP6 protein, human|Low Density Lipoprotein Receptor-Related Protein-6|Wnt Signaling Pathway|beta Catenin|*Catenins|Wnt Proteins|Ubiquitination|*Lysosomes|E3 Ligase|FLNA protein, human|Filamin A|RHOA protein, human|rhoA GTP-Binding Protein|Adaptor Proteins, Signal Transducing|Protein Binding|Endocytosis|Proteolysis 63 FMN2 29626196 Leukemia 2018 PMC6170391 10.1038/s41375-018-0092-2 3 0 0 123 Child|Humans|*Transcriptome|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Mutation|DNA Methylation|High-Throughput Nucleotide Sequencing|Base Sequence|Diploidy|B-Lymphocytes|Cohort Studies|KCNT2 protein, human|Potassium Channels, Sodium-Activated 63 FMN2 29463849 Sci Rep 2018 PMC5820260 10.1038/s41598-018-20321-4 0 0 0 123 Cross-Sectional Studies|*Carcinoma, Renal Cell|Kidney Neoplasms|Von Hippel-Lindau Tumor Suppressor Protein|PBRM1 protein, human|Nuclear Proteins|Transcription Factors|Prognosis|Mutation|Gene Expression Regulation, Neoplastic|Neoplasm Staging|Cell Transformation, Neoplastic 63 FNDC1 30588242 J Cancer 2018 PMC6299387 10.7150/jca.27672 7 0 0 16 29 FNDC1 30402143 Exp Ther Med 2018 PMC6201048 10.3892/etm.2018.6731 1 0 0 16 Humans|*Stomach Neoplasms|FN1 protein, human|*Fibronectins|Prognosis|Immunohistochemistry|Kaplan-Meier Analysis|Adenocarcinoma|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Neoplasm Staging|RNA, Messenger|Real-Time Polymerase Chain Reaction|Blotting, Western|FNDC1 protein, human|Neoplasm Proteins 29 FNDC1 29649427 Exp. Cell Res. 2018 10.1016/j.yexcr.2018.04.007 3 15 0 16 Humans|FLT4 protein, human|*Vascular Endothelial Growth Factor Receptor-3|Vascular Endothelial Growth Factor C|*Endothelial Cells|Vascular Endothelial Growth Factor A|Lymphangiogenesis|*Signal Transduction|KDR protein, human|Vascular Endothelial Growth Factor Receptor-2|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|*G Protein|Phosphorylation|Cell Movement|Endocytosis|RNA Interference 29 FNDC1 29476074 Nat Commun 2018 PMC5824957 10.1038/s41467-018-03244-6 13 0 0 16 Adult|Humans|*Muscle, Skeletal|Satellite Cells, Skeletal Muscle|*Aging|Cell Proliferation|Cells, Cultured|*Mutagenesis|Gene Expression 29 FNIP1 30361061 Trends Biochem. Sci. 2018 PMC6324182 10.1016/j.tibs.2018.09.018 4 0 0 189 MTOR protein, human|*TOR Serine-Threonine Kinases|Tuberous Sclerosis Complex 1 Protein|Signal Transduction|Tuberous Sclerosis|Tumor Suppressor Proteins|Carrier Proteins|CCL26 protein, human|*Chemokine CCL26 44 FNIP1 30099721 Genes Genomics 2018 10.1007/s13258-018-0724-y 0 0 0 189 Humans|*Dendritic Cell Sarcoma, Interdigitating|*Whole Exome Sequencing|Immunohistochemistry|*Lymphoma, Non-Hodgkin|Soft Tissue Neoplasms|Sarcoma|Diagnosis, Differential|PTPRC protein, human|Leukocyte Common Antigens|Biomarkers, Tumor 44 FNIP1 29897930 PLoS ONE 2018 PMC5999084 10.1371/journal.pone.0197973 2 77 0 189 Humans|Mice|Animals|*mTORC1|Birt-Hogg-Dube Syndrome|*Kidney Neoplasms|FLCN protein, human|Tumor Suppressor Proteins|Renal Cell Carcinoma|Proto-Oncogene Proteins|*Kidney|MTOR protein, human|TOR Serine-Threonine Kinases|*Cysts|Disease, Polycystic Kidney|Carrier Proteins|*Cytoplasm|Pneumothorax|Lung Diseases|Mutations|Phosphorylation 44 FNIP1 29848618 J. Cell Biol. 2018 PMC6080935 10.1083/jcb.201712177 9 41 0 189 *Amino Acids|*Folliculin|RRAGC protein, human|Monomeric GTP-Binding Proteins|RRAGA protein, human|FLCN protein, human|*Tumor Suppressor Proteins|*Lysosomes|*Proto-Oncogene Proteins|Mechanistic Target of Rapamycin Complex 1|Multiprotein Complexes|TOR Serine-Threonine Kinases|GTPase-Activating Proteins|Signal Transduction|Carrier Proteins|Protein Binding|Guanosine Diphosphate|Protein Multimerization 44 FNIP1 29774133 Oncotarget 2018 PMC5955167 10.18632/oncotarget.25164 3 16 0 189 Humans|*Angiomyolipoma|*Kidney Neoplasms|Birt-Hogg-Dube Syndrome|Tumor Suppressor Proteins|Proto-Oncogene Proteins|Mutations, Germline|*Molecular Chaperones|Mutation|*Lipoma|*Hamartoma 44 foxd4 30252597 Cancer Biol. Ther. 2018 PMC6301805 10.1080/15384047.2018.1480291 1 1 0 58 Humans|*Colorectal Cancer|CDH1 protein, human|*Cadherins|Epithelial-Mesenchymal Transition|Transcription Factor|*Antigens, CD|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|Up-Regulation|Cell Proliferation|Transcriptional Activation|*Colonic Neoplasms|Signal Transduction|*Neoplastic Processes|Promoter Regions, Genetic 27 foxd4 29777416 Fish Physiol. Biochem. 2018 10.1007/s10695-018-0519-8 3 0 0 58 Animals|Female|Male|*Sex Differentiation|*Takifugu|*Gonad|Ovary|Testis|Transcriptome|Transcriptome Analysis|Germ Cells|Cichlids|Gene Expression Regulation, Developmental|mRNA|Cell Differentiation 27 foxd4 29307282 Exp. Biol. Med. (Maywood) 2018 PMC6022930 10.1177/1535370217751073 0 0 0 58 Rats|Animals|*Anorectal Malformations|Ethylenethiourea|Anus, Imperforate|Rats, Wistar|Anus|*Transcription Factor|Rectum|Western Blot|Real-Time PCR, Quantitative|Digestive Tract|Gene Expression Regulation, Developmental|*Endoderm|Immunohistochemistry|RNA, Messenger|Animal Models|Foxd3 protein, rat|Repressor Proteins|Forkhead Transcription Factors 27 FOXE3 30479708 J Ophthalmic Vis Res 2018 PMC6210873 10.4103/jovr.jovr_193_17 0 0 0 58 Microphthalmos|Homeodomain Proteins|Aphakia|Forkhead Transcription Factors|Amino Acid Sequence|Mutation 110 FOXE3 30078984 Mol. Vis. 2018 PMC6054834 2 0 0 58 Humans|*Cataract|*Mutation|*Chinese|DNA Mutational Analysis|Connexins|Pedigree|Genes, Dominant|Eye Proteins|Base Sequence|Haplotypes 110 FOXE3 29921154 J. Int. Med. Res. 2018 PMC6124292 10.1177/0300060518774687 0 9 0 58 Animals|Mice|CASP8 protein, human|*Caspase 8|CASP3 protein, human|*Caspase 3|*Lens, Crystalline|*Apoptosis|*Signal Transduction|Homeodomain Proteins|Anterior segment mesenchymal dysgenesis|Eye Abnormalities|Microphthalmia|Cell Proliferation|Mice, Knockout|Eye Proteins|Forkhead Transcription Factors|Tumor Suppressor Proteins|Organogenesis 110 FOXE3 29878917 Cornea 2018 10.1097/ICO.0000000000001655 1 0 0 58 Humans|*Microphthalmos|Sclerocornea|*Corneal Diseases|*Aphakia|*Cornea|Eye Abnormalities|Homozygote|Heterozygote|Phenotype|Mutation|Amino Acid Sequence|Forkhead Transcription Factors|Mexico|FOXE3 protein, human 110 FOXE3 29752539 Hum. Genet. 2018 10.1007/s00439-018-1890-3 0 0 0 58 Animals|Humans|*Zebrafish|*Lens, Crystalline|*Cataract|Eye Proteins|Homeodomain Proteins|Eye Abnormalities|Forkhead Transcription Factors|*Lenses|Amino Acid Sequence|FOXE3 protein, human 110 FOXE3 29713869 Hum. Genet. 2018 PMC6020821 10.1007/s00439-018-1884-1 4 1 0 58 Animals|Humans|*Zebrafish|*Lens, Crystalline|*Cataracts|Microphthalmia|Aphakia|Homozygotes|Eye Proteins|Sclerocornea|Corneal Diseases|Cornea|Forkhead Transcription Factors|Mutation|Phenotype|*Lenses|FOXE3 protein, human 110 FOXE3 29660784 J. Neurosci. Res. 2018 PMC6191383 10.1002/jnr.24245 1 2 0 58 *Neural Crest|Eye Abnormalities|Genes, Homeobox|Anterior Eye Segment|TFAP2B protein, human|Transcription Factor AP-2|Homeodomain Proteins|Mesenchyme|Organogenesis|Gene Expression Regulation, Developmental|Cell Movement|Signal Transduction|Forkhead Transcription Factors|Mutations 110 FOXE3 29482575 Genome Biol. 2018 PMC5828090 10.1186/s13059-018-1400-x 14 1 0 58 Mice|Female|Humans|Animals|*Genome Editing|*Clustered Regularly Interspaced Short Palindromic Repeats|CRISPR-Cas Systems|RNA, Guide|*Endonucleases|*Genome|*Fallopian Tubes|*Oviducts|Zygotes|Electroporation|Microinjection|*Germ Line|Ribonucleoproteins|Embryo, Mammalian|Gonads 110 FOXE3 29461140 Ophthalmic Genet. 2018 10.1080/13816810.2018.1436184 1 0 0 58 Humans|*Anophthalmos|*Microphthalmos|*Eye|Coloboma|Homeodomain Proteins|Eye Proteins|Mutation|Transcription Factors|SOXB1 Transcription Factors|Phenotype|Genes, Developmental|India 110 FOXE3 29317205 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.01.031 1 0 0 58 Cyclic Nucleotide Phosphodiesterases, Type 6|Retinal Degeneration|Electroretinography|Mutation 110 FOXE3 29314435 Hum. Mutat. 2018 PMC5839989 10.1002/humu.23395 8 0 0 58 Humans|Animals|Cataracts, Congenital, with Sensorineural Deafness, Down Syndrome-Like Facial Appearance, Short Stature, and Mental Retardation|*Cataracts|Microphthalmia|Lens, Crystalline|*Mutation|Anterior segment mesenchymal dysgenesis|Eye Abnormalities|*Eye|Homeodomain Proteins|Aphakia|Transcription Factors|Intellectual Disability|Facies|Hearing Loss, Sensorineural|Phenotype|Growth Disorders|HSF4 protein, human|Heat Shock Transcription Factors 110 FOXI3 30467319 Sci Rep 2018 PMC6250667 10.1038/s41598-018-35390-8 1 0 0 37 *Protein Phosphatase 2|Phosphorylation|Forkhead Box Proteins|Protein Binding|Amino Acid Sequence|Protein Domains|*Biochemical Phenomena|Cell Nucleus 30 FOXI3 30018953 Front Cell Dev Biol 2018 PMC6038025 10.3389/fcell.2018.00069 5 1 0 37 Forkhead Transcription Factors|Morphogenesis|Cancer|Cell Differentiation|Embryogenesis|Protein Domains|Apoptosis|DNA Sequence 30 FOXL1 29975848 J. Dent. Res. 2018 PMC6262265 10.1177/0022034518785336 5 0 0 224 Humans|*Cleft Palate|*Hedgehog Proteins|*Osteogenesis|Palate|Mesenchyme|Bone Morphogenetic Protein|Wnt Pathways|Neural Crest|Gene Expression Regulation, Developmental|Transcription Factors, Fox|Cell Proliferation|SOSTDC1 protein, human|Proteins|FOXL1 protein, human 103 FOXL1 29805604 Oncol Lett 2018 PMC5950509 10.3892/ol.2018.8405 1 0 0 224 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Nephrectomy|Kaplan-Meier Analysis|Disease-Free Survival|Prognosis|Proportional Hazards Models|Neoplasm Grading|Biomarkers, Tumor|Cohort Studies|Forkhead Transcription Factors 103 FOXL1 29720649 Nature 2018 PMC5966331 10.1038/s41586-018-0084-4 67 1 0 224 Animals|*Telocytes|Intestinal Epithelium|Stem Cells|Cell Differentiation|Wnt Proteins|Intestines|Wnt Signaling Pathway|Stem Cell Niche|Epithelial Cells|Cell Proliferation 103 FOXL1 29346513 Carcinogenesis 2018 10.1093/carcin/bgy005 3 0 0 224 *APOBEC-1|*Cancer|*Prognosis|INDEL Mutation|*Reading Frames|Genome|Mutations|Proteins 103 FOXN2 30320371 Int. 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Oncol. 2018 10.3892/ijo.2018.4591 2 2 0 138 Humans|*Colorectal Cancer|*Signal Transduction|HLTF protein, human|*Transcription Factors|Cell Movement|Neoplasm Invasiveness|HCT116 Cells|Epithelial-Mesenchymal Transition|SMAD4 protein, human|Smad4 Protein|Gene Expression Regulation, Neoplastic|*Transforming Growth Factor|Cell Line, Tumor|Transforming Growth Factor beta|MicroRNAs|Cell Proliferation|*Colonic Neoplasms|Upregulation 28 FOXN2 29805604 Oncol Lett 2018 PMC5950509 10.3892/ol.2018.8405 1 0 0 138 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Nephrectomy|Kaplan-Meier Analysis|Disease-Free Survival|Prognosis|Proportional Hazards Models|Neoplasm Grading|Biomarkers, Tumor|Cohort Studies|Forkhead Transcription Factors 28 FOXN2 29396548 Cell Death Differ. 2018 PMC6113220 10.1038/s41418-017-0055-6 4 4 0 138 ribosomal protein S6 kinase, 90kDa, polypeptide 3|UBB protein, human|*Ubiquitin|*Ribosomal Protein S6 Kinases, 90-kDa|*Cell Transformation, Neoplastic|beta-Transducin Repeat-Containing Proteins|*Tumorigenesis|Proteolysis|Phosphorylation|Ubiquitination|Proteasome Endopeptidase Complex|*Lung Cancer|Protein Processing, Post-Translational|Protein Binding|Cell Line, Tumor|Radiosensitivity|RNA, Small Interfering|*Ligases 28 FOXN4 30240734 iScience 2018 PMC6147019 10.1016/j.isci.2018.05.014 2 15 0 65 Humans|Animals|*Chromatin|*Chromatin Assembly and Disassembly|Neurogenesis|Paired Box Transcription Factors|Homeodomain Proteins|Transcription Factor PAX6|Repressor Proteins|Eye Proteins|Neurons|Cerebral Cortex 54 FOXN4 29719254 Cell Rep 2018 PMC5946716 10.1016/j.celrep.2018.04.002 11 1 0 65 Humans|Animals|Mice|*Gene Regulatory Networks|Hedgehog Proteins|Zebrafish|Zebrafish Proteins|*Nerve Regeneration|Ependymoglial Cells|Retina|Cells, Glial|Basic Helix-Loop-Helix Transcription Factors|Signal Transduction|Stem Cell|Cell Proliferation|Transcription Factors|MicroRNAs|SHH protein, human|Shh protein, mouse 54 FOXN4 29536689 Zhongguo Gu Shang 2018 10.3969/j.issn.1003-0034.2018.02.014 0 0 0 65 *Transcriptome|*Osteoarthritis|Gene Expression Profiling|Gene Regulatory Networks|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation|Synovial Membrane|Transcription Factors|*Complement Factor B|*Bone|3'-(1-butylphosphoryl)adenosine 54 FRG2 30549325 Eur. J. Neurosci. 2018 10.1111/ejn.14303 0 0 0 17 *Repetition Priming|Bayes Theorem|*Event-Related Potentials|*Brain|Perception, Face|Electroencephalography|Fusiform Gyrus|Recognition, Psychology|Reaction Time|Pattern Recognition, Visual|Cortex, Prefrontal|Occipital Lobe|Face|Neuropsychological Tests 47 FRG2 30518104 Molecules 2018 PMC6320820 10.3390/molecules23123194 9 0 0 17 KDM1A protein, human|Histone Demethylases|Leukemia, Myeloid, Acute|Histones|Cell Proliferation|Antineoplastic Agents|Enzyme Inhibitors|Cell Line, Tumor|Cell Differentiation|Prognosis 47 FRG2 30479351 Sci Rep 2018 PMC6258675 10.1038/s41598-018-35575-1 1 0 0 17 Optical Tweezers|Optics and Photonics|*Physical Phenomena 47 FRMD4A 30214071 Genet. Med. 2018 PMC6986385 10.1038/s41436-018-0140-3 9 0 0 33 Humans|*Microcephaly|Dwarfism|Homozygote|Exome|Pedigree|Phenotype|Facies|Mutation|*Genomics 26 FRMD4A 29860346 Int J Epidemiol 2018 PMC6124615 10.1093/ije/dyy091 19 2 0 33 Humans|Adult|Male|Female|Middle Aged|Pregnancy|*DNA Methylation|*Smoke|*B-DNA|Maternal Exposure|CpG Islands|Prenatal Exposure Delayed Effects|Epigenesis, Genetic|Cohort Studies|Smoking|Genome-Wide Association Study|Fetal Blood|*Biomarkers|*Tobacco|*Protein Processing, Post-Translational 26 Frzb 30256452 Glia 2018 PMC6517278 10.1002/glia.23515 3 2 0 374 Mice|Animals|*Olfactory Bulb|*Axons|Olfactory Epithelium|Olfactory Nerve|Neuroglia|*Smell|Olfactory Receptor Neurons|Neurogenesis|Cell Differentiation|Gonadotropin Releasing Hormone|Prosencephalon|Cell Movement|*B Cells 205 Frzb 30238381 Clin. Rheumatol. 2018 10.1007/s10067-018-4298-5 2 0 0 374 Humans|*Wnt Signaling Pathway|*Scleroderma, Diffuse|Wnt Proteins|Frizzled Receptors|Gene Expression|RNA, Messenger 205 Frzb 30209221 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6166843 10.1073/pnas.1812117115 3 31 0 374 Animals|Xenopus Proteins|Xenopus laevis|Organizers, Embryonic|Low Density Lipoprotein Receptor-Related Protein-6|Wnt Proteins|Wnt Signaling Pathway|beta Catenin|Embryo, Nonmammalian|Gene Expression Regulation, Developmental 205 Frzb 30152531 Anim. Genet. 2018 10.1111/age.12715 0 0 0 374 Horses|Animals|Poland|*Osteochondrosis|*Breeding|Horse Diseases|Hock|Genotype|SNPs|Quantitative Trait Loci|*Genetic Selection|Phenotype|Microsatellite Repeats|*Sport 205 Frzb 30123421 Oncotarget 2018 PMC6089551 10.18632/oncotarget.25741 3 13 0 374 *Thyroid Hormone Receptor|*Intestinal Neoplasms|*Signal Transduction|Thyroid Hormone Receptors alpha|*Gene Expression Regulation|*Thyroid Gland|*Cell Nucleus|beta Catenin|Intestinal Mucosa|Transcription Factor|Thyroid Hormones 205 Frzb 30111857 Sci Rep 2018 PMC6093887 10.1038/s41598-018-29789-6 6 3 0 374 Humans|Quality of Life|Genome-Wide Association Study|*Quadriceps Muscle|*Chronic Obstructive Pulmonary Disease|*Mitochondria|Muscle, Skeletal|Lung|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|*Extracellular Matrix|POSTN protein, human|Cell Adhesion Molecules|PANX1 protein, human|Nerve Tissue Proteins|Connexins 205 Frzb 30083988 Mol. Biol. Rep. 2018 10.1007/s11033-018-4260-2 4 1 0 374 Humans|*Osteoarthritis, Knee|*Wnt Signaling Pathway|Gene Frequency|SNPs|Alleles|*Epistasis, Genetic|Genetic Predisposition to Disease|beta Catenin|*Catenins|Genotype|CCN4 protein, human|CCN Intercellular Signaling Proteins|Asian Continental Ancestry Group|Case-Control Studies|Proto-Oncogene Proteins|Mexico 205 FUBP1 30500954 Nucleic Acids Res. 2018 PMC6265458 10.1093/nar/gky756 1 4 0 327 Humans|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|*Cell Proliferation|FUBP1 protein, human|DNA-Binding Proteins|*Oncogenes|Gene Expression Regulation, Leukemic|Proto-Oncogene Proteins c-kit|Oncogene Proteins, Fusion|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Translocation, Genetic|RNA-Binding Proteins|Cell Line, Tumor|Apoptosis|Chromatin|*Regulatory Regions|Protein Binding 171 FUBP1 30470264 Acta Neuropathol Commun 2018 PMC6251173 10.1186/s40478-018-0633-y 7 0 0 327 Humans|*High-Throughput Nucleotide Sequencing|*Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Glioblastoma|Mutations|PTEN protein, human|PTEN Phosphohydrolase|Promoter Regions, Genetic|Biomarkers, Tumor|ErbB Receptors|DNA Copy Number Variations|Cohort Studies 171 GABRD 30532739 Front Endocrinol (Lausanne) 2018 PMC6265503 10.3389/fendo.2018.00703 7 4 0 33 Humans|Female|Animals|Mice|*Depression, Postpartum|*Depression|*Neurosteroids|Pituitary-Adrenal System|Hypothalamo-Hypophyseal System|Corticosterone|Corticotropin-Releasing Hormone|Paraventricular Hypothalamic Nucleus|Stress, Psychological|Behavior, Animal|Postpartum 105 GABRD 30389723 J. Pharmacol. Exp. Ther. 2018 PMC6304376 10.1124/jpet.118.252403 1 3 0 33 Humans|*Etomidate|Receptors, GABA-A|gamma-Aminobutyric Acid|Hypnotics and Sedatives|Patch-Clamp Techniques|HEK293 Cells 105 GABRD 30295757 Cardiovasc. Res. 2018 10.1093/cvr/cvy248 0 2 0 33 Animals|Humans|Female|*Stroke|Middle Cerebral Artery Occlusion|Neurons|Neuroprotective Agents|*Brain Injury|Brain|Progesterone|Contraceptives, Oral|Progestins|Cells, Cultured|Disease Models, Animal|drospirenone|Androstenes 105 GABRD 30191083 Tremor Other Hyperkinet Mov (N Y) 2018 PMC6125735 10.7916/D8JW9X9K 2 5 0 33 Animals|Mice|Humans|*Harmaline|*Tremor|*gamma-Aminobutyric Acid|GABA Agonists|Receptors, GABA-A|Cerebellum|Neurons|Isoxazoles|Essential Tremor|Mice, Knockout 105 GABRG1 30272454 J. Proteome Res. 2018 10.1021/acs.jproteome.8b00406 2 0 0 26 Humans|*Proteomics|*Transcriptome|*Antibodies|Proteome|Sequence Analysis, RNA|Gene Expression Profiling|*Computational Biology|Immunohistochemistry|*Extracellular Space 48 GABRP 29445327 Front Cell Neurosci 2018 PMC5797743 10.3389/fncel.2018.00010 0 4 0 19 40 GAGE1 30297572 Niger J Clin Pract 2018 10.4103/njcp.njcp_73_18 0 0 0 20 Humans|Male|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Testis|CTAG1B protein, human|*Antigens, Neoplasm|Liver Cirrhosis|Biomarkers, Tumor|*Membrane Proteins|Fluorescent Antibody Technique, Indirect|Autoantibodies|Enzyme-Linked Immunosorbent Assay 48 GAGE1 30103946 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.07.164 20 5 0 20 Humans|Animals|*Nonsmall Cell Lung Cancer|*Upregulation|*RNA, Circular|Lung Neoplasms|*Prognosis|*Disease Progression|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Oncogenesis|Cell Line, Tumor|Apoptosis|*Transcriptional Activation|Oncogenes|Lymphatic Metastasis|MIRN1287 microRNA, human 48 GAGE1 30006881 Bull. Exp. Biol. Med. 2018 10.1007/s10517-018-4175-x 0 0 0 20 Humans|Male|Female|*Testis|MAGEA3 protein, human|Antigens, Neoplasm|Neoplasm Proteins|Melanoma-Specific Antigens|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Membrane Proteins|*Activation, Transcription|*Transcription Factors|Real-Time Polymerase Chain Reaction|Neoplasms|MAGEA4 protein, human|MAGEB2 protein, human|MageA2 protein, human 48 GAGE1 29577858 Curr. Mol. Med. 2018 10.2174/1566524018666180322162145 1 0 0 20 Male|*Squamous Cell Carcinoma of Head and Neck|*Prognosis|*Testis|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Antigens, Neoplasm|Neoplasm Proteins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Immunotherapy 48 GALM 30579737 Can J Diabetes 2018 10.1016/j.jcjd.2018.11.003 2 0 0 50 Adult|Humans|*Diabetic Ketoacidosis|*Retrospective Studies|Canada|Diabetes Mellitus, Type 1|Hypoglycemic Agents|Insulin|*Hospitals, Teaching|Fluid Therapy|Tertiary Care Centers 173 GALM 30451973 Genet. Med. 2018 10.1038/s41436-018-0340-x 3 0 0 50 Humans|*Galactosemias|UDPglucose 4-Epimerase|Galactose|Carbohydrate Epimerases|Carbohydrate Metabolism 173 GBX1 29945667 Neural Dev 2018 PMC6020313 10.1186/s13064-018-0112-y 1 19 0 17 Animals|*Zebrafish|*Hindbrain|Zebrafish Proteins|Transcription Factors|Embryo, Nonmammalian|Body Patterning|Homeodomain Proteins|Gene Expression Regulation, Developmental|Fibroblast Growth Factors|Retinoic Acid|Morphogenesis|Nerve Tissue Proteins|In Situ Hybridization|MafB Transcription Factor|Hepatocyte Nuclear Factor 1-beta|Neurons|*Gene Expression|Signal Transduction 34 GBX1 29289755 Differentiation 2018 10.1016/j.diff.2017.12.005 0 3 0 17 Animals|*Zebrafish|*Genes, Homeobox|In Situ Hybridization, Fluorescence|*Gastrulation|Zebrafish Proteins|*Telencephalon|Homeodomain Proteins|Gene Expression Regulation, Developmental|Body Patterning|Rhombencephalon|Animals, Genetically Modified|Prosencephalon|Mesencephalon|Neurogenesis|Signal Transduction|Transcriptional Activation|gbx2 protein, zebrafish 34 GCM1 30526365 Stem Cells Dev. 2018 10.1089/scd.2018.0068 1 3 0 325 Pregnancy|Female|Mice|Animals|*Trophoblasts|*Cell Differentiation|*Stem Cells|Homeodomain Proteins|Transcription Factors|CDX2 Transcription Factor|Gene Expression Regulation, Developmental|*Androgens|Blastocysts|Signal Transduction|Cell Proliferation|Placentation|Embryo, Mammalian|FGF4 protein, human|Fibroblast Growth Factor 4|Extracellular Signal Regulated Kinases|Giant Cells 162 GCM1 29979633 FASEB J. 2018 10.1096/fj.201800124R 0 8 0 325 Humans|Female|Pregnancy|*Trophoblasts|*Placenta|Placental Development|Decidua|frizzled related protein-3|WNT10B protein, human|*Wnt Proteins|*Proto-Oncogene Proteins|Embryo Implantation|Stromal Cells|Cell Migration|Endometrium|Nuclear Proteins|Pre-Eclampsia|Transcription Factors|Cells, Cultured|*Cells, Glial|FZD7 protein, human 162 GCM1 29755409 Front Endocrinol (Lausanne) 2018 PMC5932191 10.3389/fendo.2018.00195 0 10 0 325 Horses|Animals|Female|Pregnancy|*Chorionic Gonadotropin, beta Subunit, Human|Trophoblast|Transcription Factors|Placenta|Nuclear Proteins|Homeodomain Proteins|Transcription, Genetic|Promoter Regions, Genetic|*Neuroglia|*B Cells|Cell Differentiation|Protein Binding 162 GCM1 29743241 J. 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Funct. 2018 10.1002/cbf.3371 0 10 0 20 Humans|*Esophageal Squamous Cell Carcinoma|*Epithelial-Mesenchymal Transition|*Esophageal Neoplasms|CDH1 protein, human|N-Cadherin|Neoplasm Invasiveness|Carcinoma, Squamous Cell|Vimentin|Antigens, CD|Cell Movement|Prognosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Biomarkers, Tumor|Disease Progression|GCNT2 protein, human|N-Acetylhexosaminyltransferases 37 GCNT2 30564237 Front Immunol 2018 PMC6288978 10.3389/fimmu.2018.02839 2 0 0 20 LGALS9 protein, human|*Galectin|*B-Lymphocytes|*Glycans|Glycosylation|Signal Transduction|Immunity, Innate|Glycosyltransferases|Cell Differentiation 37 GCNT2 30135430 Nat Commun 2018 PMC6105653 10.1038/s41467-018-05795-0 5 40 0 20 N-Acetylhexosaminyltransferases|*Melanoma|*Glycans|N-Acetylglucosaminyltransferases|Glycosylation|Cell Movement|Cell Line, Tumor|Signal Transduction|Integrins|Downregulation|Cell Survival 37 GCNT2 30120234 Nat Commun 2018 PMC6098069 10.1038/s41467-018-05770-9 11 55 0 20 Humans|CD22 protein, human|Sialic Acid Binding Ig-like Lectin 2|Receptors, Antigen, B-Cell|*Signal Transduction|B Cells|LGALS9 protein, human|*Galectins|Germinal Center|PTPRC protein, human|Leukocyte Common Antigens|Lymphocyte Activation|Protein Tyrosine Phosphatase, Non-Receptor Type 6|src-Family Kinases|Phosphorylation|*Glycans 37 GCNT2 29982135 Theriogenology 2018 10.1016/j.theriogenology.2018.06.021 2 0 0 20 37 GCNT2 29914532 Orphanet J Rare Dis 2018 PMC6006596 10.1186/s13023-018-0828-0 6 0 0 20 Child|Humans|*Cataract|Crystallins|*Chinese|DNA Mutational Analysis|Pedigree|Mutation, Missense|Mutation 37 GCNT2 29794791 Medicine (Baltimore) 2018 PMC6392713 10.1097/MD.0000000000010871 0 6 0 20 Adult|Humans|*Mycosis Fungoides|Cutaneous T Cell Lymphoma|Sezary Syndrome|Skin Neoplasms|Biomarkers, Tumor|Leukemia-Lymphoma, Adult T-Cell|Biopsies|Gene Expression Profiling|REG1A protein, human|Lithostathine 37 GCNT2 29377145 J. Med. Primatol. 2018 10.1111/jmp.12332 0 0 0 20 Animals|Chlorocebus aethiops|*Cataract|Pedigree|Mutation, Missense|*Breeding 37 GIGYF2 30564305 Mol Autism 2018 PMC6293633 10.1186/s13229-018-0247-z 9 0 0 191 Humans|*Autistic Disorder|Exome|Autism Spectrum Disorder|Mutation|Genetic Predisposition to Disease|Genotype-Phenotype Correlations|Databases, Genetic|Cohort Studies|China 64 GIGYF2 30245141 Rev. Neurol. 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Med. J. 2018 PMC6278198 10.4103/0366-6999.246061 0 3 0 103 Mice|Animals|*Glucocorticoids|*Asthma|Receptors, Glucocorticoid|Familial Glucocorticoid Deficiency 1|Dual Specificity Phosphatase 1|*Steroid Metabolism, Inborn Errors|p38 Mitogen-Activated Protein Kinases|Phosphorylation|Gene Expression 47 GLCCI1 30256538 Int Forum Allergy Rhinol 2018 10.1002/alr.22220 0 0 0 103 Humans|*Sinusitis|Rhinitis|Endoscopy|*Chronic Disease|Inflammation|*Chinese|Postoperative Period|Glucocorticoids|China 47 GLCCI1 30229311 Surg. Today 2018 10.1007/s00595-018-1717-9 0 1 0 103 *Glucocorticoids|*Lung Transplantation|*Total Lung Capacity|*Single Nucleotide Polymorphism|Primary Graft Dysfunction|Receptors, Glucocorticoid|Genotype|*Module, Gene|Risk Factors|Nucleotides 47 GLCCI1 29981236 Med. Sci. Monit. 2018 PMC6069539 10.12659/MSM.908814 0 9 0 103 Humans|*Glucocorticoids|*Rhinitis, Allergic, Seasonal|*Corticosteroids|Glucocorticoid Receptor Deficiency|Receptors, Glucocorticoid|*Chinese|*Administration, Intranasal|Genotype|Asthma|Administration, Inhalation|HNF1A protein, human|*Hepatocyte Nuclear Factor 1-alpha|Polymorphism, Single Nucleotide 47 GLCCI1 29384926 Medicine (Baltimore) 2018 PMC6392942 10.1097/MD.0000000000009442 3 4 0 103 Humans|*Corticosteroids|*Asthma|Genotype|Receptors, Glucocorticoid|Glucocorticoids|*Chinese|Administration, Inhalation|Forced Expiratory Volume|Single Nucleotide Polymorphisms|Respiratory Function Tests|Allele|Dexamethasone 47 GLCCI1 29345236 J Investig Allergol Clin Immunol 2018 10.18176/jiaci.0229 4 2 0 103 Humans|Genome-Wide Association Study|*Corticosteroids|*Asthma|Receptors, Glucocorticoid|Administration, Inhalation|Glucocorticoids|Genotype|Polymorphism, Single Nucleotide 47 GLDN 29473973 J. Bone Miner. Res. 2018 10.1002/jbmr.3412 8 0 0 88 Humans|*Genome-Wide Association Study|*Quantitative Trait Loci|*Bone Density|*Osteoclasts|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Linkage Disequilibrium|Osteoporosis|Bioinformatics 30 GLIPR2 29504907 BMC Genomics 2018 PMC5836836 10.1186/s12864-018-4477-4 13 17 0 52 *Epithelial-Mesenchymal Transition|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Colonic Neoplasms|Up-Regulation|RNA, Messenger 21 GLIPR2 29442320 Adv. Exp. Med. Biol. 2018 10.1007/978-981-10-7311-3_7 0 0 0 52 Animals|Xenopus laevis|Zinc Finger|Xenopus Proteins|Transcription Factors|Neural Crest|Homeodomain Proteins|Body Patterning|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Gastrula|Nervous System|Cell Differentiation 21 glis1 30544251 Nucleic Acids Res. 2018 PMC6380961 10.1093/nar/gky1240 4 0 0 33 Mice|Animals|AHR protein, human|*Aryl Hydrocarbon Receptor|*Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|Osteoblasts|Adipocytes|Osteogenesis|Mesenchymal Stem Cells|Cell Lineage|Multipotent Stem Cells|Chromatin|Gene Regulatory Networks|PPAR gamma 45 glis1 30404192 Int J Mol Sci 2018 PMC6274871 10.3390/ijms19113489 0 0 0 33 Humans|Mice|Animals|*Mesenchymal Stem Cells|Hematopoietic Stem Cell Transplantation|Transplantation, Autologous|Induced Pluripotent Stem Cells|Cellular Reprogramming|Cell Differentiation|GKLF protein|Kruppel-Like Transcription Factors|Octamer Transcription Factor-3|Nanog Homeobox Protein|Embryonic Stem Cells|Adipose Tissue|SOXB1 Transcription Factors|Homeodomain Proteins|Cells, Cultured|Transfections|Gene Expression Profiling|Fibroblasts 45 glis1 30239619 Carcinogenesis 2018 PMC6292413 10.1093/carcin/bgy122 4 0 0 33 Humans|*African Americans|Microsatellite Instability|Colorectal Cancer|MutL Protein Homolog 1|Proto-Oncogene Proteins B-raf|DNA Methylation|Mutation|ras Proteins|Adenomatous Polyposis Coli Protein|Exome|Chromosome Stability|Nuclear Proteins|Phenotype|Promoter Regions, Genetic|Wnt Signaling Pathway|Adaptor Proteins, Signal Transducing|DNA Copy Number Variations|TET1 protein, human 45 glis1 30120295 Sci Rep 2018 PMC6098023 10.1038/s41598-018-30784-0 5 0 0 33 Mice|Animals|Induced Pluripotent Stem Cells|POU5F1 protein, human|Octamer Transcription Factor-3|Cellular Reprogramming|Embryonic Stem Cells|Cell Differentiation|*Pancreas|Gene Expression Profiles|Cells, Cultured|Transfection|RNA|Transcription Factors|Teratoma|Promoter Regions, Genetic 45 glis1 30033902 Zygote 2018 10.1017/S0967199418000175 1 0 0 33 Cattle|Sheep|Mice|Animals|*Transcription Factors|*Preimplantation Embryos|Morula|Mammalian Embryos|Embryogenesis|Oocytes|Gene Expression Regulation, Developmental|Octamer Transcription Factor-3|Cell Differentiation|RNA, Messenger|Zfp281 protein, mouse 45 glis1 29779043 Cell. 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Neurol. 2018 10.1016/j.expneurol.2018.04.008 0 0 0 125 Animals|Mice|Humans|*Glia Maturation Factor|*Gliosis|*Zebrafish|*Traumatic Brain Injury|Astrocytes|Glial Fibrillary Acidic Protein|*Inflammation|Telencephalon|Microglia|Disease Models, Animal 26 GMFB 29445286 Neuropsychiatr Dis Treat 2018 PMC5810533 10.2147/NDT.S157099 3 30 0 125 *Glia Maturation Factor|Cell Differentiation|RNA, Messenger|Neurodegenerative Diseases|Upregulation|Apoptosis|Signal Transduction|Colony-Stimulating Factor, Granulocyte-Macrophage|Neurons 26 GOLGA3 29467256 Mol. Biol. Cell 2018 PMC5896932 10.1091/mbc.E17-11-0622 2 31 0 189 Humans|*Protein Transport|ADP-Ribosylation Factor 1|Golgi Apparatus|trans-Golgi Network|Guanine Nucleotide Exchange Factors|*Cell Movement|HeLa Cells 46 GPR158 30593799 Gastroenterology 2018 PMC6788806 10.1053/j.gastro.2018.12.014 1 0 0 90 Humans|*Hepacivirus|*Genome-Wide Association Study|*Hepatitis C|Interferon|Antiviral Agents|Interleukins|Hepatitis C, Chronic|Genotype|Polymorphism, Single Nucleotide|Viral Load|Remission, Spontaneous|Major Histocompatibility Complex 33 GPR158 30546127 Neuropsychopharmacology 2018 PMC6333837 10.1038/s41386-018-0238-y 2 1 0 90 33 GPR158 30355501 Cell Rep 2018 10.1016/j.celrep.2018.09.077 5 3 0 90 33 GPR158 30315127 J. 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Behav. 2018 10.1016/j.physbeh.2018.12.015 0 0 0 202 Animals|Humans|Adult|Male|NR2B NMDA receptor|N-methyl D-aspartate receptor subtype 2A|*Receptors, N-Methyl-D-Aspartate|*Healthy Volunteers|Working Memory|*Lymphocytes|Brain|Protein Subunits|mRNA|Executive Function|Cognition 70 GRIN3A 30338293 Neurol Genet 2018 PMC6186025 10.1212/NXG.0000000000000271 1 1 0 202 Genome-Wide Association Study|Genetic Predisposition to Disease|Parkinson Disease|Polymorphism, Single Nucleotide|Genotype 70 GRIN3A 30176218 Exp. 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Cell Biol. 2018 PMC6314548 10.1083/jcb.201805016 10 4 0 276 *Dyneins|*Brain-Derived Neurotrophic Factor|tropomyosin-related kinase-B, human|Receptor, trkB|*Neurons|*Endosomes|*Protein Transport|Axonal Transport|*Signal Transduction|Hippocampus|Dendrites|Axons|Cytoplasmic Dyneins|*Cell Movement|Microtubule-Associated Proteins|Microtubules|Membrane Glycoproteins|Cells, Cultured 33 HOOK3 29515126 Nat Commun 2018 PMC5841405 10.1038/s41467-018-03412-8 0 20 0 276 Humans|*Dynactin Complex|*Dyneins|Cytoplasmic Dyneins|Microtubules|Microtubule-Associated Proteins|Biological Transport|Carrier Proteins|Protein Binding|Cell Movement|Lysosomes|HeLa Cells|*Ion Transport|hook3 protein, human 33 HOOK3 29420470 Nature 2018 PMC5988349 10.1038/nature25462 59 19 0 276 *Dynactin Complex|*Dyneins|*Cryoelectron Microscopy|Microtubule|Microtubule-Associated Proteins|Cytoplasmic Dyneins|Biological Transport|Models, Molecular 33 HOOK3 29416113 Nat. Struct. Mol. Biol. 2018 PMC5969528 10.1038/s41594-018-0027-7 0 26 0 276 Mice|Animals|*Dynactin Complex|*Electron Microscope Tomography|Microtubules|Microtubule-Associated Proteins|Cytoplasmic Dyneins|Cytoskeleton|*Cell Movement|Axonemal Dyneins 33 HORMAD1 30461527 Epidemiology 2018 10.1097/EDE.0000000000000946 0 0 0 60 *Cohort Studies|Denmark|*Tonsillectomy|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn Disease|Odds Ratio|Risk Factors|Registries|Family Members 53 HORMAD1 30333500 Sci Rep 2018 PMC6192992 10.1038/s41598-018-33601-w 6 7 0 60 Male|*Recombinational DNA Repair|DNA Copy Number Variations|*Testis|*Lung Adenocarcinomas|*DNA Repair|DNA End-Joining Repair|Homologous Recombination|DNA Breaks, Double-Stranded|TP53BP1 protein, human|Tumor Suppressor p53-Binding Protein 1|Cell Cycle Proteins|Ionizing Radiation|Nuclear Proteins|DNA-Binding Proteins|DNA Damage|Histones|Lung Neoplasms 53 HORMAD1 30270110 Mol. Cell 2018 PMC6426715 10.1016/j.molcel.2018.08.031 10 2 0 60 Mice|Animals|*B-DNA|Synapsis, Chromosomal|Meiosis|DNA Breaks, Double-Stranded|*Oocyte|DNA Repair|DNA Damage|Recombination, Genetic|Cell Cycle Proteins|DNA-Binding Proteins|Chromosomes|*Quality Control 53 HORMAD1 30185546 Cancer Res. 2018 PMC6440700 10.1158/0008-5472.CAN-18-1377 10 1 0 60 Humans|Male|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Prognosis|*Lung Adenocarcinoma|Adenocarcinoma|*Genotoxic Stress|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Antineoplastic Agents|Cell Cycle Proteins|Oxidative Stress|HORMAD1 protein, human 53 HORMAD1 30046392 Oncotarget 2018 PMC6059019 10.18632/oncotarget.25728 5 2 0 60 Humans|rucaparib|*Indoles|Poly(ADP-ribose) Polymerase Inhibitors|Drug Resistance, Neoplasm|Cell Line, Tumor|Homologous Recombination|Gene Expression Profiling|DNA Methylation|Epigenesis, Genetic|HORMAD1 protein, human|Cell Cycle Proteins 53 HORMAD1 29414051 DNA Repair (Amst.) 2018 10.1016/j.dnarep.2018.01.007 8 0 0 60 Male|Mice|Animals|*DNA Breaks, Double-Stranded|Meiosis|*Synapsis, Chromosomal|meiotic recombination protein SPO11|*Endodeoxyribonucleases|Spermatocytes|Cell Cycle Proteins|Chromosomes|DNA 53 HOXA6 29899328 Cell Death Dis 2018 PMC5999602 10.1038/s41419-018-0725-4 4 28 0 56 Humans|Mice|Animals|*RNA, Long Noncoding|*A549 Cells|Cell Proliferation|Lung Adenocarcinoma|Upregulation|Gene Expression Regulation, Neoplastic|Lung Neoplasms|Cell Movement|Cell Line, Tumor|shRNA|Apoptosis|Mice, Nude|Xenograft Model Antitumor Assays|Lung|Acetylation 36 HOXA6 29620285 Int. 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Oncol. 2018 10.3892/ijo.2018.4352 3 11 0 56 Humans|Adult|Caco-2 Cells|*Colorectal Cancer|*Apoptosis|Cell Proliferation|CDH1 protein, human|N-Cadherin|Neoplasm Invasiveness|Signal Transduction|Epithelial-Mesenchymal Transition|Cell Movement|Gene Expression Regulation, Neoplastic|CASP3 protein, human|Caspase 3|Proto-Oncogene Proteins c-akt|Downregulation|Cell Line, Tumor|Upregulation|*Colonic Neoplasms 36 HoxC10 30429891 Theranostics 2018 PMC6217061 10.7150/thno.27310 11 54 0 154 Humans|*Up-Regulation|*Neovascularization, Pathologic|*Glioma|Vascular Endothelial Growth Factor A|Angiogenesis Inhibitors|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Cell Proliferation|Xenograft Model Antitumor Assays|Human Umbilical Vein Endothelial Cells|Cell Movement|VEGFA protein, human|HOXC10 protein, human|Homeodomain Proteins|PRMT5 protein, human|Protein-Arginine N-Methyltransferases 78 HoxC10 30353595 Stem Cells 2018 10.1002/stem.2925 1 0 0 154 Humans|Mice|Animals|*Osteogenesis|*Mesenchymal Stem Cells|Cell Differentiation|Osteoblasts|lncRNA|Stem Cells|Cells, Cultured|Multiple Myeloma|HOXC10 protein, human|Homeodomain Proteins 78 HoxC10 30343692 Biochim Biophys Acta Gene Regul Mech 2018 10.1016/j.bbagrm.2018.09.004 1 0 0 154 Pregnancy|Female|Humans|*Genes, Homeobox|*G-Quadruplexes|*Promoter Regions, Genetic|Circular Dichroism|Base Sequence|Nucleic Acid Conformation|Electrophoretic Mobility Shift Assay|Gene Expression|Gene Expression Regulation, Neoplastic|HOXC10 protein, human|Homeodomain Proteins 78 HoxC10 30284400 Physiol Rep 2018 PMC6170879 10.14814/phy2.13880 1 0 0 154 Rats|Animals|Adipose Tissue, White|Leptin|Adiponectin|mRNA|Body Weight|Physical Conditioning, Animal|Upregulation|DNA-Binding Proteins|Downregulation|Genes, Developmental|Bmpr1a protein, rat|Bone Morphogenetic Protein Receptors, Type I|Gpc4 protein, rat|Glypicans 78 hoxc11 29435418 FEBS Open Bio 2018 PMC5794471 10.1002/2211-5463.12365 4 1 0 92 *miRNA|Gene Expression Profiling|Quantitative Real Time Polymerase Chain Reaction|Gene Expression|*Stomach Neoplasms|*Adenocarcinoma|Stomach 57 hoxd11 30524706 Transl Neurodegener 2018 PMC6276193 10.1186/s40035-018-0135-7 3 1 0 136 *Amyotrophic Lateral Sclerosis|*Neurogenesis|Peptides 126 hoxd11 32532315 Transl Neurodegener 2018 10.1186/s40035-018-0135-7 0 0 0 136 *Amyotrophic Lateral Sclerosis|*Neurogenesis|Peptides 126 hoxd11 30417685 Asian Cardiovasc Thorac Ann 2018 10.1177/0218492318813443 0 2 0 136 *Lung Cancer|Carcinoma, Non-Small-Cell Lung|DNA Methylation|Promoter Regions, Genetic|Biomarkers, Tumor|Tumor Suppressor Proteins|Cadherins|Smoking|Risk Assessment 126 hoxd11 30223853 BMC Biol. 2018 PMC6142630 10.1186/s12915-018-0570-z 3 0 0 136 Animals|Hox Genes|Homeodomain Proteins|Extremities|Gene Expression Regulation, Developmental|Transcription Factors|Forelimb|Hindlimb|Gene Expression 126 hoxd11 29377931 PLoS Genet. 2018 PMC5805373 10.1371/journal.pgen.1007181 7 23 0 136 Mice|Animals|*Nephron|Transcription Factors|Homeodomain Proteins|Organogenesis|*Gene Expression Regulation|Cell Differentiation|Stem Cells|WNT4 protein, human|Wnt4 Protein|Kidney|Mice, Transgenic|Transcriptional Networks|PAX2 Transcription Factor|*Mammals|Sall1 protein, mouse 126 Hoxd9 30247807 J. 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Med. 2018 PMC6237588 10.1111/jcmm.13863 20 0 0 109 Humans|*Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|Neoplasm Recurrence, Local|Nomogram|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Kaplan-Meier Estimate|Liver|Receiver Operating Characteristic|Genes, cdc|Cohort Studies 97 Hrk 30322870 Blood 2018 PMC6318426 10.1182/blood-2018-08-872465 9 0 0 257 *Phosphatidylinositol 3-Kinases|*Phosphoinositide 3 Kinase|BCL2 protein, human|*Proto-Oncogene Proteins c-bcl-2|*Lymphoma, Large B-Cell, Diffuse|venetoclax|Bridged Bicyclo Compounds, Heterocyclic|Sulfonamides|copanlisib|Pyrimidines|Myeloid Cell Leukemia Sequence 1 Protein|Apoptosis|Antineoplastic Agents|Phosphoinositide-3 Kinase Inhibitors|Xenograft Model Antitumor Assays|Cell Line, Tumor|Quinazolines|Cell Proliferation 202 Hrk 30084216 ChemMedChem 2018 10.1002/cmdc.201800321 1 0 0 257 *Proteins, BCL2|Bax protein (53-86)|*Proto-Oncogene Proteins|Anti-Apoptotic Proteins|*Apoptosis|*Peptide Fragments|bcl-X Protein|bcl-2 Homologous Antagonist-Killer Protein|Protein Binding|Amino Acid Sequence|Protein Interaction Domains and Motifs|Molecular Dynamics Simulation|Membrane Proteins|Signal Transduction 202 Hrk 30076411 Oncogene 2018 PMC6596308 10.1038/s41388-018-0436-4 5 3 0 257 Humans|Mice|Animals|PIK3CA protein, human|*Class I Phosphatidylinositol 3-Kinases|Fulvestrant|Receptors, Estrogen|Estrogens|Phosphoinositide-3 Kinase Inhibitors|Protein Kinase Inhibitors|Signal Transduction|Antineoplastic Agents|Phosphatidylinositol 3-Kinases|MCF-7 Cells|TOR Serine-Threonine Kinases|Drug Resistance, Neoplasm|Xenograft Model Antitumor Assays|Estradiol|Cell Line, Tumor 202 Hrk 29988340 Front Microbiol 2018 PMC6023965 10.3389/fmicb.2018.01250 11 0 0 257 202 Hrk 29440992 Front Cell Neurosci 2018 PMC5797550 10.3389/fncel.2018.00015 0 4 0 257 Mice|Animals|*Superoxide Dismutase-1|*Upregulation|*Astrocytes|Amyotrophic Lateral Sclerosis|Motor Neurons|Superoxide Dismutase|Spinal Cord|Mice, Transgenic|*Central Nervous System|*Transcriptional Activation|Disease Models, Animal|Cell Death 202 Hrk 29416632 Oncotarget 2018 PMC5787485 10.18632/oncotarget.23070 3 37 0 257 Male|Humans|*Histone Deacetylase Inhibitors|*G2 Cell Cycle Arrest|*Apoptosis|Cyclin-Dependent Kinase Inhibitor p21|Cell Proliferation|Cyclin-Dependent Kinases|CDC2 Protein Kinase|Cyclins|Cell Cycle Proteins|*Prostate Cancer 202 Hrk 29408822 Cell. Physiol. Biochem. 2018 10.1159/000487159 1 2 0 257 *Gene Editing|*CRISPR-Cas Systems|*CRISPR|*Signal Transduction|G-Protein-Coupled Receptors|Genetic Engineering 202 HSPB3 29969581 J. Mol. Biol. 2018 PMC6119766 10.1016/j.jmb.2018.06.047 9 0 0 1045 Humans|HSP20 Heat-Shock Proteins|alpha-Crystallin B Chain|HSP27 Heat-Shock Proteins|Protein Structure, Quaternary|Amino Acid Sequence|Heat-Shock Proteins, Small|Protein Binding|Heat-Shock Proteins|Sequence Alignment|Models, Molecular|HSPB2 protein, human 48 HSPB3 29341343 J. Peripher. Nerv. Syst. 2018 10.1111/jns.12249 4 0 0 1045 Humans|*Charcot-Marie-Tooth Disease|*Mutation|HSPB1 protein, human|Heat Shock Protein 27|Heat Shock Protein|*Heat Shock|*Axons|Pedigree|small protein B|*RNA-Binding Proteins|Sequencing, Next-Generation 48 HSPB6 30520377 Curr. HIV Res. 2018 PMC6416460 10.2174/1570162X17666181206111859 1 5 0 293 Humans|*HIV-1|*Cell-Penetrating Peptides|*Eukaryotic Cells|nef protein, Human immunodeficiency virus 1|nef Gene Products, Human Immunodeficiency Virus|HIV Vaccines|Transfection|HEK293 Cells|*HIV Seropositivity|Adjuvants, Immunologic|nef protein, Human immunodeficiency virus 2 174 HSPB6 30511325 Cell. Mol. Neurobiol. 2018 10.1007/s10571-018-0637-y 0 12 0 293 Humans|Rats|Animals|*Protein Kinase A|*Kainic Acid|*Cyclic AMP|*Epileptic Seizure|*Epilepsy|Hippocampus|Phosphorylation|Neurons|Signal Transduction|Apoptosis|*Heat Shock|TYRP1 protein, human|*Membrane Glycoproteins|HSPB6 protein, human|HSP20 Heat-Shock Proteins 174 HSPB6 30378628 Food Funct 2018 10.1039/c8fo01604f 0 0 0 293 Mice|Animals|*Wolfiporia|Tandem Mass Spectrometry|*Inflammatory Bowel Disease|Trinitrobenzenesulfonic Acid|Colitis|Colon|Anti-Inflammatory Agents|*Polysaccharides|Sulfasalazine|Cytokines|Peroxidase|Glutathione|Disease Models, Animal 174 HSPB6 30346063 Neuropathol. Appl. Neurobiol. 2018 10.1111/nan.12525 7 0 0 293 *Amyotrophic Lateral Sclerosis|*Astrocytes|Neurodegenerative Diseases|Motor Neurons|*Microglia|Spinal Cord|*Central Nervous System|DNA-Binding Proteins|Cells, Glial|*Heat-Shock Proteins, Small|Upregulation 174 HSPB6 30317011 Meat Sci. 2018 10.1016/j.meatsci.2018.08.016 3 0 0 293 Cattle|Animals|*Proteomics|*Meat|Muscle Proteins|Red Meat|Muscle, Skeletal|*Oxidation-Reduction|Heat Shock Proteins|Myosin|HSPB1 protein, human|HSP27 Heat-Shock Proteins|Oxidative Stress 174 HSPB6 30305007 Reprod Sci 2018 10.1177/1933719118802057 1 2 0 293 Pregnancy|Humans|Female|*Trophoblasts|*Pre-Eclampsia|*Proto-Oncogene Proteins c-akt|*Heat Shock Protein|Placenta|Cell Movement|Apoptosis|Signal Transduction|Down-Regulation|Cell Proliferation|Phosphorylation|Uterus|Cell Line 174 HSPB6 30286088 PLoS ONE 2018 PMC6171826 10.1371/journal.pone.0203155 0 14 0 293 *DNA Methylation|*Gene Expression Profiling|CpG Islands|*Lung Cancer|Oligonucleotide Array Sequence Analysis|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|China 174 HSPB6 30235356 PLoS ONE 2018 PMC6147558 10.1371/journal.pone.0204318 1 0 0 293 Humans|*Skin|Wound Healing|Rejuvenation|Cosmetic Techniques|Cicatrix|Needles|Models, Biological|Standardization|Extracellular Matrix 174 HTATSF1 30567737 J. Biol. Chem. 2018 PMC6393619 10.1074/jbc.RA118.006764 6 3 0 139 *Spliceosomes|*RNA Precursors|*Transcription Factor, SF-1|Ribonucleoprotein, U2 Small Nuclear|*RNA Splicing|U2AF Splicing Factor|RNA Splicing Factors|RNA-Binding Proteins|Ribonucleoproteins|Nuclear Proteins|Phosphoproteins|Protein Binding|Binding Sites|Protein Interaction Domains and Motifs|Amino Acid Sequence|Transcription Factors 26 HTATSF1 29625069 Cell Stem Cell 2018 10.1016/j.stem.2018.03.002 7 0 0 139 Animals|*mRNA|*Pluripotent Stem Cell|*Cell Differentiation|Embryonic Stem Cell|Epiblast|Nanog Homeobox Protein|Homeodomain Proteins|Cell Line|Cells, Cultured|RNA, Ribosomal|*Gene Expression 26 HTATSF1 29625061 Cell Stem Cell 2018 10.1016/j.stem.2018.03.019 0 0 0 139 *Subunit, Ribosomal|Ribosomes|Ribosomal Protein|Protein Biosynthesis|*Cell Differentiation|RNA, Ribosomal|*Stem Cell|RNA, Messenger|Escherichia coli|Models, Molecular 26 HTRA3 30415742 Placenta 2018 10.1016/j.placenta.2018.09.009 1 0 0 62 Pregnancy|Humans|Female|*Pre-Eclampsia|podocalyxin|*Sialoglycoproteins|Placenta Growth Factor|*Early Diagnosis|Gestational Age|Case-Control Studies|Biomarkers|HTRA3 protein, human|Serine Endopeptidases 77 HTRA3 30198900 Acta Crystallogr D Struct Biol 2018 10.1107/S205979831800952X 0 0 0 62 *Mycobacterium tuberculosis|*Hot Temperature|*Temperature|Serine Endopeptidases|PDZ Domain|Amino Acid Sequence|High-Temperature Requirement A Serine Peptidase 1|High-Temperature Requirement A Serine Peptidase 2|Crystallography, X-Ray|Structure-Activity Relationship|Serine Protease|Escherichia coli|Models, Molecular|Mitochondrial Proteins 77 HTRA3 30148508 Acta Biochim. Pol. 2018 10.18388/abp.2018_2623 0 0 0 62 Humans|Child|*Proteases|*Cutaneous Mastocytosis|Serine Endopeptidases|High-Temperature Requirement A Serine Peptidase 1|High-Temperature Requirement A Serine Peptidase 2|Mast Cells|Western Blotting|Apoptosis|HtrA1 protein, human|HTRA3 protein, human 77 HTRA3 30139517 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.08.070 0 2 0 62 Female|Humans|*Endometrial Hyperplasia|Endometrial Cancer|HTRA3 protein, human|*Serine Endopeptidases|Endometrium|Immunohistochemistry|Precancerous Conditions|*Hypoxia 77 HTRA3 29477555 J Proteomics 2018 10.1016/j.jprot.2018.02.022 4 4 0 62 Humans|Pregnancy|Female|*Cytoskeletal Proteins|Cytoskeleton|Protein Folding|Microtubules|Chaperonin Containing TCP-1|Tubulin|Actin|Isoforms|Proteolysis|Intermediate Filaments|Serine Endopeptidases|HTRA3 protein, human 77 ICA1 30290764 Genet. Sel. Evol. 2018 PMC6173862 10.1186/s12711-018-0405-y 3 1 0 128 Animals|Cattle|*Genome-Wide Association Study|*Quantitative Trait Loci|*Heterosis|*Breeding|Phenotype|Quantitative Trait, Heritable|Single Nucleotide Polymorphisms|Genotype|Birth Weight 106 ICA1 30226591 Int. J. Oncol. 2018 PMC6192717 10.3892/ijo.2018.4542 3 3 0 128 Humans|Male|*Prostate|*Factor B|*Signal Transduction|*Prostate Cancer|*Downregulation|Apoptosis|Cell Proliferation|NF-kappa B|I-kappa B Kinase|Cell Line, Tumor|Protein Kinase C|*Cell Nucleus|Phosphorylation 106 IFIT5 30504123 Cancer Res. 2018 10.1158/0008-5472.CAN-18-2207 10 6 0 80 Humans|Male|Mice|Animals|*Epithelial-Mesenchymal Transition|miRNAs|*Prostate Cancer|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Prognosis|Lung Neoplasms|Neoplasm Proteins|Biomarkers, Tumor|Cell Line, Tumor|Xenograft Model Antitumor Assays|Mice, Nude|Apoptosis|Signal Transduction|Transcription Factors|IFIT5 protein, human|MIRN101 microRNA, human 65 IFITM5 30593885 Eur J Med Genet 2018 PMC6594916 10.1016/j.ejmg.2018.12.011 0 0 0 60 Male|Humans|Female|Adolescent|Osteogenesis imperfecta, type 3|Osteogenesis Imperfecta, Type V|*Osteogenesis Imperfecta|Phenotype|Collagen Type I|Mutation|Craniofacial Abnormalities|Bone|Membrane Proteins|Anodontia|Radiography, Panoramic|Cephalometry 82 IFITM5 30289614 Am. J. Med. Genet. A 2018 PMC6347491 10.1002/ajmg.a.40383 0 0 0 60 Humans|Female|Adolescent|Osteogenesis Imperfecta|*Mutation|Collagen Type I|*Bone|Phenotype|Membrane Proteins|Amino Acid Sequence|Craniofacial Abnormalities|Radiography|IFITM5 protein, human 82 IFITM5 30039845 Ann. Hum. Genet. 2018 10.1111/ahg.12275 0 1 0 60 Male|Humans|Osteogenesis Imperfecta, Type V|*Osteogenesis Imperfecta|*Mutation|Phenotype|Heterozygote|Genotype|Membrane Proteins|Genotype-Phenotype Correlation|Bone and Bones|Radiography|IFITM5 protein, human 82 IFITM5 29807018 Clin. Chim. Acta 2018 10.1016/j.cca.2018.05.048 0 4 0 60 Humans|*Osteogenesis Imperfecta|*Genotype-Phenotype Correlation|Mutation|Collagen Type I|Phenotype|Genotype|High-Throughput Nucleotide Sequencing|Malaysia 82 IFITM5 29499418 Bone 2018 10.1016/j.bone.2018.02.029 5 0 0 60 Humans|*Osteogenesis Imperfecta|*Genotype-Phenotype Correlation|Heterozygote|*Asian Continental Ancestry Group|Phenotype|Mutation|Genotype|Sequencing, Next-Generation|Whole Exome Sequencing|Collagen Type I|Tacrolimus Binding Proteins|*Cohort Studies|FKBP10 protein, human 82 IFITM5 29459627 Sci Rep 2018 PMC5818530 10.1038/s41598-018-21601-9 0 41 0 60 Humans|Female|Mice|Animals|*Genistein|*Cell Differentiation|Osteoblast|*Cell Line|Osteogenesis|Bone Mineralization|Phyto-Estrogen|3T3 Cells|Estrogens|Signal Transduction|Up-Regulation|*Bone|Downregulation|Intercellular Signaling Peptides and Proteins 82 IFRD1 30463235 Genes (Basel) 2018 PMC6267452 10.3390/genes9110560 3 0 0 110 Animals|*Newcastle disease virus|Disease, Newcastle|Poultry Diseases|Chickens|Poultry|Antibodies, Viral|Stress, Heat 74 IFRD1 30329049 Inflamm. Bowel Dis. 2018 10.1093/ibd/izy332 0 0 0 110 Humans|Mice|Animals|*Appendectomy|*Appendicitis|*Colitis|Colitis, Ulcerative|Appendix|Inflammatory Bowel Diseases|CCL20 protein, human|Chemokine CCL20|Crohn's Disease|interferon regulatory factor-4|Interferon Regulatory Factors|Oligonucleotide Array Sequence Analysis|Colon|Mice, Inbred BALB C|Th17 Cells|interferon regulatory factor-8|Gene Expression Profiling|Disease Models, Animal 74 IFRD1 29634759 PLoS ONE 2018 PMC5892948 10.1371/journal.pone.0193790 4 42 0 110 *EIF-2|*Phosphorylation|*Ribosome|Protein Biosynthesis|Open Reading Frames|RNA, Messenger|Gene Expression Regulation|Base Sequence|Stress, Physiological|DNA-Binding Proteins 74 IFRD1 29362493 J. Hum. Genet. 2018 10.1038/s10038-017-0394-7 2 0 0 110 *Spastic Paraplegia, Hereditary|*Interferon|*Cerebellar Ataxia|*Ataxia|Sensorimotor neuropathy with ataxia, autosomal dominant|Spinocerebellar Degenerations|Spinocerebellar Ataxias|*Peripheral Neuropathy|Pedigree|Mutation|Phenotype|Mutation, Missense|*Antiviral Agents|Sequencing, Next-Generation 74 IGIP 30319728 J Clin Aesthet Dermatol 2018 PMC6169597 1 0 0 16 29 IGLL5 29921943 Sci Rep 2018 PMC6008462 10.1038/s41598-018-27627-3 1 1 0 24 Humans|*Transcriptome|*Gingiva|Periodontium|*Gene Expression Profiling|*Microarray Analysis|Chronic Periodontitis|Sequencing, RNA|Immunohistochemistry|Real-Time Polymerase Chain Reaction 21 IGLL5 29563506 Blood Cancer J 2018 PMC5862875 10.1038/s41408-018-0062-y 5 0 0 24 *Translocation, Genetic|*Multiple Myeloma|*Point Mutation|DNA Copy Number Variations|Mutation|High-Throughput Nucleotide Sequencing|Aneuploidy 21 IGSF11 30220083 Immunology 2018 PMC6283650 10.1111/imm.13001 18 3 0 18 Humans|*T Cells|Lymphocyte Activation|B7 Antigens|Immunotherapy|Cytokines|*Ligands|Cancers|Antibodies, Monoclonal|Signal Transduction|Cell Proliferation 27 IGSF11 30176341 Neurosci. Lett. 2018 10.1016/j.neulet.2018.08.049 1 3 0 18 Mice|Animals|Male|*Cell Adhesion|*Cell Adhesion Molecules|*Cell Differentiation|Neurons|Cerebellum|*Cytoplasmic Granules|Cell Movement|Cells, Cultured 27 IGSF3 29991755 Cell Death Dis 2018 PMC6039476 10.1038/s41419-018-0813-5 9 4 0 44 Humans|Child|*RNA, Long Noncoding|*miRNAs|*mRNA|*Osteosarcoma|Gene Regulatory Networks|*Sequencing, RNA|Gene Expression Regulation, Neoplastic|*Tumorigenesis|*Cell Transformation, Neoplastic|Gene Ontology|Biomarkers, Tumor|Computational Biology|Transcriptome|*Whole Exome Sequencing|*Lung Neoplasms|Kaplan-Meier Estimate 20 IGSF3 29510755 BMC Med Genomics 2018 PMC5839022 10.1186/s12920-018-0338-x 1 9 0 44 Humans|Child|*Whole Exome Sequencing|Genome-Wide Association Study|Exome|Pedigree|Genetic Predisposition to Disease|Mutations|*Sarcoidosis 20 ILDR1 29849566 Neural Plast. 2018 PMC5926476 10.1155/2018/7272308 2 0 0 64 Humans|*Mutation|Hearing Impairment|Pedigree|Hearing Loss, Sensorineural|Asian Continental Ancestry Group|Sequencing, Next-Generation 35 immp2l 29924831 PLoS ONE 2018 PMC6010250 10.1371/journal.pone.0199178 3 0 0 32 Humans|*Keratoconus|Australia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Cohort Studies|Eye Proteins|Base Sequence|Homeodomain Proteins|*Continental Population Groups|SLC4A11 protein, human|Antiporters|Anion Transport Proteins 57 immp2l 29921919 Cell Res. 2018 PMC6028640 10.1038/s41422-018-0059-x 0 1 0 32 *Mitochondria|*Cellular Senescence|*Endopeptidases 57 immp2l 29882083 Behav. Genet. 2018 PMC6028865 10.1007/s10519-018-9902-6 3 4 0 32 Child|Adult|Humans|*Intellectual Disability|*DNA Copy Number Variations|*Incidence|*Comorbidity|Developmental Disabilities|Chromosome Aberrations|Oligonucleotide Array Sequence Analysis|Chromosomes, Human|Phenotype|Genetic Testing|Cohort Studies 57 immp2l 29808012 Cell Res. 2018 PMC5993829 10.1038/s41422-018-0043-5 5 5 0 32 Animals|*Cell Death|*Signal Transduction|Mitochondria|Mitochondrial Membranes|Apoptosis Inducing Factor|Cellular Senescence|Endopeptidases|Redox|*Biochemical Phenomena 57 immp2l 29788020 Cytogenet. Genome Res. 2018 10.1159/000489001 3 0 0 32 Humans|Male|*Autism Spectrum Disorder|*Genomics|Gene Deletion|Cohort Studies|DNA Copy Number Variations|Sequence Deletion|Case-Control Studies|IMMP2L protein, human|Endopeptidases 57 IMPG1 30300315 Retin Cases Brief Rep 2018 10.1097/ICB.0000000000000824 0 1 0 26 Adult|Humans|*Vitelliform Macular Dystrophy|Bestrophins|Eye Proteins|Visual Acuity|Pedigree|Phenotype|Tomography, Optical Coherence|Mutation 29 IMPG1 29777959 Acta Biomater 2018 10.1016/j.actbio.2018.05.023 5 0 0 26 Humans|Mice|Animals|*Organoids|*Photoreceptor Cells|*Retina|*Pluripotent Stem Cell|*Extracellular Matrix|Photoreceptor Cells, Vertebrate|*Cell Differentiation|Proteoglycans|Eye Proteins|*Organogenesis|BCAN protein, human|Brevican|CD44 protein, human|Hyaluronan Receptors 29 INSL4 30423141 J. Natl. Cancer Inst. 2018 PMC6624166 10.1093/jnci/djy166 0 1 0 17 *Lung Cancer|Non-Small-Cell Lung Carcinomas|*Signal Transduction|Protein-Serine-Threonine Kinases|Cell Line, Tumor|AMP-Activated Protein Kinases|Mutation|Gene Expression Regulation, Neoplastic|Phosphorylation|Cell Proliferation 45 INSL4 29623915 Neural Regen Res 2018 PMC5900493 10.4103/1673-5374.228713 0 2 0 17 *Relaxin|*Neuroprotection|Evolution, Molecular|Phylogeny|Insulin|Protein Binding|Signal Transduction 45 insl6 30229969 Anim. Genet. 2018 10.1111/age.12722 3 0 0 28 Animals|*Goat|Pakistan|Genetics, Population|Breeding|Inbreeding|Gene Frequency|Linkage Disequilibrium|Selection, Genetic|Genetic Variation|Genotype|Phenotype|Heterozygote|Population Density|Polymorphism, Single Nucleotide|Genetic Structures 40 insl6 29887522 J Am Heart Assoc 2018 PMC6220528 10.1161/JAHA.117.008441 2 1 0 28 Mice|Animals|*Ventricular Remodeling|*Relaxin|*Heart Failure|Ventricular Function, Left|Hypertrophy, Left Ventricular|Ventricular Dysfunction, Left|Myocardium|*Heart|Mice, Knockout|Fibrosis|Mice, Inbred C57BL|Signal Transduction|Arterial Pressure|Disease Models, Animal|Aorta|Insulins|Insl6 protein, mouse|Intracellular Signaling Peptides and Proteins 40 insl6 29623915 Neural Regen Res 2018 PMC5900493 10.4103/1673-5374.228713 0 2 0 28 *Relaxin|*Neuroprotection|Evolution, Molecular|Phylogeny|Insulin|Protein Binding|Signal Transduction 40 INSRR 30386171 Curr. Genomics 2018 PMC6194433 10.2174/1389202919666171229145156 10 3 0 284 Humans|Animals|Child|*Alzheimer Disease|*Epigenetics|Maternal Deprivation|Glycogen Synthase Kinase 3 beta|Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|*Epigenesis, Genetic|Tauopathy|Brain|Mitogen-Activated Protein Kinases|Mitogen-Activated Protein Kinase 8|Stress, Life 86 INSRR 29992036 J Anim Sci Technol 2018 PMC5994657 10.1186/s40781-018-0171-y 0 7 0 284 Female|Sheep|Animals|*Protein Interaction Maps|*Granulosa Cells|*Ovarian Follicles|*Transcriptome Profiling|Luteal Phase|*Sheep, Domestic|Proteins 86 INVS 30576805 Gene 2018 10.1016/j.gene.2018.12.016 1 0 0 384 *Citrus maxima|*Fruit|*Sugar|*Carbohydrate Metabolism|*Transcriptome Analysis|sucrose synthase|Glucosyltransferases|Gene Expression Regulation, Plant|Transcriptome|Genes, Plant|Sucrose|Invertase|Plant Proteins|China|Malaysia 684 INVS 30368940 Pediatr Allergy Immunol 2018 10.1111/pai.12998 4 0 0 384 Infant, Newborn|Humans|Animals|Child|*Mating Factor|*Breast Milk|*Allergy, Food 684 INVS 30154318 Int J Environ Res Public Health 2018 PMC6163671 10.3390/ijerph15091856 7 0 0 384 *Temperature|*Air Pollution|Particulate Matter|Air Pollutants|Nitrogen Dioxide|Ozone|Sulfur Dioxide|Weather|Seasons|Cities|Cardiovascular Diseases|Age Factors|Sex Factors|Europe|Time Factors 684 INVS 30082245 Prog. Urol. 2018 10.1016/j.purol.2018.06.010 0 0 0 384 Humans|*Urologic Surgical Procedures|Surgical Site Infections|Antibiotic Prophylaxis|Urinary Tract Infections|Urology|*Communicable Diseases|Risk Factors 684 INVS 30001383 PLoS ONE 2018 PMC6042759 10.1371/journal.pone.0200619 3 19 0 384 Dogs|Animals|*Mouth Neoplasms|*Proteomics|*Tandem Mass Spectrometry|Chromatography, Liquid|Carcinoma, Squamous Cell|*Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Proteome|Fingerprints, Peptide|Biomarkers, Tumor|Neoplasm Proteins|Peptides 684 INVS 29948658 Plant Mol. Biol. 2018 10.1007/s11103-018-0746-5 3 0 0 384 *beta-Fructofuranosidase|*Zea mays|Gene Expression Regulation, Plant|Plant Leaves|Plant Proteins|Plant Roots|Cell Wall|Gene Expression Regulation, Enzymologic|Starch|Vacuoles|Sucrose|Phylogeny|Biomass 684 INVS 29927960 PLoS ONE 2018 PMC6013225 10.1371/journal.pone.0198719 0 0 0 384 Humans|*Occupational Exposure|*Mental Disorders|Workplace|Occupational Diseases|*Problem Behavior|Stress, Psychological|Surveys and Questionnaires|Health Personnel|*Thesaurus 684 IPO7 30207007 J. Mol. Recognit. 2018 10.1002/jmr.2763 1 3 0 322 Humans|*RNA, Long Noncoding|*Human Embryonic Stem Cells|Gene Regulatory Networks|Sequence Analysis, RNA|Gene Expression Profiling|RNA, Messenger|MicroRNAs|Transcriptome|Computational Biology|Genes, cdc|Cell Cycle 55 IPO7 30195762 Mol Ther Nucleic Acids 2018 PMC6023947 10.1016/j.omtn.2018.05.009 28 0 0 322 Humans|*RNA, Long Noncoding|*Exosomes|*Downregulation|*Upregulation|*Colorectal Cancer|RNA, Micro|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Cell Movement|Cell Proliferation|*Transcriptional Activation|RNA Silencing|Cell Line, Tumor|mRNA|Apoptosis|*Biopsies|KIF2A protein, human|Kinesin 55 IPO7 30045750 J. Exp. Clin. Cancer Res. 2018 PMC6060558 10.1186/s13046-018-0843-y 5 19 0 322 Humans|*Curcumin|*Proteomics|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Tyrosine Kinase, Bcr-Abl|Gleevec|K562 Cells|Benzamides|Piperazines|Pyrimidines|Apoptosis|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Gene Expression Regulation, Leukemic|*Hypoxia-Inducible Factor 1|Cell Line, Tumor|MicroRNAs|Cell Proliferation|Set2 protein, human 55 IPO7 29765550 Oncotarget 2018 PMC5940416 10.18632/oncotarget.25117 2 32 0 322 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|MAPK1 protein, human|MAP Kinase 2|*Signal Transduction|Elk-1 Transcription Factor|Phosphorylation|Transcription Factors|Mitogen-Activated Protein Kinases|DNA-Binding Proteins|ERK1-2 Pathway|Carrier Proteins|Cell Nucleus|Cell Line, Tumor|MTBP protein, human 55 IRG1 30522781 Eur. J. Cell Biol. 2018 10.1016/j.ejcb.2018.11.004 3 6 0 3025 Animals|Sheep|TLR4 protein, human|*Toll-Like Receptor 4|*Salmonella typhimurium|*Lipopolysaccharides|*Macrophages|Myeloid Differentiation Factor 88|TLR3 protein, human|Toll-Like Receptor 3|IRAK4 protein, human|Interleukin-1 Receptor-Associated Kinases|Signal Transduction|Adaptor Proteins, Vesicular Transport|Cytokines|Immunity, Innate 90 IRG1 30471346 Neurobiol Learn Mem 2018 PMC6547825 10.1016/j.nlm.2018.11.008 7 0 0 3025 Male|Mice|Animals|*Diet, High-Fat|HCRT protein, human|*Orexins|*Cognitive Decline|Hippocampus|Memory|Memory Disorders|Obesity|Microglia|Mice, Inbred C57BL|Transgenic Mouse|Hypothalamus|Encephalitis|Avoidance Learning|Cognitive Function|Irg1 protein, mouse|Hydro-Lyases 90 IRGC 29892844 Genes Genomics 2018 10.1007/s13258-017-0640-6 3 0 0 17 *Quantitative Trait Loci|*Oryza|*Edible Grain|Chromosome Mapping|Crosses, Genetic|Genes, Plant|Chromosomes, Plant|Seeds|Phenotype|Plant Leaves|*Food Hypersensitivity|Genetic Association Studies 32 IRGC 29663580 Acad Emerg Med 2018 10.1111/acem.13432 2 0 0 17 Humans|*Renal Colic|*Point-of-Care Systems|*Consensus|*Ultrasonography|*Hydronephrosis|*Emergency Service, Hospital|*Radiologists|Tomography, X-Ray Computed|Sensitivity and Specificity|Prospective Studies 32 IRGC 29481704 Risk Anal. 2018 10.1111/risa.12977 0 0 0 17 *Natural Gas|Retrospective Studies|*Risk Assessment|Risk Management|Environmental Exposure|*Governments|Uncertainty|Australia|Communication 32 IRX3 30522931 EBioMedicine 2018 PMC6354701 10.1016/j.ebiom.2018.11.048 7 2 0 167 *Obesity|*Hypothalamus|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Diet, High-Fat|Body Weight|Energy Expenditure|Obese Protein|Homeodomain Proteins|Transcription Factors 185 IRX3 30522793 J. Diabetes Complicat. 2018 10.1016/j.jdiacomp.2018.11.002 2 0 0 167 Pregnancy|Female|Mice|Animals|*Diabetes, Gestational|*DNA Methylation|Epigenesis, Genetic|CpG Islands|Glucose Intolerance|Fetal Blood|Obesity|Insulin Resistance|Prenatal Exposure Delayed Effects|Hyperglycemia|*Pancreas|GTP-Binding Protein alpha Subunits, Gs|DNA 185 IRX4 30081002 Gen. Comp. Endocrinol. 2018 10.1016/j.ygcen.2018.08.007 2 0 0 60 Male|Female|Animals|*Sex Differentiation|Gonads|*Fishes|*Transcriptome Analysis|Ovary|CYP19A1 protein, human|Aromatase|Transcriptome|Testis|Germ Cells|Sex Development|Estrogens|Cell Differentiation 63 IRX4 30031117 Cancer Lett. 2018 10.1016/j.canlet.2018.07.020 5 2 0 60 Humans|Mice|Animals|*Carcinoma, Non-Small-Cell Lung|*Transcription Factors|*Lung Neoplasms|Mice, Nude|A549 Cells|Lung Adenocarcinoma|Gene Expression Regulation, Neoplastic|Short Hairpin RNA|RNA Interference|Tumor Burden|Cell Proliferation|Cell Line, Tumor|CCND1 protein, human|Cyclin D1|CBFA2T3 protein, human|Tumor Suppressor Proteins|Homeodomain Proteins|Xenograft Model Antitumor Assays 63 IRX4 29295941 Plant Physiol. 2018 PMC5841686 10.1104/pp.17.01733 3 3 0 60 *E3 Ligase|cinnamoyl CoA reductase|Rice|*Aldehyde Oxidoreductases|Gene Expression Regulation, Plant|*Cell Wall|Plant Proteins|ATP dependent 26S protease|Proteasome Endopeptidase Complex|Arabidopsis|Plants, Genetically Modified|Genes, Plant|Plant Roots|Ubiquitination 63 ISL2 29623822 Protein Pept. Lett. 2018 10.2174/0929866525666180406142128 0 0 0 74 *Glucose|Diabetes Mellitus, Type 2|*Muscle Fibers, Skeletal|Insulin|Insulin Resistance|*Proteins|Muscle, Skeletal|Signal Transduction|Homeostasis|*Mass Spectrometry|Vitamin D|*Dietary Supplements 55 ISM1 29758043 PLoS ONE 2018 PMC5951578 10.1371/journal.pone.0196872 1 14 0 121 Animals|Humans|*Zebrafish|Hematopoiesis|Zebrafish Proteins|Hematopoietic Stem Cells|Animals, Genetically Modified|Gene Expression Regulation, Developmental|Cells, Cultured|Transcriptome|isthmin protein, zebrafish 26 isx 30118149 Cytometry A 2018 PMC6174940 10.1002/cyto.a.23493 4 0 0 94 *Micronucleus Tests|Flow Cytometry|*Automation|*Cell Nucleus|Mutagens|Cytokinesis|DNA Damage|Microscopy|Image Processing, Computer-Assisted 76 isx 29882710 FASEB J. 2018 PMC6181638 10.1096/fj.201800467R 1 0 0 94 Humans|Mice|Animals|*Carotenoids|Retina|Zeaxanthin|Retinoids|Retinaldehyde|Vision|Light|BCO2 protein, human|Dioxygenases|Bco2 protein, mouse 76 isx 29485473 Shock 2018 PMC6109623 10.1097/SHK.0000000000001133 2 2 0 94 Humans|Mice|Animals|*Human Induced Pluripotent Stem Cells|*Regeneration|Cell Differentiation|Myocytes, Cardiac|*Organogenesis|*Fibrosis|Stem Cell Transplantation|Myocardial Infarction|Signal Transduction|Cells, Cultured|Transcription Factors 76 isx 29403509 Front Plant Sci 2018 PMC5786559 10.3389/fpls.2017.02234 0 27 0 94 ANP1 kinase|*Arabidopsis|*Protein Kinases|*Cell Wall|Arabidopsis Proteins|Gene Expression Regulation, Plant|Seedlings|MAP Kinase Kinase Kinase|Cytokinesis|Plant Roots|Genes, Plant|Pectins 76 isx 29311646 Sci Rep 2018 PMC5758610 10.1038/s41598-017-18324-8 4 2 0 94 Mice|Animals|*Dopaminergic Neurons|*Silica|*Fibroblasts|Cellular Reprogramming|Cell Differentiation|*Nanoparticles|Transcription Factors|Dopamine|Transfection 76 ITIH5 30533020 PLoS ONE 2018 PMC6289462 10.1371/journal.pone.0208709 0 0 0 60 Dogs|Animals|Mice|*Epigenesis, Genetic|trichostatin A|Hydroxamic Acids|DNA Methylation|Histone Deacetylase Inhibitors|Azacytidine|Lymphoma, Large B-Cell, Diffuse|Vorinostat|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Promoter Regions, Genetic|Valproic Acid|*Gene Expression|Dog Diseases|RASAL3 protein, mouse|ras GTPase-Activating Proteins 37 ITIH5 30206710 Med. Oncol. 2018 10.1007/s12032-018-1202-8 2 0 0 60 Humans|*Neoadjuvant Therapy|*Whole Exome Sequencing|Neoplasm Recurrence, Local|*Chemoradiotherapy|Rectal Neoplasms|*Rectum|Prognosis|Antineoplastic Combined Chemotherapy Protocols|Treatment Outcome|Retrospective Studies|Biomarkers, Tumor|Genetic Variation|ITIH5 protein, human|Proteinase Inhibitory Proteins, Secretory 37 ITIH5 29626357 J. Cell. Biochem. 2018 10.1002/jcb.26830 3 5 0 60 Humans|*RNA, Long Noncoding|*Hirschsprung Disease|*Cell Migration|RNA, Micro|Downregulation|Cell Proliferation|Up-Regulation|RNA, Small Interfering|Cell Line, Tumor|Colon|HEK293 Cells|ITIH5 protein, human|Proteinase Inhibitory Proteins, Secretory|MIRN31 microRNA, human 37 ITM2A 30056829 J. Am. Coll. Cardiol. 2018 10.1016/j.jacc.2018.04.085 11 0 0 90 Animals|*RNA, Long Noncoding|Cardiomyocyte|Regeneration|Myocardial Infarction|MicroRNAs|Cell Proliferation|Animals, Newborn|Signal Transduction 47 ITM2A 29913145 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.06.041 5 1 0 90 Mice|Animals|FMOD protein, human|*Fibromodulin|*Cell Differentiation|Myoblasts|T-Type Calcium Channel|Calcium Channels, L-Type|Muscular Diseases|Muscle, Skeletal|Cell Line|Gene Knockdown 47 ITM2A 29746958 Biochim Biophys Acta Gen Subj 2018 10.1016/j.bbagen.2018.05.004 5 0 0 90 *RNA, Micro|*mRNA|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Computational Biology|*Hippocampus|*Physical Exercise 47 ITM2C 30480246 J Alzheimers Dis Rep 2018 PMC6159705 10.3233/ADR-170051 0 3 0 80 Humans|Animals|Mice|Alzheimer Disease|Amyloid beta-Peptides|Amyloid|Amyloid beta-Protein Precursor|Plaque, Amyloid|Brain|Membrane Proteins|Membrane Glycoproteins|Hippocampus|Neurons 27 ITM2C 30079703 Balkan Med J 2018 PMC6335938 10.4274/balkanmedj.2018.0356 0 0 0 80 Humans|*Multiple Myeloma|*Bone Marrow|*Transcriptome Analysis|*Gene Expressions|Flow Cytometry|B Cells 27 ITM2C 30042348 Int J Mol Sci 2018 PMC6121261 10.3390/ijms19082161 1 4 0 80 *Plasma Cells|*Transcriptome|*Cell Surface Proteins|Antibody-Secreting Cells|B-Lymphocytes|Production, Antibody|Humoral Immunity|Multiple Myeloma|Bone Marrow Cells|Cell Differentiation 27 KCNT2 30334255 J. Physiol. (Lond.) 2018 PMC6312452 10.1113/JP276806 4 2 0 55 Pregnancy|Female|Humans|*Oxytocin|*Uterine Muscle|Uterine Contraction|*Muscle, Smooth|Uterus|*Sodium|Membrane Potentials|Potassium Channel|Smooth Muscle Cells 56 KCNT2 30073298 JAMA Ophthalmol 2018 PMC6233836 10.1001/jamaophthalmol.2018.3190 4 4 0 55 Humans|*Genome-Wide Association Study|*Central Serous Chorioretinopathy|*Complement|Complement Factor H|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Fluorescein Angiography|Case-Control Studies|European Continental Ancestry Group|Tomography, Optical Coherence 56 KCNT2 29863912 FASEB J. 2018 PMC6181635 10.1096/fj.201800139R 3 1 0 55 Mitochondria, Heart|Potassium Channels|Myocytes, Cardiac|Potassium Channel Blockers|Membrane Potential, Mitochondrial|Potassium 56 KCNT2 29740868 Ann. Neurol. 2018 10.1002/ana.25248 4 0 0 55 Humans|Female|*Gain of Function Mutation|West Syndrome|Potassium Channel|Focal Seizures|Lennox Gastaut Syndrome|Quinidine|Electroencephalography|Mutation|Nerve Tissue Proteins|Membrane Potentials|KCNT2 protein, human|Potassium Channels, Sodium-Activated 56 KCNT2 29626196 Leukemia 2018 PMC6170391 10.1038/s41375-018-0092-2 3 0 0 55 Child|Humans|*Transcriptome|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Mutation|DNA Methylation|High-Throughput Nucleotide Sequencing|Base Sequence|Diploidy|B-Lymphocytes|Cohort Studies|KCNT2 protein, human|Potassium Channels, Sodium-Activated 56 KCNT2 29478594 Handb Clin Neurol 2018 10.1016/B978-0-444-64076-5.00030-2 6 0 0 55 Humans|*Epilepsy|NAV1.1 Voltage-Gated Sodium Channel|Seizure|Genetic Testing|Mutation|Receptors, GABA-A 56 KCTD12 30157793 BMC Cancer 2018 PMC6114029 10.1186/s12885-018-4765-z 2 12 0 183 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|DNA-Binding Proteins|Transcription Factors|Signal Transduction|Neoplastic Stem Cells|Biomarkers, Tumor 55 KCTD12 29930747 Oncotarget 2018 PMC6007475 10.18632/oncotarget.25469 3 6 0 183 Gastrointestinal Stromal Tumors|Prognosis|Biomarkers, Tumor|Proteins 55 KIAA0196 30210277 Front Neurosci 2018 PMC6119822 10.3389/fnins.2018.00592 4 1 0 71 Humans|*African Americans|*Alzheimer Disease|Genome-Wide Association Study|Genetic Predisposition to Disease|European Continental Ancestry Group|ATP-Binding Cassette Transporters 35 KIAA0196 29907907 Neurol. Sci. 2018 10.1007/s10072-018-3454-7 1 1 0 71 Humans|*Paraparesis, Spastic|Spastic paraplegia 9, autosomal dominant|Spastic Paraplegia, Hereditary|Spastin|Mutation|Adenosine Triphosphatases|Genetic Predisposition to Disease|Membrane Proteins|GTP-Binding Proteins|Pedigree|Sequencing, Whole Exome|Asian Continental Ancestry Group|Motor Neuron Disease, Upper|Bone and Bones|Cataract|Growth Disorders|Turkey|SPAST protein, human 35 KIAA0196 29768361 Medicine (Baltimore) 2018 PMC5976306 10.1097/MD.0000000000010760 1 0 0 71 Humans|Spastic Paraplegia Type 8|*Spastic Paraplegia, Hereditary|*Paraplegia|*Chinese|Pedigree|Mutation|Proteins|KIAA0196 protein, human 35 KLF11 30564273 Front Genet 2018 PMC6288315 10.3389/fgene.2018.00608 3 0 0 368 Animals|Swine|*Transcriptome Analyses|Transcriptome|Meat|Breeding|Phenotype|Adipose Tissue|Lipid Metabolism|*Paraspinal Muscles 136 KLF14 30400002 Endocr. Relat. Cancer 2018 10.1530/ERC-18-0383 2 5 0 13 Humans|Male|Mice|Animals|*Hemeoxygenase 1|Phosphatidylinositol 3-Kinases|*Signal Transduction|Prostatic Neoplasms, Castration-Resistant|Proto-Oncogene Proteins c-akt|Cell Proliferation|Receptors, Androgen|Upregulation|Cell Line, Tumor|Apoptosis|Cell Cycle|3'-(1-butylphosphoryl)adenosine|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|Oxidative Stress|Activation, Transcriptional|KLF14 protein, human|Sp Transcription Factors 86 KLF14 30300865 Forensic Sci Int Genet 2018 10.1016/j.fsigen.2018.09.010 5 0 0 13 *DNA Methylation|*B-DNA|*Saliva|CpG Islands|Forensic Genetics|Genetic Markers|Sequence Analysis, DNA|DNA|Polymerase Chain Reaction 86 KLF14 30254317 Lab. Invest. 2018 10.1038/s41374-018-0134-4 1 0 0 13 Humans|Mice|Animals|*Liver|Autoimmune Hepatitis|Concanavalin A|T-Cells, Regulatory|Mice, Inbred C57BL|Hepatocytes|Cytokines|Antigens, CD|Interleukin 6|Flow Cytometry|KLF14 protein, human|Sp Transcription Factors|Klf14 protein, mouse|Kruppel-Like Transcription Factors 86 KLF14 30248551 Atherosclerosis 2018 PMC6441279 10.1016/j.atherosclerosis.2018.09.018 6 11 0 13 Mice|Humans|Animals|*Coronary Artery Disease|*Transcription Factor|*Signal Transduction|*Inflammation|*Gene Expression Regulation|Atherosclerosis|NF-kappa B|Vascular Cell Adhesion Molecule-1|Kruppel-Like Transcription Factors|Human Umbilical Vein Endothelial Cells|Mice, Inbred C57BL|3'-(1-butylphosphoryl)adenosine|Tumor Necrosis Factor-alpha|Cell Adhesion|Klf14 protein, mouse 86 KLF14 30216442 J. Cell. Physiol. 2018 10.1002/jcp.26779 11 5 0 13 Humans|*Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Hep G2 Cells|Tumorigenesis|Cell Proliferation|Cell Movement|Up-Regulation|Cell Line, Tumor|Apoptosis|Disease Progression|KLF14 protein, human|Sp Transcription Factors|MIRN346 microRNA, human 86 KLF14 30087441 Nat. Genet. 2018 10.1038/s41588-018-0180-2 1 0 0 13 Female|*Diabetes Mellitus, Type 2|*Body Composition|*Adipocyte|*Risk|Interior Design and Furnishings 86 KLF14 30078677 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.07.125 17 7 0 13 Humans|*RNA, Long Noncoding|*Colorectal Cancer|*Upregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|*Disease Progression|Cell Proliferation|Cell Movement|Cell Line, Tumor|*Neoplastic Processes|Apoptosis|*Transcriptional Activation|*Colonic Neoplasms|KLF14 protein, human|Sp Transcription Factors|HAND2 protein, human|Basic Helix-Loop-Helix Transcription Factors|MIRN1275 microRNA, human 86 KLF14 30050001 Genes (Basel) 2018 PMC6115814 10.3390/genes9080374 3 14 0 13 *Diabetes Mellitus, Type 2|Genome-Wide Association Study|Transcription Factor 7-Like 2 Protein|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Genomics 86 KLF16 29953649 J. Cell. Biochem. 2018 10.1002/jcb.27167 3 5 0 93 Humans|*Glioblastoma|*RNA, Long Noncoding|*MicroRNAs|Brain Neoplasms|Cell Proliferation|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|RNA, Small Interfering|Cell Cycle|MIRN185 microRNA, human 26 KLF16 29860460 Invest. Ophthalmol. Vis. Sci. 2018 PMC5983061 10.1167/iovs.17-23319 3 19 0 93 Axons|Optic Nerve Injuries|Nerve Regeneration|Nerve Crush|Retinal Ganglion Cells|Optic Nerve|Central Nervous System|Cell Survival|Gene Expression Regulation|Kruppel-Like Transcription Factors|Cells, Cultured 26 KLF16 29374989 Artif Cells Nanomed Biotechnol 2018 10.1080/21691401.2018.1431654 2 1 0 93 Humans|*Glioma|*Cell Proliferation|Transcription Factors|DNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Mitochondrial Proteins|Cell Line, Tumor|TFAM protein, human 26 KLF8 30528231 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.11.183 3 2 0 370 *RNA, Long Noncoding|*Urinary Bladder Neoplasms|*Factor VIII|*Disease Progression|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Movement|Cell Proliferation|MicroRNAs|*Bladder|*Neoplastic Processes|Oncogenesis|Cell Line, Tumor 102 KLF8 30479372 Sci Rep 2018 PMC6258679 10.1038/s41598-018-35786-6 0 5 0 370 Mice|Animals|*Carcinoma, Hepatocellular|*Factor VIII|*Liver Neoplasms|Phosphatidylinositol 3-Kinases|*Neovascularization, Pathologic|Signal Transduction|Proto-Oncogene Proteins c-akt|Focal Adhesion Kinase|Gene Expression Regulation, Neoplastic|Vascular Endothelial Growth Factor A|Phosphoinositide-3 Kinase Inhibitors|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one|Chromones|Cell Line, Tumor|Angiogenesis Inhibitors|Nude Mouse|Morpholines 102 KLF8 30369477 Yi Chuan 2018 10.16288/j.yczz.18-095 1 4 0 370 Humans|Animals|Transcription Factors|Gene Expression Regulation|Kruppel-Like Transcription Factors|Muscle, Skeletal|Cardiac Muscle|Muscle, Smooth|KLF8 protein, human|Repressor Proteins 102 KLF8 30341009 Mol. Ther. 2018 PMC6318784 10.1016/j.ymthe.2018.09.016 3 0 0 370 Humans|*Adenovirus|Oncolytic Viruses|Oncolytic Virotherapy|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Adenovirus E1A Proteins|RNA, Micro|Virus Replication|Xenograft Model Antitumor Assays|Cell Line, Tumor|ELF4 protein, human|DNA-Binding Proteins|Transcription Factors|KLF8 protein, human|Repressor Proteins|MIRN485 microRNA, human 102 KLF8 30301149 Int J Mol Sci 2018 PMC6213902 10.3390/ijms19103037 0 11 0 370 Mice|Animals|*Goat|Adipogenesis|Adipocyte|*Cell Differentiation|3T3-L1 Cells|CCAAT-Enhancer-Binding Protein-alpha|NR1H3 protein, human|Liver X Receptor-Alpha|CCAAT-Enhancer-Binding Protein-beta|Sterol Regulatory Element Binding Protein 1|PPAR gamma|Lipid Metabolism|Fatty Acid-Binding Proteins|Cells, Cultured|RNA, Messenger 102 KLK10 30589909 PLoS ONE 2018 PMC6307750 10.1371/journal.pone.0209750 4 0 0 169 Humans|Mice|Animals|*Genes, Tumor Suppressor|3' UTR|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|CCND1 protein, human|Cyclin D1|Colorectal Cancer|HCT116 Cells|Downregulation|Forkhead Box Protein M1|Cell Cycle|Oncogenesis|Cell Line, Tumor|mRNA|Apoptosis|Cell Movement|Colonic Neoplasms 148 KLK10 30504243 Mol. Cell Proteomics 2018 PMC6398207 10.1074/mcp.RA118.000757 0 0 0 169 Humans|Female|*HIV Infections|Sex Workers|HIV-1|Cervix Uteri|Vagina|Mucosa|*Mass Screening 148 KLK10 30323977 Am J Cancer Res 2018 PMC6176182 2 1 0 169 Female|Humans|*Kallikrein|*Ovarian Cancer|*Cystadenocarcinoma, Serous|*Prognosis|trypsin-like serine protease|Carcinoma, Ovarian Epithelial|TYRP1 protein, human|*Membrane Glycoproteins|mRNA|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Analysis|Progression-Free Survival|Immunohistochemistry|Cohort Studies|KLK10 protein, human 148 KLK10 30270115 J. Dermatol. Sci. 2018 10.1016/j.jdermsci.2018.09.001 0 2 0 169 *Serine Peptidase Inhibitor Kazal-Type 5|*Keratinocytes|*Epidermis|Netherton Syndrome|Epidermal Cells|Kallikrein|*Toll-Like Receptor|Proteinase Inhibitory Proteins, Secretory|*Signal Transduction|Cells, Cultured|Up-Regulation|Cytokines 148 KLK10 29883315 Biol. Chem. 2018 10.1515/hsz-2017-0338 1 10 0 169 Humans|*Kallikrein|*Neutrophils|*Kinins|Kininogens|Tissue Kallikreins|Inflammation|KLK6 protein, human|KLK13 protein, human|KLK10 protein, human 148 KLK10 29807015 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.05.165 4 4 0 169 Humans|Female|*Uterine Cervical Neoplasms|*Downregulation|3' Untranslated Region|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|*Neoplastic Processes|Cell Line, Tumor|Apoptosis|HeLa Cells|Disease Progression|KLK10 protein, human|Kallikreins 148 KLK10 29707153 Oncotarget 2018 PMC5915161 10.18632/oncotarget.24947 7 7 0 169 *Kallikrein|*Prognosis|*Cancer|Tissue Kallikreins|Gene Expression Regulation, Neoplastic|RNA, Messenger 148 KLK15 29958881 Clin. Biochem. 2018 10.1016/j.clinbiochem.2018.06.017 0 0 0 19 Male|Humans|*Prostate|*Tissue Kallikreins|*Testis|KLK15 protein, human|*Kallikrein|Prostate Cancer|Biomarkers, Tumor|RNA, Messenger 53 KLK15 29928903 Clin. Biochem. 2018 10.1016/j.clinbiochem.2018.06.007 0 0 0 19 Male|Humans|*Tissue Kallikreins|KLK15 protein, human|*Kallikreins|Prostatic Neoplasms|Cell Line, Tumor|RNA, Messenger 53 KLK15 29707153 Oncotarget 2018 PMC5915161 10.18632/oncotarget.24947 7 7 0 19 *Kallikrein|*Prognosis|*Cancer|Tissue Kallikreins|Gene Expression Regulation, Neoplastic|RNA, Messenger 53 KLLN 30482293 Anal. Chim. Acta 2018 10.1016/j.aca.2018.09.032 1 0 0 121 Humans|Female|*Pilot Projects|BRCA2 protein, human|*BRCA2 Protein|BRCA1 protein, human|*BRCA1 Protein|*Genes, BRCA2|*Sequencing, Next-Generation|Genetic Testing|Ovarian Cancers|Germ-Line Mutation|Mutations|Genetic Predisposition to Disease|*PCR|Pedigree|Mutation, Missense|ATAD2 protein, human|ATPases Associated with Diverse Cellular Activities|DNA-Binding Proteins 31 KLLN 30301738 J. Med. Genet. 2018 10.1136/jmedgenet-2018-105471 0 0 0 121 Autosomal Recessive Primary Microcephaly|Microcephaly|Pedigree|Intellectual Disability|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|Genetic Predisposition to Disease|Mutation|*Chromosome Structures 31 KLLN 30245854 Cell Death Discov 2018 PMC6134104 10.1038/s41420-018-0094-x 3 39 0 121 *Phosphorylation|*Acetylation|*Tumor Suppressor Protein p53|*B-DNA|*Apoptosis|Tumor Suppressor Proteins|DNA-Binding Proteins|DNA Damage|Cell Line, Tumor|Promoter Regions, Genetic|DNA Methylation 31 KLLN 29896272 J Cancer 2018 PMC5995936 10.7150/jca.23239 6 10 0 121 31 KLLN 29322795 Neoplasma 2018 10.4149/neo_2018_161122N581 1 1 0 121 Humans|Male|Female|Aged|*Nuclear Protein|*DNA Methylation|In Situ Hybridization, Fluorescence|*Testis|*Carcinoma|SMARCB1 protein, human|SMARCB1 Protein|Maxillary Sinus Neoplasms|*Sinonasal Tract|Oncogene Proteins|Immunohistochemistry|Genes, p16|Genes, cdc|Oncogene Proteins, Fusion|Biomarkers, Tumor|Nasal Cavity|Cytokeratin|Genes, ras 31 KLRC4 30341905 J. Cell. Physiol. 2018 10.1002/jcp.27576 0 0 0 16 Humans|*Immunogenetics|Genome-Wide Association Study|HLA-B51 Antigen|Aminopeptidases|Genetic Predisposition to Disease|Behcet Syndrome|Minor Histocompatibility Antigens|HLA-B Antigens|IL23R protein, human|Receptors, Interleukin|Genotype|IL10 protein, human|Interleukin-10|ERAP1 protein, human 24 KLRC4 30069262 Open Rheumatol J 2018 PMC6040213 10.2174/1874312901812010070 3 5 0 16 *Behcet Syndrome|IL23R protein, human|Receptors, Interleukin|Genetic Susceptibility|STAT4 Transcription Factor|Genome-Wide Association Study|*Regulatory Genes|Alleles|Polymorphism, Single Nucleotide|HLA-B|Genes, MHC Class I 24 KYNU 30267217 Eur Arch Otorhinolaryngol 2018 10.1007/s00405-018-5134-x 0 0 0 204 *Induction Chemotherapy|*Laryngeal Neoplasms|Carcinoma, Squamous Cell|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Squamous Cell Carcinoma of Head and Neck|Lymphatic Metastasis|Down-Regulation|Head and Neck Neoplasms 68 LAD1 30108155 J. Lipid Res. 2018 PMC6168314 10.1194/jlr.P080218 4 0 0 596 Humans|*Genome-Wide Association Study|*Arabs|*Hypertriglyceridemia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Recessive Gene|Phenotype|European Continental Ancestry Group|Lipids|Kuwait 84 LAD1 30078245 Zhonghua Er Ke Za Zhi 2018 10.3760/cma.j.issn.0578-1310.2018.08.012 1 0 0 596 84 LAD1 30041527 Arch Iran Med 2018 0 0 0 596 Humans|Leukocyte adhesion deficiency type 1|Leukocyte-Adhesion Deficiency Syndrome|*CD18 Antigens|*Integrins|*Cell Adhesion|Mutations|Mutation, Missense|Leukocytes 84 LAD1 29976735 Haematologica 2018 PMC6278969 10.3324/haematol.2018.195867 4 1 0 596 Humans|*Mastocytosis, Systemic|Proto-Oncogene Proteins c-kit|Mast Cells|Protein Kinase Inhibitors|Mutation|Blotting, Western|Flow Cytometry 84 LAD1 29382783 Sci Signal 2018 10.1126/scisignal.aan0949 6 1 0 596 Humans|Animals|*Epidermal Growth Factor|*Actins|*Filamins|Cell Migration|Receptor, ErbB-2|Phosphorylation|*Protein Binding|Actin Cytoskeleton|Cell Proliferation|Signal Transduction|Cell Line, Tumor|Pathway, ERK|Cells, Epithelial|*Breast Cancer 84 LAMP3 30294508 PeerJ 2018 PMC6170155 10.7717/peerj.5590 2 6 0 91 Humans|Female|*Uterine Cervical Neoplasms|RNA, Ribosomal, 16S|Human Papilloma Virus|*Bacteria|Papillomavirus Infections|Microbiota|Cervix Uteri|*Gene Expression|Carcinogenesis|Network, Gene 124 laptm5 30523150 J. Biol. Chem. 2018 PMC6349094 10.1074/jbc.RA118.005993 4 2 0 113 N-Acetylglucosaminyltransferases|beta-N-Acetylhexosaminidases|Acetylglucosamine|Protein Processing, Post-Translational 49 laptm5 30253787 J Neuroinflammation 2018 PMC6156955 10.1186/s12974-018-1316-0 4 0 0 113 Rats|Animals|*Transcriptome|*Constriction|*Horn, Dorsal|*Sequencing, RNA|Pain, Neuropathic|Rats, Sprague-Dawley|Gene Expression Profiling|*Base Sequence|RNA, Messenger|*Whole Exome Sequencing|*Crush Injuries|Disease Models, Animal 49 LARP6 30354209 Arterioscler. Thromb. Vasc. Biol. 2018 PMC6287936 10.1161/ATVBAHA.118.311134 6 5 0 495 Mice|Animals|IGF1 protein, human|*Insulin-Like Growth Factor I|*Muscle Protein|*Atherosclerosis|*Receptor, IGF Type 1|Atherosclerotic Plaque|Apo E|IGF1R protein, human|*Receptors, Somatomedin|Muscle, Smooth, Vascular|Myocytes, Smooth Muscle|Aortic Diseases|Aorta|Insulin-Like Growth Factor I, Resistance To|*Growth Disorders|*Abnormalities, Multiple|Mice, Inbred C57BL|Cells, Cultured 35 LBX2 30514397 Acta Neuropathol Commun 2018 PMC6278135 10.1186/s40478-018-0630-1 4 0 0 16 Child|Humans|Familial ependymoma|*Ependymomas|*Supratentorial Neoplasms|Glioma|Transcription Factor RelA|Brain Neoplasms|*Genes, Regulator|Oncogene Proteins, Fusion|Genetic Profile|Japan|CRIP1 protein, human|Carrier Proteins|LIM Domain Proteins|RELA protein, human|C11orf95 protein, human|Proteins 34 LBX2 30069164 Cancer Cell Int. 2018 PMC6064140 10.1186/s12935-018-0603-2 8 13 0 16 Humans|*RNA, Long Noncoding|*Prognosis|*Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Mutation|Biomarkers 34 LBX2 29669692 Int. J. Cardiol. 2018 10.1016/j.ijcard.2018.04.038 1 0 0 16 Humans|*Atrial Septal Defect|Homeobox Protein Nkx-2.5|Chinese|Exons|Homeodomain Proteins|Pedigree|Mutation|Genetic Predisposition to Disease|Transcription Factors|Heart Defects, Congenital|Amino Acid Sequence 34 LGALS12 30504378 Anticancer Res. 2018 10.21873/anticanres.13037 0 1 0 461 hexosaminidase C|beta-N-Acetylhexosaminidases|O-GlcNAc transferase|N-Acetylglucosaminyltransferases|Acetylglucosamine|Protein Processing, Post-Translational|Glucosamine 24 LGALS12 30165571 Acta Biochim. Biophys. Sin. (Shanghai) 2018 10.1093/abbs/gmy099 1 3 0 461 Mice|Swine|Animals|*Adipogenesis|*Adipocyte|Lipolysis|*Signal Transduction|3T3-L1 Cells|*ERK1-2 Pathway|Lipase, Hormone-Sensitive|Subcutaneous Fat|PPAR gamma|Cyclic AMP-Dependent Protein Kinases|Adipose Tissue|Cell Differentiation|Phosphorylation|Lipogenesis|RNA, Small Interfering|Lipase 24 LGALS12 29976086 Am. J. Chin. Med. 2018 10.1142/S0192415X18500544 0 0 0 461 Mice|Animals|*Zea mays|*Adipogenesis|3T3-L1 Cells|*Obesity|Adipocytes|Anti-Obesity Agents|CCAAT-Enhancer-Binding Proteins|Cell Differentiation|PPAR gamma|Diet, High-Fat|CCAAT-Enhancer-Binding Protein-alpha|Adipose Tissue|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Plant Extracts|Proto-Oncogene Proteins c-akt|Signal Transduction|Silk 24 LHX1 30529537 Genomics 2018 10.1016/j.ygeno.2018.11.029 1 0 0 295 *DNA Copy Number Variations|*PCR, Multiplex|Comparative Genomic Hybridization|Genetic Loci 295 LHX1 30375416 Sci Rep 2018 PMC6207768 10.1038/s41598-018-34038-x 1 1 0 295 Animals|LHX1 protein, human|LIM-Homeodomain Proteins|Transcription Factor|Homeodomain Proteins|Xenopus laevis|Xenopus Proteins|Gene Expression Regulation, Developmental|Mesoderm|*Organogenesis|Embryo, Nonmammalian|MicroRNAs 295 LHX1 30215278 Cell Transplant 2018 PMC6180718 10.1177/0963689718797053 1 4 0 295 Male|Mice|Animals|*Mouse Embryonic Stem Cells|Cell Differentiation|Sertoli Cells|Intermediate Mesoderm|Embryonic Stem Cell|Spermatogenesis|PAX2 Transcription Factor|Cell Line|Transcription Factors 295 LHX1 30114334 Genesis 2018 10.1002/dvg.23246 1 0 0 295 Mice|Animals|*Gene Regulatory Networks|*Genes, Homeobox|*Embryonic Development|LIM-Homeodomain Proteins|Transcription Factors|Embryo, Mammalian|Germ Layers|Homeodomain Proteins|Gene Expression Regulation, Developmental|Xenopus Proteins|*Head|Xenopus laevis 295 LHX5 29397531 Cerebellum 2018 PMC6028833 10.1007/s12311-017-0913-2 4 5 0 58 Mice|Animals|Humans|*Purkinje Cells|*Induced Pluripotent Stem Cells|Cerebellum|Neurons|Cell Differentiation|Cell Culture Techniques|Co-culture|Neurogenesis|Cells, Cultured|Pluripotent Stem Cells|En1 protein, mouse|Homeodomain Proteins 61 LIM2 30288570 Knee Surg Sports Traumatol Arthrosc 2018 10.1007/s00167-018-5169-y 0 0 0 80 Humans|*Arthroplasty, Replacement, Knee|*Survivorship|Knee Prosthesis|Joint, Patellofemoral|Osteoarthritis, Knee|Knee Joint|Prosthesis Failure|Treatment Outcome|*Bone Diseases 116 LIM2 29751158 Aquat. Toxicol. 2018 10.1016/j.aquatox.2018.04.012 1 2 0 80 Animals|*Zebrafish|*Myofibrils|*Water|Embryo, Nonmammalian|Larva|Tritium|Water Pollutants, Chemical|DNA Repair 116 LIM2 29377145 J. Med. Primatol. 2018 10.1111/jmp.12332 0 0 0 80 Animals|Chlorocebus aethiops|*Cataract|Pedigree|Mutation, Missense|*Breeding 116 LIMA1 30378387 Int. J. Dev. Biol. 2018 10.1387/ijdb.180110tm 0 0 0 489 Humans|Animals|*Actins|*Fluorescence Resonance Energy Transfer|HeLa Cells|Xenopus laevis|Morphogenesis|Neural Tube|Neurulation|Ectoderm|Embryogenesis|Mechanical Phenomena|*Vibration|Biomechanical Phenomena|Embryo, Mammalian|LIMA1 protein, human|Cytoskeletal Proteins 43 LIMA1 30098000 Int. J. Cancer 2018 10.1002/ijc.31786 1 3 0 489 Humans|Male|*Prostate Cancer|Cell Movement|PXN protein, human|Paxillin|Signal Transduction|Focal Adhesion Kinase 1|src-Family Kinases|Cell Line, Tumor|Downregulation|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cytoskeletal Proteins|Phosphorylation|shRNA|Transfection 43 LIMA1 29880681 Science 2018 10.1126/science.aao6575 5 0 0 489 Humans|Low Density Lipoprotein Cholesterol|Hypercholesterolemia|Receptors, LDL|Membrane Proteins 43 LINC00958 30568497 Cancer Manag Res 2018 PMC6267766 10.2147/CMAR.S186108 11 0 0 0 *Long Non-Coding RNA|*Urinary Bladder Neoplasms|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Exosomes|Cell Line, Tumor|Biomarkers, Tumor|Signal Transduction|*Urinary Tract|Tumor Microenvironment 21 LINC00958 29570358 DNA Cell Biol. 2018 10.1089/dna.2018.4163 10 1 0 0 Humans|*RNA, Long Noncoding|Glioma|Cell Proliferation|CDK2 protein, human|*Cyclin-Dependent Kinase 2|Brain Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|MicroRNAs|Tumorigenesis|Cell Movement|Cell Line, Tumor|Cell Transformation, Neoplastic|Oncogenes|*Genes, cdc|Apoptosis|3' Untranslated Region|Upregulation 21 LINC00958 29355840 J. Clin. Invest. 2018 PMC5785244 10.1172/JCI96218 31 4 0 0 Humans|Mice|Animals|*Lymphangiogenesis|*RNA, Long Noncoding|*Lymphatic Metastasis|*Urinary Bladder Neoplasms|VEGF-C|Gene Expression Regulation, Neoplastic|Upregulation|Prognosis|Cell Line, Tumor|Signal Transduction|2,5-dichloro-4-bromophenol|*Chlorophenols|WDR5 protein, human|Histone-Lysine N-Methyltransferase 21 Lingo2 30567476 J Bioinform Comput Biol 2018 10.1142/S0219720018400267 6 0 0 36 Genome-Wide Association Study|Models, Genetic|Traits, Complex|Algorithms|Computer Simulation|*Epistasis, Genetic|Genome|Single Nucleotide Polymorphisms 31 Lingo2 30426492 J. Cell. Physiol. 2018 10.1002/jcp.27454 1 0 0 36 Pregnancy|Humans|Female|*Diabetes, Gestational|Case-Control Studies|Genome-Wide Association Study|Diabetes Mellitus, Type 2|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Gene Frequency|Genotype|Alleles|Body Mass Index|Odds Ratio 31 Lingo2 29700853 J. Anim. Breed. Genet. 2018 10.1111/jbg.12325 1 0 0 36 Cattle|Animals|*Agonistic Behavior|Breeding|Genotype|Phenotype|Selection, Genetic|Genomics|Gene Frequency|Quantitative Trait Loci|Chromosome Mapping|Polymorphism, Single Nucleotide|Allele 31 Lingo2 29672870 Anim. Genet. 2018 10.1111/age.12664 2 0 0 36 Animals|*Genome-Wide Association Study|*Chickens|*Sex Chromosomes|Feathers|Phenotype|Breeding|Polymorphism, Single Nucleotide 31 LMTK2 29631601 Mol Brain 2018 PMC5891947 10.1186/s13041-018-0363-x 5 52 0 253 Animals|Mice|*TYK2 Kinase|*Lemur|*Protein-Serine-Threonine Kinases|tau Proteins|Alzheimer Disease|Axonal Transport|Phosphorylation|Nerve Degeneration|Membrane Proteins|Disease Models, Animal 47 LPHN2 30340542 Acta Neuropathol Commun 2018 PMC6195752 10.1186/s40478-018-0610-5 2 1 0 177 Chick Embryo|Humans|Animals|Mice|*Microcephaly|HeLa Cells|*Cerebellar Diseases|Cerebellum|Agenesis of Corpus Callosum|Brain|Rhombencephalon|Whole Exome Sequencing|*Anencephaly|Phenotype|Mutation|Mesencephalon 29 LPHN2 30033078 Lancet Haematol 2018 PMC6069675 10.1016/S2352-3026(18)30107-8 13 0 0 177 Child|Humans|Kenya|*Case-Control Study|*Malaria|Plasmodium falciparum Malaria|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Red Blood Cells|Phenotypes|Sickle Cell Trait|Anemia 29 LPHN2 29290962 Oncotarget 2018 PMC5739747 10.18632/oncotarget.22461 0 3 0 177 Humans|Female|*Paclitaxel|*Neoadjuvant Therapy|*Pharmacogenetics|Receptor, ErbB-2|Antineoplastic Combined Chemotherapy Protocols|Doxorubicin|Tumor 29 LRIG3 30429017 Lung Cancer 2018 10.1016/j.lungcan.2018.09.017 1 3 0 135 Humans|*Prognosis|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Integral Membrane Proteins|Membrane Glycoproteins|Biomarkers, Tumor|Genes, Tumor Suppressor|Downregulation|LMO7 protein, human|Transcription Factors|LIM Domain Proteins|LRIG1 protein, human|LIMCH1 protein, human 50 LRIG3 30412760 Int. J. Biol. Macromol. 2018 10.1016/j.ijbiomac.2018.11.028 1 1 0 135 Humans|Male|*Prostate Cancer|siRNA|Neoplasm Invasiveness|RNA Interference|Cell Movement|Apoptosis|Cell Proliferation|Cell Line, Tumor|mRNA|Membrane Proteins|LRIG3 protein, human 50 LRIG3 29317492 J. Biol. Chem. 2018 PMC5836135 10.1074/jbc.M117.807487 5 34 0 135 Humans|*Leucine|*Protein Interaction Maps|HEK293 Cells|*Growth Factor Receptors|ErbB Receptors|*Immunoglobulin-like Domains|Membrane Glycoproteins|Membrane Proteins|Downregulation|Genes, Tumor Suppressor|Receptor Protein-Tyrosine Kinases|Signal Transduction|Cell Line, Tumor|*Protein Domains|GLRX3 protein, human|Carrier Proteins|LRIG1 protein, human 50 LRRC26 29713287 Front Physiol 2018 PMC5911984 10.3389/fphys.2018.00312 2 32 0 54 *Proteolysis|*Gene Expression|Large-Conductance Calcium-Activated Potassium Channel alpha Subunits|Cell Line, Tumor|Receptors, Androgen|Down-Regulation|Cell Proliferation 29 LRRC26 29570902 Cell Biol. Int. 2018 10.1002/cbin.10962 0 2 0 54 Mice|Animals|*Oestradiol|*Transcriptome|Myoblasts|*Cell Differentiation|*Estrogens|Muscle Development|nonmuscle myosin type IIB heavy chain|Myosin Heavy Chain|Muscle Proteins|LIM Domain Proteins|Downregulation|Intracellular Signaling Peptides and Proteins|Cell Line|Up-Regulation|Nonmuscle Myosin Type IIB 29 LRRC26 29512727 Int. J. Oncol. 2018 10.3892/ijo.2018.4301 1 3 0 54 Humans|*Triple-Negative Breast Cancer|*Down-Regulation|Signal Transduction|Cell Movement|Cell Proliferation|Cell Line, Tumor|Viability, Cell|RNA, Small Interfering|Epidermal Growth Factor|*Disease Progression|Interleukin 6|Epigenesis, Genetic|LRRC26 protein, human|Neoplasm Proteins 29 lrrc32 30443770 Endocr. Pathol. 2018 10.1007/s12022-018-9557-0 1 0 0 51 Humans|*Thyroid Cancer, Papillary|Carcinoma, Papillary|Thyroid Neoplasms|Goiter, Nodular|Lymphatic Metastasis|Thyroid Gland|Carcinoma|T-Cells, Regulatory|Immunohistochemistry|Forkhead Transcription Factors|Prognosis|Thyroid Diseases|Biomarkers, Tumor|*Glycoprotein 128 lrrc32 30373671 Respir. Res. 2018 PMC6206739 10.1186/s12931-018-0890-0 5 0 0 51 Humans|Adult|Child|*Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|*Asthma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Lung|Smoking|Smokers|Risk Factor 128 lrrc32 30371828 Mol. Hum. Reprod. 2018 PMC6262632 10.1093/molehr/gay044 2 9 0 51 Humans|Pregnancy|Female|Mice|Animals|*Pregnancy-Specific beta 1-Glycoproteins|*Transforming Growth Factor|Transforming Growth Factor beta1 128 lrrc32 30361387 Science 2018 10.1126/science.aau2909 14 0 0 51 Humans|*T-Lymphocytes, Regulatory|Forkhead Transcription Factors|*Transforming Growth Factor|Transforming Growth Factor beta1|Lymphocyte Activation|Membrane Proteins|Integrins|Cytokines|Protein Binding 128 lrrc32 30224551 Infect. Immun. 2018 PMC6246916 10.1128/IAI.00432-18 0 3 0 51 Mice|Animals|*Soft Tissue Infections|*Disease Models, Animal|*T-Cells, Regulatory|Forkhead Transcription Factors|Lymphocyte Activation|*Streptococcus pyogenes|Transforming Growth Factor beta|Cytokines|Membrane Proteins|Superantigens|Streptococcal Infections|Foxp3 protein, mouse 128 lrrc32 30219744 Mult Scler Relat Disord 2018 10.1016/j.msard.2018.08.009 3 0 0 51 Humans|*Rapamycin|*Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|Immunosuppressive Agents|T-Cells, Regulatory|Forkhead Transcription Factors|Imaging, Magnetic Resonance|Brain|India 128 LRWD1 29544732 Biochimie 2018 10.1016/j.biochi.2018.03.001 0 2 0 85 Humans|*Embryonal Carcinoma Stem Cells|*Oxidative Stress|NF-E2-Related Factor 2|Reactive Oxygen Species|Heme Oxygenase-1|Hydrogen Peroxide|Gene Expression Regulation|Signal Transduction|Cell Line|Embryonal Carcinoma|*Acclimatization|LRWD1 protein, human|Microtubule Proteins 22 LSG1 29679561 Dev. Biol. 2018 PMC6278609 10.1016/j.ydbio.2018.04.014 1 39 0 94 Animals|*Larvae|nucleostemin 3, Drosophila|*Drosophila Proteins|*Neurogenesis|Neural Stem Cells|Drosophila melanogaster|Cell Differentiation|*GTP-Binding Proteins|Cell Division|Drosophila|Cell Polarity|Neurons|Asymmetric Cell Division|Cell Cycle Proteins|Gene Expression Regulation, Developmental|Cell Cycle|Cell Proliferation 26 LSG1 29536998 Phys Chem Chem Phys 2018 10.1039/c7cp08223a 0 0 0 94 Electrolytes|Electricity|*Edible Grain 26 LTK 30586377 PLoS ONE 2018 PMC6306251 10.1371/journal.pone.0208821 1 1 0 121 Mice|Animals|*Soy Foods|Tetragenococcus halophilus|*Enterococcaceae|Fermentations|Fermentors|Lactic Acid 669 LTK 30286071 PLoS Genet. 2018 PMC6191144 10.1371/journal.pgen.1007402 4 1 0 121 Animals|*Neural Crest|*Gene Regulatory Networks|*Systems Biology|Zebrafish|Zebrafish Proteins|SOXE Transcription Factors|Chromatophores|Melanocytes|Gene Expression Regulation, Developmental|Microphthalmia-Associated Transcription Factor|Forkhead Transcription Factors|Ltk protein, zebrafish|Protein-Tyrosine Kinases 669 LTK 30228102 Development 2018 PMC6215395 10.1242/dev.164046 2 2 0 121 Animals|Chick Embryo|*Neural Crest|MDK protein, human|*Midkine|*Cell Movement|*Cell Differentiation|Ectoderm|*Leukocytes|Body Patterning|Embryo, Nonmammalian|Receptor Protein-Tyrosine Kinases|*Organogenesis|Melanocytes 669 LTK 30061385 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6099872 10.1073/pnas.1807881115 3 5 0 121 Humans|Mice|Rats|Animals|*Anaplastic Lymphoma Kinase|*Ligands|*Tyrosine Kinase 2|LTK protein, human|Receptor Protein-Tyrosine Kinases|Protein Binding|Phosphorylation|Protein-Tyrosine Kinases|Amino Acid Sequence|PC12 Cells|Neuroblastoma 669 LTK 29747401 Int J Mol Sci 2018 PMC5983725 10.3390/ijms19051414 3 9 0 121 *Epigenome|*Stress, Heat|Gene Expression Regulation, Plant|RNA, Plant|Genes, Plant|Genome, Plant|Epigenesis, Genetic|DNA Methylation|Transposable Elements|*Heat Stress Disorders|Stress, Physiological|Cytosine|Gene Expression Profiling 669 LTK 29317532 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC5789956 10.1073/pnas.1719137115 15 15 0 121 Humans|Animals|Child|ALK protein, human|*Anaplastic Lymphoma Receptor Tyrosine Kinase|*Neural Crest|*Ligands|LTK protein, human|Receptor Protein-Tyrosine Kinases|Zebrafish|Amino Acid Sequence|Mutations|Tyrosine|Ltk protein, zebrafish|Protein-Tyrosine Kinases|Zebrafish Proteins 669 LTK 29312610 Oncotarget 2018 PMC5752523 10.18632/oncotarget.22674 1 32 0 121 Humans|AZD 1480|*Receptor Protein-Tyrosine Kinases|*Pyrimidines|*Pyrazoles|Anaplastic Lymphoma Kinase|Protein Kinase Inhibitors|Carcinoma, Non-Small-Cell Lung|JAK2 protein, human|Janus Kinase 2|Lung Neoplasms|Xenograft Model Antitumor Assays|Cell Line, Tumor|RET protein, human|Proto-Oncogene Proteins c-ret|LTK protein, human 669 Ly75 30518881 Sci Rep 2018 PMC6281609 10.1038/s41598-018-36073-0 0 0 0 198 Mice|Animals|*Obesity|Body Weight|*Phenotype|Quantitative Trait Locus|Chromosome Mapping|Lectins, C-Type|Crosses, Genetic|Genotype|Antigens, CD|Minor Histocompatibility Antigens|Fat Pads 29 Ly75 30102794 Pediatr Allergy Immunol 2018 10.1111/pai.12971 0 2 0 198 Child|Humans|Asthma|Cytokines|Leukocytes, Mononuclear|Phenotypes|Up-Regulation|Case-Control Studies 29 Ly75 29593811 Arch Med Sci 2018 PMC5868677 10.5114/aoms.2018.73469 0 4 0 198 Humans|*Scleroderma, Localized|*T-Lymphocytes, Regulatory|*Skin|*Phototherapy|Ultraviolet Therapy|IL17A protein, human|Interleukin 17A|Cytokines|RNA, Messenger|Dendritic Cells 29 Ly75 29524808 Theriogenology 2018 10.1016/j.theriogenology.2017.12.016 1 0 0 198 Male|Animals|*Spermatogonia|*Scophthalmus maximus|Gonads|Lectins, C-Type|Testes|*Biomarkers|Zebrafish Proteins|Antigens, CD|In Situ Hybridization|Minor Histocompatibility Antigens|Gene Expression Regulation, Developmental|mRNA|Lymphocytes 29 LYAR 30553890 Fish Shellfish Immunol. 2018 10.1016/j.fsi.2018.12.021 1 0 0 134 Animals|*Palaemonidae|*Hemocytes|Nodaviridae|ferrous fumarate|*Ferrous Compounds|*Hematopoiesis|Transcriptome|Immunity|Hematopoietic Stem Cell Transplantation|Infections 32 LYAR 30209172 J. Virol. 2018 PMC6232469 10.1128/JVI.01042-18 4 1 0 134 Humans|Dogs|Animals|*Influenza A virus|Virus Replication|RNA, Viral|Influenza, Human|Ribonucleoprotein|Host-Pathogen Interactions|Viral Assembly|Madin Darby Canine Kidney Cells|Antiviral Agents|A549 Cells|Protein Binding|HEK293 Cells|Viral Genome|*Cell Nucleolus|LYAR protein, human|DNA-Binding Proteins|Nuclear Proteins 32 LYAR 29722257 ACS Appl Mater Interfaces 2018 10.1021/acsami.8b05428 0 0 0 134 Humans|graphene oxide|*Graphite|Carbon Nanotube|Nanomaterials|Proteins|Proteomics|*Lung Cancer 32 LYAR 29505757 J. Mol. Biol. 2018 10.1016/j.jmb.2018.02.023 3 0 0 134 Animals|*Chromatin|BRDT protein, human|BRD4 protein, human|Nuclear Proteins|*Transcription Factors|*Down-Regulation|*Cell Differentiation|Protein-Serine-Threonine Kinases|Promoter Regions, Genetic|Cell Cycle|Gene Expression Regulation|Protein Binding 32 LYL1 30185409 Development 2018 10.1242/dev.162990 0 2 0 118 T-Cell Acute Lymphocytic Leukemia Protein 1|GATA1 Transcription Factor|Basic Helix-Loop-Helix Transcription Factors|Erythroid Cells|Erythropoiesis|Proto-Oncogene Proteins 92 LYL1 30115950 J. Hum. Genet. 2018 10.1038/s10038-018-0496-x 4 0 0 118 Humans|*Whole Exome Sequencing|*Basilar Artery|*Vertebral Artery Dissection|Mutations|Sequence Analysis, DNA|Genetic Predisposition to Disease|Phenotype|Mutation Rate|*Cohort Studies 92 LYL1 29716549 BMC Cancer 2018 PMC5930686 10.1186/s12885-018-4429-z 2 0 0 118 Humans|Female|*Gene Amplification|*Carcinoma, Endometrioid|Endometrial Neoplasms|Prognosis|Disease-Free Survival|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Mutation|LYL1 protein, human|Neoplasm Proteins|Basic Helix-Loop-Helix Transcription Factors 92 LYL1 29555020 Elife 2018 PMC5860872 10.7554/eLife.29312 4 8 0 118 Mice|Animals|*Transcriptome|*Hematopoiesis|TAL1 protein, human|T-Cell Acute Lymphocytic Leukemia Protein 1|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|LYL1 protein, human|Basic Helix-Loop-Helix Transcription Factors|GATA2 protein, human|GATA2 Transcription Factor|Cell Differentiation|Hematopoietic Stem Cells|LIM Domain Proteins|Neoplasm Proteins|Proto-Oncogene Protein c-fli-1|*B-Lymphocytes|Proto-Oncogene Proteins|Gene Expression Regulation, Developmental 92 LYL1 29382838 Sci Rep 2018 PMC5789843 10.1038/s41598-018-19527-3 1 9 0 118 *Oryza|geranylgeranyl reductase|*Oxidoreductases|Arabidopsis thaliana|Gene Expression Regulation, Plant|Chlorophyll|Plant Proteins|Plants, Genetically Modified|Tocopherol|Seeds|Plant Leaves|Vitamin E|Tocotrienol|Phenotype 92 LYNX1 30397527 Acta Naturae 2018 PMC6209405 1 2 0 3 Humans|*Long-Term Potentiation|Receptors, Nicotinic Acetylcholine|*Neuromodulator|GPI-Linked Proteins|Neurons|Brain|LYNX1 protein, human 78 LYNX1 30291908 Pharmacol. Ther. 2018 PMC6348061 10.1016/j.pharmthera.2018.10.002 5 3 0 3 Humans|*Acetylcholine|Electronic Nicotine Delivery Systems|Choline Acetyltransferase|*Lung Cancers|Nicotinic Receptor|*Signal Transduction|Muscarinic Receptors|choline transporter|Membrane Transport Proteins|*Disease Progression|Lung|Biological Transport|Choline|Nicotine|Acetylcholinesterase 78 LYNX1 29969495 PLoS ONE 2018 PMC6029753 10.1371/journal.pone.0199643 4 5 0 3 Animals|Mice|*Nicotinic Acetylcholine Receptor|Nicotine|*Cell Membrane|Neurons|GPI-Linked Proteins|Signal Transduction|Analgesics 78 LYNX1 29857015 Neurosci. Res. 2018 PMC6265126 10.1016/j.neures.2018.05.006 0 0 0 3 *Ribosome|enhanced green fluorescent protein|Green Fluorescent Proteins|*Electroporation|*Pyramidal Neurons|Neurons|Ribosomal Proteins|mRNA|Protein Biosynthesis|Gene Expression Profiling|Brain|Synapses|TCL1B protein, human|Transcription Factors|Somatosensory Cortex|DNA-Binding Proteins 78 LYNX1 29523067 Biochemistry Mosc. 2018 10.1134/S0006297917130090 5 0 0 3 Animals|PLAUR protein, human|*Receptors, Urokinase Plasminogen Activator|Antigens, Ly|TYRP1 protein, human|*Membrane Glycoproteins|Urokinase-Type Plasminogen Activator|Receptors, Nicotinic Acetylcholine|Amino Acid Sequence|Neurotoxins|Snake 78 LYNX1 29505672 Br. J. Pharmacol. 2018 PMC5980222 10.1111/bph.14194 7 5 0 3 Humans|*Receptors, Nicotinic Acetylcholine|TYRP1 protein, human|*Membrane Glycoproteins|Antigens, Ly|alpha7 Nicotinic Acetylcholine Receptor|Urokinase-Type Plasminogen Activator|Keratinocytes|*Biochemical Phenomena 78 LYNX1 29358666 Nat. Neurosci. 2018 PMC5978727 10.1038/s41593-017-0064-2 25 7 0 3 Mice|Animals|Parvalbumins|Interneurons|Primary Auditory Cortex|*Critical Period, Psychological|Excitatory Postsynaptic Potentials|Neural Inhibition|Visual Cortex|Thalamus|Synapses|Mice, Transgenic|Vasoactive Intestinal Peptide 78 MACROD2 30587500 Cancer Genomics Proteomics 2018 PMC6348402 10.21873/cgp.20112 0 0 0 58 Humans|*Poliovirus|*Genome, Human|Poliomyelitis|Poliovirus Vaccine, Oral|Genome, Viral|*Colorectal Cancer|*Colonic Neoplasms 79 MACROD2 30343302 Gynecol. Obstet. Invest. 2018 10.1159/000493131 2 0 0 58 Humans|Female|*Polycystic Ovary Syndrome|*Insulin Resistance|Genome-Wide Association Study|Republic of Korea|*Energy Intake|*Risk Factors|Insulin|Blood Glucose|Genetic Predisposition to Disease|Body Mass Index|Polymorphism, Single Nucleotide|CHRM3 protein, human|*Receptor, Muscarinic M3|Case-Control Studies|ASIC2 protein, human|*Acid Sensing Ion Channels|MACROD2 protein, human|Hydrolases 79 MACROD2 30267646 Biochem. Pharmacol. 2018 10.1016/j.bcp.2018.09.028 3 2 0 58 Animals|Mice|poly ADP-ribose glycohydrolase|Glycoside Hydrolases|ADP-Ribose|Poly Adenosine Diphosphate Ribose|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Ribosylations, ADP|O Acetyl ADP Ribose|*Cell Death|*Cell Transformation, Neoplastic|*Tumorigenesis|Hydrolysis|N-Glycosyl Hydrolases|Oxidative Stress|Catalysis|Amino Acid Sequence|Catalytic Domain|Protein Processing, Post-Translational 79 MAGEC1 30195627 Blood Cells Mol. Dis. 2018 10.1016/j.bcmd.2018.08.002 0 0 0 33 Male|Humans|Female|*Monoclonal Gammopathy of Undetermined Significance|In Situ Hybridization, Fluorescence|*Monoclonal Gammopathy|*Prognosis|Immunoglobulin M|Disease Progression|Amyloidosis|Interphase|Immunoglobulin Light-chain Amyloidosis|China 67 MAGEC1 30006881 Bull. Exp. Biol. Med. 2018 10.1007/s10517-018-4175-x 0 0 0 33 Humans|Male|Female|*Testis|MAGEA3 protein, human|Antigens, Neoplasm|Neoplasm Proteins|Melanoma-Specific Antigens|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Membrane Proteins|*Activation, Transcription|*Transcription Factors|Real-Time Polymerase Chain Reaction|Neoplasms|MAGEA4 protein, human|MAGEB2 protein, human|MageA2 protein, human 67 MAP3K10 30093562 Cancer Res. 2018 PMC6459603 10.1158/0008-5472.CAN-17-3912 3 2 0 161 Mice|Animals|*Tumorigenesis|*Cell Transformation, Neoplastic|Rhabdomyosarcoma, Alveolar|PAX3 Transcription Factor|*Rhabdomyosarcoma|Paired Box Transcription Factors|Forkhead Box Protein O1|Myoblasts|*Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic|Oncogene Proteins, Fusion|Chromosomal Translocation|Muscle Development|Cell Line, Tumor|Cell Differentiation 61 MAP3K10 30069494 Mol Ther Methods Clin Dev 2018 PMC6068090 10.1016/j.omtm.2018.06.007 4 6 0 161 *Protein Interaction Maps|Reproducibility of Results|*Algorithms|*Tumor Suppressor Genes|Computational Biology|Databases, Genetic|*Diffusion|Genes, Reporter 61 MAP3K10 29954663 Trends Immunol. 2018 PMC6528674 10.1016/j.it.2018.05.003 3 0 0 161 Humans|Mice|Animals|*Signal Transduction|Protein-Serine-Threonine Kinases|Phosphorylation|Cell Proliferation|*Leukocytes|Lymphocyte|Hippo protein, human 61 MAP3K10 29755656 Oncotarget 2018 PMC5945544 10.18632/oncotarget.24866 1 9 0 161 Humans|*Nanotubes, Carbon|Epigenesis, Genetic|Epithelial Cells|DNA Methylation|*Epigenetic|Cell Line 61 MAP3K10 29619976 Int. J. Radiat. Oncol. Biol. Phys. 2018 10.1016/j.ijrobp.2018.01.036 3 1 0 161 *Carcinoma, Non-Small-Cell Lung|*Necroptosis|*Lung Neoplasms|Necrosis|Receptor-Interacting Protein Serine-Threonine Kinases|Apoptosis|Signal Transduction|Imidazoles 61 MAP6 30236964 Neuropharmacology 2018 10.1016/j.neuropharm.2018.09.009 0 0 0 2068 Mice|Animals|*C57BL Mice|*Schizophrenia|MK 801|*Social Behavior|Antipsychotic Agents|Excitatory Amino Acid Antagonists|Ketamine|*Social Dominance|Cortex, Prefrontal|Social Interaction|*Communication|Disease Models, Animal|*Acoustic|*Dissociation|Cognition 78 MAP6 30231928 Skelet Muscle 2018 PMC6147105 10.1186/s13395-018-0176-8 3 0 0 2068 Mice|Animals|Mtap6 protein, mouse|Microtubule-Associated Proteins|Microtubules|*Muscle, Skeletal|Muscle Contraction|Muscle Fibers, Skeletal 78 MAP6 30224655 Nat Commun 2018 PMC6141585 10.1038/s41467-018-05869-z 1 4 0 2068 Mice|Animals|*Dendritic Spines|*Filaments, Actin|Microtubules|Neurons|Cytoskeleton|F-Actin|Microtubule-Associated Proteins|Synaptic Plasticity|Hippocampus|Phosphorylation|Cells, Cultured 78 MAP6 30146428 Brain Stimul 2018 10.1016/j.brs.2018.08.001 2 0 0 2068 Animals|Depressive Disorder, Major|*Depression|Electroconvulsive Therapy|Hippocampus|*Cell Survival|Neurons|Disease Models, Animal|*Cell Death 78 MAP6 30008334 Curr. Biol. 2018 10.1016/j.cub.2018.05.045 16 0 0 2068 Rats|Animals|*Microtubules|*Axons|*tau Proteins|Neurons|Tubulin|Hippocampus|Cells, Cultured 78 MAP6 29407391 Food Microbiol. 2018 10.1016/j.fm.2017.10.007 1 0 0 2068 Animals|Food Packaging|Food Preservation|Colony Count, Microbial|Food Microbiology|Vacuum|Refrigeration|Meat|*Struthioniformes|Food Contamination|*Drug Packaging|Bacteria|Odorants|Taste|Nitrogen 78 MAP9 30472874 Acta Virol. 2018 10.4149/av_2018_412 0 0 0 342 Humans|Animals|Mice|*Polymorphism, Single Nucleotide|*Herpesvirus 4, Human|Epstein-Barr Virus Infections|*Stomach Neoplasms|*Chinese|Allele Frequency|Genetic Predisposition to Disease|Carcinoma|Genotype|MAP9 protein, human|Microtubule-Associated Proteins 26 MAP9 30094535 J. Cancer Res. Clin. Oncol. 2018 10.1007/s00432-018-2710-9 6 2 0 342 Humans|Female|*Cytoskeletal Proteins|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Prognosis|Gene Expression Regulation, Neoplastic|Cytoskeleton|Microtubules|Cell Line, Tumor|RNA Interference|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate|Disease Progression|Cell Proliferation 26 MAP9 29934576 Sci Rep 2018 PMC6015020 10.1038/s41598-018-27826-y 2 12 0 342 Humans|*RNA Splicing|RNA Precursors|Alternative Splicing|Ribonucleoproteins|Exons|RNA-Binding Proteins|Introns|*Cell Nucleus|RNA, Messenger|Nuclear Proteins|HeLa Cells|Transcriptome Analysis 26 MATN2 30408806 Int. Arch. Allergy Immunol. 2018 10.1159/000493803 2 2 0 125 *Allergic Rhinitis|Macrophage Activation|Macrophages|MicroRNAs 55 MATN2 29946151 Nat Commun 2018 PMC6018668 10.1038/s41467-018-04908-z 14 11 0 125 Animals|Pregnancy|*T-Lymphocytes, Regulatory|*Myocytes, Cardiac|*Myocardial Infarction|Myocardium|Medium, Conditioned|Cell Proliferation|Cells, Cultured 55 MATN2 29775757 Gene 2018 PMC5994380 10.1016/j.gene.2018.05.034 3 0 0 125 Humans|Child|*Growth Plate|*Sequencing, RNA|Articular Cartilage|Chondrocytes|Matrilins|Extracellular Matrix Proteins|WNT10B protein, human|Wnt Proteins|Bone|Gene Expression Profiling|*Whole Exome Sequencing|Sequencing, Next-Generation|Signal Transduction|mRNA|Networks, Gene|Collagen|MATN2 protein, human 55 MCM9 30406445 J. Assist. Reprod. Genet. 2018 PMC6338598 10.1007/s10815-018-1349-4 1 0 0 93 Humans|Female|*Whole Exome Sequencing|*Menopause, Premature|*Primary Ovarian Insufficiency|Pedigree|Mutation 45 MCM9 30276597 J. Assist. Reprod. Genet. 2018 PMC6338603 10.1007/s10815-018-1325-z 1 0 0 93 Humans|Female|*Primary Ovarian Insufficiency|*Minichromosome Maintenance Complex Component 8|*Menopause, Premature|MCM8 protein, human|*Minichromosome Maintenance Proteins|*Menstrual Cycle|Follicular Phase|Luteal Phase|Menopause|*Gene Expression 45 MCTS1 30584092 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6329987 10.1073/pnas.1809688116 4 3 0 209 Humans|*Dimerization|*Zinc|MCTS1 protein, human|*Oncogene Proteins|*Cell Cycle Proteins|Ribosome|Eukaryotic Initiation Factors|*Binding Site|Protein Biosynthesis|mRNA|Open Reading Frames|*Protein Domains 66 MCTS1 30521130 Int. J. Cancer 2018 10.1002/ijc.32045 3 1 0 209 Humans|*Tumor Microenvironment|*Colorectal Cancer|lactate dehydrogenase 1|L-Lactate Dehydrogenase|Monocarboxylic Acid Transporters|Immunohistochemistry|Isoenzymes|*Colonic Neoplasms|Lactate Dehydrogenase 5|*Biomarkers 66 MCTS1 30146315 Mol. Cell 2018 PMC6225905 10.1016/j.molcel.2018.07.028 9 2 0 209 Ribosomes|Protein Biosynthesis|Stop Codon|Peptide Chain Initiation, Translational|40S Ribosomal Subunits|Peptide Chain Termination, Translational|Codon, Initiator|Open Reading Frames|Eukaryotic Initiation Factor-3|mRNA|MCTS1 protein, human|*Cell Cycle Proteins|Saccharomyces cerevisiae|*Oncogene Proteins|3' UTR 66 MCTS1 29889857 PLoS Biol. 2018 PMC6013234 10.1371/journal.pbio.2005160 0 9 0 209 Humans|*Dimerization|MCTS1 protein, human|*Oncogene Proteins|*Cell Cycle Proteins|*tRNA|Eukaryotic Initiation Factors|Ribosomes|mRNA|Open Reading Frame|Protein Biosynthesis|Eukaryotic Initiation Factor-2|*Protein Processing, Post-Translational 66 MCTS1 29678717 J Proteomics 2018 10.1016/j.jprot.2018.04.018 0 0 0 209 Rats|Animals|*Pancreatitis|*Proteomics|Acute Disease|Cerulein|Pancreas|Mitochondria|Lysosomes|Proteins|Disease Models, Animal 66 MCTS1 29534146 Acta Biochim. Biophys. Sin. (Shanghai) 2018 10.1093/abbs/gmy021 1 8 0 209 sotrastaurin|*Quinazolines|*Pyrroles|MCTS1 protein, human|*Cell Cycle Proteins|*Lymphoma, Large B-Cell, Diffuse|*Oncogene Proteins|PRKCB protein, human|*Protein Kinase C beta|Cell Proliferation|Apoptosis|Signal Transduction|Cell Cycle|Cell Line, Tumor|Phosphorylation|G1 Phase|siRNA 66 megf10 30451835 Nat Commun 2018 PMC6242819 10.1038/s41467-018-07291-x 3 0 0 113 Animals|Caenorhabditis elegans|Axons|Nerve Regeneration|Caenorhabditis elegans Proteins|*Neurons|rac GTP-Binding Proteins|Cytoskeletal Proteins|Signal Transduction|Carrier Proteins|Animals, Genetically Modified|Membrane Proteins|*B Cells|Apoptosis|ced-1 protein, C elegans 60 megf10 30221345 Clin. Genet. 2018 10.1111/cge.13448 3 0 0 113 Humans|Child|*Intellectual Disability|*Phenotypes|Whole Exome Sequencing|Facies|Pedigree|Exome|Genetic Association Studies|Mutation|Alleles|*Rare Diseases|High-Throughput Nucleotide Sequencing|Epilepsy|Genomics|ALMS1 protein, human|Proteins|FLVCR2 protein, human|Receptors, Virus|Membrane Transport Proteins 60 megf10 30194072 Genetics 2018 PMC6218217 10.1534/genetics.118.301500 1 29 0 113 Animals|Caenorhabditis elegans Proteins|Caenorhabditis elegans|Caspases|Apoptosis|Protein-Serine-Threonine Kinases 60 megf10 29887919 Dis. Markers 2018 PMC5985127 10.1155/2018/5975216 0 3 0 113 *Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Prognosis|DNA Methylation|Mutation|Promoter Regions, Genetic|Biomarkers, Tumor 60 megf10 29862966 Elife 2018 PMC6008046 10.7554/eLife.36688 13 0 0 113 Humans|Mice|Animals|*Receptors, Chimeric Antigen|Therapies, CAR T-Cell|Antigens, CD19|T Cells|Cytotoxicity, Immunologic|Lymphocyte Activation|*Phagocytosis|Antigens, Neoplasm|Immunoglobulin Fragments 60 megf10 29859070 BMC Oral Health 2018 PMC5984765 10.1186/s12903-018-0559-6 0 0 0 113 Child|Adult|Humans|Dental Caries|Genome-Wide Association Study|Dentition, Permanent|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|DMF Index|Genetic Variation|Tooth, Deciduous 60 megf10 29611808 Elife 2018 PMC5931800 10.7554/eLife.34241 7 0 0 113 Mice|Animals|Humans|Infant, Newborn|*Amacrine Cells|*Retina|Retinal Ganglion Cells|Visual Pathways|Dendrites|Synapses|Neural Inhibition|gamma-Aminobutyric Acid 60 megf10 29520845 Glia 2018 10.1002/glia.23322 4 0 0 113 Animals|*Drosophila|*Glia|*Phagocytosis|Drosophila Proteins|Drosophila melanogaster|Neurons|*Metamorphosis, Biological|Central Nervous System|Signal Transduction|*MAP Kinase Signaling System|Membrane Proteins|Axons|Apoptosis|Macrophages|Embryogenesis|Draper protein, Drosophila 60 megf10 29503163 Lancet Psychiatry 2018 10.1016/S2215-0366(18)30049-X 17 0 0 113 Humans|*Antipsychotic Agents|*Genome-Wide Association Study|*Schizophrenia|Risperidone|Olanzapine|Benzodiazepines|Pharmacogenetics|Polymorphism, Single Nucleotide|Genotype 60 megf10 29316776 Biomol Ther (Seoul) 2018 PMC6029679 10.4062/biomolther.2017.133 11 11 0 113 *Cells, Glial|Astrocytes|Microglia|*Brain|Synapses|Phagocytosis|*Phagocytes|Neurodegenerative Diseases|MERTK|Classical Complement Pathway 60 METRN 30213948 Exp. Mol. Med. 2018 PMC6137187 10.1038/s12276-018-0147-5 7 51 0 47 Mice|Animals|*Insulin Resistance|*AMP-Activated Protein Kinases|*Peroxisome Proliferator-Activated Receptors|*Muscle, Skeletal|*Inflammation|Diet, High-Fat|Insulin|Palmitates|Carnitine Palmitoyltransferase I|Signal Transduction|Obesity|Phosphorylation|Physical Conditioning, Animal|Diabetes Mellitus|Mice, Inbred C57BL 22 METRN 29930739 Theranostics 2018 PMC6010990 10.7150/thno.25156 7 8 0 47 *RNA, Circular|*Retina|Ependymoglial Cells|MicroRNAs|Glaucoma|Noncoding RNA|Apoptosis 22 MFSD8 30543658 PLoS ONE 2018 PMC6292620 10.1371/journal.pone.0207958 8 0 0 93 Humans|Female|Adolescent|*Retinitis Pigmentosa|*Next Generation Sequencing|Usher syndrome, type 2A|Usher Syndromes|*Genotype-Phenotype Correlations|Mutation|Eye Proteins|Retinal Dystrophies|Pedigree|Genes, X-Linked|PRPF31 protein, human 51 MFSD8 30382371 Acta Neuropathol. 2018 PMC6371791 10.1007/s00401-018-1925-9 5 0 0 93 Humans|Aged|*Neuronal Ceroid-Lipofuscinoses|*Frontotemporal Dementia|*Risk Factors|*Pick Disease of the Brain|Frontotemporal Lobar Degeneration|Progranulins|Intercellular Signaling Peptides and Proteins|Homozygote|Lysosomes|Mutations|MFSD8 protein, human|Membrane Transport Proteins|Neurons|Study, Genetic Association|Case-Control Study|C9orf72 protein, human|C9orf72 Protein 51 MFSD8 30301600 Mol. Genet. Metab. 2018 10.1016/j.ymgme.2018.09.009 2 3 0 93 Animals|Humans|Child|*Cell Survival|Ceroid Lipofuscinosis, Neuronal, 7|*Neuronal Ceroid-Lipofuscinoses|*Lysosome|*Neurons|Membrane Transport Proteins|Membrane Protein|Intracellular Membranes|Mutations|Central Nervous System|Disease Models, Animal|Cell Line 51 MFSD8 30249282 J Med Case Rep 2018 PMC6154911 10.1186/s13256-018-1788-7 0 1 0 93 Humans|Adult|Ceroid Lipofuscinosis, Neuronal, 7|*Neuronal Ceroid-Lipofuscinoses|*Whole Exome Sequencing|Iran|Pedigree|*Reading Frames|Membrane Transport Proteins|Mutation|Lysosomes|MFSD8 protein, human 51 MFSD8 30144815 BMC Med. Genet. 2018 PMC6109285 10.1186/s12881-018-0669-7 1 0 0 93 Child|Humans|Ceroid Lipofuscinosis, Neuronal, 7|*Neuronal Ceroid-Lipofuscinoses|Russia|MFSD8 protein, human|*Membrane Transport Proteins|Homozygote|Mutations|Pedigree|Seizures|Ataxia 51 MFSD8 30048804 Neurobiol. Dis. 2018 PMC6200145 10.1016/j.nbd.2018.07.013 2 1 0 93 Animals|*Neuronal Ceroid-Lipofuscinoses|*Primates|Membrane Transport Proteins|Homozygote|Disease Models, Animal|Brain|Mutation 51 MFSD8 29514215 Hum. Mol. Genet. 2018 PMC5932567 10.1093/hmg/ddy076 7 21 0 93 Animals|Mice|Humans|Ceroid lipofuscinosis, neuronal 5|Ceroid Lipofuscinosis, Neuronal, 7|*Neuronal Ceroid-Lipofuscinoses|lysosomal proteins|Lysosomes|MTOR protein, human|*TOR Serine-Threonine Kinases|Membrane Proteins, Lysosomal|Membrane Protein|Membrane Transport Proteins|Lysosomal Storage Diseases|Knockout Mouse|Protein Transport|Intracellular Membranes|Proteolysis|Protein Processing, Post-Translational|Cln5 protein, mouse|Membrane Glycoproteins 51 MICAL2 30555547 Theranostics 2018 PMC6276083 10.7150/thno.28228 2 1 0 153 Humans|*Ubiquitin|*Tumor Suppressor Protein p53|*Methionine|*Colorectal Cancer|*Racemethionine|HCT116 Cells|Carcinogenesis|Prognosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Ubiquitination|Cell Line, Tumor|Apoptosis|Cell Movement|Gene Knockdown Techniques 22 MICAL2 29951943 Horm Cancer 2018 10.1007/s12672-018-0337-6 0 0 0 153 Humans|Female|*Carboplatin|*Paclitaxel|*Endometrial Cancers|*Sequencing, RNA|Chemotherapy, Adjuvant|Antineoplastic Combined Chemotherapy Protocols|*Base Sequence|Neoplasm Recurrence, Local|*Whole Exome Sequencing|*Endometrium|*Biomarkers|Cohort Studies|PTP4A3 protein, human|Neoplasm Proteins|Protein Tyrosine Phosphatases 22 MICAL2 29738722 Curr. Biol. 2018 PMC6778685 10.1016/j.cub.2018.01.025 5 0 0 153 LIM Domain Proteins|Cytoskeletal Proteins|Actin|Actin Cytoskeleton|Adaptor Proteins, Signal Transducing|Redox|DNA-Binding Proteins|Signal Transduction 22 MICAL2 29483957 J Cancer 2018 PMC5820919 10.7150/jca.22355 3 70 0 153 *Epithelial-Mesenchymal Transition|*Tumor Promoters|*Cell Proliferation|Cell Movement|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|*Neoplastic Processes|Semaphorin|*Cell Transformation, Neoplastic 22 MIDN 29800848 Sci. Total Environ. 2018 10.1016/j.scitotenv.2018.05.159 0 0 0 245 Animals|*Zebrafish|*Larvae|fipronil|*Pyrazoles|Embryo, Nonmammalian|Toxicity Test, Acute|Insecticides|Water Pollutants, Chemical|*Gene Expression Profiling|*Microarray Analysis|Camptocormia|Spinal Curvatures|Muscular Atrophy, Spinal|Europe 23 MIDN 29311479 Biol. Pharm. Bull. 2018 10.1248/bpb.b17-00663 4 0 0 245 Humans|*Parkinson Disease|midnolin|*Nuclear Proteins|parkin protein|Ubiquitin-Protein Ligases|Synuclein|*Transcriptome Analysis|Mutation|Sequencing, RNA|mRNA 23 MIEN1 30286132 PLoS ONE 2018 PMC6171864 10.1371/journal.pone.0204976 3 3 0 102 *Clustered Regularly Interspaced Short Palindromic Repeats|Guide RNA|Neoplasm Proteins|Cell Movement|Intracellular Signaling Peptides and Proteins|Cell Line, Tumor|Gene Expression|Actin|Genome|Genomics 33 MIEN1 29339925 Onco Targets Ther 2018 PMC5744744 10.2147/OTT.S113359 5 20 0 102 *Epithelial-Mesenchymal Transition|Cell Migration|*Colon Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Neoplasm Proteins|Cell Line, Tumor|3' Untranslated Region|Cell Proliferation|Downregulation|Intracellular Signaling Peptides and Proteins|Signal Transduction|NF-kappa B 33 MIPEP 30031264 Environ Int 2018 10.1016/j.envint.2018.06.042 0 0 0 43 Female|Pregnancy|Humans|phthalic acid|*Phthalic Acids|Environmental Pollutants|Environmental Exposure|Environmental Monitoring|Brazil 29 MIR135B 30526325 Cell Cycle 2018 PMC6343719 10.1080/15384101.2018.1556063 0 4 0 0 *Exosomes|*Chondrocytes|TGFB1 protein, human|*Transforming Growth Factor beta1|Mesenchymal Stem Cells|Cell Proliferation|MicroRNAs|Cells, Cultured|Signal Transduction 26 MIR135B 30502323 Gastroenterology 2018 PMC6409191 10.1053/j.gastro.2018.11.052 9 2 0 0 Humans|Mice|Animals|*RNA, Micro|*Stomach Neoplasms|*Carcinogenesis|TFF1 protein, human|Trefoil Factor 1|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Stomach|Cell Line, Tumor|mRNA|Cell Movement|Up-Regulation|Drug Resistance, Neoplasm|Signal Transduction 26 MIR135B 30265426 Genes Chromosomes Cancer 2018 PMC6437779 10.1002/gcc.22686 4 0 0 0 *Adenoma|*Colon Cancer|Colonic Polyps|*Sequencing, RNA|Colon|*Whole Exome Sequencing|Proto-Oncogene Proteins B-raf|*Base Sequence|Hyperplasia|Biomarkers, Tumor|MicroRNAs 26 Mkx 30505649 Curr Mol Biol Rep 2018 PMC6261384 10.1007/s40610-018-0100-3 4 0 0 126 *Nucleus Pulposus|*Intervertebral Discs|Notochord 50 Mkx 30458056 J. Bone Miner. Res. 2018 PMC6535142 10.1002/jbmr.3630 2 0 0 126 Mice|Animals|*Achilles Tendon|*Hedgehog Proteins|*Ectopic Ossification|*Signal Transduction|Tendon Injury|Ossification 50 Mkx 30271862 Regen Ther 2018 PMC6149186 10.1016/j.reth.2017.12.001 4 5 0 126 *Anterior Cruciate Ligament|*Mesenchymal Stem Cells|Anterior Cruciate Ligament Reconstruction|Anterior Cruciate Ligament Injuries|Cell Differentiation|Osteogenesis|Cells, Cultured|*B Cells|Cell Separation|Fibroblasts|Collagen 50 Mkx 30262441 Vet Anaesth Analg 2018 10.1016/j.vaa.2018.07.005 0 0 0 126 Horses|Animals|Humans|*Xylazine|*Propofol|*Midazolam|*Ketamine|*Equidae|Anesthetics, Intravenous|Anesthesia, Intravenous|Hypnotics and Sedatives|Anesthesia Recovery Period|Heart Rate|Anesthesia, General|Blood Pressure|*Heart 50 Mkx 29926971 J. Orthop. Res. 2018 10.1002/jor.24076 1 0 0 126 Mice|Animals|*Achilles Tendon|*Transcriptome|*Progenitor Cells|Tendon Injuries|Extracellular Matrix|Cell Differentiation|Cell Movement 50 Mkx 29904202 Can. Vet. J. 2018 PMC5901856 0 0 0 126 Horses|Animals|Humans|*Xylazine|*Midazolam|*Ketamine|*Anesthesia, Intravenous|Anesthetics, Dissociative|*Anesthesia, General|Hypnotics and Sedatives|Anesthetics, Intravenous|Heart Rate|Anesthesia Recovery Period|Respiratory Rate|Blood Pressure 50 MLLT11 30277115 Leuk. Lymphoma 2018 10.1080/10428194.2018.1516876 2 0 0 143 Adult|Child|Humans|KMT2A protein, human|Myeloid-Lymphoid Leukemia Protein|*Leukemia, Myeloid, Acute|Histone-Lysine N-Methyltransferase|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Oncogene Proteins, Fusion|*Cohort Studies|Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Chinese|PCR, Multiplex|Genes, Regulator|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins 40 MLLT11 30154435 Cell Death Dis 2018 PMC6113287 10.1038/s41419-018-0900-7 0 24 0 143 Humans|*Imatinib Mesylate|*Cell Survival|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|Protein Kinase Inhibitors|K562 Cells|Drug Resistance, Neoplasm|Cell Line, Tumor|Apoptosis|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins 40 MLLT11 29858066 Mol Ther Nucleic Acids 2018 PMC5889700 10.1016/j.omtn.2018.03.003 4 21 0 143 Animals|Humans|*Urinary Bladder Neoplasms|*Down-Regulation|MicroRNAs|*Upregulation|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|mRNA|3' Untranslated Region|Cell Proliferation|Cell Movement|*Genes, Regulator|Cell Line, Tumor|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins|MIRN411 microRNA, human 40 MORC1 29982569 Genome Biol Evol 2018 PMC6048995 10.1093/gbe/evy136 5 4 0 59 Phylogeny|*Green Plants|Genes, Plant|Gene Expression Regulation, Plant|Rice|Arabidopsis|Gene Duplications|Plant Proteins|Multigene Family|Genome, Plant|Evolution, Molecular|Soy Bean|Amino Acid Sequence|*Biological Evolution 26 MORC1 29890506 J Psychiatr Res 2018 10.1016/j.jpsychires.2018.05.026 2 1 0 59 Humans|Adult|Male|Female|Young Adult|*Depression|Mouth Mucosa|DNA Methylation|Epigenesis, Genetic|Promoter Regions, Genetic|Depressive Disorder, Major|Stress, Life|*Biomarkers 26 MORC1 29577542 Plant Biotechnol. J. 2018 PMC6181210 10.1111/pbi.12924 3 12 0 59 *Hordeum|*Guide RNA|*CRISPR-Cas Systems|*Gene Editing|Plant Proteins|Disease Resistance|Plants, Genetically Modified|Arabidopsis|Plant Immunity|Genome, Plant|Gene Silencing|Transposable Elements|Mutations 26 MPZL2 30564267 Front Genet 2018 PMC6288178 10.3389/fgene.2018.00513 1 0 0 144 Humans|Animals|Rats|Female|Male|*Up-Regulation|Quantitative Trait Locus|Animals, Congenic|Rats, Inbred Strains|Chromosome Mapping|Alcohol Consumption|Genotype|Phenotype|Ethanol|*Transcriptional Activation|*Estrogens 22 MPZL2 29982980 Hum. Genet. 2018 PMC6478175 10.1007/s00439-018-1901-4 2 0 0 144 Humans|Mice|Animals|Nonsyndromic Deafness|*Deafness|Hearing Loss, Sensorineural|Genes, Recessive|Pedigree|Haplotype|Mutation|Genetic Linkage|Allele Frequency|Iran|Turkey 22 MPZL2 29961571 Am. J. Hum. Genet. 2018 PMC6037131 10.1016/j.ajhg.2018.05.011 2 0 0 144 Mice|Animals|*Myelin P0 Protein|*Hearing|Spiral Ganglion|Nonsyndromic Deafness|Deafness|Hair Cells, Auditory|Hearing Loss, Sensorineural|*Hearing Tests|Homozygote|Mutation 22 MRGPRD 30563864 Sci Signal 2018 PMC6411128 10.1126/scisignal.aal2171 2 0 0 47 Humans|Mice|Animals|*Irritable Bowel Syndrome|5-oxo-6,8,11,14-eicosatetraenoic acid|*Nociception|Arachidonic Acids|Constipation|*Receptors, G-Protein-Coupled|Colon|Sensory Neurons|Abdominal Pain|Ganglia, Spinal|Biopsies 50 MRGPRD 30532001 Nature 2018 PMC6461409 10.1038/s41586-018-0793-8 14 0 0 47 Humans|Mice|Animals|*Pain|Nociceptors|Neurons|Neural Pathways|*Adaptation, Psychological 50 MRGPRD 30339496 Am. J. Physiol. Heart Circ. Physiol. 2018 10.1152/ajpheart.00075.2018 8 0 0 47 Mice|Animals|alamandine|*Cardiomyopathy, Dilated|angiotensin I (1-7)|Angiotensin I|*Oligopeptides|Peptide Fragments|Renin-Angiotensin System|Receptors, G-Protein-Coupled|*Gene Deletion|Signal Transduction|Cardiomyocytes|Ventricular Remodeling, Left 50 MRGPRD 30225912 J. Comp. Neurol. 2018 PMC6283681 10.1002/cne.24533 1 0 0 47 Neurons, Afferent|Afferent Pathways|Skin|Spinal Cord Dorsal Horn|*Musculoskeletal Physiological Phenomena|*Nervous System Physiological Phenomena 50 MRGPRD 30148678 FASEB J. 2018 PMC6988841 10.1096/fj.201800615RR 6 1 0 47 Humans|Animals|*Pain, Neuropathic|Ganglia, Dorsal Root|Allodynia|Nociceptive Neurons|Signal Transduction|Neurons|Itching 50 MRGPRD 29998915 Circ. J. 2018 10.1253/circj.CJ-17-1381 3 0 0 47 Animals|Rats|alamandine|*Rats, Sprague-Dawley|*Oligopeptides|*Heart|Myocardial Reperfusion Injury|NPPA protein, human|Atrial Natriuretic Factor|*Protective Agents|Myocardial Ischemia|Antioxidants|angiotensin I (1-7)|Peptide Fragments|Apoptosis|Angiotensin I 50 MRGPRD 29864146 PLoS ONE 2018 PMC5986144 10.1371/journal.pone.0198601 8 3 0 47 Mice|Animals|Cre recombinase|*Calcitonin Gene-Related Peptide|*Sensory Neuron|Integrases|Dorsal Root Ganglion|Nociceptors|TRPV Cation Channels|NAV1.8 Voltage-Gated Sodium Channel|Capsaicine|Transgenic Mouse|TRPV1 protein, mouse 50 MRGPRD 29752563 Amino Acids 2018 PMC6060955 10.1007/s00726-018-2583-x 8 14 0 47 Rats|Animals|alamandine|*Hypertension|*Cardiac Hypertrophy|*Oligopeptides|Antihypertensive Agents|Spontaneously Hypertensive Rats|Blood Pressure|Angiotensin II|Cardiomyocyte|NPPA protein, human|Atrial Natriuretic Factor|Signal Transduction|Protein Kinase A|Left Ventricle 50 MRGPRD 29443552 Am. J. Physiol., Cell Physiol. 2018 10.1152/ajpcell.00153.2017 7 4 0 47 Animals|Mice|*Angiotensin II|*Myocytes, Cardiac|alamandine|*Nitric Oxide|*AMP-Activated Protein Kinases|*Mice, Inbred C57BL|*Oligopeptides|Angiotensin I|Renin-Angiotensin System|Cardiomegaly|Signal Transduction|Receptors, G-Protein-Coupled|Antihypertensive Agents|Peptide Fragments|Vasodilation|*Peptide Hormones|Protein Binding|Cells, Cultured 50 MRGPRD 29425508 Cell Rep 2018 PMC5832359 10.1016/j.celrep.2018.01.041 20 7 0 47 Mice|Animals|*Osteocytes|Beta-Aminoisobutyric Acid, Urinary Excretion of|*Aminoisobutyric Acids|3-aminoisobutyric acid|*Amino Acid Metabolism, Inborn Errors|Insulin Resistance|*Muscle|Signal Transduction|AMP-Activated Protein Kinases|Reactive Oxygen Species 50 MRO 30515507 Phys Chem Chem Phys 2018 10.1039/c8cp05654d 0 0 0 123 *Molecular Dynamics Simulation|*Iron|Crystallization|Phase Transition|Thermodynamics|Models, Chemical|Temperature|*Physical Phenomena 186 MRO 30479306 Infect Dis Health 2018 10.1016/j.idh.2017.10.002 0 0 0 123 Humans|*Methicillin-Resistant Staphylococcus aureus|*Anti-Bacterial Agents|*Methicillin|*Patient Discharge|*Drug Resistance, Bacterial|Infection Control|Healthcare Associated Infection|Staphylococcal Infections|Hospitals|Screening|Australia 186 MRO 30324441 Methods Mol. Biol. 2018 10.1007/978-1-4939-8669-9_9 1 0 0 123 Mice|Animals|*Organoids|*Mouse Embryonic Stem Cells|*Retina|Retinal Cone|Human Embryonic Stem Cells|Pluripotent Stem Cells|Cell Differentiation 186 MSMB 30593751 Exp. Oncol. 2018 0 0 0 106 119 MSMB 30073682 Prostate 2018 10.1002/pros.23698 2 0 0 106 119 MTX3 29975729 PLoS ONE 2018 PMC6033413 10.1371/journal.pone.0199094 1 5 0 133 Humans|*Hepatitis B Surface Antigens|*Hepatitis B, Chronic|Genome-Wide Association Study|Hepatitis B virus|DNA, Viral|Antiviral Agents|Viral Load|Genotype|Polymorphism, Single Nucleotide 21 MXD1 30420889 Stem Cells Int 2018 PMC6215545 10.1155/2018/3286949 1 30 0 873 *Hematopoietic Stem Cells|FLT3 protein, human|*fms-Like Tyrosine Kinase 3|*Myeloproliferative Disorders|*Signal Transduction|Leukemia, Myeloid, Acute|Mutations|Cell Proliferation 172 MXD1 30419548 Leuk. Res. 2018 10.1016/j.leukres.2018.10.012 0 3 0 873 Humans|*Imatinib Mesylate|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|K562 Cells|Genes, abl|Drug Resistance, Neoplasm|Protein Kinase Inhibitors|Antineoplastic Agents|Gene Expression Regulation, Leukemic|Apoptosis|Cell Line, Tumor|MXD1 protein, human|Repressor Proteins|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors 172 MXD1 29762675 Endocrinology 2018 PMC6692881 10.1210/en.2018-00172 2 6 0 873 Animals|*Xenopus laevis|*Retinoid X Receptors|*Tadpoles|*Ligands|*Thyroid Hormones|Thyroid Hormone Receptors|Metamorphosis, Biological|*Signal Transduction|Receptors, Retinoic Acid|Triiodothyronine|tributyltin|Trialkyltin Compounds|Gene Expression Regulation, Developmental|Regulatory Sequences, Nucleic Acid|RNA, Messenger 172 MXD1 29383100 Oncotarget 2018 PMC5777712 10.18632/oncotarget.21457 4 17 0 873 Mice|Animals|*Sirtuin 1|Melanoma, Cutaneous Malignant|*Malignant Melanoma|*Skin Neoplasms|Melanocytes|*Disease Progression|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|Cell Line, Tumor|Cell Transformation, Neoplastic|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Repressor Proteins|Chromatin|Protein Binding|Sirt1 protein, mouse 172 MXD1 29356724 Am. J. Surg. Pathol. 2018 PMC5893407 10.1097/PAS.0000000000001021 13 1 0 873 Humans|Child, Preschool|Child|Adolescent|Young Adult|Adult|Middle Aged|Aged|*Transcription Factors|Nuclear Proteins|In Situ Hybridization, Fluorescence|*Gene Fusions|Soft Tissue Neoplasms|Gene Rearrangement|Sarcoma|Oncogene Proteins, Fusion|Biomarkers, Tumor|Carcinoma|*Genes, Regulator|Epithelioid Cells|Sequencing, Next-Generation|MXD1 protein, human|Repressor Proteins|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|BRD4 protein, human 172 Mxi1 30413886 J. Bone Miner. Metab. 2018 10.1007/s00774-018-0963-7 1 0 0 261 *Computational Biology|*Osteocytes|Protein Interaction Maps|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Databases, Genetic|Software|Protein Interaction Mapping|Gene Expression Regulation, Neoplastic|Transcriptome|Signal Transduction|Biomarkers, Tumor 182 Mxi1 30123320 J Biol Eng 2018 PMC6090965 10.1186/s13036-018-0101-z 2 2 0 261 *CRISPR|*Saccharomyces cerevisiae|gRNA|CRISPR-Cas System|Gene Editing|*Yeast, Dried|Endonucleases|Genetic Engineering|DNA|*Biosensors 182 Mxi1 30118760 Cell. Signal. 2018 10.1016/j.cellsig.2018.08.009 3 8 0 261 *Endothelial Cells|*Up-Regulation|MXI1 protein, human|*Basic Helix-Loop-Helix Transcription Factors|*Tumor Suppressor Proteins|siRNA|Reactive Oxygen Species|Cell Hypoxia|Signal Transduction|Apoptosis|Forkhead Box Protein O3|*Hypoxia|Forkhead Transcription Factors|Transfection|*Cell Death 182 Mxi1 29917323 Biotechnol J 2018 10.1002/biot.201700598 4 0 0 261 *Gene Editing|*Clustered Regularly Interspaced Short Palindromic Repeats|CRISPR-Cas Systems|DNA End-Joining Repair|Genetic Engineering|Homologous Recombination|DNA Breaks, Double-Stranded|*Gene Expression|*Saccharomycetales 182 Mxi1 29676954 Physiol. Genomics 2018 10.1152/physiolgenomics.00022.2018 5 0 0 261 Cattle|Animals|*Genome-Wide Association Study|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Phenotype|Genotype|*Organ Size|Meat 182 Mxi1 29507620 Theranostics 2018 PMC5835936 10.7150/thno.22552 5 52 0 261 182 Mxi1 29453220 J. Clin. Pathol. 2018 10.1136/jclinpath-2017-204961 3 0 0 261 *Multiple Myeloma|Gene Fusion|Translocation, Genetic|High-Throughput Nucleotide Sequencing|In Situ Hybridization, Fluorescence|Gene Expression Profiling 182 MXRA5 30414097 J. Neurooncol. 2018 10.1007/s11060-018-03029-3 6 1 0 21 Humans|*Glioblastoma|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Prognosis|Biomarkers, Tumor|Cell Proliferation|RNA, Messenger|Neural Stem Cell|Mutation 23 MXRA5 29877573 Int. J. Dev. Biol. 2018 10.1387/ijdb.170225ac 0 0 0 21 Animals|Chick Embryo|*Limb|Mesenchyme|Limb Buds|In Situ Hybridization|Gene Expression Regulation, Developmental|*Torso|Extracellular Matrix|RNA, Messenger|*Birds 23 MXRA5 29453465 Int J Obes (Lond) 2018 10.1038/s41366-018-0018-0 3 0 0 21 *Adipokines|*Insulin Resistance|*Adipose Tissue|Adipose Tissue, White|Obesity|Adipose Tissue, Subcutaneous|*Biomarkers 23 MYCL 30404920 J. Biol. Chem. 2018 PMC6290138 10.1074/jbc.TM118.003336 6 0 0 170 Ornithine Decarboxylase Inhibitors|Eflornithine|N-Myc Proto-Oncogene Protein|Ornithine Decarboxylase|Neuroblastoma|Polyamines|Nuclear Proteins|Cell Line, Tumor 95 MYCL 30324095 Res Rep Urol 2018 PMC6174915 10.2147/RRU.S173377 0 10 0 170 Humans|Male|CAV1 protein, human|*Caveolin 1|*Prostatic Neoplasms, Castration-Resistant|CAV2 protein, human|Caveolin-2|*Cell Motility|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Membrane Proteins|Disease Progression|Signal Transduction 95 MYCL 30224629 Nat Commun 2018 PMC6141466 10.1038/s41467-018-06162-9 9 0 0 170 Humans|*Small Cell Lung Carcinoma|*Wnt Signaling Pathway|Neoplasm Recurrence, Local|Lung Neoplasms|Drug Resistance, Neoplasm|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Gene Knockdown Techniques|multidrug resistance-associated protein 1|Multidrug Resistance-Associated Proteins|*Relapse 95 MYCL 30158974 Int J Endocrinol 2018 PMC6109482 10.1155/2018/5406128 0 0 0 170 Female|Humans|*Polycystic Ovary Syndrome|Glucose Tolerance Test|Insulin Resistance|*Adipose Tissue|Blood Glucose|Body Mass Index|Insulin|*Carbohydrate Metabolism|Obesity|Testosterone 95 MYCL 29343221 BMC Med. Genet. 2018 PMC5772742 10.1186/s12881-018-0526-8 0 0 0 170 Child|Humans|*Medulloblastoma|Cerebellar Neoplasms|Cranial Irradiation|Chemotherapy, Adjuvant|Vincristine|Disease-Free Survival|Cisplatin|Antineoplastic Combined Chemotherapy Protocols 95 MYH15 30505812 Adv Biomed Res 2018 PMC6233028 10.4103/abr.abr_80_18 1 0 0 40 *Whole Exome Sequencing|*Computational Biology|Exome|Pedigree|*Hearing Loss, Sensorineural|Sequence Analysis, DNA|DNA Copy Number Variations|Phenotype|Hearing Loss|Mutation|*Deafness|Polymorphism, Single Nucleotide 24 MYH15 29326596 Front Physiol 2018 PMC5736872 10.3389/fphys.2017.01049 3 3 0 40 Sheep|Female|Animals|*RNA, Long Noncoding|*mRNA|*miRNA|*Fecundity|*Breeding|Sheep, Domestic|Networks, Gene|Gene Expression Profiling|Ovaries|Transcriptome|Genotype|Genome 24 MYO18B 30581023 Curr. Biol. 2018 PMC6347125 10.1016/j.cub.2018.11.045 5 0 0 35 *Actomyosin|*Myosin B|*Myosin II|*Filaments, Actin|Myosin|Fibers, Stress|*Muscle Contraction|Morphogenesis|*Cytoskeletal Proteins|Mechanical Phenomena|Cell Movement|Cell Adhesion 42 MYO18B 30575306 Cancer Med 2018 PMC6346238 10.1002/cam4.1917 3 0 0 35 Child|Humans|*Genes, Homeobox|*DNA Methylation|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|CpG Islands|*Gene Expression|*Transcriptome Analysis|Phenotype|Prognosis|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Oncogene Proteins, Fusion|*DNA-Binding Proteins|*Biochemical Phenomena|T-Lymphocytes|TAL1 protein, human|T-Cell Acute Lymphocytic Leukemia Protein 1|HOXA10 protein, human|Homeobox A10 Proteins 42 MYO18B 30390677 Diagn Pathol 2018 PMC6215340 10.1186/s13000-018-0763-3 0 12 0 35 *Carcinoma, Hepatocellular|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Liver Neoplasms|*Signal Transduction|MTOR protein, human|*TOR Serine-Threonine Kinases|Phosphatidylinositol 3-Kinase|Cell Movement|Cell Proliferation|Neoplasm Invasiveness|PTEN Phosphohydrolase|Hep G2 Cells|Gene Expression Regulation, Neoplastic|Apoptosis|Phosphorylation|Cell Line, Tumor|*Disease Progression 42 myo1f 29910823 Front Genet 2018 PMC5992410 10.3389/fgene.2018.00183 3 0 0 128 *Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Gene Expression Profiling|Transcriptome|Prognosis|Gene Expression Regulation, Neoplastic|*Disease Progression 25 myo1f 29672841 Int. 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Cancer 2018 10.1002/ijc.31548 5 1 0 128 *Thyroid Cancer|Familial Nonmedullary Thyroid Cancer|Genetic Linkage|Adenoma, Oxyphilic|Pedigree|Thyroid Gland|Genetic Predisposition to Disease|Germ-Line Mutation|Mutation|Genotype|*Mitochondria|Cell Proliferation 25 myo1f 29487067 Blood 2018 10.1182/blood-2017-10-811851 11 0 0 128 Mice|Animals|*Neutrophils|*Myosin B|Neutrophil Infiltration|*Cell Movement|*Inflammation|Mice, Knockout|Peritonitis|Myosin I 25 MYO5C 30496538 Genome Biol Evol 2018 PMC6372264 10.1093/gbe/evy258 0 0 0 604 Animals|MYO5A protein, human|*Myosin Type V|Phylogeny|*Genes, Duplicate|Gene Duplication|Evolution, Molecular|Synteny|Genome|*Myosin Heavy Chains|Sequence Alignment|*Biological Evolution|Vertebrates|Fishes|Genomics 22 MYO5C 29883837 J Thorac Oncol 2018 10.1016/j.jtho.2018.05.026 7 0 0 604 Humans|*Carcinoma, Non-Small-Cell Lung|*Protein-Tyrosine Kinases|*Lung Neoplasms|*Proto-Oncogene Proteins|Crizotinib|Anaplastic Lymphoma Kinase|Gene Rearrangement|Receptor Protein-Tyrosine Kinases|Adenocarcinoma|Pyrazoles|Brain Neoplasms|Pyridines|Treatment Outcome|ROS1 protein, human 22 MYO5C 29325019 Hum. Mol. Genet. 2018 PMC5886112 10.1093/hmg/ddy006 3 11 0 604 Epigenesis, Genetic|CpG Islands|DNA Methylation|Epigenomics|*Phenotypes|Genome-Wide Association Study|Basic Helix-Loop-Helix Transcription Factors|Repressor Proteins|Smoking|Tobacco Smoking|Metabolomics|Lipids|Obesity|Qatar 22 MZB1 30257949 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6187189 10.1073/pnas.1809739115 7 41 0 35 PRDM1 protein, human|*Positive Regulatory Domain I-Binding Factor 1|*Lymphocyte Activation|B Cells|*Integrins|Plasma Cells|Cell Differentiation|*Hematopoiesis|Gene Expression 25 MZB1 30038789 Mult Scler J Exp Transl Clin 2018 PMC6050818 10.1177/2055217318787826 0 4 0 35 *B-DNA|*DNA Methylation|Dimethylfumarate|Multiple Sclerosis, Relapsing-Remitting|Immunosuppressive Agents|Fumarates|Multiple Sclerosis|Administration, Oral 25 MZB1 29921943 Sci Rep 2018 PMC6008462 10.1038/s41598-018-27627-3 1 1 0 35 Humans|*Transcriptome|*Gingiva|Periodontium|*Gene Expression Profiling|*Microarray Analysis|Chronic Periodontitis|Sequencing, RNA|Immunohistochemistry|Real-Time Polymerase Chain Reaction 25 MZB1 29382365 Arthritis Res. Ther. 2018 PMC5791339 10.1186/s13075-018-1511-5 2 8 0 35 *Proteomics|*Lupus Erythematosus, Systemic|*B Cells|Autoantibodies|Autoimmune Disease|*Lymphoid Tissue|Cytokines|Biomarkers|Lymph Nodes 25 MZF1 30534177 Evid Based Complement Alternat Med 2018 PMC6252237 10.1155/2018/6746412 2 4 0 334 Humans|haematoside synthetase|*Curcumin|*HCT116 Cells|*Sialyltransferases|*Downregulation|*Autophagy|Transcriptional Activation|Gene Expression Regulation, Enzymologic|*Gene Expression|*Colonic Neoplasms|Promoter Regions, Genetic|RNA, Messenger|Colon 165 NCAM2 30530861 J. Neurosci. 2018 PMC6382982 10.1523/JNEUROSCI.3594-17.2018 4 0 0 77 Male|Female|Mice|Animals|*Olfactory Epithelium|Sensory Neurons, Olfactory|Cell Differentiation|Neural Stem Cells|Neurogenesis|Nerve Tissue Proteins|Regeneration|Ncam2 protein, mouse|Neural Cell Adhesion Molecules 71 NCAM2 30391830 Domest. Anim. Endocrinol. 2018 10.1016/j.domaniend.2018.09.003 0 0 0 77 Cattle|Animals|*Transcriptome|*Pituitary Glands|*Pituitary Diseases|Transcriptome Profiling|Sequence Analysis, RNA|High-Throughput RNA Sequencing|Breeding|Genomes|Gene Ontology|Gene Annotations|Pituitary Hormones|RNA, Messenger 71 NCAM2 29895898 Sci Rep 2018 PMC5997747 10.1038/s41598-018-27089-7 2 20 0 77 *Fibroblast Growth Factor Receptor|*Fibronectins|Scattering, Small Angle|X-Ray Diffraction|NCAM2 protein, human|*Neural Cell Adhesion Molecule L1|*Fibronectin Type III Domains|Neural Cell Adhesion Molecules|Phosphorylation|Neurites|Neurons|Cells, Cultured|Signal Transduction|Peptides|Cell Line|Neurite Outgrowth 71 NCAM2 29522129 Cereb. Cortex 2018 10.1093/cercor/bhy041 3 0 0 77 Animals|Mice|Humans|*Calcium|Synapses|Dendrites|Neurons|NCAM2 protein, human|Neural Cell Adhesion Molecule L1|Hippocampus|Ncam2 protein, mouse|Neural Cell Adhesion Molecules 71 NCAM2 29367452 G3 (Bethesda) 2018 PMC5844316 10.1534/g3.118.200019 4 5 0 77 Animals|Humans|Caenorhabditis elegans Proteins|Caenorhabditis elegans|Animals, Genetically Modified|Phenotypes|Down Syndrome|*Human Chromosome|Mutations|Disease Models, Animal 71 ncln 30544572 Molecules 2018 PMC6321123 10.3390/molecules23123237 1 0 0 65 *Water|Solutions|Spectrophotometry, Infrared|Spectrum Analysis, Raman|Models, Molecular|Vibration|*Physical Phenomena 21 ncln 30023322 Adv Pharm Bull 2018 PMC6046415 10.15171/apb.2018.025 2 6 0 65 21 NEFH 30567555 BMC Med Genomics 2018 PMC6299999 10.1186/s12920-018-0446-7 1 0 0 382 Humans|*Intellectual Disability|Comparative Genomic Hybridization|*Genes, X-Linked|Exome|Pedigree|Fragile X Syndrome|Fragile X Mental Retardation Protein|Chromosome Mapping|Whole Exome Sequencing|Genetic Association Studies|Massively Parallel Sequencing|Phenotype|*Variable Tandem Repeat|Tandem Repeat|Mutation 89 NEIL3 30591675 Int J Mol Sci 2018 PMC6337670 10.3390/ijms20010097 3 0 0 86 *Colorectal Cancer|Single Nucleotide Polymorphisms|DNA Repair|Genetic Predisposition to Disease|DNA-Binding Proteins|Nuclear Proteins|Genotype|*Colonic Neoplasms|Czech Republic|Austria 87 NEIL3 30542483 Exp Ther Med 2018 PMC6257675 10.3892/etm.2018.6874 1 0 0 86 Humans|Stroke|Single Nucleotide Polymorphisms|Brain Ischemia|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|Odds Ratio|Case-Control Studies|Risk Factors 87 NETO2 30265975 Transl Oncol 2018 PMC6161410 10.1016/j.tranon.2018.09.003 2 2 0 171 Humans|Male|*Prostate Cancer|Genetic Heterogeneity|Biomarkers, Tumor|PTEN Phosphohydrolase|Mutation|Disease Progression|Phenotypes 53 NETO2 30186694 PeerJ 2018 PMC6120446 10.7717/peerj.5527 0 11 0 171 Adult|Humans|*Transcriptome|*Cells, Erythroid|Erythroid Precursor Cells|Erythropoiesis|Cell Differentiation|Cells, Cultured|Gene Expression Profiling|Fetal Blood|Liver 53 NETO2 29989576 Mol. Biol. (Mosk.) 2018 10.7868/S0026898418030072 1 0 0 171 *Carcinoma, Renal Cell|Kidney Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|mRNA|Upregulation|*Gene Expression|3'-(1-butylphosphoryl)adenosine|*Complement Factor B|Transcription Factors 53 NETO2 29629573 Cartilage 2018 PMC7097986 10.1177/1947603518764260 2 0 0 171 *Intervertebral Disk|Anulus Fibrosus|Nucleus Pulposus|*Biomarkers|Gene Expression Profiling 53 NETO2 29297384 BMC Genet. 2018 PMC5751543 10.1186/s12863-017-0581-8 5 3 0 171 *Up-Regulation|*Colorectal Cancer|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|MicroRNAs|*Colonic Neoplasms|*Transcriptional Activation|Cell Movement|Cell Line, Tumor|Membrane Proteins 53 Neurod2 30323019 J. Med. Genet. 2018 10.1136/jmedgenet-2018-105322 2 0 0 154 Infantile Epileptic-Dyskinetic Encephalopathy|*Spasms, Infantile|Mutation|Phenotype|Sequencing, Next-Generation 116 Neurod2 30224541 Mol. Cancer Res. 2018 PMC6318027 10.1158/1541-7786.MCR-18-0485 0 9 0 154 Humans|Child|*Medulloblastoma|*Hedgehog Proteins|*Tumor Suppressor Protein p53|Cerebellar Neoplasms|Signal Transduction|Cell Proliferation|Neurons|Phosphoric Monoester Hydrolases 116 Neurod2 30108155 J. Lipid Res. 2018 PMC6168314 10.1194/jlr.P080218 0 0 0 154 Humans|*Genome-Wide Association Study|*Arabs|*Hypertriglyceridemia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Recessive Gene|Phenotype|European Continental Ancestry Group|Lipids|Kuwait 116 Neurod2 29997476 Front Mol Neurosci 2018 PMC6028693 10.3389/fnmol.2018.00219 0 3 0 154 Rats|Animals|*Trigeminal Ganglion|*Leukocytes, Mononuclear|*Orofacial Pain|Freund's Adjuvant|Trigeminal Caudal Nucleus|Rats, Sprague-Dawley|Inflammation|*Cell Nucleus|*Leukocytes|*Mononuclear Phagocyte System 116 Neurod2 29494346 J. Clin. Invest. 2018 PMC5919825 10.1172/JCI96165 1 1 0 154 Mice|Animals|protein kinase N|AKT1 protein, human|*Protein Kinase B|Purkinje Cell|Protein Kinase C|Synapse|Cerebellum|Long-Term Synaptic Depression|Axons|Presynaptic Terminals|Receptors, Glutamate|Neuronal Plasticity|Nerve Fibers|Neurons|Mice, Knockout|*Neurogenesis 116 NEUROD4 30513512 Cell. Physiol. Biochem. 2018 10.1159/000495717 5 0 0 53 *miRNA|*Injury, Spinal Cord|*Inflammation|Spinal Cord|Up-Regulation 59 NEUROD4 30307165 J. Mol. Endocrinol. 2018 10.1530/JME-18-0090 0 0 0 53 Mice|Animals|ASCL1 protein, human|*Basic Helix-Loop-Helix Transcription Factors|NeuroD protein|*Nerve Tissue Proteins|Transcription Factors|Helix-Loop-Helix Motifs|Cell Differentiation|*Pituitary Gland|*Pituitary Diseases|Progenitor Cells|Neurons|Gene Expression|Neurog2 protein, mouse 59 NEUROD4 30073347 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24236 1 0 0 53 *Organogenesis|Eye Proteins|Microphthalmia|Homeodomain Proteins|Coloboma|Anophthalmia|Gene Expression Regulation, Developmental|Eye Abnormalities|Retina|Morphogenesis|Intracellular Signaling Peptides and Proteins|Cell Proliferation 59 NEUROD4 29687839 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201804_14709 4 1 0 53 *Injury, Spinal Cord|MIRN137 microRNA, human|*MicroRNAs|*Inflammation|*Oxidative Stress|Recovery of Function 59 NEUROD6 30592042 J. Comp. Neurol. 2018 10.1002/cne.24621 0 0 0 73 Animals|Mice|*Olfactory Bulb|*Sensory Deprivation|*Neurons|Neurogenesis|Neural Stem Cells|Interneurons|Brain|Neurod6 protein, mouse|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 84 NEUROD6 30201687 Development 2018 PMC6198467 10.1242/dev.157719 1 1 0 73 Neurons|Basic Helix-Loop-Helix Transcription Factors|Neurogenesis|Neural Stem Cells|Neocortex|Nerve Tissue Proteins|Cell Differentiation|Gene Expression Regulation, Developmental|Cells, Glial|Repressor Proteins 84 NEUROD6 30135866 eNeuro 2018 PMC6104179 10.1523/ENEURO.0152-18.2018 8 0 0 73 Animals|Mice|Neurons, Dopamine|Ventral Tegmental Area|Dopamine|Mesencephalon|Nucleus Accumbens|Neural Pathways|Glutamic Acid|Nerve Tissue Proteins|Brain 84 NEUROD6 29803225 J Neuroinflammation 2018 PMC5970532 10.1186/s12974-018-1179-4 3 16 0 73 Mice|Animals|*Dopamine|*1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|*Indometacin|*Hippocampus|Neurogenesis|Substantia Nigra|MPTP Poisoning|Dopaminergic Neurons|Tyrosine 3-Monooxygenase|Mice, Inbred C57BL|Disease Models, Animal|Learning, Spatial|Nestin|Parkinson Disease|Bromodeoxyuridine|Anti-Inflammatory Agents 84 NEUROD6 29502200 Acta Neuropathol. 2018 PMC5955788 10.1007/s00401-018-1829-8 19 1 0 73 *Neurons|*Cornu Ammonis|alpha-Synuclein|Protein Aggregation, Pathological|Parkinson Disease|Neurodegenerative Disorders|Nerve Degeneration 84 NEUROD6 29500414 Cell Death Dis 2018 PMC5834638 10.1038/s41419-018-0396-1 4 23 0 73 Rats|Animals|*Organelle Biogenesis|Epigenesis, Genetic|*Cell Differentiation|Neural Stem Cells|Neurogenesis|Embryonic Stem Cells|Neurons|*Cell Respiration|Mitochondria|bHLH Transcription Factors|PC12 Cells|Chromatin|Acetylation|CREBBP protein, human|CREB-Binding Protein|Histones|Cell Survival|DNA, Mitochondrial 84 NEUROD6 29351579 Cereb. Cortex 2018 10.1093/cercor/bhx360 5 0 0 73 *Methyl-CpG-Binding Protein 2|*Cell Differentiation|Neurons|Rett Syndrome|Neurogenesis|*Embryonic Development|Gene Expression Regulation, Developmental|Cerebral Cortex|Embryo, Mammalian|Nerve Tissue Proteins|Cells, Cultured 84 Nfkbil1 30555476 Front Immunol 2018 PMC6283264 10.3389/fimmu.2018.02792 6 1 0 46 Mice|Animals|*miRNA|*Toll-Like Receptor|Leishmaniasis|Leishmania|Macrophage Activation|Macrophages|Nitric Oxide Synthase Type II|Tumor Necrosis Factor-alpha|Mice, Knockout 67 Nfkbil1 30176756 Innate Immun 2018 PMC6830876 10.1177/1753425918796207 1 0 0 46 Humans|*Haplotypes|*Periodontitis|MMP8 protein, human|Matrix Metalloproteinase 8|Porphyromonas gingivalis|Lymphotoxin|Periodontal Pockets|*Biomarkers|Saliva|Genetic Predisposition to Disease|Periodontal Index|Polymorphism, Genetic|Interleukin-1beta|Odds Ratio|Inflammation|Logistic Models 67 NFX1 30503395 Gene 2018 10.1016/j.gene.2018.11.075 3 0 0 98 Humans|*RNA, Long Noncoding|*Zinc|Carcinogenesis|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|Cell Line, Tumor|Small Nucleolar RNA|Signal Transduction|Apoptosis|Zinc Finger 45 NFX1 30288832 Cell Prolif. 2018 PMC6430496 10.1111/cpr.12513 7 0 0 98 Humans|*RNA, Long Noncoding|*Oncogenesis|*Oncogenes|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Gastric Cancer|Signal Transduction|Disease Progression 45 NFX1 29618337 BMC Genomics 2018 PMC5885410 10.1186/s12864-018-4632-y 5 3 0 98 Male|Female|Sheep|Animals|*Transcriptome|*Essential Oils|*Networks, Gene|Sequencing, RNA|*Sheep, Domestic|*Liver|Animal Feed|Diet|High-Throughput RNA Sequencing|Digestion|Gene Expression Profiling|Gene Expression Regulation|Dietary Supplements|Nutrigenomics|*Muscle|Antioxidants 45 NINJ1 30510259 Sci Rep 2018 PMC6277454 10.1038/s41598-018-35997-x 4 1 0 93 Humans|Mice|Animals|*Alveolar Epithelial Cells|*Pulmonary Fibrosis|Bleomycin|*Macrophages|Pulmonary Alveoli|Epithelial Cells|Cells, Cultured|Nerve Growth Factors|Cell Adhesion Molecules, Neuronal|Upregulation|NINJ1 protein, human|Ninj1 protein, mouse 71 NINJ1 30354207 Arterioscler. Thromb. Vasc. Biol. 2018 PMC6166707 10.1161/ATVBAHA.118.311375 2 3 0 93 Mice|Animals|*Pericytes|Endothelial Cells|*Ischemia|Neovascularization, Physiologic|Hindlimb|Mice, Inbred C57BL|Regional Blood Flow|Muscle, Skeletal|Laser-Doppler Flowmetry|*Peripheral Vascular Diseases|Cells, Cultured|Disease Models, Animal|Ninj1 protein, mouse|Nerve Growth Factors|Cell Adhesion Molecules, Neuronal 71 NINJ1 30326781 Reprod Sci 2018 10.1177/1933719118806395 0 1 0 93 71 NINJ1 29500959 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.01.116 0 4 0 93 71 NLRP5 30218098 Eur. J. Hum. Genet. 2018 PMC6303262 10.1038/s41431-018-0269-1 3 1 0 64 Humans|Female|*Silver-Russell Syndrome|*Maternal Inheritance|*Mothers|*DNA Methylation|IGF2 protein, human|IGF-2|Genomic Imprinting|Beckwith-Wiedemann Syndrome|Fetal Growth Retardation|RNA, Long Noncoding|Mutation 65 NLRP5 30002204 Mol. Cell Proteomics 2018 PMC6166679 10.1074/mcp.RA118.000556 3 0 0 64 Pregnancy|Female|Animals|*Buffaloes|*Proteome|*Parthenogenesis|*Oocyte|Blastocyst|*Proteomics|Oogenesis|Morula|Embryo, Mammalian|Embryonic Development|Fertilization in Vitro|*Protein Processing, Post-Translational|mRNA|*Bison|Gene Expression Regulation, Developmental 65 NLRP5 29928061 PLoS ONE 2018 PMC6013205 10.1371/journal.pone.0199350 3 3 0 64 Humans|Genome-Wide Association Study|*NOD-like Receptors|*Colorectal Cancer|Single Nucleotide Polymorphisms|*Colon Cancer|Genetic Predisposition to Disease|Rectum|Colon|Case-Control Studies|Cohort Studies|Risk Factors|Germany|Scotland 65 NLRP5 29574422 J. Med. Genet. 2018 PMC6047157 10.1136/jmedgenet-2017-105190 20 4 0 64 Animals|Genomic Imprinting|Silver-Russell Syndrome|Beckwith-Wiedemann Syndrome|DNA Methylation 65 NNAT 30565863 J Diabetes Investig 2018 PMC6497585 10.1111/jdi.12993 0 1 0 165 *Glucose|Nerve Tissue Proteins|*Pancreas|Membrane Proteins|Endoplasmic Reticulum Stress 168 NNAT 30530915 Aging (Albany NY) 2018 PMC6326688 10.18632/aging.101680 5 1 0 165 Swine|Animals|*Melatonin|*Oocytes|In Vitro Oocyte Maturation Techniques|*Epigenesis, Genetic|Embryonic Development|DNA Methylation|Reactive Oxygen Species 168 NNAT 30302742 J Cardiovasc Transl Res 2018 10.1007/s12265-018-9830-0 2 0 0 165 Male|Animals|Mice|*RNA, Long Noncoding|*Insulin Resistance|*C57BL Mice|*Vascular System Injuries|mRNA|Diet, High-Fat|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Signal Transduction|Transcriptome|Aorta|Biomarkers|*Exercise Training 168 NNAT 30279096 Mol Metab 2018 PMC6308027 10.1016/j.molmet.2018.09.001 1 2 0 165 Humans|Adult|Child|Mice|Animals|Adolescent|*Mice, Inbred C57BL|type I signal peptidase|Membrane Proteins|*Obesity|Nerve Tissue Proteins|Genomic Imprinting|Leptin|Adipose Tissue, White|preproinsulin|Insulin|Insulin Secretion|Gene Expression Profiling|Diet|Insulin-Secreting Cells|Mice, Knockout|Phenotypes|Serine Endopeptidases 168 NNAT 30239726 Hum. Mol. Genet. 2018 PMC6337702 10.1093/hmg/ddy321 9 0 0 165 Humans|Male|Mice|Child|Animals|Female|Pregnancy|*Epigenome|Prospective Studies|Assisted Reproductive Technologies|Fertilization in Vitro|Intracytoplasmic Sperm Injection|*Placenta|Genomic Imprinting|Ovulation Induction|Pregnancy, Multiple|Infertility, Male|DNA Methylation|Epigenesis, Genetic|*Reproduction|Epigenetic|Fertilization|Embryo, Mammalian|BLCAP protein, human|Neoplasm Proteins 168 NNAT 29864031 J. Clin. Invest. 2018 PMC6063487 10.1172/JCI120115 6 18 0 165 Humans|Mice|Animals|*Insulin-Secreting Cells|Insulin Secretion|Nerve Tissue Proteins|*Pancreas|Insulin|Membrane Proteins|Glucose|Obesity|Endoplasmic Reticulum|Body Weight|Mice, Knockout|Gene Expression Profiling|Homeostasis 168 NNAT 29722939 Zhonghua Nan Ke Xue 2018 0 1 0 165 Male|Mice|Animals|*DNA Methylation|*Imprinting, Genetic|*Spermatozoa|*Obesity|Insulin-Like Growth Factor II|*Genome|*DNA|RNA, Long Noncoding 168 NNAT 29492305 Environ Epigenet 2018 PMC5804543 10.1093/eep/dvx003 10 3 0 165 Male|Humans|*DNA Methylation|*Flame Retardants|Genomic Imprinting|*Sperm|Insulin-Like Growth Factor II|RNA, Long Noncoding|triphenyl phosphate|Organophosphates|Sequence Analysis, DNA|Obesity|North Carolina 168 NOBOX 30333505 Sci Rep 2018 PMC6193033 10.1038/s41598-018-33575-9 3 1 0 47 Pregnancy|Female|Adult|Humans|Rats|Animals|*Mesenchymal Stem Cells|*Ovary|*Cultured Cell|Mesenchymal Stem Cell Transplantation|Spheroid, Cellular|Cell Culture Techniques|Cell Line|Placenta|NANOS3 protein, human|RNA-Binding Proteins 103 NOBOX 30154285 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 10.11817/j.issn.1672-7347.2018.01.002 1 0 0 47 Humans|Female|Mice|Animals|*Primary Ovarian Insufficiency|*Menopause, Premature|Atretic Follicle|Ovary|Mesenchymal Stem Cell Transplantation|Bone Marrow Mesenchymal Stem Cells|Granulosa Cells|Cyclophosphamide|Intraperitoneal Injection|Cells, Cultured|Disease Models, Animal 103 NOBOX 29670080 Cell Death Dis 2018 PMC5906686 10.1038/s41419-018-0492-2 3 0 0 47 Pregnancy|Humans|Female|Mice|Animals|Adolescent|Meiosis|*Oogenesis|Oocytes|Ovaries|Ovarian Follicle|*Fetus|Meiotic Prophase I|Apoptosis|*Prenatal Care|*Starvation|Animals, Newborn|Gene Expression Regulation, Developmental|Reproduction|Cell Differentiation 103 NOBOX 29615536 Aging (Albany NY) 2018 PMC5892698 10.18632/aging.101405 4 4 0 47 Female|Animals|Mice|*Melatonin|*Nicotine|Ovarian Follicle|Oocyte|Ovaries|Germ Cell|Animals, Newborn|Signal Transduction|Apoptosis 103 NOBOX 29410391 Aging (Albany NY) 2018 PMC5842841 10.18632/aging.101376 4 10 0 47 Pregnancy|Female|Mice|Animals|*Ovarian Follicle|Oocytes|*Autophagy|Ovaries|Germ Cell|Apoptosis|Animals, Newborn|Birth 103 NOBOX 29317212 Gen. Comp. Endocrinol. 2018 PMC5856633 10.1016/j.ygcen.2018.01.003 2 2 0 47 Cricetinae|Female|Animals|*Ovary|Ovarian Follicle|Siberian Hamsters|Receptors, FSH|Gonadotropins|Follicle Stimulating Hormone|Photoperiod|Ovulation|mRNA|*Sex Differentiation|*Complement Factor B|3'-(1-butylphosphoryl)adenosine 103 nos1ap 30544110 Neuropsychobiology 2018 10.1159/000493400 0 0 0 240 Humans|*Long QT Syndrome|Antipsychotics|Electrocardiography|Sudden Cardiac Death|Antidepressants|Heart Rate|Single Nucleotide Polymorphisms|Genotype|Risk Factor|Psychotic Disorders 183 nos1ap 30307500 Cereb. Cortex 2018 10.1093/cercor/bhy254 2 1 0 240 Humans|Mice|Animals|*Depression|Depressive Disorder, Major|*Cortex, Prefrontal|NOS1 protein, human|Nitric Oxide Synthase Type I|*Disease Models, Animal|neurabin|Nerve Tissue Proteins|Synapsins|Adaptor Proteins, Signal Transducing|Microfilament Proteins|Brain 183 nos1ap 30215713 Eur. Heart J. 2018 PMC6247660 10.1093/eurheartj/ehy502 2 0 0 240 Humans|*Genes, Modifier|*Sudden Cardiac Death|Long QT Syndrome|Arrhythmia, Cardiac|Brugada Syndrome|Channelopathies|Electrocardiography|Genetic Predisposition to Disease|Mutation 183 nos1ap 30157705 Mol Pain 2018 PMC6144507 10.1177/1744806918801224 2 5 0 240 Humans|NOS1 protein, human|*Nitric Oxide Synthase Type I|*Nociception|*Paclitaxel|*Cell Survival|HEK293 Cells|*Pain, Neuropathic|Hyperalgesia|Disks Large Homolog 4 Protein|N Methyl D Aspartate Receptors|Neurons|Analgesics|Enzyme Inhibitors|Antineoplastic Agents|NOS1AP protein, human|Adaptor Proteins, Signal Transducing 183 nos1ap 30086202 Fundam Clin Pharmacol 2018 10.1111/fcp.12405 0 0 0 240 Humans|*Opiate Substitution Treatment|*Long QT Syndrome|Methadone|Electrocardiography|SNPs|Risk Factor 183 nos1ap 29858554 J. Neurochem. 2018 10.1111/jnc.14478 2 27 0 240 Mice|Animals|NOS1 protein, human|*Nitric Oxide Synthase Type I|*Nuclear Factor-Kappab|*Hippocampus|pyrrolidine dithiocarbamic acid|Thiocarbamates|Neurons|Pyrrolidines|Adaptor Proteins, Signal Transducing|Maze Test|*Anxiety|Nitric Oxide|*Ligands 183 NPAS1 29917235 J. Physiol. (Lond.) 2018 PMC6117588 10.1113/JP276079 5 0 0 55 Mice|Animals|*Globus Pallidus|*Mice, Transgenic|*GABAergic Neurons|Action Potentials|Parvalbumins|Basal Ganglia|Nerve Tissue Proteins 35 NPAS1 29569009 Brain Struct Funct 2018 PMC5997534 10.1007/s00429-018-1652-y 7 0 0 55 Animals|*Corticotropin-Releasing Hormone|*Globus Pallidus|*Amygdala|*Synapse|*Neurons|Receptors, Corticotropin-Releasing Hormone|*Hypothalamus|Paraventricular Nucleus|Behavior, Animal|Stress, Psychological 35 Npas3 30509165 BMC Mol. Biol. 2018 PMC6276216 10.1186/s12867-018-0117-4 1 2 0 39 Humans|Animals|Mice|Transcription Factor|bHLH Transcription Factors|Helix-Loop-Helix Motifs|Nerve Tissue Proteins|Gene Expression Regulation|Neurogenesis|Mice, Knockout|Amino Acid Sequence|Sequence Homology, Amino Acid|NPAS3 protein, human 56 Npas3 30246428 J. Cell. Physiol. 2018 10.1002/jcp.27386 4 0 0 39 Pregnancy|Female|Humans|*Transcription Factors|*Embryonic Development|Blastocyst|Zygote|Gene Expression Regulation, Developmental|Morula|Genome|Oocytes|Embryo, Mammalian|Transcriptome|Gene Expression Profiling 56 Npas3 30089789 Mol. Psychiatry 2018 10.1038/s41380-018-0133-2 10 0 0 39 Animals|Humans|collapsin response mediator protein-1|Nerve Tissue Proteins|Dysbindin-1|Protein Aggregation, Pathological|TYRP1 protein, human|*Membrane Glycoproteins|Schizophrenia|Brain|Proteostasis|Neurons|Neurodegenerative Diseases|*Chronic Disease|Phosphoproteins 56 Npas3 29931044 Bioinformatics 2018 PMC6330004 10.1093/bioinformatics/bty462 0 0 0 39 Humans|*Epistasis, Genetic|*Cohort Studies|*Multifactorial Inheritance|Linkage Disequilibrium|Genome-Wide Association Study|Software|Computational Biology|Models, Genetic|Polymorphism, Single Nucleotide|Phenotype|Computer Simulation|*Academic Success|Scotland 56 Npas3 29805044 Am. J. Hum. Genet. 2018 PMC5992120 10.1016/j.ajhg.2018.04.005 6 0 0 39 Pregnancy|Humans|Female|*Translocation, Genetic|Karyotyping|Chromosome Aberrations|Prenatal Diagnosis|Amniocentesis|Chromosome Breakpoints|Ultrasonography, Prenatal|Phenotype 56 Npas3 29518182 DNA Res. 2018 PMC6105103 10.1093/dnares/dsy007 2 2 0 39 *Alleles|*Translocation, Genetic|Chromosome Aberrations|Karyotyping|Chromosome Mapping|DNA|*Chromosome 56 NPAT 30587245 J Ethnobiol Ethnomed 2018 PMC6307309 10.1186/s13002-018-0279-7 0 0 0 187 Animals|*Trees|Brazil|Fisheries|*Fishes|Conservation of Natural Resources|*Knowledge|Ecosystem|*Ships|Plant|Membrane Microdomains 121 NPAT 30411552 J Biomed Opt 2018 10.1117/1.JBO.23.11.116501 0 0 0 187 Photoacoustic Techniques|Microscopy|Tomography|Imaging, Three-Dimensional|Phantoms, Imaging|Spectrum Analysis|*Tomography, X-Ray Computed|Acoustic|Red Blood Cells 121 NPAT 30186493 Exp Ther Med 2018 PMC6122499 10.3892/etm.2018.6504 5 2 0 187 CCNE1 protein, human|Cyclin E|Cell Proliferation|*Genes, Tumor Suppressor|MicroRNAs|Oncogene Proteins|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|3' Untranslated Regions|*Genes, cdc 121 NPAT 29755656 Oncotarget 2018 PMC5945544 10.18632/oncotarget.24866 1 9 0 187 Humans|*Nanotubes, Carbon|Epigenesis, Genetic|Epithelial Cells|DNA Methylation|*Epigenetic|Cell Line 121 NPAT 29744889 J. Cell. Physiol. 2018 PMC6043376 10.1002/jcp.26741 5 2 0 187 Animals|CCNE1 protein, human|Cyclin E|Histone|CDK2 protein, human|Cyclin-Dependent Kinase 2|S Phase|Cell Cycle Proteins|Nuclear Proteins|Cell Cycle|*Cell Cycle Control|Chromatin|G1 Phase|Gene Expression Regulation|DNA Replication|Genes, cdc|mRNA|*Genomics 121 NPAT 29532868 Mol Med Rep 2018 PMC5928639 10.3892/mmr.2018.8715 3 38 0 187 Rats|Animals|*Osteogenesis|icariin|*Osteoblasts|Flavonoids|Cell Differentiation|Epimedium|Osteoporosis|Signal Transduction|Apoptosis|Calvaria 121 NPTX1 29486577 Exp. Biol. Med. (Maywood) 2018 PMC6582400 10.1177/1535370218761149 3 1 0 493 Rats|Animals|*Proteomics|Neurodegenerative Diseases|HDAC9 protein, human|*Histone Deacetylase|histone deacetylase 3|HTT protein, human|Huntingtin Protein|Repressor Proteins|Histone Deacetylase Inhibitors|Neurons|Nerve Tissue Proteins|Cell Death|Gene Expression Regulation 39 NPTX1 29345391 Cell Biol. Int. 2018 10.1002/cbin.10935 3 5 0 493 Mice|Animals|*Cyclin A2|CDK2 protein, human|*Cyclin-Dependent Kinase 2|*Cell Proliferation|*Downregulation|*Colon Cancer|Signal Transduction|Cell Line, Tumor|Xenograft Model Antitumor Assays 39 NREP 30558669 Microbiome 2018 PMC6297961 10.1186/s40168-018-0611-4 5 0 0 155 Humans|RNA, Ribosomal, 16S|*Microbiome|DNA, Bacterial|DNA, Ribosomal|Bacteria|Sequence Analysis, DNA|Gastrointestinal Microbiome|*Esophagus|Adenocarcinoma Of Esophagus|Esophageal Neoplasms|18S RRNA|Phylogeny|Adenocarcinoma 46 NREP 30230348 Am. J. Respir. Cell Mol. Biol. 2018 PMC6376409 10.1165/rcmb.2018-0028OC 1 4 0 155 Humans|Mice|Animals|Idiopathic Pulmonary Fibrosis|Bleomycin|Fibroblasts|Lung|Transforming Growth Factor beta1|*Transforming Growth Factor|Signal Transduction|Mice, Knockout|Disease Models, Animal|Cells, Cultured|Downregulation|P311 protein, mouse|Nerve Tissue Proteins 46 NREP 29507534 Biol Proced Online 2018 PMC5831220 10.1186/s12575-018-0067-8 2 0 0 155 Cluster Analysis|Sequencing, RNA|Oligonucleotide Array Sequence Analysis|*Gene Expression|Gene Expression Profiling|*Biochemical Phenomena 46 NREP 29483647 Nat. Struct. Mol. Biol. 2018 10.1038/s41594-018-0032-x 24 0 0 155 Animals|Mice|*RNA, Micro|RNA, Long Noncoding|RNA Degradation|3' UTR|Binding Sites|*Animal Behavior|Zebrafish|Transcription Factors 46 NREP 29480077 Mol Imaging 2018 PMC5833236 10.1177/1536012117749726 3 1 0 155 liposomal doxorubicin|*Doxorubicin|*Polyethylene Glycols|Nanoparticle|Radiopharmaceuticals|Positron-Emission Tomography|Liposomes|Tissue Distribution|Zirconium|*Electroporation|Cell Line, Tumor 46 NREP 29436600 Int. J. Mol. Med. 2018 10.3892/ijmm.2018.3485 2 1 0 155 Rats|Animals|*Ureteral Obstruction|*Epithelial-Mesenchymal Transition|*Adenovirus|*Fibrosis|integrin-linked kinase|*Protein-Serine-Threonine Kinases|Kidneys|*Transforming Growth Factor|*Adenoviridae Infections|Transforming Growth Factor beta1|SMAD2 protein, human|Smad2 Protein|CDH1 protein, human|E Cadherin|Kidney Tubules|Transductions, Signal|Chronic Kidney Disease|*Urinary Tract 46 NREP 29311449 Biosci Trends 2018 10.5582/bst.2017.01311 1 0 0 155 Humans|Rats|Animals|*Epithelial-Mesenchymal Transition|shenqi|*Fibrosis|*Drugs, Chinese Herbal|integrin-linked kinase|*Protein-Serine-Threonine Kinases|Smad Proteins|Kidney|Transforming Growth Factor beta1|Ureteral Obstruction|SMAD7 protein, human|Smad7 Protein|Signal Transduction|*Cytoplasmic Granules|Chronic Kidney Disease|CDH1 protein, human|E Cadherin|*Urinary Tract 46 NUCKS1 30371738 Carcinogenesis 2018 10.1093/carcin/bgy142 4 16 0 269 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Stomach Neoplasms|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|*Upregulation|Cell Migration|Cell Proliferation|*Receptor, IGF Type 1|IGF1R protein, human|Apoptosis|Downregulation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|*Stomach|*Transcriptional Activation 35 NUCKS1 30089309 Neurodegener Dis 2018 10.1159/000490427 2 0 0 269 *Parkinson Disease|Gene Regulatory Networks|MicroRNAs|DEAD-box RNA Helicases|Gene Expression Profiling|*RNA Interference 35 NUCKS1 30040709 J. Alzheimers Dis. 2018 PMC6087431 10.3233/JAD-170799 1 0 0 269 *Alzheimer Disease|Neurofibrillary Tangles|Brain|Neurons|Gene Expression Profiling|Biomarkers|Oxidative Phosphorylation 35 NUCKS1 29745862 BMC Neurosci 2018 PMC5998904 10.1186/s12868-018-0414-3 3 7 0 269 Humans|*Bipolar Disorder|*Genome-Wide Association Study|*Depressive Disorder, Major|Quality of Life|*Schizophrenia|SNPs|Genetic Predisposition to Disease|Genetic Loci|Allele|Genomics|Brain 35 NUCKS1 29619377 Biomed Res Int 2018 PMC5830027 10.1155/2018/7969068 2 10 0 269 Nuclear Protein|Phosphoproteins|Stability, Genome|Casein Kinase II|Phosphorylation|Gene Expression Regulation|Chromatin Assembly and Disassembly|*Biomarkers 35 NUCKS1 29607885 Genes Genet. Syst. 2018 10.1266/ggs.17-00038 1 1 0 269 Male|Humans|Female|*Parkinson Disease|Genome-Wide Association Study|SNPs|Asian|Genetic Predisposition to Disease|Genetic Association Studies|Gene Frequency|Allele|Genotype|Restriction Fragment Length Polymorphism|Ethnic Groups|Case-Control Studies|China 35 NUCKS1 29462394 Inflamm. Bowel Dis. 2018 10.1093/ibd/izx071 1 0 0 269 *Colitis, Ulcerative|*Recombinational DNA Repair|*DNA Damage|Colorectal Cancer|DNA Repair|DNA Breaks, Double-Stranded|Genomic Instability|Colon|Histones|*DNA Marker 35 OGFR 30541348 Exp. Biol. Med. (Maywood) 2018 PMC6348594 10.1177/1535370218817746 0 2 0 69 Mice|Animals|Naltrexone|Experimental Autoimmune Encephalomyelitis|methionine-enkephalin receptor|Receptors, Opioid|Enkephalin, Methionine|Multiple Sclerosis|Narcotic Antagonists|Disease Models, Animal|Cell Proliferation 102 OGFR 30425572 Cancer Manag Res 2018 PMC6201847 10.2147/CMAR.S178343 1 9 0 69 *Methionine Enkephalin|*Stomach Neoplasms|*G1 Phase Cell Cycle Checkpoints|*Caspase-Dependent Apoptosis|Cell Proliferation|Cell Line, Tumor 102 OGFR 30343258 Int. Immunopharmacol. 2018 10.1016/j.intimp.2018.10.023 1 3 0 69 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Stomach Neoplasms|*Methionine|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Pathway|*Macrophage|Apoptosis|*Racemethionine|Methionine Enkephalin|Cell Proliferation|Upregulation|Cell Line, Tumor|Cytokines|IL10 protein, human|IL10 102 OGFR 30246052 Am J Clin Exp Urol 2018 PMC6146159 1 4 0 69 Male|Humans|methionine-enkephalin receptor|zeta receptor|*Receptors, Opioid|Naltrexone|*Prostate Cancer|OPRM1 protein, human|Receptor, mu Opioid|Enkephalins|*Androgens|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Analgesics, Opioid|Immunohistochemistry 102 OGFR 30081203 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.07.146 0 6 0 69 Female|Mice|Animals|*Tranexamic Acid|*Skin Aging|*C57BL Mice|*Ultraviolet Rays|*Skin Diseases|*Eyes|Skin|*Plasma 102 OGFR 29628931 Front Plant Sci 2018 PMC5876317 10.3389/fpls.2018.00252 4 13 0 69 102 OGFR 29307283 Exp. Biol. Med. (Maywood) 2018 PMC6022923 10.1177/1535370217749830 2 0 0 69 Mice|Animals|*Encephalomyelitis, Autoimmune, Experimental|*Multiple Sclerosis|*Enkephalin, Methionine|Myelin-Oligodendrocyte Glycoprotein|Naltrexone|Receptors, Opioid|Mice, Inbred C57BL|Cell Proliferation|Cytokines 102 OLFML3 30416854 Am J Cancer Res 2018 PMC6220148 1 3 0 48 Neoplasm Proteins|Repressor Proteins|Cell Line, Tumor|NF-kappa B|Down-Regulation|Cell Movement|*Neoplastic Processes|RNA, Messenger|Transfection|Histone Demethylases 21 OLFML3 30093905 Front Immunol 2018 PMC6070609 10.3389/fimmu.2018.01728 6 7 0 48 Animals|*Microglia|Smad2 Protein|Transforming Growth Factor beta1|Signal Transduction|Animals, Newborn 21 OLFML3 29948944 Mol. Neurobiol. 2018 10.1007/s12035-018-1156-z 2 0 0 48 *Microglia|Anti-Inflammatory Agents|Dexamethasone|Phagocytosis|Glucocorticoid|Cells, Cultured|Cell Proliferation 21 OLFML3 29878111 Hum. Mol. Genet. 2018 PMC6077792 10.1093/hmg/ddy211 5 0 0 48 Humans|*C-Reactive Protein|Linkage Disequilibrium|Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genotype|Genetic Predisposition to Disease|European Continental Ancestry Group|HNF1A protein, human|Hepatocyte Nuclear Factor 1-alpha|*Population Genomics|Genetic Variation|Ethnic Groups|Inflammation|Biomarkers|*Epidemiological Study|PLA2G6 protein, human|Group VI Phospholipases A2|HACL1 protein, human 21 ONECUT2 30478421 Nat. Med. 2018 PMC6614557 10.1038/s41591-018-0241-1 17 7 0 153 Humans|Male|Mice|Animals|AR protein, human|Androgen Receptor|*Androgens|ONECUT2 protein, human|*Homeodomain Proteins|Prostatic Neoplasms, Castration-Resistant|*Genes, Homeobox|Hepatocyte Nuclear Factor 3-alpha|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|Cell Proliferation|Signal Transduction|Xenograft Model Antitumor Assays 59 ONECUT2 30323194 Transl Psychiatry 2018 PMC6189064 10.1038/s41398-018-0272-x 2 0 0 153 Humans|*Psychosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genetic Association Studies|HLA DRB1|Lupus Erythematosus, Systemic|Genome-Wide Association Study|*Sequencing, Next-Generation|Phenotype|Autoimmune Diseases|Case-Control Studies|ONECUT2 protein, human|Transcription Factors|Homeodomain Proteins 59 ONECUT2 30309818 Eur Urol Focus 2018 10.1016/j.euf.2018.09.016 4 0 0 153 Humans|*Hematuria|*Urinary Bladder Neoplasms|ONECUT2 protein, human|*Homeodomain Proteins|*Transcription Factors|Biomarkers, Tumor|DNA Methylation|*Urinary Tract|Nuclear Proteins|POU4F2 protein, human|Transcription Factor Brn-3B 59 ONECUT2 29737581 Cancer Sci. 2018 PMC6029829 10.1111/cas.13633 7 30 0 153 Mice|Animals|Female|Humans|*Ovarian Cancer|Vascular Endothelial Growth Factor A|*Carcinoma, Ovarian Epithelial|*Cell Proliferation|ONECUT2 protein, human|*Homeodomain Proteins|*Transcription Factor|*Neovascularization, Pathologic|Epithelial-Mesenchymal Transition|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Xenograft|*Neoplastic Processes|Signal Transduction|Adenocarcinoma 59 OSCP1 30076719 J. Cell. Physiol. 2018 PMC6202131 10.1002/jcp.26930 4 4 0 406 Animals|Humans|CCND1 protein, human|*Cyclin D1|Remodelling, Airway|Smooth Muscle Cell|Cell Proliferation|miRNA|Cell Movement|Asthma|Signal Transduction|Transforming Growth Factor beta1|Downregulation|PDGF-BB|Proto-Oncogene Proteins c-sis|Cells, Cultured|Muscle, Smooth|MIRN638 microRNA, human 62 OSR2 30583699 J. Dent. Res. 2018 10.1177/0022034518811861 1 0 0 68 Humans|Mice|Animals|Palate|PAX1 transcription factor|Paired Box Transcription Factors|Cleft Palate|Gene Expression Regulation, Developmental|Morphogenesis|Mesenchyme|Wnt Pathways|Cell Proliferation|In Situ Hybridization|PAX9 protein, human|PAX9 Transcription Factor|Ldb1 protein, mouse|DNA-Binding Proteins|LIM Domain Proteins 79 OSR2 30234390 Genet Test Mol Biomarkers 2018 10.1089/gtmb.2018.0064 0 0 0 68 Humans|Blepharophimosis, Ptosis, and Epicanthus Inversus|*Blepharophimosis|*Mutation, Missense|*Forkhead Box Protein L2|*Skin Abnormalities|*Urogenital Abnormalities|Pedigree|*Chinese|Genetic Association Studies|Mutation|Forkhead Transcription Factors|FOXL2 protein, human 79 OSR2 29526646 Reprod. Toxicol. 2018 10.1016/j.reprotox.2018.03.004 1 2 0 68 Mice|Animals|*Cleft Palate|Palate|FGFR2 protein, human|Receptor, Fibroblast Growth Factor, Type 2|Mesoderm|Signal Transduction|*Mesenchymal Stem Cells|Gene Expression Regulation, Developmental|Fibroblast Growth Factor|Cell Proliferation|In Situ Hybridization 79 OSR2 29511024 Development 2018 10.1242/dev.161208 3 0 0 68 Animals|*Transcription Factors|*Genome|*Chickens|Zinc Finger|Gene Expression Regulation, Developmental|Cell Differentiation|Limb|*Connective Tissue|In Situ Hybridization 79 OTOG 30139988 Eur. J. Hum. Genet. 2018 PMC6244407 10.1038/s41431-018-0218-z 7 0 0 16 Humans|*Arabs|Israel|HEK293 Cells|*Hearing Loss|DNA Mutational Analysis|Pedigree|Deafness|Connexins|Homozygote|Exon|Mutation|Myosins|Alleles|Membrane Proteins|OTOF protein, human|TBC1D24 protein, human|Nerve Tissue Proteins 35 OTOG 30097855 Fam. Cancer 2018 10.1007/s10689-018-0099-x 2 0 0 16 Humans|Adult|Mice|Animals|*Immunoblastic Lymphadenopathy|Peripheral T-Cell Lymphoma|Lymphoma, T-Cell|Isocitrate Dehydrogenase|Mutation|Exome|Genetic Predisposition|Phenotype|rhoA GTP-Binding Protein|Biomarkers, Tumor|DNA-Binding Proteins|T-Lymphocytes, Helper-Inducer|GNL3L protein, human|Nuclear Proteins|GTP-Binding Proteins|Ttc36 protein, mouse|Membrane Proteins|Mitochondrial Proteins 35 OTOG 29976152 BMC Neurosci 2018 PMC6034256 10.1186/s12868-018-0438-8 1 4 0 16 Humans|Mice|Animals|*Encephalitis Viruses, Tick-Borne|*Chromosomes, Human, Pair 7|*BALB C Mice|Encephalitis, Tick-Borne|Chromosome Mapping|IL10 protein, human|IL10|DC-specific ICAM-3 grabbing nonintegrin|Lectins, C-Type|Disease Susceptibility|CCR5 protein, human|Receptors, CCR5|Receptors, Cell Surface|Cell Adhesion Molecules|Oas1b protein, mouse|2',5'-Oligoadenylate Synthetase 35 OTOG 29800624 Eur J Med Genet 2018 10.1016/j.ejmg.2018.05.018 4 0 0 16 Child|Male|Humans|Child, Preschool|Nonsyndromic Deafness|*Deafness|Homozygote|Phenotype|Mutations|Alleles|Pedigree|Membrane Glycoproteins|Vestibule, Labyrinth 35 OTOP1 29371428 Science 2018 PMC5845439 10.1126/science.aao3264 24 1 0 24 Animals|Mice|*Protons|*Ion Channel|Taste Buds|Ion Channel Gating|*Ions|*Biological Evolution|Signal Transduction|Membrane Proteins 23 Ovol1 30523637 J. Cell. Physiol. 2018 10.1002/jcp.27821 0 1 0 127 Animals|BMP2 protein, human|*Bone Morphogenetic Protein 2|*Osteogenesis|*Cell Differentiation|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteoblasts|Transcription Factors|Transforming Growth Factor beta|Osteocalcin|Cell Line|Alkaline Phosphatase|Messenger RNA|Signal Transduction 62 Ovol1 30086823 Reprod. Fertil. Dev. 2018 10.1071/RD18034 0 1 0 127 Humans|Male|Animals|*Testis|*Triploidy|*Transcriptome|*Infertility, Male|Spermatogenesis|Spermatozoa|Sperm Flagellum|Spermatids|*Cyprinidae|Histone|Diploid|Meiosis|Reproduction 62 Ovol1 29972223 Acta Derm. Venereol. 2018 10.2340/00015555-3003 5 3 0 127 AHR protein, human|*Aryl Hydrocarbon Receptor|*Dermatitis, Atopic|*Antioxidants|*Basic Helix-Loop-Helix Transcription Factors|filaggrin|Intermediate Filament Proteins|*Epidermis|NFE2L2 protein, human|NF-E2-Related Factor 2|Keratinocytes|*Phytochemicals|*Eczema|*Cell Differentiation|Skin|Reactive Oxygen Species|Oxidative Stress|Signal Transduction 62 Ovol1 29866992 Int J Mol Sci 2018 PMC6032276 10.3390/ijms19061654 6 2 0 127 62 Ovol1 29749538 Oncol. Rep. 2018 PMC6059744 10.3892/or.2018.6426 11 3 0 127 Humans|*Prognosis|*Carcinoma, Squamous Cell|CpG Islands|DNA Methylation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Epigenesis, Genetic|Lung Cancer|Promoter Regions, Genetic|*Carcinoma, Non-Small-Cell Lung|Gene Expression Profiling|mRNA|Cobl protein, human|Microfilament Proteins 62 Ovol1 29454536 J. Dermatol. Sci. 2018 10.1016/j.jdermsci.2018.02.005 4 8 0 127 Humans|*Skin|Keratinocytes|Intermediate Filament Proteins|Dermatitis, Atopic|Receptors, Aryl Hydrocarbon|Membrane Proteins|Up-Regulation|Signal Transduction|OVOL1 protein, human|DNA-Binding Proteins|Transcription Factors|Ovol2 protein, human 62 Ovol1 29377304 J. Cell. Biochem. 2018 10.1002/jcb.26721 2 11 0 127 Pregnancy|Female|Humans|*Trophoblasts|STAT5A protein, human|STAT5B protein, human|*STAT5b Transcription Factor|Cell Fusion|Protein Kinase A|Cyclic AMP|Chorionic Gonadotropin|Signal Transduction|Forskolin|Placenta|Choriocarcinoma|Gene Expression Regulation|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Tumor Suppressor Proteins|NR4A3 protein, human|DNA-Binding Proteins 62 OVOL2 30587547 Clin. Cancer Res. 2018 10.1158/1078-0432.CCR-18-2364 4 0 0 96 Humans|*Dasatinib|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|ErbB Receptors|Epithelial-Mesenchymal Transition|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Cell Line, Tumor|*Carcinoma|Gene Expression Regulation, Neoplastic|Transforming Growth Factor beta|Gene Knockdown Techniques|Gene Expression Profiling 53 OVOL2 30542118 Oncogene 2018 10.1038/s41388-018-0615-3 0 1 0 96 Mice|Animals|*Poly ADP Ribosylation|Proteomics|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|ADP Ribose, Poly|Poly ADP Ribose Polymerase|Protein Processing, Post-Translational|DNA Repair|Poly(ADP-ribose) Polymerase Inhibitors|*Aneuploidy|DNA Damage|E3 Ubiquitin Ligase|Protein Binding|*Cell Death|Protein Domains|Centrosome 53 OVOL2 30413481 EMBO Rep. 2018 PMC6322385 10.15252/embr.201846273 6 0 0 96 Transcription Factors|Zinc Finger E-box-Binding Homeobox 1|Epithelial-Mesenchymal Transition|Cell Proliferation|Keratinocytes|Cell Differentiation|Skin|Wound Healing 53 OVOL2 29872308 Onco Targets Ther 2018 PMC5973319 10.2147/OTT.S157119 4 23 0 96 Male|*Epithelial-Mesenchymal Transition|*Osteosarcoma|Zinc Finger E-box-Binding Homeobox 1|Transcription Factor|Homeodomain Proteins|Cell Movement|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Down-Regulation|Hepatocellular Carcinoma|Cell Line, Tumor|Liver Neoplasms 53 OVOL2 29721076 Theranostics 2018 PMC5928884 10.7150/thno.25181 0 0 0 96 *Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Epithelial-Mesenchymal Transition|Carcinoma|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cadherins|Down-Regulation|Signal Transduction|Transcription Factors|Neoplasm Transplantation 53 OVOL2 29721073 Theranostics 2018 PMC5928881 10.7150/thno.24003 18 1 0 96 53 OVOL2 29499165 Am. J. Hum. Genet. 2018 PMC5985340 10.1016/j.ajhg.2018.02.002 7 10 0 96 Humans|Corneal Dystrophy, Posterior Polymorphous, 1|Endothelial Cells|Corneal Dystrophy, Posterior Polymorphous, 3|Corneal Dystrophies, Hereditary|Corneal endothelial dystrophy type 2|*Mutations|Transcription Factors|Homeodomain Proteins|Exons|Promoter Regions, Genetic|Corneal Endothelium|Pedigree|Zinc Finger E-box-Binding Homeobox 1|Intron|Gene Expression Regulation|GRHL2 protein, human|DNA-Binding Proteins 53 OVOL2 29454536 J. Dermatol. Sci. 2018 10.1016/j.jdermsci.2018.02.005 4 8 0 96 Humans|*Skin|Keratinocytes|Intermediate Filament Proteins|Dermatitis, Atopic|Receptors, Aryl Hydrocarbon|Membrane Proteins|Up-Regulation|Signal Transduction|OVOL1 protein, human|DNA-Binding Proteins|Transcription Factors|Ovol2 protein, human 53 OVOL2 29394105 FASEB J. 2018 10.1096/fj.201701131RR 5 0 0 96 Pregnancy|Female|Cattle|Animals|*Trophoblasts|*Epithelial-Mesenchymal Transition|*Down-Regulation|*Transcription Factor|*Implantation, Embryo|*Endometrium|CDH1 protein, human|E Cadherin|Uterus|*Gene Expression Regulation|Epithelium|Vimentin|Cells, Epithelial|Embryo, Mammalian|Antigens, CD|Cell Line|Up-Regulation|Cultured Cells 53 oxsr1 30054970 Proteomics Clin Appl 2018 10.1002/prca.201800041 0 0 0 594 Giant Cell Tumor of Bone|Bone Neoplasms|Lung Neoplasms|*Bone|Biomarkers, Tumor|Neoplasm Recurrence, Local 38 oxsr1 29802697 Asian Pac. J. Cancer Prev. 2018 PMC6031819 10.22034/APJCP.2018.19.5.1343 5 10 0 594 *Carcinoma, Squamous Cell|*Mouth Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|DNA Methylation|Cell Transformation, Neoplastic|Promoter Regions, Genetic|Carcinogenesis|Downregulation|Up-Regulation|*Oxidative Stress 38 P2RY8 30487598 Leukemia 2018 PMC6398588 10.1038/s41375-018-0297-4 2 0 0 46 Humans|*Down Syndrome|*Single-Cell Analysis|CRLF2 protein, human|Cytokine Receptor|Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Leukemia, Myeloid, Acute|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|In Situ Hybridization, Fluorescence|Gene Rearrangement|Janus Kinase 2|Mutation 52 P2RY8 29982439 Gigascience 2018 PMC6065480 10.1093/gigascience/giy079 2 0 0 46 *RNA|*Sequencing, RNA|*Whole Exome Sequencing|Receptors, Cytokine|Oncogene Proteins, Fusion|Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Base Sequence|Receptors, Purinergic P2Y|*Computers 52 P2RY8 29786757 Int. J. Hematol. 2018 10.1007/s12185-018-2474-7 0 0 0 46 *DNA Copy Number Variations|*Acute Lymphoblastic Leukemia|Ikaros Transcription Factor|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Cyclin-Dependent Kinase Inhibitor p15|PAX5 Transcription Factor|Cyclin-Dependent Kinase Inhibitor p16|*Acute Disease|Gene Deletion|*Cell Lines 52 P2RY8 29507076 Blood Adv 2018 PMC5851421 10.1182/bloodadvances.2017014704 5 1 0 46 Child|Humans|*Prognosis|Genome-Wide Association Study|Ikaros Transcription Factor|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Fusion Proteins, bcr-abl|Gene Deletion|Mutation|IKZF1 protein, human 52 P2RY8 29407587 Leuk. Res. 2018 10.1016/j.leukres.2018.01.012 0 1 0 46 Child|Humans|*Neoplasm, Residual|*DNA Copy Number Variations|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Ikaros Transcription Factor|*Burkitt Lymphoma|Gene Dosage|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Gene Deletion|Genes, p16|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Cohort Studies|Multiplex Ligation-Dependent Probe Amplification|SHOX protein, human|Short Stature Homeobox Protein 52 PACRG 30324028 PeerJ 2018 PMC6186407 10.7717/peerj.5759 0 1 0 62 Humans|Animals|Horses|*RNA|Sequence Analysis, RNA|High-Throughput Nucleotide Sequencing|Exome|Software|Gene Expression Profiling|Genetic Variation|Polymorphism, Single Nucleotide|*Asthma 68 PACRG 30296568 Gene 2018 10.1016/j.gene.2018.10.010 3 0 0 62 Humans|*Promoter Regions, Genetic|*Colorectal Cancer|SNPs|Genetic Predisposition to Disease|*Asian Continental Ancestry Group|*Colonic Neoplasms|Haplotype|Genotype|Alleles|DNA Methylation|RFLP|Case-Control Studies|Ethnic Groups 68 PACRG 29862454 Immunogenetics 2018 10.1007/s00251-018-1065-3 0 0 0 62 Humans|Cattle|Animals|Female|*Milk|*Genome-Wide Association Study|Streptococcus uberis|*Streptococcus|Mastitis, Bovine|Lactation|Dairy Industry|Streptococcal Infections|Mammary Glands, Animal|Counts, Cell|*Leukocytes|*Phenotypes|Mastitis 68 PACRG 29843777 Genome Med 2018 PMC5975672 10.1186/s13073-018-0549-y 3 7 0 62 Humans|Animals|*Heterotaxy Syndrome|*DNA Copy Number Variations|Body Patterning|Zebrafish Proteins|Zebrafish|Genetic Association Studies|Genotype 68 PACRG 29760428 Sci Rep 2018 PMC5951884 10.1038/s41598-018-25766-1 3 4 0 62 Mice|Animals|*Knockout Mouse|parkin protein|*Ubiquitin-Protein Ligases|Substantia Nigra|Dopaminergic Neurons|Parkinson Disease|Dopamine|Parkinsonian Disorders|Promoter Regions, Genetic|Mutations|Pacrg protein, mouse|Proteins 68 pacs2 30415949 Mol. Cell 2018 PMC6309500 10.1016/j.molcel.2018.10.007 4 3 0 228 *Sirtuin 1|*Insulin|*Insulin, Regular, Human|Adaptor Proteins, Signal Transducing|Signal Transduction|Cell Line, Tumor 38 pacs2 30205097 Life Sci. 2018 10.1016/j.lfs.2018.09.019 4 2 0 228 Male|Humans|Rats|Animals|*Streptozocin|sodium nitrate|Diabetes Mellitus, Experimental|*Testis|*Infertility, Male|*Nitrates|*Apoptosis|Spermatogenesis|Spermatozoa|Sperm Count|Sperm Motility|Oxidative Stress|Testicular Diseases|Antioxidants|Rats, Wistar|Diabetes Complication|Testosterone|Insulin 38 pacs2 29670108 Cell Death Dis 2018 PMC5906598 10.1038/s41419-018-0470-8 1 7 0 228 Humans|*Down-Regulation|*Stomach Neoplasms|Epigenesis, Genetic|p300-CBP Protein|*Stomach|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Mitochondria|Transcription Factors|Signal Transduction|PACS1 protein, human|Vesicular Transport Proteins|mRNA|PACS2 protein, human 38 pacs2 29656858 Am. J. Hum. Genet. 2018 PMC5986694 10.1016/j.ajhg.2018.03.005 1 0 0 228 Child, Preschool|Humans|Infant, Newborn|Child|*Heterozygote|Phenotype|*Musculoskeletal Abnormalities|Spasms, Infantile|Sequencing, Whole Exome|*Cerebellar Diseases|Neurodevelopmental Disorders|Mutation, Missense|*Nervous System Malformations|PACS1 protein, human|Vesicular Transport Proteins|PACS2 protein, human 38 pacs2 29312533 Oncotarget 2018 PMC5752446 10.18632/oncotarget.22661 2 10 0 228 Mice|Animals|*Colitis|Dextran Sulfate|ADAM17 protein, human|ADAM-17|Colon|Intestinal Mucosa|Mice, Inbred C57BL|ErbB Receptors|Disease Models, Animal|Regeneration 38 PAGE4 30413085 Biomolecules 2018 PMC6315554 10.3390/biom8040140 5 0 0 57 *Intrinsically Disordered Proteins|*Fluorescence Resonance Energy Transfer|Protein Conformation|Molecular Dynamics Simulation|Phosphorylation|Fluorescence 31 PAGE4 29914187 J Clin Med 2018 PMC6025510 10.3390/jcm7060156 4 0 0 57 Humans|Male|*Prostate|*Dancing|Prostate Cancer|*Proteins|Antigens, Neoplasm|Protein Conformation|Phosphorylation|Androgens|Cell Line, Tumor|Transcriptional Activation|Downregulation|PAGE4 protein, human 31 PAGE4 29758263 J. Mol. Biol. 2018 PMC6045464 10.1016/j.jmb.2018.05.011 8 5 0 57 Humans|Male|*Prostate|*Molecular Dynamics Simulation|*Prostate Cancer|AR protein, human|Androgen Receptor|Clk dual-specificity kinases|Protein-Serine-Threonine Kinases|Protein-Tyrosine Kinases|Phosphorylation|Protein Conformation|Antigens, Neoplasm|Signal Transduction|Cell Line, Tumor|Protein Structure, Secondary|PAGE4 protein, human 31 PALMD 29511194 Nat Commun 2018 PMC5840367 10.1038/s41467-018-03252-6 15 3 0 58 Genome-Wide Association Study|*Aortic Valve Stenosis|Aortic Valve|Heart Disease, Valvular|Calcinosis|Coronary Artery Disease|Odds Ratio|Iceland 20 PALMD 29511167 Nat Commun 2018 PMC5840407 10.1038/s41467-018-03260-6 7 1 0 58 Humans|Aortic Valve, Calcification of|*Aortic Valve|*Transcriptome|*Aortic Valve Stenosis|*Calcinosis|Genome-Wide Association Study|*Genes, Regulator|Palmd protein, mouse|Membrane Proteins|PALMD protein, human 20 panx3 30556206 J. Cell. Biochem. 2018 10.1002/jcb.28108 3 10 0 117 Male|Mice|Animals|*Down-Regulation|*Mice, Inbred C57BL|*Wnt Pathway|*Osteoblasts|MIRN367 microRNA, mouse|MicroRNAs|Cell Proliferation|beta Catenin|*Catenins|Apoptosis|Cell Cycle|mRNA|Fracture Healing|*Bone Fracture|siRNA 67 panx3 30389492 J. Invest. Dermatol. 2018 10.1016/j.jid.2018.08.033 0 1 0 117 Mice|Animals|Junction Protein, Gap|Cell Differentiation|Osteoblasts|Gap Junctions|Cell Migration|Signal Transduction|Cell Proliferation|Chondrocytes|Keratinocytes|Skin|Adenosine Triphosphate|Wound Healing|Cell Line|Collagen 67 panx3 29932112 Int J Mol Sci 2018 PMC6073767 10.3390/ijms19071837 2 1 0 117 Animals|*Glycosylation|Connexins|Protein Processing, Post-Translational|Nerve Tissue Proteins|Biotinylation|Cell Membrane|Protein Transport|Cell Movement 67 panx3 29780304 Front Mol Neurosci 2018 PMC5946002 10.3389/fnmol.2018.00135 2 7 0 117 Mice|Animals|*Knockout Mouse|*Vomeronasal Organ|Connexins|Nerve Tissue Proteins|Panx1 protein, mouse|Panx2 protein, mouse 67 panx3 29744875 J. Cell. Physiol. 2018 10.1002/jcp.26629 0 0 0 117 Humans|Mice|Animals|*Muscle Development|*Muscular Dystrophy, Duchenne|Connexins|Muscle, Skeletal|Myoblasts|Cell Differentiation|Nerve Tissue Proteins|Regeneration|PANX1 protein, human|Panx1 protein, mouse 67 panx3 29735531 J. Biol. Chem. 2018 PMC6005452 10.1074/jbc.RA118.001825 5 1 0 117 Mice|Animals|*Chondrocytes|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|*Chondrogenesis|*Cell Differentiation|*Cell Proliferation|SMAD4 protein, human|*Smad4 Protein|SOX9 Transcription Factor|Osteogenesis|Collagen Type II|Gene Expression Regulation, Developmental|Signal Transduction|Hypertrophy|*Cell Cycle|Runx2 protein, mouse 67 panx3 29357945 BMC Res Notes 2018 PMC5778636 10.1186/s13104-018-3125-z 1 2 0 117 Humans|Endothelial Cells|Connexins|Cell Differentiation|Nerve Tissue Proteins|*B Cells|Human Embryonic Stem Cells|Cell Lines|Induced Pluripotent Stem Cells|mRNA 67 PARM1 30527387 J Biomech 2018 10.1016/j.jbiomech.2018.11.036 0 0 0 49 Humans|*Walking Speed|*Limb, Lower|Walking|Kinematics|Gait|Ankle Joint|Weight-Bearing|Knee Joint|Hip Joint|Hip|Knee|Ankle|Muscular Fatigue|Exercise Test|Soldiers|Australia 20 PARM1 30447974 J. Dairy Sci. 2018 10.3168/jds.2018-15358 3 1 0 49 Pregnancy|Humans|Cattle|Animals|Female|*Parity|*Lactation|*Chorionic Gonadotropin|Artificial Insemination|*Fertility|Progesterone|Gonadotropin-Releasing Hormone|*Genotype 20 PARM1 30194076 Cancer Genomics Proteomics 2018 PMC6199573 10.21873/cgp.20094 3 2 0 49 *Histone Deacetylase Inhibitors|trichostatin A|*Transcriptome|BRAF protein, human|Proto-Oncogene Proteins B-raf|*Hydroxamic Acids|Melanoma, Cutaneous Malignant|Malignant Melanoma|Skin Neoplasms|Drug Resistance, Neoplasm|Protein Kinase Inhibitors|Cell Line, Tumor|Histone Deacetylases|MAP Kinase Signaling System|Mutation|Gene Expression Regulation, Neoplastic|*Molecular Targeted Therapy 20 PARP12 30154409 Cell Death Dis 2018 PMC6113207 10.1038/s41419-018-0906-1 3 28 0 93 Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Epithelial-Mesenchymal Transition|TGFB1 protein, human|Transforming Growth Factor beta1|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Down-Regulation|Transcription Factors|Cell Proliferation|Cell Line, Tumor|Up-Regulation|Signal Transduction|Genes, Tumor Suppressor|Mice, Nude|Fhl2 protein, mouse|Muscle Proteins 20 PARP12 30105925 Future Oncol 2018 PMC6331693 10.2217/fon-2018-0215 0 0 0 93 Female|Humans|*Poly(ADP-ribose) Polymerase Inhibitors|rucaparib|Neoplasm Recurrence, Local|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Indoles|BRCA2 Protein|Neoplasms, Glandular and Epithelial|BRCA1 Protein|PARP2 protein, human|Poly ADP Ribose Polymerase|Germ-Line Mutation|PARP3 protein, human|Platinum|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Cell Cycle Proteins|PARP10 protein, human 20 PARP12 29921658 Sci Signal 2018 PMC6434931 10.1126/scisignal.aas9332 12 9 0 93 Humans|Zika Virus|Zika Virus Infection|Proteins, Viral Nonstructural|Virus Replication|Type I Interferon|Antiviral Agents|A549 Cells|RNA Helicases|ADP Ribosylation|HEK293 Cells 20 PARP3 30442946 Cell Death Differ. 2018 PMC6748154 10.1038/s41418-018-0233-1 0 5 0 178 Humans|BRCA1 protein, human|*BRCA1 Protein|*Signal Transduction|PARP3 protein, human|*Poly(ADP-ribose) Polymerases|*Cell Cycle Proteins|Triple-Negative Breast Cancer|Epithelial-Mesenchymal Transition|Mechanistic Target of Rapamycin Complex 2|Rapamycin-Insensitive Companion of mTOR Protein|Cell Line, Tumor|*Neoplastic Processes|Cell Movement|RICTOR protein, human 80 PARP3 30397881 Dokl. Biochem. Biophys. 2018 10.1134/S1607672918050010 1 0 0 178 PARP3 protein, human|*Poly(ADP-ribose) Polymerases|*Base Excision Repair|*Cell Cycle Proteins|DNA Damage|DNA Break|DNA 80 PARP3 30213852 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6176633 10.1073/pnas.1801591115 2 0 0 178 Humans|Mice|Animals|PARP3 protein, human|*Poly(ADP-ribose) Polymerases|DNA End-Joining Repair|*Cell Cycle Proteins|DNA Breaks, Double-Stranded|Poly (ADP-Ribose) Polymerase-1|Immunoglobulin Class Switching|DNA Repair|DNA-Binding Proteins|Translocation, Genetic|Parp3 protein, mouse 80 PARP3 30105925 Future Oncol 2018 PMC6331693 10.2217/fon-2018-0215 0 0 0 178 Female|Humans|*Poly(ADP-ribose) Polymerase Inhibitors|rucaparib|Neoplasm Recurrence, Local|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Indoles|BRCA2 Protein|Neoplasms, Glandular and Epithelial|BRCA1 Protein|PARP2 protein, human|Poly ADP Ribose Polymerase|Germ-Line Mutation|PARP3 protein, human|Platinum|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Cell Cycle Proteins|PARP10 protein, human 80 PARP3 30039287 Breast Cancer Res. Treat. 2018 10.1007/s10549-018-4888-6 7 3 0 178 Humans|olaparib|*Vinorelbine|ME0328|*Phthalazines|PARP3 protein, human|*Piperazines|*Quinazolinones|*MCF-7 Cells|Poly(ADP-ribose) Polymerase Inhibitors|*Cell Cycle Proteins|Cell Line, Tumor|DNA Repair|Drug Resistance, Neoplasm|Apoptosis|NUMA1 protein, human|Antigens, Nuclear|Tankyrases|Nuclear Matrix-Associated Proteins 80 PARP3 29977351 Ther Adv Med Oncol 2018 PMC6024342 10.1177/1758835918778483 3 4 0 178 Humans|Female|rucaparib|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Indoles|Poly(ADP-ribose) Polymerase Inhibitors|PARP3 protein, human|Poly ADP Ribose Polymerase|PARP2 protein, human|Antineoplastic Agents|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Cell Cycle Proteins 80 PARP3 29676938 SLAS Discov 2018 10.1177/2472555218767843 1 0 0 178 *NAD|PARP2 protein, human|Poly(ADP-ribose) Polymerases|PARP3 protein, human|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Cell Cycle Proteins|DNA Repair|*Biotinylations 80 PARP3 29520010 Sci Rep 2018 PMC5843604 10.1038/s41598-018-22673-3 15 5 0 178 *B-DNA|PARP2 protein, human|*Poly ADP Ribose Polymerase|PARP3 protein, human|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|*Cell Cycle Proteins|Ribosylations, ADP|DNA Repair|DNA|DNA Breaks, Double-Stranded|ADP-Ribose|DNA Primers 80 parpbp 29805304 Int. J. Biol. Sci. 2018 PMC5968845 10.7150/ijbs.23945 4 4 0 100 Mice|Animals|*Stomach Neoplasms|Forkhead Box Protein M1|Neoplasm Invasiveness|Mice, Nude|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Forkhead Transcription Factors|Pancreatic Neoplasms|RNA Interference|Cell Proliferation|Signal Transduction|Tissue Array Analysis 25 PCAT6 30582215 J. Cell. Biochem. 2018 10.1002/jcb.28177 5 0 0 0 Humans|*RNA, Long Noncoding|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Lung Adenocarcinoma|Network, Gene|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Epigenesis, Genetic|*Cell Physiological Phenomena 23 PCAT6 30569799 Cell Cycle 2018 PMC6343696 10.1080/15384101.2018.1558872 9 5 0 0 Male|*RNA, Long Noncoding|Carcinoma, Non-Small-Cell Lung|*AIDS-Related Complex|Lung Cancer|*Apoptosis|Cell Proliferation|Enhancer of Zeste Homolog 2 Protein|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*RNA, Untranslated|Prognosis|Cell Movement|Cell Cycle|*Colon Cancer|*Colon 23 PCAT6 30464520 Onco Targets Ther 2018 PMC6219114 10.2147/OTT.S178597 7 6 0 0 Male|*Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|MicroRNAs|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 23 PCAT6 30314898 EBioMedicine 2018 PMC6286630 10.1016/j.ebiom.2018.10.004 19 3 0 0 *Carcinoma, Non-Small-Cell Lung|*RNA, Long Noncoding|*Lung Neoplasms|LATS2 protein, human|*Tumor Suppressor Proteins|*Protein-Serine-Threonine Kinases|*Oncogene|Enhancer of Zeste Homolog 2 Protein|Gene Expression Regulation, Neoplastic|Cell Proliferation|Prognosis|Apoptosis|Cell Line, Tumor|Tumorigenesis|Cell Movement|Epigenesis, Genetic|Signal Transduction 23 PCAT6 30178843 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201808_15718 5 5 0 0 *RNA, Micro|*Stomach Neoplasms|lncRNA|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Epithelial-Mesenchymal Transition|Cell Line, Tumor 23 PCDH11Y 30262602 Blood Adv 2018 PMC6177651 10.1182/bloodadvances.2018019513 2 0 0 45 Male|Humans|Female|*Graft vs Host Disease|*Hematopoietic Stem Cell Transplantation|Unrelated Donors|Transplantation Conditioning|Transplantation, Homologous|Histocompatibility|Histocompatibility Testing|HLA-DPB1 antigen|HLA-DP beta-Chains|Hematologic Neoplasms|*Stem Cell Transplantation|Minor Histocompatibility Antigens|Alleles|Disease-Free Survival|Chromosomes 24 PCDH8 30356120 Mol. Psychiatry 2018 PMC6482106 10.1038/s41380-018-0281-4 4 4 0 136 Humans|Male|Female|Animals|Mice|Adult|DNA Methylation|*Germ Lines|*Thyroid Hormones|CpG Islands|Genomic Imprinting|*Brain|Epigenesis, Genetic|*Epigenetic|Sperm|Iodide Peroxidase|Heredity|*Gene Expression|Phenotypes|Neurodevelopmental Disorders|PCDH8 protein, human|Cadherins|En1 protein, mouse|Homeodomain Proteins 88 PCDH8 29865037 Cancer Biomark 2018 10.3233/CBM-171137 1 1 0 136 Humans|*Hypopharyngeal Neoplasms|Promoter Regions, Genetic|*Genes, Tumor Suppressor|Prognosis|DNA Methylation|Cadherins|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease-Free Survival|mRNA|*Carcinoma|Downregulation|PCDH8 protein, human 88 PCDH8 29850813 Genome Biol Evol 2018 PMC6007540 10.1093/gbe/evy102 9 1 0 136 Animals|*Trout|Animal Migration|Salmonids|Freshwater|Seawater|SNPs 88 PCDH8 29325230 Cancer Sci. 2018 PMC5834795 10.1111/cas.13502 5 11 0 136 Mice|Animals|*Stomach Neoplasms|*Laminin|Mice, Nude|Upregulation|Gene Expression Regulation, Neoplastic|Cell Movement|Cadherins|*Neoplastic Processes|Cell Line, Tumor|RNA Interference|Cell Proliferation|Signal Transduction|Immunohistochemistry|Promoter Regions, Genetic|RNA, Messenger 88 PCDH8 29324532 Int. J. Gynecol. Cancer 2018 PMC5794251 10.1097/IGC.0000000000001169 2 8 0 136 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cadherins|Cell Line, Tumor|Cell Movement|Apoptosis|PCDH8 protein, human 88 Pcdh9 30588243 J Cancer 2018 PMC6299398 10.7150/jca.27993 1 2 0 84 Humans|Child|*Medulloblastoma|Cerebellar Neoplasms|*Signal Transduction|Hedgehog Proteins|beta Catenin|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Disease Progression|Mutation|Cohort Studies 63 Pcdh9 30345971 Elife 2018 PMC6197854 10.7554/eLife.40982 3 5 0 84 Animals|Mice|*Polyribosomes|Protein Interaction Mapping|*Base Sequence|*Sequencing, RNA|Protein Interaction Maps|*Whole Exome Sequencing 63 Pcdh9 30289472 Mol. Biol. Evol. 2018 PMC6278859 10.1093/molbev/msy190 2 0 0 84 Humans|Spain|African Continental Ancestry Group|*Genomics|European Continental Ancestry Group|Haplotypes|Alleles|Polymorphism, Single Nucleotide|Europe|North Africa|SLC6A1 protein, human|GABA Plasma Membrane Transport Proteins|PCDH20 protein, human|Nerve Tissue Proteins|Cadherins 63 Pcdh9 30076594 J. Comp. Neurol. 2018 PMC6312510 10.1002/cne.24507 4 0 0 84 *Motion Perception|*Mesencephalon|Retinal Ganglion Cells|Visual Pathways|Retina|Axons|Optic Tract|Brain Stem|Nerve, Optic 63 Pcdh9 30045829 EBioMedicine 2018 PMC6085584 10.1016/j.ebiom.2018.06.026 9 1 0 84 *Carcinoma, Hepatocellular|*Liver Neoplasms|Long Non-Coding RNA|Gene Expression Regulation, Neoplastic|Prognosis|Biomarkers, Tumor|Hep G2 Cells|Cell Proliferation|Cell Movement|Up-Regulation|Cell Line, Tumor 63 Pcdh9 29649113 Molecules 2018 PMC6017641 10.3390/molecules23040891 6 0 0 84 Humans|Female|*Ovarian Cancer|*Paclitaxel|Cell Line, Tumor|*Carcinoma, Ovarian Epithelial|Drug Resistance, Neoplasm|Topotecan|Gene Expression Regulation, Neoplastic 63 Pcdh9 29563929 Iran J Pathol 2018 PMC5844678 6 0 0 84 Humans|Male|Oligonucleotide Array Sequence Analysis|*Oncogenes|*Genetic Markers|Gene Expression Profiling|*Gene Expression|Gene Expression Regulation, Neoplastic|Algorithms|Prostatic Neoplasms 63 Pcdh9 29294296 J. Dent. Res. 2018 PMC6728575 10.1177/0022034517744189 5 0 0 84 Mice|Humans|Animals|Genome-Wide Association Study|X-Ray Microtomography|Quantitative Trait Loci|Mouse, Collaborative Cross|Chromosome Mapping|Genotype|Genetic Predisposition to Disease|Phenotype|Haplotypes|Crosses, Genetic|Polymorphism, Single Nucleotide|Aggressive Periodontitis|Chronic Periodontitis|Alveolar Bone Loss|LECT2 protein, human|Intercellular Signaling Peptides and Proteins|DUSP23 protein, human|Dual-Specificity Phosphatases 63 PCLO 30479371 Sci Rep 2018 PMC6258692 10.1038/s41598-018-35634-7 2 1 0 129 Male|Female|Mice|Animals|*Kinesin|*Synaptic Transmission|Synapse|Synaptic Vesicle|Neurons|SYP protein, human|Synaptophysin|Hippocampus|PCLO protein, human|Cytoskeletal Proteins|Neuropeptides|Receptors, N-Methyl-D-Aspartate|Kif21b protein, mouse 132 PCLO 30425904 Balkan J. Med. Genet. 2018 PMC6231308 10.2478/bjmg-2018-0010 0 0 0 129 Humans|*Depressive Disorder, Major|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Alleles|Genotype|Neuropeptides|Cytoskeletal Proteins 132 PCLO 30387133 J. Cell. Physiol. 2018 10.1002/jcp.27465 3 3 0 129 Humans|*Adipocytes, Brown|*Thermogenesis|Adipose Tissue, Brown|Uncoupling Protein 1|Adipose Tissue, White|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Transcription Factors|Mitochondrial Proteins|*Cytoplasm|Trans-Activators|Obesity|Signal Transduction 132 PCLO 30226068 Bratisl Lek Listy 2018 10.4149/BLL_2018_104 1 0 0 129 *Whole Exome Sequencing|Exome|*Schizophrenia|Pedigree|*Complement Factor B|Sequence Analysis, DNA|Polymorphism, Single Nucleotide 132 PCNP 30113165 Inorg Chem 2018 PMC6150681 10.1021/acs.inorgchem.8b01478 1 0 0 156 *Ligands|Molecular Structure|Nickel|*Imines|Catalysis|Crystallography, X-Ray|Models, Molecular 59 PCNP 30095730 Nurs Educ Perspect 2018 10.1097/01.NEP.0000000000000375 0 0 0 156 Humans|*Education, Nursing|Education, Nursing, Baccalaureate|Students, Nursing|*Problem Solving|Nursing Education Research|Problem-Based Learning|Thinking|Clinical Competence|*Outcome Assessment, Health Care 59 PCNP 30068515 Br J Ophthalmol 2018 PMC6582729 10.1136/bjophthalmol-2018-312195 1 0 0 156 Humans|*Diabetic Retinopathy|*Laser Coagulation|*Retina|Fluorescein Angiography|Retinal Vessels|Fundus Oculi|*Capillary|Tomography, Optical Coherence|*Choroid|Visual Acuity|*Postoperative Period|*Vitreous Body|Follow-Up Studies|Prospective Studies|4-maleimido-2,2,6,6-tetramethylpiperidinooxyl|*Cyclic N-Oxides|Oximetry|Diabetes Mellitus 59 PCNP 29716528 BMC Cancer 2018 PMC5930684 10.1186/s12885-018-4391-9 8 6 0 156 Humans|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Nuclear Protein|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|*Neuroblastoma|Cell Proliferation|Apoptosis|Cell Line, Tumor|MAP Kinase Signaling System 59 PCNP 29613873 Med Care 2018 10.1097/MLR.0000000000000908 2 0 0 156 United States|Humans|*Medicare|*Nurse Practitioners|*Primary Care|Primary Care Physicians|Practice Patterns, Nurses'|Practice Patterns, Physicians' 59 PCP4 30038708 Oncotarget 2018 PMC6049867 10.18632/oncotarget.25651 1 26 0 105 Humans|CYP19A1 protein, human|*Aromatase|*Upregulation|*Transcriptional Activation|*Cytochrome P-450 CYP1A1|Receptors, Estrogen|*Gene Expression|*Promoter Regions, Genetic|Cell Line, Tumor|Apoptosis|Cell Migration|Estrogens|Nerve Tissue Proteins 109 PCP4 31938214 Int J Clin Exp Pathol 2018 PMC6958178 0 0 0 105 Humans|*Aldosterone|*Proto-Oncogene Proteins c-akt|*AMP-Activated Protein Kinases|*Up-Regulation|*Adrenocortical Adenoma|*Adrenal Cortex Neoplasms|Hyperaldosteronism|*Cell Proliferation|Adrenal Cortex|Gene Expression Regulation, Neoplastic|Adenoma|*Transcriptional Activation|*Cell Cycle|mRNA|Tumor Cells, Cultured|Cell Line 109 PCP4 29294065 J. Clin. Endocrinol. Metab. 2018 10.1210/jc.2017-01996 3 4 0 105 *Aldosterone|*DNA Methylation|*Purkinje Cells|*Adrenocortical Adenoma|Adrenal Cortex Neoplasms|G Protein-Coupled Inwardly-Rectifying Potassium Channels|Cytochrome P-450 CYP11B2|Mutation|Gene Expression Regulation, Neoplastic|Calcium Signaling|Adenoma 109 pdia2 29707411 J Pediatr Genet 2018 PMC5916799 10.1055/s-0037-1612638 0 0 0 61 Infant|Humans|Infant, Newborn|Male|Female|*Classical Lissencephalies and Subcortical Band Heterotopias|*Lissencephaly|1-Alkyl-2-acetylglycerophosphocholine Esterase|Chromosome Deletion|Abnormalities, Multiple|In Situ Hybridization, Fluorescence|Microtubule-Associated Proteins|Brain|Face 23 PDLIM1 30582284 Proteomics 2018 10.1002/pmic.201800148 12 0 0 164 Humans|*Exosomes|*Proteome|Proteomics|Cancer-Associated Fibroblasts|*Colonic Neoplasms|Tumor Microenvironment|Colorectal Cancer|Fibroblasts|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 43 PDLIM1 29722072 Mol. Carcinog. 2018 10.1002/mc.22824 1 1 0 164 *Osteosarcoma|Telomerase|Telomere|Telomere Lengthening|Cell Line, Tumor|*Neoplastic Processes|Apoptosis|Downregulation|Transfection 43 PDLIM1 29574154 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.03.159 2 7 0 164 Humans|*Thyroid Cancer, Papillary|*Proteomics|Carcinoma, Papillary|Thyroid Neoplasms|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Up-Regulation|MicroRNAs|Downregulation|Cell Line, Tumor|Apoptosis|Biomarkers, Tumor|Pathway, ERK|PDLIM5 protein, human|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 43 PDLIM1 29463607 J. Lipid Res. 2018 PMC5880493 10.1194/jlr.M082651 6 1 0 164 Mice|Animals|*Mice, Knockout|*Atherosclerosis|*Macrophage|Apolipoproteins E|Plaque, Atherosclerotic|Inflammation|Mice, Inbred C57BL|MicroRNAs|Cell Proliferation|Signal Transduction|Upregulation|Disease Models, Animal 43 PDZD2 29948147 J. Cancer Res. Clin. Oncol. 2018 10.1007/s00432-018-2685-6 1 0 0 125 Humans|Male|*Prostate Cancer|Transcriptional Regulator ERG|Prostatectomy|Gene Fusion|Oncogene Proteins, Fusion|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Serine Endopeptidases|ERG protein, human 57 PDZD2 29673068 FEBS J. 2018 10.1111/febs.14474 0 0 0 125 Humans|Mice|Animals|*Transplantation Antigens|Graft Rejection|Graft Survival|Transplantation, Homologous|Transplant Donors|Major Histocompatibility Complex|T-Lymphocytes, Cytotoxic 57 PDZD2 29394082 Am. J. Respir. Crit. Care Med. 2018 PMC6058984 10.1164/rccm.201707-1493OC 10 0 0 125 Humans|*Genome-Wide Association Study|*Public Health|*Latinos|Genetic Loci|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Gene Frequency|Genotype|Chronic Obstructive Pulmonary Disease|Lung 57 PDZD7 30531642 Otol. Neurotol. 2018 10.1097/MAO.0000000000002054 0 0 0 36 Humans|*Usher Syndromes|DNA Mutational Analysis|Sequencing, Next-Generation|Pedigree|Genetic Association Studies|Mutation|Genotype|Nonsyndromic Deafness 30 PDZD7 30459346 Sci Rep 2018 PMC6244211 10.1038/s41598-018-35085-0 5 0 0 36 Humans|Usher syndrome, type 2A|Usher Syndrome, Type IC|Usher Syndrome, Type IG|*Usher Syndromes|Comparative Genomic Hybridization|*High-Throughput Nucleotide Sequencing|DNA Mutational Analysis|Mutations|Pedigree|Nonsense Mutations|Phenotype|CLRN1 protein, human|Membrane Proteins|Cep250 protein, human|Autoantigens|Cell Cycle Proteins 30 PDZD7 29796015 Neural Plast. 2018 PMC5896214 10.1155/2018/2062346 0 19 0 36 30 PDZD7 29588463 Sci Rep 2018 PMC5869593 10.1038/s41598-018-23520-1 3 0 0 36 Humans|*Syndromes|*Ciliopathies|*DNA Copy Number Variations|*Retinal Diseases|Sequencing, Next-Generation|Phenotypes|Bardet-Biedl Syndrome 12|Bardet-Biedl Syndrome|Mutation|Pedigree|Genotype|Retina|Cohort Studies|VPS13B protein, human|Vesicular Transport Proteins|ALMS1 protein, human|Proteins 30 PDZRN3 30066954 J. Cell. Physiol. 2018 10.1002/jcp.27113 1 0 0 80 *Myoblasts|*Myotubes|*Cell Differentiation|Myogenin|Myogenesis|RBX1 protein, human|Carrier Proteins|DNA-Binding Proteins|Promoter Regions, Genetic|Repressor Proteins|Cell Line|STAT5B protein, human|STAT5 Transcription Factor|Upregulation|Phosphorylation|Binding Site 26 PDZRN3 29779941 Neuron 2018 PMC6667181 10.1016/j.neuron.2018.04.033 5 0 0 80 Animals|*Neurons|*Cerebral Cortex|Neurogenesis|*Transcription Factors|Neural Stem Cells|*Astrocytes|Neuroglia|Ependymoglial Cells|Cell Migration|*Oligodendroglia|Gene Expression Regulation, Developmental|*Regulatory Sequences, Nucleic Acid|Epigenesis, Genetic 26 PGAP3 30541042 J. Natl. Cancer Inst. 2018 PMC6579744 10.1093/jnci/djy155 3 0 0 17 *Genome-Wide Association Study|*Pancreatic Cancer|Single Nucleotide Polymorphisms|Carcinoma, Pancreatic Ductal|Genetic Predisposition to Disease|Genotype|Risk 39 PGAP3 30345601 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40627 0 0 0 17 Humans|Hyperphosphatasia with Mental Retardation|*Mental Retardation|Phosphorus Metabolism Disorders|Abnormalities, Multiple|*Syndrome|Homozygote|Mutations|PGAP3 protein, human|Receptors, Cell Surface|Pedigree|Phenotype|Mutations, Missense|Cohort Studies|Egypt|Saudi Arabia|Oman|Qatar 39 PGAP3 30217754 Eur J Med Genet 2018 10.1016/j.ejmg.2018.09.002 0 1 0 17 Humans|Hyperphosphatasia with Mental Retardation|*Siblings|Phosphorus Metabolism Disorders|Intellectual Disability|Abnormalities, Multiple|*Mutations|Homozygote|Pedigree|PGAP3 protein, human|Receptors, Cell Surface|Mutation, Missense|Syndrome|Amino Acid Sequence|Alkaline Phosphatase 39 PGAP3 30203254 Mol. Genet. Genomics 2018 10.1007/s00438-018-1488-4 15 0 0 17 *DNA Copy Number Variations|ERBB2 protein, human|Receptor, ErbB-2|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gigantomastia|Breast|Gene Expression Profiling|Databases, Genetic|Cancers|mRNA|Hypertrophy 39 PGAP3 30117066 Breast Cancer Res. Treat. 2018 PMC6208909 10.1007/s10549-018-4920-x 0 0 0 17 Humans|progesterone receptor B|Progesterone Receptor|Receptor, ErbB-2|Receptors, Estrogen|Estrogen Receptor alpha|Immunohistochemistry|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|RNA, Messenger 39 PGAP3 30108155 J. Lipid Res. 2018 PMC6168314 10.1194/jlr.P080218 4 0 0 17 Humans|*Genome-Wide Association Study|*Arabs|*Hypertriglyceridemia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Recessive Gene|Phenotype|European Continental Ancestry Group|Lipids|Kuwait 39 PGAP3 29620724 Genet. Med. 2018 10.1038/gim.2018.50 6 0 0 17 Humans|*Osteochondrodysplasias|*Musculoskeletal Abnormalities|Exome|High-Throughput Nucleotide Sequencing|Pedigree|Phenotype|Mutation|*Phenomic|Cohort Studies 39 PGAP3 29531774 Hum Genome Var 2018 PMC5842148 10.1038/hgv.2018.5 2 0 0 17 Phosphorus Metabolism Disorders|Abnormalities, Multiple|Intellectual Disability|Pedigree|Phenotype|Genetic Predisposition to Disease|Mutation|Receptors, Cell Surface|Syndrome 39 PGAP3 29333270 Clin Transl Immunology 2018 PMC5750453 10.1038/cti.2017.54 19 2 0 17 Humans|*Genome-Wide Association Study|*Asthma|Linkage Disequilibrium|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Quantitative Trait Loci|Genotype|Genetic Variation 39 PGAP3 29310717 Genome Med 2018 PMC5759841 10.1186/s13073-017-0510-5 15 0 0 17 Humans|*Glycosylphosphatidylinositols|*Flow Cytometry|Hyperphosphatasia with Mental Retardation|Phosphorus Metabolism Disorders|Intellectual Disability|Abnormalities, Multiple|Epilepsy|Mutations|Pedigree|Syndrome|Amino Acid Sequence|Alkaline Phosphatase 39 PGAP3 29307657 J. 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Immunol. 2018 PMC6172038 10.1016/j.jaci.2017.12.974 20 2 0 17 Humans|Child|Adult|Child, Preschool|Genome-Wide Association Study|*Asthma|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Genotype|Genetic Predisposition to Disease|Phenotype|Alleles|Lung|DNA Methylation|Neoplasm Proteins|Membrane Proteins|Case-Control Studies|GSDMA protein, human 39 PGDF 30333964 Front Cell Infect Microbiol 2018 PMC6176012 10.3389/fcimb.2018.00350 0 2 0 0 49 PGDF 30156292 Vox Sang. 2018 10.1111/vox.12696 2 0 0 0 amotosalen|Furocoumarins|Blood Buffy Coat|Blood Preservation|Platelets|Ultraviolet Rays 49 pgm5 30025927 Gene 2018 10.1016/j.gene.2018.07.041 15 0 0 35 *RNA, Long Noncoding|*mRNA|*RNA, Circular|*Urinary Bladder Neoplasms|*Transcriptome|*Transcriptome Analysis|*High-Throughput Nucleotide Sequencing|RNA, Micro|Gene Ontology|Gene Regulatory Networks|Computational Biology|Gene Expression Regulation, Neoplastic|Biomarkers|Disease Progression 38 PHACTR1 30570522 Nurs Res 2018 PMC6399059 10.1097/NNR.0000000000000337 0 0 0 73 Humans|Female|*African Americans|Menarche|European Continental Ancestry Group|Menopause|*Genomics|*Phenotype|Genome-Wide Association Study|*Reproduction|Genetic Loci|Polymorphism, Single Nucleotide|Genetic Variation|Risk Factors|Age Factors|*Disease Susceptibility|Cardiovascular Diseases 75 PHACTR1 30517918 Cerebrovasc. Dis. 2018 10.1159/000494704 0 0 0 73 Humans|Young Adult|Genome-Wide Association Study|Vertebral Artery Dissection|Stroke|Carotid Artery, Internal, Dissection|Brain Ischemia|Risk Factors|*Arteries|*Neck 75 PHACTR1 30293016 Atherosclerosis 2018 10.1016/j.atherosclerosis.2018.08.041 1 12 0 73 *Endothelial Cells|*Coronary Vessels|*Actin|Genome-Wide Association Study|*Inflammation|NF-kappa B|Transcription Factor RelA|Coronary Artery Disease|*Oxidative Stress|*Phosphoric Monoester Hydrolases|Atherosclerosis|Tumor Necrosis Factor-alpha|Phosphorylation|Myocardial Infarction 75 PHACTR1 30285053 JAMA Neurol 2018 10.1001/jamaneurol.2018.2848 1 0 0 73 75 phlda2 30553874 Front Neuroendocrinol 2018 10.1016/j.yfrne.2018.12.003 2 0 0 478 Humans|Pregnancy|Female|Animals|Genomic Imprinting|Placenta|Mammals|Gene Expression Regulation, Developmental|Genome|Nuclear Proteins|Maternal Behavior 89 phlda2 30207029 Cancer Sci. 2018 PMC6215895 10.1111/cas.13796 3 3 0 478 *Proto-Oncogene Proteins c-akt|Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|RNA, Messenger 89 phlda2 30063711 PLoS Biol. 2018 PMC6067684 10.1371/journal.pbio.2006599 10 1 0 478 Pregnancy|Humans|Male|Female|Mice|Animals|Placenta|*Mammals|Genomic Imprinting|Fetal Growth Retardation|Nuclear Proteins|Gene Dosage|Maternal Behavior|Alleles|Phenotype|Gene Expression|Hormones|*Fathers 89 phlda2 30051747 Epigenetics 2018 PMC6224220 10.1080/15592294.2018.1503489 1 0 0 478 Humans|Female|Sheep|Animals|Genomic Imprinting|*Fetuses|IGF2 protein, human|IGF-2|Alleles|*Genomics|DNA Methylation|*Maternal Nutritional Physiological Phenomena|Parthenogenesis|DNA|Gene Expression Regulation, Developmental|RNA, Long Noncoding|DIRAS3 protein, human|rho GTP-Binding Proteins|CasD1 protein, human|Acetyltransferases|COPG2 protein, human|Coatomer Protein 89 phlda2 29906516 Toxicol In Vitro 2018 10.1016/j.tiv.2018.06.011 1 0 0 478 Humans|*Nanotubes, Carbon|*Astrocytes|HLA-DRA|Genes, MHC Class II|Gene Expression|lamin B1|Lamin Type B|Genes, MHC Class I|Apoptosis|Major Histocompatibility Complex|HLA-F antigens|Histocompatibility Antigens Class I|Downregulation|LILRB1 protein, human|Antigens, CD|Leukocyte Immunoglobulin-like Receptor B1|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1 89 PHLDB1 29348417 Sci Rep 2018 PMC5773524 10.1038/s41598-018-19447-2 3 17 0 51 *Podosomes|*Cell Movement|Cell Adhesion|Extracellular Matrix|Actins|Cell Line, Tumor 41 PHOX2A 30315878 Neuroscience 2018 PMC6246807 10.1016/j.neuroscience.2018.09.038 1 0 0 119 Humans|Animals|Rats|Adult|*Locus Coeruleus|*Corticosterone|*Depressive Disorder, Major|NBPhox protein|*Transcription Factors|Homeodomain Proteins|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Norepinephrine|Dopamine beta-Hydroxylase|Norepinephrine Plasma Membrane Transport Proteins|Rats, Inbred F344|mRNA|Neurons|Brain 188 PHOX2A 29729503 Stem Cell Res 2018 10.1016/j.scr.2018.04.012 2 0 0 119 Humans|Human Induced Pluripotent Stem Cells|*Motor Neurons|*Pluripotent Stem Cells|Amyotrophic Lateral Sclerosis|Cell Differentiation|*Neurons, Efferent|*Skull 188 PHPT1 29787434 Health Phys 2018 PMC5967635 10.1097/HP.0000000000000844 2 0 0 62 Humans|*Biomarkers|Dose-Response Relationship, Radiation|Cancer|Gene Expression Regulation, Neoplastic|Radiation Exposure|Transcription Factors|Ionizing Radiation|Curcumin|Lipopolysaccharides 42 PHPT1 29630837 Biochemistry 2018 10.1021/acs.biochem.8b00278 0 0 0 62 Animals|*Histidine|6,8-difluoro-4-methylumbelliferyl phosphate|Hymecromone|Phosphoric Monoester Hydrolases|Fluorogenic Substrate|Kinetics|*Biochemical Phenomena|*Biological Assay|Phosphorylation 42 PHPT1 29474504 PLoS ONE 2018 PMC5825084 10.1371/journal.pone.0193412 4 2 0 62 Female|Humans|Leukocytes, Mononuclear|*Radiation Exposure|Radiometry|Dose-Response Relationship, Radiation|Radiation Injuries|Leukocytes|*Biomarkers|Tumor|Chromosomes|Triage 42 PHPT1 29440278 Diabetes 2018 PMC5909995 10.2337/db17-1433 2 2 0 62 Congenital Hyperinsulinism|KATP Channels|Insulin-Secreting Cells|Insulin|AMP-Activated Protein Kinases|Leptin 42 PILRA 30388101 PLoS Genet. 2018 PMC6235402 10.1371/journal.pgen.1007427 4 0 0 23 Humans|*Alzheimer Disease|Receptors, Immunologic|Membrane Glycoproteins|glycoprotein B, Simplexvirus|Viral Envelope Proteins|Genetic Predisposition to Disease|Microglia|Ligands|Herpes Simplex Virus 1|Sialic Acid|Mutation, Missense|*Biophysical Phenomena|Immunoglobulins|PILRA protein, human 38 PIM3 30568945 World J Clin Cases 2018 PMC6288502 10.12998/wjcc.v6.i15.908 0 0 0 271 Humans|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn Disease|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Phenotype|Case-Control Studies 172 PIN4 30567987 J. Virol. 2018 PMC6401437 10.1128/JVI.01840-18 6 4 0 144 *B virus, Hepatitis|*Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4|*Virion|DNA, Circular|Hepatitis B|DNA, Viral|*Upregulation|Virus Replication|Trans-Activators|Hep G2 Cells|*Transcriptional Activation 96 PIN4 30537612 J. Plant Physiol. 2018 10.1016/j.jplph.2018.11.004 1 0 0 144 *Seedlings|Phylogeny|Cytokinins|Arabidopsis|Arabidopsis Proteins|Meristem|Plant Growth Regulators|Plant Shoots|Gene Expression Regulation, Plant|Indoleacetic Acids|Genes, Plant|Plant Roots|Transcription Factors|Plants, Genetically Modified|Gene Expression Profiling|CUC1 protein, Arabidopsis 96 PIN4 30415491 J Integr Plant Biol 2018 10.1111/jipb.12735 1 3 0 144 *Arabidopsis|*Factor 8|indoleacetic acid|*Auxin|Arabidopsis Proteins|Meristem|Plant Roots|Gene Expression Regulation, Plant|Transcription Factor|*Organogenesis, Plant|*Promoter Regions, Genetic|Plants, Genetically Modified|YUCCA2 protein, Arabidopsis|Mixed Function Oxygenases 96 PIN4 30314361 Biomolecules 2018 PMC6316532 10.3390/biom8040112 2 0 0 144 cyclophilin B|Cyclophilins|NIMA-Interacting Peptidylprolyl Isomerase|Protein Conformation|Tacrolimus Binding Proteins|Substrate Specificity|Phosphorylation|*Brain Cancer 96 PIN4 30096758 Int J Mol Sci 2018 PMC6121450 10.3390/ijms19082319 2 35 0 144 Peptidylprolyl Isomerase|NIMA-Interacting Peptidylprolyl Isomerase|Phosphorylation|Alzheimer Disease|Protein Binding|Diabetes Mellitus 96 PIN4 29981254 Plant Cell Environ. 2018 10.1111/pce.13402 2 2 0 144 *Arabidopsis|*Flavonoids|Arabidopsis Proteins|Auxin|Gene Expression Regulation, Plant|Seed|Transcription Factors|Biological Transport|Acids, Fatty|Phenotype 96 PIN4 29901570 Am. 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Pathol. 2018 10.1097/PAS.0000000000001108 0 0 0 144 Male|Humans|Middle Aged|Aged|Aged, 80 and over|Neoplasm Recurrence, Local|*Adenocarcinoma|Prostate-Specific Antigen|Urethral Neoplasms|Prostate|Prostatic Neoplasms|Immunohistochemistry|*Exocrine Glands|Neoplasm Grading|Biomarkers, Tumor|*Urethra|*Uterine Cervical Neoplasms|SATB2 protein, human|Transcription Factors|Matrix Attachment Region Binding Proteins 96 PIN4 29717021 Plant Physiol. 2018 PMC6001322 10.1104/pp.17.01691 12 3 0 144 *Auxin|*Cytokinins|Arabidopsis|Arabidopsis Proteins|Gene Expression Regulation, Plant|Plant Shoots|Plant Growth Regulators|Transcription Factors|Genes, Plant|Plant Roots|Plants, Genetically Modified|Phenotype|Membrane Transport Proteins|Biological Transport|Signal Transduction 96 PIN4 29671782 Int J Mol Sci 2018 PMC5979548 10.3390/ijms19041238 7 5 0 144 *Auxin|Gravitropism|Arabidopsis Proteins|Arabidopsis|Plant Roots|Gene Expression Regulation, Plant|Gravity Sensing|Signal Transduction|Gravity|PIN7 protein, Arabidopsis 96 PIN4 29607503 Physiol Plant 2018 10.1111/ppl.12709 2 1 0 144 *Coffea|*Ectopic Gene Expression|Auxin|Gene Expression Regulation, Plant|Plant Proteins|*Embryogenesis|Seeds|Plant Leaves|Gene Expression Regulation, Developmental|Amino Acid Sequence 96 PIN4 29459728 Sci Rep 2018 PMC5818486 10.1038/s41598-018-21679-1 3 12 0 144 *Lycopersicon esculentum|*Plant Leaves|Gene Expression Regulation, Plant|Plant Proteins|Plant Growth Regulators|Gibberellins|Plants, Transgenic|Transcription Factors|RNAi|Phenotype 96 PIN4 29330265 Cancer Discov 2018 10.1158/2159-8290.CD-RW2018-008 1 1 0 144 *Phosphorylation|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|*Mitochondria|Oncogene Proteins, Fusion|Microtubule-Associated Proteins|Cell Line, Tumor|*Respiration 96 PIN4 29323298 Nature 2018 PMC5771419 10.1038/nature25171 16 19 0 144 Humans|FGFR3 protein, human|Receptor, Fibroblast Growth Factor, Type 3|Glioblastoma|Brain Neoplasms|Oncogene Proteins, Fusion|Gene Fusions|Oncogene Fusions|Chromosomal Translocations|Cell Line, Tumor|Xenograft Model Antitumor Assays|Oxidative Phosphorylation|Cell Transformation, Neoplastic|Microtubule-Associated Proteins|Signal Transduction|TACC3 protein, human 96 PIWIL3 29486732 BMC Genet. 2018 PMC5830072 10.1186/s12863-018-0600-4 4 0 0 21 Cattle|Male|Animals|*Conception|Fertility|Dairying|Breeding|Single Nucleotide Polymorphism|Genotype|Genome|Phenotype|Genomics|Biomarkers 24 PIWIL3 29470513 PLoS ONE 2018 PMC5823368 10.1371/journal.pone.0190698 10 7 0 21 Pregnancy|Humans|Female|*DNA Methylation|*Diabetes, Gestational|*Placenta|CpG Islands|Epigenesis, Genetic|*Gene Expression|Prenatal Exposure Delayed Effects|Diabetes Mellitus, Type 2|Genome 24 PIWIL3 29464001 Theranostics 2018 PMC5817112 10.7150/thno.21740 20 60 0 21 24 PLAC1 30267394 Z Geburtshilfe Neonatol 2018 10.1055/a-0743-7403 0 0 0 109 Infant, Newborn|Pregnancy|Female|Humans|*Fetal Growth Retardation|PLAC1 protein, human|Case-Control Studies|Pregnancy Proteins|Pre-Eclampsia|Area Under Curve|*Infant, Small for Gestational Age|Gestational Age|Specificity|Pregnant Women|Biomarkers 91 PLAC1 29723063 FASEB J. 2018 10.1096/fj.201700922RR 3 2 0 109 Humans|Pregnancy|Female|Mice|Animals|*Furin|Meiosis|Oocytes|Oogenesis|Fertilization|*Placenta|Cell Nucleus|Aneuploidy|Cytoplasm|PLAC1 protein, human|Pregnancy Proteins 91 PLAC1 29704427 Mol Oncol 2018 PMC6068355 10.1002/1878-0261.12311 3 34 0 109 Humans|Male|PLAC1 protein, human|*Furin|*Testis|PTEN protein, human|*PTEN Phosphohydrolase|Pregnancy Proteins|*Signal Transduction|Receptor, Notch1|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Line, Tumor|Lymphatic Metastasis|Cell Movement 91 PLAC1 29664550 Ginekol. Pol. 2018 10.5603/GP.a2018.0025 0 0 0 109 Pregnancy|Female|Humans|*Pre-Eclampsia|Placenta Growth Factor|Pregnancy Proteins|Vascular Endothelial Growth Factor Receptor-1|ROC Curve|TYRP1 protein, human|*Membrane Glycoproteins|Gestational Age|Case-Control Studies|Biomarkers|PLAC1 protein, human 91 PLAC1 29632317 Sci Rep 2018 PMC5890253 10.1038/s41598-018-24022-w 2 11 0 109 Humans|Pregnancy|Male|Female|Adult|Mice|Animals|PLAC1 protein, human|*SCID Mice|Pregnancy Proteins|*Cell Transformation, Neoplastic|Trophoblast|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|CXCL1 protein, human|Chemokine CXCL1|Gene Expression Profiling|Placenta|Receptors, Interleukin-8B|*Immune Tolerance|Tumor Microenvironment|PLAC1 protein, mouse 91 PLAC1 29556312 Oncol Lett 2018 PMC5844056 10.3892/ol.2018.8075 2 3 0 109 Humans|Male|PLAC1 protein, human|Pregnancy Proteins|HLA-A2 Antigen|T-Lymphocytes, Cytotoxic|Adoptive Immunotherapy|CD8-Positive T-Lymphocytes|Epitopes, T-Lymphocyte|Antigens, Neoplasm|Lymphocyte Activation|Cell Line, Tumor|Immunotherapy|Receptors, Antigen, T-Cell 91 PLAC1 29532882 Mol Med Rep 2018 PMC5928614 10.3892/mmr.2018.8721 2 2 0 109 Infant, Newborn|Humans|Female|Pregnancy|*Fetal Growth Restriction|*Protein A|5'-palmitoyl cytarabine|Placenta|*Infant, Small for Gestational Age|Pregnancy Associated Plasma Protein A|Pregnancy Proteins|*Blood Proteins|Birth Weight 91 PLAC1 29432428 PLoS ONE 2018 PMC5809008 10.1371/journal.pone.0192106 4 0 0 109 Humans|Female|Pregnancy|PLAC1 protein, human|Neoplasm Recurrence, Local|Pregnancy Proteins|Ductal Carcinoma In Situ|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Trophoblast 91 PLAC4 30544028 Eur. 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Fatty Acids 2018 10.1016/j.plefa.2018.07.013 0 2 0 44 Pregnancy|Infant, Newborn|Female|Child|Humans|Child, Preschool|*Gestational Age|*Infant, Small for Gestational Age|Birth Weight|n 3 PUFA|Fetal Growth|*Parturition|Allele|*Phenotype|Genotype|Polymorphism, Single Nucleotide|Fetal Growth Retardation|Insulin Resistance|*Impulsivity|PLIN4 protein, human|Perilipin-4 52 PLIN4 29967574 Front Neurosci 2018 PMC6015897 10.3389/fnins.2018.00397 4 1 0 44 Mice|Animals|*Parkinson Disease|*Mitophagy|*1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|*Lipid Droplets|Dopaminergic Neurons|Mesencephalon|*Disease Models, Animal|Tyrosine Hydroxylase|Upregulation 52 PLIN4 29626194 Nat Commun 2018 PMC5889406 10.1038/s41467-018-03717-8 12 13 0 44 Humans|*Perilipin|*Lipid Droplets|Phospholipids|Lipid Bilayers|Protein Binding|Hydrophobicity|Protein Transport|Perilipin-4 52 PLIN4 29409445 BMC Genomics 2018 PMC5801776 10.1186/s12864-018-4509-0 2 16 0 44 Pregnancy|Humans|Female|Animals|Sheep|*Transcriptome|*Tissues, Fetal|DNA Methylation|Epigenesis, Genetic|*Diet|*Prenatal Care|Epigenetic|*Tissues, Muscle|Phenotypes 52 PLIN4 29361938 BMC Complement Altern Med 2018 PMC5781311 10.1186/s12906-018-2099-7 2 5 0 44 *Weight Loss|*Garcinia cambogia|(1-6)-alpha-glucomannan|Quality of Life|*Obesity|*Mannans|Overweight|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Body Mass Index|Receptors, Adrenergic, beta-3|Alleles|Polymorphism, Single Nucleotide|Genotype 52 PLXDC2 30326957 BMC Res Notes 2018 PMC6192173 10.1186/s13104-018-3848-x 1 0 0 107 plexin|Saudi Arabia|*Glaucoma, Primary Open Angle|*Nerve Tissue Proteins|*Cohort Studies|*Cell Adhesion Molecules|Gene Frequency|Intraocular Pressure|Genotype|Alleles|Case-Control Studies|Polymorphism, Single Nucleotide|Receptors, Cell Surface 29 PLXDC2 29928353 Oncol Lett 2018 PMC6004651 10.3892/ol.2018.8600 2 4 0 107 Humans|Female|*Paclitaxel|*Carcinoma, Ovarian Epithelial|*Proteomics|*Ovarian Neoplasms|Drug Resistance, Neoplasm|Cisplatin|Cell Line, Tumor|Antineoplastic Combined Chemotherapy Protocols|Blotting, Western 29 PLXDC2 29378261 Protein Expr. Purif. 2018 10.1016/j.pep.2018.01.011 0 0 0 107 29 PM20D1 29967167 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6055169 10.1073/pnas.1803389115 7 8 0 15 27 PM20D1 29736028 Nat. Med. 2018 10.1038/s41591-018-0013-y 9 0 0 15 *Alzheimer Disease|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Quantitative Trait Loci|Brain|*Phenotype 27 PM20D1 29533650 J. Med. Chem. 2018 PMC6335027 10.1021/acs.jmedchem.8b00029 4 0 0 15 Animals|Mice|*Hydrolysis|*Mitochondria|Energy Expenditure|Uncoupling Protein 1|*Amino Acids|Oxygen Consumption|Homeostasis|*Respiration|*Central Nervous System Stimulants|PM20D1 protein, mouse|Amidohydrolases 27 POTEE 30459449 Sci Rep 2018 PMC6244393 10.1038/s41598-018-35567-1 4 0 0 39 Male|Female|Humans|Phylogeny|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cystadenocarcinoma, Serous|Neoplasms, Glandular and Epithelial|Fallopian Tubes|DNA Methylation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Promoter Regions, Genetic|Proteins 20 POTEE 30420269 Cell. Immunol. 2018 10.1016/j.cellimm.2018.10.010 2 1 0 39 Male|Female|*mTORC2|*Macrophages|*Immunoreceptor Tyrosine-Based Activation Motif|Myeloproliferative Syndrome, Transient|*Leukemoid Reaction|*Tamoxifen|*Down Syndrome|Monocytes|Signal Transduction|Immunity, Innate|T Cells|Cancers|*Myopathies, Structural, Congenital|Cell Survival 20 POTEE 30391463 Life Sci. 2018 10.1016/j.lfs.2018.10.068 3 2 0 39 Humans|*HIV-1|*mTORC2|nef Gene Products, Human Immunodeficiency Virus|*Macrophage|*Signal Transduction|HIV Infections|Host-Pathogen Interactions|Cell Movement|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 20 pou2f3 30379593 Annu. Rev. 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Sci. 2018 10.1016/j.rvsc.2018.07.006 0 0 0 144 Horses|Animals|*DNA Methylation|*B-DNA|Bovine papillomavirus 1|Skin Neoplasms|Horse Diseases|*Genes, cdc|Skin|Promoter Regions, Genetic|Epigenetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 50 pou2f3 30022162 Nature 2018 10.1038/s41586-018-0346-1 20 0 0 144 Mice|Animals|*Cells, Epithelial|Cell Differentiation|Transcription Factors|*B-Lymphocytes|Mice, Inbred C57BL|Gene Expression Profiling 50 pou2f3 29967289 Genes Dev. 2018 PMC6075039 10.1101/gad.316943.118 3 0 0 144 Small Cell Lung Carcinoma|*Pulmonary Cancer|*Carcinoma, Neuroendocrine|Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|Oncogenes|Gene Expression Regulation, Neoplastic|Lung|Cell Line, Tumor 50 pou2f3 29945888 Genes Dev. 2018 PMC6075037 10.1101/gad.314815.118 17 0 0 144 Humans|*Small Cell Lung Carcinoma|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Lung Neoplasms|Transcription Factor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Neuroendocrine Cells|Receptor, IGF Type 1|Nerve Tissue Proteins|POU2F3 protein, human|Octamer Transcription Factors 50 pou2f3 29604293 Gastroenterology 2018 PMC6035075 10.1053/j.gastro.2018.03.041 19 9 0 144 IL17A protein, human|*Interleukin-17|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Carcinoma in Situ|Pancreas|Signal Transduction|Cell Transformation, Neoplastic|*B-Lymphocytes|Chronic Pancreatitis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Neoplastic Stem Cells 50 pou2f3 29536689 Zhongguo Gu Shang 2018 10.3969/j.issn.1003-0034.2018.02.014 0 0 0 144 *Transcriptome|*Osteoarthritis|Gene Expression Profiling|Gene Regulatory Networks|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation|Synovial Membrane|Transcription Factors|*Complement Factor B|*Bone|3'-(1-butylphosphoryl)adenosine 50 pou2f3 29530408 Neuropeptides 2018 10.1016/j.npep.2018.02.007 1 2 0 144 Mice|Animals|*Neuropeptide Y|Sensory Neurons, Olfactory|*Smell|Olfactory Mucosa|*Cell Differentiation|Gene Expression Regulation|TRPM Cation Channels 50 POU3F1 30446350 Mol. Genet. Metab. 2018 10.1016/j.ymgme.2018.10.004 4 0 0 285 Humans|*Resveratrol|*Canavan Disease|*RNA|*High-Throughput Nucleotide Sequencing|Sirtuin 1|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Stilbenes|Mitochondria|Transcription Factors|Lipid Metabolism|Gene Expression Regulation|Oxidation-Reduction|Mitochondrial Biogenesis|Fibroblasts|Metabolic Diseases 138 POU3F1 29877572 Int. J. Dev. Biol. 2018 10.1387/ijdb.170260RL 0 0 0 285 Animals|*Xenopus laevis|*Transcription Factor|Phylogeny|*Embryonic Development|Xenopus Proteins|Embryo, Nonmammalian|Ectoderm|Gene Expression Regulation, Developmental|In Situ Hybridization|Zebrafish|*Kidney|Mesoderm|Nervous System 138 POU3F3 30474879 J. Cell. Biochem. 2018 10.1002/jcb.28101 1 5 0 131 Humans|Male|*RNA, Long Noncoding|*Prostate|*Cell Proliferation|*Upregulation|ROCK1 protein, human|*rho-Associated Kinases|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|POU Domain Factors|Cell Movement|Cell Line, Tumor|*Prostatic Neoplasms|POU3F3 protein, human 67 POU3F3 30329130 Nucleic Acids Res. 2018 PMC6326801 10.1093/nar/gky953 4 4 0 131 Mice|Animals|*Neurons|Neurogenesis|Transcription Factors|DNA-Binding Proteins|Cerebral Cortex|Cell Differentiation|Chromatin|Repressor Proteins|Histones|Histone-Lysine N-Methyltransferase|Nerve Tissue Proteins|Transcription, Genetic|Gene Expression Regulation, Developmental|Methylation|Cell Cycle|Cell Proliferation|Dot1l protein, mouse|Cenpj protein, mouse 67 POU3F3 29906746 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.06.006 5 3 0 131 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Cell Proliferation|RNA, Long Noncoding|Cell Movement|Gene Expression Regulation, Neoplastic|Up-Regulation|Cell Line, Tumor|Glioma|Hep G2 Cells|RNA Interference|POU Domain Factors|mRNA|Colorectal Cancer|Oncogenesis|*Neoplastic Processes|Esophageal Cancer|POU3F3 protein, human 67 POU3F3 29877572 Int. J. Dev. Biol. 2018 10.1387/ijdb.170260RL 0 0 0 131 Animals|*Xenopus laevis|*Transcription Factor|Phylogeny|*Embryonic Development|Xenopus Proteins|Embryo, Nonmammalian|Ectoderm|Gene Expression Regulation, Developmental|In Situ Hybridization|Zebrafish|*Kidney|Mesoderm|Nervous System 67 POU3F3 29571612 Dev. Biol. 2018 PMC6148416 10.1016/j.ydbio.2018.02.012 4 4 0 131 Animals|Andersen-Tawil Syndrome|Kir2.1 channel|Potassium Channels, Inwardly Rectifying|*Signal Transduction|Embryo, Mammalian|*Mammals|Mutations|Face|*Gene Expression Regulation 67 POU3F3 29395907 Neuron 2018 10.1016/j.neuron.2017.12.045 19 2 0 131 Animals|Mice|*Neurons|Neurogenesis|Neural Stem Cells|Ependymoglial Cells|RNA Binding Protein|*Mammals|Cerebral Cortex|mRNA|Pum2 protein, mouse 67 POU3F4 30478432 Sci Rep 2018 PMC6255903 10.1038/s41598-018-35587-x 2 0 0 75 Mice|Animals|Female|Pregnancy|*B-DNA|*DNA Methylation|*Embryonic Development|Ear, Inner|*Hearing|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Hair Cells, Auditory|Nerve Tissue Proteins|Cell Differentiation|Regulatory Regions|Bach2 protein, mouse|Basic-Leucine Zipper Transcription Factors 154 POU3F4 30289920 PLoS ONE 2018 PMC6173455 10.1371/journal.pone.0205298 1 0 0 75 Humans|*Translocation, Genetic|Intellectual Disability|Phenotype|Speech Delay|Base Sequence|Dominant Gene|Sequencing, Whole Genome|POU3F4 protein, human|POU Domain Factors 154 POU3F4 30176854 BMC Med. Genet. 2018 PMC6122742 10.1186/s12881-018-0630-9 0 1 0 75 Humans|*Deafness|Progressive hearing loss stapes fixation|Hearing Loss, Sensorineural|*Hearing Loss|Hearing Loss, Conductive|Genetic Diseases, X-Linked|*Mutations|POU Domain Factors|Pedigree|*Chinese|Genes, X-Linked|POU3F4 protein, human 154 POU3F4 30065609 Curr. Genomics 2018 PMC6030855 10.2174/1389202919666171218163046 1 0 0 75 Deafness, X-Linked 5|Genetic Diseases, X-Linked|Progressive hearing loss stapes fixation|*Hearing Loss, Sensorineural|Deafness, X-Linked 4|Deafness, X-Linked 1|Hearing Loss, Conductive|Hearing Loss|Deafness|Phenotype|Pedigree|Genotype|Genes, X-Linked|Mutation|Chromosome Deletion|Vestibulocochlear Nerve Diseases|Cochlear Nerve 154 POU3F4 29986705 BMC Med Genomics 2018 PMC6038346 10.1186/s12920-018-0375-5 10 4 0 75 Humans|*Hearing Loss, Sensorineural|*Deafness|Sequencing, Next-Generation|DNA Mutational Analysis|Connexins|Exome|*Genomics|Genetic Testing|Mutation|*Syndromes 154 POU3F4 29921047 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 10.13201/j.issn.1001-1781.2018.11.003 0 0 0 75 154 POU3F4 29877572 Int. J. Dev. Biol. 2018 10.1387/ijdb.170260RL 0 0 0 75 Animals|*Xenopus laevis|*Transcription Factor|Phylogeny|*Embryonic Development|Xenopus Proteins|Embryo, Nonmammalian|Ectoderm|Gene Expression Regulation, Developmental|In Situ Hybridization|Zebrafish|*Kidney|Mesoderm|Nervous System 154 POU3F4 29749639 J. Neurochem. 2018 10.1111/jnc.14456 2 3 0 75 Mice|Animals|*Homeodomain Proteins|*Neurogenesis|pros protein, Drosophila|*Nerve Tissue Proteins|*Homeobox|Neural Stem Cells|*Nuclear Proteins|*Drosophila Proteins|Neurons|SOXC Transcription Factors|Neural Tube|HNF1A protein, human|*Hepatocyte Nuclear Factor 1-alpha|Gene Expression Regulation, Developmental|*Vertebrate|Tumor Suppressor Proteins|Chromatin Immunoprecipitation 154 POU6F1 30444277 Dev. Dyn. 2018 PMC6340724 10.1002/dvdy.2 0 1 0 30 Animals|Humans|*Zebrafish|*Heart|Zebrafish Proteins|BMP4 protein, human|*Bone Morphogenetic Protein 4|Atrioventricular Septal Defect|*Heart Septal Defects|Animals, Genetically Modified|Gene Expression Regulation, Developmental|T-Box Domain Proteins|Heart Defects, Congenital|Wnt Signaling Pathway 34 POU6F1 29856744 PLoS ONE 2018 PMC5983438 10.1371/journal.pone.0197092 1 5 0 30 Animals|Rats|*Stroke|*Proto-Oncogene Protein c-ets-1|*Brain Ischemia|NRG1 protein, human|*Neuregulin-1|*Transcriptome|Middle Cerebral Artery Occlusion|*Transcriptome Analysis|*Binding Sites|Gene Expression Regulation|Neuroprotective Agents|Neuroprotection|*Promoter Regions, Genetic|Disease Models, Animal|Signal Transduction|Oncogenes 34 POU6F1 29481668 Rheumatology (Oxford) 2018 10.1093/rheumatology/kex517 7 0 0 30 Humans|*Spondylitis, Ankylosing|*Synovial Fluid|*Receptors, Antigen, T-Cell, alpha-beta|*CD8-Positive T-Lymphocytes 34 POU6F1 29305536 J. Neurosci. 2018 PMC5815346 10.1523/JNEUROSCI.1641-17.2017 2 3 0 30 Animals|Mice|CRF receptor type 1|Receptors, Corticotropin-Releasing Hormone|Corticotropin-Releasing Hormone|Interneurons|Neurons|*Neuropeptide|Olfactory Bulb|Hippocampus|*Brain|Signal Transduction 34 PPP1R3A 29948331 Mol. Genet. Genomics 2018 10.1007/s00438-018-1453-2 3 0 0 909 Humans|*Diabetes Mellitus, Type 2|*Whole Exome Sequencing|Case-Control Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Insulin Resistance|Genotype|Alleles|Population Groups|Mexico|PPP1R3A protein, human|Phosphoprotein Phosphatases 40 PPP1R3A 29731991 Oncotarget 2018 PMC5929434 10.18632/oncotarget.24924 2 0 0 909 Humans|*Gene Amplification|*High-Throughput Nucleotide Sequencing|Neoplasm Recurrence, Local|*Liposarcoma, Well Differentiated|*Neoplasms, Adipose Tissue|*Mutations|Soft Tissue Neoplasms|Proto-Oncogene Proteins c-mdm2|Immunohistochemistry|Soft Tissue Sarcoma|In Situ Hybridization, Fluorescence|Cyclin-Dependent Kinase 4|Biomarkers, Tumor 40 PRB2 30144656 Stem Cell Res 2018 10.1016/j.scr.2018.07.012 1 0 0 68 Humans|Spastic ataxia Charlevoix-Saguenay type|*Spinocerebellar Ataxias|*Muscle Spasticity|*Mutation|*Induced Pluripotent Stem Cells|Heat-Shock Proteins 207 PRB2 30064219 J. Proteome Res. 2018 10.1021/acs.jproteome.8b00444 1 0 0 68 Adult|Humans|*Salivary Proline-Rich Proteins|*Proline|*Mass Spectrometry|Salivary Proteins|Chromatography, Liquid|Amino Acid Sequence|Post-Translational Modifications|Proteomics|BPIFA4P protein, human|*Neoplasm Proteins|*Membrane Proteins|Chromatography, High Pressure Liquid|Saliva 207 PRB2 30058282 J Tissue Eng Regen Med 2018 10.1002/term.2743 8 0 0 68 Humans|Female|*Mesenchymal Stem Cells|*TGFbeta|*CD4-Positive T-Lymphocytes|*Extracellular Vesicles|*Endometrium|Cell Differentiation|Multipotent Stem Cells|Immunomodulation|Lymphocyte Activation|Exosomes|Cells, Cultured 207 PRB2 30019781 Chemistry 2018 10.1002/chem.201802875 4 0 0 68 *Rhodamine|*Fluorescent Dyes|*Phosphorus|Optical Imaging|Fluorescence|Silicon|Solubility 207 PRB2 29910519 Stud. Mycol. 2018 PMC6002337 10.1016/j.simyco.2018.02.001 3 0 0 68 207 PRB2 29751147 Arch. Oral Biol. 2018 10.1016/j.archoralbio.2018.04.012 2 0 0 68 *Genetic Predisposition to Disease|*Genotype|*Periodontal Disease|Polymorphism, Single Nucleotide|Periodontitis|Case-Control Studies 207 PRB2 29499498 Stem Cell Res 2018 10.1016/j.scr.2018.02.011 4 0 0 68 Male|Humans|*mRNA|*Induced Pluripotent Stem Cells|Cellular Reprogramming|Cell Line|Cell Culture Techniques|Octamer Transcription Factor-3|Fibroblasts|Foreskin|Cell Differentiation|Karyotyping 207 PRB2 29453128 Stem Cell Res 2018 10.1016/j.scr.2018.01.004 2 0 0 68 Humans|*Induced Pluripotent Stem Cells|Cellular Reprogramming|Cell Line|*Mutation|*Hydrophthalmos|Cell Culture Techniques|Cell Differentiation|*Retinal Degeneration|CYP1B1 protein, human|Cytochrome P-450 CYP1B1 207 PRDM2 30458291 Gene 2018 10.1016/j.gene.2018.11.046 4 1 0 177 Male|Animals|Mice|*Histones|*Methylation|Epigenesis, Genetic|Set2 protein, human|Histone-Lysine N-Methyltransferase|SETD1B protein, human|NSD2 protein, human|KMT2A protein, human|KDM1A protein, human|Histone Demethylases|*Cyprinodontiformes|*Self-Fertilizations|PRDM2 protein, human|KDM5C protein, human|Embryonic Development|*Killifishes|*Reproduction|KMT2D protein, human 156 PRDM2 30347759 Int J Mol Sci 2018 PMC6214140 10.3390/ijms19103250 4 7 0 177 *PR-SET Domains|*Malignancies|*Genome|Transcriptomes|Genomics|Zinc Finger Motifs|Transcription Factors|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Isoforms 156 PRDM2 30293369 Zhonghua Shao Shang Za Zhi 2018 10.3760/cma.j.issn.1009-2587.2018.09.015 0 0 0 177 156 PRDM2 30120715 Endocr. Pathol. 2018 10.1007/s12022-018-9543-6 2 0 0 177 Humans|*Whole Exome Sequencing|Phosphatidylinositol 3-Kinases|Thyroid cancer, medullary|*Carcinoma, Neuroendocrine|*Thyroid Cancer|Carcinoma, Medullary|Proto-Oncogene Proteins c-ret|Exome|*Asian Continental Ancestry Group|Illumina Sequencing|Mutations|MicroRNAs|Signal Transduction|Taiwan|SCRN1 protein, human|Nerve Tissue Proteins|KLHL25 protein, human|Carrier Proteins 156 PRDM2 29883756 Biochim Biophys Acta Gene Regul Mech 2018 10.1016/j.bbagrm.2018.06.002 3 0 0 177 Humans|PRDM2 protein, human|*Transcription Factors|*Histone-Lysine N-Methyltransferase|Zinc Finger|Retinoblastoma Protein|Tumor Cells, Cultured|Oestradiol 156 PRDM2 29872311 Onco Targets Ther 2018 PMC5973400 10.2147/OTT.S156775 4 4 0 177 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Promoter Regions, Genetic|DNA Methylation|DNA-Binding Proteins|Epigenesis, Genetic|Transcription Factors|Gene Expression Regulation, Neoplastic|Decitabine|Azacitidine|Cell Line, Tumor 156 PRDM2 29575614 Basic Clin. Pharmacol. Toxicol. 2018 10.1111/bcpt.13008 3 0 0 177 Humans|Female|Mice|Animals|*Uterine Cervical Neoplasms|Mice, Nude|DNA-Binding Proteins|*HeLa Cells|Transcription Factors|Nuclear Proteins|Histone-Lysine N-Methyltransferase|*Apoptosis|*DNA Damage|Genes, Tumor Suppressor|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|RNA, Messenger 156 PRDM2 29465369 Clin. Exp. Rheumatol. 2018 1 31 0 177 *Histone-Lysine Methyltransferase|*Transcriptome|*Rheumatoid Arthritis|Synovial Membrane|*Fibroblasts|Osteoarthritis|Cells, Cultured|Methylation 156 PRDM2 29367689 Sci Rep 2018 PMC5784169 10.1038/s41598-018-19943-5 2 11 0 177 Humans|AKT3 protein, human|*Proto-Oncogene Proteins c-akt|HEK293 Cells|*Genes, Tumor Suppressor|DNA-Binding Proteins|Transcription Factors|Nuclear Proteins|Histone-Lysine N-Methyltransferase|Promoter Regions, Genetic|DNA Methylation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Chromatin Immunoprecipitation|Down-Regulation|RNA, Messenger|Transcription, Genetic 156 PRDM2 29352181 Blood Cancer J 2018 PMC5802577 10.1038/s41408-017-0036-5 9 12 0 177 Humans|*Leukemia, Prolymphocytic, T-Cell|*SAM Domain and HD Domain-Containing Protein 1|Epigenesis, Genetic|DNA Mutational Analysis|Mutations|Base Sequence|Exome|Genes, Tumor Suppressor|Ataxia Telangiectasia Mutated Proteins|PRDM2 protein, human|DNA-Binding Proteins|Chromosomal Translocations|*Databases, Genetic|Nuclear Proteins|Histone-Lysine N-Methyltransferase|Transcription Factors|SAMHD1 protein, human|PARP10 protein, human 156 PRDM2 29334678 Cell. 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Biochem. 2018 10.1159/000486355 4 0 0 177 Humans|Male|*Testis|Neoplasm Recurrence, Local|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|Testicular Neoplasms|*Sequencing, Whole Genome|Evolution, Molecular 156 PRDM8 30458291 Gene 2018 10.1016/j.gene.2018.11.046 4 1 0 41 Male|Animals|Mice|*Histones|*Methylation|Epigenesis, Genetic|Set2 protein, human|Histone-Lysine N-Methyltransferase|SETD1B protein, human|NSD2 protein, human|KMT2A protein, human|KDM1A protein, human|Histone Demethylases|*Cyprinodontiformes|*Self-Fertilizations|PRDM2 protein, human|KDM5C protein, human|Embryonic Development|*Killifishes|*Reproduction|KMT2D protein, human 25 PRDM8 30393995 Histopathology 2018 10.1111/his.13783 0 0 0 41 *Clonal Evolution|Lymphomatoid Papulosis|*Ki-1 Antigen|Lymphoma, Primary Cutaneous Anaplastic Large Cell|Anaplastic Large Cell Lymphoma|*Skin|Skin Neoplasms|Lymph Node|Biomarkers, Tumor 25 PRDM8 29572888 Hepatology 2018 10.1002/hep.29890 6 6 0 41 Male|*Carcinoma, Hepatocellular|*Liver Neoplasms|Phosphatidylinositol 3-Kinases|Signal Transduction|Proto-Oncogene Proteins c-akt|Hep G2 Cells|Cell Proliferation|MTOR protein, human|TOR Serine-Threonine Kinases|Cell Movement|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Apoptosis 25 PRICKLE2 30080139 Elife 2018 PMC6115189 10.7554/eLife.36456 11 46 0 83 Animals|*Neural Tube|*Neurulation|Cell Polarity|Morphogenesis|Neural Plate|Xenopus Proteins|Xenopus laevis|Membrane Proteins|Epithelial Cells 50 PRICKLE2 29411465 Mol. Ecol. 2018 10.1111/mec.14509 0 0 0 83 Animals|*Temperature|Myxozoa|Parasitic Diseases, Animal|Trout|Fish Diseases|*Parasitic Infections|Disease Resistance|Kidney Diseases|SNPs|Phenotype|Host-Parasite Interactions|Genome|*Communicable Diseases|*Anemia 50 PRICKLE2 29390993 BMC Med Genomics 2018 PMC5796507 10.1186/s12920-018-0320-7 6 0 0 83 Humans|Sequencing, Next-Generation|*Intractable Epilepsy|Epilepsy|Genetic Predisposition to Disease|Mutation 50 PRIMA1 30142075 Elife 2018 PMC6156076 10.7554/eLife.37462 8 1 0 187 Mice|Animals|*Epigenetic|CpG Islands|DNA Methylation|Epigenesis, Genetic|cytidylyl-3'-5'-guanosine|*Dinucleoside Phosphates|Aging 67 PRIMA1 29374860 Pathol. Oncol. Res. 2018 10.1007/s12253-018-0382-z 6 0 0 187 *Cell Free DNA|*Liquid Biopsy|*Colorectal Cancer|Tumor DNA, Cell-Free|DNA Methylation|DNA, Neoplasm|Promoter Regions, Genetic|Biomarkers, Tumor|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|*Colonic Neoplasms|Membrane Proteins|Specimen Handling|Blood Specimen Collection 67 Prrx2 30453928 BMC Ophthalmol 2018 PMC6245782 10.1186/s12886-018-0951-7 0 4 0 246 Rats|Animals|HDAC6 protein, human|*Histone Deacetylase 6|Hydroxamic Acids|Histone Deacetylase Inhibitors|Histone Deacetylases|Acetylation|*Ischemia-Reperfusion Injury|*Retina|*Retinal Diseases|Anilides|Tubulin|*Reperfusion|Cell Line, Tumor|HDAC6 protein, rat 84 Prrx2 30351993 FASEB J. 2018 10.1096/fj.201801150R 7 3 0 246 Rats|Animals|Mice|*Peroxiredoxin I|*Brain|Subarachnoid Hemorrhage|Signal Transduction|Apoptosis|Neurons|Oxidative Stress|Brain Injuries|Neuroprotective Agents|Rats, Sprague-Dawley|Cytokines 84 Prrx2 30315937 Free Radic. Biol. Med. 2018 10.1016/j.freeradbiomed.2018.10.407 3 4 0 246 *Peroxiredoxin|*Redox|*Cytoskeletal Proteins|*Cytoskeleton|Nerve Tissue Proteins|Hydrogen Peroxide|Signal Transduction|*Transcription Factors 84 Prrx2 30132841 J. Cell. Physiol. 2018 PMC6686159 10.1002/jcp.26875 3 2 0 246 Animals|*Podocytes|*Diabetic Nephropathies|*Peroxidase|Diabetes Mellitus, Type 2|*Palmitates|*Peroxidases|Diabetes Mellitus, Experimental|Oxidative Stress|Superoxide|Palmitic Acid|Cells, Cultured|Mitochondria|Free Fatty Acids 84 Prrx2 29733327 J. Gerontol. A Biol. Sci. Med. Sci. 2018 10.1093/gerona/gly113 0 1 0 246 Mice|Animals|*Insulin Resistance|Euglycemic Clamp|*Muscle Strength|Insulin|Muscle, Skeletal|Glucose Tolerance Test|*Aging|Mice, Knockout|Glucose|Signal Transduction|Oxidative Stress|Inflammation 84 Prrx2 29605633 Int. J. Biochem. Cell Biol. 2018 10.1016/j.biocel.2018.03.019 3 9 0 246 Mice|Animals|*Insulin Resistance|*Peroxiredoxin|PTPN1 protein, human|Protein Tyrosine Phosphatase 1B|B-insulin|Insulin|*Skeletal Muscles|Signal Transduction|*Oxidation-Reduction|Glucose|Reactive Oxygen Species|Phosphorylation|Homeostasis|Biotin 84 Prrx2 29574146 Free Radic. Biol. Med. 2018 10.1016/j.freeradbiomed.2018.03.039 1 0 0 246 STAT3 protein, human|*STAT3 Transcription Factor|Peroxiredoxins|*Disulfides|Oxidation-Reduction|Hydrogen Peroxide|Kinetics|Signal Transduction 84 PRSS56 30348676 Cancer Discov 2018 10.1158/2159-8290.CD-18-0156 5 0 0 17 Humans|Mice|Animals|*Neurofibroma|Neurofibromin 1|Neurofibromatosis 1|*Skin Neoplasms|Schwann Cells|*Neoplastic Processes|Disease Models, Animal 26 PRSS56 30242838 J. Comp. Neurol. 2018 PMC6196109 10.1002/cne.24504 0 0 0 17 Rats|Animals|Mice|*Pro-Opiomelanocortin|*Ependymoglial Cells|*Rodent|*Hypothalamus|Pituitary Gland|*Gene Expression|Neural Stem Cells|In Situ Hybridization|Arcuate Nucleus|mRNA|Brain 26 PRSS56 29862063 J Ophthalmol 2018 PMC5971257 10.1155/2018/2735465 5 1 0 17 *Microphthalmos|Glaucoma, Angle-Closure|Hyperopia|Pedigree|Choroid|Retina 26 PRSS56 29529029 PLoS Genet. 2018 PMC5864079 10.1371/journal.pgen.1007244 5 3 0 17 Humans|Mice|Animals|*Refractive Error|Hyperopia|*Vision, Ocular|Myopia|Refraction, Ocular|Retina|Serine Protease|Disease Models, Animal|*Glia|PRSS56 protein, human 26 prune2 29785016 Mod. Pathol. 2018 10.1038/s41379-018-0047-1 1 0 0 110 Humans|*Carcinoma, Papillary|Intraductal Papilloma|Carcinoma, Intraductal, Noninfiltrating|Immunohistochemistry|Biomarkers, Tumor|Hyperplasia|*Adenocarcinoma, Papillary|Mutation|Breast Neoplasm 34 prune2 29571668 Brain Res. 2018 10.1016/j.brainres.2018.03.025 0 0 0 110 Humans|Mice|Animals|*Odorants|*Smell|Olfactory Bulb|Olfactory Pathways|Olfactory Perception|*Memory|Piriform Cortex|Receptors, N-Methyl-D-Aspartate 34 PSRC1 30133737 Hastings Cent Rep 2018 10.1002/hast.879 1 0 0 141 Child|Humans|*Genomics|Intellectual Disability|Exome|Developmental Disabilities|Whole Exome Sequencing|Sequence Analysis, DNA|Family|Autism|Mutation|Patient-Centered Care 90 PSRC1 29930724 Theranostics 2018 PMC6010983 10.7150/thno.22704 4 12 0 141 90 PSRC1 29714125 Per Med 2018 10.2217/pme-2017-0075 0 0 0 141 Humans|*Hyperlipoproteinemia Type II|*Heterozygote|*Multivariate Analysis|Cholesterol, LDL|Coronary Artery Disease|Cholesterol|Risk Factors 90 PSRC1 29434151 Intern. Med. 2018 PMC6064700 10.2169/internalmedicine.9613-17 0 2 0 141 Male|Humans|Middle Aged|*Facial Nerve|*Lymphoproliferative Disorders|*Facial Paralysis|Kidney Transplantation|*Central Nervous System|Immunosuppressive Agents|Epstein-Barr Virus Infections|Immunosuppression|Rituximab|Postoperative Complications 90 PSRC1 29378206 J. Mol. Cell. Cardiol. 2018 10.1016/j.yjmcc.2018.01.013 3 16 0 141 Mice|Humans|Animals|*Apo E|*Serine|Genome-Wide Association Study|*Atherosclerosis|Plaque, Atherosclerotic|Macrophages|*Disease Progression|NF-kappa B|RAW 264.7 Cells|Inflammation|Aorta|Signal Transduction|Mice, Inbred C57BL|PSRC1 protein, human|Phosphoproteins 90 PTAFR 30476590 J. Steroid Biochem. Mol. Biol. 2018 10.1016/j.jsbmb.2018.11.013 4 1 0 671 Humans|*Rhinovirus|ICAM1 protein, human|*Intercellular Adhesion Molecule-1|*Cells, Epithelial|platelet activating factor receptor|*Platelet Membrane Glycoproteins|Respiratory Mucosa|*Receptors, G-Protein-Coupled|25-hydroxyvitamin D|*Vitamin D|Bronchi|*Vitamins|Cells, Cultured|Cell Line|NF-kappa B|Upper Respiratory Infections 39 PTAFR 30147646 Front Neuroanat 2018 PMC6095973 10.3389/fnana.2018.00061 1 2 0 671 Humans|Homeodomain Proteins|*Phenotypes|Nerve Tissue Proteins|Cerebellum|Hippocampus 39 PTAFR 30008927 Oncol Lett 2018 PMC6036417 10.3892/ol.2018.8935 1 1 0 671 39 PTAFR 29890994 Acta Neuropathol Commun 2018 PMC5996550 10.1186/s40478-018-0544-y 8 14 0 671 39 PTAFR 29464008 Theranostics 2018 PMC5817119 10.7150/thno.20846 22 17 0 671 39 PTAFR 29463987 Theranostics 2018 PMC5817098 10.7150/thno.23364 4 7 0 671 39 PTAFR 29459885 Front Oncol 2018 PMC5807395 10.3389/fonc.2018.00010 4 26 0 671 Humans|*Ligands|platelet activating factor receptor|Platelet Membrane Glycoproteins|Receptors, G-Protein-Coupled|Platelet Activating Factor|*Antineoplastic Agents|*Protein Transport|Signal Transduction|Cell Line, Tumor|*Protective Agents|Keratinocytes|*Cell Death 39 PTBP2 30568224 Oncogene 2018 PMC6474811 10.1038/s41388-018-0639-8 6 15 0 322 *RNA Precursors|*Telomerase|Telomere Shortening|Telomere|Polypyrimidine Tract-Binding Protein|NOVA1 protein, human|*RNA-Binding Proteins|Alternative Splicing|Heterogeneous-Nuclear Ribonucleoproteins|RNA Splicing|Exons|Lung Cancer|Gene Expression Regulation, Neoplastic|Nerve Tissue Proteins|Neurons 77 PTBP2 30310857 Biophys Rep 2018 PMC6153489 10.1007/s41048-018-0066-y 4 1 0 322 Animals|Polypyrimidine Tract-Binding Protein|*Neurons|Alternative Splicing|RNA-Binding Proteins|Exons|Nerve Tissue Proteins|*Mammals|Gene Expression Regulation, Developmental|RNA Splicing|Cells, Cultured|Brain 77 PTBP2 29851470 Biochemistry 2018 PMC6211845 10.1021/acs.biochem.8b00256 2 33 0 322 *Polypyrimidine Tract-Binding Protein|Heterogeneous-Nuclear Ribonucleoproteins|RNA Splicing|Exons|RNA Precursors|Alternative Splicing|RNA-Binding Proteins|*Post-Translational Modifications|Nerve Tissue Proteins|RNA, Messenger|Cell Differentiation|Brain 77 PTBP2 29581412 RNA 2018 PMC5959245 10.1261/rna.065508.117 5 0 0 322 *Heterogeneous-Nuclear Ribonucleoprotein L|*Exons|RNA Splicing|RNA Precursors|Alternative Splicing|Base Sequence|RNA, Messenger|Regulatory Sequences, Nucleic Acid 77 PTBP2 29441128 Mol Cytogenet 2018 PMC5800070 10.1186/s13039-018-0363-7 4 0 0 322 Humans|*Obesity|Prader-Willi Syndrome|DNA Copy Number Variations|*Microarray Analysis|Phenotype|Comparative Genomic Hybridization|Chromosome Deletion|*Chromosomes B 77 PTBP2 29415469 Int J Mol Sci 2018 PMC5855702 10.3390/ijms19020480 31 7 0 322 Humans|*PTB Splicing Factor|*Glioblastoma|SRSF3 protein, human|*Serine-Arginine Splicing Factors|Heterogeneous-Nuclear Ribonucleoproteins|Brain Neoplasms|Alternative Splicing|Gene Expression Regulation, Neoplastic|Exons|Cell Line, Tumor|RNA, Messenger|Cell Proliferation|Binding Sites|Gene Knockdown Techniques|SRSF1 protein, human 77 PTPRCAP 30482149 Biochemistry Mosc. 2018 10.1134/S0006297918110081 0 2 0 34 Humans|*Casein Kinase II|HEK293 Cells|PTPRC protein, human|Leukocyte Common Antigens|*Phosphatase, Phosphoprotein|Intracellular Signaling Peptides and Proteins|Phosphoproteins|*B-Lymphocytes|Phosphorylation|CSNK2A1 protein, human|Membrane Proteins|Lymphocyte Activation|Lymphocytes|Amino Acid Sequence 48 PTPRE 30249496 Bioorg. Med. Chem. 2018 10.1016/j.bmc.2018.09.022 0 1 0 152 PTPRE protein, human|*Receptor-Like Protein Tyrosine Phosphatases, Class 4|*Osteoclasts|Phosphorylation|src-Family Kinases|Cell Differentiation|Amino Acid Sequence|Proteins|Cell Line|Protein Tyrosine Phosphatases, Non-Receptor|Acetamides 70 PTPRE 29904591 F1000Res 2018 PMC5981198 10.12688/f1000research.14048.2 2 2 0 152 70 PTPRE 29930709 Mol Cytogenet 2018 PMC5991433 10.1186/s13039-018-0384-2 1 0 0 152 Humans|Male|*Paternal Inheritance|*Chromosome Aberrations|*Sequencing, Whole Genome|Translocation, Genetic|Chromosome Mapping|In Situ Hybridization, Fluorescence|*Fathers|Phenotype 70 PTPRE 29410024 Mol. Cell. Endocrinol. 2018 10.1016/j.mce.2018.01.020 7 3 0 152 Humans|*Pituitary Neoplasms|*DNA Methylation|Epigenesis, Genetic|Adenoma|Promoter Regions, Genetic|STAT5A protein, human|Tumor Suppressor Proteins|Pituitary Gland|Gene Expression Regulation, Neoplastic|Downregulation|Upregulation|Brain Neoplasms|STAT5 Transcription Factor|CNKSR1 protein, human|Intracellular Signaling Peptides and Proteins 70 PTPRE 29365082 DNA Res. 2018 PMC6014285 10.1093/dnares/dsy001 4 10 0 152 Pregnancy|Humans|Female|Swine|Animals|Infant, Newborn|*DNA Methylation|Epigenesis, Genetic|Preterm Infants|Enterocolitis, Necrotizing|Intestines|Animals, Newborn|Intestinal Mucosa|Microbiota|Anti-Bacterial Agents|Premature Birth|*Communicable Diseases|Bacteria|Innate Immune Response|MIRN126 microRNA, human|MicroRNAs 70 PTPRM 30274773 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.09.150 0 2 0 98 Humans|*Tyrosine|*Cell Migration|*Glioma|*Protein Tyrosine Phosphatase|N-Acetylglucosaminyltransferases|protein phosphatase 6|*Phosphoprotein Phosphatases|Signal Transduction|Phosphorylation|Glycosylation|RNA Interference|Cell Line, Tumor|Acetylglucosamine|Glycans|Transfections|RNA, Messenger 52 PTPRM 29507701 Oncotarget 2018 PMC5823647 10.18632/oncotarget.24253 1 21 0 98 Humans|4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|*Pyrimidines|Fusion Proteins, bcr-abl|Protein Kinase Inhibitors|PTPRG protein, human|*Receptor-Like Protein Tyrosine Phosphatases, Class 5|Drug Resistance, Neoplasm|PTPRC protein, human|*Leukocyte Common Antigens|PTPRA protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 4 52 PURG 30254369 Nat Commun 2018 PMC6156567 10.1038/s41467-018-06305-y 3 0 0 44 *Catalytic Domain|Directed Molecular Evolution|Thermodynamics|Protein Engineering|Biocatalysis|Static Electricity|Models, Molecular|Catalysis|Bioinformatics 36 PURG 30149862 Meth. Enzymol. 2018 10.1016/bs.mie.2018.06.007 0 0 0 44 *Hydrolysis|diisopropyl-fluorophosphatase|Phosphoric Triester Hydrolases|*Organophosphates|Substrate Specificity|Models, Molecular|Binding Sites 36 PURG 30006361 J. Neurosci. 2018 PMC6083454 10.1523/JNEUROSCI.0192-18.2018 4 1 0 44 Humans|Female|*Propranolol|Double-Blind Method|Bayes Theorem|*Adrenergic beta-Antagonists|Dopamine Antagonists|Noradrenaline|Dopamine|Amisulpride|Decision Making|Obsessive Compulsive Disorder 36 PYY3 30399314 J. Med. Chem. 2018 10.1021/acs.jmedchem.8b01046 4 0 0 0 Peptide YY|Receptors, Neuropeptide Y|Amino Acid Sequence|Protein Binding|Structure-Activity Relationship|Intake Regulation, Food|Peptide Fragments|Obesity 181 PYY3 30230821 Biomacromolecules 2018 10.1021/acs.biomac.8b01209 2 0 0 0 Humans|*Peptide, PYY|*Peptide Hormones|*Protein Binding|Protein Structure, Secondary|Amino Acid Sequence|Peptide Fragments|Structure-Activity Relationship|*Signal Transduction|*Stomach|Polyethylene Glycols 181 PYY3 30148973 Appl Physiol Nutr Metab 2018 10.1139/apnm-2018-0197 0 0 0 0 Humans|Male|*Appetite|peptide YY (3-36)|Peptide YY|*Overweight|*Body Weight|Ghrelin|Appetite Regulation|Glucagon-Like Peptide 1|Weight Loss|Energy Intake|Fasting|Exercise|Peptide Fragments 181 PYY3 30096700 Eat Behav 2018 10.1016/j.eatbeh.2018.08.001 2 1 0 0 Adult|Humans|*Persea|*Cross-Over Studies|*Gastrointestinal Microbiome|*Overweight|*Meals|*Postprandial Period|*Gastrointestinal Hormones|Peptide YY|Appetite|Satiety Response|Glucagon-Like Peptide 1|Hunger|Energy Intake|Obesity|Ghrelin|Insulin|Lunch 181 PYY3 29993319 Metab Syndr Relat Disord 2018 PMC6167613 10.1089/met.2018.0075 2 0 0 0 *Obesity|Anti-Obesity Agents|Weight Loss|Bariatric Surgery|Glucagon-Like Peptide 1|*Combined Modality Therapy|Incretin|Diet 181 RAD54B 30559372 Sci Rep 2018 PMC6297154 10.1038/s41598-018-36275-6 1 0 0 120 Humans|*Oocytes|Zygotes|Fertilization|Fertilization in Vitro|Sperm Injections, Intracytoplasmic|Cell Cycle Genes|*Transcriptome Profiling|Cell Nucleus|Transcriptome Profiles|Genes, Regulator|CDC7 protein, human|Protein-Serine-Threonine Kinases|Cell Cycle Proteins|PHF5A protein, human|Carrier Proteins 67 RAD54B 30394818 J. 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U.S.A. 2018 PMC6156624 10.1073/pnas.1804740115 4 2 0 152 RHOA protein, human|*rhoA GTP-Binding Protein|*Guanine Nucleotide Exchange Factor|Small GTPases|Protein Prenylation|Protein Binding|Guanosine Triphosphate|Amino Acid Sequence|Binding Site|*Molecular Chaperone 48 RAP1GDS1 29940100 Biochemistry 2018 PMC6686180 10.1021/acs.biochem.8b00567 2 1 0 152 RHOA protein, human|*rhoA GTP-Binding Protein|Guanosine Diphosphate|Prenylation, Protein|Guanosine Triphosphate|Small GTPases|Guanine Nucleotide Exchange Factors|Protein Binding|geranylgeranyltransferase type-I|Alkyl and Aryl Transferases|Kinetics 48 RAP1GDS1 29606096 BMC Cancer 2018 PMC5879922 10.1186/s12885-018-4227-7 11 4 0 152 Humans|Male|*Alternative Splicing|Clk dual-specificity kinases|*Protein-Tyrosine Kinases|*Protein-Serine-Threonine Kinases|*PC3 Cells|Phosphorylation|*Hypoxia|Exons|RNA-Binding Proteins|*Prostate Cancer|RNA Splicing|RNA, Messenger|Thiazoles 48 rap2a 30135582 Nature 2018 PMC6128698 10.1038/s41586-018-0444-0 34 17 0 251 Animals|Adaptor Proteins, Signal Transducing|Phosphoproteins|Intracellular Signaling Peptides and Proteins|Transcription Factors|Protein-Serine-Threonine Kinases|Signal Transduction|Extracellular Matrix|Mechanotransduction, Cellular|Cytoskeleton 128 rap2a 30049443 Biochem. 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Biochem. 2018 10.1007/s11010-018-3294-z 7 0 0 251 *Cyclic AMP|*Guanine Nucleotide Exchange Factors|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Cyclic AMP-Dependent Protein Kinases|rap1 GTP-Binding Proteins|Second Messenger Systems|Signal Transduction|Cell Migration|Cancer 128 rap2a 29352039 Blood 2018 PMC5854849 10.1182/blood-2017-08-802918 0 1 0 251 Animals|*Erythrocyte|Plasmodium falciparum|Merozoites|Malaria, Falciparum|Antigens, Protozoan|Protozoan Proteins|Malaria|Host-Parasite Interactions|Basigin|Protein Binding|Carrier Proteins 128 rap2a 29309643 Nucleic Acids Res. 2018 PMC5829742 10.1093/nar/gkx1306 11 18 0 251 Humans|Male|AR protein, human|*Receptors, Androgen|abiraterone|Androgen Antagonists|*Chromatin|*Androstenes|Phenylthiohydantoin|Prostatic Neoplasms, Castration-Resistant|Drug Resistance, Neoplasm|*RNA Splicing|Cell Line, Tumor|Protein Isoforms|Gene Expression Regulation, Neoplastic|Castration|Transcriptome|Signal Transduction 128 RAPGEF6 30520388 Microrna 2018 10.2174/2211536608666181206124922 4 1 0 96 *Cell Proliferation|Receptor, ErbB-2|Gene Expression Regulation, Neoplastic|MicroRNAs|Biomarkers, Tumor|*Cell Cycle|Cell Line, Tumor|Signal Transduction 25 RAPGEF6 30135582 Nature 2018 PMC6128698 10.1038/s41586-018-0444-0 34 17 0 96 Animals|Adaptor Proteins, Signal Transducing|Phosphoproteins|Intracellular Signaling Peptides and Proteins|Transcription Factors|Protein-Serine-Threonine Kinases|Signal Transduction|Extracellular Matrix|Mechanotransduction, Cellular|Cytoskeleton 25 RAPGEF6 29747665 Mol Brain 2018 PMC5946393 10.1186/s13041-018-0370-y 2 0 0 96 Animals|Mice|*Guanine Nucleotide Exchange Factors|*Behavior Rating Scale|*Small GTPases|Maze Test|Fear|Conditioning, Psychological|Anxiety|Behavior, Animal|Mice, Knockout|Spatial Memory|Social Behavior|Working Memory|Schizophrenia|Motor Activity|Swimming|Cognitive Function|Rapgef6 protein, mouse 25 RAPGEF6 29520708 J. Appl. Genet. 2018 10.1007/s13353-018-0436-7 3 0 0 96 Male|Animals|Cattle|*DNA Copy Number Variations|*Acids, Fatty|Phenotype|Genotype|Breeding|Red Meat|Genetic Association Studies|Allele Frequency|Polymorphism, Single Nucleotide|Muscle, Skeletal 25 RASGEF1B 30134803 Mol. Med. 2018 PMC6016867 10.1186/s10020-018-0018-5 0 0 0 25 Genome-Wide Association Study|Genetic Loci|Polymorphism, Single Nucleotide|Genotype|*Parathyroid Hormone 28 RASGEF1B 29464180 Int J Genomics 2018 PMC5804362 10.1155/2017/2790864 3 4 0 25 Nonalcoholic Fatty Liver Disease|Liver|Diet, High-Fat|PPAR alpha|Plant Extracts|Oxidative Stress 28 RAX2 30377383 Genet. Med. 2018 PMC6752271 10.1038/s41436-018-0345-5 2 0 0 14 *Retina|Retinitis Pigmentosa|Genes, Recessive|Eye Proteins|Electroretinography|Pedigree|DNA Mutational Analysis|Homozygote|Genetic Association Studies|Phenotype|Mutation, Missense 25 RAX2 29797594 J. Cell. Biochem. 2018 10.1002/jcb.27059 2 1 0 14 Humans|Child|*Pediatric Obesity|CpG Islands|DNA Methylation|cytidylyl-3'-5'-guanosine|*Dinucleoside Phosphates|Epigenesis, Genetic|Genome-Wide Association Study|DNA|HDAC4 protein, human|Repressor Proteins|Histone Deacetylases|Cohort Studies 25 RBM24 30267374 Protein Cell 2018 PMC6538757 10.1007/s13238-018-0578-8 7 0 0 140 Humans|Animals|Mice|*Alternative Splicing|*Cardiomyopathy, Dilated|*Mice, Knockout|*RNA Binding Protein|TTN protein, human|Titin|Sarcomeres|RNA Splicing|Myocardium|Myocytes, Cardiac|Heart Failure|Heart Diseases|Organogenesis|RBM24 protein, human 41 RBM24 30133047 Dev. Dyn. 2018 10.1002/dvdy.24666 2 0 0 140 Pregnancy|Female|Mice|Animals|*Embryonic Development|*Ear, Inner|RNA-Binding Proteins|*Lens, Crystalline|*Nasal Epithelium|Alternative Splicing|mRNA|Cell Differentiation|RNA Splicing 41 RBM24 30076363 Sci Rep 2018 PMC6076270 10.1038/s41598-018-29552-x 3 31 0 140 Mice|Animals|*Viruses, Adeno-Associated|RNA Binding Protein|Heart|Alternative Splicing|TTN protein, human|Titin|RNA Splicing|Myocardium|Mice, Knockout|*Fibrosis 41 RBM24 29760415 Emerg Microbes Infect 2018 PMC5951808 10.1038/s41426-018-0091-4 4 22 0 140 *Hepatitis B virus|Hepatitis B Virus Infection|pgRNA|RNA, Viral|Viral Core Proteins|Virus Replication|RNA-Binding Domains|Gene Expression Regulation, Viral|Hepatoma|Liver Neoplasms|DNA Replication 41 RBM24 29380205 Protein Cell 2018 PMC6208484 10.1007/s13238-018-0507-x 4 2 0 140 Humans|*Hepacivirus|*RNA Binding Protein|*Hepatitis C|Virus Replication|RNA, Viral|5' UTR|Ribosomes|Protein Biosynthesis|3' UTRs|Protein Binding|RBM24 protein, human 41 RBM24 29358667 Cell Death Differ. 2018 PMC5988652 10.1038/s41418-017-0029-8 10 3 0 140 Mice|Animals|*Tumor Suppressor Protein p53|RNA Binding Protein|mRNA|3' Untranslated Regions|mRNA Translation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|EIF4E|Protein Binding|Heart|Mice, Knockout|*Organogenesis 41 RBMS3 30279231 Clin. Cancer Res. 2018 10.1158/1078-0432.CCR-18-2554 7 3 0 104 Humans|Female|*Carcinoma, Ovarian Epithelial|Neoplasm Recurrence, Local|*Ovarian Neoplasms|Drug Resistance, Neoplasm|Cisplatin|Gene Expression Regulation, Neoplastic|beta Catenin|*Catenins|Wnt Signaling Pathway|Cell Line, Tumor|MicroRNAs|Cell Proliferation|Xenograft Model Antitumor Assays|RBMS3 protein, human|Trans-Activators|RNA-Binding Proteins|MIRN126 microRNA, human 41 RBMS3 29965897 J. Glaucoma 2018 10.1097/IJG.0000000000000928 1 0 0 104 *Exfoliation Syndrome|Genome-Wide Association Study|Glaucoma, Open Angle|Glaucomas|Trabecular Meshwork|Extracellular Matrix|Iris|Elastic Tissue 41 RBMS3 29328463 Oncol. Rep. 2018 PMC5802034 10.3892/or.2018.6207 10 0 0 104 Humans|*RNA, Long Noncoding|*Thyroid Cancer, Papillary|RNA, Micro|Prognosis|mRNA|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Carcinoma, Thyroid|Biomarkers, Tumor|Gene Ontology|Computational Biology|Kaplan-Meier Estimate|Cohort Studies 41 RC3H1 30295819 Nucleic Acids Res. 2018 PMC6294493 10.1093/nar/gky908 1 0 0 430 Humans|Mice|Animals|Binding Site|RNA Stability|RNA Binding Protein|mRNA|Protein Binding|Nucleic Acid Conformation|Gene Expression Regulation|Ubiquitin-Protein Ligases|Crystallography, X-Ray|Conserved Sequence|Models, Molecular 71 RC3H1 30232334 Nat Commun 2018 PMC6145892 10.1038/s41467-018-06184-3 4 0 0 430 *3' UTR|*mRNA|mRNA Decay|Binding Sites|RNA-Binding Proteins|Nucleic Acid Conformation|Protein Binding|Base Sequence|Gene Expression Regulation|Gene Expression|Ubiquitin-Protein Ligases|Crystallography, X-Ray|Models, Molecular 71 RC3H1 29751106 J Proteomics 2018 10.1016/j.jprot.2018.05.007 3 5 0 430 *Curcumin|Fibroblasts|Cell Line, Tumor|Co-cultures|Gene Expression Profiling|Signal Transduction|Transforming Growth Factor beta|Cancer-Associated Fibroblasts|Downregulation 71 RC3H1 29657255 J Clin Exp Hematop 2018 PMC6413152 10.3960/jslrt.17036 0 0 0 430 Animals|Mice|IL10 protein, human|*Interleukin-10|*RNA, Small Interfering|*Ribosomal Proteins|Reproducibility of Results|Macrophages|Tumor Necrosis Factor-alpha|Cytokines|Lipopolysaccharides|Interferon-gamma|mRNA|Gene Expression Regulation|Bone Marrow Cells|Cells, Cultured 71 RC3H1 29352114 Nat Commun 2018 PMC5775257 10.1038/s41467-017-02582-1 9 25 0 430 Humans|Mice|Animals|*mRNA|mRNA Decay|RNA-Binding Proteins|3' UTRs|Inducible T-Cell Co-Stimulator Protein|Receptors, OX40|Binding Sites|Ubiquitin-Protein Ligases|Protein Binding|Protein Structure, Secondary|Gene Expression|NUFIP2 protein, human|Nuclear Proteins|ICOS protein, human|roquin-2 protein, human|Repressor Proteins|Icos protein, mouse 71 REG1A 30240355 Clin. Chem. Lab. Med. 2018 10.1515/cclm-2018-0154 0 0 0 2130 Humans|*Procalcitonin|REG1A protein, human|*Lithostathine|Calcitonin|Protein Precursors|Biomarkers|Febrile Neutropenia|*Neoplasms|C-Reactive Protein|Receiver Operating Characteristic|Sepsis|Prospective Studies|Calcitonin Gene-Related Peptide|Carrier Proteins|Membrane Glycoproteins|Emergency Department 307 REG1A 30099958 Exp. Biol. Med. (Maywood) 2018 PMC6180405 10.1177/1535370218794418 1 1 0 2130 Infant|Humans|Child, Preschool|Aged|*mRNA|*Intestine, Small|Lactulose|*Feces|*Rural Population|Permeability|Growth Disorders|Intestinal Mucosa|Mannitol|Diagnostic Tests, Routine|REG1A protein, human|Lithostathine 307 REG1A 30092268 Neurobiol. Dis. 2018 10.1016/j.nbd.2018.07.029 1 4 0 2130 Humans|Animals|Rats|*Phosphorylation|Glycogen Synthase Kinase 3|*Tauopathies|Neurofibrillary Tangles|tau Proteins|Alzheimer Disease|Neurons|Nerve Degeneration|Progressive Supranuclear Palsy|Brain|Axons|Hippocampus|Disease Models, Animal 307 REG1A 29794791 Medicine (Baltimore) 2018 PMC6392713 10.1097/MD.0000000000010871 0 6 0 2130 Adult|Humans|*Mycosis Fungoides|Cutaneous T Cell Lymphoma|Sezary Syndrome|Skin Neoplasms|Biomarkers, Tumor|Leukemia-Lymphoma, Adult T-Cell|Biopsies|Gene Expression Profiling|REG1A protein, human|Lithostathine 307 REG1A 29330507 Sci Rep 2018 PMC5766629 10.1038/s41598-017-18325-7 24 12 0 2130 kushen|*Carcinoma, Hepatocellular|*Liver Neoplasms|Chromatography, Liquid|Tandem Mass Spectrometry|oxymatrine|Quinolizines|Alkaloids|Drugs, Chinese Herbal|N-methylcytisine|matrine|*Antineoplastic Agents|Traditional Chinese Medicine|Antineoplastic Agents, Phytogenic|CASP3 protein, human|CASP3|Matrix Metalloproteinase 2|Cell Proliferation 307 REG1A 29310262 Talanta 2018 10.1016/j.talanta.2017.11.031 1 0 0 2130 *Liposomes|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|*Immunoassay|*Biotinylations|*Proteins|Biomarkers, Tumor|Specificity|Nucleic Acid Amplification Techniques|*Immunologic Tests|ELISA 307 REG1B 30137272 J Crohns Colitis 2018 PMC6236200 10.1093/ecco-jcc/jjy117 6 0 0 24 Humans|*Colitis, Ulcerative|*DNA Methylation|*B-DNA|Crohn Disease|Colon|Intestinal Mucosa|Gene Expression|Gene Expression Profiling|Biopsies 36 RELT 30506946 Clin. Genet. 2018 PMC6392136 10.1111/cge.13487 6 9 0 87 Mice|Animals|*Amelogenesis Imperfecta|RELT|*Mutations|*Receptors, Tumor Necrosis Factor|Homozygote|Ameloblasts|Phenotype|Pedigree|Odontoblasts 46 RELT 30401374 Transplant. Proc. 2018 10.1016/j.transproceed.2018.03.040 3 1 0 87 Humans|Liver Transplantation|*Reoperation|*Prognosis|Living Donors|Liver Failure|*Liver|Hepatitis C|Graft Survival|Retrospective Studies|Risk Factors|Time Factors|East Asia 46 RELT 30247315 Transplantation 2018 10.1097/TP.0000000000002460 0 0 0 87 *Antiviral Agents|*Liver Transplantation|*Reoperation|*Hepatitis C, Chronic|Hepatitis C|Hepacivirus|Ribavirin|End Stage Liver Disease|Liver Cirrhosis|Virus Activation|Drug Therapy, Combination|Recurrence|Liver|Risk Factors|Genotype|Immunosuppressive Agents 46 RELT 30138536 Eur. J. Immunol. 2018 10.1002/eji.201847633 2 4 0 87 Mice|Animals|RELT|Receptors, Tumor Necrosis Factor|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Lymphocyte Activation|Adoptive Transfer|Tissues, Lymphoid|Mice, Inbred C57BL 46 RELT 30080732 Ann. Surg. 2018 10.1097/SLA.0000000000002897 0 0 0 87 Adult|Humans|*Living Donors|*Liver Transplantation|*Retrospective Studies|Hepatectomy|Liver|Graft Survival|Organ Size|Treatment Outcome|Postoperative Complications 46 RELT 29752313 J. Immunol. 2018 PMC6008220 10.4049/jimmunol.1800101 6 5 0 87 Animals|*DNA Methylation|*Tuberculosis|*Schistosomiasis|Ascariasis|Ascaris lumbricoides|Th1 Cells|Interferon-gamma|Cytokines|Antigens, Helminth 46 Resp18 29964075 Neurochem. Int. 2018 10.1016/j.neuint.2018.06.010 0 0 0 423 Mice|Animals|*Dopaminergic Neurons|*Parkinson Disease|*1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|Substantia Nigra|Mice, Knockout|*Disease Models, Animal|Parkinsonian Disorders|MPTP Poisoning|Corpus Striatum|Mice, Inbred C57BL|Tyrosine Hydroxylase|TYRP1 protein, human|*Membrane Glycoproteins|Synuclein|Dopamine|Cells, Glial 23 Resp18 29570433 Physiol. Genomics 2018 PMC6008117 10.1152/physiolgenomics.00008.2018 1 0 0 423 Rats|Animals|*Dahl Salt-Sensitive Rats|*Sodium Chloride, Dietary|regulated endocrine secretory protein 18|*Hypertension|*Nerve Tissue Proteins|*Kidney|Blood Pressure|*Sodium Chloride|Kidney Diseases|Quantitative Trait Loci|Chromosome Mapping|Systole|Phenotype|Genetic Predisposition to Disease|Gene Expression 23 RETNLB 30297626 Int J Mol Sci 2018 PMC6213237 10.3390/ijms19103064 3 16 0 201 Humans|*Non-alcoholic Fatty Liver Disease|*Gastrointestinal Microbiome|Liver|proctolin|*Neuropeptides|FGF19 protein, human|Fibroblast Growth Factors|*Oligopeptides|Obesity|Glucagon-Like Peptide 1 152 RETNLB 30120989 Int. J. Biochem. Cell Biol. 2018 10.1016/j.biocel.2018.08.005 0 8 0 201 Humans|TGFB1 protein, human|*Transforming Growth Factor beta1|SMAD2 protein, human|*Smad2 Protein|*Endothelium|Human Umbilical Vein Endothelial Cells|Epithelial-Mesenchymal Transition|Cell Movement|Signal Transduction|Cells, Cultured|Pulmonary Fibrosis|Mesenchymal Stem Cells|Cell Proliferation 152 RETNLB 30103798 J Transl Med 2018 PMC6090719 10.1186/s12967-018-1597-1 1 5 0 201 Mice|Animals|*Lactobacillus salivarius|*Antibiotics|*Lung|Toll-Like Receptor 4|NF-kappa B|Macrophages, Alveolar|Tumor Necrosis Factor-alpha|Signal Transduction|Immunity, Innate|*Ventilator|Mice, Inbred C57BL 152 RETNLB 29761507 J Surg Oncol 2018 10.1002/jso.25078 6 0 0 201 *Up-Regulation|*Adipokine|*Colorectal Cancer|Receptors, Adiponectin|Prognosis|Biomarkers, Tumor|Osteopontin|*Colonic Neoplasms|Adiponectin|*Transcriptional Activation|RNA, Messenger 152 RETNLB 29728628 Sci Rep 2018 PMC5935686 10.1038/s41598-018-25321-y 0 1 0 201 Mice|Animals|*Resistin|*Asthma|Airway Remodeling|Lungs|Allergens|Hypersensitivity|Goblet Cells|Inflammation|Mice, Inbred C57BL|Cytokines|Disease Models, Animal|Retnlb protein, mouse|Hormones, Ectopic 152 RHBDF1 30279141 EBioMedicine 2018 PMC6197618 10.1016/j.ebiom.2018.09.038 2 13 0 79 Humans|*Clathrin-Coated Vesicles|*Protein Transport|Auxilins|Signal Transduction|*Neoplastic Processes|*Transforming Growth Factor|*Disease Progression|Endocytosis|ErbB Receptors|HSC70 Heat-Shock Proteins|*Cell Movement|Receptors, G-Protein-Coupled 30 RHBDF1 29727209 FASEB J. 2018 10.1096/fj.201800016R 1 1 0 79 Humans|Mice|Animals|Cell Polarity|Cells, Epithelial|Cell Line, Tumor|Cell Proliferation|kalinin|Cell Adhesion Molecules|Cell Transformation, Neoplastic|Short Hairpin RNA 30 RHBDF1 29708298 Macromol Rapid Commun 2018 10.1002/marc.201800068 3 4 0 79 *Gene Editing|*CRISPR|*CRISPR-Cas Systems|*Polymer|CRISPR-Associated Protein 9|Guide RNA|*Plasmid|*Cations|Gene Transfer Techniques|Transfection|Nanoparticles 30 RHBDF1 29654741 Exp. Cell Res. 2018 10.1016/j.yexcr.2018.04.009 5 22 0 79 Humans|Animals|Mice|Mice, Nude|*Mice, Inbred BALB C|*Wnt Signaling Pathway|*Epithelial-Mesenchymal Transition|*Colorectal Cancer|*Adenomatous Polyposis Coli|beta Catenin|Cell Proliferation|*Catenins|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Transformation, Neoplastic|*Colonic Neoplasms 30 RIMS2 30084954 Hum. Mol. Genet. 2018 PMC6454433 10.1093/hmg/ddy272 3 0 0 81 Mice|Animals|*Genes, Homeobox|*Retina|*Photoreceptor Cells, Vertebrate|Photoreceptors, Cone|Retinal Rod Photoreceptor Cells|Homeodomain Proteins|Trans-Activators|Transcription Factor|Eye Proteins|Gene Expression Regulation|Cell Differentiation|*Mammals|*Neurogenesis|pikachurin protein, mouse|Carrier Proteins|Nerve Tissue Proteins|REEP6 protein, mouse|Membrane Transport Proteins 35 RIMS2 29696701 J. Anim. Breed. Genet. 2018 10.1111/jbg.12326 2 0 0 81 Cattle|Animals|*Studies, Genome-Wide Association|*Body Weight|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Genotype|Breeding|Phenotype|Model, Linear|Allele Frequency|*Bones|MAP2K6 protein, human|MAP Kinase Kinase 6 35 RNASEH1 30591567 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6338839 10.1073/pnas.1810409116 12 2 0 176 Humans|*G-Quadruplexes|*Ligands|*B-DNA|*R-Loop Structures|*Genome Instability|DNA|*Cancer|Chromosome Structures|Genome Mapping|DNA Damage 47 RNASEH1 30541148 Nucleic Acids Res. 2018 PMC6393312 10.1093/nar/gky1233 1 88 0 176 *RNA Polymerase II|Cell Cycle Proteins|DNA-Binding Proteins|Ataxia Telangiectasia Mutated Proteins|Nuclear Proteins|DNA Damage|Phosphorylation|Tumor Suppressor Proteins|Signal Transduction|Ataxia-Telangiectasia|Checkpoint Kinase 1|Protein Kinases|*Transcription Factors|Chromatin|G2 Phase Cell Cycle Checkpoints|Ionizing Radiation 47 RNASEH1 30345028 F1000Res 2018 PMC6171737 10.12688/f1000research.15579.1 3 0 0 176 47 RNASEH1 30190335 EMBO Mol Med 2018 PMC6180300 10.15252/emmm.201708698 3 13 0 176 *Mutations|Mitochondrial Diseases|Mitochondria|Oxidative Phosphorylation|Mitochondrial Proteins|DNA, Mitochondrial|Sequencing, Whole Exome|Fibroblasts 47 RNASEH1 30054334 Cancer Res. 2018 PMC6139047 10.1158/0008-5472.CAN-17-3970 13 2 0 176 *Spliceosomes|*R-Loop Structures|*Myelodysplastic Syndromes|Splicing Factor U2AF|RNA Splicing Factors|RNA Splicing|*Mutations|Serine-Arginine Splicing Factors|Ribonucleoproteins|Nuclear Proteins|Phosphoproteins|*Protein Kinase Inhibitors 47 RNASEH1 29497062 Sci Rep 2018 PMC5832799 10.1038/s41598-018-21806-y 2 14 0 176 *DNA Breaks, Double-Stranded|*RNA|*DNA Helicases|SETX protein, human|*RNA Helicase|DNA Repair|Endonucleases|Genome Instability|DNA-Binding Proteins|DNA|Transcription Factors 47 RNF39 29492303 Environ Epigenet 2018 PMC5804541 10.1093/eep/dvx001 3 4 0 8 Humans|Male|*Pollutants|*DNA Methylation|CpG Islands|*Leukocytes|Polychlorinated Biphenyls|Environmental Pollution|Carcinogenesis 22 RP1L1 30025130 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24033 1 0 0 12 Humans|Retinitis pigmentosa 1|*Retinitis Pigmentosa|*Mutations|Macular Degeneration|Electroretinography|Phenotype|Fluorescein Angiography|Eye Proteins|Retina|*Cohort Studies|Pedigree|Tomography, Optical Coherence|Visual Acuity|Genotype|RP1L1 protein, human 47 RP1L1 29555955 Sci Rep 2018 PMC5859282 10.1038/s41598-018-22096-0 15 0 0 12 Humans|*Cone-Rod Dystrophies|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|Retinitis Pigmentosa|Electroretinography|DNA Mutational Analysis|Mutations|Sequencing, Next-Generation|Phenotype|Genotype-Phenotype Correlations|Retina|Eye Proteins|Pedigree|Macular Degeneration|Coherence Tomography, Optical|Visual Acuity|NPHP1 protein, human|Membrane Proteins 47 rrad 30463512 Genet. Sel. Evol. 2018 PMC6249784 10.1186/s12711-018-0433-7 5 0 0 621 Animals|*Eimeria tenella|*Chickens|*Coccidiosis|Poultry Diseases|Cecum|Phenotype|Gain, Weight|Genetic Variation 121 rrad 30419821 BMC Genomics 2018 PMC6233266 10.1186/s12864-018-5211-y 4 3 0 621 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|RELA protein, human|Transcription Factor RelA|NF-kappa B|Osteosarcoma|*Genes, cdc|*Ionizing Radiation|Transcriptional Activation|Gene Expression Regulation, Neoplastic|Binding Sites|Promoter Regions, Genetic|Cell Line, Tumor|Transcriptional Networks|Gene Expression Profiling|IL4I1 protein, human 121 rrad 30410449 Front Physiol 2018 PMC6209921 10.3389/fphys.2018.01498 0 0 0 621 Animals|*Aphids|*Peas|*Phloem|Buchnera|Symbiosis|Insect Proteins 121 rrad 30397133 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6255209 10.1073/pnas.1811024115 4 6 0 621 Calcium Channels, L-Type|Calcium Channels, N-Type|Monomeric GTP-Binding Proteins|Ion Channel Gating 121 rrad 30391675 Free Radic. Biol. Med. 2018 10.1016/j.freeradbiomed.2018.10.457 0 4 0 621 Humans|*Cellular Senescence|*Transcriptome Analysis|NF-kappa B|Fibroblasts|Tumor Suppressor Protein p53|*Biomarkers|Aging|Transcriptome|Reactive Oxygen Species|Cell Cycle Arrest|Transcriptional Activation|RRAD protein, human|ras Proteins 121 RTTN 30439596 Neurobiol. Aging 2018 10.1016/j.neurobiolaging.2018.10.012 1 0 0 72 Humans|Female|Animals|Mice|*Dopamine|*Cognition|Brain|Brain Mapping|Rest|Cognitive Dysfunction|Functional Magnetic Resonance Imaging|Neural Pathways|Aging|*Guided Imagery|Pituitary Gland|Hypothalamus|RXFP3 protein, human|Receptors, G-Protein-Coupled|SRD5A2 protein, human|Membrane Proteins|3-Oxo-5-alpha-Steroid 4-Dehydrogenase|rotatin protein, human 21 RTTN 30324028 PeerJ 2018 PMC6186407 10.7717/peerj.5759 0 1 0 72 Humans|Animals|Horses|*RNA|Sequence Analysis, RNA|High-Throughput Nucleotide Sequencing|Exome|Software|Gene Expression Profiling|Genetic Variation|Polymorphism, Single Nucleotide|*Asthma 21 RTTN 30168418 Elife 2018 PMC6141234 10.7554/eLife.37846 5 9 0 72 Humans|Animals|*Centrioles|*Microcephaly|Centrosome|Microtubule-Associated Proteins|Cell Cycle Proteins|Microtubules|Cell Cycle|Protein Binding|HeLa Cells 21 RTTN 30121372 Eur J Med Genet 2018 10.1016/j.ejmg.2018.08.001 1 0 0 72 Humans|*Polymicrogyria|*Microcephaly|Dwarfism|*Mutation|Homozygote|Nervous System Malformations|Pedigree|Encephalopathy|Brain|Carrier Proteins|Cell Cycle Proteins|Phenotype|Magnetic Resonance Imaging|Mutations, Missense|rotatin protein, human 21 RTTN 29967526 Pediatr. Res. 2018 PMC6258334 10.1038/s41390-018-0083-z 1 0 0 72 Infant|Humans|*Microcephaly|Pontocerebellar Hypoplasia|*Cerebellar Diseases|Dwarfism|*Seizures|Polymicrogyria|Brain|Cell Cycle Proteins|Carrier Proteins|Pedigree|Mutation|Intellectual Disability|rotatin protein, human 21 RTTN 29883675 Eur J Med Genet 2018 10.1016/j.ejmg.2018.06.001 1 1 0 72 Humans|*Microcephaly|*Nervous System Malformations|*Dwarfism|Colpocephaly|Brain Diseases|Polymicrogyria|Agenesis of Corpus Callosum|Pachygyria|Brain|Phenotype|Mutations|Lateral Ventricles|Carrier Proteins|Cell Cycle Proteins|Corpus Callosum 21 RTTN 29356416 Birth Defects Res 2018 10.1002/bdr2.1204 2 0 0 72 Microcephaly with Simplified Gyral Pattern|*Microcephaly|Dwarfism|Polymicrogyria|*Neuropathology|*Malformations of Cortical Development, Group II|Cell Cycle Proteins|Carrier Proteins|Phenotypes|Mutations|Brain|Pedigree|Seizures 21 S100A14 30422902 J. Acquir. Immune Defic. Syndr. 2018 PMC6331283 10.1097/QAI.0000000000001911 0 1 0 114 *Monocytes|*Natural Killer Cell|HIV-1|HIV Seronegativity|Substance Abuse, Intravenous|HIV Infections|*Plasma|*Cross Reactions 69 S100A14 30086514 Res. Vet. Sci. 2018 10.1016/j.rvsc.2018.07.006 0 0 0 114 Horses|Animals|*DNA Methylation|*B-DNA|Bovine papillomavirus 1|Skin Neoplasms|Horse Diseases|*Genes, cdc|Skin|Promoter Regions, Genetic|Epigenetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 69 S100A14 29858979 World J Pediatr 2018 10.1007/s12519-018-0163-5 1 0 0 114 Adult|Humans|Child|*S100 Protein Family|*Neonatology 69 S100A16 30558666 BMC Cancer 2018 PMC6296138 10.1186/s12885-018-5170-3 2 0 0 181 Humans|Female|*Prognosis|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Biomarkers, Tumor|S100 Proteins|Tumor Suppressor Protein p53|Kaplan-Meier Estimate|RNA, Messenger|Mutation|Apoptosis 46 S100A16 30405777 Oncol Lett 2018 PMC6202521 10.3892/ol.2018.9457 0 0 0 181 Humans|Breast Cancer 3|*Breast Neoplasms|Early Detection of Cancer|Prognosis|Gene Expression Regulation, Neoplastic|DNA Methylation|Gene Expression Profiling|Biomarkers, Tumor 46 S100A16 30183374 FASEB J. 2018 10.1096/fj.201800428R 3 1 0 181 Humans|*Small Cell Lung Carcinoma|*Exosomes|Endothelial Cells|*Up-Regulation|*Cell Survival|Lung Cancer|Carcinoma, Small Cell|Brain Neoplasms|*Brain|Cell Line, Tumor|*B-Lymphocytes, Regulatory|Prognosis|Gene Expression Regulation, Neoplastic|Signal Transduction|Coculture|Tumor Microenvironment|S100A16 protein, human|S100 Proteins 46 S100A16 30005139 Stem Cells 2018 10.1002/stem.2886 1 3 0 181 *Astrocytes|*Neurogenesis|Neural Stem Cell|Cell Differentiation|Nuclear Factor-1|Neuron, Dopamine|Glial Fibrillary Acidic Protein|Cells, Cultured|*Vitamin C|Activation, Transcriptional|STAT3 protein, human|STAT3 Transcription Factor|Promoter Regions, Genetic|DNA 46 S100A16 29928366 Oncol Lett 2018 PMC6004699 10.3892/ol.2018.8568 0 4 0 181 Female|Humans|Neoplasm Recurrence, Local|POU5F1 protein, human|*Octamer Transcription Factor-3|*Cancer Stem Cells|Nanog Homeobox Protein|Homeodomain Proteins|*Up-Regulation|Cell Line, Tumor|*Uterine Cervical Neoplasms|*Transcriptional Activation|NANOG protein, human|S100A16 protein, human|S100 Proteins 46 S100A16 29858979 World J Pediatr 2018 10.1007/s12519-018-0163-5 1 0 0 181 Adult|Humans|Child|*S100 Protein Family|*Neonatology 46 S100A16 29746588 PLoS ONE 2018 PMC5945035 10.1371/journal.pone.0197402 2 10 0 181 Humans|Animals|*Prognosis|Retrospective Studies|Lung Adenocarcinoma|*Adenocarcinoma|*Lung|Lung Neoplasms|Biomarkers, Tumor|DNA Methylation|Disease-Free Survival|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Gene Expression Profiling|Upregulation|DNA Copy Number Variations|S100 Protein Family|S100A16 protein, human 46 SALL3 30006568 Sci Rep 2018 PMC6045645 10.1038/s41598-018-28795-y 0 5 0 122 *DNA Methylation|Carcinoma, Renal Cell|Kidney Neoplasms|Von Hippel-Lindau Tumor Suppressor Protein|Gene Expression Regulation, Neoplastic|Gene Silencing|Promoter Regions, Genetic|*Hypoxia|Transcription Factors|Cell Line, Tumor|Mutation 61 SALL3 29854012 Clin Epigenetics 2018 PMC5975622 10.1186/s13148-018-0496-x 13 0 0 122 Humans|*Urinary Bladder Neoplasms|*DNA Methylation|*B-DNA|Cystoscopy|Biomarkers, Tumor|Neoplasm Recurrence, Local|*B-Lymphocytes 61 SALL3 29706459 Urol. Oncol. 2018 10.1016/j.urolonc.2018.04.001 3 0 0 122 Humans|*DNA Methylation|*Hematuria|*Prospective Studies|*Urinary Bladder|*Carcinoma, Transitional Cell|*Urologic Neoplasms|*Urinary Bladder Neoplasms|Cystoscopy|Biomarkers, Tumor|*Genetic Markers 61 SALL3 29602211 J Exp Zool A Ecol Integr Physiol 2018 10.1002/jez.2156 0 0 0 122 Animals|Female|Humans|*Transcription Factor 3|*Chickens|*Transcription Factors|*Eggs|Avian Proteins|TCF3 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Oviposition|*Phenotype|Single Nucleotide Polymorphisms|Genotype|Polymorphism, Single-Stranded Conformational|*Chinese 61 SALL3 29587736 BMC Urol 2018 PMC5870733 10.1186/s12894-018-0334-7 1 5 0 122 *Ureteral Neoplasms|*Kidney Pelvis|*Carcinoma, Transitional Cell|*Urologic Neoplasms|*Prognosis|Nephrectomy|Kidney Neoplasms|Neoplasm Recurrence, Local|Retrospective Studies|*Biomarkers|*Epigenetic|Epigenesis, Genetic 61 SALL3 29581773 J Cancer 2018 PMC5868161 10.7150/jca.23527 5 7 0 122 *Epigenesis, Genetic|Head and Neck Neoplasms|CpG Islands|DNA Methylation|Carcinoma, Squamous Cell|Promoter Regions, Genetic|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Disease-Free Survival 61 SALL3 29511085 J. Biol. Chem. 2018 PMC5925811 10.1074/jbc.RA117.000245 2 4 0 122 Humans|*Transcription Factor|*Downregulation|MCF-7 Cells|Gene Expression Regulation|*B Cells|Protein Isoforms|Cell Line, Tumor|Ribonucleoproteins|Cell Nucleus|shRNA 61 SAMD9L 30531146 Rinsho Ketsueki 2018 10.11406/rinketsu.59.2475 0 0 0 71 Humans|SAMD9 protein, human|Chromosome 7, monosomy|Chromosome Deletion|Myelocerebellar Disorder|Pancytopenia|*Malignancies, Hematological|Myelodysplastic Syndromes|Myeloproliferative Disorders|Tumor Suppressor Proteins|Intracellular Signaling Peptides and Proteins|Chromosome Aberrations|Cerebellar Ataxia|Pedigree|Mutations|Chromosome 7 43 SAMD9L 30211214 Int J Genomics 2018 PMC6120303 10.1155/2018/6582014 1 4 0 71 Humans|*Pheochromocytoma|*Whole Exome Sequencing|*Adrenal Gland Neoplasms|Paraganglioma|Succinate Dehydrogenase|*Oncogenes|Germ-Line Mutation|Mutation|Von Hippel-Lindau Tumor Suppressor Protein|Genetic Predisposition to Disease|*Germ Line 43 SAMD9L 30086151 PLoS ONE 2018 PMC6080784 10.1371/journal.pone.0201674 2 0 0 71 *Neutrophils|*Leukocytes, Mononuclear|Gene Ontology|Regulatory Network, Gene|*Sepsis|Bioinformatics|Protein Interaction Maps|Gene Expression Profiles|Gene Expression Profiling|Databases, Genetic|Signal Transduction|Transcription Factors|*White Blood Cells|Genes, cdc 43 SAMD9L 30047423 Hematol. Oncol. Clin. North Am. 2018 10.1016/j.hoc.2018.04.007 4 0 0 71 Adolescent|Child|Humans|Chromosome 7, monosomy|*Chromosomes, Human, Pair 7|*Myelodysplastic Syndromes|*Chromosome Deletion|Monosomy|Hematopoietic Stem Cell Transplantation|Phenotype 43 SAMD9L 30046003 JCI Insight 2018 PMC6124395 10.1172/jci.insight.121086 8 2 0 71 Humans|Monosomy 7 of Bone Marrow|Myelodysplastic Syndrome|Chromosome Deletion|SAMD9 protein, human|Leukemia, Myeloid, Acute|Chromosome 7, monosomy|Myeloproliferative Disorders|*Mutations|*Genetic Evolution|Tumor Suppressor Proteins|*Genes, Regulator|Intracellular Signaling Peptides and Proteins|*Germ Line|Allele|Chromosomes, Human, Pair 7 43 SAMD9L 29615405 Blood 2018 10.1182/blood-2017-12-822262 10 0 0 71 Humans|Mice|Animals|Chromosome 7, monosomy|*Chromosomes, Human, Pair 7|Comparative Genomic Hybridization|*Chromosome Deletion|Myeloproliferative Disorders|Myelodysplastic Syndromes|Chromosomal Aberrations|Tumor Suppressor Proteins|Haploinsufficiency|Intracellular Signaling Peptides and Proteins 43 SAMD9L 29535429 Leukemia 2018 PMC5940635 10.1038/s41375-018-0074-4 11 0 0 71 Humans|Adult|Child, Preschool|Child|Myelocerebellar Disorder|*Pancytopenia|SAMD9 protein, human|*Myeloproliferative Disorders|*Cerebellar Ataxia|Myelodysplastic Syndrome|*Genetic Predisposition to Disease|*Ataxia|Mutations, Germline|Tumor Suppressor Proteins|Chromosome Deletion|Intracellular Signaling Peptides and Proteins|*Genes, Regulator|Pedigree|Mutations|Neoplasms 43 SAMD9L 29447249 PLoS Pathog. 2018 PMC5831749 10.1371/journal.ppat.1006884 8 9 0 71 Humans|Mice|Animals|*Poxvirus Infection|Poxviruses|SAMD9 protein, human|Vaccinia virus|*Mammals|Virus Replication|Viral Proteins|Host Range|Amino Acid Sequence|Intracellular Signaling Peptides and Proteins|Cell Lines|Host-Pathogen Interactions|Virulence 43 SBSN 30019072 Knee Surg Sports Traumatol Arthrosc 2018 10.1007/s00167-018-5057-5 0 0 0 57 *Hamstring Muscles|Hamstring Tendons|Anterior Cruciate Ligament Reconstruction|Anterior Cruciate Ligament Injuries|Tissue and Organ Harvesting|Peripheral Nerve Injuries|Incidence|Dermatologic Surgical Procedures|Peripheral Nervous System|Afferent Pathways 23 SBSN 29301256 Molecules 2018 PMC6017464 10.3390/molecules23010088 2 0 0 57 *Esophageal Squamous Cell Carcinoma|Esophageal Cancer|*Tumorigenesis|Carcinoma, Squamous Cell|*Cell Transformation, Neoplastic|Neoplasm Proteins|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Networks, Gene 23 SCAF1 30426551 Immunol. Cell Biol. 2018 10.1111/imcb.12217 2 0 0 104 Humans|*Macrophages|*Phagocytosis|Monocytes|*Sclerosis, Systemic|Apoptosis|Fibrosis|Inflammation|Flow Cytometry|Cell Differentiation 28 SCAF1 29787824 Gene 2018 10.1016/j.gene.2018.05.044 2 0 0 104 Humans|*Sequencing, Next-Generation|Alternative Splicing|SRSF1 protein, human|Serine-Arginine Splicing Factors|Exons|Isoforms|Bioinformatic|OF-1 protein|*DNA-Binding Proteins|mRNA|*gamma-Synuclein|Cloning, Molecular|Cell Line, Tumor|Nested PCR|SCAF1 protein, human 28 Scara3 30118734 Dev. Comp. Immunol. 2018 10.1016/j.dci.2018.08.010 2 0 0 1145 Animals|*Type I Interferon|*Scavenger Receptors, Class A|*Chinook Salmon|*Spleen|*RNA, Double-Stranded|*Cell Line|Immunity, Innate|RNA, Viral|Poly I-C|Antiviral Agents|Protein Binding 37 Scara3 29705808 Cell. Physiol. Biochem. 2018 10.1159/000489370 1 5 0 1145 Humans|Male|Mice|Animals|*Prostate|*Sumoylation|Prostate Cancers|Cell Line, Tumor|Scavenger Receptors, Class A|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Death|Heat-Shock Proteins|Cysteine Endopeptidases|Oncogenesis|Senp1 protein, mouse|Endopeptidases 37 Scara3 29471060 Fish Shellfish Immunol. 2018 10.1016/j.fsi.2018.02.029 2 0 0 1145 Animals|*Oncorhynchus mykiss|*Scavenger Receptors, Class A|Fish Proteins|Immunity, Innate|Fish Diseases|Gene Expression Regulation|Transcript Expression Analysis|Sequence Alignment|Amino Acid Sequence|Phylogeny|Cell Line 37 SCGB1D2 29588598 Onco Targets Ther 2018 PMC5858829 10.2147/OTT.S155367 2 8 0 18 Humans|podocalyxin|*Pancreatic Cancer|CA-19-9 Antigen|*Sialoglycoproteins|Biomarkers, Tumor|Kaplan-Meier Estimate|ROC Curve 156 SCPEP1 30397354 Nat. Med. 2018 PMC6223318 10.1038/s41591-018-0230-4 4 2 0 445 Humans|MCF-7 Cells|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Proliferation|Cell Movement|*Disease Progression|*B Cells|Extracellular Vesicles|Small Noncoding RNA 47 SCPEP1 30026265 Biol Open 2018 PMC6124576 10.1242/bio.033282 7 1 0 445 Mice|Cattle|Animals|*Embryo, Mammalian|Embryonic Stem Cells|Pluripotent Stem Cells|Blastocyst|Gene Expression Regulation, Developmental|Transcriptome 47 SCRN1 30120715 Endocr. Pathol. 2018 10.1007/s12022-018-9543-6 2 0 0 65 Humans|*Whole Exome Sequencing|Phosphatidylinositol 3-Kinases|Thyroid cancer, medullary|*Carcinoma, Neuroendocrine|*Thyroid Cancer|Carcinoma, Medullary|Proto-Oncogene Proteins c-ret|Exome|*Asian Continental Ancestry Group|Illumina Sequencing|Mutations|MicroRNAs|Signal Transduction|Taiwan|SCRN1 protein, human|Nerve Tissue Proteins|KLHL25 protein, human|Carrier Proteins 21 SDHAF2 30536464 J. Intern. Med. 2018 10.1111/joim.12869 4 0 0 134 Humans|Child|*Pheochromocytoma|Magnetic Resonance Imaging|Whole Body Imaging|*Paraganglioma|*Adrenal Gland Neoplasms|*Genetic Testing|Germ-Line Mutation|Genetic Predisposition to Disease 125 SDHAF2 30484866 Laryngoscope 2018 10.1002/lary.27509 0 0 0 134 *Paraganglioma|Succinate Dehydrogenase|Pheochromocytoma|Adrenal Gland Neoplasms|Germ-Line Mutation|Iron-Sulfur Proteins|Genetic Testing|Pedigree|Mutation|Membrane Proteins|Head and Neck Neoplasms|Protein Subunits|Mutation, Missense|*Neck 125 SDHAF2 30405919 Case Rep Endocrinol 2018 PMC6204204 10.1155/2018/6358485 2 0 0 134 *Pheochromocytoma|*Thyroid Cancer, Papillary|*Paraganglioma|*Adrenal Gland Neoplasms|*Mutation|Germ-Line Mutation|Genetic Predisposition to Disease|Thyroid Neoplasms 125 SDHAF2 30356369 Case Rep Endocrinol 2018 PMC6176301 10.1155/2018/2091257 1 0 0 134 Female|Humans|Young Adult|Adult|*Pheochromocytoma|*Adrenal Gland Neoplasms|Paraganglioma|Succinate Dehydrogenase|*Cyanosis|Germ-Line Mutation|Genetic Testing|Mutation|Heart Defects, Congenital|*Hypoxia 125 SEC14L2 30472319 J. Hepatol. 2018 10.1016/j.jhep.2018.11.012 1 0 0 336 *Hepatitis C virus|*Binding Protein|*Hepatitis C|*Genotype|Virus Replication|Replicon|Antiviral Agents|Cell Line|Hepatocytes|Cell Culture|*Lipids 55 SEC14L2 29605316 J. Dairy Sci. 2018 10.3168/jds.2017-13630 0 0 0 336 Pregnancy|Cattle|Animals|Female|*Peripartum Period|*Tocopherol|Lactation|Milk|*Liver|*Vitamin E|Eating|Parturition|Biopsy 55 SEC14L2 29549787 Virology 2018 10.1016/j.virol.2018.03.001 2 0 0 336 *5' Untranslated Regions|*Hepacivirus|*Nucleotides|Viral Nonstructural Proteins|*Substitutions, Amino Acid|Hepatitis C|Genotype|Virus Replication|RNA, Viral|Mutations|daclatasvir|Imidazoles|Amino Acids 55 SERPINA6 30058887 Expert Rev Endocrinol Metab 2018 10.1080/17446651.2017.1332991 2 2 0 697 *Transcortin|ELANE protein, human|Neutrophil Elastase|*Inflammation|Cortisol|Severe Sepsis 94 SERPINA6 30029587 Physiol. Genomics 2018 PMC6230873 10.1152/physiolgenomics.00058.2018 0 0 0 697 Male|Humans|Female|*Proteome|*Brain Ischemia|*Stroke|Corticosteroid Binding Globulin|*Adrenal Cortex Hormones|Cortisol|*Signal Transduction|Protein Binding|Proteomics|Sex Differences 94 SERPINA6 29949718 Am. J. Respir. Cell Mol. Biol. 2018 PMC6236690 10.1165/rcmb.2018-0088OC 6 0 0 697 Humans|Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|White|Smoking|Lung|*Sequencing, Whole Genome|Case-Control Studies|African Americans|Boston 94 SERPINA6 29679879 Psychoneuroendocrinology 2018 10.1016/j.psyneuen.2018.04.009 1 0 0 697 Adult|Child|Humans|*Hypothalamo-Hypophyseal System|*Pituitary-Adrenal System|Cortisol|Corticosteroid Binding Globulin|*Multifactorial Inheritance|Saliva|Stress, Psychological|Circadian Rhythm|Polymorphism, Single Nucleotide|SERPINA1 protein, human|alpha 1-Antitrypsin 94 SERPINA6 29408990 Biol. Reprod. 2018 PMC6692846 10.1093/biolre/ioy031 3 0 0 697 Male|Mice|Animals|*Testis|*Leydig Cells|Seminiferous Epithelium|Spermatogenesis|Sertoli Cells|*Polysomes|Testosterone|Meiosis|Blood-Testis Barrier 94 SERPINA6 29307512 Mol Metab 2018 PMC5985049 10.1016/j.molmet.2017.12.007 14 22 0 697 Humans|Insulin Secretion|Insulin-Secreting Cells|*Cell Line|Insulin|Glucose|Signal Transduction|Apoptosis 94 SERPINB5 30257383 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.08.100 11 3 0 751 Humans|Female|Animals|*Phytoestrogens|*Isoflavones|coumestan|*Stilbenes|*Lignans|*Coumarins|Estrogen Receptors|Estrogens|Antineoplastic Agents, Phytogenic|Oestradiol|Cell Proliferation|Signal Transduction|Cell Cycle 102 SERPINB5 29675033 Front Genet 2018 PMC5895731 10.3389/fgene.2018.00108 14 31 0 751 Humans|*Prognosis|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Immunohistochemistry|Biomarkers, Tumor|Pancreas|Gene Expression Regulation, Neoplastic|Transcriptomes|Pancreatitis 102 SERPINB5 29511373 Int J Med Sci 2018 PMC5835708 10.7150/ijms.22823 1 9 0 751 102 SERPINB7 30592269 Mol Med Rep 2018 PMC6390042 10.3892/mmr.2018.9782 0 2 0 30 Humans|Mice|Animals|*Keratinocytes|*Transcriptome|Epidermis|Psoriasis|Skin|Epidermal Cells|Gene Expression Profiling|RNA, Messenger|Intercellular Signaling Peptides and Proteins|SERPINB7 protein, human|Serpins 57 SERPINB7 30581033 Ann Dermatol Venereol 2018 10.1016/j.annder.2018.11.005 0 0 0 30 Humans|Female|*Keratoderma, Palmoplantar|*Keratoderma, Palmoplantar, Diffuse|Pedigree|Chinese|Serpins|Mutation|Europe|France 57 SERPINB7 30452289 Genet Test Mol Biomarkers 2018 10.1089/gtmb.2018.0154 0 0 0 30 Humans|*Pedigree|Palmoplantar Keratoderma, Nonepidermolytic|*Keratoderma, Palmoplantar, Diffuse|Keratin-9|*Mutation|*Chinese|Keratoderma, Palmoplantar|Heterozygote|KRT1 protein, human|Keratin-1 57 SERPINB7 30245304 Transl Oncol 2018 PMC6149193 10.1016/j.tranon.2018.08.019 1 0 0 30 Humans|gemcitabine|*Deoxycytidine|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|130-nm albumin-bound paclitaxel|Paclitaxel|Albumins|Antineoplastic Combined Chemotherapy Protocols|*Pancreas|Adenocarcinoma|Disease-Free Survival|SERPINB7 protein, human|Serpins 57 SERPINB7 29579455 J. Invest. Dermatol. 2018 10.1016/j.jid.2017.12.008 2 0 0 30 Prospective Studies|Palmoplantar Keratosis|gentamicin B|*Gentamycin|Nonsense Mutations|Mutation|Serpins 57 SERPINB7 29489036 J Eur Acad Dermatol Venereol 2018 10.1111/jdv.14902 4 0 0 30 *Palmoplantar Keratodermas|Desmoglein 1|Pedigree|Genetic Predisposition to Disease|*Syndromes|Mutation|Epidermis|*Chromosome Structures 57 SERPINB9 30582855 Probl Radiac Med Radiobiol 2018 10.33145/2304-8336-2018-23-331-350 0 0 0 198 Humans|*Ionizing Radiation|Radiation Exposure|Chernobyl Nuclear Accident|Radiation Dosage|Radiation Injuries|Occupational Exposure|Emergency Responders|Radiation Monitoring|*Biological Markers|Case-Control Studies|Gene Expression 133 SERPINB9 30127393 Nat. Med. 2018 PMC6487502 10.1038/s41591-018-0136-1 77 2 0 198 Humans|Animals|CTLA4 protein, human|CTLA-4 Antigen|*Immunotherapy|CD274 protein, human|B7-H1 Antigen|Lymphocytes, Tumor-Infiltrating|Programmed Cell Death 1 Receptor|Cytotoxic T-Lymphocytes|Antineoplastic Agents, Immunological|CD8-Positive T-Lymphocytes|Melanoma, Experimental|Tumor Microenvironment|Antibodies, Monoclonal|T-Lymphocytes, Regulatory|Cell Line, Tumor 133 SERPINB9 29996948 Arthritis Res. Ther. 2018 PMC6042324 10.1186/s13075-018-1640-x 3 0 0 198 Humans|*RNA, Long Noncoding|*Monocytes|*Lupus Erythematosus, Systemic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Transcriptome|RNA, Messenger|Dendritic Cells 133 SERPINB9 29967939 Acta Neuropathol. 2018 PMC6280657 10.1007/s00401-018-1881-4 11 0 0 198 Female|Male|*Alzheimer Disease|Genome-Wide Association Study|Amyloid beta-Peptides|tau Proteins|*Biomarkers|Peptide Fragments|Plaque, Amyloid|Apolipoproteins E|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Endophenotypes|Phosphorylation 133 SERPINB9 29507647 Clin Epigenetics 2018 PMC5833080 10.1186/s13148-018-0460-9 7 13 0 198 Abdominal Aorta|Aneurysm, Abdominal Aortic|DNA Methylation|Epigenesis, Genetic|Muscle, Smooth, Vascular|Myocytes, Smooth Muscle 133 SERPINI1 30194604 Methods Mol. Biol. 2018 10.1007/978-1-4939-8645-3_15 3 1 0 165 Rats|Animals|neuroserpin|*Serpins|*Neuroprotection|SERPINE1 protein, human|PAI-1|Injury, Spinal Cord|Anti-Inflammatory Agents|Inflammation|Neuropeptides|PLAT protein, human|Tissue-Type Plasminogen Activator|Serine Endopeptidases|Subdural Space|Disease Models, Animal|Neuroprotective Effects|Spinal Cord 31 SERPINI1 30194596 Methods Mol. Biol. 2018 10.1007/978-1-4939-8645-3_7 1 1 0 165 Familial encephalopathy with neuroserpin inclusion bodies|Heredodegenerative Disorders, Nervous System|neuroserpin|Neuropeptides|Epilepsies, Myoclonic|SERPINA1 protein, human|alpha 1-Antitrypsin|Polymerization|Protein Degradation|Endoplasmic Reticulum|Mutations|Cells, Cultured|*B Cells 31 SERPINI1 30194076 Cancer Genomics Proteomics 2018 PMC6199573 10.21873/cgp.20094 3 2 0 165 *Histone Deacetylase Inhibitors|trichostatin A|*Transcriptome|BRAF protein, human|Proto-Oncogene Proteins B-raf|*Hydroxamic Acids|Melanoma, Cutaneous Malignant|Malignant Melanoma|Skin Neoplasms|Drug Resistance, Neoplasm|Protein Kinase Inhibitors|Cell Line, Tumor|Histone Deacetylases|MAP Kinase Signaling System|Mutation|Gene Expression Regulation, Neoplastic|*Molecular Targeted Therapy 31 SERPINI1 30049290 Acta Neuropathol Commun 2018 PMC6062993 10.1186/s40478-018-0573-6 1 7 0 165 Humans|Rats|Animals|*Chromatin Immunoprecipitation Sequencing|*DNA Damage|DNA Repair|Chromatin|*Neurons|Cell Nucleus|Ionizing Radiation|Histones|DNA-Binding Proteins|EPM2A protein, human|Protein Tyrosine Phosphatases, Non-Receptor 31 SERPINI1 29885422 Neuropharmacology 2018 PMC6310223 10.1016/j.neuropharm.2018.06.004 1 5 0 165 Pregnancy|Male|Female|Animals|Rats|*Astrocytes|*Ethanol|PLAT protein, human|Tissue-Type Plasminogen Activator|Fetal Alcohol Spectrum Disorders|Cells, Cultured|Upregulation|Coculture Techniques|Neuronal Plasticity|Plasminogen Activator Inhibitor 1|Hippocampus|Brain|Animals, Newborn|*Homeostasis|Plasminogen 31 SETD5 30523388 Curr. Genet. 2018 PMC6511328 10.1007/s00294-018-0917-6 1 0 0 181 *Saccharomyces cerevisiae|*PR-SET Domains|Saccharomyces cerevisiae Proteins|Chromatin|*Yeast, Dried|Gene Expression Regulation, Fungal|SET protein, human|Histone Chaperones|Histones|Chromosomal Proteins, Non-Histone|Genes, Fungal|Transcription, Genetic|Stress, Physiological|Stability, Genome|Transcription Factors|Set3 protein, S cerevisiae|Histone Deacetylases 41 SETD5 30458291 Gene 2018 10.1016/j.gene.2018.11.046 4 1 0 181 Male|Animals|Mice|*Histones|*Methylation|Epigenesis, Genetic|Set2 protein, human|Histone-Lysine N-Methyltransferase|SETD1B protein, human|NSD2 protein, human|KMT2A protein, human|KDM1A protein, human|Histone Demethylases|*Cyprinodontiformes|*Self-Fertilizations|PRDM2 protein, human|KDM5C protein, human|Embryonic Development|*Killifishes|*Reproduction|KMT2D protein, human 41 SETD5 30455454 Nat. Neurosci. 2018 10.1038/s41593-018-0266-2 8 2 0 181 Humans|Animals|Mice|*Intellectual Disability|*Haploinsufficiency|Autism Spectrum Disorder|*Gene Expression|*Cognition|Mutations|Chromosome Deletion|Phenotype|Methyltransferases|Genes, Developmental|SETD5 protein, human 41 SETD5 30280788 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201809_15940 0 6 0 181 PTEN protein, human|*PTEN Phosphohydrolase|*Stroke|Phosphatidylinositol 3-Kinases|Long Non-Coding RNA|Proto-Oncogene Proteins c-akt|MicroRNAs|Signal Transduction|Apoptosis|Cell Proliferation|Reperfusion Injury|*Cell Death|Neurons 41 SETD5 30190612 Genet. Med. 2018 PMC6405313 10.1038/s41436-018-0266-3 24 0 0 181 Humans|*Phenotypes|DNA Copy Number Variations|*Genetic Background|Intellectual Disability|Sequence Deletion|Siblings|Cognition 41 SETD5 32595297 Soa Chongsonyon Chongsin Uihak 2018 PMC7298899 10.5765/jkacap.2018.29.2.62 0 0 0 181 Child|Adolescent|Humans|Genome-Wide Association Study|*Attention Deficit Disorder with Hyperactivity|Republic of Korea|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Quantitative Trait Locus|Phenotype|Case-Control Studies 41 SETD5 29484850 Dev Neurobiol 2018 10.1002/dneu.22584 2 3 0 181 Humans|Male|Female|*Autistic Disorder|Intellectual Disability|Phenotype|Mutation|Heterozygote|Chromosome Deletion|Autism Spectrum Disorders|Penetrance|Methyltransferases|Syndrome|SETD5 protein, human 41 SETMAR 30458291 Gene 2018 10.1016/j.gene.2018.11.046 4 1 0 173 Male|Animals|Mice|*Histones|*Methylation|Epigenesis, Genetic|Set2 protein, human|Histone-Lysine N-Methyltransferase|SETD1B protein, human|NSD2 protein, human|KMT2A protein, human|KDM1A protein, human|Histone Demethylases|*Cyprinodontiformes|*Self-Fertilizations|PRDM2 protein, human|KDM5C protein, human|Embryonic Development|*Killifishes|*Reproduction|KMT2D protein, human 44 SETMAR 30329085 Nucleic Acids Res. 2018 PMC6326780 10.1093/nar/gky937 5 0 0 173 Animals|Humans|*Methylase, Histone|*Histones|*Transcriptome|Transposase|Histone-Lysine N-Methyltransferase|DNA-Binding Proteins|Transcription Factors|Methylation|DNA Transposable Elements|Protein Domains|Primate 44 SETMAR 29294071 Mol. Biol. Evol. 2018 10.1093/molbev/msx322 14 7 0 173 Humans|Cattle|Animals|*Genome|Breeding|Genetics, Population|Genotype|Hybridization, Genetic|Phenotypes|Polymorphism, Single Nucleotide|*Chinese|China|ERCC2 protein, human|Xeroderma Pigmentosum Group D Protein|MAPK7 protein, human|Mitogen-Activated Protein Kinase 7 44 SEZ6L 29979789 PLoS ONE 2018 PMC6034874 10.1371/journal.pone.0200344 3 9 0 15 Humans|Animals|Mice|Infant|*Amyloid Precursor Protein Secretases|*Aspartic Acid Endopeptidases|*Niemann-Pick Disease, Type C|Amyloid beta-Protein Precursor|Alzheimer Disease|Neurons|Hippocampus|Brain|Cerebellum|Proteolysis|Lysosomes|Endosomes|BACE1 protein, human|Bace1 protein, mouse|Sez6 protein, mouse|Nerve Tissue Proteins 21 SEZ6L 29716987 Mol. Cell Proteomics 2018 PMC6072545 10.1074/mcp.RA118.000608 3 0 0 15 Animals|Mice|*Amyloid Precursor Protein Secretases|*Aspartic Acid Endopeptidases|*Biotinylation|*Click Chemistry|APLP1 protein, human|Amyloid beta-Protein Precursor|Alzheimer Disease|Neurons|*Cell Membrane|Nerve Tissue Proteins|Mice, Knockout|Proteolysis|Proteome|Membrane Proteins|Brain|Chl1 protein, mouse|Cell Adhesion Molecules|Bace1 protein, mouse 21 SFMBT2 30510446 Cancer Manag Res 2018 PMC6248399 10.2147/CMAR.S172592 19 2 0 127 *Stomach Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Stomach|Cell Line, Tumor|Oncogenes|circRNAs|Signal Transduction|Disease Progression 46 SFMBT2 30272322 Int. J. Mol. Med. 2018 10.3892/ijmm.2018.3894 1 4 0 127 Humans|*Chondrocytes|Hedgehog Proteins|Chondrogenesis|SOX9 Transcription Factor|Collagen Type II|Cell Differentiation|Cartilage, Articular|Osteoarthritis|Upregulation|Cells, Cultured|Signal Transduction|Cell Proliferation|SOX9 protein, human 46 SFMBT2 30133133 J. Cell. Mol. Med. 2018 PMC6201222 10.1111/jcmm.13826 1 14 0 127 Humans|*Downregulation|Chondrocytes|Articular Cartilage|MMP13 protein, human|Matrix Metalloproteinase 13|Osteoarthritis, Knee|SOX9 Transcription Factor|Knee Joint|NF kB|Interleukin-1beta|siRNA|Tumor Necrosis Factor-alpha|Cells, Cultured 46 SFMBT2 30079806 Epigenetics 2018 PMC6224209 10.1080/15592294.2018.1507199 4 0 0 127 Animals|Mice|Female|Pregnancy|*Trophoblasts|*Nuclear Transfer Techniques|Cloning, Organism|Placental Development|Placenta|Genomic Imprinting|DNA Methylation|Gene Expression Regulation, Developmental|Transcription Factors|GAB1 protein, human|Adaptor Proteins, Signal Transducing|Stem Cells|Sfmbt2 protein, mouse 46 SFMBT2 30070359 Int. J. Cancer 2018 10.1002/ijc.31778 4 0 0 127 Humans|*Human Papilloma Virus|*Squamous Cell Carcinoma of Head and Neck|*Papillomavirus Infections|*Oropharyngeal Neoplasms|Cyclin-Dependent Kinase Inhibitor p16|Carcinoma, Squamous Cell|*Mouth Neoplasms|DNA Methylation|DNA, Viral|Biomarkers, Tumor|Head and Neck Neoplasms|ELMO1 protein, human|Adaptor Proteins, Signal Transducing|Mirn129 microRNA, human|MicroRNAs 46 SFMBT2 29775793 Clin. Gastroenterol. Hepatol. 2018 PMC6368476 10.1016/j.cgh.2018.05.004 0 1 0 127 Humans|*DNA Methylation|*Colorectal Cancer|*Inflammatory Bowel Disease|*Colonic Neoplasms|Colitis, Ulcerative|Colonoscopy|Feces|Crohn's Disease|Biomarkers, Tumor|*Hyperplasia|*Body Fluids 46 SFMBT2 29669510 Bosn J Basic Med Sci 2018 PMC5988534 10.17305/bjbms.2018.2800 2 0 0 127 Humans|*RNA, Long Noncoding|Epigenesis, Genetic|*Hepatitis B|Liver Cancer|Carcinoma, Hepatocellular|B virus, Hepatitis|Hepatitis B Surface Antigens|Hepatitis B, Chronic|Hepatitis B e Antigens|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|Gene Expression Profiling|Prognosis 46 SFMBT2 29506130 Biol. Reprod. 2018 PMC5991201 10.1093/biolre/ioy050 0 1 0 127 Animals|Male|Humans|Epigenesis, Genetic|*Epigenetic|DNA Methylation|*Psychological Stress|Modifications, Histone|Sperm|Heredity|Phenotype|miRNA|*B-Lymphocytes|Mammals|*Fathers 46 SGCA 30485132 FASEB J. 2018 10.1096/fj.201801714R 0 0 0 379 Myosin Heavy Chain|Muscle Fibers, Skeletal|*Muscular Diseases|Muscle Contraction|Muscular Dystrophies|Muscle, Skeletal|Isoforms 116 SGCA 30218921 J. Neurol. Sci. 2018 10.1016/j.jns.2018.08.026 1 0 0 379 Sarcoglycanopathies|Sarcoglycans|Muscular Dystrophies, Limb Girdle|DNA Mutational Analysis|Mutations|Phenotype|Muscle, Skeletal 116 SGCA 30056071 Gene 2018 10.1016/j.gene.2018.07.067 1 0 0 379 Limb-girdle muscular dystrophy type 2A|Iran|*Muscular Dystrophies, Limb Girdle|Calpain|Homozygote|Muscle Proteins|Mutations|Pedigree 116 SGCD 30485132 FASEB J. 2018 10.1096/fj.201801714R 0 0 0 100 Myosin Heavy Chain|Muscle Fibers, Skeletal|*Muscular Diseases|Muscle Contraction|Muscular Dystrophies|Muscle, Skeletal|Isoforms 88 SGCD 30257524 Genes (Basel) 2018 PMC6210939 10.3390/genes9100467 1 0 0 100 88 SGCD 30247079 Int. J. Radiat. Biol. 2018 10.1080/09553002.2018.1516908 3 0 0 100 88 SGCD 30216109 FASEB J. 2018 PMC6338641 10.1096/fj.201800622RR 7 1 0 100 Mice|Animals|CCN2 protein, human|*Connective Tissue Growth Factor|*Muscle, Skeletal|Dystrophy, Muscular|*Extracellular Matrix|Fibrosis|Knockout Mouse|Disease Models, Animal|Signal Transduction 88 SGCD 30143409 Nutr Metab Cardiovasc Dis 2018 10.1016/j.numecd.2018.06.019 0 0 0 100 Mice|Animals|*Cardiomyopathy, Dilated|*Catechin|*Sarcoglycans|*Mice, Knockout|Ventricular Remodeling|Myocardium|Ventricular Function, Left|Atrial Natriuretic Factor|Myocytes, Cardiac|Heart Failure|Natriuretic Peptide, Brain|Disease Models, Animal|Fibrosis 88 SH3PXD2B 30088855 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40386 0 0 0 105 Humans|Child|Female|KBG syndrome|*Coccyx|*Facies|*Tooth Abnormalities|*Bone Diseases, Developmental|Jarcho-Levin syndrome|*Abnormalities, Multiple|*Intellectual Disability|Phenotype|Chromosome Deletion|Genetic Association Studies|Mutations|Heterozygote|Dwarfism|Comparative Genomic Hybridization|Sequencing, Whole Exome|Repressor Proteins|Hernia, Diaphragmatic 23 SHROOM2 30179680 Gene 2018 10.1016/j.gene.2018.08.051 0 0 0 47 Swine|Animals|Chromosome Mapping|DNA Copy Number Variations|Genomics|INDEL Mutation|High-Throughput Nucleotide Sequencing|Sequence Analysis, DNA|Breeding|Molecular Sequence Annotation|Quantitative Trait Loci|Genotype|Single Nucleotide Polymorphisms|Phenotypes|Computational Biology|Base Sequence 26 SHROOM2 30160833 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.38836 1 1 0 47 Male|Humans|Ocular Albinism type 1|*Albinism, Ocular|Genetic Diseases, X-Linked|Eye Proteins|Pedigree|Mutations|Membrane Glycoproteins|Eyes|Gene Deletion|*Hearing Loss, Sensorineural|Deafness|*Infertility|GPR143 protein, human 26 SHROOM2 29426343 Part Fibre Toxicol 2018 PMC5807760 10.1186/s12989-018-0244-6 4 15 0 47 Humans|*DNA Methylation|Nanotubes, Carbon|Epigenesis, Genetic|Bronchi|Epithelial Cells|DNA Damage|Cell Line|DNA|Lung|Particle Size|*Cell Nucleus 26 SHROOM2 29423651 Hum. Genet. 2018 PMC5876139 10.1007/s00439-017-1864-x 2 11 0 47 Humans|Animals|*Neural Tube Defect|Anencephaly|Spina Bifida|*Cohort Studies|Genetic Predisposition to Disease|Mutation|*Chinese|Sequencing, Next-Generation 26 SIDT2 30382898 Hum. Genomics 2018 PMC6211397 10.1186/s40246-018-0180-4 0 4 0 73 *Metabolic Syndrome|Genome-Wide Association Study|Diabetes Mellitus, Type 2|Republic of Korea|*Genotype-Phenotype Association|Single Nucleotide Polymorphism|Genotype|Genetic Predisposition to Disease|Phenotype|Cardiovascular Disease|Risk Factor 25 SIDT2 29896245 Exp Ther Med 2018 PMC5995057 10.3892/etm.2018.6187 1 3 0 73 Mice|Animals|*Lipid Metabolism|*Lysosomes|*Intracellular Membranes|Membrane Proteins|Nucleotide Transport Proteins|Autophagy|Liver|Disease Models, Animal|Sidt2 protein, mouse 25 SIDT2 29752955 Metab. Clin. Exp. 2018 10.1016/j.metabol.2018.05.004 0 0 0 73 Mice|Animals|*Dystrophy, Muscular|*Muscle, Skeletal|*Phenotype|Knockout Mouse|Integral Membrane Protein|Lysosomes|Autophagy|Insulin Secretion|Sidt2 protein, mouse 25 SIDT2 29404214 PeerJ 2018 PMC5793713 10.7717/peerj.4314 2 3 0 73 Genome-Wide Association Study|*Study, Genetic Association|*Lipids|*Phenotype|Polymorphism, Single Nucleotide|Triglycerides|Philippines|Nigeria 25 SIDT2 29363559 J. Lipid Res. 2018 PMC5832936 10.1194/jlr.M073817 2 0 0 73 *Lipid Metabolism|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Autophagy|Lysosomes|Hepatocytes|Non-alcoholic Fatty Liver Disease|Liver|Integral Membrane Protein|Cells, Cultured 25 Sigmar1 30371279 J Am Heart Assoc 2018 PMC6474981 10.1161/JAHA.118.009775 3 0 0 1064 Animals|Mice|*Knockout Mouse|*Mitochondrial Dynamics|Mitochondria, Heart|*Heart Diseases|*Bioenergetics|Myocardial Contraction|Myocytes, Cardiac|sigma-1 receptor|*Receptors, sigma|Myocardium|Heart Failure|Oxygen Consumption|Oxidative Stress|Signal Transduction|Hemodynamics 92 Sigmar1 30266269 J Pain 2018 10.1016/j.jpain.2018.08.011 1 0 0 1064 Humans|sigma-1 receptor|*Pain, Neuropathic|*Receptors, sigma|Hyperalgesia, Thermal|Pain Threshold|*Phenotype|Pain Measurement|Genotype|Physical Stimulation 92 Sigmar1 30079398 Acta Myol 2018 PMC6060428 2 0 0 1064 92 Sigmar1 29674970 Front Pharmacol 2018 PMC5895707 10.3389/fphar.2018.00330 5 21 0 1064 *Banisteriopsis|*Hallucinogens|*Epigenetic Process|*Memory|Fear|Stress Disorders, Post-Traumatic|sigma-1 receptor|*Receptors, sigma 92 Sigmar1 29614681 J. Alzheimers Dis. 2018 10.3233/JAD-171001 0 2 0 1064 Animals|Mice|*Fluvoxamine|Secretase|Amyloid Protein Precursor|*Memory|Amyloid beta-Peptides|Alzheimer Disease|Peptide Fragments|*Amyloidogenic Proteins|*Amyloidosis|Neurons|Disease Models, Animal|Brain|Cognition 92 Sigmar1 29593724 Front Immunol 2018 PMC5854644 10.3389/fimmu.2018.00463 2 67 0 1064 Humans|*Leprosy|Mycobacterium leprae|MicroRNAs|mRNA|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Expression|Phagocytosis 92 SIM2 30531838 Oncogene 2018 PMC6450754 10.1038/s41388-018-0622-4 0 8 0 147 *Epithelial-Mesenchymal Transition|*Ataxia-Telangiectasia|BRCA1 protein, human|BRCA1 Protein|*Homologous Recombination|DNA Repair|Ductal Carcinoma In Situ|Rad51 Recombinase|DNA Damage|Ataxia Telangiectasia Mutated Proteins|CDH1 protein, human|E Cadherin|Genomic Instability|Cell Line, Tumor|Transcription Factors|Phosphorylation|Antigens, CD 122 SIM2 30447446 World Neurosurg 2018 10.1016/j.wneu.2018.11.030 3 0 0 147 Humans|*Radial Artery|*Wrist|Endovascular Procedures|Angiograms|Puncture 122 SIM2 30259787 Per Med 2018 10.2217/pme-2017-0091 5 0 0 147 *Carcinoma, Renal Cell|Kidney Neoplasms|Gene Regulatory Networks|Biomarkers, Tumor|Gene Expression Profiling|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Transcriptome|Computational Biology|Software 122 SIM2 29964097 Gene 2018 10.1016/j.gene.2018.06.096 0 4 0 147 Humans|*RNA, Long Noncoding|Caco-2 Cells|*Colorectal Cancer|HCT 116 Cells|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|*Disease Progression|Epithelial-Mesenchymal Transition|Upregulation|Wnt Signaling Pathway|Cell Line, Tumor|HT29 Cells|*Neoplastic Processes|*Colonic Neoplasms|SIM2 protein, human|Basic Helix-Loop-Helix Transcription Factors 122 SIM2 29869716 Cell Tissue Res. 2018 10.1007/s00441-018-2859-1 5 0 0 147 Rats|Mice|Animals|*Hypothalamus|*Neuroendocrine System|*Neurons|Supraoptic Nucleus|Paraventricular Hypothalamic Nucleus|transcription factor Brn-2|Homeodomain Proteins|Pituitary Gland, Posterior|POU Domain Factors|Arcuate Nucleus|Medial Eminence|Axons|*Mammals|Transcription Factors|Sim1 protein, mouse|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Dbx1 protein, mouse 122 SIM2 29735542 Cancer Res. 2018 PMC6386530 10.1158/0008-5472.CAN-17-3091 4 5 0 147 Humans|*Leukemia, Promyelocytic, Acute|*Antineoplastic Agents|*Cell Proliferation|5-Methylcytosine|DNA-Binding Proteins|Dioxygenases|Proto-Oncogene Proteins|DNA Methylation|DNA Demethylation|Promoter Regions, Genetic|Cell Line, Tumor|DNA|TET2 protein, human 122 SIM2 29427302 Cancer Sci. 2018 PMC5891185 10.1111/cas.13531 5 31 0 147 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Squamous Cell Carcinomas|Epithelial-Mesenchymal Transition|Transcription Factor|Basic Helix-Loop-Helix Transcription Factors|Transfections|Cell Line, Tumor|Gene Expression Regulation 122 SKA3 30506958 J. Cell. Biochem. 2018 10.1002/jcb.28228 11 1 0 193 Humans|*Computational Biology|Protein Interaction Maps|Gene Expression Profiling|Gene Ontology|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Software|*Brain|Algorithm|Brain Neoplasms|Transcription Factor|Ska3 protein, human|Microtubule-Associated Proteins 37 SKA3 30459531 Cancer Cell Int. 2018 PMC6236911 10.1186/s12935-018-0670-4 7 12 0 193 Humans|Female|*Uterine Cervical Neoplasms|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Cell Proliferation|*Signal Transduction|Cell Movement|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Transformation, Neoplastic|Ska3 protein, human|Microtubule-Associated Proteins 37 SKA3 30402980 Cancer Med 2018 PMC6308054 10.1002/cam4.1613 7 0 0 193 *RNA, Circular|*Medulloblastoma|mRNA|Downregulation|MicroRNAs|Upregulation|Cell Proliferation|RNA, Small Interfering|Cell Line, Tumor|Biomarkers|Cell Transformation, Neoplastic|Cerebellar Neoplasms|*Biological Processes 37 SKA3 30087422 Sci Rep 2018 PMC6081467 10.1038/s41598-018-30302-2 1 8 0 193 Animals|*Neurogenesis|Xenopus laevis|Xenopus Proteins|Neural Stem Cells|*Zinc Finger|Neurons|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Cell Differentiation|Transcription Factor|Brain|Gene Regulatory Networks|Aging|Cell Proliferation 37 SKA3 29928475 Oncotarget 2018 PMC6003567 10.18632/oncotarget.25410 7 2 0 193 miRNAs|Gene Expression Regulation, Neoplastic|Carcinoma, Renal Cell|Kidney Neoplasms|Cell Movement|Cell Line, Tumor|Cell Proliferation|Gene Expression Profiling|Oncogenes|Oncogenesis 37 SKA3 29487209 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC5856539 10.1073/pnas.1718553115 18 21 0 193 Humans|*Kinetochores|*Weight-Bearing|*Chromosome Segregation|Microtubules|Microtubule-Associated Proteins|Cytoskeletal Proteins|Nuclear Proteins|Protein Binding|Phosphorylation|NDC80 protein, human|Ska3 protein, human 37 SKA3 29359816 Bioessays 2018 PMC5885758 10.1002/bies.201700176 2 28 0 193 Humans|*Kinetochore|*Chromosome Segregation|Spindle Apparatus|Microtubules|Microtubule-Associated Proteins|NDC80 protein, human|Nuclear Proteins|CDC2 Protein Kinase|Cytoskeletal Proteins|Phosphorylation|Ska3 protein, human 37 SKOR1 30111810 Sci Rep 2018 PMC6093889 10.1038/s41598-018-30665-6 4 9 0 30 *Restless Legs Syndrome|*Genes, Homeobox|Genome-Wide Association Study|*Transcription Factor, Meis1|Transcription Factors|MAP Kinase Kinase 5|Homeodomain Proteins|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Neoplasm Proteins|Haplotype|Case-Control Studies 24 SLC16A12 29978464 Int. J. Cancer 2018 10.1002/ijc.31667 4 0 0 24 Humans|*Helicobacter pylori|*DNA Methylation|*B-DNA|*Gastric Mucosa|Helicobacter Infections|CpG Islands|Gastric Cancer|Promoter Regions, Genetic|Carcinogenesis|Cell Transformation, Neoplastic|Biopsies|Telomere|Genome|PRDM5 protein, human|DNA-Binding Proteins|Transcription Factors 24 SLC16A9 29997484 Front Behav Neurosci 2018 PMC6028559 10.3389/fnbeh.2018.00125 0 12 0 89 Child|Infant, Newborn|Female|Humans|Pregnancy|*DNA Methylation|*Prenatal Exposure Delayed Effects|ethyl glucuronide|Glucuronates|Meconium|Epigenesis, Genetic|Attention|Ethanol|Alcohol Drinking|P3 Event-Related Potential|Cognition|Cohort Studies|Biomarkers|*DNA 30 SLC16A9 29850377 Cureus 2018 PMC5973493 10.7759/cureus.2382 0 25 0 89 urate transporter|*Organic Anion Transporters|Hyperuricemia|Uric Acid|Glucose Transport Proteins, Facilitative|Genetic Susceptibility|*Metabolic Diseases|Mutations 30 SLC16A9 29658079 Bull. Exp. Biol. Med. 2018 10.1007/s10517-018-4074-1 2 2 0 89 Female|Pregnancy|Humans|*Human Umbilical Vein Endothelial Cells|RELB protein, human|*Transcription Factor RelB|NF-kappa B p52 Subunit|NF-kappa B|Transcription Factor RelA|I-kappa B Kinase|Signal Transduction|*Lymphotoxin-alpha|Cell Line, Tumor|NFKB2 protein, human 30 SLC16A9 29299135 Oncotarget 2018 PMC5746370 10.18632/oncotarget.22655 2 16 0 89 Humans|*Protein Kinase Inhibitors|*Phosphatidylinositol 3-Kinases|*Glycolysis|*DNA, Mitochondrial|ErbB Receptors|*Mutation|Lung Cancer|MTOR protein, human|*TOR Serine-Threonine Kinases|dactolisib|Quinolines|Phosphoinositide-3 Kinase Inhibitors|Imidazoles|PTEN protein, human|PTEN Phosphohydrolase|Drug Resistance, Neoplasm|Proto-Oncogene Proteins c-akt|Antineoplastic Agents 30 SLC22A9 30442650 Drug Metab. Dispos. 2018 10.1124/dmd.118.080549 0 0 0 139 Humans|lesinurad|*Uric Acid|*Thioglycolates|*Triazoles|Uricosuric Agents|Gout|Organic Cation Transport Proteins|Hyperuricemia|Organic Anion Transporters|*Biological Transport|Protein Binding|HEK293 Cells 30 SLC22A9 29906129 Mol. Pharm. 2018 10.1021/acs.molpharmaceut.8b00320 2 0 0 139 Humans|*Organic Anion Transport Proteins|Chromatography, Liquid|Tandem Mass Spectrometry|*Hepatocytes|*Liver|Organic Anion Transporters, Sodium-Independent|Biological Transport|HEK293 Cells|Membrane Transport Proteins 30 SLC22A9 29558500 PLoS ONE 2018 PMC5860731 10.1371/journal.pone.0194044 6 2 0 139 Humans|Adult|*Genome-Wide Association Study|Republic of Korea|Glomerular Filtration Rate|Single Nucleotide Polymorphisms|Genetic Loci|Creatinine|Chronic Kidney Disease|Kidney|Genetic Predisposition to Disease|*Phenotype|Uric Acid|Urea Nitrogen, Blood|Cohort Studies|ALDH2 protein, human|Aldehyde Dehydrogenase, Mitochondrial|SLC22A12 protein, human|Organic Anion Transporters|Organic Cation Transport Proteins 30 SLC22A9 29439128 Drug Metab. Dispos. 2018 10.1124/dmd.117.079285 5 0 0 139 Humans|*Proteomics|*Biological Transport|*Liver|Hepatocytes|Organic Anion Transporters, Sodium-Independent|Chromatography, Liquid|sodium-bile acid cotransporter|Organic Anion Transporters, Sodium-Dependent|Organic Anion Transporters|Membrane Transport Proteins|Tandem Mass Spectrometry|Symporters|HEK293 Cells|*Biochemical Phenomena 30 SLC25A24 30587500 Cancer Genomics Proteomics 2018 PMC6348402 10.21873/cgp.20112 0 0 0 148 Humans|*Poliovirus|*Genome, Human|Poliomyelitis|Poliovirus Vaccine, Oral|Genome, Viral|*Colorectal Cancer|*Colonic Neoplasms 27 SLC25A24 30374660 Hum. Genet. 2018 10.1007/s00439-018-1949-1 6 0 0 148 *Anophthalmos|*Microphthalmos|*Syndrome|Hedgehog Proteins|Pedigree|Mutation|Phenotype|Genetic Association Studies|Aldehyde Oxidoreductases 27 SLC25A24 30329211 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40496 4 0 0 148 Male|Humans|Adolescent|Progeroid Syndrome, Congenital, Petty Type|*Progeria|*Growth Disorders|Gorlin Chaudhry Moss syndrome|Craniofacial Abnormalities|Hypertrichosis|Abnormalities, Multiple|Ductus Arteriosus, Patent|Mitochondrial Proteins|Mitochondria|Antiporters|Mutation|Phenotype|Syndrome|Calcium-Binding Proteins|SLC25A24 protein, human 27 SLC25A24 29787394 Curr. Opin. Pediatr. 2018 PMC7241654 10.1097/MOP.0000000000000653 2 0 0 148 Humans|Genome-Wide Association Study|*Dwarfism|Growth Disorders|Exome|High-Throughput Nucleotide Sequencing|Mutation 27 SLC25A24 29785189 Evid Based Complement Alternat Med 2018 PMC5896210 10.1155/2018/3523126 0 12 0 148 Humans|Animals|Echinococcosis|Echinococcus granulosus|Albendazole|Sophora|Drug Therapy, Combination|Traditional Chinese Medicine|China 27 SLC25A24 29643985 Oncotarget 2018 PMC5884640 10.18632/oncotarget.24503 3 5 0 148 Humans|Male|Mice|Animals|*Prostate|*Mutagenesis, Insertional|*Prostate Cancer|*Oncogenes|Lentivirus|Genetic Vectors|*Disease Progression|*Neoplastic Processes|Androgens|Genes, Tumor Suppressor|Proto-Oncogenes|Base Sequence 27 SLC25A38 30214775 Clin Case Rep 2018 PMC6132150 10.1002/ccr3.1667 0 2 0 20 Infant|Humans|Female|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Genetic Diseases, X-Linked|*Hematopoietic Stem Cell Transplantation|Transplantation Conditioning|Mitochondrial Membrane Transport Proteins|Mutation|Slc25a38 protein, human 35 SLC25A38 30076742 J. Cell. Biochem. 2018 10.1002/jcb.27184 4 0 0 20 Humans|*Carcinoma, Hepatocellular|*Liver Cancer|*Prognosis|Neoplasm Recurrence, Local|Network, Gene|Gene Expression Profiles|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Computational Biology|Protein Interaction Maps|Disease Progression|Signal Transduction|Iron|FLVCR1 protein, human|Receptors, Virus|Membrane Transport Proteins|Slc25a38 protein, human 35 SLC25A38 29568862 Mol Med Rep 2018 PMC5928667 10.3892/mmr.2018.8759 0 18 0 20 Rats|Mice|Animals|Apoptosis|Mitochondria|Cell Survival|Reactive Oxygen Species|Insulin-Secreting Cells|Oxidative Stress|Protein, Mitochondrial|Signal Transduction|Cell Line, Tumor 35 SLC25A38 29499877 Blood Cells Mol. Dis. 2018 10.1016/j.bcmd.2018.02.002 2 0 0 20 Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Whole Exome Sequencing|Iran|*Genetic Diseases, X-Linked|Mitochondrial Membrane Transport Proteins|*Mitochondrial Gene|*Mitochondria|Mutations|Phenotypes|Mutations, Frame Shift|Missense Mutation|Slc25a38 protein, human 35 SLC4A11 30557570 Exp. Eye Res. 2018 PMC6389376 10.1016/j.exer.2018.12.003 2 0 0 80 Humans|Mice|Animals|Corneal dystrophy and perceptive deafness|*Corneal Dystrophies, Hereditary|Corneal endothelial dystrophy type 2|Anion Transport Proteins|Fuchs Endothelial Corneal Dystrophy|*Protein Transport|Antiporters|*Mutations|Hearing Loss, Sensorineural|*Iridocorneal Endothelial Syndrome|HEK293 Cells|Mutation, Missense|Cell Membrane|SLC4A11 protein, human|Slc4a11 protein, mouse|Symporters 104 SLC4A11 30267097 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24590 2 0 0 80 Humans|Russia|*Fuchs Corneal Dystrophy|Transcription Factor 4|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Trinucleotide Repeat Expansion|Genetic Predisposition to Disease|Alleles|Genotype|Polymorphism, Genetic|*Cohort Studies|Polymerase Chain Reaction|Transcription Factors|*Biomarkers|SLC4A11 protein, human|Antiporters|Anion Transport Proteins 104 SLC4A11 30140924 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24301 3 2 0 80 Humans|Endothelial Cells|*Corneal Dystrophies, Hereditary|Anion Transport Proteins|*Mutation|Antiporters|Fuchs Endothelial Corneal Dystrophy|SLC4A11 Protein|*Eyes|HEK293 Cells|Plasma Membrane|Protein Transport|*Anti-Inflammatory Agents, Non-Steroidal|SLC4A11 protein, human 104 SLC4A11 29924831 PLoS ONE 2018 PMC6010250 10.1371/journal.pone.0199178 3 0 0 80 Humans|*Keratoconus|Australia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Cohort Studies|Eye Proteins|Base Sequence|Homeodomain Proteins|*Continental Population Groups|SLC4A11 protein, human|Antiporters|Anion Transport Proteins 104 SLFN12 30379917 PLoS ONE 2018 PMC6209300 10.1371/journal.pone.0206511 5 1 0 86 Humans|Female|*Multiple Sclerosis|*DNA Methylation|*B-DNA|*CD8-Positive T-Lymphocytes|CpG Islands|CD4-Positive T-Lymphocytes|Multiple Sclerosis, Relapsing-Remitting|HLA DRB1|Epigenesis, Genetic|Phenotypes|Up-Regulation|Genome|Case-Control Studies|NINJ2 protein, human|Cell Adhesion Molecules, Neuronal 24 SLFN12 30045019 Cell. Physiol. Biochem. 2018 PMC6123821 10.1159/000492019 8 49 0 86 Humans|*Enterocytes|*Cell Differentiation|Cell Proliferation|Caco-2 Cells|Sucrase-Isomaltase Complex|Transfection|RNA, Messenger|Dipeptidyl Peptidase 4|SERPINB12 protein, human|Serpins 24 SMARCAD1 30308496 Cell. Physiol. Biochem. 2018 10.1159/000494163 1 0 0 367 Humans|Mice|Female|Animals|Neoplasm Invasiveness|*Disease Progression|Cell Line, Tumor|Cell Movement|Triple-Negative Breast Cancers|Xenograft Model Antitumor Assays|RNA Interference|Cell Proliferation|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|*Neoplastic Processes|Mice, Nude|DNA Helicases|SMARCAD1 protein, human 50 SMARCAD1 30289605 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40485 0 0 0 367 Humans|*Syndrome|Basan syndrome|*Dysplasia, Ectodermal|Fingerprints, Absence of|*Skin Diseases, Genetic|Nails, Malformed|*Skin|*Mutations|Donor Site, Splice|Pedigree|*Protein Isoforms|DNA Helicases|Hypohidrosis|SMARCAD1 protein, human 50 SMARCAD1 29899141 Genes Dev. 2018 PMC6049510 10.1101/gad.310995.117 9 0 0 367 *Nucleosomes|*ATPase|*Base Pairing|*Base Pair Mismatch|Saccharomyces cerevisiae Proteins|MutS Homolog 2 Protein|Mismatch Repair|Saccharomyces cerevisiae|DNA-Binding Proteins|MutL Protein Homolog 1|Protein Binding|Mutations 50 SMARCAD1 29888761 iScience 2018 PMC5993204 10.1016/j.isci.2018.03.016 8 46 0 367 *DNA Breaks, Double-Stranded|*Phosphorylation|*DNA Repair|*Ubiquitination|Homologous Recombination|Recombination Repair, Homologous|*DNA|DNA-Binding Proteins|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Nuclear Proteins|Histones|Tumor Suppressor Proteins|Transcription Factors|DNA Damage|Radiation, Ionizing 50 Smoc2 30594556 EBioMedicine 2018 PMC6412073 10.1016/j.ebiom.2018.12.044 7 45 0 125 Humans|Female|*Drug Resistance, Neoplasm|*Cancer Stem Cell|*Cell Proliferation|Cell Line, Tumor|Wnt Signaling Pathway|Cell Movement|Gene Expression Regulation, Neoplastic|*Endometrial Carcinoma|*Gene Targeting 70 Smoc2 30581002 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.12.006 0 4 0 125 Humans|Mice|Animals|*Diet, High-Fat|Osteonectin|Nonalcoholic Fatty Liver Disease|*Inflammation|Liver|Fibrosis, Liver|Insulin Resistance|Mice, Knockout|*Transforming Growth Factor|Mice, Inbred C57BL|CRIP1 protein, human|LIM Domain Proteins|Lipids 70 Smoc2 30518528 Genetics 2018 PMC6366928 10.1534/genetics.118.301805 2 1 0 125 Animals|Caenorhabditis elegans Proteins|Caenorhabditis elegans|Bone Morphogenetic Proteins|Transforming Growth Factor beta|Signal Transduction|Neuropeptides|Gene Expression Regulation, Developmental|Body Size|Homeostasis 70 Smoc2 30021376 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.03.058 0 8 0 125 Animals|Mice|*Bleomycin|Mice, Inbred C57BL|*Pulmonary Fibrosis|Smad3 Protein|Smad2 Protein|Lung|Transforming Growth Factor beta1|Collagen|Epithelial-Mesenchymal Transition|Collagen Type I|Signal Transduction|Cytokines 70 Smoc2 29969831 Oral Dis 2018 PMC6318069 10.1111/odi.12931 0 0 0 125 PAX9 Transcription Factor|AXIN2 protein, human|Axin Protein|WNT10A protein, human|Wnt Proteins|MSX1 Transcription Factor|Ectodysplasins|Anodontia|WNT10B protein, human|Genotype-Phenotype Correlation|Mutations|Genetic Predisposition to Disease|Phenotype 70 Smoc2 29914266 Br. Poult. Sci. 2018 10.1080/00071668.2018.1490495 0 0 0 125 Animals|Chick Embryo|*Mesenchymal Stem Cells|Chondrogenesis|Osteogenesis|Cell Differentiation|Lineages, Cell|Adipogenesis|Thy-1 Antigens|Cell Culture|Cell Proliferation|Stem Cells|CD44 protein, human|Hyaluronan Receptors|*Intestine|Cell Therapy|Flow Cytometry 70 Smoc2 29897942 PLoS ONE 2018 PMC5999237 10.1371/journal.pone.0198104 1 13 0 125 Humans|Osteogenesis|*Endothelial Cells|Calcification, Physiologic|Cell Differentiation|Osteoblasts|*Calcinosis|Calcium-Binding Proteins|Extracellular Matrix Proteins|Cells, Cultured|Cell Transdifferentiation|Extracellular Matrix|Alkaline Phosphatase 70 Smoc2 29879364 J. Dent. Res. 2018 10.1177/0022034518777460 2 0 0 125 Humans|PAX9 Transcription Factor|Hypodontia|*Mutations|AXIN2 protein, human|Axin Protein|WNT10A protein, human|Wnt Proteins|Ectodysplasins|MSX1 Transcription Factor|Phenotype|Genotypes 70 Smoc2 29769011 Recent Pat Anticancer Drug Discov 2018 10.2174/1574892813666180517102801 1 0 0 125 *T Cell Lymphoma|Histone Deacetylase Inhibitors|Lymphoma, T-Cell, Peripheral|Antineoplastic Agents|T-Lymphocytes|Gene Expression Regulation, Neoplastic|Signal Transduction|Antineoplastic Combined Chemotherapy Protocols 70 Smoc2 29575674 Oral Dis 2018 10.1111/odi.12861 2 0 0 125 *Dentin Dysplasia|Dentinogenesis Imperfecta|Sialoglycoproteins|Extracellular Matrix Proteins|Phosphoproteins|Phenotype|Mutations|Amino Acid Sequence|Tooth, Deciduous 70 Smoc2 29467240 Development 2018 PMC5897593 10.1242/dev.153049 14 0 0 125 Mice|Animals|Humans|*Adenoma|*Colonic Neoplasms|Colon|Organoids|Wnt Signaling Pathway|Colorectal Neoplasms|Intestine|Intestinal Mucosa|Neoplastic Stem Cells|Receptors, G-Protein-Coupled|Immunohistochemistry|Adenocarcinomas|LGR5 protein, human|Lgr5 protein, mouse 70 Smoc2 29374777 J. Gastroenterol. 2018 PMC6132922 10.1007/s00535-018-1437-3 9 0 0 125 Humans|*Organoids|*Crohn Disease|*Single-Cell Analysis|*Stem Cell|Intestine, Small|Intestines|Intestinal Mucosa|*Intestinal Diseases|Cell Proliferation 70 SMPDL3B 30386262 Front Psychiatry 2018 PMC6198178 10.3389/fpsyt.2018.00496 3 1 0 44 Humans|Male|Animals|Mice|*Sphingomyelin Phosphodiesterase|Depressive Disorder, Major|*Ceramides|*Liver|Mice, Inbred C57BL|Housing, Animal|Stress, Psychological 23 SMPDL3B 29343457 Matrix Biol. 2018 10.1016/j.matbio.2018.01.006 6 0 0 44 sphingosine 1-phosphate|Lysophospholipids|Sphingosine|sphingosine kinase|Phosphotransferases (Alcohol Group Acceptor)|Sphingolipids|Ceramides|*Signal Transduction|Sphingomyelin Phosphodiesterase|*Fibrosis|sphingosine 1-phosphate lyase (aldolase)|Aldehyde-Lyases|Glucosylceramides|Inflammation|haematoside synthetase|Sialyltransferases|ceramide glucosyltransferase|Glucosyltransferases 23 SNCG 30394624 Protein Sci. 2018 PMC6319761 10.1002/pro.3549 2 3 0 3567 epigallocatechin gallate|*Green Tea|*Catechin|Lewy Bodies|alpha-Synuclein|Parkinson Disease|*Polyphenols|Protein Aggregates|Kinetics|Calorimetry 169 SNCG 30394350 J Acupunct Meridian Stud 2018 10.1016/j.jams.2018.10.008 0 0 0 3567 Animals|Rabbits|*RNA-Seq|Alcian Blue|Meridians|Lymphatic Vessels|Acupuncture Points|Staining and Labeling|Coloring Agents|*Whole Exome Sequencing|Genes, MHC Class II|Abdomen 169 SNCG 30335075 Zh Nevrol Psikhiatr Im S S Korsakova 2018 10.17116/jnevro201811809168 0 0 0 3567 Humans|*gamma-Synuclein|*Autoantibodies|*Exon|Neoplasm Proteins|*Polymorphism, Genetic|*Genetic Code 169 SNCG 29937996 Oncotarget 2018 PMC6007952 10.18632/oncotarget.25415 3 14 0 3567 *gamma-Synuclein|Neoplasm Proteins|Disease-Free Survival|Biomarkers, Tumor|Cell Line, Tumor|siRNA 169 SNCG 29903032 J. Exp. Clin. Cancer Res. 2018 PMC6003176 10.1186/s13046-018-0783-6 2 39 0 3567 Humans|*gamma-Synuclein|*Focal Adhesion Protein-Tyrosine Kinases|PTK2 protein, human|*Focal Adhesion Kinase 1|*Signal Transduction|*Integrins|*Cell Motility|Integrin beta1|Cell Adhesion|Phosphorylation|Cell Line, Tumor|Matrix Metalloproteinases 169 SNCG 29902801 Cytogenet. Genome Res. 2018 10.1159/000488571 2 5 0 3567 Animals|Mice|*RNA, Small Interfering|*Stomach Neoplasms|*Proto-Oncogene Proteins c-akt|*Phosphorylation|Mice, Nude|*Synuclein|*Mice, Inbred BALB C|*Downregulation|RNA Silencing|Cell Proliferation|Cell Line, Tumor|Transfections|Cell Movement|Gene Expression Regulation, Neoplastic|Apoptosis|Xenograft Model Antitumor Assays|*RNA, Double-Stranded 169 SNCG 29853639 J. Biol. Chem. 2018 PMC6052208 10.1074/jbc.RA118.002780 15 1 0 3567 *Membrane Fluidity|alpha-Synuclein|*Lecithins|Lipid Bilayers|Protein Conformation|Parkinson Disease|*Acetylation|Circular Dichroism 169 SNCG 29851342 Biochemistry 2018 10.1021/acs.biochem.8b00343 2 10 0 3567 Humans|Lewy Bodies|beta-Synuclein|alpha-Synuclein|gamma-Synuclein|Parkinson Disease|Protein Aggregates|Protein Conformation|Brain|Homology, Sequence 169 SNCG 29795373 Cell Death Dis 2018 PMC5967338 10.1038/s41419-018-0657-z 5 55 0 3567 *gamma-Synuclein|TWIST1 protein, human|*Twist-Related Protein 1|*Nuclear Proteins|*Cell Movement|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Promoter Regions, Genetic|Transforming Growth Factor beta|*Transforming Growth Factor|Cell Line, Tumor|Signal Transduction|Cell Proliferation|Upregulation|Transcriptional Activation 169 SNCG 29745080 J BUON 2018 0 0 0 3567 gamma-Synuclein|*Tomography, Spiral Computed|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|RNA, Messenger 169 SNX10 30487700 World J. Gastroenterol. 2018 PMC6250920 10.3748/wjg.v24.i43.4906 2 0 0 57 *Prognosis|*Sorting Nexins|*Stomach Neoplasms|*Adenocarcinoma|Biomarkers, Tumor|Gene Expression Profiling|Neoplasm Staging|Gene Expression Regulation, Neoplastic|Stomach 51 SNX10 29867114 Cell Death Dis 2018 PMC5986761 10.1038/s41419-018-0719-2 5 23 0 57 Humans|Male|Mice|Animals|*Sorting Nexins|Caco-2 Cells|MTOR protein, human|*Mammalian Target of Rapamycin|*Colorectal Cancer|HCT 116 Cells|Signal Transduction|Tumorigenesis|Cell Proliferation|*Colonic Neoplasms|SNX10 protein, mouse 51 SNX10 29452206 J. Hepatol. 2018 10.1016/j.jhep.2018.01.038 6 6 0 57 Mice|Animals|*Chaperone-Mediated Autophagy|*Chemical and Drug Induced Liver Injury, Chronic|*Fatty Liver|*Liver|Alcoholic Liver Disease|*Ethanol|Hepatocytes|Mice, Knockout|Lipid Metabolism|Oxidative Stress|Lysosomes|SNX10 protein, mouse|Sorting Nexins 51 SNX10 29355659 Cancer Lett. 2018 10.1016/j.canlet.2018.01.045 8 1 0 57 Mice|Animals|*Sorting Nexins|*Chaperone-Mediated Autophagy|*Tumorigenesis|*Colorectal Cancer|*Cell Transformation, Neoplastic|*Genes, Tumor Suppressor|Cyclin-Dependent Kinase Inhibitor p21|*Disease Progression|*Colonic Neoplasms|Cell Proliferation|Cell Line, Tumor|Signal Transduction|SNX10 protein, mouse 51 SNX27 30559172 J. Cell Biol. 2018 PMC6363445 10.1083/jcb.201806153 0 0 0 396 Humans|*Protein Transport|Endosomes|IGF2R protein, human|Receptor, IGF Type 2|Sorting Nexins|trans-Golgi Network|Lysosome|Golgi complex autoantigen, 97-kDa|Golgi Matrix Proteins|Vesicular Transport Proteins|Carrier Proteins|HeLa Cells|Protein Binding|Autophagy|Autoantigens|SNX3 protein, human 97 SORCS2 30387693 Neuroscientist 2018 10.1177/1073858418810142 4 0 0 141 BDNF protein, human|*Brain-Derived Neurotrophic Factor|Receptor, trkB|Receptors, Nerve Growth Factor|Nerve Tissue Proteins|Hippocampus|Neurons|Adaptor Proteins, Vesicular Transport|Brain|Signal Transduction|Posttranslational Modifications|Genetic Variation 54 SORCS2 30252935 Alcohol. Clin. Exp. Res. 2018 PMC6317871 10.1111/acer.13890 2 0 0 141 *Substance Withdrawal Syndrome|*Alcoholism|Polymorphism, Single Nucleotide 54 SORCS2 30061605 Nat Commun 2018 PMC6065357 10.1038/s41467-018-05405-z 2 30 0 141 NGF protein, human|*Nerve Growth Factor|Receptors, Nerve Growth Factor|Brain-Derived Neurotrophic Factor|Nerve Tissue Proteins|Ligands|Signal Transduction|Protein Precursors|Binding Sites|Amino Acid Sequence|Neuronal Plasticity|Carrier Proteins 54 SORCS2 29938835 Neuropathology 2018 10.1111/neup.12484 1 0 0 141 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Lewy Bodies|*Hyalin|*Inclusion Bodies|Anterior Horn Cells|Motor Neurons|Spinal Cord|*DNA Binding Protein|Cu-Superoxide Dismutase|CST3 protein, human|Cystatin C|Mutations|Transferrin|TDP-43 protein, human 54 SORCS2 29914355 BMC Genomics 2018 PMC6006668 10.1186/s12864-018-4710-1 1 5 0 141 Animals|Humans|*Neanderthals|Hominidae|Genome, Human|Fossils 54 SORCS2 29909994 Neuron 2018 PMC6054457 10.1016/j.neuron.2018.05.024 12 2 0 141 Humans|*Brain-Derived Neurotrophic Factor|*Dendritic Spines|*Fear|Extinction, Psychological|Conditioning, Classical|Synapses|Hippocampus|Neurons|Prefrontal Cortex|Polymorphism, Single Nucleotide 54 SORCS2 29868584 Front Cell Dev Biol 2018 PMC5962823 10.3389/fcell.2018.00054 0 2 0 141 Humans|*Clustered Regularly Interspaced Short Palindromic Repeats|red fluorescent protein|*Protein A|Luminescent Proteins|Gene Editing|RNA, Guide|CRISPR-Cas Systems|Endonucleases|Gene Knockout Techniques|Transfections|INDEL Mutation|Bacterial Proteins 54 SORCS2 29405286 J. Comp. Neurol. 2018 10.1002/cne.24403 2 0 0 141 Animals|Mice|sortilin|SORL1 protein, human|*LDL-Receptor Related Proteins|Adaptor Proteins, Vesicular Transport|*Membrane Transport Proteins|Neurons|Receptors, Cell Surface|Nerve Tissue Proteins|Axon Guidance|Gene Expression Regulation, Developmental|Spinal Cord|Plate, Cortical|Hippocampus|Mesencephalon|SorCS2 protein, mouse 54 SORCS2 29315502 Clin. Pharmacol. Ther. 2018 PMC6037621 10.1002/cpt.1014 0 0 0 141 Humans|Female|*Atazanavir Sulfate|*Genome-Wide Association Study|HIV Protease Inhibitors|Ritonavir|Viral Load|HIV-1|HIV Infections|Drug Monitoring|*Hair|Cohort Studies 54 SOSTDC1 30367460 Br. J. Dermatol. 2018 10.1111/bjd.17352 1 1 0 169 *Scleroderma, Localized|*Fibroblasts|Myofibroblasts|Transforming Growth Factor beta1|Smad2 Protein|Cell Differentiation|Cells, Cultured|Wound Healing|Signal Transduction|Cell Proliferation 122 SOSTDC1 30325689 J. Dent. Res. 2018 10.1177/0022034518803095 0 2 0 169 Mice|Animals|Bone Morphogenetic Proteins|Hedgehog Proteins|Wnt Proteins|Tooth Germs|Signal Transduction|Teeth|Bone Morphogenetic Protein 4|Gene Expression Regulation, Developmental|Molars|In Situ Hybridization|Shh protein, mouse 122 SOSTDC1 30320379 Int. J. Mol. Med. 2018 PMC6202094 10.3892/ijmm.2018.3926 1 3 0 169 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Bone Neoplasms|Neoplasm Invasiveness|Downregulation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Lung|SOSTDC1 protein, human|Proteins 122 SOSTDC1 30261159 Life Sci. 2018 10.1016/j.lfs.2018.09.042 0 0 0 169 *Ureter|*Transcriptome|*Urinary Tract|*Kidney|Mutation 122 SOX21 30382873 BMC Med Genomics 2018 PMC6211550 10.1186/s12920-018-0407-1 9 0 0 81 Glioblastoma Multiforme|*Prognosis|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Kaplan-Meier Estimate|Biomarkers, Tumor|Glioma 77 SOX21 30143969 Mol. Neurobiol. 2018 10.1007/s12035-018-1299-y 9 9 0 81 Mice|Animals|*RNA, Long Noncoding|*Wnt Signaling Pathway|*Alzheimer Disease|*Upregulation|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Oxidative Stress|Cell Movement|MicroRNAs|*Neurons|Cell Line, Tumor|*Transcriptional Activation|Prognosis|Apoptosis|Fzd3 protein, mouse|Frizzled Receptors 77 SOX21 30103323 J. Alzheimers Dis. 2018 10.3233/JAD-180277 1 0 0 81 Humans|Female|Mice|Male|Animals|*Alzheimer Disease|*Transcription Factors|*Neurogenesis|*Hippocampus|Presenilin-1|Amyloid beta-Protein Precursor|Mice, Transgenic|*Disease Models, Animal|Amyloid beta-Peptides|Dentate Gyrus|Neural Stem Cells|Neurons|Memory Loss|Amyloid|Cell Differentiation|Microtubule-Associated Proteins|Cognition Disorders 77 SOX21 30038703 Oncotarget 2018 PMC6049862 10.18632/oncotarget.25434 5 12 0 81 *Glioblastoma|*RNA, Long Noncoding|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|RNA, Messenger 77 SOX21 29867344 Front Mol Neurosci 2018 PMC5952183 10.3389/fnmol.2018.00152 2 27 0 81 *GABAergic Neurons|*Mesencephalon|SOXB2 Transcription Factors|Transcription Factors|High Mobility Group Proteins|Cell Differentiation|Neurogenesis|Gene Expression Regulation, Developmental|SOXB1 Transcription Factors|Neural Stem Cells 77 sp110 30465816 Biochim Biophys Acta Gen Subj 2018 10.1016/j.bbagen.2018.11.011 0 2 0 198 Humans|*PHD Zinc Fingers|*Sumoylation|*SUMO-1 Protein|SP140 protein, human|*Antigens, Nuclear|*Transcription Factors|*Protein Domains|Cell Nucleus|Transcription, Genetic|Gene Expression Regulation|Post-Translational Modifications|Binding Sites|Protein Binding|Phosphorylation|Autoantigens|Amino Acid Sequence|Sp110 protein, human|Nuclear Proteins 84 sp110 30353169 Mol. Psychiatry 2018 PMC6478563 10.1038/s41380-018-0282-3 3 0 0 198 Humans|United States|*Suicide|Utah|*Suicide, Completed|Suicide, Attempted|Genome-Wide Association Study|Genotypes|Families, Extended|Violence|*Multiple Births|Risk Factors|Sp110 protein, human|Nuclear Proteins|Minor Histocompatibility Antigens 84 sp110 29920932 Am. J. Transplant. 2018 10.1111/ajt.14971 1 1 0 198 Humans|*Transplant Recipients|Cohort Studies|*Diabetes Mellitus|Single Nucleotide Polymorphisms|Organ Transplantation|Kidney Transplantation|Genetic Predisposition to Disease|Immunosuppressive Agents|Risk Factors|*Biomarkers 84 sp110 29642903 J. Biomed. Sci. 2018 PMC5894228 10.1186/s12929-018-0434-4 3 18 0 198 *Gene Expression Regulation|Nuclear Protein|SP140 protein, human|Antigens, Nuclear|Transcription Factors|Mycobacterium tuberculosis Infection|Cell Nucleus|NF-kappa B|Transcription, Genetic|Transcriptional Activation|Minor Histocompatibility Antigens|Cell Line|Immunity, Innate|Amino Acid Sequence|Protein Isoforms 84 sp110 29552658 Heliyon 2018 PMC5852290 10.1016/j.heliyon.2018.e00535 3 1 0 198 Cattle|Animals|*Paratuberculosis|Mycobacterium avium subsp. paratuberculosis|Cattle Diseases|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Markers|Case-Control Studies 84 sp110 29430075 Dis. Markers 2018 PMC5752994 10.1155/2017/4590235 5 5 0 198 Humans|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Asian Continental Ancestry Group|Genotype|Tuberculosis, Pulmonary|Minor Histocompatibility Antigens|Odds Ratio|Case-Control Studies|Tumor Necrosis Factor-alpha|Nuclear Proteins 84 SPAG16 30481930 Zhonghua Zhong Liu Za Zhi 2018 10.3760/cma.j.issn.0253-3766.2018.11.003 0 7 0 28 28 SPAG16 30300419 PLoS ONE 2018 PMC6177184 10.1371/journal.pone.0205422 4 1 0 28 Humans|Axonemal Dyneins|Kartagener Syndrome|Heterozygote|Mutation|Exome|Cilia|High-Throughput Nucleotide Sequencing|Genetic Testing|Homozygote|*Genetic Profile|Genomics|Cohort Studies 28 SPAG6 30535028 J Mol Cell Biol 2018 10.1093/jmcb/mjy014 8 1 0 61 59 SPAG6 30149579 Int J Mol Sci 2018 PMC6163198 10.3390/ijms19092512 3 0 0 61 59 SPAG6 29778923 Theriogenology 2018 10.1016/j.theriogenology.2018.04.025 1 0 0 61 59 SPAG6 29749435 Int. J. Oncol. 2018 10.3892/ijo.2018.4390 3 9 0 61 59 SPAG6 29726644 Zhonghua Nan Ke Xue 2018 0 0 0 61 59 SPANXA1 29717166 Sci Rep 2018 PMC5931513 10.1038/s41598-018-25032-4 2 1 0 37 Humans|Male|Sperm Motility|*Proteomics|Prospective Studies|*Artificial Insemination|Semen Analysis|Sperm|Infertility, Male|Semen|Sperm Count|Fertility|*Proteins 27 SPANXA1 29453317 Mol. Cancer Res. 2018 10.1158/1541-7786.MCR-17-0460 2 3 0 37 Male|Humans|Child|histone H3 trimethyl Lys4|*Histones|*Testis|*Glioma|Brain Neoplasms|Polycomb Repressive Complex 2|DNA Methylation|Lysine|Mutations|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Chromatin Immunoprecipitation|Methionine 27 SPATA16 30584989 Andrologia 2018 10.1111/and.13221 1 0 0 7 Humans|Male|Female|*Teratozoospermia|Infertility, Male|Intracytoplasmic Sperm Injection|Acrosome|Spermatozoa|Point Mutation|Gene Deletion|Membrane Proteins|Exons|Heterozygote|DPY19L2 protein, human 33 SPATA16 30358834 Hum. Reprod. 2018 10.1093/humrep/dey319 8 0 0 7 Humans|Male|*Infertility, Male|CpG Islands|Sperm|Spermatogenesis|DNA Methylation|Fertility 33 SPATA16 32212452 Zhonghua Nan Ke Xue 2018 0 0 0 7 Humans|Male|*Teratozoospermia|Infertility, Male|Sperm Head|Aurora Kinase C|Spermatozoa|Membrane Proteins|Mutation|SUN5 protein, human|Proteins|DPY19L2 protein, human|DNAH1 protein, human|Dyneins|SPATA6 protein, human|Cytoskeletal Proteins 33 SPATA16 30108436 Saudi J Biol Sci 2018 PMC6088112 10.1016/j.sjbs.2017.12.005 3 0 0 7 Female|Humans|*Infertility|Steroidogenic Factor 1|Gonadal Dysgenesis, 46,XY|Primary Ovarian Insufficiency|Phenotype|Pedigree|Mutation 33 SPEF2 30594591 Gen. Comp. Endocrinol. 2018 10.1016/j.ygcen.2018.12.011 0 1 0 21 Animals|*Receptors, Prolactin|*Chickens|*Feathers|Phenotype|RNA, Messenger|Amino Acid Sequence 34 SPEF2 30190587 Sci Rep 2018 PMC6127338 10.1038/s41598-018-31743-5 4 5 0 21 Animals|Mice|*Cilia|*Mice, Inbred C57BL|Ependyma|*Brain|Hydrocephalus|*Disease Models, Animal|Primary Ciliary Dyskinesia|Cerebral Ventricles|Proteins|*Gene Expression|Phenotype|*Biochemical Processes|SPEF2 protein, mouse 34 SPEF2 29924355 Poult. Sci. 2018 10.3382/ps/pey231 0 0 0 21 Female|Male|Animals|*Chickens|*Feathers|Avian Leukosis Virus|*Phenotype|RFLP|Genotype|PCR|Genes, Viral|Homozygote 34 SPEF2 29801437 BMC Genomics 2018 PMC5970437 10.1186/s12864-018-4773-z 1 7 0 21 Animals|*Feathers|*RNA, Micro|*Chickens|Gene Expression Profiling|*Skin|Receptors, Prolactin|Gene Expression Regulation, Developmental|Phenotypes|RNA, Messenger 34 SPEF2 29339787 Sci Rep 2018 PMC5770417 10.1038/s41598-018-19204-5 6 9 0 21 Mice|Male|Animals|*Osteogenesis|*Cilia|*Cell Differentiation|Osteoblasts|Bone|Chondrocytes|Core Binding Factor Alpha 1 Subunit|Bone Mineral Content|Femur|Tibia|Cartilage|Mice, Knockout|Bone Growth|Cells, Cultured|X-Ray Microtomography|SPEF2 protein, mouse|Proteins 34 spic 30360471 Molecules 2018 PMC6278506 10.3390/molecules23112729 1 0 0 154 *Cynara scolymus|*Polyphenols|*Endothelial Cell|Antioxidants|Plant Extracts|*Skin Aging 143 SPOCK2 29708036 Eur J Prev Cardiol 2018 10.1177/2047487318759120 1 5 0 42 *Aortic Aneurysm, Thoracic|*Focal Adhesions|*Extracellular Matrix|Aneurysm, Dissecting|PXN protein, human|Paxillin|PTK2 protein, human|Focal Adhesion Kinase 1|mRNA|*Cell Adhesion|Downregulation|Focal Adhesion Kinase 35 SPOCK2 29414802 Cell. Physiol. Biochem. 2018 10.1159/000487166 2 1 0 42 *Carcinoma, Hepatocellular|*B virus, Hepatitis|*Proteomics|*Liver Neoplasms|Hepatitis B Virus Infection|Hep G2 Cells|Virus Replication|RNA Interference|RNA, Small Interfering|Cell Line, Tumor 35 srpx 30008265 Mol. Cancer 2018 PMC6047127 10.1186/s12943-018-0846-5 7 9 0 33 Humans|Female|*Exosomes|*Transcriptome|Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Forkhead Box Protein M1|Biomarkers, Tumor|Cell Line, Tumor|Up-Regulation|Cell Proliferation 50 srpx 29920554 PLoS ONE 2018 PMC6007900 10.1371/journal.pone.0199399 1 6 0 33 Humans|Mice|Animals|*Synapse|SRPUL protein, human|*Membrane Proteins|Vesicular Glutamate Transport Protein 1|Nerve Tissue Proteins|*Neoplasm Proteins|Neurons|Cerebral Cortex|*Language|*Genes, Regulator|Neurogenesis|SRPX2 protein, human 50 srpx 29663392 J. Comp. Neurol. 2018 10.1002/cne.24449 0 0 0 33 Humans|Rats|Mice|Animals|Supraoptic Nucleus|AVP protein, human|Vasopressin|Hypothalamus|*Hypophysis|Neurophysins|Oxytocin|Paraventricular Hypothalamic Nucleus|*Pituitary Diseases|Protein Precursors|Hypothalamo-Hypophyseal System|Neurons|Neurohypophysis|In Situ Hybridization|SRPUL protein, human|Membrane Proteins|Neoplasm Proteins|Immunohistochemistry 50 srpx2 30551519 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.10.042 0 6 0 105 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Cell Proliferation|Cisplatin|Carcinoma, Squamous Cell|Cell Line, Tumor|SRPUL protein, human|*Neoplasm Proteins|Epithelial-Mesenchymal Transition|Wnt Signaling Pathway|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Movement|*Membrane Proteins|Gene Knockdown Techniques|Apoptosis|RNA, Small Interfering 75 srpx2 30537353 J. Biochem. Mol. Toxicol. 2018 10.1002/jbt.22237 0 6 0 105 Humans|Male|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|*Prostate Cancer|SRPUL protein, human|*Neoplasm Proteins|*Prostate|*Membrane Proteins|Cell Movement|Cell Line, Tumor|Epithelial-Mesenchymal Transition|Cell Proliferation|Nerve Tissue Proteins|SRPX2 protein, human 75 srpx2 30393191 Gene 2018 10.1016/j.gene.2018.10.067 0 1 0 105 Humans|Mice|Animals|SRPUL protein, human|*Membrane Proteins|*Neoplasm Proteins|Nerve Tissue Proteins|Language Disorder|Cerebral Cortex|Epilepsy|Neurons|Language|*Genes, Regulator|Apraxias|Intellectual Disability|Speech|Forkhead Transcription Factors|Phenotype|SRPX2 protein, human 75 srpx2 30251989 Zh Nevrol Psikhiatr Im S S Korsakova 2018 10.17116/jnevro2018118081118 0 0 0 105 Humans|Child|*Speech|Landau-Kleffner Syndrome|Epilepsy, Rolandic|Electroencephalography|Aphasia|Status Epilepticus|Sleep|*Language|Language Disorders|*Neurodevelopmental Disorders|Mutations 75 srpx2 29976148 BMC Genet. 2018 PMC6034250 10.1186/s12863-018-0628-5 0 1 0 105 *Sleep, Slow-Wave|DNA Copy Number Variations|*Status Epilepticus|Sleep|Epilepsy|Electroencephalography|Syndromes|Mutations 75 srpx2 29920554 PLoS ONE 2018 PMC6007900 10.1371/journal.pone.0199399 0 6 0 105 Humans|Mice|Animals|*Synapse|SRPUL protein, human|*Membrane Proteins|Vesicular Glutamate Transport Protein 1|Nerve Tissue Proteins|*Neoplasm Proteins|Neurons|Cerebral Cortex|*Language|*Genes, Regulator|Neurogenesis|SRPX2 protein, human 75 srpx2 29881288 Onco Targets Ther 2018 PMC5983007 10.2147/OTT.S158820 0 12 0 105 Humans|Male|*Prostate Cancer|Prostate|SRPUL protein, human|*Neoplasm Proteins|Prognosis|*Membrane Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Kaplan-Meier Estimate|Nerve Tissue Proteins|RNA, Messenger|Real-Time Polymerase Chain Reaction|SRPX2 protein, human 75 srpx2 29663392 J. Comp. Neurol. 2018 10.1002/cne.24449 0 0 0 105 Humans|Rats|Mice|Animals|Supraoptic Nucleus|AVP protein, human|Vasopressin|Hypothalamus|*Hypophysis|Neurophysins|Oxytocin|Paraventricular Hypothalamic Nucleus|*Pituitary Diseases|Protein Precursors|Hypothalamo-Hypophyseal System|Neurons|Neurohypophysis|In Situ Hybridization|SRPUL protein, human|Membrane Proteins|Neoplasm Proteins|Immunohistochemistry 75 STEAP4 30337524 Nat Commun 2018 PMC6194020 10.1038/s41467-018-06817-7 0 0 0 257 Humans|*Iron|*Cryoelectron Microscopy|Flavin-Adenine Dinucleotide|NADP|Oxidoreductases|Heme|Kinetics|Oxidation-Reduction|Binding Sites|Amino Acid Sequence|STEAP4 protein, human|Membrane Proteins 89 STEAP4 29940176 Exp. Cell Res. 2018 10.1016/j.yexcr.2018.06.022 0 0 0 257 Male|*Protein Transport|*Cell Movement|*Cholesterol|Plasma Membrane|Endosome|Endocytosis|Neoplasm Proteins|Membrane Proteins|*Membrane|Biological Transport 89 STEAP4 29569248 Electrophoresis 2018 10.1002/elps.201700467 0 0 0 257 lipopolysaccharide B|*Lipopolysaccharides|*Proteomics|*Liver|Inflammation|Oxidative Stress|Liver Diseases|Proteomes|Weaning|Signal Transduction 89 STEAP4 29475580 Am. J. Obstet. Gynecol. 2018 PMC6070341 10.1016/j.ajog.2018.01.009 1 0 0 257 Pregnancy|Humans|Female|Adult|Animals|Infant, Newborn|*Gene Regulatory Networks|*Fetus|*Prenatal Care|Chorioamnionitis|Interleukin 6|Inflammation|Cytokines|Fetal Diseases|Interleukin-1beta|Streptococcal Infections|Macaca nemestrina|RNA, Messenger|*Heart 89 STK17B 29445189 Cell Death Dis 2018 PMC5833726 10.1038/s41419-018-0262-1 7 35 0 215 Humans|*Carcinoma, Hepatocellular|*Glycogen Synthase Kinase 3|*Proto-Oncogene Proteins c-akt|*Liver Neoplasms|*Signal Pathway|*Carcinogenesis|Snail Family Transcription Factors|Epithelial-Mesenchymal Transition|Phosphatidylinositol 3-Kinases|Gene Expression Regulation, Neoplastic|Cell Movement|Upregulation|MicroRNAs|*Neoplastic Processes|Cell Line, Tumor|Cell Proliferation|Xenograft Model Antitumor Assays 32 STK33 30555514 Front Genet 2018 PMC6282001 10.3389/fgene.2018.00589 4 0 0 144 48 STK33 30453067 Gene 2018 10.1016/j.gene.2018.11.042 5 0 0 144 Adolescent|Female|Humans|*Menarche|Russia|Haplotypes|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Age Factors|*Adolescent Development 48 STK33 30256516 J. Cell. Mol. Med. 2018 PMC6201369 10.1111/jcmm.13792 1 27 0 144 Mice|Animals|*Gentamycin|*Ototoxicity|*Hair Cells, Cochlear|*Organ of Corti|CASP3 protein, human|Caspase 3|Mitochondria|Reactive Oxygen Species|Apoptosis|Cochlea|Cisplatin|Protein Synthesis Inhibitors|Cell Survival|Aminoglycosides|*Nuclear Receptor Subfamily 1, Group D, Member 1|Anti-Bacterial Agents|*Protein-Serine-Threonine Kinases 48 STK33 30149579 Int J Mol Sci 2018 PMC6163198 10.3390/ijms19092512 3 0 0 144 Humans|Female|Neoplasm Recurrence, Local|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Fallopian Tube|Fallopian Tube Neoplasms|Epithelial Ovarian Cancer|Epithelium|Cell Transformation, Neoplastic 48 STK33 29894909 Eur. J. Cancer 2018 10.1016/j.ejca.2018.05.001 10 2 0 144 Humans|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Proto-Oncogene Proteins p21(ras)|Mutation|Antineoplastic Agents|Biomarkers, Tumor|Prognosis|KRAS protein, human 48 STK33 29764119 Cancer Res Treat 2018 PMC6333986 10.4143/crt.2018.157 0 0 0 144 Humans|*Whole Exome Sequencing|Poland|*Incidence|*Melanoma|Exome|Mutations, Germline|Genetic Predisposition to Disease|Pedigree|Mutation 48 STK33 29434919 Oncol Lett 2018 PMC5776884 10.3892/ol.2017.7614 5 4 0 144 Humans|*Colorectal Cancer|DNA Methylation|Prognosis|*Protein-Serine-Threonine Kinases|Biomarkers, Tumor|Cell Line, Tumor|Cell Proliferation|*Colonic Neoplasms|Lymphatic Metastasis|Tumorigenesis|mRNA|Gene Expression|Serine 48 STK33 29367428 Clin. Cancer Res. 2018 PMC6765216 10.1158/1078-0432.CCR-17-3346 8 4 0 144 48 STK40 30237828 Mob DNA 2018 PMC6139936 10.1186/s13100-018-0135-2 2 0 0 141 Animals|Humans|*Phylogeny|*Primates|*RNA Splicing|Retroelements|Alu Elements|Evolution, Molecular|*Men|Transcription, Genetic 24 STK40 29854300 Oncotarget 2018 PMC5978250 10.18632/oncotarget.25187 3 32 0 141 Humans|Neoplasm Recurrence, Local|*Triple-Negative Breast Cancers|Low Density Lipoprotein Receptor-Related Protein-6|Low Density Lipoprotein Receptor-Related Protein-5|Wnt Pathway|beta Catenin|LRP5 protein, human|STK40 protein, human|Protein-Serine-Threonine Kinases 24 STYX 30472486 Eur J Med Genet 2018 10.1016/j.ejmg.2018.11.016 0 0 0 164 Child|Humans|*Mutation, Missense|Intellectual Disability|Sequencing, Whole Exome|Homozygote|Exome|Developmental Disabilities|Epilepsy|Pedigree|Mutations|Genetic Association Studies|Siblings|Problem Behavior 64 STYX 30141112 Wien Med Wochenschr 2018 PMC6132567 10.1007/s10354-018-0652-0 0 0 0 164 Humans|Necrosis|Autophagy|Apoptosis|Cell Death|Phagocytosis|Homeostasis|STYX protein, human|Nuclear Proteins|Intracellular Signaling Peptides and Proteins 64 STYX 30077638 Biochim Biophys Acta Mol Cell Res 2018 10.1016/j.bbamcr.2018.07.021 3 0 0 164 Male|*Signal Transduction|Protein Tyrosine Phosphatase|Intracellular Signaling Peptides and Proteins|Charcot-Marie-Tooth Disease|Cell Differentiation|Neurite 64 STYX 29303256 Environ. Sci. Technol. 2018 10.1021/acs.est.7b05250 0 0 0 164 Nitrous Oxide|Atmosphere|Ice 64 SULF2 30562637 Neoplasia 2018 PMC6297269 10.1016/j.neo.2018.11.010 0 4 0 302 Humans|*Irinotecan|CpG Islands|Promoter Regions, Genetic|Colorectal Cancer|DNA Methylation|*Treatment Outcome|Poly-ADP-Ribose Binding Proteins|Neoplasm Proteins|Cell Cycle Proteins|*Colonic Neoplasms|Antineoplastic Combined Chemotherapy Protocols|*Rectal Neoplasms|Ubiquitin-Protein Ligases|CHFR protein, human 169 SULF2 30535007 Cereb. Cortex 2018 PMC6319179 10.1093/cercor/bhy286 3 0 0 302 Animals|Humans|*Gyrus Cinguli|*Transcriptome|*Microdissections|*Neurons|Cerebral Cortex|Brain|Hominidae|Pyramidal Neurons|*Sequencing, RNA|*Base Sequence|*Whole Exome Sequencing|Cell Count 169 SULF2 30470661 Cytokine 2018 10.1016/j.cyto.2018.11.007 0 10 0 302 Rats|Animals|*Rats, Inbred SHR|*Endothelin-1|*Muscle, Smooth, Vascular|*Angiotensin II|*Myocytes, Smooth Muscle|Rats, Inbred WKY|CXCL8 protein, human|*Interleukin-8|Hypertension|RNA, Small Interfering|Cell Signaling|Receptor, Angiotensin II Type 1|*Sulfatases|Blood Pressure|RNA Interference|Up-Regulation|Chemokine CCL5|Downregulation 169 SVOP 29938834 Clin Exp Optom 2018 10.1111/cxo.12803 0 0 0 115 Child|Humans|Animals|Perimetry|Visual Field|*Saccades|Vision Disorders|*Vision, Low|Cognitive Dysfunction|*Disease Vectors|Histological Techniques 26 SVOP 29880917 Eye (Lond) 2018 PMC6169726 10.1038/s41433-018-0135-y 0 0 0 115 Child|Animals|Humans|Child, Preschool|*Visual Field Tests|*Visual Fields|*Vision Disorders|*Saccades|*Brain Neoplasms|Technology|*Disease Vectors 26 SVOP 29332093 Ophthalmic Res. 2018 10.1159/000480296 0 0 0 115 Adult|Child|Humans|Child, Preschool|*Perimetry|Visual Field|*Vision Disorders|*Saccades|Optic Nerve Diseases|Hemianopsia|Retinal Ganglion Cells|Nerve Fibers|Coherence Tomography, Optical|Visual Acuity|*Blindness 26 SWAP70 30190566 Sci Rep 2018 PMC6127261 10.1038/s41598-018-31802-x 2 0 0 162 Swine|Animals|*Breeding|*Genome|*Genomics|*Phenotypes|Natural Selection|Genotype|Polymorphism, Single Nucleotide|Meat 81 SWAP70 30049706 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6099861 10.1073/pnas.1808585115 5 48 0 162 Phytophthora infestans|Plant Immunity|Solanum tuberosum|Plant Diseases|Tobacco|Plant Proteins|Plants, Genetically Modified|Host-Pathogen Interactions|Cell Death|Ubiquitin-Protein Ligases 81 SWAP70 29483597 Nat. Immunol. 2018 PMC6095139 10.1038/s41590-018-0056-8 16 34 0 162 Humans|Mice|Animals|*Autoimmunity|interferon regulatory factor-4|*Interferon Regulatory Factors|IRF5 protein, human|*B Cells|Lupus Erythematosus, Systemic|Brachyury protein|T-Box Domain Proteins|DNA-Binding Proteins|Nuclear Proteins|Guanine Nucleotide Exchange Factors|Minor Histocompatibility Antigens|Mice, Knockout|interleukin-21|Interleukins|Fetal Proteins|Irf5 protein, mouse 81 synpo 30546987 Beilstein J Nanotechnol 2018 PMC6278773 10.3762/bjnano.9.269 1 0 0 489 phenylphosphonic acid|Bisphenol A-Glycidyl Methacrylate|*Organophosphorus Compounds|Composite Resins|Surface Properties|Materials Testing|Silanes|*Calcium, Dietary|Stress, Mechanical|Microscopy, Electron, Scanning|Polymers|*Minerals 231 synpo 30464326 Sci Rep 2018 PMC6249220 10.1038/s41598-018-35465-6 1 1 0 489 Humans|Mice|Animals|*Podocytes|*Intermediate Filaments|SYNPO protein, human|*Microfilament Proteins|Kidney Glomerulus|Focal Segmental Glomerulosclerosis|Kidney|Proteinuria|Kidney Diseases|Adriamycin|Membranous Nephropathy|VCL protein, human|Vinculin|*Protective Agents|Upregulation|Peptides 231 synpo 30448842 Cell. Physiol. Biochem. 2018 10.1159/000495205 5 6 0 489 *Podocytes|*Chronic Kidney Disease|Guanylate Kinases|Adaptor Proteins, Signal Transducing|Intracellular Signaling Peptides and Proteins|Membrane Proteins|*Genes, Regulator|Gene Expression Profiling|Proteinuria 231 synpo 30361092 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.10.081 1 4 0 489 Humans|Mice|Animals|*Podocytes|*Septins|Diabetic Nephropathy|*Apoptosis|Hyperglycemia|Glucose|Diabetes Mellitus, Experimental|Down-Regulation|Up-Regulation|Signal Transduction 231 synpo 30230988 J. Neurophysiol. 2018 10.1152/jn.00447.2018 2 0 0 489 Rats|Animals|*Calcium|*Neurons|*Hippocampus|Action Potentials|Small-Conductance Calcium-Activated Potassium Channels|Membrane Potentials|*Calcium, Dietary|Calcium Channel Blockers 231 synpo 30177952 Front Genet 2018 PMC6109778 10.3389/fgene.2018.00330 1 2 0 489 Sheep|Animals|*Rumen|*Methane|*Transcriptome|Ruminants|*Phenotypes|*Cell Junction|*Muscle|*Muscle Cell|*Lipids 231 synpo 30139698 Nefrologia 2018 10.1016/j.nefro.2018.05.009 1 0 0 489 Child|Humans|*Fabry Disease|alpha-Galactosidase|Podocytes|Albuminuria|Case-Control Studies 231 TARBP1 29731880 Oncol Lett 2018 PMC5920659 10.3892/ol.2018.8202 3 0 0 41 Humans|*Carcinoma, Non-Small-Cell Lung|*Prognosis|*Lung Neoplasms|Immunohistochemistry|Biomarkers, Tumor|Proportional Hazards Models|Kaplan-Meier Estimate|Lung|mRNA|Cell Line, Tumor|Real-Time Polymerase Chain Reaction|Up-Regulation|Survival Rate|TARBP1 protein, human|Nuclear Proteins|RNA-Binding Proteins 26 TBPL1 30236477 Biochem. Pharmacol. 2018 10.1016/j.bcp.2018.09.014 2 7 0 1191 VEGFA protein, human|*Vascular Endothelial Growth Factor A|KDR protein, human|*VEGFR-2|Neuropilin-1|Neovascularization, Physiologic|Protein Binding|Endothelial Cells|Binding Sites|Signal Transduction|Cell Movement|Endothelium, Vascular|Cells, Cultured 28 TBPL1 29351916 Clin. Cancer Res. 2018 10.1158/1078-0432.CCR-17-0252 9 0 0 1191 28 TBX20 30536204 J Cardiovasc Transl Res 2018 10.1007/s12265-018-9851-8 2 1 0 264 Humans|*Cardiomyopathy, Dilated|Homeobox Protein Nkx-2.5|Transcription Factors|GATA4 Transcription Factor|Heterozygote|Homeodomain Proteins|T-Box Domain Proteins|Pedigree|Mutation, Missense|Mutation|Genetic Predisposition to Disease|Base Sequence|Case-Control Studies|TBX20 protein, human 167 TBX20 30512176 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2018 10.3760/cma.j.issn.1003-9406.2018.06.032 0 0 0 264 Gene Regulatory Networks|*Cardiac Valves|Cell Proliferation|T-Box Domain Proteins|Cell Differentiation|Organogenesis|Gene Expression Regulation, Developmental|Epithelial-Mesenchymal Transition|Signal Transduction 167 TBX20 30427827 PLoS Genet. 2018 PMC6261631 10.1371/journal.pgen.1007754 4 0 0 264 Animals|Mice|*Zebrafish|*Mutagenesis|Zebrafish Proteins|CRISPR-Cas Systems|Gene Knock-In Techniques|CRISPR|Genome|*Oligonucleotides|tbx20 protein, zebrafish|T-Box Domain Proteins 167 TBX22 30462376 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40630 1 0 0 28 Humans|*Sequencing, Whole Exome|Cleft palate X-linked|Cleft Palate|Cleft Lip|Genetic Diseases, X-Linked|X-Linked Inheritance|CHARGE Syndrome|Mutations|T-Box Domain Proteins|Phenotype|Pedigree|Ankyloglossia|Hypodontia|Transcription Factors|Palate|Choanal Atresia 52 TBX22 29932061 J. Genet. 2018 0 0 0 28 52 TBX22 29704302 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.38690 0 0 0 28 Humans|Male|Mice|Animals|*Ankyloglossia|Cleft palate X-linked|Cleft Palate|*Mouth Abnormalities|*Tooth Abnormalities|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Lingual Frenum|Genetic Diseases, X-Linked|X-Linked Gene|Pedigree|Mutations|Tongue Diseases|Phenotype|T-Box Domain Proteins 52 tbxt 30237576 Genet. Med. 2018 PMC6752307 10.1038/s41436-018-0138-x 13 0 0 369 Exome|Genetic Testing|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|Phenotypes|Genomics|Homozygote|Mutation|Genetic Variation 75 tbxt 30061699 Sci Rep 2018 PMC6065435 10.1038/s41598-018-29740-9 2 56 0 369 Animals|*Xenopus laevis|Xenopus Proteins|*Nervous System|Homeodomain Proteins|T-Box Domain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Repressor Proteins|Cell Differentiation|Neurogenesis|Signal Transduction|Promoter Regions, Genetic 75 TCF15 29301788 Arterioscler. Thromb. Vasc. Biol. 2018 10.1161/ATVBAHA.117.310549 6 0 0 58 *Transcriptome|Endothelial Cells|*Heart|*B Cells|Cells, Cultured|Promoter Regions, Genetic|Capillaries|Cell Differentiation 39 TDRD3 30456381 Life Sci Alliance 2018 PMC6238599 10.26508/lsa.201800117 7 4 0 132 coactivator-associated arginine methyltransferase 1|PRMT2 protein, human|*Protein-Arginine N-Methyltransferases|*Transcription Factors|Methylation|Histones|Arginine|Protein Binding|Lysine|Intracellular Signaling Peptides and Proteins|RNA 25 TDRD3 29954329 BMC Genomics 2018 PMC6022433 10.1186/s12864-018-4882-8 2 1 0 132 Animals|*Beak|*Genome-Wide Association Study|*Chickens|Phenotype|Polymorphism, Single Nucleotide|Breeding|Gene Expression Regulation|Beijing 25 TDRD3 29645362 FEBS J. 2018 10.1111/febs.14469 1 0 0 132 *Tudor Domain|Amino Acid Sequence|Protein Binding|Crystallography, X-Ray|Hydrogen Bond|FMR1 protein, human|Fragile X Mental Retardation Protein|Models, Molecular|Histone|Arginine 25 TDRD3 29501774 Biochim Biophys Acta Mol Basis Dis 2018 10.1016/j.bbadis.2018.02.021 4 4 0 132 Humans|*Protein-Arginine N-Methyltransferases|*Enolase|*Lung Adenocarcinoma|*Cell Movement|*Cell Membrane|*Protein Transport|Tumor Suppressor Proteins|Biomarkers, Tumor|Lung Neoplasms|DNA-Binding Proteins|Cell Line, Tumor 25 TDRD3 29471495 Nucleic Acids Res. 2018 PMC5888246 10.1093/nar/gky103 7 35 0 132 Animals|*Methylation|*Arginine|Protein Arginine Methyltransferase|*Protein Processing, Post-Translational|Cytoplasmic Granules|Repressor Proteins|Lysine|RNA|DNA 25 TEN1 30082315 J. 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Chem. 2018 PMC6139565 10.1074/jbc.RA118.004598 4 5 0 78 Mice|Animals|*Replication Protein A|*Telomere|Ctc1 protein, human|*Telomere-Binding Proteins|*Signal Transduction|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|DNA, Single-Stranded|Aminopeptidases|Serine Proteases|DNA Damage|*Transcription Factors|Protein Binding|*Chromosome Structures|POT1b protein, mouse|DNA-Binding Proteins 122 TEN1 30067734 PLoS Genet. 2018 PMC6089452 10.1371/journal.pgen.1007523 3 31 0 78 Humans|*Saccharomyces cerevisiae|*Telomere|*Open Reading Frames|Telomere-Binding Proteins|Saccharomyces cerevisiae Proteins|Telomerase|Chromosomal Proteins, Non-Histone|Cell Cycle Proteins|*Yeast, Dried|Decay, Nonsense-Mediated mRNA|Protein Binding|DNA Damage|Ten1 protein, human|Stn1 protein, human|TEN1 protein, S cerevisiae 122 TEN1 30026550 Nat Commun 2018 PMC6053418 10.1038/s41467-018-05154-z 10 32 0 78 Humans|*Telomere|*Telomerase|Telomere-Binding Proteins|Telomere Homeostasis|Telomere Shortening|DNA Replication|DNA Polymerase I|*Colon|*Colon Cancer|Ten1 protein, human|Ctc1 protein, human|Stn1 protein, human 122 TEN1 30022158 Nature 2018 PMC6072559 10.1038/s41586-018-0324-7 54 7 0 78 *DNA Breaks, Double-Stranded|TP53BP1 protein, human|*Tumor Suppressor p53-Binding Protein 1|DNA End-Joining Repair|DNA Repair|Telomere-Binding Proteins|BRCA1 Protein|Recombinational DNA Repair|Mad2 Proteins|Poly(ADP-ribose) Polymerase Inhibitors|Cell Line, Tumor 122 TEN1 29774655 Aging Cell 2018 PMC6052479 10.1111/acel.12783 7 4 0 78 Humans|*Telomere|Telomere Length Maintenance|Telomere-Binding Proteins|Telomerase|DNA Polymerase I|DNA Replication|Mutations|Protein Binding|HEK293 Cells|Ten1 protein, human|Ctc1 protein, human|Stn1 protein, human 122 TEN1 29774234 Sci Adv 2018 PMC5955624 10.1126/sciadv.aar2740 3 50 0 78 *Schizosaccharomyces|*Telomere|*Telomerase|Telomere-Binding Proteins|Telomere Homeostasis|Schizosaccharomyces pombe Proteins|DNA Replication|Sumoylation|Protein Binding|Stn1 protein, S pombe|Tpz1 protein, S pombe|Carrier Proteins 122 TENM3 30273960 J. Orthop. Res. 2018 10.1002/jor.24148 3 1 0 39 Humans|Infant, Newborn|Mice|Animals|*Hip Dislocation, Congenital|Acetabulum|Pedigree|Exome|Mutation|Polymorphism, Single Nucleotide|Phenotype|DNA|Base Sequence|CX3C Chemokine Receptor 1 28 TENM3 29753094 Eur J Med Genet 2018 10.1016/j.ejmg.2018.05.004 1 0 0 39 Child|Humans|Microphthalmia and mental deficiency|*Intellectual Disability|*Eye Abnormalities|Microphthalmia|Microcephaly|Coloboma|*Phenotypes|Brain Diseases, Metabolic, Inborn|Anophthalmia|Corneal Opacity|Homozygote|Heterozygote|Exome|Mutation|Nerve Tissue Proteins|Whole Exome Sequencing|Membrane Proteins|Eye 28 TENM3 29414938 Nature 2018 PMC7282895 10.1038/nature25463 26 1 0 39 Animals|Mice|*Hippocampus|Neurons|Axons|Entorhinal Cortex|Synapses|Nerve Tissue Proteins|Membrane Proteins|Tenascin|Protein Isoforms 28 TENM3 29351612 Ann. Oncol. 2018 PMC5913594 10.1093/annonc/mdy011 6 0 0 39 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Prognosis|*Mutations|Carcinoma, Squamous Cell|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|*Alcohol Consumption 28 TESC 30594602 Exp. Mol. Pathol. 2018 10.1016/j.yexmp.2018.12.004 2 1 0 122 Humans|*Carcinoma, Renal Cell|*NF kB|Cancer, Kidney|*Signal Transduction|*Downregulation|Cell Proliferation|Gene Expression Regulation, Neoplastic|Proto-Oncogene Proteins c-akt|*Neoplastic Processes|Cell Line, Tumor|RNA, Small Interfering 66 TESC 30287853 Sci Rep 2018 PMC6172220 10.1038/s41598-018-33096-5 0 17 0 122 Humans|*Sodium|*Protons|*Calcineurin|Sodium-Hydrogen Exchangers|Calmodulin|Sodium-Hydrogen Exchanger 1|Protein Binding|Calcium-Binding Proteins|Binding Sites|Amino Acid Sequence|Cation Transport Proteins|Hydrogen-Ion Concentration|*Ions|Transfection 66 TESC 30013043 Sci Rep 2018 PMC6048049 10.1038/s41598-018-29142-x 9 74 0 122 Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|IGF1R protein, human|*Receptors, Somatomedin|Cancer Stem Cell|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|Epithelial-Mesenchymal Transition|Radiation Tolerance|Cell Line, Tumor|src-Family Kinases|Signal Transduction|Gene Expression Regulation, Neoplastic|*Aldehyde Dehydrogenase 1|Insulin-Like Growth Factor I, Resistance To|*Growth Disorders|*Abnormalities, Multiple|Phosphorylation 66 TESC 29801633 J. Therm. Biol. 2018 10.1016/j.jtherbio.2018.04.002 4 0 0 122 Animals|*Brachyura|*Temperature|Acclimation|*Locomotor Activity|Habitat|*Drug Tolerance 66 TESC 29378913 J. Immunol. 2018 10.4049/jimmunol.1601689 1 17 0 122 Humans|*Th17 Cells|*RNA, Long Noncoding|MTOR protein, human|*TOR Serine-Threonine Kinases|*Cell Differentiation|T-Lymphocytes, Regulatory|CD4-Positive T-Lymphocytes|mRNA|Cytokines|Multiple Sclerosis|Leukocytes, Mononuclear|DDIT4 protein, human|Transcription Factors 66 TEX14 30289875 Med. Sci. Monit. 2018 PMC6186152 10.12659/MSM.910916 4 3 0 73 Humans|*Computational Biology|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|Protein Interaction Maps|Gene Ontology|Gene Regulatory Networks|*Leukemia, Myeloid, Acute|Gene Expression Profiling|Databases, Genetic|*Mutations|Protein Interaction Mapping|Transcriptome|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Prognosis|Clustering|Signal Transduction|OTOA protein, human 43 TEX14 29980567 Development 2018 PMC6110146 10.1242/dev.161323 3 0 0 73 Male|Mice|Animals|*Spermatogonia|Spermatids|Spermatocytes|Spermatogenesis|Testis|Meiosis|Cell Differentiation|*Mammals|*Cytoplasm|*Cytosol 43 TEX14 29932616 JBRA Assist Reprod 2018 PMC6106636 10.5935/1518-0557.20180030 3 0 0 73 Humans|Male|Spermatogenesis|Azoospermia|Infertility, Male|Testis|Meiosis|Chromosomal Proteins, Non-Histone|Cell Cycle Proteins|Fertility|Chromosomes|TEX15 protein, human 43 TEX14 29790874 Genet. Med. 2018 10.1038/gim.2018.10 6 0 0 73 Humans|Male|*Whole Exome Sequencing|*Point-of-Care Systems|Azoospermia, Nonobstructive|Azoospermia|*Infertility, Male|Homozygote|Spermatogenesis|Gene Frequency|Genetic Predisposition to Disease|Pedigree|Phenotype|Mutation|Middle East 43 TEX14 29683733 FASEB J. 2018 10.1096/fj.201701096RR 8 3 0 73 Humans|Male|Mice|Animals|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|Spermatogenesis|Spermatogonia|Testes|*Male Sterility|*Cell Cycle Proteins|*Signal Transduction|Spermatids|Cell Differentiation|Stem Cells|Cytokinesis|*Cell Nucleus|FOXO1 protein, human|Forkhead Box Protein O1|Cep55 protein, human|Nuclear Proteins|Foxo1 protein, mouse 43 TEX19 29907896 Chromosoma 2018 PMC6208735 10.1007/s00412-018-0674-9 4 3 0 48 Male|Mice|Animals|*Meiotic Prophase I|Synapsis|Spermatocytes|Meiosis|Pachytene Stage|DNA Breaks, Double-Stranded|Cell Cycle Proteins|Chromatin|DNA Repair|Endodeoxyribonucleases|Nuclear Proteins|Chromosome Segregation|Histones|*Homologous Recombination|Tex19 protein, mouse 20 Tfcp2l1 30241344 Int J Mol Sci 2018 PMC6213935 10.3390/ijms19102852 0 7 0 100 Female|Pregnancy|Humans|*Transcription Factors|DNA-Binding Proteins|Repressor Proteins|Promoter Regions, Genetic|Protein Binding|Cancer|TFCP2 protein, human 46 Tfcp2l1 30220521 Cell Stem Cell 2018 10.1016/j.stem.2018.08.016 18 0 0 100 Cellular Reprogramming|*Cell Differentiation|DNA Methylation|Induced Pluripotent Stem Cells|DNA-Binding Proteins|Chromatin|Transcription Factors|Embryonic Stem Cells|Cytosine|Proto-Oncogene Proteins|Fibroblasts|Promoter Regions, Genetic|*Regulatory Sequences, Nucleic Acid|Demethylation 46 Tfcp2l1 29572894 Anim. Genet. 2018 10.1111/age.12640 3 0 0 100 Pregnancy|Swine|Female|Animals|*Genome-Wide Association Study|*Gene Regulatory Networks|*Phenotype|Quantitative Trait Loci|Genotype|SNPs|Litter Size|Sus scrofa|Genetic Association Studies|Reproduction|myogenic factor 6|Myogenic Regulatory Factors 46 Tfcp2l1 29560096 Oncotarget 2018 PMC5849160 10.18632/oncotarget.23117 0 0 0 100 Humans|Male|Adolescent|Young Adult|Adult|Middle Aged|Testicular Germ Cell Tumor|*Testicular Neoplasms|Genome-Wide Association Study|*Risk Factors|*Neoplasms, Germ Cell and Embryonal|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|*Chromosome Structures 46 Tfcp2l1 29513567 Am. J. Physiol., Cell Physiol. 2018 10.1152/ajpcell.00292.2017 1 5 0 100 Mice|Animals|*Mouse Embryonic Stem Cells|*Stem Cell Self-Renewal|*Noncoding RNA|Wnt Signaling Pathway|Cell Differentiation|beta Catenin|Embryonic Stem Cells|T Cell Factor 3|Pluripotent Stem Cells|RNA, Long Noncoding|Transcription, Genetic|*Telomeres|Cell Line 46 Tfcp2l1 29410248 Cancer Lett. 2018 10.1016/j.canlet.2018.01.078 5 10 0 100 Transcription Factors|DNA-Binding Proteins|Repressor Proteins|Carcinogenesis|Embryonic Stem Cells|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Hepatocellular Carcinoma|3'-(1-butylphosphoryl)adenosine|*Complement Factor B|Liver Neoplasms 46 Tfcp2l1 29323720 J. Cell. Physiol. 2018 10.1002/jcp.26483 3 5 0 100 Humans|Mice|Animals|*Human Embryonic Stem Cells|*Stem Cell Self-Renewal|Mouse Embryonic Stem Cell|Cell Differentiation|Wnt Signaling Pathway|beta Catenin|Mesoderm|Repressor Proteins|Transcription Factor|Gene Expression Regulation 46 TFEC 30324847 Autophagy 2018 PMC6526814 10.1080/15548627.2018.1531198 7 17 0 72 *mTORC1|*Cadmium|*Mesenchymal Stem Cells|*Proto-Oncogene Proteins c-akt|*Autophagy|Lysosomes|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Calcineurin|Signal Transduction|Cell Nucleus|Phosphorylation|Protein Transport|AMP-Activated Protein Kinase|*Bone 93 TFEC 30286071 PLoS Genet. 2018 PMC6191144 10.1371/journal.pgen.1007402 4 1 0 72 Animals|*Neural Crest|*Gene Regulatory Networks|*Systems Biology|Zebrafish|Zebrafish Proteins|SOXE Transcription Factors|Chromatophores|Melanocytes|Gene Expression Regulation, Developmental|Microphthalmia-Associated Transcription Factor|Forkhead Transcription Factors|Ltk protein, zebrafish|Protein-Tyrosine Kinases 93 TFEC 29764979 EMBO J. 2018 PMC5983138 10.15252/embj.201798804 46 2 0 72 *Phosphorylation|Glycogen Synthase Kinase 3|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Lysosomes|MTOR protein, human|TOR Serine-Threonine Kinases|Autophagy|*Gene Expression Regulation|Mechanistic Target of Rapamycin Complex 1|Microphthalmia-Associated Transcription Factor|Cell Nucleus|Signal Transduction|Calcineurin|Homeostasis 93 TFEC 29303964 Cancers (Basel) 2018 PMC5789362 10.3390/cancers10010012 0 11 0 72 *Epstein-Barr Virus Nuclear Antigens|*Burkitt Lymphoma|Epstein Barr Virus|Cell Transformation, Viral|Viral Proteins|B-Lymphocytes|Viral Matrix Proteins|Gene Expression Regulation, Viral|Antigens, Viral|Transfection|*Lymphocytes|*Mass Spectrometry|Immunoprecipitation|Western Blotting|Protein Phosphatase 2A 93 TFPI2 30591460 Anticancer Res. 2018 10.21873/anticanres.13099 2 1 0 737 *Glioblastoma|Neoplasm Recurrence, Local|Brain Neoplasms|Temozolomide|Xenograft Model Antitumor Assays|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Survival|Antineoplastic Combined Chemotherapy Protocols|Apoptosis|Signal Transduction 125 TFPI2 30553473 Cancer Genet 2018 10.1016/j.cancergen.2018.05.003 1 0 0 737 Humans|*DNA Methylation|*Colorectal Cancer|*Colonic Neoplasms|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling 125 TFPI2 30423385 Gene 2018 10.1016/j.gene.2018.10.046 1 0 0 737 Humans|Male|Animals|*Prostate|*Phylogeny|Bayes Theorem|WFDC1 protein, human|*Proteins|*Evolution, Molecular|Prostate Cancer|Exons|Syntenic Conservation|Vertebrate 125 TFPI2 30233644 Front Genet 2018 PMC6133993 10.3389/fgene.2018.00356 2 0 0 737 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Tumor Suppressor Genes|DNA Methylation|Carcinoma, Squamous Cell|CpG Islands|Promoter Regions, Genetic|Epigenesis, Genetic|Tumor Suppressor Proteins|Biomarkers, Tumor|Cancer Early Diagnosis 125 TICRR 30037903 J. Biol. Chem. 2018 PMC6139568 10.1074/jbc.RA118.004519 0 6 0 110 Humans|*Chromatin|DNA Replication|Cell Cycle Proteins|Replication Origin|DNA-Binding Proteins|Nuclear Proteins|Carrier Proteins|Saccharomyces cerevisiae Proteins|DNA Helicases|Protein Binding|CDC45 protein, human 29 TICRR 29483155 Genes Dev. 2018 PMC5859964 10.1101/gad.306464.117 12 3 0 110 Nuclear Proteins|Transcription Factors|*DNA Replication|Cell Cycle Proteins|Chromatin|S Phase|Protein-Serine-Threonine Kinases|Replication Origin|Protein Binding|Epigenesis, Genetic 29 TIMD4 30538339 Nat. Immunol. 2018 PMC6565365 10.1038/s41590-018-0272-2 49 2 0 299 Mice|Animals|*Macrophages|*Myocardial Infarction|*Heart|Monocytes|Receptors, CCR2|Myocardium|CX3C Chemokine Receptor 1|Mice, Inbred C57BL|Antigens, Ly|Disease Models, Animal 81 TIMD4 30118845 Cancer Lett. 2018 10.1016/j.canlet.2018.08.012 14 5 0 299 Humans|Mice|Animals|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|Vascular Endothelial Growth Factor A|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|*Colorectal Cancer|HCT116 Cells|*Colonic Neoplasms|*Neovascularization, Pathologic|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|HT29 Cells|*Macrophages|Cell Survival|Upregulation 81 TIMD4 29979724 PLoS ONE 2018 PMC6034850 10.1371/journal.pone.0200081 1 1 0 299 Swine|Cattle|Animals|Sheep|*Foot-and-Mouth Disease Virus|Foot-and-Mouth Disease|Transcriptome Analysis|Gene Ontology|Gene Annotation|Sequence Analysis, RNA|Illumina Sequencing|Transcriptome|*Blood Cells|RNA|Cell Line|Real-Time Polymerase Chain Reaction 81 TIMD4 29920237 Biochim Biophys Acta Biomembr 2018 PMC6290684 10.1016/j.bbamem.2018.06.010 1 1 0 299 *Phosphatidylserines|Receptors, Virus|phosphatidylserine receptor|Receptors, Cell Surface|Membrane Glycoproteins|Hepatitis A Virus Cellular Receptor 1|Membrane Proteins|Hepatitis A Virus Cellular Receptor 2|*Membrane|Apoptosis 81 TIPARP 30373764 Biochem. J. 2018 PMC6292455 10.1042/BCJ20180347 5 0 0 455 PARP2 protein, human|*Poly(ADP-ribose) Polymerases|2,3,7,8-tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase, human|Receptors, Aryl Hydrocarbon|Polychlorinated Dibenzodioxins|Signal Transduction|Adenosine Diphosphate Ribose 59 TIPARP 30097864 Methods Mol. Biol. 2018 10.1007/978-1-4939-8588-3_8 2 0 0 455 2,3,7,8-tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase, human|*Poly(ADP-ribose) Polymerases|Mono-ADP-Ribosylation|Mono-ADP-Ribosyltransferase|Adenosine Diphosphate Ribose|Receptors, Aryl Hydrocarbon|Polychlorinated Dibenzodioxins|*Pentosyltransferases|NAD|Protein Processing, Post-Translational|Gene Expression Regulation 59 TIPARP 29938598 Autophagy 2018 PMC6103660 10.1080/15548627.2018.1458173 30 1 0 455 Humans|Animals|Mice|*Stroke|*Brain Ischemia|*RNA, Circular|*Astrocytes|*Autophagy|Middle Cerebral Artery Occlusion|*Nervous System Diseases|Neurons|MicroRNAs|Apoptosis|2,3,7,8-tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase, human|Poly(ADP-ribose) Polymerases|Up-Regulation|Mice, Inbred C57BL|*Neurogenesis|Cerebral Cortex|HectD1 protein, human|Ubiquitin-Protein Ligases 59 TIPARP 29873790 Toxicol. Sci. 2018 PMC6154274 10.1093/toxsci/kfy136 6 1 0 455 Mice|Animals|AHR protein, human|*Receptors, Aryl Hydrocarbon|*Dioxins|*Tetrachlorodibenzo-p-dioxin|*Basic Helix-Loop-Helix Transcription Factors|2,3,7,8-tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase, human|Poly(ADP-ribose) Polymerases|*Hepatocyte|*Cachexia|Steatohepatitis|*Wasting Syndrome|Mice, Knockout|Signal Transduction|Cell Line, Tumor|Parp7 protein, mouse|ADP Ribose Transferases 59 TIPARP 29738842 Toxicology 2018 10.1016/j.tox.2018.05.004 1 0 0 455 Female|Rats|Humans|Mice|Animals|*Dioxins|*Rodent|2,3,3',4,4'-pentachlorobiphenyl|Polychlorinated Biphenyls|2,3',4,4',5-pentachlorobiphenyl|3,4,5,3',4'-pentachlorobiphenyl|Polychlorinated Dibenzo-p-dioxins|Benzofurans|CYP1A1 protein, human|CYP1A1|Carcinogens|CYP1B1 protein, human|Cytochrome P-450 CYP1B1|Rats, Sprague-Dawley|*Lung 59 TIPARP 29311254 Hypertension 2018 PMC5877117 10.1161/HYPERTENSIONAHA.117.10527 1 7 0 455 Male|Female|*Blood Pressure|*Transcriptome|*Blood Pressure Determination|Hypertension|Genome-Wide Association Study|Transcriptome Analysis|Phenotype|Genotype|Cohort Studies|Finland 59 TIPARP 29302888 J. Neurooncol. 2018 10.1007/s11060-017-2730-3 4 1 0 455 Humans|AHR protein, human|*Receptors, Aryl Hydrocarbon|*Meningioma|*Basic Helix-Loop-Helix Transcription Factors|Aryl Hydrocarbon Receptor Nuclear Translocator|CYP1A1 protein, human|CYP1A1|*Signal Transduction|Transcriptional Activation|Up-Regulation|Cell Line, Tumor|Apoptosis|Cell Nucleus|Protein Binding|Meningeal Neoplasms 59 tiprl 30087317 Transl Psychiatry 2018 PMC6081446 10.1038/s41398-018-0211-x 2 0 0 1859 Humans|*Genome-Wide Association Study|*Asian|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Bipolar Disorder|Haplotypes|Depressive Disorder, Major|Case-Control Studies|Genotype 34 tiprl 30039834 Arch Ital Biol 2018 10.12871/00039829201814 0 0 0 1859 Rats|Animals|Conditioning, Psychological|Freezing Reaction, Cataleptic|Fear|*Gene Expression|Memory|Electroshock|Long-Term Memory|Hippocampus|*Phobic Disorders 34 tiprl 29348850 Oncotarget 2018 PMC5762535 10.18632/oncotarget.22614 2 33 0 1859 *Carcinoma, Hepatocellular|*Liver Neoplasms|*TNF-Related Apoptosis-Inducing Ligand|Mitogen-Activated Protein Kinase Kinase 7|c-jun N-Terminal Kinase|Apoptosis|*Indazoles|Cell Line, Tumor|Drug Resistance, Neoplasm|Mitogen-Activated Protein Kinase 8|*Corticosterone 34 TLE6 29606347 Reprod. Biomed. Online 2018 10.1016/j.rbmo.2018.03.009 6 0 0 17 Pregnancy|Female|Humans|Embryonic Development|Intracytoplasmic Sperm Injection|Blastocysts|Oocytes|Infertility, Female|Mutation|Phenotype|*Embryo, Mammalian|Sequencing, Whole Exome|Tle6 protein, human|Transcription Factors 23 TM4SF1 30537927 BMC Genomics 2018 PMC6288855 10.1186/s12864-018-5193-9 5 0 0 214 Humans|*Transcriptome|*Colorectal Cancer|*Transcriptome Profiling|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|*Genetic Marker|*Colonic Neoplasms|Cohort Studies 102 TM4SF1 30344751 Oncol Lett 2018 PMC6176369 10.3892/ol.2018.9411 0 6 0 214 Humans|*Stomach Neoplasms|TM4SF1 protein, human|*Neoplasm Proteins|*Apoptosis|*Antigens, Surface|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs 102 TM4SF1 30301667 Mol. Ther. 2018 PMC6277537 10.1016/j.ymthe.2018.09.006 6 1 0 214 Humans|*Nonsmall Cell Lung Cancer|Lung Neoplasms|Neoplasm Recurrence, Local|*Cell Transformation, Neoplastic|RNA, Micro|*Oncogene|Gene Expression Regulation, Neoplastic|*Tumorigenesis|Tumor Initiating Cells|Cell Line, Tumor|RNA Interference|Cell Proliferation|Downregulation|Apoptosis|Biomarkers, Tumor|Signal Transduction|3' Untranslated Regions|Cell Movement 102 TM4SF1 30277602 Glia 2018 PMC6240381 10.1002/glia.23467 8 5 0 214 Mice|Animals|Humans|*Astrocytes|*Chemotaxis|PROKR2 protein, human|Receptors, G-Protein-Coupled|Gastrointestinal Hormones|Receptors, Peptide|Neuropeptides|Signal Transduction|NFE2L2 protein, human|NF-E2-Related Factor 2|Mice, Inbred C57BL|Central Nervous System|Upregulation|Inflammation|Dopaminergic Neurons|Glutamate|Brain|TM4SF1 protein, human 102 TM4SF5 30584324 Onco Targets Ther 2018 PMC6284540 10.2147/OTT.S186606 3 5 0 210 Mice|Humans|Animals|*Liposomes|Hepatocellular Carcinoma|Liver Neoplasms|*Disease Models, Animal|peptide B|*Pancreatic Cancer|*Peptides|Cell Line, Tumor|Xenograft Model Antitumor Assays|Colon Cancer|Antibodies, Monoclonal|Cell Proliferation|Membrane Proteins|*Vaccines, DNA|Gene Expression Regulation, Neoplastic|Immunoglobulin G|Allografts|DNA 57 TM4SF5 30414479 Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2018 10.1016/j.cbpc.2018.11.003 0 0 0 210 *Silver|*Metal Nanoparticles|*Cell Lines|*Epithelial Cell|Oxidative Stress|Apoptosis|Metallothionein|Gene Expression Regulation|Gene Expression|Ions|*Biological Processes 57 TM4SF5 30217560 Cancer Lett. 2018 10.1016/j.canlet.2018.09.009 2 9 0 210 Liver Cancer|Carcinoma, Hepatocellular|CD44 protein, human|Hyaluronan Receptors|Signal Transduction|AC133 Antigen|Cancer Stem Cells|Phosphorylation|Cell Line, Tumor|Cell Proliferation|Upregulation|Membrane Proteins|Liver|Protein Tyrosine Phosphatases 57 TM4SF5 29749436 Int. J. Oncol. 2018 10.3892/ijo.2018.4385 4 0 0 210 Mice|Humans|Animals|*Colorectal Cancer|*Colon Cancer|Hepatocellular Carcinoma|Liver Neoplasms|Antibodies, Monoclonal|Membrane Proteins|Cell Line, Tumor|Prognosis|Xenograft Model Antitumor Assays|Cell Proliferation|Gene Expression Regulation, Neoplastic|TSPAN32 protein, human|*Tetraspanins|Disease Models, Animal|Immunohistochemistry|IgG2A|TM4SF5 protein, human 57 TMC2 30399700 Rev Sci Instrum 2018 10.1063/1.5036767 0 0 0 41 *X-Rays|*Radiography|Photons|Semiconductor|Electron|Microscopy 53 TMC2 30399697 Rev Sci Instrum 2018 10.1063/1.5039648 0 0 0 41 *X-Rays|Semiconductor|Laser|*Radiography|Oxides 53 TMC2 30308413 J Psychiatr Res 2018 10.1016/j.jpsychires.2018.09.020 7 0 0 41 Humans|*Asian Continental Ancestry Group|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Linkage Disequilibrium|Gene Frequency|Alleles|Genotype|Case-Control Studies|Calcium Channels 53 TMC2 30291150 Cold Spring Harb Perspect Med 2018 PMC6450785 10.1101/cshperspect.a033506 2 0 0 41 Humans|Mice|Animals|Mechanotransduction, Cellular|*Hair Cells, Auditory, Inner|Hair Cells, Auditory|Stereocilia|Membrane Proteins|Hearing|Mutation|Pcdh15 protein, mouse|Protein Precursors|Cadherins 53 TMC2 30138589 Neuron 2018 PMC6360533 10.1016/j.neuron.2018.07.033 40 0 0 41 Animals|Mice|*Mechanotransduction, Cellular|*Hair Cells, Auditory, Inner|Hair Cells, Vestibular|Hair Cells, Auditory|Membrane Proteins|*Vertebrate|Mice, Knockout|TMC1 protein, mouse 53 TMC2 30108254 Sci Rep 2018 PMC6092434 10.1038/s41598-018-28958-x 2 6 0 41 Mice|Animals|*Hair Cells, Auditory, Inner|Hair Cells, Cochlear|Hair Cells, Vestibular|*Vestibule, Labyrinth|Mechanotransduction, Cellular|Mice, Knockout|Hearing|Membrane Proteins|Disease Models, Animal|TMC1 protein, mouse|TMC2 protein, mouse 53 TMC2 30108230 Sci Rep 2018 PMC6092339 10.1038/s41598-018-29709-8 3 12 0 41 Mice|Animals|Deafness, Autosomal Recessive 7|*Hearing Loss, Sensorineural|*Hearing|Hair Cells, Vestibular|Hair Cells, Auditory|Hair Cells, Auditory, Inner|Cochlea|Deafness|Mechanotransduction, Cellular|*Disease Models, Animal|Membrane Proteins|Mutation|TMC1 protein, mouse|TMC2 protein, mouse 53 TMC2 29872055 Nat Commun 2018 PMC5988745 10.1038/s41467-018-04589-8 16 3 0 41 Mice|Animals|*Cochlea|Outer Hair Cells|Hair Cells, Auditory, Inner|Hair Cells, Vestibular|Stereocilia|Mechanotransduction, Cellular|Membrane Proteins|Animals, Newborn|Protein Isoforms|Calcium|TMC1 protein, mouse 53 TMC2 29395910 Neuron 2018 PMC7038793 10.1016/j.neuron.2017.12.041 8 1 0 41 Animals|*Caenorhabditis elegans|Caenorhabditis elegans Proteins|*Oviposition|TYRP1 protein, human|*Membrane Glycoproteins|Neurons|Muscles|Mutations|TMC-1 protein, C elegans|Ion Channels 53 TMC8 30156265 Int. J. Dermatol. 2018 10.1111/ijd.14196 3 0 0 65 Humans|*Epidermodysplasia Verruciformis|Papillomaviridae|Papillomavirus Infections|Mutations|Papilloma|Membrane Proteins|TMC8 protein, human 50 TMC8 30127996 Oncol Lett 2018 PMC6096185 10.3892/ol.2018.9104 2 3 0 65 Humans|Female|Human Papillomavirus Infection|Cervical Cancer|Cervical Intraepithelial Neoplasia|Papillomaviridae|Human papillomavirus 18|Human papillomavirus 16|DNA, Viral|Single Nucleotide Polymorphisms|Genotype 50 TMC8 30068544 J. Exp. Med. 2018 PMC6122964 10.1084/jem.20170308 17 34 0 65 Humans|*Keratinocytes|Epidermodysplasia Verruciformis|*Papillomaviridae|Papillomavirus Infections|Genetic Predisposition to Disease|Membrane Proteins|CIB1 protein, human|Calcium-Binding Proteins 50 TMC8 29968393 Cancer Sci. 2018 PMC6125479 10.1111/cas.13722 23 7 0 65 Humans|SDC3 protein, human|*Syndecan-3|Renal Cell Carcinoma|*Oncogenes|RNA, Micro|Kidney Neoplasms|RNA Interference|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Cell Line, Tumor|Down-Regulation|Gene Expression Profiling|MIRN144 microRNA, human 50 TMC8 29946305 Front Microbiol 2018 PMC6005841 10.3389/fmicb.2018.01222 12 0 0 65 Humans|Child|*Epidermodysplasia Verruciformis|*Papillomaviridae|Human Papillomavirus Infection|Mutations|Membrane Proteins 50 tmco1 30556256 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.60678 0 0 0 185 Humans|Male|Cerebrofaciothoracic Dysplasia|*Intellectual Disability|*Abnormalities, Multiple|Tooth Abnormalities|Phenotype|Musculoskeletal Abnormalities|*Dysostoses|Homozygote|Pedigree|Mutation 42 tmco1 30405695 Front Genet 2018 PMC6208000 10.3389/fgene.2018.00488 0 0 0 185 Humans|Glaucoma, Primary Open Angle|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Intraocular Pressure|Genotype|Visual Field|Cyclin-Dependent Kinase Inhibitor p15|Homeodomain Proteins 42 tmco1 30220460 Cell 2018 PMC6195207 10.1016/j.cell.2018.08.030 14 2 0 185 Chlorocebus aethiops|Animals|Humans|*Endoplasmic Reticulum|Endosomes|Golgi Apparatus|Protein Transport|Membrane Proteins|COS Cells|HeLa Cells 42 tmco1 29682451 Transl Sci Rare Dis 2018 PMC5904567 10.3233/TRD-180022 0 0 0 185 *Facial Recognition|*Abnormalities, Multiple|*Intellectual Disability|Pascual Castroviejo syndrome|*Hemangioma|*Brain Neoplasms|*Liver Neoplasms|*Dysostoses|*Thoracic Diseases|Musculoskeletal Abnormalities|Phenotype|Syndrome|Mutation 42 tmco1 29467381 Cell Death Differ. 2018 PMC6143536 10.1038/s41418-018-0067-x 6 4 0 185 Female|*Endoplasmic Reticulum|Granulosa Cells|Ovarian Follicle|Calcium Channels|Signal Transduction 42 tmco1 29401312 Hum. Mol. Genet. 2018 PMC6048986 10.1093/hmg/ddy040 6 3 0 185 Humans|*Exfoliation Syndrome|*Aqueous Humor|*Glaucoma, Primary Open Angle|Intraocular Pressure|miRNA|Cataract|Glaucoma|Biomarkers|MIRN-3144 microRNA, human 42 TMEFF1 29611532 Eur J Dermatol 2018 10.1684/ejd.2017.3210 1 1 0 69 Ichthyosis with hypotrichosis, autosomal recessive|*Mutation, Missense|Molecular Docking Simulation|*Hypotrichosis|Ichthyosis|matriptase|Serine Endopeptidases|Genes, Recessive|*Ichthyosis, Lamellar|Mutations|*Syndrome|Phenotype|Genetic Linkage|Pakistan 26 TMEM135 30279702 Front Genet 2018 PMC6153316 10.3389/fgene.2018.00396 1 1 0 40 Nonalcoholic Fatty Liver Disease|Lipid Metabolism|Hepatocytes|Liver|*Gene Expression|Triglycerides|Insulin Resistance|Liver Cirrhosis 20 TMEM135 30102730 PLoS ONE 2018 PMC6089435 10.1371/journal.pone.0201986 2 7 0 40 Mice|Animals|Mitochondrial Dynamics|Mitochondria, Heart|Mitochondrial Proteins|Myocytes, Cardiac|Mice, Transgenic 20 TMEM135 29706638 Eur. J. Hum. Genet. 2018 PMC6057984 10.1038/s41431-018-0149-8 0 0 0 40 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Genetic Linkage|Pedigree|Genome-Wide Association Study|*Dysplastic Nevus Syndrome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Genes, p16|Sweden 20 TMEM163 29532581 Addict Biol 2018 PMC6519128 10.1111/adb.12618 1 0 0 9 Humans|*Tobacco Use Disorder|*Genome-Wide Association Study|*Nicotine|Finland|Smoking|SNPs|Substance Withdrawal Syndrome|Genetic Predisposition to Disease|European Continental Ancestry Group|Cohort Studies|*Signal Transduction|Nerve Growth Factors 22 TMEM163 29301965 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC5789906 10.1073/pnas.1708207114 7 0 0 9 Humans|Proprotein Convertases|SNPs|Proprotein Convertase 9|Serine Endopeptidases|Receptors, LDL|Gene Frequency|Cholesterol, LDL|Genotype|Asian|Cohort Studies 22 TMEM165 30481169 PLoS Biol. 2018 PMC6258472 10.1371/journal.pbio.2006951 11 1 0 47 40 TMEM165 30307768 FASEB J. 2018 10.1096/fj.201800387R 3 4 0 47 40 TMEM165 30015898 Oncol. Rep. 2018 PMC6072395 10.3892/or.2018.6565 1 4 0 47 40 TMEM165 29954393 Cell Commun. Signal 2018 PMC6025805 10.1186/s12964-018-0246-x 4 20 0 47 40 TMEM165 29702557 Int J Mol Sci 2018 PMC5983582 10.3390/ijms19051304 7 37 0 47 40 TMEM165 29632074 J. Biol. Chem. 2018 PMC5971465 10.1074/jbc.RA118.002324 6 1 0 47 40 TMEM18 30570522 Nurs Res 2018 PMC6399059 10.1097/NNR.0000000000000337 0 0 0 59 Humans|Female|*African Americans|Menarche|European Continental Ancestry Group|Menopause|*Genomics|*Phenotype|Genome-Wide Association Study|*Reproduction|Genetic Loci|Polymorphism, Single Nucleotide|Genetic Variation|Risk Factors|Age Factors|*Disease Susceptibility|Cardiovascular Diseases 135 TMEM18 30341978 Med. Sci. Monit. 2018 PMC6204654 10.12659/MSM.907180 1 0 0 59 Child|Adolescent|Humans|*Adiposity|*Obesity|*Lifestyle|Weight Loss|Overweight|Body Mass Index|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Genotype|Polymorphism, Single Nucleotide|TMEM18 protein, human|Membrane Proteins 135 TMEM18 30311592 Br. J. Nutr. 2018 10.1017/S0007114518002738 0 0 0 59 Child|Adolescent|Humans|Cross-Sectional Studies|*Fibronectin Type III Domain|Waist Circumference|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|*Anthropometry|Body Mass Index|Childhood Obesity|Genetic Predisposition to Disease|Alleles|Polymorphism, Single Nucleotide|Genotype|*Risk Factors|Body Fat|Brazil|FTO protein, human|FNDC5 protein, human|Fibronectins 135 TMEM18 30199869 Acta Haematol. 2018 10.1159/000492742 3 0 0 59 Humans|*Prognosis|*Leukemia, Myeloid, Acute|Area Under Curve|Kaplan-Meier Estimate|ROC Curve|Biomarkers, Tumor|MicroRNAs|Membrane Proteins|TMEM18 protein, human 135 TMEM18 30026463 Nutr Diabetes 2018 PMC6053407 10.1038/s41387-018-0050-0 1 1 0 59 Humans|Genome-Wide Association Study|*African Continental Ancestry Group|*African Americans|*Body Composition|European Continental Ancestry Group|Adiposity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Obesity|Waist Circumference|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Body Mass Index|Genetic Loci|Genotype|Phenotype 135 TMEM18 29441128 Mol Cytogenet 2018 PMC5800070 10.1186/s13039-018-0363-7 4 0 0 59 Humans|*Obesity|Prader-Willi Syndrome|DNA Copy Number Variations|*Microarray Analysis|Phenotype|Comparative Genomic Hybridization|Chromosome Deletion|*Chromosomes B 135 TMEM38B 30282030 Cell Rep 2018 PMC6251307 10.1016/j.celrep.2018.09.013 8 10 0 37 Animals|Mice|*Unfolded Protein Response|X-Box Binding Protein 1|Endoplasmic Reticulum Stress|Endoribonucleases|Endoplasmic Reticulum|Tunicamycin|Protein-Serine-Threonine Kinases|Transcription Factor|Signal Transduction|Gene Expression Regulation|*Antineoplastic Agents|RNA, Messenger|Cell Line|Xbp1 protein, mouse 25 TMEM38B 29963229 Oncotarget 2018 PMC6021234 10.18632/oncotarget.25455 3 7 0 37 Swine|Animals|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|Genome-Wide Association Study|Swine, Miniature|Chromosome Mapping|Quantitative Trait Loci|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Disease Progression 25 TMEM70 30114719 Neuropediatrics 2018 10.1055/s-0038-1667345 1 0 0 63 Humans|Infant, Newborn|3-Methylglutaconic Aciduria|*Inborn Errors of Metabolism|Disorders, Mitochondrial|*Epilepsy|*Movement Disorders|3-methylglutaconic acid|Glutarates|Exome|Mutations|*Recognition, Psychology 44 TMEM70 29978770 Cardiol Young 2018 10.1017/S1047951118000860 0 0 0 63 Humans|*Cardiomyopathy, Hypertrophic, Familial|*Echocardiography, Three-Dimensional|Cardiac Myosins|*Chinese|Phenotypes|Heterozygote|Myosin Heavy Chains|Cardiomyopathy, Hypertrophic|DNA Mutational Analysis|Pedigree|Echocardiography|Mutations, Missense|Genetic Predisposition to Disease|Mutation|Long QT Syndrome|Electrocardiography|*Cardiomyopathies 44 TNFAIP2 30145807 J. Cell. Mol. Med. 2018 PMC6201362 10.1111/jcmm.13822 6 48 0 118 Humans|Cell Proliferation|Signal Transduction|NF-kappa B|Transcription Factor RelA|Tumor Necrosis Factor-alpha|Cell Line, Tumor|Cytokines|Gene Expression Regulation, Neoplastic|Apoptosis|Neovascularization, Pathologic|TNFAIP2 protein, human 64 TNFAIP2 29596155 Neuroreport 2018 10.1097/WNR.0000000000001013 2 4 0 118 64 TNFAIP2 29373860 Environ. Health Perspect. 2018 PMC6014712 10.1289/EHP2192 19 15 0 118 Humans|Pregnancy|Female|*Cadmium|*Epigenome|*Placenta|Maternal Exposure|Fetal Development|Birth Weight|DNA Methylation|Epigenesis, Genetic|Environmental Pollutants|Hazardous Substances 64 TNP1 30551142 Hum. Reprod. 2018 10.1093/humrep/dey357 0 0 0 248 Humans|Male|Semen Analysis|*Sperm|Sperm Count|Sperm Motility|Infertility, Male|DNA Fragmentation|*Aging 93 TNP1 30528522 Reprod Biol 2018 10.1016/j.repbio.2018.11.005 0 2 0 248 Humans|Male|Rats|Animals|*Leydig Cells|*Epididymis|*Testosterone|ethylene dimethanesulfonate|*Mesylates|Testis|Vasectomy|Spermatids|*Testosterone Congeners|*Genital Diseases, Male|*Granuloma 93 TNP1 30370952 Reprod. Domest. Anim. 2018 10.1111/rda.13369 0 0 0 248 Humans|Cattle|Male|Animals|*Sperm Motility|Spermatozoa|Infertility, Male|Spermiogenesis|3' UTR|Chromosomal Proteins, Non-Histone|Polymorphism, Single Nucleotide|PCR|mRNA|Gene Expression 93 TNP1 30087569 Infect Drug Resist 2018 PMC6061673 10.2147/IDR.S159345 0 2 0 248 beta-Lactamases|Plasmids|Escherichia coli Infections|Escherichia coli|Cephalosporins|Gene Transfer, Horizontal|Anti-Bacterial Agents 93 TNP1 30054974 Andrology 2018 10.1111/andr.12528 2 0 0 248 Humans|Male|*Sperm Retrieval|*Testis|*Azoospermia|Spermatozoa|*Biomarkers 93 TNP1 29929354 J. Vet. Sci. 2018 PMC6167331 10.4142/jvs.2018.19.5.592 0 0 0 248 Male|Spermatogonia|Adult Germline Stem Cells|Spermatogenesis|Testis|Cell Differentiation 93 TNP1 29866902 Development 2018 PMC6053656 10.1242/dev.164855 6 0 0 248 Mice|Male|Animals|*Testis|*Haploidy|*Spermiogenesis|Spermatocytes|*Meiosis|Spermatids|SOX Transcription Factors|Gene Expression Regulation|Cell Differentiation|sox30 protein, mouse 93 TNP1 29526266 Sci. Justice 2018 10.1016/j.scijus.2017.09.002 1 0 0 248 Male|*Messenger RNA|Semen|Cervix Mucus|Forensic Genetics|DNA Fingerprinting|Saliva|Body Fluids|Genetic Markers|Spermatozoa|Gene Expression Profiling|Menstruation 93 TNP1 29397043 Iran. Biomed. J. 2018 PMC5949128 10.22034/ibj.22.4.258 1 0 0 248 Mice|Animals|Male|*Testis|Spermatogenesis|Seminiferous Tubules|Spermatogonia|Spermatozoa|Meiosis|Organ Culture|spermatid transition proteins|*Chromosomal Proteins, Non-Histone|Apoptosis 93 TNP1 29305944 Urology 2018 10.1016/j.urology.2017.12.023 0 0 0 248 Humans|Male|*Sperm Retrieval|*Testis|*Azoospermia|Spermatozoa|*Inferior Colliculi 93 TNP2 30551142 Hum. Reprod. 2018 10.1093/humrep/dey357 1 0 0 42 Humans|Male|Semen Analysis|*Sperm|Sperm Count|Sperm Motility|Infertility, Male|DNA Fragmentation|*Aging 118 TNP2 30370952 Reprod. Domest. Anim. 2018 10.1111/rda.13369 0 0 0 42 Humans|Cattle|Male|Animals|*Sperm Motility|Spermatozoa|Infertility, Male|Spermiogenesis|3' UTR|Chromosomal Proteins, Non-Histone|Polymorphism, Single Nucleotide|PCR|mRNA|Gene Expression 118 TNP2 30087569 Infect Drug Resist 2018 PMC6061673 10.2147/IDR.S159345 0 2 0 42 beta-Lactamases|Plasmids|Escherichia coli Infections|Escherichia coli|Cephalosporins|Gene Transfer, Horizontal|Anti-Bacterial Agents 118 TNP2 29731491 J. Reprod. Dev. 2018 PMC6105735 10.1262/jrd.2018-024 0 4 0 42 Male|Female|Mice|Animals|*Oocytes|Oogenesis|*Spermatogenesis|Ovaries|Germ Cells|Embryonic Development|Gene Expression Regulation, Developmental|Transcription Factors|Mice, Transgenic|mRNA|Cell Differentiation|Cell Nucleus|Tnp2 protein, mouse|Nuclear Proteins 118 TNPO3 30247649 Rheumatology (Oxford) 2018 10.1093/rheumatology/key281 1 0 0 229 Humans|*Genome-Wide Association Study|Iran|Turkey|*Sclerosis, Systemic|Genetic Predisposition to Disease|HLA-DP beta-Chains|Polymorphism, Single Nucleotide|Gene Frequency|European Continental Ancestry Group|Genotype|Case-Control Studies|Interferon Regulatory Factors 81 TNPO3 29526438 Cytokine Growth Factor Rev. 2018 10.1016/j.cytogfr.2018.02.006 3 0 0 229 Humans|*Nuclear Envelope|*HIV Infections|HIV-1|*Cell Nucleus|Nuclear Import|Nucleoporins|Virus Integration|Virus Replication|Cyclophilin A|DNA, Viral|Capsid Proteins|Host-Pathogen Interactions|Macrophages|Cell Line|TNPO3 protein, human|beta Karyopherins 81 TNPO3 29329553 Retrovirology 2018 PMC5767004 10.1186/s12977-018-0389-2 4 8 0 229 Humans|transportin SR2|*Active Transport, Cell Nucleus|p31 integrase protein, Human immunodeficiency virus 1|*HIV Integrase|*beta Karyopherins|HIV-1|HIV Infections|Virus Replication|Protein Binding|Antivirals|Cell Nucleus 81 TNS1 30312486 Acta Obstet Gynecol Scand 2018 10.1111/aogs.13481 1 2 0 410 Humans|Female|*Endometriosis|*Down-Regulation|*Tensins|Endometrium|Gonadotropin-Releasing Hormone|RNA, Messenger 79 TNS1 30127601 Int J Chron Obstruct Pulmon Dis 2018 PMC6089098 10.2147/COPD.S173206 7 5 0 410 *Transcriptome|*Computational Biology|*Sequencing, Next-Generation|*Epithelium|Epithelial Cells|Bronchi|Pulmonary Disease, Chronic Obstructive|Lung|MicroRNAs 79 TNS1 29961123 J Mater Sci Mater Med 2018 PMC6028859 10.1007/s10856-018-6113-x 3 0 0 410 *Hydrogels|*Mesenchymal Stem Cells|*Alginate|Poly(amidoamine)|Polyamines|Tissue Engineering|Biomaterial|Tissue Scaffolds|Cell Differentiation|Hexuronic Acids|Cells, Cultured|Regenerative Medicine|Cell Survival 79 TNS1 29949718 Am. J. Respir. Cell Mol. Biol. 2018 PMC6236690 10.1165/rcmb.2018-0088OC 6 0 0 410 Humans|Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|White|Smoking|Lung|*Sequencing, Whole Genome|Case-Control Studies|African Americans|Boston 79 TNS1 29668032 J. Orthop. Res. 2018 10.1002/jor.24025 1 0 0 410 *Anterior Cruciate Ligament Injuries|*Transcriptome|Tibial Meniscus Injuries|Anterior Cruciate Ligament Reconstruction|Knee Joint|*Microarray Analysis|Meniscus 79 TNS1 29416680 Oncotarget 2018 PMC5787423 10.18632/oncotarget.23275 6 14 0 410 Humans|transgelin|*Microfilament Proteins|*Muscle Proteins|*Colorectal Cancer|Prognosis|Cell Motility|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Colonic Neoplasms|Cell Proliferation|Down-Regulation 79 TONSL 29478807 Mol. Cell 2018 PMC5843376 10.1016/j.molcel.2018.01.031 11 37 0 109 Humans|*Histone Chaperones|*Homologous Recombination|*DNA, Single-Stranded|Rad51 Recombinase|DNA-Binding Proteins|DNA Repair|Nuclear Proteins|Chromatin|DNA Breaks, Double-Stranded|Histones|Cell Cycle Proteins|Chromatin Assembly|DNA Replication|*Chromatin Assembly Factor-1|NF-kappa B|Protein Binding|RAD51 protein, human|ASF1A protein, human 28 TOR2A 30311629 Singapore Med J 2018 PMC6482418 10.11622/smedj.2018123 1 0 0 254 Humans|*Atherosclerosis|*Renal Dialysis|Intercellular Signaling Peptides and Proteins|Inflammation|Case-Control Studies 64 TOR2A 30017195 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.07.059 2 2 0 254 Mice|Animals|*Neuroprotective Agents|*Parkinson Disease|Dopaminergic Neurons|Substantia Nigra|1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|Neuroprotection|Mice, Inbred C57BL|Mesencephalon|Disease Models, Animal|Neuropeptide 64 TOR2A 29883365 Aging (Albany NY) 2018 PMC6046244 10.18632/aging.101461 2 3 0 254 Humans|Middle Aged|Aged, 80 and over|*Genome-Wide Association Study|*DNA Copy Number Variations|*Longevity|*Asian Continental Ancestry Group|Genome, Human|Phenotypes|Ethnic Groups 64 TOR2A 29879880 Curr. Pharm. Des. 2018 10.2174/1381612824666180607124531 0 0 0 254 Child|Adolescent|Humans|*Hypertension|Atherosclerosis|Arginine|Endothelium, Vascular|Case-Control Studies 64 TOR2A 29770609 Mol Genet Genomic Med 2018 PMC6081235 10.1002/mgg3.411 5 6 0 254 *Blepharospasm|*Whole Exome Sequencing|Dystonia, Focal|Dystonia|Mutation 64 TOR2A 29728799 Cancer Chemother. Pharmacol. 2018 10.1007/s00280-018-3594-8 5 0 0 254 Humans|*Neoadjuvant Therapy|DNA Topoisomerases, Type II|Receptor, ErbB-2|Chemotherapy, Adjuvant|Anthracyclines|Gene Amplification|Antigens, Neoplasm|Poly-ADP-Ribose Binding Proteins|Antineoplastic Combined Chemotherapy Protocols|Epirubicin|Biomarkers, Tumor|Disease-Free Survival|In Situ Hybridization, Fluorescence|DNA-Binding Proteins|CCL18 protein, human|*Chemokines, CC|*Macrophages 64 TOR2A 29359008 Oxid Med Cell Longev 2018 PMC5735326 10.1155/2017/6905217 3 30 0 254 Animals|NF-kappa B|Human Umbilical Vein Endothelial Cells|Signal Transduction|Diabetes Mellitus, Experimental|Oxidative Stress|Intercellular Signaling Peptides and Proteins|Cells, Cultured 64 tppp3 30404076 Cell. Physiol. Biochem. 2018 10.1159/000494892 1 6 0 109 *Carcinoma, Non-Small-Cell Lung|*Lung Cancer|TWIST1 protein, human|*Twist-Related Protein 1|*Nuclear Proteins|STAT3 protein, human|*STAT3 Transcription Factor|*Cell Proliferation|Biomarkers, Tumor|Cell Line, Tumor|Cell Movement|Oncogene|*Neoplastic Processes|Apoptosis|*Neoplasms, Second Primary 22 tppp3 29901777 Biol. Reprod. 2018 10.1093/biolre/ioy136 0 10 0 109 Pregnancy|Female|Humans|*Implantation, Embryo|*Uterus|Blastocyst|Endometrium|*Catenins|WNT4 protein, human|Wnt4 Protein|Estradiol|beta Catenin|Signal Transduction 22 tppp3 29515771 Oncotarget 2018 PMC5839402 10.18632/oncotarget.23929 9 22 0 109 Humans|*Prognosis|*Proteomics|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Upregulation|CDH17 protein, human|Cadherins|CLIC3 protein, human|Chloride Channels|LGALS4 protein, human|Galectin 4 22 tppp3 29311254 Hypertension 2018 PMC5877117 10.1161/HYPERTENSIONAHA.117.10527 1 7 0 109 Male|Female|*Blood Pressure|*Transcriptome|*Blood Pressure Determination|Hypertension|Genome-Wide Association Study|Transcriptome Analysis|Phenotype|Genotype|Cohort Studies|Finland 22 TRAK2 30111583 J. Cell. Sci. 2018 10.1242/jcs.219469 10 1 0 105 Animals|*Mitochondria|*Carrier Proteins|Mitochondrial Membrane, Outer|Mitochondrial Proteins|Kinesin|Dynein|rho GTP-Binding Proteins|Neurons|Microtubules|Biological Transport|Myosins 46 TRAK2 30001398 PLoS ONE 2018 PMC6042722 10.1371/journal.pone.0200417 1 1 0 105 Animals|Mice|*Down-Regulation|Autism Spectrum Disorder|Amacrine Cells|Retina|Retinal Ganglion Cells|Synaptic Transmission|*RNA Splicing|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Depth Perception|Rbfox1 protein, mouse|RNA Splicing Factors|Rbfox2 protein, mouse 46 TRAK2 29992963 Nat Commun 2018 PMC6041267 10.1038/s41467-018-05087-7 5 9 0 105 ADP-ribosylation factor 6|*ADP-Ribosylation Factors|*Cell Movement|*Mitochondria|Signal Transduction|Adaptor Proteins, Signal Transducing|Guanine Nucleotide Exchange Factors|RNA, Small Interfering|Focal Adhesions|Reactive Oxygen Species|*Protein Transport|Integrins|Oxidative Stress 46 TRAK2 29671888 Clin Cardiol 2018 PMC6489891 10.1002/clc.22969 1 0 0 105 Humans|dofetilide|*Atrial Fibrillation|*Genetic Markers|*Pilot Projects|*Whole Exome Sequencing|*Phenethylamines|*Sulfonamides|Anti-Arrhythmia Agents|Atrial Flutter|Long QT Syndrome|Electrocardiography|*Microsatellite Markers|Treatment Outcome|*DNA 46 TRAK2 29311115 EMBO J. 2018 PMC5793800 10.15252/embj.201696380 27 19 0 105 Mice|Animals|*Actins|Mitochondrial Membrane, Outer|*Microtubule|Mitochondria|Mitochondrial Proteins|parkin protein|Ubiquitin-Protein Ligases|rho GTPases|Mitophagy|*Biological Transport|Dynein|TYRP1 protein, human|*Membrane Glycoproteins|Kinesin|Myosin|Protein Transport|Protein Kinases|Trak1 protein, mouse 46 TRIOBP 30195749 Mol Ther Nucleic Acids 2018 PMC6023786 10.1016/j.omtn.2018.04.008 1 1 0 239 Male|Animals|Mice|*Up-Regulation|Mice, Nude|*Mice, Inbred BALB C|3' UTR|MicroRNAs|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|RNA Interference|Sp1 Transcription Factor|Lung Neoplasms|*Neoplastic Processes|*Transcriptional Activation|Cell Proliferation|Cell Line, Tumor 61 TRIOBP 30140248 Front Neurol 2018 PMC6094994 10.3389/fneur.2018.00582 2 0 0 239 61 TRIOBP 30089789 Mol. Psychiatry 2018 10.1038/s41380-018-0133-2 10 0 0 239 Animals|Humans|collapsin response mediator protein-1|Nerve Tissue Proteins|Dysbindin-1|Protein Aggregation, Pathological|TYRP1 protein, human|*Membrane Glycoproteins|Schizophrenia|Brain|Proteostasis|Neurons|Neurodegenerative Diseases|*Chronic Disease|Phosphoproteins 61 TRIOBP 30064533 Twin Res Hum Genet 2018 10.1017/thg.2018.41 2 0 0 239 Female|Humans|*Pedigree|DNA Copy Number Variations|*Monozygotic Twins|Twins, Dizygotic|Monozygotic Twinning|*Sequencing, Whole Genome|Phenotype|DNA, Mitochondrial|*Reproductive History 61 TRIOBP 29890989 Cell Commun. Signal 2018 PMC5996455 10.1186/s12964-018-0237-y 1 11 0 239 Humans|F-actin-binding proteins|*Microfilament Proteins|*Carrier Proteins|Actin Cytoskeleton|Actins|Cytoskeleton|Nonsyndromic Deafness|Deafness|Mutation 61 TRIOBP 29568747 Biomed Res Int 2018 PMC5820677 10.1155/2018/3103986 2 1 0 239 Humans|*Sequencing, Next-Generation|Nonsyndromic Deafness|Deafness|Hearing Loss|*Genetic Linkage|Connexins|Pedigree|Hearing Loss, Sensorineural|Mutation 61 TRIOBP 29507111 J. Cell. Sci. 2018 PMC5897710 10.1242/jcs.206730 2 5 0 239 Humans|Ether-A-Go-Go Potassium Channels|Long QT Syndrome|Myocytes, Cardiac|Action Potentials|HEK293 Cells|TRIOBP protein, human|Microfilament Proteins 61 TRIOBP 29363730 Mol Med Rep 2018 PMC5802229 10.3892/mmr.2018.8458 1 4 0 239 Humans|*Glioblastoma|F-actin-binding proteins|*Microfilament Proteins|*Carrier Proteins|TRIO protein, human|*Guanine Nucleotide Exchange Factors|*Protein-Serine-Threonine Kinases|Cell Movement|Brain Neoplasms|Cell Proliferation|Cell Line, Tumor|RNA, Small Interfering 61 TSHZ1 30104253 Mol. Cell. Biol. 2018 PMC6189455 10.1128/MCB.00217-18 0 4 0 48 *Retinoic Acid|Embryonal Carcinoma Cells|Differentiations, Cell|Neurons|Promoter Regions, Genetic|Cell Line, Tumor 42 TSPY1 29974883 Asian J. Androl. 2018 PMC6498724 10.4103/aja.aja_43_18 1 0 0 100 Male|Female|Humans|*Testis|Cell Cycle Proteins|Gonadoblastoma|AR protein, human|Androgen Receptor|Transcription Factors|Nuclear Proteins|DNA-Binding Proteins|CDC2 Protein Kinase|*Oncogenesis|Genes, cdc|Chromosomes, Human, Y|Cyclin B1|Transcriptional Activation|Cell Proliferation|Ovarian Neoplasms 125 TSPY1 29748603 Cell Death Dis 2018 PMC5945610 10.1038/s41419-018-0589-7 4 51 0 100 Humans|Male|Mice|Animals|USP7 protein, human|*Ubiquitin-Specific Peptidase 7|*Spermatogonia|*Tumor Suppressor Protein p53|Ubiquitylation|Signal Transduction|Cell Proliferation|Cell Cycle Proteins|Nuclear Proteins|Apoptosis|Cell Line, Tumor|Spermatogenesis|TSPY1 protein, human|TSPYL5 protein, human 125 TTC12 30104163 Eur Neuropsychopharmacol 2018 PMC6525784 10.1016/j.euroneuro.2018.07.101 0 0 0 11 Adult|Humans|Adolescent|*Smoking|*Reward|Receptors, Dopamine D2|Tobacco Use Disorder|Allele|*Tobacco Smoking|Polymorphism, Single Nucleotide|Genotype|Genetic Variation|*Neurobiology|Protein-Serine-Threonine Kinases|TTC12 protein, human|Proteins|ANKK1 protein, human|DRD2 protein, human 24 TTC7A 30553809 Cell Mol Gastroenterol Hepatol 2018 PMC6406079 10.1016/j.jcmgh.2018.12.001 4 6 0 51 Humans|Child|Intestinal Atresia, Multiple|Intestinal Atresia|*Intestines|Inflammatory Bowel Disease|Phenotypes|Pedigree|Enterocolitis|Proteins|Mutation|Cohort Studies|TTC7A protein, human 34 TTC7A 30455981 Cell Discov 2018 PMC6232119 10.1038/s41421-018-0061-y 2 1 0 51 Humans|*Tetratricopeptide Repeat|Intestines|Intestinal Atresia|Mutation|Pedigree|Apoptosis|Chromatin|TTC7A protein, human|Proteins 34 TTC7A 30111818 Oncogene 2018 PMC6336684 10.1038/s41388-018-0448-0 3 34 0 51 Humans|Male|CXCR4 protein, human|*Receptors, CXCR4|*Prostate|*Phosphatidylinositol 4-Kinase|Proteomics|CXCL12 protein, human|Chemokine CXCL12|*Prostate Cancer|*Signal Transduction|Cell Migration|Bone Neoplasms|Cell Line, Tumor|Membrane Microdomains|phosphatidylinositol 4-phosphate|Phosphatidylinositol Phosphates|Androgens|PC3 Cell Line|Plasma Membrane 34 TTC7A 30031006 J. Mol. Biol. 2018 10.1016/j.jmb.2018.07.020 2 2 0 51 *Phosphatidylinositol 4-Kinase|phosphatidylinositol 4-phosphate|Phosphatidylinositol Phosphates|Plasma Membrane|Viral Nonstructural Proteins|Membrane Proteins|Hepacivirus|Virus Replication|*Mitochondrial Membranes|Host-Pathogen Interactions 34 TTC7A 29980668 Nat Commun 2018 PMC6035235 10.1038/s41467-018-05105-8 3 19 0 51 Animals|*Zebrafish|*PI3-Kinase|*Inflammatory Bowel Disease|Zebrafish Proteins|*Phosphatidylinositol 3-Kinase|PIK3CG protein, human|*Class Ib Phosphatidylinositol 3-Kinase|Embryo, Nonmammalian|Intestinal Epithelium|CDH1 protein, human|E Cadherin|Larva|Microbiota, Gut|Cells, Epithelial|Phenotype|Inflammation|Antigens, CD 34 TTC7A 29921470 Arch Pediatr 2018 10.1016/j.arcped.2018.05.006 1 0 0 51 Humans|Intestinal Atresia, Multiple|*Intestinal Atresia|*Inflammatory Bowel Disease|*Mutation|Intestines|Immunodeficiency, Severe Combined|Proteins|TTC7A protein, human 34 TTC7A 29879038 Medicine (Baltimore) 2018 PMC5999454 10.1097/MD.0000000000010939 1 1 0 51 *Intestinal Atresia|Immunodeficiency, Severe Combined|Genetic Association Studies|*Sepsis|Exome|Pedigree|Genetic Predisposition to Disease|Mutation|Proteins|Intestinal Obstruction 34 TTC7A 29775636 J. Allergy Clin. Immunol. 2018 10.1016/j.jaci.2018.02.057 1 1 0 51 Humans|Mice|Animals|*Tetratricopeptide Repeat|*Lymphocytes|*Dermatitis|Phenotype|Mutations|Psoriasis|*Fibroblasts|Cell Proliferation|TTC7A protein, human|Proteins 34 TTC7A 29505141 JPEN J Parenter Enteral Nutr 2018 10.1002/jpen.1013 1 0 0 51 Infant|Humans|Infant, Newborn|*Severe Combined Immunodeficiency|Newborn Screening|Receptors, Antigen, T-Cell|Lymphopenia|Intestinal Atresia, Multiple|Intestinal Atresia|*Intestines|Mutations|Massachusetts|TTC7A protein, human|Proteins 34 TTI2 30484153 Adv. Exp. Med. Biol. 2018 10.1007/978-3-030-00737-9_5 2 0 0 57 Humans|Animals|prefoldin|Cryoelectron Microscopy|*Molecular Chaperones|Saccharomyces cerevisiae|HSP90 Heat-Shock Proteins|Saccharomyces cerevisiae Proteins|PRKDC protein, human|Nuclear Proteins|Carrier Proteins|DNA Helicases|ATPases Associated with Diverse Cellular Activities|Multiprotein Complexes|snoRNP|RNA Polymerase II|Protein Binding|Binding Sites|mTOR Protein|DNA-Activated Protein Kinase 25 TTI2 29470645 Curr. Genet. 2018 PMC6842304 10.1007/s00294-018-0817-9 5 0 0 57 Animals|*Phosphatidylinositol 3-Kinase|transformation-transcription domain-associated protein|Nuclear Proteins|MTOR protein, human|TOR Serine-Threonine Kinases|Saccharomyces cerevisiae Proteins|Telomere-Binding Proteins|Molecular Chaperone|Saccharomyces cerevisiae|HSP90 Heat-Shock Proteins|Phosphorylation|Protein Binding|DNA-Activated Protein Kinase|Adaptor Proteins, Signal Transducing|Tel2 protein, S cerevisiae|PIH1 protein, S cerevisiae 25 TWSG1 30125619 Matrix Biol. 2018 PMC6456722 10.1016/j.matbio.2018.08.006 1 8 0 895 Humans|Animals|*Gastrulation|*Bone Morphogenetic Proteins|BMP4 protein, human|Bone Morphogenetic Protein 4|Signal Transduction|Zebrafish Proteins|Carrier Proteins|Neovascularization, Physiologic|Protein Binding|Zebrafish|Endothelial Cells|Cells, Cultured|BMPER protein, human 47 TWSG1 30122583 Taiwan J Obstet Gynecol 2018 10.1016/j.tjog.2018.06.019 1 0 0 895 Pregnancy|Female|Humans|Adolescent|Chromosome 18p deletion syndrome|*Turner Syndrome|*Chromosome Disorders|*Chromosome Deletion|*Chromosomes, Human, Pair 18|*Dwarfism|Comparative Genomic Hybridization|Amniocentesis|Cytogenetic Analysis|Intellectual Disability|In Situ Hybridization, Fluorescence|*Elbow Joint 47 TWSG1 30021131 Gene 2018 10.1016/j.gene.2018.07.040 0 0 0 895 Horses|Animals|*Transcriptome|*RNA-Seq|Physical Conditioning, Animal|Gene Expression Profiling|*Bone Remodeling|*Whole Exome Sequencing|Biomarkers 47 TWSG1 29756996 DNA Cell Biol. 2018 10.1089/dna.2018.4188 2 0 0 895 *Stomach Neoplasms|*Genes, Tumor Suppressor|Neoplasm Invasiveness|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Cycle|Cell Movement|Cell Line, Tumor|Apoptosis|Real Time PCR|Biomarkers, Tumor|Western Blotting|China 47 TWSG1 29654706 FEBS J. 2018 PMC5947552 10.1111/febs.14439 1 2 0 895 Animals|*Bone Morphogenetic Proteins|*Endothelial Cell|*Signal Transduction|*Cell Differentiation|Receptor, BMP|Zebrafish Proteins|Carrier Proteins|Neovascularization, Physiologic|Zebrafish|Ephrin-B2|RNA, Small Interfering 47 TWSG1 29544220 Cytogenet. Genome Res. 2018 10.1159/000487371 2 0 0 895 Humans|Female|Chromosome 18p deletion syndrome|*Chromosomes, Human, Pair 18|*Growth Hormone|*Chromosome Disorders|*Chromosome Deletion|*Phenotype|*Human Growth Hormone|Karyotyping|*Pituitary Hormones, Anterior|Chromosome Banding|Genotype|Craniofacial Abnormalities|Intellectual Disability|In Situ Hybridization, Fluorescence|Genotype-Phenotype Correlation 47 TWSG1 29543343 Eur. J. Haematol. 2018 10.1111/ejh.13062 3 2 0 895 Mice|Animals|HAMP protein, human|*Hepcidins|Erythropoiesis|Iron|*Disease Models, Animal|Erythropoietin|*Hypoxia|Mice, Inbred C57BL|Hepatocytes|Liver|Cytokines|Muscle Proteins 47 TWSG1 29473997 FEBS J. 2018 10.1111/febs.14414 3 4 0 895 Humans|Animals|*Zebrafish|*Endothelial Cells|*Gastrulation|*Signal Transduction|Zebrafish Proteins|Bone Morphogenetic Protein|BMP4 protein, human|Bone Morphogenetic Protein 4|Neovascularization, Physiologic|Carrier Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Gene Expression Regulation, Developmental|In Situ Hybridization|siRNA|Morpholinos|BMPER protein, human 47 txnl1 30433779 J. Am. Chem. Soc. 2018 10.1021/jacs.8b08606 1 1 0 480 Humans|*Proteome|Proteomics|Chromatography, Liquid|HeLa Cells|*Reagents|Tandem Mass Spectrometry|*Endoplasmic Reticulum|Isotope Labeling, Stable|Endoplasmic Reticulum Stress|Tunicamycin|Unfolded Protein Response|Amino Acids|Transcription Factors|TXNL1 protein, human|Thioredoxins 37 txnl1 30348842 Mol. Cell. Biol. 2018 PMC6290375 10.1128/MCB.00426-18 8 3 0 480 Mice|Animals|*Proteasome Endopeptidase Complex|Ubiquitin|Proteolysis|Ubiquitination|enhanced green fluorescent protein|Green Fluorescent Proteins|Ubiquitin Thiolesterase|Cytoplasm 37 txnl1 30290847 Vet. Res. 2018 PMC6389150 10.1186/s13567-018-0599-6 1 34 0 480 Animals|Chick Embryo|*Newcastle disease virus|Newcastle Disease|Viral Proteins|*Apoptosis|Virus Replication|*Downregulation|Chicken|CASP3 protein, human|Caspase 3|TYRP1 protein, human|*Membrane Glycoproteins|Cell Line|Host-Pathogen Interactions|Yeast Two-Hybrid System|Fibroblasts|Western Blotting 37 txnl1 29427717 Fish Shellfish Immunol. 2018 10.1016/j.fsi.2018.02.009 0 1 0 480 Animals|*Seahorse|Streptococcus iniae|Edwardsiella tarda|Fish Proteins|Fish Diseases|Enterobacteriaceae Infections|Immunity, Innate|Sequence Alignment|TXN protein, human|Thioredoxin|Poly I-C|Streptococcal Infections|Amino Acid Sequence|Gene Expression Regulation|Gene Expression Profiling|Lipopolysaccharides|Phylogeny|Cloning, Molecular 37 UBAP2L 30536073 Curr Med Sci 2018 10.1007/s11596-018-1987-x 2 3 0 157 Rats|Animals|*Mesenchymal Stem Cells|*Up-Regulation|*Injury, Spinal Cord|*Recovery of Function|Mesenchymal Stem Cell Transplantation|Cell Differentiation|Rats, Sprague-Dawley|Neurons|Cells, Cultured|CASP3 protein, human|Caspase 3|Cell Survival|Apoptosis|Astrocytes|Cell Proliferation|*Transcriptional Activation 21 UBAP2L 30291221 Med. Sci. Monit. 2018 PMC6284357 10.12659/MSM.912861 1 4 0 157 *Carcinoma, Hepatocellular|*Liver Neoplasms|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|Cell Proliferation|Signal Pathway|Cell Migration|Hep G2 Cells|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Downregulation|*Neoplastic Processes|Apoptosis|Upregulation|RNA Interference|Genes, cdc|Ubiquitins 21 UBAP2L 29395067 Mol. Cell 2018 10.1016/j.molcel.2017.12.020 76 0 0 157 Humans|*mRNA|Cytoplasmic Granules|Cytoplasm|RNA-Binding Proteins|RNA|Carrier Proteins|Stress, Physiological|HeLa Cells|CSDE1 protein, human|DNA-Binding Proteins|Ubap2L protein, human 21 ULK4 30086552 Cytogenet. Genome Res. 2018 10.1159/000491871 1 0 0 17 Male|Humans|Child|Adolescent|Young Adult|Adult|*Siblings|Intellectual Disability|Comparative Genomic Hybridization|Chromosomes, Human, X|Phenotype|*Obesity|DNA Copy Number Variations|Hearing Loss|Epilepsy|Ulk4 protein, human|Protein-Serine-Threonine Kinases|BRWD3 protein, human|Transcription Factors 27 ULK4 29391390 Transl Psychiatry 2018 PMC5804027 10.1038/s41398-017-0091-5 2 3 0 17 Animals|Humans|DNA Copy Number Variations|*Anxiety|GABAergic Neurons|*Signal Transduction|Interneurons|Serine Threonine Kinase|Behavior, Animal|Hippocampus|Disease Models, Animal|Schizophrenia|Autism Spectrum Disorder|Intellectual Disability|Ulk4 protein, human 27 UPK1A 30563733 J. Dermatol. Sci. 2018 10.1016/j.jdermsci.2018.06.009 0 1 0 118 Humans|*Methotrexate|*Psoriasis|Dermatologic Agents|*Genetic Polymorphism|Severity of Illness Index|Treatment Outcome|*Chinese 66 UPK1A 30060568 Molecules 2018 PMC6222628 10.3390/molecules23081890 0 0 0 118 *Dendrimers|*Onions|Adhesins, Escherichia coli|Fimbriae Proteins|Fimbriae, Bacterial|Mannopyranoside|Bacterial Adhesion|*Glycosylation|Escherichia coli 66 UPK1A 29621584 J Ethnopharmacol 2018 10.1016/j.jep.2018.04.003 1 0 0 118 *Amaranthus|*Urothelium|E coli Infection|Uropathogenic Escherichia coli|Urinary Tract Infections|Bacterial Adhesion|Biofilms|Epithelial Cells|Urinary Bladder|Plant Extracts|Anti-Bacterial Agents|Cell Line 66 UPK1A 29325696 Nephrol. Ther. 2018 10.1016/j.nephro.2017.09.002 1 0 0 118 Humans|*Kidney Transplantation|*Epithelial-Mesenchymal Transition|*mRNA|Prospective Studies|*Kidney|*Transplantation, Homologous|Graft Rejection|*Biomarkers|*Urinalysis|Biopsy|Fibrosis|Vimentin|ROC Curve|PTPRC protein, human|Leukocyte Common Antigens 66 UPK2 30061246 Anticancer Res. 2018 10.21873/anticanres.12784 0 0 0 81 Humans|Male|*Uroplakin II|prostein|*Neoplasms, Unknown Primary|*Membrane Proteins|Immunohistochemistry|Carcinoma, Transitional Cell|Urinary Bladder Neoplasms|Urothelium|Tissue Array Analysis|Biomarkers, Tumor|Adenocarcinoma|Prostatic Neoplasms|Diagnosis, Differential|SATB2 protein, human|Transcription Factors|Matrix Attachment Region Binding Proteins 124 UPK2 29688031 Arch. Pathol. Lab. Med. 2018 10.5858/arpa.2017-0260-OA 0 0 0 81 Female|*Cystadenocarcinoma, Serous|GATA3 protein, human|GATA3 Transcription Factor|Uroplakin II|PAX8 Transcription Factor|Urothelium|Biomarkers, Tumor|Ascitic Fluid|Paired Box Transcription Factors|*Body Fluids|Diagnosis, Differential 124 UPK2 29465304 Am. J. Physiol. Renal Physiol. 2018 PMC6087793 10.1152/ajprenal.00075.2017 1 0 0 81 Humans|Mice|Animals|*Cystitis, Interstitial|*Urothelium|*Mice, Inbred C57BL|Upk2 protein, mouse|Uroplakin II|Bladder|Cystitis|Urination|*Tumor Necrosis Factor-alpha|Pelvic Pain|Transgenic Mouse|Tactile Allodynia|Disease Models, Animal|Mast Cell|mRNA 124 URAD 30380796 Int J Environ Res Public Health 2018 PMC6267203 10.3390/ijerph15112410 0 0 0 3 *Soils|*Arsenic|Ecosystem|*Heavy Metals|*Mining|Soil Pollutants|Mercury|*Risk Assessment|Environmental Monitoring|Zinc|Environmental Pollution|China 55 USP29 30343319 Cell. Mol. Life Sci. 2018 10.1007/s00018-018-2933-6 3 1 0 22 Humans|FUBP1 protein, human|RNA Binding Protein|DNA Helicases|Proto-Oncogene Proteins c-myc|Carcinogenesis|Cell Proliferation|Cell Line, Tumor|Cell Transformation, Neoplastic|Hematopoiesis 34 USP29 30335829 PLoS ONE 2018 PMC6193732 10.1371/journal.pone.0206112 2 0 0 22 *Alleles|Genomic Imprinting|*Mutations|Kruppel-Like Transcription Factors|DNA Methylation|Nerve Tissue Proteins|Carrier Proteins|Ubiquitin-Specific Proteases|Binding Sites 34 USP29 30308275 Int J Pharm 2018 10.1016/j.ijpharm.2018.10.014 0 0 0 22 *Tablets|Excipients|Tensile Strength|Pharmaceutical Formulation|*Pressure|microcrystalline cellulose|Cellulose|Technology, Pharmaceutical|Chemistry, Pharmaceutical|Hardness|Test, Hardness|*Physical Phenomena|*Data Compression|*Mechanical Phenomena|Models, Chemical 34 USP29 29734399 PLoS ONE 2018 PMC5937776 10.1371/journal.pone.0197069 5 0 0 22 Male|Female|Animals|Mice|*Alleles|Genomic Imprinting|Kruppel-Like Transcription Factors|DNA Methylation|Phenotypes|Ubiquitin-Specific Proteases|Nerve Tissue Proteins|Protein Domains|Mutation|Gene Dosage|Peg3 protein, mouse 34 UTF1 30446626 Development 2018 10.1242/dev.164160 1 7 0 98 Mice|Animals|*Germ Cells|*Signal Transduction|Epiblast|Bone Morphogenetic Protein 4|Gene Expression Regulation, Developmental|SETDB1 protein, human|*Protein Methyltransferases|Positive Regulatory Domain I-Binding Factor 1|Mesoderm|Cell Differentiation|Transcription Factors|Epigenesis, Genetic|SETDB1 protein, mouse|Histone-Lysine N-Methyltransferase 110 UTF1 30396549 Fertil. Steril. 2018 10.1016/j.fertnstert.2018.07.018 3 3 0 98 Male|Humans|*Temperature|Spermatogonia|Testis|Sertoli Cells|Spermatogenesis|Leydig Cells|*Gonadotropin|Fertility Preservation|Cryopreservation|Cell Proliferation|Dietary Supplements 110 UTF1 30048506 PLoS ONE 2018 PMC6062072 10.1371/journal.pone.0201239 0 39 0 98 Humans|Mice|Animals|*Human Induced Pluripotent Stem Cells|*Feeder Cells|*Endoderm|*Cell Differentiation|Pluripotent Stem Cells|Embryonic Stem Cells|Cell Culture Techniques|Octamer Transcription Factor-3|Coculture Techniques|Cells, Cultured|Fibroblasts|Embryo, Mammalian|*B Cells|Genes, Homeobox 110 UTF1 29934815 Genes Genomics 2018 10.1007/s13258-018-0690-4 4 7 0 98 Male|Mice|Animals|*Spermatocytes|*RNA, Long Noncoding|*mRNA|Spermatogenesis|Spermatogonia|Spermatid|Testis|Cellular Proliferation|Cell Differentiation|Gene Expression Regulation, Developmental|Utf1 protein, mouse|Chromosomal Proteins, Non-Histone|Trans-Activators 110 UTF1 29845790 Cell J 2018 PMC6004995 10.22074/cellj.2018.5482 1 3 0 98 Mice|Animals|*DNA Methylation|*Embryonic Stem Cell|Blastocyst Inner Cell Mass|Pluripotent Stem Cells|Mouse Embryonic Stem Cells|Cell Differentiation|*Gene Expression|Octamer Transcription Factor-3|Embryo Culture Techniques|Embryo, Mammalian|PD 0325901|Benzamides|Transforming Growth Factor beta|4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide|Mitogen-Activated Protein Kinase Kinases|Diphenylamine|Dioxoles 110 UTF1 29487166 Biochem. J. 2018 PMC5896025 10.1042/BCJ20170418 5 2 0 98 SOX2 protein, human|*SOXB1 Transcription Factors|POU5F1 protein, human|Octamer Transcription Factor-3|*Cell Differentiation|Endoderm|Cell Lineage|Blastocyst|Nanog Homeobox Protein|Embryonic Stem Cells|Homeodomain Proteins|Embryo, Mammalian|Gene Expression Regulation, Developmental 110 UTF1 29362495 Sci Rep 2018 PMC5780389 10.1038/s41598-018-20336-x 0 0 0 98 *Inheritance|*Heredity|*Epigenetic|*Databases, Genetic|Epigenesis, Genetic 110 VAX2 30116102 Evol. Bioinform. Online 2018 PMC6088467 10.1177/1176934318790266 2 0 0 24 Humans|Oligonucleotide Array Sequence Analysis|Artificial Intelligence|Gene Expression Profiling|*Cancer Survivors|Databases, Genetic|Computational Biology|Algorithms|Model, Computer|Machine Learning|Genetic Markers 164 VAX2 29947570 Ophthalmic Genet. 2018 10.1080/13816810.2018.1484927 0 0 0 24 *Cone Dystrophy|Retinal Degeneration|Electroretinography|DNA Mutational Analysis|Pedigree|Mutation|Phenotype|Tomography, Optical Coherence|Polymerase Chain Reaction 164 VIPAS39 29778605 J. Mol. Biol. 2018 PMC6005816 10.1016/j.jmb.2018.05.019 4 18 0 57 Humans|*Proteomics|Endosome|Vesicular Transport Proteins|Protein Transport|Vacuole|Membrane Fusion|*Cell Interaction|VPS33A protein, human|VPS33B protein, human|NRBF2 protein, human|Trans-Activators|CCDC22 protein, human|Proteins 24 VIPAS39 29729199 Hepatology 2018 10.1002/hep.30077 2 1 0 57 Humans|Male|Mice|Animals|Carcinoma, Hepatocellular|Liver Cancer|Hepatocytes|*Genes, Tumor Suppressor|Diethylnitrosamine|*Protein Transport|CDH1 protein, human|E Cadherin|flotillins|Membrane Proteins|Liver|Hep G2 Cells|Cell Movement|Vesicular Transport Proteins|*Carcinogenesis|Mice, Knockout|Signal Transduction|Hepatitis 24 VIPAS39 29409756 Biochim Biophys Acta Mol Basis Dis 2018 PMC5906731 10.1016/j.bbadis.2018.01.028 6 0 0 57 Humans|Mice|Animals|Arthrogryposis renal dysfunction cholestasis syndrome|Arthrogryposis|Cholestasis|Renal Insufficiency|Vesicular Transport Proteins|Phenotype|Mutations|Ichthyoses|Cell Polarity|*Secretory Vesicles|Lysosome|VPS33B protein, human|VPS33B protein, mouse 24 VSX1 30574758 J. 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Genet. 2018 10.1038/s10038-018-0504-1 1 0 0 45 Humans|*Anophthalmos|*Microphthalmos|*Phenotype|Eye Abnormalities|Exome|*Sequencing, Next-Generation|Mutations|Eye|Eye Proteins|SOXB1 Transcription Factors 115 VSX1 30090183 J Ophthalmic Vis Res 2018 PMC6058540 10.4103/jovr.jovr_116_17 1 1 0 45 *Keratoconus|Eye Proteins|Homeodomain Proteins|Pedigree|Mutation|Brazil 115 VSX1 29924831 PLoS ONE 2018 PMC6010250 10.1371/journal.pone.0199178 3 0 0 45 Humans|*Keratoconus|Australia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Cohort Studies|Eye Proteins|Base Sequence|Homeodomain Proteins|*Continental Population Groups|SLC4A11 protein, human|Antiporters|Anion Transport Proteins 115 VSX1 29651232 Front Neurosci 2018 PMC5884927 10.3389/fnins.2018.00170 4 3 0 45 Animals|Mice|GATA3 protein, human|*GATA3 Transcription Factor|Zebrafish|TAL1 protein, human|*T-Cell Acute Lymphocytic Leukemia Protein 1|Spinal Cord|Zebrafish Proteins|Interneurons|Motor Neurons|Cell Differentiation|Gene Expression Regulation, Developmental|Cell Lineage|GATA2 Transcription Factor|Signal Transduction 115 VSX1 29518881 Zhonghua Yan Ke Za Zhi 2018 10.3760/cma.j.issn.0412-4081.2018.03.012 2 0 0 45 115 VTCN1 30564631 NPJ Breast Cancer 2018 PMC6288133 10.1038/s41523-018-0095-1 3 1 0 317 Humans|CD274 protein, human|*B7-H1 Antigen|*Lymphocytes, Tumor-Infiltrating|VTCN1 protein, human|V-Set Domain-Containing T-Cell Activation Inhibitor 1|Prognosis|Triple-Negative Breast Cancers|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 232 VTCN1 30486739 Tumour Biol. 2018 10.1177/1010428318815032 1 1 0 317 Humans|*Tumors, Phyllodes|*Immunohistochemistry|*RNA|*T-Lymphocytes|Neoplasm Recurrence, Local|Molecules, B7|*In Situ Hybridization|V-Set Domain-Containing T-Cell Activation Inhibitor 1|Lymphocytes, Tumor-Infiltrating|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease Progression|Breast Neoplasms 232 WDFY4 30559488 Nat. Genet. 2018 PMC6309590 10.1038/s41588-018-0288-4 20 0 0 12 Child|Humans|*DNA Copy Number Variations|*Neurodevelopmental Disorders|Developmental Disabilities|Intellectual Disability|Exome|Autism|Mutation|Phenotype 20 WDFY4 30409884 Science 2018 PMC6655551 10.1126/science.aat5030 22 0 0 12 Mice|Animals|*Cross-Priming|*Tumor Antigens|CD8 Antigens|Basic-Leucine Zipper Transcription Factors|Dendritic Cells|CD8-Positive T-Lymphocytes|Repressor Proteins|Mice, Inbred C57BL 20 WDFY4 30257884 J. Immunol. 2018 10.4049/jimmunol.1800399 0 3 0 12 Genome-Wide Association Study|*Lupus Erythematosus, Systemic|*B-Lymphocytes|*Autophagy|Intracellular Signaling Peptides and Proteins|Autoantibodies 20 WDFY4 29331962 Ann. Rheum. Dis. 2018 10.1136/annrheumdis-2017-212149 4 4 0 12 Humans|Genome-Wide Association Study|Amyopathic dermatomyositis|Dermatomyositis|Polymyositis|Interferon-Induced Helicase, IFIH1|Idiopathic Inflammatory Myopathies|Asian|Autoantibodies|Case-Control Studies|*RNA Splicing 20 WFDC1 30423385 Gene 2018 10.1016/j.gene.2018.10.046 1 0 0 69 Humans|Male|Animals|*Prostate|*Phylogeny|Bayes Theorem|WFDC1 protein, human|*Proteins|*Evolution, Molecular|Prostate Cancer|Exons|Syntenic Conservation|Vertebrate 42 WFDC1 29548303 Genome Biol. 2018 PMC5857099 10.1186/s13059-018-1412-6 8 21 0 69 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*RNA Binding Protein|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|RNA, Messenger|Disease Progression|SORBS2 protein, human|Homeodomain Proteins 42 WHAMM 30420355 J. Cell Biol. 2018 PMC6314544 10.1083/jcb.201802157 6 44 0 1784 *Autophagosomes|*Actin Filament|Arp2-3 Complex|Actin|Trans-Activators|Autophagy|Microtubule-Associated Proteins|Nuclear Proteins|Cell Nucleus|Cytoplasm|Cytosol|Cell Membrane|*Macroautophagy 33 WISP2 30531839 Oncogene 2018 PMC6450751 10.1038/s41388-018-0610-8 5 6 0 13 Animals|Mice|LATS1 protein, human|*Protein-Serine-Threonine Kinases|Transcription Factors|Phosphoproteins|Adaptor Proteins, Signal Transducing|Cell Cycle Proteins|Signal Transduction|Tumor Suppressor Proteins|*Cell Transformation, Neoplastic|Cell Proliferation|CCN5 protein, human|Repressor Proteins|*B-Lymphocytes|Tumorigenesis|Cell Line, Tumor|Homeostasis|CCN Intercellular Signaling Proteins|Ccdc80 protein, mouse 117 WISP2 30393824 J Cell Commun Signal 2018 PMC6235780 10.1007/s12079-018-0491-1 16 0 0 13 CCN4 protein, human|*CCN Intercellular Signaling Proteins|*Proto-Oncogene Proteins|Nephroblastoma Overexpressed Protein|Connective Tissue Growth Factor|Cysteine-Rich Protein 61|Immediate-Early Proteins|Signal Transduction|RNA, Messenger 117 WISP2 30153702 Int. 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Res. 2018 10.1055/a-0593-5956 1 0 0 13 117 WISP2 29455304 J Cell Commun Signal 2018 PMC5842214 10.1007/s12079-018-0463-5 0 0 0 13 Mice|Animals|*Mice, Knockout|CCN5 protein, human|*CCN Intercellular Signaling Proteins|*Repressor Proteins|Intracellular Signaling Peptides and Proteins 117 WISP2 29396648 J Cell Commun Signal 2018 PMC5842209 10.1007/s12079-018-0457-3 0 1 0 13 Mice|Animals|*Mice, Knockout|CCN5 protein, human|CCN Intercellular Signaling Proteins|Cell Differentiation|Repressor Proteins|Cell Proliferation|Intracellular Signaling Peptides and Proteins|*Bone 117 XIRP2 30515977 Mol Nutr Food Res 2018 10.1002/mnfr.201800970 2 0 0 38 Mice|Animals|*DNA Methylation|*Obesity|Epigenesis, Genetic|Diet, High-Fat|*Epigenetic|Disease Models, Animal|Cardiomyopathies|Dietary Fats 42 XIRP2 30410445 Front Physiol 2018 PMC6210548 10.3389/fphys.2018.01442 3 0 0 38 42 XIRP2 30152531 Anim. Genet. 2018 10.1111/age.12715 0 0 0 38 Horses|Animals|Poland|*Osteochondrosis|*Breeding|Horse Diseases|Hock|Genotype|SNPs|Quantitative Trait Loci|*Genetic Selection|Phenotype|Microsatellite Repeats|*Sport 42 XIRP2 29874122 Mol. Biol. Cell 2018 PMC6085822 10.1091/mbc.E18-03-0196 2 7 0 38 Mice|Animals|*Stereocilia|*Actins|fascin|Actin Binding Proteins|FSCN1 protein, human|Carrier Proteins|Hair Cells, Auditory|Filaments, Actin|Morphogenesis|Ear|*Longitudinal Studies 42 XIRP2 29650764 Circ Genom Precis Med 2018 PMC5901893 10.1161/CIRCGEN.117.001854 2 1 0 38 Humans|*Antihypertensive Agents|*Renin|*Pharmacogenetics|Genome-Wide Association Study|*Hypertension|Blood Pressure|Hydrochlorothiazide|Atenolol|Single Nucleotide Polymorphisms|European Continental Ancestry Group 42 XIRP2 29570242 Birth Defects Res 2018 PMC5903934 10.1002/bdr2.1223 0 0 0 38 Infant, Newborn|Humans|*Hernias, Diaphragmatic, Congenital|Diaphragm|COUP Transcription Factor II|*Germ Line|*Diploidy|Mutation 42 XIRP2 29306897 J Am Heart Assoc 2018 PMC5778954 10.1161/JAHA.117.006320 1 8 0 38 Humans|Mice|Animals|*Brugada Syndrome|NAV1.5 Voltage-Gated Sodium Channel|*Asian Continental Ancestry Group|Gene Frequency|Genetic Predisposition to Disease|Mutations|Genotype|Death, Sudden|Ethnic Groups|Myocardium|Arrythmia 42 XPO4 30516367 ACS Appl Mater Interfaces 2018 10.1021/acsami.8b18930 0 0 0 139 Lithium|Electric Power Supplies|Electrodes|Oxides|Manganese|Nanostructures|Surface Properties|Particle Size 35 XPO4 29911701 Phys Chem Chem Phys 2018 10.1039/c8cp01949e 0 0 0 139 LiFePO4|*Lithium|Electric Power Supplies|Cathode|*Ions|olivine|Iron Compounds|Magnesium Compounds|Iron|Phosphate|Electrochemistry|Silicates|Diffusion 35 XPO4 29762025 Inorg Chem 2018 10.1021/acs.inorgchem.8b00095 3 0 0 139 *Spectroscopy|Curium|Actinoid Series Elements|Water 35 XPO4 29309122 ACS Appl Mater Interfaces 2018 10.1021/acsami.7b14552 0 0 0 139 *Electrodes|Electric Capacitance|potassium phosphate|*Phosphates|*Potassium Compounds|Cobalt|Nickel|Potassium 35 Y_RNA 30517885 Structure 2018 10.1016/j.str.2018.11.009 0 0 0 0 *tRNA|Nucleic Acid Conformation|RNA, Bacterial|Ribosomes|Base Pairing|Binding Sites|Molecular Mimicry|Models, Molecular|Crystallography, X-Ray 117 Y_RNA 30380423 Cell Rep 2018 PMC6261476 10.1016/j.celrep.2018.10.014 16 1 0 0 Humans|Sequencing, RNA|MicroRNAs|piRNA|tRNA|High-Throughput Nucleotide Sequencing|Base Sequence|Biomarkers|Serum|*Diagnostic Tests, Routine|Plasma 117 Y_RNA 30318468 Structure 2018 PMC6281776 10.1016/j.str.2018.09.001 2 0 0 0 Animals|*tRNA|Anticodon|Nucleic Acid Conformation|RNA, Bacterial|Base Sequence|*Bacteria|Models, Molecular 117 Y_RNA 30175283 Noncoding RNA Res 2018 PMC6114264 10.1016/j.ncrna.2018.04.005 1 0 0 0 *Non-Coding RNA|RNA|Nucleic Acid Conformation|Base Sequence|Algorithms|Thermodynamics 117 Y_RNA 30029004 Mol. Cell 2018 PMC6060611 10.1016/j.molcel.2018.06.032 9 27 0 0 *mTORC1|ELAV-Like Protein 4|3' UTR|mRNA|Axons|RNA Binding Protein|Neurogenesis|Motor Neurons|*Regulatory Sequences, Nucleic Acid|RNA, Small Untranslated 117 Y_RNA 30006996 Microbiol Spectr 2018 PMC6047535 10.1128/microbiolspec.RWR-0023-2018 7 0 0 0 Humans|Animals|*tRNA|Noncoding RNA|RNA, Small Cytoplasmic|Ribonucleoproteins|Nucleic Acid Conformation|RNA, Bacterial|Autoantigens|Autoantibodies 117 Y_RNA 29866742 Hypertension 2018 PMC6043385 10.1161/HYPERTENSIONAHA.118.11239 6 2 0 0 Mice|Humans|Animals|*Angiotensin II|*Exosomes|Cardiac Hypertrophy|Blood Pressure|Hypertension|Myocardium|Myocytes, Cardiac|Fibrosis|IL10 protein, human|Interleukin-10|Myocardial Infarction|Echocardiography|Kidney|Disease Models, Animal|RNA 117 YBEY 29914987 J. 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Biol. 2018 10.1016/j.jmb.2018.04.009 12 0 0 103 *Escherichia coli|*RNA, Ribosomal, 16S|ribonuclease R|Exoribonucleases|ribonuclease PH|Escherichia coli Proteins|Ribosomes|exoribonuclease II|RNA, Bacterial|Ribosomal Proteins|RNA Processing, Post-Transcriptional|Metalloproteins|RNA, Ribosomal|YbeY protein, E coli 37 YBEY 29632093 J. Bacteriol. 2018 PMC5971472 10.1128/JB.00105-18 1 0 0 103 Mice|Animals|*Brucella abortus|*Virulence|Brucellosis|*Endoribonucleases|Gene Expression Regulation, Bacterial|Virulence Factors|Mice, Inbred BALB C|Bacterial Proteins 37 YBEY 29572226 Cancer Res. 2018 10.1158/0008-5472.CAN-17-1721 2 0 0 103 Humans|Female|*Exome|Genome-Wide Association Study|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies 37 YBX2 30295753 Biol. Reprod. 2018 10.1093/biolre/ioy213 0 3 0 47 Humans|Male|Mice|Animals|*mRNA|*Spermiogenesis|Spermatids|RNA-Binding Proteins|Testes|RNA|Protein Binding|HeLa Cells|YBX2 protein, human|Ybx2 protein, mouse 92 YBX2 30129372 Syst Biol Reprod Med 2018 10.1080/19396368.2018.1505973 0 0 0 47 Male|Mice|Animals|protamine 2|*Protamines|Spermatogenesis|*Gene Expression|Testis|Spermatozoa|mRNA|Histones|*Germ Cells 92 YBX2 29738886 Comp. Biochem. Physiol. Part D Genomics Proteomics 2018 10.1016/j.cbd.2018.04.006 0 0 0 47 Female|Animals|*Ovary|*Proteomics|*Vitellogenesis|*Fishes|Vitellogenin|Oestradiol|Testosterone|Sexual Maturation|Aquiculture|Two Dimensional Gel Electrophoresis 92 YBX2 29650336 J Sci Med Sport 2018 10.1016/j.jsams.2018.01.013 2 0 0 47 Humans|*Hemodynamics|Resistance Training|Oxygen Consumption|Heart Rate|Regional Blood Flow|Blood Pressure|Adaptation, Physiological 92 ZBED3 30417576 J. Cell. Mol. Med. 2018 PMC6349170 10.1111/jcmm.14001 1 8 0 98 *Glycogen Synthase Kinase 3|Carcinoma, Non-Small-Cell Lung|*Axin Protein|Lung Cancer|beta Catenin|A549 Cells|CCND1 protein, human|Cyclin D1|Cell Proliferation|Wnt Signaling Pathway|Catenins|Downregulation|Cell Line, Tumor 21 ZBED3 29749482 Int. J. Oncol. 2018 10.3892/ijo.2018.4403 5 0 0 98 Humans|Female|*Long Non-Coding RNA|*Platinum|*Drug Resistance, Neoplasm|*Carcinoma, Ovarian Epithelial|*Prognosis|*Ovarian Cancer|Cystadenocarcinoma, Serous|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Biomarkers, Tumor|Kaplan-Meier Estimate|RNA, Messenger|Disease-Free Survival|Upregulation|Antineoplastic Agents|ZBED3 protein, human|DNA-Binding Proteins 21 ZBED3 29535782 Stem Cells Int 2018 PMC5829309 10.1155/2018/8273648 15 64 0 98 *RNA, Long Noncoding|*Mesenchymal Stem Cells|Cell Differentiation|Osteogenesis|Osteoblasts|*Bone Regeneration|Stem Cells 21 ZBTB18 30410579 Mol Cytogenet 2018 PMC6219057 10.1186/s13039-018-0406-0 0 1 0 323 Humans|*Phenotype|Microcephaly|Chromosome Deletion|Agenesis of Corpus Callosum|Intellectual Disability|Seizures|Syndrome|*Chromosome Structures 41 ZBTB18 30392794 Neuron 2018 PMC6428593 10.1016/j.neuron.2018.10.016 6 6 0 323 Nerve Tissue Proteins|*Neocortex|Receptors, Immunologic|Corpus Callosum|Agenesis, Corpus Callosum|Axons|Pyramidal Neurons|Neurons|Neurogenesis|Interneurons|Cell Movement|Gene Expression Regulation, Developmental|Forkhead Transcription Factors|Nervous System Malformations 41 ZBTB18 29573576 Mol Genet Genomic Med 2018 PMC6014478 10.1002/mgg3.387 1 0 0 323 Child|Humans|Intellectual Disability|Microcephaly|Hypotonia|Developmental Disabilities|Chromosome Deletion|Exome|Mutation 41 ZBTB18 29501651 Brain Res. 2018 10.1016/j.brainres.2018.02.042 1 1 0 323 Animals|Mice|Neurogenesis|*Transcription Factors|Cell Movement|Progenitor Cells|Neurons|Repressor Proteins|Cell Differentiation|Hippocampus|Neocortex|Gene Expression Regulation, Developmental|Cell Cycle|Embryogenesis|Cell Division|*Nervous System Physiological Phenomena 41 ZBTB18 29344557 Oncoscience 2018 PMC5769983 10.18632/oncoscience.386 0 2 0 323 DNA, Mitochondrial|Mitochondria|*Colon|Cell Line, Tumor 41 ZBTB38 30569128 Oncol. Rep. 2018 10.3892/or.2018.6937 4 2 0 165 Humans|*Urinary Bladder Neoplasms|*Bladder|Cell Proliferation|Neoplasm Invasiveness|Cell Movement|Wnt Signaling Pathway|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|beta Catenin|Cell Line, Tumor|Down-Regulation|RNA, Small Interfering|Xenograft Model Antitumor Assays|ZBTB38 protein, human|Repressor Proteins 43 ZBTB38 30480223 Epigenet Insights 2018 PMC6243405 10.1177/2516865718811117 1 0 0 165 Animals|*Chromatin|*DNA Methylation|*B-DNA|CpG Islands|Transcription Factors|DNA|DNA-Binding Proteins|Promoter Regions, Genetic|Repressor Proteins|Gene Expression Regulation|Protein Binding 43 ZBTB38 30355731 J. Biol. Chem. 2018 PMC6314133 10.1074/jbc.RA118.005147 4 1 0 165 *Methylations, DNA|*Zinc Fingers|CpG Islands|Protein Binding|DNA-Binding Proteins|Transcription Factors|Repressor Proteins|DNA|Amino Acid Sequence|Models, Molecular|Crystallography, X-Ray 43 ZBTB38 30343694 Biochim Biophys Acta Gene Regul Mech 2018 10.1016/j.bbagrm.2018.09.007 1 1 0 165 Mice|Animals|*Disease Models, Animal|*Rheumatoid Arthritis|DNA Methylation|*Downregulation|Promoter Regions, Genetic|Receptors, Interleukin-1 Type II|Gene Expression|*Anti-Inflammatory Agents|*Complement Factor B|3'-(1-butylphosphoryl)adenosine|B Cells|Transcription Factors 43 ZBTB38 30310057 Oncogenesis 2018 PMC6182000 10.1038/s41389-018-0092-0 3 1 0 165 Humans|*mRNA|*Up-Regulation|5 Azacytidine|Myelodysplastic Syndromes|Decitabine|CDKN1C protein, human|*Cyclin-Dependent Kinase Inhibitor p57|Leukemia, Myeloid, Acute|pyrimidin-2-one beta-ribofuranoside|Cytidine|Antimetabolites, Antineoplastic|Histone Deacetylase Inhibitors|Cell Line, Tumor|DNA Methylation|*DNA|ZBTB38 protein, human|Repressor Proteins 43 ZBTB38 30075197 Gene 2018 10.1016/j.gene.2018.07.073 2 2 0 165 Humans|*Autophagy|Autophagy-Related Proteins|Signal Transduction|*Injury, Spinal Cord|Intracellular Signaling Peptides and Proteins|Protein-Tyrosine Kinases|Gene Expression Regulation|*Cell Cycle Proteins|Gene Knockdown Techniques|Apoptosis|Cell Line|Transcriptome|RB1CC1 protein, human|ZBTB38 protein, human|Repressor Proteins 43 ZBTB38 29490077 Nucleic Acids Res. 2018 PMC5961141 10.1093/nar/gky149 8 25 0 165 Animals|Humans|*Oxidative Stress|Ubiquitin Thiolesterase|Ubiquitination|Ubiquitin|Apoptosis|Cell Line, Tumor|Reactive Oxygen Species|USP9X protein, human|ZBTB38 protein, human|Repressor Proteins 43 ZC3H12D 29875652 Front Aging Neurosci 2018 PMC5974056 10.3389/fnagi.2018.00143 3 21 0 498 *DNA Methylation|Leukoaraiosis|*Inflammation|White Matter|Disease Progression 20 ZC3H12D 29784731 Cancer Epidemiol. Biomarkers Prev. 2018 10.1158/1055-9965.EPI-17-0762 0 1 0 498 20 ZC3H13 30548174 Mol Oncol 2018 PMC6360371 10.1002/1878-0261.12423 0 6 0 158 Humans|Male|Myeloid-Lymphoid Leukemia Protein|Histone-Lysine N-Methyltransferase|Leukemia|Oncogene Proteins, Fusion|*Chromosomal Instability|Tumorigenesis 22 ZC3H13 30311220 J. Cell. Physiol. 2018 10.1002/jcp.27551 7 2 0 158 *Colorectal Cancer|*Signal Transduction|*Colonic Neoplasms|CCNE1 protein, human|Cyclin E|Extracellular Signal-Regulated MAP Kinases|Oncogene Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|CCND1 protein, human|Cyclin D1|MAP Kinase Signaling System|Genes, Tumor Suppressor 22 ZC3H13 29555755 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC5889661 10.1073/pnas.1720945115 17 0 0 158 22 ZC3H13 29547716 Mol. Cell 2018 PMC5858226 10.1016/j.molcel.2018.02.015 71 5 0 158 *RNA, Nuclear|Nuclear Proteins|RNA, Messenger|Methyltransferases|Methylation|Adenosine|Cell Differentiation 22 ZC3H13 29535189 Genes Dev. 2018 PMC5900714 10.1101/gad.309146.117 52 0 0 158 22 ZC3H13 29507755 Cell Discov 2018 PMC5826926 10.1038/s41421-018-0019-0 68 10 0 158 22 ZC3H14 30578643 Protein Sci. 2018 PMC6371209 10.1002/pro.3565 0 1 0 116 Humans|polyadenosine|*RNA Binding Protein|*Adenosine|Saccharomyces cerevisiae|Nucleocytoplasmic Transport Proteins|*Polymers|Saccharomyces cerevisiae Proteins|Export, Nuclear|mRNA|Polyadenylation|RNA|Nuclear Pore Complex Proteins|Cell Nucleus|Protein Binding|Zinc Fingers|Structure-Activity Relationship|Zinc|NAB2 protein, human 23 ZC3H14 30371740 Carcinogenesis 2018 10.1093/carcin/bgy146 0 1 0 116 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Down-Regulation|*Liver Neoplasms|*Signal Transduction|*Disease Progression|Genes, Tumor Suppressor|Cell Line, Tumor|Cell Proliferation|Mice, Nude|Chromosome 14q, partial deletions|*Chromosome Deletion|Heterografts|*Chromosomes, Human, Pair 14|Integrins|ZC3H14 protein, human|Nuclear Proteins|RNA-Binding Proteins 23 ZC3H14 29912477 Nucleic Acids Res. 2018 PMC6061872 10.1093/nar/gky446 1 26 0 116 polyadenosine|*RNA Binding Protein|*Adenosine|*Cell Nucleus|*Polymers|Nuclear Proteins|RNA Precursors|*Neurons|RNA, Messenger|Drosophila Proteins|Cytoplasm|RNA|Transcription Factors|Conserved Sequence 23 ZC3H14 29627306 Toxicol. Lett. 2018 10.1016/j.toxlet.2018.04.002 3 3 0 116 Mice|Animals|*Paraquat|NFE2L2 protein, human|*NF-E2-Related Factor 2|*RNA, Long Noncoding|*1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|*Substantia Nigra|MPTP Poisoning|Herbicides|Dopaminergic Neurons|Corpus Striatum|Dopamine|Parkinson Disease|Mice, Inbred C57BL|Oxidative Stress|Neurodegenerative Diseases 23 ZDHHC9 30402882 Ann. Hum. Genet. 2018 10.1111/ahg.12294 1 0 0 61 Child|Humans|*Intellectual Disability|*Genetic Testing|Developmental Disabilities|Chromosomes|DNA Copy Number Variations|Sequencing, Next-Generation|*Nervous System Malformations|FMR1 protein, human|Fragile X Mental Retardation Protein|ZDHHC9 protein, human|Acyltransferases 30 ZDHHC9 29944857 Exp. Neurol. 2018 PMC6104741 10.1016/j.expneurol.2018.06.014 2 0 0 61 Humans|Male|Animals|Mice|*Intellectual Disability|*Mice, Inbred C57BL|Memory|*Disease Models, Animal|Brain|Morris Water Maze Test|*Problem Behavior|Learning, Spatial|Imaging, Magnetic Resonance|Corpus Callosum|Language Disorders|Mutations|Hippocampus|ZDHHC9 protein, human|Acyltransferases 30 ZDHHC9 29681091 Am. J. Med. Genet. 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Genet. 2018 PMC6189113 10.1038/s41431-018-0201-8 1 0 0 28 Humans|Genome-Wide Association Study|Single Nucleotide Polymorphism|Genotype|*Genomics|Shortterm Memory|Cohort Studies 70 zfhx4 30546116 Cancer Gene Ther. 2018 10.1038/s41417-018-0066-6 0 4 0 66 Humans|Mice|Female|Animals|*RNA, Long Noncoding|Mice, Nude|*Downregulation|*Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Movement|Cell Line, Tumor|Cell Cycle|Tumorigenesis|Disease Progression|*Neoplastic Processes|Cell Transformation, Neoplastic|FAT4 protein, human|Cadherins|Tumor Suppressor Proteins|Hippo protein, human 26 zfhx4 30391781 Cancer Lett. 2018 10.1016/j.canlet.2018.10.035 0 0 0 66 Humans|Genome Editing|CRISPR|CRISPR-Associated Protein 9|CRISPR-Cas Systems|RNA, Guide|Genome|*Chromosome Mapping|*Signal Transduction|Lung Neoplasms|Epithelial Cells|Genomics|RIT1 protein, human|ras Proteins 26 zfhx4 30075702 BMC Genomics 2018 PMC6090856 10.1186/s12864-018-4958-5 3 0 0 66 Humans|Animals|*Prognosis|*Antigens, Neoplasm|*Lung Adenocarcinoma|*Genes, MHC Class II|*DNA Mutational Analysis|Immunotherapy|Histocompatibility Antigens Class II|Epitopes, T-Lymphocyte|Peptides|T Cells|Mutation|Lung Neoplasms|Biomarkers 26 zfhx4 29463886 Mol. Psychiatry 2018 PMC6756287 10.1038/s41380-018-0020-x 16 0 0 66 Humans|Child|*Speech|Apraxia|Language Disorders|Speech Disorders|*Regulatory Genes|Mutations|Base Sequence|*Nervous System Physiological Phenomena|Forkhead Transcription Factors|Brain|MKL2 protein, human|KAT6A protein, human|Histone Acetyltransferases|WDR5 protein, human|Histone-Lysine N-Methyltransferase|Setd1A protein, human|TNRC6B protein, human|RNA-Binding Proteins 26 ZFP36L2 30574470 J Bone Metab 2018 PMC6288606 10.11005/jbm.2018.25.4.251 2 0 0 866 *Bayes Theorem|*Bone Neoplasms|Gene Regulatory Networks|Algorithms|Machine Learning|*Osteoblasts 71 ZFP36L2 30526691 Skelet Muscle 2018 PMC6286576 10.1186/s13395-018-0183-9 1 0 0 866 *Muscle Development|*RNA-Binding Proteins|Satellite Cells, Skeletal Muscle|PAX7 Transcription Factor|Tristetraprolin|mRNA Degradation|Nuclear Proteins|Regeneration|Cell Differentiation|3' UTR|Cell Proliferation|Muscle, Skeletal|Signal Transduction|mRNA 71 ZFP36L2 30478191 EMBO J. 2018 PMC6293276 10.15252/embj.201899333 9 1 0 866 Mice|Animals|*Oocyte|Oogenesis|Meiosis|mRNA deadenylase|Ribonucleases|Cell Cycle Proteins|Transcription Factors|RNA, Messenger|Transcription, Genetic|Gene Expression Regulation, Developmental 71 ZFP36L2 30421875 J Sports Med Phys Fitness 2018 10.23736/S0022-4707.18.09204-6 0 0 0 866 Animals|*Pulmonary Arterial Hypertension|Gene Ontology|*Familial Primary Pulmonary Hypertension|Gene Expression Profiling|Computational Biology|Gene Regulatory Networks|Transcriptome|Databases, Genetic|*Exercise Training 71 ZFP36L2 29988089 Nat. Immunol. 2018 PMC6643272 10.1038/s41590-018-0155-6 11 0 0 866 Humans|Mice|Animals|*mRNA|*Immunologic Memory|*T-Lymphocytes|AU Rich Elements|Tristetraprolin|3' Untranslated Region|RNA Stability|*Cytokines|Macrophages|Tumor Necrosis Factor-alpha|Cell Line 71 ZFP36L2 29555671 Circ Genom Precis Med 2018 10.1161/CIRCGEN.117.001978 12 0 0 866 *Exome|*Heart Defects, Congenital|Genetic Testing|Pedigree|Genetic Predisposition to Disease|Gene Frequency|High-Throughput Nucleotide Sequencing|Mutation 71 ZFP36L2 29518627 Leuk. Res. 2018 10.1016/j.leukres.2018.02.017 3 10 0 866 Humans|RUNX1 Translocation Partner 1 Protein|*Leukemia, Myeloid, Acute|Core Binding Factor Alpha 2 Subunit|*Cell Proliferation|*Apoptosis|Translocation, Genetic|Oncogene Proteins, Fusion|Cell Differentiation|Promoter Regions, Genetic|Transcriptional Activation|Cell Line, Tumor|Binding Sites|Histone Deacetylases|Histone Deacetylase Inhibitor 71 ZFP36L2 29449217 Biol Open 2018 PMC5898266 10.1242/bio.031575 3 15 0 866 Humans|*Protein A|RNA-Binding Proteins|Tristetraprolin|Rich Element, AU|DNA Replication|RNA, Messenger|Zinc Fingers|Ubiquitination|E3 Ligase|*Cell Cycle Control|*DNA|HEK293 Cells 71 ZFP36L2 29426877 Sci Rep 2018 PMC5807420 10.1038/s41598-018-21160-z 5 81 0 866 Humans|*Tumor Suppressor Protein p53|*Cyclin|*Cell Proliferation|Cyclin-Dependent Kinase Inhibitor p21|*Proliferating Cell Nuclear Antigen|Cell Cycle Proteins|Cell Cycle|HCT116 Cells|*Cell Cycle Checkpoints|Signal Transduction|Phosphorylation|Colonic Neoplasms|Cyclin D|ZFP36L1 protein, human|Butyrate Response Factor 1 71 ZFP36L2 29408237 Dev. Cell 2018 PMC5805474 10.1016/j.devcel.2018.01.006 6 15 0 866 Humans|Female|Mice|Animals|*Oocyte|Oogenesis|*mRNA Decay|mRNA|RNA Binding Protein|Gene Expression Regulation, Developmental|Female Infertility|Embryo, Mammalian|Methylation|Chromatin 71 ZFP36L2 29295643 Leuk. Lymphoma 2018 10.1080/10428194.2017.1413186 0 0 0 866 Humans|*Burkitt Lymphoma|Neoplasm Recurrence, Local|*Genome|*Genomics|Genes, myc|Mutations|Cyclin D3|Signal Transduction|*Relapse|Cell Line|SIRT4 protein, human|Mitochondrial Proteins|Sirtuins 71 ZHX2 30146259 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.08.088 0 0 0 190 Mice|Animals|*Transcription Factor|Amacrine Cells|*Cell Differentiation|Retina|Retinal Rod Photoreceptor Cells|Glia|Homeodomain Proteins|Gene Expression Regulation, Developmental|Retinal Ganglion Cells|Neurogenesis|Zhx2 protein, mouse 78 ZHX2 30026271 Arterioscler. Thromb. Vasc. Biol. 2018 PMC6202168 10.1161/ATVBAHA.118.311266 3 1 0 190 Mice|Animals|*Atherosclerosis|LDLR protein, human|Low Density Lipoprotein Receptor|*Apoptosis|Homeodomain Proteins|Mice, Knockout|Transcription Factor|Liver|Macrophages|Zhx2 protein, mouse 78 ZHX2 30026228 Science 2018 PMC6154478 10.1126/science.aap8411 13 11 0 190 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Von Hippel-Lindau Tumor Suppressor Protein|*Oncogenes|*Oncogenesis|Transcription Factors|Nuclear Proteins|Gene Expression Regulation, Neoplastic|*Complement Factor B|Mutation|Cell Line, Tumor|VHL protein, human|ZHX2 protein, human|Homeodomain Proteins 78 ZHX2 29752719 Int. J. Cancer 2018 10.1002/ijc.31595 9 1 0 190 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Hepatitis B virus|*Liver Neoplasms|Hepatitis B, Chronic|hepatitis B virus X protein|Trans-Activators|MicroRNAs|Hep G2 Cells|Gene Expression Regulation, Neoplastic|Cell Proliferation|Genes, Tumor Suppressor|RNA, Messenger|Oncogenesis|Livers|Cell Line, Tumor|ZHX2 protein, human|Transcription Factors|Homeodomain Proteins 78 ZHX2 29580980 Antiviral Res. 2018 10.1016/j.antiviral.2018.03.008 3 4 0 190 Animals|Mice|*B virus, Hepatitis|Epigenesis, Genetic|Circular DNA|Hepatitis B e Antigens|Virus Replication|DNA, Viral|Hepatitis B, Chronic|Gene Expression Regulation, Viral|Transcription, Genetic|Histone|Epigenetic Repression|RNA|Hepatocytes|Hep G2 Cells|Zhx2 protein, mouse|Homeodomain Proteins 78 ZIC4 30406191 eNeuro 2018 PMC6220585 10.1523/ENEURO.0367-18.2018 1 2 0 48 Male|Female|Mice|Animals|Paired Box Transcription Factors|Homeodomain Proteins|Repressor Proteins|Eye Proteins|PAX6 Transcription Factor|Gene Expression Regulation, Developmental|Hedgehog Proteins|Thalamus|Stem Cells|Embryogenesis 76 ZIC4 30391508 Eur J Med Genet 2018 10.1016/j.ejmg.2018.10.018 1 0 0 48 Child|Humans|*Microcephaly|*Scoliosis|*Agenesis of Corpus Callosum|*Nervous System Malformations|*Cerebellum|*Zinc Finger|Dandy-Walker Malformation|*Neural Tube Defect|Exome|TYRP1 protein, human|*Membrane Glycoproteins|Craniosynostosis|Transcription Factors|Developmental Disabilities|Mutation 76 ZIC4 30057463 Noro Psikiyatr Ars 2018 PMC6060648 10.29399/npa.23033 1 0 0 48 Humans|*Prognosis|Hashimoto's encephalitis|Encephalitis|Paraneoplastic Syndromes, Nervous System|Hashimoto Disease|*Neurons|Autoantibodies|*Complement Factor B|Nerve Tissue Proteins|3'-(1-butylphosphoryl)adenosine 76 ZIC4 29988590 FEBS Open Bio 2018 PMC6026698 10.1002/2211-5463.12433 7 7 0 48 *Carcinoma, Hepatocellular|*DNA Methylation|*Liver Neoplasms|CpG Islands|*Gene Expression|Cell Line, Tumor|*DNA 76 ZIC4 29628984 J Breast Cancer 2018 PMC5880966 10.4048/jbc.2018.21.1.51 2 11 0 48 Humans|*Prognosis|*Zinc Finger|Transcription Factors|*Cerebellum|Kaplan-Meier Estimate|Multigene Family|RNA, Messenger|Quantitative Real Time Polymerase Chain Reaction 76 ZIC4 29525731 Clin Neurol Neurosurg 2018 10.1016/j.clineuro.2018.02.043 1 0 0 48 Creutzfeldt-Jakob Disease, Sporadic|*Creutzfeldt-Jakob Syndrome|Hashimoto's encephalitis|Encephalitis|Hashimoto Disease|Myoclonus|*Neurons|Movement Disorders|Diagnosis, Differential|*Probability|Ataxia|Autoantibodies 76 ZIC4 29442326 Adv. Exp. Med. Biol. 2018 10.1007/978-981-10-7311-3_13 4 1 0 48 Humans|Mice|Animals|Hedgehog Proteins|*Cerebellum|Dandy-Walker Malformation|Zinc Finger|Homeodomain Proteins|Transcription Factors|Phenotypes|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Craniosynostoses|ZIC1 protein, human 76 ZIC4 29442321 Adv. Exp. Med. Biol. 2018 10.1007/978-981-10-7311-3_8 0 0 0 48 Animals|Humans|*Somites|Medaka|Transcription Factors|Gene Expression Regulation, Developmental|Zinc Fingers|Fish Proteins|Mesoderm|Genome 76 ZIC4 29367430 Clin. Cancer Res. 2018 10.1158/1078-0432.CCR-17-2719 14 0 0 48 76 ZMIZ1 30402962 Ann. Hum. Genet. 2018 10.1111/ahg.12293 3 0 0 162 Humans|*Colitis, Ulcerative|*Celiac Disease|Bayes Theorem|Crohn Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|Risk Factors|PTPN2 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 2 65 ZMIZ1 30350386 Genes Chromosomes Cancer 2018 10.1002/gcc.22674 2 0 0 162 Humans|Genome-Wide Association Study|*Colorectal Cancer|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Proportional Hazard Model|Genetic Loci|Prognosis|CDH1 protein, human|Cadherins|Disease-Free Survival|Genotype|Antigens, CD|*Colonic Neoplasms|Risk|MYNN protein, human|Kruppel-Like Transcription Factors 65 ZMIZ1 30285234 Hum. Mol. Genet. 2018 10.1093/hmg/ddy324 0 0 0 162 interferon regulatory factor-8|*Vitamin D|*Interferon Regulatory Factors|*Vitamins|*Cell Differentiation|Monocytes|*Autoimmune Disease|ZMIZ1 protein, human|Dendritic Cells|*Disease Susceptibility|Genotype|*Cholestanes 65 ZMIZ1 30076146 Blood 2018 PMC6148450 10.1182/blood-2018-02-835850 0 3 0 162 ZMIZ1 protein, human|*Transcription Factors|*Cell Differentiation|Receptor, Notch1|Signal Transduction|Proto-Oncogene Proteins c-myc|T-Lymphocytes 65 ZMIZ1 29795407 Pharmacogenomics J. 2018 10.1038/s41397-018-0025-5 7 0 0 162 Humans|*Methotrexate|*Genome-Wide Association Study|*Rheumatoid Arthritis|Antirheumatic Agents|Single Nucleotide Polymorphism|Drug Therapy, Combination|Severity of Illness Index|Treatment Outcome 65 ZMIZ1 29491472 J. Hum. Genet. 2018 10.1038/s10038-018-0422-2 2 0 0 162 Humans|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|*Coronary Artery Disease|Genetic Predisposition to Disease|Enhancer Elements, Genetic|Quantitative Trait Loci|Chromatin|ZMIZ1 protein, human|Transcription Factors 65 ZNF185 30446632 Aging (Albany NY) 2018 PMC6286825 10.18632/aging.101639 0 0 0 64 *Tumor Suppressor Protein p53|*DNA Damage|LIM Domain Proteins|Transcription Factor|Cytoskeletal Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Chromatin|Microfilament Proteins 24 ZNF185 30337687 Oncogene 2018 PMC6755960 10.1038/s41388-018-0509-4 7 0 0 64 *Squamous Cell Carcinoma|*Cell Differentiation|PDLIM4 protein, human|DNA-Binding Proteins|Transcription Factor|Epidermal Cells|Tumor Suppressor Proteins|Keratinocytes|LIM Domain Proteins|Epidermis|Head and Neck Neoplasms|Gene Expression Regulation|Trans-Activators|Cell Proliferation|Cell Adhesion|Cell Line, Tumor|Cell Adhesion Molecules 24 ZNF185 30270484 J. Pept. Sci. 2018 10.1002/psc.3121 1 0 0 64 Humans|Mice|Male|Animals|Sperm Motility|*Fertility|Epididymis|Testis|Spermatozoa|Vaccines, Contraceptive|Sperm Count|Contraception, Immunologic|Seminiferous Tubules|peptide B|Contraceptive Agents, Male|Reproduction|Testosterone|Effects, Contraceptive|Antigens|ZNF185 protein, human|Cytoskeletal Proteins|LIM Domain Proteins 24 ZNF185 29293529 PLoS ONE 2018 PMC5749725 10.1371/journal.pone.0189887 4 4 0 64 Humans|*Massively Parallel Sequencing|*Disease Progression|Mutations|Exome|*Neoplastic Processes|DNA Copy Number Variations|Genomics|Whole Exome Sequencing 24 ZNF365 30500874 J Crohns Colitis 2018 10.1093/ecco-jcc/jjy197 2 0 0 33 Humans|*Genome-Wide Association Study|*Crohn Disease|Japan|Genetic Predisposition to Disease|Asian|Polymorphism, Single Nucleotide|Case-Control Studies|Genotype|RAP1A protein, human|*rap1 GTP-Binding Proteins 57 ZNF365 29719630 Oncotarget 2018 PMC5915097 10.18632/oncotarget.24719 4 0 0 33 *Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|*Soft Tissue Sarcomas|*Soft Tissue Neoplasms|Case-Control Studies|Risk Factors 57 ZNF469 30338343 Ophthalmologe 2018 10.1007/s00347-018-0796-8 0 0 0 19 Male|Humans|Child, Preschool|Brittle cornea syndrome 1|*Joint Instability|*Skin Abnormalities|Anterior segment mesenchymal dysgenesis|*Eye Abnormalities|DNA-Binding Proteins|*Mutations|Transcription Factors|Sclera|ZNF469 protein, human 49 ZNF469 29755127 Oncogene 2018 10.1038/s41388-018-0293-1 12 4 0 19 Humans|*RNA, Long Noncoding|*Triple-Negative Breast Cancer|Neoplasm Recurrence, Local|*Lung Neoplasms|Zinc Finger E-box-Binding Homeobox 1|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor|Up-Regulation|Biomarkers, Tumor|Signal Transduction|Apoptosis|ZEB1 protein, human|ZNF469 protein, human|Transcription Factors 49 ZNF469 29709596 Matrix Biol. 2018 10.1016/j.matbio.2018.04.013 11 0 0 19 Humans|*Ehlers-Danlos Syndrome|tenascin X|Tenascin|Collagen|Collagen Type III|Extracellular Matrix|Skin|Mutations|Bleeding|Contusions|PRDM5 protein, human|DNA-Binding Proteins|Transcription Factors 49 ZNF469 29346494 Invest. Ophthalmol. Vis. Sci. 2018 PMC5773233 10.1167/iovs.17-22173 12 0 0 19 *Syndromes|*Myopia|Refractive Errors|Hyperopia|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Eye Proteins 49 ZNF598 30293783 Mol. Cell 2018 PMC6224477 10.1016/j.molcel.2018.08.037 47 0 0 133 Humans|*Ribosomes|Ubiquitination|Ubiquitin|Protein Biosynthesis|Ribosomal Proteins|mRNA|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Ubiquitin-Protein Ligases|Carrier Proteins|HEK293 Cells|ZNF598 protein, human 20 ZNF598 29719242 Cell Rep 2018 PMC5951170 10.1016/j.celrep.2018.03.132 4 24 0 133 Humans|*Interferon|*Protein Biosynthesis|*Poxviruses|Ribosome|ribosomal protein S20|Ribosomal Proteins|Ubiquitin|Ubiquitination|mRNA, Polyadenylated|*Antiviral Agents|Carrier Proteins|HEK293 Cells|ZNF598 protein, human 20 ZNF598 29464043 Oncotarget 2018 PMC5814183 10.18632/oncotarget.23643 0 12 0 133 *Cell Survival|*Apoptosis Regulatory Proteins|*Ultraviolet Rays|Apoptosis|Short Hairpin RNA|DNA Damage|Cell Line, Tumor|Up-Regulation|Tumor Suppressor Protein p53|Phosphorylation|Transfection|*Cell Death|mRNA|Zinc Fingers 20 ZNF644 30021720 Yi Chuan 2018 10.16288/j.yczz.18-028 0 5 0 140 Male|Swine|Animals|*Sertoli Cells|*Apoptosis|Cell Proliferation|3' UTR|MicroRNAs|Spermatogenesis|Transfection|Cell Survival 20 ZNF91 30310315 Cancer Manag Res 2018 PMC6165778 10.2147/CMAR.S172710 2 0 0 55 Humans|*Stomach Neoplasms|DNA Copy Number Variations|ERBB2 protein, human|Receptor, ErbB-2|Gene Amplification|In Situ Hybridization, Fluorescence|Mutation 26 ZPBP2 29536159 Mamm. Genome 2018 10.1007/s00335-018-9743-x 1 0 0 22 Humans|Male|Female|Animals|Mice|Child|Genome-Wide Association Study|*Lipid Metabolism|*Zona Pellucida|*Lung|Asthma|*Hypersensitivity|DNA Methylation|Phenotypes|Egg Proteins|SNPs|Membrane Proteins|Promoter Regions, Genetic|Immunoglobulin E|Mice, Knockout|Neoplasm Proteins|sphingosine 1-phosphate|Lysophospholipids|Sphingosine 39 ZPBP2 29463315 Biol Sex Differ 2018 PMC5819645 10.1186/s13293-018-0169-7 1 6 0 22 Male|Female|Humans|*DNA Methylation|*Sex Differences|Promoter Regions, Genetic|Genotype|Phenotype|Membrane Proteins|Chromosomes, Human, X|Cell Line|Asthma 39 ZPBP2 29348612 Nat Commun 2018 PMC5773513 10.1038/s41467-017-02596-9 20 0 0 22 Child|Humans|United States|*Genome-Wide Association Study|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Latino|Whites|Transcription Factor|*Chromosome Structures|Logistic Models|Oncogene, myc|Cohort Studies 39 A2ML1 29084334 JAMA Neurol 2017 PMC5729739 10.1001/jamaneurol.2017.2807 5 1 0 58 *DNA Methylation|*Cognitive Decline|Alzheimer Disease|Brain|Lewy Bodies|*Relaxation|Magnetic Resonance Imaging 39 A4GALT 28586101 FEBS Lett. 2017 10.1002/1873-3468.12709 1 3 0 57 44 A4GALT 28194794 Transfusion 2017 10.1111/trf.13990 2 1 0 57 44 ABCF2 28112439 Mol. Carcinog. 2017 PMC5509336 10.1002/mc.22615 16 20 0 143 Humans|Female|*Cisplatin|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Drug Resistance, Neoplasm|Antineoplastic Agents|*Ovary|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|Viability, Cell|siRNA|*GA-Binding Protein Transcription Factor|RNA Interference|ABCF2 protein, human|ATP-Binding Cassette Transporters 33 ABHD11 28818073 Mol. Cancer 2017 PMC5561620 10.1186/s12943-017-0709-5 19 27 0 25 Humans|Female|*RNA, Long Noncoding|Neoplasms, Glandular and Epithelial|Carcinoma, Ovarian Epithelial|Cell Proliferation|Ovarian Neoplasms|Gene Expression Regulation, Neoplastic|rhoC GTP-Binding Protein|Cell Movement|MicroRNAs|Carcinogenesis|Cell Differentiation|Apoptosis|Cell Line, Tumor|Signal Transduction 32 ABHD11 28465236 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.04.145 3 0 0 25 Animals|Humans|*Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|*Yeast, Dried|Lipase|TYRP1 protein, human|*Lipids|Amino Acid Sequence|Lipid Metabolism|*Membrane Glycoproteins|Triglycerides|Sequence Alignment 32 ABHD11 28157695 Oncotarget 2017 PMC5438641 10.18632/oncotarget.14945 13 7 0 25 Humans|*RNA, Long Noncoding|*RNA, Anti-Sense|*Urinary Bladder Neoplasms|Cell Proliferation|Cell Migration|Gene Expression Regulation, Neoplastic|Apoptosis|Up-Regulation|Cell Line, Tumor|*Transcription Factors|RNA, Small Interfering|Tumorigenesis|Neoplasms, Glandular and Epithelial|Cell Transformation, Neoplastic|Disease Progression|*Phenotypes 32 abhd2 28813576 Invest. Ophthalmol. Vis. Sci. 2017 PMC5559178 10.1167/iovs.17-21734 3 1 0 142 Humans|*Age Related Macular Degeneration|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|Linkage Disequilibrium|Genome-Wide Association Study|European Continental Ancestry Group|Case-Control Studies|*Mitochondria|TRPM1 protein, human|TRPM Cation Channels|ABHD2 protein, human|Hydrolases 30 abhd2 28684316 Biochem. Biophys. Res. Commun. 2017 PMC5658124 10.1016/j.bbrc.2017.06.195 2 16 0 142 *Calcium|*Endoplasmic Reticulum|*Calcium, Dietary|A23187|*Hydrolases|Mitochondria|pyrrophenone|Pyrrolidines|Apoptosis|Cells, Cultured|Serine 30 abhd2 28507119 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5465908 10.1073/pnas.1700367114 21 4 0 142 Humans|Male|Female|*Calcium Channel|*Sperm|Sperm Motility|Spermatozoa Capacitation|Calcium Signaling|Progesterone|*Cell Membrane|*Calcium, Dietary|Fertility|*Triterpenoids|ABHD2 protein, human|Hydrolases 30 ABI3BP 29213343 Hered Cancer Clin Pract 2017 PMC5707812 10.1186/s13053-017-0082-9 4 2 0 65 Humans|*Exome|*Adenomatous Polyposis Coli|Colonic Polyps|Colorectal Cancer|Proto-Oncogene Proteins B-raf|ras Proteins|Microsatellite Instability|*Whole Exome Sequencing|Mutation|DNA Methylation|*Syndrome|Colon|Phenotype 27 ABI3BP 28593875 J Perinat Med 2017 10.1515/jpm-2016-0406 4 0 0 65 Infant, Newborn|Humans|Female|Pregnancy|*Pre-Eclampsia|*Fetal Growth Retardation|*Placenta|*Infant, Small for Gestational Age|*Gene Expression|Gene Expression Profiling|Case-Control Studies|*Delivery, Obstetric 27 ABI3BP 28441029 Am. J. Respir. Cell Mol. Biol. 2017 PMC5625220 10.1165/rcmb.2016-0220OC 8 0 0 65 Humans|Mice|Animals|*Mice, Inbred CBA|*Pulmonary Emphysema|*Smoke|Chronic Obstructive Pulmonary Disease|*Tobacco|*Emphysema|Smoking|Lung|Pulmonary Alveoli|Disease Models, Animal|Mice, Inbred Strains|Disease Susceptibility 27 ABTB1 29031853 Exp. Eye Res. 2017 10.1016/j.exer.2017.10.007 29 0 0 20 Humans|Uveal melanoma|*Prognosis|*Uveal Neoplasms|*Melanoma|Gene Modules|Gene Expression Profiling|Transcriptome|Gene Expression Regulation, Neoplastic|Gene Ontology|SLC17A7 protein, human|Vesicular Glutamate Transport Protein 1 31 ACAP2 28566286 J. Biol. Chem. 2017 PMC5512060 10.1074/jbc.M116.773333 4 53 0 127 *Weibel-Palade Bodies|*Exocytosis|von Willebrand Factor|TYRP1 protein, human|*Membrane Glycoproteins|rab GTP-Binding Proteins|Human Umbilical Vein Endothelial Cells|Cells, Cultured|Calcium|RNA, Small Interfering 26 ACOD1 29192676 Cell Res. 2017 PMC5799814 10.1038/cr.2017.153 4 1 0 3025 *RNA, Long Noncoding|*Infection, Viral|Virus Replication|Host-Pathogen Interactions|Interferons|RNA, Viral|Glutamic Oxaloacetic Transaminase 24 ACOD1 29074580 Science 2017 10.1126/science.aao0409 51 2 0 3025 Humans|Mice|Animals|*Interferon|*RNA, Long Noncoding|*Virus Replication|*Antiviral Agents|Infection, Viral|Viruses|Host-Pathogen Interactions|RNA, Viral 24 ACOD1 28477473 Int. Immunopharmacol. 2017 10.1016/j.intimp.2017.04.012 3 8 0 3025 *Reactive Oxygen Species|*NADPH Oxidase|*Histocompatibility Antigens Class I|ATP Binding Cassette Transporter, Subfamily B, Member 3|ATP Binding Cassette Transporter, Subfamily B, Member 2|Antigen Presentations|*Macrophages|STAT1 protein, human|STAT1 Transcription Factor|ATP-Binding Cassette Transporters|*Oxidation-Reduction|Major Histocompatibility Complex|Phosphorylation 24 ACOD1 28079476 J. Interferon Cytokine Res. 2017 10.1089/jir.2016.0097 4 1 0 3025 Humans|*Mimiviridae|*Interferon|*Antiviral Agents|Interferon-beta|Interferon Regulatory Factor-3|Host-Pathogen Interactions|Viral Proteins|Virus|Protein-Serine-Threonine Kinases|Signal Transduction|Macrophages|Promoter Regions, Genetic|IRG1 protein, human 24 ACRV1 28600885 Mol. Reprod. Dev. 2017 PMC5577912 10.1002/mrd.22851 0 3 0 6 Humans|Male|Mice|Animals|*Seminiferous Epithelium|Spermatogenesis|Spermatids|*DNA Binding Protein|Testis|Spermatocytes|Sertoli Cells|Sperm|Transcription Factors|Spermatogonia|Infertility, Male|RNA, Messenger|Histone|TDP-43 protein, human 57 ACRV1 28398669 Birth Defects Res 2017 PMC5462453 10.1002/bdr2.1002 5 0 0 6 Mice|Animals|Male|*Testis|*Organ Culture Techniques|Spermatogenesis|Spermatids|Seminiferous Tubules|Spermatogonia|Spermatozoa|Cell Differentiation 57 ACRV1 28278534 Semin. Reprod. Med. 2017 10.1055/s-0037-1599088 1 3 0 6 Humans|Male|*Testis|*DNA-Binding Proteins|Spermatogenesis|*RNA Splicing|Infertility, Male|*Gene Expression|RNA, Messenger|TDP-43 protein, human 57 ACRV1 28600885 Mol. Reprod. Dev. 2017 PMC5577912 10.1002/mrd.22851 0 3 0 6 Humans|Male|Mice|Animals|*Seminiferous Epithelium|Spermatogenesis|Spermatids|*DNA Binding Protein|Testis|Spermatocytes|Sertoli Cells|Sperm|Transcription Factors|Spermatogonia|Infertility, Male|RNA, Messenger|Histone|TDP-43 protein, human 57 ACRV1 28398669 Birth Defects Res 2017 PMC5462453 10.1002/bdr2.1002 5 0 0 6 Mice|Animals|Male|*Testis|*Organ Culture Techniques|Spermatogenesis|Spermatids|Seminiferous Tubules|Spermatogonia|Spermatozoa|Cell Differentiation 57 ACRV1 28278534 Semin. Reprod. Med. 2017 10.1055/s-0037-1599088 1 3 0 6 Humans|Male|*Testis|*DNA-Binding Proteins|Spermatogenesis|*RNA Splicing|Infertility, Male|*Gene Expression|RNA, Messenger|TDP-43 protein, human 57 ADAM29 28913673 Mol. Cell. Biochem. 2017 10.1007/s11010-017-3190-y 2 0 0 13 Humans|*Ligands|ADAM11 protein, human|ADAM Proteins|Integrins|Disintegrins|Cell Adhesion|Models, Molecular|*Catalysis|Tumor Suppressor Proteins 31 ADAMDEC1 29247567 Cancer Sci. 2017 PMC5797829 10.1111/cas.13469 5 3 0 24 Female|Humans|*Cisplatin|*Adenocarcinoma, Clear Cell|*Antineoplastic Agents|Ovarian Neoplasms|Apoptosis|Drug Resistance, Neoplasm|Cell Line, Tumor|*Ovary|Gene Expression Regulation, Neoplastic|ADAM8 protein, human|Membrane Protein|ADAM Proteins|Signal Transduction|*Cell Death|ADAM9 protein, human 42 ADAMDEC1 29185848 MAbs 2017 PMC5800386 10.1080/19420862.2017.1395541 2 0 0 24 Humans|*Proteolysis|*Disintegrins|ADAM Proteins|Epitopes|Blotting, Western|Antibodies, Monoclonal|*Protein Domains|ELISA|Immunoprecipitation 42 ADAMDEC1 29184442 Cancer Manag Res 2017 PMC5685135 10.2147/CMAR.S149002 6 6 0 24 Humans|*Exome|*Transcriptome|Colorectal Cancers|*Whole Exome Sequencing|Liver Neoplasms|DNA Copy Number Variations|Genomics|Mutation 42 ADAMDEC1 29178397 Am. J. Transplant. 2017 10.1111/ajt.14600 22 0 0 24 Humans|Endothelial Cells|Kidney Transplantation|Graft Rejection|T-Lymphocytes|NK Cells|Antibodies|*Transplantation, Homologous|Biopsy|CTLA4 protein, human|CTLA-4 Antigen|Allografts 42 ADAMDEC1 28512356 Sci Rep 2017 PMC5434015 10.1038/s41598-017-02203-3 10 6 0 24 Rats|Animals|*Probiotics|*Rats, Zucker|*Intestinal Mucosa|*Obesity|Lactobacillus rhamnosus|Bifidobacterium|*Inflammation|Lactobacillus|PTGS1 protein, human|*Cyclooxygenase 1|*Upregulation|*Downregulation|*Receptor, Endothelin B|*Transcriptional Activation|Ptgs1 protein, rat|Membrane Proteins 42 ADAMDEC1 28455445 J. Biol. Chem. 2017 PMC5473217 10.1074/jbc.M116.771642 6 8 0 24 epidermal growth factor precursor|*Epidermal Growth Factor|*Blood Platelets|*Endopeptidases|ADAM Proteins|Protein Precursors|Plasma Membranes|ADAM17 Protein|*Hydrolysis|ErbB Receptors|Membrane Proteins|Protein Processing, Post-Translational|Protease Inhibitors|*Membrane 42 ADARB2 29093448 Nat Commun 2017 PMC5665907 10.1038/s41467-017-01459-7 11 1 0 83 34 ADARB2 28874676 Sci Rep 2017 PMC5585319 10.1038/s41598-017-09754-5 14 5 0 83 34 ADARB2 28560309 Alzheimers Dement (Amst) 2017 PMC5440281 10.1016/j.dadm.2017.04.004 6 0 0 83 34 ADARB2 28514750 Oncotarget 2017 PMC5522036 10.18632/oncotarget.17462 15 4 0 83 34 ADARB2 28353150 J. Physiol. Biochem. 2017 10.1007/s13105-017-0560-6 6 0 0 83 34 AFAP1L2 29212154 Oncotarget 2017 PMC5706800 10.18632/oncotarget.20967 3 9 0 160 Humans|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Apolipoprotein A-V|Metabolic Syndrome|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Cholesterol, HDL|Risk Factors 30 AFAP1L2 28849225 Mol Med Rep 2017 10.3892/mmr.2017.7279 1 2 0 160 Humans|*Colorectal Cancer|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Cell Movement|RNA, Small Interfering|Cell Proliferation|AKT1 protein, human|Protein Kinase B|Gene Expression Regulation, Neoplastic|Gene Knockdown Techniques|Vimentin|Cell Line, Tumor|Adaptor Proteins, Signal Transducing|Signal Transduction|*Colonic Neoplasms|Phosphorylation 30 AFAP1L2 28351223 Thyroid 2017 10.1089/thy.2016.0673 6 0 0 160 Humans|*Sequestosome-1 Protein|*Thyroid Cancers|*Oncogene Fusion|Thyroid Cancer, Papillary|Carcinoma, Papillary|Proto-Oncogene Proteins c-ret|Proto-Oncogene Proteins B-raf|Proto-Oncogene Proteins c-ets|Carcinoma|Receptor, trkC|Gene Rearrangement|Oncogene Proteins, Fusion|Neoplasms, Radiation-Induced|Repressor Proteins|Mutation|RET protein, human|SQSTM1 protein, human|AFAP1L2 protein, human 30 AGAP1 28965411 J. Proteome Res. 2017 10.1021/acs.jproteome.7b00223 1 0 0 202 Humans|Male|*Proteomics|Proteome|Databases, Protein|Tandem Mass Spectrometry|Amino Acid Sequence|Post-Translational Modifications|Alternative Splicing|Peptides|Hippocampus|Open Reading Frames|*Chromosome|ACTN4 protein, human|Actinin|CPNE5 protein, human|Carrier Proteins 25 AGAP1 28550165 Mol. Cell Proteomics 2017 PMC5629260 10.1074/mcp.RA117.000011 8 1 0 202 Mice|Animals|*Protein Interaction Maps|*Microtubule-Associated Proteins|Microtubules|Tubulin|Actin|Phosphorylation|3T3-L1|Cytoskeletal Proteins|Protein Binding|Insulin|Adipocytes|Plasma Membrane|CLASP2 protein, mouse|AGAP1 protein, mouse|GTPase-Activating Proteins 25 AGAP1 28430047 Small GTPases 2017 PMC6548297 10.1080/21541248.2017.1308850 2 1 0 202 ADP-Ribosylation Factors|GAP Protein|Actin|Actin Cytoskeleton|Cell Movement|Adaptor Proteins, Signal Transducing|Protein Binding|Kinesin 25 AJAP1 29213071 Sci Rep 2017 PMC5719082 10.1038/s41598-017-17136-0 3 2 0 135 Humans|Mice|Animals|*Genome-Wide Association Study|*Latinos|*Electrocardiography|Long QT Syndrome|SNPs|Linkage Disequilibrium|KCNQ1 Potassium Channel|Genotype|Genetic Predisposition to Disease|Arrhythmias, Cardiac|Risk Factor|Bves protein, mouse|Muscle Proteins|Cell Adhesion Molecules 58 AJAP1 29115565 Int. J. Oncol. 2017 PMC5743336 10.3892/ijo.2017.4184 2 4 0 135 Humans|Animals|Mice|*Glioma|Glioblastoma Multiforme|*Cell Motility|Primary Malignant Brain Tumors|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Gene Knockdown|siRNA|Xenograft Model Antitumor Assays|Signal Transduction|AJAP1 protein, human|Cell Adhesion Molecules 58 AJAP1 29050343 Oncotarget 2017 PMC5642618 10.18632/oncotarget.20369 2 0 0 135 Humans|*Carcinoma, Hepatocellular|*Hepatectomy|*Liver Neoplasms|Reproducibility of Results|Neoplasm Recurrence, Local|Prognosis|Biomarkers, Tumor 58 AJAP1 28855354 Clin. Cancer Res. 2017 10.1158/1078-0432.CCR-17-1222 31 1 0 135 58 AJAP1 28852427 Clin Epigenetics 2017 PMC5571486 10.1186/s13148-017-0392-9 12 2 0 135 *Carcinoma, Squamous Cell|*Prognosis|*Mouth Neoplasms|Head and Neck Squamous Cell Carcinoma|CpG Islands|DNA Methylation|Epigenesis, Genetic|Biomarkers, Tumor|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|*Gene Expression|*Biochemical Phenomena|Head and Neck Neoplasms 58 AJAP1 28814615 Reproduction 2017 PMC5630521 10.1530/REP-17-0345 10 6 0 135 Cattle|Animals|*Blastocyst|Blastocyst Inner Cell Mass|Cell Lineage|Embryo Culture Techniques|Embryonic Development|Epiblast|Embryo, Mammalian|Gene Expression Regulation, Developmental|Trophoblasts|Cell Differentiation|Octamer Transcription Factor-3|*Gene Expression|*B-Lymphocytes 58 AJAP1 28634045 Cancer Lett. 2017 10.1016/j.canlet.2017.06.007 4 9 0 135 epidermal growth factor receptor VIII|*Glioma|*ErbB Receptors|Glioblastoma|Brain Neoplasms|*Cytoskeleton|Signal Transduction|*Epigenesis, Genetic|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Apoptosis 58 AJAP1 28595284 Mol. 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Reprod. 2017 10.1093/molehr/gax034 2 0 0 135 Humans|Male|Female|*Transcriptome|*Infertility|Blastocyst|Embryo Implantation|Embryo Culture Techniques|Fertilization in Vitro|Embryonic Development|Gene Expression Profiling|Gene Expression Regulation, Developmental|Polycystic Ovary Syndrome 58 AJAP1 28514750 Oncotarget 2017 PMC5522036 10.18632/oncotarget.17462 15 4 0 135 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Epigenome|*Epigenetic|DNA Methylation|CpG Islands|Epigenesis, Genetic|Tumorigenesis|Liver|*Mutations|Hepatitis B|Genome-Wide Association Study|Cell Transformation, Neoplastic 58 AJAP1 28483980 Biol Open 2017 PMC5483013 10.1242/bio.022335 2 17 0 135 *Endothelial Cells|Esophageal Neoplasms|Esophageal Squamous Cell Carcinoma|*Cytoskeleton|Glioma|CDH1 protein, human|E Cadherin|*Microtubules|*Neovascularization, Pathologic|Adherens Junction|Cell Movement|Cell Adhesion Molecules|Gene Expression Regulation, Neoplastic|Antigens, CD|Cell Line, Tumor|Cell Membrane 58 AJAP1 28383563 Cell Death Dis 2017 PMC5477574 10.1038/cddis.2017.126 7 37 0 135 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Neoplasm Recurrence, Local|Zinc Finger E-box-Binding Homeobox 1|*Carcinogenesis|Epithelial-Mesenchymal Transition|*Signal Transduction|Gene Expression Regulation, Neoplastic|MicroRNAs|*Catenins|Cell Movement|*Neoplastic Processes|Cell Proliferation|Cell Line, Tumor|Transcription Factors|Disease Progression|ZEB1 protein, human|AJAP1 protein, human 58 AKTIP 28983474 Front Cell Infect Microbiol 2017 PMC5613121 10.3389/fcimb.2017.00417 20 46 0 222 Helicobacter pylori|Helicobacter Infections|Antigens, Bacterial|Gastric Mucosa|Bacterial Proteins|Virulence Factors 46 AKTIP 28911005 Carcinogenesis 2017 PMC6248579 10.1093/carcin/bgx073 3 2 0 222 Humans|Carcinoma, Hepatocellular|Liver Neoplasms|*Proto-Oncogene Proteins c-akt|DNA Methylation|Azacitidine|CpG Islands|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Line, Tumor|Decitabine|Gene Silencing|Down-Regulation|Cell Movement|mRNA|Signal Transduction|Cell Proliferation|*Neoplastic Processes 46 AKTIP 28457660 Acta Histochem. 2017 10.1016/j.acthis.2017.04.003 2 7 0 222 *Mesenchymal Stem Cells|*Proto-Oncogene Proteins c-akt|Mesenchymal Stem Cell Transplantation|*Signal Transduction|Myocardial Infarction|Myocardium|*Neovascularization, Pathologic|MTOR protein, human|TOR Serine-Threonine Kinases|Neovascularization, Physiologic|Heart|Left Ventricular Function|Apoptosis|Vascular Endothelial Growth Factor A|Fibrosis 46 AKTIP 28417539 Mol Oncol 2017 PMC5467492 10.1002/1878-0261.12067 16 44 0 222 *Carcinoma, Hepatocellular|multidrug resistance-associated protein 1|*Sirtuin 1|*Proto-Oncogene Proteins c-akt|*Liver Neoplasms|*Multidrug Resistance|Multidrug Resistance-Associated Proteins|Usp22 protein, human|*Thiolester Hydrolases|ATP Binding Cassette Transporter, Subfamily B, Member 1|Drug Resistance, Neoplasm|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B|*Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Hep G2 Cells|Neoplasm Proteins 46 Alx3 29215096 J. 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Genet. 2017 10.1038/s10038-017-0358-y 0 0 0 60 Humans|Frontonasal dysplasia|*Exome|*Craniofacial Abnormalities|*Whole Exome Sequencing|*Face|*Codon, Nonsense|Homozygote|Phenotypes|Homeodomain Proteins|Mutation|Pedigree|SH2D3A protein, human|Adaptor Proteins, Signal Transducing|ALX3 protein, human 65 Alx3 29161290 PLoS ONE 2017 PMC5697817 10.1371/journal.pone.0187611 1 0 0 60 Mice|Humans|Animals|*Networks, Gene|Gene Ontology|Transcription Factors|Gene Expression Profiling|*Gene Expression|Algorithms|*Biochemical Phenomena 65 Alx3 28701710 Sci Rep 2017 PMC5507922 10.1038/s41598-017-05422-w 2 8 0 60 Mice|Animals|*SR-BI Receptor|*Neural Tube|*Lipoprotein|*Biological Transport|Scavenger Receptors, Class B|High Density Lipoproteins|Cholesterol|*Neurulation|Vitamin E|Sac, Yolk 65 Alx3 28608508 Chemistry 2017 10.1002/chem.201701553 0 0 0 60 *Aluminum|Molecular Structure|Crystallography, X-Ray|Models, Molecular 65 Alx3 28429019 Dalton Trans 2017 10.1039/c7dt00726d 1 0 0 60 *Uranium|*Inorganic Chemicals|Models, Molecular 65 Alx3 28341857 Sci Rep 2017 PMC5428206 10.1038/s41598-017-00334-1 2 14 0 60 Pregnancy|Female|Mice|Animals|*Glucose|*Pregnancy in Diabetics|*Oxidative Stress|Neural Tube Defects|Hyperglycemia|PAX3 Transcription Factor|Paired Box Transcription Factors|Embryo, Mammalian|Gene Expression Regulation, Developmental|Apoptosis|Diabetes Mellitus, Experimental|Binding Site|Alx3 protein, mouse|Homeodomain Proteins 65 Alx3 28287460 Molecules 2017 PMC6155411 10.3390/molecules22030446 3 0 0 60 Humans|*Leukemia, Myeloid, Acute|Gene Expression Regulation, Leukemic|cdc25 Phosphatases|Cell Signaling|Antineoplastic Agents|Cell Proliferation|Viability, Cell|Cyclin-Dependent Kinases|Cell Differentiation|Cell Division|Gene Expression Profiles 65 AMIGO2 29182684 PLoS ONE 2017 PMC5705125 10.1371/journal.pone.0188697 5 0 0 92 Humans|*Colorectal Cancer|*Transcriptome Analysis|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Transcriptome|Gene Ontology|Biomarkers, Tumor|Databases, Genetic|*Colonic Neoplasms 28 AMIGO2 29149598 Mol. Cell 2017 PMC5993436 10.1016/j.molcel.2017.11.004 17 22 0 92 Humans|*Melanoma|*Antineoplastic Agents|Nuclear Proteins|Cell Cycle Proteins|Transcription Factors|Protein-Serine-Threonine Kinases|Apoptosis|Cell Line, Tumor|Cell Survival|Epigenomic|PTK7 protein, human|Cell Adhesion Molecules|Receptor Protein-Tyrosine Kinases 28 AMIGO2 29098329 Arch. Toxicol. 2017 10.1007/s00204-017-2107-6 3 4 0 92 *Acetylation|*Histones|ochratoxin A|*Protein Processing, Post-Translational|ochratoxin B|*Ochratoxins|Acetyltransferases, Histone|Chromatin|*Gene Expression|Promoter Regions, Genetic|*Mycotoxins 28 AMIGO2 28611293 Oncotarget 2017 PMC5522256 10.18632/oncotarget.18186 5 1 0 92 *Pancreatic Cancer|Protein Interaction Maps|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Computational Biology|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Transcriptome|Signal Transduction 28 AMIGO2 28272394 Sci Rep 2017 PMC5341090 10.1038/srep43567 3 8 0 92 Humans|Mice|Animals|*Endothelial Cells|*Up-Regulation|*Liver Neoplasms|*Liver|Cell Adhesion|*Hepatocytes|Colonic Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Transcriptional Activation|Lung Neoplasms|*Cell Count|Amigo2 protein, mouse|Membrane Proteins|Nerve Tissue Proteins 28 AMIGO2 28119027 Brain Behav. Immun. 2017 10.1016/j.bbi.2017.01.009 1 3 0 92 Animals|Mice|*Encephalomyelitis, Autoimmune, Experimental|Glycogen Synthase Kinase 3|Th1 Cells|Th17 Cells|Adoptive Transfer|IL10 protein, human|IL10|Mice, Knockout|Lymphocyte Activation|Spleen|Interferon-gamma|Multiple Sclerosis|Mice, Inbred C57BL|Cell Differentiation|Amigo2 protein, mouse|Membrane Proteins|Nerve Tissue Proteins 28 ANGPTL1 28904065 Cancer Res. 2017 10.1158/0008-5472.CAN-17-0579 16 15 0 255 Carcinoma, Hepatocellular|Liver Neoplasms|STAT3 Transcription Factor|Signal Transduction|Janus Kinase 2|Cell Line, Tumor|Cell Movement|Cell Proliferation|Downregulation|Xenograft Model Antitumor Assays|Apoptosis|Interleukin-6 67 ANGPTL1 28731166 Mol Med Rep 2017 PMC5646985 10.3892/mmr.2017.7063 4 6 0 255 Humans|*Prognosis|Early Detection of Cancer|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Mapping|Computational Biology|Gene Expression Regulation, Neoplastic|Transcriptome|Databases, Genetic|Software|Signal Transduction 67 ANGPTL1 28606130 J. 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Biol. 2017 PMC5237311 10.1186/s12862-016-0859-x 2 3 0 255 Humans|Animals|Conserved Sequence|Evolution, Molecular|Amino Acid Sequence|Phylogeny|Fishes|*Skin|*Angiopoietins|Wound Healing|Regeneration|*Conservation of Natural Resources 67 ANGPTL6 29033485 Indian J Pharmacol 2017 PMC5637136 10.4103/ijp.IJP_261_16 1 1 0 149 Humans|*Glycated Hemoglobin A|*Diabetes Mellitus, Type 2|*Blood Glucose|Hypoglycemic Agents|Insulin Sensitivity|*Blood Proteins|Biomarkers|Angiopoietins 66 ANGPTL6 28955777 Biochem Biophys Rep 2017 PMC5614699 10.1016/j.bbrep.2017.07.005 9 21 0 149 Humans|*Up-Regulation|Diabetes Mellitus, Type 2|mRNA|Cell Hypoxia|Hypoxia|Sleep Apnea Syndromes|Cells, Cultured|Hepatocytes 66 ANGPTL6 28663568 Sci Rep 2017 PMC5491520 10.1038/s41598-017-03054-8 19 2 0 149 Child|Animals|Humans|*Pediatric Obesity|*Rodent|*Obesity, Severe|Chromogranins|Genetic Predisposition to Disease|GTP-Binding Protein alpha Subunits, Gs|Receptors, Leptin|Mutation|Case-Control Studies|ANGPTL6 protein, human|Angiopoietin-like Proteins 66 ANGPTL6 28184000 J. Endocrinol. 2017 10.1530/JOE-16-0549 5 3 0 149 Animals|*Oxidative Phosphorylation|fibroblast growth factor 21|*Fibroblast Growth Factors|*Mitochondria|*Obesity|*Adiposity|Energy Metabolism|Cell Cycle Proteins|Adipose Tissue|mtDNA|Oxidation-Reduction 66 ANKRD17 29073189 PLoS ONE 2017 PMC5658091 10.1371/journal.pone.0186844 2 30 0 122 Mice|Animals|*Mice, Inbred C57BL|HAMP protein, human|Hepcidin|EPO protein, human|*Erythropoietin|TFR2 protein, human|Receptors, Transferrin|*Epoetin Alfa|HJV protein, human|Hemochromatosis Protein|Anemia, Iron-Deficiency|GPI-Linked Proteins|Serine Endopeptidases|*Homeostasis|*Protein Transport|Iron|Liver|Mice, Knockout 24 ANKRD17 28580594 Head Neck 2017 10.1002/hed.24798 0 0 0 122 Humans|*Polymorphism, Single Nucleotide|*Oral Cancer|*Genotypes|Genetic Predisposition to Disease|Gene Frequency|Alleles|Carcinoma, Squamous Cell|Case-Control Studies|Odds Ratio|*Asian Continental Ancestry Group|Risk Factors|Tobacco Chewing|Smoking 24 ANP32E 29067888 World J. Biol. Psychiatry 2017 10.1080/15622975.2017.1396357 1 1 0 183 36 ANP32E 28856239 eNeuro 2017 PMC5569379 10.1523/ENEURO.0040-17.2017 10 24 0 183 Rats|Animals|*Histones|Nucleosomes|RNA Polymerase II|Transcriptional Activation|Transcription, Genetic|Transcription Factors|*Neurons|Promoter Regions, Genetic|Eukaryotic Cells 36 ANP32E 28220627 Cancer Med 2017 PMC5345683 10.1002/cam4.1024 17 10 0 183 Humans|*Down-Regulation|*Cell Migration|MicroRNAs|Cell Proliferation|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|3' Untranslated Regions|Cell Line, Tumor|MCF-7 Cells|RNA Interference|mRNA|siRNA|*Neoplastic Processes|Prognosis|MIRN141 microRNA, human 36 ANXA10 29061538 J. Urol. 2017 10.1016/j.juro.2017.09.141 2 0 0 63 *Urinary Bladder Neoplasms|Carcinoma, Transitional Cell|Cystoscopy|*Bladder|Specificity|Biomarkers, Tumor|ROC Curve|*Urinary Tract|Cytodiagnosis|RNA, Messenger 62 anxa8 29085461 Oncol Lett 2017 PMC5649615 10.3892/ol.2017.6751 1 10 0 85 TP53 protein, human|*Tumor Suppressor Protein p53|*Up-Regulation|Genes, p53|Mutation|Carcinoma, Squamous Cell|*Transcriptional Activation 33 anxa8 28774834 Semin. Cancer Biol. 2017 PMC5794649 10.1016/j.semcancer.2017.07.007 19 38 0 85 Humans|*Forkhead Box Proteins|Forkhead Box Protein O3|Forkhead Box Protein O1|*Neoplastic Processes|Signal Transduction|Proto-Oncogene Proteins c-akt|mRNA|Phosphorylation|Gene Expression Regulation, Neoplastic|Apoptosis|MIRN622 microRNA, human|MicroRNAs 33 anxa8 28712927 Exp. Cell Res. 2017 10.1016/j.yexcr.2017.07.015 3 8 0 85 Rats|Animals|*Annexin A6|*Lipid Droplets|*Fatty Acids|*Liver|*Adipogenesis|*Lipogenesis|Adipocytes|Hepatocytes|Signal Transduction|Cell Line|Biological Transport 33 anxa8 28680125 Sci Rep 2017 PMC5498634 10.1038/s41598-017-03493-3 2 28 0 85 *Annexin A8|Fenretinimide|*Neurons|Cell Differentiation|Cell Line|CALB2 protein, human|Calretinin|Retinal Pigment Epithelium|*Phenotype|Transdifferentiations, Cell|Antineoplastic Agents|Epithelial Cells|Real Time PCR|siRNA|Downregulation|Cell Cycle Arrest|Cultured Cells|Cell Proliferation 33 anxa8 28060564 Cell Adh Migr 2017 PMC5479451 10.1080/19336918.2016.1264559 4 5 0 85 Humans|*Annexin A8|*Vascular Endothelial Growth Factor A|Human Umbilical Vein Endothelial Cells|Vascular Endothelial Growth Factor Receptor-2|Neovascularization, Pathologic|Cell Adhesion|Neovascularization, Physiologic|Cell Movement|Signal Transduction|Cell Proliferation|Phosphorylation 33 AOAH 29156909 Ann Palliat Med 2017 10.21037/apm.2017.09.03 1 0 0 51 Humans|*Cancer Pain|*Genetic Markers|Palliative Care|Pain Management|Bone Neoplasms|Pain Measurement|Quality of Life 51 AOAH 29118019 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2017 PMC5899250 10.1152/ajpregu.00239.2017 3 1 0 51 Humans|Mice|Animals|acyloxyacyl hydrolase|*Mice, Inbred C57BL|*BALB C Mice|Bladder Pain Syndrome|*Carboxylic Ester Hydrolases|Pelvic Pain|Cystitis|Pseudorabies Virus|Urinary Bladder|Allodynia|Disease Models, Animal 51 AOAH 28622363 PLoS Pathog. 2017 PMC5489216 10.1371/journal.ppat.1006436 8 32 0 51 Mice|Animals|*Lipopolysaccharides|acyloxyacyl hydrolase|*Carboxylic Ester Hydrolases|*Acute Lung Injury|Lung|Macrophages, Alveolar|Macrophages, Peritoneal|Endotoxins|Lipase|Infection, Gram-Negative Bacterial|Immune Tolerance|Gram-Negative Bacteria|Cells, Epithelial 51 AOAH 28400412 Am. J. Physiol. Endocrinol. Metab. 2017 10.1152/ajpendo.00372.2016 3 0 0 51 Rats|Animals|*Endotoxemia|*Diet, Western|*Ileum|Obesity|Lipopolysaccharides|Permeability|Intestinal Mucosa|Adiposity|Bacteria|Bifidobacterium 51 APOBEC3D 29153851 Cell Chem Biol 2017 PMC5775913 10.1016/j.chembiol.2017.10.007 22 10 0 83 Humans|*APOBEC Enzymes|vif Gene Products, Human Immunodeficiency Virus|Cytosine Deaminase|APOBEC-3G Deaminase|Cytidine Deaminase|HIV-1|Simian Immunodeficiency Virus|HIV Infections|Mutation|Mutagenesis|Cell Line|*DNA Viruses|APOBEC3G protein, human|APOBEC3B protein, human|Minor Histocompatibility Antigens 32 ARL4C 29270876 Ann. Surg. Oncol. 2017 10.1245/s10434-017-6292-6 4 2 0 179 *Stomach Neoplasms|Carcinoma, Signet Ring Cell|Prognosis|Neoplasm Invasiveness|Peritoneal Neoplasms|*Peritoneum|Adenocarcinoma|Lymphatic Metastasis|Biomarkers, Tumor|Cell Movement|Adenocarcinoma, Mucinous|Gene Expression Regulation, Neoplastic|Cell Proliferation|Survival Rate|Tumor Cells, Cultured|RNA, Messenger|Real-Time Polymerase Chain Reaction 38 ARL4C 28855378 Mol. Biol. Cell 2017 PMC5662259 10.1091/mbc.E17-01-0059 7 33 0 179 FLNA protein, human|*Filamins|*ADP-Ribosylation Factor|*Cell Migration|Actin|Actin Cytoskeleton 38 ARL4C 28053143 J. Biochem. 2017 10.1093/jb/mvw069 5 0 0 179 *Cell Transformation, Neoplastic|*Tumorigenesis|*Signal Transduction|*Catenins|ADP-Ribosylation Factor|Wnt Proteins|beta Catenin|Lung Cancers|Gene Expression Regulation, Neoplastic|Colorectal Neoplasms|Cells, Epithelial|*Intercellular Signaling Peptides and Proteins 38 ARVCF 29277685 Heart Rhythm 2017 10.1016/j.hrthm.2017.12.023 2 0 0 78 Humans|Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|*Fibrinogen|Colombia|*Complement|Desmoplakins|Skin|Endemic Diseases|*Hemostatics|Heart 79 ARVCF 29214101 Dermatol Pract Concept 2017 PMC5718118 10.5826/dpc.0704a02 0 3 0 78 Humans|Animals|Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|*Armadillos|*DiGeorge Syndrome|Colombia|*Skin|*Cell Junction|*B-Lymphocytes|Desmoplakins|Endemic Diseases|Antigens|Immunohistochemistry|IgA receptor|South America 79 ARVCF 29152726 Int. J. 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Dis. 2017 PMC5481205 10.1016/j.nbd.2017.03.006 3 18 0 78 Mice|Humans|Animals|COMT protein, human|*Catechol O-Methyltransferase|L Dopa|Dyskinesia, Drug-Induced|Antiparkinson Agents|Corpus Striatum|Oxidopamine|3-methoxytyramine|Dopamine|Parkinsonian Disorders|Mice, Transgenic|Disease Models, Animal|Proto-Oncogene Proteins c-fos 79 ASTL 28983121 Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2017 10.5507/bp.2017.036 0 0 0 52 *Orbital Fractures|*Orbit|*Drug Repositioning|Diplopia|Oculomotor Muscles|Prolapse|Hernia|Retrospective Studies|Treatment Outcome|Tomography, X-Ray Computed|Mathematical Model 96 ASTL 28928490 Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2017 10.5507/bp.2017.037 0 0 0 52 *Orbital Fractures|Diplopia|Orbit|Retrospective Studies|Follow-Up Studies|Treatment Outcome|Reconstructive Surgical Procedures|Tomography, X-Ray Computed 96 ASTL 28911209 Mol. Hum. Reprod. 2017 PMC5909858 10.1093/molehr/gax040 4 1 0 52 Male|*Zona Pellucida|Zona Pellucida Glycoproteins|Fertilization|Oocytes|Fetuin-B|Fertilization in Vitro|Spermatozoa|*Cytoplasm|Metalloproteases|Gene Expression Regulation, Developmental 96 ASTN1 29090037 Clin Epigenetics 2017 PMC5655856 10.1186/s13148-017-0419-2 7 0 0 24 Humans|Female|Pregnancy|*Papillomavirus Infections|*Triage|*Real-Time Polymerase Chain Reaction|Cervical Intraepithelial Neoplasia|Uterine Cervical Neoplasms|Human papillomavirus 18|Human papillomavirus 16|Vaginal Smears|Colposcopy|Tests, HPV DNA|Early Detection of Cancer|Screening|DNA, Viral|DNA Methylation|Biomarkers, Tumor 40 ASTN1 28927462 Stem Cell Res Ther 2017 PMC5606115 10.1186/s13287-017-0645-8 0 4 0 24 Humans|*Polycystic Kidney, Autosomal Dominant|*Induced Pluripotent Stem Cells|TRPP Cation Channels|*Kidney|*Cell Differentiation|Mutations 40 ASTN1 28517363 IUBMB Life 2017 10.1002/iub.1641 1 0 0 24 Animals|Humans|*Cleavers|Neuroglia|Nerve Tissue Proteins|Neurons|Glycoproteins|Cell Movement|Cerebellum|Neurogenesis|Membrane Proteins|Proteolysis|Protein Domains 40 ASTN1 28506896 Semin. Cell Dev. Biol. 2017 10.1016/j.semcdb.2017.05.005 0 0 0 24 Animals|Humans|Mice|*Vertebrate|Membrane Attack Complex|Perforin|Nerve Tissue Proteins|Bone Morphogenetic Proteins|Retinoic Acid|Models, Molecular|Phenotypes 40 ASTN1 28448983 Dev. Neurosci. 2017 10.1159/000470902 4 0 0 24 Humans|Infant, Newborn|Animals|Female|Rats|Pregnancy|*Fetal Growth Retardation|Hedgehog Proteins|Neurogenesis|Cerebellum|*Infant, Small for Gestational Age|Neuroglia|Brain|Animals, Newborn|Fetuses|Astrocytes|Uterus 40 ASTN1 28100779 J. Biol. Chem. 2017 PMC5336181 10.1074/jbc.M116.768077 1 1 0 24 Mice|Animals|*Proteolysis|Membrane Proteins|Nerve Tissue Proteins|Aspartic Acid Endopeptidases|invariant chain|Antigens, Differentiation, B-Lymphocyte|Histocompatibility Antigens Class II|Transcription Factors|Neurons|Astn1 protein, mouse|Glycoproteins 40 ASTN2 28940097 Hum. Genet. 2017 10.1007/s00439-017-1843-2 19 0 0 61 Humans|*Intellectual Disability|*Genetic Heterogeneity|Exome|Genes, Recessive|Pedigree|Mutations|Base Sequence|Family|ZFAT protein, human|Transcription Factors 47 ASTN2 28540026 Mol Autism 2017 PMC5441062 10.1186/s13229-017-0137-9 107 2 0 61 Humans|*Genome-Wide Association Study|*Autism Spectrum Disorder|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype 47 ASTN2 28517363 IUBMB Life 2017 10.1002/iub.1641 1 0 0 61 Animals|Humans|*Cleavers|Neuroglia|Nerve Tissue Proteins|Neurons|Glycoproteins|Cell Movement|Cerebellum|Neurogenesis|Membrane Proteins|Proteolysis|Protein Domains 47 ASTN2 28506896 Semin. Cell Dev. Biol. 2017 10.1016/j.semcdb.2017.05.005 0 0 0 61 Animals|Humans|Mice|*Vertebrate|Membrane Attack Complex|Perforin|Nerve Tissue Proteins|Bone Morphogenetic Proteins|Retinoic Acid|Models, Molecular|Phenotypes 47 ASTN2 28456618 J. Allergy Clin. Immunol. 2017 10.1016/j.jaci.2017.04.007 2 4 0 61 *Dermatitis, Atopic|*Psoriasis|Skin|*Eczema|*Administration, Cutaneous|Keratinocytes|*Protein Tyrosine Phosphatase|*Peptides|Cells, Cultured 47 ASTN2 28452372 Sci Rep 2017 PMC5408227 10.1038/srep45040 30 0 0 61 Humans|Genome-Wide Association Study|HapMap|Allele Frequency|Genotyping Techniques|Genotype|Polymorphism, Single Nucleotide|Genome, Human|Software|African Americans 47 ASTN2 28100779 J. Biol. Chem. 2017 PMC5336181 10.1074/jbc.M116.768077 1 1 0 61 Mice|Animals|*Proteolysis|Membrane Proteins|Nerve Tissue Proteins|Aspartic Acid Endopeptidases|invariant chain|Antigens, Differentiation, B-Lymphocyte|Histocompatibility Antigens Class II|Transcription Factors|Neurons|Astn1 protein, mouse|Glycoproteins 47 ASTN2 28098162 Nat Commun 2017 PMC5253632 10.1038/ncomms13624 58 1 0 61 Humans|Genome-Wide Association Study|*Genetic Loci|*Hippocampal Formation|Alzheimer Disease|Genetic Predisposition to Disease|Episodic Memory|Organ Size|Brain|Cognition|MSRB3 protein, human|Methionine Sulfoxide Reductases|MAST4 protein, human|Microtubule-Associated Proteins|Protein-Serine-Threonine Kinases 47 ASTN2 28058730 Clin. Genet. 2017 10.1111/cge.12962 1 0 0 61 Humans|Genome-Wide Association Study|Case-Control Studies|*Chinese|*Migraine|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Transcription Factors|Genotype|DNA-Binding Proteins|Gene Frequency|Alleles|Cohort Studies|Genes, Regulator|TRPM Cation Channels|Risk Factors 47 ATG2B 29113029 FEBS Lett. 2017 10.1002/1873-3468.12901 16 0 0 89 Animals|*Lipid Droplets|Autophagy-Related Proteins|Autophagosomes|*Autophagy|Vesicular Transport Proteins|Membrane Proteins|Endoplasmic Reticulum|*Membranes 48 ATG2B 28820312 Autophagy 2017 PMC5788475 10.1080/15548627.2017.1359381 19 2 0 89 Rats|Animals|Autophagy-Related Proteins|Autophagosomes|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|Autophagy|Vesicular Transport Proteins|Membrane Proteins|Carrier Proteins|Endoplasmic Reticulum|Saccharomyces cerevisiae|Signal Transduction|ATG18 protein, S cerevisiae|Saccharomyces cerevisiae Proteins 48 ATG2B 28800131 Cell Death Differ. 2017 PMC5686350 10.1038/cdd.2017.133 19 0 0 89 Humans|CASP8 protein, human|*Caspase 8|*Autophagy|*Apoptosis|Autophagosome|CASP8 and FADD-Like Apoptosis Regulating Protein|Autophagy-Related Proteins|Fas-Associated Death Domain Protein|Signal Transduction|Cell Survival|HeLa Cells|NF-kappa B 48 ATG2B 28761177 Sci Rep 2017 PMC5537226 10.1038/s41598-017-07270-0 3 1 0 89 Humans|*Squamous Cell Carcinoma of Head and Neck|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Head and Neck Neoplasms|Gene Frequency|Case-Control Study|Carcinoma, Squamous Cell|Genotype|*Autophagy|Risk Factors|Alcohol Consumption 48 ATG2B 28561066 Nat Commun 2017 PMC5460038 10.1038/ncomms15637 31 60 0 89 *AMP-Activated Protein Kinases|*Autophagy|Autophagy-Related Protein-1 Homolog|Autophagy-Related Proteins|Autophagosomes|MTOR protein, human|TOR Serine-Threonine Kinases|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|Intracellular Signaling Peptides and Proteins|Phagosomes|Protein-Serine-Threonine Kinases|Signal Transduction|Vesicular Transport Proteins|Membrane Proteins|Phosphorylation|Lysosomes|Protein Binding 48 ATG2B 28444727 Br. J. Haematol. 2017 10.1111/bjh.14713 4 4 0 89 Humans|*Myeloproliferative Disorders|JAK2 protein, human|Janus Kinase 2|Calreticulin|Genetic Predisposition|Mutation|Haplotypes|Hematologic Neoplasms|Mutations, Germline|LNK protein, human|Proteins|RBBP6 protein, human|Carrier Proteins|DNA-Binding Proteins 48 ATL2 29130376 Mol. Plant Microbe Interact. 2017 10.1094/MPMI-07-17-0181-R 3 0 0 95 Animals|*Herbivory|jasmonic acid|Oxylipins|Cyclopentanes|Arabidopsis thaliana|Pseudomonas syringae|Botrytis|Arabidopsis Proteins|Salicylic Acid|Gene Expression Regulation, Plant|Plant Growth Regulators|Ethylenes|Plant Diseases|Disease Resistance|*Insects|cutin|Membrane Lipids|Signal Transduction 23 ATRN 28924386 Int. J. Biol. Sci. 2017 PMC5599910 10.7150/ijbs.19203 0 11 0 64 Animals|*Zebrafish|Zebrafish Proteins|Gastrulation|*Morphogenesis|Actomyosin|Actin Cytoskeleton|Actin|Cell Movement 82 ATRN 28493104 Neurogenetics 2017 10.1007/s10048-017-0515-7 0 1 0 64 Humans|Pelizaeus-Merzbacher Disease|ATRN protein, human|Membrane Proteins|Myelin Proteolipid Protein|Mutation|Hypotonia|Myelin Sheath|Introns|Phenotype|Homozygote|Central Nervous System|Brain|cDNA 82 ATRNL1 29263335 Sci Rep 2017 PMC5738366 10.1038/s41598-017-17120-8 4 2 0 17 30 BANK1 29070082 Biol Sex Differ 2017 PMC5657123 10.1186/s13293-017-0153-7 6 0 0 136 Male|Female|Genome-Wide Association Study|*Quantitative Trait Loci|*Lupus Erythematosus, Systemic|SNPs|Genetic Predisposition to Disease|Sjogren's Syndrome|Gene Frequency|Genotype|Autoimmune Diseases|Case-Control Studies|B Cells 86 BANK1 28925718 Autoimmunity 2017 10.1080/08916934.2017.1377191 1 1 0 136 Humans|TNFRSF14 protein, human|*Receptors, Tumor Necrosis Factor, Member 14|protein-tyrosine kinase p55(blk)|*src-Family Kinases|*Rheumatoid Arthritis|Genetic Predisposition to Disease|Epistasis, Genetic|Polymorphism, Single Nucleotide|Genotype|Chinese|Genome-Wide Association Study|Alleles|Case-Control Studies|Adaptor Proteins, Signal Transducing|Odds Ratio|Membrane Proteins|MMEL1 protein, human|Neprilysin 86 BANK1 28466820 Cell. Mol. Biol. (Noisy-le-grand) 2017 10.14715/cmb/2017.63.3.6 0 0 0 136 Humans|Allele|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Autoimmune Diseases|Adaptor Proteins, Signal Transducing|Genotype|Rheumatoid Arthritis|Lupus Erythematosus, Systemic|Membrane Proteins|Case-Control Studies|Odds Ratio|Sclerosis, Systemic|BANK1 protein, human 86 BANK1 28146432 Oncotarget 2017 PMC5362490 10.18632/oncotarget.14856 8 5 0 136 Humans|*Head and Neck Squamous Cell Carcinoma|dinophysistoxin 1|*Epigenetic|DNA Methylation|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Cell Line, Tumor|Downregulation|Epigenesis, Genetic|Genes, Tumor Suppressor|DTX1 protein, human|Ubiquitin-Protein Ligases 86 BARHL1 28956815 Genes (Basel) 2017 PMC5664095 10.3390/genes8100245 2 31 0 73 Animals|Mice|Female|*Alzheimer Disease|estrogen receptor alpha, human|*Estrogen Receptor 1|*Downregulation|Brain|BDNF protein, human|Brain-Derived Neurotrophic Factor|*Functions, Cognitive|Neurons|Nerve Tissue Proteins|Cerebellum|Neurotrophin 3|Homeodomain Proteins|Memory|Neurogenesis|Repressor Proteins|Medulloblastoma|Knockout Mouse 35 BARHL1 28592888 Leukemia 2017 10.1038/leu.2017.176 11 1 0 73 Adult|Humans|Proteins, Homeotic|T-ALL|Receptors, Antigen, T-Cell, gamma-delta|Leukemia-Lymphoma, Adult T-Cell|Cell Differentiation|BARX2 protein, human 35 BASP1 29277653 Toxicol In Vitro 2017 10.1016/j.tiv.2017.12.016 8 5 0 707 Humans|arsenite|*Arsenites|*Epithelial-Mesenchymal Transition|*Cells, Epithelial|*Hepatocytes|*Stem Cell|MicroRNAs|Cell Transformation, Neoplastic|*Liver|Bronchi|*Phenotype|CDH1 protein, human|N-Cadherin|Liver Cancer|Cell Line|Signal Transduction|Antigens, CD|Basic Helix-Loop-Helix Transcription Factors 136 BASP1 29197380 J Orthop Surg Res 2017 PMC5712098 10.1186/s13018-017-0674-0 0 6 0 707 *MicroRNAs|*Data Analysis|*Microarray Analysis|Gene Regulatory Networks|Gene Expression Profiling|Gene Ontology|Gene Expression Regulation, Neoplastic|*Arthritis|*Autoantibodies 136 BHLHA15 28361902 Sci Rep 2017 PMC5374460 10.1038/srep45867 3 22 0 200 66 BHLHA15 28174210 Genes Dev. 2017 PMC5322730 10.1101/gad.285684.116 24 1 0 200 66 BHLHA15 28170182 Stem Cells Transl Med 2017 PMC5442728 10.5966/sctm.2016-0083 13 3 0 200 Humans|*Hydrogel|*Cell Differentiation|Salivary Glands|Stem Cells|Acinar Cells|Cells, Cultured|*Progenitor B-Cells|Xerostomia|Lineages, Cell|Spheroids, Cellular|Cell Proliferation|Adult Stem Cells|Parotid Gland|Basement Membrane|Saliva|AMY1A protein, human|Salivary alpha-Amylases 66 BHLHA15 28158262 PLoS ONE 2017 PMC5291466 10.1371/journal.pone.0169677 2 5 0 200 Humans|Mice|Animals|*Proteome|Chromatography, Liquid|Quality of Life|Tandem Mass Spectrometry|*Gland, Salivary|IL6 protein, human|*B Cell Differentiation Factor|Sjogren's Syndrome|Xerostomia|Co-culture|Transcription Factor|Basic Helix-Loop-Helix Transcription Factors|Mesenchymal Stem Cells|Proteomics|Cells, Cultured|Cells, Epithelial|Cell Differentiation|Regeneration 66 BLID 28792102 Chemistry 2017 PMC5639379 10.1002/chem.201703057 6 1 0 49 *Salts|Ethers|Onium Compounds|Alcohols|Catalysis|Molecular Structure|Oxidation-Reduction|Electron 187 BMP2K 28565766 Exp Ther Med 2017 PMC5443164 10.3892/etm.2017.4191 3 9 0 204 Humans|Infant, Newborn|*Hip Dislocation, Congenital|Pedigree|*Mutation|Exome|Heterozygote|Polymorphism, Single Nucleotide|Exon|Genomics|*Databases, Genetic|Bone Morphogenetic Proteins 23 BMP2K 28231331 PLoS ONE 2017 PMC5322933 10.1371/journal.pone.0172430 6 4 0 204 Humans|*Mesenchymal Stem Cells|*Fetal Blood|Co-culture|Cell Differentiation|Antigens, CD34|Hematopoietic Stem Cells|Bone Marrow Cells|Cell Culture Techniques|Cells, Cultured|Cell Proliferation|Number, Cell|*Adult Stem Cells|Flow Cytometry 23 BMPER 29121877 BMC Genomics 2017 PMC5680825 10.1186/s12864-017-4278-1 11 0 0 173 Pregnancy|Female|Swine|Animals|Haplotypes|Gene Frequency|Breeding|Genotype|Sus scrofa|Genes, Lethal|Genes, Recessive|Homozygote|Polymorphism, Single Nucleotide|Genome|*Survey 86 BMPER 29093060 J. Exp. Med. 2017 PMC5716029 10.1084/jem.20162012 9 5 0 173 Mice|Animals|*Mesonephros|*Hematopoietic Stem Cells|*Gonad|*Aorta|BMP4 protein, human|Bone Morphogenetic Protein 4|Stromal Cells|Signal Transduction|Gene Expression Regulation, Developmental|Cell Line|Hematopoietic Stem Cell Transplantation|Mice, Inbred C57BL|Cells, Cultured 86 bnc1 29287803 J. Dermatol. Sci. 2017 10.1016/j.jdermsci.2017.12.003 0 0 0 179 Humans|*Epidermal Cells|*Progenitor Cells|Epidermis|Keratinocytes|Wound Healing|Cells, Cultured 94 bnc1 29212200 Oncotarget 2017 PMC5706846 10.18632/oncotarget.21397 6 1 0 179 Humans|*Adenocarcinoma|Pancreatic Carcinoma|*Pancreatic Cancer|*DNA Methylation|*Promoter Regions, Genetic|Prognosis|Biomarkers, Tumor|*B-Lymphocytes|*Plasma|Cell Free DNA 94 bnc1 28857158 Int. J. Cancer 2017 10.1002/ijc.31024 10 0 0 179 Humans|Pancreatic Carcinoma|*Pancreatic Cancer|*Adenocarcinoma|*Cell Free DNA|*Prognosis|*DNA Methylation|*Promoter Regions, Genetic|CpG Islands|Epigenesis, Genetic|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|TNM Classification|NEUROG1 protein, human|Nerve Tissue Proteins|PCR|Specificity|Genes, cdc|Basic Helix-Loop-Helix Transcription Factors 94 BNC2 29212900 Circ Cardiovasc Genet 2017 PMC5728702 10.1161/CIRCGENETICS.117.001811 2 1 0 85 Humans|*Blood Pressure|Genome-Wide Association Study|*Molecular Epidemiology|*Potassium|*Blood Pressure Determination|*Sodium Chloride, Dietary|Hypertension|*Sodium Chloride|Sodium, Dietary|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genotype|*Epistasis, Genetic 77 BRAC1 28442756 Sci Rep 2017 PMC5431371 10.1038/s41598-016-0007-2 6 19 0 0 Humans|Mice|Animals|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|*Triple-Negative Breast Cancer|PARP Inhibitors|Phthalazines|Antineoplastic Agents|Poly(ADP-ribose) Polymerases|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Proliferation|Apoptosis|Piperazines|Structure-Activity Relationship|Mice, Nude|Drug Discovery|*Cell Death 40 BRAC1 28415599 Oncotarget 2017 PMC5482636 10.18632/oncotarget.16422 7 0 0 0 Humans|BRCA1 protein, human|*BRCA1 Protein|BRCA2 protein, human|BRCA2 Protein|*Pancreatic Cancer|*Polymorphism, Genetic|Germ-Line Mutation|Genes, BRCA2|Prognosis|*Chinese|Genetic Predisposition to Disease|Mutation, Missense 40 BRSK1 28795405 Acta Psychiatr Scand 2017 10.1111/acps.12778 14 0 0 135 Humans|*Veterans|*Stress Disorders, Post-Traumatic|*DNA Methylation|Combat Disorders|Vietnam Conflict|Epigenesis, Genetic 48 BRSK1 28596382 J. Biol. Chem. 2017 PMC5535023 10.1074/jbc.M117.776260 8 0 0 135 Mice|Animals|*RNA, Long Noncoding|*Carcinoma, Squamous Cell|*Skin Neoplasms|*Downregulation|*Cell Differentiation|Gene Expression Regulation, Neoplastic|Keratinocyte|Cell Movement|Cell Proliferation|Cell Line, Tumor|Gene Expression Profiling|RNA, Messenger|Signal Transduction 48 BRSK1 28118297 Menopause 2017 PMC5443693 10.1097/GME.0000000000000817 0 0 0 135 Female|Humans|*Menopause|*Survivors|Single Nucleotide Polymorphisms|*Cancer Survivors|Genetic Association Studies|*Ovarian Diseases|Genotype|Age Factors 48 BRWD3 29166413 PLoS Genet. 2017 PMC5699827 10.1371/journal.pgen.1007087 14 2 0 50 Humans|*Mutation Rate|*Multiple Myeloma|European Continental Ancestry Group|African Americans|African Continental Ancestry Group|Gene Frequency|Exome|interferon regulatory factor-4|Interferon Regulatory Factors|Translocation, Genetic|Genomics|BCL7A protein, human|Microfilament Proteins|Oncogene Proteins|BRWD3 protein, human|Transcription Factors 25 BRWD3 29089422 Genes Dev. 2017 PMC5710144 10.1101/gad.305201.117 11 6 0 50 Animals|*Methylation|*Tudor Domain|*Histones|2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine|Histone-Lysine N-Methyltransferase|*Protein Processing, Post-Translational|Drosophila Proteins|Drosophila melanogaster|Chromatin|DNA-Binding Proteins|Transcription Factors|Lysine 25 Bsx 29098545 Obes Surg 2017 10.1007/s11695-017-2980-3 8 0 0 24 Humans|*Non-alcoholic Fatty Liver Disease|*Obesity, Morbid|*Prevalence|*Caloric Restriction|*Bariatric Surgery|*Morbidity|Liver|Risk Factors 86 Bsx 29050091 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 10.3760/cma.j.issn.1673-0860.2017.10.006 0 0 0 24 86 Bsx 28951881 Orthop J Sports Med 2017 PMC5606346 10.1177/2325967117727262 9 0 0 24 *Policies|*Secondary School|*Athletics|*Death, Sudden|Developed Countries 86 Bsx 28822457 Zhonghua Yi Xue Za Zhi 2017 10.3760/cma.j.issn.0376-2491.2017.30.012 0 0 0 24 86 BTBD9 29209388 Psychiatry Investig 2017 PMC5714726 10.4306/pi.2017.14.6.830 0 2 0 90 *Genome-Wide Association Study|Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Transcription Factors|Nerve Tissue Proteins|Case-Control Studies 67 BTBD9 29033051 Sleep Med Rev 2017 10.1016/j.smrv.2017.08.002 6 0 0 90 Humans|*Restless Legs Syndrome|Genome-Wide Association Study|PTPRD protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Case-Control Studies|Polymorphism, Single Nucleotide|VDR protein, human|Vitamin D3 Receptor|Genotype|Transcription Factors|Nerve Tissue Proteins|Genes, Homeobox 67 BTBD9 28985340 DNA Res. 2017 PMC5824824 10.1093/dnares/dsx037 3 1 0 90 Cattle|Mice|Animals|Quantitative Trait Loci|Genome-Wide Association Study|*Genome Mapping|Breeding|*Genetics, Population|Polymorphism, Single Nucleotide|Fertility|Phenotype|Genomics 67 BTBD9 28640246 Genet. Med. 2017 10.1038/gim.2017.78 3 0 0 90 Humans|*Genome-Wide Association Study|Phenotype|Genome, Human|Genetic Association Studies|Genetic Predisposition to Disease|Genotype|Exome|Traits, Complex|Genomics|Genetic Variation|Saudi Arabia 67 BTBD9 28626420 Front Aging Neurosci 2017 PMC5454050 10.3389/fnagi.2017.00171 6 4 0 90 Humans|Pregnancy|Female|Aged|Aged, 80 and over|*Restless Legs Syndrome|Dopaminergic Agents|Dopamine Agonists|Dopamine|Myeloid Ecotropic Viral Integration Site 1 Protein|Iron|Brain|Circadian Rhythm|Opioids|Asia 67 BTBD9 28329290 Sleep 2017 10.1093/sleep/zsx028 7 0 0 90 Humans|*Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Homeodomain Proteins|Transcription Factors|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Neoplasm Proteins|Case-Control Studies|*Chinese|MAP2K5 protein, human|BTBD9 protein, human 67 BTBD9 28236139 J. Neurol. 2017 10.1007/s00415-017-8431-1 10 2 0 90 Animals|Humans|*Restless Legs Syndrome|*Dopamine|*Iron|Myeloid Ecotropic Viral Integration Site 1 Protein|Brain|Genes, Homeobox|Nerve Tissue Proteins|Sleep 67 BTG4 28922388 PLoS ONE 2017 PMC5602628 10.1371/journal.pone.0184902 4 0 0 17 Humans|*Cancer|*Prognosis|Gene Expression Regulation, Neoplastic|Tumor Suppressor Proteins 40 BTG4 28241740 BMC Cell Biol. 2017 PMC5327573 10.1186/s12860-017-0130-3 8 27 0 17 *DNA Demethylation|beta-thujaplicin|*Tropolone|DNA Methylation|DNA (Cytosine-5-)-Methyltransferase 1|DNA (Cytosine-5-)-Methyltransferases|*Monoterpenes|5-Methylcytosine|Epigenesis, Genetic|*Colon Cancer|Promoter Regions, Genetic|DNA-Binding Proteins|Nuclear Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|*Colon|Cell Cycle Arrest 40 C1QTNF6 29091876 Biomed. Pharmacother. 2017 10.1016/j.biopha.2017.10.091 1 6 0 110 Rats|Animals|*Mesangial Cells|*Cell Proliferation|Fibroblasts|Fibrosis|Transforming Growth Factor beta1|Kidney|Signal Transduction|Cells, Cultured|Kidney Diseases|Extracellular Matrix|Phosphorylation|Pathway, ERK|Cell Line|Downregulation|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|CTRP6 protein, rat|Adipokines 33 C1QTNF6 28726640 J. Biol. Chem. 2017 PMC5592665 10.1074/jbc.M116.766808 11 6 0 110 Humans|Mice|Animals|*Insulin Resistance|*Complement C1q|*Adipose Tissue|*Obesity|*Inflammation|TNF protein, human|*Tumor Necrosis Factor-alpha|Diet, High-Fat|Leptin|3T3-L1 Cells|Macrophages|TYRP1 protein, human|*Membrane Glycoproteins|Cytokines|Mice, Inbred C57BL|CTRP6 protein, mouse|Adipokines 33 C1QTNF6 28665696 Genet Test Mol Biomarkers 2017 10.1089/gtmb.2017.0009 0 0 0 110 Humans|*Polymorphism, Single Nucleotide|*Intergenic Region|*Asian Continental Ancestry Group|*Graves Disease|Genetic Predisposition to Disease|Genome-Wide Association Study|Genotype|Case-Control Studies|C1qTNF6 protein, human|Collagen 33 C1QTNF9B 29145717 Mol. Cells 2017 PMC5750709 10.14348/molcells.2017.0097 0 29 0 1 Animals|Humans|*Keratinocytes|TGFB1 protein, human|*Transforming Growth Factor beta1|*Apoptosis|*Cell Differentiation|Adiponectin|TNF protein, human|*Tumor Necrosis Factor-alpha|TYRP1 protein, human|*Membrane Glycoproteins|Cell Proliferation|Glycoproteins|Signal Transduction|Gene Expression Regulation|Adipocyte|Cytokines|*Lymphotoxin-alpha 38 C1QTNF9B 29070503 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2017 10.1152/ajpregu.00212.2017 4 0 0 1 Middle Aged|Humans|Aged|*Vascular Stiffness|*Complement C1q|Endothelial Cells|*Exercise Training|Sedentary Behavior|Oxygen Consumption|Pulse Wave Analysis|Exercise Therapy|NOS3 protein, human|Endothelial Nitric Oxide Synthase|Adiponectin|Abdominal Visceral Fat 38 C1QTNF9B 28743061 Diabetes Res. Clin. Pract. 2017 10.1016/j.diabres.2017.07.003 1 0 0 1 Humans|*Insulin Resistance|*Diabetes Mellitus, Type 2|Adiponectin|Adipokine|Glycoproteins 38 C1QTNF9B 28587104 Int J Mol Sci 2017 PMC5485929 10.3390/ijms18061097 6 25 0 1 Humans|oxidized low density lipoprotein|*Antioxidants|*AMP-Activated Protein Kinases|*Complement C1q|*Enzyme Induction|*Lipoproteins, LDL|NOS3 protein, human|Endothelial Nitric Oxide Synthase|Human Umbilical Vein Endothelial Cells|Oxidative Stress|Reactive Oxygen Species|TNF protein, human|*Tumor Necrosis Factor-alpha|TYRP1 protein, human|*Membrane Glycoproteins|Nitric Oxide|Proto-Oncogene Proteins c-akt|Endothelium, Vascular 38 C5orf42 29146704 Clin J Am Soc Nephrol 2017 PMC5718273 10.2215/CJN.05660517 8 0 0 15 Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Prospective Studies|Ciliopathy|*Kidney Disease|Membrane Proteins|Adaptor Proteins, Signal Transducing|Mutation|Pedigree|Heterogeneities, Genetic 24 C5orf42 28631893 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38336 1 0 0 15 Humans|Orofaciodigital syndrome 6|*Orofaciodigital Syndromes|Agenesis of Cerebellar Vermis|Meckel syndrome type 1|Ciliary Motility Disorders|Eye Abnormalities|Polycystic Kidney Diseases|Retinitis Pigmentosa|Encephalocele|Abnormalities, Multiple|*Alleles|Cerebellum|Retina|Mutation|Phenotype|Homozygote|Tctn1 protein, human|Membrane Proteins 24 C5orf42 28431631 J. Neurol. Sci. 2017 10.1016/j.jns.2017.02.065 2 0 0 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Neuroimaging|*Mutations|*Nervous System Malformations|Membrane Proteins|Magnetic Resonance Imaging|C5orf42 protein, human 24 C5orf42 28289185 J. Med. Genet. 2017 PMC5557276 10.1136/jmedgenet-2016-104436 13 15 0 15 *Oral-Facial-Digital Syndrome|Disease, Polycystic Kidney|Ciliary Motility Disorders|Abnormalities, Multiple|Encephalocele|Retinitis Pigmentosa|Heterozygote|Membrane Proteins|Mutation|Face 24 CALHM1 29195910 Neurosci. Lett. 2017 10.1016/j.neulet.2017.11.044 0 0 0 64 *Connexins|Gap Junctions|*Central Nervous System|Nerve Tissue Proteins|Cell Death|*Hypoxia|*Ischemia 84 CALHM1 29180673 Mol. Psychiatry 2017 10.1038/mp.2017.229 3 0 0 64 Mice|Animals|*Astrocytes|*Depression|Neurons|Hippocampus|Glia|Synaptic Transmission|Synaptic Plasticity|Adenosine Triphosphate|Mice, Knockout|Brain|Neuromodulator 84 CALHM1 29107294 Mol Metab 2017 PMC5681271 10.1016/j.molmet.2017.08.015 12 17 0 64 *Taste|*Ependymoglial Cells|Taste Buds|*Amino Acids|*Hypothalamus|Receptors, G-Protein-Coupled|Receptors, Metabotropic Glutamate|Cells, Glial|Glucose 84 CALHM1 28888730 Appetite 2017 10.1016/j.appet.2017.09.004 4 1 0 64 Adult|Humans|*Taste|*DNA Methylation|*Body Mass Index|*B-DNA|Taste Perception|Food Preferences|Eating|Obesity|Dietary Carbohydrates|*Dysgeusia|Genotype|CALHM1 protein, human|Membrane Glycoproteins|Calcium Channels 84 CALHM1 28828281 PeerJ 2017 PMC5564386 10.7717/peerj.3708 2 0 0 64 Animals|*Taste|*Phylogeny|*Reptiles|Evolution, Molecular|*Genomics|Receptors, G-Protein-Coupled|*Dysgeusia|*Snakes 84 CALHM1 28751666 Sci Rep 2017 PMC5532211 10.1038/s41598-017-07221-9 7 20 0 64 Mice|Animals|Connexins|Taste Buds|*Cells, Epithelial|Mucociliary Clearance|*Nose|Adenosine Triphosphate|Nerve Tissue Proteins|Carbenoxalone|Cells, Cultured|Panx1 protein, mouse|CALHM1 protein, mouse|Calcium Channels 84 CALHM1 28734079 J. Physiol. (Lond.) 2017 PMC5599488 10.1113/JP274164 7 1 0 64 *Lipoylation|Ion Channel Gating|Calcium Channels|*Membrane Microdomains|*Protein Processing, Post-Translational|Adenosine Triphosphate 84 CAMK1D 29137392 Oncotarget 2017 PMC5663564 10.18632/oncotarget.19996 10 13 0 112 Mice|Animals|*MicroRNAs|*Endothelial Cells|*Extracellular Vesicles|*Lung Cancer|Gene Expression Regulation, Neoplastic|Cell Transformation, Neoplastic|Real-Time Polymerase Chain Reaction|Lung Adenocarcinoma 60 CAMK1D 28607931 Biomed Res Int 2017 PMC5451767 10.1155/2017/3937893 3 2 0 112 Humans|*Diabetes Mellitus, Type 2|*Molecular Epidemiology|Mexico|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genotype|Cyclin-Dependent Kinase Inhibitor p16|Transcription Factors|Case-Control Studies 60 CAMK1D 28079868 J Perinatol 2017 10.1038/jp.2016.249 3 1 0 112 Female|Pregnancy|Humans|*Diabetes, Gestational|Diabetes Mellitus, Type 2|Genetic Predisposition to Disease|*CDKN2A Gene|Polymorphism, Single Nucleotide|Cyclin-Dependent Kinase Inhibitor p15|Genetic Association Studies|Genotype|Cyclin-Dependent Kinase Inhibitor p16|tRNA Methyltransferases|CDC123 protein, human|Cell Cycle Proteins|CAMK1D protein, human|Calcium-Calmodulin-Dependent Protein Kinase Type 1 60 CAMK1D 28077997 Am J Transl Res 2017 PMC5209477 8 3 0 112 Humans|Male|*RNA, Long Noncoding|*Androgens|Receptors, Androgen|Prostate Cancer|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|CAMK1D protein, human|Calcium-Calmodulin-Dependent Protein Kinase Type 1 60 CAMK2N1 28939038 Semin. Cell Dev. Biol. 2017 10.1016/j.semcdb.2017.09.025 5 0 0 115 *Synapse|Synaptic Plasticity|Long-Term Potentiation|Neurons|Synaptic Transmission|Nerve Tissue Proteins|Cytoskeletal Proteins|Memory|Hippocampus|Cognitive Function 60 CAMK2N1 28890075 Exp. Neurol. 2017 10.1016/j.expneurol.2017.09.004 1 0 0 115 Mice|Animals|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|*Down-Regulation|*Corpus Striatum|*Neostriatum|Receptors, N-Methyl-D-Aspartate|Synaptic Plasticity|Long-Term Potentiation|Excitatory Postsynaptic Potentials|Maze Learning|Hippocampus|Cognition Disorders|*Gray Matter|Phosphorylation|Cognition 60 CAMK2N1 28832060 Mol Biosyst 2017 10.1039/c7mb00379j 0 1 0 115 Humans|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|PDZ Domains|Hydrogen Bonding|Protein Binding|Quantum Theory|Halogens|Carrier Proteins 60 CAMK2N1 28714806 J. Neurogenet. 2017 10.1080/01677063.2017.1349121 1 0 0 115 Animals|Mice|Humans|*Alcohol Consumption|Addiction, Alcohol|*Cortex, Prefrontal|Ethanol|Alcoholic Intoxication|*Gene Expression Regulation|Alcoholics|Drinking|Brain|Reward|Compulsive Behavior|Disease Models, Animal|Transcriptome|CAMK2N1 protein, human|Proteins 60 CARD6 29248470 Am. J. Obstet. Gynecol. 2017 PMC5834399 10.1016/j.ajog.2017.12.009 26 2 0 74 Infant, Newborn|Humans|Adult|Pregnancy|Female|Child|*Genetic Predisposition to Disease|*Premature Birth|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Sequencing, Whole Exome|Fetal Membranes, Premature Rupture|Obstetric Labor, Premature|Genotype|Case-Control Studies|Phenotype|Mutations|DEFB1 protein, human|beta-Defensins|CARD8 protein, human|Neoplasm Proteins|CARD Signaling Adaptor Proteins 30 CARD6 29178652 Mol Genet Genomic Med 2017 PMC5702565 10.1002/mgg3.330 13 2 0 74 Pregnancy|Infant, Newborn|Humans|Female|Preterm Premature Rupture of the Membranes|*Fetal Membranes, Premature Rupture|Preterm Birth|*Prenatal Care|*Mutations|*Fetus|*Immunity, Innate|Extraembryonic Membranes|Gestational Age|Genetic Predisposition to Disease|Infant, Premature 30 CARD6 28814268 BMC Genomics 2017 PMC5559839 10.1186/s12864-017-3982-1 6 2 0 74 Sheep|Female|Animals|Humans|*Mastitis|*Genomics|Breeding|Milk|Quantitative Trait Loci|Lactation|Dairying|Breeding, Selective|Genotype|Phenotype|Sheep Diseases|Cell Count|Polymorphism, Single Nucleotide 30 CARTPT 28855710 Sci Rep 2017 PMC5577241 10.1038/s41598-017-10058-x 1 5 0 1118 Mice|Animals|*Body Composition|Pro-Opiomelanocortin|Arcuate Nucleus of Hypothalamus|Eating|Neuropeptide Y|Energy Metabolism|Feeding Behavior|Leptin|Homeostasis|Body Weight|Nerve Tissue Proteins|Gpr88 protein, mouse|Receptors, G-Protein-Coupled 39 CARTPT 28842817 Mol. Neurobiol. 2017 PMC5948251 10.1007/s12035-017-0750-9 7 10 0 1118 Rats|Animals|*Methamphetamine|*Nucleus Accumbens|Corticotropin-Releasing Hormone|Arginine Vasopressin|mRNA|DNA Methylation|Promoter Regions, Genetic|Gene Expression|Cyclic AMP Response Element-Binding Protein|Phosphorylation|AVP protein, human|Protein Precursors|Neurophysins|DNA|TET1 protein, rat|Dioxygenases 39 CARTPT 28827541 Sci Rep 2017 PMC5566486 10.1038/s41598-017-08898-8 7 8 0 1118 Rats|Animals|*Methamphetamine|*Nucleus Accumbens|*Oxytocin|*Punishment|Central Nervous System Stimulants|Self Administration|Rats, Sprague-Dawley|Corpus Striatum|Craving|Behavior, Animal|Behavior, Addictive|Brain|Upregulation|Gene Expression|Neuropeptides 39 CARTPT 28237718 Mol. Cell. Endocrinol. 2017 10.1016/j.mce.2017.02.027 0 2 0 1118 Humans|*Insulin Secretion|Diabetes Mellitus, Type 2|*Insulin-Secreting Cells|Insulin|Islets of Langerhans|Exocytosis|cocaine- and amphetamine-regulated transcript protein|Nerve Tissue Proteins|Glucose|*B-Lymphocytes|Transcription Factors|Gene Silencing 39 CARTPT 28234981 PLoS ONE 2017 PMC5325534 10.1371/journal.pone.0172687 2 0 0 1118 Cattle|Animals|Male|*Polymorphism, Single Nucleotide|*RNA-Seq|Genome|*Whole Exome Sequencing|Sequencing, Next-Generation|Breeding|Sequence Analysis, DNA|Genomics|Chromosome Mapping|INDEL Mutation|Transcriptome|Liver 39 CARTPT 28115581 Reproduction 2017 10.1530/REP-16-0657 1 0 0 1118 Sheep|Female|Animals|*Ovulation|Ovarian Follicle|Follicle Stimulating Hormone|Granulosa Cells|Luteinizing Hormone|Follicular Fluid|Receptors, FSH|Estradiol|Aromatase|RNA, Messenger 39 CASP5 29158166 Gene 2017 10.1016/j.gene.2017.11.032 0 2 0 94 Humans|Case-Control Studies|*Chinese|Single Nucleotide Polymorphism|*Rheumatoid Arthritis|Genetic Predisposition to Disease|Genetic Association Studies|Gene Frequency|Genotype|Ethnic Groups|Odds Ratio|Risk Factors|Caspases 152 CASP5 28738811 Environ Health 2017 PMC5525200 10.1186/s12940-017-0280-y 2 2 0 94 Humans|*Hearing Loss, Noise-Induced|*Case-Control Studies|*Caspase 3|Noise, Occupational|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Occupational Exposure|Logistic Models|Cadherins|*DNA Mutational Analysis|CASP3 protein, human 152 CASP5 28726636 J. Biol. Chem. 2017 PMC5582855 10.1074/jbc.M117.797217 13 2 0 94 Humans|*Pyroptosis|Caspase 1|Inflammasome|Caspases|Apoptosis Regulatory Proteins|Neoplasm Proteins|HEK293 Cells|Mutations|GSDMD protein, human 152 CASP5 28594934 PLoS ONE 2017 PMC5464765 10.1371/journal.pone.0178995 5 16 0 94 Glycogen Synthase Kinase 3|GW 6471|Oxazoles|PPAR alpha|Cell Cycle Arrest|Cell Cycle|Signal Transduction|Caspase-Dependent Apoptosis|Viability, Cell|Tyrosine|Cell Line, Tumor|Paraganglioma 152 CASP5 28422993 PLoS ONE 2017 PMC5396864 10.1371/journal.pone.0175153 4 39 0 94 *Th17 Cells|IL17A protein, human|Interleukin 17A|*Skin|IL1B protein, human|Interleukin-1beta|Inflammasome|S100A7 protein, human|Psoriasin|Keratinocytes|Psoriasis|NLR Family, Pyrin Domain-Containing 3 Protein|Epidermis|Dermatitis|Carrier Proteins|Signal Transduction|Caspases 152 CASP5 28196878 Mol. Cell Proteomics 2017 PMC5393394 10.1074/mcp.M116.064840 12 0 0 94 Humans|*Inflammasomes|*Macrophages|CASP4 protein, human|Caspases, Initiator|Innate Immune Response|Lipopolysaccharides|NLR Family, Pyrin Domain-Containing 3 Protein|Caspases|Inflammation|Interleukin-1beta|Cytosol|Gram Negative Bacteria 152 CASZ1 28945738 PLoS Genet. 2017 PMC5629033 10.1371/journal.pgen.1007011 5 7 0 1001 Adult|Humans|Mice|Animals|Familial dilated cardiomyopathy|*Cardiomyopathy, Dilated|Proteomics|*Heart|Transcription Factor|T-Box Domain Proteins|Cardiomyopathy|GATA4 Transcription Factor|Heterozygote|Mutation|Mutation, Missense|Heart Defects, Congenital|Cardiac Failure|Gene Expression Regulation|*Homeostasis|TBX20 protein, human|CASZ1 protein, human|DNA-Binding Proteins 61 CASZ1 28693373 Reprod Sci 2017 PMC6348426 10.1177/1933719117716779 9 0 0 1001 Adult|Infant, Newborn|Humans|Female|Pregnancy|*Birth Weight|*DNA Methylation|Intrauterine Growth Restriction|Epigenesis, Genetic|Placenta|Fetal Growth|Gestational Age|*Gene Expression|Gene Expression Regulation|Infant, Small for Gestational Age|*DNA|Cardiovascular Diseases 61 CCDC170 29230809 Ann. Hum. Genet. 2017 10.1111/ahg.12235 1 0 0 50 22 CCDC170 28840121 Int J Genomics 2017 PMC5559934 10.1155/2017/5831020 1 0 0 50 22 CCDC170 28761973 Calcif. Tissue Int. 2017 PMC5796546 10.1007/s00223-017-0308-x 3 1 0 50 22 CCDC170 28687497 EBioMedicine 2017 PMC5552109 10.1016/j.ebiom.2017.06.024 7 22 0 50 22 CCDC170 28537267 Nat Commun 2017 PMC5458088 10.1038/ncomms15539 47 9 0 50 22 CCL14 29128220 J. Dairy Sci. 2017 10.3168/jds.2017-13221 9 0 0 47 Pregnancy|Female|Humans|Cattle|Animals|WNT7A protein, human|Wnt Proteins|Preimplantation Embryo|Wnt11 protein, human|Endometrium|Estrous Cycle|Embryo Implantation|Embryonic Development|Progesterone|*Reproduction|Estrus|SFRP1 protein, human|Growth Factors|Fallopian Tubes|WNT5A protein, human|Wnt-5a Protein|Oestradiol|Oviduct 77 CCL14 28718365 Tumour Biol. 2017 10.1177/1010428317708900 7 0 0 47 Humans|*Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|Kaplan-Meier Analysis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Proportional Hazards Models|Survival Analysis|*Chemokines, CC|CCL14 protein, human|TMEM88 protein, human|Membrane Proteins 77 CCL14 28648867 Cytokine 2017 PMC5516773 10.1016/j.cyto.2017.05.023 7 1 0 47 Humans|Endothelial Cells|*Synovium|Fluid, Synovial|CCL15 protein, human|CCL23 protein, human|CCL18 protein, human|Rheumatoid Arthritis|Osteoarthritis|Macrophage Inflammatory Proteins|CCL20 protein, human|Chemokine CCL20|CCL21 protein, human|Chemokine CCL21|CCL22 protein, human|Chemokine CCL22|Inflammation|CCL16 protein, human|Chemokines, CC 77 CCL14 28415559 Oncotarget 2017 PMC5458226 10.18632/oncotarget.16358 22 2 0 47 *RNA, Long Noncoding|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*Mouth Mucosa|*Transcriptome Analysis|Oropharyngeal Neoplasms|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Biomarkers, Tumor|Squamous Cell Carcinoma of Head and Neck|Cell Line, Tumor|Carcinogenesis|Head and Neck Neoplasms 77 CCL14 28396316 J. Immunol. 2017 10.4049/jimmunol.1601175 11 1 0 47 Pregnancy|Humans|Female|*Trophoblasts|*Endothelial Cell|*Arterioles|Decidua|Placentation|NK Cell|Cell Migration|CXCL8 protein, human|Interleukin-8|*Arteries|CXCL6 protein, human|Chemokine CXCL6|Chemokines|Macrophages|Medium, Conditioned|Cells, Cultured 77 CCL14 28362325 Int J Mol Sci 2017 PMC5412327 10.3390/ijms18040742 10 59 0 47 Pregnancy|Cattle|Animals|Female|*CXC Chemokines|*Endometrium|Embryo Implantation|Trophoblast|CXCR3 protein, human|Receptors, CXCR3|Luteolysis|Cells, Epithelial|Oxytocin Receptor|CCL11 protein, human|Chemokine CCL11|Interferon Type I|RNA, Messenger 77 CCL14 28053103 J. Virol. 2017 PMC5331794 10.1128/JVI.02051-16 10 9 0 47 Humans|*Cytokines|HIV-1|HIV Long-Term Survivors|HIV Infections|Viral Load|CD4-Positive T-Lymphocytes|Virus Replication 77 CDC42EP4 28479334 J. Allergy Clin. Immunol. 2017 PMC5671374 10.1016/j.jaci.2017.04.016 4 9 0 127 Child|Humans|*Asthma|Th2 Cells|Th1 Cells|Obesity, Pediatric|*Upregulation|Inflammation|Cytokines|*Transcriptional Activation|*Genes, cdc 20 CDH16 28341240 Kidney Int. 2017 10.1016/j.kint.2016.09.005 3 0 0 53 Mice|Animals|LCN2 protein, human|*Neutrophil Gelatinase-Associated Lipocalin|*Longevity|*Disease Models, Animal|Potter Type III Polycystic Kidney Disease|*Disease, Polycystic Kidney|*Kidney|TRPP Cation Channels|Polycystic Kidney, Autosomal Dominant|TOR Serine-Threonine Kinases|Signal Transduction|Disease Progression|Phenotype|*Cysts 48 CDH19 28512649 eNeuro 2017 PMC5432758 10.1523/ENEURO.0307-16.2017 4 1 0 36 Male|Humans|Adult|Middle Aged|*Schwann Cells|Sciatic Nerve|Nerve Regeneration|Peripheral Nerve Injuries|Myelin Sheath|*Skin|Coculture Techniques 25 CDH19 28161066 Placenta 2017 10.1016/j.placenta.2016.12.009 8 0 0 36 Humans|Pregnancy|Female|*Choriocarcinoma, Non-gestational|Choriocarcinomas|Hydatidiform Mole|Gestational Trophoblastic Disease|Uterine Neoplasms|Microsatellite Repeats|Prognosis|*Genetic Profile|Biomarkers, Tumor|Placenta|Trophoblasts|Genomics 25 CDH22 29063123 Cell. Mol. Life Sci. 2017 10.1007/s00018-017-2689-4 5 0 0 30 Female|Mice|Rats|Animals|JAK2 protein, human|*Janus Kinase 2|*Catenins|Cadherins|Signal Transduction|*Female Germline Stem Cells|beta Catenin|Embryonic Stem Cells|Cell Differentiation|Cell Adhesion|Stem Cell Self-Renewal|RNA Interference|Germ Cells|Cdh22 protein, mouse|Jak2 protein, rat 26 CDH22 28991229 Oncogene 2017 PMC5770212 10.1038/onc.2017.372 7 1 0 30 Humans|CDH1 protein, human|E Cadherin|*Cell Migration|EIF4E2 protein, human|*RNA Cap-Binding Proteins|Neoplasm Invasiveness|Upregulation|Gene Expression Regulation, Neoplastic|Antigens, CD|*Hypoxia|Cell Line, Tumor|Cell Adhesion|RNA, Messenger|*Neoplastic Processes|Cell Hypoxia|Glioma|Transcriptional Activation 26 CDH22 28149335 Clin Epigenetics 2017 PMC5270318 10.1186/s13148-016-0309-z 2 4 0 30 Humans|Carcinoma, Ductal, Breast|DNA Methylation|CpG Islands|Cadherins|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Downregulation|Breast Cancer 26 CDHR1 29248581 Gene 2017 PMC6040674 10.1016/j.gene.2017.12.025 2 0 0 33 *Bipolar Disorder|*Exome|*Whole Exome Sequencing|Genetic Linkage|Pedigree|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Variation|Phenotype|Family 34 CDHR1 29053642 Genes (Basel) 2017 PMC5664133 10.3390/genes8100283 4 0 0 33 Humans|*Transcriptome|*Allelic Imbalance|Alleles|Polymorphism, Single Nucleotide|RNA, Messenger|*Retina|*Retinal Diseases 34 CDHR1 28885867 Ophthalmic Genet. 2017 10.1080/13816810.2017.1363244 3 0 0 33 Humans|*Retinal Degeneration|*Mutations|Electroretinography|DNA Mutational Analysis|Fluorescein Angiography|Phenotype|Genes, Recessive|Photoreceptor Cells, Vertebrate|Retina|Pedigree|Tomography, Optical Coherence|Nerve Tissue Proteins|CDHR1 protein, human|Cadherins 34 CDHR1 28765526 Sci Rep 2017 PMC5539332 10.1038/s41598-017-07117-8 5 1 0 33 Humans|*Retinal Dystrophies|Retinitis Pigmentosa|Cone Rod Dystrophy|*Mutations|Homozygote|DNA Mutational Analysis|Sequencing, Next-Generation|Pedigree|Retina|Eye Proteins|Phenotype|Alleles|CDHR1 protein, human|Nerve Tissue Proteins|Cadherins 34 CDHR1 28181551 Sci Rep 2017 PMC5299602 10.1038/srep42078 17 1 0 33 *Whole Exome Sequencing|*Protons|*Retinal Dystrophies|Exome|DNA Mutational Analysis|Pedigree|Sequencing, Next-Generation|Retina|Mutation 34 CDK2AP2 29235922 Epigenetics 2017 PMC5836972 10.1080/15592294.2017.1414128 1 0 0 664 Animals|Humans|*DNA Glycosylase|*DNA, Plant|*5-Methylcytosine|*DNA Methylation|*B-DNA|Arabidopsis|Arabidopsis Proteins|Genomic Imprinting|Gene Expression Regulation, Plant|Gene Silencing|Epigenesis, Genetic|Trans-Activators|Base Excision Repair 32 CDK2AP2 29068287 J. Gen. Virol. 2017 10.1099/jgv.0.000958 1 12 0 664 Humans|Mice|Animals|hepatitis B virus X protein|*DNA Methylation|*Trans-Activators|*Hepatocytes|*Tretinoin|*Apoptosis|Carcinoma, Hepatocellular|Hep G2 Cells|Downregulation|Liver Neoplasms|Promoter Regions, Genetic|CASP3 protein, human|Caspase 3|Tumor Suppressor Protein p53|Hepatitis B virus|Cell Line, Tumor|Upregulation 32 CDK2AP2 28523650 Proteomics 2017 10.1002/pmic.201600350 7 4 0 664 *Carcinoma, Hepatocellular|*Tumor Suppressor Protein p53|histidine-rich proteins|*Histidine|*Liver Neoplasms|*Apoptosis|*Signal Transduction|Cell Proliferation|Hep G2 Cells|Downregulation|Cell Cycle|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Survival|Ubiquitin-Specific Proteases 32 CECR2 29249292 Mol. Cell. Neurosci. 2017 10.1016/j.mcn.2017.10.008 7 0 0 63 Mice|Animals|*Chromatin Assembly and Disassembly|SMARCA1 protein, human|*Transcription Factors|ISWI protein|SMARCA5 protein, human|*Adenosine Triphosphatases|Chromosomal Proteins, Non-Histone|DNA-Binding Proteins|Chromatin|Nucleosomes|Protein Binding|*Neurodevelopmental Disorders|Brain|Smarca5 protein, mouse|Smarca1 protein, mouse 32 CECR2 28740608 ACS Med Chem Lett 2017 PMC5512139 10.1021/acsmedchemlett.7b00132 2 0 0 63 Schmid-Fraccaro syndrome|*Protein Domains|Binding Sites|Transcription Factors|Models, Molecular|Protein Processing, Post-Translational|Lysine|Drug Design|Acetylation|Chromosomes 32 CELF2 28935965 Nat Commun 2017 PMC5608764 10.1038/s41467-017-00631-3 5 7 0 220 *RNA Recognition Motif|mRNA Stability|*Molecular Conformation|Binding Sites|ELAV Proteins|3' Untranslated Region|Protein Binding|RNA, Messenger|Simulations, Molecular Dynamics|Amino Acid Sequence|NMR Spectroscopy|Nerve Tissue Proteins|RNA-Binding Domain 85 CELF2 28868343 Mol Cell Oncol 2017 PMC5540202 10.1080/23723556.2017.1325550 2 1 0 220 Humans|Male|Mice|Animals|Genes, Tumor Suppressor|PTEN Phosphohydrolase|DNA Transposable Elements|Prostatic Neoplasms|Mutagenesis|Gene Expression Regulation, Neoplastic|Mutation|Cell Line, Tumor|Signal Transduction 85 CELF2 28512194 Genome Res. 2017 PMC5538552 10.1101/gr.220517.117 9 2 0 220 Humans|*RNA Splicing|CELF Proteins|Alternative Splicing|Exon|RNA-Binding Proteins|Splicing Factors|Nerve Tissue Proteins|T Cells|RNA, Messenger|CELF2 protein, human 85 CELF2 28319090 Nat. Genet. 2017 PMC5409503 10.1038/ng.3817 12 6 0 220 Humans|Male|Mice|Animals|*Beauty|PTEN protein, human|*PTEN Phosphohydrolase|Genes, Tumor Suppressor|Insertional Mutagenesis|Mutation|DNA Transposable Elements|Prostate Cancer|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|CELF2 protein, human|CELF Proteins|Nerve Tissue Proteins 85 CELF4 29241933 Taiwan J Obstet Gynecol 2017 10.1016/j.tjog.2017.10.027 0 0 0 34 Pregnancy|Female|Humans|*Prenatal Diagnosis|Amniocentesis|Chromosome Disorders|Comparative Genomic Hybridization|Cytogenetic Analysis|Karyotyping|Mosaicism|Chromosome Deletion|In Situ Hybridization, Fluorescence|*Cytogenetics|SETBP1 protein, human|*Nuclear Proteins|CELF4 protein, human|CELF Proteins|DTNA protein, human|Neuropeptides|Dystrophin-Associated Proteins 43 CELF4 28711009 Sci. Total Environ. 2017 10.1016/j.scitotenv.2017.07.036 4 0 0 34 Animals|*Silica|*Zebrafish|*Nanoparticles|*Cardiovascular System|Embryo, Nonmammalian|miRNA|mRNA|Air Pollutants|Myocardial Contraction 43 CELF4 28679150 Chemosphere 2017 10.1016/j.chemosphere.2017.06.112 1 0 0 34 Animals|*Zebrafish|*Computational Biology|*Cardiovascular System|Embryo, Nonmammalian|Silicon Dioxide|*Microarray Analysis|miRNAs|Nanoparticles|mRNA|lead acetate|Organometallic Compounds|Bradycardia|Myocardial Contraction 43 CELF4 28433457 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.04.019 2 0 0 34 Humans|*Neuroticism|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Quantitative Trait Loci|Network, Gene|Brain 43 CELF4 28407444 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38205 4 2 0 34 Child|Adult|Humans|Female|*Autism Spectrum Disorder|Intellectual Disability|Developmental Disabilities|*RNA Binding Protein|Haploinsufficiency|Chromosome Deletion|Autism|Phenotype|CELF4 protein, human|CELF Proteins 43 CELSR2 29240829 PLoS ONE 2017 PMC5730153 10.1371/journal.pone.0189591 3 0 0 105 Humans|*Scoliosis|Genetic Linkage Analysis|Pedigree|Genetic Predisposition to Disease|Whole Exome Sequencing|Polymorphism, Single Nucleotide|CELSR1 cadherin, human|*Cadherins|CELSR2 protein, human|Case-Control Studies|Sweden|Japan 106 CELSR2 29186428 Hum. Mol. Genet. 2017 10.1093/hmg/ddx413 0 0 0 105 Mice|Animals|Genome-Wide Association Study|*Progranulins|Leukocytes, Mononuclear|Single Nucleotide Polymorphisms|Cohort Studies|Genetic Variation|CELSR2 protein, human|Cadherins|Adaptor Proteins, Vesicular Transport|Germany|Berlin|Europe|Finland|Cdh23 protein, mouse|Celsr2 protein, mouse 106 CELSR2 28753643 PLoS ONE 2017 PMC5533343 10.1371/journal.pone.0182115 3 6 0 105 Humans|darapladib|*Risk Factors|*Pharmacogenetic Analysis|*Pharmacogenetics|*Benzaldehydes|*Oximes|Lipoprotein-Associated Phospholipase A(2)|Phospholipase A2 Inhibitors|Coronary Heart Disease|Myocardial Infarction|Acute Coronary Syndrome|*Cardiovascular System|Genotype|FRMD5 protein, human|Tumor Suppressor Proteins 106 CELSR2 28734144 Arch. Oral Biol. 2017 10.1016/j.archoralbio.2017.07.008 4 0 0 105 Mice|Animals|*Cell Polarity|*Odontogenesis|Tooth Germs|In Situ Hybridization|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Molar|RNA, Messenger|Signal Transduction|Gene Expression 106 celsr3 29240829 PLoS ONE 2017 PMC5730153 10.1371/journal.pone.0189591 3 0 0 177 Humans|*Scoliosis|Genetic Linkage Analysis|Pedigree|Genetic Predisposition to Disease|Whole Exome Sequencing|Polymorphism, Single Nucleotide|CELSR1 cadherin, human|*Cadherins|CELSR2 protein, human|Case-Control Studies|Sweden|Japan 78 celsr3 28754314 Neuroscience 2017 10.1016/j.neuroscience.2017.07.040 4 0 0 177 Mice|Animals|*Ganglia, Spinal|Axons|Spinal Cord|Calcitonin Gene-Related Peptide|Sensory Receptor Cells|tropomyosin-related kinase-B, human|Receptor, trkB|Mice, Transgenic|Cadherins|Gene Expression Regulation, Developmental|Membrane Glycoproteins|Celsr3 protein, mouse|Receptors, Cell Surface 78 celsr3 28716607 Semin. Cell Dev. Biol. 2017 10.1016/j.semcdb.2017.07.014 8 1 0 177 Animals|Mice|CELSR2 protein, human|*Cadherin 3|CELSR1 cadherin, human|Cell Polarity|Cell Movement|Wnt Factors|Neurogenesis|Neurons|Signal Transduction|Carrier Proteins|Phenotypes|Celsr1 protein, mouse|Receptors, G-Protein-Coupled|Celsr3 protein, mouse|Receptors, Cell Surface|Celsr2 protein, mouse 78 celsr3 28492670 Food Funct 2017 10.1039/c6fo01848c 2 0 0 177 Animals|Mice|*Galactose|*Euphausiacea|*Oil, Dietary|*Proteomics|*Aging|Malondialdehyde|Glutathione Peroxidase|Superoxide Dismutase|Memory|Oxidative Stress|Morris Water Maze Test|Lipid Peroxidation|*Diet|Antioxidants|*Oils|Brain|Protective Agents|Celsr3 protein, mouse 78 cenpb 29141960 Genome Res. 2017 PMC5741061 10.1101/gr.219709.116 6 0 0 198 Humans|*Centromere|Centromere Protein B|DNA, Satellite|Chromosomal Proteins, Non-Histone|Autoantigens|DNA Sequence|Nondisjunction, Genetic|*Genomics|Trisomy 21|In Situ Hybridization, Fluorescence|Trisomy|DNA|DNA-Binding Proteins|PCR|Epigenesis, Genetic 183 cenpb 28749191 Autoimmunity 2017 10.1080/08916934.2017.1357699 9 1 0 198 Humans|*Autoantibodies|*Sclerosis, Systemic|Autoantigens|Antibodies, Antinuclear|Centromere Protein A|Chromosomal Proteins, Non-Histone 183 cenpb 28704058 J. Proteome Res. 2017 PMC5587144 10.1021/acs.jproteome.7b00448 4 3 0 198 Humans|*Chromatin|Centromere|Centromere Protein B|Centromere Protein A|DNA, Satellite|Chromosomal Proteins, Non-Histone|*Nucleic Acid Hybridization|Kinetochore|Heterochromatin|DNA-Binding Proteins|DNA|Autoantigens|*Mass Spectrometry|In Situ Hybridization, Fluorescence|Cell Line|Polymerase Chain Reaction 183 cenpb 28346356 Cells 2017 PMC5492013 10.3390/cells6020009 3 16 0 198 *Lamin Type A|*Chromatin|*Histones|*Microinjections|Lamin B|Cell Nucleus|Mitosis|Nuclear Proteins|*Protein Binding|*Antibodies|*Binding Site|Chromosomal Proteins, Non-Histone 183 cenpb 28296274 Int J Rheum Dis 2017 10.1111/1756-185X.13060 1 1 0 198 Humans|Thailand|*Sclerosis, Systemic|*Autoantibodies|Scleroderma, Limited|Antibodies, Antinuclear|Scleroderma, Diffuse|Autoantigens|DNA Topoisomerases, Type I 183 cenpb 28259924 Mol Med Rep 2017 10.3892/mmr.2017.6247 0 0 0 198 Child|Humans|*DNA, Satellite|*Chromosomes, Human, Pair 21|*Down Syndrome|Centromere Protein B|Centromere|Chromosomal Proteins, Non-Histone|*Mutations|Autoantigens|Base Sequence|DNA-Binding Proteins|Binding Site|Cell Division|Polymerase Chain Reaction 183 cenpb 28240591 Clin. Exp. Rheumatol. 2017 0 0 0 198 Humans|*Cytomegalovirus|*Sclerosis, Systemic|cytomegalovirus matrix protein 65kDa|*Viral Matrix Proteins|Autoantibodies|Autoantigens|*Phosphoproteins|*Antibody Formation 183 cenpb 28228545 Mol. Biol. Cell 2017 PMC5391189 10.1091/mbc.E16-07-0485 3 12 0 198 *Heterochromatin|*RNA Interference|*Centromere Protein B|*Retroelements|*Binding Protein|*Transposases|Schizosaccharomyces pombe Proteins|Schizosaccharomyces|Centromere|Argonaute Proteins|RNA, Small Interfering|RNA, Fungal|Cell Cycle Proteins|Chromatin Assembly and Disassembly|Chromatin Immunoprecipitation 183 CES1P1 29088749 Oncotarget 2017 PMC5650304 10.18632/oncotarget.17764 16 3 0 5 Humans|*Prognosis|*Signature, Gene Expression|*Stomach Neoplasms|Likelihood Functions|Gene Expression Profiling|Kaplan-Meier Analysis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cluster Analysis 20 CES1P1 28803225 Drug Metab Pers Ther 2017 10.1515/dmpt-2017-0012 0 0 0 5 Humans|*Carboxylesterase B|*Asian|Frequencies, Allele|Genotyping Techniques|Carboxylic Ester Hydrolases|Haplotypes|Genotype|Promoter Regions, Genetic|Polymorphism, Single Nucleotide|*Inactivation, Metabolic|Polymerase Chain Reaction|Pharmacogenomic Testing|Pharmacogenetics|5' Untranslated Region|*Metabolic Clearance Rate 20 CES1P1 28786738 Pharmacogenomics 2017 10.2217/pgs-2017-0052 1 0 0 5 *Pharmacogenetics|*Pharmacogenomic Testing|Genotyping Techniques|Polymorphism, Single Nucleotide|PCR|Carboxylic Ester Hydrolases|DNA 20 CES1P1 28146010 Pharmacogenet. Genomics 2017 10.1097/FPC.0000000000000267 0 0 0 5 Humans|Carboxylesterase B|Carboxylic Ester Hydrolases|Promoter Regions, Genetic|Polymorphism, Single Nucleotide|*Specificity|*Cell Differentiation 20 CFDP1 29107067 Exp. Cell Res. 2017 10.1016/j.yexcr.2017.10.022 1 0 0 43 Humans|Animals|*Zebrafish|*Osteogenesis|Zebrafish Proteins|Embryo, Nonmammalian|Neural Crest|Morphogenesis|Gene Expression Regulation, Developmental|Skull|Morpholinos|Amino Acid Sequence|Gene Knockdown Techniques|Head|CFDP1 protein, human|Phosphoproteins 40 CFDP1 28394258 J. Clin. Invest. 2017 PMC5409098 10.1172/JCI84840 27 0 0 43 Genome-Wide Association Study|*Heart|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genetic Loci|Quantitative Trait, Heritable|Genotype 40 CFDP1 28367969 Sci Rep 2017 PMC5377257 10.1038/srep45022 3 11 0 43 Humans|HeLa Cells|Epigenesis, Genetic|condensin complexes|Adenosine Triphosphatases|DNA-Binding Proteins|Multiprotein Complexes|Chromatin|Chromosome|Transcription Factors|Mitosis|Phosphoproteins|CFDP1 protein, human 40 CHD6 28533432 J. Biol. Chem. 2017 PMC5512084 10.1074/jbc.M117.779470 0 8 0 261 *Chromatin Assembly and Disassembly|*Nucleosomes|DNA Helicase III|CHARGE Syndrome|DNA-Binding Proteins|Transcription Factors|Chromatin|Gene Expression Regulation|DNA|Adenosine Triphosphate|Promoter Regions, Genetic 31 CHD6 28108554 G3 (Bethesda) 2017 PMC5345725 10.1534/g3.116.037069 15 1 0 261 Animals|*RNA, Long Noncoding|*Chickens|*Cell Differentiation|Adipogenesis|*Genome|Adipocytes|Sequence Analysis, RNA|RNA, Messenger|Gene Expression Profiling|Gene Regulatory Networks|*Abdomen|Cells, Cultured 31 CHI3L2 28989002 Mol. Cell. Neurosci. 2017 10.1016/j.mcn.2017.10.001 7 1 0 30 Humans|*Motor Cortex|*Salts|Neurodegenerative Diseases|*Spinal Cord|Amyotrophic Lateral Sclerosis|Motor Neurons|*Sodium Chloride|*Sodium Chloride, Dietary|Chitinases|Microglia|Prognosis|CHI3L1 protein, human|Chitinase-3-Like Protein 1|CHI3L2 protein, human 35 CHI3L2 28404605 Genetics 2017 PMC5499198 10.1534/genetics.116.199323 0 0 0 30 Animals|Humans|*Chitinase|*Proteomics|*Morphogenesis|Drosophila Proteins|Drosophila melanogaster|Gene Expression Regulation, Developmental|Transcription Factors|Signal Transduction|Protein Binding 35 CHRFAM7A 28978081 Oncotarget 2017 PMC5620221 10.18632/oncotarget.18948 9 3 0 87 Humans|*Nicotinic Acetylcholine Receptor|*Lung Cancers|*Smoking|Nicotine|Carcinoma, Non-Small-Cell Lung|*Lung|alpha7 Nicotinic Acetylcholine Receptor|*Tobacco Smoking|Cell Line, Tumor|Cells, Epithelial 57 CHRFAM7A 31966770 Int J Clin Exp Pathol 2017 PMC6965404 0 0 0 87 Humans|Mice|Animals|*Lacrimal Apparatus|Leukocytes, Mononuclear|*MAP Kinase Signaling System|*Oxidative Stress|Dry Eye|Tears|JNK Mitogen-Activated Protein Kinases|Phosphorylation|AKT1 protein, human|Protein Kinase B|*Radiation Injury|Inflammation|Signal Transduction|Downregulation 57 CILP2 29084944 Sci Rep 2017 PMC5662763 10.1038/s41598-017-13099-4 14 11 0 28 Child, Preschool|Humans|Child|*Pediatric Obesity|*B-DNA|*Epigenome|Epigenetic|DNA Methylation|CpG Islands|Epigenesis, Genetic|Body Mass Index|*Body Composition|Adiposity|Genome-Wide Association Study|Genes, Regulator|DNA|Europe|CYTH4 protein, human|Cell Adhesion Molecules|Guanine Nucleotide Exchange Factors|POC1A protein, human 34 CILP2 28379035 Physiol Res 2017 10.33549/physiolres.933580 2 0 0 28 Humans|Male|Female|*Genome-Wide Association Study|*Hypercholesterolemia|PCSK9 protein, human|Proprotein Convertase 9|Czech Republic|LDL Cholesterol|SNPs|Cholesterol, HDL|Genetic Predisposition to Disease|Dyslipidemia|Triglycerides 34 CIZ1 29285191 Oncol Lett 2017 PMC5738676 10.3892/ol.2017.7282 3 25 0 143 Humans|*Cell Cycle Proteins|Nuclear Protein|DNA Replication|Cell Proliferation|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|Amino Acid Sequence|Zinc Fingers|*Carcinoma, Squamous Cell|*Biomarkers|Ciz1 protein, human|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21 70 CIZ1 29154038 Neurobiol. Aging 2017 PMC5877805 10.1016/j.neurobiolaging.2017.10.014 5 3 0 143 Animals|Mice|*B-DNA|*Mice, Knockout|*Cell Cycle Proteins|DNA Replication|Nuclear Proteins|DNA Repair|Cell Cycle|Neurodegenerative Disorders|Cell Cycle Checkpoints|*Phenotypes|Fibroblasts|DNA Damage|Ciz1 protein, mouse 70 CIZ1 28923964 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5635913 10.1073/pnas.1711206114 18 0 0 143 Female|Animals|*RNA, Long Noncoding|Proteomics|*X Chromosomes|X Chromosome Inactivation|CDKN1A protein, human|*CDKN1A Protein|Dosage Compensation, Genetic|Embryonic Stem Cells|Gene Silencing|Exon|Cell Differentiation|Cell Nucleus|Epigenesis, Genetic 70 CIZ1 28546514 Genes Dev. 2017 PMC5458755 10.1101/gad.295907.117 23 0 0 143 Female|Humans|Child|Mice|Animals|*X Chromosome|X-Inactivation|*RNA, Long Noncoding|Embryonic Stem Cells|*Cell Cycle Proteins|Gene Silencing|Cell Differentiation|Nuclear Matrix|Ciz1 protein, human|Nuclear Proteins|Ciz1 protein, mouse 70 CKAP2 29281706 PLoS ONE 2017 PMC5744973 10.1371/journal.pone.0189955 2 1 0 245 Animals|Female|Humans|*Chickens|*Genome-Wide Association Study|Quantitative Trait Loci|Quantitative Trait, Heritable|SNPs|Phenotype|Crosses, Genetic|*Reproduction|Body Weight|Breeding, Selective|Oviduct 50 CKAP2 28933561 DNA Cell Biol. 2017 10.1089/dna.2017.3876 0 4 0 245 Humans|Female|Mice|Animals|*Focal Adhesion Kinase|*MAP Kinase Signaling System|Matrix Metalloproteinase 2|PTK2 protein, human|*Focal Adhesion Kinase 1|*Carcinoma, Ovarian Epithelial|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|*Ovarian Cancer|Cell Proliferation|*Cytoskeletal Proteins|Mitogen-Activated Protein Kinase 3|Signal Pathway|*Oncogenesis|Cell Movement|Phosphorylation|Apoptosis|Cell Line, Tumor 50 CKAP2 28771517 PLoS ONE 2017 PMC5542386 10.1371/journal.pone.0182107 4 0 0 245 Humans|*Prognosis|Receptor, ErbB-2|Ki-67 Antigen|Receptors, Progesterone|Receptors, Estrogen|Disease-Free Survival|Biomarkers, Tumor|Immunohistochemistry|Kaplan-Meier Estimate|*Cytoskeleton|CKAP2 protein, human|Cytoskeletal Proteins 50 CKAP2 28706298 Exp. Mol. Med. 2017 PMC5565958 10.1038/emm.2017.92 2 10 0 245 Mice|Animals|*Phosphorylation|*CDC2 Protein Kinase|*Centrosome|Cyclin B1|Mitosis|Spindle Apparatus|Chromosome Segregation|Cytoskeletal Proteins 50 CKAP2 28522860 Sci Rep 2017 PMC5437009 10.1038/s41598-017-01832-y 2 37 0 245 Female|Humans|MAPK1 protein, human|*Mitogen-Activated Protein Kinase 1|*Signal Transduction|*Cell Movement|*Cytoskeletal Proteins|*Cervical Cancer|Cell Proliferation|Focal Adhesion Protein-Tyrosine Kinases|Phosphorylation|*MAP Kinase Signaling System|CDH1 protein, human|E Cadherin|Cell Line, Tumor|Tumorigenesis|Cervix|Antigens, CD|CKAP2 protein, human 50 CKAP2 28367986 Sci Rep 2017 PMC5377258 10.1038/srep45200 18 2 0 245 Animals|Humans|*Grasshopper|Chromosomes, Insect|*Chromosomes B|KIF20A protein, human|Kinesin 50 CKAP2 28350120 Oncol. Rep. 2017 10.3892/or.2017.5534 6 4 0 245 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Drug Resistance, Neoplasm|Gene Expression Profiling|Taxol|Bioinformatics|Mutations 50 CLEC11A 29182448 Immunol. Invest. 2017 10.1080/08820139.2017.1405978 4 0 0 80 Humans|*Polyradiculoneuropathy, Chronic Inflammatory Demyelinating|*Multiple Sclerosis|Guillain-Barre Syndrome|Central Nervous System|Neurologic Disorders|Biomarkers|Cytokines 32 CLEC11A 28858830 Environ. Health Perspect. 2017 PMC5783669 10.1289/EHP1246 10 3 0 80 Pregnancy|Humans|Female|*Lead|Maternal Exposure|DNA Methylation|CpG Islands|Prenatal Exposure Delayed Effects|Epigenesis, Genetic|Fetal Blood|Genome-Wide Association Study 32 CLEC11A 28642592 Leukemia 2017 10.1038/leu.2017.197 14 0 0 80 Humans|*Multiple Myeloma|*Disease Progression|Bone Marrow|Prognosis|Genomics|Biomarkers, Tumor|Gene Expression Profiling|High-Throughput Nucleotide Sequencing|Gene Expression Regulation, Neoplastic 32 CLIC5 28779175 Nat Commun 2017 PMC5544706 10.1038/s41467-017-00227-x 33 77 0 111 Humans|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|Caspase 1|CARD Signaling Adaptor Proteins|Interleukin-1beta|Reactive Oxygen Species|*Chlorides|Mitochondria|Potassium|Signal Transduction|Carrier Proteins|Macrophages|Immunity, Innate|Chloride Channels|NLRP3 protein, human|NEK7 protein, human|NIMA-Related Kinases 55 CLIC5 28226404 Am. J. Transplant. 2017 PMC5550741 10.1111/ajt.14233 3 1 0 111 *Kidney Transplantation|Graft Rejection|Graft Survival|*Biopsies|Kidney Failure, Chronic|Kidney Function Tests|*Transplant|Prospective Studies|Oligonucleotide Array Sequence Analysis|Glomerular Filtration Rate|Kidney Diseases|*Nephrectomy|T-Lymphocytes|Gene Expression Profiling|Prognosis|Antibodies 55 CLMN 28097321 JAMA Psychiatry 2017 10.1001/jamapsychiatry.2016.3798 32 0 0 48 *Exome|*Whole Exome Sequencing|Genes, Recessive|*Neurodevelopmental Disorders|Pedigree|Homozygote|Intellectual Disability|Sequence Analysis, DNA|Mutation|Family 29 CLMP 28722448 ACS Sens 2017 10.1021/acssensors.6b00617 1 0 0 63 Raman Scattering|Silver|Gold|Metal Nanoparticles 584 CLMP 28381574 J. Virol. 2017 PMC5446653 10.1128/JVI.02487-16 3 39 0 63 Humans|Mice|Animals|*Adenoviruses, Human|adenovirus receptor|*Serogroup|*Receptors, Virus|Factor X|Transduction, Genetic|*Coxsackievirus Infections|Genetic Vectors|Coxsackie and Adenovirus Receptor-Like Membrane Protein|Gene Transfer Techniques|Capsid Proteins|Virion|Liver|Protein Binding 584 CLMP 28215070 J. Agric. Food Chem. 2017 10.1021/acs.jafc.6b05372 1 0 0 63 *Lipase|Kinetics|Enzyme Stability|Enzymes, Immobilized|*Solvents|Candida|Fungal Proteins|Hydrogen-Ion Concentration|Nanoparticles|Polymers 584 CLMP 28074864 Sci Rep 2017 PMC5225458 10.1038/srep40400 2 7 0 63 Humans|Male|adenovirus receptor|Antibody-Dependent Cell Cytotoxicity|*Receptors, Virus|Antibodies, Monoclonal|Xenograft Model Antitumor Assays|Cell Line, Tumor|Prostate Cancer|Prostate|Immunotherapy|Cell Proliferation|*Antibodies, Viral|*Immunoglobulin Isotypes 584 CLSTN2 28912692 Front Neuroanat 2017 PMC5582071 10.3389/fnana.2017.00076 2 1 0 215 Chick Embryo|Humans|Animals|Mice|*Neurogenesis|Motoneurons|Axons|Ganglia, Spinal|Spinal Cord|Brain|Kinesin 32 CLSTN2 28647593 Behav. Brain Res. 2017 10.1016/j.bbr.2017.06.029 2 0 0 215 Male|Female|Mice|Animals|*Mice, Knockout|*Emotions|Social Behavior|Exploratory Behavior|Maze Learning|Anxiety|calsyntenin-2, mouse|Membrane Proteins|Motor Activity|Calcium-Binding Proteins|Behavior, Animal|Recognition, Psychology|Autism|Cognition|Memory, Spatial|Swimming|Interpersonal Relations|Phenotype 32 CLSTN2 28600779 Hum. Genet. 2017 PMC5502059 10.1007/s00439-017-1821-8 39 1 0 215 Humans|*Exome|Saudi Arabia|Nerve Tissue Proteins|Endoplasmic Reticulum|Golgi Apparatus|Receptors, Immunologic|Vesicular Transport Proteins|Sequencing, Whole Exome|Genes, Recessive|Homozygote|Mutations|Sequencing, Next-Generation|Sequence Analysis, DNA|Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|GRSF1 protein, human 32 CMPK2 28393889 Sci Rep 2017 PMC5385538 10.1038/srep46203 6 6 0 29 Swine|Animals|*Porcine respiratory and reproductive syndrome virus|Porcine Reproductive and Respiratory Syndrome|Genotype|*Gene Expression|Phenotypes|Viremia|Genome-Wide Association Study|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Viral Load|Gain, Weight|Host-Pathogen Interactions|*Immune System Phenomena 21 CNDP1 29027595 J. Inherit. Metab. Dis. 2017 10.1007/s10545-017-0099-2 3 1 0 125 Humans|Female|Child|dipeptidase|Homocarnosinosis|aminoacyl-histidine dipeptidase|*Dipeptidases|Diabetes Mellitus, Type 2|*Amino Acid Metabolism, Inborn Errors|*Brain Diseases, Metabolic, Inborn|Diabetic Nephropathy|Anserine|homocarnosine|Carnosine|Kidney|Dipeptides|Polymorphism, Genetic|Mutations|CNDP1 protein, human 70 CNN3 29151265 FEBS J. 2017 10.1111/febs.14338 5 0 0 296 Pregnancy|Animals|Female|calponin|*Neural Tube|*Neurulation|*Microfilament Proteins|*Calcium-Binding Proteins|CTNNB1 protein, human|beta Catenin|*Neurons|Cell Differentiation|Neural Stem Cells|Signal Transduction|Actin|Neural Tube Defects|Neurogenesis|Embryonic Stem Cells|Gene Expression Regulation, Developmental 39 CNN3 29087046 Proteomics 2017 10.1002/pmic.201700296 1 1 0 296 Animals|Mice|*Proteomics|*Prions|Scrapie|*Brain|Transmissible Spongiform Encephalopathies|Alzheimer Disease|*Biomarkers|Disease Models, Animal|Glial Fibrillary Acidic Protein|Proteome 39 CNPY2 29135454 Aging (Albany NY) 2017 PMC5723690 10.18632/aging.101324 4 2 0 91 Humans|*Colorectal Cancer|*Prognosis|Immunohistochemistry|Kaplan-Meier Estimate|Biomarkers, Tumor|*Protein Isoforms|Gene Expression Regulation, Neoplastic|Proportional Hazards Models|Adaptor Proteins, Signal Transducing|Lymphatic Metastasis|*Colonic Neoplasms|Quantitative Real Time Polymerase Chain Reaction|Tumor Cell Lines|Disease Progression|CNPY2 protein, human 27 CNPY2 29037440 J. Autoimmun. 2017 10.1016/j.jaut.2017.10.002 1 0 0 91 *HLA-B|*Genetic Loci|*Myasthenia Gravis|*Genes, MHC Class I|Genetic Predisposition to Disease|Gene Frequency|Allele|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genotype 27 CNPY2 28869608 Nat. Struct. Mol. Biol. 2017 PMC6102046 10.1038/nsmb.3458 10 34 0 91 Mice|Animals|*Protein C|*Unfolded Protein Response|DDIT3 protein, human|Homologous Protein, C-EBP|Endoplasmic Reticulum Stress|eIF-2 Kinase|Activating Transcription Factor 6|Endoplasmic Reticulum|Signal Transduction|Protein-Serine-Threonine Kinases|Apoptosis|Heat-Shock Proteins|Cell Survival|Transcription Factor|Membrane Proteins|Gene Expression Regulation|Upregulation 27 CNPY2 28603065 Hum. Pathol. 2017 10.1016/j.humpath.2017.06.003 5 9 0 91 Humans|*Esophageal Squamous Cell Carcinoma|*Prognosis|ezrin|*Esophageal Neoplasms|*Decision Trees|Neoplasm Recurrence, Local|*Cytoskeletal Proteins|Carcinoma, Squamous Cell|Disease-Free Survival|Kaplan-Meier Estimate|Immunohistochemistry|Biomarkers, Tumor|Proportional Hazards Models|Tissue Array Analysis|Cell Line, Tumor|PDIA3 protein, human|Protein Disulfide-Isomerases|STMN1 protein, human 27 CNPY2 28235487 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.02.095 5 5 0 91 Humans|*Carcinoma, Renal Cell|TP53 protein, human|*Tumor Suppressor Protein p53|Cancer, Kidney|Genes, Tumor Suppressor|Cell Proliferation|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|p53 Gene|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Cycle|Apoptosis|Cell Movement|Adaptor Proteins, Signal Transducing|Cell Line, Tumor|Promoter Regions, Genetic|CNPY2 protein, human 27 CNPY2 28212443 PLoS ONE 2017 PMC5315303 10.1371/journal.pone.0171265 3 4 0 91 Humans|*Carcinoma, Acinar Cell|In Situ Hybridization, Fluorescence|*Cancer, Salivary Gland|Gene Fusion|Translocation, Genetic|Oncogene Proteins, Fusion|*Transcription Factors|*Genes, Regulator|Biomarkers, Tumor|Diagnosis, Differential|DNA|ZNF217 protein, human|Trans-Activators 27 COBLL1 29122990 Haematologica 2017 PMC5792276 10.3324/haematol.2017.178699 0 11 0 74 Immunoglobulin Variable Region|Immunoglobulin Heavy Chains|Leukemia, Lymphocytic, Chronic, B-Cell|Genes, Immunoglobulin Heavy Chain|Tyrosine Kinase, ROR1|Mutation|Wnt Signaling Pathway|Up-Regulation 29 COBLL1 28419997 Neuroendocrinology 2017 10.1159/000475713 2 1 0 74 *Alzheimer Disease|*Mendelian Randomization Analysis|*Leptin|leptin receptor, human|Receptor, Leptin|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Risk Factors 29 COBLL1 28397868 Leukemia 2017 10.1038/leu.2017.107 1 0 0 74 *Leukemia, Myelogenous, Chronic, BCR-ABL Positive|*Transformation, Blast|*Drug Resistance 29 COBLL1 28258026 Diabetes Res. Clin. Pract. 2017 10.1016/j.diabres.2017.02.013 1 0 0 74 Humans|*Diabetes Mellitus, Type 2|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Alleles|Genotype|Case-Control Studies|Logistic Models 29 COBLL1 28232743 Leukemia 2017 10.1038/leu.2017.72 7 2 0 74 Humans|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|Blast Crisis|4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide|Pyrimidines|Imatinib Mesylate|Protein Kinase Inhibitors|Piperazines|Benzamides|Drug Resistance, Neoplasm|Gene Expression Regulation, Leukemic|Apoptosis|*Transformation, Blast|Cell Line, Tumor 29 COBLL1 28187715 Genet. Sel. Evol. 2017 PMC5301402 10.1186/s12711-017-0296-3 4 0 0 74 Pregnancy|Female|Sheep|Animals|Genome-Wide Association Study|*Breeding|*Genome|Wool|Genotype|Sheep, Domestic|Litter Size|*Genomics|Phenotype|BMPR1B protein, human|Bone Morphogenetic Protein Receptors, Type I|Polymorphism, Single Nucleotide|Mutation|Israel 29 cornulin 28451818 Int. J. Legal Med. 2017 10.1007/s00414-017-1587-5 1 0 0 53 Female|*Nails|Dermatoglyphics|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Chromatography, Liquid|Forensic Sciences|Volatilization|*Finger|Powders|Body Fluids|Cyanoacrylates|Touch|Biomarkers 27 cornulin 28219068 Int. Arch. Allergy Immunol. 2017 10.1159/000453452 6 0 0 53 Humans|*Dermatitis, Atopic|Intermediate Filament Proteins|*Eczema|Skin|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Immunoglobulin E 27 cornulin 28104354 J. Allergy Clin. Immunol. 2017 PMC5513800 10.1016/j.jaci.2016.11.042 19 7 0 53 Humans|*Eosinophilic Esophagitis|*Esophagus|*Cell Differentiation|Interleukin-13|Epithelial Cells 27 COX6A2 29042943 Exp Ther Med 2017 PMC5639384 10.3892/etm.2017.4964 0 22 0 26 *Myocytes, Cardiac|*Protective Agents|*Mitochondria|Traditional Chinese Medicine|Signal Transduction|Drugs, Chinese Herbal|Myocardial Ischemia|*Gene Expression|isoborneol|Camphanes|*Ischemia|*Biochemical Phenomena 24 COX6A2 29020939 BMC Genomics 2017 PMC5637328 10.1186/s12864-017-4148-x 3 7 0 26 Animals|*Sea Bream|*Transcriptome|*Oxidative Phosphorylation|*Diet|*Starvation|Gene Expression Profiling|*Genes, Mitochondrial|Nutritional Status|Muscle, Skeletal|cDNA Libraries|Liver 24 COX6A2 28942281 EBioMedicine 2017 PMC5652136 10.1016/j.ebiom.2017.09.022 3 30 0 26 Humans|Induced Pluripotent Stem Cells|*Mitochondria|Cardiomyocytes|*Hypoxia|Mitochondrial Membranes|Cell Hypoxia|Cardiotonic Agents|Adenosine Triphosphate|Apoptosis|Cells, Cultured 24 COX7A1 28481288 Int J Mol Sci 2017 PMC5454915 10.3390/ijms18051002 7 6 0 25 Animals|Mice|*Rosiglitazone|disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate|Dioxoles|White Adipocyte|*Thermogenesis|Adipocytes, Brown|*Adiposity|Uncoupling Protein 1|Adipose Tissue, White|*Obesity|*Gene Expression|Adipogenesis|PPAR gamma|Cell Differentiation|Gene Expression Regulation|Hypoglycemic Agents|Mitochondrial Proteins|*Cells, Stromal 55 COX7A1 28257939 Res. Vet. Sci. 2017 10.1016/j.rvsc.2017.02.021 2 0 0 25 Humans|Cattle|Animals|*Adipocytes, Brown|*Transcriptome|*Reverse Transcriptase Polymerase Chain Reaction|UCP1 protein, human|Uncoupling Protein 1|Adipose Tissue, White|Adipose Tissue, Brown|Thermogenesis|Gene Expression Regulation|Cell Differentiation 55 CPA4 28596382 J. Biol. Chem. 2017 PMC5535023 10.1074/jbc.M117.776260 8 0 0 103 Mice|Animals|*RNA, Long Noncoding|*Carcinoma, Squamous Cell|*Skin Neoplasms|*Downregulation|*Cell Differentiation|Gene Expression Regulation, Neoplastic|Keratinocyte|Cell Movement|Cell Proliferation|Cell Line, Tumor|Gene Expression Profiling|RNA, Messenger|Signal Transduction 37 CPA4 28475748 Dis. Esophagus 2017 10.1093/dote/dox011 2 0 0 103 Humans|*Esophageal Squamous Cell Carcinoma|*Prognosis|*Esophageal Neoplasms|*Aldehyde Dehydrogenase|Neoplasm Recurrence, Local|Carcinoma, Squamous Cell|Lymphatic Metastasis|Kaplan-Meier Analysis|TNM Classification|Cancer Stem Cell|Immunohistochemistry|Biomarkers, Tumor|Cell Line, Tumor|*Carboxypeptidases|Tissues, Epithelial|ALDH1A1 protein, human 37 CPA4 28209092 Growth Factors 2017 10.1080/08977194.2017.1285764 6 1 0 103 Humans|*Adipogenesis|*Fibroblast Growth Factor 1|*Down-Regulation|*Insulin Resistance|Adipocytes|Cell Differentiation|Adipose Tissue|BAMBI protein, human|Membrane Proteins|Gene Knockdown Techniques|Signal Transduction|Cells, Cultured|Carboxypeptidases 37 CPA4 28123604 J Cancer 2017 PMC5264046 10.7150/jca.17060 4 5 0 103 Humans|*Liver Cancer|Carcinoma, Hepatocellular|*Carboxypeptidases|Cancer Stem Cells|Thy-1 Antigens|Biomarkers, Tumor|Kaplan-Meier Analysis|Disease Progression|Liver Cirrhosis|Liver|Hepatocytes|Tumor Microenvironment 37 CPEB2 29141213 Cell Rep 2017 10.1016/j.celrep.2017.10.073 5 1 0 109 Animals|Mice|*Receptors, AMPA|*Long-Term Potentiation|*Memory|Synaptic Plasticity|Hippocampus|Synapses|Morris Water Maze Test|CPEB2 protein, mouse|RNA-Binding Proteins|Neurons|Carrier Proteins|Mice, Knockout|mRNA 40 CPEB2 28904175 J. Biol. Chem. 2017 PMC5663888 10.1074/jbc.M117.810127 3 3 0 109 *Polyadenylation|Twist-Related Protein 1|*RNA Splicing|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Anoikis|Alternative Splicing|Nuclear Proteins|MicroRNAs|Cell Movement|Cell Line, Tumor|Binding Sites|*Cytosol|Exon 40 CPEB2 28460469 Oncotarget 2017 PMC5432302 10.18632/oncotarget.15844 14 24 0 109 Humans|*Colorectal Cancer|MicroRNAs|Epithelial-Mesenchymal Transition|TWIST1 protein, human|Twist-Related Protein 1|Cell Movement|Gene Expression Regulation, Neoplastic|3' Untranslated Region|Liver Neoplasms|HCT116 Cells|RNA Interference|Cell Proliferation|Nuclear Proteins|Cell Line, Tumor|Xenograft Model Antitumor Assays|*Colonic Neoplasms|Up-Regulation|CPEB2 protein, human 40 CPEB2 28434803 Dev. Biol. 2017 PMC5544531 10.1016/j.ydbio.2017.04.008 5 5 0 109 Male|Female|Animals|*Planarians|Germ Cells|Oogenesis|Spermatogenesis|Testes|RNA Interference|Cell Differentiation|Oocyte|Gene Expression Regulation, Developmental|mRNA|Ovaries|*Reproductive System 40 CPEB2 28358263 Cell Cycle 2017 PMC5405720 10.1080/15384101.2017.1301334 21 2 0 109 *Nasopharyngeal Carcinoma|*RNA, Long Noncoding|*Nasopharynx Cancers|*Paclitaxel|*Nasopharynx|Gene Expression Regulation, Neoplastic|Upregulation|MicroRNAs|Down-Regulation|Cell Proliferation|Cell Line, Tumor|Carcinoma|Apoptosis|Apoptosis Regulatory Proteins|Signal Transduction|mRNA|siRNA 40 CPEB3 28454775 Methods 2017 10.1016/j.ymeth.2017.04.021 4 0 0 216 cyclopropene|*Cyclopropanes|Diels Alder Reaction|RNA|*RNA, Untranslated|Synthesis Methods, Solid-Phase|Staining and Labeling|Fluorescent Dyes|Electron 69 CPEB4 29286212 Cell Biol. Int. 2017 10.1002/cbin.10930 2 12 0 206 *Carcinoma, Non-Small-Cell Lung|*Proto-Oncogene Proteins c-akt|*Lung Neoplasms|Phosphatidylinositol 3-Kinases|*Cell Migration|Neoplasm Invasiveness|Signal Transduction|Snail Family Transcription Factors|siRNA|Epithelial-Mesenchymal Transition|RNA Interference|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one|Chromones|Morpholines 83 CPEB4 29166615 Cell Rep 2017 10.1016/j.celrep.2017.10.100 2 3 0 206 Animals|Mice|*Cell Survival|Olfactory Bulbs|*Smell|*Proto-Oncogene Proteins c-fos|*Neurons|Neurogenesis|Interneurons|*Cytoplasmic Granules|Cyclic AMP Response Element-Binding Protein|*Brain|Signal Transduction|RNA, Messenger|Cpeb4 protein, mouse|RNA-Binding Proteins 83 CPEB4 29098032 Oncol Lett 2017 PMC5652194 10.3892/ol.2017.6845 7 9 0 206 *DNA Copy Number Variations|MIRN92 microRNA, human|*RNA, Micro|MIRN124-3 microRNA, human|*Osteosarcoma|Regulatory Network, Gene|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Downregulation|Upregulation|Gene Expression|Signal Transduction|Software 83 CRELD1 29054759 Gene 2017 10.1016/j.gene.2017.10.044 3 2 0 38 Child|Humans|Atrioventricular Septal Defect|*Down Syndrome|*Heart Septal Defects|Endocardial Cushion Defect|Genetic Predisposition to Disease|Congenital Heart Defects|Extracellular Matrix Proteins|Transcription Factor|Phenotype|Cell Adhesion Molecules|CRELD1 protein, human 32 CRELD1 28591652 Stem Cell Reports 2017 PMC5470234 10.1016/j.stemcr.2017.05.013 2 5 0 38 Humans|Female|Rats|Pregnancy|Animals|*Induced Pluripotent Stem Cells|*Amniotic Fluid|*Meningomyelocele|Cellular Reprogramming|*Therapy, Fetal|*Skin|Cell Differentiation|Keratinocytes|Octamer Transcription Factor-3|Cells, Cultured|Cell Culture Techniques|Epidermal Cells|Epidermis|Fibroblasts 32 CRIP1 29179181 Cell. Physiol. Biochem. 2017 10.1159/000485357 3 2 0 104 Humans|*Cysteine|*Colorectal Cancer|Cell Proliferation|LIM Domain Proteins|Carrier Proteins|Cell Line, Tumor|Cell Movement|RNA, Small Interfering|Apoptosis|*Colonic Neoplasms|CRIP1 protein, human 80 CRIP1 29059670 Cell. Physiol. Biochem. 2017 10.1159/000484184 2 2 0 104 *Cysteine|*Carcinoma, Thyroid|Cell Proliferation|Cell Movement|Cell Line, Tumor|LIM Domain Proteins|Apoptosis|Gene Expression Regulation, Neoplastic|Carrier Proteins|Prognosis 80 CRIP1 28940471 J Mass Spectrom 2017 10.1002/jms.4032 3 0 0 104 Humans|*Chromatography, Liquid|*Tandem Mass Spectrometry|Early Detection of Cancer|*Colorectal Cancers|DNA Methylation|*Exon|Biomarkers, Tumor|Core Binding Factor Alpha 3 Subunit|hydrogen sulfite|Sulfites|*Screening|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Nested Polymerase Chain Reaction|*Colonic Neoplasms 80 CRIP1 28935605 Biochim Biophys Acta Gen Subj 2017 10.1016/j.bbagen.2017.09.006 6 4 0 104 *Pyridoxine|*Serotonin|*Cannabinoid Receptor CB1|*Tyrosine 3-Monooxygenase|Proteomics|*Hippocampus|*Cannabinoids|RIPK1 protein, human|*Receptor-Interacting Protein Serine-Threonine Kinases|Cell Differentiation|*Cognitive Function|Cell Proliferation 80 CRIP1 28784648 Hypertension 2017 PMC5997260 10.1161/HYPERTENSIONAHA.117.09458 8 1 0 104 Humans|*Blood Pressure|*Transcriptome|*Blood Pressure Determination|Hypertension|*Transcriptome Analysis|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Cardiovascular Disease 80 CRIP1 28445428 Int J Mol Sci 2017 PMC5454826 10.3390/ijms18050913 2 1 0 104 *Metallothionein|*Cysteine|Electrospray Ionization Mass Spectrometry|Protein Folding|CRIP1 protein, human|*LIM Domain Proteins|Protein Binding|Kinetics|Metals|Alkylation 80 CRIP1 28138039 FASEB J. 2017 10.1096/fj.201601186 1 0 0 104 Mice|Animals|*Angiotensin II|*Cysteine|Cardiomegaly|Cyclic GMP|Myocytes, Cardiac|Signal Transduction|CRIP1 protein, human|LIM Domain Proteins|Carrier Proteins|Protein Binding 80 CROCC 28625779 Curr. Biol. 2017 PMC5546243 10.1016/j.cub.2017.05.066 0 14 0 82 Mice|Animals|*Cytoskeleton|Nuclear Envelope|*Isoforms|*Cilia|Nucleoskeleton|Membrane Proteins|Cytoskeletal Proteins|Microtubule-Associated Proteins|Nuclear Proteins|Nerve Tissue Proteins|Cell Nucleus|NIH 3T3 Cells|Amino Acid Sequence|Syne1 protein, mouse 32 CROCC 28089774 Biochim Biophys Acta Mol Cell Res 2017 10.1016/j.bbamcr.2017.01.007 4 6 0 82 Humans|VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|*Centrosome|Centrioles|Microtubule-Associated Proteins|Microtubule-Organizing Center|Cytoskeletal Proteins|Interphase|Cell Cycle Proteins|NIMA-Related Kinases|Protein-Serine-Threonine Kinases|Cell Cycle|Ubiquitination|HeLa Cells|CEP68 protein, human 32 CROCC 28059168 Sci Rep 2017 PMC5216331 10.1038/srep39967 0 6 0 82 *Cytoskeleton|Second Harmonic Generation Microscopy|Cilium|Cytoskeletal Proteins|Centrosome|Retinal Photoreceptor|*Specificity|Retina 32 CRTAC1 28935984 Sci Rep 2017 PMC5608707 10.1038/s41598-017-12449-6 0 7 0 35 27 CRTAC1 28880879 PLoS ONE 2017 PMC5589167 10.1371/journal.pone.0184258 4 2 0 35 Mice|Animals|Nogo Receptor 1|*Brain Ischemia|*Neuronal Plasticity|Nogo Proteins|Growth Cones|Axons|Recovery of Function|Stroke|Neurons|Mice, Transgenic|Signal Transduction|Middle Cerebral Artery Occlusion|Calcium-Binding Proteins|Disease Models, Animal|Cells, Cultured 27 CRYBB2 29259299 Sci Rep 2017 PMC5736644 10.1038/s41598-017-18222-z 2 0 0 149 Child|Humans|Cataract, Autosomal Dominant|*Cataract|gamma-Crystallins|beta-Crystallin B Chain|DNA Mutational Analysis|Pedigree|Missense Mutation|Genes, Dominant|Base Sequence|Chinese|Mutations|Amino Acid Sequence|Sequencing, Next-Generation|*Epithelial Cells|Family Members|*Apoptosis 99 CRYBB2 28839118 G3 (Bethesda) 2017 PMC5633377 10.1534/g3.117.300109 5 0 0 149 Child|Humans|*Cataract|*Mutations|gamma-Crystallins|DNA Mutational Analysis|Connexins|Pedigree|Phenotype|Base Sequence|Eye Proteins|Amino Acid Sequence|Asian Continental Ancestry Group|Sequence Alignment|Family Members|Genetic Testing|Australia|South Australia 99 CRYBB2 28546921 Int J Ophthalmol 2017 PMC5437452 10.18240/ijo.2017.05.04 3 1 0 149 Humans|*Frameshift Mutation|Cataract, Autosomal Dominant|*Cataracts|gamma-Crystallins|*Chinese|Pedigree|Genes, Dominant|DNA Mutational Analysis|Base Sequence|Mutation, Missense|Connexins|Mutation 99 CRYBB2 28120589 Acta Med Iran 2017 4 1 0 149 Male|Humans|Female|Iran|beta-Crystallin A Chain|Cataract, Autosomal Dominant|*Cataracts|DNA Mutational Analysis|Crystallin|Genes, Dominant|Pedigree|Mutation|Base Sequence|Asian Continental Ancestry Group|Exon|Heterozygote|CRYBB1 protein, human|beta-Crystallin B Chain|CRYBA1 protein, human|CRYGD protein, human|gamma-Crystallins 99 CRYBB3 28418495 Invest. Ophthalmol. Vis. Sci. 2017 PMC5397132 10.1167/iovs.17-21469 13 1 0 14 Pakistan|*Homozygote|*Cataract|Genes, Recessive|Pedigree|Lod Score|DNA Mutational Analysis|Genetic Linkage|Base Sequence|Haplotypes|Amino Acid Sequence|Mutation 36 CRYGC 29110605 Curr. Mol. Med. 2017 10.2174/1566524017666171101165021 1 3 0 132 *Proteasome Endopeptidase Complex|alpha-Crystallin A Chain|Ubiquitin|Lens, Crystalline|Glutathione|Cataract|Oxidative Stress 65 CRYGC 28546921 Int J Ophthalmol 2017 PMC5437452 10.18240/ijo.2017.05.04 3 1 0 132 Humans|*Frameshift Mutation|Cataract, Autosomal Dominant|*Cataracts|gamma-Crystallins|*Chinese|Pedigree|Genes, Dominant|DNA Mutational Analysis|Base Sequence|Mutation, Missense|Connexins|Mutation 65 CRYGC 28298635 Sci Rep 2017 PMC5428270 10.1038/s41598-017-00318-1 1 0 0 132 Humans|Child|Infant|Cataract, zonular|*Cataract|gamma-Crystallins|*Chinese|Pedigree|DNA Mutational Analysis|Genes, Dominant|Mutations|Haplotypes|Corneal Diseases|Eye Abnormalities|Cohort Studies|China|Crygc protein, human 65 CRYGD 29019065 Mol. Biol. Rep. 2017 10.1007/s11033-017-4130-3 0 0 0 30 Humans|gamma-Crystallins|*Cataract|*Mutation|DNA Mutational Analysis|Pedigree|Mutation, Missense|Asian Continental Ancestry Group|Haplotypes|CRYGD protein, human 154 CRYGD 28849415 Mol. Biol. Rep. 2017 10.1007/s11033-017-4121-4 3 0 0 30 Male|Female|Humans|gamma-Crystallins|Cataract, Autosomal Dominant|*Cataract|*Mutation|DNA Mutational Analysis|Pedigree|Genes, Dominant|Phenotype|Lod Score|Amino Acid Sequence|Mutation, Missense|Base Sequence|Exome|CRYGD protein, human 154 CRYGD 28739408 Int. J. Biol. Macromol. 2017 10.1016/j.ijbiomac.2017.07.120 2 0 0 30 Humans|Orange G|C.I. direct red 80|*Azo Compounds|*Amyloid|gamma-Crystallins|*Amyloidogenic Proteins|Protein Folding|Circular Dichroism|*Amyloidosis|Models, Molecular|Hydrogen-Ion Concentration|Spectrometry, Fluorescence|Hydrophobic and Hydrophilic Interactions 154 CRYZ 28748635 Birth Defects Res 2017 PMC5854563 10.1002/bdr2.1063 6 2 0 488 Humans|*Cleft Lip|*Whole Exome Sequencing|*DNA Copy Number Variations|Cleft Palate|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Genotype|Pedigree|Sequencing, Next-Generation|*Hispanic Americans|Case-Control Studies|*Palate 164 CRYZ 28483414 Lancet Infect Dis 2017 10.1016/S1473-3099(17)30242-6 25 0 0 488 Infant|Humans|Child, Preschool|*Rotavirus Vaccines|*Rotavirus|*Double-Blind Method|South Africa|Rotavirus Infections|*Vaccines, Subunit|Immunization Schedule|Antibodies, Neutralizing|Antibodies, Viral|Vaccines, Attenuated|Immunoglobulin A|Vaccination 164 CSMD2 28332277 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2017 PMC5467442 10.1002/ajmg.b.32527 0 3 0 9 20 CSMD3 29142225 Nat Commun 2017 PMC5688099 10.1038/s41467-017-01730-x 15 1 0 6 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Asian|*European Continental Ancestry Group|Carcinoma, Squamous Cell|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Comparative Genomic Hybridization|Mutations|Mutation Frequencies|Genomics 41 CSMD3 29141020 PLoS ONE 2017 PMC5687749 10.1371/journal.pone.0188272 1 5 0 6 Humans|Epithelial-Mesenchymal Transition|*Cancer, Skin|*Genomics|Mutations|High-Throughput Nucleotide Sequencing|Whole Exome Sequencing|Gene Expression Profiling|Genes, p16|Skin Diseases|Base Sequence|Receptor, ErbB-4|Databases, Genetic|KANK1 protein, human|Tumor Suppressor Proteins 41 CSMD3 28256045 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38204 0 1 0 6 Humans|Trichorhinophalangeal Syndrome, Type I|*Nose|*Intellectual Disability|*Langer-Giedion Syndrome|*Hair Diseases|*Fingers|DNA-Binding Proteins|*Finger Phalanges|Transcription Factors|*Syndrome|Zinc Fingers|Mutations|Frameshift Mutation|Pedigree|Genes, Regulator|Abnormalities, Multiple|TRPS1 protein, human 41 CST7 28904096 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5642727 10.1073/pnas.1714175114 46 4 0 128 Mice|Animals|Humans|*Alzheimer Disease|*Microglia|presenilin 1, mouse|Presenilin-1|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|Mice, Transgenic|Mice, Inbred C57BL|Disease Models, Animal|Cytokines|RIPK1 protein, human|*Receptor-Interacting Protein Serine-Threonine Kinases|Brain|Cells, Cultured|Ripk1 protein, mouse 39 CST7 28630039 J. Biol. Chem. 2017 PMC5582836 10.1074/jbc.M117.776138 3 0 0 128 asparaginylendopeptidase|*Cystatin M|CST3 protein, human|Cystatin C|Protease Inhibitors, Cysteine|Cathepsin B|Melanoma|matrigel|Proteoglycans|Laminin|Cell Line, Tumor|Collagen|Binding Sites|Drug Combinations 39 CST7 28178353 PLoS ONE 2017 PMC5298286 10.1371/journal.pone.0171923 8 3 0 128 Humans|Animals|Mice|*Cystatin B|*Prions|Prion Diseases|Scrapie|Creutzfeldt-Jakob Syndrome|PrPSc Proteins|Prion Protein|Brain|Neurodegenerative Diseases|*Transcription Factors|*Biomarkers 39 CTAGE1 28701399 J. Virol. 2017 PMC5599734 10.1128/JVI.00810-17 2 4 0 3 Humans|*CD8-Positive T-Lymphocytes|CXCR3 protein, human|*Receptors, CXCR3|Herpes Simplex Virus 2|Immunologic Memory|SELE protein, human|E-Selectin|Antigens, Differentiation, T-Lymphocyte|Skin|Lymphocyte Activation|CCL27 protein, human|Chemokine CCL27|Receptors, Lymphocyte Homing|Herpes Simplex Virus 1|Antigens, Neoplasm|CCR10 protein, human|Receptors, CCR10 238 CTAGE1 28601883 Dermatology (Basel) 2017 10.1159/000475546 2 0 0 3 Humans|*Interleukin-13|*Skin|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Antigens, Differentiation, T-Lymphocyte|Receptors, Lymphocyte Homing|*Eosinophilia|Dermatitis, Atopic|Th2 Cells|*Drug Eruptions|Lymphocyte Activation|Antigens, Neoplasm|Membrane Glycoproteins|Flow Cytometry|Exanthema 238 CTAGE1 28392462 Clin. Immunol. 2017 10.1016/j.clim.2017.04.001 6 0 0 3 Humans|*Skin|Psoriasis|CD4-Positive T-Lymphocytes|CD8-Positive T-Lymphocytes|Immunologic Memory|Receptors, CCR4|Antigens, Differentiation, T-Lymphocyte|Antigens, Neoplasm|Membrane Glycoproteins 238 CUZD1 28964710 J Sex Med 2017 10.1016/j.jsxm.2017.09.003 0 0 0 24 Female|Humans|*Twins, Monozygotic|*DNA Methylation|*B-DNA|Epigenetics|Epigenesis, Genetic|Sexual Dysfunctions, Psychological|Phenotype|*Protein Processing, Post-Translational 35 CUZD1 28746862 Clin. Biochem. 2017 10.1016/j.clinbiochem.2017.07.012 1 0 0 24 *Antibodies, Monoclonal|*Immunofluorometric Assay|Crohn Disease|Autoantibodies|Enzyme-Linked Immunosorbent Assay|Biomarkers|Membrane Proteins|*Antineoplastic Agents, Immunological 35 CUZD1 28343172 Clin. Chem. Lab. Med. 2017 10.1515/cclm-2016-1120 2 0 0 24 Humans|*Autoantibodies|Colitis, Ulcerative|Crohn's Disease|Indirect Immunofluorescence Assays|*Inflammatory Bowel Diseases|Immunoglobulin A|GPI-Linked Proteins|Autoantigens|*Immunoassays|Immunoglobulin G|Pancreas|Enzyme-Linked Immunosorbent Assay|Biomarkers|Membrane Proteins|CUZD1 protein, human 35 CUZD1 28278176 PLoS Genet. 2017 PMC5363987 10.1371/journal.pgen.1006654 3 61 0 24 Pregnancy|Mice|Female|Animals|STAT5A protein, human|*STAT5 Transcription Factor|Proteomics|*Signal Transduction|JAK2 protein, human|Janus Kinase 2|Prolactin|Mammary Glands, Animal|*Tumor Suppressor Proteins|Receptors, Prolactin|Lactation|Cell Differentiation|Cells, Epithelial|EGFR protein, human|ErbB Receptors|DNA-Binding Proteins|Mice, Knockout|Epidermal Growth Factor 35 CYP4X1 29227996 PLoS ONE 2017 PMC5724839 10.1371/journal.pone.0187959 0 1 0 8 Male|Female|Animals|Mice|*Knockout Mouse|cytochrome P-450 4X1|*Cytochrome P-450 Enzyme System|Amino Acid Sequence|RNA, Messenger|Diet, High-Fat|RNA|Brain|Oxidation-Reduction 26 CYP4X1 28472114 PLoS ONE 2017 PMC5417718 10.1371/journal.pone.0177014 11 1 0 8 Swine|Animals|*DNA Copy Number Variations|*Sequencing, Whole Genome|*Phenotype|Breeding|Quantitative Trait Loci|Sus scrofa|SNPs|Sequencing, Next-Generation|Genomics|*Fatty Acids|Real-Time Polymerase Chain Reaction 26 CYP4X1 28153492 Drug Metab. Pharmacokinet. 2017 10.1016/j.dmpk.2016.10.409 3 0 0 8 Male|Female|Humans|cytochrome P-450 4X1|Cytochrome P-450 Enzyme System|*Inactivation, Metabolic|*Liver|*Gene Expression|Pregnane X Receptor|Receptors, Steroid|estrone sulfotransferase|Sulfotransferases|Oligonucleotide Array Sequence Analysis|*Metabolic Clearance Rate|CYP3A4|Gene Expression Regulation, Enzymologic|Gene Expression Profiling 26 CYTL1 28671352 J. Orthop. Res. 2017 PMC5752630 10.1002/jor.23644 10 0 0 57 Swine|Animals|*Cartilage, Articular|Anterior Cruciate Ligament|Anterior Cruciate Ligament Reconstruction|Anterior Cruciate Ligament Injuries|Osteoarthritis, Knee|Knee Joint|Swine, Miniature|Synovial Membrane|MMP1 protein, human|Matrix Metalloproteinase 1 34 CYTL1 28478073 Cytokine 2017 PMC5507608 10.1016/j.cyto.2017.04.023 3 16 0 57 Humans|Mice|Animals|Receptor, CCR2|Chemokines|Receptors, Cytokine|Cytokines|Chemokine CCL2|Chondrocytes|Cartilage|Protein Binding|Signal Transduction|Amino Acid Sequence|Homology, Sequence|Models, Molecular|Macrophages|Chemotaxis|*Biophysics|Ligands|CYTL1 protein, human|Blood Proteins 34 DACT2 29199082 Pharmacol. Res. 2017 10.1016/j.phrs.2017.11.032 0 6 0 129 DNA Methylation|Wnt Pathway|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|Carrier Proteins|Promoter Regions, Genetic|Cell Line, Tumor|Tumorigenesis|Epigenesis, Genetic|Downregulation|*Epigenetic|Colonic Neoplasms 53 DACT2 28796248 Cell Death Dis 2017 PMC5596571 10.1038/cddis.2017.385 2 42 0 129 Humans|*Up-Regulation|*Glioma|*Apoptosis|Wnt Signaling Pathway|beta Catenin|Gene Expression Regulation, Neoplastic|Cell Proliferation|Neoplasm Proteins|Cell Line, Tumor|*Transcriptional Activation|Cell Cycle|Carrier Proteins|Cell Movement|Genes, Tumor Suppressor|Promoter Regions, Genetic|DACT2 protein, human 53 DACT2 28607412 Sci Rep 2017 PMC5468316 10.1038/s41598-017-03647-3 5 12 0 129 Humans|Female|Mice|Animals|*Wnt Signaling Pathway|DNA Methylation|Neoplasm Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Carrier Proteins|Azacitidine|Cell Proliferation|Gene Silencing|Xenograft|DACT2 protein, human 53 DACT2 28077137 J. Biomed. Sci. 2017 PMC5225534 10.1186/s12929-016-0308-6 3 8 0 129 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Promoter Regions, Genetic|Epigenesis, Genetic|DNA Methylation|Prognosis|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Azacitidine|Cell Proliferation|Biomarkers, Tumor|Gene Silencing|Cell Line, Tumor|Carrier Proteins|*Neoplastic Processes 53 DAOA 29287327 Food Chem 2017 10.1016/j.foodchem.2017.11.061 0 0 0 34 Olive Oil|Olea|Fruit|Saturated Fatty Acids|Phenols|Food Quality|Taste|Italy 168 DAOA 29114206 Front Mol Neurosci 2017 PMC5660716 10.3389/fnmol.2017.00342 3 18 0 34 Humans|*D-Aspartic Acid|*N-Methylaspartate|*Astrocytes|DAO protein, human|*D-Amino-Acid Oxidase|*Receptors, N-Methyl-D-Aspartate|Genetic Predisposition to Disease|Schizophrenia|Polymorphism, Single Nucleotide|Intracellular Signaling Peptides and Proteins|Genotype|*Cell Lines|Case-Control Studies|DAOA protein, human|Carrier Proteins 168 DAOA 29100974 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.10.017 2 1 0 34 Humans|*Asian Continental Ancestry Group|*Schizophrenia|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Study, Genetic Association|Genotype|Nerve Tissue Proteins|Carrier Proteins|NOS1 protein, human|*Nitric Oxide Synthase Type I|Case-Control Studies|Adaptor Proteins, Signal Transducing|DAOA protein, human|DISC1 protein, human|NOS1AP protein, human|GSK3B protein, human|Glycogen Synthase Kinase 3 beta 168 DAOA 28989979 Wellcome Open Res 2017 PMC5605947 10.12688/wellcomeopenres.12171.1 1 0 0 34 *Haplotypes|*Longitudinal Studies|United Kingdom|*Biological Specimen Banks|Multifactorial Inheritance|Genome-Wide Association Study|Genetic Predisposition to Disease|Scotland|Polymorphism, Single Nucleotide|Genotype|Depressive Disorder, Major|Cognition 168 DAOA 28864885 J Neural Transm (Vienna) 2017 10.1007/s00702-017-1782-z 7 1 0 34 Humans|NRG1 protein, human|*Neuregulin-1|DAO protein, human|*D-Amino-Acid Oxidase|*Schizophrenia|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Haplotypes|Gene Frequency|Genotype|Carrier Proteins|Asian|Allele|Case-Control Studies|Intracellular Signaling Peptides and Proteins|Amino Acids|DAOA protein, human 168 DAOA 28477547 Psychiatry Res 2017 10.1016/j.psychres.2017.04.060 0 0 0 34 Humans|*Depressive Disorder, Major|*Schizophrenia|Psychiatric Status Rating Scales|Glutamate|*Plasma|Serine|Neurotransmission|DAO protein, human|D-Amino-Acid Oxidase 168 DAOA 28428746 Front Neuroanat 2017 PMC5382383 10.3389/fnana.2017.00031 12 2 0 34 DAO protein, human|*D-Amino-Acid Oxidase|Schizophrenia|Polymorphism, Single Nucleotide|Carrier Proteins|Brain|Intracellular Signaling Peptides and Proteins|Serine|Case-Control Studies 168 DAOA 28285246 Psychiatry Res 2017 10.1016/j.psychres.2017.03.013 2 1 0 34 Humans|DAO protein, human|D-Amino-Acid Oxidase|*Schizophrenia|Haplotype|SNPs|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Gene Frequency|Genotype|Epistasis, Genetic|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Case-Control Studies|DAOA protein, human 168 DAOA 28207827 PLoS ONE 2017 PMC5313182 10.1371/journal.pone.0172365 3 0 0 34 *Polymorphism, Single Nucleotide|*Keratoconus|Czech Republic|Genetic Predisposition to Disease|Genetic Association Studies|*Cohort Studies|Genome-Wide Association Study|Cornea|Genotype 168 DAOA 28197415 Biomed Res Int 2017 PMC5288522 10.1155/2017/5925714 3 1 0 34 *Schizophrenia|*Isoforms|D-Amino-Acid Oxidase|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies 168 DAOA 28166363 FEBS Lett. 2017 10.1002/1873-3468.12585 4 1 0 34 Humans|D-Amino-Acid Oxidase|*Schizophrenia|Serine|Intracellular Signaling Peptides and Proteins|Protein Binding|N Methyl D Aspartate Receptors|Protein Conformation|Ligands|Brain|Flavin-Adenine Dinucleotide|Cell Line, Tumor 168 DAZ1 28521575 Hum Fertil (Camb) 2017 10.1080/14647273.2017.1322718 0 0 0 63 Humans|Male|Semen Analysis|In Situ Hybridization, Fluorescence|Male sterility due to Y-chromosome deletions|*Infertility, Male|Deleted in Azoospermia 1 Protein|Oligospermia|Sex Chromosome Disorders of Sex Development|Sex Chromosome Aberrations|Azoospermia|Chromosome Deletion|Primed In Situ Labeling|Chromosomes, Human, Y|Sperm|Spermatogenesis|*Cell Nucleus|Polymerase Chain Reaction|*Genome Instability 205 DBR1 28931690 J. Virol. 2017 PMC5686728 10.1128/JVI.01377-17 4 0 0 69 *HIV-1|RNA Nucleotidyltransferases|RNA Splicing|RNA, Fungal|RNA Precursors|Introns|cDNA|Saccharomyces cerevisiae|Amino Acid Sequence|*HIV Seropositivity|shRNA 63 DBR1 28504715 Oncogene 2017 PMC5608638 10.1038/onc.2017.150 6 10 0 69 Humans|*Alternative Splicing|*Ribonucleoproteins, Small Nuclear|RNA Splicing|RNA Precursors|Spliceosomes|Exon|Introns|RNA|RNA, Messenger|Cell Line, Tumor|Cell Transformation, Neoplastic|Dbr1 protein, human|RNA Nucleotidyltransferases 63 DBR1 28504306 FEBS Lett. 2017 PMC5733776 10.1002/1873-3468.12677 2 1 0 69 lariat debranching enzyme|*RNA|*Entamoeba histolytica|*RNA Nucleotidyltransferases|Introns|*Catalysis|Zinc 63 DBR1 28055181 ACS Chem. Biol. 2017 10.1021/acschembio.6b00971 1 0 0 69 *Kinetics|*RNA|RNA Nucleotidyltransferases|Intron|RNA Splicing|phosphoramidic acid|Phosphoric Acids|Amides 63 DBR1 28053119 Nucleic Acids Res. 2017 PMC5416886 10.1093/nar/gkw1341 6 11 0 69 Humans|*Introns|MicroRNAs|RNA-Binding Proteins|DICER1 protein, human|Ribonuclease III|*RNA, Untranslated|RNA Splicing|RNA Precursors|AGO2 protein, human|Argonaute Proteins|Alternative Splicing|RNA, Messenger|steroid receptor RNA activator|RNA, Long Noncoding|DEAD-box RNA Helicases 63 DCHS1 29229672 Genome Res. 2017 PMC5793789 10.1101/gr.206938.116 1 0 0 39 Animals|*DNA Copy Number Variations|Smegmamorpha|Selection, Genetic|Adaptation, Physiological|Genetic Variation|Biological Evolution|Phenotype|Fresh Water|Base Sequence|Acclimatization|Polymorphism, Single Nucleotide|Ecosystem|Seawater 40 DCHS1 29224215 Mol Genet Genomic Med 2017 PMC5823682 10.1002/mgg3.347 2 0 0 39 Humans|*Mitral Valve Prolapse|Mitral Regurgitation|Mitral Valve|Echocardiography|Genetic Predisposition to Disease|DCHS1 protein, human|Cadherins 40 DCHS1 29165578 J. Clin. Endocrinol. Metab. 2017 10.1210/jc.2017-01660 6 0 0 39 Humans|*Multifactorial Inheritance|*Exome|*Pituitary Diseases|Pituitary Stalk|Hypopituitarism|*Whole Exome Sequencing|*Syndrome|Pituitary Gland, Anterior|Genetic Predisposition to Disease|Mutation 40 DCHS1 29046692 Int J Pediatr Endocrinol 2017 PMC5640965 10.1186/s13633-017-0052-z 1 5 0 39 Humans|Female|Van Maldergem Wetzburger Verloes syndrome|*Hand Deformities, Congenital|*Foot Deformities, Congenital|*Craniofacial Abnormalities|*Abnormalities, Multiple|*Intellectual Disability|*Joint Instability|*Hypogonadism|*Klinefelter Syndrome|Phenotype|*Endocrine System Diseases|Pedigree 40 DCHS1 28705793 Arterioscler. Thromb. Vasc. Biol. 2017 10.1161/ATVBAHA.117.309818 6 0 0 39 *Lymphatic Vessels|*Endothelial Cell|Lymphangiogenesis|*Signal Transduction|*Morphogenesis|Endothelium, Lymphatic|Vascular Endothelial Growth Factor C|Lymphedema|Tumor Suppressor Proteins 40 dd3 29251812 J. Thromb. Haemost. 2017 PMC5826847 10.1111/jth.13927 6 7 0 474 Mice|Animals|*von Willebrand Factor|*Platelet Adhesiveness|Platelet Glycoprotein GPIb-IX Complex|Platelet|Protein Binding 125 dd3 28647161 Int. J. Drug Policy 2017 10.1016/j.drugpo.2017.05.042 7 0 0 474 Antiviral Agents|*Pharmacies|*Feasibility Studies|Hepatitis C, Chronic|*Hepatitis C Antibodies|Therapy, Opioid Substitution|Hepatitis C|Ribavirin|Interferon-alpha|Substance Abuse, Intravenous|*Analgesics, Opioid|Polyethylene Glycols 125 dd3 28526000 BMC Cancer 2017 PMC5438552 10.1186/s12885-017-3344-z 11 0 0 474 Humans|*Smoking Cessation|Quality of Life|*Cancer|Smoking|*Qualitative Research|Family Members|Cancer Survivors|Health Personnel 125 dd3 28054368 Br J Clin Pharmacol 2017 PMC5427234 10.1111/bcp.13205 5 1 0 474 *Cohort Studies|Histamine H2 Antagonists|*Bacterial Infections|Clostridium difficile|Proton Pump Inhibitors|*Gastroenteritis|Case-Control Studies|Risk Factors|*Research Design|*Diagnostic Tests, Routine 125 DDX25 29288727 Gene 2017 10.1016/j.gene.2017.12.044 3 0 0 41 Male|Animals|*Spermatogonia|*Spermatids|*Spermatogenesis|*Brachyura|Testis|Spermatozoa|Spermatocytes|Arthropod Proteins|Acrosome|Gonads|Cloning, Molecular|*Mitosis|mRNA|Amino Acid Sequence|Cell Nucleus 39 DDX25 28824886 Front Cell Infect Microbiol 2017 PMC5543031 10.3389/fcimb.2017.00356 4 41 0 41 Animals|*Type I Interferon|Dengue Virus|Dengue|DEAD Box Protein 58|Interferon Regulatory Factor-3|DEAD-box RNA Helicases|*Virus Infection, RNA|Interferon-Induced Helicase, IFIH1|Immunity, Innate|Virus Replication|Adaptor Proteins, Signal Transducing|Signal Transduction|Cell Line 39 DDX60 29067635 J. Neurovirol. 2017 10.1007/s13365-017-0583-3 4 1 0 64 Humans|Animals|Mice|*Chikungunya virus|Chikungunya Fever|Virus Replication|Innate Immune Response|*Disease Models, Animal|Host-Pathogen Interactions|*Regulatory Gene|Cell Line|Interferon 35 DDX60 28676847 Front Cell Infect Microbiol 2017 PMC5476785 10.3389/fcimb.2017.00269 3 19 0 64 Humans|Chlorocebus aethiops|Animals|*Hantaan virus|*Neutralizing Antibody|Hemorrhagic Fever with Renal Syndrome|*Antiviral Agents|Hantavirus|Hantavirus Infections|Antibodies, Viral|Vero Cells|*B-Lymphocytes|Viral Vaccines|Humoral Immunity|Viral Proteins|Virus Titer|Virus Replication|DDX21 protein, human|DEAD-box RNA Helicases 35 DDX60 28202761 J. Virol. 2017 PMC5391460 10.1128/JVI.02250-16 40 35 0 64 Humans|Chlorocebus aethiops|Animals|*RNA, Long Noncoding|DDX58 protein, human|*DEAD Box Protein 58|Hantaan virus|*Signal Transduction|Immunity, Innate|DEAD-box RNA Helicases|Virus Replication|Vero Cells|HEK293 Cells|Antiviral Agents 35 DFNA5 29266521 Hum. Mutat. 2017 PMC5805621 10.1002/humu.23384 6 0 0 0 Humans|Deafness, Autosomal Dominant 5|*Hearing Loss, Sensorineural|*Exon|Hearing Loss|Mutations|Pedigree|RNA Splicing|Asian Continental Ancestry Group|Receptors, Estrogen 79 DFNA5 28819893 HNO 2017 10.1007/s00106-017-0384-2 0 0 0 0 Child|Humans|Female|*Cochlear Implantation|Hearing Loss, Sensorineural|Hearing Aids|Hearing|Hearing Tests|*Syndrome|Chromosome Deletion|Mutation 79 DGCR6 28382934 Sci Rep 2017 PMC5382542 10.1038/srep45494 1 3 0 67 Humans|*Polymorphism, Single Nucleotide|*Myelin Sheath|*Schizophrenia|*Gene Expression|Promoter Regions, Genetic|DNA Methylation|Brain 24 DHRS2 29106393 Oncogene 2017 PMC5851108 10.1038/onc.2017.383 6 20 0 173 Humans|Mice|Animals|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Matrix Metalloproteinase 2|*Cell Motility|*Cell Proliferation|Squamous Cell Carcinomas|Lymphatic Metastasis|*Cell Cycle|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Mice, Nude|Signal Transduction|Xenograft Model Antitumor Assays|Apoptosis|Cell Line, Tumor|Genes, Tumor Suppressor|RNA Interference 35 DHRS2 28263391 Int. 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Chem. 2017 PMC5808777 10.1074/jbc.M117.788430 5 0 0 151 Humans|Mice|Animals|Cell Nucleolus|Ubiquitin Thiolesterase|RNA, Ribosomal|RNA Interference|DEAD-box RNA Helicases|Endopeptidases|HeLa Cells|Cell Proliferation|USP36 protein, human|DHX33 protein, human 25 DHX33 28498893 Carcinogenesis 2017 10.1093/carcin/bgx041 0 5 0 151 Humans|Cell Proliferation|Proto-Oncogene Proteins c-myc|Apoptosis|*Carcinogenesis|Cell Cycle|Transcription, Genetic|DEAD-box RNA Helicases|Promoter Regions, Genetic|Cell Line, Tumor|Cell Migration|Transcription Factor|Protein Biosynthesis|Leukemia, Myeloid, Acute|DHX33 protein, human 25 DHX33 28417008 BMC Obes 2017 PMC5381071 10.1186/s40608-017-0145-5 0 1 0 151 Adult|Child|Humans|*Basal Metabolism|Diabetes Mellitus, Type 2|Calorimetry, Indirect|Obesity|Body Mass Index|Body Weight|*Ethnic Groups|Body Composition|European Continental Ancestry Group 25 DKKL1 29206297 J. Cell. Physiol. 2017 10.1002/jcp.26313 2 1 0 98 Humans|DKK3 protein, human|*Intercellular Signaling Peptides and Proteins|Wnt Proteins|Chemokines|Promoter Regions, Genetic|Signal Transduction|Cell Proliferation|beta Catenin|DNA Methylation|Oncogene|miRNAs|Cell Line, Tumor|DKKL1 protein, human 22 DKKL1 28953627 Medicine (Baltimore) 2017 PMC5626270 10.1097/MD.0000000000008082 1 1 0 98 Humans|*Wnt Signaling Pathway|Bone Morphogenetic Proteins|Intercellular Signaling Peptides and Proteins|Genetic Markers|Bone Density|Case-Control Studies|*Arthroplasty 22 DKKL1 28488158 Neurol. Sci. 2017 10.1007/s10072-017-2964-z 3 0 0 98 Humans|Adult|*Glucocorticoids|Absorptiometry, Dual Energy X Ray|Bone Mineral Density|Osteoporosis|Osteopenia|TNFRSF11B protein, human|Osteoprotegerin|Femoral Neck|Parathyroid Hormone|Osteocalcin|*Myasthenia Gravis|fibroblast growth factor 23|Fibroblast Growth Factor|Lumbar Vertebrae|Leptin 22 DLEC1 28674222 J. Genet. 2017 10.1007/s12041-017-0770-2 2 0 0 54 Humans|Male|Female|*Prognosis|Poland|*Lung Carcinoma, Non-Small-Cell|Lung Cancer|Tumor Suppressor Proteins|Adenocarcinoma|MutL Protein Homolog 1|Biomarkers, Tumor|DNA Methylation|Squamous Cell Carcinoma|*Markers, Differentiation|Lung|RNA, Messenger|MLH1 protein, human|DLEC1 protein, human 69 DMRTA2 29239804 Mar Genomics 2017 10.1016/j.margen.2017.11.004 2 0 0 12 Male|Animals|Mexico|*Scallops|Transcriptome Analysis|Sexual Differentiation|Testis|Gonad|Transcriptome|*Disorders of Sex Development|Sequence Analysis|*Biological Phenomena 25 DMRTA2 29025924 J. Neurosci. 2017 PMC5688529 10.1523/JNEUROSCI.1535-17.2017 3 9 0 12 Mice|Animals|*Neurogenesis|*Neurons|LIM-Homeodomain Proteins|*Glia|*Cell Differentiation|Transcription Factors|Neural Stem Cells|Homeodomain Proteins|Hippocampus|Gene Expression Regulation, Developmental|Lhx2 protein, mouse|Neurog2 protein, mouse|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 25 DMRTA2 28655839 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5514752 10.1073/pnas.1705186114 6 0 0 12 TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|Neural Stem Cells|Neurogenesis|Cell Differentiation|*Nervous System|Transcription Factors|Homeodomain Proteins|Gene Expression Regulation, Developmental|Embryonic Stem Cell|Cell Cycle|Cell Proliferation 25 DMXL2 29230811 J. Pathol. 2017 10.1002/path.5017 10 0 0 56 Humans|*Whole Exome Sequencing|*Melanoma|*Mutations|DNA Mutational Analysis|*Mouth Mucosa|Proto-Oncogene Proteins c-kit|Melanocyte|DNA Copy Number Variations|Biomarkers, Tumor|Precision Medicine|Gene Dosage|Mouth Neoplasms|Molecular Targeted Therapy|Phenotype|Genetic Predisposition to Disease|Great Britain|Ireland 27 DMXL2 29078390 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5676932 10.1073/pnas.1713625114 13 0 0 56 Animals|Mice|*Microtubule-Associated Proteins|*WD40 Repeat|Neurons|*Autophagy|Dyneins|1-Alkyl-2-acetylglycerophosphocholine Esterase|Microtubules|Neurogenesis|Cell Movement|Cells, Cultured|Brain 27 DMXL2 28209974 Sci Rep 2017 PMC5314327 10.1038/srep42463 3 6 0 56 Animals|KISS1 protein, human|*Kisspeptins|*Gonadotropin Releasing Hormone|*Neurons|Hypothalamus|Luteinizing Hormone|Oestradiol|Sexual Maturation|Reproduction|Nerve Tissue Proteins|Estrogens|Brain 27 DMXL2 28168735 Photodermatol Photoimmunol Photomed 2017 PMC5505796 10.1111/phpp.12299 0 4 0 56 Humans|*Imiquimod|*Lasers, Excimer|*Psoriasis|Ultraviolet Therapy|Skin|Aminoquinolines|Th17 Cells|TNF protein, human|Tumor Necrosis Factor-alpha 27 DNAH9 28190730 Curr. Biol. 2017 10.1016/j.cub.2016.12.049 0 1 0 77 Animals|*Twins, Conjoined|Xenopus laevis|Body Patterning|Cilia|Xenopus Proteins|DNAH9 protein, human|Axonemal Dyneins|Embryo, Nonmammalian|Mesoderm 40 DNAH9 28165652 Genes Chromosomes Cancer 2017 10.1002/gcc.22448 0 0 0 77 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Palmoplantar Keratoderma, Nonepidermolytic|Tylosis|Carcinoma, Squamous Cell|Genes, BRCA2|Germ-Line Mutation|Genetic Predisposition to Disease|Exome|Pedigree|Mutation, Missense|Allele|Base Sequence|Mutations|Mutation, Nonsense|Case-Control Studies|Finland 40 dnajc10 29088834 Oncotarget 2017 PMC5650389 10.18632/oncotarget.20459 3 2 0 331 *Genome-Wide Association Study|Bone Morphogenetic Protein Receptors, Type II|Familial Primary Pulmonary Hypertension|Genetic Predisposition to Disease|Hypertension, Pulmonary|Phenotype|Mutation 32 dnajc10 28479060 Structure 2017 10.1016/j.str.2017.04.001 7 1 0 331 *Endoplasmic Reticulum-Associated Degradation|HSP40 Heat-Shock Proteins|Molecular Chaperones|Protein Folding|Protein Disulfide-Isomerases|Endoplasmic Reticulum|Membrane Proteins|Disulfides|Cell Line 32 DNAJC14 29203718 Philos. 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Sci. 2017 PMC5717533 10.1098/rstb.2016.0534 16 6 0 65 *HSP40 Heat-Shock Proteins|*Protective Factors|Molecular Chaperones|Protein Folding|HSP70 Heat-Shock Proteins|Neurodegenerative Diseases|TYRP1 protein, human|*Membrane Glycoproteins|polyglutamine|Peptides|Protein Binding|Huntington Disease|Ubiquitin|Parkinson Disease 20 DNAJC14 28693416 BMC Genomics 2017 PMC5502484 10.1186/s12864-017-3878-0 9 1 0 65 Humans|Pregnancy|Female|*Gene Regulatory Networks|*Fetal Growth|*Transcriptome Analysis|Placenta|Birth Weight|Transcriptome 20 DNTT 28678470 ACS Appl Mater Interfaces 2017 10.1021/acsami.7b06584 1 0 0 417 *Semiconductor|Membranes, Artificial|Particle Size|Metals 56 DNTT 28590478 Phys Chem Chem Phys 2017 10.1039/c7cp01958k 0 0 0 417 *Graphite|*Molecular Dynamics Simulation|*Semiconductor|Thermal Conductivity|Nanostructures|Temperature 56 DNTT 28346544 PLoS ONE 2017 PMC5367832 10.1371/journal.pone.0174699 2 3 0 417 *Induced Pluripotent Stem Cells|*V(D)J Recombination|*Mucosal-Associated Invariant T Cells|*Epigenesis, Genetic|*Cell Differentiation|Cellular Reprogramming|DNA Methylation|Transcription Factors|T Cell Receptor 56 DNTT 28218510 ACS Appl Mater Interfaces 2017 10.1021/acsami.6b15902 1 0 0 417 *Semiconductor|pentacene|Naphthacenes|Xray Diffraction|Atomic Force Microscopy|Wettability|*Films 56 DNTT 28124701 Nanoscale 2017 10.1039/c6nr08682a 1 0 0 417 *Molecular Dynamics Simulation|*Semiconductor|Thermal Conductivity|*Thiophenes 56 DOC2A 28934389 Hum. Mol. Genet. 2017 PMC5886277 10.1093/hmg/ddx255 8 5 0 31 Animals|Humans|*Phenotypes|*Brain|Chromosome Disorders|Chromosome Deletion|Zebrafish|Intellectual Disability|DNA Copy Number Variations|Heterozygotes 42 DOC2A 28864210 Eur. J. Pharmacol. 2017 10.1016/j.ejphar.2017.08.026 1 4 0 31 Rats|Animals|*Simvastatin|*Mevalonic Acid|*Cell Degranulation|*Mast Cells|Histamine Release|dinitrophenyl-bovine serum albumin|Dinitrophenols|Statins|Ionomycin|Calcium|Antigen|Bovine Serum Albumin 42 DOC2A 28539418 J. Neurosci. 2017 PMC5490061 10.1523/JNEUROSCI.0418-17.2017 10 0 0 31 Rats|Mice|Animals|*Neurotransmission|Excitatory Postsynaptic Currents|Synapses|Potential, Action|Neurons|Inhibitory Postsynaptic Currents|Glutamic Acid|Neuronal Plasticity|Patch-Clamp Techniques|Hippocampus|EEF2K protein, human|Elongation Factor 2 Kinase 42 DOC2A 28110925 J Clin Neurosci 2017 10.1016/j.jocn.2016.12.036 3 0 0 31 Humans|*Spinal Fusion|Retrospective Studies|Prospective Studies|Occipital Bone|Cervical Vertebrae|Airway Obstruction|Dysphagia|Spinal Diseases|*Neck|Intubation, Intratracheal|Dyspnea|Postoperative Complications|Postoperative Period|*Respiratory System|Cohort Studies 42 DOC2B 29274147 Elife 2017 PMC5758110 10.7554/eLife.27000 10 25 0 90 *SNAREs|*Calcium|SYT1 protein, human|*Synaptotagmin I|UNC13B protein, human|*Nerve Tissue Proteins|Exocytosis|Chromaffin Cells|Calcium-Binding Proteins|Membrane Fusion|Secretory Vesicles|*Calcium, Dietary|Binding Sites 55 DOC2B 28941037 Traffic 2017 PMC5967617 10.1111/tra.12528 5 8 0 90 *Phosphatidylinositol|*C2 Domains|IgA receptor|*Plasma Membrane|Calcium-Binding Proteins|Calcium|Nerve Tissue Proteins|Protein Binding|Protein Transport 55 DOC2B 28602209 Trends Endocrinol. Metab. 2017 10.1016/j.tem.2017.05.002 47 1 0 90 *Glucose Transporter Type 4|RAB8A protein, human|rab GTPases|Protein Transport|GTPase-Activating Proteins|Insulin|Filaments, Actin|Plasma Membrane|Cell Nucleus|Biological Transport|Glucose 55 DOC2B 28356294 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2017 PMC5451566 10.1152/ajpregu.00002.2017 12 9 0 90 Humans|Child|Diabetes Mellitus, Type 2|*Exocytosis|Insulin Secretion|SNARE|Munc18 Proteins|Insulin-Secreting Cells|Insulin|Glucose|Islets of Langerhans|Membrane Fusion|TYRP1 protein, human|*Membrane Glycoproteins|Pancreas|Nerve Tissue Proteins 55 DPP10 29176790 PLoS ONE 2017 PMC5703492 10.1371/journal.pone.0188678 0 4 0 67 Genome-Wide Association Study|*Attention Deficit Disorder with Hyperactivity|Case-Control Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Gene-Environment Interaction 105 DPP10 29049217 Medicine (Baltimore) 2017 PMC5662383 10.1097/MD.0000000000008261 7 11 0 67 *Pancreatic Cancer|Gene Ontology|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Profiling|Computational Biology|Databases, Genetic|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|Carcinogenesis|Signal Transduction 105 DPP10 28670437 Mol Autism 2017 PMC5485587 10.1186/s13229-017-0136-x 2 1 0 67 Child|Humans|*DNA Copy Number Variations|*Autism Spectrum Disorder|Comparative Genomic Hybridization|*Chinese|Chromosome Aberrations|Phenotype|Genetic Testing|Cohort Studies 105 DPP10 28630479 Sci Rep 2017 PMC5476641 10.1038/s41598-017-03326-3 11 4 0 67 Humans|Male|*Attention Deficit Disorder with Hyperactivity|*DNA Methylation|*Motivation|*Event-Related Potentials|*Attention|*Brain|Contingent Negative Variation|Reaction Time|*Boys|Orientations|Epigenesis, Genetic|Cognition|TPH2 protein, human|Tryptophan Hydroxylase 105 DPP10 28330877 J. Neurosci. 2017 PMC6596563 10.1523/JNEUROSCI.1619-16.2017 7 1 0 67 Shal Potassium Channels|Kv Channel-Interacting Proteins|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Ion Channel Gating|Cell Membrane 105 DPP3 28842433 Sci Immunol 2017 PMC5800877 10.1126/sciimmunol.aal4656 23 2 0 97 Humans|*Influenza, Human|*Vaccination|Influenza A Virus, H1N1 Subtype|Antibodies, Viral|Response, Antibody|Seasons|Transcriptome|Systems, Immune 39 DPP3 28744580 Amino Acids 2017 10.1007/s00726-017-2471-9 2 0 0 97 Humans|angiotensin I (1-7)|*Angiotensin I|*Peptide Fragments|ACE protein, human|Angiotensin Converting Enzyme|Renin-Angiotensin-Aldosterone System|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Hydrolysis|Peptides|*Amino Acids, Cyclic|Peptidases 39 DPP3 28584159 Antimicrob. Agents Chemother. 2017 PMC5527566 10.1128/AAC.02707-16 3 0 0 97 Candida albicans|Antifungal Agents|Hyphae|Fluconazole|Biofilms|Fungal Proteins|Gene Expression Regulation, Fungal|Microbial Sensitivity Tests|Phloroglucinol 39 DPP3 28416489 Cancer Res. 2017 PMC5464605 10.1158/0008-5472.CAN-16-2204 23 26 0 97 KEAP1 protein, human|*Kelch-Like ECH-Associated Protein 1|*NF-E2-Related Factor 2|*Cell Survival|Oxidative Stress|Gene Expression Regulation, Neoplastic|*B-Lymphocytes|Protein Binding|*Genes, Regulator|Ubiquitination|*Cell Transformation, Neoplastic 39 DPPA2 28359056 Cell. Physiol. Biochem. 2017 10.1159/000471246 0 0 0 42 *Induced Pluripotent Stem Cells|Cellular Reprogramming|Cell Differentiation|Fibroblasts|Cells, Cultured|*Leukemia, Myeloid, Acute 62 DRAM2 29234488 Genes Cancer 2017 PMC5724804 10.18632/genesandcancer.153 9 30 0 31 Humans|*Histone Deacetylase|*Melanoma|*Oncogene|Sirtuins|Cellular Senescence|Autophagy|Cancer, Skin|Melanocytes|Cell Line, Tumor|GLB1 protein, human|beta-Galactosidase|Short Hairpin RNA|SIRT6 protein, human|DRAM2 protein, human|Membrane Proteins 21 DRAM2 28052027 Oncotarget 2017 PMC5352419 10.18632/oncotarget.14338 10 21 0 31 Animals|Humans|Mice|*Receptors, Estrogen|*Hodgkin Disease|*Non-Obese Diabetic Mice|*Mice, SCID|Estrogen Receptor beta|Estrogen Receptor alpha|*Autophagy|Selective Estrogen Receptor Modulators|Cell Proliferation|Oestradiol|Estrogens|propionitrile|Nitriles|Cell Line, Tumor|Signal Transduction|Apoptosis|Lymphoma|DRAM2 protein, human 21 DRP2 28841174 Molecules 2017 PMC6151742 10.3390/molecules22091409 4 0 0 48 Mice|Humans|Animals|*Taraxacum|KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|NF-E2-Related Factor 2|*Polysaccharides|Protective Agents|Antioxidants|Plant Extracts|Liver|Plant Roots|Galactose|Acetaminophen|galacturonic acid|Hexuronic Acids|Molecular Weight 49 DRP2 28763741 Aquat. Toxicol. 2017 10.1016/j.aquatox.2017.07.009 2 8 0 48 Animals|*Cadmium|*Oncorhynchus mykiss|*Copper|Gills|Zinc|Water Pollutants, Chemical|*Gene Expression|EEF1A2 protein, human|Elongation Factor 1alpha|Quantitative Real Time Polymerase Chain Reaction|EEF1A1 protein, human 49 DRP2 28364294 J. Neurol. 2017 10.1007/s00415-017-8474-3 10 1 0 48 Male|Charcot-Marie-Tooth Disease, Dominant Intermediate A|Charcot-Marie-Tooth disease, X-linked, 1|*Charcot-Marie-Tooth Disease|Phenotype|Mutation|Neural Conduction|Median Nerve 49 edil3 29182679 PLoS ONE 2017 PMC5705136 10.1371/journal.pone.0188749 6 33 0 230 Mice|Animals|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|*Extracellular Signal Regulated Kinases|*Extracellular Matrix Proteins|*Osteogenesis|*Cell Differentiation|Osteoblasts|*Integrins|Osteocalcin|Phosphorylation|Alkaline Phosphatase|Signal Transduction|Gene Expression Regulation|Transcription Factor|Cell Line|Extracellular Matrix|Runx2 protein, mouse 115 EFHD2 29288926 Int. Immunopharmacol. 2017 10.1016/j.intimp.2017.12.030 2 15 0 299 Mice|Animals|*Lipopolysaccharides|*Actins|*Polymerization|*Macrophage|*Cell Migration|WASL protein, human|Wiskott-Aldrich Syndrome Protein, Neuronal|Signal Transduction|Phosphorylation|NOS2 protein, human|Nitric Oxide Synthase Type II|Arp2-3 Complex|Calcium-Binding Proteins|Immunity, Innate|Protein-Tyrosine Kinases|EFHD2 protein, mouse 54 EGR4 29198014 Inflammation 2017 10.1007/s10753-017-0701-7 4 0 0 95 Animals|Rats|rhodioloside|*Neuroprotection|Endothelial Cells|*Brain Ischemia|*Glucosides|*Phenols|Ischemia-Reperfusion Injury|Middle Cerebral Artery Occlusion|Brain|*Inhibition, Psychological|Ischemia|Complement C3 82 EGR4 28992598 Aquat. Toxicol. 2017 10.1016/j.aquatox.2017.09.027 4 0 0 95 Animals|*Zebrafish|*Fluoxetine|*Mianserin|*Amitriptyline|*Transcriptome|*Antidepressants|Embryo, Nonmammalian|Larvae|*Transcriptome Analysis|Embryonic Development|Gene Expression Regulation, Developmental|Water Pollutants, Chemical|Signal Transduction|Water|High-Throughput RNA Sequencing 82 EGR4 28860938 Cent Eur J Immunol 2017 PMC5573894 10.5114/ceji.2017.69363 7 19 0 95 EGR2 protein, human|Early Growth Response Protein 2|Early Growth Response Protein 3|EGR1 protein, human|Early Growth Response Protein 1|Lymphocyte Activation|Zinc Fingers|Muscle Spindle|Signal Transduction|Clonal Anergy|Muscle Development|*Immune System|Autoimmunity|Immune Tolerance 82 EGR4 28733346 Reproduction 2017 10.1530/REP-17-0243 3 5 0 95 Female|Cattle|Animals|*Granulosa Cells|Early Growth Response Protein 1|mRNA|Fibroblast Growth Factors|Signal Transduction|Cell Differentiation|Cells, Cultured|Cell Proliferation 82 EGR4 28464846 BMC Med. Genet. 2017 PMC5414287 10.1186/s12881-017-0408-5 0 0 0 95 Humans|Male|Mice|Animals|Republic of Korea|*Infertility, Male|Spermatogenesis|Oligospermia|Spermatocytes|Early Growth Response Transcription Factors|Spermatozoa|Reproduction|Egr4 protein, mouse 82 EHBP1 28386563 Biomed Res Int 2017 PMC5366218 10.1155/2017/7604861 0 0 0 98 Humans|*Fibroblasts|*Skin|*Phototherapy|*Diabetes Mellitus|Wound Healing|Cell Movement|Cell Proliferation|Light|Cell Line|Neoplasms 29 EIF1AY 29230367 PeerJ 2017 PMC5724404 10.7717/peerj.4133 0 0 0 31 Humans|*Transcriptome Analysis|Sequencing, RNA|Oligonucleotide Array Sequence Analysis|Transcriptome|High-Throughput Nucleotide Sequencing|RNA|Base Sequence 26 ELK4 28716526 Cancer Lett. 2017 10.1016/j.canlet.2017.07.007 9 0 0 234 Humans|Male|*Long Non-Coding RNA|ets-Domain Protein Elk-4|Prostate Cancer|prostein|*Membrane Proteins|RNA Splicing|Gene Fusions|Cell Line, Tumor|Oncogene Proteins, Fusion|Transcription, Genetic|Gene Expression Regulation, Neoplastic|Androgens|ELK4 protein, human|SLC45a3 protein, human|Membrane Transport Proteins 110 ELK4 28655758 J. Biol. Chem. 2017 PMC5555190 10.1074/jbc.M117.780130 0 3 0 234 Humans|*Ubiquitin-Specific Peptidase 7|*Gluconeogenesis|*Histone Deacetylase|Histones|Ubiquitination|Ubiquitin Thiolesterase|Protein Binding|Promoter Regions, Genetic|HEK293 Cells|Cell Line, Tumor|USP7 protein, human|SIRT7 protein, human|Sirtuins 110 ELK4 28560409 Oncol. Rep. 2017 10.3892/or.2017.5681 0 0 0 234 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Transcriptional Network|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Transcription Factors|Carcinogenesis|Biomarkers, Tumor|Upregulation|RNA, Messenger|Cell Line, Tumor|Downregulation|Genes, Homeobox 110 ELK4 28467780 Oncotarget 2017 PMC5564755 10.18632/oncotarget.17099 0 2 0 234 Humans|Male|*Prostate Cancer|Prostate|Proto-Oncogene Proteins c-ets|Sequencing, RNA|Oncogene Proteins, Fusion|Gene Fusion|Gene Expression Regulation, Neoplastic|Transcription, Genetic|Gene Expression Profiling|Cell Line, Tumor|RNA, Long Noncoding|Base Sequence|Transcriptome|SLC45a3 protein, human|Membrane Transport Proteins 110 ELK4 28275114 Biochem. J. 2017 10.1042/BCJ20160832 1 3 0 234 *Adaptor Proteins, Signal Transducing|Protein Binding|Phosphoproteins|Signal Transduction|Phosphorylation|Cell Nucleus|Nuclear Localization Signals|Cytosol|Signal, Nuclear Export|Amino Acid Sequence|EGR1 protein, human|Early Growth Response Protein 1|Cell Line|Mutation|Ternary Complex Factors 110 ELK4 28189763 Genomics 2017 10.1016/j.ygeno.2017.01.006 1 1 0 234 *DNA Methylation|Transcription Factors|Site-Specific DNA-Methyltransferase (Adenine-Specific)|DNA-Binding Proteins|DNA|Chromatin|Binding Sites|Sequence Analysis, DNA|Protein Binding|Genomics|Mutant Proteins|Genes, Homeobox 110 ENOSF1 28347776 Pharmacol. Res. 2017 10.1016/j.phrs.2017.03.021 5 0 0 12 Humans|*Capecitabine|*Polymorphism, Single Nucleotide|Dihydrouracil Dehydrogenase (NADP)|Antimetabolites, Antineoplastic|Fluorouracil|Thymidylate Synthase|Methylenetetrahydrofolate Reductase (NADPH2)|Colorectal Cancer|Genotype|Drug-Related Side Effects and Adverse Reactions|Cohort Studies 23 EPC2 29086334 Dig. Dis. Sci. 2017 10.1007/s10620-017-4821-6 1 1 0 66 *Barrett Esophagus|Adenocarcinoma Of Esophagus|Esophageal Neoplasms|Adenocarcinoma|Gastroesophageal Reflux|Esophagus|Precancerous Conditions|Metaplasia|*Disease Progression|Signal Transduction 54 EPC2 28884217 Curr. Genet. 2017 PMC6287951 10.1007/s00294-017-0742-3 3 9 0 66 Humans|Animals|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Histone Acetyltransferases|*Polycomb-Group Proteins|Chromatin|Acetylation|Histones|*Drosophila Proteins|Protein Processing, Post-Translational|*Genomics|*Regulatory Sequences, Nucleic Acid|Drosophila|Amino Acid Sequence|Tip60 protein, Drosophila|NuA4 protein, S cerevisiae|Epl1 protein, S cerevisiae 54 EPC2 28832026 Mucosal Immunol 2017 PMC5825237 10.1038/mi.2017.72 11 21 0 66 Child|Humans|*Eosinophilic Esophagitis|*Esophagus|Tight Junction|*Transforming Growth Factor|Cells, Cultured|Epithelial Cells|Transforming Growth Factor beta1|Resistance, Electrical|fluorescein isothiocyanate dextran|Fluorescein-5-isothiocyanate|Biopsies|Dextrans|Claudins 54 EPC2 28764725 J. Exp. Clin. Cancer Res. 2017 PMC5540425 10.1186/s13046-017-0572-7 3 30 0 66 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Protein Kinase Inhibitors|EGFR protein, human|Epidermal Growth Factor Receptor|Carcinoma, Squamous Cell|Erlotinib Hydrochloride|Quinazolines|Cell Line, Tumor|Xenograft Model Antitumor Assays|Antineoplastic Agents|Drug Resistance, Neoplasm|Cell Proliferation|Signal Transduction|Gene Expression Regulation, Neoplastic|Phosphorylation 54 EPC2 28104354 J. Allergy Clin. Immunol. 2017 PMC5513800 10.1016/j.jaci.2016.11.042 19 7 0 66 Humans|*Eosinophilic Esophagitis|*Esophagus|*Cell Differentiation|Interleukin-13|Epithelial Cells 54 EPG5 29263660 Int J Chron Obstruct Pulmon Dis 2017 PMC5732547 10.2147/COPD.S151909 1 1 0 85 Humans|*Bronchodilator Agents|*Chronic Obstructive Pulmonary Disease|Muscarinic Antagonists|Glycopyrrolate|Tiotropium Bromide|Adrenergic beta-2 Receptor Agonists|Indans|Forced Expiratory Volume|Quinolones|Lung|Administration, Inhalation|Treatment Outcome 47 EPG5 29174892 Curr. Biol. 2017 PMC5723708 10.1016/j.cub.2017.10.054 0 16 0 85 Humans|Animals|Mice|*Lysosome|Myoclonic Epilepsies, Progressive|*Autophagy|Neurodegenerative Diseases|Nerve Tissue Proteins|Brain|Neurons|Phenotype|Ataxia|Atrophy|Cerebellum|Cell Nucleus|Disease Models, Animal 47 EPSTI1 29217193 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.12.014 3 0 0 50 Mice|Animals|*Macrophages|Macrophage Activation|Lipopolysaccharides|STAT1 protein, human|STAT1 Transcription Factor|*Gene Expression|Cell Polarity|EPSTI1 protein, human|*Neoplasm Proteins|Signal Transduction|Interferon-gamma|Bone Marrow Cells|Inflammation|*Genes, Neoplasm|Phenotype 37 ERI3 28585566 Neuropsychopharmacology 2017 PMC5686486 10.1038/npp.2017.115 14 0 0 23 Humans|*Long Interspersed Nucleotide Elements|*Schizophrenia|*Brain|Retrotransposons|*Autopsy|Genome, Human|Insertional Mutagenesis|Dorsolateral Prefrontal Cortex|Neurons|Genomics|Polymerase Chain Reaction|Gene Expression 25 ERMN 28815590 J. Comp. Neurol. 2017 10.1002/cne.24301 6 2 0 57 Humans|Animals|Rats|F-Actin|Microfilament Proteins|Retinal Pigment Epithelium|Oligodendroglia|Microscopy, Immunoelectron|Bruch's Membrane|Actin Cytoskeleton|Fibers, Stress|Cells, Cultured|Cell Line|Phagocytosis|*Neurons|Proliferative Vitreoretinopathy|Confocal Microscopy|Photoreceptor Cells|Epithelial Cells|Retinal Pigments|juxtanodin protein, rat 24 ERMN 28418035 Sci Rep 2017 PMC5394533 10.1038/srep46548 18 1 0 57 Mice|Animals|*Cortex, Prefrontal|Dominance-Subordination|Mice, Inbred C57BL|MBP protein, human|Myelin Basic Protein|Myelin|Resilience, Psychological|Stress, Psychological 24 ESX1 28854272 PLoS ONE 2017 PMC5576694 10.1371/journal.pone.0182885 5 6 0 100 Humans|*Carcinoma, Non-Small-Cell Lung|*Afatinib|*Lung Neoplasms|Protein Kinase Inhibitors|ErbB Receptors|Erlotinib Hydrochloride|Gefitinib|Quinazolines|Drug Resistance, Neoplasm|Antineoplastic Agents|*Disease Progression|Mutation|EGFR protein, human 73 ETV3 29070620 BMJ Case Rep 2017 PMC5665345 10.1136/bcr-2017-221538 0 0 0 1655 *Histiocytosis|Proto-Oncogene Proteins c-ets|Nuclear Receptor Coactivator 2|Ultraviolet Therapy 23 ETV3 28371821 Neuro-oncology 2017 PMC5570194 10.1093/neuonc/nox027 11 2 0 1655 Child|Humans|*Telomerase|Neoplasm Recurrence, Local|Familial ependymoma|*Ependymomas|*Prognosis|Infratentorial Neoplasms|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Chromosome Aberrations|Central Nervous System Neoplasms|Chromosomes 23 ETV7 29279524 Int Heart J 2017 10.1536/ihj.16-522 0 0 0 205 Female|Humans|NPPA protein, human|*Atrial Natriuretic Factor|*Umbilical Veins|*Atrial Fibrillation|*Human Umbilical Vein Endothelial Cells|Gene Expression Regulation|Apoptosis|Cells, Cultured|Signal Transduction|phospholemman|Membrane Proteins|Phosphoproteins 43 ETV7 28693791 Crit. Rev. Oncol. Hematol. 2017 10.1016/j.critrevonc.2017.05.011 3 0 0 205 Humans|*Siblings|Proto-Oncogene Proteins c-ets|Hematopoietic Stem Cells|Repressor Proteins|Transcription Factors|Cell Differentiation|Thrombopoiesis|Gene Expression Regulation|ETV7 protein, human 43 ETV7 28134081 Clin. Exp. Rheumatol. 2017 2 0 0 205 Humans|*RNA, Micro|*Rheumatoid Arthritis|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|*Genetic Testing|Genetic Loci|Alleles|European Continental Ancestry Group|Genotype|Case-Control Studies 43 EVX2 28188691 Dev Neurobiol 2017 PMC5513754 10.1002/dneu.22490 1 1 0 14 Animals|*Zebrafish|*Xenopus laevis|*Animals, Genetically Modified|*Spinal Cord|Zebrafish Proteins|Embryo, Nonmammalian|Homeodomain Proteins|Sensory Neurons|*Anura|Transcription Factors|Tadpoles|*Spine|Brain 33 FADS3 28838557 Prostaglandins Leukot. Essent. Fatty Acids 2017 PMC5609706 10.1016/j.plefa.2017.07.001 5 3 0 58 Animals|Mice|*Docosahexaenoic Acids|docosapentaenoic acid|Fatty Acids, Unsaturated|Fatty Acid Desaturases|*Liver|mRNA|*Brain|Alternative Splicing|11-octadecenoic acid|Oleic Acids|Mice, Knockout|Downregulation|Fads3 protein, mouse 53 FADS3 28259851 BMJ Open 2017 PMC5353254 10.1136/bmjopen-2016-012475 1 0 0 58 Infant|Child|Humans|Child, Preschool|*Dermatitis, Atopic|*Prospective Studies|Indonesia|Quality of Life|*Eczema|Cohort Studies|Risk Factors|Incidence|Asian Continental Ancestry Group|Genotype 53 FADS3 28237083 Prostaglandins Leukot. Essent. Fatty Acids 2017 10.1016/j.plefa.2017.01.014 2 0 0 58 Humans|*Coronary Artery Disease|Case-Control Studies|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Fatty Acid Desaturases|*Gene Cluster|Risk Factors|*Lipids|Allele|Triglycerides|Genotype 53 FADS3 28161285 Prostaglandins Leukot. Essent. Fatty Acids 2017 10.1016/j.plefa.2017.01.006 0 0 0 58 Humans|*Methadone|*Fatty Acids|Fatty Acid Desaturases|Genotypes|Single Nucleotide Polymorphisms|Alleles|Lipid Metabolism|Pena Shokeir syndrome, type 1|*Arthrogryposis|Lipids|Multigene Family|FADS2 protein, human 53 FAIM2 29208459 Exp. Cell Res. 2017 10.1016/j.yexcr.2017.11.038 3 4 0 110 Humans|Rats|Animals|*Smokers|*Chronic Obstructive Pulmonary Disease|Smoke|Downregulation|Cells, Epithelial|Smoking|MicroRNAs|Bronchi|Apoptosis|*Protective Agents|Tobacco|Up-Regulation|Biomarkers|FAIM2 protein, human|Membrane Proteins|Apoptosis Regulatory Proteins|MIRN3202 microRNA, human 91 FAIM2 29131440 Cell Prolif. 2017 PMC6528931 10.1111/cpr.12406 37 5 0 110 *RNA, Long Noncoding|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|A549 Cells|Carcinogenesis|Apoptosis|Up-Regulation|Cell Line, Tumor|*Neoplastic Processes 91 FAIM2 28799434 Scand. J. Gastroenterol. 2017 10.1080/00365521.2017.1365166 2 0 0 110 *Gallstones|Cross-Sectional Studies|Cholecystectomy|Risk Factors|Insulin Resistance|Metabolic Syndrome|Obesity|Body Mass Index|Multivariate Analysis|Ultrasonography|Biomarkers 91 FAIM2 28761083 Mol. Psychiatry 2017 PMC6660151 10.1038/mp.2017.154 36 0 0 110 Humans|Genome-Wide Association Study|*Obsessive Compulsive Disorder|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Multifactorial Inheritance|Haplotypes|Genotype|Case-Control Studies 91 FAIM3 28126665 Microb. Pathog. 2017 10.1016/j.micpath.2017.01.038 0 0 0 72 Mice|Animals|*Jejunum|Protein Carbonylation|*Coccidiosis|Eimeria|*Gene Expression|Gene Expression Regulation|Goblet Cells|Tumor Necrosis Factor-alpha|Up-Regulation 23 FAM167A 29207374 Aging (Albany NY) 2017 PMC5764388 10.18632/aging.101333 8 1 0 62 Humans|Aged|*Cognitive Aging|*Transcriptome|Transcriptome Analysis|Aging|*Phenotype|Cognition|Gene Ontology 25 FAM167A 29193869 2017 PMC5888199 10.1002/art.40393 8 3 0 62 Humans|*Rheumatoid Arthritis|Quantitative Trait Loci|Genome-Wide Association Study|*Phenotype|*B Cells|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Gene Expression Profiling|CD4-Positive T-Lymphocytes 25 FAM167A 29070082 Biol Sex Differ 2017 PMC5657123 10.1186/s13293-017-0153-7 6 0 0 62 Male|Female|Genome-Wide Association Study|*Quantitative Trait Loci|*Lupus Erythematosus, Systemic|SNPs|Genetic Predisposition to Disease|Sjogren's Syndrome|Gene Frequency|Genotype|Autoimmune Diseases|Case-Control Studies|B Cells 25 FAM167A 28472463 Hum. Mol. Genet. 2017 PMC5886185 10.1093/hmg/ddx174 7 0 0 62 Humans|Male|*Genome-Wide Association Study|Absorptiometry, Dual Energy X Ray|Osteoporosis|Calcaneus|Bone Density|Low Bone Mineral Density|*Ultrasonography|Hip Fractures|Genotype 25 FAM167A 28289186 J. Med. Genet. 2017 PMC5610905 10.1136/jmedgenet-2016-104247 3 2 0 62 Humans|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Asian Continental Ancestry Group|European Continental Ancestry Group|Genotype|Case-Control Studies|src-Family Kinases 25 farp1 29231991 J. Cell. Biochem. 2017 10.1002/jcb.26563 3 0 0 105 Humans|*Stomach Neoplasms|*Neoplasm Staging|Neoplasm Recurrence, Local|Prognosis|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate|Disease-Free Survival|Gene Expression Regulation, Neoplastic|Transcriptome|Disease Progression|Bioinformatics 26 farp1 28860633 Sci Rep 2017 PMC5579287 10.1038/s41598-017-10392-0 3 13 0 105 cdc42 GTP-Binding Protein|rac1 GTP-Binding Protein|GTPase Activating Protein|rac GTP-Binding Proteins|Rho Guanine Nucleotide Exchange Factors|Signal Transduction|p21-Activated Kinases|Cell Movement|Protein Binding|Downregulation|RNAi|siRNA 26 FASTK 29036396 Nucleic Acids Res. 2017 PMC5737537 10.1093/nar/gkx772 8 13 0 83 *RNA, Mitochondrial|*RNA|Mitochondrial Proteins|RNA-Binding Proteins|RNA, Messenger|Gene Expression Regulation|Mitochondria|Protein-Serine-Threonine Kinases|Gene Expression 24 FASTK 28335001 Nucleic Acids Res. 2017 PMC5449608 10.1093/nar/gkx164 9 31 0 83 *Mitochondrial RNA|RNA|mRNA|Mitochondrial Proteins|Electron Transport Complex I|RNA-Binding Proteins|Mitochondria|*Endonucleases|Protein-Serine-Threonine Kinases 24 FASTKD2 29036396 Nucleic Acids Res. 2017 PMC5737537 10.1093/nar/gkx772 8 13 0 49 *RNA, Mitochondrial|*RNA|Mitochondrial Proteins|RNA-Binding Proteins|RNA, Messenger|Gene Expression Regulation|Mitochondria|Protein-Serine-Threonine Kinases|Gene Expression 22 FASTKD2 28499982 Mitochondrion 2017 10.1016/j.mito.2017.05.005 3 0 0 49 Humans|*MELAS Syndrome|*Mutations|mtDNA|Electron Transport Complex I|Acidosis, Lactic|Brain|Muscle, Skeletal|Stroke|Onset Age|FASTKD2 protein, human|Protein-Serine-Threonine Kinases 22 FBXO45 28625975 Cancer Res. 2017 PMC5540761 10.1158/0008-5472.CAN-16-1970 5 41 0 190 Male|prostate apoptosis response-4 protein|*Apoptosis Regulatory Proteins|Apoptosis|Cell Line, Tumor|Signal Transduction 33 FCGBP 29191809 J Am Heart Assoc 2017 PMC5779007 10.1161/JAHA.117.006798 8 6 0 24 *Aortic Aneurysm, Abdominal|Aortic Rupture|Elective Surgical Procedures|Time Factors 63 FCGBP 29156811 Oncotarget 2017 PMC5689701 10.18632/oncotarget.21220 2 8 0 24 Humans|Female|*Papillomavirus Infections|*Upregulation|*Squamous Cell Carcinoma of Head and Neck|Oncogene Proteins, Viral|Papillomaviridae|Human papillomavirus 16|Head and Neck Neoplasms|Carcinoma, Squamous Cell|*Transcriptional Activation|Cell Line, Tumor|Downregulation|Prognosis|Gene Expression Profiling|FCGBP protein, human|Cell Adhesion Molecules 63 FCGBP 28604600 Int J Mol Sci 2017 PMC5486068 10.3390/ijms18061245 5 5 0 24 Mice|Animals|*Toxoplasma|*Inflammasomes|*Spleen|Trefoil Factor-2|Trefoil Factor-1|Trefoil Factor-3|Mucins|Peptides|Innate Immune Responses|Mucus 63 FCGRT 29270774 Immunogenetics 2017 10.1007/s00251-017-1050-2 0 0 0 1208 Humans|Animals|Phylogeny|*Endothelial Protein C Receptor|*Class I Major Histocompatibility Molecules|Genes, MHC Class I|Evolution, Molecular|Amino Acid Sequence|Mammals|Conserved Sequence|Reptiles|Antigens, CD1|Fishes|PROCR protein, human 45 FCGRT 28786974 Transl Psychiatry 2017 PMC5611715 10.1038/tp.2017.134 4 6 0 1208 Animals|Humans|Macaca mulatta|*Schizophrenia|*Cerebral Cortex|*Brain|Immunoglobulin G|Cytokines 45 FCGRT 28785825 Immunogenetics 2017 PMC5823023 10.1007/s00251-017-1022-6 1 0 0 1208 Animals|Humans|*Macaca mulatta|Minisatellite Repeats|Fc receptor, neonatal|Fc Receptor|Histocompatibility Antigens Class I|Immunoglobulin G|Allele|Single Nucleotide Polymorphism|Promoter Regions, Genetic 45 FCGRT 28450240 Genomics 2017 10.1016/j.ygeno.2017.04.006 2 1 0 1208 Humans|Female|farletuzumab|*Carcinoma, Ovarian Epithelial|Fc receptor, neonatal|Fc Receptor|*Antibodies, Monoclonal, Humanized|Histocompatibility Antigens Class I|*Ovarian Cancer|IgG1|FOLR1 protein, human|Receptor alpha, Folate|Variable Number Tandem Repeats|Promoter Regions, Genetic|Polymorphism, Genetic|*Albumins|Genomics 45 Fcrla 29236355 Cytometry B Clin Cytom 2017 10.1002/cyto.b.21611 0 0 0 38 Humans|Mice|Animals|*Plasmacytoid Dendritic Cells|*B-Lymphocytes|Receptors, Immunologic|Flow Cytometry|FCRLA protein, human 27 Fcrla 28882568 Gene 2017 10.1016/j.gene.2017.08.032 1 0 0 38 Mice|Animals|*DNA Methylation|*Gene Expression Profiling|*Rheumatoid Arthritis|Gene Ontology|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Computational Biology|Transcription Factors|Signal Transduction|Genetic Predisposition to Disease|Bcl11b protein, mouse|Repressor Proteins|Tumor Suppressor Proteins 27 Fcrla 28879521 Curr. Top. Microbiol. Immunol. 2017 10.1007/82_2017_40 2 1 0 38 Humans|*B Cells|secretory IgM|Immunoglobulin M|Receptors, Antigen, B-Cell|Plasma Cells|T-Lymphocytes, Helper-Inducer|*Endoplasmic Reticulum|Immunoglobulin G|Receptors, Fc|immunoglobulin-binding factors|Lymphokines|FCRLA protein, human|Receptors, Immunologic 27 Fcrla 28302172 Hum. Genomics 2017 PMC5356355 10.1186/s40246-017-0101-y 7 5 0 38 Child|Humans|*Mycoplasma pneumoniae|*Bronchoalveolar Lavage Fluid|*Pneumonia, Mycoplasma|*Immunologic Deficiency Syndromes|*Transcriptome Analysis|*Gene Expression 27 FERD3L 28373146 Bone 2017 PMC5488332 10.1016/j.bone.2017.03.052 13 2 0 19 *Osteoporotic Fractures|*Genetic Loci|Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genetic Predisposition to Disease|Osteoporosis|Genetic Pleiotropy|Femoral Neck|Bone Density|Phenotypes|Diabetes Mellitus, Type 2 21 FERD3L 28220539 Congenit Anom (Kyoto) 2017 10.1111/cga.12216 1 0 0 19 Male|Humans|Infant|*Acrocephalosyndactylia|*Gene Deletion|TWIST1 protein, human|*Twist-Related Protein 1|*Nuclear Proteins|HDAC9 protein, human|*Repressor Proteins|*Histone Deacetylases|Chromosome Deletion|Craniosynostoses|Phenotype|*Nervous System Malformations 21 FERMT1 29168364 Turk. J. Pediatr. 2017 10.24953/turkjped.2017.01.009 1 0 0 210 Humans|Poikiloderma of Kindler|*Aggressive Periodontitis|*Pedigree|*Epidermolysis Bullosa|*Photosensitivity Disorders|*Blister|Neoplasm Proteins|Membrane Proteins|Mutations|FERMT1 protein, human 123 FERMT1 29130490 Int. J. Dermatol. 2017 PMC6094939 10.1111/ijd.13778 1 0 0 210 Ichthyosiform Erythroderma, Congenital|*Skin|Homozygote|1-Acylglycerol-3-Phosphate O-Acyltransferase|Lipid Metabolism, Inborn Errors|Pedigree|Mutation|Phenotypes|*Skin Diseases 123 FERMT1 28954813 J. Cell. Sci. 2017 PMC6040092 10.1242/jcs.205641 11 7 0 210 Cricetinae|Animals|PXN protein, human|*Paxillin|Talin|*Platelet|Platelet Glycoprotein GPIIb-IIIa Complex|*Platelet Activation|Cytoskeletal Proteins|Membrane Proteins|Neoplasm Proteins|Cricetulus|CHO Cells 123 FERMT1 28845732 Mol Pain 2017 PMC5593206 10.1177/1744806917730254 1 7 0 210 Rats|Animals|*Hyperbaric Oxygenation|*Pain, Neuropathic|Hyperalgesia|Rats, Sprague-Dawley|Chronic Pain|Sciatic Nerve|Spinal Cord|Signal Transduction|Disease Models, Animal|kindlin-1 protein, rat|Nerve Tissue Proteins 123 FERMT1 28667517 Sci China Life Sci 2017 10.1007/s11427-016-9044-5 2 1 0 210 Humans|*Esophageal Cancer|Neoplasm Proteins|Cell Proliferation|*Disease Progression|Membrane Proteins|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Adhesion|Focal Adhesion|*Neoplastic Processes|Cell Line, Tumor|Immunohistochemistry|Upregulation|Cell Cycle|China 123 FERMT1 28595995 J. Invest. Dermatol. 2017 PMC5977389 10.1016/j.jid.2017.05.012 12 4 0 210 Humans|Mice|Animals|*Keratinocytes|*Psoriasis|*Cell Proliferation|Skin|MicroRNAs|Cytokines|Cells, Cultured|FERMT1 protein, human|Membrane Proteins|Neoplasm Proteins 123 fes1 29176680 Sci Rep 2017 PMC5701153 10.1038/s41598-017-16577-x 8 19 0 198 *Transcriptome|*Recombinant Proteins|Pichia|Fungal Proteins|*Transcriptome Analysis|Gene Expression Regulation, Fungal|*Saccharomycetales|Proteomics 35 fes1 28714208 Adv. Mater. Weinheim 2017 10.1002/adma.201702327 15 0 0 198 *Temperature|*Electric Power Supplies|*Sulfur|Catalysis|Electrodes|Oxygen|Oxides|Metals|Nanostructures|Zinc 35 FGL1 29111387 Mol. Cell. Endocrinol. 2017 10.1016/j.mce.2017.10.014 1 8 0 118 Mice|Animals|*Insulin Resistance|*Hyperlipidemias|*Muscle, Skeletal|Endoplasmic Reticulum Stress|Diet, High-Fat|Tunicamycin|Signal Pathways|c-jun N-Terminal Kinase|Hepatocytes|*Liver|Inflammation|Fatty Liver|Phosphorylation|Palmitates|Obesity|MAP Kinase Signaling System|Insulin 50 FGL1 29107163 World Neurosurg 2017 10.1016/j.wneu.2017.10.094 3 0 0 118 *Intracranial Aneurysm|*Exome|*Whole Exome Sequencing|Genetic Predisposition|*Mutation|Pedigree 50 FGL1 28402540 J. Clin. Endocrinol. Metab. 2017 10.1210/jc.2016-3287 0 3 0 118 *Liver|Hepatocytes|Hyperglycemia|Hep G2 Cells|Reactive Oxygen Species|Signal Transduction|Neoplasm Proteins 50 FILIP1L 28683324 Cell Rep 2017 10.1016/j.celrep.2017.06.020 14 1 0 87 Humans|*Nucleosome|*Epithelial-Mesenchymal Transition|Nucleosome Remodeling and Deacetylase Complex|Chromatin|Chromatin Assembly and Disassembly|Transcription Factors|Histones|Chromosomal Proteins, Non-Histone|Gene Expression Regulation|Epigenesis, Genetic|DNA Methylation|Promoter Regions, Genetic|Protein Processing, Post-Translational|Cell Differentiation|*Oral Cancer|KDM1A protein, human|Histone Demethylases 44 FJX1 28673206 Reprod Sci 2017 PMC5933103 10.1177/1933719117716780 1 1 0 72 Humans|Animals|Female|*Endometriosis|*Endometrium|Baboon|Menstrual Cycle|Neovascularization, Pathologic|Blotting, Western|FJX1 protein, human|Membrane Proteins 26 FKBP10 29177700 Calcif. Tissue Int. 2017 10.1007/s00223-017-0360-6 4 0 0 126 Humans|*Osteogenesis Imperfecta|Heterozygote|Arthrogryposis|Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase|Phenotypes|Mutations|Bone Fracture|Bone Mineral Density|Sequencing, Next-Generation|Genotype-Phenotype Correlations|Contracture|Mutations, Missense|PLOD2 protein, human|FKBP10 protein, human|Tacrolimus Binding Proteins 100 FKBP11 29255427 Front Physiol 2017 PMC5723018 10.3389/fphys.2017.01010 4 19 0 61 *NF kB|*Aneurysm, Dissecting|Macrophages|Angiotensin II|Biomarkers 21 FKBP11 28385890 J. Biol. Chem. 2017 PMC5454108 10.1074/jbc.M116.772657 4 0 0 61 Humans|*Hydroxyproline|*Endoplasmic Reticulum|Rough Endoplasmic Reticulum|Protein Folding|Protein Structure, Secondary|Collagen|Cyclophilins|Molecular Chaperones|Collagen Type I|Extracellular Matrix Proteins|Tacrolimus Binding Proteins|Extracellular Matrix|Proline 21 FMN1 29278698 Exp. Eye Res. 2017 10.1016/j.exer.2017.12.006 3 0 0 3571 Humans|*Exfoliation Syndrome|*Genome-Wide Association Study|*Actins|Single Nucleotide Polymorphism|*Glaucoma|Genetic Predisposition to Disease|Allele|Amino Acid Oxidoreductases|Gene Frequency|Haplotypes|Genotype|Case-Control Studies|*Tetrahymenina|European Continental Ancestry Group|RNF180 protein, human|Ubiquitin-Protein Ligases 42 FMN1 28787007 PLoS ONE 2017 PMC5546675 10.1371/journal.pone.0182778 3 1 0 3571 Humans|*Whole Exome Sequencing|*Exome|*Homozygote|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Genes, Recessive|Inbreeding|Schizophrenia|*Mutations|Case-Control Studies|gamma-Aminobutyric Acid 42 FMN1 28089989 J. Cell. Sci. 2017 PMC5278671 10.1242/jcs.194704 11 0 0 3571 *Actins|RHOA protein, human|*rhoA GTP-Binding Protein|*Cells, Epithelial|Cilia 42 FMN2 29240780 PLoS ONE 2017 PMC5730144 10.1371/journal.pone.0189285 2 15 0 123 Mice|Animals|FLNA protein, human|Filamin A|Cell Movement|Cell Proliferation|Actin|Cell Differentiation|*Muscle, Skeletal|Mice, Knockout|Microcephaly|Phenotype 63 FMN2 28768717 EMBO J. 2017 PMC5623844 10.15252/embj.201796821 3 12 0 123 *Formins|Posttraumatic Stress Disorder|*Phenotypes|Microfilament Proteins|Memory|Nuclear Proteins|Risk Factors|Dementia 63 FMN2 28263325 Nat. Struct. Mol. Biol. 2017 PMC5385132 10.1038/nsmb.3387 57 7 0 123 Humans|Animals|*DNA Breaks, Double-Stranded|DNA Repair|Homologous Recombination|*Genome Mapping|Cell Cycle|Genome, Human|Cell Nucleus|*Clustering|DNA 63 FNDC1 28883884 Evid Based Complement Alternat Med 2017 PMC5573101 10.1155/2017/3275096 2 5 0 16 Rats|Animals|yinchenwuling|*Proteomics|*Drugs, Chinese Herbal|Hyperlipidemias|Traditional Chinese Medicine|Lipids|Triglycerides|Malondialdehyde|*Powders|Antioxidants|Western Blot|Lipid Metabolism 29 FNDC1 28251177 RNA Dis 2017 PMC5328418 5 4 0 16 Humans|Male|*Prostate Cancer|MicroRNAs|Receptors, Androgen|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Apoptosis|Disease Progression|FNDC1 protein, human|Neoplasm Proteins 29 FNDC1 28210664 Data Brief 2017 PMC5299139 10.1016/j.dib.2017.01.016 3 0 0 16 Humans|Male|AR protein, human|*Receptors, Androgen|FN1 protein, human|*Fibronectins|*Computational Biology|*Prostate Cancer|*Androgens|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Proliferation|Cell Movement|*Gene Expression|Signal Transduction|FNDC1 protein, human|Neoplasm Proteins 29 FNIP1 29029362 Eur. 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Neurol. 2017 10.1111/ene.13478 5 0 0 189 Myofibrillar Myopathy|*Myopathies, Structural, Congenital|Charcot Marie Tooth Disease|Hereditary Sensory and Motor Neuropathy|Distal Myopathy|*DNA-Binding Proteins|*RNA Splicing|Heat-Shock Proteins|Mutations|Protein-Serine-Threonine Kinases|HSP27 Heat-Shock Proteins|Heat-Shock Proteins, Small|Muscle, Skeletal 44 FNIP1 28970150 Gene 2017 PMC5682220 10.1016/j.gene.2017.09.044 12 35 0 189 Humans|*Folliculin|FLCN protein, human|*Tumor Suppressor Proteins|Birt-Hogg-Dube Syndrome|*Proto-Oncogene Proteins|*Genes, Tumor Suppressor|MTOR protein, human|TOR Serine-Threonine Kinases|Kidney Neoplasms|Mutation|mTORC1|Mutations, Germline|Carrier Proteins|Signal Transduction|Spontaneous Pneumothorax|AMP-Activated Protein Kinases|Lung Diseases 44 FNIP1 28583723 Cytokine Growth Factor Rev. 2017 PMC5559228 10.1016/j.cytogfr.2017.04.005 9 103 0 189 MTOR protein, human|TOR Serine-Threonine Kinases|mTORC2|mTORC1|*Signal Transduction|Rapamycin|Cell Proliferation|B Cells|Cell Differentiation|Intercellular Signaling Peptides and Proteins 44 FNIP1 28363698 Biochim Biophys Acta Mol Basis Dis 2017 10.1016/j.bbadis.2017.03.019 3 1 0 189 Mice|Animals|*AMP-Activated Protein Kinases|dihydromyricetin|*Folliculin|Muscle Fibers, Slow-Twitch|*Flavonols|FLCN protein, human|*Tumor Suppressor Proteins|*Proto-Oncogene Proteins|Muscle Fibers, Fast-Twitch|*Obesity|Insulin Resistance|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Myotubes|Signal Transduction|Muscle, Skeletal|Transcription Factors|*Dietary Fiber|Carrier Proteins 44 FNIP1 28039480 Oncotarget 2017 PMC5354783 10.18632/oncotarget.14221 6 62 0 189 Mice|Animals|*Renal Cancer|Carcinoma, Renal Cell|Birt-Hogg-Dube Syndrome|*Kidney|MTOR protein, human|TOR Serine-Threonine Kinases|Tumor Suppressor Proteins|Polycystic Kidney Diseases|*Neoplastic Processes|Proto-Oncogene Proteins|Genes, Tumor Suppressor|Mice, Knockout|Carrier Proteins|*Disease Progression|Mutations|*Nutrient|FNIP1 protein, mouse 44 foxd4 28578331 Cardiology 2017 10.1159/000462962 3 0 0 58 Humans|Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia|*Homozygote|Desmoglein 2|*Mutation|Plakophilins|*Cardiomyopathies|*Heart Ventricles|Heterozygote|*Sequencing, Whole Genome|*Arrythmia|Chinese 27 foxd4 28316121 Genesis 2017 PMC5468497 10.1002/dvg.23031 4 9 0 58 Mice|Animals|*Cell Differentiation|Neural Plate|Embryonic Stem Cell|Neurogenesis|*Neurons|Neural Stem Cells|Ectoderm|Pluripotent Stem Cell|Xenopus laevis|Transcription Factor|Gene Expression Regulation, Developmental|Cells, Cultured 27 FOXI3 28815726 J. Cell. Biochem. 2017 10.1002/jcb.26345 1 0 0 37 *Urinary Bladder Neoplasms|*RNA, Long Noncoding|*mRNA|*Carcinoma, Transitional Cell|*Urologic Neoplasms|Gene Ontology|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Downregulation|Up-Regulation|Cell Line, Tumor|Bioinformatics|Clustering|Transcriptional Activation 30 FOXI3 28728371 Asian-australas. J. Anim. Sci. 2017 PMC5838336 10.5713/ajas.17.0115 2 2 0 37 Animals|*Goat|*Foxes|*Hair Follicle|*Skin|Transcriptome|Gene Expression Profiling|Gene Expression Regulation, Developmental|Inner Mongolia 30 FOXI3 28710361 Sci Rep 2017 PMC5511229 10.1038/s41598-017-05764-5 3 2 0 37 Dogs|Animals|*Haploinsufficiency|Molar|Premolars|Incisors|Cuspid|Mandible|Tooth, Deciduous|Odontometry|Maxilla|Cephalometry|Hominids|*Phenotype 30 FOXJ3 28947819 Sci Rep 2017 PMC5613009 10.1038/s41598-017-12498-x 6 3 0 127 Cattle|Animals|Male|Mice|*Whole Exome Sequencing|*Exome|*Fertility|Artificial Insemination|Sperm|Breeding|Phenotypes|SNPs|Defensins 21 FOXJ3 28749472 Cell Death Dis 2017 PMC5550877 10.1038/cddis.2017.336 0 23 0 127 Mice|Animals|*Retinoic Acid|*Up-Regulation|*Embryonic Stem Cells|*Cell Differentiation|*Nerve Cells|mESCs|MicroRNAs|Cell Line|Basic Helix-Loop-Helix Transcription Factors|*Transcriptional Activation|herstatin|Intercellular Signaling Peptides and Proteins|Networks, Gene|MIRN219 microRNA, mouse 21 FOXL1 28867346 Stem Cell Reports 2017 PMC5599261 10.1016/j.stemcr.2017.08.001 8 31 0 224 Male|Spermatogonia|Transcription Factor|Spermatogenesis|Stem Cell|Cell Differentiation|Testis|Promyelocytic Leukemia Zinc Finger Protein|Kruppel-Like Transcription Factors|Gene Expression Regulation|Cell Cycle|Cell Proliferation|Tumor Suppressor Genes 103 FOXL1 28793269 Cell Rep 2017 10.1016/j.celrep.2017.07.043 13 0 0 224 Humans|*Cancer, Kidney|Renal Cell Carcinoma|*Nephron|Kidney|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|*B-Lymphocytes|Genomics|FOXI1 protein, human|Forkhead Transcription Factors 103 FOXN2 29090282 Biochem Biophys Rep 2017 PMC5655384 10.1016/j.bbrep.2017.10.003 9 28 0 138 Lithostathine|Pancreatitis-Associated Proteins|Inflammatory Bowel Disease|Intestinal Mucosa|Cell Line, Tumor|RNA, Messenger 28 FOXN2 28666590 Mutat. Res. 2017 10.1016/j.mrfmmm.2017.06.004 17 25 0 138 Animals|*Proliferating Cell Nuclear Antigen|*DNA Damage|DNA Repair|DNA Replication|UBE2N protein, human|Ubiquitin-Conjugating Enzymes|RAD18 protein, human|DNA-Binding Proteins|Ubiquitination|*Post-Translational Modifications|Ubiquitin-Protein Ligases|DNA Polymerases|Genomic Stability|Sumoylation|Mutagenesis|DNA|Ubiquitin|Lysine 28 FOXN2 28142295 Leuk. Lymphoma 2017 10.1080/10428194.2017.1283029 7 4 0 138 Humans|*Leukemia, T-Cell|Transcription Factors|Gene Expression Regulation, Leukemic|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Homeodomain Proteins|Homeobox Gene|Gene Expression Profiling|Cell Line, Tumor|Genes, Regulator|Activation, Transcription 28 FOXN4 28527573 Curr. Top. Dev. Biol. 2017 10.1016/bs.ctdb.2016.11.009 3 0 0 65 Humans|Animals|Mice|*Orphan Nuclear Receptors|Nuclear Receptor Subfamily 1, Group F, Member 2|*Gene Expression Regulation|Retina|Cell Differentiation|Circadian Rhythm|Retinoids 54 FOXN4 28340271 Genet. Mol. Res. 2017 10.4238/gmr16019522 5 0 0 65 Pregnancy|Cattle|Animals|Female|*Polymorphism, Single Nucleotide|Sexual Maturation|*RNA Sequence|Breeding|Fertility|Quantitative Trait Loci|Genotype|Sequencing, RNA|Transcriptome|Genetic Selection|RNA 54 FOXN4 28082864 Front Mol Neurosci 2017 PMC5183629 10.3389/fnmol.2016.00145 3 11 0 65 Mice|Animals|*Interneuron|*Spinal Cord|Motor Neurons|Transcription Factors|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Eye Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Neural Tube 54 FRMD4A 28984604 J. Alzheimers Dis. 2017 10.3233/JAD-170583 2 0 0 33 *Alzheimer Disease|*Hydrocephalus, Normal Pressure|*Polymorphism, Genetic 26 FXYD5 28620381 Front Immunol 2017 PMC5451504 10.3389/fimmu.2017.00623 8 42 0 129 Mice|Animals|Sodium-Potassium-Exchanging ATPase|Lipopolysaccharides|Acute Lung Injury|Lung|Cytokines|Bronchoalveolar Lavage Fluid|NF-kappa B|Lung Inflammation|Alveolar Epithelial Cells|Chemokine CCL2|Monocytes|Signal Transduction|Macrophages|Epithelial Cells|FXYD5 protein, mouse|Membrane Proteins 81 FXYD5 28515087 Am. J. Physiol., Cell Physiol. 2017 10.1152/ajpcell.00206.2016 2 3 0 129 Membrane Proteins|Cell Line, Tumor|Sodium-Potassium-Exchanging ATPase|*Sodium|*Disease Progression 81 FXYD5 28160550 Oncotarget 2017 PMC5421862 10.18632/oncotarget.14904 2 4 0 129 Sodium-Potassium-Exchanging ATPase|*Thyroid Cancers|Neoplasm Proteins|Prognosis|Cadherins|Membrane Glycoproteins|*Phenotypes 81 GABRP 29135068 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2017 10.1002/ajmg.b.32601 1 0 0 19 Humans|*Bipolar Disorder|*Executive Function|*Asian Continental Ancestry Group|SNPs|Genetic Predisposition to Disease|Frequencies, Allele|Haplotypes|Genetic Association Studies|Linkage Disequilibrium|Genotype|Case-Control Studies|Cognition Disorders|GABRA2 protein, human|Receptors, GABA-A|GABRP protein, human 40 GABRP 29023772 J. Neurochem. 2017 10.1111/jnc.14237 1 0 0 19 Animals|Receptors, GABA-A|Receptors, GABA|gamma-Aminobutyric Acid|Xenopus laevis|L Cysteine|Patch-Clamp Techniques|Oocytes|Redox 40 GABRP 28524180 Exp. Mol. Med. 2017 PMC5454450 10.1038/emm.2017.62 6 14 0 19 Humans|Female|Mice|Animals|*Epigenesis, Genetic|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|DNA Methylation|Promoter Regions, Genetic|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Phenotype|RNA, Messenger|Gene Expression Profiling|GABRP protein, human|Receptors, GABA-A 40 GAGE1 28631119 Pathologe 2017 10.1007/s00292-017-0311-z 0 0 0 20 Adult|Male|Humans|Adolescent|Child|*Testis|*Melanomas|Melanoma-Specific Antigens|Antigens, Neoplasm|Neoplasm Proteins|Immunohistochemistry|Biomarkers, Tumor|Membrane Proteins 48 GCM1 29153986 Stem Cell Reports 2017 PMC5785677 10.1016/j.stemcr.2017.10.014 7 21 0 325 Female|Pregnancy|Mice|Animals|*Trophoblasts|*Wnt Signaling Pathway|*Stem Cells|Placenta|Placentation|Cell Differentiation|Lineages, Cell|Transcription Factors|Gene Expression Regulation, Developmental|Morphogenesis|Embryogenesis|MET protein, human|Proto-Oncogene Proteins c-met 162 GCNT2 28839118 G3 (Bethesda) 2017 PMC5633377 10.1534/g3.117.300109 5 0 0 20 Child|Humans|*Cataract|*Mutations|gamma-Crystallins|DNA Mutational Analysis|Connexins|Pedigree|Phenotype|Base Sequence|Eye Proteins|Amino Acid Sequence|Asian Continental Ancestry Group|Sequence Alignment|Family Members|Genetic Testing|Australia|South Australia 37 GCNT2 28768505 J Transl Med 2017 PMC5541688 10.1186/s12967-017-1273-x 4 2 0 20 Adult|Humans|Child|Fetal Hemoglobin|gamma-Globins|Erythroblasts|MicroRNAs|Gene Expression Regulation|beta-Globins|RNA Binding Protein|Erythropoiesis|Nuclear Proteins|Cultured Cells|Repressor Proteins|Carrier Proteins|Downregulation|Cell Differentiation|Hematopoietic Stem Cell Transplantation 37 GCNT2 28542779 FEBS Lett. 2017 10.1002/1873-3468.12685 8 2 0 20 37 GCNT2 28278293 PLoS ONE 2017 PMC5344493 10.1371/journal.pone.0173719 0 0 0 20 *Cataract|Genetic Linkage|Pedigree|Lod Score|Sequence Deletion|Genes, Recessive|N-Acetylglucosaminyltransferases 37 GCNT2 28224043 Hum Genome Var 2017 PMC5311056 10.1038/hgv.2017.4 0 0 0 20 37 GIGYF2 29199464 Syst Biol Reprod Med 2017 10.1080/19396368.2017.1393583 3 1 0 191 Pregnancy|Male|Humans|Female|*RNA|*Sperm|Infertility, Male|Fertility|RNA, Messenger|Oocyte|Transcriptome|*Biomarkers|Live Birth 64 GIGYF2 28873462 PLoS ONE 2017 PMC5584932 10.1371/journal.pone.0184269 1 1 0 191 Humans|*Parkinson Disease|Neurodegenerative Diseases|*INDEL Mutation|*Genetic Testing|Genetic Predisposition to Disease|Alleles|Peptidyl-Dipeptidase A|Genetic Association Studies|Gene Frequency|Chinese|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|Odds Ratio|Risk Factors|*Biomarkers|China 64 GIGYF2 28698298 Genes Dev. 2017 PMC5538437 10.1101/gad.299420.117 12 2 0 191 EIF4E2 protein, human|RNA Cap-Binding Proteins|EIF4E|mRNA|Protein Binding|Amino Acid Sequence|Carrier Proteins|GRB10 protein, human|GRB10 Adaptor Protein|*Transcription Factors|Downregulation 64 GIGYF2 28585547 Nat Commun 2017 PMC5467174 10.1038/ncomms15690 32 13 0 191 *Proteomics|Biotinylation|Protein Interaction Mapping|Proteins|Protein Binding|Biological Assay 64 GIMAP4 28630090 J. Immunol. 2017 PMC5543699 10.4049/jimmunol.1601299 1 11 0 68 Humans|*Hemoglobinuria, Paroxysmal|*Transcriptome|Phosphatidylinositol Glycan|Anemia, Aplastic|Hematopoietic Stem Cells|*Signal Transduction|Pancytopenia|Flow Cytometry|Membrane Proteins|T-Lymphocytes 29 GIMAP4 28167222 Toxicol. Appl. Pharmacol. 2017 10.1016/j.taap.2017.02.001 0 0 0 68 Male|Humans|Rats|Animals|*Testis|*mRNA|*Rats, Wistar|*Sperm|Epididymis|Seminiferous Tubule|*Testicular Diseases|*Biomarkers|Organ Size|Cisplatin|Pharmaceutical Preparations 29 GLCCI1 29251255 J. Int. Med. Res. 2017 PMC5805193 10.1177/0300060516683877 4 10 0 103 Child|Humans|*Corticosteroids|*Asthma|Anti-Asthmatic Agents|Administration, Inhalation|NR3C1 protein, human|Receptors, Glucocorticoid|Single Nucleotide Polymorphisms|Pharmacogenetics|CRF receptor type 1|Receptors, Corticotropin-Releasing Hormone 47 GLCCI1 29224020 Kidney Blood Press. Res. 2017 10.1159/000485862 1 1 0 103 Humans|*Kidney Transplantation|Receptors, Glucocorticoid|Glucocorticoid|Asthma|Administration, Inhalation|*Transplant Recipients|Genotype|Polymorphism, Single Nucleotide|*Kidney|*Hypertension 47 GLCCI1 29098032 Oncol Lett 2017 PMC5652194 10.3892/ol.2017.6845 7 9 0 103 *DNA Copy Number Variations|MIRN92 microRNA, human|*RNA, Micro|MIRN124-3 microRNA, human|*Osteosarcoma|Regulatory Network, Gene|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Downregulation|Upregulation|Gene Expression|Signal Transduction|Software 47 GLCCI1 28832686 PLoS ONE 2017 PMC5568337 10.1371/journal.pone.0183709 3 2 0 103 Humans|*Intraocular Pressure|*Tonometry, Ocular|*Glaucoma, Primary Open Angle|Normal Tension Glaucoma|Genotype|Optic Disk|Genetic Predisposition to Disease|Glaucoma|Phenotype|Polymorphism, Single Nucleotide|Alleles|Genetic Variation|Case-Control Studies|Risk Factors 47 GLCCI1 28744915 Dev. Dyn. 2017 PMC5739986 10.1002/dvdy.24556 1 1 0 103 Mice|Animals|*Telencephalon|*Ganglia|Homeodomain Proteins|Olfactory Bulb|Neural Stem Cells|Interneurons|Mice, Transgenic|Neurons|Transcription Factors|Cell Differentiation|Gene Expression Regulation, Developmental|Embryo, Mammalian|Amygdala|Corpus Striatum 47 GLCCI1 28743461 Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2017 10.1016/j.cbpc.2017.07.002 0 1 0 103 Animals|Female|*Cadmium|*Cyprinidae|Gill|Interrenal Gland|Endocrine Disruptors|Cortisol|Hypothalamo-Hypophyseal System|Fish Proteins|Cadmium Poisoning|Water Pollutants, Chemical|Hepatopancreas|tacrolimus binding protein 5|Tacrolimus Binding Proteins|Glucocorticoid Receptor|Kidney|CYP11B1 47 GLDN 29109184 J. Bacteriol. 2017 PMC5738736 10.1128/JB.00362-17 6 0 0 88 30 GLDN 28939608 Appl. Environ. Microbiol. 2017 PMC5691404 10.1128/AEM.01769-17 11 0 0 88 30 GLDN 28726266 Hum. Mutat. 2017 PMC5638693 10.1002/humu.23297 4 0 0 88 Infant|Child|Humans|Adolescent|Arthrogryposis|Pedigree|Genotype|Genetic Association Studies|Phenotype|Whole Exome Sequencing|Alleles|Mutation|Contracture|GLDN protein, human|Membrane Proteins|Nerve Tissue Proteins 30 GLDN 28601286 J. Neuroimmunol. 2017 10.1016/j.jneuroim.2017.05.002 6 0 0 88 Humans|Polyradiculoneuropathy, Chronic Inflammatory Demyelinating|Contactin 1|Ranvier's Nodes|Autoantibodies|Nerve Growth Factors|Polyneuropathies|Cell Adhesion Molecules|Immunoglobulin G|ELISA 30 GLDN 28371410 Int. J. Immunogenet. 2017 10.1111/iji.12313 3 0 0 88 Humans|Leukocytes, Mononuclear|*Rheumatoid Arthritis|*Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Osteoarthritis|Protein Interaction Maps|Transcriptome|Ankylosing Spondylitis|Bioinformatics|Up-Regulation 30 GLIPR2 28876241 Acta Crystallogr D Struct Biol 2017 PMC5586249 10.1107/S2059798317011822 4 1 0 52 Animals|*Beclin-1|Scattering, Small Angle|X-Ray Diffraction|*Autophagy|Protein Conformation|Crystallography, X-Ray|Apoptosis Regulatory Proteins|Models, Molecular|Amino Acid Sequence|Membrane Proteins|Dimerization|Protein Interaction Domains and Motifs|*Mammals|Mutation|Cell Membrane|Peptides 21 glis1 29100368 Oncotarget 2017 PMC5652762 10.18632/oncotarget.20334 9 3 0 33 Humans|*Cellular Reprogramming|POU5F1 protein, human|Octamer Transcription Factor-3|Induced Pluripotent Stem Cells|SOX2 protein, human|SOXB1 Transcription Factors|Transcription Factors|Kruppel-Like Transcription Factors|Fibroblasts|Cell Differentiation|Proto-Oncogene Proteins c-myc|*Diploidy 45 glis1 29096702 Stem Cell Res Ther 2017 PMC5667457 10.1186/s13287-017-0698-8 5 9 0 33 Humans|*Human Induced Pluripotent Stem Cells|*Risk Factors|Cellular Reprogramming|Octamer Transcription Factor-3|SOXB1 Transcription Factors|Cell Differentiation|Kruppel-Like Transcription Factors|Proto-Oncogene Proteins c-myc|Transfection|Primary Cell Culture|Fibroblasts|Genetic Vectors 45 glutaminolysis 32655978 Metabolomics (Los Angel) 2017 PMC7351252 10.4172/2153-0769.1000188 0 0 0 0 Glycolysis|Oxidative Phosphorylation|Lymphocyte Activation|T Cells|Energy Metabolism|Metabolic Pathways|Cell Differentiation|Oxidation-Reduction|Mitochondria|*Antigen Presentation|Macrophages|*Rest 734 GMFB 29206597 Radiat. Res. 2017 10.1667/RR14822.1 3 0 0 125 Rats|Animals|Humans|*Spatial Memory|*Cosmic Radiation|*Proteomics|*Memory Disorders|*Hippocampus|Rats, Wistar|Dose-Response Relationship, Radiation|*Milk|Astronauts 26 GOLGA3 28782835 J. Cell. Biochem. 2017 10.1002/jcb.26328 3 1 0 189 *RNA, Long Noncoding|*Cachexia|MIRN1224 microRNA, human|MicroRNAs|Gene Modules|MIRN600 microRNA, human|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|RNA, Messenger|Wnt Signaling Pathway|Cell Line, Tumor 46 GOLGA3 28619825 Development 2017 10.1242/dev.152108 11 4 0 189 Humans|Male|*Spermatids|Sperm Tail|Spermatogenesis|*Microtubule|Sperm|Testis|Infertility, Male|Protein Transport|*Cell Differentiation|Cell Nucleus 46 GOLGA3 28539126 BMC Med Inform Decis Mak 2017 PMC5444041 10.1186/s12911-017-0454-0 4 9 0 189 Humans|*Alzheimer Disease|*Neuroimaging|*Biomarkers|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Sequencing, Whole Genome|Computational Biology|Endophenotypes|Sequencing, Next-Generation 46 GPR158 28881629 Oncotarget 2017 PMC5584230 10.18632/oncotarget.16918 8 8 0 90 33 GPR174 29017923 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.10.028 4 4 0 18 lysophosphatidylserine|*Interleukin-2|*Lipopolysaccharides|*CD4-Positive T-Lymphocytes|*Lysophospholipids|Receptors, Lysophospholipid|G-Protein-Coupled Receptors|Lymphocyte Activation|Cell Proliferation 26 GPR174 28568286 J. Clin. Lab. Anal. 2017 PMC6817210 10.1002/jcla.22258 3 0 0 18 Humans|PTPN22 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 22|*Graves Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|*Hyperthyroidism|Alleles|Asian Continental Ancestry Group|Genotype|Case-Control Studies|Liver|RNASET2 protein, human|Ribonucleases|Tumor Suppressor Proteins|GPR174 protein, human|Receptors, G-Protein-Coupled 26 GPR174 28423340 Immunity 2017 10.1016/j.immuni.2017.03.015 27 1 0 18 *T-Lymphocytes, Regulatory|*T Helper 17 Cells|*Signal Transduction|Forkhead Transcription Factors|alpha E integrins|Integrin alpha Chains|Transforming Growth Factor beta|Receptors, Transforming Growth Factor beta|Th1 Cells|*Transforming Growth Factor|Receptor, Transforming Growth Factor-beta Type II|Antigens, CD|Lymphocyte Activation|Cell Differentiation|Protein-Serine-Threonine Kinases|Cell Proliferation 26 GPR179 29023785 J. Comp. Neurol. 2017 10.1002/cne.24338 5 1 0 5 Mice|Animals|*Laminin|*Synapses|Dystroglycan|Retina|Photoreceptor Cells|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|Dystrophin|laminine|*Amino Acids, Diamino|pikachurin protein, mouse|Carrier Proteins|Nerve Tissue Proteins 25 GPR26 29268243 Biomed. Pharmacother. 2017 10.1016/j.biopha.2017.12.056 12 0 0 71 GPR39 protein, human|*G-Protein-Coupled Receptors|GPR17 protein, human|GPRC5C protein, human|*Central Nervous System Disorders|Signal Transduction|Brain 20 GPR26 28289782 Psychopharmacology (Berl.) 2017 10.1007/s00213-017-4586-9 7 0 0 71 *Rhodopsin|GPRC5C protein, human|*G-Protein-Coupled Receptors|Ligands|Signal Transduction|*Neurology 20 GPR26 28270014 J. Recept. Signal Transduct. Res. 2017 10.1080/10799893.2017.1298133 0 0 0 71 *Metabolic Syndrome|GPR39 protein, human|*Receptors, G-Protein-Coupled|Obesity|Diet|Cardiovascular Diseases 20 gpr34 29188576 Methods Mol. Biol. 2017 10.1007/978-1-4939-7465-8_21 1 0 0 33 Ligands|Protein Binding|Binding Sites|Molecular Docking Simulation|Models, Molecular|Receptors, G-Protein-Coupled|Computational Biology|Drug Discovery|Drug Design 42 gpr34 29017923 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.10.028 4 4 0 33 lysophosphatidylserine|*Interleukin-2|*Lipopolysaccharides|*CD4-Positive T-Lymphocytes|*Lysophospholipids|Receptors, Lysophospholipid|G-Protein-Coupled Receptors|Lymphocyte Activation|Cell Proliferation 42 gpr34 28715213 J. Med. Chem. 2017 10.1021/acs.jmedchem.7b00693 1 0 0 33 Humans|lysophosphatidylserine|*Lipopolysaccharides|Receptors, Lysophospholipid|*Lysophospholipids|*G-Protein-Coupled Receptors|Structure-Activity Relationship|Fatty Acids|HEK293 Cells|*Hydrophobic and Hydrophilic Interactions 42 gpr34 28040605 Domest. Anim. Endocrinol. 2017 PMC5357439 10.1016/j.domaniend.2016.12.002 0 35 0 33 Cattle|Animals|Female|Hedgehog Proteins|*Granulosa Cells|Ovarian Follicle|Theca Cells|Ovulation|Oestradiol|Progesterone|G-protein-coupled receptor 34|*Receptors, Lysophospholipid|mRNA|IGF1 protein, human|IGF-1|Gene Expression Regulation 42 GPR64 29227830 Stem Cell Res 2017 10.1016/j.scr.2017.11.017 5 0 0 39 Humans|Mice|Animals|*Pluripotent Stem Cells|stage-specific embryonic antigen-4|Stage-Specific Embryonic Antigens|Epiblast|Embryonic Stem Cells|stage-specific embryonic antigen-3|Cell Differentiation|Cells, Cultured|Cell Surface Antigens|Antigens, Tumor-Associated, Carbohydrate|NLGN4X protein, human|Cell Adhesion Molecules, Neuronal 28 GPR64 28694502 Sci Rep 2017 PMC5503986 10.1038/s41598-017-05165-8 1 31 0 39 Pregnancy|Humans|Male|Female|Mice|Animals|*Cells, Stromal|Decidua|Embryo Implantation|Progesterone|Endometrium|Uterus|Receptors, Progesterone|*Epithelial Cells|Signal Transduction|Cell Differentiation|RNA, Small Interfering|Cells, Cultured 28 GPR64 28154189 J. Biol. Chem. 2017 PMC5377759 10.1074/jbc.M116.763656 13 4 0 39 *G-Protein-Coupled Receptors|*Amino Acid Sequence|Signal Transduction|Protein Binding|Peptides|Cell Adhesion|Models, Molecular 28 GPR85 29268243 Biomed. Pharmacother. 2017 10.1016/j.biopha.2017.12.056 12 0 0 29 GPR39 protein, human|*G-Protein-Coupled Receptors|GPR17 protein, human|GPRC5C protein, human|*Central Nervous System Disorders|Signal Transduction|Brain 25 GPR85 28993767 Front Immunol 2017 PMC5622154 10.3389/fimmu.2017.01146 2 41 0 29 Adult|Infant|Infant, Newborn|Humans|Cytomegalovirus|Cytomegalovirus Infections|*Genomics|Herpesviridae Infections|Antiviral Agents|siRNA|Dendritic Cells 25 GPR85 28314853 Mol. Pharmacol. 2017 10.1124/mol.116.107714 5 0 0 29 Humans|Animals|*Ligands|GPRC5C protein, human|*G-Protein-Coupled Receptors|beta-Arrestins|Arrestins|beta-Arrestin 2|Signal Transduction|Protein Binding|Small Molecule Libraries|G Protein|Insulin Secretion|HEK293 Cells|Biological Assay 25 GPR85 28289782 Psychopharmacology (Berl.) 2017 10.1007/s00213-017-4586-9 7 0 0 29 *Rhodopsin|GPRC5C protein, human|*G-Protein-Coupled Receptors|Ligands|Signal Transduction|*Neurology 25 GRID1 29248581 Gene 2017 PMC6040674 10.1016/j.gene.2017.12.025 2 0 0 73 *Bipolar Disorder|*Exome|*Whole Exome Sequencing|Genetic Linkage|Pedigree|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Variation|Phenotype|Family 36 GRID1 28696429 Mol. Psychiatry 2017 PMC5822454 10.1038/mp.2017.137 10 18 0 73 Humans|Mice|Animals|*Dopaminergic Neurons|Receptors, Glutamate|Receptors, Metabotropic Glutamate|Cerebellum|*Schizophrenia|Mice, Knockout|GLUD1 protein, human|Glutamate Dehydrogenase|GluD1 protein, mouse 36 GRID1 28360924 Front Genet 2017 PMC5350109 10.3389/fgene.2017.00030 11 1 0 73 36 GRID1 28115213 Appetite 2017 10.1016/j.appet.2017.01.004 4 0 0 73 Adult|Humans|Newfoundland and Labrador|SNPs|*Behavior, Addictive|Genetic Predisposition to Disease|Genotype|Gene Frequency|Allele|Obesity|Receptors, Dopamine D2|*Food|Food Addiction|Canada|ERAP1 protein, human|Aminopeptidases|Minor Histocompatibility Antigens 36 GRIN3A 29138490 Sci Rep 2017 PMC5686203 10.1038/s41598-017-15917-1 5 5 0 202 *Synaptic Plasticity|*Hippocampus|Long-Term Potentiation|Synapses|Long-Term Synaptic Depression|CA1 Region, Hippocampal|Excitatory Postsynaptic Potentials|NMDA Receptors|CaM KII|*Receptors, Dopamine|Electric Stimulation 70 GRIN3A 29098351 Pediatr Cardiol 2017 10.1007/s00246-017-1760-0 3 0 0 202 Humans|*Mucocutaneous Lymph Node Syndrome|*Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Asian Continental Ancestry Group|FCGR2A protein, human|Receptors, IgG|Genetic Markers|Genotype|Coronary Artery Disease|Artery, Coronary|Inositol 1,4,5-trisphosphate 3-kinase|Phosphotransferases (Alcohol Group Acceptor)|Case-Control Studies|SMAD3 protein, human|Smad3 Protein|BTNL2 protein, human 70 GRIN3A 28638088 Sci Rep 2017 PMC5479786 10.1038/s41598-017-04198-3 4 56 0 202 Rats|Animals|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|Hematopoietic Stem Cell Mobilization|Heterocyclic Compounds|*Cancer Pain|CXCR4 protein, human|*CXCR4 Receptor|*Pain|CXCL12 protein, human|Chemokine CXCL12|*Neurons|*Signal Transduction|*Bone Cancer|NMDA receptor A1|Receptors, N-Methyl-D-Aspartate|Cells, Glial|Hyperalgesia|Spinal Cord|Up-Regulation 70 GRIN3B 28535982 Brain Res. 2017 PMC5531263 10.1016/j.brainres.2017.05.017 1 4 0 31 Animals|Mice|*Monoamine Oxidase A|*Mice, Knockout|Serotonin|para Chlorophenylalanine|*Gene Expression Regulation|Serotonin Uptake Inhibitors|Brain|Autism|Neurotransmission 21 GRIN3B 28403887 BMC Cancer 2017 PMC5388998 10.1186/s12885-017-3256-y 14 6 0 31 Humans|Male|*Histones|*Prostate|*Prostate Cancer|Epigenesis, Genetic|DNA Methylation|*Disease Progression|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|*Epigenetic|*Neoplastic Processes|Gene Expression Profiling|Cell Line, Tumor 21 GRIN3B 28132660 Genet Res (Camb) 2017 PMC6865172 10.1017/S0016672316000148 4 0 0 31 Humans|*Whole Exome Sequencing|*Mutation, Missense|*Risk Factors|*Psychotic Disorders|*Schizophrenia|N Methyl D Aspartate Receptors|Allele Frequency|Genetic Predisposition to Disease|Exome|Pedigree|Genotype|Nerve Tissue Proteins|Mutation|Case-Control Studies|Family Members 21 GRINA 29173483 J Trace Elem Med Biol 2017 10.1016/j.jtemb.2017.09.018 0 0 0 80 74 GULP1 29245900 Oncotarget 2017 PMC5725091 10.18632/oncotarget.20062 1 14 0 148 Animals|*Alzheimer Disease|*Drosophila|Amyloid beta-Protein Precursor|Secretases|Amyloid beta-Peptides|Senile Plaques|Aspartic Acid Endopeptidases|*Amyloidogenic Proteins|*Amyloidosis 37 GULP1 28642575 Nat Commun 2017 PMC5481424 10.1038/s41467-017-00037-1 37 1 0 148 *Astrocytes|*Brain Ischemia|*Phagocytes|ABCA1 protein, human|*ATP Binding Cassette Transporter 1|Microglia|Phagocytosis|Brain|*Central Nervous System|Cells, Cultured 37 GULP1 28284325 Respir Med 2017 10.1016/j.rmed.2017.02.011 0 3 0 148 Humans|*Pulmonary Emphysema|*Chronic Obstructive Pulmonary Disease|*Respiratory Mucosa|Lung|Forced Expiratory Volume|Vital Capacity|*Emphysema|Bronchi|Smoking|*Disease Progression|Smokers 37 GZMK 29232193 Endocr Regul 2017 10.1515/enr-2017-0020 0 1 0 54 Rats|Male|Animals|*Testosterone|*Testis|*Granzymes|Leydig Cells|Seminiferous Tubules|Epididymis|Spermatozoa|Rats, Sprague-Dawley|*Testosterone Congeners|Mesylates|RNA, Messenger|Gzmb protein, rat 71 GZMK 28985805 Can. J. Ophthalmol. 2017 10.1016/j.jcjo.2017.03.010 1 0 0 54 Humans|*Uveitis|Retinol-Binding Proteins|Autoantigens|Eye Proteins|Autoimmune Diseases|Autoantibodies|Retina|Arrestin 71 GZMK 28428612 Immunol. Cell Biol. 2017 10.1038/icb.2017.35 3 1 0 54 Mice|Animals|GZMB protein, human|*Granzymes|Ectromelia, Infectious|Ectromelia virus|Cytotoxic T-Lymphocytes|Perforin|Cytotoxicity, Immunologic|Cell Death|Mice, Inbred C57BL|Apoptosis|Cell Line|*Antiviral Agents 71 H6PD 28887160 Gene 2017 10.1016/j.gene.2017.09.005 5 1 0 587 Humans|*Pentose Phosphate Pathway|*DNA Replication|Glycolysis|Tricarboxylic Acid Cycle|*Fibroblasts|siRNA|Glucosephosphate Dehydrogenase|Cell Cycle|Cell Proliferation|Glucose|PRPS1 protein, human|Ribose-Phosphate Pyrophosphokinase 65 H6PD 28499147 J. Nutr. Biochem. 2017 10.1016/j.jnutbio.2017.02.021 3 0 0 587 Male|Rats|Animals|*Corticosterone|*Fructose|*NADP|*Rats, Sprague-Dawley|*Adipose Tissue, White|11-beta-Hydroxysteroid Dehydrogenase Type 1|Glucocorticoid|Adipose Tissue|*Epididymis|Metabolic Syndrome|Intra-Abdominal Fat|Obesity|Adipocytes|Endoplasmic Reticulum|Dyslipidemia 65 HABP2 29264977 Gynecol. Endocrinol. 2017 10.1080/09513590.2017.1404236 2 0 0 315 Pregnancy|Humans|Female|*Implantation, Embryo|*Endometrium|*Fertilization in Vitro|Embryo Transfer|Infertility, Female|Gene Expression Profiling|mRNA|POSTN protein, human|Cell Adhesion Molecules|HABP2 protein, human|Serine Endopeptidases 150 HEG1 28361969 Sci Rep 2017 PMC5374711 10.1038/srep45768 9 1 0 40 Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|Pleural Neoplasms|Adenocarcinoma|MUC2 protein, human|*Mucin-2|Immunohistochemistry|Antibodies, Monoclonal|Biomarkers, Tumor|Calbindin 2|Diagnosis, Differential|Membrane Glycoproteins|Specificity 37 HELB 28594346 Int J Mol Sci 2017 PMC5486056 10.3390/ijms18061233 8 92 0 55 Humans|*Replication Protein A|*DNA Helicases|*Single-Stranded DNA-Binding Protein|DNA Repair|DNA, Single-Stranded|DNA Replication|Nucleic Acid Conformation|Protein Binding|*Chromosome Structures 80 HELB 28503139 Front Hum Neurosci 2017 PMC5408787 10.3389/fnhum.2017.00201 2 0 0 55 Humans|*Transcranial Direct Current Stimulation|*Entropy|*Pilot Projects|*Head Protective Devices|*Movement|Evoked Potentials, Motor|*Brain|Motor Cortex|Transcranial Magnetic Stimulation|Electroencephalogram|COPE regimen|*Etoposide|*Antineoplastic Combined Chemotherapy Protocols|*Vincristine|*Cyclophosphamide|*Cisplatin|Cerebellum|*Finger 80 HELB 28494715 Curr Aging Sci 2017 10.2174/1874609810666170511100318 0 0 0 55 Humans|Aged|*Thumb|Geriatric Assessment|Activities of Daily Living|Reproducibility of Results|Aging|Observer Variation 80 HELB 28142130 Epilepsy Behav 2017 10.1016/j.yebeh.2016.12.009 2 0 0 55 Adolescent|Child|Humans|*Quality of Life|*Depression|*Epilepsy|*Focal Seizure|*Anxiety|Anticonvulsants|Questionnaire|*Anxiety Disorders|Psychiatric Status Rating Scales|Epilepsy, Temporal Lobe 80 HES2 29271023 Stem Cells 2017 10.1002/stem.2764 5 7 0 67 Humans|*Myocytes, Cardiac|*Human Embryonic Stem Cells|polycystic kidney disease 2 protein|polycystic kidney disease 1 protein|*TRPP Cation Channels|*Glucose|*Autophagy|*Signal Transduction|*Starvation|Cell Differentiation|Calcium|Apoptosis|Polycystic Kidney, Autosomal Dominant|Cell Line 55 HES2 28253373 PLoS ONE 2017 PMC5333912 10.1371/journal.pone.0173178 0 2 0 67 Male|Animals|Rats|*Transcriptome|ROS1 protein, human|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|*Testis|*Reproduction|Spermatogenesis|*Fishes|Gene Expression Profiling|Sperm|Gene Expression Regulation|Amino Acid Sequence|*Freshwater|Breeding|Seasons 55 HINT2 28947137 Cancer Lett. 2017 10.1016/j.canlet.2017.09.020 9 7 0 69 Humans|Carcinoma, Hepatocellular|Liver Neoplasms|*Mitochondria|Apoptosis|Reactive Oxygen Species|Deoxycytidine|Mitochondrial Proteins|Pancreatic Cancer|Antimetabolites, Antineoplastic|Membrane Potential, Mitochondrial|Calcium Channels|Up-Regulation|Hint2 protein, human 32 HINT2 28800793 Oncol. Res. 2017 10.3727/096504017X15021536183508 0 6 0 69 *Carcinoma, Non-Small-Cell Lung|*Up-Regulation|*Cyclooxygenase 2|*Lung Neoplasms|*Signal Transduction|*Catenins|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Down-Regulation|Cell Movement|Cell Line, Tumor|*Neoplastic Processes|*Prostaglandins E 32 HINT2 28333958 PLoS ONE 2017 PMC5363871 10.1371/journal.pone.0174265 15 12 0 69 *Carcinoma, Hepatocellular|fibulin|*Vimentin|*Liver Neoplasms|Calcium-Binding Proteins|*Cell Free DNA|CpG Islands|DNA Methylation|Biomarkers, Tumor|High-Throughput Nucleotide Sequencing|Prognosis|Promoter Regions, Genetic|*Epigenetic|Liver|*Intermediate Filaments|*Plasma|Epigenesis, Genetic|Thailand 32 HINT2 28264826 BMJ Open 2017 PMC5353287 10.1136/bmjopen-2016-012982 2 3 0 69 Infant, Newborn|Infant|Humans|*Hyperglycemia|B-insulin|*Insulin|Hypoglycemia|Hypoglycemic Agents|Blood Glucose|*Infant, Newborn, Diseases|*Biotin|Insulin, Regular, Human|Infant, Premature, Diseases|Clinical Protocols|*Computer|Hint2 protein, human|Mitochondrial Proteins 32 HINT2 28088787 Oncotarget 2017 PMC5355117 10.18632/oncotarget.14587 4 43 0 69 Humans|*Down-Regulation|*Histidine|*Colorectal Carcinoma|Zinc Finger E-box-Binding Homeobox 1|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|HCT116 Cells|Cell Migration|*Neoplastic Processes|Cell Line, Tumor|endothelial PAS domain-containing protein 1|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Signal Transduction|Neoplasm Staging|Upregulation|Hint2 protein, human|Mitochondrial Proteins 32 HIVEP2 29261186 Genet. Med. 2017 10.1038/gim.2017.173 4 0 0 69 Hereditary renal agenesis|*Kidney|Renal Adysplasia|*Urogenital Abnormalities|*Kidney Diseases|Limb Deformities, Congenital|Anus, Imperforate|Trachea|Anal Canal|Esophageal Atresia|Esophagus|*Solitary Kidney|*Mutations|Spine|Abnormalities, Multiple|Heart Defects, Congenital|Phenotype|*Genomics 77 HIVEP2 29241532 Cell Rep 2017 PMC5745231 10.1016/j.celrep.2017.11.053 12 8 0 69 Humans|Mice|Animals|*Receptors, Glucocorticoid|In Situ Hybridization, Fluorescence|*Protein Binding|Chromatin|Glucocorticoids|Transcription Factors|Chromatin Assembly and Disassembly|Dexamethasone|DNA-Binding Proteins|Binding Sites|Gene Expression Regulation|Promoter Regions, Genetic|Signal Transduction 77 HIVEP2 29233179 Mol Brain 2017 PMC5727961 10.1186/s13041-017-0339-2 7 2 0 69 Animals|Mice|*Mice, Knockout|*Intellectual Disability|Dendritic Spines|*Schizophrenia|Dentate Gyrus|Neurons|Disks Large Homolog 4 Protein|Brain|Disease Models, Animal|Hivep2 protein, mouse|DNA-Binding Proteins 77 HIVEP2 28515355 Oncotarget 2017 PMC5542262 10.18632/oncotarget.17597 6 16 0 69 Humans|*5 Fluorouracil|*miRNA|*Colorectal Cancer|*Colonic Neoplasms|HCT116 Cells|Antimetabolites, Antineoplastic|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|HT29 Cells|mRNA|Apoptosis|HIVEP2 protein, human|DNA-Binding Proteins|Transcription Factors 77 HIVEP2 28063951 Fish Shellfish Immunol. 2017 10.1016/j.fsi.2017.01.005 8 0 0 69 Animals|*Isavirus|*Salmo salar|*Spleen|*Transcriptome|*Transcriptome Analysis|*Virus Replication|Fish Diseases|Fish Proteins|Orthomyxoviridae Infections|Viral Load|Interferon-gamma|*Disease Susceptibility 77 HMCN1 28040546 Cancer Lett. 2017 10.1016/j.canlet.2016.12.027 5 0 0 37 Humans|*Gallbladder Neoplasms|DNA Copy Number Variations|*Gallbladder|*Carcinoma, Small Cell|Carcinoma, Neuroendocrine|*Mutations|*Sequencing, Whole Genome|Sequence Analysis, DNA|Genome|Genomics|Lymphatic Metastasis 47 HMGN3 28539318 J. 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Biochem. Physiol. B, Biochem. Mol. Biol. 2017 10.1016/j.cbpb.2017.09.003 3 0 0 20 Animals|*Pinctada|*Insulin|Sequence Alignment|Amino Acid Sequence|*IGF-Binding Proteins|cDNA|*Insulin, Regular, Human|Cloning, Molecular|Base Sequence|*Protein Binding|Open Reading Frame|Binding Site|mRNA|Expressed Sequence Tag|Sequence Homology, Amino Acid|Gene Expression Profiling|Phylogeny|Lipopolysaccharides 40 HMX2 28652139 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 2017 10.1016/j.cbpb.2017.06.007 0 0 0 20 Animals|*Pinctada|Nacre|Sequences, Amino Acid|mRNA|Transcription Factors|cDNA|Gene Expression Regulation, Developmental|RNAi|Cloning, Molecular|Promoter Regions, Genetic|Phylogeny 40 HORMAD1 29081791 Front Genet 2017 PMC5645506 10.3389/fgene.2017.00150 8 1 0 60 *Quantitative Trait Loci|*Polymorphism, Single Nucleotide|*Diabetes Mellitus, Type 2|*Obesity|Genome-Wide Association Study|Genetic Predisposition to Disease|Gene Expression Profiling 53 HORMAD1 28844861 Mol. Cell 2017 PMC5621520 10.1016/j.molcel.2017.07.027 25 12 0 60 Male|Mice|Animals|*Synapsis, Chromosomal|*Oocytes|Meiosis|meiotic recombination protein SPO11|Endodeoxyribonucleases|DNA Breaks, Double-Stranded|Prophase I|CHEK2 protein, human|Checkpoint Kinase 2|Spermatocytes|*Cell Cycle Checkpoints|Cell Cycle Proteins|Chromosomes|DNA Repair|Adenosine Triphosphatases|ATPases Associated with Diverse Cellular Activities 53 HORMAD1 28659378 EMBO J. 2017 PMC5556265 10.15252/embj.201797291 14 2 0 60 *ATPase|Mad2 Proteins|Spindle Assembly Checkpoint|Cell Cycle Proteins|ATPases Associated with Diverse Cellular Activities|Nuclear Proteins|Adaptor Proteins, Signal Transducing|Cdc20 Proteins|Spindle Apparatus|Carrier Proteins|Mitosis|Protein Binding|Crystallography, Xray 53 HORMAD1 28506208 BMC Genet. 2017 PMC5433158 10.1186/s12863-017-0508-4 1 3 0 60 Animals|*Epistasis, Genetic|Caenorhabditis elegans Proteins|*Phenotypes|Caenorhabditis elegans|Quantitative Trait Loci|Traits, Complex 53 HORMAD1 28364521 Mol. Hum. Reprod. 2017 PMC5943682 10.1093/molehr/gax004 6 2 0 60 Male|Female|Humans|*Ovary|*RNA|*Immunoprecipitation|Meiosis|Oocytes|Cell Cycle Proteins|Nuclear Proteins|Testis|Azoospermia|RNA, Messenger|*Fetus|DAZL protein, human|RNA-Binding Proteins 53 HORMAD1 28342986 Cancer Lett. 2017 10.1016/j.canlet.2017.03.029 28 0 0 60 Humans|Male|*DNA Methylation|*Oncogenes|Epigenesis, Genetic|*Germ Line|MAGEA3 protein, human|Neoplasm Proteins|*Oncogenesis|Antigens, Neoplasm|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Genes, Tumor Suppressor|DNA-Binding Proteins|Cell Line, Tumor|Genes, Regulator|DNA|CTCFL protein, human|MAGEB2 protein, human|MageA2 protein, human 53 HORMAD1 28342926 Urology 2017 10.1016/j.urology.2017.03.026 4 0 0 60 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Oligospermia|Sperm Retrieval|Sertoli Cell-Only Syndrome|Spermatogenesis|Testis|Spermatozoa 53 HOXA6 29137433 Oncotarget 2017 PMC5663605 10.18632/oncotarget.21041 6 2 0 56 36 HOXA6 28527972 Clin Neurol Neurosurg 2017 10.1016/j.clineuro.2017.05.002 9 0 0 56 Humans|Child|*Meningioma|Meningeal Neoplasms|miRNAs|Downregulation|TIMP3 protein, human|TIMP-3|Genes, p16|Prognosis|Genes, cdc|Chromosome Aberrations|Upregulation|DNA Methylation|*Epigenetic|Disease Progression|Genes, Homeobox|Epigenesis, Genetic 36 hoxc11 29137433 Oncotarget 2017 PMC5663605 10.18632/oncotarget.21041 7 2 0 92 57 hoxc11 29101335 Sci Rep 2017 PMC5670210 10.1038/s41598-017-14967-9 7 4 0 92 Humans|Sheep|Animals|*Transcriptome|*Genes, Homeobox|*Adiposity|*Obesity|Adipose Tissue|Intra-Abdominal Fat|Lipid Metabolism|Gene Expression Profiling|Gene Expression Regulation|Breeding|Hypercholesterolemia 57 hoxc11 28846832 Mol Oncol 2017 PMC5709615 10.1002/1878-0261.12133 11 21 0 92 Humans|*RNA, Long Noncoding|Nuclear Proteins|Transcription Factors|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Promoter Regions, Genetic|Cell Line, Tumor|Histone-Lysine N-Methyltransferase|*Protein Isoforms|Signal Transduction|*Extracellular Matrix|Claudins|BRD4 protein, human 57 hoxc11 28541373 Acta Biochim. 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(Shanghai) 2017 10.1093/abbs/gmx051 1 9 0 92 Mice|Animals|*Acetylation|*Histones|Acetyltransferase, Histone|p300-CBP Transcription Factors|*Transcription Factors|*Protein Processing, Post-Translational|AKT1 protein, human|Protein Kinase B alpha|Hox Genes|Chromatin Immunoprecipitation|Transcriptional Activation|Upregulation|Lysine|*Gene Expression|Promoter Regions, Genetic|RNA, Small Interfering|Hoxc11 protein, mouse|Homeodomain Proteins 57 hoxc11 28402266 Oncotarget 2017 PMC5482679 10.18632/oncotarget.16619 6 10 0 92 Humans|Female|*Uterine Cervical Neoplasms|*Homeobox Gene|*Papillomavirus Infections|Epigenesis, Genetic|oncogene protein E7, Human papillomavirus type 16|*Papillomavirus E7 Proteins|Human papillomavirus 16|Oncogene Proteins, Viral|homeobox protein HOXA13|Homeodomain Proteins|HOXB13 protein, human|histone H3 trimethyl Lys4|Histones|Repressor Proteins|Promoter Regions, Genetic|Cell Line, Tumor|DNA Methylation|Gene Expression Regulation, Neoplastic 57 hoxd11 29159938 Am. J. Phys. Anthropol. 2017 10.1002/ajpa.23361 0 0 0 136 Humans|Sacrum|Lumbar Vertebrae|Pelvis|*Spinal Diseases|African Continental Ancestry Group|Lumbosacral Region|European Continental Ancestry Group|*Musculoskeletal Abnormalities|*Obstetrics 126 hoxd11 29159235 Data Brief 2017 PMC5684501 10.1016/j.dib.2017.10.056 0 1 0 136 Animals|*Histones|*Lysine|*Xenopus laevis|*EF 1alpha|*Transcription Factors|Chromatin|Chromatin Immunoprecipitation|Epigenesis, Genetic|DNA Methylation|Promoter Regions, Genetic|*Cell Line|Polymerase Chain Reaction 126 hoxd11 28681415 Dev. Dyn. 2017 PMC5601294 10.1002/dvdy.24543 2 14 0 136 Animals|*Retinoic Acid|Hedgehog Proteins|*Wings, Animal|Limb Buds|Body Patterning|Gene Expression Regulation, Developmental|Trans-Activators|Homeodomain Proteins|Limb|Signal Transduction|*Chickens 126 hoxd11 28442438 Gene Expr. Patterns 2017 10.1016/j.gep.2017.04.003 1 0 0 136 Animals|*Flounder|*Animal Fins|Body Patterning|Homeodomain Proteins|Gene Expression Regulation, Developmental|Extremities|Transcription Factors|*Germ Cells|Ectoderm|Biological Evolution|Fishes|Phylogeny|Larvae 126 hoxd11 28205287 Dev. Dyn. 2017 10.1002/dvdy.24493 4 0 0 136 Animals|*Limb Buds|Hedgehog Proteins|Body Patterning|Morphogenesis|Gene Expression Regulation, Developmental|Extremities|Signal Transduction 126 HSPB3 29218493 Lasers Med Sci 2017 10.1007/s10103-017-2409-1 1 0 0 1045 Humans|Skin|Wound Healing|Lasers, Gas|Keratinocytes|Models, Biological 48 HSPB3 28854361 Cell Rep 2017 PMC5583511 10.1016/j.celrep.2017.08.018 11 23 0 1045 Animals|*Lamin Type A|*Cell Nucleus|Heat-Shock Proteins|HSP27 Heat-Shock Proteins|Protein Binding|Chromatin|Cell Differentiation 48 HSPB3 28425051 Cell Stress Chaperones 2017 PMC5465040 10.1007/s12192-017-0794-9 3 0 0 1045 Rats|Animals|*Phosphorylation|*Up-Regulation|*Infarction, Middle Cerebral Artery|CRYAB protein, human|*alpha-Crystallin B Chain|HSPB1 protein, human|*HSP27 Heat-Shock Proteins|Heat-Shock Proteins, Small|Heat Shock Proteins|Neuroprotection|*Transcriptional Activation|Neurons|Hspb1 protein, rat 48 HSPB3 28202467 Biol Open 2017 PMC5374404 10.1242/bio.024661 4 14 0 1045 Animals|Humans|*Centrioles|Cell Cycle Proteins|Protein-Serine-Threonine Kinases|Drosophila Proteins|Drosophila melanogaster|Intracellular Signaling Peptides and Proteins|Cell Cycle|Microtubule-Associated Proteins|Phosphorylation|Protein Binding|Cell Line|STIL protein, human|PLK4 protein, human|Ana2 protein, Drosophila 48 HSPB3 28181153 Cell Stress Chaperones 2017 PMC5465030 10.1007/s12192-017-0769-x 6 4 0 1045 Humans|Animals|HSPB1 protein, human|HSP27 Heat-Shock Proteins|CRYAB protein, human|alpha-Crystallin B Chain|Heat-Shock Proteins|Heat-Shock Proteins, Small|Adaptor Proteins, Signal Transducing|Apoptosis Regulatory Proteins|HSP70 Heat-Shock Proteins|Protein-Serine-Threonine Kinases|Protein Binding|Cell Line|BAG3 protein, human|HSPB2 protein, human|HSPB8 protein, human 48 HSPB3 28144995 Hum. Mutat. 2017 10.1002/humu.23189 12 1 0 1045 Humans|*Heat-Shock Proteins, Small|HSPB1 protein, human|HSP27 Heat-Shock Proteins|*Mutations|Charcot-Marie-Tooth Disease|Hereditary Sensory and Motor Neuropathy|Heat-Shock Proteins|Protein-Serine-Threonine Kinases|Mutations, Missense|Muscle Weakness|BAG3 protein, human|Adaptor Proteins, Signal Transducing|Apoptosis Regulatory Proteins 48 HTATSF1 28720891 Sci Rep 2017 PMC5515956 10.1038/s41598-017-06033-1 15 0 0 139 Humans|*Whole Exome Sequencing|*Autism Spectrum Disorder|Saudi Arabia|Exome|Genetic Predisposition to Disease|Mutation|Disorder, Neurodevelopmental|Intellectual Disability|GLT8D1 protein, human|Glycosyltransferases 26 HTRA3 29266444 J. Mol. Recognit. 2017 10.1002/jmr.2698 0 0 0 62 Pregnancy|Female|Humans|*PDZ Domains|Serine Endopeptidases|peptide B|High-Temperature Requirement A Serine Peptidase 1|*Halogens|High-Temperature Requirement A Serine Peptidase 2|Amino Acid Sequence|Ligands|Peptides|Serine Proteases|acetyl-(2-naphthylalanyl)(2)-4-chlorophenylalanyl-(3-pyridyl)alanyl(3)-seryl-tyrosyl-n5-aminocarbonylornithyl-tryptophyl-tyrosyl-prolyl-alaninamine|Oligopeptides|Mitochondrial Proteins|HtrA1 protein, human|HTRA3 protein, human|HtrA4 protein, human 77 HTRA3 28860718 Drug Des Devel Ther 2017 PMC5574596 10.2147/DDDT.S134518 8 21 0 62 peoniflorin|*Monoterpenes|*Glucosides|Paeonia|*Upregulation|Bridged-Ring Compounds|Glycosides|*Transcriptional Activation|Cell Line, Tumor|Cell Proliferation|Pancreatic Neoplasms 77 HTRA3 28741928 ACS Comb Sci 2017 10.1021/acscombsci.7b00051 1 0 0 62 Peptide Library|Amino Acid Sequence|PDZ Domains|Serine Endopeptidases|Combinatorial Chemistry Techniques|Substrate Specificity|Structure-Activity Relationship 77 HTRA3 28716573 Exp. Mol. Pathol. 2017 10.1016/j.yexmp.2017.07.002 2 0 0 62 Humans|*Colorectal Carcinoma|Immunohistochemistry|Epithelial-Mesenchymal Transition|Prognosis|Biomarkers, Tumor|Neoplasm Invasiveness|Keratin|Serine Endopeptidases|Stromal Cells|HTRA3 protein, human 77 hus1b 28666868 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.06.159 0 14 0 18 Humans|Cell Cycle Proteins|DNA-Binding Proteins|DNA Damage|Exonucleases|Nuclear Proteins|Phosphorylation|Protein Binding|polyanions|*Polymers|Rad17 protein, human 32 ICA1 28877068 J. Cardiovasc. Pharmacol. 2017 10.1097/FJC.0000000000000536 0 0 0 128 Animals|Rats|Mice|*P Glycoprotein|*Blood-Brain Barrier|Tomography, X-Ray Computed|ABCB1 protein, human|*ATP Binding Cassette Transporter, Subfamily B|*Positron Emission Tomography|Radiopharmaceuticals|Carbon Radioisotopes|ATP Binding Cassette Transporter, Subfamily G, Member 2|ATP-Binding Cassette Transporters|Tissue Distribution|*Biological Transport 106 ICA1 28832686 PLoS ONE 2017 PMC5568337 10.1371/journal.pone.0183709 3 2 0 128 Humans|*Intraocular Pressure|*Tonometry, Ocular|*Glaucoma, Primary Open Angle|Normal Tension Glaucoma|Genotype|Optic Disk|Genetic Predisposition to Disease|Glaucoma|Phenotype|Polymorphism, Single Nucleotide|Alleles|Genetic Variation|Case-Control Studies|Risk Factors 106 ICA1 28746893 Toxicol In Vitro 2017 10.1016/j.tiv.2017.07.015 2 0 0 128 Animals|Rats|tariquidar|*Quinolines|Multidrug Resistance|ATP Binding Cassette Transporter, Subfamily G, Member 2|ATP Binding Cassette Transporter, Subfamily B, Member 1|Blood-Brain Barrier|ATP-Binding Cassette Transporters|Carbon Radioisotopes|Positron-Emission Tomography|Tetrahydroisoquinolines|Biological Transport|Neoplasm Proteins|Dose-Response Relationship, Drug|Cardiovascular System 106 ICA1 28583845 Biochem. Pharmacol. 2017 10.1016/j.bcp.2017.05.020 1 5 0 128 Muscle, Smooth, Vascular|Myocytes, Smooth Muscle|3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester|Calcium Channels, L-Type|cAMP Dependent Protein Kinase|Calcium Channel Agonists|Patch-Clamp Techniques 106 ICA1 28067902 Nat. Neurosci. 2017 10.1038/nn.4472 26 0 0 128 *Memory, Episodic|*Hippocampus|Memory, Spatial|Cortex, Prefrontal|Maze Learning|Neural Pathways|Neurons|Memory, Short-Term 106 IFRD1 29094309 Dig. Dis. Sci. 2017 PMC6167971 10.1007/s10620-017-4819-0 1 3 0 110 Humans|*Colon Cancers|Adenocarcinoma|Biomarkers, Tumor|Immediate-Early Proteins|Membrane Proteins|IFRD1 protein, human 74 IFRD1 29091322 J. Bone Miner. Res. 2017 10.1002/jbmr.3334 6 3 0 110 Humans|Female|Mice|Animals|*Osteogenesis|*Interferon|TNFSF11 protein, human|RANK Ligand|Osteoclasts|Bone Resorption|Cell Differentiation|NFATC Transcription Factors|Osteoblasts|NF-kappa B|ent-7beta,14-dihydroxy-11alpha-methoxy-18-aldehyde-11beta-20-epoxy-kaur-16-en-15-one|*Diterpenes|Bone Density Conservation Agents|NF-KappaB Inhibitor alpha|Bone|Osteoporosis|Signal Transduction|Ovariectomy 74 IFRD1 28181167 J. Physiol. Biochem. 2017 10.1007/s13105-017-0552-6 28 1 0 110 Humans|*Diet, Mediterranean|Nuts|Diet, Fat-Restricted|Risk Factors|Cardiovascular Diseases|Olive Oil|Body Mass Index|Obesity|*Inflammation|Blood Pressure|DNA Methylation|Processes, Epigenetic|*Blood Cells|IFRD1 protein, human|Immediate-Early Proteins 74 IFRD1 28107769 FEBS J. 2017 10.1111/febs.14019 0 5 0 110 Mice|Animals|*Adipocytes, Brown|*Interferon|Adipose Tissue, Brown|Thermogenesis|Adipose Tissue, White|Uncoupling Protein 1|Adipocytes, Beige|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Gene Expression Regulation|Gene Expression|Mitochondrial Proteins|Mice, Knockout|Adipose Tissue, Subcutaneous|Cyclic AMP Response Element-Binding Protein|*Antiviral Agents|Adrenergic Agents|Ifrd1 protein, mouse|Membrane Proteins 74 IGIP 29028177 Endocr. Res. 2017 10.1080/07435800.2017.1379023 1 0 0 16 Humans|*Glucagon-Like Peptide 1|*Diabetes Mellitus, Type 2|*Metabolic Syndrome|*Gastric Inhibitory Polypeptide|Incretin|*Postprandial Period|Blood Glucose|C-Peptide|Glucagon|Insulin|gastric inhibitory polypeptide receptor|*Receptors, Gastrointestinal Hormone|Glucose 29 IGIP 30595906 Curr Health Sci J 2017 PMC6286449 10.12865/CHSJ.43.04.15 0 0 0 16 Humans|Pregnancy|Female|Adult|Cesarean Section|Pregnancy Outcome|Pregnancy in Diabetics|Insulin Infusion Systems|Gestational Age|*Parturition|Diabetes Mellitus, Type I|Blood Glucose|Fetus 29 IGIP 28751952 Craniomaxillofac Trauma Reconstr 2017 PMC5526704 10.1055/s-0036-1584891 1 0 0 16 Humans|Maxilla|Crown|Surgery, Computer-Assisted|Tomography, X-Ray Computed|Models, Anatomic|*Prosthesis Implantation|*Artificial Limbs|Stents 29 IGLL5 28472177 PLoS ONE 2017 PMC5417601 10.1371/journal.pone.0176879 5 18 0 24 Humans|Child|UCHL1 protein, human|*Ubiquitin Thiolesterase|*Glioma|Cell Proliferation|CTNNB1 protein, human|beta Catenin|Signal Transduction|Cell Line, Tumor|*Cancer Stem Cell|Gene Expression Regulation, Neoplastic|Cell Migration|DNA Methylation|Genes, sis|Ubiquitins|POSTN protein, human|Cell Adhesion Molecules 21 IGLL5 28185911 Genomics Proteomics Bioinformatics 2017 PMC5339410 10.1016/j.gpb.2016.12.002 1 1 0 24 Adult|Male|Child|Humans|*Primary Myelofibrosis|*Siblings|*Twins, Monozygotic|JAK2 protein, human|Janus Kinase 2|Thrombocythemia, Essential|Calreticulin|Receptors, Thrombopoietin|Myeloproliferative Disorders|Mutations|Bone Marrow|*Transcriptome Analysis|Genes, Regulator 21 IGSF11 29180896 Cancer Manag Res 2017 PMC5691938 10.2147/CMAR.S147326 4 9 0 18 Humans|CTLA4 protein, human|CTLA-4 Antigen|antigens, CD200|*Antigens, CD|*Malignancies|*B-Lymphocytes|Immunotherapy|Antibodies, Monoclonal|CD28 Antigens|Immune Tolerance|Self Tolerance|Lymphocyte Activation 27 IGSF11 29123028 J. Biol. Chem. 2017 PMC5766970 10.1074/jbc.RA117.000113 5 0 0 18 Male|Mice|Animals|*Blood-Testis Barrier|Sertoli Cells|Seminiferous Epithelium|Spermatogenesis|Zonula Occludens-1 Protein|*Cell Adhesion Molecules|*Cell Adhesion|Occludin|Tight Junctions|Adherens Junctions|Phosphoproteins|Fertility 27 IGSF11 29085063 Nat Ecol Evol 2017 10.1038/s41559-017-0364-7 8 0 0 18 Animals|Phylogeny|*Genome|Genetic Speciation|Sympatric Species|Hybridization, Genetic|Gene Flow|Biological Evolution|Phenotype|Songbirds|Genomics|Australia|Papua New Guinea 27 IGSF11 28882899 Diabetes 2017 10.2337/db17-0311 10 0 0 18 Humans|*Glucose|Diabetes Mellitus, Type 2|*Pancreatic Islets|*Hyperglycemia|Insulin Secretion|Insulin|*Gene Expression|DNA Methylation|RNA, Messenger|*Biochemical Phenomena 27 IGSF11 28867483 J. Biotechnol. 2017 10.1016/j.jbiotec.2017.08.023 6 0 0 18 Animals|Humans|*Membrane Proteins|*Binding Protein|Peptide Library|Immunoglobulin Fab Fragments|Protein Binding|Cloning, Molecular|Receptors, Cell Surface|Ligands|Fluorescence Activated Cell Sorting|PROCR protein, human|Endothelial Protein C Receptor|Cell Membrane|Surface Plasmon Resonance 27 IGSF11 28097057 PeerJ 2017 PMC5228514 10.7717/peerj.2843 9 2 0 18 Animals|*Animal Fins|*Pigmentation|Zebrafish|Cichlid|Fish Proteins|Phenotype|Gene Expression Regulation, Developmental|*Gene Expression|Biological Evolution|Tanganyika 27 IGSF11 28075471 Int. J. Mol. Med. 2017 PMC5358716 10.3892/ijmm.2017.2850 1 0 0 18 Mice|Animals|*Corticosterone|Depression|Hippocampus|*Gene Expression|Behavior, Animal|Fluoxetine|Disease Models, Animal 27 IGSF3 28966687 Exp Ther Med 2017 PMC5613201 10.3892/etm.2017.4907 2 0 0 44 Humans|*Mucocutaneous Lymph Node Syndrome|Endothelial Cells|Coronary Aneurysm|*Microarray Analysis|Up-Regulation|Biomarkers|Gene Expression 20 ILDR1 29224747 Int. J. Pediatr. Otorhinolaryngol. 2017 10.1016/j.ijporl.2017.09.018 3 2 0 64 Humans|Iran|*Hearing Loss|*Deafness|*Sequencing, Next-Generation|*Mutation, Missense|Hearing Loss, Sensorineural|Pedigree|Mutations|Myosin Heavy Chains|Asian Continental Ancestry Group|ILDR1 protein, human|Receptors, Cell Surface 35 ILDR1 28945813 PLoS ONE 2017 PMC5612695 10.1371/journal.pone.0185281 3 1 0 64 Humans|*Frameshift Mutation|*Genotype-Phenotype Correlation|*Mutations|Pedigree|Genes, Recessive|Exome|Homozygote|Heterozygote|Hearing Loss, Sensorineural|Sequencing, Whole Exome|Genotype|Genetic Predisposition to Disease|Hearing Loss|Deafness|Phenotype|ILDR1 protein, human|Receptors, Cell Surface 35 ILDR1 28785060 Sci Rep 2017 PMC5547134 10.1038/s41598-017-07530-z 1 20 0 64 Animals|*Splicing Factors|*RNA Precursors|Tight Junctions|*RNA Splicing|Deafness|Membrane Proteins|Mutations|Epithelial Cells|Cell Line|Cell Nucleus|*Biophysical Phenomena|Cultured Cells 35 ILDR1 28719732 2017 PMC5874801 10.1002/art.40216 9 2 0 64 Humans|Child|*Genome-Wide Association Study|*Arthritis, Juvenile|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Rheumatoid Factor|Case-Control Studies 35 ILDR1 28713423 Front Genet 2017 PMC5491932 10.3389/fgene.2017.00095 1 2 0 64 Hearing Loss, Sensorineural|Hearing Loss|Genes, Recessive|Deafness|Pedigree|Mutation|Receptors, Cell Surface 35 ILDR1 28461473 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5441773 10.1073/pnas.1701006114 10 0 0 64 Mice|Animals|Tight Junction|*Biological Transport|Claudins|Carrier Proteins|Ildr1 protein, mouse|Receptors, Cell Surface 35 ILDR1 28322503 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38153 4 0 0 64 Child|Humans|*Hearing Loss|*Phenotype|*Mutation|Hearing Loss, Sensorineural|Pedigree|Heterozygote|Exome|Genetic Association Studies|Asian Continental Ancestry Group|Sequencing, Whole Exome|Amino Acid Sequence|RNA Splicing|Steel|Puerto Rico|COL27A1 protein, human|Fibrillar Collagens|ILDR1 protein, human|Receptors, Cell Surface 35 immp2l 29152845 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2017 10.1002/ajmg.b.32608 1 0 0 32 Humans|*Autism Spectrum Disorder|Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Exons|Cohort Studies|Case-Control Studies|Neurodevelopmental Disorders|Family|Tourettes Syndrome|IMMP2L protein, human|Endopeptidases 57 immp2l 28703400 Andrologia 2017 10.1111/and.12848 0 1 0 32 Male|Mice|Animals|*Antioxidants|*Mitochondria|Plastoquinone|Oxidative Stress|*Spermatogenesis|Reactive Oxygen Species|Apoptosis|Testis|Aging 57 immp2l 28676647 Sci Rep 2017 PMC5496893 10.1038/s41598-017-04393-2 6 2 0 32 Humans|*Keratoconus|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Cornea|Genotype|Case-Control Studies|Odds Ratio|Whites 57 immp2l 28316022 Neurochem. Res. 2017 10.1007/s11064-017-2207-y 1 3 0 32 *Mitochondrial Membranes|Membrane Potential, Mitochondrial|*Hypoxia|Mitochondria|Mitochondrial Proteins|Cell Death|Viability, Cell|Neuroprotective Agents|Neurons|Reactive Oxygen Species|Brain Ischemia|Oxidative Stress|Mutation|Brain Injuries|Endopeptidases|Oxygen|Glucose 57 immp2l 28283553 Arch. Dis. Child. Fetal Neonatal Ed. 2017 PMC5563277 10.1136/archdischild-2016-311545 5 1 0 32 Infant, Newborn|Humans|Infant|*Genome-Wide Association Study|*Infant, Extremely Premature|*Sepsis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Gestational Age|Risk Factors|Cohort Studies 57 immp2l 28207827 PLoS ONE 2017 PMC5313182 10.1371/journal.pone.0172365 3 0 0 32 *Polymorphism, Single Nucleotide|*Keratoconus|Czech Republic|Genetic Predisposition to Disease|Genetic Association Studies|*Cohort Studies|Genome-Wide Association Study|Cornea|Genotype 57 IMPG1 28644393 Genes (Basel) 2017 PMC5541303 10.3390/genes8070170 3 2 0 26 Humans|*Proteoglycans|Vitelliform Macular Dystrophy|*Mutations|*Retina|Eye Proteins|*Extracellular Matrix|Extracellular Matrix Proteins|Pedigree|*Vision Disorders|Tomography, Optical Coherence 29 INSL4 28675750 J Perinat Med 2017 PMC5630498 10.1515/jpm-2017-0064 3 7 0 17 Infant, Newborn|Humans|Pregnancy|Female|*Fetal Growth|*Placenta|Birth Weight|Gestational Age|Infant, Small for Gestational Age|Fetal Growth Retardation|*Regulatory Genes|Gene Expression Profiles|PLAC1 protein, human|Pregnancy Proteins 45 INSRR 29156593 Int J Mol Sci 2017 PMC5713427 10.3390/ijms18112461 0 11 0 284 INSR protein, human|insulin receptor-related receptor|*Receptor, Insulin|FN1 protein, human|*Fibronectins|*Mutagenesis, Site-Directed|Protein Structure, Tertiary|Antigens, CD|Phosphorylation|Glycosylation|Amino Acid Sequence 86 INSRR 28825638 Int J Mol Sci 2017 PMC5578186 10.3390/ijms18081799 4 19 0 284 Mice|Swine|Animals|*Insulin|*Cell Differentiation|*Signal Transduction|3T3-L1 Cells|Adipogenesis|Adipocytes|Lipid Metabolism|PPAR gamma|*Muscle|Cell Proliferation|Cells, Cultured|Lipids 86 INSRR 28438671 Biochimie 2017 10.1016/j.biochi.2017.04.002 3 5 0 284 INSR protein, human|insulin receptor-related receptor|*Receptor, Insulin|*Insulin-Secreting Cells|*Insulin Receptor Substrate 1|*Phosphorylation|Insulin|AKT1 protein, human|Protein Kinase B|Signal Transduction|Pancreatic Islets|Apoptosis|Cell Line|Antigens, CD|Hydrogen-Ion Concentration|Actin Cytoskeleton 86 INSRR 30695555 Zh Vyssh Nerv Deiat Im I P Pavlova 2017 1 0 0 284 Mice|Animals|insulin receptor-related receptor|*Mice, Knockout|*Gene Knockout Techniques|*Alkali|*Receptor, Insulin|Aggression|Social Behavior|Signal Transduction|Swimming|Phenotype 86 IPO7 29217617 Mol. Cell Proteomics 2017 PMC5930409 10.1074/mcp.O116.065920 1 0 0 322 Humans|*Co-Immunoprecipitation|Protein Interaction Mapping|Protein Binding|Proteins|Multiprotein Complexes|Proteomics|Mass Spectrometry|Antibodies 55 IPO7 28390868 Gastroenterology 2017 10.1053/j.gastro.2017.03.050 12 6 0 322 Humans|Mice|Animals|*Spectrin|*Small Noncoding RNA|*Heterografts|*Nuclear Envelope|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|*Up-Regulation|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|Cell Movement|Cell Line, Tumor|Biomarkers, Tumor|Signal Transduction|Apoptosis|Xenograft Model Antitumor Assays 55 IRGC 28443109 Front Plant Sci 2017 PMC5387083 10.3389/fpls.2017.00509 3 1 0 17 *Alleles|*Phosphorus|Rice|Genes, Plant|Quantitative Trait Loci|Plant Proteins|Soil|South America 32 IRX4 29131521 IUBMB Life 2017 10.1002/iub.1692 1 3 0 60 Humans|Neoplasm Recurrence, Local|*Colorectal Cancer|Prognosis|Carcinoembryonic Antigen|Kaplan-Meier Estimate|Biomarkers, Tumor|Neoplasm Staging|Disease-Free Survival|*Complement Factor B|Risk Factors|*Heat Shock|HSF4 protein, human|Heat Shock Transcription Factors|DUSP26 protein, human|Dual-Specificity Phosphatases|Mitogen-Activated Protein Kinase Phosphatases 63 IRX4 28430825 PLoS Genet. 2017 PMC5419579 10.1371/journal.pgen.1006719 16 1 0 60 Humans|Male|Female|*Genome-Wide Association Study|*Adiposity|*Obesity|Waist to Hip Ratio|*Anthropometry|Body Mass Index|Polymorphism, Single Nucleotide|Transcription Factor 7-Like 2 Protein|Genetic Predisposition to Disease|Genetic Loci|African Continental Ancestry Group|Linkage Disequilibrium|European Continental Ancestry Group|Allele Frequency|Ethnic Groups|HABP2 protein, human|Serine Endopeptidases 63 IRX4 28336264 J Pediatr (Rio J) 2017 10.1016/j.jped.2016.11.007 6 0 0 60 Humans|Heart Defects, Congenital|Comparative Genomic Hybridization|DNA Copy Number Variations|22q11.2 Deletion Syndrome|Chromosome Deletion|*Genomics|Multiplex Polymerase Chain Reaction 63 IRX4 28110125 Stem Cell Res 2017 10.1016/j.scr.2017.01.006 8 2 0 60 Humans|*Myocytes, Cardiac|Reproducibility of Results|*Atrial Fibrillation|*Pluripotent Stem Cells|Human Induced Pluripotent Stem Cells|Cell Differentiation|*Heart Atria|Cell Culture Techniques|Cell Line|Heart Ventricles|Cells, Cultured|Culture Media|*Albumins 63 ISL2 29066954 Front Neural Circuits 2017 PMC5641327 10.3389/fncir.2017.00073 4 0 0 74 *Superior Colliculi|Visual Pathways|Retinal Ganglion Cell|Retina|LIM-Homeodomain Proteins|Transcription Factors 55 ISL2 28473875 Clin Epigenetics 2017 PMC5415776 10.1186/s13148-017-0344-4 5 3 0 74 Humans|*DNA Methylation|*B-DNA|*Obesity|*Adipose Tissue|CpG Islands|Weight Loss|Epigenesis, Genetic|Gastric Bypass|Subcutaneous Fat|Promoter Regions, Genetic|Adipose Tissue, White|Genome-Wide Association Study|Genome, Human 55 ISL2 28078709 J. Comp. Neurol. 2017 10.1002/cne.24172 0 0 0 74 Mice|Animals|*Retinal Ganglion Cells|*Transcription Factors|Retina|Visual Pathways|Axons|Mice, Inbred C57BL 55 ISM1 28093041 Reprod Sci 2017 10.1177/1933719116687653 5 0 0 121 Humans|Female|*Prospective Studies|*Oocytes|*Embryonic Development|Blastocyst|Embryo Culture Techniques|Embryo Transfer|Fertilization in Vitro|Culture Media|Fertilization|*Sibling 26 isx 29073082 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5664558 10.1073/pnas.1714963114 7 0 0 94 beta-Carotene 15,15'-Monooxygenase|Vitamin A|*Diet|beta Carotene|Retinoic Acid|Isx protein, human|Transcription Factor|Carotene|Homeodomain Proteins|Lipid Metabolism|Retinaldehyde|Intestinal Epithelium|Gene Expression Regulation|*Complement Factor B|3'-(1-butylphosphoryl)adenosine 76 ITIH5 29190932 Oncotarget 2017 PMC5696198 10.18632/oncotarget.21426 4 8 0 60 Humans|*Neoplastic Cells, Circulating|*Progression-Free Survival|Prospective Studies|Disease-Free Survival|Biomarkers, Tumor|DNA Methylation|Promoter Regions, Genetic|*Cell Count 37 ITIH5 29150847 Br. J. Dermatol. 2017 10.1111/bjd.16129 2 2 0 60 Humans|*Acetylation|*Histones|*Sunlight|*Protein Processing, Post-Translational|Histone Acetyltransferases|Epigenesis, Genetic|Histone-Lysine N-Methyltransferase|Histone Deacetylases|*Skin|RNA, Messenger 37 ITIH5 28940371 Mol. Carcinog. 2017 10.1002/mc.22742 2 1 0 60 Humans|*Endoglin|DNA Methylation|Promoter Regions, Genetic|*Signal Transduction|Inactivation, Gene|Prognosis|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Proteinase Inhibitory Proteins, Secretory|Downregulation|Cell Line, Tumor|recombinant human bone morphogenetic protein-2|Transforming Growth Factor beta|Bone Morphogenetic Protein 2|ITIH5 protein, human 37 ITIH5 28289921 Clin. Exp. Metastasis 2017 PMC5450640 10.1007/s10585-017-9840-3 3 8 0 60 Humans|Mice|Animals|*RNA Interference|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Cell Movement|Gene Expression Regulation, Neoplastic|Liver Neoplasms|Prognosis|Cell Proliferation|Mice, Nude|Pancreas|Biomarkers, Tumor|Xenograft Model Antitumor Assays|Lung Neoplasms|Tumor Cells, Cultured|shRNA|Apoptosis|Survival Rate 37 ITIH5 28231808 Mol. Cancer 2017 PMC5322623 10.1186/s12943-017-0610-2 2 32 0 60 DNA Methylation|Genes, Tumor Suppressor|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Proteinase Inhibitory Proteins, Secretory|Biomarkers, Tumor|*Epigenetic|Down-Regulation|Cell Line, Tumor|Carcinogenesis|Disease Progression|RNA, Messenger|Epigenesis, Genetic 37 ITIH5 28059468 Mol. Carcinog. 2017 10.1002/mc.22613 1 4 0 60 Humans|Female|*Cervix Uteri|HeLa Cells|*Carcinogenesis|Promoter Regions, Genetic|DNA Methylation|Gene Silencing|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Downregulation|Biomarkers, Tumor|Proteinase Inhibitory Proteins, Secretory|Cervical Intraepithelial Neoplasia|Cervical Cancer|mRNA|Cell Line, Tumor|Disease Progression|Genes, Tumor Suppressor|Genomics 37 ITM2A 28872940 Adipocyte 2017 PMC5736245 10.1080/21623945.2017.1362510 0 4 0 90 Mice|Animals|*Lamin Type A|*3T3-L1 Cells|Familial Partial Lipodystrophy|*Cell Differentiation|Adipogenesis|Adipocytes|Mutations|Adipose Tissue|Phenotype|Fibroblasts|Lipid Metabolism|Upregulation 47 ITM2A 28415601 Oncotarget 2017 PMC5482637 10.18632/oncotarget.16424 4 6 0 90 Child|Humans|Epigenesis, Genetic|GATA3 protein, human|*GATA3 Transcription Factor|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Genome Wide Association Analysis|SNPs|Genetic Predisposition to Disease|STAT4 Transcription Factor|Gene Expression|ITM2A protein, human|Membrane Proteins 47 ITM2A 28247205 Apoptosis 2017 10.1007/s10495-017-1357-3 1 2 0 90 Humans|cytolethal distending toxin|*Jurkat Cells|*Aggregatibacter actinomycetemcomitans|*Bacterial Toxins|cytolethal distending toxin, Actinobacillus actinomycetemcomitans|*Apoptosis|Cell Membrane|Protein Subunits 47 KCNT2 29069600 Cell Rep 2017 PMC5687820 10.1016/j.celrep.2017.09.088 5 4 0 55 Humans|Cricetinae|Animals|*Potassium|*Sodium Channel Activators|*Potassium Channels, Sodium-Activated|Infantile Epileptic-Dyskinetic Encephalopathy|Spasms, Infantile|Potassium Channels|Action Potentials|Cricetulus|Mutation|Nerve Tissue Proteins|Mutation, Missense|Heterozygote|Neurons|CHO Cells|KCNT2 protein, human 56 KCNT2 28943756 J Exp Neurosci 2017 PMC5602212 10.1177/1179069517726996 3 15 0 55 *Hyperalgesia|*Nociceptors|*Potassium Channels, Sodium-Activated|Ganglia, Spinal|Membrane Potentials|Neurons 56 KCNT2 28600454 Biochem. J. 2017 PMC5568769 10.1042/BCJ20160623 8 1 0 55 Ischemic Preconditioning, Myocardial|Mitochondria, Heart|mitochondrial permeability transition pore|Mitochondrial Membrane Transport Proteins|Myocardial Reperfusion Injury|Potassium Channels|Diazoxide|Cardiotonic Agents|Potassium Channel Blockers|Myocardial Ischemia|Myocytes, Cardiac 56 KCNT2 28498492 J. Comp. Neurol. 2017 10.1002/cne.24238 3 1 0 55 Animals|Mice|*Mossy Fibers, Hippocampal|afadin|*Synapses|*Microfilament Proteins|NECTIN1 protein, human|Nectin-1|Presynaptic Terminals|Pyramidal Cells|Dendrites|N-Cadherin|Hippocampus|Postsynaptic Densities|Cell Adhesion Molecules|*Morphogenesis 56 KCNT2 28222129 PLoS ONE 2017 PMC5319697 10.1371/journal.pone.0169914 3 5 0 55 Animals|*Cell Volume|Potassium Channels|Membrane Potentials|Patch-Clamp Techniques|Nerve Tissue Proteins|Xenopus laevis|Oocytes|Neurons|Potassium Channels, Sodium-Activated|Aquaporin 1|mRNA 56 KCTD12 29242380 Mol. Cell Proteomics 2017 PMC5836374 10.1074/mcp.RA117.000267 11 0 0 183 *Gastrointestinal Stromal Tumors|*Proteome|*Exosomes|Proteomics|Neoplasm Recurrence, Local|Imatinib Mesylate|Proto-Oncogene Proteins c-kit|Pyrimidines|Drug Resistance, Neoplasm|Piperazines|Benzamides|Antineoplastic Agents|Cell Line, Tumor|Biomarkers 55 KCTD12 29106983 Neuropharmacology 2017 10.1016/j.neuropharm.2017.10.033 1 1 0 183 Receptors, GABA-B|Potassium Channels|Neurons 55 KCTD12 28869606 Oncogene 2017 PMC5671937 10.1038/onc.2017.287 11 42 0 183 Humans|Mice|Animals|*Cyclin-Dependent Kinase 1|AURKA protein, human|*Aurora Kinase A|*Genes, cdc|Phosphorylation|cdc25 Phosphatases|Cell Cycle|G2 Phase|Mitosis|*Cell Transformation, Neoplastic|S Phase|*Tumorigenesis|Serine|HeLa Cells|KCTD12 protein, human|Proteins|CDC25B protein, human|CDK1 protein, human 55 KCTD12 28713569 Pharmacol Res Perspect 2017 PMC5508304 10.1002/prp2.319 2 19 0 183 Animals|Cricetinae|*GABA-B Receptor|G Protein-Coupled Inwardly-Rectifying Potassium Channels|Cricetulus|Hippocampus|CHO Cells|gamma-Aminobutyric Acid 55 KCTD12 28448578 PLoS Genet. 2017 PMC5407610 10.1371/journal.pgen.1006675 20 0 0 183 Humans|Tibet|Haplotypes|Natural Selection|Altitude|*Biological Evolution|Acclimatization|Hypoxia-Inducible Factor-Proline Dioxygenases|endothelial PAS domain-containing protein 1|Basic Helix-Loop-Helix Transcription Factors|Asian Continental Ancestry Group|Adaptation, Physiological|*Sequencing, Whole Genome|Polymorphism, Single Nucleotide|Hypoxia|Gene Flow|Genome|KCTD12 protein, human|Proteins 55 KCTD12 28062797 Mol. Cell Proteomics 2017 PMC5341002 10.1074/mcp.M116.062273 11 31 0 183 Humans|*Proteomics|Adenoma|Colorectal Neoplasms|Biomarkers, Tumor|*Cell Transformation, Neoplastic|*Tumorigenesis|Chromatography, Liquid|Mass Spectrometry|Gene Expression Regulation, Neoplastic|Adenocarcinoma|Up-Regulation|Cohort Studies 55 KIAA0196 28915599 Oncotarget 2017 PMC5593570 10.18632/oncotarget.17657 4 2 0 71 Humans|*Cystectomy|*DNA Copy Number Variations|*Urinary Bladder|*Cell Free DNA|*Prospective Studies|*Carcinoma, Transitional Cell|*Urinary Bladder Neoplasms|Multiplex Ligation-Dependent Probe Amplification 35 KIAA0196 28878906 Clin Case Rep 2017 PMC5582219 10.1002/ccr3.1080 2 0 0 71 Humans|Spastic Paraplegia Type 8|*Spastic Paraplegia, Hereditary|Poland|*Paraplegia|KIAA0196 protein, human|Proteins|Mutation|Pedigree|Phenotype 35 KIAA0196 28551275 Neurobiol. Aging 2017 10.1016/j.neurobiolaging.2017.04.023 1 1 0 71 Humans|Amyotrophic Lateral Sclerosis 2, Juvenile|VCP protein, human|*Valosin-Containing Protein|*Frontotemporal Dementia|Amyotrophic Lateral Sclerosis|Amyotrophic lateral sclerosis 1|Frontotemporal Lobar Degeneration|*Genetic Testing|Mutations|KIAA0196 protein, human|*Cohort Studies|Genetic Predisposition to Disease|Cell Cycle Proteins|Adenosine Triphosphatases|C9orf72 protein, human|C9orf72 Protein 35 KLF16 28714951 Nat. Neurosci. 2017 PMC5672813 10.1038/nn.4598 53 6 0 93 *Autism Spectrum Disorder|*Mutations|Exome|Genetic Predisposition to Disease|Exons|Mutation, Missense|Gene Expression 26 KLF16 28670390 Am J Transl Res 2017 PMC5489902 2 2 0 93 Humans|*Stomach Neoplasms|*Stomach|Kruppel-Like Transcription Factors|Prognosis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Up-Regulation|Lymphatic Metastasis|Cell Line, Tumor|Transcriptional Activation|Immunohistochemistry|Signal Transduction|mRNA|CDK4 protein, human|Cyclin-Dependent Kinase 4 26 KLF8 28986741 Pathol. Oncol. Res. 2017 10.1007/s12253-017-0321-4 4 1 0 370 Humans|*Carcinoma, Non-Small-Cell Lung|*Factor VIII|*Lung Neoplasms|CDH1 protein, human|E Cadherin|Vimentin|Epithelial-Mesenchymal Transition|Antigens, CD|Prognosis|Adenocarcinoma|Lymphatic Metastasis|Biomarkers, Tumor|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Cell Movement|Immunohistochemistry|KLF8 protein, human|Repressor Proteins 102 KLF8 28943967 Oncol Lett 2017 PMC5594250 10.3892/ol.2017.6734 6 5 0 370 Humans|*Transcriptional Activation|*Factor VIII|*Epithelial-Mesenchymal Transition|*Transcription Factors|Neoplasm Invasiveness|Repressor Proteins|*Pancreatic Cancer|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Signal Transduction|Cell Movement|Tumorigenesis|*Pancreas|*Neoplastic Processes|Cell Transformation, Neoplastic|Cell Line, Tumor|KLF8 protein, human 102 KLF8 28842254 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.08.074 10 5 0 370 *Lung Adenocarcinoma|Lung Cancer|MicroRNAs|Adenocarcinoma|Neoplasm Invasiveness|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Cell Line, Tumor|Prognosis|*Neoplastic Processes|Lung 102 KLK15 29273476 J. Hepatol. 2017 10.1016/j.jhep.2017.11.040 25 1 0 19 Mice|Humans|Animals|*Nonalcoholic Steatohepatitis|*Pyroptosis|Choline Deficiency|Liver|Mice, Inbred C57BL|Methionine|NF-kappa B|Inflammation|Disease Models, Animal|Apoptosis|Up-Regulation|GSDMD protein, human|Neoplasm Proteins 53 KLK15 29095848 PLoS ONE 2017 PMC5667830 10.1371/journal.pone.0186847 5 1 0 19 Humans|Female|*Cystadenocarcinoma, Serous|*Ovarian Cancer|KLK15 protein, human|Kallikreins|Carcinoma, Ovarian Epithelial|Prognosis|Cancer Biomarkers|Gene Expression Regulation, Neoplastic|mRNA|Progression-Free Survival|trypsin-like serine protease|Real-Time Polymerase Chain Reaction|Ovary|Cohort Studies|KLK10 protein, human|Humans|Female|*Cystadenocarcinoma, Serous|*Ovarian Cancer|KLK15 protein, human|Kallikreins|Carcinoma, Ovarian Epithelial|Prognosis|Cancer Biomarkers|Gene Expression Regulation, Neoplastic|mRNA|Progression-Free Survival|trypsin-like serine protease|Real-Time Polymerase Chain Reaction|Ovary|Cohort Studies|KLK10 protein, human 53 KLK9 29095848 PLoS ONE 2017 PMC5667830 10.1371/journal.pone.0186847 5 1 0 20 Humans|Female|*Cystadenocarcinoma, Serous|*Ovarian Cancer|KLK15 protein, human|Kallikreins|Carcinoma, Ovarian Epithelial|Prognosis|Cancer Biomarkers|Gene Expression Regulation, Neoplastic|mRNA|Progression-Free Survival|trypsin-like serine protease|Real-Time Polymerase Chain Reaction|Ovary|Cohort Studies|KLK10 protein, human|Humans|Female|*Cystadenocarcinoma, Serous|*Ovarian Cancer|KLK15 protein, human|Kallikreins|Carcinoma, Ovarian Epithelial|Prognosis|Cancer Biomarkers|Gene Expression Regulation, Neoplastic|mRNA|Progression-Free Survival|trypsin-like serine protease|Real-Time Polymerase Chain Reaction|Ovary|Cohort Studies|KLK10 protein, human 36 KLK9 29229980 Sci Rep 2017 PMC5725587 10.1038/s41598-017-16269-6 4 1 0 20 Humans|*Sequencing, Next-Generation|kallikrein 5, human|*Kallikreins|*Cloning, Molecular|Alternative Splicing|Sequence Analysis, DNA|Bioinformatic|Exons|Cell Line, Tumor|Nested PCR|RNA, Messenger|KLK6 protein, human 36 KLK9 28559305 Biochem. J. 2017 10.1042/BCJ20170174 0 1 0 20 Humans|*Tissue Kallikreins|Kallikrein B'|Substrate Specificity|Kinetics|Serine Proteinase Inhibitors|Amino Acid Sequence|Glycosylation 36 KLK9 28115917 Clin Proteomics 2017 PMC5241945 10.1186/s12014-017-9140-6 0 8 0 20 Humans|*Enzyme-Linked Immunosorbent Assay|Kallikrein B'|Recombinant Proteins|Antibodies, Monoclonal 36 KLLN 29024157 Mol. Reprod. Dev. 2017 10.1002/mrd.22923 1 4 0 121 Male|Mice|Animals|*Spermatogonia|nonylphenol|p73 protein, human|Tumor Protein p73|Downregulation|*Phenols|Apoptosis|killin protein, human|Tumor Suppressor Proteins|3' Untranslated Region|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation|*Reproduction 31 KLLN 28755140 Endocrine 2017 10.1007/s12020-017-1368-4 6 1 0 121 Humans|*Thyroid Cancer, Papillary|Carcinoma, Papillary|Thyroid Neoplasms|Thyroid Gland|Goiter, Nodular|PTEN protein, human|*PTEN Phosphohydrolase|Carcinoma|Cowden Syndrome|Biomarkers, Tumor|Promoter Regions, Genetic|Case-Control Studies 31 KLLN 28484590 Clin Sarcoma Res 2017 PMC5418758 10.1186/s13569-017-0075-5 6 1 0 121 *Histones|Giant Cell Tumor of Bone|*Osteosarcomas|Chondroblastomas|Bone Neoplasms|*Mutations|Immunohistochemistry|Biomarkers, Tumor 31 KLLN 28069272 Pathol. Res. Pract. 2017 10.1016/j.prp.2016.10.012 0 1 0 121 Humans|Male|Female|Adult|Middle Aged|Aged|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|SMARCB1 protein, human|*SMARCB1 Protein|*Carcinomas|Maxillary Sinus Neoplasms|Immunohistochemistry|*Genes, cdc|Biomarkers, Tumor|DNA Methylation|*Genes, ras|Genes, p16|RASSF1 protein, human|Tumor Suppressor Proteins 31 KLRC4 28706259 Sci Rep 2017 PMC5509750 10.1038/s41598-017-05877-x 1 0 0 16 Humans|*Receptors, C-Type Lectin|*Asian Continental Ancestry Group|*Behcet Disease|SNPs|Genetic Predisposition to Disease|Allele|Restriction Fragment Length Polymorphism|Gene Frequency|Genotype|Uveomeningoencephalitic Syndrome|Case-Control Studies|Real Time PCR 24 LACRT 28419103 PLoS ONE 2017 PMC5395154 10.1371/journal.pone.0175274 0 5 0 69 *Graves Ophthalmopathy|*Graves Disease|*Tear|*Biomarkers|*Proteins|Eye|Case-Control Studies|*Lacerations 27 LAD1 28803494 Epigenomics 2017 10.2217/epi-2017-0040 6 10 0 596 Humans|*Carcinoma, Renal Cell|*Prognosis|*DNA Methylation|*B-DNA|Kidney Neoplasms|CpG Islands|Promoter Regions, Genetic|Biomarkers, Tumor 84 LAD1 28731711 J. Proteome Res. 2017 PMC6339813 10.1021/acs.jproteome.7b00245 5 1 0 596 *Proteomics|Early Detection of Cancer|*Lung Adenocarcinoma|*Multiple Pulmonary Nodules|Lung Cancer|Adenocarcinomas|Solitary Pulmonary Nodule|Biomarkers, Tumor|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|CEACAM6 protein, human|Cell Adhesion Molecules|Antigens, CD|GPI-Linked Proteins|Chromatography, Liquid 84 LAD1 28328326 N. Engl. J. Med. 2017 PMC5494261 10.1056/NEJMoa1612197 24 6 0 596 Humans|Mice|Animals|*Interleukin-23|*Interleukin 12|Leukocyte adhesion deficiency type 1|Ustekinumab|*Leukocyte-Adhesion Deficiency Syndrome|IL23A protein, human|*Interleukin-23 Subunit p19|IL17A protein, human|Interleukin-17|Antibodies, Monoclonal|Crohn Disease|Antibodies, Monoclonal, Humanized|Periodontitis 84 laptm5 29038051 Biochim Biophys Acta Mol Basis Dis 2017 PMC5714325 10.1016/j.bbadis.2017.10.018 7 1 0 113 Humans|Male|Female|Animals|Mice|Amyloid Plaques|ApoE4|Alzheimer Disease|Apolipoproteins E|Amyloid beta-Peptides|Amyloid beta-Protein Precursor|*Genotype|Mice, Transgenic|Disease Models, Animal|Brain|Microglia|Allele|Phenotype|Networks, Gene|*Diet|LAPTM5 protein, human|Membrane Proteins 49 laptm5 28464033 PLoS ONE 2017 PMC5413007 10.1371/journal.pone.0176544 2 32 0 113 Humans|*HeLa Cells|*Down-Regulation|*Apoptosis|*Mitochondria|bcl-2 Homologous Antagonist-Killer Protein|Caspases|LAPTM5 protein, human|*Membrane Proteins|*Lysosome|Proto-Oncogene Proteins c-bcl-2|Apoptosis Regulatory Proteins|CASP9 protein, human|Caspase 9|Bcl-2-Like Protein 11|bcl-X Protein|Myeloid Cell Leukemia Sequence 1 Protein|Jurkat Cells|Caspase Inhibitors 49 laptm5 28097442 J. Neurooncol. 2017 10.1007/s11060-017-2369-0 6 0 0 113 Humans|*Glioblastoma|*Prognosis|DNA Modification Methylases|DNA Repair Enzymes|Temozolomide|Brain Neoplasms|Dacarbazine|Tumor Suppressor Proteins|Antineoplastic Agents, Alkylating|DNA Methylation|Promoter Regions, Genetic|Biomarkers, Tumor|Disease-Free Survival|Glioma|Retrospective Studies|LAPTM4B protein, human|Membrane Proteins|Oncogene Proteins 49 LARP6 28400296 Protein Expr. Purif. 2017 PMC5546403 10.1016/j.pep.2017.04.004 1 3 0 495 Animals|*Models, Genetic|Zebrafish|Zebrafish Proteins|*RNA-Binding Proteins|Platyfish|Amino Acid Sequence|Protein Biosynthesis|Phylogeny|Cloning, Molecular|Recombinant Proteins|RNA 35 LARP6 28344782 Cilia 2017 PMC5364628 10.1186/s13630-017-0047-7 2 19 0 495 Ribonucleoproteins|mRNA|Type I Collagen|Cilia|Autoantigens|Protein Binding|RNA Binding Protein|*Ku Autoantigen|*Hematopoiesis 35 LARP6 28240345 Australas. J. Dermatol. 2017 10.1111/ajd.12604 3 0 0 495 Humans|*Collagen Type I|*RNA Recognition Motif|*Upregulation|*Infrared Rays|Ribonucleoproteins|*Transcriptional Activation|Gene Expression|*Epidermis|*Microarray Analysis|Autoantigens|RNA, Messenger|Protein Binding|*Phototherapy 35 LARP6 28211947 Dev. Growth Differ. 2017 10.1111/dgd.12342 4 6 0 495 Mice|Animals|*Osteogenesis|*Collagen Type I|IGF1 protein, human|*Insulin-Like Growth Factor I|*Binding Protein|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|*Cell Differentiation|Osteoblasts|Osteocalcin|Bone Morphogenetic Protein 2|Alkaline Phosphatase|mRNA|siRNA|Cells, Cultured|Cell Line 35 LARP6 28112218 Sci Rep 2017 PMC5255556 10.1038/srep41173 6 40 0 495 *Collagen Type I|*Phosphorylation|*mTORC1|Ribonucleoproteins|mRNA|RNA-Binding Proteins|Autoantigens|Protein Binding|Collagen|Cells, Cultured|Endoplasmic Reticulum 35 LBX2 28592888 Leukemia 2017 10.1038/leu.2017.176 11 1 0 16 Adult|Humans|Proteins, Homeotic|T-ALL|Receptors, Antigen, T-Cell, gamma-delta|Leukemia-Lymphoma, Adult T-Cell|Cell Differentiation|BARX2 protein, human 34 LBX2 28098899 Oncol. Rep. 2017 10.3892/or.2017.5380 3 0 0 16 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Transcriptome|Neoplasm Staging|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Prognosis|Oligonucleotide Array Sequence Analysis|Protein Interaction Maps|Gene Regulatory Networks|Lung|Computational Biology|RNA, Messenger|Real-Time Polymerase Chain Reaction|*Biological Phenomena 34 LGALS12 29098769 IUBMB Life 2017 10.1002/iub.1690 1 2 0 461 *Galectin|*Promoter Regions, Genetic|*Colorectal Cancer|DNA Methylation|Epigenesis, Genetic|*Epigenetic|CpG Islands|Azacitidine|Cell Proliferation|Decitabine|Gene Expression Regulation, Neoplastic|Acetylation|Histones|Cell Movement|Downregulation|Histone Deacetylase Inhibitors|Genes, Tumor Suppressor|Cell Line, Tumor 24 LGALS12 28812028 J Diabetes Res 2017 PMC5547755 10.1155/2017/2180819 3 12 0 461 Humans|*Diabetes Mellitus, Type 2|*Blood Glucose|Hypoglycemic Agents|Hyperglycemia 24 LHX5 28516904 Nat Commun 2017 PMC5454373 10.1038/ncomms15079 5 19 0 58 Mice|Animals|*Purkinje Cells|Cerebellum|Dendrites|Dendritic Spines|*Morphogenesis|Synapses|Neurogenesis|Nerve Tissue Proteins|Actin Cytoskeleton|F-Actin|Lhx1 protein, mouse|Transcription Factors|LIM-Homeodomain Proteins 61 LIM2 29168146 Cardiovasc Eng Technol 2017 10.1007/s13239-017-0337-7 0 0 0 80 Humans|Swine|Animals|*Mitral Valve|Mitral Valve Annuloplasty|Heart Valve Prosthesis|Mitral Valve Insufficiency|Heart Valve Prosthesis Implantation|Prosthesis Design|*Tricuspid Valve|Echocardiography|Treatment Outcome 116 LIM2 28302169 BMC Endocr Disord 2017 PMC5356396 10.1186/s12902-017-0164-8 3 11 0 80 Humans|Combined Pituitary Hormone Deficiency|*Hypopituitarism|LIM-Homeodomain Proteins|Winkelman Bethge Pfeiffer syndrome|*Hearing Loss, Sensorineural|Homeodomain Proteins|Pituitary Hormones|Transcription Factors|Mutations|Pituitary Hormones, Anterior|Pedigree|*Muscle Rigidity|Isoforms 116 LIM2 28055976 Oncotarget 2017 PMC5355253 10.18632/oncotarget.14406 6 2 0 80 Humans|*Prognosis|*Brain Neoplasms|Glioma|AC133 Antigen|Neoplastic Stem Cells|Neoplasm Grading|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Hox Genes|Downregulation|HOXA10 protein, human|Homeobox A10 Proteins 116 LIMA1 28465438 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5441781 10.1073/pnas.1619356114 4 3 0 489 Humans|*Actins|*Phosphoric Monoester Hydrolases|Cytoskeletal Proteins|Phosphorylation|CDC2 Protein Kinase|HeLa Cells|*Biochemical Phenomena|CDC14A protein, human 43 LIMA1 28093207 Cancer Lett. 2017 10.1016/j.canlet.2016.12.034 2 6 0 489 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|Gene Expression Regulation, Neoplastic|Tumor Suppressor Proteins|nutlin 3|Piperazines|Cell Line, Tumor|Imidazoles|*Neoplastic Processes|Downregulation|cDNA Microarray|Prognosis|Apoptosis|Cell Proliferation|Cell Cycle Arrest|Cell Death|Neoplasm Invasiveness|LIMA1 protein, human 43 LINC00958 29050779 Gynecol. Oncol. 2017 10.1016/j.ygyno.2017.10.006 15 0 0 0 Humans|Female|*RNA, Long Noncoding|*Transcriptome|*Endometrial Cancer|Sequence Analysis, RNA|Gene Expression Profiling|Gene Expression Regulation, Neoplastic 21 Lingo2 29036934 Int J Environ Res Public Health 2017 PMC5664729 10.3390/ijerph14101228 1 0 0 36 Humans|Female|Pregnancy|*Risk Factors|Venous Thromboembolism|Genome-Wide Association Study|Genetic Predisposition to Disease|Case-Control Studies|Polymorphism, Single Nucleotide|Pregnancy Complications, Cardiovascular|*Epistasis, Genetic|Postpartum 31 Lingo2 28973307 Hum. Mol. Genet. 2017 PMC5886256 10.1093/hmg/ddx340 1 0 0 36 Genome-Wide Association Study|*Neuroticism|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Genetic Predisposition to Disease|Genotype|Schizophrenia|Parkinson Disease 31 LMTK2 29090275 Biochem Biophys Rep 2017 PMC5645172 10.1016/j.bbrep.2017.09.006 3 41 0 253 Animals|Male|Humans|*TYK2 Kinase|*Lemur|*Response Element|LMTK2 protein, human|Transcription, Genetic|Signal Transduction|Tetradecanoylphorbol Acetate|Promoter Regions, Genetic|Protein Kinase C|*Membrane Proteins|Transcription Factor AP-1|RNA, Messenger|Transfection 47 LMTK2 28040547 Cancer Lett. 2017 10.1016/j.canlet.2016.12.025 8 3 0 253 Animals|*Lemur|*TYK2 Kinase|Glycogen Synthase Kinase 3|*Apoptosis|Anti-Apoptotic Proteins|Proteins, BCL2|Protein, BIM|*Serine Threonine Kinase|Myeloid Cell Leukemia Sequence 1 Protein|Proto-Oncogene Proteins|TNF-Related Apoptosis-Inducing Ligand|Membrane Proteins|Downregulation|Cell Line, Tumor|Antineoplastic Agents|RNA, Small Interfering|RNA Interference 47 LPHN2 28972101 J. Cell Biol. 2017 PMC5674891 10.1083/jcb.201703042 23 6 0 177 Mice|Animals|alpha-latrotoxin receptor|*Hippocampus|*Receptors, Peptide|Region, Hippocampal CA1|Synapses|Entorhinal Cortex|Pyramidal Cells|Dendritic Spines|Neurons|Presynaptic Terminals|Memory|*Recognition, Psychology|Mice, Knockout|*Neurogenesis|Receptors, G-Protein-Coupled 29 LPHN2 28768912 JCI Insight 2017 PMC5543912 10.1172/jci.insight.95063 3 0 0 177 Animals|Mice|Endothelial Cells|Experimental Autoimmune Encephalomyelitis|Microglia|Th17 Cells|*B-Lymphocytes|Spinal Cord|Multiple Sclerosis|Macrophages|Myeloid Cells|Inflammation 29 LPHN2 28657541 Aging (Albany NY) 2017 PMC5509457 10.18632/aging.101254 64 9 0 177 *Stomach Neoplasms|*RNA, Circular|Neoplasm Recurrence, Local|*Cell Proliferation|*Downregulation|miRNA|Gene Expression Regulation, Neoplastic|*Cell Cycle|mRNA|Upregulation|Cell Line, Tumor|Biomarkers, Tumor|Gene Expression Profiling|Signal Transduction|Transfection 29 LPHN2 28459279 Am. J. Respir. Cell Mol. Biol. 2017 PMC5650084 10.1165/rcmb.2016-0284OC 9 0 0 177 Humans|Pulmonary Emphysema|alpha-1-Antitrypsin Deficiency, Autosomal Recessive|*alpha 1-Antitrypsin Deficiency|Lung|Chronic Obstructive Pulmonary Disease|*Genomics|Gene Expression Profiling|Gene Expression Regulation|mRNA|Cells, Epithelial|Biomarkers 29 LRIG3 29246624 J. Neurol. Sci. 2017 10.1016/j.jns.2017.10.025 0 0 0 135 Humans|TYRP1 protein, human|*Membrane Glycoproteins|*Glioma|Integral Membrane Proteins|Genes, Tumor Suppressor|Signal Transduction|Oncogenesis|Cell Proliferation|LRIG1 protein, human 50 LRIG3 28851705 Development 2017 PMC5612249 10.1242/dev.144519 4 1 0 135 Mice|Animals|NTN1 protein, human|*Netrin-1|*Chickens|Semicircular Canals|Morphogenesis|Epithelium|Gene Expression Regulation, Developmental|Nerve Growth Factors|*Organogenesis|Tumor Suppressor Proteins|*Embryonic Development|Basement Membrane|In Situ Hybridization 50 LRIG3 28841699 PLoS ONE 2017 PMC5571912 10.1371/journal.pone.0183816 5 2 0 135 Humans|Female|*Prognosis|Membrane Glycoproteins|Genes, Tumor Suppressor|Membrane Proteins|Biomarkers, Tumor|Malignancy|*Vaginal Neoplasms|Cohort Studies 50 LRIG3 28465216 Pharmacol. Res. 2017 10.1016/j.phrs.2017.04.022 9 0 0 135 Humans|Adult|United States|*Carcinoma, Non-Small-Cell Lung|ROS1 protein, human|*Protein-Tyrosine Kinases|*Proto-Oncogene Proteins|*Lung Cancers|*Tyrosine|*Protein Kinase Inhibitors|Crizotinib|Receptor Protein-Tyrosine Kinases|cabozantinib|Pyridines|Anaplastic Lymphoma Kinase|Anilides|*Oncogenes|lorlatinib|Lactams, Macrocyclic|Proteins, Oncogene Fusion|Pyrazoles 50 LRRC26 28416688 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5422807 10.1073/pnas.1703081114 11 0 0 54 *Large-Conductance Calcium-Activated Potassium Channels|Ion Channel Gating|Membrane Potentials|Neoplasm Proteins|Calcium|*Cells, Epithelial|*Cell Count|*Biological Transport 29 LRRC26 28292889 Physiol Rep 2017 PMC5350182 10.14814/phy2.13179 1 4 0 54 Animals|*Colon|Large-Conductance Calcium-Activated Potassium Channel beta Subunits|Large-Conductance Calcium-Activated Potassium Channel alpha Subunits|Aldosterone|Potassium 29 LRWD1 28778956 EMBO J. 2017 PMC5599798 10.15252/embj.201796541 10 3 0 85 Animals|*Heterochromatin|*Methylation|*Histones|KMT5A protein, human|Protein Lysine Methyltransferase|*Protein Processing, Post-Translational|Lysine|Replication Origins|DNA Replication|DNA Damage 22 LRWD1 28569402 J. Cell. Biochem. 2017 10.1002/jcb.26180 1 5 0 85 Male|Humans|*Carcinoma, Embryonal|*Testicular Neoplasms|Microtubule Proteins|Centrosome|CCNE1 protein, human|Cyclin E|Spermatogenesis|Cell Cycle|Testis|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cell Line, Tumor|Spermatozoa|Gene Expression Regulation, Neoplastic|Phosphorylation|*Cell Division|*Genes, Regulator|Microtubule 22 LSG1 28344588 Front Plant Sci 2017 PMC5344897 10.3389/fpls.2017.00337 0 7 0 94 *Endoreduplication|*Plant Leaves|Arabidopsis Proteins|Arabidopsis|Gene Expression Regulation, Plant|*Cell Proliferation|Plants, Genetically Modified 26 LSG1 28179369 EMBO J. 2017 PMC5376978 10.15252/embj.201696012 23 2 0 94 Cryoelectron Microscopy|Ribosome Subunits, Large, Eukaryotic|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Ribosomal Proteins|Ribosome|RNA, Ribosomal|RNA-Binding Proteins|GTPase|Protein Biosynthesis|Protein Binding|Models, Molecular|NMD3 protein, S cerevisiae 26 LSG1 28112732 Nat. Struct. Mol. Biol. 2017 PMC5555584 10.1038/nsmb.3364 28 0 0 94 Cryoelectron Microscopy|60S Ribosomal Subunit|*Ribosomes|Saccharomyces cerevisiae|Ribosomal Proteins|Saccharomyces cerevisiae Proteins|RNA, Ribosomal|Peptidyl Transferases|Export, Nuclear|*Cytosol|Models, Molecular|NMD3 protein, S cerevisiae|RNA-Binding Proteins 26 LTK 29158996 PeerJ 2017 PMC5695249 10.7717/peerj.4080 9 2 0 121 Animals|*Fish, Cichlid|*Lakes|Malawi|Melanophores|Pigmentation|Embryo, Nonmammalian|Zebrafish|*Orientation, Spatial 669 LTK 29078341 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5692561 10.1073/pnas.1710254114 13 0 0 121 Animals|ALK protein, human|*Anaplastic Lymphoma Kinase|*Zebrafish|*Tyrosine Kinase|*Ligands|LTK protein, human|*Receptor Protein-Tyrosine Kinases|Zebrafish Proteins|Amino Acid Sequence|Ltk protein, zebrafish 669 LTK 28784129 Malar. J. 2017 PMC5547577 10.1186/s12936-017-1964-z 3 1 0 121 Child|Humans|*Diagnostic Tests, Routine|Malawi|artemisinine|*Artemisinins|*Malaria|Antimalarials|Case Management|Community Health Workers|*School|*Educational Personnel|*Combined Modality Therapy|*Learning|Qualitative Research|First Aid 669 LTK 28465216 Pharmacol. Res. 2017 10.1016/j.phrs.2017.04.022 9 0 0 121 Humans|Adult|United States|*Carcinoma, Non-Small-Cell Lung|ROS1 protein, human|*Protein-Tyrosine Kinases|*Proto-Oncogene Proteins|*Lung Cancers|*Tyrosine|*Protein Kinase Inhibitors|Crizotinib|Receptor Protein-Tyrosine Kinases|cabozantinib|Pyridines|Anaplastic Lymphoma Kinase|Anilides|*Oncogenes|lorlatinib|Lactams, Macrocyclic|Proteins, Oncogene Fusion|Pyrazoles 669 Ly75 28114323 PLoS ONE 2017 PMC5256930 10.1371/journal.pone.0170652 4 1 0 198 Mice|Animals|*Mice, Inbred C57BL|*Obesity|Body Weight|Quantitative Trait Locus|*Phenotype|Chromosome Mapping|Crosses, Genetic|Body Composition|*Transcriptome Analysis|Genotype|Triglycerides|Cholesterol|Adipose Tissue, White 29 LYAR 28851297 BMC Med. Genet. 2017 PMC5575872 10.1186/s12881-017-0450-3 3 2 0 134 Humans|Fetal Hemoglobin|gamma-Globins|*Polymorphism, Genetic|beta-Thalassemia 32 LYAR 28686580 Cell Death Differ. 2017 PMC5563997 10.1038/cdd.2017.98 2 6 0 134 Humans|*Up-Regulation|*Neuroblastoma|MYCN protein, human|N-Myc Proto-Oncogene Protein|*Cell Proliferation|Oncogene Proteins|Nuclear Protein|DNA-Binding Proteins|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Line, Tumor|Chromatin Immunoprecipitation|Transfection|PRMT5 protein, human|Protein-Arginine N-Methyltransferases|LYAR protein, human 32 LYAR 28669403 Am. J. Hum. Genet. 2017 PMC5501772 10.1016/j.ajhg.2017.05.012 1 4 0 134 Adult|Humans|*Fetal Hemoglobin|gamma-Globins|*Thalassemia|beta-Thalassemia|Erythroid Progenitor Cells|Linkage Disequilibrium|Allele|Promoter Regions, Genetic|Cell Disease, Sickle|Single Nucleotide Polymorphisms|Erythropoiesis|Haplotypes|DNA-Binding Proteins|Epigenesis, Genetic|China|Thailand|PRMT5 protein, human|Protein-Arginine N-Methyltransferases 32 LYL1 29279377 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5777070 10.1073/pnas.1717125115 14 0 0 118 Child|Adult|Humans|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|*Transcriptome|Sequencing, Next-Generation|Oncogene Proteins, Fusion|Sequencing, RNA|Mutation|Gene Fusion|Base Sequence|Genomics 92 LYL1 28594911 PLoS ONE 2017 PMC5464679 10.1371/journal.pone.0179033 2 14 0 118 Mice|Humans|Animals|*Staphylococcus aureus|*Chromosomes, Human, Pair 8|*C57BL Mice|*Staphylococcus aureus Infection|Quantitative Trait Loci|Chromosome Mapping|*Bacteremia|Mice, Inbred Strains|SNPs|Chromosomes, Mammalian|Genetic Predisposition to Disease|Alleles|Gene Expression Profiling|Neutrophils 92 LYNX1 29218870 Pac Symp Biocomput 2017 PMC5728668 3 0 0 3 Adult|Child, Preschool|Humans|Animals|Mice|Adolescent|Child|*Neuroplasticity|*Neurodevelopmental Disorders|Critical Period, Psychological|Schizophrenia|Mutations|Phenotype|Brain|Epilepsy|Genomics 78 LYNX1 29206881 PLoS ONE 2017 PMC5716591 10.1371/journal.pone.0188715 3 15 0 3 Mice|Animals|*Nicotinic Receptors|Nicotine|Nicotinic Antagonists|Nicotinic Agonists|Dopamine|Dopaminergic Neurons|Mice, Transgenic|Reward|Mice, Knockout|Synaptosomes|Synaptic Transmission|Action Potentials 78 LYNX1 28101530 eNeuro 2017 PMC5241709 10.1523/ENEURO.0240-16.2016 8 2 0 3 Humans|Adolescent|Child|Dominance, Ocular|Neuroplasticity|Sensory Deprivation|Visual Cortex|Aging|*Inflammation 78 LYNX1 28100642 FASEB J. 2017 PMC5349798 10.1096/fj.201600733R 11 2 0 3 Animals|Humans|*Nicotinic Acetylcholine Receptor|*Isoforms|Protein Subunits|Acetylcholine|Xenopus laevis|Protein Binding|GPI-Linked Proteins|Oocytes|LYNX1 protein, human 78 MAGEC1 28631709 Ter. Arkh. 2017 10.17116/terarkh2017895113-117 1 0 0 33 Humans|Male|*Testis|*Oncogenes|Antigens, Neoplasm|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Repressor Proteins|*Colon Cancer|mRNA|*Testicular Neoplasms 67 MAGEC1 28631119 Pathologe 2017 10.1007/s00292-017-0311-z 0 0 0 33 Adult|Male|Humans|Adolescent|Child|*Testis|*Melanomas|Melanoma-Specific Antigens|Antigens, Neoplasm|Neoplasm Proteins|Immunohistochemistry|Biomarkers, Tumor|Membrane Proteins 67 MAGEC1 28512265 Oncotarget 2017 PMC5542247 10.18632/oncotarget.17517 8 5 0 33 Male|*Multiple Myeloma|chaetocin|*Heat Shock Protein|*Testis|Cytotoxic T-Lymphocytes|Cancer Vaccines|Immunotherapy, Adoptive|Dendritic Cells|Antigens, Neoplasm|CD8-Positive T-Lymphocytes|*Piperazines|Cross-Presentation|IL10 protein, human|IL10|Lymphocyte Activation|Immunotherapy|Cell Line, Tumor|Interferon-gamma 67 MAP3K10 28947795 Nat Commun 2017 PMC5612953 10.1038/s41467-017-00795-y 8 44 0 161 Humans|LATS1 protein, human|Protein-Serine-Threonine Kinases|Transductions, Signal|Adaptor Proteins, Signal Transducing|Phosphoproteins|Phosphorylation|Protein Binding|Transcription Factors|Hippo protein, human 61 MAP3K10 28888087 Horm Mol Biol Clin Investig 2017 PMC5790157 10.1515/hmbci-2017-0036 3 21 0 161 Humans|Animals|*Follistatin|Adipose Tissue, Brown|*Obesity|*Adiposity|Adipose Tissue, White|Thermogenesis|Bioenergetics|Uncoupling Protein 1|Diet, High-Fat|Insulin Resistance|MSTN protein, human|Myostatin|*Signal Transduction|Energy Intake|*Transforming Growth Factor 61 MAP3K10 28678312 Eur Rev Med Pharmacol Sci 2017 6 0 0 161 Mice|Animals|*MicroRNAs|*Atherosclerosis|*Signal Transduction|Apolipoproteins E|*MAP Kinase Signaling System|*Biomarkers|*Disease Progression|Inflammation|Mice, Knockout|Macrophages|Inflammation Mediators|Cytokines|Aorta 61 MAP3K10 28214207 Pathol. Res. Pract. 2017 10.1016/j.prp.2016.12.028 2 1 0 161 *Osteosarcoma|*Cell Proliferation|Bone Cancer|RNA, Micro|Gene Expression Regulation, Neoplastic|Down-Regulation|Apoptosis|Cell Line, Tumor|Cell Movement|*Cell Cycle|Real-Time Polymerase Chain Reaction 61 MAP6 29094416 Eur. J. Neurosci. 2017 PMC5765474 10.1111/ejn.13766 0 23 0 2068 Animals|Mice|Microtubule|Dynein|Microtubule-Associated Proteins|Neurons|Hippocampus|Synaptic Transmission|Cells, Cultured|Calcium Signaling|Brain|Isoforms 78 MAP6 28980356 Dev. Dyn. 2017 PMC5739964 10.1002/dvdy.24599 24 101 0 2068 Animals|*Phosphorylation|*Microtubule|Cytoskeleton|tau Proteins|Neurons|Brain|Protein Processing, Post-Translational 78 MAP6 28871106 Sci Rep 2017 PMC5583184 10.1038/s41598-017-10544-2 7 0 0 2068 Animals|Mice|*Imaging, Three-Dimensional|Diffusion Tensor Imaging|Brain|Magnetic Resonance Imaging|Brain Mapping|Mtap6 protein, mouse|*Microtubule-Associated Proteins|Diffusion Magnetic Resonance Imaging|Image Processing, Computer-Assisted|Schizophrenia 78 MAP6 28521134 Neuron 2017 10.1016/j.neuron.2017.04.042 25 2 0 2068 Animals|Chlorocebus aethiops|*Lipoylation|*Axons|*Neurons|Microtubule-Associated Proteins|Microtubules|Golgi Complex|Neurogenesis|COS Cells|Protein Transport|Secretory Vesicles 78 MAP9 29025970 J. Cell. Sci. 2017 PMC5769590 10.1242/jcs.205492 3 7 0 342 Humans|*Rhodopsin|*Cilia|*Protein Transport|ADP-Ribosylation Factors|Golgi Apparatus|trans-Golgi Network|rab GTP-Binding Proteins|GTPase-Activating Proteins|Guanine Nucleotide Exchange Factors|Protein Binding|Adaptor Proteins, Signal Transducing|*Sensory Receptor|ARF4 protein, human|GBF1 protein, human 26 MAP9 28993665 Sci Rep 2017 PMC5634483 10.1038/s41598-017-13112-w 2 8 0 342 Humans|Dogs|Animals|*Cone-Rod Dystrophies|*Retina|Electroretinography|Retinitis Pigmentosa|Retinal Cone Photoreceptor Cells|Retinal Degeneration|Leber Congenital Amaurosis|Eye Proteins|Homozygote|Pedigree|Disease Models, Animal|RPGRIP1 protein, human|Proteins 26 MAP9 28980356 Dev. Dyn. 2017 PMC5739964 10.1002/dvdy.24599 24 101 0 342 Animals|*Phosphorylation|*Microtubule|Cytoskeleton|tau Proteins|Neurons|Brain|Protein Processing, Post-Translational 26 MAP9 28539829 Int. J. Biol. Sci. 2017 PMC5441173 10.7150/ijbs.18649 2 54 0 342 Humans|*RNA Splicing|RNA Precursors|RNA-Binding Proteins|Ribonucleoproteins|*Gene Expression|Nuclear Proteins|*Protein Splicing|Exons|Carrier Proteins|*Apoptosis|RNA, Messenger|HeLa Cells|*Biochemical Phenomena 26 MATN2 28546218 Arterioscler. Thromb. Vasc. Biol. 2017 PMC5516888 10.1161/ATVBAHA.117.309021 6 68 0 125 Male|Aortic Valve Disease 1|Aortic Valve, Calcification of|*Aortic Valve|*Aortic Valve Stenosis|*Calcinosis|*Cells, Cultured|*Osteogenesis|Heart Valve Diseases|*Leydig Cells|Toll-Like Receptor 4|Signal Transduction|Myofibroblasts|Phenotype|Phosphorylation 55 MATN2 28533472 Infect. Immun. 2017 PMC5520434 10.1128/IAI.01069-16 4 3 0 125 Humans|*Yersinia pestis|*Matrilin Proteins|*Bacterial Adhesion|Spores, Bacterial|Yersinia pseudotuberculosis|Bacterial Outer Membrane Proteins|Yersinia|Type III Secretion System|*Extracellular Matrix Proteins|HeLa Cells|Protein Transport|Extracellular Matrix 55 MATN2 28416796 Nat Commun 2017 PMC5399287 10.1038/ncomms14909 14 69 0 125 *Protein-Lysine 6-Oxidase|Aminopropionitrile|EGFR protein, human|*Receptors, EGF|Signal Transduction|*Neoplastic Processes|Cell Line, Tumor|Cell Proliferation|Extracellular Matrix|Tumor Microenvironment 55 MCM9 28863940 Fertil. Steril. 2017 10.1016/j.fertnstert.2017.07.015 10 0 0 93 Humans|Female|*Menopause, Premature|*Primary Ovarian Insufficiency|*Chromosomal Instability|Minichromosome Maintenance Proteins|Exome|Pedigree|Genetic Predisposition to Disease|DNA Repair|Polymorphism, Single Nucleotide|Mutation|MCM8 protein, human 45 MCM9 28487407 Genes Dev. 2017 PMC5435893 10.1101/gad.297663.117 10 2 0 93 Humans|*DNA Replication|MCM2-7 Helicase|DNA Breaks, Double-Stranded|Homologous Recombination|RAD52 protein, human|Rad52 DNA Repair and Recombination Protein|DNA Repair|DNA Damage|Saccharomyces cerevisiae Proteins|Cell Cycle Proteins|DNA-Binding Proteins|Saccharomyces cerevisiae|DNA|MCM8 protein, human 45 MCTS1 28732596 Mol. Cell 2017 10.1016/j.molcel.2017.06.032 0 0 0 209 Animals|Humans|Cryoelectron Microscopy|Eukaryotic Initiation Factors|40S Ribosomal Subunit|Ribosomes|Peptide Chain Initiation, Translational|Start Codon|Protein Biosynthesis|mRNA|Protein Conformation|MCTS1 protein, human|Cell Cycle Proteins|Oncogene Proteins|tRNA, Initiator|Eukaryotic Initiation Factor-2|Crystallography, Xray|Models, Molecular|Open Reading Frames 66 MCTS1 28723557 Cell Rep 2017 PMC5551485 10.1016/j.celrep.2017.06.025 13 9 0 209 Humans|*Ribosome|EIF1 protein, human|Eukaryotic Initiation Factors|MCTS1 protein, human|*Oncogene Proteins|*Cell Cycle Proteins|Protein Biosynthesis|mRNA|Neoplasm Proteins|Open Reading Frames|Binding Site|Nerve Tissue Proteins 66 MCTS1 28623304 Sci Rep 2017 PMC5473865 10.1038/s41598-017-03949-6 10 5 0 209 Animals|Humans|MCTS1 protein, human|Oncogene Proteins|Cell Cycle Proteins|Eukaryotic Initiation Factors|Peptide Chain Initiation, Translational|Open Reading Frames|Ribosomes|RNA, Messenger|Genes, cdc|Drosophila 66 MCTS1 28260082 Oncol. Rep. 2017 PMC5367364 10.3892/or.2017.5479 0 1 0 209 *Cancer-Associated Fibroblasts|*Pancreas Cancer|Cell Migration|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|Fibroblasts|Cell Proliferation|Epithelial-Mesenchymal Transition|Vimentin|Cell Line, Tumor|Glycolysis|Co-culture|Oxidative Phosphorylation|Lactate Dehydrogenase|Neoplasm Invasiveness 66 MCTS1 28258651 Mol Oncol 2017 PMC5527469 10.1002/1878-0261.12048 8 12 0 209 Animals|Humans|Female|sphingosine kinase|Cell Line, Tumor|Ovarian Cancer|*Phosphotransferases (Alcohol Group Acceptor)|Glycolysis|Carcinoma, Ovarian Epithelial|Sphingosine|*Metabolomics|Gene Expression Regulation, Neoplastic|Tricarboxylic Acid Cycle|Upregulation|*Magnetic Resonance Imaging|Lactate|Mitochondria|Glucose|*Phenotype 66 megf10 29128256 Neuromuscul. Disord. 2017 10.1016/j.nmd.2017.09.017 2 0 0 113 Adult|Male|Humans|Aged|Child|*Myopathies|*Phenotypes|Connectin|*Respiratory Insufficiency|Mutations|Genotype-Phenotype Correlation|Pedigree|Muscle, Skeletal|Membrane Proteins|Mutations, Missense 60 megf10 29109235 J. Neurosci. 2017 PMC5719972 10.1523/JNEUROSCI.0862-17.2017 9 0 0 113 Animals|*Cells, Glial|Amyloid beta-Peptides|Alzheimer Disease|Drosophila Proteins|Drosophila|Peptide Fragments|Plaque, Amyloid|Neurons|Animals, Genetically Modified|Nerve Degeneration|Disease Models, Animal|Brain|Membrane Proteins|Signal Transduction|Draper protein, Drosophila 60 megf10 28642575 Nat Commun 2017 PMC5481424 10.1038/s41467-017-00037-1 37 1 0 113 *Astrocytes|*Brain Ischemia|*Phagocytes|ABCA1 protein, human|*ATP Binding Cassette Transporter 1|Microglia|Phagocytosis|Brain|*Central Nervous System|Cells, Cultured 60 METRN 29199003 Diabetes Res. Clin. Pract. 2017 10.1016/j.diabres.2017.11.031 8 1 0 47 Humans|Mice|Animals|*Diabetes Mellitus, Type 2|Diabetes Mellitus, Experimental|Adipokines|Obesity|Mice, Obese|Research Subjects 22 METRN 29097285 Diabetes Res. Clin. Pract. 2017 10.1016/j.diabres.2017.10.005 7 1 0 47 Humans|*Diabetes Mellitus, Type 2|Insulin Resistance|Blood Glucose|Glycated Hemoglobin A|Glucose Tolerance Test|Insulin|Metformin|Adiponectin|Body Mass Index 22 MFSD8 28878041 Open Biol 2017 PMC5627054 10.1098/rsob.170142 5 1 0 93 Humans|Phylogeny|*Biological Evolution|MFSD8 protein, human|Membrane Transport Proteins|Evolution, Molecular|Biological Transport|*Neurons|Bioinformatic|*Heterozygote 51 MICAL2 29180230 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.11.020 16 0 0 153 *Glucocorticoids|Corticosterone|Receptors, Glucocorticoid|DUSP1 protein, human|Dual Specificity Phosphatase 1|Cortisol|CXXC5 protein, human|Carrier Proteins|Transcriptomes|Transcription Factors|Signal Transduction|Up-Regulation|*Nervous System Physiological Phenomena|mRNA|Brain 22 MICAL2 28719045 Acta Physiol (Oxf) 2017 10.1111/apha.12920 9 4 0 153 EGFR protein, human|*Epidermal Growth Factor Receptor|*Signal Transduction|Epidermal Growth Factor|Cell Movement|Neoplasm Invasiveness|Cell Line, Tumor 22 MIDN 28724963 Sci Rep 2017 PMC5517452 10.1038/s41598-017-05456-0 4 40 0 245 Rats|Humans|Animals|midnolin|*Parkinson Disease|parkin protein|*Ubiquitin-Protein Ligases|*Nuclear Proteins|PC12 Cells|Activating Transcription Factor 4|Neurons|Cell Death|NGF protein, human|Nerve Growth Factor 23 MIDN 28611204 Clin. Cancer Res. 2017 PMC5626588 10.1158/1078-0432.CCR-16-3224 17 0 0 245 23 MIEN1 29190909 Oncotarget 2017 PMC5696175 10.18632/oncotarget.21150 2 21 0 102 Humans|Comparative Genomic Hybridization|Gastric Cancer|Oligonucleotide Array Sequence Analysis|Oncogenes|Gene Dosage|Gene Expression Profiling|DNA Copy Number Variations|Gene Expression|Chromosomes 33 MIEN1 29033401 Biosci Trends 2017 10.5582/bst.2017.01161 0 0 0 102 *cDNA Library|Two-Hybrid System Techniques|cDNA|Plasmids|Genetic Vectors|Saccharomyces cerevisiae 33 MIEN1 28859163 PLoS ONE 2017 PMC5578656 10.1371/journal.pone.0183941 1 6 0 102 Humans|*Down-Regulation|*Cell Survival|ERBB2 protein, human|Receptor, ErbB-2|Neoplasm Proteins|Cell Line, Tumor|*Carcinoma, Ductal, Breast|Proto-Oncogene Proteins c-akt|Gene Expression Regulation, Neoplastic|Intracellular Signaling Peptides and Proteins|Cell Proliferation|Signal Transduction|Breast Neoplasms 33 MIEN1 28832682 PLoS ONE 2017 PMC5568388 10.1371/journal.pone.0183179 4 4 0 102 Humans|Female|United States|Colombia|Receptor, ErbB-2|*Hispanic|Receptors, Progesterone|Biomarkers, Tumor|Genetic Predisposition to Disease|Whites|Polymorphism, Single Nucleotide|Gene Expression Regulation, Neoplastic|*Gene Expression|*Breast Cancer 33 MIEN1 28198505 Genet. Mol. Res. 2017 10.4238/gmr16019380 5 1 0 102 Humans|Phosphatidylinositol 3-Kinases|Neoplasm Proteins|Intracellular Signaling Peptides and Proteins|Cell Line, Tumor|AKT1 protein, human|Protein Kinase B|Cell Movement|Kaplan-Meier Analysis|Lymphatic Metastasis|Gene Expression|*Neoplastic Processes|MIEN1 protein, human 33 MIPEP 29220658 Mol. Cell 2017 PMC5730362 10.1016/j.molcel.2017.11.023 10 1 0 43 Coenzyme Q10 Deficiency|coenzyme Q10|*Ubiquinone|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Mitochondria|Mitochondrial Proteins|Methyltransferases|Mutation|Ataxia|Muscle Weakness 29 MIPEP 29151261 FEBS Lett. 2017 PMC5767765 10.1002/1873-3468.12914 3 11 0 43 *Sirtuin 3|*Caloric Restriction|mitochondrial intermediate peptidase|*Metalloendopeptidases|Mitochondria|Acetylation|Adipose Tissue, White 29 MIPEP 28369381 J. Antimicrob. Chemother. 2017 10.1093/jac/dkx062 1 0 0 43 lopinavir-ritonavir drug combination|*Lopinavir|*Ritonavir|*Maraviroc|*Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination|*Post-Exposure Prophylaxis|Anti-HIV Agents|*Drug Combinations|CD4 Lymphocyte Count|HIV-1|HIV Infections|HIV Protease Inhibitors|Viral Load|Medication Adherence 29 MIPEP 28327206 Genome Med 2017 PMC5361813 10.1186/s13073-017-0412-6 59 5 0 43 *Exome|High-Throughput Nucleotide Sequencing|Sequence Analysis, DNA|DNA Copy Number Variations|Computational Biology|Mutation 29 MIPEP 28041928 Cell Host Microbe 2017 10.1016/j.chom.2016.12.001 10 3 0 43 *Symbiosis|*miRNA|Medicago truncatula|Glomeromycota|Mycorrhizae|RNA, Plant|Gene Expression Regulation, Plant|Plant Roots|Plant Proteins|Genes, Plant|Gene Expression Profiling|Gene Expression 29 MIR135B 29112225 Cancer 2017 PMC5801195 10.1002/cncr.31062 8 0 0 0 *Circulating MicroRNA|*Colorectal Cancer|*Adenoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|MicroRNAs|Gene Expression Profiling|*Colonic Neoplasms|ROC Curve|Case-Control Studies 26 Mkx 29244023 Elife 2017 PMC5731821 10.7554/eLife.30474 4 24 0 126 Mice|Animals|*Hedgehog Proteins|*Osteocalcin|*Signal Transduction|Stem Cell|Tendons|*B Cells|*Musculoskeletal System|Biomechanical Phenomena 50 MLLT11 29069662 Kidney Blood Press. Res. 2017 10.1159/000484329 1 9 0 143 *Podocytes|*Adriamycin|beta Catenin|*Transcription Factors|Proteinuria|Wnt Proteins|Wnt Signaling Pathway|*Catenins|Chronic Kidney Diseases 40 MLLT11 28475127 Int J Mol Sci 2017 PMC5454900 10.3390/ijms18050987 3 31 0 143 Mice|Animals|*Proto-Oncogene Proteins c-akt|*Colorectal Cancer|*Signal Transduction|Cell Movement|Neoplasm Invasiveness|Phosphatidylinositol 3-Kinases|Cell Proliferation|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Up-Regulation|*Transcription Factors|Biomarkers, Tumor|*Colonic Neoplasms|Mice, Nude|Apoptosis|Cell Line, Tumor|*Neoplastic Processes 40 MLLT11 28423573 Oncotarget 2017 PMC5410301 10.18632/oncotarget.15574 2 5 0 143 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Transcription Factors|Cell Movement|Neoplasm Invasiveness|Neoplasm Proteins|*Disease Progression|Epithelial-Mesenchymal Transition|Signal Transduction|Proto-Oncogene Proteins|Cell Line, Tumor|*Genes, Regulator|Apoptosis|MLLT11 protein, human 40 MLLT11 28362701 Appl. Immunohistochem. Mol. Morphol. 2017 10.1097/PAI.0000000000000452 0 1 0 143 *Up-Regulation|*Leukemia, Myeloid, Acute|*Transcription Factors|MDS1 and EVI1 Complex Locus Protein|Gene Expression Regulation, Leukemic|*Genes, Regulator|*Gene Cluster|DNA-Binding Proteins|*Transcriptional Activation|Neoplasm Proteins|Disease-Free Survival|Risk Factors|Proto-Oncogene Proteins c-bcl-2 40 MPZL2 28216417 Clin. Breast Cancer 2017 PMC5482752 10.1016/j.clbc.2017.01.007 5 2 0 144 Humans|Cancer Stem Cells|Adenoid Cystic Carcinoma|SOXE Transcription Factors|AC133 Antigen|Biomarkers, Tumor|Triple-Negative Breast Cancer|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Antigens, CD|Gene Expression Profiling 22 MPZL2 28185834 Exp. Cell Res. 2017 10.1016/j.yexcr.2017.02.003 4 4 0 144 Animals|Mice|*Glioblastoma|*SCID Mice|*NOD Mice|*Cell Proliferation|*Apoptosis|*Autophagy|Brain Neoplasms|Cell Cycle|Cell Movement|Tumor Cells, Cultured|Xenograft Model Antitumor Assays|RNA, Messenger|Real-Time Polymerase Chain Reaction|RNA, Small Interfering|Signal Transduction|Blotting, Western|Endoplasmic Reticulum 22 MRGPRD 29066740 Sci Rep 2017 PMC5654773 10.1038/s41598-017-12770-0 2 9 0 47 Mice|Animals|*Alanine|*Pruritus|Nociceptors|Ganglia, Spinal|Sensory Receptor Cells|Receptors, G-Protein-Coupled|TRPV Cation Channels|Mice, Inbred C57BL|Spinal Cord 50 MRGPRD 29035722 Arch. Oral Biol. 2017 10.1016/j.archoralbio.2017.09.007 2 0 0 47 Rats|Animals|*Immunohistochemistry|*Molars|Axons|Calcitonin Gene-Related Peptide|Nerve Fibers|Dentin|Sensory Receptors 50 MRGPRD 29022879 Elife 2017 PMC5648527 10.7554/eLife.29507 4 3 0 47 Animals|*Nociceptors|Ganglia, Spinal|Nociception|Skin|Receptors, G-Protein-Coupled|*Mammals 50 MRGPRD 28240741 Sci Rep 2017 PMC5378905 10.1038/srep43493 1 2 0 47 *Formalin|*Pain|Nociceptors|Ganglia, Spinal|Sensory Receptor Cells|Pain Measurement|Capsaicin|TRPV Cation Channels 50 MSMB 29250809 Prostate 2017 10.1002/pros.23466 4 0 0 106 119 MSMB 29181843 Prostate 2017 10.1002/pros.23453 0 0 0 106 119 MSMB 29156765 Oncotarget 2017 PMC5689655 10.18632/oncotarget.20717 0 7 0 106 119 MSMB 29134700 Reprod. Domest. Anim. 2017 10.1111/rda.13111 1 1 0 106 119 MSMB 28974201 BMC Urol 2017 PMC5627473 10.1186/s12894-017-0281-8 0 0 0 106 119 MTX3 28696398 Mar Drugs 2017 PMC5532662 10.3390/md15070220 17 3 0 133 maitotoxin|*Oxocins|*Marine Toxins|*Dinoflagellates|Ciguatoxins|Ciguatera Poisoning 21 MXD1 29108267 Oncotarget 2017 PMC5668000 10.18632/oncotarget.20229 3 28 0 873 Humans|Male|CTNNB1 protein, human|*beta Catenin|*Transcription Factors|*Cell Nucleus|*Prostate Cancer|Proto-Oncogene Proteins c-myc|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Gene Expression Regulation|Transcription, Genetic|Downregulation|Prostate|Promoter Regions, Genetic|Serine Threonine Kinase 172 MXD1 28543796 Mol. Carcinog. 2017 10.1002/mc.22676 6 3 0 873 *Cisplatin|Phosphatidylinositol 3-Kinases|*Osteosarcoma|PTEN protein, human|*PTEN Phosphohydrolase|Bone Neoplasms|Apoptosis|Drug Resistance, Neoplasm|Cell Line, Tumor|Signal Transduction|Gene Expression Regulation, Neoplastic|Proto-Oncogene Proteins c-akt|*Hypoxia|Antineoplastic Agents|Cell Proliferation|siRNA|Genes, Tumor Suppressor 172 MXD1 28350847 PLoS ONE 2017 PMC5370111 10.1371/journal.pone.0174413 2 14 0 873 *Dimerization|*Splicings, Alternative|Helix-Loop-Helix Motifs|Sequence, E-Box|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Transcription Factors|DNA|Protein Binding|Proto-Oncogene Proteins c-myc|Helix-Turn-Helix Motifs|*Protein Isoforms|Leucine Zippers|Basic-Leucine Zipper Transcription Factors|Amino Acid Sequence|*Biophysics|Models, Molecular|Circular Dichroism 172 Mxi1 29234590 J Bone Oncol 2017 PMC5715438 10.1016/j.jbo.2017.05.001 5 9 0 261 *DNA Methylation|*Osteosarcoma|Protein Interaction Maps|Gene Regulatory Networks|Databases, Genetic|Gene Expression Profiling|Computational Biology|Transcription Factors|Gene Expression Regulation, Neoplastic|Signal Transduction|*Biochemical Phenomena 182 Mxi1 29222492 Sci Rep 2017 PMC5722853 10.1038/s41598-017-17371-5 3 28 0 261 *Granulocyte-Macrophage Colony-Stimulating Factor|*RNA Binding Protein|3' Untranslated Region|mRNA Decay|ELAV-Like Protein 1|mRNA|miRNA|*Protein Binding|Gene Expression Regulation|IL17A protein, human|IL-17|Type 17 Helper T Cells|IL 13|Cells, Cultured 182 Mxi1 28848114 Cell. Physiol. Biochem. 2017 10.1159/000480198 7 1 0 261 *Mesangial Cells|anti-Thy antibody|huaier|Trametes|*Nephritis|*Isoantibodies|Glomerulonephritis|Platelet-Derived Growth Factor BB|Cell Proliferation|Proto-Oncogene Proteins c-sis 182 Mxi1 28832943 Biotechnol. Bioeng. 2017 10.1002/bit.26404 19 1 0 261 *CRISPR|*Yarrowia|Genome Editing|*DNA End-Joining Repair|*Homologous Recombination|CRISPR-Cas Systems|*Genome|Synthetic Biology|Gene Expression 182 Mxi1 28575053 PLoS ONE 2017 PMC5456372 10.1371/journal.pone.0178831 1 43 0 261 Humans|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|CXCL8 protein, human|*Interleukin-8|*Umbilical Veins|*MAP Kinase Signaling System|*Human Umbilical Vein Endothelial Cells|MAPK1 protein, human|MAP Kinase 2|MXI1 protein, human|*Basic Helix-Loop-Helix Transcription Factors|*Tumor Suppressor Proteins|p38 Mitogen-Activated Protein Kinases|Phosphorylation|Signal Transduction|Cells, Cultured|Endothelium, Vascular 182 Mxi1 28541304 Nat Commun 2017 PMC5458518 10.1038/ncomms15459 30 3 0 261 *Clustered Regularly Interspaced Short Palindromic Repeats|*Saccharomyces cerevisiae|Guide RNA|*Yeast, Dried|Gene Circuits|CRISPR-Cas Systems|Synthetic Biology|*Logic|Promoter Regions, Genetic|Chromatin 182 Mxi1 28298224 Microb. Cell Fact. 2017 PMC5353793 10.1186/s12934-017-0664-2 19 5 0 261 *RNA, Guide|*Saccharomyces cerevisiae|Clustered Regularly Interspaced Short Palindromic Repeats|*Yeast, Dried|CRISPR-Cas Systems|Transcription, Genetic|Transcription Initiation Site|Synthetic Biology|Promoter Regions, Genetic 182 MXRA5 28919298 Mol. Cell. Endocrinol. 2017 10.1016/j.mce.2017.09.020 3 7 0 21 Pregnancy|Humans|Female|*Trophoblasts|*Pre-Eclampsia|Matrix Metalloproteinase 2|Matrix Metalloproteinase 9|cadherin 5|E Cadherin|Placenta|Signal Transduction|Cell Movement|CDH1 protein, human|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Viability, Cell|Apoptosis|siRNA|Downregulation|Cell Line|Antigens, CD 23 MXRA5 28720891 Sci Rep 2017 PMC5515956 10.1038/s41598-017-06033-1 15 0 0 21 Humans|*Whole Exome Sequencing|*Autism Spectrum Disorder|Saudi Arabia|Exome|Genetic Predisposition to Disease|Mutation|Disorder, Neurodevelopmental|Intellectual Disability|GLT8D1 protein, human|Glycosyltransferases 23 MYH15 28235404 BMC Syst Biol 2017 PMC5324283 10.1186/s12918-017-0396-2 12 1 0 40 Animals|*Progesterone|*Chickens|*Muscle, Skeletal|*Signal Transduction|Animal Nutritional Physiological Phenomena|Animal Feed|Muscle, Pectoralis|Transcriptomes|Mitochondria|Gene Expression Profiling 24 MYO18B 29054765 Gene 2017 10.1016/j.gene.2017.10.020 6 0 0 35 Humans|*Germ-Line Mutation|DNA Copy Number Variations|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Genetic Susceptibility|*Chinese|Oncogenes|Mutation|Pedigree|DNA Sequencing|Smoking 42 MYO18B 28913652 Mamm. Genome 2017 10.1007/s00335-017-9717-4 2 0 0 35 Mice|Animals|*C57BL Mice|*Bone|Unloading, Hindlimb|*Mice, Inbred Strains|*Bone Diseases, Metabolic|Weightbearing|Cortical Bone|Bone Formation|Disease Models, Animal|Phenotype|X-Ray Microtomography 42 MYO18B 28641578 BMC Med 2017 PMC5481993 10.1186/s12916-017-0870-0 11 11 0 35 Humans|Female|*Epigenome|Neoplasm Recurrence, Local|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Cisplatin|Drug Resistance, Neoplasm|DNA Methylation|Antineoplastic Agents|Platinum|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Biomarkers, Tumor 42 MYO18B 28641477 Pediatr. Dev. Pathol. 2017 10.1177/1093526617715528 2 0 0 35 Infant|Pregnancy|Humans|Female|*Infant Death|*Infant Mortality|Perinatal Death|*Prenatal Care|Autopsy|Fetal Death|*Fetus|*Parturition|Cause of Death|*Sequencing, Whole Genome|SRGAP2 protein, human|GTPase-Activating Proteins 42 MYO18B 28104788 Hum. Mol. Genet. 2017 10.1093/hmg/ddx025 13 0 0 35 Animals|*Sarcomeres|*Muscle, Skeletal|Myofibril|Myosins|Zebrafish|Zebrafish Proteins|Actin Cytoskeleton|Myopathies|Muscle Cell 42 myo1f 28933623 Epigenetics 2017 PMC5788422 10.1080/15592294.2017.1381807 12 0 0 128 Humans|Kabuki syndrome|*DNA Methylation|*Vestibular Diseases|*Hematologic Diseases|*Abnormalities, Multiple|*Face|KMT2D protein, human|DNA-Binding Proteins|Neoplasm Proteins|Histone Demethylases|Nuclear Proteins|Mutations|*Nucleotide Motifs|MYO1F protein, human|Myosin Type I 25 myo1f 28062691 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5278460 10.1073/pnas.1608839114 22 0 0 128 Humans|*Lymphoma, T-Cell, Peripheral|*Guanine|Proto-Oncogene Proteins c-vav|Lymphocyte Activation|*Translocation, Genetic|*Mutations, Activation|Jurkat Cells|Mutation|Signal Transduction|Base Sequence|Sequencing, RNA|VAV1 protein, human|MYO1F protein, human|Myosin Type I 25 MYO5C 28665450 Int. J. Biol. Markers 2017 10.5301/ijbm.5000285 1 0 0 604 *Squamous Cell Carcinoma of Head and Neck|*RNA, Micro|Head and Neck Neoplasms|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Gene Expression Profiling|Gene Regulatory Networks|RNA, Messenger|Down-Regulation|Cell Proliferation|Cell Line, Tumor|Signal Transduction 22 MZB1 29180208 J. Surg. Res. 2017 10.1016/j.jss.2017.07.003 1 0 0 35 *Neoadjuvant Therapy|Pancreatic Carcinoma|*Pancreatic Neoplasms|*Chemoradiotherapy|Carcinoma, Pancreatic Ductal|Pancreatectomy|Lymphocytes, Tumor-Infiltrating|Prognosis|Tumor Microenvironment|Biomarkers, Tumor|CD8-Positive T-Lymphocytes 25 MZB1 28654764 Am. J. Respir. Crit. Care Med. 2017 PMC6913086 10.1164/rccm.201611-2263OC 16 0 0 35 Humans|*Proteome|*Prevalence|*Lung|Lung Diseases, Interstitial|*Fibrosis|*B Cells|Tomography, X-Ray Computed|*Gene Expression Profiling|*Plasma|Severity of Illness Index 25 NCAM2 29191114 J. Neurogenet. 2017 10.1080/01677063.2017.1405000 1 0 0 77 Male|Animals|*Courtship|*Drosophila|Drosophila melanogaster|Drosophila Proteins|Sexual Behavior, Animal|Vocalization, Animal|Neurons|RNAi 71 NCAM2 28266018 J. Comp. Neurol. 2017 PMC5820109 10.1002/cne.24199 3 2 0 77 Animals|Mice|*mRNA|*Axons|FMR1 protein, human|Fragile X Mental Retardation Protein|Accessory Olfactory Bulb|Olfactory Marker Protein|*Smell|Neurogenesis|Sensory Neurons|*Interneurons|Synaptic Plasticity|Ribosomes 71 NCAM2 28040546 Cancer Lett. 2017 10.1016/j.canlet.2016.12.027 5 0 0 77 Humans|*Gallbladder Neoplasms|DNA Copy Number Variations|*Gallbladder|*Carcinoma, Small Cell|Carcinoma, Neuroendocrine|*Mutations|*Sequencing, Whole Genome|Sequence Analysis, DNA|Genome|Genomics|Lymphatic Metastasis 71 ncln 29169727 Biomed. Pharmacother. 2017 10.1016/j.biopha.2017.11.077 3 0 0 65 Rats|Animals|*Nigella sativa|*Diabetes Mellitus, Type 2|clinoptilolite|Diabetes Mellitus, Experimental|*Oxidative Stress|*Zeolites|Streptozotocine|*Body Weight|Malondialdehyde|Antioxidants|Catalase|Blood Glucose|*Oxidation-Reduction|Glutathione Peroxidase|Superoxide Dismutase|Lipid Peroxidation|Rats, Wistar|Glutathione 21 ncln 28922608 J Phys Chem A 2017 10.1021/acs.jpca.7b05830 1 0 0 65 Models, Molecular|Magnetic Resonance Spectroscopy 21 ncln 28294262 Dalton Trans 2017 10.1039/c7dt00618g 1 0 0 65 *Indium|*Ionic Liquids|*Water|*Chlorides|Kinetics|*Chlorine 21 ncln 28280811 Dalton Trans 2017 10.1039/c7dt00008a 2 2 0 65 *Metals, Rare Earth|*Ions|*Raman Spectroscopy|Solutions|Water 21 ncln 28274275 Genome Biol. 2017 PMC5343413 10.1186/s13059-017-1174-6 15 5 0 65 Humans|Mice|Animals|*Hirschsprung Disease|*Whole Exome Sequencing|Enteric Nervous System|Proto-Oncogene Proteins c-ret|Mutation|Genetic Predisposition to Disease|Zebrafish 21 NDFIP2 28931009 PLoS ONE 2017 PMC5606929 10.1371/journal.pone.0183774 7 49 0 108 Mice|Animals|Humans|*Aquaporin 2|HEK293 Cells|*Ubiquitination|Nedd4 Ubiquitin Protein Ligases|E3 Ligase|Endosomal Sorting Complexes Required for Transport|Carrier Proteins|Membrane Proteins|Signal Transduction|Downregulation|Epithelial Cells|siRNA|Homeostasis|NDFIP1 protein, human|NDFIP2 protein, mouse 24 NDFIP2 28798345 Sci Rep 2017 PMC5552802 10.1038/s41598-017-08284-4 4 11 0 108 Humans|Mice|Animals|Child|*Polycystic Kidney, Autosomal Recessive|*Nedd4 Ubiquitin Protein Ligases|Kidney|Phenotypes|Receptors, Cell Surface|Mutation|Biliary Tract|*Genes, Regulator|Cilia|Disease Models, Animal|RNA|PKHD1 protein, human|Pkhd1 protein, mouse|NDFIP2 protein, mouse|Membrane Proteins 24 NDFIP2 28679150 Chemosphere 2017 10.1016/j.chemosphere.2017.06.112 1 0 0 108 Animals|*Zebrafish|*Computational Biology|*Cardiovascular System|Embryo, Nonmammalian|Silicon Dioxide|*Microarray Analysis|miRNAs|Nanoparticles|mRNA|lead acetate|Organometallic Compounds|Bradycardia|Myocardial Contraction 24 NETO2 29058705 Lab. Invest. 2017 PMC5839922 10.1038/labinvest.2017.108 5 13 0 171 Humans|*Prognosis|*Transcriptome|*Melanoma|*Cell Movement|NM23 Nucleoside Diphosphate Kinases|Metastasis Suppressor Genes|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|NME1 protein, human 53 NETO2 28854365 Cell Rep 2017 PMC5600503 10.1016/j.celrep.2017.08.017 7 16 0 171 *Receptors, Kainic Acid|*Kainate|*Presynaptic Receptors|*Interneuron|Presynaptic Terminals|Parvalbumins|Membrane Proteins|LDL-Receptor Related Proteins 53 NETO2 28717010 J. Biol. Chem. 2017 PMC5602396 10.1074/jbc.M117.787903 2 4 0 171 Gluk1 kainate receptor|*Receptors, Kainic Acid|*Phosphorylation|*Serine|Synapses|Membrane Proteins|LDL-Receptor Related Proteins|Patch-Clamp Techniques 53 NETO2 28680963 eNeuro 2017 PMC5494894 10.1523/ENEURO.0048-17.2017 6 31 0 171 *Receptors, Kainic Acid|*Hippocampus|*Axons|Neurons|Synapses|Kainate|LDL-Receptor Related Proteins|Membrane Proteins|Patch-Clamp Techniques|Synaptic Transmission|Protein Subunits|Protein Transport 53 NETO2 28235897 J. Neurosci. 2017 PMC5373122 10.1523/JNEUROSCI.2978-16.2017 7 1 0 171 Mice|Animals|*Receptors, Kainic Acid|*Ganglia, Dorsal Root|*Neurite Outgrowth|*Sensory Neurons|Synapse|Membrane Proteins|Glutamate|NETO2 protein, mouse 53 Neurod2 29259353 Behav Neurol 2017 PMC5702423 10.1155/2017/9194261 1 6 0 154 Animals|Mice|*Electromagnetic Fields|*Neurogenesis|*Hippocampus|Memory|Maze Learning|Neurons|Brain|Cognition|*Experimental Model 116 Neurod2 29226333 Int. J. Cancer 2017 10.1002/ijc.31209 7 3 0 154 Humans|*Glioblastoma|*Downregulation|*Tumor Suppressor Protein p53|Phosphatidylinositol 3-Kinases|miRNA|Brain Neoplasms|*Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction|*Hypoxia|Cell Line, Tumor|Gene Expression Profiling|*Transcription Factors, General|Basic Helix-Loop-Helix Transcription Factors|Tumor Microenvironment|MIRN210 microRNA, human 116 Neurod2 28740463 Front Cell Neurosci 2017 PMC5502263 10.3389/fncel.2017.00186 3 12 0 154 Animals|Mice|*Hippocampus|Neurogenesis|Neural Stem Cells|Dentate Gyrus|Cell Differentiation|Neurons|*Adult Stem Cells|Cell Proliferation|Knockout Mouse|Immediate-Early Proteins|Tumor Suppressor Proteins|*Hematopoiesis|Aging|Fluoxetine|Neurod2 protein, mouse|Neuropeptides|Basic Helix-Loop-Helix Transcription Factors 116 Neurod2 28610919 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.06.039 8 1 0 154 Humans|*Human Embryonic Stem Cells|*Transcription Factors|Cell Differentiation|*Transgene|NEUROG1 protein, human|Basic Helix-Loop-Helix Transcription Factors|Embryonic Stem Cells|Pluripotent Stem Cells|Neurons|Nerve Tissue Proteins|NeuroD protein|Cell Culture|Lineages, Cell|Cell Line|*Hematopoiesis 116 NEUROD4 28346141 Elife 2017 PMC5429088 10.7554/eLife.24197 4 17 0 53 Animals|*Lateral Line System|*Transcriptome|Mechanoreceptors|Zebrafish|Gene Expression Regulation, Developmental 59 NEUROD4 28157484 Stem Cell Reports 2017 PMC5106529 10.1016/j.stemcr.2016.09.013 19 59 1 53 Humans|Adult|*Chromatin|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|*Neurons|Nerve Tissue Proteins|*Fibroblast|Cellular Reprogramming|Transcription Factors|Embryo, Mammalian|Cell Differentiation|Transcriptional Activation|SOX4 protein, human|SOXC Transcription Factors|NEUROG2 protein, human 59 NEUROD4 28098234 Sci Rep 2017 PMC5241638 10.1038/srep40905 10 2 0 53 Animals|*Zebrafish|*Hydrocortisone|Zebrafish Proteins|*Neurogenesis|Embryo, Nonmammalian|Larvae|Gene Expression Regulation, Developmental|Stress, Physiological|*Central Nervous System Stimulants|Microinjections|RNA, Messenger|neurod4 protein, zebrafish|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 59 NEUROD6 28914148 Laterality 2017 10.1080/1357650X.2017.1377726 4 1 0 73 Humans|Adult|*Functional Laterality|*DNA Methylation|*B-DNA|Mouth Mucosa|CpG Islands|Epigenesis, Genetic|Promoter Regions, Genetic 84 NEUROD6 28836307 Glia 2017 10.1002/glia.23193 11 1 0 73 Humans|Animals|Mice|*Spastic Paraplegia, Hereditary|*Oligodendroglia|Myelin Proteolipid Protein|Myelin|Axons|Central Nervous System|*Disease Models, Animal|*Neurons|papain-like proteinase 1|*Papain|PLP1 protein, human|Plp1 protein, mouse 84 NEUROD6 28470180 Neuropsychopharmacology 2017 PMC5549840 10.1038/npp.2017.91 5 9 0 73 Humans|*Intellectual Disability|Inhibitor of Differentiation Proteins|Inhibitor of Differentiation Protein 1|Inhibitor of Differentiation Protein 2|Helix-Loop-Helix Motifs|*Hippocampus|Basic Helix-Loop-Helix Transcription Factors|Neoplasm Proteins|Repressor Proteins|*Gene Expression|Gene Expression Regulation, Neoplastic|Cell Differentiation|Up-Regulation|*Memory|MYT1L protein, human|Nerve Tissue Proteins|Transcription Factors 84 NEUROD6 28324065 Endocrinology 2017 10.1210/en.2016-1422 12 0 0 73 Male|Animals|Rats|Humans|*Receptors, Glucocorticoid|*Mineralocorticoids|HEK293 Cells|NR3C2 protein, human|Receptors, Mineralocorticoid|NeuroD protein|*Basic Helix-Loop-Helix Transcription Factors|*Nerve Tissue Proteins|Corticosterone|Glucocorticoids|Binding Sites|Cortisol|Protein Binding|Hippocampus|Response Element|Chromatin Immunoprecipitation|3'-(1-butylphosphoryl)adenosine|*Complement Factor B 84 NEUROD6 28130357 J. Neurosci. 2017 PMC5354344 10.1523/JNEUROSCI.2414-16.2016 14 3 0 73 *Dopaminergic Neurons|*Mesencephalon|NeuroD protein|*Basic Helix-Loop-Helix Transcription Factors|*Nerve Tissue Proteins|Tegmental Area, Ventral|Tyrosine 3-Monooxygenase|Gene Expression Regulation, Developmental 84 Nfkbil1 28855605 NPJ Schizophr 2017 PMC5577284 10.1038/s41537-017-0030-8 4 1 0 46 Humans|Genome-Wide Association Study|SNPs|*Cohort Studies|Asian Continental Ancestry Group|*Schizophrenia|Genetic Predisposition to Disease|Alleles|Case-Control Studies|European Continental Ancestry Group|Ethnic Groups|Genotype|India|Genes, MHC Class II|AHI1 protein, human|Adaptor Proteins, Signal Transducing 67 Nfkbil1 28256194 Oncol. Res. 2017 10.3727/096504017X14876245096439 3 0 0 46 Humans|*Cardiotoxicity|Pilot Projects|*Doxorubicin|Antibiotics, Antineoplastic|Inflammation|Malignancies|*Cell Transformation, Neoplastic|DDX39B protein, human|DEAD-box RNA Helicases 67 NFX1 29117186 PLoS ONE 2017 PMC5695606 10.1371/journal.pone.0187514 2 21 0 98 Humans|Male|*Papillomavirus Infections|*Keratinocytes|E6 protein, Human papillomavirus type 18|Oncogene Proteins, Viral|*Human papillomavirus 16|E6 protein, Human papillomavirus type 16|Repressor Proteins|*Downregulation|Human Papilloma Virus|*Gene Expression|DNA-Binding Proteins|Signal Transduction|Foreskin|Cell Differentiation|Telomerase|mRNA|Cells, Cultured|Cell Proliferation 45 NFX1 28592444 J. Cell Biol. 2017 PMC5496613 10.1083/jcb.201610051 9 25 0 98 Humans|Mice|Animals|HeLa Cells|*Active Transport, Cell Nucleus|RNA-Binding Proteins|Serine-Arginine Splicing Factors|Cell Nucleus|Nucleocytoplasmic Transport Proteins|RNA Splicing|Cytoplasm|*RNA Transport|Nuclear Proteins|RNA, Messenger|Phosphorylation|Protein Binding|Gene Expression|Cell Differentiation 45 NFX1 28165652 Genes Chromosomes Cancer 2017 10.1002/gcc.22448 0 0 0 98 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Palmoplantar Keratoderma, Nonepidermolytic|Tylosis|Carcinoma, Squamous Cell|Genes, BRCA2|Germ-Line Mutation|Genetic Predisposition to Disease|Exome|Pedigree|Mutation, Missense|Allele|Base Sequence|Mutations|Mutation, Nonsense|Case-Control Studies|Finland 45 NHLH1 28560409 Oncol. Rep. 2017 10.3892/or.2017.5681 4 0 0 132 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Transcriptional Network|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Transcription Factors|Carcinogenesis|Biomarkers, Tumor|Upregulation|RNA, Messenger|Cell Line, Tumor|Downregulation|Genes, Homeobox 43 NINJ1 29263137 Clin. Sci. 2017 10.1042/CS20171273 1 10 0 93 Humans|Mice|Animals|Diabetes Mellitus, Experimental|NOS3 protein, human|Nitric Oxide Synthase Type III|*Protection, Cell|Neovascularization, Physiologic|Phosphorylation|Human Umbilical Vein Endothelial Cells|Proto-Oncogene Proteins c-akt|Signal Transduction|Nerve Growth Factors|Cell Adhesion Molecules, Neuronal|CASP3 protein, human|Caspase 3|Cells, Cultured|NINJ1 protein, human|Ninj1 protein, mouse 71 NINJ1 29177697 Mol. Neurobiol. 2017 10.1007/s12035-017-0810-1 0 5 0 93 71 NINJ1 29073078 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5664541 10.1073/pnas.1711814114 8 4 0 93 *Tumor Suppressor Protein p53|*Tumorigenesis|*Cell Transformation, Neoplastic|Nerve Growth Factors|Cell Adhesion Molecules, Neuronal|*Muscle Rigidity 71 NINJ1 28373430 Anticancer Res. 2017 10.21873/anticanres.11500 0 1 0 93 Humans|Male|*Neoplastic Cells, Circulating|*Cell Motility|*Prostate Cancer|*Up-Regulation|RNA, Small Interfering|Cell Adhesion|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Tumor Cells, Cultured|RNA, Messenger|Apoptosis|Cell Adhesion Molecules, Neuronal|Nerve Growth Factors|*Cell Count 71 NINJ1 28274689 Int. J. Biochem. Cell Biol. 2017 10.1016/j.biocel.2017.03.002 3 0 0 93 Animals|Rats|*Wharton Jelly|*Mesenchymal Stem Cells|*Peripheral Nerve Injuries|Mesenchymal Stem Cell Transplantation|Cell Differentiation|*Neural Guidance|*B Cells|Nerve Regeneration 71 NLRP5 29025019 Hum. Reprod. 2017 PMC6251586 10.1093/humrep/dex284 6 0 0 64 Humans|*Maternal Age|*Oocytes|In Vitro Oocyte Maturation|Meiosis|Mitochondria 65 NLRP5 28941288 Clin. Endocrinol. (Oxf) 2017 10.1111/cen.13482 0 0 0 64 Humans|*Polyendocrinopathies, Autoimmune|*Receptors, Calcium-Sensing|*Autoantibodies|*Cytokines|*Syndrome|Autoantigens|Hypoparathyroidism|Parathyroid Glands|Autoimmunity|Nuclear Proteins|Mitochondrial Proteins|NALP5 protein, human 65 NLRP5 28916717 Reproduction 2017 10.1530/REP-17-0465 5 0 0 64 Pregnancy|Humans|Female|Mice|Animals|*Genomic Imprinting|Hydatidiform Mole|Uterine Neoplasms|DNA Methylation|Oocyte|Mutations|Adaptor Proteins, Signal Transducing 65 NLRP5 28501589 Clin. Immunol. 2017 10.1016/j.clim.2017.05.009 5 0 0 64 Humans|*Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Chronic Progressive|Genotype|Disease Progression|*Modifier Gene|Phenotype|Genetic Predisposition to Disease|Age of Onset|Genetic Testing|Cohort Studies|EIF2AK1 protein, human|eIF-2 Kinase 65 NLRP5 28432035 Brain Behav. Immun. 2017 10.1016/j.bbi.2017.04.010 4 2 0 64 Humans|*Inflammasomes|*Pericytes|Escherichia coli|*Receptors, Pattern Recognition|NLR Family, Pyrin Domain-Containing 3 Protein|Pro-Caspase-1|Interleukin-1beta|Toll-Like Receptor 4|Toll-Like Receptor 2|*Brain|Carrier Proteins|Signal Transduction|Cells, Cultured|mRNA 65 NOBOX 29067606 Endocrine 2017 10.1007/s12020-017-1459-2 3 0 0 47 Humans|Female|*Homozygote|*Primary Ovarian Insufficiency|*Sisters|Exome|Pedigree|Sequencing, Whole Exome|Mutation|Amenorrhea|Brazil|NOBOX protein, human|Transcription Factors|Homeodomain Proteins 103 NOBOX 29047400 Eur. J. Med. Res. 2017 PMC5648463 10.1186/s40001-017-0285-6 3 4 0 47 Mice|Female|Animals|*Ovarian Reserve|*Diosgenin|Bone Morphogenetic Protein 15|Growth Differentiation Factor 9|Anti-Mullerian Hormone|Ovarian Follicle|Ovary|Oocytes|*Aging|*Disease Models, Animal 103 NOBOX 28969006 Oncotarget 2017 PMC5609938 10.18632/oncotarget.18833 7 0 0 47 Female|Swine|Animals|Oocyte|Ovary|Cell Differentiation|Cells, Cultured|Swine, Miniature 103 NOBOX 28923703 Theriogenology 2017 10.1016/j.theriogenology.2017.08.027 3 0 0 47 Animals|Female|*Carps|*Transcriptome Analysis|Transcriptome|Ovary|Molecular Sequence Annotation|Gene Ontology|*Sex Differentiation|Signal Pathway|*Critical Period, Psychological 103 NOBOX 28863940 Fertil. Steril. 2017 10.1016/j.fertnstert.2017.07.015 10 0 0 47 Humans|Female|*Menopause, Premature|*Primary Ovarian Insufficiency|*Chromosomal Instability|Minichromosome Maintenance Proteins|Exome|Pedigree|Genetic Predisposition to Disease|DNA Repair|Polymorphism, Single Nucleotide|Mutation|MCM8 protein, human 103 NPAS1 28499489 Biol. Psychiatry 2017 PMC6901278 10.1016/j.biopsych.2017.03.021 7 1 0 55 Animals|Mice|*Risk Factors|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Nerve Tissue Proteins|Neurogenesis|Neurons|Hippocampus|Npas1 protein, mouse 35 NPAS1 28411391 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38256 0 0 0 55 Child|Male|Humans|Chromosome Deletion|Developmental Disabilities|Intellectual Disability|Comparative Genomic Hybridization|Phenotype|Syndrome|*Chromosome Structures|NPAS1 protein, human|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 35 Npas3 28499489 Biol. Psychiatry 2017 PMC6901278 10.1016/j.biopsych.2017.03.021 7 1 0 39 Animals|Mice|*Risk Factors|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Nerve Tissue Proteins|Neurogenesis|Neurons|Hippocampus|Npas1 protein, mouse 56 Npas3 28141710 J Dev Behav Pediatr 2017 10.1097/DBP.0000000000000302 0 0 0 39 Child|Humans|Female|Animals|*Dolphins|Comparative Genomic Hybridization|*Psychosis|*Cognitive Decline|Disorganized Schizophrenia|Hallucinations|Risperidone|Anticonvulsants|Electroencephalogram 56 NPAT 29191063 Nanotoxicology 2017 10.1080/17435390.2017.1406169 7 0 0 187 Humans|*DNA Methylation|*Nanotubes, Carbon|Epigenesis, Genetic|*Workplace|Chromatography, Liquid|Tandem Mass Spectrometry|Long Interspersed Nucleotide Elements|Promoter Regions, Genetic|DNA|Occupational Exposure|Cell Line|Oncogenes 121 NPAT 28600779 Hum. Genet. 2017 PMC5502059 10.1007/s00439-017-1821-8 39 1 0 187 Humans|*Exome|Saudi Arabia|Nerve Tissue Proteins|Endoplasmic Reticulum|Golgi Apparatus|Receptors, Immunologic|Vesicular Transport Proteins|Sequencing, Whole Exome|Genes, Recessive|Homozygote|Mutations|Sequencing, Next-Generation|Sequence Analysis, DNA|Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|GRSF1 protein, human 121 NPAT 28426677 PLoS ONE 2017 PMC5398506 10.1371/journal.pone.0174031 1 0 0 187 Adult|Female|Humans|Adolescent|*Motivation|46, XX Disorders of Sex Development|Mullerian Ducts|*Health Services|Surveys and Questionnaires|*Genitalia 121 NPTX1 29156706 Oncotarget 2017 PMC5689596 10.18632/oncotarget.19347 6 8 0 493 Mice|Animals|*Ubiquitin Ligase E3|Sexual Maturation|Ribonucleoproteins|Pedigree|Mutations|RING Finger Domain|Ubiquitins 39 NPTX1 28708495 Theriogenology 2017 10.1016/j.theriogenology.2017.05.011 2 0 0 493 Sheep|Animals|Female|*Genome-Wide Association Study|*Reproduction|Breeding|*Phenotype|*Sheep, Domestic|Photoperiod|SNPs|Genotypes|Seasons|Anestrus 39 NPTX1 28334103 Cereb. Cortex 2017 10.1093/cercor/bhx046 4 1 0 493 Humans|Mice|Animals|*Glutamate|*Blood-Brain Barrier|*Neurons|Synapses|neuronal pentraxin|Nerve Tissue Proteins|Amyloid Plaques|Hippocampus|Alzheimer Disease|Synaptic Transmission|Amyloid beta-Peptides|C-Reactive Protein 39 NPTX1 28178527 Cell Rep 2017 PMC5524384 10.1016/j.celrep.2017.01.033 9 20 0 493 AMPA Receptors|Action Potentials|Neurons|Excitatory Postsynaptic Potentials|Synapses|Neuronal Plasticity|Patch-Clamp Techniques|Hippocampus|Nerve Tissue Proteins|Homeostasis|Tetrodotoxin|Cells, Cultured|Signal Transduction 39 NREP 28831851 Environ Technol 2017 10.1080/09593330.2017.1371252 0 0 0 155 Italy|Construction Materials|Waste Management|Recycling|Transportation|Global Warming|Greenhouse Gases|Impacts, Environmental|European Union|Steel 46 NREP 28689506 Epidemiol. Infect. 2017 10.1017/S0950268817001315 1 0 0 155 *Clostridium difficile|Enterocolitis, Pseudomembranous|Clostridium Infections|Cross Infection|PCR|Population Surveillance|Incidence|*Diagnostic Tests, Routine|Denmark 46 NREP 28195142 Nat Commun 2017 PMC5316879 10.1038/ncomms14517 28 1 0 155 Humans|*Genome-Wide Association Study|*Thyroid Cancer|Thyroid Cancer, Papillary|*Thyroid Gland|Carcinoma, Papillary|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Carcinoma|Genotype|Case-Control Studies 46 NUCKS1 29128114 Res. Vet. Sci. 2017 10.1016/j.rvsc.2017.10.009 1 0 0 269 Female|Animals|*Goat|*Proteome|Chromatography, Liquid|Tandem Mass Spectrometry|*Dietary Supplements|*Diets|Fish Oil|Animal Feed|*Adipose Tissue|Animal Nutritional Physiological Phenomena|*Fats, Unsaturated|Lactation|Fatty Acids|Milk|Sunflower Oil|Lipid Metabolism|Plant Oils 35 NUCKS1 28749816 Neuroreport 2017 PMC5585133 10.1097/WNR.0000000000000846 3 8 0 269 Humans|Parkinson Disease 16|*Parkinson Disease|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Asian Continental Ancestry Group|rab1 GTP-Binding Proteins 35 NUCKS1 28592245 BMC Med Genomics 2017 PMC5463402 10.1186/s12920-017-0284-z 6 7 0 269 *Lung Cancer|Gene Regulatory Networks|Gene Ontology|Protein Interaction Maps|Computational Biology|Gene Expression Profiling|*In Silico|Databases, Genetic|*Smoking|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Tobacco Smoking|Signal Transduction 35 NUCKS1 28338576 Spine 2017 10.1097/BRS.0000000000002167 4 0 0 269 Humans|Adolescent|*Scoliosis|Study, Genetic Association|*Kyphosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Alleles|Genotype|Case-Control Studies 35 NUCKS1 28247205 Apoptosis 2017 10.1007/s10495-017-1357-3 1 2 0 269 Humans|cytolethal distending toxin|*Jurkat Cells|*Aggregatibacter actinomycetemcomitans|*Bacterial Toxins|cytolethal distending toxin, Actinobacillus actinomycetemcomitans|*Apoptosis|Cell Membrane|Protein Subunits 35 OGFR 29079719 Mol. Cell Proteomics 2017 PMC5750844 10.1074/mcp.RA117.000277 8 3 0 69 Humans|HOTAIR long untranslated RNA, human|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*Liver Neoplasms|methionine-enkephalin receptor|*Proteomics|*Transcriptome|*Receptors, Opioid|*Transcriptome Analysis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Hep G2 Cells|Cell Line, Tumor|Tumorigenesis|Cell Transformation, Neoplastic|Signal Transduction|*Receptors, Growth Factor 102 olfm1 29241710 Life Sci. 2017 10.1016/j.lfs.2017.12.016 10 0 0 101 Humans|Adult|Middle Aged|Aged|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Phosphatidylinositol 3-Kinases|Neurodegenerative Diseases|Motor Neurons|MIRN92 microRNA, human|MicroRNAs|Spinal Cord|Signal Transduction|*Gene Expression|Gene Expression Profiling|Disease Progression|Biomarkers|*Biochemical Phenomena 31 olfm1 28975619 J. Neurochem. 2017 PMC5729082 10.1111/jnc.14231 0 5 0 101 Animals|*Zebrafish|*Receptors, AMPA|Extracellular Matrix Proteins|*Protein Transport|Glycoproteins|Retina|Neurons|flotillins|Membrane Proteins|Carrier Proteins|*Cell Movement|Protein Binding|Brain|Co-Immunoprecipitations 31 olfm1 28408706 Reproduction 2017 10.1530/REP-16-0651 1 1 0 101 Female|Humans|Cattle|Animals|*DNA Methylation|*Blastocysts|Embryo Culture Techniques|*Fallopian Tubes|Fertilization in Vitro|Embryonic Development|*Oviducts|Culture Media|Gene Expression Regulation, Developmental|Genomics 31 OLFML3 29138851 Oncol. Rep. 2017 PMC5783600 10.3892/or.2017.6089 4 0 0 48 *Neuropilin-1|*Tumor Initiators|*Lung Cancer|Cancer Stem Cells|POU5F1 protein, human|Octamer Transcription Factor-3|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Migration|Gene Expression Profiling|*B Cells 21 ONECUT2 28832682 PLoS ONE 2017 PMC5568388 10.1371/journal.pone.0183179 4 4 0 153 Humans|Female|United States|Colombia|Receptor, ErbB-2|*Hispanic|Receptors, Progesterone|Biomarkers, Tumor|Genetic Predisposition to Disease|Whites|Polymorphism, Single Nucleotide|Gene Expression Regulation, Neoplastic|*Gene Expression|*Breast Cancer 59 ONECUT2 28359916 Gene 2017 10.1016/j.gene.2017.03.038 21 0 0 153 Humans|*RNA, Micro|Phosphatidylinositol 3-Kinases|Biomarkers, Tumor|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Early Detection of Cancer|Lymphatic Metastasis|Transcriptome|Upregulation|Receiver Operating Characteristic|Downregulation 59 OSCP1 29227538 J. Cell. Physiol. 2017 10.1002/jcp.26349 7 1 0 406 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Liver Neoplasms, Experimental|Diethylnitrosamine|*Macrophages|Cell Proliferation|HepG2 Cells|Liver|Hepatocytes|NF-kappa B|Signal Transduction|Kupffer Cells|Apoptosis|Gene Expression Regulation, Neoplastic|Mice, Knockout|Carcinogenesis 62 OSCP1 29199269 Nat Commun 2017 PMC5712521 10.1038/s41467-017-01948-9 14 72 0 406 Humans|5-hydroxy-6-(2-(1H-imidazol-4-yl)ethylamino)cholestan-3-ol|*Liver X Receptor|*Cholestanols|5-hydroxy-6-(3-(4-aminobutylamino)propylamino)cholest-7-en-3-ol|Imidazoles|*Autophagy|Antineoplastic Agents|Cell Line, Tumor|NR4A1 protein, human|Nuclear Receptor Subfamily 4, Group A, Member 1|Cholesterol|Lysosomes|Melanoma|Leukemia, Myeloid, Acute|*Spermidine 62 OSCP1 29135101 J BUON 2017 0 0 0 406 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Prognosis|Biomarkers, Tumor|Kaplan-Meier Estimate|Immunohistochemistry|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Proportional Hazards Models|Up-Regulation 62 OSCP1 29031031 Plant J. 2017 10.1111/tpj.13744 10 0 0 406 Plant Anther|Rice|*Network, Gene|Gene Expression Regulation, Plant|Pollen|Arabidopsis|Plant Proteins|Gene Expression Profiling|Amino Acid Sequence|*Gene Expression|Phenotype|ATP-Binding Cassette Transporters|Phylogeny 62 OSCP1 28943882 Front Plant Sci 2017 PMC5596797 10.3389/fpls.2017.01580 7 14 0 406 *Oryza|*Reactive Oxygen Species|Seedlings|Catalase|Plant Roots|Antioxidants|Oxidative Stress|Hydrogen Peroxide|Superoxide Dismutase|Peroxidase|Stress, Physiological 62 OSCP1 28791396 Mol Med Rep 2017 10.3892/mmr.2017.7165 4 6 0 406 Humans|Hepatic Stellate Cells|*Wnt Signaling Pathway|*Fibrosis, Liver|Cell Proliferation|Carbon Tetrachloride|*Catenins|Transforming Growth Factor beta1|Collagen Type I|Cell Line|Blotting, Western 62 OSCP1 28666984 FASEB J. 2017 10.1096/fj.201700136RR 4 4 0 406 Humans|*Muscle, Smooth, Vascular|*Vitronectin|*Nuclear Receptor NR4A3|*Myocytes, Smooth Muscle|Neointimas|*Glycoprotein|Cell Movement|Carotid Artery Injuries|Proto-Oncogene Proteins c-sis|Becaplermin|Extracellular Matrix Proteins|Cell Proliferation|Cells, Cultured|Carotid Arteries|NR4A3 protein, human|DNA-Binding Proteins|Receptors, Steroid|Receptors, Thyroid Hormone 62 OSCP1 28664156 Front Chem 2017 PMC5471307 10.3389/fchem.2017.00034 0 5 0 406 Mice|Animals|*Endogenous Retroviruses|*Terminal Repeats, Long|*Binding Sites|Transcription Factors|Gene Expression Regulation, Developmental|Biological Evolution 62 OSCP1 28367242 J Cancer 2017 PMC5370506 10.7150/jca.17579 6 41 0 406 Humans|Male|Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Apoptosis|Cell Line, Tumor|HDAC2 protein, human|Histone Deacetylase 2|Hepatocyte Nuclear Factor 3-alpha|Autophagy|Membrane Transport Proteins|*Epigenesis, Genetic|DNA Methylation 62 OSCP1 28232113 Exp. Cell Res. 2017 10.1016/j.yexcr.2017.02.032 2 8 0 406 *Carcinoma, Hepatocellular|*Liver Cancer|*Signal Transduction|Cell Proliferation|Hep G2 Cells|Receptors, Notch|Cell Movement|Apoptosis|Downregulation|Cell Line, Tumor|siRNA 62 OSR2 28815248 Shanghai Kou Qiang Yi Xue 2017 0 0 0 68 Humans|*Ilium|*Mesenchymal Stem Cells|Bone Marrow Cells|Osteogenesis|Adipogenesis|*Mandible|Cell Differentiation|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Transcriptome|Cells, Cultured 79 OSR2 28731788 J. Dent. Res. 2017 PMC5652858 10.1177/0022034517719749 4 2 0 68 Palate|Transcription Factor|Morphogenesis|Gene Expression Regulation, Developmental|Hedgehog Proteins|Cleft Palate|Signal Transduction|Cell Proliferation 79 OSR2 28605600 J. Dent. Res. 2017 PMC5582685 10.1177/0022034517713710 3 5 0 68 Mice|Animals|BMP4 protein, human|*Bone Morphogenetic Protein 4|*Odontogenesis|activin A|*Activin|activin B|*Signal Transduction|MSX1 Transcription Factor|Tooth Germ|Transcription Factors|Homeodomain Proteins|Tooth|Gene Expression Regulation, Developmental|Mesoderm|Fibroblast Growth Factors|Molar 79 OSR2 28125717 PLoS ONE 2017 PMC5268815 10.1371/journal.pone.0170859 8 11 0 68 Humans|Female|*Endometriosis|*Transcription Factors|*Cells, Stromal|Endometrium|*Signal Transduction|DNA Methylation|CpG Islands|Epigenesis, Genetic|Gene Expression Regulation|NR5A1 protein, human|Steroidogenic Factor 1|Decitabine|*Epigenetic|Chromatin|Cells, Cultured|ROR1 protein, human|Receptor Tyrosine Kinase-like Orphan Receptors|SLC22A23 protein, human 79 OTOG 28332011 J. Assoc. Res. Otolaryngol. 2017 PMC5418161 10.1007/s10162-017-0617-9 5 0 0 16 Animals|*Zebrafish|*Otolithic Membrane|*Vestibule, Labyrinth|Larva|*Organogenesis 35 Ovol1 28892018 Int J Mol Sci 2017 PMC5618597 10.3390/ijms18091948 6 32 0 127 filaggrin|loricrin|*Antioxidants|*Artemisia|*Intermediate Filament Proteins|*Membrane Proteins|Keratinocytes|Receptors, Aryl Hydrocarbon|Dermatitis, Atopic|Cytochrome P-450 CYP1A1|Up-Regulation|Cells, Cultured|Signal Transduction|Cell Line|Plant Extracts 62 Ovol1 28703805 Cell Death Dis 2017 PMC5550867 10.1038/cddis.2017.322 13 24 0 127 Humans|filaggrin|*Dermatitis, Atopic|AHR protein, human|*Receptors, Aryl Hydrocarbon|Genome-Wide Association Study|*Intermediate Filament Proteins|Basic Helix-Loop-Helix Transcription Factors|Keratinocytes|*Eczema|Epidermis|Skin|Upregulation|Cytochrome P-450 CYP1A1|Membrane Proteins|Cell Differentiation|glyteen|Tars|Gene Expression Regulation 62 Ovol1 28578692 BMC Med 2017 PMC5458482 10.1186/s12916-017-0851-3 14 4 0 127 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Cancer, Skin|*DNA Methylation|*Prognosis|*B-DNA|*Disease Progression|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Epigenomic 62 OVOL2 28714958 Oncogene 2017 10.1038/onc.2017.178 13 0 0 96 Animals|*Transcription Factors|Drosophila melanogaster|DNA-Binding Proteins|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Oncogenesis|Signal Transduction|Cell Line, Tumor|Cell Proliferation|Cell Migration 53 oxsr1 28282258 Autophagy 2017 PMC5446055 10.1080/15548627.2017.1286431 7 11 0 594 Humans|WNK Lysine-Deficient Protein Kinase 1|*Autophagy|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|AMP-Activated Protein Kinase|Phosphorylation|Protein Binding|Transcription Factors|Minor Histocompatibility Antigens|HeLa Cells|WNK1 protein, human 38 P2RY8 29194562 Br. J. Haematol. 2017 10.1111/bjh.15056 5 0 0 46 Child|Humans|*Precursor Cells, B-Lymphoid|Neoplasm Recurrence, Local|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Ikaros Transcription Factor|Minimal Residual Disease|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Prognosis|Cohort Studies|Gene Deletion|Risk Factors|*Chronic Disease|*Relapse 52 P2RY8 29140408 Am. J. Clin. Pathol. 2017 10.1093/ajcp/aqx111 1 0 0 46 Humans|*Philadelphia Chromosome|CRLF2 protein, human|*Receptors, Cytokine|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Gene Expression Regulation, Leukemic|Janus Kinase 2|*Acute Disease|Receptors, Purinergic P2Y|*Receptors, G-Protein-Coupled|Mutation|Phenotype|JAK1 protein, human|Janus Kinase 1|P2RY8 protein, human 52 P2RY8 28866095 Cancer Lett. 2017 10.1016/j.canlet.2017.08.034 8 0 0 46 Humans|CRLF2 protein, human|Receptors, Cytokine|*Acute Lymphoblastic Leukemia|JAK2 protein, human|Janus Kinase 2|Ikaros Transcription Factor|IL2RA protein, human|*Interleukin-2 Receptor alpha Subunit|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Gene Expression Regulation, Leukemic|Mutation|Gene Rearrangement|Signal Transduction|MUC4 protein, human|Mucin-4|GPR110 protein, human 52 P2RY8 28597942 Genes Chromosomes Cancer 2017 10.1002/gcc.22477 1 0 0 46 Child|Humans|Adult|*DNA Copy Number Variations|*Polymorphism, Single Nucleotide|In Situ Hybridization, Fluorescence|Glioma|Brain Neoplasms|Mutations|Proto-Oncogene Proteins B-raf|*Gene Fusions|Genes, sis|Oncogene Proteins, Fusion|Genes, Regulator|*Clinical Laboratory Services|Cohort Studies 52 P2RY8 28408464 Blood 2017 PMC5482101 10.1182/blood-2016-12-758979 51 0 0 46 Child|Humans|Retrospective Studies|Philadelphia Chromosome|Cytokine Receptor|*Gene Fusions|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Acute Lymphoblastic Leukemia|Janus Kinase 2|Minimal Residual Disease|Signal Transduction|*Gene Targeting|Mutation|Cohort Studies 52 P2RY8 28395118 Genes Chromosomes Cancer 2017 10.1002/gcc.22464 10 0 0 46 RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|*Acute Lymphoblastic Leukemia|*Immunophenotyping|*B-Cell Leukemia|*Precursor Cells, B-Lymphoid|Oncogene Proteins, Fusion|*Leukemia, Lymphocytic, Chronic, B-Cell|In Situ Hybridization, Fluorescence|CD44 protein, human|*Hyaluronan Receptors 52 P2RY8 28371317 Pediatr Blood Cancer 2017 10.1002/pbc.26539 3 0 0 46 Child|Humans|*Acute Lymphoblastic Leukemia|CRLF2 protein, human|Receptors, Cytokine|Ikaros Transcription Factor|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Gene Expression Regulation, Leukemic|Relapse|Berlin 52 pacs2 28476937 J. Cell. Sci. 2017 PMC5482974 10.1242/jcs.199463 9 0 0 228 Animals|PACS1 protein, human|Vesicular Transport Proteins|*Adaptor Proteins, Signal Transducing|TNF-Related Apoptosis-Inducing Ligand|Protein Transport|*Homeostasis|Apoptosis|Cell Line, Tumor 38 pacs2 28115010 J Neuroinflammation 2017 PMC5260063 10.1186/s12974-016-0788-z 13 12 0 228 *Multiple Sclerosis|*Endoplasmic Reticulum Stress|*Mitochondria|Unfolded Protein Response|Transcription Factor CHOP|Mitochondrial Membranes|Apoptosis|GTPase|Neurons 38 PAGE4 28362316 Int J Mol Sci 2017 PMC5412325 10.3390/ijms18040740 10 18 0 57 Humans|Male|Adult|*Prostate|*Testis|*Prognosis|Prostate Cancer|Antigens, Neoplasm|Cell Line, Tumor|Intrinsically Disordered Proteins|Protein Conformation|*Biomarkers|Phosphorylation|PAGE4 protein, human 31 PAGE4 28289210 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5380051 10.1073/pnas.1700082114 19 12 0 57 Humans|Male|*Phosphorylation|*Intrinsically Disordered Proteins|Prostate|AR protein, human|Androgen Receptor|Prostatic Neoplasms|Clk dual-specificity kinases|Protein-Serine-Threonine Kinases|Protein Conformation|Protein-Tyrosine Kinases|Antigens, Neoplasm|Androgens|Cell Line, Tumor|Fluorescence Resonance Energy Transfer|PAGE4 protein, human 31 PALMD 29128211 J. Dairy Sci. 2017 10.3168/jds.2017-13246 6 0 0 58 Female|Cattle|Animals|*Genome-Wide Association Study|*Buffaloes|*Quantitative Trait Loci|Reproducibility of Results|*Phenotype|Milk|Breeding|Lactation|Single Nucleotide Polymorphisms|Milk Protein|Genotype|Genomics|Chromosomes 20 PALMD 28394258 J. Clin. Invest. 2017 PMC5409098 10.1172/JCI84840 27 0 0 58 Genome-Wide Association Study|*Heart|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genetic Loci|Quantitative Trait, Heritable|Genotype 20 PALMD 28148961 Sci Rep 2017 PMC5288731 10.1038/srep41608 4 9 0 58 Animals|Palmd protein, mouse|Myogenesis|Myoblasts|*Cell Differentiation|*Membrane Proteins|Myotube|RNA, Small Interfering|Cell Fusion|RNA Interference|Skeletal Muscles|Regeneration|Cell Line|Up-Regulation 20 panx3 29241211 Cell. Physiol. Biochem. 2017 10.1159/000486023 2 3 0 117 Rats|Humans|Animals|*Mesenchymal Stem Cells|*Dental Pulp|Osteogenesis|Cell Differentiation|Stem Cells|Tissue Engineering|Cells, Cultured|Cell Proliferation|Alkaline Phosphatase 67 panx3 29222846 J Tissue Eng Regen Med 2017 10.1002/term.2625 0 1 0 117 Humans|*Mesenchymal Stem Cells|*Bone Marrow|Osteogenesis|Tissue Scaffolds|Bone Marrow Cells|Cell Differentiation|Interactions, Cell|Porosity|*Polysaccharides|PANX1 protein, human|Nerve Tissue Proteins|Connexins 67 panx3 29213230 Front Cell Neurosci 2017 PMC5702652 10.3389/fncel.2017.00365 5 11 0 117 Mice|Animals|*Knockout Mouse|Connexins|Nerve Tissue Proteins|Adenosine Triphosphate|Signal Transduction|Apoptosis|Panx1 protein, mouse|Panx2 protein, mouse 67 panx3 29027020 J. Bone Miner. Metab. 2017 10.1007/s00774-017-0868-x 1 0 0 117 Mechanotransduction, Cellular|Osteocytes|Calcium Signaling|Stress, Mechanical|Cell Line|Bone Mineralization|Bone 67 panx3 28494020 PLoS ONE 2017 PMC5426780 10.1371/journal.pone.0177557 9 64 0 117 *Odontoblasts|*Cell Differentiation|Cell Proliferation|BMP2 protein, human|Bone Morphogenetic Protein 2|Signal Transduction|Odontogenesis|AMP-Activated Protein Kinase|Tooth Germs|Cell Line|siRNA|Phosphorylation|Mesenchymal Stem Cells|Junction Protein, Gap|Cell Cycle|Gene Expression Regulation|Up-Regulation 67 panx3 28390472 Reprod. Fertil. Dev. 2017 10.1071/RD16267 1 2 0 117 Male|Dogs|Rabbits|Animals|*Propidium|*Spermatozoa|Semen Preservation|*Freezing|Acrosome|Cryopreservation|Flow Cytometry|Cell Membrane|*Permeability|Immunofluorescence|Carbenoxalone 67 panx3 28295275 J. Cell. Physiol. 2017 10.1002/jcp.25906 5 0 0 117 Connexins|Nerve Tissue Proteins|Adenosine Triphosphate|Cells, Cultured|Plasma Membrane|Glycoproteins|Reactive Oxygen Species|Oxidative Stress 67 panx3 28239357 Front Physiol 2017 PMC5301028 10.3389/fphys.2017.00075 0 2 0 117 Humans|Rats|Animals|*Periodontal Ligament|*Cell Adhesion|*Molars|Tooth Eruption|*Bone Remodeling|Teeth|*Gene Expression|Collagen|*Cell Proliferation 67 PARM1 28542629 PLoS ONE 2017 PMC5436885 10.1371/journal.pone.0178041 3 9 0 49 Pregnancy|Cattle|Female|Animals|*Blastocyst|*Embryonic Development|Embryo, Mammalian|Oocytes|Fertilization in Vitro|Zygotes|Gene Expression Regulation, Developmental|mRNA|Cell Differentiation|Genes, cdc 20 PARP12 29070863 Sci Rep 2017 PMC5656619 10.1038/s41598-017-14156-8 22 10 0 93 *ADP Ribose, Poly|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|Poly(ADP-ribose) Polymerases|DNA Repair|*Golgi Complex|Cytoplasm|Cell Nucleus|Protein Transport|Signal Transduction|Proteins|*Translocation, Genetic|Poly ADP Ribosylation 20 parpbp 28894029 Mol. Cell. Biol. 2017 PMC5686578 10.1128/MCB.00117-17 2 0 0 100 Mice|Animals|*DNA Replication|*Stability, Genome|DNA Repair|Genotoxic Stress|DNA Breaks, Double-Stranded|Rad51 Recombinase|MRE11 Homologue Protein|DNA-Binding Proteins|Homologous Recombination|BRCA2 Protein|Protein Binding|Chromosome Stability|Hydroxyurea 25 pax6a 28493069 Exp Brain Res 2017 PMC5523850 10.1007/s00221-017-4977-5 1 18 0 0 Animals|*Zebrafish|*Morpholinos|*Ethanol|Hedgehog Proteins|Zebrafish Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Hindbrain|In Situ Hybridization|Retinoic Acid|Prosencephalon|Agrin|Eye|*Biomarkers|Signal Transduction|Fibroblast Growth Factors 32 pax6a 28192799 Invest. Ophthalmol. Vis. Sci. 2017 PMC5308778 10.1167/iovs.16-20235 9 27 0 0 Animals|*Retinoic Acid|*Eye|CYP1B1 protein, human|*Cytochrome P-450 CYP1B1|Zebrafish|*Vision, Ocular|Neural Crest|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|*Face|Transcription Factors 32 PCDH11Y 29229842 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5777026 10.1073/pnas.1705895114 13 1 0 45 Pregnancy|Female|Male|Humans|*Homosexuality, Male|Birth Order|Heterosexual|Siblings|Gender Identity|Family Characteristics|Mothers|Son 24 PCDH11Y 28853286 J. Proteome Res. 2017 10.1021/acs.jproteome.7b00391 6 0 0 45 Humans|Male|Female|Chromosomes, Human, Y|TYRP1 protein, human|*Membrane Glycoproteins|*Organogenesis|*Cell Differentiation|Sex Chromosomes|Transducin|TBL1Y protein, human|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 24 PCDH11Y 28241900 Reprod. Fertil. Dev. 2017 10.1071/RD16478 0 3 0 45 Humans|Male|*Fertility|Infertility, Male|Spermatozoa|Semen|Sperm Count|Sperm Motility|Spermatogenesis|*Germ Cells 24 PCDH8 29026066 Med. Sci. Monit. 2017 PMC5652140 10.12659/msm.904366 4 2 0 136 Humans|Male|*Neoplasm Grading|*Prognosis|Neoplasm Recurrence, Local|*Prostate Cancer|*Promoter Regions, Genetic|Prostatectomy|DNA Methylation|Cadherins|Disease-Free Survival|Biomarkers, Tumor|Proportional Hazards Models|PCR|Disease Progression|Risk Factors|PCDH8 protein, human 88 PCDH8 28927088 Oncol Lett 2017 PMC5588001 10.3892/ol.2017.6629 4 24 0 136 Humans|*Glycogen Synthase Kinase 3|*Proto-Oncogene Proteins c-akt|*Cell Proliferation|*Glioma|beta Catenin|Wnt Signaling Pathway|*Catenins|Phosphorylation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|PCDH8 protein, human|Cadherins 88 PCDH8 28829038 Elife 2017 PMC5601995 10.7554/eLife.26898 5 54 0 136 Animals|Neural Crest|Xenopus Proteins|Xenopus laevis|ADAM Proteins|osteoblast cadherin|Cadherins|Cell Migration|Embryo, Nonmammalian|Membrane Proteins|gamma-Secretase|Cell Nucleus|Gene Expression Regulation, Developmental|Plasma Membrane|Proteolysis|FN1 protein, human|Fibronectin|Transcription Factor|ADAM13 protein, Xenopus 88 PCDH8 28803494 Epigenomics 2017 10.2217/epi-2017-0040 6 10 0 136 Humans|*Carcinoma, Renal Cell|*Prognosis|*DNA Methylation|*B-DNA|Kidney Neoplasms|CpG Islands|Promoter Regions, Genetic|Biomarkers, Tumor 88 PCDH8 28789392 Oncol Lett 2017 PMC5529879 10.3892/ol.2017.6282 1 0 0 136 Humans|Male|*DNA Methylation|*Promoter Regions, Genetic|*Prostate Cancer|Cadherins|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Biomarkers, Tumor|Tumorigenesis 88 PCDH8 28087631 Development 2017 PMC5312037 10.1242/dev.143974 4 10 0 136 Animals|Somites|Mesoderm|Body Patterning|Receptors, Notch|Morphogenesis|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|Signal Transduction|Avian Proteins|Membrane Proteins|In Situ Hybridization|Vertebrate 88 Pcdh9 29267965 Nucleic Acids Res. 2017 PMC5829642 10.1093/nar/gkx1257 14 12 0 84 Humans|*Glioblastoma|Brain Cancer|*Cell Migration|Editing, RNA|MicroRNAs|Adenosine Deaminase|Inosine|Gene Expression Regulation, Neoplastic|Brain|RNA-Binding Proteins|Cell Proliferation|Cell Line, Tumor|Genes, Tumor Suppressor|ADAM12 protein, human|ADAM12 Protein|MIRN589 microRNA, human 63 Pcdh9 28990594 Neuropsychopharmacology 2017 PMC5854803 10.1038/npp.2017.241 7 1 0 84 *Depressive Disorder, Major|Genome-Wide Association Study|*Risk Factors|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Bipolar Disorder|Case-Control Studies|Phenotypes|Gene Expression|Brain|Genomics 63 Pcdh9 28927585 Eur. Urol. 2017 10.1016/j.eururo.2017.08.027 22 0 0 84 Humans|Male|*Transcriptome|*Prostate Cancer|*Whole Exome Sequencing|*Disease Progression|*Mutation|Genomics|Gene Expression Regulation, Neoplastic 63 Pcdh9 28791409 Mol Med Rep 2017 PMC5647006 10.3892/mmr.2017.7193 2 20 0 84 *Carcinoma, Hepatocellular|*Liver Neoplasms|DNA Methylation|CpG Islands|Promoter Regions, Genetic|Gene Silencing|Gene Expression Regulation, Neoplastic|Tumor Suppressor Proteins|Cell Proliferation|*G0 Phase|Cell Line, Tumor|mRNA|G1 Phase 63 Pcdh9 28742274 Am. J. Med. Genet. 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Genet. 2017 10.1093/hmg/ddx007 8 0 0 105 Humans|Mice|Animals|*Down Syndrome|*Cilia|*Hydrocephalus|*Brain|Trisomy|Ependyma|Neurogenesis|Disease Models, Animal|Neuroglia|Phenotypes|*Nervous System Malformations|Pcp4 protein, mouse|Nerve Tissue Proteins 109 pdia2 29222525 Sci Rep 2017 PMC5722932 10.1038/s41598-017-16947-5 3 19 0 61 Humans|Mice|Animals|*Protein Disulfide-Isomerases|*Guanine|Endothelial Cells|rhoGDI|Folding, Protein|Endoplasmic Reticulum|Signal Transduction|Sequence Alignment|Cytoskeleton|Amino Acid Sequence|NADPH Oxidase|Redox|Cell Membrane 23 pdia2 28883797 Front Physiol 2017 PMC5573733 10.3389/fphys.2017.00612 11 8 0 61 Humans|Bicuspid Aortic Valve|*Heart Valve Diseases|*Aortic Valve|*High-Throughput Nucleotide Sequencing|Aneurysm, Thoracic Aortic|Phenotype|Congenital Heart Defect|Aortic Diseases|Mutations 23 pdia2 28120266 Sci China Life Sci 2017 10.1007/s11427-016-0262-6 6 0 0 61 Humans|Male|kallikrein-related peptidase 3, human|Prostate Specific Antigen|*Prostate Cancer|Twist-Related Protein 1|Gleason Score|Prognosis|Biomarkers, Tumor|Kallikreins|Nuclear Proteins|Cadherins|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Prostatic Hyperplasia|Cell Line, Tumor|Cohort Studies|PPM1A protein, human|Protein Phosphatase 2C 23 pdia2 28070807 Cytotechnology 2017 PMC5366968 10.1007/s10616-016-0059-y 0 0 0 61 Cricetinae|Animals|Humans|glutamyl carboxylase|*Factor VII|*Drosophila|Drosophila melanogaster|*Carbon-Carbon Ligases|Factor IX|Vitamin K|Amino Acid Sequence|CHO Cells|Blood Coagulation Factors|Transfections|*Mammals|Factor II|Peptides|VKORC1 protein, human|Vitamin K Epoxide Reductases 23 PDLIM1 28339784 Biol. Reprod. 2017 10.1095/biolreprod.116.144063 9 0 0 164 Humans|Male|*Spermatogenesis|Sertoli Cells|Testis|Infertility, Male|*Autophagy|Spermatozoa|Cytoplasm|Apoptosis 43 PDZD2 29286102 Int. J. Mol. Med. 2017 PMC5819929 10.3892/ijmm.2017.3354 1 26 0 125 Rats|Animals|*Oxidative Stress|*Signal Transduction Pathway|*Collagen|Fibrosis|Heart|Myocardium|Isoprenaline|Ventricular Remodeling|Phosphorylation|MAPK1 protein, human|Mitogen-Activated Protein Kinase 2|Lipid Peroxidation|NIMA-Interacting Peptidylprolyl Isomerase|juglone|Naphthoquinones 57 PDZD2 29232926 Int J Mol Sci 2017 PMC5751285 10.3390/ijms18122683 4 42 0 125 Rats|Animals|*Muscle, Smooth, Vascular|*Myocytes, Smooth Muscle|lauric acid|Lauric Acids|Cell Migration|Epoxide Hydrolases|Platelet-Derived Growth Factor|Cell Proliferation|Atherosclerosis|Rats, Sprague-Dawley|Cells, Cultured|Hemeoxygenase 1|Enzyme Inhibitors|Adamantane|Eicosanoids 57 PDZD2 28232511 Clin. Sci. 2017 10.1042/CS20160799 10 1 0 125 Humans|Rats|Animals|SHC1 protein, human|*Src Homology 2 Domain-Containing, Transforming Protein 1|*cis-trans-Isomerase, Peptidyl-Prolyl|Caco-2 Cells|*Ischemia-Reperfusion Injury|*Mitochondria|*Apoptosis|*Intestines|Shc Signaling Adaptor Proteins|Reactive Oxygen Species|Oxidative Stress|Protein Kinase C beta|Signal Transduction|Phosphorylation|PIN1 protein, human|NIMA-Interacting Peptidylprolyl Isomerase 57 PDZD7 29142287 Sci Rep 2017 PMC5688149 10.1038/s41598-017-16014-z 6 0 0 36 Humans|Young Adult|Adult|Usher Syndrome, Type IG|Usher Syndrome, Type IC|Usher syndrome, type 2A|*Usher Syndromes|*High-Throughput Nucleotide Sequencing|Homozygote|Italy|Sequence Deletion|*Genetic Association Studies|DNA Mutational Analysis|Mutation|Pedigree|Myosins|Extracellular Matrix Proteins|Missense Mutation|Phenotype|CLRN1 protein, human|Membrane Proteins 30 PDZD7 29048736 Am. J. Med. Genet. A 2017 PMC5765442 10.1002/ajmg.a.38477 3 1 0 36 Humans|Iran|*Hearing Loss|Recessive Gene|*Chinese|Pedigree|DNA Mutational Analysis|Mutations|Homozygote|Connexins|Exome|Exons|Mutations, Frameshift|High-Throughput Nucleotide Sequencing|PDZD7 protein, human|Carrier Proteins 30 PDZD7 28439001 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5441739 10.1073/pnas.1702251114 8 2 0 36 Humans|*PDZ Domains|*Myosins|Usher Syndrome, Type IC|*Usher Syndromes|*Protein Binding|FERM Domains|Stereocilia|*Actin Cytoskeleton|radixin|Membrane Proteins|Models, Molecular|ezrin|Cytoskeletal Proteins|USH1C protein, human|Adaptor Proteins, Signal Transducing 30 PDZD7 28173822 Orphanet J Rare Dis 2017 PMC5297239 10.1186/s13023-017-0582-8 4 0 0 36 Child|Humans|*Phenotypes|Genes, Recessive|Exome|Sequencing, Whole Exome|Pedigree|*Genomics|Hearing Loss|Mutation|Microcephaly|Deafness|Genetic Linkage 30 PDZRN3 28623232 J. Biol. Chem. 2017 PMC5546041 10.1074/jbc.M117.779405 8 10 0 80 *PDZ Domains|claudin 16|Claudins|*RING Finger Domains|Tight Junctions|Loop of Henle|Protein Transport|Endocytosis|Kidney Tubules|Phosphorylation 26 PDZRN3 28143902 Sci Signal 2017 10.1126/scisignal.aag3209 3 3 0 80 Animals|Mice|*Capillary Permeability|Endothelial Cells|*Intercellular Junctions|PKC-3 protein|Protein Kinase C|E3 Ubiquitin Ligase|Ubiquitination|Cell Polarity|Signal Transduction|Actin Cytoskeleton|Phosphorylation|PDZRN3 protein, mouse 26 pgm5 29170907 J. Neurooncol. 2017 10.1007/s11060-017-2667-6 14 0 0 35 Humans|*RNA, Long Noncoding|*Glioma|Prognosis|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate 38 pgm5 28837627 PLoS ONE 2017 PMC5570346 10.1371/journal.pone.0183563 5 4 0 35 Humans|*Phosphoglucomutase|Phylogeny|Substrate Specificity|Active Site|*Mutations 38 pgm5 28797257 World J Surg Oncol 2017 PMC5553992 10.1186/s12957-017-1211-7 8 1 0 35 *RNA, Long Noncoding|*Colorectal Cancer|Tumorigenesis|Gene Expression Regulation, Neoplastic|*Disease Progression|Cell Transformation, Neoplastic|Down-Regulation|*Neoplastic Processes|Gene Expression Profiling|Cell Proliferation|Up-Regulation|Cell Line, Tumor|Cell Movement|Kaplan-Meier Estimate|*Colonic Neoplasms 38 pgm5 28255113 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2017 10.11817/j.issn.1672-7347.2017.02.003 0 0 0 35 *RNA, Long Noncoding|*Incidence|*Melanoma|Proto-Oncogene Proteins B-raf|GTP Phosphohydrolases|Skin Neoplasms|Mutation|Membrane Proteins 38 pgm5 28062797 Mol. Cell Proteomics 2017 PMC5341002 10.1074/mcp.M116.062273 11 31 0 35 Humans|*Proteomics|Adenoma|Colorectal Neoplasms|Biomarkers, Tumor|*Cell Transformation, Neoplastic|*Tumorigenesis|Chromatography, Liquid|Mass Spectrometry|Gene Expression Regulation, Neoplastic|Adenocarcinoma|Up-Regulation|Cohort Studies 38 PHLDB1 28886307 Cell. Mol. Biol. (Noisy-le-grand) 2017 10.14715/cmb/2017.63.8.2 0 0 0 51 Humans|platelet protein P47|Case-Control Studies|*Glioma|*Asian Continental Ancestry Group|*Phosphoproteins|*Blood Proteins|Genetic Predisposition to Disease|Brain Neoplasms|Polymorphism, Single Nucleotide|Allele|Gene Frequency|Genotype|Odds Ratio|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|PHLDB1 protein, human 41 PHLDB1 28134081 Clin. Exp. Rheumatol. 2017 2 0 0 51 Humans|*RNA, Micro|*Rheumatoid Arthritis|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|*Genetic Testing|Genetic Loci|Alleles|European Continental Ancestry Group|Genotype|Case-Control Studies 41 PHOX2A 29203815 Sci Rep 2017 PMC5715015 10.1038/s41598-017-17113-7 5 1 0 119 Rats|Animals|*Medulla Oblongata|Sympathetic Nervous System|Blood Pressure|Hypercapnia|*Adrenal Medulla|Rats, Wistar|Hypoxia|Hypertension|Arterial Pressure|Respiration|*Neurons|Chemoreceptor Cells|Exhalation|Brainstem|Heart Rate|Disease Models, Animal 188 PHOX2A 29044990 Environ. Toxicol. 2017 10.1002/tox.22494 0 0 0 119 Mice|Humans|Animals|*Transcriptome Analysis|Sequence Analysis, RNA|*Phototoxicity|Oligonucleotide Array Sequence Analysis|Transcriptome|*Ultraviolet Rays|SMARCC2 protein, human|Transcription Factors|Gene Regulatory Networks|Up-Regulation|Downregulation|Retina|Signal Transduction|Real-Time Polymerase Chain Reaction|Cluster Analysis|Gene Ontology|ATF7 protein, human|Activating Transcription Factors 188 PHOX2A 28767682 PLoS ONE 2017 PMC5540483 10.1371/journal.pone.0182388 8 0 0 119 Humans|Female|*HPV 16|Phylogeny|Oncogene Proteins, Viral|Cervical Cancer|Papillomavirus Infections|Papillomavirus E7 Proteins|DNA, Viral|Cervix Uteri|China|Genetic Variation|Repressor Proteins|Capsid Proteins|Polymorphism, Genetic|Base Sequence|Sequence Analysis, DNA|Mutation|Transcription Factor|Binding Site 188 PHOX2A 28240680 Anticancer Drugs 2017 10.1097/CAD.0000000000000478 5 1 0 119 Humans|*Wnt Signaling Pathway|*Neuroblastoma|*Doxorubicin|Tankyrases|*Cell Differentiation|beta Catenin|XAV939|Heterocyclic Compounds, 3-Ring|Wnt Proteins|Cell Proliferation|Cell Line, Tumor|Antineoplastic Agents|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Growth Processes 188 PHPT1 29098317 J. Mol. Med. 2017 10.1007/s00109-017-1605-6 3 2 0 62 *Hepatic Stellate Cells|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|*Fibrosis, Liver|*Signal Transduction|*Cell Movement|Transforming Growth Factor beta1|Cell Proliferation|Liver|Up-Regulation|Cell Line 42 PHPT1 28129587 Curr. Opin. Cell Biol. 2017 PMC5482761 10.1016/j.ceb.2016.12.010 16 3 0 62 Animals|*Phosphorylation|phosphohistidine|*Histidine|Prokaryotic Cells|Proteins|Signal Transduction|Spectroscopy, Mass|Posttranslational Modification|Histidine Kinase|Antibodies|Phosphatases 42 PHPT1 28105922 BMC Genomics 2017 PMC5249009 10.1186/s12864-016-3351-5 21 4 0 62 *Splicings, Alternative|*Colorectal Cancer|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|DNA Methylation|CpG Islands|*Colonic Neoplasms|*Energy Metabolism 42 PILRA 29202958 Fertil. Steril. 2017 10.1016/j.fertnstert.2017.09.023 2 0 0 23 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Transcriptome|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Alleles|Case-Control Studies|Odds Ratio|Gene Expression Regulation 38 PILRA 29181857 Neuropathol. Appl. Neurobiol. 2017 PMC6005734 10.1111/nan.12452 8 2 0 23 *Alzheimer Disease|*Whole Exome Sequencing|Genome-Wide Association Study|Genetic Predisposition to Disease|Exome|Membrane Glycoproteins|Genetic Variation|Mutation 38 PILRA 29046357 J. Biol. Chem. 2017 PMC5743085 10.1074/jbc.M117.799239 1 0 0 23 Cricetinae|Animals|Humans|*Receptors, Immunologic|glycoprotein B, Simplexvirus|Viral Envelope Proteins|Membrane Glycoproteins|Herpes Simplex Virus 1|Protein Binding|Cricetulus|Siglec|CHO Cells|*Glycopeptides|*Immunoglobulin|Glycosylation|*Thermodynamic 38 PIWIL3 29237021 Hum. Reprod. 2017 PMC5850288 10.1093/humrep/dex365 7 2 0 21 Male|Female|Humans|*Testis|*Spermatogenesis|Germ Line|Oocytes|Ovary|*Reproduction 24 PIWIL3 28869440 Cancer Biomark 2017 10.3233/CBM-170324 3 9 0 21 *Stomach Neoplasms|*Down-Regulation|*Cell Proliferation|STAT3 Transcription Factor|Gene Expression Regulation, Neoplastic|Janus Kinase 2|Cell Movement|Signal Transduction|Cell Line, Tumor|Xenograft Model Antitumor Assays 24 PIWIL3 28676534 Reproduction 2017 10.1530/REP-16-0586 5 0 0 21 Male|Humans|*Testis|Testicular Germ Cell Tumor|Neoplasms, Germ Cell and Embryonal|Testicular Neoplasms|Spermatogenesis|Argonaute Proteins|RNA, Small Interfering|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|PIWIL1 protein, human 24 PIWIL3 28094937 J. Am. Chem. Soc. 2017 10.1021/jacs.6b11751 7 0 0 21 *Enoxacin|*RNA Interference|Argonaute Proteins|piRNA|miRNAs|Cell Line, Tumor|Cell Proliferation|Germ Line|*Mass Spectrometry 24 pkd1l1 28271061 Front Cell Dev Biol 2017 PMC5318412 10.3389/fcell.2017.00005 2 6 0 17 Humans|Animals|*Zebrafish|Polycystic Kidney, Autosomal Dominant|TRPP Cation Channels|Disease, Polycystic Kidney|Mutations|TYRP1 protein, human|Membrane Glycoproteins 20 Pl15 28194945 Anal. Chem. 2017 10.1021/acs.analchem.6b04202 1 0 0 0 23 Pl15 28094156 Waste Manag 2017 10.1016/j.wasman.2016.12.032 0 0 0 0 23 PLAC1 29138842 Oncol. Rep. 2017 PMC5783604 10.3892/or.2017.6086 4 10 0 109 Humans|Male|Pregnancy|Female|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Cell Proliferation|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|RNA, Long Noncoding|Cell Movement|MicroRNAs|Cell Line, Tumor|Upregulation|Prognosis|Apoptosis|Signal Transduction|*Neoplastic Processes|Tumorigenesis|Placenta|PLAC1 protein, human 91 PLAC4 31966647 Int J Clin Exp Pathol 2017 PMC6965248 0 0 0 0 Pregnancy|Female|Humans|*Down Syndrome|*mRNA|Prenatal Diagnosis|Pregnancy Proteins|Alleles|Genotype|Polymorphism, Single Nucleotide 22 PLAC4 28648597 Genomics 2017 10.1016/j.ygeno.2017.06.004 4 0 0 0 Humans|Child|*Down Syndrome|*Trisomy|*Heart Defects, Congenital|*Genotype-Phenotype Correlation|Genotype 22 PLCL1 28790112 Clin. Cancer Res. 2017 10.1158/1078-0432.CCR-17-1269 3 0 0 51 40 PLCL1 28404686 J. Pharmacol. Exp. Ther. 2017 10.1124/jpet.116.239145 0 6 0 51 40 PLCL1 28341745 J. Biol. Chem. 2017 PMC5427276 10.1074/jbc.M117.784777 3 2 0 51 40 PLIN4 29262625 Oncotarget 2017 PMC5732791 10.18632/oncotarget.22020 4 3 0 44 Humans|*Lung Adenocarcinomas|*Genome|Lung Neoplasms|Adenocarcinoma|*Genomics|Biomarkers, Tumor|Mutation|Carcinogens|Lung|Smoke|Base Sequence 52 PLIN4 28713971 Int. J. Mol. Med. 2017 PMC5547976 10.3892/ijmm.2017.3062 10 11 0 44 Humans|Female|Mice|Animals|*RNA, Long Noncoding|*miRNAs|*mRNA|*Osteoporosis|Oligonucleotide Array Sequence Analysis|*Mandible|Ovariectomy|*Biomarkers|Signal Transduction 52 PLIN4 28501567 Biochim Biophys Acta Mol Basis Dis 2017 10.1016/j.bbadis.2017.05.011 2 0 0 44 Mice|Animals|*3T3-L1 Cells|*Adipogenesis|Adipocytes|CCAAT-Enhancer-Binding Proteins|PPAR gamma|Cell Differentiation|Transcription Factors|Jumonji Domain-Containing Histone Demethylases|Histone H3|Lipid Droplets|Triglycerides|Fibroblast|JMJD1c protein, mouse 52 PLXDC2 29263821 NPJ Genom Med 2017 PMC5685316 10.1038/npjgenmed.2016.38 11 0 0 107 Humans|*Stroke|*Brain Ischemia|*Gene Expression|Cohort Studies|*Machine Learning|Gene Expression Profiling|Probability|*Diagnostic Tests, Routine|*Biochemical Phenomena 29 PLXDC2 29261810 PLoS ONE 2017 PMC5738075 10.1371/journal.pone.0190066 1 8 0 107 29 PLXDC2 28932682 Genom Data 2017 PMC5596252 10.1016/j.gdata.2017.08.006 7 0 0 107 29 PLXDC2 28930887 J. Glaucoma 2017 10.1097/IJG.0000000000000790 2 0 0 107 29 PM20D1 29207054 Int. J. Mol. Med. 2017 PMC5752236 10.3892/ijmm.2017.3271 1 3 0 15 Humans|*Mesenchymal Stem Cells|*Bone Marrow|CpG Islands|*Leukemia, Myeloid, Acute|DNA Methylation|Epigenesis, Genetic|Promoter Regions, Genetic|MicroRNAs 27 PM20D1 29143709 Animal 2017 10.1017/S1751731117002981 4 0 0 15 Humans|Swine|Animals|*Adipose Tissue, White|Uncoupling Protein 1|Thermogenesis|Adipose Tissue, Brown|Cold|Adipose Tissue, Subcutaneous|Lipolysis|Mitochondrial Proteins|Energy Metabolism|Mitochondria|Transcription Factors|Body Temperature 27 PM20D1 28768181 Cell Metab. 2017 10.1016/j.cmet.2017.07.016 34 0 0 15 Mice|Animals|fibroblast growth factor 21|Adipose Tissue, Brown|*Fibroblast Growth Factors|Thermogenesis|Adipose Tissue, White|Uncoupling Protein 1|Energy Metabolism|Cold|Obesity|Mitochondrial Proteins|Body Weight|Mice, Knockout|Mitochondria|Ucp1 protein, mouse 27 PM20D1 28729889 Clin Epigenetics 2017 PMC5516341 10.1186/s13148-017-0371-1 14 1 0 15 DNA Methylation|HLA-DRB1 Chains|Epigenesis, Genetic|Multiple Sclerosis|Genetic Predisposition to Disease|Case-Control Studies 27 POTEE 28429804 Sci Rep 2017 PMC5399604 10.1038/srep46398 11 0 0 39 Humans|United States|*Polymorphism, Single Nucleotide|*Diaspora|African Continental Ancestry Group|Genome-Wide Association Study|European Continental Ancestry Group|Genome, Human|Genotype|Oligonucleotide Array Sequence Analysis|Genomics|Genetic Variation 20 POTEE 28284979 Ann. Allergy Asthma Immunol. 2017 10.1016/j.anai.2017.01.028 4 1 0 39 Animals|TGFB1 protein, human|*Transforming Growth Factor beta1|*Asthma|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Helminthiasis|Gene Frequency|Hypersensitivity|Genotype|Interleukin-10|Helminths 20 POTEE 28189770 J. Allergy Clin. Immunol. 2017 PMC5550370 10.1016/j.jaci.2016.12.969 3 2 0 39 Animals|*Schistosomiasis|Liver Cirrhosis|Schistosomiasis japonica|Schistosoma japonicum|Interleukin-1 Receptor-Like 1 Protein|Liver|Interleukin-33 20 pou2f3 29216297 PLoS ONE 2017 PMC5720759 10.1371/journal.pone.0189340 11 2 0 144 Mice|Animals|Olfactory Mucosa|Octamer Transcription Factors|*Gene Expression|Taste|TRPM Cation Channels|Trpm5 protein, mouse|Pou2f3 protein, mouse 50 POU3F1 28757169 Stem Cell Reports 2017 PMC5550033 10.1016/j.stemcr.2017.06.017 3 52 0 285 *Neural Tube|*Neural Crest|*Embryonic Stem Cell|DNA methyltransferase 3A|DNA (Cytosine-5-)-Methyltransferases|MicroRNAs|Cell Differentiation|DNA Methylation|Gene Expression Regulation|Downregulation|Signal Transduction 138 POU3F1 28512649 eNeuro 2017 PMC5432758 10.1523/ENEURO.0307-16.2017 4 1 0 285 Male|Humans|Adult|Middle Aged|*Schwann Cells|Sciatic Nerve|Nerve Regeneration|Peripheral Nerve Injuries|Myelin Sheath|*Skin|Coculture Techniques 138 POU3F1 28455373 Development 2017 PMC5482983 10.1242/dev.143479 9 17 0 285 Mice|Animals|*Gene Regulatory Networks|*Transcription Factors|*Chromatin Immunoprecipitation Sequencing|*Epiblast|*Genome|Mouse Embryonic Stem Cells|SOXB1 Transcription Factors|*Genomics|Gene Expression Regulation, Developmental|Cell Differentiation|Stem Cells 138 POU3F1 28154340 Biosci Trends 2017 10.5582/bst.2016.01211 2 4 0 285 Male|*Up-Regulation|yangjing|Phosphatidylinositol 3-Kinases|GC 1 compound|*Spermatogonia|GDNF protein, human|Glial Cell Line-Derived Neurotrophic Factor|*Drugs, Chinese Herbal|AKT1 protein, human|Protein Kinase B|Signal Transduction|Transcription Factor|Cell Proliferation|*Transcriptional Activation|Phosphoinositide 3 Kinase|Gene Expression Regulation|Stem Cells|Cultured Cells 138 POU3F3 29168008 Brain Struct Funct 2017 PMC5869939 10.1007/s00429-017-1563-3 1 4 0 131 Animals|Receptors, GABA-A|Hippocampus|Protein Subunits|Neurons|Glutamate Decarboxylase|Gene Expression Regulation, Developmental|Animals, Newborn 67 POU3F3 29101382 Sci Rep 2017 PMC5670244 10.1038/s41598-017-15221-y 3 2 0 131 Humans|*Stress Disorders, Post-Traumatic|*Gene Regulatory Networks|Military Personnel|*Immune System|Immunity, Innate|*Immune System Phenomena 67 POU3F3 28338200 Eur Rev Med Pharmacol Sci 2017 36 0 0 131 *RNA, Long Noncoding|*Exosomes|*Glioma|*Neovascularization, Pathologic|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|*B Cells|Cell Line, Tumor|Signal Transduction|Tumor Microenvironment|POU Domain Factors 67 POU3F4 29287890 Int. 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Otorhinolaryngol. 2017 10.1016/j.ijporl.2017.11.001 0 0 0 75 Male|Female|Siberia|Progressive hearing loss stapes fixation|*Hearing Loss, Conductive|*Hearing Loss, Sensorineural|*Genetic Diseases, X-Linked|POU Domain Factors|Deafness|Hearing Loss|Ear, Inner|Pedigree|Mutation|Russia 154 POU3F4 29137640 J Nanobiotechnology 2017 PMC5686901 10.1186/s12951-017-0317-y 1 6 0 75 Mice|Animals|*Porphyra|*Nerve Cells|*Gene Delivery Systems|POU Domain Factors|Basic Helix-Loop-Helix Transcription Factors|Cell Transdifferentiation|Nerve Tissue Proteins|Transcription Factors|Cellular Reprogramming|*Polysaccharides|Fibroblasts|Cells, Cultured|Cell Line|*Genetic Therapy 154 POU6F1 28316886 PeerJ 2017 PMC5356478 10.7717/peerj.3078 2 31 0 30 *Computational Biology|*Rheumatoid Arthritis|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Transcription Factors|Transcriptome|Signal Transduction 34 PRDM2 29228717 Oncotarget 2017 PMC5716757 10.18632/oncotarget.21713 5 3 0 177 Microsatellite Instability|DNA-Binding Proteins|Nuclear Proteins|Transcription Factors|Frameshift Mutation|Genes, Tumor Suppressor|Histone-Lysine N-Methyltransferase|Colorectal Neoplasms|Mutation|Microsatellite Repeats|*Diploidy 156 PRDM2 28892075 Nat. Biotechnol. 2017 10.1038/nbt.3966 29 0 0 177 Humans|*INDEL Mutation|Exome|*Microsatellite|Instability, Microsatellite|High-Throughput Nucleotide Sequencing|Mutation|*Tumors|Computational Biology|Oncogenes|*Diploidy|PRDM2 protein, human|Nuclear Proteins|Genes, Regulator|DNA-Binding Proteins|Histone-Lysine N-Methyltransferase|Transcription Factors|DOCK3 protein, human|Nerve Tissue Proteins 156 PRDM2 28891439 Curr Stem Cell Res Ther 2017 10.2174/1574888X11666170907113151 3 0 0 177 *Muscle Development|*Mesenchymal Stem Cells|*Cell Differentiation|*Muscle, Skeletal|Stem Cell|PRDM2 protein, human|Transcription Factors|Cells, Cultured|*Signal Transduction|DNA-Binding Proteins|Nuclear Proteins|Histone-Lysine N-Methyltransferase 156 PRDM2 28718376 Tumour Biol. 2017 10.1177/1010428317711794 3 3 0 177 *Pituitary Neoplasms|*Histones|DNA-Binding Proteins|Transcription Factors|Nuclear Proteins|Genes, Tumor Suppressor|Histone-Lysine N-Methyltransferase|DNA Methylation|*Adenoma|Promoter Regions, Genetic|Epigenesis, Genetic|Azacitidine|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|RNA, Messenger 156 PRDM2 28542097 Pharmacogenet. Genomics 2017 PMC5502740 10.1097/FPC.0000000000000284 9 0 0 177 Adult|Humans|*Ventricular Function, Left|*Genome-Wide Association Study|*Anthracyclines|*Antibiotics, Antineoplastic|Cardiotoxicity|Ventricular Dysfunction, Left|Heart Failure|Echocardiography|*Topoisomerase II Inhibitors|Risk Factors|Phenotype 156 PRDM8 29113800 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.11.021 1 1 0 41 Animals|*Neocortex|*Bipolar Disorder|Neurogenesis|*Cell Movement|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Nerve Tissue Proteins|Neural Stem Cells|Neurons|Transcription Factor|Gene Expression Regulation, Developmental|Embryo, Mammalian|Cells, Cultured|Animals, Newborn 25 PRDM8 28910750 Eur. J. Obstet. Gynecol. Reprod. Biol. 2017 10.1016/j.ejogrb.2017.08.036 1 0 0 41 Humans|Female|*Hyperplasia|*Endometrial Cancer|Endometrial Hyperplasia|DNA Methylation 25 PRDM8 28861129 Clin Epigenetics 2017 PMC5577832 10.1186/s13148-017-0389-4 4 3 0 41 Humans|*Werner Syndrome|*DNA Methylation|*B-DNA|CpG Islands|Epigenomics|Epigenesis, Genetic|Genome-Wide Association Study|Promoter Regions, Genetic|Aging, Premature|Case-Control Studies|*Blood Cells|Genetic Predisposition to Disease|Phenotypes 25 PRDM8 28556291 Environ. Mol. Mutagen. 2017 PMC6488305 10.1002/em.22095 21 1 0 41 Male|Infant, Newborn|Humans|Female|Pregnancy|phthalic acid|*DNA Methylation|*Fetal Blood|*Phthalic Acids|Maternal Exposure|Endocrine Disruptors|Prenatal Exposure Delayed Effects|Exposures, Environmental|LASP1 protein, human|Cytoskeletal Proteins|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 25 PRICKLE2 28935705 Development 2017 PMC5702074 10.1242/dev.151696 8 0 0 83 Mice|Animals|*Tectorial Membrane|*Cell Polarity|*Extracellular Matrix|Extracellular Matrix Proteins|Hearing|Hair Cells, Auditory|Epithelium|GPI-Linked Proteins|Membrane Proteins|*Orientation, Spatial|Collagen 50 PRICKLE2 28856687 J. Comp. Neurol. 2017 10.1002/cne.24311 5 0 0 83 Humans|*Depressive Disorder, Major|*Bipolar Disorder|*Chromosomes, Human, Pair 3|*Schizophrenia|Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Cohort Studies 50 PRICKLE2 28735706 Am. J. Obstet. Gynecol. 2017 PMC5671344 10.1016/j.ajog.2017.07.022 6 1 0 83 Pregnancy|Humans|Female|*Amniotic Fluid|*Transcriptome|*Meningomyelocele|Gene Expression Profiling|Cell-Free RNA|Prenatal Care|*Computational Biology 50 PRICKLE2 28544631 Andrology 2017 10.1111/andr.12362 3 0 0 83 Humans|Male|*DNA Methylation|*Spermatozoa|Infertility, Male|CpG Islands|Semen Analysis|Fecundity|*DNA|cytidylyl-3'-5'-guanosine|Dinucleoside Phosphates 50 PRICKLE2 28534241 Pediatr Cardiol 2017 10.1007/s00246-017-1636-3 3 0 0 83 Humans|Genome-Wide Association Study|*Asian Continental Ancestry Group|Genotype|Methylenetetrahydrofolate Reductase|Genetic Predisposition to Disease|*Heart Defects, Congenital|Allele|Polymorphism, Single Nucleotide|Case-Control Studies|Intron|Risk Factor|Homozygote|Heterozygote|Genetic Marker|Folate 50 PRICKLE2 28292423 Dev. Cell 2017 10.1016/j.devcel.2017.02.010 17 0 0 83 Mice|Animals|*Signal Transduction|WNT5A protein, human|Wnt-5a Protein|Wnt Proteins|Cell Polarity|Body Patterning|LIM Domain Proteins|Morphogenesis|Adaptor Proteins, Signal Transducing|Cilia|Embryo, Mammalian|Membrane Proteins 50 PRIMA1 28753106 Epigenetics 2017 PMC5739100 10.1080/15592294.2017.1356957 14 0 0 187 Humans|*Adenoma|*Colorectal Cancer|SFRP1 protein, human|*Intercellular Signaling Peptides and Proteins|*Membrane Proteins|DNA Methylation|Promoter Regions, Genetic|Biomarkers, Tumor|Carcinoma|Gene Expression Regulation, Neoplastic|Syndecan-2|Immunohistochemistry|Cell Free DNA|Cancer Screening|Specificity|PRIMA1 protein, human|Nerve Tissue Proteins|SFRP2 protein, human 67 Prrx2 29216628 Cell. Physiol. Biochem. 2017 10.1159/000485785 7 6 0 246 Humans|*Triple-Negative Breast Cancer|*Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Vimentin|Cell Line, Tumor|Cadherins|Signal Transduction|Lymphatic Metastasis|PRRX2 protein, human|Homeodomain Proteins|MIRN212 microRNA, human 84 Prrx2 28801243 Free Radic. Biol. Med. 2017 10.1016/j.freeradbiomed.2017.08.004 7 2 0 246 Animals|*Peroxiredoxin|*Hypertension, Pulmonary|Pulmonary Artery|Hypoxia|Signal Transduction|Cells, Cultured|RNA Interference|Lung|Disease Models, Animal 84 PRSS56 28611210 J. Endocrinol. 2017 10.1530/JOE-16-0636 2 3 0 17 Pregnancy|Female|Mice|Animals|HBEGF protein, human|*Heparin-binding EGF-like Growth Factor|Implantation, Embryo|*Signal Transduction|Decidua|Progesterone|Estrogens|ErbB Receptors|Egr2 protein, mouse|Early Growth Response Protein 2 26 prune2 28949121 Minerva Endocrinol. 2017 10.23736/S0391-1977.17.02737-7 1 0 0 110 Humans|*Parathyroid Neoplasms|Phosphatidylinositol 3-Kinases|Hyperparathyroidism, Primary|Hypercalcemia|Mutations|Prognosis|Phenotype 34 prune2 28300657 Gene Expr. Patterns 2017 10.1016/j.gep.2017.03.002 2 0 0 110 Animals|Mice|*Zebrafish|*Retinoic Acid|*Embryogenesis|Zebrafish Proteins|*Signal Transduction|*Transcription Factors|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Receptors, Notch|Rhombencephalon|*Genes, Regulator|Neurogenesis|Spinal Cord|Neurons|MIB1 protein, mouse|Ubiquitin-Protein Ligases|Prune2 protein, zebrafish|Neoplasm Proteins 34 PSRC1 29186428 Hum. Mol. Genet. 2017 10.1093/hmg/ddx413 0 0 0 141 Mice|Animals|Genome-Wide Association Study|*Progranulins|Leukocytes, Mononuclear|Single Nucleotide Polymorphisms|Cohort Studies|Genetic Variation|CELSR2 protein, human|Cadherins|Adaptor Proteins, Vesicular Transport|Germany|Berlin|Europe|Finland|Cdh23 protein, mouse|Celsr2 protein, mouse 90 PSRC1 28869592 Nat. Genet. 2017 10.1038/ng.3950 44 0 0 141 Humans|Carcinoma, Hepatocellular|Liver Neoplasms|Transcription Factors|Enhancer Elements, Genetic|DNA Methylation|Epigenesis, Genetic|Gene Regulatory Networks|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Neoplasm Proteins 90 PTAFR 29077727 PLoS ONE 2017 PMC5659779 10.1371/journal.pone.0187034 2 4 0 671 *Antipsychotic Agents|*Pneumonia 39 PTAFR 28993767 Front Immunol 2017 PMC5622154 10.3389/fimmu.2017.01146 2 41 0 671 39 PTAFR 28585144 J. Huazhong Univ. Sci. Technol. Med. Sci. 2017 10.1007/s11596-017-1734-8 1 0 0 671 39 PTBP2 29071887 Zhonghua Nan Ke Xue 2017 3 1 0 322 Mice|Male|Animals|*Polypyrimidine Tract-Binding Protein|*RNA|*Spermatogenesis|Spermatids|Spermatocytes|Testis|Spermatogonia|Seminiferous Tubules|mRNA|RNA-Binding Proteins|phosphoglycerate kinase, testis specific|Phosphoglycerate Kinase|Gene Expression Regulation|Gene Expression|Isoenzymes|Ptbp2 protein, mouse|Nerve Tissue Proteins 77 PTBP2 29045475 PLoS ONE 2017 PMC5646856 10.1371/journal.pone.0186654 1 3 0 322 Humans|Male|Mice|Animals|*Cryptorchidism|*Disease Models, Animal|*RNA Binding Protein|*Germ Cell|Testes|Polypyrimidine Tract-Binding Protein|Sperm|mRNA|Alternative Splicing|Nerve Tissue Proteins|Phosphoglycerate Kinase|Ptbp2 protein, mouse 77 PTBP2 28944929 Mol Med Rep 2017 PMC5865849 10.3892/mmr.2017.7572 0 13 0 322 Humans|*Glioblastoma|Brain Neoplasms|miRNA|*Oncogenes|*Oncogenesis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Prognosis|Cell Line, Tumor|Cell Movement|Signal Transduction|Bioinformatic|Gene Ontology|Cohort Studies|MIRN132 microRNA, human 77 PTBP2 28910620 Neuron 2017 PMC5637551 10.1016/j.neuron.2017.08.024 19 29 0 322 Animals|Mice|*Polyadenylation|*Microglia|*Isoforms|NOVA2 protein, human|RNA-Binding Proteins|Nerve Tissue Proteins|RNA, Messenger|3' Untranslated Regions|Neurons|Brain|Ptbp2 protein, mouse|Polypyrimidine Tract-Binding Protein|Nova2 protein, mouse|Antigens, Neoplasm 77 PTBP2 28636946 Cell Rep 2017 PMC5543815 10.1016/j.celrep.2017.05.089 11 5 0 322 Male|*Alternative Splicing|*Spermatogenesis|Polypyrimidine Tract-Binding Protein|Heterogeneous-Nuclear Ribonucleoproteins|RNA Splicing|Testis|Nerve Tissue Proteins|Sertoli Cells|Germ Cells|Exons|RNA, Messenger|Cell Differentiation|*Cell Communication|RNA|Cells, Cultured 77 PTOV1 31966450 Int J Clin Exp Pathol 2017 PMC6965838 0 0 0 127 Humans|Male|*Uterine Cervical Neoplasms|*Prognosis|*Prostatic Neoplasms|Neoplasm Proteins|Biomarkers, Tumor|Neoplasm Staging|Disease Progression|Cell Line, Tumor|RNA, Messenger|PTOV1 protein, human 38 PTOV1 28938627 Oncotarget 2017 PMC5601723 10.18632/oncotarget.19467 3 20 0 127 Humans|Male|*Docetaxel|*Prostatic Neoplasms, Castration-Resistant|Prostate|Neoplasm Proteins|Biomarkers, Tumor|Cell Line, Tumor|Disease Progression|PC3 Cells|PTOV1 protein, human 38 PTOV1 28651486 Tumour Biol. 2017 10.1177/1010428317705013 3 1 0 127 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Prognosis|Lymphatic Metastasis|*Cell Transformation, Neoplastic|Biomarkers, Tumor|*Disease Progression|*Tumorigenesis|Gene Expression Regulation, Neoplastic|Neoplasm Staging|Disease-Free Survival|Kaplan-Meier Estimate|Messenger RNA|Survival Analysis|Cell Movement|Cell Line, Tumor|Cell Proliferation 38 PTOV1 28228215 BMB Rep 2017 PMC5437967 10.5483/bmbrep.2017.50.4.024 5 21 0 127 Humans|HNRNPK protein, human|*Heterogeneous-Nuclear Ribonucleoprotein K|*Heme Oxygenase-1|HeLa Cells|miRNA|Antagomirs|RNA Interference|RNA, Small Interfering|Long Non-Coding RNA|3' Untranslated Regions|mRNA|Cell Proliferation|Cell Line, Tumor|Base Sequence|Downregulation|Binding Sites|PTOV1 protein, human|Neoplasm Proteins 38 PTPRCAP 28830214 Am. J. Chin. Med. 2017 10.1142/S0192415X1750063X 12 4 0 34 Astragalus membranaceus|Huang Qi|Drugs, Chinese Herbal|Phytotherapy|Plants, Medicinal|Saponins|Astragalus Plant|PTPRC protein, human|Leukocyte Common Antigens|Anti-Inflammatory Agents|Lymphocyte Activation|Cytokines|China 48 PTPRCAP 28827793 PLoS ONE 2017 PMC5565103 10.1371/journal.pone.0182468 0 17 0 34 *Phosphorylation|PTPRC protein, human|Leukocyte Common Antigens|*Phosphatase, Phosphoprotein|Membrane Proteins|Intracellular Signaling Peptides and Proteins|lck Kinase|*Lymphocyte|T Cells|Phosphoproteins|Lymphocyte Activation|Signal Transduction|CD4 Antigens 48 PTPRE 28968905 J. Infect. Dis. 2017 PMC5853456 10.1093/infdis/jix462 4 0 0 152 Humans|Animals|Mice|*Yellow fever virus|*Zika Virus|*Dengue Virus|*RNA|Zika Virus Infection|Yellow Fever|Dengue|Flaviviruses|Virus Replication|*T Cell Receptor 70 PTPRE 28731711 J. Proteome Res. 2017 PMC6339813 10.1021/acs.jproteome.7b00245 5 1 0 152 *Proteomics|Early Detection of Cancer|*Lung Adenocarcinoma|*Multiple Pulmonary Nodules|Lung Cancer|Adenocarcinomas|Solitary Pulmonary Nodule|Biomarkers, Tumor|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|CEACAM6 protein, human|Cell Adhesion Molecules|Antigens, CD|GPI-Linked Proteins|Chromatography, Liquid 70 PTPRE 28235043 PLoS Pathog. 2017 PMC5342304 10.1371/journal.ppat.1006232 3 24 0 152 Humans|*Hepacivirus|*src Kinases|Leukocytes, Mononuclear|*Hepatitis C|*Lymphocyte Activation|Receptors, Antigen, T-Cell|RNA, Viral|PTPRE protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 4|Signal Transduction|*Phosphoric Monoester Hydrolases|Liver|Hepatocyte|T-Lymphocytes 70 PTPRM 28771244 Genet. Med. 2017 PMC5846809 10.1038/gim.2017.83 16 4 0 98 Child|Humans|*Cerebral Palsy|*Hemiplegia|*DNA Copy Number Variations|Genetic Predisposition to Disease|Genotype|Chromosomes, Human|Case-Control Studies 52 PURG 29221753 Gene 2017 PMC5770235 10.1016/j.gene.2017.12.004 3 9 0 44 Animals|Humans|Mice|*Cell Cycle Proteins|JC polyomavirus|Cyclic AMP Response Element-Binding Protein|Transcription, Genetic|Cells, Glial|RNA Sequence|Leukoencephalopathy, Progressive Multifocal|Promoter Regions, Genetic|*Nucleoproteins|Cell Cycle|*Mammals|Myelodysplastic Syndrome|Cell Division 36 PURG 29113434 J. Am. Chem. Soc. 2017 PMC5724027 10.1021/jacs.7b09384 2 4 0 44 *Catalytic Domain|*Hydrolysis|diisopropyl-fluorophosphatase|Phosphoric Triester Hydrolases|Paraoxonase 1|*Organophosphates|gluconolactonase|Carboxylic Ester Hydrolases|Substrate Specificity|Diisopropylfluorophosphate|phosphorylphosphatase|Phosphoric Monoester Hydrolases|Mutations 36 PURG 28493633 Angew. Chem. Int. Ed. Engl. 2017 10.1002/anie.201701488 0 0 0 44 *Dimerization|*Solvents|Ruthenium|Catalysis|Coordination Complexes|Water|Thermodynamics|Oxidation-Reduction 36 PURG 28489001 Elife 2017 PMC5425252 10.7554/eLife.24901 0 4 0 44 Humans|*Metacognition|*Noradrenaline|Double-Blind Method|Psychomotor Performance|Decision Making|Propranolol|Arousal|Dopamine|Amisulpride 36 PURG 28250941 IUCrJ 2017 PMC5331465 10.1107/S2052252516018017 7 1 0 44 Directed Molecular Evolution|Protein Engineering 36 PYHIN1 28077445 Mol. Cell Proteomics 2017 PMC5393386 10.1074/mcp.M116.064741 8 1 0 57 Humans|*Herpesvirus 1, Human|*Herpes Simplex|Immediate-Early Proteins|Viral Proteins|Virus Replication|Nuclear Proteins|Gene Expression Regulation, Viral|Ubiquitin-Protein Ligases|*Virus Inductions|Transcription Factors|Phosphoproteins|Host-Pathogen Interactions|DNA, Viral|TYRP1 protein, human|*Membrane Glycoproteins|Proteasome|*Antiviral Agents|Ubiquitination 20 RAD54B 28803330 Chromosome Res. 2017 PMC5662671 10.1007/s10577-017-9563-y 1 2 0 120 Meiosis|*Tetrahymena|*Homologous Recombination|DNA Breaks, Double-Stranded|RAD51 Protein|Crossing Over, Genetic|Chromatids|Chromosome Pairing|DNA Repair|RAD54B protein, human|DNA Helicases|Saccharomyces cerevisiae Proteins|Cell Cycle Proteins|Chromosome Segregation|DNA-Binding Proteins|Saccharomyces cerevisiae|Nuclear Proteins|*Cell Nucleus Division 67 RAD54B 28622436 FEBS J. 2017 10.1111/febs.14137 0 1 0 120 Humans|*Arms|*Gene Targeting|RAD54B protein, human|DNA Helicases|Nuclear Proteins|DNA Repair|DNA-Binding Proteins|Exon|Genetic Vectors|Homologous Recombination|Gene Expression|Phenotype|*Rhabdomyosarcoma, Alveolar|Cell Line 67 RAD54B 28541631 J Gynecol Oncol 2017 PMC5447142 10.3802/jgo.2017.28.e39 8 0 0 120 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|Genes, BRCA2|Genes, BRCA1|*Sequencing, Next-Generation|*Homologous Recombination|Germ-Line Mutation|*Chinese|Mutation|*Germ Line 67 RAD54B 28295846 Genes Chromosomes Cancer 2017 10.1002/gcc.22458 0 0 0 120 RAD54B protein, human|*DNA Helicases|*Nuclear Proteins|*Genome Instability|*Oncogene|DNA Repair|DNA Damage|Cell Cycle Checkpoints|*Cancer|*Genes, Tumor Suppressor 67 RAD54B 28232668 Nat Commun 2017 PMC5333091 10.1038/ncomms14364 46 2 0 120 Humans|Orofacial Cleft 7|*Cleft Lip|Cleft Palate|*Genome-Wide Association Study|*Genetic Heterogeneity|SNPs|Chinese|Genetic Loci|Genetic Predisposition to Disease|Alleles|Genotype|Case-Control Studies|RAD54B protein, human|DNA Helicases|Nuclear Proteins|Ethnicity|Ectodermal Dysplasia|Syndactyly 67 RAP1GDS1 29145128 Stem Cell Res 2017 10.1016/j.scr.2017.11.002 1 1 0 152 Mice|Animals|Endothelial Cells|*Cell Differentiation|Embryoid Body|*Microgravity Simulation|Mouse Embryonic Stem Cells|RAP1GDS1 protein, human|*Morphogenesis|Neovascularization, Physiologic|cdc42 GTP-Binding Protein|Signal Transduction|Microgravity|Cell Line|*Guanine Nucleotide Exchange Factor 48 RAP1GDS1 28806394 Oncogene 2017 PMC5730474 10.1038/onc.2017.280 2 67 0 152 *Cell Cycle|RAP1GDS1 protein, human|Guanine Nucleotide Exchange Factor|*Cell Division|*Gene Expression|Small GTPases|MYBL2 protein, human|Cell Cycle Proteins|Cell Line, Tumor|*Cell Nucleolus|Lung Neoplasms|Protein Binding|RNAi|Cell Proliferation|Trans-Activators|Cell Movement|Nuclear Proteins 48 RAP1GDS1 28630045 J. Biol. Chem. 2017 PMC5555202 10.1074/jbc.M117.792556 6 1 0 152 Animals|*Guanine Nucleotide Exchange Factor|*Armadillos|*Protein Binding|RHOA protein, human|rhoA GTP-Binding Protein|RASGRF1 protein, human|*ras-GRF1|Small GTPases|Guanosine Triphosphate|Isoforms|Amino Acid Sequence|*Protein Domains 48 RAP1GDS1 28119923 Biomed Res Int 2017 PMC5227119 10.1155/2016/2789245 1 11 0 152 Humans|*Mesenchymal Stem Cells|*Proteome|Bone Marrow Cells|quinone|*Benzoquinones|Hematopoietic Stem Cells|Cell Differentiation|Bone Marrow|Cells, Cultured|Cell Proliferation|hydroquinone|Hydroquinones|RAP1GDS1 protein, human|Guanine Nucleotide Exchange Factors 48 rap2a 29208693 Physiol Rep 2017 PMC5727288 10.14814/phy2.13541 6 21 0 251 Humans|*Junctional Adhesion Molecule A|Caco-2 Cells|*Ethanol|F11R protein, human|*Cell Adhesion Molecules|*Receptors, Cell Surface|Tight Junction|*Epithelial Cell|Occludin|*Intestines|Intestinal Epithelium|Claudins|Myosin-Light-Chain Kinase|Permeability|Phosphorylation|Myosin Light Chains 128 rap2a 29089386 J. 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Chem. 2017 PMC5743069 10.1074/jbc.M117.809541 4 1 0 251 *Guanine Nucleotide Exchange Factor|*Small GTPases|*Neurons|RASGRF1 protein, human|*ras-GRF1|rap GTP-Binding Proteins|rap1 GTP-Binding Proteins|*Adaptor Proteins, Signal Transducing|Nerve Tissue Proteins|Axons|Signal Transduction|Cell Polarity 128 rap2a 31966838 Int J Clin Exp Pathol 2017 PMC6965967 1 0 0 251 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Immunohistochemistry|Prognosis|Biomarkers, Tumor|Kaplan-Meier Estimate|Gene Expression Regulation, Neoplastic|Upregulation|Cell Migration|Proportional Hazards Models|Western Blot|Real-Time PCR, Quantitative|RAP2A protein, human|rap GTP-Binding Proteins 128 rap2a 28747626 Sci Rep 2017 PMC5529368 10.1038/s41598-017-06162-7 4 16 0 251 Humans|*Carcinoma, Renal Cell|*Proto-Oncogene Proteins c-akt|*Prognosis|Kidney Neoplasms|Cell Movement|*Up-Regulation|rap GTP-Binding Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Downregulation|Signal Transduction|Matrix Metalloproteinase 2|*Transcriptional Activation|Phosphorylation|RNA, Small Interfering|RAP2A protein, human 128 RAPGEF6 28970849 J Breast Cancer 2017 PMC5620438 10.4048/jbc.2017.20.3.240 3 3 0 96 Humans|*Gene Regulatory Networks|*Triple Negative Breast Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Databases, Genetic|*Gene Expression|Signal Transduction|*Biochemical Phenomena 25 RAPGEF6 28917843 Biochem. 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Commun. 2017 10.1016/j.bbrc.2017.09.062 0 3 0 96 Animals|Mice|*Guanine Nucleotide Exchange Factor|*Small GTPases|*Up-Regulation|*Ependymoglial Cells|*Adherens Junctions|RAP1A protein, human|rap1 GTP-Binding Proteins|RASGRF1 protein, human|*ras-GRF1|*Protein Processing, Post-Translational|Signal Transduction|*Transcriptional Activation|CDH1 protein, human|N-Cadherin|Extracellular Signal-Regulated MAP Kinases|Mice, Knockout|Neurons|Cell Movement 25 RAPGEF6 28537769 Genet Test Mol Biomarkers 2017 10.1089/gtmb.2016.0402 0 2 0 96 Humans|Aged|Genome-Wide Association Study|*Chinese|*Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Gene Frequency|Genotype|European Continental Ancestry Group|Metabolic Syndrome|Guanine Nucleotide Exchange Factor|RAPGEF6 protein, human|KSR2 protein, human|Protein-Serine-Threonine Kinases 25 RASGEF1B 28947785 Sci Rep 2017 PMC5612941 10.1038/s41598-017-12550-w 6 3 0 25 *Toll-Like Receptor 4|*Lipopolysaccharides|*RNA, Circular|*Transcriptome|*Transcriptome Analysis|Signal Transduction|NF-kappa B|Macrophages|Gene Expression Regulation 28 RASGEF1B 28371330 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38176 1 0 0 25 Male|Humans|Adolescent|DNA Copy Number Variations|*Cerebral Palsy|Chromosome 4q- Syndrome|*Chromosome Deletion|*Chromosome Disorders|Intellectual Disability|Abnormalities, Multiple|*Chromosomes, Human, Pair 4|Phenotype|Speech Delay|Muscular Hypotonia|Syndrome 28 RBM24 29104163 Int. J. Biochem. Cell Biol. 2017 10.1016/j.biocel.2017.11.002 1 1 0 140 *RNA Binding Protein|mRNA Stability|Immunoprecipitation|Alternative Splicing|RNA, Messenger|3' Untranslated Regions|Gene Knockdown Techniques|Myocytes, Cardiac|Cell Differentiation|Isoforms 41 RBM24 28869592 Nat. Genet. 2017 10.1038/ng.3950 44 0 0 140 Humans|Carcinoma, Hepatocellular|Liver Neoplasms|Transcription Factors|Enhancer Elements, Genetic|DNA Methylation|Epigenesis, Genetic|Gene Regulatory Networks|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Neoplasm Proteins 41 RBM24 28850611 PLoS ONE 2017 PMC5574583 10.1371/journal.pone.0184093 6 7 0 140 Mice|Animals|*Ventricular Remodeling|*RNA Binding Protein|RNA Splicing|Heart|Myocardium|Alternative Splicing|RNA Stability|Muscle, Skeletal|Cell Differentiation|Protein Isoforms|Hematopoiesis|Fibrosis 41 RBM24 28753211 Sci Rep 2017 PMC5492276 10.1038/srep46854 0 1 0 140 *Sarcomeres|*Myocytes, Cardiac|*Protein Stability|RNA-Binding Proteins|Cell Differentiation 41 RBM24 28592461 RNA 2017 PMC5558909 10.1261/rna.059428.116 7 1 0 140 *Ribonucleoprotein, U1 Small Nuclear|*RNA Splice Sites|Dysautonomia, Familial|RNA Splicing|Exons|Introns|Alternative Splicing|*Mutation|*Spliceosomes|Carrier Proteins|Transcriptional Elongation Factors|Cell Line 41 RBM24 28322254 Sci Rep 2017 PMC5359592 10.1038/srep44870 5 23 0 140 *Sarcomeres|*Myocytes, Cardiac|Cell Differentiation|RNA-Binding Proteins|Heart Contractility|Co-Immunoprecipitation|*Protein Stability|Signal Transduction|Phosphorylation|Organogenesis 41 RBMS3 29187421 G3 (Bethesda) 2017 PMC5919749 10.1534/g3.117.300382 0 0 0 104 Animals|*Chickens|Genome-Wide Association Study|Egg Shell|Breeding|Haplotype|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Genotype|Phenotype|Pigmentation|*Color 41 RBMS3 29134320 Acta Neuropathol. 2017 PMC5773659 10.1007/s00401-017-1785-8 13 11 0 104 Humans|*Amyotrophic Lateral Sclerosis|*Neurodegenerative Diseases|*Artificial Intelligence|RBM6 protein, human|*RNA-Binding Proteins|Motor Neurons|Mutations 41 RBMS3 28553957 Nat. Genet. 2017 PMC6685441 10.1038/ng.3875 18 0 0 104 Humans|*Exfoliation Syndrome|Genetic Predisposition to Disease|Amino Acid Oxidoreductases|Polymorphism, Single Nucleotide|*Study, Genetic Association|Haplotypes|Allele|Gene Frequency|Asian Continental Ancestry Group|Glaucoma|Case-Control Studies|Risk Factor|LOXL1 protein, human 41 RBMS3 28409548 Oncol. Res. 2017 10.3727/096504017X14871200709504 5 2 0 104 Humans|Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Neoplastic Processes|Cell Line, Tumor|Cell Transformation, Neoplastic|Downregulation|RBMS3 protein, human|Trans-Activators|RNA-Binding Proteins 41 RBMS3 28377053 Artif Intell Med 2017 10.1016/j.artmed.2017.03.010 7 0 0 104 Humans|*Transcription Factors|*Lung Adenocarcinoma|Adenocarcinoma|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Computational Biology|Gene Expression Profiling|Cell Transformation, Neoplastic|Databases, Genetic|Cell Proliferation 41 RC3H1 29246441 Immunity 2017 10.1016/j.immuni.2017.11.008 22 8 0 430 *T-Lymphocytes, Regulatory|*Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|*Lymphocyte Activation|Germinal Center|Cell Differentiation|IL2RA protein, human|Interleukin-2 Receptor alpha Subunit|PTEN protein, human|PTEN Phosphohydrolase|Th17 Cells|E3 Ubiquitin Ligase|Autoimmunity|*Hematopoiesis|Colitis 71 RC3H1 29244194 Eur. J. Immunol. 2017 10.1002/eji.201747109 7 7 0 430 Mice|Animals|*mRNA|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|DNA-Binding Proteins|Th17 Cells|RNA Stability|Interleukin 6|RNA Binding Protein|Interleukin-17|3' Untranslated Regions|Encephalomyelitis, Autoimmune, Experimental|Autoimmunity|Arid5a protein, mouse|Transcription Factors 71 RC3H1 29127149 J. Immunol. 2017 10.4049/jimmunol.1701211 11 6 0 430 Mice|Animals|*Cell Differentiation|*Endoribonucleases|mRNA|RNA-Binding Proteins|Th17 Cells|Ribonucleases|Ubiquitin-Protein Ligases|Lymphocyte Activation|Inflammation|*Fibrosis 71 RC3H1 29114069 J. Cell Biol. 2017 PMC5716268 10.1083/jcb.201701064 12 39 0 430 *Hexokinase|*mRNA|*Glycolysis|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|RNA-Binding Proteins|Cell Line, Tumor|Cell Proliferation|Adaptor Proteins, Signal Transducing|Gene Expression Regulation, Neoplastic|*Citric Acid Cycle 71 RC3H1 28747346 J. Immunol. 2017 PMC5570526 10.4049/jimmunol.1602069 0 4 0 430 Mice|Animals|Mycobacterium tuberculosis|Tuberculosis|*Myeloid Cells|CD4-Positive T-Lymphocytes|Lung|Lymphocyte Activation|Mice, Inbred C57BL 71 RC3H1 28369485 Int. Immunol. 2017 PMC5890888 10.1093/intimm/dxx015 4 12 0 430 Mice|Animals|cysteinylcysteine|*mRNA Stability|ZFP36 protein, human|Tristetraprolin|RNA-Binding Proteins|*Dipeptides|RNA, Messenger|Ribonucleases|Zinc Fingers|Transcription Factors|Endoribonucleases|Ubiquitin-Protein Ligases|RNA|Mice, Knockout|Inflammation|Zinc 71 RC3H1 28242651 J. Immunol. 2017 PMC5357783 10.4049/jimmunol.1403088 17 5 0 430 *Autoimmunity|*Metformin|Germinal Centers|Helper Cell|B Cells|MTOR protein, human|TOR Serine-Threonine Kinases|Lupus Erythematosus, Systemic|Plasma Cells|Lymphocyte Activation|Signal Transduction|Autoantibodies|STAT3 Transcription Factor|Cell Differentiation 71 RC3H1 28188245 J. Immunol. 2017 10.4049/jimmunol.1601732 3 0 0 430 Mice|Animals|*Natural Killer T-Cells|Lymphocyte Activation|Cell Differentiation|Cell Lineage|Cytokines|Transcription Factors 71 RC3H1 28165457 Nat Commun 2017 PMC5303829 10.1038/ncomms14307 21 64 0 430 Humans|Animals|*mRNA|*Drosophila|Drosophila melanogaster|mRNA Degradation|RNA-Binding Proteins|Drosophila Proteins|Protein Binding|Ribonucleases|Binding Sites|Conserved Sequence|Transcription Factors|Crystallography, X-Ray|Ubiquitin-Protein Ligases|Models, Molecular|CCR4 protein, human|Receptors, CCR4|CCR4 protein, Drosophila 71 REG1A 29286311 Proteomes 2017 PMC5874760 10.3390/proteomes6010001 8 1 0 2130 Humans|Male|*Proteomics|*Receptor, Retinoid X|Chromatography, Liquid|*Liver X Receptor|*Down-Regulation|*Acute-Phase Reaction|Tandem Mass Spectrometry|*Prostate Cancer|Prostatic Hyperplasia|*Signal Transduction|Biomarkers, Tumor|Gene Expression Profiling|Renal Cancer|Bioinformatics|REG1A protein, human|Lithostathine|ACTG2 protein, human|Actins 307 REG1B 28877242 PLoS ONE 2017 PMC5587329 10.1371/journal.pone.0183908 9 2 0 24 Humans|*Diabetes Mellitus, Type 1|*Proteomics|Islets of Langerhans|Pancreas|Laser Capture Microdissection|Insulin|Pancreatic beta Cells|Mass Spectrometry|Autoantibodies|Inflammation|*Laser 36 RELT 28736008 Transplant. Proc. 2017 10.1016/j.transproceed.2017.01.083 0 0 0 87 Humans|*Reoperation|Liver Failure|Liver Transplantation|Graft Survival|Follow-Up Studies|*Liver|Retrospective Studies|Risk Factors|*Elective Surgical Procedures|Time Factors|Multivariate Analysis 46 RELT 28688764 Biochem. Biophys. Res. Commun. 2017 PMC5617334 10.1016/j.bbrc.2017.07.022 11 40 0 87 Humans|TNFRSF1A protein, human|*Receptors, Tumor Necrosis Factor, Type I|*Apoptosis|Receptors, Tumor Necrosis Factor|CASP8 protein, human|Caspase-8|TRAF2|Signal Transduction|MAPK, p38|NF-kappa B|Apoptosis Regulatory Proteins|Tumor Necrosis Factor-alpha|*Tissues, Lymphoid 46 RELT 28508139 J Mol Model 2017 10.1007/s00894-017-3361-5 0 0 0 87 *Toxin-Antitoxin Systems|*Xenorhabdus|Escherichia coli|Antitoxins|Operon|Escherichia coli Proteins|Bacterial Toxins|Bacterial Proteins|RELT|*Receptors, Tumor Necrosis Factor|Promoter Regions, Genetic|*In Silico 46 RETNLB 28973871 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5651776 10.1073/pnas.1711395114 18 0 0 201 Humans|Mice|Animals|RETN protein, human|*Resistin|*Intestinal Epithelium|*Colon|*Microbiota|Hormones, Ectopic|Intestine|*Proteins|Pancreatitis-Associated Proteins|Gram Negative Bacteria|Mutualism|*Anti-Bacterial Agents 152 RETNLB 28882697 Hum. Pathol. 2017 10.1016/j.humpath.2017.08.027 2 0 0 201 Humans|*Eosinophilic Esophagitis|*Biopsies|Esophagus|Eosinophils|Proton Pump Inhibitors|Esophagitis, Peptic|Gastroesophageal Reflux|CCL26 protein, human|Chemokine CCL26|Leukocyte Count|Arachidonate 15-Lipoxygenase|ALOX15 protein, human 152 RETNLB 28801998 Med. Sci. Monit. 2017 PMC5565234 10.12659/msm.905381 4 19 0 201 Humans|*Mesangial Cells|*Mitogen-Activated Protein Kinases|*Diabetic Nephropathies|*Resistin|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|*Signal Transduction|p38 Mitogen-Activated Protein Kinases|Mitogen-Activated Protein Kinase 1|MAP Kinase Signaling System|Phosphorylation|Cell Proliferation|Transforming Growth Factor beta1|Cell Cycle|4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole|Pyridines|Imidazoles|Diabetes Mellitus 152 RETNLB 28041789 Exp. Cell Res. 2017 10.1016/j.yexcr.2016.12.021 0 7 0 201 Humans|*Focal Adhesion Kinase|*Pulmonary Artery|PTK2 protein, human|*Focal Adhesion Kinase 1|Smooth Muscle Cells|Muscle, Smooth, Vascular|Cell Proliferation|BIRC5 protein, human|Survivin|Hypertension, Pulmonary|Apoptosis|Cells, Cultured|Cell Cycle|Cell Hypoxia|Signal Transduction 152 RHBDF1 29081410 Cancer Biomark 2017 10.3233/CBM-170541 0 0 0 79 Humans|*Basal Cell Nevus Syndrome|*Whole Exome Sequencing|PTCH2 protein, human|Patched-2 Receptor|*Chinese|Patched-1 Receptor|Exome|Pedigree|Mutation|Genetic Linkage 30 RHBDF1 28104813 J. Cell. Sci. 2017 PMC5358332 10.1242/jcs.196436 5 2 0 79 Mice|Animals|*Proteolysis|ADAM17 protein, human|*ADAM-17|RHBDF2 protein, human|Carrier Proteins|ADAM Proteins|Membrane Protein|Tumor Necrosis Factor-alpha|Signal Transduction|EGFR protein, human|Epidermal Growth Factor Receptor|Mice, Knockout|Phosphorylation|Cell Line|*Models, Structural|Adam17 protein, mouse|iRhom2 protein, mouse 30 RIMS2 28600779 Hum. Genet. 2017 PMC5502059 10.1007/s00439-017-1821-8 39 1 0 81 Humans|*Exome|Saudi Arabia|Nerve Tissue Proteins|Endoplasmic Reticulum|Golgi Apparatus|Receptors, Immunologic|Vesicular Transport Proteins|Sequencing, Whole Exome|Genes, Recessive|Homozygote|Mutations|Sequencing, Next-Generation|Sequence Analysis, DNA|Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|GRSF1 protein, human 35 RIMS2 28377503 J. Biol. Chem. 2017 PMC5454116 10.1074/jbc.M117.778829 5 1 0 81 Calcium Channels, N-Type|Presynaptic Terminals|*RNA Splicing|Synaptic Transmission|Neurons|Nerve Tissue Proteins 35 RIMS2 28118666 Invest. Ophthalmol. Vis. Sci. 2017 10.1167/iovs.16-20705 8 0 0 81 Humans|*DNA Copy Number Variations|*Genome|*Retinal Disease|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Mutations 35 RNASEH1 29248492 J. Allergy Clin. Immunol. 2017 PMC6003829 10.1016/j.jaci.2017.11.023 3 2 0 176 Humans|*Wiskott-Aldrich Syndrome|*R-Loop Structures|WAS protein, human|Wiskott-Aldrich Syndrome Protein|Thrombocytopenia 1|Thrombocytopenia|*T-Lymphocytes, Helper-Inducer|Genetic Diseases, X-Linked|*Genomic Instability|Actins|Mutations|Transcription, Genetic|Cell Nucleus|Genes, X-Linked 47 RNASEH1 29204916 J. Endocrinol. Invest. 2017 10.1007/s40618-017-0797-5 1 0 0 176 *Diabetes Mellitus, Type 1|Colombia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Linkage Disequilibrium|Alleles|Genotype|Genetic Linkage 47 RNF39 28729889 Clin Epigenetics 2017 PMC5516341 10.1186/s13148-017-0371-1 14 1 0 8 DNA Methylation|HLA-DRB1 Chains|Epigenesis, Genetic|Multiple Sclerosis|Genetic Predisposition to Disease|Case-Control Studies 22 RNF39 28630453 Mol. Psychiatry 2017 PMC5984086 10.1038/mp.2017.120 21 2 0 8 Male|Humans|*Stress Disorders, Post-Traumatic|*Military Personnel|*Epigenome|Prospective Studies|Afghan Campaign 2001-|DNA Methylation|Epigenesis, Genetic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|RNF39 protein, human|Immediate-Early Proteins 22 RNF39 28149331 Clin Epigenetics 2017 PMC5270349 10.1186/s13148-017-0310-1 4 1 0 8 *Allergic Rhinitis|SNPs|Genome-Wide Association Study|Genetic Predisposition to Disease|Quantitative Trait Loci|Genotype|Immunoglobulin E|Phenotype|Promoter Regions, Genetic|Case-Control Studies|Asthma 22 RP1L1 29196766 Invest. Ophthalmol. Vis. Sci. 2017 10.1167/iovs.17-21969 0 0 0 12 Humans|*Macular Degeneration|Fluorescein Angiography|*Mutations|Electroretinography|*Retinal Dystrophies|Eye Proteins|Tomography, Optical Coherence|Visual Acuity|Pedigree|Phenotype|*Eye Abnormalities|RP1L1 protein, human 47 RP1L1 28890726 Front Genet 2017 PMC5574873 10.3389/fgene.2017.00107 1 1 0 12 47 RP1L1 28473427 BMJ Case Rep 2017 PMC5612209 10.1136/bcr-2016-218364 0 0 0 12 Humans|Male|Middle Aged|Retinitis pigmentosa 1|*Jews|*Retinitis Pigmentosa|*Macular Degeneration|Electroretinography|Fluorescein Angiography|Coherence Tomography, Optical|Eye Proteins|*Retinal Dystrophies|Vision Disorders|Visual Acuity|Mutation|Phenotype|*Eye Abnormalities|ERG protein, human|Transcriptional Regulator ERG|RP1L1 protein, human 47 RP1L1 28195981 Retin Cases Brief Rep 2017 10.1097/ICB.0000000000000548 0 0 0 12 Humans|*Macular Degeneration|Fluorescein Angiography|*Mutation|Electroretinography|*Retinal Dystrophies|Eye Proteins|Tomography, Optical Coherence|Visual Acuity|Phenotype|Pedigree|Vision Disorders|*Eye Abnormalities|RP1L1 protein, human 47 rrad 28989002 Mol. Cell. Neurosci. 2017 10.1016/j.mcn.2017.10.001 7 1 0 621 Humans|*Motor Cortex|*Salts|Neurodegenerative Diseases|*Spinal Cord|Amyotrophic Lateral Sclerosis|Motor Neurons|*Sodium Chloride|*Sodium Chloride, Dietary|Chitinases|Microglia|Prognosis|CHI3L1 protein, human|Chitinase-3-Like Protein 1|CHI3L2 protein, human 121 rrad 28732776 Bone 2017 PMC6886723 10.1016/j.bone.2017.07.018 3 0 0 621 Mice|Animals|*Bone Marrow|*Bone Density|*Adipose Tissue|Adipogenesis|Osteogenesis|Adipocytes|Osteoblasts|Mesenchymal Stem Cells|RRAD protein, human|*ras Proteins|Cell Differentiation|Rem2 protein, mouse|Monomeric GTP-Binding Proteins 121 rrad 28716111 BMC Cancer 2017 PMC5514474 10.1186/s12885-017-3482-3 6 6 0 621 *Nasopharyngeal Carcinoma|*Herpesvirus 4, Human|*DNA Methylation|hydrogen sulfite|Epstein Barr Virus Infection|Nasopharyngeal Neoplasms|Carcinoma|Epigenetic|Promoter Regions, Genetic|Epigenesis, Genetic|DNA, Viral|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|China 121 RTTN 28811500 Nat Commun 2017 PMC5558016 10.1038/s41467-017-00305-0 11 26 0 72 Humans|*Centrioles|*Microcephaly|rotatin protein, human|*Carrier Proteins|Centrosome|Cell Cycle Proteins|Intracellular Signaling Peptides and Proteins|Microtubule-Associated Proteins|Cell Cycle|Protein Binding|Mutation|HEK293 Cells|Electron Microscopy|STIL protein, human|POC1B protein, human 21 RTTN 28518170 Genet. Med. 2017 PMC5675748 10.1038/gim.2017.33 25 0 0 72 Pregnancy|Female|Humans|*Exome|*Whole Exome Sequencing|Prenatal Diagnosis|Fetus|Ultrasonography, Prenatal|Genetic Counseling|MAP4K4 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|DYNC2H1 protein, human|Cytoplasmic Dyneins 21 SALL3 28844110 Virchows Arch. 2017 10.1007/s00428-017-2224-x 0 0 0 122 *Chordoma|*Transcriptome|*Skull Base Neoplasms|*Spine|Notochord|Immunohistochemistry|Biomarkers, Tumor|*Head and Neck Neoplasms|Skull Base 61 SALL3 28794449 Nat Commun 2017 PMC5550436 10.1038/s41467-017-00235-x 9 50 0 122 Lymphoid Cells|Immunity, Innate|*Gene Expression Regulation|Cell Differentiation|Receptors, Interleukin-7|Cell Lineage|Interleukin-7 Receptor alpha Subunit|STAT5A protein, human|Tumor Suppressor Proteins|STAT5 Transcription Factor 61 SAMSN1 29187421 G3 (Bethesda) 2017 PMC5919749 10.1534/g3.117.300382 0 0 0 51 Animals|*Chickens|Genome-Wide Association Study|Egg Shell|Breeding|Haplotype|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Genotype|Phenotype|Pigmentation|*Color 25 SAMSN1 28927462 Stem Cell Res Ther 2017 PMC5606115 10.1186/s13287-017-0645-8 0 4 0 51 Humans|*Polycystic Kidney, Autosomal Dominant|*Induced Pluripotent Stem Cells|TRPP Cation Channels|*Kidney|*Cell Differentiation|Mutations 25 SAMSN1 28355232 PLoS ONE 2017 PMC5371323 10.1371/journal.pone.0173880 5 3 0 51 Humans|*Coronary Artery Disease|Air Pollution|European Continental Ancestry Group|African Americans|SNPs|Atherosclerosis|Genome-Wide Association Study|Genetic Predisposition to Disease|Environmental Exposure|*Ethnic Groups|Gene-Environment Interaction|Peripheral Arterial Disease|Myocardial Infarction|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport 25 SAMSN1 28148900 Oncotarget 2017 PMC5392284 10.18632/oncotarget.14846 8 7 0 51 *Immunoblastic Lymphadenopathy|*Mutation|Isocitrate Dehydrogenase|Lymphoma, T-Cell|Lymphoma, T-Cell, Peripheral|Proto-Oncogene Proteins|Helper T-Cells|DNA-Binding Proteins|DNA Methylation|rhoA GTP-Binding Protein|Biomarkers, Tumor|Phenotype|Taiwan 25 SAMSN1 28105178 Oncol Lett 2017 PMC5228349 10.3892/ol.2016.5233 0 0 0 51 Humans|*Prognosis|Neoplasm Recurrence, Local|Gastric Cancer|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|RNA, Messenger|Stomach 25 SBSN 29162406 Clin. Immunol. 2017 10.1016/j.clim.2017.11.006 0 0 0 57 Humans|*Lupus Vasculitis, Central Nervous System|Proteomics|Autoantibodies|Lupus Erythematosus, Systemic|Enzyme-Linked Immunosorbent Assay|Ribosomal Proteins|Complexes, Immune 23 SBSN 28910601 Psychoneuroendocrinology 2017 10.1016/j.psyneuen.2017.09.005 5 0 0 57 *Bipolar Disorder|*Depressive Disorder, Major|*Chromatography, Liquid|*Tandem Mass Spectrometry|*Computational Biology|*Biomarkers|Proteomics|*Plasma 23 SCAF1 29195136 Redox Biol 2017 PMC5723280 10.1016/j.redox.2017.11.017 11 17 0 104 Humans|oxidized low density lipoprotein|*Lipoproteins, LDL|Foam Cells|*Macrophages|CD36 Antigens|Atherosclerosis|Scavenger Receptors, Class A|Scavenger Receptors, Class E|ATP Binding Cassette Transporter, Subfamily G, Member 1|Receptors, Oxidized LDL|*Oxidative Stress|Biological Transport|Reactive Oxygen Species|Signal Transduction|Gene Expression|Cell Differentiation|*Biomarkers 28 SCAF1 28790391 Sci Rep 2017 PMC5548899 10.1038/s41598-017-08081-z 5 10 0 104 Mice|Animals|*Blood Glucose|*Mitochondria|Electron Transport Complex IV|Oxidative Phosphorylation|Mitochondrial Membranes|Mitochondrial Proteins|Insulin 28 SCAF1 28758667 Nanoscale 2017 10.1039/c7nr03254d 0 0 0 104 *Up-Regulation|CD36 Antigens|Scavenger Receptors, Class B|Receptors, Immunologic|Scavenger Receptors, Class A|Lipoproteins, LDL|*Biological Transport|Receptors, LDL|Lipoproteins, HDL|Cholesterol Esters|*Transcriptional Activation|Gene Expression|Downregulation|Cells, Cultured|*Nanoparticle 28 SCAF1 28705724 Fish Shellfish Immunol. 2017 10.1016/j.fsi.2017.07.025 2 1 0 104 Humans|Animals|*RNA, Double-Stranded|Type I Interferons|Scavenger Receptors, Class A|RNA, Viral|Cell Line|RNA Viruses|Antiviral Agents|Innate Immune Response|Viruses|Chinook Salmon|Scavenger Receptors 28 SCAMP2 29180230 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.11.020 16 0 0 316 *Glucocorticoids|Corticosterone|Receptors, Glucocorticoid|DUSP1 protein, human|Dual Specificity Phosphatase 1|Cortisol|CXXC5 protein, human|Carrier Proteins|Transcriptomes|Transcription Factors|Signal Transduction|Up-Regulation|*Nervous System Physiological Phenomena|mRNA|Brain 26 Scara3 28975986 Eur Rev Med Pharmacol Sci 2017 1 9 0 1145 Male|Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|1,1-dimethyl-4-acetylpiperazinium|Neoplasm Invasiveness|Phosphatidylinositol 3-Kinases|Cell Movement|Proto-Oncogene Proteins c-akt|Cell Proliferation|Downregulation|Hep G2 Cells|Signal Transduction|Apoptosis|*Neoplastic Processes|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Cells, B-1 37 Scara3 28363799 Neurobiol. Dis. 2017 PMC5439028 10.1016/j.nbd.2017.03.010 4 7 0 1145 Mice|Animals|Humans|neuroserpin|*Serpins|*Polymers|Familial encephalopathy with neuroserpin inclusion bodies|*Heredodegenerative Disorders, Nervous System|*Neuropeptides|*Epilepsies, Myoclonic|*Neurons|Endoplasmic Reticulum|Polymerization|Golgi Apparatus|Mutations|Proteasome|*Oxidative Stress|Animals, Genetically Modified|Cell Lines|Dementia 37 SCGB1D2 28634007 Am. J. Pathol. 2017 10.1016/j.ajpath.2017.03.012 5 0 0 18 Humans|*Carcinoma, Intraductal, Noninfiltrating|Carcinoma, Ductal, Breast|*Disease Progression|Gene Expression Profiling|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Immunohistochemistry|S100A7 protein, human|S100 Calcium Binding Protein A7|Microarray Analysis|Cluster Analysis|*Breast Neoplasms 156 SCGB1D2 28432361 Sci Rep 2017 PMC5430701 10.1038/s41598-017-00996-x 2 2 0 18 *Gene Regulatory Networks|Receptors, Estrogen|Tripartite Motif Proteins|Biomarkers, Tumor|Transcription Factors|Gene Expression Regulation, Neoplastic|coactivator-associated arginine methyltransferase 1|Protein-Arginine N-Methyltransferases|*Cancer|Ubiquitin-Protein Ligases|*Neoplasms, Second Primary|Disease Progression 156 SCPEP1 28520992 Nucleic Acids Res. 2017 PMC5570063 10.1093/nar/gkx440 9 72 0 445 Humans|*Heterogeneous-Nuclear Ribonucleoprotein L|MIRN574 microRNA, human|*MicroRNAs|mRNA|3' Untranslated Regions|*Tumorigenesis|*Cell Transformation, Neoplastic|Heterogeneous-Nuclear Ribonucleoproteins|Vascular Endothelial Growth Factor A|VEGFA protein, human 47 SCPEP1 28234994 PLoS ONE 2017 PMC5325571 10.1371/journal.pone.0172854 1 13 0 445 Humans|Mice|Animals|*Cathepsin A|serine carboxypeptidase|Carboxypeptidases|*Stromal Dystrophy, Corneal|Hypertension|Endothelin-1|*Lysosomes|Cultured Cells|Hemodynamics|Cell Proliferation|Scpep1 protein, mouse 47 SEC14L2 29232835 Int J Mol Sci 2017 PMC5751275 10.3390/ijms18122673 9 6 0 336 Pregnancy|Female|Humans|*Granulosa Cells|Oogenesis|Ovulation|Oligonucleotide Array Sequence Analysis|*Lipogenesis|Cells, Cultured|Real-Time Polymerase Chain Reaction 55 SEC14L2 31966469 Int J Clin Exp Pathol 2017 PMC6965858 0 0 0 336 Humans|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pulmonary Tuberculosis|Asian Continental Ancestry Group|Gene Frequency|Alleles|Genotype|Case-Control Studies|Odds Ratio 55 SEC14L2 28984238 J. Gen. Virol. 2017 PMC5725995 10.1099/jgv.0.000932 0 5 0 336 *Hepacivirus|Antiviral Agents|Hepatitis C, Chronic|*Replicon|Hepatitis C|Viral Nonstructural Proteins|Genotype|Virus Replication|Cell Line|*Genomics|*DNA Viruses|Sequencing, Next-Generation|Luciferase 55 SEC14L2 28463110 Elife 2017 PMC5423769 10.7554/eLife.26362 4 8 0 336 *GTPase|*Phospholipid Transfer Proteins|Frizzled Receptors|Wnt Proteins|Dishevelled Proteins|beta Catenin|Signal Transduction|Protein Binding|Trans-Activators 55 SEC14L2 28059487 J. Cell. Biochem. 2017 10.1002/jcb.25871 1 8 0 336 alpha-tocopherol phosphate|*Monocytes|*Vascular Endothelial Growth Factor A|*Phosphatidylinositol 3-Kinases|Amyloid beta-Peptides|*alpha-Tocopherol|*SR-BI Receptor|oxidized low density lipoprotein|Lipoproteins, LDL|*Vascular Endothelial Growth Factors|Tocopherol|Carrier Proteins|Lipids|Phosphorylation|Biological Transport|Signal Transduction|Scavenger Receptor|Phagocytosis 55 SERPINA6 29194043 J. Pediatr. Endocrinol. Metab. 2017 10.1515/jpem-2017-0270 5 0 0 697 Humans|Female|*Transcortin|Chromatography, Liquid|Tandem Mass Spectrometry|*Adrenal Insufficiency|Cortisol|Cortisone|Pituitary-Adrenal System|Hypothalamo-Hypophyseal System|Saliva|Immunoassay|Contraceptives, Oral 94 SERPINA6 29126409 BMC Cancer 2017 PMC5681795 10.1186/s12885-017-3722-6 1 2 0 697 Humans|Child|*Survivors|Metabolic Syndrome|Insulin Resistance|Obesity|Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Genomics|Hypertension|Dyslipidemia|*Complement Factor B|Risk Factors|Genetic Susceptibility 94 SERPINA6 28677244 J Appl Toxicol 2017 10.1002/jat.3497 0 1 0 697 Humans|Animals|*Plasticizers|phthalic acid|*Transcortin|*Phthalic Acids|*Endocrine Disruptors|Ligands|Protein Binding|*In Silico|Molecular Docking Simulation|Receptors, Steroid 94 SERPINA6 28611262 Ann Hepatol 2017 10.5604/01.3001.0010.0298 2 1 0 697 Humans|*Adrenal Insufficiency|Cosyntropin|Hydrocortisone|Liver Cirrhosis|Biomarkers|Prospective Studies|Risk Factors 94 SERPINA6 28411181 J. Steroid Biochem. Mol. Biol. 2017 10.1016/j.jsbmb.2017.04.005 0 1 0 697 Humans|Cattle|Animals|*Transcortin|*Proteolysis|ELANE protein, human|Neutrophil Elastase|Protein Binding|Pseudomonas aeruginosa|Antibodies, Monoclonal|*Hydrolases|Chymotrypsin|Cortisol|Half Life 94 SERPINB5 29176937 Clin Proteomics 2017 PMC5689177 10.1186/s12014-017-9168-7 4 2 0 751 *Proteomics|*Gene Expression Profiling|*Biomarkers|Fibroblasts|*Neoplasms, Fibrous Tissue|Tumor Microenvironment|Stromal Cells|Extracellular Matrix|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Cancer-Associated Fibroblasts|Transforming Growth Factor beta|Proteome|*Inflammation 102 SERPINB5 29029529 Oncotarget 2017 PMC5630429 10.18632/oncotarget.20192 3 13 0 751 Humans|*Stomach Neoplasms|SERPIN-B5|*Computational Biology|*Serpins|Adenocarcinoma|Gastric Mucosa|Neoplasm Staging|Genes, Tumor Suppressor|Biomarkers, Tumor|Serine Proteinase Inhibitors 102 SERPINB5 28980874 Cell Cycle 2017 PMC5788484 10.1080/15384101.2017.1380135 19 0 0 751 *Stomach Neoplasms|*mRNA|*RNA, Circular|*Oncogenes|MicroRNAs|Gene Expression Regulation, Neoplastic|Downregulation|Upregulation|Biomarkers, Tumor|Networks, Gene|ROC Curve|Cell Proliferation 102 SERPINB5 28687755 Sci Rep 2017 PMC5501852 10.1038/s41598-017-05280-6 10 7 0 751 Humans|*Epithelial-Mesenchymal Transition|*Colorectal Cancer|*Prognosis|Snail Family Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Movement|Cadherins|Signal Transduction|Cell Line, Tumor|Cell Proliferation|*Colonic Neoplasms|Tumor Microenvironment 102 SERPINB5 28612287 J. Endocrinol. Invest. 2017 10.1007/s40618-017-0702-2 2 0 0 751 *Methylation|*Thyroid Cancer|Thyroid Nodule|Adenocarcinoma, Follicular|Carcinoma, Papillary|Thyroid Cancer, Papillary|Carcinoma|Biomarkers, Tumor 102 SERPINB7 29106929 J. Invest. Dermatol. 2017 10.1016/j.jid.2017.10.014 1 3 0 30 Humans|*Nonsense Mediated mRNA Decay|*Codon, Nonsense|Palmoplantar Keratosis|Mutation|gentamicin B|*Gentamycin|Pedigree|Serpins|Asian Continental Ancestry Group|Skin|SERPINB7 protein, human 57 SERPINB7 28687745 Sci Rep 2017 PMC5501799 10.1038/s41598-017-04743-0 2 3 0 30 Humans|130-nm albumin-bound paclitaxel|*Capecitabine|Retrospective Studies|*Albumins|*Paclitaxel|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Deoxycytidine|Adenocarcinoma|Antineoplastic Combined Chemotherapy Protocols|Pancreas|Treatment Outcome|SERPINB7 protein, human|Serpins 57 SERPINB7 28671352 J. Orthop. Res. 2017 PMC5752630 10.1002/jor.23644 10 0 0 30 Swine|Animals|*Cartilage, Articular|Anterior Cruciate Ligament|Anterior Cruciate Ligament Reconstruction|Anterior Cruciate Ligament Injuries|Osteoarthritis, Knee|Knee Joint|Swine, Miniature|Synovial Membrane|MMP1 protein, human|Matrix Metalloproteinase 1 57 SERPINB9 28743062 Diabetes Res. Clin. Pract. 2017 10.1016/j.diabres.2017.07.013 1 1 0 198 Humans|perforin-granzyme B|*Granzymes|*Perforin|*Coronary Artery Disease|*Insulin Resistance|Diabetes Mellitus, Type 2|*Serine Proteinase Inhibitors|*Recombinant Fusion Proteins|*Inflammation|*Leukocytes|*Gene Expression|Atherosclerosis|Serpins|SERPINB9 protein, human 133 SERPINB9 28722018 Immunol. Cell Biol. 2017 10.1038/icb.2017.59 5 2 0 198 Mice|Animals|GZMB protein, human|*Granzymes|*Natural Killer Cells|Serpins|*Poxvirus Infection|Cell Death|*Serine Proteinase Inhibitors|Knockout Mouse|Lysosome|Serpinb9 protein, mouse|Membrane Proteins 133 SERPINB9 28553232 Front Physiol 2017 PMC5427114 10.3389/fphys.2017.00261 7 6 0 198 Humans|Male|*DNA Methylation|*Oligospermia|CpG Islands|Epigenetic|Epigenesis, Genetic|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|*Biochemical Phenomena|RNA, Messenger 133 SERPINB9 28522562 Am. J. Physiol. Lung Cell Mol. Physiol. 2017 10.1152/ajplung.00322.2016 1 6 0 198 Humans|Female|*Particulate Matter|Phosphatidylinositol 3-Kinases|Glycogen Synthase Kinase 3|*Estrogens|*Lung Adenocarcinoma|Oestradiol|*Receptors, Estrogen|Estrogen Receptor alpha|Signal Transduction|Phosphorylation|Lung Cancer|*Smoke|Cell Line, Tumor|EGFR protein, human|Epidermal Growth Factor Receptor|siRNA|Cell Proliferation 133 SERPINI1 28747664 Sci Rep 2017 PMC5529435 10.1038/s41598-017-06811-x 0 0 0 165 *Mutations|*Brain Neoplasms|High-Throughput Nucleotide Sequencing 31 SERPINI1 28631894 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38317 0 0 0 165 Adult|Child|Humans|*Epilepsy, Progressive Myoclonic|*Unverricht-Lundborg Syndrome|Phenotype|Pedigree|Muscular Atrophy, Spinal|Mutation|Brain 31 SERPINI1 28229167 Thromb. Haemost. 2017 10.1160/TH16-07-0572 2 2 0 165 Humans|SERPINE1 protein, human|*Plasminogen Activator Inhibitor 1|*Glycine|*Mutation|Protein Conformation|Protein Binding|Binding Sites|Thrombin|Amino Acid Substitution|Mutagenesis|Mutagenesis, Site-Directed|Amino Acid Sequence|Kinetics|Tissue Plasminogen Activator|Models, Molecular|Homozygote|neuroserpin|Serpins 31 SFMBT2 29129685 Stem Cell Reports 2017 PMC5785679 10.1016/j.stemcr.2017.10.009 8 15 0 127 *MicroRNAs|*Sequencing, RNA|Embryonic Stem Cells|Cell Differentiation|*Base Sequence|Genomic Imprinting|Iodide Peroxidase|*Whole Exome Sequencing|Calcium-Binding Proteins 46 SFMBT2 29121352 Toxicol. Sci. 2017 PMC6693399 10.1093/toxsci/kfx241 2 2 0 127 Mice|Animals|Mirn466 microRNA, mouse|*Arsenic|MIRN92 microRNA, human|*MicroRNAs|NeuroD protein|*Basic Helix-Loop-Helix Transcription Factors|*Nerve Tissue Proteins|Cell Differentiation|Neurogenesis|sodium arsenite|Arsenites|Sodium Compounds|Transcription Factors|Cell Line|Neurod1 protein, mouse|Sfmbt2 protein, mouse 46 SFMBT2 28943493 EuroIntervention 2017 10.4244/EIJ-D-17-00180 3 0 0 127 Plaque, Atherosclerotic|*Atherosclerosis|Coronary Atherosclerosis|Coronary Angiography|Coronary Vessels|Ultrasonography, Interventional|*Inflammation|Acute Coronary Syndrome|*Vascular Remodeling|Biomarkers|Risk Factors|*Ultrasonography 46 SFMBT2 28653903 Tumour Biol. 2017 10.1177/1010428317707374 4 11 0 127 Humans|*RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Cell Proliferation|MCF-7 Cells|Cell Movement|Apoptosis|Transcriptional Activation 46 SFMBT2 28467908 Cell Rep 2017 10.1016/j.celrep.2017.04.018 0 0 0 127 Female|Mice|Pregnancy|Animals|*RNA, Micro|*Rodent|*Placental Development|Trophoblast|Placenta|Genomic Imprinting|Transcription Factors|Intron|Allele|Multigene Family|Gene Expression|Sfmbt2 protein, mouse 46 SH3PXD2B 29100834 J AAPOS 2017 10.1016/j.jaapos.2017.07.216 0 0 0 105 Humans|Child|Ter Haar syndrome|*Siblings|*Craniofacial Abnormalities|*Osteochondrodysplasias|*Heart Defects, Congenital|*Developmental Disabilities|Homozygote|Adaptor Proteins, Signal Transducing|Mutation 23 SH3PXD2B 29025412 BMC Genomics 2017 PMC5639760 10.1186/s12864-017-4201-9 13 9 0 105 Swine|Animals|*Transcriptome|*Epigenome|Breeding|Meat|*Paraspinal Muscles|Phenotype|Gene Expression Profiling|Adipose Tissue|Genome|Fatty Acids|Lipid Metabolism|China 23 SH3PXD2B 28728367 Asian-australas. J. Anim. Sci. 2017 PMC5666187 10.5713/ajas.17.0154 4 1 0 105 Animals|Sheep|*DNA Methylation|*Genome|CpG Islands|Epigenesis, Genetic|Sequence Analysis, DNA|*DNA|*Sheep, Domestic|Muscle, Skeletal 23 SH3PXD2B 28694206 Gene 2017 10.1016/j.gene.2017.07.011 5 0 0 105 Humans|Child|Ter Haar syndrome|*Exome|*Craniofacial Abnormalities|*Osteochondrodysplasias|*Heart Defects, Congenital|*Developmental Disabilities|*Whole Exome Sequencing|Eye Abnormalities|Abnormalities, Multiple|Hypertelorism|Mutations|Adaptor Proteins, Signal Transducing 23 SHROOM2 28117766 J Vis Exp 2017 PMC5409187 10.3791/54886 0 0 0 47 *Crystallization|Protein Structure, Tertiary|Amino Acid Sequence|Membrane Proteins|Sequence Alignment|Protein Binding|Cloning, Molecular|*Protein Domains|Models, Molecular|Escherichia coli 26 SIDT2 28785058 Sci Rep 2017 PMC5547113 10.1038/s41598-017-07077-z 3 5 0 73 Animals|Caenorhabditis elegans|*Membrane Proteins|Caenorhabditis elegans Proteins|*Biological Transport|RNA Transport|*Mammals|Membrane Transport Proteins|RNA|Cholesterol|*Biochemical Phenomena|Cholesterol, Dietary|Animals|Caenorhabditis elegans|*Membrane Proteins|Caenorhabditis elegans Proteins|*Biological Transport|RNA Transport|*Mammals|Membrane Transport Proteins|RNA|Cholesterol|*Biochemical Phenomena|Cholesterol, Dietary 25 SIDT2 28916264 Immunity 2017 PMC5679266 10.1016/j.immuni.2017.08.007 17 12 0 73 Mice|Animals|*RNA, Double-Stranded|Encephalomyocarditis virus|*Cytoplasm|Cardiovirus Infections|Herpes Simplex Virus 1|RNA, Viral|Immunity, Innate|RNA Transport|Cell Line|Caenorhabditis elegans|Signal Transduction|Sidt2 protein, mouse|Membrane Proteins|SID-1 protein, C elegans|Caenorhabditis elegans Proteins 25 SIDT2 28724756 J. Cell. Sci. 2017 10.1242/jcs.202481 2 3 0 73 Humans|*Lysosomes|RNA|Lysosomal-Associated Membrane Protein 2|Membrane Proteins|Protein Transport|HeLa Cells|Autophagy|RNA Degradation|SIDT2 protein, human|Nucleotide Transport Proteins 25 SIDT2 28277980 RNA Biol 2017 PMC5785214 10.1080/15476286.2017.1302641 5 5 0 73 Humans|Animals|*Oligonucleotides|*Biological Transport|RNA Transport|Nucleotide Transport Proteins|Lysosomes|Caenorhabditis elegans|Oligonucleotides, Anti-Sense|Double-Stranded RNA|Membrane Proteins|Protein Binding|Transfection|RNA Interference|SIDT2 protein, human|SID-1 protein, C elegans|Caenorhabditis elegans Proteins 25 Sigmar1 29164477 J. Mol. Neurosci. 2017 10.1007/s12031-017-1002-1 1 0 0 1064 *Antipsychotic Agents|*Schizophrenia|Single Nucleotide Polymorphisms|*Psychopathology|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Italy 92 SIM2 29109451 Sci Rep 2017 PMC5674005 10.1038/s41598-017-15261-4 0 8 0 147 Humans|Female|*Uterine Cervical Neoplasms|Retrospective Studies|*Carcinoma, Squamous Cell|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|*Hypoxia|Basic Helix-Loop-Helix Transcription Factors|Neovascularization, Pathologic|Biomarkers, Tumor|*Uterus|SIM2 protein, human 122 SIM2 28910345 PLoS ONE 2017 PMC5598937 10.1371/journal.pone.0184094 19 0 0 147 Humans|Male|*MicroRNAs|*mRNA|kallikrein-related peptidase 3, human|Prostate Specific Antigen|*Prostate Cancer|*Prognosis|Kallikreins|Gleason Score|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Neoplasm Staging|Bone Neoplasms|Real-Time Polymerase Chain Reaction|Specificity|SIM2 protein, human|Basic Helix-Loop-Helix Transcription Factors|OR51E2 protein, human|Neoplasm Proteins 122 SKA3 29268205 Psychiatry Res 2017 10.1016/j.psychres.2017.12.024 0 0 0 193 Humans|*Glucocorticoids|*Kinetochore|*Pituitary-Adrenal System|*Hypothalamo-Hypophyseal System|Adrenocorticotropic Hormone|Corticosterone|*Gene Expression|Stress, Physiological|Neurons 37 SKA3 28982702 Biol Open 2017 PMC5703607 10.1242/bio.026930 9 35 0 193 *Kinetochores|Microtubules|polo-like kinase 1|Cell Cycle Proteins|AURKB protein, human|Aurora Kinase B|Anaphase|Chromosome Segregation|Spindle Apparatus|Metaphase|Mitosis|NUF2 protein, human|Microtubule-Associated Proteins|Chromosomal Proteins, Non-Histone|RPS27 protein, human|Nuclear Proteins|cdk1 Kinase|Protein Phosphatase 1 37 SKA3 28495837 J. Cell Biol. 2017 PMC5461014 10.1083/jcb.201607096 18 8 0 193 Humans|*Kinetochores|Chromosome Segregation|Microtubules|Spindle Apparatus|Chromosomal Proteins, Non-Histone|Mitosis|Microtubule-Associated Proteins|Cell Cycle Proteins|Protein-Serine-Threonine Kinases|Nuclear Proteins|Cytoskeletal Proteins|HeLa Cells 37 SKA3 28479321 Curr. Biol. 2017 10.1016/j.cub.2017.03.060 21 25 0 193 *Kinetochores|*Phosphorylation|*CDC2 Protein Kinase|Chromosome Segregation|Microtubules|NDC80 protein, human|*Nuclear Proteins|Anaphase|AURKB protein, human|Aurora Kinase B|Mitosis|Microtubule-Associated Proteins|Chromosomal Proteins, Non-Histone|Protein Phosphatase 1|Protein Binding 37 SKOR1 28329290 Sleep 2017 10.1093/sleep/zsx028 7 0 0 30 Humans|*Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Homeodomain Proteins|Transcription Factors|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Neoplasm Proteins|Case-Control Studies|*Chinese|MAP2K5 protein, human|BTBD9 protein, human 24 SLC16A12 29088427 Hum. Mol. Genet. 2017 10.1093/hmg/ddx310 5 2 0 24 Animals|Humans|*Creatine|HEK293 Cells|SLC6A8 protein, human|Plasma Membrane Neurotransmitter Transport Proteins|*Cataract|*Molecular Chaperones|creatine transporter|Monocarboxylic Acid Transporters|*Mutations|Nerve Tissue Proteins|Lens, Crystalline|Xenopus laevis|Biological Transport|Oocyte|*Ion Transport 24 SLC16A12 28596594 Sci Rep 2017 PMC5465184 10.1038/s41598-017-03294-8 1 5 0 24 *Helicobacter pylori|*Gastric Mucosa|Helicobacter Infections|*Narrowband Imaging|Gastritis|CpG Islands|DNA Methylation|Promoter Regions, Genetic|Stomach Neoplasms|*Epigenetic|Anti-Bacterial Agents|Epigenesis, Genetic 24 SLC16A12 28557342 Cancer Med 2017 PMC5504328 10.1002/cam4.1082 2 1 0 24 *Helicobacter pylori|*DNA Methylation|*Gastric Mucosa|Helicobacter Infections|Gastritis|CpG Islands|Stomach Neoplasms|Narrowband Imaging|Promoter Regions, Genetic|Metaplasia|*Disease Progression 24 SLC16A12 28540987 Yonsei Med. J. 2017 PMC5447105 10.3349/ymj.2017.58.4.749 7 0 0 24 *Colorectal Cancer|CpG Islands|ras Proteins|Microsatellite Instability|Proto-Oncogene Proteins B-raf|DNA Methylation|Proto-Oncogene Proteins|Mutation|Phenotype|*Colonic Neoplasms 24 SLC16A9 29030588 Sci Rep 2017 PMC5640623 10.1038/s41598-017-13451-8 3 0 0 89 Humans|Female|Rats|Animals|Infant, Newborn|*Non-alcoholic Fatty Liver Disease|*Testosterone|*Amino Acids, Branched-Chain|Polycystic Ovary Syndrome|Insulin Resistance|Liver|estradiol 3-benzoate|Oestradiol|*Testosterone Congeners 30 SLC16A9 28254523 Chem. Biol. Interact. 2017 PMC5725231 10.1016/j.cbi.2017.02.013 3 6 0 89 Mice|Animals|Uric Acid|*Transcriptome|Gout|Sodium-Phosphate Cotransporter Proteins, Type I|Hyperuricemia|*Mice, Knockout|Kidney|Kidney Tubules, Proximal|*Transcriptome Analysis|Mutation, Missense|*Metabolomics|*Urinary Tract Physiological Phenomena|*Plasma 30 SLC22A9 28385546 J Pharm Sci 2017 10.1016/j.xphs.2017.03.026 2 0 0 139 Humans|Female|Pregnancy|levocetirizine|*Cetirizine|*Biological Transport|Organic Anion Transporters, Sodium-Independent|Syncytiotrophoblasts|Histamine H1 Antagonists, Non-Sedating|Placenta|Organic Anion Transporters|Estrone|Tubules, Proximal Renal 30 SLC25A24 29100094 Am. J. Hum. Genet. 2017 PMC5673633 10.1016/j.ajhg.2017.09.017 13 3 0 148 Humans|Progeroid Syndrome, Congenital, Petty Type|Progeria|Mitochondria|Mitochondrial Proteins|Membrane Potential, Mitochondrial|Calcium-Binding Proteins|Antiporters|*Dysplasia, Bone|Adenosine Triphosphate|Mutations|*Aging|Oxygen Consumption|Fibroblasts|Growth Disorders|SLC25A24 protein, human 27 SLC25A24 29100093 Am. J. Hum. Genet. 2017 PMC5673623 10.1016/j.ajhg.2017.09.016 16 1 0 148 Humans|Female|Facial Hypertrichosis|Gorlin Chaudhry Moss syndrome|*Hypertrichosis|*Craniosynostoses|Progeroid syndrome, neonatal|Progeria|Craniofacial Abnormalities|Abnormalities, Multiple|Ductus Arteriosus, Patent|Mitochondrial Proteins|Antiporters|Syndrome|Exome|Calcium-Binding Proteins|Lipodystrophy|Fetal Growth Retardation|Mitochondria|Mutation 27 SLC25A24 28712724 Mol. Cell 2017 10.1016/j.molcel.2017.06.013 13 1 0 148 acylglycerol kinase|Cataract and cardiomyopathy|*Phosphotransferases (Alcohol Group Acceptor)|*Cataracts|*Cardiomyopathies|*Mitochondria|Mitochondrial Membranes|Mitochondrial Membrane Transport Proteins|*Carrier Proteins|Mutations|Protein Transport|Phenotype|Phospholipids 27 SLC25A24 28350015 Sci Rep 2017 PMC5369052 10.1038/srep45383 7 8 0 148 Humans|*Calcium|ATP-Mg-Pi carrier proteins, mitochondria|*Mitochondrial Proteins|*Antiporters|*Mitochondria|Mitochondrial Membrane Transport Proteins|*Calcium, Dietary|Adenosine Triphosphate|Calcium-Binding Proteins|Cytosol|SLC25A24 protein, human 27 SLC25A38 29139060 Int. J. Hematol. 2017 10.1007/s12185-017-2368-0 3 0 0 20 Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Genetic Diseases, X-Linked|5-Aminolevulinate Synthetase|*Cells, Erythroid|Mutation|Iron 35 SLC25A38 28772256 Blood Cells Mol. Dis. 2017 10.1016/j.bcmd.2017.07.003 1 0 0 20 Child|Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|Retrospective Studies|*Genetic Diseases, X-Linked|5-Aminolevulinate Synthetase|*Mutation|Iron Overload|Phenotype|Mitochondrial Membrane Transport Proteins|ALAS2 protein, human|Slc25a38 protein, human 35 SLC25A38 28740143 Sci Rep 2017 PMC5524794 10.1038/s41598-017-06527-y 3 7 0 20 Animals|Female|Humans|*Nicarbazin|protoporphyrin IX|*Chickens|*Down-Regulation|*Protoporphyrins|Eggshell|*Oviducts|Pigmentation|Color|Slc25a38 protein, human|Mitochondrial Membrane Transport Proteins 35 SLC25A38 28404662 G3 (Bethesda) 2017 PMC5473764 10.1534/g3.117.041194 1 13 0 20 Humans|Mitochondrial Membrane Transport Proteins|Saccharomyces cerevisiae|Mitochondria|Haem|Hemoglobin|Glycine|Multigene Family|*Epistasis, Genetic|Mutations|Slc25a38 protein, human 35 SLC31A2 28737129 Int J Clin Pharmacol Ther 2017 10.5414/CP202907 9 0 0 125 Humans|Female|*Carcinoma, Ovarian Epithelial|*Platinum|ATP7A protein, human|*Copper-Transporting ATPases|*Ovarian Neoplasms|Cisplatin|Organoplatinum Compounds|Drug Resistance, Neoplasm|Carboplatin|Antineoplastic Agents|Cation Transport Proteins|Adenosine Triphosphatases|*Genetic Polymorphisms|ATP7A protein, human (2-79)|Peptide Fragments 28 SLC31A2 28507097 J. Biol. Chem. 2017 PMC5500815 10.1074/jbc.M117.793356 7 0 0 125 Animals|*Copper Transport Proteins|*Gene Duplication|Cation Transport Proteins|Copper|Amino Acid Sequence|SLC31 Proteins|Eukaryotes|*Biological Evolution|Copper Transporter 1 28 SLFN12 29107068 Exp. Cell Res. 2017 10.1016/j.yexcr.2017.10.032 9 1 0 86 Humans|*Cyclic Nucleotide Phosphodiesterases, Type 3|PDE3 Inhibitors|zardaverine|Pyridazines|quazinone|Quinazolines|Gastrointestinal Stromal Tumors|Cell Line, Tumor|*B Cells|Drug Delivery Systems|mRNA|Gene Expression 24 SLFN12 28755526 Allergy 2017 10.1111/all.13263 6 2 0 86 *Allergic Rhinitis|Pollen|Rhinitis, Allergic, Seasonal|Nasal Provocation Tests|Allergens|Immunoglobulin E|Nasal Mucosa|*Environmental Exposure|Biomarkers|*Epigenesis, Genetic 24 SLFN12 28454120 Oncotarget 2017 PMC5522287 10.18632/oncotarget.17010 6 16 0 86 Humans|Animals|Mice|*Gastrointestinal Stromal Tumors|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Interstitial Cells of Cajal|*Prospective Studies|Imatinib|Proto-Oncogene Proteins c-kit|Antineoplastic Agents|Cell Line, Tumor|Drug Resistance, Neoplasm|Viability, Cell|Pyrimidines|Gene Expression Regulation, Neoplastic|Signal Transduction|Pde3a protein, mouse 24 SMARCAD1 29284678 J. Biol. Chem. 2017 PMC5827453 10.1074/jbc.RA117.000959 5 2 0 367 Humans|Mice|Animals|*Chromatin Assembly and Disassembly|Tripartite Motif-Containing Protein 28|Chromatin|Mouse Embryonic Stem Cells|Zinc Finger|DNA-Binding Proteins|Repressor Proteins|Heterochromatin|Protein Binding|Embryonic Stem Cells|ATPase|Protein Domains|Ubiquitin|SMARCAD1 protein, human|DNA Helicases 50 SMARCAD1 29269196 J. Pediatr. 2017 10.1016/j.jpeds.2017.11.011 0 0 0 367 *Heterozygote|Ectodermal Dysplasia|Nails, Malformed|Fingerprints, Absence of|Skin Diseases, Genetic|Pedigree|DNA Helicases|Mutation 50 SMPDL3B 29081073 Pediatr Int 2017 10.1111/ped.13355 2 0 0 44 Child|Adult|Humans|*Nephrotic Syndrome|*Sphingomyelin Phosphodiesterase|Rituximab|Focal Segmental Glomerulosclerosis|Minimal Change Nephrotic Syndrome|Immunologic Factors|Podocytes|Antigens, CD20|Kidney Diseases|Glucocorticoids|Efficacy, Clinical 23 SNX10 29090071 Avicenna J Med Biotechnol 2017 PMC5650739 1 0 0 57 Osteopetrosis|Pedigree|Mutation|Sorting Nexins|Osteoclast 51 SNX10 29034896 Stem Cell Res 2017 10.1016/j.scr.2017.07.024 0 0 0 57 Humans|*Osteopetrosis|*Induced Pluripotent Stem Cells|*Mutation|Sorting Nexins|Homozygote|Amino Acid Sequence|Osteoclasts|SNX10 protein, human 51 SORCS2 28827148 J. Mol. Biol. 2017 10.1016/j.jmb.2017.08.006 2 1 0 141 Animals|Cricetinae|Diabetes Mellitus, Type 2|Receptors, Cell Surface|Ligands|Nerve Tissue Proteins|Membrane Transport Proteins|Adaptor Proteins, Vesicular Transport|*Neuroreceptors|Protein Transport|Post-Translational Modifications|Alzheimer Disease|CHO Cells 54 SORCS2 28469074 JCI Insight 2017 PMC5414556 10.1172/jci.insight.88995 5 4 0 141 Humans|Mice|Animals|*Huntington Disease|HTT protein, human|Huntingtin Protein|Corpus Striatum|Synapses|N-methyl D-aspartate receptor subtype 2A|Receptors, N-Methyl-D-Aspartate|Neurons|Mice, Transgenic|Neostriatum|Nerve Tissue Proteins|Disease Models, Animal|*Protein Transport|SORCS2 protein, human|Receptors, Cell Surface|SorCS2 protein, mouse 54 SORCS2 28346477 PLoS Genet. 2017 PMC5386298 10.1371/journal.pgen.1006692 3 1 0 141 Mice|Animals|*Hair Cells, Auditory|Stereocilia|Inner Hair Cells|Cochlea|Mice, Transgenic|Cilia|sortilin|Adaptor Proteins, Vesicular Transport|Vestibule, Labyrinth|SorCS2 protein, mouse|Nerve Tissue Proteins|Receptors, Cell Surface 54 SORCS2 28068899 BMC Genomics 2017 PMC5223358 10.1186/s12864-016-3473-9 6 1 0 141 Child|Child, Preschool|Humans|*Body Mass Index|*Saliva|*Obesity|CpG Islands|DNA Methylation|Processes, Epigenetic|Epigenetic|Genome-Wide Association Study|*Hispanic 54 sp110 29094286 Transgenic Res. 2017 10.1007/s11248-017-0049-7 9 0 0 198 Animals|Cattle|Female|Swine|Sheep|Mice|Rats|*Gene Editing|*Livestock|Breeding|Genome|Animals, Genetically Modified|CRISPR|Genetic Engineering|Goats|Sp110 protein, mouse|Nuclear Proteins|Minor Histocompatibility Antigens 84 sp110 29046350 J. Biol. Chem. 2017 PMC5733578 10.1074/jbc.M117.796839 4 0 0 198 *Hepatitis B virus|*Nuclear Protein|hepatitis B virus X protein|*Trans-Activators|Promyelocytic Leukemia Protein|DNA, Viral|Hepatitis B Virus Infection|*Cell Nucleus|Virus Replication|Transcription Factors|Hepatocytes|Host-Pathogen Interactions|Innate Immune Response|Hepatocellular Carcinoma|*Intranuclear Inclusion Bodies|*Complement Factor B|Hep G2 Cells|SUMO-1 Protein 84 sp110 28969051 Oncotarget 2017 PMC5609983 10.18632/oncotarget.19300 0 69 0 198 Mice|Animals|*Macrophage|Tuberculosis|Mycobacterium tuberculosis|Sp110 protein, mouse|Minor Histocompatibility Antigens|Nuclear Proteins|Apoptosis|Endoplasmic Reticulum 84 sp110 28825155 J. Clin. Immunol. 2017 PMC6069968 10.1007/s10875-017-0431-5 3 0 0 198 Humans|*Flow Cytometry|*Immunologic Deficiency Syndromes|Immunodeficiency, Severe Combined|Hepatic Veno-Occlusive Disease|Minor Histocompatibility Antigens|Nuclear Proteins|Mutations|*Vascular Diseases|Sp110 protein, human 84 SPAG16 28137312 BMC Mol. Biol. 2017 PMC5282894 10.1186/s12867-017-0082-3 1 10 0 28 Animals|Humans|Mice|Male|Microtubule Proteins|*Gene Expression Regulation|SOXD Transcription Factors|Isoforms|Microtubule-Associated Proteins|Promoter Regions, Genetic|Binding Sites|Spermatozoa|SOX5 protein, human|Sox5 protein, mouse 28 SPAG6 29282908 Zhonghua Nan Ke Xue 2017 0 1 0 61 59 SPAG6 28819108 Sci Rep 2017 PMC5561245 10.1038/s41598-017-08739-8 2 6 0 61 59 SPATA16 29065458 Int J Mol Sci 2017 PMC5666888 10.3390/ijms18102208 10 5 0 7 Male|Mice|Animals|Humans|*Teratozoospermia|*CRISPR-Cas Systems|*Sperm|Infertility, Male|Mutations|Homozygote|Vesicular Transport Proteins|Point Mutation|Membrane Proteins|Genetic Testing|*CRISPR|Gene Deletion|SPATA16 protein, human 33 SPATA16 28355295 PLoS ONE 2017 PMC5371343 10.1371/journal.pone.0174642 4 1 0 7 Adult|Humans|Genome-Wide Association Study|*Risk Factors|Republic of Korea|*Pulmonary Tuberculosis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Gene Frequency|Haplotypes|Case-Control Studies|Alleles|Genotype|Logistic Models 33 SPEF2 29253229 Poult. Sci. 2017 10.3382/ps/pex345 2 0 0 21 Animals|*Chickens|*Feathers|Avian Leukosis Virus|Avian Leukosis|Poultry Diseases|Genes, Viral|Sex Chromosomes|Phenotype|Prolactin Receptor 34 SPEF2 28619825 Development 2017 10.1242/dev.152108 11 4 0 21 Humans|Male|*Spermatids|Sperm Tail|Spermatogenesis|*Microtubule|Sperm|Testis|Infertility, Male|Protein Transport|*Cell Differentiation|Cell Nucleus 34 SPEF2 28574850 Oncotarget 2017 PMC5546438 10.18632/oncotarget.17959 5 1 0 21 Humans|Child|*Asparaginase|*Whole Exome Sequencing|*Risk Factors|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|SNPs|Antineoplastic Agents|*Complement Factor B|Genetic Predisposition to Disease|Pancreatitis|Alleles|Genotype|3'-(1-butylphosphoryl)adenosine|Exome|Cohort Studies|Thrombosis|Quebec 34 SPOCK2 28794177 J. Clin. Microbiol. 2017 PMC5625392 10.1128/JCM.00467-17 14 0 0 42 Humans|Proteomics|Bayes Theorem|*Pulmonary Tuberculosis|*Tuberculosis|Mycobacterium tuberculosis|Antigens, Bacterial|*Serum Marker|Sputum|Sensitivity and Specificity|Blood Proteins 35 SPOCK2 28540987 Yonsei Med. J. 2017 PMC5447105 10.3349/ymj.2017.58.4.749 7 0 0 42 *Colorectal Cancer|CpG Islands|ras Proteins|Microsatellite Instability|Proto-Oncogene Proteins B-raf|DNA Methylation|Proto-Oncogene Proteins|Mutation|Phenotype|*Colonic Neoplasms 35 SPOCK2 28103583 Oncotarget 2017 PMC5386638 10.18632/oncotarget.14722 3 4 0 42 Humans|Infant|Infant, Newborn|*Bronchopulmonary Dysplasia|Preterm Infants|*Matrix Metalloproteinases|Lung|*Morphogenesis|Downregulation|Thrombospondin 1|Upregulation|Matrix Metalloproteinase 9|Genes, Regulator|TIMP2 protein, human|TIMP-2 35 srpx 28478503 Acta Neuropathol. 2017 10.1007/s00401-017-1720-z 7 9 0 33 Amyloid beta-Peptides|Proteomics|*Cerebral Amyloid Angiopathy|Senile Plaques|Alzheimer Disease|Apolipoproteins E|Peptide Fragments|*Synapsins|Brain|Smooth Muscle Cells|Cerebral Hemorrhage|Arterioles|Case-Control Studies 50 srpx 28184944 Oncol. Rep. 2017 10.3892/or.2017.5433 3 7 0 33 *miRNA|*mRNA|*Urinary Bladder Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Downregulation|Apoptosis Regulatory Proteins|Cell Transformation, Neoplastic|Disease Progression 50 srpx 28130869 Proteomics 2017 10.1002/pmic.201600333 2 0 0 33 Pregnancy|Female|Humans|*Follicular Fluid|*Proteomics|*Fertilization in Vitro|*Ovary|Ovarian Follicle|Proteome|Mass Spectrometry 50 STEAP4 29080328 Clin. Exp. Immunol. 2017 PMC5801491 10.1111/cei.13076 0 0 0 257 Humans|Male|Mice|Animals|TNF protein, human|Tumor Necrosis Factor alpha|Arthritis, Rheumatoid|Monocytes|NF-kappa B|Membrane Proteins|Lipopolysaccharides|Signal Transduction|*RNA Splicing|Inflammation|STEAP4 protein, human|Oxidoreductases 89 STEAP4 29078383 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5692584 10.1073/pnas.1712946114 0 2 0 257 Humans|Male|Mice|Animals|*Proteomics|*Inflammation|*Colon Cancer|Colitis|Colon|Inflammatory Bowel Disease|Colorectal Cancer|ferric citrate iron reductase|FMN Reductase|Homeostasis|Reactive Oxygen Species|Iron|Mitochondria|Disease Models, Animal|Cell Transformation, Neoplastic|Membrane Proteins|Tumorigenesis|STEAP4 protein, human 89 STEAP4 28981677 Carcinogenesis 2017 PMC5862336 10.1093/carcin/bgx078 0 1 0 257 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*DNA Methylation|Case-Control Studies|*B-DNA|Prospective Studies|Genes, p16|Promoter Regions, Genetic|Biomarkers, Tumor|AUC|Tumor Suppressor Proteins|ROC Curve|Cohort Studies|Polymerase Chain Reaction 89 STEAP4 28874710 Sci Rep 2017 PMC5585339 10.1038/s41598-017-10335-9 0 4 0 257 Animals|*Silver Carp|*Microcystis|*RNA-Seq|High-Throughput Nucleotide Sequencing|Sequence Analysis, RNA|Gene Expression Profiling|miRNAs|Transcriptome|Molecular Sequence Annotation|*Whole Exome Sequencing|Fish Diseases|*Liver 89 STEAP4 28677334 Anim. Genet. 2017 10.1111/age.12572 0 0 0 257 Sheep|Animals|*Genome-Wide Association Study|Sheep, Domestic|Breeding|Genotype|Phenotypes|SNPs|Gene Frequency|Genetic Association Studies|Gene Annotation 89 STEAP4 28583230 Allergy Rhinol (Providence) 2017 PMC5468759 10.2500/ar.2017.8.0199 0 3 0 257 Humans|*MicroRNAs|*Chronic Urticaria|Pilot Projects|Gene Expression Profiling|Signal Transduction|Cell Cycle|*Hives|Biomarkers 89 STEAP4 28576871 J. Endocrinol. 2017 PMC6166870 10.1530/JOE-16-0594 0 5 0 257 Male|*Iron|*Copper|Genome-Wide Association Study|*Homeostasis|Oxidoreductases|Membrane Proteins|Obesity|Inflammation 89 STEAP4 28561022 Nat Commun 2017 PMC5460031 10.1038/ncomms15508 0 74 0 257 Animals|Mice|IL17A protein, human|*Interleukin-17|*Oligodendrocyte Precursor Cells|Th17 Cells|Encephalomyelitis, Autoimmune, Experimental|Receptors, Interleukin-17|Signal Transduction|Cell Differentiation|*Gene Expression|Receptor, Notch1|Mice, Inbred C57BL|Interferon-gamma|Cell Proliferation 89 STK17B 28249207 Eur J Med Chem 2017 10.1016/j.ejmech.2017.02.048 0 0 0 215 *Apoptosis|Serine Threonine Kinase|Apoptosis Regulatory Proteins|benzofuran|*Benzofurans|*Islet Cells|*Protective Agents|Signal Transduction 32 STK33 29237806 Mol. Cancer Ther. 2017 10.1158/1535-7163.MCT-17-0324 5 1 0 144 Humans|Brachyury protein|*Chordoma|*Afatinib|*Fetal Proteins|*T-Box Domain Proteins|ErbB Receptors|Quinazolines|Cell Line, Tumor|Protein Kinase Inhibitors|Cell Proliferation|Bone Neoplasms|Gene Expression Regulation, Neoplastic|Signal Transduction|EGFR protein, human 48 STK33 29155043 Dev. Biol. 2017 10.1016/j.ydbio.2017.11.007 4 0 0 144 Male|Mice|Animals|*Spermatids|*Spermiogenesis|Spermatozoa|Testis|Spermatocytes|*Serine Threonine Kinase|Microtubules|Cytoskeleton|Mice, Knockout|Cell Differentiation|Fertility 48 STK33 29100402 Oncotarget 2017 PMC5652794 10.18632/oncotarget.20535 4 19 0 144 Humans|*Vascular Endothelial Growth Factor A|*HSP90 Heat-Shock Proteins|*Signal Transduction|Neovascularization, Pathologic|*Hypoxia-Inducible Factor 1|Proto-Oncogene Proteins c-akt|Angiogenesis Inhibitors|Cell Hypoxia|Cell Line, Tumor|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Apoptosis|*Hypoxia|Gene Expression Regulation, Neoplastic|STK33 protein, human|Protein-Serine-Threonine Kinases 48 STK33 29085482 Oncol Lett 2017 PMC5649584 10.3892/ol.2017.6766 3 3 0 144 Humans|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Prognosis|Carcinoma, Large Cell|Squamous Cell Carcinoma|Adenocarcinoma|Immunohistochemistry|Biomarkers, Tumor|*Protein-Serine-Threonine Kinases|Lung|Small Cell Lung Carcinoma|Lung Adenocarcinoma|Survival Analysis|Survival Rate|mRNA|China|STK33 protein, human 48 STK40 28419554 Exp. Dermatol. 2017 10.1111/exd.13355 11 0 0 141 Mice|Animals|*Keratinocytes|LATS2 protein, human|*Protein-Serine-Threonine Kinases|*Tumor Suppressor Proteins|Mirn31 microRNA, mouse|MicroRNAs|Signal Transduction|Apoptosis|Cell Proliferation|Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Differentiation|3' Untranslated Regions|*Genes, Regulator|Cell Line, Tumor|Hair Follicle|Stk40 protein, mouse 24 STK40 28358362 Cell Death Dis 2017 PMC5386544 10.1038/cddis.2017.148 3 17 0 141 Mice|Animals|*Erythropoiesis|Erythroblasts|Cell Differentiation|Anemia|Cell Proliferation|Embryo, Mammalian|Serine Threonine Kinase|Fetus|Apoptosis|Liver|Erythrocytes|Stk40 protein, mouse 24 STK40 28089446 Structure 2017 PMC5299031 10.1016/j.str.2016.12.008 8 10 0 141 Intracellular Signaling Peptides and Proteins|Protein-Serine-Threonine Kinases|Protein Binding|Binding Sites|Ubiquitin-Protein Ligases|Substrate Specificity|Amino Acid Sequence|Crystallography, X-Ray|Models, Molecular 24 STK40 28085489 DNA Cell Biol. 2017 10.1089/dna.2016.3517 7 6 0 141 Humans|*JNK Mitogen-Activated Protein Kinases|*Keratinocytes|*Apoptosis|Downregulation|Upregulation|MicroRNAs|*Psoriasis|NF-kappa B|Viability, Cell|Signal Transduction|RNA, Small Interfering|Cell Movement|3' Untranslated Regions|MAPK, p38|MAP Kinase Signaling System|SOX9 protein, human|SOX9 Transcription Factor|STK40 protein, human 24 STYX 29250526 Front Mol Biosci 2017 PMC5715325 10.3389/fmolb.2017.00076 2 18 0 164 Humans|Rats|Animals|*PC12 Cells|*Neurons|Neurites|Apoptosis Regulatory Proteins|HeLa Cells|Protein Binding|*Phenotype|STYX protein, human|Nuclear Proteins|Intracellular Signaling Peptides and Proteins 64 STYX 28783707 Sci Immunol 2017 10.1126/sciimmunol.aao2062 0 0 0 164 Humans|Aged|*Pluto|Apoptosis Regulatory Proteins|HeLa Cells|STYX protein, human|Nuclear Proteins|Intracellular Signaling Peptides and Proteins 64 STYX 28601579 Waste Manag 2017 10.1016/j.wasman.2017.05.049 0 0 0 164 *Sewage|*Pyrolysis|Incineration|Waste Disposal, Fluid|Phosphorus|Waste Water|Nitrogen|Coal|Gases|Power Plants|Filtration|Temperatures|*Technology|*Bone Screws|Germany 64 STYX 28408485 Biochem. Soc. Trans. 2017 10.1042/BST20160279 2 0 0 164 Phylogeny|FBXW7 protein, human|F-Box-WD Repeat-Containing Protein 7|F-Box Proteins|Intracellular Signaling Peptides and Proteins|Cell Cycle Proteins|Nuclear Proteins|Ubiquitylation|Mitogen-Activated Protein Kinases|Cell Nucleus|Ubiquitin-Protein Ligases|Protein Tyrosine Phosphatase|MAP Kinase Signaling System|Protein Binding|Cytosol 64 STYX 28408478 Biochem. Soc. Trans. 2017 10.1042/BST20160273 3 0 0 164 Phosphatases, MAPK|Mitogen-Activated Protein Kinases|*Neurite Outgrowth|Apoptosis Regulatory Proteins|Binding Protein|MAP Kinase Signaling System|Signal Transduction|Neurites|Protein Transport|Protein Binding 64 STYX 28196911 Sci Signal 2017 10.1126/scisignal.aam9607 0 1 0 164 Ubiquitin-Protein Ligases|Ubiquitin|FBXW7 protein, human|F-Box-WD Repeat-Containing Protein 7 64 SVOP 28900577 Transl Vis Sci Technol 2017 PMC5588911 10.1167/tvst.6.5.4 5 0 0 115 Humans|*Visual Field Tests|*Visual Fields|*Vision Disorders|*Glaucoma|*Saccades|*Tetrahymenina|Algorithms 26 SVOP 28900576 Transl Vis Sci Technol 2017 PMC5588909 10.1167/tvst.6.5.3 3 0 0 115 Animals|*Visual Field Tests|*Glaucoma|Visual Fields|*Saccades|Vision Disorders|*Tetrahymenina|Algorithms|*Disease Vectors 26 SVOP 28878041 Open Biol 2017 PMC5627054 10.1098/rsob.170142 5 1 0 115 Humans|Phylogeny|*Biological Evolution|MFSD8 protein, human|Membrane Transport Proteins|Evolution, Molecular|Biological Transport|*Neurons|Bioinformatic|*Heterozygote 26 SWAP70 28865029 Adv. Exp. Med. Biol. 2017 10.1007/978-4-431-56550-5_19 0 1 0 162 Humans|Mice|Animals|drebrins|Neuropeptides|Lamellipodia|Actin Cytoskeleton|Actin|Cell Migration|drebrin E|Tropomyosin|Nuclear Proteins|Guanine Nucleotide Exchange Factors|DNA-Binding Proteins|Fibroblasts|Transfections|Minor Histocompatibility Antigens 81 SWAP70 28780965 Cell. Immunol. 2017 PMC5877469 10.1016/j.cellimm.2017.05.010 3 11 0 162 Humans|Mice|Animals|*Autoimmunity|*CD11c Antigen|B Cells|Subset, B-Cell|T-Box Domain Proteins|DNA-Binding Proteins|Nuclear Proteins|Minor Histocompatibility Antigens|Guanine Nucleotide Exchange Factors|Cell Differentiation|ITGAM protein, human|CD11b Antigen 81 SWAP70 28489960 Small GTPases 2017 PMC6548301 10.1080/21541248.2017.1328302 1 4 0 162 Humans|Mice|Animals|*Actins|*Phagosomes|Filaments, Actin|Guanine Nucleotide Exchange Factors|Nuclear Proteins|DNA-Binding Proteins|Microfilament Proteins|Phagocytosis|rac1 GTP-Binding Protein|Minor Histocompatibility Antigens|rho GTPases|Polymerization|siRNA|*Oligonucleotides|Macrophages|Synapses|SWAP70 protein, human|Swap70 protein, mouse 81 SWAP70 28468968 J. Immunol. 2017 10.4049/jimmunol.1601928 1 2 0 162 *Lipidomics|*CD11c Antigen|Nuclear Proteins|Guanine Nucleotide Exchange Factors|DNA-Binding Proteins|Minor Histocompatibility Antigens|Dendritic Cells|Tolerogen|*Organic Chemicals 81 TARBP1 28063705 Vaccine 2017 10.1016/j.vaccine.2016.12.054 4 4 0 41 Animals|Mice|*Influenza A Virus, H9N2 Subtype|*Influenza in Birds|*Downregulation|Dendritic Cells|MicroRNAs|Cytokines|Virus Replication|Signal Transduction|TNF protein, human|Tumor Necrosis Factor-alpha|Up-Regulation 26 TBX22 28877219 PLoS ONE 2017 PMC5587310 10.1371/journal.pone.0183772 6 1 0 28 Male|Humans|Female|*Cleft Lip|*Cleft Palate|*Asian|Genome-Wide Association Study|*Genes, X-Linked|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|European Continental Ancestry Group|Mouth Abnormalities|Triad resin|*Acrylic Resins|Chromosomes 52 TBX22 28582446 PLoS ONE 2017 PMC5459506 10.1371/journal.pone.0179078 1 2 0 28 Humans|Mice|Animals|*Palate|Cleft Palate|Mesenchyme|Homeodomain Proteins|Transcription Factors|Embryo, Mammalian|Gene Expression Regulation, Developmental|Morphogenesis|Cell Proliferation|Signal Transduction|*Cell Line 52 tbxt 28978482 Cell Rep 2017 PMC5679461 10.1016/j.celrep.2017.09.017 8 1 0 369 Animals|*Xenopus laevis|Xenopus Proteins|Mesoderm|Gastrula|Embryonic Induction|Body Patterning|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Transforming Growth Factor beta|*B-Lymphocytes|Cell Division 75 TDRD3 28698590 Sci Rep 2017 PMC5506013 10.1038/s41598-017-04955-4 0 13 0 132 Humans|*Tudor Domain|Neoplasm Invasiveness|*Tumorigenesis|*Cell Transformation, Neoplastic|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Cell Line, Tumor|Proteins|RNA, Small Interfering|Neoplasm Transplantation|Lung Neoplasms 25 TDRD3 28534707 RNA Biol 2017 PMC5546716 10.1080/15476286.2017.1330741 5 0 0 132 Animals|*RNA|DNA Topoisomerases, Type I|Tudor Domain|*DNA|mRNA|Protein Binding|DNA, Single-Stranded|Histones|Binding Proteins|*Isomerases 25 TDRD3 28298358 Am. 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Renal Physiol. 2017 PMC5538839 10.1152/ajprenal.00054.2017 5 4 0 132 Rats|Animals|*Catenin Proteins|Aquaporin 2|AVP protein, human|Vasopressin|Kidney Tubules, Collecting|Chromatography, Liquid|Tandem Mass Spectrometry|Kidney Medulla|Phosphorylation|*Cell Nucleus|Proteomics|Kidney|Computational Biology|Neurophysins 25 TDRD3 28176834 Sci Rep 2017 PMC5296760 10.1038/srep42123 2 12 0 132 *DNA Topoisomerases, Type I|Binding Sites|Protein Binding|Gene Expression|*Isomerases|Amino Acid Sequence|Crystallography, X-Ray|RNA|Cloning, Molecular|Catalytic Domain|Protein Interaction Domains and Motifs|Proteins|Models, Molecular|DNA 25 TDRD3 28101374 Cell Discov 2017 PMC5206711 10.1038/celldisc.2016.48 4 49 0 132 *Methylation|*Arginine|Tudor Domain|Amino Acid Sequence|*Protein Processing, Post-Translational|Protein Binding|Histones|Protein Motifs 25 TENM3 29207951 BMC Neurosci 2017 PMC5718065 10.1186/s12868-017-0397-5 7 17 0 39 Animals|Mice|*Visual Pathways|Geniculate Bodies|Retina|Superior Colliculi|Axons|Retinal Ganglion Cells|Nerve Tissue Proteins|Membrane Proteins|Functional Laterality|Mice, Knockout|*Signal Transduction|Brain|Animals, Newborn 28 TENM3 28317148 Hematol Oncol 2017 10.1002/hon.2391 4 1 0 39 Humans|*Bortezomib|*Multiple Myeloma|*Genome-Wide Association Study|*Peripheral Neuropathy|Proteasome Inhibitor|Boronic Acids|Antineoplastic Agents|Pyrazines|Single Nucleotide Polymorphisms|Risk Factors|Nervous System 28 TESC 29284304 Hum. Gene Ther. 2017 10.1089/hum.2017.064 10 0 0 122 Humans|*RNA, Long Noncoding|*Transcriptome|*Brain Ischemia|*Stroke|mRNA|MicroRNAs|Sequencing, RNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Bioinformatics|Biomarkers, Tumor|Downregulation|Upregulation 66 TESC 28575645 J Psychiatr Res 2017 10.1016/j.jpsychires.2017.05.010 2 2 0 122 Humans|*White Matter|*Depressive Disorder, Major|Diffusion Tensor Imaging|Genome-Wide Association Study|*Hippocampus|Brain|Imaging, Magnetic Resonance|DNA Methylation|Genotype|*Nerve Net|Polymorphism, Single Nucleotide 66 TESC 28556291 Environ. Mol. Mutagen. 2017 PMC6488305 10.1002/em.22095 21 1 0 122 Male|Infant, Newborn|Humans|Female|Pregnancy|phthalic acid|*DNA Methylation|*Fetal Blood|*Phthalic Acids|Maternal Exposure|Endocrine Disruptors|Prenatal Exposure Delayed Effects|Exposures, Environmental|LASP1 protein, human|Cytoskeletal Proteins|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 66 TESC 28515276 J. Cell Biol. 2017 PMC5461031 10.1083/jcb.201701165 12 46 0 122 *Ribonucleoprotein, U5 Small Nuclear|*Spliceosomes|Ribonucleoprotein, U4-U6 Small Nuclear|RNA Splicing|Small Nuclear Ribonucleoprotein Particle|RNA Precursors|Saccharomyces cerevisiae Proteins|*Molecular Chaperones|*HSP90 Heat-Shock Proteins|Retinitis Pigmentosa 66 TESC 28335611 Can. J. Microbiol. 2017 10.1139/cjm-2016-0458 2 0 0 122 *Fatty Acids, Nonesterified|Escherichia coli|*Acinetobacter|Acinetobacter baylyi|Metabolic Engineering|Escherichia coli Proteins|Fatty Acids|Thiolester Hydrolases|Biofuel|CoA, Acyl|Esters|Plasmid 66 TESC 28084108 Arch. Physiol. Biochem. 2017 10.1080/13813455.2016.1275701 0 1 0 122 Rats|Animals|*Altitude|B-insulin|*Insulin|MTOR protein, human|TOR Serine-Threonine Kinases|*Signal Transduction|*Insulin, Regular, Human|Gluconeogenesis|*Livers|Phosphorylation|Insulin Receptor Substrate Proteins|Insulin Resistance|Proto-Oncogene Proteins c-akt|AMP-Activated Protein Kinases|*Biotin 66 TESC 28076433 PLoS ONE 2017 PMC5226788 10.1371/journal.pone.0170036 1 27 0 122 *Muscle, Smooth, Vascular|*Myocytes, Smooth Muscle|MTOR protein, human|*TOR Serine-Threonine Kinases|Platelet Derived Growth Factor B|Becaplermin|Signal Transduction|Cell Proliferation|Cells, Cultured|Aorta 66 TEX14 28295819 Genes Chromosomes Cancer 2017 PMC5612339 10.1002/gcc.22457 7 3 0 73 Adult|Adolescent|Male|Humans|Child|Infant, Newborn|Infant|Child, Preschool|Young Adult|Genome-Wide Association Study|Testicular Germ Cell Tumor|*Tumors, Germ Cell|Testicular Neoplasms|SNPs|Genetic Predisposition to Disease|Stem Cell Factor|Alleles|Genotype|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|bcl-2 Homologous Antagonist-Killer Protein|Case-Control Studies|GAB2 protein, human|Adaptor Proteins, Signal Transducing|BAK1 protein, human 43 TEX14 28206990 Genet. Med. 2017 10.1038/gim.2016.225 15 0 0 73 Male|Humans|*Azoospermia|Spermatogenesis|Whole Exome Sequencing|Homozygote|Testis|Pedigree|Sperm|Mutation 43 TEX14 28088409 J. Dairy Sci. 2017 10.3168/jds.2016-11910 11 1 0 73 Cattle|Female|Animals|*Genome-Wide Association Study|Canada|*Lactation|Milk|Linkage Disequilibrium|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Phenotype|Breeding|Genotype|Chromosomes|Model, Linear 43 TEX19 29194616 J. Cell. Physiol. 2017 10.1002/jcp.26303 5 0 0 48 Male|Mice|Animals|*RNA|*Mesenchymal Stem Cells|*Spermatogonia|*Sequencing, RNA|Adult Germline Stem Cells|Spermatogenesis|Testis|Single-Cell Analysis|Genes, Homeobox|*Whole Exome Sequencing|Gene Expression Profiling|Cell Differentiation|Gene Expression Regulation, Developmental|Stem Cell Self-Renewal|Protein Interaction Maps|TAF7L protein, mouse|Transcription Factor TFIID|TATA-Binding Protein Associated Factors 20 TEX19 28806172 Elife 2017 PMC5570191 10.7554/eLife.26152 11 35 0 48 Humans|Animals|*Retroelements|*Long Interspersed Nucleotide Elements|DNA Methylation|RNA-Binding Proteins|Nuclear Proteins|E3 Ubiquitin Ligase|Recombination, Genetic|Mammals|Tex19 protein, human 20 TEX19 28708824 PLoS Genet. 2017 PMC5533463 10.1371/journal.pgen.1006904 8 18 0 48 Male|Mice|Animals|*Spermatocytes|meiotic recombination protein SPO11|*Endodeoxyribonucleases|Synapsis, Chromosomal|Meiosis|Meiotic Prophase I|DNA Breaks, Double-Stranded|histone H3 trimethyl Lys4|Histones|Chromosomes|Cell Cycle Proteins|*Homologous Recombination|Esterases|Tex19 protein, mouse|Nuclear Proteins 20 TEX19 28604758 Pediatr. Res. 2017 10.1038/pr.2017.137 0 0 0 48 Rats|Animals|Female|Pregnancy|*DNA Methylation|*Fetal Growth Retardation|syncytin|*Rats, Wistar|*Pregnancy Proteins|*Gene Products, env|Placenta|Epigenesis, Genetic|Promoter Regions, Genetic|Nicotine|Gene Expression Regulation, Developmental 20 TEX19 28446200 Mol. Cancer 2017 PMC5406905 10.1186/s12943-017-0653-4 6 10 0 48 Male|Humans|*Cell Proliferation|Cancer Biomarkers|Gene Expression Regulation, Neoplastic|Testis|RNA-Binding Proteins|Nuclear Proteins|Cell Line, Tumor|*B-Lymphocytes|Xenograft Model Antitumor Assays|Oncogenesis|Prognosis|Stem Cells|Tex19 protein, human 20 TEX19 28254886 J. Cell. Sci. 2017 10.1242/jcs.188763 4 1 0 48 20 Tfcp2l1 28982712 J. Cell. Sci. 2017 10.1242/jcs.206532 3 1 0 100 Mice|Animals|Mouse Embryonic Stem Cells|Cell Differentiation|Cell Lineage|Repressor Proteins|Transcription Factor|Wnt Signaling Pathway|Gene Expression Regulation, Developmental 46 Tfcp2l1 28577314 Elife 2017 PMC5484618 10.7554/eLife.24265 13 36 0 100 Mice|Animals|Kidney Tubules, Collecting|Aquaporin 2|Kidneys|Epithelial Cell|Transcription Factor|Nephron|Signal Transduction|*Complement Factor B|3'-(1-butylphosphoryl)adenosine 46 TFEC 29148086 Histopathology 2017 10.1111/his.13439 5 1 0 72 Humans|*Carcinoma, Renal Cell|MITF protein, human|*Microphthalmia-Associated Transcription Factor|Kidney Neoplasms|*Gene Fusion|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Translocation, Genetic|Chromosomes, Human, X|*Sequencing, RNA|Oncogene Proteins, Fusion|In Situ Hybridization, Fluorescence|*Base Sequence|*Whole Exome Sequencing|PRCC protein, human|Neoplasm Proteins|Cell Cycle Proteins 93 TFEC 28851811 Mol. Cancer Res. 2017 10.1158/1541-7786.MCR-17-0320 14 1 0 72 MITF protein, human|*Microphthalmia-Associated Transcription Factor|*Organelle|Lysosomes|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|*Signal Transduction|mTORC1|Autophagy|Oncogenesis|Genes, Tumor Suppressor|Energy Metabolism|Cancer|*Acclimatization|Polytetrafluoroethylene 93 TFEC 28556369 Dev. Dyn. 2017 10.1002/dvdy.24525 5 0 0 72 Animals|*Retinal Pigment Epithelium|*Retina|Morphogenesis|Zebrafish|Gene Expression Regulation, Developmental|Cell Differentiation|Organogenesis|Signal Transduction|Cells, Epithelial 93 TFEC 28407117 Nucleic Acids Res. 2017 PMC5570195 10.1093/nar/gkx276 11 0 0 72 *Neural Networks, Computer|Amino Acid Sequence|*Ligands|Sequence Alignment|Protein Binding|Peptides|Algorithm 93 TFEC 28238747 J. Allergy Clin. Immunol. 2017 10.1016/j.jaci.2017.01.024 18 7 0 72 *Endoplasmic Reticulum Stress|*STAT6 Transcription Factor|*Interleukin-4|*Receptor, IL4|DDIT3 protein, human|*Homologous Protein, C-EBP|*Signal Transduction|*Macrophages|*Asthma|Cells, Cultured 93 TFEC 28074186 Biomed Res Int 2017 PMC5198153 10.1155/2016/4780872 2 24 0 72 Animals|Acetaminophen|Chemical and Drug Induced Liver Injury|Hepatocytes|Liver|Cells, Cultured|Disease Models, Animal|*Drug-Related Side Effects and Adverse Reactions 93 TFEC 29604926 Crit Rev Oncog 2017 10.1615/CritRevOncog.2017020558 1 0 0 72 Humans|*Carcinoma, Renal Cell|Neoplasm, Renal|*Prognosis|Translocation, Genetic|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|PEComa|Alveolar Soft Part Sarcoma|Chromosomes, Human, X|Gene Fusion|Immunohistochemistry|MITF protein, human|Microphthalmia-Associated Transcription Factor|In Situ Hybridization, Fluorescence|Oncogene Proteins, Fusion|Gene Rearrangement|Biomarkers, Tumor|Melanoma 93 TICRR 28877985 Mol. Biol. Cell 2017 PMC5662258 10.1091/mbc.E17-07-0448 7 20 0 110 *DNA Replication|Cell Cycle Proteins|DNA-Binding Proteins|Nuclear Proteins|S Phase|Carrier Proteins|Xenopus Proteins|Saccharomyces cerevisiae Proteins|Cyclin-Dependent Kinases|DNA Helicases|Chromatin|Phosphorylation|DNA 29 TICRR 28785014 Nat Commun 2017 PMC5547116 10.1038/s41467-017-00339-4 13 38 0 110 Humans|*S Phase|Mitosis|Protein Phosphatase 2|Phosphorylation|CDC2 Protein Kinase|Protein-Serine-Threonine Kinases|Microtubule-Associated Proteins 29 TICRR 28739856 Mol. Cell. Biol. 2017 PMC5615187 10.1128/MCB.00344-17 1 7 0 110 Humans|Animals|*Phosphorylation|Cell Cycle Proteins|Cyclin-Dependent Kinases|CDK2 protein, human|Cyclin-Dependent Kinase 2|CDC2-CDC28 Kinases|DNA Replication|Carrier Proteins|DNA-Binding Proteins|S Phase|Nuclear Proteins|Protein Kinases|TYRP1 protein, human|*Membrane Glycoproteins|DNA Damage 29 TICRR 28521375 Int J Sports Med 2017 10.1055/s-0043-106190 2 0 0 110 Genome-Wide Association Study|Shoulder Dislocations|Football|Genetic Loci|Polymorphism, Single Nucleotide 29 TICRR 28439015 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5441733 10.1073/pnas.1619832114 11 8 0 110 *Tumor Suppressor Protein p53|Cell Cycle Proteins|Nuclear Proteins|DNA-Binding Proteins|Carrier Proteins|Phosphorylation|DNA Replication|Ataxia Telangiectasia Mutated Proteins|CDK2 protein, human|Cyclin-Dependent Kinase 2|Checkpoint Kinase 1|Protein Kinases|DNA Damage|RNA Interference|*Cell Cycle Checkpoints|DNA 29 TICRR 28118095 OMICS 2017 10.1089/omi.2016.0157 0 1 0 110 Humans|*Saccharomyces cerevisiae|DNA Replication|Saccharomyces cerevisiae Proteins|Cell Cycle Proteins|Binding Protein|DNA-Binding Proteins|*Yeast, Dried|Nuclear Proteins|DNA Damage|Protein-Serine-Threonine Kinases|Cell Cycle|Cell Division|*Aging|*Cancer|MTBP protein, human|TICRR protein, human 29 TIMD4 29233585 J. Neuroimmunol. 2017 10.1016/j.jneuroim.2017.11.017 2 0 0 299 Humans|*Stroke|*Brain Ischemia|Monocytes|Hepatitis A Virus Cellular Receptor 2|Macrophages|Up-Regulation|Membrane Proteins|Tumor Necrosis Factor-alpha|T-Lymphocytes 81 TIMD4 29227551 Curr Protoc Cell Biol 2017 10.1002/cpcb.32 5 1 0 299 *Extracellular Vesicles|Exosomes|Serine, Phosphatidyl|Cell-Derived Microparticles|Flow Cytometry 81 TIMD4 29208769 Biosci. Rep. 2017 PMC5773822 10.1042/BSR20171058 7 5 0 299 Cholesterol, HDL|Cholesterol, LDL|Coronary Disease|Genetic Predisposition to Disease|Triglycerides|Polymorphism, Single Nucleotide|Stroke|Genotype|Risk Factors|Lipids 81 TIMD4 28949386 Int. J. Mol. Med. 2017 PMC5627870 10.3892/ijmm.2017.3150 2 27 0 299 Mice|Animals|*Sirtuin 1|Th2 Cells|*Inflammation|Allergic Rhinitis|Dendritic Cells|Membrane Proteins|FASLG protein, human|Fas Ligand|Cell Differentiation|Lymphocyte Activation|Hepatitis A Virus Cellular Receptor 1|Cell Proliferation|Sirt1 protein, mouse 81 TIMD4 28751473 J. Leukoc. Biol. 2017 10.1189/jlb.1A0417-150RR 6 0 0 299 Animals|Mice|*Macrophage|*Promoter Regions, Genetic|Receptor, CSF 1|*Embryo, Mammalian|Organogenesis|Sac, Yolk|Gene Expression Regulation, Developmental|Transcriptome|Gene Expression Profiling|Transcription Factors|Genomics|Cell Differentiation 81 TIMD4 28740388 Int J Nanomedicine 2017 PMC5505621 10.2147/IJN.S132762 11 3 0 299 Female|Humans|*HIV-1|*Exosomes|HAVCR1 protein, human|*Hepatitis A Virus Cellular Receptor 1|Virus Entry|phosphatidylserine receptor|Receptors, Cell Surface|Receptors, Virus|*Macrophages|ARHGEF5 protein, human|*Rho Guanine Nucleotide Exchange Factors|Serine, Phosphatidyl|Host-Pathogen Interactions|Clathrin|*HIV Seropositivity|Breast Milk 81 TIPARP 29274782 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.12.113 4 2 0 455 AHR protein, human|*Receptors, Aryl Hydrocarbon|*RNA, Long Noncoding|*Basic Helix-Loop-Helix Transcription Factors|Tetrachlorodibenzo-p-dioxin|Poly ADP Ribose Polymerase|Mono-ADP-Ribosylation|Mono-ADP-Ribosyltransferase|Signal Transduction|Gene Expression Regulation 59 TIPARP 29180230 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.11.020 16 0 0 455 *Glucocorticoids|Corticosterone|Receptors, Glucocorticoid|DUSP1 protein, human|Dual Specificity Phosphatase 1|Cortisol|CXXC5 protein, human|Carrier Proteins|Transcriptomes|Transcription Factors|Signal Transduction|Up-Regulation|*Nervous System Physiological Phenomena|mRNA|Brain 59 TIPARP 28860561 Sci Rep 2017 PMC5579248 10.1038/s41598-017-10824-x 12 61 0 455 Mice|Humans|Animals|*Caco-2 Cells|AHR protein, human|Aryl Hydrocarbon Receptor|CYP1A1 protein, human|CYP1A1|Basic Helix-Loop-Helix Transcription Factors|Tetrachlorodibenzo-p-dioxin|CYP1B1 protein, human|Cytochrome P-450 CYP1B1|*Short-Chain Fatty Acids|Poly ADP Ribose Polymerase|*Colon Cancer|Butyrate|Histone Deacetylase Inhibitors|Acetylation|*Hydrocarbons 59 tiprl 29273778 Nat Commun 2017 PMC5741625 10.1038/s41467-017-02405-3 3 23 0 1859 *Protein Phosphatase 2A|*Methylation|Holoenzymes|Subunits, Catalytic|Intracellular Signaling Peptides and Proteins|Protein Folding|Molecular Chaperones|Signal Transduction|Models, Molecular|*Biochemical Phenomena|*Protein Processing, Post-Translational 34 tiprl 28792098 J. 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Med. 2017 PMC5336561 10.1038/emm.2016.152 16 127 0 1859 *Cyclic AMP|*Proto-Oncogene Proteins c-akt|Carcinoma, Non-Small-Cell Lung|*Lung Cancer|RAP1A protein, human|*rap1 GTP-Binding Proteins|*Signal Transduction|Protein Kinase A|HDAC8 protein, human|*Histone Deacetylases|*Repressor Proteins|Guanine Nucleotide Exchange Factors|Phosphorylation|Proteasome|Apoptosis|JNK Pathway|Isoproterenol|Cell Line, Tumor 34 TM4SF5 29137358 Oncotarget 2017 PMC5663530 10.18632/oncotarget.17644 0 34 0 210 *Cues|Hepatocellular Carcinoma|Liver Neoplasms|*Extracellular Matrix|Cell Movement|Cell Line, Tumor|Membrane Proteins|Hepatocytes|Signal Transduction|*Gels 57 TM4SF5 28458469 Mediators Inflamm. 2017 PMC5385246 10.1155/2017/5108525 0 28 0 210 Epithelial-Mesenchymal Transition|Cell Movement|ErbB Receptors|Cell Proliferation|Cell Line, Tumor|Hepatocytes|Membrane Proteins|Signal Transduction|*Phenotypes|Chalcone|Tetraspanins|Integrins 57 TM4SF5 28255353 Theranostics 2017 PMC5327636 10.7150/thno.15629 3 59 0 210 Humans|Mice|Animals|Hepatocellular Carcinoma|Liver Neoplasms|*Apoptosis|Cell Movement|Cell Line, Tumor|Antibodies, Monoclonal|Cell Proliferation|Xenograft Model Antitumor Assays|Membrane Proteins|IgG1|Single-Chain Variable Fragment|TM4SF5 protein, human 57 TM4SF5 28129652 Oncotarget 2017 PMC5355095 10.18632/oncotarget.14809 1 15 0 210 Carcinoma, Hepatocellular|Liver Neoplasms|Cell Proliferation|Cell Movement|Membrane Proteins|Cell Line, Tumor|Signal Transduction|Colon Cancer 57 TM4SF5 28073834 FASEB J. 2017 10.1096/fj.201600944RR 8 1 0 210 Cell Movement|Signal Transduction|ErbB Receptors|Liver Neoplasms|TSPAN32 protein, human|Tetraspanins|Epithelial-Mesenchymal Transition|Membrane Proteins|Membrane Microdomains|Cell Line, Tumor 57 TMC2 29093662 Front Mol Neurosci 2017 PMC5651230 10.3389/fnmol.2017.00326 13 4 0 41 Mice|Animals|*Hair Cells, Auditory, Outer|Mechanotransduction, Cellular|Hair Cells, Auditory, Inner|Hair Cells, Vestibular|Membrane Proteins|Patch-Clamp Techniques|Animals, Newborn|Calcium|TMC2 protein, mouse 53 TMC8 29212247 Oncotarget 2017 PMC5706893 10.18632/oncotarget.21786 9 5 0 65 Humans|Female|Male|*Squamous Cell Carcinoma of Head and Neck|*mRNA|*Prognosis|Human Papilloma Virus|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Papillomavirus Infections|Biomarkers, Tumor|Kaplan-Meier Analysis|Transcriptome|Receiver Operating Characteristic|TMC8 protein, human|Membrane Proteins|FRMD5 protein, human|Tumor Suppressor Proteins 50 TMC8 29170429 Sci Rep 2017 PMC5701039 10.1038/s41598-017-16493-0 9 3 0 65 Humans|Japan|Genome-Wide Association Study|Glycated Hemoglobin A|Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|European Continental Ancestry Group|Diabetes Mellitus, Type 2|TMC6 protein, human|Membrane Proteins|TMC8 protein, human|SIX2 protein, human|Nerve Tissue Proteins|Homeodomain Proteins 50 TMC8 28781795 Mol Clin Oncol 2017 PMC5532682 10.3892/mco.2017.1285 1 0 0 65 Humans|*Carcinoma, Hepatocellular|*Liver Cancer|Immunohistochemistry|Prognosis|Biomarkers, Tumor|Kaplan-Meier Estimate|Proportional Hazard Model|Upregulation|Real-Time Polymerase Chain Reaction|Blotting, Western|TMC8 protein, human|Membrane Proteins 50 TMC8 28646613 J Eur Acad Dermatol Venereol 2017 10.1111/jdv.14431 4 0 0 65 Humans|*Epidermodysplasia Verruciformis|*Papillomavirus Infections|Papillomaviridae|*Mutations|Membrane Proteins|TMC8 protein, human 50 TMC8 28196644 J. 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Dermatol. 2017 10.1016/j.jaad.2016.12.035 7 0 0 65 Humans|*Epidermodysplasia Verruciformis|Papillomaviridae|Human Papillomavirus Infections|Homozygote|Mutations|Genetic Predisposition to Disease|Membrane Proteins|Immunocompromised Hosts|Skin Diseases|TMC8 protein, human 50 tmco1 29281821 Cell Rep 2017 PMC5868721 10.1016/j.celrep.2017.12.006 19 6 0 185 Humans|*Eukaryotic Cells|*Eukaryotes|Phylogeny|*Endoplasmic Reticulum|Mitochondrial Proteins|Membrane Protein|Electron Transport Complex IV|Mitochondrial Membranes|Membrane Transport Proteins|Ribosomes|Saccharomyces cerevisiae Proteins|Mitochondria|Nuclear Proteins|Escherichia coli Proteins|Bacterial Proteins|Protein Biosynthesis 42 tmco1 29104244 Int J Mol Sci 2017 PMC5713272 10.3390/ijms18112302 1 3 0 185 Genome-Wide Association Study|Case-Control Studies|*Vitamin C|*Glaucoma, Primary Open Angle|Genetic Predisposition to Disease|*Locus, Genetic|Polymorphism, Single Nucleotide|Gene Frequency|Intraocular Pressure|Genotype|*Risk Factors|*Vitamins 42 tmco1 28972042 Clin. Cancer Res. 2017 10.1158/1078-0432.CCR-17-0002 3 4 0 185 42 tmco1 28472212 Invest. Ophthalmol. Vis. Sci. 2017 10.1167/iovs.16-20797 1 0 0 185 *Visual Fields|*Visual Field Tests|*Glaucoma|Glaucoma, Open-Angle|*Vision Disorders|Genetic Predisposition to Disease|Intraocular Pressure|Polymorphism, Single Nucleotide|Genotype|Cyclin-Dependent Kinase Inhibitor p15|Homeodomain Proteins|Trans-Activators|Nerve Fibers 42 TMEFF1 29228234 J Mol Cell Biol 2017 PMC6161409 10.1093/jmcb/mjx052 2 3 0 69 Humans|Male|*Cell Plasticity|PTEN protein, human|*PTEN Phosphohydrolase|TGFBR2 protein, human|TGFBR2|*Prostate Cancer|Prostate|Receptors, Transforming Growth Factor beta|Signal Transduction|Tumorigenesis|Transforming Growth Factor beta|Protein-Serine-Threonine Kinases|Gene Expression Regulation, Neoplastic|Epithelial Cell|Cell Transformation, Neoplastic|Mutations|Gene Deletion|Disease Progression 26 TMEFF1 28955770 Biochem Biophys Rep 2017 PMC5614697 10.1016/j.bbrep.2017.06.008 0 7 0 69 *Pentylenetetrazole|*Endoplasmic Reticulum|*Plasma Membrane|Excitatory Amino Acid Transporter 3|Carrier Proteins|Glutamate|Neurons|Biological Transport|Glutathione|Neurodegenerative Diseases|*Redox|GABA|*Translocation, Genetic 26 TMEFF1 28167222 Toxicol. Appl. Pharmacol. 2017 10.1016/j.taap.2017.02.001 0 0 0 69 Male|Humans|Rats|Animals|*Testis|*mRNA|*Rats, Wistar|*Sperm|Epididymis|Seminiferous Tubule|*Testicular Diseases|*Biomarkers|Organ Size|Cisplatin|Pharmaceutical Preparations 26 TMEM135 29230809 Ann. Hum. Genet. 2017 10.1111/ahg.12235 1 0 0 40 Humans|Young Adult|Adult|*Genetic Markers|Cross-Sectional Studies|*Bone Density|Calcaneus|Single Nucleotide Polymorphisms|Osteoporosis|*Ultrasonography|RSPO3 protein, human|Thrombospondins 20 TMEM135 28974197 BMC Med. Genet. 2017 PMC5627468 10.1186/s12881-017-0468-6 1 2 0 40 Osteoporosis|Bone Density|Calcaneus|Polymorphism, Single Nucleotide|Genotype|*Ultrasonography|Heel 20 TMEM135 28459452 Nat. Biotechnol. 2017 PMC5462845 10.1038/nbt.3843 21 4 0 40 Humans|Male|Mice|Animals|*CRISPR-Cas Systems|Genome Editing|Clustered Regularly Interspaced Short Palindromic Repeats|CRISPR-Associated Protein 9|RNA, Guide|Genes, Transgenic, Suicide|Genetic Therapy|Endonucleases|Thymidine Kinase|Nickase|*Genomics|Adenovirus|Herpesvirus 1, Human|Bacterial Proteins 20 TMEM163 28258026 Diabetes Res. Clin. Pract. 2017 10.1016/j.diabres.2017.02.013 1 0 0 9 Humans|*Diabetes Mellitus, Type 2|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Alleles|Genotype|Case-Control Studies|Logistic Models 22 TMEM163 28199205 Front Biosci (Landmark Ed) 2017 PMC5517152 10.2741/4546 2 12 0 9 *Zinc|*Lysosomes|Transient Receptor Potential Channels|Calcium 22 TMEM165 29042410 G3 (Bethesda) 2017 PMC5714488 10.1534/g3.117.300339 3 40 0 47 40 TMEM165 28323990 J. Clin. Endocrinol. Metab. 2017 PMC6283449 10.1210/jc.2016-3443 17 0 0 47 40 TMEM165 28270545 Biochem. J. 2017 PMC5595065 10.1042/BCJ20160910 11 16 0 47 40 TMEM38B 29150909 Mol Genet Genomic Med 2017 PMC5823677 10.1002/mgg3.331 6 3 0 37 Humans|*Osteogenesis Imperfecta|*Arabs|*Genetic Testing|Genes, Recessive|Homozygote|Collagen Type I|Phenotype|Mutation|Extracellular Matrix Proteins 25 TMEM38B 29077908 J. Clin. Endocrinol. Metab. 2017 10.1210/jc.2017-01860 2 0 0 37 Humans|Female|*Menarche|Genome-Wide Association Study|Sexual Maturation|*Genetic Loci|Receptors, FSH|Follicle Stimulating Hormone, beta Subunit|Follicle Stimulating Hormone|Genotype|Polymorphism, Single Nucleotide 25 TMEM38B 28725987 Osteoporos Int 2017 10.1007/s00198-017-4143-8 9 0 0 37 Humans|*Osteogenesis Imperfecta|*High-Throughput Nucleotide Sequencing|*Genotype-Phenotype Correlation|*Mutation|*Chinese|Phenotype|Collagen Type I|Genotype|Wnt1 Protein|*Cohort Studies|China 25 TMEM38B 28323974 J. Clin. Endocrinol. Metab. 2017 PMC5470761 10.1210/jc.2016-3766 0 0 0 37 *Osteogenesis Imperfecta|*Mutations|Collagen Type I|Bone Density 25 TMEM38B 28116328 Mol Genet Genomic Med 2017 PMC5241205 10.1002/mgg3.257 9 3 0 37 Humans|*Osteogenesis Imperfecta|*Diagnosis, Differential|Heterozygote|Mutations|Collagen Type I|Tacrolimus Binding Proteins 25 TMEM70 28903497 Toxicol. Sci. 2017 10.1093/toxsci/kfx131 1 2 0 63 Rats|Animals|*Down-Regulation|*Hepatocytes|*Carcinogenesis|Carcinogens|Liver Neoplasms, Experimental|Thioacetamide|Rats, Inbred F344|Liver|Cell Proliferation|Glutathione S-Transferase pi|Upregulation|Cell Transformation, Neoplastic|Mitochondria|Tmem70 protein, rat|Membrane Proteins 44 TMEM70 28526534 Clin. Chim. Acta 2017 10.1016/j.cca.2017.05.023 2 0 0 63 Humans|Infant, Newborn|*Carbamoyl-Phosphate Synthase I Deficiency Disease|3-Methylglutaconic Aciduria|Metabolism, Inborn Errors|Carbamoyl-Phosphate Synthase (Ammonia)|Urea Cycle Disorder|Hyperammonemia|Mutation|*Urogenital Abnormalities 44 TMEM70 28173120 Hum. Mol. Genet. 2017 10.1093/hmg/ddw295 3 1 0 63 Humans|Mice|Animals|*Mice, Knockout|Mitochondrial Proteins|Mitochondrial Proton-Translocating ATPases|Disease, Mitochondrial|Mitochondria|Inner Mitochondrial Membrane|Oxidative Phosphorylation|Membrane Proteins|Mutations|Heterozygote|Cardiomyopathy|Metabolism, Inborn Errors|*Nitric Oxide Synthase|Adenosine Triphosphate|TMEM70 protein, human 44 TNFAIP2 28922540 Mol Oncol 2017 PMC5709621 10.1002/1878-0261.12138 4 9 0 118 64 TNFAIP2 28416970 Clin Epigenetics 2017 PMC5391602 10.1186/s13148-017-0335-5 7 11 0 118 64 TNFAIP2 28393234 Oncol. Rep. 2017 10.3892/or.2017.5557 8 2 0 118 64 TNP1 28977892 Oncotarget 2017 PMC5617452 10.18632/oncotarget.18660 0 2 0 248 Humans|Male|*Infertility, Male|*Protamines|*Asian Continental Ancestry Group|Spermatozoa|Polymorphism, Single Nucleotide|Spermatogenesis 93 TNP1 28736154 Gene 2017 10.1016/j.gene.2017.07.041 0 2 0 248 Male|Animals|*Buffaloes|*Retinoic Acid|*Embryonic Stem Cells|*Cell Differentiation|Gametogenesis|*Bison|Meiosis|Oocyte|Spermatocyte|Octamer Transcription Factor-3|Cells, Cultured|Spermatozoa|Embryoid Bodies|Zona Pellucida 93 TNP2 28871057 Reproduction 2017 10.1530/REP-17-0169 1 0 0 42 Male|Mice|Animals|Spermatids|RNA-Binding Proteins|mRNA|Spermatogenesis|*RNA Splicing|RNA Stability|MicroRNAs|DEAD-box RNA Helicases|TYRP1 protein, human|*Membrane Glycoproteins|Cytoplasm|Trans-Activators|Gene Expression Regulation 118 TNP2 28743739 J. Cell. Sci. 2017 10.1242/jcs.204966 6 0 0 42 Male|Spermatids|Spermatogenesis|inositol hexakisphosphate kinase|Phosphotransferases (Phosphate Group Acceptor)|Testis|Protamines|1-diphosphoinositol pentakisphosphate|Inositol Phosphates|RNA, Messenger 118 TNP2 28497500 Andrologia 2017 10.1111/and.12814 1 0 0 42 Male|Rats|Animals|*Histones|*Rats, Sprague-Dawley|*Melatonin|*Leptin|*Protamines|*Spermatogenesis|Spermatozoa|Chromatin 118 TNP2 28166958 Theriogenology 2017 10.1016/j.theriogenology.2016.12.002 4 1 0 42 Male|Animals|*Haploidy|*Sperm|Spermatids|Oocytes|Spermatogenesis|Sperm Injections, Intracytoplasmic|Testis|Fertility|Cell Differentiation|Embryonic Development|spermatid transition proteins|Chromosomal Proteins, Non-Histone|Cells, Cultured|*Goat 118 TNPO3 28356354 J. Biol. Chem. 2017 PMC5465493 10.1074/jbc.M117.777029 4 2 0 229 p31 integrase protein, Human immunodeficiency virus 1|*HIV Integrase|transportin SR2|HIV Infections|*beta Karyopherins|HIV-1|Nuclear Import|HIV Proteins|Virus Replication|DNA, Viral|Protein Binding|Cell Nucleus|Molecular Model 81 TONSL 28325102 Crit. Rev. Biochem. Mol. Biol. 2017 10.1080/10409238.2017.1304355 22 1 0 109 DNA Replication|DNA Repair|Genome Instability|DNA Breaks, Double-Stranded|Homologous Recombination|DNA Damage|Rad51 Recombinase|Recombination Repair, Homologous|DNA-Binding Proteins|DNA|Protein Binding 28 TOR2A 29223158 Biochemistry Mosc. 2017 10.1134/S0006297917110098 1 1 0 254 Humans|NF-kappa B|Vascular Cell Adhesion Molecule-1|Human Umbilical Vein Endothelial Cells|Signal Transduction|Intercellular Adhesion Molecule-1|Anti-Inflammatory Agents|Tumor Necrosis Factor-alpha|Cytokines|Inflammation|Interleukin-6|Chemokine CCL2|Cell Adhesion|mRNA|Atherosclerosis|Cells, Cultured 64 TOR2A 28811505 Sci Rep 2017 PMC5557946 10.1038/s41598-017-08288-0 1 0 0 254 Humans|*Parasympathomimetics|Chromatography, Liquid|Tandem Mass Spectrometry|*Peptides|Intercellular Signaling Peptides and Proteins|*Plasma|Radioimmunoassay|ELISA|Parasympathetic Nervous System|Chromatography, High Pressure Liquid 64 TOR2A 28647373 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.06.126 6 4 0 254 Humans|Rats|Animals|*AMP-Activated Protein Kinases|CASP3 protein, human|Caspase 3|Human Umbilical Vein Endothelial Cells|Apoptosis|Signal Transduction|Phosphorylation|Diabetes Mellitus, Experimental|Diabetic Cardiomyopathy|shRNA|Glucose|Cell Death|Up-Regulation 64 TOR2A 28184918 Oncol. Rep. 2017 10.3892/or.2017.5429 2 6 0 254 Female|Humans|*Ovarian Cancer|Glycogen Synthase Kinase 3|*Carcinoma, Ovarian Epithelial|Cystadenocarcinoma, Serous|Adenocarcinoma, Clear Cell|Adenocarcinoma, Mucinous|Prognosis|Endometrial Neoplasms|Ovary|Cell Proliferation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Survival Rate|RNA, Messenger|Lymphatic Metastasis|Tumor Cells, Cultured|Immunoenzyme Techniques|Blotting, Western 64 TOR2A 28164579 Clin. Lab. 2017 10.7754/Clin.Lab.2016.160136 0 0 0 254 Humans|*ST Segment Elevation Myocardial Infarction|Atherosclerosis|Coronary Artery Disease|Intercellular Signaling Peptides and Proteins|Biomarkers|Case-Control Studies 64 tppp3 29209165 Front Mol Neurosci 2017 PMC5702462 10.3389/fnmol.2017.00375 3 5 0 109 Animals|*Zebrafish|*Axons|*Nerve Regeneration|RNA, Micro|Cell Proliferation|Signal Transduction 22 tppp3 28819371 J Cancer 2017 PMC5556637 10.7150/jca.18943 3 23 0 109 Humans|*Tubulin|*Polymerization|*Cell Proliferation|*Colorectal Cancer|Apoptosis|Cell Movement|*Colonic Neoplasms|Cell Line, Tumor|mRNA|Immunohistochemistry|Proteins 22 tppp3 28784648 Hypertension 2017 PMC5997260 10.1161/HYPERTENSIONAHA.117.09458 8 1 0 109 Humans|*Blood Pressure|*Transcriptome|*Blood Pressure Determination|Hypertension|*Transcriptome Analysis|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Cardiovascular Disease 22 tppp3 28106390 Biochemistry 2017 10.1021/acs.biochem.6b00902 3 0 0 109 Animals|Humans|*Tubulin|*Polymerization|Microtubules|*Protein Binding|Nerve Tissue Proteins|Amino Acid Sequence|*Biological Evolution|Vertebrate|Invertebrate|HeLa Cells 22 TRAK2 29222186 J. Cell Biol. 2017 PMC5800816 10.1083/jcb.201708122 15 26 0 105 Humans|Animals|*Peroxisomes|Mitochondrial Proteins|Mitochondria|rho GTP-Binding Proteins|Microtubules|Neurons|Calcium|Cells, Cultured|*RNA Splicing|Receptors, Cytoplasmic and Nuclear 46 TRAK2 28655204 Eur. Heart J. 2017 PMC6251650 10.1093/eurheartj/ehx315 5 4 0 105 Humans|ABCA1 protein, human|*ATP Binding Cassette Transporter 1|ATP Binding Cassette Transporter, Subfamily G, Member 1|Cholesterol|Liver X Receptors|Apolipoprotein A-I|Lipoproteins, HDL|*Biological Transport|Atherosclerosis|HDL Cholesterol|Macrophages|ATP-Binding Cassette Transporters 46 TRAK2 28556983 J. Neurochem. 2017 PMC5554084 10.1111/jnc.14083 14 56 0 105 *Protein Kinase A|*Mitochondria|*Neurons|Mitochondrial Membranes|Mitochondrial Proteins|Phosphorylation|*Protein Transport|Protein Kinases|Parkinson Disease|Signal Transduction|Ubiquitin-Protein Ligases|Serine Threonine Kinases|rho GTP-Binding Proteins|Dendrites 46 TRAK2 28542283 PLoS ONE 2017 PMC5436667 10.1371/journal.pone.0177504 1 0 0 105 Humans|Genome-Wide Association Study|*Incidence|*Esophageal Cancer|Single Nucleotide Polymorphisms|Chinese|Genetic Predisposition to Disease|Genetic Loci|Carcinoma, Squamous Cell|Lung Cancer|Case-Control Studies|China|Risk Factors 46 TRAK2 28473328 Am. J. Physiol. Lung Cell Mol. Physiol. 2017 PMC5538870 10.1152/ajplung.00538.2016 6 2 0 105 Humans|*Mitochondria|*Muscle, Smooth|Sarcoplasmic Reticulum|*Respiratory System|Smooth Muscle Cells|Calcium|Excitation Contraction Coupling|Cytosol|Interleukin-13|*Lymphotoxin-alpha 46 TRAK2 28300646 Mol. Cell. Neurosci. 2017 PMC5400476 10.1016/j.mcn.2017.03.006 2 8 0 105 *Neurons|Axons|Dendrites|Axonal Transport|Kinesin|Mitochondria|Carrier Proteins|Hippocampus|Adaptor Proteins, Vesicular Transport|Protein Transport|Intracellular Signaling Peptides and Proteins|Mitochondrial Membranes|Dyneins|Green Fluorescent Proteins|Cells, Cultured|rho GTP-Binding Proteins|UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase|N-Acetylglucosaminyltransferases 46 TSHZ1 29255003 J. Neurosci. 2017 PMC5792476 10.1523/JNEUROSCI.1412-17.2017 5 0 0 48 Mice|Animals|*Amygdala|Extinction, Psychological|Fear|Interneurons|Knockout Mouse 42 TSHZ1 28981617 Cereb. Cortex 2017 PMC6095218 10.1093/cercor/bhx199 9 2 0 48 Humans|Mice|Animals|*Olfactory Bulb|*Neurogenesis|Neural Stem Cells|Interneurons|Subventricular Zone|Transcription Factors|Calbindin 2|Cell Movement|Cerebral Ventricles|Tyrosine 3-Monooxygenase|Sp8 protein, human|DNA-Binding Proteins|Sp8 protein, mouse 42 TSHZ1 28444170 Cereb. Cortex 2017 10.1093/cercor/bhx095 11 2 0 48 Mice|Animals|*DNA Methylation|*Hippocampus|BDNF protein, human|Brain-Derived Neurotrophic Factor|*Signal Transduction|*Neurons|Depressive Disorder|Neurogenesis|Stress, Psychological|Gene Expression Regulation|Transforming Growth Factor beta|Disease Models, Animal 42 TSPY1 29248931 Sex Dev 2017 10.1159/000484880 0 0 0 100 Humans|Female|Child, Preschool|Child|Adolescent|Young Adult|Adult|*Turner Syndrome|*Incidence|Gonadoblastoma|Dysgerminoma|sry Gene|Karyotyping|Chromosomes, Human, Y|Mosaicism|Karyotype|Cytogenetic Analysis|Virilism|In Situ Hybridization, Fluorescence|PCR|Ovarian Neoplasms 125 TSPY1 29027195 Clin. Pharmacol. Ther. 2017 PMC5899062 10.1002/cpt.907 2 42 0 100 Humans|Male|*Steroid 17-alpha-Hydroxylase|abiraterone|*Prostatic Neoplasms, Castration-Resistant|*Cytochrome P-450 CYP3A|Prospective Studies|Abiraterone Acetate|*Androstenes|Prednisone|Androgen Antagonists|Antineoplastic Agents, Hormonal|Cytochrome P-450 Enzyme Inhibitors|Disease-Free Survival|Kaplan-Meier Estimate|Antineoplastic Combined Chemotherapy Protocols|CYP3A4 protein, human|CYP17A1 protein, human|TSPYL1 protein, human|Nuclear Proteins 125 TSPY1 28881049 Histopathology 2017 10.1111/his.13387 1 0 0 100 Male|Humans|Female|*Gonadoblastoma|Germ Cell Neoplasms|Dysgenesis, Gonadal|Testicular Neoplasms|*Disorders of Sex Development|POU5F1 protein, human|Octamer Transcription Factor-3|Germinoma|*Gonad|Ovarian Neoplasms|Germ Cells|Biomarkers, Tumor|Sex Development 125 TSPY1 28847364 Reprod. Fertil. Dev. 2017 10.1071/RD17146 7 0 0 100 Humans|Male|*Case-Control Studies|*Testis|*Spermatogenesis|*Asian Continental Ancestry Group|Infertility, Male|Azoospermia|Oligospermia|*Phenotype|Haplotypes|Chromosomes, Human, Y|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Genes, Regulator|Sperm|Cell Cycle Proteins|Heterozygote|TSPY1 protein, human|TSPYL1 protein, human 125 TSPY1 28456834 Hum. Genet. 2017 10.1007/s00439-017-1793-8 19 0 0 100 Humans|Male|Oligozoospermia|Infertility, Male|Chromosomes, Human, Y|Azoospermia|Spermatogenesis|Chromosome Deletion|DNA Copy Number Variations|Haplotypes|Phenotype|Genotype 125 TSPY1 28332165 Med. Oncol. 2017 10.1007/s12032-017-0921-6 0 0 0 100 Pregnancy|Male|Female|Humans|In Situ Hybridization, Fluorescence|Microchimerism|*Tumors|*Antineoplastic Agents|Maternal-Fetal Exchange|Fetus|*B-Lymphocytes|PCR 125 TSPY1 28169398 Hum. Mol. Genet. 2017 PMC6075507 10.1093/hmg/ddx005 9 4 0 100 Humans|Male|AR protein, human|*Receptors, Androgen|*Testis|*Transcriptional Activation|*Proto-Oncogenes|Gonadoblastoma|Cell Cycle Proteins|Transcription Factors|DNA-Binding Proteins|Nuclear Proteins|Chromosomes, Human, Y|Oncogenesis|Prostate Cancer|Ovarian Neoplasms 125 TSPY1 28093458 Mol. Hum. Reprod. 2017 10.1093/molehr/gaw079 14 0 0 100 Male|Humans|*Spermatogonia|Spermatogenesis|Testis|Sertoli Cells|*B-Lymphocytes 125 TTC12 28624582 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.06.011 0 1 0 11 Adult|Humans|*Attention Deficit Disorder with Hyperactivity|Receptors, Peptide|SNPs|Receptors, G-Protein-Coupled|Genotype|Phenotype|*Gene Cluster|Epistasis, Genetic|Case-Control Studies|LPHN3 protein, human|TTC12 protein, human|Proteins 24 TTC7A 29229838 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5748228 10.1073/pnas.1718471115 7 0 0 51 Humans|1-Phosphatidylinositol 4-Kinase|Phosphoinositides|Phosphatidylinositol Phosphates|Phosphatidylinositol 4,5-Diphosphate|Plasma Membrane|Protein Transport|Protein Binding|Signal Transduction 34 TTC7A 29174094 Eur J Med Genet 2017 10.1016/j.ejmg.2017.11.014 2 0 0 51 Humans|*Mutation, Missense|Trichohepatoenteric Syndrome|Diarrhea, Infantile|Hair Diseases|*Inflammatory Bowel Disease|Facies|Intestinal Atresia, Multiple|Intestinal Atresia|Fetal Growth Retardation|*Syndrome|Mutations|*Intestine, Small|Phenotypes|DNA Helicases|Carrier Proteins|TTC7A protein, human|Proteins 34 TTC7A 28936210 Front Immunol 2017 PMC5594067 10.3389/fimmu.2017.01066 6 6 0 51 Humans|Infant, Newborn|Intestinal Atresia|Inflammatory Bowel Disease|Phenotype|Heterozygote|Genetic Predisposition to Disease|Mutation|IL10 protein, human|IL10 34 TTC7A 28555354 Fam. Cancer 2017 PMC5708147 10.1007/s10689-017-0006-x 1 0 0 51 Male|Humans|Middle Aged|*Colorectal Neoplasms, Hereditary Nonpolyposis|*Gene Deletion|DNA Mismatch Repair|MutS Homolog 2 Protein|Germ-Line Mutation|Microsatellite Instability|*Chromosome 3|Sigmoid Neoplasms|Genetic Testing|*Chromosome Structures|Antigens, Neoplasm|Epithelial Cell Adhesion Molecule|Pedigree|Adenocarcinoma|Mutations|Genotype|CRIPT protein, human|Adaptor Proteins, Signal Transducing 34 TTI2 29163555 Front Plant Sci 2017 PMC5681926 10.3389/fpls.2017.01723 1 5 0 57 *Zea mays|Molecular Chaperones|HSP90 Heat-Shock Proteins|Telomere-Binding Proteins|Protein-Serine-Threonine Kinases|Carrier Proteins|Phosphatidylinositol 3-Kinases 25 TTI2 28827813 PLoS Genet. 2017 PMC5578694 10.1371/journal.pgen.1006873 2 59 0 57 *Budding Yeast|Saccharomyces cerevisiae Proteins|Telomere-Binding Proteins|Saccharomyces cerevisiae|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|*Myosin-Light-Chain Kinase|*Protein Stability|Signal Transduction|Cell Cycle Checkpoints|DNA Damage|Protein Binding|MEC1 protein, S cerevisiae|Tel2 protein, S cerevisiae|TEL1 protein, S cerevisiae|PIH1 protein, S cerevisiae|Nuclear Proteins 25 TTI2 28648606 Structure 2017 PMC5501727 10.1016/j.str.2017.05.016 0 13 0 57 Cryoelectron Microscopy|*Molecular Chaperone|*HSP90 Heat-Shock Proteins|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Small Nucleolar Ribonucleoproteins|Nuclear Proteins|Adenosine Triphosphatases|DNA Helicases|Transcription Factors|Multiprotein Complexes|RNA Polymerase II|Protein Binding 25 TTI2 28576863 Genetics 2017 PMC5560794 10.1534/genetics.117.203232 0 7 0 57 *tRNA|RNA, Transfer, Pro|Anticodon|Genetic Code|Codon|Protein Biosynthesis|Saccharomyces cerevisiae|*Phenotypes|Allele|Mutation 25 TTI2 28461460 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5441779 10.1073/pnas.1703498114 7 3 0 57 *Zea mays|Endosperm|Plant Proteins|Transposable Element|Alleles 25 TWSG1 28928871 J Cancer 2017 PMC5604214 10.7150/jca.18482 1 38 0 895 Humans|*Thyroid Cancer, Papillary|*Gastrulation|Bone Morphogenetic Proteins|*Cell Motility|Signal Transduction|Cell Differentiation|Cell Proliferation|Growth Factors|Matrix Metalloproteinase 2|Thyroid Neoplasms 47 TWSG1 28501597 Exp. Hematol. 2017 10.1016/j.exphem.2017.05.002 2 5 0 895 HAMP protein, human|*Hepcidins|*Erythropoiesis|Iron Overload|Iron|Anemia|Iron Metabolism Disorders|metal transporting protein 1|Cation Transport Proteins|Homeostasis|GDF11 protein, human|Bone Morphogenetic Proteins|GDF15 protein, human|GDF-15|Gene Expression Regulation|Signal Transduction 47 TWSG1 28135344 PLoS ONE 2017 PMC5279787 10.1371/journal.pone.0171054 4 12 0 895 Mice|Animals|HAMP protein, human|*Hepcidins|*Anemia|Erythropoiesis|Iron|Iron Overload|phenylhydrazine|Phenylhydrazines|Erythropoietin|Hemoglobin|Hemolysis|Dietary Iron|Liver|Upregulation|Disease Models, Animal 47 txnl1 29231889 Int J Mol Sci 2017 PMC5751295 10.3390/ijms18122694 3 0 0 480 Animals|*Isoptera|*Caste 37 txnl1 28925510 Clin. Exp. Pharmacol. Physiol. 2017 10.1111/1440-1681.12856 11 1 0 480 Mice|Animals|NeuroD protein|*Basic Helix-Loop-Helix Transcription Factors|*Injury, Spinal Cord|*Nerve Tissue Proteins|MicroRNAs|Downregulation|*Oxidative Stress|Microglia|Inflammation|Disease Models, Animal|SEPN1 protein, mouse|Muscle Proteins|Selenoproteins 37 txnl1 28553621 Front Cell Infect Microbiol 2017 PMC5427065 10.3389/fcimb.2017.00178 6 7 0 480 37 UBAP2L 29196913 Breast Cancer 2017 PMC5818569 10.1007/s12282-017-0820-x 6 13 0 157 *Cell Proliferation|Cell Line, Tumor|Hepatocellular Carcinoma|Cyclin B1|RNA, Small Interfering|Gene Knockdown Techniques|Carrier Proteins|Colorectal Carcinoma|Liver Neoplasms|Cell Division 21 UBAP2L 28981479 Med. Sci. Monit. 2017 PMC5639951 10.12659/msm.907071 10 4 0 157 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Prognosis|Kaplan-Meier Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Disease-Free Survival|Neovascularization, Pathologic|Multivariate Analysis|Western Blotting|Ubiquitins|Ubap2L protein, human|Carrier Proteins 21 UBAP2L 28754713 FASEB J. 2017 10.1096/fj.201601219RRR 3 0 0 157 Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|A549 Cells|Neoplasm Proteins|Adenocarcinoma|Cell Line, Tumor|Cell Movement|Cell Proliferation|Signal Transduction 21 UBAP2L 28334716 Cell. Physiol. Biochem. 2017 10.1159/000470824 5 6 0 157 *Carcinoma, Hepatocellular|*Epithelial-Mesenchymal Transition|*Down-Regulation|*Liver Neoplasms|Snail Family Transcription Factors|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|RNA Interference|Cell Movement|Cell Line, Tumor|Cadherins|Transcription Factors 21 ULK4 29034508 Glia 2017 10.1002/glia.23236 1 0 0 17 Mice|Animals|Oligodendrocytes|Myelin|Demyelinating Diseases|Transcription Factors|Mice, Transgenic|Myelin Basic Protein|Basic Helix-Loop-Helix Transcription Factors|Nerve Tissue Proteins|Cell Differentiation|Gene Expression Regulation, Developmental|B Fibers|Brain|Animals, Newborn 27 ULK4 28596978 Neurogenesis (Austin) 2017 PMC5449176 10.1080/23262133.2017.1313646 2 0 0 17 *Neurogenesis|Neural Stem Cells|Subventricular Zone|Neurons|Cell Cycle|Cell Proliferation|Signal Transduction|*Nervous System Physiological Phenomena|Brain 27 ULK4 28596815 World J Stem Cells 2017 PMC5440771 10.4252/wjsc.v9.i5.77 1 0 0 17 Humans|*Induced Pluripotent Stem Cells|*Cells, Cultured|*Sequencing, Next-Generation|Cellular Reprogramming|Cell Differentiation|Fibroblasts|*Cancer 27 UPK1A 28138557 JCI Insight 2017 PMC5256140 10.1172/jci.insight.89560 6 0 0 118 Humans|*Urinary Bladder Neck Obstruction|*miRNA|*Urinary Bladder|Phosphatidylinositol 3-Kinases|*Signal Transduction|Urodynamic|mRNA|*Biomarkers|Urinary Bladder, Overactive|Gene Expression Profiling|NF-kappa B|Lower Urinary Tract Symptoms|Transcriptome|*Biological Phenomena 66 UPK1A 28099513 PLoS ONE 2017 PMC5242461 10.1371/journal.pone.0170196 3 2 0 118 Humans|Animals|Phylogeny|*Uroplakins|Tspan3 protein, human|*Tetraspanins|TSPAN32 protein, human|Genetic Evolution|Gene Duplication|Vertebrates|*Phosphotyrosine Phosphatase|*Biological Evolution|Multigene Family|Sequence Alignment|Conserved Sequence|Amino Acid Sequence|Integral Membrane Proteins|Membrane Glycoproteins|Intron|Exon 66 UPK2 29027273 Int. J. Urol. 2017 10.1111/iju.13429 0 0 0 81 Humans|*Lymphatic Metastasis|*Lymphadenectomy|*Cancer, Urinary Tract|Keratin-20|Lymph Nodes|Neoplasm Staging|Biomarkers, Tumor|Neoplasm Proteins|RNA, Messenger|*Urinary Tract 124 UPK2 28954463 Int Neurourol J 2017 PMC5636959 10.5213/inj.1734898.449 7 1 0 81 Rats|Animals|*Cystitis, Interstitial|*Disease Models, Animal|Bladder|Cystitis|Administration, Intravesical|Cyclophosphamide 124 UPK2 28786878 Am. J. Surg. Pathol. 2017 10.1097/PAS.0000000000000922 2 0 0 81 Female|*Urinary Bladder|*Carcinoma, Transitional Cell|Uroplakin II|GATA3 protein, human|GATA3 Transcription Factor|Immunohistochemistry|Urinary Bladder Neoplasms|Urothelium|Carcinoma, Signet Ring Cell|Receptors, Estrogen|Biomarkers, Tumor|*Urologic Neoplasms|Tissue Array Analysis|Adenocarcinoma|Biopsy|CEACAM5 protein, human|Carcinoembryonic Antigen|progesterone receptor B 124 UPK2 28388658 PLoS ONE 2017 PMC5384764 10.1371/journal.pone.0175290 6 13 0 81 Humans|Male|*Urinary Bladder Neoplasms|*Prognosis|FGFR3 protein, human|Receptor, Fibroblast Growth Factor, Type 3|Death-Associated Protein Kinases|Apoptosis|Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|DNA Methylation|RNA, Messenger|Autophagy|Promoter Regions, Genetic|Upregulation|DAPK1 protein, human 124 UPK2 28291125 Am. J. Surg. Pathol. 2017 10.1097/PAS.0000000000000798 0 0 0 81 Humans|Male|*Prostate|GATA3 protein, human|*GATA3 Transcription Factor|kallikrein-related peptidase 3, human|Prostate Specific Antigen|Immunohistochemistry|Carcinoma, Transitional Cell|Urothelium|Uroplakin 2|Prostatic Neoplasms|Urinary Bladder Neoplasms|Biomarkers, Tumor|Adenocarcinoma|Tissue Array Analysis|Urologic Neoplasms|Diagnosis, Differential|Biopsy|Predictive Value of Tests 124 UPK2 28192514 PLoS ONE 2017 PMC5305210 10.1371/journal.pone.0172416 0 0 0 81 *Uroplakins|TSPAN32 protein, human|*Tetraspanins|*Phosphotyrosine Phosphatase|*Biological Evolution|Receptor-Like Protein Tyrosine Phosphatases, Class 3|Amino Acid Sequence 124 UPK2 28099513 PLoS ONE 2017 PMC5242461 10.1371/journal.pone.0170196 3 2 0 81 Humans|Animals|Phylogeny|*Uroplakins|Tspan3 protein, human|*Tetraspanins|TSPAN32 protein, human|Genetic Evolution|Gene Duplication|Vertebrates|*Phosphotyrosine Phosphatase|*Biological Evolution|Multigene Family|Sequence Alignment|Conserved Sequence|Amino Acid Sequence|Integral Membrane Proteins|Membrane Glycoproteins|Intron|Exon 124 URAD 29236228 Clin Pharmacokinet 2017 10.1007/s40262-017-0617-2 5 0 0 3 *Ropivacaine|*Anesthesia, Spinal|Anesthetics, Local|Amides|Double-Blind Method 55 URAD 28541755 Exp. Lung Res. 2017 10.1080/01902148.2017.1323981 0 2 0 3 Animals|Rats|*Anaphylaxis|*Epinephrine|AVP protein, human|*Neurophysins|*Vasopressin|Hypotension|Arginine Vasopressin|*Shock|Blood Pressure|Vasodilatation 55 USP29 29196261 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.11.180 0 0 0 22 Mice|Animals|*Chondrocytes|A-674563|SOX9 protein, human|*SOX9 Transcription Factor|Pyridines|Articular Cartilage|Collagen Type II|Cells, Cultured|Gene Expression Regulation|*Biomarkers|Cell Proliferation|Sox9 protein, mouse 34 USP29 28925797 Epigenetics 2017 PMC5788428 10.1080/15592294.2017.1377869 10 0 0 22 Female|Animals|Mice|*DNA Methylation|Genomic Imprinting|Kruppel-Like Transcription Factors|Upregulation|Gene Expression Regulation, Developmental|Alleles|Nerve Tissue Proteins|Transcriptional Activation|Ubiquitin-Specific Proteases|Downregulation|Mutation|Peg3 protein, mouse|Zim1 protein, mouse|Carrier Proteins 34 USP29 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 22 Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human 34 USP29 28743993 Sci Rep 2017 PMC5526879 10.1038/s41598-017-06817-5 3 1 0 22 Male|Female|Animals|Mice|*Mice, Inbred ICR|*YY1 Transcription Factor|Genomic Imprinting|DNA Methylation|Kruppel-Like Transcription Factors|Binding Sites|Transcriptional Activation|Up-Regulation|Allele|Ubiquitin-Specific Proteases|Downregulation|Peg3 protein, mouse|Yy1 protein, mouse|Zim1 protein, mouse|Carrier Proteins|Nerve Tissue Proteins 34 USP29 28719641 PLoS ONE 2017 PMC5515438 10.1371/journal.pone.0181591 3 2 0 22 Animals|Mice|*Mice, Inbred ICR|Genomic Imprinting|DNA Methylation|Kruppel-Like Transcription Factors|Alleles|Ubiquitin-Specific Proteases|*Chromosome Inversion|Promoter Regions, Genetic|Exons|Genomics|Peg3 protein, mouse 34 USP29 28569192 BMC Genomics 2017 PMC5452331 10.1186/s12864-017-3811-6 2 0 0 22 Humans|*mRNA|*Binding Sites|3' Untranslated Regions|miRNA 34 UTF1 29222434 Sci Rep 2017 PMC5722945 10.1038/s41598-017-17482-z 1 4 0 98 Male|Female|Pregnancy|Mice|Animals|*Cell Differentiation|Embryonic Stem Cells|Transcription Factors|Pluripotent Stem Cells|Trans-Activators|Chromosomal Proteins, Non-Histone|Nuclear Proteins|Gene Expression Regulation, Developmental|Chromatin|Spermatogonia|Embryonic Development|Cell Lineage|Spermatogenesis|Testis|Utf1 protein, mouse|Dnd1 protein, mouse|Neoplasm Proteins 110 UTF1 29193985 Syst Biol Reprod Med 2017 10.1080/19396368.2017.1406013 2 0 0 98 Humans|Male|Mice|Animals|Spermatogonia|Adult Germline Stem Cells|Testis|Spermatogenesis|Flow Cytometry|Cell Separation|Cells, Cultured|*B-Lymphocytes|Cell Culture Techniques|Cell Proliferation|Biomarkers|*Diploidy 110 UTF1 29097685 Sci Rep 2017 PMC5668265 10.1038/s41598-017-14426-5 0 11 0 98 Mice|Male|Animals|Pluripotent Stem Cells|Embryonic Stem Cells|Trans-Activators|POU5F1 protein, human|Octamer Transcription Factor-3|Cell Differentiation|Chromosomal Proteins, Non-Histone|Germ Line|SOX2 protein, human|SOXB1 Transcription Factors|Cell Line|*Epigenetic|Epigenesis, Genetic|Utf1 protein, mouse 110 UTF1 28836968 BMC Urol 2017 PMC5571510 10.1186/s12894-017-0254-y 0 0 0 98 Humans|Male|*Testis|Orchiopexy|Cryptorchidism|*Diffusion Magnetic Resonance Imaging|Laparoscopy|Magnetic Resonance Spectroscopy 110 UTF1 28827392 Development 2017 10.1242/dev.150284 12 0 0 98 Male|Humans|*Spermatogonia|*Kinetics|Spermatogenesis|Glial Cell Line-Derived Neurotrophic Factor Receptors|Testis|Stem Cells|Cell Differentiation 110 VIPAS39 29046204 Zhongguo Dang Dai Er Ke Za Zhi 2017 0 0 0 57 Infant|Humans|Female|Arthrogryposis renal dysfunction cholestasis syndrome|*Arthrogryposis|Renal Insufficiency|*Cholestasis|*Mutations|Heterozygote|Vesicular Transport Proteins|*Syndrome|Phenotype|Liver|Glutamyl Transpeptidase|VPS33B protein, human 24 VIPAS39 28039895 Clin. Genet. 2017 10.1111/cge.12959 4 0 0 57 Child|Humans|Retrospective Studies|*Cholestasis|Sequencing, Next-Generation|Mutation|Phenotype|Pedigree|*Genetic Profile|Genetic Predisposition to Disease|Liver Diseases 24 VSX1 29111844 Ophthalmic Genet. 2017 10.1080/13816810.2017.1393831 5 0 0 45 Humans|*Keratoconus|Genome-Wide Association Study|Eye Proteins|Homeodomain Proteins|Mutations|Superoxide Dismutase-1|Polymorphism, Single Nucleotide|Frequencies, Allele|Superoxide Dismutase|MIRN184 microRNA, human|MicroRNAs 115 VSX1 28950846 BMC Ophthalmol 2017 PMC5615802 10.1186/s12886-017-0567-3 4 0 0 45 Humans|*Keratoconus|Eye Proteins|Homeodomain Proteins|Chinese|China|Mutation|Case-Control Studies|VSX1 protein, human 115 VSX1 28540003 J Ophthalmic Vis Res 2017 PMC5423365 10.4103/jovr.jovr_97_16 4 1 0 45 Eye Proteins|Keratoconus|Base Sequence|Homeodomain Proteins|Mutations|Superoxide Dismutase-1|Superoxide Dismutase|Polymerase Chain Reaction 115 VSX1 28164597 Clin. Lab. 2017 10.7754/Clin.Lab.2016.160144 1 0 0 45 Humans|*Keratoconus|*Genes, Homeobox|*Genetic Testing|*DNA Primers|Eye Proteins|Base Sequence|Homeodomain Proteins|Asians|Genetic Predisposition to Disease|Single Nucleotide Polymorphisms|Mutation|*Nucleic Acid Amplification Techniques|DNA|VSX1 protein, human 115 VSX1 28148823 Open Biol 2017 PMC5356445 10.1098/rsob.160312 6 2 0 45 Animals|*Zebrafish|*Central Nervous System|Zebrafish Proteins|Embryo, Nonmammalian|Spinal Cord|Hindbrain|Neurons|Neural Stem Cells|Neurogenesis|Receptors, Notch|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Telencephalon|Cell Differentiation|Brain|Signal Transduction|*Embryo, Mammalian|Retina 115 VSX1 28082864 Front Mol Neurosci 2017 PMC5183629 10.3389/fnmol.2016.00145 3 11 0 45 Mice|Animals|*Interneuron|*Spinal Cord|Motor Neurons|Transcription Factors|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Eye Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Neural Tube 115 WDFY4 28719732 2017 PMC5874801 10.1002/art.40216 9 2 0 12 Humans|Child|*Genome-Wide Association Study|*Arthritis, Juvenile|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Rheumatoid Factor|Case-Control Studies 20 WDFY4 28062664 Hum. Mol. Genet. 2017 PMC5409091 10.1093/hmg/ddw417 10 4 0 12 *RNA-Seq|Bayes Theorem|Quantitative Trait Loci|*Lupus Erythematosus, Systemic|Genome-Wide Association Study|*Alternative Splicing|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Whole Exome Sequencing|Haplotypes|Gene Expression|Exon|Case-Control Studies|RNA, Untranslated 20 WFDC1 28529272 J. Vet. Med. Sci. 2017 PMC5559356 10.1292/jvms.17-0078 1 0 0 69 Peters anomaly|*Corneal Opacity|*Anterior Eye Segment|Anterior segment mesenchymal dysgenesis|*Eye Abnormalities|*Aphakia|*Corneal Diseases|Cornea|Iris 42 WHAMM 28720660 Mol. Biol. Cell 2017 PMC5597322 10.1091/mbc.E17-01-0022 5 16 0 1784 Humans|*Arp2-3 Complex|*Amish|phosphatidylinositol 3-phosphate|Galloway Mowat syndrome|Nephrosis|Microcephaly|Hernia, Hiatal|Homozygote|Microtubule-Associated Proteins|Nephrotic Syndrome|Membrane Proteins|Mutations|Pedigree|Models, Molecular|Phenotype|WHAMM protein, human 33 WHAMM 28646090 J. Cell. Sci. 2017 PMC5536917 10.1242/jcs.199570 29 0 0 1784 *Wiskott-Aldrich Syndrome Protein Family|Arp2-3 Complex|Actin|Wiskott-Aldrich Syndrome Protein, Neuronal|Wiskott-Aldrich Syndrome Protein|Filopodia|Endocytosis|*B Cells|Endoplasmic Reticulum 33 WHAMM 28351611 J. Mol. Biol. 2017 10.1016/j.jmb.2017.03.022 5 3 0 1784 *Cryoelectron Microscopy|*Microtubules|Tubulin|Microtubule-Associated Proteins|Protein Conformation|Protein Binding|Actin|Models, Molecular|Polymerization 33 XPO4 28790116 Clin. Cancer Res. 2017 10.1158/1078-0432.CCR-17-0474 7 0 0 139 35 XPO4 28773887 Materials (Basel) 2017 PMC5457063 10.3390/ma9090766 0 1 0 139 Lithium|Electric Power Supplies|Electrodes|Iron|Phosphates|Electrochemical Techniques|Manganese|Oxides 35 XPO4 28598468 Dalton Trans 2017 10.1039/c7dt01375b 2 0 0 139 *Metals, Rare Earth|Cerium|Luminescent Agents|Luminescence|*Cations 35 YBEY 28805544 RNA Biol 2017 PMC5731808 10.1080/15476286.2017.1356565 4 0 0 103 *RNA Interference|Sinorhizobium meliloti|Host Factor 1 Protein|*Symbiosis|RNA, Bacterial|RNA, Small Untranslated|Gene Expression Regulation, Bacterial|ribonuclease E|Endoribonucleases|*Plant|Medicago sativa 37 YBEY 28579982 Front Microbiol 2017 PMC5437115 10.3389/fmicb.2017.00910 4 10 0 103 Humans|*Ribonucleases|*Virulence|RNA, Bacterial|Gene Expression Regulation, Bacterial|Contamination, Food|Bacteria 37 YBEY 28180335 Nucleic Acids Res. 2017 PMC5388416 10.1093/nar/gkw1234 12 9 0 103 *Sinorhizobium meliloti|Host Factor 1 Protein|*Endoribonucleases|Gene Expression Regulation, Bacterial|RNA, Bacterial|Escherichia coli Proteins|Symbiosis|*Catalysis|mRNA|Double-Stranded RNA 37 YBEY 28153719 Biochem. Biophys. Res. Commun. 2017 PMC5318257 10.1016/j.bbrc.2017.01.149 4 6 0 103 Humans|*Bacterial Proteins|Escherichia coli Proteins|Escherichia coli|RNA, Bacterial|Metalloproteins|Ribosomes|Gene Expression Regulation, Bacterial|RNA, Ribosomal, 16S|Endoribonucleases|YbeY protein, E coli 37 YBX2 29227750 Genet Test Mol Biomarkers 2017 10.1089/gtmb.2017.0040 1 0 0 47 Male|Humans|Female|*Infertility, Male|Protamines|Sperm|Spermatogenesis|Polymorphism, Single Nucleotide|Case-Control Studies|YBX2 protein, human|RNA-Binding Proteins|PRM1 protein, human 92 YBX2 29109362 J. Reprod. Dev. 2017 PMC5830355 10.1262/jrd.2017-106 3 3 0 47 Male|Mice|Animals|*Spermiogenesis|*Polynucleotide Adenylyltransferase|Spermatids|Testis|mRNA|messenger ribonucleoprotein|Ribonucleoproteins|Polyribosomes|Cytoplasm|*Organelles|Argonaute Proteins|Ybx2 protein, mouse|RNA-Binding Proteins|Piwil1 protein, mouse 92 YBX2 28970281 Diabetes 2017 10.2337/db17-0655 4 0 0 47 Mice|Animals|*Adipose Tissue, Brown|Thermogenesis|Uncoupling Protein 1|Adipose Tissue, White|Adipocytes, Brown|Adipogenesis|*RNA Stability|Transcription Factors|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Gene Expression Regulation|mRNA|TYRP1 protein, human|*Membrane Glycoproteins|Mitochondrial Proteins|Mice, Knockout|Cell Differentiation|MicroRNAs|RNA-Binding Proteins 92 YBX2 28263985 PLoS Genet. 2017 PMC5367891 10.1371/journal.pgen.1006589 19 2 0 47 Humans|Female|Receptors, Estrogen|*Isoforms|MCF7 Cells|Estrogen Receptor alpha|Alternative Splicing|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Sequencing, RNA|RNA, Messenger|Cell Line, Tumor|Cohort Studies|PCBP2 protein, human|RNA-Binding Proteins|YBX1 protein, human|Y-Box-Binding Protein 1 92 ZBED3 28992324 J Mol Cell Biol 2017 10.1093/jmcb/mjx035 1 0 0 98 Female|Mice|Animals|Zygotes|Embryogenesis|Oocytes|*Organelles|*Cytoplasm|Embryo, Mammalian|Blastocyst|Gene Expression Regulation, Developmental|Transcription Factors 21 ZBED3 28431932 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.04.090 7 8 0 98 Humans|*Chondrogenesis|*RNA, Long Noncoding|*Synovial Fluid|*Mesenchymal Stem Cells|Cell Differentiation|Chondrocytes|Transcription Factors|Cell Proliferation|Cells, Cultured|Signal Transduction|ZBED3 protein, human|DNA-Binding Proteins 21 ZBED3 28346859 Metab Syndr Relat Disord 2017 10.1089/met.2016.0122 1 1 0 98 Humans|*Metabolic Syndrome|Diabetes Mellitus, Type 2|Cross-Sectional Studies|Insulin Resistance|Blood Glucose|ZBED3 protein, human|DNA-Binding Proteins|Transcription Factors 21 ZBTB18 29158550 Eur. J. Hum. Genet. 2017 PMC5865117 10.1038/s41431-017-0022-1 9 0 0 323 Humans|*Exome|Pilot Projects|*Neurodevelopmental Disorders|Whole Exome Sequencing|Genetic Testing|Genetic Predisposition to Disease|Genes, X-Linked|RIT1 protein, human|ras Proteins 41 ZBTB18 28943935 Oncol Lett 2017 PMC5592857 10.3892/ol.2017.6657 0 0 0 323 Humans|Regulatory Network, Gene|Gene Ontology|Protein Interaction Maps|Gene Expression Profiling|Computational Biology|RNA, Micro|*Microarray Analysis|Transcriptome|Cluster Analysis|Gene Expression Regulation, Neoplastic|*Osmosis|*Biological Phenomena|*Intervertebral Discs 41 ZBTB18 28749472 Cell Death Dis 2017 PMC5550877 10.1038/cddis.2017.336 6 23 0 323 Mice|Animals|*Retinoic Acid|*Up-Regulation|*Embryonic Stem Cells|*Cell Differentiation|*Nerve Cells|mESCs|MicroRNAs|Cell Line|Basic Helix-Loop-Helix Transcription Factors|*Transcriptional Activation|herstatin|Intercellular Signaling Peptides and Proteins|Networks, Gene|MIRN219 microRNA, mouse 41 ZBTB18 28512252 Mol. Cancer Res. 2017 PMC5967621 10.1158/1541-7786.MCR-16-0494 3 13 0 323 *Glioblastoma|*Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|DNA Methylation|Cell Proliferation|*Disease Progression|Cell Line, Tumor|MicroRNAs|Cell Movement|Genes, Tumor Suppressor|Transcription Factors 41 ZBTB18 28506232 Neural Dev 2017 PMC5433244 10.1186/s13064-017-0084-3 4 22 0 323 Humans|Animals|Infant, Newborn|Cerebral Cortex|Neural Stem Cells|Neurogenesis|Neurons|Cell Differentiation|Cell Movement|Gene Expression Regulation, Developmental|Repressor Proteins|Transcription Factors 41 ZBTB38 29287967 J. Mol. Biol. 2017 10.1016/j.jmb.2017.12.014 10 0 0 165 *DNA Methylation|*Zinc Fingers|CpG Islands|Protein Binding|DNA|DNA-Binding Proteins|Transcription Factors|Repressor Proteins|Amino Acid Sequence|Promoter Regions, Genetic|Models, Molecular 43 ZBTB38 29216791 Prion 2017 PMC5871027 10.1080/19336896.2017.1405885 3 0 0 165 Humans|Animals|*Fatal Familial Insomnia|*Polymorphism, Single Nucleotide|*Creutzfeldt-Jakob Syndrome|Prions|Prion Diseases|Prion Proteins|Genetic Predisposition to Disease|Genotype|*Chinese|Protein 14-3-3|Myoclonus|*Genes, Regulator|Case-Control Studies|MicroRNAs|RASA2 protein, human|ras GTPase-Activating Proteins|ZBTB38 protein, human|Repressor Proteins 43 ZBTB38 29059699 Hepatol. Res. 2017 10.1111/hepr.12992 6 3 0 165 *Non-alcoholic Fatty Liver Disease|*Epigenesis, Genetic|CpG Islands|*Genome|DNA Methylation|*Disease Progression|*Genomics|Liver|Protein Processing, Post-Translational 43 ZBTB38 28744006 Sci Rep 2017 PMC5527114 10.1038/s41598-017-06766-z 5 7 0 165 Humans|Genome-Wide Association Study|Taiwan|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Loci|Genetic Predisposition to Disease|Multifactorial Inheritance|Genotype|Case-Control Studies|CDK10 protein, human|Cyclin-Dependent Kinases|Genes, cdc|Risk Factors|CABLES1 protein, human|Carrier Proteins|Phosphoproteins|Cyclins|ZNF638 protein, human 43 ZBTB38 28514761 Oncotarget 2017 PMC5542192 10.18632/oncotarget.17487 3 21 0 165 Humans|Mice|Animals|*Injury, Spinal Cord|Endoplasmic Reticulum Stress|Recovery of Function|Spinal Cord|Apoptosis|Transcription Factor|Oligodendroglia|Locomotion|Activation, Transcription|ZBTB38 protein, human|Repressor Proteins 43 ZBTB38 28238764 J. Mol. Biol. 2017 PMC5395100 10.1016/j.jmb.2017.02.012 7 20 0 165 Humans|Mice|Animals|Cullin 1|*Cullin Proteins|NEDD8 protein, human|NEDD8 Protein|E3 Ubiquitin Ligase|Ubiquitins|*Cell Differentiation|Ubiquitin|pevonedistat|Cyclopentanes|Pyrimidines|Myoblasts|*Ubiquitination|Muscle Atrophy|Cachexia|Protein Processing, Post-Translational|Neoplasms|Transcription Factors 43 ZC3H13 28805815 Nat. Neurosci. 2017 PMC5614841 10.1038/nn.4620 35 7 0 158 Humans|Mice|Animals|*Glioblastoma|*Clustered Regularly Interspaced Short Palindromic Repeats|Temozolomide|Dacarbazine|Brain Neoplasms|Antineoplastic Agents, Alkylating|DNA Modification Methylases|KMT2C protein, human|DNA-Binding Proteins|Mutations|PTEN protein, human|PTEN Phosphohydrolase|DNA Mutational Analysis|Adeno-Associated Virus 22 ZC3H14 28793261 Cell Rep 2017 PMC5577809 10.1016/j.celrep.2017.07.038 7 41 0 116 Humans|Animals|Mice|*Drosophila|Nab2 protein, Drosophila|Drosophila Proteins|*Neurons|Drosophila melanogaster|Fragile X Mental Retardation Protein|Fragile X Syndrome|mRNA|Axons|Gene Expression Regulation, Developmental|REG1A protein, human|*Lithostathine|RNA|Brain|Hippocampus|CaM KII|Smell|ZC3H14 protein, human 23 ZC3H14 28666327 Hum. Mol. Genet. 2017 PMC5886104 10.1093/hmg/ddx248 7 0 0 116 Humans|Animals|Mice|Proteomics|*RNA Binding Protein|*RNA, Messenger|Drosophila Proteins|Nuclear Proteins|RNA|polyadenosine|Adenosine|Conserved Sequence|Exon|Neurons|Polymers|Brain|ZC3H14 protein, human 23 ZDHHC9 28687527 Eur J Med Genet 2017 10.1016/j.ejmg.2017.07.002 5 0 0 61 Male|Humans|Infant|Child, Preschool|*Intellectual Disability|*Genes, X-Linked|*Sequencing, Next-Generation|Mental Retardation, X-Linked|Mutation|Pedigree|Phenotype|Missense Mutation|Epilepsy|Acyltransferases|ZDHHC9 protein, human 30 ZDHHC9 28168288 Cereb. Cortex 2017 PMC6600876 10.1093/cercor/bhx027 5 3 0 61 Adult|Humans|Neural Pathways|Brain|Brain Mapping|White Matter|Nerve Net|Cognition Disorders|Magnetic Resonance Imaging|Image Processing, Computer-Assisted|*Disorder, Neurodevelopmental|Neuropsychological Tests|Intellectual Disability|ZDHHC9 protein, human|Acyltransferases 30 zfhx4 29081410 Cancer Biomark 2017 10.3233/CBM-170541 0 0 0 66 Humans|*Basal Cell Nevus Syndrome|*Whole Exome Sequencing|PTCH2 protein, human|Patched-2 Receptor|*Chinese|Patched-1 Receptor|Exome|Pedigree|Mutation|Genetic Linkage 26 zfhx4 28694483 Sci Rep 2017 PMC5504002 10.1038/s41598-017-04221-7 3 8 0 66 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Prospective Studies|*Chinese|Prognosis|Gene Expression Regulation, Neoplastic|Downregulation|Mutations|Cell Migration|Cell Line, Tumor 26 ZFP36L2 28882690 Pharmacol. Res. 2017 10.1016/j.phrs.2017.08.018 3 0 0 866 Humans|*Curcumin|*Computational Biology|*Toxicogenetics|Melanoma|Vemurafenib|Proto-Oncogene Proteins B-raf|Drug Resistance, Neoplasm|Cell Line, Tumor|Protein Kinase Inhibitors|Signal Transduction 71 ZFP36L2 28860350 Gut 2017 PMC5980794 10.1136/gutjnl-2017-314607 16 8 0 866 Humans|*Esophageal Squamous Cell Carcinoma|Esophageal Neoplasms|*Adenocarcinomas|*Mutations|Carcinoma, Squamous Cell|Exome|Genome, Human|Genomics|Transcription Factors 71 ZHX2 29119102 Int J Genomics 2017 PMC5651161 10.1155/2017/4858173 0 9 0 190 Humans|*Gene Regulatory Networks|Transcription Factors|Transcription, Genetic|Gene Expression Regulation, Bacterial|Escherichia coli K12|Models, Genetic|Databases, Genetic|*Myeloid Progenitor Cells|Escherichia coli|*Myeloid Cell 78 ZIC4 28503614 Child Neurol Open 2017 PMC5417291 10.1177/2329048X16666362 0 0 1 48 Humans|Female|Blepharophimosis, Ptosis, and Epicanthus Inversus|*Blepharophimosis|*Dandy-Walker Syndrome|Wisconsin|*Skin Abnormalities|*Urogenital Abnormalities|Forkhead Box Protein L2|Chromosome Deletion|Phenotype|Forkhead Transcription Factors|*Chromosome Structures 76 ZMIZ1 29198723 Am. 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Genet. 2017 PMC5812919 10.1016/j.ajhg.2017.09.028 17 6 0 162 Humans|*DNA Methylation|Genome-Wide Association Study|*Blood Pressure|Cross-Sectional Studies|CpG Islands|Epigenesis, Genetic|Mendelian Randomization Analysis|Quantitative Trait Loci|Genome, Human|Phenotype|Risk Factors|African Americans 65 ZMIZ1 28814769 Sci Rep 2017 PMC5559619 10.1038/s41598-017-09170-9 8 0 0 162 Female|Humans|*Genome-Wide Association Study|*Phenotype|Quantitative Trait Loci|Dairy Industry|Fertility|Breeding|SNPs|Genotype|*Chinese 65 ZNF185 29062885 Clin Nutr Exp 2017 PMC5650108 10.1016/j.yclnex.2017.04.001 7 11 0 64 Humans|Male|arctigenin|*Lignans|*Furans|*Prostatic Neoplasms|*Cell Proliferation|Cell Line, Tumor|Xenograft Model Antitumor Assays|*Cell Cycle|Tumor Burden 24 ZNF185 28927124 Oncol Lett 2017 PMC5587964 10.3892/ol.2017.6633 2 0 0 64 Humans|*Carcinoma, Pancreatic Ductal|*Prognosis|Pancreatic Neoplasms|Cell Line, Tumor|*Plasma Membrane|Upregulation|Immunohistochemistry|ZNF185 protein, human|Cytoskeletal Proteins|LIM Domain Proteins 24 ZNF185 28627666 Mol Med Rep 2017 10.3892/mmr.2017.6797 1 2 0 64 Male|Mice|Animals|*Testis|Leydig Cells|Sertoli Cells|Testosterone|Luteinizing Hormone|Sperm|*Cell Communication|Cytoplasm|Cell Differentiation|Blotting, Western|*Biological Transport|Zinc Fingers|ZNF185 protein, mouse|LIM Domain Proteins 24 ZNF185 28276460 Sci Rep 2017 PMC5343450 10.1038/srep43813 7 3 0 64 Humans|*Genomics|*Disease Progression|*Neoplastic Processes|*Genome|Sequencing, Whole Exome|Mutations|Biomarkers, Tumor|DNA Copy Number Variations|Liver Neoplasms 24 ZNF185 28143451 BMC Cancer 2017 PMC5286827 10.1186/s12885-017-3087-x 14 1 0 64 Humans|Male|*Prostate|*Messenger RNA|*Extracellular Vesicle|*Prostate Cancer|Exosomes|Cell-Derived Microparticles|Cell Line, Tumor|Biomarkers, Tumor 24 ZNF365 29042450 FASEB J. 2017 10.1096/fj.201700694R 1 0 0 33 Animals|*Zebrafish|lipopolysaccharide-binding protein|*Gram-Negative Bacterial Infections|*Carrier Proteins|*Acute-Phase Proteins|*Membrane Glycoproteins|Aeromonas hydrophila|Zebrafish Proteins|Embryo, Nonmammalian|Gram Negative Bacteria|Fish Diseases|Immunity, Innate|ZNF365 protein, human|*DNA-Binding Proteins|*Transcription Factors|Amino Acid Sequence|Bacteria|Anti-Bacterial Agents 57 ZNF365 28205043 Breast Cancer Res. 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Sci. 2017 10.1167/iovs.17-22417 3 0 0 19 Humans|*Keratoconus|Australia|Genetic Predisposition to Disease|Brittle cornea syndrome 1|Skin Abnormalities|Polymorphism, Single Nucleotide|*Cohort Studies|Gene Frequency|Eye Abnormalities|Transcription Factors|Joint Instability|ZNF469 protein, human 49 ZNF469 29187250 BMC Res Notes 2017 PMC5707800 10.1186/s13104-017-2996-8 0 0 0 19 *Keratoconus|*Risk Factors|Saudi Arabia|*Cohort Studies|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Genotype|Transcription Factors|Polymerase Chain Reaction|Zinc Fingers 49 ZNF469 29111844 Ophthalmic Genet. 2017 10.1080/13816810.2017.1393831 5 0 0 19 Humans|*Keratoconus|Genome-Wide Association Study|Eye Proteins|Homeodomain Proteins|Mutations|Superoxide Dismutase-1|Polymorphism, Single Nucleotide|Frequencies, Allele|Superoxide Dismutase|MIRN184 microRNA, human|MicroRNAs 49 ZNF469 28966548 Mol. Vis. 2017 PMC5620381 0 0 0 19 Genome-Wide Association Study|*Endophenotypes|*Glaucoma, Primary Open Angle|Tonometry, Ocular|Intraocular Pressure|*Genetic Linkage|Optic Disk|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Norfolk Island 49 ZNF469 28676647 Sci Rep 2017 PMC5496893 10.1038/s41598-017-04393-2 6 2 0 19 Humans|*Keratoconus|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Cornea|Genotype|Case-Control Studies|Odds Ratio|Whites 49 ZNF469 28622062 Curr. Eye Res. 2017 10.1080/02713683.2017.1325910 4 0 0 19 Humans|*Keratoconus|Corneal Topography|Homeodomain Proteins|DNA Mutational Analysis|Transcription Factors|Polymorphism, Single Nucleotide|Corneal Transplantation|Mutation|Mutation, Missense|Zinc Fingers|ZNF469 protein, human 49 ZNF469 28484309 Mol. Vis. 2017 PMC5410165 2 0 0 19 Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Keratoconus|Transcription Factors 49 ZNF469 28453375 Ophthalmic Genet. 2017 10.1080/13816810.2017.1313993 4 0 0 19 Brittle cornea syndrome 1|Skin Abnormalities|Eye Abnormalities|Ehlers-Danlos Syndrome|DNA-Binding Proteins|Transcription Factors|*Complement Factor B|Keratoconus|Glaucoma, Primary Open Angle|Polymorphism, Single Nucleotide|Joint Instability|Mutation 49 ZNF598 28715909 Annu. Rev. Cell Dev. Biol. 2017 10.1146/annurev-cellbio-111315-125249 41 0 0 133 *Ribosome|Protein Biosynthesis|Ribosome Subunits, Large, Eukaryotic|Saccharomyces cerevisiae Proteins|Ubiquitination|Saccharomyces cerevisiae|E3 Ligase|Ubiquitin|tRNA|mRNA|Peptides 20 ZNF598 28685749 Nat Commun 2017 PMC5504347 10.1038/ncomms16056 33 16 0 133 Humans|*mRNA, Polyadenylated|*E3 Ubiquitin Ligase|*Ribosome|*RNA Binding Protein|Protein Biosynthesis|Ubiquitination|Ribosomal Proteins|Ubiquitin|tRNA|Polyadenylation|Carrier Proteins|HEK293 Cells|*Quality Control|ZNF598 protein, human 20 ZNF598 28132843 Mol. Cell 2017 PMC5321136 10.1016/j.molcel.2016.12.026 54 37 0 133 Animals|*Ribosome|ribosomal protein S20|Ribosomal Protein|*Ubiquitylation|Protein Biosynthesis|Ubiquitin|RACK1 Protein|mRNA|Carrier Proteins|Saccharomyces cerevisiae|Protein Binding|*Mammals|*Quality Control|RPS3 protein, S cerevisiae|Saccharomyces cerevisiae Proteins 20 ZNF598 28065601 Mol. Cell 2017 PMC5316413 10.1016/j.molcel.2016.11.039 55 15 0 133 Humans|Animals|*Poly A|*Ribosome|*Ubiquitination|Protein Biosynthesis|Ubiquitin|Ribosomal Proteins|Saccharomyces cerevisiae Proteins|Ubiquitin-Protein Ligases|Saccharomyces cerevisiae|RNA, Messenger|Carrier Proteins|HEK293 Cells|ZNF598 protein, human 20 ZNF644 28596979 Neurogenesis (Austin) 2017 PMC5449175 10.1080/23262133.2017.1316888 3 1 0 140 Histone-Lysine N-Methyltransferase|Histocompatibility Antigens|Histones|Transcription Factors|Methylation|Epigenesis, Genetic 20 ZNF91 29283313 RNA Biol 2017 PMC5798954 10.1080/15476286.2017.1409931 35 2 0 55 Humans|*RNA, Circular|*Cell Differentiation|miRNA|*Upregulation|Sequence Analysis, RNA|Gene Expression Profiling|*Stem Cells|Gene Regulatory Networks|RNA, Messenger|Gene Expression Regulation|High-Throughput Nucleotide Sequencing|*Transcriptional Activation|Binding Sites|*Epidermis|*Epidermal Cells|DHX9 protein, human|Neoplasm Proteins|DEAD-box RNA Helicases 26 ZPBP2 29126140 Mol. Hum. Reprod. 2017 PMC5909853 10.1093/molehr/gax053 0 0 0 22 Male|Humans|*Zona Pellucida|*Hyaluronic Acid|*Sperm|Sperm-Ovum Interactions|*Proteins|ZPBP2 protein, human|Egg Proteins|Membrane Proteins 39 ZPBP2 28588209 Sci Rep 2017 PMC5460198 10.1038/s41598-017-03067-3 0 1 0 22 Humans|Genome-Wide Association Study|*Liver Cirrhosis, Biliary|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Alleles|Genotype|Membrane Proteins|Neoplasm Proteins|Chromosomes, Human|ORMDL3 protein, human|GSDMB protein, human 39 ZPBP2 28461288 Eur. Respir. J. 2017 PMC5527708 10.1183/13993003.01505-2016 0 3 0 22 Humans|United States|*Genome-Wide Association Study|*Asthma|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Latino|Case-Control Studies|Mexican Americans|Puerto Rico 39 ZPBP2 28427360 BMC Med. Genet. 2017 PMC5399404 10.1186/s12881-017-0405-8 1 0 0 22 Humans|*Asian Continental Ancestry Group|*Lupus Erythematosus, Systemic|Single Nucleotide Polymorphisms|Gene Frequency|Genetic Predisposition to Disease|Alleles|Genetic Association Studies|Genotype|interferon regulatory factor-8|Interferon Regulatory Factors|Case-Control Studies|TMEM39A protein, human|Membrane Proteins 39 ZPBP2 28241063 PLoS ONE 2017 PMC5328393 10.1371/journal.pone.0172707 2 5 0 22 Humans|*DNA Methylation|Promoter Regions, Genetic|Alleles|Asthma|Genetic Predisposition to Disease|Membrane Proteins|Neoplasm Proteins|Polymorphism, Single Nucleotide|Egg Proteins|Genetic Variation|Base Sequence|*Cells, Epithelial|GSDMA protein, human|IKZF3 protein, human|Ikaros Transcription Factor 39 A2ML1 27942422 Curr Genet Med Rep 2016 PMC5142630 10.1007/s40142-016-0100-7 19 27 0 58 Humans|Noonan Syndrome|ras Proteins|Mitogen-Activated Protein Kinases|MAP Kinase Signaling System|Mutations, Germline|Phenotype|Signal Transduction 39 A4GALT 27538840 Glycoconj. 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Virol. 2016 PMC4984636 10.1128/JVI.00563-16 6 4 1 3025 Humans|Infant|Child|Mice|Animals|*Respiratory Syncytial Virus Infections|*Reactive Oxygen Species|*Lung Injury|Respiratory Syncytial Virus|Lung|Cells, Epithelial|Cytokines|Cell Line|IRG1 protein, human|Irg1 protein, mouse|Hydro-Lyases 24 ACOD1 26872335 PLoS ONE 2016 PMC4752512 10.1371/journal.pone.0149050 15 28 1 3025 Humans|Mice|Animals|IRF1 protein, human|*Interferon Regulatory Factor-1|*Gene Regulatory Networks|*Macrophages|*Gene Expression Regulation|Lipopolysaccharides|itaconic acid|Succinates|*Mammals|Hydro-Lyases|Proteins|Gene Expression|Cell Line|Carboxy-Lyases|Tricarboxylic Acid Cycle|siRNA|IRG1 protein, human|Irg1 protein, mouse 24 acrbp 27303034 Proc. Natl. Acad. Sci. 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Reprod. 2016 10.1095/biolreprod.115.134114 0 0 0 20 Male|Rats|Animals|*Epididymis|Sperm Maturation|*Sperm|*Glycopeptides|Testis|Glycoproteins|PNGase F|Proteomics|Chromatography, Liquid|Protein Processing, Post-Translational|TEX101 protein, rat|Membrane Glycoproteins 24 ADAMDEC1 27226416 J Crohns Colitis 2016 PMC5174729 10.1093/ecco-jcc/jjw111 7 10 1 24 Humans|Animals|decysin|*Disintegrins|Citrobacter rodentium|ADAM Proteins|Colitis|*Inflammation|Dextran Sulfate|*Intestines|Colon|Intestinal Mucosa|Enterobacteriaceae Infections|Macrophage|Disease Models, Animal 42 ADARB2 27376238 Nat. Genet. 2016 PMC4966644 10.1038/ng.3595 41 0 2 83 34 ADARB2 26929647 Onco Targets Ther 2016 PMC4758788 10.2147/OTT.S97664 32 3 2 83 34 ADARB2 26803156 Bioinformatics 2016 10.1093/bioinformatics/btw027 3 0 1 83 34 AFAP1L2 27835612 Oncotarget 2016 PMC5363521 10.18632/oncotarget.13261 2 62 0 160 Humans|*Cell Migration|Pseudopodia|WASL protein, human|Wiskott-Aldrich Syndrome Protein, Neuronal|Signal Transduction|Adaptor Proteins, Signal Transducing|Actins|Podosome|Cell Proliferation|Cells, Epithelial|Adaptor Proteins, Vesicular Transport 30 AFAP1L2 27509056 Oncotarget 2016 PMC5312318 10.18632/oncotarget.11074 4 15 0 160 Humans|Male|*Cellular Proliferation|*Cell Cycle|Adaptor Proteins, Signal Transducing|*Prostate Cancer|kallikrein-related peptidase 3, human|Prostate Specific Antigen|Signal Transduction|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Prognosis|Apoptosis|Biomarkers, Tumor|RNA, Small Interfering|Neoplasm Staging|Downregulation 30 AFAP1L2 26998266 Biomed Rep 2016 PMC4774376 10.3892/br.2016.588 2 0 0 160 Humans|Phosphatidylinositol 3-Kinases|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Adaptor Proteins, Signal Transducing|*Signal Transduction|Cell Proliferation|Cell Cycle|Proto-Oncogene Proteins c-akt|Microfilament Proteins|Cell Line, Tumor|Protein-Tyrosine Kinases|RNA, Small Interfering|mRNA|AFAP1L1 protein, human 30 AGAP1 27713690 Front Cell Neurosci 2016 PMC5031601 10.3389/fncel.2016.00218 4 10 1 202 *Dysbindin|*Dendritic Spines|Autism Spectrum Disorder|GTPase Activating Protein|ADP-Ribosylation Factor 1|Adaptor Protein Complex 3|Dystrophin-Associated Proteins|Endosomes|Protein Transport|Synapses|*Disorder, Neurodevelopmental|*Biological Transport 25 AGAP1 27531749 J. Biol. Chem. 2016 PMC5076806 10.1074/jbc.M116.732479 1 8 0 202 platelet protein P47|*Ankyrin Repeat|*Kinesin|*Phosphoproteins|*GTP Binding Protein|GTPase Activating Protein|*Blood Proteins|ADP-Ribosylation Factors|ADP-Ribosylation Factor 1|Carrier Proteins|Protein Binding|Adaptor Proteins, Signal Transducing|Cytoskeleton|Pleckstrin Homology Domains|Microtubules|Cell Line|Cell Movement 25 AJAP1 27870635 Biol Open 2016 PMC5155531 10.1242/bio.019463 1 5 0 135 Humans|Animals|Female|*Shrews|*Exon|Alternative Splicing|Lactation|Mammary Glands, Animal|RNA, Messenger|Epithelial Cells|Cell Nucleus|Cell Differentiation|Genes, Tumor Suppressor 58 AKTIP 27765929 Oncotarget 2016 PMC5363537 10.18632/oncotarget.12299 9 4 0 222 Humans|Female|*Uterine Cervical Neoplasms|Case-Control Studies|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Alleles|Genetic Association Studies|Genotype|MicroRNAs|Odds Ratio|Squamous Carcinomas|Risk Factors|MIRN17 microRNA, human 46 AKTIP 27535835 Cancer Chemother. Pharmacol. 2016 10.1007/s00280-016-3110-y 0 14 0 222 Humans|Female|*Cisplatin|*Uterine Cervical Neoplasms|*DNA Damage|*Cervix Uteri|STK36 protein, human|EGFR protein, human|Epidermal Growth Factor Receptor|*Protein Kinase Inhibitors|Apoptosis Regulatory Proteins|DNA-Dependent Protein Kinase|Adaptor Proteins, Signal Transducing|Cell Line, Tumor|HeLa Cells|RNA, Small Interfering|*Toes 46 AKTIP 27512140 Open Biol 2016 PMC5008010 10.1098/rsob.160103 9 26 1 222 lamin B1|*Lamin Type B|lamin C|Lamin A|*Telomeres|*Cellular Senescence|Nuclear Envelope|*Proteins|Mitosis|Spindle Apparatus|Telophase 46 AKTIP 27342216 J Pediatr (Rio J) 2016 10.1016/j.jped.2015.12.007 4 2 0 222 *Pediatric Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Overweight|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Body Mass Index|Genetic Association Studies|Alleles|Genotype|Insulin Resistance|Energy Intake 46 AKTIP 27073576 Oncol Lett 2016 PMC4812578 10.3892/ol.2016.4309 7 0 0 222 Humans|*Phosphatidylinositol 3-Kinases|*Phosphoinositide 3 Kinase|PTEN protein, human|PTEN Phosphohydrolase|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|*Cancers|Signal Transduction|CCND1 protein, human|Cyclin D1|Cell Transformation, Neoplastic|Mutation|Phosphorylation 46 AKTIP 27064284 J. Clin. Invest. 2016 PMC4855930 10.1172/JCI85526 28 1 1 222 Animals|Mice|Humans|Induced Pluripotent Stem Cells|*Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Adiposity|Transcription Factor|Hypothalamus|Leptin|SNPs|Intron|Homeodomain Proteins|Adipose Tissue|Gene Expression Regulation|Alleles|Adaptor Proteins, Signal Transducing|FTO protein, human|RPGRIP1L protein, human|FTO protein, mouse 46 AMIGO2 27378288 Bioinformatics 2016 PMC5079478 10.1093/bioinformatics/btw411 22 0 1 92 *Systems Biology|Software|Algorithms|Models, Biological|Metabolic Engineering 28 AMIGO2 27446084 Front Immunol 2016 PMC4922130 10.3389/fimmu.2016.00254 3 27 1 92 Humans|*Synoviocytes|IL17A protein, human|*Interleukin-17|Synovium|Rheumatoid Arthritis|Tumor Necrosis Factor-alpha|Osteoarthritis|*Apoptosis|Cytokines|Inflammation Mediators|Inflammation|Cells, Cultured|Fibroblasts 28 AMIGO2 27277807 J. 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Endocrinol. 2016 10.1080/09513590.2016.1203893 1 0 0 149 Female|Humans|*Polycystic Ovary Syndrome|Vascular Endothelial Growth Factor A|*Ovary|*Obesity|Body Mass Index|SERPINE1 protein, human|Plasminogen Activator Inhibitor 1|C-Reactive Protein|Insulin Resistance|Cardiovascular Diseases|Risk Factors|N,N-dimethylarginine|Arginine|ANGPTL6 protein, human|Angiopoietin-like Proteins 66 ANGPTL6 27181890 Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2016 10.3881/j.issn.1000-503X.2016.02.005 0 1 0 149 Humans|*Aortic Aneurysm, Abdominal|Angiopoietin-like Proteins|Case-Control Studies|Biomarkers|Angiopoietins|Enzyme-Linked Immunosorbent Assay|Risk Factors|Up-Regulation 66 ANKRD17 27526934 BMC Genomics 2016 PMC4986254 10.1186/s12864-016-2946-1 9 9 1 122 *Genes, Essential|Real Time PCR|Gene Expression Profiling|High-Throughput Nucleotide Sequencing 24 ANKRD17 27061206 Integr Zool 2016 10.1111/1749-4877.12199 2 0 0 122 Mice|Animals|Songbirds|Phenotypes|Animal Migration|Genomics|Alleles|Genotype 24 ANP32E 27569210 Cancer Res. 2016 10.1158/0008-5472.CAN-16-0500 11 0 0 183 Humans|*Methylation|Histone H3|Histone-Lysine N-Methyltransferase|*Protein Processing, Post-Translational|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Cell Cycle|Promoter Regions, Genetic|Lysine|*Cell Division|SMYD3 protein, human 36 ANP32E 26974126 Nat. 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Virol. 2016 PMC4836340 10.1128/JVI.03275-15 7 7 0 83 Mice|Animals|*HIV-1|vif protein, Human immunodeficiency virus 1|vif Gene Products, Human Immunodeficiency Virus|APOBEC-3G Deaminase|Cytosine Deaminase|Cytidine Deaminase|vif Gene|Virus Replication|*HIV Seropositivity|Amino Acid Sequence|Cell Line|DNA, Viral|Protein Binding|Apobec3 protein, mouse 32 ARL4C 27835592 Oncotarget 2016 PMC5348413 10.18632/oncotarget.13147 7 23 0 179 Humans|*DNA Methylation|*3' Untranslated Region|*Up-Regulation|5-hydroxymethylcytosine|5-Methylcytosine|*Cell Transformation, Neoplastic|*Tumorigenesis|*Carcinoma, Squamous Cell|*Epigenetic|Dioxygenases|Tongue Cancers|Proto-Oncogene Proteins|Epigenesis, Genetic|*Transcriptional Activation|Mixed Function Oxygenases|Gene Expression Regulation, Neoplastic|Squamous Cell Carcinoma of Head and Neck|*Carcinoma, Non-Small-Cell Lung 38 ARVCF 27685260 Sci Rep 2016 PMC5041581 10.1038/srep33439 10 1 1 78 Dogs|Humans|Animals|Adolescent|Genome-Wide Association Study|*Genome|*Genomics|Chromosome Mapping|Genotype|*Communication|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Domestication|Genetic Linkage|Breeding|Social Behaviors|Genetic Marker|Skills, Social 79 ARVCF 27614048 Protein Expr. Purif. 2016 10.1016/j.pep.2016.09.001 4 0 0 78 *Proteases|*Chromatography, Affinity|*Endopeptidases|Recombinant Fusion Proteins|Cloning, Molecular|Escherichia coli|Oligopeptides|Peptides 79 ARVCF 27411687 J Mammary Gland Biol Neoplasia 2016 PMC5159444 10.1007/s10911-016-9358-3 3 9 1 78 Humans|Mice|Animals|delta catenin|*Carcinoma, Lobular|*Catenins|CDH1 protein, human|E Cadherin|Anoikis|Mammary Neoplasms, Animal|Adherens Junction|Neoplasm Invasiveness|Antigens, CD|Cell Nucleus|Mice, Knockout|*Breast Neoplasms 79 ARVCF 27058532 Int J Mol Sci 2016 PMC4848957 10.3390/ijms17040501 3 0 1 78 Animals|*Quantitative Trait Loci|*Genome Mapping|*DNA Sequencing|Genetic Linkage|*Base Sequence|*Bass|Phenotype|Genotype|High-Throughput Nucleotide Sequencing|Single Nucleotide Polymorphisms|Perciformes 79 ARVCF 26887379 Mol. Neurobiol. 2016 10.1007/s12035-016-9752-2 2 1 0 78 *Hirschsprung Disease|*Exome|Genetic Predisposition to Disease|Genetic Loci|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Mutation|Exons 79 ASTN1 27826231 Front Behav Neurosci 2016 PMC5079073 10.3389/fnbeh.2016.00196 0 2 1 24 40 ASTN1 27650541 Oncotarget 2016 PMC5342012 10.18632/oncotarget.12063 10 3 0 24 Child|Humans|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|*RNA, Long Noncoding|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Oncogene Proteins, Fusion|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Transcriptome|B-Lymphocytes 40 ASTN1 27431290 Mol. Psychiatry 2016 10.1038/mp.2016.113 40 0 0 24 Humans|*Intellectual Disability|Exome|Genes, Recessive|Whole Exome Sequencing|Mutations|Homozygote|Genes, X-Linked|DNA Copy Number Variations|Sequence Analysis, DNA|Phenotypes|Genomics|Cohort Study|UBE4A protein, human|Ubiquitin-Protein Ligases|NUDT2 protein, human|Phosphoric Monoester Hydrolases 40 ASTN1 27042284 Mol Autism 2016 PMC4818446 10.1186/s13229-016-0079-7 9 2 1 24 Mice|Animals|*Parvalbumins|*Autistic Disorder|*Interneuron|*Memory|Hippocampus|Nerve Tissue Proteins|*ras Proteins|Disease Models, Animal|Cerebellum|BRINP1 protein, mouse 40 ASTN1 26786955 Cell Transplant 2016 10.3727/096368916X690520 8 2 0 24 Rats|Animals|*RNA, Micro|*Cell Proliferation|Schwann Cells|Nerve, Sciatic|Cell Movement|3' Untranslated Regions|Nerve Regeneration|Peripheral Nerve Injuries|Down-Regulation|Rats, Sprague-Dawley|Cells, Cultured|*Neurogenesis|ASTN1 protein, rat|Nerve Tissue Proteins|Receptors, Cell Surface|MIRNsc3 microRNA, rat 40 ASTN2 27854551 J. 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Cell Res. 2016 10.1016/j.yexcr.2016.09.015 0 0 0 95 Humans|Mice|Animals|*GTPases|Endoplasmic Reticulum|Golgi Apparatus|Saccharomyces cerevisiae|Hereditary Sensory Neuropathies|Membrane Proteins|*Mammals|*B Cells|HeLa Cells|ATL1 protein, human|GTP-Binding Proteins 23 ATL2 26965286 Breast Cancer Res. Treat. 2016 PMC4819548 10.1007/s10549-016-3741-z 23 1 1 95 Humans|*Transcriptome|Epithelial-Mesenchymal Transition|Gene Expression Profiling|Bone Neoplasms|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Up-Regulation|*Breast Cancer|Cohort Studies|MMS22L protein, human|DNA-Binding Proteins|Nuclear Proteins 23 ATRNL1 27706709 Genet. Mol. Res. 2016 10.4238/gmr.15038126 1 9 0 17 30 ATRNL1 27180803 Sci Rep 2016 PMC4867644 10.1038/srep26046 5 25 1 17 30 ATRNL1 27173231 Genet. Mol. Res. 2016 10.4238/gmr.15027191 3 10 0 17 30 BANK1 28011936 J. Immunol. 2016 PMC5557335 10.4049/jimmunol.1601157 11 0 0 136 Mice|Animals|*Mice, Inbred C57BL|MHC Class II Molecules|*Lymph Nodes|*Colitis|*Genes, MHC Class II|Dendritic Cells|Peptides|Mass Spectrometry|B Cells 86 BANK1 27816669 Clin. Immunol. 2016 PMC5148640 10.1016/j.clim.2016.10.018 5 11 0 136 Humans|*Lupus Erythematosus, Systemic|*B Cells|Genetic Predisposition to Disease|*Signal Transduction|Polymorphism, Single Nucleotide|Adaptor Proteins, Signal Transducing|Haplotype|Membrane Proteins|src-Family Kinases|Case-Control Studies|Genotype|Autoantibodies|BANK1 protein, human 86 BANK1 27671502 Int J Psychophysiol 2016 PMC5364069 10.1016/j.ijpsycho.2016.09.010 3 2 0 136 *Memory, Short-Term|*Genome-Wide Association Study|Reproducibility of Results|*Brain|Magnetic Resonance Imaging|Image Processing, Computer-Assisted|Oxygen|Polymorphism, Single Nucleotide|Neuropsychological Tests|Genotype 86 BANK1 27313329 Blood 2016 PMC5025901 10.1182/blood-2016-05-715342 6 0 0 136 Humans|*Graft vs Host Disease|*Risk Factors|Hematopoietic Stem Cell Transplantation|Unrelated Donors|Transplantation, Homologous|Haplotype|Histocompatibility Testing|Hematologic Neoplasms|Genotypes|Single Nucleotide Polymorphisms|Proportional Hazards Models|Cohort Study 86 BANK1 27228057 PLoS ONE 2016 PMC4882053 10.1371/journal.pone.0156302 10 61 1 136 Mice|Animals|*Toll-Like Receptor 7|STAT1 protein, human|*STAT1 Transcription Factor|Germinal Center|B Cells|Autoantibodies|Autoimmunity|Mice, Knockout|Plasma Cells|Phenotypes|Spleen|Membrane Glycoproteins|Signal Transduction|Gene Expression|Immunoglobulin G|Tlr7 protein, mouse|Stat1 protein, mouse|BANK1 protein, mouse 86 BARHL1 27310018 PLoS ONE 2016 PMC4911170 10.1371/journal.pone.0156907 3 2 1 73 Mice|Humans|Child|Animals|*Medulloblastoma|Hedgehog Proteins|Cerebellar Neoplasms|*Neurons|Cerebellum|*Cytoplasmic Granules|Genes, myc|*Disease Models, Animal|Stem Cells|Cells, Cultured|Signal Transduction|Cell Proliferation|Up-Regulation|Cell Growth Processes|Barhl1 protein, mouse|Nerve Tissue Proteins|Repressor Proteins 35 BARHL2 27887593 BMC Neurosci 2016 PMC5124293 10.1186/s12868-016-0311-6 3 6 0 57 Mice|Animals|*Prosencephalon|Paired Box Transcription Factors|Homeodomain Proteins|Eye Proteins|Repressor Proteins|*Embryo, Mammalian|Gene Expression Regulation, Developmental|PAX6 Transcription Factor|Body Patterning|Nerve Tissue Proteins|Thalamus|In Situ Hybridization|Neurogenesis|Barhl2 protein, mouse|Pax6 protein, mouse 30 BARHL2 27784329 Neural Dev 2016 PMC5081974 10.1186/s13064-016-0074-x 4 3 1 57 Humans|Infant, Newborn|DCC Receptor|*Neurogenesis|*Spinal Cord|Netrin-1|*Signal Transduction|Nerve Growth Factors|*Cell Movement|Axons|Tumor Suppressor Proteins|Receptors, Cell Surface|Interneurons|Neurons|DCC protein, human 30 BARHL2 27251161 In Vitro Cell. 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Neurobiol. 2016 PMC5191999 10.1007/s12035-016-0001-5 4 3 0 57 *Diencephalon|Body Patterning|Homeodomain Proteins|Thalamus|Hedgehog Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Homeobox Gene|Prosencephalon|Habenula|In Situ Hybridization 30 BARHL2 27150017 Sci Rep 2016 PMC4858678 10.1038/srep25667 7 34 1 57 Female|Mice|Animals|*Mouse Embryonic Stem Cells|*Transcription Factor|*Gene Expression Profiling|*Microarray Analysis|Cell Differentiation|Embryonic Stem Cells|Transcriptome|Gene Expression Regulation, Developmental|Cell Line|Mesoderm 30 BHLHA15 27881402 Am. J. Physiol. Gastrointest. Liver Physiol. 2016 PMC5283902 10.1152/ajpgi.00326.2016 9 1 0 200 *Metaplasia|Chief Cells, Gastric|Parietal Cells, Gastric|TFF2 protein, human|Trefoil Factor-2|Gastric Mucosa|*Cell Transdifferentiation|Stomach Neoplasms|spasmolytic polypeptide|Peptides|Precancerous Conditions|Cell Lineage|Intercellular Signaling Peptides and Proteins|Cell Transformation, Neoplastic|*Epithelial Cells 66 BHLHA15 27644325 Mol. Cell. Biol. 2016 PMC5108881 10.1128/MCB.00366-16 9 1 0 200 *Unfolded Protein Response|Transcription Factor|X-Box Binding Protein 1|Endoplasmic Reticulum Stress|Gene Expression Regulation|Endoplasmic Reticulum|Basic Helix-Loop-Helix Transcription Factors|Transcriptional Networks|Regulatory Factor X Transcription Factors|Cell Differentiation|Promoter Regions, Genetic 66 BHLHA15 27340127 Am. J. Physiol. Gastrointest. 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Cancer Res. 2016 10.1158/1078-0432.CCR-15-2903 11 0 0 204 fludarabine|*Leukemia, Lymphocytic, Chronic, B-Cell|*Vidarabine|Drug Resistance, Neoplasm|Tumor Suppressor Protein p53|Antineoplastic Agents|Cell Cycle Proteins|Protein-Serine-Threonine Kinases|Apoptosis|Tumor Cells, Cultured|*Mutagenesis 23 BMP2K 26853940 Structure 2016 PMC4780864 10.1016/j.str.2015.12.015 28 20 1 204 Humans|Numb protein, human|*Membrane Proteins|*Nerve Tissue Proteins|Protein-Serine-Threonine Kinases|Protein Conformation|Amino Acid Sequence|Binding Sites|Models, Molecular|Endocytosis 23 BRAC1 27459855 Breast Cancer Res. 2016 PMC4962376 10.1186/s13058-016-0718-0 10 2 1 0 Genome-Wide Association Study|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Chromosome Mapping|Genetic Loci|Alleles|*Risk|Case-Control Studies|Genotype 40 BRAC1 27325824 Acta Biochim. Biophys. Sin. (Shanghai) 2016 10.1093/abbs/gmw047 7 1 0 0 Humans|BRCA1 protein, human|*Breast Cancer Type 1 Susceptibility Protein|*DNA Damage|DNA Repair|Nuclear Proteins|Carrier Proteins|DNA-Binding Proteins|Histone Chaperones|Adaptor Proteins, Signal Transducing|Breast Cancer, Familial|Breast Neoplasms|Deubiquitinating Enzymes|3'-(1-butylphosphoryl)adenosine|Cell Line, Tumor 40 BRAC1 26740498 J. Int. Med. Res. 2016 PMC5536563 10.1177/0300060515607383 0 5 0 0 Humans|*Nonsmall Cell Lung Cancer|*Proto-Oncogene Proteins p21(ras)|*Platinum|Lung Neoplasms|Retrospective Studies|*Mutation|ErbB Receptors|BRCA1 protein, human|BRCA1 Protein|Antineoplastic Combined Chemotherapy Protocols|Adenocarcinoma|Prognosis|Biomarkers, Tumor|Cohort Studies|KRAS protein, human|TYMS protein, human|Thymidylate Synthase 40 BRSK1 27677186 Oncology 2016 10.1159/000450616 5 0 0 135 *Colorectal Cancers|*Tumor Suppressor Genes|Microsatellite Instability|Gastric Cancers|Frameshift Mutation|*Stomach|DNA, Neoplasm|DNA Mutational Analysis 48 BRSK1 27626661 Cell Rep 2016 10.1016/j.celrep.2016.08.020 5 5 0 135 *Phosphorylation|*Depression|Synaptic Vesicles|Synaptic Transmission|Synapses|Presynaptic Terminals|Neurons|Hippocampus|Cytoskeletal Proteins|Cells, Cultured 48 BRSK1 27251228 Biosci. Biotechnol. Biochem. 2016 10.1080/09168451.2016.1191331 0 0 0 135 Mice|Animals|Amino Acid Sequence|Protein-Serine-Threonine Kinases|Crystallography, X-Ray|Sequence Homology, Amino Acid|Models, Molecular|Catalytic Domain|Protein Domains|*Inhibition, Psychological|Synapses 48 BRSK1 27154488 Neuroscientist 2016 10.1177/1073858416648307 3 4 0 135 Animals|*Axonal Transport|Caenorhabditis elegans|*Neurons|Caenorhabditis elegans Proteins|Axons|Dynein|Lysosomes|Nerve Tissue Proteins|CDK5 protein, human|Cyclin-Dependent Kinase 5|Adaptor Proteins, Signal Transducing|Synapses|Endosomes|Transport Vesicles|Golgi Apparatus 48 BRWD3 27588417 PLoS Genet. 2016 PMC5010193 10.1371/journal.pgen.1006262 1 62 1 50 Animals|*Ectopic Gene Expression|*Polycomb-Group Proteins|Chromatin|Drosophila Proteins|Drosophila melanogaster|Histone H3.3|DNA-Binding Proteins|Transcription Factors|Gene Expression Regulation, Developmental|*Mutations|Epigenesis, Genetic|Hira protein, Drosophila|Cell Cycle Proteins|Histone Chaperones 25 BRWD3 26741981 PLoS ONE 2016 PMC4704813 10.1371/journal.pone.0146571 2 33 1 50 Animals|*Cryptochromes|*Drosophila|*Circadian Clocks|*Glycogen Synthase Kinase 3|Drosophila Proteins|Drosophila melanogaster|Photoreceptor Cells, Invertebrate|Circadian Rhythm|Eye Proteins|Light|*Glycogen Synthase Kinase 3 beta|E3 Ubiquitin Ligase|Neurons|timeless protein, Drosophila 25 BTG4 27993988 Development 2016 10.1242/dev.144410 17 0 0 17 Mice|Animals|*RNA, Messenger, Stored|*MAP Kinase Signaling System|*Oocytes|Oogenesis|mRNA Cleavage and Polyadenylation Factors|Meiosis|RNA-Binding Proteins|RNA, Messenger|Zygotes|Protein Biosynthesis|Transcription Factors|Phosphorylation|Cpeb1 protein, mouse 40 BTG4 27605379 Open Biol 2016 PMC5043581 10.1098/rsob.160184 8 14 1 17 Female|Animals|*mRNA, Maternal|Meiosis|Metaphase|Anaphase-Promoting Complex-Cyclosome|Oocytes|Anaphase|Cell Cycle Proteins|Xenopus Proteins|F-Box Proteins|Embryo, Mammalian|mRNA 40 BTG4 27065194 Nat. 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Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.05.013 1 8 0 110 Humans|*Fibroblast Growth Factor 1|SMAD3 protein, human|Smad3 Protein|Fibroblasts|Transforming Growth Factor beta1|Smad2 Protein|Fibrosis|Extracellular Matrix|Signal Transduction|Collagen Type I|Phosphorylation|Cells, Cultured|Actins|Cell Proliferation 33 C2CD4B 27329800 Am. J. Physiol. Endocrinol. Metab. 2016 PMC5005967 10.1152/ajpendo.00074.2016 5 10 1 16 Male|Female|Mice|Humans|Animals|*Glucose Intolerance|*Diabetes Mellitus, Type 2|Insulin Secretion|Insulin-Secreting Cells|Insulin|Glucagon|Islets of Langerhans|Glucose|Mice, Knockout|Pancreas|Single Nucleotide Polymorphisms|VPS13C protein, human|Proteins 24 CAMK1D 27285980 Oncotarget 2016 PMC5226485 10.18632/oncotarget.9832 3 49 1 112 Mice|Animals|*Neuraminidase|Influenza A Virus, H9N2 Subtype|*Downregulation|Dendritic Cells|MicroRNAs|Mice, Inbred C57BL|Up-Regulation|Lymphocyte Activation|Signal Transduction|MBNL3 protein, mouse|Carrier Proteins|MIRN674 microRNA, mouse 60 CAMK1D 27281091 Medicine (Baltimore) 2016 PMC4907669 10.1097/MD.0000000000003841 7 3 1 112 Humans|*Diabetes Mellitus, Type 2|*Case-Control Studies|Genome-Wide Association Study|*Chinese|Single Nucleotide Polymorphisms|Transcription Factor 7-Like 2 Protein|Genotype|Genetic Predisposition to Disease|Body Mass Index|Blood Glucose|Genetic Loci|Alleles|Obesity|Oral Glucose Tolerance Test|Risk Factors|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 60 CARD6 27911816 Proc. 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U.S.A. 2016 PMC5167174 10.1073/pnas.1614898113 16 0 0 74 *Glioblastoma|*Microfluidics|adriamycinol|*Doxorubicin|Brain Neoplasms|Drug Resistance, Neoplasm|Cell Line, Tumor|Aldo-Keto Reductase|NF-kappa B|Signal Transduction|Apoptosis 30 CARD6 27018246 Photodiagnosis Photodyn Ther 2016 10.1016/j.pdpdt.2016.03.006 0 2 0 74 Animals|*Photochemotherapy|Photosensitizing Agents|Porphyrins|*Disease Models, Animal|Apoptosis|Cell Line, Tumor 30 CARD6 26976200 Sci Rep 2016 PMC4792137 10.1038/srep22745 20 4 1 74 *Inflammasomes|*Epidermis|*Epidermal Cells|Keratinocytes|Psoriasis|Skin|*Signal Transduction|*Carrier Proteins|mRNA|Upregulation|Gene Expression Regulation|Gene Expression|Cells, Cultured|NLR Proteins 30 CARTPT 27805868 Endocrinology 2016 10.1210/en.2016-1516 5 0 0 1118 Humans|Female|Rats|Animals|Infant|*Hippocampal Formation|*Ovariectomy|Estrogens|Estradiol|Transcriptome Analysis|Menopause|Gene Expression Regulation|cocaine- and amphetamine-regulated transcript protein|Nerve Tissue Proteins|Oligonucleotide Array Sequence Analysis|Synaptic Plasticity|Neurotransmission|Transcriptome|Memory|NGFR protein, human|IGF2 protein, human|IGF-2|Receptors, Nerve Growth Factor 39 CARTPT 27354525 Proc. Natl. Acad. Sci. U.S.A. 2016 PMC4948346 10.1073/pnas.1603111113 20 0 0 1118 Humans|Rats|Animals|*Antidepressants|*Hippocampus|metabotropic glutamate receptor 2|Receptors, Metabotropic Glutamate|*Epigenesis, Genetic|Depression|Acetyl L Carnitine|Stress, Psychological|Glutamate|Neuropeptide Y|Behavior, Animal|cocaine- and amphetamine-regulated transcript protein|Nerve Tissue Proteins|*Epigenetics 39 CARTPT 27338624 Diabetologia 2016 10.1007/s00125-016-4020-6 4 5 0 1118 Humans|Rats|Mice|Animals|*Insulin Secretion|*Glucagon|cocaine- and amphetamine-regulated transcript protein|Diabetes Mellitus, Type 2|*Nerve Tissue Proteins|Insulin-Secreting Cells|B-insulin|Insulin|Islets of Langerhans|Glucagon-Secreting Cells|Glucose|Biotin 39 CCDC170 27372070 Breast Cancer Res. Treat. 2016 PMC4979600 10.1007/s10549-016-3876-y 8 7 0 50 22 CCDC170 26928228 Nat. Genet. 2016 PMC4938803 10.1038/ng.3521 42 11 1 50 Humans|Estrogen Receptor alpha|Genetic Predisposition to Disease|Density, Mammographic|Polymorphism, Single Nucleotide|Alleles|Genome-Wide Association Study|Genotype|*Risk|Phenotype|Case-Control Studies|Cell Line, Tumor|*Genes, Regulator|Carrier Proteins|ERBB2 protein, human|Receptor, ErbB-2|RMND1 protein, human|Cell Cycle Proteins|CCDC170 protein, human 22 CCDC170 26911590 BMC Genomics 2016 PMC4766752 10.1186/s12864-016-2481-0 11 1 1 50 *Bone Density|*Genome-Wide Association Study|Osteoporosis|Femur Neck|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Fractures, Bone|Genotype|Lumbar Vertebrae|Estrogen Receptor alpha|Phenotype 22 CDC42EP4 27913681 Biochem. Soc. Trans. 2016 PMC5134998 10.1042/BST20160219 5 22 0 127 cdc42 Protein|rho GTPases|GTP-Binding Protein Regulators|Cytoskeleton|Signal Transduction|Cell Shape 20 CDH16 27780871 J. Cell. Sci. 2016 PMC5394772 10.1242/jcs.184291 6 13 0 53 Rats|Mice|Animals|*Thyroid Gland|PAX8 protein, human|*PAX8 Transcription Factor|Thyrotropin|Cell Polarity|Laminin|Thyrocytes|Morphogenesis|Cells, Cultured|Cells, Epithelial|Cadherins|Cell Line|Rats, Inbred F344|RNA Interference|Cytoskeleton|Pax8 protein, mouse 48 CDH16 26980015 Hum. Pathol. 2016 10.1016/j.humpath.2016.01.004 2 0 0 53 Humans|Papillary renal cell carcinoma, sporadic|*Carcinoma, Renal Cell|Kidney Neoplasms|Birt-Hogg-Dube Syndrome|Germline Mutation|Tumor Suppressor Proteins|Proto-Oncogene Proteins|Mutation|Genetic Testing|*In Situ Hybridization|FLCN protein, human 48 CDH16 26913567 J. Pathol. 2016 10.1002/path.4706 5 1 0 53 Mice|Animals|YAP1 (Yes-associated) protein, human|Phosphoproteins|Adaptor Proteins, Signal Transducing|*Kidney|Cell Cycle Proteins|Protein-Serine-Threonine Kinases|Signal Transduction|Transcription Factors|Kidney Tubules|Clear Cell Renal Cell Carcinoma|Cell Proliferation|Downregulation|*Epithelium|Cells, Epithelial|Kidney Neoplasms|Sav1 protein, mouse 48 CDH16 26756467 Horm. Metab. Res. 2016 10.1055/s-0035-1569289 2 0 0 53 *Thyroid Cancer, Papillary|Carcinoma, Thyroid|Carcinoma, Papillary|Gene Expression Profiling|Gene Expression Profiles|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Carcinoma|Computational Biology|Downregulation|Disease Progression 48 CDH19 27303947 Exp. Dermatol. 2016 10.1111/exd.13110 2 0 0 36 Humans|Adult|*Cell Dedifferentiation|Neurofibroma|*Schwann Cells|Neurofibromatosis 1 25 CDH19 26909693 PLoS ONE 2016 PMC4766096 10.1371/journal.pone.0148679 3 0 1 36 Humans|*Music|*Genetic Linkage|Aptitude|Creativity|Chromosome Mapping|Phenotype|Cognitive Function 25 CDHR1 27623334 Invest. Ophthalmol. Vis. Sci. 2016 10.1167/iovs.16-19687 6 0 0 33 *Alleles|*Retinal Dystrophy|Electroretinography|Homozygote|DNA Mutational Analysis|Fluorescein Angiography|Genes, Recessive|Retina|Mutation|Pedigree|Visual Fields|*Mutation, Activation|Tomography, Optical Coherence|Visual Acuity|Phenotype|Nerve Tissue Proteins 34 CDHR1 27391102 PLoS ONE 2016 PMC4938416 10.1371/journal.pone.0158692 6 3 1 33 Humans|*Whole Exome Sequencing|*Retinal Dystrophies|Exome|DNA Mutational Analysis|Pedigree|Mutation|Eye Proteins|Sequence Analysis, DNA|PRPF31 protein, human|BEST1 protein, human|Bestrophins 34 CDHR1 26998897 Cancer 2016 10.1002/cncr.29974 5 0 0 33 Humans|*Whole Exome Sequencing|*Wnt Signaling Pathway|*Adenocarcinoma|*Duodenal Neoplasms|*Mutations|DNA Mutational Analysis|beta Catenin|*Catenins|Jejunal Neoplasms|Ileal Neoplasms 34 CDHR1 26986842 PLoS ONE 2016 PMC4795703 10.1371/journal.pone.0151927 6 15 1 33 Mice|Animals|*Insulin Secretion|Insulin|Insulin-Secreting Cells|*Cell Line|Glucose|*Pancreas|Cells, Cultured|Insulin, Regular, Human|Tmem59l protein, mouse|Membrane Proteins|Celsr2 protein, mouse|Cadherins 34 CDHR1 26957898 Mol. Vis. 2016 PMC4764614 13 5 0 33 Humans|*Cone-Rod Dystrophies|Japan|*Retinitis Pigmentosa|*Sequencing, Next-Generation|*Retinal Cone Photoreceptor Cells|DNA Mutational Analysis|Eye Proteins|Exome|Pedigree|Mutations|Phenotype 34 CDHR1 26948891 Neuron 2016 PMC4795965 10.1016/j.neuron.2016.02.004 37 0 2 33 Mice|Animals|*Neurons|Olfactory Bulb|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Embryo, Mammalian|Cell Movement|Cells, Cultured|Animals, Newborn|Cloning, Molecular 34 CDK2AP2 27770808 J Ovarian Res 2016 PMC5075411 10.1186/s13048-016-0275-2 3 11 1 664 Humans|Female|*Malignant Epithelial Tumors|Ovarian Neoplasms|Cyclin-Dependent Kinase Inhibitor p16|Immunohistochemistry|*Ovary|Tumor Suppressor Protein p53|Prognosis|Biomarkers, Tumor 32 CDK2AP2 27720643 Mol. Cell 2016 10.1016/j.molcel.2016.08.036 56 16 0 664 Humans|Ribonucleoprotein, U2 Small Nuclear|RNA Splicing Factors|RNA Splicing|Spliceosomes|Splicing Factor U2AF|RNA Precursors|Binding Site|Protein Conformation|Ribonucleoproteins|Phosphoproteins|Protein Binding|Amino Acid Sequence|Models, Molecular|Nuclear Proteins|Binding Proteins|*Mutations 32 CDK2AP2 27465101 BMC Cancer 2016 PMC4963937 10.1186/s12885-016-2514-8 5 14 1 664 Humans|*Carcinoma, Renal Cell|Renal Cancer|*Microsatellite|Loss of Heterozygosity|Cyclin-Dependent Kinase Inhibitor p15|Genes, Tumor Suppressor|Cyclin-Dependent Kinase Inhibitor p16|Tumor Suppressor Proteins|Prognosis|Chromosomes 32 CDK2AP2 27401842 Gynecol. Oncol. 2016 PMC5125392 10.1016/j.ygyno.2016.07.006 14 5 0 664 Humans|Female|*Cervical Intraepithelial Neoplasia|Cervical Cancer|Cyclin-Dependent Kinase Inhibitor p16|DNA Methylation|Papillomavirus Infections|*Epigenesis, Genetic|Promoter Regions, Genetic|*Disease Progression|Tumor Suppressor Proteins|*Cyclin-Dependent Kinase Inhibitor Proteins 32 CDK2AP2 27302160 Cancer Res. 2016 10.1158/0008-5472.CAN-15-1025 3 2 0 664 Humans|Mice|Animals|*p14(ARF)|*Lung Cancers|Non-Small-Cell Lung Carcinomas|Small Cell Lung Carcinoma|Cell Line, Tumor|Cell Transformation, Neoplastic|Nuclear Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Exons|Carcinogenesis|*Neoplastic Processes|Lung|*Cyclin-Dependent Kinase Inhibitor p16|AIMP2 protein, human 32 CDK2AP2 27276112 Int. J. Gynecol. Pathol. 2016 10.1097/PGP.0000000000000181 1 1 0 664 Humans|Female|*Genes, p16|*Methylation|*Cell Transdifferentiation|Leiomyosarcoma|Uterine Neoplasms|Cyclin-Dependent Kinase Inhibitor p16|*Myosarcomas|Rhabdomyosarcoma|Immunohistochemistry|*Promoter Regions, Genetic|Soft Tissue Neoplasms|Tumor Suppressor Protein p53|*Uterus|*Muscle Neoplasms|Rhabdomyosarcoma, Embryonal|Epigenesis, Genetic 32 CDKL2 27760737 Brief. Bioinformatics 2016 10.1093/bib/bbw094 12 0 0 100 Humans|*Carcinoma, Hepatocellular|*DNA Methylation|*Liver Neoplasms|*B-DNA|CpG Islands|Promoter Regions, Genetic|Epigenesis, Genetic|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Epigenetic|Phenotype|Cell Line, Tumor 20 CDKL2 26982032 PLoS Biol. 2016 PMC4794247 10.1371/journal.pbio.1002416 31 19 1 100 Animals|Humans|*Cilia|Proteomics|Meckel syndrome type 1|Ciliary Motility Disorders|Meckel Syndrome, Type 4|Polycystic Kidney Diseases|Caenorhabditis elegans|Encephalocele|Caenorhabditis elegans Proteins|Retinitis Pigmentosa|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|Proteins, Membrane-Associated|Protein Transport|Liver|Polydactyly|Cep290 protein, human|Antigens, Neoplasm 20 CDKL2 26902887 Genomics 2016 PMC4992660 10.1016/j.ygeno.2016.02.004 8 2 0 100 Humans|Male|*DNA Methylation|*African Americans|Neoplasm Recurrence, Local|Prostate Cancer, Hereditary, 7|*Prostate Cancer|Prostatectomy|CpG Islands|Prostate|*Disease Progression|Epigenomics|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|cytidylyl-3'-5'-guanosine|Dinucleoside Phosphates 20 CDY1 27725957 ACS Cent Sci 2016 PMC5043430 10.1021/acscentsci.6b00099 4 9 1 6 Mice|Animals|Endothelial Cells|*Pluripotent Stem Cell|*Teratoma|*Stem Cell Transplantation|Cell Differentiation|*Light, Visible|Cells, Cultured|Reactive Oxygen Species 54 CDY1 27525321 Int J Reprod Biomed (Yazd) 2016 PMC4971549 2 3 0 6 Humans|Male|*Azoospermia|Testicular Sperm Retrieval|*Sperm|Testis|*Biomarkers 54 CDY1 27457284 Gene 2016 10.1016/j.gene.2016.07.050 1 0 0 6 Humans|Male|*Risk Factors|Semen Analysis|Deleted in Azoospermia 1 Protein|*Infertility, Male|Azoospermia|Oligospermia|Spermatogenesis|Chromosomes, Human, Y|Gene Deletion|RNA-Binding Proteins|Sequence Tagged Site|Gene Dosage|Nuclear Proteins|Case-Control Studies|Tunisia|DAZ2 protein, human|DAZ4 protein, human 54 CDY1 26995389 J. 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Chem. 2016 10.1021/acs.jmedchem.6b00264 18 0 0 63 *Nuclear Proteins|*Transcription Factors|*Water|*Protein Domains|*Molecular Conformation|Molecular Structure|Structure-Activity Relationship|Cell Cycle Proteins|Crystallography, X-Ray|6-methyl pyrrolopyridone|Pyrroles|Cell Line, Tumor|Models, Molecular|Pyridones|Ligands 32 CECR2 26989192 Dis Model Mech 2016 PMC4892663 10.1242/dmm.024109 6 11 1 63 Humans|Mice|Animals|*Neural Tube|*Neurulation|Neural Tube Defects|*Mutation|Wnt Signaling Pathway|Transcription Factors|Wnt Proteins|Cell Polarity|Gene Expression Regulation, Developmental|Embryo, Mammalian|Craniofacial Abnormalities|Cephalocele|TET1 protein, human|Mixed Function Oxygenases|Proto-Oncogene Proteins|GRHL2 protein, human|DNA-Binding Proteins|Cecr2 protein, human 32 CELF4 27507616 Clin. Cancer Res. 2016 10.1158/1078-0432.CCR-16-0863 13 0 0 34 Humans|Female|*Epigenomics|*DNA Methylation|*Endometrial Cancer|*Cervix Uteri|Cervical Intraepithelial Neoplasia|CpG Islands|Uterine Cervical Neoplasms|Early Detection of Cancer|Biomarkers, Tumor|*Endometrium|ROC Curve|Case-Control Studies 43 CELF4 27467452 Int J Speech Lang Pathol 2016 10.1080/17549507.2016.1209559 1 0 0 34 Child|Humans|Child, Preschool|Australia|*Language|Language Development Disorders|Health Care Costs|Cohort Studies 43 CELF4 27067015 Mol. Psychiatry 2016 PMC4879189 10.1038/mp.2016.49 48 1 0 34 Humans|*Neuroticism|Genome-Wide Association Study|Depressive Disorder, Major|Multifactorial Inheritance|Single Nucleotide Polymorphism|Bipolar Disorder|Genetic Predisposition to Disease|Schizophrenia|Phenotypes|Cohort Studies|Risk Factors|Scotland|Family Member|Queensland 43 CELF4 27064787 PLoS ONE 2016 PMC4827826 10.1371/journal.pone.0153444 3 21 1 34 Humans|*Salmonella typhimurium|*Caco-2 Cells|*Transcriptome|*Serogroup|Salmonella Infections|Gene Expression Regulation, Bacterial|Intestines|Cells, Epithelial|Bacterial Proteins|Virulence|Membrane Protein|*Epithelium|Upregulation 43 CELF4 26968791 Biol. Blood Marrow Transplant. 2016 PMC4977273 10.1016/j.bbmt.2016.02.017 5 0 0 34 Humans|*Hematopoietic Stem Cell Transplantation|*Survivors|*Cardiomyopathy|Risk Factors|Hypertension|Anthracyclines|Cardiovascular Diseases|Odds Ratios|Diabetes Mellitus|Case-Control Studies|Cohort Studies 43 CELF4 26811534 J. Clin. Oncol. 2016 PMC5070560 10.1200/JCO.2015.63.4550 18 0 0 34 Child|Humans|*Genome-Wide Association Study|*Anthracyclines|*Cardiomyopathy|*Antibiotics, Antineoplastic|Genetic Susceptibility|Polymorphism, Single Nucleotide|Survivors|Case-Control Studies|Risk Factors|CELF4 protein, human|CELF Proteins 43 cenpb 27658157 Clin. Chem. Lab. Med. 2016 10.1515/cclm-2016-0533 0 0 0 198 Humans|*Autoantibodies|Antibodies, Antinuclear|Fluorescent Antibody Technique, Indirect|Immunoassay|Enzyme-Linked Immunosorbent Assay|Sensitivity and Specificity 183 cenpb 27384170 Genome Res. 2016 PMC5052034 10.1101/gr.204784.116 10 1 0 198 Humans|*Nucleosomes|centromere protein C|Chromosomal Proteins, Non-Histone|Centromere|Centromere Protein A|Kinetochore|Chromatin|Histone|DNA, Satellite|Autoantigens|*Cell Cycle Proteins|HeLa Cells|CENPT protein, human 183 cenpb 27159521 2016 PMC5042822 10.1002/art.39743 3 1 0 198 Humans|*Autoantigens|Centromere Protein B|Autoantibodies|Centromere Protein A|Chromosomal Proteins, Non-Histone|*Disease, Vascular|Enzyme-Linked Immunosorbent Assay|*Scleroderma, Localized 183 cenpb 27059145 2016 PMC5042816 10.1002/art.39706 22 12 1 198 Humans|Female|*Autoimmunity|*Autoantibodies|Antinuclear Antibodies|Lupus Erythematosus, Systemic|Cytokines|Interferon-alpha 183 CES1P1 27228223 Basic Clin. Pharmacol. Toxicol. 2016 PMC5118077 10.1111/bcpt.12625 9 3 0 5 Male|Humans|Female|oseltamivir carboxylate|*Oseltamivir|Antiviral Agents|Carboxylic Ester Hydrolases|Genotype|Orthomyxoviridae|Prodrugs|Polymorphism, Single Nucleotide|Livers|Pharmacogenetics 20 CES1P1 26915813 Eur. J. Clin. Pharmacol. 2016 PMC4865408 10.1007/s00228-016-2029-x 3 2 0 5 Humans|*Antihypertensive Agents|trandolapril|*Indoles|Angiotensin-Converting Enzyme Inhibitors|Carboxylesterase|*Livers|Carboxylic Ester Hydrolases|Genotype|Hypertension|Prodrugs|Polymorphism, Single Nucleotide|CES1P1 protein, human 20 CES1P1 26871237 Pharmacogenet. Genomics 2016 PMC4821783 10.1097/FPC.0000000000000206 4 6 0 5 Humans|CES1 protein, human|*Carboxylic Ester Hydrolases|*Genomics|Liver|Polymorphism, Single Nucleotide|*Translocation, Genetic 20 CFDP1 27151176 Sci Rep 2016 PMC4858687 10.1038/srep25511 2 4 1 43 Animals|Humans|*Drosophila|Drosophila melanogaster|CFDP1 protein, human|Phosphoproteins|Chromatin|Amino Acid Sequence|*Biological Evolution|Ruminants|Yeti protein, Drosophila|Carrier Proteins|Drosophila Proteins 40 CFDP1 26925320 PeerJ 2016 PMC4768678 10.7717/peerj.1682 0 0 1 43 Animals|Dogs|Humans|*Pituitary-Adrenal System|Hypothalamo-Hypophyseal System|Pituitary Gland|Transcriptome|Adrenal Cortex|High-Throughput Nucleotide Sequencing|Gene Expression Profiling|Gene Regulatory Networks|Hippocampus|MicroRNAs|Gene Expression Regulation, Developmental|*Chinese|Upregulation 40 CHD6 27748065 Am. J. Med. Genet. 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Virol. 2016 PMC4794673 10.1128/JVI.00053-16 10 5 2 261 Mice|Animals|*Chromatin|*Influenzavirus B|*Chromatin Assembly and Disassembly|*Influenza B virus|Influenza A virus|histone H3 trimethyl Lys4|Histone|RNA Polymerase II|Virus Replication|Orthomyxoviridae Infections|Influenza|Orthomyxoviridae|Viral Proteins|RNA, Viral|Host-Pathogen Interactions|Chd6 protein, mouse|DNA Helicases 31 CHI3L2 27794455 Virus Res. 2016 10.1016/j.virusres.2016.10.012 0 0 0 30 Animals|Humans|*Simian Immunodeficiency Virus|*Chitinases|*AIDS Dementia Complex|Simian Acquired Immunodeficiency Syndrome|*Encephalitis|HIV Infection|Macaca mulatta|Encephalitis, Viral|HIV-1|Brain|Neurocognitive Disorder|Macrophages 35 CHI3L2 27653898 J. Neurol. Sci. 2016 10.1016/j.jns.2016.08.029 5 2 0 30 Humans|*Alzheimer Disease|*Chitinase|*Brain|Hexosaminidases 35 CHI3L2 26872061 Eur. J. Neurol. 2016 10.1111/ene.12960 9 0 0 30 chitotriosidase|*Multiple Sclerosis|*Chitinase|*Prognosis|*Hexosaminidases|Neuritis, Optic|Neurofilament Proteins|Adipokines|Lectins|Biomarkers|Disease Progression 35 CHI3L2 26733160 Biol. Chem. 2016 10.1515/hsz-2015-0269 0 8 0 30 Humans|Male|Animals|*Chitinase|Endothelial Cells|Lectins|Adipokines|*Cancers|Tumor Microenvironment|Neovascularization, Pathologic|Cytokines|Macrophages|Anti-Inflammatory Agents|Cell Proliferation|CHI3L1 protein, human|Chitinase-3-Like Protein 1|ERK1-2 Pathway|Inflammation 35 CHRFAM7A 27051591 BBA Clin 2016 PMC4802402 10.1016/j.bbacli.2015.12.003 4 0 1 87 Humans|*Up-Regulation|alpha7 Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptor|*Inflammatory Bowel Disease 57 CHRFAM7A 26997942 Mol Syndromol 2016 PMC4772713 10.1159/000443343 4 0 0 87 Humans|Chromosome 15q13.3 Microdeletion Syndrome|*Chromosomes, Human, Pair 15|*Chromosome Deletion|*Chromosome Disorders|*Intellectual Disability|*Seizures|Segmental Duplications|Comparative Genomic Hybridization|Pedigree|Heterozygote|alpha7 Nicotinic Acetylcholine Receptor 57 CILP2 27031336 PLoS ONE 2016 PMC4816345 10.1371/journal.pone.0152708 2 1 1 28 Humans|Male|Rats|Animals|*Metabolic Syndrome|*Chromosome 16|Spontaneously Hypertensive Rats|Rats, Inbred BN|Animals, Congenic|*Genomes|*Genomics|Blood Pressure|Triglycerides|Hypertension|Cholesterol|Chromosomes, Mammalian|Systole|Diastole|Insulin|Disease Models, Animal|ERCC6 protein, human|Poly-ADP-Ribose Binding Proteins 34 CILP2 26905813 Endocr. Res. 2016 10.3109/07435800.2016.1141945 2 0 0 28 *Metabolic Syndrome|Genome-Wide Association Study|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Gene Frequency|Obesity|Risk Factors|Tunisia 34 CILP2 26850992 Circ Cardiovasc Genet 2016 PMC4838530 10.1161/CIRCGENETICS.115.001246 3 9 0 28 *Insulin Resistance|*Triglycerides|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Blood Glucose|Genotype|Phenotype|Body Mass Index|Genetic Variation|Life Style 34 CILP2 26758378 Lipids Health Dis 2016 PMC4711176 10.1186/s12944-016-0181-z 1 4 1 28 Humans|*Non-alcoholic Fatty Liver Disease|*Ethnic Groups|*Neurocan|*Asian|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genetic Association Studies|Linkage Disequilibrium|Chondroitin Sulfate Proteoglycans|Liver|Genotype|Triglycerides|Nerve Tissue Proteins|Membrane Proteins|Lectins, C-Type|Case-Control Studies|NCAN protein, human|TM6SF2 protein, human 34 CIZ1 28036012 Biomolecules 2016 PMC5372713 10.3390/biom7010001 3 71 0 143 Animals|*Cell Cycle Proteins|*Cell Transformation, Neoplastic|S Phase|Nuclear Proteins|DNA Replication|Cell Cycle|Cell Nucleus|Cyclin-Dependent Kinase 2|*Tumorigenesis|Chromatin|*Cell Cycle Checkpoints|Nuclear Matrix|Phosphorylation|Cyclin-Dependent Kinases 70 CIZ1 27934662 Biol Open 2016 PMC5278428 10.1242/bio.021550 1 6 0 143 Mice|Animals|*Myocytes, Cardiac|Nuclear Matrix|Nuclear Proteins|Cell Proliferation|Cell Cycle|Ciz1 protein, mouse 70 CIZ1 27867087 Clin. Biochem. 2016 PMC5441127 10.1016/j.clinbiochem.2016.11.015 2 2 0 143 Humans|Retrospective Studies|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Biomarkers, Tumor|Chromatography, Liquid|Tandem Mass Spectrometry|*Plasma|AUC|Enzyme-Linked Immunosorbent Assay 70 CIZ1 27163549 Exp. Neurol. 2016 PMC4992595 10.1016/j.expneurol.2016.05.006 8 7 0 143 Animals|Mice|*Mice, Inbred C57BL|*Phenotypes|*Genes, cdc|Cell Cycle|Nuclear Proteins|Dystonic Disorders|*Germ Line|*Cell Cycle Proteins|Brain|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Disease Models, Animal|DNA Replication|Cell Proliferation|Dystonia|Signal Transduction|Motor Activity|Gait 70 CKAP2 27055594 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.03.145 1 0 0 245 Mice|Animals|*Diploidy|Chromosome Segregation|*Cytoskeletal Proteins|Spindle Apparatus|Centrosome|Microtubules|Mitosis|Stability, Chromosomal|Chromosomes|2,5-dichloro-4-bromophenol|*Chlorophenols|*Hepatocyte 50 CKAP2 26956253 Eur. J. Hum. Genet. 2016 PMC4989203 10.1038/ejhg.2016.14 1 0 0 245 Humans|*Rubinstein-Taybi Syndrome|Filippi syndrome|*Facies|*Microcephaly|*Intellectual Disability|*Syndactyly|*Growth Disorders|*Mutation|CREB-Binding Protein|Sequencing, Whole Exome|Genetic Association Studies|Phenotype|CREBBP protein, human 50 CLEC11A 27976999 Elife 2016 PMC5158134 10.7554/eLife.18782 13 19 0 80 Humans|Adult|*Osteogenesis|Bone Marrow Stromal Cells|Cell Differentiation|Osteoblasts|Bone Marrow Cells|*Intercellular Signaling Peptides and Proteins|Osteocytes|Cell Proliferation|Cells, Cultured|*Skeleton|CLEC11A protein, human|Hematopoietic Cell Growth Factors|Lectins, C-Type 32 CLEC11A 27731420 Sci Rep 2016 PMC5059742 10.1038/srep35218 26 30 1 80 Animals|*Chromosome Instability|cohesins|Cell Cycle Proteins|Senescence, Replicative|Chromosomal Proteins, Non-Histone|Signal Transduction|Spindle Assembly Checkpoint|Cell Proliferation|Apoptosis|DNA Damage|Aging|Aneuploid Cells|*Chromosome Structures|Inflammation|Genes, cdc|Phenotype 32 CLEC11A 26973208 Lung Cancer 2016 10.1016/j.lungcan.2016.01.020 5 1 0 80 Humans|Italy|*Asbestos|Mesothelioma, Malignant|*Mesothelioma|Pleural Neoplasms|*Lung Neoplasms|Occupational Exposure|Occupational Diseases|Incidence|*Chemokines 32 CLIC5 27582103 Am. J. Physiol. Renal Physiol. 2016 10.1152/ajprenal.00353.2016 6 8 0 111 Mice|Animals|Endothelial Cells|radixin|Cytoskeletal Proteins|ezrin|moesin|Microfilament Proteins|CLIC4 protein, human|*Channel, Chloride|Membrane Proteins|*Kidney Glomerulus|Podocytes|Cytoskeleton|Actin|Phosphorylation|Cell Membrane|Proteinuria|Endothelium 55 CLIC5 27540136 Haematologica 2016 PMC5479611 10.3324/haematol.2016.149740 8 3 0 111 Humans|Child|Proto-Oncogene Proteins c-ets|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Core Binding Factor Alpha 2 Subunit|Translocation, Genetic|Oncogene Proteins, Fusion|Repressor Proteins|DNA-Binding Proteins|BIRC7 protein, human|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|CLIC5 protein, human|Microfilament Proteins|Chromatin Immunoprecipitation|Adaptor Proteins, Signal Transducing|Inhibitor of Apoptosis Proteins|Channel, Chloride|ANGPTL2 protein, human|Angiopoietin-like Proteins 55 CLIC5 27476875 Anim. Genet. 2016 10.1111/age.12482 8 0 1 111 Female|Male|Animals|*Genome-Wide Association Study|*Catfish|*Polymorphism, Single Nucleotide|Genetic Linkage|Quantitative Trait Loci|Channel Catfish|*Stress, Heat|Phenotype 55 CLIC5 27259918 Methods Mol. Biol. 2016 10.1007/978-1-4939-3615-1_1 3 0 0 111 Animals|*Transfection|Biolistic|*Ear, Inner|*Gene Transfer Techniques|*Epithelium|Hair Cells, Auditory, Inner|Green Fluorescent Proteins|DNA|Myosin|Actin|Gold|siRNA|Neurons|cDNA 55 CLIC5 27104215 Data Brief 2016 PMC4826591 10.1016/j.dib.2016.03.061 9 0 1 111 *Myocytes, Cardiac|CLIC4 protein, human|*Channel, Chloride|*Endoplasmic Reticulum|*Antibodies|Amino Acid Sequence 55 CLIC5 26924049 Kidney Int. 2016 10.1016/j.kint.2016.01.001 3 13 0 111 Mice|Animals|*Podocytes|*Channel, Chloride|*Kidney Glomerulus|ezrin|Cytoskeletal Proteins|podocalyxin|Sialoglycoproteins|Microfilament Proteins|Membrane Proteins|*Kidney Diseases|Phosphorylation|Actin|cdc42 GTP-Binding Protein|Albuminuria|*Cytoplasm|rac1 GTP-Binding Protein|*Protective Agents|Desoxycorticosterone Acetate 55 CLIC5 26786290 Epigenetics 2016 PMC4846113 10.1080/15592294.2016.1138195 23 0 1 111 Humans|Child|*Neuroblastoma|DNA Methylation|CpG Islands|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Genes, Neoplasm|*Genetic Profile|Cell Line, Tumor 55 CLIC5 26777142 Mitochondrion 2016 10.1016/j.mito.2016.01.001 16 0 3 111 Mitochondria, Heart|CLIC4 protein, human|Chloride Channels|Potassium Channels|Myocytes, Cardiac|Myocardial Reperfusion Injury|Mitochondrial Membrane, Outer|Reactive Oxygen Species|Chlorides 55 CLMP 27871939 Mol. Cell. Neurosci. 2016 10.1016/j.mcn.2016.11.009 11 0 0 63 Male|Animals|Mice|*Cell Adhesion Molecules|*Immunoglobulin|*Cell Communication|Cell Adhesion|adenovirus receptor|Receptors, Virus|Coxsackie and Adenovirus Receptor-Like Membrane Protein|Neural Cell Adhesion Molecules|Tight Junctions|Plasma Membrane|Membrane Protein 584 CLSTN2 27771533 Neuroscience 2016 10.1016/j.neuroscience.2016.10.030 1 0 0 215 Pregnancy|Child|Male|Female|Humans|*DNA Copy Number Variations|*Autistic Disorder|Autism Spectrum Disorder|*Genotype|Single Nucleotide Polymorphisms|*Databases, Genetic|Genome, Human|Pedigree|Oligonucleotide Microarrays|Phenotype|Genetic Testing 32 CMPK2 27733572 J. Leukoc. Biol. 2016 10.1189/jlb.5A0616-258R 6 1 0 29 Humans|*Tumor Necrosis Factor Inhibitors|*Neutrophils|*Rheumatoid Arthritis|Anti-Rheumatic Drugs|Tumor Necrosis Factor-alpha|*Biomarkers|Sequencing, RNA|Signal Transduction 21 CNN3 27836619 Biochim Biophys Acta Proteins Proteom 2016 10.1016/j.bbapap.2016.11.002 5 0 0 296 Humans|Female|*Proteomics|Chromatography, Liquid|Tandem Mass Spectrometry|MALDI|Proteome|Ovarian Neoplasms 39 CNN3 26970176 Gene 2016 PMC5325697 10.1016/j.gene.2016.02.040 24 30 0 296 calponin|*Actin Binding Proteins|*Actin Cytoskeleton|*Calcium-Binding Proteins|*Muscle, Smooth|Actin|Cytoskeleton|*Isoforms|Muscle Contraction|Smooth Muscle Cells|Amino Acid Sequence|Phosphorylation 39 CNPY2 27696085 Purinergic Signal. 2016 PMC5334196 10.1007/s11302-016-9536-1 1 0 0 91 Mice|Animals|*Transcriptome|*Endotoxemias|*Myocardium|Receptor, Adenosine A2A|Mice, Knockout|Adenosine 27 CNPY2 26835537 Am. J. 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Lymphoma 2016 10.1080/10428194.2016.1180690 3 0 0 74 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Prognosis|ZAP70 protein, human|*ZAP-70 Protein-Tyrosine Kinase|Immunoglobulin Variable Region|Immunoglobulin Heavy Chains|*Mutations|Lipoprotein Lipase|Biomarkers, Tumor|Cohort Studies|Gene Expression 29 COBLL1 26833246 Nat Commun 2016 PMC4740398 10.1038/ncomms10495 82 8 1 74 Humans|*Adiposity|Genome-Wide Association Study|*Obesity|Waist-Hip Ratio|Body Mass Index|Body Fat Distribution|Quantitative Trait Loci|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|Adipose Tissue|Cardiovascular Diseases|PLA2G6 protein, human|Group VI Phospholipases A2 29 COBLL1 26757982 Eur. J. Hum. Genet. 2016 PMC4970686 10.1038/ejhg.2015.272 1 0 0 74 Humans|Female|United States|*African Americans|*Waist-Hip Ratio|Genome-Wide Association Study|*National Heart, Lung, and Blood Institute (U.S.)|*Exome|Diabetes Mellitus, Type 2|*European Continental Ancestry Group|Genetic Loci|*Whole Exome Sequencing|Genetic Predisposition to Disease|Alleles|Polymorphism, Single Nucleotide|Body Fat Distribution|Genetic Variation|Abdominal Fat|Risk Factor 29 COBLL1 26751214 PLoS Pathog. 2016 PMC4708995 10.1371/journal.ppat.1005383 15 32 3 74 *Herpesvirus 4, Human|*Chromatin|EBNA-3C, epstein-barr virus|Epstein-Barr Virus Nuclear Antigens|*B Cells|histone H3 trimethyl Lys4|Histones|Chromatin Immunoprecipitation|Epstein-Barr Virus Infections|lymphocryptovirus nuclear antigen 3C|Antigens, Viral|Viral Proteins|*Gene Expression|Immunoglobulin J Recombination Signal Sequence-Binding Protein|Modifications, Histone|Polycomb-Group Proteins|Binding Sites 29 cornulin 27569371 Exp. Eye Res. 2016 10.1016/j.exer.2016.08.009 7 0 0 53 Humans|*Meibomian Glands|*Cells, Epithelial|Dry Eye Disease|*Gonadal Steroid Hormones|*Cell Count|Cells, Cultured|Cell Differentiation|Cell Line|Cell Proliferation|Lipogenesis|Serum|Oestradiol|HRNR protein, human|Calcium-Binding Proteins|Intermediate Filament Proteins 27 cornulin 27172385 Transl Res 2016 10.1016/j.trsl.2016.04.004 1 0 0 53 Humans|*Thyroid Nodule|*Biopsy, Fine-Needle|*Diagnosis, Differential|*Proteomics|Thyroid Cancer|Thyroid Gland|Adenocarcinoma, Follicular|Thyroidectomy|Sensitivity and Specificity|Receiver Operating Characteristic|Western Blot|Biomarkers|Annexin A1 27 COX6A2 27775717 Nature 2016 10.1038/nature20157 42 1 0 26 Animals|Mice|*Mitochondrial Membranes|Electron Transport Complex I|Electron Transport Complex IV|Chain, Respiratory|Mitochondria|Protein Isoforms 24 CPA4 27904708 Am J Transl Res 2016 PMC5126350 11 2 0 103 Humans|*Stomach Neoplasms|Tumor Markers|Prognosis|Immunohistochemistry|Lymphatic Metastasis|Kaplan-Meier Analysis|Adenocarcinoma|Disease Progression|Carboxypeptidases 37 CPA4 27780921 Oncotarget 2016 PMC5346670 10.18632/oncotarget.12798 6 1 0 103 Humans|*Colorectal Carcinoma|*Liver Neoplasms|Prognosis|Lymphatic Metastasis|Biomarkers, Tumor|Kaplan-Meier Estimate|Neoplasm Staging|Up-Regulation|Logistic Models 37 CPA4 27390594 J Cancer 2016 PMC4934027 10.7150/jca.15209 11 2 1 103 Humans|*Carcinoma, Non-Small-Cell Lung|antigen CYFRA21.1|*Lung Cancer|*Prognosis|Vascular Endothelial Growth Factor A|China|Keratin-19|Antigens, Neoplasm|Tumor Markers|Receiver Operating Characteristic|Lung|Lymphatic Metastasis 37 CPA6 27504264 Epilepsy Behav Case Rep 2016 PMC4969243 10.1016/j.ebcr.2016.04.003 3 1 1 44 Child|Male|Humans|Child, Preschool|Adolescent|*Semantics|*Autistic Disorder|Epilepsy, Rolandic|Landau-Kleffner Syndrome|Electroencephalography|Brain|*Autism Spectrum Disorder|Aphasia|Sleep|*Child Development Disorders, Pervasive|SCNM1 protein, human|RNA Splicing Factors 24 CPA6 27050163 PLoS ONE 2016 PMC4822968 10.1371/journal.pone.0152905 0 9 1 44 Humans|Animals|*Zebrafish|*Larvae|*mRNA|carboxypeptidase A6, human|Carboxypeptidases A|Pentylenetetrazole|Seizures|Febrile Seizures|Juvenile Myoclonic Epilepsy|Genes, fos|Epilepsy, Temporal Lobe|Mutations 24 CPVL 27643988 Neonatology 2016 10.1159/000448615 0 0 0 67 Infant|Humans|Infant, Newborn|*Leukomalacia, Periventricular|*Preterm Infants|*Risk Factors|*Prevalence|*Cerebral Hemorrhage|Gestational Age|Birth Weight|Retrospective Studies|Logistic Models 65 CPVL 27531224 Arch. Dis. Child. Fetal Neonatal Ed. 2016 10.1136/archdischild-2015-310313 6 0 0 67 Infant, Newborn|Infant|Pregnancy|Humans|Female|*Gestational Age|Infant, Extremely Premature|Intensive Care Units, Neonatal|Infant, Premature, Diseases|Infant Mortality|*Parturition|Morbidity 65 CPVL 27059074 Arch. Dis. Child. Fetal Neonatal Ed. 2016 10.1136/archdischild-2015-308579 9 0 0 67 Infant|Humans|Infant, Newborn|*Preterm Infants|Switzerland|Infant, Premature, Diseases|Gestational Age|*Morbidity|Infant, Very Low Birth Weight|Intensive Care, Neonatal|Infant Mortality|Intensive Care Units, Neonatal|Risk Factors 65 CPVL 27027607 Dev Med Child Neurol 2016 10.1111/dmcn.13047 5 0 0 67 Infant, Newborn|Infant|Humans|Cystic Periventricular Leukomalacia|*Brain|Cerebral Palsy|Infant, Premature|Intellectual Disability|Risk Factors|Stroke|Cognition 65 CPVL 26781425 Mol. Neurobiol. 2016 10.1007/s12035-016-9713-9 1 1 0 67 Infant|Humans|Infant, Newborn|*Cerebral Palsy|*Cyclooxygenase 2|*Infant, Premature|Cystic Periventricular Leukomalacia|*Infant, Very Low Birth Weight|PTGS1 protein, human|*Cyclooxygenase 1|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Infant, Premature, Diseases|Genotype|Interleukin-6|Brain 65 CPVL 26726899 Dan Med J 2016 0 0 0 67 Infant, Newborn|Infant|Female|Humans|Pregnancy|Child|*Infant, Extremely Premature|*Perinatal Care|Gestational Ages|Infant Mortality|Infant, Premature, Diseases|Infant, Very Low Birth Weight|Intensive Care, Neonatal|Intensive Care Units, Neonatal|Morbidity|Premature Birth|Survival Rate|Hospital Mortality|Risk Factors|Denmark 65 CRELD1 27029737 Genetics 2016 PMC4896192 10.1534/genetics.116.188045 9 1 0 38 Mice|Humans|Animals|*Down Syndrome|*Penetrance|Trisomy|*Heart Defects, Congenital|*Disease Models, Animal|Heart Septal Defects|CRELD1 protein, mouse|Cell Adhesion Molecules|Extracellular Matrix Proteins 32 CRIP1 27836662 Gene 2016 10.1016/j.gene.2016.11.009 2 0 0 104 Humans|Swine|Cattle|Mice|Animals|*Enterococcus faecalis|Sequence Alignment|Amino Acid Sequence|Base Sequence|Gene Expression Regulation|Cloning, Molecular|cDNA|Promoter Regions, Genetic|Gene Expression Profiling|Sequence Homology, Amino Acid|Phylogeny|*Cells, Epithelial|Cell Line|CRIP1 protein, human|Carrier Proteins|LIM Domain Proteins|Crip1 protein, mouse 80 CRIP1 27789726 J. Infect. Dis. 2016 PMC5225255 10.1093/infdis/jiw506 30 1 0 104 Humans|Female|*Monocytes|Antigens, Differentiation, Myelomonocytic|Anti-HIV Agents|Antigens, CD|Lipopolysaccharide Receptors|Receptors, Cell Surface|HIV Infections|Viral Load|Coinfection|Biomarkers|Plasma|Interleukin-6|Cognition|Cohort Studies 80 CROCC 28017616 Dev. Cell 2016 10.1016/j.devcel.2016.11.019 8 1 0 82 Humans|*Centrioles|*Centrosome|CNTRL protein, human|*Cell Cycle Proteins|Microtubules|Spindle Apparatus|Interphase|Cytoskeletal Proteins|Actin|Chromosome Segregation|Microfilament Proteins|Binding Proteins|HeLa Cells|GAS2L1 protein, human 32 CROCC 27872140 J. Clin. Pathol. 2016 10.1136/jclinpath-2016-204103 8 0 0 82 Humans|*Cilia|*Cancer|Signal Transduction 32 CROCC 27623382 Dev. Cell 2016 PMC5023068 10.1016/j.devcel.2016.07.013 0 15 0 82 Animals|Humans|*Basal Body|*Patient Positioning|Caenorhabditis elegans|Cilia|Centrioles|Caenorhabditis elegans Proteins|Sensory Neurons|Microtubules|Signal Transduction|Protein Transport 32 CROCC 27514831 BMC Genet. 2016 PMC4981989 10.1186/s12863-016-0423-0 0 1 1 82 Humans|*Genome-Wide Association Study|*DNA Copy Number Variations|*Forced Vital Capacity|Single Nucleotide Polymorphisms|Genotype|Phenotype|Algorithms|Cohort Studies|*Tidal Volume|BANP protein, human|DNA-Binding Proteins|Nuclear Proteins|Cell Cycle Proteins 32 CRTAC1 28000762 Sci Rep 2016 PMC5175167 10.1038/srep39586 0 11 0 35 Mice|Animals|*Olfactory Bulb|Nogo Proteins|Nogo Receptor 1|Axons|Growth Cones|*Signal Transduction|Neurons|Mice, Knockout|Calcium-Binding Proteins|*Neurogenesis|Cells, Cultured|*Limbic System|*White Matter 27 CRTAC1 27862299 Proteins 2016 10.1002/prot.25210 0 0 0 35 Animals|Humans|*Amyloidogenic Proteins|*Amyloid|*Amyloidosis|Amino Acid Sequence|Sequence Alignment|Protein Isoforms|Evolution, Molecular|Phylogeny|Sequence Homology, Amino Acid|Calcium-Binding Proteins|Extracellular Matrix Proteins|Cartilage|CRTAC1 protein, human 27 CRTAC1 27855397 Cell. 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Biochem. 2016 10.1159/000447920 3 6 0 35 Humans|*Apoptosis|*Ultraviolet Rays|Lens, Crystalline|Reactive Oxygen Species|Epithelial Cells|JNK Mitogen-Activated Protein Kinases|Membrane Potential, Mitochondrial|Cataract|p38 Mitogen-Activated Protein Kinases|Oxidative Stress|MAP Kinase Signaling System|*Mitogen-Activated Protein Kinase 9|*Mitogen-Activated Protein Kinase 14|Cell Line|Cartilage|CRTAC1 protein, human|Calcium-Binding Proteins 27 CRTAC1 27415616 PLoS ONE 2016 PMC4945026 10.1371/journal.pone.0159157 0 10 1 35 Humans|Male|Female|Mice|Animals|Proteomics|Chondrocytes|Cartilage, Articular|Arthritis, Experimental|Meniscus, Medial|Osteophyte|IL1B protein, human|Interleukin-1beta|Osteoarthritis, Knee|Mice, Knockout|Fluid, Synovial|Disease Models, Animal|Upregulation|Tumor Necrosis Factor-alpha|Disease Progression|CRTAC1 protein, human|Calcium-Binding Proteins|Crtac1 protein, mouse 27 CRTAC1 26824659 Cell 2016 PMC4733250 10.1016/j.cell.2015.12.049 11 14 0 35 Animals|*Mesenchyme|*Limb|*Sensory Receptor Cells|Gene Expression Regulation, Developmental|Muscle, Skeletal|Signal Transduction 27 CRYBB3 27326458 PLoS ONE 2016 PMC4915718 10.1371/journal.pone.0157005 6 0 1 14 beta-Crystallin B Chain|*Cataract|*Mutation|Genes, Recessive|Pedigree|DNA Mutational Analysis|Lod Score|Genetic Linkage|Haplotypes|Amino Acid Sequence|Microsatellite Repeats 36 CRYBB3 27307692 Mol. Vis. 2016 PMC4896834 16 0 0 14 Humans|*Cataract|*Asian Continental Ancestry Group|*Mutation|Crystallins|DNA Mutational Analysis|Pedigree|Connexins|High-Throughput Nucleotide Sequencing|Phenotype|Genotype 36 CRYBB3 27256633 Am. J. Med. Genet. A 2016 10.1002/ajmg.a.37685 0 0 0 14 Humans|Child|Male|Child, Preschool|DNA Copy Number Variations|Warburg Sjo Fledelius syndrome|Optic Atrophy|Microcephaly|Martsolf syndrome|Intellectual Disability|Hypogonadism|rab3 GTP-Binding Proteins|Abnormalities, Multiple|*Cataract|Homozygote|Cornea|Mutation|Pedigree|CRYBB3 protein, human|beta-Crystallin B Chain 36 CRYGC 27187112 Biochemistry 2016 PMC5391980 10.1021/acs.biochem.6b00359 1 0 0 132 Humans|*Solubility|gamma-Crystallins|Lens, Eye|Cataract|Amino Acid Sequence|*Magnetic Resonance Imaging|Models, Molecular|Mutations|*Nuclear Magnetic Resonance 65 CRYGC 26732753 Sci Rep 2016 PMC4702117 10.1038/srep18912 7 1 1 132 Humans|Cataract, zonular|*Cataract|gamma-Crystallins|*Chinese|DNA Mutational Analysis|Pedigree|Lens, Crystalline|Haplotype|Mutation|Heterozygote|Base Sequence|Allele|CRYGD protein, human 65 CRYGC 28530003 Open Access J Ophthalmol 2016 PMC5438206 0 0 0 132 Humans|*Alleles|Cataract, Autosomal Dominant|Cataract|Pedigree|Connexins|Amino Acid Substitution|Eye Proteins|Mutation, Missense|Base Sequence|Asian Continental Ancestry Group 65 CRYZ 26831219 Ann. Hum. Genet. 2016 10.1111/ahg.12146 7 0 0 488 Humans|Adult|DNA Methylation|Epigenesis, Genetic|Epigenetic|CpG Islands|Identical Twins|*Birth Weight|*Genomics|Genome, Human 164 CSMD2 27890662 Brain Behav. Immun. 2016 10.1016/j.bbi.2016.11.026 5 0 0 9 20 CSMD3 27939411 Gynecol. Oncol. 2016 10.1016/j.ygyno.2016.11.045 12 0 0 6 Humans|Female|Japan|*Adenocarcinoma, Clear Cell|*Sequencing, Next-Generation|Paraffin Embedding|Tissue Fixation|Ovarian Cancer|Exome|DNA, Neoplasm|Class I Phosphatidylinositol 3-Kinases|Formaldehyde|Nuclear Proteins|Mutation|Transcription Factors|*Ovary 41 CSMD3 27918551 Oncogenesis 2016 PMC5177775 10.1038/oncsis.2016.77 5 6 0 6 41 CSMD3 27367781 Am. J. Respir. Crit. Care Med. 2016 PMC5215031 10.1164/rccm.201602-0250OC 7 0 0 6 Humans|Child|*Asthma|Forced Expiratory Volume|Vital Capacity|Chronic Obstructive Pulmonary Disease|Lung|Polymorphism, Single Nucleotide|*Genomics|Phenotype 41 CST7 27807066 Cancer Genomics Proteomics 2016 PMC5219917 10.21873/cgp.20006 2 2 0 128 Mice|Animals|CCN Intercellular Signaling Proteins|Gene Expression Regulation, Neoplastic|phospholipase D2|Phospholipase D|Proto-Oncogene Proteins|Cell Line, Tumor|Signal Transduction|Cell Proliferation|Lymphoma|Transfections 39 CST8 27445316 Mol. Hum. Reprod. 2016 PMC5099997 10.1093/molehr/gaw049 9 2 0 190 Male|Mice|Animals|*Cystatin B|*Epididymis|Sperm Maturation|*Spermatogenesis|*Cystatins|*Amyloid|*Amyloidogenic Proteins|*Amyloidosis|Spermatozoa|*Extracellular Vesicles|*Transcription Factors 31 CTAGE1 27861978 Allergy 2016 10.1111/all.13080 2 0 0 3 Dermatitis, Atopic|T-Lymphocyte Subsets|Antigens, Differentiation, T-Lymphocyte|Receptors, Lymphocyte Homing|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Lymphocyte Activation|CD3 Complex|Immunophenotyping|Skin|Antigens, Neoplasm|Membrane Glycoproteins 238 CTAGE1 27764137 PLoS ONE 2016 PMC5072666 10.1371/journal.pone.0164543 2 7 1 3 Humans|*T Cell Receptor|CD8-Positive T-Lymphocytes|Mycobacterium leprae|T-box transcription factor TBX21|*T-Box Domain Proteins|T-Cell Subsets|CD4-Positive T-Lymphocytes|Receptors, Lymphocyte Homing|Antigens, Differentiation, T-Lymphocyte|*Leprosy, Borderline|Skin|*Gene Expression|Membrane Glycoproteins|Antigens, Neoplasm|Lepromatous, Borderline 238 CTAGE1 27180111 J. Invest. Dermatol. 2016 10.1016/j.jid.2016.04.030 5 3 0 3 Mice|Animals|*Epidermis|IL17A protein, human|IL-17A|*Epidermal Cells|ribonuclease B|*RNase|Keratinocytes|Psoriasis|Skin|*Monocyte Chemoattractant Proteins|Imiquimod|STAT3 protein, human|STAT3 Transcription Factor|Signal Transduction|Gene Expression Regulation|Cell Differentiation|Inflammation 238 CTAGE1 27128095 PLoS ONE 2016 PMC4851416 10.1371/journal.pone.0154594 3 1 0 3 Humans|*Plasma Cells|Receptors, Lymphocyte Homing|Antibody-Producing Cells|L-Selectin|Integrins|Immune Response, Mucosal|Antibodies, Bacterial|B-Lymphocyte Subsets|*Tonsillitis|*Sinusitis 238 CTAGE1 27056267 J. Allergy Clin. Immunol. 2016 10.1016/j.jaci.2016.02.008 9 0 0 3 Humans|*Streptococcus pyogenes|6-sulfo sialyl Lewis X|*Th17 Cells|*Psoriasis|Oligosaccharides|*Skin|*Epidermis|Lewis X Antigen|Interleukin-17|Keratinocytes|Antigens, Differentiation, T-Lymphocyte|Pharyngitis|HLA-C*06 antigen|HLA-C Antigens 238 CTAGE1 27003337 Genet Test Mol Biomarkers 2016 10.1089/gtmb.2015.0210 0 0 0 3 Humans|Genome-Wide Association Study|*Tuberculosis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Gene Frequency|Genotype|Case-Control Studies|Tuberculosis, Pulmonary 238 CTAGE1 26940855 Australas. J. Dermatol. 2016 10.1111/ajd.12456 5 0 1 3 Humans|*Mucosal-Associated Invariant T Cells|*Dermatitis Herpetiformis|Antigens, Differentiation, T-Lymphocyte|Lymphocyte Activation|Antigens, CD|Lectins, C-Type|Cytokines|Flow Cytometry|Tissues, Mucosal 238 CTAGE1 26918560 Med Sci Sports Exerc 2016 10.1249/MSS.0000000000000914 3 0 0 3 *Natural Killer Cells|CD8-Positive T-Lymphocytes|*Skin|Antigens, Differentiation, T-Lymphocyte|Immunologic Memory|Lymphocyte Activation|CD4-Positive T-Lymphocytes|Receptors, Lymphocyte Homing|P-selectin ligand protein|Membrane Glycoproteins|Leukocyte Common Antigens|Antigens, Neoplasm 238 CUZD1 27717419 Adv Clin Chem 2016 10.1016/bs.acc.2016.06.002 9 0 0 24 Humans|*Crohn Disease|*Autoimmunity|Genome-Wide Association Study|Colitis, Ulcerative|Autoantibodies|GPI-Linked Proteins|Autoantigens|Fluorescent Antibody Technique, Indirect|*Phenotype|Inflammatory Bowel Diseases|Immunoglobulin G|Intestines|Enzyme-Linked Immunosorbent Assay|Biomarkers|Inflammation|Pancreas|Membrane Proteins|Innate Immune Responses 35 CUZD1 27685470 PLoS ONE 2016 PMC5042506 10.1371/journal.pone.0163932 8 3 1 24 Animals|Female|*Chickens|*Gastrointestinal Microbiome|*Cecum|Microbiota|*Intestinal Mucosa|RNA, Ribosomal, 16S|Gene Expression 35 CUZD1 27458598 Neurol Neuroimmunol Neuroinflamm 2016 PMC4946772 10.1212/NXI.0000000000000255 2 1 1 24 Humans|*Autoantibodies|Receptors, Glutamate|*Hematopoietic Stem Cell Transplantation|*Stem Cell Transplantation 35 CUZD1 26778782 Behav. Brain Res. 2016 PMC4769651 10.1016/j.bbr.2016.01.018 7 1 0 24 Animals|Rats|*Cortex, Prefrontal|Conditioning, Classical|Fear|Amygdala|Freezing Reaction, Cataleptic|Immediate-Early Gene|Hippocampus|Rats, Long-Evans|Learning|Early Growth Response Protein 1|*Phobic Disorders|Electroshock 35 CYP4X1 27738743 Arch. Toxicol. 2016 PMC5399058 10.1007/s00204-016-1868-7 3 1 0 8 Humans|Reproducibility of Results|*Cells, Epithelial|Bronchi|*Cell Differentiation|Cells, Cultured|Gene Expression|Epithelial Tissue|CYP4Z1 protein, human|Cytochrome P450 Family 4 26 CYTL1 27835665 PLoS ONE 2016 PMC5105950 10.1371/journal.pone.0166480 4 12 0 57 Mice|Animals|*Signal Transduction|Receptors, Transforming Growth Factor beta|Fibrosis|Transforming Growth Factor beta|4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide|Dioxoles|Fibroblasts|Myofibroblasts|Receptor, Transforming Growth Factor-beta Type I|Protein-Serine-Threonine Kinases|Cell Transdifferentiation|Myocardium|Benzamides|CCL2 protein, human|Monocyte Chemoattractant Protein-1|Upregulation|Mice, Knockout|Disease Models, Animal 34 CYTL1 27590887 Cell Tissue Res. 2016 10.1007/s00441-016-2484-9 1 0 0 57 Animals|Chick Embryo|In Situ Hybridization|*Morphogenesis|Adenohypophysis|Pituitary Gland|mRNA|Ectoderm|Glycoprotein Hormones, alpha Subunit|Chickens|*Poly(ADP-ribose) Polymerases|*Genetic Marker|Connexins|Cytokines 34 CYTL1 27084102 J. Immunol. 2016 10.4049/jimmunol.1501908 10 0 1 57 Mice|Humans|Animals|*Monocytes|*Chemotaxis|HEK293 Cells|Receptors, CCR2|Chemokine CCL2|Macrophages|Cytokines|Signal Transduction|*Leukocytes|Lymphocytes|CYTL1 protein, human|Blood Proteins|CCR2 protein, human|Ccr2 protein, mouse 34 CYTL1 26800213 PLoS ONE 2016 PMC4723121 10.1371/journal.pone.0147424 5 9 1 57 Female|Mice|Animals|*Implantation, Embryo|LIF protein, human|Inhibitory Factor, Leukemia|Endometrium|Cell Adhesion|Cell Line|Chondrogenesis 34 DACT2 27708215 Oncotarget 2016 PMC5340116 10.18632/oncotarget.12341 0 46 0 129 Glycogen Synthase Kinase 3|*Promoter Regions, Genetic|*Epithelial-Mesenchymal Transition|CpG Islands|DNA Methylation|Cell Proliferation|Wnt Signaling Pathway|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Gene Silencing|Decitabine|Cell Line, Tumor|Apoptosis|Downregulation|Cell Movement|*Cytoskeleton|Carrier Proteins|Genes, Tumor Suppressor 53 DACT2 27553089 Clin Oral Investig 2016 PMC5442212 10.1007/s00784-016-1946-5 0 31 0 129 Humans|*Squamous Cell Carcinoma of Head and Neck|*Wnt Signaling Pathway|*Hedgehog Proteins|*Prognosis|DNA Methylation|Head and Neck Cancer|Epigenesis, Genetic|Neoplasm Proteins|Promoter Regions, Genetic|Carcinoma, Squamous Cell|Cell Line, Tumor|Carrier Proteins|Gene Expression Regulation, Neoplastic|Adaptor Proteins, Signal Transducing|CXXC4 protein, human|DNA-Binding Proteins|Transcription Factors|DACT2 protein, human 53 DAOA 27815320 J. Biochem. 2016 10.1093/jb/mvw064 2 0 0 34 Animals|*Schizophrenia|DAO protein, human|D-Amino-Acid Oxidase|Genetic Predisposition to Disease|Bipolar Disorder|Polymorphism, Single Nucleotide|Haplotypes|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Sequences, Amino Acid|*Models, Structural|Primates 168 DAZ1 27774720 Reprod. Domest. Anim. 2016 10.1111/rda.12848 0 0 0 63 Humans|Male|Dogs|Animals|*Spermatogenesis|Spermatogonia|Testis|Seminiferous Tubules|Adult Germline Stem Cells|Glial Derived Neurotrophic Factor Receptor 1|Spermatocytes|Azoospermia|*Proteins|Stem Cells|POU5F1 protein, human|Octamer Transcription Factor-3|Proto-Oncogene Proteins c-kit|Flow Cytometry|Cell Differentiation|Cells, Cultured 205 DAZ1 27739146 Andrologia 2016 10.1111/and.12527 0 0 0 63 Humans|Male|*Azoospermia|*Oligospermia|*DNA Copy Number Variations|Iran|Deleted in Azoospermia 1 Protein|Infertility, Male|Chromosomes, Human, Y|Spermatogenesis|Chromosome Deletion|Limulus clotting factor C|*Arthropod Proteins|*Serine Endopeptidases|Genetic Loci|Gene Deletion|Case-Control Studies|Gene Dosage 205 DAZ1 27723784 PLoS ONE 2016 PMC5056753 10.1371/journal.pone.0163936 2 0 1 63 Humans|Male|*Azoospermia|*Gene Conversion|Deleted in Azoospermia 1 Protein|Oligospermia|Infertility, Male|Chromosomes, Human, Y|Spermatogenesis|Gene Deletion|RNA-Binding Proteins|Case-Control Studies|Gene Dosage|Nuclear Proteins 205 DAZ1 26931020 Zhonghua Nan Ke Xue 2016 0 0 0 63 Humans|Male|*Azoospermia|Deleted in Azoospermia 1 Protein|*Infertility, Male|Oligospermia|Chromosomes, Human, Y|Spermatogenesis|Haplotypes|Gene Deletion|Asian Continental Ancestry Group|RNA-Binding Proteins|Case-Control Studies 205 DAZ3 27723784 PLoS ONE 2016 PMC5056753 10.1371/journal.pone.0163936 2 0 1 1 Humans|Male|*Azoospermia|*Gene Conversion|Deleted in Azoospermia 1 Protein|Oligospermia|Infertility, Male|Chromosomes, Human, Y|Spermatogenesis|Gene Deletion|RNA-Binding Proteins|Case-Control Studies|Gene Dosage|Nuclear Proteins 20 DAZ3 26931020 Zhonghua Nan Ke Xue 2016 0 0 0 1 Humans|Male|*Azoospermia|Deleted in Azoospermia 1 Protein|*Infertility, Male|Oligospermia|Chromosomes, Human, Y|Spermatogenesis|Haplotypes|Gene Deletion|Asian Continental Ancestry Group|RNA-Binding Proteins|Case-Control Studies 20 DBR1 27930312 Proc. 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U.S.A. 2016 PMC5187747 10.1073/pnas.1612729114 9 0 0 69 lariat debranching enzyme|*RNA|*RNA Nucleotidyltransferases|RNA Splicing|Introns|Entamoeba histolytica|*Metals|RNAs, Circular 63 DBR1 27870853 PLoS Genet. 2016 PMC5147768 10.1371/journal.pgen.1006422 13 9 0 69 *Arabidopsis|*Introns|Arabidopsis Proteins|Ribonuclease III|RNA-Binding Proteins|miRNA, Primary|Cell Cycle Proteins|Serrate-Jagged Proteins|Calcium-Binding Proteins|Membrane Proteins|Mutation|Allele|HYL1 protein, Arabidopsis|DBR1 protein, Arabidopsis|RNA Nucleotidyltransferases 63 DBR1 27765821 RNA 2016 PMC5113202 10.1261/rna.058552.116 3 0 0 69 *Saccharomyces cerevisiae|*RNA|*Manganese|nitrophenylphosphate|*Nitrophenols|*Yeast, Dried|RNA Nucleotidyltransferases|Introns|RNA Splicing|RNA Precursors|bis(4-nitrophenyl)phosphate|Amino Acid Sequence|Active Site|Structure-Activity Relationships|Phosphoric Diester Hydrolases 63 DBR1 26797105 Sci Rep 2016 PMC4726175 10.1038/srep19848 36 3 6 69 Carcinoma, Renal Cell|Kidney Neoplasms|Von Hippel-Lindau Tumor Suppressor Protein|von Hippel-Lindau Disease|*Phenotypes|Mutation|*Protein Stability|Transcription Factors|*Mutagenesis|Mutations, Missense|Genotype|Amino Acid Sequence 63 DBR1 26721232 Immunol. Lett. 2016 10.1016/j.imlet.2015.11.016 1 0 0 69 Female|Humans|*Fetal Blood|*Prevalence|HLA Typing|*Antilymphocyte Serum|Isoantibodies|HLA-DRB1 Chains|HLA-B|Alleles|Autoantibodies|*Mother|Genes, MHC Class I 63 dd3 27915259 J Public Health (Oxf) 2016 10.1093/pubmed/fdw138 3 0 0 474 Humans|*Pharmacies|*Dependences, Opioid|Replacement Therapy, Opiate|Community Pharmacy Services|*Heroin|Pharmacists|Professional Role|Attitude of Health Personnel 125 dd3 27743381 Tumour Biol. 2016 10.1007/s13277-016-5450-y 17 7 0 474 Humans|Male|*RNA, Long Noncoding|prostate cancer antigen 3, human|*Antigens, Neoplasm|PSCA protein, human|*Prostate Cancer|*Prostate|*Up-Regulation|*Neoplasm Proteins|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|*GPI-Linked Proteins|Cell Line, Tumor|*Transcriptional Activation|Tumorigenesis|Cell Movement|Disease Progression|*Neoplastic Processes 125 dd3 27518860 J Youth Adolesc 2016 10.1007/s10964-016-0555-6 2 0 0 474 Adolescent|Humans|Child|Young Adult|Adult|Randomized Controlled Trials as Topic|School|Health Promotion|Risk Behavior|Adolescent Behavior 125 DDX10 27902686 PLoS Genet. 2016 PMC5130177 10.1371/journal.pgen.1006449 9 39 0 68 Humans|*Metformin|Diabetes Mellitus, Type 2|*Liver|Gluconeogenesis|Hypoglycemic Agents|Hepatocytes|AMP-Activated Protein Kinase|Protein-Serine-Threonine Kinases|*Genomics|SNPs|DDX10 protein, human|DEAD-box RNA Helicases|EXPH5 protein, human|Adaptor Proteins, Signal Transducing 29 DDX60 27835882 Oncotarget 2016 PMC5356722 10.18632/oncotarget.13197 10 18 0 64 Humans|Male|*Carcinoma, Squamous Cell|*Oral Cancer|*Prognosis|Neoplasm Staging|Biomarkers, Tumor|Immunohistochemistry|Gene Expression Regulation, Neoplastic|Tumorigenesis|Cell Line, Tumor|Kaplan-Meier Estimate|Disease-Free Survival|DEAD-box RNA Helicases|DDX60 protein, human 35 DDX60 27630638 Front Immunol 2016 PMC5005343 10.3389/fimmu.2016.00335 30 21 1 64 Humans|Animals|*Hepatitis B virus|*Exosomes|*Hepatitis B Virus Infection|*Innate Immune Responses|*Extracellular Vesicles|Hepatocytes|RNA, Micro|Interferon|Host-Pathogen Interactions|NK Cells|Infection, Viral|Macrophages|Antiviral Agents|Interferon-gamma|Liver|Signal Transduction 35 DDX60 27542257 Oncotarget 2016 PMC5308654 10.18632/oncotarget.11348 2 2 0 64 Humans|*Hepacivirus|*Ribavirin|*Leukocytes, Mononuclear|Hepatitis C, Chronic|Antiviral Agents|Interferon-alpha|Interferon alpha-2|Viral Load|Polyethylene Glycols|Genotype|Drug Therapy, Combination|RNA, Viral|Treatment Efficacy|Sustained Virologic Response|*Gene Expression|Hepatitis C|IFITM3 protein, human|Membrane Proteins 35 DDX60 27271988 Mol Ther Nucleic Acids 2016 PMC5022127 10.1038/mtna.2016.34 12 5 1 64 Mice|Animals|*B-DNA|*Up-Regulation|*DNA|*B16 Melanoma|Electroporation|Transfection|Plasmids|*Cytosol|Gene Transfer Techniques|*Transcriptional Activation|Genetic Therapy|Receptors, Pattern Recognition|mRNA 35 DDX60 27252702 Front Immunol 2016 PMC4879126 10.3389/fimmu.2016.00200 18 26 1 64 *RNA, Viral|DDX58 protein, human|DEAD Box Protein 58|TRIM25 protein, human|Tripartite Motif Proteins|*Innate Immune Response|Ubiquitin-Protein Ligases|Interferon-Induced Helicase, IFIH1|DEAD-box RNA Helicases|*Cytoplasm|Transcription Factors|Type I Interferon|RNA, Double-Stranded|*Antiviral Agents|Signal Transduction|Phosphorylation|Ubiquitin|Infection, Viral 35 DDX60 26907498 Genome Biol Evol 2016 PMC4824011 10.1093/gbe/evw032 19 9 1 64 Animals|*Chickens|*Altitude|Tibet|*Ultraviolet Rays|*Acclimatization|*Genome|*Adaptation, Physiological|*Hypoxia|Frequencies, Allele|Genetics, Population|*Environment|Single Nucleotide Polymorphisms|Oxygen 35 DEXI 27723758 Nat. Genet. 2016 PMC5086090 10.1038/ng.3675 11 7 0 27 Humans|Immunoglobulin a deficiency 1|*IgA Deficiency|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Autoimmune Diseases|Case-Control Studies|*Transcription Factors|AHI1 protein, human|Adaptor Proteins, Signal Transducing|CLEC16A protein, human|Monosaccharide Transport Proteins|Lectins, C-Type|ATG13 protein, human|Autophagy-Related Proteins|AMBRA1 protein, human 30 DEXI 29462528 Afr J Med Med Sci 2016 0 1 0 27 Pregnancy|Female|Humans|Rats|Animals|*Rats, Wistar|*Oxidative Stress|*Lactation|Malondialdehyde|Catalase|Kidney|Superoxide Dismutase|*Biomarkers|Lipid Peroxidation|Antioxidants|Creatinine|Maternal Exposure|*Urinary Tract Physiological Phenomena|Dexamethasone 30 DGCR2 27375131 Am. J. Med. Genet. A 2016 10.1002/ajmg.a.37831 1 0 0 182 Humans|Male|Child|Marden Walker like syndrome|Congenital contractural arachnodactyly|*Arachnodactyly|Marden-Walker syndrome|*Blepharophimosis|*Contracture|*Abnormalities, Multiple|Scavenger Receptors, Class F|Hand Deformities, Congenital|Connective Tissue Diseases|Ehlers-Danlos Syndrome, musculocontractural type 1|Ehlers-Danlos Syndrome|Facies|Homozygote|Musculoskeletal Abnormalities|Syndrome|Phenotype|SCARF2 protein, human 22 DGCR6 27605457 Sci Rep 2016 PMC5015085 10.1038/srep32818 5 5 1 67 Humans|*lncRNA|*Transcriptome|*Dermatomyositis|*Transcriptome Profiling|Oligonucleotide Array Sequence Analysis|Gene Ontology|mRNA|Gene Regulatory Networks|Bioinformatics|Up-Regulation|Signal Transduction|Genome|Downregulation 24 DGCR6 26978485 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2016 10.1002/ajmg.b.32416 1 0 0 67 Humans|*Proline Dehydrogenase|*Autism Spectrum Disorder|*Risk Factors|Case-Control Studies|Velo-Cardio-Facial Syndrome|Amino Acid Metabolism, Inborn Errors|Mutations, Missense|Chromosome Deletion|Alleles|Genetic Predisposition to Disease|Phenotype|Proline|DGCR6 protein, human|Extracellular Matrix Proteins|PRODH protein, human 24 DHRS2 27195521 Cancer Biol. Ther. 2016 PMC4990404 10.1080/15384047.2016.1190485 3 5 0 173 Humans|*Adenoviruses|*Adenoviridae Infections|*Carcinoma, Renal Cell|CD46 protein, human|Membrane Cofactor Protein|Oncolytic Virotherapy|Genetic Vectors|Renal Cancers|Genetic Therapy|Coxsackie and Adenovirus Receptor-Like Membrane Protein|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2|adenovirus receptor|Receptors, Virus|Cell Line, Tumor|Xenograft Model Antitumor Assays|*DNA Replication|Apoptosis 35 DHX33 27693040 Mol Oncol 2016 PMC5423132 10.1016/j.molonc.2016.09.001 0 5 0 151 Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|3' UTR|Cell Movement|Genes, Tumor Suppressor|Hep G2 Cells|Cell Line, Tumor|Apoptosis|Down-Regulation|Mice, Nude 25 DHX33 27601587 Mol. Cell. Biol. 2016 PMC5108879 10.1128/MCB.00314-16 0 8 0 151 Humans|Carcinoma, Non-Small-Cell Lung|Lung Cancer|Cell Proliferation|*Cell Cycle|CCND1 protein, human|Cyclin D1|DEAD-box RNA Helicases|Cell Line, Tumor|RNA Interference|Apoptosis|*Cell Division|Cell Cycle Checkpoints|RNA Polymerase II|Promoter Regions, Genetic|Tumorigenesis|Cell Transformation, Neoplastic|DHX33 protein, human 25 DHX33 27073163 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.04.033 3 0 0 151 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Neoplasm Recurrence, Local|Kaplan-Meier Analysis|Survival Analysis|Up-Regulation|Cohort Studies|DHX33 protein, human|DEAD-box RNA Helicases 25 DHX33 26987611 Cytokine Growth Factor Rev. 2016 10.1016/j.cytogfr.2016.02.008 3 0 0 151 Male|2-5A-dependent ribonuclease|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|*Endoribonucleases|DDX58 protein, human|DEAD Box Protein 58|Double-Stranded RNA|2',5'-oligoadenylate|Oligoribonucleotides|interferon type III|Interferons|Carrier Proteins|DEAD-box RNA Helicases|RNA, Viral|Immunity, Innate|Infection, Viral|Adenine Nucleotides 25 DKKL1 27826023 Gene 2016 10.1016/j.gene.2016.11.004 0 0 0 98 Humans|*Alleles|*HeLa Cells|*RNA Splicing|Exons|Alternative Splicing|Introns|RNA Splice Sites|RNA, Messenger|Protein Isoforms|Single Nucleotide Polymorphisms|Transcription Factor|Computational Biology|Mutations|DKKL1 protein, human|Intercellular Signaling Peptides and Proteins|ZNF419 protein, human|DNA-Binding Proteins 22 DKKL1 27635108 Dis. Markers 2016 PMC5007337 10.1155/2016/1987505 4 3 1 98 Humans|Male|*Prognosis|*Testis|*Colorectal Cancer|MAGEA3 protein, human|Neoplasm Proteins|Antigens, Neoplasm|KDM5B protein, human|Jumonji Domain-Containing Histone Demethylases|Gene Expression Regulation, Neoplastic|Repressor Proteins|Biomarkers, Tumor|Nuclear Proteins|Membrane Proteins|DNA Methylation|mRNA|Cell Line, Tumor|*Colon Cancer|Gene Expression Profiling 22 DLEC1 27646854 Epigenetics 2016 PMC5094635 10.1080/15592294.2016.1214781 22 21 1 54 Humans|Mice|Animals|*Carcinoma, Hepatocellular|guadecitabine|*DNA Methylation|*Liver Neoplasms|*Azacitidine|*Epigenetic|Genes, p16|DNA Modification Methylases|Liver|Histone H2a|Promoter Regions, Genetic|Fibrosis, Liver|Cell Line, Tumor|Oncogene|Genes, cdc|Glutathione S-Transferase pi|Cell Proliferation|Epigenesis, Genetic 69 DLEC1 27514913 Methods Mol. Biol. 2016 10.1007/978-1-4939-3789-9_2 0 0 0 54 Humans|*Centrosome|Cilia|Cell Cycle Proteins|Microtubules|GRB2 protein, human|*GRB2 Adaptor Protein|*Protein Domain|Western Blotting|Cell Line|Immunofluorescence Microscopy|DLEC1 protein, human|Tumor Suppressor Proteins 69 DLEC1 27287342 Med. Oncol. 2016 10.1007/s12032-016-0791-3 5 0 0 54 *Carcinoma, Non-Small-Cell Lung|*Lung Cancer|DNA Methylation|Tumor Suppressor Proteins|Promoter Regions, Genetic|Prognosis|Genes, Tumor Suppressor|Squamous Cell Carcinoma|integrin alpha 9, human|*Integrins|Biomarkers, Tumor|Downregulation|Lung 69 DLEC1 27168825 Exp Ther Med 2016 PMC4840737 10.3892/etm.2016.3092 0 1 0 54 Humans|DNA Methylation|Promoter Regions, Genetic|Leukemia, Myeloid, Acute|Cyclin Dependent Kinase Inhibitor 2B|Gene Expression Regulation, Leukemic|Tumor Suppressor Proteins|Cell Line, Tumor 69 DLEC1 26834787 Hepat Mon 2016 PMC4723729 10.5812/hepatmon.29829 1 27 1 54 *Genes, Tumor Suppressor|*Downregulation|Tumor Suppressor Proteins|Cell Proliferation|Cell Line, Tumor 69 DMRTA2 28031177 Cereb. Cortex 2016 PMC6059253 10.1093/cercor/bhw384 7 0 0 12 Mice|Animals|*Neocortex|*Neurogenesis|Transcription Factors|Hippocampus|Embryonic Development 25 DMRTA2 26757254 Clin. Genet. 2016 10.1111/cge.12734 6 0 1 12 Animals|Mice|*Nervous System Malformations|Lissencephaly|*Brain|Phenotype|Homozygote|Microcephaly|Pedigree|Whole Exome Sequencing|Mutation|Neurogenesis|Cerebral Cortex|Frameshift Mutation|Transcription Factor 25 DMXL2 28008729 Pediatr Obes 2016 10.1111/ijpo.12205 10 0 0 56 Child|Adult|Female|Humans|Body Mass Index|Obesity, Child|Weight Gain|*Phenotype|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Alleles|Mothers|Longitudinal Studies|Risk Factors 27 DMXL2 27957681 Mol. Neurobiol. 2016 PMC5684250 10.1007/s12035-016-0329-x 1 0 0 56 Animals|Humans|Female|Male|Infant, Newborn|KISS1 protein, human|*Kisspeptins|Sexual Maturation|*Hypothalamus|Neuropeptides|Gonadotropin-Releasing Hormone|*Primates|Neurons|Messenger RNA|*Genes, Tumor Suppressor|Reproduction|Signal Transduction|DMXL2 protein, human|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing 27 DMXL2 27657680 Genet. Med. 2016 10.1038/gim.2016.142 6 0 0 56 Nonsyndromic Deafness|*Deafness|Pedigree|Exome|Genes, Dominant|Genetic Linkage|Whole Exome Sequencing|Hearing Loss|Genetic Predisposition to Disease|Mutation, Missense|Mutation|Sequence Analysis, DNA 27 DMXL2 27142340 J. Proteome Res. 2016 10.1021/acs.jproteome.5b00883 8 0 0 56 Humans|*Splice Variants, Protein|Molecular Sequence Annotation|Alternative Splicing|Computational Biology|Algorithms|Machine, Support Vector|Machine Learning 27 DNAH9 27588449 Am. J. Hum. Genet. 2016 PMC5011060 10.1016/j.ajhg.2016.07.007 16 0 0 77 Humans|*Transcriptome|*Lung|Pulmonary Surfactant-Associated Protein C|Type-II Pneumocytes|Pulmonary Surfactant-Associated Protein B|Pulmonary Surfactant-Associated Protein A|Bronchi|Respiratory Epithelium|RNA, Messenger|Goblet Cells|SFTPA1 protein, human 40 DNAH9 27553781 BMC Dev. Biol. 2016 PMC4994401 10.1186/s12861-016-0128-7 6 5 1 77 Animals|*Cilia|*Sea Urchin|*Transforming Growth Factor beta|Gastrula|Nodal Protein|Body Patterning|Ectoderm|Embryo, Nonmammalian|Embryogenesis|Mesoderm|Signal Transduction|Gene Expression Regulation, Developmental|*Embryo, Mammalian 40 DNAH9 27353389 Genes Cells 2016 10.1111/gtc.12380 12 2 0 77 Humans|Mice|Animals|*Axoneme|*Cilia|DNAH9 protein, human|Axonemal Dyneins|Kartagener Syndrome|*Proteins|Exome|Mutation|Pedigree|Phenotype|Cytoplasm|Lrrc6 protein, mouse 40 DNAH9 27274004 J Biophotonics 2016 10.1002/jbio.201500308 1 0 0 77 Animals|Cricetinae|Cricetulus|Zinc Oxide|Metal Nanoparticles|Luminescence 40 DNAH9 27261005 G3 (Bethesda) 2016 PMC4978901 10.1534/g3.116.030791 7 0 1 77 Humans|Male|Mice|Animals|Adult|DNAH9 protein, human|Axonemal Dyneins|Axoneme|*Mutations|Cilia|*Hydrocephalus|leucine-rich repeat proteins|Proteins|Homozygote|Infertility, Male|Sequencing, Whole Exome|Phenotype|Pedigree|Missense Mutation|*Sinusitis 40 DNAH9 26909801 Am. J. Respir. Cell Mol. Biol. 2016 PMC4979367 10.1165/rcmb.2015-0353OC 33 0 0 77 Humans|Mice|Animals|*Cilia|*Axoneme|Axonemal Dyneins|Kartagener Syndrome|Exome|Pedigree|Mutations|Phenotype|Sequencing, Next-Generation|Transmission Electron Microscopy|Transmission Electron Microscopy Tomography|DNAH11 protein, human 40 dnajc10 27653456 Sci Rep 2016 PMC5032117 10.1038/srep33850 3 7 1 331 Humans|*Parkinson Disease|*Asian Continental Ancestry Group|Haplotypes|Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide 32 dnajc10 27546788 Mol. Cell 2016 PMC5010498 10.1016/j.molcel.2016.07.012 35 20 0 331 Chlorocebus aethiops|Animals|HSP40 Heat-Shock Proteins|molecular chaperone GRP78|Heat-Shock Proteins|glucose-regulated protein 170|*HSP70 Heat-Shock Proteins|Molecular Chaperones|Folding, Protein|Endoplasmic Reticulum|Glycoproteins|Protein Binding|Membrane Proteins|Adenosine Triphosphatases|COS Cells|*Quality Control 32 DNAJC14 27109633 Nat Commun 2016 PMC4848490 10.1038/ncomms11386 14 38 1 65 Proteomics|*Sulfate Transporters|Deafness, Autosomal Recessive 4|Vestibular Aqueduct|Hearing Loss, Sensorineural|Pendred syndrome|Goiter, Nodular|*Protein Transport|Membrane Transport Proteins|Mutation|*Molecular Chaperones|*HSP70 Heat-Shock Proteins|Cell Membrane|East Asia 20 DNAJC14 26739057 J. Virol. 2016 PMC4810624 10.1128/JVI.03077-15 10 3 0 65 *Yellow fever virus|Proteins, Viral Nonstructural|Virus Replication|Fever, Yellow|Molecular Chaperones|RNA, Viral|RNA Helicases|Serine Endopeptidases|Cell Line|*Folding, Protein|Protein Processing, Post-Translational 20 DNTT 27689405 Oncotarget 2016 PMC5342105 10.18632/oncotarget.12264 9 8 0 417 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Adenocarcinoma|*Lung|Lymphocyte Activation|CD8-Positive T-Lymphocytes|NK Cells|Squamous Cell Carcinoma|B Cells|Flow Cytometry|Leukocyte Common Antigens|Immunohistochemistry|Immune Tolerance 56 DOC2A 27091977 Proc. Natl. Acad. Sci. U.S.A. 2016 PMC4983831 10.1073/pnas.1522927113 10 3 0 31 *Protein Kinase C|*Phosphorylation|SYT1 protein, human|*Synaptotagmin I|Synaptic Transmission|Synaptic Vesicles|Presynaptic Terminals|Neurons|Synaptic Plasticity|Munc18 Proteins|1,2-diacylglycerol|Diglycerides|Hippocampus|Nerve Tissue Proteins 42 DOC2B 27605709 Mol. Biol. Cell 2016 PMC5170865 10.1091/mbc.E16-03-0184 7 39 0 90 *Syntaxin 1|*Calcium|SNAP25 protein, human|*Synaptosomal-Associated Protein 25|*Plasma Membrane|*Membrane Fusion|*Protein Binding|Calcium Channels|Exocytosis|Patch-Clamp Techniques|Nerve Tissue Proteins 55 DOC2B 27434670 Elife 2016 PMC4977156 10.7554/eLife.17262 18 12 1 90 *C2 Domains|SYT1 protein, human|Synaptotagmin I|Calcium-Binding Proteins|Synaptic Transmission|Exocytosis|Protein Domain|Nerve Tissue Proteins|Calcium|Cell Membrane|Protein Binding|Membrane Glycoproteins|Mutagenesis, Site-Directed 55 DPPA2 27353491 Int. J. Mol. Med. 2016 PMC4934932 10.3892/ijmm.2016.2658 3 3 1 42 Male|Mice|Animals|*Embryonic Stem Cells|Pluripotent Stem Cells|Mouse Embryonic Stem Cells|*Adult Germline Stem Cells|Transcription Factors|Spermatogonia|Cell Differentiation|Gene Expression Profiling|Gene Expression|Cell Proliferation|Epigenesis, Genetic 62 DPPA2 27336671 PLoS ONE 2016 PMC4918974 10.1371/journal.pone.0158046 4 6 1 42 Humans|Swine|Animals|*Induced Pluripotent Stem Cells|Cellular Reprogramming|*Transgene|Embryonic Stem Cells|Cell Differentiation|Transcription Factors|Germ Layers|Fibroblasts|Kruppel-Like Transcription Factors|Cells, Cultured|Genes, Homeobox|Promoter Regions, Genetic|*Epigenetic|Epigenesis, Genetic 62 DPPA2 26745102 Asian Pac. J. Cancer Prev. 2016 10.7314/apjcp.2015.16.18.8461 1 0 0 42 Humans|Male|*Stomach Neoplasms|Lymphatic Metastasis|Gastric Mucosa|Prognosis|Adenocarcinoma|Neoplasm Staging|Stomach|Biomarkers, Tumor|Neoplasm Invasiveness|TYRP1 protein, human|*Membrane Glycoproteins|Survival Rate|Disease Progression|Immunoenzyme Techniques|Real-Time Polymerase Chain Reaction|Follow-Up Studies|RNA, Messenger|DPPA2 protein, human 62 DRAM2 27764573 Autophagy 2016 PMC5324854 10.1080/15548627.2016.1241922 27 7 0 31 Humans|*Mycobacterium tuberculosis|*Monocytes|*Macrophages|*Autophagy|Tuberculosis|BECN1 protein, human|Beclin-1|MIRN144 microRNA, human|MicroRNAs|Autophagy-Related Protein 5|Autophagosomes|Gene Expression Regulation|3' Untranslated Region|Microbial Viability|Antimicrobial Cationic Peptides|*Anti-Infective Agents|Host-Pathogen Interactions|*Anti-Bacterial Agents 21 DRAM2 27740626 Cell Death Differ. 2016 PMC5299705 10.1038/cdd.2016.111 54 18 0 31 Humans|Animals|Mice|*RNA, Long Noncoding|*SCID Mouse|Leukemia, Promyelocytic, Acute|Tretinoin|*Autophagy|Cell Differentiation|*Oncogene Proteins|*Hematopoiesis|Oncogene Proteins, Fusion|Transcription Factors|RNA, Micro|Cell Line, Tumor|DRAM2 protein, human|Membrane Proteins 21 DRAM2 27518550 Eye (Lond) 2016 PMC5177757 10.1038/eye.2016.189 10 4 0 31 Humans|*Retinoblastoma|*RNA, Micro|*Apoptosis|Retinal Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Downregulation|Upregulation|Cell Line, Tumor|Retina|DRAM2 protein, human|Membrane Proteins 21 DRAM2 26720460 Invest. Ophthalmol. Vis. Sci. 2016 10.1167/iovs.15-17604 4 0 0 31 *Retinal Dystrophy|Visual Field Tests|Fluorescein Angiography|*Mutations|Electroretinography|Visual Acuity|Visual Fields|Tomography, Optical Coherence|Pedigree 21 EHBP1 28028537 Sci Adv 2016 PMC5161429 10.1126/sciadv.1601470 30 37 0 98 *Lipid Droplets|*Autophagy|Autophagosome|Lipid Metabolism|Hepatocytes|Lipids|Adaptor Proteins, Signal Transducing 29 EHBP1 27552051 Elife 2016 PMC5026484 10.7554/eLife.18675 16 28 1 98 Humans|*Gene Duplication|LIM Domain Proteins|Cytoskeletal Proteins|Endosomes|Adaptor Proteins, Signal Transducing|Protein Transport|rab GTP-Binding Proteins|Endocytosis|HeLa Cells 29 EHBP1 27272733 PLoS Genet. 2016 PMC4894640 10.1371/journal.pgen.1006093 11 39 1 98 Animals|Caenorhabditis elegans|*Actins|*Endosomes|Caenorhabditis elegans Proteins|rab GTP-Binding Proteins|Endocytosis|Vesicular Transport Proteins|Protein Transport|GTPase-Activating Proteins|*Actin Cytoskeleton|Intestinal Epithelium|Biological Transport|RAB-10 protein, C elegans|EHBP-1 protein, C elegans 29 EHBP1 26967244 Oncotarget 2016 PMC5008361 10.18632/oncotarget.7926 3 0 1 98 Humans|Male|*Genetic Association Studies|*Prostate Cancer|Alleles|Genetic Predisposition to Disease|Case-Control Studies|3-Oxo-5-alpha-Steroid 4-Dehydrogenase|Polymorphism, Single Nucleotide|HOXB13 protein, human|Homeodomain Proteins|Genotype|FOXP4 protein, human|Forkhead Transcription Factors|SRD5A2 protein, human|Membrane Proteins 29 EIF1AY 27284354 Exp Ther Med 2016 PMC4887809 10.3892/etm.2016.3252 4 0 0 31 Humans|*Computational Biology|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Profile, Gene Expression|Gene Expression Profiling|Databases, Genetic|Software|*Heart Failure|Gene Expression Regulation, Neoplastic|Microarray Analysis|Signal Transduction|Upregulation|*Myocardial Ischemia|Cardiomyopathies 26 EIF1AY 27103889 Genomics Inform 2016 PMC4838528 10.5808/GI.2016.14.1.34 2 0 1 31 Humans|Male|CpG Islands|Oligonucleotide Array Sequence Analysis|Genome, Human|DNA Methylation|RNA, Long Noncoding 26 EIF1AY 26858897 Cell Med 2016 PMC4733840 10.3727/215517914X685178 3 0 0 31 Female|Humans|*Induced Pluripotent Stem Cells|*Embryonic Stem Cells|*Cell Differentiation|Cellular Reprogramming|Pluripotent Stem Cells|*Insulin|Cell Line|Gene Expressions|*Complement Factor B|Fibroblasts|3'-(1-butylphosphoryl)adenosine|Genome, Human 26 ELK4 27498548 J Pathol Transl Med 2016 PMC5042897 10.4132/jptm.2016.05.20 5 8 1 234 *Carcinoma, Hepatocellular|*Liver Neoplasms|Histones|Sirtuins|Histone Deacetylases|Cell Line, Tumor 110 ELK4 26938874 PLoS ONE 2016 PMC4777538 10.1371/journal.pone.0150382 9 5 1 234 Humans|Male|*RNA|ets-Domain Protein Elk-4|prostein|*Membrane Proteins|Transcription, Genetic|Prostate Cancer|RNA Splicing|Base Sequence|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Membrane Transport Proteins|*Chimera|ELK4 protein, human|SLC45a3 protein, human 110 ENOSF1 27995989 Pharmacogenomics J. 2016 10.1038/tpj.2016.81 4 0 0 12 Humans|*Stomach Neoplasms|*Prospective Studies|*Platinum|*Pharmacogenomic Variants|Docetaxel|Capecitabine|*Pharmacogenetics|Oxaliplatin|Organoplatinum Compounds|Taxoids|*Pharmacogenomic Testing|Fluorouracil|*Stomach|ERCC2 protein, human|Xeroderma Pigmentosum Group D Protein|Antineoplastic Combined Chemotherapy Protocols|Cisplatin|glutathione S-transferase T1 23 ENOSF1 26954118 Asian-australas. J. Anim. Sci. 2016 PMC5003983 10.5713/ajas.15.0724 0 1 1 12 Female|Animals|Cattle|*Follicular Fluid|*Proteomics|Two Dimensional Gel Electrophoresis|Proteome|Ovarian Follicle|*Estrus|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Western Blotting|Software 23 EPB41L4B 26872740 BMC Genet. 2016 PMC4752738 10.1186/s12863-016-0351-z 6 0 1 90 Humans|*Whole Exome Sequencing|*Exome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pedigree|Sequence Analysis, DNA|Gastric Cancer|*Stomach|Colorectal Cancer|*Rectal Cancer 23 EPC2 27762073 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2016 10.1002/ajmg.b.32503 11 0 0 66 Humans|Adult|Epigenesis, Genetic|*Schizophrenia|Psychosis|Cognition Disorders|Schizophrenic Psychology|SNPs|Genome-Wide Association Study|Neuropsychological Tests|Genetic Predisposition to Disease|Working Memory|Cognition|Genotype|Alleles|Cognitive Dysfunction|*Gene Expression|Episodic Memory|KDM3B protein, human|Jumonji Domain-Containing Histone Demethylases 54 EPC2 27706612 Genet. Mol. Res. 2016 10.4238/gmr.15038026 1 0 0 66 Humans|*Esophageal Neoplasms|Esophageal Squamous Cell Carcinoma|*src Tyrosine Kinases|Carcinoma, Squamous Cell|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Esophagus|Lymphatic Metastasis|Biomarkers, Tumor|Gene Knockdown Techniques|Immunohistochemistry|RNA, Messenger 54 EPC2 26992000 PLoS ONE 2016 PMC4798725 10.1371/journal.pone.0150968 14 10 1 66 Humans|*Eosinophilic Esophagitis|thymic stromal lymphopoietin|Egg Hypersensitivity|*Cytokines|*Esophagus|*Cells, Epithelial|*Cell Differentiation|Eosinophils|*Cell Count|Epithelium|Cell Lines|Biopsies 54 EPSTI1 27533247 Oncotarget 2016 PMC5308675 10.18632/oncotarget.11202 10 10 0 50 Animals|*Vesicular Stomatitis|*Vesicular stomatitis Indiana virus|*Vesiculovirus|Oncolytic Viruses|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Oncolytic Virotherapy|*Pancreas|INCB018424|Pyrazoles|Interferon Type I|Cell Line, Tumor|Virus Replication|Protein Kinase Inhibitors|Signal Transduction|Antiviral Agents|2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide 37 EPSTI1 27186421 Am J Cancer Res 2016 PMC4859678 6 4 0 50 Humans|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Downregulation|EPSTI1 protein, human|*Neoplasm Proteins|MCF-7 Cells|*Disease Progression|Cell Line, Tumor|*Genes, Neoplasm|Lymphatic Metastasis|Cell Movement|Apoptosis|Biomarkers, Tumor|Cell Cycle|*Neoplastic Processes 37 EPSTI1 30444590 Vopr Onkol 2016 0 1 0 50 Humans|Male|*DNA Methylation|CpG Islands|*Prostate Cancer|Epigenesis, Genetic|EPSTI1 protein, human|Neoplasm Proteins|Epigenetic|Promoter Regions, Genetic|DNA Chip|Gene Expression Regulation, Neoplastic|KLF8 protein, human|Repressor Proteins 37 ERI3 27682269 Sci Rep 2016 PMC5041148 10.1038/srep34379 11 12 1 23 Humans|Animals|*Flavivirus|Dengue Virus|Dengue|Aedes|RNA, Viral|Virus Replication|*Golgi Apparatus|3' UTR|Cell Line|RNA-Binding Proteins 25 ERMN 27404287 Transl Psychiatry 2016 PMC5545709 10.1038/tp.2016.120 3 3 0 57 Humans|Male|*Autism Spectrum Disorder|Epigenesis, Genetic|DNA Methylation|*Epigenetic|Case-Control Study|Cohort Studies|*Protein Processing, Post-Translational|PDE10A protein, human|Phosphoric Diester Hydrolases|USP24 protein, human|Ubiquitin Thiolesterase 24 ERMN 26986762 Int. J. Mol. Med. 2016 PMC4829137 10.3892/ijmm.2016.2532 6 7 1 57 Female|Pregnancy|Rats|Humans|Animals|*Optic Nerve Injury|*Mesenchymal Stem Cells|*Fetal Blood|*Nerve Crush|*Axons|Mesenchymal Stem Cell Transplantation|Nerve Regeneration|Retinal Ganglion Cells|Optic Nerves|Growth Associated Protein 43|Stem Cells|*Placenta|*Peripheral Nerve Injuries|Cell Survival|*B Cells|Apoptosis|Crush Injuries|SRGAP2 protein, human 24 ESX1 27806942 Biol. Reprod. 2016 PMC5315426 10.1095/biolreprod.116.142273 16 2 0 100 Humans|Guinea Pigs|Female|Pregnancy|Animals|*Pre-Eclampsia|*Placenta|*Placental Insufficiency|Placental Development|Trophoblast|*Hypoxia|Fetal Growth Retardation|Hypertension 73 ETV3 27774448 Front Med (Lausanne) 2016 PMC5053979 10.3389/fmed.2016.00046 8 1 1 1655 *RNA Isoforms|*RNA-Seq|Sequence Analysis, RNA|*Psoriasis|Transcriptome|Splicings, Alternative|Gene Expression Profiling|*Whole Exome Sequencing|High-Throughput Nucleotide Sequencing 23 ETV7 27271568 J. Immunol. 2016 10.4049/jimmunol.1501032 10 14 0 205 Humans|Rats|Animals|*Pulmonary Surfactant-Associated Protein A|*Macrophages, Alveolar|NOS2 protein, human|Nitric Oxide Synthase Type II|Lipopolysaccharides|Macrophages|Pulmonary Surfactants|Interferon-gamma|Tumor Necrosis Factor-alpha|Cytokines|Nitric Oxide|Signal Transduction|Upregulation|Inflammation 43 ETV7 26805783 Am. J. Hum. Genet. 2016 PMC4746331 10.1016/j.ajhg.2015.12.003 24 0 1 205 Humans|*Genome-Wide Association Study|*Platelet Count|*Hispanic Americans|Alleles|Gene Frequency|Genetic Loci|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|European Continental Ancestry Group|Genotype|Platelets 43 EVX2 27553035 Neural Dev 2016 PMC4995821 10.1186/s13064-016-0070-1 3 0 1 14 Animals|*Spinal Cord|*Neurons|Zebrafish Proteins|Interneurons|Zebrafish|Transcription Factors|Homeodomain Proteins|Glutamic Acid|gamma-Aminobutyric Acid|Gene Expression Regulation, Developmental|PAX2 Transcription Factor|Glycine|Central Nervous System|Glutamate Decarboxylase|Neurotransmitter|Lmx1b protein, zebrafish 33 EVX2 26940624 Sci Rep 2016 PMC4778128 10.1038/srep22720 7 0 1 14 Animals|*Limb|Homeobox|Animal Fins|Body Patterning|Homeodomain Proteins|Genetic Evolution|Biological Evolution|Phylogeny|Gene Expression Regulation, Developmental|Zebrafish|Gene Cluster|Transcription Factors|Ray, Fish|Evx2 protein, zebrafish|Zebrafish Proteins 33 EVX2 26896392 Neural Dev 2016 PMC4759709 10.1186/s13064-016-0059-9 10 6 1 14 Animals|*PAX2 Transcription Factor|Transcription Factors|*Neurotransmitters|Homeodomain Proteins|Interneurons|Spinal Cord|Neurons|Zebrafish|Gene Expression Regulation, Developmental|gamma-Aminobutyric Acid|Glutamic Acid|In Situ Hybridization|Phenotype|evx1 protein, zebrafish|Zebrafish Proteins|Evx2 protein, zebrafish 33 EVX2 26883901 Sci Rep 2016 PMC4756668 10.1038/srep21111 3 0 1 14 Sheep|Animals|Mice|*Genome-Wide Association Study|*Phenotype|*Genome|Breeding|Chromosome Mapping|Linkage Disequilibrium|Genetic Association Studies|Genotype|SNPs|Horns|*Genomics|Haplotypes|Sheep, Domestic 33 FADS3 27865506 J. Dairy Sci. 2016 10.3168/jds.2016-11455 6 0 0 58 Female|Cattle|Animals|9,11-linoleic acid|*Linoleic Acids, Conjugated|11-octadecenoic acid|*Linoleic Acid|*Oleic Acids|Milk|*Ruminant|Goat|Lactation|Stearoyl-CoA Desaturase|Mammary Glands, Animal|*Isomerism|Fatty Acids|Diet|mRNA|*Catalysis 53 FADS3 27273350 J Nutr Health Aging 2016 10.1007/s12603-016-0720-3 6 0 0 58 Humans|*Erythrocyte Membrane|*Polyunsaturated Fatty Acids|Fatty Acid Desaturases|*Gene Cluster|Fatty Acids, Omega-3|Alleles|Polymorphism, Single Nucleotide|Genotype|Lipids|Erythrocytes|*Cognitive Impairment, Mild 53 FADS3 27269715 Prostaglandins Leukot. Essent. Fatty Acids 2016 10.1016/j.plefa.2016.03.009 8 1 0 58 Humans|Female|Animals|*Milk, Human|*Mothers|*Lactation|*Polyunsaturated Fatty Acids|Fatty Acid Desaturases|*Stearoyl-CoA Desaturase|*Chinese|Genetic Association Studies|Polymorphism, Single Nucleotide|Alleles|Genotype|Multigene Family 53 FADS3 27216536 Mol. Biol. Rep. 2016 PMC4949095 10.1007/s11033-016-4018-7 2 2 0 58 Mice|Animals|*Alternative Splicing|Fatty Acid Desaturases|Animals, Newborn|RNA, Messenger|Exon|Amino Acid Sequence|Gene Expression Regulation, Enzymologic|Eicosanoids|Isoenzymes|Liver|Species Specificity|Papio|Fads3 protein, mouse 53 FAIM3 27681387 Crit. Care Med. 2016 PMC5518756 10.1097/CCM.0000000000002021 19 0 0 72 *Benchmarking|*Sepsis|ROC Curve|*Gene Expression|Diagnosis, Differential|*Diagnostic Tests, Routine|Genes, Regulator 23 FAIM3 27385439 J. Neurochem. 2016 10.1111/jnc.13729 6 10 0 72 Mice|Animals|Neurodegenerative Diseases|FASLG protein, human|Fas Ligand|fas Receptor|Caspases|Apoptosis|XIAP protein, human|X-Linked Inhibitor of Apoptosis Protein|Receptors, Death Domain|Cell Death|Membrane Proteins|Nerve Tissue Proteins|Neurons|Endoplasmic Reticulum 23 FAM167A 27105348 Immunol. Invest. 2016 10.3109/08820139.2016.1157812 5 1 0 62 Humans|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|*Autoimmune Diseases|Gene Frequency|Case-Control Studies|src-Family Kinases|FAM167A-BLK protein, human|BLK protein, human 25 FAM167A 27088737 J Asthma 2016 10.3109/02770903.2015.1108437 3 0 0 62 Child|Humans|TNFSF4 protein, human|*OX40 Ligand|*Asian Continental Ancestry Group|*Allergic Rhinitis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Asthma|Gene Frequency|Haplotypes|Genetic Association Studies|*Risk Factors|Case-Control Studies|*Genes, src|FAM167A-BLK protein, human|BLK protein, human|src-Family Kinases 25 farp1 27617035 Epigenetics Chromatin 2016 PMC5018195 10.1186/s13072-016-0087-z 6 24 1 105 *Methylation|*Methyltransferases, Histone|KMT2D protein, human|*DNA-Binding Proteins|histone H3 trimethyl Lys4|Histone H3|*Promoter Regions, Genetic|Chromatin|*Neoplasm Proteins|Histone-Lysine N-Methyltransferase|Myeloid-Lymphoid Leukemia Protein|Lysine|Binding Sites|*Regulatory Sequences, Nucleic Acid|*Protein Processing, Post-Translational 26 farp1 27355516 Small GTPases 2016 PMC5464121 10.1080/21541248.2016.1202634 1 0 0 105 Humans|*Pheochromocytoma|*Adrenal Medulla|*Adrenal Gland Neoplasms|cdc42 GTP-Binding Protein|rac1 GTP-Binding Protein|rhoA GTP-Binding Protein|rho GTPases|RhoGEF|RAC1 protein, human 26 farp1 26911374 Endocr. Relat. Cancer 2016 10.1530/ERC-15-0502 9 2 1 105 Rats|Animals|Humans|*Pheochromocytoma|*ARHGEF1|*Adrenal Gland Neoplasms|cdc42 GTP-Binding Protein|rac1 GTP-Binding Protein|rho GTPase-activating protein|GTPase-Activating Proteins|rhoA GTP-Binding Protein|Adrenal Medulla|PC12 Cells|RAC1 protein, human|FARP1 protein, human|ARHGEF1 protein, human|Rac1 protein, rat 26 FASTK 27789713 J. Biol. Chem. 2016 PMC5207062 10.1074/jbc.M116.730291 3 0 0 83 Humans|*Genes, Mitochondrial|mitochondrial messenger RNA|mtRNA|mRNA|*Gene Expression Regulation|Mitochondrial Proteins|mRNA Translation|Mitochondria|Electron Transport Complex IV|RNA|RNA Stability|Protein-Serine-Threonine Kinases|HEK293 Cells|FASTKD2 protein, human|FASTKD3 protein, human 24 FASTKD2 27789713 J. Biol. Chem. 2016 PMC5207062 10.1074/jbc.M116.730291 3 0 0 49 Humans|*Genes, Mitochondrial|mitochondrial messenger RNA|mtRNA|mRNA|*Gene Expression Regulation|Mitochondrial Proteins|mRNA Translation|Mitochondria|Electron Transport Complex IV|RNA|RNA Stability|Protein-Serine-Threonine Kinases|HEK293 Cells|FASTKD2 protein, human|FASTKD3 protein, human 22 FASTKD2 27667664 Cell Metab. 2016 PMC5474757 10.1016/j.cmet.2016.08.017 52 7 0 49 Humans|*Oxidative Phosphorylation|*Clustered Regularly Interspaced Short Palindromic Repeats|RNA, Ribosomal, 16S|*Genome|Mitochondria|Mitochondrial Proteins|RNA, Mitochondrial|Protein Biosynthesis|RNA, Ribosomal|Cell Nucleus|Cell Line 22 FASTKD2 27501919 Biochem. Pharmacol. 2016 10.1016/j.bcp.2016.08.005 0 5 0 49 *Carcinoma, Hepatocellular|*Mitochondrial Proteins|Liver Neoplasms|Reactive Oxygen Species|Mitochondria|Cell Proliferation|Hep G2 Cells|Oxidative Stress|Apoptosis|Gene Expression Regulation, Neoplastic|*Cell Line|Dehydroepiandrosterone 22 FBXO45 28011490 Anticancer Res. 2016 10.21873/anticanres.11305 2 0 0 190 *Stomach Neoplasms|*Stomach|*Disease Progression|Kaplan-Meier Estimate|*Neoplastic Processes|Biomarkers, Tumor|RNA, Messenger|Prognosis 33 FBXO45 27526108 Oncogenesis 2016 PMC5007829 10.1038/oncsis.2016.55 4 1 1 190 *Epithelial-Mesenchymal Transition|Transcription Factors|Zinc Finger E-box-Binding Homeobox 1|Homeodomain Proteins|Gene Expression Regulation, Neoplastic|Cadherins|Cell Line, Tumor|Transforming Growth Factor beta|Apoptosis Regulatory Proteins 33 FCGBP 27817035 J. Assist. Reprod. Genet. 2016 PMC5330977 10.1007/s10815-016-0822-1 2 0 0 24 Humans|Female|*DNA Copy Number Variations|*Endometriosis|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome, Human|Genetic Loci|Gene Frequency|Genotype 63 FCGBP 27350034 Mol. Psychiatry 2016 10.1038/mp.2016.94 10 0 0 24 Humans|*Bipolar Disorder|*Gene Regulatory Networks|Genome-Wide Association Study|*Transcriptome|Single Nucleotide Polymorphisms|*Whole Exome Sequencing|Genetic Predisposition to Disease|Gene Expression Profiling|Brain|Phenotype|*Gray Matter|Signal Transduction|Energy Metabolism 63 FCGBP 27340863 Oncotarget 2016 PMC5312295 10.18632/oncotarget.10175 12 0 1 24 Humans|*Neoplastic Cells, Circulating|*Liver Neoplasms|*Cell Count|Colorectal Neoplasms|*Colonic Neoplasms|*Rectal Neoplasms|*Intestine, Large 63 FCGBP 27189557 Mol. Biol. Evol. 2016 PMC4948705 10.1093/molbev/msw066 26 0 1 24 Animals|*Mucins|*Mucus|*Genetic Evolution|Mucin-5B|Mucin-6|Mucin-2|Amino Acid Sequence|Phylogeny|Genome|Ovomucin|Cells, Epithelial|Xenopus|Zebrafish 63 FCGRT 27900359 Cold Spring Harb Mol Case Stud 2016 PMC5111006 10.1101/mcs.a001032 3 3 1 1208 Humans|Male|Aged|*Homozygote|Checkpoint Kinase 2|Genetic Predisposition to Disease|Germ-Line Mutation|Mutations|Pedigree|Neoplastic Syndromes, Hereditary|Siblings 45 FCGRT 27769251 BMC Cancer 2016 PMC5073891 10.1186/s12885-016-2851-7 13 7 1 1208 *Carcinoma, Hepatocellular|*Liver Neoplasms|Prognosis|*Disease Progression|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|MicroRNAs|Kaplan-Meier Estimate|Cell Proliferation|Cell Line, Tumor 45 FCGRT 27312193 Clin Pharmacokinet 2016 10.1007/s40262-016-0406-3 4 0 0 1208 Humans|*Bevacizumab|*Progression-Free Survival|Angiogenesis Inhibitors|Leucovorin|Colorectal Neoplasms|Fluorouracil|Antibodies, Monoclonal, Humanized|Disease-Free Survival|Antineoplastic Combined Chemotherapy Protocols|Vascular Endothelial Growth Factor A|Organoplatinum Compounds|Kaplan-Meier Estimate|*Rectal Neoplasms|*Colonic Neoplasms 45 FCGRT 27481246 Infect. Immun. 2016 PMC5038074 10.1128/IAI.00533-16 6 9 1 1208 Mice|Animals|Fc receptor, neonatal|*Fc Receptor|*Histocompatibility Antigens Class I|Immunity|Immunoglobulin G|*Tuberculosis|alpha E integrins|*Integrin alpha Chains|*Lung|Protein Binding|Neutrophils|*Antigens, CD|Dendritic Cells 45 FCGRT 27384673 Oncotarget 2016 PMC5342352 10.18632/oncotarget.10074 8 4 0 1208 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Down-Regulation|Fc receptor, neonatal|*Histocompatibility Antigens Class I|*Fc Receptor|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|mRNA|Real-Time Polymerase Chain Reaction 45 FCGRT 26840762 Pediatr Int 2016 10.1111/ped.12823 0 0 0 1208 Humans|BTK protein, human|*Agammaglobulinaemia Tyrosine Kinase|Eosinophilic enteropathy|Agammaglobulinemia|*Enteritis|*Gastritis|*Eosinophilia|Protein-Tyrosine Kinases|Genetic Linkage|Mutation|X Chromosome 45 FCRL1 27193470 Rheumatol. Int. 2016 10.1007/s00296-016-3495-2 2 0 0 2 Humans|FCRL2 protein, human|Receptors, Cell Surface|FCRL1 protein, human|*Membrane Proteins|*Rheumatoid Arthritis|FCRL4 protein, human|Fc Receptor|*Gene Expressions|B-Lymphocytes|Leukocytes, Mononuclear|mRNA|Immunoglobulins 34 Fcrla 27887572 BMC Genomics 2016 PMC5124223 10.1186/s12864-016-3310-1 21 6 0 38 Pregnancy|Humans|Child|Female|Infant, Newborn|Cohort Studies|*Epigenesis, Genetic|CpG Islands|Maternal Exposure|DNA Methylation|Cotinine|Prenatal Exposure Delayed Effects|Smoking|Fetal Blood|Genome-Wide Association Study|Tobacco Smoking|Mother|Norway 27 Fcrla 27015273 PLoS ONE 2016 PMC4807760 10.1371/journal.pone.0152425 6 2 1 38 Humans|*HIV-1|*Fc Receptors|FCGR2A protein, human|*Receptors, IgG|Fc gamma receptor IIC|AIDS Vaccines|*HIV Seropositivity|HIV Infections|*B Cells|*Gene Expression Regulation|Single Nucleotide Polymorphisms|Gene Expression|Thailand|FCGR2C protein, human 27 Fcrla 27008852 Toxicol. Sci. 2016 PMC4914802 10.1093/toxsci/kfw032 2 0 0 38 Humans|*Imatinib Mesylate|*Haploidy|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|Antineoplastic Agents|Drug Resistance, Neoplasm|Protein Kinase Inhibitors|Piperazines|Pyrimidines|Benzamides|Cell Proliferation|Apoptosis|Cell Line, Tumor|Cell Survival|Mutation|*Formaldehyde|Genomics 27 Fcrla 26980576 J. Rheumatol. 2016 10.3899/jrheum.150665 2 0 0 38 *Lupus Nephritis|*Cyclophosphamide|Immunosuppressive Agents|Azathioprine|*Administration, Intravenous|*Infusions, Intravenous|FCGR2B protein, human|*Receptors, IgG|*Polymorphism, Genetic 27 FERD3L 27528042 Int. J. Dev. Biol. 2016 10.1387/ijdb.160232nb 3 0 0 19 Pregnancy|Female|Mice|Animals|*Ependyma|Transcription Factor|Neural Tube|Neurogenesis|Spinal Cord|Nerve Tissue Proteins|Mesencephalon|Cell Differentiation|Gene Expression Regulation, Developmental|Hedgehog Proteins|Neurons|Central Nervous System|Ferd3l protein, mouse 21 fes1 27782493 J Chem Phys 2016 10.1063/1.4964651 0 0 0 198 *Photoelectron Spectroscopy|ferrous sulfide|*Density Functional Theory|*Sulfides|*Ferrous Compounds|*Anions|Quantum Theory|Molecular Structure|Iron 35 fes1 28773328 Materials (Basel) 2016 PMC5456699 10.3390/ma9030200 2 4 0 198 *Corrosion|*Chromium|*Steels|*Temperature|Chromium Alloys|Surface Properties|Stainless Steel|Materials Testing|Saliva, Artificial|Nickel|Oxides|*Hot Temperature 35 fes1 26912797 Mol. Biol. Cell 2016 PMC4831876 10.1091/mbc.E15-10-0697 12 11 1 198 *Saccharomyces cerevisiae|*Cytosol|*HSP70 Heat-Shock Proteins|Saccharomyces cerevisiae Proteins|Proteasome|Ubiquitin|*Yeast, Dried|Molecular Chaperones|HSP40 Heat-Shock Proteins|Proteolysis|Protein Folding|Adenosine Triphosphatases|Cell Nucleus|Ubiquitin-Protein Ligases|Cytoplasm|*Isoforms|*Nucleotides|FES1 protein, S cerevisiae 35 FGL1 27732889 Int. J. Biochem. Cell Biol. 2016 10.1016/j.biocel.2016.10.008 1 1 0 118 Male|Proteomics|Epididymis|TYRP1 protein, human|*Membrane Glycoproteins|Spermatozoa|FGL2 protein, human|*Fibrinogen|Blotting, Northern|Blotting, Western|In Situ Hybridization|Amino Acid Sequence|*Hemostatics|*Protein Domains|IgA receptor|Disulfides 50 FGL1 27221093 Diabetologia 2016 10.1007/s00125-016-3991-7 4 3 0 118 *Insulin Resistance|*Diabetes Mellitus, Type 2|Glucose Intolerance|Prediabetic State|Glucose Tolerance Test|Blood Glucose|Fasting|Nonalcoholic Fatty Liver Disease 50 FGL1 27007659 PLoS ONE 2016 PMC4805164 10.1371/journal.pone.0152047 11 0 1 118 Humans|Aged|*Whole Exome Sequencing|Basal Laminar Drusen|*Retinal Drusen|*Age Related Macular Degeneration|*Bruch Membrane|*Eye Diseases, Hereditary|Complement Factor H|Heterozygote|Pedigree|Polymorphism, Single Nucleotide|Age-at-Onset|EFEMP1 protein, human|Extracellular Matrix Proteins|FBLN5 protein, human 50 FGL1 26976764 J Ethnopharmacol 2016 10.1016/j.jep.2016.03.029 2 0 0 118 Rats|Animals|*Proteomics|yinchenwuling|*Drugs, Chinese Herbal|Electrophoresis, Gel, Two-Dimensional|Traditional Chinese Medicine|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|*Powders 50 FILIP1L 27776341 Oncotarget 2016 PMC5340232 10.18632/oncotarget.12784 3 20 0 87 Humans|Female|Mice|Animals|*Wnt Signaling Pathway|*Drug Resistance, Neoplasm|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|beta Catenin|Epithelial-Mesenchymal Transition|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Up-Regulation|FILIP1L protein, human|Intracellular Signaling Peptides and Proteins 44 FILIP1L 27570103 Theriogenology 2016 10.1016/j.theriogenology.2016.07.021 0 0 0 87 Humans|Horses|Male|Animals|*Down-Regulation|progonadoliberin I|Gonadorelin|Luteinizing Hormone|Testosterone|Follicle Stimulating Hormone|Sperm Count|estrone sulfate|Estrone|Testis|acyline|Oligopeptides|*Hormone Antagonists|Sperm|Sexual Behavior, Animal|Ejaculation 44 FILIP1L 27750216 Oncotarget 2016 PMC5342157 10.18632/oncotarget.12664 4 39 0 87 Humans|*Filamins|Glycogen Synthase Kinase 3|*Colorectal Cancer|*Disease Progression|Proto-Oncogene Proteins c-akt|Cell Proliferation|HCT 116 Cells|Prognosis|beta Catenin|Signal Transduction|Apoptosis|Phosphorylation|Cell Cycle Arrest|Lymphatic Metastasis|Carcinogenesis|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic 44 FILIP1L 27353360 Nat Commun 2016 PMC4931344 10.1038/ncomms12037 13 54 1 87 *HSP90 Heat-Shock Proteins|*Molecular Chaperone|Kidney Neoplasms|Tumor Suppressor Proteins|Phosphorylation 44 FILIP1L 26887440 FASEB J. 2016 10.1096/fj.201500135 6 5 0 87 Humans|Fluticasone Propionate Salmeterol|*Chronic Obstructive Lung Disease|Bronchodilator Agents|Adrenergic beta-2 Receptor Agonists|*Adrenal Cortex Hormones|Administration, Inhalation|Forced Expiratory Volume|Glucocorticoids|*Immunoglobulin|*B Cells 44 FJX1 28030623 PLoS ONE 2016 PMC5193488 10.1371/journal.pone.0169127 2 0 0 72 Animals|*Genome-Wide Association Study|*Carps|Prospective Studies|*Phenotype|*Abdominal Fat|Quantitative Trait Loci|*Muscle|Polymorphism, Single Nucleotide|Body Weight 26 FKBP11 27689402 Oncotarget 2016 PMC5342102 10.18632/oncotarget.12257 7 9 0 61 Animals|Humans|*Zebrafish|Endothelial Cells|Animal Fins|Zebrafish Proteins|Regeneration|*Wound Healing|Cell Differentiation|Gene Expression Regulation, Developmental|neuronectin|Extracellular Matrix Proteins|Gene Expression|FN1 protein, human|Fibronectins|Extracellular Matrix|*In Silico|Nerve Tissue Proteins|Melanoma|FKBP10 protein, human 21 FKBP11 27039902 Diabetologia 2016 10.1007/s00125-016-3947-y 25 2 0 61 Mice|Animals|Diabetes Mellitus, Type 2|*Unfolded Protein Response|*Endoplasmic Reticulum|Insulin-Secreting Cells|*Cell Death|Transcription Factor CHOP|Endoplasmic Reticulum Stress|DNA-Binding Proteins|Transcription Factors|X-Box Binding Protein 1|Apoptosis|*Hypoxia|Regulatory Factor X Transcription Factors|*Cell Movement|Cell Line|*Protein Transport 21 FKBP11 26735435 Autophagy 2016 PMC4835210 10.1080/15548627.2015.1117734 40 3 0 61 Humans|*Epigenesis, Genetic|Histone|Polycomb Repressive Complex 2|Enhancer of Zeste Homolog 2 Protein|Histone Methyltransferases|DNA-Binding Proteins|Downregulation|*Genes, Regulator|RNA Interference|Promoter Regions, Genetic|Binding Protein|*Autophagy|TOR Serine-Threonine Kinases|EZH2 protein, human|MTOR protein, human 21 FMN1 27554456 SLAS Discov 2016 10.1177/1087057116664029 0 0 0 3571 Humans|*Purpura, Thrombocytopenic, Idiopathic|IL10 protein, human|Interleukin-10|Tumor Necrosis Factor-alpha|*Gene Expression|Cytokines|*Thrombocytopenia 42 FMN1 27151647 Addict Biol 2016 10.1111/adb.12402 7 0 0 3571 *Alcoholism|Genome-Wide Association Study|*Epistasis, Genetic|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Phenotype|*Substance Dependence|Genotype|*Comorbidity|Marijuana Dependence 42 FMN1 26836166 J. Alzheimers Dis. 2016 10.3233/JAD-150769 1 0 0 3571 *Neurodegenerative Diseases|*Computational Biology|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|Network, Gene|Parkinson Disease|Alzheimer Disease, Late Onset|Genetic Predisposition to Disease|MEDLINE 42 FMN2 27912053 Cell 2016 10.1016/j.cell.2016.11.024 0 0 0 123 *Formins|Actin Cytoskeleton|*Cell Nucleus|Microfilament Proteins|Actins|Cell Movement|Nuclear Proteins 63 FMN2 27839864 Cell 2016 PMC5135586 10.1016/j.cell.2016.10.023 22 24 0 123 Humans|Mice|Animals|*Actins|*Cell Nucleus|Microfilament Proteins|Focal Adhesion|Actin Cytoskeleton|Cytoskeleton|Cell Movement|Nuclear Proteins|*Neoplastic Processes|Formins|Cell Adhesion|Tumor Microenvironment 63 FMN2 27789627 Development 2016 PMC5201043 10.1242/dev.139295 7 0 0 123 *Wnt Signaling Pathway|FLNA protein, human|*Filamins|*Formins|Glycogen Synthase Kinase 3|Low Density Lipoprotein Receptor-Related Protein-6|Wnt Proteins|*Endocytosis|beta Catenin|Cell Differentiation|Cell Proliferation|Cell Polarity|Phosphorylation 63 FNDC1 27693493 Exp. Cell Res. 2016 PMC5077722 10.1016/j.yexcr.2016.09.021 16 25 0 16 Humans|Male|AR protein, human|*Receptors, Androgen|FN1 protein, human|*Fibronectins|*Prostate Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Apoptosis|Signal Transduction|FNDC1 protein, human|Neoplasm Proteins|MIRN1207 microRNA, human 29 FNDC1 27677580 Nat Commun 2016 PMC5052699 10.1038/ncomms12792 16 4 1 16 Child|Humans|*Genome-Wide Association Study|*Otitis Media|Anti-Bacterial Agents|FNDC1 protein, human|Neoplasm Proteins 29 FNDC1 27064407 PLoS ONE 2016 PMC4827815 10.1371/journal.pone.0151399 5 9 1 16 Humans|Rats|Animals|*Fibronectin Type III Domain|*Hypertension|Blood Pressure|Rats, Inbred Dahl|Quantitative Trait Loci|*Proteins|Signal Transduction|Mutations|Blood Pressure Determination|FNDC1 protein, human|Neoplasm Proteins 29 FNDC1 26826188 J. Cell. Sci. 2016 10.1242/jcs.181883 5 8 0 16 Rats|Animals|*Vascular Endothelial Growth Factor A|Endothelial Cells|*Signal Transduction|KDR protein, human|Vascular Endothelial Growth Factor Receptor-2|*G Protein|*Neovascularization, Pathologic|*Vascular Endothelial Growth Factors|Cell Movement|Phosphorylation|Intracellular Signaling Peptides and Proteins|Neovascularization, Physiologic|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Cell Proliferation|MAPK, p38|RNA, Small Interfering 29 FNDC1 26762409 Tumour Biol. 2016 10.1007/s13277-015-4629-y 14 2 1 16 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*Fibroblasts|Cancer-Associated Fibroblasts|*Extracellular Matrix|TGFB1 protein, human|Transforming Growth Factor beta1|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Type I Collagen|Upregulation|STC2 protein, human|Glycoproteins|Intercellular Signaling Peptides and Proteins|FNDC1 protein, human|Neoplasm Proteins 29 FNIP1 27506764 EMBO Mol Med 2016 PMC5048369 10.15252/emmm.201606372 12 17 1 189 Mice|Animals|*AMP-Activated Protein Kinases|*mdx Mouse|*Muscle Fibers, Skeletal|Slow-Twitch Muscle Fiber|Muscle Fibers, Fast-Twitch|*Mitochondria|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Muscle Contraction|Muscle, Skeletal|Oxidation-Reduction|Duchenne Muscular Dystrophy|Signal Transduction|Myosin Heavy Chains|Transcription Factors|MicroRNAs|FNIP1 protein, mouse|Carrier Proteins 44 FNIP1 27353360 Nat Commun 2016 PMC4931344 10.1038/ncomms12037 13 54 1 189 *HSP90 Heat-Shock Proteins|*Molecular Chaperone|Kidney Neoplasms|Tumor Suppressor Proteins|Phosphorylation 44 FNIP1 27303042 Proc. Natl. Acad. Sci. U.S.A. 2016 PMC4932993 10.1073/pnas.1607592113 14 0 0 189 Humans|Mice|Animals|*AMP-Activated Protein Kinases|Birt-Hogg-Dube Syndrome|FLCN protein, human|Tumor Suppressor Proteins|Proto-Oncogene Proteins|Kidney Neoplasms|*Mutation|Carrier Proteins|Phosphorylation|B Cells|*Cardiomyopathy|FNIP1 protein, mouse 44 foxd4 27092474 Genesis 2016 PMC4912902 10.1002/dvg.22943 10 21 1 58 Humans|Mice|Animals|*Ectoderm|*Blastomeres|Neural Plate|Xenopus laevis|Xenopus Proteins|*Nervous System|Blastula|Gastrula|Gene Expression Regulation, Developmental|Activation, Transcriptional|Cell Differentiation|Zygotes|Forkhead Transcription Factors|Signal Transduction|3'-(1-butylphosphoryl)adenosine 27 FOXI3 27495896 Toxicol. Appl. Pharmacol. 2016 10.1016/j.taap.2016.08.001 7 3 0 37 Pregnancy|Female|Mice|Animals|*Diethylhexyl Phthalate|Plasticizers|Prenatal Exposure Delayed Effects|Maternal-Fetal Exchange|Reproduction|Ovarian Follicle|Ovary|Lactation|Forkhead Box Protein L2|Estrogens 30 FOXI3 26992132 Stem Cells 2016 PMC5287380 10.1002/stem.2363 13 7 0 37 Dogs|Mice|Animals|*Hair Follicle|Stem Cells|Hair|Stem Cell Niche|Transcription Factor, SOX-9|Gene Expression Regulation|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Cell Proliferation|Homeostasis|Lhx2 protein, mouse|Transcription Factors|LIM-Homeodomain Proteins|Foxi3 protein, mouse|Forkhead Transcription Factors 30 FOXJ3 27739607 Mol. Reprod. Dev. 2016 10.1002/mrd.22750 2 0 0 127 Mice|Male|Animals|Humans|*Knockout Mouse|*Spermatogenesis|Spermatocytes|Spermatogonia|Sertoli Cells|Meiosis|Transcription Factor|Male Sterility|FoxJ3 protein, human|Cell Cycle Proteins|Forkhead Transcription Factors|FoxJ3 protein, mouse|DNA-Binding Proteins 21 FOXJ3 27073521 Oncol Lett 2016 PMC4812169 10.3892/ol.2016.4269 0 0 0 127 Humans|*Prognosis|*Colorectal Cancer|*Cell Migration|MicroRNAs|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|*Neoplastic Processes|*Colonic Neoplasms|Disease Progression 21 FOXJ3 26849429 PLoS ONE 2016 PMC4746119 10.1371/journal.pone.0148532 6 17 1 127 *Organelle Biogenesis|DNA-Binding Proteins|*Myocytes|Transcription Factors|Mitochondria|Mitochondrial Proteins|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|MicroRNAs|Downregulation|Gene Expression Regulation|Nuclear Respiratory Factor 1|Cell Differentiation|Myogenesis|DNA, Mitochondrial|Signal Transduction|3' Untranslated Region|mRNA 21 FOXN2 26962893 Nucleus 2016 PMC4916893 10.1080/19491034.2016.1150392 6 34 1 138 28 FOXN4 27864379 Development 2016 PMC5201034 10.1242/dev.143859 14 3 0 65 Animals|*Cilia|Xenopus laevis|Xenopus Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Forkhead Transcription Factors|Mucociliary Clearance|*Gene Expression|FOXN4 protein, Xenopus|GEMC1 protein, Xenopus 54 FOXN4 27343557 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.06.088 4 0 0 65 Animals|*Zebrafish|*Mediator Complex|*Hyaluronan Synthases|Zebrafish Proteins|*Organogenesis|Brachyury protein|T-Box Domain Proteins|Cardiac Valve|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Fetal Proteins|tbx2b protein, zebrafish|has2 protein, zebrafish 54 FOXN4 26839365 Development 2016 PMC4813337 10.1242/dev.129254 16 0 0 65 Mice|Animals|Interneurons|Spinal Cord|Neurogenesis|Eye Proteins|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Motoneurons|Gene Expression Regulation, Developmental|GATA2 protein, human|GATA2 Transcription Factor|Ependyma|Forkhead Transcription Factors|Pkd2l1 protein, mouse|Receptors, Cell Surface|Calcium Channels 54 FRMD4A 27666346 Int. J. Mol. Med. 2016 PMC5065292 10.3892/ijmm.2016.2745 2 8 1 33 Humans|*Tongue Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Cell Cycle|RNA, Small Interfering|Carcinoma, Squamous Cell|Cell Proliferation|Cell Movement|Cell Line, Tumor|RNA Interference|Lymphatic Metastasis|Gene Expression Regulation, Neoplastic|mRNA|Cell Cycle Arrest|Transfections|Head and Neck Neoplasms 26 FRMD4A 27564456 Epigenetics 2016 PMC5094634 10.1080/15592294.2016.1226451 19 4 0 33 Humans|Genome-Wide Association Study|*DNA Methylation|*Chronic Obstructive Pulmonary Disease|*Lung|Smoking|Quantitative Trait Loci|Epigenetic|Genetic Predisposition to Disease|Genetic Association Studies|Genomics|Transcription Factors 26 FRMD4A 27171005 PLoS ONE 2016 PMC4865176 10.1371/journal.pone.0155554 23 14 1 33 Pregnancy|Female|Child|Humans|United States|Child, Preschool|*DNA Methylation|*Pediatric Obesity|*Epigenome|CpG Islands|Epigenesis, Genetic|Maternal Exposure|Prenatal Exposure Delayed Effects|Genome-Wide Association Study|Smoking|Fetal Blood|Smoking, Tobacco|Smoke|CNTNAP2 protein, human|Nerve Tissue Proteins|Membrane Proteins|DNA 26 FRMD4A 27103528 Neurobiol. Aging 2016 10.1016/j.neurobiolaging.2016.02.016 11 0 1 33 *Risk Factors|Australia|*Cognitive Decline|Alzheimer Disease, Late Onset|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Genome-Wide Association Study|Episodic Memory 26 FRMD4A 27044754 J. Cell. Sci. 2016 10.1242/jcs.180745 6 3 1 33 Humans|HEK293 Cells|Alzheimer Disease|tau Proteins|*Cell Signaling|Neurons|Phosphorylation|ADP-ribosylation factor 6|ADP-Ribosylation Factors|Brain|Upregulation|Guanine Nucleotide Exchange Factors|Neurogenesis|RNA Interference 26 FRMD4A 26893625 Exp Ther Med 2016 PMC4734186 10.3892/etm.2015.2933 1 2 1 33 Humans|*FERM Domains|*Rectal Cancer|Immunohistochemistry|Lymphatic Metastasis|Prognosis|Stomach Neoplasms|CDH1 protein, human|Cadherins|mRNA|Real-Time Polymerase Chain Reaction|Western Blotting|Antigens, CD 26 FXYD5 27716384 J Transl Med 2016 PMC5050926 10.1186/s12967-016-1038-y 15 0 1 129 Port-Wine Stain|*Vascular Malformations|*Neoplasms|Neovascularization, Pathologic|Ion Channels 81 FXYD5 27682981 J. Cell. Physiol. 2016 10.1002/jcp.25622 14 4 0 129 Humans|*Epithelial-Mesenchymal Transition|HEK293 Cells|CDH1 protein, human|*E-Cadherin|*Antigens, CD|Transcription Factors|Snail Family Transcription Factors|Cell Motility|Vimentin|Neoplasm Invasiveness|Tumor Cell Lines|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Adhesion|Transcription, Genetic|*RNA Splicing|mRNA|Promoter Regions, Genetic 81 FXYD5 27142834 J. Cell. Sci. 2016 PMC4920254 10.1242/jcs.186148 8 4 0 129 *Sodium-Potassium-Exchanging ATPase|*Glycosylation|*Dimerization|Plasma Membrane|*Sodium|Signal Transduction|Protein Subunits|Protein Binding|Epithelial Cells|Binding Sites 81 FXYD5 27066483 Front Cell Dev Biol 2016 PMC4812908 10.3389/fcell.2016.00026 6 17 1 129 *Sodium-Potassium-Exchanging ATPase|Membrane Protein|Membrane Glycoproteins|Neoplasm Proteins|Cell Adhesion|Cell Line, Tumor 81 FXYD5 27006401 J. Biol. Chem. 2016 PMC4900257 10.1074/jbc.M115.699041 3 4 0 129 Mice|Animals|Sodium-Potassium-Exchanging ATPase|TYRP1 protein, human|*Membrane Glycoproteins|Membrane Proteins|*Cells, Epithelial|Neoplasm Proteins|Cell Line, Tumor|CCL2 protein, human|Chemokine CCL2|Transfection|Lung|Sodium|*Cell Count|FXYD5 protein, mouse 81 FXYD5 26898779 Neuron 2016 PMC4790095 10.1016/j.neuron.2016.01.034 79 4 3 129 Animals|Axons|Nerve Regeneration|Ganglia, Dorsal Root|Neurons|Peripheral Nervous System|Cells, Cultured 81 GABRG1 27355804 Pharmacogenomics 2016 10.2217/pgs-2016-0020 5 0 0 26 *Polymorphism, Single Nucleotide|*Smoking|Tobacco Use Disorder|Smoking Cessation|*Tobacco Smoking|Genetic Association Studies|Receptors, Nicotinic|Gene Frequency|Alleles|Nerve Tissue Proteins|Mexico 48 GABRG1 26884404 Comp. Med. 2016 PMC4752030 1 1 0 26 Male|Rats|Animals|*Rats, Inbred F344|*Social Isolation|*Weaning|*Hippocampus|Receptors, Kainate|Receptors, AMPA|Receptors, N-Methyl-D-Aspartate|GABA A Receptor|Glutamic Acid|Neurons|Cells, Pyramidal|gamma-Aminobutyric Acid|Synapses|Aspartate 48 GABRP 27750143 Psychoneuroendocrinology 2016 10.1016/j.psyneuen.2016.10.001 5 0 0 19 Humans|Male|Animals|Rats|*Finasteride|*Nucleus Accumbens|*Proteomics|5-alpha Reductase Inhibitors|Rats, Sprague-Dawley|Schizophrenia|Reflex, Startle|Brain|Benign Prostatic Hyperplasia|PRPS1 protein, human|Ribose-Phosphate Pyrophosphokinase|GABRP protein, human|Receptors, GABA-A 40 GABRP 27222045 Int. J. Mol. Med. 2016 10.3892/ijmm.2016.2597 0 6 0 19 Humans|Adult|Animals|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*MAP Kinase Signaling System|*GABA|Mitogen-Activated Protein Kinases|Cell Proliferation|Apoptosis|Cell Line, Tumor|GABA A Receptor|MAPK, p38|Signal Transduction|mRNA|GABRP protein, human 40 GABRP 27221053 Int. J. Mol. Med. 2016 PMC4899026 10.3892/ijmm.2016.2608 4 16 1 19 Humans|Animals|Mice|Female|Pregnancy|*Trophoblasts|*Pre-Eclampsia|*Receptors, GABA-A|*Apoptosis|Placenta|Placentation|Cell Proliferation|Cell Movement|Cell Line|RNA, Messenger|GABRP protein, human 40 GAGE1 27776018 Melanoma Res. 2016 10.1097/CMR.0000000000000308 2 0 0 20 Humans|Melanoma, Cutaneous Malignant|Melanoma|Multidrug Resistance|Drug Resistance, Neoplasm|ATP-Binding Cassette Transporters|ATP Binding Cassette Transporter, Subfamily B, Member 1|Skin Neoplasms|Cell Line, Tumor|ATP Binding Cassette Transporter, Subfamily B|Cisplatin|Neoplastic Stem Cells|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|*DNA 48 GAGE1 26885621 Oncotarget 2016 PMC4924690 10.18632/oncotarget.7359 9 4 1 20 Humans|Male|*Prostate|*Cancer Biomarkers|Proteomics|Early Detection of Cancer|*Prostate Cancer|Prostate-Specific Antigen|Benign Prostatic Hyperplasia|Antigens, Neoplasm|*African Continental Ancestry Group|Autoantibodies|*Cohort Studies|Africa 48 GBX1 27657450 Neuron 2016 PMC5319854 10.1016/j.neuron.2016.08.020 24 1 0 17 Mice|Animals|*GABAergic Neurons|*Gene Regulatory Networks|NKX2-1 protein, human|*Thyroid Nuclear Factor 1|LIM-Homeodomain Proteins|Transcription Factors|Homeodomain Proteins|Interneurons|*Genes, Homeobox|Nuclear Proteins|*Prosencephalon|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Medial Eminence|Cell Differentiation|Cell Movement|Embryo, Mammalian|Mice, Transgenic 34 GBX1 27396829 Structure 2016 PMC5109927 10.1016/j.str.2016.05.013 0 0 0 17 Protein Conformation, beta-Strand|Protein Conformation, alpha-Helical|Binding Sites|Protein Binding|Cloning, Molecular|Simulations, Molecular Dynamics|Protein Interaction Domains and Motifs|Amino Acid Sequence|Gene Expression|Sequence Alignment|Nuclear Magnetic Resonance, Biomolecular|DNA|Thermodynamics|Escherichia coli|Sequence Homology, Amino Acid|*Biochemical Phenomena|Genetic Vectors|*DNA-Binding Proteins 34 GCNT2 27936067 PLoS ONE 2016 PMC5147899 10.1371/journal.pone.0167562 3 1 0 20 37 GCNT2 27609212 BMC Med. Genet. 2016 PMC5016880 10.1186/s12881-016-0316-0 5 0 1 20 37 GCNT2 27600951 Transfusion 2016 10.1111/trf.13796 2 0 0 20 37 GCNT2 27020340 Future Oncol 2016 10.2217/fon.16.22 3 0 0 20 37 GLDN 27616481 Am. J. Hum. Genet. 2016 PMC5065655 10.1016/j.ajhg.2016.07.021 9 2 0 88 Humans|*Ranvier's Nodes|*Arthrogryposis|Axons|Cell Adhesion Molecules, Neuronal|Cell Adhesion Molecules|Myelin Sheath|Schwann Cells|*Mutations|Neuroglia|Nerve Growth Factors|Nerve, Sciatic|Cell Membrane|Whole Exome Sequencing|Cell Adhesion|GLDN protein, human|Membrane Proteins|Nerve Tissue Proteins 30 GLIPR2 26972116 Amyotroph Lateral Scler Frontotemporal Degener 2016 10.3109/21678421.2016.1143012 3 0 0 52 Humans|Adult|Amyotrophic Lateral Sclerosis 2, Juvenile|*Amyotrophic Lateral Sclerosis|RNA-Binding Protein FUS|*Mutations|Superoxide Dismutase-1|*Chinese|Genetic Testing|Genetic Association Studies|Genetic Predisposition to Disease|Superoxide Dismutase|Ribonuclease, Pancreatic|DNA-Binding Proteins|SETX protein, human|RNA Helicases|SPG11 protein, human|Proteins|C9orf72 protein, human|C9orf72 Protein 21 glycolisis 26876611 J. Biotechnol. 2016 10.1016/j.jbiotec.2016.02.015 0 0 0 0 *Arabidopsis|*Plants, Transgenic|*Helianthus|*Transcription Factor|*Biomass|Leucine Zipper|Arabidopsis Proteins|Gene Expression Regulation, Plant|Plant Proteins|*Floods|Homeodomain Proteins|Droughts|Plant Leaves|Genes, Plant|Promoter Regions, Genetic|Seeds|Stress, Physiological 23 glycolisis 30198655 Tsitologiia 2016 0 2 0 0 *Glycolysis|Pyruvate|Transcription Factor|*Phenotype|*Hypoxia|Lactate|Gene Expression Regulation|Cell Line, Tumor|Lactate Dehydrogenase|Gene Expression 23 glycosis 27908734 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.11.156 5 4 0 0 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Triose-Phosphate Isomerase|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|shRNA|Vimentin|beta Catenin|Cell Cycle|Hep G2 Cells|RNA Interference|Down-Regulation|Neoplasm Transplantation|Cell Line, Tumor|Cell Cycle Arrest|Tumor Burden 21 GMFB 27655328 PLoS ONE 2016 PMC5031439 10.1371/journal.pone.0161491 6 0 1 125 Neoplasm Recurrence, Local|MicroRNAs|Carcinoma, Non-Small-Cell Lung|Gene Expression Regulation, Neoplastic|Lung Neoplasms|Cell Proliferation|Cell Movement|Downregulation|Gene Expression Profiling|Apoptosis|Signal Transduction|Cell Transformation, Neoplastic 26 GOLGA3 28959563 Toxicol Rep 2016 PMC5615912 10.1016/j.toxrep.2016.03.009 0 4 0 189 Male|Female|Rats|Animals|*Acrylamide|*Drinking Water|*Animals, Newborn|*Transcriptome|*Rats, Wistar|Signal Transduction 46 GPR174 27211051 Front Horm Res 2016 10.1159/000443871 0 0 0 18 *Addison Disease|*Genetic Predisposition to Disease|HLA DRB1|Allele|Polymorphism, Genetic|Genes, HLA Class II|CTLA4 protein, human|Cytotoxic T-Lymphocyte Antigen 4|Polyendocrinopathies, Autoimmune|STAT4 Transcription Factor|MHC class I-related chain A|Histocompatibility Antigens Class I|MHC class II transactivator protein|Nuclear Proteins|Trans-Activators 26 GPR174 27077565 J. Med. Chem. 2016 10.1021/acs.jmedchem.5b01925 2 0 0 18 Humans|lysophosphatidylserine|*Glycerol|Receptors, Lysophospholipid|*Lysophospholipids|G-Protein-Coupled Receptors|*Molecular Conformation|HEK293 Cells 26 GPR179 27471951 Vis. Neurosci. 2016 PMC6815669 10.1017/S0952523816000055 11 0 0 5 Mice|Humans|Animals|HEK293 Cells|Retinal Bipolar Cells|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|CACNA1S protein, human|*Voltage-Dependent Calcium Channels|Night Blindness|Retina|Electroretinography|Signal Transduction|*Isoforms|Western Blotting|*Antibodies|Mice, Knockout|Dendrites|GPR179 protein, mouse|Receptors, G-Protein-Coupled 25 GPR179 27428514 Ophthalmic Genet. 2016 10.1080/13816810.2016.1193876 0 0 0 5 Humans|Night blindness, congenital stationary|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|*Mutation|Electroretinography|Pedigree|Phenotype|Genotype|Retinal Diseases|Retina|Visual Acuity|*Chinese|CABP4 protein, human|Calcium-Binding Proteins 25 GPR179 26961947 J. Neurosci. 2016 PMC4783495 10.1523/JNEUROSCI.3833-15.2016 7 0 0 5 Mice|Animals|*RGS Proteins|*Retina|Retinal Bipolar Cells|metabotropic glutamate receptor 6|Receptor, Metabotropic Glutamate|Signal Transduction|GTP-Binding Protein beta Subunits|Membrane Proteins|Light 25 GPR179 26895961 J. Biol. Chem. 2016 PMC4861480 10.1074/jbc.M115.694075 3 0 0 5 Animals|Mice|RGS7 protein, human|*RGS Proteins|GTP-Binding Protein beta Subunits|Neurons|Carrier Proteins|Signal Transduction|Intracellular Signaling Peptides and Proteins|Mice, Knockout|Co-Immunoprecipitation|Transfections|Plasma Membrane|Brain|Rgs6 protein, mouse|Rgs7 protein, mouse 25 GPR26 27697106 BMB Rep 2016 PMC5346323 10.5483/bmbrep.2016.49.11.133 3 23 0 71 Humans|*Cell Migration|RHOA protein, human|rhoA GTP-Binding Protein|*Lung Cancer|GPRC5C protein, human|Receptors, G-Protein-Coupled|rac1 GTP-Binding Protein|A549 Cells|Cell Line, Tumor|Fibers, Stress|*Neoplastic Processes|Actin 20 GPR26 26740622 J. Biol. Chem. 2016 PMC4813461 10.1074/jbc.M115.695940 18 7 2 71 Humans|*rho GTPases|*Podosomes|RHOA protein, human|rhoA GTP-Binding Protein|*Signal Transduction|cdc42 GTP-Binding Protein|lysophosphatidic acid|Lysophospholipids|rac1 GTP-Binding Protein|rho-Associated Kinases|LPA1 Receptor|Pseudopodia|Actin 20 gpr34 27538994 J. Neurovirol. 2016 PMC5593752 10.1007/s13365-016-0472-1 8 2 0 33 Humans|*Microglia|*HIV-1|*HIV Infections|Monocyte|HIV Core Protein p24|Macrophage Colony-Stimulating Factor|AIDS Dementia Complex|Macrophages|Virus Replication|Granulocyte-Macrophage Colony-Stimulating Factor|Cells, Cultured 42 gpr34 27086875 Biochim. Biophys. Acta 2016 10.1016/j.bbamcr.2016.04.010 2 0 0 33 Humans|*Protein Transport|*Cell Membrane|Golgi Apparatus|Endoplasmic Reticulum|Amino Acid Sequence|Protein Structure, Tertiary|Signal Sequence|Amino Acid Motifs|G-Protein-Coupled Receptors|*Cell Movement|Mutagenesis, Site-Directed|Mutations|Transfection|TYRP1 protein, human|Membrane Glycoproteins|Microscopy, Fluorescence|Cell Line 42 gpr34 27077565 J. Med. Chem. 2016 10.1021/acs.jmedchem.5b01925 2 0 0 33 Humans|lysophosphatidylserine|*Glycerol|Receptors, Lysophospholipid|*Lysophospholipids|G-Protein-Coupled Receptors|*Molecular Conformation|HEK293 Cells 42 gpr34 26851221 J. Immunol. 2016 10.4049/jimmunol.1501326 3 0 0 33 Animals|Mice|*Mitogens|G-protein-coupled receptor 34|*Receptors, Lysophospholipid|*Cell Proliferation|*Apoptosis|*B Cells|Dendritic Cells|Flow Cytometry|Blotting, Western 42 GPR64 27760455 J. Bone Miner. Res. 2016 PMC7211037 10.1002/jbmr.3023 6 3 0 39 Humans|*Parathyroid Neoplasms|*Receptors, Calcium-Sensing|Hyperparathyroidism, Primary|GPRC5C protein, human|*Receptors, G-Protein-Coupled|Parathyroid Glands|*Signal Transduction|Parathyroid Hormone|Adenoma|CCND1 protein, human|Cyclin D1|Immunohistochemistry|Proteolysis|GPR64 protein, human 28 GPR64 27269053 Int J Hyperthermia 2016 10.1080/02656736.2016.1186290 6 3 0 39 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Septins|*Liver Neoplasms|Hyperthermia, Induced|*Apoptosis|*Up-Regulation|Cell Proliferation|Hep G2 Cells|*Genes, Tumor Suppressor|Cell Line, Tumor|Antineoplastic Agents|Xenograft Model Antitumor Assays|Mice, Nude|*Transcriptional Activation 28 GPR85 27184081 Genes Cells 2016 10.1111/gtc.12378 5 0 0 29 Humans|*Molecular Docking Simulation|Ligands|GPRC5C protein, human|G-Protein-Coupled Receptors|Small Molecule Libraries|*Brain|*Gene Expression|Molecular Model 25 GRID1 27306141 Eur. J. Neurosci. 2016 PMC5113795 10.1111/ejn.13300 3 2 1 73 Humans|Occipital Lobe|Alpha Rhythm|Magnetoencephalography|Parietal Lobe|Electroencephalography|Brain Mapping 36 GRIN3B 27542340 Neurosci. Lett. 2016 10.1016/j.neulet.2016.08.025 1 1 0 31 Male|Humans|*Heroin Dependence|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Frequencies, Allele|Haplotype|Genetic Predisposition to Disease|Genotype|*Receptors, N-Methyl-D-Aspartate|Linkage Disequilibrium|Allele|Case-Control Studies 21 GULP1 27288666 Nanomedicine 2016 10.1016/j.nano.2016.05.019 2 0 0 148 Humans|Male|Mice|Animals|liposomal doxorubicin|*Doxorubicin|*Polyethylene Glycols|Liposomes|Nanoparticles|*Strain, Inbred Mouse|Mononuclear Phagocyte System 37 H6PD 27866910 Cell Chem Biol 2016 PMC5182133 10.1016/j.chembiol.2016.10.011 23 15 0 587 *Poly(ADP-ribose) Polymerase Inhibitors|*Proteome|olaparib|Phthalazines|PARP2 protein, human|Poly ADP Ribose Polymerase|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Piperazines|niraparib|Indazoles|veliparib|Benzimidazoles|Piperidines|Antineoplastic Agents|Cell Line, Tumor|Apoptosis 65 H6PD 27208490 Brain Res. 2016 PMC4920069 10.1016/j.brainres.2016.05.030 2 13 0 587 Male|Rats|Animals|*Corticosterone|*Amphetamine-Related Disorders|*Hippocampus|Amfetamine|*Substance Withdrawal Syndrome|Central Nervous System Stimulants|Glucocorticoid|Serotonin|Glucocorticoid Receptor|11-beta-Hydroxysteroid Dehydrogenase Type 1|Restraint, Physical|Microdialysis|Anxiety 65 HEG1 27839947 Structure 2016 PMC5143164 10.1016/j.str.2016.10.001 5 44 0 40 rap1 GTP-Binding Proteins|*GTP-Binding Proteins|ras Proteins|Protein Binding|*Recognition, Psychology|Guanosine Triphosphate 37 HEG1 26780829 Elife 2016 PMC4733052 10.7554/eLife.11394 11 4 1 40 Proteomics|*Cell Junctions|rap1 GTP-Binding Proteins|Carrier Proteins|Protein Binding|Binding Site|Endothelial Cells|Signal Transduction|*Heart|Protein Domains 37 HELB 27402722 Health Promot Pract 2016 10.1177/1524839916658025 8 0 0 55 Humans|*Counseling|Residency|Family Practice|Internal Medicine|Gynecology|*Physical Activity|*Obesity|Obstetrics|Curriculum|Primary Care|*Nutritional Status|Surveys and Questionnaires|Overweight|Ohio 80 HELB 27079536 Sci Rep 2016 PMC4832242 10.1038/srep24510 2 4 1 55 Humans|*Resveratrol|*5' Flanking Region|Transcription Start Site|Promoter Regions, Genetic|Binding Sites|Reporter Gene|Luciferase|Chromatin Immunoprecipitation|Transcriptional Activation|Sp1 Transcription Factor|Transcription, Genetic|Base Sequence|DNA-Binding Proteins|Transfection|Electrophoretic Mobility Shift Assay|Protein Binding|HeLa Cells|DNA Helicases 80 HES2 27570480 Int. J. Biol. Sci. 2016 PMC4997050 10.7150/ijbs.16430 5 48 1 67 Animals|Rats|*Amyloid Precursor Protein Secretases|NOTCH3 protein, human|*Receptor, Notch3|*Ductus Arteriosus|*Ductus Arteriosus, Patent|*Rats, Wistar|*Smooth Muscle Cells|Muscle, Smooth, Vascular|Signal Transduction|Receptors, Notch|Angiotensin II|Cell Movement|Cell Proliferation|Vascular Remodeling|Downregulation|Reactive Oxygen Species|Basic Helix-Loop-Helix Transcription Factors|Cells, Cultured 55 HES2 27430888 Sci China Life Sci 2016 10.1007/s11427-016-5094-6 1 1 0 67 Humans|*Ryanodine Receptor Calcium Release Channel|*Myocytes, Cardiac|*Human Embryonic Stem Cells|*Aequorin|ITPR1 protein, human|Inositol 1,4,5-Trisphosphate Receptors|Calcium Signaling|Ryanodine|Sarcoplasmic Reticulum|*Cell Differentiation|Inositol 1,4,5-Trisphosphate|Calcium|Cells, Cultured 55 HINT2 26767982 Am. J. Physiol. Gastrointest. Liver Physiol. 2016 10.1152/ajpgi.00178.2015 1 0 0 69 Mice|Animals|*Protein, Mitochondrial|*Histidine|*Fatty Liver|Liver|Diet, High-Fat|Mitochondria, Liver|Triglycerides|Mitochondria|Fasting|Brown Fat|Mice, Knockout|Sirtuin 3|Uncoupling Protein 1|Malonyl CoA 32 HIVEP2 27028761 Cell Rep 2016 10.1016/j.celrep.2016.02.067 9 2 0 69 Mice|Animals|Retrospective Studies|Major Affective Disorder 2|Bipolar Disorder|*Disease Models, Animal|Hippocampus|Dentate Gyrus|CaM KII|Cyclic AMP Response Element-Binding Protein|Circadian Rhythm|Genetic Diseases, X-Linked 77 HIVEP2 27003583 Neurogenetics 2016 PMC4907844 10.1007/s10048-016-0479-z 10 5 1 69 Child|Humans|*Intellectual Disability|*Mutations|Developmental Disabilities|Sequencing, Whole Exome|Transcription Factor|Exome|*Musculoskeletal Abnormalities|HIVEP2 protein, human|DNA-Binding Proteins 77 HMCN1 27007659 PLoS ONE 2016 PMC4805164 10.1371/journal.pone.0152047 11 0 1 37 Humans|Aged|*Whole Exome Sequencing|Basal Laminar Drusen|*Retinal Drusen|*Age Related Macular Degeneration|*Bruch Membrane|*Eye Diseases, Hereditary|Complement Factor H|Heterozygote|Pedigree|Polymorphism, Single Nucleotide|Age-at-Onset|EFEMP1 protein, human|Extracellular Matrix Proteins|FBLN5 protein, human 47 HMGN3 27664238 Genes Dev. 2016 PMC5066241 10.1101/gad.285239.116 18 1 0 72 Humans|*Human Embryonic Stem Cells|Eukaryotic Initiation Factor-4G|Ribosomes|*Cell Differentiation|Protein Biosynthesis|Polysome|Apoptosis|mRNA 28 HMX1 27392729 Dev. Genes Evol. 2016 PMC6234122 10.1007/s00427-016-0555-2 1 0 0 76 Animals|Mice|*Xenopus laevis|*Genes, Homeobox|Phylogeny|Chicken|Xenopus Proteins|Transcription Factors|Homeodomain Proteins|*Ganglia|Amino Acid Sequence|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Sequence Alignment|In Situ Hybridization|Sequence Homology, Amino Acid|Medaka|*Head|SOHo protein, Xenopus 47 HMX1 27287804 Development 2016 PMC4958336 10.1242/dev.133736 2 1 0 76 Humans|Rats|Animals|Female|Cattle|Transcription Factor|Homeodomain Proteins|*Morphogenesis|*Ear Auricle|Enhancer Elements, Genetic|Gene Expression Regulation, Developmental|*External Ear|*Face|Base Sequence|Mesenchyme|*Biological Evolution 47 HMX2 27274859 Hum Genome Var 2016 PMC4871931 10.1038/hgv.2016.8 3 0 1 20 Humans|Microcephaly|Genes, Homeobox|Chromosome Deletion|Intellectual Disability|Phenotype|Urogenital Abnormalities|Gene Expression Regulation, Developmental|Hearing Loss, Sensorineural|*Chromosome Structures|Ear, Inner 40 HOOK3 27974047 J Transl Med 2016 PMC5157084 10.1186/s12967-016-1075-6 0 8 0 276 Adult|Humans|Child|*Gastrointestinal Stromal Tumors|Receptor, Platelet-Derived Growth Factor alpha|Proto-Oncogene Proteins c-kit|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|Succinate Dehydrogenase|Mutations 33 HOOK3 27482052 J. Cell Biol. 2016 PMC4970328 10.1083/jcb.201604002 47 5 1 276 Animals|*Dynactin Complex|*Dyneins|Cytoplasmic Dyneins|Microtubules|Microtubule-Associated Proteins|*Adaptor Proteins, Signal Transducing|*Carrier Proteins|Cell Movement 33 HOOK3 27365401 J. Biol. Chem. 2016 PMC5000072 10.1074/jbc.M116.738211 37 8 0 276 Animals|*Dynactin Complex|*Dyneins|Microtubules|Microtubule-Associated Proteins|Cytoplasmic Dyneins|Kinesin|*Cell Movement|Binding Proteins|Protein Binding|Protein Transport|Adaptor Proteins, Signal Transducing 33 HOXA6 26870170 Oncol Lett 2016 PMC4727036 10.3892/ol.2015.3893 3 2 0 56 Glioblastoma|Neoplasm Invasiveness|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Homeodomain Proteins|Transfection 36 hoxc11 27977683 PLoS Genet. 2016 PMC5157951 10.1371/journal.pgen.1006232 35 1 0 92 Mice|Animals|lncRNA|Hox Genes|Homeodomain Proteins|Polycomb-Group Proteins|Gene Expression Regulation, Neoplastic|Transcription Factors|Gene Expression Profiling|Phenotype|Hoxc12 protein, mouse 57 hoxc11 27080371 IUBMB Life 2016 10.1002/iub.1504 2 4 0 92 Mice|Animals|CTCF protein, human|CCCTC-Binding Factor|Hox Genes|Chromatin|Homeodomain Proteins|Epigenesis, Genetic|Repressor Proteins|DNA Methylation|Transcription Factors|Gene Expression Regulation|AKT1 protein, human|Proto-Oncogene Proteins c-akt|*Gene Expression 57 hoxc11 26857655 Mol. Biol. Rep. 2016 10.1007/s11033-016-3946-6 2 0 0 92 Humans|*DNA Methylation|MAML1 protein, human|HTATIP2 protein, human|*Transcription Factors|CpG Islands|*Gene Expression|Homeodomain Proteins|Oligonucleotide Array Sequence Analysis|Genes, Homeobox|Acetyltransferases|SOXC Transcription Factors|*Kidney 57 hoxc11 26768750 BMC Genomics 2016 PMC4712606 10.1186/s12864-016-2370-6 10 1 1 92 Humans|DNA Copy Number Variations|*Polymorphism, Single Nucleotide|*Hemangioblastoma|Loss of Heterozygosity|Comparative Genomic Hybridization|Oligonucleotide Array Sequence Analysis|Chromosome Aberrations|*Genomics|Genome, Human|*Polymerase Chain Reaction 57 hoxc11 26729820 J. Med. Genet. 2016 PMC4955942 10.1136/jmedgenet-2015-103505 7 1 0 92 Humans|Mice|Animals|*Clubfoot|*Flatfoot|Homeodomain Proteins|Genetic Predisposition to Disease|Lower Extremity 57 HSPB3 28018906 Front Mol Biosci 2016 PMC5155517 10.3389/fmolb.2016.00081 4 7 0 1045 Hereditary Sensory and Motor Neuropathy|Charcot-Marie-Tooth Disease|Heat-Shock Proteins|HSP27 Heat-Shock Proteins|Mutation|Protein-Serine-Threonine Kinases 48 HSPB3 27909051 J. Biol. Chem. 2016 PMC5241741 10.1074/jbc.M116.760413 35 5 0 1045 Humans|*Heat-Shock Proteins, Small|HEK293 Cells|CRYAB protein, human|alpha-Crystallin B Chain|HSPB1 protein, human|HSP27 Heat-Shock Proteins|*Protein Folding|Protein Multimerization|Amino Acid Sequence|Heat-Shock Proteins 48 HSPB3 27567740 Exp. 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Toxicol. 2016 10.1111/bcpt.12719 1 0 0 128 Animals|Rats|Muscle, Smooth, Vascular|Vasodilator Agents|Myocytes, Smooth Muscle|Vasodilation|Phenylephrine|Rats, Wistar|Aorta|Positron-Emission Tomography|Risk Assessment 106 ICA1 27765528 Math Biosci 2016 PMC5392448 10.1016/j.mbs.2016.10.002 0 4 0 128 Animals|Mice|*Mice, Inbred NOD|APECED protein|*Transcription Factor|ICA1 protein, human|*Autoantigens|Autoimmunity|Central Tolerance|Gene Expression Regulation|Diabetes Mellitus, Type 1|Immune Tolerance|T Cells|Epithelial Cells|mRNA|*Mathematical Models 106 IFRD1 27856249 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.11.063 0 3 0 110 Humans|Mice|Animals|BMP2 protein, human|*Bone Morphogenetic Protein 2|*Interferon|Osteoblasts|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteogenesis|Cell Differentiation|Bone|Transcription Factors|Signal Transduction|*Antiviral Agents|Homeostasis|Cell Line|IFRD1 protein, human|Immediate-Early Proteins|Ifrd1 protein, mouse|Membrane Proteins 74 IFRD1 27842724 Allergol Immunopathol (Madr) 2016 10.1016/j.aller.2016.08.007 1 2 0 110 Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Computational Biology|Transcription Factors|*Asthma|Signal Transduction 74 IFRD1 27782840 BMC Biol. 2016 PMC5080701 10.1186/s12915-016-0318-6 2 40 1 110 Myogenesis|*Cell Differentiation|MyoD Protein|Myoblasts, Skeletal|Myogenic Regulatory Factors|Immediate-Early Proteins|Muscle, Skeletal|Cells, Cultured|Membrane Proteins 74 IFRD1 27381458 Mol. Cell. Biol. 2016 PMC5021375 10.1128/MCB.01075-15 6 3 0 110 Mice|Animals|*Osteoclasts|TNFSF11 protein, human|RANK Ligand|Osteoclastogenesis|Bone Resorption|NFATC Transcription Factors|Osteoblasts|Cell Differentiation|NF-kappa B|Macrophages|Macrophage Colony-Stimulating Factor|Activator Protein-1|Bone Marrow Cells|Signal Transduction|*Hematopoiesis|Bone|Ifrd1 protein, mouse|Membrane Proteins 74 IFRD1 27358163 Mol. Reprod. Dev. 2016 10.1002/mrd.22673 0 2 0 110 Humans|Animals|Female|Horses|Rats|*Ovary|*Interferon|Theca Cells|Granulosa Cells|Ovulation|Chorionic Gonadotropin|Lutea, Corpora|Gonadotropins, Equine|*Cell Differentiation|Oogenesis|Oocyte|mRNA|In Situ Hybridization|Progesterone|*Antiviral Agents|Rats, Sprague-Dawley|Epidermal Growth Factor|Cell Cycle 74 IFRD1 27050729 Cell. Physiol. Biochem. 2016 10.1159/000443094 0 0 0 110 Mice|Animals|*Mice, Transgenic|*Proline|*Intestines|Intestine, Small|Immediate-Early Proteins|Short Bowel Syndrome|Membrane Proteins|Enterocytes|Triglycerides|Amino Acids 74 IGLL5 27362861 PLoS ONE 2016 PMC4928959 10.1371/journal.pone.0158001 6 4 1 24 Humans|*Retinal Vein Occlusion|*Vitreous Body|*Proteomics|Macular Edema|Vascular Endothelial Growth Factor A|*Body Fluids 21 IGSF11 27030267 J. Virol. 2016 PMC4886794 10.1128/JVI.00315-16 5 2 0 18 Humans|adenovirus receptor|*Glycosylation|*Coxsackievirus Infection|poliovirus receptor|*Receptors, Virus|coxsackievirus B receptor|Coxsackie B Viruses|*Enterovirus|Coxsackie and Adenovirus Receptor-Like Membrane Protein|Virus Binding|HeLa Cells 27 IGSF3 27328461 Dev Neurobiol 2016 10.1002/dneu.22412 3 0 0 44 *Neurons|*Morphogenesis|*Immunoglobulin|Neurogenesis|Cerebellum|Cell Differentiation|Membrane Protein|Gene Expression Regulation, Developmental|Signal Transduction|Cells, Cultured|Cell Proliferation 20 ILDR1 27764096 PLoS Genet. 2016 PMC5072625 10.1371/journal.pgen.1006371 18 1 1 64 Humans|Adult|*Genome-Wide Association Study|*Electronic Health Records|*Presbycusis|SNPs|Genetic Predisposition to Disease|Phenotypes|Genotype|Case-Control Studies|Cohort Studies|Whites|Ethnic Groups|EYA4 protein, human|Trans-Activators|ILDR1 protein, human|Receptors, Cell Surface 35 ILDR1 27260575 Int. J. Pediatr. Otorhinolaryngol. 2016 10.1016/j.ijporl.2016.04.005 6 0 0 64 Humans|Czech Republic|*Hearing Loss, Sensorineural|*Mutations|*Deafness|Homozygote|Connexins|Pedigree 35 ILDR1 27195292 Biomed Res Int 2016 PMC4852330 10.1155/2016/6137541 5 0 1 64 Humans|Animals|Mice|*Tight Junctions|Epithelial Cell|*Ear, Inner|Tricellulin|Hearing|Claudins|Mutations|ILDR1 protein, human|Receptors, Cell Surface|Ildr1 protein, mouse 35 immp2l 27932244 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.12.024 1 0 0 32 Humans|*Astrocytes|*Mitochondria|Mitochondrial Membranes|*Endopeptidases|Mitochondrial Proteins|Tourettes Syndrome|Exons|Mutation|Brain|IMMP2L protein, human 57 immp2l 27920664 Front Neurosci 2016 PMC5118467 10.3389/fnins.2016.00531 2 0 0 32 Tourette Syndrome|Genetic Predisposition to Disease|Haplotypes|Polymorphism, Single Nucleotide|Genotype|Nerve Tissue Proteins|Vocal Tics 57 IMPG1 26849151 Ophthalmic Genet. 2016 10.3109/13816810.2015.1059456 0 0 0 26 Adult|Humans|*Vitelliform Macular Dystrophy|*Polymorphism, Single Nucleotide|Bestrophins|Fluorescein Angiography|Peripherins|Phenotype|Eye Proteins|Tomography, Optical Coherence|Mutations|Visual Acuity 29 INSL4 27933606 Br. J. Pharmacol. 2016 PMC5406299 10.1111/bph.13689 7 0 0 17 Male|Female|Humans|Animals|Mice|*Relaxin|peptide B|Insulin|*Genitalia, Male|Leydig Cells|Prostate|relaxin-3 protein, mouse|Insl6 protein, mouse|Intracellular Signaling Peptides and Proteins 45 insl6 27933606 Br. J. Pharmacol. 2016 PMC5406299 10.1111/bph.13689 7 0 0 28 Male|Female|Humans|Animals|Mice|*Relaxin|peptide B|Insulin|*Genitalia, Male|Leydig Cells|Prostate|relaxin-3 protein, mouse|Insl6 protein, mouse|Intracellular Signaling Peptides and Proteins 40 insl6 27865410 Theriogenology 2016 10.1016/j.theriogenology.2016.09.047 7 1 0 28 Humans|Male|*Testis|*Transcriptome|*Infertility, Male|Arrest of spermatogenesis|Azoospermia|Spermatogonia|Spermatogenesis|Sperm|Spermatocytes|Transcriptome Profiling|Meiosis|TSSK2 protein, human|Protein-Serine-Threonine Kinases|NLRP14 protein, human|Nucleoside-Triphosphatase|RNF212 protein, human|Ligases 40 insl6 27808243 Sci Rep 2016 PMC5093412 10.1038/srep36354 4 0 0 28 Humans|Male|Swine|Animals|Glycogen Synthase Kinase 3|Breeding|*Genomics|Selection, Genetic|Sus scrofa|Chromosome Mapping|Domestication|Genotype|Quantitative Trait Loci|Sequence Analysis, DNA|Phenotypes|Polymorphism, Single Nucleotide|*Chinese|China 40 insl6 26846852 J. Biol. Chem. 2016 PMC4807277 10.1074/jbc.M115.699660 7 0 0 28 Humans|Male|Mice|Animals|*Spermatogenesis|Cullin Proteins|E3 Ligase|Ubiquitination|Infertility, Male|Spermatozoa|Sperm Motility|*B-Lymphocytes|DNA-Binding Proteins|CUL4A protein, human|CUL4B protein, human|Cul4B protein, mouse|Insl6 protein, mouse|Intracellular Signaling Peptides and Proteins 40 INSRR 27052924 Nutr Metab Cardiovasc Dis 2016 10.1016/j.numecd.2016.01.010 1 5 0 284 Rats|Animals|*Myocytes, Cardiac|*Very-Low-Density Lipoproteins|*Biological Transport|Insulin|AMP-Activated Kinase|Phosphorylation|Free Fatty Acids|Signal Transduction|Oligomycin|Glucose|Hypoglycemic Agents|Deoxyglucose|Protein-Serine-Threonine Kinases|Myocardium|Oxidation-Reduction|Lipoproteins, LDL 86 INSRR 26929985 Epigenetics 2016 PMC4854556 10.1080/15592294.2016.1154246 11 0 0 284 *Urinary Bladder Neoplasms|Neoplasm Recurrence, Local|DNA Methylation|Carcinoma, Transitional Cell|PRRX1 protein, human|Homeodomain Proteins|Promoter Regions, Genetic|Prognosis|CpG Islands|STAT5A protein, human|Tumor Suppressor Proteins|Biomarkers, Tumor|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Bladder|Disease Progression|STAT5 Transcription Factor 86 IPO7 27381982 Int. J. Biochem. Cell Biol. 2016 10.1016/j.biocel.2016.06.024 3 32 0 322 AKT1 protein, human|*Proto-Oncogene Proteins c-akt|Phosphorylation|Tyrosine Kinase, SYK|Receptors, Antigen, B-Cell|Intracellular Signaling Proteins|Signal Transduction|Protein-Tyrosine Kinases|Adaptor Proteins, Signal Transducing|14-3-3 Proteins|Downregulation|Cell Line|Karyopherins 55 IPO7 26971296 Clin Neurol Neurosurg 2016 10.1016/j.clineuro.2016.02.041 7 0 0 322 Child|Humans|Familial ependymoma|*Ependymomas|*Genomics|DNA Methylation|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Brain Neoplasms|Gene Expression|Chromosome Aberrations 55 IRGC 27185123 Carbohydr Polym 2016 10.1016/j.carbpol.2016.04.057 0 0 0 17 *Amylopectin|*Oryza|alpha-Amylases|Dextrins|Hydrolysis|*Food Hypersensitivity 32 IRGC 27086357 J. Assist. Reprod. Genet. 2016 PMC4889487 10.1007/s10815-016-0715-3 11 0 0 17 Humans|Male|Infertility, Male|Spermatozoa|Homozygote|Vesicular Transport Proteins|Point Mutation|Membrane Proteins|Gene Deletion|Mutation|Homeodomain Proteins|SPATA16 protein, human 32 IRGC 26893422 Genome Announc 2016 PMC4759069 10.1128/genomeA.01703-15 0 0 1 17 Humans|*Oryza|*Genome, Chloroplast|Genome, Plant|Genes, Plant|Genetic Variation|Phylogeny|Chloroplast|Crops, Agricultural|*Asian|Indonesia 32 IRX4 27783221 Brain Struct Funct 2016 10.1007/s00429-016-1326-6 3 0 0 60 Animals|Transcription Factors|*Chickens|Homeodomain Proteins|Ear, Inner|Gene Expression Regulation, Developmental|Embryonic Development|Vertebrate|Epithelium|Cell Differentiation 63 IRX4 27570947 Stem Cells 2016 PMC5123941 10.1002/stem.2486 5 0 0 60 Mice|Animals|*Multipotent Stem Cells|*Heart Ventricles|Myocardium|Cell Differentiation|Myocytes, Cardiac|LIM-Homeodomain Proteins|Embryonic Stem Cells|Homeodomain Proteins|Cell Lineage|Organogenesis|Cell Line|Transcription Factors|Cells, Cultured|Gene Expression Regulation, Developmental|Myocytes, Smooth Muscle|Endothelial Cells|Irx4 protein, mouse 63 IRX4 27498391 J Proteomics 2016 10.1016/j.jprot.2016.07.030 0 0 0 60 Humans|Female|*Proteomics|Cancer Biomarkers|Proteome|Prognosis|Gene Expression Regulation, Neoplastic|*Plasma 63 IRX4 27496188 Medicina (Kaunas) 2016 10.1016/j.medici.2016.04.001 1 0 0 60 Macular dystrophy, retinal, 1, North Carolina type|DNA Copy Number Variations|Macular Dystrophy, Retinal, 2|*Corneal Dystrophies, Hereditary|*Genetic Linkage|Fluorescein Angiography|Pedigree|Retina|Tomography, Optical Coherence|Macular Dystrophy|Eye Proteins|Phenotype|Retinal Dystrophies|Transcription Factors 63 IRX4 27172222 G3 (Bethesda) 2016 PMC4889666 10.1534/g3.116.029975 5 0 1 60 Animals|Mice|*Scoliosis|*Kyphosis|Allele|Genetic Linkage|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Homeodomain Proteins|Chromosome Mapping|Transcription Factors|Zebrafish|Regulatory Sequences, Nucleic Acid|Genetic Heterogeneity|Base Sequence|*Chromosome Structures|Irx4 protein, mouse 63 ISL2 26892722 Andrologia 2016 10.1111/and.12545 0 2 0 74 Mice|Male|Animals|*Animals, Newborn|*Testis|Neurodegenerative Diseases|Hedgehog Proteins|*Motor Neuron|Embryonic Stem Cells|Cell Differentiation|NES protein, human|Nestin|OLIG2 protein, human|Oligodendrocyte Transcription Factor 2|Cells, Cultured|Retinoic Acid 55 ISM1 27942099 Niger Med J 2016 PMC5126744 10.4103/0300-1652.193857 3 0 0 121 Humans|Male|*Pentoxifylline|*Asthenozoospermia|*Spermatozoa|*Infertility, Male|Sperm Motility|Semen|methylxanthine|Xanthines 26 ITIH5 27613302 Pathologe 2016 10.1007/s00292-016-0207-3 0 1 0 60 *Urinary Bladder Neoplasms|*Tumorigenesis|Epigenesis, Genetic|DNA Methylation|Urothelium|Preinvasive Carcinoma|*Cell Transformation, Neoplastic|Gene Silencing|Urinary Bladder|*Epigenetics|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Downregulation|*Regulatory Genes|DNA Mutational Analysis 37 ITIH5 27143355 J. Biol. Chem. 2016 PMC4919461 10.1074/jbc.M115.670521 8 12 0 60 *Myofibroblasts|*Fibroblast Growth Factor 1|CD44 protein, human|Hyaluronan Receptors|*Cell Differentiation|alpha-1-microglobulin|Alpha-Globulins|Hyaluronan|Fibroblasts|Transforming Growth Factor beta1|Cell Adhesion Molecules|Cell Line|EGFR protein, human|Epidermal Growth Factor Receptor|Wound Healing|*Tumor|Tumor Necrosis Factors 37 ITIH5 26971296 Clin Neurol Neurosurg 2016 10.1016/j.clineuro.2016.02.041 7 0 0 60 Child|Humans|Familial ependymoma|*Ependymomas|*Genomics|DNA Methylation|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Brain Neoplasms|Gene Expression|Chromosome Aberrations 37 ITM2A 27809695 J. Clin. Endocrinol. Metab. 2016 10.1210/jc.2016-2625 2 1 0 90 Humans|*Graves Disease|Genetic Predisposition|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genetic Association Studies|Asian Continental Ancestry Group|Gene Frequency|Alleles|Genotype|Case-Control Studies|Autoimmune Disease|ITM2A protein, human|Membrane Proteins 47 ITM2C 27456605 Sci Rep 2016 PMC4960555 10.1038/srep28836 2 15 1 80 Female|Animals|*Egg Shell|*Genome-Wide Association Study|Chickens|*Eggs|*Phenotype|SNPs|Haplotypes|Poultry|Chromosome 27 KCNT2 27682982 J. Physiol. (Lond.) 2016 PMC5374106 10.1113/JP273225 3 0 0 55 Animals|Ion Channel Gating|Potassium Channels|Membrane Potentials|Patch-Clamp Techniques|Xenopus laevis|Sodium|Structure-Activity Relationship|Oocytes 56 KCNT2 27091544 J. Neuroendocrinol. 2016 10.1111/jne.12394 5 0 0 55 Rats|Animals|Voltage-Clamp Techniques|*Neurons|Supraoptic Nucleus|*Sodium|Action Potentials|Membrane Potentials|Potassium Channels|Tetrodotoxin|AVP protein, human|Vasopressin|Lithium|Neurophysins 56 KCTD12 28003345 J. Neurosci. 2016 PMC6596860 10.1523/JNEUROSCI.2181-16.2016 8 3 0 183 Animals|Cricetinae|*GABA-B Receptor|*Hippocampus|*Kinetics|Cricetulus|Neurons|CHO Cells|Potassium 55 KCTD12 28000887 Oncol. Rep. 2016 10.3892/or.2016.5325 5 1 0 183 Mice|Animals|Humans|Uveal melanoma|Mice, Nude|Proteomics|*Uveal Neoplasms|*Melanoma|Cell Proliferation|Cell Cycle|Apoptosis|Cell Movement|Cell Line, Tumor|Western Blotting|Transfection|RNA, Messenger|KCTD12 protein, human|Proteins 55 KCTD12 27717812 Behav. Brain Res. 2016 10.1016/j.bbr.2016.10.006 2 0 0 183 Animals|Mice|*Endophenotypes|*gamma-Aminobutyric Acid|Receptors, GABA-B|Hippocampus|Neurons|Mice, Knockout|Brain 55 KIAA0196 27957547 Neurol Genet 2016 PMC5141523 10.1212/NXG.0000000000000122 10 0 0 71 Humans|*Spastic Paraplegia, Hereditary|DNA Mutational Analysis|Pedigree|Mutation|Membrane Proteins|Canada 35 KIAA0196 27390154 Pigment Cell Melanoma Res 2016 PMC5082549 10.1111/pcmr.12506 8 17 1 71 Mice|Animals|*Color|KIAA0196 protein, human|Actin|Actin-Related Protein 2-3 Complex|Microfilament Proteins|Actin Cytoskeleton|Protein Transport|Endosomes|Vesicular Transport Proteins|Hereditary Spastic Paraplegia|Cell Movement|*Melanocytes 35 KIAA0196 26967522 Clin Neurol Neurosurg 2016 10.1016/j.clineuro.2016.02.031 3 0 0 71 Humans|*Mutation, Missense|*Exome|Japan|Hereditary Spastic Paraplegia|*Whole Exome Sequencing|Pedigree|Mutations|Paraplegia|Proteins|KIAA0196 protein, human 35 KIAA0196 26965651 Nat Commun 2016 PMC4792963 10.1038/ncomms10961 30 27 1 71 Humans|Mice|Animals|Dogs|LDLR protein, human|*Low Density Lipoprotein Receptor|*Endosomes|Hypercholesterolemia|Cholesterol|Cholesterol, LDL|KIAA0196 protein, human|Protein Transport|Adaptor Proteins, Signal Transducing|Atherogenesis|Liver|Endocytosis|Mice, Knockout|CCDC22 protein, human|Proteins 35 KLF16 27796151 Thyroid 2016 PMC5314727 10.1089/thy.2016.0285 14 0 0 93 *Thyroid Carcinoma, Anaplastic|*Upregulation|Thyroid Cancer|Gene Expression Regulation, Neoplastic|*Cell Cycle|MicroRNAs|Down-Regulation|Gene Expression Profiling|*Transcriptional Activation|Biomarkers, Tumor|*B-Lymphocytes|Computational Biology|Signal Transduction|*M Phase 26 KLF16 27611969 PLoS ONE 2016 PMC5017575 10.1371/journal.pone.0162238 7 9 1 93 Mice|Animals|*Adipogenesis|*RNA-Seq|3T3-L1|CCAAT-Enhancer-Binding Protein-alpha|Cell Differentiation|PPAR gamma|CCAAT Enhancer Binding Protein|Adipocytes, Brown|Kruppel-Like Transcription Factors|Transcriptional Activation|Gene Expression|Klf16 protein, mouse 26 KLF16 27402841 J. Biol. Chem. 2016 PMC5000058 10.1074/jbc.M116.732339 6 3 0 93 *Retinal Ganglion Cells|*Ephrin A5|EPHA5 protein, human|*Receptor, EphA5|*Neurite Outgrowth|Kruppel-Like Transcription Factors|Retina|Transcription Factors|Gene Expression Regulation|Signal Transduction 26 KLK15 26848109 Bioorg. Med. Chem. Lett. 2016 10.1016/j.bmcl.2016.01.039 0 0 0 19 Humans|*Tissue Kallikreins|morelloflavone|KLK15 protein, human|*Kallikreins|*Biflavonoids|flavone|*Flavones|Serine Proteinase Inhibitors|Structure-Activity Relationship|Serine Proteases|Natural Products 53 KLLN 27663866 In Vitro Cell. Dev. Biol. Anim. 2016 10.1007/s11626-016-0093-2 10 1 0 121 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Cell Proliferation|*Upregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|Apoptosis|Signal Transduction|Cell Movement|Cell Line, Tumor|*Transcriptional Activation|RNA, Messenger|Cell Cycle Checkpoints|Cell Survival|MIRN224 microRNA, human 31 KLRC4 27467286 Genes Immun. 2016 10.1038/gene.2016.28 2 0 0 16 Male|Humans|Female|Leukocytes, Mononuclear|*Testosterone|*Behcet Disease|TLR4 protein, human|Toll-Like Receptor 4|Cytokines|Neutrophils|Interleukin 12|STAT4 Transcription Factor|*Testosterone Congeners|Gene Expression|IL10 protein, human|Interleukin-10|ERAP1 protein, human|Aminopeptidases|Minor Histocompatibility Antigens 24 KLRC4 26890122 PLoS ONE 2016 PMC4758705 10.1371/journal.pone.0149052 3 0 1 16 Humans|Genome-Wide Association Study|Behcet Syndrome|Genetic Predisposition to Disease|Gene Expression Profiling|Immunogenetic|Case-Control Studies|Bioinformatics|CD180 protein, human|Antigens, CD|ERAP1 protein, human|Aminopeptidases|Minor Histocompatibility Antigens|CLEC12A protein, human|Receptors, Mitogen|Lectins, C-Type 24 LACRT 27711909 Invest. Ophthalmol. Vis. Sci. 2016 PMC5063056 10.1167/iovs.16-19309 7 2 1 69 Humans|*Tear|*Cornea|Keratoconjunctivitis Sicca|Sjogren's Syndrome|Conjunctiva|*Lacerations 27 LACRT 27436115 Sci Rep 2016 PMC4951640 10.1038/srep29629 21 3 1 69 Humans|*Proteomics|*Tears|*Evaporative Dry Eye|Proteome|Chromatography, Liquid|Tandem Mass Spectrometry|Eye Proteins|DMBT1 protein, human|Receptors, Cell Surface|LACRT protein, human|Glycoproteins 27 LAD1 27756787 Clin. Cancer Res. 2016 10.1158/1078-0432.CCR-16-1236 9 0 0 596 84 LAD1 27472710 Medicine (Baltimore) 2016 PMC5265847 10.1097/MD.0000000000004321 10 10 1 596 Humans|*Triple-Negative Breast Cancer|Neoplasm Recurrence, Local|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|MicroRNAs|*Genetic Profile|Biomarkers, Tumor|Molecular Targeted Therapy|*Drug Delivery Systems|Genomics 84 laptm5 27922670 Int. J. Oncol. 2016 10.3892/ijo.2016.3788 3 9 0 113 Humans|*Urinary Bladder Neoplasms|*Down-Regulation|*Cell Proliferation|*Cell Cycle Arrest|*G0 Phase|LAPTM5 protein, human|*Membrane Protein|*Bladder|Apoptosis|Epithelial-Mesenchymal Transition|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Tumorigenesis|E3 Ubiquitin Ligase|Lysosome|G1 Phase 49 laptm5 27058622 Oncotarget 2016 PMC5053729 10.18632/oncotarget.8614 3 11 1 113 Humans|*Down-Regulation|Carcinoma, Non-Small-Cell Lung|Esophageal Neoplasms|Esophageal Squamous Cell Carcinoma|Lung Neoplasms|LAPTM5 protein, human|*Membrane Protein|Lysosomes|Gene Expression Regulation, Neoplastic|Ubiquitin-Protein Ligases|Cell Line, Tumor|Autophagy|Tumorigenesis|Cell Death 49 laptm5 26903547 Blood 2016 10.1182/blood-2015-11-680199 5 0 0 113 Humans|*Waldenstrom Macroglobulinemia|*Whole Exome Sequencing|*Exome|Genetic Predisposition|Alleles|Pedigree|Lymphoproliferative Disorders|B-Lymphocytes|Immunoglobulin M|Mutation|*Germ Line|*Databases, Genetic|LAPTM5 protein, human|Membrane Proteins 49 LARP6 27011170 Int J Mol Sci 2016 PMC4813270 10.3390/ijms17030419 7 29 1 495 Animals|*Collagen Type I|*mRNA|*Collagen|Ribonucleoproteins|RNA-Binding Proteins|5' Untranslated Region|Autoantigens|Protein Binding|Gene Expression Regulation|STRAP protein, mouse|Adaptor Proteins, Signal Transducing|Vimentin|Cells, Cultured|Intermediate Filaments|Fibrosis 35 LARP6 26982883 PLoS ONE 2016 PMC4794124 10.1371/journal.pone.0138014 9 6 1 495 Humans|*Coronary Artery Disease|Taiwan|SNPs|Genome-Wide Association Study|Genetic Predisposition to Disease|Linkage Disequilibrium|Asian Continental Ancestry Group|Allele|Genotype|Case-Control Studies|European Continental Ancestry Group|Risk Factors|Followup Studies|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1 35 LARP6 26932461 Sci Rep 2016 PMC4773855 10.1038/srep22597 12 36 1 495 Humans|*Collagen Type I|*Phosphorylation|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Ribonucleoproteins|RNA Binding Protein|mRNA|Autoantigens|Collagen|Protein Binding|Fibroblasts|Fibrosis 35 LBX2 26820155 PLoS Genet. 2016 PMC4731154 10.1371/journal.pgen.1005802 13 11 1 16 Humans|Animals|Adolescent|*Zebrafish|*Genes, Homeobox|*Scoliosis|Genome-Wide Association Study|Homeodomain Proteins|Gastrulation|Transcription Factors|Single Nucleotide Polymorphism|*Kyphosis|Morphogenesis 34 LGALS12 27256573 J. Leukoc. Biol. 2016 PMC6608023 10.1189/jlb.1HI0316-134R 2 1 0 461 Humans|*Leukemia, Promyelocytic, Acute|*Lipogenesis|Tretinoin|Cell Differentiation|HL-60 Cells|Hematopoiesis|*Leukopoiesis|Galectin 24 LGALS12 26873172 Glycobiology 2016 10.1093/glycob/cww013 3 6 0 461 Animals|*Insulin Resistance|*Macrophages|Macrophage Activation|*Adipocytes|*Inflammation|Lipopolysaccharides|STAT3 protein, human|STAT3 Transcription Factor|Cell Polarity|IL10 protein, human|IL10|Signal Transduction|Insulin|Cytokines|Galectins|Media, Conditioned|Nitric Oxide 24 LHX5 27932958 Front Neuroanat 2016 PMC5121248 10.3389/fnana.2016.00113 3 0 0 58 Animals|*Shark|*Hypothalamus|*Biological Evolution|Vertebrate|Homeodomain Proteins|Gene Expression Regulation, Developmental|Brain 61 LHX5 27769567 Biol. Psychiatry 2016 10.1016/j.biopsych.2016.08.010 27 0 0 58 Mice|Animals|Pregnancy|Female|*DNA Methylation|*B-DNA|*Neurodevelopmental Disorders|*Disease Models, Animal|Mice, Inbred C57BL|Prenatal Exposure Delayed Effects|Schizophrenia|Prefrontal Cortex|Poly I-C|gamma-Aminobutyric Acid|Infections 61 LHX5 27160258 Brain Struct Funct 2016 PMC5225162 10.1007/s00429-016-1229-6 6 2 1 58 Animals|Mice|*Genetic Profile|Chickens|*Amygdala|Transcription Factors|Homeodomain Proteins|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Neurons|Finches|Foxp2 protein, mouse|Repressor Proteins|Forkhead Transcription Factors|Lhx9 protein, mouse|LIM-Homeodomain Proteins 61 lignin 32665764 Green Chem 2016 PMC7359876 10.1039/c6gc02477g 0 0 0 0 *Carbon|titanium dioxide|*Titanium|Lignin|Hybrid-B|*Plasminogen Activators 17508 LIM2 27820671 J. Clin. Endocrinol. Metab. 2016 10.1210/jc.2016-3158 3 0 0 80 Humans|*Pituitary Gland|LIM-Homeodomain Proteins|Hypopituitarism|*Pituitary Diseases|*Mutations|Transcription Factor|Homeodomain Proteins|Heterozygote|*Cohort Studies|LHX4 protein, human 116 LIM2 27814360 PLoS ONE 2016 PMC5096708 10.1371/journal.pone.0162620 4 0 1 80 *Cataract|*Mutation|Genes, Recessive|Lens, Crystalline|Pedigree|Lod Score|Genetic Linkage|Eye Proteins|Mutation, Missense|Microsatellite Repeats 116 LIM2 27665712 Mol. Cell. Neurosci. 2016 10.1016/j.mcn.2016.09.001 1 0 0 80 Animals|*Neurogenesis|bcl-X Protein|Motor Neurons|Spinal Cord|Apoptosis|Gene Expression Regulation, Developmental|*Mammals 116 LIM2 27246950 Int J Comput Assist Radiol Surg 2016 PMC6524142 10.1007/s11548-016-1421-4 0 0 0 80 Swine|Animals|*Transcatheter Aortic Valve Replacement|*Robotic Surgical Procedures|Aortic Valve|Heart Valve Prosthesis|Bioprosthesis|Aortic Valve Stenosis|*Magnetic Resonance Imaging|Heart Valve Prosthesis Implantation|*Fluoroscopy|Surgery, Computer-Assisted|Prosthesis Design 116 LIM2 26769900 J. Cell. Sci. 2016 PMC4760372 10.1242/jcs.170571 6 3 1 80 Swine|Animals|Endothelial Cells|MMP14 protein, human|Membrane-Type 1 Matrix Metalloproteinase|Neovascularization, Physiologic|*Metalloproteases|Cell Motility|*Transcription Factors|Cells, Cultured|Neovascularization, Pathologic|Proteolysis 116 LIMA1 27104745 Cell Cycle 2016 PMC4845929 10.1080/15384101.2016.1146834 2 3 0 489 Humans|Animals|IQ motif containing GTPase activating protein 1|Drosophila melanogaster|*Cell Division|ras GTPase-Activating Proteins|Cytoskeletal Proteins|Myosin Light Chains|Cytokinesis|Actins|Carrier Proteins|Actin Cytoskeleton|Neoplasm Proteins|ARV1 protein, human|Membrane Proteins 43 LIMA1 27035883 Int. J. Oncol. 2016 10.3892/ijo.2016.3462 2 2 0 489 Humans|Female|*Carcinoma, Ovarian Epithelial|*Prognosis|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|*Disease Progression|Cell Proliferation|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Cytoskeletal Proteins|Cell Movement|Biomarkers, Tumor|mRNA|TYRP1 protein, human|*Membrane Glycoproteins|Immunohistochemistry|Cell Cycle|Kaplan-Meier Estimate 43 LIMA1 26981201 World J Biol Chem 2016 PMC4768116 10.4331/wjbc.v7.i1.128 1 9 0 489 *Proteolysis|*Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein|*Ubiquitination|TRAF2|Oncogene Proteins, Fusion|Signal Transduction|Tifab protein, human|TRAF6|*Oncogene Proteins|NF-kappa B|MALT Lymphoma|Chromosomal Translocation|Protein Binding|Ubiquitin-Protein Ligases|B-Lymphocytes|Apoptosis Regulatory Proteins|Cell Transformation, Neoplastic 43 LIMA1 26753958 Tumour Biol. 2016 10.1007/s13277-015-4767-2 6 0 0 489 *Pituitary Neoplasms|*Proteomics|*Computational Biology|*Transcriptome|Chromatography, Liquid|Tandem Mass Spectrometry|Adenoma|Biomarkers, Tumor|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Microarray Analysis|Western Blot|Real-Time Polymerase Chain Reaction|Signal Transduction 43 Lingo2 27445529 Can. Respir. J. 2016 PMC4904514 10.1155/2016/3564341 4 5 1 36 Humans|Adult|Female|Genome-Wide Association Study|Canada|*Asthma|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Genetic Predisposition to Disease|Genetic Association Studies|Allele|Chromosome Mapping|Genotype|Phenotypes|Lung|Case-Control Studies|Cohort Studies 31 LMTK2 27524905 Onco Targets Ther 2016 PMC4966688 10.2147/OTT.S104775 1 1 1 253 Humans|Male|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Prostate Cancer|Odds Ratio 47 LMTK2 27474411 Biochem. J. 2016 PMC5074368 10.1042/BCJ20160571 9 30 1 253 Humans|myosin VI|*Protein Binding|*Myosin Heavy Chains|Myosin|Actins|Adaptor Proteins, Signal Transducing|Binding Sites|Deafness|Adenosine Triphosphatases|Mutation|*Biophysical Phenomena|Actin Cytoskeleton|Pakistan 47 LPHN2 27807832 Methods Mol. Biol. 2016 10.1007/978-1-4939-6539-7_7 13 4 0 177 Humans|Male|*Cell Survival|*Proteome|*Transcriptome|*Biomarkers, Tumor|Apoptosis Regulatory Proteins|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Oncogenes|Cell Proliferation|Docetaxel|*Neoplastic Processes|RNA, Micro|NF kB|mRNA|TNFAIP8 protein, human 29 LPHN2 26868259 BMC Genet. 2016 PMC4751652 10.1186/s12863-016-0345-x 4 0 1 177 Orofacial Cleft 1|*Cleft Lip|*Cleft Palate|Malaysia|*Genetic Linkage|Pedigree|Lod Score|Chromosome Mapping|*Brain|Genetic Predisposition to Disease|Genotype|Microsatellite Repeats|*Families, Extended|Palate 29 LRIG3 27628597 Curr Cancer Drug Targets 2016 10.2174/156800961701161202200445 2 1 0 135 Humans|*Prognosis|Membrane Proteins|*Cancer|Membrane Glycoproteins|Upregulation|LRIG1 protein, human 50 LRIG3 27009049 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2016 10.1152/ajpregu.00309.2015 5 3 0 135 Humans|Female|Mice|Animals|*Cardiac Hypertrophy|Heart|Myocardium|Blood Pressure|Mice, Knockout|Mice, Inbred C57BL|Heart Rate|Heart Failure|Echocardiography|Hypertension|Organ Size|*Genes, Regulator|Disease Models, Animal|Lipoproteins, HDL|Cholesterol|LRIG3 protein, human|Membrane Proteins|Lrig3 protein, mouse 50 LRRC26 27238269 Int. Rev. Neurobiol. 2016 10.1016/bs.irn.2016.03.016 0 0 0 54 Animals|*Large-Conductance Calcium-Activated Potassium Channels|Hair Cells, Auditory, Inner|Hair Cells, Auditory|*Ear, Inner|Cochlea|Membrane Potentials|*Vertebrate|Calcium Channels 29 LRRC26 27115952 Ann Am Thorac Soc 2016 PMC5015721 10.1513/AnnalsATS.201507-405KV 7 0 0 54 Humans|*Potassium|Large-Conductance Calcium-Activated Potassium Channels|Mucociliary Clearance|Neoplasm Proteins|Voltage-Gated K+ Channels|*Respiratory System|Signal Transduction|LRRC26 protein, human 29 LRRC26 31265510 Mol. Pharmacol. 2016 PMC4702097 10.1124/mol.115.075234err 0 0 0 54 Large-Conductance Calcium-Activated Potassium Channels|Membrane Potentials|Neoplasm Proteins|Calcium 29 LRWD1 27924004 Nucleic Acids Res. 2016 PMC5389698 10.1093/nar/gkw1211 11 21 0 85 *Heterochromatin|Chromatin|Origin Recognition Complex|Histone|Replication Origins|DNA Replication|Histone-Lysine N-Methyltransferase|S Phase|Cell Nucleus|Cell Cycle|Protein Processing, Post-Translational|Protein Binding|Binding Sites|G1 Phase|DNA Methylation|Adaptor Proteins, Signal Transducing|Sequestosome-1 Protein 22 LRWD1 27760381 Gene 2016 10.1016/j.gene.2016.10.021 4 2 0 85 Humans|EWS-FLI fusion protein|*Sarcoma, Ewing|*RNA Interference|*Leucine|*Cell Survival|*WD40 Repeats|*RNA-Binding Protein EWS|*Proto-Oncogene Protein c-fli-1|*Oncogene Proteins, Fusion|*Neuroectodermal Tumors, Primitive, Peripheral|Bone Neoplasms|siRNA|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Genes, Regulator|Cell Proliferation|Signal Transduction|Apoptosis 22 LRWD1 26765314 Nucleus 2016 PMC4915504 10.1080/19491034.2015.1102814 5 6 0 85 Humans|*Histones|*Heterochromatin|*Transferases|Histone-Lysine Methyltransferase|Chromatin|Mark, Histone|DNA Replication|Lysine|Origin Recognition Complex|Gene Silencing|Protein Binding|LRWD1 protein, human|Microtubule Proteins 22 Ly75 27965521 Dis. Markers 2016 PMC5124651 10.1155/2016/6485343 3 1 0 198 Humans|Genome-Wide Association Study|Colitis, Ulcerative|Crohn's Disease|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Inflammatory Bowel Disease|Haplotypes|Genotype|Phenotype|Case-Control Studies|European Continental Ancestry Group 29 Ly75 27346686 Am. J. Hum. Genet. 2016 PMC5005441 10.1016/j.ajhg.2016.05.005 28 0 0 198 Humans|*Platelets|Mean Platelet Volume|Platelet Count|Thrombopoiesis|Hemostasis|Allele Frequency|Phenotype|MRVI1 protein, human|Phosphoproteins|Membrane Proteins|IQGAP2 protein, human|ras GTPase-Activating Proteins|PEAR1 protein, human|Receptors, Cell Surface 29 Ly75 27032500 Vet. Immunol. Immunopathol. 2016 10.1016/j.vetimm.2016.03.002 1 0 0 198 Animals|*Transcriptome|Phylogeny|Toll-Like Receptors|Receptors, Pattern Recognition|*Spleen|Gene Expression Profiling|Evolution, Molecular|Immunity, Innate|Genome|Signal Transduction|Genomics|*Lizards 29 Ly75 26871602 Oncotarget 2016 PMC4924702 10.18632/oncotarget.7288 8 7 1 198 Humans|Female|*Carcinoma, Ovarian Epithelial|mannose receptor|*Ovarian Cancer|*Lectins, C-Type|*Receptors, Cell Surface|Cystadenocarcinoma, Serous|*Ovary|Cell Proliferation|Epithelial-Mesenchymal Transition|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Signaling|Biomarkers, Tumor|Upregulation|Phenotype 29 LYAR 26897028 Mol Diagn Ther 2016 10.1007/s40291-016-0187-2 4 0 0 134 *Fetal Hemoglobin|Thalassemia Major|gamma-Globins|*Thalassemia|*Polymorphism, Genetic|Mutation|Haplotypes|Pedigree|Promoter Regions, Genetic|Iran|Egypt|Iraq 32 LYL1 27851970 Cell Rep 2016 10.1016/j.celrep.2016.08.082 16 24 0 118 Humans|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|RUNX1 Translocation Partner 1 Protein|*Leukemia, Myeloid, Acute|Oncogene Proteins, Fusion|*Apoptosis|Translocation, Genetic|*Oncogene|Acetylation|*Hematopoietic System|Cell Differentiation|Cell Proliferation|Cell Line, Tumor|Promoter Regions, Genetic|Hematopoietic Stem Cell Transplantation|ERG protein, human|Transcriptional Regulator ERG|AML1-ETO fusion protein, human 92 LYL1 27191957 PLoS ONE 2016 PMC4871414 10.1371/journal.pone.0155408 5 22 1 118 Humans|Mice|Animals|*Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|*Cell Transformation, Neoplastic|Intracellular Signaling Peptides and Proteins|CCAAT-Enhancer-Binding Proteins|Protein-Serine-Threonine Kinases|Cell Proliferation|Oncogenes|Hematopoiesis|Cell Differentiation|Signal Transduction|Cell Lineage|Mice, Knockout|TRIB2 protein, human|Calcium-Calmodulin-Dependent Protein Kinases|Tlx1 protein, mouse|Homeodomain Proteins 92 LYL1 27137657 Curr. Top. Dev. Biol. 2016 10.1016/bs.ctdb.2016.01.004 14 2 0 118 *Cellular Reprogramming|*Hematopoiesis|LYL1 protein, human|Basic Helix-Loop-Helix Transcription Factors|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|T-Cell Acute Lymphocytic Leukemia Protein 1|GATA1 protein, human|GATA1 Transcription Factor|GATA2 protein, human|GATA2 Transcription Factor|LIM Domain Proteins|Neoplasm Proteins|Cell Differentiation|Proto-Oncogene Proteins|Hematopoietic Stem Cells|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Thymocytes 92 LYL1 27050553 PLoS ONE 2016 PMC4822879 10.1371/journal.pone.0152384 0 5 1 118 Humans|CD14 Antigen|Monocytes|Dendritic Cells|Antigen Presentation|Lymphocyte Activation|CD8-Positive T-Lymphocytes|Cell Differentiation|*Cell Count|Granulocyte-Macrophage Colony-Stimulating Factor|Lentivirus|MelanA|T-Cell Epitopes|Flow Cytometry 92 MAGEC1 27581737 J. Cancer Res. Clin. Oncol. 2016 10.1007/s00432-016-2231-3 2 0 0 33 Humans|Male|*Multiple Myeloma|Pilot Projects|*Testis|*Neoplastic Cells, Circulating|Plasma Cells|Antigens, Neoplasm|Neoplasm Proteins|*Testicular Neoplasms|Bone Marrow|Flow Cytometry|Biomarkers, Tumor|Cell Line, Tumor|Stem Cell 67 MAGEC1 27165065 Bull. Exp. Biol. Med. 2016 10.1007/s10517-016-3315-4 1 0 0 33 *Neural Cell Adhesion Molecule L1|*Wnt Signaling Pathway|Melanoma|Antigens, Neoplasm|Neoplasm Proteins|*Genes, Class I|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Antibodies, Monoclonal 67 MAGEC1 26822197 BMC Genet. 2016 PMC4895599 10.1186/s12863-015-0308-7 6 11 1 33 Humans|*Prognosis|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|*Oncogenes|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Mutation|Sequencing, Whole Exome 67 MAP3K10 26748257 Behav. Brain Res. 2016 10.1016/j.bbr.2015.12.033 2 1 0 161 Animals|Mice|*C57BL Mouse|*Protein Kinases|*Phosphatases|*Proteomics|Fear|Memory|Conditioning, Classical|Hippocampus|Electroshock|*Phobic Disorders|CaM KII|Signal Transduction 61 MAP6 27541346 Psychiatry Res 2016 10.1016/j.psychres.2016.08.024 4 0 0 2068 Animals|Humans|Mice|*Autistic Disorder|*C57BL Mice|Proteomics|*Microtubule-Associated Proteins|Microtubule|Mice, Inbred Strains|Disease Models, Animal|Cerebral Cortex|*Plasma|MAP6 protein, human 78 MAP6 27255271 BMC Cancer 2016 PMC4891845 10.1186/s12885-016-2371-5 6 2 1 2068 Humans|Quality of Life|*Oral Leukoplakias|*Promoter Regions, Genetic|Mouth Neoplasms|Squamous Cell Carcinomas|CpG Islands|DNA Methylation|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Cell Transformation, Neoplastic 78 MAP6 27218831 Bipolar Disord 2016 10.1111/bdi.12395 4 0 0 2068 *Bipolar Disorder|*White Matter|*Schizophrenia|*Axons|Prefrontal Cortex|Neurons 78 MAP9 27930654 PLoS Genet. 2016 PMC5145144 10.1371/journal.pgen.1006469 16 8 0 342 Humans|Animals|*Cilia|Caenorhabditis elegans|*GTPase|Bardet-Biedl Syndrome|*Protein Transport|Caenorhabditis elegans Proteins|Dynein|Flagella|Biological Transport|Retinitis Pigmentosa|Signal Transduction|Mutation|FAM161A protein, human|Eye Proteins|Rab-28 protein, C elegans|rab GTP-Binding Proteins 26 MAP9 27017229 Mamm. Genome 2016 10.1007/s00335-016-9627-x 7 1 0 342 Dogs|Animals|Late-Onset Retinal Degeneration|*Retinal Degeneration|Genome-Wide Association Study|Retinitis Pigmentosa|Cone Rod Dystrophy|Homozygote|Pedigree|Electroretinography|Phenotype|Mutations|Exon|Haplotypes|Retina|Dog Diseases 26 MAP9 26883180 Oncol. Rep. 2016 10.3892/or.2016.4619 18 0 0 342 *Carcinoma, Hepatocellular|*DNA Methylation|*Liver Neoplasms|*B-DNA|CpG Islands|Promoter Regions, Genetic|Oligonucleotide Array Sequence Analysis|Decitabine|Epigenesis, Genetic|Azacitidine|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Downregulation|Cell Line, Tumor|Gene Silencing|Genes, p16 26 MATN2 27462267 Front Aging Neurosci 2016 PMC4941795 10.3389/fnagi.2016.00171 3 14 1 125 Humans|*Apo E-4|*Alzheimer Disease|*Heterozygote|Apolipoproteins E|Gene Frequency|Genotype|Alleles|Polymorphism, Genetic|Genetic Predisposition to Disease|Parkinson Disease|Risk Factors|Apo E-3|Xpo4 protein, human|Karyopherins|RASD2 protein, human|GTP-Binding Proteins|RIN1 protein, human|Intracellular Signaling Peptides and Proteins 55 MATN2 27035928 Int. J. Mol. Med. 2016 10.3892/ijmm.2016.2534 10 0 0 125 Humans|*Thyroid Cancers|Thyroid Nodules|Biopsy, Fine-Needle|Thyroid Gland|Cytodiagnosis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Genes, Regulator|RNA, Messenger|Diagnosis, Differential|Gene Expression|Genes, cdc|*Biomarkers|MATN2 protein, human|Matrilin Proteins 55 MCM9 27886675 Cancer Genet 2016 10.1016/j.cancergen.2016.10.001 1 0 0 93 Humans|*Lynch Syndrome|Australia|DNA Mismatch Repair|Germline Mutation|Instability, Microsatellite|MutL Protein Homolog 1|Nuclear Proteins|Adaptor Proteins, Signal Transducing|Genetic Predisposition to Disease|DNA Helicases|Mutations|*Germ Line|MCM9 protein, human|Minichromosome Maintenance Proteins 45 MCM9 27802094 J. Clin. Endocrinol. Metab. 2016 PMC5413161 10.1210/jc.2016-2565 14 0 0 93 Humans|Female|*Primary Ovarian Insufficiency|MCM9 protein, human|*Minichromosome Maintenance Proteins|MCM8 protein, human|*Menopause, Premature|Exome|Pedigree|Chromosomal Instability|Polymorphism, Single Nucleotide|*Nucleotides 45 MCTS1 28028797 Histol. Histopathol. 2016 10.14670/HH-11-863 4 0 0 209 *Carcinoma, Renal Cell|SLC2A1 protein, human|*Glucose Transporter Type 1|Neoplasm Recurrence, Local|Monocarboxylic Acid Transporters|Symporters|Basigin|Prognosis|Immunohistochemistry|Biomarkers, Tumor|Muscle Proteins|Kidney Neoplasms 66 MCTS1 27294876 Nat. Med. 2016 10.1038/nm.4128 30 2 1 209 Lenalidomide|pomalidomide|Thalidomide|Multiple Myeloma|Immunologic Factors|Myelodysplastic Syndrome|*Teratogenesis|Peptide Hydrolases|Teratogens|Ubiquitin-Protein Ligases|Cell Line, Tumor 66 MCTS1 27239039 Cell Rep 2016 PMC4906373 10.1016/j.celrep.2016.04.090 11 8 1 209 Humans|Mice|Animals|*Protein Biosynthesis|*Peptide Chain Initiation, Translational|MCTS1 protein, human|Oncogene Proteins|Cell Cycle Proteins|Eukaryotic Initiation Factors|mRNA|Open Reading Frames|*Nervous System Malformations|*Protein Processing, Post-Translational|*Proteomics|*Neurogenesis|Mutation 66 METRN 27716826 PLoS ONE 2016 PMC5055347 10.1371/journal.pone.0164446 2 5 1 47 Humans|*Osteogenesis|*Cell Differentiation|Osteoblasts|*Bone|Transcription Factor|Osteocytes|Transcription, Genetic|Chondrocytes|DNA-Binding Proteins|Cell Line|Gene Expression Regulation|Cell Proliferation|Signal Transduction|Osteosarcoma 22 METRN 27669446 Med Sci Sports Exerc 2016 PMC5491706 10.1249/MSS.0000000000001095 5 1 0 47 Humans|Yukon Territory|Brown Fat|Body Composition|Physical Endurance|Body Mass Index|Energy Metabolism|Exercise|Muscle, Skeletal|Adipokines|Fibronectins 22 METRN 27063217 Acta Pharmacol. Sin. 2016 PMC4857552 10.1038/aps.2016.9 17 23 1 47 Adipose Tissue, White|Adipokine|Adipose Tissue, Brown|Adiposity|Obesity|Nerve Growth Factors|Nerve Tissue Proteins|Signal Transduction|Insulin 22 MIEN1 27589566 Oncotarget 2016 PMC5323157 10.18632/oncotarget.11675 3 12 0 102 Humans|Male|Epigenesis, Genetic|*Promoter Regions, Genetic|*Short Interspersed Nucleotide Elements|DNA Methylation|Neoplasm Proteins|Cell Migration|Alu Element|*Protein Processing, Post-Translational|Intracellular Signaling Peptides and Proteins|RNA Interference|Cell Line, Tumor|DNA Modification Methylases|Transcription Start Site|Prostate Cancer|MIEN1 protein, human 33 MIEN1 27462783 Oncotarget 2016 PMC5342390 10.18632/oncotarget.10798 8 33 0 102 *Focal Adhesions|*Cell Adhesion|*Cytoskeleton|Cell Migration|Phosphorylation|Actin Cytoskeleton|Actin|Focal Adhesion Kinase 1|Neoplasm Proteins|Cell Line, Tumor|Intracellular Signaling Peptides and Proteins|Signal Transduction|Microfilament Proteins 33 MIEN1 27194589 Biosci Trends 2016 10.5582/bst.2016.01025 1 1 0 102 Humans|*Simvastatin|*Downregulation|*Colon Cancer|Cell Proliferation|HT29 Cells|*Colon|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Apoptosis|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Oncogenesis|mRNA 33 MIEN1 26827826 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.01.163 14 7 0 102 *Carcinoma, Non-Small-Cell Lung|*Matrix Metalloproteinase 9|*Vascular Endothelial Growth Factor A|*VEGF-B|*Lung Neoplasms|MicroRNAs|Neoplasm Invasiveness|Downregulation|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|NF-kappa B|Cell Proliferation|Signal Transduction|Upregulation 33 MIEN1 26781796 Biosci Trends 2016 10.5582/bst.2015.01161 1 0 0 102 Humans|Female|*Lymphatic Metastasis|ERBB2 protein, human|Receptor, ErbB-2|Receptors, Progesterone|Receptors, Estrogen|Carcinoma, Ductal, Breast|Immunohistochemistry|Neoplasm Proteins|*Neoplastic Processes|*Carcinomas, Breast 33 MIPEP 27799064 Genome Med 2016 PMC5088683 10.1186/s13073-016-0360-6 6 8 1 43 Humans|*Muscle Hypotonia|PITRM1 protein, human|Metalloendopeptidases|*Syndrome|Exome|Pedigree|*Heart Ventricles|Mitochondria|Mutation 29 MIR135B 27176897 Mol Med Rep 2016 PMC4918533 10.3892/mmr.2016.5268 10 6 1 0 Humans|Pregnancy|Female|*Pre-Eclampsia|*Placenta|RNA, Micro|Gene Expression Profiling|Upregulation|Ion Torrent Sequencing|Hypertension 26 MIR135B 27113293 Sci Rep 2016 PMC4844987 10.1038/srep25066 12 39 1 0 Humans|*Interleukin-13|*Collagen|Fibroblasts|Sclerosis, Systemic|STAT6 protein, human|*STAT6 Transcription Factor|Collagen Type I|Dermis|MicroRNAs|*Epigenesis, Genetic|RNA, Small Interfering|Skin|Transfections|Cells, Cultured|Signal Transduction|*Epigenetics 26 MIR135B 27042261 Oxid Med Cell Longev 2016 PMC4799823 10.1155/2016/3859721 0 11 1 0 Humans|*Keratinocytes|*Collagen Type IV|*Phlorhizin|*Eleutherococcus|Skin|Epidermis|Stem Cells|Cells, Cultured|Cell Proliferation|Proliferating Cell Nuclear Antigen|Integrin beta1|Integrins|Antioxidants 26 MIR135B 26781873 Tumour Biol. 2016 10.1007/s13277-016-4824-5 14 0 0 0 Humans|*Stomach Neoplasms|*Cardia|*Adenocarcinoma|MicroRNAs|Gene Expression Regulation, Neoplastic|Prognosis|Biomarkers, Tumor|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Lymphatic Metastasis|RNA, Messenger|Real-Time Polymerase Chain Reaction|Downregulation|Upregulation 26 MLLT11 27510506 Mol. Neurobiol. 2016 10.1007/s12035-016-9954-7 3 2 0 143 Humans|Haplotype|Single Nucleotide Polymorphisms|TXNIP protein, human|*Carrier Proteins|*Schizophrenia|Genetic Predisposition to Disease|Epistasis, Genetic|Allele|Linkage Disequilibrium|Genotype|Genetic Association Studies|Gene Frequency|Case-Control Studies|Transcription Factors 40 MLLT11 27282883 Hematol Oncol 2016 10.1002/hon.2299 1 0 0 143 Child|Humans|KMT2A protein, human|*Myeloid-Lymphoid Leukemia Protein|*Histone-Lysine N-Methyltransferase|*Karyotypes|*Karyotyping|*Gene Fusion|Leukemia, Myeloid, Acute|Translocation, Genetic|Oncogene Proteins, Fusion|Transcription Factors|Gene Rearrangement|Acute Lymphoblastic Leukemia|Nuclear Proteins|Chromosome Aberrations|Prognosis|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins 40 MLLT11 27259262 Oncotarget 2016 PMC5190071 10.18632/oncotarget.9759 11 66 1 143 Mice|Animals|STAT3 protein, human|*STAT3 Transcription Factor|PDGF receptor tyrosine kinase|*Platelet Derived Growth Factor Receptor|*Signal Transduction|src Kinases|Tyrosine Kinase|Cell Movement|Phosphorylation|Proto-Oncogene Proteins c-sis|Proto-Oncogene Proteins|Cell Line, Tumor 40 MLLT11 26913079 Mol Cytogenet 2016 PMC4765068 10.1186/s13039-016-0227-y 9 1 1 143 *Wilms Tumor|*Oncogenes|*Genomics|DNA Copy Number Variations|Comparative Genomic Hybridization|Loss of Heterozygosity|Chromosome Aberrations|Kidney Neoplasms 40 MLLT11 26788135 Oncol Lett 2016 PMC4665311 10.3892/ol.2015.3761 2 1 1 143 Humans|Child|Bayes Theorem|Network, Gene|Protein Interaction Maps|Gene Expression Profiling|Computational Biology|Databases, Genetic|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Epistasis, Genetic|Algorithm|Signal Transduction|Transcription Factors|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins 40 MORC1 27791268 J. Cell. Physiol. 2016 10.1002/jcp.25665 6 0 0 59 Mice|Male|Animals|Epigenesis, Genetic|*Cancer|Nuclear Protein|Spermatogenesis|*Bone|*Homeostasis|Signal Transduction|MORC3 protein, mouse|Adenosine Triphosphatases|DNA-Binding Proteins 26 MORC1 27482822 Mol. Plant Microbe Interact. 2016 10.1094/MPMI-01-16-0023-R 4 1 0 59 *Arabidopsis|*DNA Transposable Elements|*Chromatin|Pseudomonas syringae|Arabidopsis Proteins|Plant Immunity|Gene Expression Regulation, Plant|Plant Diseases|Genes, Plant|Tomato|Epigenesis, Genetic|Infections 26 MORC1 27362276 RNA Biol 2016 PMC5013992 10.1080/15476286.2016.1191738 5 3 0 59 *Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Transcription Factors|Gene Expression Regulation, Fungal|DNA-Binding Proteins|*Protein Isoforms|Meiosis|Nuclear Proteins|Repressor Proteins|Spores, Fungal|Mitosis|Promoter Regions, Genetic|Mitogen-Activated Protein Kinases|Gene Activation|NDT80 protein, S cerevisiae|SUM1 protein, S cerevisiae|ORC1 protein, S cerevisiae|Origin Recognition Complex 26 MORC1 27216319 Mol Plant 2016 10.1016/j.molp.2016.05.006 8 2 0 59 *Arabidopsis|Arabidopsis Proteins|*Gene Silencing|DNA Methylation|Gene Expression Regulation, Plant|Heterochromatin|Histone-Lysine N-Methyltransferase|ATPases|Transcription Factors|Chromatin|Histones|RNA, Small Interfering|SUVH2 protein, Arabidopsis|SUVH9 protein, Arabidopsis 26 MORC1 26933034 J. Biol. Chem. 2016 PMC4861470 10.1074/jbc.M116.718973 13 0 0 59 Humans|*Histones|*Protein Binding|Histone-Lysine N-Methyltransferase|Modifications, Histone|Methylation|Binding Sites|Amino Acid Sequence|Crystallography, X-Ray|Protein Processing, Post-Translational|Models, Molecular 26 MORC1 26740066 Mol. Hum. Reprod. 2016 10.1093/molehr/gav072 6 1 1 59 Mice|Animals|*Transcriptome|*Embryo, Mammalian|Epiblast|*Implantation, Embryo|Endoderm|Blastocyst|*Germ Cells|Cell Lineage|Cell Differentiation|Signal Transduction|Tcfap2c protein, mouse|Transcription Factor AP-2 26 MPZL2 26930581 PLoS ONE 2016 PMC4773014 10.1371/journal.pone.0147489 11 28 3 144 Humans|Animals|Epithelial-Mesenchymal Transition|*Cell Differentiation|CLCA2 protein, human|*Chloride Channels|CTNNB1 protein, human|beta Catenin|MCF-7 Cells|Cells, Epithelial|CDH1 protein, human|E Cadherin|Cell Line, Tumor|Cell Adhesion|Downregulation|Antigens, CD|*Organogenesis 22 MTX3 27885668 J. Phycol. 2016 10.1111/jpy.12496 9 0 0 133 Mice|Animals|*Dinoflagellate|Phylogeny|Gas Chromatography-Mass Spectrometry|maitotoxin|Oxocins|Marine Toxins|Ciguatoxins|Ciguatera Fish Poisoning|Chromatography, Liquid|Australia|Islands 21 MXD1 27588501 Oncotarget 2016 PMC5342496 10.18632/oncotarget.11766 4 17 0 873 Humans|*Cell Nucleolus|*Transcription, Genetic|Pol1 Transcription Initiation Complex Proteins|rDNA|RNA, Ribosomal|Pre-rRNA|Ribosomes|siRNA|Chromatin|Protein Binding|HeLa Cells|Chromatin Immunoprecipitation|MXD1 protein, human|Repressor Proteins|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors 172 MXD1 27588137 Oncol Lett 2016 PMC4998008 10.3892/ol.2016.4881 5 11 1 873 Humans|RNA, Micro|*Lung Cancer|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Lentivirus|MXD1 protein, human|Repressor Proteins|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors 172 MXD1 27579147 Genes Nutr 2016 PMC4971612 10.1186/s12263-016-0538-y 0 5 1 873 Humans|Animals|*Alaska Natives|*Vitamin D|*Parathyroid Hormone|Diet|Vitamin D Deficiency|*Genetic Linkage|Inuits|*Vitamins|Fatty Acids, Omega-3|Cross-Sectional Studies|*Cholestanes|Alaska 172 MXD1 27520398 Stem Cells Dev. 2016 10.1089/scd.2016.0150 5 0 0 873 Humans|*Down-Regulation|Megakaryocytes|MicroRNAs|Hematopoietic Stem Cells|Cell Differentiation|3' Untranslated Region|Cell Lineage|mRNA|RNA Interference|Antigens, CD34|*Hematopoiesis|GATA2 protein, human|GATA2 Transcription Factor|Gene Expression Profiling|Myelopoiesis|Granulocyte|Upregulation|MXD1 protein, human 172 MXD1 27497986 Cell. Physiol. Biochem. 2016 10.1159/000447797 14 0 0 873 Humans|Female|*Niclosamide|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Signal Transduction|Antineoplastic Agents|Cell Proliferation|Receptor, IGF Type 1|Xenograft Model Antitumor Assays|Cell Cycle|*Anthelmintics|Apoptosis|Cell Line, Tumor|Cell Movement|Gene Expression Regulation, Neoplastic 172 MXRA5 27599751 J. Cell. Mol. Med. 2016 PMC5192817 10.1111/jcmm.12953 9 20 1 21 Humans|*Fibrosis|TGFBR1 protein, human|TGFBR1|Transforming Growth Factor beta1|Epithelial Cells|Kidneys|*Transforming Growth Factor|Up-Regulation|Kidney Tubules|Cell Line|Signal Transduction|Downregulation|Protein-Serine-Threonine Kinases|RNA Interference|Carcinoma, Renal Cell|paricalcitol|Ergocalciferols|Kidney Neoplasms 23 MXRA5 27513329 PLoS ONE 2016 PMC4981437 10.1371/journal.pone.0161007 7 15 1 21 Humans|thrombospondin 2|*Thrombospondin 1|*Lung Cancer|Lung Carcinoma, Non-Small-Cell|*Thrombospondins|Squamous Cell Carcinoma|Adenocarcinoma|Prognosis|Neoplasm Staging|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Genes, Regulator|Survival Rates|Lung Adenocarcinoma|Gene Expression Profiling|Real-Time Polymerase Chain Reaction|mRNA|Microarray Analysis 23 MYH15 27982099 Sci Rep 2016 PMC5159859 10.1038/srep39398 18 3 0 40 Female|Sheep|Animals|*Long Non-Coding RNA|*Ovary|*Fecundity|Gene Expression Profiling|Sheep, Domestic|Transcriptome|Gene Regulatory Networks|RNA, Messenger 24 MYH15 26970499 Ann. Anat. 2016 10.1016/j.aanat.2016.02.007 7 1 0 40 Animals|Humans|Myosin Heavy Chain|*Isoforms|*Sarcomeres|Muscle Fibers, Slow-Twitch|*Skeletal Muscles|Muscle Fibers, Fast-Twitch|Extraocular Muscles|*Mammals|SDS PAGE|Western Blot|mRNA|Laryngeal Muscles|Real-Time PCR, Quantitative 24 MYO18B 27900359 Cold Spring Harb Mol Case Stud 2016 PMC5111006 10.1101/mcs.a001032 3 3 1 35 Humans|Male|Aged|*Homozygote|Checkpoint Kinase 2|Genetic Predisposition to Disease|Germ-Line Mutation|Mutations|Pedigree|Neoplastic Syndromes, Hereditary|Siblings 42 MYO18B 27879346 Genetics 2016 PMC5289847 10.1534/genetics.116.192864 8 0 0 35 Humans|Animals|Mice|*Zebrafish|*Myosin|Zebrafish Proteins|*Myopathy|Sarcomeres|Nemaline Myopathy|Embryo, Nonmammalian|*Mutation|Muscle, Skeletal|Muscle Proteins|Animals, Genetically Modified|Muscle Development|Gene Expression Regulation, Developmental|Myocytes|Actinin|Actin|Phenotype|MYO18B protein, human 42 MYO18B 27441494 Br. J. Cancer 2016 PMC4985359 10.1038/bjc.2016.219 9 0 1 35 Humans|*Barrett Esophagus|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Precancerous Conditions|*Disease Progression|Genes, p53|Biomarkers, Tumor|Mutations|Immunohistochemistry|Biopsy|Point Mutations 42 MYO18B 26760505 Oncotarget 2016 PMC4872754 10.18632/oncotarget.6845 5 2 1 35 Humans|Mice|Animals|*Gene Amplification|*Myogenesis|Myoblasts|*Cell Differentiation|Muscle Fibers, Skeletal|Cell Fusion|Neural Stem Cells|Cell Line|Genes, cdc 42 myo1f 27934915 Sci Rep 2016 PMC5146968 10.1038/srep38803 14 1 0 128 Humans|Floating-harbor syndrome|*DNA Methylation|*Craniofacial Abnormalities|*Abnormalities, Multiple|*Heart Septal Defects, Ventricular|*Growth Disorders|Mutations|Dwarfism|Adenosine Triphosphatases|*Nucleotide Motifs|CpG Islands|Face|Chromatin|MYO1F protein, human|Myosin Type I 25 myo1f 26907498 Genome Biol Evol 2016 PMC4824011 10.1093/gbe/evw032 19 9 1 128 Animals|*Chickens|*Altitude|Tibet|*Ultraviolet Rays|*Acclimatization|*Genome|*Adaptation, Physiological|*Hypoxia|Frequencies, Allele|Genetics, Population|*Environment|Single Nucleotide Polymorphisms|Oxygen 25 myo1f 26801966 Cytoskeleton (Hoboken) 2016 PMC4769671 10.1002/cm.21275 7 8 1 128 *Myosin I|*Actins|Dictyostelium|Myosins|Actin Cytoskeleton|Plasma Membrane|Cell Membrane Structures|Cytoskeletal Proteins|Cell Migration|Endocytosis|Protein Binding|Binding Sites|*Endosomes 25 MYO5C 27498562 Curr. Biol. 2016 PMC4996695 10.1016/j.cub.2016.06.029 5 5 0 604 Humans|Myosin Type V|Filaments, Actin|Actin|Myosin Heavy Chains|*Biological Transport|Kinetics|*Biochemical Phenomena|Adenosine Triphosphate 22 MYO5C 26912658 J. Biol. Chem. 2016 PMC4825024 10.1074/jbc.M115.693762 3 5 0 604 Animals|MYO5A protein, human|*Myosin V|*Myosin Heavy Chains|*Myosin|Adenosine Triphosphatases|*Isoforms|Calmodulin|Models, Molecular 22 MZB1 27459504 Int. J. Cancer 2016 10.1002/ijc.30286 8 3 0 35 Humans|*Stomach Neoplasms|Neoplasm Recurrence, Local|DNA Methylation|Promoter Regions, Genetic|Prognosis|CpG Islands|Gene Expression Regulation, Neoplastic|Gastric Mucosa|Biomarkers, Tumor|Gastrectomy|*Phenotype|Transcriptome Analysis|Tumor Suppressor Proteins|mRNA|*Epigenetic|Cell Line, Tumor|Epigenesis, Genetic 25 NCAM2 27221037 Oncotarget 2016 PMC5122410 10.18632/oncotarget.9535 6 17 1 77 Humans|Male|MDV 3100|AR protein, human|*Receptors, Androgen|*Prostatic Neoplasms, Castration-Resistant|*Phenylthiohydantoin|Androgen Antagonists|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|Xenograft Model Antitumor Assays|Signal Transduction|Downregulation|Apoptosis|*RNA|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 71 NCAM2 27596683 Eur J Med Genet 2016 10.1016/j.ejmg.2016.08.006 1 0 0 77 Humans|Male|Child|*Autistic Disorder|Autism Spectrum Disorder|*Macrocephaly|NCAM2 protein, human|*Neural Cell Adhesion Molecule L1|Speech Delay|*Genotype|Chromosome Deletion|*Disease Susceptibility 71 NCAM2 27375131 Am. 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Bowel Dis. 2016 PMC5220246 10.1097/MIB.0000000000000705 3 3 0 108 *Crohn Disease|Quality of Life|*Disease, Colonic|*Stricture|Anus Diseases|*DNA Mutational Analysis|Genetic Variation 24 NEUROD4 27922636 Transl Psychiatry 2016 PMC5315565 10.1038/tp.2016.247 13 5 0 53 Child|Humans|Pregnancy|Female|Adolescent|Male|*DNA Methylation|*Prospective Studies|*Genome-Wide Association Study|Longitudinal Studies|*B-DNA|Gene Regulatory Networks|Processes, Epigenetic|CpG Islands|Epigenetic|Prenatal Exposure Delayed Effects|Quantitative Trait Loci|*Substance-Related Disorders|Smoking|Blood, Cord 59 NEUROD4 27631552 Endocrinology 2016 PMC5086538 10.1210/en.2016-1372 3 0 0 53 Somatotrophs|Cell Differentiation|Pituitary Gland|Homeodomain Proteins|Transcription Factor|Hypopituitarism|Growth Hormone 59 NEUROD4 27387288 PLoS ONE 2016 PMC4936704 10.1371/journal.pone.0158210 3 4 1 53 Animals|Hedgehog Proteins|*Zebrafish|*Habenula|*Neurogenesis|Body Patterning|Zebrafish Proteins|Signal Transduction|Diencephalon|Gene Expression Regulation, Developmental|Transcription Factor|NEUROG1 protein, human|Nerve Tissue Proteins|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Embryo, Nonmammalian|Neurons|neurod4 protein, zebrafish 59 NEUROD6 27762319 Sci Rep 2016 PMC5071886 10.1038/srep35203 11 2 1 73 Humans|Mice|Animals|*Dopamine|*Parkinson Disease|*Mesencephalon|Tegmental Area, Ventral|Dopaminergic Neurons|Substantia Nigra Pars Compacta|Optogenetics|Glutamate|Neurod6 protein, mouse|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 84 NEUROD6 27559164 J. Neurosci. 2016 PMC4995298 10.1523/JNEUROSCI.1224-16.2016 8 0 0 73 Mice|Animals|*Somatosensory Cortex|GRM5 protein, human|*Receptor 5, Metabotropic Glutamate|*Neurons|Vibrissae|Neurotransmission|Whole-Cell Recordings|Axons|Thalamus|Synapses|Neural Pathways|Glutamate|Mice, Knockout|Nerve Tissue Proteins 84 NEUROD6 27358460 J. Neurosci. 2016 PMC4926245 10.1523/JNEUROSCI.4280-15.2016 2 1 0 73 Mice|Animals|Action Potentials|Somatosensory Cortex|Neuronal Plasticity|Long-Term Potentiation|Receptors, N-Methyl-D-Aspartate|Neurons|Axons|Thalamus|*Cannabinoids 84 Nfkbil1 27875997 BMC Infect. Dis. 2016 PMC5120459 10.1186/s12879-016-2044-7 0 6 0 46 Humans|*Hepatitis C virus|*Coinfection|*HIV Infections|*Hepatitis C|Hepatitis C, Chronic|Viral Load|RNA, Viral 67 Nfkbil1 29744169 Clin Exp Dent Res 2016 PMC5839215 10.1002/cre2.40 3 2 0 46 Humans|Adolescent|*Periodontitis|*Polymorphism, Genetic|Periodontal Pocket|Periodontal Index|Smoking|Inflammation Mediators|Finland 67 NFX1 27311997 J. Biochem. 2016 PMC5892129 10.1093/jb/mvw038 0 2 0 98 Humans|*Protein Kinase C|Promoter Regions, Genetic|Telomerase|Transcription, Genetic|Transcription Factors|Repressor Proteins|Histone Deacetylases|Cell Line|Cellular Senescence|RNA, Messenger|Cells, Cultured|NFX1 protein, human 45 NFX1 27053962 J Neurodev Disord 2016 PMC4822306 10.1186/s11689-016-9146-9 1 0 1 98 *Specific Language Disorder|Transcription Factor|Amino Acid Sequence 45 NHLH1 27559308 Front Cell Neurosci 2016 PMC4988241 10.3389/fncel.2016.00186 4 25 1 132 Mice|Animals|Wnt Proteins|beta Catenin|*Neurogenesis|Wnt Signaling Pathway|Hair Cells, Auditory|Cell Differentiation|Cochlea|*Epithelium|Receptors, G-Protein-Coupled|Stem Cells|Ligands|Animals, Newborn|Pou4f3 protein, mouse|Homeodomain Proteins|Transcription Factor Brn-3C|Lgr5 protein, mouse|LGR4 protein, mouse 43 NHLH1 27149122 PLoS Genet. 2016 PMC4858216 10.1371/journal.pgen.1006034 11 3 1 132 Humans|Genome-Wide Association Study|HEK293 Cells|*Heart Failure|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Allele|Genetic Loci|African Americans|Case-Control Studies|Gene Expression Regulation|Epigenomic|Transcription Factor|*Chromosome 43 NLRP5 27611906 PLoS ONE 2016 PMC5017692 10.1371/journal.pone.0162722 7 6 1 64 Female|Animals|Mice|*Histones|*Methylation|*Oocytes|Ovulation|*Aging|Ovarian Follicle|Oogenesis|Spindle Apparatus|Cellular Senescence|*Protein Processing, Post-Translational|Ybx2 protein, mouse|RNA-Binding Proteins 65 NLRP5 27525657 J. 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Genet. 2016 PMC5125147 10.1007/s10815-016-0788-z 7 0 0 64 Humans|Animals|Oocytes|Zygote|Blastocyst|Embryonic Development|*Cytoplasm|Embryo, Mammalian|Gene Expression Regulation, Developmental|Amino Acid Sequence|Transcription Factors|Protein Binding|RNA, Messenger|Divisions, Cell 65 NPAS1 27827370 Neuropsychopharmacology 2016 PMC5506786 10.1038/npp.2016.251 7 18 0 55 Mice|Animals|*Globus Pallidus|*Ethanol|*Neurons|Action Potentials|Receptor Antagonists, Glutamate|*Pacemaker, Artificial|Npas1 protein, mouse|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 35 NPAS1 27782878 Elife 2016 PMC5111884 10.7554/eLife.18790 16 19 0 55 Humans|Animals|*Aryl Hydrocarbon Receptor Nuclear Translocator|*Protein Binding|*Ligands|Basic Helix-Loop-Helix Transcription Factors|Protein Domain|Dimerization|Protein Multimerization|DNA|Crystallography, X-Ray|Models, Molecular|Gene Expression Regulation|NPAS1 protein, human|Nerve Tissue Proteins|ARNT protein, human|NPAS3 protein, human|Transcription Factors 35 NPAS1 27194328 J. Neurosci. 2016 PMC4871984 10.1523/JNEUROSCI.1720-15.2016 21 0 0 55 Mice|Animals|*Pallidum|*Corpus Striatum|*Neurons|Mice, Transgenic|Basal Ganglia|Neural Pathways|Parkinson Disease|*Interneurons|Optogenetics|Npas1 protein, mouse|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors 35 NPAS1 26841063 Eur. J. Neurosci. 2016 PMC4874844 10.1111/ejn.13196 29 24 1 55 *Globus Pallidus|Subthalamic Nucleus|Basal Ganglia|Neurons|Neural Pathways|Parkinson Disease 35 Npas3 27877109 Front Mol Neurosci 2016 PMC5099284 10.3389/fnmol.2016.00109 4 31 1 39 Rats|Animals|*Neurogenesis|Nerve Cells|BDNF protein, human|Brain-Derived Neurotrophic Factor|Basic Helix-Loop-Helix Transcription Factors|Nerve Tissue Proteins|Transcription Factors|Hippocampus|Signal Transduction|NGF protein, human|Nerve Growth Factor|PC12 Cells|Promoter Regions, Genetic|Receptors, Glutamate|Cell Proliferation|*Psychiatric Illnesses 56 Npas3 27867938 Mol Neuropsychiatry 2016 PMC5109994 10.1159/000447358 5 2 0 39 Animals|*Protein Aggregates|*Schizophrenia|*Mutation|Nerve Tissue Proteins|Transcription Factors|Amyloidosis, Hereditary, Transthyretin-Related|Amyloid Neuropathies, Familial|Isoleucine 56 Npas3 27782878 Elife 2016 PMC5111884 10.7554/eLife.18790 16 19 0 39 Humans|Animals|*Aryl Hydrocarbon Receptor Nuclear Translocator|*Protein Binding|*Ligands|Basic Helix-Loop-Helix Transcription Factors|Protein Domain|Dimerization|Protein Multimerization|DNA|Crystallography, X-Ray|Models, Molecular|Gene Expression Regulation|NPAS1 protein, human|Nerve Tissue Proteins|ARNT protein, human|NPAS3 protein, human|Transcription Factors 56 Npas3 27288358 Mol. Cancer Res. 2016 10.1158/1541-7786.MCR-15-0395 9 6 0 39 Humans|*Tongue Neoplasms|*DNA Methylation|*B-DNA|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Oral Cancer|Lymphatic Metastasis|Neoplasm Staging|Epigenesis, Genetic|Promoter Regions, Genetic|Lymph Nodes|Gene Expression Regulation, Neoplastic|MAP3K8 protein, human|Proto-Oncogene Proteins|MAP Kinase Kinase Kinases|Cohort Studies 56 Npas3 27096574 J Dev Behav Pediatr 2016 10.1097/DBP.0000000000000302 2 0 0 39 Child|Humans|Female|Animals|*Dolphins|Comparative Genomic Hybridization|*Psychosis|*Cognitive Decline|Hallucinations|Risperidone|Antipsychotic Agents|Intellectual Disability|Intelligence|Anticonvulsants 56 Npas3 26902966 Sci Rep 2016 PMC4763269 10.1038/srep22124 4 0 1 39 Humans|Male|Mice|Rats|Animals|Neoplasm Recurrence, Local|*Prostate Cancer|Prostatectomy|Single Nucleotide Polymorphisms|Prognosis|Genetic Predisposition to Disease|Proportional Hazards Models|Genotype|Neoplasm Staging|Kaplan-Meier Estimate 56 Npas3 26871630 Cell 2016 PMC4752721 10.1016/j.cell.2015.12.039 75 1 1 39 *B-DNA|DNA Breaks, Double-Stranded|DNA End-Joining Repair|*Neural Stem Cells|DNA Repair|Aphidicolin|Neurogenesis|DNA-Binding Proteins|DNA|Genome 56 NREP 27927130 Stem Cells Dev. 2016 10.1089/scd.2016.0249 5 7 0 155 Humans|Mice|Animals|RHOA protein, human|*rhoA GTP-Binding Protein|*Epidermal Cells|*Stem Cells|*Re-Epithelialization|cdc42 GTP-Binding Protein|Cell Migration|rac1 GTP-Binding Protein|rho GTPases|Wound Healing|Signal Transduction|Cells, Cultured|Burns|Knockout Mouse|RAC1 protein, human|P311 protein, mouse|Nerve Tissue Proteins 46 NREP 27891769 Diabetes Obes Metab 2016 10.1111/dom.12835 3 0 0 155 Humans|*Exenatide|Diabetes Mellitus, Type 2|Venoms|Glucagon-Like Peptide 1|Hypoglycemic Agents|Glucagon-Like Peptide-1 Receptor|Peptides|Obesity 46 NREP 27806808 J Coll Physicians Surg Pak 2016 2448 1 1 0 155 Animals|Rabbits|*Cicatrix|tetramethylpyrazine|*Constriction, Pathologic|*Fibroblasts|*Pyrazines|Transforming Growth Factor beta1|Cells, Cultured|Actins|RNA, Messenger|Cell Proliferation|Signal Transduction|Blotting, Western 46 NREP 27319780 Nat Commun 2016 PMC4915130 10.1038/ncomms11838 37 0 1 155 Humans|Animals|Mice|Tomography, X-Ray Computed|Doxorubicin|Antibiotics, Antineoplastic|*Positron Emission Tomography|Drug Delivery Systems|Nanoparticles|Polyethylene Glycols|Liposomes|Zirconium-89|Radioisotopes|Drug Compounding|Cell Line, Tumor|Zirconium 46 NUCKS1 27542204 Oncotarget 2016 PMC5308697 10.18632/oncotarget.11297 1 10 0 269 Mice|Animals|Thymus Neoplasms|Tumor Suppressor Protein p53|Lymphoma|Loss of Heterozygosity|Neoplasms, Radiation-Induced|Gene Dosage 35 NUCKS1 26989074 Oncotarget 2016 PMC4991488 10.18632/oncotarget.8011 21 14 1 269 Humans|Mice|Animals|*Cisplatin|*Paclitaxel|*Lung Cancer|MIRN137 microRNA, human|miRNA|Carcinoma, Non-Small-Cell Lung|A549 Cells|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|Cell Proliferation|Antineoplastic Agents|Cell Line, Tumor|Downregulation|Xenograft Model Antitumor Assays|Apoptosis|Mice, Nude|Cell Survival 35 olfm1 27787612 Histochem. Cell Biol. 2016 10.1007/s00418-016-1510-z 0 0 0 101 Animals|Mice|Swine|olfactomedin|Extracellular Matrix Proteins|Glycoproteins|Photoreceptor Cells|Retina|Electroretinography|*Extracellular Matrix|Rhodopsin|Nerve, Optic|TUNEL|Isoforms|Western Blotting 31 olfm1 27555280 J. Pathol. 2016 10.1002/path.4784 7 9 0 101 Humans|olfactomedin|*Colorectal Cancer|*Signal Transduction|Extracellular Matrix Proteins|Cell Proliferation|NF-kappa B|Gene Expression Regulation, Neoplastic|Cell Movement|Downregulation|Biomarkers, Tumor|Cell Line, Tumor|*Neoplastic Processes|Apoptosis|Xenograft Model Antitumor Assays|*Colonic Neoplasms|Protein-Serine-Threonine Kinases|Great Britain|Ireland 31 OLFML3 27684720 Wound Repair Regen 2016 10.1111/wrr.12485 1 0 0 48 Mice|Animals|olfactomedin|*Wound Healing|Extracellular Matrix Proteins|Tissue Engineering|Extracellular Matrix|Tissue Scaffolds|Nanofibers|Biomimetic Materials|Skin|Cell Proliferation|*Plasma 21 OLFML3 26931818 Anim. Genet. 2016 10.1111/age.12413 11 0 0 48 Swine|Animals|Italy|*Adipose Tissue, Subcutaneous|Sus scrofa|Adipose Tissue|Breeding|Meat|Genetic Association Studies|Phenotype|Polymorphism, Single Nucleotide 21 ONECUT2 27756894 Med. Sci. Monit. 2016 PMC5074799 10.12659/msm.897207 5 6 1 153 Humans|*Non-alcoholic Fatty Liver Disease|*Sirtuin 1|MIRN92 microRNA, human|*MicroRNAs|ONECUT2 protein, human|*Transcription Factors|*Homeodomain Proteins|Liver|Hepatocytes|Triglycerides|Hep G2 Cells|Signal Transduction|SIRT1 protein, human 59 OSCP1 27891591 J. Cell. Physiol. 2016 10.1002/jcp.25706 10 7 0 406 Mice|Animals|*Proto-Oncogene Proteins c-akt|*Glycogen Synthase Kinase 3|Mice, Nude|Nasopharyngeal Carcinoma|*Cancer Stem Cells|Nasopharyngeal Neoplasms|Carcinoma|WNT3 protein, human|*Wnt3 Protein|beta Catenin|Antineoplastic Agents|*Catenins|Downregulation|Gene Expression Regulation, Neoplastic|Wnt Signaling Pathway|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Proliferation 62 OSCP1 27181368 Sci Rep 2016 PMC4867575 10.1038/srep25944 3 13 1 406 Humans|*Muscle Protein|Myoblasts|Myotubes|*Cell Differentiation|Muscle Development|Muscle, Skeletal|Transcriptional Activation|*Genes, X-Linked|DNA Binding Protein|*Receptors, Cytoplasmic and Nuclear|Up-Regulation|Promoter Regions, Genetic|SMPX protein, human 62 OSCP1 26934447 Oncotarget 2016 PMC4941348 10.18632/oncotarget.7778 10 42 1 406 Animals|*Epithelial-Mesenchymal Transition|*Slug|*Hepatocyte Nuclear Factor 3-alpha|Nasopharyngeal Carcinoma|HDAC2 protein, human|*Histone Deacetylase 2|Snail Family Transcription Factors|Nasopharyngeal Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|RNA Interference|Cell Line, Tumor|Signal Transduction|Promoter Regions, Genetic 62 OSCP1 26781989 Oncol. Rep. 2016 10.3892/or.2016.4550 3 2 0 406 Humans|Carcinoma, Hepatocellular|*RNA, Micro|*Hep G2 Cells|Liver Neoplasms|*Vascular Endothelial Growth Factor A|*Tumorigenesis|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Cell Transformation, Neoplastic|Downregulation|3' Untranslated Regions|Cell Movement|Upregulation|Cell Line, Tumor 62 OSCP1 26764158 Sci Transl Med 2016 PMC4918505 10.1126/scitranslmed.aad1565 14 73 2 406 Humans|Mice|Animals|*Diacylglycerol Kinase|CD8-Positive T-Lymphocytes|SH2D1A protein, human|Signaling Lymphocytic Activation Molecule Associated Protein|*Lymphoproliferative Disease, X-Linked|Signaling Lymphocytic Activation Molecule Family Member 1|Signaling Lymphocytic Activation Molecule Family|*Cell Death|Epstein Barr Virus Infection|Signal Transduction|Intracellular Signaling Peptides and Proteins|Antigens, CD|B-Lymphocytes|1,2-diacylglycerol|Diglycerides|Pro-Apoptotic Proteins 62 OSR2 27999174 Sci Signal 2016 10.1126/scisignal.aaf6767 4 15 0 68 *Histones|*Euchromatin|Epigenesis, Genetic|Arabidopsis thaliana|Arabidopsis Proteins|Chromatin|Gene Expression Regulation, Plant|Ubiquitination|*Plant Development|Methylation|Transcriptional Activation|Ubiquitin-Specific Proteases|Ubiquitin|Protein Processing, Post-Translational|Endopeptidases|OTLD1 protein, Arabidopsis|Cysteine Proteases 79 OSR2 27870215 Evol. Dev. 2016 10.1111/ede.12208 0 0 0 68 Animals|*Gene Regulatory Networks|*Odontogenesis|*Jaws|*Mandible|Teeth|*Morphogenesis|Vertebrate|Gene Expression Regulation, Developmental|Trans-Activators|Biological Evolution|Phosphoproteins 79 OSR2 27722013 Anat Cell Biol 2016 PMC5052229 10.5115/acb.2016.49.3.199 3 4 1 68 Animals|Mice|*Odontoblasts|SMAD4 protein, human|*Smad4 Protein|*Signal Transduction|*Cell Differentiation|Dentinogenesis|Odontogenesis|Transforming Growth Factor beta|Dentin|Tooth Root|Tooth|Molar|Epithelium 79 OSR2 27713059 Dev. Biol. 2016 PMC5416936 10.1016/j.ydbio.2016.10.001 10 29 0 68 Humans|Mice|Animals|BMP4 protein, human|*Bone Morphogenetic Protein 4|*Tooth|Odontogenesis|MSX1 Transcription Factor|*Signal Transduction|*Organogenesis|Tooth Germ|Transcription Factors|Mesenchyme|Homeodomain Proteins|Gene Expression Regulation, Developmental|Molar|In Situ Hybridization|OSR2 protein, human|MSX1 protein, human|Osr2 protein, mouse 79 oxsr1 27400149 Nat. Immunol. 2016 PMC4994873 10.1038/ni.3495 12 55 1 594 *Cell Adhesion|*T-Lymphocytes|WNK Lysine-Deficient Protein Kinase 1|Transporter, SLC12A2|Protein-Serine-Threonine Kinases|Solute Carrier Family 12, Member 1|Minor Histocompatibility Antigens|Intracellular Signaling Peptides and Proteins|Cell Movement|RNA Interference|Kidney 38 oxsr1 27085470 Mutat Res Genet Toxicol Environ Mutagen 2016 10.1016/j.mrgentox.2016.03.006 7 0 0 594 Humans|*Mustard Gas|*Antioxidants|*Transcriptome|*Oxidative Stress|Chemical Warfare Agents|*Lung|Reactive Oxygen Species|GPX2 protein, human|Glutathione Peroxidase|Lung Diseases|Oxidation-Reduction|FOXM1 protein, human|Forkhead Box Protein M1 38 P2RY8 28033648 Genes Chromosomes Cancer 2016 PMC5396319 10.1002/gcc.22439 12 2 0 46 Humans|CRLF2 protein, human|Cytokine Receptor|*Acute Lymphoblastic Leukemia|Ikaros Transcription Factor|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Gene Expression Regulation, Leukemic|Mutations|Receptors, Purinergic P2Y|*Genomics|Chromosome Aberrations|Down Syndrome 52 P2RY8 27959929 PLoS Med. 2016 PMC5154502 10.1371/journal.pmed.1002197 32 1 0 46 Humans|*Lymphoma, Follicular|*Clonal Evolution|*Disease Progression|Mutations|DNA, Neoplasm|Cell Transformation, Neoplastic|Clone Cells|B-Lymphocytes 52 P2RY8 27899802 Leukemia 2016 PMC5508072 10.1038/leu.2016.365 11 6 0 46 Child|Humans|CRLF2 protein, human|Receptors, Cytokine|*Acute Lymphoblastic Leukemia|Ikaros Transcription Factor|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Receptors, Purinergic P2Y|Relapses|*Genomics|Mutations|Signal Transduction|P2RY8 protein, human 52 P2RY8 27855558 Leuk. Lymphoma 2016 PMC6077981 10.1080/10428194.2016.1219902 3 0 0 46 Humans|Philadelphia|*Acute Lymphoblastic Leukemia|Philadelphia Chromosome|Fusion Proteins, bcr-abl|CRLF2 protein, human|Receptors, Cytokine|*Base Sequence|*Whole Exome Sequencing|*Sequencing, RNA|Gene Fusions|Signal Transduction|PDGFRB|RCSD1 protein, human|Intracellular Signaling Peptides and Proteins 52 PACRG 27810501 Infect. Genet. Evol. 2016 10.1016/j.meegid.2016.10.030 7 0 0 62 *Tuberculosis|Mycobacterium tuberculosis|Polymorphism, Genetic|Genetic Predisposition to Disease|Proteins|Signal Transduction 68 PACRG 27770595 Cytoskeleton (Hoboken) 2016 PMC5567728 10.1002/cm.21340 3 14 0 62 *Dyneins|*Cilia|*Binding Protein|Axonemes|*Microtubule|Flagella|Chlamydomonas reinhardtii|TYRP1 protein, human|*Membrane Glycoproteins|Plant Proteins|*Chromosome Segregation|Mutation 68 PACRG 28965374 Zhonghua Nan Ke Xue 2016 0 0 0 62 Mice|Animals|*Baculovirus|*Sf9 Cells|*Recombinant Proteins|Vector, Genetic|Transfection|Cloning, Molecular|Spodoptera|Cell Line|Gene Expression|Insect|Pacrg protein, mouse|Proteins 68 PACRG 27193298 Mol. Biol. Cell 2016 PMC4927285 10.1091/mbc.E15-07-0490 5 14 1 62 Animals|Caenorhabditis elegans|Cilia|Caenorhabditis elegans Proteins|Microtubule|Longevity|Signal Transduction Pathways 68 PACRG 26929909 Balkan J. Med. Genet. 2016 PMC4768829 10.1515/bjmg-2015-0009 2 2 0 62 Humans|Pregnancy|Female|Chromosome 6, monosomy 6q|*Chromosome Deletion|Comparative Genomic Hybridization|In Situ Hybridization, Fluorescence|*Chromosomes, Human, Pair 6|*Congenital Hydrocephalus|Karyotyping|Trisomy|Abnormalities, Multiple|Karyotype|Phenotype|*Musculoskeletal Abnormalities|Genotype|PSMB1 protein, human|Proteasome Endopeptidase Complex 68 PACRG 26726850 Sci Rep 2016 PMC4698733 10.1038/srep18278 1 3 1 62 Male|*Meiosis|Spermatids|Cell Cycle Proteins|Nuclear Proteins|Phosphoproteins|Spermatocytes|Spermatogenesis|Amino Acid Sequence|Protein Binding|Binding Sites 68 pacs2 27377964 Cell. Signal. 2016 10.1016/j.cellsig.2016.06.024 4 13 0 228 *Endoplasmic Reticulum Stress|*Insulin Resistance|*Hep G2 Cells|*Thioctic Acid|*Mitochondria|Tunicamycin|Signal Transduction|Palmitic Acid|Insulin|Apoptosis|Phosphorylation 38 pacs2 26943323 Cell Death Differ. 2016 PMC5072422 10.1038/cdd.2016.23 9 6 1 228 Animals|Mice|*Nuclear Factor-Kappab|*Ataxia-Telangiectasia|*DNA Damage|bcl-X Protein|Signal Transduction|Apoptosis|I-kappa B Kinase|Ataxia Telangiectasia Mutated Proteins|Cell Survival|Anti-Apoptotic Proteins|Tumor Necrosis Factor-alpha|Cell Line, Tumor|Gene Expression Regulation, Neoplastic 38 PAGE4 27270343 Asian J. Androl. 2016 PMC5000790 10.4103/1008-682X.181818 8 16 1 57 Male|Humans|*Prostate|*Testis|*Prostate Cancer|Antigens, Neoplasm|Protein Conformation|Phosphorylation|kallikrein-related peptidase 3, human|Prostate Specific Antigen|Cell Line, Tumor|PAGE4 protein, human 31 PAGE4 26747525 BMC Genomics 2016 PMC4706689 10.1186/s12864-015-2359-6 20 2 1 57 Humans|IL10 protein, human|*Interleukin-10|*Head and Neck Cancer|*Disease Progression|Carcinoma, Squamous Cell|Prognosis|*Signal Transduction|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Mutations|Integrins 31 PALMD 27642173 Anim. Genet. 2016 10.1111/age.12507 8 0 0 58 Swine|Animals|*Polymorphism, Single Nucleotide|*RNA Editing|*RNA-Seq|*Phenotype|Genotype|Quantitative Trait Loci|Sus scrofa|*Whole Exome Sequencing|Genetic Association Studies|Alleles|*Mutations|Meat|Homozygote|Transcriptomes 20 panx3 27837015 J. Dent. Res. 2016 PMC5384484 10.1177/0022034516678203 3 3 0 117 Animals|Cell Differentiation|Connexins|Osteogenesis|GJA1 protein, human|Cx43|Gap Junction|Chondrocytes|Osteoblasts|Cell Proliferation|Signal Transduction|*Bone|Communications, Cell|Gene Expression Regulation, Developmental 67 PARP12 27791205 Oncotarget 2016 PMC5363581 10.18632/oncotarget.12858 15 23 0 93 Humans|Neoplasm Recurrence, Local|STAT1 protein, human|STAT1 Transcription Factor|Signal Transduction|Upregulation|Phosphorylation|MCF7 Cells|*Cytoplasm|Interferon-gamma|Membrane Proteins|Transcriptional Activation|*Genotoxic Stress 20 PARP12 27234208 Mol. Biochem. Parasitol. 2016 10.1016/j.molbiopara.2016.05.012 0 0 0 93 *Diphtheria Toxin|*Peptide Elongation Factor Tu|*Entamoeba histolytica|*Transferase|Escherichia coli|Tandem Mass Spectrometry|ADP Ribose Transferases|ADP-Ribose|Bacterial Toxins|EEF1A1 protein, human|*Peptide Elongation Factor 1|Peptide Elongation Factor 2|Poly(ADP-ribose) Polymerases|Vibrio cholerae|Protein Biosynthesis|Protein Processing, Post-Translational|Pseudomonas aeruginosa 20 parpbp 27129221 J. Biol. Chem. 2016 PMC4933475 10.1074/jbc.M116.729699 3 77 1 100 SMAD5 protein, human|Smad5 Protein|SMAD4 protein, human|Smad4 Protein|Bone Morphogenetic Protein|*Signal Transduction|*Ribosylations, ADP|SMAD3 protein, human|Smad3 Protein|Smad Proteins|Smad1 Protein|*Gene Expression Regulation|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Transforming Growth Factor beta|Bone Morphogenetic Protein 2|Cell Differentiation|Cell Nucleus 25 parpbp 26941064 Nat Commun 2016 PMC4785230 10.1038/ncomms10881 38 33 2 100 Humans|Mice|Animals|*Telomere|*Activator Protein-1|Telomeric Repeat Binding Protein 2|Telomere-Binding Proteins|DNA Repair|*Homologous Recombination|DNA Damage|DNA|DNA End-Joining Repair|Protein Binding 25 parpbp 26898760 Oncogene 2016 10.1038/onc.2016.3 12 3 1 100 Humans|Neoplasm Recurrence, Local|*Lung Adenocarcinoma|Lung Neoplasms|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|*DNA Repair|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Carcinogenesis|Cell Line, Tumor|Cell Movement|Gene Knockdown|Tumor Microenvironment 25 parpbp 26880244 J. Invest. Dermatol. 2016 10.1016/j.jid.2016.01.031 10 7 0 100 *Cisplatin|Xeroderma Pigmentosum, Complementation Group B|*Xeroderma Pigmentosum|Xeroderma Pigmentosum Group A Protein|DNA Repair|Antineoplastic Agents|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|DNA-Binding Proteins|Endonucleases|DNA Damage|Drug Resistance, Neoplasm|Apoptosis|*Autophagy|Melanoma 25 parpbp 26792895 Nucleic Acids Res. 2016 PMC4838361 10.1093/nar/gkw024 13 31 1 100 Humans|*Proliferating Cell Nuclear Antigen|*DNA Repair|*DNA Replication|*Homologous Recombination|RAD18 protein, human|DNA-Binding Proteins|DNA Damage|Ubiquitin-Protein Ligases|DNA-Directed DNA Polymerase|Ubiquitin|DNA|HeLa Cells|Ultraviolet Rays 25 pax6a 27387288 PLoS ONE 2016 PMC4936704 10.1371/journal.pone.0158210 3 4 1 0 Animals|Hedgehog Proteins|*Zebrafish|*Habenula|*Neurogenesis|Body Patterning|Zebrafish Proteins|Signal Transduction|Diencephalon|Gene Expression Regulation, Developmental|Transcription Factor|NEUROG1 protein, human|Nerve Tissue Proteins|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Embryo, Nonmammalian|Neurons|neurod4 protein, zebrafish 32 PCDH11Y 27617217 Meta Gene 2016 PMC5006134 10.1016/j.mgene.2016.07.004 3 0 1 45 Male|Humans|Female|Adolescent|*Gynecomastia|Chromosome Xq duplication syndrome|Sex Chromosome Disorders|Sex Chromosome Aberrations|Chromosomes, Human, X|Intellectual Disability|Prader-Willi Syndrome|Abnormalities, Multiple|Comparative Genomic Hybridization|Trisomy|Gene Duplication|Phenotype|*Chromosome Structures|In Situ Hybridization, Fluorescence|Seizures 24 PCDH11Y 27058445 Am. J. Hum. Genet. 2016 PMC4833433 10.1016/j.ajhg.2016.02.023 19 0 1 45 Humans|Male|Animals|*Neanderthals|*Chromosomes, Human, Y|Hominids|Chimpanzee|Genetic Variation|Genome, Human|Phylogeny|DNA|Exome|Base Sequence|Polymorphism, Single Nucleotide|Spain|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 24 PCDH11Y 26759715 Biol Sex Differ 2016 PMC4710049 10.1186/s13293-015-0056-4 0 2 1 45 Male|Humans|*Sex Characteristics|Y Chromosome|*Central Nervous System|Cadherins|Brain 24 PCDH8 27875771 Differentiation 2016 10.1016/j.diff.2016.10.002 1 4 0 136 Animals|*Xenopus laevis|*Gastrulation|*Cell Polarity|Xenopus Proteins|*Signal Transduction|Gastrula|NLK protein, human|*Intracellular Signaling Peptides and Proteins|*Protein-Serine-Threonine Kinases|Wnt Proteins|Embryo, Nonmammalian|Cadherins|Morphogenesis|Cell Migration|Papc protein, Xenopus 88 PCDH8 27643535 Pediatr Blood Cancer 2016 10.1002/pbc.26259 4 4 0 136 Humans|Child|*Prognosis|DNA Methylation|Cadherins|Promoter Regions, Genetic|Disease-Free Survival|Biomarkers, Tumor|Neoplasm Recurrence, Local|Polymerase Chain Reaction|*Acute Lymphoblastic Leukemia 88 PCDH8 27246830 Cancer Res. 2016 PMC5033679 10.1158/0008-5472.CAN-15-3073 20 44 0 136 Humans|*Glioma|STAT3 protein, human|*STAT3 Transcription Factor|*Tumorigenesis|miRNA|Genes, Tumor Suppressor|3' Untranslated Region|Brain Neoplasms|Gene Expression Regulation, Neoplastic|*Cell Transformation, Neoplastic|Glioblastoma|Cell Proliferation|Cell Movement|Cell Line, Tumor|Apoptosis|Transfection|PCDH8 protein, human|Cadherins 88 PCDH8 26961748 BMC Med Genomics 2016 PMC4784386 10.1186/s12920-016-0173-x 8 0 1 136 *Parkinson Disease|*Consensus|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Genetic Predisposition to Disease 88 PCNP 27775093 Sci Rep 2016 PMC5075790 10.1038/srep35382 12 5 1 156 endolysin|*Endopeptidases|Gram Negative Bacteria|*Anti-Bacterial Agents|Gram Positive Bacteria|*Streptococcus|Bacteria 59 PCP4 27876793 Nat Commun 2016 PMC5122967 10.1038/ncomms13583 1 23 0 105 *Calmodulin|*Calcium|*Static Electricity|Protein Binding|Protein Structure, Tertiary|Binding Sites|Amino Acid Sequence|Kinetics|Nerve Tissue Proteins|Models, Molecular 109 PCP4 27852047 Oncotarget 2016 PMC5354930 10.18632/oncotarget.13328 11 1 0 105 *Prognosis|*Esophageal Cancer|*Gene Expression Profiling|Carcinoma, Squamous Cell|Adenocarcinoma|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Gene Expression Profiles 109 PDE3B signalling 27720677 Immunol. Lett. 2016 10.1016/j.imlet.2016.09.014 2 2 0 0 *Phosphatidylinositol 3-Kinases|*Phosphoinositide 3 Kinase|*Phagocytosis|*Macrophage|Class Ib Phosphatidylinositol 3-Kinase|Signal Transduction|Cyclic AMP|Cell Line 21 PDE3B signalling 27696085 Purinergic Signal. 2016 PMC5334196 10.1007/s11302-016-9536-1 1 0 0 0 Mice|Animals|*Transcriptome|*Endotoxemias|*Myocardium|Receptor, Adenosine A2A|Mice, Knockout|Adenosine 21 pdia2 27154727 Metab Brain Dis 2016 10.1007/s11011-016-9830-1 7 1 0 61 Male|Rats|Animals|*Dietary Sucrose|Insulin Resistance|Dietary Fats|Metabolic Syndrome|Impaired Glucose Tolerance|*Endoplasmic Reticulum Stress|Triglycerides|Liver|*Precipitating Factors|Gain, Weight|Weaning|Diet|*Hippocampus 23 pdia2 26934777 Indian J. Exp. Biol. 2016 0 0 0 61 Rats|Animals|*Downregulation|*Protein Disulfide-Isomerases|*mRNA|2D Gel Electrophoresis|*Hyperglycemia|Proteomics|Proteins|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Western Blot|Streptozotocine 23 PDLIM1 27651343 Turk Neurosurg 2016 10.5137/1019-5149.JTN.17746-16.1 10 0 0 164 Glioblastoma|Brain Neoplasms|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Cycle|Apoptosis 43 PDLIM1 27310465 Autophagy 2016 PMC5082779 10.1080/15548627.2016.1192750 14 0 1 164 Mice|Humans|Male|Animals|*Spermatids|*Spermiogenesis|*Autophagy|LDB2 protein, human|Transcription Factors|Spermatozoa|Cytoskeleton|LIM Domain Proteins|Testis|Cell Differentiation|Mice, Knockout|Microtubules|Cytoplasm|Sperm Motility 43 PDLIM1 27078885 PLoS ONE 2016 PMC4831832 10.1371/journal.pone.0153574 5 24 1 164 *Friedreich Ataxia|frataxin|Iron-Binding Proteins|*Oxidative Stress|*Biomarkers|mRNA|Histone Deacetylase Inhibitor|Antioxidants|Dimethylfumarate|Signal Transduction|Lymphocytes 43 PDLIM1 27068564 Proteomics Clin Appl 2016 10.1002/prca.201500138 2 0 0 164 Humans|Female|*Autoantibodies|Antigens, Neoplasm|Biomarkers, Tumor|Early Detection of Cancer|Cancer|Enzyme-Linked Immunosorbent Assay|TYMS protein, human|Thymidylate Synthase 43 PDLIM1 26986811 Autophagy 2016 PMC4854559 10.1080/15548627.2016.1159377 14 0 1 164 Male|Mice|Animals|*Sertoli Cells|Seminiferous Tubules|Blood-Testis Barrier|Spermatids|Cytoskeleton|Spermatozoa|Spermatogenesis|*Autophagy|*Cytoplasm|Actin Cytoskeleton|Actins|Microtubules|Cell Differentiation 43 PDLIM1 26863628 Oncotarget 2016 PMC4905491 10.18632/oncotarget.7115 2 0 1 164 Humans|*Glioblastoma|DNA Copy Number Variations|Retrospective Studies|Brain Neoplasms|Magnetic Resonance Imaging|Genomics|Gene Expression Profiling|Genome|Kaplan-Meier Analysis|Gene Expression|Phenotype|Signal Transduction 43 PDZD2 28007035 BMC Med. Genet. 2016 PMC5178083 10.1186/s12881-016-0359-2 1 0 0 125 *Whole Exome Sequencing|Sacral defect and anterior sacral meningocele|*DNA Copy Number Variations|*Abnormalities, Multiple|*Meningocele|*Sacrococcygeal Region|Exome|*Nervous System Malformations|High-Throughput Nucleotide Sequencing|Polymorphism, Single Nucleotide|Mutation 57 PDZD2 26918600 Oncotarget 2016 PMC5421839 10.18632/oncotarget.6917 3 3 1 125 Humans|*Carcinoma, Renal Cell|Genome-Wide Association Study|Kidney Neoplasms|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Alleles|Genotype|Odds Ratio|Case-Control Studies|Risk Factors|African Americans|*Germ Line|PDZD2 protein, human|Neoplasm Proteins|Adaptor Proteins, Signal Transducing|ITPR2 protein, human|Inositol 1,4,5-Trisphosphate Receptors 57 PDZD7 28031293 Hum. Mol. Genet. 2016 PMC6075602 10.1093/hmg/ddw421 9 4 0 36 Mice|Animals|*PDZ Domains|Usher syndrome, type 2A|Usher Syndrome|Usher Syndrome, Type IG|*Hair Cells, Cochlear|Carrier Proteins|Nerve Tissue Proteins|Membrane Proteins|Extracellular Matrix Proteins|Cochlea|Photoreceptor Cells|Retina|PDZD7 protein, mouse|Ush2a protein, mouse 30 PDZD7 27525485 Elife 2016 PMC5005036 10.7554/eLife.18312 11 19 1 36 Mice|Animals|*Stereocilia|Usher Syndrome, Type IC|Usher Syndromes|Hair Cells, Auditory|Myosins|VIIa, Myosin|Carrier Proteins|Ear, Inner|PDZD7 protein, mouse|Ush1c protein, mouse 30 PDZD7 26849169 Ear Hear 2016 10.1097/AUD.0000000000000278 0 0 1 36 Nonsyndromic Deafness|Nonsyndromic sensorineural hearing loss|Usher Syndrome|Pedigree|Genotype-Phenotype Association|Heterozygote|Phenotype|Mutation|Audiometries|Genotype|Carrier Proteins 30 PDZRN3 26934292 Int. J. Dev. Biol. 2016 10.1387/ijdb.150381ld 1 1 0 80 Animals|*Xenopus laevis|Pronephros|*Organogenesis|Xenopus Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Morphogenesis|In Situ Hybridization|Zebrafish|Kidney|Morpholinos|Cell Differentiation|mRNA|PDZRN3 protein, Xenopus laevis|Carrier Proteins 26 PGDF 27619183 Colloids Surf B Biointerfaces 2016 10.1016/j.colsurfb.2016.09.005 1 0 0 0 Mice|Animals|*Hydrogel|*Platelet-Derived Growth Factor BB|*Microspheres|Chitosan|Platelet Derived Growth Factor B|Silk Fibroin|Glycerophosphates|Gelatin|Mice, Inbred BALB C 49 PGDF 26432280 J. Vasc. Surg. 2016 10.1016/j.jvs.2015.07.091 0 0 0 0 Rats|Animals|Tunica Intima|Aorta, Abdominal|Hyperplasia|Muscle, Smooth, Vascular|Platelet-Derived Growth Factor|Polytetrafluoroethylene|Vena Cava, Inferior|3'-(1-butylphosphoryl)adenosine|Rats, Inbred Lew|Culture Media, Conditioned 49 PGDF 26769046 Arterioscler. Thromb. Vasc. Biol. 2016 10.1161/ATVBAHA.115.306302 6 7 0 0 Mice|Animals|*Up-Regulation|BMP4 protein, human|Bone Morphogenetic Protein 4|platelet-derived growth factor A|*Platelet-Derived Growth Factor|Endothelium, Vascular|Vasodilation|Diabetic Angiopathies|TYRP1 protein, human|*Membrane Glycoproteins|SMAD4 protein, human|*Smad4 Protein|Vasodilator Agents|Oxidative Stress|*Transcriptional Activation|Mice, Inbred C57BL|Diabetes Mellitus 49 PHLDB1 27068087 Infect. Immun. 2016 PMC4907137 10.1128/IAI.00142-16 8 0 0 51 Humans|Animals|*Yersinia enterocolitica|*Phosphoinositide 3 Kinase|*Phosphatidylinositol 3-Kinases|Listeria monocytogenes|Adhesins, Bacterial|Bacterial Proteins|MTOR protein, human|TOR Serine-Threonine Kinases|Membrane Proteins|Host-Pathogen Interactions|Actin Cytoskeleton|Signal Transduction|RNA Interference|HeLa Cells|*Hyaluronoglucosaminidase 41 PHLDB1 26839018 J. Neurooncol. 2016 PMC4835517 10.1007/s11060-016-2066-4 4 1 1 51 Humans|*Genes, erbB-1|Genome-Wide Association Study|*Glioma|Brain Neoplasms|RTEL1 protein, human|*DNA Helicases|*Genes, p16|Glioblastoma|Genetic Predisposition to Disease|Genotype|Alleles|Polymorphism, Single Nucleotide|Cyclin-Dependent Kinase Inhibitor p15|Cyclin-Dependent Kinase Inhibitor p16|*Risk Factors|Biomarkers, Tumor|Mutation|*Diploidy 41 PHOX2A 28033651 Dev Neurobiol 2016 10.1002/dneu.22477 3 0 0 119 Humans|Animals|*Axon Guidance|*Axons|Duane Retraction Syndrome|Motor Neurons|Strabismus|*Skull|Cranial Nerves|Oculomotor Muscles|Ocular Motility Disorders|Brainstem|Mutations|Tubulin|Microtubules 188 PHOX2A 27186394 Am J Cancer Res 2016 PMC4859651 25 1 0 119 Mice|Animals|Mice, Nude|*Lung Cancer|*Cell Proliferation|Long Non-Coding RNA|MicroRNAs|Carcinoma, Non-Small-Cell Lung|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Line, Tumor|Downregulation|Cell Movement|3' UTR 188 PHPT1 27034094 Sci Rep 2016 PMC4817053 10.1038/srep23658 7 5 1 62 Animals|Humans|Hydrogen Peroxide|PHPT1 protein, human|*Phosphoric Monoester Hydrolases|*Redox|Protein Conformation|Site, Catalytic|phosphohistidine|Histidine|Models, Molecular|Amino Acid Sequence|Methionine|Reactive Oxygen Species|Post-Translational Modifications|Oxidative Stress 42 PILRA 27981441 J. Neurovirol. 2016 PMC5440480 10.1007/s13365-016-0504-x 7 4 0 23 Animals|Cricetinae|Humans|simplexvirus receptor|*Receptors, Virus|glycoprotein D, Human herpesvirus 1|Viral Envelope Proteins|TNFRSF14 protein, human|Receptors, Tumor Necrosis Factor, Member 14|NECTIN1 protein, human|Nectin-1|glycoprotein B, Simplexvirus|Herpesvirus 1, Human|Herpes Simplex|Herpesvirus 2, Human|Virus Internalization|Cell Adhesion Molecules|Membrane Fusion|CHO Cells|Herpesviridae Infections|ACKR1 protein, human 38 PILRA 27803463 Biol. Pharm. Bull. 2016 10.1248/bpb.b16-00533 1 0 0 23 38 PILRA 27029068 Oncotarget 2016 PMC5173034 10.18632/oncotarget.8397 1 27 1 23 Humans|Female|*Natural Killer Cells|Receptors, Natural Killer Cell|Cytotoxicity, Immunologic|CD56 Antigen|Receptors, Immunologic|Lymphocyte Activation|Membrane Glycoproteins|Lectins, C-Type|Antigens, CD|Ligands 38 PILRA 26840635 Eur. J. Immunol. 2016 10.1002/eji.201545897 5 0 1 23 Mice|Animals|*Monocytes|*Obesity|Macrophages|Inflammation|Insulin Resistance|Receptors, Immunologic|Adipose Tissue|Liver|Fibrosis, Liver 38 PIWIL3 27858163 J. Cancer Res. Clin. Oncol. 2016 10.1007/s00432-016-2305-2 4 0 0 21 Melanoma, Cutaneous Malignant|*Melanomas|Skin Neoplasms|Sentinel Lymph Node Biopsy|Lymphatic Metastasis|Prognosis|Immunohistochemistry|Lymph Nodes|Disease-Free Survival|Biomarkers, Tumor|*Neoplasms, Second Primary 24 PIWIL3 27177224 Oncotarget 2016 PMC5122362 10.18632/oncotarget.9272 24 2 2 21 *Piwi-Interacting RNA|*Prognosis|Argonaute Proteins|Epigenesis, Genetic|Cell Line, Tumor|Epigenetic|Gene Expression Regulation|mRNA|Germ Line 24 PIWIL3 27434648 PLoS ONE 2016 PMC4951028 10.1371/journal.pone.0159507 2 2 1 21 Humans|Pregnancy|Female|*DNA Methylation|*Blastocysts|*Embryo Implantation|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|Epigenesis, Genetic|Embryonic Development|*Monosomy|DNA Modification Methylases|Aneuploidy|Chromatin Assembly and Disassembly|PARVB protein, human|Actinin|CYFIP1 protein, human|Adaptor Proteins, Signal Transducing|PRMT5 protein, human|Protein-Arginine N-Methyltransferases|ADM2 protein, human 24 PIWIL3 27215607 Mol. Cell Proteomics 2016 PMC4974340 10.1074/mcp.M115.056887 33 0 0 21 Humans|*Proteomics|*Oocytes|Oogenesis|Proteome|Metaphase|Cell Nucleus 24 PIWIL3 26811690 Onco Targets Ther 2016 PMC4712976 10.2147/OTT.S91295 10 1 1 21 Humans|Male|*Carcinoma, Renal Cell|Argonaute Proteins|Piwi-Interacting RNA|Testis|Germ-Line Cells|Transposable Elements|Kidney Neoplasms|PIWIL1 protein, human|PIWIL2 protein, human|PIWIL4 protein, human 24 pkd1l1 27616478 Am. J. Hum. Genet. 2016 PMC5065643 10.1016/j.ajhg.2016.07.011 11 0 0 17 Child|Humans|Mice|Animals|Situs Inversus|*Mutations|Dextrocardia|Situs Ambiguus|*Alleles|Pedigree|Homozygote|Phenotype|Sequencing, Whole Exome|Genes, Regulator|Missense Mutation|PKD1L1 protein, human|Membrane Proteins 20 pkd1l1 27348301 Elife 2016 PMC4922860 10.7554/eLife.13413 17 11 1 17 Humans|*Calcium|*TRPP Cation Channels|EF Hand|Calcium Channels|*Ion Transport|*Calcium, Dietary|*Signal Transduction|Models, Molecular|Cilium 20 pkd1l1 27272319 PLoS Genet. 2016 PMC4894641 10.1371/journal.pgen.1006070 14 12 1 17 Mice|Animals|*Cilia|*TRPP Cation Channels|Body Patterning|Nodal Protein|Lateral Plate Mesoderm|*Signal Transduction|Embryo, Mammalian|Gene Expression Regulation, Developmental|*Genetic Testing|Transforming Growth Factor beta|Transcription Factors 20 Pl15 27837974 J. Dairy Sci. 2016 10.3168/jds.2016-11479 4 0 0 0 23 Pl15 27179857 J. Dairy Sci. 2016 10.3168/jds.2015-10445 0 0 0 0 23 Pl15 26931652 Methods 2016 PMC4854231 10.1016/j.ymeth.2016.02.017 34 0 2 0 *Cryoelectron Microscopy|Macromolecular Complexes|Transmission Electron Microscopy|Crystallography, X-Ray|Image Processing, Computer-Assisted|Imaging, Three-Dimensional|*Molecular Biology|Proteins|Software|Specimen Handling|Negative Staining|*Diagnostic Tests, Routine 23 PLCL1 27491861 Mol Oncol 2016 PMC5423197 10.1016/j.molonc.2016.07.004 6 0 0 51 40 PLCL1 27167772 Endocrinology 2016 PMC4972893 10.1210/en.2015-1914 6 27 1 51 40 PLCL1 27028907 J. Intern. Med. 2016 PMC4914449 10.1111/joim.12444 22 7 1 51 40 PLCL1 26879886 Clin. Genet. 2016 10.1111/cge.12761 9 0 0 51 40 PLXDC2 27863428 Oncotarget 2016 PMC5356749 10.18632/oncotarget.13399 3 2 0 107 29 PLXDC2 27170308 Mol. Cancer Res. 2016 10.1158/1541-7786.MCR-15-0366 4 0 0 107 29 PM20D1 27378359 Rejuvenation Res 2016 10.1089/rej.2016.1859 1 2 0 15 Mice|Animals|Uncoupling Protein 1|*Mitochondria|Adaptive Thermogenesis|Adipose Tissue, Brown|Energy Expenditure|Inner Mitochondrial Membrane|Oxidative Phosphorylation|Mitochondrial Proteins|Adipocytes|Obesity|Metabolic Pathway|*Respiration|PM20D1 protein, mouse|Amidohydrolases 27 PM20D1 27374330 Cell 2016 PMC4947008 10.1016/j.cell.2016.05.071 53 8 0 15 Mice|Animals|Uncoupling Protein 1|*Mitochondria|Thermogenesis|Adipose Tissue, Brown|Mitochondrial Proteins|Cell Respiration|Energy Expenditure|Adipocytes|*Amino Acids|Ion Channels|Acids, Fatty|Homeostasis|*Biological Transport|PM20D1 protein, mouse|Amidohydrolases 27 POTEE 28018022 Dis. Markers 2016 PMC5149637 10.1155/2016/5179594 2 10 0 39 Humans|*Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|*Upregulation|TYRP1 protein, human|*Membrane Glycoproteins|Carcinoma|Gene Expression Regulation, Neoplastic|*Ribosomes|Cell Line, Tumor|*Transcriptional Activation|Ribosomal Protein|DNA Methylation|Promoter Regions, Genetic|Cell Proliferation 20 POTEE 27725671 Nat Commun 2016 PMC5062574 10.1038/ncomms12522 35 0 1 39 Humans|*Diaspora|African Continental Ancestry Group|Gene Flow|Genetics, Population|European Continental Ancestry Group|Haplotypes|Genome, Human|Hispanic Americans|Polymorphism, Single Nucleotide|Ethnic Groups|Geography|West Indies|Caribbean 20 POTEE 27725664 Nat Commun 2016 PMC5062569 10.1038/ncomms12521 20 0 1 39 Humans|United States|*Genomics|*Personalized Medicine|African Continental Ancestry Group|Genome, Human|Genetic Variation|European Continental Ancestry Group|SNPs 20 POU3F1 28032857 Cell Death Dis 2016 PMC5261017 10.1038/cddis.2016.420 9 12 0 285 Humans|Male|*Heme Oxygenase-1|*Pseudopodia|*Prostate Cancer|Cell Adhesion|Cell Line, Tumor|Cell Proliferation|Down-Regulation|Cell Communication|Co-culture|Cytoskeleton 138 POU3F1 27294512 Nat. Neurosci. 2016 PMC4964942 10.1038/nn.4321 31 22 1 285 Mice|Animals|Schwann Cells|Peripheral Nerve Injury|Nerve Regeneration|Myelin Sheath|*Neurogenesis|Sciatic Nerve|Transcription Factors|SOXE Transcription Factors|Early Growth Response Protein 2|Axons|SOX2 protein, human|SOXB1 Transcription Factors|Cell Differentiation|ZEB2 protein, mouse|Zinc Finger E-box Binding Homeobox 2 138 POU3F1 27279156 Dev. Growth Differ. 2016 10.1111/dgd.12295 3 3 0 285 *Neural Plate|SOX2 protein, human|Transcription Factor, SOX-2|Mesoderm, Paraxial|Epiblast|Somites|Lineages, Cell|Stem Cells|Embryonic Development|Gene Expression Regulation, Developmental|Brachyury protein|T-Box Domain Proteins|Fetal Proteins 138 POU6F1 27521061 Gene Expr. Patterns 2016 10.1016/j.gep.2016.08.001 0 0 0 30 Mice|Animals|*Genes, Homeobox|*Vomeronasal Organ|In Situ Hybridization, Fluorescence|*Mice, Inbred C57BL|proto-oncogene protein Pbx3|Proteins, Homeo Domain|LIM-Homeodomain Proteins|Transcription Factors|Cell Differentiation|Olfactory Mucosa|Repressor Proteins|Gene Expression Regulation, Developmental|Olfactory Bulb|Stem Cells|Myeloid Ecotropic Viral Integration Site 1 Protein|Neurons|Zfhx3 protein, mouse|Lhx2 protein, mouse 34 POU6F1 27009109 Reprod. Biol. Endocrinol. 2016 PMC4806453 10.1186/s12958-016-0149-x 1 1 1 30 Humans|Mice|Animals|*Assisted Reproductive Technology|Embryo Culture Techniques|*Embryo, Mammalian|Blastocyst|Embryonic Development|*Bioassay 34 PPP1R3A 27587435 Clin. Cancer Res. 2016 10.1158/1078-0432.CCR-16-0967 3 0 0 909 40 PPP1R3A 26830856 Diabetes Res. Clin. Pract. 2016 10.1016/j.diabres.2015.12.015 4 0 0 909 Humans|*DNA Copy Number Variations|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome, Human|Genotype|Phenotype 40 PRDM8 27698795 Oncol Lett 2016 PMC5038494 10.3892/ol.2016.5029 8 3 1 41 *Pituitary Neoplasms|*Whole Exome Sequencing|Neoplasm Recurrence, Local|Adenoma|PRDM2 protein, human|DNA-Binding Proteins|Transcription Factors|Nuclear Proteins|Histone-Lysine N-Methyltransferase|Exomes|F-actin-binding proteins|Carrier Proteins|Gene Expression Regulation, Neoplastic|Microfilament Proteins|Cell Transformation, Neoplastic 25 PRDM8 27278638 Mol Med Rep 2016 10.3892/mmr.2016.5375 1 1 0 41 Humans|*Promoter Regions, Genetic|CpG Islands|DNA Methylation|Epigenesis, Genetic|hydrogen sulfite|Sulfites|Phenotypes|Down Syndrome|PRDM8 protein, human|Carrier Proteins|Nuclear Proteins 25 PRDM8 26909595 Oncotarget 2016 PMC4905437 10.18632/oncotarget.7458 3 2 1 41 Humans|*Dyskeratosis Congenita|*B-DNA|*DNA Methylation|Anaemia, Aplastic|Hemoglobinuria, Paroxysmal|Bone Marrow Diseases|Bone Marrow Failure Syndromes|Telomere|Mutation|PRDM8 protein, human|Carrier Proteins|Nuclear Proteins 25 PRICKLE2 27759658 Medicine (Baltimore) 2016 PMC5079342 10.1097/MD.0000000000005209 1 3 1 83 Humans|telomerase RNA|*Telomerase|*Quantitative Trait Loci|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|Cancer|Genotype|RNA 50 PRICKLE2 27155041 Mech. Dev. 2016 10.1016/j.mod.2016.05.002 11 0 0 83 Humans|Female|Mice|Animals|*Cell Polarity|Drosophila melanogaster|*Oviduct|Membrane Proteins|Nerve Tissue Proteins|Carrier Proteins|Intracellular Signaling Peptides and Proteins|*Epithelium|*Fallopian Tubes|Mice, Transgenic|Signal Transduction|Morphogenesis|Vertebrates|VANGL2 protein, human|VANGL1 protein, human|Vangl1 protein, mouse|Prickle2 protein, mouse|LIM Domain Proteins 50 PRICKLE2 26904945 Cell Rep 2016 PMC4775428 10.1016/j.celrep.2016.01.069 24 9 0 83 Animals|*Cilia|Xenopus laevis|Cell Polarity|Zebrafish|Xenopus Proteins|Zebrafish Proteins|Microtubule|*Cell Movement|Embryo, Nonmammalian|Dyneins|Membrane Proteins|Gene Expression Regulation, Developmental|Signal Transduction 50 PRIMA1 27533450 Oncotarget 2016 PMC5308692 10.18632/oncotarget.11241 11 24 0 187 Humans|*Multiple Myeloma|2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one|*Proteostasis|*Endoplasmic Reticulum Stress|*Bridged Bicyclo Compounds, Heterocyclic|*Aza Compounds|p73 protein, human|*Tumor Protein p73|Bortezomib|Activating Transcription Factor 6|X-Box Binding Protein 1|Endoribonucleases|TP53 protein, human|Tumor Suppressor Protein p53|Apoptosis|Protein-Serine-Threonine Kinases|Endoplasmic Reticulum|Cell Line, Tumor 67 PRIMA1 27523638 Toxicol. Appl. Pharmacol. 2016 10.1016/j.taap.2016.08.009 0 1 0 187 Pregnancy|Male|Female|Animals|Rats|*Cuprizone|*Myelin Sheath|*Transcriptome|*Neuroglia|*Neurons|Neurogenesis|*Brain|Synaptic Transmission|Hippocampus|Gene Expression Profiling|Cerebral Cortex|Prenatal Exposure Delayed Effects 67 PRIMA1 27356594 Ceska Slov Farm 2016 0 0 0 187 Animals|Mice|Butyrylcholinesterase|Acetylcholinesterase|Nerve Tissue Proteins|Membrane Proteins|Muscle Proteins|Exon|Muscles|Collagen|Acetylcholine|Mutation 67 PRIMA1 26742039 Int J Mol Sci 2016 PMC4730312 10.3390/ijms17010067 6 9 1 187 Humans|Female|*DNA Methylation|*Borderline Personality Disorder|Epigenesis, Genetic|*rDNA|CpG Islands|Promoter Regions, Genetic|Diagnostic and Statistical Manual of Mental Disorders|PRIMA1 protein, human|Membrane Proteins|Nerve Tissue Proteins 67 PRSS56 27440996 Mol. Vis. 2016 PMC4945165 4 1 0 17 Hyperopia|Genome-Wide Association Study|Genetic Predisposition to Disease|Myopia|Genetic Association Studies|Polymorphism, Single Nucleotide|Refractive Errors|Ocular Refraction 26 prune2 27641066 J. Cell. Mol. Med. 2016 PMC5264145 10.1111/jcmm.12960 0 12 0 110 *Glioblastoma|Brain Neoplasms|*Tumorigenesis|*Cell Transformation, Neoplastic|Cell Proliferation|Neoplasm Invasiveness|Cancer Stem Cells|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Differentiation|RNA Interference|NK Cells 34 prune2 27453342 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.07.089 1 4 0 110 Humans|Transcription Factor E2F1|Neuroblastoma|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|*Genes, Regulator|Downregulation|Promoter Regions, Genetic|Binding Site|RNA, Messenger|E2F1 protein, human 34 prune2 27001435 J. Endocrinol. Invest. 2016 10.1007/s40618-016-0447-3 11 0 0 110 Humans|*Parathyroid Neoplasms|Hyperparathyroidism, Primary|Germ-Line Mutation|Tumor Suppressor Proteins|Hypercalcemia|Mutation 34 PTAFR 27462464 Cell Discov 2016 PMC4941644 10.1038/celldisc.2016.17 9 26 1 671 39 PTAFR 27000824 Med. Oncol. 2016 10.1007/s12032-016-0751-y 1 0 0 671 39 PTAFR 26756918 Environ. Health Perspect. 2016 PMC4937856 10.1289/ehp.1509834 28 1 1 671 39 PTAFR 26720402 PLoS ONE 2016 PMC4697844 10.1371/journal.pone.0145691 3 38 1 671 Humans|Mice|Animals|*Hedgehog Proteins|Smoothened Receptor|Zinc Finger Protein GLI1|*Signal Transduction|platelet activating factor receptor|Receptors, G-Protein-Coupled|Kruppel-Like Transcription Factors|*Kidney|Platelet Membrane Glycoproteins|Fibrosis|Transcription Factor|Ethanol|Collagen Type I 39 PTBP2 27940503 RNA 2016 PMC5311500 10.1261/rna.058040.116 14 1 0 322 *RNA|*Endoplasmic Reticulum Stress|Unfolded Protein Response|eIF-2 Kinase|*Nonsense Mediated mRNA Decay|Endoplasmic Reticulum|Thapsigargin|Signal Transduction|Alternative Splicing|Membrane Proteins|DNA-Binding Proteins 77 PTOV1 28029646 Oncotarget 2016 PMC5355357 10.18632/oncotarget.14104 1 45 0 127 Humans|Male|*Prostate Cancer|Neoplasm Proteins|Neoplasm Grading|Biomarkers, Tumor|*Neoplastic Processes|Cell Line, Tumor|Urologic Neoplasms|Oncogenesis|Disease Progression|PTOV1 protein, human 38 PTOV1 27804940 Arkh. Patol. 2016 10.17116/patol20167859-14 0 0 0 127 Humans|Male|Prostatic Intraepithelial Neoplasia|*Prostatic Neoplasms|Prostatectomy|Adenocarcinoma|Biomarkers, Tumor|Racemases and Epimerases|Neoplasm Proteins|Biopsy|Immunoenzyme Techniques|PTOV1 protein, human 38 PTOV1 27060981 J. Pathol. 2016 10.1002/path.4725 8 8 0 127 Male|Humans|Neoplasm Recurrence, Local|Cancer Stem Cells|Wnt Signaling Pathway|*Prostatic Neoplasms|beta Catenin|Gene Expression Regulation, Neoplastic|*Catenins|Cell Line, Tumor|Cell Proliferation|Xenograft Model Antitumor Assays|Apoptosis|Great Britain|Ireland|PTOV1 protein, human|Neoplasm Proteins|Biomarkers, Tumor 38 PTOV1 26992242 Oncotarget 2016 PMC5077983 10.18632/oncotarget.8103 5 8 1 127 Male|Humans|*Human Papilloma Virus|*Papillomavirus Infections|*Squamous Cell Carcinoma of Head and Neck|*Laryngeal Neoplasms|Head and Neck Neoplasms|Human Papillomavirus DNA Tests|Cyclin-Dependent Kinase Inhibitor p16|Immunohistochemistry|Carcinoma, Squamous Cell|Oncogene Proteins, Viral|In Situ Hybridization|DNA, Viral|Biomarkers, Tumor|Prognosis|Kaplan-Meier Estimate|mRNA|Disease-Free Survival|*Prostate Cancer 38 PTOV1 26746655 J. Cancer Res. Clin. Oncol. 2016 10.1007/s00432-015-2107-y 4 0 0 127 Humans|Male|*Carcinoma, Transitional Cell|*Urologic Neoplasms|*Prostatic Neoplasms|Urothelium|Neoplasm Proteins|Biomarkers, Tumor|Disease Progression|PTOV1 protein, human 38 PTPRCAP 27538750 Eur. J. Immunol. 2016 10.1002/eji.201646419 1 0 0 34 Mice|Animals|*Precursor Cells, B-Lymphoid|*DNA, Complementary|*Transforming Genes|B Cells|Lymphoma, B-Cell|Proto-Oncogene Proteins c-myc|Cell Transformation, Neoplastic|Retroviridae|*cDNA Libraries|Cell Line|Genetic Vectors 48 PTPRCAP 27332624 2016 PMC5132022 10.1002/art.39792 8 3 1 34 *Salivary Gland Inflammation|Salivary Glands, Minor|Sjogren's Syndrome|Epigenesis, Genetic|*Epigenetic 48 PTPRE 27907186 PLoS ONE 2016 PMC5132173 10.1371/journal.pone.0167519 8 8 0 152 Humans|Diabetes Mellitus, Type 2|*Obesity|*Networks, Gene|Insulin Resistance|*Gene Expression 70 PTPRE 27458171 Oncotarget 2016 PMC5392279 10.18632/oncotarget.10775 22 59 0 152 Humans|Male|Mice|Animals|*Cell Survival|capsazepine|*Capsaicin|STAT3 protein, human|STAT3 Transcription Factor|*Signal Transduction|Jak1 Kinase|Apoptosis|Janus Kinase 2|Cell Proliferation|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Cell Line, Tumor|Antineoplastic Agents|*Prostate Cancer|Phosphorylation|siRNA|Xenograft Model Antitumor Assays|Protein Tyrosine Phosphatase 70 PTPRE 27301828 Sci Rep 2016 PMC4908391 10.1038/srep27891 2 13 1 152 Humans|*Proto-Oncogene Proteins p21(ras)|Proteomics|*Lung Adenocarcinomas|Adenocarcinoma|Lung Neoplasms|ErbB Receptors|Mutations|Receptor Protein-Tyrosine Kinases|*Upregulation|*Transcriptional Activation|Signal Transduction|KRAS protein, human 70 PTPRE 27171439 PLoS ONE 2016 PMC4865206 10.1371/journal.pone.0155660 22 29 1 152 Humans|*Acyl Coenzyme A|*Synthetase|long-chain-fatty-acid-CoA ligase|Coenzyme A Ligases|ACSL6 protein, human|*Gene Expression Regulation|MCF-7 Cells|Lipid Metabolism|Transcriptional Activation|TRIP13 protein, human|ATPases Associated with Diverse Cellular Activities|Cell Cycle Proteins|TAPBPL protein, human|Immunoglobulins|Membrane Proteins 70 PTPRE 27035928 Int. J. Mol. Med. 2016 10.3892/ijmm.2016.2534 10 0 0 152 Humans|*Thyroid Cancers|Thyroid Nodules|Biopsy, Fine-Needle|Thyroid Gland|Cytodiagnosis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Genes, Regulator|RNA, Messenger|Diagnosis, Differential|Gene Expression|Genes, cdc|*Biomarkers|MATN2 protein, human|Matrilin Proteins 70 PTPRM 27784745 Cancer Res. 2016 PMC5215102 10.1158/0008-5472.CAN-16-1386 6 1 0 98 Adult|Humans|Middle Aged|Chromosome 7, monosomy|*Chromosomes, Human, Pair 7|*Leukemia, Myeloid, Acute|*Chromosome Deletion|*Mutations|Monosomy|Sequencing, Next-Generation|Transcription Factors|Kaplan-Meier Estimate|Disease-Free Survival|Phenotype|miRNAs|Biomarkers, Tumor|*Gene Expression 52 PTPRM 27586084 Acta Neuropathol Commun 2016 PMC5009684 10.1186/s40478-016-0372-x 4 7 1 98 Humans|*mRNA|*Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Glioblastoma|PTEN protein, human|PTEN Phosphohydrolase|*Disease Progression|Neoplasm Grading|Gene Expression Regulation, Neoplastic|*Tyrosine Phosphatases, Protein|TYRP1 protein, human|*Membrane Glycoproteins|Mutation|Kaplan-Meier Estimate|Signal Transduction|DUSP26 protein, human|Dual-Specificity Phosphatases 52 PTPRM 27301828 Sci Rep 2016 PMC4908391 10.1038/srep27891 2 13 1 98 Humans|*Proto-Oncogene Proteins p21(ras)|Proteomics|*Lung Adenocarcinomas|Adenocarcinoma|Lung Neoplasms|ErbB Receptors|Mutations|Receptor Protein-Tyrosine Kinases|*Upregulation|*Transcriptional Activation|Signal Transduction|KRAS protein, human 52 PTPRM 27088321 AIDS 2016 PMC4925250 10.1097/QAD.0000000000001124 7 1 0 98 Humans|*Kynurenine|*Tryptophan|Genome-Wide Association Study|*HIV Infections|CD4 Lymphocyte Count|Anti-HIV Agents|Indoleamine-Pyrrole 2,3,-Dioxygenase|*Diagnostic Tests, Routine|Plasma|*African Continental Ancestry Group 52 PURG 27734680 J Phys Chem B 2016 10.1021/acs.jpcb.6b09011 3 0 0 44 *Noradrenaline|monoamine oxidase A, human|*Monoamine Oxidase A|*Catalysis|Quantum Theory|Models, Molecular|Dopamine|Kinetics|Catalytic Domain|Biocatalysis|Flavin-Adenine Dinucleotide|Serotonin|Flavins 36 PURG 27698033 Philos Trans A Math Phys Eng Sci 2016 PMC5052733 10.1098/rsta.2016.0150 3 1 1 44 *Methyl Parathion|phosphorylphosphatase|Phosphoric Monoester Hydrolases|*Hydrolases|Organophosphates|Hydrolysis|Substrate Specificity|Active Site|Paraoxonase|Static Electricity 36 PURG 27331303 Arh Hig Rada Toksikol 2016 10.1515/aiht-2016-67-2802 0 0 0 44 Humans|Female|Young Adult|Adult|*Quetiapine Fumarate|*Fat Emulsions, Intravenous|*Citalopram|Dibenzothiazepines|Antipsychotic Agents|Antidepressive Agents, Second-Generation|Drug Overdose|Suicide, Attempted|Seizures|*Psychotropic Drugs 36 PURG 27312915 Ther Apher Dial 2016 10.1111/1744-9987.12437 0 0 0 44 Humans|*Ankle Brachial Index|*Renal Dialysis|Kidney Failure, Chronic|Risk Factors|Proportional Hazards Models|Cardiovascular Diseases|Survival Analysis|Hypertension|Risk Assessment|Predictive Value of Tests|Triglycerides|Smoking 36 PURG 27121693 Phys Chem Chem Phys 2016 10.1039/c6cp00098c 2 2 0 44 *Monoamine Oxidase A|*Point Mutation|*Catalysis|*Phenethylamines|Kinetics|Active Site|*Oxidation-Reduction|Biocatalysis|Models, Molecular|Flavins|Hydrogen|Mutation 36 PURG 26964227 Guang Pu Xue Yu Guang Pu Fen Xi 2016 0 0 0 44 *Waste Water|*Herbicides|Atrazine|Solid Phase Microextraction|Gas Chromatography Mass Spectrometry|Water Pollutants, Chemical|Solid Phase Extraction|Volatile Organic Compounds|Fluorescence Spectroscopy|acetochlor|Toluidines 36 RAD54B 27902462 Oncotarget 2016 PMC5349998 10.18632/oncotarget.13654 2 16 0 120 *Superoxide Dismutase-1|talazoparib|Phthalazines|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|olaparib|RAD54B protein, human|*DNA Helicases|*Colorectal Cancer|*Nuclear Proteins|DNA Breaks, Double-Stranded|Piperazines|Poly(ADP-ribose) Polymerase Inhibitors|Synthetic Lethal Mutations|Cell Line, Tumor|*Colonic Neoplasms|Apoptosis 67 RAD54B 27655641 Oncotarget 2016 PMC5342006 10.18632/oncotarget.12046 0 9 0 120 Humans|*Lung Adenocarcinoma|Lung Cancer|Adenocarcinoma|Prognosis|RAD54B protein, human|Nuclear Proteins|Biomarkers, Tumor|DNA Helicases|Gene Expression Regulation, Neoplastic|Mutation|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Gene Expression Profiling 67 RAP1GDS1 27760305 J. Mol. Biol. 2016 PMC5153279 10.1016/j.jmb.2016.10.016 10 81 0 152 *Phosphorylation|RAP1A protein, human|*rap1 GTP-Binding Proteins|*Prenylation|rap GTP-Binding Proteins|Guanine Nucleotide Exchange Factors|Cell Adhesion|Monomeric GTP-Binding Proteins|Protein Binding|Isoforms|Amino Acid Sequence 48 RAP1GDS1 27716788 PLoS Genet. 2016 PMC5065127 10.1371/journal.pgen.1006359 8 20 1 152 Animals|*Mitochondrial Dynamics|Mitochondria|Drosophila Proteins|Drosophila melanogaster|Mitochondrial Proteins|rho GTP-Binding Proteins|Parkinson Disease|Drosophila|Protein-Serine-Threonine Kinases|vimar protein, Drosophila|Armadillo Domain Proteins|Miro protein, Drosophila 48 RAP1GDS1 27527066 Sci Rep 2016 PMC4985623 10.1038/srep31431 8 19 1 152 Mice|Animals|*Retinal Degeneration|Chromatography, Liquid|Tandem Mass Spectrometry|MIRN92 microRNA, human|*RNA, Micro|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|mRNA|Downregulation|*Disease Models, Animal|Retina|Up-Regulation|Signal Transduction|Apoptosis|*Biological Phenomena 48 RAP1GDS1 27499730 Front Neurosci 2016 PMC4956656 10.3389/fnins.2016.00340 3 1 1 152 *Tourette Syndrome|*Attention Deficit Disorder with Hyperactivity|Genome-Wide Association Study|Vocal Tics|Obsessive-Compulsive Disorder|Comorbidity|Linkage Disequilibrium|SNPs|Phenotypes 48 RAP1GDS1 26814130 J. Biol. Chem. 2016 PMC4813585 10.1074/jbc.M115.696831 8 6 0 152 Humans|*Guanine Nucleotide Exchange Factor|*Small GTPases|HEK293 Cells|RHOA protein, human|rhoA GTP-Binding Protein|RASGRF1 protein, human|*ras-GRF1|*Oncogenes|RAP1A protein, human|rap1 GTP-Binding Proteins|Protein Prenylation|*Oncogenesis|Protein Binding|DIRAS3 protein, human|rho GTP-Binding Proteins|DIRAS1 protein, human|GTP Phosphohydrolases|Tumor Suppressor Proteins 48 RAPGEF6 27390776 eNeuro 2016 PMC4917737 10.1523/ENEURO.0142-16.2016 7 7 1 96 Mice|Animals|*Guanine Nucleotide Exchange Factors|*Adherens Junctions|*Neurogenesis|Neurons|Cerebral Cortex|Radial Glial Cells|Subcortical Band Heterotopia|Cell Movement|Cell Differentiation|Monomeric GTP-Binding Proteins|Rapgef6 protein, mouse 25 RASGEF1B 27604828 Am. J. Med. Genet. A 2016 10.1002/ajmg.a.37965 3 1 0 25 Humans|Chromosome 4q- Syndrome|Chromosome Deletion|Chromosome Disorders|Intellectual Disability|Comparative Genomic Hybridization|Hypotonia|Phenotype|Speech Disorders|In Situ Hybridization, Fluorescence|Syndrome|*Chromosome Structures|Chromosomes, Human, Pair 4 28 RASGEF1B 27362560 RNA Biol 2016 PMC5014010 10.1080/15476286.2016.1207036 39 0 0 25 Humans|ICAM1 protein, human|*Intercellular Adhesion Molecule-1|*Toll-Like Receptor 4|*Lipopolysaccharides|*RNA, Circular|NF-kappa B|Myeloid Differentiation Factor 88|RNA|Signal Transduction|Macrophages|Cytokines|TLR4 protein, human|RasGEF1B protein, human|ras Guanine Nucleotide Exchange Factors 28 RASGEF1B 27288323 Am. J. Med. Genet. A 2016 10.1002/ajmg.a.37754 2 0 0 25 Child|Humans|Female|Child, Preschool|Comparative Genomic Hybridization|DNA Copy Number Variations|*Speech|*Colon, Sigmoid|Chromosome 4q- Syndrome|Chromosome Deletion|Chromosome Disorders|Intellectual Disability|Developmental Disabilities|Phenotype|Hypotonia, Neonatal|Language Development Disorders|Syndromes|*Chromosome Structures|Chromosomes, Human, Pair 4|Hemangioma 28 RAX2 27838261 Mech. Dev. 2016 10.1016/j.mod.2016.11.002 5 0 0 14 Pregnancy|Animals|Female|*Transcription Factors|Phylogeny|*Vertebrates|Synteny|Gene Duplication|Evolution, Molecular|Genome|Invertebrates|Homeodomain Proteins|Multigene Family|Conserved Sequence|Fishes|Amino Acid Sequence|Jaw|Gene Expression Regulation 25 RBM24 27801482 Genet. Mol. Biol. 2016 PMC5127148 10.1590/1678-4685-GMB-2015-0295 1 12 0 140 Pregnancy|Female|Swine|Animals|Muscle Development|Oligonucleotide Array Sequence Analysis|Sus scrofa|Breeding|Gene Expression Profiling|Muscle, Skeletal|Gene Expression Regulation, Developmental 41 RBM24 27584791 Cell Death Dis 2016 PMC5059856 10.1038/cddis.2016.252 21 27 1 140 Humans|Mice|Animals|*Nasopharyngeal Carcinoma|*Upregulation|lncRNA|Nasopharyngeal Neoplasms|Downregulation|Cell Movement|Gene Expression Regulation, Neoplastic|MicroRNAs|Neoplasm Invasiveness|Cellular Proliferation|Carcinoma|Epithelial-Mesenchymal Transition|Cell Line, Tumor|*Neoplastic Processes|3' Untranslated Regions|*Transcriptional Activation|Gene Knockdown Techniques|Oncogenesis 41 RBM24 27565737 Biochim. Biophys. Acta 2016 10.1016/j.bbadis.2016.08.017 3 5 0 140 *Hirschsprung Disease|mRNA|Neural Crest|MicroRNAs|Cell Proliferation|Ribonuclease III|Cell Movement 41 RC3H1 28011265 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.12.099 0 1 0 430 Mice|Animals|*Intestine, Small|*Lymphocytes|Intestinal Mucosa|Crohn Disease|Interferon-gamma|Inflammation|Tumor Necrosis Factor-alpha|Klrg1 protein, mouse|Receptors, Immunologic 71 REG1B 28009527 Endocrinology 2016 10.1210/en.2016-1551 5 0 0 24 Humans|Mice|Animals|Infant|*Diet, High-Fat|Acute Disease|Pancreatitis|*Islet Cell|*Obesity|Insulin-Secreting Cells|Glucose Intolerance|Streptozotocin Diabetes|Insulin|Blood Glucose|Pancreatitis-Associated Proteins|Cerulein|Homeostasis|*Aging 36 REG1B 27788482 Oncotarget 2016 PMC5363625 10.18632/oncotarget.12834 11 7 0 24 Humans|Mice|Animals|*Prognosis|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|*Metaplasia|Pancreas|Carcinoma in Situ|Adenocarcinoma|Immunohistochemistry|Biomarkers, Tumor|TYRP1 protein, human|*Membrane Glycoproteins|Intrahepatic Cholangiocarcinoma|Liver Neoplasms|Survival Rate|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|REG1A protein, human 36 REG1B 27539087 Diagn Pathol 2016 PMC4989335 10.1186/s13000-016-0526-y 4 0 1 24 Humans|*Squamous Cell Carcinoma of Head and Neck|*Prognosis|Head and Neck Cancer|Carcinoma, Squamous Cell|Kaplan-Meier Estimate|Immunohistochemistry|Disease-Free Survival|Proportional Hazards Models|Biomarkers, Tumor|Chi-Square Distribution|Risk Factors 36 REG1B 26870801 EBioMedicine 2016 PMC4740306 10.1016/j.ebiom.2015.09.036 89 1 8 24 Infant|Humans|Bangladesh|Rotavirus Vaccines|Poliovirus Vaccine, Oral|Polio|*Intestinal Diseases|Antibodies, Viral|Feces 36 REG1B 26758185 mBio 2016 PMC4725020 10.1128/mBio.02102-15 23 2 2 24 Child|Humans|Cross-Sectional Studies|Blind Loop Syndrome|*Intestinal Diseases|Calprotectin|Intestine, Small|Feces|Breath Tests|Gastrointestinal Microbiome|Prevalence|Case-Control Studies|*Bacterial Infections|Inflammation|*Digestive System Abnormalities|Biomarkers|Logistic Regression 36 RELT 27932177 Transplant. Proc. 2016 10.1016/j.transproceed.2016.02.065 1 0 0 87 *Cardiac Tamponade|*Reoperation|Pericardium|Postoperative Complications|*Liver|Emergency 46 RELT 27182164 World J. Gastroenterol. 2016 PMC4858636 10.3748/wjg.v22.i18.4547 0 0 0 87 Humans|*Reoperation|*Hepatitis C, Chronic|Hepatitis C|Hepatitis C virus|*Liver|Liver Transplantation|Liver Cirrhosis|Antiviral Agents|Risk Factors|Recurrence|Kaplan-Meier Estimate 46 Resp18 26836020 Biochim. Biophys. Acta 2016 10.1016/j.bbapap.2016.01.013 1 4 0 423 PTPRN protein, human|*Receptor-Like Protein Tyrosine Phosphatases, Class 8|regulated endocrine secretory protein 18|*Nerve Tissue Proteins|Secretory Granules|Insulin|Islets of Langerhans|Exocytosis|Membrane Proteins|Protein Tyrosine Phosphatase|*Biophysics|Autoantigens|Amino Acid Sequence 23 RETNLB 27620722 Infect. Immun. 2016 PMC5116711 10.1128/IAI.00180-16 7 0 0 201 Mice|Animals|*Nematospiroides dubius|*Interleukin-17|Strongylida Infections|Th2 Cells|Intestines 152 RETNLB 27397737 Am. J. Pathol. 2016 PMC5012468 10.1016/j.ajpath.2016.04.017 2 0 0 201 Humans|Mice|Animals|*Glucose Intolerance|Diabetes Mellitus, Type 2|*Disease Susceptibility|*Mice, Knockout|Hormones, Ectopic|Goblet Cells|Intestines|RETN protein, human|Resistin|*Intestinal Diseases|Cytokines|Colon|Inflammation Mediators|Th2 Cells|Inflammation|*Gastrointestinal Diseases|*Immune System|*Cancer 152 RETNLB 27376728 J. Nutr. Biochem. 2016 10.1016/j.jnutbio.2016.05.013 3 2 0 201 Mice|Animals|*Lactobacillus salivarius|Diabetes Mellitus, Experimental|*Intestines|Dysbiosis|Intestinal Microbiota|Intestinal Mucosa|Klebsiella pneumoniae|Bacterial Translocation|Bacteria|Mice, Inbred C57BL|Anti-Bacterial Agents|Endotoxemia 152 RETNLB 27353313 Int. J. Mol. Med. 2016 10.3892/ijmm.2016.2656 9 5 0 201 STAT6 protein, human|*STAT6 Transcription Factor|Macrophage Activation|STAT3 protein, human|*STAT3 Transcription Factor|Macrophages|*Phenotypes|Lipopolysaccharides|CD163 antigen|Receptors, Cell Surface|Transductions, Signal|Interleukin-4|IL10 protein, human|IL10|Tumor Necrosis Factor-alpha|Inflammation|Interferon-gamma|Gene Expression 152 RETNLB 27166517 Elife 2016 PMC4907689 10.7554/eLife.10903 15 19 1 201 Humans|Mice|Animals|*Colitis|*Colon Cancer|*Isoforms|*Receptors, Cytoplasmic and Nuclear|Hepatocyte Nuclear Factor 4|Colon|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Gene Expression Profiles|Retnlb protein, mouse|Hormones, Ectopic 152 RHBDF1 27284064 Biochem. Soc. Trans. 2016 PMC4902136 10.1042/BST20160035 0 2 0 79 Animals|Drosophila|Drosophila Proteins|Protein Transport|Signal Transduction|Membrane Proteins|*Biological Phenomena 30 RIMS2 27537484 Neuron 2016 10.1016/j.neuron.2016.07.042 29 0 0 81 Mice|Animals|Synaptic Vesicles|RBBP8 protein, human|*Binding Proteins|Presynaptic Terminals|Synaptic Transmission|Synapses|Calcium Channels|Neurons|rab3 GTP-Binding Proteins|*Nuclear Proteins|Hippocampus|Nerve Tissue Proteins|Calcium|Mice, Knockout 35 RP1L1 27930654 PLoS Genet. 2016 PMC5145144 10.1371/journal.pgen.1006469 16 8 0 12 Humans|Animals|*Cilia|Caenorhabditis elegans|*GTPase|Bardet-Biedl Syndrome|*Protein Transport|Caenorhabditis elegans Proteins|Dynein|Flagella|Biological Transport|Retinitis Pigmentosa|Signal Transduction|Mutation|FAM161A protein, human|Eye Proteins|Rab-28 protein, C elegans|rab GTP-Binding Proteins 47 RP1L1 27623337 Invest. Ophthalmol. Vis. Sci. 2016 10.1167/iovs.16-19670 11 0 0 12 Humans|Japan|*Macular Degeneration|*Retinal Dystrophies|Electroretinography|Fluorescein Angiography|Eye Proteins|*Cohort Studies|*Genotype-Phenotype Associations|Retina|Tomography, Optical Coherence|Pedigree|Phenotype|Visual Acuity|Mutation|Asian Continental Ancestry Group|*Eye Abnormalities|Genotype|RP1L1 protein, human 47 RTTN 26940245 Clin. Genet. 2016 10.1111/cge.12771 4 0 0 72 Autosomal Recessive Primary Microcephaly|*Microcephaly|*Failure to Thrive|Comparative Genomic Hybridization|*Nervous System Malformations|*Phenotype|Dwarfism|Homozygote|Polymicrogyria|Brain|Lissencephaly|Exons|Mutations|Exome|Pedigree|Carrier Proteins|Cell Cycle Proteins|Grey Matter 21 RTTN 26846091 BMC Med Genomics 2016 PMC4743197 10.1186/s12920-016-0167-8 19 2 1 72 Humans|*Microcephaly|*Intellectual Disability|*Whole Exome Sequencing|Exome|Pedigree|Sequence Analysis, DNA 21 SBSN 28011936 J. Immunol. 2016 PMC5557335 10.4049/jimmunol.1601157 11 0 0 57 Mice|Animals|*Mice, Inbred C57BL|MHC Class II Molecules|*Lymph Nodes|*Colitis|*Genes, MHC Class II|Dendritic Cells|Peptides|Mass Spectrometry|B Cells 23 SBSN 27402194 Environ. Sci. Technol. 2016 10.1021/acs.est.6b00688 5 1 0 57 *Waste Water|*Anode|Electrolysis|Water Purification|Titanium|Electrochemistry|Antimony|Oxidation-Reduction|Chlorine|Kinetics|*Saline Solution 23 SBSN 27023521 Int J Mol Sci 2016 PMC4848891 10.3390/ijms17040435 8 12 1 57 Animals|Humans|*Nucleoprotein|*Bornavirus|*Cell Proliferation|*Apoptosis|*Cell Cycle|Glioma|Apoptosis Regulatory Proteins|Downregulation|Short Hairpin RNA|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|RNA Interference|Up-Regulation|Cell Cycle Checkpoints|Mitogen-Activated Protein Kinases|G2 Phase|Cell Division 23 SBSN 26899563 Sci Rep 2016 PMC4761926 10.1038/srep21549 7 13 1 57 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|CCND1 protein, human|Cyclin D1|Carcinoma, Squamous Cell|Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|Upregulation|Cell Line, Tumor|Cell Proliferation|beta Catenin|Down-Regulation|Cell Movement 23 SCAF1 27997587 PLoS ONE 2016 PMC5173253 10.1371/journal.pone.0168774 5 0 0 104 Animals|Mice|*Electron Transport|*C57BL Mouse|*Mitochondrial Membranes|Electron Transport Complex I|Electron Transport Complex IV|*Mutation|Oxidative Phosphorylation|Mitochondria|Isoforms|Mitochondria, Liver|Homozygotes|Allele 28 SCAF1 27775717 Nature 2016 10.1038/nature20157 42 1 0 104 Animals|Mice|*Mitochondrial Membranes|Electron Transport Complex I|Electron Transport Complex IV|Chain, Respiratory|Mitochondria|Protein Isoforms 28 SCAF1 27378395 Nutr Metab Cardiovasc Dis 2016 10.1016/j.numecd.2016.05.011 5 1 0 104 Humans|transglutaminase 2|*Transglutaminases|*GTP-Binding Proteins|*Phagocytosis|*Macrophages|Apoptosis|Signal Transduction|Atherosclerosis|Plaque, Atherosclerotic|Cell Differentiation|Cells, Cultured|Artificial Intelligence 28 SCAF1 27367025 Oncotarget 2016 PMC5226571 10.18632/oncotarget.10318 4 32 1 104 Humans|Mice|Animals|Neoplasm Recurrence, Local|*Glioma|*Macrophages|Brain Neoplasms|*Scavenger Receptor|*Disease Progression|Microglia|STAT6 protein, human|STAT6 Transcription Factor|Tumor Microenvironment|Cell Line, Tumor|Cell Proliferation|Up-Regulation|Signal Transduction|Monocytes 28 SCAF1 26892079 J. Biomed. Sci. 2016 PMC4758095 10.1186/s12929-016-0244-5 3 9 1 104 *Glycosylation|*Cysteine|*Cytoplasm|Scavenger Receptors|*Protein Domains|Alzheimer Disease|Receptors, Immunologic|Microglia|Macrophage|*Protein Transport|*Cell Movement|*Polysaccharides|Artificial Intelligence 28 Scara3 27785392 Balkan J. Med. Genet. 2016 PMC5026264 10.1515/bjmg-2015-0081 8 8 1 1145 Humans|*Diabetes Mellitus, Type 2|DNA Methylation|CpG Islands|Promoter Regions, Genetic|Epigenesis, Genetic|DNA-Binding Proteins|*Epigenetic|Cell Line, Tumor 37 Scara3 27648443 Biomed Res Int 2016 PMC5018317 10.1155/2016/1648030 1 5 1 1145 Humans|Swine|Animals|*Hepatitis E virus|*Hep G2 Cells|Hepatitis E|*Transcriptome Analysis|Viral Proteins|Downregulation|mRNA|Upregulation|HEK293 Cells 37 Scara3 27148859 Mol. Carcinog. 2016 10.1002/mc.22494 0 7 0 1145 *Downregulation|*Platelet Derived Growth Factor Receptor|EGFR protein, human|*Epidermal Growth Factor Receptor|*RNA Splicing|splicing factor 3a|Ribonucleoprotein, U2 Small Nuclear|Scavenger Receptors, Class A|Cell Death|Heat-Shock Proteins|Cell Line, Tumor|Apoptosis|*Cells, B-1|Cell Nucleus 37 Scara3 27041666 Fish Shellfish Immunol. 2016 10.1016/j.fsi.2016.03.156 0 0 0 1145 Animals|*Aeromonas hydrophila|*Carps|*Scavenger Receptors, Class A|Phylogeny|Fish Disease|Fish Proteins|Gram-Negative Bacterial Infections|*Genome|Immunity, Innate|Sequence Alignment|DNA, Complementary|Amino Acid Sequence|RNA, Messenger|Number, Gene Copy|Spleen 37 Scara3 26773601 Int J Pharm 2016 10.1016/j.ijpharm.2016.01.014 6 1 0 1145 *Blood-Brain Barrier|Endothelial Cells|Angiopep-2|*Peptides|*Scavenger Receptor|*Biological Transport|*Plasmid|Brain|Drug Delivery Systems|Transcytosis|Transfection|Endocytosis|Nanoparticles|Low Density Lipoprotein Receptor-Related Protein-1|Cells, Cultured|DNA 37 SCPEP1 27801781 Int J Mol Sci 2016 PMC5133796 10.3390/ijms17111795 7 8 0 445 Humans|Child|*MicroRNAs|*Liver|*Biomarkers|*Liver Disease|mRNA|Gene Expression Regulation|Gene Expression Profiling|Hepatocytes|Biliary Atresia|Disease Progression 47 SCPEP1 27154007 Genome Biol. 2016 PMC4858858 10.1186/s13059-016-0952-x 4 12 1 445 Mice|Animals|*Mouse Embryonic Stem Cells|*Chromatin|Embryonic Stem Cells|Pluripotent Stem Cells|Gene Expression Regulation, Developmental|Epigenesis, Genetic|Embryonic Development|Cell Differentiation 47 SCPEP1 26854235 Cell Rep 2016 PMC4758864 10.1016/j.celrep.2016.01.034 14 30 1 445 *Proto-Oncogene Proteins p21(ras)|AGO2 protein, human|*Argonaute Proteins|*Cell Transformation, Neoplastic|*Genes, ras|Cell Proliferation|Signal Transduction|MicroRNAs|Gene Silencing|Gene Expression Regulation, Neoplastic|Co-Immunoprecipitation 47 SCPEP1 26783748 Cell. Physiol. Biochem. 2016 10.1159/000438624 2 13 0 445 *Vascular Endothelial Growth Factor B|*Vascular Endothelial Growth Factor A|*Tretinoin|*Vascular Endothelial Growth Factors|*Hypoxia|NF-kappa B|Signal Transduction|Cell Hypoxia|Cell Line|RNA, Messenger 47 SCRN1 26883194 Oncotarget 2016 PMC4924679 10.18632/oncotarget.7318 3 26 1 65 Humans|*Erlotinib Hydrochloride|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Up-Regulation|Phosphatidylinositol 3-Kinases|EGFR protein, human|Epidermal Growth Factor Receptor|Protein Kinase Inhibitors|Genes, erbB-1|*Oncogenes|Drug Resistance, Neoplasm|Xenograft Model Antitumor Assays|Cell Line, Tumor|Signal Transduction|Mutation|*Oncogenesis|Cell Proliferation|Phosphorylation 21 SEC14L2 27197287 Cancer Epidemiol. Biomarkers Prev. 2016 PMC5086806 10.1158/1055-9965.EPI-16-0104 9 5 0 336 Humans|Male|*Vitamin E|*Selenium|*Prostate|Antioxidants|Prostatic Neoplasms|Dietary Supplements|Risk Factors|Polymorphism, Single Nucleotide|Genotype 55 SEC14L2 27044429 Virol. J. 2016 PMC4820862 10.1186/s12985-016-0519-1 9 2 1 336 Humans|*Human Induced Pluripotent Stem Cells|*Hepatitis C|*Hepatocyte|Hepatitis C virus|Cell Line|Virus Replication|RNA, Viral|Cell Differentiation|Host-Pathogen Interactions 55 SEC14L2 26953209 Antimicrob. Agents Chemother. 2016 PMC4862521 10.1128/AAC.02932-15 11 0 1 336 *Hepacivirus|Antiviral Agents|uridylyl-(3'-5')-adenosine|Hepatitis C, Chronic|*Replicons|*Hepatitis C|*Drug Resistance, Viral|*Dinucleoside Phosphates|Sofosbuvir|*Cell Lines|Genotype|Virus Replication|Luciferase 55 SERPINA6 28024808 J. Thorac. Cardiovasc. Surg. 2016 10.1016/j.jtcvs.2016.11.030 1 1 0 697 Infant|Humans|*Hydrocortisone|*Cardiopulmonary Bypass|Pituitary-Adrenal System|Hypothalamo-Hypophyseal System|Adrenocorticotropic Hormone|Adrenal Insufficiency|Cardiac Surgical Procedures 94 SERPINA6 27440422 Open Biol 2016 PMC4967818 10.1098/rsob.150193 5 22 1 697 Female|Animals|Swine|*Pituitary-Adrenal System|*Hypothalamo-Hypophyseal System|*Receptors, Glucocorticoid|Leukocytes, Mononuclear|Glucocorticoids|Corticotropin-Releasing Hormone|Hydrocortisone|Adrenocorticotropic Hormone|Hypothalamus|Dexamethasone 94 SERPINA6 27339896 J. Biol. Chem. 2016 PMC5016167 10.1074/jbc.M116.735258 6 0 0 697 Humans|*Transcortin|ELANE protein, human|*Leukocyte Elastase|*Pseudomonas aeruginosa|*Glycosylation|*Proteolysis|Chromatography, Liquid|Tandem Mass Spectrometry|pseudolysin, Pseudomonas aeruginosa|Bacterial Proteins|Metalloendopeptidases|Cortisol 94 SERPINA6 27061835 Clin. Endocrinol. (Oxf) 2016 10.1111/cen.13081 4 3 0 697 *Transcortin|Cortisol|Inflammation|*Rheumatoid Arthritis 94 SERPINA6 27026706 J. Biol. Chem. 2016 PMC4900275 10.1074/jbc.M116.714378 6 0 0 697 Cricetinae|Rats|Animals|*Transcortin|*Binding Protein|Phylogeny|Binding Site|Cricetulus|CHO Cells|*Steroids|Amino Acid Sequence|Cortisol|Glycosylation|*Birds|Asparagine|*Biological Evolution 94 SERPINA6 26843449 Biol. Reprod. 2016 PMC4829089 10.1095/biolreprod.115.136952 0 2 0 697 Pregnancy|Female|Mice|Animals|*Transcriptome|GTP-Binding Protein alpha Subunits, Gq-G11|Corpus Luteum|Luteal Cells|Luteolysis|Prostaglandin F2alpha|Progesterone|lysophosphatidic acid|Lysophospholipids|*Ovary|Parturition|Up-Regulation 94 SERPINA6 26829559 J. Steroid Biochem. Mol. Biol. 2016 10.1016/j.jsbmb.2016.01.013 0 0 0 697 Humans|*Transcortin|*Surface Plasmon Resonance|*Hot Temperature|Leukocyte Elastase|Enzyme-Linked Immunosorbent Assay|Antibodies, Monoclonal|Protein Binding|Epitopes|Cortisol|Temperatures 94 SERPINB7 27666198 Mol Med Rep 2016 PMC5101892 10.3892/mmr.2016.5757 0 2 1 30 Humans|*Palmoplantar Keratosis|*Chinese|Homozygote|Founder Effect|Pedigree|Mutation|Antigens, Ly|Urokinase-Type Plasminogen Activator|*Hand Deformities|Serpins|*Foot Deformities|Mainland China|SLURP1 protein, human|SERPINB7 protein, human 57 SERPINB7 26871801 Medicine (Baltimore) 2016 PMC4753896 10.1097/MD.0000000000002694 0 0 1 30 Humans|*Glomerulonephritis, IGA|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Haplotypes|Proteinuria|Odds Ratios|Case-Control Studies|Serpins|Disease Progression 57 SERPINB9 28024184 Mol. Immunol. 2016 10.1016/j.molimm.2016.12.011 3 2 0 198 *Cross-Presentation|GZMB protein, human|Granzyme B|Antigen Presentation|*Serine Proteinase Inhibitors|Dendritic Cells|CD8-Positive T-Lymphocytes|Serpins|Flow Cytometry|Membrane Proteins|*Biomarkers|Lymphocytes 133 SERPINB9 27821327 Redox Biol 2016 PMC5099269 10.1016/j.redox.2016.10.016 4 24 1 198 Animals|Mice|*Cisplatin|*Down-Regulation|*Ototoxicity|*Mice, Inbred CBA|*Cochlea|Antineoplastic Agents|Hearing Loss|Signal Transduction|Apoptosis|Auditory Brain Stem Responses|Ear, Inner|Cell Death|Lmo4 protein, mouse|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 133 SERPINB9 27513956 Int. J. Oncol. 2016 PMC5021245 10.3892/ijo.2016.3656 4 42 1 198 Animals|Humans|*Caspase-7|*MAPK, p38|*Rana catesbeiana|*N-Acetylneuraminic Acid|CASP3 protein, human|*Caspase 3|*Signal Transduction|ribonuclease B|*Ribonucleases|*Lectins|Apoptosis|Viability, Cell|Cell Proliferation|Amphibian Proteins|Antineoplastic Agents|Cell Line, Tumor|Mitochondria|Caspase Inhibitors 133 SERPINB9 27491559 Pharmacol. Res. 2016 10.1016/j.phrs.2016.07.044 2 0 0 198 Humans|Female|estrogen receptor alpha, human|*Estrogen Receptor alpha|*Down-Regulation|*Receptors, Estrogen|neotanshinlactone|*Furans|Tamoxifen|*Pyrones|Estrogen Antagonists|Antiestrogen|MCF7 Cells|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|Cell Proliferation|Transcription, Genetic|Estradiol|CCND1 protein, human 133 SERPINB9 27121069 Int. J. Oncol. 2016 10.3892/ijo.2016.3495 10 1 0 198 Humans|*Serpins|Neoplasm Recurrence, Local|MCF7 Cells|Estrogen Receptor alpha|Gene Expression Regulation, Neoplastic|Oestradiol|Estrogens|SOX2 protein, human|SOXB1 Transcription Factors|Cell Proliferation|Cell Line, Tumor|Cancer Stem Cells|Signal Transduction|CXCR4 protein, human|Receptors, CXCR4|Genistein|Peptide Hydrolases 133 SERPINB9 26993499 Cancer Immunol. Immunother. 2016 PMC4840222 10.1007/s00262-016-1819-4 6 0 1 198 Humans|*Granzymes|*Oropharyngeal Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Papillomaviridae|Carcinoma, Squamous Cell|Papillomavirus Infections|Prognosis|Lymphocytes, Tumor-Infiltrating|CD8-Positive T-Lymphocytes|*Mouth Neoplasms|squamous cell carcinoma-related antigen|Antigens, Neoplasm|Kaplan-Meier Estimate|Biomarkers, Tumor|Serpins|Head and Neck Neoplasms 133 SERPINB9 26992230 Oncotarget 2016 PMC4991381 10.18632/oncotarget.8086 5 4 1 198 Humans|*Serine|Caspase 1|interleukin-1beta-converting enzyme inhibitor|*Serpins|Monocytes|tripeptide aminopeptidase|Interleukin-1beta|*Aminopeptidases|Inflammation|endopeptidase B|*Cysteine Endopeptidases|Lipopolysaccharides|GZMB protein, human|Granzyme B|Cytokines|SERPINB9 protein, human 133 SERPINI1 27903752 Mol. Cancer Ther. 2016 10.1158/1535-7163.MCT-16-0475 13 0 0 165 Humans|*Antineoplastic Agents|Nuclear Proteins|Transcription Factors|Cell Line, Tumor|Cell Cycle Proteins|Xenograft Model Antitumor Assays|Proto-Oncogene Proteins c-myc|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Cell Proliferation|Transcription, Genetic|Hematologic Neoplasms|Downregulation|Apoptosis|*Biomarkers|OTX015|Heterocyclic Compounds, 3-Ring|Signal Transduction 31 SERPINI1 27737651 BMC Med. Genet. 2016 PMC5064884 10.1186/s12881-016-0332-0 2 2 1 165 Humans|*Hemangioma, Cavernous, Central Nervous System|KRIT1 protein, human|KRIT1 Protein|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Membrane Proteins|Carrier Proteins|Mutation|*Promoter Regions, Genetic|Genetic Predisposition to Disease|Microtubule-Associated Proteins|Polymorphism, Single Nucleotide 31 SERPINI1 27047334 Front Mol Neurosci 2016 PMC4805586 10.3389/fnmol.2016.00020 14 9 1 165 Animals|Mice|*Morphine|*MicroRNAs|*Mice, Inbred C57BL|*Analgesics|Drug Tolerance|Analgesics, Opioid|mRNA|Bioinformatics|Pain|Gene Expression Regulation 31 SERPINI1 26892864 Cancer Sci. 2016 PMC4970828 10.1111/cas.12909 11 8 1 165 Humans|Mice|Animals|*Epithelial-Mesenchymal Transition|Mice, Nude|CDH1 protein, human|E Cadherin|*Colorectal Cancer|Vimentin|*Colonic Neoplasms|HCT116 Cells|Cell Movement|Antigens, CD|Gene Expression Regulation, Neoplastic|Downregulation|Wnt Pathway|Transforming Growth Factor beta1|Cell Line, Tumor|*Embryo Implantation|AGR2 protein, human|Proteins 31 SETMAR 28038463 Oncotarget 2016 PMC5354774 10.18632/oncotarget.14218 2 4 0 173 Humans|*Glioblastoma|Brain Tumors|Neoplastic Stem Cells|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|mRNA|Alternative Splicing|DNA Repair|*Isoforms|*Protein Stability|DNA End-Joining Repair 44 SETMAR 27974460 J. Biol. Chem. 2016 PMC5270484 10.1074/jbc.M116.745646 5 4 0 173 Humans|exodeoxyribonuclease I|*Exodeoxyribonucleases|EXO1 protein, human|*DNA Repair Enzymes|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|*DNA, Single-Stranded|DNA Replication|DNA Repair|DNA Damage|Histones|DNA|DNA Cleavage|*Chromosome Structures 44 SETMAR 27599863 Acta Crystallogr F Struct Biol Commun 2016 PMC5012212 10.1107/S2053230X16012723 0 0 0 173 Humans|*Selenomethionine|*Crystallization|Transposase|Transposable Elements|Amino Acid Sequence|Base Sequence|DNA-Binding Proteins|Inverted Terminal Repeat|Histone-Lysine N-Methyltransferase 44 SETMAR 27262532 DNA Repair (Amst.) 2016 10.1016/j.dnarep.2016.05.011 17 0 0 173 *DNA Breaks, Double-Stranded|*Phosphodiesterases|DNA End-Joining Repair|*Endonucleases|*DNA Repair|RBBP8 protein, human|Nuclear Proteins|*DNA|MRE11 Homologue Protein|DNA-Binding Proteins|Carrier Proteins|Poly-ADP-Ribose Binding Proteins|SETMAR protein, human|Histone-Lysine N-Methyltransferase 44 SETMAR 26757780 Leuk. Lymphoma 2016 10.3109/10428194.2015.1121257 6 2 1 173 Humans|Adult|*Lymphoma, Mantle-Cell|*SOX11 Transcription Factor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Signaling|*Biological Phenomena|SOX11 protein, human 44 SEZ6L 27716410 Mol Neurodegener 2016 PMC5053352 10.1186/s13024-016-0134-z 0 15 1 15 Animals|Mice|*Amyloid Precursor Protein Secretases|*Aspartic Acid Endopeptidases|Proteomics|*Neurons|Amyloid beta-Protein Precursor|TYRP1 protein, human|*Membrane Glycoproteins|Alzheimer Disease|Nerve Tissue Proteins|*Seizure|Membrane Proteins|Bace1 protein, mouse|Sez6 protein, mouse 21 SEZ6L 27685260 Sci Rep 2016 PMC5041581 10.1038/srep33439 0 1 1 15 Dogs|Humans|Animals|Adolescent|Genome-Wide Association Study|*Genome|*Genomics|Chromosome Mapping|Genotype|*Communication|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Domestication|Genetic Linkage|Breeding|Social Behaviors|Genetic Marker|Skills, Social 21 SEZ6L 26769141 Mod. Pathol. 2016 10.1038/modpathol.2015.144 0 2 0 15 *Stomach|Gastric Mucosa|Helicobacter Infections|Gastric Cancers|*Carcinogenesis|DNA Methylation|CpG Islands|Gastritis|Helicobacter pylori|Metaplasia|Cell Transformation, Neoplastic|Epigenesis, Genetic|*Sequencing, Next-Generation|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Genes, Tumor Suppressor|Prognosis|osteoblast cadherin 21 SEZ6L 26747525 BMC Genomics 2016 PMC4706689 10.1186/s12864-015-2359-6 20 2 1 15 Humans|IL10 protein, human|*Interleukin-10|*Head and Neck Cancer|*Disease Progression|Carcinoma, Squamous Cell|Prognosis|*Signal Transduction|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Mutations|Integrins 21 SHROOM2 27802160 J. Cell. Sci. 2016 PMC5394778 10.1242/jcs.188185 22 1 0 47 *Occludin|*Actins|Tight Junction|*Actin Cytoskeleton|Zonula Occludens-1 Protein|Protein Binding|Phosphoproteins|Epithelial Cells|Cell Line|*Morphogenesis 26 SIDT2 27987306 FEBS Lett. 2016 10.1002/1873-3468.12528 3 0 0 73 Humans|HEK293 Cells|SIDT2 protein, human|Nucleotide Transport Proteins|Lysosomes|neutrophil basic proteins|*Blood Proteins|Membrane Proteins|*Antimicrobial Cationic Peptides|Plasma Membrane 25 SIDT2 27846365 Autophagy 2016 PMC5245770 10.1080/15548627.2016.1248019 5 0 0 73 Humans|*Lysosomes|TYRP1 protein, human|*Membrane Glycoproteins|*DNA|RNA|Lysosomal-Associated Membrane Protein 2|Autophagy|Nucleotide Transport Proteins|*Intracellular Membranes|*Biological Transport|HeLa Cells|Membrane Proteins|RNA Interference|Membrane Transport Proteins|SIDT2 protein, human 25 SIDT2 27233614 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.05.122 4 0 0 73 Mice|Animals|*Non-alcoholic Fatty Liver Disease|*Endoplasmic Reticulum Stress|Endothelial Cells|Liver|Hepatocytes|Lipid Metabolism|Tunicamycin|Triglycerides|Diet, High-Fat|Aspartate Transaminase|Lipid Droplets|Membrane Protein|Fatty Acids, Nonesterified|ERN1 protein, human|Protein-Serine-Threonine Kinases|mRNA|Endoribonucleases|Sidt2 protein, mouse 25 SIDT2 27046251 Autophagy 2016 PMC4836006 10.1080/15548627.2016.1145325 12 3 1 73 Humans|*RNA|*RNA Transport|*Lysosomes|Lysosomal-Associated Membrane Protein 2|Autophagy|Nucleotide Transport Proteins|Membrane Proteins|*Biological Transport|HeLa Cells|RNA Interference|RNA Degradation|Membrane Transport Proteins|SIDT2 protein, human 25 SIDT2 26884831 Int J Clin Exp Pathol 2016 PMC4730044 5 1 0 73 Mice|Animals|*Insulin Secretion|Diabetes Mellitus, Type 2|TYRP1 protein, human|*Membrane Glycoproteins|B-insulin|Insulin|Islets of Langerhans|Glucose|*Lysosomes|Impaired Glucose Tolerance|SNARE Proteins|Carrier Proteins|*Intracellular Membranes|N-Ethylmaleimide-Sensitive Proteins|Biotin|Lysosome-Associated Membrane Glycoproteins|Sidt2 protein, mouse|Membrane Proteins 25 SIDT2 26744456 J. Mol. Endocrinol. 2016 10.1530/JME-15-0227 3 2 0 73 Mice|Animals|NAADP|*Insulin|*Calcium|*Secretory Vesicles|*NADP|*Insulin, Regular, Human|Calcium Signaling|Islets of Langerhans|ADP-ribosyl Cyclase 1|*Calcium, Dietary|Insulin Secretion|Glucose|Knockout Mouse|Membrane Glycoproteins|Sidt2 protein, mouse|Membrane Proteins 25 SKA3 27667719 Sci Rep 2016 PMC5036024 10.1038/srep34042 8 8 1 193 Animals|*Chromosome Segregation|*Microtubules|Kinetochore|Microtubule-Associated Proteins|Mitosis|Tubulin|Anaphase|NDC80 protein, human|Nuclear Proteins|Caenorhabditis elegans Proteins|Chromosomal Proteins, Non-Histone|*Protein Binding|Caenorhabditis elegans|Cytoskeletal Proteins|SKA1 protein, C elegans 37 SKA3 27495871 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.08.002 3 4 0 193 Animals|Humans|*Separase|*Biotin|Centrioles|Anaphase|Kinetochores|Mitosis|Chromatids|Cell Cycle Proteins|Centrosome|Chromosome Segregation|Chromosomal Proteins, Non-Histone|Metaphase|Caenorhabditis elegans|Histone|Protein-Serine-Threonine Kinases|DNA-Binding Proteins|NAP1L4 protein, human|Nuclear Proteins 37 SKA3 27329586 Oncotarget 2016 PMC5216762 10.18632/oncotarget.9960 17 23 1 193 Humans|AURKA protein, human|*Aurora Kinase A|Apoptosis|Cross-Sectional Studies|Cell Line, Tumor|G2 Phase Cell Cycle Checkpoints|*Adenomas|*Colorectal Cancer|Cell Transformation, Neoplastic|Adenocarcinomas|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Up-Regulation|Chromosome Instability|DNA Copy Number Variations|Disease Progression|DSN1 protein, human|Chromosomal Proteins, Non-Histone 37 SKOR1 27421018 Genet. Mol. Res. 2016 10.4238/gmr.15028311 4 0 0 30 Adult|Humans|Child|*Whole Exome Sequencing|Genome-Wide Association Study|*Exome|Diabetes Mellitus, Type 2|Thailand|*Obesity|Body Mass Index|Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Allele Frequency|Genotype|Proteins|Case-Control Studies|ALOX5AP protein, human|5-Lipoxygenase-Activating Proteins|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 24 SLC16A12 27259265 Oncotarget 2016 PMC5190073 10.18632/oncotarget.9764 6 1 1 24 Humans|*Helicobacter pylori|*CpG Islands|*Telomere Shortening|*Gastric Mucosa|Helicobacter Infections|*Promoter Regions, Genetic|Gastritis|DNA Methylation|Stomach Neoplasms|Epigenesis, Genetic|Cell Transformation, Neoplastic 24 SLC16A12 26861414 Nat Commun 2016 PMC4749955 10.1038/ncomms10577 67 5 5 24 Pregnancy|Humans|Female|Infant, Newborn|*DNA Methylation|*Folate|*Epigenome|Epigenesis, Genetic|Epigenetics|*DNA|Neural Tube Defects|DNA-Binding Proteins|Fetal Development|Transcription Factors|Prenatal Exposure Delayed Effects|Fetal Blood|Genome-Wide Association Study|OPCML protein, human|Cell Adhesion Molecules|GPI-Linked Proteins|PRSS21 protein, human|Serine Endopeptidases 24 SLC16A9 27364523 BMC Neurosci 2016 PMC4929735 10.1186/s12868-016-0274-7 5 1 1 89 Animals|Mice|*Kidney|Neurons|Monocarboxylic Acid Transporters|RNA, Messenger|Brain 30 SLC22A9 27199754 Front Pharmacol 2016 PMC4845040 10.3389/fphar.2016.00111 11 7 1 139 Humans|*MicroRNAs|*Rifampin|*Hepatocytes|*Transporters, Membrane|*Gene Expression|ATP-Binding Cassette Transporters|Multidrug Resistance-Associated Proteins|RNA, Messenger|Cells, Cultured|Liver|*Biological Transport 30 SLC25A24 27887572 BMC Genomics 2016 PMC5124223 10.1186/s12864-016-3310-1 21 6 0 148 Pregnancy|Humans|Child|Female|Infant, Newborn|Cohort Studies|*Epigenesis, Genetic|CpG Islands|Maternal Exposure|DNA Methylation|Cotinine|Prenatal Exposure Delayed Effects|Smoking|Fetal Blood|Genome-Wide Association Study|Tobacco Smoking|Mother|Norway 27 SLC25A24 26850042 Physiol. Genomics 2016 10.1152/physiolgenomics.00042.2015 1 0 0 148 Pregnancy|Cattle|Animals|Female|*Luteal Phase|*Estrous Cycle|*Endometrium|*Fertility|*Gene Expression|Gene Chip|Embryo Loss|Gene Expression Profiling|Reproduction|Conception 27 SLC25A38 27476175 J. Biol. Chem. 2016 PMC5025666 10.1074/jbc.M116.736876 10 1 0 20 Humans|*Saccharomyces cerevisiae|*Glycine|X-linked sideroblastic anemia|Anemia, Sideroblastic|Mitochondrial Membrane Transport Proteins|*Mitochondria|*Anemia|*Yeast, Dried|Heme b|Genetic Diseases, X-Linked|*Heterozygote|Electron Transport|Erythroblasts|Slc25a38 protein, human 35 SLC25A38 27038157 Pediatr Blood Cancer 2016 10.1002/pbc.25981 2 0 0 20 Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Glycine|Genetic Diseases, X-Linked|Mitochondrial Membrane Transport Proteins|Mutations|Folate|Dietary Supplements|Slc25a38 protein, human 35 SLC25A38 26821380 PLoS Genet. 2016 PMC4731144 10.1371/journal.pgen.1005783 17 17 1 20 Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Glycine|*Folate|*Genetic Diseases, X-Linked|Mitochondrial Membrane Transport Proteins|Haem|Mutations|Saccharomyces cerevisiae|Mitochondria|Hemoglobin|Iron|Slc25a38 protein, human 35 SLC25A38 26813789 J. Cell. Sci. 2016 PMC4813315 10.1242/jcs.176792 10 12 0 20 Humans|*Membrane Fusion|*Mitochondria|Protein, Mitochondrial|Mitochondrial Fusion|Mitochondrial Membranes|GTP Phosphohydrolases|Mitochondrial Membrane Transport Proteins|Microtubule-Associated Proteins|Membrane Proteins|Apoptosis|HeLa Cells|Ubiquitin-Protein Ligases|Reactive Oxygen Species|Proteolysis|Membrane Fusion Proteins|DNM1L protein, human|MARCH5 protein, human|Slc25a38 protein, human 35 SLC31A2 27157188 Metallomics 2016 PMC5025354 10.1039/c6mt00076b 14 27 0 125 Humans|Female|Mice|Animals|*Cisplatin|*Copper Transport Proteins|*Molecular Chaperones|Ovarian Neoplasms|Antineoplastic Agents|Drug Resistance, Neoplasm|Cation Transport Proteins|Copper|Tumor Cells, Cultured|Cell Lines|ATOX1 protein, human|Metallochaperones|Atox1 protein, mouse|Ctr1 protein, mouse|CTR2 protein, mouse 28 SLFN12 27718235 Eur. J. Immunol. 2016 PMC5244668 10.1002/eji.201646405 2 12 0 86 Adult|Humans|PTPRC protein, human|*Leukocyte Common Antigens|Lymphocyte Activation|CD28 Antigens|T-Lymphocyte Subsets|Lupus Erythematosus, Systemic|Interleukin-2|Cytokines|Rheumatoid Arthritis|Upregulation|Signal Transduction|Cell Proliferation|Phagocytes 24 SLFN12 26857655 Mol. Biol. Rep. 2016 10.1007/s11033-016-3946-6 2 0 0 86 Humans|*DNA Methylation|MAML1 protein, human|HTATIP2 protein, human|*Transcription Factors|CpG Islands|*Gene Expression|Homeodomain Proteins|Oligonucleotide Array Sequence Analysis|Genes, Homeobox|Acetyltransferases|SOXC Transcription Factors|*Kidney 24 SMPDL3B 27836988 FASEB J. 2016 PMC6137603 10.1096/fj.201600618R 5 1 0 44 *Podocytes|*Sphingomyelin Phosphodiesterase|*Cyclic Nucleotide Phosphodiesterases, Type 3|Kidney Glomerulus|Ceramides|Kidney Diseases|*Kidney|Rituximab|Proteinuria|Sphingolipids|Antineoplastic Agents 23 SMPDL3B 27687724 J. Biol. Chem. 2016 PMC5104931 10.1074/jbc.M116.755801 6 0 0 44 Animals|Mice|*Sphingomyelin Phosphodiesterase|*Phosphodiesterase 3B|*Substrate Specificity|Sphingomyelins|Active Site|Signal Transduction|Adenosine Triphosphate|Amino Acid Sequence|Crystallography, X-Ray|Binding Site|Phosphocholine|Protein Domains|Models, Molecular 23 SPAG16 27396817 Autoimmun Rev 2016 10.1016/j.autrev.2016.07.008 11 0 1 28 Humans|*Multiple Sclerosis|Multiple Sclerosis, Primary Progressive|*B Cells|*Disease Progression|Multiple Sclerosis, Relapsing-Remitting|Central Nervous System|Meninges|Autoantibodies|Inflammation|Gliosis 28 SPANXA1 27323831 Oncotarget 2016 PMC5190107 10.18632/oncotarget.10088 8 35 1 37 Male|*Epithelial-Mesenchymal Transition|*Lung Adenocarcinomas|Lung Cancer|*Signal Transduction|Snail Family Transcription Factors|Adenocarcinoma|CDH1 protein, human|E Cadherin|Cell Line, Tumor|Cell Movement|*Antineoplastic Agents|Gene Expression Regulation, Neoplastic|Downregulation|Up-Regulation|Antigens, CD 27 SPANXA1 26895102 Oncotarget 2016 PMC4924746 10.18632/oncotarget.7408 18 34 1 37 Humans|Male|*Testis|Neoplasm Invasiveness|Cell Proliferation|Cell Movement|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|Tumor Cells, Cultured|Apoptosis|Lung Neoplasms|Actin|CTAG2 protein, human|Antigens, Neoplasm|Antigens, Surface 27 SPANXA1 26885621 Oncotarget 2016 PMC4924690 10.18632/oncotarget.7359 9 4 1 37 Humans|Male|*Prostate|*Cancer Biomarkers|Proteomics|Early Detection of Cancer|*Prostate Cancer|Prostate-Specific Antigen|Benign Prostatic Hyperplasia|Antigens, Neoplasm|*African Continental Ancestry Group|Autoantibodies|*Cohort Studies|Africa 27 SPATA16 27918162 Ceska Gynekol 2016 0 0 0 7 Humans|Male|*Spermatogenesis|Infertility, Male|*Mutations|Chromosomes, Human, Y|*Fertility|Chromosome Deletion|*DNA|Reproduction 33 SPATA16 27441053 Int J Fertil Steril 2016 PMC4948072 10.22074/ijfs.2016.4910 1 1 0 7 Humans|Male|*Teratozoospermia|*Genotype|Infertility, Male|Spermatozoa|Gene Deletion|Exons|Point Mutation|Homozygote|Membrane Proteins|Mutations|DPY19L2 protein, human 33 SPATA16 27086357 J. Assist. Reprod. Genet. 2016 PMC4889487 10.1007/s10815-016-0715-3 11 0 0 7 Humans|Male|Infertility, Male|Spermatozoa|Homozygote|Vesicular Transport Proteins|Point Mutation|Membrane Proteins|Gene Deletion|Mutation|Homeodomain Proteins|SPATA16 protein, human 33 SPATA16 26931031 Zhonghua Nan Ke Xue 2016 0 0 0 7 Humans|Male|Mice|Animals|*Acrosome|*Sperm|*Spermiogenesis|Sperm Head|Spermatids|Golgi Apparatus|Infertility, Male|Nuclear Membrane|Adaptor Proteins, Signal Transducing|STX2 protein, human|Syntaxin-2|DPY19L2 protein, human|Membrane Proteins|KDM3A protein, human|Jumonji Domain-Containing Histone Demethylases|Gopc protein, mouse|Carrier Proteins 33 srpx 26805783 Am. J. Hum. Genet. 2016 PMC4746331 10.1016/j.ajhg.2015.12.003 24 0 1 33 Humans|*Genome-Wide Association Study|*Platelet Count|*Hispanic Americans|Alleles|Gene Frequency|Genetic Loci|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|European Continental Ancestry Group|Genotype|Platelets 50 STK17B 27295129 Cell Cycle 2016 PMC5053590 10.1080/15384101.2016.1198862 11 37 1 215 Humans|*Cell Cycle Genes|HeLa Cells|Phosphatidylinositol 3-Kinases|*Sequencing, Next-Generation|Epigenesis, Genetic|*Drug Design|*Antineoplastic Agents|Gene Regulatory Networks|DNA Methylation|Gene Expression Regulation, Neoplastic|*Epigenetic|MicroRNAs|Systems Biology|Data Mining|Cell Cycle|Cell Proliferation|ARID5B protein, human|DNA-Binding Proteins 32 STK17B 27106709 Bioorg. Med. Chem. Lett. 2016 10.1016/j.bmcl.2016.03.111 2 0 0 215 indirubin|Molecular Docking Simulation|*Indoles|Serine Threonine Kinase|Structure-Activity Relationship|Protein Kinase Inhibitors|Molecular Structure|Drug Discovery|Small Molecule Libraries|Dose-Response Relationship, Drug|Binding Site 32 STK40 27899448 J. Biol. Chem. 2016 PMC5217693 10.1074/jbc.M116.719849 3 1 0 141 Mice|Animals|*Muscle Development|HDAC5 protein, human|Histone Deacetylases|*Cell Differentiation|Myocyte Enhancer Factor 2|Myoblasts|Muscle, Skeletal|Signal Transduction|Phosphorylation|Repressor Proteins|Gene Expression Regulation|Downregulation|Protein-Serine-Threonine Kinases|Serine|Stk40 protein, mouse 24 STK40 26918602 Oncotarget 2016 PMC4905434 10.18632/oncotarget.7561 11 6 1 141 Humans|Rats|Animals|*Esophageal Cancer|Esophageal Squamous Cell Carcinoma|*RNA, Micro|Carcinoma, Squamous Cell|Esophagus|Gene Expression Regulation, Neoplastic|Downregulation|Cell Proliferation|Cell Movement|Gene Expression Profiling|Genes, Tumor Suppressor|Cell Line, Tumor|Oncogenes|Apoptosis Regulatory Proteins|Zinc|PDCD4 protein, human|RNA-Binding Proteins|Pdcd4 protein, rat 24 STK40 26732326 Asian-australas. J. Anim. Sci. 2016 PMC4698687 10.5713/ajas.15.0476 2 0 1 141 Animals|*Milk|*Polymorphism, Single Nucleotide|Breeding|Phenotype|Natural Selection|Quantitative Trait, Heritable|Genotype|Models, Genetic|Pedigree|Genomics 24 STYX 28007894 EMBO J. 2016 PMC5286380 10.15252/embj.201694795 8 5 0 164 Humans|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|F-Box Proteins|Ubiquitin Ligase, SCF|Cell Cycle Proteins|Ubiquitin-Protein Ligases|Cullin Proteins|Ubiquitination|*Protein Domains|Cytoplasm|Cell Proliferation|STYX protein, human|Nuclear Proteins|Intracellular Signaling Peptides and Proteins 64 STYX 27514805 Methods Mol. Biol. 2016 10.1007/978-1-4939-3746-2_9 0 0 0 164 Humans|Animals|Proteomics|Apoptosis Regulatory Proteins|Binding Protein|Intracellular Signaling Peptides and Proteins|Phosphorylation|Apoptosis|Nuclear Proteins|Signal Transduction|MAP Kinase Signaling System|HeLa Cells|Protein Binding|Phosphatases|STYX protein, human 64 STYX 27503052 BMC Syst Biol 2016 PMC4977902 10.1186/s12918-016-0318-8 5 0 1 164 *In Silico|Computer Graphics|Software|*Computers|User-Computer Interface|Models, Biological|*Cancer 64 SVOP 27617181 Transl Vis Sci Technol 2016 PMC5015923 10.1167/tvst.5.4.15 4 0 1 115 *Visual Field Tests|*Feasibility Studies|Visual Fields|*Saccades|Vision Disorders|Algorithms|*Data Collection 26 SVOP 26740608 Br J Ophthalmol 2016 10.1136/bjophthalmol-2015-307208 3 0 1 115 Child|Adult|Humans|*Visual Field Tests|*Visual Pathways|*Cohort Studies|Visual Field|*Saccades|Vision Disorders|*Blindness|*Deafness|*Disabled Persons|*Gray Matter 26 SWAP70 27806292 Cell Rep 2016 PMC5149533 10.1016/j.celrep.2016.10.021 12 38 0 162 Humans|*Actin Cytoskeleton|*Phagocytosis|Phagosomes|Actin|Guanine Nucleotide Exchange Factors|Nuclear Proteins|rac1 GTP-Binding Protein|DNA-Binding Proteins|cdc42 GTP-Binding Protein|Minor Histocompatibility Antigens|Microfilament Proteins|Cell Line|SWAP70 protein, human 81 SWAP70 27561029 PLoS ONE 2016 PMC4999197 10.1371/journal.pone.0161060 3 7 1 162 Mice|Animals|*Hematopoietic Stem Cells|*Cell Differentiation|Hematopoiesis|Cell Lineage|TYRP1 protein, human|*Membrane Glycoproteins|Bone Marrow|B-Lymphocytes|Mice, Knockout|DNA-Binding Proteins|Cell Count|Bone Marrow Transplantation 81 SWAP70 26816213 2016 PMC5825185 10.1002/art.39599 4 7 0 162 Mice|Animals|*T-Lymphocytes, Regulatory|interferon regulatory factor-4|Interferon Regulatory Factors|IL10 protein, human|Interleukin-10|DNA-Binding Proteins|B Cells|Nuclear Proteins|Mice, Knockout|Minor Histocompatibility Antigens|Guanine Nucleotide Exchange Factors 81 TARBP1 27253715 ACS Chem. Biol. 2016 PMC5199234 10.1021/acschembio.6b00145 7 5 0 41 Humans|*HIV-1|*RNA Recognition Motif|HIV Long Terminal Repeat|tat Gene Products, Human Immunodeficiency Virus|*Response Element|*Activation, Transcription|HIV Infections|RNA, Viral|Transcription, Genetic|Nucleic Acid Conformation|Binding Sites|Trans-Activator|Mutagenesis 26 TARBP1 27040643 Mol Biosyst 2016 10.1039/c5mb00827a 10 0 1 41 Humans|*Carcinoma, Hepatocellular|*Hepacivirus|*Liver Neoplasms|*DNA Copy Number Variations|*Systems Biology|*Hepatitis C|Liver Cirrhosis|Liver|Hepatocyte|Disease Progression|Chromosomes|BCAT1 protein, human|Transaminases|SMYD3 protein, human|Histone-Lysine N-Methyltransferase 26 TBPL1 27696626 Genes Cells 2016 10.1111/gtc.12441 0 1 0 1191 Humans|*Transcription Factor TFIIA|*TATA-Binding Protein|*TATA Box Binding Protein-Like Proteins|*Proteasome Endopeptidase Complex|TATA Box|UBB protein, human|*Ubiquitin|Gene Expression Regulation|Promoter Regions, Genetic|Gene Expression|HeLa Cells|Mutation 28 TBPL1 27576952 Sci Rep 2016 PMC5006001 10.1038/srep32069 4 26 1 1191 Male|Mice|Animals|*Transcription Factor TFIIA|*Testis|*Haploidy|TATA-Binding Protein-Related Factors|Spermatogenesis|Transcription Factor|Spermatids|TATA-Box Binding Protein|Transcription, Genetic|RNA Polymerase II|Gene Expression Regulation|Promoter Regions, Genetic|TAF7L protein, mouse|Transcription Factor TFIID|TATA-Binding Protein Associated Factors 28 TBPL1 26871633 Cell 2016 PMC4762449 10.1016/j.cell.2016.01.036 44 30 4 1191 Humans|*Telomere|Telomeric Repeat Binding Protein 2|*Heterochromatin|Telomeric Repeat Binding Protein 1|Chromatin|Histone|DNA Damage 28 TBX22 27699475 Hum. Genet. 2016 PMC5065589 10.1007/s00439-016-1733-z 9 10 1 28 Humans|Animals|Male|Cleft Lip|Cleft Palate|*Siblings|PAX9 Transcription Factor|MSX1 Transcription Factor|Anodontia|KMT2D protein, human|DNA-Binding Proteins|Genotype|Phenotype|Transcription Factors|AXIN2 protein, human|Axin Protein|*Rhabdomyosarcoma, Alveolar|*Molar|Neoplasm Proteins|IRF6 protein, human|Interferon Regulatory Factors 52 TDRD3 27582462 Proc. Natl. Acad. Sci. U.S.A. 2016 PMC5035855 10.1073/pnas.1605517113 12 4 0 132 *B-DNA|*Tudor Domain|RNA|Amino Acid Sequence|DNA Topoisomerases, Type I|Protein Binding|DNA|*Isomerases|Gene Expression 25 TDRD3 27257063 Nucleic Acids Res. 2016 PMC4994864 10.1093/nar/gkw508 18 13 1 132 Humans|Animals|*RNA|Escherichia coli|*Prevalences|*Polyribosomes|TOP1 protein, human|DNA Topoisomerase|Supercoiled DNA|DNA|Amino Acid Sequence|Cloning, Molecular|Proteins|mRNA Translation|*Isomerases 25 TENM3 27951453 Aquat. Toxicol. 2016 10.1016/j.aquatox.2016.12.003 4 0 0 39 Animals|*Zebrafish|*Antibiotic|*RNA, Long Noncoding|Tetracyclines|Fluoroquinolones|Zebrafish Proteins|*High-Throughput Nucleotide Sequencing|Water Pollutants, Chemical|*Ketones 28 TENM3 27374343 Curr. Biol. 2016 PMC4963213 10.1016/j.cub.2016.05.035 16 0 1 39 Animals|*Retina|Retinal Ganglion Cells|Amacrine Cells|*Orientation|Visual Pathways|Dendrites|*Orientation, Spatial|Presynaptic Terminals|Zebrafish 28 TENM3 27103084 Am. J. Med. Genet. A 2016 10.1002/ajmg.a.37667 8 0 0 39 Humans|Microphthalmia and mental deficiency|*Microphthalmos|*Coloboma|*Microcephaly|*Brain Diseases, Metabolic, Inborn|*Intellectual Disability|*Corneal Opacity|Anophthalmia|Homozygote|Exome|Eye|Heterozygote|Mutation|Phenotype|Pedigree|Nerve Tissue Proteins|Membrane Proteins|TENM3 protein, human 28 TEX19 26826184 J. Cell. Sci. 2016 PMC4813292 10.1242/jcs.179218 24 0 1 48 *Oogenesis|Oocytes|mRNA Cleavage and Polyadenylation Factors|Meiosis|Polyadenylation|RNA-Binding Proteins|mRNA|mRNA, Maternal|3' Untranslated Regions|Xenopus Proteins|Protein Biosynthesis|Transcription Factors|Cell Cycle Proteins|Cytoplasm 20 TFEC 27928896 J Gene Med 2016 10.1002/jgm.2936 5 0 0 72 Humans|Adult|*Leukemia, Lymphocytic, Chronic, B-Cell|RNA Splicing Factors|Immunoglobulin Variable Region|Immunoglobulin Heavy Chains|Prognosis|Receptor, Notch1|Mutations|*Genomics|Phosphoproteins|Tumor Suppressor Protein p53|Databases, Genetic|Gene Expression 93 tiprl 27489114 Sci Rep 2016 PMC4973239 10.1038/srep30813 3 9 1 1859 Humans|*Binding Site|Protein Phosphatase 2|Intracellular Signaling Peptides and Proteins|Signal Transduction|Subunits, Catalytic|Phosphorylation|*Protein Domains|HEK293 Cells|Apoptosis|TIPRL protein, human 34 tiprl 27485451 Cancer Res. 2016 10.1158/0008-5472.CAN-15-3342 22 7 0 1859 Humans|Female|Glycogen Synthase Kinase 3|*Uterine Cancer|Cystadenocarcinoma, Serous|Endometrial Carcinoma|*Mutations|Protein Phosphatase 2A|Carcinosarcoma|Ovarian Neoplasms|Oncogenesis|*Cell Transformation, Neoplastic|Mutations, Missense|PPP2R1A protein, human 34 TLE6 27525657 J. 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Genet. 2016 PMC5125147 10.1007/s10815-016-0788-z 7 0 0 17 Humans|Animals|Oocytes|Zygote|Blastocyst|Embryonic Development|*Cytoplasm|Embryo, Mammalian|Gene Expression Regulation, Developmental|Amino Acid Sequence|Transcription Factors|Protein Binding|RNA, Messenger|Divisions, Cell 23 TM4SF5 27816969 Oncotarget 2016 PMC5346706 10.18632/oncotarget.13005 7 9 0 210 Mice|Animals|Carcinoma, Hepatocellular|Liver Neoplasms|*Antibodies, Monoclonal, Humanized|*Colon Cancer|Antibodies, Monoclonal|*Disease Models, Animal|*Peptides|*Vaccines, Subunit|*Lung Neoplasms|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Motility|Cell Proliferation|Membrane Proteins|vaccin|*Antigens, Bacterial|Gene Expression Regulation, Neoplastic|Immunoglobulin G 57 TMC8 27899077 BMC Cancer 2016 PMC5129199 10.1186/s12885-016-2960-3 1 5 0 65 Humans|Female|*Uterine Cervical Neoplasms|*Case-Control Studies|Greece|SNPs|Cervical Intraepithelial Neoplasia|Genetic Predisposition to Disease|fas Receptor|Genotype|Asian Continental Ancestry Group|Odds Ratio 50 TMC8 27896283 Mol Genet Genomic Med 2016 PMC5118205 10.1002/mgg3.237 13 4 1 65 Child, Preschool|Humans|Child|Molluscum Contagiosum|Phenotype|Microfilament Proteins|Warts|Mutation|Skin|*Skin Diseases 50 TMC8 29937814 J Otol 2016 PMC6002587 10.1016/j.joto.2016.06.001 1 0 0 65 *High-Throughput Nucleotide Sequencing|*Hearing Loss, Sudden|*Hearing Loss, Sensorineural|*Hearing Loss, Bilateral|*Primary Immunodeficiency Diseases|Mutation 50 TMC8 27097911 Cancer Causes Control 2016 10.1007/s10552-016-0749-y 1 0 0 65 Humans|Female|*Human Papilloma Virus|*Papillomavirus Infections|*Squamous Cell Carcinoma of Head and Neck|*Squamous Cell Carcinoma|Head and Neck Neoplasms|Laryngeal Neoplasms|Cervical Cancer|DNA, Viral|*Neck|*Mucous Membrane|Polymorphism, Single Nucleotide|Membrane Proteins|*Head|TMC6 protein, human|TMC8 protein, human 50 tmco1 27707548 Ophthalmology 2016 PMC5121091 10.1016/j.ophtha.2016.08.036 7 6 0 185 *Alleles|*Ocular Hypertension|Glaucoma, Primary Open Angle|*Glaucoma|Intraocular Pressure|Optic Disk|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Tetrahymenina 42 tmco1 27687253 J Negat Results Biomed 2016 PMC5043619 10.1186/s12952-016-0060-1 6 3 1 185 Humans|*Risk Factors|Saudi Arabia|*Glaucoma, Primary Open Angle|*Cohort Studies|Gene Frequency|Intraocular Pressure|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Genotype|Case-Control Studies 42 TMEFF1 26998585 Colorectal Dis 2016 10.1111/codi.13336 11 2 0 69 *B-DNA|*Colorectal Cancer|*DNA Methylation|Early Detection of Cancer|Feces|Biomarkers, Tumor|Promoter Regions, Genetic|*Colonic Neoplasms 26 TMEM135 27863209 Elife 2016 PMC5117855 10.7554/eLife.19264 14 19 0 40 Mice|Animals|Mitochondrial Dynamics|GTP Phosphohydrolases|Mitochondria|Oxidative Stress|Retinal Diseases|Retina|Aging|Mutation 20 TMEM135 27760563 Biol. Direct 2016 PMC5072337 10.1186/s13062-016-0157-y 9 7 1 40 Mitochondrial Membrane Transport Proteins|Saccharomyces cerevisiae Proteins|Inner Mitochondrial Membrane|Saccharomyces cerevisiae|Mitochondria|Membrane Transport Proteins|Carrier Proteins|Protein Transport|Amino Acid Sequence|Membrane Proteins|Sequence Homology, Amino Acid|Repressor Proteins|TIM17 protein, S cerevisiae|TIM22 protein, S cerevisiae 20 TMEM163 27473260 Respir. Res. 2016 PMC4966770 10.1186/s12931-016-0410-z 2 2 1 9 Humans|Genome-Wide Association Study|*Lung|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Genetic Predisposition to Disease|Forced Expiratory Volume|Genotype|Carrier Proteins|mRNA 22 TMEM163 27393345 Neurobiol. Aging 2016 PMC4976046 10.1016/j.neurobiolaging.2016.06.001 6 0 0 9 Humans|*Parkinson Disease|Genome-Wide Association Study|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|Glucosylceramidase|alpha-Synuclein|Age-at-Onset|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Trait, Complex|Mutation|Genes, MHC Class II 22 TMEM163 27098836 J. Comp. Neurol. 2016 10.1002/cne.24021 3 0 0 9 Animals|Mice|*Callithrix|*Claustrum|Basal Ganglia|*In Situ Hybridization|Cerebral Cortex|Corpus Striatum|Neurons|Brain|Macaques 22 TMEM163 26738859 Mol. Neurobiol. 2016 10.1007/s12035-015-9649-5 6 0 0 9 Humans|*Genome-Wide Association Study|*Parkinson Disease|*Alzheimer Disease|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Alleles|Case-Control Studies|Risk Factors|Apolipoprotein E4|GAK protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins 22 TMEM38B 27803445 Biol. Pharm. Bull. 2016 10.1248/bpb.b16-00612 4 0 0 37 Mice|Animals|*Osteogenesis Imperfecta|Calcium Signaling|Endoplasmic Reticulum|*Mutations|Genes, Recessive|Ion Channels|Calcium|*Cations|Mice, Knockout|TRIC-A protein, mouse|TRIC-B protein, mouse 25 TMEM38B 27441836 PLoS Genet. 2016 PMC4956114 10.1371/journal.pgen.1006156 13 43 1 37 *Osteogenesis Imperfecta|*Calcium|Genes, Recessive|Type I Collagen|Membrane Channel|Mutations|Collagen|*Cations|Pedigree|Osteoblasts|Extracellular Matrix|Endoplasmic Reticulum|Homeostasis 25 TMEM38B 26911354 J. Hum. Genet. 2016 10.1038/jhg.2016.11 6 0 1 37 Child|Humans|*Osteogenesis Imperfecta|Homozygote|Genes, Recessive|Phenotype|Heterozygote|Mutations|Exon|Collagen Type I|Sequencing, Next-Generation|Chinese|TMEM38B protein, human|Ion Channels 25 TMEM70 27914986 Toxicol. Lett. 2016 10.1016/j.toxlet.2016.11.022 1 0 0 63 Female|Pregnancy|Rats|Animals|*Thioacetamide|*Down-Regulation|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Cell Transformation, Neoplastic|*Carcinogenesis|Liver Neoplasms, Experimental|Carcinogens|DNA Methylation|Liver|Rats, Inbred F344|Cell Proliferation|CpG Island|Hepatocytes|Glutathione S-Transferase pi|Apoptosis|*Epigenetic|Precancerous Conditions 44 TMEM70 27504452 Front Cardiovasc Med 2016 PMC4958622 10.3389/fcvm.2016.00025 26 5 1 63 Humans|Child|Cataract and cardiomyopathy|*Cardiomyopathies|Cardiomyopathy, infantile histiocytoid|Mitochondrial Diseases|DNA, Mitochondrial|Mitochondria, Heart|Muscles, Cardiac|Arrhythmias, Cardiac|Heart Failure|Energy Metabolism|Mutations|Heart Ventricles|Barth Syndrome|Cataract|Electron Transport Complex III 44 TMEM70 26813553 Zhonghua Xin Xue Guan Bing Za Zhi 2016 10.3760/cma.j.issn.0253-3758.2016.01.011 0 0 0 63 Humans|*KCNQ1 Potassium Channel|*Cardiomyopathy, Hypertrophic|*Phenotype|*Electrocardiography|Cardiac Myosins|*Mutation|Cardiomyopathy, Hypertrophic, Familial|Myosin Heavy Chains|Pedigree|Echocardiography|Asian Continental Ancestry Group|Exons|KCNQ1 protein, human|MYH7 protein, human 44 TNP2 28005365 J. Org. Chem. 2016 10.1021/acs.joc.6b02590 2 0 0 42 Rats|Mice|Animals|Electron Paramagnetic Resonance|Trityl Compounds|Free Radicals|Oxygen|Molecular Structure|monomethoxypolyethylene glycol|Polyethylene Glycols|Tnp2 protein, mouse|Nuclear Proteins 118 TNP2 27573846 Proc. Natl. Acad. Sci. U.S.A. 2016 PMC5027415 10.1073/pnas.1611995113 10 2 0 42 Humans|Male|*RNA Precursors|Epigenesis, Genetic|*Spermatogenesis|Spermatids|*RNA Splicing|Testes|Polypyrimidine Tract-Binding Protein|Infertility, Male|Alternative Splicing|Histones|mRNA|PTBP1 protein, human|Heterogeneous-Nuclear Ribonucleoproteins 118 TNP2 26811546 Reproduction 2016 10.1530/REP-15-0403 2 0 0 42 Male|Humans|*Semen|*Lipid Peroxidation|*DNA Fragmentation|*Antioxidants|*Sperm|Semen Analysis|Semen Preservation|Glutathione Peroxidase|Sperm Motility|Catalase|Superoxide Dismutase|Oxidative Stress|Reactive Oxygen Species|Free Radicals|*Bodily Secretions|Membrane Potential, Mitochondrial 118 TONSL 27797818 EMBO J. 2016 PMC5283591 10.15252/embj.201593132 18 4 0 109 Humans|RAD51 Protein|DNA Replication|DNA Repair|DNA Breaks, Double-Stranded|BRCA2 protein, human|BRCA2 Protein|Homologous Recombination|DNA-Binding Proteins|Nuclear Proteins|DNA Damage|Cell Cycle Proteins|DNA, Single-Stranded|Replication Protein A|Recombination Repair, Homologous|NF-kappa B|Protein Binding|ds-DNA|RAD51 protein, human 28 TONSL 27506634 Sci Rep 2016 PMC4979022 10.1038/srep31109 18 7 1 109 Cattle|Animals|Female|*Milk|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|*Genotype|*Phenotype|Dairying|Genome|*Chromosome Mapping|Allele Frequency|High-Throughput Nucleotide Sequencing|docosapentaenoic acid|Fatty Acids, Unsaturated|*Base Sequence|Canada 28 TONSL 27338793 Nature 2016 PMC4939875 10.1038/nature18312 44 27 1 109 Humans|*Chromatin|Histones|DNA Repair|DNA Replication|Nuclear Proteins|DNA-Binding Proteins|Homologous Recombination|DNA Breaks, Double-Stranded|Nucleosomes|Cell Cycle Proteins|NF-kappa B|Chromatids|DNA Damage|Stability, Genome|G2 Phase|Protein Binding|HeLa Cells|TONSL protein, human 28 TOR2A 27798237 Mol. Biol. Cell 2016 PMC5156537 10.1091/mbc.E16-07-0511 19 8 0 254 Humans|*Nuclear Envelope|TOR1A protein, human|Molecular Chaperones|ATPases|Carrier Proteins|Membrane Proteins|Endoplasmic Reticulum|HSC70 Heat-Shock Proteins|Protein Binding|Mutation|HeLa Cells 64 TOR2A 27711207 PLoS ONE 2016 PMC5053442 10.1371/journal.pone.0164364 7 0 1 254 Humans|Child|*Albuminuria|*Glomerular Filtration Rate|Prospective Studies|*Anemia, Sickle Cell|APOL1 protein, human|Apolipoprotein L1|Hydroxyurea|*Blood Cell Count, White|*Modifier Gene|Lipoproteins, HDL|Genotype|Genetic Variation|CD163 antigen|Receptors, Cell Surface|Genetic Predisposition to Disease|Renal Insufficiency|Genetic Polymorphisms|Antigens, CD 64 tppp3 27390593 J Cancer 2016 PMC4934026 10.7150/jca.14790 7 21 1 109 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Tubulin|HeLa Cells|*Polymerization|*Apoptosis|Cell Proliferation|Cell Cycle|shRNA|Cell Division|Cell Line, Tumor 22 TRAK2 27737633 BMC Evol. Biol. 2016 PMC5064798 10.1186/s12862-016-0780-3 1 14 1 105 Humans|Animals|Mice|Caenorhabditis elegans|*Eutherian|Phylogeny|Dictyostelium|Transport Proteins|Neurons|Adaptor Proteins, Vesicular Transport|Mitochondrial Proteins|Mitochondria|Kinesin|Protein Transport|Promoter Regions, Genetic|RNA, Small Interfering|Vertebrate|*Intestine|Trak1 protein, mouse 46 TRAK2 27414745 Clin. Genet. 2016 10.1111/cge.12831 10 1 0 105 Humans|Infant, Newborn|Spastic paraplegia 10, autosomal dominant|Spastic Paraplegia, Hereditary|KIF11 protein, human|Kinesin|*Epilepsies, Myoclonic|Pedigree|Mutations|Sequencing, Whole Exome|*Myoclonic Seizures|Phenotype|*Leukoencephalopathies|Mutations, Missense|KIF5A protein, human 46 TSHZ1 27766118 Mol Cytogenet 2016 PMC5057431 10.1186/s13039-016-0285-1 2 1 1 48 Chromosome Deletion|Phenotype|Abnormalities, Multiple|Karyotyping|Intellectual Disability|Chromosome Mapping|Syndrome 42 TSHZ1 27521061 Gene Expr. Patterns 2016 10.1016/j.gep.2016.08.001 0 0 0 48 Mice|Animals|*Genes, Homeobox|*Vomeronasal Organ|In Situ Hybridization, Fluorescence|*Mice, Inbred C57BL|proto-oncogene protein Pbx3|Proteins, Homeo Domain|LIM-Homeodomain Proteins|Transcription Factors|Cell Differentiation|Olfactory Mucosa|Repressor Proteins|Gene Expression Regulation, Developmental|Olfactory Bulb|Stem Cells|Myeloid Ecotropic Viral Integration Site 1 Protein|Neurons|Zfhx3 protein, mouse|Lhx2 protein, mouse 42 TSHZ1 27243442 J. Comp. Neurol. 2016 10.1002/cne.24051 4 0 0 48 Mice|Animals|*Genes, Homeobox|*Olfactory Epithelium|Transcription Factor|Homeodomain Proteins|Receptors, Odorant|*Smell|Olfactory Bulb|Myeloid Ecotropic Viral Integration Site 1 Protein|In Situ Hybridization|Nasal Cavity|Guanylate Cyclase 42 TSHZ1 27060316 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2016 10.3760/cma.j.issn.1003-9406.2016.02.017 0 0 0 48 Humans|Chromosome 18 deletion syndrome|*Chromosome Disorders|*Chromosome Deletion|*Chromosomes, Human, Pair 18|*Microarray Analysis|Phenotype|Genotype|Syndrome 42 TSPY1 27771326 J Genet Genomics 2016 10.1016/j.jgg.2016.09.003 2 1 0 100 Humans|Male|Female|*Testis|*DNA Methylation|Germ Cell Tumor|Gonadoblastoma|*Genes, Neoplasm|Cell Cycle Proteins|*Gene Expression|Testicular Neoplasms|DNA-Binding Proteins|Hepatocellular Carcinoma|Chromosomes, Human, Y|Liver Cancer|Oncogenesis|Germ Cells|Genes, Regulator|Ovarian Neoplasms|DNA 125 TSPY1 26793590 Urol Case Rep 2016 PMC4719899 10.1016/j.eucr.2015.12.003 0 0 1 100 Child|Humans|Adolescent|*Ovotesticular Disorders of Sex Development|*Karyotyping|*Karyotype|*Sex Development|Mosaicism|Ambiguous Genitalia|Chromosomes, Human, Y|*Gonadectomy 125 TSPY1 26790664 Mol Diagn Ther 2016 10.1007/s40291-015-0184-x 2 0 0 100 Pregnancy|Humans|Female|*Endoglin|*Pre-Eclampsia|*Cohort Studies|*Cell Free DNA|*Fetus|*Prenatal Care|Antigens, CD|*Genetic Testing|Biomarkers|Blood Pressure|DNA|Egypt 125 TTI2 27935167 Genes Cells 2016 10.1111/gtc.12454 3 7 0 57 Animals|*Schizosaccharomyces|*Signal Transduction|Schizosaccharomyces pombe Proteins|Telomere-Binding Proteins|prefoldin|Molecular Chaperones|Casein Kinase II|Phosphorylation|Saccharomyces cerevisiae Proteins|HSP90 Heat-Shock Proteins|Intracellular Signaling Peptides and Proteins|Protein Binding 25 TTI2 27899648 Nucleic Acids Res. 2016 PMC5389508 10.1093/nar/gkw1021 13 2 0 57 *Saccharomyces cerevisiae|*Selection, Genetic|tRNAPro|*Molecular Chaperones|*Yeast, Dried|Saccharomyces cerevisiae Proteins|Suppressor Mutation|prolyl T RNA synthetase|Amino Acyl-tRNA Synthetases|Mutation|Aminoacylations|Allele 25 TTI2 27172216 G3 (Bethesda) 2016 PMC4889661 10.1534/g3.116.029520 8 15 1 57 Humans|*Saccharomyces cerevisiae|*Phosphatidylinositol 3-Kinase|Saccharomyces cerevisiae Proteins|Molecular Chaperones|Telomere-Binding Proteins|HSP90 Heat-Shock Proteins|transformation-transcription domain-associated protein|Nuclear Proteins|MTOR protein, human|TOR Serine-Threonine Kinases|Protein Binding|Adaptor Proteins, Signal Transducing|Heat Shock Proteins|Signal Transduction|Tel2 protein, S cerevisiae|Tti2 protein, S cerevisiae 25 TTI2 27132593 Am. J. Hum. Genet. 2016 PMC4863664 10.1016/j.ajhg.2016.03.014 10 5 1 57 Humans|*Intellectual Disability|Molecular Chaperones|Telomere-Binding Proteins|Saccharomyces cerevisiae Proteins|Ataxia Telangiectasia Mutated Proteins|Signal Transduction|Protein Kinases|Protein Binding 25 TTI2 26833729 Genes Dev. 2016 PMC4743059 10.1101/gad.271445.115 9 3 1 57 Humans|*Transcription Factor|*Tumor Suppressor Protein p53|*Genes, Homeobox|*Gain of Function Mutation|*Signal Transduction|*DNA-Binding Proteins|Cell Senescence|Ataxia Telangiectasia Mutated Proteins|*Gene Expression Regulation|*Aging|Cell Cycle|DNA Damage|HCT116 Cells|Ten1 protein, human|Telomere-Binding Proteins|Stn1 protein, human|ATM protein, human 25 TWSG1 26829466 Matrix Biol. 2016 PMC5080453 10.1016/j.matbio.2016.01.019 3 43 1 895 Humans|Animals|*Gastrulation|chordin|Intercellular Signaling Peptides and Proteins|Glycoproteins|Bone Morphogenetic Protein|*Signal Transduction|BMP4 protein, human|Bone Morphogenetic Protein 4|Gastrula|Protein Binding|Carrier Proteins|*Gene Expression Regulation|Zebrafish|Drosophila Proteins 47 TWSG1 27698904 J Cancer 2016 PMC5039388 10.7150/jca.15423 8 3 1 895 Humans|*DNA Methylation|CpG Islands|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|Epigenesis, Genetic|Genome, Human|Epigenetic|High-Throughput Nucleotide Sequencing|Promoter Regions, Genetic|Sequence Analysis, DNA|Immunoprecipitation|Gene Expression Profiling|Gene Ontology|*Genetic Profile|Cell Line, Tumor|*Biochemical Phenomena|RNA, Messenger 47 TWSG1 26743476 Mod. Pathol. 2016 10.1038/modpathol.2015.150 5 2 1 895 *Cell Transdifferentiation|Gastric Mucosa|*Stomach|Metaplasia|Gastric Cancer|CDX2 Transcription Factor|Helicobacter pylori|Homeodomain Proteins|Precancerous Conditions|Transcription Factors|SOXB1 Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Transformation, Neoplastic|Cell Nucleus|Promoter Regions, Genetic|Intestinal Mucosa|*Upper Gastrointestinal Tract 47 UBAP2L 27456362 Tumour Biol. 2016 10.1007/s13277-016-5159-y 5 4 0 157 Humans|*Apoptosis|*Colorectal Carcinoma|Cell Proliferation|Cell Cycle Arrest|HCT116 Cell|Cell Cycle|RNA Interference|CASP3 protein, human|Caspase 3|RNA, Small Interfering|Cell Movement|Cell Line, Tumor|Gene Knockdown Techniques|Apoptosis Regulatory Proteins|Signal Transduction|Gene Expression Regulation, Neoplastic|Carrier Proteins|Lentivirus 21 UBAP2L 27121050 Oncotarget 2016 PMC5078065 10.18632/oncotarget.8783 9 20 1 157 Humans|*Carcinoma, Hepatocellular|*Annexin A2|*Liver Neoplasms|*Ubiquitination|Prognosis|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Proliferation|Hep G2 Cells|Cell Movement|Apoptosis|*Neoplastic Processes|Downregulation 21 ULK4 27980663 BMC Proc 2016 PMC5133474 10.1186/s12919-016-0057-2 8 0 1 17 *Haplotypes|Models, Genetic|Genetic Association Studies|Bayes Theorem|Case-Control Studies|Polymorphism, Single Nucleotide|Genetic Variation|Computer Simulation 27 ULK4 27736895 PLoS ONE 2016 PMC5063457 10.1371/journal.pone.0164132 10 5 1 17 Humans|*African Americans|*Blood Pressure|*Hispanic|*Genetic Loci|*Blood Pressure Determination|Genome-Wide Association Study|Hypertension|*Phenotype|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Hyperaldosteronism, Primary|Genotype|Systole|Ethnic Groups 27 ULK4 27670918 Sci Rep 2016 PMC5037360 10.1038/srep31126 6 17 1 17 Animals|*Risk Factors|*Schizophrenia|*Neurogenesis|Neurite|Protein-Serine-Threonine Kinases|Disease Models, Animal|Brain|Cell Proliferation 27 ULK4 27587788 Cancer Epidemiol. Biomarkers Prev. 2016 PMC5524541 10.1158/1055-9965.EPI-15-1193 7 2 0 17 Humans|Genome-Wide Association Study|*Multiple Myeloma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|European Continental Ancestry Group|African Continental Ancestry Group|Case-Control Studies 27 ULK4 27569546 Am. J. Hum. Genet. 2016 PMC5011062 10.1016/j.ajhg.2016.06.034 13 0 0 17 Humans|Genome-Wide Association Study|*Aneurysm, Dissecting|Thoracic Aortic Aneurysms|Fibrillin-1|Marfan Syndrome|SNPs|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|Pedigree|Mutations|Fibrillins|Aorta|DNA Copy Number Variations|Microfilament Proteins|LRP1 protein, human|Low Density Lipoprotein Receptor-Related Protein-1|Ulk4 protein, human 27 ULK4 27445138 J. Neurosci. 2016 PMC6705555 10.1523/JNEUROSCI.0621-16.2016 7 1 0 17 Mice|Animals|Ciliopathies|Cilia|Cerebral Ventricles|Ependyma|Cerebral Aqueduct|Hydrocephalus|Protein-Serine-Threonine Kinases|Animals, Newborn|Signal Transduction|Protein Transport|Disease Models, Animal|Gene Expression Regulation|FOXJ1 protein, mouse|Forkhead Transcription Factors 27 ULK4 27300315 Stem Cells 2016 10.1002/stem.2423 6 0 1 17 Humans|Mice|Animals|*Neural Stem Cell|Neurogenesis|Protein-Serine-Threonine Kinases|Cerebral Cortex|Cell Cycle|Neurons|Signal Transduction|Cell Proliferation|Phases, G2|Ulk4 protein, human 27 ULK4 26956052 Oncotarget 2016 PMC4991443 10.18632/oncotarget.7917 20 7 1 17 Humans|*Glioblastoma|*Prognosis|Phosphatidylinositol 3-Kinases|Neoplasm Recurrence, Local|Temozolomide|Brain Neoplasms|Antineoplastic Agents, Alkylating|Cancer Biomarkers|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Cell Proliferation|LATS2 protein, human|Tumor Suppressor Proteins|Drug Resistance, Neoplasm|Apoptosis|Xenograft Model Antitumor Assays|Genes, Regulator|Protein-Serine-Threonine Kinases 27 UPK1A 27232948 Am. J. Transplant. 2016 10.1111/ajt.13891 4 0 0 118 *Kidney Transplantation|*mRNA|Reproducibility of Results|Case-Control Studies|*Kidney|Graft Rejection|Transplantation, Homologous|RNA, Ribosomal, 18S|ROC Curve|Biomarkers|*Urinary Tract|Biopsy 66 UPK2 27687590 Oncotarget 2016 PMC5342114 10.18632/oncotarget.12324 0 4 0 81 Humans|*Adenovirus|*Urinary Bladder Neoplasms|Thymidine Kinase|Genes, Transgenic, Suicide|Gene Therapy|Ganciclovir|*Adenoviridae Infections|Genetic Vectors|Coxsackie Adenovirus Receptor|*Bladder|Simplexvirus|Apoptosis|Cell Line, Tumor|Promoter Regions, Genetic 124 UPK2 27594510 Pathology 2016 10.1016/j.pathol.2016.05.008 2 0 0 81 Humans|*Uroplakin II|Neoplasm Recurrence, Local|*Carcinoma, Transitional Cell|GATA3 protein, human|*GATA3 Transcription Factor|*Urologic Neoplasms|Urinary Bladder Neoplasms|Urothelium|Immunohistochemistry|*Prognosis|Biomarkers, Tumor|Tissue Array Analysis|Diagnosis, Differential 124 UPK2 27234646 Basic Clin. Pharmacol. Toxicol. 2016 10.1111/bcpt.12627 3 1 0 81 Mice|Animals|*Uroplakin II|*Urinary Bladder|S-allylcysteine|*Down-Regulation|*Urothelium|*Cyclophosphamide|Cystitis|*Cysteine|Mesna|Antineoplastic Agents, Alkylating|Antineoplastic Agents|Protective Agents|Antioxidants|Hemorrhage|Alkylating Agents|Free Radicals 124 UPK2 26992222 Oncotarget 2016 PMC5029676 10.18632/oncotarget.8114 9 8 1 81 Humans|Mice|Animals|*Pyruvate Kinase|*Isoenzymes|*Cell Transformation, Neoplastic|*Urothelium|Thyroid Hormones|Cell Proliferation|*Tumorigenesis|Carrier Proteins|Membrane Proteins|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Carcinoma, Transitional Cell|Urinary Bladder Neoplasms|Cell Line, Tumor|Carcinoma, Papillary|Apoptosis|Signal Transduction|Phosphorylation 124 UPK2 26988609 Eur. Urol. 2016 PMC5804336 10.1016/j.eururo.2016.02.056 20 1 0 81 *Urinary Bladder Neoplasms|*Transcriptome|Carcinoma, Transitional Cell|Bladder|Prognosis|Biomarkers, Tumor|Gene Expression Profiling|*Microarray Analysis 124 URAD 27413216 J Food Sci Technol 2016 PMC4926902 10.1007/s13197-015-2123-6 0 0 0 3 *Solanum tuberosum|*Legume|Phenols|Flour|Antioxidants|Ascorbic Acid|Vegetables 55 URAD 27378513 Presse Med 2016 10.1016/j.lpm.2016.05.011 2 0 0 3 *Anesthetics, Local|Drug Hypersensitivity|Skin Tests|Preservatives, Pharmaceutical|Epinephrine 55 USP29 27901122 Sci Rep 2016 PMC5128876 10.1038/srep38136 8 2 0 22 Male|Animals|Mice|*Mice, Inbred ICR|Genomic Imprinting|Kruppel-Like Transcription Factors|DNA Methylation|Alleles|Ubiquitin-Specific Proteases|Mutation|Peg3 protein, mouse 34 USP29 27327533 PLoS ONE 2016 PMC4915674 10.1371/journal.pone.0158004 2 3 1 22 Male|Female|Genomic Imprinting|DNA Methylation|Kruppel-Like Transcription Factors|Ubiquitin-Specific Proteases|Allele|Promoter Regions, Genetic|Gene Expression|Endopeptidases 34 VAX2 27633992 Development 2016 10.1242/dev.134601 0 0 0 24 Animals|Mice|*Retina|Body Patterning|Retinal Pigment Epithelium|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Bone Morphogenetic Protein 4|PAX2 Transcription Factor|Wnt Signaling Pathway 164 VAX2 27179412 Exp. Eye Res. 2016 10.1016/j.exer.2016.05.008 0 0 0 24 Animals|Humans|Prospective Studies|*Retina|Photoreceptors, Cone|Homeodomain Proteins|Transcription Factor|*Primate|Protein Isoforms|Gene Expression Regulation, Developmental|Cytoplasm|VAX2 protein, human 164 VAX2 26929985 Epigenetics 2016 PMC4854556 10.1080/15592294.2016.1154246 11 0 0 24 *Urinary Bladder Neoplasms|Neoplasm Recurrence, Local|DNA Methylation|Carcinoma, Transitional Cell|PRRX1 protein, human|Homeodomain Proteins|Promoter Regions, Genetic|Prognosis|CpG Islands|STAT5A protein, human|Tumor Suppressor Proteins|Biomarkers, Tumor|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Bladder|Disease Progression|STAT5 Transcription Factor 164 VIPAS39 27319744 J. Pathol. 2016 10.1002/path.4762 5 2 0 57 Mice|Animals|Humans|*Megakaryocytes|HEK293 Cells|*Protein Transport|Platelets|Arthrogryposis|Cytoplasmic Granules|Vesicular Transport Proteins|von Willebrand Factor|Cholestasis|Mice, Knockout|Great Britain|Ireland|VPS33B protein, human|Sec22b protein, mouse|R-SNARE Proteins|VPS33B protein, mouse 24 VIPAS39 26971401 Am. J. Hematol. 2016 10.1002/ajh.24359 3 0 0 57 *Blood Platelets|Gray Platelet Syndrome|Megakaryocytes|Arthrogryposis renal dysfunction cholestasis syndrome|Arthrogryposis|Cytoplasmic Granules|Platelet Aggregation|Cholestasis|Renal Insufficiency|Mutations|Proteins|Bleeding 24 VIPAS39 26808426 Eur J Med Genet 2016 10.1016/j.ejmg.2016.01.005 0 0 0 57 Infant|Humans|Male|Arthrogryposis renal dysfunction cholestasis syndrome|*Arthrogryposis|Cholestasis|*Intrahepatic Cholestasis|Renal Insufficiency|Vesicular Transport Proteins|Renal Tubular Acidosis|Mutation|Homozygote|Phenotype|*Syndromes|*Kidney Diseases|VIPAS39 protein, human 24 VSX1 28003732 Mol. Vis. 2016 PMC5166794 1 9 0 45 Animals|*Transcriptional Regulatory Element|*Photoreceptor Cells|Genes, Homeobox|Eye Proteins|Homeodomain Proteins|Xenopus Proteins|Xenopus laevis|Gene Expression Regulation, Developmental|Transcription Factors|Retina|Conserved Sequence|Zebrafish|Amino Acid Sequence|Promoter Regions, Genetic|Transcription, Genetic 115 VSX1 27819732 Genet. Mol. Res. 2016 10.4238/gmr15049024 3 0 0 45 Humans|*Keratoconus|*Genes, Homeobox|Eye Proteins|Homeodomain Proteins|Mutations|Exon|Mutations, Missense|Base Sequence|Polymerase Chain Reaction 115 WFDC1 27827323 Hum. Reprod. 2016 10.1093/humrep/dew267 4 0 0 69 Humans|Male|*Semen|*Infertility, Male|Sperm Motility|Semen Analysis|Spermatozoa|Spermatogenesis|*Kallikreins|*Bodily Secretions|*Phenotypes|*Body Fluids 42 WFDC1 28955923 Biochem Biophys Rep 2016 PMC5613349 10.1016/j.bbrep.2016.06.010 1 23 0 69 Humans|Male|*Prostate|*Cathepsin L|*Cathepsin B|Prostatic Neoplasms|FN1 protein, human|Fibronectin|*Transglutaminases|Disulfides|Wound Healing|WFDC1 protein, human|Proteins 42 WFDC1 27115470 Br. J. Cancer 2016 PMC4891514 10.1038/bjc.2016.91 2 10 0 69 Humans|Male|*Prostate|*Cyclooxygenase 2|*Cells, Stromal|Prostate Cancer|WFDC1 protein, human|*Apoptosis|Cell Line, Tumor|*Isoforms|Paracrine Communication|Gene Expression Regulation, Neoplastic|Culture Media, Conditioned|PTGS2 protein, human 42 WFDC1 26780319 Invest. Ophthalmol. Vis. Sci. 2016 10.1167/iovs.15-17610 1 2 0 69 Mice|Animals|*Induced Pluripotent Stem Cells|Cell Differentiation|Cells, Cultured|Epithelial Cells|*Epithelium 42 WHAMM 27723370 Autophagy 2016 PMC5173263 10.1080/15548627.2016.1236877 6 0 0 1784 *Autophagosomes|*Actins|Actin-Related Protein 2-3 Complex|Actin Cytoskeleton|Microtubule-Associated Proteins|Autophagy|Membrane Proteins 33 WHAMM 27068179 Trends Biochem. Sci. 2016 PMC4884163 10.1016/j.tibs.2016.03.004 41 15 2 1784 Animals|*Actins|*Wasp|WAS protein, human|*Wiskott-Aldrich Syndrome Protein|Actin Cytoskeleton|Microfilament Proteins|Profilin|Arp2-3 Complex|Protein Structure, Tertiary|Protein Binding|Drosophila Proteins|Formins|Amino Acid Sequence|Models, Molecular 33 WHAMM 26823012 Mol. Biol. Cell 2016 PMC4791140 10.1091/mbc.E15-07-0508 9 26 1 1784 *Actins|Arp2-3 Complex|Microtubules|Cytoskeleton|Microtubule-Associated Proteins|Membrane Proteins|Plasma Membrane|*Membrane|Cell Movement 33 XIRP2 27717584 Parkinsonism Relat. Disord. 2016 10.1016/j.parkreldis.2016.09.028 13 7 0 38 Humans|*Parkinson Disease|*MicroRNAs|*Gyrus Cinguli|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|alpha-Synuclein|*Parkinsonian Disorders|Protein-Serine-Threonine Kinases|Ubiquitin-Protein Ligases|Genetic Predisposition to Disease|Protein Kinases|Mutation|SNCA protein, human|LRRK2 protein, human 42 XIRP2 27639425 Exp. Cell Res. 2016 10.1016/j.yexcr.2016.09.008 2 2 0 38 Mice|Animals|*Sarcomeres|*Mice, Knockout|*Cardiac Hypertrophy|*Myocardium|Hypertrophy, Left Ventricular|FLNC protein, human|Filamin C|Myocytes, Cardiac|GJA1 protein, human|Connexin43|Nuclear Proteins|DNA-Binding Proteins|Skeletal Muscles|Muscle Contraction|Arrhythmias, Cardiac 42 XIRP2 27206985 Hum. Mol. Genet. 2016 10.1093/hmg/ddw135 9 1 0 38 Mice|Animals|FLNC protein, human|*Filamins|Myofibrils|Myofibrillar Myopathy|Myopathies, Structural, Congenital|Sarcomeres|Nuclear Proteins|Skeletal Muscles|DNA-Binding Proteins|Cytoskeletal Proteins|Actins|Cardiomyocytes|Mutations 42 XIRP2 26857262 Cancer Res. 2016 10.1158/0008-5472.CAN-15-2443 37 0 3 38 Humans|*Prognosis|*Stomach Neoplasms|CDH1 protein, human|Cadherins|Mutation|Antigens, CD|Sequencing, Next-Generation|Genetic Predisposition to Disease 42 XPO4 27462267 Front Aging Neurosci 2016 PMC4941795 10.3389/fnagi.2016.00171 3 14 1 139 Humans|*Apo E-4|*Alzheimer Disease|*Heterozygote|Apolipoproteins E|Gene Frequency|Genotype|Alleles|Polymorphism, Genetic|Genetic Predisposition to Disease|Parkinson Disease|Risk Factors|Apo E-3|Xpo4 protein, human|Karyopherins|RASD2 protein, human|GTP-Binding Proteins|RIN1 protein, human|Intracellular Signaling Peptides and Proteins 35 XPO4 27451718 J Nanosci Nanotechnol 2016 10.1166/jnn.2016.11885 1 0 0 139 *Luminescence|*Powders|Europium|Luminescent Measurements|Nanostructures|Xray Diffraction|Microscopy, Electron, Scanning 35 XPO4 27306458 Nat Commun 2016 PMC4912631 10.1038/ncomms11952 9 8 1 139 hypusine|*Lysine|Peptide Initiation Factors|Karyopherins|Binding Site|Export, Nuclear|Amino Acid Sequence|Receptors, Cytoplasmic and Nuclear|Protein Binding|RNA-Binding Proteins|Cloning, Molecular|Cell Nucleus|Sequence Homology, Amino Acid|Sequence Alignment|Models, Molecular 35 XPO4 28773483 Materials (Basel) 2016 PMC5503088 10.3390/ma9050356 1 1 0 139 Luminescence|Luminescent Measurements 35 YBEY 28031281 J. Bacteriol. 2016 PMC5309912 10.1128/JB.00798-16 2 1 0 103 37 YBEY 27834201 mBio 2016 PMC5101352 10.1128/mBio.01785-16 15 26 1 103 *Escherichia coli|*RNA, Ribosomal, 16S|Escherichia coli Proteins|Ribosome|ribosomal protein S11|Ribosomal Proteins|RNA, Bacterial|Gene Expression Regulation, Bacterial|RNA, Ribosomal|Endoribonucleases|Metalloproteins|GTPases|RNA 3' End Processing|YbeY protein, E coli 37 YBX2 27929740 Cell Cycle 2016 PMC5324759 10.1080/15384101.2016.1261225 3 0 0 47 *mRNA|*Oocyte|Embryo, Mammalian|Ribosomes|RNA Binding Protein|*Cytosol|Protein-Arginine Deiminases|Hydrolases 92 YBX2 27611906 PLoS ONE 2016 PMC5017692 10.1371/journal.pone.0162722 7 6 1 47 Female|Animals|Mice|*Histones|*Methylation|*Oocytes|Ovulation|*Aging|Ovarian Follicle|Oogenesis|Spindle Apparatus|Cellular Senescence|*Protein Processing, Post-Translational|Ybx2 protein, mouse|RNA-Binding Proteins 92 YBX2 27492081 Reproduction 2016 10.1530/REP-16-0155 1 1 0 47 Female|Cattle|Animals|*Stem Cell Factor|*Oogenesis|Cumulus Cells|Oocytes|In Vitro Oocyte Maturation Techniques|Meiosis|Blastocyst|Natriuretic Peptide, C-Type|Fertilization in Vitro|Embryonic Development|Culture Media 92 ZBED3 27551309 Genes Nutr 2016 PMC4968454 10.1186/s12263-016-0524-4 7 7 1 98 *Diabetes Mellitus, Type 2|*Incidence|*Wnt Signaling Pathway|Transcription Factor 7-Like 2 Protein|*Dietary Fiber|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Transcription Factor 21 ZC3H12D 27472830 J. 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Biochem. 2016 10.1002/jcb.25665 5 0 0 498 In Situ Hybridization, Fluorescence|RNase|RNA Stability|3' UTR|*Inflammation|mRNA|Interleukin 6|Transcription Factors|Immunoprecipitation|Cytokines|Reporter Gene 20 ZC3H12D 27010659 Forensic Sci Int Genet 2016 10.1016/j.fsigen.2016.01.017 2 0 1 498 Humans|*Semen|*Saliva|*DNA Methylation|*Epigenetic|*Markers, DNA|CpG Islands|*Body Fluids|Forensic Genetics|hydrogen sulfite|Sulfites|*Bodily Secretions|Sequence Analysis, DNA|DNA|Epigenesis, Genetic 20 ZC3H12D 26819418 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2016 10.11817/j.issn.1672-7347.2016.01.001 0 0 0 498 *Neutrophils|*Factor B|*Signal Transduction|Mucin 5AC|NF-kappa B|Epithelial Cells|Bronchi|Lipopolysaccharides|Phosphorylation 20 ZC3H14 27868086 RNA Dis 2016 PMC5113822 4 4 0 116 *mRNA|*Intellectual Disability|RNA-Binding Proteins|*RNA Splicing|Polyadenylation|Cell Nucleus|Drosophila Proteins|Nuclear Proteins|Gene Expression Regulation|Conserved Sequence|*Quality Control 23 ZC3H14 27563065 J. Biol. Chem. 2016 PMC5077184 10.1074/jbc.M116.754069 7 2 0 116 *mRNA|polyadenosine|*RNA Precursors|*RNA Binding Protein|*Adenosine|*Polymers|Polyadenylation|Nuclear Proteins|Cell Nucleus|*Gene Expression|Zinc Fingers|Adenosine Triphosphate 23 ZC3H14 27528618 Mol. Cell. Biol. 2016 PMC5064217 10.1128/MCB.00402-16 11 2 0 116 *RNA Precursors|polyadenosine|Proteomics|*RNA Binding Protein|*Adenosine|*Polymers|*RNA Splicing|Nucleocytoplasmic Transport Proteins|mRNA|RNA Exosome|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Cell Nucleus|Nuclear Proteins|NAB2 protein, S cerevisiae|MUD2 protein, S cerevisiae|Splicing Factor U2AF 23 ZC3H14 27049816 Transcription 2016 PMC4984684 10.1080/21541264.2016.1170252 0 15 1 116 *RNA Polymerase III|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Nucleocytoplasmic Transport Proteins|RNA, Fungal|RNA Polymerase B|RNA-Binding Proteins|RNA, Messenger|Protein Binding|NAB2 protein, S cerevisiae 23 ZC3H14 27012031 Clin. Lab. 2016 10.7754/clin.lab.2015.150517 0 0 0 116 Humans|Female|Pregnancy|*Multiplex Polymerase Chain Reaction|*Intellectual Disability|Iran|*Genes, Recessive|Allele Frequency|Microsatellite Repeats|Homozygote|Allele|Heterozygote|Asian Continental Ancestry Group 23 ZDHHC9 27747153 Neuroimage Clin 2016 PMC5053034 10.1016/j.nicl.2016.07.016 4 0 1 61 Humans|Child|*Intellectual Disability|*Epilepsy|Brain|White Matter|Diffusion Tensor Imaging|Cognition Disorders|Magnetic Resonance Imaging|Language|Neuropsychological Tests|Neurodevelopmental Disorders|Language Development Disorders 30 ZDHHC9 27481942 J. Biol. Chem. 2016 PMC5025705 10.1074/jbc.M116.725762 14 0 0 61 Humans|*Lipoylation|Protein Transport|Golgi Complex|Receptors, Adrenergic, beta-2|*Cytoplasm|Plasma Membrane|Phosphorylation|cAMP Dependent Protein Kinase|Membrane Proteins|Protein Processing, Post-Translational|Carrier Proteins|ZDHHC9 protein, human|Acyltransferases 30 zfhx4 27711207 PLoS ONE 2016 PMC5053442 10.1371/journal.pone.0164364 7 0 1 66 Humans|Child|*Albuminuria|*Glomerular Filtration Rate|Prospective Studies|*Anemia, Sickle Cell|APOL1 protein, human|Apolipoprotein L1|Hydroxyurea|*Blood Cell Count, White|*Modifier Gene|Lipoproteins, HDL|Genotype|Genetic Variation|CD163 antigen|Receptors, Cell Surface|Genetic Predisposition to Disease|Renal Insufficiency|Genetic Polymorphisms|Antigens, CD 26 zfhx4 27378168 Am. J. Med. Genet. A 2016 PMC5119633 10.1002/ajmg.a.37840 3 0 1 66 Humans|Peters anomaly|DNA Copy Number Variations|*Corneal Opacity|Anterior segment mesenchymal dysgenesis|*Eye Abnormalities|*Anterior Eye Segment|Sclerocornea|Corneal Diseases|Cornea|Microphthalmia|Lens, Crystalline|Phenotypes|*Syndromes|Intellectual Disability 26 ZNF185 27768594 Oncotarget 2016 PMC5356706 10.18632/oncotarget.12751 2 15 0 64 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|hepatitis B virus X protein|*Trans-Activators|Hepatitis B virus|Hepatitis B|Promoter Regions, Genetic|Hep G2 Cells|Liver|DNA Methylation|Cell Proliferation|Up-Regulation|Transcription Factors|*Cell Line|RNA, Messenger|DAB2IP protein, human|ras GTPase-Activating Proteins 24 ZNF185 27667456 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2016 0 0 0 64 Mice|Male|Animals|*Leydig Cells|*Sertoli Cells|*Testis|*Spermatozoa|Luteinizing Hormone|mRNA|Fluorescent Antibody Technique|Western Blotting|Cytoplasm|Zinc Fingers|ZNF185 protein, mouse|LIM Domain Proteins 24 ZNF185 27655485 J. 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Agents 2016 3 4 0 64 Humans|*Glycogen Synthase Kinase 3|*Proto-Oncogene Proteins c-akt|*Lung Adenocarcinoma|Neoplasm Invasiveness|Adenocarcinoma|Cell Proliferation|Lung Neoplasms|Signal Transduction|Gene Expression Regulation, Neoplastic|Matrix Metalloproteinase 9|Lymphatic Metastasis|Cell Line, Tumor|Proliferating Cell Nuclear Antigen|*Neoplastic Processes|ZNF185 protein, human|Cytoskeletal Proteins|LIM Domain Proteins 24 ZNF365 27432265 Breast Cancer 2016 10.1007/s12282-016-0712-5 1 1 0 33 Humans|Female|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Estrogen Receptor alpha|Alleles|Genotype|Case-Control Studies|SGSM3 protein, human|Intracellular Signaling Peptides and Proteins 57 ZNF365 27333658 Nihon Shinkei Seishin Yakurigaku Zasshi 2016 0 6 0 33 Animals|Mice|*Phosphorylation|*Neurites|Glycogen Synthase Kinase 3|*Classical Lissencephalies and Subcortical Band Heterotopias|*Neurogenesis|zinc-binding protein|Carrier Proteins|*Biological Transport|Neurons|1-Alkyl-2-acetylglycerophosphocholine Esterase|Microtubule-Associated Proteins|Nerve Tissue Proteins|Cell Migration|*Cytoplasm|Microtubule|*Learning|*Orientation, Spatial|*Cell Cycle 57 ZNF644 27546533 Stem Cell Reports 2016 PMC5031922 10.1016/j.stemcr.2016.06.012 4 16 1 140 Animals|Histocompatibility Antigens|*Neurogenesis|Histone-Lysine N-Methyltransferase|Methylation|Histones|*Gene Expression|Cell Differentiation|Zinc Finger|Gene Silencing|Cell Line, Tumor|Protein Processing, Post-Translational|Zebrafish 20 ZNF644 27034204 Eye (Lond) 2016 PMC4941079 10.1038/eye.2016.8 7 0 0 140 Humans|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genotype|Genetic Predisposition to Disease|Genotyping Techniques|Gene Frequency|Myopia, Degenerative|Haplotype|Case-Control Studies|Odds Ratio|ZNF644 protein, human|Transcription Factors|GRM6 protein, human|Receptors, Glutamate 20 ZPBP2 27848966 Nat Commun 2016 PMC5116091 10.1038/ncomms13426 26 7 0 22 *Interleukin-2|*T Cells|*Asthma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Alleles|Membrane Proteins|Gene Expression|Neoplasm Proteins|Regulatory Sequences, Nucleic Acid|Case-Control Studies 39 ZPBP2 27835674 PLoS ONE 2016 PMC5106028 10.1371/journal.pone.0166414 2 9 0 22 Humans|*Lymphocyte Activation|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Haplotypes|Alleles|Asthma|Genome-Wide Association Study|Membrane Proteins|Neoplasm Proteins|Promoter Regions, Genetic|Phenotype|Case-Control Studies|Chromosomes 39 ZPBP2 27163155 Hum. Immunol. 2016 10.1016/j.humimm.2016.05.003 2 4 0 22 Adult|Humans|Child|*Haplotypes|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asthma|Hypersensitivity, Immediate|*Chromosome 1|Phenotypes|Genotype|Genome-Wide Association Study|Case-Control Studies|Immunoglobulin E|*Chromosome Structures|Slovenia|GSDMA protein, human|Neoplasm Proteins 39 ZPBP2 27130862 J. Allergy Clin. Immunol. 2016 10.1016/j.jaci.2016.03.018 8 0 0 22 *Asthma|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Genetic Variation|Case-Control Studies|Membrane Proteins|Neoplasm Proteins 39 ZPBP2 26771610 Int J Mol Sci 2016 PMC4730340 10.3390/ijms17010098 6 2 1 22 Male|Mice|Animals|*Galactose|*Aging|Lipid Peroxidation|Spermatogenesis|Testis|Superoxide Dismutase|Malondialdehyde|Oxidative Stress|Antioxidants|*Disease Models, Animal|Mice, Inbred C57BL|*Reproduction|Sperm|Liver|Brain 39 ABCF2 26708806 Prostate 2015 10.1002/pros.23137 7 0 0 143 Humans|Male|*Prostate Cancer|ABCB6 protein, human|*Transporters, ABC|Prostate|*Disease Progression|Gene Expression Regulation, Neoplastic|Neoplasm Recurrence, Local|multidrug resistance-associated protein 2|Multidrug Resistance-Associated Proteins|Biomarkers, Tumor|Gene Expression Profiling|multidrug resistance-associated protein 1|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B 33 abhd2 25880496 PLoS ONE 2015 PMC4399978 10.1371/journal.pone.0123929 1 0 1 142 Humans|*Asian Continental Ancestry Group|*Chronic Obstructive Pulmonary Disease|Forced Expiratory Volume|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Genotype|Respiratory Function Tests|Forced Vital Capacity|Lung|Phenotype|Case-Control Studies|Smoking|ABHD2 protein, human|Hydrolases 30 ABI3BP 26359667 PLoS ONE 2015 PMC4567271 10.1371/journal.pone.0137551 6 12 1 65 *RNA, Micro|*Computational Biology|*Rheumatoid Arthritis|Gene Regulatory Networks|mRNA|Gene Expression Profiling|Gene Ontology|Oligonucleotide Array Sequence Analysis|Profile, Gene Expression|Sequencing, RNA|Gene Expression Regulation|Genetic Markers 27 ABI3BP 25631615 Genet. Epidemiol. 2015 PMC4480365 10.1002/gepi.21886 26 3 2 65 Humans|*Optic Disk|*Genome-Wide Association Study|Optic Neuropathy|Glaucoma|Glaucoma, Primary Open Angle|Nerve Fibers|Retinal Ganglion Cells|Nerve, Optic|Asian|Polymorphism, Single Nucleotide|EFEMP1 protein, human|Extracellular Matrix Proteins|KPNB1 protein, human|beta Karyopherins|TRIB2 protein, human|Calcium-Calmodulin-Dependent Protein Kinases|Intracellular Signaling Peptides and Proteins|ASB7 protein, human 27 ABI3BP 25585129 J Proteomics 2015 10.1016/j.jprot.2015.01.002 12 0 5 65 Animals|*Biomineralization|*Calcite|Tandem Mass Spectrometry|*Calcification, Physiologic|Eggshell|Avian Proteins|Proteomics|Egg Proteins|Eggs|Proteome|Chickens|Calcium-Binding Proteins|Embryonic Development 27 ABTB1 26201719 Genes Cells 2015 10.1111/gtc.12268 2 2 0 20 Humans|E2F1 Transcription Factor|*Fibroblasts|Retinoblastoma Protein|Apoptosis|Promoter Regions, Genetic|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|Genes, cdc|Genes, Tumor Suppressor|Cyclin-Dependent Kinase Inhibitor p16|Cell Line, Tumor|RBM38 protein, human|RNA-Binding Proteins|MOAP1 protein, human|Adaptor Proteins, Signal Transducing|Apoptosis Regulatory Proteins 31 ACAP2 26229970 J Immunol Res 2015 PMC4502309 10.1155/2015/429439 10 37 0 127 *Zymosan|*Phagocytosis|*Macrophages|ADP-Ribosylation Factors|rab GTP-Binding Proteins|Phagosomes|GTPase-Activating Proteins|Plasma Membrane 26 ACAP2 25853217 Cell Cycle 2015 PMC4614986 10.1080/15384101.2015.1026518 1 4 0 127 Animals|Humans|*Caenorhabditis elegans|*Apoptosis|Caspases|Caenorhabditis elegans Proteins|Signal Transduction|Downregulation|CNT-1 protein, C elegans|GTPase-Activating Proteins 26 ACAP2 25694427 J. Biol. Chem. 2015 PMC4423693 10.1074/jbc.M114.611301 8 3 3 127 Rats|Animals|*PC12 Cells|*Neurite Outgrowth|rab GTP-Binding Proteins|ADP-Ribosylation Factors|GTPase-Activating Proteins|Neurites|NGF protein, human|Nerve Growth Factor|Protein Transport|cnicin|*Sesquiterpenes|Protein Binding 26 ACOD1 25974697 Annu. Rev. Nutr. 2015 10.1146/annurev-nutr-071714-034243 33 0 3 3025 Animals|itaconic acid|*Succinates|*Anti-Infective Agents|*Anti-Bacterial Agents|Biotechnology|Carboxy-Lyases|Proteins|*Mammals 24 acrbp 26711247 Anim. Reprod. Sci. 2015 10.1016/j.anireprosci.2015.12.001 3 0 1 15 Swine|Male|Animals|Humans|Sperm Motility|*Triose-Phosphate Isomerase|*Glutathione Peroxidase|*Sperm|Seminal Plasma|Semen Analysis|Seminal Plasma Proteins|*Biomarkers|ACRBP protein, human|Carrier Proteins|FN1 protein, human|Fibronectin|Blotting, Western 39 acrbp 26597026 Anim. Reprod. Sci. 2015 10.1016/j.anireprosci.2015.11.010 2 0 0 15 Horses|Male|Animals|Mice|Guinea Pigs|*Testis|*Acrosin|Sexual Maturation|Spermatogenesis|Spermatozoa|ACRBP protein, human|*Carrier Proteins|Spermatogonia|Acrosome|Seminiferous Tubules|Spermatids|Spermatocytes|Western Blot|Reproduction|*Inferior Colliculi|Immunohistochemistry|Biomarkers|ACRBP protein, mouse 39 acrbp 26464818 Cell J 2015 PMC4601867 10.22074/cellj.2015.8 8 0 0 15 Humans|Male|*Up-Regulation|Carcinoma, Ductal, Breast|Cancer Biomarkers|Prognosis|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Antigens, Neoplasm|Seminal Plasma Proteins|RNA, Messenger|Membrane Proteins|Testis|*Breast Neoplasms|RHOXF2 protein, human|Homeodomain Proteins 39 acrbp 26339343 Int J Clin Exp Pathol 2015 PMC4555671 2 7 0 15 Male|*Carcinoma, Hepatocellular|*Down-Regulation|*Liver Neoplasms|*Testis|ACRBP protein, human|*Carrier Proteins|Cell Proliferation|RNA, Small Interfering|Apoptosis|Cell Cycle Proteins|RNA Interference|Gene Expression Regulation, Neoplastic|CCNE1 protein, human|Cyclin E|Hep G2 Cells|Cell Cycle|Cell Line, Tumor|RNA, Messenger 39 acrbp 26189257 Eur. J. Gynaecol. Oncol. 2015 2 0 0 15 Humans|Male|Female|*Testis|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|ACRBP protein, human|*Carrier Proteins|RNA, Messenger|*Proteomics 39 acrbp 26086592 Cancers (Basel) 2015 PMC4491699 10.3390/cancers7020824 2 5 0 15 Humans|Female|*Taxol|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Ovarian Cancer|Drug Resistance, Neoplasm|Antineoplastic Agents, Phytogenic|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Upregulation|Cell Proliferation|Viability, Cell|PSMA6 protein, human|Proteasome Endopeptidase Complex 39 acrbp 25994642 Asian J. Androl. 2015 PMC4492047 10.4103/1008-682X.152817 8 11 2 15 Male|Female|Zona Pellucida|Acrosome|Spermatozoa Capacitation|*Fertilization|Sperm-Ovum Interactions|proacrosin|Akrosin|Spermatozoa|Reactions, Acrosome|*Plasma Membrane|Membrane Glycoproteins|*Cell Communication|Immunoprecipitation|Sperm Head 39 acrbp 25867384 Genet. Mol. Res. 2015 10.4238/2015.March.27.23 3 0 0 15 Swine|Animals|Male|proacrosin|*Acrosin|*Phosphorylation|*Enzyme Precursors|*Sperm|Acrosome|Sperm Capacitation|Acrosome Reaction|Semen|Western Blot|Electrophoresis, Polyacrylamide Gel|Freezing|Binding Protein|Upregulation|Tyrosine 39 acrbp 25673160 Oncol. Rep. 2015 10.3892/or.2015.3792 5 0 0 15 *RNA Interference|*Oligonucleotide Array Sequence Analysis|*Computational Biology|*Liver Cancer|Carcinoma, Hepatocellular|CCND2 protein, human|*Cyclin D2|Gene Expression Regulation, Neoplastic|Cell Proliferation|Carrier Proteins|Apoptosis|Downregulation|Cell Line, Tumor|DNA-Binding Proteins|RNA, Messenger 39 ACRV1 26408346 Gastroenterology 2015 PMC4860725 10.1053/j.gastro.2015.09.013 13 15 0 6 Humans|Mice|Animals|*Proto-Oncogene Proteins p21(ras)|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|ACVR1B protein, human|*Activin Receptors, Type I|Cell Transformation, Neoplastic|Pancreas|Tumorigenesis|*Gastrointestinal Neoplasms|Cell Line, Tumor|Mutation|KRAS protein, human 57 ACRV1 26408346 Gastroenterology 2015 PMC4860725 10.1053/j.gastro.2015.09.013 13 15 0 6 Humans|Mice|Animals|*Proto-Oncogene Proteins p21(ras)|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|ACVR1B protein, human|*Activin Receptors, Type I|Cell Transformation, Neoplastic|Pancreas|Tumorigenesis|*Gastrointestinal Neoplasms|Cell Line, Tumor|Mutation|KRAS protein, human 57 ACTBP2 26284965 Arch Med Sadowej Kryminol 2015 10.5114/amsik.2015.53223 0 0 0 0 Humans|*Paternity|*Forensic Genetics|DNA Fingerprinting|Microsatellite Repeats|Genetics, Population|PCR|DNA|*Laboratory|Poland 67 ADAM7 26246218 Biol. Reprod. 2015 10.1095/biolreprod.115.130252 8 0 1 20 Humans|Male|Mice|Animals|*Epididymis|*Sperm|Sperm Motility|Testis|ADAM Proteins|Membrane Proteins|Fertility|Mice, Knockout|Cytoplasm|Adam7 protein, mouse 24 ADARB2 25951811 Genes Chromosomes Cancer 2015 10.1002/gcc.22251 5 0 0 83 34 ADARB2 25916332 J Headache Pain 2015 PMC4397221 10.1186/s10194-015-0511-y 0 1 0 83 34 ADARB2 25826567 RNA Biol 2015 PMC4615741 10.1080/15476286.2015.1017215 2 0 0 83 34 AFAP1L2 26446840 Mol. Biol. Cell 2015 PMC4666142 10.1091/mbc.E15-07-0483 3 57 1 160 *Cell Proliferation|src Tyrosine Kinases|SH3 Domain|Signal Transduction|Phosphorylation|TYRP1 protein, human|*Membrane Glycoproteins|Adaptor Proteins, Signal Transducing|Protein Binding|Adaptor Proteins, Vesicular Transport|Cell Cycle|Cell Line, Tumor|Protein Transport|Apoptosis|Cell Survival 30 AFAP1L2 26191231 Int J Clin Exp Pathol 2015 PMC4503102 3 2 0 160 Humans|*Carcinoma, Ductal, Breast|Prognosis|Kaplan-Meier Estimate|Biomarkers, Tumor|Immunohistochemistry|Disease-Free Survival|Cell Migration|Lymphatic Metastasis|Gene Expression Regulation, Neoplastic|Proportional Hazards Models|Cell Line, Tumor|Cell Proliferation|Up-Regulation|Cell Survival|*Breast Neoplasms 30 AFAP1L2 26045762 Int J Clin Exp Pathol 2015 PMC4440071 3 1 0 160 Humans|Retrospective Studies|*Osteosarcoma|Bone Neoplasms|Prognosis|Disease-Free Survival|Immunohistochemistry|Kaplan-Meier Estimate|Biomarkers, Tumor|Proportional Hazards Models|Up-Regulation|Adaptor Proteins, Signal Transducing|Disease Progression|RNA Interference|Multivariate Analysis 30 AFAP1L2 25980441 Oncotarget 2015 PMC4627235 10.18632/oncotarget.3777 7 17 4 160 Humans|4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone|Nitrosamines|*Epithelial Cells|Bronchi|*Microfilaments|Carcinogens|Lamellipodia|Cell Migration|Phosphorylation|Adaptor Proteins, Signal Transducing|Lung Cancer|*Translocation, Genetic|Cell Line|Cytoskeleton|Tobacco 30 AFAP1L2 25892537 Int. J. Cancer 2015 PMC4566921 10.1002/ijc.29570 6 6 0 160 Genome-Wide Association Study|*Epistasis, Genetic|*Melanoma|Skin Neoplasms|TERF1 protein, human|*Telomere-Binding Proteins|SNPs|Genetic Predisposition to Disease|Telomere|Gene Ontology 30 AGAP1 25785048 Int J Clin Exp Med 2015 PMC4358503 19 0 0 202 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|MicroRNAs|*Upregulation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Transcriptional Activation|Real-Time Polymerase Chain Reaction|MIRN1269 microRNA, human 25 AGAP1 25666757 Mol. Psychiatry 2015 10.1038/mp.2014.189 30 0 3 202 *Whole Exome Sequencing|*Genetic Heterogeneity|*Cerebral Palsy|Exome|Mutation|Genetic Predisposition to Disease|Sequence Analysis, DNA|Protein-Serine-Threonine Kinases 25 AMIGO2 26553931 J. Cell Biol. 2015 PMC4639856 10.1083/jcb.201503113 11 80 1 92 Mice|Animals|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|*Cell Survival|Endothelial Cells|Signal Transduction|3-Phosphoinositide-Dependent Protein Kinases|Phosphorylation|Plasma Membrane|Cell Proliferation|*Pathological Angiogenesis|Cells, Cultured|Apoptosis|Amigo2 protein, mouse|Membrane Proteins|Nerve Tissue Proteins 28 AMIGO2 26357653 Biomed Res Int 2015 PMC4556833 10.1155/2015/340218 15 14 2 92 Humans|Female|*Stromal Cells|Endometrium|Endometriosis|miRNAs|*Epithelial Cells|Cell Proliferation|Downregulation|Apoptosis|Cell Movement|Gene Expression Regulation|Upregulation|Signal Transduction|Cells, Cultured|Cell Adhesion|Gene Expression|MIRN183 microRNA, human 28 ANP32E 26455391 Mol. Cell 2015 PMC4620744 10.1016/j.molcel.2015.09.008 53 34 2 183 *Nucleosomes|Transcriptional Elongation Factors|High Mobility Group Proteins|Histones|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|DNA-Binding Proteins|Transcription Factors|Protein Binding|Binding Sites|Molecular Chaperones|SPT16 protein, S cerevisiae|FACT protein, S cerevisiae 36 ANP32E 26142279 EMBO Rep. 2015 PMC4552491 10.15252/embr.201540330 33 21 1 183 Humans|Animals|*Histones|INO80 protein, human|*DNA Helicases|*Homologous Recombination|Nucleosomes|Chromatin|Chromatin Assembly and Disassembly|DNA Breaks, Double-Stranded|Saccharomyces cerevisiae Proteins|Nuclear Proteins|Protein Binding 36 ANP32E 26034280 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4475971 10.1073/pnas.1504868112 29 6 1 183 *Nucleosomes|*Histones|*DNA Breaks, Double-Stranded|*DNA Repair|RBBP8 protein, human|Nuclear Proteins|Chromatin|Chromatin Assembly and Disassembly|Acetylation|Molecular Chaperones|Carrier Proteins|Phosphoproteins|DNA Damage|Histone Chaperones|DNA 36 anxa8 26700817 Oncotarget 2015 PMC4826250 10.18632/oncotarget.6639 4 2 1 85 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*Annexin A8|*Lymphatic Metastasis|KRT19 protein, human|Keratin-19|Sentinel Lymph Node Biopsy|Lymph Nodes|Neck Dissection|Neoplasm Staging|mRNA|Biomarkers, Tumor|Neoplasm Proteins 33 anxa8 26318045 Oncotarget 2015 PMC4695058 10.18632/oncotarget.4960 14 41 1 85 Humans|*Transcription Factor|Hedgehog Proteins|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Zinc Finger|*Pancreas|Zinc Finger Protein GLI1|Signal Transduction|Nuclear Proteins|Cellular Proliferation|Gene Expression Regulation, Neoplastic|Up-Regulation|Pancreatic Ducts|Adenocarcinoma|Cell Line, Tumor|Zinc|ZIC2 protein, human 33 anxa8 25918110 J Proteomics 2015 10.1016/j.jprot.2015.04.018 7 0 0 85 Humans|Female|*Proteomics|*Tandem Mass Spectrometry|Neoplasm Recurrence, Local|*MCF-7 Cells|Tumor Markers|Proteome|Neoplasm Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|*Complement Factor B 33 anxa8 25803307 PLoS ONE 2015 PMC4372349 10.1371/journal.pone.0119718 4 16 0 85 Female|Pregnancy|Mice|Animals|*Annexin A8|Sexual Maturation|*Epithelium|*Progenitor Cells|BRCA1 protein, human|BRCA1 Protein|Cell Proliferation|Mammary Glands, Animal|Cell Differentiation|Epithelial Cell|mRNA|Immunofluorescence|Gene Expression Profiling|Signal Transduction|Apoptosis|Cell Cycle|Gene Expression Regulation, Developmental|Proto-Oncogene Proteins c-kit 33 AOAH 26619808 Mol. Psychiatry 2015 PMC5414071 10.1038/mp.2015.177 22 17 2 51 Humans|*Apo E|Alzheimer disease type 1|*Alzheimer Disease|*Alleles|Presenilin-1|Apolipoprotein E4|Genotype|Heterozygote|Age of Onset|Pedigree|Genetic Predisposition to Disease|Mutation|Haplotype|TRIM22 protein, human|Tripartite Motif Proteins|Repressor Proteins|Minor Histocompatibility Antigens|PSEN1 protein, human 51 AOAH 26319989 Hum. Genet. 2015 PMC4570583 10.1007/s00439-015-1592-z 3 1 0 51 Humans|*Carotid Intima-Media Thickness|*Exons|Genetic Linkage|Polymorphism, Single Nucleotide|Allele Frequency|Genetic Predisposition to Disease|Genotype|Carotid Artery Diseases|Alleles|Phenotype|*Hispanic Americans|*African Continental Ancestry Group|Dominican Republic 51 AOAH 26138468 Am. J. Physiol. Gastrointest. Liver Physiol. 2015 10.1152/ajpgi.00163.2015 10 1 1 51 Pregnancy|Infant|Humans|Female|Swine|Infant, Newborn|Animals|Cattle|*Enterocolitis, Necrotizing|*Infant Formula|*Colostrum|*Gastrointestinal Microbiome|Preterm Infants|Animals, Newborn|Milk, Human|Intestinal Mucosa|Parenteral Nutrition, Total|Enteral Feeding|Intestines|Intestine, Small|Parenteral Nutrition|Food, Formulated|Permeability|Premature Birth|Diets 51 AOAH 25863487 Endocrine 2015 10.1007/s12020-015-0592-z 6 0 0 51 Humans|United States|*Thyroid Cancer, Papillary|DNA Copy Number Variations|Comparative Genomic Hybridization|Carcinoma, Papillary|Thyroid Neoplasms|Proto-Oncogene Proteins B-raf|Carcinoma|Thyroid Gland|Prognosis|Mutation|Number, Gene Copy|*Diploidy|Neoplasm Staging|Cohort Studies|ELMO1 protein, human|Adaptor Proteins, Signal Transducing 51 AOAH 25620174 J. Biol. Regul. Homeost. Agents 2015 1 0 0 51 Female|Humans|Dogs|Animals|*Pyometra|*Uteri|Endometrium|Dog Diseases|*Gene Expression|CXCL8 protein, human|Interleukin-8|PTGS2|*Microarray Analysis|Up-Regulation|Real-Time Polymerase Chain Reaction|SEMA7A protein, human|Antigens, CD|Semaphorins|GPI-Linked Proteins 51 APOBEC3D 26601257 Sci Adv 2015 PMC4643775 10.1126/sciadv.1500296 20 18 1 83 Animals|vif Protein|vif Gene Products, Human Immunodeficiency Virus|Cytosine Deaminase|HIV-1|Simian Immunodeficiency Virus|Cytidine Deaminase|Host-Pathogen Interactions|Lentiviruses|*Antiviral Agents|T-Lymphocytes 32 APOBEC3D 26544511 Oncotarget 2015 PMC4741873 10.18632/oncotarget.5483 10 25 1 83 Humans|vif Protein|vif Gene Products, Human Immunodeficiency Virus|HIV-1|APOBEC-3G Deaminase|Cytidine Deaminase|Cytosine Deaminase|Simian Immunodeficiency Virus|Virus Replication|CD4-Positive T-Lymphocytes|Protein Binding|Mutation|Mutagenesis|HEK293 Cells|*DNA|Genomics|vif protein, Human immunodeficiency virus 1|APOBEC3G protein, human|APOBEC3B protein, human 32 APOBEC3D 26459911 Sci Rep 2015 PMC4602211 10.1038/srep14969 6 4 1 83 Humans|APOBEC3A protein, human|Case-Control Studies|*Chinese|Proteins|Cytidine Deaminase|Genetic Predisposition to Disease|*Quantitative Trait Loci|*Lung Cancer|Polymorphism, Single Nucleotide|Allele|*Lung|Risk Factors|APOBEC3G protein, human|APOBEC-3G Deaminase|APOBEC3B protein, human|Minor Histocompatibility Antigens|APOBEC3H protein, human|Aminohydrolases 32 APOBEC3D 26394054 PLoS Pathog. 2015 PMC4578921 10.1371/journal.ppat.1005149 15 14 2 83 Humans|Animals|*Pan troglodytes|*Monkeys|*Lentiviruses|Simian Immunodeficiency Virus|Simian Acquired Immunodeficiency Syndrome|Hominidae|HIV-1|Evolution, Molecular|Phylogeny|*Antiviral Agents|Africa, West|APOBEC3G protein, human|APOBEC-3G Deaminase|APOBEC3 protein, human|Cytosine Deaminase 32 APOBEC3D 25889244 J Transl Med 2015 PMC4341880 10.1186/s12967-014-0370-3 23 0 0 83 Humans|*RNA Editing|*Cellular Reprogramming|Blast Crisis|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|*Cancer Stem Cell|Fusion Proteins, bcr-abl|Adenosine Deaminase|Disease Progression|ADAR1 protein, human|RNA-Binding Proteins 32 ARVCF 26645429 J. Pharmacol. Exp. Ther. 2015 10.1124/jpet.115.229880 6 6 0 78 Animals|*Phosphorylation|Serine Threonine Kinase|Signal Transduction|TNF Receptor-Associated Factor 2|*Neurons|Germinal Center Kinases|*Sequences, Consensus 79 ASTN1 26534937 Physiol. Genomics 2015 PMC4757026 10.1152/physiolgenomics.00097.2015 12 0 0 24 Rats|Animals|*Rats, Inbred Dahl|*Sodium Chloride|*Sodium Chloride, Dietary|*Hypertension|Rats, Inbred BN|Blood Pressure|Albuminuria|Kidney|Kidney Cortex|Chromosomes, Mammalian 40 ASTN1 25863124 Carcinogenesis 2015 PMC4462675 10.1093/carcin/bgv026 21 0 2 24 Humans|*Small Cell Lung Carcinoma|*RNA|*Exome|Lung Cancer|*Sequencing, Whole Exome|PTEN protein, human|PTEN Phosphohydrolase|Mutation|Retinoblastoma Protein|Tumor Suppressor Protein p53|Genes, Retinoblastoma|High-Throughput Nucleotide Sequencing|Alleles|Base Sequence|Genes, cdc|Sequencing, RNA|VPS13B protein, human|Vesicular Transport Proteins 40 ATRNL1 25957463 Exp. Cell Res. 2015 10.1016/j.yexcr.2015.04.020 9 12 1 17 Glycogen Synthase Kinase 3|*Osteoblasts|*Wnt Signaling Pathway|*Cell Differentiation|Wnt Proteins|beta Catenin|Bone Formation|Core Binding Factor Alpha 1 Subunit|T-Cell Factors|*Catenins|*Estrogens|Phosphorylations|Cell Nucleus|Proto-Oncogene Proteins c-akt|Cell Proliferation 30 ATRNL1 25922617 Mol Cytogenet 2015 PMC4411788 10.1186/s13039-015-0130-y 2 0 1 17 Child|Humans|*DNA Copy Number Variations|*Developmental Disabilities|Intellectual Disability|Chromosome Aberrations|Oligonucleotide Array Sequence Analysis|Chromosomes|Homozygote 30 ATRNL1 25892096 J. Bone Miner. Res. 2015 PMC4590282 10.1002/jbmr.2534 2 16 0 17 Mice|Animals|*Osteogenesis|AKAP13 protein, human|*A Kinase Anchor Proteins|*Minor Histocompatibility Antigens|*Proto-Oncogene Proteins|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteoblast|Guanine Nucleotide Exchange Factor|Cell Differentiation|RHOA protein, human|rhoA GTP-Binding Protein|Mesenchymal Stem Cells|Signal Transduction|Gene Expression Regulation|rho GTP-Binding Proteins|Bone|Receptors, Glucocorticoid 30 ATRNL1 25736627 Cell Prolif. 2015 PMC6496191 10.1111/cpr.12171 3 4 0 17 Mice|Animals|*Dental Pulp|*Cell Differentiation|Odontoblasts|*Receptors, Nerve Growth Factor|Stem Cells|Cell Proliferation|Cells, Cultured|Extracellular Matrix Proteins|Gene Knockdown Techniques|Alkaline Phosphatase|Nerve Growth Factors 30 ATRNL1 25727884 J. Cell. Biochem. 2015 10.1002/jcb.25148 1 2 0 17 Mice|Animals|RE1-silencing transcription factor|*Osteogenesis|*Cell Differentiation|Osteoblasts|*Repressor Proteins|Sp7 Transcription Factor|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Core Binding Factor Alpha 1 Subunit|Transcription Factors|BMP2 protein, human|3T3 Cells|shRNA|Cell Line|Skull|Transforming Growth Factor beta 30 ATRNL1 25601488 Lung Cancer 2015 10.1016/j.lungcan.2015.01.002 3 0 1 17 Humans|Male|Middle Aged|*Nonsmall Cell Lung Cancer|In Situ Hybridization, Fluorescence|Lung Neoplasms|ALK protein, human|Anaplastic Lymphoma Kinase|Crizotinib|Oncogene Proteins, Fusion|Receptor Protein-Tyrosine Kinases|Protein Kinase Inhibitors|Pyrazoles|Pyridines|Immunohistochemistry|Mutations|EML4-ALK fusion protein, human 30 BARHL1 26209643 Development 2015 PMC4550966 10.1242/dev.123091 22 1 1 73 Mice|Animals|*Organ of Corti|NEUROG1 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Hair Cells, Auditory|*Nerve Tissue Proteins|Stereocilia|Cell Differentiation|Cochlea|Gene Expression Regulation, Developmental|*Neurogenesis|Mice, Knockout|Cell Survival|Atoh1 protein, mouse|Neurog1 protein, mouse|Pou4f3 protein, mouse|Homeodomain Proteins|Transcription Factor Brn-3C|Barhl1 protein, mouse 35 BARHL1 25741244 Front Neuroanat 2015 PMC4330881 10.3389/fnana.2015.00012 2 1 0 73 *Hedgehog Proteins|*Mesencephalon|Body Patterning|Morphogenesis|Gene Expression Regulation, Developmental|In Situ Hybridization|Signal Transduction|Neurons 35 BARHL1 25698932 Front Cell Neurosci 2015 PMC4318345 10.3389/fncel.2015.00026 9 12 0 73 *Hair Cells, Auditory|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Organ of Corti|Nerve Tissue Proteins|Hair Cells, Auditory, Inner|Cochlea|Cell Differentiation|Ear, Inner|SOX2 protein, human|SOXB1 Transcription Factors|Gene Expression Regulation, Developmental|PAX2 Transcription Factor|GATA3 protein, human|GATA3 Transcription Factor|Organogenesis|Cell Cycle 35 BARHL2 26028559 Biochem. 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Commun. 2015 10.1016/j.bbrc.2015.05.044 4 2 0 57 Humans|*Genome-Wide Association Study|*Alzheimer Disease|SNPs|Genetic Predisposition to Disease|Genetic Association Studies|reelin protein|Cell Adhesion Molecules, Neuronal|Genotype|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing|Serine Endopeptidases|Extracellular Matrix Proteins|Signal Transduction|DAB1 protein, human 30 BARHL2 25619400 Genesis 2015 10.1002/dvg.22844 15 0 1 57 Mice|Animals|CASP3 protein, human|*Caspase 3|*Neural Plate|Hedgehog Proteins|*Apoptosis|Xenopus laevis|Homeodomain Proteins|Transcription Factors|Nervous System|Wnt Pathways 30 BHLHA15 26717480 PLoS ONE 2015 PMC4696804 10.1371/journal.pone.0145724 13 9 1 200 Humans|Mice|Animals|*Acute Pancreatitis|*Acute Disease|Acinar Cell|Exocrine Pancreas|Pancreatic Carcinoma|Pancreatic Cancer|Pancreas|Carcinoma, Pancreatic Ductal|*Gene Silencing|Mice, Knockout|Basic Helix-Loop-Helix Transcription Factors|Transcription Factor|Metaplasia|Cells, Cultured|Transcriptional Networks|Gene Expression Regulation|MIST1 protein, human|Mist1 protein, mouse 66 BHLHA15 26585400 Cancer Cell 2015 PMC4684751 10.1016/j.ccell.2015.10.003 84 39 3 200 *Stem Cell Niche|Endothelial Cells|Immunity, Innate|Lymphoid Cells|*Gastric Glands|*Stomach|Stomach Neoplasms|CDH1 protein, human|E Cadherin|Neoplastic Stem Cells|Cell Transformation, Neoplastic|WNT5A protein, human|Wnt-5a Protein|Cell Proliferation|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|Genes, ras 66 BHLHA15 26456005 Sci Rep 2015 PMC4601036 10.1038/srep14989 5 19 1 200 Mice|Animals|Transcription Factors|Hepatocytes|Cell Differentiation|Liver|*Fetus|*Transcription Factors, General|CCAAT Enhancer Binding Protein|Gene Expression Regulation, Developmental|Downregulation|Matrices, Extracellular|Cells, Cultured|Cytochrome P450|Oncostatin M|Epithelial Cells|Basic Helix-Loop-Helix Transcription Factors|Mist1 protein, mouse 66 BHLHA15 25975747 Mol Med Rep 2015 PMC4464163 10.3892/mmr.2015.3773 1 8 0 200 Mice|Animals|*Ceruletide|*Transcription Factors|Transcriptional Network|*Pancreatitis|Gene Expression Profiling|Databases, Genetic|Mice, Knockout|Gene Expression Regulation, Neoplastic|Computational Biology|Signal Transduction|Minichromosome Maintenance Complex Component 3|Gene Expression 66 BHLHA15 25928148 PLoS ONE 2015 PMC4416001 10.1371/journal.pone.0125153 6 25 0 200 *Acinar Cells|*Systems Biology|*Cell Differentiation|Transcription Factor|*Parotid Gland|Progenitor Cells|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation|Salivary Glands|RNA, Messenger 66 BLID 26629946 Oncol. Res. 2015 10.3727/096504015X14410238486568 0 3 0 49 Humans|*Genes, Suppressor|Genes, Tumor Suppressor|Apoptosis Regulatory Proteins|Apoptosis|Downregulation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Disease Progression|Antineoplastic Agents|BLID protein, human 187 BLID 25728273 FEBS Lett. 2015 10.1016/j.febslet.2015.02.013 9 1 2 49 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Cell Proliferation|Downregulation|3' UTR|Neoplasm Invasiveness|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|*Neoplastic Processes 187 BRAC1 26138306 Arch. Gynecol. Obstet. 2015 10.1007/s00404-015-3809-8 7 0 1 0 Humans|Female|*Endometriosis|Genital Neoplasms, Female|Genital Diseases, Female|Ovarian Neoplasms|Estrogens|*Rare Diseases 40 BRAC1 26098903 PLoS ONE 2015 PMC4476679 10.1371/journal.pone.0129808 0 7 2 0 Humans|*Head and Neck Cancer|*Promoter Regions, Genetic|DNA Methylation|CpG Islands|Head and Neck Squamous Cell Carcinoma|Carcinoma, Squamous Cell|Epigenetic|Human Papilloma Virus 40 BRAC1 25933381 PLoS Genet. 2015 PMC4416719 10.1371/journal.pgen.1005163 32 5 7 0 Female|Animals|*Drosophila melanogaster|Genome-Wide Association Study|*Pigmentation|Drosophila Proteins|Quantitative Trait Loci|DNA-Binding Proteins|Phenotypes|Polymorphism, Single Nucleotide|*Pigmentation Disorders|Base Sequence|*Abdomen 40 BRAC1 25599822 Reprod. Biomed. Online 2015 10.1016/j.rbmo.2014.11.010 9 0 0 0 Humans|Female|Rats|Mice|Animals|*DNA Breaks, Double-Stranded|*DNA Repair|*Ovarian Follicle|Rad51 Recombinase|Oocytes|Aging|Ovary|*DNA|Apoptosis|mRNA|ERCC2 protein, human|Xeroderma Pigmentosum Group D Protein 40 BRSK1 26444684 J. Neurochem. 2015 10.1111/jnc.13379 5 0 0 135 Mice|Animals|*Synaptic Vesicle|*Synapses|*Hippocampus|*Memory|*Fear|Terminals, Synaptic|Synaptic Plasticity|Neurotransmission|Long-Term Potentiation|Excitatory Postsynaptic Potentials|Mice, Knockout|Neurogenesis 48 BRWD3 26323392 BMC Med. Genet. 2015 PMC4593198 10.1186/s12881-015-0220-z 3 1 1 50 Male|Humans|*Cleft Palate|*Intellectual Disability|Cleft Lip|*Chromosome 1|Chromosome Deletion|Comparative Genomic Hybridization|Chromosomes, Human, X|Genes, X-Linked|*Hearing Impairment|Pedigree|*Disabled Persons|Growth Hormone 25 BRWD3 25877686 Hum. Genet. 2015 10.1007/s00439-015-1553-6 14 1 1 50 Humans|Female|Pregnancy|*Spasms, Infantile|DNA Copy Number Variations|Comparative Genomic Hybridization|Epilepsy|*Genomics|Mutations|Sequencing, Whole Exome|Genetic Predisposition to Disease|BRWD3 protein, human|Transcription Factors 25 BRWD3 25666827 EMBO Rep. 2015 PMC4388619 10.15252/embr.201439092 6 2 0 50 Animals|*Chromatin|*Histones|*Intellectual Disability|Histone Chaperones|Nucleosome|Transcription Factors|Nuclear Proteins|Cell Cycle Proteins|DNA-Binding Proteins|Drosophila Proteins|Drosophila melanogaster|Cell Nucleus|Binding Sites|Molecular Chaperones|*Gene Expression|Fertilization|Hira protein, Drosophila 25 BTG4 25951976 Biochem. Biophys. Res. 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Biochem. 2015 10.1080/09168451.2015.1008976 0 1 0 17 Male|Female|Mice|Humans|Animals|HEK293 Cells|Cell Cycle Proteins|cDNA|Amino Acid Sequence|Cloning, Molecular|mRNA|Cells, Epithelial|Btg4 protein, mouse 40 C1QTNF6 26648301 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2015 0 6 0 110 Humans|Female|*Complement C1q|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Neoplasm Invasiveness|Cell Movement|Cell Proliferation|Cell Line, Tumor|MicroRNAs|*Ovary|Vascular Endothelial Growth Factor A|Transfection|Tumor Necrosis Factors 33 C1QTNF6 26485223 Viral Immunol. 2015 10.1089/vim.2015.0067 5 0 0 110 Child|Humans|Infant|Child, Preschool|*Diabetes Mellitus, Type 1|*Enterovirus Infections|Enterovirus|HLA-DQ8 antigen|HLA-DQ Antigens|Genotype|HLA-DRB1 Chains|Single Nucleotide Polymorphisms|*Complement Factor B|Genetic Predisposition to Disease|Interferon-Induced Helicase, IFIH1|RNA, Viral|DEAD-box RNA Helicases|Feces|Immunity, Innate|Norway|C1qTNF6 protein, human|Collagen 33 C1QTNF6 26404464 Nat Commun 2015 PMC4598845 10.1038/ncomms9483 8 19 1 110 Humans|Mice|Animals|Rheumatoid Arthritis|Arthritis, Experimental|Synovial Membrane|Complement Activation|Complement Pathway, Alternative|Factor B|Disease Models, Animal|Mice, Transgenic|C1qTNF6 protein, human|Collagen|CTRP6 protein, mouse|Adipokines 33 C2CD4B 26428916 Pharm Biol 2015 10.3109/13880209.2015.1071414 6 0 0 16 3,4,5,4'-tetramethoxystilbene|*Endothelial Cells|*Stilbenes|Resveratrol|Apoptosis|Cell Line, Tumor|Effects, Antiangiogenesis|*Gene Expression Profiling|DMU-212|*Microarray Analysis|*Cell Death 24 C5orf42 26479702 Epigenetics 2015 PMC4867769 10.1080/15592294.2015.1099797 14 2 1 15 Humans|Adult|Child|Child, Preschool|*Twins, Monozygotic|DNA Methylation|CpG Islands|Processes, Epigenetic|Promoter Regions, Genetic|*Psychosis|Epigenetic|Schizophrenia|Genetic Predisposition to Disease|C5orf42 protein, human 24 C5orf42 25920555 Eur. J. Hum. Genet. 2015 PMC4717206 10.1038/ejhg.2015.84 20 1 1 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Genotype|Phenotype|Mutations|Polydactyly, Postaxial|Polydactyly|Membrane Proteins|Alleles|Sequencing, Next-Generation|*Cohort Studies|Heterogeneities, Genetic|Fingers|Toes 24 C5orf42 25877302 Hum. Mol. Genet. 2015 PMC4476446 10.1093/hmg/ddv137 14 0 2 15 Humans|Animals|Mice|Nephronophthisis, familial juvenile|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cilia|*Cerebellum|*Retina|*Ciliopathy|Cerebellar Diseases|Mutation|*Disease Models, Animal|Membrane Proteins|Cell Polarity|NPHP1 protein, human|Adaptor Proteins, Signal Transducing|C5orf42 protein, human|Jbts17 protein, mouse 24 C5orf42 25846457 Am. J. Med. Genet. A 2015 PMC4545386 10.1002/ajmg.a.37092 2 1 0 15 Humans|Orofaciodigital syndrome 6|*Orofaciodigital Syndromes|*Whole Exome Sequencing|*Exome|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|*Homozygote|Ciliopathy|Cerebellum|Polydactyly|Retina|Phenotype|Nervous System Malformations|Mutations|Membrane Proteins|Hamartoma 24 C5orf42 27081551 Hum Genome Var 2015 PMC4785546 10.1038/hgv.2015.45 3 0 1 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Exome|Orofaciodigital syndrome 6|Oral-Facial-Digital Syndrome|*Whole Exome Sequencing|*Face|Mutations|Phenotype|C5orf42 protein, human 24 CARD6 26238775 Oncol. Rep. 2015 10.3892/or.2015.4159 7 1 1 74 Humans|*Curcumin|*Cell Survival|*Lung Cancer|*Cell Cycle|*Cell Migration|*DNA Damage|Carcinoma, Non-Small-Cell Lung|Genes, cdc|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Line, Tumor|EIPR1 protein, human|Nuclear Proteins|Antineoplastic Agents|*Cell Division|*Gene Expression|Downregulation|CDC5L protein, human 30 CARD6 25815777 Mol Med Rep 2015 PMC4438957 10.3892/mmr.2015.3538 2 0 0 74 Humans|*Cantharidin|*DNA, Complementary|*Lung Cancer|*Cell Cycle|*Apoptosis|Carcinoma, Non-Small-Cell Lung|*DNA Damage|Cell Line, Tumor|Signal Transduction|Gene Expression Regulation, Neoplastic|Antineoplastic Agents|Curcumin|*Cell Division|Downregulation|*Microarray Analysis 30 CCDC170 26396922 Am J Cancer Res 2015 PMC4568782 11 0 0 50 Humans|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|Case-Control Studies|Genetic Predisposition to Disease|Alleles|Odds Ratios|Haplotype|Logistic Models|China 22 CCDC170 26036842 Breast Cancer Res. 2015 PMC4501298 10.1186/s13058-015-0591-2 10 4 2 50 Humans|Female|*Breast Density|Mammography|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Study, Genetic Association|Genotype|Phenotype|DNA Mutational Analysis|Risk Factors 22 CDC42EP4 26657011 Nat Commun 2015 PMC4682051 10.1038/ncomms10090 3 9 1 127 Mice|Animals|*Glutamate|*Septins|*Neuroglia|Purkinje Cells|Excitatory Amino Acid Transporter 1|Postsynaptic Current, Excitatory|Glutamate Transporter|Synapses|benzyloxyaspartate|Aspartic Acid|Cerebellum|Synaptic Transmission|Astrocytes|AMPA Receptors|Mice, Knockout|CDC42EP4 protein, mouse|Cytoskeletal Proteins|GTPase-Activating Proteins 20 CDC42EP4 25981171 Biol. Psychiatry 2015 PMC4600637 10.1016/j.biopsych.2015.03.030 37 12 5 127 *Schizophrenia|*Signal Transduction|Dorsolateral Prefrontal Cortex|Antipsychotic Agents|Cells, Pyramidal|Cell Division Cycle 42 Protein|Dendritic Spines|Serine Threonine Protein Kinases|RNA, Messenger 20 CDH16 26355662 Genet. Med. 2015 10.1038/gim.2015.127 24 0 0 53 Humans|*Retinal Dystrophies|*Alleles|Exome|Retinitis Pigmentosa|Pedigree|Genetic Association Studies|Phenotype|Mutation|Retina 48 CDH16 26273430 Cilia 2015 PMC4535764 10.1186/s13630-015-0019-8 4 4 1 53 Humans|Mice|Animals|Bardet-Biedl Syndrome 10|*Bardet-Biedl Syndrome|*Phenotype|Group II Chaperonins|Genotype|*Kidney|Cilia|Chaperonins|Mutation|Microtubule-Associated Proteins|Obesity 48 CDH19 26137091 Oncol Lett 2015 PMC4473523 10.3892/ol.2015.3107 20 0 3 36 *Cell Adhesion|*Tumors, Colorectal|Adenoma|Gene Expression Regulation, Neoplastic|mRNA|Gene Expression Profiling|Colonic Neoplasms|Upregulation|Adherens Junction 25 CDH19 25613075 Neonatology 2015 10.1159/000368878 2 0 1 36 Humans|Infant, Newborn|*Cleft Lip|*Comparative Genomic Hybridization|DNA Copy Number Variations|Poland|Cleft Palate|Abnormalities, Multiple|Phenotype|*Palate 25 CDH22 25952924 J Transl Med 2015 PMC4438459 10.1186/s12967-015-0506-0 6 4 2 30 Humans|*DNA Methylation|*Phenotype|*Asian Continental Ancestry Group|Medicine, Ayurvedic|Personalized Medicine 26 CDHR1 26668363 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4702997 10.1073/pnas.1509285113 26 0 0 33 Animals|*Cilia|Rhodopsin|Rod Cell Outer Segment|Peripherins|Photoreceptor Cells|Microscopy, Immunoelectron|Plasma Membrane|Eye Proteins|*Cadherins|TSPAN32 protein, human|Tetraspanins|Biological Transport|Xenopus laevis 34 CDHR1 26350383 Sci Rep 2015 PMC4642573 10.1038/srep13902 8 0 1 33 Humans|*Retinal Dystrophy|Homozygote|Genes, Recessive|DNA Mutational Analysis|Electroretinography|Retina|Mutations|Pedigree|Fluorescein Angiography|Stop Codons, Premature|Intron|Phenotype|Tomography, Optical Coherence|Visual Acuity|Nerve Tissue Proteins|CDHR1 protein, human|Cadherins 34 CDK2AP2 26362858 Int. J. Hematol. 2015 10.1007/s12185-015-1858-1 6 12 0 664 Humans|Adult|ribosomal protein S6 kinase, 70kD, polypeptide 2|*Ribosomal Protein S6 Kinases, 70-kDa|*Rapamycin|MTOR protein, human|*TOR Serine-Threonine Kinases|Proto-Oncogene Proteins c-akt|Signal Transduction|EIF4EBP1 protein, human|Phosphoproteins|Cell Cycle|Adaptor Proteins, Signal Transducing|*Acute Lymphoblastic Leukemia|Cell Proliferation|Cell Line, Tumor 32 CDK2AP2 26351750 Arch. Oral Biol. 2015 10.1016/j.archoralbio.2015.08.011 3 6 0 664 *Telomere|*Salivary Gland Neoplasms|Pleomorphic Adenoma|*DNA Methylation|*Promoter Regions, Genetic|Cyclin-Dependent Kinase Inhibitor p16|p14(ARF)|Parotid Neoplasms|Adenocarcinoma 32 CDK2AP2 26314435 Zhongguo Shi Yan Xue Ye Xue Za Zhi 2015 10.7534/j.issn.1009-2137.2015.04.019 1 0 0 664 *Lymphoma, Extranodal NK-T-Cell 32 CDK2AP2 25827071 Cancer Lett. 2015 10.1016/j.canlet.2015.03.036 8 8 2 664 Humans|Mice|Animals|*Tumor Suppressor Protein p53|*DNA Methylation|*Tretinoin|*Apoptosis|*Hepatocytes|Proto-Oncogene Proteins c-mdm2|*Promoter Regions, Genetic|HepG2 Cells|Caspases|CASP3 protein, human|Caspase 3|Down-Regulation|Upregulation 32 CDY1 26607720 Biol. Reprod. 2015 10.1095/biolreprod.115.135707 5 0 0 6 Humans|Male|Adult|Mice|Animals|Spermatogonia|*Stem Cell|*Adult Germline Stem Cells|Testes|Spermatogenesis|Stem Cell Transplantation|Cells, Cultured|Mice, Transgenic|Cryptorchidism|*Dyes|CDY1 protein, human|Nuclear Proteins 54 CDY1 26162009 J. Proteome Res. 2015 10.1021/acs.jproteome.5b00520 9 0 0 6 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Chromosomes, Human, Y|*Y-Chromosome Genes|*Transcriptome|Sperm Retrieval|*Sertoli Cell-Only Syndrome|Testis|Spermatogenesis|Spermatozoa|Infertility, Male|Sperm Count|*X Chromosome|Chromosome Deletion|*Protein Isoforms|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 54 CDY1 26149076 J. Assist. Reprod. Genet. 2015 PMC4595399 10.1007/s10815-015-0520-4 6 0 1 6 Humans|Male|*Oligospermia|*Azoospermia|Deleted in Azoospermia 1 Protein|Infertility, Male|*Gene Deletions|Chromosomes, Human, Y|Spermatogenesis|Gene Dosage|RNA-Binding Proteins|Case-Control Studies|Asian Continental Ancestry Group|Nuclear Proteins|CDY1 protein, human 54 CDY1 26000765 Sci Rep 2015 PMC4441132 10.1038/srep10551 4 0 0 6 Humans|Male|Deleted in Azoospermia 1 Protein|*Spermatogenesis|Y Chromosome, Human|Azoospermia|Infertility, Male|Haplotypes|Asian Continental Ancestry Group|*Allele|Limulus clotting factor C|*Arthropod Proteins|Gene Duplication|*Serine Endopeptidases|Case-Control Studies|Gene Deletion|RNA-Binding Proteins|*Homologous Recombination 54 CDY1 25901025 Mol. Hum. Reprod. 2015 PMC5009458 10.1093/molehr/gav022 3 0 1 6 Male|Humans|Cats|Animals|*Spermatogonia|Spermatogenesis|Testis|Azoospermia|ZBTB16 protein, human|Promyelocytic Leukemia Zinc Finger Protein|Limulus clotting factor C|*Arthropod Proteins|*Serine Endopeptidases|Proto-Oncogene Proteins c-kit|Oncogenes|Gene Deletion|MAGEA4 protein, human|Antigens, Neoplasm|Neoplasm Proteins 54 CDY1 25716801 Sci Rep 2015 PMC4341212 10.1038/srep08597 14 9 3 6 Humans|Mice|Animals|*Induced Pluripotent Stem Cells|POU5F1 protein, human|Octamer Transcription Factor-3|Embryoid Bodies|Cell Differentiation|Nanog Homeobox Protein|Germ Layers|SOXB1 Transcription Factors|Homeodomain Proteins|stage-specific embryonic antigen-4|Stage-Specific Embryonic Antigens|Kruppel-Like Transcription Factors|Fibroblasts|Cells, Cultured|SSEA-1|Genetic Vectors|Diabetes Mellitus 54 CECR2 26572217 J. Med. Chem. 2015 10.1021/acs.jmedchem.5b01514 37 0 3 63 *Lysine|SMARCA4 protein, human|Nuclear Proteins|Transcription Factors|Histones|Acetylation|*Protein Domains|DNA Helicases|Protein Processing, Post-Translational|Protein Binding|Models, Molecular 32 CECR2 26365797 Structure 2015 10.1016/j.str.2015.08.004 47 2 5 63 Humans|*Histones|*Protein Processing, Post-Translational|*Modifications, Histone|*Protein Domains|Transcription Factor TFIID|Nuclear Proteins|TATA-Binding Protein Associated Factors|Transcription Factors|Binding Sites|Histone Acetyltransferases|Acetylation|Lysine|Protein Binding|Models, Molecular|Cecr2 protein, human|BRD9 protein, human 32 CEND1 26321141 Stem Cell Reports 2015 PMC4618597 10.1016/j.stemcr.2015.07.012 6 16 1 30 Mice|Animals|*Astrocytes|Neurons|Neurogenesis|*Fibroblasts|Basic Helix-Loop-Helix Transcription Factors|Nerve Tissue Proteins|Neural Stem Cell|Cellular Reprogramming|POU Domain Factors|Transcription Factors|Cell Differentiation|*Embryonic Development|Cells, Cultured|Neurog2 protein, mouse|Cend1 protein, mouse|Membrane Proteins 26 cenpb 26246178 2015 10.1002/art.39316 13 0 1 198 Humans|Australia|*Sclerosis, Systemic|*Autoantibodies|Autoantigens|Raynaud Disease|Antibodies, Antinuclear|RNA Polymerase III|*Scleroderma, Localized|*Cohort Studies|Chromosomal Proteins, Non-Histone|DNA Topoisomerases, Type I 183 CES1P1 26076923 Pharmacogenomics J. 2015 PMC6329299 10.1038/tpj.2015.42 14 7 2 5 Humans|*Angiotensin-Converting Enzyme Inhibitors|Enalapril|Ramipril|Carboxylic Ester Hydrolases|Genotype|Liver|Prodrugs|Polymorphism, Single Nucleotide|moexipril|Tetrahydroisoquinolines|CES1 protein, human 20 CFDP1 26276885 Circ Cardiovasc Genet 2015 10.1161/CIRCGENETICS.115.001062 8 0 1 43 *Carotid Intima-Media Thickness|BCAR1 protein, human|*Crk-Associated Substrate Protein|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Atherosclerosis|Genome-Wide Association Study|Coronary Artery Disease|Risk Factors|Cohort Studies 40 CFDP1 26182435 Biosci. Rep. 2015 PMC4613681 10.1042/BSR20150111 5 3 1 43 Animals|*Phosphorylation|Escherichia coli|*Mammals|Phosphoproteins|Chromatin Assembly and Disassembly|Amino Acid Sequence|Protein Binding|Drosophila|Post-Translational Modifications|CREBBP protein, human|CREB-Binding Protein|Conserved Sequence|Epigenesis, Genetic|Yeti protein, Drosophila|Carrier Proteins|Drosophila Proteins 40 CFDP1 26153529 Anim. Genet. 2015 10.1111/age.12325 2 0 1 43 Animals|Dogs|*Transcriptome|*Pituitary-Adrenal System|Hypothalamo-Hypophyseal System|Corticosterone|Pituitary Gland|Corticotropin-Releasing Hormone|Receptors, Glucocorticoid|Adrenal Cortex|Stress, Physiological|NR4A1 protein, human|Nuclear Receptor Subfamily 4, Group A, Member 1 40 CHD6 25631877 Hum. Mol. Genet. 2015 PMC4406289 10.1093/hmg/ddv032 4 1 2 261 Humans|*Cystic Fibrosis Transmembrane Conductance Regulator|Epigenesis, Genetic|Chromatin|Enhancer Elements, Genetic|Transcription Factors|Chromatin Immunoprecipitation|Gene Expression Regulation|Binding Sites|Introns|Promoter Regions, Genetic|Cystic Fibrosis|Deoxyribonuclease I|Epithelial Cells|Caco-2 Cells|CHD6 protein, human|DNA Helicases|Nerve Tissue Proteins 31 CHI3L2 25826113 Transl Psychiatry 2015 PMC4429173 10.1038/tp.2015.9 9 7 0 30 Humans|Male|Mice|Animals|*RNA|RORA protein, human|*Retinoid-Related Orphan Receptor-alpha|*Antidepressive Agents|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genotype|*Biomarkers|Case-Control Studies|Microarray Analysis|Gene Expression Profiling|Retinoids|Lsp1 protein, mouse|Calcium-Binding Proteins 35 CHI3L2 25698171 Mult. Scler. 2015 10.1177/1352458514561906 0 0 1 30 *Multiple Sclerosis|*Chitinase|*Prognosis|Demyelinating Diseases|Lectins|Adipokines|Biomarkers|Disease Progression|Magnetic Resonance Imaging 35 CHRFAM7A 26567012 J. Neurovirol. 2015 PMC4866909 10.1007/s13365-015-0401-8 4 16 0 87 Humans|*HIV Infections|*Neurocognitive Disorder|Human Immunodeficiency Virus Type 1|*Brain|*Neurons|alpha7 Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptor|Cell Death|*Autopsy|Upregulation|Chrna7 protein, human 57 CILP2 26463451 Osteoarthr. Cartil. 2015 10.1016/j.joca.2015.09.020 7 0 0 28 Humans|*Proteomics|*Intervertebral Discs|Intervertebral Disc Degeneration|Nucleus Pulposus|Extracellular Matrix|*Fibrosis 34 CILP2 25951451 PLoS ONE 2015 PMC4423838 10.1371/journal.pone.0126363 5 4 1 28 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Japan|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genetic Loci|Case-Control Studies|Genotype|BCAR1 protein, human|Crk-Associated Substrate Protein 34 CILP2 25573592 Pathol. Oncol. Res. 2015 10.1007/s12253-014-9884-5 5 0 1 28 Humans|*Roma|Hungary|Allele Frequency|SNPs|Alleles|Genotype|Genetic Predisposition to Disease|Genetic Association Studies|Triglycerides|RFLP|N-Acetylgalactosaminyltransferases|MLXIPL protein, human|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|ANGPTL3 protein, human|Angiopoietin-like Proteins|GCKR protein, human|Adaptor Proteins, Signal Transducing|TRIB1 protein, human 34 CKAP2 26542785 Exp. Mol. Med. 2015 PMC4673469 10.1038/emm.2015.79 1 0 1 245 Humans|Male|Female|*Stomach Neoplasms|Prognosis|Immunohistochemistry|Proportional Hazard Model|Kaplan-Meier Estimate|Biomarkers, Tumor|Neoplasm Staging|Adenocarcinoma|Multivariate Analysis|Cisplatin|Cytoskeletal Proteins|Risk Factors|Cell Proliferation 50 CKAP2 26475974 Eur J Med Genet 2015 10.1016/j.ejmg.2015.10.006 2 0 0 245 Humans|Macrocephaly|Chromosome Deletion|Intellectual Disability|Comparative Genomic Hybridization|Phenotypes|In Situ Hybridization, Fluorescence|*Chromosome Structures 50 CKAP2 25809226 Mol. Carcinog. 2015 PMC6680233 10.1002/mc.22317 20 3 3 245 Humans|Female|*Down-Regulation|*Interleukin-6|*HeLa Cells|STAT3 protein, human|*STAT3 Transcription Factor|MIRN92 microRNA, human|*MicroRNAs|Cell Movement|Signal Transduction|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|3' Untranslated Regions|Cell Proliferation|Cell Line, Tumor|Uterine Cervical Neoplasms 50 CLEC11A 26564003 Sci Rep 2015 PMC4643236 10.1038/srep16658 8 3 1 80 Humans|Endothelial Cells|Carotid Endarterectomy|Carotid Stenosis|*Cell-Derived Microparticles|Plaque, Atherosclerotic|CXCL9 protein, human|*Chemokine CXCL9|Serum Markers|*Plaque, Amyloid|Inflammation|TNFRSF11B protein, human|Osteoprotegerin|Osteopontin 32 CLEC11A 26440592 Immunol. Res. 2015 PMC4689741 10.1007/s12026-015-8709-2 14 5 1 80 Humans|Intervertebral disc disease|*Intervertebral Disc Degeneration|Pilot Projects|*Herniated Disc|Spinal Stenosis|Low Back Pain|Lumbar Vertebrae|Injections, Epidural|*Biomarkers|Back Pain|Cytokines|Chemokines|Cohort Studies|Intervertebral Disc 32 CLIC6 26556046 PLoS ONE 2015 PMC4640871 10.1371/journal.pone.0142195 25 6 1 37 Mice|Animals|*Transcriptome|*Hippocampus|*Stress, Psychological|Disease Models, Animal|Choroid Plexus|Brain|Microarray Analysis|Kcne2 protein, mouse|Potassium Channels, Voltage-Gated 21 CLMN 26613086 J Immunol Res 2015 PMC4647058 10.1155/2015/101879 2 56 1 48 Humans|Genome-Wide Association Study|HLA-C|*Psoriasis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Haplotypes|Alleles|Case-Control Studies|TNFAIP3 protein, human|Tumor Necrosis Factor alpha-Induced Protein 3|Genes, MHC Class I|Intracellular Signaling Peptides and Proteins 29 CLMN 26485663 J. Steroid Biochem. Mol. Biol. 2015 10.1016/j.jsbmb.2015.10.012 5 4 0 48 *Vitamin D|*Vitamins|Calcitriol|25-Hydroxyvitamin D3 1-alpha-Hydroxylase|Vitamin D3 24-Hydroxylase|Receptors, Calcitriol|*Cholestanes 29 CLMN 25736056 J. Cell. Biochem. 2015 PMC6607438 10.1002/jcb.25129 14 4 0 48 Humans|*Calcitriol|dihydroxy-vitamin D3|*Vitamin D|Vitamins|CYP24A1|MCF7 Cells|Gene Expression Regulation, Neoplastic 29 CLSTN2 26415670 Neuropsychologia 2015 10.1016/j.neuropsychologia.2015.09.031 7 1 0 215 Humans|Aged|*Cross-Sectional Studies|WWC1 protein, human|*Intracellular Signaling Peptides and Proteins|*Phosphoproteins|*Cognition|Episodic Memory|*Hippocampus|Neuropsychological Tests|Polymorphism, Single Nucleotide|Aging|Genotype|Brain|Australia|CLSTN2 protein, human|Calcium-Binding Proteins|Membrane Proteins 32 CLSTN2 26171716 Neuropsychopharmacology 2015 PMC4707826 10.1038/npp.2015.206 11 2 0 215 Humans|Animals|Mice|CLSTN2 protein, human|*Calcium-Binding Proteins|calsyntenin-2, mouse|Parvalbumins|*Membrane Proteins|Interneurons|Synapses|Synaptic Transmission|Hippocampus|Neurons|Maze Learning|*Cognitive Dysfunction|Cerebral Cortex|gamma-Aminobutyric Acid|Mice, Knockout|*Cognition Disorders|Cognition 32 CLSTN2 26016521 J. Anim. Breed. Genet. 2015 10.1111/jbg.12167 6 0 0 215 Cattle|Male|Animals|*Genome-Wide Association Study|*Phenotype|*Genomics|Genotypes|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Red Meat|*Ultrasonography 32 CLSTN2 25889587 Stem Cell Res Ther 2015 PMC4431456 10.1186/s13287-015-0062-9 8 21 3 215 Animals|Humans|*Vascular Endothelial Growth Factor A|*Transcriptional Activation|*Adipose Tissue|*Cells, Stromal|Mesenchymal Stromal Cells|*Vascular Endothelial Growth Factors|Neovascularization, Physiologic|Intercellular Signaling Peptides and Proteins|Cell Differentiation|Cell Proliferation|Serrate-Jagged Proteins|Cell Movement|Cells, Cultured|Gene Expression Regulation|Signal Transduction|Calcium-Binding Proteins|Membrane Proteins 32 CMPK2 25861459 Lupus Sci Med 2015 PMC4379884 10.1136/lupus-2014-000080 31 3 4 29 Humans|*Lupus Erythematosus, Systemic|Lupus Nephritis|Interferon-alpha|*Antiviral Agents|Autoantibodies|Severity of Illness Index 21 CNN3 26175098 Appl. Biochem. Biotechnol. 2015 10.1007/s12010-015-1726-8 0 2 0 296 Humans|Animals|Cricetinae|*Glutamate|*Vibration|Proteomics|CHO Cells|Cricetulus|*Umbilical Cords|Mesenchymal Stem Cells|Mesenchymal Stem Cell Transplantation|Cell Differentiation|Neurons|Receptors, Ionotropic Glutamate 39 CNN3 26046660 PLoS ONE 2015 PMC4457629 10.1371/journal.pone.0128385 2 7 0 296 Animals|Mice|calponin|*Knockout Mouse|Microfilament Proteins|Calcium-Binding Proteins|Receptors, Antigen, B-Cell|Signal Transduction|B Cells|*Lymphocyte Activation|Phosphorylation|Syk Kinase|Protein-Tyrosine Kinases|Intracellular Signaling Peptides and Proteins|Precursor Cells, B-Lymphoid|Muscle, Smooth 39 COBLL1 26126603 J. Periodont. Res. 2015 10.1111/jre.12303 7 0 0 74 Mice|Animals|*Alveolar Bone Loss|*Multifactorial Inheritance|*Quantitative Trait Loci|*Periodontitis|*Inflammation|Porphyromonas gingivalis|*Biofilm|Dysbiosis|*Psychomotor Disorders|Host-Pathogen Interactions|Disease Models, Animal|*Perceptual Disorders 29 COBLL1 25925064 Asian-australas. J. Anim. Sci. 2015 PMC4412984 10.5713/ajas.14.0722 0 2 0 74 29 cornulin 26321370 Oral Oncol. 2015 10.1016/j.oraloncology.2015.08.008 4 0 0 53 Humans|*Proteomics|Chromatography, Liquid|Tandem Mass Spectrometry|Oral Cancer|Cancer Biomarkers|Carcinoma, Squamous Cell|Laser Capture Microdissection|Saliva|Proteins|Up-Regulation|Tissues, Epithelial|Peptides|Downregulation 27 cornulin 25846277 Clin Oral Investig 2015 10.1007/s00784-015-1467-7 5 0 1 53 *Carcinoma, Squamous Cell|*Mouth Neoplasms|*Down-Regulation|*Genomic Instability|Loss of Heterozygosity|Microsatellite Instability|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Microsatellite Repeats 27 COX6A2 26010876 PLoS ONE 2015 PMC4444189 10.1371/journal.pone.0127850 12 20 4 26 Swine|Animals|*MicroRNAs|*Cell Differentiation|Myogenesis|Myoblasts, Skeletal|Myotubes|Cell Proliferation|*Energy Metabolism|Muscle, Skeletal|Cell Line|*Genes, Mitochondrial|Adenosine Triphosphate 24 CPA6 26648591 Epilepsia 2015 10.1111/epi.13250 44 0 2 44 Infant|Child|Humans|*Exome|*Phenotype|Spasms, Infantile|Epilepsy|Mutation|Genetic Predisposition to Disease|Cohort Studies|KCNB1 protein, human|Shab Potassium Channels 24 CPA6 25875328 PLoS ONE 2015 PMC4395397 10.1371/journal.pone.0123180 3 2 1 44 Humans|Animals|Adolescent|*Epilepsy, Generalized|Carboxypeptidases A|Febrile Seizures|Juvenile Myoclonic Epilepsy|Mutations|Mutations, Missense|Substitutions, Amino Acid|Genotype|Epilepsy, Temporal Lobe 24 CPVL 26398045 Int. J. Oncol. 2015 10.3892/ijo.2015.3168 10 0 0 67 *Stomach Neoplasms|*Proteomics|olfactomedin|Prognosis|Biomarkers, Tumor|Granulocyte Colony-Stimulating Factor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 65 CRELD1 26036351 Pediatr Cardiol 2015 10.1007/s00246-015-1210-9 4 0 1 38 Humans|*DNA Copy Number Variations|*Tetralogy of Fallot|In Situ Hybridization, Fluorescence|Congenital Heart Defects|Multiplex Ligation-Dependent Probe Amplification|Exons|BMP4 protein, human|Bone Morphogenetic Protein 4 32 CROCC 25963817 J. Cell Biol. 2015 PMC4427792 10.1083/jcb.201412099 12 3 1 82 Humans|*Centrosome|*Interphase|*Mitosis|Centrioles|Spindle Apparatus|Tubulin|Microtubules|Cell Cycle Proteins|Cytoskeletal Proteins|NIMA-Related Kinases|Nerve Tissue Proteins|pericentrin|Antigens|Chromosome Segregation|Intracellular Signaling Peptides and Proteins|HeLa Cells|NEK2 protein, human|Nek5 protein, human 32 CRYGC 26310487 Int. J. Mol. Med. 2015 10.3892/ijmm.2015.2325 5 0 0 132 Humans|*Microphthalmos|Anterior segment mesenchymal dysgenesis|*Eye Abnormalities|*DNA Mutational Analysis|*Glaucoma|*Corneal Diseases|Mutations|Pedigree|Phenotype|*Tetrahymenina|Cornea|BEST1 protein, human|Bestrophins|CRYGD protein, human|gamma-Crystallins 65 CRYGC 26165230 J. Mol. Biol. 2015 10.1016/j.jmb.2015.07.001 4 1 1 132 gamma-Crystallins|Cataract, Autosomal Dominant Nuclear|*Cataract|*Mutation|Lens, Crystalline|Protein Conformation|Mutant Proteins|Molecular Chaperones|Amyloid Fibrils|Simulations, Molecular Dynamics 65 CRYGC 26045100 Twin Res Hum Genet 2015 10.1017/thg.2015.34 2 0 0 132 *Exome|*Whole Exome Sequencing|gamma-Crystallins|*Cataract|DNA Mutational Analysis|Pedigree|Genes, Dominant|Mutations|Connexins|Phenotypes|Amino Acid Sequence|Mutation, Missense|Sequence Analysis, DNA|Epigenesis, Genetic 65 CRYZ 26065919 Vaccine 2015 10.1016/j.vaccine.2015.05.024 17 0 0 488 Humans|Adult|*Rotavirus|*Rotavirus Vaccines|Rotavirus Infections|Antibodies, Neutralizing|Vaccines, Subunit|Antibodies, Viral|Vaccines, Synthetic|Immunoglobulin A|Viral Nonstructural Proteins|Immunoglobulin G|Adjuvants, Immunologic|Aluminum Hydroxide|RNA-Binding Proteins 164 CSMD2 25863124 Carcinogenesis 2015 PMC4462675 10.1093/carcin/bgv026 21 0 2 9 20 CST7 26247631 Oncotarget 2015 PMC4673165 10.18632/oncotarget.4208 11 21 0 128 Humans|*Cathepsin C|*Natural Killer Cells|Cytotoxicity, Immunologic|*Clonal Anergy|GZMB protein, human|Granzymes|Interferon-gamma|Interleukin-2|Cell Differentiation|Cytokines|Squamous Cell Carcinoma|Neoplastic Stem Cells|Monocytes|Cell Death|B Cells|Cystatins 39 CTAGE1 26332489 J. Oral Pathol. Med. 2015 10.1111/jop.12355 0 0 0 3 *Lichen Planus, Oral|SELE protein, human|*E-Selectin|Lichen Planus|Mouth Mucosa|T Cells|Skin 238 CTAGE1 26242300 J. Allergy Clin. Immunol. 2015 PMC4946641 10.1016/j.jaci.2015.05.049 21 11 1 3 Adult|Child|Humans|*Dermatitis, Atopic|6-sulfo sialyl Lewis X|*Th1 Cells|*Th2 Cell|*Oligosaccharides|*Eczema|*Lewis X Antigen|T-Lymphocyte Subsets|P-selectin ligand protein|*Membrane Glycoproteins|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Lymphocyte Activation|Antigens, Differentiation, T-Lymphocyte|Cytokines|Antigens, Neoplasm 238 CTAGE1 25748064 J. Allergy Clin. Immunol. 2015 10.1016/j.jaci.2015.01.020 29 0 2 3 Humans|*Dermatitis, Atopic|*Skin|T-Lymphocyte Subsets|CD8-Positive T-Lymphocytes|Lymphocyte Activation|Th2 Cells|CD4-Positive T-Lymphocytes|Antigens, Differentiation, T-Lymphocyte|Cytokines|Flow Cytometry|Immunoglobulin E|Antigens, Neoplasm 238 CUZD1 26503760 Mol. Psychiatry 2015 PMC4960452 10.1038/mp.2015.157 27 14 2 24 Rats|Animals|*Cocaine|*Astrocytes|*Lactate|*Conditioning, Classical|Memory|Cocaine-Related Disorders|*Neurons|Conditioning, Psychological|Amygdala|Cues|Basolateral Amygdala|Long-Term Memory|Self Administration|EGR1 protein, human|Early Growth Response Protein 1 35 CUZD1 26351932 Clin. Chem. Lab. Med. 2015 10.1515/cclm-2015-0376 9 2 0 24 *Crohn Disease|Colitis, Ulcerative|Indirect Immunofluorescence Assays|glycoprotein-2, pancreas|Autoantibodies|GPI-Linked Proteins|Immunoglobulin A|Pancreas|Immunoglobulin G|Enzyme-Linked Immunosorbent Assay|Membrane Proteins|Biomarkers 35 CUZD1 26273818 Inflamm. Bowel Dis. 2015 10.1097/MIB.0000000000000564 14 0 0 24 *Crohn Disease|*Autoantibodies|Colitis, Ulcerative|*Pancreas|GPI-Linked Proteins|Immunoglobulin A|*Phenotypes|Inflammatory Bowel Disease|Immunoglobulin G|Enzyme-Linked Immunosorbent Assay|Biomarkers|Membrane Proteins 35 CUZD1 25968583 J Crohns Colitis 2015 10.1093/ecco-jcc/jjv087 14 0 0 24 Adult|Humans|*Crohn Disease|*Prospective Studies|*Prognosis|Colitis, Ulcerative|Autoantibodies|*Cohort Studies|*Pancreas|Immunoglobulin A|GPI-Linked Proteins|Immunoglobulin G|Membrane Proteins|CUZD1 protein, human|GP2 protein, human 35 CUZD1 25702041 Mar. Biotechnol. 2015 10.1007/s10126-015-9624-1 6 0 1 24 Male|Animals|*Zebrafish|*Polymorphism, Single Nucleotide|*Protein, Dietary Plant|*Sequencing, RNA|Illumina Sequencing|Molecular Sequence Annotation|Genotype|Transcriptome|*Base Sequence|*Whole Exome Sequencing|Phenotype|Gene Expression Profiling|Genomics|Genome|Gene Library|Diet 35 CUZD1 25575461 Clin Res Hepatol Gastroenterol 2015 10.1016/j.clinre.2014.12.001 1 0 0 24 Humans|Animals|*Crohn Disease|*Paratuberculosis|Colitis, Ulcerative|Mycobacterium avium paratuberculosis|Autoantibodies|*Ruminants|*Pancreas|glycoprotein-2, pancreas|GPI-Linked Proteins|Immunoglobulin A|Fluorescent Antibody Technique, Indirect|Immunoglobulin G|Membrane Proteins|CUZD1 protein, human 35 CYP4X1 26227178 Genes Chromosomes Cancer 2015 10.1002/gcc.22279 0 0 2 8 *Transcriptome|Gene Fusion|*Databases, Genetic|Sequence Analysis, RNA|*Transcriptome Sequencing, Whole|Gene Expression Profiling|Cell Line, Tumor 26 CYP4X1 26095139 Xenobiotica 2015 10.3109/00498254.2015.1040102 3 0 0 8 Humans|*ATP-Binding Cassette Transporters|*Transcription Factors|*Reverse Transcriptase Polymerase Chain Reaction|*Alcoholics|*Smokers|arachidonate epoxygenase|*P-450 Enzymes, Cytochrome|cytochrome P-450 4X1|*Amygdala|*Cortex, Prefrontal|NR1I2 protein, human|Pregnane X Receptor|CYP1A1 protein, human|CYP1A1|CYP2E1|CYP1A2 protein, human|CYP1A2|Reductase, NADPH-P450 26 CYP4X1 25595103 BMC Res Notes 2015 PMC4322450 10.1186/s13104-015-0976-4 3 3 0 8 Humans|cytochrome P-450 4X1|*Cytochrome P-450 Enzyme System|Substrate Specificity|Amino Acid Sequence|Protein Binding|Binding Sites|Cytochrome P450 Family 2|Models, Molecular|Active Site 26 CYTL1 26117173 Gene 2015 10.1016/j.gene.2015.06.057 7 0 0 57 Pregnancy|Humans|Female|Animals|*Live Birth|*Transcriptome|*Blastocysts|*Implantations, Blastocyst|Embryo Transfer|Fertilization in Vitro|Embryonic Development|Embryo, Mammalian|Gene Expression Profiling|*Pregnancy, Multiple|Gene Expression Regulation, Developmental|Sequencing, Next-Generation|CYTL1 protein, human|Blood Proteins|Cytokines|EVI5 protein, human|Nuclear Proteins 34 CYTL1 25812627 J Immunotoxicol 2015 10.3109/1547691X.2015.1029147 12 0 2 57 Pregnancy|Humans|Female|Child, Preschool|Child|*Fluorocarbons|*Fetal Blood|*Prenatal Exposure Delayed Effects|Maternal Exposure|Environmental Pollutants|Cohort Studies|Common Cold|*Immune System Phenomena|*Gene Expression|Norway|CYTL1 protein, human|Blood Proteins|Cytokines 34 CYTL1 25749350 Cancer Genet 2015 10.1016/j.cancergen.2014.12.004 5 0 3 57 Humans|Finland|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|Exome|Genetic Predisposition to Disease|Colorectal Cancer|Polymorphism, Single Nucleotide|Pedigree|Germ-Line Mutation|Frequencies, Allele|CYTL1 protein, human|Blood Proteins|Cytokines 34 DACH2 26483211 Development 2015 PMC4712835 10.1242/dev.125674 8 6 0 37 Mice|Animals|HDAC9 protein, human|*Histone Deacetylases|*Repressor Proteins|*Signal Transduction|Myogenin|Muscle Denervation|Nuclear Proteins|Muscle, Skeletal|*Neurogenesis|Hdac9 protein, mouse|Dach2 protein, mouse 36 DACH2 25748626 PLoS Genet. 2015 PMC4352047 10.1371/journal.pgen.1005021 20 3 5 37 Humans|Mice|Animals|*Huntington Disease|*Myogenin|HTT protein, human|Huntingtin Protein|*Muscular Atrophy|Mice, Transgenic|Muscle, Skeletal|Disease Models, Animal|HDAC4 protein, human|*Histone Deacetylases|*Repressor Proteins|Muscle Contraction|Muscle Fibers, Skeletal|*Biomarkers|Energy Metabolism 36 DACH2 25744029 Biochem. Biophys. Res. Commun. 2015 10.1016/j.bbrc.2015.02.119 1 0 0 37 Humans|*Prospective Studies|*Urinary Bladder|*Carcinoma, Transitional Cell|*Urinary Bladder Neoplasms|*Prognosis|Cystectomy|Lymphatic Metastasis|Urothelium|Immunohistochemistry|Proportional Hazards Models|Kaplan-Meier Estimate|Biomarkers, Tumor|*Neoplastic Processes|Risk Factors|*Muscle 36 DACH2 25645944 Exp. Cell Res. 2015 10.1016/j.yexcr.2015.01.010 8 0 2 37 Male|Female|Mice|Animals|*Ovary|Sex Differentiation|Testis|Wnt4 Protein|Sex Determination Processes|Gonads|Mammalian Embryos|Forkhead Box Protein L2|Gene Expression Regulation, Developmental|Signal Transduction 36 DAZ1 26327816 Int. J. Biol. Sci. 2015 PMC4551758 10.7150/ijbs.11536 18 27 1 63 Male|Humans|Female|Animals|Spermatogenesis|Testes|Spermatocytes|Deleted in Azoospermia 1 Protein|RNA-Binding Proteins|Meiosis|Spermatogonia|mRNA|Y Chromosome|TYRP1 protein, human|*Membrane Glycoproteins|*Cell Differentiation|Amino Acid Sequence|Phylogeny 205 DAZ1 26232607 Gene 2015 10.1016/j.gene.2015.07.083 4 0 0 63 Humans|Male|Deleted in Azoospermia 1 Protein|*Infertility, Male|Oligozoospermia|Azoospermia|Chromosomes, Human, Y|Spermatogenesis|Asian|Genetic Predisposition to Disease|Gene Deletion|RNA-Binding Proteins|Fertility|Case-Control Studies|DAZ1 protein, human 205 DAZ1 26162009 J. Proteome Res. 2015 10.1021/acs.jproteome.5b00520 9 0 0 63 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Chromosomes, Human, Y|*Y-Chromosome Genes|*Transcriptome|Sperm Retrieval|*Sertoli Cell-Only Syndrome|Testis|Spermatogenesis|Spermatozoa|Infertility, Male|Sperm Count|*X Chromosome|Chromosome Deletion|*Protein Isoforms|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 205 DAZ1 26149076 J. Assist. Reprod. Genet. 2015 PMC4595399 10.1007/s10815-015-0520-4 6 0 1 63 Humans|Male|*Oligospermia|*Azoospermia|Deleted in Azoospermia 1 Protein|Infertility, Male|*Gene Deletions|Chromosomes, Human, Y|Spermatogenesis|Gene Dosage|RNA-Binding Proteins|Case-Control Studies|Asian Continental Ancestry Group|Nuclear Proteins|CDY1 protein, human 205 DAZ1 26000765 Sci Rep 2015 PMC4441132 10.1038/srep10551 4 0 0 63 Humans|Male|Deleted in Azoospermia 1 Protein|*Spermatogenesis|Y Chromosome, Human|Azoospermia|Infertility, Male|Haplotypes|Asian Continental Ancestry Group|*Allele|Limulus clotting factor C|*Arthropod Proteins|Gene Duplication|*Serine Endopeptidases|Case-Control Studies|Gene Deletion|RNA-Binding Proteins|*Homologous Recombination 205 DAZ1 25994570 Tumour Biol. 2015 10.1007/s13277-015-3546-4 8 0 2 63 Humans|Female|Male|AURKC protein, human|*Aurora Kinase C|*MCF-7 Cells|*Testis|Carcinoma, Ductal, Breast|*Transcriptome Analysis|*Oncogenes|Prognosis|Real-Time PCR, Quantitative|Biomarkers, Tumor|RNA, Messenger|Tumor Cells, Cultured|*Breast Neoplasms|DAZ1 protein, human|Deleted in Azoospermia 1 Protein 205 DAZ1 25973848 PLoS ONE 2015 PMC4431685 10.1371/journal.pone.0127007 9 1 0 63 Humans|Male|*Spermatozoa|*Fertility|*Transcriptome Analysis|Sperm Motility|Infertility, Male|Asthenozoospermia|mRNA|Transcriptome Profile|RNA 205 DAZ1 25901025 Mol. Hum. Reprod. 2015 PMC5009458 10.1093/molehr/gav022 3 0 1 63 Male|Humans|Cats|Animals|*Spermatogonia|Spermatogenesis|Testis|Azoospermia|ZBTB16 protein, human|Promyelocytic Leukemia Zinc Finger Protein|Limulus clotting factor C|*Arthropod Proteins|*Serine Endopeptidases|Proto-Oncogene Proteins c-kit|Oncogenes|Gene Deletion|MAGEA4 protein, human|Antigens, Neoplasm|Neoplasm Proteins 205 DAZ3 26232607 Gene 2015 10.1016/j.gene.2015.07.083 4 0 0 1 Humans|Male|Deleted in Azoospermia 1 Protein|*Infertility, Male|Oligozoospermia|Azoospermia|Chromosomes, Human, Y|Spermatogenesis|Asian|Genetic Predisposition to Disease|Gene Deletion|RNA-Binding Proteins|Fertility|Case-Control Studies|DAZ1 protein, human 20 DBR1 26715653 Ann. Rheum. Dis. 2015 10.1136/annrheumdis-2015-207802 3 0 1 69 Humans|*Alleles|*HLA-DRB1 Chains|*Rheumatoid Arthritis|Peptides, Cyclic|*Histocompatibility Testing|Autoantibodies|Genetic Predisposition to Disease|Genotype|Epitopes|Case-Control Studies 63 DDX10 26713367 Biochem. Biophys. Res. Commun. 2015 10.1016/j.bbrc.2015.12.069 0 1 0 68 Female|Humans|*Proto-Oncogene Proteins c-akt|*Ovarian Cancer|*Carcinoma, Ovarian Epithelial|*Cell Proliferation|*Downregulation|DDX10 protein, human|*DEAD-box RNA Helicases|Phosphatidylinositol 3-Kinases|NF-kappa B|Signal Transduction|Cell Movement|Cell Line, Tumor|Apoptosis|Tumor Xenograft Assay|Epigenesis, Genetic 29 DDX10 26004809 Leuk. Res. 2015 10.1016/j.leukres.2015.04.014 5 0 1 68 nuclear pore complex protein 98|*Translocation, Genetic|Nuclear Pore Complex Proteins|Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|*Leukemia, T-Cell|Nuclear Proteins|Karyotyping|In Situ Hybridization, Fluorescence|RAP1GDS1 protein, human|Guanine Nucleotide Exchange Factors|Immunophenotyping 29 DDX10 25701821 J. Gen. Virol. 2015 PMC4635492 10.1099/vir.0.000092 8 1 0 68 Humans|*HIV-1|*RNA, Small Interfering|Virus Replication|DDX10 protein, human|DEAD-box RNA Helicases|*DNA Helicases|HIV Infections|Host-Pathogen Interactions|Virion|Gene Knockdown Techniques|*Gene Library|*RNA, Double-Stranded 29 DDX25 26484580 Mol. Endocrinol. 2015 PMC4664233 10.1210/me.2015-1198 4 3 0 41 Male|Mice|Animals|*Testis|*Nuclear Receptor Subfamily 6, Group A, Member 1|Spermatogenesis|Spermatids|*Androgens|*Gonadotropin|Spermatocytes|Flutamide|DEAD-box RNA Helicases|mRNA|Gene Expression Regulation|Androgen Receptor Antagonists|mRNA Stability|Mice, Transgenic|Regions, 5' Flanking|Green Fluorescent Proteins|Ddx25 protein, mouse 39 DDX25 25910401 Horm Mol Biol Clin Investig 2015 10.1515/hmbci-2015-0004 2 2 0 41 Mice|Male|Animals|*Testis|*Chromatin|*Chromatin Assembly and Disassembly|*Spermatogenesis|Spermatid|*Gonadotropin|DEAD-box RNA Helicases|mRNA|Gene Expression Regulation|Mice, Knockout|Cell Nucleus|Ddx25 protein, mouse 39 DDX60 26643446 Rev. Med. Virol. 2015 10.1002/rmv.1865 11 2 1 64 Humans|*RNA, Viral|*Innate Immune Response|DEAD Box Protein 58|DEAD-box RNA Helicases|Type I Interferon|*Cytoplasm|Virus Replication|2-5A-dependent ribonuclease|Endoribonucleases|Signal Transduction|Antiviral Agents|HEK293 Cells 35 DDX60 26627478 BMC Mol. Biol. 2015 PMC4667504 10.1186/s12867-015-0049-1 3 8 2 64 Humans|Male|*Messenger RNA|Estrogen Nuclear Receptor|*Prostate|*Prostate Cancer|Cell Proliferation|Embryonic Stem Cells|Cell Line|Transfection|ESRRB protein, human 35 DDX60 26457795 Eur. J. Immunol. 2015 PMC4833184 10.1002/eji.201545794 11 32 3 64 Humans|Mice|Animals|DEAD Box Protein 58|DEAD-box RNA Helicases|Interferon-Induced Helicase, IFIH1|Interferon Type I|Virus Infection|Immunity, Innate|RNA, Viral|*DNA Helicases|Herpes Simplex Virus 1|Hepatitis C virus|Signal Transduction|DNA Viruses|DDX60 protein, human|DDX60 protein, mouse 35 DEXI 26616563 Nat Commun 2015 PMC4674669 10.1038/ncomms10069 56 1 5 27 Humans|Genome-Wide Association Study|SNPs|Genetic Predisposition to Disease|Quantitative Trait Loci|Autoimmune Diseases|Chromosome Mapping|Genome, Human|Regulatory Sequences, Nucleic Acid|*Relative Risk|Promoter Regions, Genetic|T-Lymphocytes 30 DEXI 26203907 PLoS ONE 2015 PMC4512731 10.1371/journal.pone.0132957 5 3 1 27 Humans|*Alleles|*Quantitative Trait Loci|Genome-Wide Association Study|*Multiple Sclerosis|*CD4-Positive T-Lymphocytes|Single Nucleotide Polymorphisms|*Suppressor of Cytokine Signaling Proteins|Genetic Predisposition to Disease|Linkage Disequilibrium|Lectins, C-Type|Monosaccharide Transport Proteins|Genotype|MHC class II transactivator protein|Nuclear Proteins|Trans-Activators|Suppressor of Cytokine Signaling 1 Protein|Case-Control Studies|SOCS1 protein, human 30 DEXI 26119467 Allergy 2015 PMC4583797 10.1111/all.12683 25 5 0 27 *Genome-Wide Association Study|*Quantitative Trait Loci|*Therapeutic Irrigation|*Asthma|Single Nucleotide Polymorphisms|*Bronchoalveolar Lavage Fluid|Genetic Predisposition to Disease|Genetic Association Studies|*Bronchial Lavage|*Epithelial Cells|Alleles|Genotype|Phenotype|Case-Control Studies 30 DGCR2 28955813 Biochem Biophys Rep 2015 PMC5600435 10.1016/j.bbrep.2015.11.015 1 0 0 182 Mice|Animals|Purkinje Cells|*Movement Disorders|Mice, Knockout|Rotarod Performance Test|Cerebellum|*Gait|Motor Activity 22 DGCR6 26561393 Hum. Genet. 2015 PMC4698300 10.1007/s00439-015-1606-x 8 5 1 67 Humans|Animals|Mice|*Cleft Lip|*Cleft Palate|*DNA Copy Number Variations|Genome-Wide Association Study|Genetic Predisposition to Disease|Phenotype|Polymorphism, Single Nucleotide|*Cohort Studies|Genomics|Genes, Regulator|Transcription Factors|Genes, Homeobox|SATB2 protein, human|Matrix Attachment Region Binding Proteins 24 DGCR6 26467088 BMC Genomics 2015 PMC4607176 10.1186/s12864-015-1958-6 5 0 1 67 Humans|Animals|*Introns|*Exon|*RNA Motifs|Base Sequence|Sequence Alignment|*DNA|Amino Acid Sequence|Chimpanzee|DiGeorge Syndrome|RNA 24 DGCR6 27081520 Hum Genome Var 2015 PMC4785558 10.1038/hgv.2015.4 6 1 1 67 Humans|In Situ Hybridization, Fluorescence|DiGeorge Syndrome|Conotruncal cardiac defects|*Heart Defects, Congenital|Comparative Genomic Hybridization|Abnormalities, Multiple|Shprintzen Golberg craniosynostosis|Arachnodactyly|Marfan Syndrome|Phenotype|Craniosynostoses|DGCR6 protein, human|Extracellular Matrix Proteins 24 DHRS2 25644336 J. Nutr. 2015 PMC4304022 10.3945/jn.114.202150 10 1 1 173 Female|Humans|*Lycopene|*Postmenopause|European Continental Ancestry Group|African Americans|Hispanic Americans|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genetic Loci|Body Mass Index|Logistic Models|Risk Factors 35 DHX33 26100019 Mol. Cell. Biol. 2015 PMC4525307 10.1128/MCB.00315-15 0 3 0 151 *Protein Biosynthesis|*Peptide Chain Initiation, Translational|Ribosomes|mRNA|DEAD-box RNA Helicases|Transcription, Genetic|Double-Stranded RNA|*Protein Processing, Post-Translational|Cell Proliferation|DNA Helicases 25 DHX33 25816776 Cell Host Microbe 2015 PMC4393362 10.1016/j.chom.2015.02.010 0 42 5 151 Mice|Animals|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|2-5A-dependent ribonuclease|*Endoribonucleases|Procaspase-1|*Virus Infection|Influenza A virus|Interleukin-1beta|Carrier Proteins|Double-Stranded RNA|Adaptor Proteins, Signal Transducing|Macrophages|RNA Interference|Nlrp3 protein, mouse 25 DLEU7 26662409 Genet. Mol. Res. 2015 10.4238/2015.December.8.6 5 0 0 16 Animals|*Polymorphism, Single Nucleotide|*Chickens|Linkage Disequilibrium|Haplotypes|Quantitative Trait, Heritable|Genome-Wide Association Study|*Phenotype|Body Weight|Reproduction|*Biological Phenomena 23 DLEU7 26475974 Eur J Med Genet 2015 10.1016/j.ejmg.2015.10.006 2 0 0 16 Humans|Macrocephaly|Chromosome Deletion|Intellectual Disability|Comparative Genomic Hybridization|Phenotypes|In Situ Hybridization, Fluorescence|*Chromosome Structures 23 DLEU7 26224146 Epigenetics 2015 PMC4622466 10.1080/15592294.2015.1076955 4 0 1 16 Humans|Fibrolamellar hepatocellular carcinoma|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Epigenome|DNA Methylation|Promoter Regions, Genetic|Long Interspersed Nucleotide Elements|Epigenesis, Genetic|SMARCA4 protein, human|Nuclear Proteins|Liver|Gene Expression Regulation, Neoplastic|Transcription Factors|DNA Helicases 23 DMXL2 26442671 Sci Rep 2015 PMC4595830 10.1038/srep14827 23 17 1 56 *Phosphorylation|Proteomics|Vacuolar Proton-Translocating ATPases|*Protein Transport|Endosomes|Protein Subunits|Signal Transduction|Cell Line|Epithelial Cells 27 DMXL2 26147891 J. Proteome Res. 2015 PMC4760104 10.1021/acs.jproteome.5b00498 6 5 0 56 Humans|*Chromosomes, Human, Pair 17|*Proteome|Receptors, Progesterone|Receptors, Estrogen|Receptor, ErbB-2|Triple-Negative Breast Cancer|Biomarkers, Tumor|*Isoforms 27 DMXL2 26093085 Oncotarget 2015 PMC4673176 10.18632/oncotarget.4164 9 20 2 56 Humans|*Epithelial-Mesenchymal Transition|Estrogen Receptor alpha|MCF-7 Cells|Antineoplastic Agents, Hormonal|Receptors, Estrogen|Signal Transduction|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|DMXL2 protein, human|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing 27 dnajc10 25575667 BMC Biol. 2015 PMC4316587 10.1186/s12915-014-0112-2 12 13 2 331 *Endoplasmic Reticulum|Protein Disulfide-Isomerases|HSP40 Heat-Shock Proteins|Redox|Molecular Chaperones|Calcium Signaling|TYRP1 protein, human|Oxidases|*Calcium Metabolism Disorders|*Calcium, Dietary|Disulfides|*Diffusion|Membrane Glycoproteins 32 DNAJC14 26055064 Prog Mol Biol Transl Sci 2015 10.1016/bs.pmbts.2015.02.012 2 0 0 65 *Protein Transport|Golgi Apparatus|Endoplasmic Reticulum|G-Protein-Coupled Receptors|*Molecular Chaperones|Plasma Membrane|Signal Transduction|Amino Acid Sequence|Endocytosis|*Cell Movement 20 DNAJC14 26018859 Zool. Res. 2015 PMC4790691 0 1 0 65 *HIV-1|*Dopamine|sodium-hydrogen exchanger regulatory factor|Sodium-Hydrogen Exchangers|Phosphoproteins|*Cell Line|CXCR4 protein, human|Receptors, CXCR4|RIPK1 protein, human|*Receptor-Interacting Protein Serine-Threonine Kinases|Signal Transduction|shRNA|*Erythrocyte Membrane|Protein Transport|*HIV Seropositivity|Virus Replication|Protein Binding|Cell Movement 20 DOC2B 26395669 Nat Commun 2015 PMC4598560 10.1038/ncomms9387 12 5 1 90 SNARE|Calcium-Binding Proteins|Protein Binding|Calcium|C2 Domains|Cell Membrane|Serine, Phosphatidyl|Nerve Tissue Proteins|Binding Sites|Phospholipids|*Membranes|Biological Transport 55 DOC2B 26200093 Endocrinology 2015 PMC5398638 10.1210/en.2015-1120 4 5 0 90 Animals|Mice|3T3-L1|*Biological Transport|Adipocytes|Insulin|Syntaxin 4|Phosphorylation|Glucose|Carrier Proteins|Protein Transport|2-Deoxyglucose|Proto-Oncogene Proteins c-akt|Signal Transduction|Plasma Membrane|Cell Differentiation|*Carbohydrate Metabolism 55 DOC2B 26195798 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4534243 10.1073/pnas.1502288112 10 1 1 90 SYT1 protein, human|Synaptotagmin I|*Synaptic Transmission|Synaptic Vesicles|Neurons|Calcium-Binding Proteins|SNARE Proteins|C2 Domain|Postsynaptic Current, Excitatory|Nerve Tissue Proteins|Neurotransmitter Agents|Plasma Membrane|Calcium|Hippocampus|Protein Binding|Binding Sites 55 DRAM2 26509668 PLoS ONE 2015 PMC4625034 10.1371/journal.pone.0140576 3 5 1 31 Humans|Genome-Wide Association Study|*Non-ST-Elevation Myocardial Infarction|Prospective Studies|Finland|Myocardial Infarction|Coronary Artery Disease|Genetic Predisposition to Disease|*Chromosome 3|Polymorphism, Single Nucleotide|Case-Control Studies|Odds Ratio|Genetic Variation|*Chromosome Structures|Cohort Studies|DRAM2 protein, human|Membrane Proteins 21 DRAM2 25983245 Am. J. Hum. Genet. 2015 PMC4457961 10.1016/j.ajhg.2015.04.006 11 0 0 31 Adult|Humans|*Retinal Dystrophy|Homozygote|Genes, Recessive|Exome|Mutations|Pedigree|Phenotypes|Whole Exome Sequencing|Membrane Proteins|Frameshift Mutation|*Autophagy|Case-Control Study|DRAM2 protein, human 21 DRAM2 25906080 Autophagy 2015 PMC4502665 10.1080/15548627.2015.1034409 35 0 0 31 Mice|Animals|*Bleomycin|*Autophagy|Autophagy-Related Proteins|Apoptosis|Cells, Epithelial|Idiopathic Pulmonary Fibrosis|Cysteine Endopeptidases 21 DRP2 26416664 J Transl Med 2015 PMC4587873 10.1186/s12967-015-0669-8 5 7 1 48 *Mesenchymal Stem Cells|*Telocytes|*Alveolar Epithelial Cells|*Lung|*Fibroblasts|*Lymphocytes|*Cells, Epithelial|Gene Expression Profiles|*Genes, X-Linked|Interstitial Cells of Cajal|Stem Cells|*Cell Count|Chromosomes 49 DRP2 26348328 PLoS ONE 2015 PMC4562647 10.1371/journal.pone.0137071 16 53 1 48 *Phytophthora infestans|*Dynamin 2|Plant Immunity|Potato|Tobacco|DNM2 protein, human|*Dynamins|Plant Proteins|Plant Diseases|Cell Death|PAMPs|E3 Ligase|*Endocytosis|Host-Pathogen Interactions 49 DRP2 26227883 Neuromuscul. Disord. 2015 PMC4920059 10.1016/j.nmd.2015.07.001 10 5 0 48 Humans|Male|Mice|Animals|Middle Aged|*Charcot-Marie-Tooth Disease|dystrophin-related protein 2|*Utrophin|periaxin|*Muscle Proteins|Myelin Sheath|Schwann Cells|Axons|Dystroglycan|Mutation|Neural Conduction|Phenotype|Knockout Mouse|Cell Membrane 49 EHBP1 26185455 Onco Targets Ther 2015 PMC4500625 10.2147/OTT.S84034 3 5 1 98 Humans|Male|Genome-Wide Association Study|*Polymorphism, Genetic|European Continental Ancestry Group|Genetic Predisposition to Disease|Asian Continental Ancestry Group|*Prostate Cancer|Alleles|Ethnicity|Odds Ratio|Risk Factors 29 EIF1AY 26162009 J. Proteome Res. 2015 10.1021/acs.jproteome.5b00520 9 0 0 31 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Chromosomes, Human, Y|*Y-Chromosome Genes|*Transcriptome|*Sertoli Cell-Only Syndrome|Sperm Retrieval|Testis|Spermatogenesis|Spermatozoa|Infertility, Male|Sperm Count|Sperm Injections, Intracytoplasmic|*X Chromosome|*Protein Isoforms|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 26 EIF1AY 26144214 J. Proteome Res. 2015 10.1021/acs.jproteome.5b00512 9 0 0 31 Humans|Male|*Genes, Y-Linked|Proteomics|Spermatogenesis|Azoospermia|Testis|Chromosomes, Human, Y|DEAD-box RNA Helicases|Transcription, Genetic|Proteins|Minor Histocompatibility Antigens|Cell Differentiation|DDX3Y protein, human 26 ELK4 26028036 Oncogene 2015 PMC4666830 10.1038/onc.2015.175 13 44 1 234 Mice|Animals|CDK2 protein, human|*Cyclin-Dependent Kinase 2|*Epidermal Growth Factor|*Signal Transduction Pathways|Cyclin-Dependent Kinases|*Cell Transformation, Neoplastic|Cell Cycle|Phosphorylation|Cyclin-Dependent Kinase Inhibitor p27|S Phase|Cell Lines|Cell Proliferation|Proto-Oncogene Proteins c-fos 110 ENOSF1 26499900 Cancer Chemother. Pharmacol. 2015 10.1007/s00280-015-2872-y 3 1 0 12 Humans|*Capecitabine|*Docetaxel|*Oxaliplatin|*Pharmacogenomic Testing|*Stomach Neoplasms|*Esophagogastric Junction|Esophageal Neoplasms|Fluorouracil|Organoplatinum Compounds|Taxoids|Deoxycytidine|Adenocarcinoma|Antineoplastic Combined Chemotherapy Protocols|Disease-Free Survival|Prognosis 23 ENOSF1 25800061 Expert Opin Drug Metab Toxicol 2015 10.1517/17425255.2015.1027684 9 0 0 12 *Pharmacogenetics|*Fluorouracil|Dihydrouracil Dehydrogenase (NADP)|Antimetabolites, Antineoplastic|Capecitabine|Thymidylate Synthase|Polymorphism, Genetic|Haplotypes|Genotype|Colorectal Neoplasms 23 ENOSF1 25752523 Pharmacogenomics J. 2015 10.1038/tpj.2015.9 1 0 0 12 Humans|6-methylthiopurine|*Mercaptopurine|*Whole Exome Sequencing|*Exome|Genome-Wide Association Study|Azathioprine|Colitis, Ulcerative|Crohn Disease|Phenotype|Immunosuppressive Agents|*Array-Based Comparative Genomic Hybridization|Methyltransferases|Genotype|Mutations|DNA Copy Number Variations|Genomics|RCC2 protein, human|Chromosomal Proteins, Non-Histone 23 ENOSF1 25691056 Oncotarget 2015 PMC4467446 10.18632/oncotarget.3289 5 0 1 12 Humans|*Capecitabine|*Colorectal Cancer|Antimetabolites, Antineoplastic|Fluorouracil|Methylenetetrahydrofolate reductase deficiency|Methylenetetrahydrofolate Reductase (NADPH2)|Deoxycytidine|Thymidylate Synthase|ABCB1 protein, human|*ATP Binding Cassette Transporter, Subfamily B|Polymorphism, Single Nucleotide|Cytidine Deaminase|Genotype|Haplotype|*Colonic Neoplasms|Homocystinuria|Muscle Spasticity|Psychotic Disorders 23 ENOSF1 25677901 Tumour Biol. 2015 10.1007/s13277-015-3163-2 10 0 0 12 Humans|*Proteomics|*Stomach Neoplasms|*Peptides|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Nonsmall Cell Lung Cancer|Biomarkers, Tumor|Clear Cell Renal Cell Carcinoma|*Protein Processing, Post-Translational|Lung Neoplasms|Kidney Neoplasms|SERPINA1 protein, human|alpha 1-Antitrypsin 23 EPB41L4B 26217016 Mol. Cell. Biol. 2015 PMC4561736 10.1128/MCB.00673-15 7 4 2 90 Humans|Dogs|Animals|HeLa Cells|*Signal Transduction|Actomyosin|RHOA protein, human|rhoA GTP-Binding Protein|Cytoskeleton|ROCK1 protein, human|rho-Associated Kinases|F-Actin|Rho Guanine Nucleotide Exchange Factors|Actin Cytoskeleton|Microfilament Proteins|Cell Shape|Madin Darby Canine Kidney Cells 23 EPC2 26297437 Neoplasia 2015 PMC4547437 10.1016/j.neo.2015.07.006 6 27 0 66 *Barrett Esophagus|beta Catenin|Wnt Signaling Pathway|Wnt3A Protein|Axin Protein|*Catenins|Metaplasia 54 EPC2 25988649 Am. J. Med. Genet. A 2015 10.1002/ajmg.a.36806 2 0 0 66 Child|Male|Humans|*Hirschsprung Disease|Chromosome 2, monosomy 2q|Chromosome Deletion|Comparative Genomic Hybridization|*Epilepsy|Abnormalities, Multiple|Developmental Disabilities|Phenotype|In Situ Hybridization, Fluorescence|Haploinsufficiency|*Musculoskeletal Abnormalities|*Chromosome Structures|Chromosomes, Human, Pair 2|*Red-Cell Aplasia, Pure 54 EPSTI1 26146465 Mediators Inflamm. 2015 PMC4469844 10.1155/2015/716315 8 18 0 50 *Hepatitis C|Antiviral Agents|Hepacivirus|Interferon-alpha|Virus Replication|*Cytokines|RNA, Viral|EPSTI1 protein, human|*Neoplasm Proteins|eIF-2 Kinase|Cell Line 37 EPSTI1 25898951 Am. J. Physiol. Endocrinol. Metab. 2015 10.1152/ajpendo.00023.2015 77 0 14 50 Humans|Mice|Animals|Diabetes Mellitus, Type 2|Adipose Tissue, Brown|Adipose Tissue, White|Adipocytes, Brown|*Biomarkers|Transcription Factors|Cell Differentiation|fibroblast growth factor 21|Fibroblast Growth Factors|Obesity|TCF21 protein, human|Basic Helix-Loop-Helix Transcription Factors|FBXO31 protein, human|Tumor Suppressor Proteins|F-Box Proteins|EBF3 protein, human|Ebf3 protein, mouse 37 EPSTI1 25772367 Cell Rep 2015 PMC4376630 10.1016/j.celrep.2015.02.040 31 4 6 50 Male|Animals|Rats|*CRISPR-Cas Systems|*Adult Germline Stem Cells|*CRISPR|Guide RNA|Gene Editing|Gene Targeting|*Mutagenesis, Site-Directed|Endonuclease, Cas9|Spermatogonia|Spermatogenesis|Sperm|Genome 37 EPSTI1 25590583 PLoS ONE 2015 PMC4295872 10.1371/journal.pone.0115352 5 27 0 50 Humans|EPSTI1 protein, human|*Neoplasm Proteins|*Genes, Neoplasm|Gene Expression Regulation, Neoplastic|Trans-Activators|Nuclear Proteins|Apoptosis|*Genes, cdc|Cell Line, Tumor|Signal Transduction|Cell Cycle Proteins|PSMC3IP protein, human 37 ERMN 25958037 Eur. J. Cancer 2015 PMC5916870 10.1016/j.ejca.2015.04.002 19 0 1 57 Adolescent|Child|Humans|*Cancer|*Survivorship|*Long-Term Care|Quality of Life|Survivors|Childhood Cancer Survivors|Delivery of Health Care|Registries|Treatment Outcome|Surveys|Europe 24 ERMN 25865550 Chem. Commun. (Camb.) 2015 10.1039/c5cc01305d 2 0 0 57 Magnetic Resonance Spectroscopy 24 ESX1 25935407 J. Hazard. Mater. 2015 10.1016/j.jhazmat.2015.04.065 11 1 1 100 Humans|Animals|Mice|Pregnancy|Female|*Maternal Exposure|phthalic acid|*Placenta|*Phthalic Acids|Placentation|Diethylhexyl Phthalate|Plasticizers|Implantations, Embryo|Pregnancy Outcomes|CASP3 protein, human|Caspase 3|Growth and Development 73 ETV7 26335051 Oncotarget 2015 PMC4745723 10.18632/oncotarget.5074 18 12 3 205 Humans|*Nasopharyngeal Carcinoma|*Downregulation|Nasopharyngeal Neoplasms|Cell Migration|Carcinoma|Epithelial-Mesenchymal Transition|SERPINE1 protein, human|*Plasminogen Activator Inhibitor 1|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Transcription Factors|*Neoplastic Processes|MicroRNAs|Signal Transduction 43 ETV7 26313525 Stem Cell Res 2015 PMC4600668 10.1016/j.scr.2015.08.003 0 20 3 205 Humans|*Hepacivirus|*Type I Interferon|*Hepatitis C|*Pluripotent Stem Cells|*Cell Differentiation|Hepatocyte|*Liver|Virus Replication|Immunity, Innate|Antiviral Agents|Host-Pathogen Interactions|Signal Transduction 43 FAIM3 26188803 Age (Dordr) 2015 PMC4506741 10.1007/s11357-015-9814-9 13 0 2 72 Humans|Male|Female|Aged, 80 and over|Aged|Leukocytes, Mononuclear|*Transcriptome|DNA Methylation|CpG Islands|*Aging|Epigenesis, Genetic|Epigenetic|*Sex Factors|*Inflammation|Interleukin 6|Genome-Wide Association Study|Biomarkers 23 FAIM3 26121490 Am. J. Respir. Crit. Care Med. 2015 10.1164/rccm.201502-0355OC 47 0 8 72 Humans|*Community-Acquired Infections|*Pneumonia|*Biomarkers|Calcitonin|Protein Precursors|*Intensive Care Unit|C-Reactive Protein|*Hospitalization|Sepsis|Calcitonin Gene-Related Peptide 23 FAIM3 25888699 J. Immunol. 2015 10.4049/jimmunol.1500222 5 0 1 72 Humans|Mice|Animals|Apoptosis Regulatory Proteins|B-Lymphocytes|fas Receptor|Lymphocyte Activation|Receptors, Fc|Membrane Proteins|Apoptosis|Immunoglobulin M|TOSO protein, mouse 23 FAIM3 25663104 Parasitol. Res. 2015 10.1007/s00436-015-4344-z 6 1 1 72 Male|Mice|Animals|*Eimeria|*Berberine|*Jejunum|Hydrogen Peroxide|Coccidiosis|*Gene Expression|Oocysts|NOS2 protein, human|Nitric Oxide Synthase Type II|Malondialdehyde|Glutathione|Messenger RNA|Feces 23 FAM167A 26379672 Front Immunol 2015 PMC4549647 10.3389/fimmu.2015.00437 3 3 1 62 Humans|*B Cells|Sjogren's Syndrome|*Regulatory Sequences, Nucleic Acid|Promoter Regions, Genetic|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Interferon Regulatory Factors|*Epigenetic|Case-Control Studies|Epigenesis, Genetic|FAM167A-BLK protein, human 25 FAM167A 25846585 Immunol. Res. 2015 PMC4438202 10.1007/s12026-015-8646-0 5 2 0 62 Humans|*Polymorphism, Single Nucleotide|*Dermatomyositis|*Chinese|Genetic Susceptibility|Polymyositis|Gene Frequency|Haplotypes|Genetic Association Studies|Allele|Genotype|Interstitial Lung Disease|Case-Control Studies|Idiopathic Inflammatory Myopathies|Autoimmune Diseases|FAM167A-BLK protein, human|BLK protein, human|src-Family Kinases 25 farp1 26471833 Vascul. Pharmacol. 2015 10.1016/j.vph.2015.10.003 14 2 0 105 Mice|Animals|*Rho Guanine Nucleotide Exchange Factors|*Vascular Endothelial Growth Factor A|*Endothelial Cells|Phylogeny|Cell Signaling|rho GTP-Binding Proteins|*Tumors|*Cell Count|*Endothelium|Rasgrf2 protein, mouse|ras Guanine Nucleotide Exchange Factors|FGD5 protein, mouse|Guanine Nucleotide Exchange Factors 26 farp1 26422651 ACS Chem. Biol. 2015 10.1021/acschembio.5b00679 5 1 0 105 *Kinase, Threonine|*Phosphorylation|*Mitogen-Activated Protein Kinases|Intracellular Signaling Peptides and Proteins|Signal Transduction|RhoGEF|Cytoskeleton|Microtubules 26 farp1 25668492 Neurosci. Lett. 2015 10.1016/j.neulet.2015.02.010 3 11 0 105 Rats|Animals|*Neurites|*Signal Transduction|*Cytoskeleton|RHOA protein, human|rhoA GTP-Binding Protein|Semaphorin|rho GTP-Binding Proteins|PC12 Cells|Neurons|Transfection 26 farp1 25586835 Stroke 2015 PMC4306534 10.1161/STROKEAHA.114.007649 13 12 2 105 *White Matter|Leukoencephalopathies|Brain|Genome-Wide Association Study|Alzheimer Disease|*Leukoaraiosis|Stroke|Magnetic Resonance Imaging|Hypertension|Risk Factors 26 FASTK 26693933 Hum. Genet. 2015 10.1007/s00439-015-1624-8 11 0 0 83 Humans|*Diabetic Retinopathy|*Exome|*Case-Control Study|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|*Phenotype|Genotype|Sequencing, Whole Exome|Cohort Studies|Diabetes Mellitus, Type 2 24 FASTK 26370583 RNA 2015 PMC4604428 10.1261/rna.052365.115 28 1 4 83 *RNA, Mitochondrial|*RNA Binding Protein|RNA|Mitochondria|Mitochondrial Proteins|Respiratory Complex I|Messenger RNA|Respiration, Cellular|*Gene Expression|Protein-Serine-Threonine Kinases 24 FASTK 26001296 Oncotarget 2015 PMC4599287 10.18632/oncotarget.4113 12 2 1 83 Child|Humans|Adult|*Transcriptome|Acute Lymphoblastic Leukemia|Fusion Proteins, bcr-abl|Prognosis|Translocation, Genetic|Gene Expression Profiling 24 FASTK 25704814 Cell Rep 2015 10.1016/j.celrep.2015.01.063 24 2 4 83 Humans|Mice|Animals|*RNA, Mitochondrial|*Mitochondria|Polyribonucleotide Nucleotidyltransferase|Electron Transport Complex I|Mitochondrial Proteins|Endoribonucleases|RNA Helicases|RNA|mRNA|Multienzyme Complexes|*Gene Expression|*Protein Isoforms|*Phosphorylation 24 FASTKD2 26370583 RNA 2015 PMC4604428 10.1261/rna.052365.115 28 1 4 49 *RNA, Mitochondrial|*RNA Binding Protein|RNA|Mitochondria|Mitochondrial Proteins|Respiratory Complex I|Messenger RNA|Respiration, Cellular|*Gene Expression|Protein-Serine-Threonine Kinases 22 FASTKD2 25683715 Cell Rep 2015 10.1016/j.celrep.2015.01.030 74 3 9 49 *RNA, Mitochondrial|RNA, Ribosomal, 16S|*RNA Processing, Posttranscriptional|Mitochondrial Ribosomes|Mitochondrial Proteins|RNA Precursors|Ribosomes|RNA-Binding Proteins|Mitochondria|Electron Transport Complex IV|Protein-Serine-Threonine Kinases 22 FBXO45 26506454 Semin. Cancer Biol. 2015 10.1016/j.semcancer.2015.10.003 27 0 0 190 *F-Box Proteins|*Epithelial-Mesenchymal Transition|Transcription Factors|Twist-Related Protein 1|Snail Family Transcription Factors|Homeodomain Proteins|FBXW7 protein, human|F-Box-WD Repeat-Containing Protein 7|Ubiquitin-Protein Ligases|Ubiquitination|Proteasome|Cell Line, Tumor 33 FBXO45 26487511 Mol. Pharmacol. 2015 PMC4702103 10.1124/mol.115.100925 5 6 0 190 Humans|Female|*Estrogens|Estrogens, Conjugated (USP)|estrophilin|*Receptors, Estrogen|Selective Estrogen Receptor Modulators|*Endometrium|Menopause|Estrogen Antagonists|bazedoxifene|Indoles|Endometriosis|Uterus 33 FBXO45 26068074 PLoS ONE 2015 PMC4466309 10.1371/journal.pone.0130288 3 39 0 190 Animals|Hairy, HRT1 protein|*bHLH Proteins|*Cell Nucleus|Repressor Proteins|F-Box Proteins|Ubiquitination|Transcription Factors|Cell Cycle Proteins|Nuclear Proteins|Ubiquitin-Protein Ligases|Receptors, Notch|Protein Binding|*Translocation, Genetic|Amino Acid Sequence|*Cytoplasm|Proteasome|SKP Cullin F-Box Protein Ligases 33 FCGRT 26252948 PLoS ONE 2015 PMC4529178 10.1371/journal.pone.0135141 2 10 1 1208 Humans|Fc receptor, neonatal|Endothelial Cells|*Response Elements|*Fc Receptor|*Histocompatibility Antigens Class I|Binding Site|Promoter Regions, Genetic|Transcription, Genetic|Gene Expression Regulation|Transfection|Base Sequence|Transcriptional Activation|Sp1 Transcription Factor|Mutagenesis, Site-Directed|Cell Lines|Genes, Reporter|Cell Nucleus|C EBPbeta 45 FCRL1 26604134 Hum. Mol. Genet. 2015 10.1093/hmg/ddv473 10 0 0 2 Humans|Leukocytes, Mononuclear|*B Cells|Antigens, CD19|Immunophenotyping|CD22 protein, human|Sialic Acid Binding Ig-like Lectin 2|Immunologic Memory|Flow Cytometry|*Phenotypes|B7-1 Antigen|Multiple Sclerosis, Relapsing-Remitting|Lymphocyte Count|*Imaging, Magnetic Resonance|FCRL1 protein, human|Membrane Proteins|FCRL2 protein, human|Receptors, Cell Surface 34 FCRL1 26410072 Mol. Genet. Metab. 2015 10.1016/j.ymgme.2015.09.005 4 0 1 2 Humans|*Parkinson Disease|*Down-Regulation|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|*Mutations|Glucosylceramidase|Genetic Predisposition to Disease|Protein-Serine-Threonine Kinases|Genotype|Jews|parkin protein|Ubiquitin-Protein Ligases|*Leukocytes|B-Lymphocytes|CD180 protein, human|Antigens, CD|FCRL1 protein, human|Membrane Proteins 34 FCRL1 25738996 Horm. Metab. Res. 2015 10.1055/s-0035-1545280 4 0 1 2 Humans|*Leukocytes, Mononuclear|*Hashimoto Thyroiditis|*Graves Disease|anti-thyroglobulin|Autoantibodies|FCRL4 protein, human|*Fc Receptor|Thyroid Gland|thyroid microsomal antibodies|FCRL2 protein, human|Receptors, Cell Surface|FCRL1 protein, human|Membrane Proteins|Gene Expression|*Leukocytes|Polymorphism, Genetic 34 FERD3L 26621503 Inflamm. Res. 2015 10.1007/s00011-015-0904-z 1 0 0 19 HDAC9 protein, human|*Histone Deacetylases|TWIST1 protein, human|*Twist-Related Protein 1|*Repressor Proteins|*Nuclear Proteins|*Gene Expression|Plaque, Atherosclerotic|Carotid Artery Diseases|Carotid Arteries|Stroke|*Plaque, Amyloid 21 FERD3L 25808521 Birth Defects Res. Part A Clin. Mol. Teratol. 2015 10.1002/bdra.23367 2 0 0 19 Humans|*Acrocephalosyndactylia|Comparative Genomic Hybridization|*Cranial Sutures|*Craniosynostosis|Twist-Related Protein 1|Chromosome Deletion|Nuclear Proteins|Phenotype|Mutation|Sutures 21 fes1 26278897 Environ Sci Pollut Res Int 2015 10.1007/s11356-015-5033-2 1 0 0 198 ferrous sulfide|Perchloroethylene|*Ferrous Compounds|Trichloroethylene|Dichloroethylenes|ethylene dichloride|Ethylene Dichlorides|Oxidation-Reduction|Halogenation|Iron|Groundwater|Kinetics|Biodegradation, Environmental|*Iron, Dietary 35 FGL1 26225745 Biochem. Biophys. Res. Commun. 2015 PMC4594872 10.1016/j.bbrc.2015.07.078 1 8 0 118 Mice|Animals|*Carcinoma, Hepatocellular|*Hepatocellular Cancers|MTOR protein, human|Mammalian Target of Rapamycin|Diethylnitrosamine|Proto-Oncogene Proteins c-akt|Carcinogenesis|Liver|Signal Transduction|Gene Expression Regulation, Neoplastic|Mechanistic Target of Rapamycin Complex 1|Cell Line, Tumor|Mice, Knockout|Fibrinogen 50 FILIP1L 26656364 Medicine (Baltimore) 2015 PMC5008509 10.1097/MD.0000000000002228 8 32 1 87 Humans|Mice|Animals|*Wnt Signaling Pathway|*NOD Mice|*SCID Mice|CTNNB1 protein, human|beta Catenin|MCF 7 Cells|MicroRNAs|Cancer Stem Cells|*Cell Cycle Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Self Renewal|Downregulation|MIRN204 microRNA, human 44 FILIP1L 26626643 Ann Hepatol 2015 10.5604/16652681.1184223 3 2 0 87 Animals|*Fasciola hepatica|*Trophoblasts|*Cell Surface Antigen|*Cholangiocarcinoma|Bile Ducts, Intrahepatic|Bile Duct Neoplasms|Fascioliasis|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|TACSTD2 protein, human|Antigens, Neoplasm|Transcription Factors 44 FILIP1L 26392303 Nat Commun 2015 PMC4595628 10.1038/ncomms9305 43 11 5 87 Humans|*Colorectal Cancers|Cetuximab|ErbB Receptors|Drug Resistance, Neoplasm|ras Proteins|Antineoplastic Agents|Antibodies, Monoclonal|Antibodies, Monoclonal, Humanized|Signal Transduction|Apoptosis|Cell Line, Tumor|EGFR protein, human 44 FILIP1L 26295306 Oncotarget 2015 PMC4694895 10.18632/oncotarget.4613 28 34 3 87 Humans|Adult|*Glioblastoma|*Proteomics|*Computational Biology|Brain Neoplasms|Neoplastic Stem Cells|Gene Expression Regulation, Neoplastic|Neural Stem Cells|Xenograft Model Antitumor Assays|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Biomarkers, Tumor|Up-Regulation|KIF15 protein, human|Kinesin|RHBDD1 protein, human|Serine Endopeptidases|DEPDC1 protein, human 44 FILIP1L 26022613 Gene 2015 10.1016/j.gene.2015.05.053 4 0 0 87 Humans|Mice|Animals|*5' Untranslated Regions|*Primates|*Tandem Repeats, Short|Transcription Start Site|Promoter Regions, Genetic|Mammals|Evolution, Molecular|Scandentia|Genes, Regulator 44 FILIP1L 26013103 Environ. Mol. Mutagen. 2015 PMC4755249 10.1002/em.21958 17 5 1 87 Humans|Male|*Welding|*Telomere Shortening|*DNA Methylation|Air Pollutants, Occupational|Occupational Exposure|Inhalation Exposure|Dust|Biomarkers|Oxidative Stress|Telomere|*Gases|Sweden 44 FILIP1L 25775029 PLoS ONE 2015 PMC4361622 10.1371/journal.pone.0119800 16 0 0 87 Female|Cattle|Animals|*Theca Cells|*Transcriptome|*Granulosa Cells|*Ovarian Follicle|Ovulation|CYP19A1 protein, human|Aromatase|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Ovary|*Biomarkers|Genes, Regulator|Steroid 17-alpha-Hydroxylase|Signal Transduction|Up-Regulation 44 FILIP1L 25649796 Stroke 2015 10.1161/STROKEAHA.114.007286 9 0 0 87 *Intracranial Aneurysm|Subarachnoid Hemorrhage|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Exome|Genotype|Pedigree|Phenotype|Risk Factors 44 FJX1 26536470 PLoS ONE 2015 PMC4633155 10.1371/journal.pone.0130464 0 5 1 72 Humans|*Nasopharyngeal Carcinoma|*Immunotherapy|HLA-A2|T-Lymphocytes, Cytotoxic|Antigens, Neoplasm|Cancer Vaccines|*Peptides|Lymphocyte Activation|Dendritic Cells|Nasopharyngeal Neoplasms|Amino Acid Sequence|*Immunologic Factors|Carcinoma|Cell Line, Tumor|Interferon-gamma|Cell Proliferation|Flow Cytometry|China 26 FJX1 25869446 Cell Adh Migr 2015 PMC4594470 10.1080/19336918.2014.1000069 24 0 4 72 Dendrites|Cadherins|Neurons|Synapses|Cell Adhesion Molecules|Signal Transduction 26 FKBP11 26417441 Immun Inflamm Dis 2015 PMC4578525 10.1002/iid3.65 6 15 0 61 Humans|Adult|Mice|Animals|Genome-Wide Association Study|*Lupus Erythematosus, Systemic|*B Cells|*Lupus Erythematosus, Discoid|*Immune Tolerance|Autoimmunity|Autoantibodies|*Hematopoiesis|Mice, Transgenic|*Lymphocyte Activation|Signal Transduction|Gene Expression|*Drug Tolerance 21 FKBP11 25915406 PLoS ONE 2015 PMC4411148 10.1371/journal.pone.0124744 17 34 1 61 Mice|Animals|*Sirtuin 3|Diabetes Mellitus, Type 2|*Palmitates|Insulin-Secreting Cells|Insulin Secretion|Endoplasmic Reticulum Stress|Islets of Langerhans|Insulin|Apoptosis|Glucose|*Pancreas|*Inducer Cell|MAP Kinase Signaling System|Free Fatty Acids|Gene Expression Regulation, Enzymologic|Viability, Cell|Sirt3 protein, mouse 21 FLVCR2 25906927 Ageing Res. Rev. 2015 10.1016/j.arr.2015.04.004 6 0 1 41 Humans|Aged|Aged, 80 and over|Sodium-Phosphate Cotransporter Proteins, Type III|*Brain Diseases|*Calcinosis|Neuroimaging|*Nervous System Malformations|Movement Disorders|Brain|*Molecular Biology|Mutation|Receptors, Virus 22 FLVCR2 25677735 Clin. Genet. 2015 10.1111/cge.12565 4 0 0 41 Humans|Male|Child|Infant|Encephaloclastic Proliferative Vasculopathy|*Hydranencephaly|*Mutations|Hydrocephaly|Brain|Phenotype|Syndrome|Membrane Transport Proteins|Receptors, Virus|Vascular Diseases|FLVCR2 protein, human 22 FMN1 26353782 BMC Cancer 2015 PMC4565013 10.1186/s12885-015-1635-9 10 18 1 3571 Humans|*Carcinoma, Non-Small-Cell Lung|*Cisplatin|*Lung Cancer|Drug Resistance, Neoplasm|Antineoplastic Agents|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|*Cell Lineage|DKK1 protein, human|Intercellular Signaling Peptides and Proteins 42 FMN1 25984239 Genome Med 2015 PMC4432772 10.1186/s13073-015-0149-z 20 4 3 3571 *Prognosis|*Heart Failure|Myocardial Infarction|Natriuretic Peptide, Brain|*Disease Progression|*Gene Expression Profiling|Electrocardiography|Peptide Fragments|Biomarkers|*Microarray Analysis 42 FMN1 25736034 Anim. Genet. 2015 PMC5024000 10.1111/age.12279 3 0 1 3571 Humans|Animals|*Goats|*Chromosomes, Human, Pair 10|Genome-Wide Association Study|*Comb and Wattles|GREM1 protein, human|*Intercellular Signaling Peptides and Proteins|Breeding|Allele|Chromosome Mapping|SNPs|Base Sequence|Phenotype|Genotype|Oligonucleotide Array Sequence Analysis 42 foxd4 26275051 PLoS ONE 2015 PMC4537205 10.1371/journal.pone.0135463 7 44 1 58 *Proteomics|Phosphatidylinositol 3-Kinases|*Myeloproliferative Disorders|JAK2 protein, human|Janus Kinase 2|Polycythemia Vera|Thrombocythemia, Essential|Primary Myelofibrosis|*Signal Transduction|Calgranulin A|Allele|Granulocytes|TOR Serine-Threonine Kinases 27 foxd4 25892704 Genesis 2015 10.1002/dvg.22854 5 0 0 58 Animals|*Ectoderm|*Blastula|Xenopus Proteins|Neural Plate|Xenopus laevis|Mesoderm|Gene Expression Regulation, Developmental|*Blastocyst|Cell Differentiation|Signal Transduction|Nervous System|Activation, Transcription|Forkhead Transcription Factors|siamois protein, Xenopus 27 FOXI3 26550799 Dev. Biol. 2015 PMC4688051 10.1016/j.ydbio.2015.09.022 13 8 0 37 Mice|Animals|Ectoderm|Neural Plate|Zebrafish Proteins|Gene Expression Regulation, Developmental|Zebrafish|Fibroblast Growth Factors|Ear, Inner|Forkhead Transcription Factors|Hindbrain|Foxi3 protein, mouse 30 FOXI3 26450968 Development 2015 PMC6517835 10.1242/dev.124172 7 3 0 37 Mice|Animals|*Tooth Crown|Odontogenesis|Epithelium|Morphogenesis|Ameloblasts|Cell Differentiation|BMP4 protein, human|Bone Morphogenetic Protein 4|Tooth|Epithelial Cell|Transcription Factor|Mesoderm|Signal Transduction|Molar|Fibroblast Growth Factors|Gene Expression Regulation, Developmental|Crowns|Foxi3 protein, mouse 30 FOXI3 25963515 Dev. Dyn. 2015 10.1002/dvdy.24290 0 0 0 37 Animals|*Oryzias|*Embryonic Development|Zebrafish|*Cell Differentiation|Gills|Epidermal Cells|Epidermis|In Situ Hybridization|Water-Electrolyte Balance|Sodium-Potassium-Exchanging ATPase|Ion Transport|Salinity 30 FOXI3 25655429 Am. J. Med. Genet. A 2015 PMC4591042 10.1002/ajmg.a.36895 10 0 0 37 Humans|Infant|Female|Mice|Dogs|Animals|Comparative Genomic Hybridization|*Carotid Artery, Internal|In Situ Hybridization, Fluorescence|Aural Atresia, Congenital|Chromosome Deletion|Abnormalities, Multiple|Ear Canal|Ectoderm|Ear, Inner|Microtia|Phenotypes|Forkhead Transcription Factors|Vascular Malformations|Endoderm|Foxi3 protein, human|Foxi3 protein, mouse 30 FOXJ3 26578569 Nucleic Acids Res. 2015 PMC4770209 10.1093/nar/gkv1120 0 11 1 127 *Forkhead Transcription Factors|Chromatin|Gene Expression Regulation|Chromatin Immunoprecipitation|Binding Sites|Forkhead Box Protein O3|Protein Binding|Promoter Regions, Genetic|DNA Sequence|Cell Line, Tumor|Gene Expression|DNA 21 FOXN2 25977169 Cancer Genomics Proteomics 2015 14 1 0 138 Humans|Adult|*Glioblastoma|*Forkhead Box Transcription Factors|*Transcriptome|*Transcriptome Profiling|Brain Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|RNA, Messenger 28 FOXN4 26361845 Gene 2015 10.1016/j.gene.2015.09.011 0 0 0 65 Animals|Rabbits|*Vascular Remodeling|*Transcription Factors|*Smooth Muscle Cells|Muscle, Smooth, Vascular|Cultured Cells|Gene Expression Regulation|Oligonucleotide Array Sequence Analysis|Arteries|Extracellular Matrix|Up-Regulation|Gene Expression Profiling|Apoptosis|Phenotype|Downregulation|Gene Clusters 54 FOXN4 26177550 PLoS ONE 2015 PMC4503745 10.1371/journal.pone.0132013 4 0 1 65 Mice|Animals|*Neurites|VLDL receptor|*Receptors, LDL|Retinal Neovascularization|Retina|Retinal Vessels|*Neovascularization, Pathologic|Mice, Knockout|Diabetic Retinopathy|Vascular Endothelial Growth Factor A|Disease Models, Animal|Endothelium, Vascular 54 FOXN4 26062426 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2015 2 4 0 65 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Signal Transduction|Carcinoma, Squamous Cell|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|RNA Interference|Cell Line, Tumor|Apoptosis|NOTCH1 protein, human|Receptor, Notch1|DLL4 protein, human|Intercellular Signaling Peptides and Proteins 54 FOXN4 25966682 Mol Brain 2015 PMC4429372 10.1186/s13041-015-0118-x 16 19 1 65 Mice|Animals|Amacrine Cells|*Neurogenesis|Retina|Retinal Horizontal Cells|Cell Differentiation|Retinal Ganglion Cells|Gene Expression Regulation, Developmental|TFAP2B protein, human|*Transcription Factor AP-2|Cells, Glial|Forkhead Transcription Factors 54 FOXN4 25794677 Dev. Biol. 2015 10.1016/j.ydbio.2015.02.023 10 0 1 65 ONECUT2 protein, human|*Homeodomain Proteins|*Retina|Paired Box Transcription Factors|Transcription Factor PAX6|Eye Proteins|Repressor Proteins|Cell Differentiation|Retinal Horizontal Cells|Retinal Ganglion Cells|Gene Expression Regulation, Developmental|Progenitor Cell|Photoreceptors, Cone 54 FRMD4A 25864118 Chin J Integr Med 2015 10.1007/s11655-015-2053-1 4 0 1 33 Humans|*RNA, Micro|*Endothelial Cells|*Hypertension|RNA, Messenger 26 FRMD4A 25862628 Int J Epidemiol 2015 PMC4588868 10.1093/ije/dyv048 66 2 8 33 Pregnancy|Humans|Female|*Birth Weight|*DNA Methylation|*B-DNA|CpG Islands|Maternal Exposure|Epigenesis, Genetic|Prenatal Exposure Delayed Effects|Blood, Cord|Smoking|Genome-Wide Association Study|Tobacco Smoking|*Protein Processing, Post-Translational 26 FXYD5 26494976 Cancer Inform 2015 PMC4603440 10.4137/CIN.S30565 5 4 1 129 Humans|Female|*Ovarian Cancer|Prognosis|*Neoplastic Processes|Survival Analysis|Cell Line, Tumor|Carcinoma, Ovarian Epithelial|*Biomarkers|Ovary|Cell Adhesion|FXYD5 protein, human|Membrane Glycoproteins|Neoplasm Proteins 81 FXYD5 26458963 Mol Med Rep 2015 PMC4626168 10.3892/mmr.2015.4363 5 6 1 129 Humans|Animals|Mice|Carcinoma, Hepatocellular|Liver Neoplasms|*SCID Mice|*Cancer Stem Cells|*Tumorigenesis|Cell Line, Tumor|Antineoplastic Agents|Neoplasm Proteins|Apoptosis|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|*Liver|Neoplasm Transplantation|Prognosis|*Drug Targeting|RNA Interference|*B Cell Lymphoma|*DNA 81 FXYD5 26410457 Respir Physiol Neurobiol 2015 10.1016/j.resp.2015.09.008 6 6 0 129 Humans|*Alveolar Epithelial Cells|Sodium-Potassium-Exchanging ATPase|*Ion Transport|Phosphoproteins|Membrane Proteins|Sodium|Acute Respiratory Distress Syndrome|*Biochemical Phenomena|Fluid Balance 81 GABRG1 26577018 Neuropharmacology 2015 10.1016/j.neuropharm.2015.11.003 27 0 4 26 Mice|Animals|*Autistic Disorder|*Butyric Acid|*Social Behaviors|Grooming|Mice, Inbred Strains|Autism Spectrum Disorders|Behavior, Animal|Disease Models, Animal|*Frontal Cortex|Cortex, Prefrontal|Cognition 48 GABRG1 26250693 Alcohol. Clin. Exp. Res. 2015 PMC4558268 10.1111/acer.12807 15 0 2 26 Humans|*Alcoholism|*Alleles|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Linkage Disequilibrium|Genotype|Receptors, GABA-A|DNA Mutational Analysis|*Chromosome Structures|GABRA2 protein, human 48 GABRG1 26087834 Alcohol. Clin. Exp. Res. 2015 PMC4490958 10.1111/acer.12749 9 1 0 26 *Ethanol|*Alcohol Drinking|Alcohol Abuse|*Genotype|Alcoholic Intoxication|GABA A Receptor|Polymorphism, Single Nucleotide|Dose-Response Relationship, Drug|*Acclimatization 48 GABRG1 25655461 Gene 2015 PMC6675570 10.1016/j.gene.2015.01.064 4 0 0 26 *Alcoholism|*Genetic Markers|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Brain|Epistasis, Genetic|*Chromosome 48 GABRG1 25636713 Neurology 2015 PMC4366091 10.1212/WNL.0000000000001326 29 5 5 26 Humans|*Receptors, GABA-A|Neurons|Seizures|Hippocampus|Brain|Autoantibodies|HEK293 Cells 48 GABRP 26634217 J Immunol Res 2015 PMC4655060 10.1155/2015/602154 2 0 1 19 Humans|Female|*Lupus Erythematosus, Systemic|SNPs|Genotype|Gene Frequency|Genetic Predisposition to Disease|Genetic Association Studies|Alleles|Haplotype|Asian Continental Ancestry Group|Case-Control Studies|GABRP protein, human|Receptors, GABA-A 40 GABRP 26199913 Cell J 2015 PMC4503848 10.22074/cellj.2016.3756 0 6 0 19 Rats|Animals|*Liver Regeneration|*Cell Transdifferentiation|*Hepatocytes|Kupffer Cells|Liver|Hepatic Stellate Cells|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Hepatectomy|Rats, Sprague-Dawley|Dendritic Cells|*Focal Nodular Hyperplasia|*Genetic Marker|Signal Transduction|Cell Proliferation 40 GAGE1 26298164 Ann. Thorac. Surg. 2015 10.1016/j.athoracsur.2015.05.089 3 0 1 20 *Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|Antigens, Neoplasm|DNA Methylation|Biomarkers, Tumor|Promoter Regions, Genetic|Tumor Suppressor Proteins|*Epigenetic|Epigenesis, Genetic 48 GIMAP4 26596891 BMC Genomics 2015 PMC4657355 10.1186/s12864-015-2174-0 33 0 2 68 Humans|Animals|Cattle|Female|Mice|*Alleles|Sequence Analysis, RNA|Allelic Imbalance|Gene Expression|Gene Expression Profiling|Polymorphism, Single Nucleotide|*Mammal|Chromosome 29 GIMAP4 25993652 PLoS ONE 2015 PMC4437778 10.1371/journal.pone.0127352 6 6 0 68 Rats|Animals|*Non-alcoholic Fatty Liver Disease|Diabetes Mellitus, Type 2|*Biomarkers|*Disease Progression|Liver|Inflammation 29 GIMAP4 25964488 J. Immunol. 2015 PMC4456634 10.4049/jimmunol.1500016 11 0 1 68 Humans|Rats|Animals|Mice|*Diabetes Mellitus, Type 1|*GTPase|Prospective Studies|*Mice, Inbred NOD|*Allergy|*Asthma|Rat, BB|Single Nucleotide Polymorphisms|Genotype|Genetic Predisposition to Disease|Haplotype|Alleles|TYRP1 protein, human|*Membrane Glycoproteins|Genetic Variation|IL2RA protein, human|Interleukin-2 Receptor alpha Subunit|Epistasis, Genetic 29 GLDN 26686025 Bone 2015 10.1016/j.bone.2015.12.005 1 0 0 88 *Calcaneus|Republic of Korea|Genome-Wide Association Study|Genetic Predisposition to Disease|Fracture, Osteoporotic|Polymorphism, Single Nucleotide|Osteoporosis|Genotype|*Foot|*Ankle Injuries 30 GLIPR2 26678074 Inflammation 2015 10.1007/s10753-015-0297-8 2 9 0 52 TLR4 protein, human|*Toll-Like Receptor 4|*Signal Transduction|Myeloid Differentiation Factor 88|lipopolysaccharide B|Lipopolysaccharides|Adaptor Proteins, Vesicular Transport|Toll-Like Receptor 2|*Immunity, Innate|Adaptor Proteins, Signal Transducing|Interferon Regulatory Factor-3|IRAK1 protein, human|Interleukin-1 Receptor-Associated Kinases|Interferon-beta|Type I Interferon|Membrane Glycoproteins|Phosphorylation|Protein Transport 21 glycolisis 26379889 Int J Clin Exp Med 2015 PMC4565272 5 0 0 0 Humans|*Fluorodeoxyglucose F18|*Positron Emission Tomography Computed Tomography|*Esophageal Cancer|Esophageal Squamous Cell Carcinoma|*Chemoradiotherapy|Multimodal Imaging|Positron-Emission Tomography|Tumor Burden|Radiopharmaceuticals|Tomography, X-Ray Computed|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Prognosis|Lymphatic Metastasis|Neoplasm Recurrence, Local|Retrospective Studies 23 glycolisis 25943759 Toxicol. Lett. 2015 10.1016/j.toxlet.2015.04.016 2 0 1 0 Rats|Animals|fipronil|*Energy Metabolism|fipronil sulfone|*Pyrazoles|Gluconeogenesis|Glycolysis|Glycogenolysis|Mitochondria, Liver|Livers|Glucose|Oxygen Consumption|Adenosine Triphosphate|Rats, Wistar|Perfusion|Chain, Respiratory|Fasting|Lactate 23 glycolisis 25929940 Eur Radiol 2015 10.1007/s00330-015-3754-8 8 0 2 0 Humans|*Carcinoma, Non-Small-Cell Lung|*Prognosis|*Lung Neoplasms|Fluorodeoxyglucose F18|Multimodal Imaging|Positron-Emission Tomography|Radiopharmaceuticals|Tumor Burden|Tomography, X-Ray Computed|Neoplasm Staging|Volume CT|Glycolysis 23 glycosis 26464675 Int J Clin Exp Pathol 2015 PMC4583907 12 2 0 0 Humans|*Stomach Neoplasms|*Lymphatic Metastasis|*Pyruvate Kinase|*Hexokinase|*Prognosis|TNM Staging|Adenocarcinoma|Gastric Mucosa|Biomarkers, Tumor|Immunohistochemistry|Stomach|Survival Rate|*Chinese|RNA, Messenger|Western Blotting|Immunoenzyme Techniques|HK1 protein, human 21 GOLGA3 25749990 Hum. Mol. Genet. 2015 10.1093/hmg/ddv085 4 0 0 189 Humans|Cattle|Animals|*Retinitis Pigmentosa|Eye Proteins|Retina|Centrosome|Retinal Photoreceptor Cells|Cilium|Basal Bodies|Mutation|Golgi Apparatus|Microtubule|AKAP9 protein, human|Cytoskeletal Proteins|A Kinase Anchor Proteins|FAM161A protein, human 46 GPR174 26077720 J. Exp. Med. 2015 PMC4493414 10.1084/jem.20141827 9 16 0 18 Mice|Animals|lysophosphatidylserine|*T-Lymphocytes, Regulatory|*Lysophospholipids|Receptors, Lysophospholipid|alpha E integrins|Integrin alpha Chains|Antigens, CD|Receptors, G-Protein-Coupled|Lymphocyte Activation|Cell Proliferation|Experimental Autoimmune Encephalomyelitis|GPR174 protein, mouse 26 GPR174 25970039 J. Med. Chem. 2015 10.1021/jm5020082 6 0 0 18 Humans|lysophosphatidylserine|*Lysophospholipids|Receptors, Lysophospholipid|GPRC5C protein, human|*G-Protein-Coupled Receptors|*Structure-Activity Relationships|Serine, Phosphatidyl|Fatty Acids|HEK293 Cells|GPR174 protein, human 26 GPR179 26396487 Mol. Vis. 2015 PMC4575902 2 1 0 5 Mice|Animals|*Mice, Inbred C3H|Cyclic Nucleotide Phosphodiesterases, Type 6|Electroretinography|*Mutation|Retinal Degeneration|Retinal Rod Photoreceptor Cells|Homozygote|Phenotype|Genotype|Disease Models, Animal|*Survey 25 GPR179 25997951 Eur. J. Neurosci. 2015 PMC4733627 10.1111/ejn.12959 16 4 1 5 Humans|Mice|Animals|*Retinal Cone Photoreceptor Cells|Night blindness, congenital stationary|Night Blindness|Retinal Bipolar Cells|Eye Diseases, Hereditary|Genetic Diseases, X-Linked|Retina|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|Myopia|Dendrites|*Neurogenesis|Synapses|Signal Transduction|TRPM Cation Channels|Mutations|TRPM1 protein, human|Trpm1 protein, mouse 25 GPR179 25613321 Nat Commun 2015 PMC4354202 10.1038/ncomms7006 31 2 7 5 Mice|Animals|Mice, Inbred C57BL|Retinal Degeneration|Cyclic Nucleotide Phosphodiesterases, Type 6|Mice, Inbred C3H|Retinal Rod Photoreceptor Cells|Electroretinography|*Mutation|Receptors, G-Protein-Coupled|*Gene Therapy|GPR179 protein, mouse 25 GPR26 26384023 PLoS ONE 2015 PMC4575141 10.1371/journal.pone.0138463 28 4 1 71 Animals|Cricetinae|CHO Cells|Cricetulus|GPR68 protein, human|*G-Protein-Coupled Receptors|ADGRG1 protein, human|GPR15 protein, human|GPR39 protein, human|GPR32 protein, human|GPR17 protein, human|Receptors, Peptide|Forskolin|Cyclic AMP|Signal Transduction|Gene Expression|Reporter Gene 20 GPR26 26303144 Neuropathology 2015 10.1111/neup.12237 0 0 0 71 Humans|*Intranuclear Inclusion Bodies|polyglutamine|*Peptides|Neurons|Ubiquitin|Cells, Glial|Huntington Disease|Brain|Spinocerebellar Ataxia Type 1|Cytoplasm 20 gpr34 26384023 PLoS ONE 2015 PMC4575141 10.1371/journal.pone.0138463 28 4 1 33 Animals|Cricetinae|CHO Cells|Cricetulus|GPR68 protein, human|*G-Protein-Coupled Receptors|ADGRG1 protein, human|GPR15 protein, human|GPR39 protein, human|GPR32 protein, human|GPR17 protein, human|Receptors, Peptide|Forskolin|Cyclic AMP|Signal Transduction|Gene Expression|Reporter Gene 42 gpr34 25970039 J. Med. Chem. 2015 10.1021/jm5020082 6 0 0 33 Humans|lysophosphatidylserine|*Lysophospholipids|Receptors, Lysophospholipid|GPRC5C protein, human|*G-Protein-Coupled Receptors|*Structure-Activity Relationships|Serine, Phosphatidyl|Fatty Acids|HEK293 Cells|GPR174 protein, human 42 gpr34 25673461 Chin. Med. J. 2015 PMC4836262 10.4103/0366-6999.151114 2 13 1 33 Humans|*Stomach Neoplasms|G-protein-coupled receptor 34|*Receptors, Lysophospholipid|*Stomach|Cell Proliferation|Apoptosis|Cell Movement|Adenocarcinoma|Proto-Oncogene Proteins c-akt|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Prognosis|Real-Time Polymerase Chain Reaction 42 GPR64 26321231 Cell. Signal. 2015 10.1016/j.cellsig.2015.08.015 18 4 1 39 Male|Humans|*Serum Response Element|*Cell Adhesion|HEK293 Cells|G-Protein-Coupled Receptors|Signal Transduction|NF-kappa B|Up-Regulation|Proteolysis|Cell Migration|GPR64 protein, human 28 GPR64 26188515 Biochem. Biophys. Res. Commun. 2015 10.1016/j.bbrc.2015.07.020 22 0 0 39 Humans|Male|Chlorocebus aethiops|Animals|*Receptors, G-Protein-Coupled|Signal Transduction|*Peptides|Amino Acid Sequence|Protein Binding|HEK293 Cells|COS Cells|GPR64 protein, human 28 GPR64 25713288 Pharmacol. Rev. 2015 PMC4394687 10.1124/pr.114.009647 108 0 9 39 *Pharmacology, Clinical|ADGRE5 protein, human|ADGRG1 protein, human|*G-Protein-Coupled Receptors|Signal Transduction|Cell Membrane|CELSR2 protein, human|Cadherins|CELSR1 cadherin, human|Antigens, CD 28 GPR85 26384023 PLoS ONE 2015 PMC4575141 10.1371/journal.pone.0138463 28 4 1 29 Animals|Cricetinae|CHO Cells|Cricetulus|GPR68 protein, human|*G-Protein-Coupled Receptors|ADGRG1 protein, human|GPR15 protein, human|GPR39 protein, human|GPR32 protein, human|GPR17 protein, human|Receptors, Peptide|Forskolin|Cyclic AMP|Signal Transduction|Gene Expression|Reporter Gene 25 GPR85 25780553 Mol Autism 2015 PMC4360946 10.1186/s13229-015-0012-5 5 18 0 29 Humans|Child|*Autism Spectrum Disorder|postsynaptic density proteins|Nerve Tissue Proteins|*Disks Large Homolog 4 Protein|Carrier Proteins|Postsynaptic Density|Membrane Proteins|Mutation|Child Development Disorders, Pervasive|Memory|Brain|*Transcription Factors|Learning 25 GRID1 26683835 BMC Med. Genet. 2015 PMC4683724 10.1186/s12881-015-0259-x 10 1 1 73 Humans|*Genetic Predisposition to Disease|Pakistan|*Obesity|Body Mass Index|*Physical Activity|*Smoking|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genome-Wide Association Study|European Continental Ancestry Group|Lifestyle|Alleles|*Tobacco Smoking|Genotype|Phenotype|Risk Factors 36 GRID1 26597662 Schizophr. Res. 2015 PMC4707095 10.1016/j.schres.2015.11.008 19 10 0 73 Humans|*Endophenotypes|Gene Regulatory Networks|*Schizophrenia|Genetic Predisposition to Disease|SNPs|SLC6A3 protein, human|Dopamine Plasma Membrane Transport Proteins 36 GRID1 26302849 BMC Gastroenterol 2015 PMC4548694 10.1186/s12876-015-0336-9 7 1 1 73 Humans|*Asian Continental Ancestry Group|*Colorectal Cancer|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Stomach Neoplasms|Genotype|*Stomach|Case-Control Studies|Risk Factors|*Colonic Neoplasms|China|PRLHR protein, human|Receptors, G-Protein-Coupled|HSPA12A protein, human|HSP70 Heat-Shock Proteins 36 GRID1 25939814 Hum Brain Mapp 2015 PMC4969622 10.1002/hbm.22824 7 1 2 73 BDNF protein, human|*Brain-Derived Neurotrophic Factor|*cAMP Response Element Binding Protein|*Cues|Brain|Brain Mapping|Functional Neuroimaging|Alcohol Use Disorder|Alcohol Drinking|Magnetic Resonance Imaging|Craving|Alcohol-Related Disorders|Posterior Cingulate|Ethanol|Praecuneus 36 GRID1 25849980 Transl Psychiatry 2015 PMC4462599 10.1038/tp.2015.33 11 8 3 73 Animals|Mice|Pregnancy|Female|lysophosphatidic acid|*Schizophrenia|*Lysophospholipids|*Disease Models, Animal|*Brain|Cortex, Prefrontal|Parvalbumins|Prepulse Inhibition|Prenatal Exposure Delayed Effects|*Problem Behavior|Behavior, Animal|Amfetamine|*Signal Transduction|Dopamine|Hippocampus|*Intracranial Hemorrhages 36 GRIN3B 26031516 J Transl Med 2015 PMC4450850 10.1186/s12967-015-0525-x 11 7 1 31 Sjogren's Syndrome|Autoimmunity|Autoimmune Diseases|Genomics|Genetic Predisposition to Disease|Phenotype 21 GULP1 25981829 Cancer Genet 2015 10.1016/j.cancergen.2015.03.012 6 0 1 148 Female|Humans|Middle Aged|*Meningioma|*Whole Exome Sequencing|SMARCB1 protein, human|*SMARCB1 Protein|*Neurofibromatosis Type II|Meningeal Neoplasms|*Mutations|DNA-Binding Proteins|Transcription Factors|Chromosomal Proteins, Non-Histone|Neurofibromin 2|Neurilemmoma|DNA, Neoplasm|IRS4 protein, human|Insulin Receptor Substrate Proteins 37 H6PD 26528718 PLoS ONE 2015 PMC4631333 10.1371/journal.pone.0141767 2 6 1 587 Male|*Leydig Cells|galactose-6-phosphate dehydrogenase|Carbohydrate Dehydrogenases|*Hepatocytes|11-beta-Hydroxysteroid Dehydrogenase Type 1|Glucose-6-Phosphate|Liver|Monosaccharide Transport Proteins|NADP|*Testis|Cell Line 65 H6PD 26452272 PLoS ONE 2015 PMC4599835 10.1371/journal.pone.0140326 1 3 1 587 Female|Humans|*Polycystic Ovary Syndrome|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|Alleles|Case-Control Studies|11-beta-Hydroxysteroid Dehydrogenase Type 1|HSD11B1 protein, human 65 HEG1 26537538 Anal. Chem. 2015 10.1021/acs.analchem.5b03232 4 0 1 40 Humans|*Chromatography, Liquid|*Proteomics|*Tandem Mass Spectrometry|Mucopolysaccharidoses|*Mucopolysaccharidosis I|Glycosaminoglycans|Dermatan Sulfate|Heparitin Sulfate|Mucopolysaccharidosis II|Mucopolysaccharidosis VI|Keratan Sulfate|*Biomarkers|Mucolipidoses|*Extracellular Matrix 37 HEG1 26095524 Sci Rep 2015 PMC4476092 10.1038/srep11465 9 33 2 40 Humans|Child|Adolescent|*Sarcoma, Ewing|XI-006|TP53 protein, human|*Tumor Suppressor Protein p53|olaparib|*Piperazines|nitrobenzofuroxan|*Oxadiazoles|*Neuroectodermal Tumors, Primitive, Peripheral|Phthalazines|*Apoptosis|Poly(ADP-ribose) Polymerase Inhibitors|Proto-Oncogene Proteins c-mdm2|Cell Cycle Proteins|Antineoplastic Agents|Osteosarcoma|Cell Line, Tumor|Nuclear Proteins 37 HEG1 25771974 Mutat. Res. 2015 10.1016/j.mrfmmm.2014.11.002 11 0 2 40 Humans|Mesothelioma, Malignant|*Mesothelioma|Pleural Neoplasms|*Lung Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Epithelioid Cell|mRNA|Genes, cdc|Transcriptome|TACC1 protein, human|Microtubule-Associated Proteins|Cell Adhesion Molecules|Fetal Proteins|Nuclear Proteins|*Cell Lines 37 HES2 25923331 Epigenetics 2015 PMC4623041 10.1080/15592294.2015.1039216 21 7 2 67 Humans|*Histone Deacetylase Inhibitors|*Azacytidine|Adenocarcinoma Of Esophagus|*Esophageal Cancer|Esophageal Squamous Cell Carcinoma|Hydroxamic Acids|Decitabine|Histone Deacetylases|HDAC1 protein, human|Histone Deacetylase 1|Apoptosis|Cell Line, Tumor|DNA Modification Methylases|Acetylation|DNA Methylation|Cell Proliferation|Viability, Cell|entinostat 55 HES2 25664855 J. Clin. Invest. 2015 PMC4362238 10.1172/JCI79328 52 7 6 67 Humans|Mice|Animals|Endothelial Cells|*Mice, SCID|*Mice, Inbred NOD|*Pluripotent Stem Cells|Hematopoietic Stem Cell|Cell Differentiation|Hematopoiesis|Multipotent Stem Cells|Coculture|Antigens, CD34|Cell Lineage|Blood, Cord|Induced Pluripotent Stem Cells|PTPRC protein, human|Leukocyte Common Antigens|Cells, Cultured|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit 55 HINT2 26077425 Epigenomics 2015 10.2217/epi.14.94 10 1 0 69 *B-DNA|*DNA Methylation|*High-Throughput Nucleotide Sequencing|*cfDNA|Carcinoma, Hepatocellular|Liver Neoplasms|Sequence Analysis, DNA|DNA, Neoplasm|*Plasma|Semiconductors 32 HINT2 25888314 BMC Genomics 2015 PMC4404018 10.1186/s12864-015-1384-9 26 5 3 69 Humans|Sheep|Animals|*Breeding|*Genome|Sheep, Domestic|Genetics, Population|*Chinese|Genetic Variation|Phenotype|Polymorphism, Single Nucleotide 32 HINT2 25826698 Biochem. J. 2015 10.1042/BJ20141568 1 1 0 69 Humans|phosphoramidic acid|fragile histidine triad protein|*Acid Anhydride Hydrolases|*Phosphoric Acids|*Neoplasm Proteins|*Amides|Substrate Specificity|Kinetics|histidine triad protein|Hydrolases|*Catalysis|Dinucleoside Triphosphates|*Nucleosides|Amino Acid Sequence|adenosine 5'-phosphoramidate|Adenosine Monophosphate|Nucleotides|Binding Sites 32 HIVEP2 26483320 Neurosci. Lett. 2015 10.1016/j.neulet.2015.10.037 1 0 0 69 Humans|Animals|Mice|*Mice, Knockout|GRM5 protein, human|Receptor, Metabotropic Glutamate 5|Radiopharmaceuticals|Amfetamine|Positron-Emission Tomography|Brain|Hippocampus|Schizophrenia|Tissue Distribution|Motor Activity|Pyridines|Corpus Striatum|Nitriles 77 HMCN1 26545722 BMC Cancer 2015 PMC4636897 10.1186/s12885-015-1892-7 3 12 1 37 Humans|Animals|*Multiple Myeloma|*Coculture Techniques|*Bone Marrow|Bone Marrow Cell|Mesenchymal Stem Cells|Cell Communication|*Hematopoietic System|B Cells|Cell Line, Tumor|Hematopoietic Stem Cell Transplantation 47 HMCN1 26121316 Lab. Invest. 2015 10.1038/labinvest.2015.80 6 0 1 37 Humans|*Soft Tissue Neoplasms|*Sequencing, RNA|Sarcoma|RNA, Micro|Messenger RNA|Gene Expression Regulation, Neoplastic|*Biomarkers|*Whole Exome Sequencing|*Base Sequence|Downregulation|Schwannoma|Bioinformatic 47 HMCN1 26110643 PLoS ONE 2015 PMC4482254 10.1371/journal.pone.0130688 6 21 1 37 Animals|*Zebrafish|*Mutagenesis, Insertional|Zebrafish Proteins|NRG3 protein, human|*Neuregulins|*Organogenesis|*Morphogenesis|*Signal Transduction|Animal Fins|Gene Expression Regulation, Developmental|TYRP1 protein, human|*Membrane Glycoproteins|Cell Shape|Larvae|ACP5 protein, human|*Tartrate-Resistant Acid Phosphatase 47 HMG20B 25639869 Oncogene 2015 10.1038/onc.2014.446 0 4 0 74 22 HMGN3 26112184 Mol. Cell. Endocrinol. 2015 10.1016/j.mce.2015.05.038 2 8 0 72 Female|Mice|Animals|HMGN3 protein, human|*HMGN Proteins|Decidua|Cells, Stromal|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Uterus|Progesterone|Cell Differentiation|siRNA|Cell Proliferation|RNA, Messenger|Cells, Cultured|Transfection|HMGN3 protein, mouse 28 HMX1 26417040 Development 2015 10.1242/dev.128736 2 0 0 76 Animals|Mice|*Vibrissae|Brainstem|*Face|Trigeminal Nuclei|Ganglion, Trigeminal|Axons|Thalamus|Neurons|Brain|Mandible 47 HMX1 25574057 Invest. Ophthalmol. Vis. Sci. 2015 10.1167/iovs.14-15861 6 0 1 76 Oculoauricular Syndrome|*Eye Abnormalities|Anterior segment mesenchymal dysgenesis|*Retinal Dystrophy|*Ear|*Cataract|Homeodomain Proteins|DNA Mutational Analysis|Transcription Factors|Pedigree|Mutation|Phenotype 47 HMX2 26566760 Am. J. Med. Genet. A 2015 10.1002/ajmg.a.37448 3 0 0 20 Humans|Male|Female|Comparative Genomic Hybridization|Chromosome 10, monosomy 10q|Chromosome Deletion|*Craniosynostosis|Karyotyping|Facies|Intellectual Disability|Genotype-Phenotype Correlations|Phenotype|*Brain|In Situ Hybridization, Fluorescence|Craniofacial Abnormalities|Learning Disabilities|*Chromosome Structures|Chromosomes, Human, Pair 10|*Suture 40 HOOK3 26230842 PLoS ONE 2015 PMC4521853 10.1371/journal.pone.0134614 3 1 1 276 Humans|Male|Neoplasm Recurrence, Local|*Prostate Cancer|Gleason Score|Prostate-Specific Antigen|PTEN protein, human|PTEN Phosphohydrolase|Prostatectomy|Prognosis|Transcriptional Regulator ERG|Immunohistochemistry|*Genomic Instability|Biomarkers, Tumor|Oncogene Proteins, Fusion|Tissue Array Analysis|*Carrier Proteins|Trans-Activators|Adaptor Proteins, Signal Transducing|hook3 protein, human 33 HOOK3 25799409 PLoS ONE 2015 PMC4370497 10.1371/journal.pone.0119423 6 24 0 276 *Amyloid beta-Peptides|*Alzheimer Disease|Amyloid Plaques|Amyloid beta-Protein Precursor|tau Proteins|Neurons|Neuroglia|TYRP1 protein, human|*Membrane Glycoproteins|Astrocytes|Brain|Phosphorylation|Cultured Cells|link protein|Proteoglycans|Extracellular Matrix Proteins 33 HOXA6 26450967 Development 2015 PMC4712882 10.1242/dev.126888 7 0 1 56 Mice|Animals|*Cell Differentiation|Endoderm|Mesoderm|Organogenesis|Pancreas|Islets of Langerhans|Endocrine Cells|Insulin-Secreting Cells|Progenitor Cells|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Cells, Cultured|In Situ Hybridization|Hoxb6 protein, mouse|Hox6 protein, mouse 36 HSPB3 26490709 Sci Rep 2015 PMC4614888 10.1038/srep15174 21 13 2 1045 Humans|Male|Mice|Animals|*Bulbo-Spinal Atrophy, X-Linked|AR protein, human|Androgen Receptor|Muscular Disorders, Atrophic|*Autophagy|*Muscular Atrophy|*Disease Models, Animal|Motoneurons|TRIM63 protein, human|Muscle Proteins|Ubiquitin|Proteasome|polyglutamine|Peptides|Gene Expression Regulation|E3 Ligase|Transcriptional Activation|*Muscle 48 HSPB3 25847151 Neurosci. Lett. 2015 10.1016/j.neulet.2015.04.001 28 6 2 1045 *Mitochondrial Dynamics|Charcot-Marie-Tooth disease, Type 4A|Charcot Marie Tooth Disease|Charcot-Marie-Tooth disease, Type 2K|Charcot-Marie-Tooth disease, Type 2A|Inherited Peripheral Neuropathy|GTP Phosphohydrolases|Mitochondrial Proteins|Mutations|Membrane Proteins|Mitochondria|Hereditary Sensory and Autonomic Neuropathies|Axonal Transport|Nerve Tissue Proteins|Heterozygote|Axons|Nerves, Peripheral|Phenotype 48 HSPB3 25842858 Mol. Biol. (Mosk.) 2015 0 0 0 1045 Humans|Animals|Mice|*Catalepsy|*Chromosomes, Human, Pair 13|*CBA Mice|Mice, Congenic|*Genotype|IL6ST protein, human|Cytokine Receptor gp130|Brain|Chromosomes, Mammalian|Gene Expression|Genetic Predisposition to Disease|AKR Mice|Substantia Nigra|peptide MB-35|*Peptides|Corpus Striatum|Ndufs4 protein, mouse|Electron Transport Complex I 48 HSPB3 25798051 Int J Med Sci 2015 PMC4366630 10.7150/ijms.10735 34 4 5 1045 Humans|*Carcinoma, Hepatocellular|*Hepatitis B virus|*Liver Neoplasms|*Up-Regulation|*Heat Shock Proteins|Prognosis|Gene Expression Regulation, Neoplastic|Neoplasm Staging|*Transcriptional Activation|Proportional Hazards Models|HSPA12A protein, human|HSP70 Heat-Shock Proteins|HSPA4 protein, human|HSP110 Heat-Shock Proteins 48 ICA1 26578562 Nucleic Acids Res. 2015 PMC4678817 10.1093/nar/gkv1099 5 5 1 128 Humans|*Transcriptome|*RNA Splicing|Sequence Analysis, RNA|Sequence Alignment|*Genomes|RNA Splice Sites|Alternative Splicing|Software|Gene Expression Profiling|Algorithms|Genomics|Whole Exome Sequencing|Polymorphism, Single Nucleotide 106 ICA1 26493241 Br. J. Pharmacol. 2015 PMC5341225 10.1111/bph.13369 2 1 0 128 Rats|Animals|murrayafoline A|*Molecular Docking Simulation|*Alkaloids|carbazole|*Carbazoles|Muscle, Smooth, Vascular|Myocytes, Smooth Muscle|Calcium Channels, L-Type|*Electrophysiological Phenomena|Vasodilator Agents|Calcium Channel Blockers|Vasodilation|*Myocytes|Muscle Contraction|Patch-Clamp Techniques 106 ICA1 26306493 J. Cell. Sci. 2015 10.1242/jcs.173534 11 1 0 128 Humans|Male|Mice|Animals|*Acrosome|*Spermiogenesis|Infertility, Male|Sperm|Globozoospermia|Mice, Knockout|Carrier Proteins|Nuclear Proteins|Spermatids|Cell Cycle Proteins|ICA1 protein, human|Autoantigens|Sperm Number|Protein Transport|*Adaptor Proteins, Signal Transducing|Golgi Apparatus|Cell Nucleus|PICk1 protein, human 106 ICA1 26031516 J Transl Med 2015 PMC4450850 10.1186/s12967-015-0525-x 11 7 1 128 Sjogren's Syndrome|Autoimmunity|Autoimmune Diseases|Genomics|Genetic Predisposition to Disease|Phenotype 106 ICA1 25951176 PLoS Genet. 2015 PMC4423873 10.1371/journal.pgen.1005085 13 0 4 128 *Arabidopsis|*Temperature|Arabidopsis Proteins|Gene Expression Regulation, Plant|Genes, Plant|*Cell Proliferation|Plant Leaves|*Hot Temperature|Plants, Genetically Modified|Mutations|Alleles|Phenotype|ICA1 protein, Arabidopsis|Nucleotidyltransferases 106 IGLL5 26638776 Nat Commun 2015 PMC4686820 10.1038/ncomms9866 53 3 3 24 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|Cytidine Deaminase|Immunoglobulin Variable Region|Immunoglobulin Heavy Chains|*Sequencing, Whole Genome|Mutation|B-Lymphocytes|RNA, Neoplasm|RNA, Messenger 21 IGLL5 26524200 Cancer Cytopathol 2015 PMC5296944 10.1002/cncy.21629 3 0 1 24 Immunoglobulin lambda-Chains|*B-Lymphocytes|Immunoglobulin kappa-Chains|In Situ Hybridization|Lymphoma, B-Cell|Immunoglobulin Light Chains|Hybrid-B|*Plasminogen Activators|Clone Cells|RNA, Messenger 21 IGLL5 26311227 World J Surg Oncol 2015 PMC4551378 10.1186/s12957-015-0642-2 9 0 1 24 Humans|*Sentinel Lymph Node|*RNA|Carcinoma, Ductal, Breast|Carcinoma, Lobular|Sentinel Lymph Node Biopsy|Lymph Node Excision|Lymph Nodes|Lymphatic Metastasis|Axilla|Neoplasm Staging|Prognosis|Neoplasm Invasiveness|*Sequencing, Next-Generation|*Breast Neoplasms|*Biomarkers|Sequence Analysis, RNA 21 IGLL5 26136121 J. Periodontol. 2015 10.1902/jop.2015.150175 1 0 0 24 Humans|*Aggressive Periodontitis|*Gene Regulatory Networks|*Gene Expression Profiles|Gingiva|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Computational Biology|Up-Regulation 21 IGSF11 26595655 Nat. Neurosci. 2015 PMC5010778 10.1038/nn.4176 11 16 0 18 Mice|Animals|*Synaptic Transmission|AMPA Receptors|PSD-95 Protein|Synapses|Hippocampus|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Neuronal Plasticity|Long-Term Potentiation|Neurons|Protein Transport|Glutamate 27 IGSF11 26472973 J Breast Cancer 2015 PMC4600687 10.4048/jbc.2015.18.3.235 18 3 1 18 Female|Rats|Animals|*RNA, Circular|*Lactation|Sequence Analysis, RNA|MicroRNAs 27 IGSF11 26227905 Mol. Neurobiol. 2015 10.1007/s12035-015-9331-y 4 0 1 18 Humans|United States|*Genome-Wide Association Study|*Parkinson Disease|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Genetic Loci|Ethnic Groups|Case-Control Studies|PRDM2 protein, human|Nuclear Proteins|DNA-Binding Proteins|Histone-Lysine N-Methyltransferase|Transcription Factors|PDE10A protein, human|Phosphoric Diester Hydrolases 27 ILDR1 26226137 Genet. Med. 2015 PMC4733433 10.1038/gim.2015.89 41 0 2 64 *Whole Exome Sequencing|Nonsyndromic Deafness|*Exome|Deafness, Autosomal Recessive|*Hearing Loss, Sensorineural|Deafness|Connexin 26|Connexins|Genes, Recessive|Mutations|Pedigree|*Cohort Studies 35 ILDR1 25822906 PLoS ONE 2015 PMC4378975 10.1371/journal.pone.0120674 11 8 1 64 Humans|Mice|Animals|*Tight Junctions|*Membrane Protein|*Cochlear Hair Cell|Deafness, Autosomal Recessive 42|Hearing Loss, Sensorineural|Deafness, Autosomal Recessive 49|Deafness|Tricellulin|Cells, Epithelial|Hearing|Mice, Knockout|Mutations|ILDR1 protein, human|Receptors, Cell Surface|Ildr1 protein, mouse 35 IMPG1 25681578 Prog Retin Eye Res 2015 10.1016/j.preteyeres.2015.02.001 12 0 2 26 Adult|Humans|*Vitelliform Macular Dystrophy|Fluorescein Angiography|Coherence Tomography, Optical|Retinal Pigment Epithelium|Visual Acuity|Phenotype|Eye Proteins|Electrooculogram|Retrospective Studies|Vision Disorders|Mutation|Single Nucleotide Polymorphism|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1|BEST1 protein, human|Bestrophins 29 INSL4 26430762 PLoS ONE 2015 PMC4591983 10.1371/journal.pone.0139342 0 21 1 17 *Endothelial Cells|*Wound Healing|Stimulators, Angiogenesis|Rehmannia|Astragalus Plant|Cell Migration|Neovascularization, Physiologic|Diabetic Foot|Drugs, Chinese Herbal|Cell Proliferation|Phytotherapy|Signal Transduction|*Neovascularization, Pathologic|Cell Line|*Morphogenesis 45 insl6 26355908 Mutat. Res. 2015 10.1016/j.mrfmmm.2015.08.006 3 0 0 28 Humans|*Metal-on-Metal Joint Prostheses|*Arthroplasty, Replacement, Hip|Hip Prosthesis|Hip Joint|*Metals|Cobalt|Chromium|Prosthesis Failure|Prosthesis Design|Ions|*Mutation 40 insl6 25877373 J. Assist. Reprod. Genet. 2015 PMC4491072 10.1007/s10815-015-0474-6 7 0 1 28 Male|Humans|Sperm Tail|Infertility, Male|*DNA Mutational Analysis|Spermatozoa|Sequencing, Whole Exome|Dyneins|Mutation 40 INSRR 26322622 Biochemistry 2015 10.1021/acs.biochem.5b00805 11 1 1 284 INSR protein, human|*Receptor, Insulin|Diabetes Mellitus, Type 2|*Signal Transduction|*Antigens, CD|Receptor, IGF Type 1|Insulin|Phosphorylation|Protein Binding|Insulin-Like Growth Factor I 86 INSRR 26154399 J. Neurosci. Res. 2015 10.1002/jnr.23621 1 0 0 284 Animals|Ion Channel Gating|Patch-Clamp Techniques|Acid Sensing Ion Channels|Transient Receptor Potential Channels|Hydrogen-Ion Concentration|Connexins|Gap Junctions|Neurons|Guanylyl Cyclase 86 INSRR 26085948 Acta Naturae 2015 PMC4463416 3 1 0 284 Humans|Animals|INSR protein, human|insulin receptor-related receptor|*Receptor, Insulin|*Alkali|*Computational Biology|Protein Structure, Tertiary|Phosphorylation|Signal Transduction|Antigens, CD|IGF1R protein, human|*Complement Factor B|FN1 protein, human|Fibronectin|HEK293 Cells|Hydrogen-Ion Concentration 86 INSRR 26072449 Growth Horm. IGF Res. 2015 10.1016/j.ghir.2015.06.004 0 1 0 284 Animals|*Insulin|*New World Monkeys|insulin receptor-related receptor|Insulin Receptor|IGF1R protein, human|Receptors, Somatomedin|IGF1 protein, human|Insulin-Like Growth Factor I|IGF-Binding Proteins|IGF2 protein, human|IGF-2|INSR protein, human|IGFBP1 protein, human|Insulin-Like Growth Factor Binding Protein 1|*Insulin, Regular, Human|Receptor, IGF Type 1|Receptor, Mannose 6 Phosphate|*Cebidae 86 INSRR 25597417 Biochimie 2015 10.1016/j.biochi.2014.12.014 4 4 0 284 INSR protein, human|insulin receptor-related receptor|*Receptor, Insulin|FN1 protein, human|*Fibronectins|*Alkali|Phosphorylation|Protein Structure, Tertiary|Protein Binding|Signal Transduction|Antigens, CD|Kinase|Hydrogen-Ion Concentration 86 IPO7 26525414 Mol. Cell. Endocrinol. 2015 PMC4684427 10.1016/j.mce.2015.10.016 6 21 0 322 Humans|*Active Transport, Cell Nucleus|*Thyroid Hormone Receptor|HeLa Cells|KPNB1 protein, human|*beta Karyopherins|Importins|Nuclear Localization Signals|alpha Karyopherins|Cell Nucleus|Cytoplasm|Protein Transport|Protein Binding|Green Fluorescent Proteins 55 IPO7 26085085 J. Biol. Chem. 2015 PMC4513123 10.1074/jbc.M115.662882 6 9 1 322 Mice|Humans|Animals|Hedgehog Proteins|*Glioblastoma|Zinc Finger Protein GLI1|Signal Transduction|Forkhead Box Protein M1|Gene Expression Regulation, Neoplastic|Cell Proliferation|Forkhead Transcription Factors|Promoter Regions, Genetic|Glioma|siRNA|Karyopherins|FOXM1 protein, human 55 IPO7 25934513 J Ethnopharmacol 2015 10.1016/j.jep.2015.04.013 8 9 3 322 Animals|*Carcinoma, Hepatocellular|*Salvia miltiorrhiza|*Liver Neoplasms|*Astragalus Plant|SMAD2 protein, human|Smad2 Protein|dan-shen root extract|*Drugs, Chinese Herbal|Smad Proteins|Diethylnitrosamine|Astragalus membranaceus|Fibrosis, Liver|Phosphorylation|Signal Transduction|Transforming Growth Factor beta|Hep G2 Cells|Transforming Growth Factor beta1|Plasminogen Activator Inhibitor 1 55 IRGC 26686152 Carbohydr Polym 2015 10.1016/j.carbpol.2015.11.008 2 0 0 17 *Amylopectin|*Oryza|Starch|Amylose|Cooking|Molecular Weight|*Food Hypersensitivity|Gelatin 32 IRGC 25705117 Mol. Breed. 2015 PMC4328105 10.1007/s11032-015-0276-7 24 0 4 17 *Oryza|*Genotype|Chromosome Mapping|Chromosomes, Plant|Quantitative Trait Loci|Crosses, Genetic|Genome, Plant|Breeding|Microsatellite Repeats|Phenotype 32 IRX4 26651608 Stem Cell Reports 2015 PMC4682289 10.1016/j.stemcr.2015.10.021 5 7 1 60 Mice|Animals|*Myocytes, Cardiac|*Embryonic Stem Cells|*Heart Ventricles|Cell Separation|Induced Pluripotent Stem Cells|Cell Differentiation|Cell Line|Action Potentials|mRNA|Flow Cytometry|Electrophysiological Phenomena|Biomarkers|Gene Expression Regulation|Transcription Factor|Irx4 protein, mouse|Homeodomain Proteins 63 IRX4 25560799 Oral Oncol. 2015 10.1016/j.oraloncology.2014.12.012 14 0 2 60 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|Lymphatic Metastasis|Prognosis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Cohort Studies|Singapore 63 ISL2 26402608 Neuron 2015 PMC4583656 10.1016/j.neuron.2015.08.030 13 5 1 74 Animals|Mice|*Cues|Superior Colliculus|Visual Pathways|LIM-Homeodomain Proteins|Receptor, EphA3|Retina|Retinal Ganglion Cells|Brain Mapping|Axons|Transcription Factors 55 ISL2 25935106 J. Allergy Clin. Immunol. 2015 PMC4562879 10.1016/j.jaci.2015.03.030 9 0 2 74 Child|Humans|Adult|*Genome-Wide Association Study|*Dermatitis, Atopic|Republic of Korea|Genetic Predisposition to Disease|*Eczema|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Asian Continental Ancestry Group|Genotype|Case-Control Studies|Immunoglobulin E 55 ISL2 25843547 Exp. Neurol. 2015 PMC4446133 10.1016/j.expneurol.2015.03.024 14 8 2 74 Chick Embryo|Mice|Animals|*Semaphorin|*Neural Tube|*Transcription Factors|*Cell Body|*Motor Neuron|*Signal Transduction|Axons|Spinal Cord|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Cell Movement 55 ISM1 26364800 Acta Pharmacol. Sin. 2015 PMC4648174 10.1038/aps.2015.73 15 81 1 121 *Angiogenesis Inhibitors|Neovascularization, Pathologic|Cancer 26 ITIH5 26252352 Epigenetics 2015 PMC4844218 10.1080/15592294.2015.1078049 13 0 2 60 Humans|Carcinoma, Non-Small-Cell Lung|Lung Cancer|*Adenocarcinoma|DNA Methylation|Prognosis|Promoter Regions, Genetic|Biomarkers, Tumor|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Proteinase Inhibitory Proteins, Secretory|mRNA|ITIH5 protein, human 37 ITIH5 25861810 Hum. Mol. Genet. 2015 10.1093/hmg/ddv124 90 0 13 60 Male|Female|Humans|*DNA Methylation|*Glycated Hemoglobin A|Diabetes Mellitus, Type 2|*Body Mass Index|CpG Islands|*Adipose Tissue|*Epigenetic|Epigenesis, Genetic|Obesity|*Biomarkers|Promoter Regions, Genetic|Genome-Wide Association Study|RNA, Messenger|ITIH5 protein, human|Proteinase Inhibitory Proteins, Secretory|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 37 ITIH5 25853553 PLoS ONE 2015 PMC4390373 10.1371/journal.pone.0123601 3 1 0 60 *Adipokines|Serpin E2|Knee Joint|Osteoarthritis, Knee|Adipose Tissue|Patella|Synovium|Chondrocytes 37 ITIH5 25809190 Exp. Dermatol. 2015 10.1111/exd.12704 6 0 0 60 Humans|Mice|Animals|*Mice, Knockout|*Trypsin Inhibitors|*Epidermis|*Skin|Keratinocytes|Proteinase Inhibitory Proteins, Secretory|alpha-1-microglobulin|Alpha-Globulins|Gene Expression Regulation, Neoplastic|Down-Regulation|*Dermatitis|Hyaluronan|RNA, Messenger|Cells, Cultured|ITIH5 protein, human 37 ITM2A 26691219 Gynecol. Oncol. 2015 10.1016/j.ygyno.2015.12.006 6 9 0 90 Humans|Female|*Carcinoma, Ovarian Epithelial|*Prognosis|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|*G2 Cell Cycle Arrest|Carboplatin|Paclitaxel|Antineoplastic Combined Chemotherapy Protocols|Drug Resistance, Neoplasm|Neoplasm Staging|Neoplasm Grading|Cell Line, Tumor|Biomarkers, Tumor|Kaplan-Meier Estimate|ITM2A protein, human|Membrane Proteins 47 ITM2A 26323392 BMC Med. Genet. 2015 PMC4593198 10.1186/s12881-015-0220-z 3 1 1 90 Male|Humans|*Cleft Palate|*Intellectual Disability|Cleft Lip|*Chromosome 1|Chromosome Deletion|Comparative Genomic Hybridization|Chromosomes, Human, X|Genes, X-Linked|*Hearing Impairment|Pedigree|*Disabled Persons|Growth Hormone 47 ITM2A 26125709 Genet. Mol. Res. 2015 10.4238/2015.May.18.6 2 0 1 90 Humans|*Spondylitis, Ankylosing|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Transcriptome|Molecular Sequence Annotation|Databases, Genetic|Gene Expression Regulation|Case-Control Studies|Upregulation|ITM2A protein, human|Membrane Proteins|MRPS11 protein, human|Ribosomal Proteins|Mitochondrial Proteins 47 ITM2A 25951193 Autophagy 2015 PMC4509440 10.1080/15548627.2015.1034412 10 60 1 90 Animals|*Vacuolar Proton-Translocating ATPases|*Integral Membrane Protein|*Autophagy|Signal Transduction|Cyclic AMP-Dependent Protein Kinases|Lysosomes|Cyclic AMP|Cyclic AMP Response Element-Binding Protein|Autophagosomes|Promoter Regions, Genetic|Transcription, Genetic|Forskolin|Phosphorylation 47 ITM2C 26578816 Biochem. J. 2015 10.1042/BJ20150920 7 3 1 80 Humans|*Proteins, Amyloidogenic|Amyloid|Amyloid beta-Peptides|Peptide Fragments|Pulmonary Surfactant-Associated Protein C|Amyloidosis|*Inclusion Bodies 27 ITM2C 26515131 Cell. Signal. 2015 10.1016/j.cellsig.2015.10.012 3 19 0 80 Animals|Rats|*Phosphoproteins|TYRP1 protein, human|Membrane Glycoproteins|Amyloid beta-Protein Precursor|Alzheimer Disease|Amyloid|Membrane Proteins|Amyloidogenic Proteins|Protein Phosphatase 1|Neurons|Phosphorylation|Brain|Signal Transduction|Golgi Apparatus|Mutation 27 ITM2C 26384369 G3 (Bethesda) 2015 PMC4632064 10.1534/g3.115.021345 21 0 2 80 Humans|Middle Aged|*DiGeorge Syndrome|MicroRNAs|RNA-Binding Proteins|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Schizophrenia|*Marfan Syndrome|*Craniosynostoses|Psychotic Disorder|*Sequencing, Whole Genome|Chromosome Deletion|Genome|Phenotypes|Cohort Studies 27 KIAA0196 26572744 Orphanet J Rare Dis 2015 PMC4647479 10.1186/s13023-015-0359-x 6 4 1 71 Humans|Mice|Animals|*Spastic Paraplegia, Hereditary|*Mutations|KIAA0196 protein, human|Proteins|Pedigree|Asian Continental Ancestry Group 35 KLK15 26224476 Tumour Biol. 2015 10.1007/s13277-015-3802-7 5 0 0 19 Humans|*Prognosis|*Stomach Neoplasms|*Tissue Kallikreins|KLK15 protein, human|Kallikrein B'|trypsin-like serine protease|Lymphatic Metastasis|Cancer Biomarkers|Immunohistochemistry|Gene Expression Regulation, Neoplastic|RNA, Messenger 53 KLK15 25964550 Anticancer Res. 2015 0 0 0 19 Dogs|Animals|*Kallikrein|*Alternative Splicing|trypsin-like serine protease|Base Sequence|Amino Acid Sequence 53 KLK15 25833159 Biol. Reprod. 2015 PMC4645984 10.1095/biolreprod.114.126136 6 8 0 19 Female|Rats|Animals|*Ovary|*Rats, Sprague-Dawley|afimoxifene|*Tamoxifen|*Ovarian Follicle|Selective Estrogen Receptor Modulators|*Cyclophosphamide|IGF1 protein, human|IGF-1|*Apoptosis|Receptor, IGF-I|Antineoplastic Agents|Fertility|Doxorubicin|Protective Agents 53 KLK15 25563717 Innate Immun 2015 10.1177/1753425914566083 7 10 0 19 Humans|*Neutrophils|KLK15 protein, human|*Kallikrein|Tissue Kallikreins|Kinins|mRNA|KLK6 protein, human|KLK13 protein, human|KLK10 protein, human|Humans|*Neutrophils|KLK15 protein, human|*Kallikrein|Tissue Kallikreins|Kinins|mRNA|KLK6 protein, human|KLK13 protein, human|KLK10 protein, human 53 KLK9 25563717 Innate Immun 2015 10.1177/1753425914566083 7 10 0 20 Humans|*Neutrophils|KLK15 protein, human|*Kallikrein|Tissue Kallikreins|Kinins|mRNA|KLK6 protein, human|KLK13 protein, human|KLK10 protein, human|Humans|*Neutrophils|KLK15 protein, human|*Kallikrein|Tissue Kallikreins|Kinins|mRNA|KLK6 protein, human|KLK13 protein, human|KLK10 protein, human 36 KLK9 26469898 Medicine (Baltimore) 2015 PMC4616806 10.1097/MD.0000000000001617 1 2 1 20 Humans|Rats|Animals|*Hypertension|Kidney|Angiotensin-Converting Enzyme Inhibitors|Kidney Diseases|Blood Pressure|KLK6 protein, human|Kallikrein|*Urinary Tract|Cardiac Hypertrophy|*Cardiovascular System 36 KLK9 26231762 BMC Cancer 2015 PMC4521496 10.1186/s12885-015-1566-5 9 12 1 20 Humans|Male|Female|*Prognosis|KLK6 protein, human|*Kallikreins|kallikrein-related peptidase 3, human|*Grade III Astrocytoma|Immunohistochemistry|Biomarkers, Tumor|Ovarian Neoplasms|Prostate Specific Antigen 36 KLK9 25897967 BMC Genomics 2015 PMC4405864 10.1186/s12864-015-1508-2 22 2 4 20 Humans|*Psoriasis|Skin|Transcriptome Analysis|Keratinocytes|RNA, Messenger|IL36RN protein, human|Interleukins 36 KLLN 26673699 Nucleic Acids Res. 2015 PMC4856962 10.1093/nar/gkv1481 7 18 1 121 Humans|Heterochromatin|*Genomic Stability|Histone-Lysine N-Methyltransferase|DNA Methylation|Histones|Cowden Syndrome|PTEN protein, human|PTEN Phosphohydrolase|Repressor Proteins 31 KLRC4 26347074 J. Autoimmun. 2015 PMC4628864 10.1016/j.jaut.2015.08.013 41 9 3 16 Genome-Wide Association Study|*Immunogenetics|HLA-B51 Antigen|Genetic Predisposition to Disease|STAT4 Transcription Factor|Alleles|Polymorphism, Single Nucleotide|Behcet Syndrome|IL23R protein, human|Receptors, Interleukin|Haplotype|Genes, MHC Class I|Aminopeptidases|Minor Histocompatibility Antigens|Genotype|Case-Control Studies|HLA-B|Receptors, CCR1 24 KLRC4 26097239 2015 10.1002/art.39240 10 0 0 16 Humans|Genome-Wide Association Study|Iran|*STAT4 Transcription Factor|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Behcet Syndrome|Genotype|Asian Continental Ancestry Group|Case-Control Studies|ERAP1 protein, human|Aminopeptidases|Minor Histocompatibility Antigens|STAT4 protein, human|KLRC4 protein, human|NK Cell Lectin-Like Receptor Subfamily C|CCR1 protein, human|Receptors, CCR1 24 LACRT 26670139 Sci Rep 2015 PMC4680935 10.1038/srep18362 2 24 1 69 Humans|*Lipopolysaccharides|Corneal Epithelium|Dry Eye|*Epithelial Cells|Lacrimal Glands|Cornea|Eye Proteins|Keratitis|Cells, Cultured|*Cell Death|Cyclooxygenase 2 27 LACRT 26318608 Exp. Eye Res. 2015 PMC4698016 10.1016/j.exer.2015.08.015 7 37 0 69 Tears|Dry Eye|Glycoproteins|Eye Proteins|Cornea|*Autophagy|Conjunctiva|transglutaminase 2|GTP-Binding Proteins|Corneal Diseases|Transglutaminases|SDC1 protein, human|Syndecan-1|Cytokines 27 LAD1 26639818 Hum. Immunol. 2015 10.1016/j.humimm.2015.11.019 1 0 0 596 Humans|Leukocyte adhesion deficiency type 1|Iran|*Leukocyte-Adhesion Deficiency Syndrome|CD18 Antigens|Genetic Testing|DNA Mutational Analysis|Mutation|Mutation, Missense|PCR 84 laptm5 25998573 Biochem. Genet. 2015 10.1007/s10528-015-9682-0 0 0 0 113 Humans|Animals|Mice|Leukocytes, Mononuclear|*Chinese|*Lupus Erythematosus, Systemic|Frequencies, Allele|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Haplotype|Alleles|LAPTM5 protein, human|*Membrane Proteins|Lupus Nephritis|Restriction Fragment Length Polymorphism|Case-Control Studies|Lysosomes 49 laptm5 25928846 BMC Genomics 2015 PMC4434520 10.1186/s12864-015-1445-0 10 12 2 113 RUNX1 Translocation Partner 1 Protein|Core Binding Factor Alpha 2 Subunit|Oncogene Proteins, Fusion|Chromosomal Translocation|Leukemia, Myeloid, Acute|NCOR1 protein, human|*Nuclear Receptor Co-Repressor 1|Hematopoiesis|Cell Differentiation|Cell Line, Tumor|Protein Binding|Promoter Regions, Genetic 49 LARP6 26501340 Biomolecules 2015 PMC4693254 10.3390/biom5042701 25 42 4 495 Ribonucleoproteins|mRNA Translation|Autoantigens|RNA, Messenger|Protein Binding|*Ku Autoantigen|Models, Molecular|*Cancer 35 LARP6 26247836 Genes Immun. 2015 10.1038/gene.2015.31 3 1 0 495 Humans|*Synoviocytes|*TNF-Related Apoptosis-Inducing Ligand|*Rheumatoid Arthritis|*Fibroblasts|Synovial Membrane|Apoptosis|Cell Proliferation|RNA, Small Interfering|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|Signal Transduction|Transfection|Cells, Cultured|Cell Death 35 LARP6 25989359 J. 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Res. 2015 PMC5025301 10.1002/jor.22944 11 3 1 495 Mice|Animals|Quantitative Trait Locus|Mice, Inbred Strains|Crosses, Genetic|Single Nucleotide Polymorphism|Genetic Susceptibility|Phenotypes|Genotype|*Knee Injuries|Meniscus, Medial|KIF26B protein, mouse|Kinesin|Stab2 protein, mouse|Cell Adhesion Molecules, Neuronal|Myo1e protein, mouse|Myosins 35 LARP6 25896032 Biomol NMR Assign 2015 PMC4568005 10.1007/s12104-015-9605-3 0 1 0 495 Humans|Ribonucleoproteins|RNA Binding Protein|Autoantigens|Amino Acid Sequence|Amino Acid Motifs|RRM1 protein, human|Tumor Suppressor Proteins 35 LARP6 25692237 RNA Biol 2015 PMC4615758 10.1080/15476286.2014.996467 11 24 2 495 *Collagen Type I|*mRNA|Ribonucleoproteins|5'UTRs|*Collagen|Autoantigens|Nucleic Acid Conformation|Protein Binding 35 LGALS12 25953264 Tumour Biol. 2015 10.1007/s13277-015-3513-0 4 0 0 461 Adult|Humans|*Galectins|*Leukemia, Myeloid, Acute|Prognosis|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Biomarkers, Tumor|Quantitative Real Time Polymerase Chain Reaction|MicroRNAs|RNA, Messenger|Survival Rate|Neoplasm Staging|Mutation|LGALS4 protein, human|Galectin 4 24 LHX5 26578897 Front Neuroanat 2015 PMC4621302 10.3389/fnana.2015.00136 0 9 1 58 Mice|Animals|*Genes, Homeobox|*Mammillary Bodies|Prospective Studies|LIM-Homeodomain Proteins|Homeodomain Proteins|Transcription Factor|*Neurogenesis|Xenopus Proteins|Gene Expression Regulation, Developmental|Prosencephalon|Nerve Tissue Proteins|Mice, Knockout|Foxb1 protein, mouse|Forkhead Transcription Factors|Lhx9 protein, mouse|Lhx2 protein, mouse 61 LHX5 26321924 Front Neuroanat 2015 PMC4536661 10.3389/fnana.2015.00113 2 16 1 58 Mice|Animals|Hedgehog Proteins|LIM-Homeodomain Proteins|*Cell Differentiation|Transcription Factor|Homeodomain Proteins|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Cell Lineage|Neurons|Hypothalamus 61 LHX5 26147098 PLoS ONE 2015 PMC4492605 10.1371/journal.pone.0132525 1 6 0 58 Animals|*Zebrafish|Zebrafish Proteins|*Prosencephalon|*Sequences, Conserved|LIM-Homeodomain Proteins|Homeodomain Proteins|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Enhancer Elements, Genetic|Transcription Factors|Reporter Gene|Lhx5 protein, zebrafish 61 LHX5 25673852 J. Neurosci. 2015 PMC6605615 10.1523/JNEUROSCI.2699-14.2015 5 0 1 58 *Axon Guidance|*Hindbrain|*Interneurons|LIM-Homeodomain Proteins|Axons|Transcription Factors|*Neurotransmitter|Homeodomain Proteins|Synapses|Gene Expression Regulation, Developmental|Spinal Cord|Nerve Tissue Proteins|Neurons|Mesencephalon|Cerebellum|Brain|*Phenotype 61 LHX5 25591928 Cell Res. 2015 PMC4650575 10.1038/cr.2015.6 15 0 3 58 *Cellular Reprogramming|POU5F1 protein, human|Octamer Transcription Factor-3|Nanog Homeobox Protein|Induced Pluripotent Stem Cells|Embryonic Stem Cells|Homeodomain Proteins|Cell Differentiation|Cell Line|Cells, Cultured|Fibroblasts 61 LIM2 25871839 J. Clin. Endocrinol. Metab. 2015 PMC4454798 10.1210/jc.2014-4484 5 0 0 80 Humans|Combined Pituitary Hormone Deficiency|*Hypopituitarism|LIM-Homeodomain Proteins|*Mutation|Transcription Factors|Homeodomain Proteins|Heterozygote|Gland, Pituitary|Pedigree|Mutation, Missense|Amino Acid Sequence|LHX4 protein, human 116 LIM2 25805458 Neurosci. Lett. 2015 10.1016/j.neulet.2015.03.041 1 0 1 80 Animals|Mice|*Neurogenesis|*Spinal Cord|Neural Stem Cells|Motor Neurons|Cell Differentiation|Astrocytes|NES protein, human|Nestin|Cell Culture Techniques|Cells, Cultured|Cell Separation|Interneurons 116 LIMA1 26350886 Cancer Metastasis Rev. 2015 PMC4661189 10.1007/s10555-015-9595-8 6 24 1 489 Humans|Male|*Actins|Cell Migration|Cytoskeletal Proteins|Neoplasm Proteins|Signal Transduction|TYRP1 protein, human|*Membrane Glycoproteins|Gene Expression Regulation, Neoplastic|Prostate|Prostatic Neoplasms 43 LIMA1 26206181 J Proteomics 2015 10.1016/j.jprot.2015.07.010 4 1 2 489 Humans|*Proteomics|Tandem Mass Spectrometry|Cellular Senescence|*DNA Replication|Downregulation|RNA Interference|histone H3 trimethyl Lys4|Histones|Fibroblasts|Gene Expression Profiling|Cell Line|mRNA 43 LIMA1 25884336 BMC Cancer 2015 PMC4407711 10.1186/s12885-015-1283-0 11 6 3 489 Humans|Adult|Female|Granulosa cell tumor of the ovary|*Granulosa Cell Tumor|*Comparative Genomic Hybridization|*Transcriptome|Forkhead Box Protein L2|Tumors, Sex Cord-Stromal|*Transcriptome Analyses|Ovarian Neoplasms|Forkhead Transcription Factors|Mutations|Point Mutation|Gene Expression Regulation|Genomics 43 LIMA1 25609711 J. Cell. Sci. 2015 10.1242/jcs.163113 15 2 4 489 Dogs|Animals|FLNA protein, human|Filamin A|Cell Transformation, Neoplastic|Cell Communication|Signal Transduction|Epithelium|Protein Kinase A|Cytoskeletal Proteins|Cell Line, Transformed|Myosin II|Carcinogenesis|Madin Darby Canine Kidney Cells 43 LIMA1 25609703 J. Cell. Sci. 2015 PMC4342583 10.1242/jcs.162545 6 3 1 489 Mice|Animals|*Focal Adhesions|PDLIM4 protein, human|*LIM Domain Proteins|LIMS1 protein, human|*Adaptor Proteins, Signal Transducing|*Membrane Proteins|*Cell Adhesion|*Integrins|integrin-linked kinase|Protein-Serine-Threonine Kinases|DNA-Binding Proteins|Microfilament Proteins|Signal Transduction|Cell Movement|FN1 protein, human|Fibronectin 43 LIMA1 25569716 Nat Commun 2015 10.1038/ncomms6908 14 5 3 489 *Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein|*Lymphoma, B-Cell, Marginal Zone|Translocation, Genetic|*Oncogenes|Oncogene Proteins, Fusion|*Oncogenesis|Signal Transduction|Apoptosis|Tumor Suppressor Proteins|*Genes, Tumor Suppressor 43 Lingo2 26644202 Pharmacogenomics J. 2015 10.1038/tpj.2015.84 2 2 0 36 Humans|*Fatty Acids, Nonesterified|*Potassium|B-insulin|Insulin|Glucose|Syndromes, Acute Coronary|Cardioplegic Solutions|Myocardium|Electrocardiography|Infusions, Intravenous|Emergency Care|Double-Blind Method|Biotin 31 Lingo2 26254004 J. Neurol. 2015 10.1007/s00415-015-7870-9 4 2 0 36 Humans|*Multiple System Atrophy|*Parkinson Disease|Allele Frequency|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Nerve Tissue Proteins|Alleles|Amyotrophic Lateral Sclerosis|Membrane Proteins|LINGO1 protein, human 31 Lingo2 25711307 Mol. Genet. Genomics 2015 10.1007/s00438-015-1009-7 6 0 0 36 Male|Female|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|Prospective Studies|Sweden|Adiposity|Body Mass Index|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Obesity|*Cohort Studies|Genetic Predisposition to Disease|Genotype|Phenotype|Genetic Loci 31 Lingo2 25680557 Gene 2015 10.1016/j.gene.2015.02.018 2 0 0 36 Humans|Animals|*Haploinsufficiency|Hedgehog Proteins|MicroRNAs|Base Sequence|Gene Expression Profiling|Multigene Family|Bioinformatic|Cell Differentiation|Genomics|Genome|*Craniofacial Abnormalities|MIRN873 microRNA, human|MIRN876 microRNA, human 31 LPHN2 26511811 Cancer Res Treat 2015 PMC4843720 10.4143/crt.2015.153 6 17 1 177 Humans|*Cisplatin|*Epigenesis, Genetic|*Gastrointestinal Cancer|CpG Islands|DNA Methylation|Promoter Regions, Genetic|Gene Silencing|Histones|Gene Expression Regulation, Neoplastic|Stomach Neoplasms|Epigenetic|Cell Line, Tumor|*Biomarkers|LPHN2 protein, human|Receptors, G-Protein-Coupled 29 LRIG3 26517670 Acta Neurol. Scand. 2015 PMC5057358 10.1111/ane.12515 4 8 1 135 *Charcot-Marie-Tooth Disease|Norway|Sequencing, Next-Generation|Genetic Testing|Pedigree|Mutation|*Genes, Regulator 50 LRIG3 26390694 Eur. J. Gynaecol. Oncol. 2015 1 0 0 135 Female|Humans|*Uterine Cervical Neoplasms|*Carcinoma, Squamous Cell|Immunohistochemistry|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|ErbB Receptors|Membrane Proteins|Apoptosis|LRIG3 protein, human 50 LRIG3 26198637 J. Biol. Chem. 2015 PMC4571947 10.1074/jbc.M115.644864 10 8 0 135 Animals|*Neural Crest|*Transcription Factor, Ets-1|HDAC1 protein, human|*Histone Deacetylase 1|Xenopus laevis|Xenopus Proteins|Neural Plate|*Signal Transduction|*Proto-Oncogenes|Ectoderm|Embryo, Nonmammalian|Bone Morphogenetic Proteins|*Neurogenesis|Gene Expression Regulation, Developmental|Transcription Factors|Cell Movement|Id3 protein, Xenopus|Inhibitor of Differentiation Proteins 50 LRIG3 25813475 Acta Oncol 2015 10.3109/0284186X.2015.1021427 12 0 2 135 *Carcinoma, Non-Small-Cell Lung|*Prognosis|*Lung Neoplasms|Carcinoma, Squamous Cell|Membrane Proteins|Biomarkers, Tumor|Genes, Tumor Suppressor|Membrane Glycoproteins|Downregulation 50 LRIG3 25708990 J. Neurol. Sci. 2015 10.1016/j.jns.2015.02.015 4 8 0 135 Humans|*Glioblastoma|*Apoptosis|EGFR protein, human|Epidermal Growth Factor Receptor|Cell Proliferation|Brain Neoplasms|Genes, erbB-1|Glioma|Cell Line, Tumor|Neoplasm Invasiveness|Signal Transduction|Xenograft Model Antitumor Assays|Cell Cycle|*Neoplastic Processes|LRIG3 protein, human|Membrane Proteins 50 LRRC26 26338706 J. Biol. Chem. 2015 PMC4646213 10.1074/jbc.M115.670885 18 2 1 54 Humans|*Cystic Fibrosis|pirfenidone|*Potassium Channel|*Dehydration|Mucociliary Clearance|*Pyridones|Respiratory Mucosa|Epithelial Cells|Bronchi|*Transforming Growth Factor|Ion Transport|Cells, Cultured|Signal Transduction|LRRC26 protein, human|Neoplasm Proteins 29 LRRC26 26009545 J. Gen. Physiol. 2015 PMC4442785 10.1085/jgp.201511356 7 26 1 54 Large-Conductance Calcium-Activated Potassium Channels|Ion Channel Gating|Large-Conductance Calcium-Activated Potassium Channel alpha Subunits|Membrane Potentials|Protein Subunits|Amino Acid Sequence|Potassium|Protein Domains|Calcium|Cytoplasm 29 LRWD1 25922909 Elife 2015 PMC4442312 10.7554/eLife.06496 21 40 2 85 *Heterochromatin|*Chromatin|*Histones|*Lysine|*Cell Nucleus|Histone Methyltransferases|Histone-Lysine N-Methyltransferase|Methylation|Mark, Histone|Origin Recognition Complex|Protein Processing, Post-Translational|DNA Replication|Protein Binding 22 LSG1 26272902 J. Exp. Bot. 2015 PMC4623693 10.1093/jxb/erv391 7 9 1 94 *Arabidopsis|*Auxin|*Active Transport, Cell Nucleus|Arabidopsis Proteins|Plant Growth Regulators|Gene Expression Regulation, Plant|Plant Roots|Ribosome|Membrane Transport Proteins|Homeostasis|Plant Leaves|Mutation|GTPase 26 LSG1 26219431 Proteins 2015 10.1002/prot.24869 1 1 0 94 Humans|carboxy-terminal domain kinase|*RNA Polymerase II|Protein Kinases|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Cyclin-Dependent Kinases|CCNK protein, human|Cyclin|Phosphorylation|*Cell Nucleus|CDK9 protein, human|Cyclin-Dependent Kinase 9|Amino Acid Sequence|Yeast, Fission|PCF11 protein, S cerevisiae|mRNA Cleavage and Polyadenylation Factors 26 Ly75 25658712 PLoS ONE 2015 PMC4319771 10.1371/journal.pone.0114919 25 1 4 198 Cattle|Animals|Female|Male|Pregnancy|Humans|*Genome-Wide Association Study|*Parity|Quantitative Trait Loci|Mastitis, Bovine|Genotype|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|*Genomics|*Mastitis|Lactation|SLURP1 protein, human|Antigens, Ly|Urokinase-Type Plasminogen Activator|PSCA protein, human|Antigens, Neoplasm|Neoplasm Proteins|GPI-Linked Proteins|C1QTNF3 protein, human 29 Ly75 25557950 Gastroenterology 2015 10.1053/j.gastro.2014.12.030 18 1 3 198 *Genome-Wide Association Study|*Crohn Disease|Genetic Predisposition to Disease|*Phenotypes|Colitis, Ulcerative|Polymorphism, Single Nucleotide|Case-Control Studies|Genotype|Inflammatory Bowel Disease 29 LYAR 26413750 Oncotarget 2015 PMC4741737 10.18632/oncotarget.5335 8 16 2 134 Humans|*Galectin 1|*Colorectal Cancer|*Cell Migration|HCT116 Cells|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Transcriptional Activation|Upregulation|Transcription Factor|Promoter Regions, Genetic|Epithelial-Mesenchymal Transition|Cell Proliferation|Signal Transduction|HT29 Cells|RNA Interference|*Colonic Neoplasms|Cell Line, Tumor|LYAR protein, human 32 LYAR 26203195 J. Biol. Chem. 2015 PMC4571879 10.1074/jbc.M115.637280 3 12 0 134 *Cyclin-Dependent Kinase Inhibitor p21|*S Phase|G1 Phase|Retinoblastoma Protein|Tumor Suppressor Protein p53|SAR1B protein, human|Cell Cycle|Transcription Factors|Up-Regulation|Transcription, Genetic|Cyclin-Dependent Kinase 4|Cyclin D1|Transcriptional Activation|GTP-Binding Proteins 32 LYAR 25735755 J. Cell. Biochem. 2015 PMC6456362 10.1002/jcb.25089 1 1 0 134 *Ligands|*Phagocytosis|*Cells, Cultured|Phagosomes|Retinal Photoreceptor Cell Outer Segment|*Retinal Pigments|Retinal Pigment Epithelium|Phagocytes|immunoglobulin B|*Immunoglobulins|Neurons 32 LYL1 26494788 Genes Dev. 2015 PMC4617977 10.1101/gad.267278.115 23 0 1 118 Humans|Mice|Animals|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|*Leukemia, Myeloid, Acute|RUNX1 Translocation Partner 1 Protein|Gene Expression Regulation, Leukemic|Translocation, Genetic|Oncogene Proteins, Fusion|Jumonji Domain-Containing Histone Demethylases|Cell Differentiation|Histone|Cell Line, Tumor|Oxidoreductases, N-Demethylating|Mice, Knockout|JMJD1C protein, human|JMJD1c protein, mouse 92 MAGEC1 26321295 Am. J. Surg. 2015 10.1016/j.amjsurg.2015.05.028 5 4 1 33 MAGEC2 protein, human|Antigens, Neoplasm|Neoplasm Proteins|Prognosis|Biomarkers, Tumor|Kaplan-Meier Estimate 67 MAGEC1 26161400 Biomed Res Int 2015 PMC4486606 10.1155/2015/432479 3 0 0 33 Melanoma, Cutaneous Malignant|*Melanoma|MAGEC2 protein, human|Skin Neoplasms|Antigens, Neoplasm|Neoplasm Proteins|Immunotherapy 67 MAGEC1 25793710 PLoS ONE 2015 PMC4368436 10.1371/journal.pone.0120734 3 0 0 33 Male|Humans|*Multiple Myeloma|*Flow Cytometry|Plasma Cells|Antigens, Neoplasm|Neoplasm Proteins|Bone Marrow|Antigens, CD19 67 MAP3K10 26587335 Oncoimmunology 2015 PMC4635878 10.1080/2162402X.2014.996475 6 0 1 161 Humans|*Leukemia, Myeloid, Acute|Daunorubicin|*Natural Killer Cells|Gene Expression Regulation, Leukemic|Apoptosis|HL-60 Cells|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Cytotoxicity, Immunologic 61 MAP3K10 25785089 Int J Clin Exp Med 2015 PMC4358544 3 0 0 161 Humans|Female|*Postmenopause|*Post-Menopausal Osteoporosis|Osteoporosis|Protein Interaction Maps|Gene Ontology|Gene Expression Profiling|*Microarray Analysis|Gene Expression|*B Cells|Databases, Genetic|Up-Regulation|Downregulation 61 MATN2 26649805 Mol. Endocrinol. 2015 PMC5414659 10.1210/me.2015-1208 10 0 1 125 Pregnancy|Female|Mice|Animals|*Proteomics|Islets of Langerhans|Insulin-Secreting Cells|*Cell Proliferation|Proteome|Insulin|*Cell Cycle|Up-Regulation|IGFBP5 protein, human|Insulin-Like Growth Factor Binding Protein 5|*Transcription Factors 55 MATN2 26436110 Mol Genet Genomic Med 2015 PMC4585452 10.1002/mgg3.155 8 11 0 125 Infant, Newborn|Humans|*Cleft Lip|*African Americans|Cleft Palate|Allele|Gene Frequency|Genetic Linkage|Genotype|Polymorphism, Single Nucleotide|*Palate|SLC25A32 protein, human|Membrane Transport Proteins|FZD6 protein, human|Frizzled Receptors|MATN2 protein, human|Matrilin Proteins 55 MATN2 26271809 Inflamm. Res. 2015 10.1007/s00011-015-0867-0 2 0 0 125 Mice|Animals|*Matrilin Proteins|Prospective Studies|Toll-Like Receptor 4|Mice, Knockout|Mice, Inbred C57BL|Cytokines|Signal Transduction|Extracellular Matrix 55 MATN2 26199591 Neural Regen Res 2015 PMC4498336 10.4103/1673-5374.158332 5 30 0 125 *Matrilin Proteins|Myoblasts|Extracellular Matrix|Cell Differentiation|Transforming Growth Factor beta|Bone Morphogenetic Protein|Signal Transduction Pathways|Extracellular Matrix Proteins|*Adaptor Proteins, Signal Transducing|Myogenesis|Cell Movement|Muscle, Skeletal|*Nerve Tissue|Cell Line|Regeneration 55 MATN2 26066748 Invest. Ophthalmol. Vis. Sci. 2015 10.1167/iovs.14-16008 5 0 1 125 Humans|*Trabecular Meshwork|*DNA Methylation|Glucocorticoid|Dexamethasone|Cell Line|Eye Proteins|Cells, Cultured|Blotting, Western|Gene Expression 55 MCTS1 26699426 J Control Release 2015 10.1016/j.jconrel.2015.12.020 12 0 2 209 Mice|Animals|*Chitosan|*RNA, Small Interfering|*Nanoparticles|Drug Delivery Systems|Polyethylene Glycols|*Ligands|Gene Silencing|Cell Line, Tumor|arginyl-glycyl-aspartic acid|Oligopeptides|Cell Survival|*RNA, Double-Stranded|Hydrophobic and Hydrophilic Interactions 66 MCTS1 26563366 Tumour Biol. 2015 10.1007/s13277-015-4385-z 4 2 0 209 Humans|Female|*Uterine Cervical Neoplasms|*Cervix Uteri|*Lactate|STAT3 protein, human|*STAT3 Transcription Factor|Human Papilloma Virus|Squamous Cell Carcinomas|Adenocarcinomas|HeLa Cells|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Tumor Microenvironment|FOXM1 protein, human|Forkhead Box Protein M1 66 METRN 26121675 PLoS ONE 2015 PMC4487999 10.1371/journal.pone.0131013 3 0 0 47 Female|Pregnancy|Humans|*Pre-Eclampsia|Case-Control Studies|Longitudinal Studies|Placenta Growth Factor|Cohort Study|Biomarkers|METRN protein, human|Nerve Tissue Proteins|Intercellular Signaling Peptides and Proteins 22 MICAL2 26689989 Oncotarget 2015 PMC4811499 10.18632/oncotarget.6577 16 8 1 153 Humans|*Epithelial-Mesenchymal Transition|Cell Movement|*Oncogenes|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|RNA Interference|Microfilament Proteins|Immunohistochemistry|Actin Cytoskeleton 22 MICAL2 26635870 Front Genet 2015 PMC4653304 10.3389/fgene.2015.00334 11 2 1 153 Humans|Male|Female|Child|Adolescent|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|Mycobacterium leprae|Leprosy|Leprosy, Lepromatous|Skin|Biopsy|mRNA|FOXQ1 protein, human|Forkhead Transcription Factors|GPNMB protein, human|Membrane Glycoproteins|FAM26F protein, human 22 MICAL2 26461418 Free Radic. Biol. Med. 2015 10.1016/j.freeradbiomed.2014.10.848 1 0 0 153 Animals|methionine sulfoxide|*Selenium|*Methionine|Selenoproteins|Methionine Sulfoxide Reductases|Selenocysteine|Redox|Racemethionine|Catalysis|Actin|Mammals 22 MICAL2 25601765 Sci Rep 2015 PMC4298747 10.1038/srep07890 22 35 3 153 Mice|Animals|Male|*Capillary Permeability|Endothelial Cells|Vascular Endothelial Growth Factor A|Semaphorin-3A|FLT1 protein, human|VEGFR-1|Neuropilin-1|*Brain|neuropilin-2, human|Neuropilin-2|Brain Ischemia|Cultured Cells|Disease Models, Animal|Middle Cerebral Artery Occlusion|Signal Transduction|Stroke|Cell Line 22 MIDN 26333845 Clin Transplant 2015 10.1111/ctr.12625 0 0 0 245 Humans|*Quality of Life|*Prospective Studies|*Nephrectomy|*Tissue and Organ Harvesting|Living Donors|Kidney Transplantation|*Kidney|Laparoscopy|*Surgical Wound 23 MIDN 25574603 Int J Mol Sci 2015 PMC4307305 10.3390/ijms16011312 27 3 6 245 Female|*Whole Exome Sequencing|*Autistic Disorder|Exome|Genetic Predisposition to Disease|Sequencing, Next-Generation|Sequence Analysis, DNA|Polymorphism, Single Nucleotide|Autism Spectrum Disorders|Software 23 MIEN1 26484354 Biomed Res Int 2015 PMC4592899 10.1155/2015/834805 6 3 1 102 Humans|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn's Disease|*Genotype|Colon|Intestinal Mucosa|Genetic Predisposition to Disease|Gene Frequency|Ileum|Polymorphism, Single Nucleotide|Inflammation|Biopsy|Proteins|GSDMA protein, human|Neoplasm Proteins|MIEN1 protein, human|Intracellular Signaling Peptides and Proteins|GSDMB protein, human 33 MIEN1 26272794 Mol. Cancer 2015 PMC4536591 10.1186/s12943-015-0428-8 16 32 1 102 *Annexin A2|Cell Motility|Cell Line, Tumor|Neoplasm Proteins|*Plasma Membrane|Phosphorylation|Intracellular Signaling Peptides and Proteins 33 MIPEP 25807486 Nature 2015 10.1038/nature14346 63 0 10 43 *MicroRNAs|Medicago truncatula|RNA, Plant|Gene Expression Regulation, Plant|Arabidopsis thaliana|Plant Proteins|Plant Roots|*Peptides|Open Reading Frame|Messenger RNA 29 MIR135B 26523217 Iran J Basic Med Sci 2015 PMC4620183 5 3 0 0 SD-208|*Down-Regulation|*Pteridines|*Adenocarcinoma|*Colonic Neoplasms|Colorectal Cancer|miRNAs|*Protein Kinase Inhibitors|*Transforming Growth Factor|Transforming Growth Factor beta|Signal Transduction|Cell Line, Tumor|Cell Proliferation|Xenograft Model Antitumor Assays|Colon 26 MIR135B 26429530 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2015 1 0 0 0 *Carcinoma, Hepatocellular|*Liver Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Movement|*Neoplastic Processes|Cell Line, Tumor|Cell Proliferation|Down-Regulation|Signal Transduction 26 MIR135B 26355456 PLoS ONE 2015 PMC4565637 10.1371/journal.pone.0137067 0 0 1 0 Female|*Semen|*Stains|*Body Fluid|Forensic Genetics|RNA, Micro|Real-Time PCR, Quantitative|Saliva|*Bodily Secretions|Biomarkers|Menstruation|*Staining and Labeling 26 MIR135B 26134897 Int. 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Rep. 2015 10.3892/or.2014.3694 5 7 0 0 Humans|*Glycolysis|Phosphatidylinositol 3-Kinases|PTEN protein, human|*PTEN Phosphohydrolase|*Colorectal Cancers|MicroRNAs|Cell Proliferation|Adenomatous Polyposis Coli|Gene Expression Regulation, Neoplastic|Proto-Oncogene Proteins c-akt|Downregulation|3' Untranslated Regions|Cell Line, Tumor|Signal Transduction|Apoptosis|*Peptide Hydrolases|USP13 protein, human|Endopeptidases 26 MLLT11 26341630 BMC Mol. Biol. 2015 PMC4560861 10.1186/s12867-015-0043-7 1 14 1 143 RE1-silencing transcription factor|*Repressor Proteins|*Transcription Factors|Promoter Regions, Genetic|Neurogenesis|Oncogenes|Neurons|Transcription, Genetic|Chromosomes 40 MLLT11 26079538 Oncotarget 2015 PMC4653036 10.18632/oncotarget.4136 14 18 4 143 Humans|CD44 protein, human|*Hyaluronan Receptors|Neoplasm Invasiveness|Neoplasm Proteins|*Transcription Factors|Cell Line, Tumor|Cell Movement|Epithelial-Mesenchymal Transition|Proto-Oncogene Proteins|Wnt Signaling Pathway|TCF7 protein, human|T Cell Transcription Factor 1 40 MORC1 26275923 Behav. Brain Res. 2015 10.1016/j.bbr.2015.08.005 6 0 1 59 Humans|Female|Mice|Animals|*Depression|Depressive Disorder, Major|Genome-Wide Association Study|*Mice, Inbred C57BL|BDNF protein, human|BDNF|Anxiety|Hippocampus|*Phenotype|Helplessness, Learned|Stress, Life|Behavior, Animal|Disease Models, Animal|Swimming|Morc1 protein, mouse|Nuclear Proteins 26 MORC1 25822715 Mol. Plant Microbe Interact. 2015 10.1094/MPMI-12-14-0401-R 4 6 1 59 *ATPase|*Plant Immunity|Phytophthora infestans|Tobacco|Potato|Tomato|Plant Diseases|Plant Proteins|Gene Expression Regulation, Plant|Gene Silencing|Arabidopsis|Cell Death 26 MPZL2 26677976 Cancer Res. 2015 10.1158/0008-5472.CAN-15-0884 13 1 1 144 Humans|*Glioblastoma|Neoplasm Recurrence, Local|*Signal Transduction|Brain Neoplasms|Neoplastic Stem Cells|NF-kappa B|Cell Line, Tumor 22 MPZL2 26458419 Mol Med Rep 2015 10.3892/mmr.2015.4376 0 3 0 144 Rats|Animals|*Subtilisin|*Rheumatoid Arthritis|KEX2 protein, S cerevisiae|*Proprotein Convertases|Synoviocytes|pros protein, Drosophila|*Nuclear Proteins|Synovial Membrane|*Transcription Factors|prosubtilisin|*Synovitis|Cell Proliferation|*Nerve Tissue Proteins|*Drosophila Proteins|Cell Movement|RNA, Small Interfering|*Peptide Fragments|*Saccharomyces cerevisiae Proteins 22 MPZL2 26428916 Pharm Biol 2015 10.3109/13880209.2015.1071414 6 0 0 144 3,4,5,4'-tetramethoxystilbene|*Endothelial Cells|*Stilbenes|Resveratrol|Apoptosis|Cell Line, Tumor|Effects, Antiangiogenesis|*Gene Expression Profiling|DMU-212|*Microarray Analysis|*Cell Death 22 MPZL2 25983633 Genet. 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Acta 2015 10.1016/j.bbamcr.2015.10.009 32 0 2 133 Humans|*Mitochondrial Membranes|*Mitochondria|Mitochondrial Proteins|Membrane Proteins|Multiprotein Complexes|Protein Binding|*Morphogenesis 21 MXRA5 26643872 Oncotarget 2015 PMC4767443 10.18632/oncotarget.6464 35 10 3 21 Humans|Adult|*Liposarcoma|Gene Amplification|Soft Tissue Neoplasms|Soft Tissue Sarcoma|*Genomics|Oligonucleotide Array Sequence Analysis|Oncogene|Mutations|Polymorphism, Single Nucleotide|In Situ Hybridization, Fluorescence|Sequencing, Whole Exome|HMGA2 Protein|Biomarkers, Tumor|Genes, Neurofibromatosis 1|CHEK1 protein, human|Checkpoint Kinase 1 23 MXRA5 26505536 Mol. Phylogenet. Evol. 2015 10.1016/j.ympev.2015.10.005 2 0 0 21 Animals|Phylogeny|Australia|*Geckos|*Hybridization, Genetic|*Mitochondria|Genetic Speciation|DNA, Mitochondrial|Evolution, Molecular|Geography|Models, Genetic|Sequence Analysis, DNA|*Nucleic Acid Hybridization|Likelihood Functions|Cell Nucleus|New Guinea 23 MXRA5 26406953 Cancer Biomark 2015 10.3233/CBM-150504 7 0 1 21 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Prognosis|Kaplan-Meier Estimate|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Real-Time Polymerase Chain Reaction 23 MXRA5 25864925 Am. J. 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Anat. 2015 PMC4560570 10.1111/joa.12353 12 6 1 40 Mice|Animals|*Myogenesis|*Chickens|myogenic factor 6|Myogenic Regulatory Factors|*Muscle, Skeletal|*Mesoderm, Paraxial|Myogenic Regulatory Factor 5|MyoD Protein|*Antigens, Differentiation|Muscle Proteins|Gene Expression Regulation, Developmental|Zebrafish|DNA-Binding Proteins|Myosin Heavy Chain|Muscle Cells|Cell Differentiation 24 MYH15 25621163 Pulm Circ 2015 PMC4278609 10.1086/677364 4 0 0 40 Humans|Cattle|Animals|Male|Horses|nonmuscle myosin type IIB heavy chain|*Myosin Heavy Chains|*Arterial Pressure|Hypertension, Pulmonary|Altitude Sickness|*Nonmuscle Myosin Type IIB|Altitude|Pulmonary Artery|Hypoxia|Blood Pressure|Gene Frequency|Lung|Polymorphism, Genetic 24 MYO18B 26558807 J. Pediatr. Hematol. Oncol. 2015 PMC4681625 10.1097/MPH.0000000000000463 2 0 0 35 Young Adult|Humans|Child|*Carcinoma, Neuroendocrine|DNA Mutational Analysis|*Genomics|*Cell Differentiation|Sequencing, Whole Exome|Mutation|Genes, ras 42 MYO5C 26715629 Mol. 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Neurosci. 2015 PMC6605387 10.1523/JNEUROSCI.2247-15.2015 6 1 0 77 Mice|Animals|*Olfactory Receptor Neurons|*CYP26B1|Olfactory Epithelium|*Smell|Olfactory Bulbs|Receptors, Odorant|Cell Differentiation|Mice, Transgenic|Neurogenesis|Axons|Gene Expression Regulation, Developmental|adenylate cyclase 3|Adenylyl Cyclases|Retinoic Acid|Animals, Newborn|Cyp26b1 protein, mouse 71 NCAM2 25875008 PLoS ONE 2015 PMC4395419 10.1371/journal.pone.0122337 1 16 0 77 Mice|Animals|ERBB2 protein, human|*Receptor, ErbB-2|Axons|Neurons|Cell Differentiation|Neural Cell Adhesion Molecules|NCAM2 protein, human|Neural Cell Adhesion Molecule L1|Signal Transduction|Spinal Cord|Cell Adhesion Molecules|Oligodendrocytes|Cell Adhesion|Smell|Gene Expression Regulation, Developmental|Cell Proliferation|Ncam2 protein, mouse 71 NCAM2 25710561 PLoS ONE 2015 PMC4339844 10.1371/journal.pone.0117818 9 45 2 77 *Trastuzumab|*mRNA|Receptor, ErbB-2|Drug Resistance, Neoplasm|Antibodies, Monoclonal, Humanized|Antineoplastic Agents|Antibodies, Monoclonal|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Proliferation|RNA, Small Interfering|Up-Regulation 71 NCAM2 25632147 J. 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Reprod. 2015 10.1095/biolreprod.115.131334 5 12 0 101 Pregnancy|Female|Animals|Mice|Humans|olfactomedin|C-terminal binding protein|Cell Line, Tumor|*Endometrium|Implantation, Embryo|Extracellular Matrix Proteins|Glycoproteins|DNA-Binding Proteins|Alcohol Oxidoreductases|*Cells, Epithelial|Downregulation|MIRN212 microRNA, human|MicroRNAs|Trophoblasts|Fallopian Tube|Chorionic Gonadotropin|Pregnancy, Tubal|Blastocyst 31 olfm1 26121352 PLoS ONE 2015 PMC4488277 10.1371/journal.pone.0130888 9 0 1 101 Humans|olfactomedin|trabecular meshwork-induced glucocorticoid response protein|*Glycoproteins|*Extracellular Matrix Proteins|Eye Proteins|Cytoskeletal Proteins|Protein Structure, Tertiary|Glaucoma|Amino Acid Sequence|Protein Domains|Ligands|Models, Molecular|Mutation 31 olfm1 26107991 Endocrinology 2015 PMC4541623 10.1210/en.2015-1389 5 2 1 101 Female|Male|Pregnancy|Humans|Animals|Horses|Mice|*Smell|olfactomedin|Glycoprotein|Extracellular Matrix Proteins|Accessory Olfactory Bulb|Vomeronasal Organ|Olfactory Pathways|Gn-RH|Olfactory Epithelium|Hypothalamus|Neurons|Odorants|Sexual Behavior, Animal|Ovulation|Implantation, Embryo|Proto-Oncogene Proteins c-fos|Chorionic Gonadotropin|Brain 31 olfm1 25999259 Fertil. Steril. 2015 10.1016/j.fertnstert.2015.04.030 1 1 0 101 Pregnancy|Humans|Female|*Fallopian Tubes|olfactomedin|*Down-Regulation|Glycoproteins|Extracellular Matrix Proteins|*Chorionic Gonadotropin|*Cells, Epithelial|Pregnancy, Tubal|*Mitogen-Activated Protein Kinases|Embryo Implantation|Coculture Techniques|*Central Nervous System Stimulants 31 olfm1 25903135 J. Biol. Chem. 2015 PMC4463452 10.1074/jbc.M115.653485 6 8 0 101 olfactomedin|trabecular meshwork-induced glucocorticoid response protein|Glycoprotein|Extracellular Matrix Proteins|Eye Proteins|Cytoskeletal Proteins|Amino Acid Sequence|Binding Sites|Crystallography, Xray|*Protein Domains|Signal Transduction|Disulfides 31 olfm1 25773404 Diabetologia 2015 PMC4415993 10.1007/s00125-015-3552-5 1 5 1 101 Mice|Animals|Diabetes Mellitus, Type 2|Pancreatic beta Cells|Interleukin-1beta|NF-kappa B|Tumor Necrosis Factor-alpha|Signal Transduction|Apoptosis|*B-Lymphocytes|Interferon-gamma|Cell Survival|Cell Line|*Survey 31 olfm1 25595337 Psychiatry Res 2015 10.1016/j.psychres.2014.12.028 7 0 2 101 Male|Humans|*Tourette Syndrome|*Attention Deficit Disorder with Hyperactivity|*Obsessive Compulsive Disorder|Tic Disorders|Tics|Comorbidity|*Translocation, Genetic|Phenotype|DNA Copy Number Variations 31 OLFML3 26437222 Oncotarget 2015 PMC4741452 10.18632/oncotarget.5924 13 12 1 48 Humans|*Cetuximab|*Epithelial-Mesenchymal Transition|*Cancer-Associated Fibroblasts|*Head and Neck Cancer|Squamous Cell Carcinoma of Head and Neck|Squamous Cell Carcinoma|ErbB Receptors|Cell Line, Tumor|Antibodies, Monoclonal, Humanized 21 OSCP1 26411401 FEBS J. 2015 10.1111/febs.13528 5 3 1 406 Animals|*Drosophila melanogaster|*Reactive Oxygen Species|Imaginal Discs|*Cell Differentiation|Drosophila Proteins|Drosophila|*Apoptosis|Photoreceptor Cells, Invertebrate|Signal Transduction|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Pupae|Eye|ErbB Receptors|Cell Death|Phenotype|Downregulation|*Organogenesis 62 OSCP1 26175940 Am J Cancer Res 2015 PMC4497438 1 4 0 406 Animals|*Drosophila melanogaster|*Apoptosis|Imaginal Discs|Drosophila|Cell Differentiation|*Tumor Suppressor Proteins|Cell Proliferation|Membrane Transport Proteins|S Phase|Eye|OSCP1 protein, Drosophila|Drosophila Proteins 62 OTOG 26636018 Springerplus 2015 PMC4659790 10.1186/s40064-015-1537-y 3 1 1 16 Humans|Mice|Animals|*Ethylnitrosourea|Nonsyndromic Deafness|*Deafness|*Hearing Loss|Hearing Loss, Sensorineural|Homozygote|Mutation|Phenotype|Mutagenesis|Alleles|Vestibule, Labyrinth|*Disease Models, Animal|Membrane Glycoproteins|Intron 35 OTOG 25758224 Development 2015 PMC4360185 10.1242/dev.116632 13 0 2 16 Animals|Humans|*Zebrafish|*Otolithic Membrane|Zebrafish Proteins|Deafness, Autosomal Recessive 21|Hearing Loss, Sensorineural|Hair Cells, Auditory|Cilia|Deafness, Autosomal Dominant 12|Extracellular Matrix Proteins|Tectorial Membrane|*Organogenesis|In Situ Hybridization|Amino Acid Sequence|Vestibule, Labyrinth|Microscopy, Video|Phenotype 35 OTOP1 26418998 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2015 10.3760/cma.j.issn.1003-9406.2015.05.023 0 0 0 24 Male|Humans|*Polymorphism, Single Nucleotide|*Diabetes Mellitus, Type 2|*Asian Continental Ancestry Group|*Gout|*Ethnic Groups|Genetic Predisposition to Disease|Gene Frequency|Genetic Association Studies|Alleles|Genotypes 23 oxsr1 26303911 BMC Genomics 2015 PMC4548451 10.1186/s12864-015-1732-9 7 0 1 594 Mice|Animals|*MicroRNAs|*Hypersensitivity|Gene Regulatory Networks|Asthma|Gene Expression Regulation|Gene Expression Profiling|Quantitative Trait Loci|Oligonucleotide Array Sequence Analysis|Lung|*Genetics, Population|Antigens, Dermatophagoides|Phenotypes|Inflammation|Disease Models, Animal 38 oxsr1 26260799 Cardiovasc. Res. 2015 10.1093/cvr/cvv210 9 0 2 594 Humans|*Myocytes, Cardiac|*Heart Failure|AKT1 protein, human|*Protein Kinase B 38 PACRG 25715396 Development 2015 PMC4352978 10.1242/dev.119834 13 9 1 62 Male|Mice|Animals|*Sperm Flagellum|Spermatids|*Meiosis|Spermiogenesis|Nuclear Proteins|Cell Cycle Proteins|Sperm|Phosphoproteins|Testis|Spermatocytes|*Cytoskeleton|*Gene Expression Regulation|Flagella|parkin protein|*Ubiquitin-Protein Ligases|Pacrg protein, mouse|Proteins|Meig1 protein, mouse 68 pacs2 26108729 Nat Commun 2015 PMC4481878 10.1038/ncomms8518 16 22 3 228 Mice|Animals|ADAM17 protein, human|*ADAM-17|*Signal Transduction|*Genes, erbB|ErbB Receptors|ADAM Proteins|Transforming Growth Factor alpha|Cell Movement|Phosphorylation|*Protein Sorting|Cell Line, Tumor|Adam17 protein, mouse|Pacs2 protein, mouse|Vesicular Transport Proteins 38 PAGE4 26242913 J. Biol. Chem. 2015 PMC4599013 10.1074/jbc.M115.658583 26 2 3 57 Humans|Male|*Phosphorylation|*Testis|Prostate|PSCA protein, human|Antigens, Neoplasm|Prostate Cancer|Protein Conformation|Intrinsically Disordered Proteins|Cell Line, Tumor|Transcriptional Activation|Apoptosis|Neoplasm Proteins|GPI-Linked Proteins|PAGE4 protein, human 31 PAGE4 25811964 Anticancer Drugs 2015 10.1097/CAD.0000000000000232 2 0 1 57 Humans|coumarin|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|2H-chromen-2-one|*Coumarins|*Signal Transduction|*Caspase-Dependent Apoptosis|benzimidazole|*Benzimidazoles|Cell Proliferation|Drug Screening Assays, Antitumor|Antineoplastic Agents|Cell Line, Tumor|Structure-Activity Relationship|Molecular Structure|Upregulation 31 PAGE4 25733303 Urology 2015 PMC4695987 10.1016/j.urology.2014.12.004 4 1 1 57 Humans|Male|*Testis|*Nanowires|*Prostate Cancer|*Prostate|Antigens, Neoplasm|Cancer Biomarkers|Immunotherapy 31 PARM1 26702338 Genes Genomics 2015 PMC4684836 10.1007/s13258-015-0332-z 1 1 0 49 Humans|Female|Male|*Alleles|Genome-Wide Association Study|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Frequencies, Allele|Genotype|African Americans|Genetic Markers|*Sex Difference 20 PARM1 26447881 PLoS ONE 2015 PMC4598026 10.1371/journal.pone.0139520 1 32 1 49 IGF1 protein, human|*Insulin-Like Growth Factor I|*Tumor Necrosis Factor-alpha|*Kinetics|*Cell Differentiation|*Muscle Development|Myoblasts, Skeletal|Muscular Atrophy|*Gene Expression|Cell Line|Apoptosis|Muscle, Skeletal|Cells, Cultured 20 PARP12 26005050 J. Autoimmun. 2015 PMC4497927 10.1016/j.jaut.2015.05.003 25 6 2 93 Humans|*DNA Methylation|*CD4-Positive T-Lymphocytes|*Lupus Erythematosus, Systemic|*Lupus Erythematosus, Discoid|Epigenetic|Lupus Nephritis|Type I Interferon|Genome-Wide Association Study|*Kidney|Regulatory Genes|Signal Transduction|TNK2 protein, human|Protein-Tyrosine Kinases 20 PARP12 25635049 J. Biol. Chem. 2015 PMC4367243 10.1074/jbc.M114.630160 9 0 1 93 Humans|Animals|*Poly ADP Ribose Polymerase|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|ADP-Ribosyltransferase|Active Site|Diphtheria Toxin|Crystallography, Xray|Models, Molecular|*Antiviral Agents|Mammals|Zinc Fingers 20 parpbp 26513298 Oncotarget 2015 PMC4747407 10.18632/oncotarget.5846 9 21 1 100 *Poly(ADP-ribose) Polymerase Inhibitors|*Wnt Signaling Pathway|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|olaparib|Phthalazines|Tankyrases|Xenograft Model Antitumor Assays|Cell Line, Tumor|Piperazines|Cell Proliferation|Axin Protein|*Repair, Deficient DNA|beta Catenin|niraparib|Piperidines|Indazoles|Apoptosis 25 parpbp 26348451 Prev Med 2015 10.1016/j.ypmed.2015.08.018 1 0 1 100 Female|Humans|Aged|*Vaginal Smears|*Prevalence|Papillomaviridae|Papanicolaou Test|Cervical Intraepithelial Neoplasia|Papillomavirus Infections|Uterine Cervical Neoplasms|*Screening|Early Detection of Cancer|DNA, Viral|*Cohort Studies|*Hospital 25 parpbp 26334372 Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2015 PMC4662871 10.1016/j.cbpc.2015.08.006 12 1 0 100 Animals|*Down-Regulation|*Xiphophorus|*Skin|Transcription, Genetic|Light|Fluorescence|*Disease Progression 25 pax6a 26470995 Birth Defects Res. Part A Clin. Mol. Teratol. 2015 PMC4697881 10.1002/bdra.23460 8 43 0 0 Animals|*Zebrafish|*Retinoic Acid|*Ethanol|*Hedgehog Proteins|Zebrafish Proteins|Embryo, Nonmammalian|*Signal Transduction|Teratogens|Gene Expression Regulation, Developmental|Homeodomain Proteins|Eye 32 pax6a 26283463 Dev. Dyn. 2015 PMC4619121 10.1002/dvdy.24322 8 5 0 0 Animals|*Zebrafish|*Retina|Zebrafish Proteins|Embryo, Nonmammalian|Animals, Genetically Modified|Retinal Rod Photoreceptor Cells|Neuroglia|Cell Differentiation|Eye Proteins|Basic Helix-Loop-Helix Transcription Factors|Cell Proliferation|Nerve Regeneration|cloche protein, zebrafish 32 pax6a 29124181 Biochem Biophys Rep 2015 PMC5668850 10.1016/j.bbrep.2015.08.003 3 4 1 0 32 pax6a 26034575 Evodevo 2015 PMC4450993 10.1186/s13227-015-0010-x 5 1 0 0 Animals|*Spiders|Homeodomain Proteins|*Retina|Transcription Factors|Arthropods|Gene Expression Regulation, Developmental 32 PCDH11Y 26144214 J. Proteome Res. 2015 10.1021/acs.jproteome.5b00512 9 0 0 45 Humans|Male|*Genes, Y-Linked|Proteomics|Spermatogenesis|Azoospermia|Testis|Chromosomes, Human, Y|DEAD-box RNA Helicases|Transcription, Genetic|Proteins|Minor Histocompatibility Antigens|Cell Differentiation|DDX3Y protein, human 24 PCNP 26696758 Biodivers Data J 2015 PMC4678797 10.3897/BDJ.3.e5260 1 0 1 156 Animals|*Caves|*Arachnids|*Limestone|Brazil|Ecosystem|*Records|Park, National|Tongue Diseases 59 PCNP 28970375 Pharmacy (Basel) 2015 PMC5419351 10.3390/pharmacy4010002 3 0 0 156 Child|Humans|*Health Information Technology|Medication Therapy Management|Pharmaceutical Services|E-Prescriptions|Pharmacies|Drug Compounding 59 PDE3B signalling 25702569 J. Neuroendocrinol. 2015 10.1111/jne.12266 7 3 0 0 Male|Animals|Mice|*Leptin|*Hypothalamus|*Obesity|*Phosphodiesterase, CAMP|*Signal Transduction|Body Weight|Phosphodiesterase 3B|Diet, High-Fat|Mice, Obese|Arcuate Nucleus|*Mice, Inbred Strains|Phosphorylation|STAT3 Transcription Factor|Weight Loss|Hyperphagia|Diet, Fat-Restricted 21 pdia2 26708639 Am. J. Cardiol. 2015 10.1016/j.amjcard.2015.10.058 7 0 0 61 Humans|Male|Female|Bicuspid Aortic Valve|*Heart Valve Diseases|*Aortic Valve|Frequencies, Allele|Genotype|Polymorphism, Genetic|Genetic Variation|Phenotype|Sequencing, Next-Generation|Case-Control Studies|Aorta|Base Sequence|TGFBR2 protein, human|TGFBR2 23 pdia2 25631539 Thromb. Haemost. 2015 10.1160/TH14-09-0776 1 1 0 61 Animals|Mice|Humans|*Thromboplastin|*Protein Disulfide-Isomerases|*Muscle, Smooth, Vascular|Endothelial Cells|Mice, Nude|*Cell Movement|Smooth Muscle Cells|Cell Migration Assays|*Cytoplasm|Microvessel|Cell-Derived Microparticles|Signal Transduction|Cells, Cultured|Plaques, Atherosclerotic|Coronary Artery Disease 23 PDLIM1 26701804 Cancer Res. 2015 10.1158/0008-5472.CAN-15-1962 28 1 1 164 Humans|*Epithelial-Mesenchymal Transition|CDH1 protein, human|*E Cadherin|*Colorectal Cancer|*Antigens, CD|*Colonic Neoplasms|beta Catenin|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|*Cell Membrane|Liver Neoplasms|Transcription Factors|Signal Transduction|Cell Line, Tumor|Downregulation 43 PDLIM1 26679095 Sci Rep 2015 PMC4683373 10.1038/srep18327 15 50 1 164 *Signal Transduction|*Cytoplasm|PDLIM2 protein, human|LIM Domain Proteins|I-kappa B Proteins|NF-kappa B|Transcription Factor RelA|NF-KappaB Inhibitor alpha|Cell Nucleus|Microfilament Proteins|DNA-Binding Proteins|Protein Binding|Phosphorylation|Ubiquitin Ligase E3 43 PDLIM1 26119933 Oncogene 2015 PMC4800290 10.1038/onc.2015.199 5 45 1 164 Humans|*Receptor, Nerve Growth Factor|*CD271|NGFR protein, human|*Receptors, Nerve Growth Factor|*Glioma|*Nerve Tissue Proteins|Glioblastoma|Signal Transduction|shRNA|Cell Line, Tumor|Nerve Growth Factor|Phosphorylation|Tumor Initiating Cells|Protein Binding 43 PDZD2 26708285 Atherosclerosis 2015 10.1016/j.atherosclerosis.2015.11.019 17 0 1 125 Humans|*Genome-Wide Association Study|Coronary Artery Disease, Autosomal Dominant, 1|*Coronary Artery Disease|*Arabs|Saudi Arabia|*Myocardial Infarction|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|Risk Factors 57 PDZD2 26616883 J. Neuroimmunol. 2015 10.1016/j.jneuroim.2015.11.002 0 0 0 125 Humans|*Neuromyelitis Optica|*Exome|Aquaporin 4|Autoantibodies|*Regulatory Region|Finland 57 PDZD2 26459785 Curr Gene Ther 2015 10.2174/1566523215666151013140859 0 3 0 125 Rats|Animals|*Hyperplasia|*RNA, Small Interfering|*Poloxamer|Telomere Shortening|Telomere|*Neointimas|Muscle, Smooth, Vascular|Cell Proliferation|Phosphorylation|Cell Movement|Proto-Oncogene Proteins c-akt|Signal Transduction|Cells, Cultured|Lentivirus 57 PDZD2 26330360 Sci Rep 2015 PMC4557136 10.1038/srep13750 23 3 4 125 *Stomach Neoplasms|*Transcriptome|Neoplasm Recurrence, Local|*Peritoneum|Peritoneal Neoplasms|*Whole Exome Sequencing|Gene Expression Regulation, Neoplastic|Transcriptome Analysis|Oligonucleotide Array Sequence Analysis|Mutation|*Carcinoma|China 57 PDZD2 25930081 Am. J. Physiol. Gastrointest. Liver Physiol. 2015 PMC4491506 10.1152/ajpgi.00080.2015 11 0 0 125 Humans|*Irritable Bowel Syndrome|*Bile|*Colon|*Bile Acids and Salts|Diarrhea|*Intestinal Mucosa|Gastrointestinal Transit|Feces|*Gene Expression|Rectum|Gastrointestinal Motility|*Biological Transport|*Genotype|Tight Junctions|Case-Control Studies|GPBAR1 protein, human|Receptors, G-Protein-Coupled 57 PDZD2 25663627 J Gene Med 2015 10.1002/jgm.2822 3 0 1 125 *Transcriptome|*Polymer|*Transfection|Gene Delivery Systems|Polyethyleneimine|Genetic Vectors|Genes, Reporter|DNA|Green Fluorescent Proteins|Lipids 57 PDZD7 26416264 Am. J. Med. Genet. A 2015 PMC4741280 10.1002/ajmg.a.37274 0 3 1 36 Iran|*Hearing Loss|Homozygote|Genes, Recessive|Mutations|Pedigree|Deafness|Connexins|Heterogeneities, Genetic|Genetic Linkage|Genomics|Massively Parallel Sequencing|Carrier Proteins|Phenotype 30 PDZRN3 26537429 Sci Rep 2015 PMC4633681 10.1038/srep16264 5 2 1 80 Animals|*Quantitative Trait Loci|*Genome-Wide Association Study|*Circadian Rhythm|Period Circadian Proteins|SNPs|*Hypothalamus|*Genes, Regulator|Phenotype|*Adaptation, Psychological 26 PDZRN3 25651471 Am. J. Surg. Pathol. 2015 PMC4431898 10.1097/PAS.0000000000000389 14 3 0 80 Female|In Situ Hybridization, Fluorescence|*PEComa|Gene Fusion|Rearrangements, Gene|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Biomarkers, Tumor|Cell Cycle Proteins|Genes, cdc 26 PGDF 26584592 Biomed Mater 2015 10.1088/1748-6041/10/6/065013 2 0 0 0 *Glycerol|*Polymer|*Cell Differentiation|Tissue Engineering|Tissue Scaffolds|*Neurogenesis|Polyesters|*Motor Neuron|Gelatin|peptide B|Nerve Tissue|Materials Testing|Cells, Cultured|Viability, Cell|Cell Adhesion|fumaric acid|*Fumarates|Peptides 49 PGDF 26567091 Int J Comput Assist Radiol Surg 2015 10.1007/s11548-015-1321-z 1 0 0 0 Cross-Sectional Studies|Aortic Aneurysm, Abdominal|Algorithms|Imaging, Three-Dimensional|Aorta, Abdominal|Tomography, X-Ray Computed 49 PGDF 26262503 Transplantation 2015 10.1097/TP.0000000000000837 4 2 0 0 *Kidney Transplantation|*Platelet Derived Growth Factor B|*Sunitinib|*Vascular Endothelial Growth Factor A|*Transplantation, Homologous|Graft Rejection|Receptors, Platelet Derived Growth Factor|Transplantation, Isogeneic|Cyclosporine|*Angiogenesis Inhibitors|Becaplermin|Allografts 49 PHLDB1 26610392 Sci Rep 2015 PMC4661592 10.1038/srep17367 9 11 1 51 Humans|Genome-Wide Association Study|*Glioma|SNPs|Brain Neoplasms|Genetic Predisposition to Disease|Linkage Disequilibrium|Allele|Asian Continental Ancestry Group|*Chromosomes, Human|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|Genotype|Case-Control Studies|Promoter Regions, Genetic|DDX6 protein, human|Proto-Oncogene Proteins|DEAD-box RNA Helicases|PHLDB1 protein, human 41 PHLDB1 26243184 Mol. Neurobiol. 2015 10.1007/s12035-015-9346-4 3 0 0 51 Adult|Humans|*Genome-Wide Association Study|*Glioma|Brain Neoplasms|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Case-Control Studies|Alleles|Odds Ratio|Mutations|China 41 PHLDB1 26156397 Med. Sci. Monit. 2015 PMC4507820 10.12659/MSM.893723 4 3 0 51 Humans|*Glioblastoma|*Case-Control Studies|Brain Neoplasms|RTEL1 protein, human|*DNA Helicases|Genetic Predisposition to Disease|Glioma|Polymorphism, Single Nucleotide|Gene Frequency|Asian Continental Ancestry Group|Genotype|Odds Ratio|Intracellular Signaling Peptides and Proteins|Risk Factors|PHLDB1 protein, human|Nerve Tissue Proteins 41 PHLDB1 25713050 Cancer Epidemiol. Biomarkers Prev. 2015 10.1158/1055-9965.EPI-14-1106 4 0 1 51 *Case-Control Studies|Genome-Wide Association Study|*Glioma|Brain Neoplasms|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Risk Factors|Genotype|Telomerase|DNA Helicases|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins 41 PHPT1 26636774 Angew. Chem. Int. Ed. Engl. 2015 10.1002/anie.201509378 8 0 0 62 Humans|*Cysteine|*Proteins|Selenocysteine|Peptides|Amino Acids|*Biophysical Phenomena|*Chemical Phenomena 42 PHPT1 26537769 J. Int. Med. Res. 2015 10.1177/0300060515587576 3 0 0 62 *Carcinoma, Renal Cell|phosphohistidine|Kidney Neoplasms|Prognosis|Immunohistochemistry|Kaplan-Meier Estimate|Disease-Free Survival|*Cell Nucleus|Biomarkers, Tumor|Phosphoric Monoester Hydrolases 42 PHPT1 25574816 Ups. J. Med. Sci. 2015 PMC4389004 10.3109/03009734.2014.996720 5 24 1 62 *Histones|*Polylysine|phosphohistidine|*Phosphorylation|Histidine|phosphoramidic acid|Phosphoric Acids|Phosphoprotein Phosphatases|*Protein Processing, Post-Translational|Kinetics|Amino Acid Sequence|Peptides|Amides 42 PILRA 26546894 Iran J Allergy Asthma Immunol 2015 2 3 0 23 *Allergens|Egg Hypersensitivity|ovalbumin-alum|Alum Compounds|Ovalbumin|aluminum sulfate|Th2 Cells|Th1 Cells|Adjuvants, Immunologic|Freund's Adjuvant|IL10 protein, human|Interleukin-10|*Macrophages|Cytokines|*Immune System Diseases|Lipopolysaccharides 38 PILRA 26399532 Yi Chuan 2015 10.16288/j.yczz.15-136 0 0 0 23 Swine|Animals|Receptors, Immunologic|*RNA Splicing|Membrane Glycoproteins|Amino Acid Sequence|Immunoglobulin|Liver|Sequence Homology, Amino Acid|Cloning, Molecular 38 PIWIL3 26484274 Genom Data 2015 PMC4583685 10.1016/j.gdata.2015.06.026 16 0 2 21 Male|Humans|Female|Cattle|Mice|Animals|*piRNA|*Oocytes|Argonaute Proteins|Ovary|Testis|Germ Line|TYRP1 protein, human|*Membrane Glycoproteins|*Mammals|Embryogenesis|Gene Expression|Oogenesis|PIWIL2 protein, human|Piwil1 protein, mouse 24 PIWIL3 25818294 Cell Rep 2015 10.1016/j.celrep.2015.02.062 48 0 9 21 Male|Female|Cattle|Animals|Humans|Mice|*piRNA|*Oocytes|Argonaute Proteins|Ovary|Testis|Transposable Elements|TYRP1 protein, human|*Membrane Glycoproteins|*Mammals|Mammalian Embryos|PIWIL2 protein, human|Piwil1 protein, mouse 24 PIWIL3 25802409 RNA 2015 PMC4408798 10.1261/rna.048603.114 11 0 4 21 Male|Humans|Female|Mice|Animals|*RNA Interference|*Tupaia|Argonaute Proteins|piRNA|Germ Line|Gene Silencing|Drosophila|DNA Transposable Elements|Drosophila Proteins|*Mammals|Gene Expression Regulation|Testis|Rfx4 protein, mouse|Regulatory Factor X Transcription Factors 24 Pl15 26365535 Nat Commun 2015 PMC4579568 10.1038/ncomms9179 0 3 2 0 *Cytoplasmic Dyneins|Cryoelectron Microscopy|Dictyostelium|*Microtubules|Dynein|Molecular Motor Proteins|Kinesin|Protein Structure, Tertiary|Protein Binding|Models, Molecular|Binding Sites|Adenosine Triphosphate|Models, Biological 23 PLAC4 26675178 Zhonghua Fu Chan Ke Za Zhi 2015 0 0 0 0 Female|Pregnancy|Humans|*Trisomy|*Alleles|*RNA|*Trisomy 21|Prenatal Diagnosis|*Fetus|*Prenatal Care|Karyotyping|mRNA|Polymorphism, Single Nucleotide 22 PLAC4 26217595 Obstet Gynecol Sci 2015 PMC4515474 10.5468/ogs.2015.58.4.261 1 0 1 0 Female|Pregnancy|Humans|*Down Syndrome|*Trisomy|Prenatal Diagnosis|Alleles|Gene Frequency|Pregnancy Proteins|Placenta|Single Nucleotide Polymorphism|mRNA|Genotype|*Plasma 22 PLCL1 26708285 Atherosclerosis 2015 10.1016/j.atherosclerosis.2015.11.019 17 0 1 51 40 PLCL1 26603167 Immunol. Res. 2015 10.1007/s12026-015-8738-x 3 0 0 51 40 PLCL1 26434682 Sci Rep 2015 PMC4593004 10.1038/srep14762 7 17 1 51 Child|Infant|Humans|Child, Preschool|*Mucocutaneous Lymph Node Syndrome|Genome-Wide Association Study|*Coronary Vessels|Taiwan|*Coronary Aneurysm|*Asian Continental Ancestry Group|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genotypes|Gene Frequency|Case-Control Studies|Databases, Genetic|Cohort Studies|PLCB4 protein, human|Phospholipase C beta 40 PLXDC2 26139848 Mol. Cell Proteomics 2015 PMC4597136 10.1074/mcp.M114.041533 23 1 4 107 29 PLXDC2 25719218 Cancer Biol. Ther. 2015 PMC4622512 10.1080/15384047.2015.1017154 9 0 0 107 Humans|*DNA Methylation|*Laryngeal Neoplasms|*Topoisomerase II|*Squamous Cell Carcinoma of Head and Neck|CpG Islands|Promoter Regions, Genetic|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Decitabine|Azacitidine|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Cell Lineage 29 POTEE 26343451 J. Allergy Clin. Immunol. 2015 PMC4679503 10.1016/j.jaci.2015.06.047 10 11 1 39 *Kaposi Varicelliform Eruption|*Dermatitis, Atopic|*Eczema|Single Nucleotide Polymorphisms|Interferon-gamma|Phenotype|High-Throughput Nucleotide Sequencing 20 POTEE 26258681 PLoS ONE 2015 PMC4530950 10.1371/journal.pone.0135360 7 5 1 39 Humans|Animals|*Schistosoma japonicum|*Interleukin-13|*Fibrosis, Liver|Schistosomiasis japonica|Schistosomiasis|Liver|*Polymorphism, Genetic|China 20 POTEE 25860145 PLoS ONE 2015 PMC4393100 10.1371/journal.pone.0122792 3 6 1 39 Humans|Male|Female|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Testis|Prognosis|Biomarkers, Tumor|Kaplan-Meier Estimate|ROC Curve|Lung|Enzyme-Linked Immunosorbent Assay 20 POU3F1 26687503 Brain Struct Funct 2015 10.1007/s00429-015-1160-2 2 0 0 285 Mice|Animals|*Motor Neuron|Hypoglossal Nerve|Homeodomain Proteins|Spinal Cord|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Repressor Proteins|Tongue|Medulla Oblongata|Forkhead Transcription Factors|*Gene Expression Regulation 138 POU3F1 26484290 Genom Data 2015 PMC4583692 10.1016/j.gdata.2015.06.028 1 1 0 285 Mice|Animals|*Cell Differentiation|*Genome|Pluripotent Stem Cells|*Base Sequence|Embryonic Stem Cells|Transcription Factors|Chromatin Immunoprecipitation|*Nervous System|Signal Transduction|*Neurogenesis|Gene Expression Regulation|*Chromosome Mapping|*Oligonucleotide Array Sequence Analysis 138 POU3F1 25708399 Dev. Growth Differ. 2015 10.1111/dgd.12204 6 0 1 285 Mice|Animals|Embryonic Stem Cells|*Nervous System|Pluripotent Stem Cells|Ectoderm|Mesoderm|Neural Plate|Cell Differentiation|Signal Transduction|Epigenesis, Genetic|Fibroblast Growth Factors|Histones 138 POU3F1 25567987 Nucleic Acids Res. 2015 PMC4333422 10.1093/nar/gku1396 9 24 0 285 Mice|Animals|Humans|*Keratinocytes|Human Induced Pluripotent Stem Cells|Epidermis|Epidermal Cells|*Cell Differentiation|Transcription Factors|*Morphogenesis|Trans-Activators|Phosphoproteins|Gene Expression Regulation, Developmental|Transcription, Genetic|Skin|Chromatin|*Organogenesis 138 PPP1R3A 26593335 Mitochondrion 2015 10.1016/j.mito.2015.11.003 15 5 2 909 *Mitochondrial Dynamics|*Glutamate Dehydrogenase|Cardiomyocyte|Mitochondria, Heart|*Hypoxia|Myocardial Reperfusion Injury|Mitochondrial Membrane Transport Proteins|Cell Hypoxia|Mitochondrial Proteins|Reactive Oxygen Species|Apoptosis|Cell Survival|Membrane Proteins|*Myocardial Ischemia 40 PPP1R3A 26043790 Autophagy 2015 PMC4590604 10.1080/15548627.2015.1052205 44 2 4 909 Mice|Rats|Animals|*Cocaine|*Autophagy|Beclin 1|Endoplasmic Reticulum Stress|Signal Transduction|Apoptosis Regulatory Proteins|*Macrophage Activation|Apoptosis|Microglia 40 PRDM8 26283595 Genes Cells 2015 10.1111/gtc.12274 3 0 0 41 Mice|Animals|*Neocortex|*Neurons|Neurogenesis|Gene Expression Regulation, Developmental|Mice, Knockout|Histone-Lysine N-Methyltransferase|PRDM8 protein, mouse 25 PRDM8 26278982 Mol. Aspects Med. 2015 10.1016/j.mam.2015.08.006 13 0 1 41 Humans|Horses|Animals|polyglucosan|*Myopathies|*Glucans|Glycogen Storage Disease|Glycogen|Muscle Weakness|Muscle, Skeletal|Muscle Fibers, Skeletal|Polysaccharides|Cardiomyopathy|Inclusion Bodies|Mutations|PRKAG2 protein, human|AMP-Activated Protein Kinases|NHLRC1 protein, human|Carrier Proteins|EPM2A protein, human|Protein Tyrosine Phosphatases, Non-Receptor 25 PRDM8 26023183 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4466745 10.1073/pnas.1505870112 10 0 1 41 Mice|Animals|*Cell Survival|*Retinal Bipolar Cells|Amacrine Cell|Retina|Retinal Rod Photoreceptor Cells|Retinal Cone Photoreceptor Cells|Night blindness, congenital stationary|Night Blindness|Electroretinography|Eye Diseases, Hereditary|Genetic Diseases, X-Linked|Cell Differentiation|Myopia|Transcription Factor|Mice, Knockout|*Complement Factor B|Diabetes Mellitus, Type 2|PRDM8 protein, mouse 25 PRICKLE2 26257100 Sci Rep 2015 PMC4530445 10.1038/srep12916 5 17 1 83 Animals|*Cell Polarity|*Disks Large Homolog 4 Protein|Synapse|Postsynaptic Density|Neurons|Guanylate Kinases|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|Membrane Proteins|Hippocampus|*Transcription Factors|Cells, Cultured|Tumor Suppressor Proteins|Brain 50 PRICKLE2 26175546 Acta Histochem Cytochem 2015 PMC4427563 10.1267/ahc.14046 0 9 0 83 Rats|Animals|*Ameloblasts|*Incisor|*Cell Polarity|Enamel Organ|Amelogenesis|Odontogenesis|Cell Differentiation|Membrane Protein|Cytoplasm|Cells, Epithelial 50 PRICKLE2 25763846 PLoS Genet. 2015 PMC4357451 10.1371/journal.pgen.1005022 27 19 3 83 Humans|Animals|Mice|ubiquitin isopeptidase|*Seizures|Ubiquitination|Ubiquitin Thiolesterase|Mutations|Phenotype|Proteolysis|Cell Proliferation|Cell Line, Tumor|Zebrafish|Genetic Testing|Ubiquitin-Specific Proteases|USP9X protein, human|Usp9x protein, mouse|Endopeptidases|Prickle2 protein, mouse|Membrane Proteins|LIM Domain Proteins 50 PRIMA1 26712693 Clin. Cancer Res. 2015 PMC4867243 10.1158/1078-0432.CCR-15-1927 8 38 0 187 Humans|Male|TP53 protein, human|*Tumor Suppressor Protein p53|2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one|*Prostate|*Prostate Cancer|*Bridged Bicyclo Compounds, Heterocyclic|*Aza Compounds|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Mutation|CD24 protein, human|CD24 Antigen 67 PRIMA1 26697857 J. Mol. Neurosci. 2015 10.1007/s12031-015-0699-y 0 0 0 187 Mice|Animals|Humans|Infant|*mRNA|*Tauopathy|*Hippocampus|tau Proteins|Mice, Transgenic|Memory Deficits|Alzheimer Disease|Acetylcholinesterase|Choline Acetyltransferase|Disease Models, Animal|Butyrylcholinesterase|Aging|Phosphorylation 67 PRIMA1 26482433 BMC Cancer 2015 PMC4612409 10.1186/s12885-015-1687-x 20 2 1 187 *DNA Methylation|*B-DNA|*Adenoma|*Colorectal Cancer|SFRP1 protein, human|*Intercellular Signaling Peptides and Proteins|*Membrane Proteins|Carcinoma|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Processes, Epigenetic|Colonic Neoplasms|RNA, Messenger 67 PRIMA1 26378048 Oncotarget 2015 PMC4694938 10.18632/oncotarget.5612 6 36 1 187 Humans|IGFBP3 protein, human|*Insulin-Like Growth Factor Binding Protein 3|TP53 protein, human|*Tumor Suppressor Protein p53|*DNA Damage|Apoptosis|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Downregulation|Cell Line, Tumor|Upregulation|siRNA|Etoposide|Doxorubicin 67 PRIMA1 26339676 Ann Clin Transl Neurol 2015 PMC4554443 10.1002/acn3.224 3 2 0 187 *Epilepsy, Frontal Lobe|*Mutation|Nicotinic Acetylcholine Receptor|Pedigree|Mutation, Missense|Phenotype 67 PRIMA1 26011298 Sci Rep 2015 PMC4443767 10.1038/srep10356 5 6 0 187 *Carcinoma, Non-Small-Cell Lung|TP53 protein, human|*Tumor Suppressor Protein p53|*Lung Cancer|Cell Line, Tumor|Adaptor Proteins, Signal Transducing|Phosphoproteins|Apoptosis|Antineoplastic Agents|TP53 Gene|Signal Transduction|*Complement Factor B|3'-(1-butylphosphoryl)adenosine|Transcription Factors 67 PRSS56 26701169 Brain Struct Funct 2015 10.1007/s00429-015-1171-z 10 0 0 17 Animals|Mice|*Neurogenesis|Ventricles, Lateral|Neural Stem Cells|Adult Stem Cells|Cell Lineage|Hippocampus 26 PRSS56 25587058 Invest. Ophthalmol. Vis. Sci. 2015 10.1167/iovs.14-14880 12 0 0 17 Humans|Genome-Wide Association Study|Myopia 12|*Myopia|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|RASGRF1 protein, human|rasGRF1|Exome|Eye Proteins|Genotype|Mutation 26 prune2 26238782 Cancer Res. 2015 PMC4573907 10.1158/0008-5472.CAN-15-0702 61 1 3 110 *Carcinoma, Merkel Cell|*Merkel cell polyomavirus|Precision Medicine|Tumor Virus Infections|Polyomavirus Infections|DNA Mutational Analysis|Skin Neoplasms|Mutation|Oncogenes|*Carcinoma|Biomarkers, Tumor 34 prune2 26080435 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4500257 10.1073/pnas.1507882112 60 1 9 110 Male|Humans|Mice|Animals|*RNA, Long Noncoding|prostate cancer antigen 3, human|*Antigens, Neoplasm|*Prostate Cancer|Prostate|*Genes, Neoplasm|Neoplasm Proteins|*Introns|Cell Line, Tumor|*Genes, Regulator|*Transcription Factors|Editing, RNA|Cell Proliferation 34 prune2 25611382 Cell Death Dis 2015 PMC4669766 10.1038/cddis.2014.568 5 81 0 110 Humans|*Proto-Oncogene Proteins c-akt|*Apoptosis|FOXO3 protein, human|Forkhead Box Protein O3|Apoptosis Regulatory Proteins|Bcl-2-Like Protein 11|Proto-Oncogene Proteins|Phosphorylation|Signal Pathway|Phosphatidylinositol 3-Kinases|Forkhead Transcription Factors|Cisplatin|Membrane Proteins|Neuroblastoma|Cell Line, Tumor|Antineoplastic Agents|Downregulation|RNA, Small Interfering 34 PTAFR 29354667 Genes Dis 2015 PMC5773056 10.1016/j.gendis.2015.06.002 2 1 0 671 Humans|Child|Mice|Animals|*Body Weight|Obesity|Dietary Fat|Energy Intake|Feeding Behavior|Eating|Dietary Carbohydrates|Body Composition|Adipose Tissue|platelet activating factor receptor|*Platelet Membrane Glycoproteins|High-Fat Diets|Energy Metabolism|*Receptors, G-Protein-Coupled 39 PTOV1 26499835 Mol. Cell Proteomics 2015 PMC4762622 10.1074/mcp.M115.050773 2 2 0 127 Peptidylprolyl Isomerase|NIMA-Interacting Peptidylprolyl Isomerase|Phosphorylation|Protein Phosphatase 2|Protein Binding 38 PTOV1 26305455 PLoS ONE 2015 PMC4549246 10.1371/journal.pone.0136448 4 2 1 127 Humans|Male|*Nasopharyngeal Carcinoma|*Prognosis|*Disease Progression|Immunohistochemistry|Nasopharyngeal Neoplasms|Biomarkers, Tumor|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|*Prostatic Neoplasms|Cell Line, Tumor|Kaplan-Meier Estimate|Neoplasm Staging|RNA, Messenger|PTOV1 protein, human 38 PTOV1 26156556 RNA Biol 2015 PMC4615771 10.1080/15476286.2015.1060394 11 1 1 127 Humans|Mice|Animals|*RNA-Binding Motif|DNA-Binding Proteins|Nucleic Acid Conformation|High Mobility Group Proteins|DNA|Amino Acid Sequence|Binding Sites|RNA|Protein Binding|Electrophoretic Mobility Shift Assay|Models, Molecular|PTOV1 protein, human|Neoplasm Proteins|Biomarkers, Tumor|BAZ2A protein, human|Chromosomal Proteins, Non-Histone 38 PTOV1 25634174 Medicine (Baltimore) 2015 PMC4602939 10.1097/MD.0000000000000423 3 4 0 127 Humans|Male|*Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|*Disease Progression|Biomarkers, Tumor|Immunohistochemistry|Liver|Neoplasm Staging|Neoplasm Proteins|Cell Line, Tumor|*Prostate Cancer|Kaplan-Meier Estimate|Upregulation|mRNA|Cell Proliferation|Real Time Polymerase Chain Reaction|PTOV1 protein, human 38 PTPRCAP 25716735 Biochemistry Mosc. 2015 10.1134/S0006297914120153 3 0 1 34 *Epitope Mapping|PTPRC protein, human|Leukocyte Common Antigens|Membrane Proteins|Intracellular Signaling Peptides and Proteins|*Lymphocyte|*Phosphatase, Phosphoprotein|Phosphoproteins|Phosphorylation|Lymphocyte Activation|Amino Acid Sequence|Epitopes|Antibodies, Monoclonal 48 PTPRE 26421924 PLoS Pathog. 2015 PMC4589396 10.1371/journal.ppat.1005183 8 29 1 152 Humans|*Hepacivirus|*Hepatitis C|*Lymphocyte Activation|Hepatitis C Antibodies|Viral Envelope Proteins|RNA, Viral|PTPRE protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 4|Viremia|Signal Transduction|Hepatocytes 70 PTPRM 26683690 PLoS ONE 2015 PMC4684329 10.1371/journal.pone.0143826 12 11 1 98 *Epigenome|*Lung Cancer|Non-Small-Cell Lung Carcinomas|CpG Islands|DNA Methylation|Promoter Regions, Genetic|Adenocarcinoma|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Oligonucleotide Array Sequence Analysis|cadherin 5|Cadherins|Gene Expression Profiling|Antigens, CD 52 PTPRM 26458310 Neoplasma 2015 10.4149/neo_2015_117 7 0 0 98 *Polymorphism, Single Nucleotide|Protein Interaction Maps|*Oncogenes|*Lung Cancer|Gene Expression Profiling|Gene Regulatory Networks|Computational Biology|Gene Expression Regulation, Neoplastic|Transcription Factors|Genes, Regulator|Downregulation|Up-Regulation|mRNA 52 PTPRM 25910225 Sci Rep 2015 PMC5386118 10.1038/srep09633 7 4 0 98 *Adenoma|*Colorectal Carcinoma|*Carcinoma|DNA Methylation|Promoter Regions, Genetic|DNA Copy Number Variations|Gene Expression Regulation, Neoplastic|Oligonucleotide Microarray|Epigenetic|Intestinal Mucosa 52 PTPRM 25850409 Histochem. Cell Biol. 2015 PMC4468792 10.1007/s00418-015-1319-1 1 3 0 98 Mice|Animals|*Osteocytes|Mechanotransduction, Cellular|Osteoblasts|Bone|Cell Differentiation|*Protein Tyrosine Phosphatase|*Biomarkers|fibroblast growth factor 23|Fibroblast Growth Factors|DMP1 protein, human|Extracellular Matrix Proteins|Osteocalcin|Bone Marrow Cell|Phosphoproteins|Cortical Bone|Receptor-Like Protein Tyrosine Phosphatases, Class 2 52 PTPRM 25639731 Stem Cells 2015 PMC4409488 10.1002/stem.1962 17 35 1 98 *Stem Cells|Limbus Corneae|Epithelium, Corneal|GJA1 protein, human|Connexin43|Gap Junctions|Stem Cell Niche|CDH1 protein, human|E Cadherin|Epithelial Cells|Cell Communication|Cells, Cultured|Keratinocytes|Cell Adhesion|Cell Proliferation|RNA, Micro|Antigens, CD 52 PURG 25821059 Wien. Klin. Wochenschr. 2015 10.1007/s00508-015-0777-8 0 0 0 44 Male|Humans|Retrospective Studies|*Intervention, Percutaneous Coronary|Resuscitation, Cardio-Pulmonary|Arrest, Cardiac|Coronary Occlusion|Coronary Angiography|Treatment Outcome|Emergency Service, Hospital 36 PYHIN1 25895113 Inflamm. Bowel Dis. 2015 PMC4450895 10.1097/MIB.0000000000000381 8 0 2 57 Child|Humans|*Exome|Genome-Wide Association Study|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn Disease|Predispositions, Genetic|*Autoimmune Disease 20 PYHIN1 25665578 Mol. Syst. Biol. 2015 PMC4358659 10.15252/msb.20145808 32 40 2 57 Humans|*DNA, Viral|Phosphoproteins|Nuclear Proteins|Cell Nucleus|Herpesvirus 1, Human|Virus Replication|Gene Expression Regulation, Viral|Host-Pathogen Interactions|Immunity, Innate|*Immunologic Factors|Proteomics|Signal Transduction 20 RAD54B 26694360 Int J Mol Sci 2015 PMC4691157 10.3390/ijms161226214 4 10 1 120 Male|Mice|Animals|*DNA Breaks, Double-Stranded|*Spermatids|Meiosis|*Mice, SCID|DNA Repair|DNA End-Joining Repair|RAD54B protein, human|Nuclear Proteins|Histones|DNA-Activated Protein Kinase|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|DNA Helicases|Poly(ADP-ribose) Polymerases|Spermatocytes|DNA-Binding Proteins|meiotic recombination protein SPO11|Endodeoxyribonucleases 67 RAP1GDS1 26598509 Cardiovasc. Res. 2015 10.1093/cvr/cvv253 3 6 0 152 *Hydroxymethylglutaryl-CoA Reductase Inhibitors|*Up-Regulation|*Endothelial Cells|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|Heptanoic Acids|Pravastatin|Atorvastatin|Pyrroles|*Integrins|Signal Transduction|*Transcriptional Activation|Angiotensin II|Cholesterol|Oxidative Stress 48 RAP1GDS1 26004809 Leuk. Res. 2015 10.1016/j.leukres.2015.04.014 5 0 1 152 nuclear pore complex protein 98|*Translocation, Genetic|Nuclear Pore Complex Proteins|Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|*Leukemia, T-Cell|Nuclear Proteins|Karyotyping|In Situ Hybridization, Fluorescence|RAP1GDS1 protein, human|Guanine Nucleotide Exchange Factors|Immunophenotyping 48 RAPGEF6 26057047 Transl Psychiatry 2015 PMC4490285 10.1038/tp.2015.75 6 15 1 96 Mice|Animals|*Amygdala|Fear|Pyramidal Neurons|*Schizophrenia|Hippocampus|Region, Hippocampal CA3|Long-Term Potentiation|Memory|Cortex, Prefrontal|Mice, Knockout|Dendrites|Proto-Oncogene Proteins c-fos|Rapgef6 protein, mouse|Guanine Nucleotide Exchange Factors 25 RASGEF1B 26114601 Pediatr Int 2015 10.1111/ped.12742 0 0 0 25 Child|Humans|Female|Chromosome 4q- Syndrome|*Chromosome Deletion|*Chromosome Disorders|*Disease, Polycystic Kidney|Abnormalities, Multiple|Developmental Disabilities|Intellectual Disability|*Chromosomes, Human, Pair 4|Chromosome Banding|Phenotype|Syndrome 28 RASGEF1B 25774221 Mol Cytogenet 2015 PMC4359765 10.1186/s13039-015-0118-7 2 1 1 25 Humans|Hungary|Chromosome 4q- Syndrome|*Chromosome Deletion|*Chromosome Disorders|*Chromosomes, Human, Pair 4|Facies|Phenotype|Comparative Genomic Hybridization|Intellectual Disability|Abnormalities, Multiple|Hypotonia|*Phenotypic Variability|Syndrome 28 RAX2 26578700 Plant Cell 2015 PMC4682308 10.1105/tpc.15.00829 19 0 2 14 *Arabidopsis|*Transcription Factor|Arabidopsis Proteins|Meristems|Auxin|Shoot, Plant|Gene Expression Regulation, Plant|Genes, Plant|Phenotype|Membrane Transport Proteins|Mutation|WRKY71 protein, Arabidopsis 25 RAX2 25986607 Mol. Cell. Biol. 2015 PMC4524118 10.1128/MCB.00048-15 15 1 1 14 Mice|Animals|Photoreceptor, Cone|Homeodomain Proteins|Retinal Rod Photoreceptor Cells|Trans-Activators|Rhodopsin|*Cell Differentiation|Eye Proteins|Retina|Orphan Nuclear Receptors|Promoter Regions, Genetic|Mice, Knockout|Rax protein, mouse|Transcription Factors 25 RAX2 25968316 Development 2015 PMC4440930 10.1242/dev.123653 12 22 0 14 Animals|Chick Embryo|Prospective Studies|*Lens, Crystalline|Ectoderm|*Retina|Bone Morphogenetic Proteins|Signal Transduction|Cell Differentiation|Gene Expression Regulation, Developmental|Fibroblast Growth Factors|*Lenses 25 RAX2 25953852 Nucleic Acids Res. 2015 PMC4551904 10.1093/nar/gkv411 0 0 0 14 Animals|Polyadenylation|RNA Isoforms|Alternative Splicing|Sequence Analysis, RNA|mRNA|3' Untranslated Regions|Exons|Gene Expression Profiling|Transcriptomes|Promoter Regions, Genetic 25 RAX2 25789692 JAMA Ophthalmol 2015 10.1001/jamaophthalmol.2015.0357 7 0 0 14 Humans|*Retinal Dystrophy|Retinitis Pigmentosa|Electroretinography|Fluorescein Angiography|Pedigree|Genes, Dominant|DNA Mutational Analysis|Eye Proteins|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Tomography, Optical Coherence|Phenotype|Visual Acuity|Mutation|Mutation, Missense 25 REG1B 25768000 Int. J. Biol. Markers 2015 10.5301/jbm.5000133 1 6 0 24 Humans|*HCT116 Cell|*Colon Cancer|*Gene Silencing|Cell Proliferation|shRNA|Cell Movement|Colorectal Carcinoma|Apoptosis|Downregulation|Gene Knockdown Techniques|Gene Expression Regulation, Neoplastic|Up-Regulation|*Neoplastic Processes 36 REG1B 25767811 J Diabetes Res 2015 PMC4342170 10.1155/2015/173058 13 40 2 24 Humans|Rats|Animals|*Glucocorticoids|*Interleukin-6|STAT3 protein, human|STAT3 Transcription Factor|*Promoter Regions, Genetic|Lithostathine|Transductions, Signal|Upregulation|*Pancreas 36 Resp18 25561468 Mol. Cell. Biol. 2015 PMC4333099 10.1128/MCB.00994-14 3 2 0 423 *Insulin|*Secretory Vesicles|*Dimerization|ICA512|*Endoplasmic Reticulum|*Insulin, Regular, Human|Islets of Langerhans|regulated endocrine secretory protein 18|Nerve Tissue Proteins|Cytoplasmic Granules|Protein Tyrosine Phosphatase|Membrane Proteins|Cytosol|Autoantigens|Signal Transduction|Amino Acid Sequence|Glycosylation 23 RHBDF1 26109405 Sci Rep 2015 PMC4479803 10.1038/srep11559 0 52 0 79 Humans|Animals|*Proteasome Endopeptidase Complex|Drosophila melanogaster|*Endoplasmic Reticulum Stress|Tunicamycin|HTT protein, human|Huntingtin Protein|Molecular Chaperones|Ubiquitination|Endoplasmic Reticulum|Thapsigargin|RNA Interference|RNA, Small Interfering|Downregulation 30 RNF39 26534935 Physiol. Genomics 2015 PMC4757024 10.1152/physiolgenomics.00067.2015 4 0 1 8 Female|Humans|*Coronary Artery Disease|*Genetic Loci|*European Continental Ancestry Group|Coronary Angiography|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Risk Factors|Genetic Marker|Odds Ratio|Genotype|RNF39 protein, human|Immediate-Early Proteins 22 RNF39 26405558 Lupus Sci Med 2015 PMC4577980 10.1136/lupus-2015-000101 18 2 1 8 *CD4-Positive T-Lymphocytes|*DNA Methylation|*B-DNA|*Lupus Erythematosus, Systemic|*Exanthema|Lupus Nephritis|*Epigenetic|Epigenesis, Genetic 22 RTTN 26715629 Mol. Biol. Evol. 2015 PMC4776707 10.1093/molbev/msv334 33 0 1 72 Humans|*Selection, Genetic|*Genomics|Genetics, Population|Gene Frequency|Biological Adaptation|Genome, Human|Genetic Drift|Genetic Variation|Adaptation, Physiological|Software|Multifactorial Inheritance|Polymorphism, Single Nucleotide|Acclimatization|Asia|Africa|Europe 21 RTTN 26608784 Am. J. Hum. Genet. 2015 PMC4678428 10.1016/j.ajhg.2015.10.012 8 0 0 72 Humans|Autosomal Recessive Primary Microcephaly|*Microcephaly|Canada|*Dwarfism|*Mutations|Pituitary dwarfism 1|Homozygote|Exome|Phenotype|Brain|Polymicrogyria|Pedigree|Exon|Facies|Carrier Proteins|Cell Cycle Proteins|Mutation, Missense 21 SAMSN1 26020268 PLoS ONE 2015 PMC4447437 10.1371/journal.pone.0127828 10 2 0 51 Humans|Mice|Animals|*Mice, Inbred C57BL|*Multiple Myeloma|Monoclonal Gammopathy of Undetermined Significance|Bone Marrow Cells|Stromal Cells|*Sequencing, Whole Genome|Cell Line, Tumor|Bone Marrow Stromal Cells|Disease Progression|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport 25 SAMSN1 25805236 Ann. Surg. Oncol. 2015 10.1245/s10434-015-4524-1 5 0 0 51 *Carcinoma, Hepatocellular|*Liver Neoplasms|Prognosis|Neoplasm Recurrence, Local|Biomarkers, Tumor|Neoplasm Staging|Gene Expression Regulation, Neoplastic|Cell Proliferation|Real-Time Polymerase Chain Reaction|Survival Rate|RNA, Messenger|DNA Methylation|Cell Movement|Tumor Cells, Cultured|Promoter Regions, Genetic|Apoptosis|Immunoenzyme Techniques|*Phenotype 25 SBSN 26662136 Rom J Morphol Embryol 2015 1 0 0 57 Male|*Knee Joint|Posterior Cruciate Ligament|Tibia|Arthroscopy|Capsule, Joint|Cadaver|Tibial Nerve|Popliteal Artery|*Plastination|Peripheral Nerves 23 SBSN 25935274 J. Vasc. Surg. 2015 PMC4627903 10.1016/j.jvs.2014.12.052 4 9 0 57 Humans|*Veins|Neointima|Muscle, Smooth, Vascular|Myocytes, Smooth Muscle|Graft Occlusion, Vascular|Vascular Grafting|Hyperplasia|Cell Proliferation|Cell Movement|Cells, Cultured|Transfection|Receptors, Scavenger|SCARA5 protein, human|Scavenger Receptors, Class A|SBSN protein, human|Antigens, Differentiation|Neoplasm Proteins 23 SCAF1 26215952 J. Clin. Oncol. 2015 10.1200/JCO.2015.62.0674 55 0 3 104 Carcinoma, Non-Small-Cell Lung|Crizotinib|Proto-Oncogene Proteins c-met|Lung Neoplasms|*Sequencing, Next-Generation|Exons|Protein Kinase Inhibitors|Adenocarcinoma|Mutation|*Carcinoma|Pyrazoles|Pyridines 28 Scara3 26387537 Oncogene 2015 PMC4893634 10.1038/onc.2015.335 12 9 1 1145 Male|Animals|Histone Acetyltransferases|Drosophila Proteins|Drosophila|Nuclear Proteins|Histones|Acetylation|Embryonic Development|Cell Differentiation|mof protein, Drosophila 37 Scara3 26378933 PLoS ONE 2015 PMC4574561 10.1371/journal.pone.0138248 2 29 1 1145 Humans|*Bortezomib|*Multiple Myeloma|Hematopoietic Stem Cell Transplantation|Transplantation, Autologous|TNFRSF10A protein, human|Receptors, TNF-Related Apoptosis-Inducing Ligand|Boronic Acids|TNFRSF10B protein, human|Pyrazines|Lenalidomide|Antineoplastic Agents|*Upregulation|Apoptosis|Cell Line, Tumor|Chromosome Deletion|*Transcriptional Activation|Tumor Necrosis Factor Decoy Receptors 37 Scara3 25956032 Am. J. Pathol. 2015 PMC4484220 10.1016/j.ajpath.2015.03.015 9 3 2 1145 Humans|Male|Mice|Animals|*Prostate Cancer|3' Untranslated Region|Downregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Up-Regulation|Cell Cycle|Tumor Burden|MIRN650 microRNA, human 37 SCGB1D2 26014856 Int. J. Cancer 2015 PMC4744995 10.1002/ijc.29616 6 7 0 18 Humans|*Chromatin|*Binding Sites|*Genes, Homeobox|Homeodomain Proteins|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Cell Line, Tumor|Transcription Factor|Chromatin Immunoprecipitation|Cell Proliferation|Gene Expression Profiling|DNA Repair|HOXB7 protein, human 156 SCPEP1 26662984 Adv. Exp. Med. Biol. 2015 10.1007/978-3-319-22380-3_2 7 0 1 445 *RNA, Micro|RNA-Binding Proteins|DICER1 protein, human|Ribonuclease III|DEAD-box RNA Helicases|Argonaute Proteins|RNA-Induced Silencing Complex|RNA Processing, Post-Transcriptional|RNA Interference|Karyopherins|Gene Silencing 47 SCPEP1 26578072 J. Anim. Breed. Genet. 2015 10.1111/jbg.12189 9 0 1 445 Swine|Animals|*Genome-Wide Association Study|Italy|*Breeding|Quantitative Trait Loci|Sus scrofa|Genotype|SNPs|Meat|Haplotypes|Crosses, Genetic|Phenotype|Muscle, Skeletal 47 SCPEP1 26443379 RNA 2015 PMC4647457 10.1261/rna.053207.115 9 0 0 445 Animals|Humans|*Phosphorylation|AGO2 protein, human|*Argonaute Proteins|RNA Interference|Ribonuclease III|DEAD-box RNA Helicases|MicroRNAs|Cytoplasmic Granules|Gene Silencing 47 SCPEP1 26221025 Biochem. J. 2015 10.1042/BJ20150445 9 1 0 445 Humans|*RNA Interference|*miRNA|Dengue Virus|Dengue|Virus Replication|trans-activation responsive RNA-binding protein|RNA-Binding Proteins|RNA-Induced Silencing Complex|Viral Nonstructural Proteins|RNA Helicases|mRNA|Cells, 293T|Host-Pathogen Interactions|Downregulation 47 SCPEP1 26188282 Cancer Lett. 2015 10.1016/j.canlet.2015.07.010 11 2 0 445 *Carcinoma, Hepatocellular|*RNA, Micro|*Liver Neoplasms|*Gene Silencing|Argonaute Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|*RNA-Binding Proteins|mRNA|3' Untranslated Regions|Hep G2 Cells|Oncogenes|Cell Line, Tumor|Binding Sites 47 SCPEP1 25972178 J. Neurosci. 2015 PMC6705439 10.1523/JNEUROSCI.4794-14.2015 11 0 0 445 Mice|Animals|*miRNA|*RNA-Induced Silencing Complex|Experimental Autoimmune Encephalomyelitis|Myelin-Oligodendrocyte Glycoprotein|Central Nervous System|AGO2 protein, human|Argonaute Proteins|Multiple Sclerosis|Mice, Inbred C57BL|Gene Expression Regulation|Disease Models, Animal|Cell Differentiation|Cytokines 47 SCPEP1 25630541 Wiley Interdiscip Rev RNA 2015 PMC7169789 10.1002/wrna.1272 14 4 2 445 Humans|*RNA, Double-Stranded|trans-activation responsive RNA-binding protein|*Double-Stranded RNA-Binding Proteins|Double-Stranded RNA Binding Domain|Ribonuclease III|RNA Interference|MicroRNAs|RNA-Induced Silencing Complex|*Noncoding RNA|RNA, Small Interfering|Protein Binding|eIF-2 Kinase|Phosphorylation|HeLa Cells 47 SCRN1 26510499 Mol. Biol. Cell 2015 PMC4694765 10.1091/mbc.E15-06-0329 13 32 1 65 *Oculocerebrorenal Syndrome|*Protein Transport|trans Golgi Network|Endosomes|Phosphoric Monoester Hydrolases|Receptor, Mannose 6 Phosphate|Endocytosis|*Proteins|PtdIns|*Membrane|*Cell Movement 21 SCRN1 25886259 Proteomics 2015 10.1002/pmic.201400359 3 0 1 65 Pregnancy|Male|Female|Animals|Humans|Rats|*Rats, Sprague-Dawley|*Proteomics|*Obesity|*Fetal Programming|Prenatal Nutritional Physiological Phenomena|Body Weight|Prenatal Exposure Delayed Effects|Animals, Newborn|Fetal Growth Retardation|Food|*Biomarkers|SCRN1 protein, human|Nerve Tissue Proteins 21 SCRN1 25814779 Dis. Markers 2015 PMC4357136 10.1155/2015/230703 5 11 1 65 *Matrix Metalloproteinase 2|*Colon Cancer|*Colon|Matrix Metalloproteinase 9|*Exocytosis|mRNA|Cell Proliferation|Cell Movement|*Neoplastic Processes|*Disease Progression 21 SCRN1 25667921 Biomed Res Int 2015 PMC4312578 10.1155/2015/454256 14 3 5 65 Humans|Male|*Prostate|*Two-Dimensional Difference Gel Electrophoresis|Neoplasm Recurrence, Local|*Prostate Cancer|*Prognosis|*Mass Spectrometry|Immunohistochemistry|Biomarkers, Tumor|Proteomics|Proteins|Western Blot 21 SEC14L2 26598896 J. Nutr. Sci. Vitaminol. 2015 10.3177/jnsv.61.S76 1 1 0 336 Animals|*Vitamin E|*Phosphatidylinositol 3-Kinases|*Signal Transduction|lipid transfer protein|Carrier Proteins|*Gene Expression|Phosphatidylinositol 3-Kinase|Proto-Oncogene Proteins c-akt|Phosphorylation|Phosphatidylinositol|Trans-Activators|Lipid Metabolism|*Biochemical Phenomena|*Eicosanoids|Membrane Lipids|Oxidation-Reduction 55 SEC14L2 26441247 Nat Rev Gastroenterol Hepatol 2015 10.1038/nrgastro.2015.170 1 0 0 336 Humans|*Hepatitis B|Hepacivirus|Carcinoma, Hepatocellular|*Cell Culture|Liver Neoplasms|Hepatitis C|Virus Replication|RNA, Viral|Genotype|*Immunologic Tests 55 SEC14L2 26266980 Nature 2015 PMC4632207 10.1038/nature14899 34 8 7 336 Humans|Hepatitis C virus|Replicon|Hepatitis C|Virus Replication|RNA, Viral|*Cell Division|*Cell Culture|Genotype|Hepatoma|Genome, Viral|Liver Neoplasms|Mutations|Cell Line, Tumor|Complementary DNA|*Immunologic Tests|SEC14L2 protein, human|Carrier Proteins|Lipoproteins 55 SERPINI1 25859180 Front Neurosci 2015 PMC4374456 10.3389/fnins.2015.00100 6 2 1 165 Animals|*Neurons|Cerebral Cortex|*Neurogenesis 31 SETMAR 26437079 PLoS ONE 2015 PMC4593633 10.1371/journal.pone.0139418 5 14 1 173 *PR-SET Domains|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|Histone H3|DNA Repair|SET protein, human|Histone Chaperones|DNA Replication|DNA Damage|Transcription Factors|Transposase|DNA End-Joining Repair|DNA-Binding Proteins|DNA|Lysine 44 SETMAR 25795785 J. 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Reprod. 2015 PMC4573451 10.1093/humrep/dev180 9 0 1 105 Humans|Male|*Cryptorchidism|*Genetic Loci|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genotype|*Cytoskeleton|Testis|*Microtubules 23 SHROOM2 26101221 J. Cell Biol. 2015 PMC4477863 10.1083/jcb.201412008 19 80 3 47 Humans|ROCK1 protein, human|rho-Associated Kinase|Phosphorylation|Substrate Specificity|Mass Spectrometry|Proteomics|Amino Acid Sequence|Protein Kinase Inhibitors|HeLa Cells|AKT1 protein, human|Protein Kinase B|PAK7 protein, human 26 SKOR1 26498245 Sleep Med. 2015 10.1016/j.sleep.2015.05.015 0 1 0 30 Wisconsin|Nocturnal Myoclonus Syndrome|Restless Legs Syndrome|*Sleep|*Cohort Studies|Polysomnography|Ferritins 24 SKOR1 26498236 Sleep Med. 2015 PMC4621485 10.1016/j.sleep.2015.07.017 2 2 0 30 Humans|Aged|Nocturnal Myoclonus Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|Restless Legs Syndrome|MAP Kinase Kinase 5|Homeodomain Proteins|Single Nucleotide Polymorphisms|*Polysomnography|Transcription Factors|Genetic Predisposition to Disease|*Sleep|Nerve Tissue Proteins|Gene Frequency|Neoplasm Proteins|Cohort Studies|Case-Control Studies|Receptor-Like Protein Tyrosine Phosphatases, Class 2 24 SKOR1 26449484 Genome Med 2015 PMC4599317 10.1186/s13073-015-0225-4 27 3 2 30 *DNA Methylation|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|*Promoter Regions, Genetic|*Obesity|CpG Islands|Epigenetic|*Regulatory Sequences, Nucleic Acid|Epigenesis, Genetic|RNA, Messenger 24 SKOR1 26298793 Sleep Med. 2015 10.1016/j.sleep.2015.06.002 5 1 0 30 *Restless Legs Syndrome|Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Homeodomain Proteins|Transcription Factors|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Case-Control Studies|Neoplasm Proteins|Receptor-Like Protein Tyrosine Phosphatases, Class 2 24 SKOR1 25817513 Parkinsonism Relat. Disord. 2015 PMC4441838 10.1016/j.parkreldis.2015.03.010 1 1 0 30 *Restless Legs Syndrome|*Parkinson Disease|*Genetic Markers|Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Homeodomain Proteins|Transcription Factors|Genome-Wide Association Study|Nerve Tissue Proteins|Polymorphism, Single Nucleotide|Neoplasm Proteins|Alleles|Case-Control Studies|Receptor-Like Protein Tyrosine Phosphatases, Class 2 24 SLC16A12 26376857 J. Am. Soc. Nephrol. 2015 PMC4849831 10.1681/ASN.2015040411 7 3 0 24 Humans|HEK293 Cells|glycocyamine|Renal Glucosuria|*Mutation|SLC5A2 protein, human|Sodium-Glucose Transporter 2|*Glycosuria|*Glycine|Cataract|Heterozygote|Pedigree|Monocarboxylic Acid Transporters|Phenotype|Kidney 24 SLC16A12 25625310 Int. J. Oncol. 2015 10.3892/ijo.2015.2855 1 0 0 24 Humans|Male|In Situ Hybridization, Fluorescence|*Prevalence|*Prostate Cancer|*Chromosome Aberrations|Proto-Oncogene Proteins c-ets|Oncogene Proteins, Fusion|TMPRSS2 protein, human|Serine Endopeptidases|Gene Fusion|Transcription Factor|Trans-Activators|Androgens 24 SLC16A9 26026093 Anticancer Res. 2015 2 1 0 89 *Central Nervous System Neoplasms|*Gene Expression Profiling|*Lymphoma, Non-Hodgkin|*Microarray Analysis|Lymphoma, Large B-Cell, Diffuse|B-Lymphocytes|Gene Expression Regulation, Neoplastic 30 SLC16A9 25569235 PLoS Genet. 2015 PMC4287344 10.1371/journal.pgen.1004835 24 3 8 89 Humans|*Genome-Wide Association Study|*Exome|*Phenotypes|Quantitative Trait Loci|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Metabolome|Genotype|*Genetic Testing|Nuclear Magnetic Resonance 30 SLC22A9 26239079 Pharmacogenomics J. 2015 10.1038/tpj.2015.55 7 0 1 139 Humans|*Pravastatin|*Organic Anion Transporters|Organic Anion Transporters, Sodium-Independent|*Liver|Solute Carrier Organic Anion Transporter Family Member 1B3|*Biological Transport|Liver-Specific Organic Anion Transporter 1|Hepatocytes|*Membrane Transport Proteins|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Estrone|Proteomics|SLC22A9 protein, human 30 SLC22A9 26170735 Korean J. Physiol. Pharmacol. 2015 PMC4499643 10.4196/kjpp.2015.19.4.319 1 0 0 139 Humans|Female|Republic of Korea|*Osteoporosis|SNPs|Organic Anion Transporters|estrone sulfate|Estrone|Exon|Estrogens|Amino Acid Substitution|SLC22A9 protein, human|Organic Anion Transporters, Sodium-Independent 30 SLC25A24 26165595 Structure 2015 PMC4526376 10.1016/j.str.2015.06.004 6 8 0 148 *MgATP|*Mitochondria|ADP,ATP Carrier|Mitochondrial Proteins|Antiporters|Membrane Transport Proteins|Amino Acid Sequence|Biological Transport|Calcium-Binding Proteins|Sequence Homology, Amino Acid 27 SLC25A24 25599384 J. Clin. Endocrinol. Metab. 2015 10.1210/jc.2014-2829 4 0 0 148 Mice|Humans|Animals|*Diet, Fat-Restricted|Adipocytes|Obesity|Adipogenesis|Adiposity|3T3-L1 Cells|Adipose Tissue|SLC25A24 protein, human|Calcium-Binding Proteins|Antiporters|Mitochondrial Proteins 27 SLC25A38 26637696 Hematology Am Soc Hematol Educ Program 2015 10.1182/asheducation-2015.1.19 5 0 0 20 Humans|Male|Animals|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Haem|Refractory Anemia|*RNA Splicing|Ribonucleoprotein, U2 Small Nuclear|Myelodysplastic Syndrome|Thrombocytosis|RNA Splicing Factors|Iron Overload|Bone Marrow|Erythroid Precursor Cells|Mutations|Phosphoproteins|Pyridoxin|Iron|Genetic Diseases, X-Linked|ALAS2 protein, human 35 SLC25A38 26636621 Syst Biol Reprod Med 2015 10.3109/19396368.2015.1100692 2 0 0 20 Pregnancy|Female|Humans|Infant|*Preimplantation Diagnosis|*beta-Thalassemia|*Anemia, Sideroblastic|*Histocompatibility Testing|*Genetic Testing|Fertilization in Vitro|Embryo Transfer|Histocompatibility|Prenatal Diagnosis|Siblings|Tandem Repeats, Short|Heterozygote|Hematopoietic Stem Cell Transplantation|*Immunologic Tests|Mutation|Haplotype|PCR, Multiplex|Slc25a38 protein, human 35 SLC31A2 26411550 Urol. Oncol. 2015 10.1016/j.urolonc.2015.08.013 2 0 0 125 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Nephrectomy|Prognosis|Nomograms|Neoplasm Recurrence, Local|Disease-Free Survival|Biomarkers, Tumor|Kaplan-Meier Estimate|Retrospective Studies|Immunoenzyme Techniques 28 SLC31A2 26342034 J. Immunol. 2015 PMC4592814 10.4049/jimmunol.1500283 7 13 0 125 *Tryptases|*Mast Cells|*Proteoglycans|Cation Transport Proteins|*Cell Differentiation|Copper|Secretory Granules|Biological Transport|Cytoplasmic Granules|*Cell Growth Processes|SLC31 Proteins 28 SLC31A2 26205368 Metallomics 2015 PMC4635045 10.1039/c5mt00131e 4 25 0 125 Animals|Female|Humans|SLC31A1 protein, human|*Copper Transporter 1|HEK293 Cells|Cisplatin|Cation Transport Proteins|Ovarian Cancer|Copper|SLC31 Proteins|Homeostasis|Plasma Membrane 28 SLC31A2 25750709 Biol Sex Differ 2015 PMC4352278 10.1186/s13293-015-0020-3 15 0 2 125 Humans|Female|Male|*Ethnic Groups|*Kidney|*Biological Transport|Membrane Transport Proteins|ATP-Binding Cassette Transporters|Liver|Gene Expression|Sex Differences|Real-Time Polymerase Chain Reaction 28 SLFN12 26656089 Nat. Chem. Biol. 2015 PMC4718766 10.1038/nchembio.1984 24 18 1 86 Phosphodiesterase 3A|*Anticancer Agents|3',5'-Cyclic-AMP Phosphodiesterases|*Cancer|Cyclic AMP 24 SLFN12 26623250 Results Immunol 2015 PMC4625362 10.1016/j.rinim.2015.10.001 17 14 1 86 Humans|Mice|Animals|*Monocytes|*T Cells|Lymphocyte Activation|Cell Differentiation|Cell Cycle Proteins|Signal Transduction|Interferon|Cell Line|Immunity, Innate|Upregulation|Dendritic Cells 24 SMPDL3B 26095358 Cell Rep 2015 PMC4508342 10.1016/j.celrep.2015.05.006 18 10 1 44 Mice|Animals|*Sphingomyelin Phosphodiesterase|*Immunity, Innate|Toll-Like Receptors|Macrophages|Signal Transduction|Ceramides|Peritonitis 23 SMPDL3B 25925039 Pediatr. Nephrol. 2015 PMC4689751 10.1007/s00467-015-3082-x 18 15 1 44 Nephrosis, congenital|*Nephrotic Syndrome|*Nephrosis, Lipoid|*Kidney Glomerulus|Podocyte|*Kidney Diseases|PLAUR protein, human|Plasminogen Activator Receptor, Urokinase Type|*Permeability|Signal Transduction|Proteins|Cytoskeleton 23 SPAG16 26706657 Eur. J. Neurol. 2015 10.1111/ene.12925 1 0 0 28 *Multiple Sclerosis|*Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Relapsing-Remitting|*Disease Progression|Autoantibodies|Recurrence|Enzyme-Linked Immunosorbent Assay|Disability Evaluation|*Antilymphocyte Serum 28 SPAG16 26634513 Genet. Mol. Res. 2015 10.4238/2015.November.30.25 6 6 1 28 Humans|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|Uric Acid|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Transcription Factor 7-Like 2 Protein|Genetic Predisposition to Disease|Genotype|Alleles|Gene Frequency|Blood Glucose|Metabolic Syndrome|Genes, p16|Insulin Resistance|Case-Control Studies|PON1 protein, human|Aryldialkylphosphatase|SLC2A9 protein, human 28 SPATA16 26516168 Mol. Hum. Reprod. 2015 10.1093/molehr/gav061 12 0 1 7 Humans|Male|*Teratozoospermia|Infertility, Male|Spermatozoa|Homozygote|Point Mutation|Gene Deletion|Alleles|Membrane Proteins|Cohort Studies|DPY19L2 protein, human 33 SPATA16 26178295 J. Obstet. Gynaecol. Res. 2015 10.1111/jog.12765 14 0 1 7 Humans|Male|*Infertility, Male|Azoospermia|Chromosomes, Human, Y|Spermatogenesis|Chromosome Deletion 33 SPATA16 25888788 Hum. Reprod. Update 2015 10.1093/humupd/dmv020 40 0 8 7 Male|Humans|*Teratozoospermia|AURKC protein, human|Aurora Kinase C|Infertility, Male|Sperm Tail|Spermatozoa|Mutations|Homozygote|Axonemes|Dynein|Spermatogenesis|Flagella|DPY19L2 protein, human|Membrane Proteins|DNAH1 protein, human 33 SPATA16 25711835 J. Assist. Reprod. Genet. 2015 PMC4380889 10.1007/s10815-015-0433-2 15 0 1 7 Male|Humans|*Teratozoospermia|DNA Fragmentation|Infertility, Male|Spermatozoa|Sperm Head|Intracytoplasmic Sperm Injection|In Situ Nick-End Labeling|Aneuploidy|Spermatogenesis|Mutations|Membrane Proteins|Flagella|Meiosis|DPY19L2 protein, human 33 SPOCK2 26471063 Semin. Perinatol. 2015 PMC4644695 10.1053/j.semperi.2015.09.004 13 1 2 42 Infant, Newborn|Infant|Humans|*Genetic Predisposition to Disease|*Bronchopulmonary Dysplasia|Genome-Wide Association Study|Pilot Projects|Polymorphism, Single Nucleotide|Infant, Premature|Infant, Very Low Birth Weight|Gestational Age|Genetic Variation|Cohort Studies|European Continental Ancestry Group 35 SPOCK2 26267680 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2015 10.11817/j.issn.1672-7347.2015.07.001 0 0 0 42 Humans|Female|*Cervix Uteri|*Squamous Carcinoma|Human papillomavirus 16|Papillomavirus Infections|Cervical Intraepithelial Neoplasia|Uterine Cervical Neoplasms|miRNAs|Gene Expression Regulation, Neoplastic|Down-Regulation|Biomarkers, Tumor|Up-Regulation 35 SPOCK2 26135768 J. Matern. Fetal. Neonatal. Med. 2015 10.3109/14767058.2015.1061495 5 0 2 42 Infant, Newborn|Humans|Infant|Animals|*Bronchopulmonary Dysplasia|*Neonatology|Metabolomics|*Biomarkers|Infant, Premature|Proteomics|Genomics|Gestational Age|MIRN152 microRNA, human|MicroRNAs 35 srpx 25620379 Mol. Carcinog. 2015 10.1002/mc.22258 5 4 2 33 Humans|Mice|Animals|lactate dehydrogenase 1|*L-Lactate Dehydrogenase|*Isoenzymes|Glycolysis|*Genes, Tumor Suppressor|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Downregulation|Adenocarcinoma|Cell Proliferation|Lactate|Glucose|Upregulation|mRNA|*Carbohydrate Metabolism|Transcriptional Activation 50 STK17B 26186199 Nat. Prod. Res. 2015 10.1080/14786419.2015.1046067 0 0 0 215 Humans|*Apocynaceae|Alkaloids, Monoterpenoid Indole|Drug Screening Assays, Antitumor|Molecular Structure|Antineoplastic Agents, Phytogenic|Cell Line, Tumor|HL-60 Cells|Crystallography, X-Ray|Magnetic Resonance Spectroscopy 32 STK40 26663584 Genes Cells 2015 10.1111/gtc.12323 23 3 4 141 *RNA, Micro|Epithelial-Mesenchymal Transition|*Endothelium|*Transforming Growth Factor|Transforming Growth Factor beta|Signal Transduction|Transforming Growth Factor beta1|Endothelial Cells|Phenotype 24 STK40 26286729 J. Natl. Cancer Inst. 2015 PMC4675101 10.1093/jnci/djv220 0 1 2 141 Humans|Rats|Animals|*Esophageal Neoplasms|Esophageal Squamous Cell Carcinoma|*Antagomirs|*Signal Transduction|Carcinoma, Squamous Cell|MicroRNAs|Gene Expression Regulation, Neoplastic|Esophagus|Cell Proliferation|Cell Line, Tumor|MIRN31 microRNA, human|MIRN31 microRNA, rat 24 STK40 26260799 Cardiovasc. Res. 2015 10.1093/cvr/cvv210 9 0 2 141 Humans|*Myocytes, Cardiac|*Heart Failure|AKT1 protein, human|*Protein Kinase B 24 STK40 26173551 Alcohol. Clin. Exp. Res. 2015 PMC5587504 10.1111/acer.12786 6 0 0 141 Humans|*Alcoholism|*Genome Wide Association Analysis|Genetic Predisposition to Disease|European Continental Ancestry Group|Polymorphism, Single Nucleotide|African Americans|Case-Control Studies|Membrane Proteins 24 STK40 26065429 J. Cell. Sci. 2015 10.1242/jcs.170282 8 7 0 141 Mice|Animals|*Adipogenesis|*CCAAT-Enhancer-Binding Proteins|3T3-L1 Cells|Adipocytes|CCAAT-Enhancer-Binding Protein-beta|Cell Differentiation|CCAAT-Enhancer-Binding Protein-alpha|CCAAT-Enhancer-Binding Protein-delta|PPAR gamma|EIF4EBP1 protein, human|Phosphoproteins|Mesenchymal Stem Cells|RNA, Small Interfering|Lipid Metabolism|Adaptor Proteins, Signal Transducing|Stk40 protein, mouse|Protein-Serine-Threonine Kinases 24 STK40 25568668 Genes Cancer 2015 PMC4279440 10.18632/genesandcancer.38 10 12 3 141 Humans|*Esophageal Neoplasms|MicroRNAs|Carcinoma, Squamous Cell|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Esophageal Squamous Cell Carcinoma|Real-Time Polymerase Chain Reaction|MIRN31 microRNA, human 24 STOML1 26444770 J. Alzheimers Dis. 2015 PMC4730943 10.3233/JAD-150335 16 4 0 71 *Alzheimer Disease|*Neuroimaging|Cognitive Impairment|Imaging, Magnetic Resonance|Brain|Apolipoproteins E|Parahippocampal Gyri|Temporal Lobe|Disease Progression|Hippocampus|ROC Curve|Biomarkers|Cohort Studies|Genotype 20 SWAP70 26544714 PLoS ONE 2015 PMC4636285 10.1371/journal.pone.0141927 6 12 2 162 Mice|Animals|interferon regulatory factor-4|*Interferon Regulatory Factors|*Lupus Erythematosus, Systemic|IL10 protein, human|IL10|*Lupus Erythematosus, Discoid|Cell Differentiation|Dendritic Cells|Autoimmunity|B Cells|Autoimmune Disease|DNA-Binding Proteins|Minor Histocompatibility Antigens|Spleen|Signal Transduction|Guanine Nucleotide Exchange Factors|Nuclear Proteins 81 SWAP70 26103139 Exp. 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Biol. 2015 10.1016/j.ydbio.2015.09.007 3 1 1 28 Humans|Animals|Chick Embryo|*Chicken|*Beak|*Face|Bone Morphogenetic Protein|BMP4 protein, human|Bone Morphogenetic Protein 4|Retinoic Acid|Transcription Factors|Morphogenesis|*Embryo, Mammalian|Cleft Lip|noggin protein|Carrier Proteins|Mesoderm|Homeodomain Proteins|Gene Expression Regulation, Developmental|Signal Transduction|FOXE1 protein, human 52 TBX22 26323392 BMC Med. Genet. 2015 PMC4593198 10.1186/s12881-015-0220-z 3 1 1 28 Male|Humans|*Cleft Palate|*Intellectual Disability|Cleft Lip|*Chromosome 1|Chromosome Deletion|Comparative Genomic Hybridization|Chromosomes, Human, X|Genes, X-Linked|*Hearing Impairment|Pedigree|*Disabled Persons|Growth Hormone 52 TBX22 25918826 Clin. Dysmorphol. 2015 10.1097/MCD.0000000000000088 1 0 1 28 Male|Humans|Female|Cleft palate X-linked|Cleft Palate|Cleft Lip|*Asian Continental Ancestry Group|Linkage Disequilibrium|Single Nucleotide Polymorphisms|Haplotypes|Alleles|Genetic Predisposition to Disease|Gene Frequency|Interferon Regulatory Factors|*Promoter Regions, Genetic|Genotype|Case-Control Studies|Genetic Diseases, X-Linked|TBX22 protein, human|T-Box Domain Proteins 52 TCF15 26428460 BMC Genet. 2015 PMC4591634 10.1186/s12863-015-0272-2 5 3 1 58 Humans|Mice|Animals|Endothelial Cells|Genetic Predisposition to Disease|Haplotypes|Polymorphism, Single Nucleotide|Coronary Artery Disease|Alleles|*Heart|Risk Factors|Case-Control Studies|*DNA Mutational Analysis|TCF15 protein, human|Basic Helix-Loop-Helix Transcription Factors|MEOX2 protein, human|Homeodomain Proteins|Meox2 protein, mouse 39 TCF15 26224636 J. Biol. Chem. 2015 PMC4566222 10.1074/jbc.M115.675595 17 4 2 58 *ets Transcription Factors|Glycogen Synthase Kinase 3|SMARCD3 protein, human|*Transcription Factors|*Embryonic Stem Cells|DNA-Binding Proteins|Cell Differentiation|Ectoderm|Cell Proliferation 39 TCF15 26010523 Dev. Dyn. 2015 10.1002/dvdy.24294 3 0 1 58 Mice|Animals|*Somites|*Xenopus laevis|*Morphogenesis|Mesoderm, Paraxial|*Cell Differentiation|Xenopus Proteins|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Embryonic Development|Cell Movement|Epithelial-Mesenchymal Transition 39 TCF15 25561514 Circulation 2015 10.1161/CIRCULATIONAHA.114.013721 18 3 1 58 *Endothelium, Vascular|Endothelial Cells|*Heart|*Fatty Acids|Myocardium|*Biological Transport|CD36 Antigens|Glucose|Fatty Acid-Binding Proteins 39 TDRD3 26099445 Reprod. Biomed. Online 2015 10.1016/j.rbmo.2015.05.001 5 0 0 132 Pregnancy|Humans|Female|*Ovarian Stimulation|Follicle Stimulating Hormone|Fertilization in Vitro|Sperm Injections, Intracytoplasmic|Receptors, FSH|Ovarian Follicles|Ovarian Reserve|Oocytes|Ovary|Genotypes|Phase, Follicular|*Reproduction|*Aging|*Biomarkers 25 TENM3 26485751 Horm Mol Biol Clin Investig 2015 10.1515/hmbci-2015-0032 2 0 0 39 Humans|Animals|teneurin-C terminal associated peptide|*Peptides|Amino Acid Sequence|Corticotropin Releasing Factor|Nerve Tissue Proteins|Tenascin|alpha-latrotoxin receptor|Receptors, Peptide|Peptide Fragments|*Reproduction|Exon 28 TENM3 26301688 Nat. Med. 2015 PMC4863040 10.1038/nm.3933 52 0 5 39 Humans|Child|Genome-Wide Association Study|Case-Control Studies|*Autoimmune Diseases|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Expression Regulation|Gene Regulatory Networks|IL2RA protein, human|Interleukin-2 Receptor alpha Subunit|Hypersensitivity 28 TEX14 26392564 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4603477 10.1073/pnas.1418606112 3 7 0 73 Male|Animals|*Testis|*Germ Cells|Cell Cycle Proteins|Cytokinesis|Transcription Factors|DNA-Binding Proteins|Spermatogenesis|Endosomal Sorting Complexes Required for Transport|Nuclear Proteins|Calcium-Binding Proteins|Protein Binding|Genes, cdc|*Gene Expression 43 TEX14 25791729 Asian J. Androl. 2015 PMC4430936 10.4103/1008-682X.148079 8 3 1 73 Humans|Male|Female|Pregnancy|Testicular Germ Cell Tumor|Genome-Wide Association Study|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Carcinoma in Situ|MAD1L1 protein, human|Nuclear Proteins|Cell Cycle Proteins|RFWD3 protein, human|Ubiquitin-Protein Ligases 43 TEX19 26695143 Tumour Biol. 2015 10.1007/s13277-015-4567-8 6 0 0 48 Humans|Male|*Urinary Bladder Neoplasms|*Testis|Carcinoma, Transitional Cell|RNA, Neoplasm|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|RNA, Messenger|Nuclear Proteins|Cell Line, Tumor|Tex19 protein, human 20 TEX19 26459560 BMC Evol. Biol. 2015 PMC4603632 10.1186/s12862-015-0506-y 1 9 1 48 Humans|Male|Pregnancy|Female|Mice|Animals|*Testis|*Phylogeny|*Eutherian|Germ Cells|RNA-Binding Proteins|Placenta|Nuclear Proteins|Amino Acid Sequence|Genome|SECTM1 protein, human|Membrane Proteins|Tex19 protein, human|Tex19 protein, mouse 20 TICRR 26710261 Nucleus 2015 PMC4915513 10.1080/19491034.2015.1115938 4 12 0 110 Humans|*Eukaryotic Cells|*DNA Replication|MCM2-7 Complex|Cell Cycle Proteins|Replication Origin|Saccharomyces cerevisiae Proteins|MCM2 protein, human|Minichromosome Maintenance Complex Component 2|Saccharomyces cerevisiae|DNA, Single-Stranded|DNA-Binding Proteins|DNA, Fungal|Phosphorylation|Protein-Serine-Threonine Kinases|S Phase|Cell Cycle|Protein Binding 29 TICRR 26405041 J. Biol. Chem. 2015 PMC4646389 10.1074/jbc.M115.688424 11 1 2 110 Humans|*S Phase|MCM5 protein, human|*Cell Cycle Proteins|DNA Replication|Minichromosome Maintenance Proteins|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Replication Origin|DNA, Single-Stranded|DNA-Binding Proteins|MCM2 protein, human|Minichromosome Maintenance Complex Component 2|DNA, Fungal|*Chromosome Structures|Phosphorylation|Sld3 protein, S cerevisiae 29 TICRR 26305950 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4568703 10.1073/pnas.1509608112 21 6 4 110 Humans|*Phosphorylation|MCM5 protein, human|Cell Cycle Proteins|DNA Replication|Saccharomyces cerevisiae|Minichromosome Maintenance Proteins|Saccharomyces cerevisiae Proteins|S Phase|DNA-Binding Proteins|Protein-Serine-Threonine Kinases|DNA, Single-Stranded|*Chromosome Structures|Protein Binding 29 TICRR 26238040 Mol Med Rep 2015 PMC4581807 10.3892/mmr.2015.4090 2 2 1 110 *Nasopharyngeal Carcinoma|*Network, Gene|*Carcinoma|Nasopharyngeal Neoplasms|Bioinformatics|Gene Ontology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|actin-binding protein anillin, human|Microfilament Proteins|Biomarkers, Tumor|centromere protein F|Chromosomal Proteins, Non-Histone|MicroRNAs|Protein Interaction Mapping|PDZ-binding kinase|Mitogen-Activated Protein Kinase Kinases|Cell Cycle 29 TICRR 25737283 Genes Dev. 2015 PMC4358407 10.1101/gad.246827.114 16 2 3 110 *S Phase|*Phosphorylation|*Cyclin-Dependent Kinases|DNA Replication|Cell Cycle Proteins|Saccharomyces cerevisiae Proteins|DNA-Binding Proteins|DNA Damage|Binding Protein|Nuclear Proteins|Cyclins 29 TICRR 25557548 Mol. Cell 2015 PMC4321788 10.1016/j.molcel.2014.12.003 33 44 3 110 Animals|*DNA Replication|CHEK1 protein, human|Chk1 Kinase|Cell Cycle Proteins|S Phase|Xenopus Proteins|DNA-Binding Proteins|Cyclin-Dependent Kinases|Phosphorylation|Replication Origins|Nuclear Proteins|Carrier Proteins|Xenopus laevis|Protein Kinases|Cell Cycle|DNA Helicases|Cyclin-Dependent Kinase 2|Chromatin 29 tiprl 26717153 PLoS ONE 2015 PMC4696667 10.1371/journal.pone.0145938 7 52 1 1859 protein phosphatase 4|*Phosphorylation|Cell Cycle Proteins|DNA Repair|Histones|DNA Damage|Protein Phosphatase 2|Ataxia Telangiectasia Mutated Proteins|Intracellular Signaling Peptides and Proteins|DNA-Binding Proteins|Tumor Suppressor Proteins 34 tiprl 25647515 Mol. Carcinog. 2015 10.1002/mc.22288 6 4 0 1859 *Taraxacum|Carcinoma, Hepatocellular|TNF Related Apoptosis Inducing Ligand|Liver Neoplasms|Apoptosis|JNK Mitogen-Activated Protein Kinases|Caspases|Antineoplastic Agents|Cell Line, Tumor|Drug Resistance, Neoplasm|*Cell Death 34 TLE6 26537248 Genome Biol. 2015 PMC4634911 10.1186/s13059-015-0792-0 26 9 1 17 Female|Humans|*Embryo, Mammalian|*Mutation|Oocytes|Embryonic Development|Genes, Lethal|Fertilization in Vitro|Infertility, Female|Phenotype|Tle6 protein, human|Transcription Factors 23 TM4SF5 26531872 Bratisl Lek Listy 2015 10.4149/bll_2015_118 4 0 0 210 *Stomach Neoplasms|lncRNA|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor|Oligonucleotide Array Sequence Analysis|mRNA 57 TM4SF5 26404468 Int Rev Cell Mol Biol 2015 10.1016/bs.ircmb.2015.06.004 5 1 0 210 *Epithelial-Mesenchymal Transition|Hepatic Cancers|Carcinoma, Hepatocellular|Hepatic Cells|Membrane Proteins|Liver|Cell Movement|Tetraspanin 24|EGFR protein, human|Epidermal Growth Factor Receptor|Cell Proliferation|Signal Transduction|CD44 protein, human|Hyaluronan Receptors|Integrins|Cell Line, Tumor|Fibrosis|Tumorigenesis 57 TM4SF5 26190015 Lung Cancer 2015 10.1016/j.lungcan.2015.06.023 5 22 0 210 IGF1R protein, human|*Receptors, Somatomedin|Carcinoma, Non-Small-Cell Lung|Erlotinib Hydrochloride|*Signal Transduction|ErbB Receptors|Gefitinib|Quinazolines|Protein Kinase Inhibitors|Lung Neoplasms|Drug Resistance, Neoplasm|Epithelial-Mesenchymal Transition|Antineoplastic Agents|Cell Line, Tumor|Insulin-Like Growth Factor I, Resistance To|*Growth Disorders|*Abnormalities, Multiple 57 TM4SF5 25772760 BMB Rep 2015 PMC4453026 10.5483/bmbrep.2015.48.3.047 3 9 1 210 Carcinoma, Hepatocellular|Liver Neoplasms|CD44 protein, human|*Hyaluronan Receptors|Signal Transduction|TWIST1 protein, human|Twist-Related Protein 1|Cell Movement|Membrane Proteins|Cell Line, Tumor|Circulating Tumor Cell|Phosphorylation|Liver|Nuclear Proteins 57 TM4SF5 25627085 Hepatology 2015 10.1002/hep.27721 16 6 0 210 Mice|Animals|Carcinoma, Hepatocellular|Liver Neoplasms|CD44 protein, human|*Hyaluronan Receptors|TWIST1 protein, human|Twist Related Protein 1|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|Epithelial-Mesenchymal Transition|TSPAN32 protein, human|*Tetraspanins|Signal Transduction|Cell Line, Tumor|Circulating Tumor Cell|BMI1 protein, human|Polycomb Repressive Complex 1|Membrane Proteins|Protein-Tyrosine Kinases 57 TMC8 26227733 Dermatology (Basel) 2015 10.1159/000435910 0 0 0 65 Humans|*Carcinoma, Squamous Cell|*Skin Neoplasms|*Kidney Transplantation|*Transplant Recipients|Epidermodysplasia Verruciformis|Papillomaviridae|Papillomavirus Infections|Single Nucleotide Polymorphisms|*Kidney|Genotype|Membrane Proteins|TMC8 protein, human 50 TMC8 25853559 PLoS ONE 2015 PMC4390289 10.1371/journal.pone.0123716 1 3 0 65 Humans|Female|*Papillomavirus Infections|*Head and Neck Cancer|Papillomaviridae|Squamous Cell Carcinoma|Head and Neck Squamous Cell Carcinoma|HPV 16|Genetic Susceptibility|Cervical Cancer|Genotype|Polymorphism, Single Nucleotide|Case-Control Studies|Mutations|TMC8 protein, human|Membrane Proteins 50 TMEFF1 26092120 Dis Model Mech 2015 PMC4527297 10.1242/dmm.021303 3 13 0 69 Mice|Animals|*MAP Kinase Signaling System|*Cardiac Hypertrophy|Myocardium|MAP Kinase Kinase Kinases|Ventricular Remodeling|Heart Failure|Mice, Transgenic|Myocytes, Cardiac|Signal Transduction|Echocardiography 26 TMEM135 25712083 Eur. J. Hum. Genet. 2015 PMC4592100 10.1038/ejhg.2015.3 4 0 1 40 Humans|*Multifactorial Inheritance|*Intelligence|Single Nucleotide Polymorphism|Genome-Wide Association Study|Quantitative Trait, Heritable|Quantitative Trait Loci|Phenotype|Genotype|Genome, Human|Genetic Testing|Longitudinal Studies 20 TMEM163 26601739 Neurobiol. Aging 2015 PMC4688052 10.1016/j.neurobiolaging.2015.09.014 31 0 1 9 *Parkinson Disease|Genome-Wide Association Study|alpha-Synuclein|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Disease Progression|Haplotypes|Age of Onset|Genotype|Case-Control Studies|tau Proteins|Mutations|Washington 22 TMEM163 26290879 J Diabetes Res 2015 PMC4531200 10.1155/2015/613236 6 1 1 9 Humans|Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Allele|Allele Frequency|KCNQ1 Potassium Channel|Genotype|Case-Control Studies|Ethnic Groups|Risk|European Continental Ancestry Group|Transcription Factors|China 22 TMEM38B 25565926 Mol Syndromol 2015 PMC4281578 10.1159/000369108 6 1 1 37 Humans|Osteogenesis imperfecta, type 6|*Osteogenesis Imperfecta|Brazil|Serpin Superfamily|Homozygote|Eye Proteins|Nerve Growth Factors|Mutations|Collagen Type I|*Genes, Regulator|Bone|FKBP10 protein, human|Tacrolimus Binding Proteins 25 TMEM70 26675066 BBA Clin 2015 PMC4633944 10.1016/j.bbacli.2014.09.003 3 5 0 63 Child|Humans|*Disorders, Mitochondrial|Oxidative Phosphorylation|Cell Respiration|Electron Transport|Mitochondria|Electron Transport Complex IV|Mitochondrial Proteins|Oxygen Consumption|*Lymphocytes|Fibroblasts 44 TMEM70 26550569 Biomed Res Int 2015 PMC4621340 10.1155/2015/462592 1 3 1 63 Humans|Child|*Mitochondria|Mitochondrial ATP Synthase|Mitochondrial Proteins|*Mutation|3-Methylglutaconic Aciduria|*Metabolism, Inborn Errors|Oxidative Phosphorylation|Mitochondrial Membranes|Membrane Proteins|Homozygote|Cardiomyopathy|Adenosine Triphosphate|TMEM70 protein, human 44 TMEM70 26214044 Ultrastruct Pathol 2015 10.3109/01913123.2015.1054013 0 0 0 63 Humans|*Disorders, Mitochondrial|*Mitochondria|Mitochondrial Proteins|Mitochondrial Membranes|Transmission Electron Microscopy|*Myoblasts|Fluorescence Microscopy|Fiji 44 TMEM70 25825456 Europace 2015 10.1093/europace/euv043 5 0 0 63 Humans|*KCNQ1 Potassium Channel|*Cardiomyopathy, Hypertrophic|Cardiac Myosins|*Phenotypes|*Heterozygote|Cardiomyopathy, Hypertrophic, Familial|*Mutations|Myosin Heavy Chains|*Chinese|Pedigree|Genotype|Exons|Genetic Predisposition to Disease|Echocardiography|Mutation, Missense|Electrocardiography|KCNQ1 protein, human|MYH7 protein, human 44 TNP2 26714726 J. Mol. Histol. 2015 10.1007/s10735-015-9647-y 3 0 0 42 Male|Rats|Humans|Animals|*Busulfan|*Testis|*Rats, Wistar|Spermatogenesis|Seminiferous Tubules|Spermatogonia|Sperm|Sertoli Cells|*Granulocyte Colony-Stimulating Factor|*Testicular Diseases|Azoospermia|Antineoplastic Agents, Alkylating|Fertility|Proliferating Cell Nuclear Antigen|Organ Size|Ddx4 protein, rat|DEAD-box RNA Helicases 118 TNP2 26268249 Mol. Hum. Reprod. 2015 10.1093/molehr/gav046 0 1 0 42 Male|Humans|Mice|Animals|protamine P2|*Protamines|protamine 2|Tnp2 protein, mouse|*Nuclear Proteins|Sperm|Spermatogenesis|Histones|Testis|Spermatids|Epididymis|Chromatin|immunoglobulin B|*Immunoglobulins|Cell Nucleus|Epitopes 118 TONSL 26527279 Mol. Cell 2015 PMC4656108 10.1016/j.molcel.2015.08.005 27 62 4 109 Humans|Animals|*Histones|*Molecular Chaperones|Histone Chaperones|Chromatin|DNA Replication|Cell Cycle Proteins|Protein Binding|MCM2-7 Helicase|Models, Molecular|TONSL protein, human|NF-kappa B|MMS22L protein, human|DNA-Binding Proteins|Nuclear Proteins 28 TONSL 25644976 Am. J. Chin. Med. 2015 10.1142/S0192415X1550007X 4 2 2 109 ICAM1 protein, human|*Intercellular Adhesion Molecule-1|epigallocatechin gallate|*Monocytes|*Green Tea|*Catechin|NF-kappa B|Signal Transduction|*Polyphenols|Cell Adhesion|Tumor Necrosis Factor-alpha|Retinal Pigment Epithelium|Cytokines|Cells, Cultured|Reactive Oxygen Species|Cell Movement|Epithelial Cells|Retinal Pigments 28 tppp3 25576359 Biochem. Biophys. Res. Commun. 2015 10.1016/j.bbrc.2014.12.099 5 0 1 109 Animals|Humans|*Zebrafish|*Tubulin|*Polymerization|Zebrafish Proteins|Amino Acid Sequence|Evolution, Molecular|Conserved Sequence|Synteny|Phylogeny|Genome|Sequence Homology, Amino Acid|Nerve Tissue Proteins 22 TRAK2 26658612 Mol. Biol. Cell 2015 PMC4751598 10.1091/mbc.E15-09-0632 14 28 2 105 *Mitochondria|Mitochondrial Proteins|*Adenomatous Polyposis Coli|Microtubules|rho GTP-Binding Proteins|Kinesin|Biological Transport|Protein Transport|*Plasma Membrane 46 TRAK2 26553875 J. Biol. Chem. 2015 PMC4705382 10.1074/jbc.M115.699447 31 26 3 105 *Mitochondrial Dynamics|*Neurons|Mitochondrial Proteins|Mitochondria|Axons|Nerve Tissue Proteins|Mitochondrial Membrane, Outer|Protein Transport|Schizophrenia|Endoplasmic Reticulum|Biological Transport|Cells, Cultured|*Morphogenesis|Dendrites 46 TSHZ1 26621817 Sci Rep 2015 PMC4664893 10.1038/srep17369 11 6 1 48 Humans|Female|*Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Endometrial Cancer|Colorectal Cancer|Alleles|LNK protein, human|*Proteins|Odds Ratio|Case-Control Studies|Genotype|European Continental Ancestry Group|Risk Factors|TSHZ1 protein, human|Homeodomain Proteins 42 TSHZ1 26561393 Hum. Genet. 2015 PMC4698300 10.1007/s00439-015-1606-x 8 5 1 48 Humans|Animals|Mice|*Cleft Lip|*Cleft Palate|*DNA Copy Number Variations|Genome-Wide Association Study|Genetic Predisposition to Disease|Phenotype|Polymorphism, Single Nucleotide|*Cohort Studies|Genomics|Genes, Regulator|Transcription Factors|Genes, Homeobox|SATB2 protein, human|Matrix Attachment Region Binding Proteins 42 TSHZ1 25918232 Diabetes 2015 PMC4512227 10.2337/db14-1443 8 12 0 48 Humans|Mice|Animals|Diabetes Mellitus, Type 2|pancreatic and duodenal homeobox 1 protein|Homeodomain Proteins|Trans-Activators|*Cell Differentiation|*Pancreas|Insulin-Secreting Cells|Transcription Factor|Organogenesis|Insulin|Endocrine Pancreas|Stem Cells|Endocrine Cells|Insulin Secretion|Gene Expression Regulation, Developmental|Chromatin Immunoprecipitation|CLEC16A protein, human|Monosaccharide Transport Proteins 42 TSHZ1 25628336 Hum. Mol. Genet. 2015 PMC4383869 10.1093/hmg/ddv028 16 2 2 48 Humans|Male|Female|Genome-Wide Association Study|*Motion Sickness|Nausea|Vomiting|Vestibule, Labyrinth|Single Nucleotide Polymorphisms|Vertigo|Altitude Sickness|Phenotypes|*Homeostasis|Glucose|HoxB3 protein, human|Homeodomain Proteins 42 TSPY1 26511781 Sex Transm Infect 2015 PMC6801014 10.1136/sextrans-2015-052072 17 0 1 100 Humans|Female|*Vaginosis, Bacterial|*HIV Infections|Cross-Sectional Studies|*STI|*Cytokines|Vagina|*Biomarkers|Inflammation|Cervix Uteri|Asymptomatic Infections 125 TSPY1 26420680 Anim. Sci. J. 2015 10.1111/asj.12523 0 0 0 100 Pregnancy|Humans|Male|Female|Animals|*Macaca fascicularis|*DNA Copy Number Variations|*Fetus|Sex Determination Analysis|*DNA|sry Gene|Prenatal Diagnosis|*Prenatal Care|Maternal-Fetal Exchange|*Number, Gene Copy|Chromosomes, Human, Y|Real-Time Polymerase Chain Reaction|Plasma|*Diagnostic Tests, Routine 125 TTC12 26410615 Pharmacol. Biochem. Behav. 2015 PMC4635661 10.1016/j.pbb.2015.09.018 3 1 0 11 Humans|*African Americans|*Dopamine|*Smoking|Dependence, Nicotine|European Continental Ancestry Group|*Motivation|*Tobacco Smoking|Haplotypes|Receptors, Dopamine D2|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Craving|Phenotype|Neural Cell Adhesion Molecules|Wisconsin|TTC12 protein, human|Proteins 24 TTC12 25989041 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2015 10.1002/ajmg.b.32317 0 0 0 11 Adult|Humans|*Attention Deficit Disorder with Hyperactivity|Depressive Disorder, Major|DRD2 protein, human|*Receptors, Dopamine D2|Haplotypes|*Gene Cluster|*Neural Cell Adhesion Molecules|Linkage Disequilibrium|Genetic Predisposition to Disease|Gene Frequency|Phenotypes|Polymorphism, Single Nucleotide|Genotype|Genetic Variation|CD56 Antigen|Protein-Serine-Threonine Kinases|TTC12 protein, human|Proteins 24 TWSG1 26517884 Biochem. Soc. Trans. 2015 PMC4613500 10.1042/BST20150071 5 16 2 895 Animals|chordin|*Bone Morphogenetic Protein|*Growth Factors|*Glycoproteins|Tolloid Metalloproteases|Body Patterning|Signal Transduction|Protein Binding|Zebrafish|Xenopus Proteins|Drosophila Proteins|von Willebrand Factor 47 TWSG1 25910190 PLoS ONE 2015 PMC4409381 10.1371/journal.pone.0124217 2 8 1 895 Humans|Rats|Animals|*Factor, Angiogenic|*Osteogenesis|Bone Morphogenetic Proteins|Fracture Healing|*Signal Transduction|Bone Morphogenetic Protein 2|BMP4 protein, human|Bone Morphogenetic Protein 4|BAMBI protein, human|Membrane Proteins|Closed Fracture|*Atrophy|*Hypertrophy 47 TWSG1 25808976 J. Cell. Biochem. 2015 PMC4853233 10.1002/jcb.25174 4 18 0 895 *Osteoclasts|*Gastrulation|*Signal Transduction|Bone Morphogenetic Proteins|*Protein Binding|Bone Morphogenetic Protein 2|Osteoclastogenesis|*Hematopoiesis|Gene Expression Regulation 47 TWSG1 25710710 Curr. Opin. Hematol. 2015 PMC4509743 10.1097/MOH.0000000000000132 40 30 5 895 Animals|*Erythropoiesis|*Iron|Hepcidins|Iron Overload|beta-Thalassemia|Homeostasis|Disease Models, Animal 47 TWSG1 25592806 Trends Cell Biol. 2015 10.1016/j.tcb.2014.12.004 81 2 12 895 Humans|Animals|chordin|Glycoproteins|Intercellular Signaling Peptides and Proteins|Bone Morphogenetic Proteins|noggin protein|Carrier Proteins|*Signal Transduction|Protein Binding|*Gene Expression Regulation 47 txnl1 26605532 Nature 2015 PMC4697938 10.1038/nature15740 90 2 9 480 Humans|Animals|*DNase I|Chromatin|Regulatory Sequences, Nucleic Acid|Chromosome Mapping|Genome, Plant|Promoter Regions, Genetic|Gene Expression|TXNL1 protein, human|Thioredoxins 37 txnl1 26401249 Pulm Circ 2015 PMC4556499 10.1086/682219 5 0 0 480 Humans|*Heart Ventricles|*Heart Failure|Echocardiography|TYRP1 protein, human|*Membrane Glycoproteins|Proteomics|Gene Expression Regulation|HSPB2 protein, human|HSP27 Heat-Shock Proteins|TXNL1 protein, human|Thioredoxins 37 txnl1 25561728 J. 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Med. 2015 PMC4564085 10.3892/ijmm.2015.2323 6 6 1 157 Humans|*RNA, Small Interfering|*Down-Regulation|*Cell Proliferation|*Glioma|*Cell Cycle|Gene Knockdown Techniques|RNA Interference|Cell Line, Tumor|Carrier Proteins|Glioblastoma|Ubiquitins|Ubap2L protein, human 21 ULK4 26208877 Autophagy 2015 PMC4590660 10.1080/15548627.2015.1067362 34 20 3 17 Humans|KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|NF-E2-Related Factor 2|*Autophagy|Clustering|Databases, Genetic|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|mRNA|Genes, Regulator|Non-Small-Cell Lung Carcinomas|Clear Cell Renal Carcinoma|Tumorigenesis|Genes, cdc|Mutation|Cancer, Kidney 27 ULK4 25637795 Neuroscience 2015 10.1016/j.neuroscience.2014.12.060 5 0 1 17 Animals|*Xenopus laevis|*Neurogenesis|Neural Stem Cells|Prosencephalon|Neurons|Transcription Factors|Tyrosine Hydroxylase|Gene Expression Regulation, Developmental|Microtubule-Associated Proteins|Immunohistochemistry|Cell Movement|In Situ Hybridization|Ependymoglial Cells|Lipid-Binding Protein, Brain|Protein-Serine-Threonine Kinases|Serine 27 UPK1A 25701463 Med. Oncol. 2015 10.1007/s12032-015-0541-y 0 4 0 118 Animals|*Carcinoma, Transitional Cell|*Uroplakin 1a|*Down-Regulation|*Urinary Bladder|*Urinary Bladder Neoplasms|*Apoptosis|Cell Proliferation|Proto-Oncogene Proteins c-bcl-2|Cell Line, Tumor|Urothelium|Gene Expression Regulation, Neoplastic|Flow Cytometry 66 URAD 25746298 Environ. Res. 2015 10.1016/j.envres.2014.10.028 2 0 0 3 Child|Female|Humans|*Pilot Projects|*Biological Monitoring|*Feasibility Studies|phthalic acid|Phthalic Acids|Mercury|Environmental Pollutants|Environmental Exposure|Cotinine|Environmental Monitoring|Cadmium|Hair|bisphenol A|Benzhydryl Compounds|Environmental Health|Phenols|Biomarkers|Mothers 55 USP29 26427096 Yakushigaku Zasshi 2015 0 0 0 22 Dogs|Animals|potassium bromide|*Bromides|Japan|*Potassium Compounds|*Psychotropic Drugs|Valerian|Hypnotics and Sedatives|*Health Services|*Research Design|Mental Disorders|Medicine|Knowledge|Maintenance|Organizations|Regrets|Internationality|Cephapirin 34 VAX2 26068435 BMC Med. Genet. 2015 PMC4630852 10.1186/s12881-015-0182-1 2 3 0 24 *Acidosis, Renal Tubular|Anion Exchange Protein 1, Erythrocyte|Hearing Loss, Sensorineural|Vacuolar Proton-Translocating ATPases|Mutations|Exons|*Genomics|Phenotype 164 VAX2 25886149 Neural Dev 2015 PMC4373414 10.1186/s13064-015-0035-9 4 14 0 24 Animals|Hedgehog Proteins|*Xenopus laevis|*Signal Transduction|Body Patterning|*Retina|Gene Expression Regulation, Developmental|Trans-Activators|Homeodomain Proteins|Transcription Factors|T-Box Domain Proteins|Eye Proteins 164 VIPAS39 26463206 J. Biol. Chem. 2015 PMC4683254 10.1074/jbc.M115.688440 21 0 4 57 Animals|*Endosome|rab7 protein|rab GTPases|Vesicular Transport Proteins|Lysosomes|SNARE Proteins|Vacuoles|Saccharomyces cerevisiae|Protein Transport|Arthrogryposis renal dysfunction cholestasis syndrome|Arthrogryposis|Protein Binding|Cholestasis|Renal Insufficiency|*Mammals 24 WDFY4 26663301 2015 PMC4981330 10.1002/art.39548 15 4 1 12 Humans|Genome-Wide Association Study|Republic of Korea|*Lupus Erythematosus, Systemic|Genetic Susceptibility|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|STAT4 Transcription Factor|Tumor Necrosis Factor alpha-Induced Protein 3|Case-Control Studies|DNA-Binding Proteins|Odds Ratio|FCHSD2 protein, human|Carrier Proteins|Membrane Proteins|P2RY2 protein, human|Receptors, Purinergic P2Y2 20 WDFY4 26089329 Stroke 2015 PMC4740911 10.1161/STROKEAHA.115.009044 17 0 3 12 Humans|*Genome-Wide Association Study|*African Americans|*Risk Factors|*Stroke|Brain Ischemia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies 20 WDFY4 25860243 Leuk. Lymphoma 2015 10.3109/10428194.2015.1028051 8 0 0 12 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*miRNA|Prospective Studies|*Receptors, Antigen, B-Cell|*Subset, B-Cell|Immunoglobulin Variable Region|Immunoglobulin Heavy Chains|Complementarity Determining Regions|Gene Expression Regulation, Leukemic|Prognosis|Mutations|MIRN497 microRNA, human 20 WHAMM 26675239 J. Cell. Sci. 2015 10.1242/jcs.179325 4 2 1 1784 Animals|*Drosophila|*Actins|WAS protein, human|Wiskott-Aldrich Syndrome Protein|Drosophila Proteins|Drosophila melanogaster|Microfilament Proteins|Arp2-3 Complex|*Morphogenesis|*Cell Motility|Myoblasts|Cell Fusion|*Organogenesis|Endocytosis|*Macrophage|Whamy protein, Drosophila 33 WHAMM 26643602 Sci Rep 2015 PMC4672326 10.1038/srep17882 3 1 1 1784 Humans|*Genetic Predisposition to Disease|*Chronic Periodontitis|Haplotype|Linkage Disequilibrium|Genotype|Polymorphism, Single Nucleotide|Gene Frequency|Asian Continental Ancestry Group|Case-Control Studies|AP3B2 protein, human|Adaptor Protein Complex 3|Adaptor Protein Complex beta Subunits|WHAMM protein, human|Membrane Proteins|Microtubule-Associated Proteins 33 WHAMM 26305109 Nucleus 2015 PMC4915506 10.1080/19491034.2015.1086051 5 31 1 1784 Animals|*Wiskott-Aldrich Syndrome|WAS protein, human|*Wiskott-Aldrich Syndrome Protein|Arp2-3 Complex|*Cell Nucleus|Actin|Wiskott-Aldrich Syndrome Protein, Neuronal|Drosophila Proteins|Microfilament Proteins|Drosophila|Cytoskeleton|Vesicular Transport Proteins|Cell Movement|Microtubules|Whamy protein, Drosophila 33 WHAMM 26291929 Autophagy 2015 PMC4590594 10.1080/15548627.2015.1073434 5 2 1 1784 *Arp2-3 Complex|*Actins|Autophagosomes|*Autophagy|Microtubule-Associated Proteins|Endoplasmic Reticulum|Membrane Proteins 33 WHAMM 26096974 Curr. Biol. 2015 PMC4489997 10.1016/j.cub.2015.05.042 33 12 5 1784 *Arp2-3 Complex|*Actins|*Autophagosomes|Microtubules|Golgi Apparatus|Microtubule-Associated Proteins|Membrane Proteins|Autophagy|Cell Motility 33 WHAMM 26057447 PLoS Genet. 2015 PMC4461293 10.1371/journal.pgen.1005248 11 12 2 1784 Humans|Dogs|Animals|*Lupus Erythematosus, Systemic|Antinuclear Antibodies|*Phenotypes|Haplotypes|Autoimmune Disease|*Genomics|Alleles|Genetic Predisposition to Disease|*Gene Expression|Disease, Canine|Case-Control Studies|VRK1 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|LAMTOR3 protein, human|Adaptor Proteins, Signal Transducing 33 WHAMM 25746724 Exp. Cell Res. 2015 10.1016/j.yexcr.2015.02.023 7 4 2 1784 Chlorocebus aethiops|Animals|*Golgi Apparatus|*Protein Transport|*Plasma Membrane|Endoplasmic Reticulum|Transport Vesicles|Endosome|rho GTPases|Actin|Membrane Proteins|COS Cells|Cell Movement|*Biological Transport|G Protein 33 XIRP2 26656454 J Am Heart Assoc 2015 PMC4845292 10.1161/JAHA.115.002443 8 3 1 38 Child|Humans|Female|Adult|*Cardiomyopathy, Dilated|*Exome|*Whole Exome Sequencing|*Mutations|Pedigree|Troponin T 42 XIRP2 26252659 PLoS ONE 2015 PMC4529093 10.1371/journal.pone.0134146 3 5 1 38 Swine|Animals|*Tetralogy of Fallot|*Myocardium|Heart Ventricles|Arrythmia|Ventricular Remodeling|Heart|Endocardium|Gene Expression Profiling|*Gene Expression|Disease Models, Animal 42 XIRP2 26126603 J. Periodont. Res. 2015 10.1111/jre.12303 7 0 0 38 Mice|Animals|*Alveolar Bone Loss|*Multifactorial Inheritance|*Quantitative Trait Loci|*Periodontitis|*Inflammation|Porphyromonas gingivalis|*Biofilm|Dysbiosis|*Psychomotor Disorders|Host-Pathogen Interactions|Disease Models, Animal|*Perceptual Disorders 42 XPO4 26671762 Sci Rep 2015 PMC4680864 10.1038/srep17985 10 4 1 139 *Proteome|Glycogen Synthase Kinase 3|Pluripotent Stem Cells|Embryonic Stem Cells|Cell Differentiation|mESCs|SMARCA4 protein, human|Transcription Factors|Cell Proliferation|Cell Cycle|SMARCC1 protein, human|Cell Adhesion|Cells, Cultured|Proteomics|Focal Adhesion|Mitogen-Activated Protein Kinases|DNA Helicases|Nuclear Proteins 35 XPO4 26354774 Toxicol. Sci. 2015 PMC5009438 10.1093/toxsci/kfv191 0 2 0 139 Mice|Animals|Epithelial-Mesenchymal Transition|arsenite|*Arsenites|*Zinc|SMAD2 protein, human|Smad2 Protein|*Cell Differentiation|Smad Proteins|Transforming Growth Factor beta2|Smad3 Protein|Signal Transduction|*Organogenesis|Phosphorylation|Epithelial Cells|Cell Movement|Lens, Crystalline|Mesenchymal Stem Cells|Cell Line 35 XPO4 26293807 Sci Rep 2015 PMC4543956 10.1038/srep13306 1 1 1 139 Humans|*Non-alcoholic Fatty Liver Disease|*DNA Copy Number Variations|Liver|Case-Control Studies|Cohort Studies|Biomarkers|Triglycerides|Biopsy|Karyopherins|Xpo4 protein, human 35 XPO4 25911113 Mol. Cell. Endocrinol. 2015 PMC4458229 10.1016/j.mce.2015.04.014 6 17 0 139 Humans|*Exportins|*Thyroid Hormone Receptor|Nuclear Import|Cytoplasm|Cell Nucleus|calreticulin, human|Calreticulin|Protein Transport|Green Fluorescent Proteins|HeLa Cells|RNA Interference|Nuclear Export Signals 35 ZC3H12D 26470939 Anal. Biochem. 2015 10.1016/j.ab.2015.10.002 2 1 0 498 *DNA Methylation|*Semen|hydrogen sulfite|Sulfites|Forensic Genetics|CpG Islands|Epigenetic|*Body Fluids|Saliva|*Bodily Secretions|Sequence Analysis, DNA|DNA|Genetic Markers|Real Time Polymerase Chain Reaction|*Stains 20 ZC3H12D 26134560 J. Biol. Chem. 2015 PMC4543641 10.1074/jbc.M114.635870 0 3 0 498 Animals|*Interleukin-6|*mRNA Degradation|Ribonucleases|Transcription Factors|TYRP1 protein, human|*Membrane Glycoproteins|3' Untranslated Regions|RNA, Messenger|Inflammation|Amino Acid Sequence|*Synapsins|Co-Immunoprecipitation|Monocyte Chemoattractant Proteins 20 ZC3H12D 26059755 Mol. Immunol. 2015 10.1016/j.molimm.2015.05.018 0 13 0 498 Mice|Animals|*Inflammation|*mRNA Stability|Lipopolysaccharides|Acute Lung Injury|NF-kappa B|Signal Transduction|Proto-Oncogene Proteins c-fos|Cytokines|Tumor Necrosis Factor-alpha|Lung|3' Untranslated Region 20 ZC3H14 25980665 Dev Neurobiol 2015 PMC4644733 10.1002/dneu.22301 12 6 2 116 Animals|Humans|*Drosophila|Drosophila melanogaster|ZC3H14 protein, human|*RNA Binding Protein|*Axons|*Neurons|Drosophila Proteins|Nuclear Proteins|Mushroom Bodies|RNA, Messenger|Memory|Conserved Sequence|Courtship|Brain|Hippocampus|Intellectual Disability 23 ZDHHC9 26493349 Clin. Exp. Med. 2015 10.1007/s10238-015-0393-y 1 0 0 61 Humans|*Multiple Myeloma|Prognosis|Bone Marrow|Gene Expression Regulation, Neoplastic|Lactate Dehydrogenase|Progression-Free Survival|Bone Disease|Upregulation|Biomarkers|mRNA 30 ZDHHC9 26358559 Am. J. Med. Genet. A 2015 10.1002/ajmg.a.37378 3 0 0 61 Male|Humans|Lujan Fryns syndrome|Mental Retardation, X-Linked|Craniofacial Abnormalities|Marfan Syndrome|Genes, X-Linked|Intellectual Disability|Phenotypes|Mediator Complex|Telomeric 22q13 Monosomy Syndrome|Chromosome Disorders|Mutation|Pedigree|Whole Exome Sequencing|Chromosome Deletion|Chromosomes, Human, Pair 22|ZDHHC9 protein, human|Acyltransferases 30 ZDHHC9 26000327 Ann Clin Transl Neurol 2015 PMC4435709 10.1002/acn3.196 5 0 1 61 Humans|Male|*Neuroanatomy|*Epilepsy|*Cognition Disorders|*Mutations|Phenotypes|*Cognitive Dysfunction|Intellectual Disability|Brain|Neurodevelopmental Disorders|Cognition|ZDHHC9 protein, human|Acyltransferases 30 ZDHHC9 25649377 Eur. J. Hum. Genet. 2015 PMC4613482 10.1038/ejhg.2015.5 35 0 3 61 Humans|Male|Female|*Intellectual Disability|*Genes, X-Linked|*Sequencing, Next-Generation|Pedigree|X Chromosome Inactivation|Mutation|Transcription Factors|KDM5C protein, human|Histone Demethylases|Cohort Studies|SLC9A6 protein, human|Sodium-Hydrogen Exchangers|ZDHHC9 protein, human|Acyltransferases|IQSEC2 protein, human|Guanine Nucleotide Exchange Factors 30 zfhx4 26643480 J. Immunol. 2015 PMC4707113 10.4049/jimmunol.1501708 6 32 0 66 Humans|Mice|Animals|*Drosophila|*RNA Interference|*Hypercapnia|Drosophila Proteins|Drosophila melanogaster|Innate Immune Response|*Immunologic Factors|Antimicrobial Cationic Peptides|Carbon Dioxide|Staphylococcal Infections|Zfhx3 protein, mouse|Homeodomain Proteins|Zfh2 protein, Drosophila|DNA-Binding Proteins 26 zfhx4 25855136 Nat Commun 2015 PMC4403348 10.1038/ncomms7825 20 6 4 66 Humans|Genome-Wide Association Study|Carcinoma, Basal Cell|SNPs|Genetic Predisposition to Disease|Skin Neoplasms|CASP8 protein, human|Caspase 8|Alleles|Case-Control Studies|Genotype|European Continental Ancestry Group|GATA3 protein, human|GATA3 Transcription Factor|Intron|*B-Lymphocytes|Iceland 26 ZNF185 26377798 Am. J. Physiol. Renal Physiol. 2015 10.1152/ajprenal.00525.2014 1 0 0 64 Animals|*Zebrafish|Zebrafish Proteins|Podocytes|*Proteinuria|Kidney Glomerulus|Glomerular Filtration Barrier|Morpholinos|Gene Knockdown Techniques|Larvae|Tmem234 protein, zebrafish|Membrane Proteins 24 ZNF365 26677210 Cancer Epidemiol. Biomarkers Prev. 2015 10.1158/1055-9965.EPI-15-0746 1 0 0 33 Humans|Female|*Breast Density|Genome-Wide Association Study|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Genotype|Case-Control Studies|Risk Factor 57 ZNF365 26628628 Br J Ophthalmol 2015 10.1136/bjophthalmol-2015-307366 1 0 0 33 Humans|*Uveomeningoencephalitic Syndrome|Genome-Wide Association Study|Thailand|beta-apocarotenoid-14',13'-dioxygenase|*Asian Continental Ancestry Group|IL23R protein, human|*Receptors, Interleukin|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Behcet Syndrome|Case-Control Studies|ZNF365 protein, human|DNA-Binding Proteins|Transcription Factors|EGR2 protein, human|Early Growth Response Protein 2 57 ZNF365 26287344 Zhongguo Dang Dai Er Ke Za Zhi 2015 0 0 0 33 Child|Humans|Single Nucleotide Polymorphisms|*Asthma, Bronchial|Genetic Predisposition to Disease|Gene Frequency|Asian Continental Ancestry Group|Genotype|Immunoglobulin E|Case-Control Studies|China|ZNF365 protein, human|DNA-Binding Proteins|Transcription Factors 57 ZNF365 26275715 Breast Cancer Res. 2015 PMC4537547 10.1186/s13058-015-0625-9 5 0 1 33 Humans|Female|*Breast Density|*Hormone Replacement Therapy|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Postmenopause|Case-Control Studies 57 ZNF365 26073781 Am. J. Hum. Genet. 2015 PMC4572510 10.1016/j.ajhg.2015.05.002 15 2 3 33 Humans|Genome-Wide Association Study|SNPs|Genetic Predisposition to Disease|Asian|*Risk|Haplotype|Chromosome Mapping|Promoter Regions, Genetic|Quantitative Trait Loci|Alleles|European Continental Ancestry Group|Case-Control Studies|Genotype|Enhancer Elements, Genetic|NRBF2 protein, human|Trans-Activators 57 ZNF365 26036842 Breast Cancer Res. 2015 PMC4501298 10.1186/s13058-015-0591-2 10 4 2 33 Humans|Female|*Breast Density|Mammography|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Study, Genetic Association|Genotype|Phenotype|DNA Mutational Analysis|Risk Factors 57 ZNF365 25870223 Cancer Epidemiol. Biomarkers Prev. 2015 10.1158/1055-9965.EPI-14-1362 0 0 0 33 *Pectoralis Muscles|*Digital Mammography|Density, Mammographic|Early Detection of Cancer|Case-Control Studies|Risk Factors|*Biomarkers 57 ZNF365 25862352 Cancer Res. 2015 PMC4470785 10.1158/0008-5472.CAN-14-2012 23 4 5 33 Female|Humans|*Breast Density|Mammography|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Risk Factors|Linear Models|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 57 ZNF365 25705664 Biomed Res Int 2015 PMC4332974 10.1155/2015/492367 20 41 2 33 *Depressive Disorder, Major|*Oligodendrocytes|*Schizophrenia|DNA-Binding Proteins|Transcription Factors|Nerve Tissue Proteins|Cell Differentiation|Neurogenesis|Corticosterone 57 ZNF365 25595671 Anat Sci Int 2015 10.1007/s12565-014-0269-3 6 1 1 33 *Depression|*Schizophrenia|zinc-binding protein|Carrier Proteins|Nerve Tissue Proteins|DNA-Binding Proteins|Transcription Factors|kendrin|Calmodulin-Binding Proteins|Neurons|Neurogenesis|Oligodendrocytes|Pituitary Adenylate Cyclase-Activating Polypeptide|Polymorphism, Single Nucleotide|Depressive Disorder, Major|Adaptor Proteins, Signal Transducing|Protein Binding|Cell Differentiation 57 ZNF644 26365379 Mol. Cell 2015 PMC4575883 10.1016/j.molcel.2015.07.030 105 32 8 140 Humans|DNA Replication|DNA Repair|DNA Damage|Cell Cycle Proteins|Chromatin|Ataxia Telangiectasia Mutated Proteins|DNA|ZNF644 protein, human|Transcription Factors 20 ZNF644 25880754 Arthritis Res. Ther. 2015 PMC4392874 10.1186/s13075-015-0590-9 11 12 3 140 Humans|*Wnt Signaling Pathway|*Case-Control Studies|*CD4-Positive T-Lymphocytes|*Rheumatoid Arthritis|STAT3 protein, human|*STAT3 Transcription Factor|*Transcriptome Analysis|Interleukin-6|Transcriptome 20 ZNF644 25789554 Elife 2015 PMC4365668 10.7554/eLife.05606 15 31 1 140 Histone H3|Histone-Lysine N-Methyltransferase|*Gene Expression|Chromatin|Histocompatibility Antigens|DNA Methylation|Transcription Factors|Protein Processing, Post-Translational|Protein Binding|Zinc Finger Motifs 20 ZNF91 25917792 Chin J Integr Med 2015 10.1007/s11655-015-1970-3 0 2 0 55 panaxadiol|*Saponins|*Megakaryocytes|*Transcriptome|*Ginsenosides|*Cell Differentiation|Panax ginseng|Hematopoiesis|Bone Marrow Cells|Cell Proliferation|Cells, Cultured|*Cell Count|Up-Regulation|*Microarray Analysis|*Nonprescription Drugs 26 ZPBP2 26671913 J. Med. Genet. 2015 10.1136/jmedgenet-2015-103313 3 2 0 22 *DNA Methylation|*Founder Effect|*Asthma|*Genotype|Promoter Regions, Genetic|Gene Expression Regulation|Genome-Wide Association Study|Phenotype|Membrane Proteins|Polymorphism, Single Nucleotide|Egg Proteins|Genetic Variation|Neoplasm Proteins 39 ZPBP2 26485223 Viral Immunol. 2015 10.1089/vim.2015.0067 5 0 0 22 Child|Humans|Infant|Child, Preschool|*Diabetes Mellitus, Type 1|*Enterovirus Infections|Enterovirus|HLA-DQ8 antigen|HLA-DQ Antigens|Genotype|HLA-DRB1 Chains|Single Nucleotide Polymorphisms|*Complement Factor B|Genetic Predisposition to Disease|Interferon-Induced Helicase, IFIH1|RNA, Viral|DEAD-box RNA Helicases|Feces|Immunity, Innate|Norway|C1qTNF6 protein, human|Collagen 39 ZPBP2 26484354 Biomed Res Int 2015 PMC4592899 10.1155/2015/834805 6 3 1 22 Humans|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn's Disease|*Genotype|Colon|Intestinal Mucosa|Genetic Predisposition to Disease|Gene Frequency|Ileum|Polymorphism, Single Nucleotide|Inflammation|Biopsy|Proteins|GSDMA protein, human|Neoplasm Proteins|MIEN1 protein, human|Intracellular Signaling Peptides and Proteins|GSDMB protein, human 39 ZPBP2 26483175 J. 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Res. 2014 PMC4258122 10.1161/CIRCRESAHA.115.304216 11 24 2 65 Endothelial Cells|*Cell Differentiation|Cardiomyocytes|Regeneration|Stem Cells|Mesenchymal Stem Cells|Stem Cell Transplantation|Cell Proliferation|Myocardial Infarction|Ventricular Function, Left|Cells, Cultured|Neovascularization, Physiologic|Stroke Volume|*Multipotent Stem Cells 27 ABI3BP 24442417 Hum. Genet. 2014 10.1007/s00439-014-1418-4 10 0 3 65 Adult|Humans|*Kashin-Beck Disease|*DNA Copy Number Variations|Asian Continental Ancestry Group|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|*Research Design 27 ACAP2 24600047 Mol. Biol. Cell 2014 PMC4004601 10.1091/mbc.E13-10-0600 15 42 1 127 ADP-ribosylation factor 6|*ADP-Ribosylation Factors|cytohesin-2|GTPase Activating Protein|rab GTP-Binding Proteins|*Neurogenesis|Sheaths, Myelin|Guanine Nucleotide Exchange Factor|Signal Transduction|Oligodendrocyte|Axons|Cell Differentiation|Neurons|Cells, Cultured|Downregulation 26 ACOD1 25216059 Oncol. Rep. 2014 10.3892/or.2014.3474 3 11 0 3025 Animals|Mice|Epigenesis, Genetic|*Glioma|Cell Proliferation|*Oncogene|Brain Neoplasms|CCND1 protein, human|Cyclin D1|RNA Interference|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|CDH1 protein, human|E Cadherin|Mice, Nude|STAT3 protein, human|STAT3 Transcription Factor|Signal Transduction|RNA, Small Interfering 24 ACRV1 25158006 Mol. Reprod. 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Treat. 2014 10.1007/s10549-014-3041-4 11 0 1 13 Humans|Female|Genome-Wide Association Study|ERBB2 protein, human|Receptor, ErbB-2|*Chinese|Single Nucleotide Polymorphisms|Receptors, Estrogen|Receptors, Progesterone|Genetic Predisposition to Disease|Genotype|Case-Control Studies|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 31 ADAM29 24732660 Biomed J 2014 10.4103/2319-4170.113188 1 0 0 13 Humans|*Transcriptome|*Leukocytes, Mononuclear|*Sleep Apnea, Obstructive|Polysomnography|*Asian|*Leukocytes 31 ADAM29 24670651 Nature 2014 10.1038/nature13176 293 0 39 13 Humans|*Esophageal Squamous Cell Carcinoma|Comparative Genomic Hybridization|Esophageal Cancer|*Genomics|Carcinoma, Squamous Cell|Mutation|Exome|KMT2D protein, human|Neoplasm Proteins|DNA Copy Number Variations|Genetic Predisposition to Disease|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Esophagus|Sequence Analysis, DNA|Cell Cycle|Phenotypes|Genes, p16 31 ADAM29 24475022 PLoS ONE 2014 PMC3903472 10.1371/journal.pone.0082185 15 12 3 13 Humans|Iran|Microsatellite Instability|*Tumors, Colorectal|MutL Protein Homolog 1|DNA Methylation|Microsatellite Repeats|Nuclear Proteins|Adaptor Proteins, Signal Transducing|African Americans 31 ADAM7 25519703 BMC Cancer 2014 PMC4301544 10.1186/1471-2407-14-977 7 3 1 20 Humans|Male|*Prostate Cancer|*Prognosis|Androgen Antagonists|*Prostate|*Transcriptome Analysis|Prostatectomy|*Biopsy|Docetaxel|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Transcriptome|Oncogene Proteins, Fusion|Cell Line, Tumor 24 AFAP1L2 24995146 Scientifica (Cairo) 2014 PMC4068053 10.1155/2014/903014 7 43 3 160 Humans|Mice|Animals|*Adaptor Proteins, Signal Transducing|*Tumorigenesis|Cell Proliferation|Signal Transduction|Proto-Oncogene Proteins c-akt|*Cell Transformation, Neoplastic|Cell Cycle|Cell Survival|Phosphorylation|Apoptosis|Cell Line, Tumor|Tyrosine Kinase|RNA, Small Interfering|RNAi|Downregulation|Gastric Cancers|XB130 protein, mouse|Microfilament Proteins 30 AFAP1L2 24581082 World J Surg Oncol 2014 PMC3996025 10.1186/1477-7819-12-49 4 2 0 160 *Prognosis|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Pancreas|Adenocarcinoma|Neoplasm Staging|Lymphatic Metastasis|Biomarkers, Tumor|Neoplasm Invasiveness|Cell Proliferation|Survival Rate|Cell Migration|Immunoenzyme Techniques|Adaptor Proteins, Signal Transducing 30 AFAP1L2 24387290 J Transl Med 2014 PMC3882781 10.1186/1479-5876-12-1 6 24 18 160 Mice|Animals|*Stomach Neoplasms|Neoplasm Invasiveness|Cell Movement|Proto-Oncogene Proteins c-akt|Epithelial-Mesenchymal Transition|Phosphatidylinositol 3-Kinases|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Stomach|Signal Transduction|Cadherins|Vimentin|Cell Line, Tumor|Mice, Nude|RNA Interference|Prognosis|Transcription Factors|XB130 protein, mouse 30 AMIGO2 25244943 Brain Struct Funct 2014 10.1007/s00429-014-0891-9 23 0 3 92 Mice|Animals|*Habenula|*Transcriptome|*Neurons|*Transcriptome Analysis 28 ANKRD17 24612202 J. Intern. Med. 2014 PMC4130802 10.1111/joim.12215 12 6 3 122 Humans|*Hydrochlorothiazide|*Antihypertensive Agents|*Pharmacogenetics|*Hyperuricemia|Hypertension|Diuretics, Thiazide|Atenolol|Blood Pressure|Single Nucleotide Polymorphisms|European Continental Ancestry Group|Genome-Wide Association Study|African Americans|Blood Glucose 24 ANKRD17 24589211 Chin J Cancer 2014 PMC4059866 10.5732/cjc.013.10136 5 5 1 122 Humans|Female|*Cisplatin|*RNA, Micro|*mRNA|*Ovarian Cancer|*Carcinoma, Ovarian Epithelial|Drug Resistance, Neoplasm|Downregulation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Up-Regulation|Apoptosis|Signal Transduction|*Ovary 24 ANP32E 25225945 High Alt. Med. Biol. 2014 PMC4273201 10.1089/ham.2014.1036 12 0 1 183 Humans|*Altitude Sickness|Altitude|Polycythemia|Hypoxia|Phenotype|Linkage Disequilibrium|*Chronic Disease|Sequencing, Whole Genome|Genetic Variation|Peru|SENP1 protein, human|Cysteine Endopeptidases 36 ANP32E 25156960 Bioessays 2014 PMC4270211 10.1002/bies.201400058 21 12 2 183 Animals|ANP32A protein, human|Intracellular Signaling Peptides and Proteins|Nuclear Proteins|Nerve Tissue Proteins|Amino Acid Sequence 36 ANP32E 24613878 Cell Res. 2014 PMC3975505 10.1038/cr.2014.30 33 9 3 183 Animals|*Histones|Nucleosomes|Chromatin|Chromatin Assembly and Disassembly|Saccharomyces cerevisiae|Molecular Chaperones|Saccharomyces cerevisiae Proteins|DNA|Protein Binding|Crystallography, X-Ray|Amino Acid Sequence|Transcription Factors|Models, Molecular|Histone Chaperones 36 ANP32E 24463511 Nature 2014 10.1038/nature12922 75 2 8 183 Humans|Animals|*Chromatin|*Histones|Nucleosome|ANP32E protein, human|Nuclear Proteins|Molecular Chaperones|EP400 protein, human|DNA-Binding Proteins|Phosphoproteins|Saccharomyces cerevisiae Proteins|DNA Helicases|Saccharomyces cerevisiae|Protein Binding|Chromatin Immunoprecipitation|Amino Acid Sequence|Cell Nucleus|Histone Chaperones 36 AOAH 25351125 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2014 0 0 0 51 Humans|*Polymorphism, Single Nucleotide|*Sinusitis|Rhinitis|Nasal Polyps|*Chinese|Gene Frequency|Genetic Predisposition to Disease|*Chronic Disease|Genotype 51 AP3M2 24923803 Genetics 2014 PMC4125407 10.1534/genetics.114.166165 0 1 1 40 Mice|Animals|*Quantitative Trait Loci|Chromosome Mapping|Genomics|SNPs|Phenotype 25 APOBEC3D 25411794 PLoS Genet. 2014 PMC4238949 10.1371/journal.pgen.1004761 48 4 7 83 Humans|*HIV-1|vif Gene Products, Human Immunodeficiency Virus|Cytosine Deaminase|vif Gene|APOBEC-3G Deaminase|HIV Infections|vif Protein|*Mutation|Virus Replication|Cytidine Deaminase|*Polymorphism, Genetic|Aminohydrolases|Haplotypes|CD4-Positive T-Lymphocytes|DNA, Viral|*HIV Seropositivity|vif protein, Human immunodeficiency virus 1|APOBEC3G protein, human 32 APOBEC3D 25330146 PLoS Pathog. 2014 PMC4199767 10.1371/journal.ppat.1004453 38 8 9 83 Mice|Animals|*HIV-1|vif Gene Products, Human Immunodeficiency Virus|Cytosine Deaminase|APOBEC-3G Deaminase|Cytidine Deaminase|Virus Replication|RNA, Viral|*HIV Seropositivity|Mutations|Cell Line|*Disease Models, Animal|Apobec3 protein, mouse 32 APOBEC3D 25296601 Tumori 2014 10.1700/1636.17922 5 0 1 83 Humans|Male|*Cytosine Deaminase|*Mutations|*Prostate Cancers|Cytidine Deaminase|*Stomach|Gene Expression Regulation, Neoplastic|Minor Histocompatibility Antigens|Immunohistochemistry|Stomach Neoplasms|DNA|Colorectal Neoplasms|APOBEC3B protein, human|APOBEC3 protein, human 32 APOBEC3D 25080100 PLoS Pathog. 2014 PMC4117599 10.1371/journal.ppat.1004281 37 1 5 83 Humans|*Human Immunodeficiency Virus Type 1|APOBEC3 protein, human|Cytosine Deaminase|vif Gene Products, Human Immunodeficiency Virus|APOBEC-3G Deaminase|Cytidine Deaminase|HIV Infections|Virus Replication|Mutations|Aminohydrolases|DNA Sequencing|Mutagenesis|APOBEC3G protein, human 32 ATL2 24939275 J Contemp Dent Pract 2014 10.5005/jp-journals-10024-1497 0 0 0 95 *Dental Occlusion|*Complete Dentures|*Ear Auricle|Denture Design|Jaw Relation Record|Cephalometry|Nose|*Orientation, Spatial|Anatomic Landmarks 23 ATRN 25318887 J. Huazhong Univ. Sci. Technol. Med. Sci. 2014 10.1007/s11596-014-1346-5 0 0 0 64 Male|Mice|Humans|Animals|Child|*BALB C Mice|*Genitalia, Male|Testis|Epididymis|Sperm|ATRN protein, human|*Membrane Proteins|Semen|Azoospermia|Semen Analysis|In Situ Hybridization|mRNA|Gene Expression Regulation, Developmental 82 ATRN 25306804 Zhonghua Nan Ke Xue 2014 0 1 0 64 Male|Mice|Animals|*Sertoli Cells|*Antioxidants|*Apoptosis|Superoxide Dismutase|Oxidative Stress|ATRN protein, human|Membrane Proteins|Cell Line 82 ATRN 24533825 Clin Proteomics 2014 PMC3942106 10.1186/1559-0275-11-6 35 2 4 64 Humans|*Synovial Fluid|*Proteomics|Proteome|Cartilage, Articular|Osteoarthritis, Knee|Biomarkers|Mass Spectrometry|Glycoproteins 82 ATRNL1 25470129 PLoS ONE 2014 PMC4254279 10.1371/journal.pone.0112566 12 42 4 17 Humans|Mice|Animals|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|*Osteoblasts|*Cell Differentiation|TGFB1 protein, human|*Transforming Growth Factor beta1|*Osteogenesis|3T3 Cells|Transforming Growth Factor beta|Osteocalcin|Signal Transduction|IGF1 protein, human|Insulin-Like Growth Factor I|Periodontal Ligament|Alkaline Phosphatase|Cell Line|Gene Expression 30 ATRNL1 25187572 Mol. Cell Proteomics 2014 PMC4256491 10.1074/mcp.M114.040691 11 5 0 17 *Osteogenesis|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|*Mesenchymal Stem Cells|*Acetylglucosamine|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|BMP2 protein, human|Osteoblasts|Cell Differentiation|Bone Marrow Cells|Transforming Growth Factor beta|Calcification, Physiologic|Osteocalcin|Alkaline Phosphatase|Cells, Cultured|UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase|N-Acetylglucosaminyltransferases 30 BARHL2 25281935 Dev. Biol. 2014 10.1016/j.ydbio.2014.09.027 7 0 2 57 *Hedgehog Proteins|*Genes, Homeobox|*Prosencephalon|Body Patterning|Homeodomain Proteins|*Signal Transduction|Thalamus|Embryonic Induction|Embryonic Development|Diencephalon|Gene Expression Regulation, Developmental|Transcription Factors|Trans-Activators 30 BARHL2 24715462 Development 2014 10.1242/dev.099002 6 3 1 57 Mice|Animals|MSX2 protein|Homeodomain Proteins|NEUROG1 protein, human|Basic Helix-Loop-Helix Transcription Factors|*Spinal Cord|Transcription Factors|Cell Differentiation|LIM-Homeodomain Proteins|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Bone Morphogenetic Proteins|Interneurons|Signal Transduction|Wnt Proteins|Neurons|Cell Lineage|Organogenesis|Atoh1 protein, mouse 30 BLID 24532431 Tumour Biol. 2014 10.1007/s13277-014-1710-x 1 0 0 49 Humans|Ductal Carcinoma In Situ|Carcinoma, Ductal, Breast|Hyperplasia|*Disease Progression|*Neoplastic Processes|DNA, Neoplasm|Biomarkers, Tumor|Precancerous Conditions|Antineoplastic Agents|*Breast Neoplasms|BLID protein, human|Apoptosis Regulatory Proteins 187 BMP2K 24455749 J Diabetes Res 2014 PMC3888709 10.1155/2013/970435 14 19 2 204 Humans|*Diabetes Mellitus, Type 2|*Obesity|*Gene Expression Profiling|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|*Microarray Analysis|BAP1 protein, human|Tumor Suppressor Proteins|Ubiquitin Thiolesterase|BCAT1 protein, human|Transaminases|SLC35B4 protein, human|Nucleotide Transport Proteins|POC1B protein, human|Cell Cycle Proteins|MYNN protein, human|Kruppel-Like Transcription Factors 23 BRAC1 25366782 Genet. Mol. Res. 2014 10.4238/2014.October.31.6 0 0 1 0 Humans|Male|Female|Adult|Middle Aged|Aged|Aged, 80 and over|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|ErbB Receptors|TTF1 protein, human|DNA-Binding Proteins|NKX2-1 protein, human|Thyroid Nuclear Factor 1|*Oncogene|Endonucleases|Mutation|Transcription Factors|ras Proteins|Prognosis|Drug Resistance, Neoplasm|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Gene Expression Regulation, Neoplastic|Tubulin 40 BRAC1 25327411 ACS Nano 2014 10.1021/nn504983j 5 0 1 0 Humans|*Silver|*Quantum Dots|*Nucleic Acids|DNA|Nanostructure|Nucleic Acid Hybridization|Luminescence 40 BRAC1 25313729 J Cancer Res Ther 2014 10.4103/0973-1482.137927 59 0 11 0 Humans|Female|MUC1 protein, human|Mucin-1|CEACAM5 protein, human|Carcinoembryonic Antigen|Prognosis|Biomarkers, Tumor|Urokinase-Type Plasminogen Activator|Cathepsin D|GPI-Linked Proteins|Asia 40 BRSK1 25036402 Exp. Mol. Pathol. 2014 10.1016/j.yexmp.2014.07.012 3 10 1 135 Humans|*Prognosis|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|EPHA5 protein, human|*Brain-Specific Kinase|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|COP9 Signalosome Complex|*Cytoplasm|Intracellular Signaling Peptides and Proteins|Signal Transduction|*Cytosol|Cell Line, Tumor|*Mammary Carcinoma, Human|BRSK1 protein, human|Protein-Serine-Threonine Kinases 48 BRSK1 24759943 PLoS ONE 2014 PMC3997365 10.1371/journal.pone.0095194 6 23 1 135 Mice|Animals|*Insulin-Secreting Cells|*Proteomics|Pancreatic alpha Cells|Insulin|Glucagon|Cell Transdifferentiation|Proteome|Cell Line|Signal Transduction|Phosphorylation 48 BRSK1 24493794 Hum. Mol. Genet. 2014 PMC4030781 10.1093/hmg/ddu041 17 0 0 135 Female|Humans|*African Americans|*Menopause|Genome-Wide Association Study|Menarche|Genetic Loci|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Genotype|Phenotype|Age Factors|Reproduction 48 BRSK1 24395778 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC3903204 10.1073/pnas.1321990111 10 0 1 135 Mice|Animals|Synapses|Axons|Presynaptic Terminals|Neuromuscular Junction|Motor Neurons|*Systems, Central Nervous|Protein-Serine-Threonine Kinases|Spinal Cord|Neurogenesis|Sensory Neurons 48 BRWD3 24462886 Eur J Med Genet 2014 10.1016/j.ejmg.2013.12.012 7 0 2 50 Male|Humans|Young Adult|Adult|*Intellectual Disability|*Macrocephaly|*Mutation|Exome|Mutation, Nonsense|Pedigree|Transcription Factors|BRWD3 protein, human 25 BRWD3 24374353 Genetics 2014 PMC3948805 10.1534/genetics.113.159707 11 3 3 50 Animals|*Drosophila|Drosophila melanogaster|Ecdysone|Metamorphosis, Biological|Drosophila Proteins|Pupa|Larvae|20 Hydroxyecdysone|Genes, Insect|Transcription Factors|Transcription, Genetic|Gene Expression Regulation, Developmental|Signal Transduction|Salivary Glands|RNA, Messenger|Pak protein, Drosophila|p21-Activated Kinases 25 BRWD3 24372385 Epilepsia 2014 10.1111/epi.12502 17 0 1 50 Humans|Child|*Epilepsy, Rolandic|DNA Copy Number Variations|*Genomics|Comparative Genomic Hybridization|*Genes, Regulator|PRRT2 protein, human|Membrane Proteins|Nerve Tissue Proteins 25 BTG4 24686393 Epigenetics 2014 PMC4053441 10.4161/epi.28603 13 2 1 17 *Leukemia, Lymphocytic, Chronic, B-Cell|RNA, Micro|DNA Methylation|5 Azacytidine|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Decitabine|Epigenetic|Promoter Regions, Genetic|trichostatin A|Hydroxamic Acids|Cell Line, Tumor|Apoptosis|Chromosomes|Cohort Studies 40 C2CD4B 25135348 Pharmacogenomics J. 2014 PMC6512969 10.1038/tpj.2014.41 3 1 1 16 *Insulin|*Glucose|*Potassium|*Insulin, Regular, Human|Syndromes, Acute Coronary|Cardioplegic Solutions|Myocardial Infarction|Myocardium|Electrocardiography|Emergency Care|*Phenotype|Infusions, Intravenous|Double-Blind Method|Heart Arrest|Treatment Outcome|Genetic Variation 24 C5orf42 25407461 Hum. Genet. 2014 PMC4282684 10.1007/s00439-014-1508-3 9 0 4 15 Humans|Orofaciodigital syndrome 6|*Orofaciodigital Syndromes|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|Cerebellar Diseases|Cerebellum|Phenotype|Retina|Mutations|Polydactyly|Hypothalamic hamartomas|Hypothalamic Diseases|Hamartoma|Membrane Proteins|C5orf42 protein, human 24 CARD6 24777975 Hypertension 2014 10.1161/HYPERTENSIONAHA.113.03021 9 3 0 74 Mice|Rats|Animals|*Caspase Activation and Recruitment Domain|*Cardiac Hypertrophy|Cardiomyocytes|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Ventricular Remodeling|Mice, Knockout|Mice, Transgenic|Signal Transduction|Heart Failure|Angiotensin II|*Protective Agents 30 CARD6 24402574 Tumour Biol. 2014 10.1007/s13277-013-1569-2 4 1 0 74 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Neoplasm Recurrence, Local|*Chemoradiotherapy|Carcinoma, Squamous Cell|Salvage Therapy|Prognosis|Treatment Outcome|Retrospective Studies|*Apoptosis|BCLAF1 protein, human|Repressor Proteins|Tumor Suppressor Proteins 30 CCDC170 25370037 Eur. J. Hum. Genet. 2014 PMC4463506 10.1038/ejhg.2014.219 12 0 1 50 Humans|Genome-Wide Association Study|Neoplasm Recurrence, Local|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Estrogen Receptor alpha|Linkage Disequilibrium|Genotypes|Alleles|Case-Control Studies|*Disease Progression|Prognosis|Phenotype|Gene Expression|RMND1 protein, human|Cell Cycle Proteins 22 CCDC170 25116933 Breast Cancer Res. 2014 PMC4303231 10.1186/s13058-014-0422-x 9 2 2 50 Humans|Genome-Wide Association Study|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Estrogen Receptor alpha|Case-Control Studies|Genotype 22 CDC42EP4 25086031 J. Biol. Chem. 2014 PMC4162185 10.1074/jbc.M114.577783 3 8 1 127 Humans|*Protein Kinase C|*Phosphorylation|Tandem Mass Spectrometry|*Cell Motility|Signal Transduction|Filopodia|Guanine Nucleotide Exchange Factor|Cell Line, Tumor 20 CDC42EP4 25022875 Mol. Cell Proteomics 2014 PMC4223502 10.1074/mcp.O114.038588 17 0 2 127 Humans|Proteomics|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|Phosphopeptides|Phosphorylation|Phosphoproteins|Mass Spectrometry|Substrate Specificity|Signal Transduction|Amino Acid Sequence|*Isotopes 20 CDH16 25223521 Mol. Cancer Res. 2014 10.1158/1541-7786.MCR-14-0022 6 0 1 53 FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|*Oncogenes|Bladder Cancer|Mutation|*Tumorigenesis|Bladder|*Cell-Matrix Junctions|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Phosphorylation|*Epithelial Cells|Cell Adhesion 48 CDH19 25466287 BMC Cancer 2014 PMC4265448 10.1186/1471-2407-14-902 6 0 2 36 Humans|*Alleles|CYP2C19 protein, human|*Cytochrome P-450 CYP2C19|*Triple-Negative Breast Cancer|DNA Copy Number Variations|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Case-Control Studies|Gene Duplication|DAB2IP protein, human|ras GTPase-Activating Proteins 25 CDH19 25361488 J. Neurosurg. 2014 PMC4337891 10.3171/2014.9.JNS132373 5 6 0 36 *Glioblastoma|*Myelin Sheath|Brain Neoplasms|Neoplastic Stem Cells|DCHS1 protein, human|*Cadherins|Neural Stem Cells|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Proliferation|Gene Expression Profiling|*B Cells|Tissue Array Analysis 25 CDH22 25101798 Genes Immun. 2014 PMC4257866 10.1038/gene.2014.47 8 2 1 30 Child|Humans|United States|*Mucocutaneous Lymph Node Syndrome|*Immunoglobulins, Intravenous|*Genotype|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genome-Wide Association Study|*European Continental Ancestry Group|Asian Continental Ancestry Group|Coronary Artery Disease|3' Untranslated Region|Case-Control Studies|*Administration, Intravenous|Genes, MHC Class II|Intergenic Region|BAZ1A protein, human|Transcription Factors 26 CDKL2 25333262 Oncotarget 2014 PMC4279414 10.18632/oncotarget.2535 11 31 2 100 Humans|*Epithelial-Mesenchymal Transition|Zinc Finger E-box-Binding Homeobox 1|Cadherins|Homeodomain Proteins|MCF-7 Cells|*Disease Progression|Transcription Factors|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|Cell Line, Tumor|Cell Proliferation|Cell Movement|mRNA|*Neoplastic Processes 20 CDKL2 25089541 Epigenetics 2014 PMC4164500 10.4161/epi.29632 18 4 1 100 *DNA Methylation|*B-DNA|Receptor, ErbB-2|CpG Islands|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Promoter Regions, Genetic|Cell Line, Tumor 20 CDY1 25143276 Yi Chuan 2014 10.3724/SP.J.1005.2014.0786 1 0 0 6 Male|Humans|*Alleles|*Infertility, Male|Azoospermia|Chromosomes, Human, Y|Oligospermia|*Men|Sequence Tagged Site|Seminal Plasma Proteins|Chromosome Deletion|Short Tandem Repeat|Genetic Loci|Sertoli Cell-Only Syndrome 54 CDY1 25042452 Gene 2014 10.1016/j.gene.2014.07.042 5 0 0 6 Humans|Male|*Risk Factors|*Infertility, Male|Deleted in Azoospermia 1 Protein|Azoospermia|Oligospermia|*Y-Chromosome Gene|Chromosomes, Human, Y|Spermatogenesis|Gene Deletions|RNA-Binding Proteins|Fertility|Nuclear Proteins|Case-Control Studies|CDY1 protein, human 54 CDY1 24727632 Stem Cell Res 2014 10.1016/j.scr.2014.03.002 10 0 4 6 *Cellular Reprogramming|Induced Pluripotent Stem Cells|Cell Differentiation|Embryo, Mammalian|Fibroblasts|Gene Expression Profiling|Cells, Cultured|Cell Proliferation 54 CDY1 24552450 Acc. Chem. Res. 2014 10.1021/ar400285f 13 1 0 6 *Fluorescence|glutathione green|Boron Compounds|Fluorescent Probes|Fluorescence Microscopy|Combinatorial Chemistry Techniques|Embryonic Stem Cells|*Cell Differentiation|Neural Stem Cells|Fatty Acid-Binding Protein 7|Staining and Labeling|Small Molecule Libraries|Induced Pluripotent Stem Cells|Neurons 54 CECR2 25064398 Fertil. Steril. 2014 PMC4184939 10.1016/j.fertnstert.2014.06.028 10 5 1 63 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Discoidin Domain Receptor 1|*DNA Methylation|*B-DNA|Spermatogenesis|CpG Islands|Testis|Promoter Regions, Genetic|Spermatozoa|Fertility|Phenotype|Genetic Predisposition to Disease 32 CELF4 24372884 Int J Lang Commun Disord 2014 10.1111/1460-6984.12047 4 0 0 34 Child|Humans|Adolescent|*Comprehension|Language Therapy|*Communication Disorders|Speech Therapy|Language Development Disorders|Language Tests|Treatment Outcome 43 CEND1 25173157 Methods Mol. Biol. 2014 10.1007/978-1-4939-1435-7_2 2 0 0 30 Animals|*Neural Stem Cell|*Stem Cell Transplantation|*Hematopoietic Stem Cell Transplantation|*Disease Models, Animal|*Traumatic Brain Injury|Neurons|Cell Differentiation|Cells, Glial|Brain Injuries|Spinal Cord Injuries|Central Nervous System 26 CEND1 25163507 BMC Genomics 2014 PMC4153944 10.1186/1471-2164-15-716 20 3 4 30 Pregnancy|Humans|Female|Infant, Newborn|Swine|Animals|*Methylation|Preterm Infants|*Intestine|Enterocolitis, Necrotizing|Animals, Newborn|Intestinal Microbiota|Intestinal Mucosa|Colostrum|Sus scrofa|Infant Formula|Premature Birth|*Parturition|Microbiota|Food, Formulated 26 CEND1 24526440 Invest. Ophthalmol. Vis. Sci. 2014 10.1167/iovs.13-12986 1 0 0 30 Animals|*Optic Nerve Injuries|*Down-Regulation|Nerve Crush|Retinal Ganglion Cells|Nerve, Optic|Cell Survival|Disease Models, Animal 26 CES1P1 24535487 Pharmacogenet. Genomics 2014 10.1097/FPC.0000000000000035 13 2 2 5 Humans|CYP2C19 protein, human|*Cytochrome P-450 CYP2C19|*Clopidogrel|Ticlopidine|Platelet Aggregation Inhibitors|*Coronary Heart Disease|Platelet Aggregation|Aryl Hydrocarbon Hydroxylases|*Chinese|Aryldialkylphosphatase|Genotype|Polymorphism, Single Nucleotide 20 CES1P1 24512105 Alcohol. Clin. Exp. Res. 2014 PMC3999255 10.1111/acer.12364 2 0 0 5 Humans|Female|United States|Male|*African Americans|*DNA Copy Number Variations|*Alcoholism|*Ethnic Groups|*European Continental Ancestry Group|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Genome|DNA Sequence 20 CFDP1 25547403 Chromosoma 2014 10.1007/s00412-014-0503-8 5 0 1 43 Animals|Cattle|*Chromatin|*Chromosome|Drosophila Proteins|Drosophila|Phosphoproteins|Amino Acid Sequence|Evolution, Molecular|Sequence Alignment|Phylogeny|Yeti protein, Drosophila|Carrier Proteins 40 CFDP1 25093840 PLoS ONE 2014 PMC4122436 10.1371/journal.pone.0104082 16 4 2 43 Humans|*Coronary Artery Disease|Carotid Intima-Media Thickness|Case-Control Studies|*Atherosclerosis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|*Complement Factor B|Risk Factors|Allele|Odds Ratio 40 CFDP1 24652835 J. Cell. Sci. 2014 10.1242/jcs.150243 8 2 1 43 Animals|*Drosophila melanogaster|Drosophila Proteins|Polytene Chromosomes|Chromatin|Histone H2a|Drosophila|Transcription Factors|Chromatin Assembly and Disassembly|*Gene, Essential|ATPase|Protein Binding|Tip60 protein, Drosophila|Histone Acetyltransferases|Yeti protein, Drosophila|Carrier Proteins|dom protein, Drosophila 40 CFDP1 24397353 Clin. Exp. Immunol. 2014 PMC3992034 10.1111/cei.12268 12 24 0 43 Humans|*Synovial Membranes|*Rheumatoid Arthritis|Osteoarthritis|Ankylosing Spondylitis|Fibroblast|Gene Expression|Cells, Cultured|RNA, Messenger|Immunohistochemistry|E2F Transcription Factors 40 CHD6 24755471 Cancer Res. 2014 10.1158/0008-5472.CAN-14-0013 112 2 15 261 Humans|*Colorectal Cancer|Microsatellite Instability|Exome|Mutation|DNA Copy Number Variations|Genomics|Phenotype|DNA Mismatch Repair|Sequencing, Whole Exome|transformation-transcription domain-associated protein|Adaptor Proteins, Signal Transducing|*B-Lymphocytes|*Colonic Neoplasms|Nuclear Proteins|Cell Line 31 CHD6 24694993 PLoS ONE 2014 PMC3973632 10.1371/journal.pone.0092553 24 4 2 261 Humans|*DNA Copy Number Variations|*Colorectal Cancer|Gene Dosage|Comparative Genomic Hybridization|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Genetic Predisposition to Disease|Genomics|PTPRT protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Transcriptome|*Colonic Neoplasms|Downregulation 31 CHI3L2 25477513 J. Biol. Chem. 2014 PMC4317009 10.1074/jbc.M114.588905 0 0 0 30 Humans|*Chitinase|oligochitosan|*Chitin|chitohexaose|Oligosaccharides|*Thermodynamic|Protein Conformation|Protein Binding|Crystallography, X-Ray|Catalytic Domain|Models, Molecular|Calorimetry|Carbohydrates|*Cartilage|CHI3L2 protein, human 35 CILP2 24633158 Nat. Genet. 2014 PMC4169222 10.1038/ng.2926 84 3 14 28 Humans|Mice|Animals|Genome-Wide Association Study|Norway|*Myocardial Infarction|Triglycerides|Exome|Cholesterol, HDL|Cholesterol, LDL|Genotype|Lipids|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|Lipid Metabolism|TM6SF2 protein, human|Membrane Proteins 34 CILP2 24498183 PLoS ONE 2014 PMC3907504 10.1371/journal.pone.0087735 13 1 0 28 Humans|Dogs|Animals|*Matrilin Proteins|Genome-Wide Association Study|*Hip Dislocation|Bayes Theorem|Canine Hip Dysplasia|Chromosome Mapping|Quantitative Trait Loci|Single Nucleotide Polymorphisms|*Hip Dislocation, Congenital|Genotype|Phenotype|Frequencies, Allele|Hip Joint|DNA|*Basement Membrane 34 CKAP2 25439729 Am. J. Hum. Genet. 2014 PMC4225581 10.1016/j.ajhg.2014.10.008 11 0 0 245 Child|Male|Humans|Animals|Mice|Filippi syndrome|*Microcephaly|*Intellectual Disability|*Facies|*Syndactyly|*Growth Disorders|*Mutations|Homozygote|Phenotype|Cytoskeletal Proteins 50 CKAP2 25189355 Mol. Cancer Res. 2014 PMC4336832 10.1158/1541-7786.MCR-14-0384-T 15 31 1 245 Humans|Male|Mice|Animals|*Cell Survival|*Prostate|*Prostate Cancer|PC3 Cells|ribosomal protein S6 kinase, 90kDa, polypeptide 3|Ribosomal Protein S6 Kinases, 90-kDa|Phosphorylation|Cell Line, Tumor|Neoplasm Proteins|Signal Transduction|Protein-Tyrosine Kinases|Bone Neoplasms|Cell Proliferation|*Bone|*Neoplastic Processes|Gene Knockdown Techniques|*Disease Progression|Cell Nucleus 50 CLIC6 25058583 JAMA Ophthalmol 2014 10.1001/jamaophthalmol.2014.2065 18 0 2 37 Humans|*Proteomics|*Choroid|Retinal Pigment Epithelium|Retina|Age Related Macular Degeneration|*Retinal Pigments|Eye Proteins|Eye Diseases 21 CLSTN2 25463516 Neuroscience 2014 PMC4298480 10.1016/j.neuroscience.2014.11.030 4 9 0 215 Animals|Humans|*Zebrafish|*Cadherins|Zebrafish Proteins|Embryo, Nonmammalian|Cell Adhesion|Cell Adhesion Molecules|Gene Expression Regulation, Developmental|Cell Movement|In Situ Hybridization|Nervous System|*Terminal Repeats 32 CLSTN2 25423262 PLoS ONE 2014 PMC4244101 10.1371/journal.pone.0113662 12 11 0 215 *Venlafaxine Hydrochloride|*Insulin|Depressive Disorder, Major|*Neuroplasticity|Antidepressant Drugs|Serotonin and Noradrenaline Reuptake Inhibitors|*Insulin, Regular, Human|*Neurites|*Signal Transduction|Hippocampus|Brain|Serotonin 32 CLSTN2 25080189 Neuropsychologia 2014 10.1016/j.neuropsychologia.2014.07.020 4 0 1 215 *Memory, Episodic|WWC1 protein, human|*Intracellular Signaling Peptides and Proteins|*Phosphoproteins|Memory Disorders|Cognition|Neuropsychological Tests|Genotype|Membrane Proteins|Alleles|Calcium-Binding Proteins|Mental Recall|Polymorphism, Single Nucleotide|*Depressive Disorder, Major 32 CMPK2 25122750 Nucleic Acids Res. 2014 PMC4176326 10.1093/nar/gku713 66 17 7 29 Humans|Mice|Animals|*RNA, Long Noncoding|*Antiviral Agents|Hepacivirus|Interferon-alpha|Hepatitis C|Hepatocytes|Janus Kinases|Virus Replication|Signal Transduction|Upregulation|Livers 21 CMPK2 25042677 J. Med. Virol. 2014 10.1002/jmv.24014 6 0 0 29 Animals|*Hepatitis E|*Monkeys|*Hepatitis B virus|Hepatitis E virus|Virus Cultivation|*Feces|RNA, Viral|Cell Line, Tumor|*Transcriptional Activation|*Upregulation|Genotype|Interferons 21 cornulin 24780931 J. Invest. Dermatol. 2014 PMC4260798 10.1038/jid.2014.204 12 0 2 53 Animals|trichohyalin|filaggrin|*Intermediate Filament Proteins|*Skin|Epidermis|*Morphogenesis|Sequences, Amino Acid|Hair|*Biological Evolution|Keratinocytes|Epithelium|Epidermal Cells|Hair Follicle|Nails|Feathers|S100 Proteins|Protein Precursors|Sequence Homology, Amino Acid 27 CRELD1 25524324 Pediatr Cardiol 2014 10.1007/s00246-014-1091-3 4 0 1 38 Humans|*Down Syndrome|*Endocardial Cushions|*Germ-Line Mutation|Atrioventricular Septal Defect|*Heart Septal Defects|Homeobox Protein Nkx-2.5|*Genes, Homeobox|Homeodomain Proteins|GATA4 Transcription Factor|Congenital Heart Defects|Septal Defects, Ventricular|Transcription Factors|Mutations|Heart Septal Defects, Atrial|Extracellular Matrix Proteins|NKX2-5 protein, human|CRELD1 protein, human|Cell Adhesion Molecules 32 CRELD1 25329542 PLoS ONE 2014 PMC4201535 10.1371/journal.pone.0110520 17 1 2 38 Humans|Swine|Animals|*Altitude|Tibet|*Adaptation, Physiological|*Acclimatization|Selection, Genetic|Genetics, Population|Biological Evolution|Hypoxia|Polymorphism, Single Nucleotide|Chinese|Genomics|NRBF2 protein, human|Trans-Activators|CCBE1 protein, human|Calcium-Binding Proteins|Tumor Suppressor Proteins 32 CRELD1 25328912 AIMS Genet 2014 PMC4200510 10.3934/genet.2014.1.1#sthash.jksuJTeC.dpuf 6 4 0 38 *Alleles|Atrioventricular Septal Defect|Heart Septal Defects|Heart Septal Defects, Atrial|Heart Septal Defects, Ventricular|Genetic Predisposition to Disease|Extracellular Matrix Proteins|Missense Mutation|Cell Adhesion Molecules|Down Syndrome 32 CRELD1 24927998 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2014 10.3760/cma.j.issn.1003-9406.2014.03.001 1 1 0 38 Atrioventricular Septal Defect|*Heart Septal Defects|Extracellular Matrix Proteins|Mutation|Amino Acid Sequence|Cell Adhesion Molecules|Down Syndrome 32 CRELD1 24697899 Dev. Cell 2014 10.1016/j.devcel.2014.02.012 5 3 1 38 Mice|Animals|*Calcineurin|NFATC Transcription Factors|Gene Expression Regulation|Signal Transduction|Cells, Cultured|Protein Transport|Phosphorylation|Cell Nucleus|Cytoplasm|Blotting, Western|Heart|Nfatc1 protein, mouse|CRELD1 protein, mouse|Cell Adhesion Molecules|Extracellular Matrix Proteins 32 CRELD1 24689825 Pediatr Int 2014 10.1111/ped.12349 7 0 2 38 Child|Humans|*Down Syndrome|*Pulmonary Arterial Hypertension|Atrioventricular Septal Defect|Heart Septal Defects|Artery, Pulmonary|Hypertension, Pulmonary|Heart Defects, Congenital|Prostacyclin|*Familial Primary Pulmonary Hypertension|Cardiac Catheterization|Vasodilator Agents|Lung|Endothelin-1|Administration, Inhalation|Lung Diseases, Obstructive|Nitric Oxide 32 CROCC 25537509 Oncotarget 2014 PMC4467411 10.18632/oncotarget.2950 8 0 0 82 Humans|Child|*Glioblastoma|*Exome|Brain Neoplasms|*Whole Exome Sequencing|Pilocytic Astrocytoma|High-Throughput Nucleotide Sequencing|Genetic Predisposition|Base Sequence|Polymorphism, Single Nucleotide|Cell Transformation, Neoplastic|Cell Line, Tumor|Genomics 32 CROCC 24695856 J. Cell. Sci. 2014 PMC4038944 10.1242/jcs.142331 20 35 3 82 Humans|*Phosphorylation|*Centrosome|Centrioles|Interphase|Cell Cycle Proteins|Spindle Apparatus|Mitosis|Protein-Serine-Threonine Kinases|Cell Cycle|NIMA-Related Kinases|Autoantigens|HeLa Cells|NEK2 protein, human|CEP135 protein, human|Carrier Proteins|Cep250 protein, human 32 CRTAC1 25034269 Mol. Cell. Neurosci. 2014 10.1016/j.mcn.2014.07.001 10 8 1 35 Mice|Animals|*Nogo Receptor 1|*Ligands|*Lotus|MAG protein, human|Myelin-Associated Glycoprotein|Myelin Proteins|RTN4 protein, human|Nogo Proteins|Growth Cones|Axons|TNFSF13B protein, human|B Lymphocyte Stimulator|Receptors, Cell Surface|Neurons|Dorsal Root Ganglion|Central Nervous System|GPI-Linked Proteins|Protein Binding 27 CRYBB3 25366320 BMC Genomics 2014 PMC4232633 10.1186/1471-2164-15-952 13 0 3 14 Animals|*Transcriptome|*Solea|Genome|Genomics|Gene Expression Profiling|Evolution, Molecular|Phylogeny 36 CRYGC 25475058 Cell Res. 2014 PMC4650588 10.1038/cr.2014.160 56 0 6 132 Male|Mice|Animals|*Gene Editing|*CRISPR-Cas Systems|*CRISPR|*Adult Germline Stem Cells|Spermatogenesis|DNA End-Joining Repair|Recombinational DNA Repair|Spermatids|Testes|Seminiferous Tubules|Gene Therapy 65 CSMD2 25189415 Leukemia 2014 10.1038/leu.2014.264 38 0 3 9 20 CSMD2 24718909 Clin. Chem. 2014 10.1373/clinchem.2013.213611 19 0 4 9 Humans|*Neoplastic Cells, Circulating|*Prognosis|*Melanoma|Skin Neoplasms|*Cell Count|Biomarkers, Tumor|*Genomics|*Neoplasms, Second Primary 20 CSMD2 24408017 Tumour Biol. 2014 10.1007/s13277-013-1581-6 14 0 1 9 Humans|CSMD3 protein, human|*Membrane Proteins|CSMD1 protein, human|*Colorectal Cancer|*Genes, Regulator|Prognosis|*Colonic Neoplasms|Mutation|mRNA|Downregulation 20 CST7 25086747 Nat. Cell Biol. 2014 PMC4249762 10.1038/ncb3011 89 9 7 128 Humans|cathepsin S|*Cathepsins|*Brain Cancer|Xenograft Model Antitumor Assays|Cell Line, Tumor|Tumor Microenvironment|Lung Neoplasms|Cell Movement|Kaplan-Meier Estimate|*Proteolysis|Brain 39 CST7 24934367 Cancer Biomark 2014 10.3233/CBM-140397 6 1 1 128 Child|Humans|*Craniopharyngioma|Neoplasm Recurrence, Local|CXCL12 protein, human|*Chemokine CXCL12|CXCR4 protein, human|*Receptors, CXCR4|*Signal Transduction|Pituitary Neoplasms 39 CST7 24702263 Protein Pept. Lett. 2014 10.2174/0929866521666140403124146 11 1 2 128 *Cystatin B|*Interleukin-2|Cystatins|*Natural Killer Cells|Cathepsin C|Granzymes|Cysteine Proteinase Inhibitors|Cathepsin L|T-Lymphocytes, Cytotoxic|Lysosomes|Endosomes|Cell Line|*Proteolysis|Cytoplasmic Granules|*Transcription Factors 39 CST8 25110652 Int J Genomics 2014 PMC4119616 10.1155/2014/208751 1 1 0 190 Rats|Animals|Gene Ontology|Protein Interaction Maps|*Femoral Fracture|Gene Expression Profiling|Gene Regulatory Networks|Computational Biology|Fracture Healing|Protein Interaction Mapping|Gene Expression Regulation, Neoplastic|Gene Expression 31 CTAGE1 25406034 J Eur Acad Dermatol Venereol 2014 10.1111/jdv.12743 2 0 1 3 Humans|*Mycosis Fungoides|Hair Follicle|Skin Neoplasms|Lymphoid Cells|Diagnosis, Differential 238 CTAGE1 25335433 Eur J Dermatol 2014 10.1684/ejd.2014.2436 2 2 0 3 Humans|*T-Lymphocytes, Regulatory|*Vitiligo|6-sulfo sialyl Lewis X|*CD8-Positive T-Lymphocytes|*Oligosaccharides|*Lewis X Antigen|Melanocytes|Cytotoxic T-Lymphocytes|Skin 238 CTAGE1 25181936 Cancer Sci. 2014 PMC4462380 10.1111/cas.12526 3 0 0 3 Humans|*Prognosis|Neoplasm Recurrence, Local|Lymphoma, Extranodal NK-T-Cell|*Concurrent Chemoradiotherapy|Herpesvirus 4, Human|Epstein-Barr Virus Infections|Viral Matrix Proteins|*Natural Killer T-Cell|Proportional Hazards Models|Treatment Outcome|Combined Modality Therapy|Viral Proteins|Killer Cells, Natural|Japan 238 CTAGE1 24916032 Mol. Biol. Evol. 2014 10.1093/molbev/msu188 7 0 2 3 Animals|Male|Humans|*Testis|*Genetic Evolution|Primate|Phylogeny|Gene Duplication|Sequence Alignment|Multigene Family|Genomes|Amino Acid Sequence|Hominidae|Chimpanzee|Exon|Cutaneous T Cell Lymphoma|Skin Neoplasms 238 CUZD1 24811052 Curr. Opin. Gastroenterol. 2014 10.1097/MOG.0000000000000076 8 0 1 24 Colitis, Ulcerative|Crohn Disease|*Inflammatory Bowel Disease|GPI-Linked Proteins|Autoantibodies|Fluorescent Antibody Technique, Indirect|Immunoglobulin A|Immunoglobulin G|Biomarkers|Membrane Proteins|Phenotype|Pancreas|Saccharomyces cerevisiae 35 CYP4X1 25055826 Am. J. Physiol., Cell Physiol. 2014 PMC4254955 10.1152/ajpcell.00401.2013 10 0 0 8 Animals|Rats|Endothelial Cells|CYP2C11 protein, rat|*Steroid 16-alpha-Hydroxylase|*Cytochrome P450 Family 2|*Aryl Hydrocarbon Hydroxylases|arachidonate epoxygenase|*Cytochrome P-450 Enzyme System|cytochrome P-450 4X1|Eicosanoids|Cerebral Blood Flow|Astrocytes|Arachidonic Acid|Cells, Cultured|Brain 26 CYTL1 24758934 Int J Mol Sci 2014 PMC4013671 10.3390/ijms15046941 2 6 0 57 Humans|Pregnancy|Female|Mice|Animals|*Chondrocytes|doublecortin protein|Neuropeptides|Microtubule-Associated Proteins|Mesenchymal Stem Cells|Articular Cartilage|*Phenotype|Cell Differentiation|Cells, Cultured|Aggrecan|RNA, Messenger|CYTL1 protein, human|Blood Proteins|Cytokines 34 DACH2 25234129 BMC Med. Genet. 2014 PMC4355004 10.1186/s12881-014-0105-6 3 0 0 37 Male|Humans|*Siblings|*Exome|ABCD1 protein, human|*ATP Binding Cassette Transporter, Subfamily D, Member 1|Adrenoleukodystrophy|*Phenotype|*Mutations|*Whole Exome Sequencing|DNA Mutational Analysis|ATP-Binding Cassette Transporters|Exons|Mutation, Missense 36 DACH2 25048735 PLoS ONE 2014 PMC4105537 10.1371/journal.pone.0102551 20 0 4 37 Pregnancy|Cattle|Animals|Female|Sexual Maturation|Genome-Wide Association Study|Fertility|Corpus Luteum|Transcriptome|Quantitative Trait Loci|Reproduction|Hypothalamus|Gland, Pituitary|Single Nucleotide Polymorphism|Ovary|Gene Expression Regulation|Phenotype|Uterus 36 DACH2 24435167 Mol. Cancer Res. 2014 10.1158/1541-7786.MCR-13-0337 11 0 0 37 Mice|Animals|*Chimeras|PAX5 Transcription Factor|Oncogene Proteins, Fusion|Transcription Factors|Gene Expression Regulation, Leukemic|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Cell Nucleus|Cell Line|B-Lymphocytes|Promoter Regions, Genetic|Pax5 protein, mouse 36 DAZ1 24935076 Mol. Hum. Reprod. 2014 10.1093/molehr/gau043 7 0 0 63 Humans|Male|*Azoospermia|*DNA Copy Number Variations|*Infertility, Male|Deleted in Azoospermia 1 Protein|Oligozoospermia|Y Chromosome, Human|*Number, Gene Copy|Spermatogenesis|Haplotypes|Asian Continental Ancestry Group|Limulus clotting factor C|*Arthropod Proteins|Seminal Plasma Proteins|*Serine Endopeptidases|Gene Deletion|Genetic Loci|Testis|RNA-Binding Proteins 205 DAZ1 24878370 Gene 2014 10.1016/j.gene.2014.05.061 1 0 1 63 Humans|Male|Child|*Infertility, Male|Deleted in Azoospermia 1 Protein|Oligospermia|Chromosomes, Human, Y|Spermatogenesis|Gene Deletion|Restriction Fragment Length Polymorphism|Chromosome Deletion|Gene Dosage|RNA-Binding Proteins|Chromosome Mapping|Polymerase Chain Reaction|Case-Control Studies|DAZ2 protein, human|DAZ4 protein, human 205 DAZ1 24876252 Plant Cell 2014 PMC4079371 10.1105/tpc.114.124743 19 0 3 63 Male|*Arabidopsis|Arabidopsis Proteins|*Cell Division|*Germ Cell|Gene Expression Regulation, Plant|Pollen|Transcription Factors|*Sperm|*Fertility|Promoter Regions, Genetic 205 DAZ1 24728569 J. 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Genet. 2014 PMC4048382 10.1007/s10815-014-0220-5 3 0 0 63 Humans|Male|Azoospermia, Nonobstructive|*Azoospermia|*Testis|*Semen|Sperm Retrieval|Spermatogenesis|Infertility, Male|Sperm|*Biopsy|*Bodily Secretions|*Body Fluids 205 DAZ3 24878370 Gene 2014 10.1016/j.gene.2014.05.061 1 0 1 1 Humans|Male|Child|*Infertility, Male|Deleted in Azoospermia 1 Protein|Oligospermia|Chromosomes, Human, Y|Spermatogenesis|Gene Deletion|Restriction Fragment Length Polymorphism|Chromosome Deletion|Gene Dosage|RNA-Binding Proteins|Chromosome Mapping|Polymerase Chain Reaction|Case-Control Studies|DAZ2 protein, human|DAZ4 protein, human 20 DEXI 25008175 Diabetes 2014 PMC4237999 10.2337/db13-1785 6 3 1 27 Humans|*Diabetes Mellitus, Type 1|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Allele|*Chromosome 13|Autoimmune Diseases|Monosaccharide Transport Proteins|Genotype|Lectins, C-Type|DNA-Binding Proteins|Case-Control Studies|Multiple Sclerosis|Suppressor of Cytokine Signaling Proteins|Suppressor of Cytokine Signaling 1 Protein|CLEC16A protein, human 30 DEXI 24388013 J. Allergy Clin. Immunol. 2014 PMC4280183 10.1016/j.jaci.2013.10.030 65 1 8 27 *Genome-Wide Association Study|*Rhinitis, Allergic, Seasonal|*Asthma|*Phenotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Eczema|Genotype|Alleles|Case-Control Studies|Risk Factors 30 DGCR2 24767651 Taiwan J Obstet Gynecol 2014 10.1016/j.tjog.2013.10.037 1 0 0 182 Humans|Female|Adolescent|Chromosome 22q11.2 Microduplication Syndrome|*Comparative Genomic Hybridization|*Autistic Disorder|*Menstruation|*Self Care|*Chromosome Duplication|*DiGeorge Syndrome|Abnormalities, Multiple|*Chromosomes, Human, Pair 22|Chromosome Deletion|Mental Retardation|*Monosomy|In Situ Hybridization, Fluorescence|Microcephaly 22 DGCR2 24616583 J. Korean Med. Sci. 2014 PMC3945129 10.3346/jkms.2014.29.3.351 9 3 0 182 Humans|*Urinary Bladder Neoplasms|Gene Expression Profiling|Muscle Neoplasms|Neoplasm Invasiveness|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|USP18 protein, human|*Endopeptidases|Risk Factors|ZNF699 protein, human|Carrier Proteins 22 DGCR6 24767651 Taiwan J Obstet Gynecol 2014 10.1016/j.tjog.2013.10.037 1 0 0 67 Humans|Female|Adolescent|Chromosome 22q11.2 Microduplication Syndrome|*Comparative Genomic Hybridization|*Autistic Disorder|*Menstruation|*Self Care|*Chromosome Duplication|*DiGeorge Syndrome|Abnormalities, Multiple|*Chromosomes, Human, Pair 22|Chromosome Deletion|Mental Retardation|*Monosomy|In Situ Hybridization, Fluorescence|Microcephaly 24 DHX33 25172487 J. Immunol. 2014 PMC4170004 10.4049/jimmunol.1401448 25 3 4 151 Humans|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|*E3 Ubiquitin Ligase|Caspase 1|Macrophages|*Cytosol|Interleukin-1beta|interleukin 18 protein, human|IL-18|Carrier Proteins|Monocytes|RNA, Double-Stranded|TRIM33 protein, human|Transcription Factors|Caspases|NLRP3 protein, human|DHX33 protein, human|DEAD-box RNA Helicases 25 DKKL1 24909558 Dev Neurobiol 2014 10.1002/dneu.22201 4 2 1 98 Humans|*Embryonal Carcinoma Stem Cells|*Retinoic Acid|DKK3 protein, human|*Intercellular Signaling Peptides and Proteins|Cell Differentiation|Neurogenesis|Neurons|Cell Cycle|Cell Proliferation|Signal Transduction|Cell Line, Tumor|mRNA|Transfection 22 DMRTA2 25489906 Mol. Endocrinol. 2014 PMC5414757 10.1210/me.2014-1176 1 1 1 12 Animals|*Zebrafish|*Gonadotrophs|*Corticotrophs|*Pituitary Gland|Zebrafish Proteins|*Cell Differentiation|*Pituitary Diseases|Embryo, Nonmammalian|Pituitary Gland, Anterior|Gene Expression Regulation, Developmental|Transcription Factors|Cell Lineage|Embryonic Development|Gene Knockdown|Neurogenesis|Sex Differentiation 25 DMRTA2 25082981 Mol. Hum. Reprod. 2014 10.1093/molehr/gau058 8 0 1 12 Male|Female|Humans|Mice|Animals|*RNA Interference|*Transcription Factor 3|*Heterografts|*Transplantation, Heterologous|Mice, Nude|Oogonia|Ovaries|Meiosis|*Cell Differentiation|TCF3 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Germ Cells|Embryonic Germ Cells|Testis|Gene Expression Regulation, Developmental|Transcription Factors|Ovarian Follicle|mRNA 25 DMRTA2 24668652 Zool. Res. 2014 PMC5042934 10.11813/j.issn.0254-5853.2014.2.099 0 0 0 12 Humans|Animals|Male|Female|*Osmeriformes|*Larvae|Phylogeny|cDNA|Cloning, Molecular|mRNA|Amino Acid Sequence|Fish Proteins|Sequence Alignment|Base Sequence|Real-Time Polymerase Chain Reaction|Ovary 25 DMXL2 25248098 PLoS Biol. 2014 PMC4172557 10.1371/journal.pbio.1001952 17 6 0 56 Humans|Male|Mice|Animals|*Gonadotropin Releasing Hormone|*Haploinsufficiency|Homozygote|Sexual Maturation|Sequence Deletion|Luteinizing Hormone|Kisspeptins|*Infertility|Follicle Stimulating Hormone|Hypothalamus|*Neurons|Pituitary Gland|Fertility|Nerve Tissue Proteins|Gonadotrophs|DMXL2 protein, human|Adaptor Proteins, Signal Transducing|DMXL2 protein, mouse 27 dnajc10 25055872 Hum. Mol. Genet. 2014 PMC4240209 10.1093/hmg/ddu385 12 26 1 331 *Reductase|*Molecular Chaperones|molecular chaperone GRP78|Heat-Shock Proteins|Endoplasmic Reticulum|Rhodopsin|HSP40 Heat-Shock Proteins|Protein Folding|Retinitis Pigmentosa|Protein Transport|Substitutions, Amino Acid|Mutations|*Quality Control 32 DOC2A 25005332 Diabetologia 2014 10.1007/s00125-014-3312-y 13 6 0 31 *Insulin Secretion|B-insulin|*Insulin|*Insulin, Regular, Human|Glucose|*Biological Transport|Islets of Langerhans|*Isoforms|Calcium-Binding Proteins|Insulin Resistance|Nerve Tissue Proteins|Exocytosis|Homeostasis|Muscle, Skeletal|Biotin 42 DOC2A 24867541 Int. J. Radiat. Oncol. Biol. Phys. 2014 PMC4464555 10.1016/j.ijrobp.2014.03.035 2 1 1 31 Humans|Male|Pilot Projects|*Prostate|Prostate-Specific Antigen|Prostatic Neoplasms|EZH2 protein, human|Enhancer of Zeste Homolog 2|Prognosis|Neoplasm Staging|Biomarkers, Tumor|Kaplan-Meier Estimate|Disease-Free Survival|Polycomb Repressive Complex 2|*GTPase-Activating Proteins|DAB2 protein, human|Tumor Suppressor Proteins|Adaptor Proteins, Signal Transducing|DAB2IP protein, human|ras GTPase-Activating Proteins 42 DRAM2 25126724 Autophagy 2014 PMC4198358 10.4161/auto.29592 16 5 3 31 Humans|Mice|Animals|*Leukemia, Promyelocytic, Acute|*Transcription Factors|*Autophagy|Tretinoin|*Oncogene Proteins|Oncogene Proteins, Fusion|Cell Differentiation|*Lysosomes|Proteolysis|Antineoplastic Agents|Cell Line, Tumor|Hematopoiesis|DRAM2 protein, human|Membrane Proteins 21 DRP2 25462567 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.11.065 9 5 1 48 *Arabidopsis|*Dynamin|Arabidopsis Proteins|*Golgi Apparatus|*Protein Transport|trans Golgi Network|Plasma Membrane|TYRP1 protein, human|Plant Roots|*Membrane Glycoproteins|Plants, Genetically Modified|Clathrin|Endocytosis|Wortmannin|Microscopy, Fluorescence|Confocal Laser Scanning Microscopy|Green Fluorescent Proteins|DRP2B protein, Arabidopsis 49 DRP2 25250163 Iran J Cancer Prev 2014 PMC4171831 2 6 0 48 dihydropyrimidinase|*Astrocytoma|*Proteomics|*Amidohydrolases|Electrophoresis, Gel, Two-Dimensional|*Brain Neoplasms|*Protein Processing, Post-Translational|Proteins|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Brain 49 DRP2 25237312 Front Plant Sci 2014 PMC4154393 10.3389/fpls.2014.00408 9 11 1 48 Animals|*Dynamin|*Golgi Apparatus|Arabidopsis Proteins|Arabidopsis|GTPases|TYRP1 protein, human|Plant Proteins|*Membrane Glycoproteins|Protein Transport|Endocytosis 49 EHBP1 24722856 Sci China Life Sci 2014 10.1007/s11427-014-4650-1 2 0 0 98 Humans|Early Detection of Cancer|*Colorectal Cancer|Gene Regulatory Networks|Signal Transduction|Gene Expression Regulation, Neoplastic|Transcription Factors|*Colonic Neoplasms|Gene Expression Profiling|Upregulation|Software|Protein Binding|*Screening|Transcriptional Activation|KLK6 protein, human|Kallikreins 29 EHBP1 24451147 Carcinogenesis 2014 10.1093/carcin/bgu019 18 2 3 98 Humans|Male|*Atorvastatin|*Adenosine Triphosphate|PTEN protein, human|*PTEN Phosphohydrolase|*Signal Transduction|Heptanoic Acids|Proto-Oncogene Proteins c-akt|Statins|*Prostate Cancer|Pyrroles|*Prostate|Phosphorylation|Cell Nucleus|Cell Migration|Cell Line, Tumor|Cell Proliferation|Mevalonate 29 EIF1AY 24741625 J Immunol Res 2014 PMC3987971 10.1155/2014/814598 17 40 2 31 Humans|Male|Female|*Incidence|*Healthy Volunteers|*Estrogens|*B Cells|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation|*Sex Factors|Signal Transduction|Gene Expression|Upregulation 26 ENOSF1 25027354 Sci Rep 2014 PMC4100023 10.1038/srep05697 3 2 0 12 Humans|*Thymidine Phosphorylase|*Platelet Count|Dihydrouracil Dehydrogenase (NADP)|Fluorouracil|Antimetabolites, Antineoplastic|Thymidylate Synthase|Prognosis|Colorectal Neoplasms|Immunohistochemistry|Chemotherapy, Adjuvant|Gene Expression Regulation, Neoplastic|*Antimetabolites|Biomarkers, Tumor|*Gastrointestinal Cancer 23 ENOSF1 24647007 Gut 2014 PMC4283622 10.1136/gutjnl-2013-306571 20 5 3 12 Humans|*Dehydrogenase, Dihydropyrimidine|*Capecitabine|*Thymidylate Synthase|Fluorouracil|*Colorectal Cancer|Antimetabolites, Antineoplastic|Deoxycytidine|Polymorphism, Genetic|*Colonic Neoplasms|Genetic Markers|TYMS protein, human 23 ENOSF1 24583629 Pharmacogenet. Genomics 2014 10.1097/FPC.0000000000000036 11 0 1 12 Humans|*Methotrexate|*Pharmacogenetics|*Rheumatoid Arthritis|Antirheumatic Agents|Methylenetetrahydrofolate Reductase (NADPH2)|Thymidylate Synthase|Genotype|Gene Frequency|Polymorphism, Single Nucleotide|Severity of Illness Index|TYMS protein, human 23 EPB41L4B 24820650 Int. J. Mol. Med. 2014 10.3892/ijmm.2014.1775 7 1 1 90 Endothelial Cells|radixin|Cytoskeletal Proteins|ezrin|Membrane Proteins|*Movements, Cell|moesin|Microfilament Proteins|Cell Membrane|TYRP1 protein, human|*Membrane Glycoproteins|*Wound Healing|Protein Binding 23 EPC2 25522910 Environ. Microbiol. 2014 10.1111/1462-2920.12742 8 0 0 66 Phylogeny|RNA, Ribosomal, 16S|Pacific Ocean|Prochlorococcus|Synechococcus|Seawater|DNA, Ribosomal Spacer|System, Ecological 54 EPC2 25230976 Genes Chromosomes Cancer 2014 PMC4304365 10.1002/gcc.22211 5 4 0 66 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Translocation, Genetic|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|*Transcriptome Analysis|Sequencing, RNA|Kidney|Gene Expression Regulation, Neoplastic|RNA, Messenger|Carcinogenesis|Cohort Studies 54 ERMN 25525853 Future Oncol 2014 10.2217/fon.14.149 5 0 1 57 *Hepatoblastoma|*Oncogenes|Liver Neoplasms|Chromosome Aberrations|*Transcriptional Activation|Liver|*Upregulation|Aneuploidies 24 ERMN 24482476 Science 2014 PMC4157572 10.1126/science.1247363 165 3 21 57 *Whole Exome Sequencing|*Exome|Spastic Paraplegias, Hereditary|*Motor Neuron Diseases|*Neurons|Mutations|Corticospinal Tract|*Neurodegenerative Disorders|Pedigree|Phenotype|*Motor Disorders 24 ESX1 25505644 Microbiol Spectr 2014 PMC4259119 10.1128/microbiolspec.MGM2-0022-2013 12 3 1 100 *Gene Transfer, Horizontal|*Mycobacteria|Conjugation, Genetic|Mycobacterium smegmatis|Genome, Bacterial|DNA, Bacterial|Sequencing, Whole Genome|Genomics 73 ESX1 25316452 Hum. Reprod. 2014 10.1093/humrep/deu261 6 0 0 100 Humans|Male|*Azoospermia|*Spermatogenesis|Sperm Retrieval|Testis|Infertility, Male|Spermatozoa|mRNA|*Bodily Secretions|*Body Fluids 73 ESX1 25172123 Neurobiol. Aging 2014 10.1016/j.neurobiolaging.2014.07.033 15 0 1 100 *Neurogenesis|*Hippocampus|Dentate Gyrus|Neural Stem Cells|Bromodeoxyuridine|NES protein, human|Nestin|Cell Differentiation|Neurons|Cell Proliferation|Microtubule-Associated Proteins|Cell Count|Cell Survival 73 ESX1 24874799 PLoS Pathog. 2014 PMC4038636 10.1371/journal.ppat.1004183 40 3 4 100 *Mycobacterium tuberculosis|Proteomics|Operon|Gene Expression Regulation, Bacterial|Virulence|Antigens, Bacterial|Bacterial Proteins|Virulence Factors|Regulon|*Non-Coding RNA|Promoter Regions, Genetic 73 ESX1 24631198 Tuberculosis (Edinb) 2014 PMC4066952 10.1016/j.tube.2014.01.004 3 6 0 100 Humans|CX3CL1 protein, human|*Chemokine CX3CL1|*Chemotaxis|*Mycobacterium tuberculosis Infection|Mycobacterium tuberculosis|Macrophages|Monocytes|Granuloma|Virulence|Bacterial Proteins|Cells, Cultured 73 ESX1 24599289 Biol. Reprod. 2014 PMC4076385 10.1095/biolreprod.113.113910 14 0 1 100 Humans|Mice|Female|Pregnancy|Animals|*Placental Development|Embryo Implantation|Embryonic Development|Placenta|Trophoblast|Fetal Development|Embryo, Mammalian|*Prenatal Care|*Fetus|Ovulation|Fertility|Zinc 73 ESX1 26082110 Microbiol Spectr 2014 10.1128/microbiolspec.MGM2-0022-2013 5 0 1 100 *Gene Transfer, Horizontal|Genome-Wide Association Study|*Mycobacteria|Conjugation, Genetic|Mycobacterium smegmatis|Genome, Bacterial|DNA, Bacterial|Sequencing, Whole Genome|Genomics|DNA Sequence|Mosaicism|Biofilms 73 ETV7 25401416 Oncotarget 2014 PMC4322992 10.18632/oncotarget.2545 15 21 1 205 Humans|*Tumor Suppressor Protein p53|*Cell Plasticity|NF-kappa B|TNFalpha|Doxorubicin|MCF7 Cells|Signal Transduction|Transcriptional Activation|Cell Line, Tumor|Apoptosis|Gene Expression Regulation, Neoplastic|Up-Regulation|Transcription Factors|Cell Proliferation|Transfection 43 ETV7 24680656 Virus Res. 2014 10.1016/j.virusres.2014.03.009 7 1 1 205 Animals|*Avian Leukosis Virus|*Bursa of Fabricius|*Chickens|Avian Leukosis|Poultry Diseases|Gene Expression Profiling|Immunosuppression 43 ETV7 24657168 Mol. Cell 2014 PMC4011022 10.1016/j.molcel.2014.02.020 43 125 2 205 Humans|Mice|Animals|*Phosphorylation|*Tumor Suppressor Protein p53|*Diphosphates|*Inositol|PRKDC protein, human|*DNA-Activated Protein Kinase|Nuclear Proteins|Signal Transduction|Ataxia Telangiectasia Mutated Proteins|Cell Cycle Proteins|DNA-Binding Proteins|Tumor Suppressor Proteins|inositol hexakisphosphate kinase|Phosphotransferases (Phosphate Group Acceptor)|Apoptosis|Casein Kinase II|DNA Damage|*Cell Death 43 FAIM3 25257173 Cell Death Differ. 2014 PMC4262783 10.1038/cdd.2014.138 8 0 1 72 Mice|Rats|Animals|CD8-Positive T-Lymphocytes|Lymphocytic choriomeningitis virus|Lymphocytic Choriomeningitis|*Cell Differentiation|Lymphocyte Activation|Dendritic Cells|Epitopes, T-Lymphocyte|Mice, Knockout|Mice, Inbred C57BL|Autoimmune Diabetes|TOSO protein, mouse 23 FAIM3 25116093 Curr. Top. Microbiol. Immunol. 2014 10.1007/978-3-319-07911-0_1 9 0 1 72 Humans|Mice|Animals|immunoglobulin M receptor|*Fc Receptor|secretory IgM|Immunoglobulin M|B-Lymphocytes|Lymphocyte Activation|fas Receptor|Self-Antigens 23 FAIM3 24398517 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC3903229 10.1073/pnas.1323166111 14 0 2 72 Mice|Animals|*T-Lymphocytes, Regulatory|Experimental Autoimmune Encephalomyelitis|Th17 Cells|Th1 Cells|Dendritic Cells|Immune Tolerance|Lymphocyte Activation|Interleukin-10|Autoimmunity|Mice, Inbred C57BL|Cell Differentiation|*Encephalitis|Multiple Sclerosis|TOSO protein, mouse 23 FAM167A 25470816 PLoS ONE 2014 PMC4254283 10.1371/journal.pone.0113197 1 3 0 62 Humans|*Single Nucleotide Polymorphism|*Asian Continental Ancestry Group|*Study, Genetic Association|Genetic Predisposition to Disease|*Sclerosis, Systemic|Haplotypes|Gene Frequency|Genome-Wide Association Study|Case-Control Studies|Proteins|Nucleotides|FAM167A-BLK protein, human 25 FAM167A 24702955 Am. J. Hum. Genet. 2014 PMC3980411 10.1016/j.ajhg.2014.03.008 24 2 3 62 *Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|*B Cells|Polymorphism, Single Nucleotide|*Lupus Erythematosus, Discoid|*Promoter Regions, Genetic|Alleles|src-Family Kinases|Genotype|Case-Control Studies 25 FAM167A 24632671 PLoS ONE 2014 PMC3954551 10.1371/journal.pone.0090019 4 3 0 62 Humans|*Dermatomyositis|Japan|*STAT4 Transcription Factor|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Gene Frequency|Alleles|Genotype|Case-Control Studies|STAT4 protein, human|BLK protein, human|src-Family Kinases 25 farp1 24899721 J. Neurosci. 2014 PMC4044256 10.1523/JNEUROSCI.3950-13.2014 16 6 1 105 Rats|Animals|*Semaphorin-3A|Dendrites|Neurons|plexin|Nerve Tissue Proteins|Neurogenesis|Hippocampus|Signal Transduction|Semaphorin|Synapsins|F-Actin|Neuropilin-1|Cells, Cultured|Cell Adhesion Molecules|RhoGEF 26 FASTK 25466893 FASEB J. 2014 10.1096/fj.14-263822 14 10 0 83 Humans|*Carcinoma, Hepatocellular|FASLG protein, human|*Fas Ligand Protein|Liver Neoplasms|*Apoptosis|TYRP1 protein, human|fas Receptor|B virus, Hepatitis|Hepatitis B Virus Infection|Hepatocytes|Downregulation|*Cell Line|Up-Regulation|*Hepatitis B Antibodies|Transcriptional Activation|mRNA|Viral Core Proteins 24 FASTKD2 25448601 Neurobiol. Aging 2014 PMC4315763 10.1016/j.neurobiolaging.2014.09.027 55 3 9 49 Humans|Aged|*Alzheimer Disease|*Astrocytes|Amyloid beta-Peptides|*Mitochondria|ApoE4|Brain|Cognitive Dysfunction|Posterior Cingulate|Transcriptome|FASTKD2 protein, human|Protein-Serine-Threonine Kinases|Trmt61B protein, human|tRNA Methyltransferases 22 FASTKD2 25409762 BMC Cancer 2014 PMC4256816 10.1186/1471-2407-14-852 4 20 0 49 Humans|Male|*Serine Threonine Kinase|*Apoptosis|*Prostate Cancer|*Prostate|Nuclear Proteins|DNA-Binding Proteins|Cell Line, Tumor|Transcription Factors|Receptors, Androgen|Androgens|Phosphorylation|Gene Expression Regulation, Neoplastic|FASTKD2 protein, human 22 FASTKD2 25385369 Mol. Psychiatry 2014 PMC4427556 10.1038/mp.2014.142 16 2 5 49 Humans|Aged|*Memory|*Hippocampus|Memory Loss|Alzheimer Disease|Atrophy|Aging|Heterozygote|Signal Transduction|FASTKD2 protein, human|Protein-Serine-Threonine Kinases 22 FBXO45 25460509 Oncotarget 2014 PMC4359269 10.18632/oncotarget.2825 27 35 4 190 *Epithelial-Mesenchymal Transition|*Transcription Factors|TWIST1 protein, human|Twist-Related Protein 1|Nuclear Proteins|Homeodomain Proteins|Zinc Finger E-box-Binding Homeobox 1|Snail Family Transcription Factors|Ubiquitination|F-Box Proteins|Ubiquitin-Protein Ligases|Gene Expression Regulation, Neoplastic|Downregulation|Signal Transduction|Proteasome|Cell Line, Tumor|Ubiquitins 33 FBXO45 25326385 J. Biol. Chem. 2014 PMC4263871 10.1074/jbc.M114.614065 10 3 1 190 Animals|Mice|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Axons|F-Box Proteins|Animals, Genetically Modified|Synapses|Guanine Nucleotide Exchange Factors|Neurons|Neurogenesis|Ubiquitin-Protein Ligases|Signal Transduction|Ubiquitination|Protein Binding|Amino Acid Sequence|MAP Kinase Signaling System|Ubiquitins|RPM-1 protein, C elegans 33 FCRL1 24797767 Immunology 2014 PMC4212948 10.1111/imm.12311 2 3 1 2 Humans|*Antibodies, Monoclonal|Receptors, Antigen, B-Cell|*Signal Transduction|B Cells|*Downregulation|Phosphorylation|Lymphocyte Activation|Hybridomas|Mitogen-Activated Protein Kinases|Receptors, Fc|FCRL1 protein, human|Membrane Proteins|FCRL2 protein, human|Receptors, Cell Surface 34 FCRL1 24610777 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC3970507 10.1073/pnas.1401343111 38 0 6 2 Humans|*T-Lymphocytes, Regulatory|CTLA4 protein, human|CTLA-4 Antigen|Forkhead Transcription Factors|Interleukin-2 Receptor alpha Subunit|Cell Differentiation|Diabetes Mellitus, Type 1|Gene Expression Profiling|FCRL1 protein, human|Membrane Proteins 34 FCRL1 24504816 2014 PMC5823695 10.1002/art.38222 4 14 1 2 Humans|*Cryoglobulinemia|*Hepacivirus|*Immunotoxins|*Fc Receptor|*Hepatitis C|*B Cells|Receptors, Complement 3d|*Vasculitis|Lymphocyte Activation|*Lymphoid Tissue|Rheumatoid Factor 34 FERD3L 25388417 Stroke 2014 10.1161/STROKEAHA.114.007213 24 0 3 19 *Alleles|Genome-Wide Association Study|*Atherosclerosis|*Stroke|HDAC9 protein, human|Histone Deacetylases|Repressor Proteins|Plaque, Atherosclerotic|Carotid Artery Diseases|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Coronary Artery Disease|Case-Control Studies 21 FERD3L 24401371 Development 2014 10.1242/dev.104372 6 1 1 19 Mice|Animals|*Spinal Cord|Transcription Factors|Homeodomain Proteins|Neural Tube|Hepatocyte Nuclear Factor 3-beta|Body Patterning|Gene Expression Regulation, Developmental|Progenitor Cells|Nerve Tissue Proteins|Zebrafish Proteins|Neurons|Cell Differentiation|Mice, Knockout 21 fes1 24671421 J. Biol. Chem. 2014 PMC4036327 10.1074/jbc.M113.530014 24 0 4 198 Humans|*Saccharomyces cerevisiae|*Heat Shock Protein 70|Saccharomyces cerevisiae Proteins|Heat-Shock Protein 110|Molecular Chaperones|*Cytosol|*Yeast, Dried|*Nucleotides|Protein Folding|HSP90 Heat-Shock Proteins|Heat Shock Protein|BCL2-associated athanogene 1 protein|DNA-Binding Proteins|Protein Biosynthesis|structure-specific endonuclease I|Endonucleases|Protein Binding|Transcription Factor 35 FJX1 25150169 FEBS Lett. 2014 10.1016/j.febslet.2014.08.014 0 1 0 72 Animals|*Phosphorylation|*Cadherins|Drosophila|Drosophila Proteins|Drosophila melanogaster|Cell Polarity|Amino Acid Sequence|Signal Transduction|Vertebrate 26 FJX1 24558106 Arterioscler. Thromb. Vasc. Biol. 2014 10.1161/ATVBAHA.113.303001 26 3 2 72 Humans|Animals|*Endothelial Progenitor Cells|*Coronary Artery Disease|Neovascularization, Physiologic|Hindlimb|MicroRNAs|Ischemia|Cell Movement|Cell Proliferation|Stem Cells|Cell Differentiation|Cells, Cultured|Vascular Endothelial Growth Factor A|Regional Blood Flow|Muscle, Skeletal|Biomarkers|MIRN31 microRNA, human|MIRN720 microRNA, human 26 FLVCR2 25131804 Birth Defects Res. Part A Clin. Mol. Teratol. 2014 10.1002/bdra.23288 0 0 0 41 Humans|Pregnancy|Female|Infant, Newborn|*Hydranencephaly|*Cocaine|*Prenatal Exposure Delayed Effects|*Mutation|Hydrocephalus|Brain|Membrane Transport Proteins|Receptors, Virus|Syndrome|FLVCR2 protein, human 22 FLVCR2 24782769 Front Pharmacol 2014 PMC3986552 10.3389/fphar.2014.00061 57 65 2 41 *Heme b|*Cell Membranes|Hemopexin|*Protein Transport|iron protoporphyrin IX|Protoporphyrins|Heme Oxygenase-1|Oxidative Stress|Signal Transduction|*Cell Movement 22 FMN1 25303678 PLoS ONE 2014 PMC4193873 10.1371/journal.pone.0110198 5 2 1 3571 Male|Humans|DNA Copy Number Variations|Comparative Genomic Hybridization|*Obsessive Compulsive Disorder|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Attention Deficit-Hyperactivity Disorder|Autism|Brain|Cohort Studies 42 FMN1 24760772 Hum. Mol. Genet. 2014 PMC4119417 10.1093/hmg/ddu186 9 2 0 3571 Humans|Mice|Animals|*Growth Plate|*Filamins|*Chondrocytes|*Formins|*Cell Differentiation|Actin Cytoskeleton|Bone and Bones|Signal Transduction|Mice, Knockout|Gene Expression Regulation, Developmental|Hypertrophy|Cell Proliferation 42 FNDC1 24632710 PLoS ONE 2014 PMC3954831 10.1371/journal.pone.0091980 5 24 0 16 Humans|*Myocytes, Cardiac|*Signal Transduction|*G Protein|*Hypoxia|GJA1 protein, human|Connexin43|Apoptosis|CASP3 protein, human|Caspase 3|Intracellular Signaling Peptides and Proteins|Cell Hypoxia|Myocardium|*Peptides 29 foxd4 25234468 Mol. Cells 2014 PMC4213760 10.14348/molcells.2014.0227 11 43 0 58 Animals|*Neural Stem Cells|Neurogenesis|Central Nervous System|Glia|Neurons|Cell Differentiation|Transcription Factors|Multipotent Stem Cells|Induced Pluripotent Stem Cells|Gene Expression Regulation, Developmental|Cells, Cultured|Regulatory Network, Gene 27 FOXI3 24780628 Dev. Biol. 2014 PMC4070591 10.1016/j.ydbio.2014.04.014 18 24 0 37 Animals|Chick Embryo|*Ectoderm|Neural Plate|Ear, Inner|Gastrula|Gene Expression Regulation, Developmental|*Chickens|Fibroblast Growth Factors|Embryonic Development|In Situ Hybridization|Signal Transduction|Transcription Factors 30 FOXI3 24650709 Dev. Biol. 2014 PMC4013273 10.1016/j.ydbio.2014.03.004 18 12 1 37 Animals|Mice|*Branchial Region|*Transcription Factors|Neural Crest|Zebrafish|Zebrafish Proteins|Endoderm|Ectoderm|Body Patterning|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Signal Transduction|Fibroblast Growth Factors|Skull|Cell Movement|Apoptosis|Foxi3 protein, mouse|Forkhead Transcription Factors|foxi1 protein, zebrafish 30 FOXI3 24526262 Fish Physiol. Biochem. 2014 10.1007/s10695-014-9919-6 5 0 2 37 Animals|*Oreochromis niloticus|*Phylogeny|*Foxes|*Gonads|*Genome|Sex Differentiation|Transcriptome|Gene Expression Profiling|Gene Cluster|Real-Time Polymerase Chain Reaction 30 FOXI3 24393477 Differentiation 2014 10.1016/j.diff.2013.11.004 14 0 0 37 Humans|Mice|Animals|*Ferrets|*Teeth|Odontogenesis|Tooth Germs|BMP4 protein, human|Bone Morphogenetic Protein 4|Mesenchyme|Homeodomain Proteins|Transcription Factors|Hedgehog Proteins|Morphogenesis|Fibroblast Growth Factors|SOX2 protein, human|SOXB1 Transcription Factors|Gene Expression Regulation, Developmental|Signal Transduction|Molar|RUNX2 protein, human 30 FOXJ3 25137261 Nutr Hosp 2014 10.3305/nh.2014.30.1.7521 0 0 1 127 Mice|Animals|*Mice, Obese|*Promoter Regions, Genetic|DNA Methylation|*Diet|Epigenesis, Genetic|Obesity|*Biomarkers|Gene Expression|Genome-Wide Association Study 21 FOXJ3 24846831 Life Sci. 2014 10.1016/j.lfs.2014.05.006 0 6 0 127 *Cell Proliferation|*Lung Cancer|MicroRNAs|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|3' Untranslated Regions|Cell Line, Tumor|Down-Regulation|Cell Cycle|*Neoplastic Processes|Apoptosis 21 FOXN2 25049955 Asian-australas. J. Anim. Sci. 2014 PMC4093258 10.5713/ajas.2013.13385 6 4 4 138 Swine|Animals|*Genome-Wide Association Study|*Breeding|*Phenotype|*Meat|Quantitative Trait Loci|Genotype|SNPs|Sus scrofa|Haplotypes|Red Meat 28 FOXN2 24598159 Development 2014 PMC3957374 10.1242/dev.101436 32 0 4 138 28 FOXN4 25369423 Dev Neurobiol 2014 10.1002/dneu.22244 5 1 0 65 *Interneurons|Transcription Factors|Homeodomain Proteins|Spinal Cord|Eye Proteins|Motor Neurons|GATA2 protein, human|*GATA2 Transcription Factor|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Neural Stem Cells|Cell Lineage|Signal Transduction|Neurogenesis 54 FRMD4A 25540427 Mol. Biol. Cell 2014 PMC4325841 10.1091/mbc.E14-11-1554 3 10 1 33 Animals|*Drosophila|*Cytoskeleton|Drosophila Proteins|Drosophila melanogaster|Guanine Nucleotide Exchange Factors|Embryo, Nonmammalian|Actins|Plasma Membrane|*Microtubules|Embryonic Development|*Embryo, Mammalian|Steppke protein, Drosophila 26 FRMD4A 25480659 Arch. Toxicol. 2014 10.1007/s00204-014-1426-0 21 0 5 33 Humans|Child|Female|Pregnancy|*DNA Methylation|*Cigarette Smoking|*Prenatal Exposure Delayed Effects|*B-DNA|Maternal Exposure|Epigenesis, Genetic|Smoking|Blood, Cord|Placenta|*Epigenetic|CYP1A1 protein, human|CYP1A1|Fetal Development|*Tobacco|*Lifestyle 26 FRMD4A 25388005 Eur. J. Hum. Genet. 2014 PMC4795192 10.1038/ejhg.2014.241 6 1 2 33 Humans|*Microcephaly|*Intellectual Disability|*Homozygote|*Mutation|*Syndrome|Mutation, Frame Shift|Exome|Pedigree|Lod Score|Genetic Linkage 26 FRMD4A 25281018 Neurobiol. Aging 2014 10.1016/j.neurobiolaging.2014.09.003 14 2 4 33 Humans|*Alzheimer Disease|*Transcriptome|Amyloid beta-Peptides|Secretase|*Brain|tau Proteins|TREM2 protein, human|Receptors, Immunologic|Hydrocephalus, Normal-Pressure|Membrane Glycoproteins|Phosphorylation|Adaptor Proteins, Signal Transducing|Biomarkers 26 FRMD4A 24964093 PLoS ONE 2014 PMC4070909 10.1371/journal.pone.0099716 46 6 3 33 Humans|Pregnancy|Child|Female|*Tobacco Smoke Pollution|*DNA Methylation|CpG Islands|Epigenesis, Genetic|Smoking|Prenatal Exposure Delayed Effects|Genome-Wide Association Study|DNA 26 FXYD5 25400815 Int J Clin Exp Pathol 2014 PMC4230055 16 0 0 129 Mice|Animals|MicroRNAs|Gene Expression Regulation, Neoplastic|Melanoma, Cutaneous Malignant|Melanoma|Skin Neoplasms|Cell Line, Tumor|Cell Movement|CDH1 protein, human|Cadherins|Signal Transduction|Upregulation|Antigens, CD 81 FXYD5 24934367 Cancer Biomark 2014 10.3233/CBM-140397 6 1 1 129 Child|Humans|*Craniopharyngioma|Neoplasm Recurrence, Local|CXCL12 protein, human|*Chemokine CXCL12|CXCR4 protein, human|*Receptors, CXCR4|*Signal Transduction|Pituitary Neoplasms 81 FXYD5 24717576 Am. J. Physiol., Cell Physiol. 2014 10.1152/ajpcell.00042.2014 2 3 1 129 Mice|Animals|*Sodium-Potassium-Exchanging ATPase|Membrane Proteins|Membrane Glycoproteins|Neoplasm Proteins|Tumor Cell Lines|Cell Motility|Epithelial Cells|FXYD5 protein, mouse 81 GABRG1 25124326 Am. J. Med. Genet. A 2014 PMC4205182 10.1002/ajmg.a.36714 26 2 4 26 Humans|Female|Child|*Intellectual Disability|*Epilepsy|GABRA6 protein, human|GABA A Receptor|Mutations|Sequencing, Whole Exome|Genotype|Autism|Mutation, Missense|GABRA2 protein, human|GABRB2 protein, human 48 GABRP 25407308 Mol. Biol. Rep. 2014 10.1007/s11033-014-3834-x 12 0 4 19 Humans|Receptor, ErbB-2|Prognosis|Biomarkers, Tumor|Immunohistochemistry|CD44 protein, human|Hyaluronan Receptors|*Epithelium|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Tissue Array Analysis|Profile, Gene Expression|GABRP protein, human|Receptors, GABA-A 40 GABRP 25373323 Mol Med Rep 2014 10.3892/mmr.2014.2863 2 0 0 19 Female|Humans|ERBB2 protein, human|Receptor, ErbB-2|*Gene Expression Profiling|Prognosis|Carcinoma, Ductal, Breast|Genes, erbB-2|Receptors, Estrogen|Biomarkers, Tumor|Immunohistochemistry|Oligonucleotide Array Sequence Analysis|Profile, Gene Expression|In Situ Hybridization|Neoplasm Staging|Genes, cdc|*Breast Neoplasms|STC2 protein, human|Glycoproteins|Intercellular Signaling Peptides and Proteins 40 GABRP 25012653 J. Biol. Chem. 2014 PMC4148843 10.1074/jbc.M114.593582 18 8 5 19 Humans|*Receptors, GABA-A|*MAP Kinase Signaling System|progesterone receptor B|Progesterone Receptor|ERBB2 protein, human|Receptor, ErbB-2|Receptors, Estrogen|*Cell Migration|Biomarkers, Tumor|Cell Line, Tumor|GABRP protein, human 40 GABRP 24891455 Endocr. Relat. Cancer 2014 10.1530/ERC-13-0485 16 3 2 19 Humans|Carcinoma, Ductal, Breast|Receptors, Progesterone|Receptor, ErbB-2|Receptors, Estrogen|BRCA1 protein, human|BRCA1 Protein|Biomarkers, Tumor|GATA3 protein, human|GATA3 Transcription Factor|Hepatocyte Nuclear Factor 3-alpha|Tissue Array Analysis|miRNA|Gene Expression Profiling|*Phenotype|*Breast Neoplasms|SLC6A14 protein, human|Amino Acid Transport Systems, Neutral|GABRP protein, human 40 GABRP 24586412 PLoS ONE 2014 PMC3931645 10.1371/journal.pone.0088848 14 3 1 19 Mice|Animals|*Epithelial Cells|*Signal Transduction|Neuroepithelial Bodies|*Bronchioles|Receptors, Notch|Lung|Stem Cells|*Gene Expression|In Situ Hybridization|Downregulation|Chad|Reg3g protein, mouse|Pancreatitis-Associated Proteins 40 GAGE1 25171478 Cancer Biomark 2014 10.3233/CBM-140413 2 0 0 20 Humans|Male|*Antigens, Neoplasm|*Thyroid Cancer|Autoantibodies|Biomarkers, Tumor|Early Detection of Cancer|Sensitivity and Specificity|Lung Neoplasms|*Survey 48 GIMAP4 25405820 Curr Opin Rheumatol 2014 10.1097/BOR.0000000000000124 11 1 1 68 *Vasculitis|Genetic Predisposition to Disease 29 GIMAP4 25329815 PLoS ONE 2014 PMC4201521 10.1371/journal.pone.0110294 3 8 0 68 Mice|Animals|*GTPase|T-Lymphocytes|gephyrin|Membrane Proteins|B-Lymphocytes|Cell Differentiation|Cell Survival|Lymphocyte|Apoptosis|Gimap5 protein, mouse 29 GIMAP4 25287446 Immunol. Cell Biol. 2014 PMC4355353 10.1038/icb.2014.86 12 17 2 68 Humans|*Actins|*Tubulin|T-Lymphocytes, Helper-Inducer|*Lymphocyte Activation|Cell Differentiation|Cytokines|Downregulation|Interferon-gamma|Signal Transduction|*Hematopoiesis|GTPase|Apoptosis|VMA21 protein, human|Vacuolar Proton-Translocating ATPases 29 GLDN 25372825 Acta Crystallogr F Struct Biol Commun 2014 PMC4231860 10.1107/S2053230X14020305 2 0 0 88 Rats|Animals|olfactomedin|*Crystallization|*X-Rays|*Extracellular Matrix Proteins|*Glycoproteins|gliomedin, rat|Cell Adhesion Molecules, Neuronal|*X Ray Crystallographies|NRCAM protein, human|Cell Adhesion Molecules|Ranvier's Nodes|Protein Structure, Tertiary|Nerve Growth Factors|Protein Binding 30 GLDN 25331433 J. Bacteriol. 2014 PMC4288674 10.1128/JB.02085-14 25 0 2 88 *Flavobacterium|Flavobacterium johnsoniae|Bacterial Secretion Systems|chitinase ChiA|Chitinases|Adhesins, Bacterial|Gene Expression Regulation, Bacterial|Bacterial Proteins|Chitin|Protein Transport|Porphyromonas gingivalis|*Flexibacter|Mutations|Locomotion 30 GLDN 25283719 J. Neuroimmunol. 2014 10.1016/j.jneuroim.2014.09.001 8 2 1 88 Humans|*Autoantibodies|*Polyneuropathies|CIDP|G(M1) Ganglioside|Immunoglobulin M|Immunoglobulin G|ELISA|Nerve Growth Factors|*Immune System Diseases 30 GLDN 25053267 FEMS Microbiol. Lett. 2014 10.1111/1574-6968.12543 1 0 0 88 Animals|*Flavobacterium|*Oncorhynchus mykiss|Flavobacterium psychrophilum|Flavobacteriaceae Infections|Bacterial Vaccines|Fish Diseases|Immunization|Vaccination|Antibodies, Bacterial|ELISA|Freund's Adjuvant 30 GLDN 24890784 Alcohol. Clin. Exp. Res. 2014 PMC4047192 10.1111/acer.12429 7 0 1 88 Male|Humans|*Alcoholism|*Dorsolateral Prefrontal Cortex|*Exon|Gene Expression|Oligonucleotide Array Sequence Analysis|RNA, Messenger|Frontal Cortex|Alcohol Consumption 30 GLIPR2 25435094 Int. J. Mol. Med. 2014 PMC4292761 10.3892/ijmm.2014.2011 3 4 1 52 Mice|Animals|*Diabetic Neuropathies|*Nerve, Sciatic|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Streptozotocin Diabetes|Rosiglitazone|Gene Expression|Signal Transduction|Streptozotocine 21 GLIPR2 24471790 Amyloid 2014 10.3109/13506129.2014.882304 6 3 0 52 Animals|*Phosphatidic Acids|*Amyloid Fibrils|Circular Dichroism|Membrane Proteins|Protein Conformation|Amino Acid Sequence|thioflavin T|Benzothiazoles|Protein Domain 21 glycosis 24935601 Asian Pac. J. Cancer Prev. 2014 10.7314/apjcp.2014.15.9.4085 0 0 0 0 Humans|*Fluorodeoxyglucose F18|*Positron Emission Tomography Computed Tomography|*Glycolysis|*Positron-Emission Tomography|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Radiopharmaceuticals|Multimodal Imaging|Tumor Burden|Neoplasm Staging|Tomography, X-Ray Computed|Prognosis|*Atelectasis|Retrospective Studies 21 glycosis 24835113 Immunology 2014 10.1111/imm.12321 5 1 0 0 *T-Lymphocytes|*B Cells|Lymphocyte Activation|Immunity, Cellular|Immunological Diseases|Cell Differentiation 21 glycosis 24595043 PLoS ONE 2014 PMC3942461 10.1371/journal.pone.0090732 3 7 2 0 Animals|*White spot syndrome virus 1|*Temperature|*Transcriptome Analysis|Penaeidae|Arthropod Proteins|Up-Regulation|Real Time PCR|Host-Pathogen Interactions 21 GOLGA3 24566136 Int J Mol Sci 2014 PMC3958891 10.3390/ijms15022929 4 18 0 189 Humans|*Golgi Matrix Proteins|*Receptors, Adrenergic, beta-1|*Protein Transport|Golgi Complex|Plasma Membrane|Membrane Proteins|Endoplasmic Reticulum|Autoantigens|trans Golgi Network|*Cell Movement|Protein Binding|HeLa Cells 46 GPR174 25367286 Pediatr Cardiol 2014 10.1007/s00246-014-1036-x 2 0 0 18 Child|Humans|*Syncope, Vasovagal|Tilt-Table Test|*Microarray Analysis|*Gene Expression Profiling|Case-Control Studies|Disease Susceptibility|Syncope|GPR174 protein, human|Receptors, G-Protein-Coupled 26 GPR174 25320102 J. Biochem. 2014 10.1093/jb/mvu060 5 1 0 18 lysophosphatidylserine|*Lysophospholipids|Receptors, Lysophospholipid|G-Protein-Coupled Receptors|Mast Cells|Cell Proliferation 26 GPR174 25295623 J. Clin. Endocrinol. Metab. 2014 10.1210/jc.2014-2694 4 0 0 18 Female|Male|Humans|*Addison Disease|*Genes, X-Linked|Gender Bias|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Gene Frequency|Genetic Association Studies|Alleles|Graves Disease|Genotype|Chinese|Case-Control Studies|Poland|GPR174 protein, human|Receptors, G-Protein-Coupled 26 GPR174 24891334 J. Lipid Res. 2014 PMC4173991 10.1194/jlr.R046920 28 0 1 18 Humans|lysophosphatidylglycerol|Lysophospholipids|lysophosphatidylethanolamine|sphingosine 1-phosphate|lysophosphatidylserine|lysophosphatidylinositol|Receptors, Lysophospholipid|lysophosphatidic acid|G-Protein-Coupled Receptors|Signal Transduction|Sphingosine|HEK293 Cells 26 GPR179 24790204 J. Neurosci. 2014 PMC4004817 10.1523/JNEUROSCI.4044-13.2014 29 0 1 5 Mice|Animals|metabotropic glutamate receptor 6|*Receptors, Metabotropic Glutamate|Retinal Bipolar Cells|*Signal Transduction|RGS Proteins|Retina|Receptors, G-Protein-Coupled|Electroretinography|Photoreceptors, Cone|Synapse|Membrane Proteins|GPR179 protein, mouse 25 GPR179 24715752 Mol. Vis. 2014 PMC3962728 5 2 0 5 Humans|Night blindness, congenital stationary|*Pilot Projects|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|Electroretinography|Retina|Homozygote|Phenotype|*Asian Continental Ancestry Group|*Cohort Studies|Pedigree|Mutation|Visual Acuity|Amino Acid Sequence 25 GPR179 24415894 Mol. Vis. 2014 PMC3883591 7 3 0 5 Humans|Mice|Animals|*C3H Mouse|*Transgenic Mouse|*Alleles|*Mice, Inbred C57BL|Night blindness, congenital stationary|Night Blindness|Eye Diseases, Hereditary|Genetic Diseases, X-Linked|Retinal Bipolar Cells|Myopia|Electroretinography|Retina|Vision|Receptors, G-Protein-Coupled|Mutation|Receptors, Metabotropic Glutamate|Phenotype|GPR179 protein, mouse 25 gpr34 25363403 Leuk. Lymphoma 2014 10.3109/10428194.2014.981177 3 5 0 33 Mice|Animals|*Phosphatidylinositol 3-Kinase|*Proto-Oncogene Proteins c-akt|Fusion Proteins, bcr-abl|Phosphatidylinositol 3-Kinases|*Leukemia|G-protein-coupled receptor 34|*Receptors, Lysophospholipid|Signal Transduction|Cell Transformation, Neoplastic|Phosphorylation|Cell Cycle|src Homology Domain|Cell Proliferation|Apoptosis|*Carcinogenesis 42 gpr34 25320102 J. Biochem. 2014 10.1093/jb/mvu060 5 1 0 33 lysophosphatidylserine|*Lysophospholipids|Receptors, Lysophospholipid|G-Protein-Coupled Receptors|Mast Cells|Cell Proliferation 42 gpr34 25275042 Anticancer Res. 2014 4 1 0 33 lysophosphatidylserine|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinases|lysophosphatidic acid|*Lysophospholipids|Receptors, Lysophospholipid|*Colorectal Cancer|Signal Transduction|*Chemotaxis|Cell Movement|Cell Proliferation|*Colonic Neoplasms 42 GPR85 24503482 Mol. Phylogenet. Evol. 2014 10.1016/j.ympev.2014.01.022 20 4 3 29 *Rhodopsin|*Phylogeny|HCAR3 protein, human|G-Protein-Coupled Receptors|Sequence Alignment|Evolution, Molecular|Ligands|neuromedin U 25|Neuropeptides|Signal Transduction|Software|Receptors, Nicotinic 25 GRIN3B 24814139 Psychiatry Res 2014 10.1016/j.psychres.2014.04.032 6 2 0 31 Humans|*N-Methylaspartate|*Receptors, N-Methyl-D-Aspartate|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Genetic Association Studies|Schizophrenia|Asian Continental Ancestry Group|Haplotypes|Genotype|Case-Control Studies|Nerve Tissue Proteins 21 HEG1 24689081 Mol Genet Genomic Med 2014 PMC3960060 10.1002/mgg3.60 15 1 3 40 *Hemangioma, Cavernous, Central Nervous System|KRIT1 Protein|Proto-Oncogene Proteins|Apoptosis Regulatory Proteins|Microtubule-Associated Proteins|Membrane Proteins|Mutation|*Rates, Mutation|Carrier Proteins|Genetic Testing|Pedigree|Genetic Predisposition to Disease|Exons|Mutation, Missense 37 HEG1 24643410 Stroke 2014 PMC4006321 10.1161/STROKEAHA.114.004809 5 2 3 40 Humans|Mice|Animals|*Hemangioma, Cavernous, Central Nervous System|KRIT1 protein, human|KRIT1 Protein|*Carrier Proteins|Apoptosis Regulatory Proteins|Proto-Oncogene Proteins|Membrane Proteins|Mutations|Microtubule-Associated Proteins|Central Nervous System Neoplasms|Endothelial Cells|Signal Transduction|*Heart 37 HES2 25504561 Circ Arrhythm Electrophysiol 2014 PMC5884688 10.1161/CIRCEP.114.002049 11 10 1 67 Humans|*Myocytes, Cardiac|phospholamban|*Calcium-Binding Proteins|*Pluripotent Stem Cell|Sarcoplasmic Reticulum|*Heart Ventricles|Embryonic Stem Cells|Induced Pluripotent Stem Cells|Sarcoplasmic Reticulum Calcium-Transporting ATPases|Calcium Signaling|Calcium|Cell Differentiation|Cells, Cultured 55 HES2 25248479 Curr. Top. Dev. Biol. 2014 10.1016/B978-0-12-405943-6.00007-5 29 0 7 67 Animals|Humans|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Homeodomain Proteins|Repressor Proteins|Cell Differentiation|Gene Expression Regulation, Developmental|Embryonic Stem Cells|Neurogenesis|DNA Sequence|Signal Transduction 55 HES2 24695060 Reprod. Fertil. Dev. 2014 10.1071/RD13399 5 0 0 67 Female|Mice|Animals|JAG1 protein, human|Jagged-1 Protein|*Ovarian Follicle|Receptor, Notch2|Serrate-Jagged Proteins|Receptor, Notch1|Receptors, Notch|Intercellular Signaling Peptides and Proteins|Signal Transduction|Receptor, Notch3|Calcium-Binding Proteins|Basic Helix-Loop-Helix Transcription Factors|Membrane Proteins|Homeodomain Proteins|HES2 protein, human|*Transcription Factors|*Estrous Cycle|Cell Communication 55 HES2 24564569 Stem Cells Dev. 2014 PMC4086679 10.1089/scd.2013.0509 36 0 3 67 Adult|Humans|*Myocytes, Cardiac|*Cost-Benefit Analysis|*Pluripotent Stem Cells|Induced Pluripotent Stem Cells|Cell Differentiation|*Heart Ventricles|Embryonic Stem Cells|BMP4 protein, human|Bone Morphogenetic Protein 4|Embryoid Bodies|Cell Line|Human Embryonic Stem Cell|Potential, Action|activin A|Activins 55 HES2 24403239 Cancer Med 2014 PMC3892805 10.1002/cam4.118 6 13 0 67 Thyroid cancer, medullary|thiocoraline|*Carcinoma, Neuroendocrine|*Thyroid Neoplasms|*Depsipeptides|Carcinoma, Medullary|Cell Proliferation|Signal Transduction|Cell Line, Tumor|Receptor, Notch1|Apoptosis|Gene Expression Regulation, Neoplastic|*Neurosecretory Systems|Cell Cycle Arrest|Cell Cycle|Chromogranin A|Tumor Markers|*Phenotype 55 HMG20B 25486196 Cell Cycle 2014 PMC4614378 10.4161/15384101.2014.942204 0 10 0 74 Humans|*Cytokinesis|*High Mobility Group Proteins|BRCA2 protein, human|BRCA2 Protein|*Mutation|DNA-Binding Proteins|Cell Cycle Proteins|Endosomal Sorting Complexes Required for Transport|HeLa Cells|Heterozygote 22 HMGN3 24672450 Front Behav Neurosci 2014 PMC3957683 10.3389/fnbeh.2014.00087 1 1 0 72 Animals|Mice|*Anxiety|CRF receptor type 1|Receptors, Corticotropin-Releasing Hormone|*Anxiety Disorders|*Disease Models, Animal|*Gene Expression Regulation|Interactions, Gene-Environment|Behavior, Animal|*Phenotypes|Exploratory Behavior|Alleles|HMGN3 protein, mouse|HMGN Proteins 28 HMX1 24983964 PLoS ONE 2014 PMC4077761 10.1371/journal.pone.0101152 4 0 1 76 Humans|*Congenital Microtia|*Genetic Linkage|Pedigree|Lod Score|Haplotype|Genetic Predisposition to Disease|Genotype|Genome, Human|Polymorphism, Single Nucleotide|Chinese|Phenotype|*Chromosome Structures|SLC2A9 protein, human|Glucose Transport Proteins, Facilitative 47 HMX1 24945320 PLoS ONE 2014 PMC4063770 10.1371/journal.pone.0100096 3 13 1 76 Mice|Animals|*Zebrafish|*Retina|Homeodomain Proteins|Transcription Factor|Homeobox|Exons|Gene Expression Regulation|Amino Acid Sequence 47 HMX1 24641951 Life Sci. 2014 10.1016/j.lfs.2014.03.010 17 0 0 76 *Down-Regulation|*Candidemia|miRNA|*Kidney|3' Untranslated Regions 47 HMX1 24478720 Front Physiol 2014 PMC3896894 10.3389/fphys.2014.00007 6 1 0 76 Humans|Cattle|Animals|Mice|Rats|Base Sequence|Conserved Sequence|Enhancer Elements, Genetic|DNA, Intergenic|Evolution, Molecular|Genomics|Transcription Factors|External Ear 47 HMX1 24459893 Yi Chuan 2014 10.3724/sp.j.1005.2013.01198 0 0 0 76 Mice|Animals|PAX2 Transcription Factor|PAX8 protein, human|PAX8 Transcription Factor|Homeodomain Proteins|Paired Box Transcription Factors|Ear, Inner|Gene Expression Regulation, Developmental|Ectoderm|*Organogenesis|Six4 protein, mouse|Trans-Activators|Irx4 protein, mouse|Pou4f3 protein, mouse|Transcription Factor Brn-3C|Lhx2 protein, mouse|Transcription Factors|LIM-Homeodomain Proteins 47 HMX2 25523630 BMC Evol. Biol. 2014 PMC4302572 10.1186/s12862-014-0261-5 4 1 0 20 Animals|*Echolocation|*Mammals|Chiroptera|Evolution, Molecular|*Vertebrate|Phylogeny|Dolphins|Genomes|Selection, Genetic|Adaptation, Physiological|Hearing|Gene Expression 40 HMX2 25010687 PLoS Genet. 2014 PMC4091791 10.1371/journal.pgen.1004461 48 2 8 20 Child|Humans|Longitudinal Studies|Quantitative Trait Loci|*Genome, Human|Genome-Wide Association Study|Single Nucleotide Polymorphisms|*Gene Expression|Gene Regulatory Networks|Genetic Predisposition to Disease|Gene Expression Regulation|Gene Expression Profiling|Genetic Variation|Phenotype|DNA Copy Number Variations|Transcription Factors|Genomics 40 HOOK3 24637326 J. Cell Biol. 2014 PMC3998801 10.1083/jcb.201309022 50 51 6 276 *Dyneins|*Kinesin|Ustilago|Microtubules|Microtubule-Associated Proteins|Hyphae|Endosomes|Biological Transport|Protein Transport|Fungal Proteins|*Transport Vesicles|Carrier Proteins|*Ion Transport|*Biochemical Phenomena 33 HOXA6 25365922 Nat Rev Endocrinol 2014 10.1038/nrendo.2014.185 91 0 5 56 Diabetes Mellitus, Type 2|Obesity|Cardiovascular Disease|Body Composition|Metabolic Diseases|Adipocytes|Adipose Tissue, Abdominal Subcutaneous|Risk Factors|Genes, Homeobox|Abdomen|*Phenotypes 36 HOXA6 25252870 Leukemia 2014 10.1038/leu.2014.287 6 3 0 56 Animals|IGF1 protein, human|*Insulin-Like Growth Factor I|Proteins, Homeobox|Gene Expression Regulation, Leukemic|Myeloid Ecotropic Viral Integration Site 1 Protein|Genes, Homeobox|Leukemia|Neoplasm Proteins|*Hematopoietic System|Cell Transformation, Neoplastic|Malignancies, Hematopoietic|Promoter Regions, Genetic|Gene Expression Profiling|Chromatin Immunoprecipitation|Hematopoietic Stem Cell Transplantation 36 HOXA6 24866495 Zool. Res. 2014 PMC5055547 10.11813/j.issn.0254-5853.2014.3.240 1 0 0 56 Humans|Animals|Mice|Rats|Dogs|*Tupaia|*Scandentia|Genome|Phylogeny|Amino Acid Sequence|Genes, Homeobox|Experimental Animal Model|*Locomotion 36 HOXA6 24859765 Arch. Oral Biol. 2014 10.1016/j.archoralbio.2014.05.001 9 2 0 56 *Oral Cancer|*Epigenetic Repression|Carcinoma, Squamous Cell|CpG Islands|DNA Methylation|Genes, Tumor Suppressor|Azacitidine|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Decitabine|Gene Silencing|Epigenesis, Genetic|Cell Line, Tumor|Biomarkers, Tumor|Homeo Box Genes 36 HSPB3 25352652 Hum Exp Toxicol 2014 10.1177/0960327114555927 5 0 1 1045 Pregnancy|Female|Mice|Animals|*Heat Shock Proteins|glucose-regulated proteins|HSP70 Heat-Shock Proteins|DNAJB1 protein, human|HSP40 Heat-Shock Proteins|*Teratogenesis|*Hindlimbs|Tretinoin|Forelimb|TRAP1 protein, human|HSP90 Heat-Shock Proteins|Embryonic Development|Gene Expression Regulation, Developmental|*Gene Expression|Chaperonin 60|RNA, Messenger|Abnormalities, Drug-Induced|Membrane Proteins 48 HTATSF1 24634799 PLoS Curr 2014 PMC3948689 10.1371/currents.md.faafdde4bea8df4aa7d06cd5553119a6 16 1 3 139 *Muscle Development|*Real-Time Polymerase Chain Reaction|Reference Standards|*Cell Culture|Gene Expression Profiling|Myoblasts|Gene Expression|Cells, Cultured|Cell Differentiation|*Immunologic Tests 26 hus1b 25305228 Ann Plast Surg 2014 10.1097/SAP.0000000000000364 0 0 0 18 Humans|*Cicatrix, Hypertrophic|*Keloid|*Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Wound Healing|*Disease Susceptibility 32 ICA1 25547463 Neurochem. Res. 2014 10.1007/s11064-014-1503-z 1 1 0 128 Mice|Animals|*Hyperalgesia|*Formalin|glutamate receptor ionotropic, AMPA 2|AMPA Receptor|*Autoantigens|*Injection, Subcutaneous|Mice, Knockout|Pain|*Islet Cell|Carrier Proteins|Nuclear Proteins|Cell Cycle Proteins|Horn, Dorsal|Phosphorylation|Protein Transport|*Neuroendocrine Cells 106 IGSF11 25300131 Adv Neurobiol 2014 10.1007/978-1-4614-8090-7_2 3 0 0 18 Animals|Humans|Mice|*Coxsackie Adenovirus Receptor|Cell Adhesion|Cell Adhesion Molecules|Ig C2-set Domains|Neurons 27 IGSF11 24510806 Curr Protoc Cell Biol 2014 10.1002/0471143030.cb0905s61 2 0 1 18 Animals|*Cell Adhesion Molecules|*Immunoglobulin|Cell Adhesion|FN1 protein, human|Fibronectin|Axons|KRIT1 protein, human|KRIT1 Protein 27 IGSF3 24663154 J. Anim. Sci. 2014 10.2527/jas.2013-7059 13 0 2 44 Swine|Female|Animals|Italy|*Genome-Wide Association Study|Genotype|Sus scrofa|Breeding|Genome|Phenotype|Polymorphism, Single Nucleotide|Chromosomes|IGF2 protein, human|IGF-2 20 IMPG1 25085631 Ophthalmology 2014 10.1016/j.ophtha.2014.06.028 10 0 0 26 *Vitelliform Macular Dystrophy|Bestrophins|*Mutations|Fluorescein Angiography|Coherence Tomography, Optical|Eye Proteins|Chloride Channels|Electroretinography|Visual Acuity|Pedigree|Electrooculography 29 IMPG1 24702842 C. R. Biol. 2014 10.1016/j.crvi.2013.12.001 9 0 1 26 *Prevalence|*Retinal Dystrophy|Leber Congenital Amaurosis|Retinitis Pigmentosa|Mutation|Pedigree|Macular Dystrophies|*Eye Abnormalities|Genetic Association Studies 29 INSL4 24973563 Gen. Comp. Endocrinol. 2014 10.1016/j.ygcen.2014.06.017 2 0 0 17 Animals|Female|Pregnancy|*Relaxin|*Stickleback|*Rivers|relaxin receptors|Receptors, Peptide|Receptors, G-Protein-Coupled|*Seawater|Amino Acid Sequence|*Gene Expression|Insulin|Mammals|RNA, Messenger|Signal Transduction 45 insl6 25161767 Skelet Muscle 2014 PMC4144317 10.1186/2044-5040-4-16 4 8 0 28 Animals|*Autoimmune Myositis, Experimental|Idiopathic Inflammatory Myopathies|Autoimmune Diseases|Muscle, Skeletal|Muscular Diseases|Insulins 40 insl6 24973563 Gen. Comp. Endocrinol. 2014 10.1016/j.ygcen.2014.06.017 2 0 0 28 Animals|Female|Pregnancy|*Relaxin|*Stickleback|*Rivers|relaxin receptors|Receptors, Peptide|Receptors, G-Protein-Coupled|*Seawater|Amino Acid Sequence|*Gene Expression|Insulin|Mammals|RNA, Messenger|Signal Transduction 40 insl6 24913642 Electrophoresis 2014 10.1002/elps.201400175 0 0 0 28 Male|Female|hydrogen sulfite|*DNA Methylation|Mouth Mucosa|*Sulfites|Epigenetic|*Spermatozoa|Forensic Genetics|*DNA|Semen|Sequence Analysis, DNA|Body Fluids|PCR|Genetic Markers|Saliva|*Diagnostic Tests, Routine|Vagina|High-Throughput Nucleotide Sequencing 40 IPO7 25345917 BMC Complement Altern Med 2014 PMC4226917 10.1186/1472-6882-14-420 3 6 0 322 *Caspases|*Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Caspase 3|Caspase 9|bcl-2-Associated X Protein|Apoptosis|Antineoplastic Agents, Phytogenic|Proto-Oncogene Proteins c-bcl-2|Cell Line, Tumor|Panax ginseng|Poly(ADP-ribose) Polymerases|Ribosomes|Republic of Korea 55 IPO7 25069953 Antioxid. Redox Signal. 2014 PMC4270166 10.1089/ars.2014.6056 16 1 2 322 *Cysteine|*Oxidation-Reduction|Karyopherins|*Signal Transduction|beta Karyopherins|Active Transport, Cell Nucleus|Cell Nucleus|Cytoplasm|Forkhead Transcription Factors|Disulfides 55 IPO7 25043849 Genes Chromosomes Cancer 2014 10.1002/gcc.22204 16 0 5 322 Humans|*Hodgkin Disease|Transcription Factors|Reed-Sternberg Cells|Homeodomain Proteins|Homeobox Gene|MSX1 Transcription Factor|Gene Expression Regulation, Neoplastic|B-Lymphocytes|Gene Expression Profiling|Cell Line, Tumor|Wnt Signaling Pathways|Gene Activation|FOXR2 protein, human|Forkhead Transcription Factors 55 IRX4 25286293 J Vis Exp 2014 PMC4448667 10.3791/52010 28 0 2 60 Humans|*Myocytes, Cardiac|*Flow Cytometry|Induced Pluripotent Stem Cells|*Pluripotent Stem Cells|Cell Differentiation|Embryonic Stem Cells|Cell Line|BMP4 protein, human|Bone Morphogenetic Protein 4|Troponin T|Troponin I|activin A|Activins|Biomarkers|Homeodomain Proteins|*Hematopoiesis 63 IRX4 24648383 Stem Cells 2014 PMC4123739 10.1002/stem.1703 18 42 0 60 Mice|Humans|Animals|*MAP Kinase Signaling System|*Atrial Fibrillation|*Embryonic Stem Cells|*Cell Differentiation|Cardiomyocytes|*Heart Atria|Pluripotent Stem Cells|Organogenesis|BMP2 protein, human|Bone Morphogenetic Protein 2|Cells, Cultured|Signal Transduction|sarcolipin|Muscle Proteins|Proteolipids|GREM2 protein, human|Intercellular Signaling Peptides and Proteins|Irx4 protein, mouse 63 IRX4 24519855 J. 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Physiol. 2014 PMC4206563 10.1002/jcp.24577 6 19 0 60 Humans|*Genes, Homeobox|*DNA Methylation|*Carcinoma, Squamous Cell|*Histone Code|*Mouth Neoplasms|histone H3 trimethyl Lys4|Histone|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Homeodomain Proteins|Transcription Factors|Squamous Cell Carcinoma of Head and Neck|Cell Line, Tumor|Lysine|Head and Neck Neoplasms|HOXC10 protein, human|HOXB7 protein, human 63 ISL2 25367067 Dev Neurobiol 2014 PMC4497816 10.1002/dneu.22241 3 2 0 74 Mice|Animals|Optic Tectum|Ephrins|Visual Pathways|Retina|Axons|Receptor, EphA3|Retinal Ganglion Cells|*Models, Computerized|Models, Neurological|Brain Mapping|EPHA3 protein, human|Receptor Protein-Tyrosine Kinases|Ephrin-A2 55 ISL2 24755910 PLoS ONE 2014 PMC3995853 10.1371/journal.pone.0095256 2 2 0 74 Mice|Animals|Transcription Factors|LIM-Homeodomain Proteins|DNA-Binding Proteins|LIM Domain Proteins|Cell Differentiation|Cell Lineage|*Intestinal Epithelium|Gene Expression Regulation, Developmental|Insulin-Secreting Cells|mRNA|Ldb1 protein, mouse|Ldb2 protein, mouse 55 ISL2 24647754 Brain Struct Funct 2014 PMC4409641 10.1007/s00429-014-0745-5 3 2 1 74 Mice|Animals|*Superior Colliculi|*Noradrenaline|Visual Pathways|LIM-Homeodomain Proteins|Receptor, EphA3|Retinal Ganglion Cells|Axons|Space Perception|Brain Mapping|Attention|Transcription Factors 55 ISL2 24495295 Neural Dev 2014 PMC3937143 10.1186/1749-8104-9-2 26 2 1 74 *Retinal Ganglion Cells|*Axons|Superior Colliculi|Visual Pathways|Retina|Geniculate Bodies|Dendrites|Transcription Factor 55 ISM1 25200819 Gynecol. Endocrinol. 2014 10.3109/09513590.2014.945767 5 0 0 121 Pregnancy|Female|Humans|*Granulocyte-Macrophage Colony-Stimulating Factor|*Macrophage Colony-Stimulating Factor|*Embryo Implantation|Embryo Culture Techniques|*Assisted Reproductive Technology|Embryonic Development|Embryo Transfer|Blastocyst|Embryo, Mammalian|Fertilization in Vitro|Culture Media|Placenta|Granulocytes 26 ISM1 24956034 J. Interferon Cytokine Res. 2014 PMC4186767 10.1089/jir.2013.0137 5 0 0 121 Humans|Mice|Animals|*Th17 Cells|Antigens, CD1d|Lymphocyte Activation|Natural Killer T-Cells|Killer Cells, Natural|Mice, Inbred C57BL|Interferon-gamma|*Tissues, Mucosal|isthmin protein, mouse|Proteins 26 ISM1 24810858 Oncotarget 2014 PMC4039165 10.18632/oncotarget.1913 196 13 43 121 *Stomach Neoplasms|H19 long non-coding RNA|*RNA, Long Noncoding|*Carcinogenesis|Neoplasm Invasiveness|*Genes, Tumor Suppressor|MicroRNAs|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Proliferation|Cell Movement|Cell Line, Tumor|Upregulation|Lymphatic Metastasis 26 ISM1 24675886 Cell Cycle 2014 PMC4050162 10.4161/cc.28494 4 2 1 121 Animals|Mice|Chick Embryo|Somites|Lateral Plate Mesoderm|Proteins|Gene Expression Regulation, Developmental|Thrombospondin|Amino Acid Sequence|In Situ Hybridization|Zebrafish|*Chickens|Signal Transduction|isthmin protein, mouse|isthmin protein, zebrafish 26 ISM1 24520472 Int J Fertil Steril 2014 PMC3850342 2 0 0 121 Infant, Newborn|Humans|*Sperm Injections, Intracytoplasmic|Embryo Culture Techniques|Fertilization in Vitro|Embryo Transfer|Culture Media|Blastocyst|Birth Weight|Embryo Development|*Embryo, Mammalian|Retrospective Studies 26 ITIH5 25093535 Epigenetics 2014 PMC4169021 10.4161/epi.32089 10 3 0 60 Humans|*CpG Islands|Caco-2 Cells|DNA Methylation|Promoter Regions, Genetic|*Colon Cancer|*Phenotype|Prognosis|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Proteinase Inhibitory Proteins, Secretory|*Epigenetic|Tumor Cell Lines|Genes, Tumor Suppressor|ITIH5 protein, human 37 ITM2C 25150618 J. Biotechnol. 2014 10.1016/j.jbiotec.2014.08.001 0 0 0 80 Cricetinae|Animals|CHO Cells|Cricetulus|*Proteomics|*Copper|Chromatography, Liquid|Tandem Mass Spectrometry|Lactate|Culture Media|Cell Culture Techniques|Glucose|Cell Proliferation|Antibodies, Monoclonal 27 ITM2C 24831988 PLoS ONE 2014 PMC4022677 10.1371/journal.pone.0096535 6 5 0 80 Mice|Animals|GATA3 protein, human|*GATA3 Transcription Factor|Cell Lineage|Cell Differentiation|CD4-Positive T-Lymphocytes|Membrane Proteins|Gene Expression Regulation 27 KIAA0196 25454649 J. Neurol. Sci. 2014 10.1016/j.jns.2014.10.018 5 0 1 71 *Spastic Paraplegia, Hereditary|KIAA0196 protein, human|*Proteins|Pedigree|Mutation 35 KIAA0196 24916641 Eur. J. Hum. Genet. 2014 PMC4402616 10.1038/ejhg.2014.109 6 0 1 71 Male|Child|Humans|3C syndrome|*Intellectual Disability|Comparative Genomic Hybridization|Canada|*Craniofacial Abnormalities|*Dandy-Walker Syndrome|*Abnormalities, Multiple|*Heart Septal Defects, Atrial|Congenital Heart Defects|Genes, X-Linked|Syndrome|Cerebellum|Phenotype|Pedigree|Homozygote|Cohort Studies|Austria|CCDC22 protein, human 35 KLF16 25454123 Brain Res. Bull. 2014 10.1016/j.brainresbull.2014.10.008 2 1 0 93 Animals|Mice|*Dopamine|*Ethanol|RASGRF2 protein, human|*ras Guanine Nucleotide Exchange Factors|Nucleus Accumbens|SLC6A3 protein, human|Dopamine Transporter|DRD2 protein, human|Dopamine D2 Receptor|Alcoholism|Mice, Knockout|Brain|Microdialysis|Rasgrf2 protein, mouse 26 KLF16 25262913 Addict Biol 2014 10.1111/adb.12185 15 0 1 93 Rats|Mice|Animals|*Mitragyna|mitragynine|*Secologanin Tryptamine Alkaloids|Morphine|Behavior, Addictive|Analgesics|Learning|Cognition|Southeast Asia 26 KLK15 25153383 Biol. Chem. 2014 10.1515/hsz-2013-0288 4 6 0 19 Humans|Male|*miRNA|KLK15 protein, human|*Kallikrein B'|*Prostate Cancer|*Prostate|*Disease Progression|Neoplasm Grading|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Tissue Kallikreins|Cell Line, Tumor 53 KLK15 24927162 Expert Rev. Mol. Diagn. 2014 10.1586/14737159.2014.928207 3 0 1 19 Humans|Male|*Pathology, Molecular|KLK15 protein, human|*Kallikrein|Prognosis|Biomarkers, Tumor|Prostate|Prostatic Neoplasms|Colorectal Cancers 53 KLK15 24659643 J BUON 2014 2 1 0 19 Humans|Male|KLK15 protein, human|*Kallikrein B'|Prognosis|Prostate Cancer|Biomarkers, Tumor|Gastrointestinal Cancers|miRNAs|*Gastrointestinal Tract 53 KLRC4 25405820 Curr Opin Rheumatol 2014 10.1097/BOR.0000000000000124 11 1 1 16 *Vasculitis|Genetic Predisposition to Disease 24 LACRT 25481446 J Control Release 2014 PMC4456095 10.1016/j.jconrel.2014.11.016 10 12 0 69 Humans|Animals|Mice|Rabbits|*Protein A|*Mice, Inbred NOD|*Dry Eyes|Tears|Lacrimal Gland|*Keratoconjunctivitis Sicca|Dacryoadenitis|TYRP1 protein, human|*Membrane Glycoproteins|Elastin|Peptides|Disease Models, Animal|Polymers|LACRT protein, human|Glycoproteins 27 LACRT 25034600 Invest. Ophthalmol. Vis. Sci. 2014 PMC4148924 10.1167/iovs.14-13924 9 1 3 69 Humans|*Dry Eye Disease|Tears|Keratoconjunctivitis Sicca|*Administration, Topical|Glycoprotein 27 LACRT 24942736 J. Biol. Chem. 2014 PMC4139230 10.1074/jbc.M114.570143 11 0 3 69 *Tear|Glycoproteins|SDC1 protein, human|Syndecan-1|heparanase|Glucuronidase|*Antibiotics|Amino Acid Sequence|Epithelial Cells|Peptide Fragments|*Lacerations|Anti-Infective Agents|Mass Spectrometry|Proteolysis 27 LACRT 24401093 Curr. Eye Res. 2014 PMC4371594 10.3109/02713683.2013.859275 7 18 1 69 Humans|*Benzalkonium Compounds|Preservatives, Pharmaceutical|*Epithelial Cells|Epithelium, Corneal|Prostaglandins F, Synthetic|Latanoprost|Drops, Eye|Cornea|Cells, Cultured|Cell Line|Cell Survival|Apoptosis 27 laptm5 25308334 Immunity 2014 PMC4237219 10.1016/j.immuni.2014.09.011 31 19 2 113 Mice|Animals|Graft Versus Host Disease|Lymphocyte Activation|Hematopoietic Stem Cell Transplantation|Transplantation, Homologous|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Bone Marrow Transplantation|Dendritic Cells|Mice, Inbred C57BL|*Autophagy|Atg16l1 protein, mouse|Carrier Proteins 49 laptm5 25116258 Neurol. Sci. 2014 10.1007/s10072-014-1889-z 0 0 0 113 Humans|*Computational Biology|*Parkinson Disease|*Locus Coeruleus|*Gene Expression Profiling|*Microarray Analysis|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Profile, Gene Expression|Downregulation|Up-Regulation|Signal Transduction|LAPTM5 protein, human|Membrane Proteins 49 laptm5 24638062 Immunol. Cell Biol. 2014 10.1038/icb.2014.18 4 10 1 113 Kinetics|T Cell Receptor|LAPTM5 protein, human|*Membrane Proteins|SLA protein, human|Proto-Oncogene Proteins pp60(c-src)|Adaptor Proteins, Signal Transducing|CD3 Complex|T-Lymphocytes|Lymphocyte Activation|*Cell Membrane|Proto-Oncogene Proteins c-cbl|Signal Transduction|*Lysosomes|Ubiquitination 49 laptm5 24602812 Mol. Immunol. 2014 10.1016/j.molimm.2014.01.009 3 0 0 113 Humans|Mice|Animals|*Receptor, Pre-B Cell|DNA Copy Number Variations|Surrogate Light Chains|Precursor Cells, B-Lymphoid|B-Lymphocytes|*Autoimmune Diseases|Autoimmunity|LAPTM5 protein, human|Membrane Proteins|Transductions, Signal|Cell Line|Bach2 protein, mouse|Basic-Leucine Zipper Transcription Factors 49 LARP6 25488812 Nucleic Acids Res. 2014 PMC4288179 10.1093/nar/gku1287 14 4 3 495 Humans|*mRNA|Ribonucleoproteins|RNA-Binding Proteins|Protein Binding|Amino Acid Sequence|Autoantigens|*Collagen|Binding Sites|Conserved Sequence|5' UTR|RNA Polymerase III|Models, Molecular|Molecular Chaperones|Mutation|RRM1 protein, human|Tumor Suppressor Proteins 35 LBX2 25371059 Nat Commun 2014 10.1038/ncomms6368 15 1 3 16 Animals|*T-Lymphocytes|Transcription Factor|*Wnt Pathway|beta Catenin|Wnt Proteins|DNA-Binding Proteins|Co-Repressors|Repressor Proteins|Lymphoid Enhancer-Binding Factor 1|Trans-Activators|*Catenins|Transcriptional Activation|Zebrafish Proteins|Transcription, Genetic|Transcription Factor 7-Like 2 Protein|Gene Expression Regulation|Zebrafish|Histone Deacetylases 34 LBX2 24524831 Fertil. Steril. 2014 10.1016/j.fertnstert.2013.12.054 11 3 3 16 Humans|Male|*DNA Methylation|*Alleles|*B-DNA|*Infertility, Male|CpG Islands|Oligospermia|Spermatogenesis|Spermatozoa|Fertility|PIWIL1 protein, human|Argonaute Proteins|PIWIL2 protein, human 34 LHX5 25071464 Front Neuroanat 2014 PMC4082316 10.3389/fnana.2014.00059 18 6 1 58 Animals|Mice|*Chickens|*Transcription Factors|LEF1 protein, human|*Lymphoid Enhancer-Binding Factor 1|Hippocampus|Gene Expression Regulation, Developmental|Limbic System|Entorhinal Cortex|Lhx9 protein, mouse|LIM-Homeodomain Proteins|Lhx2 protein, mouse|Lef1 protein, mouse|Lmo4 protein, mouse|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 61 LIMA1 25220418 Oncogene 2014 10.1038/onc.2014.289 16 6 4 489 Neoplasm Recurrence, Local|*Osteosarcoma|Bone Neoplasms|Matrix Attachment Region Binding Proteins|Cell Movement|Cell Proliferation|Short Hairpin RNA|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Adhesion|Transcription Factors|Neoplasm Proteins|RNA, Messenger 43 Lingo2 25514360 Am. J. Respir. Cell Mol. Biol. 2014 PMC4566043 10.1165/rcmb.2014-0198OC 13 0 2 36 Humans|*Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Genetic Predisposition to Disease|Lung|European Continental Ancestry Group|Gene Expression|Genotype 31 Lingo2 25239644 Carcinogenesis 2014 PMC4247519 10.1093/carcin/bgu203 24 1 3 36 Male|Genome-Wide Association Study|Esophageal Neoplasms|Esophageal Squamous Cell Carcinoma|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Quantitative Trait Loci|Cyclin-Dependent Kinase Inhibitor p16|Case-Control Studies|Genotype|Genes, p16|Biomarkers, Tumor|Risk Factors|Genes, cdc 31 Lingo2 25170348 J Neurodev Disord 2014 PMC4147384 10.1186/1866-1955-6-34 21 0 3 36 Humans|*DNA Copy Number Variations|*Autism Spectrum Disorder|*Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Cohort Studies 31 Lingo2 24782328 Am. J. Med. Genet. A 2014 10.1002/ajmg.a.36587 19 0 3 36 Child|Humans|Comparative Genomic Hybridization|DNA Copy Number Variations|Chromosome Aberrations|Developmental Disabilities|Intellectual Disability|*Obesity|*Cohort Studies|Abnormalities, Multiple|Phenotype|Oligonucleotide Microarray|SOCS6 protein, human|Suppressor of Cytokine Signaling Proteins|CNTNAP2 protein, human|Membrane Proteins|Nerve Tissue Proteins 31 Lingo2 24531928 Mov. Disord. 2014 10.1002/mds.25819 10 0 2 36 Adult|Humans|*Essential Tremor|*Cerebellum|Nerve Tissue Proteins|Membrane Proteins|Parkinson Disease|Polymorphism, Single Nucleotide|Genotype|LINGO1 protein, human 31 LPHN2 24622401 PLoS ONE 2014 PMC3951401 10.1371/journal.pone.0091466 11 13 3 177 *Urinary Bladder|Neoplasm Recurrence, Local|*Transcriptome Profiling|*Carcinoma, Transitional Cell|Urinary Bladder Neoplasms|Transcriptome|*Urologic Neoplasms|Sequence Analysis, RNA|Urothelium|High-Throughput Nucleotide Sequencing|Gene Expression Regulation, Neoplastic|Alternative Splicing|Exon|Microarray Analysis|Databases, Genetic|platelet-derived growth factor A|Platelet-Derived Growth Factor 29 LRIG3 25431480 Mol. Biol. Evol. 2014 PMC4441790 10.1093/molbev/msu333 44 0 9 135 Cattle|Animals|Genome-Wide Association Study|*Genome|Breeding|*Genomics|*Phenotype|Haplotype|Selection, Genetic|Allele Frequency|Single Nucleotide Polymorphism 50 LRIG3 25183430 Endocr. Relat. Cancer 2014 PMC4182143 10.1530/ERC-14-0179 17 64 3 135 *Growth Factor Receptors|Membrane Proteins|*Signal Transduction|Membrane Glycoproteins|Genes, Tumor Suppressor|Tumors 50 LRRC26 25360119 Front Physiol 2014 PMC4197896 10.3389/fphys.2014.00401 23 13 5 54 Humans|*Large-Conductance Calcium-Activated Potassium Channels|Ion Channel Gating|Membrane Potentials|Protein Subunits|Neoplasm Proteins|Potassium|Cytoplasm|HEK293 Cells|Alternative Splicing|LRRC26 protein, human 29 LRRC26 24906643 Circ. Res. 2014 PMC4119551 10.1161/CIRCRESAHA.115.303407 30 30 2 54 Male|Large-Conductance Calcium-Activated Potassium Channels|*Smooth Muscle Cells|Muscle, Smooth, Vascular|Vasoconstriction|Cerebral Arteries|Membrane Potentials|Calcium Channel|Myocyte|Protein Subunits 29 LRRC26 24639523 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC3977294 10.1073/pnas.1322123111 19 2 2 54 Animals|Large-Conductance Calcium-Activated Potassium Channels|Ion Channel Gating|Large-Conductance Calcium-Activated Potassium Channel alpha Subunits|Membrane Potentials|Protein Subunits|Allosteric Regulation|Calcium|Xenopus laevis 29 LRWD1 25170821 Adv Med Sci 2014 10.1016/j.advms.2014.07.002 0 0 0 85 Male|Humans|*Leucine|*Proteins|Microtubule Proteins|Spermatogenesis|LRWD1 protein, human 22 LSG1 25319368 Plant J. 2014 10.1111/tpj.12703 20 0 5 94 *Arabidopsis|Pre-rRNA|Arabidopsis Proteins|60S Ribosomal Subunit|Ribosomes|Cell Nucleolus|RNA, Ribosomal|Ribosomal Protein|RNA Processing, Post-Transcriptional|Gene Expression Regulation, Plant|5.8S RRNA|Nuclear Proteins|GTPase|Saccharomyces cerevisiae|Protein Binding|Protein Transport 26 LSG1 24801482 PLoS ONE 2014 PMC4011843 10.1371/journal.pone.0096374 2 0 0 94 Humans|*Genome-Wide Association Study|*Autistic Disorder|Frequencies, Allele|SNPs|Genotype|Quantitative Trait Loci|Chromosome Mapping|Genetic Predisposition to Disease|Alleles|*Aptitude|Genome, Human|Regulatory Region|DNA|*Cognition|*Chromosome Structures 26 Ly75 25436775 PLoS ONE 2014 PMC4250200 10.1371/journal.pone.0114209 2 4 0 198 Male|Female|Animals|*Zebrafish|*Autoimmunity|*Gonad|Zebrafish Proteins|Sex Differentiation|Ovaries|Testes|Germ Cell|Gene Expression Regulation, Developmental|In Situ Hybridization|Oocyte 29 Ly75 25398139 PLoS ONE 2014 PMC4232600 10.1371/journal.pone.0113233 5 1 1 198 Mice|Animals|*Quantitative Trait Loci|*Exome|*Mice, Inbred C57BL|*Obesity|Body Weight|Body Composition|Crosses, Genetic|Phenotype|*Whole Exome Sequencing|Allele|*Biological Phenomena 29 Ly75 25280001 PLoS ONE 2014 PMC4184842 10.1371/journal.pone.0109533 11 31 0 198 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|IL4 protein, human|*Interleukin-4|ZAP70 protein, human|*ZAP-70 Protein-Tyrosine Kinase|*Gene Expression|Oligonucleotide Microarrays|Gene Expression Profiling|RNA, Messenger|B Cells|Signal Transduction 29 LYAR 25092918 Nucleic Acids Res. 2014 PMC4150809 10.1093/nar/gku718 12 44 2 134 Adult|Humans|Mice|Animals|gamma-Globins|Nuclear Protein|K562 Cells|Erythroid Cells|Transcription Factors|Promoter Regions, Genetic|Histone H4|Erythroid Progenitor Cells|Chromatin Immunoprecipitation|Gene Expression Regulation|Repressor Proteins|Binding Sites|Gene Silencing|Cells, Cultured|PRMT5 protein, human|Protein-Arginine N-Methyltransferases|LYAR protein, human|DNA-Binding Proteins 32 LYAR 24990247 Mol. Cell. Biochem. 2014 10.1007/s11010-014-2128-x 7 2 1 134 Mice|Male|Animals|Proteomics|*Zinc Finger|*Ribosomes|*Cell Cycle|DNA-Binding Proteins|*Cell Proliferation|Nuclear Proteins|Testis|Polysomes|*Cytosol|mRNA|Lyar protein, mouse 32 MAGEC1 25288198 BMC Cancer 2014 PMC4195907 10.1186/1471-2407-14-748 22 2 1 33 Humans|*Carcinoma, Non-Small-Cell Lung|*Cancer Vaccines|*mRNA|*Lung Neoplasms|*Adjuvants, Immunologic|*Adjuvants, Pharmaceutic|Immunotherapy|BIRC5 protein, human|Survivin|Antineoplastic Combined Chemotherapy Protocols|Mucin-1|Combined Modality Therapy|Membrane Glycoproteins 67 MAGEC1 24896625 Immunotherapy 2014 10.2217/imt.14.24 0 0 0 33 Male|*Tumor Antigens|*Multiple Myeloma|*CD4-Positive T-Lymphocytes|Neoplasm Proteins|Immunotherapy|Gene Expression Regulation, Neoplastic|Membrane Proteins|*Gene Expression 67 MAGEC1 24842123 Oncol. Rep. 2014 10.3892/or.2014.3195 8 2 2 33 *Temozolomide|*Glioblastoma|CHI3L1 protein, human|*Chitinase-3-Like Protein 1|*Down-Regulation|Dacarbazine|DNA Modification Methylases|Antineoplastic Agents, Alkylating|DNA Repair Enzymes|Brain Neoplasms|Drug Resistance, Neoplasm|Cell Line, Tumor|STAT3 protein, human|STAT3 Transcription Factor|Xenograft Model Antitumor Assays|Tumor Suppressor Proteins|Gene Expression Regulation, Neoplastic|DNA Methylation 67 MAGEC1 24820892 Hematol Oncol 2014 10.1002/hon.2143 0 0 0 33 Male|Humans|*Multiple Myeloma|In Situ Hybridization, Fluorescence|*Testis|Antigens, Neoplasm|*Chromosomal Aberrations|Neoplasm Proteins 67 MAGEC1 24820265 Int. J. Oncol. 2014 10.3892/ijo.2014.2439 9 1 0 33 Mice|Animals|*Temozolomide|*Glioblastoma|STX-0119|Mice, Nude|Neoplasm Recurrence, Local|*Quinolines|*Oxadiazoles|STAT3 protein, human|*STAT3 Transcription Factor|Dacarbazine|DNA Modification Methylases|Brain Neoplasms|Drug Resistance, Neoplasm|Cell Line, Tumor|Xenograft Model Antitumor Assays|Gene Expression Regulation, Neoplastic|Cell Proliferation|Tumor Suppressor Proteins 67 MAP3K10 25541970 PLoS ONE 2014 PMC4277466 10.1371/journal.pone.0116169 6 9 1 161 *Colorectal Cancer|*Colon Cancer|SNPs|Genetic Predisposition to Disease|Rectal Cancer|JAK2 protein, human|Janus Kinase 2|Colon|Case-Control Studies|Phenotype|Neovascularization, Pathologic|Risk Factors|Signal Transduction 61 MAP3K10 25487919 Acta Biochim. Biophys. Sin. (Shanghai) 2014 10.1093/abbs/gmu112 10 0 2 161 Animals|Signal Transduction|Drosophila|Protein-Serine-Threonine Kinases|Drosophila Proteins|Cell Proliferation|Intracellular Signaling Peptides and Proteins|Cell Differentiation|Apoptosis|Homeostasis|Tumorigenesis|Cell Movement|Models, Biological|Lymphocytes 61 MAP9 25231439 Genes Chromosomes Cancer 2014 10.1002/gcc.22219 7 0 2 342 *Hemangiosarcoma|In Situ Hybridization, Fluorescence|Comparative Genomic Hybridization|Immunohistochemistry|Neoplasms, Radiation-Induced|Gene Amplification|Proto-Oncogene Proteins c-myc|Neoplasms, Second Primary|Biomarkers, Tumor|Skin Neoplasms|Chromosome Aberrations|Diagnosis, Differential|Interphase 26 MAP9 24876664 Dis. Markers 2014 PMC4022107 10.1155/2014/798170 6 4 0 342 *Aurora Kinase A|*Microtubule-Associated Proteins|Cell Cycle Proteins|Proto-Oncogene Proteins|Gene Expression Regulation, Neoplastic|Colorectal Neoplasms|Cell Line, Tumor|Cell Cycle Control|Apoptosis 26 MAP9 24553125 Cell Cycle 2014 PMC4013161 10.4161/cc.27944 7 21 0 342 Animals|Humans|*Zebrafish|Zebrafish Proteins|Mitotic Spindle|Mitosis|Embryo, Nonmammalian|Centrosomes|Microtubule-Associated Proteins|Microtubules|Gastrulation|Cell Cycle Proteins|Gene Expression Regulation, Developmental|Morpholinos|MAP9 protein, human 26 MATN2 25329699 J. Clin. Invest. 2014 PMC4347228 10.1172/JCI71385 8 0 0 125 Humans|Animals|Mice|*Matrilin Proteins|Experimental Autoimmune Encephalomyelitis|*Axons|Myelin-Oligodendrocyte Glycoprotein|Multiple Sclerosis|Macrophages|Mice, Knockout|Inflammation|Brain|Cells, Cultured|Adaptor Proteins, Signal Transducing|MATN2 protein, human 55 MATN2 25199881 Oncol. Rep. 2014 10.3892/or.2014.3468 27 0 4 125 Humans|Female|*Extracellular Matrix Proteins|*Ovarian Cancer|*Carcinoma, Ovarian Epithelial|Gene Chip|Drug Resistance, Neoplasm|Paclitaxel|Cisplatin|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Vincristine|Doxorubicin|Upregulation|Downregulation|POSTN protein, human|Cell Adhesion Molecules|KRT23 protein, human|Keratins, Type I 55 MATN2 24959676 Molecules 2014 PMC6271824 10.3390/molecules19068472 2 0 0 125 Humans|Mice|Animals|*Matrilin Proteins|*Proteolysis|Procollagen N-Endopeptidase|Aggrecanase-1|Aggrecanase-2|Extracellular Matrix Proteins|ADAMTS1 protein, human|ADAMTS1 Protein|ADAM Proteins|Extracellular Matrix|Cell Lines 55 METRN 24393292 CNS Neurosci Ther 2014 PMC6492994 10.1111/cns.12219 17 0 2 47 Animals|Mice|*Adipokine|*Adiposity|*Obesity|Adipocytes|Adipose Tissue|3T3-L1 Cells|Adipogenesis|Subcutaneous Fat|Insulin Resistance|Caloric Restriction|*Brain 22 MIR135B 25190111 Int. J. Oncol. 2014 10.3892/ijo.2014.2641 4 9 1 0 myocardin|*Osteosarcoma|*Nuclear Proteins|Cell Proliferation|Bone Neoplasms|Neoplasm Invasiveness|MicroRNAs|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|3' UTR|Apoptosis|*Neoplastic Processes 26 MIR135B 24662333 Clin. Gastroenterol. Hepatol. 2014 10.1016/j.cgh.2014.02.038 11 0 2 0 *RNA, Micro|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Endoscopic Ultrasound-Guided Fine Needle Aspiration|Endosonography|Pancreas|*Ultrasonography|*Endoscopy 26 MIR135B 24491411 Gynecol. Oncol. 2014 10.1016/j.ygyno.2014.01.029 23 0 6 0 Humans|Female|*MicroRNAs|*Carcinoma, Endometrioid|Endometrial Neoplasms|Gene Expression Regulation, Neoplastic|Real-Time Polymerase Chain Reaction|*Plasma 26 MLLT11 24880125 Exp. Cell Res. 2014 10.1016/j.yexcr.2014.05.013 7 7 1 143 Humans|Child|*Chaperone-Mediated Autophagy|Lysosomes|Lysosomal-Associated Membrane Protein 2|Proteolysis|HSC70 Heat-Shock Proteins|Autophagy|Molecular Chaperones|Protein Binding|Chloroquine|Starvation|*Transcription Factors 40 MLLT11 24839873 Gene Expr. Patterns 2014 10.1016/j.gep.2014.05.001 4 0 2 143 Pregnancy|Female|Humans|Central Nervous System|Peripheral Nervous System|Spinal Cord|Ganglia, Dorsal Root|Neurons|*Transcription Factors|Gene Expression Regulation, Developmental|Neural Crest Cell|Embryonic Development|*Neurogenesis|Plate, Cortical|In Situ Hybridization|RNA, Messenger|Cell Differentiation|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins 40 MORC1 25503965 Nat Commun 2014 PMC4268658 10.1038/ncomms6795 32 9 4 59 Male|Mice|Animals|*DNA Transposable Elements|*Germ Line|DNA Methylation|DNA (Cytosine-5-)-Methyltransferases|Spermatozoa|Embryo, Mammalian|Arabidopsis thaliana|*Transcription Factors|Morc1 protein, mouse|Nuclear Proteins 26 MORC1 25158004 Transl Psychiatry 2014 PMC4150246 10.1038/tp.2014.75 28 6 2 59 Humans|Animals|Rats|Mice|Adult|*Major Depressive Disorder|*Genome-Wide Association Study|Epigenesis, Genetic|*Stress, Life|Epigenetic|DNA Methylation|Brain|Cortex, Prefrontal|Blood, Cord|Phenotypes|Macaca mulatta|Morc1 protein, mouse|Nuclear Proteins 26 MORC1 24799676 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC4034193 10.1073/pnas.1406611111 23 0 2 59 Mice|Animals|*Arabidopsis|*Gene Silencing|Arabidopsis Proteins|Gene Expression Regulation, Plant|DNA Methylation|Heterochromatin|Epigenesis, Genetic|Transcription Factors|Histone|Transcription, Genetic|Adenosine Triphosphatases|Nuclear Proteins|ATPases Associated with Diverse Cellular Activities|DNA Transposable Elements|Mutation 26 MORC1 24465213 PLoS Genet. 2014 PMC3898904 10.1371/journal.pgen.1003948 53 41 7 59 *DNA Methylation|*PR-SET Domains|Arabidopsis thaliana|Arabidopsis Proteins|Gene Expression Regulation, Plant|RNA, Plant|Gene Silencing|siRNA|Histone-Lysine N-Methyltransferase|Chromosomal Proteins, Non-Histone|DNA-Binding Proteins|Transcription Factors|RNA, Double-Stranded|SUVH2 protein, Arabidopsis|DRD1 protein, Arabidopsis|DNA-Directed RNA Polymerases|SUVH9 protein, Arabidopsis 26 MORC1 24390392 Plant Physiol. 2014 PMC3912112 10.1104/pp.113.227488 5 0 0 59 *Hordeum|*Disease Resistance|*Brassica napus|*ATPases|Genome-Wide Association Study|Ascomycota|Plant Immunity|Arabidopsis|Plant Diseases|Plant Proteins|Gene Expression Regulation, Plant|Genes, Plant|Plants, Genetically Modified|Fusarium|Host-Pathogen Interactions|Amino Acid Sequence|Gene Silencing 26 MPZL2 25357997 Monoclon Antib Immunodiagn Immunother 2014 PMC4216515 10.1089/mab.2014.0030 3 0 0 144 Mice|Humans|Animals|*Thymocytes|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Cell Differentiation|Receptors, Antigen, T-Cell, alpha-beta|*Antibodies, Monoclonal|Hybridoma|IL2RA protein, human|Interleukin-2 Receptor alpha Subunit|Mice, Inbred C57BL|Cells, Stromal|Epithelial Cell|CD44 protein, human|Hyaluronan Receptors 22 MPZL2 25333574 Mol Med Rep 2014 10.3892/mmr.2014.2691 8 0 1 144 Humans|Proprotein Convertases|Serine Endopeptidases|RNA, Small Interfering|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Matrix Metalloproteinase 9|*Neoplastic Processes|Signal Transduction 22 MTX3 24881917 Rinsho Ketsueki 2014 2 0 0 133 Humans|Child|*Lymphoma, Large-Cell, Anaplastic|Japan|Methotrexate|Disease-Free Survival|Antineoplastic Combined Chemotherapy Protocols|Survival Rate|Injection, Intrathecal 21 MXRA5 24621823 Tohoku J. Exp. Med. 2014 10.1620/tjem.232.167 3 0 0 21 Humans|Male|Female|*Sedentary Behavior|*Colorectal Cancer|PIAS3 protein, human|Protein Inhibitors of Activated STAT|Cancer Biomarkers|Gene Expression Regulation, Neoplastic|Poly-ADP-Ribose Binding Proteins|Molecular Chaperones|Cell Proliferation|mRNA|Chromosomal Proteins, Non-Histone|*Colonic Neoplasms|Tumor Cells, Cultured|Transductions, Signal|Dek protein, human|Oncogene Proteins 23 MYH15 25514360 Am. J. Respir. Cell Mol. Biol. 2014 PMC4566043 10.1165/rcmb.2014-0198OC 13 0 2 40 Humans|*Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Genetic Predisposition to Disease|Lung|European Continental Ancestry Group|Gene Expression|Genotype 24 MYH15 24736300 Coron. Artery Dis. 2014 PMC4017593 10.1097/MCA.0000000000000104 8 2 1 40 Male|Female|*Polymorphism, Single Nucleotide|Coronary Circulation|Coronary Angiography|Microcirculation|Coronary Artery Disease|Coronary Vessels|Myocardial Ischemia|Blood Flow Velocity|Risk Factors 24 myo1f 25263281 Eur. J. Immunol. 2014 PMC4293287 10.1002/eji.201444698 8 18 1 128 Mice|Animals|*Antigen Presentation|*Toll-Like Receptor 4|*Myosin B|*Macrophage|Histocompatibility Antigens Class II|*Genes, MHC Class II|Dendritic Cells|CD4-Positive T-Lymphocytes|Lymphocyte Activation|Antigen|*Chemokines|Phagocytosis|Bone Marrow Cells|Antigen, CD4|Endocytosis|Ovalbumin|Cell Membrane|Cells, Cultured 25 MYO5C 25324551 J. Biol. Chem. 2014 PMC4246105 10.1074/jbc.M114.578948 26 6 6 604 *Melanosomes|RAB8A protein, human|rab GTPases|Melanocytes|TYRP1 protein, human|Membrane Glycoproteins|Protein Transport|Melanins|Oxidoreductases|Lysosome|dopachrome isomerase|Intramolecular Oxidoreductases|Cell Line|Myosins 22 MYO5C 24809456 Sci Rep 2014 PMC4014986 10.1038/srep04907 7 11 0 604 *Filaments, Actin|Myosin Type V|Subfragment-1, Myosin|F-Actin|Adenosine Diphosphate|Protein Binding|Kinetics|Adenosine Triphosphate|ATPase|Secretory Vesicle 22 MYO5C 26126179 Transl Psychiatry 2014 PMC4080317 10.1038/tp.2014.35 10 9 1 604 Humans|*Neurofibrillary Tangles|*Alzheimer Disease|amyloid beta-protein (1-42)|Amyloid beta-Peptides|*Disease Progression|tau Proteins|Brain|Peptide Fragments|GRB14 protein, human|Adaptor Proteins, Signal Transducing 22 MZB1 24888588 Genes Dev. 2014 PMC4052763 10.1101/gad.240762.114 21 4 1 35 Mice|Animals|*Immunoglobulin Heavy Chain|glucose-regulated proteins|*Membrane Proteins|*HSP70 Heat-Shock Proteins|Molecular Chaperones|Immunoglobulin mu-Chains|endoplasmin|Membrane Glycoproteins|B-Lymphocytes|Plasma Cells|Lymphopoiesis|*Endoplasmic Reticulum Stress|Integrins 25 NCAM2 25464110 Eur J Med Genet 2014 10.1016/j.ejmg.2014.11.004 8 0 2 77 Child|Humans|Animals|Genome-Wide Association Study|NCAM2 protein, human|*Neural Cell Adhesion Molecule L1|Chromosome Deletion|Developmental Disabilities|*Neurodevelopmental Disorders|Autism|Phenotypes|In Situ Hybridization, Fluorescence|Neural Cell Adhesion Molecule 71 Nfkbil1 24896147 Eur. J. Hum. Genet. 2014 PMC4326702 10.1038/ejhg.2014.104 7 0 0 46 Humans|*HIV Infections|*African Continental Ancestry Group|Haplotypes|Single Nucleotide Polymorphisms|*Peripheral Nervous System Diseases|Genetic Association Studies|Genetic Predisposition to Disease|White|Alleles|Genotypes|Tumor Necrosis Factor-alpha|Asian 67 Nfkbil1 24578538 BMJ Open 2014 PMC3939656 10.1136/bmjopen-2013-004239 5 4 0 46 Humans|*Case-Control Studies|*Leprosy|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Haplotypes|*Epistasis, Genetic|Gene Frequency|Linkage Disequilibrium|*Cytokines|*Anti-Inflammatory Agents 67 Nfkbil1 24566624 Infect. Immun. 2014 PMC3993418 10.1128/IAI.01681-13 3 0 0 46 Humans|*Major Histocompatibility Complex|Lymphotoxin|Haplotype|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Periodontitis|Alleles|Linkage Disequilibrium|Genotype|Odds Ratios|*Histocompatibility Antigens 67 NHLH1 25243493 Bipolar Disord 2014 PMC4302408 10.1111/bdi.12255 29 4 6 132 Humans|*Bipolar Disorder|*DNA Methylation|*Schizophrenia|CpG Islands|*Brain|*Gene Expression|Epigenesis, Genetic|Promoter Regions, Genetic|Genetic Predisposition to Disease|*Biochemical Phenomena|Case-Control Studies 43 NPAS1 25467980 Neuron 2014 PMC4258152 10.1016/j.neuron.2014.10.040 25 22 2 55 Mice|Animals|*Interneurons|Transcription Factors|LIM-Homeodomain Proteins|Homeodomain Proteins|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Embryo, Mammalian|Nuclear Proteins|Mice, Transgenic|Cerebral Cortex|Cell Differentiation|Cell Movement|Thyroid Nuclear Factor 1|Neurons|Action Potentials|Glutamate Decarboxylase|Basal Ganglia|Npas1 protein, mouse 35 NPAS1 25230004 Eur J Med Genet 2014 10.1016/j.ejmg.2014.08.009 3 0 0 55 Humans|Male|Cleft Lip|Cleft Palate|Chromosome Deletion|Intellectual Disability|Abnormalities, Multiple|Phenotype|Haploinsufficiency|ARHGAP35 protein, human|Repressor Proteins|Brain|NPAS1 protein, human|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors|DHX34 protein, human|RNA Helicases 35 NPAS1 24921252 PLoS ONE 2014 PMC4062345 10.1371/journal.pone.0099172 5 10 0 55 Animals|*Gadus morhua|CLOCK Proteins|Circadian Rhythm|Circadian Clocks|*Muscle, Skeletal|Photoperiod|Fish Proteins|Receptors, Cytoplasmic and Nuclear 35 Npas3 25467980 Neuron 2014 PMC4258152 10.1016/j.neuron.2014.10.040 25 22 2 39 Mice|Animals|*Interneurons|Transcription Factors|LIM-Homeodomain Proteins|Homeodomain Proteins|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Embryo, Mammalian|Nuclear Proteins|Mice, Transgenic|Cerebral Cortex|Cell Differentiation|Cell Movement|Thyroid Nuclear Factor 1|Neurons|Action Potentials|Glutamate Decarboxylase|Basal Ganglia|Npas1 protein, mouse 56 olfm1 25218043 Exp. Neurol. 2014 PMC4194240 10.1016/j.expneurol.2014.09.002 10 9 0 101 Humans|Animals|Mice|olfactomedin|glutamate receptor ionotropic, AMPA 2|*Receptors, AMPA|Evoked Potentials, Visual|Extracellular Matrix Proteins|Glycoprotein|*Smell|Glaucoma, Primary Open Angle|Retina|Retinal Ganglion Cells|Mice, Knockout|Immunoprecipitation|Transcription Factors|Olfactory Bulb|Brain|Mutation 31 olfm1 25122905 J. Neurosci. 2014 PMC4131018 10.1523/JNEUROSCI.1690-14.2014 72 0 11 101 Mice|Animals|*Hair Cells, Auditory, Outer|*Transcriptome|Inner Hair Cells|*Cochlea|*Hair Cells, Vestibular 31 olfm1 25025207 PLoS ONE 2014 PMC4099183 10.1371/journal.pone.0102483 6 42 0 101 Humans|Child|RNA-Binding Protein EWS|Proto-Oncogene Protein c-fli-1|Sarcoma, Ewing|*Sarcomas|Oncogene Proteins, Fusion|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Cell Line, Tumor|*Biomarkers|*Neural Networks, Computer 31 OLFML3 25381879 Ann. Neurol. 2014 PMC4432483 10.1002/ana.24304 99 90 7 48 Humans|Mice|Animals|*Microglia|*Superoxide Dismutase-1|Amyotrophic lateral sclerosis 1|Amyotrophic Lateral Sclerosis|Superoxide Dismutase|Mice, Transgenic|Motor Neurons|Spinal Cord|Mice, Inbred C57BL|Disease Models, Animal|Disease Progression|Cells, Cultured|MicroRNAs|SOD1 protein, human|MIRN155 microRNA, human|Mirn155 microRNA, mouse 21 OTOG 24797903 PLoS ONE 2014 PMC4010391 10.1371/journal.pone.0095151 9 11 1 16 Humans|Animals|Brachyury protein|T-Box Domain Proteins|Velo-Cardio-Facial Syndrome|*Tandem Repeat|Mutation|Phenotype|Transcription Factor|*Mammals|Sequencing, Next-Generation|Disease Models, Animal|DNA|Fetal Proteins|BMPER protein, human|Carrier Proteins|TBX1 protein, human 35 OTOG 24378291 Ear Hear 2014 PMC3999258 10.1097/AUD.0000000000000008 4 0 0 16 Humans|*Phenotypes|*Mutations|Audiometry, Pure-Tone|Audiometry, Speech|Hearing Loss, Sensorineural|Pedigree|Hearing Loss|Membrane Glycoproteins|OTOGL protein, human|Membrane Proteins 35 OTOP1 24379350 Diabetes 2014 PMC3964504 10.2337/db13-1139 13 36 0 24 Mice|Animals|*Adipose Tissue|*Obesity|*Inflammation|Insulin Resistance|Diet, High-Fat|Adipose Tissue, White|Fatty Liver|Adipocytes|Macrophages|STAT1 protein, human|STAT1 Transcription Factor|*Protective Agents|Tumor Necrosis Factor-alpha|Mice, Inbred C57BL 23 oxsr1 25131591 Essays Biochem. 2014 10.1042/bse0560125 3 0 1 594 Animals|Humans|*Parkinson Disease|alpha-Synuclein|Substantia Nigra|Dopaminergic Neurons|Dopamine|Brain|Disease Models, Animal 38 oxsr1 24643240 Int. J. Biol. Sci. 2014 PMC3957088 10.7150/ijbs.8134 17 3 5 594 *Genome-Wide Association Study|*Quantitative Trait Loci|*Phenotype|Meat|Quantitative Trait, Heritable|SNPs|*Muscle|Haplotypes|Chromosomes 38 PACRG 25359836 Microscopy (Oxf) 2014 10.1093/jmicro/dfu065 0 1 0 62 Humans|*Metallothionein|*Protein Subunits|Electron Microscopy|Microscopies, Fluorescence|Cryoultramicrotomy|Axoneme|Staining and Labeling|Green Fluorescent Proteins|Chlamydomonas reinhardtii|Flagella|HeLa Cells|Protein Transport 68 pacs2 25419710 Nat. Med. 2014 PMC4412031 10.1038/nm.3735 123 22 9 228 Animals|*Endoplasmic Reticulum|*Mitochondria|ITPR1 protein, human|Inositol 1,4,5-Trisphosphate Receptors|Mitochondrial Membranes|Calcium|*Obesity|*Liver|Calcium Signaling|Endoplasmic Reticulum Stress|Homeostasis|Insulin Resistance|Metabolic Diseases 38 PAGE4 24559171 Biochemistry 2014 PMC4198062 10.1021/bi500013w 18 19 1 57 Humans|Male|*Prostate|*Phosphorylation|*Testis|Protein Conformation|Prostatic Neoplasms|Antigens, Neoplasm|Cell Line, Tumor|*Testicular Neoplasms|Protein Kinases|PAGE4 protein, human 31 PAGE4 26317029 J Biomark 2014 PMC4437385 10.1155/2014/272683 2 0 0 57 Humans|Male|*Risk Factors|*Testis|*Colorectal Cancer|Prognosis|Lymphatic Metastasis|Biomarkers, Tumor|Liver Neoplasms|SYCP1 protein, human|Nuclear Proteins|*Neoplastic Processes|*Colonic Neoplasms|Real-Time Polymerase Chain Reaction|RNA, Messenger|PAGE4 protein, human|Antigens, Neoplasm 31 PALMD 25099915 Am. J. Primatol. 2014 10.1002/ajp.22308 8 0 2 58 Humans|Mice|Animals|*Primate|*Tandem Repeats, Short|*Promoter Regions, Genetic|*Biological Evolution|Transcription Start Site|Evolution, Molecular|Mammals|Pan troglodytes|Genes, Regulator|Gorilla gorilla|PBX2 protein, human|Proto-Oncogene Proteins|Homeodomain Proteins|GFRA2 protein, human|Glial Cell Line-Derived Neurotrophic Factor Receptors|Gfra2 protein, mouse|Palmd protein, mouse|Membrane Proteins 20 PALMD 24810057 Cell Death Dis 2014 PMC4047856 10.1038/cddis.2014.176 16 21 7 58 *Phosphorylation|*Tumor Suppressor Protein p53|Palmd protein, mouse|*DNA Damage|*Membrane Proteins|Apoptosis|Serine|Cell Nucleus|*Cell Death|Protein-Serine-Threonine Kinases|Cell Line, Tumor|Transfections 20 PARP12 25086041 J. Biol. Chem. 2014 PMC4176246 10.1074/jbc.M114.589515 28 1 4 93 Humans|*Interferon|*Protein Biosynthesis|*Inflammation|Poly(ADP-ribose) Polymerases|NF-kappa B|Transcription, Genetic|Poly (ADP-Ribose) Polymerase-1|Lipopolysaccharides|Transcriptional Activation|*Antiviral Agents|Cell Nucleus|Signal Transduction|Oxidative Stress|HeLa Cells 20 parpbp 25107462 BMC Pregnancy Childbirth 2014 PMC4137092 10.1186/1471-2393-14-263 8 0 1 100 Infant, Newborn|Pregnancy|Female|Humans|*Premature Birth|*Mental Health|Anxiety|Mothers|Depression|Stress, Psychological|Infant, Premature|Psychiatric Status Rating Scales|Anxiety Disorders|Prospective Studies 25 parpbp 24958807 Clin. Cancer Res. 2014 PMC4155001 10.1158/1078-0432.CCR-13-0275 23 18 3 100 Humans|Male|*Gene Fusions|Proto-Oncogene Proteins c-ets|Transcriptional Regulator ERG|Prostate Cancer|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Oncogene Proteins, Fusion|Transcription Factors|Trans-Activators|Ewings Sarcoma 25 pax6a 24951566 Genome Biol Evol 2014 PMC4122933 10.1093/gbe/evu135 5 1 2 0 Animals|Phylogeny|Paired Box Transcription Factors|Homeodomain Proteins|Eye Proteins|Zebrafish|Repressor Proteins|Gene Duplication|Zebrafish Proteins|PAX6 Transcription Factor|Genome|Evolution, Molecular|Conserved Sequence|Gene Expression Regulation, Developmental|Synteny|Retina 32 pax6a 24929233 Neurotoxicol Teratol 2014 PMC4120066 10.1016/j.ntt.2014.06.001 10 13 0 0 Animals|Female|Pregnancy|*Zebrafish|*Ethanol|Hedgehog Proteins|Zebrafish Proteins|Embryo, Nonmammalian|Fetal Alcohol Spectrum Disorders|Teratogens|Gene Expression Regulation, Developmental|Embryonic Development|Hindbrain|Tretinoin|Neurons|Prosencephalon|Retina|Microphthalmia 32 pdia2 25475092 J. Helminthol. 2014 10.1017/S0022149X14000807 1 0 0 61 Animals|Humans|*Trichinella spiralis|PDIA3 protein, human|*Protein Disulfide-Isomerases|Trichinellosis|Helminth Proteins|Antibodies, Helminth|Cloning, Molecular|Amino Acid Sequence|Muscle 23 PDLIM1 24662836 Oncogene 2014 PMC4175366 10.1038/onc.2014.64 14 36 2 164 *Actinin|PDLIM4 protein, human|*LIM Domain Proteins|*DNA-Binding Proteins|Transcription Factors|*Neoplastic Processes|Protein Binding|Cell Movement 43 PDZD2 25075794 Anticancer Drugs 2014 10.1097/CAD.0000000000000125 5 3 1 125 *Oxaliplatin|*Luteolin|*Peroxisome Proliferator-Activated Receptors|*Colorectal Cancers|Organic Cation-Carnitine Transporter 2|Organoplatinum Compounds|Antineoplastic Agents|*Cell Lines|Apoptosis|Organic Cation Transport Proteins|Viability, Cell|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Response Element 57 PDZRN3 25355882 J. Virol. 2014 PMC4300655 10.1128/JVI.01743-14 8 3 3 80 Humans|*Human papillomavirus 18|*Papillomavirus Infections|*Human papillomavirus 16|E6 protein, Human papillomavirus type 18|*Oncogene Proteins, Viral|E6 protein, Human papillomavirus type 16|Repressor Proteins|DNA-Binding Proteins|Proteasome|Ligase, Ubiquitin-Protein|Protein Binding|Proteolysis|Signal Transduction|Host-Pathogen Interactions 26 PDZRN3 25198863 Nat Commun 2014 10.1038/ncomms5832 11 3 2 80 Animals|*Cell Polarity|*Ubiquitin|Dishevelled Proteins|Adaptor Proteins, Signal Transducing|Wnt Proteins|Phosphoproteins|*Morphogenesis|Frizzled Receptors|Endocytosis|Wnt Signaling Pathway|Endothelial Cell|*Cell Differentiation|Gene Expression Regulation, Developmental|*Ligases 26 PGDF 25482626 Cell Adh Migr 2014 PMC4594427 10.4161/19336918.2014.972785 13 1 2 0 *Platelet Derived Growth Factor B|*Osteoblasts|*Platelet Rich Plasma|Movements, Cell|Cell Differentiation|Cells, Cultured|Growth Factors|Transforming Growth Factor beta1|Blood Platelets|Chemotaxis|Actin Cytoskeleton 49 PHLDB1 24982445 J. Cell. Sci. 2014 10.1242/jcs.155663 19 0 4 51 *Cell Migration|Adaptor Proteins, Signal Transducing|Pseudopodia|Extracellular Matrix|Integrins|Cell Membrane|Cell Line, Tumor 41 PHLDB1 24935770 Asia Pac J Clin Oncol 2014 10.1111/ajco.12211 3 0 0 51 Humans|*Glioma|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Brain Neoplasms|Asian|Genome-Wide Association Study|Alleles|Case-Control Studies|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|Ethnicity|*Chromosome Structures|Risk Factors|PHLDB1 protein, human 41 PHPT1 25450458 Int. J. Biochem. Cell Biol. 2014 10.1016/j.biocel.2014.10.009 1 2 0 62 Animals|Humans|*Proteasome Endopeptidase Complex|phosphohistidine|HeLa Cells|PHPT1 protein, human|*Phosphoric Monoester Hydrolases|*Cytoplasm|*RNA Splicing|Histidine|Phosphorylation|mRNA Decay|RNA 42 PHPT1 24523290 Mol. Biol. Cell 2014 PMC3982990 10.1091/mbc.E13-04-0180 18 31 3 62 Mice|Animals|*Phosphorylation|*Histidine|Calcium Channels|TRPV Cation Channels|Calcium|Calcium Signaling|Kidney Tubules, Distal|Nme2 protein, mouse|*Nucleoside Diphosphate Kinase B|Homeostasis|Trpv5 protein, mouse 42 PILRA 24889612 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC4066494 10.1073/pnas.1324105111 12 0 0 23 Cricetinae|Animals|*Mucin|*Receptors, Immunologic|MUC1 protein, human|*Mucin-1|Membrane Glycoproteins|*Immunoglobulins|Ligands|*Polysaccharides|Amino Acid Sequence|Glycosylation|Cricetulus|N-Acetylneuraminic Acid|Carbohydrate Conformation|Models, Molecular|*Peptides|CHO Cells 38 PILRA 24843130 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC4050567 10.1073/pnas.1320716111 6 0 1 23 Cricetinae|Animals|*N-Acetylneuraminic Acid|*Siglec|glycoprotein B, Simplexvirus|Viral Envelope Proteins|Receptors, Immunologic|Membrane Glycoproteins|Protein Binding|Herpesvirus 1, Human|Ligands|Cricetulus|CHO Cells|Mutagenesis, Site-Directed 38 PILRA 24439028 Neurobiol. Aging 2014 PMC3961547 10.1016/j.neurobiolaging.2013.12.007 20 13 1 23 Genome-Wide Association Study|*Alzheimer Disease|*Age Related Macular Degeneration|Genetic Predisposition to Disease|Allele Frequency|Polymorphism, Single Nucleotide|Genetic Variation|Phenotype|Odds Ratio 38 PIWIL3 24932571 PLoS ONE 2014 PMC4059699 10.1371/journal.pone.0099687 12 12 1 21 Humans|Female|Animals|*Carcinoma, Ovarian Epithelial|*RNA, Small Interfering|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|Argonaute Proteins|Ovary|Gene Expression Regulation, Neoplastic|DNA Methylation|Cell Line, Tumor|Up-Regulation|Germ Cell|PIWIL2 protein, human 24 PIWIL3 24440970 Cancer Biomark 2014 10.3233/CBM-130360 21 0 1 21 Female|Humans|*Carcinoma, Ovarian Epithelial|Neoplasms, Glandular and Epithelial|*Lymphatic Metastasis|Ovarian Neoplasms|Prognosis|Neoplasm Staging|Biomarkers, Tumor|Ovary|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Argonaute Proteins|Lymph Nodes|PIWIL2 protein, human 24 pkd1l1 24756726 Handb Exp Pharmacol 2014 10.1007/978-3-642-54215-2_27 22 0 1 17 Humans|Animals|polycystic kidney disease 1 protein|*TRPP Cation Channels|Polycystic Kidney, Autosomal Dominant|Ion Channel|Amino Acid Sequence|*Genes, Regulator|Signal Transduction|Ion Transport|Mutation|Cell Membrane|Phenotypes|PKD1L1 protein, human|Membrane Proteins|PKD1L3 protein, human|PKDREJ protein, human|Receptors, Cell Surface 20 pkd1l1 24585447 Genesis 2014 10.1002/dvg.22767 6 0 0 17 Mice|Animals|*Cilia|Transcription Factors|Body Patterning|Gastrula|Homeodomain Proteins|Embryogenesis|Gene Expression Regulation, Developmental|Morphogenesis|Mesoderm|*Heart|Mutation|FOXJ1 protein, mouse|Forkhead Transcription Factors 20 PLCL1 25477900 Front Genet 2014 PMC4235428 10.3389/fgene.2014.00401 34 2 3 51 Adult|Humans|Child|*Electronic Health Records|*Interleukin-13|*Interleukin-5|*Speech|*Eosinophilic Esophagitis|Genome-Wide Association Study|Phenotypes|Polymorphism, Single Nucleotide|*Language Development|*Phenomic|*Language 40 PLCL1 25163765 Pflugers Arch. 2014 10.1007/s00424-014-1592-1 3 0 1 51 Mice|Animals|Cells, Pyramidal|*Cerebral Cortex|Receptors, GABA A|Synaptic Transmission|Inhibitory Postsynaptic Potentials|Excitatory Postsynaptic Potentials|Somatosensory Cortex|*Cell Communication|Intracellular Signaling Peptides and Proteins|Adaptor Proteins, Signal Transducing|Type C Phospholipases|PRIP-1 protein, mouse|PRIP-1 phospholipase C-related protein, mouse|Carrier Proteins 40 PLCL1 24865216 PLoS ONE 2014 PMC4035314 10.1371/journal.pone.0098285 3 8 0 51 Mice|Animals|*Staphylococcus aureus|*Phospholipase B|*Protein C|*Autophagy|*Staphylococcal Infections|Phagosomes|Microtubule-Associated Proteins|Adaptor Proteins, Signal Transducing|Autophagosomes|Lysosomes|Vacuoles|Fibroblasts|*Catalysis|Type C Phospholipases 40 PLCL1 24737248 Pflugers Arch. 2014 10.1007/s00424-014-1511-5 8 0 2 51 Mice|Animals|*Receptors, GABA A|*Mice, Knockout|CABIN1 protein, human|Adaptor Proteins, Signal Transducing|Intracellular Signaling Peptides and Proteins|Calcineurin|Cells, Pyramidal|Protein Transport|GABA-A Receptor Antagonists|Type C Phospholipases|PRIP-1 protein, mouse|PRIP-1 phospholipase C-related protein, mouse|Carrier Proteins 40 PLXDC2 25535841 Elife 2014 PMC4303762 10.7554/eLife.05401 18 12 1 107 Animals|pigment epithelium-derived factor|*Serpins|enovin|*Nerve Growth Factors|NTF3 protein, human|*Eye Proteins|pigment epithelium-derived factor receptor|Receptors, Neuropeptide|Protein Binding|Binding Sites|Amino Acid Sequence|*Transcription Factors|Receptors, Cell Surface|Heparin 29 PLXDC2 25487307 Hum. Genet. 2014 PMC4291513 10.1007/s00439-014-1517-2 21 5 5 107 29 POTEE 24969553 Oncol. Rep. 2014 10.3892/or.2014.3277 16 0 2 39 Humans|Female|Chromatography, Liquid|Proteomics|Tandem Mass Spectrometry|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Prognosis|APOA1 protein, human|*ApoA-I|Cell Line, Tumor|Disease Progression 20 POU3F1 25420467 Stem Cells 2014 10.1002/stem.1899 4 2 0 285 Animals|*Zebrafish|*Transcriptome|Zebrafish Proteins|*Signal Pathways|Regeneration|*Mandible|Animals, Genetically Modified|*Jaw|Wnt11 protein, human|Wnt Proteins|Cell Differentiation|Epidermis|Extremities|Fibroblast Growth Factors|Cartilage|Cell Proliferation|foxi1 protein, zebrafish|Forkhead Transcription Factors 138 POU3F1 25243889 Pathol. Int. 2014 10.1111/pin.12198 5 2 0 285 *Small Cell Lung Carcinoma|*Transcription Factor POU|Lung Cancers|Carcinoma, Non-Small-Cell Lung|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Homeodomain Proteins|Carcinoma, Neuroendocrine|Biomarkers, Tumor|Cell Line, Tumor|SYP protein, human|Synaptophysin|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Differentiation|Nerve Tissue Proteins 138 POU3F1 25158130 Gene 2014 PMC4174680 10.1016/j.gene.2014.08.041 96 9 9 285 Humans|Swine|Animals|*Mesenchymal Stem Cells|*RNA, Micro|*mRNA|*Extracellular Vesicles|Exosomes|Sequencing, RNA|Gene Ontology|Adipose Tissue|High-Throughput RNA Sequencing|Base Sequence|Cells, Cultured|Signal Transduction|MIRN378 microRNA, human 138 PPP1R3A 25131238 Chin. Med. J. 2014 3 0 0 909 *RNA, Micro|*Lovastatin|*Myocytes, Cardiac|*Inflammation|Down-Regulation|STAT3 Transcription Factor|Lipopolysaccharides 40 PPP1R3A 24438615 Chin. Med. J. 2014 13 0 0 909 Humans|*Carcinoma, Non-Small-Cell Lung|*Squamous Cell Carcinoma|*MicroRNAs|Small Cell Lung Carcinoma|Lung Cancers|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Cell Line, Tumor|MIRN205 microRNA, human 40 PRDM8 24739539 Hypertens. Res. 2014 10.1038/hr.2014.84 5 0 1 41 Humans|Mice|Animals|*Blood Pressure|*Genome-Wide Association Study|Hypertension|*Blood Pressure Determination|Single Nucleotide Polymorphism|Genetic Loci|Genetic Predisposition to Disease|Asians|FGF5 protein, human|Fibroblast Growth Factor 5|mRNA|RNA, Small Interfering|Ethnic Groups|ANTXR2 protein, human|Receptors, Peptide|Antxr2 protein, mouse|PRDM8 protein, mouse|Histone-Lysine N-Methyltransferase 25 PRDM8 24489718 PLoS ONE 2014 PMC3906029 10.1371/journal.pone.0086356 9 15 3 41 Animals|Mice|*Neocortex|Neurons|Neurogenesis|Gene Expression Regulation, Developmental|Embryo, Mammalian|Cell Differentiation|Electroporation|Cell Movement|Histone-Lysine N-Methyltransferase|PRDM8 protein, mouse|Unc5d protein, mouse|Receptors, Cell Surface 25 PRICKLE2 25193415 Pediatr. Neurol. 2014 10.1016/j.pediatrneurol.2014.07.025 7 0 0 83 Humans|*Twins, Monozygotic|*Autistic Disorder|Chromosome 3, monosomy 3p|*Chromosome Deletion|*Chromosomes, Human, Pair 3|Comparative Genomic Hybridization|Abnormalities, Multiple|In Situ Hybridization, Fluorescence|*Chromosome Aberrations|Phenotype|Syndromes 50 PRICKLE2 24938409 Dev. Biol. 2014 PMC4114335 10.1016/j.ydbio.2014.05.020 5 19 1 83 Mice|Animals|Bardet-Biedl Syndrome 7|*Bardet-Biedl Syndrome|Zebrafish|Zebrafish Proteins|Cilia|Cell Polarity|*Phenotypes|Retinitis Pigmentosa|Polydactyly|Melanosome|Prickle2 protein, mouse|Membrane Proteins|LIM Domain Proteins 50 PRIMA1 25186736 J. Neurosci. 2014 PMC6608466 10.1523/JNEUROSCI.0329-14.2014 13 0 1 187 Mice|Rats|Animals|*Butyrylcholinesterase|*Acetylcholine|*Nicotinic Receptors|*Neuromuscular Junction|Acetylcholinesterase|Acetylcholinesterase Inhibitors|Synapses|Synaptic Transmission|Receptors, ACh|*Schwann Cells|Mice, Knockout|Collagen 67 PRIMA1 25028664 Biomed Res Int 2014 PMC4083709 10.1155/2014/717919 17 0 3 187 Humans|*Multiple Myeloma|*Tumor Suppressor Protein p53|nutlin 3|Piperazines|Imidazoles|Antineoplastic Agents|Drug Resistance, Neoplasm|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one|Bridged Bicyclo Compounds, Heterocyclic|Aza Compounds 67 PRIMA1 25006124 Blood 2014 10.1182/blood-2014-01-548800 47 9 6 187 Humans|Mice|Animals|TP53 protein, human|*Tumor Suppressor Protein p53|*Multiple Myeloma|*Reactive Oxygen Species|*p53 Genes|*Antineoplastic Agents|2-hydroxymethyl-2-methoxymethylazabicyclo(2.2.2)octan-3-one|*Quinuclidines|*Cell Death|Apoptosis|2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one|Bridged Bicyclo Compounds, Heterocyclic|TNFRSF10B protein, human|Receptors, TNF-Related Apoptosis-Inducing Ligand|*Glutathione|Cell Line, Tumor|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21 67 PRIMA1 24612677 Neurobiol. Aging 2014 10.1016/j.neurobiolaging.2014.01.147 1 3 0 187 Animals|Mice|Cricetinae|presenilin 1, mouse|*Presenilin-1|*Acetylcholinesterase|*Proline|CHO Cells|Cricetulus|Secretase|Nerve Tissue Proteins|Alzheimer Disease|Protein Binding|*Membrane|Brain|Membrane Microdomains 67 PRSS56 25357075 PLoS ONE 2014 PMC4214712 10.1371/journal.pone.0110299 9 4 0 17 Humans|Mice|Animals|*mRNA|*C57BL Mice|Microphthalmia|Retinitis Pigmentosa|Retinal Degeneration|Hyperopia|Retinal Pigment Epithelium|Homozygote|Retina|*Phototransduction|Photoreceptor Cells|Mutations|Myopia|Membrane Proteins|Serine Proteases|Vision, Ocular|Allele|PRSS56 protein, human 26 PRSS56 25335978 Invest. Ophthalmol. Vis. Sci. 2014 10.1167/iovs.14-15105 16 10 0 17 Humans|Genome-Wide Association Study|Japan|*Myopia|*Refractive Errors|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Cohort Studies|European Continental Ancestry Group 26 prune2 25392181 Cancer Epidemiol. Biomarkers Prev. 2014 10.1158/1055-9965.EPI-14-0377 0 0 1 110 Humans|Male|*mRNA|Prostate Cancer|Antigens, Neoplasm|Neoplasm Proteins|RNA, Long Noncoding|Upregulation 34 prune2 25387265 J. Clin. Endocrinol. Metab. 2014 10.1210/jc.2014-3238 18 0 0 110 *Parathyroid Neoplasms|*Whole Exome Sequencing|*DNA, Catalytic|*Mutations|Adenoma|*Transcription Factors|*Mutagenesis|Tumor Suppressor Proteins|*Genes, Regulator|*Cell Migration|Catalysis 34 prune2 24608088 PLoS ONE 2014 PMC3946485 10.1371/journal.pone.0089560 22 22 3 110 Humans|*Gain of Function Mutation|*Leukemia, Myeloid, Acute|FLT3 protein, human|*fms-Like Tyrosine Kinase 3|*Signal Transduction|STAT5A protein, human|STAT5 Transcription Factor|Tyrosine Kinase|Phosphorylation|Tandem Repeat Sequences|Mutations|Point Mutations|*Phenotypes|Apoptosis|DNA-Binding Proteins|Trans-Activators|*Prognosis|Cell Lines 34 PTOV1 25270739 Tumour Biol. 2014 10.1007/s13277-014-2662-x 4 0 0 127 Humans|Male|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|Neoplasms, Glandular and Epithelial|Kaplan-Meier Analysis|Prognosis|Immunohistochemistry|Biomarkers, Tumor|*Prostatic Neoplasms|Proportional Hazards Models|Disease Progression|Cell Line, Tumor|mRNA|Real-Time PCR, Quantitative|Multivariate Analysis|PTOV1 protein, human|Neoplasm Proteins 38 PTPRCAP 24600013 J. Virol. 2014 PMC4019091 10.1128/JVI.03099-13 3 0 0 34 Humans|*Receptors, Complement 3d|Epstein Barr Virus|B Cells|*Gene Expression|Viral Matrix Proteins|Signal Transduction|Precursor Cells, B-Lymphoid|Protein Binding|Cell Line|Lymphocyte Activation|*Biochemical Phenomena|Infections 48 PURG 25220264 Proteins 2014 10.1002/prot.24690 8 0 4 44 *Monoamine Oxidase B|*Dopamine|*Catalysis|Quantum Theory|Active Site|Noradrenaline|Models, Molecular|Serotonin|Biocatalysis|Flavins 36 PURG 24678966 J Phys Chem B 2014 10.1021/jp500795p 3 0 1 44 *Monoamine Oxidase|Active Site|*Static Electricity|Thermodynamics|Models, Molecular|Kinetics|Catalysis 36 PURG 24670003 J Phys Chem B 2014 PMC4180081 10.1021/jp501737x 27 1 1 44 Humans|*Metals|Models, Molecular|Thermodynamics|Escherichia coli|Static Electricity|Water|Cations|Glyoxalase I 36 PYHIN1 25199457 Biochem. Pharmacol. 2014 10.1016/j.bcp.2014.08.031 25 2 1 57 Humans|*Immunity, Innate|Inflammasomes|Nuclear Proteins|Phosphoproteins|DNA-Binding Proteins|Receptors, Pattern Recognition|Type I Interferons|Pyrin|DNA, Viral|Transcriptional Activation|Gene Expression Regulation|PYHIN1 protein, human 20 PYHIN1 24682156 Genome Biol Evol 2014 PMC4007548 10.1093/gbe/evu066 11 3 0 57 Humans|Animals|Natural Selection|Primates|Genetics, Population|Gorilla gorilla|Sequence Alignment|Evolution, Molecular|Phylogeny|Pan troglodytes|Biological Evolution|*Nucleic Acids|Polymorphism, Genetic|Sequence Analysis, DNA|Innate Immune Responses|Proteins|Carrier Proteins|AIM2 protein, human|DNA-Binding Proteins|PYHIN1 protein, human 20 PYHIN1 24400021 Front Genet 2014 PMC3872290 10.3389/fgene.2013.00304 3 6 0 57 Humans|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|*Sodium Potassium Chloride Symporter Inhibitors|*Ethnic Groups|*Genetic Epidemiology|*Hypertension|Blood Pressure|European Continental Ancestry Group|African Americans|Blood Pressure Determination|Genotype|Phenotypes|Systole|*Diuretics|Diastole|SPATS2L protein, human|Proteins|PYHIN1 protein, human 20 RAP1GDS1 24552806 Cell Cycle 2014 PMC3984317 10.4161/cc.27804 10 4 0 152 Humans|Mice|Animals|*Cell Cycle|*Cell Division|*Lung|Small GTPases|Guanine Nucleotide Exchange Factors|Lung Carcinoma, Non-Small-Cell|MCF-7 Cells|rhoA GTP-Binding Protein|Protein Prenylation|Cell Line, Tumor|RNAi|Signal Transduction|Tumorigenesis|Protein Binding|RNA Splicing|Lung Neoplasms 48 RAP1GDS1 24415755 J. Biol. Chem. 2014 PMC3945348 10.1074/jbc.M113.527192 16 8 0 152 *Small GTPases|*Molecular Chaperones|Protein Prenylation|Protein Binding|Amino Acid Sequence|Guanine Nucleotide Exchange Factors|Signal Transduction|Recombinant Proteins|Plasma Membrane|*Amino Acids 48 RAPGEF6 24858808 PLoS ONE 2014 PMC4032295 10.1371/journal.pone.0098253 4 0 0 96 *PDZ Domains|*Guanine Nucleotide Exchange Factor|*Phosphatidic Acid|*Microvilli|RASGRF1 protein, human|*ras-GRF1|Cell Polarity|rap GTP-Binding Proteins|ezrin|Cytoskeletal Proteins|STK11 protein, human|Protein-Serine-Threonine Kinases|Plasma Membrane|Monomeric GTP-Binding Proteins|Intestinal Mucosa 25 RAPGEF6 24491570 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.01.149 4 0 1 96 Humans|Male|Female|Animals|Mice|*Guanine Nucleotide Exchange Factor|RASGRF1 protein, human|*ras-GRF1|*Spermatogenesis|rap1 GTP-Binding Proteins|Seminiferous Tubules|Testes|Epididymis|Sperm|Infertility, Male|N-Cadherin|Germ Cells|Cell Movement|RAPGEF6 protein, human|Rapgef6 protein, mouse 25 RAX2 24499263 BMC Mol. Biol. 2014 PMC3937059 10.1186/1471-2199-15-4 5 25 0 14 Animals|*Transcription Factors|*Rhodopsin|*Xenopus laevis|Promoter Regions, Genetic|Homeodomain Proteins|Eye Proteins|Trans-Activators|Transcription, Genetic|Gene Expression Regulation|Basic-Leucine Zipper Transcription Factors|Retina 25 RHBDF1 24677489 Environ. Mol. Mutagen. 2014 PMC4082746 10.1002/em.21860 0 5 4 79 *Arsenic|*Follow-Up Studies|*DNA Methylation|*B-DNA|Bangladesh|*Epigenome|Drinking Water|*Case-Control Study|CpG Islands|Environmental Exposure|Water Pollutants, Chemical|Epigenesis, Genetic|*Skin Diseases 30 RHBDF1 24648344 Cancer Res. 2014 10.1158/0008-5472.CAN-13-1027 13 5 3 79 Humans|Breast Cancer, Familial|*Breast Neoplasms|*Hypoxia-Inducible Factor 1|*Oxygen|Cell Line, Tumor|ASC1 protein, S cerevisiae|GTP-Binding Proteins|ErbB Receptors|Cell Hypoxia|Cell Proliferation|Gene Expression Regulation, Neoplastic|Signal Transduction|Neovascularization, Pathologic|Saccharomyces cerevisiae Proteins|Adaptor Proteins, Signal Transducing|Hypoxia 30 RIMS2 24648997 Biomed Rep 2014 PMC3917086 10.3892/br.2013.101 2 0 0 81 Humans|Adolescent|*Scoliosis|*Synaptic Membranes|Haplotypes|Single Nucleotide Polymorphisms|Frequencies, Allele|*Lumbosacral Region|Genetic Predisposition to Disease|Genotype|Asian Continental Ancestry Group|Case-Control Studies|Lumbar Vertebrae|Chi-Square Distribution|*Exocytosis 35 RNF39 25126410 Cell Biosci 2014 PMC4131809 10.1186/2045-3701-4-40 1 0 0 8 Humans|*HIV-1|*Viral Load|Genome-Wide Association Study|CD4 Lymphocyte Count|HIV Infections|*Plasma|Virus Replication|*Immunologic Tests|*Cell Division|Polymorphism, Single Nucleotide|RNF39 protein, human|Immediate-Early Proteins 22 RNF39 24612962 BMC Med Genomics 2014 PMC4008305 10.1186/1755-8794-7-12 12 1 2 8 Carcinoma, Hepatocellular|*Hepatitis B virus|*Epigenomics|Liver Neoplasms|*Transcriptome|DNA Methylation|Hepatitis B|MicroRNAs|Gene Expression Regulation, Neoplastic|RNA, Messenger|Trans-Activators|Gene Expression Profiling|Promoter Regions, Genetic|Vaccination 22 RNF39 24600031 J. Immunol. 2014 10.4049/jimmunol.1302745 5 0 0 8 Humans|Animals|*Genes, MHC Class I|*Callithrix|Phylogeny|Base Sequence|Alleles|Evolution, Molecular|Amino Acid Sequence|Pseudogenes|Polymorphism, Genetic|Sequence Analysis, DNA|Sequence Homology, Amino Acid|Genomics|RNF39 protein, human|Immediate-Early Proteins 22 RTTN 25305228 Ann Plast Surg 2014 10.1097/SAP.0000000000000364 0 0 0 72 Humans|*Cicatrix, Hypertrophic|*Keloid|*Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Wound Healing|*Disease Susceptibility 21 SAMSN1 25117979 Neoplasia 2014 PMC4198825 10.1016/j.neo.2014.07.002 15 9 1 51 Humans|Mice|Animals|*Multiple Myeloma|*C57BL Mice|Monoclonal Gammopathy of Undetermined Significance|Plasma Cells|SDC1 protein, human|Syndecan-1|Bone Marrow|Promoter Regions, Genetic|DNA Methylation|Stromal Cell|Genes, Tumor Suppressor|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport 25 SBSN 25283635 Cancer Sci. 2014 PMC4317965 10.1111/cas.12549 10 11 1 57 Humans|Mice|Animals|*Endothelial Cell|*Biomarkers, Tumor|Neovascularization, Pathologic|Cell Movement|Neoplasm Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Upregulation 23 SCAF1 25448681 FEBS Lett. 2014 10.1016/j.febslet.2014.10.014 4 1 0 104 *RNA Polymerase II|*Phosphorylation|RECQL5 protein, human|RecQ Helicases|Amino Acid Sequence|Saccharomyces cerevisiae Proteins|Protein Structure, Tertiary|Protein Binding|Binding Sites|Sequence Homology, Amino Acid|Set2 protein, human|Histone-Lysine N-Methyltransferase|Conserved Sequence|Models, Molecular 28 SCAMP2 25055975 Mol. Biol. Rep. 2014 10.1007/s11033-014-3599-2 0 0 1 316 Female|Pregnancy|Swine|Animals|*Genome-Wide Association Study|*SNPs|Republic of Korea|Quantitative Trait Loci|*Mammary Glands, Animal|Phenotype|Sus scrofa|Breeding|Litter Size|*Biomarkers 26 SCGB1D2 25407308 Mol. Biol. Rep. 2014 10.1007/s11033-014-3834-x 12 0 4 18 Humans|Receptor, ErbB-2|Prognosis|Biomarkers, Tumor|Immunohistochemistry|CD44 protein, human|Hyaluronan Receptors|*Epithelium|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Tissue Array Analysis|Profile, Gene Expression|GABRP protein, human|Receptors, GABA-A 156 SCGB1D2 25373323 Mol Med Rep 2014 10.3892/mmr.2014.2863 0 0 0 18 Female|Humans|ERBB2 protein, human|Receptor, ErbB-2|*Gene Expression Profiling|Prognosis|Carcinoma, Ductal, Breast|Genes, erbB-2|Receptors, Estrogen|Biomarkers, Tumor|Immunohistochemistry|Oligonucleotide Array Sequence Analysis|Profile, Gene Expression|In Situ Hybridization|Neoplasm Staging|Genes, cdc|*Breast Neoplasms|STC2 protein, human|Glycoproteins|Intercellular Signaling Peptides and Proteins 156 SCGB1D2 24603286 Arch. Biochem. Biophys. 2014 10.1016/j.abb.2014.02.012 3 3 1 18 Humans|Female|SCGB2A2 protein, human|*Mammaglobin 1|*Ovary|SCGB1D2 protein, human|*Secretoglobins|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Mammaglobin 2|Biomarkers, Tumor|Immunohistochemistry|Uteroglobin|Gene Expression Regulation, Neoplastic|mRNA|Cell Line, Tumor|Proteolipids|*Neoplastic Processes 156 SCPEP1 25446899 Cancer Cell 2014 PMC4254633 10.1016/j.ccell.2014.09.005 425 4 44 445 Humans|*Exosomes|DICER1 protein, human|Ribonuclease III|DEAD-box RNA Helicases|*Tumorigenesis|Argonaute Proteins|MicroRNAs|*Cell Transformation, Neoplastic|*Cancer|RNA-Binding Proteins|Protein Binding 47 SCPEP1 25405367 Int. J. Oncol. 2014 PMC4277250 10.3892/ijo.2014.2766 26 52 2 445 Male|*Micrococcal Nuclease|*Tudor Domain|*Cell Transformation, Neoplastic|Hepatocellular Carcinomas|*Oncogenesis|Liver Neoplasms|Gene Expression Regulation, Neoplastic|RNA-Induced Silencing Complex|Nuclear Proteins|Endonucleases|Glioma, Malignant|RNAi|Cell Nucleus 47 SCRN1 25399950 Sci Rep 2014 PMC5382666 10.1038/srep07080 8 3 2 65 Humans|*Stomach Neoplasms|Case-Control Studies|3' Untranslated Regions|Single Nucleotide Polymorphisms|*Binding Site|*Prognosis|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|MicroRNAs|Allele|Stomach|Risk Factors|Real-Time Polymerase Chain Reaction|SCRN1 protein, human|Nerve Tissue Proteins 21 SCRN1 24378410 J. Clin. Oncol. 2014 PMC3918538 10.1200/JCO.2013.50.6337 64 1 7 65 *Leukemia, Myeloid, Acute|Prognosis|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|MicroRNAs|Disease-Free Survival|Biomarkers, Tumor|*Epigenesis, Genetic|Mutation|Antineoplastic Combined Chemotherapy Protocols 21 SERPINB7 25029323 J. Invest. Dermatol. 2014 10.1038/jid.2014.156 1 0 1 30 Humans|*Protease Inhibitor|*Palmoplantar Keratosis|*Asian|Founder Effect|Mutation|Serpins|*Hand Deformities|*Foot Deformities|*Enzyme Inhibitors|Asia|Japan|SERPINB7 protein, human 57 SERPINB7 25007157 J. Recept. Signal Transduct. Res. 2014 10.3109/10799893.2014.936461 1 0 0 30 Humans|*Glomerulonephritis, IGA|Asians|Genetic Predisposition to Disease|Allele|Genotype|Polymorphism, Single Nucleotide|Haplotypes|Serpins|Disease Progression|China 57 SERPINB7 24954659 Am. J. Obstet. Gynecol. 2014 PMC4254341 10.1016/j.ajog.2014.06.035 6 0 2 30 Pregnancy|Infant, Newborn|Humans|Female|*Premature Birth|Proteomics|*Serpins|Obstetric Labor, Premature|Biomarkers|Mass Spectrometry|Case-Control Studies|Risk Factors 57 SERPINB7 24773080 Br. J. Dermatol. 2014 10.1111/bjd.13076 2 0 1 30 *Palmoplantar Keratosis|*Pattern, Inheritance|Mutations|Serpins|*Hand Deformities|*Foot Deformities 57 SERPINB7 24575807 Ren Fail 2014 10.3109/0886022X.2014.890058 2 0 1 30 Humans|*Glomerulonephritis, IGA|Asians|Allele|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|European Continental Ancestry Group|Haplotypes|Genotype|Serpins|Risk Factor|Disease Progression 57 SERPINI1 25401298 Nat. Genet. 2014 PMC4281260 10.1038/ng.3144 64 0 11 165 Humans|*Progressive Myoclonus Epilepsy|Shaw Potassium Channels|Ataxia|Seizures, Tonic-Clonic|Mutation|Pedigree|Base Sequence|NHLRC1 protein, human|Carrier Proteins|EPM2A protein, human|Protein Tyrosine Phosphatases, Non-Receptor|KCNC1 protein, human|TBC1D24 protein, human|Membrane Proteins|Nerve Tissue Proteins 31 SETMAR 25333365 PLoS ONE 2014 PMC4198141 10.1371/journal.pone.0109741 3 7 0 173 Humans|*Colon Cancer|Cancer Stem Cells|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|mariner transposases|*Transposase|DNA-Binding Proteins|DNA Repair|Topoisomerase II|DNA Replication|Transcription Factors|Chromosome|Cisplatin|Transposable Element|Cell Line|Genes, Homeobox 44 SETMAR 25024738 Cell Div 2014 PMC4094783 10.1186/1747-1028-9-1 4 23 1 173 *DNA Repair|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|DNA Replication|DNA Damage|DNA Breaks, Double-Stranded|Transposase|Histones|DNA-Binding Proteins|DNA|Phosphorylation|Ubiquitination 44 SETMAR 24655462 BMC Mol. Biol. 2014 PMC3998112 10.1186/1471-2199-15-6 4 6 1 173 Humans|Animals|DNA Repair|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|DNA End-Joining Repair|DNA Breaks, Double-Stranded|Recombination Repair, Homologous|DNA Damage|*Episomes|Endonucleases|*Mammals|Cell Cycle 44 SETMAR 24607956 Exp. Hematol. 2014 10.1016/j.exphem.2014.02.005 3 3 0 173 Humans|Mice|Animals|Adult|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|mariner transposases|DNA-Binding Proteins|Transposases|DNA Repair|*Hematologic Neoplasms|Leukemia, Myeloid, Acute|Chromosomal Translocation|Chromosome Aberrations 44 SETMAR 24573677 J. Biol. Chem. 2014 PMC4036204 10.1074/jbc.M113.533216 13 15 2 173 Animals|SETMAR protein, human|*Histone-Lysine N-Methyltransferase|*DNA End-Joining Repair|DNA Repair|Transposases|DNA Replication|DNA, Single-Stranded|DNA Damage|DNA|Histones|Methylation 44 SH3PXD2B 24906442 BMC Genomics 2014 PMC4102727 10.1186/1471-2164-15-442 59 5 16 105 Cattle|Animals|*Quantitative Trait Loci|Genome-Wide Association Study|*Breeding|Phenotype|Genotypes|Weights, Body|Polymorphism, Single Nucleotide 23 SHROOM2 25473003 Clin. Cancer Res. 2014 10.1158/1078-0432.CCR-13-1711 16 0 1 47 Humans|*Medulloblastoma|*Hedgehog Proteins|Cerebellar Neoplasms|Anilides|Signal Transduction|Pyridines|Antineoplastic Agents|*Molecular Targeted Therapy|Xenograft Model Antitumor Assays 26 SHROOM2 24760461 Carcinogenesis 2014 PMC4146415 10.1093/carcin/bgu092 24 0 3 47 Humans|Genome-Wide Association Study|*Quantitative Trait Loci|*Colorectal Cancer|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Linkage Disequilibrium|*Colon Cancer|Colon|Genotypes|Genome, Human|Genes, Regulator|GPR143 protein, human|Eye Proteins|Membrane Glycoproteins 26 SHROOM2 24478262 Am. J. Med. Genet. 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J. Neurol. 2014 10.1111/ene.12337 7 0 0 30 Humans|*Restless Legs Syndrome|*Case-Control Studies|Genome-Wide Association Study|Taiwan|Renal Dialysis|Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Homeodomain Proteins|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Transcription Factors|Cohort Studies|Nerve Tissue Proteins|Asian|*End Stage Renal Disease|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Neoplasm Proteins 24 SLC16A9 25187157 Ann. Rheum. Dis. 2014 10.1136/annrheumdis-2014-205877 37 0 6 89 Humans|*Uric Acid|*Gout|Genetic Loci|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|European Continental Ancestry Group|Oceanic Ancestry Group|Case-Control Studies|Organic Anion Transporters|Genotype|New Zealand 30 SLC16A9 24824278 J. Hepatol. 2014 10.1016/j.jhep.2014.05.004 2 4 0 89 Humans|peginterferon alfa-2a|*Hepatitis B Surface Antigens|adefovir|*Interferon-alpha|*Organophosphonates|*Adenine|*Polyethylene Glycols|Hepatitis B, Chronic|Hepatitis B e Antigens|Hepatitis B virus|Antiviral Agents|DNA, Viral|Drug Therapy, Combination|Carnitine 30 SLC16A9 24637121 Parkinsonism Relat. Disord. 2014 10.1016/j.parkreldis.2014.02.023 8 0 0 89 Humans|*Parkinson Disease|*Uric Acid|Disease Progression|Cohort Studies|Dementia 30 SLC16A9 24376456 Front Genet 2014 PMC3860258 10.3389/fgene.2013.00277 15 12 2 89 Humans|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|*Blood Pressure|Hypertension|*Blood Pressure Determination|SNPs|Antihypertensive Agents|Systole|Phenotype|Diastole|Allele|Risk Factor|European Continental Ancestry Group|Arteries|Alcohol Consumption|CLEC3A protein, human|Lectins, C-Type|CRIPT protein, human|Adaptor Proteins, Signal Transducing 30 SLC25A24 24430870 Mol. Biol. Cell 2014 PMC3952861 10.1091/mbc.E13-08-0502 40 29 5 148 Humans|*Mitochondria|Mitochondrial Membrane Transport Proteins|Calcium Channels|Membrane Potential, Mitochondrial|Mitochondrial Proteins|Calcium|Calcium-Binding Proteins|Inner Mitochondrial Membrane|RNA Interference|Cation Transport Proteins|Short Hairpin RNA|periodate-oxidized adenosine 5'-triphosphate|Adenosine Triphosphate|*Oxidative Stress|*Cell Death|HeLa Cells|*Biological Transport|Signal Transduction 27 SLC25A24 24419621 Acta Crystallogr F Struct Biol Commun 2014 PMC3943107 10.1107/S2053230X1303241X 2 0 1 148 Humans|*Calmodulin|*X-Ray Diffraction|*Crystallization|ATP-Mg-Pi carrier proteins, mitochondria|*Mitochondrial Proteins|*Antiporters|*Mitochondria|Mitochondrial Membranes|Crystallography, X-Ray|Calcium-Binding Proteins|Protein Structure, Tertiary|Amino Acid Sequence|periodate-oxidized adenosine 5'-triphosphate|Adenosine Triphosphate 27 SLC31A2 24972308 J. Urol. 2014 10.1016/j.juro.2014.06.070 20 0 5 125 Humans|Adult|*Carcinoma, Renal Cell|Kidney Neoplasms|*Stem Cell|Kidney|AC133 Antigen 28 SLC31A2 24745988 Curr Top Membr 2014 10.1016/B978-0-12-800223-0.00009-8 11 6 1 125 *Zinc|*Copper|Cation Transport Proteins|Biological Transport|zinc-binding protein|Homeostasis|Ion Transport|Secretory Vesicles|Lysosome|Insulin 28 SLC31A2 24703712 J Trace Elem Med Biol 2014 PMC4175275 10.1016/j.jtemb.2014.03.006 13 9 1 125 Animals|*Copper|*Platinum|Cation Transport Proteins|Cisplatin|*Homeostasis|*Mammals|Biological Transport|Amino Acid Sequence|SLC31 Proteins|Copper Transporter 1 28 SLC31A2 24522273 Metallomics 2014 PMC3982597 10.1039/c3mt00331k 20 17 1 125 Humans|Mice|Animals|Female|*Cisplatin|*Copper|ATP7A protein, human|Copper-Transporting ATPases|Antineoplastic Agents|Cation Transport Proteins|Drug Resistance, Neoplasm|Ovarian Neoplasms|*Cytoplasm|Biological Transport 28 SMPDL3B 25126087 Front Endocrinol (Lausanne) 2014 PMC4115628 10.3389/fendo.2014.00127 19 23 3 44 Humans|*Podocytes|*Sphingolipids|Focal Segmental Glomerulosclerosis|Kidney Glomerulus|Sphingomyelin Phosphodiesterase|Proteinuria|Diabetic Kidney Disease|Ceramides|Signal Transduction|Membrane Microdomains|Glomerular Filtration Barrier 23 SMPDL3B 24925721 J. Am. Soc. Nephrol. 2014 PMC4279736 10.1681/ASN.2013111213 39 1 3 44 Humans|*Podocytes|*Sphingomyelin Phosphodiesterase|*Cyclic Nucleotide Phosphodiesterases, Type 3|PLAUR protein, human|Receptor, Urokinase Plasminogen Activator|Glomerulosclerosis, Focal Segmental|Proteinuria|Diabetic Kidney Disease|Signal Transduction|*Phenotypes|Serum 23 SMPDL3B 24861084 Nat Rev Nephrol 2014 PMC4386893 10.1038/nrneph.2014.87 32 19 3 44 Humans|*Podocytes|Focal Segmental Glomerulosclerosis|APOL1 protein, human|Apolipoprotein L1|Diabetic Kidney Disease|Sphingomyelin Phosphodiesterase|Phosphodiesterase 3B|Ceramides 23 SPAG16 25163742 Curr. Pharm. Des. 2014 10.2174/1381612820666140825122525 9 0 1 28 Humans|*Rheumatoid Arthritis|*Disease Progression|Synovitis|*Biomarkers|MMP3 protein, human|Matrix Metalloproteinase 3|Autoantibodies|Peptides, Cyclic|Tenosynovitis|Prognosis|Radiography|Magnetic Resonance Imaging|Bone Marrow Diseases|Cohort Studies|collagen type I trimeric cross-linked peptide|Collagen Type I|TNFSF11 protein, human|RANK Ligand 28 SPAG16 25086173 J. Immunol. 2014 10.4049/jimmunol.1401166 7 0 3 28 Humans|Animals|Mice|Male|*Multiple Sclerosis|*Autoimmunity|Experimental Autoimmune Encephalomyelitis|Oligoclonal Bands|Autoantibodies|Brain|Biomarkers|Disease Exacerbation|ELISA|Specificity|Isoelectric Focusing|Sperm 28 SPAG16 24387768 BMC Med. Genet. 2014 PMC3901032 10.1186/1471-2350-15-2 38 1 5 28 *Genome-Wide Association Study|*Bipolar Disorder|Canada|United Kingdom|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|CSMD1 protein, human|*Membrane Proteins|Nerve Tissue Proteins|Genotype|Nuclear Proteins|Cytoskeletal Proteins 28 SPOCK2 25298284 J Ovarian Res 2014 PMC4105232 10.1186/1757-2215-7-73 8 11 3 42 Humans|Female|*Endometriosis|Reproducibility of Results|*Ovarian Neoplasms|*Cell Transformation, Neoplastic|Epigenesis, Genetic|DNA Methylation|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic 35 SPOCK2 25138526 Dev. Neurosci. 2014 10.1159/000363101 4 0 0 42 Animals|Mice|*Corpus Callosum|*Axons|Neurons|Agenesis of Corpus Callosum|Brain|Cerebral Cortex|Sheaths, Myelin|Gene Expression Regulation, Developmental|Osteonectin|Anxiety 35 SPOCK2 24690998 PLoS ONE 2014 PMC3972118 10.1371/journal.pone.0093413 3 6 0 42 Humans|*Cell Transdifferentiation|*Alveolar Epithelial Cells|*Lung|Pulmonary Alveoli|Cells, Cultured|Cell Differentiation|Profile, Gene Expression|Gene Expression Profiling|Signal Transduction|Biomarkers|PLEKHO1 protein, human|Intracellular Signaling Peptides and Proteins|RAP1GAP protein, human|GTPase-Activating Proteins 35 STK17B 25178155 J. Med. Chem. 2014 10.1021/jm5007929 0 0 0 215 pyridine|Pyridines|Structure-Activity Relationship|Protein-Serine-Threonine Kinases|Protein Kinase Inhibitors|Drug Discovery|Apoptosis Regulatory Proteins|Models, Molecular|*Programmed Cell Death 1 Receptor|Apoptosis 32 STK17B 25146684 ChemMedChem 2014 10.1002/cmdc.201402234 0 0 0 215 *Pyridines|*Thiones|1,3,4-oxadiazole|*Structure-Activity Relationship|*Oxadiazoles|Protein Kinase Inhibitors|Protein-Serine-Threonine Kinases|Protein Binding|Drug Discovery|Apoptosis Regulatory Proteins 32 SVOP 24804578 J. Proteome Res. 2014 10.1021/pr500023p 3 0 1 115 Humans|*Proteome|Proteomics|*Chromosomes, Human, Pair 12|Databases, Protein|*Human Chromosome|*Glioma|Human Genome Project|Protein Annotations|Amino Acid Sequence|Mass Spectrometry|Genome, Human|Chromosome Mapping|Bioinformatics|*Neurodegenerative Disorders 26 TBPL1 25399868 Nat Commun 2014 PMC4235626 10.1038/ncomms6467 42 10 6 1191 *Lamin Type A|TERF2 protein, human|Telomeric Repeat Binding Protein 2|Hutchinson-Gilford Progeria Syndrome|Telomere|Cellular Aging|Nuclear Proteins|DNA|Fibroblasts|Mutations 28 TBPL1 24928548 Appl. Biochem. Biotechnol. 2014 10.1007/s12010-014-0947-6 3 0 0 1191 Humans|*MCF-7 Cells|stem bromelain|*Bromelains|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Antineoplastic Agents|Gene Expression Profiling|Cell Proliferation|Apoptosis|Cell Cycle Checkpoints|NOP53 protein, human|Tumor Suppressor Proteins|Genes, Regulator|Genes, cdc|Michigan|TBPL1 protein, human|TATA Box Binding Protein-Like Proteins|ARID4A protein, human 28 TBPL1 24870791 Asian Pac. J. Cancer Prev. 2014 10.7314/apjcp.2014.15.8.3767 17 3 2 1191 *Colorectal Cancer|*Genes, Tumor Suppressor|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Apoptosis|RNA, Messenger|Tumorigenesis|*Colon Cancer|Colon 28 TBX22 25373698 Hum. Genet. 2014 10.1007/s00439-014-1503-8 3 3 1 28 Humans|Male|Female|Animals|*Cleft Palate|Phylogeny|*X-Linked Gene|*Mutation|*Oncogenes|Phenotype|*Transcription Factors|*Promoter Regions, Genetic|T-Box Domain Proteins|*Binding Site|Genetic Diseases, X-Linked|Tongue Diseases|Lingual Frenum|Amino Acid Sequence|TBX22 protein, human 52 TBX22 24641171 Cleft Palate Craniofac. J. 2014 10.1597/13-151 0 0 0 28 Humans|*Chromatin|Neural Crest|Transcription Factor AP-2|Transcription Factors|*Genome Mapping|Morphogenesis|Gene Expression Regulation, Developmental|Branchio-Oculo-Facial Syndrome|Cell Differentiation|Face|Mutations|Promoter Regions, Genetic|IRF6 protein, human|Interferon Regulatory Factors 52 TBX22 24475022 PLoS ONE 2014 PMC3903472 10.1371/journal.pone.0082185 15 12 3 28 Humans|Iran|Microsatellite Instability|*Tumors, Colorectal|MutL Protein Homolog 1|DNA Methylation|Microsatellite Repeats|Nuclear Proteins|Adaptor Proteins, Signal Transducing|African Americans 52 TBX22 24458798 Am. J. Med. Genet. A 2014 10.1002/ajmg.a.36408 3 0 0 28 Humans|Female|Omodysplasia type 1|Osteochondrodysplasia|Omodysplasia 2|Dwarfism|Facies|Growth Disorders|Humerus|*Musculoskeletal Abnormalities|Abnormalities, Multiple|Metacarpal Bones|Radiography 52 tbxt 24833518 Dev. Biol. 2014 10.1016/j.ydbio.2014.05.003 7 1 1 369 Animals|*Xenopus laevis|*Wnt Signaling Pathway|Xenopus Proteins|Dishevelled Protein|*Morphogenesis|Phosphoproteins|Adaptor Proteins, Signal Transducing|Wnt Proteins|Mesoderm|Embryo, Nonmammalian|Cell Polarity|Gene Expression Regulation, Developmental|Cell Movement 75 tbxt 24611759 Dev. Growth Differ. 2014 10.1111/dgd.12122 0 0 0 369 Animals|*Xenopus laevis|Xenopus Proteins|Gastrula|*Blastocyst|Mesoderm|Fibroblast Growth Factor|Body Patterning|Signal Transduction|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Cell Movement|In Situ Hybridization 75 tbxt 24499677 BMB Rep 2014 PMC4345511 10.5483/bmbrep.2014.47.12.290 4 46 1 369 Animals|*Xenopus laevis|*Neurogenesis|Xenopus Proteins|Mesoderm|Ectoderm|T-Box Domain Proteins|Homeodomain Proteins|Fetal Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Repressor Proteins|Embryo, Nonmammalian|Nervous System|Signal Transduction|Fibroblast Growth Factors 75 TCF15 25294938 Development 2014 PMC7055718 10.1242/dev.105981 13 6 0 58 Mice|Animals|Hedgehog Proteins|*Chondrogenesis|*Somites|Glycogen Synthase Kinase 3|*Embryonic Stem Cells|Chondrocytes|Mesoderm, Paraxial|Bone Morphogenetic Proteins|Cell Differentiation|Chir 99021|Pyridines|SOX9 protein, human|SOX9 Transcription Factor|Cartilage|Pluripotent Stem Cells|Pyrimidines|Wnt Signaling Pathway|Transforming Growth Factor beta 39 TDRD3 24507716 Mol. Cell 2014 PMC3959860 10.1016/j.molcel.2014.01.011 69 19 3 132 Mice|Animals|*Chromatin|*Methylation|*Arginine|*R-Loop Structures|TOP3B protein, human|*DNA Topoisomerases, Type I|*Protein Processing, Post-Translational|Amino Acid Sequence|Genes, myc|Transcription, Genetic|Protein Binding|Transcription Factors|Supercoiled DNA 25 TENM3 25406022 Eur. J. Neurosci. 2014 10.1111/ejn.12767 12 0 0 39 Mice|Animals|*Intralaminar Thalamic Nuclei|Corpus Striatum|Visual Pathways|Neural Pathways|Neostriatum|Basal Ganglia|*Glycoprotein|Mice, Knockout 28 TENM3 24859618 Eur J Med Genet 2014 10.1016/j.ejmg.2014.05.002 53 2 1 39 *Anophthalmos|*Microphthalmos|*Coloboma|Eye Proteins|Mutation|Homeodomain Proteins|Transcription Factors|Phenotypes|SOXB1 Transcription Factors 28 TICRR 24825563 Am. J. Respir. Cell Mol. Biol. 2014 PMC4224086 10.1165/rcmb.2014-0135OC 10 0 0 110 Humans|Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|*Lung|Single Nucleotide Polymorphism|White|Genetic Predisposition to Disease|African Americans|Genetic Loci|Hispanic Americans|Ethnic Groups|TICRR protein, human|Cell Cycle Proteins 29 tiprl 24969837 Oncol. Rep. 2014 10.3892/or.2014.3279 7 2 0 1859 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Tussilago|Apoptosis|TNF-Related Apoptosis-Inducing Ligand|JNK Mitogen-Activated Protein Kinases|Hep G2 Cells|Cell Line, Tumor|Antineoplastic Agents, Phytogenic|Cell Proliferation|MAP Kinase Signaling System|Signal Transduction|Gene Expression Regulation, Neoplastic|*Cell Death 34 TLE6 25542835 Mol. Hum. Reprod. 2014 10.1093/molehr/gau116 18 0 3 17 Pregnancy|Female|Humans|Mice|Animals|Embryonic Development|Oocytes|Blastocyst|*Cytoplasm|Proteins|Gene Expression Regulation, Developmental|Amino Acid Sequence|Ovaries|Infertility, Female|Tle6 protein, human|Transcription Factors|filia protein, mouse|Ooep protein, mouse|RNA-Binding Proteins 23 TLE6 25420964 BMC Dev. Biol. 2014 PMC4247878 10.1186/s12861-014-0040-y 6 0 1 17 Sheep|Animals|Mice|*Oogenesis|Preimplantation Embryos|Oocytes|Embryonic Development|Zygote|Embryo, Mammalian|*Sheep, Domestic|Gene Expression Regulation, Developmental|Germ Cells|Cytoplasm|Amino Acid Sequence|Proteins|RNA, Messenger|filia protein, mouse|Ooep protein, mouse|RNA-Binding Proteins 23 TLE6 25208553 Nat Commun 2014 PMC6529946 10.1038/ncomms5887 22 1 4 17 Mice|Animals|*Zygote|*Actins|Embryogenesis|*Actin Cytoskeleton|Blastocyst|Oocytes|*Cytoplasm|Gene Expression Regulation, Developmental|Transcription Factors|Microfilament Proteins|filia protein, mouse|Proteins 23 TLE6 24501176 Biol. Reprod. 2014 PMC4435231 10.1095/biolreprod.113.112565 5 2 1 17 Female|Mice|Animals|*Phosphorylation|*Transducin|*Oogenesis|Meiosis|Oocytes|Metaphase|Prophase I|Cyclic AMP-Dependent Protein Kinases|Cyclic AMP|Cell Proliferation 23 TMC8 25495765 Clin. Exp. Dermatol. 2014 10.1111/ced.12506 1 0 1 65 Humans|*Epidermodysplasia Verruciformis|*Keratosis, Actinic|*Polymorphism, Genetic|Papillomaviridae|Squamous Cell Carcinoma|Mutations|Skin Neoplasms|Membrane Proteins 50 TMC8 25378492 J. Virol. 2014 PMC4300658 10.1128/JVI.02936-14 1 0 0 65 Humans|*Herpesvirus 4, Human|*Epidermodysplasia Verruciformis|Epstein Barr Virus Infection|Viral Matrix Proteins|B Cells|*Viral Proteins|Signal Transduction|NF-kappa B|*Oncogene Proteins|Cell Line|*DNA|Apoptosis 50 TMC8 25220380 Cell. Signal. 2014 10.1016/j.cellsig.2014.09.001 8 6 0 65 Humans|*Calcium|HEK293 Cells|ANO1 protein, human|Anoctamin-1|Chloride Channels|Neoplasm Proteins|Calcium Signaling|Chlorides|Endoplasmic Reticulum|Membrane Proteins|Zinc|TMC8 protein, human 50 TMEFF1 24680664 Neurochem. Int. 2014 10.1016/j.neuint.2014.03.011 1 2 0 69 Humans|Chlorocebus aethiops|Animals|Mice|Rats|Arl6ip5 protein, mouse|Carrier Proteins|Membrane Proteins|Endoplasmic Reticulum|Protein Transport|Plasma Membrane|Excitatory Amino Acid Transporter 3|Gene Expression Regulation|Protein Structure, Tertiary|Neurons|Amino Acid Sequence|Upregulation|Biotinylation|Signal Transduction|Blotting, Western|RNA, Messenger|Saccharomyces cerevisiae|COS Cells 26 TMEM135 25238935 Am. J. Pathol. 2014 PMC4188871 10.1016/j.ajpath.2014.06.025 13 0 2 40 Humans|Male|Neoplasm Recurrence, Local|*Prostate Cancer|Grading, Gleason|Prostatectomy|Prostates|Prognosis|alpha-methylacyl-CoA racemase|Racemases and Epimerases|Alpha-Methylacyl-CoA Racemase Deficiency|Disease Progression|RNA, Messenger|Lipid Metabolism, Inborn Errors 20 TMEM135 24430505 Hum. Mol. Genet. 2014 PMC4038791 10.1093/hmg/ddt675 27 0 4 40 *Calcaneus|*Genome-Wide Association Study|*Fractures, Bone|Bone Mineral Density|Osteoporosis|Single Nucleotide Polymorphisms|*Complement Factor B|Genotype|*Foot|*Ankle Injuries|Ultrasonography 20 TMEM163 25130899 Traffic 2014 PMC4205267 10.1111/tra.12205 20 3 1 9 Humans|HEK293 Cells|Mucolipidosis Type IV|Lysosomes|Transient Receptor Potential Channels|Zinc|Homeostasis|*B Cells|Proteins|Fibroblasts|TMEM163 protein, human|Membrane Proteins 22 TMEM38B 25046257 J Pediatr (Rio J) 2014 10.1016/j.jped.2014.05.003 17 0 3 37 *Osteogenesis Imperfecta|Collagen Type I|Mutation|Extracellular Matrix Proteins 25 TMEM38B 25007323 Curr. Opin. Pediatr. 2014 PMC4183132 10.1097/MOP.0000000000000117 33 29 5 37 *Osteogenesis Imperfecta|*Osteogenesis|Type I Collagen|Collagen|Genes, Recessive|Proteoglycans|*Mutations|Extracellular Matrix Proteins|Multiple Pterygium Syndrome, Autosomal Dominant|Arthrogryposis|Cyclophilins|Membrane Glycoproteins|Prolyl Hydroxylases|Protein Processing, Post-Translational 25 TMEM38B 24835313 Gene 2014 10.1016/j.gene.2014.05.028 12 0 2 37 Humans|Female|Child|*Osteogenesis Imperfecta|Homozygote|Sequence Deletion|Genes, Recessive|Exons|Collagen Type I|Pedigree|Multiple Pterygium Syndrome, Autosomal Dominant|Arthrogryposis|Phenotype|Mutation|FKBP10 protein, human|Tacrolimus Binding Proteins|TMEM38B protein, human|Ion Channels 25 TMEM70 25326274 J. Inherit. Metab. Dis. 2014 10.1007/s10545-014-9774-8 10 0 1 63 Humans|Retrospective Studies|Mitochondrial Proteins|Membrane Proteins|Mutations|Mitochondrial Proton-Translocating ATPases|Cardiomyopathy, Hypertrophic|Acidosis, Lactic|Hyperammonemia|Cell Nucleus|Turkey|Israel|Europe|TMEM70 protein, human 44 TMEM70 24757000 JIMD Rep 2014 PMC4221300 10.1007/8904_2014_309 3 0 0 63 Humans|3-Methylglutaconic Aciduria|*Leucine|3-Methylglutaconic Aciduria, Type I|*Metabolism, Inborn Errors|Costeff optic atrophy syndrome|Spastic Paraplegia, Hereditary|Optic Atrophy|Chorea|Barth Syndrome|Glutarates|Mutation 44 TMEM70 24740313 JIMD Rep 2014 PMC4270871 10.1007/8904_2014_300 2 0 1 63 Humans|Italy|oligomycin sensitivity-conferring protein|Mitochondrial Proton-Translocating ATPases|Mitochondrial Proteins|Mitochondrial Membranes|Mitochondria|Membrane Proteins|Oxidative Phosphorylation|Mutation|mtDNA|Metabolism, Inborn Errors|Cardiomyopathy|Acidosis, Lactic|Fibroblasts|Cell Nucleus|*Cohort Studies|TMEM70 protein, human 44 TONSL 25184681 Genes Dev. 2014 PMC4197947 10.1101/gad.241620.114 40 0 3 109 Humans|Female|BRCA1 protein, human|*BRCA1 Protein|*DNA Damage|DNA Repair|Transcription, Genetic|Cell Line, Tumor|Genes, Tumor Suppressor|Ovarian Cancers|Cell Nucleus|TONSL protein, human|NF-kappa B|SETX protein, human|RNA Helicases 28 tppp3 24987504 Neurol Int 2014 PMC4077210 10.4081/ni.2014.5367 6 8 0 109 Mice|Animals|Motor Neurons|Amyotrophic Lateral Sclerosis|Anterior Horn Cells|Spinal Cord|*In Situ Hybridization|*Motor Neuron Disease|*Spinal Cord Anterior Horn|*Lumbar Region|*Gene Expression|*Gray Matter|Choline Acetyltransferase|Brain 22 TSHZ1 25521865 BMC Genomics 2014 PMC4290615 10.1186/1471-2164-15-S9-S4 6 0 0 48 Horses|Animals|*Sequencing, Whole Genome|Genome|Breeding|Genetic Variation|Sequence Analysis, DNA|Polymorphism, Single Nucleotide 42 TSHZ1 24487590 J. Clin. Invest. 2014 PMC3934178 10.1172/JCI72466 16 0 2 48 Animals|Humans|*Olfactory Bulb|*Smell|*Neurogenesis|PROKR2 protein, human|Receptors, Peptide|Paired Box Transcription Factors|Neural Stem Cells|Kallmann Syndrome|Receptors, G-Protein-Coupled|Homeodomain Proteins|Eye Proteins|PAX6 Transcription Factor|Repressor Proteins|Cell Differentiation|Interneurons|Neurons|Gastrointestinal Hormones|*Gene Expression Regulation 42 TTC12 25273375 Psychopharmacology (Berl.) 2014 PMC4361268 10.1007/s00213-014-3748-2 8 1 1 11 Humans|*Tobacco Use Disorder|*Smoking|*Phenotypes|*Motivation|*Tobacco Smoking|Haplotypes|Linkage Disequilibrium|*Neural Cell Adhesion Molecules|Genetic Predisposition to Disease|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Genotype|Craving|Receptors, Dopamine D2|African Americans|Genetic Variation|Protein-Serine-Threonine Kinases|Wisconsin 24 TTI2 24794838 Structure 2014 PMC4058522 10.1016/j.str.2014.04.001 0 43 2 57 Humans|*Phosphorylation|*HSP90 Heat-Shock Proteins|Molecular Chaperones|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Transcription Factors|Nuclear Proteins|Adenosine Triphosphatases|Binding Sites|Protein Binding|AAA ATPases|Amino Acid Sequence|RPAP3 protein, human|Carrier Proteins|PIH1D1 protein, human|Apoptosis Regulatory Proteins|Tel2 protein, S cerevisiae|Telomere-Binding Proteins 25 TTI2 24657168 Mol. Cell 2014 PMC4011022 10.1016/j.molcel.2014.02.020 43 125 2 57 Humans|Mice|Animals|*Phosphorylation|*Tumor Suppressor Protein p53|*Diphosphates|*Inositol|PRKDC protein, human|*DNA-Activated Protein Kinase|Nuclear Proteins|Signal Transduction|Ataxia Telangiectasia Mutated Proteins|Cell Cycle Proteins|DNA-Binding Proteins|Tumor Suppressor Proteins|inositol hexakisphosphate kinase|Phosphotransferases (Phosphate Group Acceptor)|Apoptosis|Casein Kinase II|DNA Damage|*Cell Death 25 TWSG1 25468951 Dis Model Mech 2014 PMC4314779 10.1242/dmm.018275 5 21 0 895 Pregnancy|Female|Animals|Mice|*Holoprosencephaly|*Retinoic Acid|*Gastrulation|X-Ray Microtomography|Hedgehog Proteins|Bone Morphogenetic Protein|recombinant human bone morphogenetic protein-2|Transforming Growth Factor beta|Gene Expression Regulation, Developmental|Signal Transduction|Phenotype|Interactions, Gene-Environment|Mutation|Disease Models, Animal|Bone Morphogenetic Protein 2 47 txnl1 25348020 Curr Cancer Drug Targets 2014 10.2174/1568009614666141028094612 7 5 3 480 Humans|*Cisplatin|*Stomach Neoplasms|*Apoptosis|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Drug Resistance, Neoplasm|Antineoplastic Agents|Drug Resistance, Multiple|Cell Line, Tumor|XRCC1 protein, human|X-ray Repair Cross Complementing Protein 1|Cell Proliferation|DNA Repair|Gene Expression Regulation, Neoplastic|MicroRNAs|TXN protein, human|Thioredoxin|DNA Damage 37 txnl1 24525731 Cell Death Dis 2014 PMC3944244 10.1038/cddis.2014.27 27 32 1 480 Humans|*Cisplatin|*Stomach Neoplasms|Proteomics|*Antineoplastic Agents|XRCC1 protein, human|*XRCC1 Protein|Drug Resistance, Neoplasm|Base Excision Repair|Cell Line, Tumor|Endonucleases|DNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Apoptosis|RNA, Small Interfering|Signal Transduction|DNA Damage|*Cell Death|TXNL1 protein, human 37 UBAP2L 25185265 Blood 2014 PMC4192749 10.1182/blood-2014-01-548651 8 1 0 157 Humans|Mice|Animals|BMI1 protein, human|*Polycomb Repressive Complex 1|*Hematopoietic Stem Cell|Polycomb-Group Proteins|Proto-Oncogene Proteins|Cyclin-Dependent Kinase Inhibitor p16|Multipotent Stem Cells|Ubap2L protein, human|Carrier Proteins|Ubap2L protein, mouse 21 UBAP2L 25069639 Oncol. Rep. 2014 10.3892/or.2014.3360 7 6 0 157 Humans|Male|*Prostate|RNA Interference|*Prostate Cancer|Cell Proliferation|Gene Knockdown Techniques|RNA, Small Interfering|Cell Cycle|Cell Line, Tumor|Cell Movement|Downregulation|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Division|Carrier Proteins|Ubiquitins|Ubap2L protein, human 21 ULK4 25519392 BMC Proc 2014 PMC4143719 10.1186/1753-6561-8-S1-S57 0 0 0 17 Humans|*Haplotypes|Genome-Wide Association Study|Linkage Disequilibrium|Gene Frequency|Chromosome Mapping|Single Nucleotide Polymorphisms|Genetics, Population|*Hypertension 27 ULK4 25519342 BMC Proc 2014 PMC4143670 10.1186/1753-6561-8-S1-S72 8 2 1 17 Humans|*Blood Pressure|Blood Pressure Determination|Hypertension|Systole|Diastole|Phenotypes 27 UPK1A 25197375 Int J Clin Exp Pathol 2014 PMC4152065 1 0 0 118 Humans|*Uroplakin Ia|*Colorectal Cancer|*Disease Progression|*Colonic Neoplasms|Kaplan-Meier Estimate|Immunohistochemistry|Biomarkers, Tumor|Disease-Free Survival|Proportional Hazards Models|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Real-Time Polymerase Chain Reaction|Down-Regulation|Risk Factors 66 UPK1A 24698999 PLoS ONE 2014 PMC3974733 10.1371/journal.pone.0093073 6 6 1 118 Humans|*Uroplakin Ia|*Stomach Neoplasms|*Adenocarcinoma|Prognosis|Neoplasm Staging|Neoplasm Invasiveness|Gastric Mucosa|Lymphatic Metastasis|Biomarkers, Tumor|Cell Movement|Cell Proliferation|Real-Time Polymerase Chain Reaction|Survival Rate|Tumor Cells, Cultured|RNA, Messenger|Apoptosis|Blotting, Western|Immunoenzyme Techniques 66 UPK1A 24450554 BMC Evol. Biol. 2014 PMC3922775 10.1186/1471-2148-14-13 10 1 1 118 Animals|*Vertebrate|*Uroplakins|Evolution, Molecular|Phylogeny|Sequence Alignment|*Tetraspanins|Amino Acid Sequence|Urochordates|Base Sequence|Membrane Proteins 66 URAD 25526891 Environ. Res. 2014 10.1016/j.envres.2014.10.012 1 0 0 3 Humans|Pilot Projects|*Biological Monitoring|Environmental Exposure|Environmental Health|Environmental Monitoring|Environmental Pollutants|*Surveys|Study, Feasibility|International Cooperation|Program Development|Research Design|Risk Assessment|Europe 55 URAD 25440294 Environ. Res. 2014 10.1016/j.envres.2014.08.016 5 0 1 3 Child|Humans|Female|phthalic acid|Phthalic Acids|Mercury|Environmental Pollutants|Cotinine|Environmental Exposure|Cadmium|Hair|Environmental Monitoring|*Biomarkers|Europe|Mothers|Survey 55 URAD 24857258 Presse Med 2014 10.1016/j.lpm.2013.11.028 0 0 0 3 Humans|Female|Pregnancy|*Anesthesia, Conduction|*Nervous System Diseases|*Anesthetics|Anesthesia, Epidural|Anesthesia, General|Peripheral Nervous System Diseases|Multiple Sclerosis|Contraindications|Obstetrics 55 URAD 24787350 Anesthesiology 2014 10.1097/ALN.0000000000000276 10 0 4 3 Humans|*Tryptases|*Anaphylaxis|*Histamine|*Shock|*Anesthesia|*Arrest, Cardiac|Drug Hypersensitivity|Skin Tests|*Anesthesiology 55 URAD 24670057 Biochem. J. 2014 10.1042/BJ20140237 11 2 0 3 *Fluorescence|DAPI|inositol pentaphosphate|*Inositol Phosphates|Phytic Acid|inositol polyphosphate multikinase|Phosphotransferases (Alcohol Group Acceptor)|Phytase|Seeds|Polyphosphates|Fabaceae 55 URAD 24582108 Ann Fr Anesth Reanim 2014 10.1016/j.annfar.2013.12.023 1 0 0 3 *Pulmonary Edema|*Anesthesia, General|Tonsillectomy|Airway Obstruction|Time Factors 55 URAD 24405937 Int J Hyg Environ Health 2014 10.1016/j.ijheh.2013.12.002 11 0 3 3 Child|Female|Humans|*Biological Monitoring|*Reproducibility of Results|Mercury|phthalic acid|Phthalic Acids|Environmental Pollutants|Cotinine|Environmental Exposure|Cadmium|Hair|Environmental Monitoring|bisphenol A|Benzhydryl Compounds|Phenols|Europe|Mothers|Biomarkers|Smoking 55 USP29 25317109 Genomics Inform 2014 PMC4196374 10.5808/GI.2014.12.3.105 21 7 5 22 Humans|Animals|Mice|Genomic Imprinting|Kruppel-Like Transcription Factors|DNA Methylation|Zinc Fingers|Regulatory Sequences, Nucleic Acid|RNA, Untranslated|Ubiquitin-Specific Proteases|Evolution, Molecular|Genomics|Alleles|PEG3 protein, human|Peg3 protein, mouse|Zim1 protein, mouse|Carrier Proteins|Nerve Tissue Proteins 34 USP29 24632611 Oncogene 2014 10.1038/onc.2014.38 21 4 3 22 CLSPN protein, human|*Adaptor Proteins, Signal Transducing|DNA Replication|Checkpoint Kinase 1|Phosphorylation|Ataxia Telangiectasia Mutated Proteins|Protein Kinases|Cell Cycle Proteins|DNA Damage|Signal Transduction|Ubiquitination|Cell Cycle 34 VAX2 25096539 G3 (Bethesda) 2014 PMC4199690 10.1534/g3.114.011262 1 3 0 24 Animals|*Genome|Echolocation|Evolution, Molecular|Natural Selection|Phylogeny|Amino Acid Sequence|Pseudogenes|*Chiroptera|Genomic, Comparative|Mammals|Adaptation, Physiological|Proteins 164 VAX2 24623407 Mol. Biol. Rep. 2014 10.1007/s11033-014-3320-5 0 0 4 24 Humans|Mice|Animals|*Long Non-Coding RNA|mRNA|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Regulatory Networks|*Eye|Downregulation|*Pathological Neovascularization|Up-Regulation|Signal Transduction|Real-Time Polymerase Chain Reaction 164 VIPAS39 25239142 Ital J Pediatr 2014 PMC4422138 10.1186/s13052-014-0077-3 5 6 0 57 Arthrogryposis renal dysfunction cholestasis syndrome|*Arthrogryposis|*Cholestasis|*Renal Insufficiency|DNA Mutational Analysis|Vesicular Transport Proteins|Heterozygote|Mutations|Kidney Diseases|Phenotype|Ichthyosis|Failure to Thrive|Syndrome 24 VIPAS39 24917129 Clin. Genet. 2014 10.1111/cge.12442 2 0 0 57 Humans|Arthrogryposis renal dysfunction cholestasis syndrome|*Arthrogryposis|Renal Insufficiency|*Cholestasis|DNA Mutational Analysis|Vesicular Transport Proteins|Phenotype|Mutation|*Syndrome|VPS33B protein, human 24 VIPAS39 24782640 World J. Gastroenterol. 2014 PMC4000524 10.3748/wjg.v20.i16.4830 0 1 0 57 Humans|Female|Infant, Newborn|Arthrogryposis renal dysfunction cholestasis syndrome|*Arthrogryposis|*Cholestasis|*Renal Insufficiency|*Mutations|Vesicular Transport Proteins|Ichthyosis|Kidney|VPS33B protein, human 24 WDFY4 24549174 Int J Mol Sci 2014 PMC3958877 10.3390/ijms15022712 5 4 0 12 Humans|Female|*Chinese|*Rheumatoid Arthritis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Linkage Disequilibrium|Case-Control Studies|Lupus Erythematosus, Systemic|Autoantibodies|Homozygote|Ethnic Groups|Risk Factors|ETS1 protein, human|Proto-Oncogene Protein c-ets-1 20 WFDC1 25219356 Am. J. Pathol. 2014 PMC4215025 10.1016/j.ajpath.2014.07.013 5 1 0 69 Mice|Animals|WFDC1 protein, human|Skin|Osteopontin|Wound Healing|Cell Movement|Macrophages|mRNA|Fibroblasts|Mice, Knockout|Homeostasis 42 WHAMM 25056994 J. Dent. Res. 2014 PMC4213253 10.1177/0022034514544506 27 0 3 1784 Adult|Humans|*Chronic Periodontitis|*Genome-Wide Association Study|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Genetic Predisposition to Disease|Genotype|Porphyromonas gingivalis|Phenotype|Genome, Human|Cohort Studies|DAB2IP protein, human|ras GTPase-Activating Proteins|KCNK1 protein, human|Potassium Channels, Tandem Pore Domain 33 WHAMM 25015719 Eur. J. Cell Biol. 2014 10.1016/j.ejcb.2014.06.001 10 9 2 1784 *trans-Golgi Network|Arp2-3 Complex|Actin|*Protein Transport|*Cell Movement|Trans-Activators|Nuclear Proteins|Cell Nucleus|Microtubules|Golgi Apparatus|Endoplasmic Reticulum|Cytosol 33 ZBED3 25482444 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.11.106 11 0 2 98 Humans|*Mesenchymal Stem Cells|*RNA, Long Noncoding|*Chondrogenesis|*Cell Differentiation|Bone Marrow Cells|Chondrocytes|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Bioinformatic|Up-Regulation|Downregulation|ZBED3 protein, human|DNA-Binding Proteins|Transcription Factors 21 ZBED3 25263389 Mol. Carcinog. 2014 10.1002/mc.22216 3 8 0 98 Animals|Mice|Humans|delta catenin|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|NIH 3T3 Cells|Glycogen Synthase Kinase 3|HEK293 Cells|*Catenins|Lymphatic Metastasis|Cell Line, Tumor|Cell Proliferation|*Phenotype|Downregulation|Signal Transduction|Immunohistochemistry|ZBED3 protein, human|DNA-Binding Proteins|Transcription Factors 21 ZC3H12D 24913642 Electrophoresis 2014 10.1002/elps.201400175 0 0 0 498 Male|Female|hydrogen sulfite|*DNA Methylation|Mouth Mucosa|*Sulfites|Epigenetic|*Spermatozoa|Forensic Genetics|*DNA|Semen|Sequence Analysis, DNA|Body Fluids|PCR|Genetic Markers|Saliva|*Diagnostic Tests, Routine|Vagina|High-Throughput Nucleotide Sequencing 20 ZC3H12D 24721400 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2014 1 1 0 498 Rats|Animals|*Down-Regulation|*Acute Lung Injury|*Lung|Rats, Sprague-Dawley|Reperfusion Injury|*Reperfusion|Tumor Necrosis Factor-alpha|Interleukin-6|Intestines|Interleukin-1beta|*Mesenteric Ischemia|Ischemia 20 ZC3H12D 24415781 J. 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Biol. Chem. 2014 PMC4140262 10.1074/jbc.M114.567420 11 0 1 61 Humans|*Intellectual Disability|*X-Linked Gene|Palmitoylation|*Mutations|ras Proteins|protein acyltransferase|Acetyltransferases|Proteins|Palmitates|ZDHHC9 protein, human|Acyltransferases 30 zfhx4 24440720 Cell Rep 2014 PMC4041390 10.1016/j.celrep.2013.12.032 49 10 4 66 Humans|*Glioblastoma|Nucleosome Remodeling and Deacetylase Complex|Nucleosomes|*Tumor Initiating Cell|Transcription, Genetic|Autoantigens|Chromatin|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|CHD4 protein, human 26 ZNF185 25054034 Mol Clin Oncol 2014 PMC4106664 10.3892/mco.2014.298 5 0 0 64 Humans|*Colon Cancer|LIM Domain Proteins|*Liver Neoplasms|Prognosis|Cytoskeletal Proteins|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Proportional Hazards Model|Zinc Fingers 24 ZNF365 25489960 Inflamm. 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Sci. 2014 10.1167/iovs.14-14850 19 0 1 140 Humans|*Exome|*Myopia|*Mutations|*Whole Exome Sequencing|Genetic Predisposition to Disease|Pedigree|SCO2 protein, human|Carrier Proteins|Mitochondrial Proteins|SLC39A5 protein, human|Cation Transport Proteins|CTSH protein, human|Cathepsin H|LEPREL1 protein, human|ZNF644 protein, human|Transcription Factors 20 ZNF644 25142846 Zhonghua Yi Xue Za Zhi 2014 2 0 0 140 Humans|*Myopia|Chinese|Gene Frequency|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Catenins|ZNF644 protein, human|Transcription Factors|GRM6 protein, human|Receptors, Glutamate 20 ZNF644 24991186 Mol. Vis. 2014 PMC4077594 5 0 0 140 Humans|*Myopia|Genetic Predisposition to Disease|Chinese|Polymorphism, Single Nucleotide|Mutation|Case-Control Studies|Cohort Studies|ZNF644 protein, human|Transcription Factors 20 ZNF91 25274305 Nature 2014 PMC4268317 10.1038/nature13760 125 9 11 55 Humans|Mice|Animals|*Retroelements|*Short Interspersed Nucleotide Elements|*Zinc Finger|Primates|*Minisatellite Repeats|Long Interspersed Nucleotide Elements|Alu Elements|Genome, Human|Evolution, Molecular|Repressor Proteins|Binding Site|Zinc|ZFP809 protein, mouse|DNA-Binding Proteins 26 ZNF91 25070500 Genome Biol. 2014 PMC4165365 10.1186/s13059-014-0409-z 390 0 12 55 Animals|*RNA, Circular|RNA, Micro|Sequence Analysis, RNA|Gene Expression Profiling|Computational Biology|Binding Sites|*Mammals 26 ABCF2 23696857 PLoS ONE 2013 PMC3655950 10.1371/journal.pone.0063895 18 2 5 143 Animals|*Catfish|*Phylogeny|*Genome|ATP-Binding Cassette Transporters|*Membrane Transport Proteins|Multigene Family|Gene Expression Profiling|Adenosine Triphosphate 33 ABCF2 23512405 Dig. 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Biol. 2013 10.1016/j.cub.2012.11.061 27 8 6 122 Humans|Animals|Transcription Factors|Drosophila|Drosophila Proteins|Nuclear Proteins|Intracellular Signaling Peptides and Proteins|Trans-Activators|Protein-Serine-Threonine Kinases|Signal Transduction|Drosophila melanogaster|TYRP1 protein, human|*Membrane Glycoproteins|Transcriptional Activation|Promoter Regions, Genetic|Cell Proliferation|Hippo protein, human|Yorkie protein, Drosophila|Mask protein, Drosophila|DNA-Binding Proteins 24 ANKRD17 23333314 Curr. Biol. 2013 PMC4089957 10.1016/j.cub.2012.12.033 28 9 6 122 Humans|Animals|Yki protein, Drosophila|Drosophila Proteins|Nuclear Proteins|Trans-Activators|Drosophila|Transcription Factors|Intracellular Signaling Peptides and Proteins|Protein-Serine-Threonine Kinases|Drosophila melanogaster|Signal Transduction|RNAi|Hippo protein, human|Yorkie protein, Drosophila|Mask protein, Drosophila|DNA-Binding Proteins 24 AP3M2 23639161 J. Fish Biol. 2013 10.1111/jfb.12109 0 0 0 40 Animals|*Zebrafish|*Pigmentation|Chromatophore|Melanophores|Body Patterning|Neural Crest|Phenotype|Mutagenesis|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|Hermansky Pudlak Syndrome|Mutations|Gene Expression Regulation, Developmental|Retina|Larvae 25 ATL2 23914977 Clin Proteomics 2013 PMC3750387 10.1186/1559-0275-10-9 11 6 0 95 Humans|*Ciliary Body|*Proteome|Proteomics|Aqueous Humor|Anterior Chamber|Intraocular Pressure|Accommodation, Ocular|Crystalline Lens|Glaucoma|Iris 23 ATRN 24292499 Surg Radiol Anat 2013 10.1007/s00276-013-1242-x 1 0 0 64 *Peroneal Nerve|*Fibula|Cadaver 82 ATRN 24080233 J. Reprod. Immunol. 2013 PMC3965253 10.1016/j.jri.2013.08.004 6 6 0 64 Humans|Male|Mice|Animals|*Vasectomy|*T-Lymphocytes, Regulatory|Orchitis|Autoimmunity|Testis|Immune Tolerance|Epididymis|Epididymitis|Spermatogenesis|Autoimmune Diseases|Spermatozoa|Autoantibodies 82 ATRN 23998293 Andrologia 2013 10.1111/and.12151 0 0 0 64 Male|Animals|Mice|Proteomics|ATRN protein, human|*Membrane Proteins|Sertoli Cells|Testis|Two Dimensional Gel Electrophoresis|Databases, Protein|Caspase 6|Superoxide Dismutase 82 ATRN 23848512 BMC Evol. Biol. 2013 PMC3727976 10.1186/1471-2148-13-150 20 0 6 64 Humans|*Asian|Haplotypes|Gene Frequency|Selection, Genetic|Genetics, Population|European Continental Ancestry Group|Skin Pigmentation|African Continental Ancestry Group|Genetic Variation|Genotype|Polymorphism, Single Nucleotide|Linkage Disequilibrium|Evolution, Molecular|*Pigmentation Disorders|East Asia 82 ATRN 23799577 Int. J. Mol. Med. 2013 10.3892/ijmm.2013.1423 0 0 0 64 Male|Rats|Animals|Mice|*Testis|*Rats, Sprague-Dawley|Epididymis|Leydig Cells|ATRN protein, human|*Membrane Proteins|In Situ Hybridization|Spermatogonia|Spermatids|Spermatozoa|*Inferior Colliculi|Immunohistochemistry|mRNA|Blotting, Western 82 ATRN 23787699 Prion 2013 PMC3904309 10.4161/pri.25054 2 7 1 64 Animals|Mice|*Prions|Prion Disease|Mice, Knockout|Scrapie|ATRN protein, human|*Membrane Proteins|Prion Protein|Ubiquitin-Protein Ligases|Brain|Vacuoles|Disease Progression 82 ATRN 23673631 Nat Commun 2013 10.1038/ncomms2873 22 1 6 64 Mice|Animals|*Prions|*Golgi Apparatus|*Protein Transport|Prion Diseases|PrPSc Proteins|PrPC Proteins|ATRN protein, human|*Membrane Proteins|Endosomes|Cell Membrane|Lysosomes|Endocytosis|*Cell Movement|Neurons|INSR protein, human|Antigens, CD|Insulin Receptor 82 ATRN 23583561 Semin. Cell Dev. Biol. 2013 10.1016/j.semcdb.2013.03.014 32 0 5 64 Mice|Humans|Animals|*Color|*Mutations|Albinism, Oculocutaneous|Waardenburg Syndrome|Alleles|Phenotype|Melanocytes|Receptor, Endothelin B|*Mammals|Lyst protein, mouse|Proteins 82 ATRN 23331525 Pediatr Allergy Immunol 2013 10.1111/pai.12019 7 0 2 64 *Tobacco Smoke Pollution|Asthma|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Case-Control Studies 82 ATRNL1 24315873 Biochem. Biophys. Res. Commun. 2013 10.1016/j.bbrc.2013.11.121 5 9 2 17 recombinant human bone morphogenetic protein-2|BMP2 protein, human|*Bone Morphogenetic Protein 2|*Cyclic AMP Response Element-Binding Protein|Osteogenesis|Osteoblasts|Cell Differentiation|*Transforming Growth Factor beta|Core Binding Factor Alpha 1 Subunit|Cell Line|Osteocalcin|Endoplasmic Reticulum Stress|Signal Transduction|Tunicamycin 30 ATRNL1 23708773 Mol. Cells 2013 PMC3887863 10.1007/s10059-013-0083-0 0 0 0 17 Mice|Animals|*Mouse Embryonic Stem Cells|POU5F1 protein, human|Octamer Transcription Factor-3|Embryonic Stem Cells|Nanog Homeobox Protein|Pluripotent Stem Cells|Cell Differentiation|SOXB1 Transcription Factors|Homeodomain Proteins|SSEA-1|Cell Lineage|Cells, Cultured 30 BARHL1 23796904 Dev. Biol. 2013 PMC3772529 10.1016/j.ydbio.2013.06.022 27 12 0 73 Animals|Mice|Cochlear Hair Cell|Transcription Factors|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Cochlea|Ear, Inner|Stereocilia|Gene Expression Regulation, Developmental|Cell Differentiation|Nerve Tissue Proteins|*Neurogenesis|Utricle|Atoh1 protein, mouse|Pou4f3 protein, mouse|Transcription Factor Brn-3C|Barhl1 protein, mouse|Repressor Proteins 35 BARHL2 23557786 Gene Expr. Patterns 2013 10.1016/j.gep.2013.03.003 2 0 0 57 Animals|*Zebrafish|*Retina|Zebrafish Proteins|SMARCA4 protein, human|*Transcription Factor|*DNA Helicases|*Nuclear Proteins|*Cell Differentiation|Embryo, Nonmammalian|Homeodomain Proteins|Gene Expression Regulation, Developmental|Morpholinos|Gene Knockdown Techniques|In Situ Hybridization 30 BLID 23928696 Cell Death Dis 2013 PMC3763451 10.1038/cddis.2013.290 7 29 0 49 *Downregulation|*Proto-Oncogene Proteins c-akt|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|*Neoplastic Processes|Xenograft Model Antitumor Assays|Apoptosis|Cell Cycle|*Cell Transformation, Neoplastic 187 BMP2K 23692254 J. 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J. 2013 PMC3898322 10.1042/BJ20131324 14 38 3 135 Mice|Animals|*Phosphorylation|*AMP-Activated Protein Kinases|AMP-activated protein kinase kinase|*Prenylation|Enzyme Activation|S6 Kinase|AICA ribonucleotide|Ribonucleotides|cAMP Dependent Protein Kinase|Tumor Suppressor Proteins|imidazolecarboxamide|Aminoimidazole Carboxamide|Cell Line|Phenformin|Multienzyme Complexes|Post-Translational Modifications|MARK4 protein, mouse|Protein-Serine-Threonine Kinases 48 BRSK1 24128261 BioData Min 2013 PMC4015830 10.1186/1756-0381-6-17 8 10 1 135 Gene Regulatory Networks|Gene Expression Profiling|Cluster Analysis|Gene Expression Regulation, Neoplastic|Algorithms|*Cancer|Disease Progression|Signal Transduction 48 BRSK1 24103315 Maturitas 2013 10.1016/j.maturitas.2013.09.006 2 0 0 135 Humans|Female|*Primary Ovarian Insufficiency|*Ethnic Groups|*Menopause, Premature|SNPs|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Estrogen Receptor alpha|Case-Control Studies|Cohort Studies|BRSK1 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins 48 BRWD3 23973723 Gene 2013 10.1016/j.gene.2013.08.032 3 0 2 50 Male|Pregnancy|Humans|Female|*Maternal Inheritance|*Abnormalities, Multiple|Amniocentesis|Comparative Genomic Hybridization|Prenatal Diagnosis|Trisomy|Chromosome Deletion|Chromosomes, Human, X|Cytogenetic Analysis|Fetus|*Chromosome Structures|POU3F4 protein, human|POU Domain Factors|POF1B protein, human|Proteins|BRWD3 protein, human|Transcription Factors|ZDHHC15 protein, human 25 BRWD3 23479607 Proc. 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Epidemiol. 2013 PMC3955726 10.1002/gepi.21739 13 1 3 16 Humans|*Exome|Genome-Wide Association Study|Epistasis, Genetic|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Networks, Gene|*Lupus Erythematosus, Discoid|Genotype|Algorithms|Model, Linear|CMTM4 protein, human|MARVEL Domain-Containing Proteins 24 C5orf42 24178751 Hum. Genet. 2013 10.1007/s00439-013-1385-1 24 0 8 15 Child|Humans|*Syndrome|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|Ciliopathies|Cerebellar Hypoplasia|Cerebellum|Nervous System Malformations|Retina|Polydactyly|Mutations|Hypothalamic hamartomas|Hypothalamic Diseases|Phenotype|Hamartoma 24 C5orf42 24091540 Neurogenetics 2013 10.1007/s10048-013-0375-8 26 0 5 15 Child|Humans|*Whole Exome Sequencing|*Cerebellum|Cerebellar Ataxia|Atrophy|Exome|Mutations|Pedigree|Hypotonia|Intellectual Disability|*Nervous System Malformations|Developmental Disabilities|Magnetic Resonance Imaging|Epilepsy|C5orf42 protein, human 24 CARD6 24286513 Cell Prolif. 2013 PMC6496695 10.1111/cpr.12080 5 9 0 74 *Cisplatin|*Acetylcarnitine|*Cytokines|*Apoptosis|Antineoplastic Agents|Organ of Corti|Caspase 3|Hair Cells, Auditory 30 CARD6 24277158 Neurotox Res 2013 PMC3972319 10.1007/s12640-013-9443-y 10 25 1 74 Animals|Rats|*Cisplatin|*Rats, Sprague-Dawley|Proto-Oncogene Proteins c-bcl-2|*Cell Proliferation|Apoptosis|Apoptosis Regulatory Proteins|BH3 Interacting Domain Death Agonist Protein|Antineoplastic Drugs|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Membrane Proteins|mRNA|*Hippocampus 30 CARD6 23872309 Haematologica 2013 PMC3815168 10.3324/haematol.2013.092379 5 0 1 74 Humans|*Primary Myelofibrosis|Thrombocythemia, Essential|Polycythemia Vera|Myeloproliferative Disorders|*Mutations|Janus Kinase 2|Calreticulin|*Sequencing, Whole Genome|Mutation Rate|SOX30 protein, human|Tumor Suppressor Proteins|SOX Transcription Factors 30 CDC42EP4 23994638 Dev. Biol. 2013 PMC3846544 10.1016/j.ydbio.2013.08.020 1 34 0 127 Animals|*cdc42 Protein|*Neurogenesis|Body Patterning|Zebrafish Proteins|Embryo, Nonmammalian|Protein Isoforms|Zebrafish|Mesoderm|Fibroblast Growth Factor|Signal Transduction|Gene Expression Regulation, Developmental|Alternative Splicing 20 CDH16 23755150 PLoS ONE 2013 PMC3670839 10.1371/journal.pone.0064843 21 8 4 53 Mice|Animals|*Kidney|Regeneration|*Embryonic Stem Cells|Pluripotent Stem Cells|*Epithelial Cells|matrigel|Laminin|Cell Lineage|Proteoglycans|Cell Differentiation|Collagen|Kidney Tubules|TYRP1 protein, human|*Membrane Glycoproteins|Cell Line|Cells, Cultured|Induced Pluripotent Stem Cells|WNT4 protein, human 48 CDH16 23608536 Mol. Cell. Biol. 2013 PMC3700122 10.1128/MCB.01435-12 21 0 1 53 CDH1 protein, human|Cadherins|Tubule, Proximal Renal|Tight Junction|Epithelial Cell|Transcription Factors|Gene Expression Regulation|Cells, Cultured|Cell Differentiation|Cell Proliferation|Antigens, CD 48 CDH16 23420736 Genesis 2013 PMC3696052 10.1002/dvg.22381 4 1 0 53 Mice|Animals|*Mice, Transgenic|Doxycycline|Tetracycline|Integrases|Gene Expression|Transcriptional Activation|Anti-Bacterial Agents|Promoter Regions, Genetic|Trans-Activators|RNA, Messenger|Kidney|cDNA 48 CDH16 23344677 J. Mol. Med. 2013 10.1007/s00109-013-1000-x 15 0 3 53 Humans|Mice|Animals|*MicroRNAs|*Kidney|DICER1 protein, human|Dicer Enzyme|*Urinary Tract|DEAD-box RNA Helicases|Ureters|Hydronephrosis|Vesico-Ureteral Reflux|Nephrons|Ureteral Obstruction|Phenotype|Disease, Polycystic Kidney|Failure, Renal|Gene Expression Regulation, Developmental|Organogenesis|Mutation 48 CDH19 24123354 Genes Chromosomes Cancer 2013 10.1002/gcc.22110 11 1 1 36 *DNA Copy Number Variations|Neoplasm Recurrence, Local|*Neuroblastoma|N-Myc Proto-Oncogene Protein|Oncogene Proteins|*Central Nervous System Neoplasms|*Neoplasm Staging|Gene Amplification|Nuclear Proteins|Gene Expression Regulation, Neoplastic|*DNA|Cell Line, Tumor|Genes, p16|*Supratentorial Neoplasms|Disease Progression|Nervous System 25 CDH19 23285167 PLoS ONE 2013 PMC3527606 10.1371/journal.pone.0052718 11 7 2 36 *Transcriptome|Cholesteatoma, Middle Ear|Middle Ear 25 CDY1 24009201 J Zhejiang Univ Sci B 2013 PMC3773552 10.1631/jzus.B1200301 7 0 2 6 Humans|Male|*Azoospermia|China|*Infertility, Male|Deleted in Azoospermia 1 Protein|Chromosomes, Human, Y|Spermatogenesis|Oligospermia|Haplotypes|Limulus clotting factor C|*Arthropod Proteins|Gene Duplication|*Serine Endopeptidases|Gene Deletion|Asian Continental Ancestry Group|Gene Dosage|RNA-Binding Proteins|Nuclear Proteins|Polymorphism, Genetic 54 CDY1 23517283 Stem Cells Dev. 2013 10.1089/scd.2012.0660 0 0 0 6 Humans|Animals|Mice|*Neural Stem Cells|Subventricular Zone|Neurogenesis|*Brain|Neurons|Induced Pluripotent Stem Cells|Cell Differentiation|Hippocampus|Cell Proliferation|Staining|CDY1 protein, human|Nuclear Proteins 54 CECR2 24313754 J. Med. Chem. 2013 PMC3906316 10.1021/jm401568s 22 4 5 63 Nuclear Proteins|Transcription Factors|*Phthalazines|*Protein Domains|Cell Cycle Proteins|Chromatin|Structure-Activity Relationship|Crystallography, X-Ray|Models, Molecular|Cell Line, Tumor 32 CELF4 24036431 Gene 2013 10.1016/j.gene.2013.09.010 3 0 1 34 Pregnancy|Humans|Female|*Aorta, Thoracic|*Prenatal Diagnosis|Amniocentesis|Comparative Genomic Hybridization|*Prenatal Care|Chromosome Deletion|*Fetus|Haploinsufficiency|*Atrial Septal Defect|*Chromosome Structures 43 CEND1 24312406 PLoS ONE 2013 PMC3842983 10.1371/journal.pone.0082172 7 31 0 30 Mice|Animals|Ran binding protein 9|CCND1 protein, human|*Cyclin D1|*Cytoskeletal Proteins|*Nuclear Proteins|*Adaptor Proteins, Signal Transducing|Cell Differentiation|Cell Cycle|Neurons|Cell Proliferation|Nerve Tissue Proteins|Membrane Proteins|Phosphorylation|*Cell Division|Downregulation|Neuroblastoma|Cend1 protein, mouse 26 CEND1 23658157 J. Neurosci. 2013 PMC3703472 10.1523/JNEUROSCI.0119-13.2013 9 42 1 30 Animals|Mice|Nerve Tissue Proteins|Neurons|Membrane Proteins|Neurogenesis|Agenesis of Cerebellar Vermis|Cerebellum|Kidney Diseases, Cystic|Cultured Cells|Cell Differentiation|Cell Cycle|Cell Proliferation|Eye Abnormalities|Abnormalities, Multiple|Retina|Ahi1 protein, mouse|Proto-Oncogene Proteins|Cend1 protein, mouse 26 CES1P1 24362705 Nat. Chem. Biol. 2013 PMC3953460 10.1038/nchembio.1429 27 16 3 5 Mice|Animals|*Diabetes Mellitus|*Obesity|Drug Discovery|Small Molecule Libraries|Proteomics|Adipocytes 20 CES1P1 23468884 PLoS ONE 2013 PMC3585247 10.1371/journal.pone.0056861 7 1 0 5 *Gene Duplication|*Adipose Tissue|*Obesity|Adipocytes|Adiposity|Diabetes Mellitus, Type 2|Blood Glucose|Triglycerides|Insulin|mRNA|Carboxylic Ester Hydrolases 20 CFDP1 23275074 Cancer Microenviron 2013 PMC3601217 10.1007/s12307-012-0128-5 11 0 2 43 Humans|*Pericytes|Epithelial-Mesenchymal Transition|Endothelial Cells|*Pilot Projects|Melanoma|Skin Neoplasms|Cell Movement|Neovascularization, Pathologic|Brain Neoplasms|Plasminogen Activator Inhibitor 2|*Embryonic Stem Cell 40 CHD6 23954449 Mutat. Res. 2013 10.1016/j.mrfmmm.2013.07.008 35 23 4 261 *Chromatin Assembly and Disassembly|DNA Breaks, Double-Stranded|DNA Repair|Nucleosomes|Histones|DNA Helicases|Chromatin|DNA Damage|Heterochromatin|Genomic Stability|DNA 31 CHD6 23948251 Dev. Cell 2013 10.1016/j.devcel.2013.07.008 45 4 5 261 *Neurogenesis|*Gene Expression|*Polycomb-Group Proteins|Neuroblastoma|Nerve Tissue Proteins|DNA Helicases|Neurons|Gene Expression Regulation, Neoplastic|Cell Differentiation|Chromatin Assembly and Disassembly|Cell Line, Tumor 31 CHD6 23408615 J. Virol. 2013 PMC3624387 10.1128/JVI.00554-12 6 1 1 261 Humans|Mice|Animals|*Influenza, Human|*Alveolar Epithelial Cells|*Virus Replication|Influenza A viruses|Orthomyxoviridae Infections|Orthomyxoviridae|Chromatin|RNA Polymerase II|Lungs|Cell Nucleus|Cell Line|Chromatin Assembly and Disassembly|Epithelial Cells|Proteolysis|CHD6 protein, human|DNA Helicases|Nerve Tissue Proteins|Chd6 protein, mouse 31 CHD6 23318260 Cell Rep 2013 PMC3575599 10.1016/j.celrep.2012.12.009 19 42 2 261 Humans|histone H3 trimethyl Lys4|*Histones|*Protein Binding|DNA Helicases|Chromatin|Genes, Tumor Suppressor|Homeodomain Proteins|Tumor Suppressor Proteins|Nerve Tissue Proteins|Methylation|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Neuroblastoma|Cell Line, Tumor|Cell Transformation, Neoplastic|CHD5 protein, human 31 CILP2 24350279 Biomed Res Int 2013 PMC3854549 10.1155/2013/634207 3 7 1 28 Humans|Female|*Cardiovascular Diseases|Slovakia|*Risk Factors|*Polymorphism, Genetic|Angiotensin Converting Enzyme|Genotype|Gene Frequency|Lipids|APOA1 protein, human|ApoA-I|High Density Lipoprotein Cholesterol|RFLP|Blood Pressure|Apolipoproteins B|Cholesterol|Low Density Lipoprotein Cholesterol 34 CILP2 23505323 J. Med. Genet. 2013 PMC3917605 10.1136/jmedgenet-2012-101461 49 6 8 28 Humans|*Triglycerides|Studies, Genome-Wide Association|Cholesterol, HDL|Apolipoprotein A-V|Apolipoproteins A|Cholesterol, LDL|*Lipids|Genotype|European Continental Ancestry Group|Apolipoproteins B|Polymorphism, Single Nucleotide|Dyslipidemias|Genetic Predisposition to Disease|*Genomics|Mexico 34 CILP2 23457408 J. Clin. Endocrinol. Metab. 2013 10.1210/jc.2012-4169 26 1 4 28 *Insulin|*Insulin Resistance|*Alleles|*Diabetes Mellitus, Type 2|Denmark|*Insulin, Regular, Human|Single Nucleotide Polymorphisms|BCAR1 protein, human|*Crk-Associated Substrate Protein|*Cohort Studies|GRB14 protein, human|*Adaptor Proteins, Signal Transducing|Glucose Tolerance Test|Genotype|Genetic Predisposition to Disease|Genome-Wide Association Study|Case-Control Studies|*Risk 34 CLIC6 23535966 J. Hum. Genet. 2013 10.1038/jhg.2013.20 3 0 0 37 Humans|*Whole Exome Sequencing|*Exome|*Genetic Linkage|Pedigree|Haplotype|Allele Frequency|*Goiter|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Sequence Analysis, DNA|Asian Continental Ancestry Group|Heterozygote|Mutation, Missense|Mutation 21 CLMN 24085853 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3800992 10.1073/pnas.1309219110 23 5 1 48 Mice|Animals|*Actins|*Proteomics|AVP protein, human|*Vasopressin|*Neurophysins|Aquaporin 2|Kidney Collecting Duct|Antidiuretic Agents|*Plasma Membrane|Protein Transport|Deamino Arginine Vasopressin|Forskolin|Mass Spectrometry|Cyclic AMP|Phosphorylation|Mpp5 protein, mouse|Membrane Proteins|Nucleoside-Phosphate Kinase 29 CLMN 23817466 Oncogenesis 2013 PMC3740285 10.1038/oncsis.2013.15 24 6 7 48 Humans|*Tumor Suppressor Protein p53|Activation, Transcriptional|Promoter Regions, Genetic|Mutation|Transcription Factor|Gene Expression Regulation|Downregulation|Upregulation|Transcriptome|ARID3B protein, human|DNA-Binding Proteins|PRPF40A protein, human|Carrier Proteins 29 CLMN 23579966 Am J Cardiovasc Drugs 2013 10.1007/s40256-013-0024-5 7 0 0 48 Humans|*Pharmacogenetics|*Cardiovascular Diseases|Prospective Studies|CYP2C9 protein, human|Cytochrome P-450 CYP2C9|Vitamin K Epoxide Reductase|Warfarin|CYP2C19 protein, human|CYP2C19|Anticoagulant|CYP2D6|Statins|Clopidogrel|Cardiovascular Agents|HMGCR protein, human|Hydroxymethylglutaryl CoA Reductases|Single Nucleotide Polymorphisms|VKORC1 protein, human 29 CLSTN2 23658629 PLoS ONE 2013 PMC3637299 10.1371/journal.pone.0062431 6 15 0 215 *Amyloid Precursor Protein Secretases|Amyloid beta-Protein Precursor|Presenilin-1|Amyloid beta-Peptides|Alzheimer Disease|Peptide Fragments|peptide P3|Carrier Proteins 32 cornulin 23977449 Am J Cancer Res 2013 PMC3744019 4 0 0 53 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Transcriptome|Carcinoma, Squamous Cell|Microdissection|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Esophagus|Gene Expression Regulation, Neoplastic|In Situ Hybridization|Epithelium 27 cornulin 23894350 PLoS ONE 2013 PMC3722219 10.1371/journal.pone.0068838 8 4 2 53 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Downregulation|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Cell Cycle Arrest|Cyclin-Dependent Kinase Inhibitor p21|Cell Line, Tumor|mRNA|Tumor Suppressor Protein p53|Cell Proliferation|Upregulation|Apoptosis|RNA Interference 27 cornulin 23497009 BMC Genomics 2013 PMC3610128 10.1186/1471-2164-14-169 8 11 0 53 Animals|*Columbidae|*Milk|*Transcriptome Analysis|Epidermis|Keratinocytes|*Cell Differentiation|*Organogenesis|Epidermal Cells|Keratins|*Apoptosis|Triglycerides 27 COX6A2 23861375 Endocrinology 2013 PMC3776861 10.1210/en.2012-1877 14 3 1 26 Pregnancy|Male|Female|Humans|Animals|Mice|Infant|*Diet, High-Fat|*Lactation|Maternal Nutritional Physiological Phenomena|Insulin Resistance|Weaning|Obesity|Body Weight|Adiposity|Prenatal Exposure Delayed Effects|Insulin|Liver|Pregnancy Complications|Adipocytes|ATP5I protein, human 24 COX6A2 23460811 PLoS ONE 2013 PMC3584060 10.1371/journal.pone.0056719 27 12 2 26 Mice|Animals|*Insulin Resistance|*Diet, High-Fat|*Electron Transport|*Obesity|Energy Expenditure|Body Weight|Muscle, Skeletal|Uncoupling Protein 1|Mitochondrial Proteins|AMP-Activated Protein Kinase|Ion Channels|Glucose Intolerance|Mitochondria|Insulin|Blood Glucose|Electron Transport Complex IV|Glucose 24 CPA6 24290490 Epilepsy Res. 2013 10.1016/j.eplepsyres.2013.10.007 6 5 1 44 Adult|Humans|Child|*Seizures, Febrile|*Epilepsy, Focal|Epilepsy, Temporal Lobe|Genetic Linkage|Epilepsy|*Promoter Regions, Genetic|Pedigree|Seizures|Genotype|Polymorphism, Single Nucleotide|Drugs, Antiepileptic|DNA Methylation|Fever 24 CPA6 23800278 J. Gastroenterol. Hepatol. 2013 10.1111/jgh.12310 0 0 3 44 Humans|Child|*Sorafenib|*Liver Neoplasms|*Carcinoma, Hepatocellular|*Ascites|Phenylurea Compounds|Niacinamide|Antineoplastic Agents|Prognosis|Protein Kinase Inhibitors|Treatment Outcome|Retrospective Studies|Disease Progression 24 CROCC 24035387 Cell Rep 2013 10.1016/j.celrep.2013.08.005 32 13 3 82 Humans|*Centrosome|Centrioles|Interphase|Cell Cycle Proteins|Spindle Apparatus|Mitosis|NIMA-Related Kinases|Protein-Serine-Threonine Kinases|Cytoskeletal Proteins|Cell Cycle|Phosphorylation|HeLa Cells|Autoantigens 32 CRTAC1 23277195 Biochim. Biophys. Acta 2013 10.1016/j.bbapap.2012.12.012 1 0 0 35 Animals|Humans|*Calcium-Binding Proteins|Binding Sites|Amino Acid Sequence|Calcium|Circular Dichroism|Seabream|*Cartilage|Protein Isoforms|Spectrometry, Fluorescence|Chondrocyte|CRTAC1 protein, human 27 CRYBB3 24319337 Mol. Vis. 2013 PMC3850972 7 2 0 14 Humans|*Cataract|gamma-Crystallins|DNA Mutational Analysis|Pedigree|Mutations|Connexins|Sequence Alignment|Base Sequence|Eye Proteins|Amino Acid Sequence|Asian Continental Ancestry Group 36 CRYBB3 24265016 Invest. Ophthalmol. Vis. Sci. 2013 10.1167/iovs.13-12221 21 1 3 14 Mice|Animals|*Mesenchymal Stem Cells|neurotrophin 4|*Neuroprotective Agents|*Nerve Growth Factors|Retinal Degeneration|Mesenchymal Stem Cell Transplantation|*Disease Models, Animal|Retina|Electroretinography|Gene Therapy|*Neuroprotection 36 CRYBB3 23978599 Exp. Eye Res. 2013 PMC3888992 10.1016/j.exer.2013.08.001 11 6 3 14 Humans|Animals|Mice|Rats|*Crystallin|*Gene Regulatory Networks|*Mice, Inbred DBA|Transcription Factor|Lens, Crystalline|Retina|Homeodomain Proteins|mRNA|Gene Expression Regulation|Mice, Inbred C57BL|Transcriptional Activation|CRYBA1 protein, human|beta-Crystallin A Chain|CRYBB3 protein, human|beta-Crystallin B Chain|CRYGD protein, human|gamma-Crystallins|Cryba1 protein, mouse 36 CRYBB3 23508780 Hum. Genet. 2013 PMC3683360 10.1007/s00439-013-1289-0 29 1 7 14 Child|Humans|*Alleles|*Whole Exome Sequencing|gamma-Crystallins|Cataract, Autosomal Dominant|*Cataract|Pedigree|DNA Mutational Analysis|Genes, Dominant|Phenotype|Mutation|Mutation, Missense|Amino Acid Sequence|CRYBB1 protein, human|beta-Crystallin B Chain|CRYBB3 protein, human|CRYGD protein, human 36 CRYGC 24315440 Cell Stem Cell 2013 10.1016/j.stem.2013.10.016 175 0 21 132 Mice|Animals|*CRISPR-Cas Systems|*CRISPR|CRISPR-Associated Proteins|Guide RNA|Mutation|Alleles|Zygotes|Oligonucleotides 65 CRYGC 24281366 Eur. J. Hum. Genet. 2013 PMC4060118 10.1038/ejhg.2013.268 22 0 3 132 Humans|*Whole Exome Sequencing|*Exome|CYP1B1 protein, human|*Cytochrome P-450 CYP1B1|Peters anomaly|Eye Abnormalities|Paired Box Transcription Factors|Microphthalmia and mental deficiency|Corneal Opacity|Microphthalmos|Aniridia|Coloboma|Eye Proteins|PAX6 Transcription Factor|Anterior Eye Segment|Homeodomain Proteins|DNA Mutational Analysis|Repressor Proteins 65 CUZD1 24097894 Clin. Chem. 2013 10.1373/clinchem.2013.215236 11 0 3 24 *Antigen CA 125|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|*ELISA|Biomarkers, Tumor|Membrane Proteins|Proteomics 35 CYP4X1 24255117 Drug Metab. Dispos. 2013 PMC3912540 10.1124/dmd.113.054239 0 1 0 8 Male|Female|Animals|Rats|Mice|*Cytochrome b|*Rodent|cytochrome P-450 4X1|*Cytochrome P-450 Enzyme System|CYP2B6 protein, human|*Cytochrome P-450 CYP2B6|CYP1A2 protein, human|CYP1A2|Enzyme Induction|Liver|Phenobarbital|Gene Expression Regulation, Enzymologic|*Brain|RNA, Messenger 26 CYP4X1 23274569 Toxicol. Appl. Pharmacol. 2013 10.1016/j.taap.2012.12.008 2 0 1 8 Male|Female|Humans|Child|*Proteomics|arachidonate epoxygenase|*Cytochrome P-450 Enzyme System|cytochrome P-450 4X1|*Mass Spectrometry|Microsomes, Liver|*Liver|CYP2E1|Isozymes|Amino Acid Sequence|Cytochrome P-450 CYP1A1|Peptides|CYP4F11 protein, human|Cytochrome P450 Family 4|CYP4V2 protein, human|CYP2W1 protein, human|Cytochrome P450 Family 2 26 DACH2 23727239 Cell Rep 2013 PMC5293199 10.1016/j.celrep.2013.04.035 29 10 1 37 Humans|*Glioma|*Cells, Glial|Brain Neoplasms|Neoplastic Stem Cells|Cell Movement|AC133 Antigen|Cell Differentiation|Gene Expression Regulation, Neoplastic|Antigens, CD|Cell Line, Tumor 36 DACH2 23419240 Gene Expr. Patterns 2013 10.1016/j.gep.2013.02.001 5 0 0 37 Female|Pregnancy|Cattle|Animals|Mice|Muscle Development|Myogenic Regulatory Factor 5|MyoD Protein|PAX7 Transcription Factor|Myogenin|Cell Differentiation|Muscle Fibers, Skeletal|Gene Expression Regulation, Developmental|Muscle, Skeletal|Muscular Diseases|Hes6 protein, mouse|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Eya2 protein, mouse|Nuclear Proteins|Protein Tyrosine Phosphatases|Intracellular Signaling Peptides and Proteins 36 DAZ3 23512232 World J Urol 2013 10.1007/s00345-013-1058-7 3 0 3 1 20 DDX10 24291026 Gene 2013 10.1016/j.gene.2013.11.029 17 0 3 68 Child|Humans|*Intellectual Disability|Comparative Genomic Hybridization|DNA Copy Number Variations|Russia|Developmental Disabilities|Chromosome Aberrations|*Cohort Studies 29 DDX10 23522748 Cancer Genet 2013 10.1016/j.cancergen.2013.02.001 2 0 0 68 nuclear pore complex protein 98|In Situ Hybridization, Fluorescence|*Leukemia, Myeloid, Acute|Nuclear Pore Complex Proteins|DDX10 protein, human|*DEAD-box RNA Helicases|Translocation, Genetic|Leukemia, Myelomonocytic, Acute|Chromosome Inversion|Oncogene Proteins, Fusion|Amino Acid Sequence|*Isoforms|Base Sequence 29 DDX10 23496902 BMC Genomics 2013 PMC3600027 10.1186/1471-2164-14-165 7 3 0 68 Humans|*Rearrangements, Gene|Oligonucleotide Array Sequence Analysis|Cell Line, Tumor|Chromosome Aberrations|Massively Parallel Sequencing|Cell Transformation, Neoplastic|Genome, Human|RNA, Messenger 29 DDX25 24291337 Mech. Dev. 2013 10.1016/j.mod.2013.11.002 5 0 2 41 Animals|*Xenopus laevis|*mRNA|*Germ Cells|3' Untranslated Region|RNA, Micro|DEAD-box RNA Helicases|Gene Expression Regulation, Developmental|Zygotes|Sequence Alignment|Cell Movement|Amino Acid Sequence 39 DDX25 24168058 Andrologia 2013 10.1111/and.12185 0 0 0 41 Male|Humans|*Infertility, Male|*Testis|Spermatogenesis|*Gonadotropin|DEAD-box RNA Helicases|Genotypes|Allele|Polymorphism, Single Nucleotide 39 DDX25 23587717 Biochim. Biophys. Acta 2013 10.1016/j.bbagrm.2013.04.005 30 0 2 41 Male|Humans|Animals|Mice|*RNA|vas protein, Drosophila|Drosophila Proteins|DEAD-box RNA Helicases|Drosophila|Drosophila melanogaster|Germ Cell|*DNA Helicases|Gametogenesis|Caenorhabditis elegans|Developmental Biology|Ddx25 protein, mouse 39 DDX25 23579190 Reproduction 2013 10.1530/REP-12-0362 15 0 4 41 Mice|Male|Animals|*Haploidy|Spermatids|Spermatogenesis|DICER1 protein, human|Ribonuclease III|RNA-Binding Proteins|mRNA|Spermatocytes|DEAD-box RNA Helicases|Gene Expression Regulation|Protein Biosynthesis|MicroRNAs|Open Reading Frames|*Mammals|Ddx25 protein, mouse|Cpeb1 protein, mouse|Transcription Factors|mRNA Cleavage and Polyadenylation Factors 39 DDX25 23546600 Endocrinology 2013 PMC3740490 10.1210/en.2012-2230 5 2 0 41 Mice|Male|Animals|*Testis|*Gonadotropin|Spermatogenesis|*Androgens|Spermatid|Leydig Cells|*Gene Expression Regulation|DEAD-box RNA Helicases|Flutamide|Androgen Receptor Antagonists|Mice, Transgenic|RNA, Messenger|Regulatory Regions|Sequence, 5' Flanking|Promoter Regions, Genetic|Ddx25 protein, mouse 39 DDX25 23429978 Biol Open 2013 PMC3575653 10.1242/bio.20123111 2 3 0 41 Animals|Mice|*Xenopus laevis|*Germ Cells|*Cytoplasm|Xenopus Proteins|red fluorescent protein|Luminescent Proteins|3' Untranslated Region|Oocytes|mRNA|TYRP1 protein, human|*Membrane Glycoproteins|Animals, Genetically Modified|RNA Helicases|Amino Acid Sequence|Gene Expression Regulation, Developmental|Green Fluorescent Proteins|Ddx25 protein, mouse|DEAD-box RNA Helicases 39 DDX25 23412502 Histochem. Cell Biol. 2013 10.1007/s00418-012-1067-4 7 1 3 41 Male|Rats|Animals|Spermatids|Spermatocytes|Spermatogenesis|Spermatogonia|Sperm|Microscopy, Immunoelectron|Immunofluorescence|DEAD-box RNA Helicases|Mitochondria|Ddx4 protein, rat 39 DEXI 24146783 PLoS ONE 2013 PMC3797717 10.1371/journal.pone.0075829 2 1 0 27 *Triticum|Plant Diseases|Crops, Agricultural|Agriculture|Software 30 DGCR6 24345872 Braz. J. Med. Biol. Res. 2013 PMC3932972 10.1590/1414-431X20132809 4 8 1 67 Humans|Adult|*Histones|*Glomerulonephritis, Membranous|*Leukocytes, Mononuclear|*Chromatin Immunoprecipitation Sequencing|CpG Islands|Chromatin Immunoprecipitation|Epigenetic|Lysine|DNA Methylation|*Protein Processing, Post-Translational|Oligonucleotide Array Sequence Analysis|*Leukocytes|Nephrosis, Lipoid|*Mononuclear Phagocyte System 24 DGCR6 23442539 Int. J. Neuropsychopharmacol. 2013 10.1017/S1461145713000035 20 0 4 67 Humans|Leukocytes, Mononuclear|*Antipsychotic Agents|*Schizophrenia|Risperidone|Haloperidol|*Gene Expression Profiling|Gene Expression Regulation|*Microarray Analysis|Up-Regulation|Gene Expression Profiles|Downregulation|Genome|AKT1 protein, human|Proto-Oncogene Proteins c-akt 24 DKKL1 24190897 J. Endocrinol. 2013 PMC3947288 10.1530/JOE-13-0212 2 23 0 98 Humans|Mice|Animals|VDR protein, human|*Receptors, Calcitriol|*Keratinocytes|Activation, Transcriptional|Transcription Factors|Thyroid Hormone Receptor|dihydroxy-vitamin D3|Vitamin D|Signal Transduction|*Gene Expression|Protein Binding|Ligands|Cell Line|SOSTDC1 protein, human|Proteins|DKKL1 protein, human|Intercellular Signaling Peptides and Proteins 22 DKKL1 23295900 Neurosci. Lett. 2013 10.1016/j.neulet.2012.12.040 2 0 0 98 Male|Animals|Mice|*Brain|Nuclear Proteins|Neurons|Spermatocyte|DNA-Binding Proteins|Testis|RNA, Messenger|Apoptosis|Mice, Transgenic|Hippocampus 22 DLEU7 24014303 Adv. Exp. Med. Biol. 2013 PMC4088930 10.1007/978-1-4614-8051-8_14 8 30 1 16 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|MicroRNAs|Gene Expression Regulation, Leukemic|Proto-Oncogene Proteins|13q deletion syndrome|Chromosome Deletion|Disease Progression|Chromosomes, Human, Pair 13 23 DLEU7 23861223 Am. J. Hematol. 2013 10.1002/ajh.23545 9 1 1 16 Humans|Adult|*Waldenstrom Macroglobulinemia|Loss of Heterozygosity|DNA Copy Number Variations|Comparative Genomic Hybridization|Genomics|Chromosome Aberrations|Gene Expression Profiling|*Lymphoma, B-Cell|Uniparental Disomy|Polymorphism, Single Nucleotide 23 DLEU7 23547850 Int J Clin Pharmacol Ther 2013 10.5414/CP201851 8 0 2 16 Humans|*Oxaliplatin|Japan|*Colorectal Cancer|*Colonic Neoplasms|Organoplatinum Compounds|*Neurotoxicity Syndromes|Leucovorin|Fluorouracil|Single Nucleotide Polymorphisms|Antineoplastic Combined Chemotherapy Protocols|Endonucleases|Genome-Wide Association Study|Deoxycytidine|DNA-Binding Proteins|Pharmacogenetics|Genotype|CAMK2N1 protein, human|Proteins 23 dnajc10 23769672 Mol. Cell 2013 PMC3906653 10.1016/j.molcel.2013.05.014 35 13 3 331 Animals|*Disulfides|*Reductase|*Endoplasmic Reticulum|HSP40 Heat-Shock Proteins|Molecular Chaperones|Protein Folding|LDLR protein, human|*LDL Receptor|Protein Disulfide-Isomerases|Heat-Shock Proteins|Membrane Proteins|Cytosol|*Cell Communication|Cell Line 32 dnajc10 23641861 Antioxid. Redox Signal. 2013 PMC3887457 10.1089/ars.2012.5051 23 0 3 331 Animals|Humans|*Caenorhabditis elegans|*Neurodegenerative Diseases|Caenorhabditis elegans Proteins|Amyloid beta-Peptides|HSP40 Heat-Shock Proteins|Proteostasis|RNA Interference|Proteasome Endopeptidase Complex|Endoplasmic Reticulum|Disease Models, Animal 32 dnajc10 23363602 Mol. Biol. Cell 2013 PMC3596249 10.1091/mbc.E12-07-0522 23 35 2 331 *Cholera Toxin|Molecular Chaperones|Endoplasmic Reticulum|HSP40 Heat-Shock Proteins|Heat-Shock Proteins|Protein Folding|HSP70 Heat-Shock Proteins|Protein Disulfide-Isomerases|E3 Ubiquitin Ligase|Membrane Proteins|Protein Binding|Cytosol|RNA, Small Interfering 32 DOC2A 24356452 Mol. Biol. Cell 2013 PMC3923640 10.1091/mbc.E13-10-0571 11 8 0 31 SYT1 protein, human|Synaptotagmin I|*Synaptic Transmission|Synaptic Vesicles|C2 Domains|Calcium-Binding Proteins|Neurons|Plasma Membrane|Nerve Tissue Proteins|*Mutations|Calcium|Protein Binding|Ligands 42 DRP2 23999528 Mol. Psychiatry 2013 10.1038/mp.2013.106 34 0 5 48 Humans|*Whole Exome Sequencing|*Autistic Disorder|*Exome|*Heterozygote|Mutation|Genetic Predisposition to Disease|Siblings|Sequence Analysis, DNA 49 DRP2 23308041 Future Neurol 2013 PMC3539824 10.2217/FNL.12.68 43 51 4 48 Nerve Tissue Proteins|Intercellular Signaling Peptides and Proteins|Axons|*Motor Neuron|Phosphorylation|Post-Translational Modifications|Signal Transduction 49 EHBP1 24324931 Front Oncol 2013 PMC3839295 10.3389/fonc.2013.00288 3 4 0 98 Humans|*Neoadjuvant Therapy|*Rectal Cancer|Chemoradiotherapy, Adjuvant|Fluorouracil|Adenocarcinoma|Treatment Outcome|*Antimetabolites 29 EHBP1 24040268 PLoS ONE 2013 PMC3769341 10.1371/journal.pone.0074519 11 37 0 98 Humans|Chlorocebus aethiops|Animals|*Phosphatidylinositol|HeLa Cells|*Plasma Membrane|Binding Proteins|ADP-ribosylation factor 6|ADP-Ribosylation Factors|Protein Transport|EPS15 protein, human|Adaptor Proteins, Signal Transducing|Endosomes|Actin|COS Cells|Vesicular Transport Proteins|Intracellular Membranes|Amino Acid Sequence|Vacuoles|EHD3 protein, human|EHD2 protein, human 29 EHBP1 23923645 Pharmazie 2013 4 1 0 98 ATP Binding Cassette Transporter, Subfamily G, Member 2|*Farnesol|Neoplasm Proteins|Drug Resistance, Multiple|P Glycoprotein|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B|ATP-Binding Cassette Transporters|Drug Resistance, Neoplasm|*Sesquiterpenes|Cell Line, Tumor|Antineoplastic Agents|Doxorubicin|Pharmacogenetics|Cell Survival|Apoptosis 29 EHBP1 23788431 J. Cell. Sci. 2013 PMC3744027 10.1242/jcs.126292 3 0 1 98 Animals|*Drosophila|Drosophila Proteins|Receptors, Notch|Photoreceptor Cells, Invertebrate|*Cell Differentiation|Drosophila melanogaster|Intracellular Signaling Peptides and Proteins|Signal Transduction|Membrane Proteins|Gene Expression Regulation, Developmental|Repressor Proteins|Exocytosis|*Cell Communication|notch protein, Drosophila|scabrous protein, Drosophila 29 EHBP1 23593118 PLoS ONE 2013 PMC3617165 10.1371/journal.pone.0058195 8 2 0 98 Humans|Male|*Genetic Predisposition to Disease|*Genetic Loci|Single Nucleotide Polymorphisms|Odds Ratios|Genotypes|Alleles|Logistic Regression|*Pesticides|Case-Control Studies|Prostate Cancer|Risk Factors|Risk Assessment 29 EIF1AY 23829492 Biomarkers 2013 10.3109/1354750X.2013.811538 11 0 1 31 Humans|Oligonucleotide Array Sequence Analysis|*Biomarkers|Gene Expression Profiling|RNA, Long Noncoding|DEAD-box RNA Helicases|RNA, Messenger|Minor Histocompatibility Antigens 26 EPB41L4B 23664528 J. Dermatol. Sci. 2013 10.1016/j.jdermsci.2013.04.008 4 3 2 90 *Keratinocytes|*Cell Movement|*Wound Healing|Cytoskeletal Proteins|*Tissue Adhesions|Cell Line, Tumor 23 EPB41L4B 23662806 Biochem. J. 2013 10.1042/BJ20121642 22 0 3 90 Humans|radixin|Cytoskeletal Proteins|ezrin|Membrane Proteins|moesin|Microfilament Proteins|Phosphoproteins|Protein Structure, Tertiary|Amino Acid Sequence|Protein Binding 23 ESX1 24371809 Stem Cell Reports 2013 PMC3871400 10.1016/j.stemcr.2013.10.006 30 24 3 100 *Cell Differentiation|Embryonic Stem Cells|Cell Lineage|Neurons|Hepatocytes|GATA3 protein, human|GATA3 Transcription Factor|Basic Helix-Loop-Helix Transcription Factors|GATA2 protein, human|GATA2 Transcription Factor|SOX9 protein, human|SOX9 Transcription Factor|Gene Expression Profiling|SMAD7 protein, human|Smad7 Protein|Hepatocyte Nuclear Factor 3-alpha 73 ETV3 23824578 Development 2013 10.1242/dev.093716 9 7 1 1655 Animals|*Retinoic Acid|*Neurogenesis|*Transcription Factors|ERF protein, human|*Repressor Proteins|Xenopus laevis|Cell Differentiation|Xenopus Proteins|Signal Transduction|Gene Expression Regulation, Developmental|Neurons|Nervous System 23 ETV3 23329352 Breast Cancer Res. Treat. 2013 10.1007/s10549-013-2408-2 12 0 2 1655 Humans|*ets Transcription Factors|*DNA Copy Number Variations|Carcinoma, Ductal, Breast|Transcription Factors|DNA-Binding Proteins|Gene Amplification|Prognosis|Chromosome Aberrations|*Chromosome Structures|Gene Expression|Genes, myc|*Breast Neoplasms|ETV3 protein, human|ELF3 protein, human 23 FAIM3 24250831 PLoS ONE 2013 PMC3826713 10.1371/journal.pone.0081299 5 12 0 72 Mice|Sheep|Animals|*T Cells|Germinal Center|B-Lymphocytes|immunoglobulin M receptor|Receptors, Fc|Immunoglobulin M|Responses, Antibody|Dendritic Cells, Follicular|Transformation, Blast|*Complement Factor B|Complement Activation|Humoral Immune Response|Antigen|Flow Cytometry|Immunization 23 FAIM3 23359703 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3574925 10.1073/pnas.1222264110 22 0 1 72 Mice|Animals|*Monocytes|*Neutrophils|*Granulocytes|*Macrophages|*Leukocyte Count|Listeriosis|Listeria monocytogenes|Innate Immune Responses|Lipopolysaccharides|Carrier Proteins|Membrane Proteins|Fc Receptors|Septic Shock|TOSO protein, mouse 23 FAM167A 24162006 Arch. Dis. Child. 2013 PMC3888612 10.1136/archdischild-2012-302841 42 3 4 62 Humans|Child|*Mucocutaneous Lymph Node Syndrome|Tumor Necrosis Factor-alpha|Coronary Aneurysm|Immunoglobulins, Intravenous|Aspirin|Corticosteroids|Inflammation|Arteries, Coronary|CASP3 protein, human|CASP3|Japan|FCGR3B protein, human|Receptors, IgG|GPI-Linked Proteins|FAM167A-BLK protein, human 25 FAM167A 24097067 Nat. Genet. 2013 PMC3867192 10.1038/ng.2792 117 8 11 62 Humans|Sjogren's Syndrome|Histocompatibility Antigens Class II|STAT4 Transcription Factor|IRF5 protein, human|Interferon Regulatory Factors|Autoimmune Disease|Genetic Predisposition to Disease|Xerostomia|TNFAIP3 protein, human|Tumor Necrosis Factor alpha-Induced Protein 3|Histocompatibility Antigens|TNIP1 protein, human|DNA-Binding Proteins|FAM167A-BLK protein, human|ITSN2 protein, human|Adaptor Proteins, Vesicular Transport|TNPO3 protein, human|beta Karyopherins 25 FAM167A 23899688 Clin. Exp. Rheumatol. 2013 5 2 0 62 Humans|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Haplotypes|Alleles|Epistasis, Genetic|Genotype|Case-Control Studies|Adaptor Proteins, Signal Transducing|Membrane Proteins|*Genes, src|*Syndrome|Autoimmune Diseases|FAM167A-BLK protein, human|BLK protein, human|src-Family Kinases 25 FAM167A 23635951 J. Hum. Genet. 2013 10.1038/jhg.2013.26 11 1 3 62 Humans|*Sjogren's Syndrome|TNFSF4 protein, human|*OX40 Ligand|*Asian Continental Ancestry Group|TNFAIP3 protein, human|*Tumor Necrosis Factor alpha-Induced Protein 3|Single Nucleotide Polymorphisms|Haplotypes|Genetic Predisposition to Disease|Gene Frequency|Alleles|Genotype|Case-Control Studies|Cohort Studies|FAM167A-BLK protein, human|BLK protein, human|src-Family Kinases 25 farp1 23375260 Structure 2013 PMC3595398 10.1016/j.str.2013.01.001 18 17 2 105 *Guanine Nucleotide Exchange Factor|RASGRF1 protein, human|*ras-GRF1|Protein Structure, Tertiary|Amino Acid Sequence|Crystallography, X-Ray|Binding Site|Pleckstrin Homology Domains|Sequence Homology, Amino Acid|Models, Molecular|Catalysis 26 FASTK 24013584 PLoS ONE 2013 PMC3754986 10.1371/journal.pone.0072390 17 29 2 83 Humans|Adult|*Astrocytoma|*Apoptosis|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Genes, Tumor Suppressor|3' Untranslated Regions|Downregulation|Cell Line, Tumor|Brain Neoplasms|Upregulation|*Phosphorylation|Kaplan-Meier Analysis 24 FCRL1 23950870 PLoS ONE 2013 PMC3737236 10.1371/journal.pone.0068439 6 4 2 2 Humans|*Liver Cancer|Carcinoma, Hepatocellular|*DNA Methylation|Promoter Regions, Genetic|Biomarkers, Tumor|Hepatitis B, Chronic|MAGEA12 protein, human|Neoplasm Proteins|FCRL1 protein, human|Membrane Proteins|Liver|Gene Expression Regulation, Neoplastic|Antigens, Neoplasm|Prognosis|*Genetic Markers|PCR|DNA|Bangladesh 34 FCRL1 23505439 PLoS ONE 2013 PMC3591391 10.1371/journal.pone.0057758 9 5 2 2 Humans|*Genome-Wide Association Study|*Graves Disease|SNPs|Alleles|Genetic Predisposition to Disease|Haplotypes|Asian Continental Ancestry Group|Gene Frequency|Linkage Disequilibrium|Genotype|Case-Control Studies|FCRL1 protein, human|Membrane Proteins 34 Fcrla 24339877 PLoS ONE 2013 PMC3855087 10.1371/journal.pone.0080666 12 4 3 38 Rats|Animals|*Habenula|*Depression|Antidepressive Agents|Anhedonia|Rats, Wistar|Stress, Psychological|Disease Models, Animal 27 Fcrla 23742757 Immunol. Lett. 2013 10.1016/j.imlet.2013.05.011 2 4 1 38 Humans|*Isoforms|Peptide, Signal|Amino Acid Sequence|B-Lymphocytes|Alternative Splicing|Exons|Endoplasmic Reticulum|Transfection|Glycosylation|Biological Transport|FCRLA protein, human|Receptors, Immunologic 27 fes1 23899645 Plant Physiol. 2013 PMC3762645 10.1104/pp.113.223958 7 0 1 198 *Arabidopsis|*Protein C|Arabidopsis Proteins|MADS Domain Proteins|Gene Expression Regulation, Plant|Flowers|Chromatin|Histones|Transcriptional Activation|*Seasons|Mutations|Phenotype|SUF4 protein, Arabidopsis|Trans-Activators 35 fes1 23797105 G3 (Bethesda) 2013 PMC3737180 10.1534/g3.113.007112 8 6 3 198 *Saccharomyces cerevisiae|*Prions|*Molecular Chaperones|Saccharomyces cerevisiae Proteins|HSP110 Heat-Shock Proteins|HSP70 Heat-Shock Proteins|*Yeast, Dried|structure-specific endonuclease I|*Endonucleases|*DNA Mutational Analysis|Adenosine Triphosphatases|Cytosol|Nucleotides|SSE1 protein, S cerevisiae 35 fes1 23530227 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3625341 10.1073/pnas.1216778110 28 0 5 198 *Ubiquitin|Neurodegenerative Diseases|*HSP70 Heat-Shock Proteins|*Cytosol|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Molecular Chaperones|Proteasome Endopeptidase Complex|HSP40 Heat-Shock Proteins|Protein Folding|Proteolysis|Adenosine Triphosphatases|Ubiquitylation|Ubiquitin-Protein Ligases|Protein Binding|3'-(1-butylphosphoryl)adenosine|*Nucleotides|Heat-Shock Response 35 FILIP1 24327474 Int. J. Cancer 2013 PMC3991758 10.1002/ijc.28662 16 41 2 40 Humans|Female|*Wnt Signaling Pathway|*Filamins|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|beta Catenin|Ovarian Cancer|Cell Migration|*MMPs|Cell Line, Tumor|Downregulation|Lung Neoplasms|Matrix Metalloproteinase 9 22 FILIP1 23414321 Epigenomics 2013 PMC3731941 10.2217/epi.12.67 0 13 0 40 Humans|Male|*Promoter Regions, Genetic|*Prostate Cancer|DNA Methylation|CpG Islands|Decitabine|Azacitidine|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 22 FILIP1 23277876 Allergy Asthma Immunol Res 2013 PMC3529227 10.4168/aair.2013.5.1.34 1 1 0 40 Humans|*Aspirin|Republic of Korea|Asthma, Aspirin-Induced|*Asthma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Forced Expiratory Volume|Haplotypes|Asian Continental Ancestry Group|Genotype 22 FJX1 24291026 Gene 2013 10.1016/j.gene.2013.11.029 0 0 3 72 Child|Humans|*Intellectual Disability|Comparative Genomic Hybridization|DNA Copy Number Variations|Russia|Developmental Disabilities|Chromosome Aberrations|*Cohort Studies 26 FJX1 23922772 PLoS ONE 2013 PMC3726759 10.1371/journal.pone.0069660 7 16 2 72 Humans|Mice|Animals|*Colorectal Carcinoma|*Neovascularization, Pathologic|Cell Proliferation|HCT116 Cells|Adenoma|Azoxymethane|Gene Expression Regulation, Neoplastic|Mice, Athymic|Adenocarcinoma|Cell Line, Tumor|Carcinomas|Colon|Upregulation|FJX1 protein, human|Membrane Proteins 26 FKBP11 24058703 PLoS ONE 2013 PMC3776769 10.1371/journal.pone.0075831 10 11 1 61 Animals|*Lipoylation|Influenza A Virus, H1N1 Subtype|Membrane Proteins|*Osteoblasts|Protein Processing, Post-Translational|Protein Transport|Bone Formation|Interferon|Interferon Inducers|Antiviral Agents|Immunoprecipitation|Cysteine|Gene Expression|Influenza, Human|Bone 21 FKBP11 23749938 Anticancer Res. 2013 5 0 0 61 Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|Gnmt protein, mouse|N-Methyltransferase, Glycine|Biomarkers, Tumor|Genes, Tumor Suppressor|RNA, Messenger|Mice, Knockout 21 FLVCR2 23506900 Mol. Aspects Med. 2013 PMC3602793 10.1016/j.mam.2012.07.013 23 16 1 41 Humans|*Heme b|*Membrane Transport Proteins|feline leukemia virus receptor|Receptors, Virus|Erythropoiesis|Posterior column ataxia|Spinocerebellar Degenerations|Retinitis Pigmentosa|Homeostasis|Cell Line|Mutations|Neurodegenerative Disorder|Sensation Disorders|FLVCR1 protein, human|FLVCR2 protein, human 22 FNDC1 24188450 Gynecol. Endocrinol. 2013 10.3109/09513590.2013.850659 10 4 2 16 Humans|Female|Rats|Animals|*Primary Ovarian Insufficiency|*Menopause, Premature|miRNA|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|*Disease Models, Animal|Downregulation|4-vinyl-1-cyclohexene dioxide|Cyclohexenes|Up-Regulation|Vinyl Compounds|Hormone|Apoptosis|FNDC1 protein, human|Neoplasm Proteins|MIRN151 microRNA, rat 29 foxd4 24095780 Gene 2013 10.1016/j.gene.2013.09.090 1 1 0 58 Male|Humans|Child, Preschool|*Mosaicism|*Chromosome Disorders|Chromosome 9p Deletion Syndrome|Chromosome Deletion|Chromosome Inversion|Chromosome Banding|*Genetic Markers|In Situ Hybridization, Fluorescence|*Chromosome 9|Gene Duplication|*Zygotes 27 foxd4 23862097 Am J Stem Cells 2013 PMC3708510 12 0 0 58 Humans|Mice|Animals|*Neural Stem Cells|Neural Plate|Ectoderm|*Nervous System|Xenopus laevis|Neurogenesis|Xenopus Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Transcriptional Activation|*Embryo, Mammalian|Transcriptional Network|Forkhead Transcription Factors 27 FOXI3 24156278 Genome Biol. 2013 PMC4014808 10.1186/gb-2013-14-10-r119 102 6 8 37 Mice|Animals|*Chromatin|Epigenesis, Genetic|*Binding Proteins|5 Methylcytosine|Cytosine|Thymine DNA Glycosylase|DNA Methylation|DNA|Embryonic Stem Cells|Promoter Regions, Genetic|Gene Expression Regulation|Protein Binding|Hydroxylases 30 FOXI3 23441037 Dev. Dyn. 2013 10.1002/dvdy.23952 16 3 2 37 Dogs|Animals|*Ectodysplasins|*Skin|Ectoderm|Wnt Proteins|Hair Follicle|Ectodermal Dysplasia|Hair|Signal Transduction|Membrane Proteins|Gene Expression Regulation, Developmental 30 FOXJ3 23933633 Mol Med Rep 2013 10.3892/mmr.2013.1623 1 1 0 127 Humans|*Rheumatoid Arthritis|Haplotypes|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Genotype|Gene Frequency|Genetic Predisposition to Disease|Autoantibodies|Peptides, Cyclic|Alleles|Asian Continental Ancestry Group|Case-Control Studies|FoxJ3 protein, human|Cell Cycle Proteins|Forkhead Transcription Factors 21 FOXJ3 23299472 Invest. Ophthalmol. Vis. Sci. 2013 PMC3559072 10.1167/iovs.12-10695 8 0 3 127 Humans|*RNA Precursors|*Transcriptome|Alternative Splicing|*Epithelial Cells|Nuclear Proteins|RNA-Binding Proteins|DNA-Binding Proteins|*Transcription Factors|RNA, Messenger|RNA Splicing|*Transcriptome Analysis|Cell Nucleus|Epithelium, Corneal|Cell Adhesion Molecules|ESRP1 protein, human 21 FOXN2 24342142 J. Steroid Biochem. Mol. Biol. 2013 10.1016/j.jsbmb.2013.11.018 33 1 7 138 28 FOXN2 24198246 Nucleic Acids Res. 2013 PMC3919600 10.1093/nar/gkt1040 29 8 3 138 28 GABRG1 24166645 Alcohol Alcohol. 2013 PMC3865816 10.1093/alcalc/agt163 14 0 2 26 *Ethanol|Alcohol Dependence|GABA A Receptor|Alcohol Drinking|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Alleles|Genotype 48 GABRG1 23937595 Ann. Hum. Genet. 2013 10.1111/ahg.12036 15 0 1 26 Humans|Young Adult|Adult|Middle Aged|Aged|Genome-Wide Association Study|*Arabs|*Diabetes Mellitus, Type 2|SNPs|Genetic Predisposition to Disease|*Genome|Genotype|*Extended Family|Case-Control Studies|United Arab Emirates|GABRA2 protein, human|Receptors, GABA-A 48 GAGE1 24232866 Mod. Pathol. 2013 10.1038/modpathol.2013.183 5 0 0 20 Humans|Male|Female|*Testis|Nonseminomatous germ cell tumor|Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Testicular Germ Cell Tumor|Seminoma|MAGEA3 protein, human|Antigens, Neoplasm|Neoplasm Proteins|*Tumorigenesis|*Cell Transformation, Neoplastic|Germinoma|Immunohistochemistry|Spermatogonia|MAGEA4 protein, human 48 GAGE1 23574628 Tissue Antigens 2013 10.1111/tan.12113 23 0 3 20 Male|*Testis|*Cancer Stem Cells|MAGEA3 protein, human|Neoplasm Proteins|Antigens, Neoplasm|Side-Population Cells|MAGEA12 protein, human|*Oncogenes|KDM5B protein, human|Repressor Proteins|Cell Line, Tumor|Adenocarcinoma|CIC protein, human|Genes, Regulator|Lung Adenocarcinoma|Colonic Neoplasms|Immunotherapy|Nuclear Proteins 48 GBX1 24318815 Methods Mol. Biol. 2013 10.1007/978-1-60327-292-6_6 0 0 0 17 Mice|Animals|*Real-Time Polymerase Chain Reaction|Hindbrain|Zebrafish Proteins|Transcription Factors|Mesencephalon|Prosencephalon|Otx Transcription Factors|Zebrafish|Gene Expression Regulation, Developmental|Body Patterning|Trans-Activators|*Gene Expression|Nerve Tissue Proteins|Fibroblast Growth Factors|gbx2 protein, zebrafish|Homeodomain Proteins 34 GBX1 24183937 Dev. Biol. 2013 PMC3935510 10.1016/j.ydbio.2013.10.026 7 17 0 17 Animals|Mice|*Zebrafish|Hindbrain|Zebrafish Proteins|Mesencephalon|Transcription Factors|Otx Transcription Factors|DNA-Binding Proteins|Prosencephalon|Gene Expression Regulation, Developmental|Cerebellum|Wnt1 Protein|Cell Differentiation|Fibroblast Growth Factors|Morphogenesis|gbx2 protein, zebrafish|Homeodomain Proteins 34 GBX1 24010020 PeerJ 2013 PMC3757465 10.7717/peerj.142 4 1 1 17 Mice|Animals|Neurons, Dorsal Horn|Interneurons|Homeodomain Proteins|Horn, Dorsal|*Locomotion|GABAergic Neurons|Transcription Factors|gamma-Aminobutyric Acid|Hindlimbs|Brain 34 GBX1 23418536 PLoS ONE 2013 PMC3572027 10.1371/journal.pone.0056214 6 1 0 17 Mice|Animals|Homeo Box Genes|Homeodomain Proteins|Transcription Factors|Spinal Cord|Gene Expression Regulation, Developmental|Motor Neurons|*Locomotion|In Situ Hybridization|Hindlimb 34 GIMAP4 24257369 Curr Opin Rheumatol 2013 10.1097/BOR.0000000000000003 15 0 4 68 *Studies, Genome-Wide Association|HLA-B51 Antigen|Genetic Susceptibility|Polymorphism, Single Nucleotide|Behcet Syndrome|Minor Histocompatibility Antigens|Alleles|Aminopeptidases|Genotype|Case-Control Studies 29 GLIPR2 24204846 PLoS ONE 2013 PMC3812270 10.1371/journal.pone.0077497 6 17 3 52 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Epithelial-Mesenchymal Transition|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|*Hypoxia|Cell Movement|Hep G2 Cells|Gene Expression Regulation, Neoplastic|*Glioma|Cell Line, Tumor|Cadherins|Signal Transduction|Upregulation 21 GLIPR2 23754683 Mol Med Rep 2013 10.3892/mmr.2013.1516 2 1 0 52 Humans|Male|Animals|Rats|*Thioacetamide|*Oligonucleotide Array Sequence Analysis|Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Liver|Upregulation|Cell Proliferation|Real-Time PCR, Quantitative|Carcinogenesis|Downregulation 21 GLIPR2 23516513 PLoS ONE 2013 PMC3596275 10.1371/journal.pone.0058574 7 16 2 52 Humans|Adult|*MAP Kinase Signaling System|*Epithelial-Mesenchymal Transition|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|CDH1 protein, human|E Cadherin|Kidney Tubules, Proximal|Epithelial Cells|Cell Migration|Fibrosis|Vimentin|Signal Transduction|*Glioma|Diabetic Nephropathy|Kidney|Actins|Cell Line|Antigens, CD 21 GLIPR2 23364696 Nature 2013 PMC3788641 10.1038/nature11866 249 27 12 52 Humans|Mice|Animals|Beclin 1|*Autophagy|Apoptosis Regulatory Proteins|polyglutamine|*Peptides|Membrane Proteins|Human immunodeficiency virus 1|Virus Replication|Peptide Fragments|Chikungunya Fever 21 glycolisis 23994114 Exp. Parasitol. 2013 10.1016/j.exppara.2013.08.015 1 1 1 0 Humans|Animals|*Entamoeba histolytica|incomptine A|Proteomics|Tandem Mass Spectrometry|Sesquiterpenes|Trophozoites|Medicinal Plants|Asteraceae|Dysentery, Amebic|Two Dimensional Gel Electrophoresis|Lactones|Antiprotozoal Agents|Protozoan Proteins|Spectrometry, Mass, Electrospray Ionization|Plant Leaves|Amoebiasis|Plant Extracts|*Phytochemicals 23 GMFB 24155331 J. Cell. Sci. 2013 PMC3874788 10.1242/jcs.140038 18 0 1 125 Humans|*Listeria monocytogenes|*Actins|Cell Surface Extensions|Vacuoles|Shigella flexneri|Cytoplasm|Cytosol|Cell Membrane|Host-Pathogen Interactions|Bacterial Proteins|HeLa Cells 26 GMFB 23333559 Exp. Cell Res. 2013 10.1016/j.yexcr.2013.01.004 4 0 0 125 Animals|*Glia Maturation Factor|*Zebrafish|Endothelial Cells|mRNA|In Situ Hybridization|Cell Movement|Embryonic Development|RNA, Small Interfering|Cell Proliferation|*Morphogenesis|Blotting, Western|Cells, Cultured|Matrix Metalloproteinase 2 26 GOLGA3 23495255 Andrology 2013 PMC4134951 10.1111/j.2047-2927.2013.00070.x 4 4 0 189 Humans|Male|Mice|Animals|*Point Mutation|*Spermatogenesis|Spermatids|Spermatozoa|Spermatocytes|Infertility, Male|Meiosis|Testis|Sperm Count|Epididymis|GOLPH3 protein, human|Membrane Proteins|*Mutation|In Situ Nick-End Labeling|Apoptosis|Golgi Complex 46 GPR179 24222301 Invest. Ophthalmol. Vis. Sci. 2013 10.1167/iovs.13-12610 9 2 0 5 Humans|Night blindness, congenital stationary|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|Retinal Bipolar Cell|Electroretinography|Retina|Mutations|Receptors, Metabotropic Glutamate 25 GPR179 24114537 Invest. Ophthalmol. Vis. Sci. 2013 PMC3813323 10.1167/iovs.13-12907 18 2 0 5 Humans|Animals|*Retina|Retinal Bipolar Cells|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|Night blindness, congenital stationary|Night Blindness|*Signal Transduction|Receptors, G-Protein-Coupled|Eye Diseases, Hereditary|Rod Photoreceptors|Synaptic Transmission|Genetic Diseases, X-Linked|Dendrites|TRPM Cation Channels|Myopia|*Macromolecular Complexes 25 GPR179 24084093 Invest. Ophthalmol. Vis. Sci. 2013 PMC3808102 10.1167/iovs.13-12293 1 0 0 5 Humans|Mice|Animals|Night blindness, congenital stationary|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|*Retina|Retinal Bipolar Cells|Electroretinography|Dark Adaptation|*Disease Models, Animal|Mutations|Receptors, Metabotropic Glutamate|GPR179 protein, mouse|Receptors, G-Protein-Coupled 25 GPR179 23714322 Ophthalmology 2013 10.1016/j.ophtha.2013.03.002 29 2 5 5 Humans|Night blindness, congenital stationary|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|*Phenotype|*Genotype|Electroretinography|Pedigree|Visual Acuity|Mutation|Genotype-Phenotype Correlations 25 GPR26 23457544 PLoS ONE 2013 PMC3572983 10.1371/journal.pone.0056274 1 8 1 71 Humans|Mice|Animals|Cochlea|Stria Vascularis|Vestibule, Labyrinth|*Morphogenesis|Saccule|Homeobox|Deafness|Hair Cells, Cochlear|Hearing Loss, Sensorineural|Transcription Factors|Hearing|Phenotype 20 GPR64 24252460 Acta Neuropathol Commun 2013 PMC3893540 10.1186/2051-5960-1-66 10 7 1 39 Child|Humans|*Medulloblastoma|Cerebellar Neoplasms|Prognoses|Hedgehog Proteins|ORF74 protein, Human herpesvirus 8|*Receptors, Chemokine|Wnt Proteins|Gene Expression Profiling|*G-Protein-Coupled Receptors|Biomarkers, Tumor|Signal Transduction 28 GPR64 23338946 J. Pathol. 2013 10.1002/path.4170 18 8 3 39 Humans|Male|Female|Mice|Animals|MMP1 protein, human|*Matrix Metalloproteinase 1|PGF protein, human|*Placenta Growth Factor|Sarcoma, Ewing|Bone Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|Cell Line, Tumor|RNA Interference|Cell Movement|Apoptosis|*Sarcoma|Lung Neoplasms|Up-Regulation|Cell Differentiation 28 GPR64 23324130 BMC Cardiovasc Disord 2013 PMC3556327 10.1186/1471-2261-13-4 19 32 4 39 *Muscle, Smooth, Vascular|Myocytes, Smooth Muscle|*Phenotype|Atherosclerosis|Cell Movement|Gene Expression Regulation|Cell Proliferation|MicroRNAs|Signal Transduction|Cells, Cultured|Gene Expression Profiling 28 GPR85 24085298 J. Biol. Chem. 2013 PMC3829182 10.1074/jbc.M113.484568 36 2 2 29 Mice|Animals|*Osteoclasts|*Osteogenesis|Tartrate-Resistant Acid Phosphatase|CTSK protein, human|Cathepsin K|RANK Ligand|Receptor Activator of Nuclear Factor-kappa B|Bone Resorption|NFATC Transcription Factors|Cell Differentiation|Acid Phosphatase|MicroRNAs|Gene Expression Regulation|Macrophage|Isoenzymes|Apoptosis|Gene Expression|Calcitonin Receptor 25 GRIN3B 23886513 Neurosci Biobehav Rev 2013 10.1016/j.neubiorev.2013.07.011 41 0 3 31 *Gene-Environment Interaction|*Depression|Genetic Predisposition to Disease|Serotonin Plasma Membrane Transport Proteins|Depressive Disorder, Major|Polymorphism, Single Nucleotide|*Suicidal Ideation 21 GULP1 23838847 Sci Rep 2013 PMC3707025 10.1038/srep02173 4 3 3 148 Humans|Diabetes Mellitus, Type 2|ferumoxides|*Magnetite Nanoparticles|*Obesity|*Adipocytes|Ferric Compounds|Membrane Proteins 37 GULP1 23443560 Nat Commun 2013 PMC3586722 10.1038/ncomms2540 23 31 4 148 Mice|Animals|*Phagocytosis|G-protein-coupled receptor kinase 6|G-Protein-Coupled Receptor Kinases|rac GTP-Binding Proteins|Signal Transduction|rac1 GTP-Binding Protein|Macrophages|Apoptosis|rho GTP-Binding Proteins|Phagocytes|*Autoimmune Disease|Cell Line|Git1 protein, mouse|Cell Cycle Proteins|GTPase-Activating Proteins 37 GULP1 23415435 J Clin Lipidol 2013 10.1016/j.jacl.2012.02.006 3 4 0 148 *Phosphotyrosine|*Cholesterol|*Niemann Pick's Disease Type B|Niemann-Pick Diseases|Sphingomyelins|ATP Binding Cassette Transporter 1|Lipoproteins, HDL|*Fibroblasts|Sphingomyelin Phosphodiesterase|ATP-Binding Cassette Transporters|Endosomes|Lysosomes|Cells, Cultured 37 GULP1 23397585 Arch. Toxicol. 2013 10.1007/s00204-013-1018-4 2 0 1 148 Animals|Thyroid Dyshormonogenesis 4|*Transcriptome|Iodide Peroxidase|iodothyronine deiodinase type I|Thyroxine|Triiodothyronine|Thyroid Hormones|Thyroid Gland|RNA, Messenger|Upregulation 37 HES2 24015274 PLoS ONE 2013 PMC3755970 10.1371/journal.pone.0072767 9 2 0 67 Male|Mice|Animals|*Testis|*Spermatogenesis|Spermatogonia|HES2 protein, human|Transcription Factors|Receptors, Notch|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Signal Transduction|NOTCH3 protein, human|Receptor, Notch3|*Sex Differentiation|Nrarp protein, mouse|Proteins 55 HES2 23759032 Epigenetics Chromatin 2013 PMC3680319 10.1186/1756-8935-6-17 9 3 3 67 *DNA Methylation|CpG Islands|*DNA|Oligonucleotide Array Sequence Analysis|Genome 55 HMG20B 24227653 Development 2013 10.1242/dev.097642 11 0 0 74 Animals|Mice|*Histones|Transcription Factor|*Endocrine Cells|Cell Differentiation|Repressor Proteins|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|KDM1A protein, human|Histone Demethylases|*Modifications, Histone|Zinc Finger|*Pituitary Gland|*Pituitary Diseases|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Transcriptional Network|HDAC1 protein, human|Histone Deacetylase 1 22 HMGN3 23989986 Ann. Rheum. Dis. 2013 PMC4251181 10.1136/annrheumdis-2012-203114 42 4 5 72 *Genome-Wide Association Study|*Osteoarthritis, Hip|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype 28 HMGN3 23620591 J. Biol. Chem. 2013 PMC3675603 10.1074/jbc.M113.463315 20 0 2 72 Mice|Animals|*High Mobility Group Proteins|HMGN3 protein, human|HMGN|HMGN1|Chromatin|Protein Binding|Amino Acid Sequence|Phenotypes|Hmgn5 protein, mouse|HMGN3 protein, mouse 28 HMX1 24194898 PLoS ONE 2013 PMC3806818 10.1371/journal.pone.0077841 7 0 1 76 Cattle|Animals|Genome-Wide Association Study|DNA Copy Number Variations|*Genome|*Genomics|Pedigree|Genes, Homeobox|Phenotypes|Chromosome Mapping|Homeodomain Proteins|Mutation|Ears, External|Switzerland 47 HMX2 24337411 Oncol. Rep. 2013 PMC3896520 10.3892/or.2013.2927 5 3 1 20 *Head and Neck Cancer|Promoter Regions, Genetic|Carcinoma, Squamous Cell|DNA Methylation|Epigenesis, Genetic|CpG Islands|Genes, Tumor Suppressor|Gene Silencing|Cytoskeletal Proteins|Head and Neck Squamous Cell Carcinoma|Cell Line, Tumor 40 HMX2 24176858 Cell Death Dis 2013 PMC3920936 10.1038/cddis.2013.432 6 0 1 20 Animals|*Zebrafish|*Hair Cells, Auditory|Zebrafish Proteins|PAX2 Transcription Factor|Ear, Inner|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Homeodomain Proteins|Transcription Factors|Fibroblast Growth Factors|In Situ Hybridization|Hindbrain|Organogenesis|Signal Transduction|foxi1 protein, zebrafish|Forkhead Transcription Factors 40 HMX2 23457544 PLoS ONE 2013 PMC3572983 10.1371/journal.pone.0056274 1 8 1 20 Humans|Mice|Animals|Cochlea|Stria Vascularis|Vestibule, Labyrinth|*Morphogenesis|Saccule|Homeobox|Deafness|Hair Cells, Cochlear|Hearing Loss, Sensorineural|Transcription Factors|Hearing|Phenotype 40 HOOK3 23952144 Hemoglobin 2013 10.3109/03630269.2013.818016 1 0 1 276 Humans|Adult|*Fetal Hemoglobin|gamma-Globins|beta-Globins|Thalassemia|beta-Thalassemia|Cell Disease, Sickle|Cells, Erythroid|Transcription Factor|Gene Expression Regulation|Carrier Proteins|Brazil|hook3 protein, human|Microtubule-Associated Proteins|MIER1 protein, human|Nuclear Proteins 33 HOOK3 23676460 J. Clin. Invest. 2013 PMC3668835 10.1172/JCI67963 72 0 5 276 Humans|DNA Copy Number Variations|Phosphatidylinositol 3-Kinases|*Intestinal Neoplasms|*Neuroendocrine Tumors|*Genomics|Intestine, Small|MTOR protein, human|TOR Serine-Threonine Kinases|High-Throughput Nucleotide Sequencing|Mutation|Signal Transduction|hook3 protein, human|Microtubule-Associated Proteins|MLF1 protein, human|Proteins 33 HOXA6 24184133 Gastroenterology 2013 10.1053/j.gastro.2013.10.056 31 4 4 56 Mice|Animals|*Hepatitis B virus|*DNA Methylation|*Hepatitis B Virus Infection|Hepatocellular Carcinomas|Liver Neoplasms|*Livers|Hepatitis C|Promoter Regions, Genetic 36 HOXA6 24045431 Mol Med Rep 2013 10.3892/mmr.2013.1686 8 0 0 56 Humans|*Chromosomes, Human, Pair 7|*Lung Adenocarcinoma|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Adenocarcinoma|Chromosome Aberrations|Comparative Genomic Hybridization|DNA, Neoplasm|DNA Copy Number Variations|Biomarkers, Tumor|Genes, Homeobox|HOXA10 protein, human|Homeobox A10 Proteins|HOXA4 protein, human|Homeodomain Proteins|FAM20C protein, human|Extracellular Matrix Proteins|Casein Kinase I 36 HOXA6 23820980 Mol. Biotechnol. 2013 10.1007/s12033-013-9682-4 18 0 2 56 Humans|*Genes, Homeobox|Homeodomain Proteins|Gene Expression Regulation, Neoplastic|Transcription Factors|Cell Transformation, Neoplastic|Gene Expression|Tumors 36 HOXA6 23539541 Haematologica 2013 PMC3729901 10.3324/haematol.2012.079012 13 0 0 56 Humans|*Leukemia, Myeloid, Acute|Genes, Homeobox|Myeloid Ecotropic Viral Integration Site 1 Protein|Gene Expression Regulation, Leukemic|Homeodomain Proteins|Proto-Oncogene Proteins|Neoplasm Proteins|Gene Expression Profiling|Cell Proliferation 36 hus1b 24098119 PLoS Pathog. 2013 PMC3789782 10.1371/journal.ppat.1003652 18 45 3 18 *DNA Primase|*Herpesvirus 1, Human|DNA Replication|Virus Replication|DNA, Viral|xeroderma pigmentosum group F protein|Single-Stranded DNA-Binding Protein|*DNA Helicases|ATRIP protein, human|*Herpes Simplex|Viral Proteins|Adaptor Proteins, Signal Transducing|Nuclear Proteins|Cell Cycle Proteins|DNA Damage|Ataxia Telangiectasia Mutated Proteins|Carrier Proteins|Checkpoint Kinase 1 32 hus1b 24013428 Cell Cycle 2013 PMC3865008 10.4161/cc.26061 2 0 0 18 Male|Mice|Animals|*Constriction|*Meiosis|rad9 protein|Cell Cycle Proteins|DNA Repair|DNA Breaks, Double-Stranded|DNA Damage|Ataxia Telangiectasia Mutated Proteins|Nuclear Proteins|Exonucleases|Carrier Proteins|Signal Transduction|Germ Cells|*Mammals|Testis 32 IGSF3 24040438 Int J Clin Exp Pathol 2013 PMC3759480 16 3 0 44 Humans|*Carcinoma, Non-Small-Cell Lung|gemcitabine|*Lung Neoplasms|*Deoxycytidine|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Drug Resistance, Neoplasm|MicroRNAs|Cell Line, Tumor|Gene Expression Profiling|mRNA|Biomarkers, Tumor|Antimetabolites, Antineoplastic|*Cell Lineage|Downregulation|Signal Transduction|Cell Survival|Apoptosis 20 IMPG1 23993198 Am. J. Hum. Genet. 2013 PMC3769927 10.1016/j.ajhg.2013.07.018 15 0 1 26 Adult|Humans|Adolescent|*Vitelliform Macular Dystrophy|Bestrophins|*Mutations|Eye Proteins|Chloride Channels|Pedigree|Phenotype|Electrooculogram|Homozygote|Fundus Oculi|Visual Acuity|Tomography, Optical Coherence|BEST1 protein, human 29 INSL4 23994019 Mol. Cell. Endocrinol. 2013 10.1016/j.mce.2013.08.010 12 0 3 17 Humans|Male|Female|Pregnancy|*Relaxin|*Reproduction|Amino Acid Sequence|Insulin|Receptors, G-Protein-Coupled|Ovarian Follicle 45 INSL4 23666970 J. Clin. Endocrinol. Metab. 2013 10.1210/jc.2012-3566 31 0 3 17 *DNA Methylation|*B-DNA|*Thyroid Cancer|Adenocarcinoma, Follicular|Carcinoma, Papillary|Thyroid Gland|Carcinoma|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Promoter Regions, Genetic|Cell Line, Tumor|RNA, Messenger 45 INSL4 23302396 Reprod Sci 2013 PMC3713646 10.1177/1933719112472735 6 0 0 17 Humans|Female|Pregnancy|*Relaxin|*Placenta Accreta|Receptors, Peptide|Placenta|Matrix Metalloproteinase 9|Receptors, G-Protein-Coupled|Tissue Inhibitor of Metalloproteinase-1|Matrix Metalloproteinase 2|MMPs|INSL4 protein, human|*Intercellular Signaling Peptides and Proteins|Messenger RNA|Insulins|RXFP1 protein, human 45 INSL4 24640559 Ital J Anat Embryol 2013 1 0 0 17 *Solid-Phase Synthesis Techniques|Peptides|Cysteine|Amino Acid Sequence 45 insl6 23994019 Mol. Cell. Endocrinol. 2013 10.1016/j.mce.2013.08.010 12 0 3 28 Humans|Male|Female|Pregnancy|*Relaxin|*Reproduction|Amino Acid Sequence|Insulin|Receptors, G-Protein-Coupled|Ovarian Follicle 40 insl6 23337591 Fertil. Steril. 2013 10.1016/j.fertnstert.2012.12.023 5 0 0 28 Pregnancy|Male|Humans|Female|Animals|Adult|Cryptorchidism|Relaxin|Reproduction|Testis|Leydig Cells|Lactation|Insulin|*Biomarkers|Endocrine System|Germ Cell 40 INSRR 27375681 J Syst Evol 2013 PMC4926259 10.1111/jse.12048 2 1 0 284 Animals|Humans|*DNA, Complementary|INSR protein, human|*Receptor, Insulin|*Arthropods|*RNA Splicing|Alternative Splicing|Isoforms|B-insulin|*Insulin|Base Sequence|Amino Acid Sequence|EGFR protein, human|Epidermal Growth Factor Receptor|*Biotin|Cloning, Molecular|Sequence Analysis, DNA|Antigens, CD|*Brain 86 INSRR 24121506 J. Biol. Chem. 2013 PMC3837130 10.1074/jbc.M113.483172 5 1 0 284 INSR protein, human|insulin receptor-related receptor|*Receptor, Insulin|*Alkali|Protein Structure, Tertiary|Phosphorylation|Insulin|*Complement Factor B|Signal Transduction|Antigens, CD|Hydrogen-Ion Concentration 86 IRGC 23480672 Zoonoses Public Health 2013 10.1111/zph.12045 4 0 0 17 Animals|Humans|*Public Health|*Vector Borne Diseases|Hemorrhagic Fever Virus, Crimean-Congo|West Nile Virus Infection|Hemorrhagic Fever, Crimean|Dengue|Communicable Diseases, Emerging|Hantavirus Infections|Disease Outbreaks|*Governments|Turkey|Germany|Greece|Portugal|Italy|Hungary|Balkans 32 ISL2 23518338 Dev. Biol. 2013 PMC3657195 10.1016/j.ydbio.2013.03.009 0 7 1 74 Mice|Animals|*Zebrafish|*Organogenesis|Zebrafish Proteins|Mesenchyme|Pancreas|Endoderm|Transcription Factor|Islets of Langerhans|Glucagon|Cell Differentiation|Homeodomain Proteins|Gene Expression Regulation, Developmental|Insulin|Exocrine Pancreas|*B-Lymphocytes|Signal Transduction|isl2b protein, zebrafish|LIM-Homeodomain Proteins 55 ISL2 23515023 J. Gen. Virol. 2013 PMC3709636 10.1099/vir.0.051870-0 9 2 1 74 Female|Pregnancy|Humans|*Hepatitis E virus|RNA, Viral|Virus Replication|Genome, Viral|Base Sequence|Capsid Protein|Nucleic Acid Conformation|Replicon|Capsid|ORFs|3' UTRs|Protein Biosynthesis|Africa|Asia 55 ISL2 23504940 J. Comp. Neurol. 2013 10.1002/cne.23326 4 0 0 74 Animals|Chick Embryo|*Motor Neurons|Spinal Cord|Axons|Homeodomain Proteins|Transcription Factors|*Neurons, Efferent|Gene Expression Regulation, Developmental|Cell Differentiation|Roots, Dorsal|*Chickens|Brainstem|Accessory Nerve|Muscle, Skeletal|Cervical Spinal Cord 55 ISM1 24324026 Hum. Reprod. 2013 10.1093/humrep/det411 4 0 0 121 Pregnancy|Male|Female|Mice|Animals|*Culture Media|*Embryo Implantation|Blastocyst Transfer|Embryo Culture Techniques|Blastocyst|Post-implantation Embryo Development|Fertilization in Vitro|Assisted Reproductive Technology|Oocytes|*Embryo, Mammalian|Spermatozoa 26 ISM1 24108218 Hum. Reprod. 2013 10.1093/humrep/det376 10 0 1 121 Pregnancy|Female|Humans|*Birth Weight|*Culture Media|Embryo Culture Techniques|Fertilization in Vitro|Linear Models|Retrospective Studies 26 ITM2C 23745026 World J. Gastroenterol. 2013 PMC3671076 10.3748/wjg.v19.i21.3249 9 0 3 80 Humans|*Transcriptome|*Feasibility Studies|*Rectal Cancer|Neoadjuvant Therapy|Radiotherapy, Adjuvant|Rectum|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Treatment Outcome|Biopsies 27 KLK15 23894413 PLoS ONE 2013 PMC3718828 10.1371/journal.pone.0069097 0 0 0 19 Humans|Male|*DNA Copy Number Variations|KLK15 protein, human|*Kallikrein|*Gene Cluster|Prostate Cancer|Base Sequence|Single Nucleotide Polymorphisms|Haplotypes|Exon|Alleles|DNA Sequencing|Cohort Studies|Humans|Male|*DNA Copy Number Variations|KLK15 protein, human|*Kallikrein|*Gene Cluster|Prostate Cancer|Base Sequence|Single Nucleotide Polymorphisms|Haplotypes|Exon|Alleles|DNA Sequencing|Cohort Studies 53 KLK15 23620432 Prostate 2013 10.1002/pros.22667 4 0 1 19 Humans|Male|KLK15 protein, human|Kallikreins|*Prostate Cancers|Prognosis|Biomarkers, Tumor|mRNA|Gene Expression Regulation, Neoplastic|*Disease Progression|Up-Regulation 53 KLK9 23894413 PLoS ONE 2013 PMC3718828 10.1371/journal.pone.0069097 0 0 0 20 Humans|Male|*DNA Copy Number Variations|KLK15 protein, human|*Kallikrein|*Gene Cluster|Prostate Cancer|Base Sequence|Single Nucleotide Polymorphisms|Haplotypes|Exon|Alleles|DNA Sequencing|Cohort Studies|Humans|Male|*DNA Copy Number Variations|KLK15 protein, human|*Kallikrein|*Gene Cluster|Prostate Cancer|Base Sequence|Single Nucleotide Polymorphisms|Haplotypes|Exon|Alleles|DNA Sequencing|Cohort Studies 36 KLK9 24128681 J. Neuropathol. Exp. Neurol. 2013 PMC4097185 10.1097/NEN.0000000000000007 13 11 2 20 Humans|Mice|Animals|KLK6 protein, human|*Kallikrein B'|*Injury, Spinal Cord|Spinal Cord|*Neuron Degeneration|Neurons|Axons|Signal Transduction|Disease Models, Animal|Neurotoxicity Syndromes 36 KLRC4 24257369 Curr Opin Rheumatol 2013 10.1097/BOR.0000000000000003 15 0 4 16 *Studies, Genome-Wide Association|HLA-B51 Antigen|Genetic Susceptibility|Polymorphism, Single Nucleotide|Behcet Syndrome|Minor Histocompatibility Antigens|Alleles|Aminopeptidases|Genotype|Case-Control Studies|*Studies, Genome-Wide Association|HLA-B51 Antigen|Genetic Susceptibility|Polymorphism, Single Nucleotide|Behcet Syndrome|Minor Histocompatibility Antigens|Alleles|Aminopeptidases|Genotype|Case-Control Studies 24 KLRC4 24064024 Clin. Exp. Rheumatol. 2013 0 0 0 16 Humans|Genome-Wide Association Study|Behcet Syndrome|Immunosuppressive Agents|Prognosis|Disease Progression|Risk Factors|Recurrence|Severity of Illness Index|Biological Factors|Phenotype|Genetic Predisposition to Disease|STAT4 Transcription Factor 24 KLRC4 23633568 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3657824 10.1073/pnas.1306352110 36 0 6 16 *Familial Mediterranean Fever|*Toll-Like Receptor 4|Genome-Wide Association Study|Pyrin|Mutation|Genetic Predisposition to Disease|Heterozygote|Behcet Syndrome|Cytoskeletal Proteins|TNFRSF1A protein, human|Receptors, Tumor Necrosis Factor, Type I|STAT4 Transcription Factor|Turkey 24 KLRC4 23530727 Tissue Antigens 2013 10.1111/tan.12105 1 0 0 16 *Single Nucleotide Polymorphism|*NK Cell Lectin-Like Receptor Subfamily K|*Multiplex Polymerase Chain Reaction|Leukocytes, Mononuclear|DNA Primers|Genotype|Alleles|Haplotypes|DNA 24 KLRC4 23291587 Nat. Genet. 2013 PMC3810947 10.1038/ng.2520 117 3 14 16 Humans|*Genome-Wide Association Study|*Epistasis, Genetic|HLA-B51 Antigen|SNPs|*HLA-B Antigens|Genetic Predisposition to Disease|STAT4 Transcription Factor|Aminopeptidases|Minor Histocompatibility Antigens|Behcet Syndrome|IL23R protein, human|Receptors, Interleukin|Genotypes|Genes, MHC Class I|Ankylosing Spondylitis|Turkey|ERAP1 protein, human 24 LACRT 23769845 Exp. Eye Res. 2013 PMC3844047 10.1016/j.exer.2013.05.020 21 27 4 69 *Proteome|*Tear|*Dry Eye|tear proteins|Eye Proteins|Lipocalin 1|Glycoproteins|Recombinant Proteins|*Lacerations|Mitogens|*Hormone Replacement Therapy 27 LACRT 23640897 J. Biol. Chem. 2013 PMC3689958 10.1074/jbc.M112.436584 19 8 3 69 Animals|Rabbits|Tears|Dry Eye|*Autophagy|Eye Proteins|Glycoproteins|Blotting, Western|Proteome|Corneal Epithelium|Protein Processing, Post-Translational|Acetylation|Saliva 27 LACRT 23504321 J. Biol. Chem. 2013 PMC3636894 10.1074/jbc.M112.422717 12 1 0 69 SDC1 protein, human|*Syndecan-1|*Chondroitin Sulfates|heparanase|*Protein Domains|*Glucuronidase|*Glycosaminoglycans|Heparitin Sulfate|Membrane Glycoproteins|*Binding Site|Epithelial Cell|*Mitogens|Cell Membrane|Cell Line|Protein Binding|*Intercellular Signaling Peptides and Proteins 27 LACRT 23482462 Invest. Ophthalmol. Vis. Sci. 2013 PMC3626314 10.1167/iovs.12-10394 8 2 1 69 Animals|tear proteins|*Monkey|*Acinar Cells|*Eye Proteins|*Lacrimal Apparatus|*Cultured Cells|Tear|Glycoprotein|*Cell Line|Dry Eye|*Secretion|Cytokines 27 LACRT 23425695 Invest. Ophthalmol. Vis. Sci. 2013 PMC3621506 10.1167/iovs.12-11488 9 2 1 69 Humans|Adult|transglutaminase 2|Proteomics|Tear|*Transglutaminases|*GTP-Binding Proteins|Glycoprotein|Eye Proteins|ELISA|Mitogens|*Cell Differentiation 27 LACRT 23422824 Invest. Ophthalmol. Vis. Sci. 2013 PMC3604909 10.1167/iovs.12-10740 3 0 0 69 Humans|Tears|Lacrimal Gland|Dry Eye|Eye Proteins|Glycoproteins|*Mitogens|*Codons|*Open Reading Frames|*Intercellular Signaling Peptides and Proteins|Cells, Cultured 27 LACRT 23308132 PLoS ONE 2013 PMC3540078 10.1371/journal.pone.0053018 12 0 3 69 Humans|*Fusarium|*Keratitis|Eye Infections, Fungal|Fusariosis|*Tears|Aspergillosis|tear proteins|Eye Proteins|Fungal Infections|Zn-alpha-2-glycoprotein|Seminal Plasma Proteins|Proteomics|Mass Spectrometry|LTF protein, human|Lactoferrin|India 27 LHX5 24024588 Dev. Growth Differ. 2013 10.1111/dgd.12074 3 0 0 58 *Genes, Homeobox|*Prosencephalon|*Retina|*Cell Differentiation|LIM-Homeodomain Proteins|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Retinal Pigment Epithelium|Avian Proteins 61 LHX5 23904411 Anat Rec (Hoboken) 2013 10.1002/ar.22744 8 0 2 58 Animals|Mice|*Smell|*Amygdala|Vomeronasal System|Olfactory Pathways|Prosencephalon|Homeodomain Proteins|Gene Expression Regulation, Developmental|Transcription Factors|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Sex Pheromones|Biological Evolution|Mammals|Neurons|Lizards|Lhx9 protein, mouse|LIM-Homeodomain Proteins 61 LHX5 23426517 Sheng Li Xue Bao 2013 0 0 0 58 Animals|*Zebrafish|*Prosencephalon|Zebrafish Proteins|Axons|Neurons|Luminescent Proteins|Confocal Microscopy|Lhx5 protein, zebrafish|Transcription Factors|LIM-Homeodomain Proteins 61 LPHN2 23817466 Oncogenesis 2013 PMC3740285 10.1038/oncsis.2013.15 24 6 7 177 Humans|*Tumor Suppressor Protein p53|Activation, Transcriptional|Promoter Regions, Genetic|Mutation|Transcription Factor|Gene Expression Regulation|Downregulation|Upregulation|Transcriptome|ARID3B protein, human|DNA-Binding Proteins|PRPF40A protein, human|Carrier Proteins 29 LPHN2 23799614 Int. J. Oncol. 2013 10.3892/ijo.2013.1991 6 0 1 177 Humans|*Carcinoma, Non-Small-Cell Lung|*Whole Exome Sequencing|Lung Cancer|*Carcinoma, Squamous Cell|Adenocarcinoma|Mutation|Mutations, Missense|Epithelial Cells 29 LRWD1 23445371 Andrologia 2013 10.1111/and.12077 1 0 0 85 Humans|Male|Mice|Animals|*Sertoli Cell-Only Syndrome|*Risk Factors|Japan|*Single Nucleotide Polymorphisms|Azoospermia|Frequencies, Allele|Asian Continental Ancestry Group|Infertility, Male|Spermatogenesis|Genotype|DNA Mutational Analysis|*Genes, Regulator|Meiosis|Testis|Mutation|Nucleotides|LRWD1 protein, human|Microtubule Proteins 22 LRWD1 23275029 Int J Mol Sci 2013 PMC3565286 10.3390/ijms14010625 3 21 0 85 Male|Humans|*Leucine|*WD40 Repeats|*Factor B|*Testis|Binding Site|Promoter Regions, Genetic|Base Sequence|Chromatin Immunoprecipitation|Transcription Initiation Site|Electrophoretic Mobility Shift Assay|*Genes, Regulator|NF-kappa B|Protein Binding|RNA, Messenger|LRWD1 protein, human|Microtubule Proteins 22 LSG1 23773259 J Paediatr Child Health 2013 10.1111/jpc.12283 7 0 1 94 Infant|Humans|Child, Preschool|*Obesity|Body Mass Index|Weight Gain|Child Development|Odds Ratio 26 LSG1 23436180 Genetics 2013 PMC3632458 10.1534/genetics.112.149104 6 0 1 94 Humans|Animals|*Drosophila|Saccharomyces cerevisiae|Ribosomes|Saccharomyces cerevisiae Proteins|Ribosomal Proteins|RNA, Ribosomal|Export, Nuclear|Cell Nucleus|GTP-Binding Proteins|GTP Phosphohydrolases|Amino Acid Sequence|Nuclear Proteins|Sequence Homology, Amino Acid|Allele|Mutation|Cell Cycle 26 Ly75 23341106 EMBO Mol Med 2013 PMC3598081 10.1002/emmm.201201553 51 8 4 198 Animals|Humans|*Cardiomyopathy, Dilated|*DNA Methylation|*Heart|Zebrafish|Epigenetic|Myocardium|Phenotype|Heart Failure|Genes, Homeobox|HOXB13 protein, human|Homeodomain Proteins 29 MICAL2 23911929 Mol. Cell 2013 PMC4262529 10.1016/j.molcel.2013.06.019 64 12 5 153 Animals|*Methionine Sulfoxide Reductase B|*Actins|*Racemethionine|methionine sulfoxide|*Methionine|*Redox|Selenoprotein|*Macrophage 22 MICAL2 23703922 Obesity (Silver Spring) 2013 PMC3762924 10.1002/oby.20303 11 2 1 153 Humans|*Genome-Wide Association Study|*Uric Acid|*Obesity|*Overweight|Glucose Transport Proteins, Facilitative|Polymorphism, Single Nucleotide|Genotype|Phenotype 22 MIPEP 23844591 BMC Vet. Res. 2013 PMC3750412 10.1186/1746-6148-9-138 2 5 0 43 Dogs|Animals|*Mammary Neoplasms, Animal|Dog Diseases|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Neoplasm Grading 29 MLLT11 23561263 Ecotoxicol. Environ. Saf. 2013 10.1016/j.ecoenv.2013.03.009 3 0 1 143 Animals|Humans|*Okadaic Acid|*Marine Toxins|Shellfish Poisoning|*Oncogenes|Cell Cycle|*Neurons|Genes, cdc|Carcinogens|Cell Line, Tumor|Genes, Regulator|Molluscs|Cell Transformation, Neoplastic|Chromosomal Abnormalities|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins 40 MTX3 23648218 Acta Trop. 2013 10.1016/j.actatropica.2013.04.013 0 0 0 133 Animals|*Bacillus|Phylogeny|India|Culex|Larvae|Bacterial Toxins|Pest Control, Biological|Insecticides|Anopheles|Bacterial Proteins|PCR 21 MYO5C 24339992 PLoS ONE 2013 PMC3858360 10.1371/journal.pone.0082065 7 10 0 604 Humans|Scattering, Small Angle|X-Ray Diffraction|MYO5A protein, human|*Myosin Type V|*Myosin Heavy Chains|Myosins|Protein Structure, Tertiary|Binding Sites|MYO5B protein, human 22 NEUROD4 23570883 Gene Expr. Patterns 2013 10.1016/j.gep.2013.03.004 2 1 0 53 Animals|Chick Embryo|*Transcription Factor|*Chickens|*Nervous System|Avian Proteins|Basic Helix-Loop-Helix Transcription Factors|Neural Crest|Gene Expression Regulation, Developmental|Ganglia|Nerve Tissue Proteins|Ectoderm|In Situ Hybridization|Neurons|Neural Tube|Cell Differentiation 59 Nfkbil1 23953137 J. Autoimmun. 2013 10.1016/j.jaut.2013.07.010 6 5 1 46 Humans|*Alternative Splicing|Serine-Arginine Splicing Factors|Exon|RNA Precursors|*Orthomyxoviridae|Tyrosine Kinase|RNA-Binding Proteins|RNA Splicing|Nuclear Proteins|Protein-Serine-Threonine Kinases|RNA, Messenger|Phosphorylation|Immunoprecipitation|Serine 67 Nfkbil1 23942620 J. Gastroenterol. 2013 10.1007/s00535-013-0866-2 10 0 2 46 Humans|Japan|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Haplotypes|Alleles|Asian Continental Ancestry Group|Case-Control Studies|European Continental Ancestry Group 67 Nfkbil1 23911423 Mol. Immunol. 2013 10.1016/j.molimm.2013.07.006 12 6 3 46 Humans|*Nuclear Factor-Kappab|*Lupus Erythematosus, Systemic|TNFAIP3 protein, human|Tumor Necrosis Factor alpha-Induced Protein 3|Single Nucleotide Polymorphisms|Chinese|*Epistasis, Genetic|Genetic Predisposition to Disease|Genotype|*Signal Transduction|Genome-Wide Association Study|Gene Frequency|DNA-Binding Proteins|Nuclear Proteins|Intracellular Signaling Peptides and Proteins|Alleles|Case-Control Studies|TNIP1 protein, human 67 Nfkbil1 23909556 Genet Test Mol Biomarkers 2013 PMC3816776 10.1089/gtmb.2013.0264 1 0 0 46 Humans|Lymphotoxin-alpha|Tumor Necrosis Factor-alpha|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Alleles|Case-Control Studies|White|Brazil 67 Nfkbil1 23579626 Immunogenetics 2013 PMC3985396 10.1007/s00251-013-0700-2 5 1 1 46 Humans|*Tumor Necrosis Factor-alpha|Haplotypes|HLA-B Antigens|Linkage Disequilibrium|Alleles|Single Nucleotide Polymorphism|Genotypes|Lymphotoxin|Gene Frequency|Major Histocompatibility Complex|Histocompatibility Antigens Class I|Genetic Predisposition to Disease|Histocompatibility Antigens Class II|European Continental Ancestry Group 67 NFX1 24109236 J. Virol. 2013 PMC3838236 10.1128/JVI.02582-13 8 5 0 98 Humans|*Keratinocytes|*Papillomavirus Infections|*Human Papilloma Virus|E6 protein, Human papillomavirus type 16|Oncogene Proteins, Viral|Repressor Proteins|Human papillomavirus 16|Telomerase|Cells, Cultured|mRNA|NFX1 protein, human 45 NPAS1 24092328 Hum. Mol. Genet. 2013 10.1093/hmg/ddt489 12 0 6 55 Genome-Wide Association Study|*Multiple Sclerosis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genomics|deoxyribonuclease B|*Deoxyribonucleases|B Cells 35 NPAS1 23599003 Nucleic Acids Res. 2013 PMC3675461 10.1093/nar/gkt206 9 9 1 55 ARNT protein, human|*Aryl Hydrocarbon Receptor Nuclear Translocator|AHR protein, human|Aryl Hydrocarbon Receptor|Basic Helix-Loop-Helix Transcription Factors|Protein Binding|Cell Line|Dimerization|Neurons|Cell Differentiation 35 OLFML3 24025712 Clin. Cancer Res. 2013 10.1158/1078-0432.CCR-13-1130 75 0 11 48 *Cancer-Associated Fibroblasts|*Prognosis|*Proteome|*Colorectal Cancer|*Colonic Neoplasms|*Gene Expression Profiling|Fibroblasts|Stromal Cells|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 21 OLFML3 23398349 J. Med. Primatol. 2013 PMC3651808 10.1111/jmp.12037 4 0 1 48 Pregnancy|Adult|Female|Humans|Animals|Rats|olfactomedin|*Baboon|Glycoproteins|Extracellular Matrix Proteins|*Uvea|*Retina|*Cornea|*Lens, Crystalline|*Gene Expression|Iris|Eye Proteins|Cytoskeletal Proteins|Amino Acid Sequence|Sclera|Trabecular Meshwork|*Lenses|Nerve, Optic 21 OTOP1 24176858 Cell Death Dis 2013 PMC3920936 10.1038/cddis.2013.432 6 0 1 24 Animals|*Zebrafish|*Hair Cells, Auditory|Zebrafish Proteins|PAX2 Transcription Factor|Ear, Inner|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Homeodomain Proteins|Transcription Factors|Fibroblast Growth Factors|In Situ Hybridization|Hindbrain|Organogenesis|Signal Transduction|foxi1 protein, zebrafish|Forkhead Transcription Factors 23 OTOP1 23536097 J. Neurosci. 2013 PMC6705067 10.1523/JNEUROSCI.4618-12.2013 13 0 1 24 Mice|Animals|*Retinoic Acid|*Vestibule, Labyrinth|Reflex, Vestibulo-Ocular|Semicircular Canals|Otoliths|Vestibular Function Tests|Eye Movements|Rotation|Saccule|Eye 23 oxsr1 24088575 J Transl Med 2013 PMC3850531 10.1186/1479-5876-11-244 7 1 0 594 Swine|Animals|Humans|*Brain Death|*Apoptosis|Donors|Cold Ischemic Time|Caspase 3|Kidney|Liver|Cytokines|Oxidative Stress 38 PAGE4 24263171 Biochim. Biophys. Acta 2013 PMC4086653 10.1016/j.bbadis.2013.11.014 19 2 3 57 Male|Humans|*Prostate|*Transcriptional Activation|Prostate Cancer|*Proteins|Antigens, Neoplasm|Protein Conformation|Phosphorylation|Cell Line, Tumor|PAGE4 protein, human 31 PAGE4 25374899 Am J Clin Exp Urol 2013 PMC4219281 9 1 0 57 Humans|Male|*Prostate|*Reactive Oxygen Species|Prostate Cancer|Benign Prostatic Hyperplasia|Antigens, Neoplasm|Cell Line, Tumor|*Protective Agents|Transcriptional Activation|Oxidative Stress|Proteins|PAGE4 protein, human 31 PALMD 24004915 BMC Genet. 2013 PMC3844358 10.1186/1471-2156-14-76 8 0 0 58 Female|Sheep|Animals|Cattle|*Milk|Lactation|Genotype|Breeding|Phenotype|Quantitative Trait Loci|Alleles|Selection, Genetic|Polymorphism, Single Nucleotide|Genomics 20 PARM1 24085821 Mol. Endocrinol. 2013 PMC3805850 10.1210/me.2013-1097 6 2 0 49 Female|Male|Rats|Animals|*Progesterone|*Prostate|Granulosa Cells|*Androgens|Luteinizing Hormone|Ovulation|Chorionic Gonadotropin|Luteal Cells|Ovary|MUCL1 protein, human|*Mucins|Cell Differentiation|Steroids|AKR1C3 protein, rat|Aldo-Keto Reductase Family 1 Member C3|Multienzyme Complexes 20 PARM1 23904513 Biol. Reprod. 2013 10.1095/biolreprod.113.111260 7 0 1 49 Pregnancy|Female|Cattle|Male|Animals|*Polymorphism, Single Nucleotide|Serpin E2|*Fertilization|*Embryonic Development|*Sperm|Fertility|Blastocyst|Fertilization in Vitro|Pregnancy Rate|Genotype|Allele Frequency|Milk 20 PARP12 24335297 J. Virol. 2013 PMC3911523 10.1128/JVI.03443-13 49 4 2 93 Animals|Horses|*Poly(ADP-ribose) Polymerases|*Virus Replication|Venezuelan equine encephalitis virus|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Interferon|Alphaviruses|Innate Immune Response|Cell Line|RNA 20 pax6a 23549158 Toxicol. Sci. 2013 PMC3663565 10.1093/toxsci/kft081 19 1 2 0 Animals|*Gold|*Zebrafish|*Metal Nanoparticles|Embryo, Nonmammalian|*Organogenesis|Embryonic Development|Particle Size|Gene Expression Regulation, Developmental|*Pigmentation|Behavior, Animal|In Situ Hybridization|*Pigmentation Disorders 32 PCDH11Y 23600975 Ann. N. Y. Acad. Sci. 2013 PMC3752934 10.1111/nyas.12042 7 16 1 45 Humans|Animals|Chromosomes, Human, X|Chromosomes, Human, Y|Chimpanzee|Hominidae|Cadherins 24 pdia2 23991207 PLoS ONE 2013 PMC3753263 10.1371/journal.pone.0073862 6 0 0 61 Mice|Animals|*Mice, Inbred BALB C|*Protein Disulfide-Isomerases|*Autoantibodies|Polyendocrinopathies, Autoimmune|Mice, Knockout|APECED protein|*Transcription Factors|Autoimmune Diseases|Disease Models, Animal|*Autoimmune Pancreatitis|Pancreas|Phenotype|*Stomach 23 pdia2 23898049 J. Lipid Res. 2013 PMC3770079 10.1194/jlr.M036699 8 0 2 61 Infant, Newborn|Humans|Female|Pregnancy|*Pre-Eclampsia|*Receptors, Lipoprotein|*Placentas|*Infant, Small for Gestational Age|*Lipoprotein|*Atherosclerosis|Fetal Blood|Fetus|Umbilical Cord|Prenatal Care|Mothers|Triglycerides|microsomal triglyceride transfer protein|Carrier Proteins|*Phenotype 23 pdia2 23860123 Am. J. Physiol. Endocrinol. Metab. 2013 PMC3761170 10.1152/ajpendo.00147.2013 12 14 0 61 Humans|Mice|Animals|Endoplasmic Reticulum Stress|Insulin-Secreting Cells|Apoptosis|Insulinoma|Endoplasmic Reticulum|Diabetes Mellitus, Type 1|Signal Transduction|siRNA|Diabetes Mellitus, Type 2|Cell Line, Tumor|Gene Expression Regulation|Pancreatic Neoplasms|Cell Proliferation|EDEM1 protein, human|Membrane Proteins 23 pdia2 23782473 World J Surg Oncol 2013 PMC3691597 10.1186/1477-7819-11-143 8 1 1 61 *Carcinoma, Adenosquamous|*Gallbladder Neoplasms|*Gallbladder|*Adenocarcinoma|Squamous Carcinoma|Prognosis|Biomarkers, Tumor|Lymphatic Metastasis|Kaplan-Meier Estimate 23 PDZRN3 23576576 Am. J. Physiol., Cell Physiol. 2013 10.1152/ajpcell.00343.2012 5 3 1 80 Mice|Animals|*3T3-L1 Cells|Adipogenesis|*Cell Differentiation|Adipocytes|STAT5A protein, human|STAT5 Transcription Factor|CCAAT-Enhancer-Binding Protein-beta|STAT5B protein, human|PPAR gamma|CCAAT Enhancer Binding Protein|Transcriptional Activation|Tumor Suppressor Proteins|RNAi|mRNA|Signal Transduction|Mesenchymal Stem Cells|Upregulation|PDZRN3 protein, mouse 26 PGDF 24139944 Prog. Biophys. Mol. Biol. 2013 10.1016/j.pbiomolbio.2013.10.001 25 23 6 0 Vascular Endothelial Growth Factor A|*Angiogenesis Inhibitors|Neovascularization, Pathologic|*Tumor|Angiogenic Peptides|Epidermal Growth Factor|Signal Transduction|Platelet-Derived Growth Factor|Cytokines|Fibroblast Growth Factor|Tumor Microenvironment 49 PGDF 23707755 Biochem. Pharmacol. 2013 PMC3699334 10.1016/j.bcp.2013.05.010 6 14 1 0 Mice|Animals|*Azoxymethane|*Chemical and Drug Induced Liver Injury, Chronic|CHRM3 protein, human|*Receptor, Muscarinic M3|*Signal Transduction|*Liver|Receptor, Muscarinic M1|CASP3 protein, human|Caspase 3|Pilocarpine|Cell Proliferation|Apoptosis|Disease Models, Animal|Fibrosis, Liver|MMP13 protein, human|Matrix Metalloproteinase 13|Fibrosis 49 PHLDB1 24001599 Hum. Mol. Genet. 2013 10.1093/hmg/ddt424 5 0 2 51 Humans|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|*Asians|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|*Chromosome 3|Alleles|Case-Control Studies|*Chromosome Structures|*Chromosomes, Human|Receptors, CXCR5|China|Hongkong|Thailand|PHLDB1 protein, human|Nerve Tissue Proteins|Intracellular Signaling Peptides and Proteins 41 PHLDB1 23733245 Neuro-oncology 2013 PMC3714154 10.1093/neuonc/not051 24 0 2 51 Humans|Aged|*Telomerase|Genome-Wide Association Study|*Glioma|Single Nucleotide Polymorphisms|Brain Neoplasms|Genetic Predisposition to Disease|RTEL1 protein, human|DNA Helicases|Genotype|Case-Control Studies|Risk Factors|Intracellular Signaling Peptides and Proteins 41 PHLDB1 23300798 PLoS ONE 2013 PMC3534108 10.1371/journal.pone.0052864 6 2 1 51 Humans|Genome-Wide Association Study|*Glioma|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|*Chromosome 3|Brain Neoplasms|Haplotypes|*Chromosomes, Human|Asian Continental Ancestry Group|Genotype|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|*Chromosome Structures|Case-Control Studies|Risk Factor|PHLDB1 protein, human 41 PHLDB1 23280628 Genet. Epidemiol. 2013 PMC3670948 10.1002/gepi.21707 22 0 0 51 *Polymorphism, Single Nucleotide|*Genome-Wide Association Study|Case-Control Studies|*Glioma|Brain Neoplasms|Genetic Predisposition to Disease|RTEL1 protein, human|DNA Helicases|Genotype|Cyclin-Dependent Kinase Inhibitor p15|Telomerase|Intracellular Signaling Peptides and Proteins|Risk Factors|Nerve Tissue Proteins|Genes, p16|San Francisco 41 PILRA 24253495 Mol Med Rep 2013 10.3892/mmr.2013.1813 1 2 1 23 *Hepatitis B virus|Yeast Two-Hybrid System|*Proteins|Hepatitis B Surface Antigens|cDNA Library|Protein Interaction Mapping|Plasmids|Cloning, Molecular|Western Blotting|Hepatocytes|Co-Immunoprecipitation|Yeast|DNA-Directed DNA Polymerase|Immunoglobulins 38 PILRA 23302878 J. Virol. 2013 PMC3592154 10.1128/JVI.02982-12 13 3 1 23 Chlorocebus aethiops|Cricetinae|Humans|Animals|*Herpesvirus 1, Human|*Virion|CHO Cells|Cricetulus|UL53 protein, Human herpesvirus 1|*Viral Proteins|TNFRSF14 protein, human|Herpesvirus Entry Mediator|Virus Entry|Herpes Simplex|NECTIN1 protein, human|Nectin-1|Viral Envelope Proteins|Receptors, Virus|Vero Cells|Cell Fusion|Membrane Fusion|Membrane Glycoproteins 38 pkd1l1 24336289 Nature 2013 PMC4073646 10.1038/nature12832 114 8 15 17 Mice|Animals|Hedgehog Proteins|*Cilia|*Calcium Channel|Patched Receptors|Smoothened Receptor|PKD1L2 protein, human|Receptors, G-Protein-Coupled|Signal Transduction|Receptors, Cell Surface|polycystic kidney disease 1 protein|TRPP Cation Channels|Organelles|Pkd2l1 protein, mouse|Pkd2l2 protein, mouse|Membrane Glycoproteins 20 pkd1l1 24336288 Nature 2013 PMC4112737 10.1038/nature12833 173 16 24 17 Humans|Mice|Animals|*Cilia|Hedgehog Proteins|SMO protein, human|Smoothened Receptor|Zinc Finger Protein Gli2|Receptors, G-Protein-Coupled|Kruppel-Like Transcription Factors|*Calcium Signaling|Basal Body|Calcium Channel|Divisions, Cell|*Organelles|PKD1L1 protein, human|Membrane Proteins|Pkd2l1 protein, mouse|Receptors, Cell Surface 20 Pl15 23577162 PLoS ONE 2013 PMC3618293 10.1371/journal.pone.0060802 20 0 4 0 Animals|*Penaeidae|*Intestines|Aquiculture|RNA, Ribosomal, 16S|Bacteria|Gammaproteobacteria|DNA, Bacterial|Sequence Analysis, DNA|Seafood|Larvae 23 Pl15 25141701 Commun. Agric. Appl. Biol. Sci. 2013 0 0 0 0 Animals|*Artemia|*Ponds|Aquaculture|Animal Feed|Diet|Larva 23 PLAC4 24352757 Prenat. Diagn. 2013 10.1002/pd.4300 1 0 0 0 Pregnancy|Female|Humans|*mRNA|*Biological Factors|*Placenta|Maternal-Fetal Exchange|Prenatal Diagnosis|RNA|Gene Expression Profiling|Gene Expression|*Plasma 22 PLAC4 24214739 Prenat. Diagn. 2013 10.1002/pd.4271 3 0 1 0 Pregnancy|Female|Humans|*Down Syndrome|*RNA|*Trisomy|*Alleles|*Single Nucleotide Polymorphism|Prenatal Diagnosis|Gene Frequency|Fetus|RNA, Messenger|Placenta 22 PLAC4 23337725 J. Clin. Endocrinol. Metab. 2013 10.1210/jc.2012-2468 20 0 1 0 Infant, Newborn|Humans|Female|Pregnancy|*Fetal Growth Retardation|*mRNA|*Placenta|*Infant, Small for Gestational Age|Perinatal Death|Biomarkers 22 PLAC4 23312075 Placenta 2013 10.1016/j.placenta.2012.12.009 2 0 0 0 Humans|Female|Pregnancy|*Pre-Eclampsia|Placenta|Trophoblasts|*Upregulation|*Transcriptional Activation|*Hypoxia|mRNA|Cell Hypoxia|Cell Line 22 PLCL1 24363063 Hum. Mol. Genet. 2013 PMC3990159 10.1093/hmg/ddt647 15 13 2 51 Humans|Mice|Animals|*Pierre Robin Syndrome|In Situ Hybridization, Fluorescence|Campomelic Dysplasia|Base Sequence|SOX9 Transcription Factor|Cleft Palate|Phenotype|Intellectual Disability|Translocation, Genetic|SOX9 protein, human|SATB2 protein, human|Transcription Factors|Matrix Attachment Region Binding Proteins|Sox9 protein, mouse 40 PLCL1 23983088 Arthritis Rheum. 2013 PMC3934004 10.1002/art.38137 37 3 3 51 Adult|Humans|Adolescent|*Genome-Wide Association Study|*Dermatomyositis|*Autoimmune Diseases|Genetic Predisposition to Disease|Polymyositis|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Asian Continental Ancestry Group|Alleles|Case-Control Studies|Genotype|European Continental Ancestry Group 40 PPP1R3A 24264575 Mol. Endocrinol. 2013 PMC5426648 10.1210/me.2013-1268 9 5 2 909 Animals|Mice|*Hepatic Glycogen|*Lipid Metabolism|Glycogen|Hepatocytes|Liver|Glycogen Synthase|Blood Glucose|*Homeostasis|Fasting|Postprandial Period|Fatty Liver|Glycogenolysis|Protein Phosphatase 1|Triglycerides|PPP1R3G protein, mouse 40 PPP1R3A 23690473 J. Immunol. 2013 PMC3679246 10.4049/jimmunol.1202830 56 21 1 909 Humans|*T Cells|*Melanoma|Immunotherapy, Adoptive|Lymphocytes, Tumor-Infiltrating|Adoptive Transfer|Antigens, Neoplasm|Epitopes, T-Lymphocyte|Amino Acid Sequence|cDNA Library|Immunodominant Epitopes|Peptides|Mutation|PPP1R3B protein, human|Protein Phosphatase 1 40 PPP1R3A 23564467 Hepatology 2013 PMC3782998 10.1002/hep.26440 34 1 5 909 Male|Humans|Middle Aged|Female|*Non-alcoholic Fatty Liver Disease|*Hispanic|Allele Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Lipase|African Americans|Membrane Proteins|Chondroitin Sulfate Proteoglycans|Adaptor Proteins, Signal Transducing|Obesity|Triglycerides|Nerve Tissue Proteins|Body Mass Index|Lectins, C-Type|Cohort Studies 40 PRSS56 24227917 Mol. Vis. 2013 PMC3820428 8 0 0 17 Humans|Mice|Animals|*Glaucoma, Angle-Closure|Hyperopia, High|*Hyperopia|*Chinese|*Eye Diseases, Hereditary|Microphthalmia|Prss56 protein, mouse|Serine Proteases|Mutations|Membrane Proteins|Phenotype|PRSS56 protein, human 26 PRSS56 23820083 Gene 2013 10.1016/j.gene.2013.06.045 5 0 0 17 *Microphthalmos|Tunisia|Eye|Haplotype|Mutation|Pedigree|Founder Effects|Serine Proteases|Membrane Proteins|Family 26 prune2 24040105 PLoS ONE 2013 PMC3765211 10.1371/journal.pone.0073880 4 16 0 110 Humans|Male|*Endosomes|*Prostate|*Prostate Cancer|Endocytic Vesicles|Endocytosis|Protein Transport|Neoplasm Proteins|*Genes, Regulator|Protein Binding|Upregulation|Transferrin|Biological Transport 34 prune2 23741331 PLoS ONE 2013 PMC3669334 10.1371/journal.pone.0064483 14 28 2 110 Humans|Mice|Animals|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Databases, Genetic|Adipose Tissue|Gene Expression|Gene Expression Regulation|Adipocyte|Genes, Regulator|Real Time PCR|Obesity|Acvr1c protein, mouse|Activin Receptors, Type I 34 prune2 23731771 Chin J Cancer 2013 PMC3870848 10.5732/cjc.013.10069 4 0 1 110 Humans|Female|*Leiomyosarcoma|*Prognosis|Immunohistochemistry|Uterine Neoplasms|Gastrointestinal Stromal Tumors|Retroperitoneal Neoplasms|Biomarkers, Tumor|*Genes, Regulator|*Transcription Factors|Cell Differentiation 34 prune2 23279911 Eur J Med Genet 2013 10.1016/j.ejmg.2012.12.006 12 0 2 110 Child|Humans|*Intellectual Disability|*Syndrome|*Speech Delay|*Epilepsy|Developmental Disabilities|Chromosome Deletion|Comparative Genomic Hybridization|Abnormalities, Multiple|Genotype-Phenotype Correlations|Phenotype 34 PTPRCAP 24203761 Clin Transl Oncol 2013 10.1007/s12094-013-1124-z 8 0 0 34 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Gene Amplification|Comparative Genomic Hybridization|Lymphatic Metastasis|Number, Gene Copy|Chromosome Aberrations|In Situ Hybridization, Fluorescence|Oncogenes|Cell Line, Tumor|*Chromosome Structures 48 PYHIN1 24324648 PLoS ONE 2013 PMC3851760 10.1371/journal.pone.0080941 11 0 1 57 Adult|Humans|*Genome-Wide Association Study|*HLA-C Antigens|Japan|Reproducibility of Results|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Quantitative Trait Loci|European Continental Ancestry Group|Asian Continental Ancestry Group|Immunoglobulin E|Genotype|*Genes, MHC Class I|Case-Control Studies|Asthma|PYHIN1 protein, human|Nuclear Proteins 20 PYHIN1 23666277 Hum. Genet. 2013 PMC3975655 10.1007/s00439-013-1310-7 3 0 0 57 Humans|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Linkage Disequilibrium|*Asthma|Genetic Predisposition to Disease|African Continental Ancestry Group|European Continental Ancestry Group|African Americans|Chromosome Mapping|Genotype|PYHIN1 protein, human|Nuclear Proteins 20 PYHIN1 23606517 Innate Immun 2013 10.1177/1753425913481636 6 13 0 57 Mice|Animals|*Lipopolysaccharides|*Pyrin|*Macrophages|STAT1 protein, human|STAT1 Transcription Factor|Signal Transduction|Myeloid Differentiation Factor 88|NF-kappa B|Nitric Oxide Synthase Type II|Tifab protein, human|TRAF6|Mitogen-Activated Protein Kinases|Interferon-beta|IRF1 protein, human|Interferon Regulatory Factor-1|Tumor Necrosis Factor-alpha|Nitric Oxide|Macrophages, Peritoneal 20 RAPGEF6 24149987 Sci Rep 2013 PMC3805970 10.1038/srep03032 36 13 3 96 Animals|*Artifacts|Protein Kinase A|Cyclic AMP|Second Messenger|Guanine Nucleotide Exchange Factors|erythromycin propionate-N-acetylcysteinate|*Acetylcysteine|3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile|Hydrazones|*Erythromycin|Signal Transduction|Isoxazoles|Insulin Secretion|ESI-05|Sulfones|Benzene Derivatives 25 RASGEF1B 23913759 Am. J. Med. Genet. A 2013 10.1002/ajmg.a.36061 3 0 0 25 Humans|Female|*Pierre Robin Syndrome|*Cleft Palate|Chromosome 4q- Syndrome|*Chromosome Deletion|*Chromosome Disorders|*Phenotype|Comparative Genomic Hybridization|Facies|*Chromosomes, Human, Pair 4|Abnormalities, Multiple|Genotype-Phenotype Correlation 28 RASGEF1B 23894443 PLoS ONE 2013 PMC3716640 10.1371/journal.pone.0069289 4 2 0 25 Humans|*Cytokinesis|*ras Guanine Nucleotide Exchange Factor|HeLa Cells|*Centrosome|*Spindle Apparatus|Protein-Serine-Threonine Kinases|TYRP1 protein, human|*Membrane Glycoproteins|Intracellular Signaling Peptides and Proteins 28 RASGEF1B 23613679 Genomics Inform 2013 PMC3630382 10.5808/GI.2013.11.1.24 2 0 1 25 *Computational Biology|*Exome|*Whole Exome Sequencing|Mutations|Leukemia, Myeloid, Acute|GATA2 protein, human|GATA2 Transcription Factor|Genomics|DNA Copy Number Variations|High-Throughput Nucleotide Sequencing|Single Nucleotide Polymorphism|Personalized Medicine|Software|*Hematologic Neoplasms 28 RAX2 24039741 PLoS ONE 2013 PMC3764181 10.1371/journal.pone.0072123 2 0 0 14 *Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|*Yeast, Dried|*Endocytosis|Diploid Cells|Haploid Cells|Cell Division|Membrane Glycoproteins|Membrane Proteins|Cell Polarity|Green Fluorescent Proteins|Actins|Plasma Membrane|GTPase 25 RAX2 23608319 Fungal Genet. Biol. 2013 PMC3696419 10.1016/j.fgb.2013.04.002 1 1 0 14 *Hyphae|*Candida albicans|Saccharomyces cerevisiae|*Morphogenesis|Saccharomyces cerevisiae Proteins|Cell Polarity|Gene Deletion|Tropisms 25 REG1B 24328148 J. Proteome Res. 2013 PMC3946306 10.1021/pr400422g 15 0 0 24 Humans|Pancreatic Carcinoma|Pancreatic Cancer|*Adenocarcinoma|*Proteomics|*Glycomics|Chromatography, Liquid|Tandem Mass Spectrometry|Early Detection of Cancer|*Pancreatic Juice|Carcinoma, Pancreatic Ductal|Adenocarcinoma, Mucinous|Pancreas|Pancreatitis|Proteome|Biomarkers, Tumor|REG1A protein, human|Lithostathine 36 REG1B 24007603 BMC Cancer 2013 PMC3847832 10.1186/1471-2407-13-404 18 1 0 24 *Cancer Biomarkers|*CA-19-9 Antigen|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|Specificity|Proteomics|Case-Control Studies 36 REG1B 23553156 Am. J. Clin. Nutr. 2013 PMC3628379 10.3945/ajcn.112.048306 32 0 6 24 Child|Humans|Bangladesh|Peru|*Stunting|Nutritional Status|Intestinal Diseases|Risk Factors 36 REG1B 23519454 Cell Tissue Res. 2013 PMC3663985 10.1007/s00441-013-1592-z 21 2 0 24 Humans|REG1A protein, human|*Lithostathine|*Intestinal Mucosa|*Colon|*In Situ Hybridization|*Gene Expression|Colitis, Ulcerative|*Genes, Regulator|Inflammatory Bowel Disease|Paneth Cells|Immunohistochemistry|Gene Expression Profiling|RNA, Messenger|Lectin, C-Type|Up-Regulation|REG4 protein, human|Pancreatitis-Associated Proteins 36 Resp18 23319378 Neurotox Res 2013 10.1007/s12640-013-9375-6 4 4 0 423 *Neurotoxins|regulated endocrine secretory protein 18|*Dopamine|*Nerve Tissue Proteins|6 Hydroxydopamine|1-Methyl-4-phenylpyridinium|Cell Death|Dopaminergic Drugs|Endoplasmic Reticulum Stress|Rotenone|Caspases|Neurons|Molecular Chaperone|Endoplasmic Reticulum|Parkinson Disease|Transcription Factors 23 RHBDF1 23801765 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3710827 10.1073/pnas.1302553110 0 1 5 79 Mice|Animals|ADAM17 protein, human|*ADAM-17|RHBDF2 protein, human|*Carrier Proteins|ADAM Proteins|EGFR protein, human|Receptor, EGF|HBEGF protein, human|Heparin-binding EGF-like Growth Factor|Signal Transduction|Cells, Cultured|kit Ligand|Adam17 protein, mouse|iRhom2 protein, mouse 30 RNF39 23874430 PLoS ONE 2013 PMC3706582 10.1371/journal.pone.0067572 3 1 0 8 Humans|*HIV-1|*Acquired Immunodeficiency Syndrome|Taiwan|CD4 Cell Counts|HIV Infections|Viral Load|*Asian Continental Ancestry Group|*Disease Progression|Genotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Study, Genetic Association|DNA-Binding Proteins|ZNRD1 protein, human|RNF39 protein, human|Immediate-Early Proteins 22 RNF39 23707810 Biochem. Biophys. Res. Commun. 2013 10.1016/j.bbrc.2013.05.064 3 2 0 8 *Type I Interferon|SNPs|Behcet Disease|Genetic Predisposition to Disease|Genotype|Uveitis|Exon 22 SAMSN1 24278465 PLoS ONE 2013 PMC3838348 10.1371/journal.pone.0081905 0 7 3 51 *Glioblastoma|Glioma|Brain Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Survival Analysis|Cell Line, Tumor|Cell Proliferation 25 SAMSN1 23393914 Asian Pac. J. Allergy Immunol. 2013 0 0 0 51 Humans|*Palatine Tonsil|*Spleen|*B Cells|B-Lymphocyte Subsets|Germinal Center 25 SCAF1 24131527 Liver Int. 2013 10.1111/liv.12330 2 0 0 104 Humans|*Hepacivirus|Ribavirin|Interferon-alpha|*Liver Cirrhosis|Interferon alpha-2|Hepatitis C, Chronic|Antiviral Agents|Interleukins|Polyethylene Glycols|Hepatitis C|Viral Load|Genotype|Drug Therapy, Combination|RNA, Viral|IRF3 protein, human|*Interferon Regulatory Factor-3|Phenotype|Polymorphism, Single Nucleotide 28 SCGB1D2 23819652 J Transl Med 2013 PMC3706350 10.1186/1479-5876-11-162 0 1 0 18 Humans|Female|*Up-Regulation|SCGB1D2 protein, human|*Secretoglobins|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|*Prognosis|Mammaglobin B|Neoplasm Proteins|Biomarkers, Tumor|Immunohistochemistry|Uteroglobin|Gene Expression Regulation, Neoplastic|Proteolipids|*Transcriptional Activation|Cell Line, Tumor|Ovary 156 SCRN1 24098497 PLoS ONE 2013 PMC3789693 10.1371/journal.pone.0076421 16 1 1 65 Humans|Female|DNA Copy Number Variations|Comparative Genomic Hybridization|Neoplasm Recurrence, Local|Prognosis|Receptor, ErbB-2|Receptors, Estrogen|Receptors, Progesterone|Gene Expression Profiling|Biomarkers, Tumor|Oligonucleotide Array Sequence Analysis|Signatures, Gene Expression|Disease-Free Survival|*Asian Continental Ancestry Group|SCRN1 protein, human|Nerve Tissue Proteins|HBXIP protein, human|CSDE1 protein, human|DNA-Binding Proteins 21 SCRN1 23829175 Cancer Sci. 2013 10.1111/cas.12228 14 0 1 65 Humans|*Herpesvirus 4, Human|*Stomach Neoplasms|CpG Island|DNA Methylation|Epstein-Barr Virus Infections|Promoter Regions, Genetic|Decitabine|Gene Expression Regulation, Neoplastic|DNA, Neoplasm|Tumor Suppressor Proteins|Gene Silencing|PCR|SCRN1 protein, human|Nerve Tissue Proteins|BCL7A protein, human|Microfilament Proteins|Oncogene Proteins 21 SERPINB7 24207119 Am. J. Hum. Genet. 2013 PMC3824127 10.1016/j.ajhg.2013.09.015 13 0 1 30 Humans|*Palmoplantar Keratosis|*Mutations|*Serine Proteinase Inhibitors|Serpins|Pedigree|Chinese|*Hand Deformities|*Foot Deformities|SERPINB7 protein, human 57 SERPINB7 23840300 PLoS ONE 2013 PMC3688712 10.1371/journal.pone.0063949 9 20 1 30 Humans|*Skin|Keratinocytes|Skin Diseases|Epidermis|Psoriasis|Interleukin-1|Cells, Cultured|RNA, Messenger|Gene Expression|SERPINB7 protein, human|Serpins|GPR87 protein, human|Receptors, Lysophosphatidic Acid 57 SERPINI1 24369324 J Gastrointestin Liver Dis 2013 4 0 0 165 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Genetic Markers|Egypt|alpha-Fetoproteins|Glypicans|Biomarkers, Tumor|Liver Cirrhosis|Gene Expression Regulation, Neoplastic|ROC Curve|RNA, Messenger|Hepatitis C 31 SERPINI1 23825416 J. Neurosci. 2013 PMC6618611 10.1523/JNEUROSCI.1002-13.2013 16 2 3 165 Rats|Animals|*Axons|Nerve Regeneration|Olfactory Mucosa|Olfactory Bulb|Injury, Spinal Cord|Neurons|*Smell|Cultured Cells|Cell Transplantation|Neurogenesis|Dorsal Root Ganglion|Astrocytes|Cocultures|Tgfb2 protein, rat|Transforming Growth Factor beta2 31 SEZ6L 23962679 J Psychiatr Res 2013 10.1016/j.jpsychires.2013.07.021 12 0 2 15 Humans|Schizophrenia|Bipolar Disorder|Biomarkers 21 SEZ6L 23505291 Circ Cardiovasc Genet 2013 10.1161/CIRCGENETICS.112.964254 14 0 1 15 Humans|Female|*Interleukin-6|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Receptors, Interleukin-6|Allele|C-Reactive Protein|*Biomarkers|*Inflammation|Genetic Predisposition to Disease|Linkage Disequilibrium|*Genetic Testing|Gene Frequency|Genotype|Risk Factor|European Continental Ancestry Group|Coronary Heart Disease|BUD13 homolog protein, human|RNA-Binding Proteins 21 SEZ6L 23468663 PLoS Genet. 2013 PMC3585126 10.1371/journal.pgen.1003338 17 1 2 15 Humans|*Genome-Wide Association Study|*RNA Interference|*Cholesterol|*Lipids|Cholesterol, HDL|Cholesterol, LDL|Triglycerides|Coronary Artery Disease|Polymorphism, Single Nucleotide|Phenotype|Genotype|Myocardial Infarction|PAFAH1B1 protein, human|Microtubule-Associated Proteins|1-Alkyl-2-acetylglycerophosphocholine Esterase|TBL2 protein, human|GTP-Binding Proteins 21 SEZ6L 23430253 J. Biol. Chem. 2013 PMC3624435 10.1074/jbc.M112.444703 29 1 4 15 *Aspartic Acid Endopeptidases|*Amyloid Precursor Protein Secretases|*Amyloid beta-Protein Precursor|*Proteomics|*Pancreas|Insulin-Secreting Cells 21 SH3PXD2B 24105366 Eur. J. Hum. Genet. 2013 PMC4023207 10.1038/ejhg.2013.229 10 0 5 105 Humans|Child|Ter Haar syndrome|Craniofacial Abnormalities|Osteochondrodysplasias|*SH3 Domains|Heart Defects, Congenital|*Mutations|Eye Abnormalities|*Syndrome|Homozygote|Abnormalities, Multiple|Musculoskeletal Abnormalities|Developmental Disabilities|Pedigree|Adaptor Proteins, Signal Transducing|*Heart 23 SHROOM2 23912451 Oncogene 2013 10.1038/onc.2013.298 20 4 0 47 Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Esophageal Squamous Cell Carcinoma|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|*Adenocarcinoma|Barrett Esophagus|Carcinoma, Squamous Cell|Cell Line, Tumor|Cell Proliferation|Cell Migration|Gene Expression Regulation, Neoplastic|Phosphorylation|Signal Transduction|RNA Interference 26 SHROOM2 23735614 Cytogenet. Genome Res. 2013 10.1159/000351310 3 0 0 47 Male|Animals|Swine|*Pseudoautosomal Regions|*Transcriptome|Y Chromosome|X Chromosome|Chromosomes, Artificial, Bacterial|Evolution, Molecular|Intron|Sequence Analysis, DNA 26 SLC16A12 23943784 Cancer Prev Res (Phila) 2013 PMC4337829 10.1158/1940-6207.CAPR-13-0034 10 5 1 24 Humans|*DNA Methylation|*Stomach Neoplasms|CpG Island|Promoter Regions, Genetic|Epigenesis, Genetic|H-cadherin|Cadherins|Gastric Mucosa|hydrogen sulfite|Sulfites|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|CDH1 protein, human|Membrane Proteins|Sequence Analysis, DNA|Antigens, CD 24 SLC16A12 23578822 Hum. Mol. Genet. 2013 PMC3723308 10.1093/hmg/ddt175 14 0 2 24 Humans|Rats|Animals|creatine transporter|SLC6A8 protein, human|*Plasma Membrane Neurotransmitter Transport Proteins|*Nerve Tissue Proteins|*Cataract|Creatine|Lens, Crystalline|Mutation|*Glycosuria|Monocarboxylic Acid Transporters|Xenopus laevis|Oocyte|Cells, Cultured|Slc6a8 protein, rat 24 SLC16A12 23459883 Int. J. Biol. Sci. 2013 PMC3584916 10.7150/ijbs.5613 62 35 3 24 Humans|Animals|interferon type III|Interferons|*Antiviral Agents|*Proteins|Tetratricopeptide Repeats|Virus Infections|Hepatitis C virus|Carrier Proteins|Immunity, Innate|Hepatitis C|Host-Pathogen Interactions|Methylation|Fishes 24 SLC16A9 23990105 Hum. Cell 2013 PMC3844819 10.1007/s13577-013-0073-8 16 6 2 89 Humans|Uric Acid|Genome-Wide Association Study|*Gout|Hyperuricemia|*Kidney|Frequencies, Allele|ATP Binding Cassette Transporter, Subfamily G, Member 2|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Renal Excretion|Asian Continental Ancestry Group|ATP-Binding Cassette Transporters|Kidney Tubules, Proximal|Neoplasm Proteins|Mutation, Missense 30 SLC16A9 23712608 Mov. Disord. 2013 10.1002/mds.25507 19 0 1 89 *Parkinson Disease|*Uric Acid|Polymorphism, Genetic|Disease Progression 30 SLC16A9 23534271 Lik. Sprava 2013 0 0 0 89 Humans|Female|*Hyperuricemia|Uric Acid|*General Practitioners|*Gout|*Physicians, Family|Comorbidity|Sex Factors|Risk Factors|Hypertension|Arthritis, Gouty|SLC22A12 protein, human|Organic Anion Transporters|Organic Cation Transport Proteins|SLC2A9 protein, human|Glucose Transport Proteins, Facilitative 30 SLC16A9 23388106 Stem Cell Res Ther 2013 PMC3706837 10.1186/scrt163 2 12 0 89 Humans|Human Induced Pluripotent Stem Cells|Transcription Factor, Oct-4|Pluripotent Stem Cells|Embryonic Stem Cells|Cell Differentiation|Cell Line|mRNA|3-(4-methylphenylsulfonyl)-2-propenenitrile|Sulfones|Nitriles 30 SLC22A9 23607566 Mol. Pharm. 2013 PMC3973437 10.1021/mp3007133 2 5 0 139 Rats|Animals|Cattle|*Rats, Sprague-Dawley|*Biological Transport|Membrane Transport Proteins|ATP Binding Cassette Transporter, Subfamily G, Member 2|ATP-Binding Cassette Transporters|Retinal Pigment Epithelium|*Drug Delivery Systems|Multidrug Resistance-Associated Proteins|ATP Binding Cassette Transporter, Subfamily B, Member 1|Cornea|Sclera|*Hypoxia|Choroid|Slc22a7 protein, rat|Organic Anion Transporters, Sodium-Independent|Slc22a2 protein, rat|Organic Cation Transporter 2 30 SLC25A24 24332718 Structure 2013 PMC3946054 10.1016/j.str.2013.10.018 9 11 1 148 *Calmodulin|*Mitochondria|Mitochondrial Proteins|Antiporters|Calcium-Binding Proteins|Protein Structure, Tertiary|Calcium|*Hippocampus|Amino Acid Sequence|Adenosine Triphosphate|Protein Binding|Sequence Homology, Amino Acid|*Ion Transport 27 SLC25A24 23933412 Gene 2013 10.1016/j.gene.2013.07.048 0 0 0 148 Pregnancy|Female|Humans|*Amniocentesis|*Chromosomes, Human, Pair 1|*Prenatal Diagnosis|Karyotyping|Mosaicism|Comparative Genomic Hybridization|In Situ Hybridization, Fluorescence|Cytogenetic Analysis|Genetic Markers|SLC25A24 protein, human|Calcium-Binding Proteins|Antiporters|Mitochondrial Proteins 27 SLC31A2 24167251 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3831961 10.1073/pnas.1311749110 41 1 1 125 Mice|Animals|*Cisplatin|*Copper|SLC31A1 protein, human|*Copper Transporter 1|Cation Transport Proteins|*Metals|Plasma Membrane|SLC31 Proteins|*Mammals|Amino Acid Sequence|Protein Transport|Ctr1 protein, mouse|CTR2 protein, mouse 28 SLC31A2 23823179 Magnes Res 2013 10.1684/mrh.2013.0339 1 0 0 125 Humans|*Two-Hybrid System Techniques|*Ubiquitin|HEK293 Cells|Saccharomyces cerevisiae|Protein Interaction Mapping|Protein Sorting|Cytoplasmic Membrane|Cation Transport Proteins|Membrane Proteins|Magnesium|Sodium|SPINT2 protein, human|Membrane Glycoproteins|SLC41A1 protein, human|KCP2 protein, human|Hexosyltransferases 28 SLC31A2 23564780 Anticancer Res. 2013 9 1 0 125 Humans|Female|*Carcinoma, Ovarian Epithelial|*Platinum|*Copper|*Ovarian Cancer|Cystadenocarcinoma, Serous|Adenocarcinoma, Clear Cell|Adenocarcinoma, Mucinous|Endometrial Neoplasms|Cisplatin|Paclitaxel|Prognosis|Drug Resistance, Neoplasm|Antineoplastic Combined Chemotherapy Protocols|Neoplasm Staging|Biomarkers, Tumor|Survival Rate 28 SLC31A2 23391749 Int. J. Biochem. Cell Biol. 2013 10.1016/j.biocel.2013.01.018 17 0 1 125 Animals|*Copper Transport Proteins|Cisplatin|Cation Transport Proteins|Copper|Antineoplastic Agents|Cancer|Biological Transport|Homeostasis|*Mammal|SLC31 Proteins|Copper Transporter 1 28 SMPDL3B 24001144 J. Proteome Res. 2013 10.1021/pr4004807 7 0 0 44 *Glycosylphosphatidylinositols|polypeptide C|*Peptides|Amino Acid Sequence|Chromatography, Liquid|Protein Processing, Post-Translational|Membrane Proteins|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Signal Sequence|Cell Membrane|Hydrophobic and Hydrophilic Interactions 23 SMPDL3B 23739238 Kidney Int. 2013 PMC3816123 10.1038/ki.2013.211 35 1 2 44 Child|Humans|*Rituximab|Nephrosis, congenital|*Nephrotic Syndrome|*Calcineurin Inhibitors|*Nephrosis, Lipoid|Antibodies, Monoclonal, Murine-Derived|Immunosuppressive Agents|Antigens, CD20|Prednisone|CABIN1 protein, human|*Adaptor Proteins, Signal Transducing|Remission Induction|Relapse|Drug Administration Schedule|Treatment Outcome|Drug Therapy, Combination 23 SPAG16 23956247 Ann. Rheum. Dis. 2013 10.1136/annrheumdis-2013-204050 15 0 1 28 Humans|*Rheumatoid Arthritis|Synovial Membrane|*Autoantibodies|Matrix Metalloproteinase 3|*Disease Progression|Matrix Metalloproteinase 1|Fibroblasts|Cells, Cultured 28 SPAG16 23907739 Dev. Dyn. 2013 10.1002/dvdy.24024 8 3 1 28 Animals|Humans|Female|*Cilia|*Fallopian Tubes|*Axoneme|STK36 protein, human|*Protein-Serine-Threonine Kinases|Ovum Transport|*Proteins|Oviducts|Epithelium|Microtubules|*Orientation, Spatial 28 SPAG16 23444080 Andrology 2013 10.1111/j.2047-2927.2013.00069.x 4 1 0 28 Male|Mice|Rabbits|Animals|*Spermatids|*Centrioles|*Transcription Factor|Spermatogenesis|Testis|Spermatozoa|Nuclear Proteins|Cell Cycle Proteins|Sperm Flagellum|Phosphoproteins|Spermatozoa Maturation|Amino Acid Sequence|Meig1 protein, mouse 28 SPAG16 23418344 Am. J. Respir. Cell Mol. Biol. 2013 PMC3727877 10.1165/rcmb.2012-0362OC 18 0 0 28 Humans|Male|Animals|Mice|Infant, Newborn|*Cilia|Axonemes|*Sperm|Kartagener Syndrome|Infertility, Male|Microtubule Proteins|Mutations|Mice, Knockout|Phenotypes|Microtubule|Situs Inversus|SPAG6 protein, mouse|SPAG17 protein, mouse 28 SPAG16 26317022 J Biomark 2013 PMC4437386 10.1155/2013/810395 0 0 0 28 Female|Humans|Male|Child|Gender Bias|*Tetranucleotide Repeat|Haplotype|*Cataract|Alleles|Gene Frequency|Genotype|Linkage Disequilibrium|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Lens, Crystalline|*Men|PCR|SPAG16 protein, human|Microtubule-Associated Proteins 28 SPANXA1 23574628 Tissue Antigens 2013 10.1111/tan.12113 23 0 3 37 Male|*Testis|*Cancer Stem Cells|MAGEA3 protein, human|Neoplasm Proteins|Antigens, Neoplasm|Side-Population Cells|MAGEA12 protein, human|*Oncogenes|KDM5B protein, human|Repressor Proteins|Cell Line, Tumor|Adenocarcinoma|CIC protein, human|Genes, Regulator|Lung Adenocarcinoma|Colonic Neoplasms|Immunotherapy|Nuclear Proteins 27 srpx 24190443 J Zhejiang Univ Sci B 2013 PMC3829646 10.1631/jzus.B1300060 3 0 0 33 *Muscular Dystrophy, Duchenne|*Least-Squares Analysis|Gene Expression Profiling|Gene Expression Regulation|Gene Expression|Transcription Factors|Genes, Regulator|Downregulation|Lipid Metabolism 50 srpx 23831613 Brain 2013 10.1093/brain/awt161 8 2 1 33 Humans|Rats|Animals|tubacin|*Hydroxamic Acids|*Anilides|SRPUL protein, human|*Membrane Proteins|SRPX2 protein, human|Nerve Tissue Proteins|*Neoplasm Proteins|Cerebral Cortex|Cell Movement|Tubulin|Microtubules|*Epilepsy|Acetylation|Neurons|Neurogenesis|Mutations 50 srpx 23449887 Mol. Endocrinol. 2013 PMC3607695 10.1210/me.2011-1275 2 5 0 33 Animals|JAK2 protein, human|*Janus Kinase 2|*Binding Protein|STAT5B protein, human|Signal Transducer and Activator of Transcription 5B|Phosphorylation|STAT3 protein, human|STAT3 Transcription Factor|Receptors, Somatotropin|Signal Transduction|Protein Binding|Growth Hormone|SRPUL protein, human|Neoplasm Proteins|Trans-Activators|DNA-Binding Proteins|Cell Line|Membrane Proteins 50 STK17B 24086368 PLoS ONE 2013 PMC3781145 10.1371/journal.pone.0074765 3 1 0 215 Humans|*Thyroid Cancer, Papillary|Thyroid Cancer|Carcinoma, Papillary|Adenocarcinoma, Follicular|Carcinoma|PAX8 Transcription Factor|Proto-Oncogene Proteins c-ret|Paired Box Transcription Factors|Gene Rearrangement|Genotype|Penetrance|PAX8 protein, human 32 STK17B 23651211 Liver Int. 2013 PMC3706555 10.1111/liv.12188 23 14 1 215 *Carcinoma, Hepatocellular|*T Cell Transcription Factor 4|*Liver Neoplasms|*Up-Regulation|*Isoforms|*Transcriptional Activation|Wnt Signaling Pathway|beta Catenin|Cell Proliferation|Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Alternative Splicing 32 STK17B 23398943 Leuk. Res. 2013 10.1016/j.leukres.2013.01.012 5 7 2 215 Humans|*Genes, myb|*Leukemia, Myeloid, Acute|*Apoptosis|Proto-Oncogene Proteins c-bcl-2|Downregulation|U937 Cells|Myeloid Cell Leukemia Sequence 1 Protein|Transcriptional Activation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 32 STK40 24276375 Mol Med Rep 2013 10.3892/mmr.2013.1828 3 2 0 141 Pregnancy|Female|Mice|Animals|*Transcription Factor|*Pre-implantation Embryo Development|Homeodomain Proteins|Preimplantation Embryos|Zygote|Ectoderm|Gene Expression Regulation, Developmental|Protein-Serine-Threonine Kinases|CDX2 Transcription Factor|Cell Lineage|Embryonic Stem Cells|Cell Differentiation|Cell Nucleus|Stk40 protein, mouse 24 STK40 23293024 J. Biol. Chem. 2013 PMC3581428 10.1074/jbc.M112.409433 7 5 1 141 Pregnancy|Female|Mice|Animals|*Respiratory Insufficiency|Lung|Pulmonary Surfactants|*Proteins|*Birth|Cell Differentiation|Pulmonary Alveoli|Cells, Epithelial|Gene Expression Regulation, Developmental|Respiratory Mucosa|Organogenesis|Serine Threonine Kinase|Stk40 protein, mouse 24 STOML1 24247984 J. Physiol. 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Genet. 2013 10.1038/ng.2827 48 0 5 41 Humans|*Psoriasis|CARD Signaling Adaptor Proteins|Chinese|Guanylate Cyclase|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Mutation, Missense|Case-Control Studies|European Continental Ancestry Group|Membrane Proteins|Risk Factors|ERAP1 protein, human|Aminopeptidases|Minor Histocompatibility Antigens|CARD14 protein, human 26 TBX22 23973723 Gene 2013 10.1016/j.gene.2013.08.032 3 0 2 28 Male|Pregnancy|Humans|Female|*Maternal Inheritance|*Abnormalities, Multiple|Amniocentesis|Comparative Genomic Hybridization|Prenatal Diagnosis|Trisomy|Chromosome Deletion|Chromosomes, Human, X|Cytogenetic Analysis|Fetus|*Chromosome Structures|POU3F4 protein, human|POU Domain Factors|POF1B protein, human|Proteins|BRWD3 protein, human|Transcription Factors|ZDHHC15 protein, human 52 TBX22 23649242 Biosci. Biotechnol. Biochem. 2013 10.1271/bbb.121017 2 0 1 28 Humans|Mice|Animals|*Teratogens|Tetrachlorodibenzo-p-dioxin|*Gene Expression Regulation|*Teratogenesis|Receptors, Aryl Hydrocarbon|Retinoic Acid|Fetal Development|*Complement Factor B|RNA, Messenger|3'-(1-butylphosphoryl)adenosine|DLX4 protein, human|Transcription Factors|Homeodomain Proteins 52 TCF15 24038871 Dev. Dyn. 2013 10.1002/dvdy.24033 3 0 2 58 Animals|Somites|Transcription Factor|Mesoderm|Helix-Loop-Helix Motifs|Basic Helix-Loop-Helix Transcription Factors|Body Patterning|Morphogenesis|Gene Expression Regulation, Developmental|*Epithelial-Mesenchymal Transition|Amino Acid Sequence|*Embryonic Development|Signal Transduction|Vertebrate 39 TCF15 23395635 Cell Rep 2013 PMC3607254 10.1016/j.celrep.2013.01.017 30 16 5 58 *Cell Differentiation|Embryonic Stem Cells|Nanog Homeobox Protein|Pluripotent Stem Cells|Germ Layers|Octamer Transcription Factor-3|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Signal Transduction|Transcription Factors 39 TCF15 23300648 PLoS ONE 2013 PMC3534117 10.1371/journal.pone.0052359 4 32 1 58 Animals|*Xenopus laevis|*Muscle Development|Somites|Xenopus Proteins|MyoD Protein|Myogenic Regulatory Factor 5|Myogenic Regulatory Factors|Transcription Factors|Gene Expression Regulation, Developmental|Mesoderm|Basic Helix-Loop-Helix Transcription Factors|Muscle, Skeletal|Morphogenesis|Cell Differentiation 39 TDRD3 23912948 Nat. Neurosci. 2013 PMC3986889 10.1038/nn.3484 55 15 4 132 messenger ribonucleoprotein|*Ribonucleoproteins|DiGeorge Syndrome|Schizophrenia|Chromosome Deletion|TOP3B protein, human|DNA Topoisomerases, Type I|Fragile X Mental Retardation Protein|*Neurodevelopmental Disorders|Abnormalities, Multiple|Neuromuscular Junction|Phenotype 25 TENM3 24183672 Cell Rep 2013 PMC3898612 10.1016/j.celrep.2013.09.045 34 2 2 39 Animals|*Retinal Ganglion Cells|Retina|Zebrafish|Zebrafish Proteins|Visual Pathways|Axons|Dendrites|Animals, Genetically Modified|Gene Expression Regulation, Developmental|Orientation 28 TENM3 23884953 J. Neurosci. 2013 PMC6618674 10.1523/JNEUROSCI.4708-12.2013 31 0 1 39 Mice|Animals|Geniculate Bodies|Superior Colliculus|Visual Pathways|Primary Visual Cortex|Retinal Ganglion Cells|Retina|Nerve Tissue Proteins|Axons|Binocular Vision|Mice, Knockout|Functional Laterality|Brain Mapping 28 TEX19 23674551 Hum. Reprod. 2013 10.1093/humrep/det129 12 0 2 48 Male|Female|Pregnancy|Mice|Animals|*Spermatogenesis|Testis|Spermatozoa|*Placentation|Nuclear Proteins|*Mammals|Gene Deletion|Placenta|Tex19 protein, mouse 20 TEX19 23364048 Hum. Mol. Genet. 2013 PMC3613164 10.1093/hmg/ddt029 18 5 4 48 Pregnancy|Male|Female|Mice|Animals|*Retroelements|*Placenta|*Long Interspersed Nucleotide Elements|*Intrauterine Growth Retardation|DNA Methylation|Germ Line|Trophoblast|Promoter Regions, Genetic|Nuclear Proteins|Gene Expression Regulation, Developmental|mRNA|Testis|Tex19 protein, mouse 20 TICRR 23974705 J. Assoc. Res. Otolaryngol. 2013 PMC3825021 10.1007/s10162-013-0411-2 20 0 5 110 Humans|*Genome-Wide Association Study|*Chromosomes, Human, Pair 2|*Otitis Media with Effusion|*Otitis Media|Genetic Susceptibility|SNPs|Genotype|Genetic Linkage|Linkage Disequilibrium|*Chronic Disease|Genomics|Recurrence|*Exudates and Transudates|TICRR protein, human|Cell Cycle Proteins 29 TICRR 23907533 Science 2013 PMC3898016 10.1126/science.1241530 70 0 2 110 Animals|*Xenopus laevis|Xenopus Proteins|Blastula|*Cell Cycle Proteins|DNA Replication|Cell Cycle|Chk1 Kinase|Embryo, Nonmammalian|RECQL4 protein, human|RecQ Helicases|Embryogenesis|Transcription, Genetic|Gene Expression Regulation, Developmental|Zygotes|*Fibroblast Growth Factors|Cell Nucleus|Cytoplasm|Drf1 protein, Xenopus 29 TICRR 23704573 Science 2013 10.1126/science.1237448 27 2 1 110 Humans|*Replication Origin|*DNA Replication|Cell Cycle Proteins|Binding Protein|DNA-Binding Proteins|Nuclear Proteins|Saccharomyces cerevisiae Proteins|Cyclin-Dependent Kinases|Cell Cycle|TP53 protein, human|Tumor Suppressor Protein p53|Chromatin|Protein Binding|DNA|MTBP protein, human|TICRR protein, human 29 tiprl 23892082 FEBS Lett. 2013 10.1016/j.febslet.2013.07.027 19 3 5 1859 Animals|*Signal Transduction|TOR Serine-Threonine Kinases|Phosphorylation|Mechanistic Target of Rapamycin Complex 1|Protein Phosphatase 2|Intracellular Signaling Peptides and Proteins|*Amino Acids|*Mammals|Saccharomyces cerevisiae|Downregulation|Subunit, Catalytic 34 TLE6 24356439 Nat Commun 2013 PMC3984242 10.1038/ncomms3956 20 20 3 17 Humans|Mice|Animals|*Glioblastoma|Brain Neoplasms|Tumor Initiating Cells|Cell Differentiation|Downregulation|Gene Expression Regulation, Neoplastic|Forkhead Transcription Factors|Nerve Tissue Proteins|Cell Line, Tumor|Astroglias|Cell Transformation, Neoplastic|3'-(1-butylphosphoryl)adenosine|Upregulation|FOXG1 protein, human|Foxg1 protein, mouse 23 TLE6 23990468 J. Biol. Chem. 2013 PMC3829441 10.1074/jbc.M113.461848 7 8 1 17 *Acid Phosphatase|*Osteoclasts|*PAX6 Transcription Factor|tartaric acid|*Tartrates|TNFSF11 protein, human|*RANK Ligand|NFATC Transcription Factors|*DNA-Binding Proteins|Bone Resorption|Tartrate-Resistant Acid Phosphatase|Osteoblasts|Signal Transduction|Macrophages|Bone Marrow Cells|Cell Differentiation|Osteoclastogenesis|Isoenzymes 23 TMEM38B 23771926 J. Clin. Endocrinol. Metab. 2013 PMC3733862 10.1210/jc.2013-1505 43 0 2 37 *Osteogenesis Imperfecta|Type I Collagen|Collagen|Genes, Recessive|Proteoglycans|Extracellular Matrix Proteins|Mutations|Procollagen|Hydroxylation|Extracellular Matrix|*Bone|Molecular Chaperones|Membrane Glycoproteins|Cyclophilins|Prolyl Hydroxylases 25 TMEM38B 23667675 PLoS ONE 2013 PMC3646805 10.1371/journal.pone.0063821 12 1 1 37 Humans|Female|*Genome-Wide Association Study|*Menarche|Japan|Single Nucleotide Polymorphism|Asian Continental Ancestry Group|European Continental Ancestry Group|Age Factors 25 tppp3 23762501 J Tissue Eng 2013 PMC3677358 10.1177/2041731413492741 4 0 0 109 Mice|Animals|*Tissue Engineering|*Transcriptome|Tendon|Tendon Injuries|Tissue Adhesions|Scars|Wound Healing|Transplantation, Homologous|Reconstructive Surgical Procedures|Orthopedic Procedures|Models, Animal|Foot 22 tppp3 23665002 J Proteomics 2013 10.1016/j.jprot.2013.04.037 38 2 12 109 Humans|*Proteomics|*Lung Cancer|PAGE, 2D|*Chronic Obstructive Pulmonary Disease|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Biomarkers, Tumor|Carcinoma, Squamous Cell|Bronchoalveolar Lavage 22 TTC12 23412349 Genet. Mol. Biol. 2013 PMC3571431 10.1590/s1415-47572012000600004 0 0 2 11 Humans|*Dopamine|*Neural Cell Adhesion Molecules|*Gene Cluster|SNPs|Receptors, Dopamine D2|Haplotypes|Genetic Predisposition to Disease|Genotype|Genetic Variation|CD56 Antigen|*Neurotransmission|*Biological Evolution|Case-Control Studies|*Neurogenesis|TTC12 protein, human|Proteins|ANKK1 protein, human|Protein-Serine-Threonine Kinases 24 TTC12 23303482 JAMA Psychiatry 2013 PMC3789525 10.1001/jamapsychiatry.2013.282 0 2 2 11 Humans|*Heroin Dependence|Haplotypes|Linkage Disequilibrium|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|*Neural Cell Adhesion Molecules|Genotype|Receptors, Dopamine D2|European Continental Ancestry Group|Case-Control Studies|Dependence, Opioid|TTC12 protein, human|Proteins|ANKK1 protein, human|Protein-Serine-Threonine Kinases|NCAM1 protein, human|CD56 Antigen 24 TTI2 23956177 Hum. Mutat. 2013 10.1002/humu.22399 10 0 1 57 Humans|*Mutation|Intellectual Disability|Pedigree|Microcephaly|Dwarfism|*Chromosome Structures|High-Throughput Nucleotide Sequencing|Brain 25 txnl1 24201812 Cell Death Dis 2013 PMC3847316 10.1038/cddis.2013.438 12 19 1 480 *Proto-Oncogene Proteins c-akt|*Cathepsin D|Tandem Mass Spectrometry|*Autophagy|MTOR protein, human|TOR Serine-Threonine Kinases|*Signal Transduction|Reactive Oxygen Species|Autophagosomes|Apoptosis|Cell Line, Tumor|Antineoplastic Agents|Thioredoxins 37 txnl1 23362275 J. Biol. Chem. 2013 PMC3591634 10.1074/jbc.M112.418004 10 0 2 480 Hydrogen Peroxide|TXN protein, human|*Thioredoxin|Protein Tyrosine Phosphatases|*Oxidation-Reduction|Neoplasm Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Membrane Proteins|Cell Cycle Proteins|*Liver Regeneration|Cell Line, Tumor|Cysteine|*Reductase|Liver 37 UBAP2L 23443134 Mol. Cell Proteomics 2013 PMC3617341 10.1074/mcp.M112.026633 18 0 1 157 *Acetylglucosamine|*Tandem Mass Spectrometry|*Osteogenesis|*Electrons|*Proteins|*Osteoblast|UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase|N-Acetylglucosaminyltransferases|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Protein Processing, Post-Translational|Amino Acid Sequence|Proteomics|Glycosylation|Phosphorylation|Peptides|Peptide Fragments|*Electron Transport 21 USP29 24125951 Gene 2013 PMC3872986 10.1016/j.gene.2013.10.006 19 0 2 22 Male|Female|Pregnancy|Mice|Animals|Genomic Imprinting|IGF2 protein, human|IGF-2|DNA Methylation|*Gene Expression|Gene Expression Regulation, Developmental|RNA, Long Noncoding|Placentation|Zim1 protein, mouse|Carrier Proteins|Nerve Tissue Proteins 34 VAX2 23669349 Hum. Mol. Genet. 2013 PMC3736873 10.1093/hmg/ddt211 8 3 0 24 Animals|Humans|*Tumor Suppressor Protein p53|*Coloboma|Zebrafish|Zebrafish Proteins|Microphthalmia, syndromic 2|Microphthalmos|Embryo, Nonmammalian|*Optic Disk|Gene Expression Regulation, Developmental|Transcription Factors|Homeodomain Proteins|Animals, Genetically Modified|Xenopus laevis|Cataract|Heart Septal Defects|*Apoptosis|VAX2 protein, human|RNF2 protein, human 164 VAX2 23613853 PLoS ONE 2013 PMC3628982 10.1371/journal.pone.0061445 12 9 4 24 Animals|*Newt|*Lens, Crystalline|Notophthalmus viridescens|Iris|*Transcriptome Analysis|*Gene Expression|Regeneration|Pigment Epithelium of Eye|*Lenses|Gene Expression Regulation|Cell Transdifferentiation|Up-Regulation|Cells, Epithelial 164 VAX2 23555005 PLoS ONE 2013 PMC3598659 10.1371/journal.pone.0059247 4 15 1 24 *Retinal Pigment Epithelium|MITF protein, human|*MITF Transcription Factor|JAG1 protein, human|Jagged-1 Protein|Homeodomain Proteins|Retina|Signal Transduction|Cell Differentiation|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Cell Proliferation|Membrane Proteins 164 VAX2 23322567 Invest. Ophthalmol. Vis. Sci. 2013 PMC3576051 10.1167/iovs.12-10463 10 0 0 24 Humans|*Astigmatism|Genome-Wide Association Study|Cornea|Refractive Error|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Myopia|Corneal Diseases|European Continental Ancestry Group 164 VIPAS39 23918659 Hum. Mol. Genet. 2013 PMC3842178 10.1093/hmg/ddt378 9 1 1 57 Humans|Mice|Animals|Arthrogryposis renal dysfunction cholestasis syndrome|Arthrogryposis|*Endosomes|Cholestasis|Vesicular Transport Proteins|*Mutations|Renal Insufficiency|Heterozygote|Protein Sorting|Phenotypes|Lysosome|Drosophila|VPS33B protein, human|VIPAS39 protein, human|VPS33B protein, mouse 24 WFDC1 23502471 Int J Mol Sci 2013 PMC3634442 10.3390/ijms14036090 11 14 2 69 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|PAX2 Transcription Factor|Paired Box Transcription Factors|PAX8 Transcription Factor|Cell Proliferation|Up-Regulation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|shRNA|Transcriptional Activation|Cell Movement|WFDC1 protein, human|Proteins|PAX2 protein, human 42 WFDC1 23292442 Mol. Biol. Evol. 2013 PMC3603315 10.1093/molbev/mss329 9 0 1 69 Animals|Humans|*Natural Selection|*Reproduction|Seminal Vesicle Secretory Proteins|Evolution, Molecular|*Immunity|Semen|Proteins|Hominidae|Haplotype|Fertility|Single Nucleotide Polymorphisms 42 ZBED3 24283382 J. Intern. Med. 2013 10.1111/joim.12170 7 7 2 98 Humans|*Insulin Resistance|Cross-Sectional Studies|Genome-Wide Association Study|Glucose Tolerance Test|Diabetes Mellitus, Type 2|*Zinc Fingers|Obesity|Body Mass Index|Adipose Tissue|Zinc|ZBED3 protein, human|DNA-Binding Proteins|Transcription Factors 21 ZBED3 23557703 Diabetes 2013 PMC3717852 10.2337/db12-1627 29 12 2 98 Humans|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|*Blood Glucose|Oral Glucose Tolerance Test|Insulin|Single Nucleotide Polymorphisms|Insulin Secretion|Genetic Predisposition to Disease|Insulin-Secreting Cells|Fasting|*Phenotype|Genotype|Glucose|Risk Factors|Finland|TSPAN8 protein, human|Tetraspanins|ZBED3 protein, human 21 ZBED3 23533661 PLoS ONE 2013 PMC3606216 10.1371/journal.pone.0059940 15 1 3 98 Animals|*DNA Transposable Elements|Transposases|Phylogeny|Vertebrates|Evolution, Molecular|Transcription Factors|DNA-Binding Proteins 21 ZC3H14 24081329 Mol. Cell. Biol. 2013 PMC3838004 10.1128/MCB.00887-13 10 2 1 116 *PAB2 Poly(A) Binding Protein|Yeast, Fission|Poly A Binding Proteins|*mRNA|Schizosaccharomyces pombe Proteins|*RNA Stability|*Cell Nucleus|Poly A|Polyadenylation|RNA Precursors|Gene Expression Regulation, Fungal|Saccharomyces cerevisiae|Gene Expression|NAB2 protein, S cerevisiae|RNA-Binding Proteins|Nucleocytoplasmic Transport Proteins|Saccharomyces cerevisiae Proteins|Pab2 protein, S pombe 23 ZDHHC9 24357419 Am. J. Med. Genet. A 2013 10.1002/ajmg.a.36348 7 0 0 61 Humans|Adolescent|Adult|*Phenotype|*Mutation|Intellectual Disability|Genes, X-Linked|Mental Retardation, X-Linked|Pedigree|Sequencing, Next-Generation|Exons|ZDHHC9 protein, human|Acyltransferases 30 ZDHHC9 24248599 Mol. Cell. Biol. 2013 PMC3911504 10.1128/MCB.01248-13 14 2 1 61 Humans|Animals|Schizosaccharomyces pombe|ras Proteins|Schizosaccharomyces pombe Proteins|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Plasma Membrane|Membrane Proteins|Palmitoylation|Signal Transduction|Golgi Apparatus|Acyltransferases|Amino Acid Sequence|Mutations|ZDHHC9 protein, human|RAS1 protein, S cerevisiae 30 ZDHHC9 24127608 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3816481 10.1073/pnas.1317528110 17 2 2 61 *Lipoylation|*Somatostatin|*Interneurons|Neurons|RNA, Micro|Dendrites|Synaptic Plasticity|Hippocampus|mRNA|Bicuculline|Receptor Antagonist, GABA-A|Protein Transport|Signal Transduction 30 zfhx4 24127225 Am. J. Med. Genet. 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Eye Res. 2013 10.1016/j.exer.2012.12.015 21 0 2 140 Animals|Humans|*Myopia|*Refractive Error|Genome-Wide Association Study|Exome|Genetic Predisposition to Disease|Pedigree|Sequence Analysis, DNA|Mutation|European Continental Ancestry Group|*Animal Models|ZNF644 protein, human|Transcription Factors 20 ZNF91 24344927 BMC Genomics 2013 PMC3880147 10.1186/1471-2164-14-899 11 2 3 55 Animals|*Lizard|*Sex Chromosome|Snakes|Sex Determination Processes|Karyotyping|Genome|Evolution, Molecular|Turtle|In Situ Hybridization, Fluorescence|Genomics 26 ABCF2 22982209 J. Photochem. Photobiol. 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Pathol. 2012 10.1038/modpathol.2012.71 9 0 0 143 NES protein, human|*Nestin|*ATP-Binding Cassette Transporters|Prospective Studies|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Nevi|Melanocyte|Immunohistochemistry|AC133 Antigen|Neoplastic Stem Cells|Biomarkers, Tumor|Antigens, CD 33 ABCF2 22294766 Mutagenesis 2012 10.1093/mutage/ger075 67 0 10 143 Humans|*Colorectal Cancer|ABCB6 protein, human|*ATP-Binding Cassette Transporters|multidrug resistance-associated protein 2|Multidrug Resistance-Associated Proteins|Prognosis|5 Fluorouracil|multidrug resistance-associated protein 1|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Colon|ABCC6 protein, human|Rectum|RNA, Messenger|Gene Expression Profiling|Anticancer Agents|*Colonic Neoplasms|*Disease Progression 33 ABCF2 22252987 J. Cell. 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Reprod. 2012 PMC3329192 10.1093/humrep/des064 4 0 1 6 Male|*Testis|*Prostate|*Sperm-Oocyte Interaction|Acrosome|Spermatozoa|Epididymis|Sperm Head|Blotting, Western|Amino Acid Sequence|Genitalia, Male|Membrane Proteins 57 ADAM29 22922091 Cancer Lett. 2012 10.1016/j.canlet.2012.08.019 15 0 1 13 Male|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Testis|*Autoantibodies|Antigens, Neoplasm|Biomarkers, Tumor|Sensitivity and Specificity|Membrane Proteins|Disease, Lung|Protein Microarray 31 ADAM29 22822400 Front Pharmacol 2012 PMC3398411 10.3389/fphar.2012.00140 40 9 2 13 Animals|*Tumor Microenvironment|Tumors|Neoplastic Processes|Neovascularization, Pathologic|Extracellular Matrix|MMP11 protein, human|Matrix Metalloproteinase 11|Metalloendopeptidases|MMP8 protein, human|Matrix Metalloproteinase 8|Cell Proliferation|Apoptosis 31 ADAM7 22822400 Front Pharmacol 2012 PMC3398411 10.3389/fphar.2012.00140 40 9 2 20 Animals|*Tumor Microenvironment|Tumors|Neoplastic Processes|Neovascularization, Pathologic|Extracellular Matrix|MMP11 protein, human|Matrix Metalloproteinase 11|Metalloendopeptidases|MMP8 protein, human|Matrix Metalloproteinase 8|Cell Proliferation|Apoptosis 24 AGAP1 22453919 J. Biol. Chem. 2012 PMC3366823 10.1074/jbc.M111.334458 8 6 0 202 Humans|*Protein Binding|RHOA protein, human|rhoA GTP-Binding Protein|SAR1B protein, human|*Monomeric GTP-Binding Proteins|*Binding Site|GTPase-Activating Proteins|cdc42 GTP-Binding Protein|Amino Acid Sequence|rac1 GTP-Binding Protein|ADP-Ribosylation Factor 1|G Protein|Cell Line|Sequence Homology, Amino Acid|*Catalysis|AGAP1 protein, human 25 ANKRD17 22328336 Eur. J. Immunol. 2012 10.1002/eji.201142125 9 14 1 122 *Signal Transduction|IRF3 protein, human|Interferon Regulatory Factor-3|DEAD Box Protein 58|Sendai virus|Interferon-Induced Helicase, IFIH1|DEAD-box RNA Helicases|Interferon-beta|*Carrier Proteins|Poly I-C|Adaptor Proteins, Signal Transducing|RNA, Viral|PSMD10 protein, human|Proteasome Endopeptidase Complex 24 BARHL1 23225629 Stem Cells 2012 10.1002/stem.1295 7 3 0 73 Mice|Animals|*Embryonic Stem Cells|*Cell Differentiation|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Nerve Tissue Proteins|Cerebellum|Neurons|*Cytoplasmic Granules|Transcription Factors|*Neurogenesis|Gene Expression Regulation, Developmental|Action Potentials|Cell Migration|*Interneurons|*Central Nervous System|En1 protein, mouse|Homeodomain Proteins|Pde1C protein, mouse 35 BARHL1 23193000 Dev. Dyn. 2012 PMC3553268 10.1002/dvdy.23910 13 15 0 73 Mice|Animals|*Auditory Hair Cell|*Cell Differentiation|NeuroD protein|Basic Helix-Loop-Helix Transcription Factors|Organ of Corti|PAX2 Transcription Factor|Nerve Tissue Proteins|*Organogenesis|In Situ Hybridization|Mice, Knockout|Regeneration|Cell Proliferation|Pou4f3 protein, mouse|Homeodomain Proteins|Transcription Factor Brn-3C|Barhl1 protein, mouse|Repressor Proteins 35 BARHL1 23022312 Brain Res. 2012 PMC3482343 10.1016/j.brainres.2012.09.027 7 7 1 73 Mice|Animals|*Hair Cells, Auditory|Organ of Corti|Basic Helix-Loop-Helix Transcription Factors|Ear, Inner|PAX2 Transcription Factor|Cell Differentiation|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|In Situ Hybridization|Viability, Cell|Pou4f3 protein, mouse|Homeodomain Proteins|Transcription Factor Brn-3C|Barhl1 protein, mouse|Repressor Proteins 35 BARHL1 22514301 J. Neurosci. 2012 PMC6703476 10.1523/JNEUROSCI.6239-11.2012 16 0 0 73 Mice|Animals|*Dorsal Root Ganglion|*Neurons, Dorsal Horn|tropomyosin-related kinase-B, human|Receptor, trkB|Sensory Neurons|*Axons|Mechanoreceptors|MAFA protein, human|Maf Transcription Factors, Large|Receptor, trkC|Pacinian Corpuscles|MAFB protein, human|*MafB Transcription Factor|Receptor, trkA|Proto-Oncogene Proteins c-ret|*Lamina IV|Homeodomain Proteins|Gene Expression Regulation, Developmental 35 BARHL1 22307612 Proc. Natl. Acad. Sci. U.S.A. 2012 PMC3277160 10.1073/pnas.1112392109 13 0 3 73 Mice|Animals|*Neurons|LIM-Homeodomain Proteins|Homeodomain Proteins|Transcription Factor|Axons|Interneurons|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Cell Differentiation|Mice, Knockout|Horn, Dorsal|3'-(1-butylphosphoryl)adenosine|Barhl2 protein, mouse|Lhx2 protein, mouse|Barhl1 protein, mouse|Repressor Proteins 35 BARHL1 22279587 PLoS ONE 2012 PMC3261193 10.1371/journal.pone.0030358 55 5 1 73 Mice|Animals|Mechanotransduction, Cellular|Organ of Corti|Basic Helix-Loop-Helix Transcription Factors|Transcription Factor|Cochlea|Homeodomain Proteins|Gene Expression Regulation, Developmental|Outer Hair Cells|Inner Hair Cells|Ear, Inner|Nerve Tissue Proteins|Cell Differentiation|*Neurogenesis|Atoh1 protein, mouse|Pou4f3 protein, mouse|Transcription Factor Brn-3C|Barhl1 protein, mouse|Repressor Proteins 35 BARHL2 23035102 J. Neurosci. 2012 PMC3475408 10.1523/JNEUROSCI.2073-12.2012 14 0 0 57 Animals|Amacrine Cells|Retina|Retinal Ganglion Cells|Transcription Factor|Homeodomain Proteins|Cell Differentiation|Gene Expression Regulation, Developmental|Zebrafish|Nerve Tissue Proteins 30 BARHL2 22307612 Proc. Natl. Acad. Sci. U.S.A. 2012 PMC3277160 10.1073/pnas.1112392109 13 0 3 57 Mice|Animals|*Neurons|LIM-Homeodomain Proteins|Homeodomain Proteins|Transcription Factor|Axons|Interneurons|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Cell Differentiation|Mice, Knockout|Horn, Dorsal|3'-(1-butylphosphoryl)adenosine|Barhl2 protein, mouse|Lhx2 protein, mouse|Barhl1 protein, mouse|Repressor Proteins 30 BARHL2 22234995 Physiol. Genomics 2012 10.1152/physiolgenomics.00072.2011 3 0 1 57 Mice|Humans|Animals|*Glucose Intolerance|*Prognosis|COVID-19|severe acute respiratory syndrome coronavirus 2|Glucose Tolerance Test|Blood Glucose|Insulin Resistance|Diabetes Mellitus, Type 2|Dietary Fats|Biomarkers|Diet, High-Fat|ACSS2 protein, human|Acetate-CoA Ligase|Arfgap1 protein, mouse|GTPase-Activating Proteins 30 BLID 23126626 J. Med. Chem. 2012 10.1021/jm3011349 3 0 0 49 *Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Amyloid beta-Peptides|Structure-Activity Relationships|Peptide Fragments|Molecular Structure|Alzheimer Disease|Protease Inhibitors|Crystallography, X-Ray|Models, Molecular|Stereoisomerism|Brain|Amidines|Permeability|Guanidines|Cell Line 187 BLID 23058884 Bioorg. Med. Chem. Lett. 2012 10.1016/j.bmcl.2012.09.059 0 0 0 49 Pyrrolopyridazine|*TRPV Cation Channels|*Pyrroles|*Pyridazines|Structure-Activity Relationship|Microsomes, Liver|indolizine|Indolizines 187 BLID 23017051 J. Med. Chem. 2012 10.1021/jm300991n 11 0 2 49 Animals|Guinea Pigs|*Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Amyloid beta-Peptides|Alzheimer Disease|*Brain|Peptide Fragments|Structure-Activity Relationships|Molecular Structure|Crystallography, X-Ray|Models, Molecular|Imidazoles|Drug Design|*Serum Amyloid A Protein|Cell Line|Permeability 187 BLID 22589275 Cancer Res. 2012 PMC3354953 10.1158/0008-5472.CAN-11-3603 26 14 4 49 Humans|Child|*Family Relations|Neoplasm Recurrence, Local|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|*Neuroblastoma|ABT-737|Nitrophenols|*Mitochondria|Myeloid Cell Leukemia Sequence 1 Protein|Biphenyl Compounds|bcl-2 Homologous Antagonist-Killer Protein|Sulfonamides|Apoptosis|Apoptosis Regulatory Proteins|Cell Line, Tumor|Antineoplastic Agents|Drug Resistance, Neoplasm|Piperazines 187 BMP2K 23211419 Mol. Cell Proteomics 2012 PMC3567869 10.1074/mcp.M112.020768 21 7 1 204 *Endocytosis|Protein Isoforms|Nerve Tissue Proteins|Membrane Proteins|EPS15 protein, human|Adaptor Proteins, Signal Transducing|Protein Transport|CDH1 protein, human|E Cadherin|Carrier Proteins|Phosphorylation|Exons|Cell Movement|Cell Line|Antigens, CD 23 C2CD4B 23185617 PLoS ONE 2012 PMC3503928 10.1371/journal.pone.0050418 8 3 2 16 *Diabetes Mellitus, Type 2|*Cardiovascular Diseases|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Gene Frequency|Genotype|Risk Factors 24 C2CD4B 22984506 PLoS ONE 2012 PMC3439414 10.1371/journal.pone.0044424 14 5 1 16 Humans|*Insulin|*Fasting|*Glucose|*Insulin, Regular, Human|Blood Glucose|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Diabetes Mellitus, Type 2|Genome-Wide Association Study|Genotype|Alleles|Asian Continental Ancestry Group|Proinsulin|Glucose-6-Phosphatase|Cohort Studies 24 C2CD4B 22885067 Gene 2012 10.1016/j.gene.2012.07.031 1 0 0 16 Humans|Female|*Endometrium|Embryo Implantation|Infertility, Female|Embryo Transfer|Fertilization in Vitro|*Gene Expression|Fertility|Case-Control Studies 24 C5orf42 23169490 Eur. J. Hum. Genet. 2012 PMC3722952 10.1038/ejhg.2012.254 25 0 4 15 Humans|Meckel syndrome type 1|*Arabs|*Genetic Heterogeneity|*Ciliary Motility Disorders|*Polycystic Kidney Diseases|*Encephalocele|*Retinitis Pigmentosa|*Abnormalities, Multiple|Ciliopathy|Mutation|DNA Mutational Analysis|*Genomics|Pedigree|Membrane Proteins|C5orf42 protein, human 24 C5orf42 23012439 J. Med. Genet. 2012 10.1136/jmedgenet-2012-101132 24 2 1 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Canada|Cerebellar Diseases|*Mutations|Cilia|Membrane Proteins|Phenotype|TMEM231 protein, human 24 CARD6 23189134 PLoS ONE 2012 PMC3506582 10.1371/journal.pone.0048724 2 25 0 74 Mice|Swine|Animals|*Staphylococcus aureus|*Hot Temperature|*BALB C Mice|Cytokines|Chemokines|Th2 Cells|*Staphylococcal Infections|Th1 Cells|Inflammasome|Intestinal Mucosa|Immunity, Innate|*Duodenum 30 CDH16 23150719 J. Natl. Cancer Inst. 2012 PMC3502196 10.1093/jnci/djs418 35 0 5 53 Humans|Birt-Hogg-Dube Syndrome|Cancer, Kidney|Carcinoma, Renal Cell|*Mitochondria|*Genes, Tumor Suppressor|Tumor Suppressor Proteins|Proto-Oncogene Proteins|*Cell Respiration|Kidney|Carrier Proteins|Oxidative Stress|FLCN protein, human 48 CDH16 22495376 Appl. Immunohistochem. Mol. Morphol. 2012 10.1097/PAI.0b013e3182444a4e 0 0 0 53 Humans|Male|*Biotin|alpha-methylacyl-CoA racemase|Racemases and Epimerases|Alpha-Methylacyl-CoA Racemase Deficiency|Immunohistochemistry|Urothelium|Prostatic Neoplasms|Diagnosis, Differential|Biomarkers, Tumor|K cadherin|Cadherins|Adenoma|Adenocarcinoma|Neprilysin|Lipid Metabolism, Inborn Errors 48 CDH16 22455881 Zhonghua Bing Li Xue Za Zhi 2012 2 0 0 53 *Carcinoma, Renal Cell|Kidney Neoplasms|Adenoma, Oxyphilic|Keratin-7|*Immunophenotyping|Immunohistochemistry|Biomarkers, Tumor|Diagnosis, Differential|Vimentin|Prognosis|Neprilysin 48 CDH19 23146407 Cancer Genet 2012 10.1016/j.cancergen.2012.09.007 0 6 0 36 Humans|*Comparative Genomic Hybridization|*Homozygote|*Sequence Deletion|*Chondrosarcoma|Genes, p16|Bone Neoplasms|Genes, Retinoblastoma|DNA, Neoplasm|Gene Deletion|*Cadherins|Genome|Genes, cdc|Purine-Nucleoside Phosphorylase 25 CDH22 22394158 J Altern Complement Med 2012 PMC3306582 10.1089/acm.2010.0764 19 0 4 30 Humans|*Genome-Wide Association Study|Republic of Korea|Medicine, Korean Traditional|Body Constitution|Asian Continental Ancestry Group|Phenotype|Risk Factors 26 CECR2 23112755 Mol Syndromol 2012 PMC3473349 10.1159/000341632 1 0 0 63 Humans|Female|Schmid-Fraccaro syndrome|*Coloboma|*Chromosome Disorders|*Aneuploidy|*Eye Abnormalities|*Chromosomes, Human, Pair 22|Karyotyping|*Genetic Marker|Tetrasomy|Trisomy|Abnormalities, Multiple|Phenotypes|In Situ Hybridization, Fluorescence|Mosaicism|Syndrome|Cecr2 protein, human|Transcription Factors 32 CECR2 22699752 Mol. Cells 2012 PMC3887775 10.1007/s10059-012-0112-4 9 3 1 63 Humans|DNA Breaks, Double-Stranded|Transcription Factors|Nucleosomes|Histones|Nuclear Proteins|DNA Helicases|DNA Repair|Chromatin|Chromatin Assembly and Disassembly|Acetylation|DNA-Binding Proteins|DNA Damage|Phosphorylation|*Protein Domains|Cecr2 protein, human 32 CECR2 22395867 Eur. J. Hum. Genet. 2012 PMC3421127 10.1038/ejhg.2012.43 6 0 1 63 Humans|Schmid-Fraccaro syndrome|*Chromosome Disorders|*Aneuploidy|*Eye Abnormalities|*Chromosome 22|Van der Woude syndrome|Abnormalities, Multiple|Coloboma, Ocular|Karyotyping|Phenotype|Genetic Markers|In Situ Hybridization, Fluorescence|Cleft Lip|Cleft Palate|Anal Atresia|Cysts|Lip|Cecr2 protein, human 32 CEND1 23131156 CNS Neurol Disord Drug Targets 2012 10.2174/1871527311201070829 2 0 0 30 Mice|Animals|*Parkinson Disease|Oxidopamine|Corpus Striatum|*Neural Stem Cells|Substantia Nigra|*Disease Models, Animal|Dopamine|Apomorphine|Transgenic Mouse|Mesencephalon|Tyrosine 3-Monooxygenase|Dopaminergic Neurons|Green Fluorescent Proteins|Nerve Tissue Proteins|Cells, Glial|*Phenotypes|Cend1 protein, mouse|Membrane Proteins 26 CFDP1 23152477 Circ Cardiovasc Genet 2012 10.1161/CIRCGENETICS.112.963660 21 0 3 43 *Carotid Intima-Media Thickness|*Coronary Artery Disease|BCAR1 protein, human|*Crk-Associated Substrate Protein|Atherosclerosis|Carotid Artery Diseases|Carotid Arteries|Plaque, Atherosclerotic|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genome-Wide Association Study|Risk Factors|Phenotype 40 CILP2 23119086 PLoS ONE 2012 PMC3485381 10.1371/journal.pone.0048663 23 4 0 28 *Fenofibrate|*Genome-Wide Association Study|Hypolipidemic Agents|Hypertriglyceridemia|*Lipids|Triglycerides|High Density Lipoprotein Cholesterol|APOA1 protein, human|ApoA-I|Hyperlipidemias|Cholesterol, LDL|Genetic Polymorphisms|Gene Frequency|Genotype|Cholesterol|Lipid Metabolism 34 CILP2 23098650 Physiol Res 2012 10.33549/physiolres.932341 8 0 0 28 Male|Humans|Middle Aged|Aged|Female|*Hydroxymethylglutaryl-CoA Reductase Inhibitors|PCSK9 protein, human|Proprotein Convertase 9|LDL Cholesterol|Atorvastatin|Heptanoic Acids|Anticholesteremic Agents|HDL Cholesterol|Hypercholesterolemia|Simvastatin|Dyslipidemia|Pyrroles|Triglycerides|HMGCR protein, human|HMG CoA Reductase|SNPs|Lipids|Genotype 34 CLIC6 22836882 J. Mol. Neurosci. 2012 PMC3622021 10.1007/s12031-012-9850-1 17 12 1 37 Mice|Animals|*Transcriptome|*Cortex, Prefrontal|Stress, Psychological|Hippocampus|Behavior, Animal|*Genetic Backgrounds|Rasd2 protein, mouse|GTP-Binding Proteins|Acvr1c protein, mouse|Activin Receptors, Type I 21 CLMN 22396030 Rapid Commun. Mass Spectrom. 2012 10.1002/rcm.6187 0 0 0 48 *Cations|*Indicators and Reagents|Spectrometry, Mass, Electrospray Ionization|Electron Transport|Amines|Spectroscopy, Fourier Transform Infrared 29 CMPK2 22992777 Mol Med Rep 2012 10.3892/mmr.2012.1082 7 0 0 29 Humans|Young Adult|Aged|*Osteoporosis|Bone Density|*Clustering|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Regulatory Networks|STAT1 protein, human|STAT1 Transcription Factor|Gene Ontology|Monocytes|Suppressor of Cytokine Signaling Proteins|Genes, Regulator|SOCS3 protein, human|Suppressor of Cytokine Signaling 3 Protein|ANKRD28 protein, human|Intracellular Signaling Peptides and Proteins|PLEKHG2 protein, human|Guanine Nucleotide Exchange Factors 21 CMPK2 22916149 PLoS ONE 2012 PMC3423410 10.1371/journal.pone.0042711 5 0 1 29 Humans|Male|Female|*Quantitative Trait Loci|*DNA, Mitochondrial|*Genetic Linkage|Chromosome Mapping|Lod Score|Microsatellites|Polymorphism, Single Nucleotide|Thrombophilia|MRPL37 protein, human|Ribosomal Proteins|Mitochondrial Proteins 21 cornulin 22843116 Int. J. Legal Med. 2012 PMC3578717 10.1007/s00414-012-0747-x 7 0 0 53 Humans|Male|Female|*Proteomics|Saliva|Semen|Body Fluids|Bodily Secretions|Feces|*Mass Spectrometry|Biomarkers|*Science, Forensic|Forensic Medicine|kallikrein-related peptidase 3, human|Prostate Specific Antigen 27 cornulin 22560086 Acta Histochem. 2012 10.1016/j.acthis.2012.04.003 7 0 1 53 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Down-Regulation|Carcinoma, Squamous Cell|Esophagus|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Cell Line, Tumor|Epithelium|Cytoplasm 27 COX6A2 23256146 J. Nutr. 2012 10.3945/jn.112.164038 11 0 1 26 Rats|Animals|*Rats, Zucker|*Niacin|*Obesity|*Skeletal Muscle Fibers|Muscle Fibers, Slow-Twitch|Muscle Fibers, Fast-Twitch|Dietary Supplements|Diet|Acids, Fatty|Oxidative Phosphorylation|*Oxidation-Reduction|*Glycolysis|Muscle, Skeletal|Oxidative Stress|Slc22a5 protein, rat|Solute Carrier Family 22 Member 5|Slc27a1 protein, rat|Fatty Acid-Binding Proteins 24 COX6A2 22592081 J. Hum. Genet. 2012 10.1038/jhg.2012.49 5 0 0 26 Child|Humans|*Cytochrome-c Oxidase Deficiency|Mutation|Mitochondrial Proteins|Electron Transport Complex IV|Exons|Disorders, Mitochondrial|Membrane Proteins|Introns|Carrier Proteins|Substitutions, Amino Acid 24 COX6A2 22386810 Food Chem. Toxicol. 2012 10.1016/j.fct.2012.02.025 13 2 1 26 Mice|Animals|*Carbon Tetrachloride|*Silymarin|*Factor B|*Transcriptome|*Fibrosis, Liver|Livers|*Transcriptome Analysis|Fibrosis|Mice, Transgenic|NF-kappa B|*Cell Nucleus|Downregulation 24 COX6A2 22237054 Toxicol. Lett. 2012 10.1016/j.toxlet.2011.12.013 2 0 0 26 Pregnancy|Female|Humans|Rats|Animals|perfluorooctane sulfonic acid|*Rats, Sprague-Dawley|*Alkanesulfonic Acids|*Fluorocarbons|*Gene Expression Profiling|*Fetus|*Microarray Analysis|Maternal Exposure|Prenatal Exposure Delayed Effects|*Prenatal Care|Environmental Pollutants|Liver|ITM2A protein, human|Membrane Proteins|ACTN3 protein, human|Actinin|MYOZ2 protein, human|Carrier Proteins 24 CPA6 23105115 J. Biol. Chem. 2012 PMC3522286 10.1074/jbc.M112.414094 7 0 2 44 Humans|HEK293 Cells|carboxypeptidase A6, human|Carboxypeptidases A|*Epilepsy|*Mutations|Febrile Seizures|Epilepsy, Focal|Epilepsy, Temporal Lobe|Single Nucleotide Polymorphisms|Brain 24 CRELD1 23040494 Am. J. Hum. Genet. 2012 PMC3484504 10.1016/j.ajhg.2012.08.017 29 0 3 38 Humans|Atrioventricular Septal Defect|*Down Syndrome|*Vascular Endothelial Growth Factor A|Complete atrioventricular septal defect|*Heart Septal Defects|Congenital Heart Defect|fibulin 2|Extracellular Matrix Proteins|Heart Septal Defects, Atrial|Heart Septal Defects, Ventricular|Trisomy|Calcium-Binding Proteins 32 CRELD1 23027870 J. Biol. Chem. 2012 PMC3501080 10.1074/jbc.M112.405050 22 1 2 38 Humans|Animals|*Oxidase|*Endoplasmic Reticulum Stress|*Antioxidants|PDIA3 protein, human|Protein Disulfide-Isomerases|Endoplasmic Reticulum|Redox|Protein Folding|Unfolded Protein Response|Membrane Glycoproteins|Membrane Proteins|Disulfides|HeLa Cells|Oxidative Stress 32 CRELD1 22987595 Am. J. Med. Genet. A 2012 10.1002/ajmg.a.35626 2 0 0 38 Humans|Atrioventricular Septal Defect|*Down Syndrome|*Haplotypes|*Heart Septal Defects|Trisomy|Congenital Heart Defects|Alleles|Study, Genetic Association|Extracellular Matrix Proteins|Amino Acid Sequence|Base Sequence|Polymorphism, Genetic|Cell Adhesion Molecules|CRELD1 protein, human 32 CRELD1 22903836 Am. J. Med. Genet. A 2012 10.1002/ajmg.a.35559 6 0 0 38 Humans|Chromosome 3, monosomy 3p|*Chromosomes, Human, Pair 3|*Chromosome Deletion|Abnormalities, Multiple|Karyotyping|Phenotype|Intellectual Disability|Congenital Heart Defects|In Situ Hybridization, Fluorescence|Syndrome|Chromosome Aberrations|Seizures|*Chromosome Structures 32 CRELD1 22523272 Circ Cardiovasc Genet 2012 PMC3386785 10.1161/CIRCGENETICS.111.960872 20 9 3 38 Humans|*Down Syndrome|*Heart Defects, Congenital|*Modifier Gene|Trisomy|Genetic Predisposition to Disease|Gene Dosage|Cell Adhesion Molecules|Extracellular Matrix Proteins 32 CROCC 23178122 Cell 2012 PMC3582337 10.1016/j.cell.2012.10.038 78 2 4 82 Mice|Animals|*Cilia|Rod Outer Segment|*Retina|Retinal Rod Photoreceptor Cells|Axoneme|Tomography, Electron|Plasma Membranes|Nerve Tissue Proteins|Morphogenesis 32 CROCC 23070519 Cell Cycle 2012 PMC3495820 10.4161/cc.21986 18 0 1 82 Humans|Animals|*Centrioles|nucleic acid probe 1|Centrosomes|Cilia|Cell Cycle Proteins|Microtubule-Associated Proteins|Basal Body|Microtubule-Organizing Centers|Carrier Proteins|Cell Cycle|Organelles|siRNA|*DNA Damage 32 CROCC 22544322 Cell Cycle 2012 10.4161/cc.20278 7 2 1 82 Humans|Chlorocebus aethiops|Animals|Runx3 Protein|Runx Proteins|Core Binding Factor Alpha 2 Subunit|Core Binding Factor Alpha 1 Subunit|Cell Differentiation|COS Cells|Signal Transduction|Protein Binding|Mitosis|Mutation|Cancer|Runx3 protein, human 32 CRTAC1 22281491 Biochem. Biophys. Res. Commun. 2012 10.1016/j.bbrc.2012.01.033 7 1 1 35 *Nogo Receptor 1|Myelin Proteins|Axons|Growth Cones|Myelin-Associated Glycoprotein|Nogo Proteins|Neurons|Dorsal Root Ganglion|Receptors, Cell Surface|Central Nervous System|Protein Binding|GPI-Linked Proteins|Calcium-Binding Proteins|Cells, Cultured|*Cartilage 27 CRYBB3 23073841 Graefes Arch. Clin. Exp. Ophthalmol. 2012 10.1007/s00417-012-2157-7 3 0 0 14 *Retinal Pigment Epithelium|*Crystallin|Blotting, Western|Cells, Cultured|RNA, Messenger|Real-Time Polymerase Chain Reaction 36 CRYBB3 22669729 Mol. Cell. Biochem. 2012 10.1007/s11010-012-1355-2 4 0 0 14 *Mutation, Missense|Cerulean cataract|*Cataract|Cataract, Crystalline Aculeiform|Cataract, zonular|Cataract, Autosomal Dominant|gamma-Crystallins|Genes, Dominant|DNA Mutational Analysis|Pedigree|Connexins|Mutation|Base Sequence|Phenotype|Switzerland 36 CRYBB3 22312185 Mol. Vis. 2012 PMC3272051 12 0 0 14 *Mutation, Missense|beta-Crystallin B Chain|Cataract, Autosomal Dominant|*Cataract|Genes, Dominant|Pedigree|DNA Mutational Analysis|Base Sequence|Genetic Linkage|Mutation 36 CRYZ 22843503 Hum. Mol. Genet. 2012 PMC3471394 10.1093/hmg/dds300 14 1 0 488 Humans|RETN protein, human|*Resistin|*Genome-Wide Association Study|Diabetes Mellitus, Type 2|Single Nucleotide Polymorphisms|Allele|Insulin Resistance|Genotype|Quantitative Trait Loci|Promoter Regions, Genetic 164 CST8 23269664 Biol. Reprod. 2012 10.1095/biolreprod.112.104745 3 0 0 190 Male|*Spermatozoa|*Tails, Sperm|Epididymis|Testis|Spermatids|Spermiogenesis|Cystatins|Electron Microscopy|Western Blots|Proteins|Immunohistochemistry 31 CST8 23185254 PLoS ONE 2012 PMC3504038 10.1371/journal.pone.0048368 8 3 0 190 Mice|Male|Animals|*Epididymis|Escherichia coli|*Spermatogenesis|Testis|Amino Acid Sequence|CST3 protein, human|Cystatin 3|Recombinant Proteins|Cst8 protein, mouse|Cystatins 31 CST8 22827436 Curr. Mol. Med. 2012 10.2174/156652412802480961 1 5 0 190 Humans|Mice|Male|Animals|*Epididymis|*Serpins|Proprotein Convertases|Acrosome Reaction|*Proteolysis|Sperm|Serine Endopeptidases|Subtilisins|Cystatins|Fertilization|Recombinant Proteins|Spermatogenesis|tert-butoxycarbonyl-arginyl-valyl-arginyl-arginyl-methylcoumarin amide|Oligopeptides|Coumarins|Substrate Specificity 31 CST8 22701646 PLoS ONE 2012 PMC3368854 10.1371/journal.pone.0038457 25 5 5 190 Mice|Male|Animals|*Epididymis|DICER1 protein, human|*Ribonuclease III|*DEAD-box RNA Helicases|Spermatogenesis|*Signal Transduction|Spermatozoa|*Gonadal Steroid Hormones|RNA Interference|Gene Expression Regulation, Developmental|MicroRNAs|*Epithelium|Cell Differentiation|Dicer1 protein, mouse 31 CST8 22570708 PLoS ONE 2012 PMC3343081 10.1371/journal.pone.0036394 17 1 1 190 Male|Mice|Animals|*Sperm Maturation|*Epididymis|*Amyloid|*Sperm|*Amyloidogenic Proteins|Cystatin Superfamily|*Amyloidosis|Spermatogenesis|*Organelles|Cst8 protein, mouse 31 DACH2 22700049 J Physiol Sci 2012 10.1007/s12576-012-0214-y 2 0 0 37 Humans|Mice|Animals|Muscle Fibers, Slow-Twitch|Muscle Fibers, Fast-Twitch|*Muscle, Skeletal|*Genes, Homeobox|Muscle Fibers, Skeletal|Transcription Factor|Gene Expression Regulation|SIX1 protein, human|Homeodomain Proteins|Six1 protein, mouse 36 DACH2 22284433 J Ovarian Res 2012 PMC3295641 10.1186/1757-2215-5-6 5 2 1 37 Humans|Female|Mice|Animals|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cisplatin|Drug Resistance, Neoplasm|Prognosis|Cell Line, Tumor|Apoptosis|*Biomarkers 36 DDX25 22479328 PLoS ONE 2012 PMC3316541 10.1371/journal.pone.0032470 8 11 0 41 Male|Mice|Animals|*Testis|*mRNA|*Polysomes|Spermatogenesis|*Gonadotropin|Leydig Cells|DEAD-box RNA Helicases|Germ Cell|Gene Expression Regulation|Mice, Knockout|Up-Regulation|Ddx25 protein, mouse 39 DDX25 22331472 Mol. Cell. Biol. 2012 PMC3318589 10.1128/MCB.06002-11 7 0 0 41 Male|*Testis|*Gonadotropin|Spermatogenesis|Leydig Cells|DEAD-box RNA Helicases|Androgens|Germ Cells|Gene Expression Regulation|Receptors, Androgen|Androgen Receptor Antagonists|Promoter Regions, Genetic|Activation, Transcriptional|Response Elements 39 DEXI 23251452 PLoS ONE 2012 PMC3520980 10.1371/journal.pone.0051203 18 3 1 27 *Leukemia, Myeloid, Acute|Karyotyping|Cytogenetic Analysis|Chromosome Aberrations|MHC class II transactivator protein|Nuclear Proteins|Transcriptome Analysis|Karyotype 30 DGCR2 22465717 J Proteomics 2012 10.1016/j.jprot.2012.03.008 21 0 4 182 Humans|*Insulin-Secreting Cells|*Proteomics|Islet Cell|Glucagon|Insulin|Diabetes Mellitus, Type 1|*Antibodies|*Biomarkers|Diabetes Mellitus, Type 2|Pancreas|TYRP1 protein, human|*Membrane Glycoproteins|Blotting, Western 22 DGCR2 22407589 Am. J. Med. Genet. A 2012 10.1002/ajmg.a.34133 9 0 1 182 Humans|Male|Barakat syndrome|Hypoparathyroidism|Nephrosis|Hearing Loss, Sensorineural|GATA3 protein, human|GATA3 Transcription Factor|DiGeorge Syndrome|Hearing Loss, Bilateral|Kidney Diseases|Phenotype|Gene Deletion|Kidney|Haploinsufficiency 22 DGCR6 22832905 Transl Psychiatry 2012 PMC3337078 10.1038/tp.2012.31 7 2 1 67 Humans|Child|Adult|*DiGeorge Syndrome|Epigenesis, Genetic|*Psychopathology|Genetic Predisposition to Disease|Chromosome Deletion|Shprintzen Golberg craniosynostosis|Arachnodactyly|Marfan Syndrome|Craniosynostoses|Anxiety Disorders|Chromosome|DGCR6 protein, human|Extracellular Matrix Proteins 24 DKKL1 23261660 Brain Res. 2012 PMC3801191 10.1016/j.brainres.2012.12.015 16 41 1 98 Humans|Adult|*Neurodegenerative Diseases|Wnt Signaling Pathway|*Estrogens|Wnt Proteins|beta Catenin|*Catenins|Intercellular Signaling Peptides and Proteins|Oestradiol|Neurons|Hippocampus|Brain Ischemia|DKK1 protein, human 22 DKKL1 22817830 Reprod. Biol. Endocrinol. 2012 PMC3442974 10.1186/1477-7827-10-51 5 0 2 98 Male|Mice|Humans|Animals|Spermatogenesis|Testis|Spermatocytes|Gene Expression Regulation, Developmental|RNA, Messenger|Amino Acid Sequence|Sequence Homology, Amino Acid|DKKL1 protein, human|Intercellular Signaling Peptides and Proteins 22 DLEU7 23264745 J. Cell. Sci. 2012 PMC3625813 10.1242/jcs.119701 24 7 1 16 *Retinoic Acid|*Transcriptional Activation|*Chromatin Assembly and Disassembly|retinoic acid receptor gamma|Receptors, Retinoic Acid|*Embryonic Stem Cells|CYP26A1|CDX1 protein, human|Homeodomain Proteins|histone H3 trimethyl Lys4|Histones|Gene Expression Regulation|Transcription Factors|Cell Differentiation|Promoter Regions, Genetic|Epigenesis, Genetic|Response Elements|Transcription Start Site 23 DLEU7 22939871 Gene 2012 10.1016/j.gene.2012.08.024 0 0 0 16 Animals|Humans|*Xenopus|Phylogeny|Genome-Wide Association Study|Xenopus Proteins|*Embryogenesis|Xenopus laevis|Gastrula|In Situ Hybridization|Amino Acid Sequence|Gene Expression Regulation, Developmental|Mesoderm|Sequence Homology, Amino Acid|Neural Tube|Fibroblast Growth Factor|FGF Receptor|Notochord|DNA, Complementary|DLEU7 protein, human 23 DLEU7 22720208 Oncoimmunology 2012 PMC3376971 10.4161/onci.1.1.18400 23 2 2 16 Humans|*B-Lymphocyte Subsets|*Leukemia, Lymphocytic, Chronic, B-Cell|Epstein Barr Virus|*Epstein Barr Virus Infection|Epstein-Barr Virus Nuclear Antigens|*Cell Line|Cell Transformation, Viral|*Cells, Cultured|B-Lymphocytes|Viral Proteins|Antigens, Viral|Tumor Cells, Cultured|Lymphocyte Activation|Cell Division 23 DLEU7 22591386 Curr. Pharm. Des. 2012 10.2174/138161212801227104 8 2 0 16 Humans|Mice|Animals|*Leukemia, Lymphocytic, Chronic, B-Cell|ZAP70 protein, human|ZAP-70 Protein-Tyrosine Kinase|MicroRNAs|13q deletion syndrome|Chromosome Deletion|B-Lymphocytes|Proto-Oncogene Proteins|Antigens, CD19|Transcription Factor NF-kB|Chromosomal Abnormalities|Disease Models, Animal|Chromosomes, Human, Pair 13 23 DLEU7 22424883 J. Allergy Clin. Immunol. 2012 PMC3340499 10.1016/j.jaci.2012.01.074 40 5 1 16 Humans|Adult|*Genome-Wide Association Study|*Asthma|Vital Capacity|Forced Expiratory Volume|Lung|Chronic Obstructive Pulmonary Disease|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease 23 DMRTA2 23175770 Biol. Reprod. 2012 10.1095/biolreprod.112.105130 7 0 0 12 Animals|Male|*Zebrafish|*Cyclin-Dependent Kinase Inhibitor p18|*Testis|Zebrafish Proteins|*Spermatogenesis|Transcription Factors|Homeodomain Proteins|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Telencephalon|Animals, Genetically Modified|Promoter Regions, Genetic|Fibroblast Growth Factor|Embryonic Development 25 DMRTA2 23064029 Dev. Biol. 2012 10.1016/j.ydbio.2012.10.003 11 3 0 12 Animals|Male|Female|*Xenopus laevis|*Ectoderm|*Neurogenesis|Transcription Factors|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|Xenopus Proteins|Gene Expression Regulation, Developmental|Otx2 Transcription Factor|Neural Crest|Neurons|In Situ Hybridization|Sea Anemones|Signal Transduction|DNA Primers 25 DMRTA2 23056351 PLoS ONE 2012 PMC3462758 10.1371/journal.pone.0046577 18 6 3 12 Mice|Animals|*Transcription Factor|*Cerebral Cortex|Homeodomain Proteins|*Embryonic Development|Gene Expression Regulation, Developmental|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|Neurogenesis|Hippocampus|Wnt Proteins|Neurons|*Mammals 25 DMRTA2 22552957 Mar. Biotechnol. 2012 10.1007/s10126-012-9451-6 6 0 1 12 Male|Female|Animals|*Sex Differentiation|*Scophthalmus maximus|Random Amplified Polymorphic DNA Technique|Sexual Maturation|*Markers, DNA|Quantitative Trait Loci|Genetic Linkage|Chromosome Mapping|Sex Determination Processes|Gonad|Microsatellite Repeats|Sexual Dimorphism|DNA 25 DMXL2 22707207 Proteomics 2012 10.1002/pmic.201100675 9 0 2 56 *Proteomics|Protein Interaction Mapping|Proteins|Mass Spectrometry|Protein Binding|Chromatography, Affinity|Peptides|Immunoprecipitation 27 DNAJC14 22915803 J. Virol. 2012 PMC3486285 10.1128/JVI.01022-12 15 0 2 65 *Flavivirus|Yellow fever virus|Proteins, Viral Nonstructural|Virus Replication|Molecular Chaperones|Host-Pathogen Interactions|Cell Line|DNAJB1 protein, human 20 DNAJC14 22815758 PLoS ONE 2012 PMC3398031 10.1371/journal.pone.0040522 9 16 0 65 Humans|*Receptor, CCR5|HIV Infections|CXCR4 protein, human|Receptors, CXCR4|*Molecular Chaperone|*Signal Transduction|Plasma Membrane|TYRP1 protein, human|*Membrane Glycoproteins|*Chemokines|Protein Binding|Protein Transport|Carrier Proteins|Ligands|Receptors, Dopamine|CCR5 protein, human 20 DOC2A 23246699 Gene 2012 10.1016/j.gene.2012.11.043 4 0 1 31 Humans|*Stomach Neoplasms|Case-Control Studies|*Asian Continental Ancestry Group|Haplotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Allele|Genotype|Odds Ratio|Risk Factors|*GTPase-Activating Proteins|DAB2 protein, human|Tumor Suppressor Proteins|Adaptor Proteins, Signal Transducing 42 DOC2A 22522155 Yi Chuan 2012 10.3724/sp.j.1005.2012.00389 0 1 0 31 Munc-18 Proteins|Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor|Membrane Fusion|Syntaxin|*Biological Transport|Protein Binding|Transport Vesicles|*CD59 Antigens 42 DRAM2 22935150 Reprod. Fertil. Dev. 2012 10.1071/RD11201 12 0 0 31 Female|Humans|*Follicular Fluid|*Polycystic Ovary Syndrome|Proteomics|Granulosa Cells|Two Dimensional Gel Electrophoresis|Infertility, Female|Western Blot|TYRP1 protein, human|*Membrane Glycoproteins|*Ovarian Hyperstimulation Syndrome|mRNA|APOA1 protein, human|Apolipoprotein A-I|Downregulation|Upregulation 21 DRP2 23152929 PLoS ONE 2012 PMC3496707 10.1371/journal.pone.0049722 4 12 0 48 Animals|Mice|microtubule-associated protein 1B|syntrophin|dystrophin-related protein 2|*Muscle Proteins|syntrophin alpha1|*Calcium-Binding Proteins|*Microtubule-Associated Proteins|*Membrane Proteins|Dystrophin-Associated Proteins|ezrin|Cytoskeletal Proteins|Microtubule|Protein Binding|Adaptor Proteins, Signal Transducing|Signal Transduction|*Peripheral Nervous System 49 DRP2 22764250 J. Neurosci. 2012 PMC3400949 10.1523/JNEUROSCI.1220-12.2012 27 10 5 48 Humans|Mice|Animals|periaxin|*Dystroglycans|dystrophin-related protein 2|*Schwann Cells|*Muscle Proteins|Myelin|Utrophin|Plasma Membrane|Dystrophin|Sciatic Nerve|Nerve Fibers, Myelinated|Axons|Cytoplasm 49 EIF1AY 22365286 Gend Med 2012 PMC3454519 10.1016/j.genm.2012.01.005 9 2 0 31 Humans|Female|Male|*Stroke|*Brain Ischemia|*Genes, Y-Linked|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Sex Differences|Risk Factors 26 EIF1AY 22341705 Theriogenology 2012 10.1016/j.theriogenology.2011.11.027 1 0 0 31 Male|Cattle|Animals|*Blastocysts|Embryo, Mammalian|Fertilization in Vitro|Sex Determination Analysis|*Gene Expression|Polymerase Chain Reaction|RNA, Messenger|DNA 26 ENOSF1 22219046 J. Mol. Neurosci. 2012 10.1007/s12031-011-9702-4 5 8 1 12 Animals|Humans|*STAT2 Transcription Factor|Phosphatidylinositol 3-Kinases|RECQL protein, human|RecQ Helicases|Genetic Predisposition to Disease|*Cerebrum|Regulatory Network, Gene|*Telencephalon|Cell Differentiation|Computational Biology|Cell Cycle|Cell Proliferation|Chimpanzee|Wnt Signaling Pathway|Biological Transport|PHYH protein, human|Mixed Function Oxygenases 23 ERI3 22405114 Rev Mal Respir 2012 10.1016/j.rmr.2011.07.008 0 0 0 23 Humans|*Follow-Up Studies|Quality of Life|Asbestos|*Occupational Exposure|Asbestosis|Mesothelioma|Occupational Diseases|Pleural Diseases|Lung Neoplasms|Tomography, X-Ray Computed|Screening|Incidence 25 ERI3 22292704 Dis. Esophagus 2012 10.1111/j.1442-2050.2011.01312.x 5 0 1 23 Humans|*Esophageal Cancer|Survival Rate|Socioeconomic Factors|Gastrointestinal Neoplasms|Registry|Health Services Accessibility|Residence Characteristics|Social Environment|*Rare Diseases|France 25 ERMN 23198089 Sci Rep 2012 PMC3509349 10.1038/srep00899 11 7 2 57 F-actin-binding proteins|*Microfilament Proteins|*Carrier Proteins|F-Actin|Amino Acid Sequence|Protein Binding|Protein Folding|Binding Sites|Recombinant Proteins|Sequence Homology, Amino Acid|Circular Dichroism|Models, Molecular 24 FAIM3 22763987 Rheumatology (Oxford) 2012 10.1093/rheumatology/kes151 2 0 0 72 Humans|*Synovial Fluid|*Arthritis, Juvenile|*Gene Expression Profiling|Leukocytes, Mononuclear|*Microarray Analysis|*Mononuclear Phagocyte System|Immunity, Innate 23 FAM167A 23053960 Mol. Biol. Rep. 2012 10.1007/s11033-012-1952-x 27 1 5 62 Humans|*Genome-Wide Association Study|*Lupus Erythematosus, Systemic|Single Nucleotide Polymorphisms|*Rheumatoid Arthritis|Genetic Predisposition to Disease|IRF5 protein, human|Interferon Regulatory Factors|STAT4 Transcription Factor|Linkage Disequilibrium|HLA-DR alpha-Chains|Genotype|Case-Control Studies|Signal Transduction|TPH2 protein, human|Tryptophan Hydroxylase|TNPO3 protein, human|beta Karyopherins 25 FAM167A 23049788 PLoS ONE 2012 PMC3458859 10.1371/journal.pone.0045356 9 1 0 62 Humans|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|STAT4 Transcription Factor|Genome-Wide Association Study|European Continental Ancestry Group|Case-Control Studies 25 FASTK 22626544 J. Steroid Biochem. Mol. Biol. 2012 PMC3408799 10.1016/j.jsbmb.2012.05.001 7 76 0 83 Animals|Humans|VDR protein, human|*Receptors, Calcitriol|*Calcitriol|Caco-2 Cells|HEK293 Cells|dihydroxy-vitamin D3|*Vitamin D|DRIP, VDR interacting protein complex|*Mediator Complex|*Signal Transduction|Gene Expression Regulation|Retinoid X Receptors|Transcriptional Activation|Promoter Regions, Genetic|Yeast Two-Hybrid System 24 FCRL1 22892829 Braz. J. Med. Biol. Res. 2012 PMC3854230 10.1590/s0100-879x2012007500130 5 1 0 2 Humans|*Hepatitis B virus|*Fc Receptor|*Hepatitis B Virus Infection|Hepatitis B, Chronic|*Lymphocyte Activation|CD8-Positive T-Lymphocytes|B Cells|Disease Progression|FCRL1 protein, human|Membrane Proteins 34 FERD3L 23254923 J. Mol. Neurosci. 2012 10.1007/s12031-012-9939-6 1 3 0 19 *Dopaminergic Neurons|*Gene Regulatory Networks|Hedgehog Proteins|*Mesencephalon|*Cell Differentiation|Transcription Factor|Homeodomain Proteins|Hepatocyte Nuclear Factor 3-beta|Basic Helix-Loop-Helix Transcription Factors|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Stem Cells|Signal Transduction|Dopamine 21 FERD3L 22696295 Development 2012 PMC3383233 10.1242/dev.081034 23 1 1 19 Chick Embryo|Mice|Animals|*Up-Regulation|*Mesencephalon|*Dopamine|TAL2 protein, human|Basic Helix-Loop-Helix Transcription Factors|Hepatocyte Nuclear Factor 3-alpha|LIM-Homeodomain Proteins|Hepatocyte Nuclear Factor 3-beta|Homeodomain Proteins|*Genome|Embryo, Mammalian|Cell Differentiation|Gene Expression Regulation, Developmental|*Transcriptional Activation|Dopaminergic Neurons|Nerve Tissue Proteins|Stem Cells|Hedgehog Proteins 21 FERD3L 22628249 Am. J. Med. Genet. A 2012 10.1002/ajmg.a.35367 1 0 0 19 Humans|Female|Saethre-Chotzen Syndrome|*Chromosome 3|Twist-Related Protein 1|*Chromosome Aberrations|*Phenotype|Chromosome Deletion|Karyotyping|Comparative Genomic Hybridization|*Learning Disability|Intellectual Disability|In Situ Hybridization, Fluorescence|Nuclear Proteins|Immunoglobulin E|Brazil|CACNA2D2 protein, human|Calcium Channels|DOCK3 protein, human|Nerve Tissue Proteins 21 FILIP1 23174249 J. Urol. 2012 PMC3581042 10.1016/j.juro.2012.08.188 12 1 0 40 Humans|Male|*CpG Islands|*DNA Methylation|*Prostate Cancer|Prostate|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Gene Silencing|Tumor Cells, Cultured|*Isoforms|FILIP1L protein, human|Intracellular Signaling Peptides and Proteins 22 FILIP1 23087206 Mol. Biol. Cell 2012 PMC3521688 10.1091/mbc.E12-07-0555 15 28 3 40 *Actins|*Cytoskeleton|*Microtubules|*Golgi Apparatus|rho GTPases|RHOA protein, human|rhoA GTP-Binding Protein|Arp2-3 Complex|FLNA protein, human|Filamin A|Actin Filament|Cell Migration|Cell Adhesion|Signal Transduction|Binding Protein 22 FILIP1 22900064 PLoS ONE 2012 PMC3416772 10.1371/journal.pone.0042921 5 33 0 40 Humans|Female|*Topoisomerase II|Doxorubicin|Etoposide|Topoisomerase II Inhibitors|POU2F1 protein, human|*Oct 1 Transcription Factor|Cell Line, Tumor|Ovarian Cancer|Gene Expression Regulation, Neoplastic|ICRF187|Mitoxantrone|Promoter Regions, Genetic|Carrier Proteins|FILIP1L protein, human|Intracellular Signaling Peptides and Proteins 22 FILIP1 22763110 Lancet 2012 PMC3443899 10.1016/S0140-6736(12)60681-3 113 2 12 40 *Genome-Wide Association Study|Genetic Predisposition to Disease|Osteoarthritis, Hip|Polymorphism, Single Nucleotide|Osteoarthritis, Knee|Case-Control Studies 22 FILIP1 22561202 Eur J Med Genet 2012 10.1016/j.ejmg.2012.03.003 9 0 1 40 Humans|*Intellectual Disability|Chromosome 6, monosomy 6q|Chromosome Deletion|*Chromosome 1|*Syndrome|Abnormalities, Multiple|Karyotyping|Phenotype|Genetic Association Studies|In Situ Hybridization, Fluorescence|Chromosomes, Human, Pair 6 22 FJX1 22493357 Anticancer Res. 2012 0 0 0 72 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Neoplasm Recurrence, Local|Oligonucleotide Array Sequence Analysis|Neoplasm Staging|Gene Expression Profiling|*Genomics 26 FLVCR2 22805872 J. Cereb. Blood Flow Metab. 2012 PMC3493995 10.1038/jcbfm.2012.107 5 0 1 41 Rats|Animals|*Actins|*Stroke|Brain Ischemia|Zones, Subventricular|Microglia|Infarction, Middle Cerebral Artery|Neurogenesis|Glial Fibrillary Acidic Protein|*Ischemia|Neurons|Corpus Callosum|Corpus Striatum|Pericytes|Muscle, Smooth 22 foxd4 22876580 Genet. Couns. 2012 1 0 0 58 Infant|Humans|Female|*Cerebral Palsy|Chromosome 9, partial monosomy 9p|*Chromosome Deletion|*Chromosomes, Human, Pair 9|Abnormalities, Multiple|In Situ Hybridization, Fluorescence|DOCK8 protein, human|Guanine Nucleotide Exchange Factors|Tumor Suppressor Proteins|VLDL receptor|Receptors, LDL 27 foxd4 22425621 Dev. Biol. 2012 PMC3679181 10.1016/j.ydbio.2012.03.004 11 50 0 58 Animals|*Neural Plate|*Ectoderm|Xenopus Proteins|*Nervous System|Xenopus laevis|Gene Expression Regulation, Developmental|Cell Differentiation|Transcriptional Activation|Forkhead Transcription Factors|Signal Transduction 27 FOXJ3 23047984 Am. J. Physiol. Endocrinol. Metab. 2012 10.1152/ajpendo.00097.2012 35 2 8 127 Mice|Animals|mitochondrial transcription factor A|*Organelle Biogenesis|*C57BL Mice|*Transcription Factors|*DNA-Binding Proteins|*Mitochondrial Proteins|*Muscle, Skeletal|Myogenesis|Myoblast|MicroRNAs|Cell Differentiation|Upregulation|Downregulation|3' Untranslated Region|Gene Expression Regulation|Mitochondria|Cell Proliferation|Transcriptional Activation 21 FOXJ3 22740631 Mol. Biol. Cell 2012 PMC3418304 10.1091/mbc.E11-02-0170 0 40 3 127 Humans|Chromatin Immunoprecipitation|Cell Cycle|Promoter Regions, Genetic|Binding Sites|Transcription, Genetic|Cell Cycle Gene|Forkhead Transcription Factors|Gene Expression Regulation|*Cell Cycle Control|Protein Binding|E2F1 Transcription Factor|Cell Division|DNA|FOXM1 protein, human|Forkhead Box Protein M1|FOXK1 protein, human|GSDMD protein, human|Neoplasm Proteins 21 GAGE1 23156676 Mol. Biol. (Mosk.) 2012 0 0 0 20 Humans|Male|*mRNA|*Testis|*Early Detection of Cancer|*Colorectal Cancer|Neoplastic Cells, Circulating|Carcinoembryonic Antigen|Biomarkers, Tumor|RNA, Neoplasm|Neoplasm Staging|Sensitivity and Specificity|*Colonic Neoplasms 48 GBX1 22826214 Dev. Dyn. 2012 10.1002/dvdy.23834 2 0 1 17 Animals|*Retinoic Acid|*Feathers|*Cell Transdifferentiation|*Epidermis|Epidermal Cells|Homeodomain Proteins|Skin|Homeobox Gene|Transcription Factors|Cell Differentiation|Morphogenesis|Gene Expression Regulation, Developmental|Retinol|Epithelium 34 GBX1 22252490 Int. J. Dev. Biol. 2012 10.1387/ijdb.113326ao 3 5 0 17 34 GIMAP4 23041938 Ann. Rheum. Dis. 2012 10.1136/annrheumdis-2011-200288 33 1 4 68 Humans|*Genome-Wide Association Study|*Behcet Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Gene Frequency|Genotype|Case-Control Studies 29 GLIPR2 22560898 Biochim. Biophys. Acta 2012 10.1016/j.bbamem.2012.04.016 15 5 1 52 Animals|*Lipid Bilayers|*Dimerization|Golgi Apparatus|Liposomes|Membrane Proteins|Protein Binding|Amino Acid Sequence|pathogenesis-related proteins, plant|Plant Proteins|Cytosol 21 glycolisis 22892812 Hypertension 2012 PMC4775096 10.1161/HYPERTENSIONAHA.111.190389 5 7 0 0 Female|Humans|Mice|Animals|*Receptors, Estrogen|*C57BL Mice|Estrogen Receptor beta|Oestradiol|Estrogen Receptor alpha|Estrogens|Ovariectomy|Cardiac Hypertrophy|Myocardium|Mice, Knockout|Uterus|Glucose 23 GOLGA3 22814606 Dev. Cell 2012 PMC3417773 10.1016/j.devcel.2012.05.023 37 34 7 189 Animals|*Dyneins|*Golgi Apparatus|Microtubules|Microtubule-Associated Proteins|Intracellular Membranes|Centrosome|ADP-Ribosylation Factor 1|Cell Movement|Cell Membrane 46 GOLGA3 22542470 Vaccine 2012 PMC3367131 10.1016/j.vaccine.2012.04.055 38 2 1 189 Humans|*Smallpox Vaccine|*Genome-Wide Association Study|Smallpox|Neutralizing Antibody|*Response, Antibody|Humoral Immunity|Antibodies, Viral|Haplotypes|SNPs|European Continental Ancestry Group|African Americans|Vaccination|Cytokines|GREM2 protein, human|Intercellular Signaling Peptides and Proteins|KIF6 protein, human|Kinesin 46 GPR26 22815809 PLoS ONE 2012 PMC3398048 10.1371/journal.pone.0040764 4 1 0 71 Humans|Mice|Animals|*Adiposity|*AMP-Activated Protein Kinases|Caenorhabditis elegans|*Obesity|*Hyperphagia|*Hypothalamus|Rimonabant|Body Weight|Leptin|Diet|Energy Metabolism|Mice, Knockout 20 GPR26 22383091 J. Assoc. Res. Otolaryngol. 2012 PMC3346896 10.1007/s10162-012-0316-5 1 0 0 71 Mice|Humans|Animals|Cochlea|*Insertion Mutation|Vestibule, Labyrinth|Stria Vascularis|Transgenic Mouse|Vestibular Diseases|Phenotype|Hearing Loss|Deafness|Semicircular Canals|Homozygote|Gene Expression Regulation, Developmental 20 GPR85 22968816 Neuropsychopharmacology 2012 PMC3527120 10.1038/npp.2012.184 3 0 1 29 Humans|Male|Female|*Alleles|*Healthy Volunteers|*Schizophrenia|*Functional MRI|Brain|Brain Mapping|Dorsolateral Prefrontal Cortex|Amygdala|Emotion|Facial Expression|*Phenotypes|Working Memory|Image Processing, Computer-Assisted|Genotype|Genetic Predisposition to Disease|Pattern Recognition, Visual|Polymorphism, Single Nucleotide|Hippocampal Formation 25 GPR85 22697179 Eur. J. Neurosci. 2012 PMC3466408 10.1111/j.1460-9568.2012.08180.x 9 3 1 29 Humans|Animals|Mice|*Risk Factors|*Neurogenesis|*Memory|*Hippocampus|*Schizophrenia|Neurons|Maze Learning|Brain|Mice, Knockout|Cognition|Bromodeoxyuridine 25 GRIN3B 22723691 J. Neurosci. 2012 PMC6620993 10.1523/JNEUROSCI.6301-11.2012 15 0 3 31 Mice|Animals|Transcription Factors|PAX2 Transcription Factor|Homeodomain Proteins|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|In Situ Hybridization|Spinal Cord|gamma-Aminobutyric Acid|Cell Differentiation|Gene Expression Regulation, Developmental|glutamate receptor ionotropic, AMPA 3|Receptors, AMPA|GABAergic Neurons|Embryo, Mammalian|*Peptide Receptor|Tlx3 protein, mouse|Tlx1 protein, mouse 21 GULP1 23167255 Biochem. J. 2012 PMC3612536 10.1042/BJ20121100 1 1 0 148 *Low Density Lipoprotein Receptor-Related Protein-1|*Phosphotyrosine|Amyloid beta-Protein Precursor|Alzheimer Disease|*Active Transport, Cell Nucleus|Adaptor Proteins, Signal Transducing|Nerve Tissue Proteins|Nuclear Proteins|Protein Binding|Binding Sites|*Protein Domains|Protein Transport|Transfection|Lipoproteins, LDL 37 GULP1 22829758 PLoS Comput. Biol. 2012 PMC3400575 10.1371/journal.pcbi.1002597 6 16 1 148 Humans|*Chronic Obstructive Pulmonary Disease|Lung|Cellular Senescence|Smoke|Cells, Epithelial|Oxidative Stress|Brachyury protein|*T-Box Domain Proteins|Inflammation|Smoking|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Gene Expression Regulation|Apoptosis|Cyclin-Dependent Kinase Inhibitor-2A|Cell Line|*Fetal Proteins 37 GULP1 22566688 Mol. Cell. Biol. 2012 PMC3416206 10.1128/MCB.06743-11 34 6 2 148 *Phosphatidylserines|Phagocytosis|*Integrins|*Carrier Proteins|*Erythrocytes|Adaptor Proteins, Signal Transducing|Signal Transduction|Protein Binding|phosphatidylserine receptor|Receptors, Cell Surface|Cell Adhesion Molecules, Neuronal|Apoptosis|Protein Transport|Amino Acid Sequence 37 HMG20B 22818216 J. Comp. Pathol. 2012 10.1016/j.jcpa.2012.06.004 4 0 0 74 Dogs|Animals|*Transcriptome|Nerve Tissue Proteins|Receptors, Immunologic|*Nerve Sheath Neoplasms|*Fibrosarcomas|Immunohistochemistry|Skin Neoplasms|*Genetic Marker|Dog Diseases|Biomarkers, Tumor|*Skin|*Neuroectoderms|*Cell Differentiation 22 HMG20B 22570500 Proc. Natl. Acad. Sci. U.S.A. 2012 PMC3361438 10.1073/pnas.1121522109 23 8 2 74 22 HMGN3 22355284 Front Cell Neurosci 2012 PMC3280452 10.3389/fnbeh.2011.00028 22 0 5 72 Humans|Animals|Mice|*Genes, Homeobox|LMO1 protein, human|Transcription Factor|Homeodomain Proteins|*Cell Differentiation|*Cell Movement|Intellectual Disabilities|Interneurons|Epilepsy|Chromatin Immunoprecipitation|Lissencephaly|Phenotypes|*Neurogenesis|Mutations|GABAergic Neurons|Neural Stem Cells|Brain|Gene Expression Regulation 28 HTATSF1 23153325 Virol. J. 2012 PMC3511259 10.1186/1743-422X-9-272 4 8 1 139 *RNA Interference|*CD4-Positive T-Lymphocytes|*HIV-1|HIV Long Terminal Repeat|tat Gene Products, Human Immunodeficiency Virus|Virus Replication|Cell Lines|Transcriptional Activation|*HIV Seropositivity 26 IGSF11 22916035 PLoS Genet. 2012 PMC3420941 10.1371/journal.pgen.1002899 27 1 5 18 Animals|*Zebrafish|*Melanophore|Zebrafish Proteins|Embryo, Nonmammalian|Body Patterning|Neural Crest|Phenotype|Morphogenesis|Gene Expression Regulation, Developmental|Skin Pigmentation|Cell Differentiation|Alleles|*Cell Adhesion Molecules|Larvae|Interactions, Cell|Mutation 27 INSL4 22961112 J. Mol. Evol. 2012 10.1007/s00239-012-9517-0 3 0 1 17 Female|Pregnancy|Animals|*Relaxin|*Pseudogenes|Phylogeny|Sequence Alignment|Evolution, Molecular|Gene Duplication|Synteny|Mammals|Multigene Family|Primates|Genome|Amino Acid Sequence|INSL4 protein, human|Intercellular Signaling Peptides and Proteins|Insulin 45 INSL4 22573555 J. Cell. Biochem. 2012 10.1002/jcb.24110 13 0 0 17 Humans|Female|Pregnancy|syncytin|*Endogenous Retroviruses|*Cell Fusion|*Peroxisome Proliferator-Activated Receptors|*Gene Products, env|*Pregnancy Proteins|Cytotrophoblast|Placentation|Pre-Eclampsia|Placenta|Intrauterine Growth Restriction|*Cell Communication|HELLP Syndrome|*Gene Expression Regulation|*Nuclear Hormone Receptors|Genes, env|*Signal Transduction|Promoter Regions, Genetic 45 INSL4 22405815 Mol. Phylogenet. Evol. 2012 10.1016/j.ympev.2012.02.011 3 0 0 17 Humans|Animals|*Relaxin|*Insulin|Phylogeny|*Primates|*Insulin, Regular, Human|Gene Duplications|Evolution, Molecular|Genome|Mammals|Sequence Alignment|Multigene Family|Comparative Genomics 45 insl6 22961112 J. Mol. Evol. 2012 10.1007/s00239-012-9517-0 3 0 1 28 Female|Pregnancy|Animals|*Relaxin|*Pseudogenes|Phylogeny|Sequence Alignment|Evolution, Molecular|Gene Duplication|Synteny|Mammals|Multigene Family|Primates|Genome|Amino Acid Sequence|INSL4 protein, human|Intercellular Signaling Peptides and Proteins|Insulin 40 insl6 22654853 Front Endocrinol (Lausanne) 2012 PMC3356098 10.3389/fendo.2012.00011 5 23 0 28 Humans|Male|Female|Relaxin|Receptors, Peptide|Amino Acid Sequence|Protein Binding|Binding Sites|Receptors, G-Protein-Coupled|Models, Molecular|Amino Acids|Insulin|Protein Domains|HEK293 Cells|Alanine 40 insl6 22600741 Nucleic Acids Res. 2012 PMC3424568 10.1093/nar/gks429 12 6 4 28 Humans|*CpG Island|*DNA Methylation|*Promoter Regions, Genetic|*Repetitive Sequences, Nucleic Acid|Chromatin|Gene Silencing|PDLIM4 protein, human|DNA-Binding Proteins|Transcription, Genetic|DNA|Cell Line, Tumor|Transcription Factor|LIM Domain Proteins 40 insl6 22405815 Mol. Phylogenet. Evol. 2012 10.1016/j.ympev.2012.02.011 3 0 0 28 Humans|Animals|*Relaxin|*Insulin|Phylogeny|*Primates|*Insulin, Regular, Human|Gene Duplications|Evolution, Molecular|Genome|Mammals|Sequence Alignment|Multigene Family|Comparative Genomics 40 INSRR 23234507 Zebrafish 2012 PMC3760054 10.1089/zeb.2012.0781 0 0 2 284 Humans|Animals|*Zebrafish|*Tyrosine Kinase|Embryo, Nonmammalian|Embryonic Development|Signal Transduction|Genome 86 IRGC 23079848 Genet. Mol. Res. 2012 10.4238/2012.September.26.10 0 0 0 17 *Oryza|Quantitative Trait Loci|*Edible Grain|Crosses, Genetic|Chromosome Mapping|Chromosomes, Plant|*Breeding|Phenotype|Microsatellite Repeats|Amylose|Genotypes|*Plant Structures|Malaysia 32 ISM1 22736328 Hum. Reprod. 2012 10.1093/humrep/des223 23 0 3 121 Humans|Male|Mice|Animals|Embryo Culture Techniques|Embryo Transfer|Blastocyst|Fertilization in Vitro|Embryo Implantation|Embryonic Development|Oocytes|Culture Media|*Embryo, Mammalian|Spermatozoa|*Probability 26 ISM1 22714820 NMR Biomed 2012 10.1002/nbm.2814 4 0 0 121 Pregnancy|Female|Humans|*Implantation, Embryo|*Preimplantation Embryo|Embryo Transfer|*NMR Spectroscopy|Embryo Culture Techniques|Fertilization in Vitro|Pregnancy Rate|Embryo, Mammalian|Culture Media|*Magnetic Resonance Imaging|*Reproduction|*Biomarkers|Assisted Reproductive Techniques|Pyruvate 26 ITM2C 23013511 Biochem. J. 2012 10.1042/BJ20120919 2 0 0 80 *Amyloid|*Amyloidosis|*Amyloidogenic Proteins|Protein Folding|Protein Conformation|Molecular Chaperones|Models, Molecular|*Autoregulation 27 LACRT 22956620 Invest. Ophthalmol. Vis. Sci. 2012 PMC4113189 10.1167/iovs.12-10750 15 0 3 69 Humans|*Lacrimal Apparatus|Tears|*Gene Expression 27 LACRT 22918641 Invest. Ophthalmol. Vis. Sci. 2012 PMC3460390 10.1167/iovs.11-8729 11 2 0 69 Humans|Proteomics|*Tear|Dry Eye Syndrome|Lacrimal Apparatus|Eye Proteins|Glycoproteins|*Lacerations 27 laptm5 22949502 Mol. Cell. Biol. 2012 PMC3486144 10.1128/MCB.00531-12 3 2 1 113 Receptor, Pre-B Cell|LAPTM5 protein, human|*Membrane Proteins|Receptors, Antigen, B-Cell|*Lymphocyte Activation|B Cells|Pre-B-Cells|Signal Transduction|Cell Membrane|Lysosomes|Endoplasmic Reticulum 49 LHX5 23213388 Biol Open 2012 PMC3507191 10.1242/bio.20121396 1 34 0 58 Animals|*Chickens|LIM-Homeodomain Proteins|Prosencephalon|Homeodomain Proteins|Gene Expression Regulation, Developmental|Homeobox Gene|Retina|*Organogenesis|Morphogenesis|Transcription Factors|Nerve Tissue Proteins|Retinal Pigments|RNA Interference 61 LHX5 22606267 PLoS ONE 2012 PMC3351449 10.1371/journal.pone.0036516 5 7 1 58 Animals|*Zebrafish|Zebrafish Proteins|*Neurons|*Prosencephalon|DCC Receptor|Axons|Animals, Transgenic|Telencephalon|LIM-Homeodomain Proteins|Neurogenesis|Netrin-1|Nerve Growth Factors|Gene Expression Regulation, Developmental|Tumor Suppressor Proteins|Receptors, Cell Surface|Morpholinos|Transcription Factors 61 LRWD1 23152447 Genes Dev. 2012 PMC3521623 10.1101/gad.195636.112 47 2 2 85 Mice|Animals|KMT5A protein, human|*Histone-Lysine N-Methyltransferase|Methylation|Histones|Cell Cycle|Protein Processing, Post-Translational|Replication Origin|Lysine|DNA Damage|Chromosome Structures 22 LRWD1 22935713 Cell Cycle 2012 PMC3478309 10.4161/cc.21870 11 4 0 85 ORC2 protein, human|*Origin Recognition Complex|*Ubiquitin|Proteasome|Ubiquitination|Chromatin|Cell Cycle|Cell Nucleus|DNA Replication|Phosphorylation|Protein Binding|E3 Ubiquitin Ligase|Amino Acid Sequence|Adaptor Proteins, Signal Transducing|Sequestosome-1 Protein|S Phase|Cytoplasm 22 LRWD1 22810296 Epigenetics 2012 PMC3427277 10.4161/epi.21140 23 3 2 85 Histone H3|Methylations|Chromatin|*Gene Expression Regulation|Histone-Lysine N-Methyltransferase|Nucleosomes|Protein-Arginine N-Methyltransferases|Histone Code|Lysine|Binding Sites|Acetylation|Transcription Factors|Arginine|Post-Translational Modifications|Promoter Regions, Genetic 22 LRWD1 22645314 Mol. Cell. Biol. 2012 PMC3434513 10.1128/MCB.00362-12 25 3 0 85 Humans|ORC2 protein, human|Origin Recognition Complex|*DNA Replication|GMNN protein, human|Geminin|S Phase|*Cell Nucleus|Chromatin|Cell Cycle|G1 Phase|LRWD1 protein, human|Microtubule Proteins 22 LRWD1 22427655 J. Biol. Chem. 2012 PMC3340258 10.1074/jbc.M111.337980 15 1 0 85 Mice|Animals|*Heterochromatin|*Histones|*Lysine|*Leucine|*WD40 Repeats|Chromosomal Proteins, Non-Histone|Histone-Lysine N-Methyltransferase|Methylation|ORC2 protein, human|Origin Recognition Complex|Gene Silencing|Repressor Proteins|Protein Binding 22 MAP9 22672907 Cell Cycle 2012 10.4161/cc.20858 5 4 0 342 *Tumor Suppressor Protein p53|*DNA Damage|Proto-Oncogene Proteins c-mdm2|EP300 protein, human|E1A-Associated p300 Protein|Acetylation|DNA Repair|Ubiquitination|Apoptosis|Protein Binding|Cell Cycle Arrest|Cell Line, Tumor|RNA, Small Interfering 26 MAP9 22388736 Nat. Struct. Mol. Biol. 2012 10.1038/nsmb.2242 27 4 3 342 Humans|RNA Splicing|Ribonucleoproteins|Nuclear Proteins|RNA-Binding Proteins|Carrier Proteins|mRNA|Ubiquitin|Cell Nucleus|HeLa Cells 26 METRN 22344266 J. Cell. Sci. 2012 10.1242/jcs.097709 12 1 2 47 Rats|Animals|*Neurites|NGF protein, human|Nerve Growth Factor|*Cell Differentiation|PC12 Cells|PACAP|Signal Transduction|Phosphorylation|*Neurogenesis|*Cell Cycle|Gene Expression|*Cell Proliferation|Forskolin 22 MICAL2 22724020 PLoS ONE 2012 PMC3378553 10.1371/journal.pone.0039469 46 8 5 153 *Urinary Bladder Neoplasms|FGFR3 protein, human|Receptor, Fibroblast Growth Factor, Type 3|Urothelium|Mutation|Carcinoma in Situ|Cell Transformation, Neoplastic|Phenotype|Disease Progression 22 MICAL2 22331357 J. Cell. Sci. 2012 PMC3367829 10.1242/jcs.089367 31 0 4 153 Animals|Humans|Drosophila melanogaster|MICAL1 protein, human|*LIM Domain Proteins|*Cytoskeletal Proteins|*Adaptor Proteins, Signal Transducing|*Microfilaments, Actin|plexin|Nerve Tissue Proteins|Actin|Semaphorin|MICAL protein, Drosophila|DNA-Binding Proteins|Cell Adhesion Molecules|Signal Transduction|Growth Cone|Axons|Protein Binding|MICAL3 protein, human 22 MIPEP 23047795 Cancer Nurs 2012 PMC4665987 10.1097/NCC.0b013e318263f514 26 1 1 43 Humans|Male|Quality of Life|*Fatigue|*Prostatic Neoplasms|*Mitochondria|*Chronic Disease|*Gene Expression 29 MIPEP 22875794 Med Sci Law 2012 10.1258/msl.2012.011126 1 1 0 43 Humans|*DNA Fingerprinting|Nucleic Acid Amplification Techniques|DNA|Microsatellite Repeats|Genome, Human|*DNA Replication|Alleles 29 MPZL2 22489104 Acta Histochem Cytochem 2012 PMC3317495 10.1267/ahc.11057 5 1 0 144 Humans|Male|Mice|Animals|*Myelin P0 Protein|*Up-Regulation|Cadm1 protein, mouse|CADM1 protein, human|*Cell Adhesion Molecule-1|*Spermatogenesis|Sertoli Cells|Testis|Spermatids|Spermatocytes|Immunoglobulin|Cell Adhesion Molecules|Infertility, Male|*Transcriptional Activation|Cell Adhesion|Gene Expression|Membrane Proteins|In Situ Hybridization 22 MTX3 23173263 Zhongguo Zhong Xi Yi Jie He Za Zhi 2012 0 1 0 133 Humans|*Synoviocytes|*Methotrexate|sinomenine|*Rheumatoid Arthritis|*Morphinans|*Fibroblast|Synovial Membrane|TNFSF11 protein, human|Differentiation Factor, Osteoclast|Cells, Cultured|Cell Proliferation|Apoptosis|Signal Transduction 21 myo1f 22938506 Orphanet J Rare Dis 2012 PMC3495859 10.1186/1750-1172-7-60 28 4 2 128 Humans|*Hearing Loss|*Deafness|*Massively Parallel Sequencing|DNA Mutational Analysis|Hearing Loss, Sensorineural|Pedigree|Mutation|Genetic Linkage|Asian Continental Ancestry Group 25 MYO5C 22409602 Genet Test Mol Biomarkers 2012 10.1089/gtmb.2011.0092 1 1 0 604 Humans|*Diabetic Retinopathy|*Haplotypes|Gene Frequency|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Genotype|Diabetes Mellitus, Type 2|*Chromosome 22|Case-Control Studies 22 NDFIP2 22310887 Biometals 2012 PMC3493171 10.1007/s10534-012-9522-1 14 13 2 108 Animals|Humans|HEK293 Cells|*Protein Isoforms|parkin protein|Ubiquitin-Protein Ligases|Cation Transport Proteins|*Cations, Divalent|Iron|Ubiquitination|Ion Transport|mRNA|Neurons|Doxycycline|Endosomes|NDFIP1 protein, human|Carrier Proteins|Membrane Proteins 24 NEUROD4 22816789 Neuropathology 2012 10.1111/j.1440-1789.2012.01338.x 5 0 1 53 Humans|*Neurocytoma|Hedgehog Proteins|Pineocytomas|*Disease Progression|Brain Neoplasms|Cerebral Ventricle Neoplasms|Biomarkers, Tumor|Neoplasm Recurrence, Local|Genome, Human|Genes, cdc|Microarray Analysis|Pineal Gland|UBE2C protein, human|Ubiquitin-Conjugating Enzymes|INSM1 protein, human|Repressor Proteins|CHRDL2 protein, human|Extracellular Matrix Proteins 59 NEUROD4 22696677 Mol. Biol. Cell 2012 PMC3408414 10.1091/mbc.E12-04-0270 18 12 0 53 Mice|Animals|*RNA, Micro|*Oligodendrocyte Precursor Cells|Oligodendrocytes|*Neural Stem Cells|Cell Differentiation|Cell Lineage|Myelin Sheath|Gene Expression Regulation, Developmental|Neurons|Cells, Cultured|Neurogenesis|Cell Proliferation 59 NHLH1 22816789 Neuropathology 2012 10.1111/j.1440-1789.2012.01338.x 5 0 1 132 Humans|*Neurocytoma|Hedgehog Proteins|Pineocytomas|*Disease Progression|Brain Neoplasms|Cerebral Ventricle Neoplasms|Biomarkers, Tumor|Neoplasm Recurrence, Local|Genome, Human|Genes, cdc|Microarray Analysis|Pineal Gland|UBE2C protein, human|Ubiquitin-Conjugating Enzymes|INSM1 protein, human|Repressor Proteins|CHRDL2 protein, human|Extracellular Matrix Proteins 43 NHLH1 22410795 Cell Res. 2012 PMC3317568 10.1038/cr.2012.36 64 2 8 132 Animals|*Methylation|*RNA Stability|RNA, Small Interfering|RNA Silencing|MicroRNAs|Arabidopsis|Methyltransferases|RNA-Binding Proteins 43 NHLH1 22310718 Biochem. Biophys. Res. Commun. 2012 10.1016/j.bbrc.2012.01.100 4 2 0 132 Animals|Mice|NeuroD protein|*Basic Helix-Loop-Helix Transcription Factors|*Nerve Tissue Proteins|Transcription Factor|Cell Differentiation|Neuropeptides|Neurogenesis|Neurons|Gene Expression Regulation, Developmental|Northern Blotting|In Situ Hybridization|Neurod1 protein, mouse 43 OLFML3 23002094 Mol. Cancer Ther. 2012 10.1158/1535-7163.MCT-12-0245 15 2 4 48 Mice|Animals|*Pericytes|olfactomedin|Endothelial Cells|*Neovascularization, Pathologic|Drugs, Anti-Angiogenic|*Glycoproteins|*Extracellular Matrix Proteins|Carcinoma, Lewis Lung|Vascular Endothelial Growth Factor A|Cell Migration|Signal Transduction|Cell Proliferation|Anticancer Agents|Mice, Inbred C57BL|Tumor Microenvironment 21 OLFML3 22419891 Int. J. Biol. Sci. 2012 PMC3303172 10.7150/ijbs.3821 12 10 2 48 Swine|Animals|*Muscle Development|mRNA|Gene Expression Profiling|Sus scrofa|MicroRNAs|Muscle, Skeletal|Gene Expression Regulation, Developmental 21 oxsr1 23034389 Am. J. Physiol., Cell Physiol. 2012 PMC3530771 10.1152/ajpcell.00284.2012 16 0 0 594 Animals|*Proline|*Alanine|Phosphorylation|Solute Carrier Family 12, Member 2|Protein-Serine-Threonine Kinases|*Oxidative Stress|Xenopus laevis|Protein Binding|Two-Hybrid System Techniques|Oocytes|Mutation|Ion Transport|Calcium-Binding Proteins 38 oxsr1 22989884 J. Biol. Chem. 2012 PMC3488059 10.1074/jbc.M112.398750 11 6 0 594 Humans|*Lysine|WNK Lysine-Deficient Protein Kinase 1|Phosphorylation|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|Protein Kinases|Solute Carrier Family 12, Member 2|Transcription Factors|Co-Transporters|Minor Histocompatibility Antigens|Signal Transduction|*Oxidative Stress|Hypertension|Amino Acid Sequence|HeLa Cells|*Ion Transport 38 oxsr1 22886929 J Appl Toxicol 2012 10.1002/jat.2800 2 0 0 594 *Networks, Gene|Irritants|Oligonucleotide Array Sequence Analysis|Toxicogenomics|Gene Expression Profiling|Skin|Allergens|Biomarkers|Cell Line|Genes, Regulator 38 oxsr1 22668778 Neurobiol. Dis. 2012 10.1016/j.nbd.2012.05.020 20 1 1 594 Animals|Mice|*Drosophila|*Curcumin|Hydrogen Peroxide|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|*Mutations|Drosophila Proteins|Animals, Genetically Modified|Protein-Serine-Threonine Kinases|*Oxidative Stress|Dopaminergic Neurons|Parkinson Disease|Neurodegenerative Disorder|Cultured Cells|Phenotypes|Transfection|Green Fluorescent Proteins|Dopamine 38 oxsr1 22321743 Zhonghua Yi Xue Za Zhi 2012 1 0 0 594 Humans|*Adenosine Triphosphate|*Epilepsy|*Brain|*RNA, Messenger|*Gene Expression|Drug Resistant Epilepsy 38 PAGE4 22885105 Am. J. Pathol. 2012 10.1016/j.ajpath.2012.06.040 11 7 1 57 Humans|Male|*Prostate|*Prostate Cancer|Androgen Antagonists|AR protein, human|Androgen Receptor|Tosyl Compounds|Prostate-Specific Antigen|*Signal Transduction|Anilides|Androgens|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Proliferation|Nitriles|Gene Expression Regulation, Neoplastic|Protein Transport|PAGE4 protein, human|Antigens, Neoplasm 31 PALMD 22855693 PLoS ONE 2012 PMC3405040 10.1371/journal.pone.0041850 5 1 0 58 Animals|*Vertebrate|PALM protein, human|*Phosphoproteins|Palmd protein, mouse|*Membrane Proteins|*Gene, Duplicate|Genome|Multigene Family|Amino Acid Sequence|Isoforms|Evolution, Molecular|Conserved Sequence|Plasma Membrane|Sea Lamprey|Sequence Homology, Amino Acid|Phylogeny 20 PARM1 22766399 Gene 2012 10.1016/j.gene.2012.06.082 1 0 1 49 Male|Humans|Mice|Animals|*Epispadias|*Prostate|*Genes, vif|Bladder Exstrophy|*DNA Mutational Analysis|*Androgens|MUCL1 protein, human|*Mucins|Urinary Bladder|Transcription Factors|In Situ Hybridization|Sequence Analysis, DNA|Mutation 20 PARP12 22759920 Physiol. Genomics 2012 10.1152/physiolgenomics.00067.2012 17 7 1 93 Humans|Cattle|Animals|Female|Pregnancy|trophoblastin|*Pregnancy Proteins|*Interferon Type I|*Endometrium|Pregnancy, Animal|Progesterone|Oligonucleotide Array Sequence Analysis|Artificial Insemination|Gene Expression|Gene Expression Profiling|Genes, Regulator|Postpartum|RNA, Messenger|SRGAP2 protein, human|GTPase-Activating Proteins|LIMS2 protein, human|Membrane Proteins|Adaptor Proteins, Signal Transducing 20 PARP12 22623789 J. Virol. 2012 PMC3421642 10.1128/JVI.00733-12 50 0 4 93 Humans|Horses|Animals|*Alpha Virus|*Poly(ADP-ribose) Polymerase Inhibitors|Venezuelan equine encephalitis virus|Encephalomyelitis, Venezuelan Equine|Virus Replication|Cytopathogenic Effect, Viral|Type I Interferon|Virus Infection, Alpha|Antiviral Agents|Cell Line 20 PCDH11Y 22744706 Cereb. Cortex 2012 PMC3698369 10.1093/cercor/bhs181 9 1 1 45 Animals|Male|Female|Pregnancy|Humans|*Brain|Cadherins|*Fetus|Brainstem|*Prenatal Care|*Survey 24 PDE3B signalling 22967108 J. Neuroendocrinol. 2012 PMC3549038 10.1111/j.1365-2826.2012.02386.x 5 50 1 0 Male|Animals|Rats|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Leptin|*Phosphatidylinositol 3-Kinase|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|*Hypothalamus|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|Signal Transduction|Insulin|Cyclic AMP|Phosphorylation|Body Weight|Obesity|Wortmannin|Weight Loss|Neurons|Anorexia 21 pdia2 23167757 FEBS J. 2012 10.1111/febs.12063 7 0 0 61 Humans|*Protein Disulfide-Isomerases|*Glycosylation|HeLa Cells|*Dimerization|Endoplasmic Reticulum|Amino Acid Sequence|Disulfides|Histocompatibility Antigens Class I|Substrate Specificity|Antigen Presentation|Post-Translational Modifications|Mutagenesis, Site-Directed 23 pdia2 22219046 J. Mol. Neurosci. 2012 10.1007/s12031-011-9702-4 5 8 1 61 Animals|Humans|*STAT2 Transcription Factor|Phosphatidylinositol 3-Kinases|RECQL protein, human|RecQ Helicases|Genetic Predisposition to Disease|*Cerebrum|Regulatory Network, Gene|*Telencephalon|Cell Differentiation|Computational Biology|Cell Cycle|Cell Proliferation|Chimpanzee|Wnt Signaling Pathway|Biological Transport|PHYH protein, human|Mixed Function Oxygenases 23 PDZRN3 22664479 Pharmacogenomics J. 2012 10.1038/tpj.2012.24 11 0 3 80 Humans|*Carcinoma, Non-Small-Cell Lung|*Irinotecan|*Genome-Wide Association Study|*Lung Neoplasms|Camptothecin|Antineoplastic Agents, Phytogenic|Neutropenia|Antineoplastic Combined Chemotherapy Protocols|Single Nucleotide Polymorphisms|Treatment Outcome 26 PDZRN3 22609016 Biochimie 2012 10.1016/j.biochi.2012.05.002 3 4 1 80 Rats|Animals|PC12 Cells|NGF protein, human|Nerve Growth Factor|Receptors, Neurotrophin|Membrane Proteins|Nerve Tissue Proteins|Phosphoproteins|Neurons|Neurogenesis|Amino Acid Sequence|*Biophysical Phenomena 26 PDZRN3 22290856 J. Child Neurol. 2012 10.1177/0883073811431016 6 0 0 80 Child|Humans|Chromosome 3, monosomy 3p|*Chromosome Deletion|*Chromosomes, Human, Pair 3|Intellectual Disability|Abnormalities, Multiple|Developmental Disabilities|Karyotyping|Syndrome|Genetic Association Studies|*Chromosome Aberrations|Face 26 PDZRN3 22252497 Int. J. Dev. Biol. 2012 PMC3418813 10.1387/ijdb.113437ld 1 0 0 80 Animals|*Zebrafish|Zebrafish Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|In Situ Hybridization|Amino Acid Sequence|Retina|Cloning, Molecular|Central Nervous System|Sequence Homology, Amino Acid|Embryonic Development|DNA, Complementary 26 PGDF 23056168 PLoS ONE 2012 PMC3466257 10.1371/journal.pone.0041472 2 29 0 0 *Fibrin|*Platelet Derived Growth Factor B|CD44 protein, human|Hyaluronan Receptors|*Colonic Neoplasms|P-Selectin|Cell Adhesion|Cell Line, Tumor|Ligands|Protein Binding|fibrin receptor|Receptors, Peptide|Protein Isoforms|Glycosaminoglycans|Colon 49 PGDF 22302306 Mol. Cell. Biochem. 2012 10.1007/s11010-012-1249-3 11 14 0 0 *Focal Adhesion Kinase|*Focal Adhesions|*Phosphorylation|*Platelet-Derived Growth Factor|*Tyrosine|PTK2 protein, human|*Focal Adhesion Kinase 1|GIT1 protein, human|*Adaptor Proteins, Signal Transducing|*Cell Cycle Proteins|*Osteoblasts|Cell Migration|src-Family Kinases|Signal Transduction|Mitogen-Activated Protein Kinase 3|GTPase-Activating Proteins|siRNA 49 PHPT1 23185754 Zhongguo Zhong Xi Yi Jie He Za Zhi 2012 4 0 0 62 Humans|*Gastritis, Atrophic|*Syndrome|Gastritis|Medicine, Chinese Traditional|Oligonucleotide Array Sequence Analysis|*Energy Metabolism|Gastric Mucosa|*Mucositis|Gene Expression|*Precancerous Conditions|*Musculoskeletal Diseases|Case-Control Studies 42 PILRA 23142774 Nat. Immunol. 2012 10.1038/ni.2456 21 1 0 23 Mice|Animals|*Neutrophil Infiltration|*Inflammation|N-Formylmethionine Leucyl-Phenylalanine|*Receptors, Fc|Neutrophils|Cell Adhesion|Integrins|Signal Transduction|Cell Movement|Macrophages|ICAM1 protein, human|Intercellular Adhesion Molecule-1 38 PILRA 22695228 Virol. J. 2012 PMC3402990 10.1186/1743-422X-9-112 10 17 0 23 Humans|*Herpesvirus 1, Human|glycoprotein B, Simplexvirus|*Viral Envelope Proteins|Virus Internalization|Membrane Fusion|Virions|Cell Line|Glycoproteins|Amino Acids|Immunoglobulins 38 Pl15 22832717 Dis. Aquat. Org. 2012 10.3354/dao02466 0 0 0 0 Animals|*White spot syndrome virus 1|*Penaeidae|*Sargassum|*Sodium Alginate|Nested PCR 23 PLAC4 22924494 Genet Test Mol Biomarkers 2012 PMC3438833 10.1089/gtmb.2012.0053 0 0 0 0 Humans|Female|Pregnancy|*Down Syndrome|*RNA|*Noninvasive Prenatal Testing|*Alleles|Prenatal Diagnosis|*Placenta|*Chinese|Gene Frequency|Polymorphism, Single Nucleotide|RNA, Messenger|*Plasma|Case-Control Studies 22 PRDM8 22961547 Brain 2012 PMC3437029 10.1093/brain/aws205 15 1 2 41 Humans|Adolescent|*Lafora Disease|Protein Tyrosine Phosphatases, Non-Receptor|*Progressive Myoclonus Epilepsies|Dual-Specificity Phosphatases|Glycogen|Inclusion Bodies|Carrier Proteins|Ubiquitin|Ubiquitin-Protein Ligases|Mutation|EPM2A protein, human 25 RAPGEF6 23219993 Gene 2012 10.1016/j.gene.2012.11.026 7 0 1 96 Humans|*Nuclear Respiratory Factor 1|Transcription Factor|*Neurite Outgrowth|Nuclear Respiratory Factors|DNA-Binding Proteins|Gene Expression Regulation|Electrophoretic Mobility Shift Assay|NF-E2-Related Factor 1|Chromatin Immunoprecipitation|Trans-Activators|Response Element|Promoter Regions, Genetic|Base Sequence|Binding Sites|Neuroblastoma|mRNA|Cell Line, Tumor|Protein Binding 25 RASGEF1B 22903878 Am. J. Med. Genet. A 2012 10.1002/ajmg.a.35568 0 0 0 25 Child|Humans|Chromosome 4q- Syndrome|*Chromosome Deletion|*Chromosome Disorders|Intellectual Disability|Abnormalities, Multiple|Comparative Genomic Hybridization|Hypotonia|Developmental Disabilities|*Chromosomes, Human, Pair 4|Phenotype|Syndrome|In Situ Hybridization, Fluorescence 28 RASGEF1B 22355284 Front Cell Neurosci 2012 PMC3280452 10.3389/fnbeh.2011.00028 22 0 5 25 Humans|Animals|Mice|*Genes, Homeobox|LMO1 protein, human|Transcription Factor|Homeodomain Proteins|*Cell Differentiation|*Cell Movement|Intellectual Disabilities|Interneurons|Epilepsy|Chromatin Immunoprecipitation|Lissencephaly|Phenotypes|*Neurogenesis|Mutations|GABAergic Neurons|Neural Stem Cells|Brain|Gene Expression Regulation 28 Resp18 22561140 Regul. Pept. 2012 10.1016/j.regpep.2012.04.008 2 0 0 423 Rats|Animals|regulated endocrine secretory protein 18|*Gastrin Cells|*Nerve Tissue Proteins|Gastrin|Pyloric Antrum|Gland, Pituitary|mRNA|Gastric Mucosa|Ghrelin|Immunohistochemistry|Pantoprazole|Neurons 23 RIMS2 22753485 Proc. Natl. Acad. Sci. U.S.A. 2012 PMC3406861 10.1073/pnas.1209318109 38 1 2 81 Mice|Animals|Humans|HEK293 Cells|Synaptic Vesicles|Presynaptic Terminals|rab3 GTP-Binding Proteins|Calcium Channels|RBBP8 protein, human|Synapses|*Nuclear Proteins|Synaptic Transmission|Calcium|GTP-Binding Proteins|Mice, Knockout|Isoforms|Neurons 35 RTTN 22939636 Am. J. Hum. Genet. 2012 PMC3511998 10.1016/j.ajhg.2012.07.008 18 1 3 72 Animals|Humans|Mice|*Cilia|Drosophila melanogaster|*Cerebral Cortex|*Mutations|Polymicrogyria|Microcephaly|Centrioles|Carrier Proteins|Cell Cycle Proteins|Brain|Neurons|rotatin protein, human 21 SAMSN1 23087808 Hematol Rep 2012 PMC3475941 10.4081/hr.2012.e19 6 16 0 51 Humans|*Multiple Myeloma|In Situ Hybridization, Fluorescence|Comparative Genomic Hybridization|DNA Copy Number Variations|*Ethnic Groups|*Translocation, Genetic|Chromosomal Aberration|*Genomics|Bone Marrow|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport|FBXL5 protein, human|Ubiquitin-Protein Ligase Complexes|F-Box Proteins|ATP8B4 protein, human|Adenosine Triphosphatases 25 SBSN 23144906 PLoS ONE 2012 PMC3492451 10.1371/journal.pone.0048582 15 2 2 57 *Carcinoma, Adenoid Cystic|Salivary Gland Neoplasms|*DNA Methylation|Salivary Glands|Promoter Regions, Genetic|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 23 SBSN 23073817 Knee Surg Sports Traumatol Arthrosc 2012 10.1007/s00167-012-2243-8 6 0 0 57 *Prospective Studies|Anterior Cruciate Ligament Reconstruction|*Hamstring Muscles|Hamstring Tendons|Anterior Cruciate Ligament Injuries|Peripheral Nerve Injuries|Tissue and Organ Harvesting|*Trauma, Nervous System 23 SBSN 22792300 PLoS ONE 2012 PMC3390376 10.1371/journal.pone.0040389 12 26 2 57 Humans|Male|Epigenesis, Genetic|*Oncogene|CpG Island|DNA Methylation|Promoter Regions, Genetic|DNA-Binding Proteins|Transcription Start Site|Gene Expression Regulation, Neoplastic|Antigens, Neoplasm|Cell Line, Tumor|Lung Cancer|SBSN protein, human|Antigens, Differentiation|Neoplasm Proteins 23 SCAMP2 23000966 Nat. Cell Biol. 2012 PMC4495918 10.1038/ncb2577 0 7 3 316 Humans|*Cytokinesis|*ESCRT III|*Endosome|rab GTP-Binding Proteins|Actin|I-kappa B Kinase|Telophase|Mitosis|HeLa Cells|*Embryonic Development 26 SCAMP2 22628180 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2012 PMC3795298 10.1002/ajmg.b.32072 0 0 2 316 *Genome-Wide Association Study|Multifactorial Inheritance|Neuroticism|Extroversion|SNPs|Personality|Genetic Predisposition to Disease|Phenotype|Anxiety Disorders|Anxiety|Genotype|Personality Disorders|Genetic Variation|Depressive Disorder, Major|Cohort Studies 26 SCAMP2 22211456 Biol. Cell 2012 10.1111/boc.201100049 7 0 1 316 Humans|Pregnancy|Female|Animals|Henle Loop|Solute Carrier Family 12, Member 1|Bartters Syndrome|*Sodium|Sodium-Potassium-Chloride Symporters|Sodium Chloride, Dietary|Hypertension|Kidney|*Protein Transport|Blood Pressure|Diuretics, Loop|Phosphorylation|Sodium Chloride|Diabetes Mellitus, Type 2 26 SCRN1 23211594 Biochem. Biophys. Res. Commun. 2012 10.1016/j.bbrc.2012.11.093 8 1 2 65 Humans|Mice|Animals|Infant|*Transgenic Mouse|*Alzheimer Disease|*Proteomics|Neurodegenerative Diseases|tau Proteins|Neurofibrillary Tangles|*Disease Models, Animal|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|*Cerebral Cortex|Senile Plaques|Proteome|Brain|Western Blotting|SCRN1 protein, human|Nerve Tissue Proteins 21 SEZ6L 22972171 Int. J. Hematol. 2012 10.1007/s12185-012-1171-1 7 0 1 15 Humans|Mice|Animals|*Multiple Myeloma|*DNA Copy Number Variations|*Genotype|Chromosomal Aberrations|Karyotyping|In Situ Hybridization, Fluorescence|Oligonucleotide Array Sequence Analysis|Prognosis|Loss of Heterozygosity|Single Nucleotide Polymorphism|Chromosome Deletion|Uniparental Disomies|Aneuploidy|Nucleotides 21 SEZ6L 22920719 J Affect Disord 2012 10.1016/j.jad.2012.07.017 6 0 4 15 Humans|*Bipolar Disorder|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|European Continental Ancestry Group|Case-Control Studies|*Epistasis, Genetic|*Seizure 21 SH3PXD2B 23140272 BMC Med. Genet. 2012 PMC3532175 10.1186/1471-2350-13-104 8 0 2 105 Humans|Child|Ter Haar syndrome|*Intracranial Pressure|*Craniofacial Abnormalities|*Osteochondrodysplasias|*Heart Defects, Congenital|*Developmental Disabilities|*Jaw Abnormalities|Hypertelorism|*Brachycephaly|Mutation|Adaptor Proteins, Signal Transducing|*Facial Bones 23 SH3PXD2B 22829589 J. Biol. Chem. 2012 PMC3438961 10.1074/jbc.M111.324897 12 4 3 105 Humans|Child|Ter Haar syndrome|*Epidermal Growth Factor|HeLa Cells|*Craniofacial Abnormalities|*Osteochondrodysplasias|*Heart Defects, Congenital|*Developmental Disabilities|*Cell Migration|TYRP1 protein, human|*Membrane Glycoproteins|Signal Transduction|Adaptor Proteins, Signal Transducing|src Tyrosine Kinases|Mutations|PI-3 Kinase|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one|Chromones|Phosphorylation 23 SH3PXD2B 22509100 Mol. Vis. 2012 PMC3324357 3 2 0 105 Mice|Adult|Animals|Humans|*Glaucoma|Eye Abnormalities|Anterior Eye Segment|Intraocular Pressure|*Tetrahymenina|Strain, Mutant Mouse|Mutations|*SH3 Domains|Pedigree|Phenotype|Forkhead Transcription Factors 23 SHROOM2 22634755 Nat. Genet. 2012 PMC4747430 10.1038/ng.2293 118 6 19 47 Humans|Genome-Wide Association Study|*Colorectal Cancer|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|Genetic Loci|Case-Control Studies|Asian Continental Ancestry Group|POLD3 protein, human|*DNA Polymerase III|*Risk|*Colonic Neoplasms 26 SHROOM2 22245343 Neuroimage 2012 PMC3312985 10.1016/j.neuroimage.2011.12.076 45 4 2 47 Humans|Adult|Aged|Alzheimer Disease 10|*Alzheimer Disease|*Cohort Studies|Single Nucleotide Polymorphism|Neuroimaging|Brain|Genetic Predisposition to Disease|Cognitive Impairment, Mild|Genome-Wide Association Study|Imaging, Magnetic Resonance|Endophenotype|Canada 26 SKOR1 22874913 Development 2012 PMC4074270 10.1242/dev.079442 6 1 0 30 Animals|Mice|*Drosophila|*Ecdysone|*Mushroom Bodies|ecdysone receptor|*Receptors, Steroid|SMAD2 protein, human|*Smad2 Protein|Drosophila Proteins|Drosophila melanogaster|Neurons|Gene Expression Regulation, Developmental|*Gene Expression|Signal Transduction|Central Nervous System|Larvae 24 SLC22A9 23251289 Exp Ther Med 2012 PMC3524273 10.3892/etm.2012.777 1 6 0 139 Animals|Mice|Dogs|multidrug resistance-associated protein 2|Resistance-Associated Protein, Multidrug|Organic Anion Transporters|mRNA|Glucose Transporter|Xenobiotics|Gene Chip|FABP1 protein, human|Fatty Acid-Binding Proteins|Transporters, Amino Acid|*Intestines|FABP2 protein, human|Slc3a1 protein, mouse|Amino Acid Transport Systems, Neutral|Amino Acid Transport Systems, Basic 30 SLC31A2 22794121 Curr Cancer Drug Targets 2012 10.2174/156800912803251199 20 0 2 125 Humans|Animals|*Platinum|*Antineoplastic Agents|Cisplatin|Carboplatin|Oxaliplatin|Organoplatinum Compounds|ATPase|Drug Resistance, Neoplasm|Copper-Transporting ATPases|Cation Transport Proteins|Tumors|Biological Transport|Copper 28 SLC31A2 22437668 Pharmacogenet. Genomics 2012 PMC3376193 10.1097/FPC.0b013e328352f436 13 0 1 125 *Paclitaxel|*Membrane Transport Proteins|Multigene Family|Polymorphism, Single Nucleotide|Cell Line, Tumor 28 SLC31A2 22332042 Adv Nutr 2012 PMC3065767 10.3945/an.110.000273 49 0 5 125 Humans|Animals|*Copper Transport Proteins|ATP7A protein, human|Copper-Transporting ATPases|Menkes Disease|Wilson Disease|Cation Transport Proteins|Adenosine Triphosphatases|Copper|*Mammals|Mutations|Homeostasis 28 SPAG16 23243203 J. Natl. Cancer Inst. 2012 PMC3691940 10.1093/jnci/djs503 13 0 0 28 Humans|White|African Americans|Genome-Wide Association Study|Genetic Predisposition to Disease|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Case-Control Studies|*Neuroblastoma|*Ethnic Groups|Odds Ratio|Risk Factors 28 SPAG16 22963137 BMC Urol 2012 PMC3487941 10.1186/1471-2490-12-27 0 0 0 28 Humans|Male|Mice|Animals|*Axonemes|*Sperm Motility|*WD40 Repeats|*Infertility, Male|*Asthenozoospermia|Sperm|Sperm Tail|*DNA Mutational Analysis|Testis|Cilia|Microtubule-Associated Proteins|Heterozygote|Mutation|SPAG16 protein, human 28 SPAG16 22403483 Biomark Insights 2012 PMC3290106 10.4137/BMI.S9003 8 0 0 28 Humans|*Real-Time PCR, Quantitative|In Situ Hybridization, Fluorescence|Oligodendroglioma|Astrocytoma|Glioma|Chromosome 1, monosomy 1p|Chromosome Deletion|Loss of Heterozygosity|Brain Neoplasms|DNA, Neoplasm|Prognosis|Chromosome Aberrations|Chromosomes, Human, Pair 1|SPOCK1 protein, human|Proteoglycans 28 SPANXA1 22737227 PLoS ONE 2012 PMC3380858 10.1371/journal.pone.0039088 8 4 0 37 Humans|*Embryonic Germ Cells|Pluripotent Stem Cells|Embryonic Stem Cells|Germ Cells|Induced Pluripotent Stem Cells|Genes, cdc|Cell Differentiation|Gene Expression Profiling|Genes, Regulator|Genome|*Genetic Profile|Embryo, Mammalian|Cell Cycle 27 SPOCK2 23029870 Acta Biomed 2012 1 0 0 42 Infant|Humans|Child|Infant, Newborn|Aged|*Genetic Predisposition to Disease|Respiratory Distress Syndrome, Newborn|Pulmonary Surfactants|Pulmonary Surfactant-Associated Protein C|Pulmonary Surfactant-Associated Protein B|*Lung|Bronchopulmonary Dysplasia|Pulmonary Surfactant-Associated Proteins|Mutations|Infant, Premature|Polymorphism, Genetic|ATP-Binding Cassette Transporters|Gestational Age|*Neonatal Diseases 35 srpx 22681909 Biomed. Pharmacother. 2012 10.1016/j.biopha.2012.04.001 27 1 4 33 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Oligonucleotide Array Sequence Analysis|Cell Proliferation|Downregulation|Up-Regulation|*Primary Cell Culture|Cell Movement|Gene Expression Profiling|*Phenotype|Neovascularization, Pathologic|RRAD protein, human|ras Proteins|ACTG2 protein, human|Actins 50 STK17B 23122956 Cell Rep 2012 10.1016/j.celrep.2012.09.028 0 34 0 215 *Signal Transduction|Receptors, Transforming Growth Factor beta|Receptor, Transforming Growth Factor-beta Type II|TGFB1 protein, human|Transforming Growth Factor beta1|Protein-Serine-Threonine Kinases|Transforming Growth Factor beta|Phosphorylation|Receptor, Transforming Growth Factor-beta Type I|*Carrier Proteins|DNA-Binding Proteins|Cell Line, Tumor|Protein Binding|Transfection|*Biological Processes 32 STK17B 23087808 Hematol Rep 2012 PMC3475941 10.4081/hr.2012.e19 0 16 0 215 Humans|*Multiple Myeloma|In Situ Hybridization, Fluorescence|Comparative Genomic Hybridization|DNA Copy Number Variations|*Ethnic Groups|*Translocation, Genetic|Chromosomal Aberration|*Genomics|Bone Marrow|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport|FBXL5 protein, human|Ubiquitin-Protein Ligase Complexes|F-Box Proteins|ATP8B4 protein, human|Adenosine Triphosphatases 32 STK17B 22506007 PLoS ONE 2012 PMC3323629 10.1371/journal.pone.0033770 65 1 8 215 *Idiopathic Pulmonary Fibrosis|Epigenesis, Genetic|DNA Methylation|Lung|Extracellular Matrix 32 STK40 23233723 J. Immunol. 2012 10.4049/jimmunol.1202695 46 6 7 141 Humans|*Keratinocytes|*RNA, Micro|Endothelial Cells|*Psoriasis|*Cytokines|Skin|CXCL8 protein, human|IL8|Signal Transduction|Chemokines|NF-kappa B|Gene Expression Regulation|Epidermis|CXCL5 protein, human|Chemokine CXCL5|CXCL1 protein, human|Chemokine CXCL1|Upregulation 24 STOML1 23082202 PLoS ONE 2012 PMC3474722 10.1371/journal.pone.0047736 1 23 0 71 FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|F-Box Proteins|CDK2 protein, human|*Cyclin-Dependent Kinase 2|Ubiquitin|Proteasome|Ubiquitin-Protein Ligases|Cell Cycle Proteins|Ubiquitination|Cullin 1|Cullin Proteins|Proteolysis|Protein Isoforms|Phosphorylation|Proto-Oncogene Proteins c-myc 20 STOML1 22729037 J Thorac Oncol 2012 10.1097/JTO.0b013e31824c9272 9 1 0 71 mesothelin|galectin-3, human|*Galectin 3|Mesothelioma, Malignant|*Mesothelioma|*GPI-Linked Proteins|*Lung Neoplasms|Pleural Neoplasms|*Pleural Effusions|Pleural Effusion, Malignant|Asbestosis|Biomarkers, Tumor|ROC Curve|*Peptides 20 STOML1 22308290 Blood 2012 PMC3824283 10.1182/blood-2011-09-382556 37 14 3 71 *Kinesin|SYT1 protein, human|*Synaptotagmin 1|Cytoplasmic Granules|Cytotoxic T-Lymphocytes|Immunological Synapses|Microtubule-Organizing Center|Secretory Vesicles|rab27 GTP-Binding Proteins|rab GTP-Binding Proteins|*Synapse|Microtubules|Protein Transport 20 TARBP1 22997707 Bioorg. Khim. 2012 10.1134/s1068162012030089 1 0 0 41 Humans|*Retroelements|Frequencies, Allele|Alu Elements|Alleles|Genome, Human|Polymorphism, Genetic|Mutagenesis, Insertional|Transcription, Genetic|Introns|*Acute Lymphoblastic Leukemia 26 TARBP1 22706980 Cell Tissue Res. 2012 10.1007/s00441-012-1446-0 14 0 3 41 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*miRNAs|RNA-Binding Proteins|*Nevus, Pigmented|DICER1 protein, human|Ribonuclease III|AGO2 protein, human|Argonaute Proteins|Gene Expression Regulation, Neoplastic|DEAD-box RNA Helicases|RNA, Messenger|*Neoplasms, Second Primary|SND1 protein, human|Nuclear Proteins|MTDH protein, human|Cell Adhesion Molecules 26 TBPL1 22928904 Andrologia 2012 10.1111/and.12008 17 0 1 1191 Humans|Male|Female|*Telomere|Telomere Shortening|*Reproduction|Spermatogenesis|Telomerase|Spermatozoa|Synapsis|Lifespan|Spermatogonia|Aging 28 tbxt 22984420 PLoS ONE 2012 PMC3439448 10.1371/journal.pone.0043330 4 15 0 369 Animals|*Mink|*Wnt Signaling Pathway|Xenopus laevis|Xenopus Proteins|Dishevelled Proteins|Wnt Proteins|Nik related kinase|Protein-Serine-Threonine Kinases|Adaptor Proteins, Signal Transducing|Phosphoproteins|Gastrulation|Embryo, Nonmammalian|Cell Polarity|Morphogenesis|Proteolysis|Intracellular Signaling Peptides and Proteins 75 tbxt 22820002 Mech. Dev. 2012 10.1016/j.mod.2012.07.001 5 2 0 369 Animals|*Xenopus laevis|*Zebrafish|*High Mobility Group Proteins|*Gastrulation|Mesoderm|Zebrafish Proteins|Body Patterning|Xenopus Proteins|Homeodomain Proteins|T-Box Domain Proteins|Goosecoid Protein|Transcription Factors|Gene Expression Regulation, Developmental|HMGB|Repressor Proteins|Trans-Activators|Gene Activation 75 tbxt 22813747 Cell Rep 2012 10.1016/j.celrep.2012.05.006 37 0 2 369 Animals|*Xenopus laevis|*Gastrulation|Histone Chaperones|Histone H3.3|Chromatin|Transcription Factors|Cell Cycle Proteins|Molecular Chaperones|Binding Sites|DNA Replication 75 tbxt 22662261 PLoS ONE 2012 PMC3360639 10.1371/journal.pone.0038009 8 29 2 369 Animals|*Xenopus laevis|*Blastula|GMNN protein, human|*Geminin|*Zygotes|Xenopus Proteins|Embryo, Nonmammalian|*Blastocyst|DNA Replication|Transcription Factors|DNA-Binding Proteins|G2 Phase|Gene Expression Regulation, Developmental|Blastomeres|Chromatin Assembly and Disassembly|Checkpoint Kinase 1|*Gene Expression|Cdt1 protein, Xenopus 75 TCF15 22701159 Sci Rep 2012 PMC3374161 10.1038/srep00455 25 22 1 58 Humans|*Chondrogenesis|*Pluripotent Stem Cells|*Mesoderm, Paraxial|Cell Differentiation|Bone Morphogenetic Proteins|Chondrocytes|Cartilage|Transforming Growth Factor beta|Bone Morphogenetic Protein 2|Signal Transduction|Proteoglycans|Cell Line|Activin|Cells, Cultured 39 TDRD3 23066109 Nucleic Acids Res. 2012 PMC3526276 10.1093/nar/gks929 10 9 0 132 N,N-dimethylarginine|*Arginine|Tudor Domain|Amino Acid Sequence|Protein Binding|Crystallography, X-Ray|Binding Sites|Methylation|Histones|Models, Molecular 25 TEX19 22447323 J. Reprod. Dev. 2012 10.1262/jrd.11-047k 3 0 1 48 Male|Mice|Female|Pregnancy|Animals|*Gonad|Testis|RNA-Binding Proteins|Spermatocytes|Nuclear Proteins|Mice, Knockout|Placenta|RNA, Messenger|Amino Acid Sequence|Ovary 20 tiprl 22841785 Gastroenterology 2012 10.1053/j.gastro.2012.07.103 18 8 3 1859 Humans|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|TIPRL protein, human|Intracellular Signaling Peptides and Proteins|JNK Mitogen-Activated Protein Kinases|Apoptosis|Cell Line, Tumor|Signal Transduction|*Cell Death 34 tiprl 22443683 FEBS J. 2012 10.1111/j.1742-4658.2012.08579.x 64 1 7 1859 Humans|*Protein Phosphatase 2|*Holoenzymes|Protein O-Methyltransferase|protein phosphatase methylesterase-1|Carboxylic Ester Hydrolases|*Biochemical Phenomena|Substrate Specificity|Signal Transduction|Methylation|leucine methyl ester|Leucine|Subunit, Catalytic 34 TMEFF1 22748014 Breast Cancer Res. 2012 PMC3680921 10.1186/bcr3217 34 13 1 69 Animals|*Signal Transduction|Receptors, Transforming Growth Factor beta|Transforming Growth Factor beta|Receptor, Transforming Growth Factor-beta Type II|Protein-Serine-Threonine Kinases|*Transforming Growth Factor|Fibroblasts|Cell Transformation, Neoplastic|Stromal Cells|Cell Movement|*Neoplastic Processes|Mammary Neoplasms, Experimental|Cell Line, Tumor|Neoplasm Invasiveness 26 TMEFF1 22226356 Cell Stem Cell 2012 PMC3349223 10.1016/j.stem.2011.11.005 122 24 7 69 Mice|Animals|*Hair Follicle|*Transforming Growth Factor beta|*Signal Transduction|Bone Morphogenetic Proteins|*Gene Expression Regulation|Stem Cells|SMAD2 protein, human|Smad2 Protein|SMAD4 protein, human|Smad4 Protein|Cells, Cultured|Cell Proliferation 26 TMEM135 22362584 J. Pathol. 2012 PMC4976800 10.1002/path.4003 23 0 2 40 Humans|Female|Breast Cancer, Familial|*Breast Neoplasms|BRCA1 protein, human|*BRCA1 Protein|Carcinoma, Ductal, Breast|Genes, BRCA1|Receptors, Estrogen|Germ-Line Mutation|Tumor Suppressor Proteins|Loss of Heterozygosity|Tumor Suppressor Protein p53|Mutations|Ovarian Cancer|Massively Parallel Sequencing|Estrogens|DAPK3 protein, human|Death-Associated Protein Kinases 20 TMEM163 23209189 Diabetes 2012 PMC3581193 10.2337/db12-0406 48 3 11 9 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|European Continental Ancestry Group|Genotype|Insulin Resistance|Odds Ratio 22 TMEM163 22507762 Prog. Neuropsychopharmacol. Biol. Psychiatry 2012 10.1016/j.pnpbp.2012.03.011 8 1 2 9 *Parkinson Disease|*Transcriptome|Receptors, Dopamine D3|Genetic Predisposition to Disease|*Psychotropic Drugs|Receptors, Dopamine D2|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies 22 TONSL 22895565 Int. J. Oncol. 2012 10.3892/ijo.2012.1589 4 3 0 109 Male|Animals|*Oncogene|RELA protein, human|Transcription Factor RelA|siRNA|*Lung|NF-kappa B|*Carcinogenesis|Esophageal Cancers|Lung Neoplasms|Cell Line, Tumor|DNA-Binding Proteins|cDNA Microarray|Apoptosis|Gene Knockdown Techniques|Cell Proliferation|Cell Nucleus|Gene Expression Profiling|Cell Cycle 28 tppp3 23053195 J. Mol. Evol. 2012 10.1007/s00239-012-9521-4 3 0 0 109 Humans|Animals|*Fishes|Vertebrate|Synteny|Gene Duplication|*Proteins|Evolution, Molecular|Amino Acid Sequence|Phylogeny|Genome|Sequence Alignment|Fish Proteins|Microtubule 22 TTI2 23142078 Mol. Cell 2012 PMC3545014 10.1016/j.molcel.2012.10.003 0 78 5 57 *mTORC1|*Dimerization|MTOR protein, human|TOR Serine-Threonine Kinases|Multiprotein Complexes|Monomeric GTP-Binding Proteins|Signal Transduction|Lysosomes|Carrier Proteins|Protein Binding|Tumor Suppressor Proteins|Amino Acids|Protein Transport|Glutamine|Stress, Physiological 25 UPK1A 23052694 J. Cancer Res. Clin. Oncol. 2012 10.1007/s00432-012-1317-9 10 0 1 118 Humans|Female|*Uterine Cervical Neoplasms|*Transcriptome|darapladib|*Oximes|*Benzaldehydes|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|PSMD4 protein, human|*Proteasome Endopeptidase Complex 66 UPK1A 23012359 J. Biol. Chem. 2012 PMC3501034 10.1074/jbc.M112.380287 10 2 1 118 Humans|Mice|Animals|*Uropathogenic Escherichia coli|*Pulmonary Surfactant-Associated Protein D|*Urinary Bladder|*Urinary Tract|Adhesins, Escherichia coli|Urinary Tract Infections|Uroplakin Ia|Urothelium|Fimbriae Proteins|Escherichia coli Infections|Pili, Bacterial|Bacterial Adhesions|*Epithelial Cells|Cell Line 66 VAX2 22357656 Hum. Mol. Genet. 2012 PMC3335318 10.1093/hmg/dds056 0 1 0 24 Animals|*PAX2 Transcription Factor|Zebrafish Proteins|Zebrafish|Coloboma, Ocular|Embryo, Nonmammalian|Morphogenesis|Eye|Transcription Factors|Gene Expression Regulation, Developmental|In Situ Hybridization 164 VIPAS39 23243155 Blood 2012 10.1182/blood-2012-10-459115 1 0 0 57 Humans|Megakaryocytes|Platelets|Cytoplasmic Granules|Secretory Vesicles|Vesicular Transport Proteins 24 VIPAS39 23002115 Blood 2012 PMC3538988 10.1182/blood-2012-05-431205 29 0 0 57 Humans|*Megakaryocytes|*Binding Protein|*Cytoplasmic Granules|Gray Platelet Syndrome|Arthrogryposis renal dysfunction cholestasis syndrome|Arthrogryposis|Platelet|Vesicular Transport Proteins|Secretory Vesicles|Cholestasis|Membrane Proteins|Renal Insufficiency|Endosomes|trans Golgi Network|*Hematopoiesis|VPS33B protein, human|NBEAL2 protein, human|Blood Proteins 24 VIPAS39 22753090 Hum. Mutat. 2012 PMC3746110 10.1002/humu.22155 19 6 0 57 Humans|Arthrogryposis renal dysfunction cholestasis syndrome|*Arthrogryposis|*Cholestasis|*Renal Insufficiency|*Phenotype|Vesicular Transport Proteins|*Protein Transport|Mutation|*Genotype|Donor Site, Splice|Kidney Diseases|Ichthyosis|Failure to Thrive 24 WDFY4 23249952 Eur. J. Hum. Genet. 2012 PMC3746253 10.1038/ejhg.2012.277 30 2 4 12 Humans|*Studies, Genome-Wide Association|*Asians|*European Continental Ancestry Group|*Lupus Erythematosus, Systemic|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Frequencies, Allele|Genotype|Alleles|Case-Control Studies|Ethnicity|Finland|Sweden|TNIP1 protein, human|DNA-Binding Proteins 20 WDFY4 22972472 Genes Immun. 2012 10.1038/gene.2012.33 12 0 1 12 Humans|Genome-Wide Association Study|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Asian|Polymorphism, Single Nucleotide|Alleles|*Downregulation|Intracellular Signaling Peptides and Proteins|Case-Control Studies|Gene Expression Regulation 20 WFDC1 22960155 Antiviral Res. 2012 PMC7114264 10.1016/j.antiviral.2012.08.012 3 0 0 69 Mice|Animals|*Murine hepatitis virus|*Neutrophils|HIV Infections|Mice, Inbred C57BL|Coronavirus Infections|Mice, Knockout|WFDC1 protein, human|Immunity, Innate|Disease Susceptibility|Macrophages|Lung|Gene Expression 42 ZC3H12D 22740462 Electrophoresis 2012 10.1002/elps.201100711 6 0 1 498 Male|hydrogen sulfite|*DNA Methylation|*Sulfites|CpG Islands|Epigenetic|Forensic Genetics|Nested PCR|Sequence Analysis, DNA|Semen|Cytosine|Genetic Markers|Saliva|Sperm|Body Fluids|High-Throughput Nucleotide Sequencing 20 ZC3H13 22366391 Mol. Biochem. Parasitol. 2012 10.1016/j.molbiopara.2012.02.006 10 0 0 158 Animals|*Trypanosoma brucei brucei|RNA, Protozoan|Protozoan Proteins|mRNA Degradation|RNA Interference|RNA, Messenger|Zinc Fingers|Amino Acid Sequence|Life Cycle 22 ZC3H13 22308454 Proc. Natl. Acad. Sci. U.S.A. 2012 PMC3289371 10.1073/pnas.1120542109 43 5 5 158 Animals|Humans|*RNA, Small Interfering|HEK293 Cells|NF-kappa B|TNF Receptor-Associated Factor 6|MAP3K8 protein, human|MAP Kinase Kinase Kinases|Signal Transduction|Viral Matrix Proteins|Interleukin-1 Receptor-Associated Kinases|Epstein Barr Virus|Protein Binding|Transfection|RNAi|Ubiquitin 22 ZC3H14 22614829 RNA Biol 2012 PMC3495735 10.4161/rna.20187 10 0 0 116 Animals|polyadenosine|*Intellectual Disability|Drosophila melanogaster|*Adenosine|*Polymers|Polyadenylation|RNA-Binding Proteins|Export, Nuclear|RNA, Messenger|RNA|Zinc Finger|Nuclear Proteins|Cell Nucleus|Fruit Fly, Drosophila|Neurons|Zinc 23 ZC3H14 22484098 Biochim. Biophys. Acta 2012 PMC3345082 10.1016/j.bbagrm.2012.03.006 19 26 1 116 Humans|Saccharomyces cerevisiae|polyadenosine|*mRNA|*Adenosine|Saccharomyces cerevisiae Proteins|Nucleocytoplasmic Transport Proteins|*Polymers|RNA, Fungal|Poly A Binding Proteins|Polyadenylation|Export, Nuclear|RNA-Binding Proteins|Zinc Finger|Cell Nucleus|NAB2 protein, human|Repressor Proteins|ZC3H14 protein, human|Nuclear Proteins 23 ZNF598 22751931 Mol. Cell. Biol. 2012 PMC3422012 10.1128/MCB.00455-12 49 2 2 133 Mice|Animals|Eukaryotic Initiation Factor-4E|RNA Cap-Binding Proteins|RNA Caps|mRNA|Protein Biosynthesis|*Mammals|Protein Binding|Carrier Proteins|Amino Acid Sequence 20 ZNF644 22783446 Oncol Lett 2012 PMC3392589 10.3892/ol.2012.669 9 0 1 140 Humans|*Transcriptome|Adriamycin|*Antineoplastic Agents|Nuclear Proteins|Tumor Suppressor Proteins|Carboplatin|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|*Leukocytes|DNA-Binding Proteins|DNA Damage|Cyclophosphamide|Upregulation|Prognosis|Cell Line, Tumor|Apoptosis|mRNA|Paclitaxel 20 ZNF644 22539872 Mol. Vis. 2012 PMC3335780 14 0 0 140 Humans|United States|*Myopia|Genetic Predisposition to Disease|Asian|Polymorphism, Single Nucleotide|*Cohort Studies|Exons|Transcription Factors|Mutation|European Continental Ancestry Group|Sequence Analysis, DNA|Asia|ZNF644 protein, human 20 ZNF91 22701369 ScientificWorldJournal 2012 PMC3373132 10.1100/2012/721313 3 1 0 55 Humans|*Gastrointestinal Stromal Tumors|Tomography, X-Ray Computed|Fluorodeoxyglucose F18|Positron-Emission Tomography|Radiopharmaceuticals|Neoplasm Proteins|Biomarkers, Tumor|*Information Storage and Retrieval 26 ABI3BP 21223585 BMC Cancer 2011 PMC3032749 10.1186/1471-2407-11-11 12 29 2 65 *Ectopic Gene Expression|*Cell Proliferation|*Cell Cycle|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Adaptor Proteins, Signal Transducing|Signal Transduction|Tumor Burden 27 ACAP2 22045739 J. Cell. Sci. 2011 10.1242/jcs.083881 31 2 3 127 *Phagocytosis|*Macrophages|Phagosomes|rab GTP-Binding Proteins|Receptors, IgG|ADP-Ribosylation Factors|GTPase Activating Protein|Cell Membrane|Cell Line|Protein Transport|Actin 26 ACRV1 21942998 Reprod. Biol. Endocrinol. 2011 PMC3192744 10.1186/1477-7827-9-128 5 3 2 6 Male|Mice|Animals|*Epididymis|*Testis|*Androgens|Amino Acid Sequence|Membrane Proteins|Prostate|Spermatozoa|Sequence Homology, Amino Acid|Multigene Family|RNA, Messenger 57 ACRV1 21488928 Andrologia 2011 10.1111/j.1439-0272.2010.01095.x 1 0 0 6 Male|Mice|Humans|Animals|Spermatogenesis|Testes|Spermatids|Spermatocytes|Oligonucleotide Array Sequence Analysis|ACRV1 protein, human|Membrane Proteins|Base Sequence|Amino Acid Sequence|cDNA|Gene Expression Regulation, Developmental|RNA, Messenger|BALB C Mice|Blotting, Western 57 ACRV1 21252238 J. Biol. Chem. 2011 PMC3064152 10.1074/jbc.M110.166587 26 5 0 6 Mice|Male|Animals|*Testis|*DNA Binding Protein|Spermatids|Spermatogenesis|Spermatocytes|Transcription, Genetic|Promoter Regions, Genetic|Histones|mRNA 57 ACRV1 21942998 Reprod. Biol. Endocrinol. 2011 PMC3192744 10.1186/1477-7827-9-128 5 3 2 6 Male|Mice|Animals|*Epididymis|*Testis|*Androgens|Amino Acid Sequence|Membrane Proteins|Prostate|Spermatozoa|Sequence Homology, Amino Acid|Multigene Family|RNA, Messenger 57 ACRV1 21488928 Andrologia 2011 10.1111/j.1439-0272.2010.01095.x 1 0 0 6 Male|Mice|Humans|Animals|Spermatogenesis|Testes|Spermatids|Spermatocytes|Oligonucleotide Array Sequence Analysis|ACRV1 protein, human|Membrane Proteins|Base Sequence|Amino Acid Sequence|cDNA|Gene Expression Regulation, Developmental|RNA, Messenger|BALB C Mice|Blotting, Western 57 ACRV1 21252238 J. Biol. Chem. 2011 PMC3064152 10.1074/jbc.M110.166587 26 5 0 6 Mice|Male|Animals|*Testis|*DNA Binding Protein|Spermatids|Spermatogenesis|Spermatocytes|Transcription, Genetic|Promoter Regions, Genetic|Histones|mRNA 57 ACTBP2 21873136 Forensic Sci Int Genet 2011 10.1016/j.fsigen.2011.07.015 2 0 0 0 *Alleles|*Germ-Line Mutation|Short Tandem Repeat|Paternity|*Mutations|Forensic Genetics|Genetics, Population|Rates, Mutation|Polymerase Chain Reaction|*Abdominal Muscles|*Abdominal Wall|Austria|Switzerland 67 ADAM29 22097694 Vnitr Lek 2011 1 0 0 13 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Prognosis|Biomarkers, Tumor|Mutation 31 ADAM29 22073229 PLoS ONE 2011 PMC3206881 10.1371/journal.pone.0026970 10 7 3 13 Humans|Mice|Animals|*Stomach Neoplasms|MUC1 protein, human|*Mucin-1|*Down-Regulation|Cell Proliferation|RNA Interference|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Adenocarcinomas|RNA, Small Interfering|Mice, Nude|Mucin 31 ADAM29 21618342 Hum. Mutat. 2011 PMC3103704 10.1002/humu.21477 17 6 0 13 Humans|*Disintegrins|Melanoma, Cutaneous Malignant|*Melanoma|ADAM Proteins|Skin Neoplasms|Cell Adhesion|Cell Movement|DNA Mutational Analysis|Cell Line, Tumor|Membrane Proteins|Gene Expression Regulation, Neoplastic|Gene Expression Regulation, Enzymologic|Mutations|Extracellular Matrix Proteins|ADAM29 protein, human 31 ADAM29 21526495 Folia Histochem. Cytobiol. 2011 10.5603/fhc.2011.0014 2 0 0 13 Humans|Male|*Leukemia, Lymphocytic, Chronic, B-Cell|*Prognosis|prostate apoptosis response-4 protein|*Apoptosis Regulatory Proteins|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|*Apoptosis|ZAP70 protein, human|ZAP-70 Protein-Tyrosine Kinase|Gene Expression Regulation, Leukemic|Upregulation|DAXX protein, human|Nuclear Proteins|Adaptor Proteins, Signal Transducing 31 ADAM7 21618342 Hum. Mutat. 2011 PMC3103704 10.1002/humu.21477 17 6 0 20 Humans|*Disintegrins|Melanoma, Cutaneous Malignant|*Melanoma|ADAM Proteins|Skin Neoplasms|Cell Adhesion|Cell Movement|DNA Mutational Analysis|Cell Line, Tumor|Membrane Proteins|Gene Expression Regulation, Neoplastic|Gene Expression Regulation, Enzymologic|Mutations|Extracellular Matrix Proteins|ADAM29 protein, human 24 ANKRD17 22190705 Biol. Reprod. 2011 PMC4480071 10.1095/biolreprod.111.095216 3 0 0 122 Male|Female|Mice|Animals|Meiosis|*Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome|Spermatocytes|Spermatids|Spermatogonia|Meiotic Prophase I|Pachytene Stage|Spermatogenesis|Testis|Prophase|Gene Expression|Gene Expression Profiling|In Situ Hybridization|Cell Nucleus 24 ANKRD17 21671165 J. Huazhong Univ. Sci. Technol. Med. Sci. 2011 10.1007/s11596-011-0368-5 1 2 0 122 Animals|Mice|*Muromegalovirus|IE3 protein, cytomegalovirus|*Immediate-Early Proteins|Viral Proteins|Gene Expression Regulation, Viral|DNA, Viral|Yeast Two-Hybrid Assay 24 ATL2 22194812 PLoS ONE 2011 PMC3241623 10.1371/journal.pone.0028175 17 1 2 95 *Mesenchymal Stem Cells|*Bone Marrow|*Pancreatic Islets|Cell Differentiation|Bone Marrow Cells|Insulin Secretion|Insulin-Secreting Cells|Insulin|C-Peptide|Cells, Cultured|*Hematopoiesis|Flow Cytometry|Phenotype 23 ATL2 22065636 J. Cell Biol. 2011 PMC3257528 10.1083/jcb.201105006 14 5 0 95 GTPase|Endoplasmic Reticulum|Guanosine Triphosphate|Membrane Fusion|Protein Conformation|Hydrolysis|Models, Molecular|Drosophila Proteins|Membrane Proteins|Protein Binding|*Biophysical Phenomena 23 BARHL1 22103894 BMC Evol. Biol. 2011 PMC3235082 10.1186/1471-2148-11-340 8 1 1 73 Animals|*Cell Lineage|Zebrafish|*Retina|Zebrafish Proteins|Homeobox|Amacrine Cell|Embryo, Nonmammalian|Homeodomain Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Oryzias|Sequence Alignment|Amino Acid Sequence|In Situ Hybridization 35 BARHL1 22027146 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.10.041 1 1 0 73 Mice|Animals|*Thyroid Hormones|Receptors, Thyroid Hormone|Binding Site|Promoter Regions, Genetic|Hypothyroidism|Gene Expression Regulation|Chromatin Immunoprecipitation|Transcription Factor|Transcription Start Site|Electrophoretic Mobility Shift Assay|Transfections|Protein Binding|Response Elements|Cerebellum|Barhl1 protein, mouse|Nerve Tissue Proteins|Repressor Proteins 35 BARHL1 21602885 Oncogene 2011 PMC5256860 10.1038/onc.2011.173 6 1 1 73 Adult|Animals|Mice|Humans|Child|*Medulloblastoma|Hedgehog Proteins|Cerebellar Neoplasms|Cerebellum|Repressor Proteins|Neurons|Barhl1 protein, mouse|Nerve Tissue Proteins 35 BARHL2 22143938 Tumour Biol. 2011 10.1007/s13277-011-0282-2 48 0 7 57 Humans|*DNA Methylation|*B-DNA|CpG Islands|*Lung Cancer|Adenocarcinomas|Squamous Cell Carcinomas|Oligonucleotide Array Sequence Analysis|Transcription Factors|Biomarkers, Tumor|Homeodomain Proteins|Genes, Homeobox|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|Sequence Analysis, DNA|DLX4 protein, human 30 BARHL2 22103894 BMC Evol. Biol. 2011 PMC3235082 10.1186/1471-2148-11-340 8 1 1 57 Animals|*Cell Lineage|Zebrafish|*Retina|Zebrafish Proteins|Homeobox|Amacrine Cell|Embryo, Nonmammalian|Homeodomain Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Oryzias|Sequence Alignment|Amino Acid Sequence|In Situ Hybridization 30 BARHL2 21262809 Proc. Natl. Acad. Sci. U.S.A. 2011 PMC3038765 10.1073/pnas.1014017108 10 6 0 57 Mice|Animals|CTNNB1 protein, human|*beta Catenin|AXIN2 protein, human|Axin Protein|Wnt Proteins|CASP3 protein, human|*Caspase 3|Xenopus laevis|Signal Transduction|Cell Proliferation|Xenopus Proteins|Proteins, Homeo Domain|Apoptosis|Cyclin D1|Cell Cycle|*Diencephalon|Barhl2 protein, mouse|Nerve Tissue Proteins 30 BLID 21846966 Cytogenet. Genome Res. 2011 PMC3214676 10.1159/000330265 2 0 0 49 Humans|Female|Adult|Middle Aged|Loss of Heterozygosity|Biomarkers, Tumor|DNA, Neoplasm|Genes, Tumor Suppressor|Tumor|Downregulation|BLID protein, human|Apoptosis Regulatory Proteins 187 BMP2K 22136433 J. Med. Chem. 2011 PMC3257585 10.1021/jm201286z 12 13 1 204 Humans|bauerine C|*Carbolines|Proto-Oncogene Proteins c-pim-1|Protein Kinase Inhibitors|Drug Screening Assays, Antitumor|Molecular Structure|Structure-Activity Relationship|Drug Discovery|Cell Line, Tumor|Antineoplastic Agents|Dose-Response Relationship, Drug|Models, Molecular|Cell Proliferation|Crystallography, X-Ray|Alkaloids|DAPK3 protein, human|Death-Associated Protein Kinases 23 BMP2K 22029166 Genet. Couns. 2011 0 0 0 204 Humans|Female|Aged, 80 and over|*Intellectual Disability|*Exotropia|*Hyperopia|*Tooth Eruption|*Dwarfism|Chromosome Deletion|Abnormalities, Multiple|Facies|Haploinsufficiency|Bone Diseases, Developmental|Tooth Abnormalities|Comparative Genomic Hybridization|Phenotype|Repressor Proteins|Dental Enamel|AMBN protein, human|Dental Enamel Proteins 23 BMP2K 21360476 J. Nephrol. 2011 10.5301/JN.2011.6382 4 0 0 204 Humans|*Diabetic Nephropathies|*Diabetes Mellitus, Type 2|Malaysia|End Stage Renal Disease|*Ethnic Groups|*Microarray Analysis|*Gene Expression Profiling 23 BRWD3 22024541 Exp. Mol. Med. 2011 PMC3277896 10.3858/emm.2012.44.1.003 15 0 2 50 Humans|Female|*Proteome|Proteomics|Biomarkers, Tumor|*Thrombospondin 1|Early Detection of Cancer|Neoplasm Recurrence, Local|Prognoses|Blotting, Western|Mass Spectrometry|Isotope Labeling, Stable|*Plasma|BRWD3 protein, human|Transcription Factors 25 BRWD3 21277957 Gene 2011 10.1016/j.gene.2010.12.013 1 0 0 50 Humans|*Promoter Regions, Genetic|Transcription Start Sites|Transcription, Genetic|Binding Sites|Conserved Sequence|Short Tandem Repeat|Transcription Factors|*Nucleotides|BRWD3 protein, human 25 C2CD4B 21909839 Diabetologia 2011 10.1007/s00125-011-2293-3 14 0 2 16 Humans|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|Japan|Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|SPRY2 protein, human|Membrane Proteins|Intracellular Signaling Peptides and Proteins|CDC123 protein, human|Cell Cycle Proteins|CAMK1D protein, human|Calcium-Calmodulin-Dependent Protein Kinase Type 1 24 C2CD4B 21887289 PLoS ONE 2011 PMC3161735 10.1371/journal.pone.0023639 17 9 1 16 Humans|*Insulin|*Proinsulin|*Glucose|Genome-Wide Association Study|*Insulin, Regular, Human|Blood Glucose|Genetic Loci|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Diabetes Mellitus, Type 2|Fasting|Asian Continental Ancestry Group|Genotype|Homeostasis 24 C2CD4B 21747906 PLoS ONE 2011 PMC3126830 10.1371/journal.pone.0021464 18 6 2 16 Humans|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|*Fasting|*Asian Continental Ancestry Group|Blood Glucose|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Prediabetic State|Genotype|CRY2 protein, human|Cryptochromes|GLIS3 protein, human|Transcription Factors 24 C2CD4B 21362171 BMC Dev. Biol. 2011 PMC3058101 10.1186/1471-213X-11-13 9 6 2 16 Mice|Animals|*Embryonic Stem Cells|pancreatic and duodenal homeobox 1 protein|*Homeodomain Proteins|*Trans-Activators|Endoderm|Cell Differentiation|Pancreas|DNA Microarray|Gene Expression Regulation, Developmental|Cell Line|Cells, Cultured|Gene Expression Profiling|Embryonic Development 24 C2CD4B 21249489 Diabetologia 2011 10.1007/s00125-010-2031-2 13 2 2 16 Humans|Genome-Wide Association Study|Diabetes Mellitus, Type 2|Denmark|Insulin Secretion|Insulin-Secreting Cells|Glucose Tolerance Test|Insulin|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Glucose|Alleles|Genotype|Case-Control Studies|VPS13C protein, human|Proteins 24 CDH16 22135066 Mol. Endocrinol. 2011 PMC5417163 10.1210/me.2011-1090 5 0 0 53 Mice|Animals|*Thyroid Gland|PAX8 protein, human|*PAX8 Transcription Factor|*Gene Expression Regulation|Paired Box Transcription Factors|Promoter Regions, Genetic|Transcription, Genetic|Thyroid Neoplasms|Binding Sites|RNA Interference|Cell Differentiation|Cell Line|Cadherins|Pax8 protein, mouse 48 CDH16 22028439 Endocrinology 2011 10.1210/en.2011-1572 9 1 1 53 Humans|Mice|Animals|*Thyroid Gland|*Thyroid Carcinomas|CDH1 protein, human|Cadherins|*Downregulation|Thyroid Carcinomas, Anaplastic|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Gene Expression Regulation, Neoplastic|RNA, Messenger|Epithelial-Mesenchymal Transition|Cell Differentiation|Cultured Cells|Antigens, CD 48 CDH22 21969168 Am J Cancer Res 2011 PMC3180053 3 0 0 30 Humans|Melanoma, Cutaneous Malignant|*Melanoma|Skin Neoplasms|Nevi, Dysplastic|Immunohistochemistry|Prognosis|Melanocytes|Biomarkers, Tumor|Tissue Array Analysis|Disease Progression|Cadherins|*Neoplasms, Second Primary|CDH22 protein, human 26 CDH22 21761482 Dev. Dyn. 2011 10.1002/dvdy.22686 8 0 0 30 Animals|Mice|osteoblast cadherin|Cadherins|Hindbrain|Mesencephalon|In Situ Hybridization|Gene Expression Regulation, Developmental|Brain|Amino Acid Sequence|RNA, Messenger|Cdh22 protein, mouse 26 CEND1 21596744 J. Biol. Chem. 2011 PMC3138307 10.1074/jbc.M110.210260 37 0 4 30 Mice|Animals|*Fragile X Syndrome|*Proteomics|FMR1 protein, human|Fragile X Mental Retardation Protein|*Synapses|*Hippocampus|Presynaptic Terminals|Mice, Knockout|*Disease Models, Animal|Excitatory Postsynaptic Potentials|Synaptic Vesicle|Growth Cones|*Phenotype|Fmr1 protein, mouse|Cend1 protein, mouse|Membrane Proteins|Nerve Tissue Proteins 26 CES1P1 21510813 Genet Test Mol Biomarkers 2011 10.1089/gtmb.2011.0010 1 1 0 5 Humans|*Asian Continental Ancestry Group|Gene Frequency|Single Nucleotide Polymorphism|Genotype|Allele|Promoter Regions, Genetic|Ethnic Groups|*Mutation|Lipids 20 CHD6 21931736 PLoS ONE 2011 PMC3172237 10.1371/journal.pone.0024515 41 21 5 261 Mice|Animals|Rats|*Chromatin Assembly and Disassembly|Mi-2 Nucleosome Remodeling and Deacetylase Complex|*Neurons|DNA Helicases|Nucleosomes|*Brain|ATPases|Cell Nucleus|HDAC2 protein, human|Histone Deacetylase 2|Transcription Factors|Neuroblastoma|Transcriptional Activation|Mta3 protein, mouse|Neoplasm Proteins 31 CHD6 21899694 Cell. Microbiol. 2011 10.1111/j.1462-5822.2011.01679.x 19 4 2 261 *Chromatin|*Influenza, Human|*Virus Replication|Influenza A virus|*Chromatin Assembly and Disassembly|Orthomyxoviridae|Viral Proteins|Ribonucleoproteins|Host-Pathogen Interactions|Cell Nucleus|Histone|DNA Helicases|Protein Binding|Cell Line 31 CLIC6 21692051 Cancer 2011 PMC3123690 10.1002/cncr.25818 39 8 5 37 Humans|*CpG Islands|*Carcinoma, Adenoid Cystic|*Salivary Gland Neoplasms|DNA Methylation|Gland, Salivary|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor 21 CLMN 22001116 Exp. Cell Res. 2011 10.1016/j.yexcr.2011.10.002 10 4 0 48 Animals|Mice|*Tretinoin|*Cell Cycle|*Neurite Outgrowth|Neuroblastoma|*Cell Division|Cell Differentiation|mRNA|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Neurites|Cell Proliferation|Cell Line, Tumor|*Regulatory Gene|Gene Expression Regulation, Neoplastic|*Neural Stem Cells 29 CLMN 21528012 Int J Mass Spectrom 2011 PMC3081587 10.1016/j.ijms.2010.11.001 1 1 1 48 *Spectrometry, Mass, Electrospray Ionization|*Lipids|*Atmospheric Pressure|*Steroids|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|*Laser|Ions|Androsterone|*Acoustic 29 COX6A2 21562175 J. Exp. Biol. 2011 10.1242/jeb.053322 3 0 0 26 Animals|*Electron Transport Complex IV|*Muscle, Skeletal|*Gene Expression|Transcription Factors|Gene Expression Regulation|Acclimatization|Mitochondria|mRNA|Goldfish|Cold|Cell Nucleus|DNA, Mitochondrial|Zebrafish 24 CPA6 21922598 Hum. Mutat. 2011 10.1002/humu.21613 9 1 2 44 Humans|*Seizures, Febrile|*Epilepsy, Temporal Lobe|*Mutations|Epilepsies, Partial|Genetic Linkage|Pedigree|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genotype|Carboxypeptidases 24 CRTAC1 21817055 Science 2011 PMC3244695 10.1126/science.1204144 25 8 1 35 Animals|Mice|*Lotus|*Axons|Nogo Receptor 1|Myelin Proteins|TYRP1 protein, human|Growth Cones|Nogo Proteins|Myelin-Associated Glycoprotein|Nerve Regeneration|Neurons|Tract, Lateral Olfactory|Calcium-Binding Proteins|GPI-Linked Proteins|Cells, Cultured|*Cartilage 27 CRYBB3 21873656 Invest. Ophthalmol. Vis. Sci. 2011 10.1167/iovs.10-7113 10 0 1 14 Cataract|Glaucoma|Retinal Diseases|Germany|Prevalence|Cross-Sectional Studies|Risk Factors|Surveys and Questionnaires 36 CRYBB3 21866213 Mol. Vis. 2011 PMC3159683 21 0 0 14 Humans|*DNA Mutational Analysis|*Cataract|gamma-Crystallins|*Chinese|Pedigree|Mutations|Genes, Dominant|Connexins|Base Sequence|Amino Acid Sequence|Mutation, Missense|Phenotype 36 CRYBB3 21436266 Invest. Ophthalmol. Vis. Sci. 2011 PMC3176079 10.1167/iovs.11-7168 4 0 0 14 Mice|Animals|Humans|*Mice, Transgenic|*Lens, Crystalline|Cataract, Autosomal Dominant|Cataract|gamma-Crystallins|*Lenses|RNA, Messenger 36 CRYBB3 22553694 Int J Ophthalmol 2011 PMC3340856 10.3980/j.issn.2222-3959.2011.04.20 16 0 0 14 *Cataracts|gamma-Crystallins|DNA Mutational Analysis|Pedigree|Mutation|Mutation, Missense|Genetic Loci 36 CRYZ 22028823 PLoS ONE 2011 PMC3197607 10.1371/journal.pone.0026156 13 40 2 488 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|*Down-Regulation|HDAC1 protein, human|*Histone Deacetylase 1|*Promoter Regions, Genetic|*Genotoxic Stress|Histone Deacetylases|Repressor Proteins|Transcription Factors|Transcription, Genetic|Cell Cycle|Adriamycin|Protein Binding|Apoptosis|Chromatin|Cell Line, Tumor|SIN3B protein, human 164 CSMD2 22064162 Psychiatr. Genet. 2011 PMC3241912 10.1097/YPG.0b013e32834acd07 50 3 5 9 *Genome-Wide Association Study|*Alcoholism|Depressive Disorder, Major|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Comorbidity|Case-Control Studies|Genotype|Phenotype|Diagnostic and Statistical Manual of Mental Disorders 20 CSMD2 21723258 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.06.121 9 0 2 9 Humans|*Transcriptional Activation|CpG Islands|DNA Methylation|*Pancreatic Cancer|Promoter Regions, Genetic|Gene Silencing|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Azacitidine|Upregulation|Cell Line, Tumor 20 CSMD2 21658281 BMC Cardiovasc Disord 2011 PMC3141757 10.1186/1471-2261-11-29 23 15 3 9 20 CSMD2 21439553 Biol. Psychiatry 2011 10.1016/j.biopsych.2011.01.030 58 0 7 9 20 DAZ3 21837945 Zhonghua Nan Ke Xue 2011 1 0 0 1 Male|Humans|*Sequence Tagged Sites|*Sertoli Cell-Only Syndrome|Oligospermia|Azoospermia|Chromosomes, Human, Y|Infertility, Male|Chromosome Deletion|PCR|*Asian Continental Ancestry Group 20 DAZ3 21735657 Zhonghua Nan Ke Xue 2011 2 0 0 1 Humans|Male|*Infertility, Male|Deleted in Azoospermia 1 Protein|Oligospermia|Chromosomes, Human, Y|Azoospermia|Chromosome Deletion|Haplotypes|Gene Deletion|RNA-Binding Proteins 20 DGCR2 21822266 Nat. Genet. 2011 PMC3196550 10.1038/ng.902 186 0 19 182 Humans|*Exome|*Schizophrenia|*Whole Exome Sequencing|Genetic Predisposition to Disease|Mutation|Exons|Pedigree|Sequence Analysis, DNA 22 DGCR2 21223309 Alcohol. Clin. Exp. Res. 2011 PMC3076804 10.1111/j.1530-0277.2010.01391.x 65 16 4 182 Pregnancy|Female|Humans|*DNA Methylation|*Neural Stem Cell|*Ethanol|*Cell Differentiation|Epigenesis, Genetic|Neurogenesis|Fetal Alcohol Spectrum Disorders|Cells, Cultured 22 DKKL1 21698294 PLoS ONE 2011 PMC3115956 10.1371/journal.pone.0020866 9 5 1 98 Male|Mice|Animals|Spermatogenesis|Acrosome|Sperm-Ovum Interactions|Fertilization|Testis|Blotting, Western|Amino Acid Sequence|Nuclear Proteins|Germ Cells|Meiosis 22 DLEU7 22020760 Cancer 2011 10.1002/cncr.26614 23 0 2 16 Humans|*Oxaliplatin|Genome-Wide Association Study|*Peripheral Neuropathy|*Colon Cancer|Organoplatinum Compounds|Leucovorin|Fluorouracil|Chemotherapy, Adjuvant|Antineoplastic Combined Chemotherapy Protocols|Polymorphism, Single Nucleotide|Genotype|Genetic Markers 23 DMRTA2 22023386 Genes Cells 2011 10.1111/j.1365-2443.2011.01555.x 13 0 1 12 Animals|*Zebrafish|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|*Telencephalon|NeuroD protein|*Neurogenesis|Nerve Tissue Proteins|NEUROG1 protein, human|Zebrafish Proteins|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Neurons|Embryonic Development|Cell Differentiation 25 dnajc10 21632540 J. Biol. Chem. 2011 PMC3137065 10.1074/jbc.M111.243998 12 1 1 331 Humans|Endoplasmic Reticulum-Associated Degradation|Endoplasmic Reticulum|Protein Folding|Membrane Proteins|Mannosidases|Glycosylation|Lectins|HEK293 Cells|EDEM1 protein, human 32 DNAJC14 21249176 PLoS Pathog. 2011 PMC3020928 10.1371/journal.ppat.1001255 34 18 3 65 Humans|Animals|*Flavivirus|Yellow fever virus|Virus Replication|Proteins, Viral Nonstructural|Molecular Chaperone|Host-Pathogen Interactions|RNA, Viral|Cell Line|Antiviral Agents|DNAJC14 protein, human|Fetal Proteins 20 DOC2A 22036572 Cell 2011 PMC3220409 10.1016/j.cell.2011.09.046 86 19 6 31 *Calcium|SYT1 protein, human|Synaptotagmin I|*Synaptic Transmission|Synaptic Vesicles|SNARE|Neurons|Membrane Fusion|Neurotransmitter|Exocytosis|Hippocampus|Patch-Clamp Techniques|Calcium-Binding Proteins|Action Potentials|Nerve Tissue Proteins|Protein Binding 42 DRAM2 21584698 Mol. Biol. Rep. 2011 10.1007/s11033-011-0835-x 16 5 2 31 *Autophagy|Tumor Suppressor Protein p53|Membrane Proteins|Apoptosis|Cell Line, Tumor|RNA Interference 21 DRP2 21753765 J. Hum. Genet. 2011 10.1038/jhg.2011.61 5 0 0 48 Humans|*Chromosome Deletion|Bruton type agammaglobulinemia|Agammaglobulinemia|Genetic Diseases, X-Linked|*Genetic Testing|*X Chromosome|Agammaglobulinaemia Tyrosine Kinase|Mutations|Intron|Exons|Protein-Tyrosine Kinases|Genome 49 DRP2 21461976 Plant Mol. Biol. 2011 10.1007/s11103-011-9773-1 9 0 2 48 *Arabidopsis|*Dynamin|Arabidopsis Proteins|*Endocytosis|*Plant Development|Gametophytes|Plant Roots|Plants, Genetically Modified|Cytokinesis|Plasma Membrane|DRP2B protein, Arabidopsis|GTP-Binding Proteins 49 EIF1AY 22158087 Hum. Reprod. 2011 10.1093/humrep/der421 9 0 1 31 Humans|Male|*Chromosomes, Human, Y|*Spermatocytes|Spermatogenesis|Azoospermia|Oligospermia|Testis|Spermatozoa|Gene Deletion|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 26 ENOSF1 21943404 Cell Biosci 2011 PMC3197473 10.1186/2045-3701-1-32 6 4 1 12 Animals|*Zebrafish|Zebrafish Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Gene Knockdown Techniques 23 ENOSF1 21735130 Cell Biochem. Biophys. 2011 10.1007/s12013-011-9232-2 4 1 0 12 Animals|Humans|*Pan troglodytes|*Glycogen Debranching Enzyme System|GSTM3 protein, human|*Glutathione S Transferase 3|*Glutathione S-Transferase pi|*Cerebrum|*Phosphopyruvate Hydratase|*Telencephalon|Regulatory Network, Gene|*Mannosidases|Cell Cycle|*Pyrophosphatases 23 EPB41L4B 21780101 Int. J. Cancer 2011 10.1002/ijc.26285 14 2 1 90 Humans|ezrin|*FERM Domains|*Osteosarcoma|*Multidrug Resistance|radixin|*Cytoskeletal Proteins|*P Glycoprotein|Bone Neoplasms|Drug Resistance, Neoplasm|moesin|Microfilament Proteins|Membrane Proteins|Cell Line, Tumor|Plasma Membrane|Gene Expression Regulation, Neoplastic|Actin|Cytoskeleton|*Amino Acids 23 EPB41L4B 21196246 Front Biosci (Landmark Ed) 2011 10.2741/3803 10 0 2 90 Humans|Cytoskeletal Proteins|Cytoskeleton|Microfilament Proteins|*Neoplastic Processes|Signal Transduction|Neurofibromin 2|Actin Cytoskeleton|*Cancer|Cell Movement|Cell Adhesion|Plasma Membrane|Extracellular Matrix 23 ERI3 22119218 Dig Liver Dis 2011 10.1016/j.dld.2011.10.003 4 0 0 23 Humans|*Lymph Node|*Colorectal Cancer|Lymphatic Metastasis|Lymph Node Excision|Neoplasm Staging|*Colonic Neoplasms|Registries|France 25 ERI3 22118184 Int. J. Tuberc. Lung Dis. 2011 PMC3399785 10.5588/ijtld.11.0008 1 0 0 23 *Asbestos|*Multiple Pulmonary Nodules|Mesothelioma|Pleural Neoplasms|*Tomography, X-Ray Computed|Asbestosis|Lung Neoplasms|Pleura|Occupational Exposure 25 ERI3 21980622 Anal. Quant. Cytol. Histol. 2011 1 0 0 23 *Lung Cancer|Carcinoma, Bronchogenic|*Bronchi|Adenocarcinoma|Carcinoma, Squamous Cell|Bronchoscopy|*Sensitivity and Specificity|Sputum|Mass Screening|Cell Nuclei 25 ERI3 21852699 J Med Screen 2011 10.1258/jms.2011.011012 1 0 1 23 *Occult Blood|Guaiac|*Colorectal Cancer|Early Detection of Cancer|Colonoscopy|Immunochemistry|Mass Screening|Feces|*Colonic Neoplasms|Hemoglobin|Risk Factors|Microsurgery 25 ERI3 21724747 Thorax 2011 10.1136/thoraxjnl-2011-200172 10 0 1 23 *Asbestos|*Pleural Diseases|Asbestosis|*Pulmonary Fibrosis|Vital Capacity|Lung|Forced Expiratory Volume|Occupational Exposure|Smoking|*Radionuclide Imaging|Tomography, X-Ray Computed|Fibrosis 25 ERI3 21576271 Cancer Epidemiol. Biomarkers Prev. 2011 10.1158/1055-9965.EPI-10-0594 6 0 1 23 *Occult Blood|*Early Detection of Cancer|*Colorectal Neoplasms|Immunochemistry|Colonoscopy|Mass Screening 25 ERI3 21539283 Med Sci Law 2011 10.1258/msl.2010.010037 0 0 0 23 Humans|Assisted Suicide|*Rights, Patients'|Terminal Care|Europe|France|Pain 25 ERI3 21530429 Dig Liver Dis 2011 10.1016/j.dld.2011.03.003 5 0 1 23 Humans|*Occult Blood|*Colonoscopy|Colorectal Cancer|Mass Screening|Patient Compliance|*Geography 25 ERI3 21406385 Occup Environ Med 2011 10.1136/oem.2010.059790 10 0 1 23 *Incidence|*Asbestos|Mesothelioma|*Cohort Studies|Occupational Exposure|Pleural Neoplasms|Occupational Diseases|Peritoneal Neoplasms|Lung Neoplasms 25 ERI3 21256688 Rev Epidemiol Sante Publique 2011 10.1016/j.respe.2010.10.008 2 0 0 23 Humans|*Patient Navigation|*Cancer|Socioeconomic Factors|Inequality, Healthcare|France|Social Class|Social Justice|Poverty|Industrialized Countries 25 ERMN 21947165 J. Mol. Med. 2011 10.1007/s00109-011-0818-3 0 1 0 57 Humans|*Hydroxymethylglutaryl-CoA Reductase Inhibitors|Atorvastatin|Heptanoic Acids|Hypercholesterolemia|Cholesterol, LDL|Anticholesteremic Agents|Pyrroles|Cholesterol, HDL|*Biomarkers|Familial Hypercholesterolemia|Lipids 24 ERMN 21221725 Mol. Cell. Biochem. 2011 10.1007/s11010-010-0696-y 0 4 0 57 *Cell Differentiation|Oligodendrocyte|*Promoter Regions, Genetic|Transcription Factors|*Gene Expression Regulation|Homeodomain Proteins|Myelin Sheath|Zebrafish Proteins|Nerve Tissue Proteins|Gene Expression|Transcriptional Activation|5' Flanking Region|Protein Binding|Cell Line 24 ETV3 22028470 Sci Signal 2011 PMC3779841 10.1126/scisignal.2002010 52 51 2 1655 Animals|MAPK1 protein, human|*Extracellular Signal Regulated Kinase 2|Mitogen-Activated Protein Kinase 3|Phosphorylation|*Gene Expression Regulation|DNA-Binding Proteins|Transcription Factors|ets-Domain Protein Elk-1|Binding Sites|Mitogen-Activated Protein Kinases|Protein Binding|Promoter Regions, Genetic|Amino Acid Sequence|DNA|Adenosine Triphosphate 23 ETV3 21318373 Virchows Arch. 2011 10.1007/s00428-011-1053-6 5 0 2 1655 Humans|*Transcription Factors|*Colorectal Cancer|Prognosis|Tumor Staging|Neoplasm Invasiveness|Biomarkers, Tumor|Immunohistochemistry|Adenocarcinoma|Lymphatic Metastasis|Proto-Oncogene Proteins c-ets|Real Time Polymerase Chain Reaction|RNA, Messenger|*Colonic Neoplasms|Cellular Proliferation|Tumor Cells, Cultured|Apoptosis|ETV3 protein, human 23 EVX2 22143938 Tumour Biol. 2011 10.1007/s13277-011-0282-2 48 0 7 14 Humans|*DNA Methylation|*B-DNA|CpG Islands|*Lung Cancer|Adenocarcinomas|Squamous Cell Carcinomas|Oligonucleotide Array Sequence Analysis|Transcription Factors|Biomarkers, Tumor|Homeodomain Proteins|Genes, Homeobox|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|Sequence Analysis, DNA|DLX4 protein, human 33 EVX2 21507233 BMC Cancer 2011 PMC3098185 10.1186/1471-2407-11-147 41 0 1 14 *Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Promoter Regions, Genetic|Calcium-Calmodulin-Dependent Protein Kinases|Death-Associated Protein Kinases|DNA Methylation|Tumor Suppressor Proteins|Apoptosis Regulatory Proteins|Lung|Class I Phosphatidylinositol 3-Kinases 33 FAIM3 21908732 J. Immunol. 2011 PMC3186823 10.4049/jimmunol.1100532 32 25 2 72 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|CD8-Positive T-Lymphocytes|B-Lymphocytes|*Downregulation|*Signal Transduction|Lymphocyte Activation|Receptors, Fc|*Carrier Proteins|Immunoglobulin M|*Lysosome|NK Cells|Membrane Proteins|Immunofluorescence|Complexes, Immune 23 FAIM3 21323829 Cell. Microbiol. 2011 10.1111/j.1462-5822.2011.01574.x 2 0 0 72 Rats|Animals|*Plasmodium berghei|Malaria|Parasitemia|Spleen|Adoptive Transfer|Immune Responses, Cellular|Flow Cytometry|Cytokines 23 FAIM3 21264533 Med. Oncol. 2011 10.1007/s12032-011-9821-3 4 0 1 72 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Receptors, Opioid, mu|ADP-ribosyl Cyclase 1|Prognosis|B-Lymphocytes|Apoptosis Regulatory Proteins|Chromosomal Abnormalities|Lymphocytes|Disease Progression|mRNA|Membrane Proteins|immunoglobulin M receptor 23 FASTK 21278888 J Gynecol Oncol 2011 PMC3026305 10.3802/jgo.2010.21.4.255 1 1 0 83 Humans|Female|*Cisplatin|*Ovarian Cancer|*Carcinoma, Ovarian Epithelial|*Apoptosis|Drug Resistance, Neoplasm|Antineoplastic Agents|Caspases|Caspase 3|Cell Line, Tumor|RNA, Messenger 24 FASTKD2 22166141 Tissue Eng Part C Methods 2011 PMC3358099 10.1089/ten.TEC.2011.0508 8 0 1 49 Humans|*Wharton Jelly|*Wharton Jelly Cells|*Cell Survival|Umbilical Cord|*Cell Therapy|Cell Differentiation|Cells, Cultured|Cell Proliferation|Tissue Engineering|Apoptosis|FASTKD2 protein, human|Protein-Serine-Threonine Kinases|TNFAIP8 protein, human|Apoptosis Regulatory Proteins 22 FASTKD2 21444724 Mol. Cell. Biol. 2011 PMC3133243 10.1128/MCB.01381-10 23 10 1 49 Humans|Sexual Maturation|IRF2BP2 protein, human|Nuclear Proteins|*Apoptosis|Transcription Factors|Carrier Proteins|Caspase 2|DNA-Binding Proteins|Cell Line, Tumor|Transcription, Genetic|MCF-7 Cells|Chromatin Immunoprecipitation|Protein Binding|FASTKD2 protein, human|Protein-Serine-Threonine Kinases 22 Fcrla 22078318 Cell. Immunol. 2011 PMC3250215 10.1016/j.cellimm.2011.10.013 2 5 0 38 Mice|Animals|B Cells|Tissues, Lymphoid|IgA receptor|Receptors, Fc|Immunoglobulin M|Receptors, Immunologic|Lymphocyte Activation|Immunoglobulin G|Cell Differentiation|Flow Cytometry 27 FILIP1 21997104 Opt Express 2011 10.1364/OE.19.020953 0 0 0 40 *Glass|Laser|Light|Equipment Design 22 FILIP1 21784850 J. Biol. Chem. 2011 PMC3173115 10.1074/jbc.M111.255851 12 3 0 40 *Filamins|*Transcription Factors|*Heat Shock|DNA-Binding Proteins|Heat Shock Transcription Factors|Proteasome|Protein Binding|Carrier Proteins|Ubiquitination|*Cell Line|Ubiquitin|Acetylation|Promoter Regions, Genetic|Isoforms|Cell Differentiation 22 FILIP1 21693594 Mol. Cancer Res. 2011 PMC3157597 10.1158/1541-7786.MCR-11-0162 13 8 0 40 Humans|Female|*Down-Regulation|*Filamins|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|CpG Island|*Promoter Regions, Genetic|DNA Methylation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Azacitidine|Carrier Proteins|Cytoskeletal Proteins|*Phenotype 22 FILIP1 21513424 Hum. Gene Ther. 2011 10.1089/hum.2011.047 6 0 0 40 Humans|Mice|Animals|Female|*Polyethyleneimine|*Nanogels|*Heparin|Mice, Nude|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Transfections|*Cations|Gene Transfer Techniques|Apoptosis|Cell Proliferation|Genetic Therapy|Cell Line, Tumor|Xenograft Model Antitumor Assays|Polyethylene Glycols|Neovascularization, Pathologic|FILIP1L protein, human|Intracellular Signaling Peptides and Proteins 22 FJX1 21903076 Neuron 2011 PMC3521586 10.1016/j.neuron.2011.06.026 37 7 6 72 Animals|Amacrine Cells|Retina|Dendrites|*Cadherins|Neurites|Gene Expression Regulation, Developmental|Luminescent Proteins|Animals, Newborn 26 FJX1 21381034 J. Pathol. 2011 10.1002/path.2856 44 0 1 72 Humans|Mice|Animals|Potter Type III Polycystic Kidney Disease|*Disease, Polycystic Kidney|Polycystic Kidney, Autosomal Dominant|TRPP Cation Channels|*Signal Transduction|Kidney|Kidney Tubules|Cell Polarity|Cell Proliferation|Apoptosis|Disease Models, Animal|End Stage Renal Disease|Disease Progression|Hippo protein, human|Protein-Serine-Threonine Kinases|FJX1 protein, human|Membrane Proteins 26 FKBP11 21600883 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.04.136 20 4 0 61 *Membrane Protein|*Osteoblast|Membrane Glycoproteins|Tetraspanin 29|Tetraspanin 28|tacrolimus binding protein 5|Tacrolimus Binding Proteins|Bone Formation|Antigens, CD|Tumor Cells, Cultured|Interferon 21 foxd4 21948691 Am. J. Med. Genet. A 2011 PMC3428835 10.1002/ajmg.a.34168 3 0 0 58 Humans|Adolescent|Chromosome 20, trisomy|Trisomy 20p|*Trisomy|Chromosome 9p Deletion Syndrome|*Chromosome Deletion|*Comparative Genomic Hybridization|*Maternal Inheritance|*Chromosomes, Human, Pair 9|*Chromosomes, Human, Pair 20|Monosomy|Duplication, Chromosome|Abnormalities, Multiple|Abnormal Karyotype|In Situ Hybridization, Fluorescence|Mosaicism|DOCK8 protein, human|Guanine Nucleotide Exchange Factors 27 foxd4 21482378 Taiwan J Obstet Gynecol 2011 10.1016/j.tjog.2011.01.038 1 1 0 58 Pregnancy|Female|Humans|*Comparative Genomic Hybridization|*In Situ Hybridization, Fluorescence|*Prenatal Diagnosis|Amniocentesis|Karyotyping|Trisomy|Chromosome Deletion|Chromosome Inversion|*Cytogenetics 27 FOXN2 21531217 Clin. Biochem. 2011 10.1016/j.clinbiochem.2011.04.006 3 4 0 138 28 FOXN2 21303847 Development 2011 PMC3035096 10.1242/dev.058396 14 3 1 138 28 GAGE1 22096562 PLoS ONE 2011 PMC3212555 10.1371/journal.pone.0027362 12 32 2 20 *Carcinoma, Hepatocellular|PTK2B protein, human|*Focal Adhesion Kinase 2|*Cisplatin|*Liver Neoplasms|Cell Proliferation|Cell Line, Tumor|Apoptosis|Cell Movement 48 GBX1 21381151 Stem Cells 2011 PMC3107131 10.1002/stem.626 63 16 4 17 34 GBX1 21360792 Dev. Dyn. 2011 10.1002/dvdy.22589 6 0 0 17 34 GIMAP4 21925515 Life Sci. 2011 PMC3264544 10.1016/j.lfs.2011.08.016 3 6 0 68 Rats|Animals|*Rats, Inbred BB|*B Cells|Lymphopenia|T-Lymphocytes|*Gene Expression|Diabetes Mellitus, Type 1|GTP-Binding Proteins|*Cell Count|Gimap5 protein, rat 29 GLIPR2 22133690 Biol. Reprod. 2011 10.1095/biolreprod.111.095760 53 0 9 52 Humans|Male|*Prostate|*Annexin A1|Sperm Motility|Seminal Plasma|PSCA protein, human|*Neoplasm Proteins|Spermatozoa|Epididymis|*GPI-Linked Proteins|*Membrane Proteins|Testes|Exosomes|Cells, Epithelial|Reproduction|Stem Cells 21 glycolisis 22202034 Front Biosci (Elite Ed) 2011 10.2741/539 10 0 1 0 *Cholestasis|Liver|Mitochondria, Liver|Oxidative Stress|Mitochondria|Biliary Cirrhosis|Bile Acids|Oxidation-Reduction|Liver Disease|DNA, Mitochondrial|Fibrosis 23 glycolisis 22127328 Exp. Parasitol. 2011 10.1016/j.exppara.2011.11.001 0 0 0 0 Humans|Mice|Animals|*Cysticercus|*Taenia|Albendazole|Prasiquantel|Cysticercosis|Anthelmintics|Tricarboxylic Acid Cycle|*Carboxylic Acids|Energy Metabolism|Glycolysis|Metabolic Pathways|Mice, Inbred BALB C|Oxaloacetate|Glucose|malic acid|Malates|Succinate 23 glycolisis 21735096 Mol. Cell. Biochem. 2011 10.1007/s11010-011-0950-y 12 1 0 0 Humans|Female|CIGB-300|*Proteomics|*Synthetic Drug|*Peptides, Cyclic|*Peptides|Apoptosis|Cell Proliferation|Casein Kinase II|Phosphorylation|nucleophosmin|Nuclear Proteins|Cell Line, Tumor|*Protein Processing, Post-Translational|Cell Nucleolus|Uterine Cervical Neoplasms|Cell Nucleus 23 GPR26 21924326 Neuroscience 2011 10.1016/j.neuroscience.2011.08.069 18 1 1 71 Humans|Animals|Mice|Rats|*Central Amygdaloid Nucleus|*Phosphorylation|*Depression|*Cyclic AMP Response Element-Binding Protein|*Anxiety|Maze Test|Neuropeptide Y|*Anxiety Disorders|Alcohol Drinking|Signal Transduction|Memory|Mice, Knockout|Cyclic AMP|Gpr26 protein, rat|Receptors, G-Protein-Coupled 20 GPR64 22069496 PLoS ONE 2011 PMC3206077 10.1371/journal.pone.0027127 18 8 3 39 Humans|Male|Mice|Animals|*Spermatogenesis|Spermatozoa|Testis|Infertility, Male|Sperm Motility|Mice, Knockout|Proteins|Gene Expression|MLL5 protein, human|MLL5 protein, mouse|Histone-Lysine N-Methyltransferase 28 GPR64 21712773 Neuro Endocrinol. Lett. 2011 4 0 0 39 *RNA, Small Interfering|*Schizophrenia|*RGS Proteins|*Gene Silencing|*Genetic Profile|*RNA, Double-Stranded|Signal Transduction 28 GPR85 21395347 J. Proteome Res. 2011 10.1021/pr101252p 2 0 0 29 Cricetinae|Animals|Mice|Cricetulus|CHO Cells|GPRC5C protein, human|*Receptors, G-Protein-Coupled|Mass Spectrometry|Amino Acid Sequence|*Gas Chromatography-Mass Spectrometry|Proteomics|Forebrains|Isotope Labeling, Stable|Peptides 25 GRIN3B 22195173 AMIA Annu Symp Proc 2011 PMC3243134 9 0 0 31 *Schizophrenia|Antipsychotic Drugs|Receptors, N-Methyl-D-Aspartate|*Drug Interactions|Network, Gene|Epistasis, Genetic 21 GRIN3B 22833210 Transl Psychiatry 2011 PMC3309470 10.1038/tp.2011.52 67 4 9 31 Humans|*N Methyl D Aspartate Receptors|*Autism Spectrum Disorder|*N-Methylaspartate|*Glutamate|*Schizophrenia|*Mutations|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Case-Control Studies|Cohort Studies|Intellectual Disability 21 HMG20B 21606163 Haematologica 2011 PMC3166094 10.3324/haematol.2011.045211 8 4 0 74 *Cell Differentiation|Erythroid Cells|GATA1 Transcription Factor|Repressor Proteins|Transcription Factor|Erythroblasts|Erythropoiesis|Histone Demethylases|Promoter Regions, Genetic|Gene Expression Regulation|Proto-Oncogene Proteins|Nerve Tissue Proteins|Protein Binding|DNA 22 HMG20B 21399666 Oncogene 2011 PMC3145889 10.1038/onc.2011.55 11 22 0 74 Humans|BRCA2 protein, human|*BRCA2 Protein|Rad51 Recombinase|*High Mobility Group Proteins|Repetitive Sequences, Amino Acid|DNA Damage|Protein Binding|Amino Acid Sequence|Sequence Alignment|Cytokinesis 22 HMGN3 22150271 Biochem. J. 2011 PMC3713072 10.1042/BJ20111502 8 45 0 72 *Chromatin|*Acetylation|histone H3 trimethyl Lys4|*Histones|*Binding Protein|HMGN3 protein, human|*HMGN Proteins|Nucleosomes|HMGN1|*Protein Processing, Post-Translational|HMGN2|Binding Sites|Protein Binding|Gene Expression|Promoter Regions, Genetic 28 HMGN3 21947420 Hum. Genet. 2011 PMC4450081 10.1007/s00439-011-1093-7 3 2 0 72 Humans|Female|*Genome-Wide Association Study|*Chinese|Single Nucleotide Polymorphism|European Continental Ancestry Group|HMGN3 protein, human|*HMGN Proteins|Haplotype|Bone|Ethnic Groups|Study, Followup 28 HMGN3 21897848 PLoS ONE 2011 PMC3163650 10.1371/journal.pone.0023604 17 1 0 72 Female|Animals|Mice|*Cathepsin B|*Anxiety|*Transcriptome Analysis|Mice, Knockout|*Anxiety Disorders|Behavior, Animal|Disease Models, Animal|Brain|*Phenotype|HMGN3 protein, mouse|HMGN Proteins 28 HTATSF1 21282347 RNA 2011 PMC3062177 10.1261/rna.2462011 10 1 0 139 *Exon|*RNA Splicing|Alternative Splicing|Oligonucleotide Array Sequence Analysis|HIV-1|Gene Expression|Transcription Factor|Gene Expression Profiling|RNA, Messenger|RNAi|Cell Cycle 26 INSL4 21874386 Mamm. Genome 2011 10.1007/s00335-011-9355-1 17 0 3 17 Animals|Humans|Female|Pregnancy|*Retroelements|*DNA Methylation|Promoter Regions, Genetic|Placenta|Epigenesis, Genetic|Exon 45 insl6 22033292 Anal. Biochem. 2011 10.1016/j.ab.2011.09.031 4 0 0 28 Animals|Guinea Pigs|Muscle, Smooth|Muscle Contraction|Ileum|peptide B|Enkephalins 40 IRGC 22048228 Clin. Pharmacol. Ther. 2011 10.1038/clpt.2011.231 4 0 0 17 *Drugs, Nonprescription|*Benefit-Risk Assessment|Risk Management|Prescription Drugs 32 IRGC 21988826 Cereb. Cortex 2011 10.1093/cercor/bhr284 58 0 8 17 Animals|Pregnancy|Female|*Ferrets|*Kinetics|Neurogenesis|Cerebral Cortex|Neural Stem Cells|Subventricular Zone|Neuroglia|Neurons|Primates|Cell Cycle|Cell Division 32 IRGC 21970567 Phytopathology 2011 10.1094/PHYTO-03-11-0075 11 0 3 17 *Xanthomonas|Xanthomonas oryzae|Disease Resistance|Oryza|Chromosome Mapping|Crosses, Genetic|Quantitative Trait Loci|Chromosomes, Plant|Plant Diseases|Genes, Plant|Genetic Linkage|Genetic Markers|Microsatellite Repeats|Breeding|Phenotype 32 IRGC 21446401 Ambio 2011 PMC3357789 10.1007/s13280-010-0134-0 10 0 0 17 *Uncertainty|*Adaptation, Psychological|Risk Management|Risk Assessment|*Governments|Policy Making 32 ISL2 22183394 Adv. Exp. Med. Biol. 2011 10.1007/978-1-4614-0631-0_87 1 5 0 74 Animals|Mice|*Genes, Homeobox|*Retinal Ganglion Cell|*Cell Differentiation|Homeodomain Proteins|Transcription Factors|Retina|Axons|Gene Expression Regulation, Developmental|Interneurons|EPHB2 protein, human|Receptor, EphB2|neuropilin-2, human|Neuropilin-2|Cell Movement|*Neurogenesis|Vax1 protein, mouse|Neuropeptides 55 ISL2 22025611 J. Biol. Chem. 2011 PMC3234805 10.1074/jbc.M111.248559 22 3 2 74 Lhx3 protein|*LIM-Homeodomain Proteins|*Transcription Factors|DNA-Binding Proteins|LIM Domain Proteins|Motor Neurons|Protein Binding|Neurogenesis|Mutagenesis 55 ISM1 21565795 J. Clin. Endocrinol. Metab. 2011 10.1210/jc.2010-2143 22 0 5 121 CTNNB1 protein, human|*beta Catenin|*Adrenal Cortex Neoplasms|Adrenocortical Carcinomas|Adrenocortical Adenomas|Wnt Proteins|*Mutations|Signal Transduction|Cell Line, Tumor 26 KLF16 22203677 J. Biol. Chem. 2011 PMC3293586 10.1074/jbc.M111.266007 17 29 0 93 Kruppel-Like Transcription Factors|CHUK protein, human|*I-kappa B Kinase|Repressor Proteins|Signal Transduction|Chromatin|Gene Silencing|Binding Sites|Acetyltransferase, Histone 26 LGALS12 21969596 Proc. Natl. Acad. Sci. U.S.A. 2011 PMC3219109 10.1073/pnas.1109065108 19 0 1 461 Humans|Animals|Mice|*Lipolysis|*Insulin Resistance|*Adiposity|*Galectin|*Adipocytes|3T3-L1 Cells|Insulin|Signal Transduction|*Obesity|Cyclic AMP-Dependent Protein Kinases|Cyclic AMP|Triglycerides|Lipid Metabolism|Cell Cycle Proteins 24 LGALS12 21702482 J Chem Inf Model 2011 10.1021/ci200180h 9 0 1 461 Female|Pregnancy|Animals|Humans|LGALS13 protein, human|*Galectin|Binding Sites|Galectin 4|Ligands|Protein Binding|Protein Conformation|Protein Structure, Tertiary|poly-N-acetyllactosamine|Polysaccharides|Carbohydrate|Amino Acid Sequence|Pregnancy Proteins|Simulations, Molecular Dynamics|Glycoconjugates|Sequence Homology, Amino Acid 24 LHX5 21860224 Brain Behav. Evol. 2011 10.1159/000330056 23 0 1 58 Mice|Animals|*Prosencephalon|*Amygdala|LIM-Homeodomain Proteins|Homeodomain Proteins|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Transcription Factors|Gene Expression Regulation, Developmental|Septal Nuclei|Nerve Tissue Proteins|Neurons|Lhx9 protein, mouse|Lhx2 protein, mouse 61 LRWD1 21775310 Bioinformatics 2011 10.1093/bioinformatics/btr426 12 0 0 85 Animals|Humans|*Phosphorylation|*Pan troglodytes|Protein Kinases|Amino Acid Sequence|Cyclin-Dependent Kinases|Binding Sites|Signal Transduction|Phosphoproteins|Bioinformatics 22 LRWD1 21586903 Epigenetics 2011 10.4161/epi.6.6.16179 21 0 1 85 Humans|Animals|*Heterochromatin|Origin Recognition Complex|*DNA Replication|Centromere|Chromatin|Histone|Chromosomal Proteins, Non-Histone|Protein Binding|Telomere|Drosophila|Methylation|LRWD1 protein, human|Microtubule Proteins 22 LSG1 21796981 Wei Sheng Wu Xue Bao 2011 0 0 0 94 1,3-propanediol|*DNA Shuffling|*Propylene Glycols|*Propylene Glycol|Klebsiella pneumoniae|Glycerol|Fermentation|Biotechnology|Bacterial Proteins|*Breeding 26 METRN 22044868 J. Cereb. Blood Flow Metab. 2011 PMC3272610 10.1038/jcbfm.2011.156 11 1 1 47 Rats|Animals|*Neurogenesis|*Corpus Striatum|*Stroke|*Cell Movement|Subventricular Zone|Neurons|Middle Cerebral Artery Occlusion|Neural Stem Cells|Cell Differentiation|Cell Death|Cell Proliferation|Cells, Cultured|Cell Division|Brain 22 METRN 21203507 PLoS ONE 2011 PMC3008721 10.1371/journal.pone.0014391 1 0 0 47 Mice|Humans|Animals|*Mice, Transgenic|T Cells|*Immunologic Deficiency Syndromes|Transgene|Mice, Inbred C57BL|Cell Differentiation|METRN protein, human|Nerve Tissue Proteins|Intercellular Signaling Peptides and Proteins 22 MIDN 21199825 Radiat Prot Dosimetry 2011 10.1093/rpd/ncq525 0 0 0 245 Humans|Cosmic Radiation|Spacecraft|Body Burden|Radiation Monitoring|Whole-Body Counting|Radiation Protection|Radiation Dosage|Astronauts|Relative Biological Effectiveness|Occupational Exposure|*Risk Assessments|Equipment Failure Analysis|Equipment Design 23 MPZL2 21440040 Neurosci. Lett. 2011 10.1016/j.neulet.2011.03.051 8 1 1 144 Animals|Mice|Humans|*Choroid Plexus|*Immunologic Surveillance|*Epithelial Cell|Blood-Brain Barrier|Cell Adhesion Molecules|Intercellular Adhesion Molecule-1|Brain|Immunoglobulin|Biological Transport|CD4-Positive T-Lymphocytes|*Cell Count 22 MTX3 21280197 Pediatr Blood Cancer 2011 10.1002/pbc.22940 6 0 1 133 Child|Humans|*Lymphoma, Large-Cell, Anaplastic|PVDA protocol|Antineoplastic Combined Chemotherapy Protocols|*Neoadjuvant Therapy|Vincristine|Methotrexate|Disease-Free Survival|Vinblastine|Cyclophosphamide|Prednisone|Treatment Outcome|Asparaginase|Daunorubicin 21 ncln 26598162 J Chem Theory Comput 2011 10.1021/ct200408j 0 0 0 65 *Magnetic|Magnetic Resonance Spectroscopy|Quantum Theory|*Physical Phenomena|*Marital Status|Magnetic Phenomena 21 NEUROD4 21965609 Development 2011 10.1242/dev.066563 9 0 1 53 Animals|*Zebrafish|*Neurogenesis|NEUROG1 protein, human|Basic Helix-Loop-Helix Transcription Factors|Nerve Tissue Proteins|Zebrafish Proteins|Embryo, Nonmammalian|Neurons|Gene Expression Regulation, Developmental|Olfactory Bulb|Cell Differentiation|Axons|*Smell|neurod4 protein, zebrafish 59 NHLH1 21854574 BMC Mol. Biol. 2011 PMC3170594 10.1186/1471-2199-12-39 2 0 0 132 Animals|*Marsupial|*Monotremata|Vomeronasal Organ|*Vertebrate|Pheromones|TRPC Cation Channels|Phylogeny|*Genes, Regulator|Signal Transduction 43 NHLH1 21483740 PLoS ONE 2011 PMC3070717 10.1371/journal.pone.0018135 32 6 3 132 *Urinary Bladder Neoplasms|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Cluster Analysis|Gene Expression Regulation, Neoplastic|RNA, Messenger 43 NHLH1 21270357 J. Nutr. 2011 PMC3040910 10.3945/jn.110.127290 25 0 3 132 Humans|Animals|*Physical Activity|Inactivity, Physical|Basic Helix-Loop-Helix Transcription Factors|Obesity 43 OTOP1 21261979 BMC Evol. Biol. 2011 PMC3038909 10.1186/1471-2148-11-23 5 8 0 24 Animals|Mice|*Vertebrate|Evolution, Molecular|Synteny|Phylogeny|*Comparative Genomic Hybridization|Amino Acid Sequence|Multigene Family|Genome|Conserved Sequence|Fishes|Comparative Genomics|Models, Genetic|Sequence Homology, Amino Acid|Sequence Analysis, DNA 23 OTOP1 21236346 Mol. Cell. Neurosci. 2011 PMC3046300 10.1016/j.mcn.2011.01.005 11 1 0 24 Mice|Animals|*Mutation, Missense|*Vestibule, Labyrinth|Otoconia|*Inhibition, Psychological|Membrane Proteins|Mutations|Cell Membrane|*Signal Transduction|Cells, Epithelial|Alleles 23 OTOP1 21205793 Development 2011 10.1242/dev.057752 20 2 1 24 Animals|*Cilia|*Otolithic Membrane|*Biomineralization|*Cues|*Hair Cells, Auditory|Zebrafish|Zebrafish Proteins|Gene Expression Regulation, Developmental|In Situ Hybridization|*Calcification, Physiologic|Cell Differentiation|*Cell Membrane Structures|*Epigenetic|Epigenesis, Genetic 23 oxsr1 22052202 Mol. Cell. Biochem. 2011 10.1007/s11010-011-1127-4 5 4 1 594 Humans|Phosphorylation|Receptor-Mediated Signal Transduction|Carrier Proteins|Phospholipid Transfer Proteins|TNF Receptor|Cell Line|*Tissues, Lymphoid|Epithelial Cells|PLSCR1 protein, human 38 PAGE4 21917134 J Transl Med 2011 PMC3184272 10.1186/1479-5876-9-153 41 0 4 57 Humans|Male|Adult|*Testis|Neoplasm Recurrence, Local|*Prostatectomy|*Prostate Cancer|Prostate-Specific Antigen|*Prostate|Prognosis|*Seminal Vesicles|Biomarkers, Tumor 31 PAGE4 21357425 J. Biol. Chem. 2011 PMC3077599 10.1074/jbc.M110.210765 35 2 3 57 Humans|Male|Mice|Animals|*Prostate|*Testis|*Intrinsically Disordered Proteins|PSCA protein, human|*Antigens, Neoplasm|*Neoplasm Proteins|*GPI-Linked Proteins|Prostatic Neoplasms|Protein Conformation|Cell Line, Tumor|Amino Acid Sequence|Phosphorylation|mRNA|PAGE4 protein, human 31 PARM1 21752155 Neurogastroenterol. Motil. 2011 PMC3173581 10.1111/j.1365-2982.2011.01749.x 11 4 1 49 Humans|*Genetic Predisposition to Disease|*Gastrointestinal Motility|*Functional Gastrointestinal Disorders|Irritable Bowel Syndrome|Gastrointestinal Transit|Phenotype|TNFSF15 protein, human|Tumor Necrosis Factor Ligand Superfamily Member 15|Constipation|Polymorphism, Single Nucleotide|Genotype|Crohn's Disease|*Inflammation 20 PARM1 21362171 BMC Dev. Biol. 2011 PMC3058101 10.1186/1471-213X-11-13 9 6 2 49 Mice|Animals|*Embryonic Stem Cells|pancreatic and duodenal homeobox 1 protein|*Homeodomain Proteins|*Trans-Activators|Endoderm|Cell Differentiation|Pancreas|DNA Microarray|Gene Expression Regulation, Developmental|Cell Line|Cells, Cultured|Gene Expression Profiling|Embryonic Development 20 pax6a 21544580 Hum. Genet. 2011 10.1007/s00439-011-0999-4 10 0 1 0 Humans|Animals|Infant|Pitt-Hopkins syndrome|*Zebrafish|Diffusion Tensor Imaging|*Facies|*Hyperventilation|*Intellectual Disability|*Phenotype|Transcription Factor 4|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Transcription Factors|*Eyes|*Face 32 pax6a 21527633 J. Biol. Chem. 2011 PMC3123087 10.1074/jbc.M111.223834 15 0 3 0 Animals|*Zebrafish|*HMGB1 Protein|Zebrafish Proteins|Gene Expression Regulation, Developmental|Prosencephalon|Nerve Tissue Proteins|Oligonucleotides, Morpholino|Neurons|Signal Transduction|Oligonucleotides, Anti-Sense|Gene Knockdown Techniques|Cell Proliferation|Nervous System|Eyes 32 pax6a 21308976 Birth Defects Res. Part A Clin. Mol. Teratol. 2011 PMC4230012 10.1002/bdra.20766 19 32 0 0 Animals|Female|Pregnancy|*Zebrafish|*Ethanol|*Agrin|Zebrafish Proteins|Embryo, Nonmammalian|Teratogens|Fetal Alcohol Spectrum Disorders|Hedgehog Proteins|Gene Expression Regulation, Developmental|Eye|Tretinoin|Microphthalmia|Brain|Signal Transduction 32 PCDH11Y 21480486 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2011 10.1002/ajmg.b.31186 12 1 1 45 Humans|Male|Animals|Child|In Situ Hybridization, Fluorescence|DNA Copy Number Variations|*Language Delay|Male sterility due to Y-chromosome deletions|Chromosomes, Human, Y|Chromosomes, Human, X|Chromosome Deletion|Hominid|Translocation, Genetic|Language Development|*Syndromes|Intron|Infertility, Male|Sex Chromosome Aberrations|Sex Chromosome Disorders of Sex Development 24 PCDH11Y 21276771 Brain Res. 2011 10.1016/j.brainres.2011.01.054 6 1 0 45 Humans|*Alzheimer Disease|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Gene Frequency|Genotype|Apo E-4|Genetic Predisposition to Disease|Allele|Apolipoproteins E|Asian Continental Ancestry Group|Case-Control Studies|Spain 24 PDZRN3 21546767 Am. J. Nephrol. 2011 PMC3202959 10.1159/000327985 17 0 1 80 Humans|*Genome-Wide Association Study|*African Americans|*Renal Dialysis|*Diabetes Mellitus, Type 2|End Stage Renal Disease|Diabetic Nephropathies|European Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies 26 PGDF 22040922 Eur. J. Pharmacol. 2011 10.1016/j.ejphar.2011.10.011 11 7 2 0 Rats|Animals|*Proto-Oncogene Proteins c-akt|tangeretin|Phosphatidylinositol 3-Kinases|*Citrus|*Smooth Muscle Cells|Platelet-Derived Growth Factor BB|flavone|*Flavones|Muscle, Smooth, Vascular|Proto-Oncogene Proteins c-sis|*Aorta|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Signal Transduction|Phosphorylation|*Flavonoids|Cell Proliferation|Cell Migration 49 PGDF 21774915 Arch. Oral Biol. 2011 10.1016/j.archoralbio.2011.06.020 11 0 1 0 *Platelet-Derived Growth Factor|*Periodontium|*Wound Healing|Periodontal Ligament|Periodontal Diseases|Bone Regeneration|Insulin-Like Growth Factor I|Transforming Growth Factor beta 49 PGDF 21367419 Atherosclerosis 2011 10.1016/j.atherosclerosis.2011.01.050 3 0 0 0 Animals|*Diabetes Mellitus, Experimental|Terminal Complement Complex|*Immunity, Innate|Gene Expression Regulation|Diabetic Angiopathies|RNA, Messenger|Transforming Growth Factor beta|*Complement Activation|*Immunologic Factors|Inflammation 49 pkd1l1 21307098 Development 2011 10.1242/dev.058271 41 1 5 17 Animals|Mice|*Cilia|Body Patterning|Medaka|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|TRPP Cation Channels|Transforming Growth Factor beta 20 pkd1l1 21307093 Development 2011 PMC3042869 10.1242/dev.058149 57 1 5 17 Mice|Animals|Cilia|Body Patterning|TRPP Cation Channels|Gene Expression Regulation, Developmental|Heterotaxy Syndrome 20 PLAC4 22176988 Zhonghua Fu Chan Ke Za Zhi 2011 1 0 0 0 Pregnancy|Humans|Female|*mRNA|*Prenatal Care|*Fetus|Prenatal Diagnosis|Down Syndrome|Alleles|Polymorphism, Single Nucleotide 22 PLAC4 21865357 J. Clin. Endocrinol. Metab. 2011 10.1210/jc.2011-1233 11 0 0 0 Humans|Female|Pregnancy|*Pre-Eclampsia|*mRNA|Placenta|*Biomarkers|*Delivery, Obstetric 22 PLAC4 21303301 Clin. Chem. Lab. Med. 2011 10.1515/CCLM.2011.099 0 0 0 0 Pregnancy|Female|Humans|*Down Syndrome|*Multiplex Polymerase Chain Reaction|*Reverse Transcriptase|*Prenatal Diagnosis|*Trisomy|Amniocentesis|Karyotyping|Chorionic Villus Sampling|Alleles|Fetus|DNA|Polymorphism, Single Nucleotide 22 POU6F1 21955788 BMC Syst Biol 2011 PMC3191490 10.1186/1752-0509-5-152 7 4 0 30 Mice|Animals|*Gene Regulatory Networks|*Neural Stem Cell|Cell Differentiation|Neurons|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Cells, Cultured|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling 34 POU6F1 21317385 J. Immunol. 2011 PMC3155692 10.4049/jimmunol.1003164 11 2 0 30 Mice|Animals|*Chromatin|Histones|Enhancer Elements, Genetic|Receptors, Antigen, T-Cell, alpha-beta|Thymocytes|Heterochromatin|Acetylation 34 PPP1R3A 22106036 Am. J. Med. Genet. A 2011 PMC3319495 10.1002/ajmg.a.34354 28 3 5 909 Humans|Male|Female|*Haploinsufficiency|Comparative Genomic Hybridization|*Mothers|Autism Spectrum Disorder|Apraxia|Language Disorders|Speech Disorders|Chromosome Deletion|Speech|Pedigree|*Phenotype|Forkhead Transcription Factors|Chromosomes, Human|FOXP2 protein, human|PPP1R3A protein, human|Phosphoprotein Phosphatases 40 PPP1R3A 22054094 BMC Biochem. 2011 PMC3240831 10.1186/1471-2091-12-57 9 20 2 909 *Glycogen|*Protein Phosphatase 1|*Myotube|Glycogen Synthase|Muscle, Skeletal|Carrier Proteins|Insulin|Phosphorylation|Intracellular Signaling Peptides and Proteins|Amino Acid Sequence 40 PTPRCAP 21505061 Clin. Cancer Res. 2011 PMC3107873 10.1158/1078-0432.CCR-11-0044 34 5 3 34 Humans|*Head and Neck Cancer|*DNA Methylation|CpG Islands|Head and Neck Squamous Cell Carcinoma|Promoter Regions, Genetic|Carcinoma, Squamous Cell|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Repetitive Regions 48 PYHIN1 21884171 Immunol. Rev. 2011 10.1111/j.1600-065X.2011.01053.x 88 0 5 57 Animals|Receptors, Pattern Recognition|Innate Immune Response|Inflammasomes|Toll-Like Receptors|Nuclear Proteins|Host-Pathogen Interactions|DNA, Viral|Mammals 20 PYHIN1 21804549 Nat. Genet. 2011 PMC3445408 10.1038/ng.888 297 1 15 57 Humans|United States|*Genome-Wide Association Study|*Ethnic Groups|*Asthma|European Continental Ancestry Group|African Americans|Latino|Genetic Predisposition to Disease|African Continental Ancestry Group|Genetic Loci|Polymorphism, Single Nucleotide|*Continental Population Groups|PYHIN1 protein, human|Nuclear Proteins 20 PYHIN1 21701967 Methods Mol. Biol. 2011 10.1007/978-1-61779-139-0_5 0 0 0 57 *Receptors, Immunologic|*Nucleic Acids|Toll-Like Receptors|DEAD Box Protein 58|Immunity, Innate|DEAD-box RNA Helicases|Signal Transduction|Ligands|Immune System 20 RAX2 21679462 BMC Evol. Biol. 2011 PMC3141429 10.1186/1471-2148-11-169 28 0 7 14 Animals|Mice|Humans|*Genes, Homeobox|*Vertebrate|Evolution, Molecular|Phylogeny|Amino Acid Sequence|Gene Expression Regulation|Embryonic Development 25 RAX2 21625000 Genetics 2011 PMC3176097 10.1534/genetics.111.128231 4 1 0 14 *Saccharomyces cerevisiae|*Cell Polarity|Saccharomyces cerevisiae Proteins|*Cytoplasm|Membrane Glycoproteins|Membrane Proteins|Cell Division|Diploid Cells|Green Fluorescent Proteins|Protein-Serine-Threonine Kinases|*B-Lymphocytes|Signal Transduction|Reproduction, Asexual 25 RNF39 21242233 Ann. Rheum. Dis. 2011 10.1136/ard.2010.133561 8 2 0 8 Humans|*Arthritis, Psoriatic|*Major Histocompatibility Complex|Single Nucleotide Polymorphisms|Haplotypes|Genetic Predisposition to Disease|Linkage Disequilibrium|Alleles|Gene Frequency|Locus, Genetic|Case-Control Studies 22 SAMSN1 21859567 Clin Colorectal Cancer 2011 10.1016/j.clcc.2011.03.011 13 0 3 51 *Colitis, Ulcerative|*Reverse Transcriptase Polymerase Chain Reaction|*Colorectal Cancer|*Colonic Neoplasms|Intestinal Mucosa|Polymerase Chain Reaction|Mutation 25 SAMSN1 21296879 J. Biol. Chem. 2011 PMC3075695 10.1074/jbc.M110.155184 9 1 0 51 Humans|Mice|Animals|*Actins|*src Homology Domains|HeLa Cells|*B Cells|*Lymphocyte|rac GTP-Binding Proteins|Signal Transduction|*Phagocytosis|T Cells|rac1 GTP-Binding Protein|Lymphocyte Activation|*Protein Binding|Cytoskeleton|Adaptor Proteins, Vesicular Transport|NCOA3 protein, human|*Nuclear Receptor Coactivator 3|Phosphorylation|*Cell Communication 25 SCAMP2 21295544 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.01.069 1 6 0 316 SLC6A3 protein, human|*Dopamine Plasma Membrane Transport Proteins|Dopamine|Serotonin Plasma Membrane Transport Proteins|Cell Membrane|Serotonin|Nerve Tissue Proteins|Norepinephrine|Membrane Glycoproteins|Neurons|Synapses 26 SCAMP2 21205824 J. Biol. Chem. 2011 PMC3059028 10.1074/jbc.M110.166546 9 3 2 316 *Cell Membrane|Protein Transport|Solute Carrier Family 12, Member 1|Sodium-Potassium-Chloride Symporters|Yeast Two-Hybrid System|Bartters Syndrome|Membrane Proteins|Endosomes|Protein Structure, Tertiary|Carrier Proteins|Exocytosis|Membrane Transport Proteins|Transporter, Sodium-Chloride|Protein Binding|Epithelial Cells|Kidney|cDNA Library 26 SCGB1D2 21385388 Respir. Res. 2011 PMC3063214 10.1186/1465-9921-12-28 8 8 1 18 Humans|*Uteroglobin|*Secretoglobins|*Sinusitis|Nasal Polyps|Rhinitis|*Cytokines|Nasal Mucosa|Epithelial Cells|*Chronic Disease|Cells, Cultured|RNA, Messenger 156 SCRN1 21385630 J Proteomics 2011 10.1016/j.jprot.2011.02.033 12 0 1 65 Humans|*Sarcoma, Synovial|*Proteomics|*Prognosis|Two-Dimensional Difference Gel Electrophoresis|Biomarkers, Tumor|Proteins|Survival Rate 21 SCRN1 21220475 Clin. Cancer Res. 2011 10.1158/1078-0432.CCR-10-2552 8 0 1 65 *Prognosis|*Colon Cancer|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Carcinoma|RNA, Messenger 21 SH3PXD2B 21886807 PLoS ONE 2011 PMC3160312 10.1371/journal.pone.0023653 16 25 2 105 Humans|*Pseudopodia|HeLa Cells|CTTN protein, human|Cortactin|*SH3 Domain|Actins|Cell Movement|Adaptor Proteins, Signal Transducing|Phosphorylation|src-Family Kinases|Cell Surface Extensions|Epidermal Growth Factor|Tks4 protein, human 23 SH3PXD2B 21818352 PLoS ONE 2011 PMC3144925 10.1371/journal.pone.0022622 15 1 2 105 Humans|Mice|Animals|*Otitis Media|Ear, Middle|Eustachian Tube|Disease Models, Animal|Cilia|Inflammation|Hearing Impairment|Goblet Cells 23 SH3PXD2B 21282566 Invest. Ophthalmol. Vis. Sci. 2011 PMC3088558 10.1167/iovs.10-5993 24 0 4 105 Mice|Animals|Child|Early-Onset Glaucoma|*Glaucoma|Anterior segment mesenchymal dysgenesis|*Eye Abnormalities|Intraocular Pressure|Optic Nerve Diseases|Anterior Eye Segment|Retinal Ganglion Cells|*Mutation|Ter Haar syndrome|Craniofacial Abnormalities|Phenotype|Disease Models, Animal|Axons|Developmental Disabilities|Heart Defects, Congenital|Osteochondrodysplasias 23 SHROOM2 21248203 Mol. Biol. Cell 2011 PMC3057704 10.1091/mbc.E10-06-0505 23 28 0 47 Humans|Endothelial Cells|*Morphogenesis|Cell Movement|Neovascularization, Physiologic|Microfilament Proteins|ROCK1 protein, human|rho-Kinase|Endothelium, Vascular|Collagen|Actin|*Muscle Contraction|Cells, Cultured|Cytoskeletal Proteins 26 SKOR1 21925394 Sleep Med. 2011 PMC3514407 10.1016/j.sleep.2011.06.006 12 8 1 30 Humans|*Restless Legs Syndrome|Genome-Wide Association Study|*Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Homeodomain Proteins|Transcription Factors|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Nerve Tissue Proteins|Genotype-Phenotype Association|Neoplasm Proteins|Case-Control Studies|MAP2K5 protein, human|BTBD9 protein, human 24 SKOR1 21641385 Am. J. Pathol. 2011 PMC3124099 10.1016/j.ajpath.2011.02.009 6 0 1 30 *Keloid|*Scleroderma, Localized|*Wound Healing|Fibroblasts|Transforming Growth Factor beta|Collagen Type I|Cell Movement|Extracellular Matrix|Cells, Cultured|Signal Transduction|Fibrosis|Gene Expression Regulation|F-Actin|Cell Proliferation|Cell Adhesion 24 SKOR1 21572129 J. Med. Genet. 2011 PMC3122881 10.1136/jmg.2010.087858 13 0 0 30 Humans|*Restless Legs Syndrome|*Myeloid Ecotropic Viral Integration Site 1 Protein|MAP Kinase Kinase 5|Homeodomain Proteins|Transcription Factors|Genome-Wide Association Study|Case-Control Study|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Neoplasm Proteins|Receptor-Like Protein Tyrosine Phosphatases, Class 2|*End Stage Renal Disease|BTBD9 protein, human 24 SKOR1 21544081 Int J Obes (Lond) 2011 10.1038/ijo.2011.86 31 0 4 30 Humans|Genome-Wide Association Study|Malaysia|*Chinese|*Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Body Mass Index|Polymorphism, Single Nucleotide|Receptor, Melanocortin, Type 4|Genetic Predisposition to Disease|Gene Frequency|Genotype|European Continental Ancestry Group|Diabetes Mellitus, Type 2|Membrane Proteins 24 SLC16A12 21778275 Invest. Ophthalmol. Vis. Sci. 2011 PMC3176021 10.1167/iovs.10-6579 11 0 1 24 *Cataract|*Mutation|Lens, Crystalline|*Plasma Membrane|*Protein Transport|Monocarboxylic Acid Transporters|*Eye Abnormalities|Mutation, Nonsense 24 SLC16A12 21666241 Invest. Ophthalmol. Vis. Sci. 2011 10.1167/iovs.11-7463 14 0 1 24 Humans|*Gene Expression|Dexamethasone|Glucocorticoids|*Cornea|*Fibroblasts|Oligonucleotide Array Sequence Analysis|Trabecular Meshwork|Gene Expression Regulation|Cells, Cultured|Gene Expression Profiling|Eye Proteins|Up-Regulation|RNA, Micro 24 SLC16A12 24213111 Cancers (Basel) 2011 PMC3763396 10.3390/cancers3043773 10 2 1 24 Humans|Male|*Prostate|*Prostate Cancer|DNA Methylation|Epigenetic|Biomarkers, Tumor|Epigenesis, Genetic|Glutathione S-Transferase pi|Genetic Susceptibility 24 SPANXA1 22016418 Hum. Reprod. 2011 10.1093/humrep/der330 14 0 0 37 Male|Adult|Humans|*Seminoma|*Testis|*Testicular Neoplasms|Antigens, Neoplasm|Neoplasm Proteins|Immunohistochemistry|*X Chromosome|Membrane Proteins|Germ Cells 27 srpx 21989018 Mol. Cell Proteomics 2011 PMC3270109 10.1074/mcp.M111.014159 31 0 2 33 Humans|Animals|Mice|*Chondrocytes|*Proteome|Proteomics|*Chondrogenesis|*Extracellular Matrix|Cartilage|Extracellular Matrix Proteins|Cell Differentiation|Collagen|SRPUL protein, human|Neoplasm Proteins|Endochondral Ossification|Protein Processing, Post-Translational|Membrane Proteins|CILP protein, human|Pyrophosphatases 50 STK17B 21956279 Lasers Med Sci 2011 10.1007/s10103-011-0995-x 0 0 2 215 Mice|Rats|Animals|*Mesenchymal Stem Cells|Phosphatidylinositol 3-Kinases|Cell Proliferation|Diode Laser|Bone Marrow Cells|Cell Differentiation|Low-Level Light Therapy|Cells, Cultured|Apoptosis|cDNA Microarray|Upregulation|Real Time PCR 32 STK17B 21489989 J. Biol. Chem. 2011 PMC3103316 10.1074/jbc.M111.218040 11 1 2 215 Humans|Male|Mice|Animals|*Cisplatin|Testicular Germ Cell Tumor|*Testicular Neoplasms|*Tumor Suppressor Protein p53|*Reactive Oxygen Species|NIH 3T3 Cells|*Neoplasms, Germ Cell and Embryonal|Carcinoma, Embryonal|Apoptosis|Antineoplastic Agents|Cell Line, Tumor|Cyclin-Dependent Kinase Inhibitor p21|Gene Expression Regulation, Neoplastic|Embryonal Carcinoma Cell|Cell Survival|Up-Regulation|Transcriptional Activation|Serine Threonine Kinases 32 STOML1 21501885 Eur. J. Cell Biol. 2011 10.1016/j.ejcb.2011.01.018 27 3 1 71 Animals|Membrane Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Nerve Tissue Proteins|Blood Proteins|Amino Acid Sequence|DNA, Complementary 20 SVOP 21953179 Funct. Integr. Genomics 2011 10.1007/s10142-011-0255-y 7 0 1 115 Mice|Animals|*Niacin|Membrane Transport Proteins|*Comparative Genomics|Bacillus subtilis|Lactococcus lactis|Regulons|Bacterial Proteins|Biological Transport|Acinetobacter baumannii|Bacterial Genes|Carrier Proteins|Escherichia coli|Arabidopsis Proteins|*Mammals|Arabidopsis|Thiamin|Kinetics 26 TARBP1 22146072 Biochemistry 2011 PMC3254705 10.1021/bi201570a 12 9 1 41 Humans|*Peptide Nucleic Acids|*RNA, Double-Stranded|*Guanidine|Nucleic Acid Conformation|Base Pairing|purine|Purines|*Guanidines|Calorimetry|Arginine|HIV-1 26 TARBP1 22025453 Mol. Carcinog. 2011 10.1002/mc.20861 38 0 5 41 Humans|*RNA-Induced Silencing Complex|*MicroRNAs|*Double-Stranded RNA-Binding Proteins|AGO2 protein, human|*Argonaute Proteins|*Cancer, Skin|Basal Cell Carcinomas|Actinic Keratoses|Squamous Cell Carcinomas|mRNA|Gene Expression Regulation, Neoplastic|Skin|Quantitative Real Time Polymerase Chain Reaction|Microcomputers|TARBP1 protein, human|Nuclear Proteins|DGCR8 protein, human 26 TBPL1 21711503 Cell Biosci 2011 PMC3142196 10.1186/2045-3701-1-23 21 36 5 1191 Animals|*TATA-Binding Protein-Related Factors|TATA-Binding Protein|TFIIA|Transcription Factors|Transcription, Genetic|Promoter Regions, Genetic|Gene Expression Regulation, Developmental|Amino Acid Sequence|Germ Cells|Embryonic Development|Vertebrates 28 TEX19 22106369 Genome Res. 2011 PMC3290782 10.1101/gr.126417.111 138 0 16 48 Humans|Mice|Animals|5-hydroxymethylcytosine|*5-Methylcytosine|Cytosine|DNA Methylation|Epigenesis, Genetic|Embryonic Stem Cells|Promoter Regions, Genetic|Transcription, Genetic|Cell Lines|Sequence Analysis, DNA|Gene Expression Regulation, Developmental|*Histocompatibility Testing|DNA|Cell Differentiation 20 tiprl 22167190 J. Biol. Chem. 2011 PMC3281656 10.1074/jbc.M111.283341 4 0 2 1859 Animals|Humans|*Protein Phosphatase 2|*Catalytic Domain|HEK293 Cells|Leukocytes, Mononuclear|Holoenzymes|*Splicings, Alternative|Protein O-Methyltransferase|*Isoforms|Phosphorylation|*Biochemical Phenomena|Carboxylic Ester Hydrolases|Models, Molecular|Catalysis 34 TMEM135 22087758 Breast Cancer Res. 2011 PMC3326556 10.1186/bcr3057 16 0 0 40 Humans|Female|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|Receptors, Progesterone|Receptors, Estrogen|Genetic Predisposition to Disease|Case-Control Studies|Alleles|Receptor, Fibroblast Growth Factor, Type 2|*Cancer|Odds Ratio|Genotype|*Epidemiological Study|Risk Factors 20 TTC12 21936764 World J. Biol. Psychiatry 2011 10.3109/15622975.2011.598560 1 0 0 11 Humans|*Tobacco|Smoking|Haplotypes|Tobacco Use Disorder|Alcohol Use Disorders|Linkage Disequilibrium|European Continental Ancestry Group|Alcohol Drinking|Receptors, Dopamine D2|Polymorphism, Single Nucleotide|Protein-Serine-Threonine Kinases|CD56 Antigen|Neural Cell Adhesion Molecules|TTC12 protein, human|Proteins|ANKK1 protein, human 24 TTC12 21663922 J. Neurol. Sci. 2011 PMC3155471 10.1016/j.jns.2011.05.031 13 1 1 11 *Parkinson Disease|DRD2 protein, human|*Receptors, Dopamine D2|Receptors, Dopamine D3|Dopamine Agonists|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide 24 txnl1 21995449 Antioxid. Redox Signal. 2011 PMC3261027 10.1089/ars.2011.4134 7 12 1 480 POU5F1 protein, human|*Octamer Transcription Factor-3|AGO2 protein, human|*Argonaute Proteins|*Cell Nucleus|Cell Differentiation|Stem Cells|Cells, Cultured|Cell Proliferation|Apoptosis|Adipose Tissue 37 txnl1 21543115 Biomaterials 2011 10.1016/j.biomaterials.2011.04.023 14 0 1 480 Humans|*Gold|Proteomics|*Metal Nanoparticles|Two Dimensional Gel Electrophoresis|*Fibroblast|*Lung|Western Blotting|Cell Line|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Down-Regulation|Up-Regulation|*Genomic Instability|Stress Proteins|Oxidative Stress|PDIA3 protein, human|Protein Disulfide-Isomerases|TXNL1 protein, human|Thioredoxins 37 txnl1 21290163 Cell. Mol. Life Sci. 2011 PMC4721677 10.1007/s00018-011-0628-3 6 1 3 480 *Diploidy|*Aneuploid|*Colorectal Cancer|DNA, Neoplasm|Ploidy|Colonic Neoplasms|Carcinomas|HDAC2 protein, human|*Histone Deacetylase 2|Prognosis|Flow Cytometry|Cell Cycle 37 txnl1 21241449 Aging Cell 2011 10.1111/j.1474-9726.2011.00670.x 13 11 0 480 Humans|*Cell Survival|AGO2 protein, human|*Argonaute Proteins|*Stem Cell|*Adipose Tissue|*Selenoprotein|Cell Differentiation|*Cell Nucleus|CASP3 protein, human|Caspase 3|Apoptosis|MAPK, p38|Reactive Oxygen Species|Cell Proliferation|JNK Mitogen-Activated Protein Kinases|WNT5A protein, human|Wnt-5a Protein|Octamer Transcription Factor-3 37 UBAP2L 21204586 J. Proteome Res. 2011 10.1021/pr1008543 17 0 1 157 Humans|*Ubiquitin|*Proteasome Endopeptidase Complex|*Proteomics|*Proteins|Isotope Labeling, Stable|Mass Spectrometry|Amino Acid Sequence|Neurodegenerative Diseases|Protein Binding|Amino Acids|*Cytoplasm|Neuroblastoma|*Inhibition, Psychological|Cell Culture|Ubap2L protein, human|Carrier Proteins 21 VAX2 22183394 Adv. Exp. Med. Biol. 2011 10.1007/978-1-4614-0631-0_87 1 5 0 24 Animals|Mice|*Genes, Homeobox|*Retinal Ganglion Cell|*Cell Differentiation|Homeodomain Proteins|Transcription Factors|Retina|Axons|Gene Expression Regulation, Developmental|Interneurons|EPHB2 protein, human|Receptor, EphB2|neuropilin-2, human|Neuropilin-2|Cell Movement|*Neurogenesis|Vax1 protein, mouse|Neuropeptides 164 VAX2 22128341 RNA 2011 PMC3261733 10.1261/rna.029454.111 43 1 1 24 Mice|Animals|*RNA, Long Noncoding|Cell Differentiation|Progenitor Cells|Retina|Photoreceptor Cells, Vertebrate|*Cell Division|Homeodomain Proteins|Gene Expression Regulation, Developmental|Eye Proteins|Cell Proliferation 164 VAX2 22095910 Hum. Mutat. 2011 PMC3401628 10.1002/humu.21658 0 10 0 24 Humans|Animals|Mice|*Microphthalmos|*Agenesis of Corpus Callosum|Cleft Lip|Cleft Palate|*Phenotype|Homeodomain Proteins|*Mutation|Anophthalmia|Transcription Factors|Homozygote|Mice, Knockout|Exons|Base Sequence|Egypt|VAX2 protein, human|VAX1 protein, human|Vax1 protein, mouse|Neuropeptides 164 VAX2 21896652 Genes Dev. 2011 PMC3175712 10.1101/gad.17594311 4 2 0 24 Animals|*Wnt Signaling Pathway|*Dissent and Disputes|Wnt Proteins|beta Catenin|Xenopus laevis|Xenopus Proteins|Transcription Factor 7-Like 2 Protein|Transcription Factors|Organogenesis|Gene Expression Regulation, Developmental|Genes, Reporter 164 VAX2 21856776 Genes Dev. 2011 PMC3175715 10.1101/gad.17227011 33 3 5 24 Animals|*Wnt Signaling Pathway|Hedgehog Proteins|Xenopus laevis|Xenopus Proteins|Wnt Proteins|Gene Expression Regulation, Developmental|Homeodomain Proteins|Transcription Factors|Nervous System|Shh protein, Xenopus 164 WDFY4 22041458 Psychol Med 2011 PMC3627503 10.1017/S003329171100239X 14 1 0 12 *Pharmacogenomic Testing|*Antidepressive Agents|Citalopram|Depressive Disorder, Major|Genome-Wide Association Study|Pharmacogenetics|Polymorphism, Single Nucleotide|*Drug-Related Side Effects and Adverse Reactions|Genotype|Genetic Variation|Treatment Outcome 20 WFDC1 21936833 Biochem. Soc. Trans. 2011 10.1042/BST0391455 6 1 0 69 Humans|Male|Prostate|WFDC1 protein, human|Proteins|Prostate Cancer|Cell Line|Exons|Tumor Microenvironment|Disulfides|Cell Adhesion|*Homeostasis 42 WFDC1 21936828 Biochem. Soc. Trans. 2011 10.1042/BST0391433 2 0 1 69 Humans|Male|Quality of Life|*Immunotherapy|*Prostate Cancer|Prostatectomy|Prostate|*Proteins|*Immunologic Factors|T-Cells, Regulatory|Tumor Microenvironment 42 WFDC1 21936827 Biochem. Soc. Trans. 2011 10.1042/BST0391427 14 0 2 69 Female|PI3 protein, human|*Elafin|*HIV Infections|SLPI protein, human|*Secretory Leukocyte Protease Inhibitor|Antiproteases|Genitalia, Female|Immunity, Innate|*Social Conditions 42 WFDC1 21936823 Biochem. Soc. Trans. 2011 10.1042/BST0391403 6 0 0 69 Animals|whey acidic proteins|*Phylogeny|*Milk Proteins|Amino Acid Sequence|Sequence Alignment|*Vertebrates|*Invertebrates|Base Sequence|Protein Structure, Tertiary|Penaeidae|Antimicrobial Cationic Peptides|Monotremata|*Disulfides|Protease Inhibitors|Anti-Infective Agents|Gram Positive Bacteria|DNA, Complementary|Cloning, Molecular 42 WFDC1 21936822 Biochem. Soc. Trans. 2011 10.1042/BST0391398 2 0 0 69 Humans|Cattle|Female|Animals|PI3 protein, human|Elafin|Amino Acid Sequence|Sequence Alignment|Protease Inhibitors|Proteins|Protein Structure, Tertiary|Bovine Pancreatic Trypsin Inhibitor|Evolution, Molecular|*Protein Domains 42 WFDC1 21936821 Biochem. Soc. Trans. 2011 10.1042/BST0391393 4 0 0 69 Animals|Mice|Amino Acid Sequence|Sequence Alignment|Proteins|*Protein Domain|Protein Structure, Tertiary|Evolution, Molecular|*Mammals|Sequence Homology, Amino Acid|Phylogeny|Models, Molecular|Disulfides|Amino Acids|Species Specificity 42 WFDC1 21545747 Retrovirology 2011 PMC3108927 10.1186/1742-4690-8-29 0 4 0 69 *HIV-1|*Adhesives|*CD4-Positive T-Lymphocytes|WFDC1 protein, human|*Proteins|ICAM1 protein, human|Intercellular Adhesion Molecule-1|*HIV Seropositivity|Cells, Cultured|*Intercellular Junctions 42 ZBED3 22046406 PLoS ONE 2011 PMC3202571 10.1371/journal.pone.0026911 23 0 2 98 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Japan|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Case-Control Studies|European Continental Ancestry Group|Phenotype 21 ZBED3 21267535 Diabetologia 2011 10.1007/s00125-011-2054-3 15 4 1 98 *Insulin|*Alleles|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|*Insulin, Regular, Human|Oral Glucose Tolerance Test|Insulin Resistance|Insulin-Secreting Cells|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|KCNQ1 Potassium Channel|Genotype|*Risk|Case-Control Studies|Carrier Proteins|Glucose 21 ZC3H12D 22036805 Cell. Signal. 2011 PMC3237786 10.1016/j.cellsig.2011.10.011 0 46 2 498 *Toll-Like Receptor|*Signal Pathways|*Macrophages|Toll-Like Receptor 2|Toll-Like Receptor 4|Macrophage Activation|NF-kappa B|Lipopolysaccharides|Inflammation|Tumor Necrosis Factor-alpha|*Genes, Tumor Suppressor 20 ZC3H14 21734151 Proc. Natl. Acad. Sci. U.S.A. 2011 PMC3145741 10.1073/pnas.1107103108 29 0 2 116 Animals|Humans|*Drosophila|polyadenosine|Drosophila melanogaster|*RNA Binding Protein|*Adenosine|*Polymers|Drosophila Proteins|mRNA|RNA|Nuclear Proteins|Neurons|*Mutation|Conserved Sequence|Central Nervous System|ZC3H14 protein, human 23 zfhx4 21802062 Am. J. Hum. Genet. 2011 PMC3155189 10.1016/j.ajhg.2011.06.012 10 0 0 66 Humans|Adult|*Intellectual Disability|*Chromosome Disorders|*Phenotype|Chromosome Deletion|Facies|Hypotonia|Abnormalities, Multiple|Comparative Genomic Hybridization|Face|Syndrome|*Recognition, Psychology|In Situ Hybridization, Fluorescence|Oligonucleotide Array 26 zfhx4 21357453 J. Anim. Sci. 2011 10.2527/jas.2010-3681 30 0 6 66 Cattle|Female|Animals|*Gene Regulatory Networks|*Polymorphism, Single Nucleotide|Sexual Maturation|*Breeding|Genome-Wide Association Study|Phenotype|Genotype|Transcription Factors 26 ZNF644 21695231 PLoS Genet. 2011 PMC3111487 10.1371/journal.pgen.1002084 61 0 9 140 Humans|*Exome|*Mutations|*Myopia|*Whole Exome Sequencing|Exons|Transcription Factor|Genetic Predisposition to Disease|Pedigree|Base Sequence|Eye|Asian Continental Ancestry Group|Phenotype|ZNF644 protein, human 20 ABI3BP 21041247 Am J Psychiatry 2010 PMC3795390 10.1176/appi.ajp.2010.10040541 47 0 2 65 Humans|*Genome-Wide Association Study|*Suicide, Attempted|Genetic Predisposition to Disease|Bipolar Disorder|Polymorphism, Single Nucleotide|Depressive Disorder, Major|Genotype 27 ADAM29 20664990 Oncol. Rep. 2010 10.3892/or_00000924 8 0 2 13 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Natural Killer T-Cells|CD56 Antigen|Killer Cells, Natural|ZAP70 protein, human|ZAP-70 Protein-Tyrosine Kinase|Immunophenotyping|Cytotoxicity, Immunologic|CD3 Complex|Flow Cytometry|*Cytokines|Receptors, IgG 31 ADAM7 20945367 J. Cell. Physiol. 2010 10.1002/jcp.22444 5 1 0 20 Male|Mice|Animals|*Membrane Proteins|*Calnexin|*Sperm|Epididymis|Sperm Capacitation|molecular chaperone GRP78|*Heat-Shock Proteins|*Molecular Chaperones|ADAM Proteins|Testis|Fertilization|Cell Membrane|Membrane Microdomains|Proteomics|Adam7 protein, mouse|Adam3 protein, mouse|Membrane Glycoproteins 24 ADAM7 20630080 BMC Evol. Biol. 2010 PMC3055250 10.1186/1471-2148-10-211 11 5 2 20 Animals|*Xenopus laevis|Genome-Wide Association Study|*Genome|Sequence Alignment|Xenopus Proteins|Base Sequence|Evolution, Molecular|Phylogeny|Amino Acid Sequence|Expressed Sequence Tag|Conserved Sequence|Chromosome Mapping|Sequence Homology, Amino Acid|Sequence Analysis, DNA 24 ADAM7 20140612 Eur. J. Nucl. Med. Mol. Imaging 2010 10.1007/s00259-009-1379-3 18 0 1 20 Humans|Animals|Mice|Female|*Adenovirus|*Genes, Reporter|*Peritoneal Neoplasms|Oncolytic Viruses|Oncolytic Virotherapy|*Adenoviridae Infections|sodium-iodide symporter|*Symporters|Cell Line, Tumor|Xenograft Model Antitumor Assays|Ovarian Neoplasms|Iodine Radioisotopes|Injections, Intraperitoneal 24 AGAP1 20699438 Blood 2010 PMC3321747 10.1182/blood-2009-08-239681 158 0 14 202 Child|Humans|*DNA Copy Number Variations|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|CRLF2 protein, human|Receptors, Cytokine|*Gene Expression Profiling|Ikaros Transcription Factor|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|*Microarray Analysis|Kaplan-Meier Estimate|Clustering|Chromosomal Translocations|Relapse|Cohort Studies|Gene Deletion|CLEC12A protein, human|Receptors, Mitogen|Lectins, C-Type|GPR110 protein, human 25 AGAP1 20664521 EMBO J. 2010 PMC2924642 10.1038/emboj.2010.154 40 1 3 202 Animals|*M5 Muscarinic Receptor|*Dopamine|Corpus Striatum|Receptors, Muscarinic Acetylcholine|Mesencephalon|Dopaminergic Neurons|Neostriatum|alterporriol B|*Anthraquinones 25 ANKRD17 20593048 J Gastrointestin Liver Dis 2010 7 0 0 122 *Colorectal Cancer|*Mismatch Repair|Adenocarcinoma|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Intestinal Mucosa|RNA, Messenger|*Gene Expression|Europe 24 BLID 21031016 Mol. Vis. 2010 PMC2956664 7 0 0 49 Humans|*Asian Continental Ancestry Group|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|*Myopia|Genetic Association Studies|Linkage Disequilibrium|Haplotypes|Genome-Wide Association Study|Case-Control Studies|BLID protein, human|Apoptosis Regulatory Proteins 187 C2CD4B 21103350 PLoS ONE 2010 PMC2984505 10.1371/journal.pone.0015542 35 8 3 16 Humans|Genome-Wide Association Study|*Transcription Factor 7-Like 2 Protein|*Chinese|*Transcription Factors|Genetic Predisposition to Disease|Blood Glucose|Polymorphism, Single Nucleotide|Insulin|IGF1 protein, human|*IGF-1|Genetic Loci|Fasting|Diabetes Mellitus, Type 2|Glucose|Genotype|Phenotype|TCF7L2 protein, human|CRY2 protein, human 24 C2CD4B 20818381 Nat. Genet. 2010 10.1038/ng.660 108 0 14 16 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Japan|SNPs|Asian|Genetic Predisposition to Disease|Case-Control Studies|Genotype|UBE2E2 protein, human|Ubiquitin-Conjugating Enzymes 24 C2CD4B 20419449 Diabetologia 2010 10.1007/s00125-010-1753-5 43 2 2 16 Middle Aged|Humans|Aged|Genome-Wide Association Study|Denmark|OGTT|Insulin|Blood Glucose|Genetic Loci|Fasting|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Diabetes Mellitus, Type 2|Alleles|Glucose|Genotype|Insulin Sensitivity|GLIS3 protein, human|Transcription Factors|ADRA2A protein, human|Receptors, Adrenergic, alpha-2 24 CDC42EP4 20385374 Biol. Psychiatry 2010 PMC2900524 10.1016/j.biopsych.2010.02.016 45 7 2 127 *Dendritic Spines|*Schizophrenia|Antipsychotic Agents|Dorsolateral Prefrontal Cortex|Pyramidal Neurons|cdc42 GTP-Binding Protein|mRNA|Dendrites|Signal Transduction 20 CDH19 20358601 Am. J. Med. Genet. A 2010 PMC2922899 10.1002/ajmg.a.33341 11 6 0 36 Humans|Male|Mice|Animals|*Microphthalmos|In Situ Hybridization, Fluorescence|*Maternal Inheritance|Hernia, Anterior Diaphragmatic|*Hernias, Diaphragmatic, Congenital|*Chromosome Deletion|*Hernia, Hiatal|Diaphragm|Transcription Factors|Karyotyping|Haploinsufficiency|*Chromosome Structures 25 CDH22 20723620 Gene Expr. Patterns 2010 10.1016/j.gep.2010.08.002 10 0 0 30 Animals|Mice|*Cadherins|In Situ Hybridization|Gene Expression Regulation, Developmental|mRNA|Cerebellum|Hippocampus|Neocortex|Neurons|Amino Acid Sequence|Sequence Alignment|Cdh22 protein, mouse 26 CDKL2 21124932 PLoS ONE 2010 PMC2989917 10.1371/journal.pone.0014078 13 2 1 100 Genome-Wide Association Study|Case-Control Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Receptors, Progesterone|Estrogen Receptor alpha|Genotype|Gene Frequency|Odds Ratio|*Cell Transformation, Neoplastic|Risk|*Germ Line|Mutations|Poland 20 CDKL2 20428496 Front Behav Neurosci 2010 PMC2859807 10.3389/fnbeh.2010.00017 7 6 0 100 Humans|Animals|Mice|*Spatial Learning|*Cognitive Function|*Cyclin-Dependent Kinases|Hippocampus|Amygdala|Avoidance Learning|Maze Learning|CDKL2 protein, human|Calcium-Calmodulin-Dependent Protein Kinases|Fear|Neurons|Protein-Serine-Threonine Kinases|Brain|Behavior, Animal|Thalamus|Cyclins 20 CEND1 20153830 Mol. Cell. Neurosci. 2010 10.1016/j.mcn.2010.01.011 9 0 0 30 Mice|Animals|*Cerebellum|*Neurons|reelin protein|Nerve Tissue Proteins|Cell Differentiation|Purkinje Cells|Neurogenesis|Cell Cycle|Mice, Knockout|Membrane Proteins|Cell Migration|Cell Proliferation|BDNF protein, human|Brain-Derived Neurotrophic Factor|Nervous System|Gene Expression Regulation, Developmental|CCND1 protein, human|Cyclin D1 26 CES1P1 20931200 Mamm. Genome 2010 PMC3127206 10.1007/s00335-010-9284-4 48 0 4 5 Rats|Mice|Animals|Humans|*Carboxylesterase|*Mammals|Amino Acid Sequence|Multigene Family|Pseudogenes|Gene Expression Regulation, Enzymologic 20 CES1P1 20195289 Pharmacogenomics J. 2010 10.1038/tpj.2010.5 12 0 2 5 Humans|*Carboxylesterase|*Isoniazid|Pilot Projects|Carboxylesterases|Genotype|Single Nucleotide Polymorphisms|Linkage Disequilibrium|*DNA Mutational Analysis|Liver|Exons|Chemical and Drug Induced Liver Injury|*Adverse Drug Reaction|CES2 protein, human 20 CLMN 21086988 Inorg Chem 2010 10.1021/ic101687m 4 0 0 48 titanium dioxide|*Titanium|*Transition Elements|Metals|*Oxides|Crystallography, X-Ray|Models, Molecular|*Prostheses and Implants 29 CLMN 20339536 PLoS ONE 2010 PMC2842298 10.1371/journal.pone.0009763 98 9 2 48 Humans|*Hydroxymethylglutaryl-CoA Reductase Inhibitors|*Genome-Wide Association Study|LDL Cholesterol|Heptanoic Acids|Atorvastatin|Simvastatin|Pravastatin|Anticholesteremic Agents|Hypercholesterolemia|Fluorobenzenes|Pyrroles|Rosuvastatin Calcium|Pyrimidines|*Lipids|Triglycerides|Sulfonamides|Single Nucleotide Polymorphisms 29 CMPK2 21130742 Biochem. Biophys. Res. Commun. 2010 10.1016/j.bbrc.2010.11.136 5 1 0 29 Humans|Mice|Animals|DDX58 protein, human|DEAD Box Protein 58|*Epithelial Cells|Toll-Like Receptor 3|Interferon-Induced Helicase, IFIH1|Poly I-C|DEAD-box RNA Helicases|RNA, Double-Stranded|Up-Regulation|Cytokines|mRNA|Cells, Cultured|Epithelium|Signal Transduction|CCL5 protein, human|Chemokine CCL5|IPS-1 protein, mouse|Adaptor Proteins, Signal Transducing 21 CMPK2 20136355 Pharmacogenomics 2010 10.2217/pgs.09.152 13 0 0 29 Humans|*Beta-IFN-1b|Interferon-beta|Multiple Sclerosis, Relapsing-Remitting|Oligonucleotide Array Sequence Analysis|*Recurrence|Gene Expression Profiling|Gene Expression|Multiple Sclerosis|Leukocytes, Mononuclear|*Genetic Profile|RNA 21 COX6A2 20566336 Toxicol. Lett. 2010 10.1016/j.toxlet.2010.06.001 5 3 1 26 Rats|Humans|Animals|AHR protein, human|*Aryl Hydrocarbon Receptor|pentabromodiphenyl ether|*Halogenated Diphenyl Ethers|CYP1A1 protein, human|CYP1A1|*Basic Helix-Loop-Helix Transcription Factors|Polybrominated Biphenyls|*Gene Expression|Oligonucleotide Array Sequence Analysis|Zebrafish|Gene Expression Profiling|Cell Line, Tumor|Signal Transduction|Gene Expression Regulation|SIM2 protein, human|Sim2 protein, rat 24 COX6A2 20307258 Biochem. J. 2010 10.1042/BJ20091714 35 7 2 26 Animals|Humans|*Electron Transport Complex IV|*Oxidase|*Carrier Proteins|*Cell Nucleus|Mitochondrial Proteins|Mitochondria|*Cytochromes c|Respiratory Complex I|Protein Subunits|Membrane Proteins|Cell Lines|RNA Interference 24 COX6A2 20211233 J Ethnopharmacol 2010 10.1016/j.jep.2010.02.027 3 4 0 26 Mice|Animals|*Berberine|*Drugs, Chinese Herbal|*Microglia|Coptis|Berberine Alkaloids|Rhizome|Chromatography, High Pressure Liquid 24 CPA6 20885977 PLoS ONE 2010 PMC2945764 10.1371/journal.pone.0012967 10 1 2 44 Animals|*Zebrafish|*Neural Pathfinding|carboxypeptidase A6, zebrafish|Zebrafish Proteins|Carboxypeptidases A|*Skull|Duane Syndrome|Somites|Mutations|Models, Molecular|Cranial Nerve 24 CPA6 20855895 J. Biol. Chem. 2010 PMC2992257 10.1074/jbc.M110.158626 13 1 1 44 Humans|*Substrate Specificity|HEK293 Cells|carboxypeptidase A6, human|*Carboxypeptidases A|Duane Syndrome|Amino Acid Sequence|Carboxypeptidases|Peptides|Kinetics|Models, Molecular 24 CRTAC1 20382749 Am. J. Physiol. Lung Cell Mol. Physiol. 2010 PMC2904098 10.1152/ajplung.00427.2009 24 0 1 35 Humans|*Gene Expression Regulation|*Cultured Cells|*Lung|*Cell Line|Dexamethasone|Pulmonary Surfactants|Glucocorticoids|Cell Differentiation|Fetus|Alveolar Epithelial Cells|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Cyclic AMP|RNA, Messenger|DUOX1|CRTAC1 protein, human|Calcium-Binding Proteins 27 CRTAC1 20171266 Gene 2010 10.1016/j.gene.2010.02.003 1 1 0 35 Animals|Humans|Male|Phylogeny|Amino Acid Sequence|*Gland, Pituitary|Sparus auratus|Base Sequence|Sequence Alignment|Fish Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Gene Expression|Cloning, Molecular|DNA, Complementary|Vertebrates|Sequence Homology, Amino Acid|Genomes|*Cyanobacteria|CRTAC1 protein, human|Calcium-Binding Proteins 27 CRYBB3 20450675 Zhonghua Yan Ke Za Zhi 2010 3 0 0 14 Child|Humans|Animals|*Cataract|gamma-Crystallins|DNA Mutational Analysis|Pedigree|Mutation|CRYBB1 protein, human|beta-Crystallin B Chain|CRYBA1 protein, human|beta-Crystallin A Chain|CRYBB3 protein, human|CRYGD protein, human 36 CSMD2 20360844 PLoS ONE 2010 PMC2845611 10.1371/journal.pone.0009879 21 0 4 9 20 CSMD2 20171287 Neuroimage 2010 PMC2900429 10.1016/j.neuroimage.2010.02.032 124 1 4 9 Humans|Male|Aged|Aged, 80 and over|*Genome-Wide Association Study|Alzheimer Disease|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Brain|Neuroimaging|Image Interpretation, Computer-Assisted|Magnetic Resonance Imaging|Cognitive Impairment, Mild|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins 20 CST8 21051588 J. Androl. 2010 PMC3215337 10.2164/jandrol.110.010694 9 3 0 190 Male|Mice|Animals|*Epididymis|*Testis|*Spermatogenesis|*Cystatins|Sperm|Spermatids|Cst8 protein, mouse 31 CST8 20811015 Biol. Reprod. 2010 PMC3012566 10.1095/biolreprod.110.084855 11 0 1 190 Male|Female|Mice|Animals|*Epididymis|*Spermatogenesis|*Spermatozoa|*Cystatins|Sperm Maturation|Acrosome Reaction|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|3-Isobutyl-1-methylxanthine|cAMP Protein Kinase|Fertility|Cst8 protein, mouse 31 CST8 20565543 Evol. Dev. 2010 10.1111/j.1525-142X.2010.00418.x 4 0 0 190 Male|Animals|Humans|Female|Pregnancy|Phylogeny|*Genes, vif|*Reproduction|*Type 2 Cystatins|Testis|Amino Acid Sequence|In Situ Hybridization|Male Reproductive System|DNA, Complementary|RNA, Messenger|Promoter Regions, Genetic 31 CYP4X1 20716162 Histopathology 2010 10.1111/j.1365-2559.2010.03606.x 37 0 2 8 *Cytochrome P450|Biomarkers, Tumor|Cytochrome P-450 CYP1B1|Cytochrome P-450 CYP3A 26 CYP4X1 20133390 Pharmacol. Rev. 2010 PMC2835397 10.1124/pr.109.001081 30 0 1 8 Humans|anandamide|*Endocannabinoids|*Arachidonic Acids|*Polyunsaturated Alkamides|Cannabinoid Receptor Modulators|fatty-acid amide hydrolase|Amidohydrolases|Receptors, Cannabinoid|cytochrome P-450 4X1|*Cytochrome P-450 Monooxygenase|Cannabinoids|*Oxidation-Reduction|CYP2D6|Pain 26 DACH2 20160164 Blood 2010 10.1182/blood-2009-07-234229 24 0 1 37 Adult|Child|Humans|Comparative Genomic Hybridization|*Leukemia, B-Cell|PAX5 Transcription Factor|*Acute Lymphoblastic Leukemia|Translocation, Genetic|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Oncogene Proteins, Fusion|In Situ Hybridization, Fluorescence|*Acute Disease|Karyotyping|Gene Deletion|PAX5 protein, human 36 DAZ3 20873591 Zhonghua Nan Ke Xue 2010 2 0 0 1 Humans|Male|*Spermatogenesis|Deleted in Azoospermia 1 Protein|Oligospermia|Chromosomes, Human, Y|Infertility, Male|Chromosome Deletion|Gene Deletion 20 DAZ3 20823911 Eur. J. Hum. Genet. 2010 PMC3039514 10.1038/ejhg.2010.151 13 0 2 1 Humans|Male|Case-Control Studies|*Prevalence|Oligospermia|Arrest of spermatogenesis|Azoospermia|Deleted in Azoospermia 1 Protein|Infertility, Male|Chromosomes, Human, Y|Spermatogenesis|Chromosome Deletion|Genetic Loci|Gene Deletion|Asian Continental Ancestry Group|Sertoli Cell-Only Syndrome 20 DDX10 21156227 Cancer Genet. Cytogenet. 2010 10.1016/j.cancergencyto.2010.09.002 6 0 1 68 *Leukemia, Lymphocytic, Chronic, B-Cell|Cell Cycle Proteins|Tumor Suppressor Proteins|DNA-Binding Proteins|Ataxia Telangiectasia Mutated Proteins|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Chromosome Deletion|Chromosome Aberrations|miRNAs|Gene Deletion|In Situ Hybridization, Fluorescence|Downregulation|Single Nucleotide Polymorphism|Gene Dosage 29 DDX10 20941364 PLoS ONE 2010 PMC2948006 10.1371/journal.pone.0012791 0 3 1 68 Humans|DDX10 protein, human|DEAD-box RNA Helicases|Binding Site|Protein Structure, Tertiary|Crystallography, X-Ray|Amino Acid Sequence|RNA|Models, Molecular|Conserved Sequence|Adenosine Triphosphate|Protein Domains|DDX18 protein, human 29 DDX10 20339440 Leukemia 2010 PMC2868946 10.1038/leu.2010.42 0 17 1 68 Humans|nuclear pore complex protein 98|Nuclear Pore Complex Proteins|*Oncogene|DDX10 protein, human|*DEAD-box RNA Helicases|*DNA Helicases|Homeodomain Proteins|Oncogene Proteins, Fusion|Leukemia, Myeloid, Acute|Hox Genes|Transcription, Genetic|Cell Nucleus|Cell Transformation, Neoplastic|SOX4 protein, human|SOXC Transcription Factors 29 DDX10 20233715 J. Biol. Chem. 2010 PMC2871492 10.1074/jbc.M109.048785 20 10 2 68 Humans|nuclear pore complex protein 98|*Active Transport, Cell Nucleus|Nucleoporin|NUP214 protein, human|Karyopherins|Cell Nucleus|Receptors, Cytoplasmic and Nuclear|Oncogene Proteins, Fusion|RELA protein, human|Transcription Factor RelA|DDX10 protein, human|DEAD-box RNA Helicases|NF-kappa B|Protein Transport 29 DLEU7 20863894 Semin. Cancer Biol. 2010 PMC2997849 10.1016/j.semcancer.2010.09.003 25 46 0 16 Mice|Animals|*Leukemia, Lymphocytic, Chronic, B-Cell|MicroRNAs|B-Lymphocytes|Proto-Oncogene Proteins|ZAP70 protein, human|ZAP-70 Protein-Tyrosine Kinase|Disease Models, Animal 23 DLEU7 20495622 Epigenomics 2010 PMC2872502 10.2217/epi.09.10 19 9 0 16 *DNA Methylation|*Leukemia, Lymphocytic, Chronic, B-Cell|CpG Islands|Epigenesis, Genetic|Gene Expression Regulation, Leukemic|Promoter Regions, Genetic|Epigenetic|Gene Expression Regulation, Neoplastic 23 DLEU7 20400458 Hum. Mol. Genet. 2010 PMC2883343 10.1093/hmg/ddq154 53 0 1 16 Humans|*Genome-Wide Association Study|Nigeria|African Americans|European Continental Ancestry Group|Single Nucleotide Polymorphisms|*Phenotype|Genotype|*Anthropometry|Chromosome Mapping|Body Mass Index 23 DLEU7 20071661 Blood 2010 PMC2869560 10.1182/blood-2009-10-249367 25 1 2 16 Humans|Mice|Animals|*Leukemia, Lymphocytic, Chronic, B-Cell|Genes, Tumor Suppressor|13q deletion syndrome|*Chromosome Deletion|Tumor Suppressor Proteins|*Chromosomes, Human, Pair 13|Nuclear Factor-Kappab|MicroRNAs|*Chromosome Disorders|Transgenic Mouse 23 DOC2A 20503337 Am. J. Med. Genet. A 2010 PMC3160635 10.1002/ajmg.a.33415 24 1 1 31 Child|Humans|*Seizure Disorder|*Seizure|Autism|Mental Retardation|Chromosome Duplication|Chromosome Deletion|Microcephaly|Phenotypes|Developmental Disabilities|DNA Copy Number Variations|*Chromosome Structures|SEZ6L2 protein, human|Membrane Proteins 42 DOC2A 20489179 Proc. Natl. Acad. Sci. U.S.A. 2010 PMC2890845 10.1073/pnas.1000274107 83 0 6 31 Adult|Humans|Adolescent|*DNA Copy Number Variations|*Schizophrenia|Genetic Susceptibility|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genotype|*Synaptic Transmission|Cohort Studies|RiT2 protein, human|Monomeric GTP-Binding Proteins 42 DOC2A 20403080 J. Neurochem. 2010 10.1111/j.1471-4159.2010.06739.x 12 1 0 31 Rats|Humans|Mice|Animals|*PC12 Cells|Exocytosis|Secretory Vesicles|Synaptotagmin I|Calcium-Binding Proteins|Nerve Tissue Proteins|Plasma Membrane|Binding Site|Protein Structure, Tertiary|Protein Binding|Membrane Glycoproteins|Amino Acid Sequence|Calcium|Isoforms|Syntaxin-1A|Phospholipids 42 DRAM2 20527021 J. Pathol. 2010 10.1002/path.2717 9 1 0 31 *Stomach Neoplasms|*Escherichia coli|*Membrane Proteins|Gene Expression Regulation, Neoplastic|*Intestines|Biomarkers, Tumor|*Phenotype|Mucin|Ampicillin|Cell Line, Tumor 21 EIF1AY 20823116 Hum. Reprod. 2010 PMC2955557 10.1093/humrep/deq242 6 0 0 31 Pregnancy|Male|Female|Humans|Child|Cattle|Animals|*Live Birth|H-Y antibody|*Recurrent Miscarriage|Isoantibodies|H-Y Antigen|Pregnancy Outcome|Histocompatibility Antigens Class II|IgY|Birth 26 ENOSF1 20458436 Thromb. Haemost. 2010 10.1160/TH09-11-0748 10 0 2 12 Humans|*Brain Ischemia|*Stroke|Genetic Susceptibility|Haplotypes|SNPs|Methylenetetrahydrofolate reductase deficiency|Methylenetetrahydrofolate Reductase (NADPH2)|Gene Frequency|Genotype|Ferredoxin-NADP Reductase|Risk Factors|Odds Ratio|Case-Control Studies|Homocystinuria|Muscle Spasticity|Psychotic Disorders|Methionine|PON1 protein, human 23 EPB41L4B 21047774 Mol. Cancer Res. 2010 10.1158/1541-7786.MCR-10-0186 6 2 1 90 Humans|Male|*Matrix Metalloproteinase 9|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|mRNA|hammerhead ribozyme|RNA, Catalytic|Prostate Cancer|Cohort Studies 23 EPB41L4B 20868368 Biochem. J. 2010 PMC4739517 10.1042/BJ20100774 11 17 0 90 Humans|*FERM Domains|*Interferon|JAK1 protein, human|Janus Kinase 1|*Transductions, Signal|Janus Kinase 2|STAT1 protein, human|STAT1 Transcription Factor|Phosphorylation|Receptors, Cytokine|*Antiviral Agents|Mutation|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Cell Line, Tumor 23 EPB41L4B 20860828 BMC Cancer 2010 PMC2955608 10.1186/1471-2407-10-505 16 6 2 90 Humans|Male|*Prostate Cancer|Transcriptional Regulator ERG|*Oncogenes|*Cytoskeleton|*Oncogenesis|Gene Expression Regulation, Neoplastic|DNA Methylation|Trans-Activators|*Genes, Regulator|Cell Line, Tumor|Adenocarcinoma|Cytoskeletal Proteins|Gene Expression Profiling|*Gene Expression|*Extracellular Matrix|ERG protein, human 23 ERI3 20225551 Rev Prat 2010 1 0 0 23 Male|Humans|Incidence|Registries|Prostate Cancer|Screening|Record|Rare Diseases|France|Data Management 25 ERI3 20059780 Int J Technol Assess Health Care 2010 10.1017/S0266462309990808 6 0 1 23 *Cost-Benefit Analysis|*Early Detection of Cancer|Guaiac|Occult Blood|*Colorectal Neoplasms|Colonoscopy|Immunochemistry|Screening|Sensitivity and Specificity|Indicators and Reagents|*Diagnostic Tests, Routine|France 25 ETV3 20462409 BMC Cancer 2010 PMC2885361 10.1186/1471-2407-10-195 3 3 0 1655 Humans|Loss of Heterozygosity|Lymphoma, Follicular|Oligonucleotide Array Sequence Analysis|*Heterozygote|Lymphoma, Large B-Cell, Diffuse|Genes, Tumor Suppressor|Single Nucleotide Polymorphisms|*Cohort Studies|Gene Dosage|Microsatellite Repeats 23 EVX2 21098566 Development 2010 10.1242/dev.058701 4 1 0 14 Mice|Animals|*Drosophila|Transcription Factors|Homeodomain Proteins|Drosophila Proteins|Hox Genes|Binding Sites|Gene Expression Regulation, Developmental|Base Sequence|Conserved Sequence|Promoter Regions, Genetic|Morphogenesis|Vertebrate 33 EVX2 21068127 J. Med. Genet. 2010 10.1136/jmg.2010.079491 4 0 0 14 Humans|*Chromosome Disorders|Split-Hand-Foot Malformation 5|Limb Deformities, Congenital|Chromosome Deletion|Ectrodactyly|Hand Deformities, Congenital|Abnormalities, Multiple|Comparative Genomic Hybridization|Intellectual Disability|Phenotype|Transcription Factors|In Situ Hybridization, Fluorescence|Syndrome|Haploinsufficiency 33 EVX2 20648051 Eur. J. Hum. Genet. 2010 PMC3002849 10.1038/ejhg.2010.116 8 0 0 14 Animals|Mice|Kantaputra Gorlin syndrome|*Ulna|*Radius|*Bone Diseases, Developmental|*Fibula|*Foot Deformities|Homeodomain Proteins|Phenotype|Pedigree|Multigene Family|In Situ Hybridization, Fluorescence|*Chromosome|Thailand 33 FAIM3 20884121 Vet. Parasitol. 2010 10.1016/j.vetpar.2010.08.037 8 1 2 72 Cattle|Animals|*Ostertagia|*Complement Factor B|Ostertagiasis|Abomasum|Cattle Diseases|Antibodies, Helminth|Cytokines|Mucosa|Gene Expression Regulation|Transcriptome Analysis|Real-Time Polymerase Chain Reaction|mRNA|Complement Activation 23 FAIM3 20042454 Int. Immunol. 2010 10.1093/intimm/dxp121 40 1 3 72 Humans|*Fc Receptors|HeLa Cells|B Cells|Immunoglobulin M|Lymphocyte Activation|Carrier Proteins|Membrane Proteins 23 FASTKD2 20869947 Biochem. Biophys. Res. Commun. 2010 PMC2963690 10.1016/j.bbrc.2010.09.075 23 13 2 49 Humans|Mice|Animals|*Protein, Mitochondrial|FASTK protein, human|Protein-Serine-Threonine Kinases|Mitochondria|RNA Interference|Encephalomyopathy, Mitochondrial|HeLa Cells|Protein Biosynthesis|Energy Metabolism|Oxygen Consumption|FASTKD2 protein, human|FASTKD3 protein, human 22 FASTKD2 20407090 Circ Cardiovasc Genet 2010 PMC3045864 10.1161/CIRCGENETICS.109.925644 11 2 0 49 *Heart Rate|*Exercise|Genetic Linkage|Quantitative Trait Locus|Physical Endurance|Genotype|Polymorphism, Single Nucleotide 22 Fcrla 21149418 Int. Immunol. 2010 PMC3003704 10.1093/intimm/dxq456 14 1 1 38 Humans|B Cells|Immunoglobulin M|*Endoplasmic Reticulum|Fc Receptor|Immunoglobulin G|lysyl-aspartyl-glutamyl-leucine|Protein Sorting Signals|Ligands|Immunoglobulin A|FCRLA protein, human|Receptors, Immunologic 27 Fcrla 20869045 Cell. Immunol. 2010 PMC2995445 10.1016/j.cellimm.2010.08.007 5 1 2 38 Mice|Animals|FCGR2B protein, human|*Receptors, IgG|B Cells|Mice, Inbred Strains|Promoter Regions, Genetic|Allele|Responses, Antibody|Lymphocyte Activation|Polymorphism, Genetic|Upregulation|*Phenotype 27 Fcrla 20668221 J. Immunol. 2010 10.4049/jimmunol.1001428 18 0 2 38 Humans|Mice|Animals|*Fc Receptor|B Cells|Receptors, Antigen, B-Cell|Immunoglobulin M|*Antigen|gamma RI, Fc|Germinal Center|Immunoglobulin G|Lymphocyte 27 FERD3L 20849957 Mol. Cell. Neurosci. 2010 10.1016/j.mcn.2010.09.002 7 1 0 19 Mice|Animals|Hedgehog Proteins|Transcription Factor|Neural Tube|*Promoter Regions, Genetic|Homeodomain Proteins|Hepatocyte Nuclear Factor 3-beta|Gene Expression Regulation, Developmental|Cell Differentiation|Nerve Tissue Proteins|Binding Sites|Spinal Cord|Central Nervous System|Ferd3l protein, mouse 21 FERD3L 20460368 Development 2010 10.1242/dev.042572 8 3 0 19 Mice|Animals|*Mesencephalon|*Neurogenesis|Transcription Factor|Cell Differentiation|Neural Tube|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Hepatocyte Nuclear Factor 3-beta|Nerve Tissue Proteins|*Transcription Factors, General|Stem Cells|Spinal Cord|Dopaminergic Neurons|Mice, Knockout|Dopamine 21 FKBP11 20838829 J. Bone Miner. Metab. 2010 10.1007/s00774-010-0221-0 39 0 0 61 Female|Pregnancy|Mice|Animals|*Interferon|*Osteoblast|IFITM5 protein, mouse|*Membrane Protein|Bone Formation|Bone|*Antiviral Agents|Bone Development|FKBP|Cell Differentiation|Phenotypes|Homozygote|Heterozygote 21 FKBP11 20230691 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010 0 0 0 61 Humans|*Antibodies|Cloning, Molecular|Genetic Vectors|Gene Expression|Polymerase Chain Reaction|Escherichia coli 21 FLVCR2 20823265 Mol. Cell. Biol. 2010 PMC2976379 10.1128/MCB.00690-10 37 1 1 41 Humans|Animals|Pregnancy|Female|Cats|*Haem|Encephaloclastic Proliferative Vasculopathy|*Hydranencephaly|Receptors, Virus|Feline Leukemia Virus|Membrane Transport Proteins|Amino Acid Sequence|Phenotypes|Mutations|Biological Transport|Brain|Vascular Diseases|FLVCR1 protein, human|FLVCR2 protein, human 22 FLVCR2 20690116 Hum. Mutat. 2010 10.1002/humu.21329 5 0 0 41 Encephaloclastic Proliferative Vasculopathy|Hydranencephaly|*High-Throughput Nucleotide Sequencing|*Mutations|*Genetic Linkage|*Cerebrovascular Disorders|Pedigree|Membrane Transport Proteins|Brain|Amino Acid Sequence|Vascular Diseases|Receptors, Virus|SNPs 22 FLVCR2 20518025 Hum. Mutat. 2010 10.1002/humu.21293 40 1 2 41 Humans|*Exome|*Mutations|*Sequencing, Next-Generation|DNA Mutational Analysis|Exons|Sequence Analysis, DNA|Pedigree|Introns|Phenotype|Encephaloclastic Proliferative Vasculopathy|*Hydranencephaly|Genome, Human|Open Reading Frames|FLVCR2 protein, human|Receptors, Virus|Membrane Transport Proteins 22 FLVCR2 20206334 Am. J. Hum. Genet. 2010 PMC2833392 10.1016/j.ajhg.2010.02.004 15 0 0 41 Pregnancy|Female|Humans|Encephaloclastic Proliferative Vasculopathy|*Hydranencephaly|*Hydrocephaly|*Syndrome|*Mutations|Fetal Diseases|*Vascular Diseases|Pena Shokeir syndrome, type 1|Arthrogryposis|Brain|Membrane Transport Proteins|Receptors, Virus|Genetic Linkage|FLVCR2 protein, human 22 foxd4 20650821 Hum. Genomics 2010 PMC3500164 10.1186/1479-7364-4-5-345 66 5 5 58 Mice|Humans|Animals|Evolution, Molecular|Phylogeny|Sequence Alignment|Forkhead Box Transcription Factors|Multigene Family|Genome, Human|Amino Acid Sequence 27 FOXJ3 20223197 Neuron 2010 PMC2843397 10.1016/j.neuron.2010.01.027 198 23 14 127 Mice|Animals|DICER1 protein, human|*Ribonuclease III|*DEAD-box RNA Helicases|Oligodendroglia|Cell Differentiation|Myelin Sheath|Mice, Transgenic|Basic Helix-Loop-Helix Transcription Factors|Myelin Basic Protein|Stem Cells|Gene Expression Regulation, Developmental|Transcription Factors|Oligodendrocyte Precursor Cells|MicroRNAs|Cells, Cultured|Nerve Tissue Proteins|Embryo, Mammalian|*Neurogenesis 21 GAGE1 20423514 BMC Cancer 2010 PMC2868811 10.1186/1471-2407-10-163 12 2 0 20 Female|Humans|*Ovarian Cancer|*Antigens, Neoplasm|*Epithelial Ovarian Cancer|Melanoma-Specific Antigens|Neoplasm Proteins|Biomarkers, Tumor|Prognosis|Gene Expression Regulation, Neoplastic|RNA, Messenger|Gene Expression|*Cell Lines 48 GAGE1 20053773 Mol. Cancer Ther. 2010 PMC2806502 10.1158/1535-7163.MCT-09-0486 33 18 4 20 Humans|Male|AR protein, human|Androgen Receptor|CpG Islands|*Prostate Cancer|Methylations, DNA|Promoter Regions, Genetic|Decitabine|Azacitidine|Prostate|Gene Expression Regulation, Neoplastic|Transcription Factor|Cell Line, Tumor|Genes, p16 48 GIMAP4 20421878 Immunol. Cell Biol. 2010 10.1038/icb.2010.57 11 7 2 68 Humans|*Lymphocyte Activation|Nuclear Factor-Kappab|Interleukine 2|Nuclear Proteins|CD28 Antigens|Transcription Factor AP-1|Cell Nucleus|NFATC Transcription Factors|Promoter Regions, Genetic|Gene Expression|Jurkat Cells|Cytokines|RNA, Small Interfering 29 GIMAP4 20175888 BMC Genomics 2010 PMC2838843 10.1186/1471-2164-11-125 14 6 1 68 Humans|*Myotubes|*Gene Expression Profiling|*Muscle, Skeletal|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation|RNA, Messenger|Cells, Cultured|Cell Line 29 GMFB 20547056 Eur. J. Cancer 2010 10.1016/j.ejca.2010.04.015 15 2 2 125 Humans|Female|*Prognosis|*Glia Maturation Factor|*Carcinoma, Ovarian Epithelial|Proteomics|*Cystadenocarcinoma, Serous|Ovarian Neoplasms|Immunohistochemistry|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease-Free Survival|Neoplasm Staging|Survival Rate|Disease Progression 26 GOLGA3 20170975 Diabetes Res. Clin. Pract. 2010 10.1016/j.diabres.2010.01.018 3 1 0 189 Humans|*Autoantigens|*Diabetes Mellitus, Type 1|*Protein Disulfide-Isomerases|*Golgi Matrix Proteins|*Voltage-Gated Potassium Channel|*Epitopes|Receptor-Like Protein Tyrosine Phosphatases, Class 8|Autoantibodies|Islets of Langerhans|Protein Tyrosine Phosphatases|Amino Acid Sequence|Membrane Proteins 46 GPR64 21618837 Adv. Exp. Med. Biol. 2010 10.1007/978-1-4419-7913-1_16 2 0 0 39 Male|Animals|Mice|Epididymis|Receptors, G-Protein-Coupled|*Male Reproductive System|Mice, Knockout 28 HMG20B 20530487 J. Biol. Chem. 2010 PMC2915710 10.1074/jbc.M109.090654 10 5 2 74 Chlorocebus aethiops|Animals|Mice|dystrobrevin|*Dystrophin-Associated Proteins|Protein Isoforms|Membrane Proteins|Two-Hybrid System Techniques|Neurons|Protein Binding|Synapsin I|Signal Transduction|Cloning, Molecular|Transfection|Transcription Factors|cDNA Library|Brain|COS Cells|High Mobility Group Proteins|Hmg20a protein, mouse 22 HMGN3 20842223 J Cancer 2010 PMC2931353 10.7150/jca.1.38 13 0 0 72 Humans|*Transcriptome Analysis|Genes, Tumor Suppressor|Loss of Heterozygosity|Cell Line, Tumor|Chromosome Mapping|Microarray Analysis|*Chromosome Structures|RNA, Messenger|Downregulation|Gene Transfer Techniques|Upregulation|Phenotype|PTK7 protein, human|Cell Adhesion Molecules|Receptor Protein-Tyrosine Kinases 28 HMGN3 20300989 Methods Mol. Biol. 2010 10.1007/978-1-60761-629-0_3 1 0 0 72 *Reverse Transcriptase Polymerase Chain Reaction|*Transcriptome Profiling|DNA Microarray|mRNA|Transcription, Genetic|Gene Expression Regulation|Cell Cycle|Enterovirus|Cell Death|Cytoskeleton|*Host Microbe Interaction 28 hus1b 20816984 J. Mol. Biol. 2010 PMC2953589 10.1016/j.jmb.2010.08.045 29 18 1 18 Humans|*Eukaryotes|DNA Repair|DNA Glycosylases|Schizosaccharomyces pombe|xeroderma pigmentosum group F protein|*DNA-Binding Proteins|Schizosaccharomyces pombe Proteins|DNA Damage|Cell Cycle Proteins|Exonucleases|RRAD protein, human|*ras Proteins|Protein Binding|*Eukaryotic Cells 32 hus1b 20188637 DNA Repair (Amst.) 2010 PMC2860068 10.1016/j.dnarep.2010.01.011 13 47 0 18 Humans|HeLa Cells|*DNA Mismatch Repair|rad9 protein|Cell Cycle Proteins|G-T mismatch-binding protein|*DNA-Binding Proteins|xeroderma pigmentosum group F protein|DNA Repair|Proliferating Cell Nuclear Antigen|Exonucleases|Schizosaccharomyces pombe Proteins|DNA Glycosylases|DNA Damage|Schizosaccharomyces pombe|Protein Binding|Binding Sites|Cell Cycle|RRAD protein, human 32 IGIP 21074276 Vet. Immunol. Immunopathol. 2010 10.1016/j.vetimm.2010.10.009 4 3 0 16 Mice|Cattle|Humans|Animals|Swine|TNFSF13B protein, human|B-Cell Activating Factor|TNFSF13 protein, human|Tumor Necrosis Factor Ligand Superfamily Member 13|Immunoglobulin Class Switching|Secretory IgA|Immunoglobulin Isotypes|B-Lymphocytes|Immunity, Mucosal|Immunoglobulin A|T Cells|Cytokines|Transforming Growth Factor beta 29 IGSF3 20621762 Placenta 2010 10.1016/j.placenta.2010.05.004 21 0 1 44 Humans|Rats|Female|Pregnancy|Animals|*Placenta|*Placental Insufficiency|Pre-Eclampsia|Intrauterine Growth Restriction|*Gene Expression|Oligonucleotide Array Sequence Analysis|Renin-Angiotensin System|Gene Expression Profiling|Rats, Inbred BN 20 IGSF3 20142997 Cancer Cell Int. 2010 PMC2817686 10.1186/1475-2867-10-2 16 2 1 44 Humans|*Real-Time Polymerase Chain Reaction|*Lung Cancers|*Gene Expression Profiling|Carcinoma, Non-Small-Cell Lung|DNA Microarrays|Adenocarcinoma|Small Cell Lung Carcinoma|Carcinoma, Small Cell|Carcinoma, Large Cell|Squamous Cell Carcinoma|Gene Expression Regulation, Neoplastic|Antigens, Neoplasm|Cell Line, Tumor 20 IMPG1 20655080 Virology 2010 10.1016/j.virol.2010.06.040 5 0 0 26 Humans|EBV-encoded nuclear antigen 1|*Epstein-Barr Virus Nuclear Antigens|*Genome, Human|Epstein Barr Virus|Binding Sites|Virus Replication|DNA Replication|DNA-Binding Proteins|Protein Binding|DNA, Viral|Regulatory Regions|Cell Line 29 INSL4 21082170 J. Mol. Evol. 2010 10.1007/s00239-010-9403-6 8 0 2 17 Female|Pregnancy|Animals|*Relaxin|*Placental Mammals|*Insulin|*Insulin, Regular, Human|Gene Duplication|Evolution, Molecular|Phylogeny|Sequence Alignment|Vertebrates|Multigene Family|Amino Acid Sequence 45 ISL2 21190559 BMC Neurosci 2010 PMC3019204 10.1186/1471-2202-11-155 0 1 0 74 Mice|Animals|Superior Colliculus|Retinal Ganglion Cells|Receptor, EphA3|Visual Pathways|Receptors, Eph|Axons|EPHA3 protein, human|Retina|Ephrins 55 ISM1 25009716 Facts Views Vis Obgyn 2010 PMC4086013 3 0 0 121 Pregnancy|Humans|Female|*Pilot Projects|Embryo Culture Techniques|Embryo Transfer|Fertilization in Vitro|Pregnancy Rate|Sperm Injections, Intracytoplasmic|*Embryo, Mammalian|Blastocyst|Embryo Implantation|Culture Media|Embryonic Development 26 ITM2C 20198315 Int. J. Mol. Med. 2010 10.3892/ijmm_00000388 10 0 0 80 Humans|Genome-Wide Association Study|Japan|*Intracranial Hemorrhages|Stroke|Genetic Predisposition to Disease|Brain Ischemia|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Gene Frequency|Cerebral Hemorrhage|Genotypes|Risk Factors|Myocardial Infarction|Case-Control Studies|Gene Chip|Subarachnoid Hemorrhage|Logistic Models 27 KLF16 21171965 Biochem. J. 2010 PMC3130109 10.1042/BJ20100773 32 41 6 93 *Proto-Oncogene Proteins p21(ras)|Transcription Factors|*K-ras Oncogenes|Kruppel-Like Transcription Factors|Repressor Proteins|Trans-Activators|Promoter Regions, Genetic|Cell Division|Cyclin|*Cell Cycle|Cancers 26 KLRC4 20811687 Oncol. Rep. 2010 10.3892/or.2010.1043 2 5 0 16 Animals|Humans|Mice|IL15 protein, human|*Interleukin-15|*Interleukin-2|*Up-Regulation|Escherichia coli|Chromatography, Liquid|*BALB C Mice|Tandem Mass Spectrometry|*Natural Killer Cells|NK Cell Lectin-Like Receptor Subfamily D|NK Cell Lectin-Like Receptor Subfamily C|Receptors, Natural Killer Cell|Lectin, C-Type|Flow Cytometry|Antigens, CD|Cell Line 24 KLRC4 20648603 J. Med. Virol. 2010 10.1002/jmv.21855 7 0 1 16 Humans|*Hepatitis B, Chronic|*NK Cell Lectin-Like Receptor Subfamily K|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|B virus, Hepatitis|Genetic Predisposition to Disease|Hepatitis B Virus Infection|Gene Frequency|Restriction Fragment Length Polymorphism|Genotype|Haplotypes|Chromosome Mapping|Polymerase Chain Reaction|Receptors, Natural Killer Cell 24 LGALS12 21187013 BMC Syst Biol 2010 PMC3022651 10.1186/1752-0509-4-175 8 10 1 461 *Computational Biology|*Adipose Tissue|*Gene Expression|Obesity|Nerve Tissue Proteins|*Module, Gene|Membrane Proteins|*Diet|Insulin Resistance|Gene Expression Profiling|Inflammation 24 LRWD1 21029866 Cell 2010 PMC3640253 10.1016/j.cell.2010.10.012 222 23 14 85 *Nucleosomes|*Histones|Proteomics|*Protein Processing, Post-Translational|Jumonji Domain-Containing Histone Demethylases|Lysine|Chromatin|Histone Demethylases|*DNA|DNA Methylation|TYRP1 protein, human|DNA-Binding Proteins|*Membrane Glycoproteins|F-Box Proteins 22 LRWD1 20932478 Mol. Cell 2010 PMC5201136 10.1016/j.molcel.2010.09.021 53 12 1 85 Humans|*Origin Recognition Complex|*Chromatin|Heterochromatin|DNA Replication|Cell Nucleus|Cell Cycle|G1 Phase|Protein Binding|*Transcription Factors|Cell Division|HeLa Cells|Sequestosome-1 Protein|LRWD1 protein, human|Microtubule Proteins 22 METRN 20840868 Neurobiol. Dis. 2010 10.1016/j.nbd.2010.09.003 9 0 2 47 Rats|Animals|*Quinolinic Acid|*Corpus Striatum|Huntington Disease|*Neurons|Ciliary Neurotrophic Factor|Lentivirus|Genetic Vectors|Nerve Tissue Proteins|Neuroprotective Effects|Genetic Therapy|Disease Models, Animal|Choline O-Acetyltransferase 22 MIDN 20977639 Am. J. Transplant. 2010 10.1111/j.1600-6143.2010.03281.x 6 0 3 245 Humans|*Living Donors|*Follow-Up Studies|Quality of Life|*Tissue and Organ Harvesting|*Laparoscopy|Nephrectomy|*Kidney|Kidney Transplantation|Graft Survival|Glomerular Filtration Rate|*Surgical Wound|Length of Stay|Fatigue 23 MIDN 20623358 Hum. Genet. 2010 10.1007/s00439-010-0859-7 11 0 1 245 Humans|Syndrome, Peutz-Jegher's|Mutations, Germline|STK11 protein, human|Protein-Serine-Threonine Kinases|Exons|Point Mutation|Phenotype|Gene Deletion|*Complement Factor B|DNA Sequencing|ATP5D protein, human 23 MPZL2 21152390 PLoS ONE 2010 PMC2994754 10.1371/journal.pone.0014168 32 5 2 144 Male|Mice|Animals|AR protein, human|*Receptors, Androgen|*Sertoli Cells|Spermatogenesis|Testis|Spermatogonia|*Cell Differentiation|Androgens|*Cytoskeleton|Mice, Knockout|*Sex Differentiation|Actn3 protein, mouse|Actinin 22 MPZL2 20463920 PLoS ONE 2010 PMC2864763 10.1371/journal.pone.0010480 41 2 2 144 Humans|*Human Embryonic Stem Cells|Embryonic Stem Cells|MicroRNAs|Lineages, Cell|Cell Differentiation|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Oligodendrocyte|*Neurogenesis|Gene Expression|Cells, Cultured|Myelin 22 MTX3 28883761 J. Asia Pac. Entomol. 2010 PMC5584542 10.1016/j.aspen.2010.03.002 4 9 0 133 Animals|Bacillus thuringiensis|Endotoxins|Hemolysin Proteins|Culex|Pest Control, Biological|Bacillus|Insecticides|Bacterial Proteins|Larva 21 myo1f 20071333 J. Biol. Chem. 2010 PMC2838290 10.1074/jbc.M109.086959 31 0 2 128 *Myosin I|platelet protein P47|*Pleckstrin Homology Domain|*Myosin B|*Myosin|Blood Proteins|Phosphoproteins|*Plasma Membrane|Actin|Phosphatidylinositol|Protein Binding|Protein Structure, Tertiary|Binding Site|Actin Cytoskeleton|Amino Acid Sequence|*Lymphocytes 25 MYO5C 20972619 Cytotechnology 2010 PMC3021151 10.1007/s10616-010-9315-8 11 0 2 604 Endothelial Cells|Gene Expression Profiling|Cell Lines|*Biomarkers|*Genetic Profile|Cell Differentiation|mRNA 22 ncln 20538592 J. Biol. Chem. 2010 PMC2924024 10.1074/jbc.M110.132548 8 2 1 65 Animals|gamma-Secretase|Presenilin|Aspartic Acid Endopeptidases|Membrane Proteins|Amyloid beta-Protein Precursor|Membrane Glycoproteins|Zebrafish|Endoplasmic Reticulum|Signal Transduction|Cell Line|Cell Membrane|Transforming Growth Factor beta 21 NDFIP2 20959604 Blood 2010 10.1182/blood-2010-07-295287 19 0 3 108 Mice|Animals|solute carrier family 11- (proton-coupled divalent metal ion transporters), member 2|Cation Transport Proteins|Iron|*Homeostasis|Iron Overload|Membrane Proteins|Enterocytes|Ubiquitination|Liver|Cations, Divalent|Biological Transport|Ndfip1 protein, mouse|Carrier Proteins|NDFIP2 protein, mouse 24 NDFIP2 20682038 Virol. J. 2010 PMC2922189 10.1186/1743-422X-7-179 10 36 1 108 *Ubiquitin|Nedd4 Proteins|Endosomal Sorting Complexes Required for Transport|Ubiquitin-Protein Ligases|Ubiquitination|Viral Proteins|Carrier Proteins|Membrane Proteins|Protein Binding|Herpesvirus 2, Human|Repressor Proteins|Cell Line 24 NDFIP2 20534535 Proc. Natl. Acad. Sci. U.S.A. 2010 PMC2895104 10.1073/pnas.0911714107 24 14 1 108 Humans|*Proto-Oncogene Proteins c-akt|*MAP Kinase Signaling System|HeLa Cells|*Ubiquitination|PTEN protein, human|*PTEN Phosphohydrolase|E3 Ubiquitin Ligase|Endosomal Sorting Complexes Required for Transport|Nedd4 Ubiquitin Protein Ligases|Carrier Proteins|Membrane Proteins|Signal Transduction|Phosphorylation|EGFR protein, human|Receptor, EGF|Ubiquitins|NDFIP1 protein, human 24 NDFIP2 20522958 Biol. Pharm. Bull. 2010 10.1248/bpb.33.951 3 7 0 108 GJA1 protein, human|*Connexin 43|*Membrane Protein|*Down-Regulation|*Half-Life|*Lysosomes|Ubiquitylation|Endosomal Sorting Complexes Required for Transport|Gap Junctions|Nedd4 Ubiquitin Protein Ligases|Ubiquitin|Ubiquitin-Protein Ligases|Golgi Apparatus|Protein Binding|RNA, Small Interfering 24 NDFIP2 20363515 Aquat. Toxicol. 2010 10.1016/j.aquatox.2010.03.006 8 0 0 108 Animals|Female|*Ovary|*Cyprinidae|Oligonucleotide Microarray|Gene Expression|Follicles, Atretic|Toxicogenomics|Reproduction|Ovulation|RNA, Messenger 24 NDFIP2 20090362 Kidney Blood Press. Res. 2010 10.1159/000275706 12 2 1 108 Humans|*Sodium|*Blood Pressure|Sodium Channel, Epithelial|Endosomal Sorting Complexes Required for Transport|E3 Ubiquitin Ligase|Nedd4 Ubiquitin Protein Ligases|Ubiquitination|*Hypertension|Immediate-Early Proteins|*Blood Pressure Determination|Protein-Serine-Threonine Kinases|Phosphorylation|HEK293 Cells|Signal Transduction|Ion Transport|Genetic Variation|USP2 protein, human|Endopeptidases 24 NHLH1 21131441 Am. J. Respir. Cell Mol. Biol. 2010 PMC3175565 10.1165/rcmb.2010-0342OC 19 0 3 132 Humans|Animals|Mice|*Lipopolysaccharides|*Mice, Inbred C57BL|*Mice, Inbred C3H|Hedgehog Proteins|Toll-Like Receptor 4|Macrophages|Signal Transduction|Immunity, Innate|Cytokines|Inflammation|Spleen|Oligonucleotide Microarrays|Liver|Tumor Necrosis Factor-alpha|RNA, Messenger|Blotting, Western|Lung|HOXA4 protein, human 43 OTOP1 20554841 J. Neurophysiol. 2010 PMC3007624 10.1152/jn.00525.2010 18 1 1 24 Animals|Mice|*Vestibule, Labyrinth|Otoconia|*Calcium, Dietary|*Minerals|Calcium Carbonate|Adenosine Triphosphate|Membrane Proteins 23 OTOP1 20423468 BMC Dev. Biol. 2010 PMC2873407 10.1186/1471-213X-10-42 7 2 0 24 Animals|*Zebrafish|*Gastrula|Zebrafish Proteins|Embryo, Nonmammalian|Nodal Signaling Ligands|Endoderm|Mesoderm|Gene Expression Regulation, Developmental|Embryogenesis|Syncytium|Intracellular Signaling Peptides and Proteins|Cell Nucleus|Egg Yolk 23 PARM1 20305782 PLoS ONE 2010 PMC2841187 10.1371/journal.pone.0009746 25 43 2 49 Male|Rats|Animals|*Endoplasmic Reticulum Stress|*Myocytes, Cardiac|*Prostate|*Dahl Salt-Sensitive Rats|*Endoplasmic Reticulum|*Apoptosis|Tunicamycin|Activating Transcription Factor 6|Transcription Factor CHOP|Caspase 12|Thapsigargin|Cardiac Hypertrophy|Heat-Shock Proteins|Signal Transduction|Molecular Chaperones|Membrane Proteins|siRNA|*Androgens 20 pax6a 21123457 Clin. Cancer Res. 2010 PMC3076314 10.1158/1078-0432.CCR-10-1260 46 14 5 0 Humans|*Rubus|*Pilot Projects|*Colorectal Cancer|*Colonic Neoplasms|DNA Methylation|Wnt Pathway|DNA (Cytosine-5-)-Methyltransferases|Promoter Regions, Genetic|Colon|Epigenesis, Genetic|*Epigenetic|Rectum|Cell Proliferation|*Biomarkers 32 pax6a 20621053 Cell Stem Cell 2010 PMC2904346 10.1016/j.stem.2010.04.017 153 36 13 0 Humans|Mice|Animals|*Neural Plate|*Cell Differentiation|Paired Box Transcription Factors|Homeodomain Proteins|Eye Proteins|Embryonic Stem Cells|Repressor Proteins|PAX6 Transcription Factor|Gene Expression Regulation|Cell Line|Neuroepithelial Cells|PAX6 protein, human|Pax6 protein, mouse 32 pax6a 20549742 Dev. Dyn. 2010 10.1002/dvdy.22325 10 0 1 0 Animals|*Zebrafish|CTNNB1 protein, human|beta Catenin|Wnt Proteins|AXIN2 protein, human|Axin Protein|Adenomatous Polyposis Coli Protein|*Adenomatous Polyposis Coli|Signal Transduction|Mutation|Apoptosis|*Eyes 32 pax6a 20152834 Exp. Eye Res. 2010 PMC2856924 10.1016/j.exer.2010.02.001 58 0 2 0 Animals|*Zebrafish|Photoreceptors, Cone|Zebrafish Proteins|Retina|Retinal Rod Photoreceptor Cells|Glial Cell|Animals, Genetically Modified|Progenitor Cell|In Situ Nick-End Labeling|Cell Proliferation|Protein, Pax-6|Apoptosis|Nerve Regeneration|Retinal Diseases 32 pdia2 20448108 Blood 2010 PMC2924232 10.1182/blood-2009-10-249607 56 4 1 61 *Protein Disulfide-Isomerases|*Phosphatidylserines|*Endothelial Cells|*Blood Coagulation|Tissue Factor Procoagulant|Factor VIIa|prothrombinase complex|Factor Xa|TYRP1 protein, human|*Oxidoreductases|*Membrane Glycoproteins|Thrombosis|Redox|Disulfides|Signal Transduction|Protein Binding|Annexin V|Cell Membrane 23 PDZRN3 20668165 Mol. Biol. Cell 2010 PMC2938391 10.1091/mbc.E10-02-0117 12 53 0 80 Mice|Animals|*Wnt Signaling Pathway|BMP2 protein, human|*Bone Morphogenetic Protein 2|*Cell Differentiation|*Osteogenesis|Osteoblasts|Bone Morphogenetic Proteins|beta Catenin|Core Binding Factor Alpha 1 Subunit|Wnt3A Protein|Transforming Growth Factor beta|Progenitor Cells, Mesenchymal|Alkaline Phosphatase|Cell Line|Up-Regulation|RNA Interference|Adipocytes|PDZRN3 protein, mouse 26 PDZRN3 20633763 Cancer Genet. Cytogenet. 2010 10.1016/j.cancergencyto.2010.04.018 2 1 0 80 *Carcinoma, Renal Cell|Comparative Genomic Hybridization|Kidney Neoplasms|Translocation, Genetic|Chromosome Aberrations|In Situ Hybridization, Fluorescence|Mutation|*Carcinogenesis|Heterozygote|Allele|*Germ Line 26 pkd1l1 20080492 Vet. Pathol. 2010 10.1177/0300985809353553 26 0 1 17 Male|Mice|Animals|*Situs Inversus|Primary Ciliary Dyskinesia|Cilia|polycystic kidney disease 1 protein|TRPP Cation Channels|Body Patterning|Respiratory Tract|Disease Models, Animal|Potter Type III Polycystic Kidney Disease|Polycystic Kidney Diseases|Hydrocephalus 20 Pl15 21098871 Pharmacol Rep 2010 10.1016/s1734-1140(10)70348-0 1 0 0 0 23 PLAC4 21090641 Bioconjug. Chem. 2010 10.1021/bc1002949 5 0 1 0 locked nucleic acid|*RNA|*Fluorescence|*Oligonucleotides|*Nucleic Acid Hybridization|Nucleic Acid Conformation|Nucleic Acid Probes|Spectrometry, Fluorescence|Fluorescent Dyes|RNA Sequence|Nucleotides|*Hybridization, Genetic 22 POU6F1 20134265 Int. J. Gynecol. Cancer 2010 10.1111/IGC.0b013e3181c97ae0 4 1 1 30 Humans|Female|*Adenocarcinoma, Clear Cell|*Ovary|Ovarian Neoplasms|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|3'-(1-butylphosphoryl)adenosine|RNA, Small Interfering|Apoptosis|RNA, Messenger|Blotting, Western|Anticancer Agents|*Complement Factor B|Transcription Factors|Cell Proliferation|Japan 34 PTPRCAP 20505096 J. Neurosci. 2010 PMC2932640 10.1523/JNEUROSCI.6151-09.2010 23 27 2 34 Mice|Animals|*Receptors, Lysophosphatidic Acid|*Calcium Signaling|sphingosine 1-phosphate|Lysophospholipids|lysophosphatidic acid|Sphingosine|*Neurogenesis|*Cerebral Cortex|*Calcium, Dietary|*Cytoplasm|Type C Phospholipases|Thapsigargin|Cultured Cells|Pertussis Toxin|Cell Differentiation|Estrenes 48 RAPGEF6 20800573 Biochem. Biophys. Res. Commun. 2010 PMC2954587 10.1016/j.bbrc.2010.08.092 21 37 1 96 *Guanine Nucleotide Exchange Factor|*Cell Adhesion|Apoptosis Regulatory Proteins|RASGRF1 protein, human|*ras-GRF1|Adaptor Proteins, Signal Transducing|Cell Motility|Protein Binding|Actin|Cell Line, Tumor 25 RAX2 20678480 Biochem. Biophys. Res. Commun. 2010 10.1016/j.bbrc.2010.07.102 1 3 0 14 *Saccharomyces cerevisiae|*Diploidy|*Bipolar Disorder|Saccharomyces cerevisiae Proteins|Membrane Glycoproteins|Membrane Proteins|Cell Polarity|Cell Division|Green Fluorescent Proteins|Protein Transport|Luminescent Proteins|Actins|Reproduction, Asexual 25 Resp18 21104147 Mol. Biol. Rep. 2010 10.1007/s11033-010-0394-6 0 0 0 423 Mice|Animals|regulated endocrine secretory protein 18|*Nerve Tissue Proteins|*Protein Isoforms|mRNA|Amino Acid Sequence 23 Resp18 20944418 Biosci. Biotechnol. Biochem. 2010 10.1271/bbb.100349 4 0 0 423 Animals|Humans|*Secretory Vesicles|*Glutamyl Aminopeptidase|Islet Cells|*Syntenies, Conserved|*Genetic Evolution|*Pancreas, Exocrine|Proteins|Caenorhabditis elegans|Electron Microscopy|Signal Transduction 23 RHBDF1 20961401 BMC Evol. Biol. 2010 PMC2975663 10.1186/1471-2148-10-315 8 1 0 79 Animals|*Gadus morhua|*Chordates|*Vertebrate|*Genome|*Genomics|*Gene Expression|Phylogeny|alpha-Globins|Evolution, Molecular|Multigene Family|beta-Globins|Amino Acid Sequence|Fishes|Arctic Regions 30 RIMS2 20520587 Psychiatr. Genet. 2010 PMC3832188 10.1097/YPG.0b013e32833a2106 26 0 2 81 Humans|*Genome-Wide Association Study|*Heroin Dependence|Gene Frequency|Genetic Predisposition to Disease|Linkage Disequilibrium|European Continental Ancestry Group|Polymorphism, Genetic|Genotype|African Americans|Case-Control Studies 35 RNF39 20875797 Biochem. Biophys. Res. Commun. 2010 10.1016/j.bbrc.2010.09.088 12 1 0 8 Humans|*HLA-B51 Antigen|HLA-B Antigens|Behcet Disease|Single Nucleotide Polymorphisms|Alleles|Genetic Predisposition to Disease|Gene Frequency|Haplotypes|Exon|TRIM39 protein, human|Carrier Proteins|RNF39 protein, human|Immediate-Early Proteins 22 RNF39 20192730 Clin. Infect. Dis. 2010 10.1086/651114 24 0 2 8 Humans|*Human immunodeficiency virus 1|*Zinc|HIV Infections|Viral Load|Virus Replication|Short Interfering RNA|RNA, Viral|*Disease Progression|ZNRD1 protein, human|DNA-Binding Proteins 22 SAMSN1 20478393 Int. J. Biochem. Cell Biol. 2010 10.1016/j.biocel.2010.05.004 5 6 0 51 Endothelial Cells|HDAC1 protein, human|*Histone Deacetylase 1|*Cell Nucleus|Cytoplasm|Histone Deacetylases|Transcription Factors|Transcription, Genetic|Repressor Proteins|Protein Binding|Transfection|Protein Structure, Tertiary|Phosphorylation|Transcriptional Activation|Cytosol|Upregulation 25 SCAMP2 20514246 Plant Signal Behav 2010 PMC2819456 10.4161/psb.4.12.10075 2 0 0 316 *Protein Transport|*Endocytosis|Golgi Apparatus|Secretory Vesicles|Plasma Membrane|Exocytosis|Carrier Proteins|Tobacco|Biological Transport|Cytoplasm|Membrane Proteins|Membrane Transport Proteins|*Cell Movement 26 SEZ6L 20424129 Cancer Prev Res (Phila) 2010 10.1158/1940-6207.CAPR-09-0141 18 0 2 15 *Lung Cancer|Case-Control Studies|Single Nucleotide Polymorphism|Receiver Operating Characteristic|Risk Factors|Genetic Predisposition to Disease|Area Under Curve|Logistic Regression|Risk Assessment|Genotype 21 SH3PXD2B 20137777 Am. J. Hum. Genet. 2010 PMC2820172 10.1016/j.ajhg.2010.01.009 37 0 6 105 Humans|Child|Mice|Animals|Ter Haar syndrome|*Podosomes|Homozygote|Sequence Deletion|*Craniofacial Abnormalities|*Osteochondrodysplasias|*Heart Defects, Congenital|*Developmental Disabilities|*Adaptor Proteins, Signal Transducing|Eye Abnormalities|DNA Mutational Analysis|*Musculoskeletal Abnormalities|Mutation|Glaucoma|Phenotype|Tks4 protein, human|Tks4 protein, mouse|Phosphoproteins 23 SHROOM2 20332152 Development 2010 10.1242/dev.045138 18 0 2 47 Mice|Animals|*Hair Cells, Auditory, Outer|Organ of Corti|Cochlea|Hearing|Microscopy, Electron, Scanning|Cilia|Organelle|Cytoskeleton 26 SLC16A12 21044875 Gene 2010 10.1016/j.gene.2010.10.011 18 0 2 24 Humans|Animals|*Organ Specificity|*Biological Evolution|*Membrane Transport Proteins|Genetic Evolution|Phylogeny|Genome, Human|Bioinformatic|Slc10a6 protein, human|Organic Anion Transporters 24 SLC22A9 20829431 Mol. Pharmacol. 2010 10.1124/mol.110.065201 7 1 0 139 Humans|*Hepatocyte Nuclear Factor 1|*Organic Anion Transporters|Hepatocytes|Organic Anion Transporters, Sodium-Independent|Liver|Promoter Regions, Genetic|Transcriptional Activation|Hepatocyte Nuclear Factor 1-alpha|Transcription Start Site|Chromatin Immunoprecipitation|Reporter Gene|Cell Line, Tumor 30 SLC22A9 20639259 Toxicol. Sci. 2010 10.1093/toxsci/kfq219 20 0 0 139 Humans|urate transporter|perfluorooctanoic acid|*Renal Reabsorption|*Organic Anion Transporters|*Caprylates|*Fluorocarbons|*Biological Transport|Organic Anion Transporters, Sodium-Independent|Organic Cation Transport Proteins|estrone sulfate|Estrone|Cell Line|Transfections|Kidney|Kinetics|Uric Acid|Anions 30 SLC22A9 20360303 Drug Metab. Dispos. 2010 10.1124/dmd.109.031526 5 0 1 139 Humans|Dogs|Animals|HEK293 Cells|*Renal Agents|SLC22A2 protein, human|Organic Cation Transporter 2|Organic Anion Transport Protein 1|Organic Anion Transporters, Sodium-Independent|Organic Anion Transporters|Organic Cation Transport Proteins|Probenecid|*Ethinyl Estradiol|Biological Transport|Biological Transport, Active|Cimetidine|Tubule, Proximal Renal|Kidney|ATP-Binding Cassette Transporters|Madin Darby Canine Kidney Cells|*Sulfates 30 SPANXA1 20839415 Eur J Histochem 2010 PMC3167315 10.4081/ejh.2010.e41 7 0 1 37 Humans|Male|*Prostate|Prostate cancer, familial|*Prostate Cancer|Nuclear Proteins|Genetic Linkage|Immunohistochemistry|Chromosomes, Human, X 27 SPANXA1 20073942 Syst Biol Reprod Med 2010 10.3109/19396360903312015 3 0 0 37 Humans|Male|Child|DNA Copy Number Variations|*Infertility, Male|*Fertility|Spermatogenesis|Spermatozoa|Nuclear Proteins 27 STK17B 21148796 J. Immunol. 2010 PMC3133617 10.4049/jimmunol.1000942 5 53 0 215 Mice|Animals|protein kinase D|*Protein Kinase C|AKT1 protein, human|*Protein Kinase B|Lymphocyte Activation|T Cells|Receptors, Antigen, T-Cell|Signal Transduction|*Mitochondria|Encephalomyelitis, Autoimmune, Experimental|Immunologic Memory|Phosphorylation|Oxygen|Drak2 protein, mouse|Protein-Serine-Threonine Kinases 32 STK17B 21143916 BMC Genomics 2010 PMC3016419 10.1186/1471-2164-11-699 6 3 0 215 Humans|Male|Swine|Animals|*Acrosome|*Chromosomes, Human, Pair 15|Spermatozoa|Infertility, Male|Sus scrofa|Chromosomes, Mammalian|Polymorphism, Single Nucleotide|Sequence Analysis, DNA|HECW2 protein, human|Ubiquitin-Protein Ligases 32 STK17B 20056315 Cancer Lett. 2010 10.1016/j.canlet.2009.12.007 3 4 1 215 *TNF-Related Apoptosis-Inducing Ligand|*Antibodies, Monoclonal|Receptors, TNF-Related Apoptosis-Inducing Ligand|Apoptosis|CASP8 protein, human|Caspase 8|Cell Line, Tumor|Tumor Necrosis Factor-alpha|*Biomarkers 32 STOML1 20060952 Osteoarthr. Cartil. 2010 PMC2877870 10.1016/j.joca.2009.11.015 17 3 0 71 *Protease Inhibitor|Cartilage, Articular|Chondrocytes|*Neovascularization, Pathologic|Osteoarthritis, Knee|Vascular Endothelial Growth Factor A|Matrix Metalloproteinase 9 20 TARBP1 20686683 PLoS Comput. Biol. 2010 PMC2912335 10.1371/journal.pcbi.1000864 23 0 4 41 Phylogeny|*Proteins|Protein Conformation|Protein Folding|Models, Molecular 26 TARBP1 20608175 Mol. Biol. (Mosk.) 2010 0 0 0 41 Humans|*Thymidine Kinase|*HIV-1|*Tumor Suppressor Protein p53|*Promoter Regions, Genetic|Ganciclovir|TAR Element, HIV|Simplexvirus|tat Gene|Genetic Vectors|Genetic Therapy|Transfection|Telomerase|BIRC5 protein, human|Survivin|Cytomegalovirus|Tumor Cells, Cultured 26 TCF15 21111815 Mech. Dev. 2010 10.1016/j.mod.2010.11.005 6 0 1 58 Mice|Animals|*Notochord|*Mice, Inbred C57BL|*Spine|Somite|Gene Expression Regulation, Developmental|Paired Box Transcription Factors|Cell Differentiation|Mutation|Mutagenesis 39 TEX19 21103378 PLoS ONE 2010 PMC2982839 10.1371/journal.pone.0014017 16 8 0 48 Mice|Male|Female|Animals|*Ubiquitin|*Spermatogenesis|Ubiquitin Ligase E3|Ubiquitination|Spermatocytes|Proteins|Mice, Knockout|UBR2 protein, mouse|Tex19 protein, mouse|Nuclear Proteins 20 TMEM135 21151927 PLoS ONE 2010 PMC2997067 10.1371/journal.pone.0014228 13 14 2 40 Humans|Child|Mice|Animals|*Caenorhabditis elegans|*Gene Regulatory Networks|*Mice, Inbred C57BL|VLCAD deficiency|Very Long Chain Acyl CoA Dehydrogenase|Lipid Metabolism, Inborn Errors|Mitochondrial Diseases|Muscular Diseases|*Longevity|Energy Expenditure|Lipid Metabolism|Fatty Acids|Triglycerides|Mitochondria|Disease Models, Animal|Myocardium|Liver 20 TONSL 21171993 Crit Care 2010 PMC3220025 10.1186/cc9377 8 3 2 109 Child|Humans|*Pneumococcal Disease|Streptococcus pneumoniae|*Study, Genetic Association|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies 28 TONSL 21113133 EMBO J. 2010 PMC3018799 10.1038/emboj.2010.304 27 3 3 109 Humans|*RNA Interference|Cullin 1|Cullin Proteins|DNA Replication|DNA-Binding Proteins|Nuclear Proteins|Histones|S Phase|Cell Cycle Proteins|Genomic Instability|Chromatin|NF-kappa B|DNA Damage|Saccharomyces cerevisiae|Recombination, Genetic|Protein Binding|Ubiquitin-Protein Ligases|HeLa Cells 28 TONSL 21055985 Mol. Cell 2010 PMC3006237 10.1016/j.molcel.2010.10.022 48 57 7 109 Humans|*Camptothecine|ATRIP protein, human|DNA-Binding Proteins|*Genomic Stability|DNA Repair|DNA Replication|Nuclear Proteins|Chromatin|NF-kappa B|Homologous Recombination|DNA Damage|DNA, Single-Stranded|Phosphorylation|Adaptor Proteins, Signal Transducing|Protein Binding|MMS22L protein, human 28 TONSL 21055984 Mol. Cell 2010 10.1016/j.molcel.2010.10.023 42 10 5 109 Humans|*Homologous Recombination|DNA Replication|Rad51 Recombinase|DNA Repair|DNA-Binding Proteins|Nuclear Proteins|Stability, Genome|S Phase|NF-kappa B|DNA Damage|Histones|Protein Binding|TONSL protein, human|MMS22L protein, human 28 TONSL 21055983 Mol. Cell 2010 PMC3031522 10.1016/j.molcel.2010.10.024 47 10 4 109 *Homologous Recombination|DNA Replication|DNA Repair|Rad51 Recombinase|DNA-Binding Proteins|DNA Breaks, Double-Stranded|DNA Damage|Nuclear Proteins|Genomic Instability|NF-kappa B|Histones|TOP1 protein, human|Topoisomerase I|Protein Binding|DNA, Single-Stranded 28 tppp3 20571904 Mol. Cell. Biochem. 2010 10.1007/s11010-010-0518-2 9 3 2 109 Humans|Animals|Mice|*Carcinoma, Lewis Lung|*RNA Interference|HeLa Cells|*Mice, Inbred C57BL|*Neoplastic Processes|Cell Proliferation|Lung Neoplasms|Cell Movement|Cell Line, Tumor|Cycles, Cell 22 TTC12 21168125 Biol. Psychiatry 2010 PMC3058144 10.1016/j.biopsych.2010.09.055 36 1 3 11 Humans|Adolescent|Adult|*Smoking Behavior|Tobacco Use Disorder|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Receptors, Nicotinic|Genetic Variation|Receptors, Dopamine D2|Gene Clusters|Nerve Tissue Proteins|CHRNA5 protein, human|CHRNB4 protein, human|TTC12 protein, human|Proteins|ANKK1 protein, human|Protein-Serine-Threonine Kinases|DRD2 protein, human 24 TTC12 20133381 Nicotine Tob. Res. 2010 PMC2825103 10.1093/ntr/ntp201 7 0 1 11 Humans|Female|Male|*Haplotypes|*White|*African Americans|Dependence, Nicotine|Linkage Disequilibrium|*Sex Differences|Polymorphism, Single Nucleotide|Genetic Variation|Smoking|*Smokers|Receptors, Dopamine D2|Protein-Serine-Threonine Kinases|Tobacco Smoking|TTC12 protein, human|Proteins|ANKK1 protein, human 24 WDFY4 20947545 Lupus 2010 10.1177/0961203310376639 6 0 1 12 Humans|*Lupus Erythematosus, Systemic|STAT4 Transcription Factor|Asian|Genetic Predisposition to Disease|*Lupus Erythematosus, Discoid|Genome-Wide Association Study|Polymorphism, Single Nucleotide|IRF5 protein, human|Interferon Regulatory Factors|European Continental Ancestry Group|*Genomics|Genetic Heterogeneity|Risk Factors|Asia 20 WDFY4 20169177 PLoS Genet. 2010 PMC2820522 10.1371/journal.pgen.1000841 141 9 8 12 Humans|*Genome-Wide Association Study|Leukocytes, Mononuclear|*Asian|*Lupus Erythematosus, Systemic|TNFSF4 protein, human|OX40 Ligand|TNFAIP3 protein, human|Tumor Necrosis Factor alpha-Induced Protein 3|Genetic Predisposition to Disease|Alleles|Polymorphism, Single Nucleotide|STAT4 Transcription Factor|Intracellular Signaling Peptides and Proteins|IRF5 protein, human|Interferon Regulatory Factors|Genotype|Nuclear Proteins|DNA-Binding Proteins 20 ZNF185 20937232 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010 0 0 0 64 Animals|Mice|Male|*Testis|*Cloning, Molecular|Spermatozoa|DNA-Binding Proteins|Amino Acid Sequence|Base Sequence|RNA, Messenger|ZNF185 protein, mouse|LIM Domain Proteins 24 ZNF644 20657603 Asian J. Androl. 2010 PMC3739317 10.1038/aja.2010.54 5 0 0 140 Male|Animals|Humans|*RING Finger Domains|*E3 Ubiquitin Ligase|*Testis|Ubiquitination|Spermatogenesis|Spermatids|Sperm Tail|HEK293 Cells|CBLL2 protein, human 20 ZNF91 20725991 Genes Chromosomes Cancer 2010 10.1002/gcc.20813 4 0 0 55 Humans|Female|*Chromosomes, Human, Pair 19|*Microdissections|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|Chromosome Aberrations|In Situ Hybridization, Fluorescence|Ovary|Cytogenetic|Chromosome Markers|Carcinomas 26 ABI3BP 19994723 Nagoya J Med Sci 2009 2 2 0 65 Humans|Mice|Animals|*Tumor Suppressor Protein p53|*Apoptosis|Senescence, Replicative|Cell Cycle|Carrier Proteins|Lung Neoplasms|RNAi|Fibroblasts|ABI3 protein, human|Adaptor Proteins, Signal Transducing|NESH protein, mouse 27 ABI3BP 19338757 Biochem. Biophys. Res. Commun. 2009 10.1016/j.bbrc.2009.01.171 8 1 0 65 Mice|Animals|*Tumor Suppressor Protein p53|*Cellular Senescence|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Cell Cycle|Cell Proliferation|GLB1 protein, human|beta-Galactosidase|Signal Transduction|shRNA|Fibroblasts|Lung Neoplasms|NESH protein, mouse|Adaptor Proteins, Signal Transducing 27 ABTB1 19930467 Genes Cells 2009 10.1111/j.1365-2443.2009.01358.x 2 3 0 20 Humans|*Cell Nucleus|*Cytoplasm|*Ubiquitylation|Nuclear Proteins|Yeast Two-Hybrid System|Repressor Proteins|Carrier Proteins|Transfection|Amino Acid Sequence|DNA Nucleotidylexotransferase|E3 Ligase|cDNA|HeLa Cells|Sequence Homology, Amino Acid 31 ACRV1 19931263 Gastroenterology 2009 PMC2831159 10.1053/j.gastro.2009.11.010 91 0 15 6 *Transcriptome|Prospective Studies|Retrospective Studies|Pancreatic Carcinoma|*Pancreatic Cancer|Biomarkers, Tumor|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|RNA, Messenger|Saliva|Sensitivity and Specificity|Proteomics|Case-Control Studies 57 ACRV1 19931263 Gastroenterology 2009 PMC2831159 10.1053/j.gastro.2009.11.010 91 0 15 6 *Transcriptome|Prospective Studies|Retrospective Studies|Pancreatic Carcinoma|*Pancreatic Cancer|Biomarkers, Tumor|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|RNA, Messenger|Saliva|Sensitivity and Specificity|Proteomics|Case-Control Studies 57 ACTBP2 19904551 Int. J. Legal Med. 2009 10.1007/s00414-009-0377-0 0 0 0 0 Male|Female|*Haplotypes|*Germ-Line Mutation|*Short Tandem Repeat|Paternity|Gene Frequency|Genetics, Population|Alleles|Mutation|Polymerase Chain Reaction 67 ACTBP2 19156434 Int. J. Legal Med. 2009 10.1007/s00414-008-0307-6 1 0 0 0 *Mutation Rate|Nigeria|*Frequencies, Allele|*Short Tandem Repeat|Genetics, Population|DNA Fingerprinting|Polymerase Chain Reaction|*Meiosis 67 ADAM7 19855936 Mol. Cells 2009 10.1007/s10059-009-0140-x 14 0 1 20 Male|Mice|Animals|Epididymis|Sperm Maturation|Sperm|*Cell Membrane|Integral Membrane Protein|Adam7 protein, mouse|ADAM Proteins 24 ADAM7 19435634 J Psychiatr Res 2009 10.1016/j.jpsychires.2009.04.006 13 1 1 20 Humans|*Schizophrenia|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|*Genetic Screening|Genotype|Genome-Wide Association Study|Case-Control Studies|*Cohort Studies|Asian Continental Ancestry Group|European Continental Ancestry Group|Alleles|Norway 24 ANKRD17 19619540 FEBS Lett. 2009 10.1016/j.febslet.2009.07.025 8 0 0 122 Mice|Animals|*Ankyrins|*Embryogenesis|Myocytes, Smooth Muscle|Muscle, Smooth, Vascular|Embryo, Mammalian|Cell Differentiation|Neovascularization, Physiologic|Gene Expression Regulation, Developmental|Gene Targeting|Transcriptional Activation|Up-Regulation 24 ANKRD17 19150984 J. Biol. Chem. 2009 PMC2658080 10.1074/jbc.M807827200 17 5 0 122 CCNE1 protein, human|*Cyclin E|CDK2 protein, human|*Cyclin-Dependent Kinase 2|S Phase|CDC2-CDC28 Kinases|Phosphorylation|Cyclin-Dependent Kinases|G1 Phase|DNA Replication|Nuclear Proteins|Cell Nucleus|PSMD10 protein, human|Proto-Oncogene Proteins|Chromatin|Cyclin-Dependent Kinase Inhibitor p27|Proteasome Endopeptidase Complex 24 BMP2K 19927351 J. Clin. Lab. Anal. 2009 PMC6649202 10.1002/jcla.20344 13 1 1 204 *Myopia|Genotype|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Restriction Fragment Length Polymorphism|Allele|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Case-Control Studies|Transforming Growth Factor beta|BMP2 protein, human 23 CDH22 19546606 Tumour Biol. 2009 10.1159/000225242 9 3 0 30 Mice|Animals|*Colorectal Carcinoma|Cadherins|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|mRNA|Biomarkers, Tumor|Lymphatic Metastasis|Colon|Cell Line, Tumor|*Colonic Neoplasms|Signal Transduction|*Neoplastic Processes|Cdh22 protein, mouse 26 CDH22 19440036 Cancer Biol. Ther. 2009 10.4161/cbt.8.14.8695 12 11 2 30 Mice|Animals|*Epithelial-Mesenchymal Transition|PTP4A3 protein, human|Mice, Nude|CDH1 protein, human|*E-Cadherin|Neoplasm Proteins|Protein Tyrosine Phosphatases|Snail Family Transcription Factors|Transcription Factors|Gene Expression Regulation, Neoplastic|Signal Transduction|Proto-Oncogene Proteins c-akt|Colorectal Cancer|Downregulation|Phosphorylation|Mesoderm|Cell Line, Tumor|Epithelial Cells 26 CDH22 19403372 Nan Fang Yi Ke Da Xue Xue Bao 2009 0 0 0 30 *Lentivirus|*RNA Interference|*Gene Knockdown Techniques|PTP4A3 protein, human|Protein Tyrosine Phosphatases|Neoplasm Proteins|*Colorectal Cancer|RNA, Small Interfering|Genetic Vectors|Transfection|Cell Line, Tumor|*Colonic Neoplasms|RNA, Messenger|*Protein Tyrosine Phosphatases, Non-Receptor 26 CDH22 19194496 PLoS ONE 2009 PMC2632748 10.1371/journal.pone.0004341 10 0 0 30 Animals|Mice|*Mice, Knockout|Cre recombinase|*Gene Targeting|Integrases|FLP recombinase|DNA Nucleotidyltransferases|Recombination, Genetic|Genetic Vectors|Alleles|Phenotype|Embryonic Stem Cells 26 CEND1 20002527 J. Neurochem. 2009 10.1111/j.1471-4159.2009.06536.x 4 2 0 30 Animals|Rats|*Neurogenesis|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|*Retinal Neurons|In Situ Hybridization|Membrane Proteins|Retina|Transcriptional Activation|POU5F1 protein, human|Octamer Transcription Factor-3|RNA, Messenger|Up-Regulation|cDNA 26 CEND1 19911428 Stem Cells 2009 10.1002/stem.258 14 1 2 30 Mice|Animals|*Embryonic Stem Cells|*Neurons|NES protein, human|Nestin|*Neural Stem Cells|Cell Differentiation|Stem Cell Transplantation|Glial Fibrillary Acidic Protein|Cells, Glial|Brain Injury|Cells, Cultured|Cell Movement|Disease Models, Animal|Astroglias|Recovery of Function|Cell Cycle|Cend1 protein, mouse|Membrane Proteins 26 CLIC6 19863549 Clin. Genet. 2009 10.1111/j.1399-0004.2009.01289.x 19 0 6 37 Humans|Comparative Genomic Hybridization|In Situ Hybridization, Fluorescence|Chromosome Deletion|Karyotyping|Chromosome Aberrations|Chromosome Breakage|Intellectual Disability|Phenotype|Oligonucleotide Array Sequence Analysis|Congenital Heart Defects 21 CLMN 20014094 Dev. Dyn. 2009 10.1002/dvdy.22171 0 0 0 48 Female|Animals|Rats|Pregnancy|*Tretinoin|*Brain|In Situ Hybridization|mRNA|Gene Expression Regulation, Developmental|Neurons|Vitamin A|Neuroblastoma|Embryonic Development|Downregulation 29 CRTAC1 19738042 Cancer Res. 2009 PMC2747722 10.1158/0008-5472.CAN-09-1752 26 4 1 35 Humans|*Neurofibromatosis 1|Glomus vagale tumors|*Glomus Tumor|Comparative Genomic Hybridization|Neurofibromin|Genes, Neurofibromatosis 1|Mitogen-Activated Protein Kinases|Genes, Tumor Suppressor|Signal Transduction|Toes|MAP Kinase Signaling System|Paraganglioma, Extra-Adrenal|CRTAC1 protein, human|Calcium-Binding Proteins 27 CYP4X1 19680825 Endocrine 2009 10.1007/s12020-009-9233-8 14 5 2 8 Humans|*Estrogen Receptor beta|*HEK293 Cells|estrogen receptor alpha, human|ERalpha|Estrogens|Cell Proliferation|Gene Expression Regulation, Neoplastic|Chromatin Immunoprecipitation|Cell Line, Tumor|Estradiol|Transcription, Genetic|Oligonucleotide Array Sequence Analysis|Protein Binding|Signal Transduction|Transcriptional Activation|Upregulation|Transfection 26 CYP4X1 19536296 PLoS ONE 2009 PMC2694267 10.1371/journal.pone.0005956 13 7 1 8 Animals|*Insertional Activation|*Chickens|*Transcriptional Activation|*Transgene|Genetic Vectors|Lentivirus|Insulator Elements|Locus Control Region|beta-Globins|Promoter Regions, Genetic|Virus Integration|Gene Therapy|Cell Line|Transcription Factors 26 DACH2 19896866 Trends Endocrinol. Metab. 2009 PMC2818438 10.1016/j.tem.2009.08.002 32 44 0 37 Humans|Male|Animals|Drosophila|Eye Proteins|Transcription Factors|Drosophila Proteins|Homeodomain Proteins|Retina|Nuclear Proteins|*Cell Transformation, Neoplastic|Gene Expression Regulation, Developmental|*Tumorigenesis|Mutation|Cell Differentiation|Organogenesis|Signal Transduction|Animals, Genetically Modified|Protein Binding|DACH1 protein, human|dachshund protein, Drosophila 36 DAZ3 20039973 Int. J. Androl. 2009 10.1111/j.1365-2605.2009.01015.x 15 0 3 1 Humans|Male|Deleted in Azoospermia 1 Protein|*Spermatogenesis|Oligozoospermia|Azoospermia|*Chinese|Chromosomes, Human, Y|Haplotypes|Infertility, Male|Sequence Tagged Sites|Genetic Loci|Genetic Predisposition to Disease|Gene Dosage|Gene Deletion|Phenotype|RNA-Binding Proteins|Genetic Testing 20 DAZ3 19223287 Hum. Reprod. 2009 10.1093/humrep/dep032 12 0 2 1 Male|Humans|*Testis|Deleted in Azoospermia 1 Protein|Chromosomes, Human, Y|Infertility, Male|Gene Deletion|Genetic Predisposition to Disease|Chromosome Deletion|Gene Dosage|RNA-Binding Proteins 20 DDX10 19332556 Mol. Cell. Biol. 2009 PMC2682003 10.1128/MCB.00029-09 33 0 3 68 Humans|nucleolin|*RNA-Binding Proteins|*Phosphoproteins|*Ribonucleoproteins|*Cell Nucleolus|Ribonucleoproteins, Small Nucleolar|Pre-rRNA|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|RNA, Small Nucleolar|18S RRNA|RNA Processing, Post-Transcriptional|Nuclear Proteins|RNA Helicase|Transcription, Genetic|RRP5 protein, S cerevisiae 29 DGCR6 20036641 Biochem. Biophys. Res. Commun. 2009 10.1016/j.bbrc.2009.12.120 4 4 0 67 Receptors, GABA-B|gamma-Aminobutyric Acid|Neurons|Signal Transduction|Protein Structure, Tertiary|Protein Binding|Hippocampus|Transfections|Cell Membrane|*22q11 Deletion Syndrome 24 DGCR6 19736351 Arch. Gen. Psychiatry 2009 PMC2958844 10.1001/archgenpsychiatry.2009.80 151 0 6 67 Child|Humans|*Intellectual Disability|*Autistic Disorder|Comparative Genomic Hybridization|DNA Copy Number Variations|*Schizophrenia|Developmental Disabilities|Gene Dosage|In Situ Hybridization, Fluorescence|Phenotype|*Databases, Genetic|Biological Products 24 DGCR6 19420922 Cytogenet. Genome Res. 2009 PMC2919456 10.1159/000207515 26 0 1 67 Humans|*DiGeorge Syndrome|Comparative Genomic Hybridization|DNA Copy Number Variations|*Chromosome Deletion|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Marfan Syndrome|*Craniosynostoses|Abnormalities, Multiple|Conotruncal cardiac defects|Heart Defects, Congenital|In Situ Hybridization, Fluorescence 24 DKKL1 19596312 Fertil. Steril. 2009 PMC2838937 10.1016/j.fertnstert.2009.06.010 9 0 0 98 Male|Mice|Animals|*Zona Pellucida|*Sperm Penetration|Acrosome|Spermatozoa|Fertility 22 DKKL1 19596310 Fertil. Steril. 2009 PMC2839020 10.1016/j.fertnstert.2009.06.011 4 5 1 98 Male|Animals|Mice|*Fertility|Spermatogenesis|Acrosome|RNA-Binding Proteins|Testis|Nuclear Proteins 22 DKKL1 19176879 Biol. Reprod. 2009 PMC2849823 10.1095/biolreprod.108.075382 31 2 2 98 Humans|Male|Female|Mice|Animals|*Spermatids|*Acetyltransferase, Histone|*Y-Linked Gene|Y Chromosome|Spermiogenesis|Testis|Sperm|Spermatocytes|Infertility, Male|Nuclear Proteins|Acrosome|Gene Expression Regulation|Adaptor Proteins, Signal Transducing|Fertility|Meiosis|Sly1 protein, human|Vesicular Transport Proteins|DKKL1 protein, human 22 DKKL1 19136570 J. Mol. Endocrinol. 2009 PMC2659293 10.1677/JME-08-0107 16 8 0 98 Male|Mice|Animals|*Testis|Sertoli Cells|Leydig Cells|Spermatogenesis|Follicle Stimulating Hormone|Testosterone|Hypogonadism|Androgens|Gonadotropin|RNA, Messenger|Organ Size|*Transcription, Genetic|Rhox5 protein, mouse|Transcription Factors|Homeodomain Proteins 22 DRAM2 19895784 Biochem. Biophys. Res. Commun. 2009 10.1016/j.bbrc.2009.10.149 13 4 1 31 Autophagy|Apoptosis|Lysosome|Tumor Suppressor Protein p53|Cell Line, Tumor|*Cell Death|Membrane Proteins|Amino Acid Sequence|Downregulation|Cell Survival|RNA Interference 21 EIF1AY 20031959 Eur. Heart J. 2009 PMC2869442 10.1093/eurheartj/ehp549 32 7 2 31 Humans|*Transcriptome|*Heart Failure|Cardiomyopathy, Dilated|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Myocardium|*Sex Factors|Biopsy 26 EIF1AY 19694371 Zhonghua Nan Ke Xue 2009 0 0 0 31 Male|Humans|*Azoospermia|*Testis|Oligonucleotide Array Sequence Analysis|Spermatogenesis|Gene Expression Profiling|In Situ Hybridization|*Inferior Colliculi|mRNA 26 EIF1AY 19605777 J. Child Neurol. 2009 10.1177/0883073809333530 9 0 0 31 Male|Humans|United States|*Haplotypes|*Autistic Disorder|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Y Chromosome|Cell Adhesion Molecules, Neuronal|Gene Frequency|Nerve Tissue Proteins|European Continental Ancestry Group|Membrane Proteins|Case-Control Studies 26 ENOSF1 19190136 Cancer Epidemiol. Biomarkers Prev. 2009 PMC2722075 10.1158/1055-9965.EPI-08-0831 2 1 0 12 Humans|Female|*Thymidylate Synthase|Case-Control Studies|*Chinese|Haplotype|Single Nucleotide Polymorphisms|*Endometrial Cancer|Genotype|Genetic Predisposition to Disease|Genetic Variation|Odds Ratio|Risk Factors|*Endometrium 23 EPB41L4B 19459069 Genomic Med 2009 PMC2694865 10.1007/s11568-009-9080-y 25 0 1 90 Humans|*Respiratory Syncytial Virus Infections|Respiratory Syncytial Viruses|*Epithelial Cell|Bronchi|Cell Line|Upregulation|Virus Replication|Signal Transduction|TUBB1 protein, human|Tubulin 23 EPB41L4B 19345106 Trends Cell Biol. 2009 PMC2796113 10.1016/j.tcb.2009.02.006 73 16 2 90 *Neurofibromin 2|*Signal Transduction|Cytoskeleton|Cytoskeletal Proteins|*Carrier Proteins|Cell Membrane|Actins|*Cytoplasm|*Biological Processes 23 EPB41L4B 19118189 J. Neurosci. 2009 PMC6671232 10.1523/JNEUROSCI.3112-08.2008 16 2 2 90 *PDZ Domains|*Dendritic Spines|*Postsynaptic Density Protein 95|radixin|Membrane Proteins|postsynaptic density proteins|Nerve Tissue Proteins|Synapses|Intracellular Signaling Peptides and Proteins|Dendrites|Neurons|Synaptic Membrane|Hippocampus|Rho Guanine Nucleotide Exchange Factors|Actins|moesin|Microfilament Proteins|*Transcription Factors 23 ERI3 19692710 Med Decis Making 2009 10.1177/0272989X09342747 7 0 2 23 *Early Detection of Cancer|Occult Blood|*Colorectal Neoplasms|Colonoscopy|Mass Screening|Attitude to Health|Surveys and Questionnaires|Probability 25 ERI3 19485980 Aliment. Pharmacol. Ther. 2009 10.1111/j.1365-2036.2009.04050.x 5 0 1 23 *Cohort Studies|*Asbestos|Mesothelioma, Malignant|Mesothelioma|*Occupational Exposure|Occupational Diseases|Lung Neoplasms|Peritoneal Neoplasms|Digestive System Neoplasms|*Gastrointestinal Neoplasms|Incidence 25 ERI3 19337253 Br. J. Cancer 2009 PMC2676539 10.1038/sj.bjc.6604996 10 0 1 23 *Guaiac|*Occult Blood|Colonoscopy|Adenomas|Colonic Polyps|Colorectal Cancer|Screening|*Colonic Diseases|Colonic Neoplasms|Feces|Indicators and Reagents|Predictive Value of Tests|Rectal Cancer 25 ETV3 19228815 J. Leukoc. Biol. 2009 PMC2669408 10.1189/jlb.0708448 18 2 0 1655 Humans|Mice|Animals|*Mast Cells|IL10 protein, human|*Interleukin-10|*Interleukin-4|*Mice, Inbred BALB C|Fc epsilon RI|Stem Cell Factor|STAT6 protein, human|STAT6 Transcription Factor|Interleukin-3|Bone Marrow Cells|Cytokines|Cell Differentiation|Proto-Oncogene Proteins c-kit|STAT3 protein, human|STAT3 Transcription Factor|Cells, Cultured|Macrophages 23 fibronogen 19770070 Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2009 10.1016/j.cbpc.2009.09.002 3 0 1 0 Humans|Cattle|Animals|Rabbits|Cats|Dogs|*Thrombin|*Trimeresurus|Kinetics|Fibrinogen|Crotalid Venoms|Fibrinopeptide A|Blood Coagulation|Hemostatics|Amino Acid Sequence|Gel Filtration Chromatography|Snake Venoms|Molecular Weight 23 FJX1 19401297 Hum. Mol. Genet. 2009 10.1093/hmg/ddp190 60 0 2 72 Mice|Animals|*Wnt Signaling Pathway|*Cell Polarity|Potter Type III Polycystic Kidney Disease|*Polycystic Kidney Diseases|Polycystic Kidney, Autosomal Dominant|*Kidneys|TRPP Cation Channels|Disease Models, Animal|Cell Proliferation 26 FOXJ3 19914232 Dev. Biol. 2009 PMC4540073 10.1016/j.ydbio.2009.11.015 0 12 2 127 Mice|Animals|*Muscle Fibers, Skeletal|Myogenesis|MyoD Protein|Muscle, Skeletal|Myoblasts|MEF2 Transcription Factors|Activation, Transcriptional|Binding Site|Cell Differentiation|Gene Expression Regulation, Developmental|Muscular Diseases|RNA Interference|Regeneration|Progenitor Cells|Base Sequence|RNA, Small Interfering|FoxJ3 protein, mouse|DNA-Binding Proteins 21 GAGE1 19287100 JOP 2009 0 0 0 20 Humans|Animals|Mice|Phosphatidylinositol 3-Kinases|*Pancreatic Cancer|gemcitabine|Deoxycytidine|Antimetabolites, Antineoplastic|Antineoplastic Combined Chemotherapy Protocols|Erlotinib|Protein Kinase Inhibitors|San Francisco 48 GBX1 19341460 Neural Dev 2009 PMC2674439 10.1186/1749-8104-4-12 10 3 0 17 34 GIMAP4 19421422 Exp Diabetes Res 2009 PMC2676327 10.1155/2009/835650 6 7 0 68 Rats|Animals|*Rats, Inbred BB|Diabetes Mellitus, Type 1|Lymphopenia|Chromosome Mapping|Alleles|GTP-Binding Proteins|Mutation, Frame Shift|Gimap5 protein, rat 29 glycolisis 19183005 J. Comput. Biol. 2009 10.1089/cmb.2008.21TT 3 0 1 0 *Biological Clocks|Circadian Rhythm|Computer Simulation|Oscillometry|Algorithm|Nerve Net|Models, Biological 23 GMFB 19787249 Int. J. Oncol. 2009 10.3892/ijo_00000410 5 0 1 125 Humans|Mice|Animals|Female|*Retroviridae|Genes, ras|Oncogenes|Gene Library|Cloning, Molecular|*Carcinogenesis|Cell Line|DNA, Complementary|Ovarian Cancer|3T3 Cells|Gene Expression|Codon|USP14 protein, human|Ubiquitin Thiolesterase 26 GPR26 19787267 Int. J. Oncol. 2009 10.3892/ijo_00000428 2 2 0 71 Adult|Humans|Animals|Rats|*Gliomas|Glioblastoma|Brain Neoplasms|Astrocytoma|Loss of Heterozygosity|PTEN protein, human|PTEN Phosphohydrolase|Genes, Tumor Suppressor|Mutation|Tumor Cells, Cultured|DMBT1 protein, human|Receptors, Cell Surface|GPRC5C protein, human|Receptors, G-Protein-Coupled|Gpr26 protein, rat 20 GPR85 19763624 Cell Tissue Res. 2009 10.1007/s00441-009-0859-x 21 0 3 29 Animals|Mice|*C57BL Mice|Trace amine-associated receptor 1|*G-Protein-Coupled Receptors|GPRC5A protein, human|GPRC5C protein, human|*Gastrointestinal Tract|mRNA|In Situ Hybridization|Systems, Enteric Nervous|Brain|Gpr37 protein, mouse|BAI2 protein, mouse|Membrane Proteins|Nerve Tissue Proteins|GPRC5A protein, mouse 25 GRIN3B 20016182 Dement Geriatr Cogn Disord 2009 10.1159/000254757 7 0 1 31 Humans|*Alzheimer Disease|*Receptors, N-Methyl-D-Aspartate|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*DNA Mutational Analysis|Gene Frequency|Risk Factors 21 GRIN3B 19737383 BMC Evol. Biol. 2009 PMC2753569 10.1186/1471-2148-9-224 3 4 0 31 Animals|Humans|*Amino Acid Substitution|Chimpanzee|Evolution, Molecular|Hominidae|Selection, Genetic|*Glutamate Receptor|Genome, Human|Species Specificity|Biological Evolution 21 HMGN3 19885867 J. Cell. Biochem. 2009 PMC3402347 10.1002/jcb.22377 5 5 0 72 Mice|Animals|*Pancreatic alpha Cell|*Glucagon|*Nucleosomes|*Binding Protein|HMGN3 protein, human|*HMGN Proteins|Islets of Langerhans|Insulin-Secreting Cells|Insulin Secretion|Insulin|Blood Glucose|Glucose|Homeostasis|HMGN3 protein, mouse 28 HMGN3 19651901 Mol. Cell. Biol. 2009 PMC2747976 10.1128/MCB.00526-09 20 2 0 72 Mice|Animals|*Insulin Secretion|*Insulin-Secreting Cells|*Nucleosomes|Diabetes Mellitus, Type 2|*Binding Protein|HMGN3 protein, human|*HMGN Proteins|B-insulin|Insulin|Glucose|Pancreatic Islets|Glucose Intolerance|Homeostasis|Transcription Factor|SLC2A2 protein, human|Biotin|GLUT2 Protein|HMGN3 protein, mouse 28 HMGN3 19138906 Yi Chuan 2009 10.3724/sp.j.1005.2009.00083 0 0 0 72 Animals|*Chickens|Beijing|Display, mRNA Differential|ESTs|*Pectoral Muscles|Sequences, Nucleotide|Muscle, Skeletal 28 HTATSF1 19966273 Nucleic Acids Res. 2009 PMC2831323 10.1093/nar/gkp1105 21 30 1 139 *Transactivator|rev Gene Products, Human Immunodeficiency Virus|tat Gene Products, Human Immunodeficiency Virus|*RNA Splicing|HIV-1|Gene Expression Regulation, Viral|Activation, Transcriptional|Transcription Factors|RNA, Viral|Promoter Regions, Genetic 26 HTATSF1 19479034 PLoS ONE 2009 PMC2682658 10.1371/journal.pone.0005710 11 9 2 139 Humans|*HIV-1|*Transcriptional Activation|HIV Long Terminal Repeat|tat Gene Products, Human Immunodeficiency Virus|*RNA Splicing|Virus Replication|Gene Expression Regulation, Viral|Transcription, Genetic|RNA, Viral|Trans-Activators|Transcription Factors|Promoter Regions, Genetic|Viral Proteins|HeLa Cells 26 hus1b 19833574 Curr. Biol. 2009 10.1016/j.cub.2009.07.026 0 3 0 18 *B-DNA|DNA Damage|DNA Repair|Exonucleases|Cell Cycle Proteins|xeroderma pigmentosum group F protein|DNA-Binding Proteins|Schizosaccharomyces pombe Proteins 32 hus1b 19615952 DNA Repair (Amst.) 2009 10.1016/j.dnarep.2009.06.004 0 15 0 18 Humans|8-hydroxyguanine|Hydrogen Peroxide|HEK293 Cells|oxoguanine glycosylase 1, human|*DNA Glycosylase|rad9 protein|Cell Cycle Proteins|DNA Repair|xeroderma pigmentosum group F protein|*DNA-Binding Proteins|Guanine|DNA Damage|Exonucleases|RRAD protein, human|*ras Proteins 32 hus1b 19535328 J. Biol. Chem. 2009 PMC2742809 10.1074/jbc.C109.022384 36 1 0 18 Humans|rad9 protein|Cell Cycle Proteins|xeroderma pigmentosum group F protein|*DNA-Binding Proteins|DNA Repair|Exonucleases|Proliferating Cell Nuclear Antigen|DNA Damage|Schizosaccharomyces pombe Proteins|*Cell Cycle Checkpoint|Binding Sites|RRAD protein, human|*ras Proteins 32 hus1b 19523882 DNA Repair (Amst.) 2009 PMC2759717 10.1016/j.dnarep.2009.05.002 11 20 1 18 Humans|*Proliferating Cell Nuclear Antigen|*DNA Ligase ATP|rad9 protein|*Cell Cycle Proteins|*DNA|DNA Ligases|DNA Replication|*Genes, cdc|Exonucleases|Nick, DNA|Cell Cycle|Protein Binding|*Protein Domains 32 hus1b 19464297 J. Mol. Biol. 2009 10.1016/j.jmb.2009.05.028 37 14 1 18 Humans|Base Excision Repair|DNA Damage|xeroderma pigmentosum group F protein|*DNA-Binding Proteins|Exonucleases|Cell Cycle Proteins|DNA|RRAD protein, human|*ras Proteins|Protein Structure, Secondary|Cell Nucleus 32 hus1b 19446481 Mol. Cell 2009 10.1016/j.molcel.2009.04.027 54 30 1 18 Humans|xeroderma pigmentosum group F protein|*DNA-Binding Proteins|DNA Repair|DNA Damage|Cell Cycle Proteins|Exonucleases|Schizosaccharomyces pombe Proteins|DNA Repair Enzymes|DNA|Protein Binding|Binding Site|RRAD protein, human|*ras Proteins|Signal Transduction 32 IGIP 20008019 J. Clin. Endocrinol. Metab. 2009 10.1210/jc.2009-2054 31 1 1 16 Humans|Male|*Incretins|*Glucose|*Gastric Inhibitory Polypeptide|DPP4 protein, human|*Dipeptidyl Peptidase IV|Glucagon-Like Peptide 1|*Obesity|*Ingestion|Glucagon|Insulin|Blood Glucose|*Meal|Diabetes Mellitus, Type 2 29 IGIP 19435824 J. Clin. Endocrinol. Metab. 2009 10.1210/jc.2009-0366 10 0 0 16 Humans|Male|*Incretins|*Gastric Inhibitory Polypeptide|*Meal|Insulin|Glucagon-Like Peptide 1|Glucagon|C-Peptide|Postprandial Period|Blood Glucose 29 IGIP 19201837 J. Immunol. 2009 PMC2878093 10.4049/jimmunol.0801973 9 22 1 16 Humans|*B Cells|Immunoglobulin Class Switching|TNFSF13B protein, human|B-Cell Activating Factor|Immunoglobulin A|Immunoglobulin D|Lymphocyte Activation|Dendritic Cells|sargramostim|Granulocyte-Macrophage Colony-Stimulating Factor|CD40 Ligand|Cell Differentiation|IgA-inducing protein, human|IL4 29 IGSF11 19671168 BMC Cancer 2009 PMC3224728 10.1186/1471-2407-9-279 13 10 1 18 Humans|*Transcription Factor|*Breast Cancer 2 Protein|Transcription Factor AP-2|Receptor, ErbB-2|Transcription, Genetic|Gene Expression Regulation, Neoplastic|Binding Sites|*Activating Transcription Factors|Cell Line, Tumor 27 IMPG1 19421330 PLoS ONE 2009 PMC2674219 10.1371/journal.pone.0005459 26 0 1 26 Humans|Rats|Animals|*Genome-Wide Association Study|Taiwan|*Asian Continental Ancestry Group|SNPs|Genetic Predisposition to Disease|*Hypertension|Case-Control Studies|Genotype 29 ITM2C 19139817 Invest New Drugs 2009 10.1007/s10637-008-9214-4 10 0 2 80 Animals|Mice|*Immunoconjugates|*Stomach Neoplasms|*Stomach|Radioimmunotherapy|Alpha Particles|Antibodies, Monoclonal|Peritoneal Carcinomatosis|Radioisotopes|Cell Line, Tumor|Nude Mouse|*Antineoplastic Agents|Downregulation|Upregulation|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Neoplasm Transplantation|Bismuth 27 KLK9 19953256 Mamm. Genome 2009 10.1007/s00335-009-9237-y 1 0 0 20 Humans|Dogs|Animals|Kallikrein|Splicings, Alternative|Exon|Intron|Mammary Neoplasms, Animal|Base Sequence|mRNA|Amino Acid Sequence|Open Reading Frames|*Cancer, Mammary|KLK10 protein, human 36 LSG1 20008552 Mol. Cell. Biol. 2009 PMC2815566 10.1128/MCB.01359-09 32 1 0 94 *Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|RNA, ribosomal, 25S|RNA, Fungal|5.8S RRNA|Pre-rRNA|Ribosomes|*Cytosol|RNA Processing, Post-Transcriptional|18S RRNA|Export, Nuclear|Cell Nucleolus|Cell Nucleus 26 LSG1 19144820 Mol. Biol. Cell 2009 PMC2649259 10.1091/mbc.E08-10-1000 9 0 1 94 *Ribosome|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|60S Ribosomal Subunit|Nucleocytoplasmic Transport Proteins|Active Transport, Cell Nucleus|Karyopherins|Nuclear Pore Complex|ran GTP-Binding Protein|Signal, Nuclear Export|RNA-Binding Proteins|Nuclear Proteins|Membrane Transport Proteins|Protein Binding|Los1 protein, S cerevisiae|Nuclear Pore Complex Proteins 26 METRN 19259827 J. Mol. Neurosci. 2009 10.1007/s12031-009-9189-4 12 0 2 47 Mice|Animals|enovin|*Nerve Growth Factors|NTF3 protein, human|Neurons|Nerve Tissue Proteins|Astrocytes|Central Nervous System|Dorsal Root Ganglion|Cells, Cultured|Cell Differentiation|Disease Models, Animal|Brain 22 METRN 19130216 Cell. Mol. Neurobiol. 2009 10.1007/s10571-008-9338-2 24 4 3 47 Humans|*Astrocytes|*Neural Stem Cells|ASCL1 protein, human|Basic Helix-Loop-Helix Transcription Factors|*Neurogenesis|*Gene Expression Profiling|Cell Differentiation|Neurons|Nestin|Transcription Factors|Upregulation|Glial Fibrillary Acidic Protein|Cells, Cultured|*Microarray Analysis|CSPG4 protein, human|Membrane Proteins|Cell Proliferation|Chondroitin Sulfate Proteoglycans 22 MTX3 19295654 Can. J. Microbiol. 2009 10.1139/w08-113 2 0 0 133 Animals|*Bacillus|binB protein, Bacillus sphaericus|Bacterial Toxins|Culex|Cloning, Molecular|Mosquito|Genes, Bacterial|*PCR, Multiplex|Escherichia coli|Larva|Insecticides 21 MTX3 19139435 J. Clin. Oncol. 2009 10.1200/JCO.2008.18.1487 31 0 0 133 Child|Adolescent|Humans|*Lymphoma, Large-Cell, Anaplastic|*Methotrexate|Lymphoma, Large B-Cell, Diffuse|Disease-Free Survival|Treatment Outcome|Antineoplastic Combined Chemotherapy Protocols 21 MYH15 19948655 J. Physiol. (Lond.) 2009 PMC2821527 10.1113/jphysiol.2009.181008 45 1 3 40 Rats|Mice|Animals|*Muscle Spindles|*Myosin B|*Oculomotor Muscles|*Skeletal Muscles|Myosin Heavy Chains|Sarcomeres|*Mammals|Myosin II|Isoforms|Gene Expression 24 MYH15 19752551 Cerebrovasc. Dis. 2009 PMC2818395 10.1159/000236914 11 0 1 40 Humans|*Coronary Heart Disease|*Stroke|Predispositions, Genetic|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|*Registry|Genotype|Odds Ratios|Risk Factors|Case-Control Studies|KIF6 protein, human|Kinesin 24 MYO5C 19741097 Mol. Biol. Cell 2009 PMC2770936 10.1091/mbc.E08-08-0865 27 0 2 604 Animals|*Secretory Vesicles|MYO5A protein, human|Myosin Type V|Myosin Heavy Chains|*Protein Transport|RAB8A protein, human|rab GTP-Binding Proteins|Myosins|Actin|Microtubule|*Cell Movement 22 MYO5C 19641326 Intervirology 2009 10.1159/000230669 7 1 2 604 *Actins|*Hep G2 Cells|Dengue Virus|Myosin Type V|Myosins|Cell Line|Protein Transport 22 NDFIP2 19343052 EMBO Rep. 2009 PMC2680872 10.1038/embor.2009.30 64 0 2 108 Humans|UBB protein, human|*Ubiquitin|Nedd4 Proteins|Ubiquitination|Endosomal Sorting Complexes Required for Transport|Ubiquitin-Protein Ligases|Membrane Proteins|Carrier Proteins|Amino Acid Motifs|Protein Binding|WW Domains|HEK293 Cells|NDFIP1 protein, human 24 NHLH1 20007355 J. Gen. Virol. 2009 10.1099/vir.0.017590-0 11 0 1 132 Humans|*Fatigue Syndrome, Chronic|Seroepidemiologic Studies|*Parvovirus B19, Human|Parvoviridae Infections|Erythema Infectiosum|Antibodies, Viral|Immunoglobulin M|ELISA|*Virus Diseases|DNA, Viral|Viral Nonstructural Proteins|*Fatigue|*Blood Group Antigens|Arthralgia|Parvovirus 43 PALMD 19895793 Biochem. Biophys. Res. Commun. 2009 10.1016/j.bbrc.2009.10.153 20 0 2 58 Humans|*Carcinoma, Hepatocellular|*Emodin|*Hep G2 Cells|Apoptosis|Cell Line, Tumor|G2 Phase Cell Cycle Checkpoints|Liver Neoplasms|Cyclin-Dependent Kinase Inhibitor p21|cDNA Microarray|Viability, Cell|Cell Cycle Checkpoints|Antineoplastic Agents|Signal Transduction|Gene Expression Regulation, Neoplastic 20 PCDH11Y 19859901 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009 10.1002/ajmg.b.31041 5 0 0 45 Animals|Adult|Humans|Alternative Splicing|Base Sequence|Exons|Introns|Amino Acid Sequence|RNA, Messenger|Sequence Analysis, DNA|Hominidae 24 PCDH11Y 19812029 Mol. Biol. Evol. 2009 10.1093/molbev/msp231 22 0 2 45 Male|Animals|Humans|*Gene Conversion|Y Chromosome, Human|Chromosomes, Human, X|Evolution, Molecular|Pan troglodytes|Phylogeny|Single Nucleotide Polymorphisms 24 PCDH11Y 19125367 Laterality 2009 10.1080/13576500802536439 5 0 0 45 Humans|Schizophrenia|Nerve Tissue Proteins|Handedness|*Phenotype|Membrane Proteins|Genetic Predisposition to Disease|Chromosome Mapping 24 PCDH11Y 19125366 Laterality 2009 10.1080/13576500802574984 7 0 0 45 Humans|Animals|Psychosis|Handedness|Chromosomes, Human, Y|Chromosomes, Human, X|Hominid|Models, Genetic|Brain|Language|Genetic Predisposition to Disease|Cognition|Cadherins 24 PDE3B signalling 19747167 Biochem. J. 2009 PMC2953723 10.1042/BJ20090842 17 59 1 0 Mice|Animals|*Insulin|CAV1 protein, human|*Caveolin 1|disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate|*Adipocyte|*Signal Transduction|*Dioxoles|3T3-L1|Phosphodiesterase 3B|Lipolysis|*Insulin, Regular, Human|cAMP Dependent Protein Kinase|Phosphorylation|Perilipin|Lipase, Hormone-Sensitive|Proto-Oncogene Proteins c-akt|*Adrenergic beta-Agonists|Caveolae 21 Pl15 19482071 Behav. Processes 2009 10.1016/j.beproc.2009.05.003 2 0 0 0 Male|Female|Animals|Humans|*Paternity|*Voles|Reproduction|Sexual Behavior, Animal|Microsatellite|Genotype|Father 23 Pl15 23765791 Environ Microbiol Rep 2009 10.1111/j.1758-2229.2009.00028.x 23 0 4 0 Swine|Male|Animals|*Bacillus cereus|cereulide|*Bacillus|Bacillus mycoides|Bacillus pseudomycoides|*Depsipeptides|Emetics|Food Microbiology|Bacillus thuringiensis|Multilocus Sequence Typing|Phylogeny|Genetic Variation 23 PLAC4 19892844 Clin. Chem. 2009 10.1373/clinchem.2009.132662 17 0 1 0 Humans|Female|Pregnancy|*Down Syndrome|*RNA|*Trisomy|*Alleles|*Single Nucleotide Polymorphism|Prenatal Diagnosis|Gene Frequency|Placenta|RNA, Messenger|Fetus|Case-Control Studies|Chromosome 21|Nucleotides 22 PLAC4 19516908 PLoS ONE 2009 PMC2690655 10.1371/journal.pone.0005858 9 0 1 0 Pregnancy|Female|Humans|*mRNA|Placenta|Fetus|Prenatal Diagnosis 22 POU6F1 19874398 Hum. Cell 2009 10.1111/j.1749-0774.2009.00074.x 0 0 0 30 Humans|Female|*Adenocarcinoma, Clear Cell|*Ovary|*Transcription Factor|*Cell Proliferation|Ovarian Cancer|Cell Line, Tumor|RNA Interference|siRNA|Gene Expression Regulation, Neoplastic|Anticancer Agents|Carcinoma, Ovarian Epithelial 34 POU6F1 19450691 J. Struct. Biol. 2009 10.1016/j.jsb.2009.05.003 4 0 1 30 Humans|*Promoter Regions, Genetic|POU Domain Factors|CEBPB protein, human|*CCAAT-Enhancer-Binding Protein-beta|Homeodomain Proteins|DNA|Amino Acid Sequence 34 PTPRCAP 20019842 Neoplasia 2009 PMC2794515 10.1593/neo.91132 8 0 1 34 Humans|*Stomach Neoplasms|Case-Control Studies|Haplotypes|Single Nucleotide Polymorphism|Linkage Disequilibrium|Genetic Predisposition to Disease|Allele|Gene Frequency|*Gene Expression|Promoter Regions, Genetic|Genotype|Homozygote|Odds Ratio 48 PTPRCAP 19797129 Eur. Respir. J. 2009 PMC2862896 10.1183/09031936.00085509 2 22 0 34 Mice|Animals|*Neutrophils|*Lipopolysaccharides|*Phosphatidylinositol 3-Kinases|*Phosphoinositide 3 Kinase|Endothelial Cells|*Lung|PIK3CG protein, human|Class Ib Phosphatidylinositol 3-Kinase|Transendothelial Migration|*Cell Movement|Bronchoalveolar Lavage Fluid|Mice, Inbred C57BL|Mice, Knockout|Chemokines 48 PYHIN1 19762380 Lupus 2009 10.1177/0961203309106699 26 0 0 57 Humans|Mice|Animals|*Reverse Transcriptase Polymerase Chain Reaction|*Leukocytes|*Real Time PCR|Up-Regulation|Gene Expressions|Antibodies, Antinuclear|Isoforms|Genes, cdc|Biopsy 20 RAPGEF6 19176753 Mol. Biol. Cell 2009 PMC2663925 10.1091/mbc.E08-10-1014 74 17 3 96 *Integrin beta1|afadin|*Junctional Adhesion Molecule A|*Junctional Adhesion Molecule B|RAP1A protein, human|*rap1 GTP-Binding Proteins|F11R protein, human|*Cell Adhesion Molecules|*Microfilament Proteins|*Receptors, Cell Surface|*Cell Migration|Tight Junction|Guanine Nucleotide Exchange Factor|Cell Adhesion|Signal Transduction|Membrane Proteins|Cells, Epithelial|Immunoglobulin 25 RAX2 19135436 Dev. Biol. 2009 10.1016/j.ydbio.2008.12.017 5 0 0 14 Animals|*Xenopus laevis|*Photoreceptor Cell|Genes, Homeobox|*Cell Differentiation|Xenopus Proteins|Homeodomain Proteins|Retina|Transcription Factors|Eye Proteins|Gene Expression Regulation, Developmental|Progenitor Cells|In Situ Hybridization 25 RIMS2 19199833 Biol. Chem. 2009 10.1515/BC.2009.041 13 3 3 81 Humans|*Tight Junctions|*Synaptic Membranes|TJP1 protein, human|*Zonula Occludens-1 Protein|SCRIB protein, human|Viral Nonstructural Proteins|Tick-Borne Encephalitis Virus|Tumor Suppressor Proteins|Phosphoproteins|Plasma Membrane|Cell Nucleus|Interferon|*Membrane|Transcription Factors|Cell Line|*Exocytosis 35 RNF39 19693088 Genes Immun. 2009 PMC2873233 10.1038/gene.2009.58 12 0 0 8 Humans|*HLA-C|*Haplotypes|Genome-Wide Association Study|HLA-B|HIV-1|HIV Infections|Viral Load|Alleles|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Disease Progression|RNF39 protein, human|Immediate-Early Proteins 22 SBSN 19441785 Inorg Chem 2009 10.1021/ic900496p 0 0 0 57 Crystallography, X-Ray|X-Ray Diffraction|Models, Molecular 23 SCAMP2 19563849 Peptides 2009 PMC2755607 10.1016/j.peptides.2009.06.021 0 28 0 316 Mice|Humans|Animals|procolipase|*Insulin Secretion|*Insulin-Secreting Cells|*Colipases|*Enzyme Precursors|Insulin|*Protein Transport|Protein Precursors|Insulinoma|Glucose|Carrier Proteins|F1-ATPase|Blotting, Western|Biological Transport|Cell Line|Pancreatic Neoplasms 26 SCAMP2 19545450 BMC Neurosci 2009 PMC2716352 10.1186/1471-2202-10-65 25 16 0 316 *Norepinephrine Plasma Membrane Transport Proteins|*Antidepressive Agents|Norepinephrine|Neurons|Protein Transport|Nerve Tissue Proteins|Cells, Cultured|Biological Transport 26 SCAMP2 19438519 Cell. Microbiol. 2009 PMC2730479 10.1111/j.1462-5822.2009.01329.x 29 15 2 316 Humans|HeLa Cells|Salmonella Infections|Salmonella typhimurium|*Golgi Apparatus|Vacuoles|*Protein Transport|Salmonella enterica|Endosomes|trans Golgi Network|Bacterial Proteins|Cells, Epithelial|Host-Pathogen Interactions|Biological Transport|SCAMP3 protein, human|Carrier Proteins|Membrane Proteins 26 SCAMP2 19376937 Plant Cell 2009 PMC2685622 10.1105/tpc.108.058933 46 1 4 316 Animals|*Secretory Vesicles|*Plant Cells|*Golgi Apparatus|Tobacco|trans Golgi Network|Rice|Plant Proteins|Plasma Membrane|Protein Transport|Secretory Pathway|Organelles 26 SCAMP2 19276089 J. Biol. Chem. 2009 PMC2679489 10.1074/jbc.M807055200 0 7 1 316 Animals|Cricetinae|*Sodium-Hydrogen Exchangers|*Plasma Membrane|Endosomes|Integral Membrane Proteins|Protein Transport|*Brain|ADP-ribosylation factor 6|ADP-Ribosylation Factors|Membrane Transport Proteins|Neurons|Biological Transport|Signal Transduction|CHO Cells 26 SCRN1 20039278 J Surg Oncol 2009 10.1002/jso.21459 12 0 1 65 *Colorectal Cancer|*Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gastric Cancer|*Colonic Neoplasms|Antigens, Neoplasm|Upregulation|Cell Line, Tumor 21 SCRN1 19864314 Biol. Reprod. 2009 PMC2809227 10.1095/biolreprod.109.079822 21 0 1 65 Male|Female|Mice|Animals|Gene Regulatory Networks|*Gonads|*Sex Differentiation|Sertoli Cells|*Cell Differentiation|Sex Determination Processes|Gene Chip|Testis|Transgenic Mouse|Ovary|Granulosa Cells|Transcription Factors|Disorders of Sex Development|Gene Expression Profiling|Gene Expression Regulation, Developmental|Sexual Dimorphisms|granulose|*Polysaccharides 21 SHROOM2 19554350 Dev. Genes Evol. 2009 PMC2902998 10.1007/s00427-009-0292-x 3 18 0 47 Animals|*Spectrin|Xenopus laevis|Xenopus Proteins|Oogenesis|Oocytes|*Pigmentation|*Actin Cytoskeleton|gamma-Tubulin|Dynactin|Zygotes|Blastomeres|Messenger RNA 26 SHROOM2 19384856 Dev. Dyn. 2009 PMC2699254 10.1002/dvdy.21942 20 1 1 47 Animals|Xenopus laevis|*Morphogenesis|Xenopus Proteins|Epithelium|Cells, Epithelial|Embryo, Nonmammalian|Microfilament Proteins|Gene Expression Regulation, Developmental|In Situ Hybridization|Oocytes|mRNA 26 SPANXA1 20010347 Dis. Colon Rectum 2009 10.1007/DCR.0b013e3181bdca3a 13 0 3 37 Male|*Risk Factors|*Testis|*Colorectal Cancer|*Liver Neoplasms|Biomarkers, Tumor|*Colonic Neoplasms|Lymphatic Metastasis|Logistic Models 27 SPANXA1 19318807 Am J Dermatopathol 2009 10.1097/DAD.0b013e3181978d6f 3 0 0 37 Humans|Male|Nevi|Melanoma|Skin Neoplasms|Nevus, Epithelioid and Spindle Cell|Immunohistochemistry|Nuclear Proteins|Testicular Germ Cell Tumor|Testicular Neoplasms|Skin|Spermatozoa|Neoplasms, Germ Cell and Embryonal 27 STK17B 19638987 Br. J. Cancer 2009 PMC2720240 10.1038/sj.bjc.6605144 11 19 0 215 *Cyclooxygenase 2|*Colorectal Cancer|Apoptosis|Dinoprostone|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Cell Line, Tumor|Cyclooxygenase 2 Inhibitors|*Cell Death 32 STOML1 19900269 Arthritis Res. Ther. 2009 PMC3003511 10.1186/ar2855 19 2 1 71 Humans|*Transcriptome|*Spondyloarthropathy|*Spondylarthritis|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling 20 STOML1 19696025 J. Biol. Chem. 2009 PMC2781465 10.1074/jbc.M109.014993 15 1 1 71 Humans|*Endosomes|sterol carrier proteins|Carrier Proteins|Membrane Protein|Plasma Membrane|Protein Structure, Tertiary|Amino Acid Sequence|Protein Transport|Cholesterol|*Synapsins|Biological Transport 20 SVOP 19390693 PLoS ONE 2009 PMC2669215 10.1371/journal.pone.0005315 9 9 0 115 Humans|*Binding Protein|*Nucleotides|Adenosine Triphosphate|Binding Sites|Guanosine Triphosphate|Membrane Glycoproteins|Synaptic Vesicle|Biological Transport|Active Transport 26 TBPL1 19515240 BMC Biochem. 2009 PMC2702275 10.1186/1471-2091-10-16 3 47 1 1191 GMNN protein, human|*Geminin|Transcription Factors|*Gene Expression Regulation|Transcription, Genetic|Nuclear Proteins|TATA-Box Binding Protein|Promoter Regions, Genetic|Proteins, Homeo Domain|Protein Binding|Polycomb-Group Proteins|Amino Acid Sequence 28 TBPL1 19369647 Biol. Reprod. 2009 PMC2849822 10.1095/biolreprod.109.076000 1 0 0 1191 Male|Humans|Mice|Animals|*Amino Acid Substitution|*Infertility, Male|Azoospermia, Nonobstructive|Azoospermia|Oligospermia|Single Nucleotide Polymorphisms|Fertility|Mutation|Sperm|Heterozygote|Cytogenetic Abnormalities|TBPL1 protein, human|TATA Box Binding Protein-Like Proteins|LIMK2 protein, human|Lim Kinases 28 TCF15 19419955 J. Biol. Chem. 2009 PMC2709394 10.1074/jbc.M109.007096 32 21 2 58 *Transforming Growth Factor beta|*Acetylation|SMAD2 protein, human|Smad2 Protein|SMAD4 protein, human|Smad4 Protein|Smad3 Protein|*Cells, Epithelial|Promoter Regions, Genetic|p300-CBP Transcription Factors|Kruppel-Like Transcription Factors|Transcription, Genetic|Signal Transduction|Protein Binding|Transforming Growth Factors 39 TEX19 19247806 Mol. Biol. Rep. 2009 10.1007/s11033-009-9470-1 8 1 2 48 Male|Animals|Mice|*3' Untranslated Regions|*mRNA|DAZL protein, mouse|RNA-Binding Proteins|Germ Cells|Protein Biosynthesis|Spermatogenesis|Binding Sites|Base Sequence|Zebrafish|Transcription Factors|Testis|Electrophoretic Mobility Shift Assay|Tex19 protein, mouse|Nuclear Proteins 20 TLE6 19454485 Hum. Mol. Genet. 2009 PMC2708134 10.1093/hmg/ddp229 13 0 1 17 *Linkage Disequilibrium|*Pedigree|*Autistic Disorder|Finland|*Genetic Linkage|Chromosome Mapping|Alleles|Microsatellite Marker|Haplotypes|Genotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Family Health 23 TTC12 19796663 Prog. Neuropsychopharmacol. Biol. Psychiatry 2009 10.1016/j.pnpbp.2009.08.024 8 3 0 11 Humans|*Growth Hormone|*Apomorphine|*Alcoholism|Pilot Projects|*Genotypes|Genetic Predisposition to Disease|*Human Growth Hormone|Polymorphism, Single Nucleotide|Receptors, Dopamine D2|*Pituitary Hormones, Anterior|*Ethanol|*Drug Hypersensitivity|Protein-Serine-Threonine Kinases|Case-Control Studies|ANKK1 protein, human|DRD2 protein, human 24 ZNF185 19284880 BMC Genomics 2009 PMC2664823 10.1186/1471-2164-10-109 5 0 0 64 Humans|*Expressed Sequence Tag|*Pituitary Gland|*Pituitary Diseases|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Developmental|Transcription Factors|RNA, Messenger|Signal Transduction 24 ABTB1 18459963 Genes Cells 2008 10.1111/j.1365-2443.2008.01191.x 9 5 1 20 Humans|Animals|Rabbits|*Eukaryotes|*Ubiquitylation|EEF1A1 protein, human|*Peptide Elongation Factor 1|Yeast Two-Hybrid System|Cytoplasm|Proteasome Endopeptidase Complex|parkin protein|Ubiquitin-Protein Ligases|Binding Protein|*Eukaryotic Cells|Repressor Proteins|Protein Binding|Immunoprecipitation|Cell Line|Adaptor Proteins, Signal Transducing 31 ABTB1 18429817 Genes Cells 2008 10.1111/j.1365-2443.2008.01179.x 4 3 1 20 Humans|*DNA Nucleotidylexotransferase|*Saccharomyces cerevisiae|ATP dependent 26S protease|Proteasome Endopeptidase Complex|Yeast Two-Hybrid System|*Yeast, Dried|Ubiquitin|Ubiquitination|Nuclear Proteins|Cullin Proteins|Binding Protein|E3 Ligase|Cell Nucleus|Repressor Proteins|DNA-Binding Proteins|Cytoplasm|*DNA-Directed DNA Polymerase|HeLa Cells 31 ACRV1 18479850 Anim. Reprod. Sci. 2008 10.1016/j.anireprosci.2008.04.005 2 0 0 6 Animals|Humans|Male|Sperm Motility|*Goat|*Frozen Semen|*Spermatozoa|Acrosome|Cryopreservation|Semen|Semen Analysis|Freezing|Cell Survival|Cell Membrane 57 ACRV1 18340633 Proteomics 2008 10.1002/pmic.200701020 37 0 4 6 Male|Mice|Animals|*Proteome|*Chromatography, Liquid|Proteomics|*Tandem Mass Spectrometry|Electrophoresis, Gel, Two-Dimensional|*Sperm|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|zonadhesin|Membrane Proteins|Gene Expression Profiling|SPESP1 protein, mouse|Carrier Proteins|Seminal Plasma Proteins|ACRBP protein, mouse|Acrosome|Odf1 protein, mouse|Heat-Shock Proteins 57 ACRV1 18479850 Anim. Reprod. Sci. 2008 10.1016/j.anireprosci.2008.04.005 2 0 0 6 Animals|Humans|Male|Sperm Motility|*Goat|*Frozen Semen|*Spermatozoa|Acrosome|Cryopreservation|Semen|Semen Analysis|Freezing|Cell Survival|Cell Membrane 57 ACRV1 18340633 Proteomics 2008 10.1002/pmic.200701020 37 0 4 6 Male|Mice|Animals|*Proteome|*Chromatography, Liquid|Proteomics|*Tandem Mass Spectrometry|Electrophoresis, Gel, Two-Dimensional|*Sperm|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|zonadhesin|Membrane Proteins|Gene Expression Profiling|SPESP1 protein, mouse|Carrier Proteins|Seminal Plasma Proteins|ACRBP protein, mouse|Acrosome|Odf1 protein, mouse|Heat-Shock Proteins 57 ACTBP2 18325051 BJU Int. 2008 10.1111/j.1464-410X.2008.07591.x 10 0 1 0 *Bayes Theorem|Neoplasm Recurrence, Local|*Carcinoma, Transitional Cell|*Urinary Bladder Neoplasms|*Urinalysis|*Microsatellite Markers|Loss of Heterozygosity|Biomarkers, Tumor|Bladder|DNA Methylation|Markers, DNA 67 ACTBP2 19291455 Forensic Sci Med Pathol 2008 10.1007/s12024-007-9021-9 0 0 0 0 *Alleles|Gene Frequency|DNA Fingerprinting|Polymorphism, Genetic|Genetic Variation|Tandem Repeat Sequences|Pseudogenes|Polymerase Chain Reaction|Sequence Analysis, DNA|5' Flanking Region 67 ADAM7 18355041 Biochemistry 2008 10.1021/bi702447u 3 5 0 20 Humans|*Cell Adhesion|*Disintegrins|*trans Retinoic Acid|*Integrins|Jurkat Cells|9-cis-Retinoic Acid 24 AGAP1 18809720 J. Cell Biol. 2008 PMC2542466 10.1083/jcb.200806041 63 10 2 202 Humans|*Consensus|GTPase-Activating Proteins|ADP-Ribosylation Factors|Adaptor Proteins, Signal Transducing|Cell Cycle Proteins|Amino Acid Sequence|Italy 25 ATL2 18270207 Hum. Mol. Genet. 2008 PMC2902292 10.1093/hmg/ddn046 78 3 7 95 Humans|*GTPases|HeLa Cells|*Golgi Apparatus|*Endoplasmic Reticulum|Spastic paraplegia 3, autosomal dominant|Spastic Paraplegias, Hereditary|Spastin|GTP-Binding Proteins|Protein Transport|Membrane Proteins|Adenosine Triphosphatases|G protein, vesicular stomatitis virus|Membrane Glycoproteins|*Morphogenesis|Motor Neurons|Viral Envelope Proteins 23 BARHL1 18668008 Med. Sci. Monit. 2008 0 0 0 73 Humans|Animals|Quality of Life|Retrospective Studies|*Hearing Loss, Sensorineural|*Stem Cell Transplantation|Hair Cells, Auditory|Ear, Inner|Stem Cells|Regeneration|Cell Differentiation|*Hematopoietic Stem Cell Transplantation|Hearing Impairment|Epithelium|Case-Control Studies 35 BMP2K 18976975 Cell Host Microbe 2008 10.1016/j.chom.2008.10.004 399 4 22 204 Humans|*RNA Interference|Human immunodeficiency virus 1|Virus Replication|siRNA|HIV Infections|Host-Pathogen Interactions|mRNA|HeLa Cells 23 CDC42EP4 18398573 J. Neurooncol. 2008 10.1007/s11060-008-9579-4 38 0 1 127 Humans|*Glioblastoma|*Oligonucleotide Array Sequence Analysis|*Transcriptome|*Real-Time PCR, Quantitative|Brain Neoplasms|*Brain|Gene Expression Profiling|STIM1 protein, human|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Immunohistochemistry|Prognosis|cDNA|Stromal Interaction Molecule 1|EEF1A1 protein, human|Peptide Elongation Factor 1|EMP3 protein, human 20 CDH19 18364357 J. Biol. Chem. 2008 PMC2386911 10.1074/jbc.M802139200 77 5 9 36 Humans|CCL2 protein, human|*Monocyte Chemotactic Protein-1|*Transcription Factor|*Monocytes|*Gene Expression Regulation|Ribonucleases|RNA, Small Interfering|Autophagy|Human Umbilical Vein Endothelial Cells|Cell Line 25 CDH22 18602983 Genomics 2008 PMC2583938 10.1016/j.ygeno.2008.06.004 16 1 0 30 Humans|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|SNPs|Diabetic Nephropathies|European Continental Ancestry Group|Genetic Predisposition to Disease|End Stage Renal Disease|Case-Control Studies|Linkage Disequilibrium|Haplotype|African Americans|Genotype|*Human Chromosome|Cohort Studies|PREX1 protein, human|Guanine Nucleotide Exchange Factors|ELMO2 protein, human|Cytoskeletal Proteins 26 CDH22 18495598 Nan Fang Yi Ke Da Xue Xue Bao 2008 0 0 0 30 Humans|*RNA Interference|Lentivirus|RNA, Small Interfering|*Gene Silencing|Genetic Vectors|Transfection|Cell Line, Tumor|RNA, Messenger|Colorectal Cancer|CDH22 protein, human|Cadherins 26 CDH22 18196597 Genesis 2008 10.1002/dvg.20344 3 0 0 30 Animals|Mice|Cre recombinase|*Hindbrain|*Mesencephalon|Integrases|Transgenic Mouse|*Cell Differentiation|Brain|Transcription Factors|Gene Expression Regulation, Developmental|*Cells, Cultured|Cdh22 protein, mouse|Cadherins 26 CDKL2 18395440 J. Steroid Biochem. Mol. Biol. 2008 10.1016/j.jsbmb.2008.02.009 4 7 0 100 Rats|Animals|*Receptors, Glucocorticoid|*Glucocorticoids|*Melatonin|Amyloid beta-Peptides|*Cell Proliferation|*Hippocampus|Dexamethasone|Cell Cycle|Neurogenesis|Cyclin-Dependent Kinase Inhibitor p21|Cell Nucleus|*Protein Transport|Glutamate 20 CEND1 19061903 Neuropharmacology 2008 10.1016/j.neuropharm.2008.10.015 2 3 0 30 Mice|Humans|Animals|HeLa Cells|Cell Differentiation|Nerve Tissue Proteins|Neurons|Cell Cycle|Neurogenesis|Nervous System|Cell Proliferation|Membrane Proteins|Calcium Signaling|Endoplasmic Reticulum|Cell Line, Tumor|Mitochondria|Cend1 protein, mouse 26 CEND1 18499894 Stem Cells 2008 10.1634/stemcells.2007-0921 14 1 1 30 Animals|*Lateral Ventricles|*Neural Stem Cells|*Cell Differentiation|Neurogenesis|Neurons|*Nervous System|Nerve Tissue Proteins|Olfactory Bulb|Cell Cycle|Membrane Proteins|Cell Proliferation 26 CEND1 18258204 FEBS Lett. 2008 10.1016/j.febslet.2008.01.052 8 3 0 30 *Histone Deacetylase Inhibitors|*Cell Differentiation|trichostatin A|Hydroxamic Acids|Cell Cycle|Histone Deacetylases|Cell Proliferation|Neuroblastoma|Cell Line, Tumor|*Neural Stem Cells|Nerve Tissue Proteins|Gene Expression Regulation, Neoplastic|Neurons 26 CEND1 18239460 Cell Cycle 2008 10.4161/cc.7.6.5550 17 0 1 30 *Cell Differentiation|*Cell Cycle|*Neurons|Nerve Tissue Proteins|Progenitor Cell|Neurogenesis|Membrane Proteins|*Cell Division 26 CLIC6 18629192 Comp. Funct. Genomics 2008 PMC2447486 10.1002/cfg.476 6 0 0 37 Humans|Cattle|Animals|Mice|Contig Mapping|Chromosome Mapping|*Human Chromosome|Chromosomes, Artificial, Bacterial|Gene Library|Chromosomes, Bacterial|Genomics|Microsatellite Markers|Synteny|Chromosome Walking|Gene Order|cDNA 21 CLIC6 18536934 Pflugers Arch. 2008 PMC3079481 10.1007/s00424-008-0495-4 50 1 3 37 *ATPase|Gastric H(+) K(+) ATPase|*Stomach|Binding Site|Protein Conformation|Models, Molecular|Proton Pump Inhibitors|Subunit, Catalytic|Potassium|Mutagenesis, Site-Directed|Mutagenesis|Ion Transport|Protein Transport 21 CLIC6 18487507 Blood 2008 PMC2515126 10.1182/blood-2008-01-135970 19 0 4 37 Humans|Child|Comparative Genomic Hybridization|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|*Leukemia, Myeloid, Acute|*Thrombocytopenia|*Genotype|Hematopoiesis|Mutation|*Leukopenia|Genetic Predisposition to Disease|*Chromosome 21 CLIC6 18321301 Helicobacter 2008 10.1111/j.1523-5378.2008.00584.x 9 0 0 37 *Helicobacter pylori|Helicobacter Infections|*Pyloric Antrum|Gastric Mucosa|Gastritis|Stomach Neoplasms|*Gene Expression|CXCL13 protein, human|*Chemokine CXCL13|Stomach Ulcer 21 CLMN 18290675 Anal. Chem. 2008 10.1021/ac702476p 5 0 0 48 *Fourier Analysis|*Cyclotrons|Gas Chromatography-Mass Spectrometry|*Laser|Molecular Weight|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|*Acoustic|*Oils 29 CPA6 18234543 Oral Oncol. 2008 10.1016/j.oraloncology.2007.10.011 11 0 0 44 Humans|*Carcinoma, Squamous Cell|*Mouth Neoplasms|*Pilot Projects|dimethylaniline monooxygenase (N-oxide forming)|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Upregulation|Gene Expression|LGI1 protein, human|Proteins 24 CPA6 18178555 J. Biol. Chem. 2008 10.1074/jbc.M707680200 18 0 1 44 Animals|Humans|Mice|carboxypeptidase A6, human|Carboxypeptidases A|Duane Syndrome|*Peptide Hydrolases|Substrate Specificity|Abducens Nerve|Amino Acid Sequence|Peptides|Proteins|*Extracellular Matrix|Brain 24 CRYZ 19007775 Exp. Eye Res. 2008 10.1016/j.exer.2008.10.011 110 3 6 488 Humans|Male|Animals|Guinea Pigs|*Cataract|beta-crystallin B2|beta-Crystallin B Chain|gamma-Crystallins|DNA Mutational Analysis|Lens, Eye|Mutations|Exons|Amino Acid Sequence|Chromosomes|Heat-Shock Proteins, Small|Polymerase Chain Reaction|CRYBB1 protein, human|CRYBA1 protein, human|beta-Crystallin A Chain|CRYBB3 protein, human 164 CST8 18391548 Sex Dev 2008 10.1159/000111768 3 0 0 190 Male|Female|Mice|Animals|Testis|Epididymis|*Cystatins|*Reproduction|Sertoli Cells|*Gonads|Sex Differentiation|In Situ Hybridization|Amino Acid Sequence|DNA, Complementary|Fertility|Ovary|Mice, Knockout|Gene Expression|RNA, Messenger 31 CYP4X1 18549450 FEBS J. 2008 PMC4765179 10.1111/j.1742-4658.2008.06518.x 0 10 0 8 Humans|Male|anandamide|*Endocannabinoids|Escherichia coli|*Arachidonic Acids|*Polyunsaturated Alkamides|cytochrome P-450 4X1|*Cytochrome P-450 Enzyme System|*Oxidation-Reduction|Arachidonic Acid|8,11,14-Eicosatrienoic Acid|Amino Acid Sequence 26 DACH2 19109424 Mol. Biol. Cell 2008 PMC2642751 10.1091/mbc.E08-07-0759 48 3 3 37 *Myogenin|HDAC4 protein, human|*Histone Deacetylases|*Repressor Proteins|Muscle Denervation|*Gene Expression|Myocyte Enhancer Factor 2|Gene Expression Regulation|Nuclear Proteins|Muscle, Skeletal|Neuromuscular Junction|Signal Transduction|Nicotinic Acetylcholine Receptor|Neurons 36 DACH2 18395837 Genesis 2008 10.1002/dvg.20385 10 0 0 37 Male|Female|Animals|Mice|Drosophila|DNA-Binding Proteins|Nuclear Proteins|Transcription Factors|Eyes|Eye Proteins|Wolffian Duct|Gene Expression Regulation, Developmental|WNT7A protein, human|Wnt Proteins|Phenotype|Limbs|Vertebrates|In Situ Hybridization|Dach2 protein, mouse|Dach1 protein, mouse|LIM1 protein, Drosophila|Drosophila Proteins 36 DAZ3 19088127 Hum. Mol. Genet. 2008 10.1093/hmg/ddn427 31 0 3 1 Male|Humans|Y Chromosome, Human|Azoospermia|Oligospermia|Infertility, Male|*Chinese|Haplotypes|Spermatogenesis|Seminal Plasma Proteins|Chromosome Deletion|Genetic Loci|Gene Deletion 20 DAZ3 18990391 Fertil. Steril. 2008 10.1016/j.fertnstert.2008.08.135 11 0 1 1 Humans|Male|Deleted in Azoospermia 1 Protein|Chromosomes, Human, Y|Oligospermia|Azoospermia|Haplotypes|Infertility, Male|Gene Deletion|Genetic Loci|Genetic Variation|Seminal Plasma Proteins|Spermatogenesis|Phylogeny|RNA-Binding Proteins|Fertility 20 DGCR2 19022243 Exp. Mol. Pathol. 2008 10.1016/j.yexmp.2008.10.003 5 0 1 182 Humans|Female|Hypoparathyroidism|GATA3 protein, human|GATA3 Transcription Factor|Nephrosis|*Phenotype|Hearing Loss, Sensorineural|DiGeorge Syndrome|Mutations|Frameshift Mutation|Kidney|Gene Deletion 22 DKKL1 18818293 Endocrinology 2008 10.1210/en.2008-0673 14 1 3 98 Humans|Male|Animals|Mice|*Spermatocytes|*Testosterone|FASLG protein, human|Fas Ligand|Testis|*Apoptosis|Spermatogenesis|Leydig Cells|fas Receptor|Sperm Count|*Testosterone Congeners|DKKL1 protein, human|Intercellular Signaling Peptides and Proteins 22 DKKL1 18442417 BMC Genomics 2008 PMC2386486 10.1186/1471-2164-9-197 8 14 1 98 Female|Mice|Animals|*Transcriptome Analysis|Lactation|Mammary Glands, Animal|Milk|Fecundity|Weaning 22 DNAJC14 18684711 J. Biol. Chem. 2008 PMC5026489 10.1074/jbc.M803923200 38 7 3 65 *Molecular Chaperones|DNAJB1 protein, human|HSP40 Proteins|HSP70 Heat-Shock Proteins|Protein Folding|HSP110 Heat-Shock Proteins|ATPase|BCL2-associated athanogene 1 protein|DNA-Binding Proteins|Heat-Shock Proteins|Transcription Factors|HSC70 Heat-Shock Proteins|Protein Binding|Protein Denaturation|Luciferase|Adenosine Triphosphate 20 FASTK 19077453 Pancreatology 2008 10.1159/000178873 6 0 0 83 Carcinoma, Pancreatic Ductal|Cystadenoma, Serous|*Pancreas|Pancreatic Neoplasms 24 FASTK 18832135 Blood 2008 10.1182/blood-2008-04-153031 38 0 1 83 Humans|*Sezary Syndrome|Comparative Genomic Hybridization|*Mycosis Fungoides|Cutaneous T Cell Lymphoma|Skin Neoplasms|Skin|Oligonucleotide Array Sequence Analysis|Chromosome Aberrations|Polymerase Chain Reaction|Gene Expression 24 Fcrla 18802695 Cancer Immunol. Immunother. 2008 10.1007/s00262-008-0589-z 5 0 0 38 Humans|*Fc Receptor|Iran|*Acute Lymphoblastic Leukemia|Immunophenotyping|Flow Cytometry|Leukemias, Chronic B-Cell|*Acute Disease|PCR|B-Lymphocytes|FCRL1 protein, human|Membrane Proteins 27 Fcrla 18704934 Int. J. Cancer 2008 10.1002/ijc.23751 11 0 0 38 Humans|Aged|*Leukemia, Lymphocytic, Chronic, B-Cell|Iran|FCRL5 protein, human|*Fc Receptor|FCRL4 protein, human|FCRL2 protein, human|Receptors, Cell Surface|B Cells|FCRL1 protein, human|Membrane Proteins|Flow Cytometry|Gene Expression|RNA, Messenger 27 Fcrla 18314442 Blood 2008 PMC2435687 10.1182/blood-2008-01-131359 20 0 2 38 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|ZAP70 protein, human|ZAP-70 Protein-Tyrosine Kinase|ADP-ribosyl Cyclase 1|FCRL2 protein, human|*Receptors, Cell Surface|*Mutation|Immunoglobulin Variable Region|*Disease Progression|Prognosis|Immunoglobulin Heavy Chains|B-Lymphocytes|Membrane Glycoproteins|Oligonucleotide Array Sequence Analysis|FCRL1 protein, human|Membrane Proteins 27 Fcrla 18241881 J. Immunol. Methods 2008 10.1016/j.jim.2007.12.016 0 0 0 38 Pregnancy|Mice|Animals|Female|*Epitopes|alkaline phosphatase, placental|*Alkaline Phosphatase|Hybridoma|Antibodies, Monoclonal|Antibody Specificity|FCRL4 protein, human|Receptors, Fc|Enzyme-Linked Immunosorbent Assay|Antigen|Immunization|Immune Sera|Mice, Inbred BALB C|GPI-Linked Proteins 27 FERD3L 18544995 Oncology 2008 10.1159/000139124 23 2 4 19 *CpG Islands|*Phenotype|*Neuroblastomas|Promoter Regions, Genetic|DNA Methylation|Gene Silencing|Prognosis 21 FERD3L 18418688 Cerebellum 2008 10.1007/s12311-008-0014-3 3 0 0 19 Spinocerebellar ataxia 21|*Ataxia, Spinocerebellar|*Spinocerebellar Degenerations|Genetic Linkage|Pedigree|DNA Mutational Analysis|*Basal Ganglia Diseases|Chromosome Mapping|Mutations|*Cognitive Impairment, Mild 21 FJX1 18604206 Nat. Genet. 2008 10.1038/ng.179 229 5 14 72 Animals|Humans|*Signal Transduction|Cell Polarity|Drosophila Proteins|Drosophila|*Cell Division|Cadherins|Gene Expression Regulation, Developmental|*Polycystic Kidney Diseases|Membrane Proteins|Transcription Factors|*Orientation, Spatial|FAT4 protein, human|Tumor Suppressor Proteins|FJX1 protein, human|prickle protein, Drosophila 26 FKBP11 18974375 Blood 2008 PMC2628370 10.1182/blood-2008-02-140996 10 0 0 61 *Lymphoma, B-Cell, Marginal Zone|Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein|*Gene Expression Profiling|Translocation, Genetic|B-Cell CLL-Lymphoma 10 Protein|Lymphoma, Large B-Cell, Diffuse|Neoplasm Proteins|In Situ Hybridization, Fluorescence|*Microarray Analysis|Caspases|B-Lymphocytes|Trisomy|Lymphoid Tissue|Adaptor Proteins, Signal Transducing|Nuclear Factor-Kappab|Biological Products 21 FKBP11 18948221 Fungal Genet. Biol. 2008 10.1016/j.fgb.2008.09.011 3 0 1 61 *Neurospora crassa|*Tacrolimus|FKBP22|*FK506 Binding Proteins|FKBP-13|Folding, Protein|Fungal Proteins|Endoplasmic Reticulum|Amino Acid Sequence|Nuclear Protein|Mitochondria 21 FKBP11 18448419 Mol. Cell Proteomics 2008 PMC2500228 10.1074/mcp.M700478-MCP200 50 0 2 61 Mice|Animals|*Diabetes Mellitus, Type 2|*Proteomics|Endoplasmic Reticulum-Associated Degradation|Pancreatic beta Cells|Insulin|Insulin Resistance|Islets of Langerhans|Insulin Secretion|Proteome|Energy Metabolism|Mitochondria|Mice, Transgenic|Gene Expression|Blotting, Western|Muscle, Skeletal 21 GBX1 18198279 Physiol. Genomics 2008 10.1152/physiolgenomics.00256.2007 11 0 1 17 PAX7 protein, human|*PAX7 Transcription Factor|*Genome|Chromatin Immunoprecipitation|Gene Expression Regulation, Developmental|Neural Crest|Embryonic Development|Transfections 34 GMFB 18925664 Am. J. Med. Genet. A 2008 10.1002/ajmg.a.32519 12 0 0 125 Humans|Female|Animals|Mice|Infant|*Polysyndactyly|*Eye Abnormalities|Chromosome Deletion|Comparative Genomic Hybridization|Abnormalities, Multiple|*Psychomotor Disorders|In Situ Hybridization, Fluorescence|*Heterozygote|*Feet|Eye|BMP4 protein, human|Bone Morphogenetic Protein 4|*Corneal Opacity 26 GMFB 18275612 Proteome Sci 2008 PMC2265686 10.1186/1477-5956-6-8 35 7 0 125 Humans|*Parkinson Disease|*Proteome|*Substantia Nigra 26 GOLGA3 19028683 J. Biol. Chem. 2008 PMC2615508 10.1074/jbc.M807263200 13 2 0 189 Humans|*Active Transport, Cell Nucleus|Golgins|Golgi Apparatus|Caspases|Vesicular Transport Proteins|Membrane Proteins|Carrier Proteins|Cell Nucleus|Protein Binding|HeLa Cells|Autoantigens|Apoptosis|Binding Sites|Amino Acid Sequence|Sumoylation 46 GOLGA3 18564178 FEBS J. 2008 10.1111/j.1742-4658.2008.06517.x 8 2 1 189 Animals|serine racemase|*Amino Acids|*Racemases|Serine|Cations, Divalent|*Brain|Pyridoxal Phosphate|N Methyl D Aspartate Receptors|Sequence Homology, Amino Acid|Cell Line|Glycine|Calcium|Magnesium|Catalysis 46 GPR85 18442421 Immunome Res 2008 PMC2394514 10.1186/1745-7580-4-5 199 23 10 29 Animals|Mice|*G-Protein-Coupled Receptors|Macrophages|Lipopolysaccharides|Monocytes|RNA, Messenger 25 GPR85 18413613 Proc. Natl. Acad. Sci. U.S.A. 2008 PMC2299221 10.1073/pnas.0710717105 22 0 1 29 Humans|Animals|Mice|*Organ Size|*Schizophrenia|*Receptors, G-Protein-Coupled|Brain|Memory|SNPs|Hippocampus|Nerve Tissue Proteins|Genetic Predisposition to Disease|Alleles|Phenotype|Mice, Transgenic 25 GRIN3B 19056275 J Clin Neurosci 2008 10.1016/j.jocn.2007.11.015 1 0 0 31 Humans|*Comparative Genomic Hybridization|*Intracranial Aneurysm|*DNA Copy Number Variations|*Ruptured Aneurysms|Oligonucleotide Array Sequence Analysis|*DNA, Complementary|Chromosome Aberrations|Gene Expression Profiling|Chromosome Mapping|Chromosomes, Human|Genetic Predisposition to Disease 21 HMGN3 18502697 Gene Expr. Patterns 2008 PMC2525792 10.1016/j.gep.2008.04.002 10 0 0 72 Mice|Animals|HMGN3 protein, human|*HMGN|HMGN1 Protein|HMGN2 Protein|Chromatin|Nucleosomes|Retina|Lens, Crystalline|Nuclear Proteins|mRNA|HMGN3 protein, mouse 28 hus1b 18950845 Gynecol. Oncol. 2008 10.1016/j.ygyno.2008.09.012 5 0 1 18 *Polymorphism, Single Nucleotide|*Case-Control Studies|*Penetrance|*Risk Factors|Genetic Susceptibility|Genotype 32 hus1b 18842633 Nucleic Acids Res. 2008 PMC2582629 10.1093/nar/gkn686 26 26 1 18 Humans|Mice|Animals|*DNA Mismatch Repair|MLH1 protein, human|*MutL Protein Homolog 1|Nuclear Proteins|Adaptor Proteins, Signal Transducing|DNA-Binding Proteins|DNA Repair|Mutation|Saccharomyces cerevisiae|Recombination, Genetic 32 hus1b 18794804 Oncogene 2008 PMC2605171 10.1038/onc.2008.336 5 37 0 18 *Etoposide|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Apoptosis Regulatory Proteins|Bcl-2-Like Protein 11|Apoptosis|Proto-Oncogene Proteins|Membrane Proteins|Tumor Suppressor Proteins|DNA Damage|*Cell Death|Mitochondria 32 hus1b 18291413 J. Mol. Biol. 2008 PMC2680686 10.1016/j.jmb.2007.10.074 21 6 2 18 Humans|Animals|*Flap Endonucleases|*DNA Replication|Exodeoxyribonucleases|RecQ Helicases|Werner Syndrome Helicase|Base Excision Repair|DNA|Endonucleases|Proliferating Cell Nuclear Antigen|Protein Binding|Binding Sites|Kinetics 32 IMPG1 18466325 J. Neurochem. 2008 10.1111/j.1471-4159.2008.05468.x 0 2 0 26 Animals|*Hyaluronic Acid|*Chickens|*Sialoglycoproteins|*Photoreceptor Cells, Vertebrate|Proteoglycans|Extracellular Matrix Proteins|Hyaluronan Receptors|Retina|Amino Acid Sequence|Eye Proteins|Binding Site|Protein Binding|Western Blotting|Mutagenesis, Site-Directed|Biotinylations 29 INSL4 18616428 Annu. Rev. Cell Dev. Biol. 2008 10.1146/annurev.cellbio.24.110707.175418 76 0 5 17 Animals|Female|Pregnancy|*Placenta|syncytin|Pregnancy Proteins|Gene Products, env|Placental Development|Endogenous Retroviruses|Trophoblasts|Retroelements|Transcription Factors|Evolution, Molecular|Promoter Regions, Genetic|Phylogeny|Gene Expression Regulation, Developmental|Isoforms 45 ITM2C 19114711 J. Biol. Chem. 2008 10.1074/jbc.M807485200 20 0 0 80 *Proteolysis|signal peptide peptidase|Aspartic Acid Endopeptidases|gamma-Secretase|ADAM10 Protein|ADAM Proteins|Membrane Protein|Cell Membrane|Presenilin|Substrate Specificity|Signal Transduction 27 ITM2C 18524483 Neurosci. Lett. 2008 10.1016/j.neulet.2008.04.009 12 2 1 80 Mice|Animals|oren gedoku to|Neurodegenerative Diseases|*Hippocampus|*Cerebral Cortex|*Drugs, Chinese Herbal|*Gene Expression|Memory|Alzheimer Disease|cDNA Microarray|Aging|Disease Models, Animal|Learning|AMFR protein, human|Receptors, Autocrine Motility Factor|Cstf2t protein, mouse|Cleavage Stimulation Factor|Ddx3x protein, mouse|RNA Helicases 27 KLF16 18472212 Mol. Cell. Endocrinol. 2008 10.1016/j.mce.2008.03.011 2 2 0 93 Animals|Mice|*Gene Expression Regulation|Promoter Regions, Genetic|Transcription Initiation Site|Transcription, Genetic|Base Sequence|Binding Sites|*Regulatory Gene|Sp1 Transcription Factor|Activation, Transcriptional|Transfection|Electrophoretic Mobility Shift Assay|DRD2 protein, human|Receptors, Dopamine D2 26 KLK9 19090718 Biol. Chem. 2008 PMC2838389 10.1515/BC.2009.026 15 1 1 20 Humans|KLK15 protein, human|*Kallikrein|Hydrolysis|Recombinant Proteins 36 METRN 18974090 Toxicol. Sci. 2008 PMC2768398 10.1093/toxsci/kfn221 13 0 1 47 Mice|Animals|*Neurulation|*Cadmium|*Toxicogenetics|*Mice, Inbred C57BL|Teratogens|Neural Tube Defects|Strain, Inbred Mouse|Organogenesis|Gene Expression Regulation, Developmental|Gene Expression Profiling|Cell Cycle|*Biochemical Phenomena|Species Specificity 22 myo1f 19027848 Biochim. Biophys. Acta 2008 10.1016/j.bbadis.2008.10.017 18 1 1 128 Humans|*Hearing Loss|*Deafness|Hearing Loss, Sensorineural|Myosins|Myosin Type I|Mutations, Missense|Protein Conformation|Mutations|Amino Acid Sequence|Pedigree|Protein Binding|Models, Molecular|Binding Site|Models, Chemical|Europe|MYO1C protein, human|MYO1F protein, human 25 MYO5C 18434623 Am. J. Physiol., Cell Physiol. 2008 PMC2493552 10.1152/ajpcell.00330.2007 18 1 0 604 Animals|Rabbits|*Secretory Vesicles|*Lacrimal Apparatus|*Acinar Cells|MYO5A protein, human|*Myosin V|*Exocytosis|*Myosin|*Myosin Heavy Chains|Actin|rab3 GTP-Binding Proteins|Sycn protein, rat|Carrier Proteins|Membrane Proteins|Carbachol|Protein Transport|Transduction, Genetic|Cells, Cultured|Tear 22 MYO5C 18201966 J. Biol. Chem. 2008 10.1074/jbc.M709150200 27 2 0 604 Animals|Humans|Kinetics|MYO5A protein, human|Myosin V|Myosin Heavy Chains|ATPase, Actomyosin|Actomyosin|Actin|Adenosine Diphosphate|Heavy Meromyosin|Protein Binding|Filaments, Actin|ATPase|Adenosine Triphosphate|Isoforms|Hydrolysis|Phosphates 22 NDFIP2 18776082 Blood 2008 10.1182/blood-2008-04-150953 50 5 3 108 Mice|Animals|*Ubiquitin|solute carrier family 11- (proton-coupled divalent metal ion transporters), member 2|*Cation Transport Proteins|Ubiquitination|Endosomal Sorting Complexes Required for Transport|Nedd4 Ubiquitin Protein Ligases|Membrane Proteins|*Homeostasis|Ubiquitin-Protein Ligases|Iron|Ion Transport|NDFIP2 protein, mouse 24 NHLH1 18231642 Neoplasia 2008 PMC2213903 10.1593/neo.07891 25 1 2 132 Humans|Mice|Animals|Child|*Hedgehog Proteins|*Medulloblastoma|Patched Receptors|Zinc Finger Protein GLI1|Cerebellar Neoplasms|Signal Transduction|Cerebellum|Transcription Factor|Trans-Activators|Gene Expression Regulation, Developmental|Cell Proliferation|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Neoplastic|INSM1 protein, human|Repressor Proteins|Insm1 protein, mouse|DNA-Binding Proteins 43 OLFML3 18602390 Exp. Eye Res. 2008 PMC2572563 10.1016/j.exer.2008.06.006 15 0 1 48 Humans|Mice|Animals|trabecular meshwork-induced glucocorticoid response protein|*Aqueous Humor|*Mice, Transgenic|*Eye Proteins|*Cytoskeletal Proteins|olfactomedin|*Glycoprotein|Trabecular Meshwork|Glaucoma, Primary Open Angle|*Gene Expression|Extracellular Matrix Proteins|Gene Expression Regulation|Western Blotting|RNA, Messenger|Mutation|Real Time PCR|LPHN3 protein, mouse|Receptors, Peptide 21 OTOP1 18661184 J. Assoc. Res. Otolaryngol. 2008 PMC2580812 10.1007/s10162-008-0132-0 6 0 0 24 Animals|Mice|Humans|*Otolithic Membrane|*Patient Discharge|Saccule and Utricle|Vestibule, Labyrinth|Hair Cells, Vestibular|Neurons, Afferent|Gravity|*Axons 23 OTOP1 18254951 BMC Evol. Biol. 2008 PMC2268672 10.1186/1471-2148-8-41 13 1 0 24 Animals|*Invertebrate|Evolution, Molecular|Amino Acid Sequence|Multigene Family|Phylogeny|Zebrafish|Membrane Proteins|Otoliths 23 PLAC4 19097032 Prenat. Diagn. 2008 10.1002/pd.2163 2 0 0 0 Pregnancy|Humans|Female|*Down Syndrome|*mRNA|*Chorionic Gonadotropin, beta Subunit, Human|*Trisomy|Pregnancy-Associated Plasma Protein-A|Prenatal Diagnosis|Biomarkers|Case-Control Studies 22 PLAC4 18207470 Semin Fetal Neonatal Med 2008 10.1016/j.siny.2007.11.001 5 0 0 0 Pregnancy|Humans|Female|*Prenatal Diagnosis|Aneuploidies|Down Syndrome|Fetus|RNA|Maternal-Fetal Exchange|DNA|Genetic Testing|mRNA|Cystic Fibrosis|Prenatal Care|Epigenesis, Genetic|Chromosome 18 22 POU6F1 18323601 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2008 PMC2374152 10.1107/S1744309108003370 1 0 0 30 Humans|*X-Rays|*Crystallization|*DNA|POU Domain Factors|Homeodomain Proteins|CEBPB protein, human|*CCAAT-Enhancer-Binding Protein-beta|Nerve Tissue Proteins|Cell Differentiation 34 PPP1R3A 18232732 PLoS Med. 2008 PMC2214798 10.1371/journal.pmed.0050027 16 23 0 909 Humans|Mice|Animals|*Glycogen|Glycogen Synthase|Muscle, Skeletal|Glycogen Phosphorylase|*Glycogenolysis|Insulin|Glucose|Protein Phosphatase 1|PPP1R3A protein, human|Phosphoprotein Phosphatases 40 PTPRCAP 18205604 Biochemistry Mosc. 2008 10.1134/s0006297907110077 4 0 1 34 *CD4 Antigens|lck Kinase|PTPRC protein, human|Leukocyte Common Antigens|CD71 antigen|Antigens, CD|*Cell Membrane|Transferrin Receptor|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Lymphocyte Activation|Protein Tyrosine Phosphatases|Phosphorylation|Protein Binding|Phosphatase, Phosphoprotein 48 PYHIN1 18247378 Mol. Carcinog. 2008 PMC2596649 10.1002/mc.20423 4 24 0 57 SERPIN-B5|*Transcriptional Activation|*Serpins|*Upregulation|HDAC1 protein, human|Histone Deacetylase 1|Genes, Tumor Suppressor|Promoter Regions, Genetic|DNA Methylation|Cell Line, Tumor|*Cell Movement|Histone Deacetylase Inhibitors|TYRP1 protein, human|*Membrane Glycoproteins|mRNA|Downregulation|Interferons 20 RAPGEF6 18718982 J. Med. Genet. 2008 10.1136/jmg.2008.060657 6 0 0 96 Humans|*Haplotypes|*Asian Continental Ancestry Group|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Linkage Disequilibrium|ACSL6 protein, human|*Coenzyme A Ligases|Gene Frequency|Genetic Linkage|Case-Control Studies 25 RAPGEF6 18585005 Cell. Signal. 2008 10.1016/j.cellsig.2008.05.006 17 5 0 96 RAP1A protein, human|rap1 GTP-Binding Proteins|*Intercellular Junctions|CDH1 protein, human|E Cadherin|Adherens Junction|Guanine Nucleotide Exchange Factor|Cell Adhesion|Antigens, CD|Nerve Tissue Proteins|Monomeric GTP-Binding Proteins 25 RNF39 19050382 AIDS 2008 10.1097/QAD.0b013e32831db247 44 0 1 8 *HLA-C Antigens|*HIV-1|Genome-Wide Association Study|*HIV Infections|Viral Load|*Genes, MHC Class I|CD4 Lymphocyte Count|Single Nucleotide Polymorphisms|HIV Seropositivity|Major Histocompatibility Complex|Disease Progression 22 RTTN 18329748 Virus Res. 2008 10.1016/j.virusres.2008.01.012 13 0 0 72 Mice|Animals|*HIV-1|HIV Vaccines|HIV Antibodies|Gene Products, gag|polypeptide C|*Polypeptides|Gene Products, env|Virion|Vaccines, DNA|Baculovirus|T-Lymphocytes, Cytotoxic|Mice, Inbred BALB C|*Reading Frames|*Chimera|Cell Line 21 SAMSN1 18778695 Brain Res. 2008 PMC2783475 10.1016/j.brainres.2008.08.023 80 0 9 51 *Schizophrenia|Cortex, Prefrontal|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Profiles|RNA, Messenger|Real-Time Polymerase Chain Reaction 25 SAMSN1 18523997 Genes Chromosomes Cancer 2008 10.1002/gcc.20582 34 0 1 51 Humans|*Homozygote|Sequence Deletion|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Carcinoma, Small Cell|Genes, Tumor Suppressor|Loss of Heterozygosity|Chromosome Mapping|Gene Deletion|Genome|USP25 protein, human|Ubiquitin Thiolesterase|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport 25 SCGB1D2 18630503 Anticancer Res. 2008 0 0 0 18 Humans|Female|*Mammaglobin B|SCGB1D2 protein, human|*Secretoglobins|SCGB2A2 protein, human|Mammaglobin A|Uteroglobin|Neoplasm Proteins|Biomarkers, Tumor|Proteolipids|Gene Expression Regulation, Neoplastic|Carrier Proteins|Ovarian Neoplasms|Cell Line, Tumor|Myelin Proteins|Up-Regulation|Cell Proliferation 156 SLC22A9 18609448 Xenobiotica 2008 10.1080/00498250802187286 0 1 0 139 Humans|ABCG2 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 2|*Propionates|*alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid|HEK293 Cells|Neoplasm Proteins|multidrug resistance-associated protein 2|Multidrug Resistance-Associated Proteins|*Kidney Tubules|*Biological Transport|Organic Anion Transporters, Sodium-Independent|p-Aminohippuric Acid|ATP-Binding Cassette Transporters|Organic Anion Transporters|Kidney|Membrane Transport Proteins 30 SLC22A9 18501590 J. Steroid Biochem. Mol. Biol. 2008 10.1016/j.jsbmb.2008.04.001 12 0 1 139 Humans|Female|Pregnancy|HEK293 Cells|Kinetics|*Organic Anion Transporters|*Biological Transport|Organic Anion Transporters, Sodium-Independent|Trophoblasts|estrone sulfate|Estrone|Placenta|Dehydroepiandrosterone Sulfate|Fetus|Sulfates 30 SLC22A9 18441515 Cell. Physiol. Biochem. 2008 10.1159/000129385 10 1 0 139 Animals|Rats|*Organic Anion Transporters|*Kidney|Organic Anion Transporters, Sodium-Independent|*Kidney Tubules|Biological Transport|Kidney Tubules, Proximal|estrone sulfate|Estrone|Probenecid|Xenopus laevis|ochratoxin A|Ochratoxins|Carrier Proteins|Taurocholate|Oocytes|Cloning, Molecular|Dehydroepiandrosterone Sulfate 30 SLC22A9 18414781 J. Hum. Genet. 2008 10.1007/s10038-008-0288-9 10 0 0 139 Humans|Organic Anion Transport Protein 1|Organic Anion Transporters, Sodium-Independent|*Kidney|Organic Cation Transporter 2|Organic Cation Transport Proteins|Organic Anion Transporters|*Ion Transport|*Polymorphism, Genetic|RNA, Messenger 30 STOML1 19034969 World J. Gastroenterol. 2008 PMC2773308 10.3748/wjg.14.6662 12 0 1 71 *Colorectal Cancers|*Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Genes, APC|Gene Expression Regulation, Neoplastic|Wnt Proteins|Adenocarcinoma|Cell Transformation, Neoplastic|Signal Transduction|Cell Line, Tumor 20 STOML1 18267007 BMC Evol. Biol. 2008 PMC2258279 10.1186/1471-2148-8-44 16 1 1 71 Humans|Evolution, Molecular|Phylogeny|Multigene Family|Gene Duplication|Amino Acid Sequence|Conserved Sequence|Sequence Alignment|Membrane Protein 20 STOML1 18266782 Traffic 2008 PMC2329822 10.1111/j.1600-0854.2008.00714.x 29 11 3 71 Humans|Mice|Animals|*Immunological Synapses|*T-Lymphocytes, Cytotoxic|Rab27a Protein|*Plasma Membrane|Exocytosis|rab GTP-Binding Proteins|Secretory Vesicles|Membrane Proteins|Isoforms|Lysosomes|Protein Binding|Biological Transport|JFC1 protein, human 20 STOML1 18237819 Eur. J. Cell Biol. 2008 10.1016/j.ejcb.2007.12.001 40 2 3 71 Humans|Rats|Animals|flotillins|*Membrane Proteins|*Protein Transport|Membrane Microdomains|Plasma Membrane|Endocytosis|Golgi Complex|Epidermal Growth Factor|Signal Transduction|*Cell Movement|PC12 Cells|Cytoplasm|HeLa Cells|Prions 20 SVOP 19013223 Gene 2008 10.1016/j.gene.2008.10.008 3 0 0 115 Animals|Mice|Humans|*Synaptic Vesicles|HEK293 Cells|Svop protein, mouse|*Nerve Tissue Proteins|*Vesicular Transport Proteins|Central Nervous System|Brain|Promoter Regions, Genetic|Neurons|In Situ Hybridization|Gene Expression Profiling|cDNA|Transfections|Gene Expression Regulation, Developmental|RNA, Messenger 26 TARBP1 18303858 Biochemistry 2008 10.1021/bi702429m 6 0 1 41 Humans|*RNA Recognition Motif|U1A protein|Ribonucleoprotein, U1 Small Nuclear|*RNA Binding Protein|RNA Conformations|RNA|RNA Sequence|Protein Conformation|Protein Binding|Amino Acid Sequence|negative elongation factor|*Transcription Factors|Models, Molecular 26 TCF15 18361414 Mol. Reprod. Dev. 2008 PMC5703192 10.1002/mrd.20902 10 43 0 58 Mice|Male|Animals|*Testis|Helix-Loop-Helix Domain|Basic Helix-Loop-Helix Transcription Factors|Sertoli Cells|*Signal Transduction|Cell Differentiation|cAMP Response Element Binding Protein|*Sex Differentiation|Promoter Regions, Genetic|*Dimerization|Recombinant Proteins|Follicle Stimulating Hormone|Transfection 39 TEX19 18802469 PLoS Genet. 2008 PMC2531233 10.1371/journal.pgen.1000199 35 15 5 48 Male|Humans|Mice|Animals|*Endogenous Retroviruses|*Spermatogenesis|Synapsis|Meiosis|Testis|Spermatocytes|Nuclear Proteins|DNA Breaks, Double-Stranded|RNA-Binding Proteins|Mice, Knockout|Endodeoxyribonucleases|Transcription Factors|Infertility, Male|Chromosomes|Tex19 protein, human|Tex19 protein, mouse 20 TLE6 18804437 Dev. Cell 2008 PMC2597058 10.1016/j.devcel.2008.07.010 79 5 5 17 Humans|Female|Mice|Animals|*Embryonic Development|Blastocyst|Oogenesis|Embryo, Mammalian|Oocytes|Zygotes|Proteins|Gene Expression Regulation, Developmental|Fertilization|Amino Acid Sequence|Ovulation|Divisions, Cell|Tle6 protein, human|Transcription Factors|filia protein, mouse 23 TLE6 18778483 BMC Dev. Biol. 2008 PMC2551604 10.1186/1471-213X-8-81 16 35 0 17 Animals|Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|Homeodomain Proteins|Pancreas|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Islets of Langerhans|Cell Differentiation|*Organogenesis|Insulin 23 TLE6 18551179 PLoS Genet. 2008 PMC2410297 10.1371/journal.pgen.1000092 15 32 0 17 Humans|Mice|Animals|*DNA Mismatch Repair|Escherichia coli|MLH3 protein, human|*MutL Proteins|PMS2 protein, human|Mismatch Repair Endonuclease PMS2|MLH1 protein, human|MutL Protein Homolog 1|DNA Repair Enzymes|DNA-Binding Proteins|Nuclear Proteins|Adenosine Triphosphatases|*Cell Transformation, Neoplastic|*Tumorigenesis|Carrier Proteins|Adaptor Proteins, Signal Transducing|DNA Repair|Base Pair Mismatch 23 TMEM135 18637193 BMC Genomics 2008 PMC2492879 10.1186/1471-2164-9-340 34 5 2 40 Humans|*Adipogenesis|*Transcriptome|Osteoblast|Mesenchymal Stem Cells|Adipocyte|Cell Differentiation|Bone Marrow Cells|Osteogenesis|*Multipotent Stem Cells|*Computational Biology|Gene Expression Profiling|Signal Transduction|Cells, Cultured 20 TTC12 18828801 Alcohol. Clin. Exp. Res. 2008 PMC2975565 10.1111/j.1530-0277.2008.00800.x 41 7 3 11 Humans|*Haplotypes|Alcohol Dependence|*Neural Cell Adhesion Molecules|Linkage Disequilibrium|*Ethanol|Receptors, Dopamine D2|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|*Drug Dependence|European Continental Ancestry Group|CD56 Antigen|Protein-Serine-Threonine Kinases|*Comorbidity|TTC12 protein, human|Proteins|ANKK1 protein, human 24 TTC12 18621654 Science 2008 10.1126/science.1155372 9 0 0 11 Humans|Receptors, Dopamine D2|Genotype|Dopamine|Protein-Serine-Threonine Kinases|Polymorphism, Single Nucleotide 24 ZC3H12D 18682727 PLoS ONE 2008 PMC2478707 10.1371/journal.pone.0002880 65 10 2 498 Humans|Mice|Animals|*Macrophage Activation|Phylogeny|*Zinc Finger|Gene Expression Regulation, Plant|Genes, Plant|Plant Proteins|Multigene Family|Chromosomes, Plant|Chromosome Mapping|Gene Duplication|Amino Acid Sequence|Stress, Physiological|*Survey|ZC3H12A protein, human|Ribonucleases|Transcription Factors|MBNL3 protein, mouse|Carrier Proteins 20 ZC3H12D 18178554 J. Biol. Chem. 2008 10.1074/jbc.M707861200 81 4 5 498 *Macrophages|NOS2 protein, human|Inducible Nitric Oxide Synthase|Macrophage Activation|Lipopolysaccharides|Nuclear Factor-Kappab|Tumor Necrosis Factor-alpha|Cytokines|PHF20 protein, human|Signal Transduction|Nitric Oxide|Promoter Regions, Genetic|*Biomarkers, Tumor|Short Interfering RNA|Zinc Fingers 20 ACTBP2 17821954 Clin. Lab. 2007 0 0 0 0 Humans|*Short Tandem Repeat|*Genetics, Population|Gene Frequency|DNA Fingerprinting|PCR|Alleles|Amelogenin|Heterozygote|European Continental Ancestry Group 67 AGAP1 18003747 Am. J. Physiol., Cell Physiol. 2007 10.1152/ajpcell.00292.2007 10 1 0 202 Humans|Animals|*GTPase-Activating Proteins|*Substrate Specificity|ADP-ribosylation factor 6|*ADP-Ribosylation Factor|ADP-Ribosylation Factor 1|Carrier Proteins|Amino Acid Sequence|Guanine Nucleotide Exchange Factors|Cytoplasm|Signal Transduction|Sequence Homology, Amino Acid|ACAP1 protein, human 25 ANKRD17 17276651 Microb. Pathog. 2007 10.1016/j.micpath.2006.12.002 5 15 0 122 Chlorocebus aethiops|Animals|Humans|*Enterovirus|*Enterovirus A, Human|*Ornithine Decarboxylase|Vero Cells|*Ankyrin Repeat|Hand, Foot and Mouth Disease|Enterovirus Infections|Capsid Proteins|Capsid|Antibodies, Viral|East Asia 24 AP3M2 17293072 Brain Dev. 2007 10.1016/j.braindev.2006.12.004 0 0 0 40 Humans|Animals|Mice|Japan|*Mutation|*Epilepsy|DNA Mutational Analysis|Genetic Predisposition|Exons|Febrile Seizure|Pedigree|Introns|Nonsense Mutations 25 CLIC6 17575528 J. Clin. Gastroenterol. 2007 PMC2860960 10.1097/MCG.0b013e31803233b7 30 2 0 37 *H(+)-K(+)-Exchanging ATPase|Parietal Cells, Gastric|Gastric Acid|Proton Pump Inhibitors|Anti-Ulcer Agents|Stomach|Gastric Mucosa|*Ion Transport|Enzyme Inhibitors|ATPase|Proton Pump|Binding Site|*Biochemical Phenomena|ezrin|Cytoskeletal Proteins 21 CST8 17486270 Asian J. Androl. 2007 10.1111/j.1745-7262.2007.00260.x 2 0 0 190 Mice|Male|Animals|*Epididymis|*Testis|*Spermatogenesis|Cystatins 31 CYP4X1 18088177 Radiat. Res. 2007 10.1667/RR0487.1 22 0 3 8 Humans|*Gamma Rays|*Transcriptome|*Lymphocytes|Gene Expression Regulation|DNA Microarrays|DNA Repair|Dose-Response Relationship, Radiation|DNA Damage|Chromosome|Gene Expression Profiling|Cells, Cultured|Cell Cycle|DNA|Cell Proliferation|Up-Regulation|XAB2 protein, human|Transcription Factors|STK25 protein, human 26 DACH2 17873280 J. Biol. Chem. 2007 10.1074/jbc.M706268200 60 2 4 37 HDAC4 protein, human|*Histone Deacetylase|*Repressor Proteins|Myogenin|Gene Expression Regulation|Transcription Factor|Myogenic Regulatory Factors|Cell Nucleus|DNA-Binding Proteins|Signal Transduction|Activation, Transcription|Neuromuscular Junction|Gene Expression|Muscle, Skeletal 36 DAZ3 17416365 Fertil. Steril. 2007 10.1016/j.fertnstert.2007.01.038 9 1 3 1 Humans|Male|Deleted in Azoospermia 1 Protein|Oligospermia|Azoospermia|Chromosomes, Human, Y|Infertility, Male|Chromosome Deletion|Spermatogenesis|Genetic Loci|Seminal Plasma Proteins|Gene Deletion|Case-Control Studies|Chile 20 DAZ3 17211466 Br. J. Cancer 2007 PMC2360005 10.1038/sj.bjc.6603557 8 0 0 1 Humans|Male|Adolescent|Young Adult|Adult|Middle Aged|Testicular Germ Cell Tumor|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Chromosomes, Human, Y|Infertility, Male|Chromosome Deletion 20 DGCR2 17982252 Cell. Physiol. Biochem. 2007 10.1159/000110430 63 0 3 182 *Schizophrenia|Genetic Predisposition to Disease|GABRA6 protein, human|Receptors, GABA-A|Polymorphism, Single Nucleotide|reelin protein|Nerve Tissue Proteins|Dopamine|Receptor, ErbB-4|Carrier Proteins|Serine Endopeptidases|Cell Adhesion Molecules, Neuronal|Extracellular Matrix Proteins 22 DGCR6 17982252 Cell. Physiol. Biochem. 2007 10.1159/000110430 63 0 3 67 *Schizophrenia|Genetic Predisposition to Disease|GABRA6 protein, human|Receptors, GABA-A|Polymorphism, Single Nucleotide|reelin protein|Nerve Tissue Proteins|Dopamine|Receptor, ErbB-4|Carrier Proteins|Serine Endopeptidases|Cell Adhesion Molecules, Neuronal|Extracellular Matrix Proteins 24 DMRTA2 17938377 Hypertension 2007 10.1161/HYPERTENSIONAHA.107.093138 7 1 0 12 Rats|Animals|*Quantitative Trait Loci|*Blood Pressure|*Rats, Inbred Lew|*Blood Pressure Determination|Animals, Congenic|Chromosome Mapping|Rats, Inbred Dahl|Hypertension|Oligonucleotide Array Sequence Analysis|Alleles 25 DNAJC14 17363375 J. Biol. Chem. 2007 10.1074/jbc.M608846200 31 3 1 65 GTP-Binding Protein gamma Subunits|GTP-Binding Protein beta Subunits|*Molecular Chaperone|Heterotrimeric G-Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Signal Transduction|Isoforms|Dimerization|Amino Acid Sequence|Carrier Proteins|Receptors, Dopamine 20 EPB41L4B 17280610 Mol. Cancer 2007 PMC1797054 10.1186/1476-4598-6-14 17 15 2 90 Humans|Male|*DNA Methylation|*Chromosomes, Human, Pair 8|*Prostate Cancer|Long Interspersed Nucleotide Elements|*Cytoskeleton|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Gene Expression Profiling|*Complement Factor B|Tumor Cells, Cultured|*Innate Immune Response 23 EPB41L4B 17219717 Folia Histochem. Cytobiol. 2007 32 0 0 90 *Erythrocyte Membrane|*Cytoskeletal Proteins|Focal Adhesions|PTK2 protein, human|Focal Adhesion Kinase 1|Membrane Proteins|Protein Binding|Spectrin|Focal Adhesion Kinase|Glycophorin C|Cell Motility|Cell Adhesion|Signal Transduction|Red Blood Cells|Actin|Amino Acid Sequence|Calmodulin|Actin Cytoskeleton 23 ETV3 18025162 J. Immunol. 2007 10.4049/jimmunol.179.11.7215 64 13 2 1655 Humans|Mice|Animals|*Signal Transduction|IL10 protein, human|IL10|STAT3 protein, human|STAT3 Transcription Factor|DNA-Binding Proteins|Macrophages|Trans-Activators|Suppressor of Cytokine Signaling Proteins|Suppressor of Cytokine Signaling 3 Protein|Repressor Proteins|Lipopolysaccharides|Interleukin-6|NF-kappa B|Protein Biosynthesis|*Anti-Inflammatory Agents|Co-Repressor Proteins|ETV3 protein, human 23 ETV3 17525531 Cell Cycle 2007 10.4161/cc.6.13.4336 7 7 0 1655 Transcription Factors|DNA-Binding Proteins|Repressor Proteins|Proto-Oncogene Proteins c-ets|Transcription, Genetic|Trans-Activators|Proto-Oncogene Proteins|Signal Transduction|Cell Differentiation|Promoter Regions, Genetic|Proto-Oncogene Protein c-ets-2|Oncogenes|Cell Cycle Genes|Transfection 23 EVX2 17245451 PLoS ONE 2007 PMC1766471 10.1371/journal.pone.0000175 5 2 1 14 *Intergenic Region|*Transcription Factors|*Promoter Regions, Genetic|Hox Genes|Homeodomain Proteins|Enhancer Elements, Genetic|Gene Expression Regulation, Developmental|Limb|Transgenes 33 FASTK 18007665 Cell Death Differ. 2007 10.1038/sj.cdd.4402258 34 0 0 83 Humans|Rats|Animals|*RNA Interference|Neurite|*Neurite Outgrowth|Growth Cones|Neurons|RNA, Small Interfering|ROCK1 protein, human|rho-Associated Kinases|Carrier Proteins|Transfection|Tyrosine Kinase|MAP4K4 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|MAST2 protein, human|Microtubule-Associated Proteins 24 FASTK 17592127 Proc. Natl. Acad. Sci. U.S.A. 2007 PMC2040905 10.1073/pnas.0704964104 16 0 0 83 Humans|*Alternative Splicing|*Threonine|*Serine|Exons|Introns|FGFR2 protein, human|Fibroblast Growth Factor Receptor 2|Splice Site, 5'|HeLa Cells|*Phosphoproteins|Cell Nucleus|mRNA|DNA Mutational Analysis 24 FKBP11 17623099 BMC Genomics 2007 PMC1959522 10.1186/1471-2164-8-230 32 72 3 61 Humans|*Interleukin-2|*Transcriptome|*Killer Cells, Natural|*Signal Transduction|Cytotoxicity, Immunologic|Lymphocyte Activation|Transcription, Genetic|Cytokines 21 FOXN2 17681238 Insect Biochem. Mol. Biol. 2007 PMC2441594 10.1016/j.ibmb.2007.05.008 23 3 0 138 28 GAGE1 17715884 Cancer Immun. 2007 PMC2935757 22 0 0 20 Male|Humans|Adult|Female|Pregnancy|*Testis|Antigens, Neoplasm|Neoplasm Proteins|Membrane Proteins|*Placenta|Ovary|Gene Expression Regulation, Neoplastic|Germ Cells|Antibodies, Monoclonal|Fetus|mRNA|Neoplasms 48 GAGE1 17709385 Mol. Cell. Biol. 2007 PMC2169050 10.1128/MCB.01120-07 29 3 1 20 Male|Humans|*Acetylation|*DNA Demethylation|HEK293 Cells|trichostatin A|Hydroxamic Acids|DNA Methylation|Promoter Regions, Genetic|Histones|RNA Polymerase II|Transcription Factors|Chromatin|Histone Deacetylase Inhibitors|Transcription, Genetic|Gene Silencing|Histone Deacetylases|Transcriptional Activation|DNA-Binding Proteins 48 GAGE1 17208940 Hum. Reprod. 2007 10.1093/humrep/del494 21 0 0 20 Male|Adult|Humans|*Testis|Antigens, Neoplasm|Neoplasm Proteins|Immunohistochemistry|Membrane Proteins|*Gonads|Germ Cells 48 GBX1 17990271 J. Comp. Neurol. 2007 PMC4916653 10.1002/cne.21524 49 0 4 17 Mice|Animals|*Amygdala|Transcription Factors|Homeodomain Proteins|Telencephalon|Gene Expression Regulation, Developmental|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Nerve Tissue Proteins|Basal Ganglia|*Gene Expression|Neurons|Lhx9 protein, mouse|LIM-Homeodomain Proteins 34 glycolisis 17400443 Surg Oncol 2007 10.1016/j.suronc.2007.02.001 5 0 0 0 *Cancer|*Inflammation|Oxidative Stress|Neovascularization, Pathologic|Leukocytes|Endocrine System|Biological Evolution|Ischemia|Capillaries 23 glycolisis 17345080 Appl. Microbiol. Biotechnol. 2007 10.1007/s00253-007-0910-3 2 0 0 0 *Ketones|NADP|Oxidation-Reduction|Alcohol Dehydrogenase|Synechococcus|Stereoisomerism|Ethanol|Regeneration 23 GOLGA3 18160786 Cytogenet. Genome Res. 2007 10.1159/000109623 4 0 0 189 Mice|Animals|*Transgenic Mouse|*Chromosome Aberrations|*Base Sequence|Translocation, Genetic|Chromosome Breakage|Gene Rearrangement|Chromosomes 46 GOLGA3 17888676 Mol. Cell. Neurosci. 2007 10.1016/j.mcn.2007.07.014 3 6 0 189 Humans|Rats|Male|Animals|*Phosphorylation|*Golgi Matrix Proteins|*Proto-Oncogene Proteins c-akt|HeLa Cells|*Protein A|*Apoptosis|GOLPH3 protein, human|Membrane Proteins|Golgi Apparatus|Caspases|Amino Acid Sequence|Cell Nucleus|Autoantigens|*Protective Agents|Transfection|Protein Binding|cDNA|*Brain Ischemia 46 GPR26 18037267 Mol. Cell. Probes 2007 10.1016/j.mcp.2007.10.002 2 0 0 71 Humans|*Glioblastoma|Brain Neoplasms|Glioma|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Brain|PCR|Cell Line, Tumor|Genetic Marker 20 GPR26 17363172 Biochim. Biophys. Acta 2007 10.1016/j.bbagen.2007.01.013 12 0 0 71 Animals|Mice|Humans|HEK293 Cells|*Tissue Distribution|GPRC5C protein, human|*Receptors, G-Protein-Coupled|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Amino Acid Sequence|GTP-Binding Protein alpha Subunits, Gq-G11|GTP-Binding Protein alpha Subunits|Mutagenesis, Site-Directed|Sequence Homology, Amino Acid|Transfection 20 GRIN3B 17880385 Eur. J. Neurosci. 2007 10.1111/j.1460-9568.2007.05774.x 16 1 0 31 Humans|Animals|Mice|NR3B NMDA receptor|*Receptors, N-Methyl-D-Aspartate|*Motoneurons|Maze Learning|Behavior, Animal|*Neurons, Efferent|*Phenotypes|Brain|Motor Activity|Anxiety 21 GRIN3B 17687115 Neurology 2007 10.1212/01.wnl.0000271078.51280.17 8 1 0 31 Amyotrophic Lateral Sclerosis 2, Juvenile|*Alleles|Amyotrophic Lateral Sclerosis|*Motoneuron|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Superoxide Dismutase-1|Genotype|Superoxide Dismutase|Receptors, N-Methyl-D-Aspartate|*Neurons, Efferent 21 HMGN3 17211498 Int J Med Sci 2007 PMC1752234 10.7150/ijms.4.28 4 14 0 72 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*HepG2 Cells|*Ethanol|cDNA Microarrays|Gene Expression Profiling|Transcription Factors|Gene Expression Regulation, Neoplastic|*Genomics|Gene Expression|Signal Transduction|Up-Regulation|ANK3 protein, human|Ankyrins 28 HTATSF1 17991777 Proc. Natl. Acad. Sci. U.S.A. 2007 PMC2084326 10.1073/pnas.0705856104 44 1 6 139 Humans|Animals|*RNA, Viral|*Saccharomyces cerevisiae|*Orthomyxoviridae|*Replicon|Nucleoprotein|Virus Replication|RNA Polymerases|*Yeast, Dried|Genome, Viral|Influenza A virus|Transcription, Genetic|Influenza|Cell Line 26 HTATSF1 17690704 Leukemia 2007 10.1038/sj.leu.2404879 15 0 0 139 Male|Female|Child|Humans|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|*Comparative Genomic Hybridization|In Situ Hybridization, Fluorescence|*Incidence|Chromosome Xq duplication syndrome|*Sex Chromosome Aberrations|*Chromosomes, Human, X|*Trisomy|Proto-Oncogene Proteins c-ets|Precursor Cell Lymphoblastic Leukemia-Lymphoma|*Sex Chromosome Disorders|Translocation, Genetic|Oncogene Proteins, Fusion|Chromosome Aberrations|Gene Expression Profiling|Repressor Proteins|Rap2C protein, human 26 hus1b 18156970 Int. J. Gynecol. Pathol. 2007 10.1097/pgp.0b013e31812dfaef 5 0 0 18 Humans|Female|*Prognosis|*Ovarian Neoplasms|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|bcl-2-Associated X Protein|Immunohistochemistry|Tumor Suppressor Protein p53|Apoptosis|Biomarkers, Tumor|Neoplasm Staging|Kaplan-Meier Estimate|*Cell Cycle Checkpoints|DNA Damage 32 hus1b 17855402 Nucleic Acids Res. 2007 PMC2094074 10.1093/nar/gkm678 34 38 2 18 Humans|LIG4 protein, human|*DNA Ligase ATP|rad9 protein|Cell Cycle Proteins|DNA Glycosylase|xeroderma pigmentosum group F protein|*DNA-Binding Proteins|Exonucleases|DNA Repair|Thymine DNA Glycosylase|RRAD protein, human|*ras Proteins|Cell Nucleus 32 IMPG1 17760704 Vet Ophthalmol 2007 10.1111/j.1463-5224.2007.00549.x 1 1 0 26 Humans|Animals|*Macaca mulatta|*Retinal Drusen|Maculopathy, Age-Related|Monkey Diseases|Genotype|Haplotype|Retina|Puerto Rico|Germany 29 IMPG1 17200664 Mol. Vis. 2007 24 0 0 26 Humans|*Retinal Ganglion Cells|*Transcriptome|*Retina|Oligonucleotide Array Sequence Analysis|Eye Proteins|Gene Expression Profiling|Glaucoma|RNA, Messenger 29 INSL4 18060948 Am. J. Obstet. Gynecol. 2007 10.1016/j.ajog.2007.04.018 2 0 0 17 Pregnancy|Female|Humans|*Placenta|Pre-Eclampsia|*Pregnancy Complications|Fetal Growth Retardation|Enzyme-Linked Immunosorbent Assay|*Somatomedins|Peptides 45 INSL4 18035692 Verh Dtsch Ges Pathol 2007 1 4 0 17 Female|Pregnancy|Humans|ERBB2 protein, human|*Receptor, ErbB-2|*Signal Transduction|*Phosphorylation|RNA, Small Interfering|Cell Line, Tumor|*Oncogenes|RNA, Messenger|*Somatomedins|*Placenta 45 INSL4 17610369 Stem Cells Dev. 2007 10.1089/scd.2006.0013 10 0 0 17 Humans|Female|Pregnancy|*Trophoblasts|*Human Embryonic Stem Cells|*Hematopoiesis|Cell Differentiation|Embryonic Stem Cells|Endoderm|Cell Line|Hemangioblast|Platelet Endothelial Cell Adhesion Molecule 1|POU5F1 protein, human|Octamer Transcription Factor-3|Chorionic Gonadotropin, beta Subunit, Human|Genes, Homeobox|cadherin 5|Cadherins|Culture Media|Gene Expression|Antigens, CD 45 ITM2C 17873332 Endocrine 2007 10.1007/s12020-007-0027-6 2 2 0 80 Humans|Male|Mice|Animals|*Integral Membrane Protein|Epididymis|Vas Deferens|Testis|Sexual Maturation|Orchiectomy|In Situ Hybridization|Testosterone|Seminiferous Tubules|*Reproduction|Leydig Cells|TYRP1 protein, human|Membrane Glycoproteins|mRNA|ITM2A protein, human 27 KLF16 17480121 PLoS Genet. 2007 PMC1865561 10.1371/journal.pgen.0030065 40 7 1 93 Humans|Mice|Animals|*Transcription Factor|CpG Island|Genomic Imprinting|DNA Methylation|DNA methyltransferase 3A|DNA (Cytosine-5-)-Methyltransferases|Epigenesis, Genetic|Chromosome|Allele|Chromatin Immunoprecipitation|Chromosome Mapping|Gene Expression Regulation, Developmental|Mice, Knockout|KLF14 protein, human|Sp Transcription Factors|Klf16 protein, mouse|Kruppel-Like Transcription Factors|Klf14 protein, mouse 26 KLK9 17459052 Cancer Sci. 2007 10.1111/j.1349-7006.2007.00495.x 11 1 0 20 *Urinary Bladder Neoplasms|*Urinary Bladder|Comparative Genomic Hybridization|*Carcinoma|Oligonucleotide Array Sequence Analysis|Kallikrein|mRNA|*Epithelial Cells 36 KLK9 17366701 Genes Funct. 2007 10.1046/j.1365-4624.1997.00027.x 3 0 0 20 Rats|Animals|Mice|*Tissue Kallikreins|Kallikrein|*Gene Expression Regulation|Base Sequence|Gene Expression|Polymerase Chain Reaction|RNA, Messenger|Submandibular Gland|Multigene Family|Mice, Transgenic 36 KLRC4 18006695 Blood 2007 10.1182/blood-2007-08-110130 9 0 0 16 Humans|*Polymorphism, Single Nucleotide|*Prognosis|Immunoglobulin Variable Region|Leukemia, Lymphocytic, Chronic, B-Cell|Immunoglobulin Heavy Chains|fludarabine|Vidarabine|Chlorambucil|Genotype|Mutations|Kaplan-Meier Estimate|Cyclophosphamide 24 LGALS12 17363919 J. Invest. Dermatol. 2007 10.1038/sj.jid.5700743 21 0 2 461 Humans|*Sebaceous Glands|*Lipogenesis|*Sterol Regulatory Element Binding Protein 1|RETN protein, human|*Resistin|*Galectin|*Factor 12|Cell Differentiation|*Epithelial Cells|mRNA|Skin|Lipid Metabolism|CCAAT-Enhancer-Binding Protein-alpha|Cell Line, Transformed|Cell Line|Gene Expression 24 LSG1 17761675 J. Biol. Chem. 2007 10.1074/jbc.M705057200 22 2 1 94 *Saccharomyces cerevisiae|*Ribosomal Protein|Saccharomyces cerevisiae Proteins|Ribosome|*Ribosomal Protein L10|*Yeast, Dried|*DNA Mutational Analysis|Export, Nuclear|Amino Acid Sequence|Conserved Sequence|Mutations|Sequence Alignment|Mutant Proteins|RPL10 protein, S cerevisiae 26 MIDN 17425751 Clin Transplant 2007 10.1111/j.1399-0012.2006.00631.x 0 0 0 245 Humans|*Quality of Life|*Kidney Transplantation|Renal Dialysis|*Living Donors|*Tissue and Organ Harvesting|Nephrectomy|*Kidney|Laparoscopy|*Surgical Wound 23 ncln 17261586 J. Biol. Chem. 2007 10.1074/jbc.M611033200 6 1 0 65 gamma-Secretase|Alzheimer Disease|Membrane Glycoproteins|Membrane Proteins|*Transforming Growth Factor beta|Cell Membrane|Signal Transduction 21 ncln 17249659 Inorg Chem 2007 10.1021/ic061811s 2 0 0 65 *X-Ray Diffraction|*Tin|*NMR Spectroscopy|Organotin Compounds|Molecular Structure|Crystallography, X-Ray|*Magnetic Resonance Imaging|Models, Molecular|Hydrogen Bonding|Chlorine|Dimerization|Hydrogen|Polymers|Chalcogens 21 NHLH1 17652135 RNA 2007 PMC1950760 10.1261/rna.659307 70 0 2 132 Male|Mice|Animals|*Piwi-Interacting RNA|*Methylation|methylcobalamin-coenzyme M methyltransferase|*Methyltransferases|Argonaute Proteins|RNA, Micro|Testis|Germ Cells|Archaeal Proteins 43 NHLH1 17573818 J. Neurochem. 2007 10.1111/j.1471-4159.2007.04694.x 13 0 0 132 Pregnancy|Female|Mice|Animals|*Neurons|Paired Box Transcription Factors|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Rhombencephalon|Eye Proteins|Repressor Proteins|PAX6 Transcription Factor|Cerebellum|Cell Movement|Gene Expression Regulation, Developmental|*Raphe Nuclei|Medulla Oblongata|Pons|Receptor, Netrin 43 OLFML3 17655932 Neurotoxicology 2007 10.1016/j.neuro.2007.05.010 1 0 0 48 Animals|Mice|Rats|*Olfactory Bulb|2,6-dichlorophenyl methylsulfone|Olfactory Mucosa|Benzene Derivatives|*Sulfones|*Smell|Glial Fibrillary Acidic Protein|dimethyl sulfone|*Dimethyl Sulfoxide|*Isomerism|Injections, Intraperitoneal|Gliosis|cDNA Arrays|Brain|Ncor1 protein, rat|Nuclear Receptor Co-Repressor 1 21 OTOP1 17606897 Proc. Natl. Acad. Sci. U.S.A. 2007 PMC1924595 10.1073/pnas.0705182104 16 2 0 24 Animals|*Calcium|Calcium Signaling|Receptors, Purinergic P2|Receptors, Purinergic P2Y|Uridine Triphosphate|Purinergic P2 Receptor Agonists|Adenosine Triphosphate|Adenosine Diphosphate|*Calcium, Dietary|Cells, Cultured|Endoplasmic Reticulum|Calcium Carbonate|Otoconia 23 PCDH11Y 17671842 Chromosome Res. 2007 PMC2779385 10.1007/s10577-007-1153-y 3 0 1 45 Humans|Male|Animals|Female|Gorilla gorilla|Chromosomes, Human, Y|Chromosomes, Human, X|Primate|*Chromosome Structures|Pan troglodytes|In Situ Hybridization, Fluorescence|X-Inactivation|Evolution, Molecular|Cadherins 24 PDE3B signalling 17884339 Cell. Signal. 2007 10.1016/j.cellsig.2007.08.005 19 0 0 0 Humans|*Protein Kinase A|*Cyclic Nucleotide Phosphodiesterases, Type 4|*Cell Adhesion|HEK293 Cells|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Cyclic AMP|Signal Transduction|Phosphodiesterase 3B|Guanine Nucleotide Exchange Factors|Colforsin|Phosphodiesterase Inhibitors 21 PDE3B signalling 17324123 Biochem. J. 2007 PMC1868803 10.1042/BJ20060960 22 4 2 0 Mice|Animals|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Cyclic Nucleotide Phosphodiesterases, Type 3|Phosphatidylinositol 3-Kinases|B-insulin|*Insulin|3',5'-Cyclic-AMP Phosphodiesterases|Phosphorylation|Lipolysis|Adipocyte|3T3-L1|Signal Transduction|Enzyme Activation|Cyclic AMP|Golgi Apparatus|*Biotin|Protein Transport|Endoplasmic Reticulum 21 PDE3B signalling 17320989 Biochim. Biophys. Acta 2007 10.1016/j.bbamcr.2007.01.010 14 4 1 0 Animals|Rats|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Phosphorylation|*Adipocyte|AKT1 protein, human|Protein Kinase B|3',5'-Cyclic-AMP Phosphodiesterases|Signal Transduction|Insulin|Enzyme Activation|Cyclic AMP-Dependent Protein Kinases|Cyclic AMP|*Hepatocyte 21 PDE3B signalling 17220874 Nature 2007 10.1038/nature05543 386 1 20 0 Mice|Animals|T-Cells, Regulatory|*Lymphocyte Activation|Forkhead Transcription Factors|Interleukine 2|Gene Expression Regulation|Cell Differentiation|Signal Transduction|*Hematopoiesis|CD4-Positive T-Lymphocytes|Foxp3 protein, mouse 21 pkd1l1 18084325 Oncogene 2007 PMC2423006 10.1038/sj.onc.1210993 27 1 1 17 Humans|*Translocation, Genetic|*Oncogenes|Oligonucleotide Arrays|*MCF-7 Cells|Chromosome Breakage|Chromosome Painting|Chromosome Aberrations|Chromosome Mapping|In Situ Hybridization, Fluorescence|Bacterial Artificial Chromosome|Cell Line, Tumor|Genes, Tumor Suppressor|Nucleic Acid Hybridization|PKD1L1 protein, human|Membrane Proteins 20 PLAC4 17664418 Proc. Natl. Acad. Sci. U.S.A. 2007 PMC1934923 10.1073/pnas.0705765104 94 0 11 0 Female|Pregnancy|Humans|Computer Simulation|*Aneuploidy|Prenatal Diagnosis|*Fetuses|Trisomy 21|Trisomy|*Polymerase Chain Reaction|Amniocentesis|*Prenatal Care|DNA|RNA|Sequence Analysis, DNA|mRNA|Polymorphism, Single Nucleotide|*Chromosome 22 PLAC4 17206148 Nat. Med. 2007 10.1038/nm1530 65 0 2 0 Female|Pregnancy|Humans|*Alleles|*RNA|*Aneuploidy|Prenatal Diagnosis|Trisomy|Trisomy 21|*Placenta|Single Nucleotide Polymorphism|*Plasma|Fetus|mRNA|Genotype|Polymerase Chain Reaction|*Chromosome 22 POU6F1 17933456 Mol. Cell. Endocrinol. 2007 10.1016/j.mce.2007.09.002 4 4 0 30 Humans|HEK293 Cells|*DNA-Binding Proteins|*Transcription Factors|Pituitary Gland|*Gene Expression|Prolactin|Promoter Regions, Genetic|Gene Expression Regulation|Growth Hormone|Reporter Gene|mRNA|Transfection 34 POU6F1 17924165 Mamm. Genome 2007 PMC2042028 10.1007/s00335-007-9059-8 7 0 2 30 Humans|Animals|Mice|*Sodium Channel|Exons|NAV1.6 Voltage-Gated Sodium Channel|Nerve Tissue Proteins|Base Sequence|Mice, Transgenic|Alternative Splicing|Sequences, Conserved|Neurons|Purkinje Cells|Brain|Systems, Peripheral Nervous|Regulatory Sequences, Nucleic Acid|Promoter Regions, Genetic|Alleles|Mutations|SCN8A protein, human|Scn8a protein, mouse 34 POU6F1 17494089 Am. J. Physiol. Renal Physiol. 2007 10.1152/ajprenal.00416.2006 68 0 4 30 Mice|Animals|*Wnt Signaling Pathway|WNT2B protein, human|Wnt Proteins|beta Catenin|Mesenchyme|Kidney|Glycoproteins|*Organogenesis|Ureter|Gene Expression Regulation, Developmental|Epithelial Cells|Kidney Tubules 34 PPP1R3A 17555403 Biochem. J. 2007 PMC1925244 10.1042/BJ20061572 9 3 1 909 Humans|*Glycogen|*Protein Phosphatase 1|Glycogen Synthase Kinase 3|Glycogen Synthase|Glycogen Phosphorylase|Glucose|Myotube|Insulin|Muscle, Skeletal|Phosphorylation|Carrier Proteins|Protein Subunits|*Carbohydrate Metabolism|Insulin, Regular, Human|PPP1R3A protein, human|Phosphoprotein Phosphatases 40 PTPRCAP 17428310 Immunology 2007 PMC2265975 10.1111/j.1365-2567.2007.02602.x 9 5 1 34 Mice|Animals|*CD4-Positive T-Lymphocytes|*T Cell Receptor|PTPRC protein, human|*Leukocyte Common Antigens|Lymphocyte Activation|Lymphocyte Specific Protein Tyrosine Kinase p56(lck)|CD3 Complex|TYRP1 protein, human|*Membrane Glycoproteins|Signal Transduction|Interleukin-2|Phosphorylation|Protein Tyrosine Phosphatases 48 PTPRCAP 17397547 BMC Physiol. 2007 PMC1853107 10.1186/1472-6793-7-3 16 13 0 34 Escherichia coli|*Inflammation|Bladder, Urinary|Cystitis|Receptor, PAR-1|Receptor, PAR-2|Lipopolysaccharides|Administration, Intravesical|Substance P|Tumor Necrosis Factor-alpha|Signal Transduction Pathway|Granulocyte|Antigen 48 Resp18 17951542 J. Endocrinol. 2007 10.1677/JOE-07-0252 10 1 1 423 Animals|Rats|Humans|Mice|regulated endocrine secretory protein 18|*Secretory Vesicles|*NOD Mice|*Nerve Tissue Proteins|Pancreatic Islets|Receptor-Like Protein Tyrosine Phosphatases, Class 8|Insulin Secretion|Insulin|Pancreas|Insulin-Secreting Cells|Exocytosis|Membrane Proteins|Glucose|*Pancreas, Exocrine|Microscopy, Immunoelectron 23 RTTN 17551791 Mamm. Genome 2007 10.1007/s00335-007-9023-7 7 0 0 72 Mice|Animals|*Mutation|Body Patterning|Transcription Factors|Left-Right Determination Factors|Nodal Protein|Homeodomain Proteins|Nuclear Proteins|Trans-Activators|Notochords|Gene Expression Regulation, Developmental|Transforming Growth Factor beta|Homozygote 21 SAMSN1 18074101 J. Hum. Genet. 2007 10.1007/s10038-007-0229-z 1 0 0 51 Humans|Male|Child|*Down Syndrome|Comparative Genomic Hybridization|Translocation, Genetic|Isochromosome|In Situ Hybridization, Fluorescence|*Gene Dosage|Centromere|Chromosome 21|Fathers|SAMSN1 protein, human|Adaptor Proteins, Vesicular Transport|TPTE protein, human|Membrane Proteins|PTEN Phosphohydrolase 25 SBSN 17868834 Arthroscopy 2007 10.1016/j.arthro.2007.03.099 16 0 0 57 *Prevalence|Hamstring Tendons|Anterior Cruciate Ligament Reconstruction|*Hamstring Muscles|Tissue and Organ Harvesting|Peripheral Nerve Injuries|*Thigh 23 SCAMP2 17723134 J. Thromb. Haemost. 2007 10.1111/j.1538-7836.2007.02690.x 0 0 1 316 *Proteomics|*Mass Spectrometry|Platelets|Proteome|*Secretory Vesicles|Organelles 26 SCAMP2 17713930 Biochemistry 2007 10.1021/bi701121j 19 2 0 316 Animals|Rats|Humans|*Phosphatidylinositol|*Secretory Vesicles|Exocytosis|Membrane Fusion|Membrane Proteins|Cell Membrane|Carrier Proteins|Vesicular Transport Proteins|PC12 Cells|Protein Binding|Calcium|Protein Structure, Tertiary|Amino Acid Sequence|Transfection|Biological Transport 26 SEZ6L 18158559 Lab. Invest. 2007 10.1038/labinvest.3700707 47 4 5 15 Humans|Helicobacter Infections|*DNA Methylation|Helicobacter pylori|CpG Island|*Stomach Neoplasms|Gastric Mucosa|Gastritis|DNA, Neoplasm|TWIST1 protein, human|Nuclear Proteins|SFRP4 protein, human|Proto-Oncogene Proteins|Twist-Related Protein 1|DLEC1 protein, human|Tumor Suppressor Proteins|HOXA10 protein, human|Homeobox A10 Proteins 21 SEZ6L 17804757 Cancer Res. 2007 10.1158/0008-5472.CAN-06-4784 9 0 0 15 Male|Humans|Female|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Pilot Projects|SNPs|Small Cell Lung Carcinoma|Genetic Predisposition to Disease|Case-Control Studies|Asian Continental Ancestry Group|Genotype|Allele|Homozygotes|Gene Expression|*Seizure|United Kingdom 21 SPANXA1 17406683 PLoS ONE 2007 PMC1831492 10.1371/journal.pone.0000359 19 5 1 37 Male|Animals|*Sperm|Spermatids|Amino Acid Sequence|Acrosome|X Chromosome|Neoplasm Proteins|Promoter Regions, Genetic|Nuclear Proteins|Spermatogenesis|Antigens, Neoplasm|Nuclear Envelope|Genetic Evolution|Hominidae|Sequence Homology, Amino Acid|*Biological Evolution|Testis|Cell Nucleus 27 SPANXA1 17373721 Prostate 2007 10.1002/pros.20561 13 0 2 37 Humans|Male|*Prostate Cancer|Genetic Linkage|Chromosome Mapping|*DNA Mutational Analysis|Nuclear Proteins|*Genes, X-Linked|Chromosomes, Human, X|Genetic Predisposition to Disease 27 SPANXA1 17342728 Mol. Reprod. Dev. 2007 10.1002/mrd.20651 1 0 0 37 Male|Mice|Humans|Animals|Amino Acid Sequence|Proteins|Spermatids|Genome|Multigene Family|Base Sequence|Sequence Homology, Amino Acid|Evolution, Molecular|Chromosome Mapping|Phylogeny|Exons|Testis|Promoter Regions, Genetic|VCX protein, human|Nuclear Proteins 27 SPANXA1 17204091 Hum. Cell 2007 10.1111/j.1749-0774.2006.00014.x 3 0 0 37 Humans|Male|Testicular Germ Cell Tumor|*mRNA|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Seminoma|Gene Expression Regulation, Neoplastic|Chromosomes, Human, X|Tumorigenesis 27 SVOP 17973810 Acta Psychiatr Scand Suppl 2007 10.1111/j.1600-0447.2007.01093.x 11 0 0 115 Humans|*Patient Satisfaction|*Mental Health|Community Mental Health Centers|Community Mental Health Services|Psychotic Disorders 26 TBPL1 17570761 DNA Cell Biol. 2007 10.1089/dna.2006.0527 2 0 0 1191 Humans|Mice|Animals|Rats|*TATA-Box Binding Protein|Drosophila melanogaster|Phylogeny|TATA Box Binding Protein-Like Proteins|Transcription Factors|TATA Box|DNA-Binding Proteins|Transcription, Genetic|Amino Acid Sequence|TATA-Binding Protein Associated Factors|*Genomics|Promoter Regions, Genetic|Sequence Homology, Amino Acid|Genome|TBPL1 protein, human 28 TCF15 17937396 Dev. Dyn. 2007 10.1002/dvdy.21342 18 0 0 58 Mice|Animals|Prospective Studies|Somites|Mesoderm|Body Patterning|Transcription Factors|Receptors, Notch|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Mammalian Embryos|Signal Transduction|Repressor Proteins|*Embryonic Development|Biological Clocks|In Situ Hybridization 39 TCF15 17477400 Dev. Dyn. 2007 10.1002/dvdy.21178 5 0 0 58 Mice|Animals|Somites|Basic Helix-Loop-Helix Transcription Factors|Mesoderm|PAX1 transcription factor|Paired Box Transcription Factors|Helix-Loop-Helix Motifs|Body Patterning|Gene Expression Regulation, Developmental|Myogenesis|Cell Lineage|Embryonic Development|Embryo, Mammalian|Cell Differentiation 39 TEX19 18096721 Stem Cells 2007 10.1634/stemcells.2007-0772 19 0 2 48 Humans|Male|Mice|Rats|Animals|*Pluripotent Stem Cells|*Germ Line|POU5F1 protein, human|Octamer Transcription Factor-3|Embryonic Stem Cells|Cell Differentiation|Cell Lineage|Blastocyst|Embryo, Mammalian|Nuclear Proteins|Gene Expression Regulation, Developmental|Testis|*Mammals|Cell Line|Gene Expression Profiling|Tex19 protein, human|Tex19 protein, mouse 20 TLE6 17624551 Dev. Genes Evol. 2007 10.1007/s00427-007-0167-y 8 0 0 17 Animals|Phylogeny|Drosophila|Basic Helix-Loop-Helix Transcription Factors|Corepressor Proteins|Repressor Proteins|Transcription Factors|Genetic Evolution|*Chromosome Structures|groucho protein, Drosophila 23 TTC12 17943972 Genes Chromosomes Cancer 2007 10.1002/gcc.20504 16 0 1 11 Humans|Male|Young Adult|Male Germ Cell Tumor|*Tumors, Germ Cell|*Testicular Neoplasms|Testicular Germ Cell Tumor|Seminoma|Embryonal Carcinoma|Yolk Sac Tumors|*Genomics|Oligonucleotide Array Sequence Analysis|Germinoma|Gene Expression Profiling|Oncogenes|Gene Expression Regulation, Neoplastic|DNA, Complementary|Cell Differentiation|Evolution, Molecular|SPRY2 protein, human|Membrane Proteins 24 ZC3H12D 17210687 Cancer Res. 2007 PMC3461257 10.1158/0008-5472.CAN-06-2723 12 0 0 498 Humans|Mice|Animals|Genes, Tumor Suppressor|Lung Cancer|Allele|Loss of Heterozygosity|Adenocarcinoma|Base Sequence|Chromosome Mapping|Tumor Suppressor Proteins|*Human Chromosome|DNA Primers|Heterozygote|Lung|Nude Mouse 20 ACTBP2 16838164 Int. J. Legal Med. 2006 10.1007/s00414-006-0091-0 1 0 0 0 Humans|*Mutation Rate|Afghanistan|*Frequencies, Allele|Short Tandem Repeat|Genetics, Population|DNA Fingerprinting|Alleles|*Meiosis|Mutations|Immigrants|Probability 67 ACTBP2 16518431 Bone Marrow Transplant. 2006 10.1038/sj.bmt.1705317 4 0 0 0 Humans|*Chimerism|*Bone Marrow Transplantation|Transplantation, Homologous|Transplantation Chimera|Hematopoietic Stem Cell Transplantation|Genetic Markers|Polymerase Chain Reaction|Donor|Alleles|Graft Survival|Amelogenin|*Algorithm 67 ADAM7 16407499 Biol. Reprod. 2006 10.1095/biolreprod.105.048892 21 0 2 20 Male|Mice|Animals|Phylogeny|Epididymis|Fertilins|Sperm|Testis|Fertilization|ADAM Proteins|Membrane Glycoproteins|*Reproduction|Knockout Mouse|Cell Membrane|Adam7 protein, mouse|Membrane Proteins|Adam3 protein, mouse 24 AGAP1 16413266 Meth. Enzymol. 2006 10.1016/S0076-6879(05)04015-2 12 2 0 202 *GTPase-Activating Proteins|ADP-Ribosylation Factors|ADP-Ribosylation Factor 1|Guanosine Triphosphate|GTP-Binding Proteins|Protein Transport|Hydrolysis|Actin 25 ATL2 17166839 J. Biol. Chem. 2006 10.1074/jbc.M608792200 29 2 1 95 *Arabidopsis|*Fatty Acid Synthase Type II|*Pathogen-Associated Molecular Pattern Molecules|Gene Expression Regulation, Plant|Plants, Genetically Modified|Plant Diseases|Bacterial Proteins|Signal Transduction|*Lipids|FLS2 protein, Arabidopsis|Protein Kinases|Arabidopsis Proteins|ATL2 protein, Arabidopsis|DNA-Binding Proteins 23 ATL2 16897085 Curr. Genet. 2006 10.1007/s00294-006-0093-y 0 0 0 95 *Saccharomyces cerevisiae|*Arabidopsis|*Ubiquitin|*Ubiquitination|Ubiquitin-Conjugating Enzymes|Saccharomyces cerevisiae Proteins|Ubiquitin-Protein Ligases|Arabidopsis Proteins|Mutations|ATL2 protein, Arabidopsis|DNA-Binding Proteins|UBP14 protein, Arabidopsis|Endopeptidases|DOA4 protein, S cerevisiae|Ubiquitin Thiolesterase|Endosomal Sorting Complexes Required for Transport|UBP6 protein, S cerevisiae|Ubp15 protein, S cerevisiae 23 CST8 17146919 Zhonghua Nan Ke Xue 2006 0 0 0 190 Humans|Male|Rats|Animals|*Epididymis|*Testis|*Varicocele|*Spermatogenesis|*Cystatins 31 CST8 16837735 J. Androl. 2006 10.2164/jandrol.106.000331 2 4 0 190 Humans|Male|Mice|Animals|*Gn-RH|*Androgens|*mRNA|*Gonadotrophs|Luteinizing Hormone|*Pituitary Hormones, Anterior|Pituitary Gland|Dihydrotestosterone|Testosterone|LH beta|Orchiectomy|*Proteins|Oestradiol|Hormone Antagonists|iturelix|Oligopeptides 31 CST8 16720722 J. Mol. Endocrinol. 2006 10.1677/jme.1.01980 6 10 1 190 Humans|Rats|Swine|Animals|*Somatostatin|cortistatin|cortistatin-8|*Neuropeptide|Growth Hormone|Growth Hormone-Releasing Hormone|Receptors, Pituitary Hormone-Regulating Hormone|Somatotrophs|Human Growth Hormone|Ghrelin|Receptors, Ghrelin|Receptors, Somatostatin|Pituitary Gland|Signal Transduction 31 CST8 16420281 J. Neuroendocrinol. 2006 10.1111/j.1365-2826.2005.01391.x 3 0 0 190 Rats|Animals|*GHS-R1A|*Ghrelin|*Gastric Acid|cortistatin|Neuropeptide|Somatostatin|growth hormone releasing hexapeptide|Oligopeptides|Receptors, Somatostatin|Human Growth Hormone|Ligands|*Biological Transport|somatotropin-binding protein 31 CST8 16394217 Biol. Reprod. 2006 10.1095/biolreprod.105.044354 7 0 0 190 Rats|Animals|Male|*Epididymis|transcription factor PEA3|*Transcription Factor|*Gene Expression Regulation|Testis|Promoter Regions, Genetic|mRNA|selenium-independent glutathione peroxidase|Glutathione Peroxidase|Electroporation|ETV4 protein, rat|Trans-Activators 31 DAZ3 16963411 Yi Chuan 2006 10.1360/yc-006-1057 0 0 0 1 Humans|Male|*Gene Deletion|*Oligospermia|*Sperm Injections, Intracytoplasmic|Deleted in Azoospermia 1 Protein|Infertility, Male|Azoospermia|Chromosomes, Human, Y|Spermatogenesis|Restriction Fragment Length Polymorphism|RNA-Binding Proteins|Gene Frequency|Chromosome Mapping|Polymerase Chain Reaction|Spermatozoa 20 DAZ3 16596261 Int. J. Mol. Med. 2006 1 0 0 1 20 DDX10 17116492 Cancer Genet. Cytogenet. 2006 10.1016/j.cancergencyto.2006.07.002 5 0 0 68 Humans|Child|nuclear pore complex protein 98|In Situ Hybridization, Fluorescence|*Chromosome Inversion|Nuclear Pore Complex Proteins|Translocation, Genetic|Oncogene Proteins, Fusion|DDX10 protein, human|DEAD-box RNA Helicases|Base Sequence|Amino Acid Sequence|Leukemia, Myeloid, Acute 29 DDX10 16467868 Leukemia 2006 10.1038/sj.leu.2404130 29 0 1 68 Humans|nuclear pore complex protein 98|In Situ Hybridization, Fluorescence|Nuclear Pore Complex Proteins|Translocation, Genetic|*Malignancies, Hematopoietic|Base Sequence|Oncogene Proteins, Fusion|Amino Acid Sequence|Homeodomain Proteins|DDX10 protein, human|DEAD-box RNA Helicases|RAP1GDS1 protein, human|Guanine Nucleotide Exchange Factors 29 DGCR2 16783572 Hum. Genet. 2006 10.1007/s00439-006-0195-0 12 0 0 182 Humans|Rats|Animals|*Schizophrenia|Linkage Disequilibrium|Catechol O-Methyltransferase|Genetic Predisposition to Disease|Antipsychotic Drugs|Polymorphism, Single Nucleotide|Gene Frequency|Allele|Haplotypes|Dorsolateral Prefrontal Cortex|Case-Control Studies|Jews 22 DNAJC14 16572726 Cell Stress Chaperones 2006 PMC1400611 10.1379/csc-137r.1 12 0 1 65 Humans|Animals|*Ciona intestinalis|*Heat-Shock Proteins 70|*Molecular Chaperones|Genome|Evolution, Molecular|Vertebrates|Phylogeny|Databases, Genetic|BAG3 protein, human|Adaptor Proteins, Signal Transducing|Apoptosis Regulatory Proteins|DNAJC14 protein, human|Fetal Proteins|BAG2 protein, human|BAG5 protein, human 20 EPB41L4B 16927306 Prostate 2006 10.1002/pros.20474 9 2 0 90 Humans|Male|Neoplasm Recurrence, Local|*Prostate Cancer|Prostate|Prostatectomy|Gene Expression Regulation, Neoplastic|FGFR4 protein, human|Receptor, Fibroblast Growth Factor, Type 4|Adenocarcinoma|Cell Movement|Androgens|Tumor Cells, Cultured|Disease Progression 23 EVX2 16399081 Dev. Cell 2006 10.1016/j.devcel.2005.11.014 72 0 3 14 Mice|Animals|Phylogeny|Genes, Homeobox|Homeodomain Proteins|Limb Buds|Body Patterning|Limb|Gene Expression Regulation, Developmental|Morphogenesis|Transcription Factors|*Organogenesis 33 FOXN2 16525939 Int. J. Dev. Biol. 2006 10.1387/ijdb.052126ms 10 0 3 138 28 GBX1 17067785 Mech. Dev. 2006 10.1016/j.mod.2006.08.007 4 0 0 17 Animals|Mice|*Zebrafish|Hindbrain|Zebrafish Proteins|Mesencephalon|Genes, Homeobox|*Regulatory Sequences, Nucleic Acid|Gene Expression Regulation, Developmental|Body Patterning|Transcription Factors|Otx Transcription Factors|*Gene Expression|PAX2 Transcription Factor|Conserved Sequence|Wnt Proteins|Promoter Regions, Genetic|Reporter Gene|Morphogenesis|Gbx2 protein, mouse 34 GBX1 16597639 Mol. Hum. Reprod. 2006 10.1093/molehr/gal035 21 0 2 17 Male|Female|Humans|Mice|Animals|*DNA, Complementary|*Ovarian Follicles|*Oocytes|Homeo Box Genes|Oogenesis|HOXA5 protein, human|Homeodomain Proteins|Ovary|Gene Expression Regulation, Developmental|Transcription Factors|Embryonic Development|Granulosa Cells|Metaphase|Transcript Expression Analysis|Cloning, Molecular|HOXA10 protein, human|Homeobox A10 Proteins|HOXA4 protein, human 34 GLIPR2 17055234 Matrix Biol. 2006 10.1016/j.matbio.2006.09.005 5 1 0 52 Mice|Animals|*Epithelial-Mesenchymal Transition|*Fibrosis|*Kidney Diseases|Kidney|Kidney Tubules|Cells, Epithelial|Transforming Growth Factor beta1|Mesoderm|Cell Differentiation|Cadherins|pathogenesis-related proteins, plant|*Plant Proteins|Actins|*Urinary Tract|GLIPR-2 protein, mouse|Proteins 21 GLIPR2 16755518 J. Pathol. 2006 10.1002/path.2008 21 1 2 52 *Hedgehog Proteins|*Chondrosarcoma|Osteochondroma|*Signal Transduction|PTHLH protein, human|Parathyroid Hormone-Related Protein|Transforming Growth Factor beta|Multiple Osteochondromas|Bone Neoplasms|*Disease Progression|Growth Plate|Gene Expression Regulation, Neoplastic|N-Acetylglucosaminyltransferases|Cell Transformation, Neoplastic|RNA, Messenger 21 HMG20B 17085781 J. Mol. Neurosci. 2006 10.1385/JMN:29:3:227 37 0 4 74 22 HMGN3 17172658 Mol. Biotechnol. 2006 10.1385/mb:34:2:125 26 0 3 72 Cricetinae|Animals|*Cricetulus|*CHO Cells|*Proteome|*Transcriptome|Proteomics|*Gene Expression Profiling|cDNA Microarray|mRNA|Cell Cycle|Genomics|Upregulation|Downregulation 28 KLK9 16829021 Genomics 2006 10.1016/j.ygeno.2006.06.001 8 0 1 20 Humans|Dogs|Rats|Animals|Mice|Swine|*Phylogeny|*Bayes Theorem|kallikrein 5, human|*Kallikrein|KLK15 protein, human|*Mammals|Genome|Chromosome Mapping|Base Sequence|Pan troglodytes|*In Silico|KLK6 protein, human|KLK13 protein, human|KLK10 protein, human|KLK12 protein, human 36 KLK9 16800734 Biol. Chem. 2006 10.1515/BC.2006.092 3 0 0 20 Male|Cricetinae|Animals|Humans|Rabbits|*Tissue Kallikreins|Escherichia coli|Cricetulus|kallikrein-related peptidase 3, human|*Kallikrein B'|Prostate Specific Antigen|*Recombinant Proteins|Prostate Cancer|*Antibodies|Western Blots|Amino Acid Sequence|cDNA|mRNA|Mass Spectrometry|Semen 36 MIDN 17130777 Transplantation 2006 10.1097/01.tp.0000239312.45050.05 6 0 2 245 Humans|*Prospective Studies|Quality of Life|*Tissue and Organ Harvesting|*Laparoscopy|Nephrectomy|Living Donors|Kidney Transplantation|*Kidney|Fatigue|*Surgical Wound 23 MIDN 16891649 Nephrol. Dial. Transplant. 2006 10.1093/ndt/gfl158 3 0 0 245 Humans|*Nephrectomy|*Retroperitoneal Space|*Tissue and Organ Harvesting|Living Donors|*Kidney|Kidney Transplantation|Laparoscopy|*Abdomen|*Surgical Wound|Length of Stay|Postoperative Period 23 MIDN 16785245 Radiat Prot Dosimetry 2006 10.1093/rpd/nci601 0 0 0 245 Humans|*Spacecraft|Cosmic Radiation|Thermoluminescent Dosimetry|Radiation Protection|Space Exploration|Radiation Dosage|Dose-Response Relationship, Radiation|Astronauts|Relative Biological Effectiveness|Sensitivity and Specificity|Occupational Exposure|Equipment Failure Analysis|Reproducibility of Results|Equipment Design|Surface Properties 23 MIDN 16771872 Transpl. Int. 2006 10.1111/j.1432-2277.2006.00324.x 1 0 0 245 Humans|*Tissue and Organ Harvesting|Nephrectomy|Living Donors|*Kidney|Kidney Transplantation|Laparoscopy|Hospital Stay|Postoperative Complications|*Surgical Wound|Postoperative Period|Quality of Life|Europe 23 MIDN 16767454 Urologe A 2006 10.1007/s00120-006-1080-0 0 0 0 245 Humans|*Nephrectomy|*Retroperitoneal Space|*Tissue and Organ Harvesting|Living Donors|*Kidney|Kidney Transplantation|Laparoscopy|Length of Stay|*Surgical Wound|Quality of Life 23 MIDN 16570012 Transplantation 2006 10.1097/01.tp.0000203320.74256.fd 5 0 0 245 Humans|*Tissue and Organ Harvesting|*Laparoscopy|Nephrectomy|Living Donors|Kidney Transplantation|*Kidney|*Myotomy|Postoperative Complications 23 myo1f 17023661 Science 2006 10.1126/science.1131920 41 0 1 128 Mice|Animals|*Cell Adhesion|beta2 Integrin|N-Formylmethionine Leucyl-Phenylalanine|*Cell Motility|Neutrophils|Actin|Chemotaxis, Leukocyte|Listeria monocytogenes 25 ncln 17047369 Neurodegener Dis 2006 10.1159/000095268 3 0 0 65 Animals|*Amyloid Precursor Protein Secretases|signal peptide peptidase|Aspartic Acid Endopeptidases|Presenilin|Zebrafish Proteins|Zebrafish|Membrane Proteins|Proteolysis|Signal Transduction|Membrane Glycoproteins|*B Cells|Transforming Growth Factor beta 21 ncln 16908989 Neurodegener Dis 2006 10.1159/000080985 1 5 0 65 Humans|Animals|nicastrin protein|gamma-Secretase|Membrane Glycoproteins|APP protein, human|Amyloid beta-Protein Precursor|Aspartic Acid Endopeptidases|Membrane Proteins|Zebrafish|Zebrafish Proteins|Signal Transduction|Cell Membrane|Transforming Growth Factor beta 21 PALMD 16765103 Gene Expr. Patterns 2006 10.1016/j.modgep.2006.04.003 10 0 0 58 Pregnancy|Female|Mice|Animals|*Ciliary Body|*Retina|*Stem Cell|Paired Box Transcription Factors|Transcription Factor PAX6|Homeodomain Proteins|Eye Proteins|Repressor Proteins|*Neurons|Cell Differentiation|Lens, Crystalline|Gene Expression Regulation, Developmental|Cells, Cultured|Cellular Proliferation|Nerve Tissue Proteins|Organogenesis 20 PARP12 16885540 Reproduction 2006 10.1530/rep.1.00996 33 0 0 93 Pregnancy|Humans|Cattle|Animals|Female|Mice|*Transcriptome|*Endometrium|Embryo Implantation|cDNA Array|*Uterus|In Situ Hybridization|Gene Expression Profiling|mRNA|*Embryo, Mammalian|cDNA Libraries 20 PCDH11Y 17189292 Hum. Mol. Genet. 2006 PMC2590852 10.1093/hmg/ddl465 29 0 0 45 Humans|Male|*Chromosomes, Human, Y|*Amelogenin|Haplotype|Short Tandem Repeat|Sequence Tagged Site|Alleles|Chromosome Deletion|Asian Continental Ancestry Group|Polymorphism, Genetic|Polymerase Chain Reaction 24 PCDH11Y 16825765 Cytogenet. Genome Res. 2006 10.1159/000093329 6 0 1 45 Humans|Animals|*Gorilla gorilla|*Pan troglodytes|Pongo pygmaeus|Hominid|Primates|X-Inactivation|Chromosomes, Human, Y|Chromosomes, Human, X|Evolution, Molecular|In Situ Hybridization, Fluorescence 24 PCDH11Y 16741946 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2006 10.1002/ajmg.b.30339 7 0 0 45 Humans|*Klinefelter Syndrome|CpG Island|X-Inactivation|DNA Methylation|Alleles|Chromosomes, Human, X|DNA|Y Chromosome|Polymerase Chain Reaction 24 PDE3B signalling 16839743 Cell. Signal. 2006 10.1016/j.cellsig.2006.05.024 12 6 0 0 AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Protein Kinase A|*Phosphodiesterases|*Adipocytes|Phosphorylation|Signal Transduction|3',5'-Cyclic-AMP Phosphodiesterases|Cyclic AMP|Cyclic Nucleotide Phosphodiesterases, Type 3|Insulin|Lipogenesis|Enzyme Activation|Guanine Nucleotide Exchange Factors|erythromycin propionate-N-acetylcysteinate|*Erythromycin|*Acetylcysteine 21 PDE3B signalling 16808996 Neurosci. Lett. 2006 10.1016/j.neulet.2006.05.045 2 4 0 0 Animals|Rats|*Gated Channel, Cyclic-Nucleotide|Cyclic GMP|3',5'-Cyclic-AMP Phosphodiesterases|3',5'-Cyclic-GMP Phosphodiesterases|Cyclic Nucleotide Phosphodiesterases, Type 3|Cyclic AMP|Cyclic Nucleotide Phosphodiesterases, Type 5|Cerebral Arteries|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Ganglion, Trigeminal|Signal Transduction|Migraine|Artery, Mesenteric|mRNA|Headache 21 PDE3B signalling 16503395 Cell. Signal. 2006 10.1016/j.cellsig.2006.01.010 20 1 0 0 Rats|Mice|Animals|*Caveolae|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Adipocytes|*Plasma Membrane|CAV1 protein, human|Caveolin 1|Insulin|Lipolysis|3',5'-Cyclic-AMP Phosphodiesterases|Signal Transduction|Cyclic AMP|Lipogenesis|Membrane Microdomains|Protein Binding|Biological Transport|Cholesterol|Pde3b protein, mouse 21 pkd1l1 16741147 Arterioscler. Thromb. Vasc. Biol. 2006 10.1161/01.ATV.0000229694.97827.38 24 0 1 17 Humans|*Intracranial Hemorrhages|Brain Ischemia|Stroke|*Risk Factors|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Asian Continental Ancestry Group|Genotype|Logistic Models|*Ischemia 20 PPP1R3A 16907705 Ann. Hum. Genet. 2006 10.1111/j.1469-1809.2005.00248.x 8 0 0 909 Humans|Mason-Type Diabetes|*Diabetes Mellitus, Type 2|Frequencies, Allele|Splice Acceptor Site|Intron|Exons|Mutation|Base Sequence|Pedigree|Genetic Linkage|European Continental Ancestry Group|Promoter Regions, Genetic|*Chromosome|PPP1R3B protein, human|Protein Phosphatase 1 40 PPP1R3A 16598745 J. Cell. Biochem. 2006 10.1002/jcb.20857 0 0 0 909 Humans|Rippling muscle disease, 1|*Autoantigens|TTN protein, human|Titin|*Muscular Diseases|*Muscle, Skeletal|Muscle Contraction|Muscle Proteins|Myasthenia Gravis|Protein Isoforms|Amino Acid Sequence 40 PYHIN1 16479015 Mol. Cell. Biol. 2006 PMC1430239 10.1128/MCB.26.5.1979-1996.2006 17 8 0 57 Humans|TP53 protein, human|Tumor Suppressor Protein p53|Proto-Oncogene Proteins c-mdm2|Nuclear Protein|Ubiquitination|Proto-Oncogene Proteins|Cell Nucleus|TYRP1 protein, human|*Membrane Glycoproteins|Ubiquitin|Gene Expression Regulation, Neoplastic|Protein Isoforms|Tumor Cells, Cultured|Downregulation|Interferon 20 RAX2 17085965 Mol. Cells 2006 1 0 0 14 *Schizosaccharomyces|Schizosaccharomyces pombe Proteins|Microtubule|Actin|Microtubule-Associated Proteins|Cytoskeleton|Cell Polarity|Cell Cycle|Cell Cycle Proteins|Formins|*Biological Phenomena|Models, Biological|Tea1 protein, S pombe 25 Resp18 17168313 Sheng Wu Gong Cheng Xue Bao 2006 0 0 0 423 Mice|Animals|*Gene Targeting|Bacteriophage lambda|Chromosomes, Artificial, Bacterial|Recombination, Genetic|Genetic Engineering|Genetic Vectors|Escherichia coli|PCR|Knockout Mouse 23 SCAMP2 16870614 J. Biol. Chem. 2006 10.1074/jbc.M602848200 23 2 0 316 Animals|Rats|Humans|*Serotonin Plasma Membrane Transport Proteins|flotillins|Membrane Proteins|Cell Membrane|Biological Transport|Protein Binding|Membrane Glycoproteins|Nerve Tissue Proteins|Protein Structure, Tertiary|Membrane Fusion|Serotonin|Membrane Microdomains|Syntaxin-1A Protein|Cytoplasm|Transfection|Brain|Co-Immunoprecipitation 26 SCGB1D2 17163411 Int. J. Cancer 2006 10.1002/ijc.22471 0 0 1 18 SCGB2A2 protein, human|Mammaglobin A|SCGB1D2 protein, human|*Secretoglobins|Fibroadenomas|Uteroglobin|*Upregulation|Neoplasm Proteins|Receptors, Estrogen|Biomarkers, Tumor|Proteolipids|Gene Expression Regulation, Neoplastic|mRNA|*Transcriptional Activation|Myelin Proteins 156 SCGB1D2 17158753 Endocr. Relat. Cancer 2006 10.1677/ERC-06-0001 82 0 5 18 Prognosis|Neoplastic Cells, Circulating|Lymphatic Metastasis|Bone Marrow|Biomarkers, Tumor|Lymph Nodes|Cancer Stem Cells|ERBB2 protein, human|Receptor, ErbB-2 156 SCGB1D2 16916643 Mol. Cell 2006 PMC1626587 10.1016/j.molcel.2006.07.015 60 25 0 18 Animals|AURKB protein, human|*Aurora Kinase B|Kinetochores|Spindle Apparatus|Mitosis|Cell Cycle Proteins|Signal Transduction|Phosphorylation|Anaphase|Centrosomes|Proto-Oncogene Proteins c-raf|Mitogen-Activated Protein Kinases|MAP2K1 protein, human|MAP Kinase Kinase 1|*Cell Cycle Checkpoints|Cell Cycle 156 SCGB1D2 16603086 BMC Cancer 2006 PMC1513245 10.1186/1471-2407-6-88 15 1 1 18 Humans|Female|SCGB2A2 protein, human|*Mammaglobin A|SCGB1D2 protein, human|*Secretoglobins|Mammaglobin B|Uteroglobin|Neoplasm Proteins|Proteolipids|Carrier Proteins|Biomarkers, Tumor|Myelin Proteins|*Genital Neoplasms, Female|RNA, Messenger 156 SCRN1 16630140 Cancer Sci. 2006 10.1111/j.1349-7006.2006.00194.x 11 0 1 65 Humans|Male|Adult|Female|*Stomach Neoplasms|*Oligonucleotide Array Sequence Analysis|*Immunotherapy|T-Lymphocytes, Cytotoxic|Antigens, Neoplasm|Cancer Vaccines|HLA-A24 Antigen|HLA-A Antigens|Epitopes, T-Lymphocyte|Blotting, Northern|*Immunologic Factors|Gene Expression Profiling|Cell Line, Tumor|RNA, Messenger|SCRN1 protein, human|Nerve Tissue Proteins 21 SEZ6L 17086543 J. Neurosci. Res. 2006 10.1002/jnr.21103 15 0 3 15 Humans|Child|*Seizures, Febrile|Epilepsy, Generalized|*Brain|*Seizure|*Mutation|DNA Mutational Analysis|Epilepsy|Heterozygote|Pedigree|Exons|Genotype|Genetic Predisposition to Disease|Receptors, GABA-A 21 SPANXA1 17036333 Int. J. Cancer 2006 10.1002/ijc.22259 6 0 0 37 Male|*Methyl-CpG-Binding Protein 2|*Multiple Myeloma|*Promoter Regions, Genetic|CpG Islands|cytidylyl-3'-5'-guanosine|*Dinucleoside Phosphates|DNA Methylation|5 Azacytidine|Transcription Factors|Gene Expression Regulation, Neoplastic|Protein Binding|Reporter Gene|Cell Line, Tumor|Transcriptional Activation|Chromatin Immunoprecipitation 27 SPANXA1 17012309 Mol. Hum. Reprod. 2006 10.1093/molehr/gal079 10 0 2 37 Humans|Male|Mice|Rats|Animals|*Spermatids|*Nuclear Envelope|Spermiogenesis|Acrosome|Spermatozoa|Testis|*Hominidae|Amino Acid Sequence|Nuclear Proteins|Genes, Regulator|X Chromosome|Meiosis|Sequence Alignment|Cell Nucleus|*Morphogenesis|Open Reading Frames|Cytoplasm|SPANXD protein, human 27 SPANXA1 16390498 Int. J. Androl. 2006 10.1111/j.1365-2605.2005.00615.x 3 0 0 37 Humans|Male|Testicular Germ Cell Tumor|*Testis|*Testicular Neoplasms|*Neoplasms, Germ Cell and Embryonal|Seminomas|Embryonal Carcinomas|Spermatogonia|Spermatocytes|Gene Expression Regulation, Neoplastic|*Inferior Colliculi|Carcinoma in Situ 27 STOML1 17090228 Biochem. J. 2006 PMC1798439 10.1042/BJ20060950 35 1 0 71 Humans|Mice|Animals|*Neutrophils|Rab27a Protein|*Granulocytes|*Cytoplasmic Granules|Sytl1 protein, mouse|Membrane Proteins|rab GTP-Binding Proteins|Exocytosis|Secretory Vesicles|*Leukocyte Count|Phagosome|Phagocytosis|*Biological Transport|HL-60 Cells|RAB27A protein, human|JFC1 protein, human|Rab27a protein, mouse 20 STOML1 16501878 J. Mol. Evol. 2006 10.1007/s00239-005-0086-3 11 0 1 71 Humans|Animals|sterol carrier proteins|*Carrier Proteins|Amino Acid Sequence|Sequence Alignment|Sequence Homology, Amino Acid|Sterols|Phylogeny|Phosphatidylcholines|Enoyl-CoA Hydratase|Fungi|Eukaryotic Cells|HSDL2 protein, human|Hydroxysteroid Dehydrogenases 20 TARBP1 17151120 J. Virol. 2006 PMC1797547 10.1128/JVI.02014-06 2 1 0 41 Humans|*Dependovirus|Viral Proteins|Binding Site|Base Sequence|DNA-Binding Proteins|Virus Integration|DNA 26 TCF15 16478789 J. Cell. Sci. 2006 10.1242/jcs.02792 33 5 1 58 Mice|Animals|AKT1 protein, human|*Protein Kinase B|Adipogenesis|*Cell Differentiation|Adipocytes|3T3-L1 Cells|Fibroblasts|Signal Transduction|Cells, Cultured|Knockout Mouse|Downregulation|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one|Chromones|Upregulation|Gene Expression|Morpholines 39 TCF15 16387292 Dev. Biol. 2006 10.1016/j.ydbio.2005.11.027 24 0 1 58 Mice|Animals|*Somites|Myogenin|myogenic factor 6|Myogenic Regulatory Factors|Myogenic Regulatory Factor 5|MyoD Protein|PAX3 Transcription Factor|Paired Box Transcription Factors|Trans-Activators|Muscle Development|Muscle Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Muscle, Skeletal|Embryonic Development|Mesoderm 39 TMEFF1 16407223 J. Biol. Chem. 2006 10.1074/jbc.M510687200 5 4 1 69 Humans|TYRP1 protein, human|*Membrane Glycoproteins|Serine Endopeptidases|Protein Structure, Tertiary|SPINT1 protein, human|Proteinase Inhibitory Proteins, Secretory|LDLR protein, human|Low Density Lipoprotein Receptor|Amino Acid Sequence|Protein Binding|Cell Line|Transfection|Membrane Proteins|Cloning, Molecular|Mutation|Sequence Homology, Amino Acid|ST14 protein, human 26 ZNF185 16799630 Oncogene 2006 10.1038/sj.onc.1209769 21 4 0 64 Humans|Male|*Actins|*Microfilament Proteins|Actin Cytoskeleton|PDLIM4 protein, human|LIM Domain Proteins|Cytoskeleton|Amino Acid Sequence|*Prostate Cancer|DNA-Binding Proteins|Focal Adhesions|Protein Binding|Tumor Suppressor Proteins|cDNA|ZNF185 protein, human|Cytoskeletal Proteins 24 ZNF91 16606703 Genome Res. 2006 PMC1457049 10.1101/gr.4843906 44 0 5 55 Humans|Animals|Phylogeny|*Zinc Finger|*Primate|Transcription Factors|Evolution, Molecular|Multigene Family|Gene Duplication|Genome, Human|Repressor Proteins|Kruppel-Like Transcription Factors|Mammals|Gene Expression Profiling 26 ACTBP2 16135442 Yi Chuan 2005 0 0 0 0 Humans|China|*Genetic Polymorphism|Gene Frequencies|Genetics, Population|Microsatellite Repeats|Paternity|Alleles|Genetic Markers|Genotype|Asian Continental Ancestry Group|Heterozygote|PCR|DNA|Electrophoresis 67 ACTBP2 16100762 Croat. Med. J. 2005 0 0 0 0 Typing, DNA|Short Tandem Repeat|RFLP|DNA|Polymerase Chain Reaction|Chromosome Mapping 67 ACTBP2 15939167 Forensic Sci. Int. 2005 10.1016/j.forsciint.2005.02.003 0 0 0 0 Humans|*Frequencies, Allele|Genetics, Population|DNA Fingerprinting|Microsatellite Repeats|Polymerase Chain Reaction|European Continental Ancestry Group|Research Design 67 ACTBP2 15939159 Forensic Sci. Int. 2005 10.1016/j.forsciint.2005.02.018 1 0 0 0 Humans|*DNA Fingerprinting|DNA Primers|Tandem Repeat Sequences|DNA|Polymerase Chain Reaction|*Crimes|*Genomics|*Intelligence 67 ACTBP2 15639615 Forensic Sci. Int. 2005 10.1016/j.forsciint.2004.05.006 0 0 0 0 Humans|*Chromosomes, Human, Pair 6|Gene Frequency|Genetics, Population|DNA Fingerprinting|Tandem Repeat Sequences|Polymorphism, Genetic|European Continental Ancestry Group|Pseudogenes|Polymerase Chain Reaction|*Chromosome Structures|Austria|Humans|*Chromosomes, Human, Pair 6|Gene Frequency|Genetics, Population|DNA Fingerprinting|Tandem Repeat Sequences|Polymorphism, Genetic|European Continental Ancestry Group|Pseudogenes|Polymerase Chain Reaction|*Chromosome Structures|Austria 67 ADAM7 15883027 Biochem. Biophys. Res. Commun. 2005 10.1016/j.bbrc.2005.04.067 11 0 1 20 Male|Mice|Animals|*Epididymis|ADAM Proteins|Sperm|Sperm Head|Acrosome Reaction|Testis|Membrane Proteins|Amino Acid Sequence|Gene Expression|Adam7 protein, mouse|Adam28 protein, mouse 24 AGAP1 16332543 Curr. Biol. 2005 10.1016/j.cub.2005.10.065 13 0 1 202 *ADP-Ribosylation Factor 1|ADP-Ribosylation Factors|GTPase-Activating Proteins|Protein Binding|Adaptor Proteins, Signal Transducing|PXN protein, human|Paxillin|Golgi Apparatus|Guanosine Triphosphate|Mutation|*DNA Mutational Analysis|Mutagenesis|Hydrolysis|Protein Transport|Actin 25 AGAP1 16079295 J. Cell. Sci. 2005 10.1242/jcs.02486 31 5 2 202 *GTPase-Activating Proteins|*Transcription Factor AP-1|ADP-ribosylation factor related proteins|*ADP-Ribosylation Factors|ADP-Ribosylation Factor 1|*Golgi Apparatus|Endosomes|Protein Transport|Guanine Nucleotide Exchange Factors|Membrane Proteins|CD71 antigen|Transferrin Receptor|*Clathrin-Coated Vesicles|Adaptor Proteins, Signal Transducing|Adaptor Protein Complex 3|Cell Line|Antigens, CD 25 AGAP1 15892143 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2005 10.1002/ajmg.b.30180 18 0 1 202 Humans|*Autistic Disorder|In Situ Hybridization, Fluorescence|Genetic Linkage|*Chromosome 2|*Chromosome 3|Genotype|Linkage Disequilibrium|Chromosome Mapping|Lod Score|Genetic Predisposition to Disease|Polymorphism, Genetic|*Chromosome Structures|Exons|Microsatellite Repeats|Family Health|Family|Sibling 25 CPA6 15950771 Brain Res. Mol. Brain Res. 2005 10.1016/j.molbrainres.2005.02.026 9 0 1 44 Humans|Male|Animals|Mice|Rats|Cpa6 protein, mouse|*Carboxypeptidases A|In Situ Hybridization|mRNA|Brain|Gene Expression|Embryo, Mammalian|Olfactory Bulb|Hippocampus|Cerebral Cortex|Hypothalamus 24 CRYZ 16303216 Vaccine 2005 10.1016/j.vaccine.2005.10.023 4 0 0 488 Infant|Humans|*Diphtheria-Tetanus-Pertussis Vaccine|*Haemophilus influenzae type b|Indonesia|Double-Blind Method|Haemophilus influenzae type b polysaccharide vaccine|*Haemophilus Vaccines|*Bacterial Capsules|*Diphtheria-Tetanus Vaccine|Vaccines, Combined|Vaccines, Conjugate|polyribose phosphate|Polysaccharides, Bacterial|Immunization, Secondary|Haemophilus Infections|Tetanus|*Toxoids|Immunization Schedule|Vaccination 164 CST8 16034113 J. Immunol. 2005 10.4049/jimmunol.175.3.1724 6 1 0 190 Humans|Mice|Animals|*Chickens|*Gene Cluster|Amino Acid Sequence|Base Sequence|cDNA|Cloning, Molecular|Complement Activation|Exon|Transcription Factors|Cell Lines|Complement|RNA, Messenger|Creg protein, mouse|Repressor Proteins 31 CST8 15713831 J. Androl. 2005 10.1002/j.1939-4640.2005.tb01092.x 1 0 0 190 Male|Female|Mice|Animals|*Epididymis|*Mice, Transgenic|*Spermatogenesis|Testis|*Cystatins|*Pituitary Diseases|*Gland, Pituitary|*Promoter Regions, Genetic|Spermatids|Messenger RNA|Spermatozoa|Pituitary Gland, Anterior|In Situ Hybridization|Amino Acid Sequence 31 DAZ3 15744033 J. Med. Genet. 2005 PMC1736009 10.1136/jmg.2004.025833 38 0 4 1 20 DDX10 15951287 Haematologica 2005 4 0 0 68 Humans|Child|nuclear pore complex protein 98|*In Situ Hybridization, Fluorescence|Nucleoporin|Leukemia, Myeloid|Translocation, Genetic|*Malignancies, Hematopoietic|Oncogene Proteins, Fusion|Base Sequence|Amino Acid Sequence|Homeodomain Proteins 29 DGCR6 15821931 Hum. Genet. 2005 10.1007/s00439-005-1267-2 3 1 0 67 Humans|Animals|Leukocytes, Mononuclear|Amino Acid Sequence|DiGeorge Syndrome|Base Sequence|Gene Expression|EBV|B Cells|NF-kappa B|Extracellular Matrix Proteins|mRNA|Promoter Regions, Genetic|DGCR6 protein, human 24 ETV3 15804237 Biochem. J. 2005 PMC1180720 10.1042/BJ20050214 15 2 0 1655 Mice|Animals|*Matrilin Proteins|SOX9 protein, human|*SOX9 Transcription Factor|*Binding Sites|*Promoter Regions, Genetic|Chondrocytes|Chondrogenesis|Cartilage|Enhancer Elements, Genetic|SOXD Transcription Factors|Conserved Sequence|Reporter Gene|Nuclear Proteins|Base Sequence|Growth Plate|Introns|Mice, Transgenic|Extracellular Matrix Proteins 23 EVX2 16322559 Genes Dev. 2005 PMC1315393 10.1101/gad.351105 21 0 2 14 Mice|Animals|Genes, Homeobox|Homeodomain Proteins|Transcription Factors|Gene Cluster|Gene Expression Regulation, Developmental|Neoplasm Proteins|Phenotype|Hindlimb 33 FILIP1 15794127 Anat Sci Int 2005 10.1111/j.1447-073x.2005.00101.x 12 0 0 40 Chlorocebus aethiops|Animals|FLNA protein, human|*Filamins|*Cell Shape|F-Actin|*Neurons|Cytoskeletal Proteins|Cell Migration|Carrier Proteins|Actin Cytoskeleton|COS-7 Cells|Cerebral Cortex|Protein Binding|*Biophysical Phenomena 22 GBX1 16193514 Dev. Dyn. 2005 10.1002/dvdy.20568 16 0 0 17 Pregnancy|Female|Animals|Mice|*Transcription Factor|*Interneurons|LIM-Homeodomain Proteins|Homeodomain Proteins|Spinal Cord|Neurons|PAX2 Transcription Factor|Posterior Horn Cells|Gene Expression Regulation, Developmental|gamma-Aminobutyric Acid|Cell Differentiation|bHLH Transcription Factors|In Situ Hybridization|*Parturition 34 GBX1 15703279 Development 2005 10.1242/dev.01685 26 0 0 17 Animals|*Neural Plate|*Hindbrain|*Mesencephalon|Zebrafish Proteins|Zebrafish|Otx Transcription Factors|Organizers, Embryonic|*Signal Transduction|Body Patterning|Gastrula|Transcription Factors|Gene Expression Regulation, Developmental|Wnt Proteins|Trans-Activators|Nerve Tissue Proteins 34 glycosis 16383033 Zhonghua Shao Shang Za Zhi 2005 0 1 0 0 Animals|Rats|*Glycolysis|*Myocytes, Cardiac|*Hypoxia|Rats, Sprague-Dawley|Cell Hypoxia|Hypoxia-Ischemia, Brain|Cells, Cultured 21 GMFB 16115230 Histopathology 2005 10.1111/j.1365-2559.2005.02224.x 2 2 0 125 *Thymoma|*Glia Maturation Factor|*Thymus Neoplasms|*Cell Differentiation|*Lymphocyte Activation|*Hematopoiesis 26 GMFB 15661366 Brain Res. Mol. Brain Res. 2005 10.1016/j.molbrainres.2004.09.027 3 0 0 125 Animals|*Glia Maturation Factor|*Brain Injury|Glial Fibrillary Acidic Protein|Astrocytes|mRNA|Neurons|In Situ Hybridization|Glia|Brain|Immunohistochemistry|Western Blotting 26 GPR85 15893849 Brain Res. Mol. Brain Res. 2005 10.1016/j.molbrainres.2005.04.002 10 0 0 29 Animals|Rats|Humans|*Monkey|*Prosencephalon|In Situ Hybridization|G-Protein-Coupled Receptors|Neurons|mRNA|Nerve Tissue Proteins|Gene Expression|Ligands|Hippocampal Formation 25 GRIN3B 15722182 Neurosci. Lett. 2005 10.1016/j.neulet.2004.11.064 9 0 1 31 Animals|Humans|Mice|NR3B NMDA receptor|*Receptors, N-Methyl-D-Aspartate|*Hippocampus|In Situ Hybridization|Protein Subunits|Prosencephalon|mRNA|Exons|Cloning, Molecular 21 HMG20B 16227968 Nat. Cell Biol. 2005 10.1038/ncb1312 31 4 2 74 22 IMPG1 16354621 Curr. Eye Res. 2005 10.1080/02713680500351039 2 0 0 26 *Retinitis Pigmentosa|Genes, Recessive|Pedigree|Eye Proteins|Genetic Linkage|Exons|Mutation|Sequence Analysis, DNA|Polymorphism, Single Nucleotide 29 IMPG1 16185951 Exp. Eye Res. 2005 10.1016/j.exer.2005.02.011 1 0 0 26 Humans|Animals|Bees|*Retinal Drusen|*Macaca mulatta|Macular Degeneration|Gene Frequency|Genotype|Phenotype|Genetic Predisposition to Disease|Alleles|Genetic Markers|Chromosomes, Human|Caribbean 29 KLF16 16172401 Proc. Natl. Acad. Sci. U.S.A. 2005 PMC1216828 10.1073/pnas.0500630102 9 4 0 93 Humans|*TGFbeta|*Keratinocytes|*Calcium|SMAD3 protein, human|Smad3 Protein|Cyclin-Dependent Kinase Inhibitor p21|TGFB1 protein, human|TGF-beta1|Sp1 Transcription Factor|Cyclins|Signal Transduction|Cell Division|Epidermis|Cell Nucleus|Cell Cycle 26 LSG1 16260602 Mol. Cell. Biol. 2005 PMC1280274 10.1128/MCB.25.22.9859-9873.2005 24 0 1 94 Ribosomes|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Ribosome Subunits, Large, Eukaryotic|Pre-rRNA|ATPase|Ribosomal Proteins|18S RRNA|Cell Nucleus|Export, Nuclear|RNA Processing, Post-Transcriptional|Adenosine Triphosphate|ARB1 protein, S cerevisiae|ATP-Binding Cassette Transporters 26 LSG1 16209721 BMC Biol. 2005 PMC1262696 10.1186/1741-7007-3-21 25 0 3 94 Humans|*GTPases|Genome|Evolution, Molecular|Guanosine Triphosphate|Genomic, Comparative|Phylogeny|Eukaryotic Cells 26 MIDN 16180026 World J Urol 2005 10.1007/s00345-005-0008-4 2 0 0 245 Humans|*Living Donors|*Quality of Life|*Tissue and Organ Harvesting|Nephrectomy|*Kidney|Kidney Transplantation|Laparoscopy|Hospital Stay|*Abdomen|*Surgical Wound|Postoperative Period|Survey 23 MTX3 16147884 DNA Seq. 2005 10.1080/10425170500129660 0 0 0 133 Animals|*Xenopus laevis|*Amino Acid Sequence|*DNA, Complementary|Phylogeny|Xenopus Proteins|Sequence Alignment|Base Sequence|Sequence Homology, Amino Acid|Zebrafish|Cloning, Molecular|Sequence Analysis, DNA|Gene Expression Regulation, Developmental|Protein Domains 21 MTX3 15970328 Plasmid 2005 10.1016/j.plasmid.2005.04.003 5 0 0 133 *Bacillus thuringiensis|Bacillus mycoides|*Plasmid|Hemolysin Proteins|Endotoxins|Base Sequence|Amino Acid Sequence|DNA, Bacterial|*Insecticides|Cloning, Molecular|DNA Replication|Bacterial Proteins|ORFs|Bacillus 21 PALMD 16323283 Eur. J. Cell Biol. 2005 10.1016/j.ejcb.2005.07.002 8 1 0 58 Animals|Rats|Chlorocebus aethiops|Palmd protein, mouse|*Cytosol|*Membrane Proteins|PALM protein, human|*Phosphoproteins|*Protein Isoforms|Cell Membrane|Amino Acid Sequence|Cell Nucleus|Phosphorylation|COS Cells|Cytoplasm|*Membrane|Sequence Homology, Amino Acid|Membrane Microdomains|Cytoskeleton|DNA, Complementary 20 PALMD 15969763 BMC Ophthalmol 2005 PMC1183217 10.1186/1471-2415-5-14 4 1 0 58 Mice|Animals|*Retina|PALM protein, human|*Membrane Proteins|*Phosphoproteins|Lens, Crystalline|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Cell Differentiation|RNA, Messenger|Animals, Newborn 20 PDE3B signalling 16219000 J. Neuroendocrinol. 2005 10.1111/j.1365-2826.2005.01362.x 22 1 0 0 *Leptin|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Phosphatidylinositol|Phosphatidylinositol 3-Kinases|*Hypothalamus|*Signal Transduction|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|Phosphorylation|Cyclic AMP|Insulin|Phosphatidylinositol 3-Kinase|Insulin Receptor Substrate 1|Obesity|Body Weight|Eating|Homeostasis 21 PDE3B signalling 15961276 Cell. Signal. 2005 10.1016/j.cellsig.2005.05.007 22 5 0 0 Animals|Rats|*Insulin|*Lipogenesis|*Adipocytes|*Glucose Transporter Type 4|*Insulin, Regular, Human|Cyclic Nucleotide Phosphodiesterases, Type 3|Lipolysis|AKT1 protein, human|Protein Kinase B|Cyclic AMP|Cyclic AMP-Dependent Protein Kinases|Signal Transduction|Isoproterenol|Cyclic Nucleotide Phosphodiesterases, Type 4|Phosphorylation|beta-Adrenergic Agonist|*Biological Transport|Guanine Nucleotide Exchange Factors 21 PPP1R3A 15870946 Oncol. Rep. 2005 1 1 0 909 *Protein Phosphatase 1|*Colorectal Cancer|Liver Neoplasms|Point Mutation|Mutations|Exons|*Neoplastic Processes|Polymorphism, Single-Stranded Conformational|*Colonic Neoplasms 40 PTPRCAP 16086313 Hum. Mutat. 2005 10.1002/humu.20207 30 0 0 34 Humans|*Promoter Regions, Genetic|Haplotypes|Gene Expression Regulation|Frequencies, Allele|Transcription Start Site|Transcription, Genetic|Reporter Gene|Alleles|Polymorphism, Single Nucleotide|Binding Sites|Transcription Factors|Protein Binding|GABRP protein, human|Receptors, GABA-A|ORM2 protein, human|Orosomucoid 48 PTPRCAP 15985726 Indian J Med Sci 2005 10.4103/0019-5359.16254 1 0 0 34 *B-Lymphocytes|Immunophenotyping|Leukemia, Lymphocytic, Chronic, B-Cell|PTPRC protein, human|*Leukocyte Common Antigens|Leukemia, B-Cell|CD5 Antigens|Leukemia, Hairy Cell|Lymphoproliferative Disorders|Lymphoma, B-Cell|Antigens, CD|Flow Cytometry 48 Resp18 15655120 Hypertension 2005 10.1161/01.HYP.0000154678.64340.7f 13 0 0 423 Rats|Animals|*Quantitative Trait Loci|*Blood Pressure|*Rats, Inbred Dahl|Animals, Congenic|Chromosome Mapping|*Kidney|*Blood Pressure Determination|Sodium Chloride, Dietary|Gene Chips|Expressed Sequence Tags|regulated endocrine secretory protein 18|Nerve Tissue Proteins|Gene Expression 23 SCAMP2 16030257 Mol. Biol. Cell 2005 PMC1237056 10.1091/mbc.e05-03-0231 22 4 0 316 Rats|Animals|phospholipase D1|*PC12 Cells|*Exocytosis|*Phospholipase D|ADP-ribosylation factor 6|*ADP-Ribosylation Factors|Secretory Vesicle|Plasma Membranes|Membrane Fusion|Chromaffin Cells|Membrane Proteins|Carrier Proteins|Guanine Nucleotide Exchange Factors|Protein Binding|Calcium|Transfection|Peptides 26 SCAMP2 15840657 J. Cell. Sci. 2005 10.1242/jcs.02315 0 4 5 316 Animals|Humans|*Membrane Transport Proteins|*Sodium-Hydrogen Exchangers|*Protein Transport|Golgi Apparatus|trans Golgi Network|Protein Binding|Carrier Proteins|Membrane Proteins|Protein Structure, Tertiary|Cell Membrane|Amino Acid Sequence|Two-Hybrid System Techniques|Co-Immunoprecipitation|*Biological Transport|Transfections|Cytosol|SCAMP5 protein, human 26 SCGB1D2 16319979 Breast Cancer Res. Treat. 2005 10.1007/s10549-005-9085-8 11 0 2 18 Mammaglobin A|KRT19 protein, human|Cytokeratin-19|Sentinel Lymph Node Biopsy|Lymphatic Metastasis|RNA, Neoplasm|Uteroglobin|Biomarkers, Tumor|Neoplasm Proteins|Lymph Nodes|RNA, Messenger 156 SCGB1D2 15668787 Acta Neuropathol. 2005 10.1007/s00401-004-0972-6 4 0 0 18 Humans|*Pituitary Neoplasms|*Down-Regulation|SCGB1D2 protein, human|*Secretoglobins|*Adenoma|*Pituitary Gland|*Pituitary Diseases|Mammaglobin B|mRNA|Immunohistochemistry|Uteroglobin|Proteolipids 156 SCRN1 16367923 Cancer Sci. 2005 10.1111/j.1349-7006.2006.00136.x 75 1 2 65 *Decitabine|*Stomach Neoplasms|*Oligonucleotide Array Sequence Analysis|Early Detection of Cancer|CpG Islands|Azacitidine|Genes, Tumor Suppressor|DNA Methylation|Promoter Regions, Genetic|Upregulation|Gene Expression Regulation, Neoplastic|Gene Silencing|PLAGL1 protein, human|Tumor Suppressor Proteins|Cell Line, Tumor|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|Hydroxamic Acids 21 TBPL1 15767669 Mol. Cell. Biol. 2005 PMC1061635 10.1128/MCB.25.7.2632-2643.2005 16 5 0 1191 Humans|Mice|Animals|*TATA-Box Binding Protein|*Genes, fos|*Neurofibromatosis 1|TFIIA|TATA Box Binding Protein-Like Proteins|TATA Box|Promoter Regions, Genetic|Genes, Neurofibromatosis 1|Transcription, Genetic|Transcriptional Activation|Proto-Oncogene Proteins c-fos 28 TCF15 16100089 Development 2005 10.1242/dev.01961 22 0 2 58 *Somites|CTNNB1 protein, human|*beta Catenin|WNT6 protein, human|Wnt Proteins|Wnt1 Protein|Transcription Factor|Mesoderm|*Wnt Signaling Pathway|Ectoderm|Trans-Activators|Zebrafish Proteins|Gene Expression Regulation, Developmental|Proto-Oncogene Proteins|Basic Helix-Loop-Helix Transcription Factors 39 TMEFF1 16167981 Anim. Genet. 2005 10.1111/j.1365-2052.2005.01334.x 7 0 0 69 Humans|Horses|Animals|Male|Female|Mice|*Color|*Mapping, Linkage|Genetic Linkage|Microsatellite Repeats|Pedigree|Single Nucleotide Polymorphisms|Chromosome|DNA Primers|Phenotype 26 ZNF185 15731117 Hum. Mol. Genet. 2005 10.1093/hmg/ddi091 15 0 2 64 SMARCA4 protein, human|*DNA Helicases|*Nuclear Proteins|*Transcription Factors|*Lung Cancer|Promoter Regions, Genetic|Chromatin Immunoprecipitation|Chromosomal Proteins, Non-Histone|Activation, Transcriptional|Gene Expression Regulation|DNA Methylation|Oligonucleotide Array Sequence Analysis|Chromatin Assembly and Disassembly|Histone|Cell Line, Tumor|RNA, Messenger|Chromatin 24 ZNF185 15709204 Clin. Cancer Res. 2005 9 0 0 64 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Interferon-alpha|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Hepacivirus|Hepatitis B virus|Cell Line, Tumor|*Gene Expression|Hepatitis C 24 ABTB1 15379262 Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2004 0 2 0 20 *BTB-POZ Domain|*Heat Shock|Transcription Factors|Homeodomain Proteins|Drosophila Proteins|Promoter Regions, Genetic|HSP90 Heat-Shock Proteins 31 ACTBP2 15600185 Sichuan Da Xue Xue Bao Yi Xue Ban 2004 0 0 0 0 Humans|*Polymorphism, Genetic|*Asian Continental Ancestry Group|Gene Frequency|Genetics, Population|Alleles|Tandem Repeat Sequences|Genotype|Forensic Medicine|Laxatives 67 ACTBP2 15490457 Electrophoresis 2004 10.1002/elps.200406069 9 0 2 0 Humans|Child|*Haplotypes|*Germ-Line Mutation|*Tandem Repeats, Short|Paternity|DNA Fingerprinting|Allele|Mutations|Polymerase Chain Reaction|Sequence Analysis, DNA 67 ACTBP2 15322828 Int. J. Legal Med. 2004 10.1007/s00414-004-0473-0 3 0 0 0 *Alleles|DNA Fingerprinting|DNA Primers|Tandem Repeat Sequences|*Mutations|Genotype|Polymerase Chain Reaction 67 ACTBP2 15235792 Int. J. Legal Med. 2004 10.1007/s00414-004-0459-y 0 0 0 0 Humans|Animals|*PCR|DNA Fingerprinting|Short Tandem Repeat|Gene Frequency|Polymorphism, Genetic|Specificity|DNA|European Continental Ancestry Group|Heterozygote 67 ADAM7 15504110 Biochem. J. 2004 PMC1134937 10.1042/BJ20041444 15 2 1 20 Humans|Animals|*Integrin alpha4beta1|*Disintegrins|integrin alpha4beta7|Cell Adhesion|ADAM Proteins|Jurkat Cell|Amino Acid Sequence|Binding Sites|Tumor Cells, Cultured|Protein Binding|*Protein Domains|ADAM28 protein, human|ADAM33 protein, human 24 ADAM7 14963094 Mol. Biol. Evol. 2004 10.1093/molbev/msh080 10 0 1 20 Male|Phylogeny|Disintegrins|ADAM Proteins|Amino Acid Sequence|Membrane Glycoproteins|Spermatogenesis|Evolution, Molecular|Fertilins|Membrane Proteins|Testis|Binding Sites|Sperm|*Reproduction|Codon 24 AGAP1 15381706 J. Biol. Chem. 2004 10.1074/jbc.M410565200 9 3 0 202 Humans|Animals|Rats|Mice|*Soluble Guanylyl Cyclase|Guanylate Cyclase|Cyclic GMP|Receptors, Cytoplasmic and Nuclear|Nitric Oxide|Phosphorylation|Signal Transduction|Blotting, Western|mRNA|AGAP1 protein, human|GTPase-Activating Proteins|AGAP1 protein, mouse 25 ATL2 15238540 Genetics 2004 PMC1470891 10.1534/genetics.104.028043 28 0 0 95 *Arabidopsis|*Zinc|Arabidopsis Proteins|*RING Finger Domains|jasmonic acid|Oxylipins|Cyclopentanes|Salicylic Acid|Gene Expression Regulation, Plant|Ethylenes|E3 Ubiquitin Ligase|Zinc Fingers|Multigene Family|Sequence Homology, Amino Acid|DNA-Binding Proteins|Plant Diseases|Signal Transduction|Phenotype 23 CLIC6 14761608 Zhonghua Xue Ye Xue Za Zhi 2004 0 2 0 37 Humans|*Homoharringtonine|*HL-60 Cells|*Proteomics|*Apoptosis|Harringtonines|Electrophoresis, Gel, Two-Dimensional|Antineoplastic Agents, Phytogenic|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization 21 DAZ3 15520406 J. Med. Genet. 2004 PMC1735624 10.1136/jmg.2004.022111 40 0 3 1 20 DGCR6 15333760 Pediatr. Res. 2004 10.1203/01.PDR.0000136151.50127.1C 13 0 1 67 Humans|Animals|*Chickens|*Genes, Modifier|Amino Acid Sequence|Transcription Factors|DiGeorge Syndrome|Base Sequence|Nuclear Proteins|Chromosome Mapping|Sequence Homology, Amino Acid|Cloning, Molecular|Neural Crest Cell|Embryo, Mammalian|DNA, Complementary|Gene Expression|Pharyngeal Arches|DGCR6 protein, human|Extracellular Matrix Proteins|UFD1L protein, human 24 DGCR6 15274030 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2004 10.1002/ajmg.b.30049 22 0 1 67 Adult|Humans|*Schizophrenia|Haplotypes|Proline Dehydrogenase|SNPs|Genotype|*Chinese|Genetic Predisposition to Disease|Alleles|Linkage Disequilibrium|Gene Frequency|Psychosis|China|PRODH protein, human 24 DNAJC14 14993367 Mol. Interv. 2004 4 1 0 65 *G-Protein-Coupled Receptors|Ligands|Cell Membrane|Protein Transport|TYRP1 protein, human|*Membrane Glycoproteins|Protein Binding|Endoplasmic Reticulum|Signal Transduction|Proteins, Membrane-Associated 20 ETV3 14754893 J. Biol. Chem. 2004 10.1074/jbc.M311991200 18 10 0 1655 Transcriptional Activation|Promoter Regions, Genetic|Repressor Proteins|*Activating Transcription Factor 2|Transcription, Genetic|Chromatin Immunoprecipitation|Genes, Reporter|Cyclic AMP Response Element-Binding Protein|Cell Differentiation|Up-Regulation|Phosphorylation|Transfection|CD68 antigen, human|Antigens, Differentiation, Myelomonocytic|CSF1 protein, human|M-CSF|Protein Binding|Antigens, CD 23 EVX2 15509224 Evol. Dev. 2004 10.1111/j.1525-142X.2004.04050.x 14 0 1 14 Humans|Mice|Animals|homeobox protein HOXA13|Homeodomain Proteins|Hox Genes|Transcription Factors|Body Patterning|Gene Expression Regulation, Developmental|Limb|Enhancer Elements, Genetic|Conserved Sequence|Mice, Transgenic|Amino Acid Sequence|Genital|Evx1 protein, mouse 33 EVX2 15254906 Dev. Dyn. 2004 10.1002/dvdy.20080 14 0 1 14 Animals|*Zebrafish|*Ameloblasts|*Morphogenesis|Odontogenesis|*Cell Differentiation|Tooth|In Situ Hybridization|Enamel Organ|Gene Expression Regulation, Developmental|*B Cells|Transcription Factors|DNA-Binding Proteins|evx1 protein, zebrafish|Homeodomain Proteins|Zebrafish Proteins|Evx2 protein, zebrafish 33 FERD3L 15210113 Cell 2004 10.1016/j.cell.2004.06.006 1365 2 124 19 Humans|Mice|Animals|CDH1 protein, human|E Cadherin|Twist-Related Protein 1|*Morphogenesis|Epithelial-Mesenchymal Transition|Cell Motility|Snail Family Transcription Factors|Neoplasm Invasiveness|Nuclear Proteins|Gene Expression Regulation, Neoplastic|Transcription Factors|Cell Line, Tumor|Mesoderm|Transcriptional Activation|Epithelial Cells|Signal Transduction|RNA, Small Interfering|Cell Adhesion 21 FILIP1 15509752 J. Neurosci. 2004 PMC6730158 10.1523/JNEUROSCI.2363-04.2004 54 0 4 40 Humans|FLNA protein, human|*Filamins|*Cell Polarity|*Neocortex|*Cell Movement|Periventricular Heterotopia|Neurons|Cell Shape|Neurogenesis|*Biophysical Phenomena|Short Interfering RNA 22 FOXJ3 15492844 Int. J. Oncol. 2004 0 1 0 127 Humans|Hedgehog Proteins|FOXR1 protein, human|Forkhead Box Proteins|FOXP4 protein, human|Base Sequence|Amino Acid Sequence|Genome, Human|Sequence Homology, Amino Acid|Transcriptional Activation|FOXE1 protein, human|FOXI1 protein, human|FOXF1 protein, human|FOXF2 protein, human|FOXM1 protein, human|Forkhead Box Protein M1|FOXQ1 protein, human|FOXJ2 protein, human|FOXL1 protein, human 21 GLIPR2 15123429 J. Mol. Biol. 2004 10.1016/j.jmb.2004.03.015 24 0 2 52 Animals|Humans|*Dimerization|Golgi Apparatus|Endoplasmic Reticulum|Membrane Proteins|Amino Acid Sequence|Protein Transport|pathogenesis-related proteins, plant|Plant Proteins|Sequence Homology, Amino Acid|Crystallography, X-Ray|Protein Binding|Transfection 21 GLIPR2 15039568 Acta Crystallogr. D Biol. Crystallogr. 2004 10.1107/S0907444904002136 4 0 0 52 Humans|*Crystallization|GOLPH3 protein, human|*Membrane Proteins|Crystallography, X-Ray|Protein Conformation|*Lipids|Cytosol|progesterone receptor B|*Receptors, Progesterone 21 GMFB 14980447 Biochim. Biophys. Acta 2004 10.1016/j.bbagen.2003.12.006 6 0 0 125 Animals|Rats|Humans|Female|Male|Rabbits|Young Adult|Adult|*Glia Maturation Factor beta|*Tissue Distribution|In Situ Hybridization|*Immunoassays|Blotting, Western|RNA, Messenger|Immunoassays, Enzyme 26 GPR26 15090189 Assay Drug Dev Technol 2004 10.1089/15406580360545053 11 0 2 71 GPRC5C protein, human|*Receptors, G-Protein-Coupled|*Signal Transduction Pathway|Ligands|Transfection 20 HMGN3 15082770 Mol. Cell. Biol. 2004 PMC387732 10.1128/mcb.24.9.3747-3756.2004 20 0 1 72 *Glycine Plasma Membrane Transport Proteins|HMGN3 protein, human|HMGN Proteins|Nucleosomes|Chromatin|TYRP1 protein, human|*Membrane Glycoproteins|Cell Lines|Gene Expression|RNA Splicing|Glycine 28 HTATSF1 15564463 J. Virol. 2004 PMC533906 10.1128/JVI.78.24.13522-13533.2004 36 21 1 139 Humans|*Positive Transcriptional Elongation Factor B|*HIV-1|*Phosphorylation|*Transcription Factor|*Histones|*Methylation|CDK9 protein, human|Cyclin-Dependent Kinase 9|tat Gene Products, Human Immunodeficiency Virus|RNA Polymerase II|HIV Long Terminal Repeat|Cyclin T|SPT5 transcriptional elongation factor|Transcriptional Elongation Factors|Transcription, Genetic|Cyclin-Dependent Kinases|Protein-Serine-Threonine Kinases|Cyclins 26 HTATSF1 15050687 Neurosci. Lett. 2004 10.1016/j.neulet.2004.02.012 18 1 1 139 Humans|*Astrocytes|*HIV-1|*Neurons|tat Gene Products, Human Immunodeficiency Virus|Apoptosis|Cell Proliferation|Cell Cycle Proteins|*Cytoplasm|CDC2 Protein Kinase|*Proteomics|Cell Line, Tumor 26 KLRC4 15140575 Mol. Immunol. 2004 10.1016/j.molimm.2004.01.004 9 3 0 16 Humans|KLRD1 protein, human|NK Cell Lectin-Like Receptor Subfamily D|Receptors, Natural Killer Cell|NK Cell Lectin-Like Receptor Subfamily C|Lectin, C-Type|NK Cells|Receptors, Immunologic|Histocompatibility Antigens Class I|Antigens, CD|Membrane Glycoproteins|Amino Acid Sequence 24 LGALS12 15575213 Zhongguo Zhong Yao Za Zhi 2004 2 0 0 461 Mice|Animals|*Bone Marrow|Medicine, Chinese Traditional|*Proteomics|Drugs, Chinese Herbal|Plants, Medicinal|Drug Combinations|Bone Marrow Cells|Whole-Body Irradiation|*Protein Processing, Post-Translational 24 LGALS12 15131127 J. Biol. Chem. 2004 10.1074/jbc.M401303200 21 2 2 461 Mice|Animals|*Adipogenesis|*Cell Differentiation|Adipocytes|*Signal Transduction|3T3-L1 Cells|CEBPB protein, human|CCAAT-Enhancer-Binding Protein-beta|Peroxisome Proliferator-Activated Receptor gamma|Adipose Tissue|RNA Interference|Cell Cycle|RNA, Messenger|Up-Regulation|Galectin 24 MTX3 15087125 Gene 2004 10.1016/j.gene.2004.01.005 1 0 0 133 Humans|Mice|Animals|*Zebrafish|*DNA, Complementary|Phylogeny|Sequences, Amino Acid|Zebrafish Proteins|Base Sequence|Sequence Alignment|Protein Structure, Secondary|Sequence Homology, Amino Acid|thrombospondin 4|Thrombospondins|Sequence Analysis, DNA 21 ncln 15554614 Inorg Chem 2004 10.1021/ic048976q 0 0 0 65 *Molybdenum|Molecular Structure|Spectroscopy|Crystallography, X-Ray|Models, Molecular|MoO2Cl2|Oxides|Organometallic Compounds|Xray Diffraction|Oxygen 21 ncln 15257293 EMBO J. 2004 PMC514924 10.1038/sj.emboj.7600307 14 2 0 65 Animals|Zebrafish|Zebrafish Proteins|*Signal Transduction|Nodal Protein|gamma-Secretase|Transforming Growth Factor beta|Body Patterning|Embryo, Nonmammalian|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Gene Expression Regulation, Developmental|Membrane Glycoproteins|Activin 21 OTOP1 15581873 Dev. Biol. 2004 PMC2522322 10.1016/j.ydbio.2004.09.001 25 0 0 24 Humans|Animals|Mice|*Zebrafish|*Otolithic Membrane|Zebrafish Proteins|*Organogenesis|*Embryonic Development|Calcite|Amino Acid Sequence|Ears|RNA, Messenger|Mutations|otopetrin 1 protein, human|Membrane Proteins|Phosphoproteins 23 Pl15 15536176 Sci. STKE 2004 10.1126/stke.2582004pl15 32 0 3 0 *Calcium Signaling|Calcium|Software|Algorithms|Computer Simulation 23 POU6F1 15177678 Gene 2004 10.1016/j.gene.2004.02.047 2 0 0 30 Humans|Animals|Mice|Rats|*DNA-Binding Proteins|Protein Isoforms|Alternative Splicing|Transcription Factors|Exons|Sequence Alignment|Base Sequence|Amino Acid Sequence|DNA, Complementary|Sequence Homology, Nucleic Acid|Cloning, Molecular|Blotting, Northern|Sequence Homology, Amino Acid|RNA, Messenger|Gene Expression Profiling|Sequence Analysis, DNA 34 PYHIN1 15122330 Oncogene 2004 10.1038/sj.onc.1207592 15 1 0 57 Humans|Mice|Animals|*Interferon|Mice, Nude|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin-Dependent Kinase Inhibitor p21|Cyclin-Dependent Kinases|CDC2-CDC28 Kinases|Cyclins|CDC2 Protein Kinase|Retinoblastoma Protein|Phosphorylation|Cyclin-Dependent Kinase 4|Cyclin-Dependent Kinase Inhibitor p27|Cell Nucleus|Microtubule-Associated Proteins 20 Resp18 15277470 Invest. Ophthalmol. Vis. Sci. 2004 10.1167/iovs.03-1391 19 0 2 423 Rats|Animals|*Retinal Ganglion Cells|*Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Retina|Gene Expression|Expressed Sequence Tag|Eye Proteins|Glaucoma 23 SCGB1D2 15590119 Toxicology 2004 10.1016/j.tox.2004.08.009 3 1 0 18 Male|Humans|Animals|Rats|*Fungicides, Industrial|fenarimol|Aromatase Inhibitors|Flutamide|Androgen Antagonists|*Pyrimidines|Androgens|Receptors, Androgen|Testosterone|Prostate|CLU protein, human|Clusterin|Orchiectomy|Androgen-Binding Protein|Secretoglobins|Luteinizing Hormone|Gene Expression|Rats, Wistar 156 SCGB1D2 15327891 Adv. Cancer Res. 2004 10.1016/S0065-230X(04)91005-6 41 14 2 18 Humans|*Proto-Oncogene Proteins c-raf|*Cell Signaling|NF-kappa B kinase|Phosphatidylethanolamine Binding Protein|*Apoptosis|NF-kappa B|MAP kinase kinase kinase 7|MAP Kinase Kinase Kinases|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Carrier Proteins|Androgen-Binding Protein|Antineoplastic Agents|Transcription Factors|Secretoglobins|Cancer|Extracellular Signal Regulated Kinases|Snail Family Transcription Factors 156 SCGB1D2 14750554 Am. J. Reprod. Immunol. 2004 10.1046/j.8755-8920.2003.00110.x 2 2 0 18 Male|Rats|Animals|*Prostatein|*Prostate|Secretoglobins|Androgen-Binding Protein|*Proteins|Uteroglobin|*Phagocytic Cell 156 TARBP1 15498776 J. Biol. Chem. 2004 10.1074/jbc.M408435200 15 3 1 41 Humans|*Positive Transcriptional Elongation Factor B|*HIV-1|*Binding, Competitive|*HIV Infections|HIV Long Terminal Repeat|tat Gene Products, Human Immunodeficiency Virus|Gene Expression Regulation, Viral|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|Transcription, Genetic|RNA, Viral|Promoter Regions, Genetic|Binding Sites 26 TBPL1 14967955 J. Reprod. Dev. 2004 10.1262/jrd.49.107 4 0 0 1191 Male|Mice|Animals|*Testis|*TATA Box Binding Protein-Like Proteins|*mRNA|*Spermatogenesis|Spermatids|Transcription Factors|DNA-Binding Proteins|*Transcription Factors, General|Blotting, Northern|5' Untranslated Regions 28 ZC3H12D 15220215 Diabetes 2004 10.2337/diabetes.53.7.1890 8 0 1 498 Humans|Diabetes Mellitus, Insulin-Dependent, 5|*Diabetes Mellitus, Type 1|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Small Ubiquitin-Related Modifier Proteins|Genotype|European Continental Ancestry Group|Nuclear Factor-Kappab|Pancreatic beta Cells|Intron|*Chromosome|TAB2 protein, human|Adaptor Proteins, Signal Transducing 20 ABTB1 14527422 Mol. Cell 2003 10.1016/s1097-2765(03)00341-1 121 2 2 20 *Ubiquitin|*Cullin Proteins|*BTB-POZ Domain|SKP Cullin F-Box Protein Ligases|Cell Cycle Proteins|ELOC protein, human|Elongin C|F-Box Proteins|Ubiquitin-Protein Ligases|Ubiquitins|Protein Binding|Peptide Synthases|TYRP1 protein, human|Skp1 Proteins|*Membrane Glycoproteins|Protein Structure, Tertiary|Amino Acid Sequence 31 ABTB1 12725910 Neurosci. Res. 2003 10.1016/s0168-0102(03)00024-5 2 2 0 20 Animals|Rats|*Adenovirus|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|*Apoptosis|*PC12 Cells|Transcription Factors|bcl-2-Associated X Protein|*Adenoviridae Infections|DNA-Binding Proteins|bcl-X Protein|Proto-Oncogene Proteins|Nerve Tissue Proteins|Repressor Proteins|*Brain|Neurons|*Mammals|Transfection 31 ABTB1 12556479 Mol. Cell. Biol. 2003 PMC141128 10.1128/mcb.23.4.1181-1195.2003 16 0 1 20 Animals|Drosophila melanogaster|*Drosophila Proteins|*Polycomb-Group Proteins|Homeodomain Proteins|Homeotic Gene|Drosophila|Polycomb Repressive Complex 1|Yeast Two-Hybrid Assay|Response Element|Promoter Regions, Genetic|Protein Binding|Amino Acid Sequence|trithorax protein, Drosophila 31 ADAM7 12890734 Biol. Reprod. 2003 10.1095/biolreprod.103.017566 2 0 0 20 Humans|Male|Mice|Animals|*Epididymis|*Receptor Protein-Tyrosine Kinases|Lipocalin|Knockout Mouse|Infertility, Male|Mice, Transgenic|Spermatozoa|Proto-Oncogene Proteins|Gene Chips|Excitatory Amino Acid Transporter 3|Membrane Transport Proteins|Fertility|Western Blots|Symporters|Immunohistochemistry|Crisp1 protein, mouse|Membrane Glycoproteins|Adam7 protein, mouse 24 ADAM7 12589653 Mol. Reprod. Dev. 2003 10.1002/mrd.10235 1 0 0 20 Male|Mice|Animals|*Diethylstilbestrol|*mRNA|*Epididymis|*Disintegrins|Estrogens, Non-Steroidal|Testis|In Situ Hybridization|Blotting, Northern|Oligonucleotide Array Sequence Analysis|Animals, Newborn|cDNA|Gene Expression|*Metalloproteases|Adam7 protein, mouse|Membrane Proteins|ADAM Proteins 24 CDKL2 14605869 Cell Tissue Res. 2003 10.1007/s00441-003-0828-8 8 0 0 100 Animals|Mice|Rabbits|*Lac Operon|Lurcher Mice|Purkinje Cells|Neurons|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|Cerebellar Nuclei|Glutamate|Brain|Geniculate Nucleus|Nerve Degeneration|Cerebral Cortex|Olfactory Bulb|Spinal Cord 20 CLIC6 14597386 Gene 2003 10.1016/s0378-1119(03)00830-8 9 0 0 37 Humans|Chlorocebus aethiops|Animals|Cattle|Cloning, Molecular|Amino Acid Sequence|Sequence Alignment|Luminescent Proteins|Blotting, Northern|Green Fluorescent Proteins|DNA, Complementary|Carrier Proteins|COS Cells|Sequence Homology, Amino Acid|Gene Expression|Chloride Channels|RNA, Messenger|Cytoplasm|Sequence Analysis, DNA|CLIC1 protein, human 21 CLIC6 14499480 Brain Res. Mol. Brain Res. 2003 10.1016/s0169-328x(03)00283-3 16 10 0 37 Animals|Rats|Chlorocebus aethiops|Humans|Rabbits|*Dopamine|HEK293 Cells|*Carrier Proteins|parchorin protein, Oryctolagus cuniculus|*Channel, Chloride|radixin|Membrane Proteins|Cell, COS|Phosphoproteins|Plasma Membrane|Cytoskeletal Proteins|Transfection|*Cytoplasm|cDNA Library|Amino Acid Sequence|Two-Hybrid System Techniques|Protein Binding|cDNA 21 CLIC6 12745921 Mol. Membr. Biol. 2003 10.1080/09687680210042746 36 0 2 37 Animals|CLIC4 protein, human|Channel, Chloride|parchorin protein, Oryctolagus cuniculus|Lipid Bilayers|Amino Acid Sequence|Ion Channel|*Cytoplasm|Cell Membrane|*Anions|GLRX protein, human|Glutaredoxin|Models, Molecular|Ion Transport|Phosphoproteins 21 CSMD2 12943675 Biochem. Biophys. Res. Commun. 2003 10.1016/s0006-291x(03)01555-9 20 0 2 9 Humans|Adult|Animals|Mice|Exons|Epilepsy, Myoclonic, Benign Adult Familial, Type 1|Epilepsies, Myoclonic|Amino Acid Sequence|Chromosome Mapping|*Human Chromosome|*Genes, Regulator|Open Reading Frames|Blotting, Northern|CSMD3 protein, human|Membrane Proteins|DNA Mutational Analysis|DNA, Complementary|RNA, Messenger|Sequence Homology, Amino Acid|CSMD3 protein, mouse|Nerve Tissue Proteins 20 CSMD2 12906867 Genomics 2003 10.1016/s0888-7543(03)00149-6 13 0 0 9 20 DAZ3 14639527 Am. J. Hum. Genet. 2003 PMC1181906 10.1086/381132 47 0 4 1 20 DNAJC14 12768437 J. Hum. Genet. 2003 10.1007/s10038-003-0012-8 3 0 0 65 Animals|Humans|Rats|*Cloning, Molecular|cDNA|Amino Acid Sequence|Base Sequence|Exons|Sequence Alignment|*Protein Domain|Introns|Open Reading Frames|Molecular Chaperone|cDNA Library|Sequence Homology, Amino Acid|Brain|Fetus|Liver 20 ETV3 12935928 Cancer Genet. Cytogenet. 2003 10.1016/s0165-4608(03)00065-7 9 0 0 1655 Child|Humans|*Hepatoblastoma|*Oligonucleotide Array Sequence Analysis|Liver Neoplasms|IGF2 protein, human|IGF-2|Liver|Gene Expression Profiling|*Oligonucleotides|*DNA|ETV3 protein, human|Proto-Oncogene Proteins c-ets|STMN1 protein, human|Stathmin|NAP1L1 protein, human|Nucleosome Assembly Protein 1 23 ETV3 12933588 Blood 2003 10.1182/blood-2003-01-0291 16 8 0 1655 Humans|Mice|Animals|interferon regulatory factor-8|*Fusion Proteins, bcr-abl|*Interferon Regulatory Factors|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Imatinib Mesylate|DNA-Binding Proteins|Gene Expression Regulation, Leukemic|Benzamides|Piperazines|Pyrimidines|Repressor Proteins|Transcription, Genetic|Neoplasm Proteins|Trans-Activators|Gene Expression Regulation|Messenger RNA|Phosphorylation|*Cell Cycle Checkpoints 23 EVX2 12732147 Cell 2003 10.1016/s0092-8674(03)00310-6 150 0 5 14 Mice|Animals|Genes, Homeobox|Homeodomain Proteins|Limb Buds|Enhancer Elements, Genetic|Gene Expression Regulation, Developmental|Transcription Factors|Mice, Transgenic|Limb|Multigene Family|Reporter Gene 33 EVX2 12622731 Evol. Dev. 2003 10.1046/j.1525-142x.2003.03021.x 8 1 3 14 Animals|Zebrafish|Zebrafish Proteins|*Gene Expression|Amino Acid Sequence|Gastrula|Homeodomain Proteins|Body Patterning|Transcription Factors|Base Sequence|Lineages, Cell|Sequence Homology, Amino Acid|Phylogeny|evx1 protein, zebrafish|Evx2 protein, zebrafish 33 fibronogen 12755278 Southeast Asian J. Trop. Med. Public Health 2003 0 1 0 0 Japan|Reproducibility of Results|Blood Coagulation Tests|*Quality Control|*Blood Coagulation|Activated Partial Thromboplastin Time|Time, Prothrombin|Laboratories|Quality Assurance, Health Care|Protein C|Fibrinogen|antithrombin III-protease complex|Antithrombin III|SERPINC1 protein, human|Peptide Hydrolases 23 glycolisis 12914410 Braz J Biol 2003 10.1590/s1519-69842003000100003 0 0 0 0 Animals|*Characiformes|malate dehydrogenase (decarboxylating)|*Malate Dehydrogenase|Kinetics|Isoenzymes|Hydrogen-Ion Concentration 23 glycolisis 12800488 Vestn. Akad. Med. Nauk SSSR 2003 0 0 0 0 Humans|*Nitric Oxide|Nitric Oxide Synthase|*Retinal Diseases|Nitroarginine|Retinal Vessels|Retina|Ischemia|Arginine|Apoptosis|Prostaglandins 23 GMFB 14518341 Langenbecks Arch Chir Suppl Kongressbd 2003 0 0 0 125 Rats|Animals|*Inducers, Angiogenesis|*Surgical Flaps|platelet-derived growth factor A|Platelet-Derived Growth Factor|Gene Therapy|*Fibroblasts|Neovascularization, Physiologic|Rats, Sprague-Dawley|*Gene Editing|Gene Transfer Techniques|Vascular Endothelial Growth Factor A|Adenoviridae|Necrosis|Transfections|Models, Animal 26 GMFB 12591611 Biochim. Biophys. Acta 2003 10.1016/s0167-4781(02)00627-9 8 1 0 125 Humans|Rats|Animals|glia maturation factor gamma|*Glia Maturation Factor|*Promoter Regions, Genetic|Base Sequence|Exon|Transcription, Genetic|Transcription Initiation Sites|Genes, Reporter|Introns|Cloning, Molecular|Transfections|5' Flanking Region|Binding Sites|cDNA|Luciferase|Cell Line 26 GRIN3B 14684433 Ann. N. Y. Acad. Sci. 2003 10.1196/annals.1300.003 13 0 0 31 Humans|Rats|Mice|Animals|*Receptors, Ionotropic Glutamate|COMT protein, human|Catechol O-Methyltransferase|*Genomics|Schizophrenia|Glutamate Receptor|Genome|Polymorphism, Genetic|Phenotype|Genetic Linkage|Genetic Variation|Chromosome Mapping|glutamate receptor ionotropic, AMPA 3|Receptors, AMPA|Synteny|BDNF protein, human|Brain-Derived Neurotrophic Factor 21 HMG20B 12809554 Biochem. J. 2003 PMC1223617 10.1042/BJ20030452 8 1 1 74 Humans|*Kinesin|BRCA2 protein, human|*BRCA2 Protein|Mitosis|Amino Acid Sequence|DNA-Binding Proteins|Interphase|Chromosomes|Yeast Two-Hybrid System|Sequence Homology, Amino Acid|HeLa Cells 22 HMG20B 12778069 Br. J. Cancer 2003 PMC2741050 10.1038/sj.bjc.6600919 23 0 1 74 Humans|Uveal melanoma|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Proto-Oncogene Proteins B-raf|*Uveal Neoplasms|Mutation|Exons|Polymerase Chain Reaction|BRAF protein, human 22 HMG20B 12761041 Hum. Mol. Genet. 2003 10.1093/hmg/ddg150 25 0 0 74 Animals|Humans|*Hair Cells, Auditory|*Hearing|Ear, Inner|Utricle|*Epithelium|*Regeneration|Cochlea|Hearing Loss|Epithelial Cell|*Hearing Tests|cDNA Microarrays|cDNA|Chickens|Transcription Factors|RNA, Messenger|CRIP2 protein, human|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 22 HTATSF1 12557056 Immunogenetics 2003 10.1007/s00251-002-0515-z 2 0 0 139 Humans|Mice|Rats|Animals|*Macaca mulatta|Genes, Class I|Genes, MHC Class II|*Biological Evolution|Gene Frequency|*Histocompatibility Antigens Class II|Major Histocompatibility Complex|Haplotypes|Base Sequence|Alleles|Phylogeny|Pseudogenes|Exons|Ring1 protein, rat|Ubiquitin-Protein Ligases|Polycomb Repressive Complex 1 26 IGIP 12607065 World J Surg 2003 10.1007/s00268-002-6756-z 2 0 0 16 Infant|Humans|Infant, Newborn|Retrospective Studies|*Infant, Very Low Birth Weight|Enterocolitis, Necrotizing|*Intestinal Obstruction|*Intestine, Small|Infant, Premature, Diseases|Infant, Premature|Intestinal Perforation|Enterostomy|Birth Weight|Survival Rate|*Abdominal Injuries|Dilatation, Pathologic 29 IGSF3 14656960 Genome Res. 2003 PMC403794 10.1101/gr.1549503 47 1 1 44 Humans|Animals|*Segmental Duplications, Genomic|DNA Shuffling|Gene Duplication|Schmid-Fraccaro syndrome|Chromosome Disorders|Alu Elements|Chromosome Mapping|*Chromosome Structures|Chromosome Aberrations|DiGeorge Syndrome|Recombination, Genetic|Pseudogenes|DNA|Aneuploidy|Chromosomes, Human, Pair 22|Eye Abnormalities 20 IGSF3 14600148 J. Biol. Chem. 2003 10.1074/jbc.M309631200 7 8 0 44 STAT1 protein, human|STAT1 Transcription Factor|*Interferon Type I|STAT2 Transcription Factor|Interferon-Stimulated Gene Factor 3|Trans-Activators|Phosphorylation|Interferon-Stimulated Gene Factor 3, gamma Subunit|Interferon-beta|*B Cells|Gene Expression Regulation|*Gene Expression|PTPN2 protein, human|TC-PTP|Signal Transduction|Tyrosine|Interferon-alpha 20 IMPG1 14691150 Invest. Ophthalmol. Vis. Sci. 2003 10.1167/iovs.03-0392 7 0 0 26 Macular dystrophy, concentric annular|*Macular Degeneration|Electroretinography|Genetic Linkage|Pedigree|Chromosome Mapping|Fluorescein Angiography|Visual Acuity|*Retinal Dystrophies|Eye Proteins|Genes, Dominant|Genotype 29 KLK9 14667505 Cancer Cell 2003 10.1016/s1535-6108(03)00273-3 62 0 2 20 Mice|Animals|*Transgenic Mouse|*Squamous Cell Carcinoma|Neovascularization, Pathologic|Skin Neoplasms|Peptide Library|Precancerous Conditions|Peptides|*Disease Models, Animal|Skin|Pancreatic Islet 36 KLK9 14667498 Cancer Cell 2003 10.1016/s1535-6108(03)00278-2 8 0 2 20 Mice|Animals|*Cell Surface Display Techniques|Peptide Library|Neovascularization, Pathologic|Peptides|*Neoplasms, Vascular Tissue|Endothelium, Vascular|*Vascular Neoplasms|Phage|*Book 36 LGALS12 12678492 Cell. Mol. Life Sci. 2003 10.1007/s000180300022 41 0 4 461 *Galectins|*Apoptosis|beta-galactoside|Galactosides|Cell Cycle|Cell Adhesion|Cell Division|*B-Lymphocytes|Cell Differentiation|Cell Migration|Chemotaxis|*Biological Phenomena 24 ncln 12526418 Inorg Chem 2003 10.1021/ic9910615 0 0 0 65 *Fluorides|*Uranium|*Chlorides|*Vibrations|Molecular Conformation|Quantum Theory|Spectrum Analysis, Raman|Models, Molecular|Thermodynamics|*Chlorine 21 PARM1 12859648 Lett. Appl. Microbiol. 2003 10.1046/j.1472-765x.2003.01322.x 0 0 0 49 *Pseudomonas aeruginosa|n-tetradecane|dibenzothiophene|*Alkanes|*Thiophenes|Rhodococcus|DNA Transposable Elements|Cloning, Molecular|Genes, Bacterial|Sulfur 20 PARM1 12772192 Prostate 2003 10.1002/pros.10254 8 0 0 49 Humans|Male|*Prostate|*Androgens|Prostatic Neoplasms|*Cell Line|Androgen-Binding Protein|Gene Expression|Tumor Cells, Cultured|Telomerase|RNA, Messenger 20 pkd1l1 14650760 S D J Med 2003 0 0 0 17 Pregnancy|Humans|Adult|Male|Infant|Female|Infant, Newborn|*Kidney, Polycystic|Polycystic Kidney, Autosomal Dominant|Kidney|Prenatal Diagnosis|Ultrasonography, Prenatal|Ultrasonography|Genetic Linkage|Pedigree 20 POU6F1 14612392 Mol. Cell. Biol. 2003 PMC262677 10.1128/mcb.23.23.8462-8470.2003 27 2 0 30 Animals|CTNNB1 protein, human|*beta Catenin|*Wnt Signaling Pathway|Transcription Factors|T-Cell Factors|DNA-Binding Proteins|Wnt Proteins|Trans-Activators|*Cell Nucleus|Lymphoid Enhancer-Binding Factor 1|Proto-Oncogene Proteins|Zebrafish Proteins|Wnt1 Protein|Repressor Proteins|Transcriptional Activation|APC protein, human|Adenomatous Polyposis Coli Protein|Drosophila 34 SCAMP2 12670959 J. Biol. Chem. 2003 10.1074/jbc.M301652200 46 1 0 316 MARCKS protein, human|*Myristoylated Alanine-Rich C Kinase Substrate|*Phenylalanine|*Peptides|Proteins, Membrane-Associated|Lipid Bilayers|Phosphatidyl Choline|Intracellular Signaling Peptides and Proteins|Plasma Membranes|Static Electricity|Phosphatidylglycerols|Protein Structure, Tertiary|Phosphatidylinositol 4,5-Diphosphate|Protein Binding|Amino Acid Sequence|*Membranes|Binding Sites|*Hydrophobic and Hydrophilic Interactions 26 SCGB1D2 14666997 Birth Defects Res. B Dev. Reprod. Toxicol. 2003 10.1002/bdrb.10030 1 0 0 18 Male|Humans|Rats|Animals|*Prostate|*Gn-RH|*Antiandrogens|Flutamide|Androgens|*Gene Expression|Orchiectomy|Testosterone|Luteinizing Hormone|CLU protein, human|Clusterin|Androgen-Binding Protein|Secretoglobins|Dichlorodiphenyl Dichloroethylene 156 TBPL1 12682363 Nucleic Acids Res. 2003 PMC153743 10.1093/nar/gkg315 12 4 0 1191 Humans|Animals|Mice|*Transcription Factor TFIIA|*TATA Box Binding Protein-Like Proteins|*DNA Nucleotidylexotransferase|*Promoter Regions, Genetic|TATA Box|TATA-Box Binding Protein|Transcription Factors|Transcription, Genetic|Activation, Transcription|Protein Binding|*Vertebrate|HeLa Cells|*DNA-Directed DNA Polymerase 28 TMEFF1 14563676 Genes Dev. 2003 PMC280611 10.1101/gad.1127703 20 4 0 69 Animals|*Transforming Growth Factor beta|*Signal Transduction|Nodal Protein|Membrane Proteins|Activin|Activin Receptors, Type I|GPI-Linked Proteins|Neoplasm Proteins|Epidermal Growth Factor|Activin Receptor-like Kinase|Xenopus Proteins|Xenopus laevis|Transcription Factors|Homeodomain Proteins|Protein Binding|Activin Receptors, Type II|Ectoderm 26 TMEFF1 12875894 Life Sci. 2003 10.1016/s0024-3205(03)00514-9 8 10 0 69 Humans|*Cytokines|NF-kappa B|TNFalpha|Signal Transduction|DNA-Binding Proteins|Phosphorylation|IL1B protein, human|Interleukin-1beta|Electrophoretic Mobility Shift Assay|Epidermal Growth Factor|RNA, Messenger 26 TMEFF1 12743596 Oncogene 2003 10.1038/sj.onc.1206351 7 0 0 69 Humans|*Brain Tumors|Glioma|enhanced green fluorescent protein|Green Fluorescent Proteins|Membrane Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Membrane Glycoproteins|Signal Transduction|RNA, Messenger 26 TMEFF1 12729735 J. Mol. Biol. 2003 10.1016/s0022-2836(03)00404-2 6 6 0 69 Humans|Male|Prostate|Membrane Proteins|Neoplasm Proteins|*Promoter Regions, Genetic|Prostatic Neoplasms|Transcription Factors|Tumor Cells, Cultured|Cell Transformation, Neoplastic|Binding Sites|Oncogenesis|Epidermal Growth Factor|Luciferase|Transfection|TMEFF2 protein, human 26 TMEFF1 12618130 Dev. Biol. 2003 10.1016/s0012-1606(02)00075-1 18 23 0 69 Animals|recombinant human bone morphogenetic protein-2|*Transforming Growth Factor beta|Bone Morphogenetic Protein|Mesoderm|*Signal Transduction|Activin|Nodal Protein|Xenopus Proteins|Xenopus laevis|Follistatin|Germ Layer|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Membrane Protein|Amino Acid Sequence|Bone Morphogenetic Protein 2 26 ZNF91 12738986 Int. J. Oncol. 2003 15 1 0 55 Humans|Mice|Animals|Leukocytes, Mononuclear|*Leukemia, Myeloid, Acute|Transcription Factors|Zinc Finger|cDNA Microarray|DNA-Binding Proteins|Neoplasm Proteins|Leucine Zipper|Biomarkers, Tumor|Amino Acid Sequence|Downregulation|ZFP91 protein, human|Ubiquitin-Protein Ligases 26 ABTB1 12163020 Biochem. Biophys. Res. Commun. 2002 10.1016/s0006-291x(02)00850-1 6 0 1 20 Humans|Male|Animals|Mice|*Testis|*Zinc Finger|Transcription Factors|DNA-Binding Proteins|Amino Acid Sequence|Repressor Proteins|Transcription, Genetic|Base Sequence|In Situ Hybridization|Cloning, Molecular|Sequence Alignment|Cell Nucleus|*Brain|DNA, Complementary|Sequence Homology, Amino Acid|Splicings, Alternative|RNA, Messenger|Embryo, Mammalian 31 ABTB1 11973274 Development 2002 42 0 0 20 Animals|*Drosophila|*BTB-POZ Domain|Drosophila Proteins|DNA-Binding Proteins|Transcription Factors|*Morphogenesis|Drosophila melanogaster|Genes, Insect|Gene Expression Regulation, Developmental|Nuclear Protein|Amino Acid Sequence|Sequence Homology, Amino Acid 31 ABTB1 11959095 FEBS Lett. 2002 10.1016/s0014-5793(02)02456-0 2 5 0 20 Humans|Animals|Mice|KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|NF-E2-Related Factor 2|DNA-Binding Proteins|Amino Acid Sequence|Zinc Fingers|Carrier Proteins|Transcription, Genetic|Repressor Proteins|Microfilament Proteins|Protein Structure, Tertiary|Protein Binding|Sequence Homology, Amino Acid|DNA, Complementary|Cloning, Molecular|actin kinase|Protein-Serine-Threonine Kinases|Adenosine Triphosphate 31 ABTB1 11906783 Neuroscience 2002 10.1016/s0306-4522(01)00518-8 6 0 0 20 Animals|Rats|*Cocaine|*Isoforms|*Gene Expression Regulation|*Brain|Nerve Tissue Proteins|Repressor Proteins|Transcription, Genetic|Nucleus Accumbens|Neurons|mRNA|Transfection|Blotting, Western 31 ADAM7 12037602 Immunogenetics 2002 10.1007/s00251-002-0430-3 19 0 4 20 Humans|Mice|Animals|decysin|ADAM Proteins|*Gene Cluster|Amino Acid Sequence|*Chromosome Structures|Membrane Glycoproteins|Sequence Homology, Amino Acid|Gene Duplication|ADAM28 protein, human|Adam7 protein, mouse|Membrane Proteins|Adam28 protein, mouse|Adamdec1 protein, mouse 24 AP3M2 12119359 J. Cell Biol. 2002 PMC2173125 10.1083/jcb.200203103 53 19 0 40 *Phosphoinositides|Clathrin|*Binding Site|*Endocytosis|Adaptor Protein Complex 2|Adaptor Protein Complex 1|Membrane Proteins|Adaptor Protein Complex mu Subunits|Adaptor Proteins, Vesicular Transport|Adaptor Protein Complex alpha Subunits|Adaptor Protein Complex 3|Carrier Proteins|Clathrin-Coated Vesicles|Protein Binding|Vesicular Transport Proteins|Amino Acid Sequence|Cell Membrane|*Protein Domains 25 AP3M2 12086608 Cell 2002 10.1016/s0092-8674(02)00735-3 213 6 5 40 Adaptor Protein Complex 2|Adaptor Protein Complex mu Subunits|Coated Pits, Cell-Membrane|Clathrin|Endocytosis|Adaptor Protein Complex 1|Adaptor Protein Complex 3|Plasma Membrane|Adaptor Proteins, Vesicular Transport|Protein Transport|Membrane Proteins|Binding Sites|Protein Binding|Phosphorylation 25 AP3M2 12032142 J. Biol. Chem. 2002 10.1074/jbc.M200522200 40 1 0 40 Humans|*Adaptor Protein Complex 2|*ATPase|Adaptor Protein Complex alpha Subunits|nef Gene Products, Human Immunodeficiency Virus|Adaptor Protein Complex 1|Clathrin|Adaptor Protein Complex 3|Adaptor Proteins, Vesicular Transport|CD4 Antigens|Protein Binding|Membrane Proteins|Simian Immunodeficiency Virus|Endocytosis|HIV-1|Down-Regulation|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 25 CDC42EP4 12479805 Dev. Cell 2002 10.1016/s1534-5807(02)00366-0 186 1 11 127 Animals|*Septins|*Actins|anillin|Contractile Proteins|actin-binding protein anillin, human|Microfilament Proteins|*Mammals|Cytokinesis|Cell Cycle Proteins|Cytoskeleton|Cell Division|Amino Acid Sequence|Protein Binding 20 CDC42EP4 12446710 J. Biol. Chem. 2002 10.1074/jbc.M209701200 65 0 5 127 Animals|*Septins|Saccharomyces cerevisiae|*Cytoskeleton|Saccharomyces cerevisiae Proteins|GTP-Binding Proteins|Guanosine Triphosphate|Cell Cycle Proteins|Protein Binding|Amino Acid Sequence|Binding Sites|*Dimerization|Carrier Proteins|Cell Division 20 CLIC6 12226712 Mamm. Genome 2002 10.1007/s00335-001-2157-0 4 0 0 37 Humans|*Genome, Human|Evolution, Molecular|Gene Duplication|Multigene Family|Phylogeny|Amino Acid Sequence|Sequence Alignment|Chromosome Mapping|Genomics 21 CPA6 11836249 J. Biol. Chem. 2002 10.1074/jbc.M112254200 24 0 0 44 Male|Humans|Animals|Mice|Amino Acid Sequence|Base Sequence|cDNA|Gene Library|Cloning, Molecular|Chromosome Mapping|Sequence Alignment|In Situ Hybridization|Proteins|Blotting, Northern|Sequence Homology, Amino Acid|Gene Cluster|Testis|mRNA|Genome, Human 24 DGCR2 12176937 Genome Res. 2002 PMC186637 10.1101/gr.269102 106 0 3 182 Animals|Male|*cDNA|*Drosophila melanogaster|*Drosophila|cDNA Libraries|Expressed Sequence Tags|Genes, Insect|Chromosome Mapping|Cloning, Molecular|Sequence Analysis, DNA|Base Sequence|Gene Expression Profiling|Genome 22 DGCR2 12110949 J. Mol. Med. 2002 10.1007/s00109-002-0331-9 11 0 0 182 Humans|Child|10p Deletion Syndrome (Partial)|*Chromosome Deletion|Barakat syndrome|Hypoparathyroidism|DiGeorge Syndrome|*Chromosome Disorders|Nephrosis|Hearing Loss, Sensorineural|GATA3 protein, human|GATA3 Transcription Factor|*Chromosomes, Human, Pair 10|Cytogenetic Analysis|Kidney|Chromosomal Aberration|Congenital Heart Defect|Haploinsufficiency|*Heart|*DNA Mutational Analysis 22 DGCR2 11807885 Am. J. Med. Genet. 2002 10.1002/ajmg.10106 0 0 0 182 Humans|*DiGeorge Syndrome|*Primed In Situ Labeling|In Situ Hybridization, Fluorescence|Angelman Syndrome|Shprintzen Golberg craniosynostosis|*Arachnodactyly|Prader-Willi Syndrome|*Marfan Syndrome|*Craniosynostoses|SNRPN|Chromosome Deletion|Oligonucleotide Primers 22 DGCR6 12014644 Anticancer Res. 2002 32 0 0 67 Humans|Mice|Animals|Gene Chip|Gene Expression Regulation, Neoplastic|Up-Regulation|Downregulation|Gene Expression Profiling|*Cell Lines|*Neoplastic Processes|Nude Mouse|Tumor Cells, Cultured|Transcription, Genetic|Transcription Factors|Signal Transduction|Osteopontin 24 DNAJC14 12446598 Endocrinology 2002 10.1210/en.2002-220679 21 2 0 65 Animals|Chlorocebus aethiops|*Angiotensin II|*Caveolin 1|*Signal Transduction|Caveolae|*Protein Transport|Plasma Membrane|Receptor, Angiotensin, Type 1|COS Cells|DRD1 protein, human|Dopamine D1 Receptor|Inositol Phosphates|Endocytosis|Kinetics|Transfection|*Cell Movement 20 ETV3 12007404 Cell 2002 10.1016/s0092-8674(02)00714-6 39 20 1 1655 Transcription Factors|Cell Cycle Proteins|Cell Cycle|Retinoblastoma-Like Protein p130|Retinoblastoma Protein|Retinoblastoma-Like Protein p107|Phosphoproteins|E2F Transcription Factors|Retinoblastoma-Binding Protein 1|Cell Division|Repressor Proteins|Promoter Regions, Genetic|Carrier Proteins|Transcription Factor DP1|Cell Differentiation|*Macrophage|Protein Binding|Phosphorylation 23 ETV3 11783006 Genesis 2002 10.1002/gene.10018 6 0 0 1655 Animals|*Caenorhabditis elegans|*Genes, Homeobox|NK 2|Caenorhabditis elegans Proteins|*Pharyngeal Muscle|Homeodomain Proteins|Transcription Factors|Enhancer Elements, Genetic|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Morphogenesis|Pharynx|Base Sequence|Promoter Regions, Genetic|Amino Acid Sequence 23 EVX2 12432383 Nature 2002 10.1038/nature01189 67 0 4 14 Hox Genes|*Limbs|Homeodomain Proteins|Enhancer Elements, Genetic|Gene Expression Regulation, Developmental|Multigene Family|In Situ Hybridization 33 EVX2 11778160 Am. J. Hum. Genet. 2002 PMC384929 10.1086/338921 19 0 2 14 Humans|Female|Child|Mice|Animals|Syndactyly, type 2|*Syndactyly|*Transcription Factors|*Genes, Homeobox|Ectrodactyly|Limb Deformities, Congenital|Split hand foot deformity|Homeodomain Proteins|Foot Deformities, Congenital|Polydactyly|Hand Deformities, Congenital|Chromosome Deletion|Pedigree|Mutations|HOXD9 protein, human|Neoplasm Proteins|HOXD13 protein, human|Hoxd13 protein, mouse 33 FERD3L 12217327 Dev. Biol. 2002 10.1006/dbio.2002.0753 14 0 1 19 Mice|Animals|ASCL1 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Helix-Loop-Helix Motifs|Drosophila|Transcription, Genetic|Binding Site|Activation, Transcriptional|Nuclear Proteins|Drosophila Proteins|Twist-Related Protein 1|Mesoderm|Amino Acid Sequence|Base Sequence|Nervous System|Cell Differentiation|Sequence Homology, Amino Acid 21 fibronogen 11881155 Tsitologiia 2002 0 1 0 0 ICAM1 protein, human|*Intercellular Adhesion Molecule-1|*Macrophage-1 Antigen|Cell Adhesion|Monocytes|Fibrinogen|Fibrin Fibrinogen Degradation Products|Plasmin|Integrins|*Tissue Adhesions|Endothelium, Vascular|Up-Regulation|Cell Line 23 GLIPR2 12137952 Gene 2002 10.1016/s0378-1119(02)00703-5 5 0 1 52 Male|Adult|Humans|Animals|Mice|Amino Acid Sequence|Exons|cDNA|Sequence Alignment|Introns|Base Sequence|Cloning, Molecular|DNA|Conserved Sequence|Sequence Homology, Amino Acid|Gene Expression Profiling|Sequence Analysis, DNA|Nuclear Proteins|mRNA|Membrane Proteins|Phylogeny|RECK protein, human|GPI-Linked Proteins 21 GMFB 11935129 Surgery 2002 10.1067/msy.2002.121887 3 3 2 125 Rats|Animals|*Platelet Derived Growth Factor B|*Ischemia|*Surgical Flaps|Genetic Therapy|Neovascularization, Physiologic|*Fibroblasts|*Gene Editing|Gene Transfer Techniques|Vascular Endothelial Growth Factor A|*Neovascularization, Pathologic|Graft Survival|Models, Animal|*Islands 26 HMG20B 12083780 Biochem. Biophys. Res. Commun. 2002 10.1016/s0006-291x(02)00625-3 1 0 0 74 Male|Humans|*Prostate Cancer|Prostate|Benign Prostatic Hyperplasia|Immunohistochemistry|Splicings, Alternative 22 HMG20B 12083779 Biochem. Biophys. Res. Commun. 2002 10.1016/s0006-291x(02)00624-1 0 0 0 74 Humans|Male|*Genes, BRCA2|BRCA2 protein, human|*BRCA2 Protein|*DNA, Complementary|DNA Binding Protein|*Splicings, Alternative|*Splicings, Protein|Transcription Factors|Amino Acid Sequence|Base Sequence|Neoplasm Proteins|Cloning, Molecular|Prostate Cancer|Tumor Cells, Cultured 22 HMG20B 12032298 Proc. Natl. Acad. Sci. U.S.A. 2002 PMC124246 10.1073/pnas.112008599 113 2 4 74 Humans|*Histone Deacetylases|DNA Binding Protein|HDAC1 protein, human|Histone Deacetylase 1|Transcription Factors|Histones|Repressor Proteins|Mi-2 Nucleosome Remodeling and Deacetylase Complex|Nucleosome|Transcription, Genetic|Nerve Tissue Proteins|*Neurons|Regulatory Sequences, Nucleic Acid|Chromatin Immunoprecipitation|Protein Binding 22 HMG20B 11997092 Biochim. Biophys. Acta 2002 10.1016/s0167-4781(01)00373-6 2 3 0 74 Humans|Mice|Animals|*High Mobility Group Proteins|DNA-Binding Proteins|Base Sequence|Amino Acid Sequence|DNA|Chromatin|DNA, Complementary|Cloning, Molecular|Electrophoretic Mobility Shift Assay|Sequence Homology, Amino Acid|Gene Expression|Open Reading Frame 22 HTATSF1 11853694 Biochem. Pharmacol. 2002 10.1016/s0006-2952(01)00909-1 0 1 0 139 Mice|Animals|Cyp2a5 protein, mouse|Cytochrome P450 Family 2|Aryl Hydrocarbon Hydroxylases|CYP2A6 protein, human|Coumarin 7 Hydroxylase|Cytochrome P-450 Enzyme System|Hepatocytes|Liver|Phenobarbital|mRNA|pyrazole|Pyrazoles|Cells, Cultured|Upregulation|*Apoptosis 26 HTATSF1 11780068 Nature 2002 10.1038/414929a 134 3 4 139 Humans|*Splicing Factors|Positive Transcriptional Elongation Factor B|RNA Polymerase II|HIV Long Terminal Repeat|Cyclin T|tat Gene Products, Human Immunodeficiency Virus|Transcription, Genetic|Transcription Factors|Protein-Serine-Threonine Kinases|Gene Expression Regulation, Viral|Human immunodeficiency virus 1|Cyclins|Nuclear Proteins|Promoter Regions, Genetic|Spliceosomes 26 IMPG1 11991949 J. Biol. Chem. 2002 10.1074/jbc.M201279200 2 0 0 26 Humans|Mice|Animals|*Retinal Rod Photoreceptor Cells|*Retinal Cone Photoreceptor Cells|*Sialoglycoproteins|Retina|*Cloning, Molecular|*Glycoprotein|Photoreceptor Cells, Vertebrate|Amino Acid Sequence|*Chickens|Eye Proteins|*Extracellular Matrix|Base Sequence|Proteoglycans|cDNA|Glycoconjugates 29 PDE3B signalling 11872660 Diabetes 2002 10.2337/diabetes.51.3.631 8 3 0 0 Mice|Humans|Animals|*3T3-L1 Cells|*Lipolysis|*Insulin|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Adipocytes|*Insulin, Regular, Human|3',5'-Cyclic-AMP Phosphodiesterases|Protein Kinase A|*Ceramides|Troglitazone|Cyclic AMP|Downregulation|Hypoglycemic Agents|Phosphorylation|Insulin Resistance|Isoproterenol|Cell Differentiation 21 PDE3B signalling 11812651 Cell. Signal. 2002 10.1016/s0898-6568(01)00238-8 45 11 3 0 Rats|Animals|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Protein Phosphatase 2|Okadaic Acid|tautomycin|Pyrans|Phosphorylation|Spiro Compounds|Signal Transduction|*Adipocytes|Protein Phosphatase 1|Oxazoles|Enzyme Inhibitors|*Biochemical Phenomena|Insulin|Phosphodiesterase 3B 21 pkd1l1 12411743 Nephron Exp. Nephrol. 2002 10.1159/000066648 2 0 0 17 Humans|polycystic kidney disease 1 protein|*TRPP Cation Channels|Polycystic Kidney, Autosomal Dominant|Calcium Channels|Phosphoproteins|Membrane Glycoproteins|Kidney 20 pkd1l1 11863367 Genomics 2002 10.1006/geno.2002.6719 12 2 1 17 Male|Humans|Animals|Mice|In Situ Hybridization, Fluorescence|polycystic kidney disease 2 protein|Polycystins|polycystic kidney disease 1 protein|PKD1L1 protein, human|Amino Acid Sequence|Potter Type III Polycystic Kidney Disease|*Polycystic Kidney Diseases|Polycystic Kidney, Autosomal Dominant|Exons|Chromosome Mapping|cDNA|Sequence Homology, Amino Acid|Cloning, Molecular|Genes, Regulator 20 Pl15 12372853 Sci. STKE 2002 10.1126/stke.2002.153.pl15 0 0 2 0 Phosphorylation|Electrophoresis, Polyacrylamide Gel|Substrate Specificity|Protein Kinases|Signal Transduction|Proteins|polyacrylamide gels|Acrylic Resins|Sodium Dodecyl Sulfate|*Biological Assay|Cell Differentiation 23 TMEFF1 12175877 Int. J. Dev. Neurosci. 2002 10.1016/s0736-5748(02)00055-2 13 0 2 69 Mice|Cats|Animals|Dendrites|Pyramidal Cells|GM2 Ganglioside|Cerebral Cortex|Neurons|*Biochemical Phenomena|*Organogenesis|*Cognition|Integral Membrane Protein 26 ZNF91 12206807 Neuromuscul. Disord. 2002 10.1016/s0960-8966(02)00093-7 44 2 2 55 Male|Female|Humans|Mice|Animals|*Transcriptome|Dystrophin|Mice, Inbred mdx|Duchenne Muscular Dystrophy|Muscular Dystrophy, Animal|Muscle, Skeletal|IGF2 protein, human|IGF-2|Gene Chip|IGF1 protein, human|IGF-1|Regeneration|Upregulation|Signal Transduction 26 ABTB1 11744704 J. Biol. Chem. 2001 10.1074/jbc.M110023200 29 0 6 20 Mice|Animals|*BTB-POZ Domain|*Zinc Finger|DNA-Binding Proteins|*Isoforms|*Cell Nucleus|Transcription Factors|DNA Sequence|Binding Site|*Cell Differentiation|*Neurons|Transcription, Genetic|Repressor Proteins|Amino Acid Sequence|*Cerebellum|Blotting, Northern|Transfection|*Hippocampus|Protein Binding 31 ABTB1 11543621 Dev. Biol. 2001 10.1006/dbio.2001.0358 12 2 1 20 Humans|Animals|*Drosophila|*BTB-POZ Domain|*Factor II|*Transcription Factors|Drosophila Proteins|DNA-Binding Proteins|Repressor Proteins|Zinc Fingers|Transcription, Genetic|Binding Sites|Amino Acid Sequence|Protein Binding|Protein Structure, Tertiary|Sequence Homology, Amino Acid|5-((4,6-dichloro-1,3,5-triazin-2-yl)amino)fluorescein 31 ADAM7 11514362 Biol. Reprod. 2001 10.1095/biolreprod65.3.944 2 0 0 20 Animals|Male|Humans|*Epididymis|*DNA, Complementary|*Disintegrins|Amino Acid Sequence|ADAM Proteins|Testis|Base Sequence|Blotting, Northern|Membrane Proteins|Cloning, Molecular|Fertilins|Membrane Glycoproteins|Peptides|Sperm-Egg Interaction|Spermatozoa|Spermatogenesis|Sequence Homology, Amino Acid 24 AP3M2 11591131 Mol. Cell. Neurosci. 2001 10.1006/mcne.2001.1022 18 3 0 40 Animals|Mice|doublecortin protein|Microtubule-Associated Proteins|Adaptor Protein Complex 2|Adaptor Protein Complex 1|Clathrin|Adaptor Protein Complex mu Subunits|Adaptor Proteins, Vesicular Transport|Adaptor Protein Complex 3|Saccharomyces cerevisiae|Membrane Proteins|Carrier Proteins|Phosphoproteins|Protein Binding|Amino Acid Sequence|Golgi Apparatus|Nervous System 25 AP3M2 11516654 Curr. Biol. 2001 10.1016/s0960-9822(01)00240-8 53 3 0 40 *Phosphorylation|*Threonine|*Endocytosis|Coated Pits, Cell-Membrane|Adaptor Protein Complex 2|Clathrin|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 1|Adaptor Protein Complex alpha Subunits|Adaptor Protein Complex 3|Clathrin-Coated Vesicles|Adaptor Proteins, Vesicular Transport|Membrane Proteins|Protein Binding|Protein Transport|Transferrin 25 AP3M2 11369939 Nat. Neurosci. 2001 10.1038/88404 100 0 6 40 *Receptors, N-Methyl-D-Aspartate|*Tyrosine|Adaptor Protein Complex 2|Adaptor Protein Complex 1|Clathrin|Adaptor Proteins, Vesicular Transport|Excitatory Amino Acid Antagonists|Membrane Proteins|Signal Transduction 25 CDC42EP4 11584266 Nat. Cell Biol. 2001 10.1038/ncb1001-861 74 4 8 127 Animals|*Septins|cdc42 GTP-Binding Protein|Protein Binding|Amino Acid Sequence|TYRP1 protein, human|*Membrane Glycoproteins|Protein Structure, Tertiary|Signal Transduction|Binding Sites|Sequence Homology, Amino Acid|Models, Molecular 20 CDC42EP4 11264665 Eur. J. Neurosci. 2001 10.1046/j.0953-816x.2001.01466.x 2 0 1 127 Humans|MARCKS protein, human|*Myristoylated Alanine-Rich C Kinase Substrate|*Noradrenaline|*Neuroblastoma|Phorbol 13-Acetate, 12-O-Tetradecanoyl|Membrane Proteins|Carbachol|Protein Kinase C|Tumor Cells, Cultured|*Biological Transport|Calcium|Potassium 20 CDC42EP4 11185749 J. Hum. Genet. 2001 10.1007/s100380070012 2 0 0 127 Adult|Animals|Mice|Humans|In Situ Hybridization, Fluorescence|*Gene Expression|Chromosome Mapping|Amino Acid Sequence|cDNA|Cloning, Molecular|cdc42 GTP-Binding Protein|rho GTPases|Sequence Homology, Amino Acid|Polymerase Chain Reaction|*Chromosome|*Sequence Analysis 20 CPA6 11735539 J. Org. Chem. 2001 10.1021/jo016051b 1 0 0 44 *Porphyrins|Molecular Structure|Quantum Theory|Pyrroles|Models, Molecular|Crystallography, X-Ray|*Confusion 24 CRYZ 11348717 Vaccine 2001 10.1016/s0264-410x(01)00061-5 0 0 0 488 Humans|*Klebsiella|*Pseudomonas|*Serogroup|*Infusions, Intravenous|*Healthy Volunteers|*Immunoglobulin|Klebsiella Infections|Antibodies, Bacterial|O Antigens|ELISA 164 DGCR2 11589220 J. Hum. Genet. 2001 10.1007/s100380170029 2 0 0 182 Humans|Mice|Animals|*DiGeorge Syndrome|Chromosome Mapping|Single Nucleotide Polymorphism|Introns|3' Untranslated Region|Exons|Sequence Analysis, DNA|5' Untranslated Region|Polymerase Chain Reaction|*Chromosome Structures|Nucleotides 22 EVX2 11543613 Dev. Biol. 2001 10.1006/dbio.2001.0375 16 0 1 14 Animals|*Lancelets|*Hindbrain|*Mesencephalon|Phylogeny|Homeodomain Proteins|Evolution, Molecular|Vertebrates|Amino Acid Sequence|Body Patterning|Gene Expression Regulation, Developmental|Sequence Homology, Amino Acid 33 FERD3L 11472856 Mech. Dev. 2001 10.1016/s0925-4773(01)00437-3 4 0 1 19 Humans|Male|Mice|Animals|*Drosophila|*Transcription Factor|Caenorhabditis elegans|Helix-Loop-Helix Domain|Basic Helix-Loop-Helix Transcription Factors|*Central Nervous System|Drosophila Proteins|Homeodomain Proteins|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Amino Acid Sequence|Base Sequence|Neurons|Embryo, Nonmammalian|Sequence Homology, Amino Acid 21 fibronogen 11477815 Zhongguo Zhong Xi Yi Jie He Za Zhi 2001 1 0 0 0 Humans|*Noninsulin Dependent Diabetes Mellitus|*Qi|Yin Deficiency|*Kidney|Erythrocyte Deformability|Blood Viscosity|Hemorrheology|Drugs, Chinese Herbal|*Tablets|*Erythrocyte|Erythrocyte Membrane|Sodium-Potassium-Exchanging ATPase 23 fibronogen 11265801 J Indian Med Assoc 2001 0 0 0 0 Humans|*Coronary Artery Disease|Cross-Sectional Studies|Atherosclerosis|Coronary Thrombosis|Endothelium, Vascular|SERPINE1 protein, human|PAI-1|Risk Factors 23 glycolisis 11154851 Int. J. Dev. Neurosci. 2001 10.1016/s0736-5748(00)00045-9 0 0 0 0 Rats|Animals|*Kinase, BB Creatine|*Chickens|*Isoenzymes|Creatine Kinase|MM Creatine Kinase|*Cytosol|MB Creatine Kinase|Phosphocreatine|Brain|Creatine|Aging|Neurons|Cells, Glial|Mitochondria|Myocardium|Phosphorylation|Rhode Island 23 glycosis 11198117 Arkh. Patol. 2001 0 0 0 0 Humans|*HIV Infections|HIV Seronegativity|*Addiction, Drug|HIV Seropositivity|*Brain 21 GMFB 11687281 Brain Res. Mol. Brain Res. 2001 10.1016/s0169-328x(01)00252-2 3 0 0 125 Animals|Rats|glia maturation factor gamma|*Glia Maturation Factor|In Situ Hybridization|mRNA|Blotting, Northern|Glia|Retina|Neurons 26 GMFB 11435704 Cytogenet. Cell Genet. 2001 10.1159/000056919 2 0 0 125 Humans|Pregnancy|Female|Animals|Mice|*Glia Maturation Factor beta|cDNA|Blotting, Northern|*Telencephalon|3' UTR|Amino Acid Sequence|Base Sequence|RNA, Messenger|Cloning, Molecular|In Situ Hybridization|*Cytoplasm|*Cells, Cultured|Open Reading Frame 26 GPR26 11574155 Gene 2001 10.1016/s0378-1119(01)00651-5 45 0 1 71 Humans|Rats|Male|Animals|Mice|GPR17 protein, human|G-Protein-Coupled Receptors|Receptors, Cell Surface|Cloning, Molecular|GTP-Binding Proteins|Amino Acid Sequence|DNA, Complementary|Chromosome Mapping|Gene Expression|Ligands|mRNA|Tissue Distributions|Pseudogene|Sequence Homology, Amino Acid|Brain|GPR17 protein, mouse|Nerve Tissue Proteins|Gpr26 protein, rat 20 HMG20B 11207365 Cell 2001 10.1016/s0092-8674(01)00209-4 35 5 0 74 Humans|Mice|Animals|BRCA2 protein, human|*BRCA2 Protein|*Genes, BRCA2|DNA-Binding Proteins|Transcription Factors|*Cell Division|Neoplasm Proteins|Amino Acid Sequence|DNA 22 IGIP 11526781 Ginekol. Pol. 2001 0 0 0 16 Infant, Newborn|Pregnancy|Female|Humans|Adult|*Endometriosis|Ovarian Diseases|Infertility, Female|Pregnancy Rate|Fertilization in Vitro|Reproductive Techniques, Assisted|Premature Birth|Cesarean Section|Retrospective Studies|Case-Control Studies|Treatment Outcome 29 IGIP 11526764 Ginekol. Pol. 2001 0 0 0 16 Humans|Female|Pregnancy|*Endometriosis|Episiotomy|External Anal Sphincter|Anus Diseases|Perineum|Scar 29 IGIP 11526763 Ginekol. Pol. 2001 0 0 0 16 Female|Humans|Adult|Catamenial pneumothorax|*Pneumothorax|*Menstruation|Endometriosis|Thoracic Diseases|Danazol|Thoracic Surgery, Video-Assisted|Recurrence 29 IGIP 11526760 Ginekol. Pol. 2001 0 0 0 16 Female|Humans|*Danazol|*Endometriosis|Estrogen Antagonists|Pelvic Pain|*Laparoscopy|*Combined Modality Therapy|*Uterus|*Manipulation, Osteopathic 29 IGIP 11526759 Ginekol. Pol. 2001 0 0 0 16 Humans|Female|*Triptorelin Pamoate|*Endometriosis|Gonadotropin-Releasing Hormone 29 IGIP 11526758 Ginekol. Pol. 2001 0 0 0 16 Female|Humans|*Nafarelin|*Endometriosis|Menstruation|*Thermocoagulation|Pain|Estradiol|Bone Density|Administration, Intranasal 29 IGSF3 11673522 J. Immunol. 2001 10.4049/jimmunol.167.9.5115 26 1 0 44 Humans|Mice|Animals|*Cell Surface Proteins|*Lymphocytes|Tetraspanin 28|Lymphocyte Activation|Membrane Glycoproteins|Tetraspanin 29|Antigens, CD|B-Lymphocytes|Tumor Cells, Cultured|Cell Movement|Base Sequence|CD81 protein, human 20 IGSF3 11504738 J. Biol. Chem. 2001 10.1074/jbc.M107338200 67 4 2 44 Humans|Mice|Animals|Tetraspanin 29|Membrane Glycoproteins|Tetraspanin 28|Membrane Proteins|*Transcription Factors|TSPAN32 protein, human|Tetraspanins|Antigens, CD|Carrier Proteins|Neoplasm Proteins|Protein Binding|Cell Line, Tumor|Amino Acid Sequence|CD81 protein, human 20 KLRC4 11751968 J. Immunol. 2001 10.4049/jimmunol.168.1.240 29 0 1 16 Animals|Humans|*Pan troglodytes|KLRD1 protein, human|*NK Cell Lectin-Like Receptor Subfamily D|Receptors, Natural Killer Cell|NK Cell Lectin-Like Receptor Subfamily C|NK Cell|Lectins, C-Type|NK Cell Lectin-Like Receptor Subfamily K|Membrane Glycoproteins|Antigens, CD|Amino Acid Sequence|Evolution, Molecular 24 PALMD 11707320 Gene 2001 10.1016/s0378-1119(01)00719-3 5 1 0 58 Humans|PALM protein, human|*Membrane Proteins|*Gene Mapping|*Phosphoproteins|Sequence Alignment|Amino Acid Sequence|mRNA|Blotting, Northern|Adaptor Proteins, Signal Transducing|DNA, Complementary|Carrier Proteins|Sequence Homology, Amino Acid|Cloning, Molecular|Exons|*Human Chromosome|Alternative Splicing|Sequence Analysis, DNA|Gene Expression 20 PALMD 11478809 Biochem. Biophys. Res. Commun. 2001 10.1006/bbrc.2001.5329 11 0 0 58 Humans|Mice|Animals|Palmd protein, mouse|*Membrane Proteins|PALM protein, human|*Protein Isoforms|*Cytosol|Amino Acid Sequence|*Phosphoproteins|Sequence Alignment|*RNA Splicing|*Adaptor Proteins, Signal Transducing|Sequence Homology, Amino Acid|Base Sequence|Plasma Membrane|Alternative Splicing|mRNA|Exons|DNA, Complementary|Chromosome Mapping 20 Pl15 11191866 Theriogenology 2001 10.1016/s0093-691x(00)00464-7 0 0 1 0 Humans|Animals|Female|Infant|*Penaeidae|*Electroporation|*DNA|Base Sequence|Southern Blotting|Ovaries|Amino Acid Sequence|Promoter Regions, Genetic|Sequence Analysis, DNA 23 ZNF91 11470777 Int. Immunol. 2001 10.1093/intimm/13.8.1075 2 0 0 55 Humans|Fc gamma receptor IIB|FCGR2B protein, human|*Receptors, IgG|*Transcription Factors|*Promoter Regions, Genetic|Transcription, Genetic|Base Sequence|DNA-Binding Proteins|Binding Sites|Fc Receptors|Electrophoretic Mobility Shift Assay|Antigens, CD|Transfections|Cloning, Molecular|Zinc 26 ZNF91 11410164 DNA Cell Biol. 2001 10.1089/104454901750232472 3 0 0 55 Male|Humans|HEK293 Cells|*Transcription Factors|ZNF350 protein, human|*Repressor Proteins|Zinc Finger Motifs|*Cloning, Molecular|Base Sequence|Nuclear Proteins|cDNA|Amino Acid Sequence|Kruppel-Like Transcription Factors|cDNA Library|Blotting, Northern|Sequence Homology, Amino Acid|Testis 26 ZNF91 11160932 Nucleic Acids Res. 2001 PMC29604 10.1093/nar/29.4.986 4 0 0 55 Humans|Intercalating Agents|Nucleic Acid Conformation|*DNA Replication|DNA|Base Sequence|Oligodeoxyribonucleotides|DNA, Single-Stranded|Thymine|Thermodynamics|TYRP1 protein, human|*Membrane Glycoproteins|*Protein Conformation, beta-Strand|Spectrophotometry, Ultraviolet 26 AP3M2 11080148 EMBO J. 2000 PMC305843 10.1093/emboj/19.22.6011 51 1 1 40 *Adaptor Protein Complex alpha Subunits|*Synaptotagmin|Clathrin|Endocytosis|Adaptor Protein Complex 2|Coated Pits, Cell-Membrane|Adaptor Proteins, Vesicular Transport|Synaptic Vesicles|Membrane Proteins|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 1|Nerve Tissue Proteins|Adaptor Protein Complex 3|Calcium-Binding Proteins|Membrane Glycoproteins|Binding Site|Phosphoproteins|Protein Binding 25 AP3M2 10910768 J. Cell. Sci. 2000 67 1 0 40 Humans|*GTPase|HeLa Cells|*Endocytosis|ral GTP-Binding Proteins|GTPase-Activating Proteins|Signal Transduction|Protein Binding|Adaptor Proteins, Vesicular Transport|Amino Acid Sequence|ATP-Binding Cassette Transporters|EGFR protein, human|Epidermal Growth Factor Receptor 25 AP3M2 10753805 Curr. Opin. Struct. Biol. 2000 10.1016/s0959-440x(00)00071-3 33 8 1 40 Clathrin|*Endocytosis|Coated Pits, Cell-Membrane|Adaptor Protein Complex 2|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 1|Adaptor Protein Complex 3|Clathrin-Coated Vesicles|Adaptor Proteins, Vesicular Transport|Membrane Proteins|Heavy Chain, Clathrin|Protein Binding|Crystallography, Xray|Electron Cryomicroscopy|Binding Sites|clathrin B|*Sesquiterpenes 25 AP3M2 10640811 Cytogenet. Cell Genet. 2000 10.1159/000015391 0 0 0 40 Humans|Mice|Animals|*Adaptors, Clathrin-Associated|*Chromosome Mapping|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 1|Adaptor Protein Complex alpha Subunits|Adaptor Protein Complex 2|Sequences, Amino Acid|Adaptor Protein Complex 3|Membrane Proteins|Base Sequence|Clathrin|Nerve Tissue Proteins|Phosphoproteins|Cloning, Molecular|Sequence Homology, Amino Acid|Genomics|AP1M2 protein, human 25 CDC42EP4 11035016 J. Biol. Chem. 2000 10.1074/jbc.M007039200 38 3 3 127 Mice|Chlorocebus aethiops|Animals|*cdc42 Protein|*Cell Shape|*Fibroblast|Carrier Proteins|Amino Acid Sequence|Signal Transduction|F-Actin|3T3 Cells|Protein Binding|Actin Cytoskeleton|Fibers, Stress|CDH1 protein, human|E Cadherin|COS Cells|Antigens, CD|*Epithelial Cell 20 CDKL2 10800923 J. Neurochem. 2000 10.1046/j.1471-4159.2000.0741809.x 4 0 0 100 Humans|Mice|Animals|Rabbits|*Serine Threonine Kinase|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|*Promoter Regions, Genetic|Exons|Base Sequence|Alternative Splicing|cDNA|Isoforms|Amino Acid Sequence|Transcription, Genetic|Cloning, Molecular|Sequence Homology, Amino Acid|Serine 20 CRYZ 10961608 J. Acquir. Immune Defic. Syndr. 2000 10.1097/00126334-199912150-00007 0 0 0 488 Humans|Guinea Pigs|Animals|*HIV-1|HIV Antibodies|*Immunizations|*Vaccination|Neutralization Tests|*Peptides|HIV Infections|Amino Acid Sequence|Epitopes|*HIV Seropositivity|Peptide Fragments|Tuberculin|Mycobacterium bovis 164 CRYZ 10825607 Vaccine 2000 10.1016/s0264-410x(00)00101-8 5 0 0 488 Adult|Humans|*Salmonella typhi|*Vibrio cholerae|Ty21a typhoid vaccine|*Typhoid-Paratyphoid Vaccines|Cholera Vaccines|*Immunization|*Antibodies, Bacterial|*Vaccination|*Polysaccharides, Bacterial|Cholera|Bacterial Vaccines|Cholera Toxin|Immunoglobulin A|Lipopolysaccharides|Administration, Oral 164 CRYZ 10812736 Bull. World Health Organ. 2000 PMC2560702 6 1 0 488 Infant|Humans|Female|Pregnancy|*Haemophilus influenzae type b|*Tetanus Toxin|Haemophilus influenzae-type b polysaccharide-Neisseria meningitidis outer membrane protein conjugate vaccine|Haemophilus Vaccines|Vaccine, Diphtheria-Tetanus-Pertussis|*Vaccines, Conjugate|*Polysaccharides, Bacterial|polyribose phosphate|*Pentosephosphates|Vaccines, Combined|Tetanus|Bacterial Capsules|Haemophilus Infections|Immunization, Secondary|Antibodies, Bacterial|Pertussis Vaccine|Bacterial Outer Membrane Proteins|Vaccination 164 CRYZ 10738097 Vaccine 2000 10.1016/s0264-410x(00)00006-2 52 0 0 488 cholera vaccine CVD 103-HgR|*Cholera|Double-Blind Method|Indonesia|*Cholera Vaccines|Vibrio cholerae O1|Antibodies, Bacterial|Administration, Oral|Vaccines, Attenuated|Vaccination 164 CRYZ 10720540 J. Infect. Dis. 2000 10.1086/315337 16 0 0 488 Humans|Young Adult|Aged|heat-labile enterotoxin, E coli|*Influenza Vaccines|*Virosomes|*Enterotoxins|*Bacterial Toxins|*Escherichia coli Proteins|*Vaccines, Inactivated|*Adjuvants, Immunologic|*Administration, Intranasal|Influenza, Human|*Adjuvants, Pharmaceutic|Antibodies, Viral|Escherichia coli|Immunoglobulin A|Beijing 164 DGCR2 10633131 J. Med. Genet. 2000 PMC1734454 10.1136/jmg.37.1.33 17 1 2 182 Humans|*DiGeorge Syndrome|Barakat syndrome|*Hypoparathyroidism|Shprintzen Golberg craniosynostosis|*Arachnodactyly|10p Deletion Syndrome (Partial)|Chromosome Deletion|Nephrosis|*Marfan Syndrome|*Craniosynostoses|Chromosome Disorders|Hearing Loss, Sensorineural|Gene Deletion|Haploinsufficiency|Allanson Pantzar McLeod syndrome|*Urogenital Abnormalities|Chromosomes, Human, Pair 10|*Kidney Tubules, Proximal 22 glycosis 10810198 Rev Pneumol Clin 2000 0 0 0 0 Humans|Tomography, X-Ray Computed|Neoplasm Recurrence, Local|*Lung Cancer|*Positron Emission Tomography|Carcinoma, Non-Small-Cell Lung|Fluorodeoxyglucose F18|Radiopharmaceuticals|Solitary Pulmonary Nodule|Mediastinum|Small Cell Lung Carcinoma 21 GPR26 10684976 Biochim. Biophys. Acta 2000 10.1016/s0167-4781(99)00241-9 7 1 0 71 Animals|Humans|Rats|HEK293 Cells|*Receptors, G-Protein-Coupled|Receptors, Cell Surface|Cloning, Molecular|cDNA|GTP-Binding Proteins|Base Sequence|Amino Acid Sequence|PCR|Chromosome Mapping|Gene Library|Genomic Library|Receptors, Serotonin|DNA|Open Reading Frame|Ligands|Transfections|Sequence Homology, Amino Acid 20 HTATSF1 10964778 Virology 2000 10.1006/viro.2000.0480 7 2 0 139 Humans|Animals|Horses|*Positive Transcriptional Elongation Factor B|*HIV-1|*Infectious Anemia Virus, Equine|HeLa Cells|Human Immunodeficiency Virus Long Terminal Repeat|Cyclin T1|CDK9 protein, human|Cyclin-Dependent Kinase 9|tat Gene Products, Human Immunodeficiency Virus|Transcription, Genetic|RNA Polymerase II|Cyclin-Dependent Kinases|Protein-Serine-Threonine Kinases|Gene Expression Regulation, Viral|Cyclins|Transcriptional Activation 26 IGIP 10842794 Schriftenr Ver Wasser Boden Lufthyg 2000 0 0 0 16 *Water Resources|Ghana|Sanitation|Water Supply|Hygiene|Organizations|Toilet Facilities|Public Health|Developing Countries|Health Education|Government|Conservation of Natural Resources|Germany 29 KLRC4 10783260 Genomics 2000 10.1006/geno.2000.6163 8 0 0 16 Humans|KLRD1 protein, human|NK Cell Lectin-Like Receptor Subfamily D|*Chromosome Mapping|KLRB1 protein, human|NK Cell Lectin-Like Receptor Subfamily B|Killer Cell Lectin-Like Receptors|Lectins, C-Type|Natural Killer Cells|Antigens, CD|Sequence Tagged Site|*Chromosome 2|Membrane Glycoproteins|Expressed Sequence Tags|Multigene Family|OLR1 protein, human|Scavenger Receptors, Class E 24 PDE3B signalling 10677351 Biochem. J. 2000 PMC1220858 10.1042/bj3460337 21 0 0 0 Animals|Mice|*3T3-L1 Cells|*Tumor Necrosis Factor-alpha|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Down-Regulation|*Adipocytes|Lipolysis|3',5'-Cyclic-AMP Phosphodiesterases|Protein Kinase A|Cyclic AMP|Cell Differentiation|Phosphorylation|Insulin Resistance|Insulin 21 STOML1 10713127 J. Biol. Chem. 2000 10.1074/jbc.275.11.8062 28 0 1 71 Animals|Humans|Integral Membrane Proteins|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Blood Proteins|Amino Acid Sequence|Erythrocyte Membrane|Helminth Proteins|Base Sequence|Anemia, Hemolytic, Congenital|*Erythrocytes|Sequence Homology, Amino Acid|Western Blots|DNA, Complementary|Cloning, Molecular|mRNA|Electrophoresis, Polyacrylamide Gel|Ion Channel 20 ZNF91 10993601 DNA Seq. 2000 10.3109/10425179809034075 8 0 0 55 Animals|*Zinc Finger|*Mammals|Gene Clusters|Transcription Factors|Sequence Alignment|Evolution, Molecular|Repressor Proteins|Kruppel-Like Transcription Factors|Amino Acid Sequence|Phylogeny|Genomes|Zinc 26 AP3M2 10589826 Mol. Gen. Genet. 1999 10.1007/s004380051099 22 0 2 40 Animals|*Adaptor Protein Complex 3|*Drosophila|*Carmine|Drosophila melanogaster|Adaptor Protein Complex 1|Adaptor Protein Complex alpha Subunits|Adaptor Protein Complex mu Subunits|Integral Membrane Proteins|Adaptor Protein Complex 2|Adaptor Proteins, Vesicular Transport|Monomeric Clathrin Assembly Proteins|*Pigmentation|Nerve Tissue Proteins|Phosphoproteins|Amino Acid Sequence|Sequence Homology, Amino Acid 25 AP3M2 10228163 EMBO J. 1999 PMC1171331 10.1093/emboj/18.9.2489 78 1 1 40 *Clathrin|Clathrin Adaptor Protein Complex 2|*Endocytosis|Coated Pits, Cell-Membrane|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 1|*Protein Binding|Adaptor Protein Complex 3|Membrane Proteins|Adaptor Protein Complex alpha Subunits|Adaptor Proteins, Vesicular Transport|CD71 antigen|Transferrin Receptor|*Adaptor Proteins, Signal Transducing|Membrane Glycoproteins|Binding Sites|EGFR protein, human|Epidermal Growth Factor Receptor 25 AP3M2 10050758 FEBS Lett. 1999 10.1016/s0014-5793(99)00066-6 1 19 0 40 *Clathrin-Coated Vesicles|*Tyrosine|*Phosphorylation|Adaptor Protein Complex 2|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 1|Adaptor Protein Complex 3|Clathrin|Adaptor Proteins, Vesicular Transport|Adaptor Protein Complex alpha Subunits|Membrane Proteins|Nerve Tissue Proteins|Endocytosis|Phosphoproteins|Membrane Glycoproteins|Plasma Membrane|Protein Binding|Binding Sites 25 ATL2 10480382 Plant Mol. Biol. 1999 10.1023/a:1006267201855 0 1 0 95 *Arabidopsis|Arabidopsis Proteins|*Multigene Family|Gene Expression Regulation, Plant|Genes, Plant|Plants, Genetically Modified|Promoter Regions, Genetic|Zinc Fingers|Plant Proteins|Sequence Homology, Amino Acid|DNA, Plant|Amino Acid Sequence|Base Sequence|Sequence Alignment|DNA, Complementary|ATL2 protein, Arabidopsis|DNA-Binding Proteins 23 CDC42EP4 10490598 Mol. Cell. Biol. 1999 PMC84628 10.1128/mcb.19.10.6585 41 17 4 127 Chlorocebus aethiops|Mice|Animals|rho GTPases|cdc42 GTP-Binding Protein|RHOA protein, human|rhoA GTP-Binding Protein|Signal Transduction|Amino Acid Sequence|Cell Cycle Proteins|rac GTP-Binding Proteins|Mitogen-Activated Protein Kinases|Protein Binding|COS Cells|3T3 Cells|Sequence Homology, Amino Acid 20 CDC42EP4 10430899 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17736 10.1073/pnas.96.16.9083 12 3 1 127 Mice|Chlorocebus aethiops|Animals|*cdc42 Protein|Cell Cycle Proteins|*Fibroblasts|Signal Transduction|GTP-Binding Proteins|rac GTP-Binding Proteins|Amino Acid Sequence|Protein Binding|Actin|p21-Activated Kinases|COS-7 Cells|Binding Sites|3T3 Cells 20 CDKL2 10531455 J. Neurosci. 1999 PMC6782914 16 0 0 100 Animals|Rabbits|CDKL2 protein, human|*CDC2 Protein Kinase|*Cyclin-Dependent Kinase 2|*Calcium-Calmodulin-Dependent Protein Kinases|*Learning|Conditioning, Classical|Cerebellar Nucleus|*Myosin-Light-Chain Kinase|Blinking|Memory|Cerebellum|Amino Acid Sequence|Gene Library|cDNA 20 CES1P1 10452915 Placenta 1999 10.1053/plac.1999.0407 12 0 0 5 Female|Pregnancy|Animals|Humans|CES2 protein, human|*Carboxylesterase B|Carboxylesterases|*Cloning, Molecular|Amino Acid Sequence|Base Sequence|cDNA|Microsomes, Liver|Northern Blotting|Liver|Hydrolysis|*Placenta|Mammals|Xenobiotics 20 IGIP 10462966 Ginekol. Pol. 1999 0 0 0 16 Humans|Adolescent|Female|Uterine Anomalies|*Uterus|*Urogenital Abnormalities|Pelvic Pain 29 IGIP 10462960 Ginekol. Pol. 1999 0 0 0 16 Humans|Female|Adolescent|*Pelvic Pain|Endometriosis|Dysmenorrhea|*Laparoscopy|Contraceptives, Oral, Combined|Anti-Inflammatory Agents, Non-Steroidal|Contraception|Fertility|1-methyl-4-(1-naphthylvinyl)piperidine|Piperidines|Research Design 29 PARM1 10499539 Endocrinology 1999 10.1210/endo.140.10.7097 6 3 0 49 Male|Humans|Rats|Mice|Animals|*Prostate|*Androgens|Orchiectomy|*Apoptosis|Messenger RNA|Gene Expression|Complementary DNA|Estrogens|In Situ Hybridization 20 PDE3B signalling 10417351 Biochem. J. 1999 PMC1220425 21 5 0 0 Rats|Animals|*Phosphorylation|*Protein Phosphatase 2A|Pde3b protein, rat|*Phosphodiesterase 3B|*Adipocytes|3',5'-Cyclic-AMP Phosphodiesterases|Okadaic Acid|*Enzyme Inhibitors|Insulin|Proto-Oncogene Proteins c-akt|tautomycin|Pyrans|Signal Transduction|calyculin A|Oxazoles|Spiro Compounds|Isoproterenol|Serine 21 PDE3B signalling 10191258 Biochem. J. 1999 PMC1220156 3 15 0 0 Rats|Animals|*Insulin|*Lipolysis|peroxovanadate|*Vanadates|Phosphatidylinositol 3-Kinases|INSR protein, human|Insulin Receptor|*Adipocytes|*Insulin, Regular, Human|Phosphorylation|Insulin Receptor Substrate 1|Isoprenaline|Glucose|Tyrosine|Phosphoproteins|Antigens, CD 21 POTEE 10495733 Acad Med 1999 10.1097/00001888-199908000-00017 11 0 0 39 Female|Humans|Retrospective Studies|*Physicians, Women|*Medicine|Parental Leave|Career Choice|Specialization|Attitude of Health Personnel|Surveys and Questionnaires 20 STOML1 9931417 Gene 1999 10.1016/s0378-1119(98)00532-0 13 0 0 71 Animals|Humans|*Caenorhabditis elegans|Caenorhabditis elegans Proteins|*Cloning, Molecular|Amino Acid Sequence|cDNA|Exon|Base Sequence|Helminth Proteins|Intron|Sequence Alignment|Northern Blot|Splicings, Alternative|Sequence Homology, Amino Acid|Membrane Proteins|RNA, Messenger|Sequence Analysis, DNA|*Brain|MEC-2 protein, C elegans 20 ZNF91 10360839 DNA Cell Biol. 1999 10.1089/104454999315277 17 0 1 55 Humans|Male|Mice|Animals|*Rodents|*Zinc Finger|Transcription Factors|Amino Acid Sequence|Repressor Proteins|Base Sequence|Kruppel-Like Transcription Factors|Gene Expression|Sequence Homology, Amino Acid|Genome, Human 26 ZNF91 10335408 Bioorg. Khim. 1999 0 0 0 55 Humans|*Endogenous Retroviruses|*Introns|*Long Terminal Repeat|Cloning, Molecular|Restriction Mapping|Sequence Homology, Nucleic Acid|Transcription, Genetic|DNA, Viral 26 AP3M2 9812899 Science 1998 PMC5600252 10.1126/science.282.5392.1327 208 4 3 40 *Tyrosine|Adaptor Protein Complex mu Subunits|*Endocytosis|Adaptor Protein Complex 2|Adaptor Protein Complex 1|Adaptor Protein Complex 3|Cell Surface Proteins|Adaptor Protein Complex alpha Subunits|Clathrin|Adaptor Proteins, Vesicular Transport|Nerve Tissue Proteins|Signal Peptides|Membrane Glycoproteins|Phosphoproteins|Protein Binding|Amino Acid Sequence|Binding Sites|Molecular Conformation 25 AP3M2 9774424 J. Biol. Chem. 1998 10.1074/jbc.273.43.28073 8 3 1 40 *Tyrosine|tyrphostin A23|*Tyrphostins|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 2|Adaptor Protein Complex 1|Integral Membrane Proteins|Adaptor Protein Complex 3|*Clathrin-Coated Vesicles|Clathrin|Adaptor Protein Complex alpha Subunits|Adaptor Proteins, Vesicular Transport|Endocytosis|Membrane Glycoproteins|Plasma Membrane|Nerve Tissue Proteins|Binding Sites|Phosphoproteins 25 AP3M2 9398332 Biochemistry 1998 10.1021/bi971762i 28 5 0 40 CTLA4 protein, human|*CTLA-4 Antigen|*Clathrin|*Phosphorylation|Adaptor Protein Complex 2|Adaptor Protein Complex mu Subunits|CD28 Antigens|Adaptor Proteins, Vesicular Transport|Abatacept|Antigens, CD|T-Lymphocytes|Lymphocyte Activation|Signal Transduction|Amino Acid Sequence|Phosphoproteins|Membrane Proteins|Nerve Tissue Proteins|Tyrosine Kinase 25 CDKL2 9721213 Genomics 1998 10.1006/geno.1998.5391 30 0 2 100 Humans|Animals|Mice|Base Sequence|Amino Acid Sequence|Sequence Alignment|cDNA|Chromosome Mapping|Cloning, Molecular|Proteins|Serine Threonine Kinases|Exons|Sequence Homology, Amino Acid|Nance-Horan syndrome|Genetic Diseases, X-Linked|*Chromosome Structures|Phosphorylation|Cataract|Tooth Abnormalities 20 IGSF3 9790749 Genomics 1998 10.1006/geno.1998.5439 3 0 0 44 Humans|*DNA, Complementary|*Membrane Protein|*Cloning, Molecular|*Chromosome Banding|Sequence Alignment|Amino Acid Sequence|Chromosome Mapping|Base Sequence|mRNA|*Immunoglobulin|Blotting, Northern|Sequence Homology, Amino Acid|In Situ Hybridization, Fluorescence|Sequence Analysis, DNA|*Chromosome Structures|*Membrane 20 Resp18 9609992 J. Hum. Genet. 1998 10.1007/s100380050030 1 0 0 423 Humans|Animals|Rabbits|*Hyperplasia|Tunica Intima|Muscle, Smooth, Vascular|Carotid Artery Injuries|Aorta|Gene Expression|*Gene Expression Profiling 23 Resp18 9415067 J. Endocrinol. 1998 10.1677/joe.0.1550329 1 0 0 423 Female|Animals|Rats|regulated endocrine secretory protein 18|*Nerve Tissue Proteins|Pituitary Gland|In Situ Hybridization|mRNA|Neuropeptide Y|Blotting, Western|Pancreatic Islets|Immunocytochemistry|Somatostatin|Neurosecretory Systems|Thyroid Gland 23 ZNF91 9839802 DNA Cell Biol. 1998 10.1089/dna.1998.17.931 7 0 0 55 Humans|Male|Adult|*Zinc Finger|Transcription Factors|Nuclear Proteins|Repressor Proteins|Base Sequence|Amino Acid Sequence|Kruppel-Like Transcription Factors|DNA|Cloning, Molecular|Sequence Homology, Amino Acid|BRAF protein, human|*Proto-Oncogene Proteins B-raf|Testis|Cell Line 26 Pl15 8995537 Life Sci. 1997 10.1016/s0024-3205(96)00593-0 21 0 1 0 Animals|Rats|nociceptin|*Diuretic|*Rats, Sprague-Dawley|*Opioid Peptides|Diuresis|Receptors, Opioid|Blood Pressure|Heart Rate|Kidney|Injections, Intraventricular|Narcotic Antagonists|Brain|Central Nervous System 23 Resp18 9369452 Mol. Endocrinol. 1997 10.1210/mend.11.12.0024 4 0 0 423 Rats|Animals|regulated endocrine secretory protein 18|Nerve Tissue Proteins|Pituitary Gland|*Neurosecretory Systems|Amino Acid Sequence|Base Sequence|Northern Blotting|RNA, Messenger|*Signal Transduction|Tissue Distribution|Endoplasmic Reticulum|Up-Regulation|Limk2 protein, rat|Lim Kinases 23 Resp18 9283614 J. Histochem. Cytochem. 1997 10.1177/002215549704500910 0 0 0 423 Rats|Animals|regulated endocrine secretory protein 18|*Nerve Tissue Proteins|Paraventricular Nucleus|AVP protein, human|Vasopressin|Arcuate Nucleus|Corticotropin-Releasing Hormone|*Neurons|Neuropeptide Y|Thyrotropin-Releasing Hormone|Oxytocin|Hypothalamus|Rats, Sprague-Dawley|mRNA|In Situ Hybridization|Reticular Formation|Brainstem|Neurophysins 23 CDKL2 9000130 Oncogene 1996 13 3 0 100 Humans|Male|Female|*Epidermal Growth Factor|CDKL2 protein, human|*Calcium-Calmodulin-Dependent Protein Kinases|Mitogen-Activated Protein Kinases|Phosphorylation|*Cloning, Molecular|Mitogen-Activated Protein Kinase Kinases|Protein-Tyrosine Kinases|Mitogen-Activated Protein Kinase 1|Signal Transduction|Mitogen-Activated Protein Kinase 3|Enzyme Activation|Amino Acid Sequence|Base Sequence|Protein Kinase A 20 fibronogen 8853385 Am. J. Physiol. 1996 10.1152/ajpregu.1996.271.3.R634 3 3 0 0 Animals|Hyperthermia, Induced|*Heat Shock|*Reperfusion|*Ischemia|Liver|Reperfusion Injury|HSP72 Heat-Shock Proteins|Gene Expression|*Liver Diseases|RNA, Messenger 23 fibronogen 8871914 Med Sci Sports Exerc 1996 10.1097/00005768-199608000-00014 4 0 0 0 Humans|Male|*Endurance Training|*Human Body|Body Water|*Indicator Dilution Techniques|Physical Endurance|Plasma Volume|Body Fluids|Radioisotope Dilution Technique|Electric Impedance|Intracellular Fluid|Blood Volume|*Radioisotopes 23 fibronogen 8841845 Int J Artif Organs 1996 1 0 0 0 Humans|Logiparin|*Heparin, Low-Molecular-Weight|Heparin|*Cross-Over Studies|*Renal Dialysis|Activated Partial Thromboplastin Time|Anticoagulants|Blood Coagulation|Kidney Failure, Chronic|Thrombus|Factor Xa Inhibitors 23 fibronogen 8756816 Am. J. Respir. Crit. Care Med. 1996 10.1164/ajrccm.154.2.8756816 2 1 0 0 *Bradykinin|Bronchial Provocation Tests|Airway Resistance|Methacholine Chloride|Asthma|Lung|Bronchoscopy|Bronchoalveolar Lavage Fluid|Bronchoalveolar Lavage 23 MTX3 9119095 Eur. J. Obstet. Gynecol. Reprod. Biol. 1996 10.1016/s0301-2115(95)02589-8 7 0 0 133 Pregnancy|Humans|Female|*Pregnancy, Interstitial|Methotrexate|Fallopian Tubes|Chorionic Gonadotropin|Laparoscopy 21 MTX3 8787415 Appl. Environ. Microbiol. 1996 PMC167996 10 0 0 133 Animals|*Bacillus|Bacterial Toxins|Cloning, Molecular|Genes, Bacterial|Clostridium perfringens|DNA, Bacterial|Mosquito|Pest Control, Biological|Bacterial Proteins|Escherichia coli 21 ncln 8766532 Jpn. J. Cancer Res. 1996 PMC5921140 10.1111/j.1349-7006.1996.tb00274.x 1 0 0 65 Male|Mice|Animals|*Mice, Inbred C3H|*Radiotherapy Dosage|BALB C Mice|Cell Division|Neoplasms, Experimental|*Radiation Dosage|*Tumors|Cell Survival|Cell Count|*Cell Proliferation 21 Pl15 8684261 Life Sci. 1996 10.1016/0024-3205(96)00260-3 14 0 2 0 Animals|Rabbits|*Resveratrol|*Atherosclerosis|Hypercholesterolemia|lipoprotein cholesterol|Cholesterol|Cholesterol, Dietary|Lipoproteins|oxidized low density lipoprotein|Lipoproteins, LDL|Hyperlipidemias|Stilbenes 23 Resp18 8985141 J. Histochem. Cytochem. 1996 10.1177/44.12.8985141 1 0 0 423 Animals|Rats|Male|*Testis|regulated endocrine secretory protein 18|*Nerve Tissue Proteins|Sertoli Cells|Spermatozoa|Spermatogenesis|*Inferior Colliculi|mRNA|In Situ Hybridization|Spermatids|Pro-Opio-Melanocortin|Northern Blots|Immunohistochemistry|Spermatocytes|Western Blots 23 Resp18 9053801 Neuroscience 1996 10.1016/0306-4522(95)00458-0 0 0 0 423 Animals|Rats|regulated endocrine secretory protein 18|*Diencephalon|*Nerve Tissue Proteins|Hypothalamus|*Neurons|Thalamus|Amygdala|Preoptic Areas, Lateral|Hippocampus|Paraventricular Nucleus|Dorsomedial Nucleus|Suprachiasmatic Nucleus|Anterior Hypothalamic Area|Neurosecretory Systems 23 CPA6 7809097 Proc. Natl. Acad. Sci. U.S.A. 1994 PMC45499 10.1073/pnas.91.26.12664 10 6 0 44 Mice|Animals|bombesin nonapeptide|*Bombesin|Iodine-125|*Iodine Radioisotopes|Gastrin Releasing Peptide|Receptors, Bombesin|Peptide Fragments|Amino Acid Sequence|*Antineoplastic Agents|Structure-Activity Relationship|3T3 Cells|Fibroblast|Pancreas 24 fibronogen 8011139 Zhongguo Zhong Yao Za Zhi 1994 0 0 0 0 Rats|Animals|*Aconitum|*Hemorrheology|Blood Viscosity|Erythrocyte Aggregation|Platelet Aggregation|Rats, Sprague-Dawley|Drugs, Chinese Herbal|*Disease Models, Animal|Fibrinogen|*Syndrome 23 fibronogen 8446931 Thromb. Haemost. 1993 2 0 0 0 Humans|*Asparaginase|*Escherichia coli|*Acute Lymphoblastic Leukemia|SERPINC1 protein, human|Antithrombin III|antithrombin III-protease complex|Blood Coagulation Disorders|*Hypercoagulability|Thrombosis|Protein S|Factor VII|alpha-2-Antiplasmin|Anticoagulants|Antineoplastic Combined Chemotherapy Protocols|Peptide Hydrolases 23 fibronogen 8061244 Biomed. Pharmacother. 1993 10.1016/0753-3322(93)90341-h 0 0 0 0 Humans|SERPINE1 protein, human|Plasminogen Activator Inhibitor 1|*Atherosclerosis|Fibrinogen|Myocardial Infarction|Lupus Anticoagulant|Thrombosis|Antibodies, Anticardiolipin|Myocardial Ischemia|Hemostasis|*Plasma|Lipoprotein(a) 23 CDC42EP4 1629197 J. Biol. Chem. 1992 9 0 0 127 Humans|*DNA, Complementary|*Bone Marrow|*Bone Marrow Stromal Cell|Blotting, Northern|CDC42EP1 protein, human|*Adaptor Proteins, Signal Transducing|Cloning, Molecular|Base Sequence|Amino Acid Sequence|RNA, Messenger|Restriction Mapping|DNA|Nucleic Acid Hybridization|Blotting, Southern|Recombinant Proteins|Open Reading Frame|Endothelial Cell 20 glycosis 1531010 Biochem. J. 1992 PMC1130672 10.1042/bj2810267 20 1 1 0 Rats|Animals|imidazolecarboxamide|*Glycolysis|AICA ribonucleotide|*Aminoimidazole Carboxamide|acadesine|Ribonucleotides|Ribonucleosides|Gluconeogenesis|*Hepatocytes|Liver|Glucose|fructose-6-phosphate|Fructosephosphates|6-Phosphofructo-2-kinase|Glucose-6-Phosphate|Nucleotides|Lactate|Fructose 21 fibronogen 1759983 Atherosclerosis 1991 10.1016/0021-9150(91)90105-c 0 0 0 0 Humans|*Risk Factors|*Hemostasis|Fibrinogen|Blood Coagulation Factors|*Disease, Vascular|SERPINC1 protein, human|Antithrombin III|Factor VII|Protein C|von Willebrand Factor|Myocardial Infarction|HDL Cholesterol|Triglycerides|Lipids|Ischemia|Hemostatics 23 fibronogen 1786243 J Biomater Sci Polym Ed 1991 10.1163/156856292x00079 2 0 0 0 *Adsorption|*Fibrinogen|Iodine-125|*Iodine Radioisotopes|biomer|Polyurethanes|hydroxyethyl methacrylate|Methacrylates|*Blood Plasma|*Enzyme-Linked Immunosorbent Assay|hydroxyethyl methacrylate-ethyl methacrylate|Polyhydroxyethyl Methacrylate|Biocompatible Materials|Surface Properties|poly(ethylmethacrylate)|Methylmethacrylates|*Hemostatics|Antibodies 23 glycosis 1816969 Dtsch Z Mund Kiefer Gesichtschir 1991 0 0 0 0 Humans|GPI protein, human|*Glucose-6-Phosphate Isomerase|Cancer, Tongue|Mouth Neoplasms|Carcinoma, Squamous Cell|Radiotherapy Dosage|Mouth Floor|*Tongue|Lymphatic Metastasis|*Cytokines|*Tongue Diseases 21 fibronogen 2486349 Hell Stomatol Chron 1989 0 0 0 0 Fibrin Adhesive|Factor XIII|Tissue Adhesives|Thrombin|Wound Healing|Fibrinogen|Fibrin|Blood Coagulation|Aprotinin|Fibrinolysis|Hemostasis|Skin|*Maxillofacial Surgery 23 MTX3 2904427 Jpn. J. Cancer Res. 1988 PMC5917634 10.1111/j.1349-7006.1988.tb01533.x 9 0 0 133 Mice|Humans|Female|Animals|*Adriamycin|*Tissue Distribution|Cell Line, Tumor|Endothelial Cells|Ovarian Cancer|*Antibodies, Monoclonal|ATP Binding Cassette Transporter, Subfamily B, Member 1|Leukemia|*B Cells|Neoplasm Proteins|Immunocytochemistry|Antineoplastic Agents|Membrane Glycoproteins|Drug Resistance|Flow Cytometry 21 glycosis 3449024 Arq Neuropsiquiatr 1987 10.1590/s0004-282x1987000400008 0 0 0 0 Humans|*Acquired Immunodeficiency Syndrome|Cryptococcosis|Toxoplasmosis|Opportunistic Infections|Nervous System Diseases|Antigens, Fungal|Cysticercosis|Syphilis 21 PARM1 3082610 DNA 1986 10.1089/dna.1986.5.1 3 2 0 49 Rats|Animals|*NADPH-Ferrihemoprotein Reductase|*DNA, Complementary|*Saccharomyces cerevisiae|*NADP|POR protein, human|*Cytochrome P-450 Enzyme System|Plasmids|Cloning, Molecular|DNA|Sequences, Amino Acid|Alcohol Dehydrogenase I|Hemeproteins|RNA, Messenger|7-ethoxycoumarin|Coumarins 20 fibronogen 3987135 Clin Obstet Gynecol 1985 10.1097/00003081-198528010-00009 0 0 0 0 23 glycolisis 6937153 An. Esp. Pediatr. 1980 0 0 0 0 *Disease, Glycogen Storage|*Amylo-1,6-Glucosidase Deficiency|Glycogen|Liver|Hypoglycemia|Blood Glucose|Glucagon|Glucosidases 23 glycolisis 7468250 Acta Physiol Acad Sci Hung 1980 0 1 0 0 Rats|Animals|*Calcium|Myocardium|Heart|Myocardial Contraction|Oxygen Consumption|Coronary Circulation|Heart Ventricles|Glucose|NAD|Perfusion|Pyruvates|Oxygen|Redox|Lactate 23 glycosis 40341 Vox Sang. 1979 10.1111/j.1423-0410.1979.tb02296.x 0 0 0 0 *2,3-Diphosphoglycerate|*Erythrocytes|Hemoglobin|Oxygen|Diphosphoglyceric Acids|Hydrogen-Ion Concentration|Glycolysis|Phosphates 21 fibronogen 757901 Med J Zambia 1978 0 0 0 0 Humans|*Fibrinogen|Zambia|*Venous Thrombosis|Iodine-125|*Iodine Radioisotopes|Pulmonary Embolism|Thrombophlebitis|Radionuclide Imaging|Phlebography|*Hemostatics|Postoperative Complications 23 fibronogen 638434 Br J Surg 1978 10.1002/bjs.1800650317 0 0 0 0 Humans|*Fibrinogen|*Insulin|*Glucose|*Femoral Artery|Arteries, Popliteal|Arterial Occlusive Diseases|*Insulin, Regular, Human|Vascular Patency|*Hemostatics|Lipids 23 glycolisis 753634 Eur. Neurol. 1978 10.1159/000114985 0 0 0 0 Animals|Humans|Male|*Brain Ischemia|*Cerebral Infarction|Ischemic Attack, Transient|Brain|Cerebrovascular Disorders|Cerebrovascular Circulation|Oxygen Consumption|Glucose|*Cardiovascular System|*Animals, Laboratory|Oxygen 23 fibronogen 339885 Arch Orthop Unfallchir 1977 10.1007/BF00415894 1 0 0 0 Humans|*Fibrin Tissue Adhesive|*Bone Transplantation|Factor XIII|Thrombin|Tissue Adhesives|Fibrinogen|Wound Healing|Hemostasis|*Bone, Cancellous|Drug Combinations|*Transplants|Bone 23 glycosis 198951 Vopr Onkol 1977 0 0 0 0 Animals|*Carcinoma, Hepatocellular|*Oxidative Phosphorylation|*Liver Neoplasms|Glycolysis|Carcinoma, Ehrlich Tumor|RNA, Neoplasm|Adenosine Triphosphate|Oxygen Consumption|Ascites|Uridine|*Biochemical Phenomena|RNA 21 glycosis 1182148 Biochim. Biophys. Acta 1975 10.1016/0005-2736(75)90244-8 4 0 0 0 Humans|*Erythrocyte Membrane|*Phospholipids|phosphatidylethanolamine|Phosphatidylethanolamines|Membrane Lipids|Erythrocytes|*Glycolysis|Hexanols|Glucose 21 glycosis 1155608 Am. J. Physiol. 1975 10.1152/ajplegacy.1975.228.6.1787 16 0 0 0 Animals|Rats|*Gluconeogenesis|*Glycolysis|Phosphoenolpyruvate Carboxykinase (GTP)|Pyruvate Kinase|Phosphoenolpyruvate Carboxykinase (ATP)|Liver|Ventromedial Hypothalamic Nucleus 21 glycosis 127407 Strahlentherapie 1975 1 0 0 0 Guinea Pigs|Animals|*Glycolysis|Phosphofructokinase-1|6 Phosphogluconate Dehydrogenase|Hexokinase|*Myocardium|Shunt, Pentosephosphate|Pyruvate Kinase|Glucosephosphate Dehydrogenase|glucose-1-phosphate|Glucosephosphates|Pyruvates|Glycogen|Glucose-6-Phosphate|alpha-glycerophosphoric acid|Glycerophosphates|Adenosine Triphosphate|Glucose|*Electrolytes 21 glycosis 1239860 Vopr Onkol 1975 0 0 0 0 Rats|Animals|dimazine|*Intestine|Intestine, Large|1,2-Dimethylhydrazine|*Neoplasms, Experimental|Intestine, Small|Colonic Neoplasms|Intestinal Mucosa|Adenocarcinoma|Carcinogens|Hexokinase 21 ABCDE 32636280 BMJ Open 2020 PMC7342483 10.1136/bmjopen-2019-032023 0 0 0 0 *Follow-Up Studies|*Simulation Training|Internship and Residency|Clinical Competence|*Hospitals, University|Learning 377 ABCDE 32582231 Front Plant Sci 2020 PMC7296989 10.3389/fpls.2020.00609 0 0 0 0 Jatropha|Biofuels|Seeds|Gene Expression Regulation, Plant|Plant Oils|Gene Expression Profiling|Fossil Fuels 377 ABCDE 32507969 Radiologe 2020 10.1007/s00117-020-00704-3 0 0 0 0 Humans|Polytrauma|Resuscitation|Emergency Service, Hospital 377 ABCDE 32433185 Simul Healthc 2020 10.1097/SIH.0000000000000462 0 0 0 0 Humans|*Task Performance and Analysis|Teams, Healthcare|Simulation Training|Clinical Competence|*Intensive Care|Leadership 377 ABCDE 32414557 Intensive Crit Care Nurs 2020 10.1016/j.iccn.2020.102873 0 0 0 0 Adult|Humans|*Critical Illness|*Respiration, Artificial|Intensive Care Units|Critical Care|Delirium|Patient Care Bundles|Pain Management|Analgesia|Pain|3'-(1-butylphosphoryl)adenosine|Breathing 377 ABCDE 32326948 BMC Med Educ 2020 PMC7181571 10.1186/s12909-020-02030-7 0 0 0 0 Humans|*Virtual Reality|*Learning|Clinical Competence 377 ABCDE 32276739 Curr Probl Cardiol 2020 10.1016/j.cpcardiol.2020.100578 0 0 0 0 Humans|Aged|Carotid Intima-Media Thickness|*Heart Failure|Ankle-Brachial Index|*Ultrasonography|Echocardiography|Carotid Arteries|Coronary Artery Disease|Risk Assessment|Risk Factors|Abdominal Aorta 377 ABCDE 32266730 Pediatr Dermatol 2020 10.1111/pde.14158 0 0 0 0 Humans|*Melanoma|Skin Neoplasms|Self-Examination|Nevus, Pigmented|Nevus|*Students 377 ABCDE 32210513 Acta Inform Med 2020 PMC7085326 10.5455/aim.2020.28.37-41 0 0 0 0 Male|*Cancer, Skin|Dermoscopy|Melanoma|Carcinoma, Squamous Cell|Telemedicine|Physical Examination|Sensitivity and Specificity 377 ABCDE 32193871 J Cancer Educ 2020 10.1007/s13187-020-01735-z 0 0 0 0 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Dermatologists|Dermatology|Family Practice|Practice Patterns, Physicians'|Clinical Competence|Specialists|Questionnaire|Consultations|*Knowledge|Brazil 377 ABCDE 32168511 AACN Adv Crit Care 2020 10.4037/aacnacc2020451 0 0 0 0 Humans|*Critical Care|Intensive Care Units|Mechanical Ventilation|Delirium|*Pain|Critically Ill|Management, Pain|Hypnotics and Sedatives|*Breathing 377 ABCDE 32097117 Perm J 2020 PMC7039420 10.7812/TPP/19.157 0 0 0 0 Humans|*Students, Medical|*Learning|Truth Disclosure|Physician-Patient Relations|Role Playing|Communication|Clinical Competence|Schools, Medical 377 ABCDE 32036487 Int J Cardiovasc Imaging 2020 10.1007/s10554-020-01789-6 0 0 0 0 Male|Humans|*Echocardiography, Stress|Fractional Flow Reserve, Myocardial|Coronary Vessels|*Echocardiography|Coronary Circulation|Coronary Artery Disease|Myocardial Contraction|Myocardial Ischemia|Blood Flow Velocity|Vasodilator Agents|*Dyspnea 377 ABCDE 31938825 Intensive Care Med 2020 PMC7103016 10.1007/s00134-019-05892-8 1 0 0 0 Humans|*Respiratory Muscle|Diaphragm|Critically Ill|Critical Care|*Ultrasonography|Intensive Care Units|Respiration, Artificial|Lungs|*Neuroimaging|Emergency Department|Heart 377 ABCDE 31935204 J Nurs Res 2020 10.1097/jnr.0000000000000326 0 0 0 0 Humans|*Students, Nursing|*Self-Examination|Education, Nursing, Baccalaureate|*Cancer, Skin|Health Knowledge, Attitudes, Practice|Clinical Competence|Surveys and Questionnaires|*Knowledge|Turkey 377 ABCDE 31930512 J Exp Anal Behav 2020 10.1002/jeab.579 0 0 0 0 Adult|Humans|Discrimination Learning|Concept Formation|Generalization, Psychological|Association Learning|Photic Stimulation|Color|Abstracting and Indexing|African Americans|Excipients|Tongue Diseases 377 ABCDE 31928903 Oral Surg Oral Med Oral Pathol Oral Radiol 2020 10.1016/j.oooo.2019.11.014 0 0 0 0 Humans|Truth Disclosure|Physician-Patient Relations|Communication|*Oropharyngeal Cancer 377 ABCDE 31925467 Radiologe 2020 10.1007/s00117-019-00633-w 0 0 0 0 *Polytrauma|*Tomography, X-Ray Computed|*Resuscitation|Injury Severity Score|Emergency Service, Hospital|*Longitudinal Studies 377 ABCDE 31917011 Patient Educ Couns 2020 10.1016/j.pec.2019.12.009 1 0 0 0 Humans|Randomized Controlled Trials as Topic|*Melanoma|*Self-Examination|Skin Neoplasms 377 ADGRV1 32658404 Otol. Neurotol. 2020 10.1097/MAO.0000000000002671 0 0 0 90 Humans|*Cochlear Implants|*Cochlear Implantation|*Hearing Loss|*Deafness|*Audiometries|Cochlea|Auditory Threshold|Hearing|*Cohort Studies 27 ADGRV1 32146541 Mol. Genet. Genomics 2020 10.1007/s00438-020-01657-x 1 0 0 90 Humans|*Whole Exome Sequencing|*Epilepsy|Exome|Genetic Testing|Mutation|Genetic Predisposition to Disease|Sequencing, Next-Generation|Phenotype|Epilepsy, Generalized|Cohort Studies|PCDH19 protein, human|Cadherins|NPRL3 protein, human|GTPase-Activating Proteins 27 ADGRV1 32050993 J Transl Med 2020 PMC7014749 10.1186/s12967-020-02258-3 1 0 0 90 *Retinitis Pigmentosa|*Sequencing, Whole Genome|DNA Mutational Analysis|Pedigree|Genes, Recessive|Genetic Association Studies|High-Throughput Nucleotide Sequencing|Mutation|*Heredity|*Algorithm 27 ADGRV1 32048449 Mol Genet Genomic Med 2020 PMC7196461 10.1002/mgg3.1177 1 0 0 90 Humans|Nonsyndromic Deafness|*Deafness|*Asian Continental Ancestry Group|Hearing Loss, Sensorineural|Connexins|Mutations|Pedigree|High-Throughput Nucleotide Sequencing 27 ADGRV1 31951160 Curr. Pharm. Des. 2020 10.2174/1381612826666200116144147 0 0 0 90 *Cell Adhesion Molecules|*Dependence, Opioid|Dependence, Heroin|Neural Cell Adhesion Molecules|Cell Adhesion|Cadherins|Sialic Acids|*Biomarkers 27 ADGRV1 31914662 FASEB J. 2020 10.1096/fj.201901657RR 0 0 0 90 Mice|Animals|*Ankle|Mechanotransduction, Cellular|Usher Syndrome|Stereocilia|*Isoforms|Hair Cells, Auditory|PDZ Domain|USH2A protein, human|Extracellular Matrix Proteins|Carrier Proteins|Membrane Proteins|*Ankle Joint|Alternative Splicing|PDZD7 protein, mouse 27 ALX4 32650755 BMC Cancer 2020 PMC7350204 10.1186/s12885-020-07125-4 0 0 0 120 Humans|Female|miRNAs|*Oncogenesis|*Oncogenes|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|Biomarkers, Tumor|3' Untranslated Regions|Cell Line, Tumor|Down-Regulation|MIRN1908 microRNA, human 147 ALX4 32539762 Breast Cancer Res. 2020 PMC7294649 10.1186/s13058-020-01299-2 0 0 0 120 Humans|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Biomarkers, Tumor|Cell Movement 147 ALX4 32385972 Andrology 2020 10.1111/andr.12815 0 0 0 120 Humans|Male|Mice|Animals|Epispadias|Bladder Exstrophy|Genitourinary Tract Anomalies|Urogenital Abnormalities|Transcription Factor|Homeobox|Polymorphism, Single Nucleotide|Gene Expression Regulation|Mutations|*Urogenital System|ALX4 protein, human|DNA-Binding Proteins|Alx4 protein, mouse|Homeodomain Proteins 147 ALX4 32365604 Animals (Basel) 2020 PMC7278473 10.3390/ani10050773 0 0 0 120 Sheep|Animals|Humans|Breeding|Sheep, Domestic|Phenotype|Genotype|Polymorphism, Single Nucleotide|*Chinese|Genomics 147 ALX4 32216639 Genet Test Mol Biomarkers 2020 10.1089/gtmb.2019.0203 0 0 0 120 147 ALX4 31951012 J. Neurochem. 2020 10.1111/jnc.14962 0 0 0 120 Animals|Mice|resolvin D1|*Astrocytes|*Mice, Inbred C57BL|*Docosahexaenoic Acids|*Traumatic Brain Injury|*Mitochondria|Neurons|Hippocampus|*Cognitive Impairment|*Protective Agents|Gliosis|Reactive Oxygen Species|Neuroprotection|Inflammation|Cell Death 147 ALX4 31914496 Arch Craniofac Surg 2020 PMC6949507 10.7181/acfs.2019.00570 0 0 0 120 Humans|Frontonasal dysplasia|*Craniofacial Abnormalities|*Face|Hypertelorism|Abnormalities, Multiple|Phenotypes|Nose 147 ANKRD26 32659145 Platelets 2020 10.1080/09537104.2020.1790512 0 0 0 76 Humans|*5' Untranslated Regions|Egypt|*Mutations|Thrombocytopenia|*Genotype|Core Binding Factor Alpha 2 Subunit|Pedigree|Platelets|*Myeloproliferative Disorders|Genetic Predisposition to Disease|Nuclear Proteins|Malignancies, Hematological|ANKRD26 protein, human 68 ANKRD26 32618208 J Investig Med High Impact Case Rep 2020 10.1177/2324709620938941 0 0 0 76 Humans|Male|ANKRD26 protein, human|Nuclear Proteins|Myelodysplastic Syndrome|Thrombocytopenia chromosome breakage|Thrombocytopenia|Chromosome Disorders|Mutation|Chromosome Breakage|Pedigree|Genetic Predisposition to Disease|*Germ Line 68 ANKRD26 32571604 Mayo Clin. Proc. 2020 10.1016/j.mayocp.2019.12.013 0 0 0 76 Humans|*Hematopoietic Neoplasms|GATA2 protein, human|GATA2 Transcription Factor|*Genetic Predisposition to Disease|Myelodysplastic Syndromes|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Leukemia, Myeloid, Acute|Myeloproliferative Disorders|ANKRD26 protein, human|Nuclear Proteins|Neoplastic Syndromes, Hereditary|Mutation|Hematopoietic Stem Cell Transplantation|KDM1A protein, human|Histone Demethylases 68 ANKRD26 32366837 Nat Commun 2020 PMC7198521 10.1038/s41467-020-16042-w 0 0 0 76 Animals|*Cilia|Caenorhabditis elegans|Caenorhabditis elegans Proteins|ANKRD26 protein, human|*Nuclear Proteins|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|Genetic Testing|Cerebellum|Retina 68 ANKRD26 32351539 Front Genet 2020 PMC7174646 10.3389/fgene.2020.00340 0 0 0 76 Humans|Thrombocytopenia chromosome breakage|*Thrombocytopenia|*Chromosome Disorders|*Chromosome Breakage|Pedigree|Mutation|Genetic Predisposition to Disease|Nuclear Proteins|*Chinese 68 ANKRD26 31932033 Pathology 2020 10.1016/j.pathol.2019.10.005 0 0 0 76 Humans|*Blood Platelet Disorders|Platelet Function Tests|Platelet|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Thrombocytopenia|Platelet Count|Pedigree|Bleeding|Phenotype|Genetic Predisposition to Disease|Australia|DIAPH1 protein, human|Formins|ANKRD26 protein, human|Nuclear Proteins 68 APMAP 32272180 Life Sci. 2020 10.1016/j.lfs.2020.117609 0 0 0 44 Mice|Animals|*Obesity|*Adiposity|3T3-L1 Cells|Adipogenesis|Adipocytes|Anti-Obesity Agents|Adipose Tissue|Diet, High-Fat|PPAR gamma 19 atad5 32594826 Cell Cycle 2020 10.1080/15384101.2020.1785724 0 0 0 147 Humans|Centrosome|Centrioles|Mitosis|Chromosomal Instability|Chromosome Segregation|Genomic Instability|Aneuploidy|Cell Line, Tumor|ID1 protein, human|Inhibitor of Differentiation Protein 1|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities|DNA-Binding Proteins 35 atad5 32542338 Nucleic Acids Res. 2020 10.1093/nar/gkaa501 0 0 0 147 Humans|*Proliferating Cell Nuclear Antigen|*R-Loop Structures|Genomic Instability|DNA Replication|DNA Helicases|DNA|*Chromosome Structures|DNA-Binding Proteins|DEAD-box RNA Helicases|DHX9 protein, human|Neoplasm Proteins|DDX1 protein, human|DDX21 protein, human|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities 35 atad5 32358495 Nat Commun 2020 PMC7195461 10.1038/s41467-020-16096-w 1 0 0 147 Okazaki fragments|*Proliferating Cell Nuclear Antigen|*Chromatin Assembly and Disassembly|DNA|DNA Replication|*Ubiquitin|Genomic Instability|Ubiquitination|DNA Polymerases|Saccharomyces cerevisiae|DNA-Binding Proteins|*Chromosome Structures|Protein Binding|Genotoxic Stress|DNA2 protein, S cerevisiae|DNA Helicases|Saccharomyces cerevisiae Proteins 35 atad5 32297953 Nucleic Acids Res. 2020 PMC7229844 10.1093/nar/gkaa255 0 0 0 147 Mice|Animals|*Poly(ADP-ribose) Polymerase Inhibitors|*DNA Damage|DNA Replication|Replication Factor C|Proliferating Cell Nuclear Antigen|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Homologous Recombination|Genomic Instability|Adenosine Triphosphatases|DNA-Binding Proteins|ATPases Associated with Diverse Cellular Activities|DNA|Poly ADP Ribose Polymerase|Mutations|Methylmethane Sulfonate 35 C12orf65 32478789 Genet. Mol. Biol. 2020 PMC7263430 10.1590/1678-4685-GMB-2018-0271 0 0 0 45 Humans|*Leigh Disease|Mitochondrial Proteins|Homozygote|Optic Atrophy|Mitochondria|Oxidative Phosphorylation|Phenotype|Peptide Termination Factors|Pedigree|Genotype-Phenotype Correlation|Amino Acid Sequence|Mutation|C12orf65 protein, human 26 C12orf65 32425817 Front Psychiatry 2020 PMC7212438 10.3389/fpsyt.2020.00256 0 0 0 45 *Genetic Pleiotropy|Genome-Wide Association Study|Diabetes Mellitus, Type 2|*Schizophrenia|Quantitative Trait Loci|Genetic Predisposition to Disease|*Comorbidity|Polymorphism, Single Nucleotide|Coronary Artery Diseases|Risk Factors|*Biometry 26 C12orf65 31896602 J. Cell. Sci. 2020 10.1242/jcs.231811 0 0 0 45 Animals|*Mitochondrial Ribosomes|Ribosomes|Peptide Termination Factors|Protein Biosynthesis|Codon, Terminator|Escherichia coli Proteins|Mitochondria|RNA-Binding Proteins|*Bacteria|Escherichia coli|Protein Binding|RNA, Messenger|*Mammals 26 CAPS2 32655539 Front Immunol 2020 PMC7325944 10.3389/fimmu.2020.00865 0 0 0 10 Child|Adult|Humans|*Stomatitis, Aphthous|Retrospective Studies|*Pharyngitis|*Fever|Mevalonate Kinase Deficiency|Familial Mediterranean Fever|Hereditary Autoinflammatory Diseases|Cryopyrin Associated Periodic Syndromes|Adenitis|Amyloidosis|Interleukin 1|*Lymphadenopathy|Immunity, Innate 563 CAPS2 32648626 FASEB J. 2020 10.1096/fj.201902938RR 0 0 0 10 Animals|Mice|*Inflammasomes|*NLR Family, Pyrin Domain-Containing 3 Protein|Caspase 1|Cryopyrin Associated Periodic Syndromes|Pyrin Domain|CARD Signaling Adaptor Proteins|Interleukin-1beta|Apoptosis Regulatory Proteins|Apoptosis|Anti-Inflammatory Agents|Nlrp3 protein, mouse 563 CAPS2 32477355 Front Immunol 2020 PMC7241420 10.3389/fimmu.2020.00877 1 0 0 10 563 CAPS2 32373790 Lancet Rheumatol 2020 PMC7198216 10.1016/S2665-9913(20)30096-5 2 0 0 10 Adult|Humans|*Macrophage Activation Syndrome|*Interleukin 1 Receptor Antagonist Protein|*Lymphohistiocytosis, Hemophagocytic|*Cytokines|Adult Onset Still Disease|Arthritis, Juvenile|Antirheumatic Agents|Rheumatoid Arthritis|Cryopyrin Associated Periodic Syndromes|Immunosuppressive Agents|*Administration, Intravenous 563 CAPS2 32303815 Pathologe 2020 10.1007/s00292-020-00784-x 0 0 0 10 Sweet Syndrome|Pyoderma Gangrenosum|Skin Diseases, Vesiculobullous|Dermatitis|Cryopyrin Associated Periodic Syndromes|Urticaria|Psoriasis|Inflammation|Neutrophils|*Suppuration|Inflammasome 563 CAPS2 32303770 Hautarzt 2020 10.1007/s00105-020-04582-7 0 0 0 10 Hereditary Autoinflammatory Diseases|Inflammation|Immunity, Innate|Autoimmune Diseases|Syndrome|Skin|Amyloidosis|Diagnosis, Differential 563 CAPS2 32256502 Front Immunol 2020 PMC7093487 10.3389/fimmu.2020.00475 0 0 0 10 Hereditary Autoinflammatory Diseases|Familial Mediterranean Fever, Autosomal Dominant|Familial Mediterranean Fever|Inflammasomes|Autoimmune Diseases|Immunity, Innate|Syndrome|Fever|*Genetic Backgrounds 563 CAPS2 32194497 Front Neurol 2020 PMC7066252 10.3389/fneur.2020.00141 0 0 0 10 Humans|*Hearing Loss|*Deafness|Hearing Loss, Sensorineural|Cryopyrin-Associated Periodic Syndromes|NLR Family, Pyrin Domain-Containing 3 Protein|Inflammasomes|Ear, Inner|Cochlea|Interleukin-1beta|Mutations 563 CAPS2 32108029 Clin. Cancer Res. 2020 10.1158/1078-0432.CCR-19-3873 0 0 0 10 Humans|Male|*Prostate|Neoplasm Recurrence, Local|*Prostate Cancer|Prostate-Specific Antigen|*Disease Progression|Low Carbohydrate Diets|Weight Loss|*Chronic Disease|*Carbohydrate|CAPS2 protein, human|Calcium-Binding Proteins 563 CAPS2 32082075 Mediators Inflamm. 2020 PMC7012260 10.1155/2019/3293145 0 0 0 10 Humans|Adult|Child|Quality of Life|Familial Mediterranean Fever|Hereditary Autoinflammatory Diseases|Mevalonate Kinase Deficiency|Cryopyrin-Associated Periodic Syndromes|Autoimmune Diseases|Inflammation|Fever|Immunity, Innate|Amyloidosis|Phenotypes 563 CAPS2 32080084 Medicine (Baltimore) 2020 PMC7034626 10.1097/MD.0000000000019110 0 0 0 10 Humans|Female|Cold Hypersensitivity|Republic of Korea|*Cryopyrin-Associated Periodic Syndromes|*Feet|*Hands|Skin Temperature|Medicine, Korean Traditional|*Patient Compliance|Double-Blind Method|Treatment Outcome 563 CAPS2 32066461 Pediatr Rheumatol Online J 2020 PMC7027082 10.1186/s12969-020-0409-3 0 0 0 10 Child|Humans|*Mevalonate Kinase Deficiency|*Cryopyrin-Associated Periodic Syndromes|*Consensus|Hereditary Autoinflammatory Diseases|Familial Mediterranean Fever|Rheumatology|Fever|Inflammation|*Neoplasms|*Vascular Diseases 563 CAPS2 32065272 Pediatr Radiol 2020 10.1007/s00247-019-04536-9 0 0 0 10 Child|Humans|Periodic fever, familial, autosomal dominant|Hereditary Autoinflammatory Diseases|Familial Mediterranean Fever|Mevalonate Kinase Deficiency|Cryopyrin Associated Periodic Syndromes|Fever|Pyogenic arthritis, pyoderma gangrenosum, and acne|Pyoderma Gangrenosum|Inflammation|Autoimmune Diseases|Arthritis, Infectious|Acne|Rash 563 CAPS2 32059980 Am. J. Ophthalmol. 2020 10.1016/j.ajo.2020.02.002 1 0 0 10 Keratitis Fugax Hereditaria|NLRP3 protein, human|*NLR Family, Pyrin Domain-Containing 3 Protein|Keratitis, hereditary|*Keratitis|*Cornea|*Confocal Microscopy|Keratoplasty, Penetrating|Corneal Stroma|Tomography, Optical Coherence 563 CAPS2 31900383 Int J Oral Sci 2020 PMC6949296 10.1038/s41368-019-0068-8 4 0 0 10 Diabetes Mellitus, Type 2|Cryopyrin Associated Periodic Syndromes|*Periodontitis|Inflammation|Interleukin-1beta|Autoimmune Diseases|Rheumatoid Arthritis|Cytokines|Antibodies, Monoclonal|Antibodies, Monoclonal, Humanized|Gout 563 CDH23 32645618 Int. J. Pediatr. 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(Lond.) 2020 10.1113/JP279795 0 0 0 202 Mice|Animals|*Hair Cells, Auditory, Outer|Presbycusis|Cochlea|Evoked Potentials, Auditory, Brain Stem|Hearing|Aging|Molecular Motor Proteins|*Biophysics|Patch-Clamp Techniques|Genetic Predisposition 308 CDH23 32587610 Neural Plast. 2020 PMC7298343 10.1155/2020/8889264 0 0 0 202 Humans|Mice|Animals|*Chromosomes, Human, Pair 16|*Mice, Inbred C57BL|*Mice, Inbred DBA|Presbycusis|*Hearing|Auditory Threshold|Evoked Potentials, Auditory, Brain Stem|Allele|Phenotype|Cochlea|Genetic Predisposition to Disease|Genotype|Quantitative Trait Loci|*Hearing Tests|Deafness|Acoustic Stimulation 308 CDH23 32494297 Zool Stud 2020 PMC7262541 10.6620/ZS.2020.59-4 0 0 0 202 Animals|*Echolocation|*Shrews|Bats|Evolution, Molecular|Dolphins|Phylogeny|Selection, Genetic|Hearing|Adaptation, Physiological 308 CDH23 32485727 Audiol. 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Rep. 2020 10.3892/or.2020.7613 0 0 0 202 *Carcinoma, Renal Cell|*Whole Exome Sequencing|Kidney Neoplasms|*Cadherins|Prognosis|*Polymorphism, Genetic|Mutation|Biomarkers, Tumor|Sarcomas|Cell Differentiation|Cohort Studies 308 CDH23 32425987 Front Genet 2020 PMC7204213 10.3389/fgene.2020.00422 2 0 0 202 Male|Humans|Adult|Usher Syndrome|*Sequencing, Next-Generation|Retinitis Pigmentosa|Pedigree|DNA Mutational Analysis|Phenotypes|Heterozygote|Chinese|Mutation, Missense|Mutation|Cadherins|Family Members 308 CDH23 32327469 eNeuro 2020 PMC7210488 10.1523/ENEURO.0511-19.2020 0 0 0 202 Mice|Animals|*Parvalbumins|*Auditory Cortex|*Mice, Inbred C57BL|*Presbycusis|*Aging|Evoked Potentials, Auditory, Brain Stem|Auditory Threshold|Cochlea|Interneurons|Acoustic Stimulation 308 CDH23 32306668 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2020 10.3760/cma.j.issn.1001-9391.2020.02.002 0 0 0 202 308 CDH23 32276436 Genes (Basel) 2020 PMC7230562 10.3390/genes11040403 0 0 0 202 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*High-Throughput Nucleotide Sequencing|Mutations, Germline|Exome|Sequencing, Whole Exome|Genetic Predisposition to Disease|Mutation 308 CDH23 32176153 Otol. Neurotol. 2020 PMC7343220 10.1097/MAO.0000000000002615 0 0 0 202 *Hearing Loss, Noise-Induced|Otoacoustic Emissions, Spontaneous|Audiometry, Pure-Tone|Auditory Threshold|Acoustic Stimulation|*Music|*Polymorphism, Genetic 308 CDH23 32134349 Acta Otolaryngol. 2020 10.1080/00016489.2020.1730439 0 0 0 202 308 CDH23 32115674 J Genet Eng Biotechnol 2020 PMC7049540 10.1186/s43141-020-0021-4 0 0 0 202 Infant, Newborn|Humans|Deafness, Autosomal Recessive 12|Usher Syndrome, Type ID|Usher Syndromes|Mutation|Pedigree|Cadherins|Genotype|Phenotype|Sequencing, Whole Exome|Hair Cells, Auditory 308 CDH23 32101784 Hear. Res. 2020 10.1016/j.heares.2020.107926 0 0 0 202 Animals|Mice|*C57BL Mice|*Gene Editing|Presbycusis|Allele|Hearing|Evoked Potentials, Auditory, Brain Stem|Auditory Threshold|Cochlea|Cadherins|Phenotypes|Mutation|Cdh23 protein, mouse 308 CDH23 32090030 Int J Ophthalmol 2020 PMC7013795 10.18240/ijo.2020.02.04 0 0 0 202 Humans|*Retinal Dystrophies|*Chinese|Retinitis Pigmentosa|Usher Syndromes|Genes, Recessive|Pedigree|Exons|Genotype|Mutation|Phenotype|Extracellular Matrix Proteins|ATP-Binding Cassette Transporters 308 CDH23 32048449 Mol Genet Genomic Med 2020 PMC7196461 10.1002/mgg3.1177 1 0 0 202 Humans|Nonsyndromic Deafness|*Deafness|*Asian Continental Ancestry Group|Hearing Loss, Sensorineural|Connexins|Mutations|Pedigree|High-Throughput Nucleotide Sequencing 308 CDH23 32040524 PLoS ONE 2020 PMC7010238 10.1371/journal.pone.0228943 0 0 0 202 Animals|*Melatonin|*Presbycusis|Otoacoustic Emissions, Spontaneous|Evoked Potentials, Auditory, Brain Stem|Auditory Threshold|Aging|Hair Cells, Auditory|Antioxidants|Mitochondria|Disease Models, Animal 308 CDH23 32009898 Front Mol Neurosci 2020 PMC6974483 10.3389/fnmol.2019.00320 0 0 0 202 Mice|Animals|Mechanotransduction, Cellular|Hair Cells, Auditory|Stereocilia|Hair Cells, Auditory, Inner|Zebrafish|Membrane Proteins|Cadherins|Pcdh15 protein, mouse|Protein Precursors|PCDH15 protein, zebrafish|Zebrafish Proteins 308 CDKN2AIP 32011671 Biochem. J. 2020 PMC7054742 10.1042/BCJ20190733 0 0 0 154 RNA, Ribosomal|Exoribonucleases|Ribosomes|RNA, Precursor|Cell Nucleolus|RNA Processing, Post-Transcriptional|RNA Binding Protein|Repressor Proteins|3'-(1-butylphosphoryl)adenosine|*Complement Factor B 19 CEP120 32227267 Ann. Surg. Oncol. 2020 10.1245/s10434-020-08368-y 0 0 0 226 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Cell Cycle|Neoplasm Invasiveness|Carcinoma, Squamous Cell|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|Biomarkers, Tumor|Signal Transduction|*Cell Division|ANO9 protein, human|Anoctamins|Phospholipid Transfer Proteins 22 CEP120 31965052 Sci Rep 2020 PMC6974609 10.1038/s41598-020-58151-y 0 0 0 226 *Centrioles|Microtubule-Associated Proteins|Cell Cycle Proteins|Cells, Cultured 22 CERKL 32658961 Invest. Ophthalmol. Vis. Sci. 2020 10.1167/iovs.61.8.14 0 0 0 65 Mice|Humans|Animals|*Retinal Degeneration|*CRISPR-Cas Systems|Retinitis Pigmentosa|Retina|*Phenotype|Phosphotransferases (Alcohol Group Acceptor)|*CRISPR|*Disease Models, Animal|Mutations 57 CERKL 32646556 Ophthalmol Retina 2020 10.1016/j.oret.2020.02.009 0 0 0 65 Humans|*Cone-Rod Dystrophies|*Fundus Oculi|*Retinitis Pigmentosa|Lipofuscin|Fluorescein Angiography|*Retinal Cone Photoreceptor Cells|Retinal Pigment Epithelium|Ophthalmoscopy|Macular Degeneration|Tomography, Optical Coherence|Optical Imaging 57 CERKL 32641690 Sci Rep 2020 PMC7343876 10.1038/s41598-020-67792-y 0 0 0 65 Humans|Tunisia|*Retinal Dystrophies|Retinitis Pigmentosa|Leber Congenital Amaurosis|Phenotype|Genotype-Phenotype Correlations|Cone Rod Dystrophy|Pedigree|Usher Syndrome|Eye Proteins|Exome|Genotype|Mutation|ATP-Binding Cassette Transporters|Cohort Studies 57 CERKL 32411380 Hum Genome Var 2020 PMC7217820 10.1038/s41439-020-0100-8 0 0 0 65 Retinitis Pigmentosa|*Mutations|Pedigree|Genes, Recessive|Eye Proteins|Genetic Linkage|Retinal Dystrophies|Exon|Mutation, Nonsense|Lod Score|Electroretinography|Genotype 57 CERKL 32036094 J Mol Diagn 2020 10.1016/j.jmoldx.2020.01.003 0 0 0 65 Humans|Female|DNA Copy Number Variations|Comparative Genomic Hybridization|Retinitis Pigmentosa|DNA Mutational Analysis|Retinal Dystrophies|Sequencing, Next-Generation|Pedigree|Mutations|Genotype-Phenotype Associations|Eye Proteins|Phenotype|Genetic Counseling|Cohort Studies 57 CERKL 31960602 Mol Genet Genomic Med 2020 PMC7057118 10.1002/mgg3.1131 3 0 0 65 Humans|*Whole Exome Sequencing|*Retinitis Pigmentosa|*Chinese|Exome|Genes, Recessive|DNA Mutational Analysis|Pedigree|Eye Proteins|Mutation|High-Throughput Nucleotide Sequencing 57 CHD7 32658404 Otol. Neurotol. 2020 10.1097/MAO.0000000000002671 0 0 0 406 Humans|*Cochlear Implants|*Cochlear Implantation|*Hearing Loss|*Deafness|*Audiometries|Cochlea|Auditory Threshold|Hearing|*Cohort Studies 422 CHD7 32627857 Prenat. Diagn. 2020 10.1002/pd.5781 0 0 0 406 Pregnancy|Female|Humans|*Prospective Studies|*Exome|*Diagnostic Tests, Routine|*Ultrasonography, Prenatal|*Whole Exome Sequencing|*Abnormalities, Multiple|Fetuses|Prenatal Diagnosis|Genetic Testing 422 CHD7 32625235 Front Genet 2020 PMC7314916 10.3389/fgene.2020.00592 0 0 0 406 Humans|*CHARGE Syndrome|*Phenotype|*Genetic Testing|*Genotype|DNA Helicases|Mutations|Coloboma|Pedigree|DNA-Binding Proteins|Congenital Heart Defects|Choanal Atresia|Cohort Studies|CHD7 protein, human 422 CHD7 32612575 Front Endocrinol (Lausanne) 2020 PMC7308526 10.3389/fendo.2020.00368 0 0 0 406 422 CHD7 32611869 J Indian Soc Pedod Prev Dent 2020 10.4103/JISPPD.JISPPD_320_19 0 0 0 406 Infant, Newborn|Humans|*Choanal Atresia|*CHARGE Syndrome|*Nipples|*Nose|Coloboma|Heart Defects, Congenital|Mutation|Genitalia 422 CHD7 32573075 Mol Genet Genomic Med 2020 10.1002/mgg3.1372 0 0 0 406 Humans|Male|*DNA Helicases|CHARGE Syndrome|Kallmann Syndrome|Hypogonadism, Isolated Hypogonadotropic|*Chinese|Phenotype|Mutation|DNA-Binding Proteins|*Infertility|ACTH Deficiency, Isolated|Endocrine System Diseases|Adrenocorticotropic Hormone|Hypoglycemia|CHD7 protein, human 422 CHD7 32509017 Exp Ther Med 2020 PMC7271729 10.3892/etm.2020.8683 0 0 0 406 Humans|Female|Infant|*CHARGE Syndrome|DNA Helicases|Mutations|DNA-Binding Proteins|Pedigree|Phenotype|Marcus Gunn phenomenon|Heart Defects, Congenital|Blepharoptosis|Reflex, Abnormal 422 CHD7 32502225 PLoS ONE 2020 PMC7274392 10.1371/journal.pone.0234246 0 0 0 406 Humans|Infant, Newborn|Mice|Animals|Esophageal atresia with or without tracheoesophageal fistula|*Esophageal Atresia|*Exome|Tracheoesophageal Fistula|Trichorhinophalangeal Syndrome, Type I|*Langer-Giedion Syndrome|*Hair Diseases|*Nose|*Fingers|Prevalence|TRPS1 protein, human|DNA-Binding Proteins|Transcription Factors|ZFHX3 protein, human|Homeodomain Proteins|CHD7 protein, human|DNA Helicases|Zfhx3 protein, mouse 422 CHD7 32493418 Orphanet J Rare Dis 2020 PMC7268350 10.1186/s13023-020-01421-9 0 0 0 406 Humans|*Autism Spectrum Disorder|*Cross-Sectional Studies|*CHARGE Syndrome|Autism|Diagnostic and Statistical Manual of Mental Disorders|Phenotype|Behavioral Problems 422 CHD7 32477919 Transl Pediatr 2020 PMC7237969 10.21037/tp.2020.03.09 0 0 0 406 Male|Humans|Infant, Newborn|*CHARGE Syndrome|DNA Helicases|DNA-Binding Proteins|Phenotype|*Chinese|Mutation 422 CHD7 32436650 Acta Ophthalmol 2020 10.1111/aos.14427 0 0 0 406 Child|Young Adult|Humans|*Anophthalmos|*Microphthalmos|Ocular Prosthesis|Phenotype 422 CHD7 32431714 Front Immunol 2020 PMC7214791 10.3389/fimmu.2020.00830 0 0 0 406 Infant, Newborn|Mice|Animals|Humans|*DiGeorge Syndrome|Endothelial Cells|CHARGE Syndrome|Thymocytes|Forkhead Transcription Factors|Cells, Epithelial|Chromosome Deletion|Zebrafish|Mice, Nude|Cell Differentiation|*Animal Models 422 CHD7 32400067 Andrologia 2020 10.1111/and.13594 0 0 0 406 Humans|*Kallmann Syndrome|*Whole Exome Sequencing|DNA Copy Number Variations|Hypogonadism|Mutation|Extracellular Matrix Proteins|Pedigree|DNA Helicases|Nerve Tissue Proteins|Anosmia|DNA-Binding Proteins|Genetic Heterogeneity|Genotype 422 CHD7 32397072 Genes (Basel) 2020 PMC7288448 10.3390/genes11050522 0 0 0 406 Animals|*Camelids, New World|*Cytogenetic|Genome|In Situ Hybridization, Fluorescence|X Chromosome|Peru 422 CHD7 32384900 Head Face Med 2020 PMC7206710 10.1186/s13005-020-00224-4 0 0 0 406 *CHARGE Syndrome|DNA Helicases|Phenotype|DNA-Binding Proteins 422 CHD7 32350000 Cancer Immunol Res 2020 10.1158/2326-6066.CIR-19-0759 0 0 0 406 *RNA, Micro|*Glioma|Glioblastoma|*Extracellular Vesicles|Brain Neoplasms|Neoplastic Stem Cells|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|*Macrophage 422 CHD7 32341405 Sci Rep 2020 PMC7184603 10.1038/s41598-020-63928-2 0 0 0 406 Humans|*Connectome|*Heart Defects, Congenital|Exome|Mutation|Polymorphism, Single Nucleotide|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|ADNP protein, human|Nerve Tissue Proteins|Homeodomain Proteins|CHD4 protein, human|Mi-2 Nucleosome Remodeling and Deacetylase Complex 422 CHD7 32314193 Mol. Cell. Biochem. 2020 10.1007/s11010-020-03723-9 0 0 0 406 Humans|Female|Long Non-Coding RNA|*Prognosis|*Endometrial Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|Cell Movement|Apoptosis|Gastric Cancers|*Endometrium|CHD7 protein, human|DNA Helicases|DNA-Binding Proteins 422 CHD7 32267359 Arch Endocrinol Metab 2020 10.20945/2359-3997000000231 0 0 0 406 Humans|Female|Infant, Newborn|*CHARGE Syndrome|*Dwarfism, Pituitary|Recombinant Growth Hormone|Human Growth Hormone|Heterozygote|Mutations|Frameshift Mutation 422 CIB2 32430498 Biol. Reprod. 2020 10.1093/biolre/ioaa059 0 0 0 387 Humans|Male|Mice|Animals|*Haploidy|*Spermatogenesis|Testis|Infertility, Male|Spermatozoa|Mice, Knockout|CIB1 protein, human|Calcium-Binding Proteins|Cell Differentiation|Seminiferous Tubules 44 CPA1 32658084 Pancreas 2020 10.1097/MPA.0000000000001612 0 0 0 1982 Trypsin Inhibitor, Kazal Pancreatic|Chronic Pancreatitis|Chymotrypsin|Cystic Fibrosis Transmembrane Conductance Regulator|Trypsin|Genetic Predisposition to Disease|Mutation|Carrier Proteins 143 CPA1 32458105 J. Mol. Evol. 2020 10.1007/s00239-020-09952-2 0 0 0 1982 Animals|*Proteinases|*Cetacea|*Evolution, Molecular|Biological Evolution|Selection, Genetic|Phylogeny|pancreatic lipase related protein 2|*Lipase|Adaptation, Physiological|*Diet|Chymotrypsin|Trypsin 143 CPA1 32116022 Am. J. Physiol. Gastrointest. 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Cell Proteomics 2020 10.1074/mcp.RA120.002174 0 0 0 121 Adult|Humans|Aged|*Transient Receptor Potential Channels|*Proteome|*Salivation|Xerostomia|Saliva|Salivary Proteins|Capsaicine|Mouth|Minor Salivary Gland|Rinse, Mouth|piperine|Polyunsaturated Alkamides|Menthol|Oral Mucosa|cinnamic aldehyde|Acrolein|*Central Nervous System Stimulants|Piperidines 344 cst1 32575462 Diagnostics (Basel) 2020 PMC7344784 10.3390/diagnostics10060416 0 0 0 121 Humans|Female|*Endometriosis|*Genomics|Bioinformatics|Gene Ontology|Databases, Genetic|*In Silico|Gene Regulatory Networks|Gene Expression Profiling|Upregulation|Downregulation|Gene Expression|Embryo Implantation 344 cst1 32460303 Med. Sci. 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Pediatr. 2020 10.1016/j.jpeds.2020.05.052 0 0 0 22 Child|Humans|Kartagener Syndrome|Phenotypes|Cilia|Mutation|Genetic Association Studies|China 64 DNAI1 32353641 Radiother Oncol 2020 10.1016/j.radonc.2020.03.038 0 0 0 22 Humans|*Nasopharyngeal Carcinoma|*Nasal Epithelium|Nasal Polyps|Epithelial Cells|Epithelium|Cilia|Cells, Cultured|Cell Differentiation|Nasopharyngeal Neoplasms|Chemoradiotherapy 64 DNAI2 32541515 Medicine (Baltimore) 2020 PMC7302588 10.1097/MD.0000000000020682 0 0 0 30 Humans|*Nasopharyngeal Carcinoma|*DNA Methylation|*Prognosis|*B-DNA|Protein Interaction Maps|Gene Ontology|Gene Expression Profiling|Nasopharyngeal Neoplasms|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Computational Biology|Epigenesis, Genetic|Biomarkers, Tumor|Software|Microarray Analysis|China|Middle East|North Africa 30 DRC1 31960620 Mol Genet Genomic Med 2020 PMC7057087 10.1002/mgg3.1137 1 0 0 38 *DNA Copy Number Variations|Japan|Kartagener Syndrome|Axonemal Dyneins|Cilia|Exome|Mutation 45 EML4 32600123 Ther Adv Respir Dis 2020 PMC7328355 10.1177/1753466620935770 0 0 0 167 950 EML4 32596809 J. 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Pharmacol. 2020 10.1111/jphp.13315 0 0 0 167 ethylene urea|*Apoptosis|ALK protein, human|Anaplastic Lymphoma Kinase|*Protein Kinase Inhibitors|*Autophagy|*Imidazolidines|Lung Cancer|Cell Proliferation|Cell Line, Tumor|Cell Survival|Oncogene Proteins, Fusion|Reactive Oxygen Species 950 EML4 32563740 Lung Cancer 2020 10.1016/j.lungcan.2020.05.026 0 0 0 167 Humans|*Crizotinib|ALK protein, human|*Anaplastic Lymphoma Kinase|*Carcinoma, Non-Small-Cell Lung|*Prognosis|*Lung Neoplasms|Protein Kinase Inhibitors|Oncogene Proteins, Fusion|Antineoplastic Agents|Adenocarcinoma|Gene Rearrangement|Mutation|*Genomics|EML4-ALK fusion protein, human 950 EML4 32558295 EMBO Mol Med 2020 PMC7338803 10.15252/emmm.201911099 1 0 0 167 Humans|Mice|Animals|*Lung Cancer|Crizotinib|Carcinoma, Non-Small-Cell Lung|Anaplastic Lymphoma Kinase|Protein Kinase Inhibitors|ceritinib|Pyrimidines|Receptor Protein-Tyrosine Kinases|alvocidib|Piperidines|Drug Resistance, Neoplasm|Sulfones|Pyrazoles|Pyridines|Oncogene Proteins, Fusion|Mutations|Carbazoles|Cell Line, Tumor 950 EML4 32558067 Oncologist 2020 10.1634/theoncologist.2020-0075 0 0 0 167 Humans|*Lung Cancer|*Carcinoma, Non-Small-Cell Lung|Quality of Life|ALK protein, human|Anaplastic Lymphoma Kinase|*Protein Kinase Inhibitors|Receptor Protein-Tyrosine Kinases|lorlatinib|Lactams, Macrocyclic|Drug Resistance, Neoplasm|protein-tyrosine kinase p55(blk)|*src-Family Kinases|Tyrosine Kinase|Mutations 950 EML4 32556222 J. 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Pathol. 2020 10.1038/s41379-020-0578-0 0 0 0 167 Humans|Male|Female|Adult|Middle Aged|Aged|*Carcinoma, Renal Cell|In Situ Hybridization, Fluorescence|Kidney Neoplasms|*Kidney|Anaplastic Lymphoma Kinase|*Carcinoma|Receptor Protein-Tyrosine Kinases|Sequencing, Next-Generation|*B-Lymphocytes 950 EML4 32457845 Front Oncol 2020 PMC7225306 10.3389/fonc.2020.00726 0 0 0 167 Humans|*Nonsmall Cell Lung Cancer|Lung Neoplasms|ALK protein, human|Anaplastic Lymphoma Kinase|Oncogene Proteins, Fusion|*Chinese|Mutation|*Genomics|Gene Amplification|Biomarkers, Tumor|HMBOX1 protein, human|Homeodomain Proteins 950 EML4 32457407 Mod. Pathol. 2020 10.1038/s41379-020-0574-4 0 0 0 167 Humans|Adolescent|Adult|*Thyroid Carcinomas|Iodine Radioisotopes|Papillary Thyroid Carcinomas|Secretory breast carcinoma|Carcinoma|Receptor, trkC|Rearrangements, Gene|Gene Fusion|Immunohistochemistry|Oncogene Proteins, Fusion|Receptor, trkA|Thyroidectomy|Biomarkers, Tumor|Mutation|Sequencing, Next-Generation|Breast Neoplasms 950 EML4 32397295 Cancers (Basel) 2020 PMC7281569 10.3390/cancers12051196 0 0 0 167 Humans|Female|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|EGFR protein, human|Epidermal Growth Factor Receptor|*Oncogene|Molecular Targeted Therapies|Protein Kinase Inhibitors|Mutation|Genes, erbB-1|Adenocarcinoma|Gene Rearrangement|Antineoplastic Agents 950 EML4 32368168 Lung Cancer (Auckl) 2020 PMC7184117 10.2147/LCTT.S239675 0 0 0 167 950 EML4 32344689 Cancers (Basel) 2020 PMC7226408 10.3390/cancers12041054 0 0 0 167 ALK protein, human|Anaplastic Lymphoma Kinase|*Protein Kinase Inhibitors|NVP-TAE684|Pyrimidines|Receptor Protein-Tyrosine Kinases|*Cell Proliferation|Crizotinib|ceritinib|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Drug Resistance, Neoplasm|Oncogene Proteins, Fusion|Antineoplastic Agents|Pyrazoles|Cell Line, Tumor|Pyridines|Apoptosis 950 EML4 32325863 Int J Mol Sci 2020 PMC7215933 10.3390/ijms21082847 0 0 0 167 950 FAM111A 32165630 Nat Commun 2020 PMC7067828 10.1038/s41467-020-15170-7 0 0 0 19 *Trypsin|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|PARP Inhibitors|*Chromosome Structures|Poly(ADP-ribose) Polymerases|DNA Replication|DNA Damage|Cell Line, Tumor 19 FAT2 32648600 J. 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Genet. 2020 10.1007/s00439-020-02156-0 0 0 0 40 Humans|X-Linked Infantile Nystagmus|Nystagmus, Congenital|Genetic Diseases, X-Linked|Genetic Linkage|Pedigree|Chromosome Mapping|Lod Score|*Open Reading Frames|Mutations|Base Sequence|Cytoskeletal Proteins|Asian Continental Ancestry Group|Membrane Proteins|*Chromosome Structures|FRMD7 protein, human 79 FRMD7 32047156 Nat Commun 2020 PMC7012930 10.1038/s41467-020-14643-z 0 0 0 40 Mice|Animals|Primary Visual Cortex|*Retina|Visual Pathways|Motion Perception|Photic Stimulation|Orientation|Neurons|Motion 79 FUCA1 32314457 Cancer Sci. 2020 10.1111/cas.14427 0 0 0 69 Humans|*alpha-L-Fucosidase|*Down-Regulation|*Glioma|*Autophagy|Beclin 1|Gene Expression Regulation, Neoplastic|Fucose|Cell Line, Tumor|*Disease Progression|*Macrophage|Immunohistochemistry|Upregulation 69 FUCA1 32212809 Asian Pac. J. 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Genet. 2020 10.1111/cge.13793 0 0 0 407 Humans|Cross-Sectional Studies|Charcot-Marie-Tooth disease, Type 2K|Charcot Marie Tooth Disease|Charcot-Marie-Tooth disease, Type 2A|Charcot-Marie-Tooth disease, X-linked, 1|Myelin P0 Protein|Connexins|Gene Duplication|Genotype|Mutation|Gene Deletion|Sequencing, Next-Generation|Demyelinating Diseases|Europe|Brazil 170 GDAP1 32499647 Nature 2020 PMC7292783 10.1038/s41586-020-2263-3 0 0 0 407 Humans|Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Asian|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Case-Control Studies 170 GDAP1 32438208 Psychiatry Res 2020 10.1016/j.psychres.2020.112979 0 0 0 407 Female|Animals|Mice|*C57BL Mice|Hippocampus|Dentate Gyrus|CA1 Region, Hippocampal|*Smoke|Synaptic Plasticity|*Tobacco|Smoking 170 GDAP1 32337338 Neurol Genet 2020 PMC7164976 10.1212/NXG.0000000000000412 0 0 0 407 Humans|Genetic Testing|*Neuromuscular Diseases|High-Throughput Nucleotide Sequencing|DNA Copy Number Variations|Sequence Analysis, DNA|Genetic Predisposition to Disease|Mutation 170 GDAP1 32298515 Eur. 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Sci. 2020 10.1007/s10072-019-04219-1 0 0 0 407 *Charcot-Marie-Tooth Disease|Italy|Myelin P0 Protein|Myelin Proteins|Connexins|Genetic Testing|GTP Phosphohydrolases|Mutation|Mitochondrial Proteins 170 GNPTG 32651481 J. Hum. Genet. 2020 10.1038/s10038-020-0797-8 0 0 0 56 Humans|Female|Pregnancy|*Mucolipidoses|Transferases (Other Substituted Phosphate Groups)|Phenotype|Exons|Mutation|RNA Splicing|mannose-6-phosphate|Mannosephosphates|Genotype|*Asian Continental Ancestry Group|Mutation, Missense|Lysosomes|GNPTG protein, human|GNPTAB protein, human 50 GNPTG 32283951 Hum. Gene Ther. 2020 10.1089/hum.2020.034 0 0 0 56 *Mucolipidoses|*RNA|*Exon|Transferases (Other Substituted Phosphate Groups)|*Oligonucleotides, Antisense|Phenotype|Mutation|Lysosomes|*Oligonucleotides 50 GNPTG 32220096 Hum. Mutat. 2020 PMC7292759 10.1002/humu.24019 0 0 0 56 Humans|*Mutation, Missense|Mucolipidosis II|*Golgi Apparatus|*Endoplasmic Reticulum|Transferases (Other Substituted Phosphate Groups)|N-acetylglucosamine kinase|*Phosphotransferases (Alcohol Group Acceptor)|membrane-bound transcription factor peptidase, site 1|Proprotein Convertases|Lysosomes|Mutations|Phenotype|*Protein Domains|*Translocation, Genetic|Serine Endopeptidases|GNPTG protein, human|GNPTAB protein, human 50 GSDMC 32333499 Int. J. Immunogenet. 2020 10.1111/iji.12488 0 0 0 11 Humans|Female|Middle Aged|Intervertebral disc disease|*Intervertebral Disc Displacement|*Asian Continental Ancestry Group|*Intervertebral Disc Degeneration|Allele Frequency|Single Nucleotide Polymorphisms|Haplotype|Genetic Predisposition to Disease|Genetic Association Studies|Alleles|Lumbar Vertebrae|Odds Ratios|Case-Control Studies|Ethnic Groups|Risk Factors 19 GSDMC 32294153 Acta Biochim. Biophys. Sin. 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Funct. 2020 10.1247/csf.20028 0 0 0 96 *Axon Initial Segment|Autism Spectrum Disorder|Proteomics|Axons|Neurons|Hippocampus|Ankyrins|Cells, Cultured|Epilepsy 19 IGSF9 32321427 BMC Microbiol. 2020 PMC7178946 10.1186/s12866-020-01762-2 0 0 0 96 Humans|*Gastrointestinal Microbiome|*DNA Methylation|*Metabolome|*Colorectal Cancer|*Colonic Neoplasms|*Gene Expression|Colon|Carcinogenesis|Intestinal Mucosa 19 IMPG2 32580068 Clin Neurol Neurosurg 2020 10.1016/j.clineuro.2020.106028 0 0 0 17 *Medulloblastoma|*Proteomics|Cerebellar Neoplasms|*Gene Expression Profiling|Hedgehog Proteins|Wnt Proteins|beta Catenin|Biomarkers, Tumor 26 IMPG2 32265257 J. Neurosci. 2020 PMC7219290 10.1523/JNEUROSCI.2994-19.2020 0 0 0 17 Humans|Mice|Animals|*Proteoglycan|*Extracellular Matrix|Extracellular Matrix Proteins|Retina|Eye Proteins|Retinal Cone Photoreceptor Cells 26 IMPG2 32242237 Hum. Mol. 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Sci. 2020 10.1016/j.psj.2019.10.021 0 0 0 17 Male|Humans|Female|Animals|*Chickens|Oviducts|*Transcriptome Analysis|Artificial Insemination|Sperm|Fertility|Profile, Gene Expression|Uterus|Sequencing, RNA|Vagina|Gene Ontology|RNA, Messenger|Mucous Membrane|POSTN protein, human|Cell Adhesion Molecules|B3GNT7 protein, human|N-Acetylglucosaminyltransferases 26 IRX2 32422864 Int J Mol Sci 2020 PMC7278941 10.3390/ijms21103455 0 0 0 141 Humans|Mice|Animals|*Parkinson Disease|*Genes, Homeobox|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|Dopaminergic Neurons|Mice, Transgenic|Protein-Serine-Threonine Kinases|*Biomarkers|Mutation|Organoids 71 IRX2 32317088 BMB Rep 2020 PMC7262508 0 0 0 141 Humans|histone H3 trimethyl Lys4|*Histones|*Histone Code|*Triple Negative Breast Neoplasms|*Protein Processing, Post-Translational|Chromatin Immunoprecipitation|Epigenesis, Genetic|Methylation|Lysine|Promoter Regions, Genetic|Gene Expression 71 jph2 32592107 Basic Res. Cardiol. 2020 10.1007/s00395-020-0807-1 0 0 0 218 Humans|Mice|Rats|Animals|*Myocytes, Cardiac|junctophilin|*Calpain|*Membrane Proteins|Muscle Proteins|Heart Failure|Intercellular Junctions|polypeptide C|*Peptides|Mutation|junctophilin-2 protein, mouse 52 jph2 32173700 Int Heart J 2020 10.1536/ihj.19-372 0 0 0 218 Humans|Adult|*Myocytes, Cardiac|trimethyloxamine|*Excitation Contraction Coupling|*Methylamines|*Sarcolemma|Heart Failure|Ventricular Remodeling|Membrane Proteins 52 jph2 32053184 Cardiovasc. Res. 2020 10.1093/cvr/cvaa033 0 0 0 218 Humans|Adult|junctophilin|*Myocytes, Cardiac|*Calcium Channels, L-Type|*Membrane Proteins|Sarcoplasmic Reticulum|Ryanodine Receptors|*Membrane Microdomains|Calcium Signaling|Intercellular Junctions|Cardiac Diseases|Heart Failure 52 jph2 31959204 Clin Epigenetics 2020 PMC6972030 10.1186/s13148-020-0807-x 0 0 0 218 Humans|*DNA Methylation|*Stomach Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Gene Expression Profiling|Biomarkers, Tumor|*Nucleotide Motifs|Neoplasm Staging|Neoplasm Recurrence, Local|Disease Progression 52 KCNJ13 32546498 Genetics 2020 10.1534/genetics.120.303390 0 0 0 30 Animals|*Zebrafish|Potassium Channels, Inwardly Rectifying|Signal Transduction|Mutation 40 KCNJ13 32507954 Int Ophthalmol 2020 10.1007/s10792-020-01432-2 0 0 0 30 Child|Humans|*Retinal Dystrophies|Leber Congenital Amaurosis|*Eye Abnormalities|*Genetic Testing|DNA Mutational Analysis|Electroretinography|Pedigree|Eye Proteins|Nicotinamide-Nucleotide Adenylyltransferase|High-Throughput Nucleotide Sequencing|Mutation|Phenotype|Membrane Proteins|Tomography, Optical Coherence|*Videorecording|*Survey|Electrophysiology 40 KCNJ13 32437550 Invest. 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Sci. 2020 10.1167/iovs.61.5.38 0 0 0 30 Humans|*Retinal Pigment Epithelium|*Induced Pluripotent Stem Cells|*Gene Deletion|*Phagocytosis|Cell Line|Cell Differentiation|Eye Proteins|Potassium Channels, Inwardly Rectifying 40 KCNT1 32655623 Front Genet 2020 PMC7324798 10.3389/fgene.2020.00614 0 0 0 42 Animals|*Channelopathies|*Intellectual Disability|*Potassium|Mutations 123 KCNT1 32597768 Epileptic Disord 2020 10.1684/epd.2020.1168 0 0 0 42 Child|Male|Humans|*Focal Seizures|Epilepsies, Partial|Epilepsy|Electroencephalography|*Homozygote|*Epilepsy, Generalized|Mutations|Encephalopathies|Brain|Mutation, Missense|*Codon, Nonsense|TBC1D24 protein, human|Membrane Proteins|Nerve Tissue Proteins|FARS2 protein, human|Phenylalanine-tRNA Ligase|Mitochondrial Proteins 123 KCNT1 32593896 Epilepsy Res. 2020 10.1016/j.eplepsyres.2020.106398 0 0 0 42 Child|Humans|*Epileptic Syndromes|*Encephalopathy|Spasms, Infantile|Phenotypes|NAV1.2 Voltage-Gated Sodium Channel|KCNQ2 Potassium Channel|Genetic Testing|Genetic Predisposition to Disease|Mutation|Sequencing, Next-Generation|Age of Onset|India 123 KCNT1 32583416 Rev Neurol 2020 10.33588/rn.7101.2020142 0 0 0 42 123 KCNT1 32505479 Brain Dev. 2020 10.1016/j.braindev.2020.05.002 0 0 0 42 *Quinidine|*Antitussive Agents|*Focal Seizures|*Epilepsy|Epilepsies, Partial|Drugs, Antiepileptic|Electroencephalography|Potassium Channels|*Failure, Treatment|Nerve Tissue Proteins|Mutation|Potassium Channels, Sodium-Activated 123 KCNT1 32427350 Epilepsia 2020 10.1111/epi.16533 0 0 0 42 Child|Adult|Humans|*Genetic Testing|*Epilepsy|Genetic Predisposition to Disease|Mutation|*Organizations 123 KCNT1 32413583 Neuropharmacology 2020 10.1016/j.neuropharm.2020.107970 0 0 0 42 Humans|*Precision Medicine|Pyridoxine-dependent epilepsy|*Epilepsies|Ketogenic Diet|Channelopathies|Mutation|Sodium Channel Blockers|Quinidine|Oxcarbazepine|Phenytoin 123 KCNT1 32408169 iScience 2020 PMC7225746 10.1016/j.isci.2020.101100 0 0 0 42 *Epilepsy|Quinidine|Potassium Channels|Membrane Potentials|Nerve Tissue Proteins|Patch-Clamp Techniques|Mutation|Potassium Channels, Sodium-Activated 123 KCNT1 32167590 Epilepsia 2020 10.1111/epi.16480 1 0 0 42 Child|Humans|*Epilepsy|Epilepsies, Partial|Electroencephalography|Potassium Channels|Quinidine|Mutation|Nerve Tissue Proteins|*Cohort Studies|Potassium Channels, Sodium-Activated|KCNT1 protein, human 123 KCNT1 32081855 Sci Rep 2020 PMC7035262 10.1038/s41598-020-60028-z 0 0 0 42 Animals|Mice|*Gain of Function Mutation|*Motor Skills|*Seizure|Potassium Channels|Nerve Tissue Proteins|Electroencephalography|Mutation|*Learning|Potassium Channels, Sodium-Activated 123 KCNT1 32038177 Front Cell Neurosci 2020 PMC6992647 10.3389/fncel.2020.00001 1 0 0 42 Animals|Cricetinae|*Epilepsy|*Partial Seizures|Potassium Channels|Electroencephalography|Nerve Tissue Proteins|Cricetulus|Mutation|Potassium Channels, Sodium-Activated|CHO Cells 123 KCNT1 32003688 Curr Gene Ther 2020 10.2174/1566523220666200131142423 0 0 0 42 Animals|*Epilepsy|Seizure|Anticonvulsants|*Brain|Epilepsy, Temporal Lobe|*Gene Therapy|Potassium Channels|NMDA Receptors|Mutation|Disease Models, Animal|Genetic Vectors 123 KCNT1 31972370 Eur J Med Genet 2020 10.1016/j.ejmg.2020.103848 0 0 0 42 Child|Humans|Epilepsy|Encephalopathy|*Heterozygote|Phenotype|*Epilepsy, Generalized|Genetic Predisposition to Disease|Mutation|KCNC2 protein, human|Shaw Potassium Channels|KCNB1 protein, human|Shab Potassium Channels|KCTD7 protein, human|Potassium Channels 123 KCNT1 31926846 Eur. J. Paediatr. Neurol. 2020 10.1016/j.ejpn.2019.12.024 0 0 0 42 Humans|Infant|*Cannabidiol|*Prospective Studies|*Epilepsy|*Focal Seizures|CDKL5 deficiency disorder|Spasms, Infantile|Anticonvulsants|Epilepsies, Partial|Lennox Gastaut Syndrome|Electroencephalography|Epileptic Syndromes|*Mutations|Dravet Syndrome|Potassium Channel|Nerve Tissue Proteins|KCNT1 protein, human|Potassium Channels, Sodium-Activated 123 KCNT1 31914597 FASEB J. 2020 PMC6956700 10.1096/fj.201902366R 0 0 0 42 Humans|*Protein Phosphatase 1|Patch-Clamp Techniques|Potassium Channels|Membrane Potentials|Nerve Tissue Proteins|Microfilament Proteins|Neurons|Potassium Channels, Sodium-Activated|Signal Transduction|Actin|Mutations|Epilepsy|KCNT1 protein, human 123 KIAA0586 32432689 Cereb. Cortex 2020 10.1093/cercor/bhaa112 0 0 0 86 Humans|*Language|*Temporal Regions|*Brain|Corpus Callosum|Diffusion Tensor Imaging|Functional MRI|Anisotropy|Diffusion MRI|DACT1 protein, human|Nuclear Proteins|Adaptor Proteins, Signal Transducing 27 KIAA0586 32381069 BMC Med. Genet. 2020 PMC7204034 10.1186/s12881-020-01024-y 0 0 0 86 Humans|Male|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Syndrome|*Pituitary Gland, Posterior|*Retina|Phenotype|Cilia|Homozygote|*INDEL Mutation|*Death, Sudden|Pedigree|Mutation|*Epilepsy|Cell Cycle Proteins 27 KIAA0586 32080096 Medicine (Baltimore) 2020 PMC7034684 10.1097/MD.0000000000019169 0 0 0 86 *Orofaciodigital Syndromes|*Polydactyly|Short Rib-Polydactyly Syndrome|*Phenotype|Ciliopathy|Mutation|Ribs 27 KLHL7 32590884 Histopathology 2020 10.1111/his.14194 0 0 0 90 *Nephroma, Mesoblastic|*Proto-Oncogene Proteins B-raf|Proto-Oncogene Proteins c-ets|Receptor, trkC|Transcription Factors|DNA-Binding Proteins|*Mutations|Immunohistochemistry|Repressor Proteins|Kidney Neoplasms|Oncogene Proteins, Fusion|Fibrosarcoma|In Situ Hybridization, Fluorescence|Receptors, Nerve Growth Factor|Biomarkers, Tumor|ErbB Receptors 30 KLHL7 32466770 Genome Biol. 2020 PMC7325161 10.1186/s13059-020-02043-x 1 0 0 90 Humans|Child|*RNA|*Cancer|Precision Medicine|*Sequencing, RNA|*Base Sequence|Software|Algorithm|Computational Biology|High-Throughput Nucleotide Sequencing|Transcriptomes|*Whole Exome Sequencing|Gene Fusion 30 KLHL7 32411183 Front Genet 2020 PMC7198905 10.3389/fgene.2020.00413 0 0 0 90 Humans|*RNA, Long Noncoding|*Prognosis|*Laryngeal Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Carcinoma, Squamous Cell|Biomarkers, Tumor|Gene Regulatory Networks|Bioinformatic|Survival Analysis|Kaplan-Meier Estimate|Carcinogenesis|Receiver Operating Characteristic|Head and Neck Neoplasms|STC2 protein, human|Glycoproteins|Intercellular Signaling Peptides and Proteins 30 KLHL7 31953236 Eur J Med Genet 2020 10.1016/j.ejmg.2020.103849 0 0 0 90 Humans|Bohring syndrome|*BTB-POZ Domain|*Intellectual Disability|*Craniosynostoses|Crisponi syndrome|Facies|Hand Deformities, Congenital|Retinitis Pigmentosa 42|Retinitis Pigmentosa|Phenotype|Mutations|Homozygote|Trismus|Pedigree|Termination Codon, Premature|Hyperhidrosis|Sequencing, Whole Exome|Death, Sudden 30 LMOD2 32110997 Genes (Basel) 2020 PMC7140879 10.3390/genes11030244 0 0 0 42 Animals|*Chickens|*Lipid Metabolism|Pectoral Muscle|Meat|Gene Expression Profiling|Adipose Tissue|Muscle, Skeletal|Genes, cdc|*Biological Phenomena 19 LMOD2 31899774 PLoS ONE 2020 PMC6941805 10.1371/journal.pone.0226138 0 0 0 42 Mice|Animals|*Sarcomeres|*Actin Cytoskeleton|*Heart Failure|Muscle Proteins|Myocardium|Cardiomyopathy|Myocytes, Cardiac|Cytoskeletal Proteins|Muscle, Skeletal|Myocardial Contraction|Myopathy|Transgenic Mouse 19 LMOD3 32008911 Neuromuscul. Disord. 2020 10.1016/j.nmd.2019.12.005 1 0 0 46 Humans|Female|Pregnancy|Nemaline Myopathy|*Mutations|Muscle Proteins|Muscle, Skeletal|*Retinal Rod Photoreceptor Cells|Actins|Mutation, Missense|Biopsy 22 LOXHD1 32645618 Int. J. Pediatr. Otorhinolaryngol. 2020 10.1016/j.ijporl.2020.110143 0 0 0 9 Humans|*Mutation Rate|*Hearing Loss, Sensorineural|Sulfate Transporters|Connexins|Connexin 26|DNA Mutational Analysis|*Genes, rRNA|Deafness|Mutations|Gene Frequency|Membrane Transport Proteins|RNA, Ribosomal|Alleles|DNA, Mitochondrial|Asian Continental Ancestry Group|China|GJB3 protein, human|SLC26A4 protein, human 34 LOXHD1 32149082 Biomed Res Int 2020 PMC7049443 10.1155/2020/1685974 0 0 0 9 Infant, Newborn|Humans|Nonsyndromic Deafness|*Language|*Deafness|*Chinese|Hearing Loss, Sensorineural|Hearing Loss|Genes, Recessive|Pedigree|Mutations|Mutation, Missense|LOXHD1 protein, human|Carrier Proteins 34 LYPLAL1 32514184 Nat. Chem. Biol. 2020 10.1038/s41589-020-0555-4 0 0 0 45 Animals|Humans|Mice|*Enzyme Activators|Enzyme Inhibitors|Hydrolases|Chemistry, Medicinal 71 LZTR1 32642684 Neurooncol Adv 2020 PMC7212860 10.1093/noajnl/vdaa023 0 0 0 108 *Neuroma, Acoustic|Neurofibromatosis 2|Nerve, Vestibulocochlear|Cerebellopontine Angle|Tumor Microenvironment 80 LZTR1 32623905 Circulation 2020 10.1161/CIRCULATIONAHA.119.044794 0 0 0 108 80 LZTR1 32576656 J. Med. Genet. 2020 10.1136/jmedgenet-2020-107022 0 0 0 108 Humans|*Neuroma, Acoustic|Schwannomatosis|Neurofibromatoses|Neurilemmoma|Neurofibromatosis Type II|SMARCB1 Protein|Skin Neoplasms|Transcription Factors|Germ-Line Mutation|Prognosis 80 LZTR1 32575496 Genes (Basel) 2020 10.3390/genes11060671 0 0 0 108 Neurofibromatosis Type I|Sequencing, Next-Generation|Genetic Testing|Phenotypes|Mutation 80 LZTR1 32514133 Eur. J. Hum. Genet. 2020 10.1038/s41431-020-0658-0 0 0 0 108 Humans|*Noonan Syndrome|Phenotype|DNA Mutational Analysis|Heterozygote|Pedigree|Mutation|Genes, ras|Sequencing, Whole Exome|Transcription Factors|*Multifactorial Inheritance|Protein Stability 80 LZTR1 32339168 PLoS Genet. 2020 PMC7205319 10.1371/journal.pgen.1008727 0 0 0 108 Animals|Humans|*DiGeorge Syndrome|*Schizophrenia|*Chromosome Deletion|*Genes, Neurofibromatosis 1|*Sleep|Drosophila|Neurofibromin 1|Neurons|Phenotype|Signal Transduction|Genetic Susceptibility|Shprintzen Golberg craniosynostosis|Arachnodactyly|Craniosynostoses|Marfan Syndrome|LZTR1 protein, human|Transcription Factors 80 LZTR1 32281771 Clin. Orthop. Relat. Res. 2020 10.1097/CORR.0000000000001239 0 0 0 108 Humans|Schwannomatosis|*Germ-Line Mutation|*Neurofibromatoses|*Neurilemmoma|*Skin Neoplasms|SMARCB1 protein, human|SMARCB1 Protein|Neurofibromatosis 2|Transcription Factors|DNA-Binding Proteins|*Genotype|Mutation|Chromosomal Proteins, Non-Histone|Loss of Heterozygosity|Genetic Predisposition to Disease|Pedigree 80 LZTR1 32271143 Clin. Neuropathol. 2020 10.5414/NP301245 1 0 0 108 *Neurofibromatosis 2|*Nerve Sheath Neoplasms|Neurilemmoma|SMARCB1 Protein|*Cranial Nerve Neoplasms|Transcription Factors|Mutations|Diagnosis, Differential 80 LZTR1 32175818 Circ. Res. 2020 10.1161/CIRCRESAHA.119.315730 1 0 0 108 Humans|*Noonan Syndrome|Ubiquitination|Signal Transduction|Mutation|Transcription Factors|Protein Transport 80 LZTR1 31983691 No Shinkei Geka 2020 10.11477/mf.1436204137 0 0 0 108 Humans|Male|Adult|Middle Aged|Aged|Schwannomatosis|*Neurofibromatoses|*Schwannoma|*Skin Neoplasms|Neurofibromatosis 2|SMARCB1 protein, human|SMARCB1 Protein|Spinal Neoplasms|Diagnosis, Differential|Magnetic Resonance Imaging|Exophthalmos|Japan 80 LZTR1 31898229 Adv. Exp. Med. Biol. 2020 10.1007/978-981-15-1025-0_12 0 0 0 108 Humans|KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|*Cullin Proteins|NF-E2-Related Factor 2|Ubiquitin|Ubiquitination|Cell Cycle Proteins|RBX1 protein, human|Carrier Proteins|Ubiquitin-Protein Ligases|Intracellular Signaling Peptides and Proteins|Adaptor Proteins, Signal Transducing|Repressor Proteins|Protein Binding|*Tumorigenesis|KLHL20 protein, human 80 MPZ 32657446 J. Cell. Physiol. 2020 10.1002/jcp.29942 0 0 0 2030 Rats|Animals|*Myelin Sheath|fibroblast growth factor 21|Schwann Cells|*Fibroblast Growth Factors|Sciatic Nerves|Peripheral Nerve Injuries|*Signal Transduction|Remyelination|*Mitogens|Extracellular Signal Regulated Kinases|Mitogen-Activated Protein Kinase 14|Animals, Newborn 465 MPZ 32531375 Life Sci. 2020 10.1016/j.lfs.2020.117959 0 0 0 2030 Rats|Animals|*Resveratrol|*Schwann Cells|*Sciatic Neuropathy|*Peripheral Nerve Injuries|*Autophagy|Wallerian Degeneration|Sciatic Nerve|Myelin Sheath|Nerve Crush|Nerve Regeneration|Axons|Function Recovery|Microtubule-Associated Proteins|Crush Injuries 465 MPZ 32506583 Clin. Genet. 2020 10.1111/cge.13793 0 0 0 2030 Humans|Cross-Sectional Studies|Charcot-Marie-Tooth disease, Type 2K|Charcot Marie Tooth Disease|Charcot-Marie-Tooth disease, Type 2A|Charcot-Marie-Tooth disease, X-linked, 1|Myelin P0 Protein|Connexins|Gene Duplication|Genotype|Mutation|Gene Deletion|Sequencing, Next-Generation|Demyelinating Diseases|Europe|Brazil 465 MPZ 32448848 Dent Mater J 2020 10.4012/dmj.2019-216 0 0 0 2030 *Bicuspid|*Ceramic|zirconium oxide|Zirconium|yttria|Yttrium|Adhesive cement|Resin Cements|Glass Ionomer Cement|Materials Testing|Computer-Aided Design|lithia disilicate|Dental Porcelain|Zinc Phosphate Cement|*Prostheses 465 MPZ 32298515 Eur. J. Neurol. 2020 10.1111/ene.14260 0 0 0 2030 Humans|Hereditary Sensory and Motor Neuropathy|Charcot-Marie-Tooth Disease|Heterogeneities, Genetic|Mutation|Cohort Studies 465 MPZ 32201027 J Clin Neurosci 2020 10.1016/j.jocn.2020.03.014 0 0 0 2030 Adult|Humans|Charcot-Marie-Tooth disease, Type 2I|*Charcot-Marie-Tooth Disease|Zero, Myelin Protein|Myelin Proteins|Phenotype|Mutation|Genotype|Neural Conduction|*Polyneuropathies|*Neuritis 465 MPZ 32170207 Commun Biol 2020 PMC7070019 10.1038/s42003-020-0854-z 0 0 0 2030 Humans|Mice|Animals|Mpz protein, mouse|*Myelin P0 Protein|*Charcot-Marie-Tooth Disease|*Up-Regulation|Phenotypes|Myelin Proteins|Myelin|Mutation|Axons|Homozygote|Heterozygote|*Transcriptional Activation 465 MPZ 32154989 Mol Genet Genomic Med 2020 PMC7216811 10.1002/mgg3.1205 1 0 0 2030 Child|Humans|*Whole Exome Sequencing|Exome|Genetic Testing|Mutation|Neuromuscular Diseases|*Chinese 465 MPZ 32143001 Int. Immunopharmacol. 2020 10.1016/j.intimp.2020.106330 0 0 0 2030 Male|Mice|Animals|EPO protein, human|*Erythropoietin|Sciatic Neuropathy|*Epoetin Alfa|Nerve, Sciatic|*Recovery of Function|Peripheral Nerve Injury|Nerve Regeneration|Neuroprotective Effect|Oxidative Stress|*Trauma, Nervous System|Disease Models, Animal|*Gene Expression 465 MPZ 32057773 Exp. Eye Res. 2020 10.1016/j.exer.2020.107962 0 0 0 2030 Humans|*Graves Ophthalmopathy|*Oculomotor Muscles|*Proteomics|*Transcriptome|Graves Disease|ACTN3 protein, human|Actinin 465 MPZ 31923703 Bone 2020 10.1016/j.bone.2020.115225 0 0 0 2030 Animals|*Oryzias|*Myelin P0 Protein|*Fracture Healing|*Animals, Genetically Modified|Osteoblasts|Osteoclasts|enhanced green fluorescent protein|Green Fluorescent Proteins|Myelin|Signal Transduction|*Organogenesis 465 MPZ 31919945 J. Peripher. Nerv. Syst. 2020 10.1111/jns.12362 0 0 0 2030 Male|Humans|Middle Aged|*Polyradiculoneuropathy, Chronic Inflammatory Demyelinating|*Emblems and Insignia|Hereditary Sensory and Motor Neuropathy|Charcot-Marie-Tooth Disease|Mutation|*Misdiagnosis|Proteins|Diagnosis, Differential 465 MPZ 31902012 Neurol. Sci. 2020 10.1007/s10072-019-04219-1 0 0 0 2030 *Charcot-Marie-Tooth Disease|Italy|Myelin P0 Protein|Myelin Proteins|Connexins|Genetic Testing|GTP Phosphohydrolases|Mutation|Mitochondrial Proteins 465 MRAS 32658582 Endocr Pract 2020 10.4158/EP-2020-0277 0 0 0 281 609 MRAS 32652822 ESC Heart Fail 2020 10.1002/ehf2.12796 0 0 0 281 Humans|*Heart Failure|Angiotensin Receptor Antagonists|Stroke Volume|Mineralocorticoid Receptor Antagonists|Angiotensin-Converting Enzyme Inhibitors|Adrenergic beta-Antagonists|Hospitalization|Hyperkalemia|Registries|*Ambulatory Care Facilities|Renal Insufficiency, Chronic 609 MRAS 32646638 Heart Lung Circ 2020 10.1016/j.hlc.2020.04.012 0 0 0 281 Humans|*Heart Failure|Stroke Volume|Mineralocorticoid Receptor Antagonists|Angiotensin Receptor Antagonists|Angiotensin-Converting Enzyme Inhibitors|Guideline Adherence|Registries|Prospective Studies|Practice Patterns, Physicians' 609 MRAS 32628147 Anatol J Cardiol 2020 10.14744/AnatolJCardiol.2020.91771 0 0 0 281 Humans|*Heart Failure|Stroke Volume|*Outpatients|Ventricular Function, Left|Angiotensin Receptor Antagonists|Mineralocorticoid Receptor Antagonists|Angiotensin-Converting Enzyme Inhibitors|Adrenergic beta-Antagonists|Defibrillators, Implantable|Guideline Adherence|Registries|Prospective Studies 609 MRAS 32607863 Egypt Heart J 2020 PMC7326745 10.1186/s43044-020-00069-x 0 0 0 281 Humans|*ST Elevation Myocardial Infarction|Egypt|Percutaneous Coronary Intervention|*Registry|Myocardial Reperfusion|*Cardiology|Angioplasty, Balloon, Coronary|Myocardial Infarction|Thrombolytic Therapy|Hospital Mortality 609 MRAS 32592265 ESC Heart Fail 2020 10.1002/ehf2.12867 0 0 0 281 Humans|*Mineralocorticoid Receptor Antagonists|*Stroke Volume|*Heart Failure|*Prognosis|Ventricular Function, Left|Hospitalization|Treatment Outcome|Propensity Score 609 MRAS 32528533 Front Genet 2020 PMC7264416 10.3389/fgene.2020.00524 0 0 0 281 Humans|*Prognosis|*Colon Cancer|Gene Expression Regulation, Neoplastic|MicroRNAs|Gene Expression Profiling|Biomarkers, Tumor|Adenocarcinoma|Computational Biology|RNA, Messenger 609 MRAS 32521003 Neurosurgery 2020 10.1093/neuros/nyaa227 0 0 0 281 Humans|Female|*Intracranial Aneurysm|*Case-Control Studies|*Tobacco Smoke Pollution|*Non-Smokers|Hypertension|Risk Factors|Smoking|Prevalence 609 MRAS 32495899 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202005_21355 0 0 0 281 Humans|Gene Frequency|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|MRAS protein, human|*ras Proteins|Asian Continental Ancestry Group|Alleles|Genotype|*Atherosclerosis|Risk Factors 609 MRAS 32457631 Front Pharmacol 2020 PMC7225336 10.3389/fphar.2020.00658 0 0 0 281 Male|Humans|*Prostatic Hyperplasia|Quality of Life|*Lower Urinary Tract Symptoms|Adrenergic alpha-Antagonists|5-alpha Reductase Inhibitors|Phosphodiesterase Type 5 Inhibitors|Prostate|Muscarinic Antagonists|Drug Therapy, Combination|Enzyme Inhibitors|*Iatrogenic Disease|*Drug-Related Side Effects and Adverse Reactions 609 MRAS 32449674 Turk J Urol 2020 10.5152/tud.2020.19280 0 0 0 281 Humans|*Renal Artery|*Hand-Assisted Laparoscopy|*Kidneys|*Laparoscopy|*Tissue and Organ Harvesting|Nephrectomy|Living Donors|Kidney Transplantation|*Ureteral Diseases|Graft Survival|*Kidney Diseases|Retrospective Studies|Length of Stay|Postoperative Complications|Treatment Outcome 609 MRAS 32446323 Lancet 2020 10.1016/S0140-6736(20)30748-0 0 0 0 281 Humans|*Heart Failure|Stroke Volume|Angiotensin Receptor Blockers|Angiotensin-Converting Enzyme Inhibitors|Mineralocorticoid Receptor Antagonists|Adrenergic beta-Antagonists|Drug Therapy, Combination 609 MRAS 32445449 Curr. 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Heart J. 2020 PMC7239195 10.1093/eurheartj/ehaa373 16 0 0 281 Male|Female|Humans|Aged|angiotensin converting enzyme 2|*Peptidyl-Dipeptidase A|*Renin|COVID-19|*Angiotensin|*Aldosterone|severe acute respiratory syndrome coronavirus 2|Coronavirus Infections|Pneumonia, Viral|Pandemic|Betacoronavirus|*Mineralocorticoid Receptor Antagonists|Renin-Angiotensin-Aldosterone System|Angiotensin Receptor Antagonists|Angiotensin-Converting Enzyme Inhibitors|Coronavirus|AGT protein, human|*Angiotensinogen 609 MRAS 32387066 JACC Heart Fail 2020 10.1016/j.jchf.2019.12.015 0 0 0 281 Humans|*Heart Failure|*Stroke Volume|Angiotensin Receptor Antagonists|*Registry|Angiotensin-Converting Enzyme Inhibitors|Mineralocorticoid Receptor Antagonists|Adrenergic beta-Antagonists|*Comorbidity|Guideline Adherence|Hospitalization|Outpatient 609 MRAS 32329663 Circ. Res. 2020 10.1161/CIRCRESAHA.119.316427 0 0 0 281 *Mitral Valve Prolapse|*Aldosterone|NR3C2 protein, human|*Receptors, Mineralocorticoid|Mitral Valve Insufficiency|Mitral Valve|*Mineralocorticoids|Echocardiography|Fibrosis 609 MYNN 32309439 Biomed Res Int 2020 PMC7139879 10.1155/2020/8348147 0 0 0 15 Humans|*Alzheimer Disease|*Machine Learning|CpG Islands|DNA Methylation|Protein Interaction Maps|Gene Regulatory Networks|Epigenesis, Genetic|Gene Expression Profiling|Computational Biology|Databases, Genetic|*Genetic Markers|Impairments, Cognitive|Gene Expression Regulation, Neoplastic|Signal Transduction 19 MYNN 32296102 Sci Rep 2020 PMC7160122 10.1038/s41598-020-63510-w 0 0 0 15 Humans|*Diabetes Mellitus, Type 2|*Telomere|*Asian Continental Ancestry Group|Telomere Homeostasis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Case-Control Studies|Telomerase|Genotype|Leukocytes|Genetic Variation|*Blood Group Antigens|MYNN protein, human|Kruppel-Like Transcription Factors 19 MYO3A 32519820 Mol Genet Genomic Med 2020 10.1002/mgg3.1343 0 0 0 81 50 MYO3A 32451864 Adv. 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Biol. 2020 10.1007/978-3-030-38062-5_13 0 0 0 81 50 MYO3A 32006683 Eur J Med Genet 2020 10.1016/j.ejmg.2020.103869 0 0 0 81 Male|Humans|Female|fibulin|*Homozygote|*Mutation|Arachnodactyly|Telecanthus|Craniofacial Abnormalities|Marfan Syndrome|EFEMP1 protein, human|*Extracellular Matrix Proteins|Pedigree|Siblings|Mutation, Missense|Phenotype|Sequencing, Whole Exome|Connective Tissue Disease|Hearing Loss, Sensorineural|Codon, Nonsense 50 MYPN 32405922 Ir J Med Sci 2020 10.1007/s11845-020-02239-x 0 0 0 235 Humans|*Arrhythmias, Cardiac|*Athletes|Sports|Cardiomyopathy|Electrocardiography|Death, Sudden, Cardiac|Cardiomyopathy, Hypertrophic|*Genetic Association Studies|Screening|Phenotype|Genotype 32 MYPN 32355558 J Anim Sci Biotechnol 2020 PMC7187514 10.1186/s40104-020-00447-0 0 0 0 235 Animals|Swine|*Inbreeding|*Homozygote|Genotypes|Genome|Haplotypes|Single Nucleotide Polymorphisms 32 neat1 32670881 Front Oncol 2020 PMC7327087 10.3389/fonc.2020.00998 0 0 0 5 581 neat1 32669857 Onco Targets Ther 2020 PMC7336013 10.2147/OTT.S239432 0 0 0 5 *RNA, Long Noncoding|*Colorectal Cancer|*Apoptosis|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor|Up-Regulation|Disease Progression|*Colonic Neoplasms 581 neat1 32649883 Mol. 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Sci. Monit. 2020 PMC7154562 10.12659/MSM.919360 0 0 0 0 *Lythrum|Molecular Docking Simulation|Traditional Chinese Medicine|*Primulaceae|Drugs, Chinese Herbal|*Kidney Calculi|Signal Transduction|Software|Databases, Factual|Taiwan 2750 Purine salvage 32221330 Sci Rep 2020 PMC7101371 10.1038/s41598-020-62236-z 0 0 0 0 *Bacillales|Escherichia coli|*Antibiotic|Microbial Sensitivity Tests|Ralstonia solanacearum|Bacillus|Bacteria|Staphylococcus|Pathway, Biosynthetic 2750 Purine salvage 32211028 Front Genet 2020 PMC7068213 10.3389/fgene.2020.00179 0 0 0 0 Leishmania donovani|Leishmaniasis, Visceral 2750 Purine salvage 32029457 Genes Dev. 2020 PMC7050480 10.1101/gad.335109.119 3 0 0 0 *NAD|Poly(ADP-ribose) Polymerases 2750 Purine salvage 31991093 Cell Host Microbe 2020 10.1016/j.chom.2020.01.002 4 0 0 0 Animals|*Toxoplasma|Parasites|CRISPR|*Genomics|Metabolic Network|Phenotypes 2750 Purine salvage 31988175 Infect. 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Pharmacol. 2020 PMC7174878 10.1111/bph.14978 1 0 0 0 Humans|Mice|Animals|*Urate Oxidase|*Xanthine Dehydrogenase|*Hypoxanthine Phosphoribosyltransferase|*Mice, Knockout|Allopurinol|purine|*Purines|Hyperuricemia|Lesch-Nyhan Syndrome|Uric Acid|Xanthine|FYX-051|Pyridines|Nitriles 2750 Purine salvage 31916414 J Diabetes Investig 2020 10.1111/jdi.13207 0 0 0 0 Humans|*Xanthine|*Hypoxanthine|Oxidoreductase, Xanthine|*Obesity|Insulin Resistance|Uric Acid|Hyperuricemia|Chromatography, Liquid 2750 Purine salvage 31911608 Nat Commun 2020 PMC6946658 10.1038/s41467-019-13950-4 0 0 0 0 Humans|Male|*Up-Regulation|*Prostate|*Prostate Cancer|diamine N-acetyltransferase|Acetyltransferases|Polyamines|5'-methylthioadenosine phosphorylase|Purine-Nucleoside Phosphorylase|Spermine|Spermidine|*Transcriptional Activation|Methionine|*Biochemical Phenomena|*Metabolic Clearance Rate 2750 Purine salvage 31894729 Emerg Microbes Infect 2020 PMC6968694 10.1080/22221751.2019.1707716 0 0 0 0 *Transformylase|glycine amide|*Glycine|Escherichia coli Proteins|Phosphoribosylglycinamide Formyltransferase|Escherichia coli|exoribonuclease T|*Exoribonucleases|Crystallography, X-Ray|Ribonucleotides|Adenosine Triphosphate|Binding Sites|Acyltransferases|Amino Acid Sequence|Models, Molecular|Formates 2750 RNASEH2A 32509219 Am J Transl Res 2020 PMC7270022 0 0 0 81 *Drug Resistance, Neoplasm|Receptors, Estrogen|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Gene Expression Profiling|ribonuclease HII|Ribonuclease H 41 RNASEH2A 32213663 Aging (Albany NY) 2020 PMC7138582 10.18632/aging.102969 1 0 0 81 Humans|*Carcinoma, Hepatocellular|*Computational Biology|*Liver Neoplasms|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Upregulation|Prognosis|Gene Expression Profiling|Databases, Genetic|mRNA|Disease-Free Survival|Disease Progression 41 RNASEH2A 32099333 Drug Des Devel Ther 2020 PMC7007779 10.2147/DDDT.S237830 0 0 0 81 *Curcumin|*Tongue Neoplasms|*Computational Biology|Cell Proliferation|Apoptosis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Down-Regulation|Cell Survival 41 RNASEH2A 32062129 Stem Cell Res 2020 10.1016/j.scr.2019.101697 0 0 0 81 Humans|*SAM Domain and HD Domain-Containing Protein 1|*Sterile Alpha Motif|Nervous System Malformations|Autoimmune Diseases of the Nervous System|three prime repair exonuclease 1|Exodeoxyribonucleases|*Aicardi Syndrome|Phosphoproteins|HTT protein, human|*Huntingtin Protein|Ribonuclease H|Phenotype|Interferon-Induced Helicase, IFIH1|*Synapsins|Adenosine Deaminase|*Genomics|Mutation|Monomeric GTP-Binding Proteins 41 rtn2 32011236 Elife 2020 PMC7046470 10.7554/eLife.51918 0 0 0 109 *Endosperm|*Zea mays|*Endoplasmic Reticulum|*Autophagy|Endoplasmic Reticulum Stress|TYRP1 protein, human|*Membrane Glycoproteins|RTN1 protein, human|Nerve Tissue Proteins|Carrier Proteins|Cytosol|Homeostasis 23 s100a5 31903766 J. 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Weinheim 2020 10.1002/adma.202001848 0 0 0 302 *Catalysis|Carbon|Electrochemical Techniques|Oxidation-Reduction|Carbon Monoxide|Models, Molecular 6592 SACS 32642365 Cureus 2020 PMC7336671 10.7759/cureus.8455 0 0 0 302 Infant, Newborn|Humans|Infant|*Prospective Studies|*Pulmonary Surfactants|Respiratory Distress Syndrome, Newborn|Infant, Premature|Mechanical Ventilation|Continuous Positive Airway Pressure|*Surface-Active Agents|Endotracheal Intubation|Gestational Age|*Cohort Studies|United Arab Emirates 6592 SACS 32635326 Life (Basel) 2020 10.3390/life10070104 0 0 0 302 *Endosperm|*Genomic Imprinting|*Angiosperms|Seeds|Polyploidy|Plants|Fertilization 6592 SACS 32630313 Dent J (Basel) 2020 10.3390/dj8030066 0 0 0 302 Humans|*Lasers, Solid-State|flowable hybrid composite|*Composite Resins|Dentin-Bonding Agents|Dentin|Resin Cements|Tensile Strength|Shear Strength|phosphoric acid|Phosphoric Acids|Microscopy, Electron, Scanning 6592 SACS 32628446 ACS Appl Mater Interfaces 2020 10.1021/acsami.0c08940 0 0 0 302 phthalocyanine|*Catalysis|*Metals|*Indoles|Carbon|Nitrogen 6592 SACS 32622422 Acta Histochem. 2020 10.1016/j.acthis.2020.151572 0 0 0 302 Male|Humans|Mice|Animals|*Sertoli Cells|*Coculture Techniques|*Laminin|*Agar|*Adult Germline Stem Cells|Spermatogonia|Testes|Spermatogenesis|Seminiferous Tubules|Cell Differentiation|Cells, Cultured|Stem Cells|Cell Culture Techniques|Cell Proliferation|laminine|*Amino Acids, Diamino|Infertility, Male 6592 SACS 32622205 Theriogenology 2020 10.1016/j.theriogenology.2020.06.007 0 0 0 302 Animals|*Triploidy|Diploid|*Acids, Fatty|Fish Proteins|Liver|Nutritional Requirement|Atlantic Salmon 6592 SACS 32615284 J. 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A 2020 10.1002/ajmg.a.61593 0 0 0 182 Humans|*Shwachman-Diamond Syndrome|Proteomics|Exocrine Pancreatic Insufficiency|Lipomatosis|Bone Marrow Diseases|*Phenotype|Endocrine System 350 SBDS 32198344 Cell Death Dis 2020 PMC7083877 10.1038/s41419-020-2393-4 1 0 0 182 Humans|*Tumor Suppressor Protein p53|Ribosome|Ribosomal Proteins|Proto-Oncogene Proteins c-mdm2|Bone Marrow Diseases|Cell Proliferation|Transcription, Genetic|Cell Nucleus|Ubiquitination|Shwachman Bodian Diamond Syndrome|SBDS protein, human|Proteins 350 SBDS 32179797 Sci Rep 2020 PMC7075892 10.1038/s41598-020-61602-1 0 0 0 182 cadmium selenide|*Cadmium Compounds|*Selenium Compounds|*Quantum Dots|Luminescence|indium tin oxide 350 SBDS 32121162 Micromachines (Basel) 2020 PMC7142523 10.3390/mi11030254 1 0 0 182 Carbon Compounds, Inorganic|Silicon Compounds|Nanostructures|Temperature 350 SBDS 32104616 Cureus 2020 PMC7026866 10.7759/cureus.6676 0 0 0 182 Male|Female|*Shwachman-Diamond Syndrome|Exocrine Pancreatic Insufficiency|Lipomatosis|Bone Marrow Diseases|Pancytopenia|Neutropenia|*Liver 350 SBDS 32072276 Surg Endosc 2020 10.1007/s00464-020-07418-6 1 0 0 182 Humans|*Double-Balloon Enteroscopy|*Intestinal Diseases|Gastrointestinal Hemorrhage|Biopsy 350 SBDS 32037152 J. 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Genet. 2020 10.1097/YPG.0000000000000248 0 0 0 160 Humans|*Tardive Dyskinesia|*Exome|Dystonia, Primary|Dystonia|*Whole Exome Sequencing|TOR1A protein, human|Molecular Chaperones|Genetic Predisposition|Allele Frequency|Antipsychotic Agents|Single Nucleotide Polymorphisms|Mutations|Nuclear Proteins|DNA-Binding Proteins|Apoptosis Regulatory Proteins|THAP1 protein, human 208 SH3TC2 32671691 Acta Neurol Belg 2020 10.1007/s13760-020-01441-z 0 0 0 139 Male|Humans|Female|Middle Aged|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Retrospective Studies|Neurodegenerative Diseases|Turkey|C9orf72 Protein|DNA Repeat Expansion|Frontotemporal Dementia|Mutations|Genetic Testing|Motor Neuron|Genetic Predisposition to Disease|*Genotype|Cohort Study|SPG11 protein, human|Proteins|C9orf72 protein, human 77 SH3TC2 32637351 Front Oncol 2020 PMC7318790 10.3389/fonc.2020.00829 0 0 0 139 *fms-Like Tyrosine Kinase 3|*Leukemia, Myeloid, Acute|*Mutation|Prognosis 77 SH3TC2 32298515 Eur. J. 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Virol. 2020 10.1128/JVI.00442-20 0 0 0 145 Humans|*Hepadnaviruses|DNA, Circular|Duck hepatitis B virus|Hepatitis B virus|DNA, Viral|Hepatitis B, Chronic|Interferon-alpha|Virus Replication|Hepatocytes|Transcription, Genetic|Epigenesis, Genetic|Protein Processing, Post-Translational|Hep G2 Cells|Episomes 121 SMCHD1 32546545 Sci Signal 2020 10.1126/scisignal.aaz5599 0 0 0 145 Humans|*Dimerization|Arhinia, choanal atresia, and microphthalmia|Choanal Atresia|Facioscapulohumeral Muscular Dystrophy|Microphthalmos|Chromosomal Proteins, Non-Histone|Chromatin|Protein Domains|Arrhinia|Nose|Adenosine Triphosphatases|Mutation|Crystallography, Xray|SMCHD1 protein, human 121 SMCHD1 32467133 Neurology 2020 10.1212/WNL.0000000000009617 1 0 0 145 Humans|Facioscapulohumeral Muscular Dystrophy|Chromatin|Epigenesis, Genetic|*Homozygote|Chromosomal Proteins, Non-Histone|DNA Methylation|Homeodomain Proteins|Mutations|*Codon, Nonsense 121 SMCHD1 32100546 Ann. Otol. Rhinol. 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Oncol. 2020 10.1016/j.urolonc.2020.01.018 0 0 0 331 Humans|*Cystectomy|*Urinary Bladder Neoplasms|Neoplasm Recurrence, Local|*Lymph Node Dissection|*Lymph Node|Lymphatic Metastasis|*Urinary Bladder|Carcinoma|Disease-Free Survival|Treatment Outcome|Risk Factor 1034 spink1 32096345 Cancer Med 2020 PMC7163112 10.1002/cam4.2942 1 0 0 331 Humans|*Urinary Bladder Neoplasms|Prospective Studies|Reproducibility of Results|DNA Copy Number Variations|*Prognoses|lncRNA|Transcriptome|Gene Expression Profiling|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|miRNA|Kaplan-Meier Estimate|Immunotherapy|Cohort Studies|SPINK1 protein, human|Trypsin Inhibitor, Kazal Pancreatic 1034 spink1 32066292 J Invest Surg 2020 10.1080/08941939.2020.1728443 1 0 0 331 1034 spink1 32014997 J. Biol. Chem. 2020 PMC7076226 10.1074/jbc.RA120.012526 0 0 0 331 Humans|chymotrypsin C|*Trypsin Inhibitors|*Chymotrypsin|Trypsin|Trypsinogen|Amino Acid Sequence|Pancreas|Pancreatitis|Proteolysis|Peptides|Protein Processing, Post-Translational|Models, Molecular|Catalysis|SPINK1 protein, human|Trypsin Inhibitor, Kazal Pancreatic 1034 spink1 32011822 BJS Open 2020 PMC6996643 10.1002/bjs5.50231 0 0 0 331 *Acute Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Pancreatitis, Acute Necrotizing|Risk Factors 1034 spink1 31959826 Nat Commun 2020 PMC6971084 10.1038/s41467-019-14184-0 3 0 0 331 Humans|Male|Mice|Animals|*Prostate Cancer|*Trypsin Inhibitor, Kazal Pancreatic|*Androgen Antagonists|*Upregulation|*Cell Plasticity|Androgen Receptor Antagonists|Receptors, Androgen|*Transcriptional Activation|Prostate|Gene Expression Regulation, Neoplastic|Transcription Factors|Cell Line, Tumor|Cell Transformation, Neoplastic|Signal Transduction|Xenograft Model Antitumor Assays|Cell Proliferation|Oncogenesis|SPINK1 protein, human 1034 spink1 31923181 PLoS ONE 2020 PMC6953855 10.1371/journal.pone.0227059 0 0 0 331 Humans|Mice|Animals|*Trypsin Inhibitor, Kazal Pancreatic|Caco-2 Cells|*Gastrointestinal Microbiome|*Reperfusion|Ischemia-Reperfusion Injury|*Ischemia|Intestinal Mucosa|Mesenteric Vascular Occlusion|Mesenteric Ischemia|CASP3 protein, human|Pro-Caspase-3|Permeability|Mesentery|Inflammation|Malondialdehyde|Lung|Apoptosis 1034 spink1 31911942 Sci Adv 2020 PMC6938705 10.1126/sciadv.aax5576 1 0 0 331 Humans|*Cetuximab|*Colorectal Cancer|Bevacizumab|Antibodies, Monoclonal|Angiogenesis Inhibitors|Antineoplastic Agents|Camptothecin|Antibodies, Monoclonal, Humanized|Antineoplastic Combined Chemotherapy Protocols|ErbB Receptors|Disease-Free Survival|*Colonic Neoplasms|SPINK1 protein, human|Trypsin Inhibitor, Kazal Pancreatic 1034 spink1 31900721 Dig. 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Res. 2020 10.1007/s12253-020-00801-7 0 0 0 104 Humans|*HPV 16|*Viral Load|*Anal Cancer|Carcinoma, Squamous Cell|Human Papilloma Virus|Papillomavirus Infections|Cyclin-Dependent Kinase Inhibitor p16|DNA, Viral|Immunohistochemistry|Tumor Suppressor Protein p53 23 TANGO2 32260361 Materials (Basel) 2020 PMC7178687 10.3390/ma13071685 0 0 0 104 Surface Properties|Materials Testing|Diamond 23 TANGO2 32012982 J Clin Med 2020 PMC7073659 10.3390/jcm9020358 0 0 0 104 23 taok2 32582947 J. Infect. Dis. 2020 10.1093/infdis/jiaa367 0 0 0 143 *Listeria monocytogenes|*Vacuoles|hlyA protein, Listeria monocytogenes|Hemolysin Proteins|Bacterial Toxins|Heat-Shock Proteins|Cytosol|Cytoplasm|Cell Line 19 taok2 32321919 Blood Cancer J 2020 PMC7176632 10.1038/s41408-020-0309-2 0 0 0 143 Humans|Phosphatidylinositol 3-Kinases|Leukemia, Large Granular Lymphocytic|*Natural Killer Cells|STAT3 protein, human|STAT3 Transcription Factor|Mutations|STAT5B protein, human|STAT5 Transcription Factor|Genes, Regulator|*Cancer|Flow Cytometry|RSF1 protein, human|Nuclear Proteins|Trans-Activators 19 taok2 32320645 Cell Rep 2020 10.1016/j.celrep.2020.107536 0 0 0 143 Humans|Animals|Mice|*Endophenotypes|*Schizophrenia|*Amygdala|Orbitofrontal Cortex|*Hippocampus|Schizophrenic Psychology|Working Memory|Neural Pathways|Continuous Performance Task|Brain|Magnetic Resonance Imaging 19 taok2 32236130 PLoS ONE 2020 PMC7112214 10.1371/journal.pone.0230796 0 0 0 143 Humans|Male|Female|*Lung Adenocarcinoma|*Transcriptome Analysis|Lung Cancer|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|MicroRNAs|Databases, Genetic|Computational Biology 19 taok2 32041905 J. 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Natl. Acad. Sci. U.S.A. 2020 PMC7104395 10.1073/pnas.1912429117 0 0 0 196 Humans|Autism Spectrum Disorder|NAV1.1 Voltage-Gated Sodium Channel|Epilepsies, Myoclonic|Phenotypes|Brain|Mutation|Williams Syndrome|MAGEL2 protein, human|Proteins 267 TBR1 32070431 Clin Epigenetics 2020 PMC7029553 10.1186/s13148-020-0823-x 0 0 0 196 Humans|*DNA Methylation|Renal Cell Cancer|Kidney Neoplasms|CpG Islands|*Kidney|Promoter Regions, Genetic|Epigenesis, Genetic|Biomarkers, Tumor|DNA|Brain 267 TBR1 32005960 Eur. J. Hum. Genet. 2020 PMC7253452 10.1038/s41431-020-0571-6 1 0 0 196 Humans|Animals|Mice|*Intellectual Disability|*Autistic Disorder|*Phenotype|Autism Spectrum Disorders|Neurodevelopmental Disorders|T-Box Domain Proteins|Gene Expression Regulation|Transcription Factor|Mutation|Magnetic Resonance Imaging|Tbr1 protein, mouse|DNA-Binding Proteins 267 TBR1 31901976 Brain Struct Funct 2020 10.1007/s00429-019-02015-3 0 0 0 196 Animals|Mice|*Chickens|Telencephalon|Prosencephalon|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Neurons|Cell Movement|Amygdala|Tbr1 protein, mouse|DNA-Binding Proteins 267 TGM6 32426513 Neurol Genet 2020 PMC7188476 10.1212/NXG.0000000000000424 0 0 0 55 Spinocerebellar Ataxias|Pedigree|Mutation, Missense|Mutation|Transglutaminases 22 TGM6 32259886 J. Integr. Neurosci. 2020 10.31083/j.jin.2020.01.1203 0 0 0 55 22 tmem127 32677196 Cancer Med 2020 10.1002/cam4.3319 0 0 0 146 *Gastrointestinal Stromal Tumors|*Sunitinib|*Imatinib Mesylate|*Dasatinib|*Prospective Studies|Protein Kinase Inhibitors|Pyrimidines|Proto-Oncogene Proteins c-kit|Piperazines|Benzamides|Receptor, Platelet-Derived Growth Factor alpha|Pyrroles|Antineoplastic Agents|Indoles|Drug Resistance, Neoplasm|Disease-Free Survival|Mutation 111 tmem127 32595774 Eur Endocrinol 2020 PMC7308108 10.17925/EE.2020.16.1.72 0 0 0 146 Humans|Female|Middle Aged|*Pheochromocytoma|*Adrenal Gland Neoplasms|Adrenalectomy|Positron-Emission Tomography|Radiopharmaceuticals|Tomography, X-Ray Computed|Imaging, Magnetic Resonance 111 tmem127 32575117 J. Clin. Endocrinol. Metab. 2020 10.1210/clinem/dgaa396 0 0 0 146 Pheochromocytomas|Paragangliomas|Adrenal Gland Neoplasms|Germ-Line Mutation|Genetic Predisposition to Disease|*Membrane|Carcinoma, Renal Cell|Membrane Proteins|*Protein Transport|Kidney Neoplasms|*Cell Movement 111 tmem127 32526160 Cell Host Microbe 2020 PMC7342019 10.1016/j.chom.2020.04.024 0 0 0 146 Humans|Mice|Animals|*MHC Class II Molecules|*Nedd4 Ubiquitin Protein Ligases|Ubiquitination|Ubiquitin-Protein Ligases|*Salmonella|Ubiquitin|Endosomal Sorting Complexes Required for Transport|Dendritic Cells|Protein Binding|Membrane Proteins|WWP2 protein, human|TMEM127 protein, human 111 tmem127 32508744 Front Endocrinol (Lausanne) 2020 PMC7249266 10.3389/fendo.2020.00234 0 0 0 146 111 tmem127 32321919 Blood Cancer J 2020 PMC7176632 10.1038/s41408-020-0309-2 0 0 0 146 Humans|Phosphatidylinositol 3-Kinases|Leukemia, Large Granular Lymphocytic|*Natural Killer Cells|STAT3 protein, human|STAT3 Transcription Factor|Mutations|STAT5B protein, human|STAT5 Transcription Factor|Genes, Regulator|*Cancer|Flow Cytometry|RSF1 protein, human|Nuclear Proteins|Trans-Activators 111 tmem127 32295730 Best Pract. Res. Clin. Endocrinol. Metab. 2020 10.1016/j.beem.2020.101416 0 0 0 146 Humans|*Pheochromocytoma|*Paraganglioma|*Adrenal Gland Neoplasms|SDHD protein, human|Succinate Dehydrogenase|Germline Mutation|Genetic Screening|Mutation|Genetic Predisposition to Disease|Genotype|Membrane Proteins 111 TRIB1 32619350 Cell. Physiol. Biochem. 2020 10.33594/000000246 0 0 0 410 Humans|*Triple-Negative Breast Cancer|*Paclitaxel|Cell Line, Tumor|Cell Proliferation|Cell Survival|Signal Transduction|Gene Expression Regulation, Neoplastic|*Drug Resistance 198 TRIB1 32562350 Physiol Rep 2020 PMC7305239 10.14814/phy2.14416 1 0 0 410 Humans|*Muscle, Skeletal|*Mitochondria|Mitochondria, Muscle|Exercise|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Adaptation, Physiological|Oxygen Consumption|Transcription Factors|Obesity 198 TRIB1 32370221 Nutrients 2020 PMC7285234 10.3390/nu12051301 0 0 0 410 Humans|*Polymorphism, Single Nucleotide|*Coffee|*Asian Continental Ancestry Group|*Coronary Heart Disease|Gene Frequency|Intracellular Signaling Peptides and Proteins|Protein-Serine-Threonine Kinases|Genotype|Case-Control Studies|*Alcohol Drinking|TRIB1 protein, human 198 TRIB1 32256487 Front Immunol 2020 PMC7093384 10.3389/fimmu.2020.00307 0 0 0 410 Animals|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Phosphatidylinositol 3-Kinase|*Phosphatidylinositol 3-Kinases|STAT5A protein, human|*STAT5 Transcription Factor|INPP5D protein, human|*Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|*Phagocytosis|*Tumor Suppressor Proteins|myo-inositol-1 (or 4)-monophosphatase|Phosphoric Monoester Hydrolases|Signal Transduction|Macrophages|Phosphorylation|Cell Line 198 TRIB1 32242402 Acta Biochim. Pol. 2020 10.18388/abp.2020_5152 0 0 0 410 Mice|Animals|*Macrophages|Macrophage Activation|*Inflammatory Bowel Disease|Inflammation|MicroRNAs|Colitis|*Phenotype|Macrophages, Peritoneal|TRIB1 protein, human|Intracellular Signaling Peptides and Proteins|Lipopolysaccharides|Protein-Serine-Threonine Kinases|Up-Regulation|Disease Models, Animal|MIRN98 microRNA, mouse 198 TRIB1 32150623 J. Exp. Med. 2020 PMC7201917 10.1084/jem.20190888 0 0 0 410 Lymphocytic choriomeningitis virus|Lymphocytic Choriomeningitis|*Cell Differentiation|*Lymphocyte Activation|CD8-Positive T-Lymphocytes|Signal Transduction|*Hematopoiesis 198 TSPEAR 32391042 Front Genet 2020 PMC7193018 10.3389/fgene.2020.00232 0 0 0 2 Humans|Smooth Muscle Cells|Artery, Pulmonary|Long Non-Coding RNA|Muscle, Smooth, Vascular|Cell Proliferation|Apoptosis|Hypertension, Pulmonary|Cell Hypoxia|MicroRNAs|Hypoxia|Up-Regulation|Lung|Cells, Cultured 19 TSPEAR 32382578 Biomed Res Int 2020 PMC7180394 10.1155/2020/8765461 0 0 0 2 Humans|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*Prognosis|*Hepatitis B virus|*Liver Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|Gene Regulatory Networks|Disease-Free Survival|RNA, Messenger|Receiver Operating Characteristic|Area Under Curve|CABYR protein, human|Calcium-Binding Proteins|Phosphoproteins|TRIP13 protein, human|ATPases Associated with Diverse Cellular Activities 19 UNC13A 32627229 Ann. Neurol. 2020 10.1002/ana.25841 0 0 0 276 Humans|*Amyotrophic Lateral Sclerosis|Frontotemporal Dementia|C9orf72 Protein|Genetic Predisposition to Disease|Single Nucleotide Polymorphism|Nerve Tissue Proteins|Neuroimaging|*Phenotype 88 UNC13A 32392183 Aging (Albany NY) 2020 PMC7244046 10.18632/aging.103150 0 0 0 276 Pregnancy|Female|Humans|Animals|Rats|*Hippocampus|Prenatal Nutritional Physiological Phenomena|Prefrontal Cortex|Prenatal Exposure Delayed Effects|*Brain Disorders|*Regulatory Genes|Transcriptomes|Disease Models, Animal|Malnutrition 88 UNC13A 31980003 J. Neurogenet. 2020 10.1080/01677063.2019.1710146 0 0 0 276 Animals|*Mushroom Bodies|*Synapses|*Smell|Synaptic Vesicles|*Protein Isoforms|Drosophila Proteins|Drosophila|Drosophila melanogaster|Memory 88 USB1 32620997 J. Clin. Immunol. 2020 10.1007/s10875-020-00815-5 0 0 0 66 Male|Humans|Adult|Poikiloderma with Neutropenia|*Skin Abnormalities|*Neutropenia|Rothmund-Thomson Syndrome|Homozygote|Pedigree|Mutation|Siblings|*Connective Tissue Diseases|*Atrophy|*Osteomyelitis|Infections 34 USP9Y 32655042 Asian J. Androl. 2020 10.4103/aja.aja_25_20 0 0 0 19 Humans|Male|Azoospermia, Nonobstructive|Azoospermia|*Sequencing, Next-Generation|Oligozoospermia|Spermatogenesis|Genetic Predisposition to Disease|Infertility, Male|Polymorphism, Single Nucleotide|Alleles|Asian Continental Ancestry Group|Mutation|Cohort Studies|HSF2 protein, human|Heat-Shock Proteins|Transcription Factors|TAF4B protein, human|Transcription Factor TFIID|TATA-Binding Protein Associated Factors 80 USP9Y 32273824 Reprod. Med. Biol. 2020 PMC7138941 10.1002/rmb2.12321 0 0 0 19 Humans|Aged|Male|Adult|*Azoospermia|*Chromosomes, Human, Y|*Mosaicism|Infertility, Male|Chromosome Deletion|Spermatogenesis 80 VPS13A 32494755 Neurol Genet 2020 PMC7217656 10.1212/NXG.0000000000000426 0 0 0 118 Humans|*Neuroacanthocytosis|Vesicular Transport Proteins|*Phenotypic Variability|Sweden 113 VPS13A 32439941 Sci Rep 2020 PMC7242441 10.1038/s41598-020-64845-0 0 0 0 118 Chorea-Acanthocytosis|Neurons|Cell Death|Vesicular Transport Proteins|Calcium|Lithium|Neurodegenerative Disorder 113 VPS13A 32151030 Int J Mol Sci 2020 PMC7084777 10.3390/ijms21051797 1 0 0 118 Humans|*Neuroacanthocytosis|Neurodegenerative Diseases|Acanthocytes|*Neurons|*Axons|Vesicular Transport Proteins|Mutations 113 VPS13A 32131761 BMC Med. Genet. 2020 PMC7057524 10.1186/s12881-020-0983-8 0 0 0 118 *Neuroacanthocytosis|Neurodegenerative Diseases|Vesicular Transport Proteins|Mutations|Pedigree|Acanthocytosis 113 VPS13A 32056394 Mol Genet Genomic Med 2020 10.1002/mgg3.1179 0 0 0 118 *Neuroacanthocytosis|Acanthocytes|*Protein Transport|Vesicular Transport Proteins|Mutations|Base Sequence|DNA Sequencing|DNA 113 VPS13A 31969655 Sci Rep 2020 PMC6976666 10.1038/s41598-020-57929-4 0 0 0 118 Humans|Child|*Intellectual Disability|DNA Copy Number Variations|Prospective Studies|*Phenotypes|*Genotype|Genotype-Phenotype Correlations|Pedigree|Genetic Linkage|Mutations|Neurodevelopmental Disorders|Sequencing, Whole Genome|Epilepsy|Polymorphism, Single Nucleotide|SPG11 protein, human|Proteins 113 VPS13A 31943017 Hum. Mol. Genet. 2020 PMC7068118 10.1093/hmg/ddz318 0 0 0 118 Humans|Child|*Saccharomyces cerevisiae|Spastic Ataxia|*Optic Atrophy|*Spinocerebellar Ataxias|Saccharomyces cerevisiae Proteins|Cohen syndrome|*Intellectual Disability|*Muscle Spasticity|Chorea-Acanthocytosis|*Yeast, Dried|Vesicular Transport Proteins|Mitochondrial Membranes|*Protein Domains|*Mutation|*Binding Site|Cell Membrane|Developmental Disabilities|Fingers 113 VPS13A 31888525 BMC Med. Genet. 2020 PMC6938020 10.1186/s12881-019-0935-3 0 0 0 118 MSTN protein, human|*Myostatin|*Spinal Muscular Atrophies of Childhood|Muscular Atrophy, Spinal|*Genomics|Pedigree|Mutation 113 VPS13C 32507414 Neurobiol. Aging 2020 10.1016/j.neurobiolaging.2020.05.005 0 0 0 72 Humans|*Parkinson Disease|*Mutation|*Chinese|Homozygote|Autosomal Recessive Parkinsonism|Pedigree|Sequencing, Whole Exome|Age of Onset|Ubiquitin-Protein Ligases|*Protein Transport|Cohort Studies|VPS13C protein, human|Proteins 43 VPS13C 32267580 Mov. Disord. 2020 10.1002/mds.28037 0 0 0 72 *Parkinson Disease|Glucocerebrosidase|alpha-Synuclein|*Lysosomes|Genetic Predisposition to Disease|Mutation|Genotype 43 VPS13C 32042909 Neurol Genet 2020 PMC6984134 10.1212/NXG.0000000000000385 0 0 0 72 Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genotype|Parkinson Disease|Case-Control Studies 43 wdfy1 32477064 Front Cell Neurosci 2020 PMC7240114 10.3389/fncel.2020.00093 0 0 0 79 Mice|Animals|*Neurogenesis|*Schizophrenia|Nerve Tissue Proteins|Adaptor Proteins, Vesicular Transport 19 wdfy1 32296847 J. Neuropathol. Exp. Neurol. 2020 10.1093/jnen/nlaa017 0 0 0 79 Mice|Animals|*Lipocalin|*Iron|LCN2 protein, human|*Lipocalin-2|*Hippocampus|*Oxidative Stress|Obesity|Inflammation|Insulin Resistance|Neurodegenerative Diseases|*Mice, Inbred Strains|Upregulation|Hemeoxygenase 1|Matrix Metalloproteinase 9|Sorl1 protein, mouse|Receptors, LDL|Membrane Transport Proteins 19 wdfy1 32123095 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7084120 10.1073/pnas.1921381117 0 0 0 79 Mice|Animals|*Lymphangiogenesis|*Neoplastic Processes|*Disease Models, Animal|Lung Neoplasms|Prostaglandins|Cyp2c44 protein, mouse|Cytochrome P450 Family 2 19 WDR11 32612575 Front Endocrinol (Lausanne) 2020 PMC7308526 10.3389/fendo.2020.00368 0 0 0 50 36 WDR11 32469254 Circ Genom Precis Med 2020 10.1161/CIRCGEN.119.002670 0 0 0 50 Humans|*Genome-Wide Association Study|*Coronary Artery Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|European Continental Ancestry Group|Case-Control Studies|Risk Factors 36 zic2 32555352 Cancer Gene Ther. 2020 10.1038/s41417-020-0185-8 0 0 0 286 *Nasopharyngeal Carcinoma|*Down-Regulation|*Proto-Oncogene Proteins c-akt|Neoplasm Recurrence, Local|Nasopharyngeal Neoplasms|*Signal Transduction|MicroRNAs|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Cancer Stem Cells|Cell Movement|Carcinoma|Gene Regulatory Networks|Cell Line, Tumor|Upregulation 266 zic2 32532883 Cold Spring Harb Mol Case Stud 2020 PMC7304358 10.1101/mcs.a005348 0 0 0 286 Humans|Child|Chromosome 9p Deletion Syndrome|*Chromosome Deletion|Chromosome 9, partial trisomy 9p|*Trisomy|*Chromosome 9|Chromosome Duplication|Chromosome Banding|Translocation, Genetic|Karyotyping|Comparative Genomic Hybridization|Abnormalities, Multiple|In Situ Hybridization, Fluorescence|Developmental Disabilities|Karyotype|Chromosome 13 266 zic2 32420167 Transl Androl Urol 2020 PMC7215046 10.21037/tau.2020.01.12 0 0 0 286 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Prognosis|Neoplasm Staging|Kaplan-Meier Estimate|Disease-Free Survival|Biomarkers, Tumor|*Zinc Finger|*Cerebellum 266 zic2 32335883 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.05.013 0 0 0 286 *Holoprosencephaly|*Fetus|*Genetic Testing|Nuclear Proteins|Transcription Factors 266 zic2 32209730 Aging (Albany NY) 2020 PMC7138570 10.18632/aging.102928 0 0 0 286 266 zic2 32129551 Stem Cells 2020 10.1002/stem.3168 0 0 0 286 Humans|*Clustered Regularly Interspaced Short Palindromic Repeats|*Genes, Essential|*Mesoderm|*Cell Differentiation|Cell Lineage|Embryonic Stem Cells|Cardiomyocytes|Pluripotent Stem Cells|Signal Transduction|Basic Helix-Loop-Helix Transcription Factors|Organogenesis|Gene Expression Regulation, Developmental|ZIC2 protein, human|Nuclear Proteins|Transcription Factors 266 zic2 32115407 Genes Dev. 2020 PMC7111260 10.1101/gad.329474.119 0 0 0 286 Animals|*Germ Layer|POU5F1 protein, human|Octamer Transcription Factor-3|Pluripotent Stem Cells|Cell Lineage|Mouse Embryonic Stem Cells|Primitive Streak|Ectoderm|Cell Differentiation|Gastrulation|Gene Expression Regulation, Developmental|DNA Methylation|Proto-Oncogene Proteins|Embryo, Mammalian|Regulatory Sequences, Nucleic Acid|Embryonic Development 266 zic2 32066655 Oncogenesis 2020 PMC7026396 10.1038/s41389-020-0202-7 0 0 0 286 Humans|Mice|Male|Animals|*Prostate|*Cadmium|Mice, Nude|*Cell Transformation, Neoplastic|*Cells, Epithelial|GLI1 protein, human|Zinc Finger Protein GLI1|Prostate Cancer|Benign Prostatic Hyperplasia|Nuclear Proteins|Transcription Factors|Cell Line, Tumor|Signal Transduction|Gene Expression Regulation, Neoplastic|Stem Cell Renewal|Cell Nucleus 266 zic2 32064600 Int. 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Cancer 2020 10.1002/ijc.32922 0 0 0 286 Humans|Female|*Downregulation|STAT3 protein, human|*STAT3 Transcription Factor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|Nuclear Proteins|Up-Regulation|Genes, Tumor Suppressor|Carcinogenesis|siRNA|mRNA|ZIC2 protein, human|Transcription Factors 266 zic2 32022405 Am J Med Genet C Semin Med Genet 2020 10.1002/ajmg.c.31770 0 0 0 286 Humans|*Holoprosencephaly|*Congenital Heart Defects|Homeodomain Proteins|Eye Proteins|Hedgehog Proteins|Phenotypes|Mutation|Nerve Tissue Proteins|Chromosome Mapping|Base Sequence|*Comorbidity|Cohort Studies 266 zic2 31997540 Genes Cells 2020 10.1111/gtc.12753 0 0 0 286 Chick Embryo|Mice|Animals|*Neural Tube|*Neural Crest|SOX2 protein, human|*SOXB1 Transcription Factors|Enhancer Elements, Genetic|Octamer Transcription Factor-3|Transcription Factors|Gene Expression Regulation, Developmental|Embryo, Mammalian|Chromatin Immunoprecipitation 266 zic2 31976095 Case Rep Genet 2020 PMC6949681 10.1155/2019/7250838 0 0 0 286 Humans|Chromosome 13 ring|*Ring Chromosomes|*Mosaicism|*Chromosomes, Human, Pair 13|Karyotyping|Comparative Genomic Hybridization|Microcephaly|In Situ Hybridization, Fluorescence|Abnormalities, Multiple|Intellectual Disability|Karyotype|Agenesis, Corpus Callosum|Phenotype|Syndrome 266 zic2 31929751 Int. 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Biol. 2019 10.1007/978-3-030-27378-1_89 0 0 0 90 Humans|Mice|Animals|Usher syndrome, type 2A|Usher Syndromes|*Photoreceptor Cells|Late-Onset Retinal Degeneration|Retinal Degeneration|Retinitis Pigmentosa|Extracellular Matrix Proteins|Zebrafish|Membrane Proteins|Mutations|Electroretinography|Retina|*Membrane|Disease Models, Animal|Ush2a protein, mouse 27 ADGRV1 31792237 Sci Rep 2019 PMC6889277 10.1038/s41598-019-53560-0 1 2 0 90 Humans|Female|Male|*African Americans|*Analgesics, Opioid|European Continental Ancestry Group|SNPs|Dependence, Opioid|Genome-Wide Association Study|Genetic Predisposition to Disease|Alleles|*Sex Differences 27 ADGRV1 31379920 Front Genet 2019 PMC6650584 10.3389/fgene.2019.00639 1 0 0 90 Humans|*Whole Exome Sequencing|*Hearing Loss|Genes, Recessive|Pedigree|*Chinese|Exome|Connexins|*Family|Mutation|Phenotype|*Nuclear Families 27 ADGRV1 31231422 Front Genet 2019 PMC6558366 10.3389/fgene.2019.00501 1 0 0 90 *Usher Syndromes|Cuba|*Genetic Screening|Pedigree|Mutation|High-Throughput Nucleotide Sequencing|Adaptor Proteins, Signal Transducing|Europe|Africa|South America 27 ADGRV1 31046701 BMC Med. Genet. 2019 PMC6498547 10.1186/s12881-019-0777-z 1 0 0 90 Humans|*Usher Syndromes|*Deaf-Blind Disorders|Retinitis Pigmentosa|*Blindness, Legal|Pedigree|*Hearing|Genotype|Mutation|*Hearing Tests|Extracellular Matrix Proteins|*Vision Disorders 27 ADGRV1 30617060 Cold Spring Harb Perspect Med 2019 10.1101/cshperspect.a033142 3 0 0 90 Humans|Mice|Animals|Hair Cells, Auditory|Stereocilia|Cilia|Mechanotransduction, Cellular|Cadherins|Protein Precursors|Protein Tyrosine Phosphatase|Usher syndrome, type 2A|Usher Syndromes|STRC protein, human|Membrane Proteins|Pcdh15 protein, mouse|Cdh23 protein, mouse|Ush2a protein, mouse|Extracellular Matrix Proteins 27 ALX4 31791584 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.10.139 1 2 0 120 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Cell Proliferation|*Apoptosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Hep G2 Cells|3' Untranslated Regions|Cell Line, Tumor|Xenograft Model Antitumor Assays|Disease Progression 147 ALX4 31712445 Proc. 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Biol. 2019 PMC6589380 10.1016/j.ydbio.2019.04.008 3 0 0 120 Animals|*Ambystoma mexicanum|*Retinoic Acid|*Limbs|*Regeneration|*Signal Transduction|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Fibroblast Growth Factors|BMP2 protein, human|Nerve Tissue|*Biological Phenomena|Transforming Growth Factor beta 147 ALX4 30761081 Front Endocrinol (Lausanne) 2019 PMC6362414 10.3389/fendo.2019.00008 4 2 0 120 Humans|*Arabs|Diabetes Mellitus, Type 2|Genetic Predisposition to Disease|Genome-Wide Association Study|Genetic Loci|Polymorphism, Single Nucleotide|*Genetic Testing|Alleles|Genotype|*Phenotype|Cyclin-Dependent Kinase Inhibitor p16|Risk Factors 147 ALX4 30687385 Front Genet 2019 PMC6334744 10.3389/fgene.2018.00699 4 0 0 120 Sheep|Animals|*Genome|Genotype|Phenotype|Sheep, Domestic|Breeding|Polymorphism, Single Nucleotide|Livestock|Ethiopia|Middle East|Africa, Southern|Europe|China|Caribbean 147 ANKRD26 31801613 Clin Epigenetics 2019 PMC6894277 10.1186/s13148-019-0768-0 0 1 0 76 Humans|Mice|Animals|*Risk Factors|*Obesity|*Epigenesis, Genetic|CpG Islands|*Genes, Regulator|DNA Methylation|Promoter Regions, Genetic|ANKRD26 protein, human|Nuclear Proteins|Ankrd26 protein, mouse|DNA-Binding Proteins|Transcription Factors 68 ANKRD26 31425920 Cancer Genet 2019 10.1016/j.cancergen.2019.07.002 2 0 0 76 *Thyroid Cancer, Papillary|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Thyroid Neoplasms|Carcinoma, Papillary|Proto-Oncogene Proteins c-ret|Carcinoma|*Gene Fusion|Gene Rearrangement|ANKRD26 protein, human|*Nuclear Proteins|Oncogene Proteins, Fusion|*Genes, Regulator|Sequencing, Next-Generation 68 ANKRD26 31355141 Front Oncol 2019 PMC6636394 10.3389/fonc.2019.00624 0 0 0 76 68 ANKRD26 31281687 Case Rep Hematol 2019 PMC6589226 10.1155/2019/9357572 0 1 0 76 Humans|*Multiple Myeloma|ANKRD26 protein, human|*Nuclear Proteins|*Thrombocytopenia|Mutation|Myelodysplastic Syndrome|Leukemia, Myeloid, Acute|Pedigree|*Hematopoietic Stem Cell Transplantation|*Genes, Regulator|Genetic Predisposition to Disease|*Leukopenia|Intercellular Signaling Peptides and Proteins|Bone Marrow|Chromosome Breakage 68 ANKRD26 31273088 Haematologica 2019 PMC7049343 10.3324/haematol.2019.223966 2 0 0 76 Humans|eltrombopag|Prospective Studies|*Hydrazines|*Benzoates|*Pyrazoles|Thrombopoietin|Receptors, Thrombopoietin|Thrombocytopenia|Platelet Count|Transfusions, Platelet|Hemorrhage 68 ANKRD26 31203998 Best Pract Res Clin Haematol 2019 10.1016/j.beha.2019.05.001 0 0 0 76 Humans|Child|Aged|Myelodysplastic Syndromes|GATA2 protein, human|GATA2 Transcription Factor|Leukemia, Myeloid, Acute|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Turcot syndrome|Neoplastic Syndromes, Hereditary|Myeloproliferative Disorders|Mutations, Germline|Predispositions, Genetic|Mutations|Hematologic Neoplasms|Fanconi Anemia|Dyskeratosis Congenita|ANKRD26 protein, human|Nuclear Proteins|Brain Neoplasms 68 ANKRD26 31069978 Int J Lab Hematol 2019 10.1111/ijlh.12999 3 0 0 76 Humans|Myelodysplastic Syndromes|*Blood Platelet Disorders|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|*Myeloproliferative Disorders|Leukemia, Myeloid, Acute|Germline Mutation|Mutations|Genetic Predisposition to Disease|Thrombocytopenia|Bone Marrow|Genetic Counseling|ANKRD26 protein, human|Nuclear Proteins|Cytogenetic Abnormalities|Hematopoietic Stem Cell Transplantation|Megakaryocytes|*Germ Line 68 ANKRD26 30824690 Nat Commun 2019 PMC6397210 10.1038/s41467-018-08216-4 11 27 0 76 Animals|*Centrioles|*Electron Microscopy|Centrosomes|Microtubule|Cilia|Mitosis|Tomography, Electron|Cell Cycle Proteins|Cell Cycle|Cell Line 68 APMAP 31356650 PLoS Pathog. 2019 PMC6687193 10.1371/journal.ppat.1007914 1 1 0 44 Infant, Newborn|Humans|Dogs|Animals|Mice|Cytomegalovirus|Cytomegalovirus Infections|Viral Envelope Proteins|Virus Internalization|Cells, Epithelial|Viral Particles|Cells, Cultured|Fibroblasts|Membrane Glycoproteins|Virus Replication|Cell Line|Endothelial Cells|Cell Membrane|*Adipocyte|*Membrane Proteins 19 APMAP 30987997 Cancer Res. 2019 10.1158/0008-5472.CAN-18-3295 3 3 0 44 Humans|Male|*Epithelial-Mesenchymal Transition|*Prostate Cancer|*Prostate|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Xenograft Model Antitumor Assays|Cell Line, Tumor|Signal Transduction|Biomarkers, Tumor|Apoptosis|Upregulation|ErbB Receptors|*Cholesterol|EGFR protein, human 19 APMAP 30704515 Acta Neuropathol Commun 2019 PMC6354426 10.1186/s40478-019-0660-3 0 8 0 44 Humans|Animals|Mice|*Alzheimer Disease|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|Secretase|Senile Plaques|Brain|Disease Models, Animal|Memory Disorders|Membrane Proteins|Memory, Spatial|Autophagy 19 atad5 31875566 Cell Rep 2019 10.1016/j.celrep.2019.11.114 0 0 0 147 *Proliferating Cell Nuclear Antigen|Nuclear Proteins|Transcription Factors|DNA Replication|Replication Protein C|Saccharomyces cerevisiae Proteins|Chromatin|Saccharomyces cerevisiae|DNA|DNA-Binding Proteins|Adenosine Triphosphatases|ATPases Associated with Diverse Cellular Activities|Protein Binding|Carrier Proteins 35 atad5 31844045 Nat Commun 2019 PMC6914801 10.1038/s41467-019-13667-4 1 0 0 147 Mice|Animals|*Proliferating Cell Nuclear Antigen|Genomic Instability|DNA Replication|Rad51 Recombinase|Replication Origin|DNA Repair|DNA-Binding Proteins|Hydroxyurea|Protein Binding|ATAD5 protein, mouse|Adenosine Triphosphatases 35 atad5 31703719 Ital J Pediatr 2019 PMC6839219 10.1186/s13052-019-0718-7 0 0 0 147 Humans|*Neurofibromatosis 1|NF1 Microdeletion Syndrome|Neurofibromatoses|Chromosome Deletion|Craniofacial Abnormalities|Intellectual Disability|Learning Disabilities|Genes, Neurofibromatosis 1|Karyotyping|In Situ Hybridization, Fluorescence 35 atad5 31553917 Cell Rep 2019 PMC6878991 10.1016/j.celrep.2019.08.051 2 0 0 147 *Proteome|*Proliferating Cell Nuclear Antigen|Nuclear Proteins|Transcription Factors|Chromatin|DNA Replication|DNA Repair|DNA-Binding 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Cancer 2019 PMC7111256 10.1002/ijc.32334 2 4 0 147 Humans|*PR-SET Domains|Neoplasm Recurrence, Local|*Neuroendocrine Tumors|SETD1B protein, human|Histone-Lysine N-Methyltransferase|Sequencing, Whole Exome|Liver Neoplasms|Mutations|Prognosis|Transcription Factors|Tumor Suppressor Protein p53|*Gastrointestinal Neoplasms|Cell Proliferation|WDR5 protein, human|UBR4 protein, human|Calmodulin-Binding Proteins|Cytoskeletal Proteins|ATAD5 protein, human 35 C12orf65 31753091 Zhongguo Dang Dai Er Ke Za Zhi 2019 0 0 0 45 Humans|Male|Child|Female|Spastic paraplegia type 5A, recessive|Spastic Paraplegia, Hereditary|*Mutations|Pedigree|Exome|Optic Atrophy|Mitochondrial Proteins|Peptide Termination Factors|High-Throughput Nucleotide Sequencing|Paraplegia|Base Sequence|C12orf65 protein, human 26 C12orf65 31018531 Int J Mol Sci 2019 PMC6514570 10.3390/ijms20081981 2 0 0 45 *Ribosome|tRNA, peptidyl-|RNA, Transfer, Amino Acyl|Peptide Chain Termination, Translational|*Protein Biosynthesis|Peptide Termination Factors|tRNA|Escherichia coli|Eukaryotic Cells|Carboxylic Ester Hydrolases 26 CAPS2 31846928 J Int Adv Otol 2019 PMC6937186 10.5152/iao. 2019.6871 0 0 0 10 Female|Child|Humans|Middle Aged|*Cochlear Implantation|Wells syndrome|*Hearing Loss|*Deafness|Hearing Loss, Sensorineural|*Cellulitis|*Eosinophilia|Muckle-Wells Syndrome|Audiometry, Pure-Tone|Auditory Threshold|Hearing|Cochlea|Interleukin 1 Receptor Antagonist Protein|Interleukin 1|Cochlear Implant|canakinumab|Antibodies, Monoclonal 563 CAPS2 31777803 ACR Open Rheumatol 2019 PMC6857991 10.1002/acr2.1039 0 3 0 10 Humans|*NLR Family, Pyrin Domain-Containing 3 Protein|Muckle-Wells Syndrome|Inflammasomes|*Mutation|CARD Signaling Adaptor Proteins|Carrier Proteins|Interleukin-1beta|Monocytes|Portugal|NLRP3 protein, human 563 CAPS2 31769858 Rheumatology (Oxford) 2019 PMC6878846 10.1093/rheumatology/kez448 0 0 0 10 *Hereditary Autoinflammatory Diseases|*Schnitzler Syndrome|Cryopyrin Associated Periodic Syndromes|NLR Family, Pyrin Domain-Containing 3 Protein|Inflammasomes|Mevalonate Kinase Deficiency|Immunity, Innate|Carrier Proteins|Mutation 563 CAPS2 31734027 J. 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Sci. 2019 10.1016/j.jphs.2019.10.005 1 0 0 10 Humans|Mice|Animals|*Oxaliplatin|*Tadalafil|*Phosphodiesterase 5 Inhibitors|*Peripheral Neuropathy|Antineoplastic Agents|Organoplatinum Compounds|Dorsal Root Ganglion|Sciatic Nerves|Hyperalgesia|Cold Hypersensitivity|Cryopyrin-Associated Periodic Syndromes|Disease Models, Animal|Cancer 563 CDKN2AIP 31321674 Clin Transl Oncol 2019 10.1007/s12094-019-02174-z 1 0 0 154 *Esophageal Squamous Cell Carcinoma|*Whole Exome Sequencing|*Esophageal Neoplasms|Mutations, Germline|Exome|Mutations|Carcinoma, Squamous Cell|Genetic Predisposition to Disease|Pedigree|Penetrance 19 CEP120 31816441 Eur J Med Genet 2019 10.1016/j.ejmg.2019.103823 0 0 0 226 Male|Humans|Child, Preschool|Jeune syndrome|*Ellis-Van Creveld Syndrome|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|Eye Abnormalities|Ciliopathies|Abnormalities, Multiple|Cytoplasmic Dyneins|Mutation|Pedigree|Cilia|Homozygote|Cerebellum|Retina|Proteins|DYNC2H1 protein, human 22 CEP120 30988386 Sci Rep 2019 PMC6465297 10.1038/s41598-019-42577-0 1 32 0 226 Humans|*Centrioles|Jeune syndrome|Ellis-Van Creveld Syndrome|Cilia|Cell Cycle|Cell Cycle Proteins|Ciliopathies|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Microtubule-Associated Proteins|Eye Abnormalities|Abnormalities, Multiple|Cells, Cultured|Cerebellum|Mutation|Retina|Talpid3 protein, human|CEP120 protein, human 22 CEP120 30677029 PLoS Genet. 2019 PMC6345421 10.1371/journal.pgen.1007603 5 0 0 226 Humans|*Thinness|*Obesity, Morbid|Genome-Wide Association Study|Obesity|Body Mass Index|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Gene Frequency 22 CERKL 31306460 PLoS ONE 2019 PMC6629068 10.1371/journal.pone.0219322 1 0 0 65 Humans|*Coinfection|*HIV Infection|Mycobacterium tuberculosis|Tuberculosis|Transcriptome 57 CERKL 31082679 Stem Cell Res 2019 10.1016/j.scr.2019.101455 0 0 0 65 Humans|*Induced Pluripotent Stem Cells|*Siblings|*Retinitis Pigmentosa|*Mutation|*Homozygote|Cell Line|ceramide kinase|Phosphotransferases (Alcohol Group Acceptor)|Fibroblasts|Cell Differentiation 57 CERKL 30926958 Genet. 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Cell Fact. 2019 PMC6685171 10.1186/s12934-019-1177-y 4 1 0 1982 *Metabolic Engineering|*Acetyl Coenzyme A|*Escherichia coli|*Carbon|Phosphate Acetyltransferase|Acetates|Glucose|Metabolic Pathways 143 CPA1 31191472 Front Microbiol 2019 PMC6545926 10.3389/fmicb.2019.01120 0 0 0 1982 143 CPA1 31130962 Front Immunol 2019 PMC6509204 10.3389/fimmu.2019.00984 1 0 0 1982 143 CPA1 30952487 Am. J. Kidney Dis. 2019 10.1053/j.ajkd.2019.02.010 0 0 0 1982 Humans|*Acinar Cells|*Carcinoma, Islet Cell|Carcinoma, Acinar Cell|Pancreatic Carcinoma|*Pancreatic Neoplasms|Multiple Myeloma|Acute Kidney Injury|Diagnosis, Differential|Immunohistochemistry|*Antibodies|Carcinoma, Neuroendocrine 143 CPA1 30883245 J. Clin. Oncol. 2019 PMC6494358 10.1200/JCO.18.01512 6 0 0 1982 Humans|*Germ-Line Mutation|*Risk Factors|BRCA2 Protein|BRCA1 Protein|Carcinoma, Pancreatic Ductal|Pancreatic Cancer|*Pancreas|Genetic Testing|Genetic Predisposition to Disease|*Neoplastic Processes 143 CPA1 30868438 In Vitro Cell. Dev. Biol. 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Cancer 2019 PMC6717698 10.1530/ERC-19-0016 0 3 0 1982 Pregnancy|Male|Female|Child|Humans|Young Adult|Mice|Animals|Adult|*Obesity|Body Weight|Overweight|Adiposity|Diet|Weight Gain|*Pancreatic Cancer|Prenatal Exposure Delayed Effects 143 CPA1 30831323 Cell Mol Gastroenterol Hepatol 2019 PMC6476890 10.1016/j.jcmgh.2019.02.004 0 2 0 1982 *Exocrine Pancreas|*Cell Differentiation|*Morphogenesis|Acinar Cells|Homeodomain Proteins|Pancreas|Cell Proliferation|Gene Expression Regulation, Developmental|HNF1A protein, human|Hepatocyte Nuclear Factor 1-alpha 143 CPA1 30655386 Diabetes 2019 10.2337/db18-0224 3 3 0 1982 Humans|Mice|Animals|Human Induced Pluripotent Stem Cells|*Islets of Langerhans|Pancreas|Basic Helix-Loop-Helix Transcription Factors|Insulin-Secreting Cells|Cell Differentiation|Homeodomain Proteins|Signal Transduction|Azepines|Nerve Tissue Proteins|*Neuroendocrine Cells|Cell Proliferation 143 Crb2 31795518 Genes (Basel) 2019 PMC6947654 10.3390/genes10120987 2 0 0 140 Infant, Newborn|Humans|*Retina|Leber Congenital Amaurosis|*Organogenesis|Retinal Degeneration|Nerve Tissue Proteins|Membrane Proteins|Organoids|Human Embryonic Stem Cell|Cell Differentiation|Stem Cell|Cell Polarity|Signal Transduction|*Fetus 178 Crb2 31718797 Biochem. 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Dis. 2019 PMC6734288 10.1186/s12879-019-4429-x 1 0 0 140 Humans|*Tuberculosis|Rifampin|Treatment Duration|Regimen B|Leucovorin|Antineoplastic Combined Chemotherapy Protocols|Carboplatin|Fluorouracil|Methotrexate 178 Crb2 31443145 Materials (Basel) 2019 PMC6720434 10.3390/ma12162593 0 0 0 140 *Steel|*Nickel|*Blood Platelets|*Excipients|Alloys|Stainless Steel|Plasma|Electroplating|Powders|Industry|Ceramic|Emollients|Histological Techniques|Research Design 178 Crb2 31209189 Iran J Kidney Dis 2019 0 0 0 140 Child|Humans|Nephrosis, congenital|*Nephrotic Syndrome|DNA Mutational Analysis|Intracellular Signaling Peptides and Proteins|Mutations|Membrane Proteins|WT1 Proteins|Exons|Genetic Predisposition to Disease|Steroids 178 Crb2 31196032 BMC Cancer 2019 PMC6567492 10.1186/s12885-019-5805-z 0 0 0 140 United States|Humans|Male|MDV 3100|*Prostate-Specific Antigen|*Prostatic Neoplasms|*Double-Blind Method|Androgen Antagonists|Neoplasm Recurrence, Local|*Prostatectomy|*Prostate|*Seminal Vesicles|*Salvage Therapy|*Phenylthiohydantoin|*Chronic Disease|Androgen Receptor Antagonists|Drug-Related Side Effects and Adverse Reactions|Hormone Replacement Therapy|Food and Drug Administration|Goals|Probability 178 Crb2 31145883 Dev. Biol. 2019 10.1016/j.ydbio.2019.05.008 0 1 0 140 Humans|Mice|Animals|*Leber Congenital Amaurosis|Retinitis Pigmentosa 12|Retinitis Pigmentosa|Retina|Electroretinography|Photoreceptor Cells|Membrane Proteins|Retinal Degeneration|Nerve Tissue Proteins|Eye Proteins|Ependymoglial Cells|Mice, Knockout|Mutations|Disease Models, Animal|Neuroglia|Progenitor Cells|CRB1 protein, human|CRB2 protein, human 178 Crb2 30996265 Sci Rep 2019 PMC6470164 10.1038/s41598-019-42549-4 3 0 0 140 Child|Infant|Animals|Humans|*Tomography, Optical Coherence|Hydrocephalus, X-linked|*Congenital Hydrocephalus|Cerebral Ventricles|Genetic Diseases, X-Linked|L1CAM|*Computers|Ependyma|*Physical Phenomena|Hemispherectomy|Cilia|Refraction, Ocular|CRISPR|Gene Editing|Anura 178 Crb2 30956116 Stem Cell Reports 2019 PMC6522954 10.1016/j.stemcr.2019.03.002 6 0 0 140 Humans|Mice|Animals|Female|Pregnancy|*Induced Pluripotent Stem Cells|*Retina|*Fetus|*Prenatal Care|*Glia|Organoids|*Apiaceae|Neurons|Protein Processing, Post-Translational|Proteomics|Serotype|Transducers|CRB1 protein, human|Eye Proteins|Membrane Proteins|Nerve Tissue Proteins|CRB2 protein, human|Carrier Proteins 178 Crb2 30811481 PLoS ONE 2019 PMC6392294 10.1371/journal.pone.0212365 1 0 0 140 *Mycobacteriophages|Mycobacterium smegmatis|Phages|Siphoviridae|Mycobacterium tuberculosis|Nucleotides|Sequence Homology, Nucleic Acid|Bioinformatics|Cactaceae|Diagnostic Tests, Routine|Reproduction|Screening|Specimen Handling 178 cst1 31841701 Infect. 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Physiol. 2019 10.1002/jcp.28493 0 1 0 145 Mice|Animals|*EIF-2|salubrinal|*Erythropoiesis|*Thiourea|*Cinnamates|Endoplasmic Reticulum Stress|Apoptosis|Phosphorylation|Cell Differentiation 19 DDRGK1 30842412 Nat Commun 2019 PMC6403283 10.1038/s41467-019-08908-5 5 52 0 145 *Plasma Cells|*Unfolded Protein Response|X-Box Binding Protein 1|Endoribonucleases|eIF-2 Kinase|Activating Transcription Factor 6|Protein-Serine-Threonine Kinases|Endoplasmic Reticulum Stress|Endoplasmic Reticulum|Signal Transduction|Transcription Factors|DNA-Binding Proteins|Upregulation 19 ddx3y 31877875 Animals (Basel) 2019 PMC7023270 10.3390/ani10010031 0 0 0 71 Male|Animals|*Genes, Y-Linked|*Buffaloes|*DNA Copy Number Variations|Y Chromosome|*Bison|Spermatogenesis|*Swamp 104 ddx3y 31817322 Genes (Basel) 2019 PMC6947224 10.3390/genes10121010 0 0 0 71 Female|Male|Pregnancy|Swine|Animals|*Sex Determination Analysis|Sex Differentiation|Sequence Analysis, RNA|Transcriptome|Sexual Dimorphism|Embryo, Mammalian|Gene Expression Regulation, Developmental|Fetuses|RNA 104 ddx3y 31781421 Case Rep Genet 2019 PMC6874946 10.1155/2019/3802613 0 0 0 71 Humans|Male|Infertility, Male|Spermatogenesis|Azoospermia|Chromosomes, Human, Y|Chromosome Deletion|Minor Histocompatibility Antigens|Fertility 104 ddx3y 31696986 J Gene Med 2019 10.1002/jgm.3137 0 3 0 71 Humans|TLR4 protein, human|*Toll-Like Receptor 4|*Smoke|*Epithelial Cells|*Tobacco|Bronchi|NF-kappa B|MicroRNAs|Signal Transduction|Smoking|Cell Line|DDX3Y protein, human|Minor Histocompatibility Antigens|DEAD-box RNA Helicases|MIRN497 microRNA, human 104 ddx3y 31205025 J. 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Reprod. 2019 10.1093/humrep/dez004 1 0 0 71 Male|Humans|Female|*Gonadoblastoma|*Dysgenesis, Gonadal|*Turner Syndrome|*Germ Cells|*Karyotypes|DNA-Binding Proteins|Y Chromosome, Human|Cell Cycle Proteins|*Karyotyping|Transcription Factors|Nuclear Proteins|Testicular Neoplasms|Sex-Determining Region Y Protein|Phenotype|Development, Sexual|Ovarian Neoplasms|Gonads|DDX3Y protein, human 104 ddx3y 30613052 J. Reprod. Dev. 2019 PMC6473106 10.1262/jrd.2018-145 1 0 0 71 Humans|Male|Animals|Mice|*Azoospermia|Spermatogenesis|*Germ Cells|Spermatozoa|Ddx3x protein, mouse|Testis|Transcription, Genetic|DEAD-box RNA Helicases|Chromosomes, Human, Y|Minor Histocompatibility Antigens|X Chromosome|Fertility|DDX3X protein, human|DDX3Y protein, human|D1Pas1 protein, mouse 104 DISP1 31808517 Biosci. Rep. 2019 PMC6928520 10.1042/BSR20191942 0 0 0 24 *Autism Spectrum Disorder|Gene Regulatory Networks|*Obsessive Compulsive Disorder|Gene Expression 34 DISP1 30838450 Hum. Genet. 2019 10.1007/s00439-019-01993-y 3 1 0 24 Humans|Mice|Animals|*Cell Polarity|Hedgehog Proteins|*Neural Tube Defect|Neural Tube|*Wnt Signaling Pathway|Mutation|Cohort Studies 34 DNAH11 31879361 J. Med. Genet. 2019 10.1136/jmedgenet-2019-106501 0 0 0 12 Kartagener Syndrome|Mutations|Cilia|Phenotype|*Cohort Studies 63 DNAH11 31765523 Pediatr. 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Genet. 2019 PMC6499982 10.1186/s12881-019-0796-9 0 0 0 12 Humans|*Esophageal Squamous Cell Carcinoma|*Prognosis|*Esophageal Neoplasms|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Asian Continental Ancestry Group|Genetic Predisposition to Disease|Carcinoma, Squamous Cell|*Introns|Genotype|Case-Control Studies|DNAH11 protein, human|Axonemal Dyneins|LRFN2 protein, human|Membrane Proteins 63 DNAH11 31040315 Sci Rep 2019 PMC6491566 10.1038/s41598-019-43109-6 0 0 0 12 Humans|*Heterotaxy Syndrome|Axonemal Dyneins|Heterozygote|Cilia|Mutation|DNAH11 protein, human 63 DNAH11 30947698 BMC Cancer 2019 PMC6449945 10.1186/s12885-019-5494-7 1 0 0 12 Humans|*Whole Exome Sequencing|Breast Cancer, Familial|*Breast Neoplasms|BRCA2 protein, human|*BRCA2 Protein|BRCA1 protein, human|*BRCA1 Protein|Fanconi Anemia Complementation Group N Protein|Germ-Line Mutation|Genetic Predisposition to Disease|Nuclear Proteins|Pedigree|Allele|DNA Repair 63 DNAI1 31772028 J. Med. Genet. 2019 10.1136/jmedgenet-2019-106424 0 0 0 22 *Genotype|Kartagener Syndrome|Cilia|Phenotype|Dyneins|Mutation|Microscopy, Video 64 DNAI1 31765523 Pediatr. Pulmonol. 2019 10.1002/ppul.24583 0 0 0 22 Humans|Turkey|*Phenotype|Kartagener Syndrome|*Genotype|Homozygote|Genetic Testing|Cilia|Mutation|Cytoskeletal Proteins 64 DNAI1 31628824 Basic Clin. Pharmacol. Toxicol. 2019 10.1111/bcpt.13342 0 0 0 22 Male|Animals|Rats|*Alcoholism|*Rats, Sprague-Dawley|*Hippocampus|Alcohol Drinking|*Gene Expression Profiling|Ethanol|*Microarray Analysis|Impairments, Cognitive|Oxidative Stress|Republic of Korea 64 DNAI1 31507630 Front Genet 2019 PMC6713718 10.3389/fgene.2019.00749 0 0 0 22 Humans|*Kartagener Syndrome|*Mutations|Axonemal Dyneins|Cilia|Heterozygote|Sequencing, Whole Exome|Genetic Heterogeneity|Heterotaxy Syndrome|Chinese 64 DNAI1 31068677 Cell Death Differ. 2019 PMC7224178 10.1038/s41418-019-0332-7 2 2 0 22 Male|Female|Animals|Mice|*RNA, Micro|*Gene Expression Regulation|Cilia|Nuclear Proteins|Tumor Protein p73|Cells, Epithelial|Cell Differentiation|Forkhead Transcription Factors|Cells, Cultured|Choroid Plexus|Epithelium|*Complement|FOXJ1 protein, mouse 64 DNAI1 30622330 Eur. J. Hum. Genet. 2019 PMC6460585 10.1038/s41431-018-0307-z 3 0 0 22 Humans|Animals|*Whole Exome Sequencing|Heterotaxy Syndrome|Zebrafish Proteins|Zebrafish|Body Patterning|Embryo, Nonmammalian|Phenotype|Pedigree|Mutation|Heterozygote|SMAD2 protein, human|Smad2 Protein|MMP21 protein, human|Matrix Metalloproteinases, Secreted|RAI2 protein, human|Proteins|Acvr2b protein, zebrafish 64 DNAI2 31666004 BMC Genomics 2019 PMC6822442 10.1186/s12864-019-6164-5 0 0 0 30 Humans|Swine|Animals|Male|*Genome-Wide Association Study|*Semen|*Phenotype|Quantitative Trait Loci|Semen Analysis|Sus scrofa|Sperm Motility|Genetic Association Studies|Genotype|Polymorphism, Single Nucleotide|Artificial Insemination|Genetic Selection|Pedigree|*Bodily Secretions 30 DNAI2 30935420 World J Surg Oncol 2019 PMC6444505 10.1186/s12957-019-1605-9 3 0 0 30 Humans|*Computational Biology|*Nasopharyngeal Carcinoma|*Transcription Factors|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Databases, Genetic|Protein Interaction Mapping|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor|Software|Nasopharyngeal Neoplasms 30 DRC1 31701675 Mol Genet Genomic Med 2019 PMC6978274 10.1002/mgg3.1033 1 1 0 38 Humans|*Homozygote|Japan|*Sequence Deletion|*Exons|Kartagener Syndrome|Cilia|Diffuse panbronchiolitis|Bronchiolitis|Haemophilus Infections|*Infections 45 DRC1 31659045 Proc. 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Cell Biol. 2019 10.1016/j.ceb.2019.10.006 0 2 0 52 Animals|*Cadherins|Drosophila Proteins|Cell Polarity|Drosophila melanogaster|Cell Adhesion Molecules|Wings, Animal|Gene Expression Regulation, Developmental|Signal Transduction|Microtubules|dachsous protein, Drosophila|Fat2 protein, Drosophila 58 FAT2 31037571 Transgenic Res. 2019 10.1007/s11248-019-00127-4 0 1 0 52 Humans|Animals|Swine|*Animals, Genetically Modified|*Polyunsaturated Fatty Acids|n 3 PUFA|Fatty Acids, Omega-6|Fatty Acid Desaturases|Fatty Acids|Linoleic Acid|Diet|FAT1 protein, human|Cadherins|FAT2 protein, human 58 FAT2 30827914 Curr. 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Chem. 2019 10.1373/clinchem.2019.305391 0 0 0 124 Humans|*Ribitol|*Dystrophy, Muscular|D-ribitol-5-phosphate cytidylyltransferase|*Nucleotidyltransferases|cytidine diphosphate ribitol|*Nucleoside Diphosphate Sugars|Dystroglycans|Glycosylation|Pentosyltransferases|HEK293 Cells|Cytidine Diphosphate 146 FKTN 31066050 Ann. Hum. Genet. 2019 10.1111/ahg.12319 0 0 0 124 *Muscular Dystrophies, Limb Girdle|*Sequencing, Next-Generation|Sequence Analysis, DNA|Mutation 146 FKTN 30980196 Int. J. Clin. Oncol. 2019 10.1007/s10147-019-01443-9 0 3 0 124 Humans|*Stomach Neoplasms|MUC1 protein, human|*Mucin-1|*Cancer Stem Cells|*Phenotype|Gene Expression Regulation, Neoplastic|DNA Methylation|Prognosis|Mucin, Gastric|Stomach|Mucin 5AC|Spheroid, Cellular|Genes, CDKN2A|Carcinogenesis 146 frem1 31563616 Neurochirurgie 2019 10.1016/j.neuchi.2019.09.010 0 0 0 54 Mice|Animals|*Craniosynostosis|Acrocephalosyndactylia|Receptor, Fibroblast Growth Factor, Type 2|Twist-Related Protein 1|Receptor, Fibroblast Growth Factor, Type 3|Nuclear Proteins|Phenotype|Mutation|*Animal Models 58 frem1 30873160 Front Immunol 2019 PMC6403165 10.3389/fimmu.2019.00272 0 22 0 54 Humans|*Toll-Like Receptor 1|Sex Workers|*Inflammation|Toll-Like Receptor|Signal Transduction|*Interleukin|Receptor, Interleukin 1|TILRR protein, human|Receptors, Interleukin 58 FRMD7 31743612 Brain Behav 2019 PMC6908866 10.1002/brb3.1473 1 1 0 40 Animals|Mice|Humans|*Neurites|X-Linked Infantile Nystagmus|Congenital Nystagmus|Genetic Diseases, X-Linked|Cytoskeletal Proteins|*Nystagmus, Pathologic|Membrane Proteins|Mutations|*Neurons|Pedigree|Asian Continental Ancestry Group|FRMD7 protein, human|FRMD7 protein, mouse 79 FRMD7 31495972 J. Clin. Lab. Anal. 2019 PMC6977136 10.1002/jcla.23012 1 0 0 40 Humans|X-Linked Infantile Nystagmus|Quality of Life|*Nystagmus, Congenital|*Genetic Diseases, X-Linked|*Frameshift Mutation|Cytoskeletal Proteins|*Sequencing, Next-Generation|Mutations|Membrane Proteins|*Chinese|Pedigree|Mutation, Missense|Heterogeneities, Genetic|GPR143 protein, human|Eye Proteins|Membrane Glycoproteins|FRMD7 protein, human 79 FRMD7 31291246 PLoS ONE 2019 PMC6619597 10.1371/journal.pone.0213702 1 0 0 40 Animals|Mice|*Sequencing, RNA|*Transcriptome Profiling|Molecular Sequence Annotation|*Lung|Transcription Factor|*Base Sequence|*Whole Exome Sequencing|Transcriptome|Gene Expression Regulation, Developmental|Nuclear Proteins|Transcription, Genetic|Mice, Knockout|Organogenesis|Signal Transduction|IGF1 protein, human|IGF-1|Brain|RNA 79 FRMD7 30942644 Ophthalmic Genet. 2019 10.1080/13816810.2019.1592201 0 0 0 40 *Nystagmus, Congenital|*Albinism, Ocular|Genetic Diseases, X-Linked|Cytoskeletal Proteins|Eye Proteins|Pedigree|Membrane Proteins|Genes, X-Linked|Mutation|Membrane Glycoproteins 79 FRMD7 30890130 BMC Med. Genet. 2019 PMC6423883 10.1186/s12881-019-0780-4 0 0 0 40 Humans|*Nystagmus, Congenital|*Genes, X-Linked|*Chinese|*Cataract|DNA Mutational Analysis|Pedigree|Genetic Diseases, X-Linked|Base Sequence|Cytoskeletal Proteins|Membrane Proteins|Mutation|Amino Acid Sequence 79 FRMD7 30670464 EMBO Mol Med 2019 PMC6404109 10.15252/emmm.201810218 0 0 0 40 *Vision|Blindness|cis-trans-Isomerases|Retina|Retinal Diseases|Eye Proteins|Genetic Therapy 79 FRMD7 30618027 J. Mol. Neurosci. 2019 10.1007/s12031-018-1245-5 1 0 0 40 Pregnancy|Male|Humans|Female|Nystagmus, Congenital|*Chinese|Genetic Diseases, X-Linked|Cytoskeletal Proteins|DNA Mutational Analysis|Heterozygote|Pedigree|Base Sequence|Membrane Proteins|Genes, X-Linked|Mutation|Phenotypes|FRMD7 protein, human 79 FRMD7 30616528 BMC Med. Genet. 2019 PMC6323710 10.1186/s12881-018-0720-8 1 0 0 40 Humans|X-Linked Infantile Nystagmus|*Frameshift Mutation|*Nystagmus, Congenital|*Genetic Diseases, X-Linked|*Chinese|DNA Mutational Analysis|Cytoskeletal Proteins|Mutation|Pedigree|X-Linked Inheritance|Base Sequence|Membrane Proteins|FRMD7 protein, human 79 FSCN2 31837603 Mol Ther Nucleic Acids 2019 PMC6920229 10.1016/j.omtn.2019.11.006 0 0 0 24 *Myocytes, Cardiac|AGO2 protein, human|Argonaute Proteins|MicroRNAs|*RNA, Untranslated|Gene Expression Regulation|RNA, Messenger|Upregulation|Downregulation|Promoter Regions, Genetic|Chromatin 34 FSCN2 31654038 Eur. J. Hum. Genet. 2019 PMC7080750 10.1038/s41431-019-0531-1 1 0 0 24 Humans|*RNA Splicing|Retinitis Pigmentosa|*Retina|Pre-mRNA|Eye Proteins|Genes, Dominant|Intron|*Phototransduction|Carrier Proteins|Mutation|PRPF31 protein, human 34 FSCN2 31019967 Biomed Res Int 2019 PMC6451803 10.1155/2019/3526407 3 0 0 24 Humans|*RNA, Long Noncoding|*miRNA|*mRNA|*Cholangiocarcinoma|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Prognosis|Biomarkers, Tumor|Gene Ontology|Computational Biology|Kaplan-Meier Estimate|Bile Duct Neoplasms|Bile Ducts, Intrahepatic 34 FUCA1 31886074 Cureus 2019 PMC6907717 10.7759/cureus.6139 0 0 0 69 Humans|Female|*Fucosidosis|Quality of Life|alpha-L-Fucosidase|Mutation 69 FUCA1 31603145 Med. Sci. Monit. 2019 PMC6800466 10.12659/MSM.915876 0 0 0 69 Humans|Female|Pregnancy|Mucolipidosis 2|Mucolipidoses|*Lysosomal Storage Diseases|Phenotype|Fucosidosis|Transferases (Other Substituted Phosphate Groups)|Mutation|Genotype|Pedigree|Lysosomes|Chinese|Sequencing, Next-Generation|GNPTAB protein, human 69 FUCA1 31419081 Int J Rheum Dis 2019 10.1111/1756-185X.13639 0 0 0 69 Adult|Child|Humans|*alpha-L-Fucosidase|Sjogren's Syndrome|Autoimmune Diseases|Antibodies, Antinuclear|*Rheumatic Diseases|Biomarkers 69 FUCA1 31353672 Mol. Reprod. Dev. 2019 10.1002/mrd.23243 0 1 0 69 Pregnancy|Humans|Cattle|Animals|Horses|Female|*Gonadotropins, Equine|*Fallopian Tubes|*Oviduct|Chorionic Gonadotropin|Follicle Stimulating Hormone|Messenger RNA|Oestradiol|Progesterone|Gene Expression|FUCA2 protein, human|alpha-L-Fucosidase 69 FUCA1 31064022 Neuropediatrics 2019 10.1055/s-0039-1684052 1 0 0 69 *Fucosidosis|*Homozygote|*Dystonia|alpha-L-Fucosidase|*Dystonic Disorders|Mutations|Pedigree 69 FUCA1 30729618 Pathol. Int. 2019 10.1111/pin.12764 0 0 0 69 *Carcinoma, Mucoepidermoid|*Squamous Cell Carcinoma|*alpha-L-Fucosidase|Mouth Neoplasms|Salivary Gland Neoplasms|Head and Neck Neoplasms|Minor Salivary Glands|TP53 protein, human|Tumor Suppressor Protein p53|Salivary Glands|Biomarkers, Tumor|Fucose 69 GDAP1 31852984 J. Hum. Genet. 2019 10.1038/s10038-019-0710-5 0 0 0 407 Humans|*Charcot-Marie-Tooth Disease|*DNA Copy Number Variations|Comparative Genomic Hybridization|Hereditary Sensory and Motor Neuropathy|Exome|Sequencing, Next-Generation|Mutations|Phenotype|Cohort Studies|LRSAM1 protein, human|Ubiquitin-Protein Ligases 170 GDAP1 31827005 Neurology 2019 PMC7011687 10.1212/WNL.0000000000008672 0 0 0 407 *Charcot-Marie-Tooth Disease|Myelin P0 Protein|*Sequencing, Next-Generation|Genetic Testing|Connexins|Gene Duplication|Genotype|Gene Deletion|Demyelinating Diseases 170 GDAP1 31655048 Exp. Neurol. 2019 10.1016/j.expneurol.2019.113069 3 0 0 407 Charcot-Marie-Tooth disease, Type 2K|*Charcot-Marie-Tooth Disease|Mutation|Axons|Nerve Tissue Proteins|Electron Transport Complex I|Phenotype|*Oxidation-Reduction|Mitochondria|Oxidative Stress 170 GDAP1 31468327 Neuromolecular Med. 2019 10.1007/s12017-019-08564-4 0 0 0 407 Humans|Charcot-Marie-Tooth disease, Type 2C|Hereditary Motor And Sensory Neuropathy, Type IIC|*Charcot-Marie-Tooth Disease|TRPV4 protein, human|*TRPV Cation Channels|*Incidence|Mutations|Spinal Muscular Atrophy, Scapuloperoneal|Phenotype|Pedigree|Osteochondrodysplasias|Exons|*Cohort Studies|Diabetes Mellitus, Type 2|Europe|Australia 170 GDAP1 31271761 Exp. Neurol. 2019 10.1016/j.expneurol.2019.113004 1 0 0 407 *Charcot-Marie-Tooth Disease|*Axons|Nerve Tissue Proteins|Mitochondria|Mutations 170 GDAP1 31179332 Biomed Res Int 2019 PMC6507255 10.1155/2019/7132494 0 0 0 407 Charcot-Marie-Tooth Disease|Genes, Recessive|Pedigree|Mutations|Phenotype|Nerve Tissue Proteins 170 GDAP1 30804591 J Pak Med Assoc 2019 0 0 0 407 Humans|*Polymorphism, Single Nucleotide|Charcot-Marie-Tooth disease, Type 2K|*Charcot-Marie-Tooth Disease|Phenotype|Nerve Tissue Proteins|Mutation|Pedigree|Membrane Proteins|Modifier Gene|Genetic Susceptibility|Age of Onset|Severity of Illness Index 170 GDAP1 30692068 Nan Fang Yi Ke Da Xue Xue Bao 2019 PMC6765573 10.12122/j.issn.1673-4254.2019.01.10 0 0 0 407 Charcot Marie Tooth Disease|Pedigree|Genes, Dominant|Phenotype|Nerve Tissue Proteins|Mutation 170 GNPTG 31795562 Zhonghua Er Ke Za Zhi 2019 10.3760/cma.j.issn.0578-1310.2019.12.010 0 0 0 56 50 GNPTG 31669185 Prog. Neurobiol. 2019 PMC6938554 10.1016/j.pneurobio.2019.101718 1 0 0 56 Humans|*Stuttering|*Intermediate Filaments|Speech|Transferases (Other Substituted Phosphate Groups)|Brain|Mutations|mannose-6-phosphate|Mannosephosphates|*Lysosomes|Phosphoric Diester Hydrolases|Magnetic Resonance Imaging|GNPTG protein, human 50 GNPTG 31003007 J Commun Disord 2019 10.1016/j.jcomdis.2019.03.007 0 0 0 56 Humans|*Stuttering|Transferases (Other Substituted Phosphate Groups)|*Complement Factor B|3'-(1-butylphosphoryl)adenosine|Mutation|Phosphoric Diester Hydrolases 50 GNPTG 30882951 Hum. Mutat. 2019 10.1002/humu.23748 3 0 0 56 Child, Preschool|Humans|Child|*Mucolipidoses|Transferases (Other Substituted Phosphate Groups)|*Mutations|*Lysosomal Storage Diseases|Mutations, Missense|Phenotype|Genotype-Phenotype Correlations|Lysosomes|*Gamma Rays|GNPTG protein, human|GNPTAB protein, human 50 GSDMC 31628657 Adv. Exp. Med. Biol. 2019 10.1007/978-981-13-9367-9_9 2 0 0 11 Humans|Mice|Animals|*Pyroptosis|Caspases|Inflammasomes|Neoplasm Proteins|Cell Death|Cardiolipin|Proteolysis|Phosphatidylinositol Phosphates|Serine, Phosphatidyl|Protein Processing, Post-Translational|GSDMA protein, human|GSDMD protein, human 19 GSDMC 31455540 Meth. Enzymol. 2019 10.1016/bs.mie.2019.04.024 0 0 0 11 Humans|Animals|Pyroptosis|Caspases|Inflammasome|Neoplasm Proteins|Cell Membranes|Cell Death|Cytokines|Inflammation|Liposome|GSDMA protein, human|GSDMD protein, human 19 HEPACAM 31494281 Neurobiol. Dis. 2019 10.1016/j.nbd.2019.104603 0 0 0 129 Animals|Mice|*Alzheimer Disease|Amyloid beta-Peptides|*Proteome|Proteomics|Neurodegenerative Diseases|Amyloid beta-Protein Precursor|Plaque, Amyloid|*Disease Models, Animal|*Hippocampus|Mice, Transgenic|Memory Loss 70 HEPACAM 31372844 World J Pediatr 2019 PMC6785595 10.1007/s12519-019-00284-w 1 0 0 129 Humans|Animals|Mice|Megalencephalic leukoencephalopathy with subcortical cysts|Hereditary Central Nervous System Demyelinating Diseases|*Cysts|*Megalencephaly|*Mutations|*Brain|Membrane Proteins|Cell Cycle Proteins|*Chinese|Imaging, Magnetic Resonance|*Disease Models, Animal|*Nervous System Malformations|Mlc1 protein, mouse|GlialCAM protein, mouse|Nerve Tissue Proteins|Cell Adhesion Molecules, Neuron-Glia 70 HEPACAM 30664187 Mol Med Rep 2019 PMC6390061 10.3892/mmr.2019.9841 0 22 0 129 Humans|Male|AR protein, human|*Receptors, Androgen|*Prostate Cancer|*Cell Proliferation|Prostate|Androgens|Cell Movement|Cell Line, Tumor|*Protein Transport|Gene Expression Regulation, Neoplastic|Downregulation|Cell Nucleus|*Hepatocyte|Proteins|HEPACAM protein, human 70 HPS3 31880485 Platelets 2019 10.1080/09537104.2019.1704716 0 0 0 43 Humans|*Hermanski-Pudlak Syndrome|Pedigree|Phenotype|Mutation|HPS3 protein, human|Carrier Proteins 51 HPS3 31619213 BMC Pulm Med 2019 PMC6794755 10.1186/s12890-019-0941-4 0 0 0 43 *Hermanski-Pudlak Syndrome|*Pulmonary Fibrosis|Phenotype|Mutation|Pedigree|Membrane Proteins|*Disease Progression 51 HPS3 31611645 Nat Microbiol 2019 10.1038/s41564-019-0580-9 0 0 0 43 Humans|*Vacuoles|Salmonella typhimurium|Salmonella Infections|Virulence|Bacterial Proteins|*Biological Transport|Host-Pathogen Interactions|Protein Transport|HeLa Cells 51 HPS3 31331193 Circulation 2019 PMC6749971 10.1161/CIRCULATIONAHA.119.041546 2 0 0 43 Humans|anacetrapib|*Oxazolidinones|Cholesterol Ester Transfer Proteins|Anticholesteremic Agents|Cholesterol, LDL|*Genotype|adenylate cyclase 9|*Adenylyl Cyclases|Atherosclerosis|Efficacy, Clinical|Cardiovascular Diseases 51 HPS3 31141302 Pigment Cell Melanoma Res 2019 10.1111/pcmr.12800 0 0 0 43 Humans|Japan|Oculocutaneous albinism type 1|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|Hermanski-Pudlak Syndrome|*Sequencing, Next-Generation|*Albinism|Mutation|Phenotype|Genetic Predisposition|Asian Continental Ancestry Group|Pedigree|Heterozygote|Membrane Transport Proteins|HPS3 protein, human|Carrier Proteins 51 HPS3 30990103 Ann. Med. 2019 10.1080/07853890.2019.1587498 0 0 0 43 51 HPS6 31619213 BMC Pulm Med 2019 PMC6794755 10.1186/s12890-019-0941-4 0 0 0 1552 *Hermanski-Pudlak Syndrome|*Pulmonary Fibrosis|Phenotype|Mutation|Pedigree|Membrane Proteins|*Disease Progression 44 HPS6 31249973 TH Open 2019 PMC6524924 10.1055/s-0038-1676813 3 0 0 1552 Humans|Platelet Disorder, Undefined|*Blood Platelet Disorders|*Sequencing, Next-Generation|*Hemorrhagic Disorders|Exome|*Blood Coagulation Disorders|Genetic Predisposition to Disease|Bleeding|Databases, Genetic|Cohort Studies 44 HPS6 31141302 Pigment Cell Melanoma Res 2019 10.1111/pcmr.12800 0 0 0 1552 Humans|Japan|Oculocutaneous albinism type 1|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|Hermanski-Pudlak Syndrome|*Sequencing, Next-Generation|*Albinism|Mutation|Phenotype|Genetic Predisposition|Asian Continental Ancestry Group|Pedigree|Heterozygote|Membrane Transport Proteins|HPS3 protein, human|Carrier Proteins 44 HPS6 30990103 Ann. Med. 2019 10.1080/07853890.2019.1587498 0 0 0 1552 44 HPS6 30947698 BMC Cancer 2019 PMC6449945 10.1186/s12885-019-5494-7 1 0 0 1552 Humans|*Whole Exome Sequencing|Breast Cancer, Familial|*Breast Neoplasms|BRCA2 protein, human|*BRCA2 Protein|BRCA1 protein, human|*BRCA1 Protein|Fanconi Anemia Complementation Group N Protein|Germ-Line Mutation|Genetic Predisposition to Disease|Nuclear Proteins|Pedigree|Allele|DNA Repair 44 HPS6 30710063 Biosci. Rep. 2019 PMC6379572 10.1042/BSR20182339 0 0 0 1552 Mice|Animals|*Hermanski-Pudlak Syndrome|*Lipids|*Lipidomics|Phenotypes|Mice, Inbred C57BL|Membrane Proteins|*Atherosclerosis|Mutation|*Plasma|Disease Models, Animal 44 hydin 31765523 Pediatr. Pulmonol. 2019 10.1002/ppul.24583 0 0 0 24 Humans|Turkey|*Phenotype|Kartagener Syndrome|*Genotype|Homozygote|Genetic Testing|Cilia|Mutation|Cytoskeletal Proteins 49 hydin 31545650 Am. J. Respir. Cell Mol. Biol. 2019 10.1165/rcmb.2019-0086OC 2 1 0 24 Humans|Kartagener Syndrome|Axoneme|Cilia|Mutations|Transmission Electron Microscopy 49 hydin 31397435 Mol. Biol. (Mosk.) 2019 10.1134/S0026898419040141 0 0 0 24 Paraganglioma|*Head and Neck Neoplasms|Succinate Dehydrogenase|Sequencing, Whole Exome|*Paraganglioma, Extra-Adrenal|Mutation|Genetic Predisposition to Disease 49 hydin 30810461 Epigenetics 2019 PMC6557555 10.1080/15592294.2019.1582217 3 0 0 24 Male|Adult|Cattle|Mice|Humans|Animals|*Epigenomics|*Multifactorial Inheritance|Genome-Wide Association Study|*Epigenome|*Sperm|DNA Methylation|CpG Islands|Epigenesis, Genetic|Promoter Regions, Genetic|Mammals|Fertility|Transcriptome|Embryo Development 49 hydin 30622330 Eur. J. Hum. Genet. 2019 PMC6460585 10.1038/s41431-018-0307-z 3 0 0 24 Humans|Animals|*Whole Exome Sequencing|Heterotaxy Syndrome|Zebrafish Proteins|Zebrafish|Body Patterning|Embryo, Nonmammalian|Phenotype|Pedigree|Mutation|Heterozygote|SMAD2 protein, human|Smad2 Protein|MMP21 protein, human|Matrix Metalloproteinases, Secreted|RAI2 protein, human|Proteins|Acvr2b protein, zebrafish 49 IFNE 31734130 Semin. Immunol. 2019 10.1016/j.smim.2019.101328 1 0 0 58 Female|*Type I Interferon|STAT Transcription Factors|Janus Kinases|Receptor, Interferon alpha-beta|Transductions, Signal|Interferon-alpha|Protein Binding|Cytokines 19 IFNE 31630191 Carcinogenesis 2019 PMC7298620 10.1093/carcin/bgz173 1 0 0 58 Genome-Wide Association Study|*Melanoma|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Skin Neoplasms|Genes, p16|Quantitative Trait Loci|Chromatin 19 IFNE 31520463 Mol Oral Microbiol 2019 PMC7362904 10.1111/omi.12270 1 1 0 58 *Type I Interferon|*Antiviral Agents|IRF3 protein, human|Interferon Regulatory Factor-3|Infection, Viral|Viruses|Immunity, Innate|*Cells, Epithelial|Virus Replication|*Gene Expression|Signal Transduction 19 IFNE 31490936 PLoS ONE 2019 PMC6730848 10.1371/journal.pone.0213880 0 1 0 58 Humans|Animals|*Camelus|*MCF-7 Cells|Cloning, Molecular|cDNA|Sequence Alignment|Amino Acid Sequence|Base Sequence|Recombinant Proteins|Sequence Homology, Amino Acid|Escherichia coli|Phylogeny|Models, Molecular|Open Reading Frame|Interferons 19 IFNE 30743107 Theriogenology 2019 10.1016/j.theriogenology.2019.01.028 0 0 0 58 Pregnancy|Horses|Animals|Female|Male|*Endometrium|Progesterone|Estrus|Pregnancy, Animal|Ovulation|Embryo, Mammalian|*Gene Expression Regulation|Fertility 19 IFNK 31869529 Cancer Med 2019 PMC7013077 10.1002/cam4.2804 1 0 0 71 Humans|*Toll-Like Receptor 3|MB21D1 protein, human|*Nucleotidyltransferases|*Signal Transduction|*Colorectal Cancer|Interferon Regulatory Factor-3|Protein-Serine-Threonine Kinases|Membrane Proteins|*Colonic Neoplasms|*Chromogranin A|Cohort Studies|TLR3 protein, human|TBK1 protein, human 19 IFNK 31819584 Clin Cosmet Investig Dermatol 2019 PMC6890215 10.2147/CCID.S218243 0 5 0 71 Humans|interferon kappa|*Cytokines|*Psoriasis|Type I Interferon|Keratinocytes|*Up-Regulation|Skin|Epidermis|Dermatitis, Atopic|Interferon-gamma|*Transcriptional Activation|Cells, Cultured 19 IFNK 31666385 J. Virol. 2019 PMC6955282 10.1128/JVI.01582-19 3 1 0 71 Humans|*HPV 16|Oncogene Proteins, Viral|Keratinocytes|Papillomaviridae|Papillomavirus Infections|Signal Transduction|*Episomes|Interferon|Cell Differentiation 19 IFNK 31520463 Mol Oral Microbiol 2019 PMC7362904 10.1111/omi.12270 1 1 0 71 *Type I Interferon|*Antiviral Agents|IRF3 protein, human|Interferon Regulatory Factor-3|Infection, Viral|Viruses|Immunity, Innate|*Cells, Epithelial|Virus Replication|*Gene Expression|Signal Transduction 19 IGHMBP2 31827005 Neurology 2019 PMC7011687 10.1212/WNL.0000000000008672 0 0 0 49 *Charcot-Marie-Tooth Disease|Myelin P0 Protein|*Sequencing, Next-Generation|Genetic Testing|Connexins|Gene Duplication|Genotype|Gene Deletion|Demyelinating Diseases 118 IGHMBP2 31802621 J. Cell. Mol. Med. 2019 PMC6991628 10.1111/jcmm.14874 1 0 0 49 Humans|Infant, Newborn|Spinal muscular atrophy with respiratory distress 1|*Muscular Atrophy, Spinal|*Respiratory Distress Syndrome, Newborn|DNA-Binding Proteins|Transcription Factors|*Phenotypes|Mutations|Respiration Disorders|Gene Therapy|IGHMBP2 protein, human 118 IGHMBP2 31604525 Biochem. Biophys. Res. Commun. 2019 PMC6936219 10.1016/j.bbrc.2019.10.032 0 0 0 49 Humans|Infant, Newborn|Mice|Animals|Spinal muscular atrophy with respiratory distress 1|*Mice, Inbred C57BL|*Muscular Atrophy, Spinal|Respiratory Distress Syndrome, Newborn|DNA-Binding Proteins|Transcription Factors|*Disease Models, Animal|Motor Neurons, Alpha|*Mice, Inbred Strains|Muscle Atrophy|Gene Expression|Phenotype|IGHMBP2 protein, human 118 IGHMBP2 31445043 Exp. Neurol. 2019 10.1016/j.expneurol.2019.113041 1 0 0 49 Mice|Infant, Newborn|Animals|Humans|Spinal muscular atrophy with respiratory distress 1|*Induced Pluripotent Stem Cells|*Muscular Atrophy, Spinal|Respiratory Distress Syndrome, Newborn|*Neural Stem Cell|Motor Neurons|*Disease Models, Animal|*Phenotype|Stem Cell Transplantation|DNA-Binding Proteins|Spinal Cord|IGHMBP2 protein, human|Transcription Factors 118 IGHMBP2 31020813 Mol Genet Genomic Med 2019 PMC6565564 10.1002/mgg3.676 2 1 0 49 *Splice Site, Cryptic|*Charcot Marie Tooth Disease|*Phenotype|Pedigree|*Sequencing, Whole Genome|Transcription Factors|Mutation 118 IGHMBP2 30863264 J. Korean Med. Sci. 2019 PMC6406039 10.3346/jkms.2019.34.e54 0 1 0 49 Infant|Infant, Newborn|Humans|Spinal muscular atrophy with respiratory distress 1|*Exome|Syria|*Muscular Atrophy, Spinal|Respiratory Distress Syndrome, Newborn|DNA-Binding Proteins|Transcription Factors|*Whole Exome Sequencing|Mutation|*Databases, Genetic|*Dyspnea|*Infant Deaths 118 IGHMBP2 30598237 Neuromuscul. Disord. 2019 10.1016/j.nmd.2018.10.002 2 0 0 49 Infant, Newborn|Humans|Child|Infant|Spinal muscular atrophy with respiratory distress 1|*Retrospective Studies|*Muscular Atrophy, Spinal|*Respiratory Distress Syndrome, Newborn|DNA-Binding Proteins|Transcription Factors|Mutations|Paralysis, Diaphragmatic|Phenotype|Muscle Weakness|Respiration, Artificial|Prognosis 118 IGSF9 31235647 J. Neurosci. 2019 PMC6733566 10.1523/JNEUROSCI.0075-19.2019 0 0 0 96 Animals|*Axonal Transport|*Color Vision|Synaptic Vesicle|Presynaptic Terminals|Synaptic Transmission|Drosophila|Nerve Tissue Proteins|Membrane Proteins|Animals, Genetically Modified|Neurogenesis|Protein Transport|borderless protein, Drosophila 19 IGSF9 31118890 Front Cell Neurosci 2019 PMC6504704 10.3389/fncel.2019.00183 0 0 0 96 Animals|*Depression|Purkinje Neuron|Synapses|Cerebellum|Neurons|Dendrites|Excitatory Postsynaptic Potentials|Nerve Fibers|Long-Term Potentiation|*Axons|Synaptic Plasticity|Animals, Newborn 19 IMPG2 31694913 J. Biol. Chem. 2019 PMC6916492 10.1074/jbc.RA119.009712 0 0 0 17 *Photoreceptor Cells|Retinal Degeneration|Cilia|Neoplasm Proteins|Antigens, Neoplasm|Nuclear Proteins|Retina|Mutations|*Myosins 26 IMPG2 31264916 Ophthalmic Genet. 2019 10.1080/13816810.2019.1627467 1 0 0 17 26 IRX2 31599112 FEBS J. 2019 10.1111/febs.15086 0 1 0 141 Humans|*DNA Methylation|CpG Islands|histone H3 trimethyl Lys4|Histones|*Leukemia, Myeloid, Acute|Epigenesis, Genetic|Chromatin|Promoter Regions, Genetic|*Protein Processing, Post-Translational|Genes, Tumor Suppressor|Oligonucleotide Array Sequence Analysis|Sequence Analysis, DNA|DNA 71 IRX2 31285354 Development 2019 10.1242/dev.177121 0 0 0 141 Animals|*Ventricular Septum|*Lizards|Cardiac Ventricle|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Biological Evolution 71 IRX2 30862593 World Neurosurg 2019 10.1016/j.wneu.2019.02.184 0 0 0 141 Female|Adolescent|Humans|*Scoliosis|*Kyphosis|Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genotype|Alleles|Case-Control Studies 71 IRX2 30760827 Sci Rep 2019 PMC6374403 10.1038/s41598-018-38315-7 1 0 0 141 Female|Humans|*Uterine Cervical Neoplasms|DNA Copy Number Variations|*Hexachlorobenzene|Sequencing, Whole Exome|BRCA2 protein, human|BRCA2 Protein|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Mutation|Biomarkers, Tumor|Cell Line, Tumor|Phenotype|Brazil|MAPK7 protein, human|Mitogen-Activated Protein Kinase 7 71 jph2 31810440 Mol. Med. 2019 PMC6898920 10.1186/s10020-019-0120-3 0 2 0 218 Female|Rats|Animals|*Triiodothyronine|*Rats, Sprague-Dawley|*Heart Failure|*Sarcolemma|Myocardial Infarction|Myocardial Contraction|Cardiomyocyte|Ventricular Remodeling|Heart Ventricles|Calcium Signaling|Echocardiography|RyR2|junctophilin|Membrane Proteins|Hemodynamic 52 jph2 31673803 Basic Res. Cardiol. 2019 10.1007/s00395-019-0758-6 3 0 0 218 Mice|Animals|*Myocytes, Cardiac|*Glucocorticoids|*Up-Regulation|Ryanodine Receptors|*Heart Ventricles|Glucocorticoid Receptor|Dexamethasone|*Autophagy|Calcium Signaling|Heart Failure|Myocardium|*Transcriptional Activation 52 jph2 31591206 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6815135 10.1073/pnas.1911304116 2 0 0 218 *Ryanodine Receptor Calcium Release Channel|junctophilin|*Muscle, Smooth, Vascular|*Membrane Proteins|*Smooth Muscle Cells|Calcium Signaling|*Muscle Contraction|Cerebral Arteries|Plasma Membrane 52 jph2 31478477 Acta Clin Belg 2019 10.1080/17843286.2019.1662572 0 0 0 218 Humans|Male|Aged, 80 and over|junctophilin|*Diagnosis, Differential|*Cardiomyopathy, Hypertrophic|*Cardiomyopathy|*Amyloidosis|*Membrane Proteins|Myocardium|Immunoglobulin Light-chain Amyloidosis|Echocardiography|Imaging, Magnetic Resonance|Biopsy|Diabetes Mellitus, Type 2 52 jph2 31337710 J. Biol. Chem. 2019 PMC6737222 10.1074/jbc.RA118.006772 1 1 0 218 junctophilin|Membrane Proteins|Sarcoplasmic Reticulum|Plasma Membranes|Ryanodine Receptor Calcium Release Channel|Endoplasmic Reticulum|Protein Domains|Palmitic Acid 52 jph2 31315980 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6681751 10.1073/pnas.1820980116 0 0 0 218 junctophilin|*Membrane Proteins|*Skeletal Muscle Fibers|Sarcoplasmic Reticulum|Muscle Proteins|Skeletal Muscles|Sarcolemma|Muscle Contraction|Triad resin|*Acrylic Resins|Calcium|Protein Domains 52 jph2 31227780 Sci Rep 2019 PMC6588559 10.1038/s41598-019-44987-6 2 0 0 218 Humans|Child|Infant, Newborn|junctophilin|*Cardiomyopathy, Dilated|Iran|*Membrane Proteins|*Homozygote|Cardiomyopathy, Hypertrophic|Muscle Proteins|Heterozygote|Cardiomyocyte|Cardiac Failure|Calcium Signaling|Intercellular Junctions|Mutation, Missense|Sequencing, Whole Exome|Cardiac Disease|Middle East 52 jph2 30867288 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6442575 10.1073/pnas.1822176116 6 0 0 218 Animals|*Heart Failure|Cardiomegaly|Excitation Contraction Coupling|Myocytes, Cardiac|Muscle Proteins|Calcium Signaling|MicroRNAs|Membrane Proteins|Disease Models, Animal 52 jph2 30681346 Circ Genom Precis Med 2019 PMC6410971 10.1161/CIRCGEN.119.002460 11 0 0 218 Humans|Cardiomyopathy, Hypertrophic, Familial|Cardiac Myosins|Cardiomyopathy, Hypertrophic|Myosin Heavy Chains|Genetic Testing|Sarcomeres|Mutation|Troponin T|Carrier Proteins 52 KCNJ13 31647904 Exp. Eye Res. 2019 PMC6899441 10.1016/j.exer.2019.107852 0 0 0 30 Animals|Humans|*Zebrafish|*Protein Domains|Snowflake vitreoretinal degeneration|Retinal Degeneration|Leber Congenital Amaurosis|Retina|*Membrane Proteins|Fluorescein Angiography|Coherence Tomography, Optical|Mutations|Homozygote|Eye Proteins|Fundus Oculi|Pedigree|Phenotype|Potassium Channels, Inwardly Rectifying 40 KCNJ13 30846767 Sci Rep 2019 PMC6405871 10.1038/s41598-019-40507-8 2 1 0 30 Snowflake vitreoretinal degeneration|Retinal Degeneration|Leber Congenital Amaurosis|Retina|Electroretinography|Retinal Pigment Epithelium|Potassium Channels, Inwardly Rectifying|*Phagosomes|Mutations|Phenotype 40 KCNJ13 30686507 Am. J. Hum. Genet. 2019 PMC6369573 10.1016/j.ajhg.2018.12.019 2 0 0 30 Humans|Child|*Retinal Pigment Epithelium|*Channelopathies|*Induced Pluripotent Stem Cells|Leber Congenital Amaurosis|Potassium Channels, Inwardly Rectifying|*Eye Abnormalities|*Vision Disorders|Homozygote|Blindness 40 KCNT1 31872048 Neurol Genet 2019 PMC6878841 10.1212/NXG.0000000000000363 1 0 0 42 *Epilepsy|*Focal Seizures|Epilepsies, Partial|*Mutation|Electroencephalography|Quinidine|Potassium Channels|Nerve Tissue Proteins|*Phenotypic Variability|Potassium Channels, Sodium-Activated|Phenotype 123 KCNT1 31835056 Seizure 2019 10.1016/j.seizure.2019.11.009 0 0 0 42 Humans|*Epilepsy, Reflex|Epilepsies, Partial|Mutations|Epilepsy Syndrome|Pedigree|GTPase-Activating Proteins|Tumor Suppressor Proteins|Repressor Proteins|Cohort Studies 123 KCNT1 31831960 Bioinformation 2019 PMC6900328 10.6026/97320630015772 0 0 0 42 *Cancer|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor 123 KCNT1 31812952 Aging (Albany NY) 2019 PMC6932877 10.18632/aging.102553 1 0 0 42 Humans|Animals|Auditory Nerve|Inner Hair Cell|Auditory Threshold|Hearing Loss, Noise-Induced|Evoked Potentials, Auditory, Brain Stem|Noise|Synapses|Neurons 123 KIAA0586 31816441 Eur J Med Genet 2019 10.1016/j.ejmg.2019.103823 0 0 0 86 Male|Humans|Child, Preschool|Jeune syndrome|*Ellis-Van Creveld Syndrome|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|Eye Abnormalities|Ciliopathies|Abnormalities, Multiple|Cytoplasmic Dyneins|Mutation|Pedigree|Cilia|Homozygote|Cerebellum|Retina|Proteins|DYNC2H1 protein, human 27 KIAA0586 31326647 Curr. Opin. Genet. Dev. 2019 10.1016/j.gde.2019.06.010 1 0 0 86 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Ciliopathy|Cilia|Cell Cycle Proteins|Mutation|Talpid3 protein, human 27 KIAA0586 30993914 Mol Genet Genomic Med 2019 PMC6565585 10.1002/mgg3.690 1 1 0 86 Humans|Child, Preschool|Child|*Whole Exome Sequencing|Polydactyly preaxial type 1|*Polydactyly|*Thumb|Zinc Finger Protein Gli3|Toes|Fingers|Pedigree|Mutations|Phenotype|Nerve Tissue Proteins|Limb Deformities, Congenital 27 KIAA0586 30924151 J. Pathol. 2019 PMC6767539 10.1002/path.5271 0 0 0 86 Humans|Child|Mice|Animals|Hedgehog Proteins|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|Cerebellar Hypoplasia|*Cerebellum|*Eye Abnormalities|*Abnormalities, Multiple|*Retina|Cilia|Ciliopathy|Signal Transduction|Mutations|WNT7A protein, human|Wnt Proteins|Phenotype|Developmental Disabilities|Great Britain|Ireland 27 KLHL7 31856884 Orphanet J Rare Dis 2019 PMC6924004 10.1186/s13023-019-1275-2 0 0 0 90 Humans|*Retinitis Pigmentosa|Electroretinography|Fundus Oculi|Coherence Tomography, Optical|Phenotype|Crisponi syndrome|Facies|Hand Deformities, Congenital|Mutations|Pedigree|Sequencing, Whole Exome|Death, Sudden|Hyperhidrosis|Trismus|KLHL7 protein, human|Autoantigens 30 KLHL7 31497877 Clin. Genet. 2019 10.1111/cge.13639 0 0 0 90 Humans|Child, Preschool|Child|Crisponi syndrome|*Diagnosis, Differential|*Hand Deformities, Congenital|*Facies|*Hyperhidrosis|*Trismus|*Death, Sudden|Phenotype|Bohring syndrome|Intellectual Disability|Homozygote|Abnormalities, Multiple|Pedigree|Receptors, Cytokine|Craniosynostoses|Mutation|Retinitis Pigmentosa|Syndrome 30 KLHL7 30997404 BMJ Open Ophthalmol 2019 PMC6440596 10.1136/bmjophth-2018-000234 1 1 0 90 Humans|Retinitis Pigmentosa|Genes, Dominant|Phenotype|Mutations|Pedigree|Heterozygote|Autoantigens|KLHL7 protein, human 30 KLHL7 30859550 Clin. Genet. 2019 10.1111/cge.13532 1 0 0 90 Humans|Child, Preschool|Child|Crisponi syndrome|*Whole Exome Sequencing|*Exome|*Hand Deformities, Congenital|*Trismus|*Facies|*Hyperhidrosis|*Death, Sudden|Homozygote|Receptors, Cytokine|Mutation|Phenotype|Abnormalities, Multiple|Pedigree|Sweating|Hyperthermia|MAGEL2 protein, human|Proteins 30 LMOD2 31517052 Sci Adv 2019 PMC6726455 10.1126/sciadv.aax2066 1 0 0 42 Humans|Infant, Newborn|*Sarcomeres|*Actin Cytoskeleton|*Heart|Familial dilated cardiomyopathy|Cardiomyopathy, Dilated|Tropomodulin|Muscle Proteins|Myocardium|Tropomyosin|*Mutation|Muscle Contraction|Cytoskeletal Proteins|Heart Failure 19 LMOD3 31572445 Front Genet 2019 PMC6753228 10.3389/fgene.2019.00835 0 0 0 46 Female|Pregnancy|Humans|Myopathies, Nemaline|*Heterozygote|Muscle Proteins|Sarcomeres|Sequencing, Whole Exome|Muscle, Skeletal|Mutation 22 LMOD3 31517052 Sci Adv 2019 PMC6726455 10.1126/sciadv.aax2066 1 0 0 46 Humans|Infant, Newborn|*Sarcomeres|*Actin Cytoskeleton|*Heart|Familial dilated cardiomyopathy|Cardiomyopathy, Dilated|Tropomodulin|Muscle Proteins|Myocardium|Tropomyosin|*Mutation|Muscle Contraction|Cytoskeletal Proteins|Heart Failure 22 LMOD3 31228046 J. Muscle Res. Cell. Motil. 2019 PMC6726674 10.1007/s10974-019-09519-9 5 0 0 46 Adult|Humans|Animals|Child|*Myopathies, Nemaline|Activities of Daily Living|nebulin|Muscle Proteins|Muscle Weakness|Muscle, Skeletal|Actin|Sarcomeres|Phenotypes|Mutations|Hypotonia|Electron Microscopy|KLHL40 protein, human 22 LMOD3 31193276 Biochem Biophys Rep 2019 PMC6525281 10.1016/j.bbrep.2019.100649 0 0 0 46 Mice|Animals|*Hair Cells, Vestibular|*Culture Media, Conditioned|*Hair Cells, Auditory, Inner|*Hair Cells, Auditory|*Embryonic Stem Cells|*Vestibule, Labyrinth|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|*Hematopoiesis|Mice, Transgenic|Vestibular Diseases 22 LMOD3 30642739 Neuromuscul. Disord. 2019 10.1016/j.nmd.2018.12.009 2 0 0 46 Humans|Female|*Myopathies, Nemaline|*Follow-Up Studies|Sarcomeres|Muscle Proteins|*Mutations|Muscle, Skeletal|Actins|Sequencing, Whole Exome|Microfilament Proteins|Homozygote 22 LOXHD1 31547530 Genes (Basel) 2019 PMC6826470 10.3390/genes10100735 2 0 0 9 Humans|*Mutations|Pedigree|Hearing Loss, Sensorineural|Genetic Association Studies|Asian Continental Ancestry Group|High-Throughput Nucleotide Sequencing|Phenotype|Mutation, Missense|Carrier Proteins 34 LOXHD1 30973406 Cornea 2019 PMC6554040 10.1097/ICO.0000000000001952 0 0 0 9 Humans|*Fuchs' Endothelial Dystrophy|*Trinucleotide Repeat Expansion|Transcription Factor 4|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Endothelium, Corneal|Genetic Predisposition to Disease|Single Nucleotide Polymorphisms|Blotting, Southern|Genotype|Transcription Factors|Polymerase Chain Reaction|TCF4 protein, human 34 LOXHD1 30760222 BMC Med. Genet. 2019 PMC6373029 10.1186/s12881-019-0758-2 2 1 0 9 Humans|*Whole Exome Sequencing|*Hearing Loss|Deafness, Autosomal Recessive 77|Hearing Loss, Sensorineural|*Mutation, Missense|*Chinese|Pedigree|Deafness|Heterozygote|Phenotype|Genotype|High-Throughput Nucleotide Sequencing|Carrier Proteins|LOXHD1 protein, human 34 LOXHD1 30622556 Front Genet 2019 PMC6309105 10.3389/fgene.2018.00681 1 0 0 9 Humans|*DNA Copy Number Variations|*Uniparental Disomy|*Alleles|Italy|*Hearing Loss|Hearing Loss, Sensorineural|Connexins|*Genomics|Genetic Predisposition to Disease|Pedigree|Deafness|*Cohort Studies 34 LYPLAL1 31739742 Circ. Res. 2019 10.1161/CIRCRESAHA.119.315246 2 0 0 45 71 LYPLAL1 31682594 PLoS Comput. Biol. 2019 PMC6855562 10.1371/journal.pcbi.1007460 0 0 0 45 Humans|Male|Neoplasm Recurrence, Local|Radiosensitivity|*Prostate Cancer|Network, Gene|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Cell Line, Tumor|MicroRNAs|Down-Regulation|Biomarkers, Tumor|RNA, Messenger|Signal Transduction|Gene Expression Profiles|siRNA|*Relapse|PAK7 protein, human|FOXL1 protein, human|Forkhead Transcription Factors 71 LYPLAL1 31668939 J Ren Nutr 2019 10.1053/j.jrn.2019.09.002 0 0 0 45 *Intra-Abdominal Fat|Nonalcoholic Fatty Liver Disease|Obesity, Abdominal|Body Mass Index|Obesity|Liver|*Chronic Kidney Disease|Albuminuria|Cross-Sectional Studies 71 LYPLAL1 31334442 Hepatol Commun 2019 PMC6601321 10.1002/hep4.1353 2 7 0 45 Humans|*Non-alcoholic Fatty Liver Disease|*Genetic Predisposition to Disease|*Insulin Resistance|*Diabetes Mellitus|Liver|Polymorphism, Single Nucleotide|Lipase|Gene Frequency|B-insulin|*Insulin|Body Mass Index|Obesity|Triglycerides|Membrane Proteins|Genotype|Adaptor Proteins, Signal Transducing|*Biotin 71 LYPLAL1 31025105 Hum. Genet. 2019 10.1007/s00439-019-02023-7 0 0 0 45 Humans|Genotype|*Face|Phenotypes|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Asian|*Transcription Factors|European Continental Ancestry Group|Traits, Complex|Genetics, Population|Genetic Variation|TNFSF12 protein, human|*Cytokine TWEAK|EDAR protein, human|Edar Receptor|PRDM16 protein, human|DNA-Binding Proteins|PAX3 protein, human 71 LYPLAL1 30646922 Lipids Health Dis 2019 PMC6334439 10.1186/s12944-018-0877-3 0 1 0 45 Humans|*Non-alcoholic Fatty Liver Disease|*Case-Control Studies|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Gene Frequency|Alleles|Asian Continental Ancestry Group|Lipase|Liver|Membrane Proteins|Adaptor Proteins, Signal Transducing|Ethnic Groups|TM6SF2 protein, human 71 LYPLAL1 30639359 Cell Metab. 2019 PMC6447452 10.1016/j.cmet.2018.12.013 6 0 0 45 Humans|Female|Mice|Male|Animals|*Mice, Inbred C57BL|*Mice, Inbred DBA|Obesity|Adipose Tissue|Insulin Resistance|*Mitochondria|Adiposity|Diet, High-Fat|Sex Differences|*Phenotypes 71 LZTR1 31883238 Mol Genet Genomic Med 2019 PMC7057116 10.1002/mgg3.1107 1 0 0 108 Humans|Animals|*Noonan Syndrome|*Zebrafish|ras Proteins|Mutation|*Cardiac Hypertrophy|Transcription Factors|*Vascular Malformations|LZTR1 protein, human 80 LZTR1 31825158 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61445 0 1 0 108 Humans|*Noonan Syndrome|Phenotypes|Genotype|Mutation|K-ras Genes|Transcription Factors|Signal Transduction|Cohort Studies|LZTR1 protein, human 80 LZTR1 31666243 Arch. Dis. Child. 2019 10.1136/archdischild-2018-316634 0 0 0 108 Child|Humans|*Prevalence|*Heart Defects, Congenital|22q11.2 Deletion Syndrome|Shprintzen Golberg craniosynostosis|Arachnodactyly|Marfan Syndrome|Chromosome Deletion|DNA Copy Number Variations|Craniosynostoses 80 LZTR1 31533111 Horm Res Paediatr 2019 10.1159/000502741 0 0 0 108 Humans|*Noonan Syndrome|*Genotype|Phenotype|ras Proteins|Mutations|Pedigree|Transcription Factors|LZTR1 protein, human 80 LZTR1 31439678 Haematologica 2019 PMC7109753 10.3324/haematol.2019.230375 1 0 0 108 *Histiocytic Sarcoma|*Sarcoma|*Genetic Profile|Mutation|*Soft Tissue Neoplasms|Genomics 80 LZTR1 31438995 Orphanet J Rare Dis 2019 PMC6704629 10.1186/s13023-019-1176-4 0 0 0 108 Humans|Schwannomatosis|*Neurofibromatoses|*Neurilemmoma|*Skin Neoplasms|Neurofibromatosis 2|SMARCB1 Protein|Germ-Line Mutation|Transcription Factors|Pedigree 80 LZTR1 31425178 Curr Opin Oncol 2019 10.1097/CCO.0000000000000579 0 0 0 108 *Neurofibromatosis 2|Schwannomatosis|Neurofibromatoses|Schwannoma|SMARCB1 protein, human|SMARCB1 Protein|Neuroma, Acoustic|Skin Neoplasms|Treatment Outcome|Phenotype|Genotype 80 LZTR1 31424590 Brain Pathol. 2019 10.1111/bpa.12780 1 0 0 108 Humans|Schwannomatosis|*Diagnosis, Differential|*Neurofibromatoses|*Neurilemmoma|*Skin Neoplasms|Neurofibromatosis Type II|SMARCB1 protein, human|SMARCB1 Protein|Genes, Neurofibromatosis 2|Neurofibromin 2|Transcription Factors|Mutations, Germline|*Epidermis|Mutation|Genetic Predisposition|Nerve Fibers 80 MPZ 31882567 Diabetes 2019 10.2337/db19-0517 0 0 0 2030 Humans|Mice|Animals|*Liver X Receptors|Diabetes Mellitus, Type 2|*Diabetes Mellitus, Experimental|NOX4 protein, human|*NADPH Oxidase 4|*Schwann Cells|superoxide-forming enzyme|NADPH Oxidases|Diabetic Neuropathies|Reactive Oxygen Species|Signal Transduction 465 MPZ 31827005 Neurology 2019 PMC7011687 10.1212/WNL.0000000000008672 0 0 0 2030 *Charcot-Marie-Tooth Disease|Myelin P0 Protein|*Sequencing, Next-Generation|Genetic Testing|Connexins|Gene Duplication|Genotype|Gene Deletion|Demyelinating Diseases 465 MPZ 31809032 Inorg Chem 2019 10.1021/acs.inorgchem.9b02799 0 0 0 2030 *Iridium|Molecular Structure|Organometallic Compounds|Quantum Theory|Ligands|Models, Molecular|Crystallography, X-Ray 465 MPZ 31777123 Neuropathology 2019 10.1111/neup.12604 0 0 0 2030 Male|Humans|Animals|Child|Charcot-Marie-Tooth disease, Type 4E|*Charcot-Marie-Tooth Disease|Myelin P0 Protein|*Homozygote|*Mutation|Myelin Proteins|Sural Nerve|Point Mutation|Phenotype|Neural Conduction|Heterozygote|Genotype|Myelin|CNTNAP1 protein, human|Cell Adhesion Molecules, Neuronal|PMP22 protein, human 465 MPZ 31769568 Cell Biol. Int. 2019 10.1002/cbin.11268 0 0 0 2030 *Myelin P0 Protein|Charcot Marie Tooth Disease|*Mutation|Hereditary Sensory and Motor Neuropathy|Point Mutation|Demyelinating Diseases|Molecular Dynamics Simulation|*Cell Membrane 465 MPZ 31760634 Adv. Exp. Med. Biol. 2019 10.1007/978-981-32-9636-7_1 1 0 0 2030 *Remyelination|*Schwann Cells|Oligodendrocytes|Myelin Sheath|Cells, Glial|Peripheral Nervous System|Neurogenesis|Cell Differentiation|ADP-ribosylation factor 6|ADP-Ribosylation Factors|Signal Transduction|*Regulatory B-Cells 465 MYO3A 31484049 Structure 2019 10.1016/j.str.2019.08.007 0 1 0 81 *Protein Binding|Protein Structure, Secondary|Protein Folding|Amino Acid Sequence|Models, Molecular 50 MYO3A 31279628 Structure 2019 10.1016/j.str.2019.06.004 1 1 0 81 Animals|Chlorocebus aethiops|*Protein Binding|Myosin Type III|Pseudopodia|Myosin Heavy Chains|Actins|COS Cells|Ankyrin|Tandem Repeats 50 MYO3A 31083078 Otol. Neurotol. 2019 10.1097/MAO.0000000000002234 0 0 0 81 Humans|*African Americans|*Hearing Loss|*Deafness|Connexin 26|Connexins|Gene Frequency|Genotype|Mutation 50 MYO3A 30682115 PLoS ONE 2019 PMC6347456 10.1371/journal.pone.0211261 2 1 0 81 Humans|*Cochlear Implantation|Taiwan|*Hearing Loss|*Massively Parallel Sequencing|Hearing Loss, Sensorineural|*Mutation|Deafness|Pedigree|Connexins|Sequence Analysis, DNA|Asian Continental Ancestry Group 50 MYPN 31647200 J Cachexia Sarcopenia Muscle 2019 PMC7015241 10.1002/jcsm.12486 2 2 0 235 Humans|*Serum Response Factor|Nemaline Myopathy|Muscle Proteins|Cap Myopathy|Myopathies, Structural, Congenital|Myopathy, Congenital|Muscle, Skeletal|Homozygote|Cell Nucleus|Sarcomere|Trans-Activators|Actins|Mutation|Heterozygote|Pedigree|Cardiomyopathy, Restrictive 32 MYPN 31524317 Ann Noninvasive Electrocardiol 2019 10.1111/anec.12687 0 0 0 235 Female|Humans|Middle Aged|*Cardiomyopathy, Dilated|*Mutation, Missense|myosin-binding protein C|*Atrioventricular Block|Carrier Proteins|Mutations|Pedigree|Muscle Proteins|Cardiomyopathies|Genetic Testing|Phenotype|*Coronary Artery Disease|Arrhythmias, Cardiac|*Cytoskeletal Proteins 32 MYPN 31133047 Skelet Muscle 2019 PMC6535860 10.1186/s13395-019-0199-9 2 0 0 235 Humans|*Hallux|*Myopathy, Congenital|*Homozygote|nebulin|Muscle Proteins|Cap Myopathy|Myopathies, Structural, Congenital|*Mutation|Muscle, Skeletal|Pedigree|alpha Actinin|Cardiomyopathy, Restrictive|Cardiac Muscle|MYPN protein, human 32 MYPN 30953456 BMC Med. Genet. 2019 PMC6451262 10.1186/s12881-019-0793-z 0 0 0 235 *Cardiomyopathy, Restrictive|*Troponin I|Troponin T|Cardiomyopathy, Hypertrophic|Pedigree|Mutation 32 MYPN 30764827 BMC Med Genomics 2019 PMC6375196 10.1186/s12920-019-0478-7 0 0 0 235 Humans|*Exome|Lebanon|*Whole Exome Sequencing|*Cardiomyopathies|Sudden Cardiac Death|Mutation|Mutation, Missense 32 OPA3 31881642 Cancers (Basel) 2019 PMC7016999 10.3390/cancers12010065 1 0 0 152 Humans|*Pancreatic Cancer|*Mitochondria|*Pancreas|Genes, ras|ras Proteins|Mutations|*Energy Metabolism|Gene Expression Regulation, Neoplastic 76 OPA3 31564785 Physiol Mol Biol Plants 2019 PMC6745579 10.1007/s12298-019-00698-w 0 0 0 152 *Dioscorea|Plant Tubers|Starch 76 OPA3 31119193 Neurol Genet 2019 PMC6501639 10.1212/NXG.0000000000000322 0 0 0 152 Humans|*Optic Atrophy, Autosomal Dominant|*Phenotype|*Cataract|Optic Atrophy|Pedigree|*Optic Atrophies, Hereditary|Mutation|Proteins 76 OPA3 31111050 Biomed Res Int 2019 PMC6487127 10.1155/2019/3698742 0 2 0 152 76 OPA3 30991875 J. Int. Med. Res. 2019 PMC6567723 10.1177/0300060519838385 0 0 0 152 *Papilloma, Inverted|*Squamous Cell Carcinoma|Paranasal Sinus Neoplasms|*Cell Transformation, Neoplastic|Nose Neoplasms|Biomarkers, Tumor|*Respiratory Tract Neoplasms 76 PASD1 31558691 Med. Sci. Monit. 2019 PMC6761850 10.12659/MSM.916308 0 3 0 15 Humans|Male|*Glioma|*Cell Proliferation|Brain Neoplasms|Apoptosis|Tumorigenesis|Downregulation|Cell Line, Tumor|Antigens, Neoplasm|Immunohistochemistry|*Cell Death|PASD1 protein, human|Antigens, Nuclear 19 PASD1 31478431 Immunotherapy 2019 10.2217/imt-2019-0073 0 0 0 15 Male|HLA-A*24:02 antigen|HLA-A24 Antigen|*Colorectal Cancer|T-Lymphocytes, Cytotoxic|HLA-A2 Antigen|Antigens, Neoplasm|*Peptides|CD8-Positive T-Lymphocytes|Immunotherapy|Epitopes|ELISPOT|Antigens, Nuclear|Cell Line, Tumor|*Colonic Neoplasms|Asia|Malaysia 19 PCDH12 30771304 Dev. Biol. 2019 PMC6451886 10.1016/j.ydbio.2019.01.019 0 0 0 30 Humans|Animals|Mice|Female|Pregnancy|*Trophoblasts|*DNA Methylation|*Glycogen|*Placenta|Placental Development|Intrauterine Growth Restriction|Genomic Imprinting|Gene Expression Regulation, Developmental|Embryo, Mammalian|Transcriptome Profile|Cell Proliferation|MicroRNAs|MIRN126 microRNA, human 27 PCDH15 31704577 Int. J. Pediatr. Otorhinolaryngol. 2019 10.1016/j.ijporl.2019.109756 1 0 0 138 *High-Throughput Nucleotide Sequencing|Iran|*Hearing Loss, Sensorineural|*Deafness|Connexins|Mutations|Pedigree 204 PCDH15 31696427 Environ Sci Pollut Res Int 2019 10.1007/s11356-019-06470-7 1 0 0 138 Humans|*Hearing Loss, Noise-Induced|Noise, Occupational|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|Asian Continental Ancestry Group|Genotype|DNA-Binding Proteins|Transcription Factors|Case-Control Studies|Logistic Models|POU4F3 protein, human|Homeodomain Proteins|Transcription Factor Brn-3C|GRHL2 protein, human 204 PCDH15 31540999 eNeuro 2019 PMC6800292 10.1523/ENEURO.0403-18.2019 4 8 0 138 Cell Adhesion Molecules, Neuronal|Bipolar Disorder|Schizophrenia|Serine Endopeptidases|Extracellular Matrix Proteins|Nerve Tissue Proteins 204 PCDH15 31399498 Biochem. J. 2019 PMC6717114 10.1042/BCJ20190453 1 1 0 138 Hair Cells, Auditory|Ear, Inner|*Mutations|Mechanotransduction, Cellular|Hearing|Protein Binding|Cadherins|Deafness|Protein Precursors|Models, Molecular 204 PCDH15 31231422 Front Genet 2019 PMC6558366 10.3389/fgene.2019.00501 1 0 0 138 *Usher Syndromes|Cuba|*Genetic Screening|Pedigree|Mutation|High-Throughput Nucleotide Sequencing|Adaptor Proteins, Signal Transducing|Europe|Africa|South America 204 PCDH15 31072932 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6561218 10.1073/pnas.1902163116 6 0 0 138 Animals|Hair Cells, Auditory|*Hearing|Cadherins|Ear, Inner|Mechanotransduction, Cellular|*Hearing Tests|Protein Precursors|*Elasticity 204 PCDH15 30947719 Environ Health 2019 PMC6449917 10.1186/s12940-019-0471-9 1 0 0 138 Humans|*Hearing Loss, Noise-Induced|*Genetic Predisposition to Disease|*Polymorphism, Single Nucleotide|Noise, Occupational|Chinese|Genotype|Case-Control Studies|Occupational Exposure|Logistic Models 204 PCDH15 30617060 Cold Spring Harb Perspect Med 2019 10.1101/cshperspect.a033142 3 0 0 138 Humans|Mice|Animals|Hair Cells, Auditory|Stereocilia|Cilia|Mechanotransduction, Cellular|Cadherins|Protein Precursors|Protein Tyrosine Phosphatase|Usher syndrome, type 2A|Usher Syndromes|STRC protein, human|Membrane Proteins|Pcdh15 protein, mouse|Cdh23 protein, mouse|Ush2a protein, mouse|Extracellular Matrix Proteins 204 PDE6H 31696970 Anim. Genet. 2019 PMC7004202 10.1111/age.12873 2 0 0 11 Animals|Rabbits|Bayes Theorem|*Genome|Breeding|*Genomics|Phenotype|Meat|Genotype|SNPs 27 PDE6H 31237654 Invest. Ophthalmol. Vis. Sci. 2019 PMC6594318 10.1167/iovs.19-27047 2 0 0 11 Achromatopsia 1|*Color Vision Defects|*Retina|Electroretinography|Retinal Cone Photoreceptor Cells|Cyclic Nucleotide-Gated Cation Channels|Ophthalmoscopy|Visual Acuity|Tomography, Optical Coherence|Mutations|Phenotype 27 pdlim3 31424159 J. Cell. Mol. Med. 2019 PMC6787498 10.1111/jcmm.14607 3 0 0 60 Humans|Mice|Animals|*Cardiomyopathy, Dilated|*Sarcomeres|Case-Control Studies|*Polymorphism, Genetic|PDLIM4 protein, human|LIM Domain Proteins|PDLIM3 protein, human|Exons|Genetic Predisposition to Disease|Genotype|Asian Continental Ancestry Group|Mutations|Allele|Microfilament Proteins|Myocardial Contraction|Systole|DNA-Binding Proteins|PDLIM5 protein, human 35 pdlim3 31011911 Pathol. Oncol. Res. 2019 10.1007/s12253-019-00657-6 2 0 0 60 Humans|*Urinary Bladder Neoplasms|*Prognosis|*Urinary Bladder|Neoplasm Recurrence, Local|Networks, Gene|*Carcinoma, Transitional Cell|Gene Expression Profiling|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Genetic Markers|Gene Expression|Disease Progression|Phenotype|MSRB3 protein, human|Methionine Sulfoxide Reductases|PDLIM3 protein, human|Microfilament Proteins|LIM Domain Proteins 35 PEPD 31739742 Circ. Res. 2019 10.1161/CIRCRESAHA.119.315246 2 0 0 553 172 PEPD 31595454 J. Ind. Microbiol. Biotechnol. 2019 10.1007/s10295-019-02240-z 1 5 0 553 *Streptomyces|*Polylysine|Streptomyces albulus|*Transcriptome|Fermentation|Glycerol|Food Preservatives|*Poly A|*Computational Biology|Hydrogen-Ion Concentration 172 PEPD 31181254 Protein Expr. Purif. 2019 10.1016/j.pep.2019.06.002 0 1 0 553 *Aspergillus niger|*Pichia|Cloning, Molecular|Fungal Proteins|Enzyme Stability|Gene Expression|*Saccharomycetales|*Endopeptidases|Hydrogen-Ion Concentration|Kinetics|*Antigens, Fungal|Temperature 172 PEPD 31145772 Acta Biochim. Pol. 2019 10.18388/abp.2018_2632 0 2 0 553 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Case-Control Studies|*Asian|SNPs|Genetic Predisposition to Disease|Genetic Loci|Genotype|Odds Ratio|Alleles|Obesity|Phenotype|WWOX protein, human|WW Domain-Containing Oxidoreductase|Tumor Suppressor Proteins 172 PEPD 30953690 Res. Microbiol. 2019 10.1016/j.resmic.2019.03.004 0 4 0 553 *Listeria monocytogenes|*ELISA|Listeria|Antibody Specificity|Food Microbiology|Culture Media|Antigens, Bacterial|Blotting, Western|Epitopes|Antibodies, Monoclonal|Serotyping|Bacterial Proteins|Species Specificity 172 PEPD 30734899 Mol. Biol. Rep. 2019 10.1007/s11033-019-04654-5 2 1 0 553 Humans|*Osteoarthritis, Knee|*Epistasis, Genetic|SNPs|Genotype|Gene Frequency|Genetic Predisposition to Disease|Alleles|Asian Continental Ancestry Group|Case-Control Studies|Articular Cartilage|Risk Factors|Mexico|PON1 protein, human|Aryldialkylphosphatase|ADIPOQ protein, human|Adiponectin 172 PEPD 30674653 Sci Transl Med 2019 PMC6409101 10.1126/scitranslmed.aav1620 4 0 0 553 Humans|ERBB2 protein, human|*Receptor, ErbB-2|Trastuzumab|Drug Resistance, Neoplasm|Cell Line, Tumor|Antibodies, Monoclonal, Humanized|Xenograft Model Antitumor Assays|Signal Transduction 172 PEPD 30656471 Eur Spine J 2019 10.1007/s00586-018-05866-2 2 0 0 553 *Ligamentum Flavum|*Osteogenesis|*Spinal Cord Diseases|Decompression, Surgical|*Endoscopy|Ossification, Heterotopic|Thoracic Vertebrae|Treatment Outcome|Far East 172 PITX3 31825844 Cell Rep 2019 10.1016/j.celrep.2019.11.027 1 1 0 344 *Circadian Clocks|Suprachiasmatic Nucleus|*Energy Expenditure|Period Circadian Proteins|Circadian Rhythm|Light-Dark Cycles|Hypothalamus|Adipose Tissue, Brown|Motor Activity|Liver|Light 453 PITX3 31749842 Front Genet 2019 PMC6844290 10.3389/fgene.2019.01099 0 1 0 344 Animals|Rats|SLC6A3 protein, human|*Dopamine Plasma Membrane Transport Proteins|*Epigenesis, Genetic|Autism Spectrum Disorder|Dopamine|Attention Deficit-Hyperactivity Disorder|Mesencephalon|mRNA 453 PITX3 31644786 J. Gerontol. A Biol. Sci. Med. Sci. 2019 10.1093/gerona/glz256 0 1 0 344 Humans|Mice|Animals|GDNF protein, human|*Glial Cell Line-Derived Neurotrophic Factor|BDNF protein, human|*Brain-Derived Neurotrophic Factor|*Parkinson Disease|*Electroacupuncture|Substantia Nigra|Dopaminergic Neurons|Corpus Striatum|*Disease Models, Animal|6 Hydroxydopamine|1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|Dopamine|Nerve Degeneration|Mice, Inbred C57BL|Neostriatum|Neuroprotective Agents 453 PITX3 31641054 J. Neurosci. 2019 PMC6880462 10.1523/JNEUROSCI.1160-19.2019 0 0 0 344 Humans|*Mesencephalon|*Pluripotent Stem Cell|*Neural Stem Cell|*Parkinsonian Disorders|Dopaminergic Neurons|LIM-Homeodomain Proteins|Embryonic Stem Cells|Cell Differentiation|Homeodomain Proteins|Transcription Factors|Parkinson Disease|Stem Cell Transplantation|Dopamine|Cells, Cultured|LMX1A protein, human 453 PITX3 31547185 Medicina (Kaunas) 2019 PMC6843810 10.3390/medicina55100616 0 0 0 344 453 PITX3 31479653 Exp. Eye Res. 2019 PMC6867612 10.1016/j.exer.2019.107787 1 0 0 344 Humans|Mice|Cats|Animals|*Lens, Crystalline|Cataract|*Cell Line|Eye Proteins|Epithelial Cells|Genes, Homeobox|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Gene Expression|*Epithelium|RNA, Messenger|Cells, Cultured|Membrane Proteins|INPPL1 protein, human|Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|Inppl1 protein, mouse 453 PITX3 31352199 Stem Cell Res 2019 10.1016/j.scr.2019.101499 0 0 0 344 Humans|*Human Embryonic Stem Cells|*Embryonic Stem Cells|homeobox protein PITX3|Homeodomain Proteins|Transcription Factor|*Cell Line|Cell Differentiation|Mesencephalon|Germ Layers|Neurons|Gene Expression Regulation, Developmental|Dopamine 453 PITX3 31317490 Mol. Neurobiol. 2019 10.1007/s12035-019-01701-x 1 0 0 344 Animals|Rats|*Transcription Factors|*GABAergic Neurons|*Dopamine|Cell Differentiation|Tyrosine Hydroxylase|*Neurotransmitter|Nuclear Receptor Subfamily 4, Group A, Member 2|DNA-Binding Proteins|Mesencephalon|Dopaminergic Neurons|Stem Cells|*Phenotype|*Hematopoiesis|Cell Transdifferentiation|Ascl1 protein, rat|Basic Helix-Loop-Helix Transcription Factors 453 PITX3 31310388 J. Cell. Biochem. 2019 10.1002/jcb.29109 0 0 0 344 Humans|Rats|Animals|*Dopamine|*Glial Cell Line-Derived Neurotrophic Factor|Dopaminergic Neuron|Oxidopamine|Mesencephalon|Cell Differentiation|Corpus Striatum|Homeodomain Proteins|Parkinson Disease|Tyrosine Hydroxylase|*Multipotent Stem Cells|Transcription Factors|*Signal Transduction|Cells, Cultured|Brain-Derived Neurotrophic Factor|Medium, Conditioned 453 PITX3 31277075 Neuropsychopharmacology 2019 PMC6901441 10.1038/s41386-019-0457-x 4 2 0 344 Male|Female|*Cocaine|*Dopaminergic Neurons|*GTPase|*Corpus Striatum|SLC6A3 protein, human|Dopamine Transporter|Receptors, Dopamine D2|Receptors, Dopamine D1|Dopamine|*Gene Silencing 453 PITX3 31248447 Stem Cell Res Ther 2019 PMC6598262 10.1186/s13287-019-1294-x 0 0 0 344 Humans|*Dopaminergic Neurons|Cell Differentiation|Stem Cells|Parkinson Disease|*Adult Germline Stem Cells|Neurogenesis|*Phenotypes|Dopamine|Cell Therapy|Stem Cell Transplantation|Cells, Cultured 453 POU5F1B 31552188 Front Oncol 2019 PMC6746928 10.3389/fonc.2019.00874 4 0 0 44 Humans|*Neoplastic Cells, Circulating|Pilot Projects|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Prognosis|Liquid Biopsy|Biomarkers, Tumor|Kaplan-Meier Estimate|Gene Expression Regulation, Neoplastic|*Cell Count|Cell Line, Tumor 19 POU5F1B 31271156 Med. Sci. Monit. 2019 PMC6625577 10.12659/MSM.914352 2 0 0 44 Humans|*Pseudogenes|*Prognosis|*Leukemia, Myeloid, Acute|Receiver Operating Characteristic|Kaplan-Meier Analysis|Area Under Curve|Biomarkers, Tumor|Real-Time PCR, Quantitative|Remission Induction|Cohort Studies|*Transcription Factors 19 POU5F1B 30763293 Med. Sci. Monit. 2019 PMC6383439 10.12659/MSM.913066 0 0 0 44 Humans|*RNA, Long Noncoding|*Esophageal Cancer|*Radiosensitivity|Esophageal Squamous Cell Carcinoma|Cell Proliferation|Apoptosis|Upregulation|Cell Line, Tumor|Gene Knockdown Techniques|Gene Expression Regulation, Neoplastic|RNA, Small Interfering 19 POU5F1B 30762028 Med. Sci. Monit. 2019 PMC6383437 10.12659/MSM.912109 4 1 0 44 Humans|Female|*Down-Regulation|*Uterine Cervical Neoplasms|*Pseudogenes|*Transcription Factor 4|*Transcription Factor POU|*Cell Proliferation|*Upregulation|*Apoptosis|POU5F1 protein, human|*Octamer Transcription Factor-3|*Transcriptional Activation|HeLa Cells|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|CEBPB protein, human|*CCAAT-Enhancer-Binding Protein-beta|MicroRNAs 19 PRCD 31884666 Adv. Exp. Med. Biol. 2019 10.1007/978-3-030-27378-1_87 0 0 0 11 Humans|Dogs|Animals|*Rhodopsin|*Binding Protein|Retinitis Pigmentosa|Retinal Cone Photoreceptor Cells|Retinal Rod Photoreceptor Cells|Cone-Rod Degeneration|Eye Proteins|Retina|Membrane Proteins|Point Mutation|Mutation|Protein Transport 66 PRCD 31640229 Animals (Basel) 2019 PMC6826964 10.3390/ani9100844 0 0 0 11 Dogs|Animals|*Allele Frequency|Cone-Rod Degeneration|*Mutation|Retinal Degeneration|Pedigree|Dog Diseases|Polymerase Chain Reaction 66 PRCD 31628458 Hum. Mol. Genet. 2019 10.1093/hmg/ddz248 2 0 0 11 Humans|Mice|Animals|Dogs|Photoreceptors, Cone|Retinal Degeneration|Cone-Rod Degeneration|Retinitis Pigmentosa|Retina|Eye Proteins|Retinal Pigment Epithelium|Mice, Knockout|Membrane Proteins|Electroretinography|Mutations|*Cilia|Morphogenesis|PRCD protein, mouse 66 PRCD 31189593 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6601265 10.1073/pnas.1906421116 5 0 0 11 Mice|Humans|Animals|Dogs|*Cone-Rod Degeneration|*Photoreceptor Cells|*Cone Dystrophy|Retinitis Pigmentosa|Eye Proteins|Retinal Degeneration|Membrane Proteins|Retinal Pigment Epithelium|*Signal Transduction|Mice, Knockout|Mutations|PRCD protein, mouse 66 PRDM12 31584034 J Indian Soc Pedod Prev Dent 2019 10.4103/JISPPD.JISPPD_340_18 0 0 0 32 Child|Male|Infant|Humans|Indifference to Pain, Congenital, Autosomal Recessive|*Pain Insensitivity, Congenital|*Channelopathies|Hypohidrosis|Self Mutilation|Pain|Mental Retardation|Nerve Tissue Proteins|Carrier Proteins|Mutation|Prdm12 protein, human 32 PRDM12 30917309 Cell Rep 2019 10.1016/j.celrep.2019.02.097 5 2 0 32 Humans|Mice|Animals|*trkA Receptor|*Receptor, Nerve Growth Factor|*Nociceptive Neuron|NGFR protein, human|*Receptors, Nerve Growth Factor|NEUROG1 protein, human|*Nerve Tissue Proteins|Indifference to Pain, Congenital, Autosomal Recessive|Congenital Insensitivity To Pain|Basic Helix-Loop-Helix Transcription Factors|Neurogenesis|Carrier Proteins|Neurons|Cell Lineage|Signal Transduction|Channelopathies|Prdm12 protein, human 32 PRDM12 30917305 Cell Rep 2019 10.1016/j.celrep.2019.02.098 5 0 0 32 Humans|Mice|Animals|*Nociceptors|*Neurogenesis|NeuroD protein|Nerve Tissue Proteins|Basic Helix-Loop-Helix Transcription Factors|Neurons|Transcription Factors|Carrier Proteins|Cell Lineage|Pain Perception|Gene Expression Regulation|Prdm12 protein, human 32 PRDM12 30813944 Neural Dev 2019 PMC6391800 10.1186/s13064-019-0129-x 1 28 0 32 Animals|*Zebrafish|*Neural Tube|Transcription Factors|Zebrafish Proteins|Homeodomain Proteins|Interneurons|Gene Expression Regulation, Developmental|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Motor Neurons|Spinal Cord|Nkx6.1 protein, zebrafish 32 PRDM12 30616239 Med. Sci. Monit. 2019 PMC6330996 10.12659/MSM.912294 3 1 0 32 Humans|Male|Set2 protein, human|Methyltransferase, Histone|Histone|*Prostate Cancer|Protein Methyltransferases|Polycomb Repressive Complex 2|DNA-Binding Proteins|Nuclear Proteins|Enhancer of Zeste Homolog 2 Protein|Lysine|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Carrier Proteins|SETD6 protein, human|Prdm12 protein, human|Nerve Tissue Proteins 32 PSAP 31864418 Acta Neuropathol Commun 2019 PMC6925443 10.1186/s40478-019-0862-8 0 0 0 532 Animals|Mice|Humans|*Progranulins|*Alzheimer Disease|lysosomal proteins|*Neuropathology|Amyloid beta-Peptides|Frontotemporal Lobar Degeneration|Plaque, Amyloid|Frontotemporal Dementia|Intercellular Signaling Peptides and Proteins|*Brain|Microglia|Mice, Knockout|Lysosomes|Granulins|Neurons|Disease Models, Animal|sortilin|Adaptor Proteins, Vesicular Transport 728 PSAP 31842534 J Audiol Otol 2019 PMC7141988 10.7874/jao.2019.00367 0 0 0 532 Adult|Humans|*Hearing Aids|*Speech Intelligibility|Hearing Loss, Sensorineural|Speech Perception|Auditory Threshold|Audiometry, Pure-Tone|*Sound|*Hearing Loss 728 PSAP 31798302 Subst Abuse 2019 PMC6868565 10.1177/1178221819884328 0 0 0 532 Humans|Male|*Aggression|*Alcohol Drinking|Ethanol|Students|Universities|Questionnaire|Self Report 728 PSAP 31779716 Prehosp Disaster Med 2019 10.1017/S1049023X19005077 0 0 0 532 Humans|United States|*Out-of-Hospital Cardiac Arrest|*Retrospective Studies|Cardiopulmonary Resuscitation|Emergency Medical Services|Electric Countershock|Registries|Patient Discharge 728 PSAP 31761539 Theriogenology 2019 10.1016/j.theriogenology.2019.11.006 0 0 0 532 Female|Cattle|Animals|*Vitrification|*mRNA|*Transcriptome|*Temperature|*Cryoprotective Agents|Oocytes|*Oogenesis|Cryopreservation|Cumulus Cells|Blastocyst|Fertilization in Vitro|Embryonic Development|Helium|Nitrogen|*Cell Growth Processes 728 PSAP 31753030 Virol. J. 2019 PMC6868781 10.1186/s12985-019-1247-0 0 0 0 532 Animals|*Hepatitis E virus|Chickens|Pakistan|Hepatitis E|Avian hepatitis E virus|Poultry Diseases|Base Sequence|Splenomegaly|Phylogeny|Genotypes|Feces 728 PSAP 31727545 Transfus. Apher. Sci. 2019 10.1016/j.transci.2019.10.004 0 1 0 532 Humans|*Hemeoxygenase 1|*THP-1 Cell Line|*Hemin|Oxygenase, Haem|*Monocytes|Cell Death|Macrophages|*Cytoplasm|Iron|Bilirubin|*Iron, Dietary 728 PSAP 31698007 Hum. Pathol. 2019 10.1016/j.humpath.2019.10.010 0 0 0 532 Humans|Male|Middle Aged|*Prostate|*Prostate Cancer|Androgen Antagonists|*Carcinoma, Acinar Cell|Biomarkers, Tumor|Urinary Bladder Neoplasms|Urothelium|KRT20 protein, human|Cytokeratin 20|Bone Neoplasms|Carcinoma, Transitional Cell|Biopsy|Lymph Nodes 728 PSAP 31682730 Hum. Reprod. 2019 10.1093/humrep/dez204 2 0 0 532 Humans|Male|*Infertility, Male|Azoospermia|Sperm Retrieval|Spermatozoa|Testis|*Mutations|STAG3 protein, human|Nuclear Proteins 728 Purine salvage 31862890 Nat Commun 2019 PMC6925228 10.1038/s41467-019-13694-1 2 0 0 0 Humans|Male|Aged|*NAD|*Mitochondria|Sarcopenia|*Oxidation-Reduction|Muscle, Skeletal|Oxidative Phosphorylation|Aging|Muscular Atrophy|Bioenergetic|Signal Transduction|Oxidative Stress|Jamaica|Singapore 2750 RNASEH2A 31559893 J. Child Neurol. 2019 10.1177/0883073819870944 0 0 0 81 Autoimmune Diseases of the Nervous System|Nervous System Malformations|*Aicardi Syndrome|Ribonuclease H|Interferon-Induced Helicase, IFIH1|Exodeoxyribonucleases|Phosphoproteins|Mutation 41 RNASEH2A 31130681 J Clin Med 2019 PMC6572054 10.3390/jcm8050750 0 0 0 81 *Interferon|Italy|Nervous System Malformations|Autoimmune Diseases of the Nervous System|*Aicardi Syndrome|Ribonuclease H|SAM Domain and HD Domain-Containing Protein 1|Exodeoxyribonucleases|Adenosine Deaminase|*Antiviral Agents|Phenotype|Monomeric GTP-Binding Proteins|Phosphoproteins|Mutation 41 RNASEH2A 30952201 Pediatr. Dev. Pathol. 2019 10.1177/1093526619837797 0 2 0 81 Nervous System Malformations|Autoimmune Diseases of the Nervous System|*Nervous System Diseases|Interferon-Induced Helicase, IFIH1|*Neuropathology|Mutations|Brain Diseases|Atrophy 41 RNASEH2A 30707351 Hum. Genet. 2019 PMC6373277 10.1007/s00439-018-01966-7 0 0 0 81 Humans|Child|*Lupus Erythematosus, Systemic|Homozygote|Genetic Predisposition to Disease|Alleles|*Sequencing, Whole Genome|Polymorphism, Single Nucleotide|Heterozygote|Mutation|*Risk Factors 41 RNASEH2A 30696738 mBio 2019 PMC6355981 10.1128/mBio.02687-18 0 8 0 81 Humans|Female|*Human Papilloma Virus|*Papillomavirus Infections|HPV 16|Papillomavirus E7 Proteins|Oncogene Proteins, Viral|Human papillomavirus 18|Cervical Cancer|NOVA1 protein, human|*RNA-Binding Proteins|Repressor Proteins|DNA-Binding Proteins|Transcriptome Analyses|RNA, Messenger|Carcinogenesis|Cell Line, Tumor|Keratinocytes|DNA Replication|KHSRP protein, human 41 RNASEH2A 30692772 Ann Indian Acad Neurol 2019 PMC6327704 10.4103/aian.AIAN_12_18 1 2 0 81 Autoimmune Diseases of the Nervous System|Nervous System Malformations|*Aicardi Syndrome|Ribonuclease H|Adenosine Deaminase|Exodeoxyribonucleases|Mutations|Phenotype|*Brain Diseases|Phosphoproteins|Spinal Cord 41 s100a5 31818115 Ceska Gynekol 2019 1 2 0 15 Female|*Tumor Markers|*Serum|S100 Protein Family|TFF3 protein, human|Trefoil Factor-3|*Tumor 39 s100a5 31344532 Environ. Res. 2019 10.1016/j.envres.2019.108538 0 7 0 15 Humans|*Particulate Matter|Air Pollutants|Air Pollution|Particle Size|Epithelial Cells|Bronchi|Pulmonary Disease, Chronic Obstructive|Cell Line 39 SBDS 31882330 J Microbiol Immunol Infect 2019 10.1016/j.jmii.2019.11.003 0 0 0 182 Animals|Proteins|Protein Binding|Bone Marrow Diseases|*Phagocytosis|RNA, Ribosomal|*Acanthamoeba|Cytoskeleton 350 SERPINA9 31171907 Int J Med Sci 2019 PMC6535654 10.7150/ijms.27610 0 1 0 6 19 SGCE 31868164 Elife 2019 PMC6959989 10.7554/eLife.52101 0 0 0 160 Animals|Myoclonic dystonia|Dystonic Disorders|Sarcoglycans|*Cerebellum|Disease Models, Animal|Mutations 208 SGCE 31731261 Parkinsonism Relat. Disord. 2019 10.1016/j.parkreldis.2019.11.004 1 0 0 160 Humans|*Dystonic Disorders|*Dystonia|*Phenotypes|*Sequencing, Whole Genome|Genetic Testing|Pedigree|Mutation|Nuclear Proteins|DNA-Binding Proteins|Apoptosis Regulatory Proteins 208 SGCE 31706131 Parkinsonism Relat. Disord. 2019 10.1016/j.parkreldis.2019.10.015 0 0 0 160 Humans|Myoclonic dystonia|*Syndrome|*Dystonic Disorders|*Dystonia|*Phenotype|Sarcoglycans|Myoclonus|Psychiatric Disorders|Prevalence|Quality of Life|Mutation 208 SGCE 31639302 ACS Appl Mater Interfaces 2019 PMC6858527 10.1021/acsami.9b14670 2 0 0 160 FN1 protein, human|*Fibronectins|*Graphite|Tissue Engineering|*Cell Differentiation|Chondrogenesis|Chondrocytes|Tissue Scaffolds|Extracellular Matrix|*Cell-Matrix Junctions|Cell Culture|Stress, Mechanical|Cell Adhesion|Cells, Cultured|Extracellular Matrix Proteins 208 SGCE 31571302 Mov. Disord. 2019 10.1002/mds.27857 0 0 0 160 *Myoclonus|Myoclonic dystonia|*Dystonic Disorders|Sarcoglycans|*Sensation|Dystonia 208 SGCE 31423828 Orv Hetil 2019 10.1556/650.2019.31472 0 0 0 160 Myoclonic dystonia|*Zonisamide|*Dystonic Disorders|Sarcoglycans|Myoclonus|Dystonia|Mutations 208 SGCE 31413899 Tremor Other Hyperkinet Mov (N Y) 2019 PMC6691910 10.7916/tohm.v0.656 0 0 0 160 Myoclonic dystonia|*Dystonic Disorders|Sarcoglycans|Myoclonus|Dystonia|Phenotype|Mutation|Gait 208 SGCE 31392249 Mov Disord Clin Pract 2019 PMC6660223 10.1002/mdc3.12805 0 0 0 160 Myoclonic dystonia|Dystonic Disorders|Sarcoglycans|Myoclonus|Pedigree|Exons|Mutation 208 SGCE 31315643 J. Exp. Clin. Cancer Res. 2019 PMC6637527 10.1186/s13046-019-1318-5 3 1 0 160 *Stomach Neoplasms|Kynurenine|Tryptophan|Indoleamine-Pyrrole 2,3,-Dioxygenase|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Tumor Microenvironment 208 SGCE 30849405 Neurosci. Lett. 2019 10.1016/j.neulet.2019.03.003 0 0 0 160 Humans|Myoclonic dystonia|Dystonia 12|*Familial Dystonia|epsilon-Sarcoglycan|*Mutations|Myoclonus|Phenotype|SGCE protein, human 208 SGCE 30643666 Tremor Other Hyperkinet Mov (N Y) 2019 PMC6329780 10.7916/D8H438GS 3 0 0 160 Humans|*Risk Factors|*Dystonic Disorders|*Dystonia|Molecular Chaperones|Nuclear Proteins|Genetic Predisposition to Disease|DNA-Binding Proteins|Single Nucleotide Polymorphisms|GTP-Binding Protein alpha Subunits|Mutation|Apoptosis Regulatory Proteins 208 SH3TC2 31827005 Neurology 2019 PMC7011687 10.1212/WNL.0000000000008672 0 0 0 139 *Charcot-Marie-Tooth Disease|Myelin P0 Protein|*Sequencing, Next-Generation|Genetic Testing|Connexins|Gene Duplication|Genotype|Gene Deletion|Demyelinating Diseases 77 SH3TC2 31790684 Brain Res. 2019 10.1016/j.brainres.2019.146572 1 1 0 139 Tissue Distribution|Charcot-Marie-Tooth disease, Type 4C|Charcot Marie Tooth Disease|*Schwann Cells|Myelin|Demyelinating Diseases|Mutations|Axons|*Gene Therapy 77 SH3TC2 31634715 J. Neurol. Sci. 2019 10.1016/j.jns.2019.06.027 0 0 0 139 Humans|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|*Scoliosis|Phenotype|Mutation|Pedigree|Inherited Peripheral Neuropathy|Genotype|Mutation, Missense|Proteins|Codon, Nonsense|Hearing Loss|Cohort Studies|SH3TC2 protein, human 77 SH3TC2 31393079 Mol Genet Genomic Med 2019 PMC6732311 10.1002/mgg3.839 1 0 0 139 Inherited Peripheral Neuropathy|*Hearing Loss|*Deafness|Charcot Marie Tooth Disease|Phenotype|Genetic Testing|Genotype|Pedigree|Mutation 77 SH3TC2 31346473 Cerebellum Ataxias 2019 PMC6631598 10.1186/s40673-019-0103-8 1 0 0 139 Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|*Phenotype|*Cerebellum|Mutation|Proteins|Ataxia, Friedreich|Scandinavia|Southern Europe 77 SH3TC2 31227790 J. Hum. Genet. 2019 10.1038/s10038-019-0636-y 0 0 0 139 Humans|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|*Mutations|*Heterozygote|Genetic Testing|Proteins|Phenotype|Scoliosis|*Corticosterone|Japan|SH3TC2 protein, human 77 SH3TC2 30907403 Brain 2019 PMC6487329 10.1093/brain/awz064 3 0 0 139 Humans|Mice|Animals|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|Schwann Cells|Myelin|*Genetic Therapy|Sciatic Nerves|Connexins|rab11 protein|rab GTP-Binding Proteins|Disease Models, Animal|Mutations|Gene Expression|Phenotype|Sh3tc2 protein, mouse|Carrier Proteins 77 SH3TC2 30658898 Neuromuscul. Disord. 2019 10.1016/j.nmd.2018.11.010 1 0 0 139 Male|Humans|Child|Child, Preschool|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|Phenotype|Genetic Testing|Mutation|Proteins|*Muscular Diseases|Mutation, Missense 77 SH3TC2 30653784 J. Peripher. Nerv. Syst. 2019 10.1111/jns.12305 0 0 0 139 Humans|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|Greece|*Mutations|Genetic Testing|Pedigree|Phenotype|Proteins|Genotype|SH3TC2 protein, human 77 Six5 31853004 Cell Res. 2019 PMC7015062 10.1038/s41422-019-0264-2 0 0 0 112 Animals|Mice|*Myotonic Dystrophy|Myotonin-Protein Kinase|Trinucleotide Repeat Expansion|Muscle, Skeletal|Phenotypes|RNA, Messenger|Genes, Homeobox 113 Six5 31840338 Mol. Reprod. Dev. 2019 10.1002/mrd.23307 1 0 0 112 Humans|Male|*Myotonic Dystrophy|Myotonin-Protein Kinase|Trinucleotide Repeat Expansion|Muscle, Skeletal|Homeodomain Proteins|*Biomarkers 113 slamf8 31213836 Onco Targets Ther 2019 PMC6549391 10.2147/OTT.S198762 2 0 0 45 19 slamf8 30873760 Cancer Med 2019 PMC6488129 10.1002/cam4.2055 2 1 0 45 Humans|*Stomach Neoplasms|Early Detection of Cancer|Prognosis|Biomarkers, Tumor|Neoplasm Staging|Proteomics|ELISA|somatotropin-binding protein|Carrier Proteins 19 SMCHD1 31794465 Continuum (Minneap Minn) 2019 10.1212/CON.0000000000000801 1 0 0 145 Adult|Humans|Child|*Muscular Dystrophy, Facioscapulohumeral|Epigenesis, Genetic|Chromosomal Proteins, Non-Histone|Phenotype|Homeodomain Proteins 121 SMCHD1 31676591 J. Med. Genet. 2019 10.1136/jmedgenet-2019-106402 1 0 0 145 Facio-Scapulo-Humeral Dystrophy|Chromatin|*Introns|Chromosomal Proteins, Non-Histone|Epigenesis, Genetic|DNA Methylation|Homeodomain Proteins|Muscle, Skeletal|Mutation 121 SMCHD1 31668908 Trends Genet. 2019 PMC6884149 10.1016/j.tig.2019.10.001 2 0 0 145 Humans|Female|Adult|X Chromosome Inactivation|Chromosomal Proteins, Non-Histone|Embryonic Development|Genome|Protein Domain|SMCHD1 protein, human 121 SMCHD1 31600781 Hum. Mol. Genet. 2019 PMC6969370 10.1093/hmg/ddz239 3 0 0 145 Humans|*Muscular Dystrophy, Facioscapulohumeral|Chromosomal Proteins, Non-Histone|DNA Methylation|Mutation|Pedigree|Exons|Homeodomain Proteins|ATPase|SMCHD1 protein, human 121 SMCHD1 31420322 Genetics 2019 PMC6781896 10.1534/genetics.119.302600 0 1 0 145 Humans|Mice|Animals|Choanal Atresia|*X Chromosome Inactivation|Muscular Dystrophy, Facioscapulohumeral|*Gene Expression Regulation|Microphthalmos|Chromosomal Proteins, Non-Histone|DNA Methylation|Mutation|Nose|Mutation, Missense|*Chromosome|Gene Silencing|SMCHD1 protein, human 121 SMCHD1 31365290 Am. J. Physiol., Cell Physiol. 2019 PMC6850993 10.1152/ajpcell.00116.2019 3 0 0 145 Mice|Animals|*Genome|Embryonic Development|Blastocyst|Zygote|Gene Expression Regulation, Developmental|Chromosomal Proteins, Non-Histone|Embryo, Mammalian|Chromatin|Transcription Factors|Oocytes 121 SMCHD1 31316120 Sci Rep 2019 PMC6637155 10.1038/s41598-019-46861-x 0 0 0 145 Humans|Facioscapulohumeral muscular dystrophy 1a|Facioscapulohumeral Muscular Dystrophy 1B|*Muscular Dystrophy, Facioscapulohumeral|Homeodomain Proteins|Mutation|Chromatin 121 SMCHD1 31312724 Commun Biol 2019 PMC6620310 10.1038/s42003-019-0499-y 2 1 0 145 Humans|*ATPase|Muscular Dystrophy, Facioscapulohumeral|Chromosomal Proteins, Non-Histone|UBB protein, human|*Ubiquitin|Amino Acid Sequence|Mutation|SMCHD1 protein, human 121 SMCHD1 31270318 Nat Commun 2019 PMC6610634 10.1038/s41467-019-10755-3 5 1 0 145 *X Chromosome|X Chromosome Inactivation|*RNA, Long Noncoding|Histones|Polycomb Repressive Complex 1|Lysine|Embryonic Stem Cells|HNRNPK protein, human|Heterogeneous-Nuclear Ribonucleoprotein K|DNA Methylation 121 SMCHD1 31243061 J. Med. Genet. 2019 PMC6800092 10.1136/jmedgenet-2019-106168 3 1 0 145 Arhinia, choanal atresia, and microphthalmia|Facioscapulohumeral Muscular Dystrophy 1B|*Muscular Dystrophy, Facioscapulohumeral|*Choanal Atresia|*Microphthalmos|*Nose|*Mutation|Chromosomal Proteins, Non-Histone|*Protein Domain|Phenotype|DNA Methylation|Mutation, Missense|Adenosine Triphosphatases 121 SMPX 31583691 Ann. Hum. Genet. 2019 10.1111/ahg.12350 2 0 0 17 *Single Nucleotide Polymorphisms|*In Silico|Bioinformatics|Protein Conformation|Software|Databases, Genetic|Mutations|Mutant Proteins|Models, Molecular|Nucleotides 41 SMPX 31478598 Mol Genet Genomic Med 2019 PMC6825843 10.1002/mgg3.967 2 0 0 17 Male|Humans|Infant, Newborn|*Donor Site, Splice|*Whole Exome Sequencing|Deafness, X-Linked 4|*Hearing Loss, Sensorineural|*Deafness|*Genes, X-Linked|Genetic Diseases, X-Linked|Pedigree|Hearing Loss|*Polymorphism, Single Nucleotide|Frameshift Mutation|RNA Splicing|Asian Continental Ancestry Group|Muscle Proteins|SMPX protein, human 41 SMPX 30874365 Anat Rec (Hoboken) 2019 10.1002/ar.24115 0 0 0 17 Humans|Animals|*Zebrafish|*Genes, X-Linked|Quality of Life|Nonsyndromic sensorineural hearing loss|*Hearing Loss, Sensorineural|PRPS1 protein, human|Ribose-Phosphate Pyrophosphokinase|Deafness, X-Linked 1|*Genetic Diseases, X-Linked|Nonsyndromic Deafness|Deafness|Hearing Loss|Ear, Inner|Mutations|Pedigree|Mutations, Missense|Phenotype|Hearing 41 SMPX 30618656 Front Syst Neurosci 2019 PMC6305622 10.3389/fnsys.2018.00063 3 0 0 17 Mice|Animals|*Hyperalgesia|*Trigeminal Ganglion|*Nucleus Accumbens|*Gene Regulatory Networks|*Migraine|Nitroglycerin|Pain|Calcitonin Gene-Related Peptide|Vasodilator Agents|Disease Models, Animal|Proto-Oncogene Proteins c-fos 41 SNX14 31733263 Biochim Biophys Acta Mol Cell Res 2019 10.1016/j.bbamcr.2019.118603 0 0 0 37 *Lipid Droplets|*Endoplasmic Reticulum|GTP-Binding Protein gamma Subunits|*Mitochondrial Membranes|Membrane Proteins 22 SNX14 31517839 Medicine (Baltimore) 2019 PMC6750333 10.1097/MD.0000000000017100 0 0 0 37 *Squamous Cell Carcinoma of Head and Neck|*Tongue Neoplasms|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Computational Biology|Transcriptome|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Head and Neck Neoplasms 22 SNX14 30886057 J. Cell Biol. 2019 PMC6446839 10.1083/jcb.201902160 2 1 0 37 *Lipid Droplets|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Endoplasmic Reticulum|GTP-Binding Protein gamma Subunits|Lipid Metabolism|Mitochondrial Membranes|Membrane Proteins|Intermediate Filament Proteins 22 SNX14 30765438 J. Cell Biol. 2019 PMC6446855 10.1083/jcb.201808133 9 2 0 37 *Lipid Droplets|*Cerebellar Ataxia|*Endoplasmic Reticulum|GTP-Binding Protein gamma Subunits|Saccharomyces cerevisiae|Sorting Nexin|Acids, Fatty|Triglycerides|Homeostasis|Protein Sorting 22 SPATA5 31838782 Andrology 2019 10.1111/andr.12742 0 0 0 119 Humans|Male|Mice|Animals|*DNA Methylation|*B-DNA|*Spermatogenesis|Infertility, Male|Oligospermia|CpG Islands|Spermatozoa|Fertility|Promoter Regions, Genetic 19 SPATA5 31807642 Arch Anim Breed 2019 PMC6853132 10.5194/aab-62-313-2019 0 1 0 119 Sheep|Animals|*Parasites|Burkina Faso|*Intestinal Diseases, Parasitic|Sheep Diseases|Parasite Egg Count|*Phenotypes|Quantitative Trait Loci|*Genomics|Single Nucleotide Polymorphisms|Hematocrit|Feces 19 SPATA5 31703473 Biomolecules 2019 PMC6920918 10.3390/biom9110715 2 0 0 119 *AAA ATPases|*Ribosome|Ribosome Subunits, Large, Eukaryotic|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Ribosomal Proteins|Adenosine Triphosphatases|Nuclear Proteins|*Eukaryotic Cells 19 SPATA5 31575436 Epilepsy Res. 2019 10.1016/j.eplepsyres.2019.106211 1 0 0 119 Child|Humans|*Drug Resistant Epilepsy|rufinamide|*Retrospective Studies|*Triazoles|Epilepsy|Lennox Gastaut Syndrome|Anticonvulsants|Treatment Outcome|*Phenotype|*Genotype 19 SPATA5 30984241 Front Genet 2019 PMC6448050 10.3389/fgene.2019.00251 0 0 0 119 Animals|*Ictaluridae|*Chromosome Mapping|Genetic Linkage|Quantitative Trait Loci|*Phenotype|Microsatellite Repeats|Sequence Analysis, DNA|Polymorphism, Single Nucleotide|Aquiculture|*Biological Phenomena 19 TANGO2 31561563 Cancers (Basel) 2019 PMC6827003 10.3390/cancers11101438 0 1 0 104 Humans|Dogs|Animals|Mice|*Methotrexate|*B Cell Lymphoma|*HLA-DR Antigens|Antibodies, Monoclonal|Antibody-Dependent Cell Cytotoxicity|Immunoconjugates|Immunotherapy|Leukemia|Caspase-Dependent Apoptosis|Cell Line, Tumor|Immunoglobulin G 23 TANGO2 31426483 Nanomaterials (Basel) 2019 PMC6724117 10.3390/nano9081179 0 0 0 104 *Semiconductors|*Color|Fluorescence 23 TANGO2 31339582 J. Inherit. Metab. Dis. 2019 PMC7078914 10.1002/jimd.12156 2 0 0 104 Humans|*Proteomics|*Mutations|coenzyme Q10|Coenzyme Q|Homozygote|Exons|Phenotype|Muscle Weakness|Rhabdomyolysis|Mitochondria|Arrhythmias, Cardiac 23 TANGO2 31276219 J. Inherit. Metab. Dis. 2019 10.1002/jimd.12149 1 0 0 104 Humans|Child|Adolescent|*Mitochondria|Phenotype|Intellectual Disability|Homozygote|Whole Exome Sequencing|Exome|Pedigree|Mutations|Exons|Ataxia|*Nervous System Malformations|*Energy Metabolism|Cardiac Arrhythmias|Cerebellar Ataxia 23 TANGO2 30890123 BMC Genomics 2019 PMC6425649 10.1186/s12864-019-5531-6 1 0 0 104 Humans|Dogs|Animals|Osteosarcoma|Bone Neoplasms|Dog Diseases|DNA Copy Number Variations|*Multifactorial Inheritance|Genetic Predisposition to Disease|Disease Models, Animal 23 TANGO2 30650451 Neuropediatrics 2019 10.1055/s-0038-1677514 2 0 0 104 Humans|Female|Child|Adolescent|Alternating hemiplegia of childhood|*Hemiplegia|*Homozygote|*Phenotype|Sequencing, Whole Exome|Sodium-Potassium-Exchanging ATPase|Epilepsy|Mutation|*Nucleotides 23 TANGO2 30646572 Micromachines (Basel) 2019 PMC6356254 10.3390/mi10010053 0 0 0 104 *Polymer|polystyrene sulfonic acid|Polystyrenes|Electric Conductivity|Atomic Force Microscopy|Temperature 23 TBR1 31699123 Mol Brain 2019 PMC6836402 10.1186/s13041-019-0507-7 0 0 0 196 Humans|Male|Adolescent|*Autistic Disorder|Autism Spectrum Disorder|*Memory|*Neurogenesis|Induced Pluripotent Stem Cells|Neurons|Cell Differentiation|Excitatory Postsynaptic Currents|Aptitude|Cognition|*Intellectual Disability 267 TBR1 31478734 Onderstepoort J. 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Res. 2019 PMC6739528 10.4102/ojvr.v86i1.1638 0 0 0 196 Female|Male|Mice|Animals|*Trypanosoma|Trypanosomiasis|Camel|DNA Primers|DNA, Protozoan|Polymerase Chain Reaction|Parasitemia|Egypt 267 TBR1 31427988 Front Physiol 2019 PMC6688582 10.3389/fphys.2019.00990 0 0 0 196 Infant, Newborn|Humans|Animals|Sheep|*Caffeine|*Cerebellum|*Telencephalon|*Sheep, Domestic|Apnea|Brain|Gestational Age|Infant, Premature, Diseases|*Cerebrum 267 TBR1 31378057 Ann Parasitol 2019 10.17420/ap6502.196 0 0 0 196 Animals|Female|Male|*Camelus|Iran|*Trypanosoma|Trypanosomiasis|DNA, Protozoan|PCR|Antibodies, Protozoan|Prevalence 267 TBR1 31363137 Sci Rep 2019 PMC6667451 10.1038/s41598-019-47444-6 3 0 0 196 Humans|*Microglia|Human Induced Pluripotent Stem Cells|*Brain|Amyloid beta-Peptides|Cell Culture Techniques|Organoids|Phagocytosis|Cells, Cultured|Lipopolysaccharides|Co-culture|Cytokines 267 TBR1 31227709 Nat Commun 2019 PMC6588589 10.1038/s41467-019-10765-1 3 0 0 196 Animals|Child|Humans|Adolescent|Adult|*Neural Stem Cells|*Amygdala|Neurogenesis|Neurons|Hippocampus|polysialyl neural cell adhesion molecule|Neural Cell Adhesion Molecule L1|Paralaminar Nucleus|Neuronal Plasticity|Sialic Acids|Interneurons 267 TBR1 31203451 Brain Struct Funct 2019 PMC6698271 10.1007/s00429-019-01906-9 0 0 0 196 Animals|*Olfactory Bulb|*Sharks|*Neurogenesis|Paired Box Transcription Factors|Neural Stem Cells|Homeodomain Proteins|Cell Differentiation|Eye Proteins|PAX6 Transcription Factor|Repressor Proteins|Neurons|Cell Proliferation|*Hematopoiesis 267 TBR1 31202705 Neuroscience 2019 10.1016/j.neuroscience.2019.05.062 2 0 0 196 Pregnancy|Female|Mice|Animals|*Ependymoglial Cells|JAG1 protein, human|*Jagged-1 Protein|Neural Stem Cells|Neurogenesis|Neocortex|Receptors, Notch|Cell Differentiation|Signal Transduction|Astrocytes 267 TBR1 31142819 Mol. Psychiatry 2019 10.1038/s41380-019-0436-y 1 0 0 196 Animals|Mice|*Proteomics|*Schizophrenia|*Neurons|Transcription Factor, TCF-4|Genome-Wide Association Study|*Phenotypes|Genetic Predisposition to Disease|Multifactorial Inheritance|Synapse|Synaptic Transmission|Signal Transduction 267 TGM6 30884206 Cancer Med 2019 PMC6536975 10.1002/cam4.2071 6 0 0 55 Humans|*Colon Cancer|Prognosis|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Bioinformatic|Protein Interaction Maps|Kaplan-Meier Estimate|Transcriptome|Neoplasm Staging|ROC Curve|Survival Analysis|Transcription Factors|PNMA5 protein, human|Antigens, Neoplasm 22 TGM6 30670339 Parkinsonism Relat. Disord. 2019 10.1016/j.parkreldis.2019.01.013 3 0 0 55 Humans|*Spinocerebellar Ataxias|Mutations|Pedigree|Asians|Transglutaminases|Phenotypes|Cohort Studies 22 tmem127 31781416 Case Rep Endocrinol 2019 PMC6855059 10.1155/2019/2502174 1 0 0 146 Pheochromocytoma|Adrenal Gland Neoplasms|Paragangliomas|Germ-Line Mutation|Membrane Proteins 111 tmem127 31772663 J Cancer 2019 PMC6856753 10.7150/jca.33250 0 0 0 146 111 tmem127 31705439 Endocr. Pathol. 2019 10.1007/s12022-019-09594-1 0 0 0 146 Middle Aged|Male|Humans|*Paraganglioma|Pheochromocytomas|Adrenal Gland Neoplasms|Succinate Dehydrogenase|Mutations, Germline|*Mutations|Neoplastic Syndromes, Hereditary|Genetic Testing|Heterozygote|*Pelvis, Renal|Membrane Proteins|ATRX protein, human|X-linked Nuclear Protein|SDHB protein, human 111 tmem127 31666924 Oncotarget 2019 PMC6800268 10.18632/oncotarget.27194 0 0 0 146 Humans|*Paraganglioma|Pheochromocytoma|Adrenal Gland Neoplasms|*Genotype-Phenotype Correlation|Mutations, Germline|Succinate Dehydrogenase|*Mutations|Genetic Testing|Genetic Predisposition to Disease|Membrane Proteins|Phenotype|Saudi Arabia 111 tmem127 31624249 Nat Commun 2019 PMC6797792 10.1038/s41467-019-12661-0 1 4 0 146 Humans|Mice|Animals|*Insulin Resistance|Diet, High-Fat|Obesity|Adiposity|Adipogenesis|Liver|Steatohepatitis|Glucose|Gluconeogenesis|Adipose Tissue|Mice, Knockout|Homeostasis|Diet, Fat-Restricted|Insulin|Hepatocytes|Mice, Inbred C57BL|*Genes, Tumor Suppressor|TMEM127 protein, human 111 tmem127 31307198 Neoplasma 2019 PMC6826254 10.4149/neo_2018_181208N933 1 0 0 146 *Paragangliomas|SDHD protein, human|Succinate Dehydrogenase|Pheochromocytoma|*Paragangliomas, Extra-Adrenal|Adrenal Gland Neoplasms|*Genetic Testing|*Head and Neck Neoplasms|Germ-Line Mutation|Neurofibromatosis Type I|Mutations|Genetic Predisposition to Disease|Membrane Proteins|Phenotype|Longitudinal Studies 111 tmem127 31046099 J. Clin. Endocrinol. Metab. 2019 10.1210/jc.2019-00175 0 0 0 146 *Paraganglioma|*Germline Mutation|Succinate Dehydrogenase|Pheochromocytoma|Adrenal Gland Neoplasms|*Phenotype|Heterozygote|Genotype|Head and Neck Neoplasms|Membrane Proteins|Germ Line 111 TRIB1 31692955 Sci Adv 2019 PMC6821468 10.1126/sciadv.aax9183 1 3 0 410 Mice|Animals|*Foam Cells|*Atherosclerosis|Atherosclerotic Plaque|Lipoproteins, LDL|Apolipoproteins E|Cholesterol|CD36 Antigens|Macrophages|Inflammation Mediators|Disease Models, Animal 198 TRIB1 31688456 Curr. Opin. Hematol. 2019 10.1097/MOH.0000000000000552 0 0 0 410 *Eosinophils|Transcription Factors|*Cytokines|Cell Lineage|GATA1 Transcription Factor|Cell Differentiation|Erythroid-Specific DNA-Binding Factors|*Complement Factor B|3'-(1-butylphosphoryl)adenosine 198 TRIB1 31666640 Sci Rep 2019 PMC6821852 10.1038/s41598-019-52253-y 0 5 0 410 Humans|Mice|Animals|*Berberine|*Upregulation|LDLR protein, human|*LDL Receptor|Hypercholesterolemia|*Liver|LDL Cholesterol|Hyperlipidemias|Cholesterol|Triglycerides|Hypolipidemic Agents|*Transcriptional Activation|TRIB1 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins 198 TRIB1 31621188 FEBS J. 2019 10.1111/febs.15096 0 0 0 410 Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|Cell Cycle Proteins|Signal Transduction|Cell Differentiation|Cell Cycle|Cancer 198 TRIB1 31470861 Lipids Health Dis 2019 PMC6717352 10.1186/s12944-019-1108-2 1 0 0 410 Humans|*Non-alcoholic Fatty Liver Disease|*Asian Continental Ancestry Group|*Coronary Heart Disease|Gene Frequency|Genetic Association Studies|Polymorphism, Single Nucleotide|Intracellular Signaling Peptides and Proteins|Protein-Serine-Threonine Kinases|Triglycerides|Genotype|Case-Control Studies|Lipids|TRIB1 protein, human 198 TRIB1 31423579 Br. J. Haematol. 2019 10.1111/bjh.16158 0 6 0 410 Humans|Mice|Animals|*Lenalidomide|*Multiple Myeloma|JAK1 protein, human|*Janus Kinase 1|CXCL12 protein, human|*Chemokine CXCL12|*Macrophage Activation|CXCR4 protein, human|*Receptors, CXCR4|*Signal Transduction|Macrophages|TRIB1 protein, human|Intracellular Signaling Peptides and Proteins|Monocytes|CD44 protein, human|*Hyaluronan Receptors|Janus Kinases|Protein-Serine-Threonine Kinases 198 TRIB1 31250580 Yonsei Med. J. 2019 PMC6597471 10.3349/ymj.2019.60.7.659 1 0 0 410 Humans|Gene Frequency|Polymorphism, Single Nucleotide|Intracellular Signaling Peptides and Proteins|Asian Continental Ancestry Group|Genetic Association Studies|Genotype|Protein-Serine-Threonine Kinases|Triglycerides|Case-Control Studies 198 TRIB1 31196602 Curr Top Membr 2019 10.1016/bs.ctm.2019.01.006 0 0 0 410 Animals|*Transcriptome|*Rodent|Ouabain|Sodium|Potassium|Sodium-Potassium-Exchanging ATPase|Transcription, Genetic|Muscle, Smooth, Vascular|Calcium|Signal Transduction|Cells, Cultured|Ions|Cations, Monovalent 198 TRIB1 31191752 Dis. Markers 2019 PMC6525907 10.1155/2019/5631083 1 0 0 410 Genome-Wide Association Study|Neurodegenerative Diseases|Age Related Macular Degeneration|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Collagen Type VIII|Genotype|Retina|Case-Control Studies 198 TRIB1 31018662 Arterioscler. Thromb. Vasc. Biol. 2019 PMC6761832 10.1161/ATVBAHA.118.311573 0 0 0 410 Humans|Genome-Wide Association Study|Lipid Metabolism|Intracellular Signaling Peptides and Proteins|Protein-Serine-Threonine Kinases|Lipogenesis|Liver|Triglycerides|Hepatocytes|Lipids|Hep G2 Cells|RNA, Messenger|Coronary Artery Disease 198 TRIB1 30926388 Cell. Signal. 2019 10.1016/j.cellsig.2019.03.017 1 4 0 410 Humans|Male|*Macrophages|NFKBIZ protein, human|*I-kappa B Proteins|Macrophage Activation|CD163 antigen|Antigens, Differentiation, Myelomonocytic|THP-1 Cells|PC3 Cells|*Prostate Cancer|Signal Transduction|Cytokines|*Nuclear Proteins|Receptors, Cell Surface|CXCL8 protein, human|Interleukin-8|Medium, Conditioned|*Phenotype|Cell Differentiation 198 TRIB1 30917956 Blood 2019 PMC6543518 10.1182/blood.2018872218 2 2 0 410 Mice|Animals|*Eosinophils|*Neutrophils|Hematopoietic Stem Cells|Cell Lineage|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|Cell Differentiation|CCAAT-Enhancer-Binding Protein-alpha|Mice, Knockout 198 TRIB1 30851741 Lipids Health Dis 2019 PMC6408849 10.1186/s12944-019-1001-z 3 0 0 410 Humans|*Non-alcoholic Fatty Liver Disease|*Asian Continental Ancestry Group|Gene Frequency|Polymorphism, Single Nucleotide|Triglycerides|Genotype|Intracellular Signaling Peptides and Proteins|Genetic Association Studies|Protein-Serine-Threonine Kinases|Lipid Metabolism|Case-Control Studies|Lipids|Risk Factor|TRIB1 protein, human 198 TSPEAR 31595324 Cancer Immunol. Immunother. 2019 10.1007/s00262-019-02401-0 1 0 0 2 Humans|*T Cell Receptor|*T-Cell Receptor Gene|T-Cell Specificity|Immunotherapy, Adoptive|Receptors, Antigen, T-Cell, alpha-beta|*Cross Reactions|Cytotoxicity, Immunologic|HLA-A2 Antigen|Jurkat Cells|*Immunotherapy|*Antibody Specificity 19 TSPEAR 31367490 PeerJ 2019 PMC6657684 10.7717/peerj.7380 2 0 0 2 lncRNA|*Laryngeal Neoplasms|miRNAs|Gene Regulatory Networks|RNA, Messenger|Prognosis|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Transcriptome|Biomarkers, Tumor|Kaplan-Meier Estimate|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms 19 TSPEAR 30989713 J. Cell. Biochem. 2019 10.1002/jcb.28655 8 0 0 2 Humans|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|MicroRNAs|mRNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Ontology|Kaplan-Meier Estimate|Receiver Operating Characteristic|TSPEAR protein, human|Proteins 19 TSPEAR 30755833 PeerJ 2019 PMC6368841 10.7717/peerj.6397 7 21 0 2 *RNA, Long Noncoding|MicroRNAs|*Tongue Neoplasms|Gene Regulatory Networks|*Squamous Cell Carcinoma of Head and Neck|RNA, Messenger|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|Head and Neck Neoplasms 19 TSPEAR 30742027 Sci Rep 2019 PMC6370815 10.1038/s41598-019-38517-7 7 0 0 2 Humans|*Mesenchymal Stem Cells|*Bone Marrow|NGFR protein, human|Receptors, Nerve Growth Factor|Chondrogenesis|Bone Marrow Cells|Osteogenesis|Cell Differentiation|Adipogenesis|Nerve Tissue Proteins|CXCL12 protein, human|Chemokine CXCL12|CD271|CCN5 protein, human|CCN Intercellular Signaling Proteins|Cells, Cultured|CCN4 protein, human|Cell Proliferation 19 TXNDC12 31570854 Cell Death Differ. 2019 PMC7206186 10.1038/s41418-019-0421-7 3 6 0 67 Humans|*Epithelial-Mesenchymal Transition|*Carcinoma, Hepatocellular|*Liver Neoplasms|beta Catenin|*Catenins|Wnt Signaling Pathway|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|Upregulation|Biomarkers, Tumor|Cell Line, Tumor 19 TXNDC12 31368601 EMBO J. 2019 PMC6670016 10.15252/embj.2018100990 9 4 0 67 *Unfolded Protein Response|Activating Transcription Factor 6|Endoplasmic Reticulum|X-Box Binding Protein 1|Endoplasmic Reticulum Stress|Golgi Apparatus|Transcription Factor|Signal Transduction|Protein Transport|Membrane Proteins|Gene Activation|Gene Expression Regulation|Proteolysis 19 UNC13A 31624333 Pharmacogenomics J. 2019 10.1038/s41397-019-0111-3 1 4 0 276 Humans|*Amyotrophic Lateral Sclerosis|*Pharmacogenetics|DNA Repeat Expansion|C9orf72 Protein|*Pharmacogenomic Testing|Heterozygote|Genotype|Proteins|Mutation|C9orf72 protein, human 88 UNC13A 31535974 Elife 2019 PMC6752948 10.7554/eLife.43243 0 0 0 276 *Synaptic Vesicles|Synapses|Synaptic Transmission|Mossy Fibers, Hippocampal|Hippocampus|Patch-Clamp Techniques|Nerve Tissue Proteins|Intracellular Signaling Peptides and Proteins 88 UNC13A 31243993 Biochemistry 2019 PMC6620733 10.1021/acs.biochem.9b00427 0 3 0 276 Mice|Animals|bryostatin 1|*Bryostatins|UNC13B protein, human|*Nerve Tissue Proteins|Synaptic Transmission|Synaptic Vesicles|Phorbol Esters|Protein Kinase C|Binding Sites|Protein Domain 88 UNC13A 31201598 Neurol. Sci. 2019 10.1007/s10072-019-03951-y 2 0 0 276 Humans|*Amyotrophic Lateral Sclerosis|Neurodegenerative Diseases|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Nerve Tissue Proteins|Allele|Genotype 88 UNC13A 31173847 Neurosci. Lett. 2019 10.1016/j.neulet.2019.03.048 7 0 0 276 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Genome-Wide Association Study|Neurodegenerative Diseases|*Extracellular Vesicles|MicroRNAs|Circulating MicroRNA|Downregulation|Biomarkers|Disease Progression|Up-Regulation|*Plasma|*Neurons 88 UNC13A 31044425 Clin. Genet. 2019 10.1111/cge.13558 0 0 0 276 Humans|*Hydroxymethylbilane Synthase|*Porphyria, Acute Intermittent|*Penetrance|*Mutations|Porphyrias|Russia|SCN4A protein, human|NAV1.4 Voltage-Gated Sodium Channel|DOK7 protein, human|Muscle Proteins 88 UNC13A 30941097 Front Neurol 2019 PMC6433874 10.3389/fneur.2019.00257 1 5 0 276 *Myasthenic Syndromes, Congenital|Neuromuscular Junction|Synaptic Transmission|*Electrophysiological Phenomena|Presynaptic Terminal|Acetylcholine|Muscle Weakness|Mutations|Synaptic Vesicles 88 UNC13A 30894602 Sci Rep 2019 PMC6427022 10.1038/s41598-019-41259-1 3 2 0 276 Humans|*Neurons|Potential, Action|Synaptic Transmission|Neurogenesis|Induced Pluripotent Stem Cells|Patch-Clamp Techniques|Neural Stem Cells|Hippocampus|Cells, Cultured|Cell Differentiation 88 UNC13A 30816091 Elife 2019 PMC6407922 10.7554/eLife.42806 6 13 0 276 *Synaptic Transmission|Synaptic Vesicles|Nerve Tissue Proteins|Neurotransmitter Agents|*Biological Transport|Neurons|Intracellular Signaling Peptides and Proteins|Cells, Cultured|*Membrane 88 UNC13A 30739198 Acta Neuropathol. 2019 PMC6533145 10.1007/s00401-019-01962-9 11 0 0 276 Humans|*Frontotemporal Dementia|*Genome-Wide Association Study|*Risk Factors|*FTLD|TDP-43 Proteinopathies|Progranulins|Mutations|Inclusion Bodies|DNA-Binding Proteins|*Sequencing, Whole Genome|Neurons|Cohort Studies|C9orf72 protein, human|C9orf72 Protein 88 UNC13A 30622273 Nat Commun 2019 PMC6325239 10.1038/s41467-018-08028-6 11 1 0 276 SNAP25 protein, human|Synaptosomal-Associated Protein 25|*Membrane Fusion|UNC13B protein, human|*Nerve Tissue Proteins|Munc18 Proteins|Synaptobrevin 2|Syntaxin 1|Exocytosis|*Neurons|Syntaxin|Protein Binding|*Biological Transport 88 USB1 31832688 Nucleic Acids Res. 2019 PMC7026655 10.1093/nar/gkz1177 0 0 0 66 Humans|U6 small nuclear RNA|Saccharomyces cerevisiae|*Exoribonucleases|*RNA, Small Nuclear|Spliceosomes|Ribonucleoprotein, U4-U6 Small Nuclear|Saccharomyces cerevisiae Proteins|RNA Splicing|Active Site|Nucleic Acid Conformation|Phosphoric Diester Hydrolases|Models, Molecular|Protein Domains|USB1 protein, human 34 USB1 31522452 Iran J Allergy Asthma Immunol 2019 10.18502/ijaai.v18i4.1424 0 0 0 66 Male|Humans|Infant|Poikiloderma with Neutropenia|Iran|*Skin Abnormalities|*Neutropenia|Mutation|Phosphoric Diester Hydrolases|DNA Sequence 34 USB1 31311495 BMC Infect. Dis. 2019 PMC6636094 10.1186/s12879-019-4244-4 2 0 0 66 *Latent Tuberculosis|*Cross-Sectional Studies|*Nutritional Status|*Diabetes Mellitus|Tuberculosis|Body Mass Index|Prevalence|Risk Factors 34 USB1 31271354 Elife 2019 PMC6660216 10.7554/eLife.46477 3 0 0 66 Humans|*Diabetes Mellitus|Pulmonary Tuberculosis|Antitubercular Agents|*Comorbidity|Mycobacterium tuberculosis|Sputum|Cytokines|Treatment Outcome|*Inflammation|India|Risk Factors|Brazil 34 USP9Y 31781421 Case Rep Genet 2019 PMC6874946 10.1155/2019/3802613 0 0 0 19 Humans|Male|Infertility, Male|Spermatogenesis|Azoospermia|Chromosomes, Human, Y|Chromosome Deletion|Minor Histocompatibility Antigens|Fertility 80 USP9Y 31475374 Anim. Genet. 2019 10.1111/age.12841 1 0 0 19 Cattle|Male|Animals|Y Chromosome|Spermatogenesis|Testis|Fertility|Hybridization, Genetic|Phylogeny|RNA, Messenger 80 USP9Y 31402110 Eur J Med Genet 2019 10.1016/j.ejmg.2018.10.012 0 0 0 19 Male|Female|Humans|Infertility, Male|Azoospermia|*Chromosomes B|Chromosomes, Human, Y|Spermatogenesis|Sex Chromosomes|Sex Chromosome Disorders|Phenotypes|Aneuploidies|Sex Determination Analysis|Anorchia|Gonadal Dysgenesis, 46,XY|Testis|PGRMC1 protein, human|Membrane Proteins|Receptors, Progesterone|FMR1 protein, human|Fragile X Mental Retardation Protein 80 USP9Y 31294067 Data Brief 2019 PMC6595415 10.1016/j.dib.2019.104130 0 0 0 19 *Ubiquitin-Specific Proteases|Ubiquitin Thiolesterase|*Transcriptome Profiling|Cell Line, Tumor|Y Chromosomes 80 USP9Y 31171972 Basic Clin Androl 2019 PMC6545630 10.1186/s12610-019-0089-3 0 0 0 19 Humans|Male|*Cryptorchidism|Sexual Maturation|Testes|Spermatogonia|Azoospermia|Infertility, Male|Testosterone|Gonadotropin|*Y Chromosomes|Fertility 80 USP9Y 30760267 Reprod. Biol. Endocrinol. 2019 PMC6375207 10.1186/s12958-019-0465-z 0 0 0 19 Humans|Male|Female|*Endometriosis|*Chimerism|*Endometrium|Infertility, Female|Fertility|*Genomics|*Y Chromosome|Gene Expression 80 VPS13A 31876103 Mol Genet Genomic Med 2019 PMC7057107 10.1002/mgg3.1108 1 0 0 118 Humans|Child|*Spastic Paraplegia, Hereditary|Spastic Ataxia|Optic Atrophy|Spinocerebellar Ataxias|Cohen syndrome|Intellectual Disability|Mutations|Heterozygote|Muscle Spasticity|Phenotypes|Pedigree|Parkinsonism|Developmental Disabilities|Fingers|Microcephaly|Muscle Hypotonia|Myopia|Obesity 113 VPS13A 31543803 Case Rep Neurol 2019 PMC6738267 10.1159/000500951 0 0 0 118 Humans|Male|Adult|*Neuroacanthocytosis|*Deep Brain Stimulation|Neurodegenerative Diseases|Globus Pallidus|Dystonia|Movement, Hyperkinetic|Mutation|Proteins|Dystonic Disorders 113 VPS13A 31451666 Proc. Natl. Acad. Sci. 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Neurosci. 2019 10.31083/j.jin.2019.02.165 0 0 0 118 Neuroacanthocytosis, Mcleod Type|*Neuroacanthocytosis|Neurodegenerative Diseases|Acanthocytes|Huntington Disease-Like 2|Heredodegenerative Disorders, Nervous System|Pantothenate Kinase-Associated Neurodegeneration|Abetalipoproteinemia|Cognition Disorders|Dementia|Red Blood Cells|Magnetic Resonance Imaging|Erythrocyte Count 113 VPS13A 31192303 Neurol Genet 2019 PMC6515943 10.1212/NXG.0000000000000332 0 0 0 118 Neuroacanthocytosis|Vesicular Transport Proteins|Mutations 113 VPS13A 31139485 Case Rep Psychiatry 2019 PMC6500623 10.1155/2019/5947416 1 0 0 118 *Neuroacanthocytosis|Dystonic Disorders|Obsessive Compulsive Disorder|Vesicular Transport Proteins|*Criminal Behavior|Neurologic Examination|Mutation 113 VPS13A 30741634 Elife 2019 PMC6389287 10.7554/eLife.43561 9 13 0 118 Humans|*Lipid Droplets|*Mitochondria|Endoplasmic Reticulum|Mitochondrial Membranes|Vesicular Transport Proteins|Endosomes|VPS13A protein, human 113 VPS13A 30709847 Dis Model Mech 2019 PMC6398486 10.1242/dmm.036681 4 7 0 118 Humans|Neurodegenerative Diseases|*Lysosomes|*Mitochondria|Chorea-Acanthocytosis|Vesicular Transport Proteins|Endosomes|Protein Transport|Autophagy|VPS13A protein, human 113 VPS13A 30687222 Front Neurol 2019 PMC6334619 10.3389/fneur.2018.01168 1 0 0 118 Humans|Adult|*Neuroacanthocytosis|*Epilepsy|Pedigree|Vesicular Transport Proteins|Movement Disorders|Mutations|Magnetic Resonance Imaging 113 VPS13A 30635263 Dis Model Mech 2019 PMC6361151 10.1242/dmm.036830 2 47 0 118 Humans|*Neuroacanthocytosis|*Calmodulin|*Saccharomyces cerevisiae|*Myosin B|Neurodegenerative Diseases|Saccharomyces cerevisiae Proteins|Vesicular Transport Proteins|*Calcium Signaling|Actins|Endocytosis|Cell Membrane 113 VPS13C 31876103 Mol Genet Genomic Med 2019 PMC7057107 10.1002/mgg3.1108 1 0 0 72 Humans|Child|*Spastic Paraplegia, Hereditary|Spastic Ataxia|Optic Atrophy|Spinocerebellar Ataxias|Cohen syndrome|Intellectual Disability|Mutations|Heterozygote|Muscle Spasticity|Phenotypes|Pedigree|Parkinsonism|Developmental Disabilities|Fingers|Microcephaly|Muscle Hypotonia|Myopia|Obesity 43 VPS13C 31836585 Cold Spring Harb Mol Case Stud 2019 PMC6913143 10.1101/mcs.a003491 1 0 0 72 *Alleles|C9orf72 Protein|Alzheimer Disease|Genetic Association Studies|Genetic Predisposition to Disease|*Chromosome Mapping 43 VPS13C 31779813 Int. 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Neurochem. 2019 PMC6707858 10.1111/jnc.14820 4 2 0 72 *Parkinson Disease|*Lysosomes|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|alpha-Synuclein|*Endosomes|Dopaminergic Neurons|Mitophagy|Mitochondria|Autophagy|parkin protein|Ubiquitin-Protein Ligases|Auxilin|Endocytosis|Synaptic Vesicles|Mutations|Protein Transport 43 VPS13C 31277379 Int J Mol Sci 2019 PMC6651490 10.3390/ijms20133284 1 3 0 72 Animals|Mice|microtubule-associated protein 1B|*Microtubule-Associated Proteins|alpha Synuclein|*Synapse|Parkinson Disease|*Brain|Protein Kinases|*Autophagy|Phosphorylation|Disease Models, Animal 43 wdfy1 31015298 J. Exp. Med. 2019 PMC6547865 10.1084/jem.20180861 0 6 0 79 Mice|Animals|*Vascular Endothelial Growth Factor C|Type I Interferons|*Cell Line|Signal Transduction|Interferon Regulatory Factor-3|Adaptor Proteins, Signal Transducing|Macrophages|Mice, Knockout|Mice, Inbred C57BL|Hes1 protein, mouse|Transcription Factor HES-1 19 WDR11 31726455 Neuroendocrinology 2019 10.1159/000504783 0 0 0 50 Male|Humans|Female|Sexual Maturation|*Cohort Studies|Growth Disorders|*Biological Phenomena|Male|Humans|Female|Sexual Maturation|*Cohort Studies|Growth Disorders|*Biological Phenomena 36 WDR11 30738099 Behav. Brain Res. 2019 10.1016/j.bbr.2019.02.010 2 1 0 50 Genome-Wide Association Study|*Attention Deficit Disorder with Hyperactivity|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Schizophrenia|*Brain|Quantitative Trait Loci|Gene Expression 36 WDR11 30711679 Eur J Med Genet 2019 10.1016/j.ejmg.2019.01.016 0 0 0 50 Humans|Male|Child, Preschool|*Coloboma|*Heart Defects, Congenital|FGFR2 protein, human|Receptor, Fibroblast Growth Factor, Type 2|Phenotypes|Chromosome Deletion|Urogenital Abnormalities|*Chromosome Structures|Membrane Proteins|Growth Disorders|WDR11 protein, human|Proto-Oncogene Proteins 36 zic2 31884576 Cell Oncol (Dordr) 2019 10.1007/s13402-019-00485-5 0 0 0 286 *Nasopharyngeal Carcinoma|*RNA, Micro|*Lymphangiogenesis|Hedgehog Proteins|Neoplasm Invasiveness|Nasopharyngeal Neoplasms|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|*Lymphatic Metastasis|Cell Line, Tumor|Lymph Nodes 266 zic2 31847787 Open Biol 2019 PMC6936260 10.1098/rsob.190245 0 0 0 286 Animals|neuropeptide B|Neuropeptides|Ecdysis|Insect Hormones|Pupa|Drosophila melanogaster|Drosophila|Neurons|Gene Expression Regulation, Developmental|Larva|Signal Transduction 266 zic2 31813151 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 10.3760/cma.j.issn.1003-9406.2019.12.016 0 0 0 286 Child|Humans|*Chromosome Deletion|*Chromosome Disorders|*Genetic Testing|Abnormalities, Multiple|Karyotyping|Chromosome Banding|Mental Retardation|Phenotype|*Chromosome Structures 266 zic2 31782544 EMBO J. 2019 PMC6960450 10.15252/embj.2019102591 0 0 0 286 Mice|Animals|Mouse Embryonic Stem Cells|Epiblast|Transcription Factor|Pluripotent Stem Cells|Cell Differentiation|Gene Expression Regulation|Chromatin|Zfp281 protein, mouse 266 zic2 31681565 Front Oncol 2019 PMC6803498 10.3389/fonc.2019.01005 2 3 0 286 Humans|*Exosomes|*Melanoma|miRNAs|Gene Expression Regulation, Neoplastic|Cancer, Skin|Melanocytes|*Disease Progression|mRNA|Transcription Factors|Downregulation|Up-Regulation|Biomarkers|MIRN300 microRNA, human 266 zic2 31649488 Cancer Cell Int. 2019 PMC6805653 10.1186/s12935-019-0977-9 1 32 0 286 Humans|Male|Aged|*Epithelial-Mesenchymal Transition|*RNA, Micro|*Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|beta Catenin|Neoplasm Invasiveness|*Catenins|*Prostate Cancer|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Neovascularization, Pathologic|ZIC2 protein, human|Nuclear Proteins|Transcription Factors|Mirn129 microRNA, human 266 ADGRV1 30531642 Otol. Neurotol. 2018 10.1097/MAO.0000000000002054 6 0 0 90 Humans|*Usher Syndromes|DNA Mutational Analysis|Sequencing, Next-Generation|Pedigree|Genetic Association Studies|Mutation|Genotype|Nonsyndromic Deafness 27 ADGRV1 30459346 Sci Rep 2018 PMC6244211 10.1038/s41598-018-35085-0 5 0 0 90 Humans|Usher syndrome, type 2A|Usher Syndrome, Type IC|Usher Syndrome, Type IG|*Usher Syndromes|Comparative Genomic Hybridization|*High-Throughput Nucleotide Sequencing|DNA Mutational Analysis|Mutations|Pedigree|Nonsense Mutations|Phenotype|CLRN1 protein, human|Membrane Proteins|Cep250 protein, human|Autoantigens|Cell Cycle Proteins 27 ADGRV1 29961073 Cell. Physiol. Biochem. 2018 10.1159/000491068 3 0 0 90 Mice|Animals|*Usher Syndromes|*Mice, Inbred CBA|*Mutation|Electroretinography|*Disease Models, Animal|Retinal Degeneration|Retina|Phenotypes|Auditory Brain Stem Response|Mice, Inbred Strains|Genotypes 27 ADGRV1 29883260 Ophthalmic Genet. 2018 10.1080/13816810.2018.1479430 1 0 0 90 Humans|Usher syndrome, type 2C|*Usher Syndromes|*Chinese|Pedigree|Heterozygote|Mutation|Audiometry|Family 27 ADGRV1 29796015 Neural Plast. 2018 PMC5896214 10.1155/2018/2062346 1 19 0 90 27 ADGRV1 29777677 Exp. 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Commun. 2018 10.1016/j.bbrc.2018.12.100 0 1 0 67 Animals|Mice|BDNF protein, human|*Brain-Derived Neurotrophic Factor|*Neurotrophin 3|NTF3 protein, human|*Synapses|Hippocampus|*Brain|Cerebellum|Parietal Cortex|Cortex, Prefrontal|Neostriatum|Corpus Striatum|Neurogenesis|Gray Matter|Mice, Knockout 37 CADPS2 30302725 Mol. Neurobiol. 2018 PMC6505521 10.1007/s12035-018-1377-1 2 2 0 67 Mice|Animals|*Methylation|Histone H3|Histone-Lysine N-Methyltransferase|Lysine|*Cerebellum|Cell Differentiation|Protein Processing, Post-Translational|Cell Proliferation|Dot1l protein, mouse 37 CADPS2 29867227 Nat. Med. 2018 PMC6348479 10.1038/s41591-018-0040-8 93 0 0 67 Female|*Recognition, Psychology|Immunotherapy|Ovary|Melanoma|Bladder Cancer|Adoptive Transfer|Tobacco Smoking|Rates, Mutation|Smoking|Lung Cancers|Rare Diseases|Gastrointestinal Tract|Iodine 37 CADPS2 29689341 Neurosci. Lett. 2018 10.1016/j.neulet.2018.04.036 0 0 0 67 Mice|Animals|*Mossy Fibers, Hippocampal|*Calmodulin|*Synapse|Presynaptic Terminals|Postsynaptic Density|Synaptic Vesicles|Synaptic Transmission|Cryopyrin-Associated Periodic Syndromes|Hippocampus|Memory|Learning|Cytoplasmic Granules|Mice, Knockout|*Biological Phenomena|Organization|Organogenesis 37 CADPS2 29564645 J. Appl. Genet. 2018 10.1007/s13353-018-0440-y 0 0 0 67 Humans|*Autism Spectrum Disorder|DNA Copy Number Variations|*Karyotyping|Intellectual Disability|Neurodevelopmental Disorders|Genetic Testing|Genomics|Phenotype|Marital Status|Research Design|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins|NLGN4X protein, human|Cell Adhesion Molecules, Neuronal 37 CDKN2AIP 30374086 Nat. Struct. Mol. Biol. 2018 PMC6223542 10.1038/s41594-018-0143-4 10 5 0 154 Humans|*Cytosol|*RNA, Long Noncoding|*Mitochondria|RNA, Ribosomal|Protein, Mitochondrial|Cell Nucleus|RNA Processing, Post-Transcriptional|Ribosomes|RNA Precursors|Exoribonucleases|Protein Biosynthesis|RNA Binding Protein|Cell Nucleolus|HeLa Cells|HEK293 Cells|Oncogenes|XRN2 protein, human 19 CDKN2AIP 29748568 Oncogenesis 2018 PMC5945778 10.1038/s41389-018-0048-4 3 1 0 154 *Epithelial-Mesenchymal Transition|*Signal Transduction|Cell Proliferation|*Catenins|Apoptosis Regulatory Proteins|Gene Expression Regulation, Neoplastic|beta Catenin|Tumor Suppressor Protein p53|siRNA|Cell Line, Tumor|Transcription Factors|Upregulation|Apoptosis|Cell Transformation, Neoplastic 19 CEP120 29847808 Cell Rep 2018 PMC5990496 10.1016/j.celrep.2018.04.100 2 0 0 226 Centriole|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Jeune syndrome|Ellis-Van Creveld Syndrome|Eye Abnormalities|Ciliopathies|CNTRL protein, human|Cell Cycle Proteins|Abnormalities, Multiple|*Mutations|Cilia|Cerebellum|Phenotype|Retina 22 CEP120 29741480 Elife 2018 PMC5986273 10.7554/eLife.35439 4 15 0 226 Humans|Mice|Animals|*Centrioles|Centrosome|CNTRL protein, human|Cell Cycle Proteins|Microtubule-Associated Proteins|Dynein|Cilia|Jeune syndrome|Ellis-Van Creveld Syndrome|Carrier Proteins|Cell Cycle|*Cell Division|Cell Line|Protein Transport|CEP120 protein, human|Cdk5rap2 protein, mouse 22 CEP120 29458881 Taiwan J Obstet Gynecol 2018 10.1016/j.tjog.2017.12.021 3 0 0 226 Pregnancy|Female|Humans|Short rib-polydactyly syndrome, Verma-Naumoff type|*Short Rib-Polydactyly Syndrome|*Prenatal Diagnosis|*Mutations|Cytoplasmic Dyneins|*Polydactyly|Fetus|*Ribs|DYNC2H1 protein, human 22 CEP120 29398280 J. Struct. Biol. 2018 10.1016/j.jsb.2018.01.009 2 3 0 226 Humans|*Tubulin|*C2 Domains|Centrioles|Microtubules|*Protein Binding|Microtubule-Associated Proteins|Cell Cycle Proteins|Binding Sites|Amino Acid Sequence|Ciliopathies|Protein Domains|Models, Molecular|CEP120 protein, human 22 CERKL 30205735 Autophagy 2018 PMC6351130 10.1080/15548627.2018.1520548 4 3 0 65 *Sirtuin 1|*NAD|*Autophagy|Retinal Degeneration|Retina|ceramide kinase|Phosphotransferases (Alcohol Group Acceptor)|Retinitis Pigmentosa|Phosphorylation|RNA, Messenger|Downregulation 57 CERKL 29555955 Sci Rep 2018 PMC5859282 10.1038/s41598-018-22096-0 15 0 0 65 Humans|*Cone-Rod Dystrophies|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|Retinitis Pigmentosa|Electroretinography|DNA Mutational Analysis|Mutations|Sequencing, Next-Generation|Phenotype|Genotype-Phenotype Correlations|Retina|Eye Proteins|Pedigree|Macular Degeneration|Coherence Tomography, Optical|Visual Acuity|NPHP1 protein, human|Membrane Proteins 57 CERKL 29435412 FEBS Open Bio 2018 PMC5794457 10.1002/2211-5463.12360 15 2 0 65 miRNAs|Retinal Pigment Epithelium|Oxidative Stress|Retinitis Pigmentosa|Signal Transduction|*Neurons|Epithelial Cells|Retinal Pigments 57 CIB2 30531642 Otol. Neurotol. 2018 10.1097/MAO.0000000000002054 6 0 0 387 Humans|*Usher Syndromes|DNA Mutational Analysis|Sequencing, Next-Generation|Pedigree|Genetic Association Studies|Mutation|Genotype|Nonsyndromic Deafness 44 CIB2 30459346 Sci Rep 2018 PMC6244211 10.1038/s41598-018-35085-0 5 0 0 387 Humans|Usher syndrome, type 2A|Usher Syndrome, Type IC|Usher Syndrome, Type IG|*Usher Syndromes|Comparative Genomic Hybridization|*High-Throughput Nucleotide Sequencing|DNA Mutational Analysis|Mutations|Pedigree|Nonsense Mutations|Phenotype|CLRN1 protein, human|Membrane Proteins|Cep250 protein, human|Autoantigens|Cell Cycle Proteins 44 CIB2 30303587 Hum. Mutat. 2018 PMC6296877 10.1002/humu.23666 3 0 0 387 Humans|Pakistan|*Hearing Loss|Nonsyndromic Deafness|Deafness|Pedigree|Homozygote|Whole Exome Sequencing|Genes, Recessive|Genetic Testing|Genetic Predisposition to Disease|Mutation|Phenotype|*Ethnic Groups|Genetic Counseling 44 CIB2 30291150 Cold Spring Harb Perspect Med 2018 PMC6450785 10.1101/cshperspect.a033506 2 0 0 387 Humans|Mice|Animals|Mechanotransduction, Cellular|*Hair Cells, Auditory, Inner|Hair Cells, Auditory|Stereocilia|Membrane Proteins|Hearing|Mutation|Pcdh15 protein, mouse|Protein Precursors|Cadherins 44 CIB2 30174586 Front Mol Neurosci 2018 PMC6107761 10.3389/fnmol.2018.00274 3 2 0 387 Calcium-Binding Proteins|Calcium|Amino Acid Sequence|Pedigree|Protein Binding 44 CIB2 30055715 Int. J. Pediatr. Otorhinolaryngol. 2018 10.1016/j.ijporl.2018.06.012 2 0 0 387 Humans|Infant, Newborn|*Genetic Heterogeneity|Nonsyndromic Deafness|*Deafness|*Hearing Loss, Sensorineural|Connexin 26|Connexins|Gene Frequency|Hearing Loss|Mutation|Alleles|Genetic Predisposition to Disease|Algeria 44 CIB2 29658965 Genet. Mol. Biol. 2018 PMC5901489 10.1590/1678-4685-GMB-2016-0101 3 10 0 387 Swine|Animals|Poland|*Meat|*Breeding|*Transcriptome Analysis|*Skeletal Muscles|Muscle Development|*Phenotype|Sus scrofa|Transcriptome|Muscle Fibers, Skeletal|Lipid Metabolism 44 CPA1 30310075 Nat Commun 2018 PMC6181914 10.1038/s41467-018-06770-5 8 1 0 1982 *Antiporters|*Protons|*Phylogeny|*Cations|Binding Site|Amino Acid Sequence 143 CPA1 30045879 Gut 2018 PMC6326849 10.1136/gutjnl-2018-315994 8 1 0 1982 Humans|Carboxypeptidases A|Chronic Pancreatitis|Genetic Susceptibility|Chymotrypsin|Mutations|Trypsin|Endoplasmic Reticulum Stress 143 CPA1 30016235 Int. J. Syst. Evol. Microbiol. 2018 10.1099/ijsem.0.002899 0 0 0 1982 Saccharospirillum mangrovi|*Gammaproteobacteria|RNA, Ribosomal, 16S|Base Composition|DNA, Bacterial|Phylogeny|Bacterial Typing Techniques|Geologic Sediments|Sequence Analysis, DNA|Phospholipids|Fatty Acids|*Bacteria 143 DDRGK1 30228783 World J. Gastroenterol. 2018 PMC6141336 10.3748/wjg.v24.i34.3898 2 0 0 145 Humans|*Stomach Neoplasms|Gastrectomy|Adenocarcinoma|Neoplasm Staging|Kaplan-Meier Estimate|Biomarkers, Tumor|Lymphatic Metastasis|Nerve Tissue Proteins|CDK5RAP3 protein, human|Intracellular Signaling Peptides and Proteins 19 DDRGK1 29622492 Neurobiol. Aging 2018 10.1016/j.neurobiolaging.2018.03.005 2 0 0 145 Humans|*Parkinson Disease|Genome-Wide Association Study|*Asian|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|GTP Cyclohydrolase|Alleles|Genetic Loci|Genetic Variation|Case-Control Studies|Risk Factors|Odds Ratio|VPS13C protein, human|Proteins 19 DDRGK1 29533670 J. Proteome Res. 2018 10.1021/acs.jproteome.7b00843 2 1 0 145 Humans|Animals|*Proteomics|Percutaneous Coronary Intervention|*Ubiquitination|E3 Ligase|Protein Modification, Post Translational|Proteasome Endopeptidase Complex|Adaptor Proteins, Signal Transducing|HEK293 Cells|Downregulation|UFM1 protein, human|Proteins 19 DDRGK1 29321365 J. Genet. 2018 10.1007/s12041-017-0854-z 2 0 0 145 Humans|Genome-Wide Association Study|*Exome|Republic of Korea|*Myocardial Infarction|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Coronary Artery Disease|Asian Continental Ancestry Group|Genotype|Whole Exome Sequencing|*Genetic Testing|Risk Factors|DIS3L protein, human|Ribonucleases 19 ddx3y 30189373 Environ. Toxicol. Pharmacol. 2018 10.1016/j.etap.2018.08.012 0 0 0 71 Mice|Male|Animals|Humans|*Testosterone|*Arsenic|Sperm Motility|Sexual Maturation|*Spermatogenesis|Testis|Seminiferous Tubules|Sperm|Sperm Count|Androgen Binding Protein|Luteinizing Hormone|Receptor, Luteinizing Hormone|17-Hydroxysteroid Dehydrogenases|3-Hydroxysteroid Dehydrogenases|steroidogenic acute regulatory protein|Phosphoproteins|*Testosterone Congeners|Downregulation 104 ddx3y 29520635 Interdiscip Sci 2018 10.1007/s12539-018-0290-7 0 0 0 71 Male|Humans|*Polymorphism, Single Nucleotide|*Infertility, Male|Computational Biology|Binding Sites|In Silico|Protein Conformation|Software|Amino Acid Sequence|Models, Molecular|Mutation|Spermatogenesis 104 DISP1 30160831 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.38712 0 0 0 24 Child|Child, Preschool|Humans|Female|*Frameshift Mutation|*Drug Resistant Epilepsy|Deletions, Chromosome|Intellectual Disability|*Phenotype|Chromosome Disorders|Developmental Disabilities|Sequencing, Whole Exome|*Musculoskeletal Abnormalities|Nervous System Malformations|Syndrome|Mutation, Nonsense|Mutation|WDR26 protein, human|Proteins|Cohort Studies|FBXO28 protein, human|SKP Cullin F-Box Protein Ligases 34 DISP1 29953682 Hum Psychopharmacol 2018 10.1002/hup.2659 1 0 0 24 Humans|*Pharmacogenetics|Genome-Wide Association Study|*Obsessive Compulsive Disorder|*Antidepressive Agents|Serotonin Uptake Inhibitors|*Pharmacogenomic Testing|Fluvoxamine|Clomipramine|Fluoxetine|Treatment Outcome|Polymorphism, Genetic 34 DNAH11 32226575 Int J Clin Exp Pathol 2018 PMC7090253 0 0 0 12 Genetic Association Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Stroke|Genotype|Coronary Artery Disease|Risk Factors|Lipids 63 DNAH11 30471718 Am. J. Hum. Genet. 2018 PMC6288205 10.1016/j.ajhg.2018.10.020 8 1 0 12 Humans|DNAH9 protein, human|*Axonemal Dyneins|Axoneme|Kartagener Syndrome|Cilia|*Mutations|Phenotype|Pedigree 63 DNAH11 30359267 BMC Med Genomics 2018 PMC6202811 10.1186/s12920-018-0409-z 1 0 0 12 Pregnancy|Female|Humans|Child|*Whole Exome Sequencing|Prenatal Diagnosis|Fetuses|Ultrasonography, Prenatal 63 DNAI1 30471718 Am. J. Hum. Genet. 2018 PMC6288205 10.1016/j.ajhg.2018.10.020 8 1 0 22 Humans|DNAH9 protein, human|*Axonemal Dyneins|Axoneme|Kartagener Syndrome|Cilia|*Mutations|Phenotype|Pedigree 64 DNAI1 30300419 PLoS ONE 2018 PMC6177184 10.1371/journal.pone.0205422 4 1 0 22 Humans|Axonemal Dyneins|Kartagener Syndrome|Heterozygote|Mutation|Exome|Cilia|High-Throughput Nucleotide Sequencing|Genetic Testing|Homozygote|*Genetic Profile|Genomics|Cohort Studies 64 DNAI1 29635245 Int. Arch. Allergy Immunol. 2018 10.1159/000488014 3 0 0 22 *Down-Regulation|*Nasal Mucosa|Allergic Rhinitis|Th2 Cells|Immunoglobulin E|Cilia|RNA, Messenger 64 DNAI1 29601588 PLoS Genet. 2018 PMC5895051 10.1371/journal.pgen.1007316 9 2 0 22 Animals|Mice|Axoneme|Cilia|Kartagener Syndrome|*Cytoplasm|Axonemal Dyneins|Phenotypes|Pedigree|Tumor Suppressor Proteins|*Cytosol|Mutation|Lrrc6 protein, mouse|Proteins 64 DNAI1 29541990 Sci China Life Sci 2018 10.1007/s11427-017-9161-4 5 0 0 22 Animals|*Genome-Wide Association Study|*Genotype|Reproducibility of Results|*Bass|*Phenotype|Chromosome Mapping|DNA Sequencing|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Fish Proteins|Base Sequence|China 64 DNAI1 29429202 Zhonghua Er Ke Za Zhi 2018 10.3760/cma.j.issn.0578-1310.2018.02.012 0 0 0 22 64 DNAI2 30471718 Am. J. Hum. Genet. 2018 PMC6288205 10.1016/j.ajhg.2018.10.020 8 1 0 30 Humans|DNAH9 protein, human|*Axonemal Dyneins|Axoneme|Kartagener Syndrome|Cilia|*Mutations|Phenotype|Pedigree 30 DNAI2 30081822 Genet. Sel. Evol. 2018 PMC6080523 10.1186/s12711-018-0412-z 5 2 0 30 Swine|Animals|*Genome-Wide Association Study|*Semen|*Gene Regulatory Networks|Quantitative Trait Loci|*Phenotypes|Genotypes|Sus scrofa|Single Nucleotide Polymorphisms 30 DNAI2 29601588 PLoS Genet. 2018 PMC5895051 10.1371/journal.pgen.1007316 9 2 0 30 Animals|Mice|Axoneme|Cilia|Kartagener Syndrome|*Cytoplasm|Axonemal Dyneins|Phenotypes|Pedigree|Tumor Suppressor Proteins|*Cytosol|Mutation|Lrrc6 protein, mouse|Proteins 30 DNAI2 29386911 J Inflamm Res 2018 PMC5767096 10.2147/JIR.S149156 1 24 0 30 Humans|*Interleukin-13|histone H3 trimethyl Lys4|Epigenesis, Genetic|Nasal Polyps|Sinusitis|Rhinitis|*Histones|Nasal Mucosa|Cytokines|*Cell Differentiation|Cells, Epithelial|Cells, Cultured|RNA, Messenger 30 DRC1 30243945 Immunol. Lett. 2018 10.1016/j.imlet.2018.09.003 1 0 0 38 Mice|Animals|*Immunologic Memory|T-Lymphocytopenia|*Lymphopenia|CD8-Positive T-Lymphocytes|T-Cell Subset|Cell Differentiation|*Homeostasis|Cell Proliferation|Antigens|Cytokines|Mice, Inbred C57BL 45 DRC1 29529077 PLoS ONE 2018 PMC5847310 10.1371/journal.pone.0194293 0 5 0 38 Animals|Male|Rats|*Quantitative Trait Loci|*Wistar Kyoto Rats|*Rats, Inbred F344|Chromosome Mapping|Animals, Congenic|Phenotype|Gene Expression Profiling|*Brain|Microarray Analysis 45 DRC1 29467202 Eur. Respir. J. 2018 10.1183/13993003.01809-2017 7 0 0 38 Humans|Axonemal Dyneins|Kartagener Syndrome|Cilia|Phenotype|*Tomography, X-Ray Computed|Mutation|Transmission Electron Microscopy|DNAH11 protein, human 45 FAM111A 30333173 J. Virol. 2018 PMC6288344 10.1128/JVI.01330-18 1 1 0 19 *Simian virus 40|*Host Specificity|DNA, Viral|Virus Replication|Large T-Antigen|Antigens, Polyomavirus Transforming|DNA Replication|Genes, Viral|Viral Proteins|Cell Line|*Phenotype|Mutations|Gene Expression|Cell Cycle|Cell Cycle Proteins 19 FAT2 29847346 Curr. Opin. Neurol. 2018 10.1097/WCO.0000000000000585 10 0 0 52 *Ataxias, Hereditary|Spastic Paraplegias, Hereditary|Spastic Ataxia|Spinocerebellar Ataxias|Optic Atrophy|Phenotype|Muscle Spasticity|Intellectual Disability|Mutation 58 FAT2 29420170 Elife 2018 PMC5805408 10.7554/eLife.32943 9 4 0 52 Animals|STAT Transcription Factors|Janus Kinases|Drosophila Proteins|Drosophila|Drosophila melanogaster|Oogenesis|Cell Polarity|Transcription Factors|Signal Transduction|Morphogenesis|Gene Expression Regulation, Developmental|Epithelial Cells 58 FAT2 29371917 Oncotarget 2018 PMC5768334 10.18632/oncotarget.23009 6 0 0 52 Humans|*Lung Cancers|Immunohistochemistry|Adenocarcinoma|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|LYPD3 protein, human|Cell Adhesion Molecules|GPI-Linked Proteins|Kaplan-Meier Analysis|Gene Expression|Lung|FAT2 protein, human|Cadherins|GPR87 protein, human|Receptors, Lysophosphatidic Acid|TMPRSS4 protein, human|Membrane Proteins 58 FKTN 30233323 Front Cell Neurosci 2018 PMC6133952 10.3389/fncel.2018.00284 3 0 0 124 Female|Pregnancy|Humans|*GABAergic Neurons|Parvalbumins|Interneurons|Synaptic Transmission|Glutamate Decarboxylase|*Extracellular Matrix|gamma-Aminobutyric Acid|Prefrontal Cortex 146 FKTN 30220444 Neuromuscul. Disord. 2018 10.1016/j.nmd.2018.08.001 1 0 0 124 Male|Humans|Female|*Walker-Warburg Syndrome|Japan|Retrospective Studies|Dystrophy, Muscular|Mutation|Membrane Proteins|*Registry 146 FKTN 30060766 Skelet Muscle 2018 PMC6066920 10.1186/s13395-018-0170-1 6 3 0 124 Humans|*Muscle Weakness|*Whole Exome Sequencing|Muscular Dystrophies, Limb-Girdle|Dystroglycan|Mutations|Phenotype|Muscle, Skeletal|Nucleotidyltransferases|*Cohort Studies|Mutation, Missense|Glycosylation 146 FKTN 29884773 J. Biol. Chem. 2018 PMC6078450 10.1074/jbc.RA118.003197 3 3 0 124 Humans|*Glycerol|Dystroglycan|Muscular Dystrophies|Glycosylation|Pentosyltransferases|Laminin|HEK293 Cells|Cytidine Diphosphate 146 FKTN 29477842 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.02.162 2 4 0 124 *Ribitol|UDP xylose-protein xylosyltransferase|Dystroglycan|*Pentosyltransferases|Muscular Dystrophies|Glycosylation|Transferases|Glycans 146 FKTN 29416295 Mol. Vis. 2018 PMC5783743 0 6 0 124 Animals|Dystroglycan|Walker-Warburg Syndrome|ribitol-5-phosphate|Pentosephosphates|Glycosylation|Protein Processing, Post-Translational|Muscle, Skeletal|Transferases|*Retinal Neurons 146 FKTN 29327352 Prenat. Diagn. 2018 10.1002/pd.5201 2 0 0 124 Humans|Pregnancy|Female|*Homozygote|Prenatal Diagnosis|Single Nucleotide Polymorphism|Pedigree|Ethnic Groups|Microarray Analysis|Mutation 146 frem1 29855589 Sci Rep 2018 PMC5981322 10.1038/s41598-018-26880-w 0 1 0 54 Cleft Lip|*Genome-Wide Association Study|Velopharyngeal Insufficiency|Cleft Palate|Palate, Soft|Pharynx|Speech 58 frem1 29688405 Hum. Mol. Genet. 2018 PMC6251612 10.1093/hmg/ddy144 3 2 0 54 Humans|Fraser Syndrome|*Homozygote|Marles Greenberg Persaud syndrome|Hypertelorism|Coloboma|*Mutation|Abnormalities, Multiple|*Microphthalmos|Renal Adysplasia|Urogenital Abnormalities|Phenotype|Pedigree|Extracellular Matrix Proteins|Frameshift Mutation|Receptors, Interleukin|Anal Canal|Mutations, Missense|Hereditary renal agenesis 58 frem1 29618029 Hum. Mol. Genet. 2018 PMC5985720 10.1093/hmg/ddy110 2 4 0 54 Humans|Female|Pregnancy|Mice|Animals|Hernia, Anterior Diaphragmatic|*Hernias, Diaphragmatic, Congenital|Fraser Syndrome|Diaphragm|Extracellular Matrix Proteins|Mutations|Extracellular Matrix|FRAS1 protein, human|FREM2 protein, human|Fras1 protein, mouse 58 FRMD7 30576400 Acta Biochim. Biophys. Sin. (Shanghai) 2018 10.1093/abbs/gmy161 0 1 0 40 Male|Humans|Child|X-Linked Infantile Nystagmus|*Nystagmus, Congenital|*Mutation, Missense|Genetic Diseases, X-Linked|X-Linked Inheritance|Cytoskeletal Proteins|Pedigree|Membrane Proteins|Mutation|Chinese|*Nystagmus, Pathologic|Phenotype|FRMD7 protein, human 79 FRMD7 30025138 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24207 2 0 0 40 *Nystagmus, Pathologic|Nystagmus, Congenital|*Phenotype|Cytoskeletal Proteins|*Genotype|Genetic Diseases, X-Linked|DNA Mutational Analysis|Membrane Proteins|Pedigree|Mutation|Mutation, Missense 79 FRMD7 30015830 Mol Med Rep 2018 PMC6102629 10.3892/mmr.2018.9260 0 0 0 40 Male|Humans|radixin|ezrin|*Mutation, Missense|*Cytoskeletal Proteins|*Membrane Proteins|Congenital Nystagmus|Pedigree|Genetic Diseases, X-Linked|DNA Mutational Analysis|Mutations|Phenotype|Genes, X-Linked|Chinese|Exon|Base Sequence|FRMD7 protein, human 79 FSCN2 30082328 G3 (Bethesda) 2018 PMC6169377 10.1534/g3.118.200405 2 3 0 24 Humans|*Loss of Function Mutation|Stereocilia|Microfilament Proteins|Hearing Loss|Alleles|Carrier Proteins|Actin 34 FSCN2 29744916 J. Cell. Biochem. 2018 10.1002/jcb.26871 1 0 0 24 Humans|Retinitis Pigmentosa|*Retina|Eye Proteins|RNA Splicing|Genes, Dominant|Photoreceptor Cells|*Retinitis|mRNA|Mutation|Gene Expression Regulation|Cell Line|Transcription Factor|Gene Expression|Western Blot|PRPF31 protein, human 34 FUCA1 30157205 PLoS ONE 2018 PMC6114296 10.1371/journal.pone.0202017 1 0 0 69 Cattle|Animals|Female|Humans|Ovarian Follicle|*Oviducts|Breeding|Ovulation|*Gene Expression 69 FUCA1 29706874 Front Behav Neurosci 2018 PMC5906539 10.3389/fnbeh.2018.00069 0 0 0 69 Humans|Animals|Mice|*Fucosidosis|*Neuropathology|alpha-L-Fucosidase|*Impairments, Cognitive|Lysosomal Storage Diseases|Brain|*Telencephalon|Disease Models, Animal|Phenotype|*Nervous System Diseases|Lysosomes|Purkinje Cells 69 FUCA1 29588375 J. Clin. Pathol. 2018 10.1136/jclinpath-2018-205074 0 0 0 69 *Frameshift Mutation|Fucosidosis|*Homozygote|alpha-L-Fucosidase|Base Sequence|Exons|Mutation|Pedigree|Lysosomal Storage Diseases|Polymerase Chain Reaction 69 FUCA1 29518279 Exp. Dermatol. 2018 10.1111/exd.13532 3 0 0 69 Humans|*Fucosidosis|*Fucosidase|*Keratinocytes|*Transcriptome|Lysosomal Storage Disease|Angiokeratoma Corporis Diffusum|Mutation|*Skin Diseases|Phenotype|*Transcriptome Analysis|FUCA1 protein, human 69 GNPTG 30507725 Clin. Dysmorphol. 2018 10.1097/MCD.0000000000000249 1 0 0 56 Humans|*Mucolipidoses|*Phenotype|Transferases (Other Substituted Phosphate Groups)|Genotype|Mutations|Homozygote|*Cohort Studies|India|Turkey|GNPTG protein, human 50 GNPTG 30235039 Genet Test Mol Biomarkers 2018 10.1089/gtmb.2018.0123 0 1 0 56 Mucolipidosis III Gamma|Pakistan|*Mucolipidoses|*Sequencing, Next-Generation|Transferases (Other Substituted Phosphate Groups)|*Genetic Testing|Mutations|Mutation, Missense|*Family 50 GNPTG 29872134 Acta Pharmacol. Sin. 2018 PMC6329779 10.1038/s41401-018-0023-9 3 0 0 56 Humans|Female|Pregnancy|*Mucolipidoses|Transferases (Other Substituted Phosphate Groups)|*Mutations|Exon|*Prenatal Diagnosis|Heterozygote|Phenotype|mannose-6-phosphate|Mannosephosphates|Genetic Testing|Lysosomes|China|GNPTG protein, human|GNPTAB protein, human 50 GNPTG 29773673 Mol. Cell Proteomics 2018 PMC6072544 10.1074/mcp.RA118.000720 4 0 0 56 Mice|Animals|*Mucolipidoses|*Proteome|mannose-6-phosphate|Mannosephosphates|*Lysosomes|Transferases (Other Substituted Phosphate Groups)|Hydrolases|Phenotype|Phosphotransferases|Mutation 50 GNPTG 29346494 Invest. Ophthalmol. Vis. Sci. 2018 PMC5773233 10.1167/iovs.17-22173 12 0 0 56 *Syndromes|*Myopia|Refractive Errors|Hyperopia|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Eye Proteins 50 GNPTG 29289611 Gene 2018 10.1016/j.gene.2017.12.054 2 0 0 56 *Stuttering|Iran|Mucolipidosis|Transferases (Other Substituted Phosphate Groups)|Homozygote|Mutations|Phenotype|Heterozygote|Phosphoric Diester Hydrolases|Introns 50 GSDMC 30261039 PLoS Genet. 2018 PMC6159857 10.1371/journal.pgen.1007601 14 4 0 11 Humans|Adult|Genome-Wide Association Study|Locus, Genetic|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Cohort Studies|Case-Control Studies|Logistic Models|Genomics|Aging|*Back Pain 19 GSDMC 30226565 Int. J. Mol. Med. 2018 10.3892/ijmm.2018.3839 0 2 0 11 Humans|*Calcineurin|*Calcium|*Ultraviolet Rays|*Nuclear Factor-1|*Calcium Signaling|MMP1 protein, human|Metalloproteinase 1, Matrix|Keratinocytes|Skin|TRPV Cation Channels|*Calcium, Dietary|capsazepine|Capsaicine|*Cytoplasm|Ruthenium Red|*Cytosol|Cell Line|*Biochemical Phenomena 19 GSDMC 29990470 J. Mol. Biol. 2018 10.1016/j.jmb.2018.07.002 28 0 0 11 Humans|Mice|Animals|*Inflammasomes|Pyroptosis|CASP5 protein, human|Caspases|Casp1 protein, mouse|Caspase 1|CASP4 protein, human|Caspases, Initiator|Neoplasm Proteins|*Cell Death|*Signal Transduction|Cell Membrane|GSDMA protein, human|GSDMD protein, human|pejvakin protein, mouse|Proteins 19 GSDMC 29428815 J. Dermatol. Sci. 2018 10.1016/j.jdermsci.2018.01.015 1 6 0 11 MMP1 protein, human|*Matrix Metalloproteinase 1|*Ultraviolet Rays|*MAP Kinase Signaling System|Skin|Keratinocytes|Skin Aging|Fibroblasts|Cells, Cultured|Cell Line|Signal Transduction 19 HEPACAM 30528714 Urology 2018 10.1016/j.urology.2018.11.033 0 1 0 129 *Carcinoma, Renal Cell|Kidney Neoplasms|*Signal Transduction|Von Hippel-Lindau Tumor Suppressor Protein|Transcription Factors|Gene Expression Regulation, Neoplastic|Vascular Endothelial Growth Factor A|RNA, Messenger|Cell Proliferation 70 HEPACAM 30076890 Neurobiol. Dis. 2018 10.1016/j.nbd.2018.07.031 4 8 0 129 Humans|Megalencephalic leukoencephalopathy with subcortical cysts|*Hereditary Central Nervous System Demyelinating Diseases|*Cysts|*Megalencephaly|Membrane Proteins|ClC-2 chloride channels|Chloride Channels|Astrocytes|Cell Cycle Proteins|Mutations|Protein Transport|Brain|HEK293 Cells|*Nervous System Malformations|*Anions|Chlorides|MLC1 protein, human|LRRC8A protein, human 70 HEPACAM 29973580 Med. Sci. Monit. 2018 PMC6065283 10.12659/MSM.907224 7 8 0 129 Humans|*Prognosis|*Colorectal Cancer|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Gene Expression Profiling|Databases, Genetic|Gene Expression Regulation, Neoplastic|Computational Biology|Biomarkers, Tumor|Transcriptome|*Colonic Neoplasms|Kaplan-Meier Analysis|MMP1 protein, human|Matrix Metalloproteinase 1 70 HEPACAM 29661901 Neurology 2018 PMC5902784 10.1212/WNL.0000000000005334 6 5 0 129 Megalencephalic leukoencephalopathy with subcortical cysts|Hereditary Central Nervous System Demyelinating Diseases|*Cysts|*Megalencephaly|Membrane Proteins|Cell Cycle Proteins|Magnetic Resonance Imaging|Mutation|Brain|*Nervous System Malformations 70 HEPACAM 29658567 Int. J. Oncol. 2018 PMC5958706 10.3892/ijo.2018.4370 8 41 0 129 Humans|Male|MDV 3100|*Docetaxel|nirogacestat|*Prostatic Neoplasms, Castration-Resistant|*Amyloid Precursor Protein Secretases|*Downregulation|*Phenylthiohydantoin|*Tetrahydronaphthalenes|*Valine|*Prostate|*Signal Transduction|Receptors, Androgen|Taxoids|Xenograft Model Antitumor Assays|Cell Line, Tumor|Drug Resistance, Neoplasm|Cell Proliferation|Apoptosis 70 HPS3 30557883 J Innate Immun 2018 PMC6738263 10.1159/000494147 1 1 0 43 Humans|Mice|Animals|*Pneumonia, Bacterial|Klebsiella Infections|*Sepsis|Klebsiella pneumoniae|*Thrombocytopenia|*Bacteremia|*Gram-Negative Bacterial Infections|Platelets|Lungs|Platelet Counts|Lung Diseases|Mice, Inbred C57BL|Immunity, Innate|Hemorrhage|Cytokines 51 HPS3 30387913 Pigment Cell Melanoma Res 2018 10.1111/pcmr.12748 0 0 0 43 Humans|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|*Hermanski-Pudlak Syndrome|Dilution, Pigmentary|Carrier Proteins|Membrane Proteins|Mutation|*Chinese|Intracellular Signaling Peptides and Proteins|Hypopigmentation|Sequencing, Next-Generation|Lysosome|Organelles|HPS3 protein, human 51 HPS3 30138987 Zhonghua Yi Xue Za Zhi 2018 10.3760/cma.j.issn.0376-2491.2018.30.010 0 0 0 43 51 HPS6 30387913 Pigment Cell Melanoma Res 2018 10.1111/pcmr.12748 0 0 0 1552 Humans|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|*Hermanski-Pudlak Syndrome|Dilution, Pigmentary|Carrier Proteins|Membrane Proteins|Mutation|*Chinese|Intracellular Signaling Peptides and Proteins|Hypopigmentation|Sequencing, Next-Generation|Lysosome|Organelles|HPS3 protein, human 44 HPS6 30369044 Am. J. Med. Genet. A 2018 PMC6312461 10.1002/ajmg.a.40514 0 0 0 1552 Adult|Humans|Female|Hermanski-Pudlak Syndrome|Sequencing, Next-Generation|Platelet Storage Pool Deficiency|Pedigree|Phenotype|*Mutation, Missense|Hypopigmentation|Mutation|Platelet|Intracellular Signaling Peptides and Proteins|*Bleeding|HPS6 protein, human 44 hydin 30535028 J Mol Cell Biol 2018 10.1093/jmcb/mjy014 8 1 0 24 Animals|Mice|*Microtubules|calponin|*Microfilament Proteins|Axoneme|Cilia|Microtubule-Associated Proteins|Ependyma|TYRP1 protein, human|*Membrane Glycoproteins|Calcium-Binding Proteins|Cell Movement|Chromosome Segregation|Protein Binding|*Mammals|Amino Acid Sequence|Transductions, Signal|SPAG6 protein, mouse|Microtubule Proteins 49 hydin 30155272 NPJ Genom Med 2018 PMC6105585 10.1038/s41525-018-0059-2 0 0 0 24 Humans|Male|Adult|Child|*DNA Copy Number Variations|Macrocephaly|Phenotype|Intellectual Disability|Autism|*Chromosome Structures|HYDIN protein, human|Microfilament Proteins 49 hydin 30089752 Exp. Anim. 2018 PMC6389518 10.1538/expanim.18-0071 3 0 0 24 Mice|Animals|Male|Humans|Sperm Motility|*Spermiogenesis|Spermatozoa|Acrosome|Acrosome Reaction|Mice, Transgenic|*Chimera|*Embryonic Stem Cells|Testis|Oocytes|Green Fluorescent Proteins|HYDIN protein, human|Microfilament Proteins 49 hydin 29505555 Med. Sci. Monit. 2018 PMC5849354 10.12659/msm.908923 0 0 0 24 Humans|Male|Female|*Whole Exome Sequencing|*Atrial Septal Defect|*Chinese|Exome|Mutations|Pedigree|Myosin Heavy Chains|Genetic Predisposition to Disease|Phenotype|Exon|Mutation Frequencies|Amino Acid Sequence 49 hydin 29467202 Eur. Respir. J. 2018 10.1183/13993003.01809-2017 7 0 0 24 Humans|Axonemal Dyneins|Kartagener Syndrome|Cilia|Phenotype|*Tomography, X-Ray Computed|Mutation|Transmission Electron Microscopy|DNAH11 protein, human 49 hydin 29429202 Zhonghua Er Ke Za Zhi 2018 10.3760/cma.j.issn.0578-1310.2018.02.012 0 0 0 24 49 hydin 29363216 Hum. Mutat. 2018 10.1002/humu.23403 3 0 0 24 Humans|Kartagener Syndrome|Exome|Axonemal Dyneins|Mutations|Sequence Analysis, DNA|Cohort Studies|DNAJB13 protein, human|Heat-Shock Proteins 49 IFNE 30329018 Biol. Reprod. 2018 PMC6437260 10.1093/biolre/ioy226 3 0 0 58 Pregnancy|Male|Humans|Cattle|Animals|Female|Swine|*Semen|*Endometrium|Artificial Insemination|Sperm|Uterus|Insemination|CXCL8 protein, human|Interleukin-8|Epithelial Cell|Embryo, Mammalian|TGFB1 protein, human|Transforming Growth Factor beta1|Cytokines|Stromal Cells|Cervix|PTGS2 19 IFNE 29905034 Am. J. Reprod. Immunol. 2018 10.1111/aji.12995 0 0 0 58 Animals|Female|Pregnancy|Humans|*Herpes Genitalis|*Pilot Projects|Herpesvirus 2, Human|Herpes Simplex|Sexually Transmitted Infections|Pregnancy Complications, Infectious|Herpesvirus 1, Human|*Reproduction|Virus Shedding|Antibodies, Viral|Vagina|Interferons 19 IFNE 29807828 Anim. Reprod. Sci. 2018 10.1016/j.anireprosci.2018.05.003 1 1 0 58 Pregnancy|Humans|Horses|Animals|Female|Mice|*Luteal Phase|*Endometrium|Estrous Cycle|Progesterone|Diestrus|Estradiol|Endometritis|*Up-Regulation|*Transcriptional Activation|Estrogens|RNA, Messenger|Glandular Epithelial Cells|Interferons 19 IFNK 30458775 BMC Syst Biol 2018 PMC6245593 10.1186/s12918-018-0612-8 0 0 0 71 Humans|*Linear Models|Sequence Analysis, RNA|Gene Expression Profiling|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Algorithms 19 IFNK 30037133 Pharmaceuticals (Basel) 2018 PMC6161188 10.3390/ph11030073 1 1 0 71 Mice|Animals|*Influenza A Virus, H1N1 Subtype|*Oligoribonucleotides|*Mannitol|*Innate Immune Response|Toll-Like Receptors|Influenza|Orthomyxoviridae Infections|Toll-Like Receptor 8|Toll-Like Receptor 7|Cytokines|Influenza A virus|NF-kappa B|Antiviral Agents 19 IFNK 30021804 Ann. Rheum. Dis. 2018 PMC6185784 10.1136/annrheumdis-2018-213197 19 2 0 71 Humans|interferon kappa|*Skin|*Type I Interferon|Cutaneous Lupus Erythematosus|*Photosensitivity Disorders|Keratinocytes|Ultraviolet Rays|Cells, Cultured|Apoptosis 19 IGHMBP2 30413626 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6275523 10.1073/pnas.1812135115 3 0 0 49 Humans|Animals|*Rainforest|*Multifactorial Inheritance|*Asian|*Adaptation, Physiological|Genetics, Population|Selection, Genetic|Phenotype|Gene Flow|Biological Evolution|African Continental Ancestry Group|*Acclimatization|Genetic Variation|Hominidae|Biological Adaptation|Body Size|Genomes|*Biological Phenomena|*Heart 118 IGHMBP2 30409445 Neuromuscul. Disord. 2018 10.1016/j.nmd.2018.09.008 0 1 0 49 Male|Humans|Infant, Newborn|Infant|*Charcot-Marie-Tooth Disease|DNA-Binding Proteins|Transcription Factors|Spinal muscular atrophy with respiratory distress 1|Muscular Atrophy, Spinal|Phenotype|Mutations|Pedigree|Respiratory Distress Syndrome, Newborn|*Muscle Weakness|IGHMBP2 protein, human 118 IGHMBP2 30385095 Neuromuscul. Disord. 2018 PMC6302219 10.1016/j.nmd.2018.08.010 2 0 0 49 Infant, Newborn|Humans|Female|Child|Adult|Spinal muscular atrophy with respiratory distress 1|Muscular Atrophy, Spinal|DNA-Binding Proteins|Transcription Factors|*Mutation|Respiratory Distress Syndrome, Newborn|Homozygote|Phenotypes|*Primary Dysautonomias|IGHMBP2 protein, human 118 IGHMBP2 30218034 Nat Commun 2018 PMC6138625 10.1038/s41467-018-06313-y 5 2 0 49 Humans|Decay, Nonsense-Mediated mRNA|RNA Helicases|*DNA Helicases|Trans-Activators|RNA, Messenger|DNA|HEK293 Cells|UPF1 protein, human|IGHMBP2 protein, human|DNA-Binding Proteins|Transcription Factors 118 IGHMBP2 30202772 Mol Ther Methods Clin Dev 2018 PMC6127875 10.1016/j.omtm.2018.08.005 3 0 0 49 Mice|Humans|Infant, Newborn|Animals|Spinal muscular atrophy with respiratory distress 1|*Muscular Atrophy, Spinal|*Respiratory Distress Syndrome, Newborn|DNA-Binding Proteins|Transcription Factors|*Disease Models, Animal|*Genetic Therapy|Motor Neurons|Muscle, Skeletal|Mutation 118 IGHMBP2 29928949 Neuroscience 2018 10.1016/j.neuroscience.2018.06.019 0 2 0 49 Humans|Infant, Newborn|Animals|Child|Spinal muscular atrophy with respiratory distress 1|*Actins|*mRNA|*Muscular Atrophy, Spinal|*Respiratory Distress Syndrome, Newborn|*Motoneuron|DNA-Binding Proteins|Transcription Factors|Mutations|immunoglobulin-binding factors|*Lymphokines|Phenotype|Base Sequence|Axons|Growth Cone|Disease Models, Animal|IGHMBP2 protein, human 118 IGHMBP2 29916023 Adv Neurobiol 2018 10.1007/978-3-319-89689-2_10 3 0 0 49 Animals|*RNA|*Transcriptome|*Neurobiology|SETX protein, human|*RNA Helicases|*Motor Neuron Disease|*DNA Helicase A|Amyotrophic lateral sclerosis 1|Amyotrophic Lateral Sclerosis|Apraxia, oculomotor, Cogan type|Cogan Syndrome|*Cerebellar Diseases|Ataxia|*Neurodegenerative Diseases|Motor Neuron|Transcription, Genetic|Cerebellar Ataxia|Mutations 118 IGHMBP2 29761130 Child Neurol Open 2018 PMC5946598 10.1177/2329048X18769811 0 0 0 49 Infant, Newborn|Humans|Child|Female|Spinal muscular atrophy with respiratory distress 1|*Muscular Atrophy, Spinal|Respiratory Distress Syndrome, Newborn|DNA-Binding Proteins|Transcription Factors|Spinal Muscular Atrophies of Childhood|Mutation|Paralysis, Diaphragmatic|Respiration Disorders|Muscle Weakness|*Dyspnea 118 IGHMBP2 29653221 Eur J Med Genet 2018 10.1016/j.ejmg.2018.04.001 0 1 0 49 Infant, Newborn|Humans|Male|Spinal muscular atrophy with respiratory distress 1|Muscular Atrophy, Spinal|Respiratory Distress Syndrome, Newborn|*Infantile Spinal Muscular Atrophy|DNA-Binding Proteins|Transcription Factors|*Phenotype|Mutation|Paralysis, Diaphragmatic|Muscle Hypertonia|Respiration Disorders|*Dyspnea|Muscle Weakness|IGHMBP2 protein, human 118 IGSF9 30217166 J Neuroinflammation 2018 PMC6138928 10.1186/s12974-018-1307-1 4 0 0 96 Humans|*Multiple Sclerosis|*Exome|*Whole Exome Sequencing|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|*Disease Progression|Genotype 19 IGSF9 29666643 J Oncol 2018 PMC5832105 10.1155/2018/2439527 0 0 0 96 Humans|Female|*RNA-Seq|*Endometrial Cancer|Carcinoma, Endometrioid|Endometrium|*Whole Exome Sequencing 19 IGSF9 29500156 Oral Surg Oral Med Oral Pathol Oral Radiol 2018 10.1016/j.oooo.2018.01.007 1 0 0 96 Humans|*Cleft Lip|*Cleft Palate, Isolated|Tooth Abnormalities|Genotype|Polymorphism, Single Nucleotide|*Syndrome|*Palate 19 IGSF9 29291926 J. Neurosci. Methods 2018 10.1016/j.jneumeth.2017.12.024 1 0 0 96 Mice|Animals|*Olivary Nucleus|*Transgenic Mouse|Purkinje Neurons|Neurons|Cerebellar Nuclei|Cerebellum|Synapses|Cerebellar Cortex|Action Potentials|Neural Pathways 19 IMPG2 30300315 Retin Cases Brief Rep 2018 10.1097/ICB.0000000000000824 0 1 0 17 Adult|Humans|*Vitelliform Macular Dystrophy|Bestrophins|Eye Proteins|Visual Acuity|Pedigree|Phenotype|Tomography, Optical Coherence|Mutation 26 IMPG2 29777959 Acta Biomater 2018 10.1016/j.actbio.2018.05.023 5 0 0 17 Humans|Mice|Animals|*Organoids|*Photoreceptor Cells|*Retina|*Pluripotent Stem Cell|*Extracellular Matrix|Photoreceptor Cells, Vertebrate|*Cell Differentiation|Proteoglycans|Eye Proteins|*Organogenesis|BCAN protein, human|Brevican|CD44 protein, human|Hyaluronan Receptors 26 IRX2 30112844 Mol. Ecol. 2018 10.1111/mec.14837 1 0 0 141 Animals|*Transcriptome|*Helping Behavior|Fish, Cichlid|Breeding|Behavior, Animal|Cooperative Behavior|*Brain|Reproduction|Phenotypes 71 IRX2 30108103 Clin. Cancer Res. 2018 PMC6295225 10.1158/1078-0432.CCR-18-1199 11 0 0 141 Humans|Female|*Ovarian Cancers|Cystadenocarcinoma, Serous|Fallopian Tube Neoplasms|DNA Methylation|Biomarkers, Tumor 71 IRX2 31949798 Int J Clin Exp Pathol 2018 PMC6962795 0 0 0 141 *Up-Regulation|Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Carcinoma|Prognosis 71 IRX2 30050001 Genes (Basel) 2018 PMC6115814 10.3390/genes9080374 3 14 0 141 *Diabetes Mellitus, Type 2|Genome-Wide Association Study|Transcription Factor 7-Like 2 Protein|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Genomics 71 jph2 30582449 Circ. Res. 2018 PMC6336523 10.1161/CIRCRESAHA.118.313811 1 0 0 218 Mice|Animals|*Atrial Fibrillation|Adeno-Associated Virus|*Gene Therapy|*Gene Transfer Techniques|Genetic Vectors|Cardiomyocytes|*Heart Atria|Promoter Regions, Genetic|Gene Expression|Troponin T|Cardiac Diseases 52 jph2 30566039 Circ. Res. 2018 10.1161/CIRCRESAHA.118.313916 5 3 0 218 *Sarcoplasmic Reticulum|*Calcium|Sarcoplasmic Reticulum Calcium-Transporting ATPases|Myocytes, Cardiac|*Calcium, Dietary|Calcium-Binding Proteins|*Biological Transport|Heart Failure 52 jph2 30384889 J. Am. Coll. Cardiol. 2018 10.1016/j.jacc.2018.08.2171 8 0 0 218 Child|Humans|Cardiomyopathies|Pedigree|Mutation|Mutation, Missense|Genetic Predisposition to Disease|Heart Failure 52 jph2 30235249 PLoS ONE 2018 PMC6147424 10.1371/journal.pone.0203422 4 1 0 218 Humans|*Heterozygote|junctophilin|*Cardiomyopathy, Hypertrophic|Cardiomyopathy, Hypertrophic, Familial|*Membrane Proteins|Cardiac Myosins|Pedigree|Mutations|Phenotype|Mutation, Missense|Sequencing, Next-Generation|Penetrance|*Heart Failure|Hypertrophy, Left Ventricular|Finland 52 jph2 29930145 Circ. Res. 2018 10.1161/CIRCRESAHA.118.313036 2 1 0 218 *Atrial Remodeling|*Transcription Factor|Heart Atria|Atrial Fibrillation|*Gene Expression Regulation|Myocytes, Cardiac|Fibrosis|Signal Transduction 52 jph2 29473235 Exp. Physiol. 2018 PMC6099270 10.1113/EP086731 6 0 0 218 *Caveolin 3|Calcium Signaling|Calcium Channels, L-Type|Myocytes, Cardiac|Heart Failure|*Caveolin 1|Heart Ventricles 52 KCNJ13 30561082 J. Neuroendocrinol. 2018 PMC6533113 10.1111/jne.12670 1 1 0 30 Humans|Mice|Animals|Rats|MC4R protein, human|*Receptor, Melanocortin, Type 4|*Potassium|Hyperphagia|Eating|Hypothalamus|Neurons|Energy Metabolism 40 KCNJ13 30257863 J. Biol. Chem. 2018 PMC6240878 10.1074/jbc.RA118.003238 1 2 0 30 Humans|Kir7.1 channel|*Potassium|*Glycosylation|HEK293 Cells|*Potassium Channels, Inwardly Rectifying|Leber Congenital Amaurosis|Retinal Degeneration|*G-Protein-Coupled Receptors|Retinal Pigment Epithelium|MC4R protein, human|Melanocortin 4 Receptor|Mutation|Amino Acid Sequence|Membrane Potential|Cell Membrane 40 KCNJ13 30252177 Mol. Ecol. 2018 10.1111/mec.14878 2 0 0 30 Animals|pheomelanin|Melanins|Pigmentation|Feathers|eumelanin|*Gene Expression Regulation|Biological Evolution|Songbirds|Genetic Variation|Oregon 40 KCNJ13 30228185 J. Biol. Chem. 2018 PMC6231133 10.1074/jbc.RA118.005484 8 1 0 30 Humans|Mice|Animals|*Retinal Cone Photoreceptor Cells|*Retinal Pigment Epithelium|Retinal Rod Photoreceptor Cells|*Phagocytosis|Retinitis Pigmentosa|Retina|Signal Transduction|Monomeric GTP-Binding Proteins|RAB28 protein, human|rab GTP-Binding Proteins|Rab28 protein, mouse 40 KCNJ13 30022023 Nat Commun 2018 PMC6052067 10.1038/s41467-018-05043-5 6 18 0 30 Mice|Animals|*Potassium|*Muscle, Smooth|Trachea|Smooth Muscle Cell|Actin|Phosphorylation|Kir7.1 channel|*Potassium Channels, Inwardly Rectifying|Muscle Contraction|Signal Transduction|Lungs 40 KCNJ13 30009826 Exp. Eye Res. 2018 PMC6707361 10.1016/j.exer.2018.07.014 6 0 0 30 Humans|Mice|Animals|*Retinal Degeneration|*Retinal Pigment Epithelium|Retina|Electroretinography|Kir7.1 channel|Potassium Channels, Inwardly Rectifying|Disease Models, Animal 40 KCNJ13 29972856 J Neurol Surg A Cent Eur Neurosurg 2018 10.1055/s-0037-1615284 0 0 0 30 *Choroid Plexus|Choroid Plexus Neoplasms|Papilloma, Choroid Plexus|Magnetic Resonance Imaging|*Supratentorial Neoplasms|Diagnosis, Differential 40 KCNJ13 29772553 Front Biosci (Landmark Ed) 2018 0 3 0 30 Swine|Animals|*Indometacin|*Intestinal Diseases|Intestine, Small|Enterocytes|Intestinal Mucosa|Weaning|Dietary Supplements|Animals, Newborn|Disease Models, Animal 40 KCNJ13 29740340 Front Physiol 2018 PMC5925607 10.3389/fphys.2018.00428 2 1 0 30 *Tissue Distribution|Potassium Channels, Inwardly Rectifying|Potassium|Amino Acid Sequence 40 KIAA0586 30120317 Sci Rep 2018 PMC6098120 10.1038/s41598-018-30671-8 0 0 0 86 Animals|*Zebrafish|*Ciliopathy|*Cilia|*Neurites|Talpid3 protein, zebrafish 27 KIAA0586 30120217 J. Med. Genet. 2018 10.1136/jmedgenet-2018-105470 2 0 0 86 Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|*Homozygote|Cerebellum|Retina|Mutations|Exome|Pedigree|High-Throughput Nucleotide Sequencing|Cell Cycle Proteins 27 KIAA0586 29458881 Taiwan J Obstet Gynecol 2018 10.1016/j.tjog.2017.12.021 3 0 0 86 Pregnancy|Female|Humans|Short rib-polydactyly syndrome, Verma-Naumoff type|*Short Rib-Polydactyly Syndrome|*Prenatal Diagnosis|*Mutations|Cytoplasmic Dyneins|*Polydactyly|Fetus|*Ribs|DYNC2H1 protein, human 27 KIAA0586 29396404 Sci Rep 2018 PMC5797153 10.1038/s41598-018-20489-9 5 5 0 86 Animals|Humans|*Zebrafish|*Cilia|*Ciliopathy|Zebrafish Proteins|Retinal Degeneration|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|RAB8A protein, human|rab GTP-Binding Proteins|Basal Bodies|Retinal Photoreceptor Cell Outer Segment|Photoreceptor Cells|Abnormalities, Multiple|Retina|Opsin|Mutations|Protein Transport 27 KLHL7 30300710 Eur J Med Genet 2018 10.1016/j.ejmg.2018.10.003 1 0 0 90 Child|Humans|*Siblings|*Codon, Nonsense|Crisponi syndrome|Facies|Hand Deformities, Congenital|Bohring syndrome|Intellectual Disability|Phenotypes|Craniosynostoses|Hyperhidrosis|Mutations|Homozygote|Trismus|Developmental Disabilities|Abnormalities, Multiple|Pedigree|Syndrome|Death, Sudden 30 KLHL7 30142437 Eur J Med Genet 2018 PMC6386622 10.1016/j.ejmg.2018.08.009 1 0 0 90 Crisponi syndrome|*BTB-POZ Domain|*Hand Deformities, Congenital|*Facies|*Trismus|*Hyperhidrosis|*Death, Sudden|*Phenotypes|*Alleles|Homozygote|*Syndrome|Pedigree|Receptors, Cytokine|Sequencing, Whole Exome|Mutation 30 KLHL7 29633055 Breast Cancer Res. Treat. 2018 10.1007/s10549-018-4777-z 1 0 0 90 Humans|Breast Cancer, Familial|*Breast Neoplasms|Prognosis|Biomarkers, Tumor|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic 30 KLHL7 29435412 FEBS Open Bio 2018 PMC5794457 10.1002/2211-5463.12360 15 2 0 90 miRNAs|Retinal Pigment Epithelium|Oxidative Stress|Retinitis Pigmentosa|Signal Transduction|*Neurons|Epithelial Cells|Retinal Pigments 30 LMOD2 30102883 J. Mol. Cell. Cardiol. 2018 PMC6324932 10.1016/j.yjmcc.2018.08.009 5 0 0 42 Mice|Animals|*Myofibrils|*Actin Cytoskeleton|Sarcomeres|*Cardiac Failure|Muscle Contraction|Muscle Proteins|Myocardium|Muscle, Skeletal|Myocytes, Cardiac|Microfilament Proteins|Mice, Knockout|Cytoskeletal Proteins|Ventricular Dysfunction, Left 19 LMOD3 30291184 Neurology 2018 10.1212/WNL.0000000000006428 3 0 0 46 Humans|Myopathies, Nemaline|Muscle Proteins|Muscle, Skeletal|Mutations, Missense|Mutation|Austria 22 LMOD3 29923248 J Sleep Res 2018 10.1111/jsr.12718 1 0 0 46 Humans|Animals|Mice|*Kleine-Levin Syndrome|HLA-DQ beta-Chains|Brain|Nervous System Diseases 22 LMOD3 29331079 J Ultrasound Med 2018 10.1002/jum.14520 3 0 0 46 *Myopathies, Nemaline|Muscle Proteins|Muscle, Skeletal|Hypotonia|Phenotype|Microfilament Proteins|Mutations|Muscle Weakness|Sequencing, Whole Exome 22 LOXHD1 30267097 Invest. Ophthalmol. Vis. Sci. 2018 10.1167/iovs.18-24590 2 0 0 9 Humans|Russia|*Fuchs Corneal Dystrophy|Transcription Factor 4|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Trinucleotide Repeat Expansion|Genetic Predisposition to Disease|Alleles|Genotype|Polymorphism, Genetic|*Cohort Studies|Polymerase Chain Reaction|Transcription Factors|*Biomarkers|SLC4A11 protein, human|Antiporters|Anion Transport Proteins 34 LOXHD1 30139988 Eur. J. Hum. Genet. 2018 PMC6244407 10.1038/s41431-018-0218-z 7 0 0 9 Humans|*Arabs|Israel|HEK293 Cells|*Hearing Loss|DNA Mutational Analysis|Pedigree|Deafness|Connexins|Homozygote|Exon|Mutation|Myosins|Alleles|Membrane Proteins|OTOF protein, human|TBC1D24 protein, human|Nerve Tissue Proteins 34 LOXHD1 30123251 Neural Plast. 2018 PMC6079373 10.1155/2018/4920980 9 0 0 9 Humans|Nonsyndromic Deafness|*Deafness|*Chinese|Sequencing, Next-Generation|Hearing Loss, Sensorineural|Pedigree|Mutation|Family Members 34 LOXHD1 29799290 Ophthalmic Genet. 2018 10.1080/13816810.2018.1474367 2 0 0 9 Humans|Corneal dystrophy, Fuchs' endothelial, 2|Genome-Wide Association Study|*Fuchs Endothelial Corneal Dystrophy|Transcription Factor 4|Collagen Type VIII|Genetic Predisposition|*Cohort Studies|*Asian Continental Ancestry Group|Intron|Corneal Endothelium|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Single Nucleotide Polymorphisms|Homeodomain Proteins|Pedigree|Trinucleotide Repeat Expansions|Genotype|Transcription Factors|Anion Transport Proteins 34 LOXHD1 29676012 Clin. Genet. 2018 10.1111/cge.13368 4 0 0 9 Humans|*Fuchs' Endothelial Dystrophy|Deafness, Autosomal Recessive 77|*Hearing Loss, Sensorineural|Genotype|Phenotype|Heterozygote|Pedigree|Mutation, Missense|DNA Mutational Analysis|Asian Continental Ancestry Group|Mutation|Genotype-Phenotype Correlations|Carrier Proteins|LOXHD1 protein, human 34 LYPLAL1 29648650 Hum. Mol. Genet. 2018 PMC5985737 10.1093/hmg/ddy124 16 6 0 45 Humans|Adult|Middle Aged|*Non-alcoholic Fatty Liver Disease|*Alleles|Cross-Sectional Studies|Genetic Association Studies|Genetic Predisposition to Disease|Liver|Polymorphism, Single Nucleotide|Lipase|Gene Frequency|Genotypes|Membrane Proteins|Adaptor Proteins, Signal Transducing|European Continental Ancestry Group|TM6SF2 protein, human|GCKR protein, human|LYPLAL1 protein, human|Lysophospholipase 71 LYPLAL1 29487372 Sci Rep 2018 PMC5829219 10.1038/s41598-018-21939-0 7 4 0 45 *Non-alcoholic Fatty Liver Disease|SNPs|Genetic Predisposition to Disease|Lipase|Genetic Association Studies|Liver|Genotypes|Gene Frequency|Membrane Proteins|Adaptor Proteins, Signal Transducing|*Multifactorial Inheritance|Cohort Studies 71 LYPLAL1 29358691 Nat Commun 2018 PMC5778074 10.1038/s41467-017-02380-9 12 4 0 45 Male|Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Genetic Predisposition to Disease|Alleles|Polymorphism, Single Nucleotide|Insulin Sensitivity|Genotype|Genetic Variation|Case-Control Studies|Risk Factors|*X Chromosomes 71 LYPLAL1 29307798 Exp. Mol. Pathol. 2018 PMC6027652 10.1016/j.yexmp.2018.01.001 4 8 0 45 Adult|Humans|Genome-Wide Association Study|Alanine Aminotransferase|Aspartate Aminotransferase|Nonalcoholic Fatty Liver Disease|SNPs|Lipase|Genetic Predisposition to Disease|Genetic Association Studies|Gene Frequency|Alleles|Obesity|Membrane Proteins|Liver|Overweight|Adaptor Proteins, Signal Transducing|Mexico|ADIPOQ protein, human|Adiponectin 71 MYNN 30350386 Genes Chromosomes Cancer 2018 10.1002/gcc.22674 2 0 0 15 Humans|Genome-Wide Association Study|*Colorectal Cancer|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Proportional Hazard Model|Genetic Loci|Prognosis|CDH1 protein, human|Cadherins|Disease-Free Survival|Genotype|Antigens, CD|*Colonic Neoplasms|Risk|MYNN protein, human|Kruppel-Like Transcription Factors 19 MYNN 30120764 Urol J 2018 10.22037/uj.v0i0.4083 1 2 0 15 telomerase RNA|*Urinary Bladder Neoplasms|Telomerase|SNPs|RNA|Genetic Predisposition to Disease|Genotype|Linkage Disequilibrium|Case-Control Studies|Risk|Turkey 19 MYNN 29864683 Bioorg. Chem. 2018 10.1016/j.bioorg.2018.05.024 1 0 0 15 Humans|*BTB-POZ Domain|*Cyclization|*Oncogenes|Repressor Proteins|*Transcription Factors|Neoplasm Proteins|*Oncogenesis|Peptides|*Molecular Conformation|Dimerization|Co-Repressor Proteins|MYNN protein, human|Kruppel-Like Transcription Factors 19 MYNN 29747493 Asian-australas. J. Anim. Sci. 2018 PMC6127594 10.5713/ajas.17.0911 2 0 0 15 Swine|Animals|*Isoforms|Alternative Splicing|Amino Acid Sequence|RNA, Messenger|*Cytoskeletal Proteins 19 MYO3A 30123247 Neural Plast. 2018 PMC6079384 10.1155/2018/4372913 0 0 0 81 Humans|Mice|Animals|Infant|Myosin Type III|Nonsyndromic sensorineural hearing loss|Hearing Loss, Sensorineural|*Hair Cells, Cochlear|*Ear, Inner|*Hearing Loss|Deafness, Autosomal Recessive 30|Stereocilia|Hair Cells, Auditory, Inner|Myosin Heavy Chains|Deafness|*Mutation|Disease Models, Animal|MYO3A protein, human|MYO3A protein, mouse 50 MYO3A 29880844 Sci Rep 2018 PMC5992146 10.1038/s41598-018-26818-2 0 6 0 81 Chlorocebus aethiops|Animals|*Mutation, Missense|Mechanotransduction, Cellular|Myosin Type III|*Hearing Loss|Filopodia|Stereocilia|Myosin Heavy Chains|Actin|COS Cells|Mutation|MYO3A protein, human 50 MYPN 30265593 Physiol. Genomics 2018 10.1152/physiolgenomics.00068.2018 2 0 0 235 Male|Female|Horses|United States|Animals|Genome-Wide Association Study|Belgium|Haplotype|Breeding|Chromosome Mapping|Phenotype|Genotype|*Larynx|Horse Diseases|Polymorphism, Single Nucleotide|Body Size|Mononeuropathy 32 MYPN 30143482 Ann. Clin. Lab. Sci. 2018 0 0 0 235 Humans|*Whole Exome Sequencing|Paroxysmal ventricular fibrillation|*Ventricular Fibrillation|Exome|Mutations|Sudden Cardiac Death|Pedigree|Genetic Predisposition to Disease 32 MYPN 29777134 Sci Rep 2018 PMC5959901 10.1038/s41598-018-26110-3 0 69 0 235 Animals|*Zebrafish|*Myocytes, Cardiac|*Myocardial Contraction|Sarcomeres|Zebrafish Proteins|Myofilament|*Protein Isoforms|Myosin Heavy Chains|Heart Ventricle|Gene Expression Regulation, Developmental|Cell Proliferation 32 OPA3 30114719 Neuropediatrics 2018 10.1055/s-0038-1667345 1 0 0 152 Humans|Infant, Newborn|3-Methylglutaconic Aciduria|*Inborn Errors of Metabolism|Disorders, Mitochondrial|*Epilepsy|*Movement Disorders|3-methylglutaconic acid|Glutarates|Exome|Mutations|*Recognition, Psychology 76 OPA3 29976148 BMC Genet. 2018 PMC6034250 10.1186/s12863-018-0628-5 2 1 0 152 *Sleep, Slow-Wave|DNA Copy Number Variations|*Status Epilepticus|Sleep|Epilepsy|Electroencephalography|Syndromes|Mutations 76 OPA3 29856744 PLoS ONE 2018 PMC5983438 10.1371/journal.pone.0197092 1 5 0 152 Animals|Rats|*Stroke|*Proto-Oncogene Protein c-ets-1|*Brain Ischemia|NRG1 protein, human|*Neuregulin-1|*Transcriptome|Middle Cerebral Artery Occlusion|*Transcriptome Analysis|*Binding Sites|Gene Expression Regulation|Neuroprotective Agents|Neuroprotection|*Promoter Regions, Genetic|Disease Models, Animal|Signal Transduction|Oncogenes 76 OPA3 29801190 Neuropediatrics 2018 10.1055/s-0038-1645884 1 0 0 152 Child|Humans|*Chorea|Dystonic Disorders|Phenotype|Mutation|Adenylyl Cyclases 76 OPA3 29717982 Schweiz. Arch. Tierheilkd. 2018 10.17236/sat00158 0 0 0 152 Cattle|Animals|*Cardiomyopathy, Dilated|Breeding|Cattle Diseases|Pedigree|Genetic Testing|Genotype|Mutation|Switzerland 76 OPA3 29563951 Neuroophthalmology 2018 PMC5858862 10.1080/01658107.2017.1344252 0 0 0 152 Humans|*Wolfram Syndrome|*Genetic Testing|*Mutations|Optic Atrophy, Autosomal Dominant|Optic Atrophy, Hereditary, Leber|GTP Phosphohydrolases|DNA, Mitochondrial|*Optic Nerve Diseases|Proteins 76 PCDH12 30459466 J. Hum. Genet. 2018 10.1038/s10038-018-0541-9 0 0 0 30 Humans|*Cerebellar Ataxia|*Homozygote|*Phenotype|*Dystonia|Craniofacial Abnormalities|Abnormalities, Multiple|*Dystonic Disorders|Intellectual Disability|Musculoskeletal Abnormalities|Pedigree|Muscular Atrophy|PCDH12 protein, human|Cadherins 27 PCDH12 30178464 Ann. Neurol. 2018 PMC6510237 10.1002/ana.25327 2 0 0 30 Child|Humans|*Intellectual Disability|Microcephaly|*Syndrome|Developmental Disabilities|Phenotype|*Abnormalities, Multiple|*Musculoskeletal Abnormalities|Mutation 27 PCDH12 29556033 J. Hum. Genet. 2018 10.1038/s10038-018-0432-0 0 0 0 30 Humans|*Cerebral Palsy|*Epilepsy|Microcephaly|Intellectual Disability|Phenotype|Brain Diseases|Brain|Pedigree|Magnetic Resonance Imaging|Mutation|Syndrome|PCDH12 protein, human|Cadherins 27 PCDH15 30531642 Otol. Neurotol. 2018 10.1097/MAO.0000000000002054 6 0 0 138 Humans|*Usher Syndromes|DNA Mutational Analysis|Sequencing, Next-Generation|Pedigree|Genetic Association Studies|Mutation|Genotype|Nonsyndromic Deafness 204 PCDH15 30527337 Biophys. J. 2018 PMC6302040 10.1016/j.bpj.2018.11.010 0 1 0 138 Animals|Swine|*Dimerization|Mechanotransduction, Cellular|osteoblast cadherin|Cadherins|Hair Cells, Auditory|Ear, Inner|Protein Binding|Protein Multimerization|Protein Precursors|Simulations, Molecular Dynamics|*Membrane 204 PCDH15 30459346 Sci Rep 2018 PMC6244211 10.1038/s41598-018-35085-0 5 0 0 138 Humans|Usher syndrome, type 2A|Usher Syndrome, Type IC|Usher Syndrome, Type IG|*Usher Syndromes|Comparative Genomic Hybridization|*High-Throughput Nucleotide Sequencing|DNA Mutational Analysis|Mutations|Pedigree|Nonsense Mutations|Phenotype|CLRN1 protein, human|Membrane Proteins|Cep250 protein, human|Autoantigens|Cell Cycle Proteins 204 PCDH15 30368385 Int. J. Pediatr. Otorhinolaryngol. 2018 10.1016/j.ijporl.2018.09.008 4 0 0 138 Humans|Auditory neuropathy|*High-Throughput Nucleotide Sequencing|*Hearing Loss, Central|*Mutations|Heterozygote|Pedigree|Membrane Proteins|Phenotype|Chinese|Implantation, Cochlear|OTOF protein, human 204 pdlim3 30468920 Int. J. Biochem. Cell Biol. 2018 10.1016/j.biocel.2018.11.009 4 0 0 60 Humans|*Alternative Splicing|Polypyrimidine Tract-Binding Protein|Heterogeneous-Nuclear Ribonucleoproteins|Exons|RNA Binding Protein|RNA Splicing|Isoforms|TYRP1 protein, human|*Membrane Glycoproteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|HEK293 Cells|LMO7 protein, human|Transcription Factors|LIM Domain Proteins|PTBP1 protein, human|FHOD3 protein, human|Formins 35 PEPD 30066404 FEBS J. 2018 10.1111/febs.14620 2 0 0 553 Humans|*Prolidase Deficiency|proline dipeptidase|PEPD protein, human|*Dipeptidases|Substrate Specificity|Proline|Mutations|Fibroblasts 172 PEPD 29903569 EBioMedicine 2018 PMC6020797 10.1016/j.ebiom.2018.05.033 2 4 0 553 Humans|Adolescent|Child|Young Adult|Adult|Adiponectin|Metabolic Syndrome|H-cadherin|*Cadherins|Asians|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genetic Predisposition to Disease|*Sleep|Genotype|Risk Factors|Beijing 172 PEPD 29650525 Clin Med Res 2018 PMC6108509 10.3121/cmr.2017.1379a 1 0 0 553 *Mast Cells|*Neuroendocrine Tumors|*Flushing|*Mastocytosis|Pheochromocytomas|Thyroid cancer, medullary|Carcinoma, Neuroendocrine|Adrenal Gland Neoplasms|Carcinoid|Endocrine System Diseases|Thyroid Neoplasms|Storm, Thyroid|Paroxysmal Extreme Pain Disorder|Pain|Gastrointestinal Diseases|Rectum 172 PEPD 29374838 Handb Exp Pharmacol 2018 10.1007/164_2017_91 2 0 0 553 Humans|Animals|Erythromelalgia|NAV1.7 Voltage-Gated Sodium Channel|NAV1.8 Voltage-Gated Sodium Channel|NAV1.9 Voltage-Gated Sodium Channel|Pain, Neuropathic|Voltage-Gated Sodium Channels|Sensory Neurons 172 PEPD 29292001 Vet. Microbiol. 2018 10.1016/j.vetmic.2017.11.016 1 0 0 553 Animals|*Vibrio alginolyticus|Vibriosis|Virulence|Gene Expression Regulation, Bacterial|Fish Diseases|Bacterial Proteins|Biofilms|Zebrafish 172 POU5F1B 29928338 Oncol Lett 2018 PMC6004640 10.3892/ol.2018.8567 2 0 0 44 Humans|Female|Middle Aged|*Human Papilloma Virus|*Uterine Cervical Neoplasms|*Papillomavirus Infections|*Cervix Uteri|Virus Integration|DNA, Viral|Carcinoma, Squamous Cell|*Sequencing, Whole Genome|*B-Lymphocytes 19 POU5F1B 29727690 Am. J. Hum. Genet. 2018 PMC5986723 10.1016/j.ajhg.2018.03.019 6 0 0 44 Genome-Wide Association Study|Models, Genetic|Phenotypes|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Genetic Association Studies|Software|Computer Simulation|Transcriptome|Genomics 19 POU5F1B 29620155 Int. J. Oncol. 2018 10.3892/ijo.2018.4341 1 0 0 44 Animals|Humans|POU5F1 protein, human|*Octamer Transcription Factor-3|Nanog Homeobox Protein|Transcription Factor|Homeodomain Proteins|SOXB1 Transcription Factors|MCF-7 Cells|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Neoplastic Stem Cells|Genes, Homeobox 19 POU5F1B 29454285 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.02.023 5 3 0 44 Humans|*Carcinoma, Hepatocellular|*Proto-Oncogene Proteins c-akt|*Liver Neoplasms|Cell Proliferation|Phosphatidylinositol 3-Kinases|Signal Transduction|Gene Expression Regulation, Neoplastic|MicroRNAs|Hep G2 Cells|Apoptosis|Cell Line, Tumor|Upregulation 19 POU5F1B 29435046 Oncol Lett 2018 PMC5778869 10.3892/ol.2017.7677 5 4 0 44 *Stomach Neoplasms|Phosphatidylinositol 3-Kinases|Long Non-Coding RNA|*Apoptosis|*Colon Cancer|*Autophagy|Prognosis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Biomarkers, Tumor|Cell Line, Tumor|Disease Progression|*Stomach|Short Hairpin RNA|Carcinogenesis|Beclin-1 Protein|Up-Regulation|Downregulation 19 PRDM12 30458291 Gene 2018 10.1016/j.gene.2018.11.046 4 1 0 32 Male|Animals|Mice|*Histones|*Methylation|Epigenesis, Genetic|Set2 protein, human|Histone-Lysine N-Methyltransferase|SETD1B protein, human|NSD2 protein, human|KMT2A protein, human|KDM1A protein, human|Histone Demethylases|*Cyprinodontiformes|*Self-Fertilizations|PRDM2 protein, human|KDM5C protein, human|Embryonic Development|*Killifishes|*Reproduction|KMT2D protein, human 32 PRDM12 30347759 Int J Mol Sci 2018 PMC6214140 10.3390/ijms19103250 4 7 0 32 *PR-SET Domains|*Malignancies|*Genome|Transcriptomes|Genomics|Zinc Finger Motifs|Transcription Factors|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Isoforms 32 PRDM12 30071651 Genes (Basel) 2018 PMC6116052 10.3390/genes9080391 1 3 0 32 Humans|Male|Testicular Germ Cell Tumor|Testicular Neoplasms|Cryptorchidism|Spermatogonia|Orchidopexy|Testis|Infertility, Male|Sperm Count|Neoplasms, Germ Cell and Embryonal 32 PRDM12 29949203 Br. J. Dermatol. 2018 10.1111/bjd.16893 0 0 0 32 Humans|Child, Preschool|*Pain Insensitivity, Congenital|*Pain|*Syndrome|Nerve Tissue Proteins|Carrier Proteins|Mutations|*Dermabrasion|*Face|Prdm12 protein, human 32 RNASEH2A 30449034 New Phytol. 2018 10.1111/nph.15597 4 3 0 81 *Oryza|*Reactive Oxygen Species|*B-DNA|*Temperature|Chloroplasts|Gene Expression Regulation, Plant|Plant Proteins|Plant Leaves|Genes, Plant|Phenotype|Chlorophyll|Photosynthesis|*Hot Temperature|*Cell Death|Mutation|Cloning, Molecular|Light|Genetic Complementation Test 41 RNASEH2A 29843367 Int J Mol Sci 2018 PMC6032436 10.3390/ijms19061586 0 0 0 81 *Prognosis|Carcinoma, Renal Cell|Kidney Neoplasms|Biomarkers, Tumor|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|RNA, Messenger 41 RNASEH2A 29740948 Brain Pathol. 2018 10.1111/bpa.12600 2 0 0 81 *Astrocytes|Nervous System Malformations|Autoimmune Diseases of the Nervous System|SAM Domain and HD Domain-Containing Protein 1|three prime repair exonuclease 1|Exodeoxyribonucleases|*Aicardi Syndrome|Ribonuclease H|Phosphoproteins|Adenosine Deaminase|Mutations|Monomeric GTP-Binding Proteins|Interferon-alpha|Epilepsy|Cytokines 41 RNASEH2A 29651323 Dis. Markers 2018 PMC5830953 10.1155/2018/3452739 8 3 0 81 Humans|*Carcinogenesis|Colorectal Cancer|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Regulatory Networks|Protein Interaction Maps|Computational Biology 41 RNASEH2A 29315404 Nucleic Acids Res. 2018 PMC5829647 10.1093/nar/gkx1312 9 17 0 81 Humans|Proteomics|*Long Interspersed Nucleotide Elements|RNA Helicase|Retrotransposon|Moloney Leukemia Virus|Cell Line|Small Hairpin RNA|DNA Replication|Mov10 protein, human 41 rtn2 29310658 J. Biomed. Sci. 2018 PMC5757295 10.1186/s12929-017-0403-3 1 16 0 109 VCP protein, human|*Valosin Containing Protein|*Endoplasmic Reticulum|Hereditary Spastic Paraplegia|Spastin|*Protein Biosynthesis|Membrane Proteins|Adenosine Triphosphatases|Paget's Disease of Bone|Mutations|Frontotemporal Dementia|Membrane Fusion 23 s100a5 30414696 Pathol. Res. Pract. 2018 10.1016/j.prp.2018.10.034 0 0 0 15 *Prognosis|*Stomach Neoplasms|Gene Expression Regulation, Neoplastic|S100 Protein Family|Biomarkers, Tumor|Disease-Free Survival|Kaplan-Meier Estimate|RNA, Messenger 39 s100a5 29858979 World J Pediatr 2018 10.1007/s12519-018-0163-5 1 0 0 15 Adult|Humans|Child|*S100 Protein Family|*Neonatology 39 SERPINA9 30373376 Cartilage 2018 10.1177/1947603518809403 0 1 0 6 Humans|*Mesenchymal Stem Cells|kartogenin|*Cartilage|Cell Differentiation|*Anilides|*Phthalic Acids|Chondrogenesis|Chondrocytes|*Markers, Differentiation|Cells, Cultured|Gene Expression Regulation|Cell Line 19 SH3TC2 30562927 Int J Mol Sci 2018 PMC6320960 10.3390/ijms19124072 3 0 0 139 Mice|Animals|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|*Neuromuscular Junction|*Disease Models, Animal|Mutations 77 SH3TC2 30373780 BMJ Open 2018 PMC6224714 10.1136/bmjopen-2018-021632 3 0 0 139 Inherited Peripheral Neuropathy|*Sequencing, Next-Generation|Charcot-Marie-Tooth Disease|Mutation 77 SH3TC2 30001926 Neuromuscul. Disord. 2018 10.1016/j.nmd.2018.06.004 1 0 0 139 Humans|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|*Prevalence|Norway|*Mutation|Genetic Testing|Genotype|Phenotype|Proteins|Scoliosis 77 SH3TC2 29515423 Case Rep Neurol 2018 PMC5836280 10.1159/000486589 0 1 0 139 Humans|Charcot-Marie-Tooth disease, Type 4C|*Charcot-Marie-Tooth Disease|*Genetic Testing|Mutations|Phenotype|*Asian Continental Ancestry Group 77 SH3TC2 29336362 Chin. Med. J. 2018 PMC5776844 10.4103/0366-6999.222331 0 1 0 139 Humans|Charcot-Marie-Tooth Disease|Mutation|Phenotype|Chinese|Demyelinating Diseases|Cohort Studies|BSCL2 protein, human|GTP-Binding Protein gamma Subunits 77 SH3TC2 29321516 J. Hum. Genet. 2018 10.1038/s10038-017-0388-5 0 0 0 139 Male|Humans|Female|Japan|Charcot-Marie-Tooth Disease|*Mutations|Phenotype|Genotype|Pedigree|SH3TC2 protein, human|Proteins 77 Six5 30282165 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 10.13201/j.issn.1001-1781.2018.16.005 0 0 0 112 113 Six5 30237319 Dis Model Mech 2018 PMC6215434 10.1242/dmm.034611 1 0 0 112 Humans|Mice|Animals|Homeodomain Proteins|Trans-Activators|Homeo Box Genes|Transcription Factors|Muscle Development|Gene Expression Regulation, Developmental 113 Six5 30224242 Reprod. Biomed. Online 2018 10.1016/j.rbmo.2018.08.005 2 0 0 112 Humans|Female|*Hyperandrogenism|*Polycystic Ovary Syndrome|*Long Non-Coding RNA|*Granulosa Cells|Gene Expression Regulation 113 Six5 29608557 PLoS Genet. 2018 PMC5897035 10.1371/journal.pgen.1007222 6 0 0 112 Animals|Humans|*Body Mass Index|*Drosophila melanogaster|*Genome-Wide Association Study|*RNA Interference|SNPs|Obesity|Quantitative Trait Loci|Phenotype|Genetic Predisposition to Disease|Adipose Tissue|Adiposity|ARIH1 protein, human|Carrier Proteins|ZCCHC8 protein, human|Nuclear Proteins|VKORC1 protein, human|Vitamin K Epoxide Reductases 113 Six5 29481865 Mol Plant 2018 10.1016/j.molp.2018.02.011 7 1 0 112 *Fusarium|Tomato|Plant Diseases|Plants, Transgenic|Virulence|Fungal Proteins|Plant Proteins|Tobacco|Arabidopsis|*Cell Movement 113 slamf8 30552382 Cell. Mol. Immunol. 2018 PMC7000402 10.1038/s41423-018-0191-z 3 6 0 45 Mice|Animals|TLR4 protein, human|*Toll-Like Receptor 4|Lipopolysaccharides|*Macrophages|*Downregulation|*Endotoxins|Signal Transduction|Signaling Lymphocytic Activation Molecule Family Receptors|Cytokines|NF-kappa B|*Hepatitis|Kupffer Cells|Mitogen-Activated Protein Kinases|Liver|Inflammation|Tlr4 protein, mouse 19 slamf8 30482849 Sci Signal 2018 10.1126/scisignal.aat7493 2 0 0 45 Mice|Animals|*mTORC2|*Autophagy|Bacterial Outer Membrane Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Salmonella typhimurium|Escherichia coli|Cell Membrane|Mitochondria|*Cytoplasm 19 slamf8 30105842 CNS Neurosci Ther 2018 PMC6488888 10.1111/cns.13041 4 0 0 45 Humans|*Glioma|Brain Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor 19 slamf8 29498772 Exp. Dermatol. 2018 10.1111/exd.13523 2 4 0 45 Humans|*Mastocytosis|*Signal Transduction|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Mast Cells|*Oncogenes|Proto-Oncogene Proteins c-kit|*Oncogenesis|Cell Proliferation|Cell Line, Tumor|Mutation 19 SMPX 30174017 Int. J. Pediatr. Otorhinolaryngol. 2018 10.1016/j.ijporl.2018.07.022 1 0 0 17 Humans|*Hearing Loss|Nonsyndromic Deafness|*Deafness|Nonsyndromic sensorineural hearing loss|Hearing Loss, Sensorineural|*Sequencing, Next-Generation|*Chinese|*Genes, X-Linked|Pedigree|Muscle Proteins|Chromosomes|SMPX protein, human 41 SMPX 30065609 Curr. Genomics 2018 PMC6030855 10.2174/1389202919666171218163046 1 0 0 17 Deafness, X-Linked 5|Genetic Diseases, X-Linked|Progressive hearing loss stapes fixation|*Hearing Loss, Sensorineural|Deafness, X-Linked 4|Deafness, X-Linked 1|Hearing Loss, Conductive|Hearing Loss|Deafness|Phenotype|Pedigree|Genotype|Genes, X-Linked|Mutation|Chromosome Deletion|Vestibulocochlear Nerve Diseases|Cochlear Nerve 41 SMPX 29559740 J. Hum. Genet. 2018 10.1038/s10038-018-0443-x 1 0 0 17 Male|Humans|Nonsyndromic sensorineural hearing loss|*Hearing Loss, Sensorineural|Nonsyndromic Deafness|Deafness|*Chinese|Hearing Loss|Exome|Pedigree|X-Linked Inheritance|Sequencing, Whole Exome|Single Nucleotide Polymorphism|Mutation|Genetic Diseases, X-Linked|China|SMPX protein, human|Muscle Proteins 41 SNX14 30473892 Case Rep Genet 2018 PMC6220403 10.1155/2018/6737938 0 0 0 37 Humans|*Intellectual Disability|*Exome|*Sorting Nexins|*Whole Exome Sequencing|*Cerebellar Diseases|Cerebellar Ataxia|Pedigree|Phenotype|Mutations|Ataxia|Genetic Linkage|Homozygote|Cerebellum|Atrophy 22 SNX14 29635513 Hum. Mol. Genet. 2018 PMC5961352 10.1093/hmg/ddy101 10 0 0 37 Animals|Humans|Spinocerebellar ataxia 20|*Lipid Metabolism|HEK293 Cells|*Endoplasmic Reticulum|Spinocerebellar Ataxias|Lipid Droplets|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Lysosomes|*Mutations|Sorting Nexins|Endosomes|Autophagy|Intermediate Filament Proteins|Cerebellar Ataxia|Homeostasis|Oleate 22 SPATA5 30552426 Eur. J. Hum. Genet. 2018 PMC6460568 10.1038/s41431-018-0299-8 7 0 0 119 Humans|*Whole Exome Sequencing|*DNA Copy Number Variations|Exome|Phenotype|Genetic Testing|Genetic Predisposition to Disease|Mutation|Neurodevelopmental Disorders|Allele|*Heredity|Microarray Analysis|Bioinformatic|Brain Diseases|Cohort Studies|SPATA5 protein, human|ATPases Associated with Diverse Cellular Activities 19 SPATA5 30358834 Hum. Reprod. 2018 10.1093/humrep/dey319 0 0 0 119 Humans|Male|*Infertility, Male|CpG Islands|Sperm|Spermatogenesis|DNA Methylation|Fertility 19 SPATA5 30009132 Mol Genet Metab Rep 2018 PMC6043467 10.1016/j.ymgmr.2018.03.004 0 1 0 119 Humans|*Whole Exome Sequencing|Estonia|*Disorder, Mitochondrial|Exome|Sequence Analysis, DNA|mtDNA|Mutation|Mitochondria 19 SPATA5 29343804 Eur. J. Hum. Genet. 2018 PMC5838984 10.1038/s41431-017-0001-6 4 1 0 119 Humans|Child|Animals|Rats|Microcephaly|Epilepsy|Seizures|Brain Diseases|Phenotype|Intellectual Disability|Developmental Disabilities|Exome|Disease, Mitochondrial|Mutation|Hearing Impairment|Brain|Mitochondrial Dynamics|Cohort Studies|SPATA5 protein, human|ATPases Associated with Diverse Cellular Activities 19 TANGO2 30566259 Head Neck 2018 10.1002/hed.25368 3 0 0 104 Humans|*Papillomavirus Infections|*Oropharyngeal Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Human papillomavirus 16|Head and Neck Neoplasms|Carcinoma, Squamous Cell|*Mouth Neoplasms|DNA, Viral|Viral Load|*Biomarkers|*Virus Diseases 23 TANGO2 30327536 Genet. Med. 2018 10.1038/s41436-018-0336-6 0 0 0 104 *Phenotype|Language 23 TANGO2 30245509 Genet. Med. 2018 PMC6752277 10.1038/s41436-018-0137-y 3 0 0 104 Child|Humans|*Phenotype|Intellectual Disability|Whole Exome Sequencing|Developmental Disabilities|Genotype|Exome|Seizures|Pedigree|Mutation|Encephalopathy 23 taok2 29467497 Mol. Psychiatry 2018 PMC6756231 10.1038/s41380-018-0025-5 0 1 0 143 Humans|Mice|Animals|*Autistic Disorder|RHOA protein, human|*rhoA GTP-Binding Protein|*Signal Transduction|Autism Spectrum Disorders|Synaptic Transmission|Neurogenesis|Dendrites|Neurodevelopmental Disorders|Phosphorylation|Protein-Serine-Threonine Kinases|Synapses|Mice, Knockout|Mutations|Brain|Phenotypes|Cognition 19 TGM6 30287856 Nat Commun 2018 PMC6172286 10.1038/s41467-018-06539-w 4 0 0 55 Humans|*Genome-Wide Association Study|*Asian Continental Ancestry Group|*Tuberculosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Mycobacterium tuberculosis|Pulmonary Tuberculosis|Alleles|Case-Control Studies 22 TGM6 30229425 Cerebellum 2018 PMC6544358 10.1007/s12311-018-0978-6 2 0 0 55 Humans|*Frameshift Mutation|*Spinocerebellar Ataxias|Mutation|Pedigree|Cerebellar Ataxia|Stop Codon, Premature|Transglutaminases|*Hispanic 22 tmem127 30536464 J. Intern. Med. 2018 10.1111/joim.12869 4 0 0 146 Humans|Child|*Pheochromocytoma|Magnetic Resonance Imaging|Whole Body Imaging|*Paraganglioma|*Adrenal Gland Neoplasms|*Genetic Testing|Germ-Line Mutation|Genetic Predisposition to Disease 111 tmem127 30405919 Case Rep Endocrinol 2018 PMC6204204 10.1155/2018/6358485 2 0 0 146 *Pheochromocytoma|*Thyroid Cancer, Papillary|*Paraganglioma|*Adrenal Gland Neoplasms|*Mutation|Germ-Line Mutation|Genetic Predisposition to Disease|Thyroid Neoplasms 111 tmem127 30356369 Case Rep Endocrinol 2018 PMC6176301 10.1155/2018/2091257 1 0 0 146 Female|Humans|Young Adult|Adult|*Pheochromocytoma|*Adrenal Gland Neoplasms|Paraganglioma|Succinate Dehydrogenase|*Cyanosis|Germ-Line Mutation|Genetic Testing|Mutation|Heart Defects, Congenital|*Hypoxia 111 tmem127 30306232 Chirurg 2018 10.1007/s00104-018-0741-z 0 0 0 146 Humans|*Pheochromocytoma|Neoplasm Recurrence, Local|*Adrenal Gland Neoplasms|Paraganglioma|Multiple Endocrine Neoplasia Type 2a|von Hippel-Lindau Disease|Neurofibromatosis 1|Mutations, Germline|Genes, Neurofibromatosis 1|Multiple Endocrine Neoplasia|DNA Mutational Analysis|Mutation|Syndrome 111 tmem127 30213301 Ann. Endocrinol. (Paris) 2018 10.1016/S0003-4266(18)31234-4 0 0 0 146 Humans|*Pheochromocytoma|*Follow-Up Studies|*Paraganglioma|*Adrenal Gland Neoplasms|Succinate Dehydrogenase|Germ-Line Mutation|Genetic Testing|Heterozygote|Genetic Predisposition to Disease|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Mutations|Membrane Proteins 111 TSPEAR 30046887 Hum. Genet. 2018 PMC6165673 10.1007/s00439-018-1907-y 0 0 0 2 Humans|WNT10A protein, human|*Wnt Proteins|PAX9 Transcription Factor|Anodontia|Allele Frequency|Sequencing, Whole Exome|Mutations|Allele|Dentition, Permanent|Cohort Studies|Turkey|BCOR protein, human|Proto-Oncogene Proteins|Repressor Proteins|TSPEAR protein, human|Proteins 19 TSPEAR 29503203 Mol. Ther. 2018 PMC6079370 10.1016/j.ymthe.2018.01.015 0 0 0 2 *Ligands|Immunotherapy, Adoptive|Receptors, Chimeric Antigen|Receptors, Antigen, T-Cell|*T-Cell Receptor Gene|T-Lymphocytes|Cytotoxicity, Immunologic|Adoptive Cell Transfer|peptide B|*Phenotypes|Cytokines|Antigens, Neoplasm|Cell Line, Tumor|Flow Cytometry 19 UNC13A 30404828 J. Cell. Sci. 2018 10.1242/jcs.213017 0 3 0 276 Rats|Animals|Exocytosis|rab3A GTP-Binding Protein|Secretory Vesicles|Membrane Fusion|alpha-Synuclein|Neurons|Presynaptic Terminals|PC12 Cells|Photobleaching|Calcium|Green Fluorescent Proteins 88 UNC13A 30368160 Neurobiol. Aging 2018 PMC6251755 10.1016/j.neurobiolaging.2018.09.031 2 0 0 276 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Frontotemporal Lobar Degeneration|DNA-Binding Proteins|Inclusion Bodies|Nerve Tissue Proteins|*Genetic Polymorphism|Atrophy|Heterozygote|Imaging, Magnetic Resonance 88 UNC13A 29719243 Cell Rep 2018 PMC6436828 10.1016/j.celrep.2018.03.126 5 0 0 276 Animals|*Synapses|Synaptic Vesicle|Drosophila|Drosophila Proteins|Drosophila melanogaster|Presynaptic Terminals|TYRP1 protein, human|*Membrane Glycoproteins|Nerve Tissue Proteins|*Brain 88 UNC13A 29630712 JAMA Neurol 2018 PMC6043387 10.1001/jamaneurol.2018.0372 13 3 0 276 *Frontotemporal Dementia|*Amyotrophic Lateral Sclerosis|*Pick Disease of the Brain|C9orf72 Protein|Supranuclear Palsy, Progressive|Genetic Predisposition to Disease|Genome-Wide Association Study|Motor Neurons|Polymorphism, Single Nucleotide|Nerve Degeneration|*Genetic Selection 88 USB1 30215753 Nucleic Acids Res. 2018 PMC6265477 10.1093/nar/gky812 4 3 0 66 Humans|U6 small nuclear RNA|*snRNA|Spliceosome|Poikiloderma with Neutropenia|Skin Abnormalities|Neutropenia|RNA Splicing|Saccharomyces cerevisiae|Phosphoric Diester Hydrolases|Uridine|Exoribonucleases|Mutations|Adenine Nucleotides|USB1 protein, human 34 USB1 30045688 BMC Infect. Dis. 2018 PMC6060542 10.1186/s12879-018-3246-y 5 6 0 66 *Metformin|*Matrix Metalloproteinases|*Tuberculosis|*Diabetes Mellitus|Hypoglycemic Agents|*Comorbidity|Antitubercular Agents|Tuberculosis, Pulmonary 34 USB1 29797650 Pediatr Blood Cancer 2018 10.1002/pbc.27262 0 0 0 66 Humans|Poikiloderma with Neutropenia|Homozygote|Sequence Deletion|*Skin Abnormalities|*Neutropenia|Rothmund-Thomson Syndrome|DNA Mutational Analysis|Mutations|Pedigree|Skin Diseases|Phosphoric Diester Hydrolases 34 USB1 29770900 J. Clin. Immunol. 2018 10.1007/s10875-018-0508-9 0 0 0 66 Humans|Poikiloderma with Neutropenia|*Skin Abnormalities|*Neutropenia|*Mutation|Phenotype|Genotype|Myelodysplastic Syndromes|Leukemia, Myeloid, Acute|Phosphoric Diester Hydrolases 34 USB1 29753917 Eur J Med Genet 2018 10.1016/j.ejmg.2018.05.007 0 0 0 66 Male|Humans|Female|Poikiloderma with Neutropenia|*Siblings|*Follow-Up Studies|*Skin Abnormalities|*Neutropenia|Phenotype|Mutation|Phosphoric Diester Hydrolases|Syndrome|*Connective Tissue Diseases|*Atrophy 34 USB1 29720095 BMC Infect. Dis. 2018 PMC5932769 10.1186/s12879-018-3116-7 1 0 0 66 Adult|Humans|*Tuberculosis|Tuberculin Test|Latent Tuberculosis|Contact Tracing|Risk Factors|Screening|*Knowledge|Family Characteristics|Surveys and Questionnaires|India 34 USP9Y 30262602 Blood Adv 2018 PMC6177651 10.1182/bloodadvances.2018019513 2 0 0 19 Male|Humans|Female|*Graft vs Host Disease|*Hematopoietic Stem Cell Transplantation|Unrelated Donors|Transplantation Conditioning|Transplantation, Homologous|Histocompatibility|Histocompatibility Testing|HLA-DPB1 antigen|HLA-DP beta-Chains|Hematologic Neoplasms|*Stem Cell Transplantation|Minor Histocompatibility Antigens|Alleles|Disease-Free Survival|Chromosomes 80 USP9Y 30229981 Anim. Genet. 2018 10.1111/age.12723 2 0 0 19 Male|Animals|Cattle|*Haplotypes|*Y Chromosome|Breeding|SNPs|Phylogeny|Genotype|Sequence Analysis, DNA|China 80 USP9Y 29666320 J. Genet. 2018 2 0 0 19 Animals|Cattle|*Camelus|Phylogeny|DNA Copy Number Variations|*Y Chromosome|Microsatellites|Haplotypes|Alleles|Single Nucleotide Polymorphisms|China 80 VPS13C 30376358 Cancer Biother. Radiopharm. 2018 10.1089/cbr.2018.2641 3 6 0 72 Humans|Female|*Up-Regulation|*RNA, Circular|*Carcinoma, Ovarian Epithelial|*Cell Proliferation|*Ovarian Cancer|Cell Movement|Gene Expression Regulation, Neoplastic|Tumorigenesis|MicroRNAs|Cell Line, Tumor|Cell Transformation, Neoplastic|Apoptosis|*Transcriptional Activation|Signal Transduction|VPS13C protein, human|Proteins 43 VPS13C 30245141 Rev. Neurol. (Paris) 2018 10.1016/j.neurol.2018.08.004 11 0 0 72 Male|Humans|Female|*Parkinson Disease|Membrane Proteins|alpha-Synuclein|Parkinsonian Disorders|Mutations|Phenotype|Genetic Predisposition to Disease|Gene Expression|Sequencing, Next-Generation|Lewy Bodies|PLA2G6 protein, human|Group VI Phospholipases A2|RIC3 protein, human|Intracellular Signaling Peptides and Proteins|SPG11 protein, human|Proteins|CHCHD2 protein, human|Transcription Factors 43 VPS13C 30093493 J. Cell Biol. 2018 PMC6168267 10.1083/jcb.201807019 55 3 0 72 Humans|*Transport Proteins|*Mitochondrial Membranes|Endosomes|Vesicular Transport Proteins|Chorea-Acanthocytosis|Lysosomes|*Biological Transport|Endoplasmic Reticulum|Lipid Droplets|Mitochondria|Autophagy|Saccharomyces cerevisiae|*Lipids|Homeostasis|VPS13A protein, human|VPS13C protein, human|Proteins|VPS13 protein, S cerevisiae 43 VPS13C 29770609 Mol Genet Genomic Med 2018 PMC6081235 10.1002/mgg3.411 5 6 0 72 *Blepharospasm|*Whole Exome Sequencing|Dystonia, Focal|Dystonia|Mutation 43 VPS13C 29622492 Neurobiol. Aging 2018 10.1016/j.neurobiolaging.2018.03.005 2 0 0 72 Humans|*Parkinson Disease|Genome-Wide Association Study|*Asian|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|GTP Cyclohydrolase|Alleles|Genetic Loci|Genetic Variation|Case-Control Studies|Risk Factors|Odds Ratio|VPS13C protein, human|Proteins 43 VPS13C 29518281 Ann. Neurol. 2018 10.1002/ana.25204 14 0 0 72 Spastic Ataxia|Optic Atrophy|Spinocerebellar Ataxias|Spastic|Intellectual Disability|*Mutations|Spastic Paraplegia, Hereditary|Cerebellar Ataxia|Pedigree|Phenotype|*Movement Disorders 43 wdfy1 30097850 Mol. Neurobiol. 2018 PMC6476867 10.1007/s12035-018-1287-2 3 7 0 79 Mice|Animals|*Peroxiredoxin VI|*Down-Regulation|*Toll-Like Receptor 4|Neural Stem Cells|*Neurogenesis|Adaptor Proteins, Vesicular Transport|Signal Transduction|Mice, Transgenic|Cytokines|Mice, Inbred C57BL|Cell Differentiation|Prdx6 protein, mouse|Tlr4 protein, mouse 19 wdfy1 29501733 Biochimie 2018 10.1016/j.biochi.2018.02.017 1 8 0 79 *Cyclosporine|*Fibroblasts|*Autophagy|Immunosuppressive Agents|Myocardium|Up-Regulation|Signal Transduction|Fibrosis|*Heart|Cells, Cultured|Downregulation|Collagen Type I|TNF protein, human|Tumor Necrosis Factor-alpha|Cardiomyopathies 19 WDR11 29426865 Nat Commun 2018 PMC5807400 10.1038/s41467-018-02919-4 6 11 0 50 Humans|*Transcription Factor AP-1|trans Golgi Network|Protein Transport|Endosomes|Adaptor Protein Complex 1|Golgi Matrix Proteins|Membrane Proteins|Protein Binding|HeLa Cells|WDR11 protein, human|Proto-Oncogene Proteins 36 5HT1 28661085 Eur. J. Neurosci. 2017 10.1111/ejn.13632 0 0 0 0 Animals|*Dopamine|*Serotonin|*Cyclic AMP|*Phototaxis|*Astacoidea|Receptors, Dopamine|Dopamine Antagonists 176 5HT1 28088734 Biomed. Pharmacother. 2017 10.1016/j.biopha.2017.01.021 1 0 0 0 Mice|Animals|*Diospyros|7-methyljuglone|*Naphthoquinones|*Hypnotics and Sedatives|Anti-Anxiety Agents|Plant Extracts|Phenobarbitone|Plant Roots|Sleep|*In Silico 176 ANKRD26 29222283 Hematology Am Soc Hematol Educ Program 2017 PMC6142591 10.1182/asheducation-2017.1.385 12 0 0 76 Humans|*Thrombocytopenia|Myosin Heavy Chains|Molecular Motor Proteins|Genetic Predisposition to Disease|Nuclear Proteins|Mutation 68 APMAP 28559441 FASEB J. 2017 PMC5566180 10.1096/fj.201601337R 0 23 0 44 Animals|Mice|*Protein-Lysine 6-Oxidase|3T3-L1 Cells|Adipocyte|Adipogenesis|Intra-Abdominal Fat|Diet, High-Fat|Adiposity|TYRP1 protein, human|Membrane Glycoproteins|Insulin Resistance|Obesity 19 APMAP 28161934 Cancer Res Treat 2017 PMC5654148 10.4143/crt.2016.301 3 2 0 44 Humans|*RNA Editing|*RNA|Inosine|*Colorectal Cancer|Sequence Analysis, RNA|Adenosine|High-Throughput Nucleotide Sequencing|*Colonic Neoplasms 19 APMAP 28122643 Arthritis Res. Ther. 2017 PMC5264463 10.1186/s13075-017-1228-x 24 0 0 44 Humans|*Proteomics|*Saliva|*Tear|*Biomarkers|Sjogren's Syndrome|*Extracellular Vesicles|Case-Control Studies|*Lacerations 19 C12orf65 28804760 Neurol Genet 2017 PMC5532748 10.1212/NXG.0000000000000171 1 0 0 45 Humans|*Autopsy|Homozygote|Diagnosis, Differential 26 C12orf65 28639102 Sci China Life Sci 2017 10.1007/s11427-017-9080-y 10 0 0 45 Child|Humans|*Disorders, Mitochondrial|Leigh Syndrome|DNA, Mitochondrial|Encephalomyopathy, Mitochondrial|Sequencing, Next-Generation|Mutation|Mitochondria|Phenotype|Retrospective Studies|Stroke|*Chromosome Structures|China 26 CADPS2 29201482 Case Rep Psychiatry 2017 PMC5671701 10.1155/2017/4254152 1 0 0 67 Humans|*Autism Spectrum Disorder|Genome-Wide Association Study|*Syndrome|*Chromosome Structures|*Databases, Genetic|Autistic Disorder|*Chromosomes, Human|Disorder, Neurodevelopmental|Language|Communication|*Precipitating Factors|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins 37 CADPS2 28971736 World J. Biol. Psychiatry 2017 10.1080/15622975.2017.1386324 1 0 0 67 37 CADPS2 28647363 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.06.134 4 2 0 67 *alpha-Synuclein|*Gene Expression|*Diagnostic Tests, Routine|*Biochemical Phenomena 37 CADPS2 28072833 PLoS ONE 2017 PMC5225008 10.1371/journal.pone.0169935 10 0 0 67 Humans|*Translocation, Genetic|*Phenotypes|*Sequencing, Whole Genome|Chromosome Breakpoints|Chromosome Mapping|Base Sequence|Chromosome Aberrations|In Situ Hybridization, Fluorescence|Next Generation Sequencing|Heterozygote|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins|PTCD1 protein, human|Mitochondrial Proteins 37 CADPS2 28041965 Neurosci. Lett. 2017 10.1016/j.neulet.2016.12.068 2 1 0 67 Animals|Mice|*Biochemical Phenomena|*Diagnostic Tests, Routine|*Gene Expression 37 CDKN2AIP 28754531 Mech. Ageing Dev. 2017 10.1016/j.mad.2017.07.008 1 6 0 154 *Cellular Senescence|*Cell Proliferation|p53 Tumor Suppressor Protein|*Carcinogenesis|p14ARF|Proto-Oncogene Proteins c-mdm2|Cyclin-Dependent Kinase Inhibitor p21|Apoptosis Regulatory Proteins|Apoptosis|DNA Damage|Cell Line, Tumor|Transcription Factors|Signal Transduction 19 CERKL 29068140 Acta Ophthalmol 2017 10.1111/aos.13551 3 0 0 65 Humans|Finland|*Retinal Dystrophy|DNA Mutational Analysis|Pedigree|Homozygote|Electroretinography|Eye Proteins|Mutation|Phenotype 57 CERKL 28600059 Taiwan J Obstet Gynecol 2017 10.1016/j.tjog.2017.04.026 0 0 0 65 Pregnancy|Female|Humans|*Nuchal Translucency Measurement|Amniocentesis|Prenatal Diagnosis|*Syndactyly|Comparative Genomic Hybridization|Chromosome Deletion|Abnormalities, Multiple|*Chromosome Structures|*Transcription Factors|HOXD13 protein, human|Homeodomain Proteins|ZNF804A protein, human|Kruppel-Like Transcription Factors 57 CERKL 28398482 Hum. Mol. Genet. 2017 10.1093/hmg/ddx137 6 2 0 65 Humans|Animals|*Cone-Rod Dystrophies|*Zebrafish|*Gene Knockout Techniques|Retinal Degeneration|Photoreceptors, Cone|Retina|Zebrafish Proteins|Retinitis Pigmentosa|Retinal Pigment Epithelium|*Phagocytosis|*Cilia|MERTK|Mutations|Disease Models, Animal|Cerkl protein, zebrafish|Phosphotransferases (Alcohol Group Acceptor) 57 CERKL 28130426 Physiol. Genomics 2017 PMC5407181 10.1152/physiolgenomics.00096.2016 7 0 0 65 *Pedigree|*Retinal Degeneration|*Exome|*Whole Exome Sequencing|*Genetic Association Studies|*Genetic Testing|DNA Mutational Analysis|Phenotype|Genes, Recessive|Mutations|Genotype|Eye Proteins|Electroretinography 57 CIB2 29255404 Front Mol Neurosci 2017 PMC5722843 10.3389/fnmol.2017.00401 9 10 0 387 Mice|Animals|Hair Cells, Auditory|Hearing Loss, Sensorineural|Calcium-Binding Proteins|Deafness|Pedigree|Membrane Proteins|EF Hand|Cib2 protein, mouse 44 CIB2 29112224 Clin. Genet. 2017 PMC5851821 10.1111/cge.13170 6 4 0 387 Humans|Deafness, Autosomal Recessive 48|Usher Syndrome|Mutation|Pedigree|Calcium-Binding Proteins|Frameshift Mutation|Mutation, Missense|Cohort Studies|CIB2 protein, human 44 CIB2 29086887 Biochem. Genet. 2017 10.1007/s10528-017-9828-3 1 2 0 387 Humans|*Genetic Counseling|*Genetic Testing|*Mutations|*Phenotype|Connexin 26|Connexins|Deafness|Alleles|Gene Frequency|Genotype|Exons|Heterozygote|Audiometry, Pure-Tone|Base Sequence|CIB2 protein, human|Calcium-Binding Proteins 44 CIB2 29084757 EMBO Mol Med 2017 PMC5709726 10.15252/emmm.201708087 10 12 0 387 Nonsyndromic Deafness|*Mechanotransduction, Cellular|Deafness, Autosomal Recessive 48|Usher Syndromes|Hair Cells, Auditory, Inner|Calcium-Binding Proteins|Mutation 44 CIB2 28902924 Braz. J. Med. Biol. Res. 2017 PMC5597282 10.1590/1414-431X20176177 0 13 0 387 Humans|Male|Sheep|Cattle|Mice|Dogs|Horses|Animals|Phylogeny|Iran|Sequences, Nucleotide|Amino Acid Sequence|Sequence Alignment|Goat|Sheep, Domestic|Calcium-Binding Proteins|cDNA|Testis|PCR 44 CIB2 28729416 Cancer Res. 2017 10.1158/0008-5472.CAN-17-0025 8 10 0 387 Humans|Female|sphingosine kinase|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Phosphotransferases (Alcohol Group Acceptor)|*Oncogenesis|*Oncogenes|*Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Xenograft Model Antitumor Assays|Tumor Cells, Cultured|Biomarkers, Tumor|Plasma Membrane|CIB2 protein, human|Calcium-Binding Proteins 44 CIB2 28663585 Nat Commun 2017 PMC5491523 10.1038/s41467-017-00061-1 26 26 0 387 Humans|Mice|Animals|*Mechanotransduction, Cellular|*Hair Cells, Auditory|Stereocilia|Hair Cells, Auditory, Inner|Usher Syndrome|Membrane Proteins|Hearing|Mutation|Protein Transport|Hearing Tests|Biophysical Phenomena|TMC1 protein, human|CIB2 protein, human|Calcium-Binding Proteins|TMC1 protein, mouse|Cib2 protein, mouse|TMC2 protein, mouse 44 DDRGK1 29044990 Environ. Toxicol. 2017 10.1002/tox.22494 0 0 0 145 Mice|Humans|Animals|*Transcriptome Analysis|Sequence Analysis, RNA|*Phototoxicity|Oligonucleotide Array Sequence Analysis|Transcriptome|*Ultraviolet Rays|SMARCC2 protein, human|Transcription Factors|Gene Regulatory Networks|Up-Regulation|Downregulation|Retina|Signal Transduction|Real-Time Polymerase Chain Reaction|Cluster Analysis|Gene Ontology|ATF7 protein, human|Activating Transcription Factors 19 DDRGK1 28263186 J. Clin. Invest. 2017 PMC5373861 10.1172/JCI90193 8 5 0 145 Humans|Mice|Animals|SOX9 protein, human|*SOX9 Transcription Factor|Chondrogenesis|Type II Collagen|Cartilage|Spondyloepimetaphyseal Dysplasia, Shohat Type|*Osteochondrodysplasias|Pyle disease|Chondrocytes|Limb Bud|*Ubiquitination|Gene Expression Regulation, Developmental|Donor Site, Splice|Cells, Cultured|Mutation|Sox9 protein, mouse 19 DDRGK1 28128204 Nat Commun 2017 PMC5290148 10.1038/ncomms14186 20 53 0 145 *Endoplasmic Reticulum|Unfolded Protein Response|Endoplasmic Reticulum Stress|X-Box Binding Protein 1|Endoribonucleases|Signal Transduction|Protein-Serine-Threonine Kinases|Apoptosis|Transcription Factors|Cell Survival|*Homeostasis|Hematopoietic Stem Cells 19 DDRGK1 28104585 Am. J. Physiol. Gastrointest. Liver Physiol. 2017 10.1152/ajpgi.00176.2016 0 4 0 145 Rats|Mice|Animals|*Pancreas, Exocrine|Endoplasmic Reticulum Stress|Endoplasmic Reticulum|Unfolded Protein Response|Acinar Cells|Pancreas|molecular chaperone GRP78|Heat-Shock Proteins|Apoptosis|Amylase|Trypsin|E3 Ligase 19 ddx3y 29230367 PeerJ 2017 PMC5724404 10.7717/peerj.4133 0 0 0 71 Humans|*Transcriptome Analysis|Sequencing, RNA|Oligonucleotide Array Sequence Analysis|Transcriptome|High-Throughput Nucleotide Sequencing|RNA|Base Sequence 104 ddx3y 29170508 Sci Rep 2017 PMC5701018 10.1038/s41598-017-15593-1 1 0 0 71 Animals|*Haplotypes|*Goat|Switzerland|*Y Chromosome|*Breeding|Microsatellite Repeats|Genetic Variation|DNA, Mitochondrial|Genotype|Gene Flow|Phylogeny|Sequence Analysis, DNA|Single Nucleotide Polymorphisms|Southern Europe|Africa|Spain|Italy|Near East 104 ddx3y 29152098 Oncotarget 2017 PMC5675650 10.18632/oncotarget.20916 3 10 0 71 Male|Mice|Animals|*Sertoli Cells|Mequindox|Spermatogenesis|Testis|*Quinoxalines|Blood-Testis Barrier|*Y-Chromosome Genes|Leydig Cells|Organ Size|*Reproduction|Y Chromosome|China 104 ddx3y 28853286 J. Proteome Res. 2017 10.1021/acs.jproteome.7b00391 6 0 0 71 Humans|Male|Female|Chromosomes, Human, Y|TYRP1 protein, human|*Membrane Glycoproteins|*Organogenesis|*Cell Differentiation|Sex Chromosomes|Transducin|TBL1Y protein, human|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 104 ddx3y 28732082 PLoS ONE 2017 PMC5521774 10.1371/journal.pone.0181204 3 0 0 71 Child|Humans|Prospective Studies|*Osteosarcoma|*Sarcoma|*Genomics|*Databases, Factual|*Soft Tissue Neoplasms|Bioinformatics|Tissue Banks|*In Silico|Biomarkers, Tumor|Researchers|*Data Management|Ohio 104 ddx3y 28190795 Biosci Trends 2017 10.5582/bst.2016.01216 4 1 0 71 Male|Humans|Mice|Animals|Human Induced Pluripotent Stem Cells|Testes|Azoospermia|Spermatogenesis|Spermatogonia|DEAD-box RNA Helicases|*Cell Differentiation|Transcription, Genetic|Chromosomes, Human, Y|Minor Histocompatibility Antigens|*Reproduction|DDX3Y protein, human|Ddx3x protein, mouse|RNA Helicases 104 DISP1 28776573 Mod. Pathol. 2017 10.1038/modpathol.2017.60 6 1 0 24 Humans|*Pancreatic Intraductal Neoplasms|Phosphatidylinositol 3-Kinases|Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|Pancreatic Neoplasms|Adenocarcinoma, Mucinous|Adenocarcinoma, Papillary|Chromogranins|DNA Mutational Analysis|Carcinoma, Papillary|GTP-Binding Protein alpha Subunits, Gs|Mutations|Immunohistochemistry|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Mucin|Sequencing, Next-Generation|Biomarkers, Tumor 34 DNAI1 29148062 Biol. Cell 2017 10.1111/boc.201700052 2 0 0 22 Trypanosoma brucei brucei|Flagella|*Trypanosomes|Protozoan Proteins|Dyneins|Cilia|Organelles|RNA Interference 64 DNAI1 29113992 Development 2017 PMC5769618 10.1242/dev.152314 9 0 0 22 Animals|Mice|*Axonemal Dyneins|Axoneme|Zebrafish|Zebrafish Proteins|Cilia|Molecular Chaperones|HSP90 Heat-Shock Proteins|AAA ATPases|Cell Movement|pontin protein, zebrafish|reptin protein, zebrafish 64 DNAI1 28939216 Auris Nasus Larynx 2017 10.1016/j.anl.2017.09.007 8 0 0 22 Humans|Japan|*Sequencing, Next-Generation|Kartagener Syndrome|Axonemal Dyneins|Genetic Testing|Sequence Analysis, DNA|Mutation|Cilia 64 DNAI1 28801648 Sci Rep 2017 PMC5554225 10.1038/s41598-017-08510-z 6 0 0 22 Humans|*Whole Exome Sequencing|*Homozygote|Axonemal Dyneins|Kartagener Syndrome|Mutations|Heterogeneities, Genetic|Proteins|Cilia|High-Throughput Nucleotide Sequencing 64 DNAI2 29113992 Development 2017 PMC5769618 10.1242/dev.152314 0 0 0 30 Animals|Mice|*Axonemal Dyneins|Axoneme|Zebrafish|Zebrafish Proteins|Cilia|Molecular Chaperones|HSP90 Heat-Shock Proteins|AAA ATPases|Cell Movement|pontin protein, zebrafish|reptin protein, zebrafish 30 DNAI2 28676722 Sci Rep 2017 PMC5496876 10.1038/s41598-017-04639-z 2 4 0 30 Mice|Humans|Animals|Child|*Otitis Media|*Mucosa|Notch Receptors|Middle Ear|*Signal Pathway|JAG1 protein, human|Jagged-1 Protein|Haemophilus influenzae|Haemophilus Infections|Goblet Cell|NOTCH3 protein, human|Receptor, Notch3|Disease Models, Animal|Epithelium|Inflammation|Mucin 5AC|Hyperplasia|Metaplasia 30 DRC1 29167384 Mol. Biol. Cell 2017 PMC5909927 10.1091/mbc.E17-08-0510 10 19 0 38 Humans|*Dyneins|*Axoneme|*Microtubule-Associated Proteins|Kartagener Syndrome|Flagella|Cilia|*Cytoskeleton|Algal Proteins|Chlamydomonas reinhardtii|SERPINE1 protein, human|*Plasminogen Activator Inhibitor 1|Mutations|Amino Acid Sequence 45 FAM111A 29073591 Horm Res Paediatr 2017 10.1159/000480505 2 0 0 19 Humans|Insulin-Like Growth Factor I Deficiency|*Insulin-Like Growth Factor I|*Whole Exome Sequencing|*Growth Disorders|Exome|*Hearing Loss, Sensorineural|Heterozygote|Sequencing, Next-Generation|Dwarfism, Pituitary|Pedigree|Mutation 19 FAM111A 28639897 Tumour Biol. 2017 10.1177/1010428317711895 4 0 0 19 Humans|Female|*Uterine Cervical Neoplasms|Neoplasm Recurrence, Local|Neoplasm Invasiveness|Cell Proliferation|Cell Movement|Prognosis|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|HeLa Cells|*Neoplastic Processes|Cell Line, Tumor 19 FAM111A 28320935 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5389286 10.1073/pnas.1700678114 7 1 0 19 Animals|Humans|*Orthopoxvirus|IRF2 protein, human|*Interferon Regulatory Factor 2|*Serine|Vaccinia virus|Viral Proteins|*Host Range|Virus Replication|C3 protein, human|*Complement C3|Serpins|Cell Line|PRSS1 protein, human|*Trypsin|siRNA|RFC3 protein, human|Replication Protein C|FAM111A protein, human 19 FAM111A 28138333 Int J Pediatr Endocrinol 2017 PMC5264330 10.1186/s13633-016-0041-7 2 6 0 19 Child|Humans|Kenny-Caffey syndrome, type 2|*Dwarfism|*Hyperostosis, Cortical, Congenital|*Hypocalcemia|*Hypoparathyroidism|Abnormalities, Multiple|Mutation|Phenotype|Diabetes Mellitus, Type 2 19 FAT2 31966517 Int J Clin Exp Pathol 2017 PMC6966061 0 0 0 52 *Stomach Neoplasms|*Prognosis|Neoplasm Staging|Biomarkers, Tumor|Lymphatic Metastasis|Disease Progression 58 FAT2 29176774 PLoS Genet. 2017 PMC5720821 10.1371/journal.pgen.1007107 7 5 0 52 Animals|Female|*Actomyosin|*Rotation|*Epithelial Tissue|Drosophila Proteins|Drosophila melanogaster|Drosophila|Cell Polarity|*Actin Cytoskeleton|Cadherins|Cells, Epithelial|Oogenesis|Ovarian Follicle|Ovum|Fat2 protein, Drosophila 58 FAT2 29053796 Brain 2017 10.1093/brain/awx251 15 0 0 52 *Exome|*Ataxia, Spinocerebellar|*Whole Exome Sequencing|Pedigree|Mutation|Cohort Studies 58 FAT2 29045826 Cell Rep 2017 PMC5661965 10.1016/j.celrep.2017.09.083 5 7 0 52 Animals|Female|*Rotation|Drosophila|Drosophila Proteins|Drosophila melanogaster|Ovarian Follicle|Oogenesis|Morphogenesis|Ovum|Cell Polarity|Cell Motility|Basement Membrane|Extracellular Matrix|*B-Lymphocytes|Fat2 protein, Drosophila 58 FAT2 28673244 BMC Genomics 2017 PMC5496318 10.1186/s12864-017-3906-0 22 0 0 52 *Cancer|*Genomics|*Oncogenes|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Databases, Genetic|*Gene Expression|Biomarkers, Tumor 58 FAT2 28292425 Dev. Cell 2017 PMC5354100 10.1016/j.devcel.2017.02.003 17 8 0 52 Animals|*Cell Migration|Cell Polarity|Drosophila Proteins|Drosophila melanogaster|*Cell Signaling|Cadherins|Drosophila|Cells, Epithelial|Epithelium|Lar protein, Drosophila|Receptor-Like Protein Tyrosine Phosphatases|Fat2 protein, Drosophila 58 FAT2 28292420 Dev. Cell 2017 10.1016/j.devcel.2017.02.025 2 0 0 52 Female|Animals|*Dancing|*Cell Migration|Drosophila|Drosophila Proteins|Drosophila melanogaster|Cell Polarity|Cadherins|Ovarian Follicle|Ovum|Signal Transduction|Epithelial Cells|Lar protein, Drosophila|Receptor-Like Protein Tyrosine Phosphatases|Fat2 protein, Drosophila 58 FKTN 29101272 Neurology 2017 PMC5719925 10.1212/WNL.0000000000004720 0 0 0 124 Humans|*Muscle Weakness|Muscular Dystrophy, Duchenne-Becker|Dystroglycans|*Paresis|Muscle, Skeletal|Mutation 146 FKTN 28815891 Am. J. Med. Genet. A 2017 PMC6205885 10.1002/ajmg.a.38393 2 3 0 124 Humans|Female|Pregnancy|*Walker-Warburg Syndrome|*Siblings|*Mutation|Mannosyltransferases|Muscular Dystrophies|Eye Abnormalities|Phenotype|Brain|*Cystic Kidneys|Magnetic Resonance Imaging|*Fetus|Missense Mutation|*Prenatal Care|Hydrocephalus|Biological Variation, Population 146 FKTN 28749478 Genet. Med. 2017 10.1038/gim.2017.111 11 0 0 124 Humans|Female|Pregnancy|*Autopsy|Whole Exome Sequencing|Exome|Phenotypes|Sequence Analysis, DNA|Mutation|Chromosome Mapping|Genetic Predisposition to Disease|DNA|Fetus|Cohort Studies|KRIT1 protein, human|KRIT1 Protein|FCRL4 protein, human|Receptors, Fc|WDR81 protein, human|Nerve Tissue Proteins 146 frem1 29197384 BMC Urol 2017 PMC5712187 10.1186/s12894-017-0300-9 0 8 0 54 Humans|Male|*Cryptorchidism|*Urinary Tract|*Kidney|Allanson Pantzar McLeod syndrome|Urogenital Abnormalities|Vesico-Ureteral Reflux|Sequencing, Whole Exome|Hydronephrosis|Urologic Diseases|Pedigree|End Stage Renal Disease|Polymorphism, Single Nucleotide|Mutation|Kidney Tubules, Proximal|*Signal Transduction 58 frem1 28920098 JACC Basic Transl Sci 2017 PMC5582195 10.1016/j.jacbts.2017.03.014 2 10 0 54 *Signal Transduction|Receptor, Interleukin 1|IL1R1 protein, human|Receptor Type I, Interleukin-1|NF-kappa B 58 frem1 28500053 G3 (Bethesda) 2017 PMC5499117 10.1534/g3.117.042655 4 9 0 54 Cattle|Animals|*Genome, Mitochondrial|Nuclear Transfer Techniques|*Embryo Development|DNA, Mitochondrial|Blastocysts|Oocyte|Mitochondria 58 frem1 28441456 PLoS ONE 2017 PMC5404842 10.1371/journal.pone.0176566 20 0 0 54 Humans|Animals|Mice|*Genome-Wide Association Study|Phenotype|Single Nucleotide Polymorphisms|*Face|Genotype|Asian Continental Ancestry Group|European Continental Ancestry Group|Genetic Loci|Intron 58 frem1 28111185 Eur J Med Genet 2017 10.1016/j.ejmg.2017.01.005 3 0 0 54 Humans|Manitoba|Hypertelorism|*Anal Canal|Coloboma|*Syndrome|*Mutation|Phenotype|Abnormalities, Multiple|Pedigree|Extracellular Matrix Proteins 58 FRMD7 29145603 JAMA Ophthalmol 2017 PMC6583550 10.1001/jamaophthalmol.2017.4859 5 0 0 40 Humans|*Sequencing, Next-Generation|Nystagmus, Congenital|DNA Mutational Analysis|Eye Proteins|*Nystagmus, Pathologic|Genetic Testing|Pedigree|Cytoskeletal Proteins|Membrane Proteins|Mutation|Membrane Glycoproteins 79 FRMD7 28962155 Exp Ther Med 2017 PMC5609196 10.3892/etm.2017.4730 1 0 0 40 Humans|*FERM Domains|X-Linked Infantile Nystagmus|Nystagmus, Congenital|Cytoskeletal Proteins|Genetic Diseases, X-Linked|*Cell Lines|Membrane Proteins|Mutations|Neurons|FRMD7 protein, human 79 FRMD7 28764992 Neuropharmacology 2017 10.1016/j.neuropharm.2017.07.030 2 0 0 40 Animals|Child|succinic semialdehyde dehydrogenase deficiency|Succinate-Semialdehyde Dehydrogenase|Amino Acid Metabolism, Inborn Errors|gamma-Aminobutyric Acid|Developmental Disabilities|Rett Syndrome|Autism|Phenotype|Sodium Oxybate|Genetic Association Studies|*Central Nervous System Diseases 79 FRMD7 28656292 Mol Med Rep 2017 PMC5562100 10.3892/mmr.2017.6824 2 0 0 40 Child|Humans|X-Linked Infantile Nystagmus|*Nystagmus, Congenital|*Genetic Diseases, X-Linked|*Chinese|DNA Mutational Analysis|Pedigree|Cytoskeletal Proteins|Mutation|Base Sequence|Membrane Proteins|Exons|Phenotype|Introns|China|FRMD7 protein, human 79 FRMD7 28623544 Sci China Life Sci 2017 10.1007/s11427-017-9089-5 3 0 0 40 Child|Infant|Humans|Retrospective Studies|*Nystagmus, Pathologic|Nystagmus, Congenital|*Mutations|DNA Mutational Analysis|Genetic Diseases, X-Linked|Cytoskeletal Proteins|Genetic Testing|Membrane Proteins|Pedigree|Mutations, Missense|Frameshift Mutation|Stereopsis|FRMD7 protein, human 79 FSCN2 29016529 Retin Cases Brief Rep 2017 10.1097/ICB.0000000000000638 0 0 0 24 Humans|fascin|*Cone Dystrophy|*Microfilament Proteins|*Carrier Proteins|*Mutation|Electroretinography|Retinal Cone Photoreceptor Cells|Retinal Degeneration|Fluorescein Angiography|Tomography, Optical Coherence|Visual Acuity 34 FSCN2 28216641 Sci Rep 2017 PMC5317003 10.1038/srep43062 6 12 0 24 Humans|Mice|Animals|*CRISPR-Cas Systems|Retinitis Pigmentosa|*Photoreceptor Cells|RNA, Messenger, Splicing|Genes, Dominant|Mutation|Spliceosome|*Mutagenesis|Retinal Degeneration|*CRISPR|Retinal Photoreceptor Cells|Carrier Proteins|RP9 protein, human|Proteins 34 FUCA1 29276373 Cancer Inform 2017 PMC5734428 10.1177/1176935117747259 1 54 0 69 *Glycosylation|*Antitumor Agents|Cell Line, Tumor|Gene Expression Regulation, Neoplastic 69 FUCA1 29170530 Sci Rep 2017 PMC5700972 10.1038/s41598-017-16325-1 6 2 0 69 Humans|*Xanthomonadaceae|Phylogeny|Virulence|Plant Diseases|Citrus|Gene Expression Regulation, Bacterial|Host-Pathogen Interactions|Bacterial Proteins|*Biological Evolution|Plant Leaves|Bacteria 69 FUCA1 29109100 Cancer Genomics Proteomics 2017 PMC6070321 10.21873/cgp.20060 1 0 0 69 Humans|Female|*Proteomics|*Uterine Cervical Neoplasms|*Proteases|Human papillomavirus 16|*Endopeptidases|Cell Line, Tumor|Bioinformatics|Carcinogenesis 69 FUCA1 29050215 Oncotarget 2017 PMC5642490 10.18632/oncotarget.17279 6 7 0 69 Humans|*Urinary Bladder Neoplasms|*Proteomics|Cell Proliferation|Eukaryotic Initiation Factor-3|Gene Expression Regulation, Neoplastic|Cell Movement|G2 Phase Cell Cycle Checkpoints|Cell Line, Tumor|Signal Transduction|PGRMC1 protein, human|Membrane Proteins|Receptors, Progesterone|EIF3D protein, human 69 FUCA1 28731163 Int. J. Oncol. 2017 PMC5564410 10.3892/ijo.2017.4077 0 1 0 69 *Tumor Suppressor Protein p53|*Thyroid Cancers|Anaplastic Thyroid Cancer|Papillary Thyroid Cancer|Carcinoma, Papillary|Thyroid Gland|Fucosidase|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|mRNA 69 FUCA1 28440416 Int. J. Oncol. 2017 10.3892/ijo.2017.3968 3 1 0 69 *Fucosidase|*Tumor Suppressor Protein p53|*Thyroid Cancer|Anaplastic Thyroid Cancer|Papillary Thyroid Cancer|Carcinoma, Papillary|Thyroid Gland|Gene Expression Regulation, Neoplastic|Cell Proliferation|mRNA|Mutation|Fucose 69 FUCA1 28238202 Metab Brain Dis 2017 10.1007/s11011-017-9968-5 4 1 0 69 Humans|*Fucosidosis|*Brain Diseases|alpha-L-Fucosidase|Brain|*Nervous System Malformations|Hematopoietic Stem Cell Transplantation|*Neurodevelopmental Disorders|Disease Progression 69 GNPTG 29170090 Gene 2017 10.1016/j.gene.2017.11.052 3 0 0 56 Humans|Child|Mucolipidosis III Gamma|*Mucolipidoses|UDP-N-acetylglucosamine-lysosomal-enzyme-N-acetylglucosaminephosphotransferase|Transferases (Other Substituted Phosphate Groups)|Genotype|Mutations|Phenotype|Genotype-Phenotype Correlation|Mutation, Missense|GNPTG protein, human 50 GNPTG 28950892 Pediatr Rheumatol Online J 2017 PMC5615433 10.1186/s12969-017-0200-2 2 0 0 56 *High-Throughput Nucleotide Sequencing|*Mutations|Mucolipidoses|Transferases (Other Substituted Phosphate Groups)|Pedigree|Genotype 50 GSDMC 28826527 Adv. Immunol. 2017 10.1016/bs.ai.2017.06.001 14 4 0 11 Humans|Mice|Animals|Genome-Wide Association Study|*Asthma|Remodelling, Airway|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Membrane Proteins|Lung|Neoplasm Proteins|Gene Expression|Genotype|Phenotype|Unfolded Protein Response|Chemokines|*Chromosome|ORMDL3 protein, human|GSDMA protein, human|GSDMD protein, human|GSDMB protein, human 19 GSDMC 28223688 Nat Commun 2017 PMC5322534 10.1038/ncomms14265 5 0 0 11 *Sciatica|Genome-Wide Association Study|Intervertebral disc disease|*Intervertebral Disc Displacement|*Intervertebral Disc Degeneration|Lumbar Vertebrae|Diskectomy|Low Back Pain|Alleles|Polymorphism, Single Nucleotide|Genotype 19 HEPACAM 29287594 J Transl Med 2017 PMC5747948 10.1186/s12967-017-1370-x 18 18 0 129 Humans|*Brain Cancer|Receptor, ErbB-2|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Prognosis|Transcriptome 70 HEPACAM 29180230 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.11.020 16 0 0 129 *Glucocorticoids|Corticosterone|Receptors, Glucocorticoid|DUSP1 protein, human|Dual Specificity Phosphatase 1|Cortisol|CXXC5 protein, human|Carrier Proteins|Transcriptomes|Transcription Factors|Signal Transduction|Up-Regulation|*Nervous System Physiological Phenomena|mRNA|Brain 70 HEPACAM 29079544 Eur J Med Genet 2017 10.1016/j.ejmg.2017.10.013 4 2 0 129 Animals|Mice|Humans|Megalencephalic leukoencephalopathy with subcortical cysts|*Retrospective Studies|*Hereditary Central Nervous System Demyelinating Diseases|*Cysts|Membrane Protein|ClC-2 chloride channels|Chloride Channels|Astrocytes|Mutations|Cell Cycle Proteins|Cells, Glial|Brain|Macrocephaly|Protein Transport|HEK293 Cells|White Matter|Trpv4 protein, mouse|TRPV Cation Channels 70 HEPACAM 28244854 Oncol. Res. 2017 10.3727/096504016X14813914187138 3 6 0 129 *Colorectal Cancer|Cell Proliferation|Wnt Signaling Pathway|Cell Movement|beta Catenin|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Cell Transformation, Neoplastic|Tumorigenesis|*Colonic Neoplasms|*Neoplastic Processes|Disease Progression|Cell Adhesion Molecules|Hepatocyte 70 HEPACAM 28229220 J. Cancer Res. Clin. Oncol. 2017 10.1007/s00432-016-2333-y 8 5 0 129 *Urinary Bladder Neoplasms|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|*Cell Proliferation|Forkhead Box Protein O3|Forkhead Box Protein O1|Signal Transduction|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Phosphorylation|Chromones|Forkhead Transcription Factors|Membrane Proteins 70 HEPACAM 28093267 Cell. Signal. 2017 10.1016/j.cellsig.2017.01.017 12 13 0 129 Humans|*Carcinoma, Renal Cell|*Interleukin-6|*Up-Regulation|STAT3 protein, human|*STAT3 Transcription Factor|*Cell Proliferation|DNA methyltransferase 3B|*DNA (Cytosine-5-)-Methyltransferases|Kidney Neoplasms|Gene Expression Regulation, Neoplastic|Signal Pathway|DNA Methylation|Cell Line, Tumor|Downregulation|HEPACAM protein, human|Proteins 70 HPS3 28847206 N. Engl. J. Med. 2017 10.1056/NEJMoa1706444 120 1 0 43 Humans|anacetrapib|CETP protein, human|Cholesteryl Ester Transfer Protein|*Oxazolidinones|Hydroxymethylglutaryl-CoA Reductase Inhibitors|*Atherosclerosis|Cholesterol, LDL|Anticholesteremic Agents|Cholesterol, HDL|Triglycerides|Cardiovascular Diseases|Drug Therapy, Combination|Double-Blind Method 51 HPS3 28640947 Pigment Cell Melanoma Res 2017 10.1111/pcmr.12608 2 3 0 43 Humans|*Hermansky Pudlak Syndrome|Dilution, Pigmentary|lysosomal proteins|Proteins|Carrier Proteins|Hypopigmentation|Mutation|Eye|HPS3 protein, human 51 HPS3 28296950 PLoS ONE 2017 PMC5351877 10.1371/journal.pone.0173682 1 0 0 43 Humans|*Hermanski-Pudlak Syndrome|Carrier Proteins|Proteins|Mutation|Lysosome|*B Cells|Organelles|Protein Transport|HPS3 protein, human 51 HPS3 28284561 Blood Cells Mol. Dis. 2017 10.1016/j.bcmd.2017.03.001 0 0 0 43 Male|Humans|*Hermanski-Pudlak Syndrome|*Siblings|Phenotype|Pedigree|Mutation|Sequence Deletion|Homozygote|Genotype|Carrier Proteins|Membrane Proteins|HPS3 protein, human 51 HPS6 29054114 Pigment Cell Melanoma Res 2017 10.1111/pcmr.12662 4 0 0 1552 Humans|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|*Hermanski-Pudlak Syndrome|*Melanosomes|pheomelanin|*Melanins|Japan|Hemorrhagic Disorders|Membrane Proteins|Carrier Proteins|Sequencing, Whole Exome|Mutation|Lysosome 44 HPS6 28976636 Pigment Cell Melanoma Res 2017 10.1111/pcmr.12651 4 0 0 1552 Child|Adult|Humans|Prospective Studies|*Albinism|Albinism, Ocular|Albinism, Oculocutaneous|TYRP1 protein, human|Membrane Glycoproteins|Mutations|Phenotype|Oxidoreductases|Membrane Transport Proteins|Genotypes|Polymerase Chain Reaction|GPR143 protein, human|Eye Proteins 44 HPS6 28640947 Pigment Cell Melanoma Res 2017 10.1111/pcmr.12608 2 3 0 1552 Humans|*Hermansky Pudlak Syndrome|Dilution, Pigmentary|lysosomal proteins|Proteins|Carrier Proteins|Hypopigmentation|Mutation|Eye|HPS3 protein, human 44 HPS6 28296950 PLoS ONE 2017 PMC5351877 10.1371/journal.pone.0173682 1 0 0 1552 Humans|*Hermanski-Pudlak Syndrome|Carrier Proteins|Proteins|Mutation|Lysosome|*B Cells|Organelles|Protein Transport|HPS3 protein, human 44 hydin 29057897 Sci Rep 2017 PMC5651853 10.1038/s41598-017-13947-3 1 2 0 24 Animals|Mice|Rats|*Cilia|*Ependyma|*Cerebral Ventricles|Lateral Ventricles|Hydrocephalus|polycystic kidney disease 2 protein|TRPP Cation Channels|*Cell Movement|Brain|*Alcohol Consumption 49 IFNE 28196779 Dev. Comp. Immunol. 2017 10.1016/j.dci.2017.02.005 8 0 0 58 Animals|*Type I Interferons|*Atlantic Salmon|Infectious salmon anemia virus|Orthomyxoviridae Infections|Antiviral Agents|Fish Diseases|Interferon-beta|*Adaptive Immunity|Adjuvants, Immunologic|Interferon Regulatory Factors 19 IFNK 28324805 Cytokine 2017 10.1016/j.cyto.2017.03.005 0 0 0 71 Humans|*Common Variable Immunodeficiency|interferon kappa|*Interferon Type I|Sequencing, Whole Exome|Mutation|Pedigree|Genotype|Base Sequence 19 IGHMBP2 29272405 Hum. Mol. Genet. 2017 PMC5886155 10.1093/hmg/ddx434 4 0 0 49 Humans|Infant, Newborn|Mice|Animals|Spinal muscular atrophy with respiratory distress 1|*Muscular Atrophy, Spinal|*Respiratory Distress Syndrome, Newborn|Neuromuscular Junction|Motor Neurons|DNA-Binding Proteins|Transcription Factors|Muscle, Skeletal|Disease Models, Animal|Adeno-Associated Virus|IGHMBP2 protein, human 118 IGSF9 28786528 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2017 10.1002/ajmg.b.32577 4 0 0 96 Humans|*Bipolar Disorder|Quality of Life|*Schizophrenia|Multifactorial Inheritance|Genome-Wide Association Study|Depressive Disorder, Major|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Suicidal Ideation|Genetic Loci|Case-Control Studies|*Psychopathology|Suicide|Phenotype|Risk Factors|Antipsychotic Agents|White 19 IGSF9 28465230 Infect. Genet. Evol. 2017 10.1016/j.meegid.2017.04.026 0 0 0 96 Female|Animals|*Bombyx|*Nosema|*Turtles|Insect Proteins|cDNA|Amino Acid Sequence|Cloning, Molecular|Isoforms|Gene Expression Profiling|Larvae|Immunoglobulin|RNA, Messenger|Infections 19 IMPG2 28644393 Genes (Basel) 2017 PMC5541303 10.3390/genes8070170 3 2 0 17 Humans|*Proteoglycans|Vitelliform Macular Dystrophy|*Mutations|*Retina|Eye Proteins|*Extracellular Matrix|Extracellular Matrix Proteins|Pedigree|*Vision Disorders|Tomography, Optical Coherence 26 IRX2 28570300 Pharmacogenet. Genomics 2017 10.1097/FPC.0000000000000286 1 0 0 141 Adult|Child|Humans|*Cytarabine|Prospective Studies|*Leukemia, Myeloid, Acute|Idarubicin|Antimetabolites, Antineoplastic|Single Nucleotide Polymorphisms|Remission Induction|Alleles|Genotype|Antineoplastic Combined Chemotherapy Protocols 71 IRX2 28430825 PLoS Genet. 2017 PMC5419579 10.1371/journal.pgen.1006719 16 1 0 141 Humans|Male|Female|*Genome-Wide Association Study|*Adiposity|*Obesity|Waist to Hip Ratio|*Anthropometry|Body Mass Index|Polymorphism, Single Nucleotide|Transcription Factor 7-Like 2 Protein|Genetic Predisposition to Disease|Genetic Loci|African Continental Ancestry Group|Linkage Disequilibrium|European Continental Ancestry Group|Allele Frequency|Ethnic Groups|HABP2 protein, human|Serine Endopeptidases 71 IRX2 28105936 BMC Genomics 2017 PMC5249001 10.1186/s12864-016-3352-4 9 13 0 141 Humans|*Senescence, Replicative|*Aging|Fibroblasts|Oxidative Stress|Signal Transduction|Cells, Cultured|Stress, Physiological 71 KCNJ13 29187713 J. Vet. Med. Sci. 2017 PMC5836754 10.1292/jvms.17-0528 1 13 0 30 Swine|Animals|Enterotoxigenic Escherichia coli|Escherichia coli Infections|Enterotoxins|Diarrhea|Escherichia coli Proteins|Bacterial Toxins|Swine Diseases|*Colon 40 KCNJ13 29058194 Methods Mol. Biol. 2017 10.1007/978-1-4939-7362-0_16 3 0 0 30 Humans|Kir7.1 channel|MC4R protein, human|*Melanocortin 4 Receptor|*Thallium|*Potassium Channels, Inwardly Rectifying|Potassium Channel Blockers|HEK293 Cells|Neurons 40 KCNJ13 28878288 Sci Rep 2017 PMC5587531 10.1038/s41598-017-11034-1 5 7 0 30 Mice|Animals|Kir7.1 channel|*Potassium Channels, Inwardly Rectifying|*Retina|Electroretinography|Retinal Pigment Epithelium|Retinal Photoreceptors|*Electrophysiological Phenomena|Amino Acid Sequence|Blindness|RNA, Messenger|Mutations|Electrophysiology 40 KCNJ13 28344592 Front Genet 2017 PMC5344932 10.3389/fgene.2017.00028 6 15 0 30 Humans|Mice|Animals|*Dysbindin|*GABAergic Neurons|Dystrophin-Associated Proteins|Synapse|Hippocampus|Neurotransmission|Schizophrenia|Interneurons|Carrier Proteins|Phenotypes 40 KIAA0586 29146704 Clin J Am Soc Nephrol 2017 PMC5718273 10.2215/CJN.05660517 8 0 0 86 Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Prospective Studies|Ciliopathy|*Kidney Disease|Membrane Proteins|Adaptor Proteins, Signal Transducing|Mutation|Pedigree|Heterogeneities, Genetic 27 KIAA0586 28125082 Genet. Med. 2017 10.1038/gim.2016.204 25 1 0 86 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Phenotype|Brain|Membrane Proteins|Mutation|Magnetic Resonance Imaging 27 KLHL7 29074562 J. Med. Genet. 2017 10.1136/jmedgenet-2017-104748 3 0 0 90 Bohring syndrome|Intellectual Disability|Craniosynostoses|Facies|Phenotype|Mutations|Alleles|Repressor Proteins 30 KLHL7 29032201 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.10.049 1 4 0 90 *Retinitis Pigmentosa|*Ubiquitination|*Cell Nucleolus|Genes, Dominant|Mutations|Ubiquitin|Pedigree|Autoantigens 30 KLHL7 28391543 Neurogenetics 2017 PMC5522530 10.1007/s10048-017-0514-8 8 2 0 90 30 LMOD2 29223925 Arch. Biochem. Biophys. 2017 PMC5762396 10.1016/j.abb.2017.12.005 5 3 0 42 *Tropomodulin|*Actins|*Protein Binding|Tropomyosin|Actin Cytoskeleton|Binding Sites|Isoforms|Cytoskeletal Proteins|Mutations 19 LMOD2 29078393 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5692592 10.1073/pnas.1713763114 10 3 0 42 Humans|Mice|Animals|*HSP27 Heat-Shock Proteins|*Filaments, Actin|Sarcomeres|Cardiac Muscle|Tropomodulin|Cardiomyocytes|Muscle Proteins|Cardiomyopathy, Dilated|Mice, Knockout|Heart Failure|Muscle, Skeletal|Actinin|*Organogenesis|HSPB7 protein, human|HSPB7 protein, mouse 19 LMOD2 28834725 Biophys. J. 2017 PMC5567609 10.1016/j.bpj.2017.07.007 3 2 0 42 *Actins|Tropomyosin|Actin Cytoskeleton|Protein Binding|Muscle Proteins|Amino Acid Sequence|Protein Structure, Tertiary|Binding Sites|Sequence Homology, Amino Acid|Protein Domains|Models, Molecular 19 LMOD2 28732641 Arch. Biochem. Biophys. 2017 PMC5568491 10.1016/j.abb.2017.07.006 4 20 0 42 *Tropomyosin|*Actin Filament|Tropomodulin|Actin|*Cardiomyopathy|Familial dilated cardiomyopathy|Cardiomyopathy, Dilated|*Mutation|Protein Binding|Binding Sites|Muscle, Striated|Amino Acid Sequence|Muscle Cells|Cardiac Muscle|Muscular Diseases|Muscle, Skeletal|Circular Dichroism 19 LMOD3 28815944 Am. J. Med. Genet. A 2017 PMC5603416 10.1002/ajmg.a.38383 1 0 0 46 Humans|Female|Pregnancy|Infant, Newborn|Nemaline Myopathy|*Myopathy, Congenital|Myopathies, Structural, Congenital|Muscle Proteins|Pedigree|Homozygote|Muscle, Skeletal|Sequencing, Whole Exome|Phenotype|Hypotonia|Mutation 22 LMOD3 28689068 Stem Cell Res 2017 10.1016/j.scr.2017.06.013 2 1 0 46 Mice|Animals|*Mouse Embryonic Stem Cells|*Culture Media, Conditioned|*Hair Cells, Auditory, Inner|Embryoid Bodies|*Stromal Cell|Embryonic Stem Cells|*Transfection|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Cochlea|Gene Expression Regulation, Developmental 22 LOXHD1 29287594 J Transl Med 2017 PMC5747948 10.1186/s12967-017-1370-x 17 18 0 9 Humans|*Brain Cancer|Receptor, ErbB-2|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Prognosis|Transcriptome 34 LOXHD1 28984810 Otol. Neurotol. 2017 10.1097/MAO.0000000000001571 7 0 0 9 Humans|Czech Republic|*Hearing Loss, Sensorineural|*Deafness|Connexins|Mutations|Hearing Loss|Membrane Proteins|Sequence Deletion|STRC protein, human 34 LOXHD1 28900111 Sci Rep 2017 PMC5595904 10.1038/s41598-017-10099-2 1 0 0 9 Humans|Pilot Projects|*Genes, Recessive|Pedigree|Sequencing, Next-Generation|Deafness|Genetic Association Studies|Heterozygote|Frequencies, Allele|Connexins|Mutation|Genetic Predisposition to Disease|Sequence Analysis, DNA|Asian Continental Ancestry Group|Base Sequence 34 LOXHD1 28235828 G3 (Bethesda) 2017 PMC5386877 10.1534/g3.117.039784 7 6 0 9 Pregnancy|Child|Humans|Female|*Environmental Pollutants|Autism Spectrum Disorder|Halogenated Diphenyl Ethers|Maternal Exposure|Polychlorinated Biphenyls|*Prenatal Care|Fetal Blood|*Fetus 34 LYPLAL1 29129355 Syst. Appl. Microbiol. 2017 10.1016/j.syapm.2017.09.006 4 0 0 45 Humans|*Metagenomes|RNA, Ribosomal, 16S|*Islam|Genome-Wide Association Study|Microbiota, Gut|Metagenomics|Bacteria|DNA, Bacterial|DNA, Ribosomal|Microbiome|Sequence Analysis, DNA|Prevotella|Feces|Bacteroides|Phylogeny|Cluster Analysis|*Asian Continental Ancestry Group 71 LYPLAL1 29084768 Dis Model Mech 2017 PMC5769613 10.1242/dmm.031864 2 3 0 45 Genome-Wide Association Study|Obesity|Diet, High-Fat|Adipose Tissue|Glucose 71 LYPLAL1 28757432 Exp. Hematol. 2017 10.1016/j.exphem.2017.07.007 0 0 0 45 Humans|4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide|*Prediabetic State|Diabetes Mellitus, Type 2|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|*Pyrimidines|Fusion Proteins, bcr-abl|Protein Kinase Inhibitors|Imatinib Mesylate|*Risk Factors|Insulin Resistance 71 LYPLAL1 28645872 Gene 2017 10.1016/j.gene.2017.06.030 0 1 0 45 Adolescent|Child|Humans|Genome-Wide Association Study|*Chinese|*Hypertension|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Childhood Obesity|Case-Control Studies|Risk Factors|ETV5 protein, human|DNA-Binding Proteins|Transcription Factors|LYPLAL1 protein, human|Lysophospholipase 71 LYPLAL1 28594920 PLoS ONE 2017 PMC5464588 10.1371/journal.pone.0178685 4 0 0 45 Humans|Nonalcoholic Fatty Liver Disease|Frequencies, Allele|Single Nucleotide Polymorphisms|Genetic Association Studies|Genetic Predisposition to Disease|Lipase|Allele|Genotype|*Fibrosis|Lysophospholipase|*Anti-Retroviral Agents|Membrane Proteins|Adaptor Proteins, Signal Transducing|Liver|Chondroitin Sulfate Proteoglycans|Triglycerides|Nerve Tissue Proteins|*HIV Seropositivity 71 LYPLAL1 28539126 BMC Med Inform Decis Mak 2017 PMC5444041 10.1186/s12911-017-0454-0 4 9 0 45 Humans|*Alzheimer Disease|*Neuroimaging|*Biomarkers|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Sequencing, Whole Genome|Computational Biology|Endophenotypes|Sequencing, Next-Generation 71 MYNN 28108556 Hum. Mol. Genet. 2017 PMC5731438 10.1093/hmg/ddx026 12 0 0 15 Humans|*Lupus Erythematosus, Systemic|SNPs|Asians|Genetic Predisposition to Disease|Genome-Wide Association Study|Genotype|European Continental Ancestry Group|Gene Expression|Cohort Studies|Hongkong|MYNN protein, human|Kruppel-Like Transcription Factors 19 MYO3A 28642064 J Genet Genomics 2017 10.1016/j.jgg.2017.03.008 9 0 0 81 Humans|Junction Protein, Gap|Connexin 30|Connexin 26|Usher Syndromes|Mutation|Sequencing, Next-Generation|African Continental Ancestry Group|Asian|Nigeria|South Africa 50 MYPN 29050118 Zhonghua Er Ke Za Zhi 2017 10.3760/cma.j.issn.0578-1310.2017.10.014 0 0 0 235 32 MYPN 28515850 World J Cardiol 2017 PMC5411966 10.4330/wjc.v9.i4.320 1 6 0 235 *Gene Regulatory Networks|*Cardiomyopathy, Restrictive|*Sarcomeres|Quantitative Trait Loci|Muscle Proteins|Mutation 32 MYPN 28427417 J Transl Med 2017 PMC5399316 10.1186/s12967-017-1180-1 7 1 0 235 Humans|Short Qt Syndrome|*Arrhythmias, Cardiac|*Cardiomyopathy, Hypertrophic|Electrocardiography|Pedigree|Calcium Channels, L-Type|Genetic Predisposition to Disease|Mutation|Phenotype|Chinese|CACNA1C protein, human|MYPN protein, human|Muscle Proteins 32 MYPN 28220527 Ann. Neurol. 2017 10.1002/ana.24900 9 0 0 235 Cap Myopathy|*Myopathies, Structural, Congenital|Myopathies, Nemaline|*Mutations|Homozygote|Muscle Proteins|Pedigree|Muscle, Skeletal|Phenotypes|Cardiomyopathies 32 MYPN 28115213 Appetite 2017 10.1016/j.appet.2017.01.004 4 0 0 235 Adult|Humans|Newfoundland and Labrador|SNPs|*Behavior, Addictive|Genetic Predisposition to Disease|Genotype|Gene Frequency|Allele|Obesity|Receptors, Dopamine D2|*Food|Food Addiction|Canada|ERAP1 protein, human|Aminopeptidases|Minor Histocompatibility Antigens 32 MYPN 28064046 Meat Sci. 2017 10.1016/j.meatsci.2016.11.018 1 0 0 235 Swine|Animals|*Polymorphism, Single Nucleotide|*Red Meat|*Pork Meat|Italy|Meat|*Phenotype|Sus scrofa|Gene Frequency|Genetic Association Studies|Breeding 32 OPA3 28969390 Brain 2017 10.1093/brain/awx219 22 0 0 152 Humans|Animals|Mice|Infant|*Optic Atrophy, Autosomal Dominant|*Mitochondrial Dynamics|GTPase|*Mutations|Mitochondrial Proteins|Mitochondria|Microtubule-Associated Proteins|Exome|Optic Nerves|Peroxisomes|DNM1L protein, human|OPA1 protein, human 76 OPA3 28848318 Mol. Vis. 2017 PMC5561143 3 0 0 152 Humans|*Genetic Testing|Optic Atrophy, Autosomal Dominant|*Optic Neuropathy|*Optic Nerve|Mutations|GTP Phosphohydrolases|DNA, Mitochondrial|Asian Continental Ancestry Group|*Rare Diseases|Polymerase Chain Reaction 76 OPA3 28698153 Food Chem. Toxicol. 2017 10.1016/j.fct.2017.07.018 0 12 0 152 *Cisplatin|*Curcumin|*Mitochondria|*Bioenergetics|Oxidative Stress|Acute Kidney Injury|Antineoplastic Agents|turmeric extract|Curcuma longa|Apoptosis|Kidney|Plant Extracts 76 OPA3 28652416 In Vivo 2017 PMC5566899 10.21873/invivo.11090 0 0 0 152 Humans|*Mitochondrial Dynamics|*Mitochondrial Membranes|Leber Hereditary Optic Neuropathy|*Optic Neuropathies|Optic Atrophy, Autosomal Dominant|Mitochondrial Diseases|Retinal Ganglion Cells|Mitochondria|DNA, Mitochondrial|Optic Atrophy|GTP Phosphohydrolases|Nerve, Optic|Retina|Mutations|Phenotypes 76 OPA3 28569192 BMC Genomics 2017 PMC5452331 10.1186/s12864-017-3811-6 2 0 0 152 Humans|*mRNA|*Binding Sites|3' Untranslated Regions|miRNA 76 OPA3 28081242 PLoS ONE 2017 PMC5230780 10.1371/journal.pone.0170090 0 1 0 152 Humans|Child|Child, Preschool|*Leber Hereditary Optic Neuropathy|*Optic Atrophy, Dominant|*Chinese|DNA, Mitochondrial|DNA Mutational Analysis|Mutation|Pedigree|GTP Phosphohydrolases|*Optic Nerve Diseases|Mitochondria 76 OPA3 28050599 Cold Spring Harb Mol Case Stud 2017 PMC5171695 10.1101/mcs.a001156 3 0 0 152 Female|Humans|*Optic Atrophy|Optic Atrophy, Autosomal Dominant|*Cataracts|Exome|Pedigree|*Lipodystrophy|GTP Phosphohydrolases|*Peripheral Neuropathy|Mutation 76 PCDH12 29064472 Transl Psychiatry 2017 PMC5682604 10.1038/tp.2017.210 4 2 0 30 *Pursuit, Smooth|*Eye Movements|*Genome-Wide Association Study|*Psychotic Disorders|*Schizophrenia|Bipolar Disorder|*Phenotypes|Inhibition, Psychological|Saccades|Family|Single Nucleotide Polymorphism 27 PCDH12 28804758 Neurol Genet 2017 PMC5530423 10.1212/NXG.0000000000000166 1 0 0 30 Humans|*Brain Diseases|*Nervous System Malformations|Sodium-Phosphate Cotransporter Proteins, Type III|*Calcinosis|Pedigree|Brain|Phenotype|Mutation|PCDH12 protein, human|Cadherins 27 PDE6H 29259520 Yale J Biol Med 2017 PMC5733843 5 2 0 11 Animals|Achromatopsia 1|*Color Vision Defects|*Gene Therapy|Dependovirus|Photoreceptor, Cone|Cyclic Nucleotide-Gated Cation Channels|Genetic Vectors|Electroretinography|Retina|Disease Models, Animal|Mutation 27 PDE6H 29257187 J Pediatr Ophthalmol Strabismus 2017 10.3928/01913913-20171117-01 0 0 0 11 Humans|Achromatopsia 1|*Color Vision Defects|Retinal Cone Photoreceptor Cells|Color Vision|Electroretinography|Retinal Disease|Cyclic Nucleotide-Gated Cation Channels|Coherence Tomography, Optical|Fundus Oculi|Photophobia|Visual Acuity|Retina|Mutations|Eye Proteins|Phenotype 27 PDE6H 28795510 Hum. Mutat. 2017 10.1002/humu.23311 10 0 0 11 Humans|Achromatopsia 1|*Color Vision Defects|*DNA Copy Number Variations|Comparative Genomic Hybridization|Gated Channel, Cyclic-Nucleotide|*Mutation|Photoreceptors, Cone|DNA Mutational Analysis|Electroretinography|Pedigree|Phenotype|Homozygote|Photophobia|Exons|Mutation, Missense|Allele|CNGB3 protein, human 27 pdlim3 28454334 Oncol Lett 2017 PMC5403203 10.3892/ol.2017.5612 5 0 0 60 Humans|Female|*Docetaxel|*Interleukin-8|*Cancer-Associated Fibroblasts|Carcinoma, Ductal, Breast|Fibroblasts|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Adhesion|Cell Transformation, Neoplastic|Profile, Gene Expression|Breast Cancer 35 PEPD 29233996 Nat Commun 2017 PMC5727116 10.1038/s41467-017-02097-9 1 71 0 553 TP53 protein, human|*Tumor Suppressor Protein p53|proline dipeptidase|Proto-Oncogene Proteins c-mdm2|*Dipeptidases|Cell Nucleus|bcl-2-Associated X Protein|Apoptosis|Cytoplasm|Phosphorylation|Mitochondria|Cell Line, Tumor|Cell Survival|Oxidative Stress|Cell Death|Protein Binding 172 PLCL2 28360101 J. Biol. Chem. 2017 PMC5437242 10.1074/jbc.M116.759928 0 0 0 21 Female|*Phospholipase C|Ovarian Follicle|Ovulation|Receptors, LH|Ovary|Luteinizing Hormone|Receptors, FSH|Granulosa Cells|Oocytes 19 PLCL2 28341745 J. Biol. Chem. 2017 PMC5427276 10.1074/jbc.M117.784777 3 2 0 21 Mice|Animals|*Calcineurin|*Osteoclasts|*Phospholipase C|Transcription Factor, NFATC1|*Calcium Signaling|Osteoclastogenesis|RANK Ligand|CSF1 protein, human|M-CSF|Bone Resorption|Cell Differentiation|*Up-Regulation|Bone Marrow Cells|*Calcium, Dietary|Bone and Bones|*Transcriptional Activation|Phosphorylation|Mice, Knockout 19 POU5F1B 28463958 Br. J. Cancer 2017 PMC5520085 10.1038/bjc.2017.104 2 8 0 44 Humans|Male|*DNA Methylation|*Prospective Studies|Genetic Susceptibility|Polymorphism, Single Nucleotide|Prostate Cancer|Genotype|Case-Control Studies|Risk Factors|*Chromosome Structures 19 PRCD 28855430 J. Vet. Med. Sci. 2017 PMC5658571 10.1292/jvms.17-0243 3 0 0 11 Dogs|Animals|Japan|*Cone-Rod Degeneration|*Gene Frequency|*Cone Dystrophy|Retinal Degeneration|Polymerase Chain Reaction|Pedigree|Breeding|Chromosome Mapping|Restriction Fragment Length Polymorphism|Genotype|Mutation|Allele|Dog Diseases 66 PRDM12 28982197 PLoS ONE 2017 PMC5628920 10.1371/journal.pone.0185985 21 4 0 32 Mice|Animals|*Capsaicin|Ganglia, Nodose|*Vagus Nerve|C Fiber|TRPV Cation Channels|Sensory Neurons|*Sequencing, RNA|Inflammation Mediators|TRPV1 protein, mouse 32 PRDM12 28850031 Elife 2017 PMC5576485 10.7554/eLife.25787 5 49 0 32 Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|Homeodomain Proteins|Neural Tube|Oligodendrocyte Transcription Factor 2|Spinal Cord|Cell Differentiation|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Interneurons|Motor Neurons|Embryo, Mammalian 32 PRDM12 28807049 J Med Case Rep 2017 PMC5556355 10.1186/s13256-017-1387-z 0 0 0 32 Male|Humans|Hereditary Sensory and Autonomic Neuropathy Type I|Pain Insensitivity, Congenital|*Mutation|*Homozygote|Self Mutilation|Sensory Receptor Cells|Prdm12 protein, human|Carrier Proteins|Nerve Tissue Proteins 32 PRDM12 28625870 Dev. Biol. 2017 10.1016/j.ydbio.2017.06.014 0 3 0 32 PAX7 protein, human|*PAX7 Transcription Factor|*Interneurons|Paired Box Transcription Factors|Homeodomain Proteins|PAX3 Transcription Factor|Gene Expression Regulation, Developmental|Spinal Cord|Motor Neurons|Nerve Tissue Proteins|Neural Tube|Progenitor Cells 32 RNASEH2A 29239743 Pediatr. Neurol. 2017 10.1016/j.pediatrneurol.2017.09.002 2 0 0 81 Humans|Child|Autoimmune Diseases of the Nervous System|Nervous System Malformations|*Aicardi Syndrome|Phenotype|Neurological Disorder|Mutations 41 RNASEH2A 28475458 J. Interferon Cytokine Res. 2017 PMC5439407 10.1089/jir.2017.0004 3 1 0 81 Humans|Male|Child|Female|Singleton Merten syndrome|*Odontodysplasia|*Metacarpus|*Vascular Calcification|*Muscular Diseases|*Aortic Diseases|*Osteoporosis|*Dental Enamel Hypoplasia|Interferon-Induced Helicase, IFIH1|Nervous System Malformations|Mutation|Phenotype|Bone and Bones|Mutation, Missense 41 RNASEH2A 28387595 J. Interferon Cytokine Res. 2017 10.1089/jir.2016.0117 1 3 0 81 Humans|Nervous System Malformations|Autoimmune Diseases of the Nervous System|*Aicardi Syndrome|SAM Domain and HD Domain-Containing Protein 1|Ribonuclease H|Mutation|Adenosine Deaminase|*Biomarkers|Brain|Exodeoxyribonucleases|Imaging, Magnetic Resonance|Interferon|*Gene Expression|Phosphoproteins 41 s100a5 29240404 Biochemistry 2017 PMC5995566 10.1021/acs.biochem.7b01086 0 3 0 15 Humans|S100A6 Protein|S100 Proteins|Protein Binding|Protein Conformation|Amino Acid Sequence|Cell Cycle Proteins|Binding Sites|Peptides|Models, Molecular|Calorimetry|S100A5 protein, human 39 s100a5 29201357 BMC Biophys 2017 PMC5700546 10.1186/s13628-017-0040-y 2 8 0 15 Humans|Protein Binding|Binding Sites|S100 Proteins|Calorimetry|Copper|Circular Dichroism|Signal Transduction|S100A5 protein, human 39 Six5 29257230 Mol Med Rep 2017 10.3892/mmr.2017.8196 0 0 0 112 Humans|Branchiootic syndrome|*Whole Exome Sequencing|Esophageal atresia with or without tracheoesophageal fistula|*Esophageal Atresia|Hedgehog Proteins|*Branchio-Oto-Renal Syndrome|*Mutation|Protein Tyrosine Phosphatases|Intracellular Signaling Peptides and Proteins|Nuclear Proteins|Pedigree|Homeodomain Proteins|*Heredity|Ear|*Databases, Genetic|Tracheoesophageal Fistula|GLI3 protein, human|Zinc Finger Protein Gli3 113 Six5 29100090 Am. J. Hum. Genet. 2017 PMC5673636 10.1016/j.ajhg.2017.09.018 11 1 0 112 Humans|Mice|Child|Animals|*Exome|Renal Adysplasia|*Urogenital Abnormalities|Hereditary renal agenesis|*Kidney Diseases|*Kidney|*Urinary Tract|*Mutations|Phenotypes|Sequencing, Whole Exome|Homozygote|Pedigree|Vesico-Ureteral Reflux|Membrane Proteins|Zebrafish|Slit3 protein, mouse 113 Six5 28618409 Am. J. Nephrol. 2017 10.1159/000477590 1 0 0 112 Humans|*Solitary Kidney|Branchio-Oto-Renal Syndrome|*Asian Continental Ancestry Group|Mutations|Hepatocyte Nuclear Factor 1-beta|Homeodomain Proteins|Nuclear Proteins|Intracellular Signaling Peptides and Proteins|Genetic Predisposition to Disease|Phenotype|Cohort Studies 113 Six5 28583505 Int. J. Pediatr. Otorhinolaryngol. 2017 PMC5516569 10.1016/j.ijporl.2017.04.037 0 0 0 112 *Branchio-Oto-Renal Syndrome|Protein Tyrosine Phosphatases|Intracellular Signaling Peptides and Proteins|Nuclear Proteins|Genetic Testing|Mutations|Pedigree|Homeodomain Proteins|Hearing Impairment|Renal Adysplasia|Kidney 113 Six5 28257691 Am. J. Hum. Genet. 2017 PMC5339342 10.1016/j.ajhg.2017.01.033 17 3 0 112 Humans|*Myotonic Dystrophy|*Methylation|Myotonin-Protein Kinase|Trinucleotide Repeat Expansion|Polymerase Chain Reaction 113 Six5 28211918 Sci Rep 2017 PMC5304155 10.1038/srep42522 8 1 0 112 Humans|*Myotonic Dystrophy|Myotonin-Protein Kinase|*Induced Pluripotent Stem Cells|Trinucleotide Repeat Expansion|Cell Lines|Cell Differentiation|Cardiomyocytes 113 slamf8 28067908 Nat. Genet. 2017 PMC5289481 10.1038/ng.3760 130 1 0 45 Humans|*Genome-Wide Association Study|*Inflammatory Bowel Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Quantitative Trait Loci|Allele|*Integrins|Inflammation 19 SMPX 29287879 Int. J. Pediatr. Otorhinolaryngol. 2017 10.1016/j.ijporl.2017.10.040 1 0 0 17 Nonsyndromic Deafness|*Deafness|*Hearing Loss|Hearing Loss, Sensorineural|*RNA Splicing|Genes, X-Linked|Pedigree|Genetic Diseases, X-Linked|Whole Exome Sequencing|Muscle Proteins|Mutation 41 SMPX 28684431 J. Exp. Med. 2017 PMC5551580 10.1084/jem.20170724 9 30 0 17 *Cancer-Associated Fibroblasts|*Chromatin|Signal Transduction|Cancer, Skin|Activating Transcription Factor 3|Cell Line, Tumor|Fibroblasts|Cell Transformation, Neoplastic 41 SMPX 28542515 PLoS ONE 2017 PMC5444825 10.1371/journal.pone.0178384 5 0 0 17 Humans|Nonsyndromic Deafness|*Frameshift Mutation|*Deafness|Hearing Loss, Sensorineural|*Genes, X-Linked|*Chinese|Hearing Loss|Pedigree|Genetic Diseases, X-Linked|Sequencing, Whole Exome|Mutation|Exons|Introns|Sequence Analysis|Muscle Proteins|SMPX protein, human 41 SMPX 28271491 Histol. Histopathol. 2017 10.14670/HH-11-886 0 0 0 17 Humans|Mice|Animals|*Organogenesis|myogenic factor 6|Myogenic Regulatory Factors|*Muscle, Skeletal|Ear, Inner|Hair Cells, Auditory, Inner|Gene Expression Regulation, Developmental|Cell Differentiation|SMPX protein, human|Muscle Proteins 41 SNX14 29112993 Neuropediatrics 2017 10.1055/s-0037-1608652 4 0 0 37 Humans|Child|*Neurologists|*Autophagy|Lysosomes|Phenotype|Mutation 22 SPATA5 28293831 Adv. Exp. Med. Biol. 2017 10.1007/5584_2016_206 2 0 0 119 Female|*Hearing Impairment|*Mutations|Hearing Loss, Sensorineural|Epilepsy|Mental Retardation|Exome|Deafness|Pedigree|Membrane Proteins 19 TANGO2 28934986 Genome Med 2017 PMC5607840 10.1186/s13073-017-0472-7 18 0 0 104 *DNA Copy Number Variations|*Exons|Genotype-Phenotype Correlations|Polymorphism, Single Nucleotide 23 TANGO2 28327206 Genome Med 2017 PMC5361813 10.1186/s13073-017-0412-6 59 5 0 104 *Exome|High-Throughput Nucleotide Sequencing|Sequence Analysis, DNA|DNA Copy Number Variations|Computational Biology|Mutation 23 taok2 29241837 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.12.006 0 0 0 143 Neurons|Synapses|Parkinson Disease|Signal Transduction|Neurodegenerative Diseases|Protein-Serine-Threonine Kinases|Phosphorylation 19 taok2 28830982 Mol. Cancer Ther. 2017 10.1158/1535-7163.MCT-17-0077 0 2 0 143 *Centrosome|*Mitosis|Spindle Apparatus|*Cell Death|Protein-Serine-Threonine Kinases|Cell Line, Tumor|Cell Proliferation|Apoptosis 19 taok2 28386116 Sci Rep 2017 PMC5429658 10.1038/s41598-017-00739-y 8 3 0 143 Humans|*Cancer|*G-Quadruplexes|5'UTRs|RNA Sequence|*Mutations|Protein Biosynthesis|mRNA|Thermodynamic|Guanine|*Biochemical Phenomena|Gene Expression Regulation 19 taok2 28385331 J. Dermatol. Sci. 2017 10.1016/j.jdermsci.2017.03.018 0 0 0 143 Humans|*Homozygote|*Mutation|Immunologic Deficiency Syndromes|Warts|Pedigree|Phenotype|Human Papillomavirus Infection|Infections, Viral|T-Lymphocytes 19 taok2 28065648 Neuron 2017 PMC5267388 10.1016/j.neuron.2016.12.006 26 33 0 143 *Dendritic Spines|*Phosphorylation|DNA Copy Number Variations|*PSD95 Protein|Synapses|Receptors, N-Methyl-D-Aspartate|Intracellular Signaling Peptides and Proteins|Serine Threonine Kinase|Neurons|Hippocampus|Membrane Proteins|Signal Transduction 19 TGM6 29062094 Sci Rep 2017 PMC5653837 10.1038/s41598-017-14254-7 9 6 0 55 Humans|Episodic Ataxia|Republic of Korea|*Ataxia, Truncal|Mutations|Phenotype|Pedigree|Cerebellar Ataxia|Sequencing, Whole Exome|Excitatory Amino Acid Transporter 1|Genetic Heterogeneity|Calcium Channels|Seizures|UBR4 protein, human|Calmodulin-Binding Proteins|Cytoskeletal Proteins 22 TGM6 28934387 Hum. Mol. Genet. 2017 10.1093/hmg/ddx259 5 2 0 55 Humans|Animals|Drosophila melanogaster|*Unfolded Protein Response|*Spinocerebellar Ataxias|*Mutations|Endoplasmic Reticulum Stress|Transglutaminases|Mutation, Missense|Neurons 22 TGM6 28273770 Mult. Scler. 2017 10.1177/1352458516684022 3 0 0 55 Animals|*Multiple Sclerosis|*Astrocytes|Multiple Sclerosis, Chronic Progressive|Multiple Sclerosis, Relapsing-Remitting|*Autoantigens|*Upregulation|Encephalomyelitis, Autoimmune, Experimental|*Central Nervous System|*Transcriptional Activation|Neurons|Transglutaminases 22 TSPEAR 28634816 Cancer Immunol. Immunother. 2017 PMC5647210 10.1007/s00262-017-2032-9 5 2 0 2 Humans|*T-Cell Receptor Gene|T Cell Receptor|T-Lymphocytes|Lymphocyte Activation|Hepatitis C virus|Immunotherapies|Protein Binding|Peptides|Hepatitis C|Antigen|Cross Reactions 19 UNC13A 29141910 J. Biol. Chem. 2017 PMC5766930 10.1074/jbc.M117.816884 11 0 0 276 Animals|*Mast Cells|UNC13B protein, human|*Nerve Tissue Proteins|Cell Degranulation|TYRP1 protein, human|*Membrane Glycoproteins|*Cell Count|Membrane Proteins 88 USB1 29231270 J. Cell. Biochem. 2017 10.1002/jcb.26547 3 4 0 66 *A549 Cells|Carcinoma, Non-Small-Cell Lung|*Butyric Acid|Lung Cancer|MIRN574 microRNA, human|*MicroRNAs|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|3' Untranslated Regions|mRNA|Downregulation|Cell Proliferation|Cell Movement|Cell Line, Tumor|Up-Regulation|Apoptosis 34 USB1 28887445 Nat Commun 2017 PMC5591277 10.1038/s41467-017-00484-w 8 22 0 66 Humans|*Spliceosomes|*Ribonucleoprotein, U4-U6 Small Nuclear|U6 small nuclear RNA|snRNA|Ribonucleoprotein, Small Nuclear|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|RNA Splicing|Nucleic Acid Conformation|Protein Binding|Models, Molecular|RNA-Binding Proteins|Phosphoric Diester Hydrolases|USB1 protein, human|Prp24 protein, S cerevisiae 34 USB1 28353165 J. Clin. Immunol. 2017 10.1007/s10875-017-0385-7 0 0 0 66 Poikiloderma with Neutropenia|Morocco|*Skin Abnormalities|*Neutropenia|Phenotype|Mutation|Phosphoric Diester Hydrolases 34 USP9Y 28853286 J. Proteome Res. 2017 10.1021/acs.jproteome.7b00391 6 0 0 19 Humans|Male|Female|Chromosomes, Human, Y|TYRP1 protein, human|*Membrane Glycoproteins|*Organogenesis|*Cell Differentiation|Sex Chromosomes|Transducin|TBL1Y protein, human|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 80 USP9Y 28732082 PLoS ONE 2017 PMC5521774 10.1371/journal.pone.0181204 3 0 0 19 Child|Humans|Prospective Studies|*Osteosarcoma|*Sarcoma|*Genomics|*Databases, Factual|*Soft Tissue Neoplasms|Bioinformatics|Tissue Banks|*In Silico|Biomarkers, Tumor|Researchers|*Data Management|Ohio 80 USP9Y 28600258 IEEE/ACM Trans Comput Biol Bioinform 2017 PMC5986621 10.1109/TCBB.2017.2712607 0 5 0 19 Cancer|*Clustering|*Algorithm|Computational Biology|Gene Expression Profiling|Gene Expression Profiles|*Biochemical Phenomena 80 USP9Y 28244125 Anim. Genet. 2017 10.1111/age.12549 2 0 0 19 Male|Cattle|Animals|*Y Chromosome|Breeding|Haplotypes|Microsatellites|Genotype|Genetic Variation|SNPs|Phylogeny|INDEL Mutation|Europe|Spain|Africa 80 VPS13C 29175050 Mol Metab 2017 PMC5784322 10.1016/j.molmet.2017.10.014 3 22 0 72 Animals|Mice|*Lipolysis|*Adipocytes, Brown|*Lipid Droplet|Carbon-13|*Carbon Isotopes|Proteomics|Adipose Tissue, Brown|*Proteins|Thermogenesis|Adipose Tissue, White|*Protein Transport|Energy Metabolism|Lipase|Acids, Fatty|Proteins, Lipid Droplet 43 VPS13C 28862745 Clin. Genet. 2017 10.1111/cge.13124 12 0 0 72 Humans|Adult|*Parkinson Disease|*Whole Exome Sequencing|*Exome|*Autosomal Recessive Parkinsonism|Genetic Predisposition to Disease|Genetic Testing|Mutation|VPS13C protein, human|Proteins 43 VPS13C 28733970 Curr Neurol Neurosci Rep 2017 PMC5522513 10.1007/s11910-017-0780-8 7 2 0 72 *Parkinson Disease|*Parkinsonism|Mutations|Genetic Predisposition to Disease|Ubiquitin-Protein Ligases 43 VPS13C 28490609 Diabetes 2017 PMC5521867 10.2337/db16-1452 23 4 0 72 Humans|*Insulin Secretion|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Intravenous Glucose Tolerance Test|Blood Glucose|Insulin|Insulin-Secreting Cells|Transcription Factor 7-Like 2 Protein|Genotype|Genetic Predisposition to Disease|Alleles|Polymorphism, Single Nucleotide|Glucose|Genetic Variation|KCNQ1 Potassium Channel 43 WDR11 29263200 EMBO Rep. 2017 PMC5797970 10.15252/embr.201744632 4 26 0 50 Humans|Mice|Animals|*Kallmann Syndrome|*Hedgehog Proteins|Hypogonadism|*Ciliopathy|Receptor, Fibroblast Growth Factor, Type 1|Phenotype|Nerve Tissue Proteins|Mutation|Extracellular Matrix Proteins|WDR11 protein, human|Membrane Proteins|Proto-Oncogene Proteins 36 WDR11 29029386 Oncotarget 2017 PMC5630286 10.18632/oncotarget.19642 1 2 0 50 Humans|Animals|Mice|*Medulloblastoma|*Exome|Hedgehog Proteins|Cerebellar Neoplasms|Gene Expression Profiling|Signal Transduction|*Genetic Testing|*Genes, Tumor Suppressor|WDR11 protein, human|Membrane Proteins|Proto-Oncogene Proteins 36 WDR11 28453858 J. Clin. Endocrinol. Metab. 2017 PMC5505202 10.1210/jc.2017-00332 3 1 0 50 *Pituitary Diseases|Gland, Pituitary|Hypopituitarism|*Mutations|*Multifactorial Inheritance|*Syndrome 36 WDR11 28334899 Hum. Mol. Genet. 2017 PMC6075203 10.1093/hmg/ddx062 40 0 0 50 Humans|Genome-Wide Association Study|*Cholesterol|*Asian|High Density Lipoprotein Cholesterol|Triglycerides|Low Density Lipoprotein Cholesterol|Frequencies, Allele|Linkage Disequilibrium|European Continental Ancestry Group|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Lipids|Genotype|Phenotype|China|Japan|Philippines|Taiwan 36 WDR11 28209183 Hum. Genomics 2017 PMC5314676 10.1186/s40246-017-0098-2 1 7 0 50 Male|Humans|Female|Indonesia|*Hypogonadism|Kallmann Syndrome|Receptors, Peptide|Gastrointestinal Hormones|Receptor, Fibroblast Growth Factor, Type 1|*Boys|Phenotypes|Receptors, G-Protein-Coupled|Neuropeptides|*Virilism|Cryptorchidism|Gonadotropin Releasing Hormone|*Cohort Studies|DNA Helicases|Nerve Tissue Proteins|Penis agenesis|Genital Diseases, Male 36 5HT1 27086724 Eur. J. Neurosci. 2016 10.1111/ejn.13259 1 0 0 0 Animals|*Astacoidea|Octopamine|Social Dominance|Agonistic Behavior|Aggression|Behavior, Animal|*Signal Transduction|*Gonadal Hormones|norsynephrine receptor|Adenylyl Cyclase Inhibitors 176 APMAP 26767403 J. Proteome Res. 2016 10.1021/acs.jproteome.5b01030 5 2 0 44 Pregnancy|Animals|Mice|Female|*Diabetes, Gestational|*Proteomics|Diabetes Mellitus, Type 2|*Adipocyte|*Adipose Tissue|Insulin Resistance|3T3-L1|Insulin|Omentum|Glucose|Signal Transduction|*Membrane Proteins 19 atad5 27045477 Cancer Lett. 2016 10.1016/j.canlet.2016.03.048 6 2 0 147 Humans|Female|*Carcinoma, Ovarian Epithelial|Genome-Wide Association Study|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|Mutations, Germline|Genetic Susceptibility|Cystadenocarcinoma, Serous|Genetic Testing|Sequencing, Next-Generation|Mutation, Missense|DNA-Binding Proteins|Triple-Negative Breast Cancer|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities 35 atad5 26722215 Int. J. Biol. Sci. 2016 PMC4679396 10.7150/ijbs.12310 2 6 1 147 Humans|*Carcinoma, Hepatocellular|hepatitis B virus X protein|*Liver Neoplasms|*Trans-Activators|*Upregulation|B virus, Hepatitis|*Transcriptional Activation|Promoter Regions, Genetic|Hep G2 Cells|DNA Methylation|Gene Expression Regulation, Neoplastic|Chromatin Immunoprecipitation|Cell Line, Tumor|E2F1 protein, human|E2F1 Transcription Factor|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities|DNA-Binding Proteins 35 C12orf65 27858754 J Neuromuscul Dis 2016 PMC5240610 10.3233/JND-150121 2 3 1 45 Humans|Adult|Necrotizing Encephalomyelopathy, Subacute, of Leigh, Adult|*Leigh Disease|*Disease, Mitochondrial|*Optic Atrophies, Hereditary|Mitochondrial Proteins|Optic Atrophy|Mutations|Mitochondria|Pedigree|Phenotype|Peptide Termination Factors|*Intensive Care|C12orf65 protein, human 26 CADPS2 26880577 J. Exp. Med. 2016 PMC4813668 10.1084/jem.20150806 31 11 1 67 Mice|Animals|*Hematopoietic Stem Cell|Cell Movement|Hematopoietic Stem Cell Transplantation|Cell Proliferation|Cells, Cultured|NBEA protein, human|Nerve Tissue Proteins|Mice, Inbred C57BL 37 CADPS2 26743714 Nat Commun 2016 PMC4729875 10.1038/ncomms10286 43 2 7 67 Humans|*hiPSC|*Long Interspersed Nucleotide Elements|Retrotransposons|Alu Elements|Embryonic Stem Cells|HeLa Cells|Minisatellite Repeats|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins 37 CDKN2AIP 27829235 Oncotarget 2016 PMC5348329 10.18632/oncotarget.13138 3 32 0 154 Humans|Mice|Animals|*Carcinoma, Hepatocellular|CTNNB1 protein, human|*beta Catenin|*Liver Neoplasms|*Signal Transduction|TCF Transcription Factors|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Proliferation|Hep G2 Cells|Transcription Factors|Cell Line, Tumor|Up-Regulation 19 CDKN2AIP 27457128 Sci Rep 2016 PMC4960484 10.1038/srep30185 4 27 1 154 Humans|*miRNAs|Azacitidine|Decitabine|Apoptosis Regulatory Proteins|Cellular Senescence|Tumor Suppressor Protein p53|Cell Line, Tumor|RNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|Upregulation|Apoptosis|*Genes, Tumor Suppressor|Cyclin-Dependent Kinase Inhibitor p16|DNA Damage|Signal Transduction|MIRN335 microRNA, human 19 CEP120 27208211 J. Med. Genet. 2016 PMC5013089 10.1136/jmedgenet-2016-103832 17 3 1 226 Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Ciliopathy|*Phenotypes|*Mutations|Orofaciodigital Syndromes|Exome|Pedigree|Sequence Analysis, DNA 22 CEP120 26785701 Sci Rep 2016 PMC4726286 10.1038/srep17958 15 8 1 226 Humans|*Waist-Hip Ratio|*Waist Circumference|*Genome-Wide Association Study|*Asians|Body Mass Index|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Obesity|Genetic Loci|Abdominal Obesity|Genes, MHC Class II|EFEMP1 protein, human|Extracellular Matrix Proteins|CNPY2 protein, human|Adaptor Proteins, Signal Transducing|TSC22D2 protein, human|Carrier Proteins 22 CERKL 27898983 Invest. Ophthalmol. Vis. Sci. 2016 PMC5132076 10.1167/iovs.16-19785 4 0 0 65 Humans|*Whole Exome Sequencing|Exome|*Retina|Retinal Dystrophies|DNA Mutational Analysis|Pedigree|Mutation|Eye Proteins|Sequence Analysis, DNA|Phenotype 57 DDRGK1 27152292 J Nephropathol 2016 PMC4844911 10.15171/jnp.2016.13 0 0 1 145 Humans|Acute Kidney Injury|*Intensive Care|Creatinine|Intensive Care Units|*Epithelial Cell|Infections 19 DISP1 27363716 Hum. Mutat. 2016 10.1002/humu.23038 20 0 0 24 Humans|*Holoprosencephaly|*Mutations|Hedgehog Proteins|*Fibroblast Growth Factor|*Signal Transduction|Eye Proteins|Homeodomain Proteins|Transcription Factors|Nuclear Proteins|Nerve Tissue Proteins|Repressor Proteins|Phenotype|Prosencephalon|Genetic Counseling|Cohort Studies 34 DISP1 26748417 Clin. Genet. 2016 10.1111/cge.12722 7 0 0 24 Humans|Female|Child|Holoprosencephaly 9|*Holoprosencephaly|*Whole Exome Sequencing|Mutation|Heterozygote|Hedgehog Proteins|Pedigree|Phenotype|Genetic Counseling|Prosencephalon|Hypopituitarism|High-Throughput Nucleotide Sequencing|*Heredity|Fingers|Pituitary Gland, Anterior|Polydactyly 34 DNAI2 27823762 Tissue Cell 2016 10.1016/j.tice.2016.10.003 0 0 0 30 Humans|Female|Animals|Mice|*Axonemal Dyneins|*Cilia|*Mice, Inbred NOD|Axoneme|*Fallopian Tubes|*Oviducts|Proteins|Microscopy, Electron|Diabetes Mellitus 30 DRC1 26843384 J. Neurovirol. 2016 PMC4972699 10.1007/s13365-016-0424-9 15 8 1 38 Humans|Animals|Rats|*Rats, Transgenic|*HIV-1|Proteomics|AIDS Dementia Complex|Mitochondria|Neurons|Protein, Mitochondrial|HIV Infections|Brain|Disease Models, Animal|*HIV Seropositivity 45 FAM111A 27480553 Zhonghua Nei Ke Za Zhi 2016 10.3760/cma.j.issn.0578-1426.2016.08.007 0 0 0 19 Adult|Humans|*Hypoparathyroidism, Idiopathic|*Next Generation Sequencing|*Chinese|DNA Mutational Analysis|Parathyroid Hormone|*Genomics|Receptors, Calcium-Sensing|Mutation|Pedigree 19 FAM111A 27234911 Pediatr. Nephrol. 2016 PMC5440500 10.1007/s00467-016-3416-3 20 5 1 19 *Magnesium|Nephrocalcinosis|Renal Tubular Transport, Inborn Errors|Hypercalciuria|Magnesium Deficiency|Claudins|Phenotype|Genetic Predisposition to Disease 19 FAT2 27942226 Onco Targets Ther 2016 PMC5138043 10.2147/OTT.S111176 7 14 0 52 Animals|*Cadherins|Cell Polarity|Morphogenesis|Signal Transduction|*Disease Progression 58 frem1 27736906 PLoS ONE 2016 PMC5063463 10.1371/journal.pone.0163860 1 8 1 54 Mice|Animals|HIV-Associated Nephropathy|Mice, Congenic|Mice, Transgenic|Chromosome Mapping|Alleles|Kidneys|Chromosome|Genetic Predisposition to Disease|HIV-1|*Animals, Laboratory 58 frem1 27648443 Biomed Res Int 2016 PMC5018317 10.1155/2016/1648030 1 5 1 54 Humans|Swine|Animals|*Hepatitis E virus|*Hep G2 Cells|Hepatitis E|*Transcriptome Analysis|Viral Proteins|Downregulation|mRNA|Upregulation|HEK293 Cells 58 FSCN2 27811163 J. Cell Biol. 2016 PMC5119939 10.1083/jcb.201606036 14 10 0 24 Mice|Animals|*Stereocilia|plastin|Microfilament Proteins|*Actin Filament|fascin|Membrane Glycoproteins|FSCN1 protein, human|Hair Cells, Auditory|Carrier Proteins|Actin|Cochlea|Hearing|Utricle|Vestibule, Labyrinth 34 GNPTG 27729089 Arthritis Res. Ther. 2016 PMC5059912 10.1186/s13075-016-1135-6 2 1 0 56 *Autoantibodies|*Rheumatoid Arthritis|Autoantigens|Peptides, Cyclic|Immunoglobulin G|Immunoglobulin M|Enzyme-Linked Immunosorbent Assay 50 GNPTG 27241848 Biochim. Biophys. Acta 2016 PMC4949139 10.1016/j.bbagen.2016.05.029 3 15 0 56 Animals|*Mucolipidoses|*Zebrafish|*Mannose|*Phosphorylation|*Cathepsin|mannose-6-phosphate|Mannosephosphates|Transferases (Other Substituted Phosphate Groups)|N-acetylglucosamine kinase|*Phosphotransferases (Alcohol Group Acceptor)|Phenotypes|Lysosomes|Mutations|Glycosidases 50 GNPTG 27239697 Biochim. Biophys. Acta 2016 10.1016/j.bbadis.2016.05.018 4 3 0 56 Humans|Mice|Animals|*Mannose|X-Ray Microtomography|Mucolipidosis II|mannose-6-phosphate|*Mannosephosphates|Transferases (Other Substituted Phosphate Groups)|Niemann-Pick disease, type C2|Niemann-Pick Disease, Type C|*Hydrolases|Lysosomes|Phenotype|*Bone|Osteoclasts|Mutation|Disease Models, Animal|Fucosidase|Fibroblasts|Phosphates 50 GNPTG 27038293 Hum. Mutat. 2016 PMC4907843 10.1002/humu.22993 1 9 0 56 Humans|*Mucolipidoses|*Mutation, Missense|Transferases (Other Substituted Phosphate Groups)|N-acetylglucosamine kinase|*Phosphotransferases (Alcohol Group Acceptor)|Mutations|mannose-6-phosphate|Mannosephosphates|Phenotype|Lysosomes|Hydrolases|GNPTG protein, human 50 GSDMC 27835699 PLoS ONE 2016 PMC5105946 10.1371/journal.pone.0166422 8 8 0 11 Mice|Animals|*Colorectal Cancer|TGFBR2 protein, human|TGFBR2|*Colonic Neoplasms|Receptors, Transforming Growth Factor beta|*Upregulation|*Transcriptional Activation|*Receptors, Growth Factor|Adenomatous Polyposis Coli Protein|Signal Transduction|Protein-Serine-Threonine Kinases|Carcinogenesis|Adenocarcinoma|*Transforming Growth Factor|Transforming Growth Factor beta|Gene Expression Regulation, Neoplastic|Mutation|Intestinal Epithelium 19 GSDMC 27281216 Nature 2016 10.1038/nature18590 269 1 3 11 Animals|Pyroptosis|Caspases|Neoplasm Proteins|Inflammasomes|Cardiolipin|Phosphoinositides|Plasma Membrane|Necrosis|Liposomes|*Biological Transport 19 HEPACAM 27819278 Sci Rep 2016 PMC5098153 10.1038/srep36218 6 16 1 129 GJA1 protein, human|*Connexin 43|Neurodegenerative Diseases|Megalencephalic leukoencephalopathy with subcortical cysts|Hereditary Central Nervous System Demyelinating Diseases|*Cell Junctions|Gap Junctions|Cysts|Cell Cycle Proteins|Membrane Proteins|Astrocytes|Mutations|Cell Cycle 70 HEPACAM 27389245 Metab Brain Dis 2016 10.1007/s11011-016-9861-7 1 0 1 129 Humans|Megalencephalic leukoencephalopathy with subcortical cysts|*Founder Effect|Egypt|*Hereditary Central Nervous System Demyelinating Diseases|*Cysts|*Megalencephaly|Mutation|Membrane Proteins|Cell Cycle Proteins|Brain|Phenotype|*Nervous System Malformations|Missense Mutation|Haplotype|MLC1 protein, human|HEPACAM protein, human|Proteins 70 HEPACAM 27322623 PLoS ONE 2016 PMC4913951 10.1371/journal.pone.0157258 5 2 1 129 Humans|Megalencephalic leukoencephalopathy with subcortical cysts|*Follow-Up Studies|Hereditary Central Nervous System Demyelinating Diseases|*Cysts|*Megalencephaly|*Chinese|Membrane Proteins|Mutation|Cell Cycle Proteins|*Nervous System Malformations 70 HPS3 27593200 Pigment Cell Melanoma Res 2016 10.1111/pcmr.12534 5 0 0 43 Humans|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|*Hermanski-Pudlak Syndrome|Dilution, Pigmentary|*Mutations|*Sequencing, Next-Generation|*Hypopigmentation|*Chinese|Carrier Proteins|Membrane Proteins|Pedigree|Alleles|HPS3 protein, human 51 HPS6 27917594 Pediatr Blood Cancer 2016 10.1002/pbc.26320 1 0 0 1552 Humans|Adolescent|Child|*Hermanski-Pudlak Syndrome|*Mepacrine|Phenotype|Blood Platelet Disorders|*Secretory Vesicles|Blood Platelets|*Nucleotides|Pedigree|Genotype|Frameshift Mutation|Intracellular Signaling Peptides and Proteins|HPS6 protein, human 44 HPS6 27889498 J Genet Genomics 2016 PMC5199771 10.1016/j.jgg.2016.09.007 4 5 0 1552 Humans|Mice|Animals|*von Willebrand Factor|*Endothelial Cells|Weibel-Palade Bodies|Hermansky Pudlak Syndrome|von Willebrand Diseases|Adaptor Protein Complex 3|DDAVP|Hemostasis|Exocytosis|Lysosome|Endothelium|Disease Models, Animal|Protein Sorting|HPS6 protein, human|Intracellular Signaling Peptides and Proteins|Hps6 protein, mouse|Vesicular Transport Proteins 44 HPS6 27641950 Mol. Genet. Metab. 2016 PMC5083180 10.1016/j.ymgme.2016.08.009 4 0 0 1552 Humans|Male|*Hemophilia B|Hermansky Pudlak Syndrome|Platelet Storage Pool Deficiency|Phenotype|Mutation|Blood Platelets|HPS6 protein, human|Intracellular Signaling Peptides and Proteins 44 HPS6 27593200 Pigment Cell Melanoma Res 2016 10.1111/pcmr.12534 5 0 0 1552 Humans|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|*Hermanski-Pudlak Syndrome|Dilution, Pigmentary|*Mutations|*Sequencing, Next-Generation|*Hypopigmentation|*Chinese|Carrier Proteins|Membrane Proteins|Pedigree|Alleles|HPS3 protein, human 44 HPS6 27595926 Dev. Biol. 2016 10.1016/j.ydbio.2016.08.020 2 0 0 1552 Humans|Mice|Animals|*Hermanski-Pudlak Syndrome|*Tadpoles|*Xenopus|Melanosomes|Phenotype|*Organogenesis|Mutations|Pigmentation|Melanophores|Carrier Proteins|Gene Mapping|Melanocytes|Melanin|Lysosome|Allele|Disease Models, Animal 44 HPS6 27225848 J. Hum. Genet. 2016 10.1038/jhg.2016.56 2 0 0 1552 Humans|*Hermanski-Pudlak Syndrome|*Albinism, Ocular|*Whole Exome Sequencing|Japan|*Sisters|Mutations|Pedigree|Phenotype|High-Throughput Nucleotide Sequencing|Intracellular Signaling Peptides and Proteins|Platelets|HPS6 protein, human 44 HPS6 26823395 Br J Ophthalmol 2016 10.1136/bjophthalmol-2015-308067 1 0 0 1552 *Hermanski-Pudlak Syndrome|Pedigree|Phenotype|*Eyes|High-Throughput Nucleotide Sequencing|Genotype|Mutation|Intracellular Signaling Peptides and Proteins 44 IFNE 27510566 Genome Res. 2016 PMC5052048 10.1101/gr.203521.115 12 0 0 58 Pregnancy|Animals|Female|*Mammals|*Genomes|*Eutheria|Phylogeny|Chromosome Mapping 19 IFNE 27270441 Oncogene 2016 PMC5140783 10.1038/onc.2016.172 24 3 1 58 Humans|*Urinary Bladder Neoplasms|MTOR protein, human|TOR Serine-Threonine Kinases|DNA Copy Number Variations|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Genomics|Tumor Cell Lines|Exomes|Phosphatidylinositol 3-Kinases|Mutation|Computational Biology|Cisplatin|*Carcinoma, Transitional Cell|Gene Expression Profiling|Genes, p16|Signal Transduction|5'-methylthioadenosine phosphorylase 19 IMPG2 27930731 PLoS ONE 2016 PMC5145218 10.1371/journal.pone.0167909 5 0 0 17 Humans|*Autoimmune Diseases|*Retinal Diseases|*Autoantibodies|Retina|Recoverin|Autoantigens|Paraneoplastic Syndromes|Eye Proteins|Phosphopyruvate Hydratase|Blotting, Western 26 IRX2 27783221 Brain Struct Funct 2016 10.1007/s00429-016-1326-6 3 0 0 141 Animals|Transcription Factors|*Chickens|Homeodomain Proteins|Ear, Inner|Gene Expression Regulation, Developmental|Embryonic Development|Vertebrate|Epithelium|Cell Differentiation 71 IRX2 27496188 Medicina (Kaunas) 2016 10.1016/j.medici.2016.04.001 1 0 0 141 Macular dystrophy, retinal, 1, North Carolina type|DNA Copy Number Variations|Macular Dystrophy, Retinal, 2|*Corneal Dystrophies, Hereditary|*Genetic Linkage|Fluorescein Angiography|Pedigree|Retina|Tomography, Optical Coherence|Macular Dystrophy|Eye Proteins|Phenotype|Retinal Dystrophies|Transcription Factors 71 IRX2 27273073 Dev. Growth Differ. 2016 10.1111/dgd.12293 12 4 0 141 *Hindbrain|*Mesencephalon|transcription factor PEA3|Transcription Factors|Otx Transcription Factors|FGF8 protein, human|*Fibroblast Growth Factor 8|Trans-Activators|Organizers, Embryonic|Body Patterning|Gene Expression Regulation, Developmental|Prosencephalon|Zebrafish Proteins|*Signal Transduction|PAX2 Transcription Factor|Nerve Tissue Proteins|Wnt1 Protein|Fibroblast Growth Factors 71 IRX2 27172222 G3 (Bethesda) 2016 PMC4889666 10.1534/g3.116.029975 5 0 1 141 Animals|Mice|*Scoliosis|*Kyphosis|Allele|Genetic Linkage|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Homeodomain Proteins|Chromosome Mapping|Transcription Factors|Zebrafish|Regulatory Sequences, Nucleic Acid|Genetic Heterogeneity|Base Sequence|*Chromosome Structures|Irx4 protein, mouse 71 IRX2 26977395 Mol Metab 2016 PMC4770267 10.1016/j.molmet.2016.01.002 66 6 2 141 Humans|Mice|Animals|*Chromatin Immunoprecipitation Sequencing|Diabetes Mellitus, Type 2|*RNA-Seq|*Insulin-Secreting Cells|*Glucagon-Secreting Cells|Chromatin|Chromatin Immunoprecipitation|Islets of Langerhans|*Whole Exome Sequencing|High-Throughput Nucleotide Sequencing|Genome-Wide Association Study|Transcriptomes 71 KIAA0586 27146717 Elife 2016 PMC4858382 10.7554/eLife.12950 28 44 2 86 Humans|*E3 Ligase|Centrioles|Ubiquitylation|Cell Cycle Proteins|Cilia|Microtubule-Associated Proteins|Protein Binding|Binding Protein|Autoantigens|HEK293 Cells|PCM1 protein, human|Talpid3 protein, human 27 KLHL7 27392078 Am. J. Hum. Genet. 2016 PMC5005468 10.1016/j.ajhg.2016.05.026 8 3 0 90 Child|Humans|Child, Preschool|Crisponi syndrome|*Hand Deformities, Congenital|*Facies|*Hyperhidrosis|*Trismus|*Death, Sudden|*Phenotype|*Alleles|*Mutations|Homozygote|Receptors, Cytokine|*Retinitis Pigmentosa|Sweating|Whole Exome Sequencing|Pedigree|Hyperthermia|KLHL7 protein, human|Autoantigens 30 LMOD2 27274810 Cell Biosci 2016 PMC4893230 10.1186/s13578-016-0101-y 5 6 1 42 Mice|Animals|Rats|*Cardiomyopathy, Dilated|Sarcomeres|Actin Cytoskeleton|Muscle Proteins|Myocardium|Skeletal Muscles|Muscle Contraction|Cardiomyocytes|Cytoskeletal Proteins|leiomodin 2 protein, rat|Microfilament Proteins 19 LMOD2 26873245 Biochim. Biophys. Acta 2016 PMC5079754 10.1016/j.bbapap.2016.02.009 8 25 1 42 *Tropomyosin|Tropomodulin|Actin Cytoskeleton|Sarcomeres|Actins|Binding Site|Muscle Proteins|Familial dilated cardiomyopathy|Cardiomyopathy, Dilated|Protein Binding|Amino Acid Sequence|Muscle, Striated|Muscle Cells, Cardiac|Muscle, Skeletal|Protein Domains 19 LMOD3 27632998 J. Cell. Sci. 2016 10.1242/jcs.190009 3 3 0 46 Mice|Animals|*Transcription Factor AP-1|*Heat Shock Protein|*Muscle Atrophy|FOSL2 protein, human|Fos-Related Antigen-2|fos-related antigen 1|Proto-Oncogene Proteins c-fos|Transcription, Genetic|Muscular Diseases|Myogenesis|Muscle, Skeletal|Proto-Oncogene Proteins c-jun|Myoblasts, Skeletal|Promoter Regions, Genetic|*Regulatory Sequences, Nucleic Acid|FLNC protein, human|Filamins|HSPB7 protein, mouse 22 LMOD3 27274810 Cell Biosci 2016 PMC4893230 10.1186/s13578-016-0101-y 5 6 1 46 Mice|Animals|Rats|*Cardiomyopathy, Dilated|Sarcomeres|Actin Cytoskeleton|Muscle Proteins|Myocardium|Skeletal Muscles|Muscle Contraction|Cardiomyocytes|Cytoskeletal Proteins|leiomodin 2 protein, rat|Microfilament Proteins 22 LOXHD1 27242896 Front Genet 2016 PMC4876112 10.3389/fgene.2016.00088 1 2 1 9 Humans|*Cleft Lip|*Cleft Palate|*Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genome-Wide Association Study|Genetic Loci|Genotype|Case-Control Studies|SKA1 protein, human|Chromosomal Proteins, Non-Histone 34 LOXHD1 27121161 Int. J. Mol. Med. 2016 PMC4866966 10.3892/ijmm.2016.2570 2 2 1 9 Humans|*Fuchs' Endothelial Dystrophy|Collagen Type VIII|Transcription Factor 4|Pedigree|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Single Nucleotide Polymorphisms|Genotype|Transcription Factors|Mutation|Genetic Linkage|Zinc Finger|Zinc Finger E-box-Binding Homeobox 1|ZEB1 protein, human|SLC4A11 protein, human|Antiporters|Anion Transport Proteins|COL8A2 protein, human|LOXHD1 protein, human 34 LOXHD1 26973026 Auris Nasus Larynx 2016 10.1016/j.anl.2016.02.010 5 0 0 9 Humans|Japan|*Hearing Loss|*Deafness|*Mutations|Hearing Loss, Sensorineural|Pedigree|Mutations, Missense|Heterozygote|Asian Continental Ancestry Group|High-Throughput Nucleotide Sequencing|Phenotype|Carrier Proteins|LOXHD1 protein, human 34 LYPLAL1 27773974 Ethn Dis 2016 PMC5072476 10.18865/ed.26.4.477 0 0 0 45 Overweight|Obesity|Body Mass Index|Gene Frequency|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|PPAR gamma|Case-Control Studies 71 MYO3A 27622050 Oncoimmunology 2016 PMC5006911 10.1080/2162402X.2016.1196299 6 2 0 81 Humans|Animals|Chick Embryo|Mice|*Up-Regulation|*BALB C Mice|*Macrophages|MCF 7 Cells|Neoplasm Invasiveness|Matrix Metalloproteinase 9|*Macrophage Inflammatory Proteins|Cell Movement|Signal Transduction|Cell Line, Tumor|Tumor Microenvironment|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Paracrine Communication|MYO3A protein, human|Myosin Heavy Chains|Myosin Type III|MYO3A protein, mouse 50 MYO3A 27582493 J. Biol. Chem. 2016 PMC5077211 10.1074/jbc.M116.733741 1 0 0 81 Humans|Animals|Chlorocebus aethiops|*Actins|Myosin Type III|*Myosins|Filopodia|Stereocilia|Myosin Heavy Chains|COS Cells|Protein Binding|Myosin B 50 MYO3A 27063751 Int. J. Pediatr. Otorhinolaryngol. 2016 10.1016/j.ijporl.2016.02.036 1 0 0 81 Humans|Deafness, Autosomal Recessive 30|*Hearing Loss, Sensorineural|*Hearing Impairment|Myosin Type III|*Homozygote|*Chinese|Deafness|Myosin Heavy Chains|Mutations|Pedigree|Genetic Loci|MYO3A protein, human 50 MYO3A 27014590 Meta Gene 2016 PMC4792891 10.1016/j.mgene.2016.02.002 2 0 1 81 Humans|Greece|Retinitis Pigmentosa|*Retina|Genes, Recessive|Exons|Pedigree|Retinal Dystrophies|Macular Degeneration|Mutation|ATP-Binding Cassette Transporters|Stargardt Disease|Heterogeneities, Genetic|Genomics|ABCA4 protein, human 50 MYO3A 26926603 Nat Commun 2016 PMC4773517 10.1038/ncomms10833 20 22 1 81 50 MYO3A 26841241 Hum. Mutat. 2016 PMC4833613 10.1002/humu.22961 5 12 1 81 Chlorocebus aethiops|Animals|Humans|Myosin Type III|Stereocilia|Filopodia|Myosin Heavy Chains|Actins|Hearing Loss, Sensorineural|Deafness|Hair Cells, Auditory, Inner|*Protein Isoforms|Hearing Loss|COS Cells|Mutant Protein|Cell Movement|Mutation|MYO3A protein, human 50 MYO3A 26785147 Elife 2016 PMC4758956 10.7554/eLife.12856 5 48 1 81 Chlorocebus aethiops|Animals|*Myosin Type III|*Myosin B|*Actins|Myosins|Microfilament Proteins|Stereocilia|Myosin Heavy Chains|Pseudopodia|COS Cells 50 MYO3A 26754646 J. Cell Biol. 2016 PMC4738386 10.1083/jcb.201509017 14 13 2 81 Chlorocebus aethiops|Mice|Animals|*Stereocilia|*Myosin B|*Microvilli|Myosin Type III|Myosins|Hair Cells, Auditory|Myosin Heavy Chains|Actins|Cochlea|Hearing|COS Cells|*Biological Phenomena|MYO3A protein, mouse|MYO3B protein, mouse 50 MYPN 28017374 Am. J. Hum. Genet. 2016 PMC5223057 10.1016/j.ajhg.2016.11.017 19 6 0 235 Adult|Humans|Mice|Animals|Child|Intranuclear Rod Myopathy|*Myopathies, Nemaline|Skeletal Muscles|Muscle Proteins|Muscular Diseases|Muscular Weakness|Actins|Mutations|Homozygote|Pedigree|Hypotonia|Sequencing, Whole Exome|Electron Microscopy|MYPN protein, human 32 PASD1 26892021 J Mol Cell Biol 2016 10.1093/jmcb/mjw005 9 13 0 15 Mice|Male|Animals|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|Mice, Nude|*Cell Nucleus|Phosphorylation|Protein Tyrosine Phosphatase, Non-Receptor Type 2|Oncogenesis|Signal Transduction|Cell Proliferation|*Genes, Regulator|Cell Line, Tumor|Gene Expression Regulation|Protein Binding|Cell Migration 19 PCDH12 27164683 Neurology 2016 PMC4887125 10.1212/WNL.0000000000002704 7 1 0 30 Female|Pregnancy|Humans|*Microcephaly|Brain|Epilepsy|Phenotype|Pedigree|Exome|Mutation|Infections|PCDH12 protein, human|Cadherins 27 PCDH12 27018791 PLoS ONE 2016 PMC4809512 10.1371/journal.pone.0152227 13 1 1 30 Humans|Mice|Pregnancy|Female|Animals|*C57BL Mice|*Fetal Growth|Placental Development|Placenta|Trophoblasts|Fetal Weight|Placental Hormones|Fetal Growth Retardation|Maternal Nutritional Physiological Phenomena|Low Protein Diet|TYRP1 protein, human|Fetuses|*Membrane Glycoproteins|*Body Weights and Measures|PCDH12 protein, human|Cadherins|Pcdh12 protein, mouse 27 PDE6H 28017720 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.12.141 0 3 0 11 Humans|Animals|Mice|*Myocyte Enhancer Factor 2C|*Retina|Retinal Rod Photoreceptor Cells|*Gene Expression|Cyclic Nucleotide Phosphodiesterases, Type 6|Eye Proteins|Homeodomain Proteins|Trans-Activators|Gene Expression Regulation|Rhodopsin|Basic-Leucine Zipper Transcription Factors|MAPK15 protein, human|Extracellular Signal-Regulated MAP Kinases|MEF2C protein, human|Mef2c protein, mouse 27 PDE6H 27915366 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. 2016 10.1007/s00360-016-1052-7 1 0 0 11 Male|Animals|Rats|*Leydig Cells|*Cyclic GMP|GUCY1B3 protein, human|Soluble Guanylyl Cyclase|Testosterone|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|GUCY1A3 protein, human|Cyclic GMP-Dependent Protein Kinases|Cyclic AMP|adenylate cyclase 9|Adenylyl Cyclases|Guanylate Cyclase|Androgens|Signal Transduction|Luteinizing Hormone|Rats, Wistar|*Aging 27 PDE6H 27472364 Genes (Basel) 2016 PMC4999829 10.3390/genes7080041 2 0 1 11 Male|Blue cone monochromatism|*Color Vision Defects|Pakistan|Hypotrichosis, Localized, Autosomal Recessive, 3|Hypotrichosis|*Alopecia|Hair Diseases|Genes, Recessive|Pedigree|Homozygote|Phenotype|Receptors, Lysophosphatidic Acid|Mutation|Codon, Nonsense|Retinal Cone Photoreceptor Cells|Family Members 27 PDE6H 27296292 BMC Evol. Biol. 2016 PMC4906994 10.1186/s12862-016-0695-z 11 5 3 11 Animals|*Cyclic Nucleotide Phosphodiesterases, Type 6|Phylogeny|Retinal Rod Photoreceptor Cells|Retinal Cone Photoreceptor Cells|*Vertebrate|Phototransduction|Genomes|Evolution, Molecular|Synteny|Gene Expression 27 PDE6H 27040408 Jpn. J. Ophthalmol. 2016 10.1007/s10384-016-0424-6 3 0 0 11 Humans|Achromatopsia 1|*Color Vision Defects|*Gated Channel, Cyclic-Nucleotide|*Retinal Cone Photoreceptor Cells|Japan|Electroretinography|DNA Mutational Analysis|Mutation|Pedigree|Visual Acuity|Nucleotides, Cyclic 27 PLCL2 27440135 Scand. J. Rheumatol. 2016 10.1080/03009742.2016.1199734 2 2 0 21 *Arthritis, Psoriatic|Greece|PTPN22 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 22|*Rheumatoid Arthritis|Single Nucleotide Polymorphisms|STAT4 Transcription Factor|Genetic Predisposition to Disease|Genetic Association Studies|Gene Frequency|Alleles|Case-Control Studies|Genotype|Autoimmune Diseases 19 POU5F1B 26934861 Sci Rep 2016 PMC4776156 10.1038/srep22462 17 4 3 44 Humans|Male|Genome-Wide Association Study|AR protein, human|Androgen Receptor|Prostate Cancer|Prostate|Gene Expression Regulation, Neoplastic|Hepatocyte Nuclear Factor 3-alpha|Polymorphism, Single Nucleotide|Enhancer Elements, Genetic|Androgens|Cell Line, Tumor|Sequencing, Next-Generation|Genes, Homeobox 19 PRCD 27830106 Tremor Other Hyperkinet Mov (N Y) 2016 PMC5099978 10.7916/D8GB24C5 1 0 1 11 *Torticollis|*Deglutition Disorders|*Retrospective Studies|Neuromuscular Agents|Botulinum Toxins, Type A|*Parkinsonism|Injection|Goals 66 PRCD 27613864 J. Biol. Chem. 2016 PMC5087724 10.1074/jbc.M116.742767 3 1 0 11 Mice|Animals|*Lipoylation|*Cone-Rod Degeneration|Retinitis Pigmentosa|*Cone Dystrophy|Eye Proteins|Membrane Proteins|*Protein Stability|Golgi Apparatus|Mutation|PRCD protein, mouse 66 PRCD 27509380 Biochemistry 2016 PMC5513659 10.1021/acs.biochem.6b00489 9 3 0 11 Humans|Animals|Dogs|*Rhodopsin|Proteomics|*Cone-Rod Degeneration|*Cone Dystrophy|Retinal Degeneration|TYRP1 protein, human|*Membrane Glycoproteins|Eye Proteins|Retinitis Pigmentosa|Photoreceptor Cells|Membrane Proteins|*Acylation|*Cytoplasm 66 PRCD 27293555 J Nutr Sci 2016 PMC4891559 10.1017/jns.2016.5 2 0 1 11 Humans|Animals|Dogs|Infant|*Antioxidants|*Retina|Electroretinography|Retinal Cone Photoreceptor Cells|Color Vision|*Refractive Error|Photic Stimulation|Dietary Supplements 66 PRCD 27252624 Front Cell Neurosci 2016 PMC4879145 10.3389/fncel.2016.00141 2 4 1 11 Animals|Mice|Child|Cerebellar Hypoplasia|reelin protein|Cell Adhesion Molecules, Neuronal|*Cerebellum|Extracellular Matrix Proteins|Serine Endopeptidases|Reeler Mouse|*Nervous System Malformations|Nerve Tissue Proteins|*Developmental Disabilities|*Cell Proliferation|*Apoptosis|Neurons|Cerebellar Cortex|Densities, Cell|BrdU|Interneurons|Phenotype 66 RNASEH2A 27988520 Oncology 2016 10.1159/000452281 7 0 0 81 *B-DNA|*Colorectal Cancer|*Colon Cancer|Prognosis|Biomarkers, Tumor|*Endonucleases|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|*Disease Progression|RNA, Messenger|Real-Time Polymerase Chain Reaction|*Gene Expressions 41 rtn2 26906425 J. Cell. Sci. 2016 PMC4852773 10.1242/jcs.184929 27 2 0 109 Animals|*Drosophila melanogaster|Spastic paraplegia 12, autosomal dominant|Hereditary Spastic Paraplegia|Spastic paraplegia 3, autosomal dominant|GTPase|Endoplasmic Reticulum|Membrane Proteins|GTP-Binding Proteins|Membrane Fusion|Mutations|Neurons 23 rtn2 28603788 J Rare Dis Res Treat 2016 PMC5462091 1 9 0 109 Animals|*Rare Diseases|Spastic Paraplegias, Hereditary|Endoplasmic Reticulum|Axons|Membrane Proteins|Motor Neurons|Drosophila melanogaster|Membrane Transport Proteins|Mutations|Retrograde Degeneration|Disease Models, Animal 23 s100a5 28017722 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.12.143 4 5 0 15 AGER protein, human|Receptor for Advanced Glycation End Products|Protein Binding|S100 Proteins|Models, Molecular|Molecular Docking Simulation|*Biophysics|Ligands|NMR Spectroscopy|Calorimetry 39 s100a5 27689623 J Invest Surg 2016 10.1080/08941939.2016.1231855 2 0 0 15 *Alarmins|*Prospective Studies|Calgranulin A|HMGB1 Protein|*Abdomen|S100 Proteins|Intraoperative Complications 39 s100a5 27297108 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.06.041 4 4 0 15 Humans|*Pentamidine|*Signal Transduction|Protein Binding|S100 Protein Family|Receptor for Advanced Glycation End Products|Binding Sites|EF Hand Motifs|Nuclear Magnetic Resonance, Biomolecular|Molecular Docking Simulation|NMR Spectroscopy|Models, Molecular|Glycation End Products, Advanced|S100A5 protein, human 39 Six5 27864399 Int J Epidemiol 2016 PMC5837581 10.1093/ije/dyw245 7 0 0 112 Humans|Adult|*Coronary Artery Disease|Genome-Wide Association Study|Cross-Sectional Studies|*Genetic Loci|*Lipids|Cholesterol, HDL|Cholesterol, LDL|Polymorphism, Single Nucleotide|Triglycerides|Genetic Predisposition to Disease|Asian Continental Ancestry Group|European Continental Ancestry Group|Phenotype|Genotype|Lipid Metabolism 113 Six5 27821176 J Hematol Oncol 2016 PMC5100270 10.1186/s13045-016-0339-1 21 17 1 112 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Disease Progression 113 Six5 27399099 Medicine (Baltimore) 2016 PMC5058828 10.1097/MD.0000000000004085 18 8 1 112 Humans|Neoplasm Recurrence, Local|*Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Homeodomain Proteins|Proportional Hazards Models|Disease Progression 113 SMPX 27181368 Sci Rep 2016 PMC4867575 10.1038/srep25944 3 13 1 17 Humans|*Muscle Protein|Myoblasts|Myotubes|*Cell Differentiation|Muscle Development|Muscle, Skeletal|Transcriptional Activation|*Genes, X-Linked|DNA Binding Protein|*Receptors, Cytoplasmic and Nuclear|Up-Regulation|Promoter Regions, Genetic|SMPX protein, human 41 SMPX 27170199 Cardiovasc. Res. 2016 10.1093/cvr/cvw096 6 4 0 17 Animals|Hindlimb|Ischemia|Neovascularization, Physiologic|Endothelial Cells|*Protein Isoforms|CD146 Antigen|Cell Proliferation|Cell Movement|Cells, Cultured|Disease Models, Animal|Muscle, Skeletal 41 SNX14 27913285 Eur J Med Genet 2016 PMC5241222 10.1016/j.ejmg.2016.11.006 4 5 0 37 Humans|Child|Spinocerebellar ataxia 20|Spinocerebellar Ataxias|Purkinje Cells|Cerebellum|Ataxia|Ataxias, Hereditary|Cerebellar Ataxia|Sorting Nexins|Mutations|Autophagy|Phenotype|Intellectual Disability 22 SNX14 27566131 BMC Genet. 2016 PMC5002145 10.1186/s12863-016-0433-y 5 0 1 37 Dogs|Animals|*RNA Splice Sites|Hungary|Neurodegenerative Diseases|Purkinje Neurons|Cerebellar Ataxia|Cerebellum|Spinocerebellar Degenerations|*Mutation|*Chromosome Mapping|*Base Sequence|Dog Diseases|Breeding 22 SPATA5 27246907 Clin. Genet. 2016 10.1111/cge.12813 7 0 1 119 Child|Child, Preschool|Humans|Spasms, Infantile|*Encephalopathy|Microcephaly|Seizures|Intellectual Disability|Electroencephalography|Facies|Sequencing, Whole Exome|Mutations|Neuroimaging|Pedigree|Psychomotor Disorders|Phenotype|Homeodomain Proteins|Hearing Loss|Imaging, Magnetic Resonance|SPATA5 protein, human|ATPases Associated with Diverse Cellular Activities 19 SPATA5 27683084 Orphanet J Rare Dis 2016 PMC5041579 10.1186/s13023-016-0509-9 0 0 1 119 Humans|*Intellectual Disability|*Muscle Hypotonia|*Hearing Loss|*Phenotype|*Deafness|*Mutations|Microcephaly|Exome|Infantile Spasms|Hearing Loss, Sensorineural|Epilepsy|Homozygote|Pedigree|ATPases Associated with Diverse Cellular Activities|Alleles|SPATA5 protein, human 19 SPATA5 27305948 Sci Rep 2016 PMC4910105 10.1038/srep28111 3 3 1 119 Animals|Female|Male|*Vitellogenins|triazophos|Organothiophosphates|*Hemiptera|*Fecundity|Reproduction|Insect Proteins|Triazoles|TYRP1 protein, human|*Spermatogenesis|*Gene Expression|*Membrane Glycoproteins|Insecticides|Ovary|Longevity 19 SPATA5 26932830 Birth Defects Res. Part A Clin. Mol. Teratol. 2016 10.1002/bdra.23452 0 0 0 119 Pregnancy|Female|Humans|Child|*Cystic Adenomatoid Malformation of Lung, Congenital|*Meningocele|Fetal Diseases|Ultrasonography, Prenatal|*Spinal Dysraphism|Gestational Age|*Meningomyelocele|Cephalocele 19 TANGO2 27902461 Oncotarget 2016 PMC5341753 10.18632/oncotarget.13646 4 0 0 104 Male|Humans|*Whole Exome Sequencing|*Case-Control Studies|Chad|Genetic Predisposition to Disease|Alleles|*Prostate Cancer|Exome|Polymorphism, Single Nucleotide|Genotype|Mutations|HOXB13 protein, human|Homeodomain Proteins 23 TANGO2 26805782 Am. J. Hum. Genet. 2016 PMC4746337 10.1016/j.ajhg.2015.12.009 18 0 0 104 Child|Humans|Infant|Mice|Animals|Disorders, Mitochondrial|*Alleles|Exome|Pedigree|Mitochondria|Arrhythmias, Cardiac|Whole Exome Sequencing|Rhabdomyolysis|Golgi Apparatus|Mutation 23 taok2 27934295 J. Proteome Res. 2016 PMC5642956 10.1021/acs.jproteome.6b00613 6 15 0 143 Humans|*Proto-Oncogene Proteins B-raf|*Protein Kinase Inhibitors|*Signal Transduction|Melanoma|Vemurafenib|dabrafenib|Oximes|Drug Resistance, Neoplasm|Imidazoles|Cell Line, Tumor|Indoles|TYRP1 protein, human|*Membrane Glycoproteins|Sulfonamides|Mutation|Apoptosis|BRAF protein, human 19 taok2 27426302 Bioorg. Med. Chem. Lett. 2016 10.1016/j.bmcl.2016.07.016 1 0 0 143 Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Structure-Activity Relationship|Small Molecule Libraries|Protein Kinase Inhibitors|High-Throughput Screening Assays|MAP Kinase, p38|Drug Discovery|Phosphorylation|Protein-Serine-Threonine Kinases|Models, Molecular|Adenosine Triphosphate|Cell Line, Tumor 19 taok2 27107179 Comput Biol Chem 2016 10.1016/j.compbiolchem.2016.04.003 2 0 0 143 Humans|*5' Untranslated Regions|*miRNAs|CASP3 protein, human|*Caspase 3|*Polymorphism, Single Nucleotide|*Open Reading Frames|3' Untranslated Regions|Binding Sites|RNA, Messenger|Exons|Genomics|ZNF346 protein, human|DNA-Binding Proteins|RNA-Binding Proteins 19 TSPEAR 27736875 PLoS Genet. 2016 PMC5065119 10.1371/journal.pgen.1006369 5 6 1 2 Humans|Mice|Animals|*Hair Follicle|Dysplasias, Ectodermal|*Signal Transduction|*Mutations|Notch1 Protein|gephyrin|Membrane Proteins|Hair|Pedigree|Carrier Proteins|*Organogenesis|Phenotype|Hypotrichosis|Gene Expression Regulation, Developmental|TSPEAR protein, human|Proteins 19 TSPEAR 27138532 Cancer Immunol. Immunother. 2016 PMC5424608 10.1007/s00262-016-1842-5 14 11 0 2 Cancer|Adoptive Immunotherapy|*Immunotherapy|Receptors, Antigen, T-Cell|T Cells|T-Cell Specificity|Antigens, Neoplasm|Genetic Engineering 19 TSPEAR 26921345 J. Leukoc. Biol. 2016 PMC4982612 10.1189/jlb.2A1215-561R 9 0 1 2 *Hepacivirus|*Hepatitis C|*Cross Reactions|Receptors, Antigen, T-Cell|*TcR Gene|Epitopes, T-Lymphocyte|CD8-Positive T-Lymphocytes|*Immunotherapy|*Genomic Instability|Mutations|*Immunologic Factors 19 TXNDC12 27765924 Oncotarget 2016 PMC5342147 10.18632/oncotarget.12290 33 14 0 67 Humans|*Carcinoma, Squamous Cell|RNA, Micro|*Carcinoma, Non-Small-Cell Lung|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Gene Expression Profiling|Oncogenes|Down-Regulation|Gene Knockdown Techniques|RNA, Messenger|Oncogenesis|*Genes, Tumor Suppressor|Lung Neoplasms|LMAN1 protein, human|Membrane Proteins|Mannose-Binding Lectins 19 TXNDC12 27026037 Fish Shellfish Immunol. 2016 10.1016/j.fsi.2016.03.154 0 2 0 67 Animals|Hydrogen Peroxide|Edwardsiella tarda|Streptococcus iniae|Iridoviridae|Fish Proteins|Perciformes|Iridovirus|DNA Virus Infections|TXN protein, human|Thioredoxin|Fish Diseases|Poly I-C|*Oxidative Stress|Amino Acid Sequence|Sequence Alignment|Gene Expression Regulation|mRNA|Enterobacteriaceae Infections 19 USB1 27612988 Haematologica 2016 PMC5046647 10.3324/haematol.2016.147769 6 0 0 66 Humans|*Dyskeratosis Congenita|*Syndrome|Dubowitz syndrome|Microcephaly|Homozygote|Mutations|Exome|Telomere Shortening|Telomere|Intellectual Disability|Facies|Nuclear Proteins|Mutation, Missense|Growth Disorders|Eczema|GRHL2 protein, human|DNA-Binding Proteins|Transcription Factors 34 USB1 27247962 Mol Genet Genomic Med 2016 PMC4867568 10.1002/mgg3.209 4 0 1 66 Humans|*Rothmund-Thomson Syndrome|RECQL4 protein, human|*RecQ Helicases|Poikiloderma with Neutropenia|Neutropenia|Dyskeratosis Congenita|Genotype|Mutation|Phenotype|USB1 protein, human|Phosphoric Diester Hydrolases 34 USB1 26987923 Stem Cell Res 2016 10.1016/j.scr.2015.10.006 0 0 0 66 Humans|Infant|Poikiloderma with Neutropenia|*Induced Pluripotent Stem Cells|*Skin Abnormalities|*Neutropenia|RNA, Small Nuclear|RNA Splicing|Phosphoric Diester Hydrolases|Mutation 34 USB1 26923089 Physiol Plant 2016 10.1111/ppl.12439 2 0 0 66 *Saccharomyces cerevisiae|Arabidopsis|Arabidopsis Proteins|Gene Expression Regulation, Plant|Transcription Factors|Plants, Genetically Modified|Zinc Finger|Abiotic Stress|*Yeast, Dried|Reactive Oxygen Species|Signal Transduction|Sodium Chloride|Oxidative Stress|Gene Expression Profiling|ZAT12 protein, Arabidopsis 34 USP9Y 27333765 Chromosome Res. 2016 10.1007/s10577-016-9531-y 3 0 0 19 Male|Mice|Animals|*Genes, Y-Linked|*Y Chromosomes|*Murinae|*Translocation, Genetic|X Chromosome|Sex-Determining Region Y Protein|Chromosome Structures|DNA-Binding Proteins|Genome|Chromosome Mapping|In Situ Hybridization, Fluorescence|Gene Dosage|Amino Acid Sequence 80 USP9Y 27284354 Exp Ther Med 2016 PMC4887809 10.3892/etm.2016.3252 4 0 0 19 Humans|*Computational Biology|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Profile, Gene Expression|Gene Expression Profiling|Databases, Genetic|Software|*Heart Failure|Gene Expression Regulation, Neoplastic|Microarray Analysis|Signal Transduction|Upregulation|*Myocardial Ischemia|Cardiomyopathies 80 USP9Y 27058445 Am. J. Hum. Genet. 2016 PMC4833433 10.1016/j.ajhg.2016.02.023 19 0 1 19 Humans|Male|Animals|*Neanderthals|*Chromosomes, Human, Y|Hominids|Chimpanzee|Genetic Variation|Genome, Human|Phylogeny|DNA|Exome|Base Sequence|Polymorphism, Single Nucleotide|Spain|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases 80 USP9Y 26829740 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2016 10.3760/cma.j.issn.1003-9406.2016.01.019 0 0 0 19 Humans|*Cytogenetic|Sex Chromosome Aberrations|*Genetic Markers|Chromosomes, Human, Y|In Situ Hybridization, Fluorescence|Chromosome Deletion 80 wdfy1 27026195 Sci Rep 2016 PMC4812299 10.1038/srep23588 8 10 1 79 neuropilin-2, human|Neuropilin-2|Neuropilin-1|Signal Transduction|Vascular Endothelial Growth Factor A|Gene Expression Regulation|plexin|Nerve Tissue Proteins|Vascular Endothelial Growth Factors|2,5-dichloro-4-bromophenol|*Chlorophenols|Transcription Factor|Cell Line, Tumor|Autophagy|Cell Movement 19 WDR11 27974186 Best Pract. Res. Clin. Endocrinol. Metab. 2016 10.1016/j.beem.2016.11.008 6 0 0 50 Child|Humans|Combined Pituitary Hormone Deficiency|Hypopituitarism|Pituitary dwarfism 1|*Dwarfism, Pituitary|Gland, Pituitary|Pituitary Diseases|Transcription Factors|Human Growth Hormone|Homeodomain Proteins|Pituitary Gland, Posterior|Hypothalamus|Mutations|Genes, Homeobox|Magnetic Resonance Imaging 36 WDR11 26813131 Zhonghua Yi Xue Za Zhi 2016 1 0 0 50 Male|Humans|*Hypogonadism|Kallmann Syndrome|*Mutation|Receptor, Fibroblast Growth Factor, Type 1|Extracellular Matrix Proteins|Nerve Tissue Proteins 36 5HT1 26639667 Neurobiol Learn Mem 2015 10.1016/j.nlm.2015.11.011 0 0 0 0 Mice|Animals|*Avoidance Learning|A18Famide|*Neurotransmitters|neuropeptide B|Neuropeptides|*Oligopeptides|RFamide peptide|Dopamine Antagonists|Haloperidol|Adrenergic Antagonists|Bicuculline|Narcotic Antagonists|Memory|Atropine|Naloxone|Propranolol|Anxiety|Prazosin 176 5HT1 26174731 BMJ Case Rep 2015 PMC4513583 10.1136/bcr-2015-210726 2 0 0 0 Humans|Aged|*Trazodone|Antidepressive Agents, Second-Generation|Serotonin Uptake Inhibitors|Insomnia|Anxiety|Anti-Anxiety Agents|Anxiety Disorders|Depression|Depressive Disorder, Major|Serotonin 176 5HT1 26044059 BMJ Clin Evid 2015 PMC4456852 2 0 0 0 Child|Humans|Adult|Sexual Maturation|*Headache, Migraine|Acetaminophen|Anti-Inflammatory Agents, Non-Steroidal 176 5HT1 25656001 J Ethnopharmacol 2015 10.1016/j.jep.2015.01.029 4 1 0 0 Mice|Animals|*Tilia|*Flavonoids|Anti-Anxiety Agents|Traditional Medicine|Phytotherapy|Hypnotics and Sedatives|Plant Extracts|Chromatography, High Pressure Liquid|Maze Learning|Behavior, Animal|Motor Activity|Flowers|Mexico 176 APMAP 25628020 BMC Bioinformatics 2015 PMC4314935 10.1186/s12859-015-0468-5 6 1 0 44 Humans|*Glycosylation|Glycoproteins|Cell Adhesion Molecules, Neuronal|Amino Acid Sequence|Protein Binding|Cell Adhesion 19 atad5 26177013 Cell Cycle 2015 PMC4825795 10.1080/15384101.2015.1068475 7 1 0 147 Humans|Mice|Animals|*Phosphorylation|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|DNA Replication|DNA Damage|Stability, Genome|RTEL1 protein, human|DNA Helicases|DNA Repair|Methyl Methanesulfonate|Proliferating Cell Nuclear Antigen|Telomeres|DNA-Binding Proteins|Carrier Proteins|Genotoxins|Protein-Serine-Threonine Kinases|DNA|ATAD5 protein, human 35 atad5 25795125 Mutat Res Rev Mutat Res 2015 10.1016/j.mrrev.2014.11.007 9 25 0 147 Humans|Mice|Animals|*Stability, Genome|Saccharomyces cerevisiae|Replication Protein C|DNA Replication|DNA Repair|Saccharomyces cerevisiae Proteins|Proliferating Cell Nuclear Antigen|DNA-Binding Proteins|RTEL1 protein, human|DNA Helicases|Adenosine Triphosphatases|DNA Damage|ATPases Associated with Diverse Cellular Activities|Fanconi Anemia|Carrier Proteins|Chromosome Segregation|ATAD5 protein, human|ATAD5 protein, mouse 35 atad5 25581431 Nat. Genet. 2015 PMC4445140 10.1038/ng.3185 92 1 8 147 Humans|Female|*Carcinoma, Ovarian Epithelial|Genome-Wide Association Study|BRCA1 protein, human|BRCA1 Protein|*Ovarian Cancer|BRCA2 Protein|Neoplasms, Glandular and Epithelial|Genetic Predisposition to Disease|Cystadenocarcinoma, Serous|Polymorphism, Single Nucleotide|Alleles|Mutation|Genotype|SYNPO2 protein, human|Microfilament Proteins|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities|DNA-Binding Proteins 35 C12orf65 26556829 Brain 2015 PMC5839554 10.1093/brain/awv320 25 1 2 45 Humans|Adolescent|Leukodystrophy, Dysmyelinating, And Spastic Paraparesis With Or Without Dystonia|MAST Syndrome|Spastic paraplegia 15, autosomal recessive|Spastic paraplegia 11, autosomal recessive|*Spastic Paraplegia, Hereditary|Charcot-Marie-Tooth disease, Type 2B2|Charcot-Marie-Tooth disease, Type 2B1|Charcot-Marie-Tooth disease, Type 2H|Charcot-Marie-Tooth disease, Type 2K|Charcot-Marie-Tooth Disease, Axonal, Type 2A2|*Charcot-Marie-Tooth Disease|*Mutations|Genes, Recessive|Pedigree|*Axons|Amyotrophic Lateral Sclerosis, Autosomal Recessive|Amyotrophic Lateral Sclerosis|Genetic Linkage 26 C12orf65 26187298 J. Neurol. Sci. 2015 10.1016/j.jns.2015.07.009 2 0 1 45 Behr syndrome|*Intellectual Disability|*Optic Atrophy|*Ataxia|*Spasm|*Hearing Loss|*Homozygote|*Mutation|GTP Phosphohydrolases|Heterozygote|Mitochondrial Proteins 26 C12orf65 30838228 Mov Disord Clin Pract 2015 PMC6353461 10.1002/mdc3.12184 1 0 1 45 *Spastic Paraplegia, Hereditary|Mutation 26 C12orf65 25995486 J. Neurol. Neurosurg. Psychiatry 2015 10.1136/jnnp-2014-310084 4 0 1 45 *Leigh Disease|*Homozygote|*Mutation|Exome|Pedigree|Mitochondrial Proteins|Magnetic Resonance Imaging|Phenotype|Brain|Peptide Termination Factors|Mitochondria 26 CDKN2AIP 26531822 Nucleic Acids Res. 2015 PMC4666357 10.1093/nar/gkv1069 6 46 1 154 Humans|*RNA, Ribosomal|5'-exoribonuclease|*Exoribonucleases|Pre-rRNA|RNA Processing, Post-Transcriptional|Cell Nucleolus|*Cell Nucleus|Ribosomes|TYRP1 protein, human|*Membrane Glycoproteins|HeLa Cells|Reading Frames|XRN2 protein, human 19 CDKN2AIP 26278998 Mol Oncol 2015 PMC5528716 10.1016/j.molonc.2015.07.003 9 8 1 154 Humans|*Tumor Suppressor Protein p53|Proto-Oncogene Proteins c-mdm2|Apoptosis|*Carcinogenesis|Tumor Suppressor Protein p14ARF|Apoptosis Regulatory Proteins|DNA Damage|DNA-Binding Proteins|Signal Transduction|Cell Line, Tumor|Fibroblasts|Cyclin-Dependent Kinase Inhibitor p16|Protein Binding 19 CDKN2AIP 25881029 BMC Bioinformatics 2015 PMC4349617 10.1186/s12859-015-0463-x 9 15 0 154 Humans|*Prognosis|*Lung Cancer|Carcinoma, Large Cell|Carcinoma, Non-Small-Cell Lung|Adenocarcinoma|Carcinoma, Squamous Cell|Neoplasm Staging|Biomarkers, Tumor|Lymphatic Metastasis|Survival Rate|Retrospective Studies|Epithelial-Mesenchymal Transition|Follow-Up Studies 19 DDRGK1 26678010 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2015 10.1002/ajmg.b.32410 3 0 0 145 Humans|*Parkinson Disease|Genome-Wide Association Study|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Genetic Association Studies|Gene Frequency|Allele|Case-Control Studies|Age-at-Onset|Mainland China 19 DDRGK1 26544067 PLoS Genet. 2015 PMC4636156 10.1371/journal.pgen.1005643 31 58 3 145 Humans|Animals|Adult|E3 Ligase|Ubiquitin|Unfolded Protein Response|Carrier Proteins|Protein Binding|Endoplasmic Reticulum Stress|Hematopoiesis|Ubiquitin-Activating Enzymes|Protein Processing, Post-Translational|Hematopoietic Stem Cells|Transcription Factors|Cell Differentiation|HEK293 Cells|Downregulation|UFM1 protein, human|Proteins|UBA5 protein, human 19 DDRGK1 26019538 Biotechnol. Biotechnol. Equip. 2015 PMC4434134 10.1080/13102818.2014.933501 0 8 0 145 Humans|Male|Female|CpG Islands|DNA Methylation|*Schizophrenia|Epigenesis, Genetic|Bulgaria 19 DDRGK1 25952549 Cell Death Differ. 2015 PMC4816109 10.1038/cdd.2015.51 0 2 6 145 Mice|Animals|*E3 Ligase|*Hematopoiesis|*Hematopoietic Stem Cell|Endoplasmic Reticulum Stress|Proteins|Ubiquitin|Signal Transduction|Unfolded Protein Response|Endoplasmic Reticulum|Homeostasis|Cell Differentiation 19 DISP1 25824302 Mol. Psychiatry 2015 PMC5027902 10.1038/mp.2015.32 8 1 2 24 Humans|*Whole Genome Association Analysis|*Obsessive Compulsive Disorder|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Linkage Disequilibrium|Genotype|Serotonin Reuptake Inhibitors|PCDH10 protein, human|Cadherins 34 DNAI2 26399381 Clin. Exp. Allergy 2015 10.1111/cea.12644 10 15 0 30 *Nasal Polyps|*Interleukin-13|IL17A protein, human|*Interleukin-17|*Sinusitis|Rhinitis|Nasal Mucosa|*Cells, Epithelial|*Cell Differentiation|RNA, Messenger|*Chronic Disease 30 DNAI2 25802884 Mol Genet Genomic Med 2015 PMC4367086 10.1002/mgg3.124 4 2 0 30 Humans|Male|*Jews|Kartagener Syndrome|Axonemal Dyneins|*Mutations|Cilia|Phenotypes|Situs Inversus 30 DRC1 25763715 Mol. Cell. Biochem. 2015 PMC4417035 10.1007/s11010-015-2383-5 10 20 0 38 *Myocytes, Cardiac|*Hydrogen Sulfide|*Homocysteine|Cardiac Hypertrophy|MicroRNAs|NPPA protein, human|Atrial Natriuretic Factor|Hyperhomocysteinemia|Up-Regulation|Myosin Heavy Chain|Gene Expression Regulation 45 FAM111A 26619675 Nippon Rinsho 2015 1 0 0 19 *Syndrome|Kenny-Caffey syndrome, type 2|*Hyperostosis, Cortical, Congenital|Kenny-Caffey syndrome, Type 1|Dwarfism|Hypoparathyroidism-retardation-dysmorphism syndrome|Hypoparathyroidism|Abnormalities, Multiple|Osteochondrodysplasias|Hypocalcemia|Intellectual Disability|Gracile bone dysplasia|Bone Diseases, Developmental|Craniofacial Abnormalities|Growth Disorders|Mutation|Seizures 19 FAM111A 26455281 Pharmacol. Biochem. Behav. 2015 10.1016/j.pbb.2015.10.003 1 0 0 19 Humans|Animals|Rats|*Alcoholism|*Nucleus Accumbens|*Transcriptome|*Ethanol|*Cortex, Prefrontal|*Hippocampus|Alcohol Drinking|*Transcriptome Analysis 19 frem1 26519041 Pediatr. Surg. Int. 2015 10.1007/s00383-015-3824-7 0 4 0 54 Pregnancy|Female|Humans|Rats|Animals|*Hernias, Diaphragmatic, Congenital|*Diaphragm|nitrophen|*Phenyl Ethers|*2,4-Dinitrophenol|*Fetus|Rats, Sprague-Dawley|Lung|*Prenatal Care|Mesoderm|Gene Expression Regulation, Developmental|*Extracellular Matrix|Extracellular Matrix Proteins|FRAS1 protein, human|FREM2 protein, human 58 frem1 26382659 Eur J Pediatr Surg 2015 10.1055/s-0035-1559884 1 0 0 54 Rats|Mice|Animals|*Hernias, Diaphragmatic, Congenital|nitrophen|*Phenyl Ethers|Diaphragm|*2,4-Dinitrophenol|Rats, Sprague-Dawley|Mesenchyme|Lung|*Gene Expression|Fetal Development|Gene Expression Regulation, Developmental|Fetuses|*Extracellular Matrix|Embryonic Development|Disease Models, Animal|Fras1 protein, mouse|Extracellular Matrix Proteins 58 frem1 25736269 Am. J. Med. Genet. A 2015 PMC4522925 10.1002/ajmg.a.36960 7 1 0 54 Humans|Mice|Animals|*Hernias, Diaphragmatic, Congenital|Fibrillin-1|Marfan Syndrome|Ectopia Lentis|Fibrillins|Pedigree|DNA Mutational Analysis|Mutations|Microfilament Proteins|Phenotype|Mutation, Missense|Mutation, Frame Shift|FBN1 protein, human 58 FSCN2 26484279 Genom Data 2015 PMC4583681 10.1016/j.gdata.2015.06.022 0 0 0 24 Animals|Mice|*Mice, Inbred DBA|*Valproic Acid|*L-Methionine|Reproducibility of Results|*Cochlea|Auditory Brain Stem Response|Hearing Loss|*Gene Expression Profiling|*Microarray Analysis|Deafness|Cdh23 protein, mouse|Cadherins 34 FSCN2 26092689 Mamm. Genome 2015 PMC4629822 10.1007/s00335-015-9574-y 4 0 0 24 Humans|Mice|Animals|*Mice, Inbred DBA|fascin|*Quantitative Trait Loci|*Mice, Inbred C57BL|*Microfilament Proteins|*Carrier Proteins|FSCN1 protein, human|Presbycusis|*Deafness|Auditory Brain Stem Response|Allele|Genotype|Genetic Predisposition to Disease|Phenotype|Aging 34 FSCN2 26003529 Hear. Res. 2015 10.1016/j.heares.2015.05.006 7 0 1 24 Mice|Animals|*Mice, Inbred DBA|*C57BL Mice|*Hearing Loss|*Deafness|Cochlea|Spiral Ganglion|Hair Cells, Auditory, Outer|benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone|Amino Acid Chloromethyl Ketones|CASP3 protein, human|Caspase 3|Evoked Potentials, Auditory, Brain Stem|CASP9 protein, human|Caspase 9|Auditory Threshold|Hearing|Stria Vascularis|*Cell Death 34 FSCN2 25803555 Klin Monbl Augenheilkd 2015 10.1055/s-0035-1545702 0 0 0 24 Humans|Peripherins|*Mutations|Macular Degeneration|Fluorescein Angiography|*Genotype-Phenotype Correlation|Electroretinography|Phenotype|Pedigree|Tomography, Optical Coherence|Membrane Proteins|Nerve Tissue Proteins|Membrane Glycoproteins 34 FSCN2 25765874 Exp. Anim. 2015 PMC4547997 10.1538/expanim.14-0110 2 0 0 24 Humans|Animals|Mice|*Mice, Inbred DBA|*Quantitative Trait Loci|*Chromosomes, Human, Pair 5|*Mice, Inbred C57BL|*Hearing|fascin|Microfilament Proteins|*Hearing Tests|Carrier Proteins|Evoked Potentials, Auditory, Brain Stem|FSCN1 protein, human|Genetic Linkage|Auditory Threshold|Cochlea|Chromosome Mapping|Chromosomes, Mammalian|Hearing Loss, High-Frequency|Alleles 34 IFNE 26483316 Infect. Genet. Evol. 2015 10.1016/j.meegid.2015.10.010 1 1 0 58 Humans|Animals|*Macaca mulatta|*Leukocytes, Mononuclear|*CD40 Ligand|*Genetic Markers|Bayes Theorem|*Tuberculosis|Mycobacterium tuberculosis|Tuberculosis, Pulmonary|Monkey Diseases|*Gene Expression|Lungs|Bacterial Load|Host-Pathogen Interactions|Disease Models, Animal|*Leukocytes 19 IMPG2 25681578 Prog Retin Eye Res 2015 10.1016/j.preteyeres.2015.02.001 12 0 2 17 Adult|Humans|*Vitelliform Macular Dystrophy|Fluorescein Angiography|Coherence Tomography, Optical|Retinal Pigment Epithelium|Visual Acuity|Phenotype|Eye Proteins|Electrooculogram|Retrospective Studies|Vision Disorders|Mutation|Single Nucleotide Polymorphism|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1|BEST1 protein, human|Bestrophins 26 IRX2 26633894 PLoS ONE 2015 PMC4669132 10.1371/journal.pone.0144100 9 29 1 141 Humans|*Pancreatic Islets|Homeodomain Proteins|Paired Box Transcription Factors|Glucagon|Cell Differentiation|Insulin|Somatostatin|PPY protein, human|Pancreatic Polypeptide|Basic Helix-Loop-Helix Transcription Factors|Repressor Proteins|Eye Proteins|PAX6 Transcription Factor|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Pancreas|Endocrine Cells|ARX protein, human 71 KIAA0586 26386247 Elife 2015 PMC4641851 10.7554/eLife.08077 19 10 3 86 Humans|Animals|Mice|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Cell Polarity|*Centrosome|Homozygote|Cilia|Mutation|Cell Cycle Proteins|Phenotype|Ciliopathies|Protein Transport|Talpid3 protein, human 27 KIAA0586 26386044 J. Med. Genet. 2015 PMC5517294 10.1136/jmedgenet-2015-103316 24 1 3 86 Animals|Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Chickens|*Cerebellum|*Retina|*Ciliopathy|*Mutations|Phenotype|Cilia|Cell Cycle Proteins|Talpid3 protein, human 27 KIAA0586 26166481 Am. J. Hum. Genet. 2015 PMC4573270 10.1016/j.ajhg.2015.06.003 27 3 4 86 Humans|Animals|Hedgehog Proteins|*Short Rib-Polydactyly Syndrome|*Ciliopathies|*Phenotype|*Mutations|Cilia|Homozygote|Polydactyly|Cell Cycle Proteins|Ribs|Talpid3 protein, human 27 KIAA0586 26096313 Hum. Mutat. 2015 PMC4537327 10.1002/humu.22821 22 2 4 86 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Ciliopathies|Phenotypes|Basal Body|Cilia|Mutation|Cell Cycle Proteins 27 KIAA0586 26026149 Elife 2015 PMC4477441 10.7554/eLife.06602 28 0 3 86 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*RNA, Small Interfering|*Cerebellum|*Retina|Hedgehog Proteins|Ciliopathies|Mutation|Phenotype|Cilium|Cell Cycle Proteins|Exome|Talpid3 protein, human 27 KLHL7 26321861 Mol. Vis. 2015 PMC4539015 0 2 0 90 *Introns|*Whole Exome Sequencing|*3' UTR|*Retinitis Pigmentosa|*Exon|Genes, Dominant|DNA Mutational Analysis|Pedigree|Eye Proteins|Mutation|Polymerase Chain Reaction 30 KLHL7 25584925 Ann Am Thorac Soc 2015 PMC4418314 10.1513/AnnalsATS.201408-380OC 14 0 1 90 Humans|*Genome-Wide Association Study|*Chronic Obstructive Pulmonary Disease|*Hispanics|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Lung|Smoking 30 LMOD2 26586224 Development 2015 PMC4689220 10.1242/dev.129171 11 0 0 42 Mice|Animals|*Tropomodulin|*Actin Cytoskeleton|*Sarcomeres|*Muscle, Skeletal|Tropomyosin|Muscle Proteins|Muscle Contraction|Actins|Myofibril|Actomyosin|Skeletal Muscle Fibers|Isoforms|Protein Binding|Binding Sites|Tmod4 protein, mouse 19 LMOD2 26487682 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4640780 10.1073/pnas.1508273112 30 0 4 42 Mice|Animals|*Cardiomyopathy, Dilated|*Mice, Knockout|*Sarcomeres|*Filaments, Actin|Tropomodulin|Muscle Proteins|Muscle Contraction|Microfilament Proteins|Cardiomyocytes|Myocardium|Cardiomyopathies|Cytoskeletal Proteins|Actin|Muscle, Skeletal 19 LMOD2 26417072 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4611611 10.1073/pnas.1512464112 15 1 1 42 Humans|Animals|*Actin Filament|Actin|Tropomodulin|Tropomyosin|*Muscle Cells|Protein Binding|Muscle Proteins|Amino Acid Sequence|Cell Nucleus|leiomodin 2 protein, human|Microfilament Proteins 19 LMOD3 26586224 Development 2015 PMC4689220 10.1242/dev.129171 11 0 0 46 Mice|Animals|*Tropomodulin|*Actin Cytoskeleton|*Sarcomeres|*Muscle, Skeletal|Tropomyosin|Muscle Proteins|Muscle Contraction|Actins|Myofibril|Actomyosin|Skeletal Muscle Fibers|Isoforms|Protein Binding|Binding Sites|Tmod4 protein, mouse 22 LMOD3 26035871 Dis Model Mech 2015 PMC4457035 10.1242/dmm.019430 14 3 2 46 Mice|Animals|*Myopathies, Nemaline|Sarcomere|Skeletal Muscles|Muscle Proteins|Muscle Atrophy|Disease Models, Animal|leiomodin-3 protein, mouse|Microfilament Proteins 22 LMOD3 25774500 J. Clin. Invest. 2015 PMC4396495 10.1172/JCI80115 24 5 5 46 Mice|Animals|Nemaline Myopathy|Sarcomeres|Actin|Muscle, Skeletal|Muscle Proteins|Transcription Factor SRF|Microfilament Proteins|Muscle Contraction|myocardin|Trans-Activators|Nuclear Proteins|Transcription Factors|Mutation|leiomodin-3 protein, mouse 22 LOXHD1 26561413 PLoS ONE 2015 PMC4641619 10.1371/journal.pone.0142154 16 1 2 9 Humans|Nonsyndromic Deafness|*Deafness|Deafness, Autosomal Recessive 31|Hearing Loss, Sensorineural|Exome|Connexin 26|Connexins|Pedigree|Hearing Loss|Genes, Recessive|Sequencing, Next-Generation|Genetic Testing|Cochlear Implantation|Mutation|Cochlear Implant|Cohort Studies|Turkey|MARVELD2 protein, human 34 MYNN 26354067 Korean J. Intern. Med. 2015 PMC4578038 10.3904/kjim.2015.30.5.719 7 2 1 15 Humans|*Telomere|Republic of Korea|Telomere Homeostasis|Polymorphism, Single Nucleotide|Telomerase|Genome-Wide Association Study|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Genotype|Case-Control Studies 19 MYNN 26040743 J Environ Sci (China) 2015 10.1016/j.jes.2014.10.025 0 0 0 15 Vehicle Emissions|Air Pollutants|Air Movements|Wind|Environmental Monitoring|Models, Theoretical|*Pollutants|Fluid Dynamics|Computer Simulation 19 MYNN 26039576 Epigenetics 2015 PMC4622514 10.1080/15592294.2015.1057672 4 0 0 15 Male|Humans|Mice|Animals|Aged|Female|*Trihalomethane|*Drinking Water|Case-Control Studies|*DNA Methylation|*B-DNA|*Epigenome|Bayes Theorem|Water Treatment|Disinfection|Water Pollutants, Chemical|Environmental Exposure|Spain|Urinary Bladder Neoplasms 19 MYO3A 26166082 Medicine (Baltimore) 2015 PMC4504554 10.1097/MD.0000000000001073 13 1 2 81 50 MYPN 26458567 Int. J. Mol. Med. 2015 PMC4678153 10.3892/ijmm.2015.2361 16 1 2 235 Humans|*Cardiomyopathy, Dilated|*Sequencing, Next-Generation|Genetic Testing|Mutation|Lamin Type A|Pedigree|Heterozygote|Phenotype|Genetic Predisposition to Disease|Sarcomere|Sudden Cardiac Death 32 PASD1 26492414 PLoS ONE 2015 PMC4619595 10.1371/journal.pone.0140483 7 1 1 15 Humans|*Antigens, Neoplasm|CD8-Positive T-Lymphocytes|HLA-A2 Antigen|Epitopes|Immunotherapy|Leukemia, Myeloid, Acute|Flow Cytometry|Peptide Fragments|PASD1 protein, human|Antigens, Nuclear 19 PASD1 26438084 Cancer Immunol. Immunother. 2015 10.1007/s00262-015-1762-9 5 0 1 15 Humans|*Immunotherapy|Vaccines, Peptide|Cancer Vaccines|*Leukemia, Myeloid, Acute|Antigens, Neoplasm|peptide B|*Immunologic Factors|Adjuvants, Immunologic|Peptides 19 PASD1 26327782 Biomark Cancer 2015 PMC4539101 10.4137/BIC.S28378 5 0 1 15 Male|Female|Humans|*Ovarian Cancer|*Testis|*Carcinoma, Ovarian Epithelial|Antigens, Neoplasm|Immunotherapy|Antigens, Nuclear|Biomarkers|PASD1 protein, human 19 PASD1 25936801 Mol. Cell 2015 PMC4458219 10.1016/j.molcel.2015.03.031 14 25 1 15 Humans|Male|*Circadian Clocks|*Testis|ARNTL Transcription Factors|CLOCK Proteins|Circadian Rhythms|Gene Expression Regulation|Transcription, Genetic|Protein Binding|Promoter Regions, Genetic|Activation, Transcriptional|Oncogenesis|PASD1 protein, human|Antigens, Neoplasm|Antigens, Nuclear 19 PDE6H 26558200 Int J Ophthalmol 2015 PMC4630996 10.3980/j.issn.2222-3959.2015.05.10 1 0 0 11 Humans|Achromatopsia 1|*Color Vision Defects|*Mutation, Missense|Cyclic Nucleotide-Gated Cation Channels|DNA Mutational Analysis|Retinal Cone Photoreceptor Cells|Pedigree|Mutation|Electroretinography|Chinese 27 PDE6H 26063662 Hum. Genet. 2015 PMC4529463 10.1007/s00439-015-1571-4 21 8 0 11 Humans|Animals|Mice|Achromatopsia 1|*Color Vision Defects|*Mutation|Retinal Cone Photoreceptor Cells|Cyclic Nucleotide-Gated Cation Channels|Homozygote|Electroretinography|Genes, Recessive|Pedigree|Frameshift Mutation|Color Vision|Photophobia|Retina|Mutation, Missense|Phenotype|Exomes|Asian Continental Ancestry Group|Visual Acuity 27 PDE6H 25757744 Genes Cells 2015 10.1111/gtc.12233 11 2 0 11 Humans|Mice|Animals|*Retinal Photoreceptor|Electroretinography|Retinal Degeneration|Photoreceptor Cell|Retina|Retinal Bipolar Cells|Homeodomain Proteins|Trans-Activators|MEF2 Transcription Factors|Cell Differentiation|Gene Expression Regulation, Developmental|Promoter Regions, Genetic|MEF2D protein, human 27 PDE6H 25739440 J. Biol. Chem. 2015 PMC4400339 10.1074/jbc.M114.611921 6 0 1 11 Humans|Mice|Animals|*Retinal Cone Photoreceptor Cells|*Species Specificity|Phosphodiesterase 6|Retinal Rod Photoreceptor Cells|*Phototransduction|Electroretinography|Retinal Degeneration|*Protein Isoforms|Retina|Transduction, Visual|Signal Transduction|Kinetics 27 PDE6H 25637600 Br J Ophthalmol 2015 10.1136/bjophthalmol-2014-305432 4 0 0 11 Humans|Achromatopsia 1|*Color Vision Defects|Cyclic Nucleotide-Gated Cation Channels|DNA Mutational Analysis|Electroretinography|Retinal Cone Photoreceptor Cells|*Chinese|Mutations|Pedigree|Phenotype|Visual Acuity 27 pdlim3 26455666 Eur J Med Genet 2015 10.1016/j.ejmg.2015.10.001 7 0 0 60 Humans|*Exome|*DNA Copy Number Variations|*High-Throughput Nucleotide Sequencing|*Cardiomyopathy, Hypertrophic|Sequence Analysis, DNA|Carrier Proteins|Cohort Studies 35 pdlim3 26214276 JAMA Neurol 2015 PMC5010776 10.1001/jamaneurol.2015.1424 14 4 0 60 Humans|*Age of Onset|*Alzheimer Disease|*Hispanics|Presenilin-1|Caribbean|*Mutation|*Modifier Gene|*Heterozygote|Genetic Predisposition to Disease|Lod Score|Microsatellite Repeats|PSEN1 protein, human 35 pdlim3 25761764 Sci Rep 2015 PMC4356957 10.1038/srep09042 23 10 6 60 Male|Female|Animals|Mice|Dystrophy, Myotonic|*Isoforms|Alternative Splicing|RNA-Binding Proteins|DNA-Binding Proteins|Muscle, Skeletal|RNA|*Heart|Disease Models, Animal|Capn3 protein, mouse|Calpain|Muscle Proteins|Sorbs2 protein, mouse|Microfilament Proteins 35 PLCL2 25939698 Nat Commun 2015 PMC4422106 10.1038/ncomms8001 49 8 1 21 Humans|Genome-Wide Association Study|*Psoriasis|Genetic Predisposition to Disease|Genetic Loci|Polymorphism, Single Nucleotide|Genotype|NFKBIZ protein, human|Nuclear Proteins|I-kappa B Proteins|Skin|Keratinocytes|PLCL2 protein, human|Intracellular Signaling Peptides and Proteins 19 PLCL2 25880423 Arthritis Res. Ther. 2015 PMC4422604 10.1186/s13075-015-0572-y 8 2 1 21 Humans|*Interferon|Genome-Wide Association Study|interferon regulatory factor-8|*Interferon Regulatory Factors|*Sclerosis, Systemic|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|Haplotypes|Gene Frequency|Multifactorial Inheritance|Phenotype|Case-Control Studies|European Continental Ancestry Group|*Antiviral Agents|PLCL2 protein, human|Intracellular Signaling Peptides and Proteins 19 POU5F1B 25581428 Nat. Genet. 2015 10.1038/ng.3178 101 0 11 44 Humans|Female|*Human Papilloma Virus|*Uterine Cervical Neoplasms|*Papillomavirus Infections|Cervical Intraepithelial Neoplasia|integration, Viral|Alphapapillomavirus|Cervix Uteri|DNA, Viral|Carcinoma, Squamous Cell|*Genomics|RNA, Messenger|KLF12 protein, human|Kruppel-Like Transcription Factors|LEPREL1 protein, human 19 POU5F1B 25562676 Thyroid 2015 10.1089/thy.2014.0431 15 0 2 44 Humans|Japan|*Thyroid Neoplasms|Carcinoma, Papillary|Single Nucleotide Polymorphisms|Thyroid Cancer, Papillary|Genetic Predisposition to Disease|*Chromosome 3|Genotype|Alleles|*Adenoma, Oxyphilic|Thyroid Gland|Genetic Markers|*Chromosome Structures 19 PRCD 26549343 J. Vet. Med. Sci. 2015 PMC4829521 10.1292/jvms.15-0279 5 0 1 11 Dogs|Animals|*Real-Time Polymerase Chain Reaction|*Genotype|Japan|*Cone-Rod Degeneration|*Allele Frequency|*Cone Dystrophy|Breeding|Allele|Dog Diseases|Mutation|*Chronic Kidney Disease-Mineral and Bone Disorder 66 PRCD 26497376 Arch Iran Med 2015 0151811/AIM.009 7 0 0 11 Humans|*Whole Exome Sequencing|Iran|*Retinitis Pigmentosa|Genes, Recessive|Pedigree|Exome|Eye Proteins|Mutation, Missense 66 PRCD 26009980 Vet Ophthalmol 2015 10.1111/vop.12284 2 0 0 11 Dogs|Animals|*Retinal Degeneration|Electroretinography|Pedigree|Dog Diseases|Breeding|Genetic Predisposition to Disease|Atrophy 66 SERPINA9 26225558 PLoS ONE 2015 PMC4520476 10.1371/journal.pone.0133844 5 8 2 6 Humans|Dogs|Animals|*IgA Deficiency|*Genome-Wide Association Study|*Genome|Haplotype|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Breeding|Dog Diseases|IgA|Genes, Regulator|B Cells 19 slamf8 25799045 PLoS ONE 2015 PMC4370648 10.1371/journal.pone.0121968 12 35 2 45 Mice|Animals|*Receptors, Cell Surface|SLAMF1 protein, human|Signaling Lymphocytic Activation Molecule Family Member 1|*Myeloid Cells|Antigens, CD|*Inflammation|NADPH Oxidase|Macrophages|Mice, Knockout|Neutrophils|Reactive Oxygen Species|Signal Transduction|Slamf1 protein, mouse 19 SNX14 26715604 Brain 2015 PMC5841365 10.1093/brain/awv371 24 3 3 37 Humans|Child|Spastic paraplegia 15, autosomal recessive|Hereditary Spastic Paraplegia|Spastic paraplegia 11, autosomal recessive|Absent corpus callosum cataract immunodeficiency|Agenesis of Corpus Callosum|*Autophagy|Lysosomes|Cataract|Mutations|Lysosome-Associated Membrane Glycoproteins|Vesicular Transport Proteins|Neurodevelopmental Disorders|Retinal Degeneration|Nervous System Malformations|Membrane Fusion|SPG11 protein, human|Proteins|TECPR2 protein, human 22 SNX14 26443249 Arch Iran Med 2015 0151810/AIM.007 2 0 0 37 Humans|*Intellectual Disability|*Exome|*Whole Exome Sequencing|*Cerebellar Ataxia|*Genetic Linkage|Genes, Recessive|*Ataxia|Pedigree|Mutations|Family 22 SNX14 26417591 Biomed Res Int 2015 PMC4568325 10.1155/2015/267989 1 5 1 37 Humans|*Alzheimer Disease|*Epitopes|Epitope Mapping|Random Peptide Library|Autoantibodies|Self-Antigens|ELISA|Phages, M13|Cell Surface Display Techniques|Amino Acid Sequence|Immunoglobulin G|Peptides 22 SNX14 26283797 J. Cell Biol. 2015 PMC4539980 10.1083/jcb.201503088 28 14 4 37 Humans|*Lysosome|*Endosomes|Saccharomyces cerevisiae Proteins|Vacuole|Saccharomyces cerevisiae|Endoplasmic Reticulum|Intracellular Membranes|Lipid Droplets|Protein Transport|Lipid Metabolism|Homeostasis|Intermediate Filament Proteins 22 SNX14 25848753 Nat. Genet. 2015 PMC4414867 10.1038/ng.3256 38 1 8 37 Humans|Child|*Autophagosomes|*Lysosome|*Cerebellar Diseases|Sorting Nexin|Autophagy|Endosomes|Cerebellum|Cerebellar Ataxia|Ataxia|*Syndromes|Intellectual Disability|Mutation|Atrophy 22 SNX14 25795301 J. Cell. Sci. 2015 PMC6518326 10.1242/jcs.169581 7 4 2 37 serotonin 6 receptor|*Signal Transduction|Receptors, Serotonin|Protein Kinase A|Cyclic AMP|*Neurons|*Carrier Proteins|GTP-Binding Protein alpha Subunits, Gs|Phosphorylation|Cell Movement|G Protein|Protein Binding|Protein Transport|Amino Acid Sequence 22 SPATA5 26299366 Am. J. Hum. Genet. 2015 PMC4564988 10.1016/j.ajhg.2015.07.014 66 1 8 119 Humans|Male|*Microcephaly|*Intellectual Disability|*Hearing Loss|*Seizures|*Mutations|*Deafness|Brain Diseases|Exome|Hearing Loss, Sensorineural|Pedigree|Sequencing, Whole Exome|Phenotype|*Spermatogenesis|SPATA5 protein, human|ATPases Associated with Diverse Cellular Activities 19 taok2 26367242 Platelets 2015 PMC4933502 10.3109/09537104.2015.1083543 24 9 0 143 Humans|*Platelets|*Transcriptome|*Myocardial Infarction|*Sequencing, RNA|Platelet Activation|Platelet Function Tests|Platelet Aggregation|Megakaryocytes|Transcriptome Analyses|*Base Sequence|ST Segment Elevation Myocardial Infarction|RNA|*Whole Exome Sequencing|CD66 antigens|Antigens, CD 19 TXNDC12 26376864 Hum. Mol. Genet. 2015 PMC4643645 10.1093/hmg/ddv379 22 0 1 67 Humans|*Genome-Wide Association Study|*Obesity|Body Mass Index|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|European Continental Ancestry Group|Genotype|Anthropometry|Cohort Studies|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO 19 TXNDC12 25940440 Oncotarget 2015 PMC4494905 10.18632/oncotarget.3649 5 29 0 67 Mice|Animals|Humans|*Stomach Neoplasms|*Cell Proliferation|Cell Movement|*Cell Cycle|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|PXN protein, human|Paxillin|Prognosis|Signal Transduction|Cell Line, Tumor|Biomarkers, Tumor|Real Time PCR|Mice, Nude|RNA, Small Interfering|*Neoplastic Processes 19 USB1 26546903 Iran J Allergy Asthma Immunol 2015 2 0 0 66 Humans|Poikiloderma with Neutropenia|*Siblings|Turkey|Dental Caries|*Skin Abnormalities|*Neutropenia|Rothmund-Thomson Syndrome|*Mutation|DNA Mutational Analysis|Homozygote|Phenotype|Pedigree|Abnormalities, Multiple|Phosphoric Diester Hydrolases|Skin|*Connective Tissue Diseases 34 wdfy1 26560516 Cancer Res. 2015 PMC4715955 10.1158/0008-5472.CAN-15-1488 17 33 1 79 Humans|*Neuropilin|neuropilin-2, human|*Neuropilin-2|*Endosome|*Protein Transport|Endocytosis|ErbB Receptors|Epidermal Growth Factor|rab GTP-Binding Proteins|Lysosomes|Signal Transduction|Cell Line, Tumor|HeLa Cells|*Cell Movement|EGFR protein, human 19 wdfy1 26208102 PLoS ONE 2015 PMC4514744 10.1371/journal.pone.0133791 9 0 4 79 Female|Mice|Animals|Ahr protein, mouse|AHR protein, human|*Receptors, Aryl Hydrocarbon|*Transcriptome|*Basic Helix-Loop-Helix Transcription Factors|*Hematopoietic Stem Cells|Cell Signaling|*Aging|Cell Movement|Cell Proliferation|Myeloproliferative Disorder|Phenotype 19 wdfy1 25736437 EMBO Rep. 2015 PMC4388604 10.15252/embr.201540145 2 0 1 79 Toll-Like Receptor 3|Adaptor Proteins, Vesicular Transport|Toll-Like Receptors|Toll-Like Receptor 4|Signal Transduction|NF-kappa B|Myeloid Differentiation Factor 88|Interferon Regulatory Factor-3|Lipopolysaccharides|Double-Stranded RNA|Membrane Glycoproteins 19 wdfy1 25736436 EMBO Rep. 2015 PMC4388611 10.15252/embr.201439637 18 13 1 79 *Toll-Like Receptor 3|IRF3 protein, human|Interferon Regulatory Factor 3|*Signal Transduction|Adaptor Proteins, Vesicular Transport|Toll-Like Receptors|Toll-Like Receptor 4|Myeloid Differentiation Factor 88|NF-kappa B|Poly I-C|Innate Immune Responses|Interferon-beta|Cytokines|Adaptor Proteins, Signal Transducing|Lipopolysaccharides 19 WDR11 26199944 Biomed Res Int 2015 PMC4496468 10.1155/2015/649698 2 6 1 50 Humans|Male|Young Adult|Adult|Adolescent|*Kallmann Syndrome|*Receptors, Kisspeptin-1|*Cleft Lip|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|*Mutations|Hypogonadism, Isolated Hypogonadotropic|GNRHR protein, human|Receptors, LHRH|Anosmia|Heterozygote|Extracellular Matrix Proteins|progonadoliberin I|Gonadotropin-Releasing Hormone|Nerve Tissue Proteins|Genetic Screening|Cleft Palate|Palate 36 WDR11 26178983 J. Virol. 2015 PMC4577907 10.1128/JVI.01705-15 3 1 0 50 Chlorocebus aethiops|Humans|Animals|*trans-Golgi Network|*Virus Replication|Herpes Simplex Virus 1|TYRP1 protein, human|*Membrane Glycoproteins|Viral Proteins|Virion|Herpes Simplex Virus Infection|Vero Cells|Cell Line|Cell Nucleus|WDR11 protein, human|Membrane Proteins|Proto-Oncogene Proteins 36 WDR11 26114870 Am. J. Med. Genet. A 2015 10.1002/ajmg.a.37211 5 0 1 50 Male|Humans|*Microcephaly|*Urogenital Abnormalities|Chromosome Deletion|Intellectual Disability|Chromosomal Disorder|Abnormalities, Multiple|Comparative Genomic Hybridization|Phenotype|Psychomotor Disorders|Cryptorchidism|*Chromosome Structures|Genital 36 5HT1 25341312 Rev Med Chir Soc Med Nat Iasi 2014 0 1 0 0 Rats|Animals|Serotonin Receptor Antagonists|Anti-Anxiety Agents|Rats, Wistar|Diazepam|Maze Learning|Anxiety|Piperazines|Disease Models, Animal|Conflict, Psychological|Drinking Behavior 176 5HT1 24670810 Curr Opin Support Palliat Care 2014 PMC4028630 10.1097/SPC.0000000000000044 9 3 1 0 *Serotonin|Triptans|*Migraine|Headache 176 APMAP 25180020 Hum. Mol. Genet. 2014 PMC4275069 10.1093/hmg/ddu449 7 32 1 44 Animals|Humans|Mice|presenilin 1, mouse|Presenilin-1|Amyloid beta-Protein Precursor|Secretase|Alzheimer Disease|Amyloid beta-Peptides|*Brain|Notch Receptors|Membrane Glycoproteins|Hippocampus|HEK293 Cells|*Cell Differentiation|Adipocytes 19 atad5 25404367 J. Immunol. 2014 PMC4272870 10.4049/jimmunol.1401158 6 11 1 147 Mice|Animals|Immunoglobulin Class Switching|*B Cells|Somatic Hypermutation, Immunoglobulin|DNA Breaks, Double-Stranded|Cytidine Deaminase|DNA Repair|ATAD5 protein, human|DNA-Binding Proteins|Recombination, Genetic|Translocation, Genetic|IgG1|ATPases Associated with Diverse Cellular Activities|Cell Division|ATAD5 protein, mouse|Adenosine Triphosphatases 35 atad5 25205120 Mol. Biol. Rep. 2014 10.1007/s11033-014-3705-5 2 0 1 147 Humans|Mice|Animals|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Natural Language Processing|Gene Regulatory Networks|*Text Mining|Gene Expression Regulation, Neoplastic|Signal Transduction|Gene Expression Profiling|Genes, p16|Small Cell Lung Carcinoma|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities|DNA-Binding Proteins|ATAD5 protein, mouse|Adenosine Triphosphatases 35 atad5 24466340 PLoS ONE 2014 PMC3900704 10.1371/journal.pone.0087203 6 47 0 147 Humans|*Histone Deacetylase Inhibitors|Ku Autoantigen|DNA Repair|DNA Breaks, Double-Stranded|Antigens, Nuclear|Rad51 Recombinase|trichostatin A|Hydroxamic Acids|DNA Damage|DNA-Binding Proteins|Nuclear Proteins|Cell Line|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities 35 C12orf65 25519961 Rinsho Shinkeigaku 2014 10.5692/clinicalneurol.54.1012 0 0 0 45 Adult|Humans|Spastic paraplegia type 5A, recessive|Spastic paraplegia 11, autosomal recessive|*Spastic Paraplegia, Hereditary|Phenotype|Mutation|Spastic Paraplegia|Chediak-Higashi Syndrome|Optic Atrophy|Cerebellar Ataxia|Intellectual Disability|SPG11 protein, human|Proteins 26 C12orf65 25519960 Rinsho Shinkeigaku 2014 10.5692/clinicalneurol.54.1009 1 0 0 45 Spastic paraplegia 10, autosomal dominant|Spastic Paraplegia 31, Autosomal Dominant|Spastic paraplegia 3, autosomal dominant|*Spastic Paraplegia, Hereditary|GTP Phosphohydrolases|Paraplegia|Mutation|Membrane Proteins 26 C12orf65 25233460 PLoS Genet. 2014 PMC4169044 10.1371/journal.pgen.1004616 12 3 4 45 Animals|Humans|*Codon, Terminator|*Ribosome|*Protein Biosynthesis|Peptide Chain Termination, Translational|tRNA, peptidyl-|RNA, Transfer, Amino Acyl|*Mitochondria|Ribosomal Protein|Peptide Termination Factors|mRNA|*Mammals|Escherichia coli|ICT1 protein, human 26 C12orf65 24531918 Neurol. Sci. 2014 10.1007/s10072-014-1671-2 1 0 1 45 Humans|Genome-Wide Association Study|*Attention Deficit Disorder with Hyperactivity|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Linkage Disequilibrium 26 C12orf65 24424123 Eur. J. Hum. Genet. 2014 PMC4350599 10.1038/ejhg.2013.284 14 0 1 45 Humans|Child|*Phenotypes|Optic Atrophy|Leigh Disease|Homozygote|Mitochondrial Proteins|Pedigree|Mutation|Peptide Termination Factors|Genotype-Phenotype Correlation|Peripheral Neuropathy|Intellectual Disability|C12orf65 protein, human 26 C12orf65 26380172 J Neuromuscul Dis 2014 PMC4568311 10.3233/JND-140003 7 0 0 45 Behr syndrome|*Optic Atrophy|*Ataxia|*Intellectual Disability|*Spasm|*Hearing Loss|*Mutations|Cerebellar Ataxia|Nystagmus, Pathologic|Pedigree|Peripheral Neuropathy 26 CADPS2 24737869 EMBO Mol Med 2014 PMC4203356 10.1002/emmm.201303235 9 3 1 67 Child|Humans|Animals|Mice|*Intellectual Disability|*Autism Spectrum Disorder|*Maternal Inheritance|Child Development Disorders, Pervasive|*Carrier Proteins|Alleles|Nerve Tissue Proteins|Mutation|Epilepsy|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins 37 CDKN2AIP 25043178 Cell Rep 2014 PMC4152236 10.1016/j.celrep.2014.07.002 24 0 8 154 Cellular Reprogramming|Induced Pluripotent Stem Cells|*Genome|Embryonic Stem Cells|Homeodomain Proteins|Nanog Homeobox Protein|Transcription Factors|Transcriptome Analysis|Cell Differentiation|Fibroblasts 19 CDKN2AIP 24825908 J. Biol. Chem. 2014 PMC4140265 10.1074/jbc.M114.547208 10 2 3 154 Humans|*DNA Damage|*Signal Transduction|Apoptosis|Cellular Senescence|Apoptosis Regulatory Proteins|Tumor Suppressor Protein p53|Cell Proliferation|RNA-Binding Proteins|Cell Line, Tumor 19 CDKN2AIP 24485912 Exp. Cell Res. 2014 10.1016/j.yexcr.2014.01.022 9 2 1 154 Humans|*Transcription Factors|Senescence, Replicative|Tumor Suppressor Protein p53|Apoptosis Regulatory Proteins|Ataxia Telangiectasia Mutated Proteins|DNA Damage|Cell Cycle|Cell Cycle Proteins|Signal Transduction|Apoptosis|RNA-Binding Proteins|Fibroblasts|Cell Line, Tumor|Mitosis 19 CDKN2AIP 24462208 Mol. Cell 2014 10.1016/j.molcel.2014.01.001 16 5 4 154 Humans|Animals|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Exoribonucleases|Carrier Proteins|miRNA|Mutation|NKRF protein, human|Repressor Proteins|XRN2 protein, human|PAXT-1 protein, C elegans 19 CEP120 25361962 Hum. Mol. Genet. 2014 PMC4321448 10.1093/hmg/ddu555 31 1 7 226 Jeune syndrome|*Centrioles|*Ellis-Van Creveld Syndrome|*Ciliopathies|Cilia|Kidney Diseases, Cystic|Phenotypes|Homozygote|Pedigree|Amino Acid Sequence|Mutation|Cell Cycle Proteins 22 CEP120 25251415 PLoS ONE 2014 PMC4176001 10.1371/journal.pone.0107943 15 6 3 226 Mice|Animals|Child|Hedgehog Proteins|*Centrioles|Cilia|*Cell Cycle|Cerebellar Hypoplasia|Cerebellum|Signal Transduction|Cell Division|Cell Cycle Proteins|Neurogenesis|Neuroglia|Neurons|Purkinje Cells|*Cytoplasmic Granules|Developmental Disabilities|Nervous System Malformations 22 DISP1 24968827 Nan Fang Yi Ke Da Xue Xue Bao 2014 0 5 0 24 DUSP1 protein, human|*Dual Specificity Phosphatase 1|*Gene Expression Regulation|*Heat Shock|ELAV Proteins|RNA Processing, Post-Transcriptional|RNA Stability|ELAV-Like Protein 1|RNA, Messenger|Cytoplasm|Cell Nucleus|Protein Binding 34 DISP1 24769501 Bioelectrochemistry 2014 10.1016/j.bioelechem.2014.03.010 1 0 0 24 *Fluorescence|*Density Functional Theory|*Redox|*Riboflavin|Electron Transport|Electron|Proton|Dimethylsulphoxide 34 DNAI2 25232951 PLoS Genet. 2014 PMC4168999 10.1371/journal.pgen.1004577 21 14 3 30 Humans|Adult|Axoneme|Axonemal Dyneins|Kartagener Syndrome|Cilia|Proteins|Exome|Pedigree|Phenotype|Mutation|Cytoplasm|HEATR2 protein, human 30 DNAI2 25186273 Eur. Respir. J. 2014 10.1183/09031936.00052014 0 0 2 30 Humans|Kartagener Syndrome|Cilia|Videomicroscopy|Mutation 30 DRC1 25421206 Mol. Neurobiol. 2014 PMC4442772 10.1007/s12035-014-8927-y 24 5 2 38 Animals|Rats|Parkinson Disease, Mitochondrial|*Parkinson Disease|*Mitochondrial Diseases|Mitochondria|Membrane, Mitochondrial|Electron Transport Complex I|Mitophagy|Protein Kinases|Oxygen Consumption|Brain 45 DRC1 25411337 Mol. Biol. Cell 2014 PMC4294676 10.1091/mbc.E14-09-1367 26 3 1 38 *Axoneme|*Microtubule-Associated Proteins|Flagella|Axonemal Dyneins|*Cytoskeleton|Microtubule|Cilia|Chlamydomonas reinhardtii|Tomography, Electron|Algal Proteins|SERPINE1 protein, human|*Plasminogen Activator Inhibitor 1|Cryoelectron Microscopy|Amino Acid Sequence|Mutation 45 DRC1 24853396 Q J Exp Psychol (Hove) 2014 10.1080/17470218.2014.915332 1 0 0 38 Humans|Reading|Phonetics|Vocabulary|Perceptual Masking|Speech|Reaction Time|Pattern Recognition, Visual|Students 45 FAM111A 24561620 Nat. Cell Biol. 2014 PMC4283098 10.1038/ncb2918 117 3 18 19 Humans|*Chromatin|*Proteomics|Histone H1|Chromatin Assembly Factor-1|Chromatin Assembly and Disassembly|Nucleosomes|DNA Replication|Chromosomal Proteins, Non-Histone|Proliferating Cell Nuclear Antigen|DNA-Binding Proteins|Transcription Factors|Cell Cycle Proteins|Nuclear Proteins|Cell Division|DNA 19 FSCN2 25357075 PLoS ONE 2014 PMC4214712 10.1371/journal.pone.0110299 9 4 0 24 Humans|Mice|Animals|*mRNA|*C57BL Mice|Microphthalmia|Retinitis Pigmentosa|Retinal Degeneration|Hyperopia|Retinal Pigment Epithelium|Homozygote|Retina|*Phototransduction|Photoreceptor Cells|Mutations|Myopia|Membrane Proteins|Serine Proteases|Vision, Ocular|Allele|PRSS56 protein, human 34 FSCN2 24845860 Nat Commun 2014 PMC4311773 10.1038/ncomms4840 12 16 2 24 Chick Embryo|Cats|Animals|*Retinoic Acid|*Chickens|*Hair Cells, Auditory|*Cochlea|Retinoic Acid 4-Hydroxylase|*Signal Transduction|Receptors, Retinoic Acid|Basilar Membrane|Retinal Dehydrogenase|Gene Expression Regulation, Developmental|Aldehyde Oxidoreductases 34 FSCN2 24618324 Invest. Ophthalmol. Vis. Sci. 2014 10.1167/iovs.13-13567 19 0 4 24 Humans|*Whole Exome Sequencing|Thailand|*Retinitis Pigmentosa|DNA Mutational Analysis|Genotype-Phenotype Correlations|Eye Proteins|Pedigree|Exome|Mutation|Phenotype 34 FSCN2 24570207 J. Assoc. Res. Otolaryngol. 2014 PMC4010595 10.1007/s10162-014-0443-2 13 0 4 24 Humans|Mice|Animals|*Genome-Wide Association Study|*Presbycusis|Quantitative Trait Loci|Hearing Loss, Sensorineural|Chromosome Mapping|Phenotype|Chromosomes, Mammalian|Traits, Complex|Genotype|Genetic Predisposition to Disease 34 GSDMC 25149474 Hum. Mol. Genet. 2014 PMC4262497 10.1093/hmg/ddu426 32 2 7 11 Humans|Male|Prostate Cancer|Genetic Loci|*Genomics|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Chromatin|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Genome, Human|USP14 protein, human|Ubiquitin Thiolesterase|FAM84B protein, human 19 GSDMC 25043044 Nature 2014 PMC4767149 10.1038/nature13311 254 19 24 11 Humans|Mice|Animals|PVT1 long-non-coding RNA, human|*RNA, Long Noncoding|myc Gene|Tumorigenesis|Oncogene|Gene Amplification|Gene Expression Regulation, Neoplastic|Gene Dosage|Cell Proliferation|*Genes, Regulator|Cell Line, Tumor 19 HPS3 25277027 Exp. Eye Res. 2014 PMC4252790 10.1016/j.exer.2014.09.010 5 20 1 43 Humans|*Iron|MITF protein, human|Microphthalmia-Associated Transcription Factor|tyrosinase-related protein-1|Oxidoreductases|Tyrosinase|*Transcriptional Activation|Melanosome|TYRP1 protein, human|Melanins|Membrane Glycoproteins|*Upregulation|Gene Expression Regulation|dopachrome isomerase|Intramolecular Oxidoreductases|RNA, Messenger|Pigmentation|ferric ammonium citrate 51 HPS3 25037407 Carbohydr Polym 2014 10.1016/j.carbpol.2014.05.001 1 1 0 43 Spectroscopy, Fourier Transform Infrared|*Osteogenesis|*Fabaceae|*Cell Differentiation|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Osteoblast|Polysaccharides|Drugs, Chinese Herbal|Plant Roots|Uronic Acids 51 HPS3 24766090 Ophthalmic Genet. 2014 PMC4232478 10.3109/13816810.2014.907920 1 0 0 43 Humans|Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells|*Hermanski-Pudlak Syndrome|Membrane Proteins|Carrier Proteins|Mutation|Sequence Deletion|Pedigree|Alternative Splicing 51 IFNE 25372927 PLoS ONE 2014 PMC4221479 10.1371/journal.pone.0112378 13 0 2 58 Swine|Animals|*Type I Interferon|Phylogeny|*Evolution, Molecular|*Antiviral Agents|Genome|Gene Duplication|Pseudogenes|Natural Selection|Amino Acid Sequence|Chromosome Mapping|Repetitive Sequences, Nucleic Acid|Biological Evolution 19 IFNK 25350395 PLoS ONE 2014 PMC4211713 10.1371/journal.pone.0111061 10 3 1 71 Humans|*Polymorphism, Single Nucleotide|Case-Control Studies|*Interferon|*Colorectal Cancer|Genotype|*Colonic Neoplasms|Genetic Predisposition to Disease|Linkage Disequilibrium|Disease-Free Survival|*Antiviral Agents|Proportional Hazards Models|Risk Factors|Survival Analyses|Signal Transduction|Czech Republic 19 IFNK 24742402 Oncotarget 2014 PMC4039222 10.18632/oncotarget.1444 11 3 1 71 Melanoma, Cutaneous Malignant|*Melanoma|Cancer, Skin|*Genes, p16|Receptor, Melanocortin, Type 1|Dysplastic Nevus Syndrome|Cyclin-Dependent Kinase Inhibitor p16|Hair Color|Heterozygote|Genetic Variation|Mutation|Genotype|Pedigree|Genetic Predisposition to Disease|Mutations, Germline 19 IGSF9 24647940 J. Neurosci. 2014 PMC6608096 10.1523/JNEUROSCI.3671-13.2014 12 0 1 96 Mice|Animals|*Synapses|Synaptic Transmission|Cells, Pyramidal|Interneurons|Neural Inhibition|Hippocampus|Nerve Tissue Proteins|Cell Adhesion Molecules 19 IMPG2 25085631 Ophthalmology 2014 10.1016/j.ophtha.2014.06.028 10 0 0 17 *Vitelliform Macular Dystrophy|Bestrophins|*Mutations|Fluorescein Angiography|Coherence Tomography, Optical|Eye Proteins|Chloride Channels|Electroretinography|Visual Acuity|Pedigree|Electrooculography 26 IMPG2 24876279 Invest. Ophthalmol. Vis. Sci. 2014 10.1167/iovs.14-14129 7 1 0 17 Humans|*Retinitis Pigmentosa|Electroretinography|Visual Field Tests|Retina|Visual Acuity|Visual Fields|Tomography, Optical Coherence|Eye Proteins|Mutations|Pedigree|Phenotype 26 KLHL7 24803682 Appl Phys Lett 2014 PMC4000387 10.1063/1.4873676 2 0 1 90 *Proteolysis|*Incidence|Protein Microarrays 30 LMOD3 25431137 J. Cell. Sci. 2014 PMC4294772 10.1242/jcs.152702 17 0 3 46 *Tropomodulin|*Muscle Development|Actin Filament|Sarcomere|Muscle Proteins|Microfilament Proteins|Actins|Muscle, Skeletal|Protein Binding 22 LMOD3 25250574 J. Clin. Invest. 2014 PMC4347224 10.1172/JCI75199 52 0 5 46 Humans|Animals|*Myopathies, Nemaline|*Sarcomeres|Muscle, Skeletal|Muscle Proteins|Microfilament Proteins|Actins|Sequencing, Whole Exome|*Filaments, Actin|Mutations|Phenotypes|Zebrafish|leiomodin 2 protein, human 22 LMOD3 25217591 Nucleic Acids Res. 2014 PMC4191398 10.1093/nar/gku813 32 26 4 46 DUSP6 protein, human|*Dual Specificity Phosphatase 6|Myoblasts, Skeletal|*Muscle, Skeletal|MEF2 Transcription Factors|Cardiomyocytes|Muscle Development|*MAP Kinase Signaling System|Cardiac Muscle|MAPK, p38|Cell Differentiation|Transcriptional Activation|Phosphorylation|Up-Regulation|Downregulation 22 MYNN 24478790 Front Genet 2014 PMC3894567 10.3389/fgene.2013.00310 28 4 3 15 Humans|*Genome-Wide Association Study|*Telomere|*Leukocytes|SNPs|Telomerase|Haplotype|*Genetic Linkage|*Chromosome Structures|Case-Control Studies|Longevity|Genetic Variation|Diabetes Mellitus|MYNN protein, human|Kruppel-Like Transcription Factors 19 MYNN 24455749 J Diabetes Res 2014 PMC3888709 10.1155/2013/970435 14 19 2 15 Humans|*Diabetes Mellitus, Type 2|*Obesity|*Gene Expression Profiling|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|*Microarray Analysis|BAP1 protein, human|Tumor Suppressor Proteins|Ubiquitin Thiolesterase|BCAT1 protein, human|Transaminases|SLC35B4 protein, human|Nucleotide Transport Proteins|POC1B protein, human|Cell Cycle Proteins|MYNN protein, human|Kruppel-Like Transcription Factors 19 MYPN 25541130 J. Am. Coll. Cardiol. 2014 PMC4279060 10.1016/j.jacc.2014.09.071 11 19 0 235 *Cardiomyopathy, Restrictive|Sarcomere|Muscle Proteins|Cardiomyocytes|Myocardium|Ventricular Function, Left|Cardiomyopathies|Phenotype|Mutation, Missense|Mutation|Genetic Predisposition to Disease 32 PDE6H 24675095 Toxicol. Sci. 2014 PMC4031623 10.1093/toxsci/kfu052 4 2 0 11 Animals|*Zebrafish|AHR protein, human|*Receptors, Aryl Hydrocarbon|Zebrafish Proteins|Tetrachlorodibenzo-p-dioxin|Embryo, Nonmammalian|*Hematopoiesis|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|Oligonucleotides, Morpholino|Up-Regulation|*Neurogenesis|Downregulation|Transcriptional Activation 27 PDE6H 24413151 Cell Death Differ. 2014 PMC3978298 10.1038/cdd.2013.191 15 5 3 11 Animals|Humans|*Zebrafish|Photoreceptors, Cone|Retinal Rod Photoreceptor Cells|Retinal Degeneration|Cyclic Nucleotide Phosphodiesterases, Type 6|Zebrafish Proteins|Retina|M-RIP protein, human|*Adaptor Proteins, Signal Transducing|*Cell Death|RIPK3 protein, human|Receptor-Interacting Protein Serine-Threonine Kinases|Mutation|Achromatopsia 1|Achromatopsia|PDE6C protein, human|Eye Proteins|Pde6c protein, zebrafish 27 pdlim3 25473003 Clin. Cancer Res. 2014 10.1158/1078-0432.CCR-13-1711 16 0 1 60 Humans|*Medulloblastoma|*Hedgehog Proteins|Cerebellar Neoplasms|Anilides|Signal Transduction|Pyridines|Antineoplastic Agents|*Molecular Targeted Therapy|Xenograft Model Antitumor Assays 35 pdlim3 25217174 Circ Cardiovasc Genet 2014 10.1161/CIRCGENETICS.114.000537 4 0 0 60 Mice|Animals|Chromosome Mapping|Quantitative Trait Loci|*Heart|Crosses, Genetic|*Genomics|Arrythmia|Phenotype|Gene Expression Profiling|Genetic Predisposition to Disease|*Collagen 35 pdlim3 24491545 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.01.131 2 0 1 60 Animals|Female|Male|*Oryzias|Y Chromosome|Sex Chromosomes|Sex Determination Processes|Gonads|Fish Proteins|Gene Expression Regulation, Developmental|Phenotype|RNA, Messenger|*Brain 35 pdlim3 24462755 Gene 2014 10.1016/j.gene.2014.01.038 0 0 0 60 Animals|Swine|*Actinin|*Muscle, Skeletal|PDLIM4 protein, human|LIM Domain Proteins|Microfilament Proteins|Protein Isoforms|Chromosome Mapping|Amino Acid Sequence|Cloning, Molecular|Cytoskeleton|Muscle Development|DNA-Binding Proteins 35 PLCL2 25163765 Pflugers Arch. 2014 10.1007/s00424-014-1592-1 3 0 1 21 Mice|Animals|Cells, Pyramidal|*Cerebral Cortex|Receptors, GABA A|Synaptic Transmission|Inhibitory Postsynaptic Potentials|Excitatory Postsynaptic Potentials|Somatosensory Cortex|*Cell Communication|Intracellular Signaling Peptides and Proteins|Adaptor Proteins, Signal Transducing|Type C Phospholipases|PRIP-1 protein, mouse|PRIP-1 phospholipase C-related protein, mouse|Carrier Proteins 19 PLCL2 24977159 Biomed Res Int 2014 PMC4054851 10.1155/2014/735292 11 1 1 21 Humans|*Carcinoma, Renal Cell|*Chromosomes, Human, Pair 3|Kidney Neoplasms|DNA Methylation|Von Hippel-Lindau Tumor Suppressor Protein|Genes, Tumor Suppressor|Epigenesis, Genetic|*Epigenetic|Oligonucleotide Array Sequence Analysis|Neoplasm Proteins|DNA, Neoplasm|Genetic Testing|Downregulation|Nucleic Acid Hybridization|LRRC3B protein, human|PLCL2 protein, human|Intracellular Signaling Peptides and Proteins|FGD5 protein, human 19 PLCL2 24916648 Eur. 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Genet. 2014 PMC4326706 10.1038/ejhg.2014.110 12 0 2 21 Humans|*Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|*Myocardial Infarction|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Gene Frequency|Genotype|Coronary Artery Disease|Case-Control Studies|Odds Ratio|Risk Factors|DOT1L protein, human|Histone-Lysine N-Methyltransferase|AP3D1 protein, human|Adaptor Protein Complex 3|Adaptor Protein Complex delta Subunits|PLCL2 protein, human 19 PLCL2 24737248 Pflugers Arch. 2014 10.1007/s00424-014-1511-5 8 0 2 21 Mice|Animals|*Receptors, GABA A|*Mice, Knockout|CABIN1 protein, human|Adaptor Proteins, Signal Transducing|Intracellular Signaling Peptides and Proteins|Calcineurin|Cells, Pyramidal|Protein Transport|GABA-A Receptor Antagonists|Type C Phospholipases|PRIP-1 protein, mouse|PRIP-1 phospholipase C-related protein, mouse|Carrier Proteins 19 POU5F1B 25315430 Cancer Prev Res (Phila) 2014 PMC4256110 10.1158/1940-6207.CAPR-14-0132 4 4 0 44 Humans|Male|*B-DNA|*DNA Methylation|Reproducibility of Results|Genetic Susceptibility|Single Nucleotide Polymorphisms|Prostate Cancer|DNA, Neoplasm|European Continental Ancestry Group|Genotype|Case-Control Studies|Risk Factors|*Chromosome Structures 19 POU5F1B 24581739 Am. J. Hum. Genet. 2014 PMC3951923 10.1016/j.ajhg.2014.01.019 14 0 0 44 Humans|Male|*Embryonic Stem Cell|POU5F1 protein, human|Transcription Factor Oct-4|*Prostatic Neoplasms|*Genes, Homeobox|Transcription Factors|Cell Differentiation|Regulatory Elements, Transcriptional|Genotype 19 PRCD 24992209 Exp. Eye Res. 2014 10.1016/j.exer.2014.06.017 3 1 0 11 Humans|Dogs|Animals|Retinitis Pigmentosa|*Cone-Rod Degeneration|*Golgi Apparatus|*Cone Dystrophy|Eye Proteins|Retinal Degeneration|Mutation|Pedigree|Macular dystrophy, concentric annular|Macular Degeneration|Amino Acid Sequence|Protein Stability|Missense Mutation 66 PRCD 24581223 BMC Genomics 2014 PMC4029133 10.1186/1471-2164-15-172 18 3 5 11 Dogs|Animals|*Retinal Degeneration|*miRNAs|*Retina|Photoreceptor Cell|Gene Expression Profiling|Mutation|Dog Diseases|Disease Models, Animal 66 PRCD 26401321 Canine Genet Epidemiol 2014 PMC4574394 10.1186/2052-6687-1-4 10 6 1 11 Dogs|Animals|*Retinal Degeneration|Retinitis Pigmentosa|Mutation|Genome-Wide Association Study|Frameshift Mutation|Dog Diseases|Phenotype|Breeding|Atrophy 66 s100a5 25411495 J. Neurosci. 2014 PMC4236398 10.1523/JNEUROSCI.3625-14.2014 18 0 1 15 Humans|Mice|Animals|*Receptors, Odorant|muscone|*Eugenol|Sensory Neurons, Olfactory|*Cycloparaffins|Smell|Odorants|Ligands|musk|Fatty Acids, Monounsaturated|Protein Binding|Kentucky|S100A5 protein, human|S100 Proteins 39 s100a5 24748648 Mol. Cell Proteomics 2014 PMC4083118 10.1074/mcp.M113.035378 7 0 1 15 Mice|Animals|*Olfactory Receptor Neurons|*Receptors, Odorant|*Proteome|*Cilia|Olfaction|Na(+)-Ca(2+) Exchanger|Plasma Membrane|Calcium|Signal Transduction|Annexins|Annexin A2|Chromatography, Liquid 39 s100a5 24692514 Chem. Senses 2014 PMC4025512 10.1093/chemse/bju015 7 0 1 15 Mice|Animals|*Olfactory Receptor Neurons|Receptor, Odorant|Odorants|Smell|*Gene Activation|mRNA|Nasal Cavity|Kirrel3 protein, mouse|Membrane Proteins|Rasgrp4 protein, mouse|ras Guanine Nucleotide Exchange Factors|Ptprn protein, mouse|Receptor-Like Protein Tyrosine Phosphatases, Class 8 39 SERPINA9 25203428 Appl. Immunohistochem. Mol. Morphol. 2014 10.1097/PAI.0000000000000107 1 0 0 6 Humans|*Germinal Center|LIM Domain Proteins|Lymphomas, Follicular|Immunohistochemistry|Neoplasm Proteins|B-Lymphocytes|Biomarkers, Tumor|Lymphoma, B-Cell, Marginal Zone|Intracellular Signaling Peptides and Proteins|Burkitt Lymphoma|Adaptor Proteins, Signal Transducing|Proto-Oncogene Proteins|Lymphoma, Large B-Cell, Diffuse|Hodgkin Lymphoma|Microfilament Proteins|Leukemia|Lymph Nodes|LMO2 protein, human 19 slamf8 25219326 Am. J. Transplant. 2014 10.1111/ajt.12946 25 0 2 45 Humans|*Kidney Transplantation|CTLA4 protein, human|*CTLA-4 Antigen|*T-Lymphocytes|*Ligands|Graft Rejection|Killer Cells, Natural|Antibodies|Biopsies|Macrophages 19 slamf8 24795728 Front Immunol 2014 PMC4005954 10.3389/fimmu.2014.00186 16 21 2 45 Mice|Animals|*SLAMF Receptors|CD8-Positive T-Lymphocytes|*BALB C Mice|SH2D1A protein, human|Signaling Lymphocytic Activation Molecule Associated Protein|Natural Killer T-Cells|*Cell Differentiation|Lymphocyte Activation|B-Lymphocytes|Mice, Inbred C57BL|Thymocytes|Promyelocytic Leukemia Zinc Finger Protein|Slamf6 protein, mouse 19 SMPX 24936977 PLoS ONE 2014 PMC4060999 10.1371/journal.pone.0099232 2 4 0 17 Rats|Mice|Animals|*Skeletal Muscle Fibers|*Muscle, Skeletal|Muscle Proteins|Sarcomeres|Gene Expression Regulation|Cell Nucleus|Cell Differentiation|Transcription Factor|Transcriptional Activation 41 SMPX 24687041 Am J Audiol 2014 10.1044/2014_AJA-13-0040 4 0 1 17 Canada|*Hearing Loss|*Deafness|Progressive hearing loss stapes fixation|Hearing Loss, Sensorineural|Hearing Loss, Conductive|Genetic Diseases, X-Linked|*Genes, X-Linked|*Mutations|POU Domain Factors|Phenotype|Pedigree 41 SNX14 25439728 Am. J. Hum. Genet. 2014 PMC4225633 10.1016/j.ajhg.2014.10.007 31 2 4 37 Humans|*Cerebellar Ataxia|*Intellectual Disability|*Mutations|Cerebellar Diseases|Cerebellum|*Syndrome|Homozygote|Pedigree|Microcephaly|Sequencing, Whole Exome|Sorting Nexins|Phenotype|Sequence Analysis|Mutation, Nonsense 22 SNX14 25148684 J. Biol. Chem. 2014 PMC4192506 10.1074/jbc.M114.595959 12 2 2 37 Animals|*Sorting Nexins|*Phosphatidylinositols|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|*Signal Transduction|*G Protein|Protein Binding|Endosomes|Binding Sites|Protein Transport|Amino Acid Sequence|Protein Domain 22 SNX14 24859318 PLoS ONE 2014 PMC4032282 10.1371/journal.pone.0098383 14 0 3 37 Animals|Mice|*Synaptic Transmission|Genomic Imprinting|Neurons|Visual Cortex|Sorting Nexins|*Brain|*Nervous System Physiological Phenomena|Laser Capture Microdissection|Snx14 protein, mouse 22 SPATA5 25262113 BMC Genomics 2014 PMC4190347 10.1186/1471-2164-15-821 5 22 1 119 *Endocardial Cushions|*Limb Buds|TWIST1 protein, human|*Twist-Related Protein 1|*Nuclear Proteins|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|Protein Binding|RNA, Small Interfering|*Nerve Sheath Neoplasms 19 taok2 25309321 Front Cell Neurosci 2014 PMC4161164 10.3389/fncel.2014.00276 47 23 4 143 Humans|Child|*Autism Spectrum Disorder|gephyrin|*Carrier Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Genetic Predisposition to Disease|Mutations|Membrane Proteins|Nerve Tissue Proteins|Child Development Disorders, Pervasive|Synapses|Synaptic Receptors|Cadherins 19 TGM6 25253745 Neurology 2014 10.1212/WNL.0000000000000909 12 0 3 55 Humans|*Spinocerebellar Ataxias|Mutations|Pedigree|Asian Continental Ancestry Group|Transglutaminases|Cohort Studies 22 TGM6 24755948 Eur. 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Genet. 2014 PMC4297898 10.1038/ejhg.2014.67 6 0 0 55 Humans|*Pedigree|Familial Acute Myeloid Leukemia with Mutated Cebpa|*Leukemia, Myeloid, Acute|*Sequencing, Next-Generation|*Mutation|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|GATA2 protein, human|GATA2 Transcription Factor|*Chinese|Genetic Linkage|Genetic Predisposition to Disease|Missense Mutation|Phenotype|*Genetic Techniques|Cloning, Molecular 22 TSPEAR 25268383 PLoS ONE 2014 PMC4182092 10.1371/journal.pone.0107101 19 3 2 2 Sheep|Animals|Humans|*Wool|*Genome-Wide Association Study|*Sheep, Domestic|*Phenotype|Genotype|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Breeding|*Chinese|GPRC5A protein, human|Receptors, G-Protein-Coupled|TSPEAR protein, human|Proteins|TPTE2 protein, human|Dual-Specificity Phosphatases 19 wdfy1 24659297 Neurogenetics 2014 PMC3994287 10.1007/s10048-014-0397-x 19 12 2 79 Animals|Mice|TIA1 protein, human|*T-Cell Intracellular Antigen-1|Motor Neuron Disease, Amyotrophic Lateral Sclerosis|Messenger RNA|DNA-Binding Proteins|Binding Protein|Muscular Atrophy, Spinal|Spinal Cord|Cytoplasm|Transcriptome Profiling|Cell Nucleus|Oligonucleotide Microarrays|Mice, Knockout|Lipids|Nerve Tissue 19 WDR11 25198678 J. Proteome Res. 2014 PMC4227559 10.1021/pr500656z 7 7 1 50 Animals|Mice|*Dysbindin|*Synaptosomes|*Proteome|Dystrophin-Associated Proteins|Synapses|Carrier Proteins|Nerve Tissue Proteins|Lectins|Isoforms|Schizophrenia|Neuroplasticity|Mice, Transgenic|Brain|Dtnbp1 protein, mouse 36 WDR11 25140149 Front Aging Neurosci 2014 PMC4121544 10.3389/fnagi.2014.00183 8 3 0 50 Humans|tau Proteins|Amyloid beta-Peptides|Alzheimer Disease|Peptide Fragments|Atrophy|Biomarkers|Brain|Polymorphism, Single Nucleotide|Genotype|*DNA Mutational Analysis|Disease Progression 36 WDR11 25071724 Front Endocrinol (Lausanne) 2014 PMC4088923 10.3389/fendo.2014.00109 26 17 3 50 Humans|Male|Female|Animals|*Smell|Kallmann Syndrome|Idiopathic Hypogonadotropic Hypogonadism|Hypogonadism|GNRHR protein, human|Receptors, LHRH|progonadoliberin I|Gonadotropin Releasing Hormone|FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|KISS1 protein, human|Kisspeptins|Olfaction Disorders|Mutations|Hypothalamus|Gonadotropin|*Reproduction|Pituitary Gland 36 5HT1 24063986 Life Sci. 2013 10.1016/j.lfs.2013.09.012 3 3 1 0 Rats|Animals|*Electroacupuncture|*Pain Management|*Pain|Naloxone|Methysergide|Narcotic Antagonists|Pain Measurement|*Pretectal Region|Rats, Wistar|Nociceptors|*Agnosia 176 5HT1 23953048 Kardiologiia 2013 0 0 0 0 Pregnancy|Female|Humans|*Hypertensive Encephalopathy|Drugs, Anti-Hypertensive|Hypertension, Malignant|Emergencies|Acute Disease|Pre-Eclampsia|*Ambulatory Care Facilities|urapidil|Piperazines 176 5HT1 23659057 Ross Fiziol Zh Im I M Sechenova 2013 0 3 0 0 *Calcium Channels|*Calcium|*Receptor, Serotonin, 5-HT1B|*Hippocampus|Neurons|Patch-Clamp Techniques|Membrane Potentials|Calcium Signaling|Presynaptic Receptors|Cells, Cultured 176 APMAP 24256100 BMC Cell Biol. 2013 PMC4225516 10.1186/1471-2121-14-50 4 3 1 44 Mice|Animals|Male|*Acrosome|*Sperm Tail|Spermatids|*Y Chromosome|Sperm|Spermatogenesis|Testis|Amino Acid Sequence|TYRP1 protein, human|Membrane Glycoproteins 19 APMAP 23545286 Dev. 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Immunol. 2013 10.1016/j.dci.2013.03.014 21 0 3 44 Animals|*Drosophila|Drosophila Proteins|Drosophila melanogaster|*Blood Coagulation|Hemolymph|Larva|Hemostasis|Clotting Factors|Immunity, Innate|Proteomics|*Mammals 19 C12orf65 24284555 J Neuroophthalmol 2013 10.1097/WNO.0000000000000076 8 0 2 45 Humans|Leigh Syndrome|*Optic Atrophy|*Mutations|Mitochondrial Proteins|DNA, Mitochondrial|Pedigree|Mitochondria|Brain|*Syndrome|Magnetic Resonance Imaging|C12orf65 protein, human|Peptide Termination Factors 26 CADPS2 24287856 Int J Environ Res Public Health 2013 PMC3881117 10.3390/ijerph10126335 3 11 1 67 Mice|Animals|Child|*Alternative Splicing|*Autism Spectrum Disorder|Genome-Wide Association Study|*DNA Copy Number Variations|*Mutations|Autism|*Cryopyrin-Associated Periodic Syndromes|Child Development Disorders, Pervasive|Calcium-Binding Proteins|Phenotypes|Nerve Tissue Proteins|Vesicular Transport Proteins|Disease Models, Animal|CAPS2 protein, mouse 37 CADPS2 23977060 PLoS ONE 2013 PMC3747221 10.1371/journal.pone.0071509 28 2 5 67 Swine|Humans|Male|Animals|*Genome-Wide Association Study|*Feeding Behavior|Quantitative Trait Loci|*Obesity|Chromosome Mapping|Genotype|Linkage Disequilibrium|Sus scrofa|Phenotype|SNPs|Eating|Quantitative Trait, Heritable|Haplotypes|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins|MSI2 protein, human|RNA-Binding Proteins 37 CADPS2 23715297 Transl Psychiatry 2013 PMC3669925 10.1038/tp.2013.38 9 0 2 67 Child|Humans|Male|*Haplotypes|*Autism Spectrum Disorder|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Alleles|DNA Copy Number Variations|Genetic Markers|Child Development Disorders, Pervasive|Multifactorial Inheritance|Genetic Linkage|Phenotype|DNA Mutational Analysis|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins 37 CADPS2 23634235 Oxid Med Cell Longev 2013 PMC3619550 10.1155/2013/454328 3 12 1 67 Humans|plastochromanol 8|*Diploidy|*Chromans|*Vitamin E|*Fibroblasts|Cell Senescence|Tocotrienol|Apoptosis|Cells, Cultured|Cell Proliferation|*Gene Expression|Down-Regulation|*Microarray Analysis|Genes, Regulator|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins|COG6 protein, human 37 CADPS2 23615300 Exp. Anim. 2013 10.1538/expanim.62.71 9 0 2 67 Mice|Animals|Child|*Autistic Disorder|*Autism Spectrum Disorder|Genome-Wide Association Study|Mice, Knockout|Child Development Disorders, Pervasive|Phenotypes|Nerve Tissue Proteins|Disease Models, Animal|Synaptic Transmission|Behavior, Animal|Genetic Predisposition to Disease|Brain|Carrier Proteins 37 CADPS2 23482763 Anticancer Res. 2013 1 2 0 67 Humans|*Tumor Suppressor Protein p53|Tumor Suppressor Protein p14ARF|Cyclin-Dependent Kinase Inhibitor p16|Genes, p53|DNA, Neoplasm|Mutation|RNA, Neoplasm|DNA Methylation|Tumors|Carrier Proteins|Point Mutation|RNA, Messenger|CADPS2 protein, human|Calcium-Binding Proteins|Vesicular Transport Proteins 37 CDKN2AIP 24127483 J. Exp. Med. 2013 PMC3804949 10.1084/jem.20131448 58 3 1 154 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Lymphoma, Large B-Cell, Diffuse|*Cell Transformation, Neoplastic|Disease Progression 19 CEP120 23857771 J. Cell Biol. 2013 PMC3718976 10.1083/jcb.201212060 40 13 11 226 Humans|*Centrioles|*Cell Cycle|Microtubule-Associated Proteins|Cell Cycle Proteins|Microtubule|Phosphoproteins|Mitosis|HeLa Cells|Protein Binding|HEK293 Cells|RNA, Small Interfering|CEP120 protein, human 22 CEP120 23810536 Curr. Biol. 2013 10.1016/j.cub.2013.06.002 62 6 10 226 Humans|*Centrioles|*Cell Cycle|Centrosomes|Cell Cycle Proteins|Microtubule|Microtubule-Associated Proteins|Intracellular Signaling Peptides and Proteins|Cilia|HeLa Cells|Protein Binding|HEK293 Cells|RNA, Small Interfering|Genome Instability|CEP120 protein, human 22 CEP120 23456457 Protoplasma 2013 10.1007/s00709-013-0488-9 24 0 5 226 *Centrosome|Centriole|CNTRL protein, human|Cell Cycle Proteins|CEP350 protein, human|Nuclear Proteins|Chromosomal Proteins, Non-Histone|Cell Cycle|TYRP1 protein, human|*Membrane Glycoproteins|Microtubule Proteins 22 DDRGK1 23675531 PLoS ONE 2013 PMC3651127 10.1371/journal.pone.0064231 13 32 1 145 I-kappa B Proteins|NF-KappaB Inhibitor alpha|NF-kappa B|I-kappa B Kinase|Transcription Factor RelA|Phosphorylation|Signal Transduction|Enzyme Activation|Cell Proliferation|Cyclin D1|Tumor Necrosis Factor-alpha|Cell Line, Tumor|Cell Nucleus 19 DISP1 23542665 Eur J Med Genet 2013 10.1016/j.ejmg.2013.03.007 5 0 0 24 Child|Humans|*Haploinsufficiency|Chromosome Deletion|Chromosome Disorders|Abnormalities, Multiple|Comparative Genomic Hybridization|Developmental Disabilities|Syndrome|Phenotype|In Situ Hybridization, Fluorescence|Seizures 34 DNAI2 24203976 J. Med. Genet. 2013 PMC3888613 10.1136/jmedgenet-2013-101938 29 5 4 30 Humans|Male|*Axoneme|*Exome|*Dyneins|Sperm Motility|Kartagener Syndrome|Cilia|*Mutations|*Sequencing, Whole Genome|Sequencing, Next-Generation|Pedigree|Phenotype 30 DNAI2 23936072 PLoS ONE 2013 PMC3720563 10.1371/journal.pone.0069670 9 17 1 30 Humans|*Respiratory Syncytial Virus Infections|Roflumilast|Hydrogen Peroxide|roflumilast N-oxide|*Aminopyridines|*Benzamides|*Epithelial Cells|Respiratory Syncytial Viruses|*Cyclopropanes|*Cell Differentiation|Phosphodiesterase 4 Inhibitors|Mucin 5AC|Bronchi|Respiratory Mucosa|Goblet Cells|IL 13|Cells, Cultured|Virus Replication 30 DRC1 23354437 Nat. Genet. 2013 PMC3818796 10.1038/ng.2533 77 7 6 38 Male|Humans|*Cilia|*Axonemes|*Microtubule-Associated Proteins|Axonemal Dyneins|Kartagener Syndrome|Flagella|Chlamydomonas reinhardtii|Sperm Flagellum|Mutations|Phenotype|SERPINE1 protein, human|*Plasminogen Activator Inhibitor 1|*Cytoskeleton 45 FAM111A 23996431 J. Bone Miner. Res. 2013 10.1002/jbmr.2091 8 1 1 19 Humans|Kenny-Caffey syndrome, Type 1|*Hyperostosis, Cortical, Congenital|Kenny-Caffey syndrome, type 2|*Dwarfism|*Hypocalcemia|Hypoparathyroidism|Mental Retardation|Heterozygote|Abnormalities, Multiple|Parathyroid Hormone|Mutation|Syndrome|Missense Mutation|Diabetes Mellitus, Type 2|TBCE protein, human|Molecular Chaperones|FAM111A protein, human|Receptors, Virus 19 FAM111A 23684011 Am. J. Hum. Genet. 2013 PMC3675238 10.1016/j.ajhg.2013.04.020 18 0 2 19 Humans|Kenny-Caffey syndrome, Type 1|Hyperostosis, Cortical, Congenital|*Hypoparathyroidism|Dwarfism|Gracile bone dysplasia|Bone Diseases, Developmental|Hypocalcemia|*Mutations|Heterozygote|Craniofacial Abnormalities|Abnormalities, Multiple|FAM111A protein, human|Receptors, Virus 19 FAM111A 23390342 Bioinformation 2013 PMC3563414 10.6026/97320630009037 8 13 1 19 Humans|Animals|Mice|Diabetes Mellitus, Type 2|*Cell Survival|*Mice, Inbred C57BL|*Insulin-Secreting Cells|Insulin Resistance|B-insulin|Insulin|Obesity|Biotin|*Metabolic Stress 19 FSCN2 24319057 Mol. Cell Proteomics 2013 PMC3916657 10.1074/mcp.M113.033704 15 0 4 24 Animals|*Stereocilia|*Actins|Hair Cells, Auditory|Cochlea|Microfilament Proteins|Cilia|Vestibule, Labyrinth|Chickens|Animals, Newborn|Epithelium 34 IFNE 24055696 Hum. Immunol. 2013 10.1016/j.humimm.2013.09.004 2 0 0 58 Humans|*Alleles|*Interferon|*Risk Factors|*Cerebral Hemorrhage|Allele Frequency|Genotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Stroke|*Antiviral Agents|*Codon, Nonsense|Asian Continental Ancestry Group|Case-Control Studies 19 IFNE 23964570 J. Interferon Cytokine Res. 2013 PMC3868301 10.1089/jir.2013.0037 6 0 0 58 Animals|Dogs|Interferons|Antiviral Agents|Cloning, Molecular|Gene Expression|Recombinant Proteins|MDCK Cell|Escherichia coli|Genome|Phylogeny 19 IFNE 23802172 Immunol. Invest. 2013 10.3109/08820139.2013.804836 2 0 0 58 Humans|Child|*Vitiligo|*Interferon|Republic of Korea|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Gene Frequency|Genotype|*Hypopigmentation|*Antiviral Agents|Case-Control Study|*Codon, Nonsense|Odds Ratios|Logistic Models 19 IFNK 23964570 J. Interferon Cytokine Res. 2013 PMC3868301 10.1089/jir.2013.0037 6 0 0 71 Animals|Dogs|Interferons|Antiviral Agents|Cloning, Molecular|Gene Expression|Recombinant Proteins|MDCK Cell|Escherichia coli|Genome|Phylogeny 19 IFNK 23376709 J. Urol. 2013 10.1016/j.juro.2013.01.096 18 1 4 71 Male|Humans|*Genome-Wide Association Study|*Polymorphism, Single Nucleotide|*Prostate Cancer|Brachytherapy|Genetic Predisposition to Disease|Iodine Radioisotopes 19 IGSF9 23417431 Neurochem. Res. 2013 10.1007/s11064-013-0999-y 8 0 0 96 Animals|tutl protein, Drosophila|Nerve Tissue Proteins|Drosophila Proteins|Immunoglobulins|TYRP1 protein, human|*Membrane Glycoproteins|Membrane Proteins|Drosophila|Neural Cell Adhesion Molecule|Neurites|Neurons|Cell Adhesion Molecules|Nervous System|Isoforms|Gene Expression Regulation, Developmental 19 IMPG2 24339724 Mol. Vis. 2013 PMC3857159 16 0 0 17 *Retinitis Pigmentosa|*Homozygote|Genes, Recessive|Eye Proteins|Pedigree|DNA Mutational Analysis|Mutation|Electroretinography|Polymorphism, Single Nucleotide 26 PASD1 23882161 Cancer Immun. 2013 PMC3718735 7 2 0 15 Humans|Male|Mice|Animals|*Testis|*CD8-Positive T-Lymphocytes|HLA-A*02:01 antigen|HLA-A2 Antigen|T-Lymphocytes, Cytotoxic|*Peptides|CD4-Positive T-Lymphocytes|Antigens, Neoplasm|Epitopes|Dendritic Cells|Interferon-gamma|PASD1 protein, human|Antigens, Nuclear 19 PCDH12 23896029 Placenta 2013 10.1016/j.placenta.2013.06.310 8 0 0 30 Male|Humans|Female|Pregnancy|Animals|*Glucocorticoids|*Glycogen|*Placenta|Placentation|Dexamethasone|Fetal Growth|Fetus|*Spine|Gene Expression Regulation, Developmental|Murinae 27 PCDH12 23277015 Front Biosci (Elite Ed) 2013 PMC4046710 10.2741/e641 5 15 2 30 Female|Pregnancy|Rats|Animals|*Trophoblasts|*Cell Differentiation|Placental Development|Pregnancy Proteins|Placenta|Giant Cells|Stem Cell|Gene Expression Regulation, Developmental|TYRP1 protein, human|*Membrane Glycoproteins|In Situ Hybridization 27 PDE6H 24069333 PLoS ONE 2013 PMC3775801 10.1371/journal.pone.0074712 12 0 3 11 Humans|Photoreceptors, Cone|Rod Photoreceptors|Retina|Retinal Degeneration|Rhodopsin|Color Vision|Ophthalmoscopy|Retinal Pigment Epithelium|HIV Infections 27 PLCL2 23822953 Biochem. J. 2013 PMC3893797 10.1042/BJ20121750 28 23 4 21 *Phosphorylation|*Receptor, Collagen|Proteomics|LTK protein, human|Receptor Protein-Tyrosine Kinases|Receptors, Mitogen|Receptors, Discoidin Domain|Signal Transduction|PTPN11 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 11|*Lung Cancer|Protein Binding|SHC1 protein, human|Src Homology 2 Domain-Containing, Transforming Protein 1|Binding Sites|Collagen|Cell Movement|Base Sequence 19 PLCL2 23639135 Mol Pain 2013 PMC3651726 10.1186/1744-8069-9-23 3 3 0 21 Mice|Animals|*Phospholipase C|*Pain, Neuropathic|GABA A Receptor|Hyperalgesias|Mice, Knockout|Spinal Cord|Binding Protein|Intracellular Signaling Peptides and Proteins|Adaptor Proteins, Signal Transducing|PRIP-1 protein, mouse|PRIP-1 phospholipase C-related protein, mouse 19 POU5F1B 24362523 Oncogene 2013 10.1038/onc.2013.547 45 0 8 44 Humans|*Pseudogenes|*Stomach Neoplasms|Cell Proliferation|*Transcription Factors|Upregulation|Octamer Transcription Factor-3|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Transformation, Neoplastic|Xenografts|*Phenotype 19 PRCD 23805042 Mol. Vis. 2013 PMC3692407 5 1 0 11 Humans|Dogs|Animals|*Retinitis Pigmentosa|*Cone-Rod Degeneration|*Cone Dystrophy|Genes, Recessive|Eye Proteins|Homozygote|Pedigree|Mutations|Retinal Degeneration|Electroretinography|Fundus Oculi|Amino Acid Sequence|Phenotype 66 PRCD 23727965 J Health Care Poor Underserved 2013 10.1353/hpu.2013.0104 4 0 0 11 *Community-Based Participatory Research|*Obesity|Community-Institutional Relations|Health Promotion|*Collaborative Learning|Research Design 66 PRCD 23672200 J. Proteome Res. 2013 PMC3771658 10.1021/pr4003678 19 0 2 11 *Retinal Degeneration|*Proteomics|Photoreceptor Cells, Vertebrate|Eye Proteins|Photoreceptor Cells|Membrane Proteins|Proteome|Mutations|Mass Spectrometry 66 SERPINA9 24319541 Int J Mol Epidemiol Genet 2013 PMC3852645 0 0 0 6 *Carotid Atherosclerosis|*Carotid Artery|*Atherosclerosis|*Carotid Artery, Common|Plaques, Atherosclerotic|Stroke|Risk Factors|Carotid Artery Plaque|Contrast Media|SNPs|Lipids|Linear Regression|Magnetic Resonance Imaging 19 SERPINA9 24117687 Histopathology 2013 10.1111/his.12223 9 0 2 6 Humans|*Immunohistochemistry|*Prognosis|*Lymphoma, Large B-Cell, Diffuse|Proto-Oncogene Proteins c-bcl-6|Vincristine|Rituximab|Antibodies, Monoclonal, Murine-Derived|Cyclophosphamide|*Immunotherapy|Antineoplastic Combined Chemotherapy Protocols|Proto-Oncogene Proteins c-bcl-2|Biomarkers, Tumor|Prednisone|DNA-Binding Proteins|Kaplan-Meier Estimate|Interferon Regulatory Factors|Disease-Free Survival|Neprilysin 19 slamf8 23493347 Clin. Cancer Res. 2013 10.1158/1078-0432.CCR-12-1000 36 0 3 45 Humans|*Aromatase Inhibitors|*Postmenopause|Receptors, Estrogen|Anastrozole|Letrozole|Antineoplastic Agents, Hormonal|Nitriles|Ki-67 Antigen|Triazoles|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Drug Resistance, Neoplasm|Oligonucleotide Array Sequence Analysis|Estrogens|*Breast Cancer 19 SMPX 23675446 PLoS ONE 2013 PMC3651093 10.1371/journal.pone.0062959 8 19 1 17 Animals|Mice|*Signal Transduction|Neural Tube|Neural Stem Cell|Cell Differentiation|Receptors, Notch|Neurulation|Cell Polarity|Embryonic Stem Cells|Neurogenesis|Morphogenesis|Cells, Cultured|*Nervous System 41 TGM6 24275721 Curr. Opin. Neurol. 2013 10.1097/WCO.0000000000000053 13 1 4 55 *Dizziness|*Vertigo|*Vestibular Diseases|*Cerebellum|Migraine Disorders 22 TXNDC12 23978379 Carcinogenesis 2013 10.1093/carcin/bgt294 14 0 3 67 Humans|*Transcriptome|*Lung Adenocarcinoma|Adenocarcinoma|Lung Neoplasms|Prognosis|Biomarkers, Tumor|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Sequencing, RNA|Lung|Proportional Hazards Models|Tumor Microenvironment|CNTNAP1 protein, human|Cell Adhesion Molecules, Neuronal 19 wdfy1 23845568 Am. J. Pathol. 2013 PMC3763767 10.1016/j.ajpath.2013.05.020 21 1 6 79 Humans|Mice|Animals|*Ceruletide|*Mice, Inbred C57BL|*Risk Factors|*Chronic Pancreatitis|Pancreas|Pancreatic Stellate Cells|Mice, Transgenic|Fibrosis|Trypsinogen|Gene Expression|Cells, Cultured|Disease Models, Animal|Atrophy|Phenotypes|Actins|Itih4 protein, mouse|Calcium-Binding Proteins|Glycoproteins 19 wdfy1 23388383 Autophagy 2013 PMC3669190 10.4161/auto.23783 6 9 1 79 Vascular Endothelial Growth Factor C|Neuropilin-2|*Autophagy|Cell Line, Tumor|Cell Survival|*Intercellular Signaling Peptides and Proteins 19 5HT1 23035605 Lik. Sprava 2012 0 0 0 0 Humans|Adolescent|*Serotonin|Sumatriptan|Receptor Agonists, Serotonin|Migraine|Digestive System 176 APMAP 22267596 Gut 2012 10.1136/gutjnl-2011-301587 6 0 0 44 Humans|*Colorectal Cancer|*Liver Neoplasms|*Chromosomal Aberrations|*Colonic Neoplasms|Adenocarcinoma|Genetic Predisposition to Disease|Chromosomes|Liver 19 DNAI2 23261302 Am. J. Hum. Genet. 2012 PMC3542458 10.1016/j.ajhg.2012.11.003 49 0 0 30 Humans|*Exome|Kartagener Syndrome|*Whole Exome Sequencing|*Mutations|Axoneme|Axonemal Dyneins|Pedigree|Cilia|Phenotype 30 DNAI2 23118923 PLoS ONE 2012 PMC3485262 10.1371/journal.pone.0048037 0 14 0 30 Humans|*Acetylcysteine|Hydrogen Peroxide|*Respiratory Syncytial Viruses|*Bronchi|Respiratory Syncytial Virus Infection|*Cell Differentiation|Epithelial Cells|Mucin 5AC|Respiratory Epithelium|Goblet Cells|Cilia|Chronic Obstructive Pulmonary Disease|Virus Replication|Mucus 30 DNAI2 22385203 Br. J. Pharmacol. 2012 PMC3448891 10.1111/j.1476-5381.2012.01929.x 28 2 7 30 Humans|*PDE4 Inhibitors|roflumilast N-oxide|*Cilia|*Aminopyridines|*Benzamides|*Smoke|*Cyclopropanes|*Epithelial Cells|*Tobacco|Bronchi|Respiratory Mucosa|Chronic Obstructive Pulmonary Disease|Smoking|*Bronchioles|Cells, Cultured|Cyclic AMP|Cell Differentiation 30 FAM111A 23093934 PLoS Pathog. 2012 PMC3475652 10.1371/journal.ppat.1002949 17 28 0 19 *Adenovirus|*Host Specificity|Virus Replication|Large T-Antigen|Simian virus 40|Antigens, Polyomavirus Transforming|*Adenoviridae Infections|Tumor Suppressor Protein p53|Protein Binding|Cell Line 19 FAM111A 22366784 Nat. Genet. 2012 10.1038/ng.1104 50 0 9 19 Humans|Male|Genome-Wide Association Study|Japan|SNPs|Genetic Predisposition to Disease|*Prostate Cancer|Genotype|Genetic Loci|Gene Frequency|Case-Control Studies|Genome|Risk Factors|*Chromosome Structures 19 GSDMC 22567150 PLoS ONE 2012 PMC3342244 10.1371/journal.pone.0036346 16 2 0 11 Cattle|Animals|Male|Humans|*Quantitative Trait Loci|*Genome-Wide Association Study|Ultraviolet Rays|Chromosome Mapping|Breeding|Phenotypes|Single Nucleotide Polymorphisms|Genotype|Chromosomes|*Pigmentation|ATRN protein, human|Membrane Proteins|NBEAL2 protein, human|Blood Proteins 19 IFNK 23141412 Neurobiol. Aging 2012 10.1016/j.neurobiolaging.2012.09.018 5 0 1 71 Humans|Amyotrophic lateral sclerosis 1|Amyotrophic Lateral Sclerosis 9|*Amyotrophic Lateral Sclerosis|Genome-Wide Association Study|Neurodegenerative Diseases|C9orf72 Protein|Frontotemporal Dementia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Markers|*Open Reading Frames|Genetic Variation|DNA Mutational Analysis|*Chromosome Structures|C9orf72 protein, human 19 LMOD2 22901283 Pediatr Rheumatol Online J 2012 PMC3551672 10.1186/1546-0096-10-24 4 0 0 42 19 PASD1 22560555 Int. J. Radiat. Oncol. Biol. Phys. 2012 PMC3415596 10.1016/j.ijrobp.2012.03.017 124 1 10 15 Humans|Neoplasm Recurrence, Local|*Melanoma|Ipilimumab|Immunotherapy|Skin Neoplasms|Stereotactic Radiosurgery|Antibodies, Monoclonal|Brain Neoplasms|Combined Modality Therapy|PASD1 protein, human|Antigens, Neoplasm|Antigens, Nuclear 19 PCDH12 22765916 Brain Res. 2012 10.1016/j.brainres.2012.06.020 79 5 6 30 Humans|Genome-Wide Association Study|osteoblast cadherin|*Cadherins|H-cadherin|CDH10 protein, human|cadherin 5|Cell Adhesion|Neurogenesis|Cell Differentiation|Signal Transduction|Brain|Epilepsy|Autism|Antigens, CD|PCDH19 protein, human|PCDH10 protein, human|PCDH12 protein, human 27 pdlim3 22276141 PLoS ONE 2012 PMC3261849 10.1371/journal.pone.0030020 9 5 1 60 Humans|*Prognosis|*Tumor Suppressor Protein p53|*Transcriptome|Instability, Microsatellite|*Colorectal Neoplasms|*Adenocarcinoma|Proto-Oncogene Proteins B-raf|Microsatellite Repeats|DNA Methylation|Mutation|Adaptor Proteins, Signal Transducing|Phenotypes|TRIM29 protein, human|DNA-Binding Proteins|Transcription Factors|PDLIM3 protein, human|Microfilament Proteins|LIM Domain Proteins 35 PLCL2 22328738 Ann. Rheum. Dis. 2012 PMC3396450 10.1136/annrheumdis-2011-200802 13 1 1 21 *Arthritis, Psoriatic|*Rheumatoid Arthritis|*Cohort Studies|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Psoriasis|Case-Control Studies|Gene Frequency|Genotype 19 rtn2 23044792 Proteomics 2012 10.1002/pmic.201100559 9 0 1 109 Humans|Myofibrillar Myopathy|*Proteomics|*Protein Aggregates|Tandem Mass Spectrometry|*Myopathies, Structural, Congenital|Desmin|Myofibrils|FLNC protein, human|Filamin C|Muscle Proteins|Muscle, Skeletal|*Laser Capture Microdissection|PLEC protein, human|Plectin|TYRP1 protein, human|*Membrane Glycoproteins|Mutation|alpha-Crystallin B Chain 23 rtn2 22232211 J. Clin. Invest. 2012 PMC3266795 10.1172/JCI60560 54 1 2 109 *Spastic Paraplegia, Hereditary|Spastin|*Mutations|*Axons|Adenosine Triphosphatases|Membrane Proteins|Membrane Transport Proteins|GTP-Binding Proteins|Endoplasmic Reticulum|Northern Europe|North America 23 SERPINA9 22780928 Zhonghua Zhong Liu Za Zhi 2012 10.3760/cma.j.issn.0253-3766.2012.02.007 1 0 0 6 *Lymphoma, Large B-Cell, Diffuse|Proto-Oncogene Proteins c-bcl-6|*Prognosis|Vincristine|Germinal Center|Interferon Regulatory Factors|Cyclophosphamide|Antineoplastic Combined Chemotherapy Protocols|Central Nervous System Neoplasms|Proto-Oncogene Proteins c-bcl-2|Neprilysin|Survival Rate|Immunophenotyping|Prednisone|Doxorubicin|Nervous System 19 slamf8 23124178 J. Nerv. Ment. Dis. 2012 10.1097/NMD.0b013e3182718c6b 0 0 0 45 Humans|*Psychotherapy, Psychodynamic|*Follow-Up Studies|Anxiety Disorder|Psychotherapy, Brief|*Self Concept|Questionnaire|Social Behavior 19 slamf8 22593622 J. Immunol. 2012 PMC3370125 10.4049/jimmunol.1102620 17 16 3 45 Mice|Animals|Staphylococcus aureus|Escherichia coli|*Macrophages|NADPH Oxidases|Phagosomes|Receptors, Cell Surface|NADPH Oxidase 2|Membrane Glycoproteins|Antigens, CD|*Oxidation-Reduction|Reactive Oxygen Species|Mice, Knockout|Signal Transduction|Carrier Proteins|Inflammation 19 SMPX 22911656 Hum. Mutat. 2012 10.1002/humu.22205 5 0 0 17 *Founder Effect|Canada|*Hearing Loss|*Genes, X-Linked|Deafness|Stop Codon, Premature|Frameshift Mutation|Hearing Loss, Sensorineural|Pedigree|Genetic Diseases, X-Linked|Haplotype|Alleles|Mutation|Muscle Protein|Base Sequence|Sequence Analysis|Newfoundland 41 SNX14 22561202 Eur J Med Genet 2012 10.1016/j.ejmg.2012.03.003 9 0 1 37 Humans|*Intellectual Disability|Chromosome 6, monosomy 6q|Chromosome Deletion|*Chromosome 1|*Syndrome|Abnormalities, Multiple|Karyotyping|Phenotype|Genetic Association Studies|In Situ Hybridization, Fluorescence|Chromosomes, Human, Pair 6 22 taok2 22883308 Genes Brain Behav. 2012 PMC4011144 10.1111/j.1601-183X.2012.00834.x 11 17 1 143 Humans|Mice|Animals|*Ethanol|Central Nervous System Depressants|Alcoholism|Alcohol Drinking|Behavior, Animal|Locomotion|Motor Activity|Serine Threonine Kinases 19 taok2 22683681 Nat. Neurosci. 2012 PMC4017029 10.1038/nn.3141 56 45 4 143 Animals|Mice|*Neocortex|*Autism Spectrum Disorder|*Dendrites|Pyramidal Neurons|Semaphorin-3A|Neurons|Neuropilin-1|Axons|Signal Transduction|Phosphorylation|Neurogenesis|Cells, Cultured|Downregulation 19 TGM6 23206699 Biochem. Biophys. Res. Commun. 2012 10.1016/j.bbrc.2012.11.069 3 1 0 55 *Spinocerebellar Ataxias|Transglutaminases|Mutations, Missense|*Apoptosis|Pedigree|Mutation|Genetic Linkage|Peptides 22 TGM6 22554020 Clin. Genet. 2012 10.1111/j.1399-0004.2012.01895.x 15 0 0 55 Humans|*Whole Exome Sequencing|*Ataxia, Spinocerebellar|*Chinese|Pedigree|Exome|Mutations|Phenotype|Mutation, Missense|Transglutaminases 22 TGM6 22527681 Curr Neurol Neurosci Rep 2012 10.1007/s11910-012-0267-6 25 0 4 55 Humans|*Cerebellar Ataxia|Spinocerebellar Degenerations|Exome|Mutation|Cerebellum|Ataxia|Databases, Genetic 22 TGM6 22287014 Mov. Disord. 2012 PMC3323119 10.1002/mds.24064 11 1 0 55 *Cerebellar Ataxia|*Mutations|*Ataxia|Nerve Tissue Proteins|Nuclear Proteins|Cytoskeletal Proteins|Phenotype|Calcium Channels 22 TSPEAR 23091967 J Environ Health 2012 1 0 0 2 vermiculite|*Asbestos|Amphibole Asbestos|*Aluminum Silicates|Chrysotile|Occupational Exposure|Environmental Exposure|Montana 19 TSPEAR 22678063 Hum. Mol. Genet. 2012 10.1093/hmg/dds212 25 1 3 2 Humans|Animals|Mice|1-ethyl-4-phenyl-1,2,3,6-tetrahydropyridine|Iran|Deafness, Childhood-Onset Neurosensory, Autosomal Recessive 8|Hearing Loss, Sensorineural|gephyrin|Membrane Proteins|Genes, Recessive|Mutation|Carrier Proteins|Mutation, Frame Shift|Pedigree|*Protein Domain|Base Sequence|Amino Acid Sequence|LGI1 protein, human|Deafness|Chromosome Mapping|Alternative Splicing 19 TXNDC12 22789714 Fish Shellfish Immunol. 2012 10.1016/j.fsi.2012.06.030 1 0 0 67 Animals|Mice|*Bass|Fish Proteins|Ranavirus|Cloning, Molecular|DNA, Complementary|TXN protein, human|Thioredoxin|Sequence Alignment|Amino Acid Sequence|mRNA|Base Sequence|PCR|Gene Expression Regulation|Phylogeny 19 5HT1 21481285 BMJ Clin Evid 2011 PMC3275150 3 0 0 0 Child|Humans|Adult|Sexual Maturation|*Headache, Migraine|Acetaminophen|Anti-Inflammatory Agents, Non-Steroidal 176 APMAP 21845885 Zhongguo Ying Yong Sheng Li Xue Za Zhi 2011 0 0 0 44 Rats|Animals|*Antibodies|*Adipocyte|Adipose Tissue|Leptin|Body Composition|Body Weight|Triglycerides|Fatty Acids, Nonesterified|Insulin|Blood Glucose|*Membrane Proteins 19 DDRGK1 21659334 Hum. Mol. Genet. 2011 10.1093/hmg/ddr249 0 0 4 145 Humans|*Ribavirin|*Hepatitis C, Chronic|*Genome-Wide Association Study|Antiviral Agents|Interferon-alpha|*Anemia|Hepacivirus|Interferon alpha-2|Pyrophosphatases|Genotype|Polyethylene Glycols|*Thrombocytopenia|*Leukopenia|Drug Therapy, Combination|Single Nucleotide Polymorphism|Hemoglobin|Linkage Disequilibrium|Platelet Count 19 DRC1 21593208 Mol. Biol. Cell 2011 PMC3135486 10.1091/mbc.E10-12-0995 19 57 2 38 *Schizosaccharomyces|*Cyclin-Dependent Kinases|Replication Origins|Schizosaccharomyces pombe Proteins|Cell Cycle Proteins|DNA Replication|S Phase|Chromosomes, Fungal|DNA-Binding Proteins|Saccharomyces cerevisiae Proteins|Phosphorylation|Budding Yeast|DNA, Fungal|Nuclear Proteins|Protein Binding|*Biochemical Phenomena 45 IFNK 21944779 Neuron 2011 PMC3200438 10.1016/j.neuron.2011.09.010 1234 1 73 71 Frontotemporal Dementia With Motor Neuron Disease|*Frontotemporal Dementia|Amyotrophic Lateral Sclerosis 2, Juvenile|*Amyotrophic Lateral Sclerosis|*C9orf72 Protein|DNA Repeat Expansion|Haplotype|Genotype|Proteins|Polymorphism, Single Nucleotide|Mutation|Intron|Chromosomes|Finland 19 IMPG2 22057785 Acta Neuropathol. 2011 PMC3306784 10.1007/s00401-011-0899-7 122 0 6 17 United States|*Medulloblastoma|Reproducibility of Results|Cerebellar Neoplasms|Gene Expression Profiling|Hedgehog Proteins|Wnt Proteins|Prognosis|Canada|Switzerland 26 LMOD2 22157009 J. Biol. Chem. 2011 PMC3268406 10.1074/jbc.M111.302224 37 0 5 42 Humans|Mice|Rats|Animals|*Serum Response Factor|myocardin|Trans-Activators|Nuclear Proteins|*Cell Differentiation|Smooth Muscle Cell|Gene Expression Regulation|Promoter Regions, Genetic|Transcription, Genetic|Muscle Proteins|Transgenic Mouse|Cells, Cultured|Electrophoretic Mobility Shift Assay|leiomodin 2 protein, human|Microfilament Proteins|leiomodin 2 protein, rat 19 PCDH12 22205043 Pathol. Biol. 2011 10.1016/j.patbio.2011.11.005 6 0 0 30 Female|Pregnancy|Mice|Animals|Endothelial Cells|Carotid Artery|Blood Pressure|Muscle, Smooth, Vascular|Carotid Artery, Common|Elastin|Cell Adhesion|Cadherins|Placenta|Pcdh12 protein, mouse 27 PCDH12 21573496 Oncol. Rep. 2011 10.3892/or.2011.1286 6 1 1 30 *Carcinoma, Adenoid Cystic|Neoplasm Recurrence, Local|Salivary Gland Neoplasms|Neoplasm Invasiveness|Cadherins|RNA, Small Interfering|Cell Line, Tumor|Cell Movement|Genetic Vectors 27 PCDH12 21402705 J. Biol. Chem. 2011 PMC3083177 10.1074/jbc.M111.230045 5 0 1 30 Female|Humans|Mice|Pregnancy|Animals|*ADAM10 Protein|*Pre-Eclampsia|Endothelial Cells|*Up-Regulation|Secretase|ADAM Proteins|Cadherins|Membrane Proteins|Trophoblast|Cell Adhesion|Placenta|Protein Kinase C|RNA, Small Interfering|ADAM10 protein, human|PCDH12 protein, human|Adam10 protein, mouse|Pcdh12 protein, mouse 27 pdlim3 21907276 Genomics 2011 PMC3229301 10.1016/j.ygeno.2011.08.003 6 16 1 60 Animals|Humans|*Myogenesis|*Cell Differentiation|Myogenin|Myogenic Regulatory Factors|Transcription Factors|Regulatory Regions|DNA-Binding Proteins|Promoter Regions, Genetic|Gene Expression Regulation|Binding Sites|Protein Binding|Myoblasts|Cells, Cultured|Muscle, Skeletal|PDLIM3 protein, human|Microfilament Proteins|LIM Domain Proteins 35 pdlim3 21620799 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.05.054 0 2 0 60 *Muscle Development|*Cell Differentiation|Myogenin|Cell Nucleus|Cytoplasm|Myoblasts|Actin|*Cytoskeletal Proteins|Cytoskeleton|Skeletal Muscles|*Protein Transport|Transfection|Protein Isoforms|Cell Line|Muscle Fibers, Skeletal 35 pdlim3 21549096 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.04.106 12 3 0 60 Humans|Adult|*Myotonic Dystrophy|*Alternative Splicing|*Actinin|Protein Kinase, DM|RNA Splicing|RNA-Binding Proteins|Skeletal Muscles|Exons|RNA|PDLIM3 protein, human|Microfilament Proteins|LIM Domain Proteins 35 POU5F1B 22142333 BMC Med. Genet. 2011 PMC3267702 10.1186/1471-2350-12-156 15 3 1 44 Humans|Male|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Case-Control Studies|Prostatic Neoplasms|Risk Factors|alkylglycerophosphoethanolamine phosphodiesterase|*Phosphoric Diester Hydrolases 19 POU5F1B 21372204 Cancer Res. 2011 PMC3085580 10.1158/0008-5472.CAN-10-2646 18 7 3 44 Humans|Male|*Genome-Wide Association Study|Follow-Up Studies|Bayes Theorem|*Epistasis, Genetic|*Prostate Cancer|SNPs|Prostate-Specific Antigen|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Logistic Regression|Genome|Risk Factors 19 rtn2 21542987 Chin. Med. J. 2011 1 0 0 109 *Retinal Pigment Epithelium|*Transcriptome|*Phagocytosis|c-Mer Tyrosine Kinase|Receptor Protein-Tyrosine Kinases|Retinal Photoreceptor Cell Outer Segment|Proto-Oncogene Proteins|Cells, Cultured|*Microarray Analysis 23 rtn2 21258182 J. Vet. Med. Sci. 2011 10.1292/jvms.10-0543 1 0 0 109 Mice|Animals|*Phosphorylation|Aminoimidazole Carboxamide|Ribonucleotides|Muscle, Skeletal|AMP-Activated Protein Kinases|Acetyl-CoA Carboxylase|Physical Conditioning, Animal|Blood Glucose|Glucose|Adenosine Monophosphate|Ribonucleosides|Adenosine Triphosphate 23 SERPINA9 21832150 J. Histochem. Cytochem. 2011 PMC3201129 10.1369/0022155411417309 3 0 0 6 Comparative Genomic Hybridization|*Lymphoma, Large B-Cell, Diffuse|Proto-Oncogene Proteins c-bcl-6|Germinal Center|Neprilysin|Prognosis|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Interferon Regulatory Factors|Repressor Proteins|Chromosomal Aberrations|Forkhead Transcription Factors 19 SERPINA9 21615994 Zhonghua Bing Li Xue Za Zhi 2011 0 0 0 6 *Prognosis|*Lymphoma, Large B-Cell, Diffuse|Proto-Oncogene Proteins c-bcl-6|Vincristine|Cyclophosphamide|Antineoplastic Combined Chemotherapy Protocols|Immunophenotyping|Germinal Center|Prednisone|Proto-Oncogene Proteins c-bcl-2|Neprilysin|Interferon Regulatory Factors|Doxorubicin|DNA-Binding Proteins|Survival Rate|Retrospective Studies 19 slamf8 21667045 Immunogenetics 2011 10.1007/s00251-011-0544-6 4 0 1 45 Animals|Phylogeny|SLAMF1 protein, human|Signaling Lymphocytic Activation Molecule Family Member 1|Amino Acid Sequence|Sequence Alignment|CD2 Antigens|Antigens, CD|Signaling Lymphocytic Activation Molecule Family|*Amphibians|Receptors, KIR|*Signal Transduction|Gene Expression|Sequence Homology, Amino Acid|Genome|CD58 Antigens|Mammals 19 SPATA5 22027810 Eur. J. Hum. Genet. 2011 PMC3283178 10.1038/ejhg.2011.185 12 0 2 119 Male|*Alopecia Areata|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Alleles|Genotype|Case-Control Studies 19 TGM6 21984379 Amino Acids 2011 PMC3535377 10.1007/s00726-011-1091-z 22 7 2 55 Humans|Animals|Mice|Transglutaminases|Central Nervous System|Neurons|Post-Translational Modifications|Ataxia|Peptides|Cell Line|mRNA|Alternative Splicing|Glutamine|*Organogenesis 22 TGM6 21683323 Am. J. Hum. Genet. 2011 PMC3135815 10.1016/j.ajhg.2011.05.015 70 2 4 55 Humans|In Situ Hybridization, Fluorescence|*Ataxia, Spinocerebellar|*Introns|*Motor Neuron|Trinucleotide Repeat Expansion|Genetic Linkage|Pedigree|Lod Score|Haplotype|Phenotype|Amyotrophic Lateral Sclerosis|Base Sequence|Brain|Nuclear Proteins|Mutation, Missense|Mutations 22 TXNDC12 21477593 J. Mol. Biol. 2011 10.1016/j.jmb.2011.03.070 14 0 4 67 Humans|KDEL receptor|Receptors, Peptide|Endoplasmic Reticulum|Protein Sorting Signals|Carrier Proteins|Amino Acid Sequence|Amino Acid Motifs|Membrane Proteins|Protein Disulfide-Isomerases|HeLa Cells|Biological Transport 19 TXNDC12 21346809 PLoS ONE 2011 PMC3035619 10.1371/journal.pone.0016766 21 1 4 67 Swine|Animals|*Genetic Linkage|Quantitative Trait Loci|Chromosome Mapping|Sus scrofa|Phenotype|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|*Gene Expression|Gene Expression Regulation|Meat|mRNA|Muscle, Skeletal|Polymorphism, Single Nucleotide 19 wdfy1 21321390 J. Alzheimers Dis. 2011 10.3233/JAD-2011-101881 32 0 4 79 Humans|Animals|Mice|*Alzheimer Disease|*Brain|*Disease Models, Animal|Transgenic Mouse|*Gene Expression|Oligonucleotide Array Sequence Analysis|*Biomarkers|Gene Expression Profiling|*Diagnostic Tests, Routine|mRNA|*Logic|ACTL6A protein, human|Actins|Chromosomal Proteins, Non-Histone|DNA-Binding Proteins 19 5HT1 21181116 Naunyn Schmiedebergs Arch. Pharmacol. 2010 10.1007/s00210-010-0587-5 1 2 0 0 Animals|Rats|*cAMP Response Element Binding Protein|*N-Methyl-3,4-methylenedioxyamphetamine|*Serotonin|*MAP Kinase Signaling System|preproenkephalin|Enkephalins|pronociceptin|Receptors, Opioid|nociceptin|Opioid Peptides|*Gene Expression|Protein Precursors|Dynorphin|kappa Opioid Receptor|Gene Expression Regulation|Phosphorylation|mRNA|*Brainstem 176 5HT1 20420788 Int J Clin Pharmacol Ther 2010 10.5414/cpp48319 0 0 0 0 Humans|*Serotonin 5-HT1 Receptor Agonists|Triptans|*Migraine|Serotonin Receptor Agonists|*Databases, Pharmaceutical|Triazoles 176 APMAP 20552250 Cell. Mol. Life Sci. 2010 10.1007/s00018-010-0424-5 15 3 0 44 Humans|Mice|Animals|*Adipogenesis|3T3-L1 Cells|Adipocytes|*Network, Gene|Cell Differentiation|PPAR gamma|Rosiglitazone|Adipose Tissue|*Membrane Proteins|Obesity|Diet, High-Fat|Signal Transduction|RNA, Messenger|RNA, Small Interfering 19 CDKN2AIP 21052095 Cell Death Differ. 2010 PMC3131902 10.1038/cdd.2010.129 12 4 2 154 Humans|Mice|Animals|*Apoptosis|*Cancer|DNA Damage|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|Tumor Suppressor Protein p53|DNA-Binding Proteins|Phosphorylation|Signal Transduction|shRNA|Mitogen-Activated Protein Kinases 19 CEP120 20956381 J. Cell Biol. 2010 PMC2958470 10.1083/jcb.201003009 46 6 6 226 Mice|Animals|*Centrioles|Centrosome|Cilia|Cell Cycle Proteins|Cell Cycle|Cell Line|Cells, Cultured|Cells, Epithelial|Basal Bodies|Cell Differentiation|Nuclear Family 22 CEP120 20824097 PLoS Pathog. 2010 PMC2932726 10.1371/journal.ppat.1001088 38 1 4 226 Humans|Mice|Animals|*Quantitative Trait Loci|*Staphylococcus aureus|*Chromosomes, Human, Pair 18|*C57BL Mice|*Mice, Inbred Strains|Chromosome Mapping|*Staphylococcus aureus Infection|Genetic Susceptibility|Chromosomes, Mammalian|Polymorphism, Single Nucleotide|Gene Expression Profiling|Phenotype|Sepsis|Bacteremia|LMAN1 protein, human|Membrane Proteins|Mannose-Binding Lectins|CHMP1B protein, human 22 CEP120 20685982 J. Neurosci. 2010 PMC6634663 10.1523/JNEUROSCI.0381-10.2010 56 0 5 226 Humans|Infant, Newborn|*Neocortex|*Centrosome|*Axons|*Cell Movement|Neurons|Microtubules|Golgi Apparatus|Microtubule-Associated Proteins|Cell Polarity|Neurogenesis|Cell Differentiation|Cytoskeletal Proteins 22 DDRGK1 20228063 J. Biol. Chem. 2010 PMC2865345 10.1074/jbc.M110.110619 38 1 3 145 Humans|*NF-kappa B|*Protein A|RELA protein, human|*Transcription Factor RelA|*Signal Transduction|Intracellular Signaling Peptides and Proteins|Nerve Tissue Proteins|HeLa Cells|Protein Binding|Apoptosis|Cell Line, Tumor|CDK5RAP3 protein, human 19 DISP1 20951845 Eur J Med Genet 2010 10.1016/j.ejmg.2010.10.002 10 2 0 24 Humans|Hedgehog Proteins|*Chromosome Disorders|Chromosome Deletion|Abnormalities, Multiple|Comparative Genomic Hybridization|Intellectual Disability|Phenotype|Syndrome|Fryns syndrome|Facies|Haploinsufficiency|Limb Deformities, Congenital|Genotype-Phenotype Correlations|In Situ Hybridization, Fluorescence|Hernia, Diaphragmatic|Seizures|Cleft Palate|Cohort Studies 34 DISP1 20799323 Am. J. Med. Genet. 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Genet. 2010 10.1007/s00439-009-0778-7 20 0 0 24 Humans|*Holoprosencephaly|Comparative Genomic Hybridization|Homeodomain Proteins|*Phenotypes|Eye Proteins|Transcription Factors|Repressor Proteins|Nerve Tissue Proteins|Nuclear Proteins|Prosencephalon|Hedgehog Proteins|Mutations|Genes, Homeobox|TGIF1 protein, human 34 FAM111A 20927350 PLoS ONE 2010 PMC2948035 10.1371/journal.pone.0013100 157 4 18 19 Male|Humans|Rats|Animals|vinclozolin|*Epigenome|DNA Copy Number Variations|*Sperm|Epigenesis, Genetic|*Oxazoles|DNA Methylation|Germ Line|Infertility, Male|*Epigenetic|Heredity|Endocrine Disruptors|Promoter Regions, Genetic|Rats, Sprague-Dawley|Genome 19 FSCN2 20660251 J. Neurosci. 2010 PMC2922854 10.1523/JNEUROSCI.1541-10.2010 63 1 4 24 Animals|Mice|*Mice, Inbred DBA|fascin|*Stereocilia|*Actins|Mechanotransduction, Cellular|Chickens|*Microfilament Proteins|*Carrier Proteins|FSCN1 protein, human|*Deafness|Evoked Potentials, Auditory, Brain Stem|Presbycusis|Mice, Inbred C57BL|Phenotype|Quantitative Trait Locus|Cadherins 34 IFNK 20706608 J. Biomed. Biotechnol. 2010 PMC2914299 10.1155/2010/706825 22 2 0 71 Humans|Male|Female|interferon kappa|*Type I Interferons|*Lupus Erythematosus, Systemic|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Haplotypes|Asian|Linkage Disequilibrium|European Continental Ancestry Group|African Americans|Hispanic Americans|Case-Control Studies|Phenotypes 19 IFNK 20663124 BMC Genomics 2010 PMC3091641 10.1186/1471-2164-11-444 24 0 0 71 Humans|Animals|*Interferon|Bats|*Antiviral Agents|*Base Sequence|*Chromosome Mapping|Genome|Phylogeny|Evolution, Molecular|Amino Acid Sequence|Immunity, Innate 19 IMPG2 20673862 Am. J. Hum. Genet. 2010 PMC2917719 10.1016/j.ajhg.2010.07.004 30 1 2 17 Humans|*Retinitis Pigmentosa|Homozygote|Genes, Recessive|*Mutations|DNA Mutational Analysis|Exon|Eye Proteins|Pedigree|Mutation, Nonsense|Base Sequence|Amino Acid Sequence|Fundus Oculi|Missense Mutation|Visual Field Tests|Sequence Analysis|Proteoglycan 26 LMOD2 20736303 J. Cell. Sci. 2010 PMC2931607 10.1242/jcs.071837 51 1 4 42 *Tropomodulin|*Actin Filament|*Sarcomeres|*Cardiac Muscle|Actin|Tropomyosin|Muscle Proteins|Cardiomyocytes|Muscle, Striated|Muscle, Skeletal|Carrier Proteins|Protein Binding|Binding Sites|*Musculoskeletal Physiological Phenomena|Amino Acid Sequence|Protein Isoforms 19 MYNN 21154063 Avian Pathol. 2010 10.1080/03079457.2010.530938 2 0 1 15 Animals|Phylogeny|*Newcastle disease virus|Newcastle Disease|*Galliformes|*Molecular Epidemiologies|Pigeons|Viral Fusion Proteins|Chickens|Base Sequence|Poultry|Genotype 19 MYNN 20386695 PLoS ONE 2010 PMC2851616 10.1371/journal.pone.0009983 48 1 6 15 Humans|Female|*Carcinoma, Ovarian Epithelial|*DNA Copy Number Variations|*Ovarian Cancer|Gene Dosage|Oligonucleotide Array Sequence Analysis|Gene Amplification|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Polymorphism, Single Nucleotide|TPX2 protein, human|Microtubule-Associated Proteins|Nuclear Proteins|Cell Cycle Proteins|MYNN protein, human|Kruppel-Like Transcription Factors 19 PASD1 20861911 Leukemia 2010 10.1038/leu.2010.196 4 0 0 15 Male|Humans|Mice|Animals|*Vaccines, DNA|*Multiple Myeloma|*B-DNA|*Testis|HLA-A2 Antigen|PASD1 protein, human|Antigens, Neoplasm|Cytotoxic T-Lymphocytes|Cancer Vaccines|Epitopes|Antigen Presentation|Antigens, Nuclear|Mice, Transgenic|Peptides|Histocompatibility Antigens Class I|Vaccination 19 PASD1 20851862 Haematologica 2010 PMC3012768 10.3324/haematol.2010.028241 2 0 0 15 Humans|Male|*Helper Cell|*Lymphoma, Large B-Cell, Diffuse|Tumor Antigens|CD4-Positive T-Lymphocytes|T-Lymphocytes, Cytotoxic|CD8-Positive T-Lymphocytes|Cancer Vaccines|Epitopes|Dendritic Cells|Amino Acid Sequence|PASD1 protein, human|Antigens, Nuclear 19 PASD1 20726502 Cancer Immun. 2010 PMC2964014 21 0 0 15 Humans|Male|*Testis|*Testicular Neoplasms|*Oncogenes|*Malignancies, Hematological|Antigens, Neoplasm|T-Lymphocytes, Cytotoxic|Neoplasm Proteins|SPA17 protein, human|Antigens, Surface|Carrier Proteins|Lymphoma, Large B-Cell, Diffuse|KDM5B protein, human|Nuclear Proteins|Western Blotting|Gene Expression Regulation, Neoplastic|Immunohistochemistry|Repressor Proteins|Jumonji Domain-Containing Histone Demethylases 19 PASD1 20589424 Virus Genes 2010 10.1007/s11262-010-0503-6 1 0 1 15 Cattle|Animals|*Bovine Viral Diarrhea Virus Type 2|Bovine Viral Diarrhea Viruses|Cytopathogenic Effect, Viral|*Virus Replication|Diarrhea Virus 1, Bovine Viral|Viral Nonstructural Proteins|cDNA|Amino Acid Sequence|RNA, Viral|Cell Line|*DNA Viruses|Cells, Cultured|*Peptides|*Amino Acids|Diabetes Mellitus, Type 2 19 PCDH12 21173574 Cell Adh Migr 2010 PMC3084973 10.4161/cam.5.2.14374 73 0 9 30 Phylogeny|Cadherins|Neurons|Isoforms|Cell Adhesion|Gene Expression Regulation, Developmental|Hippocampal Formation|Cell Signaling|Brain 27 pdlim3 21139803 Am J Transl Res 2010 PMC2981423 26 0 0 60 Humans|Mice|Rats|Animals|*Urinary Bladder Neoplasms|*Rodents|*Gene Expression|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|*Carcinogens|Gene Expression Regulation, Neoplastic|Downregulation|Up-Regulation|Cluster Analysis|Genes, cdc|Rats, Inbred F344|Cell Cycle|Proteins|ITIH5 protein, human|Proteinase Inhibitory Proteins, Secretory|KIF20A protein, human|Kinesin 35 PLCL2 20340178 Synapse 2010 10.1002/syn.20798 0 1 0 21 Mice|Animals|*Dopamine Agonists|*Mice, Knockout|*Diazepam|SK&F 83959|*2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine|Receptors, Dopamine D1|*Movements|Receptors, Dopamine D2|Jaw|Vibrissae|Face|*GABAergic Agent|Mice, Inbred C57BL|Head|Phenotype|Type C Phospholipases|PRIP-1 protein, mouse|Adaptor Proteins, Signal Transducing 19 PLCL2 20097266 Neurosci. Lett. 2010 10.1016/j.neulet.2010.01.031 3 1 0 21 Mice|Animals|*Isoflurane|*Receptors, GABA-A|Anesthetics, Inhalation|gamma-Aminobutyric Acid|Patch-Clamp Techniques|Protein Subunits|Membrane Potentials|Neurons 19 rtn2 20805477 Proc. Natl. Acad. Sci. U.S.A. 2010 PMC2941330 10.1073/pnas.1011105107 68 0 4 109 *RNA, Viral|Brome mosaic virus|Endoplasmic Reticulum|Saccharomyces cerevisiae|TYRP1 protein, human|*Membrane Glycoproteins|Viral Proteins|Virus Replication|Cell Membrane|Membrane Proteins|*Membrane 23 s100a5 20621410 Biophys. Chem. 2010 PMC2926197 10.1016/j.bpc.2010.06.003 17 3 1 15 *S100 Proteins|Protein Structure, Quaternary|Protein Multimerization|Dimerization|*Ions 39 SERPINA9 20654154 Zhonghua Bing Li Xue Za Zhi 2010 4 0 0 6 Humans|*Prevalence|China|*Germinal Center|*Lymphoma, Large B-Cell, Diffuse|*B-Lymphocytes|Proto-Oncogene Proteins c-bcl-6|Interferon Regulatory Factors|DNA-Binding Proteins|Translocation, Genetic|Neprilysin 19 slamf8 20933010 Immunol. Lett. 2010 10.1016/j.imlet.2010.09.019 24 0 2 45 Humans|*B Cells|*Leukocyte Differentiation Antigens, Human|Plasma Cells|FCRL2 protein, human|Receptors, Cell Surface|Subsets, B-Cell|Lymphocyte Activation|class-I restricted T cell-associated molecule|FCRL1 protein, human|Membrane Proteins|Flow Cytometry|Antibodies, Monoclonal|Bone Marrow Cells|Cell Differentiation|Leukocytes|Monocytes|FCRL4 protein, human|Receptors, Fc 19 TGM6 21106500 Brain 2010 10.1093/brain/awq323 88 0 5 55 Humans|*Whole Exome Sequencing|*Exome|*Spinocerebellar Ataxias|Genetic Linkage|Pedigree|Spinocerebellar Degenerations|Mutation|Phenotype|Missense Mutation|Exon|Chinese|Gene Mapping|Base Sequence 22 TXNDC12 21117079 Proteins 2010 10.1002/prot.22893 2 0 0 67 Humans|*Protein Structure, Secondary|TXNDC12 protein, human|*Protein Disulfide Reductase (Glutathione)|Protein Conformation|Amino Acid Sequence|Nuclear Magnetic Resonance, Biomolecular|*Endoplasmic Reticulum|TXN protein, human|Thioredoxin|Models, Molecular|Sequence Alignment|Magnetic Resonance Spectroscopy|Amino Acids|Computer Simulation|Oxidation-Reduction 19 TXNDC12 20920593 Int. J. Biochem. Cell Biol. 2010 10.1016/j.biocel.2010.09.019 21 7 2 67 Protein Disulfide-Isomerases|Heat-Shock Proteins|Endoplasmic Reticulum|Molecular Chaperones|TXN protein, human|Thioredoxin|Cell Line, Tumor|Cell Transformation, Neoplastic|Epithelial-Mesenchymal Transition|Redox|Transfection 19 5HT1 19551474 Intern Emerg Med 2009 10.1007/s11739-009-0273-0 7 0 1 0 Humans|*Migraine|Calcitonin Gene-Related Peptide Receptor Antagonists|Calcitonin Gene-Related Peptide|Triptans|1-(N(2)-(3,4-dibromo-N-((4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl)carbonyl)tyrosyl)lysyl)-4-(4-pyridinyl)piperazine|Quinazolines|telcagepant|Azepines|Receptors, Calcitonin Gene-Related Peptide|olcegepant|Imidazoles|Dipeptides|Sumatriptan|Anti-Inflammatory Agents, Non-Steroidal|candesartan|Benzimidazoles|Tetrazoles|Trigeminal Nerves 176 CDKN2AIP 19587106 J. Gerontol. A Biol. Sci. Med. Sci. 2009 10.1093/gerona/glp088 9 0 0 154 Humans|6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide|Ashwagandha|Quality of Life|*Deceleration|*Withania|*Triterpenes|*Plant Extracts|withaferin A|Withanolides|*Fibroblasts|Cell Proliferation|Cell Line, Tumor 19 CDKN2AIP 19457610 Cancer Lett. 2009 PMC3182267 10.1016/j.canlet.2009.04.017 17 16 1 154 Humans|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Neoplastic|Nerve Tissue Proteins|Circadian Rhythm|Cell Line, Tumor|Cell Cycle|Cell Transformation, Neoplastic|ELF4 protein, human|DNA-Binding Proteins|Transcription Factors|NPAS2 protein, human 19 DISP1 20023168 Development 2009 PMC2796928 10.1242/dev.043547 27 0 2 24 Animals|Hedgehog Proteins|*Signal Transduction|Embryonic Stem Cells|Membrane Proteins|*Vertebrate|Cell Differentiation|Trans-Activators|Embryoid Bodies|RNAi 34 DRC1 19937211 Folia Microbiol. (Praha) 2009 10.1007/s12223-009-0055-0 0 0 0 38 *Lactococcus lactis|*Bile|*Plasmid|*Drug Tolerance|Fatty Acids|3'-(1-butylphosphoryl)adenosine|Genetic Vectors|Probiotic|*Complement Factor B 45 IFNE 19393062 BMC Genomics 2009 PMC2680415 10.1186/1471-2164-10-187 23 2 0 58 Cattle|Animals|Evolution, Molecular|Chromosome Mapping|Multigene Family|Phylogeny|Pseudogenes|Amino Acid Sequence|Type I Interferons|Mammals|Sequence Homology, Amino Acid 19 IFNK 19393062 BMC Genomics 2009 PMC2680415 10.1186/1471-2164-10-187 23 2 0 71 Cattle|Animals|Evolution, Molecular|Chromosome Mapping|Multigene Family|Phylogeny|Pseudogenes|Amino Acid Sequence|Type I Interferons|Mammals|Sequence Homology, Amino Acid 19 IGSF9 19906964 J. Neurosci. 2009 PMC6665052 10.1523/JNEUROSCI.2497-09.2009 16 0 1 96 Animals|*Drosophila|*Turtles|*Axons|Drosophila Proteins|Nerve Tissue Proteins|Neurons|Membrane Proteins|Activin|Neurites|Gene Expression Regulation, Developmental|Signal Transduction|Cell Communication|tutl protein, Drosophila|Immunoglobulins 19 LMOD2 19254430 Int. J. Neuropsychopharmacol. 2009 10.1017/S1461145709009997 7 2 1 42 Rats|Animals|*Phencyclidine|Haloperidol|Dopamine Antagonists|Dizocilpine|*Thalamus|Excitatory Amino Acid Antagonists|Dopamine Agonist|Receptors, N-Methyl-D-Aspartate|Ketamine|N Methyl D aspartate|Schizophrenia 19 PASD1 19886887 Br. J. Dermatol. 2009 10.1111/j.1365-2133.2009.09568.x 11 0 2 15 Male|Female|*Testis|*Basal Cell Carcinoma|Antigens, Neoplasm|Skin Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Neoplasms, Basal Cell|Immunotherapy 19 PASD1 19552722 Br. J. Haematol. 2009 10.1111/j.1365-2141.2009.07761.x 10 0 2 15 Humans|Male|*Testis|Leukocytes, Mononuclear|*T-Lymphocytes, Cytotoxic|*Lymphoma, Large B-Cell, Diffuse|Antigens, Neoplasm|Histocompatibility Antigens Class I|Interferon-gamma|PASD1 protein, human|Antigens, Nuclear 19 pdlim3 19888305 Eur. J. Hum. Genet. 2009 PMC2843500 10.1038/ejhg.2009.183 17 3 0 60 *Muscular Dystrophy, Facioscapulohumeral|*Alleles|*RNA|*DNA|Chromatin|Myoblasts|Myotubes|Telomere|Tandem Repeat Sequences|Nucleic Acid Hybridization|Gene Expression|Cell Differentiation 35 pdlim3 19725780 Thyroid 2009 10.1089/thy.2009.0008 28 0 4 60 Child|Humans|*Thyroid Cancer, Papillary|*Chernobyl Nuclear Accident|*DNA Copy Number Variations|Carcinoma, Papillary|Thyroid Neoplasms|Neoplasms, Radiation-Induced|*Gene Expression Regulation 35 PLCL2 19553601 Biol. Reprod. 2009 10.1095/biolreprod.109.076760 11 0 3 21 Female|Male|Mice|Animals|*Phospholipase C|*Phospholipase|*Protein C|Follicle Stimulating Hormone|Luteinizing Hormone|Reproduction|Mice, Knockout|Estradiol|Fertility|Reproductive System|PRIP-1 protein, mouse|Adaptor Proteins, Signal Transducing|PRIP-1 phospholipase C-related protein, mouse|Carrier Proteins 19 rtn2 19720795 Diabetes 2009 PMC2780876 10.2337/db09-0756 3 16 0 109 Animals|*Glucose Transporter Type 4|RTN1 protein, human|*Nerve Tissue Proteins|Skeletal Muscles|Dantrolene|Glucose|Muscle Proteins|Sarcoplasmic Reticulum|Insulin|Biological Transport|Physical Conditioning, Animal|Blood Glucose|RTN4 protein, human|*Nogo Proteins|Phosphorylation|*Membrane 23 s100a5 19740107 FEBS J. 2009 10.1111/j.1742-4658.2009.07274.x 21 9 4 15 Mice|Animals|*S100 Calcium-Binding Protein A4|*Ligands|AREG protein, human|Amphiregulin|Epidermal Growth Factor|EGFR protein, human|HBEGF protein, human|HB EGF|Receptor, ErbB-2|Glycoproteins|Signal Transduction|Cell Proliferation|Protein Binding|Phosphorylation 39 s100a5 19536568 J. Biol. Inorg. Chem. 2009 10.1007/s00775-009-0553-1 4 0 1 15 *Calcium|EF Hand Motifs|Protein Conformation|Calcium-Binding Proteins|Protein Structure, Secondary|Nerve Growth Factors|Dimerization|Apoproteins|Models, Molecular|Amino Acid Sequence|Nuclear Magnetic Resonance, Biomolecular|S100 Calcium Binding Protein beta Subunit|Hydrophobic and Hydrophilic Interactions|Magnetic Resonance Spectroscopy 39 TXNDC12 19887585 J. Cell. Sci. 2009 PMC2779130 10.1242/jcs.059154 74 1 2 67 Animals|PDIA3 protein, human|*Protein Disulfide-Isomerases|*Substrate Specificity|*Binding Proteins|Endoplasmic Reticulum|endoplasmic reticulum glycoprotein p72|Membrane Glycoproteins|Protein Folding|Oxidoreductases|Protein Binding|Disulfides|Oxidation-Reduction|PRDX4 protein, human|Thioredoxin Peroxidase|Catalysis 19 TXNDC12 19361226 Biochemistry 2009 10.1021/bi9003342 10 0 0 67 Thiol Disulfide Oxidoreductase|*Oxidase|TXN protein, human|Thioredoxin|*Endoplasmic Reticulum|Protein Disulfide-Isomerases|Oxidation-Reduction|Amino Acid Sequence|Disulfides|Binding Sites|Molecular Conformation|NMR Spectroscopy|Models, Molecular|Sulfhydryl Compounds|Sequence Homology, Amino Acid 19 TXNDC12 19274343 Braz. J. Med. Biol. Res. 2009 PMC2654581 10.1590/s0100-879x2009000200003 1 1 0 67 Humans|Chlorocebus aethiops|Animals|GNRHR protein, human|*Receptors, LHRH|*Endoplasmic Reticulum|*Plasma Membrane|COS-7 Cells|*Molecular Chaperones|Buserelin|Amino Acid Sequence|Protein Disulfide-Isomerases|Inositol Phosphates|Transfections|Disulfides|*Oxidoreductases 19 wdfy1 19296456 Proteins 2009 PMC2909462 10.1002/prot.22392 27 6 1 79 phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|PtdIns|Binding Sites|Amino Acid Sequence|Vesicular Transport Proteins|Membrane Proteins|Static Electricity|Models, Molecular|Hydrogen-Ion Concentration 19 wdfy1 19228596 Biol. Reprod. 2009 PMC3093993 10.1095/biolreprod.108.073312 20 1 1 79 Mice|Female|Pregnancy|Animals|*Trophoblasts|sargramostim|*Granulocyte-Macrophage Colony-Stimulating Factor|*Glycogen|*Loss of Function Mutation|*Placenta|*Giant Cell|Placental Development|*Gene Expression|Cell Differentiation|CDKN1C protein, human|Cyclin-Dependent Kinase Inhibitor 1C|Gene Expression Regulation, Developmental|Mice, Knockout|Genes, cdc|Cd24a protein, mouse|CD24 Antigen|Tcfeb protein, mouse 19 APMAP 18513186 Biochem. J. 2008 10.1042/BJ20080503 6 0 1 44 Humans|HEK293 Cells|Endothelial Cells|Blotting, Northern|Amino Acid Sequence|Cloning, Molecular|Base Sequence|DNA, Complementary|Membrane Proteins|Sequence Homology, Amino Acid|Chromosome Mapping|Immunoblotting|RNA, Messenger 19 CDKN2AIP 19001376 J. Biol. Chem. 2008 10.1074/jbc.M805778200 14 3 2 154 Humans|*Cellular Senescence|*Apoptosis|Tumor Suppressor Protein p53|Apoptosis Regulatory Proteins|DNA Repair|Fibroblasts|DNA Damage|Cell Line, Tumor|Cell Cycle|Tumor Suppressor Proteins|Signal Transduction|Cell Division 19 DRC1 18948746 Cell Cycle 2008 10.4161/cc.7.21.6932 8 5 1 38 *Merozoite Surface Protein 1|Saccharomyces cerevisiae Proteins|DNA Replication|Saccharomyces cerevisiae|S Phase|Cell Cycle Proteins|DNA, Fungal|Cell Cycle|*Cell Cycle Checkpoints|DNA-Binding Proteins|Cyclin-Dependent Kinases|Cell Division|Protein Binding|CDC14 protein, S cerevisiae|Protein Tyrosine Phosphatases|SLD2 protein, S cerevisiae|DPB11 protein, S cerevisiae|CDC7 protein, S cerevisiae 45 GSDMC 19051310 Genes Chromosomes Cancer 2008 10.1002/gcc.20636 39 0 2 11 Humans|Gastric Mucosa|Gastric Cancers|*Epithelium|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Esophagus|Stomach|*Gastrointestinal Tract, Upper|Gene Expression Profiling|Cell Line, Tumor|Apoptosis|Cell Differentiation|GSDMA protein, human|GSDMD protein, human 19 IFNK 18615156 Mol. Med. 2008 PMC2276142 10.2119/2008-00056.Liu 68 0 4 71 Humans|*Genome-Wide Association Study|*Tumor Necrosis Factor-alpha|*Rheumatoid Arthritis|Antirheumatic Agents|Etanercept|Infliximab|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Antibodies, Monoclonal|Treatment Outcome|Severity of Illness Index|MAFB protein, human|MafB Transcription Factor|Oligonucleotide Array Sequence Analysis|Cohort Studies|Longitudinal Studies|PON1 protein, human|Aryldialkylphosphatase 19 IGSF9 18268009 Mol. Cell. Biol. 2008 PMC2293102 10.1128/MCB.02102-07 8 0 0 96 Mice|Animals|*Synapse|Dendrites|Neurons|Hippocampus|Nerve Tissue Proteins|BDNF protein, human|Brain-Derived Neurotrophic Factor|RNA Interference|Immunoglobulin|Cells, Cultured|Mice, Knockout|*Organogenesis|Neuronal Plasticity 19 IMPG2 19050768 Mol. Vis. 2008 PMC2592529 3 0 0 17 Mice|Animals|*Retinal Degeneration|cis-trans-Isomerases|Retina|Eye Proteins|Carrier Proteins|Membrane Proteins|mRNA 26 PASD1 19107609 Med Mol Morphol 2008 10.1007/s00795-008-0419-6 0 0 0 15 Humans|Mice|Animals|*Genes, ras|Lung Neoplasms|Genetic Susceptibility|ras Proteins|Adenocarcinoma|Alleles|*Carcinogenesis|Mutations|Chromosome Mapping|Genetic Linkage|Adenoma|Cell Transformation, Neoplastic|KRAS protein, human 19 PASD1 18299280 Carcinogenesis 2008 10.1093/carcin/bgn048 9 0 1 15 Humans|Mice|Animals|*Hyperplasia|*Proto-Oncogene Proteins p21(ras)|Case-Control Studies|*K-ras Oncogene|Bronchioloalveolar Carcinoma|*Lung Adenocarcinoma|*Precancerous Conditions|Lung Neoplasms|Adenocarcinoma|ras Proteins|ErbB Receptors|Lungs|*Polymorphism, Genetic|Mutation|Adenomas|KRAS protein, human 19 PCDH12 19054571 Psychiatry Res 2008 10.1016/j.psychres.2007.08.011 18 0 0 30 Humans|Adult|reelin protein|Cell Adhesion Molecules, Neuronal|Serine Endopeptidases|Extracellular Matrix Proteins|*Schizophrenia|Nerve Tissue Proteins|Genetic Predisposition to Disease|Alleles|Gene Frequency|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|Brain|PCDH12 protein, human|Cadherins 27 s100a5 18193636 Subcell. Biochem. 2008 10.1007/978-1-4020-6191-2_5 58 1 3 15 Animals|Humans|Mice|*S100 Proteins|Receptor for Advanced Glycation End Products|EF Hand|Protein Binding|Advanced Glycation Endproducts|Calcium|Signal Transduction|Dimerization|Cancer 39 SERPINA9 18799872 Cerebrovasc. Dis. 2008 PMC2662496 10.1159/000155637 5 0 0 6 Humans|*Stroke|*Polymorphism, Single Nucleotide|*Brain Ischemia|*Coronary Heart Disease|*Atherosclerosis|Whites|Risk Factors|Gene Frequency|African Americans|Genetic Predisposition to Disease|Cox Proportional Hazards Models|Cohort Studies|Prospective Studies 19 SERPINA9 18550480 Am. J. Clin. Pathol. 2008 10.1309/9QKE68QU7B825A3U 2 0 0 6 SERPINA9 protein, human|*Serpins|*Germinal Center|*Neoplasm Proteins|BCL6 protein, human|Proto-Oncogene Proteins c-bcl-6|Lymphoma, Large B-Cell, Diffuse|Lymphomas, Follicular|B Cells|Burkitt Lymphoma|Lymph Node|Immunohistochemistry|*Phenotype|Neprilysin 19 TXNDC12 18628206 J. Biol. Chem. 2008 PMC2533083 10.1074/jbc.M803804200 9 1 0 67 Humans|Animals|*Protein Disulfide Reductase (Glutathione)|HeLa Cells|*Endoplasmic Reticulum Stress|*Endoplasmic Reticulum|Amino Acid Sequence|Protein Disulfide-Isomerases|Thioredoxins|Recombinant Proteins|Redox|Protein Folding|Disulfides|*Apoptosis|Binding Sites|Cysteine|Peptide, Signal|Sequence Homology, Amino Acid|Catalysis 19 wdfy1 18397380 Genes Brain Behav. 2008 10.1111/j.1601-183X.2008.00405.x 29 0 2 79 Animals|Mice|*Mice, Inbred C57BL|*Ethanol|Alcohol-Induced Disorders, Nervous System|*Phenotypes|*Genomics|Alcoholism|Alcohol Consumption|Chromosome Mapping|Genetic Predisposition to Disease|Genotype|Brain|Species Specificity|Disease Models, Animal 19 DRC1 17986766 Biosci. Biotechnol. Biochem. 2007 10.1271/bbb.60587 1 0 0 38 *Lactococcus lactis|*Plasmid|Replicon|Origin, Replication|Base Sequence|DNA, Bacterial|DNA Replication|Amino Acid Sequence|Vector, Shuttle|Escherichia coli|DNA Primers 45 LMOD2 17572376 Arch. Biochem. Biophys. 2007 10.1016/j.abb.2007.05.012 20 2 1 42 *Tropomyosin|Tropomodulin|*Isoforms|Actins|Binding Sites|Protein Binding|Muscle Proteins|Amino Acid Sequence|Carrier Proteins|Skeletal Muscles|Circular Dichroism 19 MYNN 17409414 Cancer Res. 2007 10.1158/0008-5472.CAN-06-2366 57 4 1 15 Humans|Female|*Carcinoma, Ovarian Epithelial|Comparative Genomic Hybridization|Proto-Oncogenes|MDS1 and EVI1 Complex Locus Protein|DNA-Binding Proteins|*Ovarian Cancer|*Myelodysplastic Syndrome|Transcription Factors|Chromosome Aberrations|Leukemia, Myeloid, Acute|Ovary|Transforming Growth Factor beta|Prognosis|MYNN protein, human|Kruppel-Like Transcription Factors 19 rtn2 18096700 J. Biol. Chem. 2007 PMC2581797 10.1074/jbc.M708096200 24 10 1 109 Animals|*Glutamate|*Excitatory Amino Acid Transporter 3|*Neurons|*Protein Transport|Carrier Proteins|Endoplasmic Reticulum|Central Nervous System|Cell Membrane|Membrane Proteins|Brain|*Cell Movement 23 s100a5 17970044 Anticancer Res. 2007 33 0 0 15 Humans|Mice|Rats|Animals|*Urinary Bladder Neoplasms|*S100 Protein Family|Carcinoma, Transitional Cell|Urothelium|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Signal Transduction|Calgranulin B|Calgranulin A|S100A5 protein, human|S100A14 protein, human|Calcium-Binding Proteins|S100A16 protein, human|S100a3 protein, mouse 39 SERPINA9 17898315 Blood 2007 10.1182/blood-2007-06-094151 16 0 0 6 Humans|Adult|SERPINA9 protein, human|*Serpins|*Germinal Center|*Neoplasm Proteins|Lymphoma, Large B-Cell, Diffuse|Follicular Lymphoma|Burkitt Lymphoma|B Cells|Hodgkin Disease|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Mantle Cell Lymphoma|Leukemia, Lymphocytic, Chronic, B-Cell|Cell Line, Tumor|Cell Differentiation 19 SERPINA9 17447896 Biochem. J. 2007 PMC2267310 10.1042/BJ20070174 5 3 0 6 SERPINA9 protein, human|*Serpins|Kinetics|Heparin|*Germinal Center|*Neoplasm Proteins|Serine Proteinase Inhibitors|B Cells|Lymphoma, Large B-Cell, Diffuse|trypsin-like serine protease|Serine Endopeptidases|Cloning, Molecular|Amino Acid Sequence|*Germ Cells|Trypsin|Thrombin 19 wdfy1 17332017 Nucleic Acids Res. 2007 PMC1874599 10.1093/nar/gkm026 15 7 0 79 Humans|*Introns|*Alternative Splicing|*Computational Biology|Spliceosomes|RNA Splicing|RNA, Small Nuclear|RNA Splice Sites|Exon|RNA Precursors|RNA, Messenger|Base Sequence|Mutation 19 IMPG2 16469746 J. Biol. Chem. 2006 10.1074/jbc.M508161200 1 0 0 17 Humans|Animals|Infant, Newborn|Proteoglycan|Sialoglycoproteins|*Cloning, Molecular|*Chickens|Extracellular Matrix Proteins|Chondroitin Sulfates|Retina|Amino Acid Sequence|Hyaluronic Acid|Eye Proteins 26 rtn2 17189258 J. Biol. Chem. 2006 PMC2852886 10.1074/jbc.M609797200 28 7 0 109 *Nogo Receptor 1|*Myelin Sheath|*Ligands|Nogo Proteins|Myelin Proteins|*Neurons|Myelin-Associated Glycoprotein|RTN4RL1 protein, human|Nogo Receptors|Central Nervous System|Receptors, Cell Surface|Ganglia, Spinal|GPI-Linked Proteins|Protein Binding|Cells, Cultured 23 rtn2 16505974 Cell. Mol. Life Sci. 2006 10.1007/s00018-005-5338-2 33 0 1 109 Humans|Animals|*Neurodegenerative Diseases|RTN1 protein, human|Nerve Tissue Proteins|Integral Membrane Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Myelin Proteins|Carrier Proteins|beta Secretase|Intracellular Signaling Peptides and Proteins|Nogo Proteins|Endoplasmic Reticulum|Alzheimer Disease|Cryptic Splice Sites|Gene Expression 23 SERPINA9 16933151 Neurochem. Res. 2006 10.1007/s11064-006-9117-8 4 0 0 6 Mice|Animals|*Mice, Transgenic|Alzheimer Disease|Amyloid beta-Protein Precursor|Amyloid beta-Peptides|*Hippocampus|Peptide Fragments|Oligonucleotide Array|Disease Models, Animal|Up-Regulation|Downregulation|Brain|Behavior, Animal|Phosphopyruvate Hydratase|*Oligonucleotides|mRNA 19 SPATA5 16465403 Int. J. Mol. Med. 2006 15 0 0 119 Humans|Mice|Rats|Animals|*Wnt Signaling Pathway|Hedgehog Proteins|Base Sequence|Bioinformatics|Binding Sites|Sequence Alignment|Amino Acid Sequence|Promoter Regions, Genetic|Genomics|Sequence Homology, Nucleic Acid|Genome, Human|Conserved Sequence|Chimpanzee|fibroblast growth factor 18|Fibroblast Growth Factors|Proteomics|*Progenitor Cells|*Biological Evolution 19 TSPEAR 16407063 Structure 2006 PMC2896259 10.1016/j.str.2005.09.017 34 0 2 2 *Thrombospondin 1|*Heparin|Protein Structure, Tertiary|Binding Sites|Amino Acid Sequence|Crystallography, X-Ray|Protein Binding|Models, Molecular|Glycosaminoglycans|Laminin|Peptide Fragments|Collagen|Cell Adhesion 19 DRC1 15960976 Cell 2005 10.1016/j.cell.2005.05.015 113 1 3 38 Humans|Animals|*Rothmund-Thomson Syndrome|RECQL4 protein, human|*RecQL4 Helicase|DNA Replication|Cell Cycle Proteins|Chromatin|DNA-Binding Proteins|Mutation|Xenopus laevis|DNA 45 IGSF9 15755926 Sci. STKE 2005 10.1126/stke.2742005pe10 2 0 0 96 Mice|Animals|*Synapses|AMPA Receptor|*Neurons|Dendrites|Synaptic Transmission|Neuronal Plasticity|Hippocampus|Glutamic Acid 19 PASD1 16112646 Biochem. Biophys. Res. Commun. 2005 10.1016/j.bbrc.2005.08.024 14 0 2 15 Male|Humans|*Leukemia, Myeloid, Acute|Antigens, Neoplasm|cDNA Library|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Immunotherapy|PCR|T-Lymphocytes|Testis|PASD1 protein, human|Antigens, Nuclear 19 rtn2 15946766 Brain Res. Mol. Brain Res. 2005 10.1016/j.molbrainres.2005.04.020 8 2 1 109 Humans|Mice|Animals|Nerve Tissue Proteins|Membrane Proteins|Myelin Proteins|Carrier Proteins|Protein Isoforms|Intracellular Signaling Peptides and Proteins|Nogo Proteins|Neurons|Alternative Splicing|mRNA|Exon|Cerebellum|Hippocampus|Blotting, Western|Rtn3 protein, mouse|Rtn1 protein, mouse 23 rtn2 15858203 Mol. Biol. Evol. 2005 10.1093/molbev/msi158 13 0 1 109 Animals|*Neurites|RTN4 protein, human|*Nogo Proteins|Axons|Phylogeny|Nerve Regeneration|Myelin Proteins|Zebrafish|Zebrafish Proteins|*Growth Inhibitors|Membrane Proteins|Myelin|Central Nervous System|*Neurogenesis|Synteny 23 rtn2 15765506 Dev. Dyn. 2005 10.1002/dvdy.20327 2 0 0 109 Animals|*Xenopus laevis|Xenopus Proteins|Embryo, Nonmammalian|Amino Acid Sequence|Gene Expression Regulation, Developmental|Sequence Alignment|Sequence Homology, Amino Acid|mRNA|cDNA 23 s100a5 16171556 Cell. Mol. Biol. (Noisy-le-grand) 2005 39 0 0 15 Rats|Mice|Animals|S100 Proteins|*Signal Transduction|Blotting, Northern|mRNA|Amyloid beta-Protein Precursor|Cytoplasm|*Nervous System|S100a3 protein, mouse|S100a6 protein, rat|S100 Calcium Binding Protein A6|Cell Cycle Proteins 39 SERPINA9 16310039 Placenta 2005 10.1016/j.placenta.2004.11.009 3 4 0 6 Humans|Female|Pregnancy|GZMB protein, human|*Granzymes|*Up-Regulation|*Moles, Hydatidiform|Choriocarcinoma|*Placental Development|*Serine Proteinase Inhibitors|Trophoblastic Diseases, Gestational|Placenta|Uterine Neoplasms|yeast proteinase B|Cytotrophoblasts|Serpins|*Transcriptional Activation|Immunohistochemistry|Cell Lines 19 TSPEAR 16205735 Mol. Psychiatry 2005 10.1038/sj.mp.4001759 23 2 1 2 Animals|Mice|*Bipolar Disorder|*TRPM Cation Channels|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Linkage Disequilibrium|Alleles|Haplotypes|Genetic Linkage|Genotype|Microsatellite Markers|Pedigree|Genetic Markers|Exon|DNA|*Chromosome Structures|TRPM2 protein, mouse 19 IGSF9 15340157 Proc. Natl. Acad. Sci. U.S.A. 2004 PMC516568 10.1073/pnas.0405370101 17 0 0 96 Dendrites|Neurons|Hippocampus|Axons|Nerve Tissue Proteins|RNA Interference|*Organogenesis|Cells, Cultured|Brain|Synapses|Neuronal Plasticity 19 IGSF9 15340156 Proc. Natl. Acad. Sci. U.S.A. 2004 PMC516569 10.1073/pnas.0405371101 16 1 0 96 Animals|*Synapses|Synaptic Transmission|Receptors, AMPA|*Immunoglobulin|Dendrites|Neurons|Hippocampus|Nerve Tissue Proteins|Receptors, N-Methyl-D-Aspartate|alpha Amino 3 hydroxy 5 methyl 4 isoxazolepropionic Acid|Neuronal Plasticity 19 IGSF9 15019980 Gene 2004 10.1016/j.gene.2003.12.036 3 0 0 96 Humans|Animals|*mRNA|UTRs|Tandem Repeats, Short|Nucleic Acid Conformation 19 IMPG2 15044457 J. Biol. Chem. 2004 10.1074/jbc.M401584200 4 1 0 17 Mice|Animals|*Glycosaminoglycans|*Hyaluronic Acid|Amino Acid Sequence|Extracellular Matrix Proteins|Hyaluronan Receptors|Heparin|Chondroitin Sulfates|Binding Sites|Heparan Sulfate Proteoglycans|Carrier Proteins|Recombinant Proteins|Extracellular Matrix|Cell Movement 26 MYNN 15276997 Avian Pathol. 2004 10.1080/0307945042000195768 21 0 2 15 Animals|*Newcastle disease virus|*Columbidae|Phylogeny|Newcastle Disease|*Molecular Epidemiologies|Viral Fusion Proteins|Amino Acid Sequence|RNA, Viral|Geography|*DNA Viruses|Iraq 19 PASD1 15162151 Br. J. Cancer 2004 PMC2364759 10.1038/sj.bjc.6601875 10 3 1 15 Humans|Male|*Testis|*Lymphoma, Large B-Cell, Diffuse|PASD1 protein, human|Antigens, Neoplasm|Antigens, Nuclear|*Protein Domain|Immunophenotyping|Neprilysin|Transcription Factor|cDNA|mRNA|BCL6 protein, human|Proto-Oncogene Proteins c-bcl-6 19 rtn2 15286784 Nat. Med. 2004 10.1038/nm1088 101 4 5 109 Humans|APP protein, human|*Amyloid beta-Protein Precursor|*beta-Peptide, Amyloid|*Amyloid Precursor Protein Secretases|*Aspartic Acid Endopeptidases|Amyloid Plaques|Alzheimer Disease|Nerve Tissue Proteins|Membrane Proteins|Carrier Proteins|RTN4 protein, human|Nogo Proteins|Peptide Fragments|Neurons|Brain|BACE1 protein, human 23 TSPEAR 15028290 Genomics 2004 10.1016/j.ygeno.2003.09.024 8 0 2 2 Humans|Animals|*Introns|Amino Acid Sequence|Gene Cluster|*Cytoskeletal Proteins|Base Sequence|Keratins, Hair-Specific|Hair|Sequence Homology, Amino Acid|Chromosome Mapping|*Human Chromosome|DNA, Complementary|Phylogeny|Pseudogenes|TSPEAR protein, human|Proteins 19 MYNN 14694499 Muscle Nerve 2003 10.1002/mus.10526 8 0 2 15 Humans|Mice|Animals|Neuromuscular Junctions|*Zinc Finger|*Cytoskeletal Proteins|Muscle Fibers, Skeletal|Synaptic Membranes|Muscle, Skeletal|Synaptic Transmission|Receptors, Nicotinic 19 MYNN 12850913 Avian Pathol. 2003 10.1080/030794503100009783 62 0 0 15 Animals|*Newcastle disease virus|*Base Sequence|*Phylogeny|Newcastle Disease|Viral Fusion Proteins|Sequence Alignment|Amino Acid Sequence|Chickens|Genotype|*Epidemiological Study|Sequence Analysis, DNA|Geography 19 PLCL2 14517301 Mol. Cell. Biol. 2003 PMC230318 10.1128/mcb.23.20.7329-7338.2003 17 0 0 21 Mice|Animals|*Signal Transduction|Adaptor Proteins, Signal Transducing|Receptors, Antigen, B-Cell|Phosphoproteins|Nuclear Proteins|Phospholipase C gamma|DNA-Binding Proteins|Carrier Proteins|Protein-Tyrosine Kinases|Phosphorylation|Mitogen-Activated Protein Kinases|Intracellular Signaling Peptides and Proteins|Membrane Proteins|NFATC Transcription Factors|B Cells|Syk Kinase|Lipase 19 rtn2 14664809 Mol. Cell. Neurosci. 2003 10.1016/s1044-7431(03)00199-4 30 0 2 109 Humans|Animals|Mice|Nogo Proteins|Nogo Receptor 1|Central Nervous System|Myelin-Associated Glycoprotein|Myelin|Oligodendrocytes|*Systems, Peripheral Nervous|Axons|Receptors, Cell Surface|Neurons|Nerve Regeneration|Ligands|GPI-Linked Proteins|Myelin-Oligodendrocyte Glycoprotein|*Mammals|p75, Neurotrophin Receptor|mRNA|Signal Transduction 23 SERPINA9 12819018 Am. J. Pathol. 2003 PMC1868163 10.1016/S0002-9440(10)63637-1 13 1 0 6 Mice|Animals|*Germinal Center|*B Cells|Lymphoma, Large B-Cell, Diffuse|Follicular Lymphoma|Neoplasm Proteins|Serpins|Lymphocyte Activation|Amino Acid Sequence 19 TXNDC12 14557066 Gene 2003 10.1016/s0378-1119(03)00732-7 8 0 0 67 Mice|Animals|Chlorocebus aethiops|Humans|cDNA|TXN protein, human|Thioredoxin|Blotting, Northern|Sequence Alignment|Amino Acid Sequence|Cloning, Molecular|Base Sequence|Exons|Introns|Sequence Homology, Amino Acid|RNA, Messenger|Immunoblotting|Green Fluorescent Proteins|Sequence Analysis, DNA|COS Cells 19 TXNDC12 12930873 Mol. Cell Proteomics 2003 10.1074/mcp.M300053-MCP200 27 0 0 67 Proteomics|TXN protein, human|*Thioredoxin|Protein Disulfide-Isomerases|*Endoplasmic Reticulum|Amino Acid Sequence|Blotting, Northern|Blotting, Western|Sequence Homology, Amino Acid|mRNA 19 TXNDC12 12761212 J. Biol. Chem. 2003 10.1074/jbc.M304598200 24 0 0 67 Humans|TXN protein, human|*Thioredoxin|Protein Disulfide-Isomerases|*Endoplasmic Reticulum|Protein Folding|Disulfides|Oxidation-Reduction|Amino Acid Sequence|Cysteine|Protein Conformation|Binding Sites|Catalysis|Circular Dichroism|Kinetics|Catalytic Domain|Peptides|Membrane Proteins 19 GSDMC 12168807 Histol. Histopathol. 2002 10.14670/HH-17.951 4 0 0 11 Humans|Mice|Animals|B16 Melanoma|*Neoplastic Processes|Tumor Cell Lines|*Disease Models, Animal|cDNA Libraries|Carcinogenesis|Lung Neoplasms|Gene Expression 19 IGSF9 11991715 Genomics 2002 10.1006/geno.2002.6757 13 0 0 96 Mice|Animals|Humans|Drosophila melanogaster|tutl protein, Drosophila|*Immunoglobulin|In Situ Hybridization|Membrane Proteins|Amino Acid Sequence|Sequence Alignment|Nerve Tissue Proteins|DNA, Complementary|Base Sequence|Cloning, Molecular|Blotting, Northern|Gene Expression Regulation, Developmental|Embryo, Mammalian|Chromosome Mapping|Neural Cell Adhesion Molecule|Sequence Homology, Amino Acid|Gene Expression Profiling 19 APMAP 11583587 Biochem. J. 2001 PMC1222159 10.1042/0264-6021:3590393 5 1 0 44 Mice|Animals|*Integral Membrane Protein|Adipocyte|*Cell Differentiation|cDNA|3T3-L1 Cells|mRNA|Blotting, Northern|Amino Acid Sequence|Plasma Membrane|Adipose Tissue|Cloning, Molecular|Display, mRNA Differential|Sequence Homology, Amino Acid|Amino Acids|Transcription Factors|Transfection|Subcellular Fractions 19 GSDMC 11223543 Jpn. J. Cancer Res. 2001 PMC5926699 10.1111/j.1349-7006.2001.tb01076.x 16 0 1 11 Humans|Mice|Animals|In Situ Hybridization, Fluorescence|Melanoma, Cutaneous Malignant|Skin Neoplasms|*Chromosome Mapping|B16 Melanoma|Neoplasm Proteins|Gene, c-myc|Amino Acid Sequence|Gene Expression Regulation, Neoplastic|Base Sequence|cDNA Library|Cloning, Molecular|mRNA|DNA, Complementary|Tumor Cells, Cultured|Blotting, Northern 19 LMOD2 11318603 Genomics 2001 10.1006/geno.2000.6501 60 0 3 42 Humans|Mice|Animals|*Tropomodulin|Microfilament Proteins|Actin Filament|Actins|Muscle Proteins|Amino Acid Sequence|Carrier Proteins|Protein Binding|Isoforms|Intron|Exon|Sequence Homology, Amino Acid|Muscle, Skeletal|RNA, Messenger|leiomodin 2 protein, human 19 slamf8 11313408 J. Immunol. 2001 10.4049/jimmunol.166.9.5675 18 0 1 45 Mice|Animals|*Macrophage|*B-Lymphocytes|FCER2 protein, human|Lectins, C-Type|Dendritic Cells|Amino Acid Sequence|Membrane Glycoproteins|Lymphocyte Activation|Base Sequence|Signaling Lymphocytic Activation Molecule Family|Cloning, Molecular|CD2 Antigens|Antigen Presentation|DNA, Complementary|Lymphoid Tissue|Sequence Homology, Amino Acid|Cells, Cultured|Cell Surface Proteins 19 MYNN 10873615 Biochem. Biophys. Res. Commun. 2000 10.1006/bbrc.2000.2862 6 0 3 15 Humans|Animals|Mice|*Zinc Finger|Transcription Factors|DNA-Binding Proteins|Amino Acid Sequence|Repressor Proteins|Base Sequence|*Muscle|Gene Expression Regulation|Cell Nucleus|DNA, Complementary|Sequence Homology, Amino Acid|RNA, Messenger|Activation, Transcriptional|*Cytoskeletal Proteins|Embryo, Mammalian 19 rtn2 10672514 J. Muscle Res. Cell. Motil. 2000 10.1023/a:1005533013926 4 0 0 109 Animals|*Sarcomeres|Muscle Proteins|Muscle, Skeletal|Myofibrils|Connectin|plasma protein Z|*Blood Proteins|Green Fluorescent Proteins|alpha Actinin|Myotubes|FABP1 protein, human|*Fatty Acid-Binding Proteins|Luminescent Proteins|Myocardium|Chickens|Amino Acid Sequence|Transfection 23 SERPINA9 11069088 Eur. J. Immunol. 2000 10.1002/1521-4141(200010)30:10<3039::AID-IMMU3039>3.0.CO;2-H 11 4 2 6 Humans|SERPINA9 protein, human|*Serpins|*Germinal Center|*Neoplasm Proteins|*B Cells|Lymphoma, B-Cell|Burkitt Lymphoma|Lymphoma, Follicular|Lymphocyte Activation|Serine Protease Inhibitors|Cell Line, Tumor 19 PLCL2 10581172 Biochem. Biophys. Res. Commun. 1999 10.1006/bbrc.1999.1784 18 2 0 21 Animals|Chlorocebus aethiops|*Phospholipase C|*Phospholipase|Inositol 1,4,5-Trisphosphate|Amino Acid Sequence|Phospholipase C delta|Protein Binding|Binding Sites|Region, Catalytic|Kinetics|Isoenzymes|Sequence Homology, Amino Acid|Phosphoproteins|Cell Membrane|COS-7 Cells|Models, Molecular|Endoplasmic Reticulum 19 APMAP 2100416 Urol. Res. 1990 10.1007/BF00297373 1 0 0 44 *Struvite|*Crystallization|Renal Dialysis|Magnesium Compounds|Phosphate|Calcium Oxalate|Urinary Calculi|Magnesium|Hydrogen-Ion Concentration|Macromolecular Substances|*Body Fluids 19 ???? 32674225 Int. J. Cancer 2020 10.1002/ijc.33215 0 0 0 0 *Consensus|Medical Oncology|Cancers 20720342 ???? 32674223 J Am Geriatr Soc 2020 10.1111/jgs.16752 0 0 0 0 United States|Humans|*Skilled Nursing Facilities|COVID-19|severe acute respiratory syndrome coronavirus 2|*SARS-CoV|*Prevalence|Pandemics|Pneumonia, Viral|Coronavirus Infections|Betacoronavirus|Long-Term Care|Patient Discharge|Medicare|Outbreaks 20720342 ???? 32674222 Child Adolesc Ment Health 2020 10.1111/camh.12402 0 0 0 0 Child|Adolescent|Humans|COVID-19|*Mental Health|severe acute respiratory syndrome coronavirus 2|*Mental Disorders|Pandemic|Coronavirus Infections|Pneumonia, Viral|Anxiety|Cognitive Behavioral Therapy|Depression|Betacoronavirus|Telemedicine|Mental Health Services 20720342 ???? 32674220 Int. J. Cancer 2020 10.1002/ijc.33210 0 0 0 0 *Digestive System Neoplasms|*Gastrointestinal Neoplasms 20720342 ???? 32674218 Biochem Mol Biol Educ 2020 10.1002/bmb.21401 0 0 0 0 Humans|COVID-19|severe acute respiratory syndrome coronavirus 2|*Thinking Skills|Coronavirus Infections|Pandemic|Problem-Based Learning|Students, Nursing|Curriculum|Mentor|Videotape Recording 20720342 ???? 32674217 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|COVID-19|severe acute respiratory syndrome coronavirus 2|Coronavirus Infection|Pandemic|Betacoronavirus|Pneumonia, Viral|*Medical Oncology|Coronavirus|Quarantine|*Telemedicine|Cancer|Public Health 20720342 ???? 32674216 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|*Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|CD274 protein, human|B7-H1 Antigen|*Immunotherapy|CTLA4 protein, human|CTLA-4 Antigen|Programmed Cell Death 1 Receptor|Nivolumab|*Immunologic Factors|Small Cell Lung Carcinoma|Melanoma|Antibodies, Monoclonal, Humanized 20720342 ???? 32674215 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|severe acute respiratory syndrome coronavirus 2|COVID-19|*Psycho-Oncology|*Psychological Distress|Betacoronavirus|Pneumonia, Viral|Coronavirus Infections|*Pandemic|Medical Oncology|Cancer|Providers, Healthcare|*Emotions 20720342 ???? 32674214 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|COVID-19|severe acute respiratory syndrome coronavirus 2|*Pandemic|*Coronavirus|Pneumonia, Viral|*Coronavirus Infection|Betacoronavirus|*Medical Oncology|Quarantine|*Cancer|Public Health 20720342 ???? 32674213 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|axicabtagene ciloleucel|Immunotherapy, Adoptive|Antigens, CD19|Lymphoma, Non-Hodgkin|Lymphoma, Large B-Cell, Diffuse|Antineoplastic Combined Chemotherapy Protocols 20720342 ???? 32674212 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|*Multiple Myeloma|carfilzomib|*Progression-Free Survival|Lenalidomide|*Oligopeptides|Bortezomib|Thalidomide|Dexamethasone|Disease-Free Survival|Antineoplastic Combined Chemotherapy Protocols 20720342 ???? 32674211 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|tivozanib|*Carcinoma, Renal Cell|Kidney Neoplasms|*Data Analysis|*Phenylurea Compounds|*Quinolines|Sorafenib|Protein Kinase Inhibitors|Receptors, Vascular Endothelial Growth Factor 20720342 ???? 32674210 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 *Gastrointestinal Cancer|Medical Oncology|Societies, Medical 20720342 ???? 32674209 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|*Nonsmall Cell Lung Cancer|*Nivolumab|*Ipilimumab|Lung Neoplasms|CD274 protein, human|B7-H1 Antigen|Antineoplastic Agents, Immunological|Antineoplastic Combined Chemotherapy Protocols|Mutation 20720342 ???? 32674208 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|Male|*Leuprolide|relugolix|*Prostate Cancer|*Phenylurea Compounds|*Pyrimidinones|Prostate-Specific Antigen|Antineoplastic Agents, Hormonal|Testosterone 20720342 ???? 32674207 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|Female|mirvetuximab soravtansine|*Maytansine|*Carcinoma, Ovarian Epithelial|*Immunoconjugates|*Antibodies, Monoclonal, Humanized|*Ovarian Cancer|Folate Receptor 1|Drug Resistance, Neoplasm|Bevacizumab|Platinum 20720342 ???? 32674206 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|severe acute respiratory syndrome coronavirus 2|COVID-19|Betacoronavirus|Pneumonia, Viral|Pandemics|Coronavirus Infections|Azythromycin|Hydroxychloroquine|*Neoplastic Processes|Risk Factors|Treatment Outcome|Drug Administration Schedule|Antiviral Agents|Time Factors|Cancer|COVID-19 drug treatment 20720342 ???? 32674205 Oncology (Williston Park, N.Y.) 2020 0 0 0 0 Humans|COVID-19|*Coronavirus|*Pandemic|severe acute respiratory syndrome coronavirus 2|Pneumonia, Viral|*Coronavirus Infections|Betacoronavirus|Medical Oncology|Telemedicine 20720342 ADTRP 32445923 Gene 2020 10.1016/j.gene.2020.144805 0 0 0 78 *Coronary Artery Disease|lipoprotein-associated coagulation inhibitor|*Transcription Factor|*Gene Expression Regulation|Lipoproteins|Response Element|Atherosclerosis|*Genes, Homeobox|Endothelial Cell|Promoter Regions, Genetic|Membrane Proteins|Chromatin Immunoprecipitation|Transcription Start Site|Myelopoiesis|Upregulation|Binding Site|Case-Control Studies 18 ADTRP 32237974 J Am Heart Assoc 2020 10.1161/JAHA.119.014146 0 0 0 78 Humans|*Genome-Wide Association Study|*Epistasis, Genetic|*Cardiovascular Diseases|*Risk Factors|*Genomics|Genetic Predisposition to Disease|Coronary Artery Disease|Polymorphism, Single Nucleotide|Gene Expression Regulation|RNA, Long Noncoding|Gene Expression Profiling|Phenotypes|*Cardiovascular System 18 ADTRP 32152231 J. Biol. Chem. 2020 PMC7196635 10.1074/jbc.RA119.012145 0 0 0 78 Mice|Animals|*Esters|lipoprotein-associated coagulation inhibitor|*Hydrolases|*Fatty Acids|Chromatography, Liquid|*Lipoproteins|Mass Spectrometry|Lipids|*Androgens|*Gene Expression|*Transcription Factors|AIG1 protein, mouse|Membrane Proteins 18 CAMK1G 32546599 Ann. Rheum. Dis. 2020 10.1136/annrheumdis-2019-216599 0 0 0 35 Humans|*Transcriptome|Antisynthetase syndrome|*Myositis|Inclusion Body Myositis|Polymyositis|Dermatomyositis|Autoimmune Diseases|Autoantibodies|Muscle, Skeletal|*Machine Learning|*Algorithms|Necrosis|*Biopsy 18 CAMK1G 32509861 Biomed Res Int 2020 PMC7251429 10.1155/2020/5019793 0 0 0 35 Humans|Male|Aged|*Prognosis|*Prostate|*Oncogenes|Gene Regulatory Networks|Gene Ontology|*Prostatic Neoplasms|Protein Interaction Maps|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Computational Biology|Biomarkers, Tumor|Adenocarcinoma|Tumor Microenvironment 18 CDHR5 32651463 Sci Rep 2020 PMC7351711 10.1038/s41598-020-68325-3 0 0 0 51 Humans|*Subarachnoid Hemorrhage|*B-DNA|*DNA Methylation|*Brain Ischemia|Vasospasm, Intracranial|*Cerebral Infarction|Epigenesis, Genetic 19 chorea 32670106 Front Psychiatry 2020 PMC7328706 10.3389/fpsyt.2020.00564 0 0 0 0 Child|Humans|*Chorea|*Autoantibodies|*Autoimmune Diseases|*Streptococcal Infections|*Basal Ganglia|*Encephalitis|Dopamine Receptor|Immunoglobulin G|Obsessive-Compulsive Disorder|*Biomarkers|Neurons 13074 chorea 32662046 J. Mol. Neurosci. 2020 10.1007/s12031-020-01654-0 0 0 0 0 Humans|Child|Adolescent|Young Adult|Adult|Middle Aged|*Hepatolenticular Degeneration|*Movement Disorders|*Magnetic Resonance Imaging|Oxidative Stress|Tremor|Malondialdehyde|Glutathione|IL10 protein, human|IL10|Antioxidants|Putamen|Chorea|Globus Pallidus|Dystonia|*Biomarkers|Cytokines|Glutamate|Copper 13074 chorea 32643304 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2020 10.1002/ajmg.b.32810 0 0 0 0 Adult|Humans|*Huntington Disease|Caudate Nucleus|Atrophy|*Cohort Studies|Putamen|Trinucleotide Repeats|Magnetic Resonance Imaging|Nucleus Accumbens|Onset Age|Disease Progression|Phenotypes|*Asians 13074 chorea 32642387 Cureus 2020 PMC7336583 10.7759/cureus.8483 0 0 0 0 Humans|*Chorea|Hyperglycemia|Dyskinesias|Magnetic Resonance Imaging|Basal Ganglia|Haloperidol|Insulin 13074 chorea 32627162 Rev Neurol 2020 10.33588/rn.7102.2020154 0 0 0 0 Child|Humans|Child, Preschool|*Dyskinesias|Choreiform Movements|Movement Disorders|Dystonic Disorders|Dystonia|Pedigree|Myoclonus|Mutation|Adenylyl Cyclases 13074 chorea 32611460 Cardiol Young 2020 10.1017/S1047951120001596 0 0 0 0 Child|Humans|Retrospective Studies|Turkey|*Acute Rheumatic Fever|Rheumatic Heart Disease|Mitral Valve|Carditis|Aortic Valve Insufficiency|Mitral Valve Insufficiency|Sydenham Chorea|Aortic Valve|Acute Disease|Incidence|Annular Erythema|Erythema 13074 chorea 32606521 Ann Indian Acad Neurol 2020 PMC7313556 10.4103/aian.AIAN_612_19 0 0 0 0 Child|Humans|*Movement Disorders|*Metabolic Diseases 13074 chorea 32580238 Brain Pathol. 2020 10.1111/bpa.12872 0 0 0 0 Humans|*Huntington Disease|*Spinocerebellar Ataxias|SAFB protein, human|*Nuclear Matrix-Associated Proteins|*Matrix Attachment Region Binding Proteins|*Receptors, Estrogen|Purkinje Cell|Cerebellum|Corpus Striatum|Neurons|Nerve Tissue Proteins|Parkinson Disease|RNA Binding Protein|RNA Splicing 13074 chorea 32566771 eNeurologicalSci 2020 PMC7296341 10.1016/j.ensci.2020.100246 0 0 0 0 Child|Humans|Female|Child, Preschool|*Chorea|Saudi Arabia|Fever, Rheumatic|Carditis|Heart Valve Diseases|Echocardiography|Doppler Echocardiography|Antibiotic Prophylaxis 13074 chorea 32558415 Turk. 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Pediatr. 2020 10.24953/turkjped.2020.03.008 0 0 0 0 *Fever, Rheumatic|Rheumatic Heart Disease|Mitral Valve Insufficiency|Echocardiography, Doppler|Myocarditis|Acute Disease|Egypt 13074 chorea 32557468 Fortschr Neurol Psychiatr 2020 10.1055/a-1124-0060 0 0 0 0 *Chorea|*Huntington Disease|Genetic Testing|Movement Disorders 13074 chorea 32549949 Neurohospitalist 2020 PMC7271625 10.1177/1941874420902875 0 0 0 0 Humans|Male|*Chorea|Hyperglycemia|Magnetic Resonance Imaging|*Atrophy|Diabetes Mellitus, Type 2|*Temporal Lobe|Blood Glucose|Tomography, X-Ray Computed|*Dementia|Corpus Striatum 13074 chorea 32526745 Cardiology 2020 10.1159/000508035 0 0 0 0 Child|Humans|*Myocarditis|*Incidence|*Rheumatic Heart Disease|Acute Rheumatic Fever|Mitral Valve Insufficiency|Mitral Valve|Aortic Valve Insufficiency 13074 chorea 32513333 BJPsych Bull 2020 10.1192/bjb.2020.51 0 0 0 0 Humans|Female|*Electroconvulsive Therapy|*Huntington Disease|*Chorea|*Depressive Disorder, Major|*Psychosis|Treatment Outcome|Psychomotor Disorders 13074 chorea 32494755 Neurol Genet 2020 PMC7217656 10.1212/NXG.0000000000000426 0 0 0 0 Humans|*Neuroacanthocytosis|Vesicular Transport Proteins|*Phenotypic Variability|Sweden 13074 chorea 32482839 Neurology 2020 10.1212/WNL.0000000000009649 0 0 0 0 Humans|Gait Disorders, Neurologic|Parkinson Disease|*Gait|Dystonic Disorders|Dystonia|Walking 13074 chorea 32481362 Medicine (Baltimore) 2020 10.1097/MD.0000000000019801 0 0 0 0 *Chorea|*Hyperglycemia|Diabetes Mellitus, Type 2|Dyskinesias 13074 chorea 32454050 Pharmacol. Ther. 2020 10.1016/j.pharmthera.2020.107580 0 0 0 0 *Hyperkinesis|valbenazine|Tetrabenazine|Tardive Dyskinesia|Vesicular Monoamine Transport Proteins|Adrenergic Uptake Inhibitors|Huntington Disease|Antipsychotic Agents|Valine|Chorea|Dopamine Antagonists|Involuntary Movements|Neurotransmission|Personality 13074 CHURC1 32378051 Breast Cancer Res. Treat. 2020 10.1007/s10549-020-05603-8 0 0 0 49 *Capecitabine|Quality of Life|Hand-Foot Syndrome|Fluorouracil|Antimetabolites, Antineoplastic|Deoxycytidine|Polymorphism, Single Nucleotide|Pharmacogenetics|*Germ Line 18 CNTNAP5 32115622 J. Anim. Sci. 2020 PMC7097718 10.1093/jas/skaa068 0 0 0 24 Cattle|Animals|Genome-Wide Association Study|*Body Size|Quantitative Trait Loci|Haplotype|Single Nucleotide Polymorphisms|Phenotype|Chromosomes 18 CNTNAP5 32077919 Cardiovasc. Res. 2020 10.1093/cvr/cvaa045 0 0 0 24 Humans|*Genome-Wide Association Study|*Coronary Artery Disease|*Diabetes Mellitus, Type 1|*beta-Defensins|Genetic Loci|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genotype|Case-Control Studies|Diabetes Mellitus, Type 2|Risk Factor 18 CNTNAP5 32066700 Transl Psychiatry 2020 PMC7026056 10.1038/s41398-020-0737-6 0 0 0 24 Humans|*Bipolar Disorder|*Genome-Wide Association Study|*Serum|*Biomarkers|CCL2 protein, human|Monocyte Chemoattractant Protein-1|Alzheimer Disease|TIMP1 protein, human|TIMP-1|TIMP2 protein, human|TIMP-2|CXCL8 protein, human|Interleukin-8 18 CPXM2 32562953 Blood Cells Mol. Dis. 2020 10.1016/j.bcmd.2020.102458 0 0 0 18 Female|Humans|Pregnancy|*Transcriptome|*Trophoblasts|Case-Control Studies|*Cell Disease, Sickle|Hemoglobin, Sickle|Hemoglobin SC Disease|*Placenta|*Inflammation|Hemolysis|Erythrocytes|Gene Expression Regulation|*Cell Differentiation|Sickle Cell Trait 18 CPXM2 32492250 Dev. Dyn. 2020 10.1002/dvdy.211 0 0 0 18 18 CPXM2 32280274 Cancer Manag Res 2020 PMC7127851 10.2147/CMAR.S228984 0 0 0 18 18 DNAH1 32622824 Chest 2020 10.1016/j.chest.2020.06.045 0 0 0 6 Child|Humans|Kartagener Syndrome|Homozygote|Cilia|Mutation|China 38 DNAH1 32124190 J. Assist. Reprod. Genet. 2020 PMC7183039 10.1007/s10815-020-01721-w 0 0 0 6 Pregnancy|Male|Humans|Female|*Sperm Injections, Intracytoplasmic|*Pregnancy Outcome|Infertility, Male|Sperm Tail|Pregnancy Rate|Spermatozoa|*Mutations|SPAG6 protein, human|Microtubule Proteins 38 DNAH1 32051257 J. Med. 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Med. 2020 10.1007/s00109-020-01929-4 0 0 0 93 Humans|Mice|Animals|*Neural Crest|*Congenital Heart Defect|*Mesoderm|Heart|Transcription Factor|Embryo, Mammalian|Myocardium|Organogenesis|Signal Transduction|Cell Proliferation 95 MESP2 32518573 J Family Reprod Health 2020 PMC7264868 0 0 0 93 Humans|Jarcho-Levin syndrome|*Hernia, Diaphragmatic|*Abnormalities, Multiple|Spine|Ribs|Dysostosis|Syndrome|Genes, Recessive 95 MESP2 32238941 Nature 2020 10.1038/s41586-020-2144-9 0 0 0 93 Humans|Somites|Embryogenesis|Body Patterning|*Pluripotent Stem Cells|Mesoderm|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|Biological Clocks|Signal Transduction|Glycosyltransferases 95 Mgp 32636682 Cancer Manag Res 2020 PMC7335306 10.2147/CMAR.S251622 0 0 0 556 Humans|Female|*Computational Biology|*Drug Resistance, Neoplasm|Gene Ontology|*Ovarian Cancer|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Protein Interaction Maps|Gene Regulatory Networks|Prognosis|Databases, Genetic|Biomarkers, Tumor|*Cystadenocarcinoma, Serous 1367 Mgp 32605663 Microbiome 2020 PMC7329523 10.1186/s40168-020-00875-0 0 0 0 556 *Microbiomes|Future|Survey 1367 Mgp 32602245 Acta Ophthalmol 2020 10.1111/aos.14533 0 0 0 556 Humans|Corneal Dystrophy, Crystalline, of Schnyder|matrix Gla protein|*Vitamin K|*Corneal Dystrophies, Hereditary|*Extracellular Matrix Proteins|*Calcium-Binding Proteins|*Cornea|Dimethylallyltranstransferase|Pedigree 1367 Mgp 32592049 Environ Sci Pollut Res Int 2020 10.1007/s11356-020-09778-x 0 0 0 556 Female|*Greenhouse Gases|*Farms|Iran|Greenhouse Effect|Dairying|Lactation|Agriculture|Gases|Environmental Pollution 1367 Mgp 32584873 PLoS ONE 2020 PMC7316322 10.1371/journal.pone.0235122 0 0 0 556 Humans|*Stroke|*Brain Ischemia|matrix Gla protein|Retrospective Studies|*Extracellular Matrix Proteins|*Calcium-Binding Proteins|*Recurrence|Single Nucleotide Polymorphism|Cerebral Infarction|Risk Factors|Alleles|Genotype|Cohort Studies|Northeastern United States 1367 Mgp 32551343 Data Brief 2020 PMC7289741 10.1016/j.dib.2020.105765 0 0 0 556 Humans|Colorectal Cancer|Gene Expression Regulation, Neoplastic|HCT116 Cells|Calcium-Binding Proteins|Adenocarcinoma|Colonic Neoplasms|Extracellular Matrix Proteins|Cell Proliferation|Cell Line, Tumor|Transcription Factors 1367 Mgp 32528798 Global Spine J 2020 PMC7263331 10.1177/2192568219879114 0 0 0 556 Humans|*Spine|*Surgery, Minimally Invasive|Low Back Pain|Exercise Therapy 1367 Mgp 32506856 J Tradit Chin Med 2020 10.19852/j.cnki.jtcm.2020.03.010 0 0 0 556 Female|Humans|Rats|Animals|*Osteoporotic Fractures|osteoking|Osteoporosis|*Drugs, Chinese Herbal|Bone Density|Ovariectomy|Osteogenesis|*Downregulation 1367 Mgp 32473013 Gigascience 2020 PMC7260996 10.1093/gigascience/giaa057 1 0 0 556 Cattle|Animals|*Rumen|*Biomass|Metagenome|Microbiota|*Genes, Microbial|Metagenomics|Bacteria|Ruminant 1367 Mgp 32455759 Int J Environ Res Public Health 2020 PMC7277898 10.3390/ijerph17103624 0 0 0 556 Scenedesmus|Phosphorus|Eutrophication|Chlorophyll|Salinity|Water Pollutants, Chemical|Proline 1367 Mgp 32422228 Clin. Biochem. 2020 10.1016/j.clinbiochem.2020.05.005 0 0 0 556 Humans|*Vitamin K|*Cardiovascular Diseases|*Risk Factors|matrix Gla protein|*Extracellular Matrix Proteins|*Calcium-Binding Proteins|*Biomarkers|Vascular Calcification|Vascular Stiffness|*Cardiovascular System 1367 Mgp 32421400 Environ Technol 2020 10.1080/09593330.2020.1771433 0 0 0 556 *Waste Water|*Flocculation|Waste Disposal, Fluid|Water Purification|Industrial Waste|Water Pollutants, Chemical|Ferric Compounds 1367 Mgp 32417474 Sci. Total Environ. 2020 10.1016/j.scitotenv.2020.139002 0 0 0 556 *Coal Ash|*Zeolites|*Fertilizers|*Phosphate|Waste Water|Waste Disposal, Fluid|*Water|Adsorption|Water Pollutants, Chemical 1367 Mgp 32405535 Mol Ther Oncolytics 2020 PMC7210384 10.1016/j.omto.2020.04.005 0 0 0 556 matrix Gla protein|*Up-Regulation|*Calcium Signaling|*Extracellular Matrix Proteins|*Calcium-Binding Proteins|*Transcriptional Activation|Calcinosis|Cells, Cultured|Cell Proliferation|*Colon Cancer 1367 Mgp 32391368 Front Med (Lausanne) 2020 PMC7193028 10.3389/fmed.2020.00154 0 0 0 556 Humans|matrix Gla protein|*Vitamin K|*Extracellular Matrix Proteins|*Calcium-Binding Proteins|*Vascular Calcification|*Chronic Kidney Disease|Renal Dialysis|Calcification, Physiologic 1367 Mgp 32386298 Database (Oxford) 2020 PMC7211034 10.1093/database/baaa029 0 0 0 556 Animals|*Ctenophora|*Data Visualization|*Genome|Evolution, Molecular|Base Sequence|*Gene Expression|*Biochemical Phenomena|Atlantic Ocean 1367 Mgp 32375813 Diagn Pathol 2020 PMC7203875 10.1186/s13000-020-00964-6 0 0 0 556 Humans|Female|*Human Papilloma Virus|*Papillomavirus Infections|Early Detection of Cancer|Uterine Cervical Neoplasms|*Genotype|*Nanopore Sequencing|Genotyping Techniques|DNA, Viral|Sequencing, Next-Generation|Polymerase Chain Reaction|Sensitivity and Specificity|Europe 1367 Mgp 32375689 BMC Cancer 2020 PMC7203972 10.1186/s12885-020-06888-0 0 0 0 556 Female|Humans|*Human Papilloma Virus|*Papillomavirus Infections|*Early Detection of Cancer|*Uterine Cervical Neoplasms|*Genotype|Cervical Intraepithelial Neoplasia|*Cervix Uteri|*Screening|DNA, Viral|Genotyping Techniques|Sensitivity and Specificity|Reproducibility of Results 1367 MIR193A 32316697 Cells 2020 PMC7226544 10.3390/cells9041004 0 0 0 1 Humans|*Podocytes|*Phenotype|Apolipoprotein L1|Transcription Factors|Receptors, Calcitriol|APOL1 protein, human 18 MIR193A 32002372 Adv Pharm Bull 2020 PMC6983996 10.15171/apb.2020.017 1 0 0 1 18 MMRN2 32291340 Proc. 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U.S.A. 2020 PMC7196765 10.1073/pnas.1922713117 0 0 0 55 Animals|Mice|Astrocytes|Neural Stem Cells|Cell Differentiation|Glial Fibrillary Acidic Protein|Neurons|Cells, Cultured|Brain 18 MMRN2 32175193 PeerJ 2020 PMC7058105 10.7717/peerj.8696 0 0 0 55 Humans|*Prognosis|elastin microfibril interface located protein|multimerin|*Glioma|*Membrane Glycoproteins|*Blood Proteins|Isocitrate Dehydrogenase|Brain Neoplasms|Gene Expression Profiling|Mutation|Kaplan-Meier Estimate|Biomarkers, Tumor|Disease-Free Survival|Bioinformatics 18 MMRN2 32166015 Pulm Circ 2020 PMC7052475 10.1177/2045894020908782 0 0 0 55 Humans|Endothelial Cells|*Pulmonary Arterial Hypertension|*Idiopathic Pulmonary Arterial Hypertension|Smooth Muscle Cells|Pericyte|Hypertension, Pulmonary|*Lung|Pulmonary Artery|Cells, Cultured|Transcriptome|Cell Proliferation|Signal Transduction 18 MTCH1 32636717 Clin Proteomics 2020 PMC7331219 10.1186/s12014-020-09288-5 0 0 0 78 Humans|*Peptides|Spectrometry, Mass, Electrospray Ionization|Chromatography, Liquid|Tandem Mass Spectrometry|Proteomics|Proteins|*Plasma|Amino Acid Sequence|*Sepsis 18 NEXN 32635769 Circ Heart Fail 2020 10.1161/CIRCHEARTFAILURE.120.006935 2 0 0 128 Humans|Adult|*Myocytes, Cardiac|Sarcolemma|Microfilament Proteins|Intercellular Junctions 40 NEXN 32615730 Endocrinol Metab (Seoul) 2020 10.3803/EnM.2020.35.2.456 0 0 0 128 Mice|Animals|*Osteogenesis|*Osteocytes|*Cell Differentiation|Osteoblasts|*Skull|Osteoclasts|Bone Resorption|Periosteum|Hindlimb Suspension|Bone Diseases, Metabolic|*Transcriptome Profiling|Sequence Analysis, RNA 40 NEXN 32227427 NMR Biomed 2020 10.1002/nbm.4300 0 0 0 128 Animals|Mice|Reproducibility of Results|*Feasibility Studies|*Imaging, Magnetic Resonance|Stroke Volume|Magnetic Resonance Imaging, Cine|Cardiac-Gated Imaging Techniques|Image Interpretation, Computer-Assisted|Cardiac Imaging Techniques|Ventricular Function, Left|Electrocardiography|Heart|*Radiography|Heart Rate 40 NEXN 32041989 Sci Rep 2020 PMC7010767 10.1038/s41598-020-58984-7 0 0 0 128 Humans|*Cardiomyopathy, Dilated|Prospective Studies|*Genotype-Phenotype Correlations|Connectin|Heterozygote|Phenotype|Pedigree|Cardiomyopathies|Sequencing, Next-Generation|Mutation|Cardiac Transplantation|Proportional Hazards Models 40 NEXN 31983221 Circulation 2020 PMC7004454 10.1161/CIRCULATIONAHA.119.037661 2 0 0 128 Humans|*Cardiomyopathy, Dilated|Exome|Genetic Testing|Genetic Predisposition to Disease|Heterogeneities, Genetic 40 NLRP9 32542766 FEBS Lett. 2020 10.1002/1873-3468.13866 0 0 0 79 Humans|*Inflammasomes|*Pyrin Domain|NLR Family, Pyrin Domain-Containing 3 Protein|Caspase 1|Pyrin|CARD Signaling Adaptor Proteins|Cytoskeletal Proteins|Protein Binding|Amino Acid Sequence|Carrier Proteins|Crystallography, X-Ray|Immunity, Innate 18 NLRP9 32542665 FEBS Lett. 2020 10.1002/1873-3468.13865 0 0 0 79 Humans|*Inflammasomes|*Pyrin Domain|NLR Family, Pyrin Domain-Containing 3 Protein|Carrier Proteins|CARD Signaling Adaptor Proteins|Protein Structure, Tertiary|Cytoskeletal Proteins|Protein Binding|Protein Multimerization|Amino Acid Sequence|Models, Molecular 18 NLRP9 32413845 Reproduction 2020 10.1530/REP-19-0516 0 0 0 79 Male|Female|Mice|Animals|*Embryonic Development|Preimplantation Embryos|Oocytes|Fertilized Eggs|Reproduction|Mammals 18 NLRP9 32399794 J. Assist. Reprod. Genet. 2020 PMC7311623 10.1007/s10815-020-01767-w 0 0 0 79 Female|Mice|Humans|Animals|*Preimplantation Embryo Development|Blastocyst|Oocytes|Ovarian Follicle 18 NLRP9 32386845 Mol. Aspects Med. 2020 10.1016/j.mam.2020.100859 0 0 0 79 Humans|*Inflammasomes|NLR Family, Pyrin Domain-Containing 3 Protein|Inflammation|Signal Transduction|NF-kappa B|Immunity, Innate|Mitogen-Activated Protein Kinases|Intestine|Intestinal Mucosa|Carrier Proteins|Myeloid Cells 18 NLRP9 32326631 Animals (Basel) 2020 PMC7222816 10.3390/ani10040689 0 0 0 79 Female|Pregnancy|Sheep|Animals|Litter Size|Genotype|Breeding|Polymorphism, Single-Stranded Conformational|Gene Frequency|*Mutations|Reproduction|Polymorphism, Single Nucleotide|Polymerase Chain Reaction 18 NSUN5 32435407 ACS Med Chem Lett 2020 PMC7236227 10.1021/acsmedchemlett.9b00679 0 0 0 43 Humans|Melanoma|Proto-Oncogene Proteins B-raf|Protein Kinase Inhibitors|Drug Resistance, Neoplasm|Cell Line, Tumor|MAP Kinase Signaling System|Mutation|pyrimidine|*Pyrimidines 18 NSUN5 32316617 Int J Mol Sci 2020 PMC7215676 10.3390/ijms21082816 0 0 0 43 Methylation|RNA|RNA, Messenger|Adenosine|Methyltransferases|Epigenesis, Genetic 18 PHF3 32343561 J. Am. Chem. Soc. 2020 10.1021/jacs.0c01574 0 0 0 73 *Porphyrins|Metalloporphyrins|Fullerenes|Electron Transport|*Fluorination|Aluminum|Recombination, Genetic 19 RASEF 32256934 Int J Clin Exp Pathol 2020 PMC7090249 0 0 0 44 *Prognosis|*Colorectal Cancer|*Colonic Neoplasms|ras Guanine Nucleotide Exchange Factors 18 RIPPLY2 32278351 BMC Musculoskelet Disord 2020 PMC7149842 10.1186/s12891-020-03229-x 0 0 0 35 *Klippel-Feil Syndrome|*Multifactorial Inheritance|Vertebrae|*Mutations|Pedigree 31 RIPPLY2 32212228 Am. J. Med. Genet. A 2020 10.1002/ajmg.a.61549 0 0 0 35 Humans|Klippel-Feil Syndrome|Spine|Jarcho-Levin syndrome|Abnormalities, Multiple|Radiography|Hernia, Diaphragmatic|Homozygote|*Neck|*Musculoskeletal Abnormalities|Spinal Diseases|Sequencing, Whole Exome|Mutation|Exon|Magnetic Resonance Imaging|Phenotype 31 RNASEH2C 32062129 Stem Cell Res 2020 10.1016/j.scr.2019.101697 0 0 0 27 Humans|*SAM Domain and HD Domain-Containing Protein 1|*Sterile Alpha Motif|Nervous System Malformations|Autoimmune Diseases of the Nervous System|three prime repair exonuclease 1|Exodeoxyribonucleases|*Aicardi Syndrome|Phosphoproteins|HTT protein, human|*Huntingtin Protein|Ribonuclease H|Phenotype|Interferon-Induced Helicase, IFIH1|*Synapsins|Adenosine Deaminase|*Genomics|Mutation|Monomeric GTP-Binding Proteins 28 SIL1 32502168 PLoS ONE 2020 PMC7274380 10.1371/journal.pone.0234132 0 0 0 203 Humans|Mice|Animals|*Insulin|*Mice, Inbred C57BL|*Insulin, Regular, Human|Insulin Secretion|Blood Glucose|Oral Glucose Tolerance Test|*Phenotype|Quantitative Trait Loci|Diabetes Mellitus, Type 2|Glucose|Obesity|Impaired Glucose Tolerance|Crosses, Genetic|Genotype|Body Weight|Genetic Linkage Analysis|TCERG1 protein, human|Transcriptional Elongation Factors 101 SIL1 31900673 Clin Oral Investig 2020 10.1007/s00784-019-03136-z 0 0 0 203 *Ceramic|Resin Cements|Acid Etching, Dental|Composite Resins|Tooth Preparation, Prosthodontic|Cementation|Materials Testing|Incisor|Surface Properties 101 SLC35F2 32641414 Cancer Res. 2020 10.1158/0008-5472.CAN-20-0104 0 0 0 61 Humans|Adult|Female|*Forkhead Box Protein L2|Granulosa Cell Tumor|*Mutation|Forkhead Transcription Factors|Ovarian Neoplasms|Point Mutation|Missense Mutation|Gene Expression Regulation|Promoter Regions, Genetic|Cell Line, Tumor|*Specificity|FOXL2 protein, human|SLC35F2 protein, human|Membrane Transport Proteins 18 SLC35F2 32629102 Fish Shellfish Immunol. 2020 10.1016/j.fsi.2020.06.050 0 0 0 61 Animals|*Isavirus|*Orthomyxoviruses|Orthomyxoviridae Infections|*Transcriptome|Fish Diseases|Interferon Type I|Innate Immune Responses|Salmo salar|Cell Line|Aquiculture|Downregulation|Up-Regulation|Gene Expression Profiling|South Australia 18 SLC35F2 32357518 Cancers (Basel) 2020 PMC7281096 10.3390/cancers12051080 0 0 0 61 YM 155|*Naphthoquinones|BIRC5 protein, human|Survivin|*Imidazoles|Inhibitor of Apoptosis Proteins|Neuroblastoma|Cell Line, Tumor|Drug Resistance, Neoplasm|Xenograft Model Antitumor Assays|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B|*B-Lymphocytes|Cell Survival|*Biomarkers 18 SLFN5 32488136 Br. J. Cancer 2020 10.1038/s41416-020-0873-z 0 0 0 77 Humans|Zinc Finger E-box-Binding Homeobox 1|Epithelial-Mesenchymal Transition|Zinc Finger E-box Binding Homeobox 2|Homeodomain Proteins|Gene Expression Regulation, Neoplastic|Transcription Factors|MicroRNAs|Cell Movement|Cell Line, Tumor|Cell Proliferation|Lung Neoplasms|*Sarcoma|ZEB1 protein, human 18 SNORD48 32030798 Andrologia 2020 10.1111/and.13539 0 0 0 0 Humans|Male|*Asthenozoospermia|Sperm Motility|*Spermatozoa|Infertility, Male|MicroRNAs|Real-Time Polymerase Chain Reaction|Case-Control Studies 18 SPATA7 31908400 Mol. Vis. 2020 PMC6925664 0 0 0 20 Leber Congenital Amaurosis|*Mutations|Retinitis Pigmentosa|Pedigree|Eye Proteins|Phenotype|Retina|Genotype|DNA-Binding Proteins 33 SPG11 32641631 Rinsho Shinkeigaku 2020 10.5692/clinicalneurol.60.cn-001419 0 0 0 77 Male|Female|Humans|Aged|Middle Aged|Spastic paraplegia 11, autosomal recessive|Spastic Paraplegias, Hereditary|Spastic paraplegia 15, autosomal recessive|Proteins|Mutations|Genes, Recessive|Corpus Callosum|Retinal Degeneration|Carrier Proteins|Heterozygote|Pedigree|Exon|Magnetic Resonance Imaging|Genetic Heterogeneity|Mutation, Frame Shift|Paraplegia|SPG11 protein, human|spastizin protein, human 177 SPG11 32619247 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.07.002 0 0 0 77 Humans|*Spastic Paraplegia, Hereditary|*Pedigree|Genes, Recessive|Phenotype|Proteins|Mutation|Asian Continental Ancestry Group 177 SPG11 32593884 J. Neurol. Sci. 2020 10.1016/j.jns.2020.116982 0 0 0 77 Humans|Spastic paraplegia 11, autosomal recessive|*Spastic Paraplegia, Hereditary|Cross-Sectional Studies|Case-Control Studies|Mutations|Magnetic Resonance Imaging|Phenotypes|*Hypothalamus|Proteins|Pedigree|*Obesity|SPG11 protein, human 177 SPG11 32383541 Mol Genet Genomic Med 2020 PMC7336765 10.1002/mgg3.1240 1 0 0 77 Humans|Spastic paraplegia 11, autosomal recessive|*Autosomal Recessive Hereditary Spastic Paraplegia|*Amyotrophic Lateral Sclerosis|*Mutations|*Phenotype|DNA Mutational Analysis|Genes, Recessive|Pedigree|Corpus Callosum|Proteins|Asian Continental Ancestry Group|SPG11 protein, human 177 SPG11 32355960 Brain 2020 10.1093/brain/awaa099 0 0 0 77 Humans|Spastic paraplegia 11, autosomal recessive|*Spastic Paraplegia, Hereditary|Genes, Recessive|Proteins|Pedigree|Phenotypes|Mutation|Corpus Callosum|Lysosomes|SPG11 protein, human 177 SPG11 32242913 Neurol. Neurochir. Pol. 2020 10.5603/PJNNS.a2020.0026 0 0 0 77 Humans|*Spastic Paraplegia, Hereditary|Turkey|Spastin|DNA Mutational Analysis|Adenosine Triphosphatases|Genetic Predisposition to Disease|Pedigree|GTP-Binding Proteins|Asian Continental Ancestry Group|Mutation|Membrane Proteins 177 SPG11 32214227 Eur. J. Hum. Genet. 2020 10.1038/s41431-020-0609-9 0 0 0 77 Humans|*Arabs|*Exome|*Whole Exome Sequencing|Homozygote|DNA Mutational Analysis|Mutations|Pedigree|Polymorphism, Single Nucleotide|Inbreeding|Genetic Association Studies|*Disorders, Neurological|Cohort Studies|Israel|APTX protein, human|DNA-Binding Proteins|Nuclear Proteins|CNTNAP1 protein, human|Cell Adhesion Molecules, Neuronal 177 SPG11 32166880 Eur. J. Neurol. 2020 10.1111/ene.14213 0 0 0 77 Humans|*Amyotrophic Lateral Sclerosis|RNA-Binding Protein FUS|Superoxide Dismutase-1|Genetic Association Studies|Mutations|Phenotype|Superoxide Dismutase|Genetic Predisposition to Disease|DNA-Binding Proteins|*Chromosome Structures|China 177 SPG11 32040826 J. Mol. Neurosci. 2020 10.1007/s12031-020-01501-2 0 0 0 77 Humans|Female|Animals|Spastic paraplegia 11, autosomal recessive|*Spastic Paraplegia, Hereditary|*Lynx|Iran|*Mutation|*Spastic Paraplegia|Exon|Pedigree|Corpus Callosum|Proteins|Asian Continental Ancestry Group|Magnetic Resonance Imaging|SPG11 protein, human 177 SPG11 32007496 Neurosci. Lett. 2020 10.1016/j.neulet.2020.134800 0 0 0 77 Humans|Spastic paraplegia 11, autosomal recessive|*Spastic Paraplegia, Hereditary|*Roma|Genes, Recessive|Heterozygote|Homozygote|Phenotype|Pedigree|Mutation|*Ethnic Groups|Proteins|Asian Continental Ancestry Group|Haplotype|SPG11 protein, human|FARS2 protein, human|Phenylalanine-tRNA Ligase|Mitochondrial Proteins 177 SPG11 31969655 Sci Rep 2020 PMC6976666 10.1038/s41598-020-57929-4 0 0 0 77 Humans|Child|*Intellectual Disability|DNA Copy Number Variations|Prospective Studies|*Phenotypes|*Genotype|Genotype-Phenotype Correlations|Pedigree|Genetic Linkage|Mutations|Neurodevelopmental Disorders|Sequencing, Whole Genome|Epilepsy|Polymorphism, Single Nucleotide|SPG11 protein, human|Proteins 177 SPG11 31939580 Arq Neuropsiquiatr 2020 10.1590/0004-282X20190180 0 0 0 77 *Spastic Paraplegia, Hereditary|*Deglutition Disorders|*Prevalence|Spastin|Phenotype|Mutation|Adenosine Triphosphatases 177 SPG11 31900114 BMC Neurol 2020 PMC6941247 10.1186/s12883-019-1593-y 0 0 0 77 Humans|Spastic paraplegia 11, autosomal recessive|*Spastic Paraplegia, Hereditary|*Mutations|*Chinese|DNA Mutational Analysis|Genes, Recessive|Pedigree|Proteins|Corpus Callosum|SPG11 protein, human 177 TESMIN 32661276 Nat Plants 2020 10.1038/s41477-020-0710-7 0 0 0 39 *DNA Methylation|Arabidopsis|Arabidopsis Proteins|DNA (Cytosine-5-)-Methyltransferases|DNA-Cytosine Methylases|Gene Expression Regulation, Plant|Epigenesis, Genetic|DNA|TSO1 protein, Arabidopsis 18 TESMIN 31916570 Biol. Reprod. 2020 PMC7124961 10.1093/biolre/ioaa002 0 0 0 39 Male|Female|Mice|Animals|tesmin|*Metallothionein|*Spermatogenesis|Testis|Spermatogonia|Spermatocyte 18 wdr81 32410094 Cerebellum 2020 10.1007/s12311-020-01135-5 0 0 0 101 Animals|Pontocerebellar Hypoplasia|Odonata|*Cerebellar Diseases|Olivopontocerebellar Atrophies|Cerebellum|Pons|Imaging, Magnetic Resonance|Optic Atrophy|Mutation 18 ATXN8OS 31554751 Intern. Med. 2019 PMC7008061 10.2169/internalmedicine.2905-19 0 0 0 39 Humans|*Twins, Monozygotic|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Pedigree|Nerve Tissue Proteins|Phenotype|Imaging, Magnetic Resonance|RNA, Long Noncoding 70 ATXN8OS 31471687 J. Neurol. 2019 10.1007/s00415-019-09519-2 1 0 0 39 Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Pedigree|Nerve Tissue Proteins|RNA, Long Noncoding|Mainland China 70 ATXN8OS 31173245 Mol Med Rep 2019 PMC6625414 10.3892/mmr.2019.10367 0 0 0 39 Humans|Female|*RNA, Long Noncoding|MCF-7 Cells|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Movement|Apoptosis|Upregulation|*Biological Processes|MIRN204 microRNA, human 70 CAMK1G 31715283 Prog. Neuropsychopharmacol. Biol. Psychiatry 2019 10.1016/j.pnpbp.2019.109815 0 1 0 35 Humans|Adolescent|Adult|*Gene Modules|*Schizophrenia|Gene Expression Profiling|Transcriptome|Repurposing, Drug|Protein-Serine-Threonine Kinases|Brain|*Early Intervention, Educational|Spain 18 CDHR5 31660331 Open Forum Infect Dis 2019 PMC6778425 10.1093/ofid/ofz337 0 0 0 51 Adult|Humans|*Sarcoma, Kaposi|Iran|Herpesvirus 8, Human|*Genotype|*Sequencing, Whole Genome|Genetic Predisposition to Disease|Pedigree|Genetic Linkage|Case-Control Studies|Genome|Skin Neoplasms 19 CDHR5 31482521 Ir J Med Sci 2019 10.1007/s11845-019-02092-7 0 1 0 51 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Immunohistochemistry|Hep G2 Cells|Cell Proliferation|Kaplan-Meier Estimate|Down-Regulation|Cell Line, Tumor 19 CHURC1 30956117 Mol Metab 2019 PMC6531807 10.1016/j.molmet.2019.03.004 4 0 0 49 Humans|*Quantitative Trait Loci|*Diabetes Mellitus, Type 2|*Laser Capture Microdissection|Genome-Wide Association Study|*Pancreatic Islets|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Transcriptome Analysis|Transcriptome 18 CHURC1 30903564 Int. J. Hematol. 2019 10.1007/s12185-019-02630-0 0 0 0 49 Humans|Female|Infant|*DNA Copy Number Variations|Comparative Genomic Hybridization|*Spherocytosis, Hereditary|*Sequencing, Next-Generation|Spectrin|Ankyrins|Pedigree|Osmotic Fragility|Mutation|Exon|Asian Continental Ancestry Group 18 CNTNAP5 30883267 Pharmacogenomics 2019 PMC6563266 10.2217/pgs-2018-0163 3 0 0 24 *Genome-Wide Association Study|*Antipsychotic Agents|Schizophrenia|Pharmacogenomic Variants|Pharmacogenetics|Polymorphism, Single Nucleotide 18 CNTNAP5 30722798 Psychol Med 2019 10.1017/S0033291719000072 0 0 0 24 *Depressive Disorder, Major|*Whole Exome Sequencing|*Magnetic Resonance Imaging|Gray Matter|Brain|*Psychotherapy 18 CPXM2 31651348 Diagn Pathol 2019 PMC6813969 10.1186/s13000-019-0887-0 0 1 0 18 18 CPXM2 31364750 Oncol. Rep. 2019 PMC6718098 10.3892/or.2019.7254 2 1 0 18 18 CPXM2 30968809 J Dev Orig Health Dis 2019 PMC6786904 10.1017/S2040174418000545 1 0 0 18 18 CPXM2 30791149 Eur. J. Oral Sci. 2019 10.1111/eos.12607 0 0 0 18 18 DIRAS1 31197034 J. Biol. Chem. 2019 PMC6682747 10.1074/jbc.RA119.007438 1 1 0 155 *Small GTPases|Guanine Nucleotide Exchange Factors|Guanosine Diphosphate|*Molecular Chaperones|Guanosine Triphosphate|Protein Prenylation|Amino Acid Sequence|Protein Binding|rhoA GTP-Binding Protein|ras GTPases|Signal Transduction|Plasma Membrane 18 DNAH1 31765523 Pediatr. Pulmonol. 2019 10.1002/ppul.24583 0 0 0 6 Humans|Turkey|*Phenotype|Kartagener Syndrome|*Genotype|Homozygote|Genetic Testing|Cilia|Mutation|Cytoskeletal Proteins 38 DNAH1 31628824 Basic Clin. Pharmacol. Toxicol. 2019 10.1111/bcpt.13342 0 0 0 6 Male|Animals|Rats|*Alcoholism|*Rats, Sprague-Dawley|*Hippocampus|Alcohol Drinking|*Gene Expression Profiling|Ethanol|*Microarray Analysis|Impairments, Cognitive|Oxidative Stress|Republic of Korea 38 DNAH1 31507630 Front Genet 2019 PMC6713718 10.3389/fgene.2019.00749 0 0 0 6 Humans|*Kartagener Syndrome|*Mutations|Axonemal Dyneins|Cilia|Heterozygote|Sequencing, Whole Exome|Genetic Heterogeneity|Heterotaxy Syndrome|Chinese 38 DNAH1 30944005 J Transl Med 2019 PMC6448266 10.1186/s12967-019-1867-6 1 0 0 6 Humans|*Stomach Neoplasms|*Adenocarcinoma|Antineoplastic Combined Chemotherapy Protocols|Neoplasm Staging|Disease-Free Survival|Mutation|Biomarkers, Tumor|Kaplan-Meier Estimate 38 DNAH1 30929735 Am. J. Hum. Genet. 2019 PMC6451729 10.1016/j.ajhg.2019.02.020 9 0 0 6 Male|Humans|Mice|Animals|Sperm Tail|Infertility, Male|*Alleles|Spermatozoa|Sequencing, Whole Exome|Homozygote|*Mutations|Flagella|Testis|Spermatogenesis|Cytoskeletal Proteins|Cohort Studies|DNAH1 protein, human|Dyneins 38 DNAH1 30904354 Reprod. Biomed. Online 2019 10.1016/j.rbmo.2018.12.037 3 0 0 6 Humans|Male|*Sperm Flagellum|*Infertility, Male|*Mutations|Spermatozoa|Microtubule Proteins|Whole Exome Sequencing|*Multiple Abnormalities|Cytoskeletal Proteins|Flagella|AKAP4 protein, human|A Kinase Anchor Proteins|DNAH1 protein, human|Dyneins 38 DNAH1 30867909 Basic Clin Androl 2019 PMC6398242 10.1186/s12610-019-0083-9 2 5 0 6 Humans|Male|*Sperm Tail|*Infertility, Male|Sperm|Asthenozoospermia|Flagella|Whole Exome Sequencing|Cytoskeletal Proteins|Mutations|Cohort Studies 38 DNAH1 30734403 Mol. Reprod. Dev. 2019 10.1002/mrd.23120 0 0 0 6 Humans|Mice|Male|Animals|Sperm Motility|*Alleles|*Sperm|Infertility, Male|Dyneins|Fertilization|Oocytes|Fertilization in Vitro|Zona Pellucida|Homozygote|Fertility|Mutation|DNAH1 protein, human 38 DNAH1 30686508 Am. J. Hum. Genet. 2019 PMC6372258 10.1016/j.ajhg.2018.12.013 9 0 0 6 Male|Humans|Mice|Animals|*Sperm Tail|*Teratozoospermia, Astheno|Infertility, Male|Sperm|*Alleles|Axonemes|*Mutations|Sequencing, Whole Exome|Homozygote|Flagella|Phenotype|Cytoskeletal Proteins|Multiple Abnormalities|DNAH1 protein, human|Dyneins|SPAG6 protein, mouse|Microtubule Proteins|SPEF2 protein, mouse 38 FRAS1 31833050 Genes Genomics 2019 10.1007/s13258-019-00891-x 1 0 0 93 Swine|Animals|Breeding|Chromosome Mapping|Sequence Analysis, DNA|Selection, Genetic|Quantitative Trait Loci|Sus scrofa|Haplotypes|Polymorphism, Single Nucleotide 106 FRAS1 31678370 Exp. Hematol. 2019 PMC6910948 10.1016/j.exphem.2019.10.001 1 3 0 93 Humans|*Thrombocythemia, Essential|*Primary Myelofibrosis|*Bone Marrow|Polycythemia Vera|Janus Kinase 2|Megakaryocytes|Myeloproliferative Disorders|Mutation|Fibrosis|Proteins|Case-Control Studies 106 FRAS1 31597194 Int. J. Cancer 2019 10.1002/ijc.32705 0 1 0 93 Humans|Mice|Animals|*Stomach Neoplasms|Phosphatidylinositol 3-Kinases|Neoplasm Recurrence, Local|*Liver Neoplasms|Extracellular Matrix Proteins|Extracellular Matrix|Phenotype|Mutation|Disease Models, Animal|Gene Expression|Fras1 protein, mouse 106 FRAS1 31554749 Exp. Anim. 2019 PMC7004800 10.1538/expanim.19-0088 0 0 0 93 Mice|Animals|Fraser Syndrome|*Mutation|Extracellular Matrix Proteins|Homozygotes|Kidneys|Fras1 protein, mouse 106 FRAS1 31447598 Clin Med Insights Oncol 2019 PMC6689917 10.1177/1179554919868482 1 0 0 93 Humans|*Triple Negative Breast Neoplasms|*Mutation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 106 FRAS1 31419934 BMC Genomics 2019 PMC6697907 10.1186/s12864-019-6010-9 1 0 0 93 Swine|Animals|*Transcriptome|Animal Feed|Animal Nutritional Physiological Phenomena|Breeding|Eating|Phenotype|*Machine Learning|Gene Expression Profiling|*Muscle|*Dietary Supplements|Computational Biology 106 FRAS1 31316547 Front Genet 2019 PMC6610066 10.3389/fgene.2019.00590 4 0 0 93 Swine|Animals|*Phosphorus|Genome-Wide Association Study|*Alkaline Phosphatase|Calcium, Dietary|Quantitative Trait Loci|Phenotype|Minerals|Genomics|Polymorphism, Single Nucleotide|Homeostasis 106 FRAS1 30935378 BMC Genomics 2019 PMC6444876 10.1186/s12864-019-5638-9 0 0 0 93 Cattle|Female|Animals|Genome-Wide Association Study|*Fertility|Quantitative Trait Loci|Linkage Disequilibrium|Phenotype|Breeding|*Genetic Testing|Milk|Polymorphism, Single Nucleotide 106 FRAS1 30802441 Exp. Eye Res. 2019 10.1016/j.exer.2019.02.013 1 0 0 93 Humans|Mice|Animals|Fraser Syndrome|*Mutations|Extracellular Matrix Proteins|*Organogenesis|Eyelids|Missense Mutation|Disease Models, Animal|FREM2 protein, human|Fras1 protein, mouse 106 FRAS1 30772743 J Affect Disord 2019 10.1016/j.jad.2019.02.028 2 1 0 93 Humans|*Bipolar Disorder|*Whole Exome Sequencing|*Imaging, Magnetic Resonance|White Matter|Diffusion Tensor Imaging|Brain|*Biomarkers|Case-Control Studies 106 GALK2 31148553 Int J Oral Sci 2019 PMC6544625 10.1038/s41368-019-0051-4 0 1 0 63 Child|Humans|Adolescent|*Streptococcus mutans|*Genome-Wide Association Study|Dental Caries|DMF Index|*Primary Dentition|Saliva|Colony Count, Microbial|Tooth Loss|Appalachia|Iowa|GALK2 protein, human|Galactokinase 18 GATOR 31650955 Elife 2019 PMC6834368 10.7554/eLife.42149 0 1 0 0 Animals|Drosophila Proteins|Drosophila melanogaster|Meiosis|Oocytes|DNA Breaks, Double-Stranded|Cell Cycle Proteins|DNA Repair|TORC1 55 GATOR 31440961 Int J Comput Assist Radiol Surg 2019 10.1007/s11548-019-02056-3 0 0 0 0 Humans|*Operating Rooms|Computer Communication Networks|Physicians|Vendors 55 GATOR 31281815 Front Cell Dev Biol 2019 PMC6595708 10.3389/fcell.2019.00113 9 50 0 0 Glycogen Synthase Kinase 3|*Lysosome|*Signal Transduction|mTORC1|Autophagy|TOR Serine-Threonine Kinases|Phagocytosis|Endocytosis|ATPase, Vacuolar|*Metabolic Networks and Pathways|Cell Proliferation 55 GATOR 31247628 Dement Geriatr Cogn Disord 2019 10.1159/000497803 0 0 0 0 Assisted Living Facilities|Independent Living|Self-Help Devices|Delivery of Health Care 55 GATOR 30911571 Ann Clin Transl Neurol 2019 PMC6414475 10.1002/acn3.722 0 1 0 0 *Focal Epilepsies|Mechanistic Target of Rapamycin Complex 1|TOR Serine-Threonine Kinases|GTPase-Activating Proteins|Pedigree|Mutation|Tumor Suppressor Proteins|Signal Transduction|Genetic Predisposition to Disease|Repressor Proteins 55 GATOR 30859526 J Spec Oper Med 2019 0 0 0 0 Retrospective Studies|War-Related Injuries|Military Medicine|Resuscitations|Transportation of Patients|Emergency Medical Services|Africa 55 GDF6 31868592 Elife 2019 PMC6968919 10.7554/eLife.50047 1 0 0 120 Animals|*Zebrafish|*Melanocyte|Zebrafish Proteins|Embryo, Nonmammalian|*Signal Transduction|Neural Crest|Microphthalmia-Associated Transcription Factor|Gene Expression Regulation, Developmental|Cell Differentiation|*Ligands|Melanoma 114 GDF6 31739923 Neurosurg. Clin. N. Am. 2019 PMC6899505 10.1016/j.nec.2019.08.015 0 0 0 120 Animals|Intervertebral Disk|Intervertebral Disc Degeneration|Tissue Engineering|Regeneration|*Gene Therapy|Stem Cell Transplantation|*Growth Factors|*B-Lymphocytes|*Mammals 114 GDF6 31637734 J. Cell. Physiol. 2019 10.1002/jcp.29355 0 5 0 120 *Aspirin|*Tendon|*Cell Differentiation|*Stem Cells|*Signal Transduction|*Tendinopathy|*Wound Healing|Tendon Injuries|GDF11 protein, human|Bone Morphogenetic Proteins|Growth Differentiation Factors|Transforming Growth Factor beta1|Cells, Cultured 114 GDF6 31095236 Rev Chil Pediatr 2019 10.32641/rchped.v90i2.779 0 0 0 120 Klippel Feil syndrome dominant type|*Klippel-Feil Syndrome|Cervical Vertebrae|Radiography|Mutations 114 GDF6 31066515 J Tissue Eng Regen Med 2019 PMC6771973 10.1002/term.2882 3 0 0 120 Humans|*Nucleus Pulposus|GDF6 protein, human|*Growth Differentiation Factor 6|*Adipocytes|Intervertebral Disk Degeneration|Cell Differentiation|Intervertebral Disc|Stem Cells|Hydrogel|A73025|Glycosaminoglycans|Adipose Tissue|Aggrecan|*Cell-Derived Microparticles|Regeneration 114 GDF6 31002939 Osteoarthr. Cartil. 2019 10.1016/j.joca.2019.04.002 5 0 0 120 *Intervertebral Disc Degeneration|Mesenchymal Stem Cell|Intervertebral Disc|Mesenchymal Stem Cell Transplantation|*Stem Cell|Cells, Cultured 114 GDF6 30733656 Mol Syndromol 2019 PMC6362854 10.1159/000492418 0 1 0 120 Synostosis|Foot Deformities, Congenital|Stapes|Hand Deformities, Congenital|Phenotype|Carpal Bones|Tarsal Bones|Pedigree|Carrier Proteins|Mutation|Amino Acid Sequence 114 GDF6 30716505 Biochim Biophys Acta Proteins Proteom 2019 10.1016/j.bbapap.2019.01.013 2 0 0 120 Humans|*Mesenchymal Stem Cells|*Bone Marrow|Bone Marrow Cells|Proteome|Cell Proliferation|Cytokines|Cells, Cultured|Hematopoiesis|*Bone and Bones 114 gpr19 31622017 IUBMB Life 2019 10.1002/iub.2187 1 2 0 4 Rats|Mice|Animals|*RNA, Long Noncoding|*Mice, Inbred C57BL|Myocardial Reperfusion Injury|*Myocardial Infarction|*Oxidative Stress|Cardiomyocytes|Apoptosis|MicroRNAs|Myocardium|Gene Expression Regulation|Signal Transduction|Glucose|*Cell Death|GPR19 protein, rat|Nerve Tissue Proteins|Receptors, Neurotransmitter|Receptors, G-Protein-Coupled 18 gpr19 31400396 Mol. Cell. Endocrinol. 2019 10.1016/j.mce.2019.110532 3 4 0 4 Mice|Humans|Rats|Animals|*3T3-L1 Cells|*Cell Differentiation|Adipocytes|Adipogenesis|Cell Proliferation|PPAR gamma|Adipose Tissue|Lipogenesis|Obesity|mRNA|Body Weight|Metabolic Syndrome|Enho protein, human|Blood Proteins|Peptides|GPR19 protein, rat|Nerve Tissue Proteins|Receptors, Neurotransmitter 18 hoxa13 31851934 Cell Rep 2019 PMC6956710 10.1016/j.celrep.2019.11.077 0 0 0 346 275 hoxa13 31745224 Sci Rep 2019 PMC6864077 10.1038/s41598-019-53370-4 1 0 0 346 275 hoxa13 31697875 Mol. Cells 2019 PMC6883981 10.14348/molcells.2019.0121 0 2 0 346 275 hoxa13 31445923 Dev. Biol. 2019 10.1016/j.ydbio.2019.08.014 0 0 0 346 275 hoxa13 31434870 Cell Death Dis 2019 PMC6704151 10.1038/s41419-019-1865-x 0 0 0 346 275 hoxa13 31328440 Mol Genet Genomic Med 2019 PMC6732273 10.1002/mgg3.870 1 3 0 346 275 hoxa13 31234415 Cells 2019 PMC6627321 10.3390/cells8060623 0 0 0 346 275 hoxa13 31165722 Cell Death Dis 2019 PMC6549185 10.1038/s41419-019-1631-0 0 1 0 346 275 JPH1 31748560 Sci Rep 2019 PMC6868129 10.1038/s41598-019-52841-y 0 0 0 121 Humans|Uveal melanoma|*Prospective Studies|Neoplasm Recurrence, Local|*Uveal Neoplasms|*Melanoma|*Liver Neoplasms|Prognosis|*Gene Expression|Gene Expression Regulation, Neoplastic|*Neoplasms, Glandular and Epithelial|Gene Expression Profiling|Real Time PCR|PTP4A3 protein, human|Neoplasm Proteins|Protein Tyrosine Phosphatases 18 JPH1 31337710 J. Biol. Chem. 2019 PMC6737222 10.1074/jbc.RA118.006772 1 1 0 121 junctophilin|Membrane Proteins|Sarcoplasmic Reticulum|Plasma Membranes|Ryanodine Receptor Calcium Release Channel|Endoplasmic Reticulum|Protein Domains|Palmitic Acid 18 JPH1 31315980 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6681751 10.1073/pnas.1820980116 0 0 0 121 junctophilin|*Membrane Proteins|*Skeletal Muscle Fibers|Sarcoplasmic Reticulum|Muscle Proteins|Skeletal Muscles|Sarcolemma|Muscle Contraction|Triad resin|*Acrylic Resins|Calcium|Protein Domains 18 JPH1 30804591 J Pak Med Assoc 2019 0 0 0 121 Humans|*Polymorphism, Single Nucleotide|Charcot-Marie-Tooth disease, Type 2K|*Charcot-Marie-Tooth Disease|Phenotype|Nerve Tissue Proteins|Mutation|Pedigree|Membrane Proteins|Modifier Gene|Genetic Susceptibility|Age of Onset|Severity of Illness Index 18 KLHL10 31479588 Andrology 2019 10.1111/andr.12704 1 0 0 45 Humans|Male|*Infertility, Male|Azoospermia|Whole Exome Sequencing|Spermatogenesis|Genetic Predisposition to Disease|Sequencing, Next-Generation|Mutation|Testis 18 KLHL10 31065688 J Mol Cell Biol 2019 PMC7052986 10.1093/jmcb/mjz035 1 1 0 45 Humans|Male|Mice|Animals|*Testis|*Aging, Premature|*Spermatogenesis|Transcription Factor IID|TATA-Binding Protein Associated Factors|Azoospermia|Transcription Factors|Spermatozoa|DNA-Binding Proteins|Transcription, Genetic|Fertility|BNC1 protein, human|Ybx2 protein, mouse|RNA-Binding Proteins|TAF7L protein, mouse|Odf1 protein, mouse|Heat-Shock Proteins|Bnc1 protein, mouse 18 KLHL10 30697164 Front Physiol 2019 PMC6341066 10.3389/fphys.2018.01920 0 0 0 45 18 KLHL10 30629479 OMICS 2019 10.1089/omi.2018.0155 0 1 0 45 Humans|Male|Mice|Animals|*Epididymis|*Proteomics|Sperm Maturation|Spermatogenesis|Testis|Spermatozoa|Infertility, Male|Fertility 18 KLHL40 31647849 PLoS ONE 2019 PMC6812755 10.1371/journal.pone.0223024 0 0 0 71 Humans|*Transcriptome|*Acute Exercise|*Muscle, Skeletal|Running|Blood Glucose|Insulin|Fatty Acids, Nonesterified|Human Growth Hormone|Lactic Acid 19 KLHL40 31360996 J. Neuropathol. Exp. Neurol. 2019 10.1093/jnen/nlz056 1 0 0 71 Humans|*Myopathies, Nemaline|*Ethnic Groups|*Hyponatremia|Muscle Proteins|Muscle, Skeletal|*Chinese|Mutation|Hongkong|KLHL40 protein, human 19 KLHL40 31228046 J. Muscle Res. Cell. Motil. 2019 PMC6726674 10.1007/s10974-019-09519-9 5 0 0 71 Adult|Humans|Animals|Child|*Myopathies, Nemaline|Activities of Daily Living|nebulin|Muscle Proteins|Muscle Weakness|Muscle, Skeletal|Actin|Sarcomeres|Phenotypes|Mutations|Hypotonia|Electron Microscopy|KLHL40 protein, human 19 KLHL40 30990797 JCI Insight 2019 PMC6542616 10.1172/jci.insight.125665 0 1 0 71 Humans|Mice|Animals|*Myopathies, Nemaline|*Cullin Proteins|Muscle Protein|ACTN4 protein, human|*Actinin|ACTN1 protein, human|Muscle Weakness|Muscle, Skeletal|Mice, Knockout|Myoblasts|E3 Ubiquitin Ligase|Disease Models, Animal|Mutations|KLHL40 protein, human 19 LACTB 30662658 Am J Transl Res 2019 PMC6325492 11 2 0 114 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|Neoplasm Recurrence, Local|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Movement|Cell Line, Tumor|Downregulation|*Neoplastic Processes|Disease Progression|mRNA|LACTB protein, human|beta-Lactamases|Membrane Proteins|Mitochondrial Proteins 18 LMLN 30984245 Front Genet 2019 PMC6448551 10.3389/fgene.2019.00274 3 0 0 98 Swine|Animals|*Homozygote|Inbreeding|Genome|Genotype|Phenotype|Genetics, Population|Breeding|SNPs|Genomics|Chromosomes|Reproduction|*Disclosure 18 MESP2 30980111 Cell. Mol. Life Sci. 2019 10.1007/s00018-019-03096-3 0 0 0 93 Humans|Amyotrophic Lateral Sclerosis|Huntington Disease|Alzheimer Disease|Parkinson Disease|Prion Diseases|MIRN92 microRNA, human|MicroRNAs|Mitochondria|Peptides|*Recognition, Psychology|Dystrophy, Myotonic|Amyloidosis|Amino Acid Sequence|PTCD3 protein, human|RNA-Binding Proteins|Arabidopsis Proteins|SYPL2 protein, human|Synaptophysin 95 MIR193A 31497188 Am J Transl Res 2019 PMC6731400 1 9 0 1 *Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Tumor Suppressor Protein p53|*Acetylation|A549 Cells|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|*Neovascularization, Pathologic|Down-Regulation|Cell Line, Tumor|*Neoplastic Processes 18 MIR193A 31116585 Am. J. Physiol., Cell Physiol. 2019 PMC6732421 10.1152/ajpcell.00538.2018 4 3 0 1 Humans|APOL1 protein, human|*Apolipoprotein L1|*Podocytes|*Autophagy|*Apolipoproteins B|Lysosome|HEK293 Cells|Genetic Variation|Phenotype|Genes, Regulator 18 MIR193A 30837512 Sci Rep 2019 PMC6401370 10.1038/s41598-019-39376-y 0 41 0 1 *Podocytes|APOL1 protein, human|*Apolipoprotein L1|*Actin Cytoskeleton|nephrin|Membrane Proteins|Phenotype|Downregulation|Cell Differentiation 18 MMRN2 31422156 Matrix Biol. 2019 10.1016/j.matbio.2019.08.002 1 2 0 55 multimerin|KDR protein, human|VEGFR-2|*Blood Proteins|Neovascularization, Pathologic|elastin microfibril interface located protein|Membrane Glycoproteins|cadherin 5|Cadherins|Antigens, CD|Signal Transduction|Cell Adhesion|Human Umbilical Vein Endothelial Cells|Intercellular Junctions|Phosphorylation|Antigens, Surface|Protein Binding|*Permeability 18 MMRN2 31263680 Front Oncol 2019 PMC6584847 10.3389/fonc.2019.00513 0 0 0 55 Humans|*Stomach Neoplasms|*Stomach|Neoplasm Grading|Microscopy, Confocal|*Endoscopy|*Neoplasms, Second Primary 18 NEXN 31830726 Atherosclerosis 2019 10.1016/j.atherosclerosis.2019.11.033 3 7 0 128 Humans|*Pyroptosis|*RNA, Long Noncoding|*Endothelial Cells|*Atorvastatin|NLR Family, Pyrin Domain-Containing 3 Protein|Caspase 1|Inflammasomes|Atherosclerosis|Interleukin-1beta|Signal Transduction|Programmed Cell Death 40 NEXN 31611379 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6825283 10.1073/pnas.1911429116 0 0 0 128 Humans|*Autistic Disorder|*Esophageal Achalasia|Autism Spectrum Disorder|Intellectual Disability|Forkhead Transcription Factors|Repressor Proteins|Language Disorders|Mutation 40 NEXN 31477192 Cardiol Young 2019 10.1017/S1047951119001860 0 0 0 128 Humans|NAV1.5 Voltage-Gated Sodium Channel|Arrythmia|Pedigree|Cardiomyopathy, Dilated|Electrocardiography|Sudden Cardiac Arrest|Genetic Predisposition to Disease|Mutation|Cardiomyopathy 40 NEXN 31392414 Int. J. Legal Med. 2019 10.1007/s00414-019-02127-9 0 0 0 128 *Autopsy|*Transcriptome|*Sudden Cardiac Death|*Whole Exome Sequencing|Genetic Testing|Mutations|High-Throughput Nucleotide Sequencing|*Heart|Forensic Pathology|Genetic Predisposition to Disease|Myocardium 40 NEXN 30982350 Circulation 2019 PMC6889818 10.1161/CIRCULATIONAHA.119.039751 3 2 0 128 Mice|Animals|Sarcoplasmic Reticulum|Sarcolemma|*Intercellular Junctions|Calcium Channels, L-Type|Myocytes, Cardiac|Cardiomyopathy, Dilated|Calcium Signaling|Heart Failure|Mice, Knockout|Microfilament Proteins|Mutations|Genetic Predisposition to Disease|*Cytoplasm 40 NEXN 30882937 J. Cell. Biochem. 2019 10.1002/jcb.28554 1 0 0 128 *RNA, Long Noncoding|*Brain Ischemia|*Stroke|Messenger RNA|Gene Regulatory Networks|RNA, Micro|Gene Expression Profiling|Transcriptome|Biomarkers 40 NSUN5 31722427 Nucleic Acids Res. 2019 PMC7145617 10.1093/nar/gkz1043 2 0 0 43 Humans|Mice|Animals|rRNA (adenosine-O-2'-)methyltransferase|*Methyltransferases|RNA, ribosomal, 25S|RNA, Ribosomal|*Protein Biosynthesis|Saccharomyces cerevisiae|Ribosome|Methylation|28S Ribosomal RNA 18 NSUN5 31462248 Mol Brain 2019 PMC6714381 10.1186/s13041-019-0496-6 1 0 0 43 Mice|Animals|Humans|*RNA|Neuroglia|Cerebral Cortex|Neurons|Mice, Knockout|Cell Polarity|Radial Glial Cells|Cell Movement|*Methyltransferases|cdc42 Protein|Nerve Tissue Proteins|Cell Differentiation|Progenitor Cells 18 NSUN5 31428936 Acta Neuropathol. 2019 PMC6851045 10.1007/s00401-019-02062-4 6 0 0 43 Humans|*RNA|*Glioma|*Methyltransferases|DNA Methylation|*Ribosomes|Epigenesis, Genetic|5 Methylcytosine|Genes, Tumor Suppressor|*Epigenetic|Protein Biosynthesis 18 NSUN5 31204697 J. Genet. 2019 0 0 0 43 Humans|*Williams Syndrome|Chromosome Deletion|In Situ Hybridization, Fluorescence|Phenotype|Microsatellite Repeats 18 NSUN5 31174389 Cells 2019 PMC6627898 10.3390/cells8060552 1 1 0 43 Mice|Animals|*Corpus Callosum|*RNA|Oligodendroglia|Myelin Sheath|Neural Stem Cells|Mice, Knockout|*Methyltransferases|Cell Differentiation|Cell Proliferation|Disease Models, Animal 18 PNPLA1 31833240 Mol Genet Genomic Med 2019 PMC7005637 10.1002/mgg3.1076 1 0 0 24 Humans|*Ichthyosis, Lamellar|Genes, Recessive|Pedigree|Mutations|Phenotype|Transglutaminases|Lipase|*Chinese|PNPLA1 protein, human 42 PNPLA1 31734953 Cell. Microbiol. 2019 10.1111/cmi.13146 0 0 0 24 Animals|*Plasmodium falciparum|*Parasites|*Phospholipase|*Plasmodium falciparum Malaria|Protozoan Proteins|Reproduction, Asexual 42 PNPLA1 31168818 Br. J. Dermatol. 2019 10.1111/bjd.18211 2 0 0 24 Humans|*Ichthyosis, Lamellar|Ichthyosiform Erythroderma, Congenital|*Genotype-Phenotype Correlation|Genes, Recessive|Genotype|Phenotype|Mutation|Arachidonate 12-Lipoxygenase|Transglutaminases|Lipoxygenase|*Cohort Studies 42 PNPLA1 31120544 Acta Derm. Venereol. 2019 10.2340/00015555-3227 2 0 0 24 Humans|*Founder Effect|*Ichthyosis, Lamellar|*Mutations|Genes, Recessive|Heterozygote|Codon, Nonsense|Pedigree|Mutation, Missense|Phenotype|Haplotype|Lipase|*Databases, Genetic|PNPLA1 protein, human 42 PNPLA1 30978464 J Proteomics 2019 10.1016/j.jprot.2019.04.007 1 0 0 24 Humans|*Proteomics|*Ichthyosis, Lamellar|Genes, Recessive|Ichthyosiform Erythroderma, Congenital|Ichthyosis|Phenotype|Mutations|Skin|Genotype|Pedigree|Epidermis|Transglutaminases|Gene Expression Profiling|Lipase|PNPLA1 protein, human|SDR9C7 protein, human|Oxidoreductases 42 PNPLA1 30655104 J. Dermatol. Sci. 2019 10.1016/j.jdermsci.2018.11.013 0 1 0 24 Humans|*Lipid Droplets|*Ichthyosis, Lamellar|*Mutations|Genes, Recessive|Pedigree|Epidermis|Skin|Lipase|*Fibroblasts|*Lipophagy|Cell Differentiation|PNPLA1 protein, human 42 RASEF 30941313 Front Oncol 2019 PMC6434718 10.3389/fonc.2019.00164 0 4 0 44 Humans|NCOA2 protein, human|*Nuclear Receptor Coactivator 2|*MAP Kinase Signaling System|Nuclear Receptor Coactivator 3|Cell Line, Tumor|G-T mismatch-binding protein|DNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation 18 RASEF 30888555 Mol. Biol. Rep. 2019 10.1007/s11033-019-04663-4 1 0 0 44 Humans|*Prognosis|Bayes Theorem|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Receptors, Estrogen|Gene Expression Profiling|Biomarkers, Tumor|Protein Interaction Maps|Computational Biology|mRNA|Transcriptome|Kaplan-Meier Estimate|CPEB2 protein, human|RNA-Binding Proteins|ANXA9 protein, human|Annexins 18 RASEF 30845941 Respir. Res. 2019 PMC6407244 10.1186/s12931-019-1014-1 0 44 0 44 *DNA Methylation|*Pulmonary Arterial Remodeling|Hypertension, Pulmonary|*Smoke|Pulmonary Artery|Myocytes, Smooth Muscle|Hypertrophy, Right Ventricular|*Tobacco|Muscle, Smooth, Vascular|Smoking|Cell Proliferation 18 RASEF 30814157 J. Cell Biol. 2019 PMC6504896 10.1083/jcb.201806097 3 4 0 44 *Dynein Activator Protein|*Dyneins|Microtubules|Microtubule-Associated Proteins|Cytoplasmic Dyneins|rab GTPases|Endocytosis|T Cells|*Calcium, Dietary|Cell Movement|Protein Binding|Protein Transport|Organelle 18 RIPPLY2 31250914 Int. J. Dev. Biol. 2019 PMC7032064 10.1387/ijdb.190006ed 0 0 0 35 Animals|*Xenopus laevis|Gastrula|Xenopus Proteins|Organizers, Embryonic|Blastula|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|*Transcriptome Analysis|Germ Layer|Transcriptome|Amino Acid Sequence|Regeneration 31 RNASEH2C 31715598 Cytogenet. Genome Res. 2019 10.1159/000504075 0 0 0 27 Humans|Female|*Calcinosis|*Basal Ganglia|*Calcification, Physiologic|Chromosome Deletion|Karyotyping|Phenotype|*Chromosome Structures|Translocation, Genetic|Intellectual Disability|Brain Diseases|SPTBN2 protein, human|Spectrin|B3GNT1 protein, human 28 RNASEH2C 31559893 J. Child Neurol. 2019 10.1177/0883073819870944 0 0 0 27 Autoimmune Diseases of the Nervous System|Nervous System Malformations|*Aicardi Syndrome|Ribonuclease H|Interferon-Induced Helicase, IFIH1|Exodeoxyribonucleases|Phosphoproteins|Mutation 28 RNASEH2C 31130681 J Clin Med 2019 PMC6572054 10.3390/jcm8050750 0 0 0 27 *Interferon|Italy|Nervous System Malformations|Autoimmune Diseases of the Nervous System|*Aicardi Syndrome|Ribonuclease H|SAM Domain and HD Domain-Containing Protein 1|Exodeoxyribonucleases|Adenosine Deaminase|*Antiviral Agents|Phenotype|Monomeric GTP-Binding Proteins|Phosphoproteins|Mutation 28 RNASEH2C 31125342 PLoS Genet. 2019 PMC6553800 10.1371/journal.pgen.1008020 1 0 0 27 Humans|Animals|Mice|Autoimmune Diseases of the Nervous System|Nervous System Malformations|Ribonuclease H|*Aicardi Syndrome|MB21D1 protein, human|Nucleotidyltransferases|Mutation|RNase 28 RNASEH2C 30952201 Pediatr. Dev. Pathol. 2019 10.1177/1093526619837797 0 2 0 27 Nervous System Malformations|Autoimmune Diseases of the Nervous System|*Nervous System Diseases|Interferon-Induced Helicase, IFIH1|*Neuropathology|Mutations|Brain Diseases|Atrophy 28 RNASEH2C 30692772 Ann Indian Acad Neurol 2019 PMC6327704 10.4103/aian.AIAN_12_18 1 2 0 27 Autoimmune Diseases of the Nervous System|Nervous System Malformations|*Aicardi Syndrome|Ribonuclease H|Adenosine Deaminase|Exodeoxyribonucleases|Mutations|Phenotype|*Brain Diseases|Phosphoproteins|Spinal Cord 28 RNASEH2C 30622304 Cell Death Differ. 2019 PMC6748076 10.1038/s41418-018-0255-8 3 4 0 27 Aged, 80 and over|Humans|*Up-Regulation|*Genomic Stability|Longevity|DNA Repair|DNA Damage|Cell Senescence|Aging|Comet Assay|*Transcriptional Activation|*Phenotype|Fibroblasts|*Anti-Inflammatory Agents|Inflammation|MicroRNAs|Signal Transduction|Immunity, Innate 28 SGCZ 31742804 J Gene Med 2019 10.1002/jgm.3146 0 0 0 21 Humans|*Whole Exome Sequencing|*Exome|*Cardiomyopathy, Hypertrophic|*Mutation|Pedigree|*Chinese|Myocardium|FHOD3 protein, human|Formins 19 SGCZ 31646556 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201910_19136 0 0 0 21 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Cystadenocarcinoma, Serous|*Prognosis|Neoplasms, Glandular and Epithelial|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Biomarkers, Tumor|Kaplan-Meier Estimate|Neoplasm Grading|Cell Transformation, Neoplastic|Gene Expression 19 SIL1 31834482 Plant Cell Rep. 2019 10.1007/s00299-019-02498-8 0 0 0 203 *Zea mays|*Retroelements|Allele|Genome, Plant|Seeds|*Dwarfism|Phenotype|*Spaceflight 101 SIL1 31791191 Sci Prog 2019 10.1177/0036850419891046 0 6 0 203 Humans|Female|*Apoptosis|*Cell Cycle|MCF-7 Cells|Cell Proliferation|Cell Migration|CCND1 protein, human|Cyclin D1|Cell Line, Tumor|RNA, Small Interfering|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|G1 Phase|Transfection|*Cell Division|Nucleotides|SIL1 protein, human 101 SIL1 31701543 Neuropathol. 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Physiol. 2019 10.1002/jcp.28906 1 0 0 61 *Proto-Oncogene Proteins B-raf|Papillary Thyroid Cancer|Thyroid Neoplasms|Carcinoma, Papillary|Mutation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor 18 SLC35F2 31157201 Front Chem 2019 PMC6532689 10.3389/fchem.2019.00298 0 0 0 61 Humans|*Pluripotent Stem Cells|YM 155|*Naphthoquinones|*Imidazoles|*Cell Death|*Structure-Activity Relationship|Human Embryonic Stem Cells|Cell Differentiation|*Antineoplastic Agents|Cell Survival|Cell Line, Tumor|Teratoma 18 SLFN5 31683647 Int J Mol Sci 2019 PMC6862440 10.3390/ijms20215437 0 1 0 77 Humans|Pancreatic Carcinoma|*Pancreatic Cancer|DNA Methylation|Promoter Regions, Genetic|Prognosis|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Biomarkers, Tumor|Kruppel-Like Transcription Factors|Adenocarcinoma|Cell Proliferation|Zinc Finger|ZNF154 protein, human 18 SLFN5 31472120 Eur. J. Pharmacol. 2019 10.1016/j.ejphar.2019.172630 1 3 0 77 Humans|*Epithelial-Mesenchymal Transition|*Cell Line, A549|*Cadherins|*Lung Cancer|Snail Family Transcription Factors|*Catenins|Transcription Factor|beta Catenin|Cell Movement|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Signal Transduction|Antigens, CD|Lung 18 SLFN5 31081970 J. Cell. Biochem. 2019 10.1002/jcb.28876 0 0 0 77 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Acute Lymphoblastic Leukemia|B-Lymphocytes|Sequencing, RNA|Transcriptomes|Gene Expression Profiling|Antigens, CD19|Gene Expression Regulation, Neoplastic|Base Sequence 18 SLFN5 30844429 Cell. Signal. 2019 10.1016/j.cellsig.2019.03.004 4 14 0 77 Humans|*Glycogen Synthase Kinase 3|*Proto-Oncogene Proteins c-akt|*Matrix Metalloproteinase 14|*MMP Inhibitors|*Cell Migration|beta Catenin|Signal Transduction|*Catenins|Phosphorylation|Cell Line, A549|Cell Proliferation|Cell Line, Tumor|Lung Cancer|Colorectal Cancer 18 SNORD48 31856234 PLoS ONE 2019 PMC6922460 10.1371/journal.pone.0226571 0 0 0 0 *Lab-On-A-Chip Devices|*miRNAs|Electrophoresis|Real-Time Polymerase Chain Reaction|Microfluidic|Oligonucleotide Array Sequence Analysis|Nucleic Acids|Equipment Design|Cancers 18 SNORD48 31788707 Int. J. Legal Med. 2019 10.1007/s00414-019-02210-1 0 0 0 0 Humans|*Paraffin Embedding|Tissue Fixation|Formaldehyde|*Noncoding RNA|Real-Time Polymerase Chain Reaction|Gene Expression Profiling|mRNA|RNA, Long Noncoding|Specimen Handling|Brain 18 SNORD48 31012127 Andrologia 2019 10.1111/and.13284 1 0 0 0 Humans|Male|*Asthenozoospermia|Sperm Motility|*Spermatozoa|Infertility, Male|Oligospermia|Semen|Fertility|MicroRNAs|Transcriptome|Real Time PCR 18 SPATA7 31695380 Neuropsychiatr Dis Treat 2019 PMC6707433 10.2147/NDT.S218773 0 0 0 20 Humans|*Heterozygote|Exome|Pedigree|Sequencing, Whole Exome|Genetic Predisposition to Disease|Genotype|Genetic Variation|Asian Continental Ancestry Group|Schizophrenia|Siblings|Case-Control Studies|Mutation|Sequence Analysis 33 SPATA7 31406157 Sci Rep 2019 PMC6691113 10.1038/s41598-019-48186-1 0 0 0 20 Humans|*Carotid Intima-Media Thickness|*Genetic Linkage|*Atherosclerosis|Quantitative Trait Locus|Carotid Artery Diseases|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Pedigree|*Hispanic Americans|Phenotype|Sequence Analysis, DNA|Exons|PRIMA1 protein, human|Membrane Proteins|Nerve Tissue Proteins|SPATA7 protein, human 33 SPATA7 30647131 J. 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Neurol. 2019 10.1007/s00415-019-09633-1 2 0 0 77 Humans|*Spastic Paraplegia, Hereditary|*Genotype-Phenotype Associations|Spastin|Phenotypes|Genotypes|Pedigree|Adenosine Triphosphatases|Membrane Proteins|Mutation 177 SPG11 31637311 Commun Biol 2019 PMC6797781 10.1038/s42003-019-0615-z 3 3 0 77 *Calcium|*Protein Transport|Lysosomes|*Cholesterol|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Autophagy|Signal Transduction|*Cell Movement|Homeostasis 177 SPG11 31475037 Front Genet 2019 PMC6707335 10.3389/fgene.2019.00732 2 0 0 77 Humans|*Amyotrophic Lateral Sclerosis|Neurodegenerative Diseases|Hungary|C9orf72 Protein|*Genetic Testing|Superoxide Dismutase-1|Genetic Association Studies|Genetic Predisposition to Disease|*Cohort Studies|Genetic Variation|High-Throughput Nucleotide Sequencing|Mutation 177 SPG11 31396143 Front Neurol 2019 PMC6667642 10.3389/fneur.2019.00758 4 0 0 77 Neurodegenerative Diseases|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|Dermatitis, Seborrheic|Malassezia|Parkinson Disease|Neurons, Dopamine|Skin 177 SPG11 31385551 Int. 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Rep. 2019 10.3892/or.2019.7145 2 0 0 39 Humans|Male|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|tesmin|*Metallothionein|Immunohistochemistry|Prognosis|Carcinoma, Squamous Cell|Adenocarcinomas|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cytoplasm|Biomarkers, Tumor|Cell Nuclei|Lung|Cell Proliferation 18 ADTRP 30571485 J Am Heart Assoc 2018 PMC6404433 10.1161/JAHA.118.010690 2 36 0 78 Animals|Mice|lipoprotein-associated coagulation inhibitor|Endothelial Cells|Zebrafish|Zebrafish Proteins|*Lipoproteins|Neovascularization, Physiologic|cadherin 5|Cadherins|Wnt Signaling Pathway|*Androgens|Antigens, CD|Membrane Proteins 18 ARL5B 30545942 J. Biol. Chem. 2018 PMC6364769 10.1074/jbc.RA118.005222 7 4 0 224 Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Amyloid beta-Protein Precursor|trans-Golgi Network|Golgi Apparatus|Alzheimer Disease|Endosomes|Protein Transport|Plasma Membrane 18 ARL5B 30200873 BMC Genomics 2018 PMC6131827 10.1186/s12864-018-5052-8 5 11 0 224 Animals|Rats|*Long Non-Coding RNA|*mRNA|*RNA, Circular|*Ethylene Glycol|Gene Expression Profiling|Gene Ontology|Gene Regulatory Networks|MicroRNAs|Transcriptome|Computational Biology|*Calculi, Kidney 18 ATXN8OS 30109267 Neurol Genet 2018 PMC6089696 10.1212/NXG.0000000000000252 2 2 0 39 Humans|*Amyotrophic Lateral Sclerosis|Japan|Trinucleotide Repeat Expansion|Spinocerebellar Degenerations|Nerve Tissue Proteins|RNA, Long Noncoding 70 ATXN8OS 29916049 Cerebellum 2018 10.1007/s12311-018-0955-0 2 0 0 39 Humans|Aged|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|*Phenotype|Pedigree|Nerve Tissue Proteins|RNA, Long Noncoding|Mutations|Age-at-Onset|Ataxia 70 CDHR5 30296522 Hum. Pathol. 2018 10.1016/j.humpath.2018.09.019 0 2 0 51 Humans|*Colorectal Neoplasms, Hereditary Nonpolyposis|Colorectal Cancer|beta Catenin|Cadherins|Immunohistochemistry|Signal Transduction|Prognosis|Downregulation 19 CDHR5 29794245 Cancer Prev Res (Phila) 2018 10.1158/1940-6207.CAPR-17-0382 1 6 0 51 Humans|*Mesalamine|*Colon Cancer|*Colon|beta Catenin|*Catenins|Wnt Signaling Pathway|Cadherins|Downregulation|Gene Expression Regulation, Neoplastic|HCT116 Cells|Cell Line, Tumor|Cell Transformation, Neoplastic 19 CHURC1 30096133 PLoS Genet. 2018 PMC6105030 10.1371/journal.pgen.1007586 10 0 0 49 Humans|*Phenotype|Traits, Complex|African Americans|Hispanic|Genome-Wide Association Study|European Continental Ancestry Group|Quantitative Trait Loci|Ethnic Groups|Allele Frequency|Polymorphism, Single Nucleotide|Genotype|Chromosome Mapping|Gene Expression Regulation|*Gene Expression|Cohort Studies|TACSTD2 protein, human|Antigens, Neoplasm|Cell Adhesion Molecules 18 CHURC1 29440776 Eur. J. Hum. 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Physiol. 2018 10.1002/jcp.27376 1 0 0 155 *Genes, Tumor Suppressor|rho GTP-Binding Proteins|Gene Expression Regulation, Neoplastic|Tumor Suppressor Proteins|ras Proteins|Signal Transduction|Cell Line, Tumor|Cell Proliferation|Apoptosis|Cell Cycle 18 DIRAS1 30161023 Mol Ther Nucleic Acids 2018 PMC6118159 10.1016/j.omtn.2018.07.019 0 17 0 155 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|Cell Proliferation|Downregulation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Movement|Genes, Tumor Suppressor|Apoptosis|Promoter Regions, Genetic|Disease Progression|Transfection|DIRAS1 protein, human|GTP Phosphohydrolases|Tumor Suppressor Proteins 18 DIRAS1 29936662 J. Mol. Neurosci. 2018 10.1007/s12031-018-1102-6 2 0 0 155 Humans|*Parkinson Disease|Protein Interaction Maps|Gene Regulatory Networks|Oligonucleotide Array Sequence Analysis|miRNA|Gene Expression Profiling|*Biomarkers|Transcription Factors|*Disease Progression|Gene Expression|DIRAS1 protein, human|GTP Phosphohydrolases|Tumor Suppressor Proteins 18 DIRAS1 29556894 In Vitro Cell. Dev. Biol. Anim. 2018 10.1007/s11626-018-0239-5 2 4 0 155 *Carcinoma, Renal Cell|*Butyric Acid|*Autophagy|Kidney Neoplasms|*Cell Lineage|Cell Line, Tumor|*Cell Death|Histone Deacetylase Inhibitor|*Kidney|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Cycle Arrest|Tumor Suppressor Proteins|*Epithelial Cells|Genes, Tumor Suppressor 18 DIRAS1 29368982 Autophagy 2018 PMC5959337 10.1080/15548627.2018.1427022 5 8 0 155 Humans|Female|Mice|Animals|*ras-Related GTPases|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Autophagy|rho GTP-Binding Proteins|Cell Line, Tumor|Downregulation|MAP Kinase Signaling System|*Ovary|*Autophagic Cell Death|Cell Movement|DIRAS3 protein, human|DIRAS1 protein, human|GTP Phosphohydrolases|Tumor Suppressor Proteins 18 DNAH1 30544445 Medicine (Baltimore) 2018 PMC6310528 10.1097/MD.0000000000013493 2 0 0 6 Humans|Male|*Retrospective Studies|*Infertility, Male|Azoospermia, Nonobstructive|Azoospermia|Asthenozoospermia|Oligospermia|Exons|Chinese|Spermatozoa|Mutation|Polymorphism, Single Nucleotide|Exome|Case-Control Studies|DNAH1 protein, human|Dyneins 38 DNAH1 30415212 J. 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Genet. 2018 10.1136/jmedgenet-2018-105486 6 0 0 6 Humans|Male|Sperm Motility|*Homozygote|Infertility, Male|Sperm Tail|Spermatozoa|Spermatozoa, Abnormal|Flagella|Whole Exome Sequencing|Cytoskeletal Proteins|Mutation 38 DNAH1 32212452 Zhonghua Nan Ke Xue 2018 0 0 0 6 Humans|Male|*Teratozoospermia|Infertility, Male|Sperm Head|Aurora Kinase C|Spermatozoa|Membrane Proteins|Mutation|SUN5 protein, human|Proteins|DPY19L2 protein, human|DNAH1 protein, human|Dyneins|SPATA6 protein, human|Cytoskeletal Proteins 38 GALK2 30289335 Autophagy 2018 PMC6333447 10.1080/15548627.2018.1517855 3 0 0 63 Humans|Phosphatidylinositol 3-Kinases|Autophagy|Signal Transduction|TOR Serine-Threonine Kinases|IKBKE protein, human|I-kappa B Kinase 18 GATOR 30473811 R Soc Open Sci 2018 PMC6227984 10.1098/rsos.180418 0 0 0 0 *Sewage|*Alkali|*Biodegradation, Environmental|Crude Oil|*Oils|Soil Pollutants|Soil Microbiology 55 GATOR 30073236 Faraday Discuss. 2018 10.1039/c8fd00067k 0 0 0 0 *Molecular Structure|Crystallography, X-Ray|Molecular Conformation|Models, Molecular|Quantum Theory|Thermodynamics|Computer Simulation|Algorithms|*Heterocyclic Compounds|*Biological Evolution 55 GATOR 29769712 Nature 2018 10.1038/s41586-018-0114-2 0 0 0 0 *Signal Transduction|Actin|*Political Systems|Mechanistic Target of Rapamycin Complex 1 55 GATOR 29625022 Am. 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Genet. 2018 PMC5985289 10.1016/j.ajhg.2018.02.016 1 0 0 0 Humans|Retrospective Studies|Prospective Studies|*Phenotype|*Genetic Testing|Pedigree|Quantitative Trait Loci|Genetic Association Studies|Models, Genetic|Genome-Wide Association Study|SNPs|Framingham Heart Study|Trait, Complex|Software|Computer Simulation 55 GATOR 29481740 J Chem Theory Comput 2018 10.1021/acs.jctc.7b01152 4 0 0 0 *Molecular Structure|Molecular Conformation|Models, Molecular|Thermodynamics|Crystallography, X-Ray|Quantum Theory|Computer Simulation|Algorithms|*Heterocyclic Compounds 55 GDF6 30123278 Case Rep Med 2018 PMC6079567 10.1155/2018/3871425 0 0 0 120 Humans|Female|Child|*Syndrome|Leri pleonosteosis|Hand Deformities, Congenital|Ossification, Heterotopic|Facies|Joint Diseases|Phenotype|*Brain 114 GDF6 29859287 Gene 2018 PMC6269229 10.1016/j.gene.2018.05.110 1 3 0 120 Rats|Animals|*Myocytes, Cardiac|CTSG protein, human|*Cathepsin G|*Animals, Newborn|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Signal Transduction|Gene Expression Profiling|Gene Expression Regulation|Gene Expression Profiles|Apoptosis|Cells, Cultured|Fosl2 protein, rat|Fos-Related Antigen-2 114 GDF6 29461140 Ophthalmic Genet. 2018 10.1080/13816810.2018.1436184 1 0 0 120 Humans|*Anophthalmos|*Microphthalmos|*Eye|Coloboma|Homeodomain Proteins|Eye Proteins|Mutation|Transcription Factors|SOXB1 Transcription Factors|Phenotype|Genes, Developmental|India 114 gpr19 30466987 Phytomedicine 2018 10.1016/j.phymed.2018.09.204 6 5 0 4 *Systems Biology|Rhodiola|Eleutherococcus|Schisandra|Plant Extracts|Gene Expression Profiling|Plant Roots|Neuroglia|Stress, Physiological|Signal Transduction|Longevity|Cell Line|*Brain 18 gpr19 30339292 Exp. Dermatol. 2018 10.1111/exd.13809 2 0 0 4 Humans|*Protons|G2A receptor|*G-Protein-Coupled Receptors|GPR68 protein, human|*Skin Cancers|Cell Cycle Proteins|Hydrogen-Ion Concentration|Tumor Microenvironment 18 gpr19 29909017 Redox Biol 2018 PMC6008287 10.1016/j.redox.2018.06.003 8 26 0 4 *Signal Transduction|*MAP Kinase Signaling System|GPRC5C protein, human|Receptors, G-Protein-Coupled|Phosphorylation|Cardiomyocytes|Mitochondria, Heart|MAPK3 protein, human|p44 MAPK|Glucose|Myocardium|Cell Line|Pyruvate|*Oxidoreductases 18 JPH1 30556166 J. Cell. Biochem. 2018 10.1002/jcb.28151 1 0 0 121 Humans|Uveal melanoma|*Prognosis|*DNA Methylation|Likelihood Functions|*Uveal Neoplasms|*Melanoma|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Survival Analysis|Proportional Hazards Model|*Gene Expression|*Neoplasms, Second Primary 18 KLHL10 30544396 Medicine (Baltimore) 2018 PMC6310515 10.1097/MD.0000000000013338 0 1 0 45 Male|Humans|*Asthenozoospermia|*Sperm|*Infertility, Male|Sperm Motility|Testis|*In Silico|Protein Interaction Maps|Biomarkers|Case-Control Studies 18 KLHL10 29731491 J. Reprod. Dev. 2018 PMC6105735 10.1262/jrd.2018-024 0 4 0 45 Male|Female|Mice|Animals|*Oocytes|Oogenesis|*Spermatogenesis|Ovaries|Germ Cells|Embryonic Development|Gene Expression Regulation, Developmental|Transcription Factors|Mice, Transgenic|mRNA|Cell Differentiation|Cell Nucleus|Tnp2 protein, mouse|Nuclear Proteins 18 LACTB 30216112 FASEB J. 2018 10.1096/fj.201701394RRR 5 4 0 114 Humans|Male|Mice|Animals|*Muscle Development|*miRNA|RNA, Long Noncoding|Myoblast|Cell Differentiation|Cell Proliferation|Muscle Fibers, Skeletal|Muscle, Skeletal|Cell Line|LACTB protein, human|beta-Lactamases|Membrane Proteins|Mitochondrial Proteins 18 LACTB 29899406 Oncogene 2018 10.1038/s41388-018-0352-7 6 7 0 114 Humans|Mice|Animals|TP53 protein, human|*Tumor Suppressor Protein p53|*Colorectal Cancer|*Ubiquitination|*Genes, Tumor Suppressor|*Disease Progression|Cell Proliferation|HCT116 Cells|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Movement|Mice, Nude|*Colonic Neoplasms|Epithelial-Mesenchymal Transition|Downregulation|Epigenesis, Genetic|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2 18 LACTB 29873754 J. 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Sci. 2018 PMC6095408 10.1093/jas/sky225 0 0 0 114 Humans|Swine|Animals|*Haplotypes|*Information Theory|Pigs, Domestic|Breeding|Genetic Variation|DNA, Mitochondrial|Genome|Phylogeny|*Asian|*Biological Evolution|Asia|Europe|Sequence Analysis, DNA|Genomics|Polymorphism, Single Nucleotide|LACTB protein, human|beta-Lactamases|Membrane Proteins 18 LACTB 29790671 Cancer Med 2018 PMC6051141 10.1002/cam4.1576 17 16 0 114 Humans|Female|Mice|Animals|*Up-Regulation|*Prognosis|*Disease Progression|Gene Expression Regulation, Neoplastic|MicroRNAs|*Downregulation|Genes, Tumor Suppressor|Cell Movement|Cell Proliferation|Cell Line, Tumor|*Transcriptional Activation|*Neoplasms, Second Primary|LACTB protein, human|beta-Lactamases|Membrane Proteins|Mitochondrial Proteins 18 LMLN 29714477 Inorg Chem 2018 PMC6016852 10.1021/acs.inorgchem.8b00120 1 0 0 98 *Protons|*Water|Gadolinium|Contrast Media|*Magnetic|Lanthanoid Series Elements|Magnetic Resonance Imaging|Magnetic Resonance Spectroscopy|*Transition Elements|Thermodynamics|*Physical Phenomena|Magnetic Phenomena 18 MESP2 30531807 J. Hum. Genet. 2018 10.1038/s10038-018-0548-2 0 0 0 93 Humans|Jarcho-Levin syndrome|*Hernia, Diaphragmatic|*Abnormalities, Multiple|MFNG protein, human|Intracellular Signaling Peptides and Proteins|Vertebrae|Membrane Proteins|Phenotype|Mutations|Ribs|T-Box Domain Proteins|Basic Helix-Loop-Helix Transcription Factors|Glycosyltransferases|Mutation, Missense|Hexosyltransferases|LFNG protein, human 95 MESP2 29681102 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.38668 0 6 0 93 Humans|Mice|Male|Animals|Jarcho-Levin syndrome|Hernia, Diaphragmatic|Abnormalities, Multiple|Spine|Dysostoses|*Homozygote|Ribs|Phenotype|Scoliosis|Radiography|Mutations|*Musculoskeletal Abnormalities|*Thoracic Diseases|Mice, Knockout|Lfng protein, mouse|Glycosyltransferases 95 MESP2 29459493 J. Med. Genet. 2018 10.1136/jmedgenet-2017-104939 0 1 0 93 Humans|*Retrospective Studies|*Vertebrae|Jarcho-Levin syndrome|Abnormalities, Multiple|Hernia, Diaphragmatic|Phenotype|Mutations|Pedigree|Basic Helix-Loop-Helix Transcription Factors|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Glycosyltransferases|Cohort Studies 95 MIR193A 30246800 Front Physiol 2018 PMC6113669 10.3389/fphys.2018.01136 3 1 0 1 *Biomarkers|*Exercise|Circulating MicroRNA|MicroRNAs|Real-Time Polymerase Chain Reaction 18 MIR193A 30201495 Am. J. Pathol. 2018 PMC6222279 10.1016/j.ajpath.2018.07.025 5 3 0 1 Mice|Animals|Humans|APOL1 protein, human|*Apolipoprotein L1|Podocyte|Kidney Glomerulus|*Transitional Epithelial Cell|Glomerulosclerosis, Focal Segmental|AIDS-Associated Nephropathy|Mice, Transgenic|VDR protein, human|Vitamin D Receptor|Phenotype|SYNPO protein, human|Microfilament Proteins|mRNA 18 MIR193A 30165047 Gastroenterology 2018 PMC6279541 10.1053/j.gastro.2018.08.032 16 4 0 1 Humans|Mice|Animals|Carcinoma, Hepatocellular|Liver Neoplasms|*MicroRNAs|*Carcinogenesis|Gene Expression Regulation, Neoplastic|Cell Proliferation|mRNA|Hep G2 Cells|Cell Movement|Signal Transduction|Cell Line, Tumor|Xenograft Model Antitumor Assays|Down-Regulation 18 MIR193A 30111726 Behav Sci (Basel) 2018 PMC6115946 10.3390/bs8080075 3 6 0 1 18 MIR193A 29357419 Am. J. Physiol. Renal Physiol. 2018 PMC6031922 10.1152/ajprenal.00541.2017 9 10 0 1 *Podocytes|APOL1 protein, human|*Apolipoprotein L1|MicroRNAs|EZH2 protein, human|Enhancer of Zeste Homolog 2|Wilms Tumor 1|Cell Differentiation|Downregulation|WT1 Proteins|Apoptosis|Signal Transduction|Upregulation|MEN1 protein, human|Proto-Oncogene Proteins|Kidney Neoplasms|Glucose 18 MMRN2 30419062 PLoS ONE 2018 PMC6231670 10.1371/journal.pone.0207204 3 1 0 55 Humans|*Lung Adenocarcinoma|Lung Cancer|Prognosis|*Mutations|Kaplan-Meier Analysis|Disease-Free Survival|Biomarkers, Tumor|*Machine Learning|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Gene Expression Profiling|Transcriptome|Survival Rate|Small Cell Lung Carcinoma|Cohort Studies|SETX protein, human|RNA Helicases 18 MMRN2 29763414 J. Clin. Invest. 2018 PMC6063507 10.1172/JCI97459 15 27 0 55 Mice|Animals|FN1 protein, human|*Fibronectins|*Neovascularization, Pathologic|Receptors, Complement|Cell Adhesion|Membrane Glycoproteins|Cell Movement|Human Umbilical Vein Endothelial Cells|Antigens, Surface|Filopodia|Cell Line, Tumor|Extracellular Matrix|Signal Transduction|Integrins 18 MTCH1 30128175 PeerJ 2018 PMC6097490 10.7717/peerj.5207 2 0 0 78 *Squamous Cell Carcinoma of Head and Neck|*Gene Expression|Quantitative Real Time PCR|Genes, Essential|Reference Standards|Gene Expression Profiling|Algorithms|*Biochemical Phenomena|Head and Neck Neoplasms 18 MTCH1 29974842 Cell. Mol. Biol. (Noisy-le-grand) 2018 0 0 0 78 Humans|*Reactive Oxygen Species|*Head and Neck Cancer|*Signal Transduction|Superoxide Dismutase|NAD(P)H Dehydrogenase (Quinone)|Apoptosis 18 NEXN 30589415 J. Clin. Invest. 2018 PMC6391138 10.1172/JCI98230 9 8 0 128 Mice|Humans|Animals|*RNA, Long Noncoding|*Atherosclerosis|Mice, ApoE Knockout|Plaques, Atherosclerotic|Coronary Artery Disease|Macrophage|Human Umbilical Vein Endothelial Cells|Gene Expression Regulation|THP-1 Cells|Signal Transduction|Downregulation|Monocytes|Cytokines|*Microfilament Proteins|BAZ1A protein, human|Transcription Factors 40 NEXN 30415094 Forensic Sci. Int. 2018 10.1016/j.forsciint.2018.09.034 3 0 0 128 Humans|Middle Aged|*Massively Parallel Sequencing|*Genetic Testing|Sudden Cardiac Death|*Autopsy|Channelopathies|Cardiomyopathies|Arrythmia|Sequence Analysis, DNA|*Databases, Genetic|Forensic Genetics|Genetic Counseling|Heart Disorders|Mutation|Phenotype 40 NEXN 30177952 Front Genet 2018 PMC6109778 10.3389/fgene.2018.00330 1 2 0 128 Sheep|Animals|*Rumen|*Methane|*Transcriptome|Ruminants|*Phenotypes|*Cell Junction|*Muscle|*Muscle Cell|*Lipids 40 NEXN 30158653 Sci Rep 2018 PMC6115340 10.1038/s41598-018-31328-2 1 23 0 128 myocardin|*Actins|*Polymerization|*Trans-Activators|*Nuclear Proteins|Smooth Muscle Cells|*Muscle, Smooth|Transcription Factors|Gene Expression Regulation|Microfilament Proteins|Promoter Regions, Genetic|Actin Cytoskeleton|Cell Differentiation|Membrane Proteins|latrunculin B|Bridged Bicyclo Compounds, Heterocyclic|Thiazolidines 40 NEXN 29367538 J Cardiovasc Dev Dis 2018 PMC5715703 10.3390/jcdd4020006 0 3 0 128 Humans|Animals|Mice|*Trastuzumab|*Cardiomyopathy, Dilated|Stroke Volume|Ventricular Function, Left|ERBB2 protein, human|Receptor, ErbB-2|*Heart|Single Nucleotide Polymorphisms|Genetic Association Studies|Allele Frequency|Doxorubicin|Genetic Predisposition to Disease|Genetic Testing|Phenotypes|*Rare Diseases|Cardiomyopathy|Antineoplastic Agents 40 NLRP9 30217166 J Neuroinflammation 2018 PMC6138928 10.1186/s12974-018-1307-1 4 0 0 79 Humans|*Multiple Sclerosis|*Exome|*Whole Exome Sequencing|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|*Disease Progression|Genotype 18 NLRP9 29670507 Front Neurosci 2018 PMC5893779 10.3389/fnins.2018.00209 3 2 0 79 Alzheimer disease type 2|*Alzheimer Disease|Genetic Association Studies|Genetic Predisposition to Disease|Genome-Wide Association Study|Exome|Polymorphism, Single Nucleotide|Case-Control Studies|Phenotype|Cohort Studies 18 NLRP9 29655793 Biochem. Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.04.079 5 7 0 79 Mice|Animals|*Acute Lung Injury|*Inflammation|*Oxidative Stress|*Apoptosis|Lipopolysaccharides|NF-kappa B|Mice, Inbred C57BL|Reactive Oxygen Species|Cytokines|Signal Transduction|Sepsis|Carrier Proteins|Disease Models, Animal 18 NSUN5 30485550 Glia 2018 10.1002/glia.23565 0 1 0 43 Mice|Animals|*Oligodendrocyte Precursor Cells|*RNA|NR2A NMDA receptor|Receptors, N-Methyl-D-Aspartate|Long-Term Potentiation|glutamate receptor ionotropic, AMPA 2|Receptors, AMPA|*Cognition Disorders|Mice, Knockout|Hippocampus|NMDA|Maze Learning|Neurons|*Cognitive Dysfunction|Cytosine 5-methyltransferase|*DNA-Cytosine Methylases|Neurogenesis|Synaptic Transmission 18 NSUN5 30256975 Nucleic Acids Res. 2018 PMC6265444 10.1093/nar/gky861 14 1 0 43 *G-Quadruplexes|Neurodegenerative Diseases|5' Untranslated Region|mRNA|Protein Biosynthesis|Transcriptome|Gene Expression Regulation|Proteomics 18 PHF3 30054919 Clin. Genet. 2018 10.1111/cge.13426 1 0 0 73 Humans|*Retinal Dystrophies|*Mutations|Homozygote|DNA Mutational Analysis|Pedigree|Phenotype|Genetic Heterogeneity|Sequencing, Whole Exome|Sequencing, Next-Generation|Eye Proteins|Introns 19 PNPLA1 30546811 Inflamm Regen 2018 PMC6284315 10.1186/s41232-018-0089-2 0 1 0 24 *Phospholipase B|Phospholipases A2, Secretory|Lipids|Lipid Metabolism|Eicosanoids|Skin 42 PNPLA1 30527376 J. Dermatol. Sci. 2018 10.1016/j.jdermsci.2018.11.005 9 1 0 24 Mice|Animals|Chanarin-Dorfman Syndrome|*Ichthyosiform Erythroderma, Congenital|*Lipid Metabolism, Inborn Errors|*Muscular Diseases|*Ichthyosis, Lamellar|1-Acylglycerol-3-Phosphate O-Acyltransferase|*Ichthyosis|Triglycerides|Mutations|Permeability|*Catalysis|Abhd5 protein, mouse|PNPLA1 protein, mouse|Lipase 42 PNPLA1 30361410 J. Lipid Res. 2018 PMC6277169 10.1194/jlr.M089771 11 3 0 24 Humans|Epidermis|Ichthyosis, Lamellar|Ichthyosis|Skin|Ceramides|Lipase|Permeability|*Central Nervous System Stimulants|ABHD5 protein, human|1-Acylglycerol-3-Phosphate O-Acyltransferase|PNPLA1 protein, human 42 PNPLA1 30290227 Biochim Biophys Acta Mol Cell Biol Lipids 2018 10.1016/j.bbalip.2018.09.010 8 0 0 24 Humans|Epidermis|Skin|Ceramides|Lipase|Permeability|PNPLA1 protein, human 42 PNPLA1 30011118 Hum. Mutat. 2018 10.1002/humu.23594 3 0 0 24 Humans|*Ichthyosis, Lamellar|Ichthyosiform Erythroderma, Congenital|*Mutation|Genes, Recessive|Pedigree|Phenotype|Genetic Testing|Skin|Cytochrome P-450 Enzyme System|Cohort Studies|ABCA12 protein, human|ATP-Binding Cassette Transporters|ichthyin protein, human|Receptors, Cell Surface|PNPLA1 protein, human|Lipase|SDR9C7 protein, human|Oxidoreductases 42 PNPLA1 29786154 Vet. Dermatol. 2018 10.1111/vde.12654 1 0 0 24 Animals|Dogs|*Prospective Studies|*Pilot Projects|*Ichthyosis, Lamellar|*Administration, Topical|Genes, Recessive|Skin|Epidermis|Pedigree|Dog Diseases|Mutation|Lipase 42 PNPLA1 29738490 Vet Sci 2018 PMC6024370 10.3390/vetsci5020048 0 0 0 24 Dogs|Animals|*Prevalence|Pedigree|Dog Diseases|Lipase 42 RASEF 30546460 Oncol Lett 2018 PMC6256290 10.3892/ol.2018.9542 0 0 0 44 Humans|Female|Receptor, ErbB-2|Receptors, Estrogen|Receptors, Progesterone|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic 18 RASEF 31949824 Int J Clin Exp Pathol 2018 PMC6962987 0 0 0 44 Humans|*Colorectal Cancers|Instability, Microsatellite|Mismatch Repair|*Prognosis|MutS Homolog 2 Protein|MutL Protein Homolog 1|Germ-Line Mutation|Biomarkers, Tumor|DNA Repair|Nuclear Proteins|DNA-Binding Proteins|Adaptor Proteins, Signal Transducing|*Colonic Neoplasms 18 RASEF 29578129 Chin. Med. J. 2018 PMC5887744 10.4103/0366-6999.228229 1 14 0 44 Uveal melanoma|*DNA Methylation|*B-DNA|*Uveal Neoplasms|*Melanoma|Epigenesis, Genetic|Gene Silencing|Promoter Regions, Genetic|DNA, Neoplasm|Gene Expression Regulation, Neoplastic 18 RIPPLY2 30531807 J. Hum. Genet. 2018 10.1038/s10038-018-0548-2 0 0 0 35 Humans|Jarcho-Levin syndrome|*Hernia, Diaphragmatic|*Abnormalities, Multiple|MFNG protein, human|Intracellular Signaling Peptides and Proteins|Vertebrae|Membrane Proteins|Phenotype|Mutations|Ribs|T-Box Domain Proteins|Basic Helix-Loop-Helix Transcription Factors|Glycosyltransferases|Mutation, Missense|Hexosyltransferases|LFNG protein, human 31 RIPPLY2 30420309 J Emerg Med 2018 10.1016/j.jemermed.2018.09.044 0 0 0 35 Out-of-Hospital Cardiac Arrest|Cardiopulmonary Resuscitation|Emergency Medical Services|Jarcho-Levin syndrome|Hernia, Diaphragmatic|Abnormalities, Multiple|Vertebrae 31 RIPPLY2 29895619 J. Biol. Chem. 2018 PMC6078462 10.1074/jbc.RA118.003728 3 1 0 35 Animals|*Mesoderm|*Transcription Factors|Somites|Basic Helix-Loop-Helix Transcription Factors|Receptors, Notch|Gene Expression Regulation, Developmental|Repressor Proteins|Binding Sites|Signal Transduction|Base Sequence|Embryogenesis 31 RIPPLY2 29879477 Mech. Dev. 2018 10.1016/j.mod.2018.06.001 0 7 0 35 Animals|*Zebrafish|Somites|*Mesoderm|Zebrafish Proteins|Body Patterning|T-Box Domain Proteins|Gene Expression Regulation, Developmental|*Gene Expression|Basic Helix-Loop-Helix Transcription Factors|Transcription Factor|Repressor Proteins|Nuclear Proteins 31 RIPPLY2 29761784 Elife 2018 PMC5953544 10.7554/eLife.33068 2 21 0 35 Mice|Animals|*Proteasome Endopeptidase Complex|Somites|*Embryonic Development|Mesoderm|Body Patterning|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Gene Expression Regulation, Developmental|T-Box Domain Proteins|Repressor Proteins 31 RIPPLY2 29681102 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.38668 0 6 0 35 Humans|Mice|Male|Animals|Jarcho-Levin syndrome|Hernia, Diaphragmatic|Abnormalities, Multiple|Spine|Dysostoses|*Homozygote|Ribs|Phenotype|Scoliosis|Radiography|Mutations|*Musculoskeletal Abnormalities|*Thoracic Diseases|Mice, Knockout|Lfng protein, mouse|Glycosyltransferases 31 RNASEH2C 29740948 Brain Pathol. 2018 10.1111/bpa.12600 2 0 0 27 *Astrocytes|Nervous System Malformations|Autoimmune Diseases of the Nervous System|SAM Domain and HD Domain-Containing Protein 1|three prime repair exonuclease 1|Exodeoxyribonucleases|*Aicardi Syndrome|Ribonuclease H|Phosphoproteins|Adenosine Deaminase|Mutations|Monomeric GTP-Binding Proteins|Interferon-alpha|Epilepsy|Cytokines 28 SGCZ 29545918 Oncotarget 2018 PMC5837756 10.18632/oncotarget.24336 3 5 0 21 Humans|Female|*DNA Copy Number Variations|Comparative Genomic Hybridization|*Databases, Genetic 19 SIL1 30468864 Neurobiol. Dis. 2018 10.1016/j.nbd.2018.11.019 0 1 0 203 Animals|Mice|Humans|Spinocerebellar Degenerations|Vacuolar myopathy|Muscular Diseases|*Neuromuscular Junctions|Myopathy, X-Linked, with Excessive Autophagy|Guanine Nucleotide Exchange Factors|Endoplasmic Reticulum|Mutations|Phenotypes|Molecular Chaperones|*Genes, Regulator|Disease Models, Animal|*Fishes|Lysosomal Storage Diseases|Genetic Diseases, X-Linked|SIL1 protein, human|SIL1 protein, mouse 101 SIL1 30442069 Biomarkers 2018 10.1080/1354750X.2018.1539767 2 0 0 203 *Support Vector Machine|*Osteoporosis|*Turnover, Bone|Absorptiometry, Dual Energy X Ray|Bone Density|*Biomarkers|Bone 101 SIL1 30397208 Sci Rep 2018 PMC6218504 10.1038/s41598-018-34152-w 4 0 0 203 Cattle|Animals|Male|*Semen|*Proteomics|*Fertility|Sperm|Proteome|tissue-factor-pathway inhibitor 2 101 SIL1 30293566 Biochim Biophys Acta Mol Basis Dis 2018 10.1016/j.bbadis.2018.07.003 2 3 0 203 Humans|*Secretory Pathway|*HeLa Cells|Spinocerebellar Degenerations|Endoplasmic Reticulum|molecular chaperone GRP78|Heat-Shock Proteins|Guanine Nucleotide Exchange Factors|Golgi Complex|Folding, Protein|Cerebellum|Molecular Chaperones|Mutations|*Genes, Regulator|SIL1 protein, human 101 SIL1 29997438 Onco Targets Ther 2018 PMC6033116 10.2147/OTT.S167552 1 21 0 203 *Proto-Oncogene Proteins c-akt|*Glioma|MTOR protein, human|*TOR Serine-Threonine Kinases|*Signal Transduction|*Oncogene|Phosphatidylinositol 3-Kinases|Cell Proliferation|Brain Neoplasms|Apoptosis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic 101 SIL1 29773992 Front Physiol 2018 PMC5943558 10.3389/fphys.2018.00383 0 6 0 203 Animals|*RNA Interference|*Soybeans|Phylogeny|Double-Stranded RNA|*Fabaceae|Genes, Insect|Insect Proteins|Transgenic Plant|Coleoptera|Transcriptome 101 SIL1 29718201 Hum. Mol. Genet. 2018 10.1093/hmg/ddy152 5 0 0 203 Mice|Animals|Neurodegenerative Diseases|Spinocerebellar Degenerations|molecular chaperone GRP78|Heat-Shock Proteins|Guanine Nucleotide Exchange Factors|Endoplasmic Reticulum|Unfolded Protein Response|*Disease Models, Animal|Myopathy|Purkinje Cells|Cerebellar Ataxia|Folding, Protein|oxygen-regulated proteins|HSP70 Heat-Shock Proteins|Cerebellum|Heterozygote|Muscle, Skeletal|Mutations 101 SIL1 29666155 Dis Model Mech 2018 PMC5992605 10.1242/dmm.033043 3 17 0 203 *Proteostasis|*Endoplasmic Reticulum Stress|molecular chaperone GRP78|*Heat-Shock Proteins|Spinocerebellar Degenerations|*Muscle, Skeletal|Endoplasmic Reticulum|Guanine Nucleotide Exchange Factors|Mutations 101 SIL1 29406913 J. Neurol. 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Biol. 2018 10.1038/s41594-017-0012-6 5 1 0 203 Animals|molecular chaperone GRP78|*Heat-Shock Proteins|Molecular Chaperones|HSP70 Heat-Shock Proteins|HSP40 Heat-Shock Proteins|Saccharomyces cerevisiae|Adenosine Diphosphate|Protein Conformation|Adenosine Triphosphatases|Protein Binding|Adenosine Triphosphate|Fungal Proteins|Amino Acid Sequence|Binding Sites|Models, Molecular|SIL1 protein, S cerevisiae|Membrane Transport Proteins|Saccharomyces cerevisiae Proteins 101 SIL1 29312402 Front Plant Sci 2018 PMC5744475 10.3389/fpls.2017.02158 8 35 0 203 *Plant Dormancy|*Transcriptome|*Seed|Arabidopsis Proteins|Gibberellins|Arabidopsis|Gene Expression Regulation, Plant|Plant Growth Regulators|Plants, Genetically Modified|Gene Expression Profiling 101 SLC35F2 29671115 J. Clin. Immunol. 2018 10.1007/s10875-018-0499-6 8 1 0 61 Infant|Humans|Infant, Newborn|Female|*RNA|*Immunologic Deficiency Syndromes|Severe Combined Immunodeficiencies|*Proteins|Exome|*DNA|Mutation|Newborn Screening 18 SPATA7 30358834 Hum. Reprod. 2018 10.1093/humrep/dey319 8 0 0 20 Humans|Male|*Infertility, Male|CpG Islands|Sperm|Spermatogenesis|DNA Methylation|Fertility 33 SPATA7 30081822 Genet. Sel. Evol. 2018 PMC6080523 10.1186/s12711-018-0412-z 5 2 0 20 Swine|Animals|*Genome-Wide Association Study|*Semen|*Gene Regulatory Networks|Quantitative Trait Loci|*Phenotypes|Genotypes|Sus scrofa|Single Nucleotide Polymorphisms 33 SPATA7 29899041 J. Cell Biol. 2018 PMC6080925 10.1083/jcb.201712117 6 11 0 20 *Cilia|Photoreceptor Connecting Cilium|Eye Proteins|Photoreceptor Cells, Vertebrate|Carrier Proteins|Mutations 33 SPATA7 29411205 Doc Ophthalmol 2018 PMC6015729 10.1007/s10633-018-9626-1 1 0 0 20 *Retinitis Pigmentosa|Electroretinography|*Phenotypes|Visual Field Tests|Visual Fields|Retina|Visual Acuity|Tomography, Optical Coherence|Eye Proteins|Mutations 33 wdr81 30531936 Mol. Psychiatry 2018 10.1038/s41380-018-0307-y 0 1 0 101 Animals|Mice|*Neurogenesis|*Hippocampus|Neural Stem Cells|Nerve Tissue Proteins|Binding Protein|Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 2|Cerebellar Ataxia|Endosomes|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|Microcephaly|Mental Retardation|*Adaptor Proteins, Signal Transducing|Mutations|*Signal Transduction|Cells, Cultured 18 wdr81 30237576 Genet. Med. 2018 PMC6752307 10.1038/s41436-018-0138-x 13 0 0 101 Exome|Genetic Testing|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|Phenotypes|Genomics|Homozygote|Mutation|Genetic Variation 18 ADTRP 29025760 Circ Cardiovasc Genet 2017 PMC5647111 10.1161/CIRCGENETICS.116.001625 6 0 0 78 Humans|*Mucocutaneous Lymph Node Syndrome|*Immunoglobulins, Intravenous|*Genome-Wide Association Study|*Risk Factors|Polymorphism, Single Nucleotide|Genotype 18 ADTRP 28877957 FASEB J. 2017 PMC5731125 10.1096/fj.201700166RR 1 1 0 78 Animals|Humans|Zebrafish Proteins|Zebrafish|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Hematopoiesis|Myelopoiesis|Gene Knockdown Techniques 18 ADTRP 28715450 PLoS Genet. 2017 PMC5536439 10.1371/journal.pgen.1006871 4 0 0 78 Young Adult|Humans|Female|*Body Mass Index|*Uterine Fibroids|European Continental Ancestry Group|African Americans|Uterine Neoplasms|Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genetic Predisposition to Disease|Odds Ratio|Logistic Regression|Risk Factors|Genotype|Obesity|ADTRP protein, human|Membrane Proteins 18 ADTRP 28645652 Biochim Biophys Acta Mol Basis Dis 2017 PMC5859308 10.1016/j.bbadis.2017.06.015 4 35 0 78 Genome-Wide Association Study|*Atherosclerosis|*Androgens|Coronary Artery Disease|AR protein, human|Androgen Receptor|Membrane Proteins|Human Umbilical Vein Endothelial Cells|Signal Transduction|Monocyte|Cell Movement|Promoter Regions, Genetic 18 ADTRP 28341552 Biochim Biophys Acta Mol Basis Dis 2017 PMC5616168 10.1016/j.bbadis.2017.03.010 7 64 0 78 *Coronary Artery Disease|*Gene Regulatory Networks|*Genome-Wide Association Study|Endothelial Cells|*Signal Transduction|Atherosclerosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cell Proliferation|Monocytes|Up-Regulation|Transendothelial Migration|Membrane Proteins|Downregulation|Transcription Factors 18 ADTRP 28074087 Thromb J 2017 PMC5219704 10.1186/s12959-016-0124-y 0 12 0 78 lipoprotein-associated coagulation inhibitor|Genome-Wide Association Study|*Lipoproteins|Polymorphism, Single Nucleotide|*Androgens|Coronary Artery Disease|Membrane Proteins 18 ARL5B 28349920 Sci Rep 2017 PMC5368636 10.1038/srep45101 10 24 0 224 Mice|Animals|*Hippocampus|Phosphorylation|Signal Transduction|MAP Kinase Signaling System|Extracellular Signal-Regulated MAP Kinases|Mitogen-Activated Protein Kinase Kinases|Transcription Factors|Neurons|Nerve Tissue Proteins|Synapse|Regulation, Gene Action|Rgs2 protein, mouse|RGS Proteins|Ppp1r15a protein, mouse|Protein Phosphatase 1 18 ATXN8OS 29111027 J. Neurol. Sci. 2017 10.1016/j.jns.2017.08.3256 2 1 0 39 Humans|*Cerebellar Ataxia|Japan|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Spinocerebellar Ataxia 31|Spinocerebellar Ataxias|*Ataxia|Trinucleotide Repeat Expansion|Pedigree|RNA, Untranslated|Nerve Tissue Proteins|RNA, Long Noncoding|*Cohort Studies|Alleles|Homozygote 70 ATXN8OS 28229454 Acta Neurol. Scand. 2017 10.1111/ane.12744 1 0 0 39 Humans|Brazil|Spinocerebellar ataxia 8|*Ataxia, Hereditary|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Alleles|Microsatellite Marker|Pedigree|Nerve Tissue Proteins|Haplotype|RNA, Untranslated|RNA, Long Noncoding|Mutation 70 CDHR5 29088846 Oncotarget 2017 PMC5650401 10.18632/oncotarget.20507 1 3 0 51 Humans|*Carcinoma, Renal Cell|*Prognosis|Kidney Neoplasms|cadherin 5|*Cadherins|*Disease Progression|Biomarkers, Tumor|Survival Analysis|Antigens, CD|Cohort Studies 19 CHURC1 28386932 J. Fish Biol. 2017 10.1111/jfb.13308 0 0 0 49 Animals|*Real-Time Polymerase Chain Reaction|*Fishes|Genes, Essential|Gene Expression Profiling 18 CHURC1 28177073 Hum. Reprod. 2017 10.1093/humrep/dex006 6 0 0 49 Female|Humans|*Endometrium|*Gene Expression Regulation|Endometriosis|Menstrual Cycle|Embryo Implantation|Quantitative Trait Loci 18 CNTNAP5 29090003 Neural Regen Res 2017 PMC5649478 10.4103/1673-5374.215268 4 10 0 24 CNTNAP1 protein, human|*Cell Adhesion Molecules, Neuronal|*Axons|CNTNAP2 protein, human|Nerve Tissue Proteins|Neurons|Membrane Proteins|Nerve Fibers, Myelinated|Synaptic Transmission|*Nervous System Diseases|Multiple Sclerosis|Contactins 18 CNTNAP5 28601352 Eur. Urol. 2017 10.1016/j.eururo.2017.05.048 32 0 0 24 *Carcinoma, Transitional Cell|Bladder Cancer|*Urologic Neoplasms|*Genomics|Ureteral Neoplasms|Urothelium|Kidney Neoplasms|Biomarkers, Tumor|Gene Expression Profiling|Mutation|Phenotype|Genetic Predisposition to Disease 18 CPXM2 30035392 Turk. J. 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Virol. 2017 PMC5599749 10.1128/JVI.01228-17 2 0 0 63 Humans|Animals|*Simian Immunodeficiency Virus|*Glycosylation|*Mucin|*HIV Infections|Simian Acquired Immunodeficiency Syndrome|HIV-1|Viral Envelope Proteins|MUC1 protein, human|*Mucin-1|Macaca mulatta|Membrane Glycoproteins|Virion|Amino Acid Sequence 18 GALK2 28654657 PLoS ONE 2017 PMC5487050 10.1371/journal.pone.0179949 4 5 0 63 Humans|*Glycosylation|*HEK293 Cells|galactose epimerase|UDPgalactose 4-Epimerase|Galactosemias|Galactokinase|Galactose|Mutations|Uridine Diphosphate N-Acetylgalactosamine|GALK2 protein, human 18 GALK2 28440498 Mol Med Rep 2017 10.3892/mmr.2017.6474 0 2 0 63 Humans|*Human Induced Pluripotent Stem Cells|William's medium E|*Organ Preservation Solutions|Cell Differentiation|Hepatocyte|Cell Line|Cells, Cultured|Oncostatin M|Culture Media|Cell Survival|Glucose|Galactose|*Dietary Supplements|GALK2 protein, human|Galactokinase 18 GALK2 28123551 Oncol Lett 2017 PMC5245067 10.3892/ol.2016.5454 0 0 0 63 Adult|Humans|*Glucose|*Carcinoma, Hepatocellular|*Arginine|*Coculture Techniques|*Endothelial Cells|*Liver Neoplasms|*Cell Line|Hepatocytes|Cell Differentiation|*B-Lymphocytes|Culture Media|Ornithine|Galactose|Cell Death|GALK2 protein, human|Galactokinase 18 GATOR 29127423 Sci Rep 2017 PMC5681675 10.1038/s41598-017-15497-0 3 58 0 0 Animals|*Reactive Oxygen Species|RRAGA protein, human|Monomeric GTP-Binding Proteins|GTPase-Activating Proteins|mTORC1|Tumor Suppressor Proteins|TOR Serine-Threonine Kinases|Signal Transduction|Repressor Proteins|DNA Damage|Phosphorylation|Amino Acids|*Genes, Tumor Suppressor 55 GATOR 28294675 Magy Seb 2017 10.1556/1046.70.2017.1.11 0 0 0 0 Male|Humans|Aged|*Myelolipoma|*Mediastinum|Neoplasm Recurrence, Local|Adrenal Gland Neoplasms|Thoracic Surgery, Video-Assisted|Mediastinal Neoplasms|Tomography, X-Ray Computed|Contrast Agent 55 GATOR 28199315 Nature 2017 PMC5570594 10.1038/nature21378 33 33 0 0 Animals|Mice|*Signal Transduction|Mechanistic Target of Rapamycin Complex 1|Multiprotein Complexes|TOR Serine-Threonine Kinases|Monomeric GTP-Binding Proteins|Lysosome|Nuclear Proteins|GTPase-Activating Proteins|Protein Binding|Tumor Suppressor Proteins|Amino Acids|Szt2 protein, mouse|Nerve Tissue Proteins 55 gpr19 28476646 Biochim Biophys Acta Mol Cell Res 2017 10.1016/j.bbamcr.2017.05.001 4 5 0 4 Humans|CDH1 protein, human|*E Cadherin|GPRC5C protein, human|*G-Protein-Coupled Receptors|*Antigens, CD|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|MCF-7 Cells|Cell Movement|Cell Line, Tumor|Transcription Factors|Nerve Tissue Proteins|Cell Proliferation|Upregulation|Peptides|GPR19 protein, human|Receptors, Neurotransmitter 18 JPH1 29208631 Dis Model Mech 2017 PMC5818072 10.1242/dmm.029082 1 4 0 121 Animals|Mice|Humans|Drosophila melanogaster|Drosophila Proteins|Receptors, Notch|junctophilin|Membrane Proteins|Animals, Genetically Modified|Phenotype|Signal Transduction|RNA Interference|Mutations|Neurons 18 JPH1 28160492 J. Cell. Physiol. 2017 10.1002/jcp.25846 9 0 0 121 Humans|*Prognosis|*Transcriptome|*Carcinoma, Squamous Cell|*Carcinoma, Non-Small-Cell Lung|Lung Cancer|Gene Expression Profiling|Proportional Hazards Models|Biomarkers, Tumor|Kaplan-Meier Estimate|Area Under Curve|Databases, Genetic|Gene Expression Regulation, Neoplastic|Clustering|ROC Curve|Predictive Value of Tests|Multivariate Analysis|Genetic Predisposition to Disease|Epithelial Cells 18 KLHL10 28253373 PLoS ONE 2017 PMC5333912 10.1371/journal.pone.0173178 0 2 0 45 Male|Animals|Rats|*Transcriptome|ROS1 protein, human|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|*Testis|*Reproduction|Spermatogenesis|*Fishes|Gene Expression Profiling|Sperm|Gene Expression Regulation|Amino Acid Sequence|*Freshwater|Breeding|Seasons 18 LACTB 28835318 Oncol. Res. 2017 10.3727/096504017X15030178624579 2 7 0 114 Humans|Animals|*Protein, Mitochondrial|*Glioma|Brain Neoplasms|Matrix Metalloproteinase 2|Prognosis|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Matrix Metalloproteinase 9|MicroRNAs|Cell Movement|Membrane Proteins|Biomarkers, Tumor|Cell Line, Tumor|Disease Progression|LACTB protein, human|beta-Lactamases 18 LACTB 28467946 Cell Metab. 2017 10.1016/j.cmet.2017.04.027 2 0 0 114 Mitochondrial Proteins|*Cancer|Genes, Tumor Suppressor|Membrane Proteins|Gene Expression Regulation, Neoplastic|Mitochondria|Tumor Suppressor Proteins|Cell Proliferation|*Cell Division 18 LACTB 28329758 Nature 2017 PMC6246920 10.1038/nature21408 33 1 0 114 Humans|Mice|Animals|*Lipid Metabolism|Protein, Mitochondrial|*Genes, Tumor Suppressor|Mitochondria|Membrane Proteins|phosphatidylserine decarboxylase|Carboxy-Lyases|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Cycle Arrest|phosphatidylethanolamine|Phosphatidylethanolamines|Neoplasms|LACTB protein, human|beta-Lactamases 18 LMLN 28396363 Mol. Cancer Ther. 2017 10.1158/1535-7163.MCT-17-0104 6 0 0 98 Early Detection of Cancer|*Lung Cancer|*Protein Kinase Inhibitors|Carcinoma, Non-Small-Cell Lung|Erlotinib Hydrochloride|ErbB Receptors|Proto-Oncogene Proteins c-met|Quinazolines|Gefitinib|Drug Resistance, Neoplasm|Gene Amplification|Mutation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Genomics 18 MIR193A 29104111 Hum. Pathol. 2017 10.1016/j.humpath.2017.10.024 7 1 0 1 Humans|*Proto-Oncogene Proteins p21(ras)|*Colorectal Cancer|*Colon Cancer|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Adenocarcinoma|Cell Line, Tumor|Genes, Tumor Suppressor|Downregulation|Epithelial-Mesenchymal Transition|Apoptosis|Cell Cycle|KRAS protein, human 18 MIR193A 28857182 Allergy 2017 10.1111/all.13299 2 0 0 1 Child|Female|Cattle|Animals|Humans|*Milk Hypersensitivity|Skin Tests|Immunoglobulin E|DNA Methylation|Epigenesis, Genetic|MicroRNAs 18 MMRN2 28912033 Matrix Biol. 2017 10.1016/j.matbio.2017.08.003 11 2 0 55 Humans|*Cell Adhesion|multimerin|Blood Proteins|Pathological Angiogenesis|Receptors, Complement|Cell Movement|Membrane Glycoproteins|Human Umbilical Vein Endothelial Cells|Tumors|Cell Proliferation|Extracellular Matrix|*Endothelium 18 MMRN2 28671670 Oncogene 2017 PMC5671938 10.1038/onc.2017.214 15 31 0 55 Humans|Mice|Animals|*Pericytes|multimerin|*Blood Proteins|Neovascularization, Pathologic|Lectin, C-Type|CD248 protein, human|Antigens, Neoplasm|Antigens, CD|Human Umbilical Vein Endothelial Cells|Membrane Glycoproteins|Neovascularization, Physiologic|THBD protein, human|Thrombomodulin|*Ligands|Antigens, Surface|Cell Movement|Protein Binding|Cell Line, Tumor 18 MMRN2 28435016 Matrix Biol. 2017 10.1016/j.matbio.2017.04.002 16 2 0 55 *Matrix Metalloproteinase 9|multimerin|Neovascularization, Pathologic|Matrix Metalloproteinase 2|Human Umbilical Vein Endothelial Cells|Antigens, Surface|Membrane Glycoproteins|*Morphogenesis|Cell Movement|Extracellular Matrix|Tumors|Matrix Metalloproteinases|Protein Binding 18 NEXN 29253866 PLoS ONE 2017 PMC5734774 10.1371/journal.pone.0189489 5 0 0 128 Humans|Adolescent|Child|*Plakophilins|*Cardiomyopathy|*Homozygote|Arrhythmogenic Right Ventricular Dysplasia|Mutation|Genetic Testing|Genotype|Pedigree|Phenotype|Genetic Predisposition to Disease|High-Throughput Nucleotide Sequencing 40 NEXN 28368536 Endocrinology 2017 10.1210/en.2016-1960 4 2 0 128 Male|Mice|Rats|Animals|*Myocytes, Cardiac|*Hyperglycemia|*Disease Models, Animal|Epigenesis, Genetic|Cyclic AMP Response Element Modulator|Acetylation|Histones|3'-(1-butylphosphoryl)adenosine|Histone Deacetylase|*Complement Factor B|RNA, Small Interfering|Chromatin Immunoprecipitation|Gene Expression Regulation|Glucose|Crem protein, mouse|Crem protein, rat 40 NLRP9 28888400 Urol. Oncol. 2017 10.1016/j.urolonc.2017.08.004 3 0 0 79 Humans|*Inflammasomes|*Bacillus|Neoplasm Recurrence, Local|Carcinoma, Transitional Cell|Intravesical Instillation|Bladder Cancer|Disease Progression|Adjuvants, Immunologic|Genes, Regulator|mRNA 18 NLRP9 28579804 Onco Targets Ther 2017 PMC5449108 10.2147/OTT.S132680 12 6 0 79 *MicroRNAs|*Urinary Bladder Neoplasms|*Inflammasomes|*NOD-like Receptors|Gene Expression Regulation, Neoplastic|Up-Regulation|Disease Progression|*Urinary Tract 18 NLRP9 28432035 Brain Behav. Immun. 2017 10.1016/j.bbi.2017.04.010 4 2 0 79 Humans|*Inflammasomes|*Pericytes|Escherichia coli|*Receptors, Pattern Recognition|NLR Family, Pyrin Domain-Containing 3 Protein|Pro-Caspase-1|Interleukin-1beta|Toll-Like Receptor 4|Toll-Like Receptor 2|*Brain|Carrier Proteins|Signal Transduction|Cells, Cultured|mRNA 18 NSUN5 28534483 Cell Res. 2017 PMC5518879 10.1038/cr.2017.73 4 0 0 43 Humans|*Active Transport, Cell Nucleus|*mRNA|*5-Methylcytosine|RNA Transport|RNA-Binding Proteins|Nuclear Proteins|Cell Nucleus|Transcription Factors|Methyltransferases|Cytoplasm|HeLa Cells 18 PHF3 29247589 Cancer Sci. 2017 PMC5797809 10.1111/cas.13471 4 6 0 73 Humans|*Trastuzumab|*Whole Exome Sequencing|*Cardiotoxicity|*Genetic Markers|Receptor, ErbB-2|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Case-Control Study 19 PNPLA1 29081410 Cancer Biomark 2017 10.3233/CBM-170541 0 0 0 24 Humans|*Basal Cell Nevus Syndrome|*Whole Exome Sequencing|PTCH2 protein, human|Patched-2 Receptor|*Chinese|Patched-1 Receptor|Exome|Pedigree|Mutation|Genetic Linkage 42 PNPLA1 28966260 Yakugaku Zasshi 2017 10.1248/yakushi.17-00126 2 1 0 24 Epidermis|Skin|Ceramides|Ichthyosis|Ichthyosis, Lamellar|Permeability|Epidermal Cells|Lipase|Fatty Acids|Triacylglycerol|*Lipids|Acylation|Linoleic Acid 42 PNPLA1 28623042 J. Dermatol. Sci. 2017 10.1016/j.jdermsci.2017.06.002 17 0 0 24 Humans|*Skin|*Ichthyosis, Lamellar|*Ichthyoses|Epidermis|Epidermal Cells|Ceramides|*Lipids|Lipase|Lipid Metabolism|Permeability|Fatty Acids, Esterified|Phenotypes|ABCA12 protein, human|ATP-Binding Cassette Transporters|PNPLA1 protein, human 42 PNPLA1 28369476 Hum. Mol. Genet. 2017 10.1093/hmg/ddx079 10 0 0 24 Humans|Mice|Animals|*Ichthyosis, Lamellar|*Epidermis|Skin|Ceramides|*Permeability|Lipase|Lipid Metabolism|Mutation|Cell Differentiation|Extracellular Matrix|PNPLA1 protein, human|PNPLA1 protein, mouse 42 PNPLA1 28248318 Nat Commun 2017 PMC5337975 10.1038/ncomms14610 20 12 0 24 Humans|1-Acylglycerol-3-Phosphate O-Acyltransferase|Ichthyosis, Lamellar|Epidermis|Ichthyosis|Skin|Ceramides|Permeability|Lipase|Triglycerides|Acyltransferase, Diacylglycerol|*Acyltransferases|*Lipids|PNPLA1 protein, human 42 RIPPLY2 28432217 Development 2017 10.1242/dev.144345 5 1 0 35 Animals|Mice|Somites|Xenopus Proteins|Xenopus laevis|Body Patterning|*Embryonic Development|Mesoderm|Retinoic Acid|Gene Expression Regulation, Developmental|Receptors, Retinoic Acid|Embryo, Nonmammalian|Signal Transduction 31 RNASEH2C 29273853 Protein Cell 2017 PMC5966356 10.1007/s13238-017-0497-0 0 10 0 27 Humans|Mice|Animals|*Polyadenylation|3' UTR|Messenger RNA|Poly A|Transcription, Genetic|RNA, Antisense|Gene Expression Profiling|SRSF3 protein, human|Serine-Arginine Splicing Factors|Transcriptome|Computational Biology 28 RNASEH2C 29239743 Pediatr. Neurol. 2017 10.1016/j.pediatrneurol.2017.09.002 2 0 0 27 Humans|Child|Autoimmune Diseases of the Nervous System|Nervous System Malformations|*Aicardi Syndrome|Phenotype|Neurological Disorder|Mutations 28 RNASEH2C 29150899 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38522 0 1 0 27 Humans|Nervous System Malformations|Autoimmune Diseases of the Nervous System|*Aicardi Syndrome|Ribonuclease H|Exodeoxyribonucleases|Brain Diseases|Interferon|Phosphoproteins|Mutation|*Asians 28 RNASEH2C 28475458 J. Interferon Cytokine Res. 2017 PMC5439407 10.1089/jir.2017.0004 3 1 0 27 Humans|Male|Child|Female|Singleton Merten syndrome|*Odontodysplasia|*Metacarpus|*Vascular Calcification|*Muscular Diseases|*Aortic Diseases|*Osteoporosis|*Dental Enamel Hypoplasia|Interferon-Induced Helicase, IFIH1|Nervous System Malformations|Mutation|Phenotype|Bone and Bones|Mutation, Missense 28 RNASEH2C 28108556 Hum. Mol. Genet. 2017 PMC5731438 10.1093/hmg/ddx026 12 0 0 27 Humans|*Lupus Erythematosus, Systemic|SNPs|Asians|Genetic Predisposition to Disease|Genome-Wide Association Study|Genotype|European Continental Ancestry Group|Gene Expression|Cohort Studies|Hongkong|MYNN protein, human|Kruppel-Like Transcription Factors 28 SGCZ 28957450 PLoS ONE 2017 PMC5619832 10.1371/journal.pone.0185660 3 1 0 21 Humans|*Obesity|Body Mass Index|*Smoking|SNPs|*Phenotypes|Genetic Predisposition to Disease|Genome-Wide Association Study|Genetic Loci|*Tobacco Smoking|Risk Factors|*Lung Cancer 19 SGCZ 28720099 Environ Health 2017 PMC5516382 10.1186/s12940-017-0283-8 2 1 0 21 *Arsenic|*Prospective Studies|*DNA Copy Number Variations|Arsenic Poisoning|Drinking Water|*Skin Diseases|Water Supply|Environmental Exposure|Water Pollutants, Chemical|Risk Factors 19 SGCZ 28490969 Saudi J Biol Sci 2017 PMC5415145 10.1016/j.sjbs.2015.04.014 2 0 0 21 Animals|Genome-Wide Association Study|*Chickens|*Phenotype|Abdominal Fat|Single Nucleotide Polymorphism|*CD36 Antigens 19 SGCZ 28243881 Biochem. Genet. 2017 10.1007/s10528-017-9793-x 11 0 0 21 Humans|*miRNA|*Stomach Neoplasms|*Prognosis|*Introns|Adenocarcinoma|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Tumorigenesis|Downregulation|Stomach|Real-Time Polymerase Chain Reaction|MIRN383 microRNA, human 19 SGCZ 28040546 Cancer Lett. 2017 10.1016/j.canlet.2016.12.027 5 0 0 21 Humans|*Gallbladder Neoplasms|DNA Copy Number Variations|*Gallbladder|*Carcinoma, Small Cell|Carcinoma, Neuroendocrine|*Mutations|*Sequencing, Whole Genome|Sequence Analysis, DNA|Genome|Genomics|Lymphatic Metastasis 19 SLC35F2 29274137 Cancer Sci. 2017 PMC5834798 10.1111/cas.13478 7 51 0 61 Humans|*Thyroid Cancer, Papillary|MAP3K5 protein, human|*MAP Kinase Kinase Kinase 5|Thyroid Cancer|Carcinoma, Papillary|*Mitogen-Activated Protein Kinases|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|*Disease Progression|RNA, Long Noncoding|*Receptors, Growth Factor|TGFBR1 protein, human|TGFBR1|Upregulation|Cell Line, Tumor|Apoptosis|*Transforming Growth Factor 18 SLC35F2 28465296 Mol. Cancer Res. 2017 PMC5471626 10.1158/1541-7786.MCR-16-0315-T 4 27 0 61 Humans|Male|BIRC5 protein, human|*Survivin|*Drug Receptor|Quality of Life|Androgen Antagonists|Prostate Cancer|YM 155|*Naphthoquinones|*Imidazoles|*Androgens|Inhibitor of Apoptosis Proteins|Cell Line, Tumor|Xenograft Model Antitumor Assays|Cell Proliferation|Apoptosis|Antineoplastic Agents|Gene Expression Regulation, Neoplastic|Antineoplastic Combined Chemotherapy Protocols 18 SLC35F2 28350329 Molecules 2017 PMC5570559 10.3390/molecules22040539 6 18 0 61 *Neoplasms|*Precision Medicine|*Membrane Transport Proteins|Solute Carrier Proteins|Biological Transport|*Medical Oncology|Antineoplastic Agents|Amino Acids|Cell Membrane|Biochemical Phenomena 18 SLFN5 28671669 Oncogene 2017 PMC5821504 10.1038/onc.2017.205 6 30 0 77 Humans|*Glioblastoma|*Interferon|STAT1 protein, human|*STAT1 Transcription Factor|*Antiviral Agents|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Cell Transformation, Neoplastic|Cell Proliferation|*Phenotype|Cell Cycle Proteins|Signal Transduction|Tumorigenesis|Co-Repressor Proteins 18 SLFN5 28371128 Stem Cells 2017 PMC5534840 10.1002/stem.2617 18 24 0 77 Osteogenesis|*Mesenchymal Stem Cells|*Actins|*Cell Differentiation|Adipogenesis|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Cytochalasin D|Actin Cytoskeleton|Osteoblast|Cytoskeleton|PPAR gamma|Cells, Cultured|Cell Nucleus|Transcription Factors 18 SLFN5 28275687 Cell Mol Gastroenterol Hepatol 2017 PMC5331830 10.1016/j.jcmgh.2017.01.004 0 17 0 77 *Stomach Neoplasms|*Hedgehog Proteins|*Signal Transduction|Zinc Finger Protein GLI1|Cell Line, Tumor|*Inflammation 18 SNORD48 28628844 Res. Vet. Sci. 2017 10.1016/j.rvsc.2017.06.001 3 0 0 0 Pregnancy|Cattle|Female|Animals|*Buffaloes|*MicroRNAs|Sexual Maturation|Circulating MicroRNA|*Biomarkers|Pregnancy, Animal|Pregnancy Tests|Artificial Insemination|*Bison|Progesterone 18 SNORD48 28117343 Sci Rep 2017 PMC5259703 10.1038/srep41127 16 1 0 0 Humans|*miRNA|*Atrial Fibrillation|Gene Expression Profiling|Heart Atria|Reference Standards|Real-Time Polymerase Chain Reaction|Cardiac Surgical Procedures 18 SPATA7 29100828 Exp. Eye Res. 2017 PMC5756513 10.1016/j.exer.2017.10.015 6 3 0 20 Humans|Male|Mice|Animals|Adolescent|*Retinal Degeneration|Photoreceptor, Cone|Retinitis Pigmentosa|Retinal Rod Photoreceptor Cells|Rhodopsin|Leber Congenital Amaurosis|Retina|Mice, Knockout|Electroretinography|Transgenic Mouse|Eye Proteins|Mice, Inbred C57BL|Disease Models, Animal|SPATA7 protein, human|DNA-Binding Proteins|BEST1 protein, human|Bestrophins|SPATA7 protein, mouse 33 SPATA7 28966547 Mol. Vis. 2017 PMC5610811 4 0 0 20 Humans|*Leber Congenital Amaurosis|*Exome|*Whole Exome Sequencing|DNA Mutational Analysis|Pedigree|Eye Proteins|Sequencing, Next-Generation|Nicotinamide-Nucleotide Adenylyltransferase|Retinal Dystrophies|Mutation|Guanylate Cyclase|Electroretinography|Genetic Heterogeneity 33 wdr81 29249217 Can J Neurol Sci 2017 10.1017/cjn.2017.273 0 0 0 101 Humans|*Tremor|Palatal Muscles|Olivary Nucleus|Imaging, Magnetic Resonance|Phenotypes|WDR81 protein, human|Nerve Tissue Proteins 18 wdr81 28969387 Brain 2017 10.1093/brain/awx218 2 0 0 101 Animals|Humans|*Microcephaly|*Drosophila|*Neural Stem Cells|*Mutations|Lissencephaly|Pedigree|Brain|Nerve Tissue Proteins|Phenotypes|*Fibroblasts|Intellectual Disability|Sequencing, Whole Exome|*Disease Progression|WDR81 protein, human 18 wdr81 28749478 Genet. Med. 2017 10.1038/gim.2017.111 11 0 0 101 Humans|Female|Pregnancy|*Autopsy|Whole Exome Sequencing|Exome|Phenotypes|Sequence Analysis, DNA|Mutation|Chromosome Mapping|Genetic Predisposition to Disease|DNA|Fetus|Cohort Studies|KRIT1 protein, human|KRIT1 Protein|FCRL4 protein, human|Receptors, Fc|WDR81 protein, human|Nerve Tissue Proteins 18 wdr81 28556411 Ann. Neurol. 2017 10.1002/ana.24964 13 0 0 101 *Congenital Hydrocephalus|Genes, Recessive|Pedigree|Mutation|Brain|Microfilament Proteins|L1CAM 18 wdr81 28404643 J. Cell Biol. 2017 PMC5412561 10.1083/jcb.201608039 12 74 0 101 Humans|Animals|Mice|*Macroautophagy|Sequestosome-1 Protein|Ubiquitin|Ubiquitinated Proteins|Autophagy|Microtubule-Associated Proteins|Adaptor Proteins, Signal Transducing|Protein Binding|HeLa Cells|WDR81 protein, human|Nerve Tissue Proteins 18 ADTRP 27235449 Physiol. Genomics 2016 PMC5005456 10.1152/physiolgenomics.00028.2016 6 2 0 78 Humans|*Coronary Artery Disease|Endothelial Cells|*Gene Expression Regulation|*Apoptosis|*Artery, Coronary|Cell Proliferation|Downregulation|HepG2 Cells|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Cell Cycle Genes|*Cell Division|Membrane Proteins|Cell Cycle|Signal Transduction|CCND1 protein, human|Cyclin D1|ADTRP protein, human 18 ADTRP 27018888 Nat. Chem. Biol. 2016 PMC4837090 10.1038/nchembio.2051 15 12 1 78 Animals|*Hydrolases|Fatty Acids|Amino Acid Sequence|Sequence Homology, Amino Acid|Hydrolysis|Membrane Proteins|Catalysis|Lipids|Mutagenesis, Site-Directed|*Membrane|Histidine 18 ARL5B 28000370 Traffic 2016 10.1111/tra.12465 15 0 0 224 18 ARL5B 27052167 Cell Rep 2016 10.1016/j.celrep.2016.02.084 10 6 0 224 Humans|*T-Lymphocytes, Cytotoxic|*Cytoplasmic Granules|Immunological Synapses|Exocytosis|Cytotoxicity, Immunologic|*B Cells|*Synapses|Signal Transduction 18 ATXN8OS 27338628 Curr Alzheimer Res 2016 10.2174/1567205013666160622112234 32 0 0 39 Animals|*Long Non-Coding RNA|*Neurodegenerative Diseases|Central Nervous System|Brain 70 ATXN8OS 27302466 Biochim. Biophys. Acta 2016 10.1016/j.bbadis.2016.06.008 2 2 0 39 Animals|Spinocerebellar ataxia 8|*Drosophila|*Spinocerebellar Degenerations|Repeat, Expanded Trinucleotide|*RNA Recognition Motif|*RNA-Binding Domain|Spinocerebellar Ataxias|RNA, Untranslated|RNA, Long Noncoding|Nerve Tissue Proteins|Phenotype|spoonbill protein, Drosophila 70 ATXN8OS 30713928 Mov Disord Clin Pract 2016 PMC6353394 10.1002/mdc3.12312 2 0 0 39 *Huntington Disease|*Chorea|Phenotype|Syndromes 70 CAMK1G 26851501 Neurobiol. Dis. 2016 10.1016/j.nbd.2016.02.004 6 1 0 35 Mice|Animals|*Huntington Disease|histone H3 trimethyl Lys4|*Histones|Epigenesis, Genetic|Huntingtin Protein|Acetylation|*Promoter Regions, Genetic|Transcription, Genetic|Disease Models, Animal|Nerve Tissue Proteins|Protein Processing, Post-Translational 18 CDHR5 27310872 Cell Death Dis 2016 PMC5143391 10.1038/cddis.2016.163 2 21 1 51 Humans|*Enterocytes|*Colonic Neoplasms|*Colorectal Cancer|beta Catenin|*Catenins|Wnt Signaling Pathway|HCT116 Cells|Transcription Factor 7-Like 2 Protein|Downregulation|Gene Expression Regulation, Neoplastic|Cadherins|Colon|Cell Proliferation|Cell Line, Tumor|Cell Transformation, Neoplastic|Caco-2 Cells|Mesalazine 19 CDHR5 27286456 Oncotarget 2016 PMC5173119 10.18632/oncotarget.9867 2 26 1 51 Humans|Mice|Animals|*Interferon Receptor|*Cell Transformation, Neoplastic|*Intestines|*Tumorigenesis|Signal Transduction|Colorectal Carcinomas|Downregulation|Intestinal Mucosa|Gene Expression Regulation, Neoplastic|Upregulation|Interferon-gamma|Tumor Microenvironment 19 CHURC1 27588447 Am. J. Hum. Genet. 2016 PMC5011064 10.1016/j.ajhg.2016.07.001 8 1 0 49 Humans|*Adiposity|*Transcriptome|Diabetes Mellitus, Type 2|*Obesity|Body Mass Index|Visceral Fat|Absorptiometry, Dual Energy X Ray|Adipose Tissue|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Trait, Complex|Sequencing, RNA|Adipocyte|Phenotype|Genotype|Cohort Studies 18 CHURC1 27193597 Hum. Genet. 2016 PMC4947558 10.1007/s00439-016-1680-8 17 0 0 49 Humans|*Quantitative Trait Loci|*African Americans|*Diabetes Mellitus, Type 2|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|*Obesity|*Adiposity|European Continental Ancestry Group|Genetic Susceptibility|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Adipose Tissue|Gene Expression Regulation|*Muscle|Phenotypes|Genotype|Insulin|ERAP2 protein, human 18 CNTNAP5 26993346 Alzheimers Dement 2016 PMC4982482 10.1016/j.jalz.2016.01.010 28 0 1 24 *Alzheimer Disease|*Risk Factors|Apolipoproteins E|Genome-Wide Association Study|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Genotype|Atrophy 18 CPXM2 27805002 Sci Rep 2016 PMC5090242 10.1038/srep36155 8 4 1 18 18 CPXM2 27045806 PLoS ONE 2016 PMC4821617 10.1371/journal.pone.0151780 2 5 1 18 18 CPXM2 26732326 Asian-australas. J. Anim. Sci. 2016 PMC4698687 10.5713/ajas.15.0476 2 0 1 18 Animals|*Milk|*Polymorphism, Single Nucleotide|Breeding|Phenotype|Natural Selection|Quantitative Trait, Heritable|Genotype|Models, Genetic|Pedigree|Genomics 18 DIRAS1 26814130 J. Biol. Chem. 2016 PMC4813585 10.1074/jbc.M115.696831 8 6 0 155 Humans|*Guanine Nucleotide Exchange Factor|*Small GTPases|HEK293 Cells|RHOA protein, human|rhoA GTP-Binding Protein|RASGRF1 protein, human|*ras-GRF1|*Oncogenes|RAP1A protein, human|rap1 GTP-Binding Proteins|Protein Prenylation|*Oncogenesis|Protein Binding|DIRAS3 protein, human|rho GTP-Binding Proteins|DIRAS1 protein, human|GTP Phosphohydrolases|Tumor Suppressor Proteins 18 DNAJB2 28031292 Hum. Mol. Genet. 2016 PMC5409130 10.1093/hmg/ddw420 4 30 0 97 *Casein Kinase II|*Phosphorylation|Neurodegenerative Diseases|HSP40 Heat-Shock Proteins|Molecular Chaperones|AKT1 protein, human|*Protein Kinase B|Ubiquitin|Proteasome|Muscular Atrophy, Spinal|Protein Folding|Charcot-Marie-Tooth Disease|Amyotrophic Lateral Sclerosis|Mutation|Parkinsonism 32 DNAJB2 28018906 Front Mol Biosci 2016 PMC5155517 10.3389/fmolb.2016.00081 4 7 0 97 Hereditary Sensory and Motor Neuropathy|Charcot-Marie-Tooth Disease|Heat-Shock Proteins|HSP27 Heat-Shock Proteins|Mutation|Protein-Serine-Threonine Kinases 32 DNAJB2 27713507 Sci Rep 2016 PMC5054386 10.1038/srep34830 8 15 1 97 DNAJB1 protein, human|DNAJB6 protein, human|*HSP40 Heat-Shock Proteins|*HSP70 Heat-Shock Proteins|Molecular Chaperones|parkin protein|*Ubiquitin-Protein Ligases|Nerve Tissue Proteins|polyglutamine|Peptides|Parkinson Disease|Neurodegenerative Disorders 32 DNAJB2 27682256 PLoS ONE 2016 PMC5040452 10.1371/journal.pone.0157237 9 13 1 97 Cattle|Animals|*Buffaloes|*Heat Shock|*Cells, Epithelial|*Acclimatization|Mammary Glands, Animal|HSP70 Heat-Shock Proteins|*Heat Stress Disorders|Oligonucleotide Array|*Bison|Transcriptome Analysis|Transcriptome|Cells, Cultured|Up-Regulation|Signal Transduction|Downregulation|Hot Temperature|HSP90 Heat-Shock Proteins 32 DNAJB2 27611783 PLoS ONE 2016 PMC5017714 10.1371/journal.pone.0162496 4 13 1 97 Cattle|Animals|*RNA, Micro|*Circulating MicroRNA|*Lipogenesis|PTEN protein, human|*PTEN Phosphohydrolase|Bioinformatic|Gene Expression Profiling|Gene Expression Regulation|*Adipogenesis|Gene Ontology|High-Throughput Nucleotide Sequencing|Upregulation|Microarray Analysis 32 DNAJB2 27449489 Hum. Mutat. 2016 PMC5375037 10.1002/humu.23055 14 10 0 97 HSP40 Heat-Shock Proteins|*Muscular Atrophy, Spinal|*Parkinsonism|Molecular Chaperones|Ubiquitin|Protein Folding|Mutation|Protein Processing, Post-Translational|BDNF protein, human|Brain-Derived Neurotrophic Factor|Neurons|Phenotype 32 DNAJB2 26936937 Brain 2016 PMC4845254 10.1093/brain/aww028 33 31 1 97 Humans|Mice|Animals|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*DNA-Binding Proteins|*Heat-Shock Response|Frontotemporal Lobar Degeneration|Transcription Factors|Heat Shock Transcription Factor 1|TDP-43 Proteinopathy|HSP70 Heat-Shock Proteins|Heat Shock Proteins|Mice, Transgenic|Superoxide Dismutase|Inclusion Bodies|Molecular Chaperones|Neurons|Disease Models, Animal|Ubiquitin|DNAJB2 protein, human 32 DNAJB2 26752306 J Mol Diagn 2016 10.1016/j.jmoldx.2015.10.005 14 0 2 97 Humans|*Charcot-Marie-Tooth Disease|*Sequencing, Next-Generation|Hereditary Sensory and Motor Neuropathy|Mutation|Phenotype|Genetic Predisposition to Disease|Genetic Heterogeneity|Haplotype|Cell Cycle Proteins|Cohort Studies|DNAJB2 protein, human|Molecular Chaperones|HSP40 Heat-Shock Proteins 32 GATOR 27891451 J Clin Diagn Res 2016 PMC5121797 10.7860/JCDR/2016/17735.8636 0 0 0 0 *Reproducibility of Results|*Cephalometry|*Radiography, Dental|Radiography, Dental, Digital|Mandible|Maxilla|Software|Nasal Bone|Image Processing, Computer-Assisted|Sella Turcica 55 GATOR 27692174 Int Rev Cell Mol Biol 2016 10.1016/bs.ircmb.2016.05.003 12 3 0 0 Signal Transduction|Oxidative Stress|TOR Serine-Threonine Kinases|Reactive Oxygen Species|AMP-Activated Protein Kinases|*Biochemical Phenomena|Mechanistic Target of Rapamycin Complex 1|Heat-Shock Proteins|Nuclear Proteins|Antioxidants|Rapamycin 55 gpr19 27716579 Aquat. Toxicol. 2016 PMC5274700 10.1016/j.aquatox.2016.09.019 3 6 0 4 Animals|*Zebrafish|Zebrafish Proteins|NFE2L2 protein, human|NF-E2-Related Factor 2|*Oxidative Stress|Embryo, Nonmammalian|*Oxidation-Reduction|Embryonic Development|Gene Expression Regulation, Developmental|Pro Oxidants|Antioxidants|GA-Binding Protein Transcription Factor|Animals, Genetically Modified|Larvae 18 gpr19 26934370 PLoS ONE 2016 PMC4775022 10.1371/journal.pone.0150846 13 23 1 4 *Plasmalogens|*Proto-Oncogene Proteins c-akt|*Signal Transduction|GPRC5C protein, human|*Receptors, G-Protein-Coupled|*Neurons|Phosphorylation|Extracellular Signal-Regulated MAP Kinases|Cell Death|Cell Survival|Cell Line, Tumor 18 gpr19 26739651 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2016 PMC4867374 10.1152/ajpregu.00511.2015 18 0 1 4 Male|Animals|Rats|*Drinking Water|GPRC5C protein, human|*Receptors, G-Protein-Coupled|Thirst|*Brain|Deprivation, Water|Nerve Tissue Proteins|Injections, Intraventricular|Peptide Hormones|Drinking Behavior|Signal Transduction|Angiotensin II|Medial Hypothalamus|mRNA|Protein Binding|GPR19 protein, rat|Receptors, Neurotransmitter 18 KLHL10 27052834 Dev. Cell 2016 10.1016/j.devcel.2016.02.025 14 2 1 45 Male|Animals|*Citric Acid Cycle|*Mitochondria|Caspases|Drosophila|Spermatids|Drosophila Proteins|Drosophila melanogaster|*Cell Death|Spermatozoa|Apoptosis|Succinate-CoA Ligases|Enzyme Activation|*Proteolysis|Cell Differentiation|Cytoplasm 18 KLHL40 27762439 Prenat. Diagn. 2016 10.1002/pd.4949 2 0 0 71 Pregnancy|Female|Humans|Pena Shokeir syndrome, type 1|*Prenatal Diagnosis|Arthrogryposis|*Sequencing, Next-Generation|*Mutations|*Fetuses|Pedigree|KLHL40 protein, human|Muscle Proteins 19 KLHL40 27528495 Neuromuscul. Disord. 2016 10.1016/j.nmd.2016.07.011 2 0 0 71 Humans|Female|Child|*Myopathies, Nemaline|Muscle Proteins|Muscle, Skeletal|Mutation|Phenotypes|Hypotonia|KLHL40 protein, human 19 KLHL40 27074222 Ann. Neurol. 2016 PMC4911820 10.1002/ana.24654 17 3 0 71 *Sarcomeres|*Myopathy|Myopathies, Nemaline|Muscle Contraction|Muscle Weakness|Muscle Proteins|*Actin Cytoskeleton|Muscle, Skeletal|*Mutation 19 KLHL40 26754003 J. Neurol. 2016 10.1007/s00415-015-8015-x 2 0 0 71 Humans|Infant|*Myopathies, Nemaline|*Cholinesterase Inhibitors|Muscle Proteins|Muscle, Skeletal|Mutations|Muscle Weakness|Hypotonia|KLHL40 protein, human 19 MESP2 27894818 Dev. Biol. 2016 PMC5209264 10.1016/j.ydbio.2016.11.009 0 30 0 93 Mice|Animals|Prospective Studies|Somite|Mesoderm|Body Patterning|DLL3 protein, human|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Receptors, Notch|Transcription Factors|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|*Bone and Bones|In Situ Hybridization|Signal Transduction|Embryonic Development|Vertebrae|Ephrin-B2|Lfng protein, mouse 95 MESP2 27385009 Development 2016 PMC6514405 10.1242/dev.133173 0 0 0 93 Mice|Animals|*Somites|*Zebrafish|Zebrafish Proteins|Body Patterning|Mesoderm|Gene Expression Regulation, Developmental|Embryonic Development|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors 95 MESP2 27185833 J. Cell Biol. 2016 PMC4878090 10.1083/jcb.201505082 0 52 1 93 Mice|Animals|Embryonic Stem Cell|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Mesoderm|Cell Lineage|Heart|Myocardium|Transcription Factors|Cell Migration|Embryonic Development|Mesp1 protein, mouse|Prickle1 protein, mouse|Adaptor Proteins, Signal Transducing|LIM Domain Proteins 95 MESP2 27185831 J. Cell Biol. 2016 PMC4878095 10.1083/jcb.201604121 0 7 1 93 Mesoderm|Progenitor Cell|Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|Transcription Factors|Gene Expression Regulation, Developmental|Myocardium|Heart|Cell Migration 95 MMRN2 26939791 FASEB J. 2016 10.1096/fj.201500122R 15 0 0 55 Humans|Mice|Animals|*Lectin, C-Type|Neovascularization, Pathologic|Cell Adhesion Molecules|Human Umbilical Vein Endothelial Cells|Membrane Proteins|Endopeptidases|RNA, Small Interfering|*Morphogenesis|*Catalysis|RHBDL2 protein, human|Serine Proteases|CLEC14A protein, human|RHBDL2 protein, mouse 18 MTCH1 27485725 BMC Genomics 2016 PMC4970254 10.1186/s12864-016-2850-8 6 28 1 78 Swine|Animals|*RNA, Micro|*mRNA|*Muscle Fibers, Skeletal|Gene Regulatory Networks|Gene Expression Profiling|Muscle, Skeletal|*Mitochondria|*Respiratory Muscles|*Intercostal Muscles 18 PHF3 27184836 Cell Rep 2016 PMC4893159 10.1016/j.celrep.2016.04.047 42 21 1 73 Proteomics|cohesins|Cell Cycle Proteins|DNA Damage|DNA Repair|Ataxia Telangiectasia Mutated Proteins|Phosphorylation|Nuclear Proteins|Transcription, Genetic|Ultraviolet Rays|Proteasome Endopeptidase Complex|Protein Binding|Chromosomal Proteins, Non-Histone 19 PHF3 26939788 Sci Rep 2016 PMC4778017 10.1038/srep22395 1 2 1 73 Pregnancy|Animals|Humans|Female|*Placental Mammals|Sodium-Potassium-Exchanging ATPase|Amino Acid Sequence|Transcription Factor|Nuclear Envelope|Isoforms|Membrane Proteins|cDNA Libraries|Chicken|ATP1B4 protein, human 19 RASEF 27724860 BMC Genomics 2016 PMC5057473 10.1186/s12864-016-3145-9 0 10 1 44 Male|*Testis|*GTPase|Spermatogenesis|Spermatids|Amino Acid Sequence|Nuclear Proteins 18 RIPPLY2 27894818 Dev. Biol. 2016 PMC5209264 10.1016/j.ydbio.2016.11.009 0 30 0 35 Mice|Animals|Prospective Studies|Somite|Mesoderm|Body Patterning|DLL3 protein, human|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Receptors, Notch|Transcription Factors|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|*Bone and Bones|In Situ Hybridization|Signal Transduction|Embryonic Development|Vertebrae|Ephrin-B2|Lfng protein, mouse 31 RIPPLY2 27769046 Oncotarget 2016 PMC5370036 10.18632/oncotarget.12738 3 0 0 35 Humans|*Takayasu Arteritis|Genome-Wide Association Study|*Asian Continental Ancestry Group|FCGR2A protein, human|*Receptors, IgG|FCGR3A protein, human|Single Nucleotide Polymorphisms|Allele|Genetic Predisposition to Disease|Genotype|Gene Frequency|Genetic Association Studies|Linkage Disequilibrium|Case-Control Studies|Phenotype 31 RNASEH2C 27988520 Oncology 2016 10.1159/000452281 7 0 0 27 *B-DNA|*Colorectal Cancer|*Colon Cancer|Prognosis|Biomarkers, Tumor|*Endonucleases|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|*Disease Progression|RNA, Messenger|Real-Time Polymerase Chain Reaction|*Gene Expressions 28 RNASEH2C 27643693 Neuropediatrics 2016 10.1055/s-0036-1592307 12 0 0 27 *SAM Domain and HD Domain-Containing Protein 1|*Interferon-Induced Helicase, IFIH1|Nervous System Malformations|three prime repair exonuclease 1|*Exodeoxyribonucleases|*Phenotypes|Autoimmune Diseases of the Nervous System|*Mutations|*Phosphoproteins|*Aicardi Syndrome|Ribonuclease H|Adenosine Deaminase|Monomeric GTP-Binding Proteins|Brain Diseases|Interferon 28 RNASEH2C 27411419 Turk. J. Pediatr. 2016 1 0 0 27 Humans|Male|*Siblings|three prime repair exonuclease 1|*Exodeoxyribonucleases|Nervous System Malformations|Autoimmune Diseases of the Nervous System|*Phosphoproteins|*Mutation|*Aicardi Syndrome|Ribonuclease H|SAM Domain and HD Domain-Containing Protein 1|Phenotype|Monomeric GTP-Binding Proteins|Brain Diseases|White Matter|Calcinosis 28 RNASEH2C 26880576 J. Exp. Med. 2016 PMC4813680 10.1084/jem.20151464 52 7 1 27 Mice|Animals|*Catalytic Domain|Autoimmune Diseases of the Nervous System|MB21D1 protein, human|*Nucleotidyltransferases|Nervous System Malformations|Ribonuclease H|ribonuclease B|*RNase|*Aicardi Syndrome|Mice, Knockout|Mutation|Interferon|DNA Damage|Disease Models, Animal|*Chromogranin A|Immunity, Innate 28 SGCZ 27660274 Mol. Neurobiol. 2016 10.1007/s12035-016-0102-1 3 0 0 21 Humans|*Depressive Disorder, Major|*Bipolar Disorder|*Chromosomes, Human, Pair 8|*Schizophrenia|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genome-Wide Association Study|Genotype|Asian Continental Ancestry Group|CSMD1 protein, human|Membrane Proteins|Case-Control Studies|Cohort Studies 19 SLC35F2 27735941 Cell Death Dis 2016 PMC5133961 10.1038/cddis.2016.257 12 32 1 61 Humans|BIRC5 protein, human|*Survivin|YM 155|*Naphthoquinones|*Imidazoles|Inhibitor of Apoptosis Proteins|Cell Line, Tumor|Antineoplastic Agents|Neuroblastoma|Apoptosis|Xenograft Model Antitumor Assays|Caspase 3|Cell Survival|Drug Resistance, Neoplasm|Cell Proliferation|RNAi|Downregulation|SLC35F2 protein, human 18 SLFN5 27032393 J. Gastroenterol. 2016 PMC5045746 10.1007/s00535-016-1202-4 7 3 0 77 Humans|Mice|Animals|*Stomach Neoplasms|*Metaplasia|Gastritis, Atrophic|Gastric Mucosa|Helicobacter Infections|Helicobacter pylori|Precancerous Conditions|Disease Progression|Biomarkers|Risk Factor|Gastroscopy 18 SNORD48 27930363 Clin. Chem. Lab. Med. 2016 10.1515/cclm-2016-0756 7 0 0 0 Adult|Humans|Neoplasm Recurrence, Local|*Colorectal Neoplasms|*MicroRNAs|*Adenocarcinoma|Prognosis|*Upregulation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Transcriptional Activation|Kaplan-Meier Estimate|Real-Time Polymerase Chain Reaction|*Chronic Disease|*Relapse|MIRN16 microRNA, human 18 SNORD48 27044381 Tumour Biol. 2016 10.1007/s13277-016-5023-0 15 0 0 0 Humans|*Colorectal Cancer|*Adenocarcinoma|Prognosis|Gene Expression Regulation, Neoplastic|MicroRNAs|Biomarkers, Tumor|Neoplasm Recurrence, Local|Upregulation|Real-Time PCR, Quantitative|Kaplan-Meier Estimate|MIRN96 microRNA, human 18 SNORD48 27419385 J. Cell. Mol. Med. 2016 PMC5134371 10.1111/jcmm.12927 8 0 1 0 Humans|Female|*RNA, Micro|*Small Non-Coding RNA|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Real-Time Polymerase Chain Reaction|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Reference Standards|Prognosis|Ovary 18 SPATA7 27717089 Clin. Genet. 2016 10.1111/cge.12872 8 0 0 20 Humans|DNA Copy Number Variations|Retrospective Studies|*Homozygote|Genes, Recessive|Oligonucleotide Array Sequence Analysis|Uniparental Disomy|*Family|Polymorphism, Single Nucleotide|FKBP10 protein, human|Tacrolimus Binding Proteins|SPATA7 protein, human|DNA-Binding Proteins|SRD5A2 protein, human|Membrane Proteins|3-Oxo-5-alpha-Steroid 4-Dehydrogenase 33 SPATA7 26854980 Ophthalmic Genet. 2016 PMC4988809 10.3109/13816810.2015.1130154 4 0 0 20 *Cone-Rod Dystrophies|*Retinitis Pigmentosa|Electroretinography|*Phenotype|Visual Field Tests|Visual Fields|Visual Acuity|Retinal Degeneration|Tomography, Optical Coherence|Mutations|Pedigree 33 TESMIN 27529658 Cancer 2016 PMC5115939 10.1002/cncr.30241 2 5 0 39 Child|Humans|Genome-Wide Association Study|*Exome|*Hispanics|*Acute Lymphoblastic Leukemia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|DNA-Binding Proteins|Genotype|Transcription Factors|European Continental Ancestry Group|*Maternal Effects|Case-Control Studies|Incidence|B-Lymphocytes 18 TESMIN 27142620 BMC Genomics 2016 PMC4855317 10.1186/s12864-016-2666-6 5 23 1 39 *Phytoplankton|*Iron|*Eukaryotes|*Green Algae|Sequence Alignment|Plant Proteins|*Eukaryotic Cells|Amino Acid Sequence 18 wdr81 27412792 Traffic 2016 10.1111/tra.12365 0 1 0 101 Humans|HeLa Cells|Endosomes|Lysosomes|Protein Transport|Endocytosis|Confocal Microscopy|Microscopy, Fluorescence|WDR81 protein, human|Nerve Tissue Proteins 18 wdr81 27126989 Traffic 2016 PMC5025723 10.1111/tra.12409 4 28 1 101 Humans|*Bone Marrow Stromal Antigen 2|vpu protein, Human immunodeficiency virus 1|Human Immunodeficiency Virus Proteins|Viral Regulatory and Accessory Proteins|HIV-1|*Protein Transport|Virus Release|Virion|Endosomes|Cell Membrane|HIV Infections|Antigens, CD|GPI-Linked Proteins|Lysosomes|beta-Transducin Repeat-Containing Proteins|HeLa Cells|Endocytosis|Downregulation 18 wdr81 26783301 J. Cell Biol. 2016 PMC4738380 10.1083/jcb.201506081 13 65 2 101 Animals|phosphatidylinositol 3-phosphate|Phosphatidylinositol 3-Kinases|*Endosomes|*Phosphatidylinositol Phosphates|Caenorhabditis elegans|Caenorhabditis elegans Proteins|*Transport Vesicles|rab GTP-Binding Proteins|Vesicular Transport Proteins|Protein Transport|Endocytosis|EGFR protein, human|Epidermal Growth Factor Receptor|SORF-2 protein, C elegans|Carrier Proteins|SORF-1 protein, C elegans 18 ADTRP 26375920 PLoS ONE 2015 PMC4574160 10.1371/journal.pone.0137547 7 2 1 78 Humans|Genome-Wide Association Study|*Coronary Artery Disease|*Asian Continental Ancestry Group|SNPs|Genetic Predisposition to Disease|Alleles|Genetic Association Studies|Gene Frequency|Genotype|Case-Control Studies|Haplotype|Risk Factors|Ethnic Groups|*Promoter Regions, Genetic|Lipids|ADTRP protein, human|Membrane Proteins 18 ADTRP 25928384 Lipids Health Dis 2015 PMC4436167 10.1186/s12944-015-0026-1 1 1 0 78 Humans|*Coronary Artery Disease|*Hyperuricemia|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Alleles|Case-Control Studies|Ethnic Groups|Risk Factors 18 ADTRP 25595457 FEBS Lett. 2015 10.1016/j.febslet.2015.01.002 8 0 2 78 Humans|*Coronary Artery Disease|*Macrophages|*Gene Expression Regulation|Atherosclerosis|PPAR gamma|Gene Expression|Cells, Cultured 18 ARL5B 25898167 Dev. Cell 2015 PMC4788105 10.1016/j.devcel.2015.02.011 84 13 12 224 Humans|*Lysosome|Kinesin|ADP-Ribosylation Factors|Microtubules|Multiprotein Complexes|HeLa Cells 18 ARL5B 25795912 Biol Open 2015 PMC4400590 10.1242/bio.201410975 6 11 1 224 Humans|Animals|HeLa Cells|Drosophila melanogaster|*Golgi Apparatus|*Endosome|trans Golgi Network|GOLPH3 protein, human|Protein Transport|Vesicular Transport Proteins|SNARE Proteins|Protein Binding|*Small G-Proteins|ARL5B protein, human|ADP-Ribosylation Factors 18 ATXN8OS 26077168 Parkinsonism Relat. Disord. 2015 PMC4572894 10.1016/j.parkreldis.2015.06.004 0 0 0 39 Humans|*Essential Tremor|Spinocerebellar Ataxia 12|Spinocerebellar Ataxia 1|Spinocerebellar Ataxia 17|Spinocerebellar Ataxia 10|*Genetic Testing|Spinocerebellar ataxia 8|*Ataxia, Hereditary|Trinucleotide Repeat Expansion|Trinucleotide Repeats|Gene Frequency|DNA Repeat Expansion|Nerve Tissue Proteins|ATXN10 protein, human|Ataxin-10 70 CAMK1G 25677198 Amyotroph Lateral Scler Frontotemporal Degener 2015 10.3109/21678421.2014.999790 0 0 0 35 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Chinese|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Frequencies, Allele|Genotype|Genome-Wide Association Study|China 18 CDHR5 26463459 Sci Rep 2015 PMC4604459 10.1038/srep15238 2 9 1 51 Humans|*Polycystic Kidney, Autosomal Dominant|*Prognosis|*Epigenesis, Genetic|*Cyst|DNA Methylation|Promoter Regions, Genetic|Cell Line|Biomarkers 19 CDHR5 25972897 Gastroenterol Res Pract 2015 PMC4417986 10.1155/2015/317093 1 3 0 51 Humans|*Down-Regulation|*Colorectal Cancer|DNA Methylation|Epigenesis, Genetic|Promoter Regions, Genetic|histone H3 trimethyl Lys4|Histones|Decitabine|Gene Expression Regulation, Neoplastic|Gene Silencing|*Epigenetic|Adenoma|HT29 Cell|Cadherins|mRNA|Cell Transformation, Neoplastic 19 DIRAS1 26635085 Mol. Neurobiol. 2015 10.1007/s12035-015-9550-2 1 2 0 155 Humans|Animals|Mice|*Zebrafish|*Trigeminal Ganglion|*Neurite Outgrowth|*Neurons|RAC1 protein, human|ras Related C3 Botulinum Toxin Substrate 1|NeuroD protein|Nerve Tissue Proteins|Neurites|PAK1 protein, human|p21-Activated Kinases|Signal Transduction|Hippocampus|Cells, Cultured|protein kinase N|Protein Kinase C|Downregulation|Basic Helix-Loop-Helix Transcription Factors 18 DNAJB2 25847151 Neurosci. Lett. 2015 10.1016/j.neulet.2015.04.001 28 6 2 97 *Mitochondrial Dynamics|Charcot-Marie-Tooth disease, Type 4A|Charcot Marie Tooth Disease|Charcot-Marie-Tooth disease, Type 2K|Charcot-Marie-Tooth disease, Type 2A|Inherited Peripheral Neuropathy|GTP Phosphohydrolases|Mitochondrial Proteins|Mutations|Membrane Proteins|Mitochondria|Hereditary Sensory and Autonomic Neuropathies|Axonal Transport|Nerve Tissue Proteins|Heterozygote|Axons|Nerves, Peripheral|Phenotype 32 GALK2 25683148 J. Cell. Biochem. 2015 10.1002/jcb.25139 4 0 2 63 Humans|*Human Induced Pluripotent Stem Cells|*Cell Differentiation|Hepatocytes|Cell Line|Cell Culture Techniques|Oncostatin M|Culture Media|Cell Survival|AFP protein, human|alpha Fetoprotein|Glucose|Galactose|Transcription Factors|CYP3A4|Pyruvate|Dietary Supplements|GALK2 protein, human|Galactokinase 18 gpr19 26384023 PLoS ONE 2015 PMC4575141 10.1371/journal.pone.0138463 28 4 1 4 Animals|Cricetinae|CHO Cells|Cricetulus|GPR68 protein, human|*G-Protein-Coupled Receptors|ADGRG1 protein, human|GPR15 protein, human|GPR39 protein, human|GPR32 protein, human|GPR17 protein, human|Receptors, Peptide|Forskolin|Cyclic AMP|Signal Transduction|Gene Expression|Reporter Gene 18 JPH1 26374336 J. Muscle Res. Cell. Motil. 2015 10.1007/s10974-015-9421-5 16 0 3 121 *Sarcoplasmic Reticulum|*Skeletal Muscle Fibers|triadin|Ryanodine Receptor|Calsequestrin|junctophilin|Membrane Proteins|Sarcolemma|Muscle Contraction|Calcium Signaling|Myofibrils|Excitation Contraction Coupling|Calcium-Binding Proteins|Muscle, Skeletal|Calcium|Endoplasmic Reticulum 18 JPH1 26098909 PLoS ONE 2015 PMC4476619 10.1371/journal.pone.0128909 0 5 0 121 Humans|Sheep|Dogs|Animals|*Genome-Wide Association Study|*Entropion|*Genome|Genotype|Breeding|Phenotype|Sheep, Domestic|Genetics, Population|Polymorphism, Single Nucleotide|Genomics|Genetic Markers|SLC2A9 protein, human|Glucose Transport Proteins, Facilitative|KCNB1 protein, human|Shab Potassium Channels 18 KLHL10 26178295 J. Obstet. Gynaecol. Res. 2015 10.1111/jog.12765 14 0 1 45 Humans|Male|*Infertility, Male|Azoospermia|Chromosomes, Human, Y|Spermatogenesis|Chromosome Deletion 18 KLHL40 26578207 Orphanet J Rare Dis 2015 PMC4650299 10.1186/s13023-015-0364-0 16 1 1 71 Humans|Pregnancy|Female|Infant, Newborn|*High-Throughput Nucleotide Sequencing|*Neuromuscular Diseases|Sequencing, Whole Exome|Genetic Testing|Arthrogryposis|*Birth|*Cohort Studies|Mutation|Muscle Proteins 19 KLHL40 25940086 J. Biol. Chem. 2015 PMC4463473 10.1074/jbc.M114.629956 5 6 0 71 Mice|Animals|*Muscle Development|*Kelch Repeat|*BTB-POZ Domain|Transcription Factor DP1|E2F Transcription Factors|*Protein Binding|E2F1 Transcription Factor|Retinoblastoma Protein|Cell Cycle Proteins|*Muscle, Skeletal|Promoter Regions, Genetic|Transcriptional Activation|Base Sequence 19 KLHL40 25774500 J. Clin. Invest. 2015 PMC4396495 10.1172/JCI80115 24 5 5 71 Mice|Animals|Nemaline Myopathy|Sarcomeres|Actin|Muscle, Skeletal|Muscle Proteins|Transcription Factor SRF|Microfilament Proteins|Muscle Contraction|myocardin|Trans-Activators|Nuclear Proteins|Transcription Factors|Mutation|leiomodin-3 protein, mouse 19 KLHL40 25721947 Brain Dev. 2015 10.1016/j.braindev.2015.02.002 0 0 0 71 Humans|Male|Child, Preschool|*Myopathies, Nemaline|*Mutation|Muscle Proteins|Muscular Diseases|Muscle, Skeletal|KLHL40 protein, human 19 LACTB 26603571 Arch. Biochem. Biophys. 2015 10.1016/j.abb.2015.11.007 5 6 1 114 *RNA, Micro|CCL2 protein, human|*Chemokine CCL2|*Macrophages|*Lipopolysaccharides|3' Untranslated Regions|Inflammation|Signal Transduction|Atherosclerosis 18 LMLN 25858378 Shanghai Kou Qiang Yi Xue 2015 0 0 0 98 Humans|*Carcinoma, Squamous Cell|Diffusion Magnetic Resonance Imaging|*Mouth Neoplasms|*Lymph Nodes|Lymphatic Metastasis|Head and Neck Neoplasms|Sensitivity and Specificity|ROC Curve|Diagnosis, Differential 18 MESP2 26088191 Protein Cell 2015 PMC4506290 10.1007/s13238-015-0176-y 0 12 0 93 Animals|Mesoderm|*Pluripotent Stem Cells|*Cell Differentiation|Somites|Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|Helix Loop Helix Motif|Gene Expression Regulation, Developmental|Body Patterning|Heart|Embryo, Mammalian|*Mammals|Embryonic Development|Signal Transduction 95 MESP2 25981852 J. Physiol. (Lond.) 2015 PMC4532534 10.1113/JP270369 22 8 3 93 Mice|Animals|*Rett Syndrome|*Astrocytes|*Carbon Dioxide|Methyl-CpG-Binding Protein 2|*Disease Models, Animal|Medulla Oblongata|Respiration|Brain|Cells, Cultured|Cerebral Cortex 95 MESP2 25765547 BMC Genomics 2015 PMC4336704 10.1186/s12864-015-1240-y 6 4 1 93 Swine|Humans|Animals|Mice|*Phenotype|Quantitative Trait Loci|Genome-Wide Association Study|Chromosome Mapping|Quantitative Trait, Heritable|Genotype|Polymorphism, Single Nucleotide 95 MESP2 25659135 PLoS ONE 2015 PMC4319916 10.1371/journal.pone.0117055 0 2 5 93 Adult|Dogs|Humans|Animals|Spondylocostal dysostosis, autosomal recessive|*Dysostoses|*Exons|Jarcho-Levin syndrome|Abnormalities, Multiple|Hernia, Diaphragmatic|Mutation|Pedigree|Spine|Genetic Testing|Basic Helix-Loop-Helix Transcription Factors|Phenotype|Gene Mapping|Bone and Bones|Australia 95 MESP2 25641698 Dev. Biol. 2015 10.1016/j.ydbio.2015.01.020 9 3 2 93 Mice|Animals|Somites|Transcription Factors|Mesoderm|Receptors, Notch|Basic Helix-Loop-Helix Transcription Factors|Repressor Proteins|Gene Expression Regulation, Developmental|Mice, Transgenic|Embryonic Development|Signal Transduction 95 MESP2 25629977 PLoS ONE 2015 PMC4309530 10.1371/journal.pone.0117410 0 61 0 93 *Cyclosporine|*Cell Differentiation|Embryonal Carcinoma Stem Cells|*Organogenesis|Embryoid Body|Cell Lineage|Mesoderm|Homeodomain Proteins|Wnt Signaling Pathway|Myocytes, Cardiac|Cell Line|Dimethylsulphoxide 95 MIR193A 26586227 J Mol Diagn 2015 10.1016/j.jmoldx.2015.07.008 5 0 0 1 Humans|Male|Female|miRNA|Biomarkers|*Body Fluids|*Diagnostic Tests, Routine|MIRN448 microRNA, human 18 MIR193A 25552301 Brain 2015 PMC4408428 10.1093/brain/awu373 40 0 6 1 Humans|*Epilepsy, Temporal Lobe|*Sclerosis|*DNA Methylation|*B-DNA|Pilot Projects|Hippocampus|Gene Expression Regulation|RNA, Micro|Neurons|Promoter Regions, Genetic|Epilepsy|Epigenesis, Genetic|Neuronal Plasticity|MIRN876 microRNA, human 18 MMRN2 26544852 PLoS ONE 2015 PMC4636393 10.1371/journal.pone.0141876 16 2 1 55 Humans|Female|*Chromatography, Liquid|*Proteomics|*Biomarkers, Tumor|*Tandem Mass Spectrometry|Proteome|Prognosis|*Body Fluids 18 MMRN2 26364800 Acta Pharmacol. Sin. 2015 PMC4648174 10.1038/aps.2015.73 15 81 1 55 *Angiogenesis Inhibitors|Neovascularization, Pathologic|Cancer 18 MMRN2 25745997 Oncogene 2015 PMC4724939 10.1038/onc.2015.34 19 10 3 55 Humans|Mice|Animals|Cell Adhesion Molecules|Lectins, C-Type|Neovascularization, Pathologic|*Neoplasms|*Morphogenesis|Human Umbilical Vein Endothelial Cells|Neovascularization, Physiologic|Membrane Glycoproteins|Antigens, Surface|Cell Movement|Biomarkers, Tumor|Signal Transduction|Gene Expression Regulation, Neoplastic|CLEC14A protein, human 18 MTCH1 26692143 Gene 2015 10.1016/j.gene.2015.12.014 1 2 0 78 Humans|*Presenilin-1|HEK293 Cells|*Gene Expression Regulation|Mitochondrial Membrane, Outer|Binding Sites|Promoter Regions, Genetic|Early Growth Response Protein 1|Apoptosis|Transcriptional Activation|Cell Differentiation|Transfection|Chromatin Immunoprecipitation 18 NLRP9 26282902 Urol. Oncol. 2015 10.1016/j.urolonc.2015.07.012 11 0 0 79 Humans|KRT20 protein, human|*Keratin-20|*Urinary Bladder Neoplasms|*Inflammasomes|*Messenger RNA|Carcinoma, Transitional Cell|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|BIRC5 protein, human|Survivin|Neoplasm Proteins|Neoplasm Recurrence, Local|Disease Progression|*Rare Diseases|Genes, Regulator 18 NLRP9 26083549 J. Neurochem. 2015 10.1111/jnc.13197 14 0 2 79 Humans|*Inflammasomes|*NOD-like Receptors|*Endothelial Cells|Nod1 Signaling Adaptor Protein|Nod2 Signaling Adaptor Protein|Muramyl Dipeptide|Caspase 1|Immunity, Innate|Interleukin-1beta|Lipopolysaccharides|Interleukins|Caspases|Cytokines|Signal Transduction|Cells, Cultured 18 NSUN5 26268215 BMC Plant Biol. 2015 PMC4535395 10.1186/s12870-015-0580-8 26 9 1 43 *5-Methylcytosine|*tRNA|*RNA, Ribosomal|Arabidopsis|RNA, Plant|Chloroplast|Methylation|Transcriptome|RNA, Messenger|Methyltransferases|Mitochondria|Cell Nucleus|Brassica rapa 18 NSUN5 26196062 Gene 2015 10.1016/j.gene.2015.07.060 0 0 0 43 Humans|Animals|*Segmental Duplications, Genomic|*Primate|Gene Duplication|Evolution, Molecular|Hominidae|Phylogeny|Genome, Human|Pseudogenes|Genomics|*Chromosome 11|Pan troglodytes|Gene Dosage|Sequence Analysis, DNA|*Chromosome Structures|Gene Cluster|FKBP6 protein, human|Tacrolimus Binding Proteins|TRIM50 protein, human 18 NSUN5 25635753 Nat Commun 2015 PMC4317494 10.1038/ncomms7158 58 5 6 43 *Methylation|*Longevity|RNA, ribosomal, 25S|*RNA, Ribosomal|Saccharomyces cerevisiae|Ribosome|Saccharomyces cerevisiae Proteins|Ribosomal Proteins|Methyltransferases|Protein Biosynthesis|*Protein Processing, Post-Translational 18 PHF3 26173551 Alcohol. Clin. Exp. Res. 2015 PMC5587504 10.1111/acer.12786 6 0 0 73 Humans|*Alcoholism|*Genome Wide Association Analysis|Genetic Predisposition to Disease|European Continental Ancestry Group|Polymorphism, Single Nucleotide|African Americans|Case-Control Studies|Membrane Proteins 19 PHF3 25991709 Physiol. Genomics 2015 PMC4525077 10.1152/physiolgenomics.00114.2014 9 0 0 73 Humans|Mice|Animals|*Quantitative Trait Locus|*Chromosomes, Human, Pair 1|Genome-Wide Association Study|Chromosome Mapping|Chromosomes, Mammalian|Mice, Inbred C57BL|Phenotypes|Ethanol|Gene Expression Profiling 19 PHF3 25944688 Oncotarget 2015 PMC4537035 10.18632/oncotarget.3791 7 1 0 73 Humans|*Glioblastoma|*Prognosis|Retrospective Studies|Reproducibility of Results|Brain Neoplasms|peptide B|Survival Analysis|MAGEA3 protein, human|Antigens, Neoplasm|Neoplasm Proteins 19 RIPPLY2 26238661 Am. J. Med. Genet. A 2015 PMC4837953 10.1002/ajmg.a.37263 9 3 0 35 Humans|Male|Klippel Feil syndrome recessive type|*Klippel-Feil Syndrome|Cervical Vertebrae|Pedigree|Homozygote|Mutations|*Signal Transduction 31 RIPPLY2 25641698 Dev. Biol. 2015 10.1016/j.ydbio.2015.01.020 9 3 2 35 Mice|Animals|Somites|Transcription Factors|Mesoderm|Receptors, Notch|Basic Helix-Loop-Helix Transcription Factors|Repressor Proteins|Gene Expression Regulation, Developmental|Mice, Transgenic|Embryonic Development|Signal Transduction 31 SGCZ 26611327 BMC Genomics 2015 PMC4661944 10.1186/s12864-015-2213-x 14 2 1 21 Male|Female|Mice|Animals|*Collaborative Cross Mice|*Bone|*Study, Genetic Association|Genome Mapping|Osteoporosis|Bone Density|Quantitative Trait Loci|Femur|Chromosomes, Mammalian|Haplotype|Phenotype|Single Nucleotide Polymorphisms 19 SLFN5 26623250 Results Immunol 2015 PMC4625362 10.1016/j.rinim.2015.10.001 17 14 1 77 Humans|Mice|Animals|*Monocytes|*T Cells|Lymphocyte Activation|Cell Differentiation|Cell Cycle Proteins|Signal Transduction|Interferon|Cell Line|Immunity, Innate|Upregulation|Dendritic Cells 18 SLFN5 26377798 Am. J. Physiol. Renal Physiol. 2015 10.1152/ajprenal.00525.2014 1 0 0 77 Animals|*Zebrafish|Zebrafish Proteins|Podocytes|*Proteinuria|Kidney Glomerulus|Glomerular Filtration Barrier|Morpholinos|Gene Knockdown Techniques|Larvae|Tmem234 protein, zebrafish|Membrane Proteins 18 SLFN5 26012550 Mol. Cell. Biol. 2015 PMC4524119 10.1128/MCB.00019-15 17 0 1 77 Humans|*Carcinoma, Renal Cell|Kidney Neoplasms|*Cell Motility|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Cell Cycle Proteins|Interferon 18 SNORD48 26078486 Dis. Markers 2015 PMC4452852 10.1155/2015/973597 10 0 0 0 Humans|Male|*miRNA|*Prostate Cancer|Prostate-Specific Antigen|Benign Prostatic Hyperplasia|Digital Rectal Examination|Biomarkers, Tumor 18 SNORD48 25750034 Tumour Biol. 2015 10.1007/s13277-015-3278-5 1 0 0 0 Humans|Male|*miRNA|Messenger RNA|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Prostatic Neoplasms|Cell Line, Tumor 18 SPATA7 26147992 PLoS ONE 2015 PMC4493089 10.1371/journal.pone.0131679 12 0 1 20 Child|Humans|Young Adult|*Leber Congenital Amaurosis|*Retinitis Pigmentosa|*Homozygote|Genotype|DNA Mutational Analysis|Pedigree|Phenotype|Mutations|Retinal Degeneration|Eye Proteins|Electroretinography|MERTK|Gene Chip|Polymorphism, Single Nucleotide|Chromosome Mapping|Retina|Mutation, Nonsense|SPATA7 protein, human 33 SPATA7 25965394 Gene Ther. 2015 PMC5026120 10.1038/gt.2015.42 8 6 0 20 Humans|Mice|Animals|*Leber Congenital Amaurosis|*Knockout Mouse|*Retinitis Pigmentosa|*Gene Therapy|Adeno-Associated Virus|Photoreceptors, Cone|Retinal Rod Photoreceptor Cells|Genetic Vectors|Retinal Degeneration|Retina|Disease Models, Animal|SPATA7 protein, human|DNA-Binding Proteins|SPATA7 protein, mouse 33 SPATA7 25814828 Mol. Vis. 2015 PMC4360169 5 1 0 20 Humans|Adolescent|*Arabs|*Islam|*Homozygote|Retinitis Pigmentosa|Genes, Recessive|Pedigree|DNA Mutational Analysis|Eye Proteins|Base Sequence|Introns|Mutation|Electroretinography|Polymorphism, Single Nucleotide|SPATA7 protein, human|DNA-Binding Proteins 33 TESMIN 26296075 J. Hazard. Mater. 2015 10.1016/j.jhazmat.2015.08.010 9 0 0 39 Humans|Mice|Male|Animals|*Testis|titanium dioxide|Sperm Motility|Glycogen Synthase Kinase 3|*Titanium|Epididymis|Spermatogenesis|Sperm Number|Spermatozoa|*Gene Expression|Nanoparticles 18 TESMIN 25662276 Mol. Cell. Endocrinol. 2015 10.1016/j.mce.2015.01.027 5 0 0 39 NR3C2 protein, human|*Receptors, Mineralocorticoid|Aldosterone|Protein Binding|Ligands|Cortisol|Protein Conformation|Models, Molecular|Receptors, Steroid|Signal Transduction|tesmin|Metallothionein 18 wdr81 27390838 BMC Neurosci 2015 PMC4690267 10.1186/s12868-015-0229-4 0 2 1 101 Humans|Animals|Mice|*Zebrafish|Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 2|Dysequilibrium syndrome|*Intellectual Disability|*Cerebellar Ataxia|Zebrafish Proteins|*Muscle Hypotonia|Gene Expression Regulation, Developmental|In Situ Hybridization|*Psychomotor Disorders|*Perceptual Disorders|Amino Acid Sequence|WDR81 protein, human|Nerve Tissue Proteins 18 ADTRP 24573017 J. Atheroscler. Thromb. 2014 10.5551/jat.22640 16 1 3 78 Humans|*Coronary Artery Disease|Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cyclin-Dependent Kinase Inhibitor p15|Asian Continental Ancestry Group|Cyclin-Dependent Kinase Inhibitor p16|Case-Control Studies|Atherosclerosis|Risk Factors|PDGFD protein, human|Lymphokines|Platelet-Derived Growth Factor|TCF21 protein, human|Basic Helix-Loop-Helix Transcription Factors|UBE2Z protein, human|Ubiquitin-Conjugating Enzymes 18 ARL5B 25451939 J. Biol. Chem. 2014 PMC4294491 10.1074/jbc.M114.611053 7 1 1 224 18 ARL5B 24901509 PLoS Genet. 2014 PMC4046913 10.1371/journal.pgen.1004345 22 3 1 224 18 ATXN8OS 24703904 Cell Calcium 2014 10.1016/j.ceca.2014.03.002 3 5 0 39 *Down-Regulation|voltage-dependent calcium channel (P-Q type)|Calcium Channels, N-Type|Neurons|Calcium Channels, T-Type|*Calcium, Dietary|Synapses|Calcium Channels, L-Type|Hippocampus|Actin|Up-Regulation|Cells, Cultured|Synapsin I 70 CAMK1G 25057204 J. Neurosci. 2014 PMC4107395 10.1523/JNEUROSCI.2868-13.2014 0 6 3 35 Mice|Animals|*Leptin|*Hippocampus|Dendritic Spines|Neurons|Neurogenesis|Synapses|leptin receptor, human|Receptors, Leptin|CAMK1 protein, human|Calcium-Calmodulin-Dependent Protein Kinase Type 1|CaMKK|Signal Transduction|TRPC Cation Channels|Hypothalamus|Phosphorylation|Organ Culture Techniques 18 CAMK1G 24481079 Dev. Neurosci. 2014 10.1159/000357496 7 0 2 35 Animals|Mice|Female|Pregnancy|*Fetal Alcohol Spectrum Disorders|*Ethanol|*C57BL Mouse|Prenatal Exposure Delayed Effects|*Disease Models, Animal|Alcohol Drinking|Animals, Newborn|Epigenesis, Genetic|Brain|Gene Expression|*Acclimatization|Anxiety 18 CDHR5 24725409 Cell 2014 PMC3992856 10.1016/j.cell.2014.01.067 47 24 5 51 Humans|Mice|Animals|*Microvilli|Myosin|Enterocytes|Actins|*Intestines|Epithelial Cells|Carrier Proteins 19 CNTNAP5 24718909 Clin. Chem. 2014 10.1373/clinchem.2013.213611 19 0 4 24 Humans|*Neoplastic Cells, Circulating|*Prognosis|*Melanoma|Skin Neoplasms|*Cell Count|Biomarkers, Tumor|*Genomics|*Neoplasms, Second Primary 18 CNTNAP5 24387768 BMC Med. Genet. 2014 PMC3901032 10.1186/1471-2350-15-2 38 1 5 24 *Genome-Wide Association Study|*Bipolar Disorder|Canada|United Kingdom|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|CSMD1 protein, human|*Membrane Proteins|Nerve Tissue Proteins|Genotype|Nuclear Proteins|Cytoskeletal Proteins 18 CPXM2 24685769 Fetal. Diagn. Ther. 2014 10.1159/000360535 13 0 0 18 Infant, Newborn|Humans|Female|Pregnancy|*Fetal Growth Retardation|*Fetal Macrosomia|*Placenta|Fetal Growth|Insulin-Like Growth Factor II|*Infant, Small for Gestational Age|RNA, Messenger|Gene Expression|*Weight Gain 18 DNAJB2 25274842 Neurology 2014 10.1212/WNL.0000000000000966 14 0 3 97 Humans|Hereditary Motor and Sensory Neuropathies|Charcot-Marie-Tooth Disease|Mutations|Phenotype 32 GALK2 25535366 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC4291641 10.1073/pnas.1422165112 53 0 8 63 Humans|Female|Mice|Animals|*Nuclear Proteins|*Carcinoma, Ovarian Epithelial|*Transcription Factors|*Ovarian Cancer|Proto-Oncogene Proteins c-myc|Cell Cycle Proteins|Azepines|Cell Proliferation|Cell Line, Tumor|Apoptosis|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|shRNA|MTOR protein, human|TOR Serine-Threonine Kinases|Genes, myc|Cystadenocarcinoma, Serous|Triazoles 18 GALK2 26290712 J Anim Sci Technol 2014 PMC4540274 10.1186/2055-0391-56-23 2 1 0 63 Swine|Animals|Republic of Korea|Breeding|Genome|Selection, Genetic|Genomics|Genotype|Single Nucleotide Polymorphisms|Phenotype|High-Throughput Nucleotide Sequencing|Oligonucleotide Array Sequence Analysis 18 JPH1 25283457 Clin Plast Surg 2014 10.1016/j.cps.2014.06.007 1 0 0 121 Humans|Weight Loss|Abdominoplasty|Lipectomy|Dermatologic Surgical Procedures|Cosmetic Techniques|Obesity|Back|Torso|Plastic Surgery|Adiposity 18 JPH1 25168384 Hum. Mol. Genet. 2014 10.1093/hmg/ddu440 12 3 1 121 Humans|Animals|Charcot-Marie-Tooth disease, Type 2K|*Charcot-Marie-Tooth Disease|junctophilin|*Genes, Modifier|*Membrane Proteins|Nerve Tissue Proteins|Mitochondria|Endoplasmic Reticulum|Phenotypes|Mutation|Axons|Homeostasis 18 JPH1 25100314 J R Soc Interface 2014 PMC4233733 10.1098/rsif.2014.0570 10 0 1 121 Rats|Animals|*Calcium|Sarcoplasmic Reticulum|Calsequestrin|Ryanodine Receptors|*Muscle, Skeletal|Muscle Fibers, Slow-Twitch|Muscle Fibers, Fast-Twitch|Muscle Fibers, Skeletal|*Fasciculation|Calcium-Binding Proteins|*Calcium, Dietary|junctophilin|Membrane Proteins|*Muscular Diseases 18 JPH1 24954085 J. Neurol. Sci. 2014 PMC4143440 10.1016/j.jns.2014.06.006 7 1 0 121 Humans|*Plaque, Atherosclerotic|*Hispanics|Carotid Artery Diseases|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|*Smoking|Gene Frequency|*Tobacco Smoking|Phenotype|Risk Factors|*Plaque, Amyloid 18 KLHL40 25428687 Neurology 2014 PMC4336094 10.1212/WNL.0000000000001110 19 0 1 71 Child|Humans|Myopathies, Nemaline|Myopathy, Central Core|Myopathies, Structural, Congenital|Muscle Proteins|Muscle, Skeletal|*Cohort Studies|Phenotype|Mutation|Genotypes 19 KLHL40 25110572 Skelet Muscle 2014 PMC4126377 10.1186/2044-5040-4-15 12 13 0 71 nebulin|*Tropomyosin|*Actins|*Muscle Proteins|Nemaline Myopathy|Muscle Disorder|Sarcomeres|Actin Cytoskeleton|Muscle, Skeletal|Mutations|Troponin T 19 KLHL40 24960163 J. Clin. Invest. 2014 PMC4109545 10.1172/JCI74994 38 1 3 71 Humans|Mice|Animals|*Myopathies, Nemaline|*Sarcomeres|nebulin|Muscle Proteins|Muscle, Skeletal|Muscle Contraction|Muscle Weakness|*Actin Cytoskeleton|Phenotype|KLHL40 protein, human 19 MESP2 25343988 Hum. Mol. Genet. 2014 10.1093/hmg/ddu534 6 0 0 93 Humans|Male|Mice|Animals|Somite|Basic Helix-Loop-Helix Transcription Factors|*Mutations|Repressor Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Mesoderm|*Heterozygote|Embryogenesis|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Signal Transduction|Glycosyltransferases|Lfng protein, mouse 95 MMRN2 25294124 Neurogenetics 2014 10.1007/s10048-014-0425-x 5 0 1 55 Humans|*Exome|*Parkinson Disease|SNPs|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Gene Frequency|Mutations|Whole Exome Sequencing|Odds Ratio|Risk Factors|Sardinia|Portugal|Spain|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins 18 NLRP9 24901306 PLoS ONE 2014 PMC4047072 10.1371/journal.pone.0098899 23 18 3 79 Humans|*Helicobacter Infections|*Stomach Neoplasms|*Helicobacter pylori|*Case-Control Studies|*Stomach|Genetic Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Toll-Like Receptor 4|Genotype|*Signal Transduction|NOD-like Receptors 18 PHF3 25029256 PLoS ONE 2014 PMC4100922 10.1371/journal.pone.0102464 6 26 0 73 Humans|transcription factor S-II|*Transcription Factor|Saccharomyces cerevisiae|Transcriptional Elongation Factors|RNA Polymerase II|Saccharomyces cerevisiae Proteins|*DNA-Binding Proteins|*Genome|Chromatin|histone H3 trimethyl Lys4|Histone H3|Transcription, Genetic|Gene Expression Regulation, Fungal|Promoter Regions, Genetic|Chromatin Immunoprecipitation|*Genomics|Bye1 protein, S cerevisiae 19 PHF3 24961364 Am J Addict 2014 PMC4111256 10.1111/j.1521-0391.2013.12115.x 6 0 0 73 Humans|Genome-Wide Association Study|*Alcoholism|PTP4A1 protein, human|*Membrane Proteins|*Cell Cycle Proteins|*Protein Tyrosine Phosphatases|European Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|African Americans|Case-Control Studies|EYS protein, human|Eye Proteins 19 PHF3 24507961 Theriogenology 2014 10.1016/j.theriogenology.2014.01.002 1 0 0 73 Animals|*Goat|Parthenogenesis|Embryo Development|Blastocyst|Fertilization in Vitro|*Gene Expression|Morula|Oocytes|Fertilization|*Microarray Analysis|Gene Expression Regulation, Developmental|Gene Expression Profiling|Diploid 19 RASEF 25281934 Dev. Biol. 2014 10.1016/j.ydbio.2014.09.028 7 0 0 44 Animals|Female|*Caenorhabditis elegans|*Cues|Caenorhabditis elegans Proteins|Vulva|*Organogenesis|Transcription Factors|Gene Expression Regulation, Developmental|Animals, Genetically Modified|Cell Lineage|Uterus|Cell Movement|Signal Transduction|Mutation|FOS-1 protein, C elegans|Proto-Oncogene Proteins c-fos 18 RASEF 25183398 BMC Genomics 2014 PMC4168119 10.1186/1471-2164-15-754 6 4 1 44 Animals|Male|Female|*Cyprinodontiformes|*Transcriptome Profiling|Pigmentation|Transcriptome|Phenotype|Genetic Linkage|Receptor, Melanocortin, Type 1|Aging 18 RASEF 24703243 Pigment Cell Melanoma Res 2014 10.1111/pcmr.12248 9 1 1 44 *Proto-Oncogene Proteins B-raf|*RNA Interference|Melanoma, Cutaneous Malignant|*Melanoma|Skin Neoplasms|Nevi|Melanocytes|PTEN protein, human|PTEN Phosphohydrolase|Melanocytic Nevi|Cellular Senescence|Oncogenes|Tumor Suppressor Protein p53|Genes, Tumor Suppressor|Cell Line, Tumor|Cell Proliferation|Upregulation 18 RIPPLY2 25343988 Hum. Mol. Genet. 2014 10.1093/hmg/ddu534 6 0 0 35 Humans|Male|Mice|Animals|Somite|Basic Helix-Loop-Helix Transcription Factors|*Mutations|Repressor Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Mesoderm|*Heterozygote|Embryogenesis|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Signal Transduction|Glycosyltransferases|Lfng protein, mouse 31 RIPPLY2 25259583 PLoS ONE 2014 PMC4178057 10.1371/journal.pone.0107928 6 16 0 35 Mice|Animals|*Somites|Zebrafish|Zebrafish Proteins|Body Patterning|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|Embryonic Development|Repressor Proteins|mRNA 31 SGCZ 25083881 PLoS ONE 2014 PMC4118997 10.1371/journal.pone.0103968 1 0 0 21 Female|Humans|*DNA Copy Number Variations|Genome-Wide Association Study|*Endometriosis|SNPs|Genetic Predisposition to Disease|Genotype|Genome, Human|Case-Control Studies|Chromosomes, Human|Algorithms 19 SGCZ 24792710 Neuroscience 2014 10.1016/j.neuroscience.2014.04.034 2 0 1 21 *Myoclonus|Myoclonic dystonia|*Dystonic Disorders|epsilon-Sarcoglycan|*Mutations|Phenotype|Exons|Dystonia 19 SGCZ 24735523 Mol Cytogenet 2014 PMC4005464 10.1186/1755-8166-7-25 2 3 0 21 Child|Humans|Female|*Intellectual Disability|Chromosome Deletion|Chromosome Banding|Comparative Genomic Hybridization|*Speech Delay|Abnormalities, Multiple|Developmental Disabilities|In Situ Hybridization, Fluorescence|Phenotype|Gene Chip|*Chromosomes, Human|*Chromosome Structures|N33 protein, human|Membrane Proteins|Tumor Suppressor Proteins|MIRN383 microRNA, human|MicroRNAs 19 SLC35F2 25064833 Nat. Chem. Biol. 2014 PMC4913867 10.1038/nchembio.1590 45 3 10 61 Humans|YM 155|*Naphthoquinones|*Imidazoles|*DNA Damage|Inhibitor of Apoptosis Proteins|Survivin|Cell Line, Tumor|Antineoplastic Agents|Cell Survival|Apoptosis|Cell Proliferation|SLC35F2 protein, human|Membrane Transport Proteins 18 SNORD48 25420464 Int. J. Oncol. 2014 10.3892/ijo.2014.2775 12 0 0 0 Humans|Neoplasm Recurrence, Local|*Colorectal Cancer|*Adenocarcinoma|Prognosis|miRNAs|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Upregulation|Real-Time Polymerase Chain Reaction|Lymphatic Metastasis|*Relapse|MIRN224 microRNA, human 18 SNORD48 25203915 Forensic Sci Int Genet 2014 10.1016/j.fsigen.2014.08.005 8 0 1 0 *RNA, Micro|*Real-Time Polymerase Chain Reaction|Forensic Genetics|Messenger RNA|Gene Expression Profiling|Body Fluids|Standardization|Saliva|Skin|Semen 18 SNORD48 24535468 Endocrine 2014 10.1007/s12020-014-0202-5 7 0 1 0 *miRNA|Gastro-enteropancreatic neuroendocrine tumor|*Neuroendocrine Tumors|Pancreatic Neoplasms|Intestinal Neoplasms|Ileal Neoplasms|Stomach Neoplasms|Biomarkers, Tumor|*Pancreas|Gene Expression Profiling|*Ileum|Real Time PCR|Downregulation 18 SPATA7 25465359 Anim. Reprod. Sci. 2014 10.1016/j.anireprosci.2014.10.022 7 0 2 20 Humans|Cattle|Male|Animals|*Genome-Wide Association Study|*Semen|*Semen Analysis|*Sperm Count|Sperm Motility|Sperm|Genotype|SNPs|Artificial Insemination|Genetic Markers|Genome|DCP1A protein, human|Endoribonucleases|Trans-Activators|SPATA7 protein, human|DNA-Binding Proteins|SFMBT1 protein, human|Repressor Proteins 33 SPATA7 25398945 Hum. Mol. Genet. 2014 PMC4351378 10.1093/hmg/ddu573 25 1 2 20 Humans|Child|Mice|Adolescent|Animals|*Retina|Rod Photoreceptors|Retinitis Pigmentosa|Photoreceptor Connecting Cilium|*Ciliopathy|Rhodopsin|Leber Congenital Amaurosis|Retinal Degeneration|Eye Proteins|*Protein Transport|DNA-Binding Proteins|Mice, Knockout|Cilia|*Synapsins|SPATA7 protein, human|RPGRIP1 protein, human|Proteins|SPATA7 protein, mouse 33 SPATA7 25133751 PLoS ONE 2014 PMC4136783 10.1371/journal.pone.0104281 4 1 0 20 Humans|*High-Throughput Nucleotide Sequencing|*Retinal Dystrophy|*Mutation|DNA Mutational Analysis|Pedigree|*DNA|Eye Proteins|Genetic Screening|Phenotype|Genetic Variation 33 TESMIN 24907116 FASEB J. 2014 10.1096/fj.13-242479 4 0 0 39 Humans|Chlorocebus aethiops|Animals|NR3C2 protein, human|*Receptors, Mineralocorticoid|Aldosterone|*Protein Binding|*Mineralocorticoids|Cortisol|Ligands|Protein Structure, Tertiary|Yeast Two-Hybrid Assay|Signal Transduction|COS Cells 18 TESMIN 24565835 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.02.055 6 5 0 39 Male|Humans|Rats|Animals|*Testis|tesmin|*Metallothionein|*Zinc|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Cyclophosphamide|Sperm Count|Sperm|Epididymis|Sperm Motility|Testosterone|Oxidative Stress|Lipid Peroxidation|Antineoplastic Agents, Alkylating|Spermiogenesis|Malondialdehyde|Sperm Head 18 wdr81 25193853 Oncotarget 2014 PMC4253428 10.18632/oncotarget.2374 10 5 2 101 Humans|*Cell Surface Proteins|*Epitopes|*Tumors, Colorectal|*DNA Mutational Analysis|*Mutations|HCT116 Cells|HT29 Cells|axl receptor tyrosine kinase|Proto-Oncogene Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Caco-2 Cells|Receptor Protein-Tyrosine Kinases|FGFRL1 protein, human|Receptor, Fibroblast Growth Factor, Type 5|Sema4c protein, human|Semaphorins 18 ADTRP 23337689 Clin. Biochem. 2013 10.1016/j.clinbiochem.2013.01.004 12 1 2 78 Humans|*Polymorphism, Single Nucleotide|*Coronary Artery Disease|Genome-Wide Association Study|*Ethnic Groups|Chinese|Genetic Predisposition to Disease|Genetic Association Studies|*Chromosome 1|Gene Frequency|Case-Control Studies|Genotype|*Chromosome Structures|Lipids|Malaysia|ADTRP protein, human|Membrane Proteins 18 ATXN8OS 24040107 PLoS ONE 2013 PMC3770663 10.1371/journal.pone.0073885 2 2 0 39 Humans|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Spinocerebellar ataxia 8|Spinocerebellar Degenerations|Nerve Tissue Proteins|Open Reading Frames|RNA, Long Noncoding|*Polyribosomes 70 ATXN8OS 23791884 Cancer Lett. 2013 10.1016/j.canlet.2013.06.013 360 0 42 39 Humans|*RNA, Long Non-Coding|Cancers 70 ATXN8OS 23603541 Rinsho Shinkeigaku 2013 10.5692/clinicalneurol.53.278 0 0 0 39 Male|Humans|Adult|Spinocerebellar Ataxias|*Parkinsonism, Juvenile|Trinucleotide Repeats|Trinucleotide Repeat Expansion|Tremor|Pedigree|RNA, Untranslated|Nerve Tissue Proteins|RNA, Long Noncoding|Alleles 70 CAMK1G 24040449 Int J Clin Exp Pathol 2013 PMC3759491 4 3 0 35 Rats|Animals|*Endothelial Cells|Neovascularization, Physiologic|Intercellular Signaling Peptides and Proteins|Up-Regulation|Cell Proliferation|Signal Transduction|Cells, Cultured|Nerve Growth Factor|RNA, Messenger|Neovascularization, Pathologic|Downregulation|Mitogens 18 CAMK1G 23624525 Nat. Genet. 2013 10.1038/ng.2627 18 0 1 35 Humans|*Genome-Wide Association Study|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Asian Continental Ancestry Group|SNPs|Genetic Predisposition to Disease|Genetic Loci|Odds Ratio|Cohort Studies 18 CDHR5 23904255 Histol. Histopathol. 2013 10.14670/HH-29.11 2 1 0 51 Cadherins|*Carcinogenesis|Colorectal Cancer|Catenins|beta Catenin|Signal Transduction|Up-Regulation|Cell Adhesion|Downregulation|Cell Movement|Cell Line, Tumor|Transcriptional Activation 19 CHURC1 23443939 Dev. Dyn. 2013 PMC3690002 10.1002/dvdy.23958 4 11 0 49 Animals|*Zebrafish|Zebrafish Proteins|Nodal Protein|Embryo, Nonmammalian|*Cell Migration|Body Patterning|Mesoderm|Signal Transduction|Gene Expression Regulation, Developmental|Transforming Growth Factor beta|Trans-Activators|Zinc Finger|*Gene Expression|Genes, Developmental 18 DIRAS1 23436800 Cancer Res. 2013 10.1158/0008-5472.CAN-12-2663 23 1 3 155 *Esophageal Squamous Cell Carcinoma|*Down-Regulation|*Esophageal Neoplasms|*Genes, Tumor Suppressor|Carcinoma, Squamous Cell|Promoter Regions, Genetic|DNA Methylation|Lymphatic Metastasis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Prognosis|Neoplasm Staging|Cell Motility|Tumor Suppressor Proteins|Gene Silencing|Cell Line, Tumor|Signal Transduction 18 DNAJB2 24023695 PLoS ONE 2013 PMC3758296 10.1371/journal.pone.0073944 18 24 3 97 Mice|Humans|Animals|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Superoxide Dismutase-1|*Neuroprotection|*Superoxide Dismutase|Motor Neurons|Mice, Transgenic|Spinal Cord|*Molecular Chaperone|*Disease Models, Animal|Cell Survival|Disease Progression|Ubiquitin|Brainstem|DNAJB2 protein, human|HSP40 Heat-Shock Proteins|SOD1 protein, human|DNAJB2 protein, mouse 32 DNAJB2 23607970 Biol. Psychiatry 2013 PMC3740016 10.1016/j.biopsych.2013.02.027 42 25 1 97 *Heat Shock Protein 70|*tau Proteins|Tauopathies|Alzheimer Disease|HSC70 Heat-Shock Proteins|*Synaptic Plasticity|Hippocampus 32 GALK2 23967260 PLoS ONE 2013 PMC3743790 10.1371/journal.pone.0071897 10 7 2 63 Humans|*Induced Pluripotent Stem Cells|*Glucose|*Arginine|*Hepatocytes|Cell Differentiation|Cell Line|Cell Culture Techniques|Culture Media|Oncostatin M|Galactokinase|Galactose 18 JPH1 23465861 Am. J. Pathol. 2013 10.1016/j.ajpath.2013.01.020 10 0 2 121 Mice|Animals|*Mice, Inbred mdx|Motor Activity|*Muscle Contraction|Muscular Dystrophy, Animal|Muscle, Skeletal|Duchenne Muscular Dystrophy|Dystrophin|Muscle Fibers, Skeletal|Mice, Inbred C57BL|Muscle Weakness|Physical Conditioning, Animal|Disease Models, Animal|*Cardiovascular Physiological Phenomena|*Locomotion 18 KLHL40 23746549 Am. J. Hum. Genet. 2013 PMC3710748 10.1016/j.ajhg.2013.05.004 57 1 3 71 Humans|*Myopathies, Nemaline|Muscle Proteins|*Mutations|Muscle, Skeletal|KLHL40 protein, human 19 LMLN 24321998 Eur J Cardiothorac Surg 2013 10.1093/ejcts/ezt550 5 0 0 98 *Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Prognosis|Pneumonectomy|Neoplasm Staging|Lymphatic Metastasis|Lymph Nodes|Adenocarcinoma|Lymph Node Excision|Survival Rate|Retrospective Studies 18 LMLN 23422038 Exp. Cell Res. 2013 PMC3632754 10.1016/j.yexcr.2013.02.005 2 6 0 98 Animals|*Zebrafish|Zebrafish Proteins|Embryo, Nonmammalian|*Cell Migration|Animals, Genetically Modified|Gene Expression Regulation, Developmental|Drosophila Proteins|Amino Acid Sequence|Conserved Sequence|Sequence Homology, Amino Acid|Metalloproteases|Neovascularization, Physiologic|Metalloendopeptidases|Protein Transport 18 MIR193A 24287458 Mod. Pathol. 2013 10.1038/modpathol.2013.213 5 0 2 1 SMARCB1 protein, human|*SMARCB1 Protein|*Rhabdoid Tumor|*Epithelioid Sarcoma|DNA-Binding Proteins|Transcription Factors|*Downregulation|Soft Tissue Neoplasms|Chromosomal Proteins, Non-Histone|Gene Expression Regulation, Neoplastic|MicroRNAs|Immunohistochemistry|Biomarkers, Tumor|RNA, Messenger|In Situ Hybridization, Fluorescence 18 MIR193A 23588298 Int. J. Oncol. 2013 PMC3699598 10.3892/ijo.2013.1896 36 2 9 1 Humans|Female|*Carcinoma, Ovarian Epithelial|*RNA, Micro|*Ovarian Cancer|Cell Line, Tumor|*Gain of Function Mutation|*Apoptosis|Neoplasms, Glandular and Epithelial|Cell Proliferation|CCND1 protein, human|Cyclin D1|Gene Expression Regulation, Neoplastic|MCL1 protein, human|Myeloid Cell Leukemia Sequence 1 Protein|Cell Movement|Down-Regulation|CASP3 protein, human|Caspase 3|3' Untranslated Regions 18 MMRN2 23979707 Mol. Cell Proteomics 2013 PMC3861710 10.1074/mcp.M113.031344 25 0 4 55 Humans|*Tumor Markers|*Proteomics|matrigel|Laminin|Proteoglycans|Pathological Angiogenesis|Collagen|Membrane Glycoproteins|*Cell Differentiation|Cell Movement|Human Umbilical Vein Endothelial Cells|Lectins, C-Type|Vascular Endothelial Growth Factor A|Antigens, Surface|Cell Proliferation|Signal Transduction|*Morphogenesis|Extracellular Matrix 18 MTCH1 24205158 PLoS ONE 2013 PMC3813515 10.1371/journal.pone.0078205 2 0 0 78 *Biological Assay|Uncertainty 18 MTCH1 24035008 J. Neuroimmunol. 2013 10.1016/j.jneuroim.2013.08.007 3 2 0 78 18 MTCH1 23874806 PLoS ONE 2013 PMC3712916 10.1371/journal.pone.0068907 13 22 1 78 Female|Humans|*Progesterone|*Mifepristone|*Tamoxifen|*Transcriptome|*Endometrial Cancer|*Estrogens|Receptors, Progesterone|Estradiol|*Sequencing, RNA|*Whole Exome Sequencing|*Base Sequence|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Steroids|RNA 18 NSUN5 23913415 Nucleic Acids Res. 2013 PMC3799443 10.1093/nar/gkt679 0 5 6 43 Humans|*Saccharomyces cerevisiae|RNA, ribosomal, 25S|*RNA, Ribosomal|Saccharomyces cerevisiae Proteins|Methyltransferases|*Yeast, Dried|Ribosome|Methylation|Nuclear Proteins|Cardiomyopathy, Familial Restrictive, 1|*Cardiomyopathy, Restrictive|NOP2 protein, S cerevisiae 18 NSUN5 23816522 Gene Expr. Patterns 2013 10.1016/j.gep.2013.06.003 14 0 3 43 Humans|Male|Female|Pregnancy|Animals|Mice|*RNA|*Methyltransferases|Methylation|*Embryo Development|In Situ Hybridization|RNA, Messenger|Cell Differentiation|Male Sterility|NSUN2 protein, human|NSUN6 protein, human|tRNA Methyltransferases|Nsun7 protein, mouse 18 PHF3 24003114 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3780847 10.1073/pnas.1311010110 16 8 1 73 Humans|*RNA Polymerase II|transcription factor S-II|Transcriptional Elongation Factors|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Gene Expression Regulation, Fungal|Chromatin|Transcription, Genetic|Histones|Nuclear Protein|Protein Structure, Tertiary|Transcription Factors|Peptidylprolyl Isomerase|*Cell Nucleus|Bye1 protein, S cerevisiae 19 PHF3 23831028 Cell Rep 2013 PMC3967714 10.1016/j.celrep.2013.06.014 20 24 2 73 *DNA-Binding Proteins|histone H3 trimethyl Lys4|Histone|*Cell Differentiation|Transcription Factors|Chromatin|Binding Site|Embryonic Stem Cells|Methylation|Amino Acid Sequence|Protein Structure, Tertiary|Protein Binding 19 RASEF 23686708 Mol. Cancer Res. 2013 10.1158/1541-7786.MCR-12-0685-T 6 4 0 44 *Lung Cancers|Non-Small-Cell Lung Carcinomas|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Cell Line, Tumor|Prognosis|Cell Proliferation|Lung|RNA, Small Interfering|Extracellular Signal-Regulated MAP Kinases|Tissue Array Analysis|Biomarkers 18 RIPPLY2 23727513 Dev. Biol. 2013 10.1016/j.ydbio.2013.05.020 6 1 0 35 Mice|Animals|*Somites|*Embryo, Mammalian|Body Patterning|*Intervertebral Disk|Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Cell Differentiation 31 SGCZ 24189654 J Mol Diagn 2013 PMC3873496 10.1016/j.jmoldx.2013.08.004 96 0 13 21 Humans|*DNA Copy Number Variations|Protein-Tyrosine Kinases|Proto-Oncogene Proteins|High-Throughput Nucleotide Sequencing|Sequence Analysis, DNA|*Rearrangements, Gene|Mutations|Paraffin Embedding|Cancer|*Mutation, Activation|*Chromosome Aberrations|Number, Gene Copy 19 SLC35F2 23879892 Cancer Cell Int. 2013 PMC3724707 10.1186/1475-2867-13-73 2 3 0 61 Humans|*Lung Cancer|RNA Interference|RNA, Small Interfering|Cell Proliferation|Cell Movement|Cell Line, Tumor|Transfection|Cell Cycle|RNA, Messenger|Tumor Burden|Downregulation|SLC35F2 protein, human|Membrane Transport Proteins 18 SLFN5 24089532 J. Biol. Chem. 2013 PMC3829150 10.1074/jbc.M113.460741 12 0 2 77 Mice|Animals|*Carcinoma, Renal Cell|Melanoma, Cutaneous Malignant|*Malignant Melanoma|*Skin Neoplasms|Kidney Neoplasms|Cell Proliferation|Cell Cycle Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Interferon-alpha|Up-Regulation|Signal Transduction 18 SNORD48 23703249 Br. J. Cancer 2013 PMC3694240 10.1038/bjc.2013.250 31 6 6 0 Humans|Male|*Disease-Free Survival|Neoplasm Recurrence, Local|*Prostate Cancer|Prostate-Specific Antigen|Prostatectomy|Neoplasm Grading|*Genes, Tumor Suppressor|Prostatic Hyperplasia|MicroRNAs|Gene Expression Regulation, Neoplastic|Neoplasm Staging|Biomarkers, Tumor|Lymphatic Metastasis|Disease Progression|ROC Curve|MIRN145 microRNA, human 18 TESMIN 24055800 Toxicology 2013 10.1016/j.tox.2013.09.003 8 6 1 39 Animals|Male|tributyltin|*Sertoli Cells|*Testis|*Coculture Techniques|*Trialkyltin Compounds|*Cell Death|*Redox|NFE2L2 protein, human|NF-E2-Related Factor 2|Reactive Oxygen Species|Membrane Potential, Mitochondrial|Cell Survival|Apoptosis|Oxidative Stress|Blood-Testis Barrier|Glutathione|Endocrine Disruptors|Germ Cells 18 wdr81 23595742 J. Neurosci. 2013 PMC6618862 10.1523/JNEUROSCI.2394-12.2013 12 0 3 101 Humans|Mice|Animals|Purkinje Cells|Cerebellum|Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 2|Cerebellar Ataxia|Phenotype|N-Ethyl-N-nitrosourea|Calbindins|*Cell Survival|Nerve Tissue Proteins|S100 Calcium Binding Protein G|Mutation|Neurons|Mental Retardation|Homozygote|*Photoreceptor Cell|WDR81 protein, human 18 ARL5B 22245584 Exp. Cell Res. 2012 10.1016/j.yexcr.2011.12.023 12 1 0 224 18 ATXN8OS 22670601 Recent Pat DNA Gene Seq 2012 10.2174/187221512801327442 3 0 0 39 Adult|Humans|*Spinocerebellar Ataxias|Ataxins|Ataxin-1|Ataxin-7|Ataxin-3|Trinucleotide Repeat Expansion|polyglutamine|Peptides|Nuclear Proteins|Nerve Tissue Proteins|Gene Frequency|Repressor Proteins|Mutations|Calcium Channels 70 ATXN8OS 22581592 Neurol. Neurochir. Pol. 2012 10.5114/ninp.2012.28253 1 0 0 39 Humans|*Myotonic Dystrophy|Spinocerebellar ataxia 8|*Epilepsy, Progressive Myoclonic Type 1|*Spinocerebellar Degenerations|Myotonin-Protein Kinase|Trinucleotide Repeat Expansion|Triplet Repeat|Polymerase Chain Reaction|DNA|Mutations|Spinocerebellar Ataxias 70 CAMK1G 23074277 Blood 2012 PMC4507036 10.1182/blood-2012-06-434894 0 3 1 35 Humans|berbamine|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|*Benzylisoquinolines|Imatinib Mesylate|Benzamides|Pyrimidines|Piperazines|Protein Kinase Inhibitors|K562 Cells|Apoptosis|Drug Resistance, Neoplasm|Signal Transduction|Cell Proliferation|Neoplastic Stem Cells|Phosphorylation 18 CPXM2 22383091 J. Assoc. Res. Otolaryngol. 2012 PMC3346896 10.1007/s10162-012-0316-5 1 0 0 18 Mice|Humans|Animals|Cochlea|*Insertion Mutation|Vestibule, Labyrinth|Stria Vascularis|Transgenic Mouse|Vestibular Diseases|Phenotype|Hearing Loss|Deafness|Semicircular Canals|Homozygote|Gene Expression Regulation, Developmental 18 DNAJB2 22522442 Ann. Neurol. 2012 10.1002/ana.22684 22 2 4 97 *Molecular Chaperones|*Mutation|HSP40 Heat-Shock Proteins|Pedigree|Genetic Predisposition to Disease|Chromosome Mapping|Morocco 32 DNAJB2 22396390 Brain 2012 PMC3326252 10.1093/brain/aws022 33 25 3 97 Animals|Mice|*Protein Aggregates|*Molecular Weight|HTT protein, human|Huntingtin Protein|*Molecular Chaperones|Huntington Disease|Nerve Tissue Proteins|HSP40 Heat-Shock Proteins|Mice, Transgenic|Nuclear Proteins|Neurons|HSP70 Heat-Shock Proteins|Disease Models, Animal|polyglutamine|Peptides|Brain-Derived Neurotrophic Factor|Transfection|Neurodegenerative Diseases 32 GALK2 22761715 PLoS ONE 2012 PMC3384611 10.1371/journal.pone.0038950 26 41 1 63 Humans|Male|*RNA Interference|AR protein, human|Androgen Receptor|*Prostate|Androgens|Castration|Cell Proliferation|Prostatic Neoplasms, Castration-Resistant|shRNA|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Line, Tumor|Apoptosis|RNA, Messenger|Cell Cycle|GALK2 protein, human|Galactokinase 18 GALK2 22318827 Yonsei Med. J. 2012 PMC3282964 10.3349/ymj.2012.53.2.377 2 3 1 63 Humans|histone H3 trimethyl Lys4|*Histones|*Lysine|*Glomerulonephritis, IGA|*Leukocytes, Mononuclear|*Chromatin Immunoprecipitation|CpG Islands|DNA Methylation|Epigenesis, Genetic|Oligonucleotide Array Sequence Analysis|*Leukocytes 18 gpr19 22912338 Mol. Cancer Res. 2012 10.1158/1541-7786.MCR-12-0139 9 1 3 4 Humans|*S Phase|*Lung Cancer|*M Phase|Cell Cycle|RNA Interference|mRNA|siRNA|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Binding Sites|Phosphorylation|Histone H3|Chromatin Immunoprecipitation|Cell Proliferation|Transfections|Cell Line, Tumor|Cyclin B1 18 MIR193A 22438885 PLoS ONE 2012 PMC3306368 10.1371/journal.pone.0032853 6 1 0 1 Humans|Male|*MicroRNAs|*XMRV Infection|Xenotropic murine leukemia virus-related virus|Chronic Fatigue Syndrome|RNA, Viral|Prostate Cancer|Cell Lines|Antibodies, Viral 18 MTCH1 23207240 Biochim. Biophys. Acta 2012 PMC4624219 10.1016/j.bbadis.2012.11.016 4 56 0 78 APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|*Apoptosis Regulatory Proteins|*Mitochondria|Caspases|Protein, Mitochondrial|bcl-2-Associated X Protein|Proto-Oncogene Proteins c-bcl-2|Apoptosis|Cytochrome c|Caspase 9|bcl-X Protein|Apoptosome|Caspase 3|Caspase Inhibitors|*B Cell Lymphoma|Intracellular Signaling Peptides and Proteins|Binding Protein 18 RIPPLY2 22892537 Eur. J. Hum. Genet. 2012 PMC3598331 10.1038/ejhg.2012.177 9 0 0 35 Humans|Mice|Animals|*Clubfoot|*DNA Copy Number Variations|Genetic Predisposition|Pedigree|Genes, Homeobox|*Gene Expression Regulation|Homeodomain Proteins|Transcription Factors|Musculoskeletal Abnormalities|*Organogenesis 31 SGCZ 22836685 Obesity (Silver Spring) 2012 PMC3484176 10.1038/oby.2012.162 8 0 3 21 Humans|*DNA Copy Number Variations|*African Americans|Genome-Wide Association Study|*Genetic Epidemiology|*Obesity|Single Nucleotide Polymorphisms|*Hypertension|Body Mass Index|Genetic Predisposition to Disease|*Phenotype|European Continental Ancestry Group 19 SGCZ 22593182 Mol. Endocrinol. 2012 PMC5417001 10.1210/me.2011-1341 31 7 5 21 Mice|Animals|Female|*Oestradiol|*Transcriptional Activation|NR5A1 protein, human|*Steroidogenic Factor 1|Granulosa Cells|miRNA|*Estrogens|Ovary|*Genes, Regulator|Cell Proliferation|Gene Expression Regulation|Transcription Factor|Promoter Regions, Genetic 19 SLFN5 22906252 Am. J. Surg. 2012 PMC4574865 10.1016/j.amjsurg.2012.07.004 11 10 1 77 Rats|Animals|Enterocytes|Cell Differentiation|Jejunum|Ileum|Intestinal Mucosa|Intestines|Cell Proliferation|RNA, Messenger|Microfilament Proteins|Schlafen 3 protein, rat|Proteins 18 SLFN5 22586265 Mol. Cell. Biol. 2012 PMC3416205 10.1128/MCB.00310-12 17 5 0 77 *Interferon|*Apoptosis Regulatory Proteins|p70 S6 Kinase|Eukaryotic Initiation Factor-4G|Eukaryotic Initiation Factor-4A|Phosphorylation|mRNA Translation|p90 Ribosomal S6 Kinase|*Antiviral Agents|TOR Serine-Threonine Kinases|Signal Transduction|RNA-Binding Proteins|Downregulation|Carrier Proteins|Cells, Cultured|Cyclin-Dependent Kinase Inhibitor p21|Apoptosis 18 SNORD48 22788411 Int. J. Urol. 2012 10.1111/j.1442-2042.2012.03082.x 31 0 5 0 Humans|Male|*Carcinoma, Renal Cell|*miRNA|*Urinary Bladder Neoplasms|*Prostate|Kidney Neoplasms|*Prostate Cancer|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Real-Time Polymerase Chain Reaction|*Rare Diseases 18 SNORD48 22674506 Am. J. Hematol. 2012 10.1002/ajh.23227 13 0 3 0 *Leukemia, Lymphocytic, Chronic, B-Cell|*Prognosis|*RNA|Pilot Projects|*Sequencing, Next-Generation|Immunoglobulin Heavy Chains|Sequencing, RNA|Gene Expression Profiling|RNA, Messenger|Mutations|Neoplasm Proteins|RNA Splicing|Biomarkers, Tumor|Exon|Transcriptomes 18 wdr81 23022100 Am. J. Hum. Genet. 2012 PMC3484648 10.1016/j.ajhg.2012.08.021 38 1 4 101 Humans|Animals|Mice|Genome-Wide Association Study|Linkage Disequilibrium|Genetic Loci|Asian Continental Ancestry Group|Alleles|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|European Continental Ancestry Group|ELL2 protein, human|Transcriptional Elongation Factors|SERPINF2 protein, human|alpha-2-Antiplasmin|FRMD5 protein, human|Tumor Suppressor Proteins|WDR81 protein, human|Nerve Tissue Proteins|WDR76 protein, human|Chromosomal Proteins, Non-Histone 18 wdr81 22973972 BMC Med. Genet. 2012 PMC3495048 10.1186/1471-2350-13-80 13 2 0 101 Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 3|Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 2|Dysequilibrium syndrome|*Cerebellar Ataxia|*Intellectual Disability|VLDL receptor|*Receptors, LDL|*Missense Mutation|*Muscle Hypotonia|*Psychomotor Disorders|*Syndrome|*Locomotion|*Perceptual Disorders|Homozygote|Pedigree|Base Sequence|Cerebellum|Mutations 18 wdr81 22686558 Ophthalmic Genet. 2012 10.3109/13816810.2012.689412 6 1 2 101 Humans|Dysequilibrium syndrome|Cerebellar Ataxia|*Locomotion|Cerebellum|Atrophy|Mental Retardation|Magnetic Resonance Imaging|Pedigree|*Neurology|*Ophthalmology 18 ADTRP 21868574 Blood 2011 PMC3204913 10.1182/blood-2011-05-355370 31 5 4 78 Humans|lipoprotein-associated coagulation inhibitor|*Endothelial Cells|*Lipoproteins|Factor VIIa|CAV1 protein, human|Caveolin 1|TYRP1 protein, human|*Membrane Glycoproteins|Thromboplastin|Caveolae|Cell Membrane|*Androgens|Membrane Microdomains|*Endothelium|ADTRP protein, human|Membrane Proteins 18 ARL5B 22172677 Dev. Cell 2011 PMC3240744 10.1016/j.devcel.2011.10.007 80 21 10 224 18 ARL5B 21742265 Structure 2011 10.1016/j.str.2011.04.007 5 0 1 224 18 ATXN8OS 22053702 Hiroshima J. Med. Sci. 2011 1 0 0 39 Humans|Spinocerebellar Ataxia 12|Spinocerebellar Ataxias|Spinocerebellar Ataxia 10|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Trinucleotide Repeat Expansion|Ataxins|Ataxin-7|*PCR|Trinucleotide Repeats|Ataxia, Friedreich|Tandem Repeats, Short|Nerve Tissue Proteins|Pedigree|DNA Repeat Expansion 70 CDHR5 22202456 Gastroenterology 2011 10.1053/j.gastro.2011.12.037 18 11 5 51 Humans|Mice|Animals|*Colon Cancer|*Colon|Isx protein, human|Homeodomain Proteins|Transcription Factor CDX2|beta Catenin|HT29 Cells|*Catenins|Transcription Factors|Wnt Signaling Pathway|Intestinal Epithelium|Cell Differentiation|Gene Expression Regulation, Neoplastic|Caco-2 Cells|Intestines|CDX2 protein, human|Cdx2 protein, mouse 19 CDHR5 21926187 Ann. Rheum. Dis. 2011 PMC3369428 10.1136/annrheumdis-2011-200275 14 2 2 51 Humans|*Sclerosis, Systemic|*Autoantibodies|IRF7 protein, human|*Interferon Regulatory Factor-7|Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Autoimmune Diseases|Genotype|European Continental Ancestry Group 19 CHURC1 21360829 Autism Res 2011 PMC3110642 10.1002/aur.186 12 0 0 49 Male|Humans|Adolescent|*Autistic Disorder|DNA Copy Number Variations|*Chromosome 2|Comparative Genomic Hybridization|*Spherocytosis, Hereditary|Chromosome Deletion|Intellectual Disability|Pedigree|Genetic Predisposition to Disease|Chromosomal Aberrations|Disabilities, Learning|Genotype|SPTBN1 protein, human|beta-Spectrin|MTHFD1 protein, human|Methylenetetrahydrofolate Dehydrogenase (NADP)|Minor Histocompatibility Antigens 18 CNTNAP5 21423737 PLoS ONE 2011 PMC3053356 10.1371/journal.pone.0016729 34 3 3 24 *Diabetes Mellitus, Type 2|*Pilot Projects|*Bariatric Surgery|*Obesity|Glycated Hemoglobin A|Obesity, Morbid|Blood Glucose|Body Mass Index|*Gene Expression 18 DIRAS1 21750579 Neuropsychopharmacology 2011 PMC3176568 10.1038/npp.2011.120 10 1 0 155 Adult|Humans|Child|*Attention Deficit Disorder with Hyperactivity|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Phenotype|Genetic Association Studies|*Comorbidity|Haplotype|Personality Disorders|Bipolar Disorder|Genotype|Promoter Regions, Genetic|Personality 18 DNAJB2 21625540 PLoS ONE 2011 PMC3098244 10.1371/journal.pone.0019763 10 40 1 97 Humans|*Ataxin-3|*Molecular Chaperones|Ubiquitin|polyglutamine|Peptides|HSP40 Heat-Shock Proteins|HSP70 Heat-Shock Proteins|Amino Acid Sequence|Nuclear Proteins|Nerve Tissue Proteins|Heat-Shock Proteins|Proteasome Endopeptidase Complex|Repressor Proteins 32 JPH1 21719870 Aesthet Surg J 2011 10.1177/1090820X11412487 3 0 0 121 Humans|*Lipectomy|*Abdominoplasty|Surgical Flaps|Abdominal Wall|Abdominal Muscles|*Margins of Excision 18 JPH1 21587050 Ann Plast Surg 2011 10.1097/SAP.0b013e31820b3aa8 5 0 0 121 *Facial Hemiatrophy|*Follow-Up Studies|*Autografts|Transplantation, Autologous|Reconstructive Surgical Procedures|Face|Adipose Tissue|Atrophy|Syndrome 18 MMRN2 22020326 Oncogene 2011 10.1038/onc.2011.487 29 4 4 55 *Vascular Endothelial Growth Factor A|KDR protein, human|*VEGFR-2|*Neovascularization, Pathologic|FLT1 protein, human|VEGFR-1|Cell Movement|Neovascularization, Physiologic|Endothelial Cells|Signal Transduction|Cell Proliferation|Tumors|Phosphorylation 18 MTCH1 21856303 FEBS Lett. 2011 PMC7164028 10.1016/j.febslet.2011.08.012 7 1 0 78 bcl-2 Homologous Antagonist-Killer Protein|bcl-2-Associated X Protein|bcl-X Protein|Apoptosis Regulatory Proteins|BH3 Interacting Domain Death Agonist Protein|Apoptosis|Bcl-2-Like Protein 11|Proto-Oncogene Proteins c-bcl-2|Proto-Oncogene Proteins|Mitochondrial Membrane, Outer|Protein Structure, Tertiary|Membrane Proteins|Mitochondria|Protein Binding 18 MTCH1 21496424 Chin. 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Genet. 2011 10.1038/jhg.2011.16 4 0 0 79 Humans|Child|*Arthritis, Juvenile|DNA Copy Number Variations|*Gene Cluster|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|Genes, Regulator 18 NSUN5 21961235 Zhonghua Nan Ke Xue 2011 0 0 0 43 Male|Animals|Mice|*Two-Hybrid System Techniques|cDNA Library|Protein Interaction Mapping|TYRP1 protein, human|*Membrane Glycoproteins|Protein Binding 18 PHF3 22096494 PLoS ONE 2011 PMC3210123 10.1371/journal.pone.0026726 29 2 0 73 Humans|*Genome-Wide Association Study|*Alcoholism|Australia|European Continental Ancestry Group|SNPs|African Americans|Genetic Predisposition to Disease|PTP4A1 protein, human|Membrane Proteins|Quantitative Trait Loci|HapMap|Cell Cycle Proteins|Case-Control Studies|Linkage Disequilibrium|Protein Tyrosine Phosphatases|*Genes, Duplicate 19 RASEF 21890458 Carcinogenesis 2011 10.1093/carcin/bgr205 6 8 0 44 Humans|*Small GTPase Activators|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|*Apoptosis|CASP3 protein, human|Caspase 3|K562 Cells|Phosphorylation|Pyrimidines|Signal Transduction|Membrane Potential, Mitochondrial|*Progenitor Cells|Monomeric GTP-Binding Proteins 18 SLC35F2 21874247 Mol Med Rep 2011 10.3892/mmr.2011.572 8 0 2 61 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Prognosis|Carcinoma, Squamous Cell|Lung|Lymphatic Metastasis|RNA, Messenger|Western Blotting|SLC35F2 protein, human|Membrane Transport Proteins 18 SLC35F2 21660214 Int J Alzheimers Dis 2011 PMC3109875 10.4061/2011/729478 24 0 3 61 Humans|Alzheimer Disease 10|*Alzheimer Disease|*DNA Copy Number Variations|*Cognitive Impairment, Mild|Neuroimaging|Genome-Wide Association Study|*Genomics|Case-Control Studies|European Continental Ancestry Group|SLC35F2 protein, human|Membrane Transport Proteins 18 SNORD48 22072212 Tumour Biol. 2011 10.1007/s13277-011-0259-1 12 0 1 0 *Arsenic Trioxide|*Leukemia, Promyelocytic, Acute|*Arsenic|*miRNA|Arsenicals|Apoptosis|Oxides|Cell Proliferation|Antineoplastic Agents|Cell Cycle|Cell Line, Tumor|Downregulation|Upregulation|*Gene Expression 18 TESMIN 21664405 Toxicology 2011 10.1016/j.tox.2011.05.013 4 1 1 39 Rats|Male|Animals|*Cadmium|*Coculture Techniques|Apoptosis|Membrane Potential, Mitochondrial|Reactive Oxygen Species|Sertoli Cells|Caspase 3|Oxidative Stress|DNA Fragmentation|Cell Survival|Cytochrome c|tesmin|Metallothionein|Cell Death|Glutathione 18 wdr81 21885617 Genome Res. 2011 PMC3227090 10.1101/gr.126110.111 19 0 3 101 Humans|Animals|Child|Cerebellar Hypoplasia|*Cerebellum|*Nervous System Malformations|*Homozygote|*Locomotion|*Developmental Disabilities|Cerebellar Ataxia|Mental Retardation|Gait|Imaging, Magnetic Resonance|Brain|Atrophy|VLDL receptor|Receptors, LDL|Missense Mutation|Pedigree|Phenotype|*Extended Family 18 ARL5B 20934677 Am. J. Obstet. Gynecol. 2010 PMC3011026 10.1016/j.ajog.2010.08.043 40 6 3 224 Pregnancy|Humans|Female|*Pre-Eclampsia|Decidua|Gene Expression Profiling|Case-Control Studies 18 ARL5B 20932310 BMC Neurol 2010 PMC2964649 10.1186/1471-2377-10-90 46 12 3 224 Humans|*Genome-Wide Association Study|*Case-Control Studies|Alzheimer Disease|Amyloid beta-Peptides|tau Proteins|Peptide Fragments|Apolipoprotein E4|Cognitive Impairment, Mild|Apolipoproteins E|Apo E-2|Genotype|Polymorphism, Single Nucleotide|Biomarkers|Phosphorylation|Cognition 18 ARL5B 20547129 Neuron 2010 PMC3168544 10.1016/j.neuron.2010.04.033 43 20 5 224 18 CAMK1G 20143453 J. Biochem. Mol. Toxicol. 2010 10.1002/jbt.20324 0 0 0 35 Rats|Animals|*Calcium|*Protein Kinase|*Calmodulin|*Rats, Long-Evans|*Pyrethroids|Permethrin|Insecticides|Nitriles|Neurons|*RNA Splicing|Glutamic Acid|Frontal Cortex|Cells, Cultured|mRNA 18 CNTNAP5 20451256 J Affect Disord 2010 10.1016/j.jad.2010.04.007 41 0 5 24 Humans|*Bipolar Disorder|*Genome-Wide Association Study|Norway|Genetic Predisposition to Disease|Schizophrenia|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Case-Control Studies|Iceland 18 CNTNAP5 20346443 Biol. Psychiatry 2010 PMC2941017 10.1016/j.biopsych.2010.02.002 52 2 6 24 Child|Humans|*Autistic Disorder|*Dyslexia|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|DNA Copy Number Variations|Child Development Disorders, Pervasive|Nerve Tissue Proteins|GTPase-Activating Proteins|DOCK4 protein, human 18 KLHL10 20643358 Dev. Cell 2010 10.1016/j.devcel.2010.06.009 33 0 0 45 Male|Animals|*Spermatids|Drosophila|Drosophila Proteins|Caspases|Drosophila melanogaster|*Caspase Inhibitors|Spermatogenesis|*Cell Differentiation|Apoptosis|Cullin Proteins|Mitochondria|Amino Acid Sequence|Cell Death|Ubiquitins 18 KLHL10 20218307 Zhonghua Nan Ke Xue 2010 1 0 0 45 Humans|Male|*Oligospermia|*Azoospermia|*Infertility, Male|*Asthenozoospermia|Gene Frequency|Polymorphism, Genetic|*Mutation|Spermatogenesis|Genetic Predisposition to Disease|Genotype|Polymerase Chain Reaction|Case-Control Studies 18 LACTB 20503261 Diabetes Metab. Res. Rev. 2010 10.1002/dmrr.1080 41 2 12 114 dulaglutide|*Glucagon-Like Peptide 1|Diabetes Mellitus, Type 2|*Immunoglobulin Fc Fragments|*Recombinant Fusion Proteins|Glucagon-Like Peptide-1 Receptor|Exenatide|Receptors, Glucagon|Liraglutide|Hypoglycemic Agents|Venoms|DPP4 protein, human|Dipeptidyl Peptidase IV|Insulin 18 LMLN 21136063 Mamm. Genome 2010 10.1007/s00335-010-9305-3 15 0 2 98 Swine|Animals|Male|MUC4 protein, human|*Mucin-4|Enterotoxigenic Escherichia coli|Fimbriae, Bacterial|Escherichia coli Infections|Fimbriae Proteins|Swine Diseases|Escherichia coli Proteins|Bacterial Adhesion|Linkage Disequilibrium|Diarrhea|Phenotype|Genotype|Genetic Predisposition to Disease|Mucins|SNPs|Pedigree 18 NLRP9 20403124 Reprod. Domest. Anim. 2010 10.1111/j.1439-0531.2010.01617.x 9 0 1 79 Female|Cattle|Animals|Mice|*In Vitro Oocyte Maturation Techniques|Oocytes|Ovarian Follicle|Embryonic Development|Gene Expression Regulation, Developmental|Gene Expression Profiling|RNA, Messenger 18 NSUN5 20504288 Stem Cell Res Ther 2010 PMC3226301 10.1186/scrt7 9 0 0 43 Swine|Animals|*Mesenchymal Stem Cells|*Transcriptome|*Reproducibility of Results|*Cell Differentiation|*Adult Stem Cells|Osteogenesis|Adipogenesis|*Real-Time Polymerase Chain Reaction|Bone Marrow Cells|Adipose Tissue|Cells, Cultured|Gene Expression Profiling|*Computational Biology 18 SLFN5 20956525 J. Biol. Chem. 2010 PMC3001013 10.1074/jbc.M110.151076 25 0 2 77 Humans|*Interferon-alpha|Melanoma|Gene Expression Regulation, Neoplastic|Melanocytes|Cell Line, Tumor|Cell Cycle Proteins|Cell Proliferation|Antiviral Agents|Drug Resistance, Neoplasm|RNA, Messenger 18 SLFN5 20819478 Zhonghua Zhong Liu Za Zhi 2010 0 0 0 77 Humans|*Small Cell Lung Carcinoma|pleiotrophin|*Carrier Proteins|*Cytokines|*Genes, Neoplasm|RNA Interference|Lung Neoplasms|RNA, Small Interfering|AMOT protein, human|Intercellular Signaling Peptides and Proteins|Cell Line, Tumor|Transfection|Genetic Vectors|RNA, Messenger|Vascular Endothelial Growth Factor A|Neovascularization, Pathologic|Membrane Proteins 18 CAMK1G 19657032 J. Neurosci. 2009 PMC2763510 10.1523/JNEUROSCI.1544-09.2009 0 32 1 35 *Axons|*Neurons|*Calmodulin-Kinase|*Hippocampus|Neurite|Growth Cones|Calcium-Calmodulin-Dependent Protein Kinase Kinase|Calcium-Calmodulin-Dependent Protein Kinase Type 1|Neurogenesis|Signal Transduction|Cells, Cultured 18 CHURC1 20034103 Dev. Dyn. 2009 PMC2962425 10.1002/dvdy.22201 1 23 0 49 Animals|*Zebrafish|*Fibroblast Growth Factor|Zebrafish Proteins|Somites|*Signal Transduction Pathways|Body Patterning|Mesoderm|*Transcription Factors|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Gastrulation|Zinc Finger|Trans-Activators|*Embryonic Development|Cell Movement|her1 protein, zebrafish|Basic Helix-Loop-Helix Transcription Factors 18 CHURC1 19681734 J Perinat Med 2009 10.1515/JPM.2009.103 16 0 1 49 Pregnancy|Humans|Female|*Pre-Eclampsia|Leukocytes, Mononuclear|*Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Placenta|*Biomarkers|Real Time Polymerase Chain Reaction 18 CNTNAP5 19721433 Mol. Psychiatry 2009 PMC2888895 10.1038/mp.2009.89 52 3 4 24 Humans|*Antipsychotic Agents|*Pharmacogenomic Testing|Genome-Wide Association Study|Risperidone|Olanzapine|Quetiapine|Dibenzothiazepines|Schizophrenia|Perfenazine|Benzodiazepines|ziprasidone|Piperazines|Thiazoles|Treatment Outcome|SNPs 18 CNTNAP5 19236961 Eur J Med Genet 2009 10.1016/j.ejmg.2009.02.004 10 0 0 24 Humans|Mice|Animals|*Language|*Chromosome Aberrations|*Cytogenetic|Mowat-Wilson syndrome|Intellectual Disability|Translocation, Genetic|Comparative Genomic Hybridization|Chromosome Deletion|In Situ Hybridization, Fluorescence|Karyotyping|Microcephaly|Chromosome Breakage|Gene Rearrangement|Chromosomes, Artificial, Bacterial|Phenotype|Hirschsprung Disease|Facies|CNTNAP2 protein, human 18 GALK2 19874134 J Enzyme Inhib Med Chem 2009 10.3109/14756360903179492 2 0 0 63 Humans|*Acetylgalactosamine|Kinetics|Substrate Specificity|Galactokinase|Phosphorylation|Catalysis|Mutagenesis, Site-Directed|Carbohydrate Metabolism|Adenosine Triphosphate|Escherichia coli|methyl-galactopyranoside|Galactose|GALK2 protein, human 18 LACTB 19858488 Proc. Natl. Acad. Sci. U.S.A. 2009 PMC2767363 10.1073/pnas.0906734106 19 0 0 114 Animals|*Mitochondria|Mitochondrial Proteins|Membrane Proteins|Amino Acid Sequence|*Cytoskeleton|*Protein Biosynthesis|beta-Lactamases|Intracellular Membranes|Penicillin-Binding Proteins 18 MIR193A 19864316 Biol. Reprod. 2009 PMC2842492 10.1095/biolreprod.109.081059 78 1 8 1 Female|Humans|*Messenger RNA|*MicroRNAs|*Endometrium|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Luteal Phase|Progesterone|Up-Regulation|Downregulation|Estradiol-17beta|Bioinformatics|*Genetic Profile|Genomics|MIRN582 microRNA, human 18 NLRP9 19682372 BMC Evol. Biol. 2009 PMC2735741 10.1186/1471-2148-9-202 50 2 2 79 Animals|*Mammals|Evolution, Molecular|Phylogeny|Gene Duplication|Natural Selection|Multigene Family|Oocyte|Sequence Analysis, DNA|*Systems, Reproductive|Adaptor Proteins, Signal Transducing 18 SLC35F2 19252338 Drug Metab. Pharmacokinet. 2009 10.2133/dmpk.24.91 17 0 0 61 Male|Adult|Female|Pregnancy|Humans|HeLa Cells|*Membrane Transport Proteins|mRNA|Gene Expression|Gene Expression Profiling|PCR|Tissue Distribution|SLC35D1 protein, human|Monosaccharide Transport Proteins|SLC35D2 protein, human|Nucleotide Transport Proteins|SLC35F2 protein, human|Male|Adult|Female|Pregnancy|Humans|HeLa Cells|*Membrane Transport Proteins|mRNA|Gene Expression|Gene Expression Profiling|PCR|Tissue Distribution|SLC35D1 protein, human|Monosaccharide Transport Proteins|SLC35D2 protein, human|Nucleotide Transport Proteins|SLC35F2 protein, human|Male|Adult|Female|Pregnancy|Humans|HeLa Cells|*Membrane Transport Proteins|mRNA|Gene Expression|Gene Expression Profiling|PCR|Tissue Distribution|SLC35D1 protein, human|Monosaccharide Transport Proteins|SLC35D2 protein, human|Nucleotide Transport Proteins|SLC35F2 protein, human 18 ARL5B 18382472 J. Cereb. Blood Flow Metab. 2008 10.1038/jcbfm.2008.19 23 0 1 224 18 CAMK1G 19017407 BMC Genomics 2008 PMC2626604 10.1186/1471-2164-9-546 7 11 0 35 Animals|Rats|decamethrin|*Permethrin|*Insecticides|*Pyrethroids|Nitriles|*Frontal Cortex|Neurons|Neurotoxicity Syndromes|Cells, Cultured|Dose-Response Relationship, Drug 18 CHURC1 19087513 Zhonghua Fu Chan Ke Za Zhi 2008 0 0 0 49 Pregnancy|Humans|Female|*Pre-Eclampsia|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Placenta|*Leukocytes|*Blood Pressure|Up-Regulation 18 CPXM2 18198839 J. Nat. Prod. 2008 10.1021/np070356p 15 0 1 18 Mice|Animals|*Coral|*Oxygen|Diterpenes|Nitric Oxide Synthase Type II|Cyclooxygenase 2 Inhibitors|Macrophage|Drug Screening Assays, Antitumor|Lipopolysaccharides|Cyclooxygenase 2|Anti-Inflammatory Agents, Non-Steroidal|Molecular Structure|*Oxygenators|Antineoplastic Agents|*Cell Respiration|*Respiratory Physiological Phenomena|RAW 264.7 Cells 18 gpr19 18442402 BMC Med Genomics 2008 PMC2408576 10.1186/1755-8794-1-13 200 0 13 4 Humans|*Transcriptome|*Melanoma|Skin Neoplasms|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease Progression|*Neoplasms, Second Primary 18 LACTB 18538381 J. Allergy Clin. Immunol. 2008 10.1016/j.jaci.2008.03.037 13 0 0 114 Humans|*Self Report|*Risk Factors|*Penicillins|*Drug Hypersensitivity|Skin Tests|Immunoglobulin E|Polymorphism, Single Nucleotide|Case-Control Studies 18 LACTB 18344982 Nature 2008 PMC2841398 10.1038/nature06757 421 0 16 114 Mice|Animals|Quantitative Trait Loci|Obesity|Adiposity|Crosses, Genetic|Genetic Predisposition to Disease|Networks, Gene|Phenotype|Gene Expression Profiling|Adipose Tissue|Liver|Metabolic Syndrome|Gene Expression|*DNA 18 LACTB 18226203 BMC Evol. Biol. 2008 PMC2266909 10.1186/1471-2148-8-26 11 2 1 114 Humans|Animals|*Penicillin-Binding Proteins|*Serine|*Active Site|beta Lactamases|Protein Conformation|*Bacteria|Peptidoglycan|Amino Acid Sequence|Binding Sites|Protein Binding|Models, Molecular|Crystallography, X-Ray|Penicillins|Cell Wall|LACTB protein, human|Membrane Proteins|Mitochondrial Proteins 18 MTCH1 18375015 Eur. J. Cell Biol. 2008 10.1016/j.ejcb.2008.02.004 9 2 1 78 Humans|Mice|Animals|*bcl-2-Associated X Protein|*Presenilin-1|*Mitochondria|*Apoptosis|bcl-2 Homologous Antagonist-Killer Protein|Mitochondrial Membrane, Outer|Mitochondrial Proteins|HeLa Cells|Permeability 18 MTCH1 18291114 Biochim. Biophys. Acta 2008 PMC3509497 10.1016/j.bbagen.2008.01.013 5 0 0 78 *PDZ Domains|Isoforms|Mitochondrial Proteins|Mitochondria|*Domain, Protein-Protein Interaction|Exons|Membrane Proteins|Amino Acid Sequence|Alternative Splicing|*Genes, Regulator|*Protein Domains|Sequence Homology, Amino Acid|Apoptosis|Transcription Factors|RNA Splicing|Presenilins 18 PHF3 18646010 Proteomics 2008 10.1002/pmic.200800208 6 1 0 73 Mice|Humans|Animals|HEK293 Cells|Golgi Apparatus|Uridine Diphosphate N-Acetylglucosamine|Endocytosis|N-Acetylglucosaminyltransferases|Glycans|Glycosylation|Cell Proliferation|Signal Transduction|galectin-3, human|Galectin 3|Glycoprotein 19 RASEF 18385040 Invest. Ophthalmol. Vis. Sci. 2008 10.1167/iovs.07-1135 14 1 3 44 Uveal melanoma|Melanoma, Cutaneous Malignant|*Melanoma|*Epigenesis, Genetic|Skin Neoplasms|*Genes, Suppressor|*Uveal Neoplasms|CpG Islands|Promoter Regions, Genetic|DNA Methylation|Genes, Tumor Suppressor|Gene Silencing|DNA, Neoplasm|Tumor Suppressor Proteins|Gene Expression Regulation, Neoplastic|Mutations 18 SGCZ 18683213 Hum. Mutat. 2008 10.1002/humu.20829 15 0 2 21 Humans|*Comparative Genomic Hybridization|*Exons|Dystrophin|Becker Muscular Dystrophy|Sequence Deletion|Gene Duplication|Heterozygote|Sarcoglycans|Polymerase Chain Reaction|Oligonucleotides 19 SGCZ 18625863 Arch. Neurol. 2008 10.1001/archneur.65.7.943 10 0 0 21 Generalized Epilepsy with Febrile Seizures Plus|*Febrile Seizures|*Epilepsy, Generalized|Lod Score|Genetic Linkage|Pedigree|Sodium Channel|Chromosome Mapping|Mutations 19 SLC35F2 18382472 J. Cereb. Blood Flow Metab. 2008 10.1038/jcbfm.2008.19 23 0 1 61 Mice|Animals|Rats|Swine|*Blood-Brain Barrier|*Tight Junctions|epithelial membrane protein-1|Endothelial Cells|*Neoplasm Proteins|*Receptors, Cell Surface|Occludin|Brain|Claudin-5|*Biological Transport|Cells, Cultured|Brain Ischemia 18 ARL5B 17332968 J. Assoc. Res. Otolaryngol. 2007 PMC2538354 10.1007/s10162-007-0078-7 1 0 0 224 18 CAMK1G 17598886 Genome Biol. 2007 PMC2394777 10.1186/gb-2007-8-6-r128 26 12 1 35 Mice|Animals|*Morphine|*Transcriptome|*Corpus Striatum|Mice, Inbred C57BL|Oligonucleotide Array Sequence Analysis|Analgesics, Opioid|Phenotypes|Species Specificity|Substance-Related Disorders 18 CAMK1G 17553424 Neuron 2007 10.1016/j.neuron.2007.05.021 51 3 2 35 Animals|Chlorocebus aethiops|EEF2K protein, human|*Calmodulin-Dependent Protein Kinase III|Ca(2+)-Calmodulin-Dependent Protein Kinase|*Membrane Microdomains|Neurons|Dendrites|COS Cells|Signal Transduction 18 CHURC1 17980025 BMC Dev. Biol. 2007 PMC2180179 10.1186/1471-213X-7-120 5 14 0 49 Animals|*Mesoderm|Zebrafish Proteins|*Signal Transduction|Zebrafish|*Cell Movement|Nodal Protein|Embryo, Nonmammalian|Body Patterning|Gene Expression Regulation, Developmental|Transforming Growth Factor beta|Fibroblast Growth Factors|Zinc Finger|Transcription Factor 18 CHURC1 17521969 Gene Expr. Patterns 2007 PMC1976285 10.1016/j.modgep.2007.04.002 5 1 0 49 Animals|*Zebrafish|*Transcription Factor|Zebrafish Proteins|*Zinc Finger|Gastrula|Embryo, Nonmammalian|Body Patterning|Blastula|Gastrulation|Gene Expression Regulation, Developmental|Mesoderm|Fibroblast Growth Factors|Trans-Activators|Transforming Growth Factor beta|Embryonic Development|Cell Movement|Signal Transduction 18 DIRAS1 17544445 J. Mol. Biol. 2007 10.1016/j.jmb.2007.05.015 10 0 0 155 Protein Binding|Protein Interaction Mapping|Binding Sites|Models, Molecular|ras Proteins|Bioinformatics|Thermodynamics 18 gpr19 17204602 Stem Cells 2007 PMC1906587 10.1634/stemcells.2006-0352 134 0 6 4 Humans|*Human Embryonic Stem Cells|*Transcriptome|Embryonic Stem Cells|Cell Differentiation|POU5F1 protein, human|Octamer Transcription Factor-3|Transcription Factors|Pluripotent Stem Cells|Homeodomain Proteins|Genes, Homeobox|Cell Line|Gene Expression Profiling|Microarray Analysis|Internet|HELLS protein, human|DNA Helicases 18 JPH1 17476457 J. Hum. Genet. 2007 10.1007/s10038-007-0149-y 38 0 3 121 Humans|Animals|Mice|junctophilin|*Mice, Knockout|*Membrane Proteins|*Cardiomyopathy, Hypertrophic|Ryanodine Receptor|*Mutation|Calcium Signaling|Myocytes, Cardiac|Heterozygote|Heart Failure|Diabetes Mellitus, Type 2 18 KLHL10 17982253 Cell. Physiol. Biochem. 2007 10.1159/000110431 4 0 0 45 Humans|*Fluorescence|*Plasmid|Protein Interaction Mapping|Luminescent Proteins|Protein Binding|Microscopy, Fluorescence|Transcription Factors|Transfection|*Complement Factor B|Genetic Vectors|Bacterial Proteins 18 KLHL10 17880263 PLoS Biol. 2007 PMC1976628 10.1371/journal.pbio.0050251 46 31 2 45 Animals|Male|Humans|*Drosophila|Spermatids|Drosophila Proteins|Caspases|Drosophila melanogaster|*Cell Differentiation|*Cytoplasm|Cullin Proteins|*Cell Death|Testis|Apoptosis|*Proteolysis|Ubiquitin|Infertility, Male|*Protein Processing, Post-Translational 18 MTCH1 17670888 Am. J. Physiol., Cell Physiol. 2007 10.1152/ajpcell.00431.2006 12 0 4 78 Humans|Rats|Animals|*Mitochondrial Membranes|Protein, Mitochondrial|*Isoforms|Mitochondria|Amino Acid Sequence|Integral Membrane Protein|Luminescent Proteins|Apoptosis|Green Fluorescent Proteins|Protein Transport|HeLa Cells|Alternative Splicing 18 RASEF 17448446 Biochem. Biophys. Res. Commun. 2007 10.1016/j.bbrc.2007.03.206 13 2 1 44 Humans|*GTPase|HeLa Cells|Amino Acid Sequence|*EF Hand Motifs|Sequence Homology, Amino Acid|Protein Transport|*Protein Domains|Transfection 18 SLC35F2 17581869 Proc. Natl. Acad. Sci. U.S.A. 2007 PMC1904118 10.1073/pnas.0704182104 12 0 0 61 Humans|Cats|Animals|*Peptide Library|Feline Leukemia Virus|*env Protein|Leukemia, Feline|*Retroviridae|Receptors, Virus|Viral Envelope Proteins|Amino Acid Sequence|Virus Entry|*Carrier Proteins|Cell Line|Membrane Transport Proteins|SLC35F2 protein, human 18 TESMIN 18057042 J. Exp. Bot. 2007 10.1093/jxb/erm215 17 0 2 39 Female|Male|*Arabidopsis|tesmin|*Cysteine|*Zinc|Phylogeny|*Metallothionein|Arabidopsis Proteins|Ovule|Genes, Plant|DNA, Plant|Plant Proteins|Amino Acid Sequence|Cell Division|*Protein Domains|Alleles|Phenotypes|Fertility|TSO1 protein, Arabidopsis 18 TESMIN 17360778 Development 2007 PMC2229809 10.1242/dev.000521 37 1 3 39 Male|Animals|*Drosophila|*Transcriptional Activation|tesmin|Caenorhabditis elegans|*Metallothionein|Spermatocytes|Drosophila Proteins|Spermatogenesis|Cell Cycle Proteins|Meiosis|Spermatids|Nuclear Proteins|Drosophila melanogaster|Cell Nucleus|Chromatin|Transcription Factors|Genes, Insect|Testis 18 CAMK1G 16702976 Mol. Psychiatry 2006 10.1038/sj.mp.4001835 49 0 1 35 Humans|Animals|Mice|Adult|BDNF protein, human|*Brain-Derived Neurotrophic Factor|*Transcriptome|*Neocortex|Neurons|Neurotransmission|*Embryogenesis|Cortex, Prefrontal|Oligonucleotide Microarrays|RNA, Messenger|Gene Expression Regulation, Developmental|Gene Expression Profiling 18 CHURC1 16858397 EMBO J. 2006 PMC1538554 10.1038/sj.emboj.7601238 20 4 1 49 Animals|*Xenopus laevis|*Mesoderm|Xenopus Proteins|Embryonic Induction|Gastrula|Brachyury protein|T-Box Domain Proteins|*Nervous System|*Cell Differentiation|Homeodomain Proteins|POU5F1 protein, human|*Octamer Transcription Factor-3|Fetal Proteins|Ectoderm|Transcription Factors|Gene Expression Regulation, Developmental|Endoderm|Fibroblast Growth Factor 18 CNTNAP5 16845472 Mamm. Genome 2006 10.1007/s00335-005-0157-1 8 0 1 24 Humans|Rats|Mice|Dogs|Animals|*Rodent|Gene Duplications|Genome|Chimpanzee|Evolution, Molecular|Opossum|Phylogeny|Chromosome Mapping|Hominidae|Species Specificity|CNTNAP1 protein, human|Cell Adhesion Molecules, Neuronal|TYRP1 protein, human|Membrane Glycoproteins 18 JPH1 16427970 Clin Plast Surg 2006 10.1016/j.cps.2005.09.003 5 0 0 121 Humans|*Lipectomy|Esthetics|Obesity|Body Weight|Postoperative Complications 18 KLHL10 17047026 Hum. Mol. Genet. 2006 10.1093/hmg/ddl417 39 0 0 45 Humans|Male|*RNA|*Infertility, Male|Spermatozoa|Spermatogenesis|Oligospermia|Sperm Count|Semen|Testis|*Mutations|mRNA|Gene Expression|Proteins|PCR 18 MTCH1 16709241 Mol. Cancer 2006 PMC1524802 10.1186/1476-4598-5-20 52 4 3 78 Humans|*5 Fluorouracil|*Colon Cancer|Antimetabolites, Antineoplastic|Cell Cycle|*Colon|Drug Resistance, Neoplasm|HCT116 Cell|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Antineoplastic Agents|Oligonucleotide Array Sequence Analysis|Apoptosis|*B Cells 18 GALK2 16006554 J. Biol. Chem. 2005 10.1074/jbc.M505730200 33 0 0 63 Humans|*Acetylgalactosamine|Galactokinase|Protein Conformation|Substrate Specificity|Binding Sites|Models, Molecular|Galactose|Crystallography, X-Ray|Amino Acid Sequence|Catalysis|Models, Chemical|Active Site|Phosphorylation|MgATP|GALK2 protein, human 18 GALK2 15733694 Public Health 2005 10.1016/j.puhe.2004.04.009 21 0 0 63 Humans|*Salmonella typhi|*Typhoid Fever|Nigeria|Salmonella paratyphi A|Paratyphoid Fever|Microbial Sensitivity Tests|Drug Resistance, Multiple, Bacterial|Anti-Bacterial Agents 18 KLHL10 16162871 Biol. Reprod. 2005 10.1095/biolreprod.105.045484 22 4 2 45 Male|Humans|Adult|*Protein A|*Spermiogenesis|Spermatids|Testis|Northern Blot|Amino Acid Sequence|Nuclear Proteins|Yeast Two-Hybrid Assay|Blotting, Western|In Situ Hybridization|mRNA 18 LACTB 16202624 Protein Expr. Purif. 2005 10.1016/j.pep.2005.08.006 7 0 0 114 Mice|Animals|*Escherichia coli|*Serine Protease|*Serine Endopeptidases|Recombinant Proteins|Amino Acid Sequence|Recombinant Fusion Proteins|Lactb protein, mouse|Membrane Proteins|beta Lactamase|*Mitochondria|Affinity Chromatography|Protein, Mitochondrial|Protein Structure, Secondary|Penicillin Binding Protein|cDNA|Ribosomal Proteins 18 PHF3 15906353 Int. J. Cancer 2005 10.1002/ijc.20929 28 0 1 73 Humans|*Glioblastoma|*Autoantibodies|Brain Neoplasms|Glioma|Tumor Antigens|Amino Acid Sequence 19 RASEF 16174859 J. Natl. Cancer Inst. 2005 10.1093/jnci/dji280 9 0 0 44 Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|Dysplastic Nevus Syndrome|Genetic Linkage|Lod Score|Genes, p16|Pedigree|BRCA2 protein, human|BRCA2 Protein|BRCA1 protein, human|BRCA1 Protein|Chromosome Mapping|Mutations, Germline|Genetic Predisposition to Disease|*Chromosome Structures|Haplotype|*Eye 18 RASEF 16015647 Genes Chromosomes Cancer 2005 10.1002/gcc.20236 19 0 0 44 Humans|*Genes, Suppressor|*Leukemia, Myeloid, Acute|Chromosome Deletion|Chromosomal Aberration|Cytogenetic Analysis|Mutation|In Situ Hybridization, Fluorescence|Microsatellite Markers|UBQLN1 protein, human|Carrier Proteins|Cell Cycle Proteins 18 CDHR5 15028844 Pediatr. Res. 2004 10.1203/01.PDR.0000125260.46861.32 4 0 0 51 Animals|Mice|Humans|*Cadherins|cDNA|*Intestine|Amino Acid Sequence|Base Sequence|Cloning, Molecular|In Situ Hybridization|mRNA|Cell Adhesion|cDNA Library|Liver|Tissue Distribution|Gene Expression Regulation, Developmental|Intestinal Epithelium|Integral Membrane Protein 19 gpr19 15452705 Cell Tissue Res. 2004 10.1007/s00441-004-0948-9 3 0 1 4 Male|Pregnancy|Female|Animals|Mice|GPRC5C protein, human|*G-Protein-Coupled Receptors|*Embryogenesis|*Neurons|Nerve Tissue Proteins|Brain|Signal Transduction|Protein Binding|In Situ Hybridization|RNA, Messenger|Amino Acid Sequence|Nervous System|Cloning, Molecular|Hippocampus|Cell Differentiation 18 gpr19 15090189 Assay Drug Dev Technol 2004 10.1089/15406580360545053 12 0 2 4 GPRC5C protein, human|*Receptors, G-Protein-Coupled|*Signal Transduction Pathway|Ligands|Transfection 18 gpr19 15053975 Gene Expr. Patterns 2004 10.1016/j.modgep.2003.11.003 11 0 2 4 Male|Animals|Mice|*Transcriptome|Spermatocytes|Spermatogenesis|Gene Chips|Spermatogonia|Gene Expression Profiling|Testis|Meiosis|Meiotic Prophase I|Genome|Gene Expression Regulation, Developmental|Blotting, Northern 18 KLHL10 15136734 Proc. Natl. Acad. Sci. U.S.A. 2004 PMC419685 10.1073/pnas.0308025101 35 0 1 45 Humans|Male|Mice|Animals|*Haploinsufficiency|*Mice, Inbred C57BL|Spermatids|Spermiogenesis|Testis|Infertility, Male|Spermatozoa|Acrosome|Nuclear Proteins|Cell Differentiation|Mutation 18 LMLN 15037580 Invest. Ophthalmol. Vis. Sci. 2004 10.1167/iovs.03-0324 0 0 0 98 *Nystagmus, Pathologic|Eye Movements|Electronystagmography|Saccades|Strabismus 18 MMRN2 15177571 Genomics 2004 10.1016/j.ygeno.2003.12.014 7 0 0 55 Mice|Animals|Snca protein, mouse|*alpha-Synuclein|multimerin|*Mice, Inbred C57BL|*Blood Proteins|gamma-Synuclein|Phenotypes|Mutation|Mmrn1 protein, mouse|Cell Adhesion Molecules 18 MTCH1 15174014 Ann. Neurol. 2004 10.1002/ana.20101 107 2 8 78 Animals|Mice|*Amyloid beta-Protein Precursor|*Alzheimer Disease|Plaque, Amyloid|Mice, Transgenic|Amyloid beta-Peptides|Presenilin-1|Long-Term Potentiation|Memory|Maze Learning|Cognition Disorders|Excitatory Postsynaptic Potentials|Hippocampus|Synaptic Transmission|Disease Models, Animal|Synaptic Plasticity|Brain|Behavior, Animal 18 SLFN5 15351786 Int. Immunol. 2004 10.1093/intimm/dxh155 56 2 3 77 Mice|Animals|*RNA Helicase|*DNA Helicases|*RNA Motif|*Cell Differentiation|Gene Expression Regulation|Transcriptional Activation|IRF1 protein, human|Interferon Regulatory Factor-1|Macrophages|Lymphocyte Activation|RNA, Messenger|T Cells|Cell Line|Amino Acid Sequence 18 ARL5B 12853149 Gene 2003 10.1016/s0378-1119(03)00584-5 1 1 0 224 18 CAMK1G 12753081 J. Neurochem. 2003 10.1046/j.1471-4159.2003.01760.x 4 1 0 35 Animals|Rats|CAMK1 protein, human|*Calcium-Calmodulin-Dependent Protein Kinase Type 1|*Isoforms|*Alternative Splicing|Calcium-Calmodulin-Dependent Protein Kinases|CaMKK|In Situ Hybridization|Neurons|Blotting, Northern|Nucleotide Sequence|Phosphorylation|Amino Acid Sequence|Hippocampus|Transfections|Brain|mRNA|Cloning, Molecular 18 CAMK1G 12637513 J. Biol. Chem. 2003 10.1074/jbc.M300578200 17 1 1 35 CAMK1 protein, human|Calcium-Calmodulin-Dependent Protein Kinase Type 1|Ca(2+)-Calmodulin-Dependent Protein Kinase|*Cloning, Molecular|*Neurons|*Protein-Serine-Threonine Kinases|Phosphorylation|cDNA|Amino Acid Sequence|cAMP Response Element Binding Protein|Serine|Transfection|Protein Binding|Cell Nucleus 18 CDHR5 12589428 Hum. Genet. 2003 10.1007/s00439-003-0907-7 4 0 0 51 Adult|Mice|Humans|Animals|Parental Imprinting|Methylations, DNA|Genes, Tumor Suppressor|Wilms Tumor|Insulin-Like Growth Factor II|RNA, Untranslated|RNA, Long Noncoding|Alleles|Muscle Proteins|DNA|Fetus|Heterozygote|Kidney Neoplasms|HRAS protein, human|Proto-Oncogene Proteins p21(ras)|DUSP8 protein, mouse|Dual-Specificity Phosphatases 19 CHURC1 14651851 Cell 2003 10.1016/s0092-8674(03)00927-9 65 1 3 49 Animals|*Gastrulation|*Neurulation|*Transcription Factors|*Zinc Finger|Brachyury protein|T-Box Domain Proteins|Fetal Proteins|Mesoderm|Embryonic Induction|Homeodomain Proteins|Gastrula|Xenopus Proteins|Endoderm|Repressor Proteins|Trans-Activators|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Amino Acid Sequence 18 TESMIN 14648882 Mol. Reprod. Dev. 2003 10.1002/mrd.20007 12 0 0 39 Male|Female|Animals|Mice|tesmin|*Metallothionein|Meiosis|Testis|Spermatogenesis|SYCP1 protein, human|Nuclear Proteins|Ovary|In Situ Hybridization|Spermatocytes|Amino Acid Sequence|Gene Expression Profiling|mRNA|*Cell Nucleus Division 18 TESMIN 12606435 Biol. Reprod. 2003 10.1095/biolreprod.102.005603 10 0 0 39 Male|Mice|Animals|tesmin|*Metallothionein|*Spermatogenesis|Spermatids|Testis|Spermatocytes|Base Sequence|cDNA|Amino Acid Sequence|In Situ Hybridization|Blotting, Northern|Meiosis|Cloning, Molecular|Cell Nucleus|Immunohistochemistry|Cytoplasm 18 CDHR5 12167596 Am. J. Physiol. Renal Physiol. 2002 10.1152/ajprenal.00012.2002 8 0 2 51 Adult|Female|Pregnancy|Animals|Humans|Mice|Dogs|In Situ Hybridization, Fluorescence|Cadherins|Amino Acid Sequence|*Kidneys|Cloning, Molecular|Sequence Alignment|*Fetus|Cell Adhesion|Transfection|Cell Line|Sequence Homology, Amino Acid|Cell Adhesion Molecules|Gene Expression Regulation, Developmental|Cell Aggregation|Mucin|*Prenatal Care 19 CPXM2 12424787 Microsc. Res. Tech. 2002 10.1002/jemt.10203 63 0 8 18 *Caloric Restriction|*Inflammation|NF-kappa B|Oxidative Stress|CHUK protein, human|IkappaB Kinase|NOS2 protein, human|Nitric Oxide Synthase Type II|Redox|Reactive Oxygen Species|Anti-Inflammatory Agents|TNF protein, human|TNFalpha|Cyclooxygenase 2 18 DIRAS1 12194967 J. Biol. Chem. 2002 10.1074/jbc.M202150200 13 1 0 155 Humans|*ras GTPases|HEK293 Cells|Amino Acid Sequence|Guanosine Triphosphate|Signal Transduction|Sequence Homology, Amino Acid|Mitogen-Activated Protein Kinases 18 DIRAS1 12107278 Proc. Natl. Acad. Sci. U.S.A. 2002 PMC125049 10.1073/pnas.142193799 16 1 0 155 Humans|Animals|Mice|*Genes, Tumor Suppressor|*Monomeric GTP-Binding Proteins|Downregulation|Amino Acid Sequence|mRNA|Tumor Suppressor Proteins|Cell Line|ras Proteins|Cell Cycle|Guanosine Triphosphate|Astrocytoma|Tumor Cells, Cultured|Transfection|3T3 Cells 18 LACTB 12164938 J. Invest. Dermatol. 2002 10.1046/j.1523-1747.2002.01793.x 6 0 0 114 Humans|*Keratinocytes|HSPB1 protein, human|*Heat Shock Protein 27|*Cell Differentiation|Heat-Shock Proteins|Neoplasm Proteins|Squamous Carcinoma|Skin Neoplasms|mRNA|Cells, Cultured|Tumor Cells, Cultured|Northern Blot|Gene Expression 18 LMLN 12076015 Doc Ophthalmol 2002 10.1023/a:1015299930849 15 0 1 98 Humans|Dogs|Animals|*Nystagmus, Pathologic|Eye Movements|Nystagmus, Congenital|Oculomotor Muscles|Visual Acuity|Fixation, Ocular 18 LMLN 11762236 Biol Cybern 2002 10.1007/s004220100275 3 0 0 98 Humans|*Nystagmus, Pathologic|*Vision, Ocular|Saccades|Eye Movements|Fovea Centralis|*Models, Biological|Model, Computer|*Face 18 MTCH1 12377771 J. Biol. Chem. 2002 10.1074/jbc.M209613200 19 4 2 78 *Protein, Mitochondrial|*Presenilin-1|Mitochondria|Caspases|Apoptosis|bcl-2-Associated X Protein|Caspase 9|Proto-Oncogene Proteins c-bcl-2|Caspase 8|Cell Death|Carrier Proteins|Cytochrome c|Caspase Inhibitors|Poly ADP Ribose Polymerase|Presenilin 2 18 NSUN5 11978965 Cytogenet. Cell Genet. 2002 10.1159/000057012 33 0 1 43 *Williams Syndrome|Gene Deletion|Base Sequence|Chromosome Mapping|Elastin|Sequence Alignment|Amino Acid Sequence|Transcription, Genetic|Chromosome Deletion|Phenotype|Pseudogenes 18 PHF3 11856869 Cytogenet. Cell Genet. 2002 10.1159/000048804 9 0 0 73 Humans|*Glioma|Glioblastoma|Brain Neoplasms|Astrocytomas|Amino Acid Sequence|RNA, Neoplasm|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Tumor Suppressor Proteins|Transcription Factors|RNA, Messenger|DNA, Complementary|Brain 19 TESMIN 11803038 J. Inorg. Biochem. 2002 10.1016/s0162-0134(01)00377-4 9 2 0 39 Mice|Male|Animals|tesmin|*Metallothionein|*Testis|*Active Transport, Cell Nucleus|Spermatocytes|*Metals, Heavy|TYRP1 protein, human|Amino Acid Sequence|*Membrane Glycoproteins|Meiosis|Blotting, Northern|Base Sequence|cDNA|In Situ Hybridization|Cytoplasm|Cell Nucleus|Cadmium 18 LACTB 11707067 Genomics 2001 10.1006/geno.2001.6643 12 0 0 114 Humans|Female|Animals|Cattle|Mice|Rats|Rabbits|Swine|*Serine|*beta Lactamase|Drosophila melanogaster|*Proteins|Sequence Alignment|cDNA|Intron|Amino Acid Sequence|Exons|Blotting, Northern|Base Sequence|Chromosome Mapping|*Genomics|Sequence Homology, Amino Acid|mRNA|Cloning, Molecular|Caenorhabditis elegans|Sequence Analysis, DNA 18 PHF3 11464277 Oncogene 2001 10.1038/sj.onc.1204552 13 0 1 73 Humans|*Glioblastoma|Brain Neoplasms|Astrocytoma|immunoglobulin B|*Immunoglobulins|Amino Acid Sequence|Transcription Factor|Brain 19 CDHR5 10801787 J. Biol. Chem. 2000 10.1074/jbc.M000234200 9 0 2 51 *Mucin|MUC1 protein, human|*Mucin-1|Amino Acid Sequence|Cadherins|Cloning, Molecular|Sequence Alignment|Base Sequence|Cell Adhesion|cDNA|In Situ Hybridization|Sequence Homology, Amino Acid|Cell Adhesion Molecules|Glycosylations|Transfection|Gene Expression Regulation, Developmental 19 CPXM2 10073577 DNA Cell Biol. 1999 10.1089/104454999315565 6 0 0 18 18 gpr19 10480372 Hum. Genet. 1999 10.1007/s004399900083 0 0 0 4 ETS translocation variant 6 protein|Proto-Oncogene Proteins c-ets|Repressor Proteins|DNA-Binding Proteins|Transcription Factors|*Chromosome Mapping|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|Genes, Tumor Suppressor|Microtubule-Associated Proteins|*Chromosome Structures|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Exons|Microsatellite Repeats|Loss of Heterozygosity 18 LMLN 10494944 J Neuroophthalmol 1999 2 0 0 98 *Nystagmus, Congenital|*Down Syndrome|Nystagmus, Pathologic|Eye Movements|Strabismus|Visual Acuity 18 MTCH1 10551805 J. Biol. Chem. 1999 10.1074/jbc.274.46.32543 10 1 1 78 Humans|*Presenilin-1|*Disks Large Homolog 4 Protein|Phosphoproteins|Carrier Proteins|Nerve Tissue Proteins|Zonula Occludens-1 Protein|Protein Binding|Amino Acid Sequence|Binding Sites|Tumor Suppressor Proteins|Signal Transduction|*Transcription Factors|Yeast Two-Hybrid System 18 TESMIN 10191092 Genomics 1999 10.1006/geno.1999.5756 20 0 2 39 Humans|Male|Mice|Animals|tesmin|*Metallothionein|*Testis|Spermatogenesis|cDNA|Spermatocytes|In Situ Hybridization|Amino Acid Sequence|Meiosis|Base Sequence|Blotting, Northern|Cloning, Molecular|Chromosome Mapping|CRIP1 protein, human|Carrier Proteins|Infertility, Male|Gene Expression Regulation, Developmental|LIM Domain Proteins 18 CPXM2 9809751 DNA Cell Biol. 1998 10.1089/dna.1998.17.897 8 1 0 18 Humans|Mice|Animals|*DNA, Complementary|*mRNA|Amino Acid Sequence|Base Sequence|Blotting, Northern|Carboxypeptidases|Cloning, Molecular|Proteins|Sequence Homology, Amino Acid|In Situ Hybridization|Binding Protein|Peptide, Signal|*Protein Processing, Post-Translational|*Proteomics|Sequence Analysis, DNA 18 GALK2 9603808 Appl. Environ. Microbiol. 1998 PMC106272 15 0 0 63 *Lactobacillus casei|Escherichia coli|Galactokinase|UDPgalactose 4-Epimerase|Galactose-1-Phosphate Uridyltransferase|aldose 1-epimerase|Carbohydrate Epimerases|Operon|Base Sequence|Galactose|Genes, Bacterial|Cloning, Molecular|Amino Acid Sequence|Transcription, Genetic|Plasmid 18 LMLN 9699567 Invest. Ophthalmol. Vis. Sci. 1998 0 0 0 98 *Nystagmus, Pathologic|Saccades|Eye Movements 18 DIRAS1 9070656 Oncogene 1997 10.1038/sj.onc.1200925 2 0 0 155 Humans|*Glioblastoma|Glioma|Brain Neoplasms|*Downregulation|Astrocytoma|*Proteins|Amino Acid Sequence|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Base Sequence|DNA, Neoplasm|cDNA|Cloning, Molecular|Sequence Homology, Amino Acid|mRNA|Upregulation 18 gpr19 8830667 FEBS Lett. 1996 10.1016/0014-5793(96)00901-5 3 0 1 4 Humans|Animals|Rats|ORF74 protein, Human herpesvirus 8|*Receptors, Chemokine|cDNA|Receptors, Cell Surface|Receptors, G-Protein-Coupled|Cloning, Molecular|GTP-Binding Proteins|Chromosome Mapping|Amino Acid Sequence|Blotting, Northern|In Situ Hybridization|*Brain|Gene Expression|Nerve Tissue Proteins|Neuropeptide Y Receptor|Sequence Homology, Amino Acid|Tissue Distribution|GPR19 protein, rat 18 LMLN 11542501 Neuroophthalmology 1995 10.3109/01658109509044600 2 0 0 98 Humans|*Nystagmus, Pathologic|*Visual Acuity|Fovea Centralis|Congenital Nystagmus|Fixation, Ocular|Eye Movements|Saccades|Vision Disorders 18 GALK2 7692254 Mutat. Res. 1993 10.1016/0165-1161(93)90145-p 10 0 0 63 *Escherichia coli|DNA Polymerase III|Escherichia coli Proteins|DNA Replication|Mutagenesis|Mutation|Allele|Genes, Bacterial|dnaQ protein, E coli 18 GALK2 8375645 Genetics 1993 PMC1205570 45 0 0 63 *Escherichia coli|DNA Polymerase III|*DNA Replication|Escherichia coli Proteins|Mutagenesis|SOS Response, Genetics|Chromosome, Bacterial|Nalidixic Acid|Mutation|Phenotype|Genes, Bacterial|Bacterial Proteins|Mutation Frequencies|dnaQ protein, E coli 18 LMLN 2082737 Nippon Ganka Gakkai Zasshi 1990 0 0 0 98 Humans|Nystagmus, Pathologic|Eye Movements|Strabismus|Electronystagmography|Fixation, Ocular|Saccades|Esotropia|Congenital Nystagmus|Exophoria 18 LMLN 3667159 Invest. Ophthalmol. Vis. Sci. 1987 4 0 0 98 Male|Humans|Child|*Dominance, Ocular|*Eye, Artificial|*Jerk Nystagmus|Fixation, Ocular|Eye Movements|Electronystagmography|Saccades|Strabismus|Esotropias 18 LMLN 3831487 Jpn. J. Ophthalmol. 1985 10 0 0 98 Humans|*Strabismus|*Nystagmus, Pathologic|Esotropia|Eye Movements|Congenital Nystagmus|Electrooculography|Visual Acuity|Syndrome 18 CAMK2N2 32320502 Synapse 2020 10.1002/syn.22158 0 0 0 46 Rats|Animals|*Long-Term Potentiation|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|*Upregulation|*mRNA|*Hippocampus|Synaptic Plasticity|Memory|Fear|Excitatory Postsynaptic Potentials|Amygdala|Phosphorylation|*Transcriptional Activation|Rats|Animals|*Long-Term Potentiation|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|*Upregulation|*mRNA|*Hippocampus|Synaptic Plasticity|Memory|Fear|Excitatory Postsynaptic Potentials|Amygdala|Phosphorylation|*Transcriptional Activation 17 CAMK2N2 32392180 Aging (Albany NY) 2020 PMC7244030 10.18632/aging.103137 0 0 0 46 Humans|*RNA, Long Noncoding|*circRNA|*Essential Hypertension|mRNA|RNA, Micro|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|*Signal Transduction|Computational Biology|*Catenins|Biomarkers|WNT3 protein, human|Wnt3 Protein|MIRN637 microRNA, human 17 CAMSAP1 32243862 Curr. Biol. 2020 PMC7239760 10.1016/j.cub.2020.03.013 0 0 0 94 Animals|*Centrioles|*Microtubules|Xenopus laevis|Cell Division|Cell Migration|Epithelium|Cell Nucleus|Cell Signaling 17 CAMSAP1 31951832 Mol. Ther. 2020 PMC7054739 10.1016/j.ymthe.2019.12.008 4 0 0 94 Humans|*Colorectal Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Upregulation|Cell Proliferation|Biomarkers, Tumor|Cell Movement|Cell Line, Tumor|RNAs, Circular|Sequencing, Next-Generation|*Colonic Neoplasms|Disease Progression|Signal Transduction|E2F1 protein, human|E2F1 Transcription Factor|MIRN328 microRNA, human 17 CFAP44 32460071 Sci. Total Environ. 2020 10.1016/j.scitotenv.2020.139233 0 0 0 10 Humans|Male|Mice|Animals|*Acrosome|*Sperm Motility|*Arsenic|*Sperm|*Spermiogenesis|Sperm Flagellum|Infertility, Male|Testes|*Flagellum|Fertility|*Proteomics|A Kinase Anchor Proteins|*Protein Processing, Post-Translational 17 CFAP44 32439377 Gene 2020 10.1016/j.gene.2020.144778 0 0 0 10 Male|Humans|Pregnancy|Female|Animals|Sheep|*Litter Size|*Goats|*Sperm Flagellum|Infertility, Male|Mutations, INDEL|*DNA Mutational Analysis|Cytoskeletal Proteins|Mutation|Genotype|Genetic Association Studies|Phenotype|Reproduction|AKAP4 protein, human|A Kinase Anchor Proteins 17 CFAP44 31932510 J. Cell. Sci. 2020 10.1242/jcs.239855 0 0 0 10 *Dyneins|*Axoneme|Cilia|Flagella|Chlamydomonas|Chlamydomonas reinhardtii|Microtubules|Kinesin|Plant Proteins 17 CFAP44 31901658 Chemosphere 2020 10.1016/j.chemosphere.2019.125772 0 0 0 10 Humans|Male|Mice|Animals|*Sperm Tail|*Testis|*Fluorides|Sperm Motility|Sperm|Spermatogenesis|Infertility, Male|AKAP4 protein, human|A Kinase Anchor Proteins|Axoneme|*Proteomics|mRNA|Mutation|DNAH1 protein, human|Dyneins|SPAG6 protein, mouse|Microtubule Proteins|SPEF2 protein, mouse 17 CPLANE1 32335874 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 10.3760/cma.j.issn.1003-9406.2020.05.004 0 0 0 15 Humans|Pregnancy|Female|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Prenatal Diagnosis|*Genetic Testing|Pedigree|Mutation|Membrane Proteins|Magnetic Resonance Imaging 19 DCLK2 32109663 Atherosclerosis 2020 10.1016/j.atherosclerosis.2020.02.005 0 0 0 159 *Prospective Studies|Cholesterol, HDL|Cardiovascular Disease|Genome-Wide Association Study|Genotype|Phenotype|Polymorphism, Single Nucleotide|Lipid Metabolism|Longevity 17 DCLK2 31919093 Haematologica 2020 10.3324/haematol.2019.228478 1 0 0 159 *DNA Methylation|*Leukemia, Lymphocytic, Chronic, B-Cell|*Retroelements|*Epigenesis, Genetic|Long Interspersed Nucleotide Elements|Alu Elements|Cell Line, Tumor 17 FAM172A 32481657 Molecules 2020 PMC7321164 10.3390/molecules25112520 0 0 0 42 Humans|*Proteomics|Cytomegalovirus|Virus Latency|Viral Proteins|Virus Replication|Host-Pathogen Interactions|Cell Line 17 FAM172A 31988090 Biol Open 2020 PMC7044457 10.1242/bio.048462 0 0 0 42 Humans|*Epithelial-Mesenchymal Transition|*Pancreatic Cancer|Cadherins|Cell Movement|Vimentin|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Immunohistochemistry|FAM172A protein, human|Proteins 17 FAM172A 31915594 Anal Cell Pathol (Amst) 2020 PMC6930761 10.1155/2019/5901083 0 0 0 42 *Hep G2 Cells|Carcinoma, Hepatocellular|Liver Neoplasms|*Proteins|Cell Proliferation|Cell Line, Tumor|Signal Transduction 17 FANK1 32398127 Clin Epigenetics 2020 PMC7218560 10.1186/s13148-020-00846-0 0 0 0 22 Humans|*Atherosclerosis|*Promoter Regions, Genetic|Plaques, Atherosclerotic|DNA Methylation|Epigenesis, Genetic|*Epigenetic|*Protein Processing, Post-Translational|Monocytes|*Biomarkers|ALOX12 protein, human|Arachidonate 12-Lipoxygenase 17 FANK1 32392195 Mol. Biol. (Mosk.) 2020 10.31857/S002689842002007X 0 0 0 22 Humans|*Chromatin|*rDNA|Epigenesis, Genetic|HEK293 Cells|Chromatin Assembly and Disassembly|Chromosome|Transcription Factors|Transcription, Genetic|Genes, Regulator|Cell Differentiation|Heat Shock|BCCIP protein, human|Calcium-Binding Proteins|Nuclear Proteins|Cell Cycle Proteins|Fank1 protein, human|DNA-Binding Proteins 17 IPO11 32218703 Int J Med Sci 2020 PMC7085267 10.7150/ijms.40697 0 0 0 123 Humans|Female|Pregnancy|Mice|Animals|*Embryonic Development|Karyopherins|Embryo, Mammalian|Transport, Nucleo-cytoplasmic|Gene Expression Regulation, Developmental|Phenotypes 17 IPO11 32183388 Cancers (Basel) 2020 PMC7140034 10.3390/cancers12030692 0 0 0 123 *Proteome|*Extracellular Vesicles|miRNAs|*Hypoxia|*Secretory Vesicles|Cell Line, Tumor|Cell Communication|*Acclimatization|Melanoma|Tumor Microenvironment 17 MIR503 32311422 Mol. Cell. Endocrinol. 2020 10.1016/j.mce.2020.110819 1 0 0 0 Male|Female|Animals|Humans|*RNA, Long Noncoding|*Primates|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Splicing, Alternative RNA|Exon|Cell Line, Tumor|Genomics|MIRN503 microRNA, human|MicroRNAs 17 MIR503 32184661 Cancer Manag Res 2020 PMC7060770 10.2147/CMAR.S225489 0 0 0 0 Humans|Female|*RNA, Long Noncoding|CASP3 protein, human|*Caspase 3|Neoplasm Recurrence, Local|*Carcinoma, Squamous Cell|*Uterine Cervical Neoplasms|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Cell Line, Tumor|*Drug Resistance|MIRN155 microRNA, human|MIRN503 microRNA, human 17 MYLK3 32655616 Front Genet 2020 PMC7325882 10.3389/fgene.2020.00569 0 0 0 162 Sheep|Animals|*Quantitative Trait Loci|*DNA Copy Number Variations|Genome-Wide Association Study|*Phenotype|Chromosome Mapping|Quantitative Trait, Heritable|Genotype|Genetic Association Studies|Molecular Sequence Annotation|Polymorphism, Single Nucleotide 17 MYLK3 32213617 Life Sci Alliance 2020 PMC7103425 10.26508/lsa.201900593 0 0 0 162 Animals|Mice|*Mice, Inbred C57BL|Transhydrogenase, Nicotinamide Nucleotide|Mice, Inbred Strains|Phenotype|Genotype|Disease Models, Animal 17 NAGPA 32109365 Structure 2020 10.1016/j.str.2020.02.001 0 0 0 19 mannose-6-phosphate|N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase|Mannosephosphates|*Phosphoric Diester Hydrolases|Hydrolases|Receptor, IGF Type 2|Mannose|Acetylglucosamine|Catalytic Domain|Polysaccharides 17 NAGPA 31948430 BMC Cancer 2020 PMC6966810 10.1186/s12885-020-6515-2 0 0 0 19 *RNA, Circular|*Multiple Myeloma|*Prognosis|MicroRNAs|Biomarkers 17 RAB6C 32257197 Mol Clin Oncol 2020 PMC7087479 10.3892/mco.2020.2014 0 0 0 56 Humans|*Tamoxifen|*Receptors, Progesterone|Receptors, Estrogen|Antineoplastic Agents, Hormonal|Chemotherapy, Adjuvant|Disease-Free Survival|Neoplasm Recurrence, Local|Treatment Outcome|Estrogens 17 RAB6C 31897114 Oncol Lett 2020 PMC6923975 10.3892/ol.2019.11109 1 0 0 56 *Receptors, Progesterone|*Prognosis|Receptors, Estrogen|Receptor, ErbB-2|Chemotherapy, Adjuvant|Biomarkers, Tumor|Estrogens 17 RAPGEF5 32277301 Clin. 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Nephrol. 2020 10.1007/s10157-020-01884-x 0 0 0 1596 Humans|*Genome-Wide Association Study|*Albuminuria|Japan|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian|Genetic Loci|Genotype|Chronic Kidney Disease|Risk Factor 17 rnf113a 32152280 Nat Commun 2020 PMC7062854 10.1038/s41467-020-15003-7 0 0 0 51 *Spliceosomes|*Trichothiodystrophy Syndromes|*Cell Survival|MCL1 protein, human|Myeloid Cell Leukemia Sequence 1 Protein|*DNA Damage|Cisplatin|Antineoplastic Agents|Proto-Oncogene Proteins c-bcl-2|Apoptosis|Proto-Oncogene Proteins c-akt|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|*X-Linked Gene|Phosphorylation|Cell Line, Tumor|RNA Splicing|Signal Transduction 17 rnf113a 32081867 Sci Rep 2020 PMC7035424 10.1038/s41598-020-59922-3 0 0 0 51 Humans|*Autism Spectrum Disorder|*Exome|*DNA Copy Number Variations|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Pedigree|Cohort Studies|Neurodevelopmental Disorders|CNTNAP2 protein, human|Membrane Proteins|Nerve Tissue Proteins|VPS13B protein, human|Vesicular Transport Proteins|RNF113A protein, human|DNA-Binding Proteins|WWOX protein, human|WW Domain-Containing Oxidoreductase 17 rnf113a 31934207 Int J Clin Exp Pathol 2020 PMC6949850 0 0 0 51 Humans|Female|*Carcinogenesis|TP53 protein, human|TP53 Protein|Cervical Cancer|Neoplasm Invasiveness|Apoptosis|Cell Movement|Cell Proliferation|Cell Line, Tumor|HeLa Cells|Gene Expression Regulation, Neoplastic|RNA, Small Interfering|Up-Regulation|RNF113A protein, human|DNA-Binding Proteins 17 STXBP6 32467162 Proc. 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Physiol., Cell Physiol. 2020 10.1152/ajpcell.00485.2019 2 0 0 1214 Humans|desmuslin|*Intermediate Filament Proteins|*Myopathies|Desmin|Muscle Proteins|*Heart 17 TECPR2 32559424 Mol. Cell 2020 10.1016/j.molcel.2020.04.017 0 0 0 99 Calcium Channels|Calcium Signaling|Calcium 18 TECPR2 32253221 J Immunother Cancer 2020 PMC7174067 10.1136/jitc-2020-000802 0 0 0 99 Cytotoxicity, Immunologic|Natural Killer Cells|CD8-Positive T-Lymphocytes|*Cell Death 18 TECPR2 32209221 J Clin Sleep Med 2020 10.5664/jcsm.8434 0 0 0 99 Humans|Child|Female|Child, Preschool|*Sleep Apnea, Central|*Mutation|Nerve Tissue Proteins|Carrier Proteins|Respiration|Autophagy|Sleep|Respiratory Insufficiency|TECPR2 protein, human 18 TECPR2 32122540 Meth. Enzymol. 2020 10.1016/bs.mie.2019.04.014 0 0 0 99 Humans|Mice|Animals|*BALB C Mice|CD8-Positive T-Lymphocytes|Combined Modality Therapy|Cell Line, Tumor|Interferon-gamma 18 TEFM 31934014 Int J Clin Exp Pathol 2020 PMC6947131 0 0 0 45 Humans|*Glioma|Brain Neoplasms|Prognosis|Immunohistochemistry|Kaplan-Meier Estimate|Biomarkers, Tumor|mRNA|*Neoplastic Processes|Up-Regulation|Western Blot|Brain 17 TRIM47 32603762 Mol. Cell. Probes 2020 10.1016/j.mcp.2020.101623 0 0 0 68 *Glioma|*Wnt Pathway|*Cell Proliferation|Cell Migration|Neoplasm Invasiveness|*Catenins|Epithelial-Mesenchymal Transition|Cell Line, Tumor|beta Catenin|CDH1 protein, human|N-Cadherin|Gene Expression Regulation, Neoplastic|Oncogenesis|*Neoplastic Processes|Antigens, CD 17 TRIM47 32502539 Life Sci. 2020 10.1016/j.lfs.2020.117893 0 0 0 68 Humans|*Melitten|*Fibroblast|*Fibrosis|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|*Lung|Cell Movement|Cell Proliferation|Nuclear Proteins|Signal Transduction|Carrier Proteins|TRIM47 protein, human 17 TRIM47 31981573 Chem. Biol. Interact. 2020 10.1016/j.cbi.2020.108960 1 0 0 68 Humans|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Oncogenesis|*Cell Transformation, Neoplastic|Epithelial-Mesenchymal Transition|Cell Proliferation|Neoplasm Invasiveness|Signal Transduction|Cell Movement|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Cell Line, Tumor|Biomarkers, Tumor|Gene Knockdown Techniques|IGF1 protein, human|Insulin-Like Growth Factor I|*Disease Progression|MCF-7 Cells 17 ZNF146 32267586 FASEB J. 2020 10.1096/fj.201901926R 0 0 0 42 CLSPN protein, human|*Adaptor Proteins, Signal Transducing|DNA Replication|Cell Cycle Proteins|DNA Repair|Checkpoint Kinase 1|Cell Cycle|Protein Kinases|*Chromosome Structures|Binding Proteins 17 ZNF146 32190005 Cancer Cell Int. 2020 PMC7071687 10.1186/s12935-020-1122-5 0 0 0 42 Humans|*Stomach Neoplasms|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Disease Progression|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Neoplastic Processes|Cell Line, Tumor|*Stomach|Cell Movement|Tumorigenesis 17 BTBD7 31886230 Biomed Res Int 2019 PMC6900955 10.1155/2019/5937635 4 0 0 55 Humans|*Epithelial-Mesenchymal Transition|CDH1 protein, human|*E Cadherin|*Lung Cancer|*Antigens, CD|*Downregulation|Vimentin|Snail Family Transcription Factors|A549 Cells|Gene Expression Regulation, Neoplastic|Cell Movement|FN1 protein, human|Fibronectin|Transforming Growth Factor beta1|Cell Line, Tumor|BTBD7 protein, human|Neoplasm Proteins 17 BTBD7 31303496 EBioMedicine 2019 PMC6710852 10.1016/j.ebiom.2019.06.044 2 2 0 55 Humans|*Beauty|Gene Expression Regulation, Neoplastic|MicroRNAs|Epithelial-Mesenchymal Transition|Colorectal Neoplasms|Cell Line, Tumor|Cell Movement|Cell Proliferation|Signal Transduction|*Colonic Neoplasms|BTBD7 protein, human|Neoplasm Proteins 17 CAMSAP1 31748546 Nat Commun 2019 PMC6868217 10.1038/s41467-019-13247-6 2 0 0 94 Humans|Cryoelectron Microscopy|*Microtubules|Tubulin|Microtubule-Associated Proteins|Protein Binding|Molecular Conformation|Models, Molecular 17 CAMSAP1 31284878 BMC Mol Cell Biol 2019 PMC6469034 10.1186/s12860-019-0189-0 0 0 0 94 Animals|*Drosophila|*Mitosis|Mitotic Spindle|Microtubules|Drosophila Proteins|Microtubule-Associated Proteins|Kinesin|Drosophila melanogaster|Chromosome Segregation|Microscopy, Fluorescence|Green Fluorescent Proteins|Polymerization|patronin protein, Drosophila 17 CFAP44 30904354 Reprod. Biomed. Online 2019 10.1016/j.rbmo.2018.12.037 3 0 0 10 Humans|Male|*Sperm Flagellum|*Infertility, Male|*Mutations|Spermatozoa|Microtubule Proteins|Whole Exome Sequencing|*Multiple Abnormalities|Cytoskeletal Proteins|Flagella|AKAP4 protein, human|A Kinase Anchor Proteins|DNAH1 protein, human|Dyneins 17 CFAP44 30867909 Basic Clin Androl 2019 PMC6398242 10.1186/s12610-019-0083-9 2 5 0 10 Humans|Male|*Sperm Tail|*Infertility, Male|Sperm|Asthenozoospermia|Flagella|Whole Exome Sequencing|Cytoskeletal Proteins|Mutations|Cohort Studies 17 CFAP44 30686508 Am. J. Hum. Genet. 2019 PMC6372258 10.1016/j.ajhg.2018.12.013 9 0 0 10 Male|Humans|Mice|Animals|*Sperm Tail|*Teratozoospermia, Astheno|Infertility, Male|Sperm|*Alleles|Axonemes|*Mutations|Sequencing, Whole Exome|Homozygote|Flagella|Phenotype|Cytoskeletal Proteins|Multiple Abnormalities|DNAH1 protein, human|Dyneins|SPAG6 protein, mouse|Microtubule Proteins|SPEF2 protein, mouse 17 CPLANE1 31004438 Ann. Neurol. 2019 10.1002/ana.25491 0 1 0 15 Humans|*Neurogenesis|*Mitosis|Microtubule-Associated Proteins|*Ciliopathy|Dyneins|1-Alkyl-2-acetylglycerophosphocholine Esterase|Neurons|Cell Movement|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Carrier Proteins|Cerebral Cortex|Cells, Cultured|Cerebellum|Eye Abnormalities|Abnormalities, Multiple|Retina 19 DCLK2 31583809 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2019 10.1002/ajmg.b.32763 2 0 0 159 *Genome-Wide Association Study|*Stress Disorders, Post-Traumatic|COMT protein, human|Catechol O-Methyltransferase|Depressive Disorder, Major|*Depression|Genetic Predisposition to Disease|SLC6A4 protein, human|Serotonin Plasma Membrane Transport Proteins|Resilience, Psychological|Adaptation, Psychological 17 DCLK2 31578829 Mol Genet Genomic Med 2019 PMC6978259 10.1002/mgg3.992 1 0 0 159 Child|Humans|Male|*Microcephaly|*Exome|*Corpus Callosum|Partial agenesis of corpus callosum|*Agenesis of Corpus Callosum|*Whole Exome Sequencing|*Epilepsy|Hypotonia|Developmental Disabilities|Mutation 17 DCLK2 31081985 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2019 PMC6551278 10.1002/ajmg.b.32730 1 0 0 159 Humans|*Military Personnel|*Resilience, Psychological|*Genome-Wide Association Study|Stress Disorders, Post-Traumatic|Genetic Predisposition to Disease|Anxiety Disorders|Polymorphism, Single Nucleotide|Depressive Disorder, Major|Risk Factors 17 FAM172A 31026301 PLoS ONE 2019 PMC6485638 10.1371/journal.pone.0215745 0 0 0 42 Humans|Child|Female|Pregnancy|*DNA Methylation|CpG Islands|*Placenta|Epigenesis, Genetic|Epigenetic|Maternal Exposure|Birth Weight|Genome-Wide Association Study|Smoking|Night Shift Work|Tobacco Smoking|Linear Models|Rhode Island|CLEC16A protein, human|Monosaccharide Transport Proteins|Lectins, C-Type|FAM172A protein, human|Proteins 17 FANK1 31373619 Biol. Reprod. 2019 10.1093/biolre/ioz154 2 0 0 22 Humans|Male|Mice|Animals|*COP9 Signalosome Complex|*Acrosome|*Cell Survival|*Spermatogenesis|Spermatids|Spermatocytes|Testis|Sperm|Infertility, Male|Sperm Number|Mice, Knockout|Signal Pathways|Ubiquitination|IFT20 protein, human|Carrier Proteins|Ift20 protein, mouse 17 FANK1 31086747 PeerJ 2019 PMC6486812 10.7717/peerj.6827 0 0 0 22 Male|*Spermatogenesis|Testis|Epididymis|Spermatozoa 17 FANK1 30867990 PeerJ 2019 PMC6410691 10.7717/peerj.6557 1 4 0 22 17 IPO11 31881079 J. Cell Biol. 2019 PMC7041691 10.1083/jcb.201903017 2 0 0 123 Humans|*Active Transport, Cell Nucleus|*Colorectal Cancers|Wnt Signaling Pathway|beta Catenin|*Catenins|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Tumor Suppressor Proteins|Cell Nucleus|Apoptosis|Cytoplasm|Nuclear Protein|IPO11 protein, human|beta Karyopherins 17 IPO11 31339356 Am. J. Respir. Crit. Care Med. 2019 PMC6884045 10.1164/rccm.201903-0511OC 4 1 0 123 17 MIR486 31661131 Mol Med Rep 2019 10.3892/mmr.2019.10769 0 2 0 0 Humans|*Carcinoma, Renal Cell|*Prognosis|*Oncogene|Kidney Neoplasms|MicroRNAs|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Movement|Upregulation|Cell Line, Tumor|Biomarkers, Tumor|Flow Cytometry|MIRN486 microRNA, human 17 MIR486 30710084 Nat Commun 2019 PMC6358625 10.1038/s41467-019-08492-8 2 0 0 0 Animals|*Weight Loss|Genome-Wide Association Study|Drosophila melanogaster|Canada|Homeodomain Proteins|Transcription Factors|Drosophila Proteins|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Obesity|Body Mass Index 17 MIR503 31822509 J. Biol. Chem. 2019 PMC6996892 10.1074/jbc.RA119.008742 1 6 0 0 Humans|Adult|CCND1 protein, human|*Cyclin D1|*RNA, Micro|*Protein-Arginine N-Methyltransferases|*Genes, myc|histone deacetylase 3|Histone Deacetylases|*Transcription Factors|*Downregulation|HDAC2 protein, human|Histone Deacetylase 2|Lymphoma|Histones|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Lymphoma, Non-Hodgkin|Cell Line, Tumor|*Genes, Tumor Suppressor 17 MIR503 31467616 Dis. Markers 2019 PMC6701315 10.1155/2019/4976845 0 10 0 0 Pregnancy|Humans|Female|*Trophoblasts|*RNA, Long Noncoding|*Pre-Eclampsia|*Matrix Metalloproteinases|*Cell Proliferation|Cell Movement|Placenta|Apoptosis|Down-Regulation|Cell Line 17 MIR503 31186710 Oncol Lett 2019 PMC6507402 10.3892/ol.2019.10191 3 1 0 0 *RNA, Long Noncoding|*Carcinoma, Non-Small-Cell Lung|XAV939|*Lung Neoplasms|*Sequencing, RNA|miRNA|*Heterocyclic Compounds, 3-Ring|Gene Regulatory Networks|mRNA|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|*Whole Exome Sequencing|Computational Biology|Protein Interaction Maps 17 MIR503 31062436 J. Cell. Mol. Med. 2019 PMC6584514 10.1111/jcmm.14344 6 2 0 0 Humans|*RNA, Long Noncoding|*Cell Migration|*Triple-Negative Breast Cancer|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Lymphatic Metastasis|OLFM4 protein, human|Granulocyte Colony-Stimulating Factor|MIRN103 microRNA, human|MIRN503 microRNA, human 17 MIR503 30672010 J. Cell. Biochem. 2019 10.1002/jcb.28373 3 12 0 0 Mice|Animals|*RNA, Long Noncoding|*Epithelial-Mesenchymal Transition|*Urinary Bladder Neoplasms|Mice, Nude|Neoplasm Recurrence, Local|*Cell Proliferation|*Genes, Tumor Suppressor|Cell Movement|CDH1 protein, human|N-Cadherin|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Neoplastic Processes|Downregulation|Lymphatic Metastasis|Biomarkers, Tumor|Cell Cycle|Signal Transduction 17 MYLK3 31566189 J. Physiol. Pharmacol. 2019 10.26402/jpp.2019.3.10 0 3 0 162 Mice|Animals|bisphenol A|*Mouse Embryonic Stem Cells|*Myocytes, Cardiac|*Calcium Signaling|*Benzhydryl Compounds|octylphenol|*Phenols|Endocrine Disrupting Chemicals|progesterone receptor B|Progesterone Receptor|Estrogens|*Cell Differentiation|Progesterone|Calcium Channel|Cardiac Muscle|*Organogenesis 17 MYLK3 31244672 Front Physiol 2019 PMC6563786 10.3389/fphys.2019.00696 1 0 0 162 17 MYLK3 30690923 ESC Heart Fail 2019 PMC6437445 10.1002/ehf2.12410 4 8 0 162 Humans|*Myosin-Light-Chain Kinase|Familial dilated cardiomyopathy|*Cardiomyopathy, Dilated|*Phosphorylation|Cardiac Myosins|Myosin Light Chains|Sarcomere|Myocardial Contraction|Cardiomyocyte|Myocardium|*Mutations|Heart Ventricles 17 MYO3B 31002663 PLoS Biol. 2019 PMC6493769 10.1371/journal.pbio.3000235 1 0 0 42 Animals|Zebrafish|*Morphogenesis|Spinal Cord|Zebrafish Proteins|Sensory Neurons|Actin|Cell Differentiation 17 NAGPA 31212009 Food Chem. 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Patterns 2019 10.1016/j.gep.2019.119057 0 0 0 1596 Animals|Mice|Humans|*Guanine Nucleotide Exchange Factor|RASGRF1 protein, human|*ras-GRF1|ras Guanine Nucleotide Exchange Factors|GTPase-Activating Proteins|Xenopus|*Mammalian Embryos|Amino Acid Sequence|GTPases|Wnt Signaling Pathway 17 RAPGEF5 31028805 Life Sci. 2019 10.1016/j.lfs.2019.04.045 0 2 0 1596 Humans|*Anemia, Aplastic|miRNA|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Upregulation|Case-Control Studies 17 RAPGEF5 30785065 Mol Ther Nucleic Acids 2019 PMC6379567 10.1016/j.omtn.2019.01.003 8 23 0 1596 *Thyroid Gland|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|Thyroid Cancer, Papillary|Thyroid Cancer|Cell Proliferation|Carcinoma, Papillary|Neoplasm Invasiveness|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|RNA, Long Noncoding|Upregulation|3' UTR|Cell Line, Tumor|Downregulation|Apoptosis|Tumorigenesis 17 rnf113a 31880405 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61450 0 0 0 51 Male|Humans|Female|Child|*Trichothiodystrophy Syndromes|DNA-Binding Proteins|Hair Diseases|Phenotype|*Genes, X-Linked|Mutations|RNF113A protein, human 17 rnf113a 31793730 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61384 0 1 0 51 Humans|Trichothiodystrophy|Microcephaly|Partial agenesis of corpus callosum|Agenesis of Corpus Callosum|Exome|Intellectual Disability|Whole Exome Sequencing|DNA-Binding Proteins|RNA Splicing|Pedigree|DNA Repair|Genes, X-Linked|Amino Acid Sequence|Mutation|RNF113A protein, human 17 rnf113a 31374204 Am. J. Hum. Genet. 2019 PMC6698936 10.1016/j.ajhg.2019.06.017 1 1 0 51 Humans|*tRNA Synthetase|Trichothiodystrophy|Transcription Factor TFIIH|*Hair Diseases|transcription factor TFIIE|Nucleotide Excision Repair|*Phenotype|*Alleles|*Mutations|Ichthyosis|DNA Helicases|Transcription, Genetic|UV Light|Hair|RNF113A protein, human|DNA-Binding Proteins|MPLKIP protein, human|Adaptor Proteins, Signal Transducing 17 rnf113a 31326362 DNA Repair (Amst.) 2019 10.1016/j.dnarep.2019.102663 0 1 0 51 *DNA Repair|*Alkylation|DNA Damage|DNA Repair Enzymes|Trichothiodystrophy|DNA Helicases|DNA Adducts|Pyrimidine Dimers|AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase|DNA-Binding Proteins|DNA Replication|Chromatin Assembly and Disassembly 17 STXBP6 31099751 Elife 2019 PMC6557626 10.7554/eLife.41711 6 0 0 29 *Insulin|Neurodegenerative Diseases|*Exocytosis|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|*Insulin, Regular, Human|Insulin-Secreting Cells|Insulin Secretion|Cyclic AMP|Guanine Nucleotide Exchange Factors|Signal Transduction|Carrier Proteins 18 SYNM 31602316 NPJ Genom Med 2019 PMC6779875 10.1038/s41525-019-0098-3 6 0 0 1214 *DNA Copy Number Variations|Autism Spectrum Disorder|*Neurodevelopmental Disorders|Genome-Wide Association Study|Attention Deficit-Hyperactivity Disorder|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Schizophrenia|*Genomics|Obsessive Compulsive Disorder 17 SYNM 31461342 Am. J. Physiol., Cell Physiol. 2019 10.1152/ajpcell.00047.2019 1 4 0 1214 Humans|myocardin|desmuslin|*Intermediate Filaments|*Trans-Activators|*Nuclear Proteins|*Intermediate Filament Proteins|Serum Response Factor|Myocytes, Smooth Muscle|Transcription Factors|Cell Differentiation|Muscle, Smooth, Vascular|Microfilament Proteins|Cells, Cultured|Promoter Regions, Genetic|RNA, Messenger 17 SYNM 30603658 J Med Imaging (Bellingham) 2019 PMC6303840 10.1117/1.JMI.6.3.031403 0 0 0 1214 Humans|*Digital Mammography|*Early Detection of Cancer|*Screening|Radiographic Image Enhancement|Radiographic Image Interpretation, Computer-Assisted|Retrospective Studies|*Diagnostic Tests, Routine|*Mental Recall|*Research|Artefact|Physical Examination|Record 17 TECPR2 31730196 Genome Biol Evol 2019 PMC7145703 10.1093/gbe/evz250 1 0 0 99 Animals|Echolocation|Bats|*Hearing|*Comparative Genomics|*Cochlea|Whales|Evolution, Molecular|Phylogeny|Selection, Genetic|*Hearing Tests|Profile, Gene Expression 18 TECPR2 31621692 Med. 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Monit. 2019 PMC6820336 10.12659/MSM.917082 2 0 0 99 Humans|*Computational Biology|*Prognosis|Networks, Gene|Protein Interaction Maps|Gene Ontology|Gene Expression Regulation, Neoplastic|MicroRNAs|Gene Expression Profiling|Liver Neoplasms|RNA, Messenger|Upregulation|Databases, Genetic|Downregulation|Transcriptome|Biomarkers, Tumor|*Melanoma|Software|Kaplan-Meier Survival Curves 18 TECPR2 30681437 Alzheimer Dis Assoc Disord 2019 10.1097/WAD.0000000000000294 0 0 0 99 *Neuropathology|*Brain|Alzheimer Disease|*Healthy Ageing|Nerve Tissue Proteins|*Sequencing, Whole Genome|Disease Progression|*Nervous System Diseases 18 TEFM 31703719 Ital J Pediatr 2019 PMC6839219 10.1186/s13052-019-0718-7 0 0 0 45 Humans|*Neurofibromatosis 1|NF1 Microdeletion Syndrome|Neurofibromatoses|Chromosome Deletion|Craniofacial Abnormalities|Intellectual Disability|Learning Disabilities|Genes, Neurofibromatosis 1|Karyotyping|In Situ Hybridization, Fluorescence 17 TEFM 31309618 Protein Sci. 2019 PMC6699104 10.1002/pro.3688 3 0 0 45 Humans|Animals|*Transcription, Genetic|Mitochondrial Proteins|Transcription Factors|Mitochondria|DNA-Binding Proteins|*Mammals|DNA, Mitochondrial|Gene Expression Regulation|Mitochondrial Diseases|Methyltransferases 17 TEFM 31036713 EMBO Rep. 2019 PMC6549021 10.15252/embr.201948101 4 4 0 45 *Mitochondria|DNA, Mitochondrial|Transcription, Genetic|Mitochondrial Proteins|Transcription Factors|DNA-Directed RNA Polymerases|Oxidative Phosphorylation|DNA Replication|3'-(1-butylphosphoryl)adenosine|*Complement Factor B|RNA 17 TRHDE 31354623 Front Endocrinol (Lausanne) 2019 PMC6637657 10.3389/fendo.2019.00445 2 0 0 27 Male|Female|Rats|Animals|*Thyroid Gland|*Rats, Wistar|*Maternal Deprivation|Sexual Maturation|Hypothalamus|*Sex Dimorphisms|Thyrotropin-Releasing Hormone|Thyroid Hormones|Leptin|Hypothalamo-Hypophyseal System|Obesity|Diet, High-Fat 17 TRHDE 31297093 Front Endocrinol (Lausanne) 2019 PMC6607407 10.3389/fendo.2019.00418 0 9 0 27 Male|Female|Rats|Animals|*Thyroid Gland|*Rats, Wistar|Thyrotropin-Releasing Hormone|Paraventricular Nucleus, Hypothalamic|Hypothalamo-Hypophyseal System|*Sex Dimorphisms|Corticosterone|*Fat, White|Restraint, Physical|mRNA 17 TRHDE 31119790 J. Cell. Biochem. 2019 10.1002/jcb.29029 4 1 0 27 *RNA, Long Noncoding|*miRNA|*Lung Cancer|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|*Disease Progression|Cell Line, Tumor|Apoptosis|Signal Transduction|Xenograft Model Antitumor Assays 17 TRHDE 31119684 Genes Genomics 2019 10.1007/s13258-019-00820-y 1 0 0 27 Sheep|Animals|*Altitude|*Genome|*Genomics|Selection, Genetic|Genetics, Population|Adaptation, Physiological|Polymorphism, Single Nucleotide 17 TRIM47 31178138 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.05.065 0 0 0 68 Humans|Animals|Rats|*Ischemia-Reperfusion Injury|*Apoptosis|*Inflammation|Brain Ischemia|CASP3 protein, human|Caspase 3|Nuclear Factor-Kappab|Middle Cerebral Artery Occlusion|Signal Transduction|Stroke|NOS2 protein, human|Inducible Nitric Oxide Synthase|Toll-Like Receptor 4|Neuroprotective Agents|Tumor Necrosis Factor-alpha|Neurons|Rats, Sprague-Dawley|Brain 17 TRIM47 30979374 J. Exp. Clin. Cancer Res. 2019 PMC6461818 10.1186/s13046-019-1143-x 0 8 0 68 *Colorectal Cancer|SMAD4 protein, human|*Smad4 Protein|*Up-Regulation|*Ubiquitination|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Cell Movement|Biomarkers, Tumor|Cell Line, Tumor|Cell Proliferation|*Transcriptional Activation|*Colonic Neoplasms|Heterografts 17 ZNF146 31703168 Circ Genom Precis Med 2019 10.1161/CIRCGEN.118.002489 0 0 0 42 *Heart Failure|*Echocardiography|Stroke Volume|Ventricular Function, Left|Heart Ventricles|*Framingham Heart Study|Heart 17 ATP5G3 30539817 Neural Regen Res 2018 PMC6334607 10.4103/1673-5374.245474 1 2 0 115 Animals|Rats|*Glucose|*Oxygen|*Ethanol|*Cerebellum|Central Nervous System Depressants|*Cytoplasmic Granules|Neurons|Hypoxia|Cells, Cultured|Animals, Newborn|*Energy Metabolism|Cell Survival|Adenosine Triphosphate|Nitric Oxide Synthase|Cell Death 17 BTBD7 31938244 Int J Clin Exp Pathol 2018 PMC6958179 0 0 0 55 17 BTBD7 29366608 Oral Surg Oral Med Oral Pathol Oral Radiol 2018 10.1016/j.oooo.2017.12.004 0 3 0 55 *Carcinoma, Adenoid Cystic|FN1 protein, human|*Fibronectins|*BTB-POZ Domain|Salivary Gland Neoplasms|Neoplasm Invasiveness|Cell Movement|Cell Line, Tumor|Cell Proliferation 17 C2orf40 29886034 Gene 2018 10.1016/j.gene.2018.06.019 4 0 0 0 Humans|*Cardiomyopathy, Dilated|Homozygote|Pakistan|Sequence Deletion|Exomes|*Mutation|Allele Frequency|Pedigree|Genetic Association Studies|Mutation, Missense|Frameshift Mutation|Codon, Nonsense|Base Sequence|RTKN2 protein, human|Intracellular Signaling Peptides and Proteins|MYOM3 protein, human|Connectin 17 C2orf40 29458411 Alzheimers Res Ther 2018 PMC5819208 10.1186/s13195-018-0349-z 1 5 0 0 *Alzheimer Disease|Genome-Wide Association Study|Neurofibrillary Tangles|*Neuropathology|Plaque, Amyloid|Cerebral Amyloid Angiopathy|Amyloid beta-Peptides|Brain|*Nervous System Diseases 17 CAMK2N2 30559663 Front Pharmacol 2018 PMC6287013 10.3389/fphar.2018.01373 0 0 0 46 Animals|Rats|*N-Methyl-3,4-methylenedioxyamphetamine|VDR protein, human|*Receptors, Calcitriol|*Down-Regulation|*Hippocampus|Gene Expression Regulation|Serotonin|Cognition|Gene Expression 17 CAMK2N2 29680575 J Psychiatr Res 2018 10.1016/j.jpsychires.2018.04.012 2 0 0 46 Humans|*Body Mass Index|reelin protein|*Cell Adhesion Molecules, Neuronal|*Serine Endopeptidases|*Extracellular Matrix Proteins|*Nerve Tissue Proteins|*Schizophrenia|*Gene Expression|Hippocampus|Prefrontal Cortex|mRNA|Neurons|Brain 17 CAMSAP1 30210331 Front Aging Neurosci 2018 PMC6119720 10.3389/fnagi.2018.00259 2 4 0 94 Adult|Humans|Animals|Mice|Neurodegenerative Diseases|Gene Modules|Gene Expression Profiling|*Cortex, Prefrontal|Biomarkers|Brain 17 CAMSAP1 29538313 Int J Mol Sci 2018 PMC5877712 10.3390/ijms19030851 4 11 0 94 Humans|*Carcinoma, Hepatocellular|*Liver Cancer|*Argonaute Proteins|MicroRNAs|Gene Expression Regulation, Neoplastic|3' Untranslated Region|RNA Interference|*Liver|Messenger RNA|Cell Line, Tumor|Cell Proliferation|Transcriptome|Immunoprecipitation|Carcinogenesis|*Species Specificity|DDX1 protein, human|DEAD-box RNA Helicases|MIRN21 microRNA, human 17 CFAP44 30415212 J. Med. Genet. 2018 10.1136/jmedgenet-2018-105486 6 0 0 10 Humans|Male|Sperm Motility|*Homozygote|Infertility, Male|Sperm Tail|Spermatozoa|Spermatozoa, Abnormal|Flagella|Whole Exome Sequencing|Cytoskeletal Proteins|Mutation 17 CFAP44 30251428 Andrologia 2018 10.1111/and.13151 2 0 0 10 Humans|Male|Pregnancy|Female|*Sperm Injections, Intracytoplasmic|*Pregnancy Outcome|Retrospective Studies|*Sperm Flagellum|Infertility, Male|Spermatozoa|Flagella|Teratozoospermia|*Mutations|*Multiple Abnormalities|Microtubule Proteins|Whole Exome Sequencing|Cytoskeletal Proteins|DNAH1 protein, human|Dyneins 17 CFAP44 30137358 Hum. Reprod. 2018 10.1093/humrep/dey264 10 1 0 10 Humans|Male|*Whole Exome Sequencing|*Sperm Flagellum|Infertility, Male|Spermatozoa|*Mutations|*Multiple Abnormalities|Microtubule Proteins|Cytoskeletal Proteins 17 CFAP44 30122540 Am. J. Hum. Genet. 2018 PMC6128304 10.1016/j.ajhg.2018.07.014 6 0 0 10 Humans|Male|*Sperm Tail|*Homozygote|Sequence Deletion|*Infertility, Male|Axoneme|WDR66 protein, human|*Calcium-Binding Proteins|Spermatozoa|Sequencing, Whole Exome|Mutations|*Multiple Abnormalities|Dyneins|Testis|*INDEL Mutation|Exons|DNAH1 protein, human 17 CFAP44 29449551 Nat Commun 2018 PMC5814398 10.1038/s41467-017-02792-7 22 0 0 10 Male|Humans|Mice|Animals|*Infertility, Male|Sperm Flagellum|*Flagellum|Sperm|Axoneme|Sequencing, Whole Exome|*Mutations|Homozygote|Microtubule Proteins|Cytoskeletal Proteins|Spermatogenesis|*Trypanosoma|DNAH1 protein, human|Dyneins 17 CPLANE1 29955609 Biomed Res Int 2018 PMC6000882 10.1155/2018/7202168 2 0 0 15 Pregnancy|Female|Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Genetic Testing|*Prenatal Diagnosis|*Fetus|Mutation|Membrane Proteins 19 CPLANE1 29605658 Eur J Med Genet 2018 10.1016/j.ejmg.2018.03.012 1 0 0 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|*Ciliopathy|Cerebellar Diseases|Polydactyly preaxial type 1|Polydactyly|Phenotype|Hypothalamic hamartomas|Hypothalamic Diseases|Nervous System Malformations|Whole Exome Sequencing|Mutations 19 CPLANE1 29321670 Eur. J. Hum. Genet. 2018 PMC5839020 10.1038/s41431-017-0019-9 1 1 0 15 Chick Embryo|Humans|Animals|*Hedgehog Proteins|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|*Ciliopathies|Eye Abnormalities|Abnormalities, Multiple|Cerebellum|Retina|Exome|*Signal Transduction|Cilia|Craniofacial Abnormalities|Membrane Proteins|Mutation|Acrocallosal Syndrome|KIF7 protein, human|Kinesin|C5orf42 protein, human 19 DCLK2 29572931 Ann. Neurol. 2018 10.1002/ana.25216 20 0 0 159 Humans|*Anti-N-Methyl-D-Aspartate Receptor Encephalitis|*Genetic Predisposition to Disease|Genome-Wide Association Study|Hashimoto's encephalitis|Hashimoto Disease|Receptors, N-Methyl-D-Aspartate|Autoantibodies 17 FAM172A 29311329 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC5789929 10.1073/pnas.1715378115 4 2 0 42 Animals|*CHARGE Syndrome|*Alternative Splicing|DNA Helicases|Mutations|Phenotype|Coloboma|DNA-Binding Proteins|Neural Crest|RNA, Messenger|Disease Models, Animal 17 FANK1 29661797 Biol Open 2018 PMC5936064 10.1242/bio.033944 3 14 0 22 Mice|Animals|*Cell Differentiation|Cilia|Respiratory Mucosa|Stem Cells|Epithelial Cells|Cells, Cultured|Forkhead Transcription Factors|Trachea|Signal Transduction|JAZF1 protein, mouse|Carrier Proteins|Nuclear Proteins 17 IPO11 29602637 Urol. Oncol. 2018 10.1016/j.urolonc.2018.03.001 4 6 0 123 *Urinary Bladder Neoplasms|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|*Disease Progression|Cell Proliferation|Cell Movement|*Thrombospondin 1|Gene Expression Regulation, Neoplastic|Prognosis|Apoptosis|Biomarkers, Tumor|Cell Line, Tumor|Oncogene|RNA, Small Interfering|Karyopherins 17 MIR486 30584337 Onco Targets Ther 2018 PMC6287550 10.2147/OTT.S180354 4 8 0 0 Humans|*RNA, Micro|*Colorectal Cancer|*Apoptosis|HCT116 Cells|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Proliferation|Cell Movement|HT29 Cells|Cell Line, Tumor|*Colonic Neoplasms|BIK protein, human|Membrane Proteins|Apoptosis Regulatory Proteins|MIRN486 microRNA, human 17 MIR486 30569158 Oncol. Rep. 2018 10.3892/or.2018.6930 2 1 0 0 *Sirtuin 1|Neoplasm Recurrence, Local|*Liver Cancer|Carcinoma, Hepatocellular|MicroRNAs|Cancer Stem Cells|Gene Expression Regulation, Neoplastic|Downregulation|Cell Proliferation|3' Untranslated Region|Cell Line, Tumor|mRNA|*Genes, Tumor Suppressor|Tumorigenesis|Apoptosis|Disease Progression 17 MIR486 30527802 Eur. J. Cell Biol. 2018 10.1016/j.ejcb.2018.11.005 0 0 0 0 *Adipose Tissue|Stem Cells|Neovascularization, Physiologic|Cell Differentiation|*Neovascularization, Pathologic|Angiogenesis Inducing Agents|Endothelial Cells|MicroRNAs|Cells, Stromal 17 MIR486 30397255 Sci Rep 2018 PMC6218514 10.1038/s41598-018-34557-7 6 2 0 0 Humans|Mice|Animals|*Exosomes|Hematopoietic Stem Cell Mobilization|Tissue Distribution|Heterocyclic Compounds|CXCL12 protein, human|Stromal Cell Derived Factor 1|CXCR4 protein, human|CXC Chemokine Receptor 4|*Kidney|*Ischemia|RNA, Micro|Human Umbilical Vein Endothelial Cells|Signal Transduction 17 MIR486 29567332 Pathol. Res. Pract. 2018 10.1016/j.prp.2018.03.013 9 2 0 0 *Carcinoma, Non-Small-Cell Lung|*Lung Cancer|Neoplasm Recurrence, Local|PTEN protein, human|*PTEN Phosphohydrolase|*Oncogene|MicroRNAs|Cell Proliferation|Cell Movement|Down-Regulation|Proto-Oncogene Proteins c-akt|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|Apoptosis 17 MIR486 29393486 Mol Med Rep 2018 PMC5865988 10.3892/mmr.2018.8550 1 6 0 0 Humans|*Esophageal Squamous Cell Carcinoma|*Computational Biology|*Esophageal Neoplasms|Carcinoma, Squamous Cell|RNA, Micro|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Gene Regulatory Networks|Kaplan-Meier Estimate|Gene Expression 17 MIR503 29774077 Theranostics 2018 PMC5957011 10.7150/thno.23012 23 43 0 0 *Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Prognosis|*Liver Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Movement|Cell Line, Tumor|Cell Proliferation|Up-Regulation|Carcinogenesis|Kaplan-Meier Estimate|*Heterogeneous-Nuclear Ribonucleoprotein Group A-B 17 MIR503 29568867 Int. J. Oncol. 2018 PMC5873897 10.3892/ijo.2018.4320 5 33 0 0 *Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|MTOR protein, human|*mTOR Protein|*Signal Transduction|Neoplasm Invasiveness|MicroRNAs|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Proliferation|*Neoplastic Processes|Cell Line, Tumor|Lymphatic Metastasis|*Autophagy 17 MYLK3 30289599 Am. J. Med. Genet. A 2018 10.1002/ajmg.a.40527 1 0 0 162 *DNA Copy Number Variations|*Heart Defects, Congenital|Genotype|Genetic Association Studies|Phenotype|Polymorphism, Single Nucleotide|*Syndrome 17 MYLK3 29518473 Toxicol. Lett. 2018 10.1016/j.toxlet.2018.03.003 1 4 0 162 Humans|*DNA Methylation|cyanoginosin LR|microcystin|*Microcystins|*Leucine|Epigenesis, Genetic|*Arginine|MIRN331 microRNA, human|*miRNA|*Hepatocyte|Hepatocellular Carcinoma|*Cell Transformation, Neoplastic|*Network, Gene|Liver Neoplasms|MAGED1 protein, human|Neoplasm Proteins|Carcinogenesis|Liver 17 MYLK3 29512785 Mol Med Rep 2018 PMC5928603 10.3892/mmr.2018.8668 1 8 0 162 Humans|*MicroRNAs|Gene Regulatory Networks|*Microarray Analysis|Protein Interaction Maps|Bioinformatics|Gene Expression Profiling|*Sepsis|Downregulation|Upregulation|Transcription Factors|Signal Transduction|GTPBP4 protein, human|Nuclear Proteins|GTP-Binding Proteins|NOP14 protein, human 17 MYO3B 30255769 BMC Genet. 2018 PMC6157101 10.1186/s12863-018-0641-8 0 0 0 42 *Epigenetic|CpG Islands|Genome-Wide Association Study|DNA Methylation|Hypertriglyceridemia|Polymorphism, Single Nucleotide|Phenotype|Triglycerides|Hypoglycemic Agents|Epigenesis, Genetic 17 NAGPA 29289611 Gene 2018 10.1016/j.gene.2017.12.054 2 0 0 19 *Stuttering|Iran|Mucolipidosis|Transferases (Other Substituted Phosphate Groups)|Homozygote|Mutations|Phenotype|Heterozygote|Phosphoric Diester Hydrolases|Introns 17 NKAIN2 29341862 Physiol. Genomics 2018 PMC5899233 10.1152/physiolgenomics.00117.2017 1 0 0 16 Humans|*Body Mass Index|Genome-Wide Association Study|Cross-Sectional Studies|Japan|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Metabolic Syndrome|Obesity|Exome|Genotype|Case-Control Studies|Cohort Studies 17 POLR2M 30190596 Nat. Struct. Mol. Biol. 2018 PMC6298426 10.1038/s41594-018-0118-5 6 28 0 96 RNA Polymerase II|Transcription Factors, TFII|Transcription, Genetic|*Gene Expression Regulation|Transcription Factor|Protein Binding|invariant chain|*Histocompatibility Antigens Class II 17 POLR2M 29339073 Gene 2018 PMC6010073 10.1016/j.gene.2018.01.029 1 24 0 96 Rats|Animals|Humans|Mice|*N-Methylaspartate|*Receptors, N-Methyl-D-Aspartate|*Signal Transduction|Protein Subunits|alpha-internexin|*Intermediate Filament Proteins|Neurons|Hippocampus|Cerebral Cortex|Brain|Protein Binding|Cells, Cultured|Co-Immunoprecipitation|Cell Line|*Ion Transport 17 RAB6C 30076712 J. Cell. Physiol. 2018 10.1002/jcp.26910 2 0 0 56 *RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Carcinogenesis|Cell Proliferation|Cell Line, Tumor|Biomarkers, Tumor|Up-Regulation 17 RAPGEF5 29401416 Dev. Cell 2018 10.1016/j.devcel.2018.01.004 0 0 0 1596 *Active Transport, Cell Nucleus|beta Catenin|Wnt Proteins|*Catenins|Cell Nucleus|Signal Transduction|Guanine Nucleotide Exchange Factor|Monomeric GTP-Binding Proteins 17 RAPGEF5 29290587 Dev. Cell 2018 PMC5818985 10.1016/j.devcel.2017.12.001 12 14 0 1596 Humans|Animals|Wnt Signaling Pathway|beta Catenin|Transport, Nuclear|KPNB1 protein, human|beta Karyopherins|*Catenins|Xenopus Proteins|*Protein Transport|Cell Nucleus|Xenopus laevis|Body Patterning|Embryonic Development 17 rnf113a 30580289 BMJ Case Rep 2018 10.1136/bcr-2017-223744 0 0 0 51 Humans|*Trichothiodystrophy Syndromes|*Siblings|ERCC2 protein, human|Xeroderma Pigmentosum Group D Protein|XPBC-ERCC-3 protein|Transcription Factor IIH|DNA Helicases|Hair Diseases|Transcription Factors|DNA Repair|Photosensitivity Disorders|Mutation|Brazil|RNF113A protein, human|DNA-Binding Proteins|MPLKIP protein, human|Adaptor Proteins, Signal Transducing 17 rnf113a 30506991 J. Cell. Biochem. 2018 10.1002/jcb.28163 1 1 0 51 Humans|*RNA Precursors|*Messenger RNA|HeLa Cells|*RNA, Messenger, Splicing|Spliceosome|Ribonucleoprotein, U4-U6 Small Nuclear|U6 small nuclear RNA|Small Nuclear RNA|Ribonucleoprotein, U5 Small Nuclear|Ribonucleoprotein, U2 Small Nuclear|Saccharomyces cerevisiae Proteins|RNA Splicing Factors|Saccharomyces cerevisiae|RNF113A protein, human|DNA-Binding Proteins|Introns|Co-Immunoprecipitations|BRR2 protein, S cerevisiae 17 rnf113a 29393393 Int. J. Oncol. 2018 10.3892/ijo.2018.4253 3 3 0 51 Humans|Mice|Animals|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Lymphatic Metastasis|Gene Expression Regulation, Neoplastic|Cell Movement|Prognosis|Cell Proliferation|Kaplan-Meier Analysis|Cell Line, Tumor|RNA Interference|Biomarkers, Tumor|Signal Transduction|Gene Knockdown Techniques|Up-Regulation|Apoptosis|*Neoplastic Processes|Immunohistochemistry 17 rnf113a 29360106 Cell Res. 2018 PMC5835773 10.1038/cr.2018.14 31 10 0 51 Humans|*Spliceosomes|Ribonucleoprotein, U4-U6 Small Nuclear|Ribonucleoprotein, U5 Small Nuclear|RNA Splicing|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|RNA, Small Nuclear|RNA Splicing Factors|RNA Precursors|Ribonucleoprotein, U2 Small Nuclear|RNA Splice Sites|Cryoelectron Microscopy|RNA Helicases|Exons|Catalytic Domain|Models, Molecular 17 STXBP6 30286088 PLoS ONE 2018 PMC6171826 10.1371/journal.pone.0203155 0 14 0 29 *DNA Methylation|*Gene Expression Profiling|CpG Islands|*Lung Cancer|Oligonucleotide Array Sequence Analysis|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|China 18 SYNM 30276801 Ann. Hum. Genet. 2018 10.1111/ahg.12287 2 0 0 1214 Humans|*Whole Exome Sequencing|*Cardiomyopathy, Dilated|desmuslin|*Heterozygote|*Intermediate Filament Proteins|*Chinese|Pedigree|Mutations|Genetic Testing|Missense Mutation 17 SYNM 29963074 Front Genet 2018 PMC6013977 10.3389/fgene.2018.00209 1 4 0 1214 Humans|Female|Adult|*Syndrome|Ulnar-mammary syndrome|Abnormalities, Multiple|Holt-Oram syndrome|Upper Extremity Deformities, Congenital|Lower Extremity Deformities, Congenital|*Ulna|Breast Diseases|Heart Septal Defects, Atrial|Phenotypes|T-Box Domain Proteins|Limb Deformities, Congenital|*Tachycardia, Ventricular|Array-Based Comparative Genomic Hybridization|Heart Defects, Congenital|Mental Retardation|*Arrhythmias, Cardiac|Russia 17 TEFM 30514634 Biophys. J. 2018 PMC6302244 10.1016/j.bpj.2018.11.004 2 2 0 45 RNA Polymerase|DNA, Mitochondrial|Mitochondrial Proteins|Mitochondria|Transcription, Genetic|Mitochondrial RNA|Transcription Factors|DNA Replication|RNA|3'-(1-butylphosphoryl)adenosine|Amino Acid Sequence|*Complement Factor B 17 TEFM 30190598 Nat. Struct. Mol. Biol. 2018 PMC6583890 10.1038/s41594-018-0122-9 6 2 0 45 Humans|*Transcription, Genetic|Transcription Factors|DNA-Directed RNA Polymerases|Mitochondrial Proteins|DNA, Mitochondrial|Promoter Regions, Genetic|Mitochondria|mtRNA|Genome, Mitochondrial|Amino Acid Sequence|RNA|TEFM protein, human 17 TEFM 29945721 Trends Genet. 2018 10.1016/j.tig.2018.05.009 11 0 0 45 Humans|Animals|*B-DNA|*Mitochondria|DNA, Mitochondrial|Transcription, Genetic|Transcription Factors|RNA Polymerase|Mitochondrial Proteins|DNA-Binding Proteins|Gene Expression Regulation|Mitochondrial RNA|DNA Replication|TEFM protein, human 17 TRHDE 30518145 Int J Mol Sci 2018 PMC6321144 10.3390/ijms19123879 3 0 0 27 Humans|*Cerebral Hemorrhage|*Genetic Polymorphisms|Genetic Predisposition to Disease|Genotype|Alleles|Asians|Genetic Variation|Apolipoproteins E|European Continental Ancestry Group|Risk Factors|Ethnicity|Incidence 17 TRHDE 29783944 BMC Genomics 2018 PMC5963081 10.1186/s12864-018-4777-8 3 5 0 27 Male|Sheep|Animals|*Genome-Wide Association Study|*Acids, Fatty|*Genome|*Genomics|Phenotype|Polymorphism, Single Nucleotide 17 TRIM47 29291351 Nat. Med. 2018 10.1038/nm.4461 13 4 0 68 Mice|Animals|*Non-alcoholic Fatty Liver Disease|CYLD protein, human|*Deubiquitinating Enzyme CYLD|Liver|Diet, High-Fat|Hepatocytes|Liver Cirrhosis|Fibrosis|Inflammation|MAP Kinase Kinase Kinases|Insulin Resistance|E3 Ligase|Ubiquitination|Signal Transduction|Apoptosis|Disease Progression 17 ATP5G3 28672194 Transl Oncol 2017 PMC5496479 10.1016/j.tranon.2017.06.002 4 1 0 115 Humans|*Carcinoma, Renal Cell|ATP5B protein, human|oligomycin sensitivity-conferring protein|*Mitochondrial Proton-Translocating ATPases|Kidney Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Downregulation|Biomarkers, Tumor|Immunohistochemistry|Carcinogenesis|Mitochondria|Cohort Studies|ATP5D protein, human|ATP5S protein, human|ATP5I protein, human|ATPAF1 protein, human|Molecular Chaperones 17 ATP5G3 28289229 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5380099 10.1073/pnas.1702357114 60 0 0 115 Humans|*Mitochondrial Transmembrane Permeability-Driven Necrosis|Mitochondrial Proton-Translocating ATPases|Mitochondrial Membrane Transport Proteins|Mitochondria|Protein Subunits|Protein Conformation|*Nitric Oxide Synthase|Permeability|Calcium|Adenosine Triphosphate 17 BTBD7 28946551 Cancer Biomark 2017 10.3233/CBM-170262 2 4 0 55 Humans|*Carcinoma, Adenoid Cystic|*Epithelial-Mesenchymal Transition|Salivary Gland Neoplasms|Snail Family Transcription Factors|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Cell Line, Tumor|Transcription Factors|BTBD7 protein, human 17 BTBD7 28506999 Development 2017 PMC5482991 10.1242/dev.146894 9 2 0 55 *Morphogenesis|*Epithelial Cell|Cell Adhesion|Cell Motility|Cadherins|Submandibular Gland|Organ Culture Techniques 17 C2orf40 29080679 J. Invest. Dermatol. 2017 10.1016/j.jid.2017.09.045 25 0 0 0 Humans|dimethylaniline monooxygenase (N-oxide forming)|*Dipeptidyl Peptidase 4|*Fibroblast|Oxygenases|*Skin|Cells, Cultured|Base Sequence|Membrane Proteins|SFRP2 protein, human|DPP4 protein, human|LSP1 protein, human|Microfilament Proteins 17 C2orf40 28870864 Gene 2017 10.1016/j.gene.2017.08.041 2 6 0 0 Humans|Sp1 protein, human|*Sp1 Transcription Factor|*Promoter Regions, Genetic|*DNA Methylation|CpG Islands|Transcription Initiation Site|Binding Site|5' Untranslated Region|Regulatory Sequences, Nucleic Acid|*Gene Expression|Mithramycin|Chromatin Immunoprecipitation|Protein Binding|C2orf40 protein, human 17 C2orf40 28410214 Oncotarget 2017 PMC5522041 10.18632/oncotarget.16713 0 6 0 0 Animals|Humans|Cell Proliferation|Cell Line, Tumor|Xenograft Model Antitumor Assays|peptide B|Cell Movement|Gene Expression Regulation, Neoplastic|Antineoplastic Agents|Tumor Burden|Cell Cycle|Lung Cancer|Peptides|Disease Models, Animal|Peptide Fragments|C2orf40 protein, human 17 C2orf40 28111977 Epigenomics 2017 10.2217/epi-2016-0120 4 0 0 0 *RNA, Long Noncoding|*Carcinoma, Non-Small-Cell Lung|*DNA Methylation|*Lung Neoplasms|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Regulatory Networks|RNA, Messenger|Computational Biology 17 CAMK2N2 28642476 Sci Rep 2017 PMC5481336 10.1038/s41598-017-04355-8 6 19 0 46 Animals|Mice|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|Long-Term Memory|Memory|Hippocampus|Fear|Long-Term Potentiation|Learning|Phosphorylation|*Amnesia|Synapses|Camk2n2 protein, mouse|Carrier Proteins 17 CAMSAP1 29185983 Elife 2017 PMC5706958 10.7554/eLife.29328 16 16 0 94 Animals|Humans|*Dyneins|NUMA1 protein, human|*Nuclear Matrix-Associated Proteins|*Microtubules|*Antigens, Nuclear|*Mitosis|Dynactin|Spindle Apparatus|Microtubule-Associated Proteins|Nuclear Proteins|Cell Cycle|HeLa Cells 17 CAMSAP1 28143451 BMC Cancer 2017 PMC5286827 10.1186/s12885-017-3087-x 14 1 0 94 Humans|Male|*Prostate|*Messenger RNA|*Extracellular Vesicle|*Prostate Cancer|Exosomes|Cell-Derived Microparticles|Cell Line, Tumor|Biomarkers, Tumor 17 CFAP44 29277146 Reprod Sci 2017 10.1177/1933719117749756 4 2 0 10 Humans|Male|*Sperm Flagellum|Infertility, Male|Spermatozoa|*Multiple Abnormalities|Microtubule Proteins|Homozygote|Whole Exome Sequencing|Cytoskeletal Proteins|Mutations 17 CFAP44 28887034 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.09.010 1 1 0 10 Humans|Animals|Mice|*Tubulin|*Cilia|*Secretory Pathway|Cytoskeletal Proteins|*Flagella|Bacterial Proteins|Cell Division|Escherichia coli 17 CFAP44 28552195 Am. J. Hum. Genet. 2017 PMC5473723 10.1016/j.ajhg.2017.04.012 33 2 0 10 Humans|Female|Male|Mice|Animals|Comparative Genomic Hybridization|Sperm Motility|*Sperm Flagellum|*Infertility, Male|Sperm|Sequencing, Whole Exome|Spermatozoa, Abnormal|Homozygote|Flagella|Microtubule Proteins|Testis|*Multiple Abnormalities|Cytoskeletal Proteins|Mutations|Cohort Studies|DNAH1 protein, human|Dyneins 17 CPLANE1 29146704 Clin J Am Soc Nephrol 2017 PMC5718273 10.2215/CJN.05660517 8 0 0 15 Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Prospective Studies|Ciliopathy|*Kidney Disease|Membrane Proteins|Adaptor Proteins, Signal Transducing|Mutation|Pedigree|Heterogeneities, Genetic 19 CPLANE1 28631893 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38336 1 0 0 15 Humans|Orofaciodigital syndrome 6|*Orofaciodigital Syndromes|Agenesis of Cerebellar Vermis|Meckel syndrome type 1|Ciliary Motility Disorders|Eye Abnormalities|Polycystic Kidney Diseases|Retinitis Pigmentosa|Encephalocele|Abnormalities, Multiple|*Alleles|Cerebellum|Retina|Mutation|Phenotype|Homozygote|Tctn1 protein, human|Membrane Proteins 19 CPLANE1 28431631 J. Neurol. Sci. 2017 10.1016/j.jns.2017.02.065 2 0 0 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Neuroimaging|*Mutations|*Nervous System Malformations|Membrane Proteins|Magnetic Resonance Imaging|C5orf42 protein, human 19 DCLK2 29095916 PLoS ONE 2017 PMC5667772 10.1371/journal.pone.0187268 1 2 0 159 Pregnancy|Female|Cattle|Animals|*Vitrification|*Morula|*Freezing|*Transcriptome|*Blastocysts|Cryopreservation|Embryo Culture Techniques|Embryonic Development|Implantation, Embryo 17 FAM172A 28927116 Oncol Lett 2017 PMC5588006 10.3892/ol.2017.6585 3 9 0 42 Humans|Neoplasm Recurrence, Local|CEACAM5 protein, human|Carcinoembryonic Antigen|*Colorectal Carcinoma|CA-19-9 Antigen|Prognosis|Biomarkers, Tumor|Neoplasm Staging|Disease-Free Survival|GPI-Linked Proteins|Nucleotides|FAM172A protein, human|Proteins 17 FAM172A 28618931 Tumour Biol. 2017 10.1177/1010428317699126 3 0 0 42 Humans|*Neoplastic Cells, Circulating|*Colorectal Cancer|Prognosis|Epithelial-Mesenchymal Transition|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|In Situ Hybridization|Cell Line, Tumor|FAM172A protein, human|Proteins 17 FAM172A 28496339 Onco Targets Ther 2017 PMC5422502 10.2147/OTT.S140813 0 0 0 42 *Neoplastic Cells, Circulating|*Colorectal Cancer|*Colonic Neoplasms|*Cell Count 17 FAM172A 28440497 Oncol. Rep. 2017 10.3892/or.2017.5592 4 1 0 42 Humans|*Prognosis|*Colorectal Cancer|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|MicroRNAs|Cell Proliferation|3' Untranslated Region|Biomarkers, Tumor|Cell Line, Tumor|*Colonic Neoplasms|*Neoplastic Processes|FAM172A protein, human|Proteins 17 FAM172A 28408845 Onco Targets Ther 2017 PMC5384730 10.2147/OTT.S118346 0 4 0 42 Humans|*Neoplastic Cells, Circulating|*Colorectal Cancer|Prognosis|Biomarkers, Tumor|Epithelial-Mesenchymal Transition|*Colonic Neoplasms|Cell Separation|*Cell Count|Cell Line, Tumor|FAM172A protein, human|Proteins 17 FANK1 29097723 Sci Rep 2017 PMC5668427 10.1038/s41598-017-15062-9 2 0 0 22 Humans|Child|*Genetic Linkage|*Vesico-Ureteral Reflux|Polymorphism, Single Nucleotide|Heterogeneities, Genetic|Case-Control Studies|*Chromosome Structures|Sibling|GLRX3 protein, human|Carrier Proteins 17 GNB1L 28139055 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2017 10.1002/ajmg.b.32515 4 0 0 56 Adolescent|Humans|Male|*DiGeorge Syndrome|*Neuroanatomy|MicroRNAs|RNA-Binding Proteins|*Psychosis|Shprintzen Golberg craniosynostosis|*Arachnodactyly|Schizophrenia|Catechol O-Methyltransferase|*Marfan Syndrome|*Craniosynostoses|Genotype|SNPs|Genetic Predisposition to Disease|Psychiatric Status Rating Scales|Neuropsychological Tests|Chromosome Deletion|Alleles 17 IPO11 28736931 Clin. Pharmacol. Ther. 2017 PMC5828950 10.1002/cpt.798 11 7 0 123 Humans|Mice|Animals|*Fenofibrate|*Diabetes Mellitus, Type 2|*Lipids|Dyslipidemia|Hypolipidemic Agents|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Fibrates|Cardiovascular Disease|Risk Factors|Drug Therapy, Combination|SMAD3 protein, human|*Smad3 Protein|IPO11 protein, human|beta Karyopherins 17 IPO11 28193700 J. Cell Biol. 2017 PMC5350510 10.1083/jcb.201604025 15 29 0 123 *Active Transport, Cell Nucleus|PTEN protein, human|*PTEN Phosphohydrolase|*Receptors, Cytoplasmic and Nuclear|Cell Nucleus|Cytoplasm|Cell Line, Tumor|*Genes, Tumor Suppressor|Karyopherins 17 IPO11 28193699 J. Cell Biol. 2017 PMC5350522 10.1083/jcb.201612014 0 13 0 123 Humans|PTEN protein, human|*PTEN Phosphohydrolase|beta Karyopherins|Cytoplasm|Cell Nucleus|HeLa Cells|Protein Transport 17 MIR486 28339053 Int. J. Oncol. 2017 PMC5403184 10.3892/ijo.2017.3928 6 23 0 0 Humans|Adolescent|Young Adult|*Osteosarcoma|Neoplasm Invasiveness|Cell Proliferation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Apoptosis|Cell Line, Tumor|Transfection|Signal Transduction|Prognosis|MIRN486 microRNA, human 17 MIR503 29164842 Panminerva Med 2017 10.23736/S0031-0808.17.03386-9 1 0 0 0 Male|*Genes, Tumor Suppressor|MicroRNAs|Cell Proliferation|3' Untranslated Regions|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Apoptosis|Colorectal Cancer|Hepatocellular Carcinoma|mRNA|Lung Cancer|Liver Neoplasms 17 MIR503 28849168 Mol Med Rep 2017 PMC5647079 10.3892/mmr.2017.7278 3 19 0 0 Humans|*Laryngeal Neoplasms|*Oncogenes|*Head and Neck Squamous Cell Carcinoma|*Oncogenesis|MicroRNAs|*Apoptosis Regulatory Proteins|Cell Proliferation|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Downregulation|Lymphatic Metastasis|Cell Line, Tumor|Cell Movement|Upregulation|Head and Neck Neoplasms|PDCD4 protein, human|RNA-Binding Proteins|MIRN503 microRNA, human 17 MIR503 28656281 Mol Med Rep 2017 PMC5562074 10.3892/mmr.2017.6816 0 17 0 0 Humans|*Insulin-Like Growth Factor I|IGF1R protein, human|*Receptors, Somatomedin|MicroRNAs|Cell Proliferation|*Receptor, IGF Type 1|Downregulation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Movement|Cell Line, Tumor|Proto-Oncogene Proteins c-akt|Signal Transduction|Apoptosis|MCF7 Cell|Upregulation|*Neoplastic Processes|MIRN503 microRNA, human 17 MYLK3 29235529 Sci Rep 2017 PMC5727479 10.1038/s41598-017-17769-1 6 14 0 162 Humans|Mice|Animals|Familial dilated cardiomyopathy|*Cardiomyopathy, Dilated|myosin light chain 2|Cardiac Myosins|*Mutations|Pedigree|Exome|Myosin Light Chains|Phenotypes|Troponin T|Myosin Light Chain Kinase 17 MYLK3 28350786 Br. J. Cancer 2017 PMC5482730 10.1038/bjc.2017.83 4 15 0 162 Humans|Female|*Methylation|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Fallopian Tube Neoplasms|Cytoreduction Surgical Procedures|Peritoneal Neoplasms|Neoplasm, Residual|Disease-Free Survival|Neoplasm Staging|Promoter Regions, Genetic|*Biomarkers 17 NKAIN2 28381166 Tumour Biol. 2017 10.1177/1010428317698364 3 0 0 16 Humans|*Down-Regulation|*Pancreatic Cancer|Gene Expression Regulation, Neoplastic|MicroRNAs|Genes, Tumor Suppressor|RNA, Small Interfering|Cell Proliferation|Cell Movement|Cell Line, Tumor|Apoptosis|Quantitative Real Time Polymerase Chain Reaction|Upregulation|Lentivirus|Fluorouracil|Transcription Factors|Transcriptional Activation 17 RAB6C 28351298 Tumour Biol. 2017 10.1177/1010428317694573 12 0 0 56 Humans|Female|*Uterine Cervical Neoplasms|*DNA Methylation|*B-DNA|Cervical Intraepithelial Neoplasia|Squamous Cell Carcinoma|Promoter Regions, Genetic|Death-Associated Protein Kinases|Cervix Uteri|Cancer Biomarkers|Tumor Suppressor Proteins|Sensitivity and Specificity|Receiver Operating Characteristic|ARHGAP6 protein, human|GTPase-Activating Proteins|IKBKG protein, human|I-kappa B Kinase|PCDH10 protein, human|Cadherins 17 RAB6C 28255813 Virchows Arch. 2017 10.1007/s00428-017-2094-2 9 0 0 56 Humans|*CpG Islands|*Squamous Cell Carcinoma of Head and Neck|*DNA Methylation|*Tongue Neoplasms|Head and Neck Neoplasms|Promoter Regions, Genetic|Carcinoma, Squamous Cell|Prognosis|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Kaplan-Meier Analysis|LRPPRC protein, human|Neoplasm Proteins 17 rnf113a 29144457 Nature 2017 PMC6458054 10.1038/nature24484 9 29 0 51 Humans|*DNA Repair|Alkylation|DNA Damage|UBB protein, human|*Ubiquitin|AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase|DNA-Binding Proteins|*Signal Transduction|DNA|Alkylating Agents|Mutagenesis|*Biochemical Phenomena|Antineoplastic Agents, Alkylating|Dealkylation|RNF113A protein, human 17 rnf113a 28978524 Am. J. Physiol., Cell Physiol. 2017 PMC5792167 10.1152/ajpcell.00193.2017 2 2 0 51 Humans|HIV Infections|CXCR4 protein, human|*Receptors, CXCR4|CXCL12 protein, human|Chemokine CXCL12|*Signal Transduction|Ubiquitination|Ubiquitin-Protein Ligases|Repressor Proteins|HeLa Cells 17 STXBP6 29020941 BMC Genet. 2017 PMC5637327 10.1186/s12863-017-0549-8 1 6 0 29 Swine|Male|Animals|Humans|*Skatole|*Chromosomes, Human, Pair 7|Quantitative Trait Loci|Breeding|Genome-Wide Association Study|Chromosome Mapping|Haplotypes|Meat|Polymorphism, Single Nucleotide|Androstenes|Orchiectomy 18 STXBP6 28198450 Sci Rep 2017 PMC5309775 10.1038/srep42573 4 2 0 29 Humans|Female|*Lung Adenocarcinoma|Lung Cancer|DNA Methylation|Adenocarcinoma|Promoter Regions, Genetic|CpG Islands|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Epigenetic|Prognosis|Biomarkers, Tumor|Cell Proliferation|Cell Line, Tumor|Gene Expression Profiling|Downregulation|STXBP6 protein, human|Carrier Proteins 18 SYNM 29253577 J. Neurosci. Methods 2017 10.1016/j.jneumeth.2017.12.004 2 0 0 1214 Humans|Mice|Animals|*Fourier Analysis|*Locomotion|Gait|Gait Disorders, Neurologic|Substantia Nigra|Disease Models, Animal 17 SYNM 29247678 J. Mol. Cell. Cardiol. 2017 PMC5850968 10.1016/j.yjmcc.2017.12.005 8 2 0 1214 Mice|Animals|desmuslin|*Intermediate Filament Proteins|Desmin|Muscle, Skeletal|Sarcomeres|Sarcolemma|Costameres|Cytoskeleton|Myocardium|Cardiomyocytes 17 TEFM 29149603 Cell 2017 PMC6590061 10.1016/j.cell.2017.10.036 27 9 0 45 Humans|*Mitochondria|*Transcription, Genetic|Transcription Factors|RNA Polymerase|Mitochondrial Proteins|Transcription Initiation, Genetic|DNA-Binding Proteins|Promoter Regions, Genetic|DNA, Mitochondrial|Methyltransferases|DNA Replication|*Biochemical Phenomena 17 TEFM 29033127 Cell 2017 PMC5798601 10.1016/j.cell.2017.09.035 16 5 0 45 Humans|*Transcription, Genetic|*Mitochondria|mtDNA|Transcription Factor|Mitochondrial Proteins|DNA-Directed RNA Polymerases|Genome, Mitochondrial|Transcription Termination, Genetic|RNA|Gene Expression Regulation|G-Quadruplexes|DNA Replication|TEFM protein, human 17 TEFM 28951827 Mol Metab 2017 PMC5605719 10.1016/j.molmet.2017.05.014 10 22 0 45 Diabetes Mellitus, Type 2|Genome-Wide Association Study|*Mitochondria|Transcription Factors|Insulin|DNA-Binding Proteins|Insulin-Secreting Cells|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Oxidative Stress|*B-Lymphocytes 17 TEFM 28882896 J. Biol. Chem. 2017 PMC5672038 10.1074/jbc.M117.797480 8 0 0 45 Humans|*Saccharomyces cerevisiae|*Bacteriophage T7|bacteriophage T7 RNA polymerase|*RNA Polymerases|*Mitochondria|Saccharomyces cerevisiae Proteins|*Viral Proteins|Mitochondrial Proteins|Transcription, Genetic|*Yeast, Dried|Transcription Factors|RNA Polymerase B|Promoter Regions, Genetic|Amino Acid Sequence|POLRMT protein, human|RPO41 protein, S cerevisiae 17 TRHDE 29168350 Mol Genet Genomic Med 2017 PMC5823676 10.1002/mgg3.346 4 22 0 27 *Haplotypes|*Translocation, Genetic|*Phenotypes|Chromosome Breakpoints|Chromosome Mapping|Pedigree|Heterozygote|In Situ Hybridization, Fluorescence|Finland 17 TRHDE 29046615 Cancer Cell Int. 2017 PMC5640938 10.1186/s12935-017-0458-y 6 4 0 27 *Oncogenes|*Genomics|Computational Biology|*Glioma|Mutation|Software|Mutation Frequencies|Biomarkers, Tumor 17 TRHDE 28386672 Endocr. Pathol. 2017 10.1007/s12022-017-9479-2 5 0 0 27 Male|*Pheochromocytoma|*Paraganglioma|*Adrenal Gland Neoplasms|Mutation|Disease-Free Survival|Genes, cdc|Messenger RNA 17 TRIM47 28629823 Gene 2017 10.1016/j.gene.2017.06.017 1 1 0 68 Animals|Mice|*Carps|Fish Proteins|Fish Diseases|Poly I-C|Immunity, Innate|mRNA|TRIM Protein Family|DNA, Complementary|Amino Acid Sequence|DNA Viruses|Phylogeny|Antiviral Agents|Virus 17 TRIM47 28186994 Oncotarget 2017 PMC5410258 10.18632/oncotarget.15188 5 20 0 68 Humans|Mice|Animals|*Prognosis|Mice, Nude|*Lung Carcinoma, Non-Small-Cell|Lung Neoplasms|Adenocarcinoma|Cell Proliferation|Cell Migration|Carcinoma, Squamous Cell|Biomarkers, Tumor|Neoplasm Staging|Neoplasm Invasiveness|*Carcinogenesis|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Lymphatic Metastasis|Tumor Cells, Cultured|Apoptosis|Cell Cycle 17 ATP5G3 27698747 Exp Ther Med 2016 PMC5038183 10.3892/etm.2016.3648 4 9 1 115 Humans|*RNA, Long Noncoding|*Stomach Neoplasms|*Celecoxib|Gene Regulatory Networks|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Sequencing, RNA|Protein Interaction Maps 17 ATP5G3 26869356 Biomedicine (Taipei) 2016 PMC4751096 10.7603/s40681-016-0003-7 14 20 1 115 Mice|Animals|*Peroxisome Proliferator-Activated Receptor alpha|*Transcriptome|Phenofibrate|Transcription Factors|*Mitochondria|Hypolipidemic Agents|*Cell Transformation, Neoplastic|Gene Expression Regulation|*Tumorigenesis|Downregulation|*Energy Metabolism|Transcriptional Activation|Up-Regulation|Ndufa1 protein, mouse|Membrane Proteins|NDUFA5 protein, mouse|NADH Dehydrogenase 17 BTBD7 27983936 Oncol. Res. 2016 10.3727/096504016X14772349843854 3 2 0 55 *Epithelial-Mesenchymal Transition|Carcinoma, Non-Small-Cell Lung|Lung Cancer|*Drug Resistance, Neoplasm|Neoplasm Recurrence, Local|Cancer Stem Cells|AC133 Antigen|Cell Movement|Cell Line, Tumor|Cell Proliferation|Liver Cancer|Antigens, CD|Xenograft Model Antitumor Assays|Apoptosis|Cell Transformation, Neoplastic 17 BTBD7 27540976 Cancer Biomark 2016 10.3233/CBM-160629 2 0 0 55 Animals|*Carcinoma, Adenoid Cystic|*Slug|Salivary Gland Neoplasms|*Prognosis|Snail Family Transcription Factors|Epithelial-Mesenchymal Transition|Neoplasm Invasiveness|Cell Movement|Neoplasm Proteins|Transcription Factor|Cadherins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Lung Cancer 17 BTBD7 27369076 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.06.140 1 0 0 55 Pregnancy|Female|Mice|Animals|Brachyury protein|*Fetal Proteins|*T-Box Domain Proteins|Morphogenesis|FN1 protein, human|Fibronectin|Submandibular Gland|Salivary Glands|Transcription Factors|SOX2 protein, human|SOXB1 Transcription Factors|Epithelial Cells|Gene Expression Regulation, Developmental|Cell Movement|*Embryonic Development|Organ Culture Techniques|Btbd7 protein, mouse|Nuclear Proteins 17 C2orf40 27990492 JSM Alzheimers Dis Relat Dement 2016 PMC5157699 2 0 0 0 Humans|Mice|Animals|*Alzheimer Disease|Neurofibrillary Tangles|tau Proteins|Amyloid beta-Protein Precursor|Microglia|Cerebral Cortex|Mice, Transgenic|Neurons|Choroid Plexus|Cytokines|C2orf40 protein, human 17 C2orf40 27796151 Thyroid 2016 PMC5314727 10.1089/thy.2016.0285 14 0 0 0 *Thyroid Carcinoma, Anaplastic|*Upregulation|Thyroid Cancer|Gene Expression Regulation, Neoplastic|*Cell Cycle|MicroRNAs|Down-Regulation|Gene Expression Profiling|*Transcriptional Activation|Biomarkers, Tumor|*B-Lymphocytes|Computational Biology|Signal Transduction|*M Phase 17 C2orf40 27698864 Oncol Lett 2016 PMC5038444 10.3892/ol.2016.4935 1 2 0 0 Esophageal Neoplasms|*Cell Proliferation|Telomerase|Carcinoma, Squamous Cell|Telomere|TYRP1 protein, human|*Membrane Glycoproteins|*Cell Cycle|RNA, Messenger|DNA-Binding Proteins 17 C2orf40 27113428 J. Invest. Dermatol. 2016 10.1016/j.jid.2016.03.042 5 0 0 0 Humans|*Epigenomics|*DNA Methylation|CpG Islands|Sezary Syndrome|Promoter Regions, Genetic|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|Skin Neoplasms|Biomarkers, Tumor 17 CAMSAP1 27958650 J. Cell. Biochem. 2016 10.1002/jcb.25838 2 0 0 94 Humans|*mRNA|*Calmodulin|*Spectrin|*Osteoblasts|MicroRNAs|Cell Differentiation|Human Umbilical Vein Endothelial Cells|Coculture|Extracellular Matrix|Downregulation|Upregulation|Tissue Engineering|*Synapsins|MIRN126 microRNA, human 17 CAMSAP1 27231092 J. Cell. Sci. 2016 PMC4958304 10.1242/jcs.189076 20 18 1 94 Animals|Humans|Drosophila melanogaster|*Microvilli|*Microtubules|*Epithelium|Drosophila Proteins|*Protein Transport|Microtubule-Associated Proteins|Cell Polarity|Actin|Actin Cytoskeleton|Cytoskeleton|Microfilament Proteins|Embryo, Nonmammalian|Cell Membrane|Binding Proteins|Camsap3 protein, human|shot protein, Drosophila|nuf protein, Drosophila 17 FANK1 27060496 Cell. Signal. 2016 10.1016/j.cellsig.2016.03.012 7 13 0 22 Humans|*Transcription Factor AP-1|*Signal Transduction|*Apoptosis|Intracellular Signaling Peptides and Proteins|*YY1 Transcription Factor|TYRP1 protein, human|*Membrane Glycoproteins|Ubiquitination|Tumor|RYBP protein, human|Fank1 protein, human|DNA-Binding Proteins|Transcription Factors 17 IPO11 27689332 Oncotarget 2016 PMC5342767 10.18632/oncotarget.12315 2 4 0 123 Humans|*Urinary Bladder Neoplasms|*Prognosis|*DNA Copy Number Variations|*Whole Exome Sequencing|Cystectomy|Neoplasm Invasiveness|Urinary Bladder|Disease Progression|*Databases, Genetic|Lymph Node Excision|Karyopherins|IPO11 protein, human|beta Karyopherins 17 MIR486 27748875 Mol Med Rep 2016 PMC5102002 10.3892/mmr.2016.5845 1 3 1 0 Mice|Animals|*Carcinoma, Lewis Lung|*Granulocytes|Myeloid-Derived Suppressor Cells|Cell Differentiation|MicroRNAs|Myeloid Cells|*CD8-Positive T-Lymphocytes|*CD4-Positive T-Lymphocytes|Monocytes|Gene Expression Regulation, Neoplastic|Cell Proliferation|Spleen 17 MIR486 27081922 Mol Med Rep 2016 PMC4878579 10.3892/mmr.2016.5114 8 7 1 0 Humans|*Nonsmall Cell Lung Cancer|*miRNAs|*Prognosis|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate|Risk Factor|Cell Proliferation|Cohort Studies 17 MIR486 26870998 Oncotarget 2016 PMC4890978 10.18632/oncotarget.7264 29 4 1 0 *Lung Cancer|Carcinoma, Non-Small-Cell Lung|*RNA, Micro|*Data Analysis|Adenocarcinoma|Biomarkers, Tumor|Carcinoma, Squamous Cell|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|RNA, Messenger|Real-Time Polymerase Chain Reaction|*Genetic Profile 17 MIR503 27840964 Oncol. Rep. 2016 10.3892/or.2016.5220 7 2 0 0 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Eukaryotic Initiation Factor-4E|*Fluorouracil|miRNAs|Gene Expression Regulation, Neoplastic|Hep G2 Cells|Upregulation|Down-Regulation|Cell Proliferation|Drug Resistance, Neoplasm|Antineoplastic Agents|Apoptosis|Cell Line, Tumor|Signal Transduction|MIRN503 microRNA, human 17 MYLK3 27833563 Front Physiol 2016 PMC5080352 10.3389/fphys.2016.00480 4 9 1 162 17 MYLK3 27264040 Reprod. Toxicol. 2016 10.1016/j.reprotox.2016.06.001 1 0 0 162 Mice|Animals|*Mouse Embryonic Stem Cells|*Progesterone|*Transcriptome|*Cell Differentiation|*Myocardium|Cardiomyocytes|*Organogenesis|*Cytosol|*Calcium, Dietary|mRNA 17 MYLK3 27025239 Cardiovasc. Res. 2016 PMC4909160 10.1093/cvr/cvw069 16 0 1 162 Mice|Animals|*Myocytes, Cardiac|*Myosin-Light-Chain Kinase|*Heart Failure|Cardiac Hypertrophy|Myocardial Contraction|*Phosphorylation|Ventricular Remodeling|Myosin Light Chains|Ventricular Function, Left|Mice, Inbred C57BL|*Atrophy 17 MYLK3 26948423 Am. J. Pathol. 2016 PMC4861759 10.1016/j.ajpath.2015.12.016 20 57 0 162 Humans|*Tight Junctions|*Permeability|*Intestines|Myosin-Light-Chain Kinase|Caco-2 Cells|*Protein-Serine-Threonine Kinases|Tumor Necrosis Factor-alpha|Intestinal Mucosa|NF-kappa B|Cell Membrane Permeability|siRNA|Signal Transduction|*Complement Factor B|3'-(1-butylphosphoryl)adenosine|Promoter Regions, Genetic|MAP Kinase Signaling System|Phosphorylation 17 MYO3B 27582493 J. Biol. Chem. 2016 PMC5077211 10.1074/jbc.M116.733741 1 0 0 42 Humans|Animals|Chlorocebus aethiops|*Actins|Myosin Type III|*Myosins|Filopodia|Stereocilia|Myosin Heavy Chains|COS Cells|Protein Binding|Myosin B 17 MYO3B 26926603 Nat Commun 2016 PMC4773517 10.1038/ncomms10833 20 22 1 42 Animals|Chlorocebus aethiops|*Myosin Type III|*Stereocilia|Mechanotransduction, Cellular|Actin|Myosin Heavy Chains|Pseudopodia|Actin Cytoskeleton|Microfilament Proteins|Hair Cells, Auditory|COS Cells|Ear, Inner 17 MYO3B 26785147 Elife 2016 PMC4758956 10.7554/eLife.12856 5 48 1 42 Chlorocebus aethiops|Animals|*Myosin Type III|*Myosin B|*Actins|Myosins|Microfilament Proteins|Stereocilia|Myosin Heavy Chains|Pseudopodia|COS Cells 17 MYO3B 26754646 J. Cell Biol. 2016 PMC4738386 10.1083/jcb.201509017 14 13 2 42 Chlorocebus aethiops|Mice|Animals|*Stereocilia|*Myosin B|*Microvilli|Myosin Type III|Myosins|Hair Cells, Auditory|Myosin Heavy Chains|Actins|Cochlea|Hearing|COS Cells|*Biological Phenomena|MYO3A protein, mouse|MYO3B protein, mouse 17 NAGPA 27127921 Mol. Reprod. Dev. 2016 10.1002/mrd.22651 5 0 0 19 Female|Cattle|Animals|*Oocytes|*Ovarian Follicle|Oogenesis|*Transcriptome Analysis|Fertilization in Vitro|Meiosis|Embryonic Development|Blastocyst|Oligonucleotide Array Sequence Analysis|Embryo, Mammalian|mRNA|Gene Expression Regulation, Developmental|Chromatin Assembly and Disassembly|Transcriptomes|Cell Nucleus 17 NKAIN2 27588475 Oncotarget 2016 PMC5325404 10.18632/oncotarget.11690 2 12 0 16 Humans|Male|In Situ Hybridization, Fluorescence|*Genes, Tumor Suppressor|*Prostate Cancers|Cell Proliferation|Cell Migration|*Transcription Factors|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Down-Regulation|DNA Methylation|*Genes, Regulator|Cell Cycle|Apoptosis|NKAIN2 protein, human|Membrane Proteins 17 NKAIN2 26770299 Int J Clin Exp Med 2016 PMC4694199 4 0 0 16 Humans|Male|*Transcription Factors|Genes, Tumor Suppressor|*Genes, Regulator|Chromosome 6, monosomy 6q|Chromosome Deletion|Exons|Chromosome Mapping|Cell Line, Tumor|Chromosomal Translocations|Prostate Cancer|Membrane Proteins|In Situ Hybridization, Fluorescence|Chromosomes, Human, Pair 6|NKAIN2 protein, human 17 POLR2M 27716820 PLoS ONE 2016 PMC5055313 10.1371/journal.pone.0163649 1 12 1 96 Animals|*RNA Polymerase II|transcription factor TFIIF|Transcription Factors, TFII|*Promoter Regions, Genetic|Transcription, Genetic|Transcription Factors|*Kinetics|Elongation Factor|RNA 17 RAB6C 27550519 J. Cell. Sci. 2016 10.1242/jcs.186817 6 3 0 56 Humans|HeLa Cells|ARHGEF10 protein, human|*Rho Guanine Nucleotide Exchange Factors|RAB8A protein, human|rab GTP-Binding Proteins|RHOA protein, human|rhoA GTP-Binding Protein|Exocytosis|Biological Transport|Secretory Vesicles|Golgi Apparatus|Cell Membrane|RNA, Small Interfering|Membrane Proteins 17 RAPGEF5 26879527 Sci Rep 2016 PMC4754774 10.1038/srep21198 4 1 1 1596 Humans|*Aptitude|*Music|*Genome, Human|Genome-Wide Association Study|Auditory Perception|Cognition|*Drama|Case-Control Studies|Finland 17 rnf113a 27994011 Mol. Cell. Biol. 2016 PMC5335513 10.1128/MCB.00580-16 7 1 0 51 Humans|*RNA Splice Sites|*RNA Splicing|Spliceosome|RNA Precursors|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|RNA, Small Nuclear|RNA Splicing Factors|DEAD-box RNA Helicases|*Catalysis|Protein Binding|Zinc Fingers|Biocatalysis|RNF113A protein, human|DNA-Binding Proteins|PRP19 protein, S cerevisiae 17 STXBP6 26993066 Diabetes 2016 PMC4996324 10.2337/db15-1489 13 6 0 29 Mice|Humans|Animals|*Insulin Secretion|Diabetes Mellitus, Type 2|Insulin|Insulin-Secreting Cells|Exocytosis|Islets of Langerhans|Glucose|Cell Line|Calcium|SOX4 protein, human|SOXC Transcription Factors 18 SYNM 27651343 Turk Neurosurg 2016 10.5137/1019-5149.JTN.17746-16.1 10 0 0 1214 Glioblastoma|Brain Neoplasms|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Cycle|Apoptosis 17 SYNM 27470516 Arterioscler. Thromb. Vasc. Biol. 2016 10.1161/ATVBAHA.116.307893 13 1 0 1214 Mice|Animals|*Down-Regulation|*Smooth Muscle Cells|*Atherosclerosis|Muscle, Smooth, Vascular|Carotid Artery Injuries|Neointima|Becaplermin|Proto-Oncogene Proteins c-sis|Mice, Knockout|Vascular Remodeling|RNA Interference|Cell Proliferation|Apolipoproteins E|Signal Transduction|Cell Movement|Hyperplasia|Phenotype|Cells, Cultured 17 SYNM 27363656 J. Surg. Res. 2016 10.1016/j.jss.2016.02.040 2 0 0 1214 Humans|*Surgical Mesh|*Hernia, Ventral|*Herniorrhaphy|Hospital Costs|Surgical Wound Infection|Retrospective Studies|*Prostheses and Implants|Biological Products 17 SYNM 26879886 Clin. Genet. 2016 10.1111/cge.12761 9 0 0 1214 Humans|*Arabs|SNPs|Cholesterol Ester Transfer Proteins|Genetic Susceptibility|Genome-Wide Association Study|Cholesterol, HDL|Genotype|Asian|Coronary Artery Disease|*Hypolipoproteinemias|Phenotype 17 TECPR2 27406698 Clin. Genet. 2016 10.1111/cge.12730 1 0 0 99 Adult|Male|Female|Humans|Child|Adolescent|*Whole Exome Sequencing|Hereditary Spastic Paraplegia|Tree, Family|Exome|Heterozygote|Phenotype|*Motor Neuron Disease|Mutation, Missense|ATPases Associated with Diverse Cellular Activities|Metalloendopeptidases|Mutation|Paraplegia|Heredity|TECPR2 protein, human|Carrier Proteins|Nerve Tissue Proteins 18 TEFM 27436287 Nucleic Acids Res. 2016 PMC5027508 10.1093/nar/gkw648 7 8 1 45 Humans|*DNA, Mitochondrial|*Mitochondria|Transcription, Genetic|Mitochondrial RNA|RNA Polymerase|Mitochondrial Genomes|Transcription Factor|*Conserved Sequence|G-Quadruplexes|Mitochondrial Proteins|RNA|Transcription Termination, Genetic|DNA Replication|POLRMT protein, human|TEFM protein, human 17 TEFM 27112570 Nucleic Acids Res. 2016 PMC4937320 10.1093/nar/gkw302 11 12 1 45 Animals|DNA, Mitochondrial|Mitochondria|Mitochondrial Proteins|Transcription, Genetic|Transcription Factors|DNA Replication|Basic-Leucine Zipper Transcription Factors|DNA Helicases|Cell Nucleus 17 TRHDE 27659016 Neoplasia 2016 PMC5031903 10.1016/j.neo.2016.07.008 4 5 1 27 Humans|endothelial PAS domain-containing protein 1|*Paragangliomas|Basic Helix-Loop-Helix Transcription Factors|Pheochromocytoma|*Mutation|Polycythemia|Adrenal Gland Neoplasms|Somatostatinoma|Genotype|Genes, Regulator|Pancreatic Neoplasms 17 TRHDE 27472808 PLoS ONE 2016 PMC4966928 10.1371/journal.pone.0159504 7 1 1 27 17 TRIM47 27583843 Medicine (Baltimore) 2016 PMC5008527 10.1097/MD.0000000000003857 3 0 1 68 Humans|Aged|*Case-Control Studies|Genome-Wide Association Study|*Leukoaraiosis|*Chinese|Methylenetetrahydrofolate reductase deficiency|Methylenetetrahydrofolate Reductase (NADPH2)|SNPs|Genetic Predisposition to Disease|Genotypes|Haplotypes|Restriction Fragment Length Polymorphism|Gene Frequency|Odds Ratio|Risk Factors|Polymerase Chain Reaction|Homocystinuria|Muscle Spasticity|Psychotic Disorders 17 TRIM47 26873435 Clin Genitourin Cancer 2016 10.1016/j.clgc.2016.01.011 8 0 0 68 Male|Humans|*Prognosis|*Prostate Cancer|Prostatectomy|Prostate|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Nuclear Proteins|Cell Proliferation|TRIM47 protein, human|Carrier Proteins|Neoplasm Proteins 17 BTBD7 25874012 J Cancer 2015 PMC4392057 10.7150/jca.11715 2 6 0 55 Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|Epithelial-Mesenchymal Transition|Prognosis|Neoplasm Proteins|*Neoplastic Processes|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Lymphatic Metastasis|Cell Line, Tumor|Cell Movement|Adaptor Proteins, Signal Transducing|BTBD7 protein, human 17 C2orf40 26622716 Oncol Lett 2015 PMC4533669 10.3892/ol.2015.3429 3 2 0 0 Humans|*Cell Proliferation|*Cell Cycle|*Esophageal Cancer|Apoptosis|TYRP1 protein, human|*Oxidoreductases|ECRG4 protein, human|Tumor Suppressor Proteins|Cell Line, Tumor|*Membrane Glycoproteins|Genes, Tumor Suppressor|Prognosis|*Cell Division|Up-Regulation|C2orf40 protein, human 17 C2orf40 25580077 Gastrointest Cancer 2015 PMC4287990 10.2147/GICTT.S49085 9 11 0 0 Humans|*Oncogenes|Genes, Tumor Suppressor|Tumor Suppressor Proteins|*Esophageal Cancer|Downregulation|*Inflammation|Cell Migration|Cell Proliferation|RNA, Messenger|DNA Methylation|Infections 17 CAMK2N2 26542171 In Vitro Cell. Dev. Biol. Anim. 2015 10.1007/s11626-015-9967-y 0 6 0 46 Mice|Animals|*Myocytes, Cardiac|*Calmodulin|*Calcium|*Adrenergic Receptor Agonist|Isoproterenol|CaM KII|L-Type Calcium Channels|Sarcoplasmic Reticulum|Calcium Signaling|Adrenergic beta-Agonists|Ryanodine Receptor Calcium Release Channel|KN 93|Benzylamines|Sulfonamides|Arrythmia|*Protein Kinase Inhibitors|Homeostasis 17 CAMSAP1 26001296 Oncotarget 2015 PMC4599287 10.18632/oncotarget.4113 12 2 1 94 Child|Humans|Adult|*Transcriptome|Acute Lymphoblastic Leukemia|Fusion Proteins, bcr-abl|Prognosis|Translocation, Genetic|Gene Expression Profiling 17 CFAP44 25602530 Pharmacogenet. Genomics 2015 10.1097/FPC.0000000000000120 2 4 2 10 PCSK9 protein, human|*Proprotein Convertase 9|*Hydroxymethylglutaryl-CoA Reductase Inhibitors|*Cholesterol, LDL|*WD Repeat|Proprotein Convertases|Anticholesteremic Agents|Hypercholesterolemia|Serine Endopeptidases|*Polymorphism, Genetic|Cholesterol|Antibodies, Monoclonal|Allele 17 CPLANE1 26479702 Epigenetics 2015 PMC4867769 10.1080/15592294.2015.1099797 14 2 1 15 Humans|Adult|Child|Child, Preschool|*Twins, Monozygotic|DNA Methylation|CpG Islands|Processes, Epigenetic|Promoter Regions, Genetic|*Psychosis|Epigenetic|Schizophrenia|Genetic Predisposition to Disease|C5orf42 protein, human 19 CPLANE1 25920555 Eur. J. Hum. Genet. 2015 PMC4717206 10.1038/ejhg.2015.84 20 1 1 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|*Genotype|Phenotype|Mutations|Polydactyly, Postaxial|Polydactyly|Membrane Proteins|Alleles|Sequencing, Next-Generation|*Cohort Studies|Heterogeneities, Genetic|Fingers|Toes 19 CPLANE1 25846457 Am. J. Med. Genet. A 2015 PMC4545386 10.1002/ajmg.a.37092 2 1 0 15 Humans|Orofaciodigital syndrome 6|*Orofaciodigital Syndromes|*Whole Exome Sequencing|*Exome|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|*Homozygote|Ciliopathy|Cerebellum|Polydactyly|Retina|Phenotype|Nervous System Malformations|Mutations|Membrane Proteins|Hamartoma 19 DCLK2 26526391 Neuron 2015 10.1016/j.neuron.2015.10.005 19 1 1 159 *Growth Cones|Axons|doublecortin protein|Nerve Regeneration|Optic Nerve Injury|Neuropeptides|Microtubule-Associated Proteins|Axotomy|Retinal Ganglion Cells|MTOR protein, human|TOR Serine-Threonine Kinases|Optic Nerve|*Cell Survival|F-Actin 17 DCLK2 25784603 Prog. Neuropsychopharmacol. Biol. Psychiatry 2015 10.1016/j.pnpbp.2015.03.004 2 1 0 159 Rats|Animals|*Imipramine|*Yohimbine|*Hippocampus|Neurogenesis|Antidepressants|Receptors, Adrenergic, alpha-2 17 FAM172A 26676844 Oncol. Rep. 2015 PMC4750756 10.3892/or.2015.4485 4 12 1 42 STAT1 protein, human|*STAT1 Transcription Factor|*Colon Cancer|*Promoter Regions, Genetic|*Apoptosis|*Colon|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Upregulation|Signal Transduction|Chromatin Immunoprecipitation|Cell Proliferation 17 FAM172A 26637224 Tumour Biol. 2015 10.1007/s13277-015-4166-8 4 1 0 42 *Colorectal Carcinoma|Matrix Metalloproteinase 2|Matrix Metalloproteinase 9|Neoplasm Invasiveness|Cell Movement|CCND1 protein, human|Cyclin D1|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Carcinogenesis|Signal Pathway|RNA, Small Interfering|*Genes, Tumor Suppressor 17 FAM172A 26573560 Mol Med Rep 2015 10.3892/mmr.2015.4548 4 5 1 42 Humans|*Thyroid Cancer, Papillary|Adenoma, Thyroid|Carcinoma, Papillary|Carcinoma|Cell Proliferation|Thyroid Gland|MAPK, p38|MAP Kinase Signaling System|Proto-Oncogene Proteins B-raf|Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|TYRP1 protein, human|*Membrane Glycoproteins|Upregulation|4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole|Imidazoles|Pyridines 17 FANK1 26548368 J. Periodont. Res. 2015 10.1111/jre.12330 5 1 1 22 Humans|*Porphyromonas gingivalis|*Lipopolysaccharides|*DNA Methylation|*B-DNA|*Fibroblasts|*Extracellular Matrix|Gingiva|Periodontal Disease|Cells, Cultured 17 FANK1 26399483 Mol. Biol. Evol. 2015 PMC5009956 10.1093/molbev/msv204 9 0 1 22 Animals|Humans|*Hominidae|Neanderthals|Gene Flow|Fossils|Genome, Human|Biological Evolution|Evolution, Molecular|Genetic Variation|Hybridization, Genetic|Genomics|Polymorphism, Genetic 17 IPO11 26173551 Alcohol. Clin. Exp. Res. 2015 PMC5587504 10.1111/acer.12786 6 0 0 123 Humans|*Alcoholism|*Genome Wide Association Analysis|Genetic Predisposition to Disease|European Continental Ancestry Group|Polymorphism, Single Nucleotide|African Americans|Case-Control Studies|Membrane Proteins 17 IPO11 26079129 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2015 PMC4851708 10.1002/ajmg.b.32329 1 10 0 123 Humans|*Attention Deficit Disorder with Hyperactivity|Leukocytes, Mononuclear|*European Continental Ancestry Group|SNPs|Genetic Predisposition to Disease|Genome-Wide Association Study|Allele Frequency|African Americans|HTR1A protein, human|*Receptor, Serotonin, 5-HT1A|Quantitative Trait Loci|Case-Control Studies|Cohort Studies|IPO11 protein, human|beta Karyopherins 17 MIR486 26526573 Tumour Biol. 2015 10.1007/s13277-015-4289-y 3 0 0 0 Humans|*miRNAs|*Leukemia, Myeloid, Acute|*Mutation|Nuclear Proteins|Gene Expression Profiling|Upregulation|FLT3 protein, human|fms-Like Tyrosine Kinase 3|MIRN1 microRNA, human|MIRN486 microRNA, human 17 MIR503 26461038 Mol Med Rep 2015 10.3892/mmr.2015.4399 3 1 0 0 *Fibroblast Growth Factor 2|*Osteosarcoma|*Cell Proliferation|Bone Neoplasms|Neoplasm Invasiveness|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|Apoptosis|Cell Line, Tumor|Upregulation|Bone 17 MIR503 26200114 PLoS ONE 2015 PMC4511561 10.1371/journal.pone.0133288 8 8 1 0 Mice|Animals|*Transcriptome|Cardiomyocytes|Cell Cycle|Gene Expression Regulation|Networks, Gene|Cell Differentiation|Cell Division|Gene Ontology|Cell Proliferation|Organogenesis|Myocardial Infarction|Up-Regulation|Downregulation 17 MYO3B 26186006 PLoS ONE 2015 PMC4505843 10.1371/journal.pone.0133422 7 1 2 42 Humans|*Genome-Wide Association Study|*Intracranial Aneurysm|Portugal|SNPs|Genetic Predisposition to Disease|Alleles|Asian Continental Ancestry Group|Genotype|Subarachnoid Hemorrhage|Case-Control Studies|Risk Factors|PRDM9 protein, human|Histone-Lysine N-Methyltransferase 17 MYO3B 26098909 PLoS ONE 2015 PMC4476619 10.1371/journal.pone.0128909 0 5 0 42 Humans|Sheep|Dogs|Animals|*Genome-Wide Association Study|*Entropion|*Genome|Genotype|Breeding|Phenotype|Sheep, Domestic|Genetics, Population|Polymorphism, Single Nucleotide|Genomics|Genetic Markers|SLC2A9 protein, human|Glucose Transport Proteins, Facilitative|KCNB1 protein, human|Shab Potassium Channels 17 MYO3B 25822849 PLoS ONE 2015 PMC4379085 10.1371/journal.pone.0122502 8 14 4 42 Animals|Humans|Chlorocebus aethiops|Myosin III|*Myosins|Filopodia|Actin|Myosin Heavy Chains|*Invertebrate|*Vertebrate|*Adaptor Proteins, Signal Transducing|COS Cells|Amino Acid Sequence|Protein Binding|Binding Site|Photoreceptor Cells|Protein Domains 17 NAGPA 26544806 Am. J. Hum. Genet. 2015 PMC4667129 10.1016/j.ajhg.2015.10.007 14 1 0 19 Humans|*Stuttering|Homozygote|Transferases (Other Substituted Phosphate Groups)|Mutations|*Protein Sorting|Heterozygote|mannose-6-phosphate|Mannosephosphates|Phosphoric Diester Hydrolases|Asian Continental Ancestry Group|Lysosome|North America|Pakistan|Cameroon 17 NAGPA 26130485 Eur. J. Hum. Genet. 2015 PMC4929873 10.1038/ejhg.2015.154 11 0 0 19 Humans|Mucolipidosis III Gamma|*Mucolipidoses|*Stuttering|Transferases (Other Substituted Phosphate Groups)|Mutations|Homozygote|Phosphoric Diester Hydrolases|GNPTG protein, human|GNPTAB protein, human 17 NAGPA 25643770 BMC Genet. 2015 PMC4342093 10.1186/s12863-015-0172-5 1 0 0 19 Humans|Child|Adult|*Stuttering|*Chinese|*Dyslexia|Transferases (Other Substituted Phosphate Groups)|Genetic Predisposition to Disease|Mutation|Phosphoric Diester Hydrolases|*Language|GNPTG protein, human|GNPTAB protein, human 17 NKAIN2 26316594 Schizophr Bull 2015 PMC4753595 10.1093/schbul/sbv119 9 0 0 16 Genome-Wide Association Study|*Genes, Modifier|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype 17 NKAIN2 26112879 J Nutrigenet Nutrigenomics 2015 10.1159/000431151 7 0 0 16 *Genome-Wide Association Study|Lipoproteins, LDL|Dietary Fats|Triglycerides|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Particle Size|Quebec 17 NKAIN2 25637059 Ital J Pediatr 2015 PMC4347966 10.1186/s13052-015-0113-y 2 0 0 16 Child|Humans|Craniofacial Abnormalities|Trisomy|Abnormalities, Multiple|Karyotyping|Developmental Disabilities|Translocation, Genetic|Gene Duplication|In Situ Hybridization, Fluorescence|Phenotypes|Autism 17 NKAIN2 25562418 Gene 2015 10.1016/j.gene.2014.12.064 3 0 0 16 Humans|*Neurofibromatosis 1|*Comparative Genomic Hybridization|*Oligonucleotide Array Sequence Analysis|*Neurofibroma|Nerve Sheath Neoplasms|Genes, Neurofibromatosis 1|*Skin Neoplasms|Chromosome Aberrations|Chromosome Deletion|Chromosomes, Human|DNA Copy Number Variations|Mutations|*Oligonucleotides|Genes, Regulator|ARHGAP18 protein, human|GTPase-Activating Proteins 17 POLR2M 26116512 J. Immunol. 2015 10.4049/jimmunol.1402341 6 1 1 96 Humans|Endothelial Cells|*Receptors, Antigen, B-Cell|*Central Nervous System Neoplasms|*Lymphoma, Non-Hodgkin|Lymphoma, Large B-Cell, Diffuse|*Proteins|Immunoglobulin Heavy Chains|galectin-3, human|Galectin 3|Nervous System 17 rnf113a 25612912 J. Med. Genet. 2015 10.1136/jmedgenet-2014-102418 14 0 2 51 *Trichothiodystrophy Syndromes|*Codon, Nonsense|Hair Diseases|Phenotype|DNA Repair|Mutation|*Genes, X-Linked 17 SYNM 25567810 Am. J. Physiol., Cell Physiol. 2015 PMC4360028 10.1152/ajpcell.00331.2014 13 0 1 1214 Mice|Animals|desmuslin|*Muscle, Skeletal|*Intermediate Filament Proteins|Sarcolemma|Muscle Contraction|Muscular Diseases|Desmin|Muscle Fibers, Fast-Twitch|Muscle Fibers, Skeletal|Costameres|Sarcomeres|Mice, Knockout|Muscle, Striated 17 TECPR2 26715604 Brain 2015 PMC5841365 10.1093/brain/awv371 24 3 3 99 Humans|Child|Spastic paraplegia 15, autosomal recessive|Hereditary Spastic Paraplegia|Spastic paraplegia 11, autosomal recessive|Absent corpus callosum cataract immunodeficiency|Agenesis of Corpus Callosum|*Autophagy|Lysosomes|Cataract|Mutations|Lysosome-Associated Membrane Glycoproteins|Vesicular Transport Proteins|Neurodevelopmental Disorders|Retinal Degeneration|Nervous System Malformations|Membrane Fusion|SPG11 protein, human|Proteins|TECPR2 protein, human 18 TECPR2 26555167 PLoS ONE 2015 PMC4640708 10.1371/journal.pone.0141824 6 0 1 99 Humans|Dogs|Animals|*Neuroaxonal Dystrophy|Pedigree|Genetic Linkage|Mutation|Paraparesis, Spastic|Lod Score|Mutation, Missense|Dog Diseases|Cerebellum|TECPR2 protein, human|Carrier Proteins|Nerve Tissue Proteins 18 TECPR2 26542466 Eur. J. Paediatr. Neurol. 2015 10.1016/j.ejpn.2015.10.003 4 0 0 99 Humans|*Dysautonomia, Familial|*Intellectual Disability|*Hereditary Sensory Neuropathy|*Mutations|Nerve Tissue Proteins|Mutation, Frame Shift|Carrier Proteins|*Autonomic Nervous System|Paraparesis, Spastic|Jews|TECPR2 protein, human 18 TECPR2 26431026 Mol. Cell 2015 10.1016/j.molcel.2015.09.010 36 25 2 99 Humans|Endoplasmic Reticulum|COP-Coated Vesicles|Protein Transport|Spastic Paraplegias, Hereditary|Vesicular Transport Proteins|Autophagy|Nerve Tissue Proteins|Secretion Pathway|Mutation|Neurodegenerative Diseases|TECPR2 protein, human|Carrier Proteins 18 TECPR2 30838228 Mov Disord Clin Pract 2015 PMC6353461 10.1002/mdc3.12184 1 0 1 99 *Spastic Paraplegia, Hereditary|Mutation 18 TEFM 25701571 Bioinformatics 2015 10.1093/bioinformatics/btv111 7 0 1 45 *Metabolic Network|Metabolic Flux Analysis|*Thermodynamic|Computational Biology|Computer Simulation|Algorithms|Models, Biological|Escherichia coli|*Physical Phenomena|Glucose 17 TEFM 25690892 Nucleic Acids Res. 2015 PMC4357710 10.1093/nar/gkv105 30 12 3 45 Humans|*Mitochondria|Transcription, Genetic|Mitochondrial Proteins|Transcription Factors|DNA-Directed RNA Polymerases|DNA, Mitochondrial|Genome, Mitochondrial|RNA|TEFM protein, human 17 TEFM 25635099 Science 2015 PMC4677687 10.1126/science.aaa0986 51 5 7 45 Humans|*Mitochondria|DNA, Mitochondrial|RNA Polymerase|Mitochondrial Proteins|Transcription, Genetic|Mitochondrial RNA|Genome, Mitochondrial|Transcription Factors|DNA Replication|Adenosine Triphosphate|*Cell Physiological Phenomena|TEFM protein, human 17 TRHDE 26690652 Oral Oncol. 2015 PMC4788701 10.1016/j.oraloncology.2015.11.012 9 2 1 27 Humans|*DNA Methylation|*B-DNA|Cross-Sectional Studies|*Oral Cancers|CpG Islands|Genes, p16|Precancerous Conditions|Cyclin-Dependent Kinase Inhibitor p16|Promoter Regions, Genetic|*Disease Progression|Carcinoma, Squamous Cell|*Neoplastic Processes|*Biomarkers 17 TRHDE 26555032 Heredity (Edinb) 2015 PMC4806575 10.1038/hdy.2015.94 41 0 2 27 Sheep|Animals|Cattle|*Goats|Genome-Wide Association Study|*Genome|*Genomics|Natural Selection|Genotype|Phenotype|Genetics, Population|Breeding|Sheep, Domestic|Genetic Variation|Genome Mapping|Domestication|Adaptation, Physiological|Polymorphism, Single Nucleotide|Egypt 17 TRHDE 25891934 Cell Cycle 2015 PMC4613559 10.1080/15384101.2015.1036209 10 0 3 27 Humans|Animals|*Transcription Factor|*Neurogenesis|*Sensory Neuron|*Pain Perception|Hereditary Sensory and Autonomic Neuropathies|Nerve Tissue Proteins|*Gene Expression Regulation|Carrier Proteins|Xenopus laevis|Nociception|Mutations|Prdm12 protein, human 17 TRIM47 25586835 Stroke 2015 PMC4306534 10.1161/STROKEAHA.114.007649 0 12 2 68 *White Matter|Leukoencephalopathies|Brain|Genome-Wide Association Study|Alzheimer Disease|*Leukoaraiosis|Stroke|Magnetic Resonance Imaging|Hypertension|Risk Factors 17 ATP5G3 24659680 J BUON 2014 0 0 0 115 *Granulocyte Colony-Stimulating Factor|Antigens, CD34|Interleukin-3|Erythroid Precursor Cells|Cell Differentiation|Cell Division|Cells, Cultured 17 BTBD7 25544168 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2014 10.11817/j.issn.1672-7347.2014.12.001 2 3 0 55 Humans|fasudil|*Carcinoma, Hepatocellular|*rho-Associated Kinases|*Liver Neoplasms|*1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine|*Protein Kinase Inhibitors|*Signal Transduction|Cell Movement|Cell Line, Tumor|Cell Proliferation|Matrix Metalloproteinase 2|*Neoplastic Processes|Apoptosis|Lung Neoplasms|BTBD7 protein, human|Neoplasm Proteins|ROCK2 protein, human 17 BTBD7 25366760 Genet. Mol. Res. 2014 10.4238/2014.October.27.10 11 0 2 55 Humans|*Stomach Neoplasms|MIRN-524 microRNA, human|MicroRNAs|MIRN204 microRNA, human|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Downregulation|Up-Regulation|Computational Biology|Signal Transduction|Metaplasia|Transcription Factors|Precancerous Conditions|SOX4 protein, human|SOXC Transcription Factors|BTBD7 protein, human|Neoplasm Proteins 17 BTBD7 25253020 BMC Cancer 2014 PMC4189533 10.1186/1471-2407-14-704 15 10 0 55 *Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|CDH1 protein, human|*Cadherins|Antigens, CD|Prognosis|Lymphatic Metastasis|Immunohistochemistry|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Adhesion|Adaptor Proteins, Signal Transducing|Lungs 17 BTBD7 24403051 Hum. Mol. Genet. 2014 PMC3990162 10.1093/hmg/ddt657 13 2 1 55 Humans|Comparative Genomic Hybridization|*Oral Cancer|Leukoplakia, Oral|*Cell Transformation, Neoplastic|Squamous Cell Carcinomas|Precancerous Conditions|*Tumorigenesis|DNA Copy Number Variations|*Genomics|Disease Progression|Chromosomes, Human|*Databases, Genetic|BTBD7 protein, human|Neoplasm Proteins|KHDRBS1 protein, human|DNA-Binding Proteins|RNA-Binding Proteins|Adaptor Proteins, Signal Transducing 17 C2orf40 25513848 Exp. Lung Res. 2014 PMC4524537 10.3109/01902148.2014.983282 3 7 0 0 Humans|*Inflammation|*Lung|Genes, Tumor Suppressor|Tumor Suppressor Proteins|*Esophageal Cancer|Cells, Epithelial|Cells, Cultured|Downregulation|Cytokines 17 C2orf40 25511108 Inflamm. Res. 2014 PMC4301958 10.1007/s00011-014-0789-2 8 5 0 0 Humans|Lymphocyte Antigen 96|*Esophageal Cancer|*Immunity, Innate|Toll-Like Receptor 4|Lipopolysaccharide Receptors|Signal Transduction|Tumor Suppressor Proteins|*Cell Membrane 17 CAMSAP1 24706919 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC4000804 10.1073/pnas.1404133111 44 2 8 94 Animals|*Microtubules|Kinesin|Microtubule-Associated Proteins|Cytoskeleton|Tubulin|Drosophila Proteins|Drosophila melanogaster|Mitosis|Cytoskeletal Proteins|Chromosome Segregation|Protein Binding|Polymerization|Drosophila|patronin protein, Drosophila 17 CAMSAP1 24603804 Int. J. Oncol. 2014 10.3892/ijo.2014.2321 12 1 4 94 Humans|*Calmodulin|*Spectrin|*Tumor Microenvironment|Laryngeal Neoplasms|miRNAs|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Prognosis|Biomarkers, Tumor|mRNA|Squamous Cell Carcinoma of Head and Neck|Real-Time Polymerase Chain Reaction|Western Blotting|Head and Neck Neoplasms|MIRN126 microRNA, human 17 CFAP44 25089948 Pharmacogenet. Genomics 2014 PMC4159722 10.1097/FPC.0000000000000081 2 4 2 10 PCSK9 protein, human|*Proprotein Convertase 9|*Simvastatin|Proprotein Convertases|Statins|Cholesterol, LDL|LDLR protein, human|Low Density Lipoprotein Receptor|Anticholesteremic Agents|Serine Endopeptidases|Cholesterol|*Plasma 17 CPLANE1 25407461 Hum. Genet. 2014 PMC4282684 10.1007/s00439-014-1508-3 9 0 4 15 Humans|Orofaciodigital syndrome 6|*Orofaciodigital Syndromes|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|Cerebellar Diseases|Cerebellum|Phenotype|Retina|Mutations|Polydactyly|Hypothalamic hamartomas|Hypothalamic Diseases|Hamartoma|Membrane Proteins|C5orf42 protein, human 19 CPLANE1 25173907 J AAPOS 2014 10.1016/j.jaapos.2014.03.006 2 0 0 15 Humans|Child|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|Apraxia, oculomotor, Cogan type|*Abnormalities, Multiple|*Cerebellum|*Retina|*Cogan Syndrome|*Apraxias|Cerebellar Diseases|Ocular Motility Disorders|Magnetic Resonance Imaging|*Phenotype|*Face 19 DCLK2 24582561 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.02.075 2 0 0 159 Animals|*Phosphorylation|doublecortin protein|*Protein Kinase|*Transcription Factor|Microtubule-Associated Proteins|Neuropeptides|Zebrafish|Protein-Serine-Threonine Kinases|Protein Binding|Microtubule|*Protein Transport|Histones|Repressor Proteins|Cell Nucleus|Cytoplasm|*Gene Expression Regulation 17 FANK1 25515583 Invest. Ophthalmol. Vis. Sci. 2014 10.1167/iovs.14-14934 6 6 1 22 *Tenascin|FN1 protein, human|*Fibronectins|*Epithelial-Mesenchymal Transition|*Capsule Opacification|neuronectin|*Extracellular Matrix Proteins|Posterior Capsule of the Lens|Lens, Crystalline|*Extracellular Matrix|*Nerve Tissue Proteins|Epithelial Cells|Cell Movement|Epithelium|Cells, Cultured|Cell Proliferation|Signal Transduction 17 FANK1 25144706 PLoS Genet. 2014 PMC4140648 10.1371/journal.pgen.1004561 56 1 9 22 Humans|Male|Selection, Genetic|Genetics, Population|Allele|Genome, Human|Haplotypes|Evolution, Molecular 17 GNB1L 24831436 Neurosci Bull 2014 PMC5562634 10.1007/s12264-014-1461-0 1 0 0 56 Humans|*Bipolar Disorder|Case-Control Studies|*Schizophrenia|SNPs|Linkage Disequilibrium|Genetic Predisposition to Disease|Depressive Disorder, Major|*Temporal Cortex|Genotype|Haplotypes|Asian Continental Ancestry Group|Allele|22q11.2 Deletion Syndrome|Intracellular Signaling Peptides and Proteins|*Regulatory Sequences, Nucleic Acid 17 IPO11 25378586 Mol. Biol. Cell 2014 PMC4294679 10.1091/mbc.E14-06-1057 13 4 2 123 KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Antioxidants|*Ubiquitin-Conjugating Enzymes|*Gene Expression Regulation|*GA-Binding Protein Transcription Factor|Cell Nucleus|Redox|Ubiquitin|Intracellular Signaling Peptides and Proteins|Nuclear Import|Cytoplasm|Oxidative Stress|Homeostasis|Mitochondria|Karyopherins 17 MIR486 24980554 Cancer Res. 2014 PMC4134725 10.1158/0008-5472.CAN-13-2817 13 20 1 0 Humans|Mice|Animals|Phosphatidylinositol 3-Kinases|ERBB2 protein, human|Receptor, ErbB-2|MicroRNAs|Transgenic Mouse|*Muscle, Skeletal|Signal Transduction|Mammary Neoplasms, Experimental|Proto-Oncogene Proteins c-akt|Cell Differentiation|Myoblasts|Tumor Necrosis Factor-alpha|Transcription Factor 17 MIR503 25269574 Mol Med Rep 2014 10.3892/mmr.2014.2591 9 7 1 0 Humans|*Carcinoma, Hepatocellular|*Adriamycin|*Hepatocellular Cancer|*HepG2 Cell|Drug Resistance, Multiple|Drug Resistance, Neoplasm|ATP Binding Cassette Transporter, Subfamily B, Member 1|Apoptosis|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B|BIRC5 protein, human|Survivin|Cell Line, Tumor|Downregulation|Proto-Oncogene Proteins c-bcl-2|Gene Expression Regulation, Neoplastic|Cell Cycle|Cell Proliferation 17 MIR503 25164015 Cancer Res. 2014 10.1158/0008-5472.CAN-14-0389 17 3 1 0 Humans|SMAD7 protein, human|Smad7 Protein|Transforming Growth Factor beta|miRNA|Gene Expression Regulation, Neoplastic|Epithelial-Mesenchymal Transition|Receptors, Transforming Growth Factor beta|Signal Transduction|Cell Line, Tumor|Oncogenesis|Multigene Family|MIRN424 microrna, human|MIRN503 microRNA, human 17 MYO3B 25500906 Oncogenesis 2014 PMC4275559 10.1038/oncsis.2014.45 6 38 0 42 Humans|*Trastuzumab|Phosphatidylinositol 3-Kinases|Early Detection of Cancer|Receptor, ErbB-2|Lapatinib|*Cell Proliferation|Receptor, ErbB-3|Antibodies, Monoclonal, Humanized|Antineoplastic Agents|Quinazolines|Drug Resistance, Neoplasm|Signal Transduction|Xenograft Model Antitumor Assays|Phosphatidylinositol 3-Kinase|Phosphorylation|RNA, Small Interfering 17 MYO3B 24496092 Heredity (Edinb) 2014 PMC3998787 10.1038/hdy.2013.137 35 1 11 42 Cattle|Animals|Female|*Tuberculosis, Bovine|*Genome-Wide Association Study|Mycobacterium bovis|Single Nucleotide Polymorphisms|Genotype|Genetic Predisposition to Disease|Phenotypes|Dairying|Haplotype|Chromosomes, Mammalian 17 NAGPA 24807205 Neurobiol. Dis. 2014 PMC4099264 10.1016/j.nbd.2014.04.019 0 0 1 19 Humans|*Stuttering|CNTNAP2 protein, human|Nerve Tissue Proteins|Transferases (Other Substituted Phosphate Groups)|Membrane Proteins|Mutations|Genetic Predisposition to Disease|Speech Disorders|Phosphoric Diester Hydrolases|Brazil|FOXP2 protein, human|Forkhead Transcription Factors|GNPTG protein, human|GNPTAB protein, human 17 POLR2M 25542908 Clin J Am Soc Nephrol 2014 PMC4348675 10.2215/CJN.02390314 2 0 0 96 *Glomerulonephritis, IGA|*Epitopes|Immunoglobulin A|Kidney|Glomerular Filtration Rate|Autoantibodies|Immunoglobulin G|Kidney Glomerulus|Case-Control Studies|Disease Progression|Biopsy 17 POLR2M 24634214 J. Biol. Chem. 2014 PMC4007455 10.1074/jbc.M113.537662 10 19 1 96 *RNA Polymerase II|*Phosphorylation|Transcription Factors, TFII|Transcription, Genetic|Transcription Factor|Gene Expression Regulation|Promoter Regions, Genetic|Protein Binding|Mitosis 17 POLR2M 24596085 J. Biol. Chem. 2014 PMC4036253 10.1074/jbc.M113.544395 4 3 1 96 *RNA Polymerase II|transcription factor TFIIF|Transcription Factors, TFII|Transcription, Genetic|Phosphorylation 17 POLR2M 24466310 PLoS ONE 2014 PMC3900694 10.1371/journal.pone.0087003 26 20 5 96 Humans|Animals|BRD4 protein, human|Nuclear Proteins|Transcription Factors|Azepines|Proto-Oncogene Proteins c-myc|Cell Cycle Proteins|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|Triazoles|Xenograft Model Antitumor Assays|Burkitt Lymphoma 17 RAPGEF5 25138019 Neuropsychologia 2014 10.1016/j.neuropsychologia.2014.08.011 6 0 0 1596 Adult|Humans|Male|Female|Adolescent|Young Adult|Genome-Wide Association Study|Sex Difference|*Face|Sex Factors|Perception, Face|Fingers|Polymorphism, Genetic 17 SYNM 25179606 J. Cell. Sci. 2014 10.1242/jcs.143164 10 0 0 1214 Mice|Animals|desmuslin|*Intermediate Filament Proteins|Desmin|Muscular Diseases|Sarcolemma|Muscle Proteins|Muscle, Skeletal|Muscle Fibers, Skeletal|Myoblasts|*Protein Binding|MSTN protein, human|Myostatin|Hypertrophy 17 TECPR2 24957906 Hum. Mol. Genet. 2014 PMC4204766 10.1093/hmg/ddu307 25 0 2 99 Humans|*Haplotypes|*Genome-Wide Association Study|*Birdshot Chorioretinopathy|HLA-A29 antigen|HLA-A Antigens|Genetic Predisposition to Disease|Allele|Chorioretinitis|Aminopeptidases|Polymorphism, Single Nucleotide|Minor Histocompatibility Antigens|European Continental Ancestry Group|Case-Control Studies|ERAP2 protein, human|TECPR2 protein, human|Carrier Proteins|Nerve Tissue Proteins 18 ATP5G3 24085430 Genet. Mol. Res. 2013 PMC5505871 10.4238/2013.September.18.1 2 0 0 115 Mice|Animals|*Mice, Inbred DBA|*Mice, Inbred C57BL|*Epigenesis, Genetic|*Genomics|Quantitative Trait Loci|*Obesity|Phenotype|Body Weight|Alcoholism|Transcriptome|Sequence Analysis, DNA|Polymorphism, Single Nucleotide 17 ATP5G3 23451031 PLoS ONE 2013 PMC3581534 10.1371/journal.pone.0055791 3 11 0 115 Humans|*HIV-1|Bayes Theorem|Non-Progressors, HIV-1|Virus Replication|HIV Infections|*Cells, B-1 17 BTBD7 23325674 Hepatology 2013 10.1002/hep.26268 23 4 2 55 Humans|Animals|*Carcinoma, Hepatocellular|*Epithelial-Mesenchymal Transition|*Liver Neoplasms|*Prognosis|Matrix Metalloproteinase 2|*BTB-POZ Domain|Neoplasm Invasiveness|Cell Motility|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Down-Regulation|Signal Transduction|Neovascularization, Pathologic|Biomarkers|BTBD7 protein, human|Neoplasm Proteins 17 C2orf40 23770814 Epigenetics 2013 PMC3857337 10.4161/epi.24626 18 4 2 0 Humans|*Genes, cdc|DNA Methylation|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|Cell Line, Tumor|Neoplasm Proteins|Cell Proliferation|Downregulation|Cell Movement|*M Phase|*Neoplastic Processes|UBE2C protein, human|Ubiquitin-Conjugating Enzymes|C2orf40 protein, human 17 CAMK2N2 23545117 Biochim. Biophys. Acta 2013 PMC3679306 10.1016/j.bbadis.2013.03.015 6 16 0 46 Humans|FUS protein, human|*RNA-Binding Protein FUS|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Mutation|Cytoplasm|Cell Nucleus|Exon|RNA Splicing|HEK293 Cells 17 CAMSAP1 24117850 J. Neurochem. 2013 PMC4016758 10.1111/jnc.12462 8 22 2 94 Rats|Animals|*Calmodulin|*Spectrin|*Neurite Outgrowth|PC12 Cells|Neurites|*Conserved Sequence|*Synapsins|Cytoskeletal Proteins|Microtubules|*Actin Cytoskeleton|TYRP1 protein, human|Membrane Glycoproteins|Protein Binding|enhanced green fluorescent protein|Green Fluorescent Proteins 17 CPLANE1 24178751 Hum. Genet. 2013 10.1007/s00439-013-1385-1 24 0 8 15 Child|Humans|*Syndrome|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Abnormalities, Multiple|Ciliopathies|Cerebellar Hypoplasia|Cerebellum|Nervous System Malformations|Retina|Polydactyly|Mutations|Hypothalamic hamartomas|Hypothalamic Diseases|Phenotype|Hamartoma 19 DCLK2 23973064 Methods Cell Biol. 2013 10.1016/B978-0-12-407757-7.00003-7 5 0 0 159 Humans|doublecortin protein|Cryoelectron Microscopy|*Microtubule-Associated Proteins|Neuropeptides|Microtubule|Tubulin|Neurons|Binding Site|Cell Movement|Brain|Microtubule Proteins 17 DCLK2 23726375 Brain Dev. 2013 10.1016/j.braindev.2013.04.013 14 0 1 159 Child|Humans|*Attention Deficit Disorder with Hyperactivity|*Autistic Disorder|*Epilepsy|Child Development Disorders, Pervasive|Comorbidity|Sclerosis, Tuberous|CNTNAP2 protein, human|Membrane Proteins|Nerve Tissue Proteins 17 DCLK2 23385585 Nat Commun 2013 PMC4017031 10.1038/ncomms2443 28 18 3 159 doublecortin protein|Synapses|Neuropeptides|Microtubule-Associated Proteins|Dendrites|Neurons|Excitatory Postsynaptic Potentials|Dendritic Spines|Disks Large Homolog 4 Protein|Receptors, AMPA|Hippocampus|Patch-Clamp Techniques|Receptors, N-Methyl-D-Aspartate|Nerve Tissue Proteins|Interneurons|Membrane Proteins|Cells, Cultured|Neuronal Plasticity 17 FAM172A 23314443 Oncol. Rep. 2013 10.3892/or.2013.2235 6 1 2 42 Humans|*Hep G2 Cells|*S Phase|Hepatocellular Carcinoma|Liver Neoplasms|NOTCH3 protein, human|*Receptor, Notch3|Cell Proliferation|Cell Cycle|Signal Transduction|Downregulation|Apoptosis|Cell Cycle Control|FAM172A protein, human|Proteins 17 FANK1 24369145 Asian J. Androl. 2013 PMC3901870 10.4103/1008-682X.122592 7 4 1 22 Humans|Male|Mice|Animals|*Testis|*Oligospermia|Spermatogenesis|Spermatocytes|In Situ Nick-End Labeling|*Apoptosis|Transcription Factor|Spermatogonia|Sperm|DNA-Binding Proteins|Meiosis|Gene Expression Regulation|Mice, Transgenic|Fank1 protein, human 17 GNB1L 23791650 Gene 2013 10.1016/j.gene.2013.06.009 3 0 0 56 Pregnancy|Female|Humans|*Comparative Genomic Hybridization|*DiGeorge Syndrome|*Prenatal Diagnosis|Conotruncal cardiac defects|Heart Defects, Congenital|Chromosome Deletion|Haploinsufficiency|Chromosomes|MED15 protein, human|Mediator Complex|UFD1L protein, human 17 MYO3B 23376709 J. Urol. 2013 10.1016/j.juro.2013.01.096 18 1 4 42 Male|Humans|*Genome-Wide Association Study|*Polymorphism, Single Nucleotide|*Prostate Cancer|Brachytherapy|Genetic Predisposition to Disease|Iodine Radioisotopes 17 NKAIN2 24205241 PLoS ONE 2013 PMC3808344 10.1371/journal.pone.0078481 5 2 0 16 Humans|Child|*Array Comparative Genomic Hybridization|*Neuroblastoma|*Transcription Factors|Mutations, Germline|Homeodomain Proteins|*Genes, Regulator|Pedigree|Anaplastic Lymphoma Kinase|Genetic Predisposition to Disease|Mutation|Receptor Protein-Tyrosine Kinases|Protein-Tyrosine Kinases|*Sodium-Potassium-Exchanging ATPase|Cell Line, Tumor|Cohort Studies|NKAIN2 protein, human|Membrane Proteins 17 NKAIN2 23903073 J. Hum. Genet. 2013 10.1038/jhg.2013.75 16 0 0 16 Humans|Young Adult|Female|Adolescent|Adult|*Genome-Wide Association Study|Republic of Korea|*Personality|Neuroticism|Personality Inventory|Extroversion|*Personality Disorders|Personality Tests|Multifactorial Inheritance|Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Anxiety Disorders|Phenotypes 17 RAB6C 23936529 PLoS ONE 2013 PMC3735572 10.1371/journal.pone.0071886 6 12 2 56 Animals|Humans|HeLa Cells|*Golgi Apparatus|*Protein Transport|Endoplasmic Reticulum|rab GTP-Binding Proteins|Transfection|*Cell Movement|*Cell Cycle|Fluorescence Microscopy 17 RAB6C 23542510 Neurobiol. Dis. 2013 10.1016/j.nbd.2013.03.010 19 8 1 56 *Charcot-Marie-Tooth Disease|*Mitochondria|Endoplasmic Reticulum|Mitochondrial Dynamics|*Homeostasis|Mitochondrial Proteins|Calcium Channels|Mitochondrial Membrane, Outer|Membrane Proteins|Nerve Tissue Proteins|Protein Transport|Mutations|Neurons|Microtubules 17 RAPGEF5 24006282 Biol. Reprod. 2013 PMC4076381 10.1095/biolreprod.113.110163 10 2 3 1596 Humans|Male|Mice|Animals|*Sperm Motility|*Epididymis|Glycogen Synthase Kinase 3|*Sperm|Acrosome|*Signal Transduction|Cyclic AMP|Phosphorylation|Dibutyryl Cyclic AMP|Guanine Nucleotide Exchange Factors|Tails, Sperm|RAPGEF3 protein, human|Rapgef4 protein, mouse 17 RAPGEF5 23434627 Genomics 2013 10.1016/j.ygeno.2013.02.003 8 0 0 1596 *Colorectal Neoplasms, Hereditary Nonpolyposis|*DNA Copy Number Variations|*DNA Mismatch Repair|Genome-Wide Association Study|Microsatellite Instability|Immunohistochemistry|DNA Repair|Tumorigenesis 17 rnf113a 24026126 Development 2013 PMC3787755 10.1242/dev.093781 15 3 0 51 Animals|Humans|*Drosophila|*Zinc Finger|Transcription Factor|Drosophila Proteins|Neural Stem Cells|Drosophila melanogaster|Cell Differentiation|Nuclear Proteins|Neurons|Nerve Tissue Proteins|Neurogenesis|Gene Expression Regulation, Developmental|Basic Helix-Loop-Helix Transcription Factors|Stem Cell Self-Renewal|Cell Proliferation|Zinc|RNF113A protein, human|DNA-Binding Proteins 17 STXBP6 23897225 Arthritis Rheum. 2013 PMC3898704 10.1002/art.38101 9 5 0 29 *Interstitial Lung Disease|*Sclerosis, Systemic|*Skin|Vital Capacity|Immunosuppressive Agents|*Gene Expression 18 STXBP6 23660444 Gen. 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Endocrinol. 2013 10.1016/j.ygcen.2013.04.028 5 0 2 29 Animals|Female|*Hydrocortisone|Atlantic Cod|Embryo, Nonmammalian|Oocyte|Embryonic Development|Transcriptome|Blastula|Gene Expression Profiling|mRNA|*Cytogenetic|Gene Expression Regulation, Developmental|Glucocorticoid Receptor|*Eggs 18 TECPR2 24284334 Autophagy 2013 PMC5396092 10.4161/auto.27173 6 0 1 99 Humans|*Paraparesis, Spastic|Spastic paraplegia 15, autosomal recessive|Spastic Paraplegia, Hereditary|*Autophagy|Autophagosomes|Retinal Degeneration|Mutations|Carrier Proteins|Endosomes|Proteins|Neurodegenerative Diseases|Amyotrophic Lateral Sclerosis|spastizin protein, human|TECPR2 protein, human|Nerve Tissue Proteins 18 TECPR2 23439247 Autophagy 2013 PMC3669195 10.4161/auto.23961 5 0 0 99 Humans|*Autophagy|Neurodegenerative Diseases|Paraparesis, Spastic|Lysosome|Nerve Tissue Proteins|Carrier Proteins|Mutation|Phenotype|Brain|TECPR2 protein, human 18 TRHDE 23825544 PLoS ONE 2013 PMC3692449 10.1371/journal.pone.0066569 21 5 6 27 Sheep|Animals|*Genome-Wide Association Study|*Phenotype|Single Nucleotide Polymorphisms|Quantitative Trait Loci|*Product, Meat|Body Weight 17 ATP5G3 23088660 Brain Pathol. 2012 10.1111/bpa.12002 27 1 2 115 Humans|*Autistic Disorder|*Down-Regulation|*Electron Transport|HEK293 Cells|*Brain|*Oxidative Phosphorylation|oligomycin sensitivity-conferring protein|Mitochondrial Proton-Translocating ATPases|Mitochondria|Gene Expression|Electron Transport Complex I|Oxidative Stress|Electron Transport Complex IV 17 C2orf40 22526622 Cell Tissue Res. 2012 PMC3367106 10.1007/s00441-012-1396-6 16 6 0 0 Humans|Male|Mice|Animals|*Tumor Suppressor Proteins|*Esophageal Cancer|*Oncogenes|Genes, Tumor Suppressor|Cell Movement|Cell Proliferation|Cell Line, Tumor|*B-Lymphocytes|Transfection|Cells, Epithelial 17 CPLANE1 23169490 Eur. J. Hum. Genet. 2012 PMC3722952 10.1038/ejhg.2012.254 25 0 4 15 Humans|Meckel syndrome type 1|*Arabs|*Genetic Heterogeneity|*Ciliary Motility Disorders|*Polycystic Kidney Diseases|*Encephalocele|*Retinitis Pigmentosa|*Abnormalities, Multiple|Ciliopathy|Mutation|DNA Mutational Analysis|*Genomics|Pedigree|Membrane Proteins|C5orf42 protein, human 19 CPLANE1 22425360 Am. J. Hum. Genet. 2012 PMC3322222 10.1016/j.ajhg.2012.02.011 38 2 7 15 Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Canada|*Mutations|Cerebellar Diseases|Homozygote|Exome|Pedigree|Membrane Proteins|Exon|Mutation, Missense|C5orf42 protein, human 19 CPLANE1 22264561 Neuromuscul. Disord. 2012 10.1016/j.nmd.2011.11.006 5 0 1 15 Humans|Male|Amyotrophy, monomelic|*Whole Exome Sequencing|*Exome|*Spinal Muscular Atrophies of Childhood|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Case-Control Studies|C5orf42 protein, human 19 GNB1L 22844420 PLoS ONE 2012 PMC3402462 10.1371/journal.pone.0040974 6 0 2 56 Animals|*Chickens|*Genome-Wide Association Study|*Genome Mapping|*Phenotype|Genome|Polymorphism, Single Nucleotide|Haplotype|Genotypes|Homozygote|Genomics|Heterozygote 17 GNB1L 22457764 PLoS ONE 2012 PMC3310870 10.1371/journal.pone.0033473 12 0 5 56 Humans|Leukocytes, Mononuclear|*Schizophrenia|Psychotic Disorders|*22q11 Deletion Syndrome|Chromosome Deletion|Genetic Predisposition to Disease|Networks, Gene|Neurons|Gene Expression|Genome|UFD1L protein, human 17 GNB1L 22326833 Am. J. Pathol. 2012 PMC3657620 10.1016/j.ajpath.2011.12.021 29 0 2 56 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Gene Deletion|DNA Copy Number Variations|*Hepatocyte|Hepatectomies|Liver Regeneration|PTPRD protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Gene Expression Regulation, Neoplastic|Cell Proliferation|DNA, Neoplasm|Transcription Factors|RSU1 protein, human|Rab1B protein, human|rab1 GTP-Binding Proteins|BAHCC1 protein, human|Proteins 17 IPO11 23216389 Alcohol. Clin. Exp. Res. 2012 PMC3610804 10.1111/acer.12032 25 3 0 123 Humans|*Nicotine|*Codependency, Psychological|Genome-Wide Association Study|European Continental Ancestry Group|Genetic Predisposition to Disease|African Americans|Alcohol Dependence|Polymorphism, Single Nucleotide|*Ethanol|HTR1A protein, human|*Receptor, Serotonin, 5-HT1A|Case-Control Studies|Membrane Proteins|IPO11 protein, human|beta Karyopherins 17 MIR486 22909992 Forensic Sci Int Genet 2012 10.1016/j.fsigen.2012.07.006 6 0 1 0 Humans|Female|*RNA, Micro|Saliva|*Biomarkers|Forensic Genetics|Body Fluids|Semen|Cervix Mucus|Quantitative Real Time Polymerase Chain Reaction|Blood Stains|Menstruation|MIRN138 microRNA, human 17 MYLK3 23095280 Circulation 2012 PMC3510779 10.1161/CIRCULATIONAHA.112.116202 47 13 4 162 myosin light chain 2|*Myosin Light Chains|*Phosphorylation|Cardiac Myosins|Myosin Light Chain Kinase|Cardiomyocytes|Myocardial Contraction|Cardiac Hypertrophy|Myocardium|Heart Failure|Heart Ventricles|*Adaptation, Physiological|*Acclimatization 17 MYLK3 22719074 Cardiovasc. Res. 2012 10.1093/cvr/cvs196 15 4 2 162 *Sarcomeres|*RNA, Micro|*Myocardial Contraction|Myocytes, Cardiac|Cardiac Myosins|Myocardium|Myosin-Light-Chain Kinase|Phosphorylation 17 MYO3B 22954581 Bioarchitecture 2012 PMC3696061 10.4161/bioa.21733 8 9 4 42 Chlorocebus aethiops|Animals|Myosin Type III|*Myosins|Stereocilia|Filopodia|Actin|Myosin Heavy Chains|Microfilament Proteins|COS Cells|*Biophysics 17 MYO3B 22264607 Curr. Biol. 2012 PMC3288355 10.1016/j.cub.2011.12.053 33 16 6 42 Humans|Animals|Chlorocebus aethiops|*Actins|*Myosin B|Myosin Type III|Filopodia|Stereocilia|Filaments, Actin|Myosin Heavy Chains|*Protein Binding|Microfilament Proteins|COS-7 Cell|Cell Movement|Hearing Loss|Deafness 17 NAGPA 22884963 Mol. Genet. Metab. 2012 PMC3483359 10.1016/j.ymgme.2012.07.020 0 0 0 19 Humans|Animals|Mice|*Stuttering|Mucolipidosis|Transferases (Other Substituted Phosphate Groups)|Mutations|Mutations, Missense|Phenotype|Phosphoric Diester Hydrolases|Lysosomes|GNPTG protein, human|GNPTAB protein, human 17 NKAIN2 22495107 Genomics 2012 10.1016/j.ygeno.2012.03.005 2 0 0 16 Humans|*Genome, Human|Alu Elements|Gene Conversion|Genomics|Sequence Analysis, DNA|Polymorphism, Genetic|Mutagenesis, Insertional|Evolution, Molecular|Computational Biology|PCR 17 POLR2M 22850672 EMBO J. 2012 PMC3433857 10.1038/emboj.2012.205 13 0 1 96 Animals|*Cryoelectron Microscopy|transcription factor TFIIF|Transcription Factors, TFII|RNA Polymerase II|Transcription, Genetic|Mediator Complex|Binding Sites|Transcription Factors|DNA-Directed RNA Polymerases|Promoter Regions, Genetic|*Mammals 17 POLR2M 22771989 Transcription 2012 PMC3654766 10.4161/trns.20600 5 0 0 96 Humans|*RNA Polymerase II|Transcription Elongation, Genetic|Transcription Factors, TFII|Transcription, Genetic|Models, Biological 17 POLR2M 22244332 Mol. Cell 2012 PMC3259531 10.1016/j.molcel.2011.12.014 36 50 3 96 *RNA Polymerase II|transcription factor TFIIF|Transcription Factors, TFII|Transcription, Genetic|*Gene Expression Regulation|Transcription Factors|Protein Binding|Cryoelectron Microscopy|Promoter Regions, Genetic 17 POLR2M 22244331 Mol. Cell 2012 PMC3259526 10.1016/j.molcel.2011.10.022 71 23 7 96 Humans|*RNA Polymerase II|Transcription Factors, TFII|P-TEFb|Transcription, Genetic|Transcriptional Elongation Factors|Transcription Factors|Promoter Regions, Genetic|HeLa Cells|POLR2M protein, human 17 POLR2M 22231121 Transcription 2012 PMC3265782 10.4161/trns.2.5.17803 24 0 3 96 Humans|*RNA Polymerase II|*Phosphorylation|*Protein Interaction Domain|Transcription, Genetic|Amino Acid Sequence|Protein Binding|Binding Sites|Cell Cycle Proteins|Promoter Regions, Genetic|RPAP2 protein, human|Carrier Proteins 17 RAB6C 22949199 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2012 PMC3433202 10.1107/S1744309112030874 1 0 0 56 *Crystallization|*X-Rays|*X Ray Crystallographies|Guanosine Triphosphate|rab GTP-Binding Proteins|Golgi Apparatus|Protein Transport|Isoforms 17 STXBP6 23192668 Lipids 2012 PMC3601742 10.1007/s11745-012-3740-8 18 6 3 29 Humans|Phenofibrate|*Lipoprotein|Postprandial Period|Hypolipidemic Agents|Triglycerides|*Nuclear Magnetic Resonance|SNPs|Cholesterol, HDL|Lipoproteins, HDL|Lipids|*Genetic Testing|Dietary Fats|Genotype|Lipid Metabolism|*Magnetic Resonance Imaging|NR5A2 protein, human|Receptors, Cytoplasmic and Nuclear|CRIPT protein, human 18 STXBP6 22685579 PLoS ONE 2012 PMC3369852 10.1371/journal.pone.0038539 7 4 0 29 Humans|*Tumor Necrosis Factor-alpha|Denmark|*Rheumatoid Arthritis|Antirheumatic Agents|Etanercept|Receptors, Tumor Necrosis Factor|Adalimumab|Infliximab|Antibodies, Monoclonal, Humanized|Antibodies, Monoclonal|Immunoglobulin G|*Immunologic Factors|Treatment Outcome|Severity of Illness Index|Qa-SNARE Proteins 18 STXBP6 22464253 Am. J. Hum. Genet. 2012 PMC3322228 10.1016/j.ajhg.2012.02.023 60 1 7 29 Humans|interferon regulatory factor-8|Genome-Wide Association Study|*Interferon Regulatory Factors|*Lupus Erythematosus, Systemic|Asian|Haplotype|European Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|African Americans|Hispanic|Alleles|Genotype|Case-Control Studies|ZPBP2 protein, human|Egg Proteins|Membrane Proteins|ADAMTSL1 protein, human 18 TECPR2 23176824 Am. J. Hum. Genet. 2012 PMC3516605 10.1016/j.ajhg.2012.09.015 38 0 2 99 Humans|*Paraparesis, Spastic|*Mutation|*Autophagy|Spastic Paraplegia, Hereditary|Neurodegenerative Diseases|Homozygote|Pedigree|Phenotype|Nerve Tissue Proteins|Carrier Proteins|Frameshift Mutation|TECPR2 protein, human 18 TRIM47 22795385 J. Neurol. Sci. 2012 PMC3484396 10.1016/j.jns.2012.06.016 0 0 0 68 *Genome-Wide Association Study|*White Matter|*Genetic Linkage|NOTCH3 protein, human|Receptor, Notch3|Leukoencephalopathies|Genetic Predisposition to Disease|Nerve Fibers, Myelinated|Renin-Angiotensin System|Receptors, Notch|Magnetic Resonance Imaging|Hypertension|*Nervous System Diseases 17 TRIM47 22735669 Exp. Gerontol. 2012 PMC3490100 10.1016/j.exger.2012.06.003 9 0 0 68 *Dementia, Vascular|NOTCH3 protein, human|Receptor, Notch3|Cerebral Small Vessel Disease|Receptors, Notch|Imaging, Magnetic Resonance|Brain|Genetic Linkage|Genetic Association Studies|Hypertension 17 C2orf40 22110708 PLoS ONE 2011 PMC3218004 10.1371/journal.pone.0027656 53 2 3 0 Humans|*Down-Regulation|Prognosis|Esophageal Neoplasms|Genes, Tumor Suppressor|Tumor Suppressor Proteins|Gene Expression Regulation, Neoplastic|Carcinoma|Cell Line, Tumor|Cell Proliferation|RNA, Messenger 17 CAMSAP1 22095662 J. Comp. Neurol. 2011 10.1002/cne.22788 4 0 0 94 Animals|Mice|*Astrocytes|*Spectrin|*Calmodulin|Glial Fibrillary Acidic Protein|NES protein, human|Nestin|Gliosis|Cell Lineage|*Synapsins|*Biomarkers|Cell Differentiation|Brain Injuries|Neuroglia|Stem Cells|Brain|Cerebral Cortex|Bromodeoxyuridine 17 DCLK2 21832240 Sci Transl Med 2011 10.1126/scitranslmed.3002464 117 0 11 159 Humans|*DNA Copy Number Variations|*Attention Deficit Disorder with Hyperactivity|Autism Spectrum Disorder|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|*Risk Factors|Gene Expression 17 GNB1L 22095694 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2011 PMC3270696 10.1002/ajmg.b.32002 8 1 0 56 Humans|*Autistic Disorder|Comparative Genomic Hybridization|Chromosome 22q11.2 Microduplication Syndrome|DiGeorge Syndrome|Chromosome Duplication|Phenotype|Pedigree|Chromosome Deletion|DNA Copy Number Variations|Gene Duplication|In Situ Hybridization, Fluorescence|Genetic Predisposition to Disease|Translocation, Genetic|DNA Sequencing|Chromosomes, Human, Pair 22 17 IPO11 21965294 Mol. Biol. Cell 2011 PMC3226482 10.1091/mbc.E11-03-0222 9 28 0 123 Humans|*Nuclear Localization Signals|*Active Transport, Cell Nucleus|Karyopherins|*RNA Transport|beta Karyopherins|Nucleocytoplasmic Transport Proteins|Cell Nucleus|Saccharomyces cerevisiae Proteins|RNA-Binding Proteins|RNA, Messenger|Binding Sites|Cytoplasm|NXF1 protein, human 17 MIR486 21848520 Br. J. Haematol. 2011 10.1111/j.1365-2141.2011.08817.x 4 0 0 0 Humans|Child, Preschool|Child|Chromosome 8, mosaic trisomy|*Mosaicism|Chromosome 8, partial trisomy|Chromosome 8, trisomy|*Trisomy|In Situ Hybridization, Fluorescence|Comparative Genomic Hybridization|*Leukemia, Myeloid|Leukemia, Myelomonocytic, Juvenile|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|*Germ Line|Chromosome 8|Uniparental Disomy 17 MIR486 21525938 Cell Death Dis 2011 PMC3122063 10.1038/cddis.2011.32 42 4 7 0 Humans|*Cell Survival|Sezary Syndrome|Mycosis Fungoides|Cutaneous T Cell Lymphoma|MicroRNAs|Prognosis|Gene Expression Regulation, Neoplastic|*Upregulation|Biomarkers, Tumor|Skin Neoplasms|Gene Expression Profiling|*Transcriptional Activation|Cohort Studies|Case-Control Studies|MIRN21 microRNA, human|MIRN214 microRNA, human|MIRN486 microRNA, human 17 NAGPA 22027460 Ned Tijdschr Geneeskd 2011 1 0 0 19 Child|Humans|*Stuttering|Speech Therapy|Treatment Outcome|Behavior Therapy|Mutation|Operant Conditioning|GNPTG protein, human|Transferases (Other Substituted Phosphate Groups)|GNPTAB protein, human 17 NAGPA 21956109 J. Biol. Chem. 2011 PMC3220557 10.1074/jbc.M111.295899 7 0 0 19 Humans|N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase|*Mannose|*Stuttering|*Phosphoric Diester Hydrolases|*Mutations|mannose-6-phosphate|Mannosephosphates|Transferases (Other Substituted Phosphate Groups)|Golgi Apparatus|Lysosomes|Mutation, Frame Shift|Phenotype|Hydrolases|Amino Acid Sequence|Phosphates 17 NAGPA 21850444 J Neurodev Disord 2011 PMC3261268 10.1007/s11689-011-9090-7 8 0 0 19 Humans|*Stuttering|Transferases (Other Substituted Phosphate Groups)|Mutations|Speech Disorders|mannose-6-phosphate|Mannosephosphates|Phosphoric Diester Hydrolases|Genetic Linkage|GNPTG protein, human|GNPTAB protein, human 17 NAGPA 21663442 Annu Rev Genomics Hum Genet 2011 10.1146/annurev-genom-090810-183119 17 0 2 19 Humans|Child|*Speech|*Language Disorders|Speech Disorders|Stuttering|Verbal Dyspraxia|Dyslexia|Pedigree|Genetic Linkage|Forkhead Transcription Factors|Language|Repressor Proteins|Mutations|GNPTG protein, human|Transferases (Other Substituted Phosphate Groups)|GNPTAB protein, human 17 NKAIN2 21445666 J Neural Transm (Vienna) 2011 10.1007/s00702-011-0628-3 12 0 0 16 Humans|*Alcoholism|Genome-Wide Association Study|Australia|SNPs|Genetic Predisposition to Disease|Genotype|Linkage Disequilibrium|European Continental Ancestry Group|Case-Control Studies|Pedigree|*Family Relations|Family Health 17 STXBP6 21738478 PLoS Genet. 2011 PMC3128095 10.1371/journal.pgen.1002067 38 3 4 29 Humans|Genome-Wide Association Study|Japan|European Continental Ancestry Group|*White Blood Cell|Leukocyte Count|Genetic Loci|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genetic Predisposition to Disease|African Americans|Phenotype|Neutrophils|Lymphocytes|Monocytes|SLC45a3 protein, human|Membrane Transport Proteins 18 TEFM 21278163 Nucleic Acids Res. 2011 PMC3105396 10.1093/nar/gkq1224 62 14 5 45 Humans|*mtDNA|*Mitochondria|Transcription, Genetic|RNA Polymerase|Mitochondrial Proteins|Transcription Factors|Mitochondrial RNA|Promoter Regions, Genetic|PTCD3 protein, human|RNA-Binding Proteins|Arabidopsis Proteins|TEFM protein, human 17 TRHDE 21452313 Arthritis Rheum. 2011 10.1002/art.30235 56 0 7 27 Humans|*Genome-Wide Association Study|Republic of Korea|*Rheumatoid Arthritis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genotype|Case-Control Studies|European Continental Ancestry Group 17 TRIM47 21681796 Ann. Neurol. 2011 PMC3122147 10.1002/ana.22403 0 0 8 68 *Genome-Wide Association Study|*White Matter|Brain|Leukoencephalopathies|Stroke|Genetic Loci|Imaging, Magnetic Resonance|Polymorphism, Single Nucleotide 17 BTBD7 20671187 Science 2010 PMC3412157 10.1126/science.1191880 56 9 1 55 Animals|Pregnancy|Female|*Morphogenesis|*Epithelial Cell|Salivary Glands|CDH1 protein, human|E Cadherin|Cell Adhesion|Cell Motility|Extracellular Matrix|Submandibular Gland|Gene Expression Regulation, Developmental|Fibronectins|Embryonic Development|Mammalian Embryos|Lungs|Antigens, CD 17 FAM172A 21092515 Zhonghua Yi Xue Za Zhi 2010 1 2 0 42 Humans|*HEK293 Cells|*Apoptosis|Transfection|Genetic Vectors|Cell Proliferation|Plasmids|Cell Line, Tumor|Cell Cycle|*Proteins|FAM172A protein, human 17 FAM172A 20818486 Int. J. Mol. Med. 2010 5 2 0 42 Animals|Humans|Rabbits|*Up-Regulation|HEK293 Cells|*Smooth Muscle Cells|*Aorta|Muscle, Smooth, Vascular|Amino Acid Sequence|Cloning, Molecular|Recombinant Proteins|*Transcriptional Activation|RNA, Messenger|Open Reading Frame|*Tunica Media|Sequence Homology, Amino Acid|Glucose|FAM172A protein, human|Proteins 17 FAM172A 20137623 Zhonghua Yi Xue Za Zhi 2010 4 3 0 42 *Cloning, Molecular|Amino Acid Sequence|Proteins|Base Sequence|DNA, Complementary|Gene Expression|Open Reading Frames|RNA, Messenger|Sequence Analysis, DNA|*Diabetes Mellitus 17 FANK1 20978819 Cell. Mol. Life Sci. 2010 10.1007/s00018-010-0559-4 13 7 1 22 *Transcription Factor AP-1|COP9 Signalosome Complex|Intracellular Signaling Peptides and Proteins|Proto-Oncogene Proteins c-jun|*Apoptosis|Signal Transduction|Two-Hybrid System Techniques|Transcriptional Activation|Protein Binding|Phosphorylation|Peptide Hydrolases|Cell Line 17 GNB1L 20538345 Psychiatry Res 2010 10.1016/j.psychres.2010.04.019 5 0 1 56 Humans|Depressive Disorder, Major|*Asian Continental Ancestry Group|Bipolar Disorder|Schizophrenia|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Gene Frequency|Haplotypes|Genotype|Case-Control Studies 17 MYLK3 20100464 Biochem. Biophys. Res. Commun. 2010 10.1016/j.bbrc.2010.01.076 30 0 2 162 Mice|Humans|Rats|Animals|*Heart Failure|*Gene Expression Profiling|Myocardium|Cardiomyocytes|Oligonucleotide Array Sequence Analysis 17 NAGPA 20147709 N. Engl. J. Med. 2010 PMC2936507 10.1056/NEJMoa0902630 48 0 3 19 *Stuttering|*Mutations|Mucolipidoses|Transferases (Other Substituted Phosphate Groups)|Genetic Predisposition to Disease|*Lysosomes|Phosphoric Diester Hydrolases|*Hydrolases 17 NKAIN2 20634892 PLoS ONE 2010 PMC2901337 10.1371/journal.pone.0011504 31 0 0 16 *Genome-Wide Association Study|*Neuroticism|SNPs|Genetic Predisposition to Disease|Neurotic Disorders|Genotype|Anxiety Disorders|Depressive Disorder, Major|Phenotype|Personality Disorders|Personality 17 POLR2M 20412299 FEBS J. 2010 10.1111/j.1742-4658.2010.07649.x 5 2 0 96 Humans|*Dyneins|*Glutamate|Cytoplasmic Dyneins|Protein Structure, Tertiary|Amino Acid Sequence|Binding Sites|Carrier Proteins|Protein Binding|Membrane Proteins|Microtubules|Cytoplasm|Models, Molecular|NOS1 protein, human|Neuronal Nitric Oxide Synthase|Dimerization 17 RAB6C 20064528 J. Mol. Biol. 2010 10.1016/j.jmb.2010.01.009 27 1 3 56 Humans|Animals|rab GTPases|Golgi Apparatus|Protein Transport|Guanosine Triphosphate|Endoplasmic Reticulum|Amino Acid Sequence|Biological Transport|HeLa Cells|*Cell Division 17 RAPGEF5 20110292 Ann. Oncol. 2010 PMC2813308 10.1093/annonc/mdp520 16 2 0 1596 Humans|*Carcinoma, Non-Small-Cell Lung|*Erlotinib Hydrochloride|*Biomarkers, Tumor|*Lung Neoplasms|Quinazolines|ErbB Receptors|Protein Kinase Inhibitors|Antineoplastic Agents|ras Proteins|Disease-Free Survival|*Gene Expression Profiling|Antineoplastic Combined Chemotherapy Protocols|Mutation|Kaplan-Meier Estimate 17 STXBP6 20193695 Mutat. Res. 2010 PMC2872054 10.1016/j.mrfmmm.2010.02.007 11 18 0 29 Humans|*DNA Methylation|*B-DNA|CpG Islands|Epigenesis, Genetic|Cell Transformation, Neoplastic|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Line, Tumor|Oestradiol|Downregulation|NRG1 protein, human|Neuregulin-1|Estrogens|Epithelial Cell|Transcription Initiation Site 18 STXBP6 20071347 Hum. Mol. Genet. 2010 10.1093/hmg/ddq013 36 0 2 29 Humans|Animals|Mice|*Autistic Disorder|NBEA protein, human|*Nerve Tissue Proteins|*Carrier Proteins|Cell Adhesion Molecules, Neuronal|Membrane Proteins|Genetic Predisposition to Disease|Brain|Chromosomal Translocation|CLIC4 protein, human|Chloride Channels|SCAMP5 protein, human 18 SYNM 20543860 Oncogene 2010 10.1038/onc.2010.229 21 3 2 1214 Humans|desmuslin|Epigenesis, Genetic|*Intermediate Filaments|Neoplasm Recurrence, Local|*Promoter Regions, Genetic|*Intermediate Filament Proteins|DNA Methylation|Gene Expression Regulation, Neoplastic|DNA, Neoplasm|mRNA|Downregulation|Gene Silencing|Cell Line, Tumor 17 CAMSAP1 19508979 Mol. Biol. Evol. 2009 10.1093/molbev/msp115 35 2 8 94 Animals|Humans|Rats|HeLa Cells|*Microtubules|Microtubule-Associated Proteins|Spectrin|Neurites|Calmodulin|Amino Acid Sequence|Drosophila|PC12 Cells|Sequence Homology, Amino Acid|Protein Binding|*Biophysical Phenomena 17 DCLK2 19342486 Proc. Natl. Acad. Sci. U.S.A. 2009 PMC2672532 10.1073/pnas.0812687106 33 0 0 159 Humans|Animals|Mice|doublecortin protein|*Hippocampus|Neuropeptides|*Neurons|Microtubule-Associated Proteins|Mice, Knockout|Neocortex|Epilepsy|Cell Movement|*Seizures 17 GNB1L 19737746 Genetics 2009 PMC2778960 10.1534/genetics.109.107722 24 0 2 56 Humans|Allele Frequency|Haplotypes|Genetics, Population|Linkage Disequilibrium|Genotype|Selection, Genetic|HapMap|SNPs|Genetic Variation|Genome, Human|Human Genome Diversity Project|Homozygote 17 GNB1L 19268070 Rev Esp Cardiol 2009 10.1016/s1885-5857(09)71555-5 0 0 0 56 Humans|*Heart Septal Defects, Ventricular|*Loss of Heterozygosity|Heart Defects, Congenital|Microsatellite|Chromosome Deletion 17 IPO11 19819847 Yi Chuan 2009 10.3724/sp.j.1005.2009.00941 1 0 0 123 Male|Female|Pregnancy|Mice|Animals|*Tripterygium|*Spermiogenesis|Testis|Glycosides|Drugs, Chinese Herbal|Reproduction|HERC4 protein, mouse|Ubiquitin-Protein Ligases 17 MYO3B 19332056 Exp. Eye Res. 2009 PMC2782900 10.1016/j.exer.2009.03.011 6 0 0 42 Humans|Mice|Animals|Myosin III|*Retinal Cone Photoreceptor Cells|*Myosin|Retina|Opsin, Cone|Myosin Heavy Chains|Amino Acid Sequence|Eye Proteins|Hair Cells, Auditory|Cloning, Molecular|MYO3A protein, mouse|MYO3B protein, mouse 17 STXBP6 19933552 Toxicol Pathol 2009 PMC2907875 10.1177/0192623309354108 42 10 2 29 Humans|*Estrogens|bisphenol A|Benzhydryl Compounds|Phenols|butylbenzyl phthalate|Phthalic Acids|Estradiol|Endocrine Disrupting Chemicals|DNA Methylation|Cell Transformation, Neoplastic 18 ATP5G3 18505769 Physiol. Genomics 2008 10.1152/physiolgenomics.90201.2008 18 0 1 115 Humans|*Transcriptome|Endothelial Cells|*Vascular Endotheliums|Gene Expression Regulation|Stress, Mechanical|Transcription, Genetic|Gene Expression Profiling|Genes, cdc|RNA, Messenger|Artery, Coronary|endothelial PAS domain-containing protein 1|Basic Helix-Loop-Helix Transcription Factors|Cells, Cultured|EFEMP1 protein, human|Extracellular Matrix Proteins|Heme Oxygenase-1|LOXL2 protein, human|Amino Acid Oxidoreductases 17 ATP5G3 18445752 Am. J. Physiol. Endocrinol. Metab. 2008 10.1152/ajpendo.90255.2008 9 1 3 115 Humans|Male|Aged|Oxygen Consumption|Exercise Test|Exercise Training|Physical Fitness|Muscle, Skeletal|Oxidative Phosphorylation|Aging|Oxygen|ETHE1 protein, human|Mitochondrial Proteins|Nucleocytoplasmic Transport Proteins 17 CAMSAP1 18756519 J. Neurosci. Res. 2008 10.1002/jnr.21853 3 0 0 94 Animals|Rats|Mice|*Astrocytes|*Spectrin|*Calmodulin|Glial Fibrillary Acidic Protein|Neuroglia|Cell Lineage|*Synapsins|Stem Cells|Neurons|Nestin|Vimentin|Cell Differentiation|Cells, Cultured|Neurogenesis|*Antibodies, Monoclonal|Intermediate Filament|Ependyma|Immunohistochemistry 17 FANK1 18682798 PLoS ONE 2008 PMC2488373 10.1371/journal.pone.0002907 10 0 2 22 Humans|Child|*Asthma|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Hypersensitivity, Immediate|Genome-Wide Association Study|Genotype|Genetic Association Studies|Phenotype|Cohort Studies|ADAM8 protein, human|Membrane Proteins|ADAM Proteins 17 GNB1L 19011233 Schizophr Bull 2008 PMC2894596 10.1093/schbul/sbn160 9 1 0 56 Humans|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Intracellular Signaling Peptides and Proteins|Gene Expression|Chromosome Deletion|Cortex, Prefrontal 17 GNB1L 18636634 Dev Disabil Res Rev 2008 10.1002/ddrr.5 25 0 2 56 Adult|Humans|Child|Male|Mice|Animals|*DiGeorge Syndrome|COMT protein, human|Catechol O-Methyltransferase|Psychosis|Shprintzen Golberg craniosynostosis|*Arachnodactyly|Schizophrenia|Proline Dehydrogenase|*Marfan Syndrome|*Craniosynostoses|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Endophenotype|Chromosome Deletion 17 POLR2M 18849881 Neuroreport 2008 10.1097/WNR.0b013e328317f05f 4 2 1 96 Animals|Rats|Humans|*N Methyl D aspartate|*D-Aspartic Acid|HEK293 Cells|aspartic acid receptor|*Receptors, N-Methyl-D-Aspartate|Neurons|Hippocampus|Cerebral Cortex 17 RAB6C 18992151 BMC Cancer 2008 PMC2588621 10.1186/1471-2407-8-327 7 8 1 56 *Tumor Suppressor Protein p53|DNA Methylation|Drug Resistance, Multiple|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Drug Resistance, Neoplasm|ATP Binding Cassette Transporter, Subfamily B, Member 1|Transfection|Antineoplastic Agents|rab GTP-Binding Proteins 17 ATP5G3 17316384 Differentiation 2007 10.1111/j.1432-0436.2006.00118.x 8 4 1 115 Rats|Animals|Muscle Atrophy|Muscle Fibers, Slow-Twitch|Muscle Fibers, Fast-Twitch|*Soleus Muscle|Hindlimb Suspension|Myosin Heavy Chains|Space Flight|Immobilization|Hindlimbs 17 CAMK2N2 17350603 Brain Res. 2007 10.1016/j.brainres.2007.02.018 4 0 1 46 Animals|Mice|*Calmodulin|*Neurons|Calcium-Calmodulin-Dependent Protein Kinase Type 2|Amino Acid Sequence|Brain|mRNA|Recombinant Proteins 17 DCLK2 18075264 Dev. Neurosci. 2007 10.1159/000109861 7 0 0 159 Humans|Animals|Mice|doublecortin protein|*Mice, Knockout|Microtubule-Associated Proteins|Neuropeptides|Neurons|Neocortex|Nerve Tissue Proteins|Cell Movement|In Situ Hybridization|Gene Expression Regulation, Developmental|Region, Hippocampal CA3|Protein-Serine-Threonine Kinases|DCLK1 protein, human|Intracellular Signaling Peptides and Proteins 17 FANK1 17604233 Gene Expr. Patterns 2007 10.1016/j.modgep.2007.05.005 9 0 0 22 Humans|Male|Mice|Animals|*Testis|*Nuclear Protein|*Haploidy|*Spermatogenesis|Spermatids|Spermatocytes|Transcription Factor|Meiosis|Amino Acid Sequence|Gene Expression Regulation, Developmental|mRNA|In Situ Hybridization|Cloning, Molecular|Fank1 protein, human|DNA-Binding Proteins 17 GNB1L 18003636 Hum. Mol. Genet. 2007 10.1093/hmg/ddm330 23 0 4 56 Male|Animals|Mice|*Schizophrenia|Psychosis|SNPs|Genotype|Genetic Predisposition to Disease|Alleles|DiGeorge Syndrome|Haplotypes|Genetic Linkage|Chromosome Deletion|Gene Expression|T-Box Domain Proteins|Case-Control Studies|Bulgaria 17 POLR2M 17317662 Mol. Cell Proteomics 2007 10.1074/mcp.M600297-MCP200 41 0 1 96 Humans|HEK293 Cells|Initiation Codon|Open Reading Frames|Protein Biosynthesis|5' Untranslated Regions|mRNA|Ribosomes|Base Sequence|Alternative Splicing|Amino Acid Sequence|cDNA|Exons|Proteome|Proteomics 17 RAB6C 17426708 Br. J. Cancer 2007 PMC2359938 10.1038/sj.bjc.6603724 7 13 0 56 TP53 protein, human|*Tumor Suppressor Protein p53|Promoter Regions, Genetic|Multidrug Resistance|Gene Expression Regulation, Neoplastic|Transgene|Transcriptional Activation|Transcription Factor|Epigenesis, Genetic|Base Sequence|Transfection|Binding Site|Tumor Cells, Cultured|rab GTP-Binding Proteins 17 RAPGEF5 17491018 J. Biol. Chem. 2007 10.1074/jbc.M700128200 39 3 1 1596 Humans|*Chemotaxis|Endothelial Cells|*Anthrax|Guanine Nucleotide Exchange Factors|Cyclic AMP|rap1 GTP-Binding Proteins|Signal Transduction|Cyclic AMP-Dependent Protein Kinases|anthrax toxin|*Bacterial Toxins|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|*Antigens, Bacterial|Colforsin|Cyclase, Adenylyl|erythromycin propionate-N-acetylcysteinate|*Acetylcysteine|*Erythromycin 17 ZNF146 18000824 Int. J. Cancer 2007 10.1002/ijc.23258 14 0 0 42 *Proteomics|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Barrett Esophagus|Biomarkers, Tumor|Cell Transformation, Neoplastic|mRNA|Gene Expression Profiling|LGI1 protein, human|Proteins|Two Dimensional Gel Electrophoresis 17 ATP5G3 16803979 Ann. N. Y. Acad. Sci. 2006 10.1196/annals.1354.017 0 0 0 115 Rats|Animals|*Myocardium|Blotting, Northern|*Heart Ventricles|Heart|Gene Expression Regulation|RNA|Gene Expression|RNA, Messenger|Gene Expression Profiling|cDNA|Aging|DNA Primers|Upregulation|Proteins|Downregulation 17 CAMK2N2 17038644 Circ. Res. 2006 10.1161/01.RES.0000249369.71709.5c 34 4 0 46 Mice|Animals|*Action Potentials|*Up-Regulation|Renal Dialysis|Sarcoplasmic Reticulum|CaM KII|phospholamban|Calcium-Binding Proteins|Myocytes, Cardiac|Ryanodine Receptor Calcium Release Channel|Calcium|Myocardium|Myocardial Contraction|Whole-Cell Recordings|Phosphorylation|*Transcriptional Activation 17 CAMK2N2 17010311 Biochem. Biophys. Res. Commun. 2006 10.1016/j.bbrc.2006.09.066 2 0 0 46 Male|Animals|Mice|Rats|*Calmodulin|Calcium-Calmodulin-Dependent Protein Kinase Type 2|Encephalitis, Japanese|Brain|mRNA|Japanese Encephalitis Virus|Isoforms|Up-Regulation|Amino Acid Sequence|invariant chain|*Histocompatibility Antigens Class II 17 CAMK2N2 16861697 Am. J. Physiol. Heart Circ. Physiol. 2006 10.1152/ajpheart.00353.2006 70 6 0 46 Mice|Animals|Sarcoplasmic Reticulum|CaM KII|phospholamban|Calcium-Binding Proteins|Myocytes, Cardiac|Ryanodine Receptor Calcium Release Channel|Isoproterenol|Myocardium|Myocardial Contraction|Calcium|*Apoptosis|Cyclic AMP-Dependent Protein Kinases|Phosphorylation|*Protective Agents 17 GNB1L 16684884 Proc. Natl. Acad. Sci. U.S.A. 2006 PMC1472513 10.1073/pnas.0600206103 109 2 3 56 Child|Mice|Humans|Animals|*Haploinsufficiency|*22q11 Deletion Syndrome|Velocardiofacial Syndrome|T-Box Domain Proteins|Phenotype|Schizophrenia|Chromosome Deletion|Mutation|TBX1 protein, human|Tbx1 protein, mouse 17 TRHDE 16543368 Endocrinology 2006 10.1210/en.2006-0160 15 1 0 27 Humans|Male|Mice|Animals|*Receptors, Thyrotropin|*Mice, Inbred BALB C|*Mice, Inbred C57BL|thyrotropin-binding inhibitory immunoglobulin|*Immunoglobulins, Thyroid-Stimulating|*Hyperthyroidism|Graves Disease|*Immunizations|Thyroid Gland|*Vaccination|Thyroxine|Adenovirus|Autoantibodies|Genetic Linkage|Disease Models, Animal 17 ZNF146 16595896 Biol. Pharm. Bull. 2006 10.1248/bpb.29.655 7 0 2 42 Humans|*Toxicogenetics|kojic acid|Melanoma, Cutaneous Malignant|Melanoma|Cancer, Skin|*Gene Expression Profiling|*Pyrones|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Up-Regulation|Gene Expression|Real-Time PCR, Quantitative 17 ATP5G3 15979584 Biochem. Biophys. Res. Commun. 2005 10.1016/j.bbrc.2005.06.047 3 0 0 115 Humans|*RNA Interference|Radiation Tolerance|Radiation Injuries|Gene Expression Profiling|Genes, cdc|Neoplasms 17 ATP5G3 15682396 J. Comp. Neurol. 2005 PMC2967457 10.1002/cne.20429 30 0 1 115 Mice|Animals|*Olfactory Receptor Neurons|Olfactory Epithelium|Olfactory Marker Protein|Receptors, Odorant|Olfactory Bulb|Axons|Nerve Tissue Proteins|In Situ Hybridization|Cilia|Cell Differentiation|RNA, Messenger|*Phenotypes|Reg3g protein, mouse|Pancreatitis-Associated Proteins 17 FANK1 15803458 Mol. Reprod. Dev. 2005 10.1002/mrd.20282 4 0 0 22 Cattle|Animals|Mice|*Oocytes|Blastocyst|*Reverse Transcriptase Polymerase Chain Reaction|Embryo, Mammalian|Embryonic Development|Gene Expression Regulation, Developmental|Expressed Sequence Tags|Gene Expression Profiling|Metaphase|RNA, Messenger|Base Sequence|Transcriptional Activation|*Genetic Techniques 17 NKAIN2 16145689 Hum. Mutat. 2005 10.1002/humu.20235 17 0 0 16 Humans|Mice|Animals|*Translocation, Genetic|*Phenotype|Chromosome Breakage|Base Sequence|In Situ Hybridization, Fluorescence|Amino Acid Sequence|Chromosome|Membrane Proteins 17 NKAIN2 15908570 J. Med. Genet. 2005 PMC2564632 10.1136/jmg.2004.029660 13 0 0 16 Child|Humans|Male|Adult|Mice|Animals|Translocation, Genetic|Chromosome Breakage|Fluorescent in Situ Hybridization|Cytogenetic Analysis|Base Sequence|Amino Acid Sequence|Intron|Genome, Human|*Infections 17 RAB6C 16267028 Cancer Res. 2005 10.1158/0008-5472.CAN-05-1944 6 2 0 56 Humans|*Epigenesis, Genetic|*Antineoplastic Agents|Multidrug Resistance|DNA Methylation|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Doxorubicin|Cell Line, Tumor|trichostatin A|Hydroxamic Acids|Transgene|rab GTP-Binding Proteins 17 RAB6C 16103095 Cancer Res. 2005 10.1158/0008-5472.CAN-05-0658 3 0 0 56 Humans|*MCF-7 Cells|Multidrug Resistance|DNA Methylation|Promoter Regions, Genetic|CpG Island|Gene Expression Regulation, Neoplastic|Doxorubicin|Tumor Cells, Cultured|Transgenes|rab GTP-Binding Proteins|Transfection|Downregulation|Nuclear Proteins 17 STXBP6 16033762 J. Biol. Chem. 2005 10.1074/jbc.M505858200 16 3 0 29 Animals|Rats|*Syntaxin|*Exocytosis|Syntaxin 1|Vesicle-Associated Membrane Protein|Chromaffin Cells|Vesicular Transport Proteins|Synaptosomal-Associated Protein 25|Nerve Tissue Proteins|Carrier Proteins|PC12 Cells|Cell Membrane|Amino Acid Sequence|Transfections|Cytoplasm 18 ZNF146 15881673 Mol. Cell. Biochem. 2005 10.1007/s11010-005-6417-2 2 0 0 42 Humans|ubiquitin-conjugating enzyme UBC9|HeLa Cells|*Sumoylation|*Zinc Finger Motifs|Ubiquitin-Conjugating Enzymes|SUMO-1 Protein|DNA-Binding Proteins|*Genes, Regulator|Transcription Factors|Two-Hybrid System Techniques|Protein Binding|Saccharomyces cerevisiae 17 ZNF146 15838871 J. Cell. Biochem. 2005 10.1002/jcb.20487 4 4 0 42 Humans|*Telomeres|HeLa Cells|*Zinc Finger|Telomere Repeat Binding Factor|*Transcription Factors|Telomeric Repeat Binding Protein 2|TYRP1 protein, human|*Membrane Glycoproteins|Amino Acid Sequence|Protein Binding|Saccharomyces cerevisiae|Immunoprecipitation|Colon 17 CAMK2N2 14755690 J. Cell. Biochem. 2004 10.1002/jcb.10751 10 3 0 46 Humans|*Mitogen-Activated Protein Kinases|*PI-3K|*Proto-Oncogene Proteins c-akt|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Signal Pathways|Mitogen-Activated Protein Kinase 1|Phosphoinositide-3 Kinase Inhibitors|Apoptosis|*Cell Death|Proto-Oncogene Proteins|MAP Kinase Signaling System|*Lung Adenocarcinoma|Chromones|JNK Mitogen-Activated Protein Kinases|p38 Mitogen-Activated Protein Kinases|Enzyme Inhibitors|*Doxorubicin 17 DCLK2 15611072 J. Biol. Chem. 2004 10.1074/jbc.M411027200 8 0 0 159 Animals|Chlorocebus aethiops|doublecortin protein|Microtubule-Associated Proteins|*Axons|Neuropeptides|Neurons|*Myosin-Light-Chain Kinase|Phosphorylation|Microtubules|Protein-Serine-Threonine Kinases|Growth Cones|Transfection|DNA, Complementary|Nerve Tissue Proteins|Cytoskeleton|Gene Expression Regulation, Developmental|Protein Binding|mRNA|Amino Acid Sequence 17 IPO11 15545318 J. Cell Biol. 2004 PMC2172591 10.1083/jcb.200406001 36 22 2 123 Humans|Mice|Animals|*Ubiquitin-Conjugating Enzymes|*Active Transport, Cell Nucleus|UBB protein, human|*Ubiquitin|Ubiquitin-Protein Ligases|Cell Nucleus|Protein Binding|Carrier Proteins 17 POLR2M 15233991 Genomics 2004 10.1016/j.ygeno.2004.04.004 19 1 2 96 Humans|*Eukaryotes|Exons|Alternative Splicing|Base Sequence|Transcription, Genetic|Transcription Factors|DNA, Complementary|Amino Acid Sequence|RNA Splicing|RNA, Messenger|DNA|Genome|*Chromosome Structures|Sequence Analysis, DNA 17 TRIM47 15003446 J. Mol. Biol. 2004 10.1016/j.jmb.2004.01.027 20 0 0 68 *Synthetase, Aminoacyl-tRNA|*Escherichia coli|Glutamyl-tRNA Synthetase|Escherichia coli Proteins|Anticodon|tRNAGlu|tRNA|*RNA|Amino Acid Sequence|Glutamate|RNA, Transfer, Asp|Thermus thermophilus|Crystallography, X-Ray|Substrate Specificity|Models, Molecular|Amino Acids 17 CAMK2N2 12824452 J. Physiol. (Lond.) 2003 PMC2343155 10.1113/jphysiol.2003.042002 14 0 0 46 Mice|Animals|*Calcium|Sarcoplasmic Reticulum|Muscle Contraction|Ryanodine Receptor Calcium Release Channel|Calcium-Calmodulin-Dependent Protein Kinase Type 2|Muscle, Skeletal|Myocytes, Cardiac|Calcium-Binding Proteins|Phosphorylation 17 IPO11 12767927 Biochem. Biophys. Res. Commun. 2003 10.1016/s0006-291x(03)00876-3 3 1 0 123 Humans|Male|Female|leucine-rich repeat proteins|Amino Acid Sequence|Repetitive Sequences, Amino Acid|*Cytokines|Protein Structure, Tertiary|Leucine|Cloning, Molecular|Membrane Proteins|Toll-Like Receptors 17 MYO3B 12631723 Mol. Biol. Cell 2003 PMC151579 10.1091/mbc.e02-06-0317 27 0 4 42 Animals|Chlorocebus aethiops|Male|*Myosin III|*Retinal Cone Photoreceptor Cells|*Myosin|*Retina|ATP-G-actin|Actins|Myosin Heavy Chains|Actin Cytoskeleton|Pseudopodia|Photoreceptors, Vertebrate|*Vertebrate|Amino Acid Sequence|Isoforms|COS Cells|Adenosine Triphosphate 17 RAPGEF5 14643017 Brain Res. Dev. Brain Res. 2003 10.1016/j.devbrainres.2003.09.017 2 1 0 1596 Humans|Mice|Animals|Rats|*Guanine Nucleotide Exchange Factor|*Telencephalon|*Cell Differentiation|*Neurons|Transcription Factor|LIM-Homeodomain Proteins|Homeodomain Proteins|Interneurons|Nerve Tissue Proteins|Progenitor Cells|RASGRF1 protein, human|*ras-GRF1|Embryo, Mammalian|Gene Expression Regulation, Developmental|Cell Movement|Cerebral Cortex|Cells, Cultured 17 TRIM47 14534135 Development 2003 10.1242/dev.00790 40 0 3 68 Animals|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Spindle Apparatus|*Signal Transduction|Anaphase|Asymmetric Cell Division|Cell Cycle Proteins|Cell Polarity|NCOA1 protein, human|*Nuclear Receptor Coactivator 1|Embryo, Nonmammalian|Cell Nucleus|LET-99 protein, C elegans|Mes-1 protein, C elegans|PAR-3 protein, C elegans|Protein-Serine-Threonine Kinases 17 ZNF146 12754738 J. Pathol. 2003 10.1002/path.1337 3 0 0 42 Animals|Mice|*Colorectal Cancer|*Colon Cancers|Adenomas|*Zinc Finger|Colon|TNM Classification|RNA, Neoplasm|Adenocarcinoma|Neoplasm Proteins|Carcinomas|Gene Expression Regulation, Neoplastic|Immunohistochemistry|Disease Progression|Intestinal Mucosa|Blotting, Western 17 MYO3B 11991710 Genomics 2002 10.1006/geno.2002.6749 17 0 3 42 Humans|Male|Animals|*Bardet-Biedl Syndrome|*Myosin A|Drosophila melanogaster|Myosin III|*Retina|Sequence Alignment|Exons|Amino Acid Sequence|Base Sequence|Protein Isoforms|cDNA|Myosin|Chromosome Mapping|Introns|Cloning, Molecular|Sequence Homology, Amino Acid|Myosin Heavy Chains|Sequence Analysis, DNA 17 NKAIN2 11979551 Genes Chromosomes Cancer 2002 10.1002/gcc.10057 8 0 0 16 In Situ Hybridization, Fluorescence|*Cell Lineage|*Cytogenetic Analysis|Translocation, Genetic|*Cytogenetic|Chromosome Breakage|Chromosome Banding|Oncogene Proteins, Fusion|Chromosome Aberrations|DNA-Binding Proteins|Adult T-Cell Leukemia|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Clones|*T Cell Lymphoma|Cell Line 17 RAB6C 12007787 Biochim. Biophys. Acta 2002 10.1016/s0167-4889(02)00164-7 8 3 0 56 Humans|*Multidrug Resistance|Doxorubicin|Antineoplastic Agents|Drug Resistance, Neoplasm|ATP Binding Cassette Transporter, Subfamily B, Member 1|DNA Methylation|Transfections|Cell Line, Tumor|Taxol|Gene Expression Regulation, Neoplastic|Vinblastine|Etoposide|Transgene|Sarcoma|Vincristine|rab GTP-Binding Proteins 17 STXBP6 12145319 J. Biol. Chem. 2002 10.1074/jbc.M204929200 20 2 0 29 Animals|Rats|*Syntaxin Protein|*Binding Protein|*Membrane Fusion|SNAP25 protein, human|Synaptosomal-Associated Protein 25|Syntaxin-1A|R-SNARE Proteins|Exocytosis|Vesicular Transport Proteins|Nerve Tissue Proteins|*Protein Binding|Amino Acid Sequence|PC12 Cells|Sequence Homology, Amino Acid|Binding Sites|*Biological Transport|Antigens, Surface 18 ZNF146 12437081 Transgenic Res. 2002 10.1023/a:1020347123109 0 0 0 42 Female|Mice|Animals|*Mice, Transgenic|Mammary Glands, Animal|Lactation|beta-Casein|Milk Proteins|Transgene|Zinc Finger Motifs|RNA, Messenger|Phenotype|*Organogenesis 17 ATP5G3 11459924 Physiol. Genomics 2001 10.1152/physiolgenomics.2001.6.2.91 13 0 0 115 Humans|Male|Rats|Animals|ATP synthase subunit 9, rat|*Mitochondrial Proton-Translocating ATPases|*Ethanol|*Up-Regulation|*Rats, Wistar|*Pancreas|Pancreatitis, Alcoholic|Ceruletide|*Transcriptional Activation|Display, mRNA Differential|Mitochondria|RNA, Messenger|cDNA|Cloning, Molecular 17 BTBD7 11527404 Biochem. Biophys. Res. Commun. 2001 10.1006/bbrc.2001.5478 2 0 0 55 Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Mice, Nude|*Liver Neoplasms|*NIH 3T3 Cells|cDNA Microarray|Transfections|cDNA|Liver|Cell Line, Tumor|Neoplasm Transplantation|Cell Nucleus|Cell Transformation, Neoplastic|Cell Proliferation 17 CAMK2N2 11444830 Biochem. Biophys. Res. Commun. 2001 10.1006/bbrc.2001.5175 10 0 0 46 Humans|Animals|Rats|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|*Cloning, Molecular|Amino Acid Sequence|cDNA Library|Northern Blot|DNA, Complementary|Transfection|*Calcium, Dietary|Up-Regulation|Cell Lines|RNA, Messenger|Sequence Homology, Amino Acid|Dendritic Cells 17 CAMK2N2 11182241 Neuroscience 2001 10.1016/s0306-4522(00)00520-0 40 0 0 46 Male|Animals|Rats|Mice|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|*Isoforms|Amino Acid Sequence|Brain|Phosphorylation|Base Sequence|In Situ Hybridization|*Calcium, Dietary|Neurons|Cerebellum|Cloning, Molecular|RNA, Messenger|Hippocampus 17 GNB1L 11709542 Hum. Mol. Genet. 2001 10.1093/hmg/10.22.2549 34 0 0 56 Humans|Animals|Mice|*DiGeorge Syndrome|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Marfan Syndrome|*Craniosynostoses|*Ear, Inner|Abnormalities, Multiple|Cardiovascular Abnormalities|Cell Cycle Proteins|Mice, Transgenic|*Chromosome Structures|In Situ Hybridization, Fluorescence 17 GNB1L 11350118 Genomics 2001 10.1006/geno.2000.6506 2 0 0 56 Humans|Mice|Animals|*DiGeorge Syndrome|*WD40 Repeats|Base Sequence|Amino Acid Sequence|Schmid-Fraccaro syndrome|*Chromosomes, Human, Pair 22|Chromosome Mapping|Proteins|Exons|DNA, Complementary|Sequence Homology, Amino Acid|Trisomy|Shprintzen Golberg craniosynostosis|Arachnodactyly|Aneuploidy|Eye Abnormalities|Craniosynostoses|Marfan Syndrome 17 TRIM47 11511098 Biochem. Biophys. Res. Commun. 2001 10.1006/bbrc.2001.5431 4 0 0 68 *Astrocytoma|Genes, Tumor Suppressor|Carrier Proteins|Amino Acid Sequence|Brain|Cloning, Molecular|DNA, Complementary|Genetic Techniques|Immunohistochemistry 17 ZNF146 11306801 Cytogenet. Cell Genet. 2001 10.1159/000056873 0 0 0 42 Humans|*Promoter Regions, Genetic|*Zinc Finger Motifs|Exons|Base Sequence|Introns|DNA-Binding Proteins|TATA Box|Transcription Factors|Response Elements|Amino Acid Sequence|Genes, Reporter|RNA, Messenger|Cloning, Molecular|Sequence Deletion|*Genomics|Cell Line 17 CAMK2N2 10811820 J. Cell Biol. 2000 PMC2174561 10.1083/jcb.149.4.783 19 32 0 46 *Calmodulin|*Synaptic Transmission|*Neurotrophin 3|Neuromuscular Junction|Receptor, IP3|BDNF protein, human|Brain-Derived Neurotrophic Factor|Ryanodine Receptors|CaM KII|NTF3 protein, human|Calcium|Signal Transduction|*Cytoplasm|Neurotransmitter Agents 17 GNB1L 11072084 Biochim. Biophys. Acta 2000 10.1016/s0167-4781(00)00189-5 7 0 0 56 Humans|*DiGeorge Syndrome|*G-Protein beta Subunit|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Marfan Syndrome|Exons|*Craniosynostoses|Amino Acid Sequence|Base Sequence|cDNA|Chromosome Mapping|Introns|Cloning, Molecular|Blotting, Northern|*Peptides|PCR|Chromosome Deletion|cDNA Library 17 NAGPA 21214445 Pharm Biol 2000 10.1076/1388-0209(200004)3821-1FT081 0 0 0 19 Animals|Rabbits|*Blood Glucose|Tanzania|Oral Glucose Tolerance Test|Caesalpinia|*Seeds|Hypoglycemic Agents|Fasting|Diabetes Mellitus, Experimental|Plant Extracts|Glucose 17 RAB6C 11054569 Gene 2000 10.1016/s0378-1119(00)00395-4 15 1 2 56 Humans|Female|Drug Resistance, Multiple|*MCF7 Cells|Doxorubicin|Drug Resistance, Neoplasm|Cell Line, Tumor|DNA Methylation|Sarcoma|Transfections|Vinblastine|Taxol|Gene Expression Regulation, Neoplastic|Uterine Neoplasms 17 RAPGEF5 10934204 J. Biol. Chem. 2000 10.1074/jbc.M005327200 39 13 1 1596 Animals|Chlorocebus aethiops|*Guanine Nucleotide Exchange Factors|RAP1A protein, human|rap1 GTP-Binding Proteins|ras GEFs|Generalized Epilepsy with Febrile Seizures Plus|*Seizures, Febrile|ras Proteins|*Epilepsy, Generalized|COS Cells|Protein Binding|Transfection|Enzyme Activation|Mitogen-Activated Protein Kinases|Guanosine Triphosphate 17 RAB6C 10455022 Biochem. J. 1999 PMC1220472 19 9 0 56 Humans|*Thrombin|*Protein Kinase C|*Phosphorylation|*Blood Platelets|Platelet Activation|GTP Binding Protein|Exocytosis|Cell Membrane|Amino Acid Sequence|Membrane Proteins|*Signal Transduction|*Blood Coagulation|Cytosol|Calcium|Guanosine Triphosphate 17 ZNF146 10600030 Hybridoma 1999 10.1089/hyb.1999.18.431 0 0 0 42 Humans|Cattle|Animals|Mice|*Zinc Finger|ZNF146 protein, human|*RNA-Binding Proteins|*Kruppel-Like Transcription Factors|Western Immunoblotting|*Pancreatic Neoplasms|Amino Acid Sequence|Immunofluorescence|Antibodies, Monoclonal 17 ZNF146 10449921 Cytogenet. Cell Genet. 1999 10.1159/000015316 1 0 0 42 Humans|Cattle|Animals|Mice|Zinc Fingers|Sequences, Amino Acid|Transcription Factors|Kruppel-Like Transcription Factors|RNA-Binding Proteins|Cloning, Molecular|*Pancreatic Cancer|Chromosome Mapping|cDNA|Chromosome Banding|mRNA|Gene Expression|In Situ Hybridization, Fluorescence|Sequence Homology, Amino Acid|*Chromosome 17 ZNF146 9935176 Int. J. Cancer 1999 10.1002/(sici)1097-0215(19990129)80:3<369::aid-ijc6>3.0.co;2-y 1 0 0 42 Humans|*Zinc Finger|RNA-Binding Proteins|Kruppel-Like Transcription Factors|*Pancreatic Neoplasms|Amino Acid Sequence|Gene Amplification|Cell Lines 17 CAMK2N2 9724800 Proc. Natl. Acad. Sci. U.S.A. 1998 PMC27991 10.1073/pnas.95.18.10890 110 0 2 46 Animals|Rats|Humans|*Calmodulin|HEK293 Cells|Phosphorylation|Calmodulin-Dependent Protein Kinase II|*Protein Kinase Inhibitors|CaM-KK|Amino Acid Sequence|CAMK1 protein, human|Calcium-Calmodulin-Dependent Protein Kinase Type 1|Protein Kinase|Kinetics|cDNA Library|Cloning, Molecular|*Brain|Catalytic Domain 17 rnf113a 9224902 Gene 1997 10.1016/s0378-1119(97)00108-x 1 0 0 51 Humans|Cattle|Animals|*RING Finger Domains|Zinc Fingers|DNA-Binding Proteins|Transcription Factors|Base Sequence|Chromosome Mapping|Amino Acid Sequence|Gene Expression|Cloning, Molecular|Sequence Alignment|Repressor Proteins|DNA, Complementary|Sequence Homology, Amino Acid|RNA, Messenger|*Chromosome Structures 17 ZNF146 8665923 Eur. J. Biochem. 1996 10.1111/j.1432-1033.1996.00991.x 1 1 0 42 Humans|*Zinc Finger Motifs|*Cell Nucleus|RNA-Binding Proteins|Kruppel-Like Transcription Factors|Amino Acid Sequence|Nuclear Protein|Trans-Activators|Blotting, Western|Cell Line|DNA|Zinc 17 ZNF146 8641144 Cytogenet. 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Biol. 1994 10.1006/jmbi.1994.1151 1 0 0 42 Humans|*Zinc Finger|Transcription Factors|cDNA|Base Sequence|Amino Acid Sequence|Kruppel-Like Transcription Factors|mRNA|Chromosome Mapping|Repressor Proteins|Blotting, Northern|Cloning, Molecular|Gene Expression|Sequence Homology, Amino Acid|Cell Line|Open Reading Frame 17 ARL4D 31959204 Clin Epigenetics 2020 PMC6972030 10.1186/s13148-020-0807-x 0 0 0 72 Humans|*DNA Methylation|*Stomach Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Gene Expression Profiling|Biomarkers, Tumor|*Nucleotide Motifs|Neoplasm Staging|Neoplasm Recurrence, Local|Disease Progression 16 ARL4D 31932503 J. Cell. 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Genomics 2020 10.1007/s00438-020-01649-x 0 0 0 123 Humans|*Human Papilloma Virus|*Papillomavirus Infections|Neoplasm Recurrence, Local|*Laryngeal Neoplasms|*Papilloma|Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Apoptosis|Cell Line, Tumor|Up-Regulation|Downregulation|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins|MIRN1224 microRNA, human 16 ogfod1 31927932 J. 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Genomics 2019 PMC6345039 10.1186/s40246-018-0189-8 0 1 0 64 Humans|*Endothelial Cells|*Myocardial Infarction|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Gene Frequency|Coronary Artery Disease|Genotype|Case-Control Studies|Risk Factors|Platelet Endothelial Cell Adhesion Molecule 1|*Smooth Muscle Cells 17 LINC00707 31788103 Oncol Lett 2019 PMC6865129 10.3892/ol.2019.10959 0 7 0 0 *Carcinoma, Non-Small-Cell Lung|*Cisplatin|*Lung Neoplasms|*Long Non-Coding RNA|Drug Resistance, Neoplasm|A549 Cells|Cell Proliferation|MicroRNAs|Antineoplastic Agents|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|Signal Transduction 16 LINC00707 31272297 Biosci. Biotechnol. Biochem. 2019 10.1080/09168451.2019.1637245 1 2 0 0 Rats|Animals|*Lipopolysaccharides|*PC12 Cells|*Apoptosis|RNA, Long Noncoding|*Inflammation|NeuroD protein|*Basic Helix-Loop-Helix Transcription Factors|*Nerve Tissue Proteins|MicroRNAs|Up-Regulation|Injury, Spinal Cord 16 LINC00707 31239777 Cancer Manag Res 2019 PMC6559252 10.2147/CMAR.S210845 3 1 0 0 16 LINC00707 31213848 Onco Targets Ther 2019 PMC6549427 10.2147/OTT.S198140 3 0 0 0 16 LINC00707 31115001 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201905_17801 2 7 0 0 *Colorectal Cancer|*Cell Proliferation|Long Non-Coding RNA|MicroRNAs|Neoplasm Invasiveness|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Colonic Neoplasms 16 LINC00707 30795799 Stem Cell Res Ther 2019 PMC6387535 10.1186/s13287-019-1161-9 10 19 0 0 Humans|*Osteogenesis|*RNA, Long Noncoding|*Mesenchymal Stem Cells|*Bone Marrow|Cell Differentiation|Osteoblasts|Bone Marrow Cells|WNT2B protein, human|*Wnt Proteins|MicroRNAs|*Glycoproteins|*Upregulation|*Transcriptional Activation|Cells, Cultured|MIRN370 microRNA, human 16 LRCH1 31842790 BMC Med. Genet. 2019 PMC6916040 10.1186/s12881-019-0931-7 0 0 0 44 *Carbon Monoxide Poisoning|*Genome-Wide Association Study|Genetic Susceptibility|Polymorphism, Single Nucleotide|Case-Control Studies|calponin|Microfilament Proteins|Brain Diseases|Calcium-Binding Proteins 16 LRCH1 31392102 PeerJ 2019 PMC6673425 10.7717/peerj.7435 0 0 0 44 *Transcriptome|*Gene Expression Profiling|Genome-Wide Association Study|*Stroke|*Microarray Analysis|Gene Ontology|Quantitative Trait Loci|Genetic Predisposition to Disease|Phenotype 16 LRP3 31426957 Carbohydr Polym 2019 10.1016/j.carbpol.2019.115104 0 0 0 44 *Lycium|*Pectins|Polysaccharides|Fruits|Molecular Weight|Rhamnose|Galactose|Arabinose|Hydrolysis|*Epithelial Cells|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|*Adenocarcinoma 16 LRP3 30669037 J. Hazard. Mater. 2019 10.1016/j.jhazmat.2019.01.029 0 4 0 44 *Rahnella|*Copper|*Phosphate|Soil|Soil Pollutants|Bioremediation|Soil Microbiology|Heavy Metals|Mining|Bacteria|Biomineralization|Spectrometry, X-Ray Emission 16 LRRC10 31270560 Mamm. Genome 2019 PMC6836689 10.1007/s00335-019-09809-0 1 0 0 52 Humans|Mice|Animals|Child|*Precision Medicine|*Genome|Genomics|Computational Biology|Phenotype|Genome-Wide Association Study|Proteins|Drug Discovery|LRRC10 protein, human|Microfilament Proteins 16 mex3b 31493864 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.08.158 0 0 0 72 Mice|Animals|Asthma|*Inflammation|Neutrophils|Th2 Cells|Mice, Inbred BALB C|*Steroids|*RNA Binding Protein|Lung|Neutrophil Infiltration|Disease Models, Animal 16 mex3b 31330219 J. Allergy Clin. Immunol. 2019 10.1016/j.jaci.2019.07.009 1 4 0 72 Humans|*Nasal Polyps|TLR3 protein, human|*Toll-Like Receptor 3|*Sinusitis|Rhinitis|*Cells, Epithelial|Nasal Mucosa|Cytokines|Cells, Cultured|*Chronic Disease|MEX3B protein, human|RNA-Binding Proteins 16 MLIP 31072939 N C Med J 2019 10.18043/ncm.80.3.135 1 0 0 72 16 NOC3L 31383772 Gut 2019 10.1136/gutjnl-2019-318760 0 4 0 95 Humans|*Genome-Wide Association Study|*Stomach Neoplasms|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Case-Control Studies|Genetic Loci 16 NOC3L 30741601 Cell Cycle 2019 PMC6464578 10.1080/15384101.2019.1578522 0 3 0 95 Humans|Replication Origins|Origin Recognition Complex|DNA Replication|Minichromosome Maintenance Proteins|Cell Cycle Proteins|Chromatin|Cell Cycle|Budding Yeast 16 ogfod1 31112528 JCI Insight 2019 PMC6629114 10.1172/jci.insight.128496 1 7 0 123 Humans|*Prolyl Hydroxylase|*Ribosomes|*Procollagen-Proline Dioxygenase|*RNA Splicing|Protein Biosynthesis|Hydroxylation|Protein Processing, Post-Translational|*Cell Differentiation|Nuclear Proteins|Carrier Proteins|mRNA|2-Oxoglutarate|Gene Knockdown Techniques|TTN protein, human|Titin|*Organogenesis|Cardiomyocytes|OGFOD1 protein, human 16 PHACTR4 31386143 Genome Biol Evol 2019 PMC6735850 10.1093/gbe/evz111 0 0 0 152 Animals|*Genome|Tyto alba|*Genomics|Scotopic Vision|*Phenotype|*Adaptation, Physiological|Photopic Vision|Phylogenomics|Scotopic Adaptation|Retina|*Acclimatization 16 PHF23 31748606 Sci Rep 2019 PMC6868234 10.1038/s41598-019-53610-7 0 0 0 40 Mice|Animals|*Mice, Transgenic|nuclear pore complex protein 98|Nuclear Pore Complex Proteins|*Transcription Factors|*Leukemia, Myeloid, Acute|*Precursor B-Cells|Homeodomain Proteins|Oncogene Proteins, Fusion|Myelodysplastic Syndromes|Thymocytes|Cell Transformation, Neoplastic|Hoxd13 protein, mouse 16 PHF23 31592908 Chin. Med. J. 2019 PMC6846253 10.1097/CM9.0000000000000402 0 5 0 40 *Chondrocytes|*Osteoarthritis|*Autophagy|Articular Cartilage|*Apoptosis|*Homeodomain Proteins|Interleukin-1beta|Transcription Factors 16 PHF23 30992267 Blood 2019 PMC6566592 10.1182/blood.2018864173 1 1 0 40 *B-Lymphocyte Subsets|*Precursor Cells, B-Lymphoid|*Transcription Factors|*Leukemia, Myeloid, Acute|*Mutations|Homeodomain Proteins|Oncogene Proteins, Fusion|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 16 PKD1L2 31493508 Gene 2019 10.1016/j.gene.2019.144100 0 0 0 9 Humans|Female|*mRNA|*Prognosis|RNA, Neoplasm|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate 16 PKD1L2 30659259 Eur. J. Hum. Genet. 2019 PMC6460579 10.1038/s41431-018-0296-y 2 0 0 9 Humans|*Genome-Wide Association Study|Japan|*Amino Acids|Biomarkers|Serine|Case-Control Studies|Glycine|*Genetic Testing 16 RCBTB1 31494449 Stem Cell Res 2019 10.1016/j.scr.2019.101549 0 0 0 75 Humans|Female|Middle Aged|*Induced Pluripotent Stem Cells|Cellular Reprogramming|Octamer Transcription Factor-3|SOXB1 Transcription Factors|Kruppel-Like Transcription Factors|Cell Differentiation|Fibroblasts|Proto-Oncogene Proteins c-myc|*Mutations|Cells, Cultured|Genetic Vectors|*Retinal Dystrophies|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors 16 RCBTB1 30641971 Cancers (Basel) 2019 PMC6356223 10.3390/cancers11010081 1 19 0 75 *Docetaxel|*Soft Tissue Sarcomas|*Soft Tissue Neoplasms|Taxoids|Deoxycytidine|Disease-Free Survival|Antineoplastic Combined Chemotherapy Protocols 16 SCAPER 31437301 J. Cutan. Pathol. 2019 10.1111/cup.13566 1 0 0 22 Adult|Female|Animals|Child|Humans|*DNA Copy Number Variations|Neoplasm Recurrence, Local|Blue Nevi|Melanoma|Nevus, Spitz|Skin Neoplasms|Carney Complex|Scalp|Mutation|Lymph Node|Diagnosis, Differential|Nevi, Dysplastic|Gene Fusion 17 SCAPER 31069901 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61172 0 0 0 22 Adult|Humans|Mice|Animals|*Homozygote|*Intellectual Disability|Sequence Deletion|Retinitis Pigmentosa|Genes, Recessive|Pedigree|Eye Proteins|Stop Codon, Premature|Exons|*Syndromes|Mutation|Carrier Proteins 17 SCAPER 30723319 Eur. J. Hum. Genet. 2019 PMC6777442 10.1038/s41431-019-0347-z 3 0 0 22 Humans|Mice|Animals|*Bardet-Biedl Syndrome|*Cilia|Retinitis Pigmentosa|*Mutation|Proteins|Carrier Proteins|Intellectual Disability|Whole Exome Sequencing|Tubulin|Genetic Linkage 17 SELENON 31880214 Ren Fail 2019 PMC6735353 10.1080/0886022X.2019.1641413 0 0 0 179 Humans|*Mesangial Cells|*Endoplasmic Reticulum|FN1 protein, human|Fibronectin|*Transforming Growth Factor|Endoplasmic Reticulum Stress|Selenoproteins|Transforming Growth Factor beta1|Cells, Cultured|Glucose 19 SELENON 31874912 Dis Model Mech 2019 PMC6955215 10.1242/dmm.041368 2 0 0 179 Central Core Disease|Ryanodine Receptor 1|Myopathies, Structural, Congenital|Muscle, Skeletal|Mutations|Phenotype 19 SELENON 31321302 Neurol Genet 2019 PMC6563518 10.1212/NXG.0000000000000341 2 0 0 179 Adult|Humans|Myopathies, Structural, Congenital|Muscle, Skeletal|Mutation|Retrospective Studies 19 SELENON 30932294 Hum. Mutat. 2019 PMC6660981 10.1002/humu.23745 2 1 0 179 Humans|Minicore Myopathy with External Ophthalmoplegia|Myopathies, Structural, Congenital|Myopathy, Central Core|Ryanodine Receptor Calcium Release Channel|Muscle, Skeletal|Malignant Hyperthermia|Muscle Weakness|Ophthalmoplegia|Epigenesis, Genetic|Mutation|*Epigenetic|DNA Methylation|Selenoproteins 19 SELENON 30921636 Redox Biol 2019 PMC6438913 10.1016/j.redox.2019.101176 2 2 0 179 Humans|Mice|Animals|*Insulin Resistance|*Muscle, Skeletal|*Endoplasmic Reticulum Stress|Myotubes|Insulin|*Saturated Fatty Acids|Endoplasmic Reticulum|Myopathy|Diet, High-Fat|Palmitates|Dietary Fat|Glucose Intolerance|*Protective Agents|Signal Transduction|SEPN1 protein, human|Muscle Proteins|Selenoproteins|SEPN1 protein, mouse 19 STXBP5L 30851173 J Gastrointestin Liver Dis 2019 10.15403/jgld.2014.1121.281.crr 0 0 0 36 Humans|*Liver Transplantation|*Liver Cirrhosis|Hepatitis C|*Disease Progression|Donor|Risk Factors|Recurrence|Cohort Studies|Severity of Illness Index|Risk Assessment|Time Factors 16 STXBP5L 30819905 Haematologica 2019 PMC6886420 10.3324/haematol.2018.204990 0 0 0 36 Humans|*Whole Exome Sequencing|Pilot Projects|Blood Platelet Disorders|Exome|Sequence Analysis, DNA|Genetic Predisposition to Disease|Pedigree|Platelet|Phenotype|Hemorrhagic Disorders|Genetic Association Studies 16 TBC1D23 31624125 Proc. 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Cancer 2019 10.1002/ijc.32619 0 0 0 84 Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Germ-Line Mutation|*Genes, BRCA2|BRCA2 protein, human|*BRCA2 Protein|*Chinese|Carcinoma, Squamous Cell|Genetic Predisposition to Disease|*Loss of Function Mutation|China|Hongkong 16 TTC39B 30662451 Front Genet 2019 PMC6329279 10.3389/fgene.2018.00682 1 0 0 84 *Cancer|CD274 protein, human|B7-H1 Antigen|*Oncogenes|Immunotherapy|CTLA4 protein, human|CTLA-4 Antigen|Data Mining|Databases, Genetic|*Gene Expression 16 UBR3 30896406 Elife 2019 PMC6428570 10.7554/eLife.39748 0 12 0 148 Animals|Drosophila Proteins|Transcription Factors|DNA-Binding Proteins|Drosophila|Gene Expression Regulation, Developmental|Transcription, Genetic|Epidermal Cells|Epidermis|Signal Transduction|Open Reading Frames 16 UNCX 31360146 Clin Proteomics 2019 PMC6637644 10.1186/s12014-019-9249-x 1 0 0 15 *Proteomics|*Bone Marrow Stromal Cells|*Bone Marrow|*Co-culture|Isotope Labeling|Cell Communication|Cell Line|*Protein Processing, Post-Translational|Proteins|Hematopoietic Stem Cell Transplantation 16 UNCX 31193955 Gene X 2019 PMC6543554 10.1016/j.gene.2019.100011 1 0 0 15 Animals|Zebrafish|Zebrafish Proteins|Body Patterning|Gene Expression Regulation, Developmental|Transcription Factor|Hedgehog Proteins|DNA-Binding Proteins|Embryogenesis|Mesoderm|Trans-Activators|In Situ Hybridization|Signal Transduction|Mutation 16 VPS13D 31876103 Mol Genet Genomic Med 2019 PMC7057107 10.1002/mgg3.1108 1 0 0 60 Humans|Child|*Spastic Paraplegia, Hereditary|Spastic Ataxia|Optic Atrophy|Spinocerebellar Ataxias|Cohen syndrome|Intellectual Disability|Mutations|Heterozygote|Muscle Spasticity|Phenotypes|Pedigree|Parkinsonism|Developmental Disabilities|Fingers|Microcephaly|Muscle Hypotonia|Myopia|Obesity 18 VPS13D 31277379 Int J Mol Sci 2019 PMC6651490 10.3390/ijms20133284 1 3 0 60 Animals|Mice|microtubule-associated protein 1B|*Microtubule-Associated Proteins|alpha Synuclein|*Synapse|Parkinson Disease|*Brain|Protein Kinases|*Autophagy|Phosphorylation|Disease Models, Animal 18 VPS13D 31270560 Mamm. Genome 2019 PMC6836689 10.1007/s00335-019-09809-0 1 0 0 60 Humans|Mice|Animals|Child|*Precision Medicine|*Genome|Genomics|Computational Biology|Phenotype|Genome-Wide Association Study|Proteins|Drug Discovery|LRRC10 protein, human|Microfilament Proteins 18 ARL4D 30382149 Sci Rep 2018 PMC6208435 10.1038/s41598-018-34522-4 3 1 0 72 *Interleukin-2|*GTPase|CD8-Positive T-Lymphocytes|CD274 protein, human|B7-H1 Antigen|Programmed Cell Death 1 Receptor|Endothelial Cell|Signal Transduction|Liver 16 ARL4D 30191368 Breast Cancer Res. Treat. 2018 10.1007/s10549-018-4957-x 0 0 0 72 Humans|Female|*Hereditary Breast and Ovarian Cancer Syndrome|BRCA1 protein, human|*BRCA1 Protein|Genes, BRCA1|*Exons|Genes, BRCA2|Germ-Line Mutation|Ovarian Neoplasms|Chromosome Breakpoints|Comparative Genomic Hybridization|Pedigree|Genetic Predisposition to Disease|Gene Rearrangement|DHX8 protein, human|RNA Splicing Factors|DEAD-box RNA Helicases 16 ATXN8 29517052 Neurol Clin Pract 2018 PMC5839675 10.1212/CPJ.0000000000000421 5 0 0 7 Humans|*Neurologists|*Ataxia, Hereditary|*Genetic Testing|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Phenotypes 18 cdkl1 29420175 Cell Rep 2018 PMC5846859 10.1016/j.celrep.2017.12.083 11 6 0 103 Animals|Humans|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Cilia|Cyclin-Dependent Kinases|Mitogen-Activated Protein Kinases|Signal Transduction|Sensory Receptor Cells|Mutations|CDKL-1 protein, C elegans 16 EFHD1 30060475 Int J Mol Sci 2018 PMC6121686 10.3390/ijms19082192 3 40 0 78 *Energy Metabolism|Oxidative Phosphorylation|Glycolysis|Receptors, Antigen, B-Cell|Mitochondria|Progenitor B-Cells|B Cells|Adenosine Triphosphate|Signal Transduction|Antigen Receptor|Lymphocyte Activation 16 EPPK1 29993813 IEEE/ACM Trans Comput Biol Bioinform 2018 10.1109/TCBB.2018.2813375 0 0 0 76 Cancer|*Oncogenes|*Mutation|Computational Biology|Mutation Frequency|Neoplasm Proteins|Algorithm|Genes, p16 16 EPPK1 29950347 Mol. Cell Proteomics 2018 PMC6126387 10.1074/mcp.RA118.000562 8 0 0 76 Humans|*Proteomics|*Urinary Bladder|*Urinary Bladder Neoplasms|Urothelium|*Carcinoma, Transitional Cell|Biomarkers, Tumor|Chromatography, Liquid|Tandem Mass Spectrometry|Gene Expression Profiling|*Cytodiagnosis|Cell Differentiation|AHNAK protein, human|Membrane Proteins|Neoplasm Proteins 16 FOXS1 30500980 J. Cell. Biochem. 2018 10.1002/jcb.26821 1 3 0 119 Humans|*Epithelial-Mesenchymal Transition|*Stomach Neoplasms|*Wnt Pathway|*Downregulation|beta Catenin|Gene Expression Regulation, Neoplastic|*Catenins|Cell Movement|*Neoplastic Processes|Cell Proliferation|MicroRNAs|Cell Line, Tumor|Tumorigenesis|Apoptosis 16 FOXS1 30098229 Mol Oncol 2018 PMC6166001 10.1002/1878-0261.12366 2 32 0 119 Humans|GLI1 protein, human|*Zinc Finger Protein GLI1|Hedgehog Proteins|Medulloblastoma|Patched Receptors|Cerebellar Neoplasms|Patched-1 Receptor|Signal Transduction|Transcription Factor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Rhabdomyosarcoma|Cell Line, Tumor|RNA, Small Interfering 16 Gon4l 29683819 Am. J. Surg. Pathol. 2018 PMC6041134 10.1097/PAS.0000000000001070 12 0 0 45 Adult|Humans|Male|Female|tropomyosin-related kinase-B, human|Receptor, trkB|Melanoma, Cutaneous Malignant|*Melanoma|Receptor, trkC|Receptor, trkA|ALK protein, human|Anaplastic Lymphoma Kinase|Skin Neoplasms|Gene Fusion|Immunohistochemistry|Membrane Glycoproteins|Biomarkers, Tumor|Sequencing, Next-Generation|In Situ Hybridization, Fluorescence|Translocation, Genetic|GON4L protein, human|Transcription Factors 16 Gon4l 29615614 Nat Commun 2018 PMC5882663 10.1038/s41467-018-03715-w 4 1 0 45 Animals|*Cell Polarity|*Notochord|Zebrafish|*Embryonic Development|Gastrulation|Zebrafish Proteins|Embryo, Nonmammalian|Body Patterning|Gene Expression Regulation, Developmental|Signal Transduction|Cell Movement|*Organogenesis|Morphogenesis|Udu protein, zebrafish 16 grwd1 29991511 J. Cell. Sci. 2018 10.1242/jcs.213009 1 12 0 169 *Proteasome Endopeptidase Complex|*Ubiquitin|TP53 protein, human|Tumor Suppressor Protein p53|Proto-Oncogene Proteins c-mdm2|benzyloxycarbonylleucyl-leucyl-leucine aldehyde|Leupeptins|Binding Protein|E3 Ubiquitin Ligase|Ubiquitylation|Histone|Proteolysis|Cell Cycle Proteins|DNA Replication|Proteasome Inhibitor|Protein Binding|Transcriptional Activation|Cell Nucleolus 16 grwd1 29976152 BMC Neurosci 2018 PMC6034256 10.1186/s12868-018-0438-8 1 4 0 169 Humans|Mice|Animals|*Encephalitis Viruses, Tick-Borne|*Chromosomes, Human, Pair 7|*BALB C Mice|Encephalitis, Tick-Borne|Chromosome Mapping|IL10 protein, human|IL10|DC-specific ICAM-3 grabbing nonintegrin|Lectins, C-Type|Disease Susceptibility|CCR5 protein, human|Receptors, CCR5|Receptors, Cell Surface|Cell Adhesion Molecules|Oas1b protein, mouse|2',5'-Oligoadenylate Synthetase 16 grwd1 29518789 Cell. Physiol. Biochem. 2018 10.1159/000487976 1 0 0 169 Humans|*DNA Methylation|*B-DNA|Epigenesis, Genetic|CpG Islands|Epigenetics|Genome, Human|Oligonucleotide Array Sequence Analysis|Genomics|Metabolic Diseases|Leukocytes, Mononuclear|Traditional Chinese Medicine 16 grwd1 29357053 Adv. Exp. Med. Biol. 2018 10.1007/978-981-10-6955-0_3 3 1 0 169 Humans|Animals|*Chromatin|Replication Origins|MCM2-7 Complex|SMARCA5 protein, human|Cell Cycle Proteins|Nucleosomes|DNA Replication|Chromatin Assembly and Disassembly|Histones|Adenosine Triphosphatases|G1 Phase|Acetylation|Protein Binding|GRWD1 protein, human|Carrier Proteins 16 grwd1 29353130 Eur. J. Obstet. Gynecol. Reprod. Biol. 2018 10.1016/j.ejogrb.2018.01.006 1 9 0 169 Humans|Female|*miRNA|*Data Analysis|*Pilot Projects|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Gene Expression Regulation, Neoplastic|*Microarray Analysis|Gene Regulatory Networks|Gene Expression Profiling|Down-Regulation|Computational Biology|Biomarkers, Tumor|MIRN-1181 microRNA, human 16 KIAA1279 30012197 Biol. 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Biochem. 2018 10.1159/000487693 11 2 0 0 Humans|*RNA, Long Noncoding|*Lung Adenocarcinoma|*Cell Proliferation|Lung Cancer|Adenocarcinoma|Cell Movement|Cell Line, Tumor|Neoplasm Staging|Gene Expression Regulation, Neoplastic|RNA Interference|RNA, Small Interfering|Apoptosis|Up-Regulation 16 LINC00707 29436619 Int. J. Oncol. 2018 PMC5843393 10.3892/ijo.2018.4268 11 2 0 0 Humans|*RNA, Long Noncoding|*Prognosis|*Melanoma|Kaplan-Meier Analysis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Transcriptome|Cluster Analysis|ROC Curve|Area Under Curve|mRNA 16 LRCH1 29936662 J. Mol. 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Cancer Res. 2018 PMC6050090 10.1158/1078-0432.CCR-18-0698 1 0 0 72 *Antigen Presentation|*Immunotherapy|HLA-A Antigens|T-Lymphocytes, Cytotoxic|Antigens, Neoplasm|*Immunologic Factors 16 mex3b 29515040 JCI Insight 2018 PMC5922278 10.1172/jci.insight.98212 1 0 0 72 Child|Infant|Child, Preschool|Humans|*Diabetes Mellitus, Type 1|*Transcriptome|*Autoantibodies|Islets of Langerhans|Glutamate Decarboxylase|Autoimmunity|Insulin|Genetic Susceptibility|Seroconversion|Genotype|Disease Progression|ZNF714 protein, human|DNA-Binding Proteins|Transcription Factors 16 mex3b 29496759 Clin. Cancer Res. 2018 10.1158/1078-0432.CCR-17-2483 8 2 0 72 16 mex3b 29417297 Gastric Cancer 2018 10.1007/s10120-018-0801-6 4 10 0 72 *Stomach Neoplasms|Runx3 protein, human|Core Binding Factor Alpha 3 Subunit|Long Non-Coding RNA|Gene Expression Regulation, Neoplastic|MicroRNAs|*Stomach|Cell Proliferation|Cell Movement|Cell Line, Tumor|*Ubiquitination|*Neoplastic Processes 16 MLIP 30389785 J. Biol. Chem. 2018 PMC6314141 10.1074/jbc.RA118.003758 0 0 0 72 Mice|Animals|*Transcription Initiation Site|Alternative Splicing|Exons|*Lamins|Protein Isoforms|*Muscle|Carrier Proteins|Nuclear Proteins|Amino Acid Sequence|RNA, Messenger|MLIP protein, mouse 16 MLIP 29935515 J Chem Phys 2018 10.1063/1.5027283 0 0 0 72 *Machine Learning|Artificial Intelligence|Algorithms|Metals|Transition Elements 16 ogfod1 30427558 Chemistry 2018 PMC6471485 10.1002/chem.201804790 1 0 0 123 Humans|*Prolyl Hydroxylase|*Procollagen-Proline Dioxygenase|Prolyl-Hydroxylase Inhibitors|*Ribosomes|Ribosomal Proteins|Transcription Factors|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins 16 ogfod1 30254109 Genes Dev. 2018 PMC6169836 10.1101/gad.313007.118 3 4 0 123 AHR protein, human|*Receptors, Aryl Hydrocarbon|*Basic Helix-Loop-Helix Transcription Factors|*Cell Nucleolus|Proto-Oncogene Proteins c-myc|Ribosomes|Transcription, Genetic|Tumors|Gene Expression Regulation|Cell Proliferation 16 PHACTR4 29691780 Dig. Dis. Sci. 2018 10.1007/s10620-018-5081-9 1 0 0 152 *Stomach Neoplasms|Adenosine Deaminase|Editing, RNA|Inosine|3' Untranslated Regions|*Gene Expression Regulation|RNA-Binding Proteins|MicroRNAs|RNA, Messenger|Adenosine 16 PHF23 29296821 Blood Adv 2018 PMC5728343 10.1182/bloodadvances.2017009837 6 0 0 40 Mice|Animals|*Critical Pathways|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Receptors, Cytokine|*Mutations|*Burkitt Lymphoma|B-Cell Leukemia|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Signal Transduction|B-Lymphocytes|Lymphocytes, B-2 16 PKD1L2 29703930 Sci Rep 2018 PMC5923232 10.1038/s41598-018-24967-y 5 2 0 9 Humans|*Whole Exome Sequencing|*Colon|Exomes|Mutations|Anorectal Anomalies|Open Reading Frames|Genes, Regulator|TSPAN32 protein, human|Tetraspanins 16 SCAPER 30561111 Am. J. Med. Genet. A 2018 PMC6349500 10.1002/ajmg.a.61001 1 0 0 22 Male|Humans|Child|*Retinitis Pigmentosa|Homozygote|Exome|Genes, Recessive|Pedigree|Eye Proteins|Mutation|Sequencing, Whole Exome 17 SELENON 30469315 Nutrients 2018 PMC6266908 10.3390/nu10111812 3 0 0 179 Humans|*Selenium|*Selenoprotein|Selenoprotein P|*Colorectal Cancer|Glutathione Peroxidase|*Adenoma|Polymorphism, Single Nucleotide|*Colonic Neoplasms|Cohort Studies|Nutritional Status|Ireland|Czech Republic 19 SELENON 30391828 Redox Biol 2018 PMC6223234 10.1016/j.redox.2018.10.017 4 2 0 179 Humans|Mice|Animals|*Endoplasmic Reticulum|SEPN1 protein, human|Selenoproteins|Muscle Proteins|Endoplasmic Reticulum Stress|Transcription Factor CHOP|Sarcoplasmic Reticulum Calcium-Transporting ATPases|Myopathies|Muscle, Skeletal|Knockout Mouse|Muscle Contraction|Signal Transduction|Apoptosis 19 SELENON 29709707 Free Radic. Biol. Med. 2018 10.1016/j.freeradbiomed.2018.04.572 6 0 0 179 Humans|*Selenoprotein|Selenocysteine|*Mutations|Selenium|Stop Codon|Protein Biosynthesis 19 SELENON 29673733 J Trace Elem Med Biol 2018 10.1016/j.jtemb.2018.03.003 1 0 0 179 Swine|Animals|*Sodium Selenite|*Selenium|*Selenite|*Dietary Sodium|Selenomethionine|glutathione peroxidase GPX1|Glutathione Peroxidase|*Diet|Dietary Supplement|Yeast, Dried|Animal Feed|Antioxidants|*Sodium Chloride, Dietary|Yeast|Muscle|Liver|Oxidative Stress 19 SH3BGRL3 30123134 Front Pharmacol 2018 PMC6085474 10.3389/fphar.2018.00861 2 4 0 83 *Stomach Neoplasms|ERBB2 protein, human|*Receptor, ErbB-2|Gene Amplification|Quinazolines|Cell Line, Tumor|herstatin|*Intercellular Signaling Peptides and Proteins 16 SH3BGRL3 29552294 Oncotarget 2018 PMC5844730 10.18632/oncotarget.23951 4 3 0 83 Humans|*Thyroid Cancer, Papillary|*Biopsy, Fine-Needle|*Proteome|*Transcriptome|Tandem Mass Spectrometry|Thyroid Neoplasms|Carcinoma, Papillary|Biomarkers, Tumor|Ultrasonography|ERAP2 protein, human|Aminopeptidases|GPNMB protein, human|Membrane Glycoproteins 16 SH3BGRL3 29547667 PLoS ONE 2018 PMC5856400 10.1371/journal.pone.0194591 3 2 0 83 *Sclerosis|Proteomics|*Pilot Projects|*Osteoblasts|*Bone|Osteoarthritis, Knee|Chondrocytes|Matrix Metalloproteinase 13|Cells, Cultured|Gene Expression 16 STXBP5L 29730043 Schizophr. 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Res. 2018 PMC6286207 10.1111/acer.13905 0 0 0 84 *Ethanol|*Epigenome|CpG Islands|DNA Methylation|*Brain|Alcohol Drinking|Genome-Wide Association Study|Biomarkers 16 TTC39B 31949581 Int J Clin Exp Pathol 2018 PMC6962934 1 0 0 84 Humans|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Genotype|Alleles|Coronary Disease|Asian Continental Ancestry Group|Stroke|Triglycerides|Risk Factors|Case-Control Studies|Lipids 16 TTC39B 29745376 Front Pharmacol 2018 PMC5938370 10.3389/fphar.2018.00459 0 0 0 84 Animals|Mice|*Mice, Knockout|epigallocatechin gallate|*Apolipoproteins E|*Atherosclerosis|*Catechin|*Liver|*Lipids|*Gene Expression|Inflammation|*Biochemical Phenomena|TTC39B protein, mouse|Lipoproteins, HDL 16 TTC39B 29593532 Front Pharmacol 2018 PMC5854642 10.3389/fphar.2018.00195 3 38 0 84 16 UBR3 30121816 J. Mol. Neurosci. 2018 10.1007/s12031-018-1134-y 3 0 0 148 Humans|*Intracranial Aneurysm|*Risk Factors|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Gene Frequency|Case-Control Studies|Genotype|Versicans|PRDM9 protein, human|Histone-Lysine N-Methyltransferase 16 VPS13D 29604224 Ann. Neurol. 2018 PMC6105379 10.1002/ana.25220 18 0 0 60 Spastic Ataxia|*Muscle Spasticity|Optic Atrophy|Ataxia, Spinocerebellar|*Cerebellar Ataxia|Intellectual Disability|*Ataxia|*Mutations|Spastic Paraplegia, Hereditary|Pedigree|Phenotype|*Mitochondria 18 VPS13D 29518281 Ann. Neurol. 2018 10.1002/ana.25204 14 0 0 60 Spastic Ataxia|Optic Atrophy|Spinocerebellar Ataxias|Spastic|Intellectual Disability|*Mutations|Spastic Paraplegia, Hereditary|Cerebellar Ataxia|Pedigree|Phenotype|*Movement Disorders 18 VPS13D 29374445 Curr. Biol. 2018 10.1016/j.cub.2017.12.017 1 0 0 60 *Mitophagy|*Mitochondrial Dynamics|Mitochondria|Mitochondrial Proteins|Mitochondrial Size|Ubiquitin-Protein Ligases|Ubiquitin|Phosphorylation|Binding Protein|Apoptosis|Signal Transduction|Protein Binding|*Kinetics 18 VPS13D 29307555 Curr. Biol. 2018 PMC5787036 10.1016/j.cub.2017.11.064 17 10 0 60 18 ARL4D 29180230 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.11.020 16 0 0 72 *Glucocorticoids|Corticosterone|Receptors, Glucocorticoid|DUSP1 protein, human|Dual Specificity Phosphatase 1|Cortisol|CXXC5 protein, human|Carrier Proteins|Transcriptomes|Transcription Factors|Signal Transduction|Up-Regulation|*Nervous System Physiological Phenomena|mRNA|Brain 16 ARL4D 28349920 Sci Rep 2017 PMC5368636 10.1038/srep45101 10 24 0 72 Mice|Animals|*Hippocampus|Phosphorylation|Signal Transduction|MAP Kinase Signaling System|Extracellular Signal-Regulated MAP Kinases|Mitogen-Activated Protein Kinase Kinases|Transcription Factors|Neurons|Nerve Tissue Proteins|Synapse|Regulation, Gene Action|Rgs2 protein, mouse|RGS Proteins|Ppp1r15a protein, mouse|Protein Phosphatase 1 16 ATXN8 28229454 Acta Neurol. Scand. 2017 10.1111/ane.12744 1 0 0 7 Humans|Brazil|Spinocerebellar ataxia 8|*Ataxia, Hereditary|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Alleles|Microsatellite Marker|Pedigree|Nerve Tissue Proteins|Haplotype|RNA, Untranslated|RNA, Long Noncoding|Mutation 18 c10orf11 28976636 Pigment Cell Melanoma Res 2017 10.1111/pcmr.12651 4 0 0 1 Child|Adult|Humans|Prospective Studies|*Albinism|Albinism, Ocular|Albinism, Oculocutaneous|TYRP1 protein, human|Membrane Glycoproteins|Mutations|Phenotype|Oxidoreductases|Membrane Transport Proteins|Genotypes|Polymerase Chain Reaction|GPR143 protein, human|Eye Proteins 16 c10orf11 28507374 J Pak Med Assoc 2017 2 0 0 1 Humans|*Whole Exome Sequencing|Pakistan|*Albinism, Oculocutaneous|*Genetic Testing|Mutation|Pedigree|Phenotypes|Monophenol Monooxygenase|Base Sequence|Membrane Transport Proteins|TYRP1 protein, human|Membrane Glycoproteins 16 cdkl1 28352193 Onco Targets Ther 2017 PMC5360398 10.2147/OTT.S133014 3 16 0 103 *Colorectal Cancer|Cell Proliferation|Cell Line, Tumor|Cell Movement|Gastric Cancer|RNA Interference|Cyclin-Dependent Kinases|*Colonic Neoplasms|RNA, Small Interfering|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Melanoma|Protein-Serine-Threonine Kinases|Apoptosis|Transfection|RNA, Messenger 16 EFHD1 28524857 Cell Death Differ. 2017 PMC5520169 10.1038/cdd.2017.52 10 6 0 78 *Precursor Cells, B-Lymphoid|*Lymphocyte Activation|B-Lymphocytes|Receptors, Antigen, B-Cell|Bone Marrow Cells|Cell Differentiation|Calcium-Binding Proteins|Mitochondria|*Hematopoiesis|Cell Line 16 EPPK1 29085461 Oncol Lett 2017 PMC5649615 10.3892/ol.2017.6751 1 10 0 76 TP53 protein, human|*Tumor Suppressor Protein p53|*Up-Regulation|Genes, p53|Mutation|Carcinoma, Squamous Cell|*Transcriptional Activation 16 FOXS1 29088749 Oncotarget 2017 PMC5650304 10.18632/oncotarget.17764 16 3 0 119 Humans|*Prognosis|*Signature, Gene Expression|*Stomach Neoplasms|Likelihood Functions|Gene Expression Profiling|Kaplan-Meier Analysis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cluster Analysis 16 FOXS1 28825201 Genetica 2017 10.1007/s10709-017-9980-z 1 0 0 119 Cattle|Animals|*Gene Regulatory Networks|Transcription Factors|Gene Expression Profiling|Promoter Regions, Genetic|*Immune System|Signal Transduction|Algorithms 16 FOXS1 28374495 Asia Pac J Clin Oncol 2017 10.1111/ajco.12688 2 0 0 119 Humans|*Stomach Neoplasms|*Gastroscopy|*Computational Biology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Biomarkers, Tumor|Profile, Gene Expression|Real-Time Polymerase Chain Reaction 16 FOXS1 28199372 PLoS ONE 2017 PMC5310909 10.1371/journal.pone.0171858 2 52 0 119 Pregnancy|Female|Cattle|Animals|*Transcription Factor|trophoblastin|Pregnancy Proteins|*Endometrium|Interferon Type I|*Gene Expression Regulation|Embryo Implantation|Uterus|Cells, Epithelial|Signal Transduction|3'-(1-butylphosphoryl)adenosine|Cells, Cultured|Ruminants|Downregulation|*Complement Factor B 16 Gon4l 28697878 Vet. J. 2017 10.1016/j.tvjl.2017.05.014 0 0 0 45 Dogs|Animals|Horses|Cattle|Swine|*Livestock|Chickens|Homozygote|Mutation|Achondroplasia|Phenotype|Breeding|Cattle Diseases 16 Gon4l 28381640 J. Immunol. 2017 PMC5444326 10.4049/jimmunol.1602054 1 23 0 45 *Precursor Cells, B-Lymphoid|*Cell Division|Transcription Factors|DNA-Binding Proteins|B-Lymphocytes 16 grwd1 28722511 Cell Cycle 2017 PMC5553401 10.1080/15384101.2017.1338987 3 3 0 169 Humans|*Ribosomal Proteins|*Nucleolar Proteins|*Ribosomes|*Cell Nucleolus|Proto-Oncogene Proteins c-mdm2|*Cell Transformation, Neoplastic|Tumor Suppressor Protein p53|*Oncogenesis|Tumor Suppressor Proteins|RNA, Ribosomal|Signal Transduction|Ribosomal Protein Biosynthesis|Transcriptional Activation|Up-Regulation|Cell Line, Tumor|Cell Proliferation|GRWD1 protein, human|Carrier Proteins 16 grwd1 28104961 Bioinformation 2017 PMC5237648 10.6026/97320630012054 1 6 1 169 Humans|Protein Interaction Network|Protein Interaction Mapping|*Proteins|Computational Biology|WDR5 protein, human|Histone-Lysine N-Methyltransferase|GRWD1 protein, human|Carrier Proteins 16 HMGB4 28096358 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5293106 10.1073/pnas.1615327114 7 1 0 26 Humans|Male|Testicular Germ Cell Tumor|cisplatin-DNA adduct|*Cisplatin|*Platinum|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Antineoplastic Agents|*HMGB3 Protein|Drug Resistance, Neoplasm|Excision Repair|Apoptosis|*DNA|Cell Line, Tumor|DNA Adducts|Cell Proliferation 16 INIP 29153107 Vet. J. 2017 10.1016/j.tvjl.2017.10.008 1 0 0 79 Humans|Dogs|Animals|*Epilepsy|*Heart|Electrocardiography|Seizures|Electroencephalography|Heart Rate|Autonomic Nervous System|Phenobarbitone|Atrial Fibrillation|Dog Diseases 16 INIP 29150435 Biochem. 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Thromb. Vasc. Biol. 2017 10.1161/ATVBAHA.117.309721 7 0 0 64 Mice|Humans|Animals|*Coronary Artery Disease|Genome-Wide Association Study|Neovascularization, Physiologic|Human Umbilical Vein Endothelial Cells|Cell Movement|Neovascularization, Pathologic|Vascular Endothelial Growth Factor A|Cell Proliferation|Intercellular Junctions|Carcinoma, Lewis Lung|Signal Transduction|Mice, Knockout|RNA Interference|Cells, Cultured 17 LRP3 29124841 Environ. Microbiol. 2017 10.1111/1462-2920.13992 2 2 0 44 *Sinorhizobium meliloti|*Cysteine|*Symbiosis|Gene Expression Regulation, Bacterial|Medicago sativa|Nitrogen Fixation|Bacterial Proteins|*Oxidative Stress|Transcription Factors|Nitrogen 16 LRP3 28340487 Stem Cell Res 2017 10.1016/j.scr.2017.03.001 6 1 0 44 Humans|*Osteogenesis|*Mesenchymal Stem Cells|*Cell Differentiation|Adipogenesis|Osteoblasts|Adipocytes|RNA, Micro|Bone Marrow Cells|Core Binding Factor Alpha 1 Subunit|mRNA|Cells, Cultured|RNA Interference|Upregulation|RNA, Small Interfering|Gene Expression Profiling|LRP3 protein, human|LDL-Receptor Related Proteins 16 LRRC10 28284154 Aquat. Toxicol. 2017 10.1016/j.aquatox.2017.02.024 3 0 0 52 Animals|*Zebrafish|*Oestradiol|*Estrogen Receptor alpha|estrophilin|*Receptors, Estrogen|GPER1 protein, human|*Receptors, G-Protein-Coupled|*Estrogens|Zebrafish Proteins|Embryo, Nonmammalian|Embryonic Development|Signal Transduction|Oocytes|Gene Expression Regulation, Developmental|GPER protein, zebrafish 16 MLIP 28296976 PLoS ONE 2017 PMC5351854 10.1371/journal.pone.0172995 17 16 0 72 *Exome|*Cardiomyopathy, Dilated|Mutation, Missense|Pedigree|Heterozygote|Adaptor Proteins, Signal Transducing|Apoptosis Regulatory Proteins 16 NOC3L 28200018 Brief. Bioinformatics 2017 10.1093/bib/bbx002 1 0 0 95 *Genome-Wide Association Study|Quantitative Trait Loci|Chromosome Mapping|Quantitative Trait, Heritable|Genotype|Phenotype|Polymorphism, Single Nucleotide|Genomics|Models, Genetic|Computational Biology 16 ogfod1 28257692 Am. J. Hum. Genet. 2017 PMC5339345 10.1016/j.ajhg.2017.01.034 22 4 0 123 Child|Humans|Autism Spectrum Disorder|Microcephaly|Intellectual Disability|*Ribosomes|Developmental Disabilities|Exome|Mutation, Missense|mRNA Translation|Mutation|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins 16 PHF23 28055972 Oncotarget 2017 PMC5355080 10.18632/oncotarget.14402 3 21 0 40 Humans|*Transcriptome|*Transcriptome Analysis|*Genomics|*Genes, Homeobox|Receptors, Estrogen|Gene Expression Regulation, Neoplastic|*Genes, Plant|Cell Line, Tumor|Transcription Factors|Proteins, Homeo Domain|DNA Copy Number Variations|*Databases, Genetic|Mutations|Cell Proliferation 16 PKD1L2 28271061 Front Cell Dev Biol 2017 PMC5318412 10.3389/fcell.2017.00005 2 6 0 9 Humans|Animals|*Zebrafish|Polycystic Kidney, Autosomal Dominant|TRPP Cation Channels|Disease, Polycystic Kidney|Mutations|TYRP1 protein, human|Membrane Glycoproteins 16 SCAPER 28794130 J. Med. Genet. 2017 10.1136/jmedgenet-2017-104632 5 0 0 22 RHYNS syndrome|Retinitis Pigmentosa|*Mutations|Electroretinography|Retina|Pedigree|Eye Proteins|Tomography, Optical Coherence|Phenotype|Visual Acuity|Hypopituitarism 17 SELENON 28855418 J. Nutr. 2017 10.3945/jn.117.247775 6 4 0 179 19 SELENON 28506443 Cell Calcium 2017 PMC5671369 10.1016/j.ceca.2017.05.001 12 9 0 179 Humans|*Calcium Signaling|*Selenoproteins|*Endoplasmic Reticulum|*Homeostasis|Endoplasmic Reticulum Stress 19 SH3BGRL3 28404947 Oncotarget 2017 PMC5503550 10.18632/oncotarget.15870 3 10 0 83 Humans|*Lung Adenocarcinoma|Adenocarcinoma|Lung Neoplasms|Biomarkers, Tumor|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Proteomics|Proteome|Liquid Chromatography|Receiver Operating Characteristic|Lung|*Body Fluids|Peptides 16 STXBP5L 28746398 PLoS ONE 2017 PMC5529015 10.1371/journal.pone.0180912 3 11 0 36 Mice|Animals|*Secretory Vesicles|Synaptic Vesicle|SNAREs|SYT1 protein, human|Synaptotagmin I|*Neurons|R-SNARE Proteins|Presynaptic Terminals|Synapsins|Membrane Fusion|Exocytosis|Nerve Tissue Proteins|Hippocampus|Synapse|Axons|Protein Transport|Plasma Membrane|tomosyn protein, mouse 16 TBC1D23 29184172 Nat. Cell Biol. 2017 10.1038/ncb3649 0 0 0 56 Humans|*Golgi Apparatus|*Endosomes|trans-Golgi Network|Golgins|Protein Transport|Membrane Proteins|HeLa Cells 16 TBC1D23 29084197 Nat. Cell Biol. 2017 PMC5712222 10.1038/ncb3627 13 11 0 56 Golgi complex autoantigen, 97-kDa|*Golgi Matrix Proteins|*Golgi Apparatus|*Endosomes|trans-Golgi Network|Protein Transport|Autoantigens|GTPase-Activating Proteins|Membrane Proteins|rab GTP-Binding Proteins|Transport Vesicles|Protein Domains|Biological Transport|Protein Binding 16 TBC1D23 28823707 Am. J. Hum. Genet. 2017 PMC5590842 10.1016/j.ajhg.2017.07.010 15 0 0 56 Child|Humans|Female|Pregnancy|Pontocerebellar Hypoplasia|*Cerebellar Diseases|*Homozygote|Cerebellar Hypoplasia|Nervous System Malformations|Microcephaly|Cerebellum|Developmental Disabilities|Intellectual Disability|Pedigree|Mutation|GTPase-Activating Proteins|*Neurogenesis|Phenotype|Pons|Neurons 16 TBC1D23 28823706 Am. J. Hum. Genet. 2017 PMC5590949 10.1016/j.ajhg.2017.07.015 12 0 0 56 Humans|Animals|Pontocerebellar Hypoplasia|*Cerebellar Diseases|*Homozygote|Microcephaly|Cerebellum|*Mutations|Nervous System Malformations|Cerebellar Ataxia|Pons|Phenotype|Pedigree|Zebrafish 16 TBC1D23 28397838 Mol. Psychiatry 2017 10.1038/mp.2017.60 0 0 0 56 *Whole Exome Sequencing|*Intellectual Disability|*Exome|DNA Copy Number Variations|Iran|Homozygote|Genes, Recessive|Pedigree|Mutations|Family|Genetic Heterogeneity|Chromosome Mapping|Mutations, Missense 16 TTC39B 29103089 Curr Cardiol Rep 2017 10.1007/s11886-017-0940-0 16 0 0 84 Humans|Animals|*Cholesterol, HDL|*Coronary Heart Disease|Genome-Wide Association Study|Mendelian Randomization Analysis|Genetic Predisposition to Disease|*Lipid Metabolism|Polymorphism, Single Nucleotide|Phenotype|Risk Factors|Risk Assessment|Human Genetics 16 TTC39B 31966470 Int J Clin Exp Pathol 2017 PMC6965879 0 0 0 84 Genetic Association Studies|Genetic Predisposition to Disease|Brain Ischemia|Polymorphism, Single Nucleotide|Gene Frequency|Stroke|Genotype|Coronary Artery Disease|Risk Factors|Case-Control Studies|Lipids 16 UNCX 28855354 Clin. Cancer Res. 2017 10.1158/1078-0432.CCR-17-1222 31 1 0 15 16 UNCX 28411256 Haematologica 2017 PMC5566027 10.3324/haematol.2016.163022 2 3 0 15 *Ectopic Gene Expression|*Cell Differentiation|Gene Expression Regulation, Leukemic|*Myeloid Cells|Leukemia, Myeloid, Acute|Translocation, Genetic|Oncogene Proteins, Fusion|Homeodomain Proteins|Transcription Factors|MicroRNAs|Gene Expression Profiling|*Epigenetic|Cell Proliferation 16 VPS13D 28749478 Genet. Med. 2017 10.1038/gim.2017.111 11 0 0 60 18 ATXN8 30713928 Mov Disord Clin Pract 2016 PMC6353394 10.1002/mdc3.12312 2 0 0 7 *Huntington Disease|*Chorea|Phenotype|Syndromes 18 BCAS4 27506935 Oncotarget 2016 PMC5308635 10.18632/oncotarget.11064 4 3 0 111 Humans|*Research Design|*Oncogene Fusion|Sequencing, Next-Generation|Gene Fusions|Sequence Analysis, RNA|Gene Expression Profiling|Sequence Analysis, DNA|DNA Copy Number Variations|*Phenotype|Cell Line, Tumor|Oncogene Proteins, Fusion|ZNF217 protein, human|Trans-Activators 16 BCAS4 27010659 Forensic Sci Int Genet 2016 10.1016/j.fsigen.2016.01.017 2 0 1 111 Humans|*Semen|*Saliva|*DNA Methylation|*Epigenetic|*Markers, DNA|CpG Islands|*Body Fluids|Forensic Genetics|hydrogen sulfite|Sulfites|*Bodily Secretions|Sequence Analysis, DNA|DNA|Epigenesis, Genetic 16 c10orf11 27564456 Epigenetics 2016 PMC5094634 10.1080/15592294.2016.1226451 19 4 0 1 Humans|Genome-Wide Association Study|*DNA Methylation|*Chronic Obstructive Pulmonary Disease|*Lung|Smoking|Quantitative Trait Loci|Epigenetic|Genetic Predisposition to Disease|Genetic Association Studies|Genomics|Transcription Factors 16 c10orf11 27031267 Cleft Palate Craniofac. J. 2016 10.1597/15-171 1 0 0 1 Child|Humans|Female|Child, Preschool|*Cleft Palate|*Speech Delay|Chromosome Deletion|*Hearing Loss, Bilateral|Developmental Disabilities|Karyotyping|Intellectual Disability|Abnormalities, Multiple|Chromosome Banding|*Chromosome Structures|KAT6B protein, human|Histone Acetyltransferases 16 c10orf11 26818737 J. Hum. Genet. 2016 10.1038/jhg.2015.167 0 0 0 1 Humans|*Albinism, Oculocutaneous|Albinism, Ocular|*Homozygote|*Albinism|Mutation|Pedigree|Genetic Predisposition to Disease|Phenotype|Monophenol Monooxygenase|Membrane Transport Proteins|Eyes 16 cdkl1 27206786 Autoimmunity 2016 10.1080/08916934.2016.1183655 6 0 0 103 Humans|Influenza A Virus, H1N1 Subtype|*Narcolepsy|*Autoantibodies|Autoantigens|Influenza Vaccines|Autoimmunity|Influenza, Human|HCRT protein, human|Orexins|HLA-DQ beta-Chains|Sequences, Amino Acid 16 cdkl1 26982032 PLoS Biol. 2016 PMC4794247 10.1371/journal.pbio.1002416 31 19 1 103 Animals|Humans|*Cilia|Proteomics|Meckel syndrome type 1|Ciliary Motility Disorders|Meckel Syndrome, Type 4|Polycystic Kidney Diseases|Caenorhabditis elegans|Encephalocele|Caenorhabditis elegans Proteins|Retinitis Pigmentosa|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|Proteins, Membrane-Associated|Protein Transport|Liver|Polydactyly|Cep290 protein, human|Antigens, Neoplasm 16 EFHD1 27189315 Reprod. Toxicol. 2016 PMC4991937 10.1016/j.reprotox.2016.05.009 9 1 1 78 Child|Pregnancy|Humans|Female|*Proteome|*Placenta|CYP1A1 protein, human|CYP1A1|cytochrome P-450 CYP4B1|Weights, Birth|Smoking|Aromatase|Glutathione Transferase|Downregulation|Up-Regulation|EFHD1 protein, human|Calcium-Binding Proteins 16 EFHD1 26975899 Cell Calcium 2016 10.1016/j.ceca.2016.03.002 7 0 0 78 Mitochondrion|Mitochondrial Membrane Transport Proteins|Membrane Potential, Mitochondrial|Mitochondrial Proteins|Reactive Oxygen Species|Calcium Signaling|Superoxide|Muscle, Skeletal 16 Gon4l 27312530 Cancer Res. 2016 PMC5010501 10.1158/0008-5472.CAN-16-1099 9 29 0 45 Humans|Male|AR protein, human|*Receptors, Androgen|Bladder Cancer|Cell Proliferation|Urothelium|CD24 Antigen|Prognosis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|shRNA|Xenograft|CD24 protein, human|YY1 protein, human|YY1 Transcription Factor|GON4L protein, human|Transcription Factors 16 Gon4l 27036302 Genet. Sel. Evol. 2016 PMC4818447 10.1186/s12711-016-0207-z 5 1 1 45 Animals|Cattle|Child|*Frameshift Mutation|*Dwarfism|Homozygote|Pedigree|Phenotype|Cattle Diseases|Sequence Analysis, DNA|GON4L protein, human|Transcription Factors 16 grwd1 27856536 EMBO Rep. 2016 PMC5210153 10.15252/embr.201642444 14 9 0 169 Humans|ribosomal protein L11|*Tumor Suppressor Protein p53|*Ribosomal Proteins|Proto-Oncogene Proteins c-mdm2|*Tumorigenesis|Cell Nucleolus|Signal Transduction|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Neoplasms|Ubiquitin|Ubiquitination|MDM2 protein, human|GRWD1 protein, human|Carrier Proteins 16 grwd1 27552915 Biochim. Biophys. Acta 2016 10.1016/j.bbamcr.2016.08.008 2 1 0 169 Humans|*Nucleosomes|*Binding Protein|HeLa Cells|*Chromatin Assembly and Disassembly|*DNA Replication|*Cell Cycle Proteins|Histones|Chromatin|Replication Origins|Nuclear Proteins|Protein Binding|CDT1 protein, human|GRWD1 protein, human 16 HMGB4 27608812 Sci Rep 2016 PMC5036535 10.1038/srep32960 2 28 1 26 Animals|Mice|Rats|HMGB Proteins|Chromatin|High Mobility Group Proteins|Histones|Cell Nucleus|*Neurons|Protein Binding|Amino Acid Sequence|Protein Processing, Post-Translational|Cell Differentiation|HMGB4 protein, mouse 16 INIP 27090575 Leuk. Lymphoma 2016 10.3109/10428194.2015.1136740 5 0 0 79 Child|Humans|*Gene Deletion|Comparative Genomic Hybridization|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|*Gene Dosages|Ikaros Transcription Factor|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|DNA Copy Number Variations|*Genetic Testing|Prognosis|B-Lymphocytes|Cohort Studies 16 KIAA1279 26948876 Curr. Biol. 2016 10.1016/j.cub.2016.01.048 28 3 0 164 Humans|Animals|*Kinesin|Caenorhabditis elegans|Synaptic Vesicles|Caenorhabditis elegans Proteins|*Protein Transport|Neurons|Microtubules|Goldberg-Shprintzen megacolon syndrome|Hirschsprung Disease|Craniofacial Abnormalities|Hippocampus|Biological Transport|Protein Binding|TYRP1 protein, human|Membrane Glycoproteins|Motor Activity|KIF1A protein, human|KIAA1279 protein, human 16 KIAA1462 27669027 Am. J. Respir. Crit. Care Med. 2016 PMC5363968 10.1164/rccm.201605-0997OC 15 0 0 64 *Genome-Wide Association Study|*Pulmonary Emphysema|Pulmonary Disease, Chronic Obstructive|*Emphysema|Genetic Predisposition to Disease|Lungs|Polymorphism, Single Nucleotide|Smoking|Tomography, X-Ray Computed 17 KIAA1462 27028815 Mol. Biol. (Mosk.) 2016 10.7868/S0026898415060099 2 0 0 64 Humans|*Myocardial Infarction|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Risk Factors|Hypertension|Hypercholesterolemia 17 LRCH1 28028151 J. Exp. Med. 2016 PMC5206493 10.1084/jem.20160068 13 59 0 44 Mice|Animals|*Encephalomyelitis, Autoimmune, Experimental|DOCK8 protein, human|*Guanine Nucleotide Exchange Factors|*Cell Movement|Lymphocyte Activation|CD4-Positive T-Lymphocytes|Mice, Inbred C57BL|Cells, Cultured|Dock8 protein, mouse 16 LRCH1 27974301 Ann. Rheum. Dis. 2016 PMC5530347 10.1136/annrheumdis-2016-210373 7 2 0 44 *Osteoarthritis, Hip|Genome-Wide Association Study|Osteoarthritis, Knee|Hip Joint|Genetic Predisposition to Disease|*Genetic Testing|Cartilage, Articular|Polymorphism, Single Nucleotide|Gene Frequency|Bone Remodeling 16 LRRC10 28032242 Int. J. Legal Med. 2016 PMC5603906 10.1007/s00414-016-1516-z 2 6 0 52 Humans|*Brugada Syndrome|*Chinese|Gene Frequency|*Pathologies, Molecular|Genetic Predisposition to Disease|Heterozygote|Mutation|Genotype|Polymorphism, Single Nucleotide|Forensic Genetics|Mutation, Missense|Sequencing, Next-Generation|Ethnic Groups|Genetic Screening|Sudden Cardiac Death|Arrhythmia, Cardiac|LRRC10 protein, human|Microfilament Proteins 16 LRRC10 27866268 Mol. Genet. Genomics 2016 10.1007/s00438-016-1274-0 3 0 0 52 *Genome-Wide Association Study|Australia|*Essential Hypertension|SNPs|Genetic Predisposition to Disease|Frequencies, Allele|Linkage Disequilibrium|Case-Control Studies|Genetic Loci|Genotype|DNA|Genomics 16 LRRC10 27536250 Front Physiol 2016 PMC4971440 10.3389/fphys.2016.00337 7 13 1 52 Humans|Mice|Animals|*Cardiomyopathy, Dilated|*Leucine|Cardiomyocytes|Muscle Proteins|leucine-rich repeat proteins|Actin|Actinin|Excitation Contraction Coupling|Sarcomeres|Homozygote|Mice, Knockout|Calcium Signaling|Mutation|Cardiac Disease|LRRC10 protein, human|Microfilament Proteins 16 LRRC10 27460542 Oncol. Rep. 2016 10.3892/or.2016.4965 3 2 0 52 Humans|*RNA, Long Noncoding|*Lung Adenocarcinoma|*Cell Proliferation|A549 Cells|Lung Neoplasms|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Apoptosis|Cell Line, Tumor|Cell Movement|Prognosis|Up-Regulation|mRNA 16 mex3b 27545879 Cell Rep 2016 10.1016/j.celrep.2016.07.062 8 1 0 72 Mice|Animals|IL33 protein, human|*Interleukin-33|Asthma|Bronchial Hyperreactivity|*Inflammation|Ovalbumin|Th2 Cells|Eosinophils|Respiratory Mucosa|*RNA Binding Protein|Lung|Allergens|Mice, Knockout|Mast Cells|Signal Transduction|Cytokines|MEX3B protein, mouse 16 mex3b 27338022 Hepatology 2016 PMC5033702 10.1002/hep.28698 25 67 1 72 Humans|Mice|Animals|*Hepatitis B virus|*Polycomb Repressive Complex 2|Carcinoma, Hepatocellular|HOTAIR long untranslated RNA, human|*RNA, Long Noncoding|Liver Neoplasms|Hepatitis B, Chronic|*Hepatitis B Virus Infection|hepatitis B virus X protein|Trans-Activators|*Carcinogenesis|Epithelial Cell Adhesion Molecule|Downregulation|Hepatocytes|DEAD-box RNA Helicases|MEX3B protein, mouse|RNA-Binding Proteins 16 mex3b 26940660 Cell Res. 2016 PMC4822127 10.1038/cr.2016.29 3 2 0 72 *Toll-Like Receptor 3|*RNA, Double-Stranded|Endosomes|Innate Immune Response|Signal Transduction|Proteolysis 16 mex3b 26823206 Cell Res. 2016 PMC4783467 10.1038/cr.2016.16 13 46 1 72 Humans|Mice|Animals|TLR3 protein, human|*Toll-Like Receptor 3|Poly I-C|RNA, Double-Stranded|Signal Transduction|*RNA Binding Protein|Interferon-beta|Endosomes|Cytokines|Immunity, Innate|Interferons|HEK293 Cells|Antiviral Agents|MEX3B protein, human|MEX3B protein, mouse 16 MLIP 27497767 J Pain 2016 PMC7262688 10.1016/j.jpain.2016.07.003 1 0 0 72 Humans|United States|*Controlled Substances|*Analgesics, Opioid|*Medicaid|Opioid-Related Disorders|Prescription Drug Misuse|Drug Overdose|Drug and Narcotic Control|Expenditures|North Carolina 16 NOC3L 27040346 Yakugaku Zasshi 2016 10.1248/yakushi.15-00260 0 3 0 95 Mice|Animals|*Adipogenesis|*Cell Differentiation|3T3-L1 Cells|Adipocytes|Nuclear Proteins|Cell Cycle Proteins|Basic-Leucine Zipper Transcription Factors|DNA Replication|Replication Origin|Morula|Blastocyst|Fad104 protein, mouse|Fibronectins 16 NOC3L 26902224 Biol. Pharm. Bull. 2016 10.1248/bpb.b15-00954 2 1 0 95 Mice|Humans|Animals|*Adipogenesis|*Resting Phase, Cell Cycle|*S Phase|*Myoblasts|CDKN1B protein, human|*Kip1 Protein, p27|3T3-L1 Cells|Basic-Leucine Zipper Transcription Factors|Adipocytes|Nuclear Proteins|Cell Differentiation|DNA Replication 16 PHACTR4 27608898 Eur Rev Med Pharmacol Sci 2016 3 4 0 152 Humans|*Carcinoma, Hepatocellular|*Actin|*Interleukin-6|*Liver Neoplasms|STAT3 protein, human|*STAT3 Transcription Factor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Hep G2 Cells|Signal Transduction|Cell Movement|Apoptosis|*Phosphoric Monoester Hydrolases|RNA Interference|Xenograft Model Antitumor Assays|*Neoplastic Processes|RNA, Messenger 16 PHACTR4 26850007 Genes Chromosomes Cancer 2016 10.1002/gcc.22345 8 0 0 152 Humans|JAK2 protein, human|*Janus Kinase 2|CD274 protein, human|B7-H1 Antigen|*Genomics|Mutation|Lymphoma|Leukemia|In Situ Hybridization, Fluorescence|Hodgkin Disease|Lymphoma, B-Cell|MHC class II transactivator protein|Nuclear Proteins|Trans-Activators|EEF1A1 protein, human|Peptide Elongation Factor 1 16 PHF23 27890253 Best Pract Res Clin Haematol 2016 10.1016/j.beha.2016.10.002 1 0 0 40 Humans|nuclear pore complex protein 98|Nucleoporin|*Translocation, Genetic|*Leukemia, Myeloid, Acute|Nuclear Pore Complex|Oncogene Proteins, Fusion|*Transcription Factors|Homeodomain Proteins|Gene Fusions|*Genes, Regulator|Malignancies, Hematologic|Cell Transformation, Neoplastic|Cell Nucleus|PHF23 protein, human 16 PHF23 27889185 Cancer Cell 2016 PMC5501282 10.1016/j.ccell.2016.10.019 32 31 0 40 Humans|nuclear pore complex protein 98|Nuclear Pore Complex Proteins|Hox Gene|*Leukemia|Myeloid-Lymphoid Leukemia Protein|Homeodomain Proteins|*Carcinogenesis|Oncogene Proteins, Fusion|Transcription Factors|Histone-Lysine N-Methyltransferase|Cell Transformation, Neoplastic|TYRP1 protein, human|*Membrane Glycoproteins|Chromatin|Gene Expression Regulation, Neoplastic 16 PHF23 27060678 Leuk. Res. 2016 10.1016/j.leukres.2016.03.006 1 0 0 40 Humans|Child|Mice|Animals|nuclear pore complex protein 98|*Transcriptome|Nuclear Pore Complex Proteins|*Leukemia, Myeloid, Acute|Translocation, Genetic|Genes, Homeobox|Homeodomain Proteins|Gene Expression Regulation, Leukemic|Oncogene Proteins, Fusion|Transcription Factors|Transcriptome Analysis|Base Sequence|Stem Cells|PHF23 protein, human 16 PKD1L2 27682262 J. Oral Pathol. Med. 2016 10.1111/jop.12505 0 0 0 9 *Ameloblastoma|*DNA Copy Number Variations|Odontogenic Tumors|Loss of Heterozygosity|*Heterozygote|Mutation|Polymorphism, Single Nucleotide|Microarray Analysis 16 PKD1L2 27711207 PLoS ONE 2016 PMC5053442 10.1371/journal.pone.0164364 7 0 1 9 Humans|Child|*Albuminuria|*Glomerular Filtration Rate|Prospective Studies|*Anemia, Sickle Cell|APOL1 protein, human|Apolipoprotein L1|Hydroxyurea|*Blood Cell Count, White|*Modifier Gene|Lipoproteins, HDL|Genotype|Genetic Variation|CD163 antigen|Receptors, Cell Surface|Genetic Predisposition to Disease|Renal Insufficiency|Genetic Polymorphisms|Antigens, CD 16 PKD1L2 27605020 Int. J. Cancer 2016 10.1002/ijc.30421 2 0 0 9 Humans|*DNA Copy Number Variations|Genome-Wide Association Study|Comparative Genomic Hybridization|Republic of Korea|*Colorectal Cancer|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Genotype|Asian Continental Ancestry Group|PKD1L2 protein, human|*Receptors, G-Protein-Coupled|Case-Control Studies|Genome, Human|*Colonic Neoplasms|Risk Factors 16 PKD1L2 26839365 Development 2016 PMC4813337 10.1242/dev.129254 16 0 0 9 Mice|Animals|Interneurons|Spinal Cord|Neurogenesis|Eye Proteins|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Motoneurons|Gene Expression Regulation, Developmental|GATA2 protein, human|GATA2 Transcription Factor|Ependyma|Forkhead Transcription Factors|Pkd2l1 protein, mouse|Receptors, Cell Surface|Calcium Channels 16 RCBTB1 27608171 Genet. Med. 2016 PMC5392597 10.1038/gim.2016.119 11 6 0 75 *DNA Copy Number Variations|*Retinal Dystrophy|*Retina|Retinal Nonattachment, Nonsyndromic Congenital|*Noncoding RNA|Pedigree 16 RCBTB1 27486781 Am. J. Hum. Genet. 2016 PMC4974088 10.1016/j.ajhg.2016.06.017 5 1 0 75 Humans|*Retinal Dystrophy|Homozygote|Genes, Recessive|Exome|DNA Mutational Analysis|Retinitis Pigmentosa|Pedigree|Mutation|Phenotypes|Retina|Sequencing, Whole Exome|Missense Mutation|Haplotype|*Ubiquitination|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors 16 RCBTB1 27166999 Oncotarget 2016 PMC5095003 10.18632/oncotarget.9216 24 29 1 75 Humans|Female|*Ovarian Cancer|*Carcinoma, Ovarian Epithelial|Cystadenocarcinoma, Serous|Cisplatin|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|3' Untranslated Regions|Cell Proliferation|Cell Movement|Transcription Factors|Tumorigenesis|*Ovary|*Neoplastic Processes|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors|MIRN21 microRNA, human 16 RCBTB1 26908610 Hum. Mol. Genet. 2016 10.1093/hmg/ddw041 11 1 0 75 Humans|*Familial Exudative Vitreoretinopathies|*Retinal Telangiectasis|*Haploinsufficiency|Eye Diseases, Hereditary|Low Density Lipoprotein Receptor-Related Protein-5|Frizzled Receptors|Mutations|Eye Proteins|Pedigree|Asian Continental Ancestry Group|Phenotype|Nerve Tissue Proteins|Mutation, Missense|Retina|beta Catenin|Wnt Pathway|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors 16 SELENON 27645994 J. Biol. Chem. 2016 PMC5104929 10.1074/jbc.M116.756155 39 0 0 179 Humans|Animals|SELENOF protein, human|*Selenoprotein|Selenoprotein P|Selenium|Glutathione Peroxidase|RNA, Messenger|Chickens|Thioredoxin Reductase 19 SH3BGRL3 27233781 Dev. Genes Evol. 2016 10.1007/s00427-016-0552-5 3 0 0 83 Animals|Humans|Adolescent|*Zebrafish|Zebrafish Proteins|Embryo, Nonmammalian|Embryonic Development|Sequence Alignment|Amino Acid Sequence|Gene Expression Regulation, Developmental|In Situ Hybridization|Sequence Homology, Amino Acid|mRNA|Cloning, Molecular|src Homology Domain|SH3BGRL protein, human|Proteins|SH3BGR protein, human|Muscle Proteins 16 STXBP5L 27391584 Genet Test Mol Biomarkers 2016 10.1089/gtmb.2016.0062 4 1 0 36 Humans|*Carcinoma, Hepatocellular|*Hepatitis B, Chronic|*Liver Neoplasms|*Risk Factors|Hepatitis B virus|Liver Cirrhosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Complement Factor B|Haplotypes|Gene Frequency|Case-Control Studies 16 THEMIS2 27992403 Nat. Immunol. 2016 10.1038/ni.3642 3 6 0 62 Receptors, Antigen, B-Cell|*Lymphocyte Activation|B Cells|Germinal Center|Transductions, Signal|src Kinases|Intracellular Signaling Peptides and Proteins|Protein-Tyrosine Kinases|Syk Kinase|GRB2 protein, human|GRB2 Adaptor Protein|Phospholipase C gamma|Self Tolerance 16 TTC39B 27453397 Nat Commun 2016 PMC4962463 10.1038/ncomms12350 7 0 1 84 Humans|Female|*Endometriosis|Genome-Wide Association Study|Vascular Endothelial Growth Factor A|KDR protein, human|*Vascular Endothelial Growth Factor Receptor-2|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Iceland 16 TTC39B 27383786 Nature 2016 PMC4947007 10.1038/nature18628 13 24 1 84 Humans|Mice|Animals|*Liver X Receptor|Genome-Wide Association Study|ABCA1 protein, human|ATP Binding Cassette Transporter 1|ATP Binding Cassette Transporter, Subfamily G, Member 1|Orphan Nuclear Receptors|*Atherosclerosis|SREBF1 protein, human|Sterol Regulatory Element Binding Protein 1|*Steatohepatitis|LDLR protein, human|Low Density Lipoprotein Receptor|Cholesterol|ATP Binding Cassette Transporter, Subfamily G, Member 5|ATP Binding Cassette Transporter, Subfamily G, Member 8|Lipoproteins|Lipoproteins, HDL|Lipoproteins, LDL 16 TTC39B 26840454 Oncotarget 2016 PMC4872719 10.18632/oncotarget.7047 10 21 3 84 Humans|Female|*Carcinoma, Ovarian Epithelial|*Progression-Free Survival|Genome-Wide Association Study|*Ovarian Cancer|Cystadenocarcinoma, Serous|Fallopian Tube Neoplasms|Adenocarcinoma, Clear Cell|Peritoneal Neoplasms|Carboplatin|Prognosis|Endometrial Neoplasms|Paclitaxel|taxane|Taxoids|Antineoplastic Combined Chemotherapy Protocols|PSIP1 protein, human|*Transcription Factors|Drug Resistance, Neoplasm 16 UBR3 27694960 Nat. Genet. 2016 10.1038/ng.3693 69 0 0 148 Humans|Intestinal Microbiota|*Intestines|Bacteria|Feces|*Cohort Studies|Genome-Wide Association Study|Microbiota|SNPs|Bacteroidetes|Host-Pathogen Interactions 16 UBR3 27504967 Elife 2016 PMC4978519 10.7554/eLife.19285 0 8 1 148 Animals|*Hearing|Drosophila Proteins|Drosophila melanogaster|Drosophila|Ubiquitination|Ubiquitin-Protein Ligases|*Hearing Tests 16 UBR3 27331610 Elife 2016 PMC4978524 10.7554/eLife.15258 7 42 1 148 Humans|Animals|*Drosophila|Usher Syndrome, Type Ib|*Usher Syndromes|*E3 Ligase|Drosophila Proteins|Drosophila melanogaster|Myosin|*Mammals|Ubiquitination|Cochlea|Myosin IIA|Cytoskeletal Proteins|MYH9 protein, human|Myosin Heavy Chains|Molecular Motor Proteins 16 UBR3 27195754 PLoS Genet. 2016 PMC4873228 10.1371/journal.pgen.1006054 7 61 1 148 Animals|Mice|Hedgehog Proteins|*Ubiquitination|*Signal Transduction|Drosophila Proteins|Drosophila melanogaster|E3 Ubiquitin Ligase|Drosophila|*Poly A|Zebrafish|Kinesin|UBR3 protein, mouse 16 UNCX 27581094 J. 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Genet. 2015 10.1038/jhg.2015.131 6 0 0 7 Humans|*Molecular Epidemiology|Venezuela|Spinocerebellar Ataxia 17|*Spinocerebellar Ataxias|Spinocerebellar Ataxia 10|Ataxin-3|Trinucleotide Repeat Expansion|Trinucleotide Repeats|Gene Frequency|Spinocerebellar Degenerations|Nerve Tissue Proteins|Mutations|Nuclear Proteins|TATA-Box Binding Protein|Repressor Proteins|*Ethnic Groups|DNA Repeat Expansion|Brazil 18 BCAS4 26593992 Leg Med (Tokyo) 2015 10.1016/j.legalmed.2015.10.003 1 0 0 111 Humans|*Saliva|Forensic Genetics|DNA Fingerprinting|*DNA|Microsatellite Repeats|Polymerase Chain Reaction 16 c10orf11 25712191 Pharmacogenomics 2015 10.2217/pgs.14.171 3 0 0 1 Humans|*Pharmacogenetics|Neoplasm Recurrence, Local|4-hydroxy-N-desmethyltamoxifen|Tamoxifen|CYP2D6|Antineoplastic Agents, Hormonal|Cytochrome P-450 CYP2D6 Inhibitors|Chemotherapy, Adjuvant|Genotype 16 cdkl1 25920913 J. Dermatol. Sci. 2015 10.1016/j.jdermsci.2015.03.020 8 1 0 103 Humans|*RNA Interference|*Down-Regulation|*Melanoma|*Apoptosis|Cell Proliferation|RNA, Small Interfering|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cyclin-Dependent Kinases|Gastric Cancer|Nerve Tissue Proteins|CDKL1 protein, human 16 EFHD1 26540196 PLoS ONE 2015 PMC4634853 10.1371/journal.pone.0142005 9 9 1 78 Dogs|Animals|Mice|*Calcium|*Parvalbumins|*Mitochondria|mitochondrial calcium uniporter|Calcium Channels|Protein, Mitochondrial|Cytosol|Mitochondrial Volume|Ca2+-binding protein-1|Calcium-Binding Proteins|Membrane Potential, Mitochondrial|*Calcium, Dietary|Uncoupling Protein 2|Madin Darby Canine Kidney Cells 16 EPPK1 25617501 J. 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Physiol. 2015 PMC4747898 10.1152/ajpheart.00717.2014 9 1 1 52 Humans|Mice|Animals|Cardiomyocyte|Cardiomegaly|Myocardium|Heart Failure|Muscle Proteins|Actin|Cardiac Disease|Cardiac Ventricles|Mice, Knockout|Pressure, Ventricular|Mechanical Stress|LRRC10 protein, human|Microfilament Proteins 16 LRRC10 26017719 Mol Med Rep 2015 10.3892/mmr.2015.3843 9 0 2 52 Humans|Animals|*Cardiomyopathy, Dilated|*Prevalence|*Mutations|Pedigree|Homeobox Protein Nkx-2.5|Heterozygote|GATA4 Transcription Factor|Mutations, Missense|Homeodomain Proteins|Sequence Alignment|Genetic Predisposition to Disease|Transcription Factors|Base Sequence|Genotype|Phenotype|LRRC10 protein, human|Microfilament Proteins 16 MLIP 26436652 J. Clin. Invest. 2015 PMC4639982 10.1172/JCI82423 10 0 0 72 Humans|Mice|Animals|*Myocytes, Cardiac|Cardiac Hypertrophy|Cardiomyopathy, Dilated|Heart Failure|Signal Transduction|Mice, Knockout|TYRP1 protein, human|*Membrane Glycoproteins|*Protective Agents|Lamin A-C|*Homeostasis|MLIP protein, mouse|Carrier Proteins|Nuclear Proteins 16 MLIP 26359501 J. Biol. Chem. 2015 PMC4646324 10.1074/jbc.M115.678433 6 1 0 72 Mice|Animals|*Proto-Oncogene Proteins c-akt|Genome-Wide Association Study|MTOR protein, human|*Mammalian Target of Rapamycin|Cardiomegaly|Signal Transduction|Myocardium|Myocytes, Cardiac|Phosphorylation|*Lamins|Isoproterenol|*Adaptation, Physiological|MLIP protein, mouse|Carrier Proteins|Nuclear Proteins 16 ogfod1 26118662 Cell. Mol. Life Sci. 2015 10.1007/s00018-015-1978-z 12 0 2 123 *Dioxygenases|*Ketoglutaric Acids|*Oxygen|Histones|Chromatin|Epigenesis, Genetic|*Energy Metabolism|DNA Methylation|Krebs Cycle|Jumonji Domain-Containing Histone Demethylases|Hydroxylases|DNA|Lysine|*Homeostasis|Succinate|*Physiological Phenomena|Iron 16 ogfod1 25909288 Oncotarget 2015 PMC4637303 10.18632/oncotarget.3683 1 21 0 123 Nuclear Proteins|Cell Cycle Proteins|Gene Expression Regulation, Neoplastic|Cell Proliferation|mRNA|RNA Interference|Gene Knockdown Techniques|Cell Line, Tumor|Cell Cycle Checkpoints|Protein Biosynthesis|Cell Nucleus|Prognosis 16 ogfod1 25728928 Structure 2015 PMC4396695 10.1016/j.str.2015.01.014 12 13 1 123 Humans|*Prolyl Hydroxylases|*Ribosomes|Prolyl-Hydroxylase Inhibitors|*Oxygenases|Hydroxylation|proline, 2-oxoglutarate 3-dioxygenase|Procollagen-Proline Dioxygenase|Protein Processing, Post-Translational|Mixed Function Oxygenases|2-Oxoglutarate|Saccharomyces cerevisiae|*Oxidation-Reduction|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins 16 PHACTR4 26619149 Nat. Cell Biol. 2015 PMC5333577 10.1038/ncb3275 20 10 0 152 Humans|Mice|Animals|*miRNAs|*Squamous Cell Carcinoma|Gene Expression Regulation, Neoplastic|Cell Proliferation|Genes, Tumor Suppressor|Cell Cycle|*Disease Progression|Cell Line, Tumor|Cell Movement|Apoptosis|MIRN21 microRNA, human 16 PHF23 26066811 J Hematol Oncol 2015 PMC4467064 10.1186/s13045-015-0167-8 3 1 0 40 Child|Humans|nuclear pore complex protein 98|*Transcriptome|*Leukemia, Myeloid, Acute|Nuclear Pore Complex Proteins|Translocation, Genetic|Oncogene Proteins, Fusion|*Transcriptome Sequencing, Whole|Homeodomain Proteins|*Genes, Regulator|Gene Expression Profiling|Transcription Factors|Cytogenetic Abnormality|Cohort Studies|PHF23 protein, human 16 PHF23 25835095 Expert Rev Proteomics 2015 10.1586/14789450.2015.1033409 16 0 0 40 Humans|Male|*Proteomics|*Translational Medical Research|Phylogeny|*Transcription Factors|*Epigenesis, Genetic|Repressor Proteins|*Epigenetics|Amino Acid Sequence|Neoplasms|Mutations|MLL5 protein, human|ASXL1 protein, human|BAP1 protein, human|Tumor Suppressor Proteins|Ubiquitin Thiolesterase|ASXL2 protein, human|ASXL3 protein, human|PHF8 protein, human 16 SCAPER 25935106 J. Allergy Clin. Immunol. 2015 PMC4562879 10.1016/j.jaci.2015.03.030 9 0 2 22 Child|Humans|Adult|*Genome-Wide Association Study|*Dermatitis, Atopic|Republic of Korea|Genetic Predisposition to Disease|*Eczema|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Asian Continental Ancestry Group|Genotype|Case-Control Studies|Immunoglobulin E 17 SH3BGRL3 26286913 Clin. Cancer Res. 2015 10.1158/1078-0432.CCR-14-3308 10 5 1 83 Humans|*Prognosis|*Carcinoma, Transitional Cell|EGFR protein, human|*Epidermal Growth Factor Receptor|*Urologic Neoplasms|Urinary Bladder Neoplasms|Urothelium|Signal Transduction|Cell Movement|Proto-Oncogene Proteins c-akt|TYRP1 protein, human|*Membrane Glycoproteins|Cell Proliferation|Biomarkers, Tumor|Cell Line, Tumor|Kaplan-Meier Estimate|SH3BGRL3 protein, human|Intracellular Signaling Peptides and Proteins 16 TTC39B 25920552 Eur. J. Hum. Genet. 2015 PMC4681116 10.1038/ejhg.2015.63 5 1 0 84 Humans|Female|*Lipids|ATP Binding Cassette Transporter, Subfamily G, Member 8|ATP Binding Cassette Transporter, Subfamily G, Member 5|Lipoproteins|Single Nucleotide Polymorphisms|Genotype|Cholesterol|Gene Frequency|ATP-Binding Cassette Transporters|*Obesity|Cholesterol, HDL|Gallstones|*Gall Bladder Disease 16 UBR3 26383956 Science 2015 10.1126/science.aac5677 25 5 3 148 Animals|*Proteasome Endopeptidase Complex|Transcription Factors|Drosophila Proteins|*Protein Processing, Post-Translational|Drosophila melanogaster|DNA-Binding Proteins|Ubiquitin|peptide B|Ubiquitination|Drosophila|Hedgehog Proteins|Ubiquitin-Conjugating Enzymes|Gene Expression Regulation, Developmental|Ubiquitin-Protein Ligases|RNA Interference|Amino Acid Sequence|Signal Transduction 16 UBR3 26186006 PLoS ONE 2015 PMC4505843 10.1371/journal.pone.0133422 7 1 2 148 Humans|*Genome-Wide Association Study|*Intracranial Aneurysm|Portugal|SNPs|Genetic Predisposition to Disease|Alleles|Asian Continental Ancestry Group|Genotype|Subarachnoid Hemorrhage|Case-Control Studies|Risk Factors|PRDM9 protein, human|Histone-Lysine N-Methyltransferase 16 UBR3 26059563 J. Cell. Mol. Med. 2015 PMC4568919 10.1111/jcmm.12588 4 44 1 148 Rats|Humans|Animals|*Ubiquitin-Protein Ligase E3|HEK293 Cells|recognins|Ubiquitin|NAV1.5 Voltage-Gated Sodium Channel|Proteasome|Cardiomyocytes|Ubiquitylation|Potential, Action|Cardiac Arrhythmias|Protein Binding|Sodium 16 VPS13D 25896417 J Innate Immun 2015 PMC6738836 10.1159/000381265 1 1 0 60 18 ARL4D 25433550 Mol. Genet. Genomics 2014 10.1007/s00438-014-0960-z 5 0 2 72 Mice|Animals|*miRNAs|*mRNA|*Podocytes|*Cell Differentiation|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Regulatory Networks|Gene Expression Regulation|Downregulation|Gene Ontology|Quantitative Real Time Polymerase Chain Reaction|Up-Regulation|*Organogenesis|Luciferase|DICER1 protein, human|Ribonuclease III|DEAD-box RNA Helicases|Glrx protein, mouse 16 BCAS4 24395524 J. Pathol. 2014 PMC4013428 10.1002/path.4325 39 5 6 111 Humans|Comparative Genomic Hybridization|Carcinoma, Ductal, Breast|Receptors, Estrogen|*Genomics|Biomarkers, Tumor|Mutations|Carcinoma, Papillary|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Phenotype|*Gene Expression|DNA Mutational Analysis|Breast Cancer|FAF1 protein, human|Adaptor Proteins, Signal Transducing 16 c10orf11 25093188 Biomed Res Int 2014 PMC4100393 10.1155/2014/905472 20 17 2 1 Humans|Oculocutaneous albinism type 1|*Albinism, Oculocutaneous|Oculocutaneous albinism type 1B|*DNA Mutational Analysis|TYRP1 protein, human|Membrane Glycoproteins|Oxidoreductases|Mutation|Membrane Transport Proteins|Alleles|Monophenol Monooxygenase|Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Antigens, Neoplasm|Melanin 16 EFHD1 24861485 Cancer Med 2014 PMC4302673 10.1002/cam4.273 9 8 4 78 Humans|*Colorectal Cancer|*Promoter Regions, Genetic|DNA Methylation|CpG Islands|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|*Protein Processing, Post-Translational|Decitabine|PCR|PPP1R3C protein, human|Carrier Proteins|Phosphoprotein Phosphatases|EFHD1 protein, human|Calcium-Binding Proteins 16 EPPK1 25526346 Nat Commun 2014 10.1038/ncomms6696 0 0 1 76 Humans|Epigenesis, Genetic|*Intrahepatic Cholangiocarcinoma|*Bile Ducts, Intrahepatic|Bile Duct Neoplasms|*Mutations|*Liver Neoplasms|Isocitrate Dehydrogenase|ARID1A protein, human|Nuclear Proteins|Tumor Suppressor Protein p53|Genes, ras|Transcription Factors|Signal Transduction|China 16 EPPK1 25427637 Tumour Biol. 2014 10.1007/s13277-014-2772-5 10 0 1 76 Humans|Female|*Two-Dimensional Difference Gel Electrophoresis|*Proteomics|*Uterine Cervical Neoplasms|Early Detection of Cancer|Electrophoresis, Gel, Two-Dimensional|Carcinoma, Squamous Cell|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Biomarkers, Tumor|Neoplasm Proteins|Plasma Proteins|Blotting, Western|*Plasma|ELISA|MASP2 protein, human|Mannose-Binding Protein-Associated Serine Proteases 16 FOXS1 25289806 Mol. Cell. Endocrinol. 2014 PMC4262703 10.1016/j.mce.2014.09.029 10 5 0 119 Female|Male|Humans|Mice|Animals|*Ferrets|*DBA Mice|*Adrenal Cortex Neoplasms|*Gonadectomy|Adrenal Cortex|*Biomarkers|Gonads|Immunohistochemistry|GATA4 Transcription Factor|Cell Differentiation|Ovariectomy|In Situ Hybridization 16 Gon4l 24954872 Lung Cancer 2014 10.1016/j.lungcan.2014.05.020 0 0 1 45 Humans|*Germ-Line Mutation|Genome-Wide Association Study|*Non-Smokers|*Lung Adenocarcinoma|Lung Cancer|Adenocarcinoma|Genetic Predisposition to Disease|Carcinoma, Squamous Cell|Genotype|Biomarkers, Tumor|Smoking 16 LRCH1 24850809 Circ Cardiovasc Genet 2014 PMC4141024 10.1161/CIRCGENETICS.113.000373 16 0 2 44 Genome-Wide Association Study|Genetic Loci|*Complement Factor B|Nodes, Atrioventricular|Polymorphism, Single Nucleotide|Electrocardiography|Genotype|Heart Rate 16 LRCH1 24478024 Genes Chromosomes Cancer 2014 10.1002/gcc.22144 12 1 5 44 *Tumors, Colorectal|Adenoma|*Oncogene|*Gene Dosage|*Disease Progression|Carcinoma|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Chromosome Aberrations 16 LRP3 24951786 Appl. 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Microbiol. 2014 PMC4136089 10.1128/AEM.01393-14 7 1 0 44 *Sinorhizobium meliloti|Gene Expression Regulation, Bacterial|Operon|Nitrogen Fixation|Alfalfa|Symbiosis|Bacterial Proteins|Transcription Factors|Transcription Start Sites|Lipopolysaccharides|Promoter Regions, Genetic|*Carbohydrate Metabolism|Rhizobium 16 mex3b 24803656 Development 2014 10.1242/dev.108514 5 0 1 72 Male|Mice|Animals|Sertoli Cells|Seminiferous Epithelium|Blood-Testis Barrier|Seminiferous Tubules|*RNA Binding Protein|N-Cadherin|Germ Cells|Signal Transduction|beta Catenin|GJA1 protein, human|Connexin43|Cell Communication|Carrier Proteins|MEX3B protein, mouse|Rap1GAP protein, mouse|GTPase-Activating Proteins 16 MLIP 25351973 J Manag Care Spec Pharm 2014 PMC6833956 10.18553/jmcp.2014.20.11.1122 3 0 0 72 Humans|United States|*Pharmacists|*Medicaid|North Carolina|Community Pharmacy Services|Pharmacies|Opioids|Drug and Narcotic Control|Drug Overdose|Attitude of Health Personnel 16 ogfod1 25294124 Neurogenetics 2014 10.1007/s10048-014-0425-x 5 0 1 123 Humans|*Exome|*Parkinson Disease|SNPs|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Gene Frequency|Mutations|Whole Exome Sequencing|Odds Ratio|Risk Factors|Sardinia|Portugal|Spain|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins 16 ogfod1 24550463 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC3964085 10.1073/pnas.1314485111 22 4 1 123 Humans|Animals|*Prolyl Hydroxylase|*Drosophila|*Ribosomes|Ribosomal Protein|*Procollagen-Proline Dioxygenase|Hydroxylation|Protein Biosynthesis|Protein Processing, Post-Translational|2-Oxoglutarate|Saccharomyces cerevisiae|Oxygenases|*Homeostasis|RNA, Messenger|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins 16 ogfod1 24550462 Proc. Natl. Acad. Sci. U.S.A. 2014 PMC3964080 10.1073/pnas.1311750111 53 1 3 123 Animals|Humans|*Hydroxylation|Saccharomyces cerevisiae|*Ribosomes|Protein Biosynthesis|Ribosomal Proteins|Prolyl 4-Hydroxylase|Stop Codon|Carrier Proteins|*Eukaryotic Cells|Schizosaccharomyces pombe|Transcription Factor|Catalytic Domain|OGFOD1 protein, human|Nuclear Proteins 16 ogfod1 24550447 Proc. Natl. Acad. Sci. 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Cell Biol. 2014 10.1007/s00418-014-1220-3 3 4 1 152 Animals|Mice|*Intermediate Filaments|*Astrocytes|*Actins|*Neural Stem Cells|NES protein, human|Nestin|Glial Fibrillary Acidic Protein|Neurogenesis|Neurons|*Adult Stem Cells|Cell Differentiation|Cells, Cultured|*Phosphoric Monoester Hydrolases|Phosphorylation|Immunohistochemistry 16 PHF23 25484098 Autophagy 2014 PMC4502667 10.4161/auto.36439 7 4 1 40 *E3 Ligase|*Ubiquitination|*Cellular Autophagy|Ubiquitin|Signal Transduction|*Homeodomain Proteins|*Plant Proteins|*Transcription Factors 16 PHF23 24535671 Cancer Discov 2014 PMC4018760 10.1158/2159-8290.CD-13-0419 23 36 0 40 Humans|Mice|Animals|nuclear pore complex protein 98|histone H3 trimethyl Lys4|*Histones|Nuclear Pore Complex Proteins|Proteins, Homeo Domain|*Transcription Factors|Oncogene Proteins, Fusion|Myeloid Ecotropic Viral Integration Site 1 Protein|Genes, Homeobox|Leukemia, Myeloid, Acute|Chromatin|*Oncogene Proteins|Translocation, Genetic|*Genes, Regulator|Cell Transformation, Neoplastic|Chromatin Immunoprecipitation|PHF23 protein, human 16 PKD1L2 24756726 Handb Exp Pharmacol 2014 10.1007/978-3-642-54215-2_27 22 0 1 9 Humans|Animals|polycystic kidney disease 1 protein|*TRPP Cation Channels|Polycystic Kidney, Autosomal Dominant|Ion Channel|Amino Acid Sequence|*Genes, Regulator|Signal Transduction|Ion Transport|Mutation|Cell Membrane|Phenotypes|PKD1L1 protein, human|Membrane Proteins|PKD1L3 protein, human|PKDREJ protein, human|Receptors, Cell Surface 16 SCAPER 25294124 Neurogenetics 2014 10.1007/s10048-014-0425-x 5 0 1 22 Humans|*Exome|*Parkinson Disease|SNPs|Genetic Predisposition to Disease|Genotype|Case-Control Studies|Gene Frequency|Mutations|Whole Exome Sequencing|Odds Ratio|Risk Factors|Sardinia|Portugal|Spain|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins 17 SCAPER 24622687 Genes Immun. 2014 PMC4308959 10.1038/gene.2014.11 1 1 0 22 Humans|*Hepacivirus|Genome-Wide Association Study|*Hepatitis C|Single Nucleotide Polymorphisms|European Continental Ancestry Group|African Continental Ancestry Group|African Americans|Genetic Predisposition to Disease|Allele 17 SELENON 24454231 Acta Crystallogr Sect E Struct Rep Online 2014 PMC3885055 10.1107/S1600536813029978 0 0 0 179 pyridine|*Pyridines|Bandages|Frailty 19 STXBP5L 25504045 Hum. Mol. Genet. 2014 10.1093/hmg/ddu614 0 1 0 36 Animals|Mice|Humans|*Homozygote|*Mutation|Exome|*Neurodegenerative Disorder|Pedigree|Optic Atrophy|Siblings|Mutation, Missense|Sequence Analysis, DNA|FMNL3 protein, human|Formins|STXBP5L protein, human|Carrier Proteins|STXBP5L protein, mouse|R-SNARE Proteins|FMNL3 protein, mouse 16 STXBP5L 25002582 J. Biol. Chem. 2014 PMC4155689 10.1074/jbc.M114.575985 0 6 1 36 *Insulin Secretion|*Phosphorylation|Proteomics|Exocytosis|R-SNARE Proteins|Syntaxin 1|Insulin|Glucose|Nerve Tissue Proteins|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Ubiquitination|E3 Ubiquitin Ligase 16 STXBP5L 24744148 Brain Struct Funct 2014 10.1007/s00429-014-0766-0 3 0 1 36 Mice|Animals|*Motor Endplate|*Neurotransmission|Neuromuscular Junction|Receptors, Cholinergic|SNARE Proteins|Acetylcholine|Nerve Tissue Proteins|Disease Models, Animal|tomosyn protein, mouse|R-SNARE Proteins|STXBP5L protein, mouse 16 THEMIS2 24907343 J. Immunol. 2014 PMC4082722 10.4049/jimmunol.1400943 5 25 0 62 Mice|Animals|*Lymphocyte Activation|*Responses, Antibody|Germinal Center|B Cells|Plasma Cells|Cell Differentiation|GRB2 protein, human|GRB2 Adaptor Protein|*Hematopoiesis|VAV1 protein, human|Proto-Oncogene Proteins c-vav|Lymphoid Tissue|Intracellular Signaling Peptides and Proteins|Themis2 protein, mouse 16 THEMIS2 24826199 J Ovarian Res 2014 PMC4018944 10.1186/1757-2215-7-42 0 4 0 62 Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Single Nucleotide Polymorphisms|Frequencies, Allele|Genetic Predisposition to Disease|Allele|Genotype-Phenotype Association|Genotype|Case-Control Studies|Heterozygote|Neoplasm Proteins 16 UBR3 25146930 Cell Death Differ. 2014 PMC4227149 10.1038/cdd.2014.115 7 7 2 148 Animals|*Drosophila|BIRC3 protein, human|*Inhibitor of Apoptosis Protein 1|*E3 Ligase|Caspases|*Apoptosis|Drosophila Proteins|Inhibitor of Apoptosis Proteins|Drosophila melanogaster|Cell Death|Ubiquitination|Proteolysis|Cell Line 16 UBR3 24979338 Gene 2014 10.1016/j.gene.2014.06.010 9 0 1 148 *MicroRNAs|*Messenger RNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Gene Expression Profiling 16 UNCX 25294938 Development 2014 PMC7055718 10.1242/dev.105981 13 6 0 15 Mice|Animals|Hedgehog Proteins|*Chondrogenesis|*Somites|Glycogen Synthase Kinase 3|*Embryonic Stem Cells|Chondrocytes|Mesoderm, Paraxial|Bone Morphogenetic Proteins|Cell Differentiation|Chir 99021|Pyridines|SOX9 protein, human|SOX9 Transcription Factor|Cartilage|Pluripotent Stem Cells|Pyrimidines|Wnt Signaling Pathway|Transforming Growth Factor beta 16 UNCX 24514266 Mech. Dev. 2014 PMC3943791 10.1016/j.mod.2013.10.001 6 11 1 15 *Follistatin|Somite|noggin protein|*Carrier Proteins|Body Patterning|Mesoderm, Paraxial|Transcription Factors|Gene Expression Regulation, Developmental|Spine|Chondrogenesis|Signal Transduction|*Bone and Bones 16 ATXN8 24269018 Neurobiol. Aging 2013 PMC3880650 10.1016/j.neurobiolaging.2013.09.024 8 0 2 7 Humans|*Amyotrophic Lateral Sclerosis|ATXN2 protein, human|Ataxin-2|Ataxins|Trinucleotide Repeat Expansion|Nerve Tissue Proteins|polyglutamine|Peptides|Genetic Predisposition to Disease|*Nucleotides|C9orf72 protein, human|C9orf72 Protein|ATXN10 protein, human|Ataxin-10 18 ATXN8 24040107 PLoS ONE 2013 PMC3770663 10.1371/journal.pone.0073885 2 2 0 7 Humans|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Spinocerebellar ataxia 8|Spinocerebellar Degenerations|Nerve Tissue Proteins|Open Reading Frames|RNA, Long Noncoding|*Polyribosomes 18 ATXN8 23791884 Cancer Lett. 2013 10.1016/j.canlet.2013.06.013 361 0 42 7 Humans|*RNA, Long Non-Coding|Cancers 18 c10orf11 24096233 Gene 2013 10.1016/j.gene.2013.09.053 2 1 0 1 Humans|*Mutation Rate|Italy|*Albinism, Oculocutaneous|Mutations|Exons|Pedigree|Membrane Transport Proteins|Phenotype|Monophenol Monooxygenase|Antigens, Neoplasm|Eyes|SLC45A2 protein, human 16 c10orf11 24066960 Pigment Cell Melanoma Res 2013 10.1111/pcmr.12167 43 0 2 1 Humans|Dilution, Pigmentary|Albinism, Oculocutaneous|*Albinism|Albinism, Ocular|Phenotypes|Chediak-Higashi Syndrome|Hypopigmentation|Mutation|Membrane Transport Proteins|Eyes|Skin|Pigmentation 16 c10orf11 23395477 Am. J. Hum. Genet. 2013 PMC3591853 10.1016/j.ajhg.2013.01.006 22 0 2 1 Animals|Humans|*Albinism|*Mutations|*Pigmentation|Homozygote|Genes, Recessive|DNA Mutational Analysis|Mutation, Nonsense|Phenotype|Melanocytes|Zebrafish|*Cell Differentiation|Cohort Studies|Faeroe Islands|Lithuania 16 EFHD1 23909416 Monoclon Antib Immunodiagn Immunother 2013 PMC3733322 10.1089/mab.2013.0014 4 0 0 78 Humans|Mice|Animals|*EF Hand Motifs|*Calcium-Binding Proteins|Leukocytes, Mononuclear|B Cells|Monocytes|Antibodies, Monoclonal|Cell Line|Signal Transduction|Protein Domains|EFHD2 protein, human|EFHD1 protein, human|EFHD2 protein, mouse 16 EFHD1 23431751 Genet. Couns. 2013 0 0 0 78 Humans|Female|Child, Preschool|*Intellectual Disability|*Agenesis of Corpus Callosum|*Dwarfism|Chromosome Deletion|Abnormalities, Multiple|Haploinsufficiency|Phenotype|HDAC4 protein, human|Repressor Proteins|Histone Deacetylases|EFHD1 protein, human|Calcium-Binding Proteins 16 EPPK1 23549274 Eur. J. Hum. Genet. 2013 PMC3831074 10.1038/ejhg.2013.58 10 0 1 76 Humans|Mice|Animals|VACTERL association|DNA Copy Number Variations|Limb Deformities, Congenital|Heart Defects, Congenital|Anus, Imperforate|Spine|Trachea|Esophagus|Anal Canal|Anorectal Malformations|Esophageal Atresia|Tracheoesophageal Fistula|Kidney|Phenotype|Abnormalities, Multiple|Radius|Renal Adysplasia|*Chromosome Structures 16 Gon4l 23608756 Lab. Invest. 2013 PMC3669254 10.1038/labinvest.2013.62 4 5 2 45 Humans|Mice|Animals|Infant|*Disease Models, Animal|*Cancer, Salivary Gland|Myoepithelioma|Adenoma, Pleomorphic|Immunohistochemistry|Carcinomas|*Cell Differentiation|Salivary Glands|*Strain, Mutant Mouse|Glands, Parotid|Epithelial Cells|Biomarkers, Tumor|Diagnosis, Differential|GON4L protein, human|Transcription Factors 16 HMGB4 23303677 Biol. Reprod. 2013 10.1095/biolreprod.112.103788 14 0 1 26 Cattle|Animals|Male|*Ribonucleic Acid|*Cryopreservation|Spermatozoa|Conception|mRNA|Fertility|Gene Expression Profiling|Sequencing, RNA|Poly A|Illumina Sequencing|Nucleic Acid Hybridization 16 INIP 23331100 Child Dev 2013 PMC3633670 10.1111/cdev.12052 13 0 0 79 Humans|Young Adult|Adolescent|*Linguistic|Speech|Movement|Kinematics|Jaw|Speech Production Measurement|Lip|Cognition 16 KIAA1279 23427148 Hum. Mol. Genet. 2013 10.1093/hmg/ddt083 8 2 1 164 Humans|Goldberg-Shprintzen megacolon syndrome|*Hirschsprung Disease|*Craniofacial Abnormalities|Microtubules|Tubulin|Binding Protein|Nerve Tissue Proteins|Intellectual Disability|*Protein Binding|Cytoskeleton|Neurons|Actin|Mutations|Neurogenesis|Neuroblastoma|KIAA1279 protein, human 16 KIAA1462 24349219 PLoS ONE 2013 PMC3861372 10.1371/journal.pone.0082194 6 4 2 64 *Alzheimer Disease|*Coronary Artery Disease|Neurodegenerative Diseases|ApoE4|*Heterozygote|Genetic Predisposition to Disease|Alleles|Genotype|Polymorphism, Single Nucleotide|Apolipoproteins E|Genetic Testing|Genetic Linkage|Gene Expression|Brain 17 KIAA1462 23774303 Gynecol. Oncol. 2013 PMC4083840 10.1016/j.ygyno.2013.06.007 13 1 4 64 Humans|Female|*Ovary|*Exome|*Cystadenoma, Serous|Cystadenocarcinoma, Serous|Proto-Oncogene Proteins B-raf|ras Proteins|Mutation|Ovarian Neoplasms|*Precancerous Conditions|Sequence Analysis 17 LRP3 23827521 Comp. Biochem. Physiol., Part A Mol. Integr. 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Biophys. Res. Commun. 2013 10.1016/j.bbrc.2013.07.061 0 0 0 95 Mice|Animals|*Adipogenesis|3T3-L1 Cells|Adipocytes|*Embryonic Development|Basic-Leucine Zipper Transcription Factors|Nuclear Proteins|Cell Cycle Proteins|Cell Differentiation|DNA Replication|*Blastocyst|Cell Nucleus 16 PHACTR4 23319639 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3562831 10.1073/pnas.1221385110 6 2 1 152 Animals|*Cell Transformation, Neoplastic|Cell Proliferation|*Tumorigenesis|Tumor Suppressor Proteins|Gene Expression Regulation, Neoplastic|Mammary Neoplasms, Experimental|Cell Line, Tumor|RNAi|Signal Transduction|*Genes, Tumor Suppressor 16 PKD1L2 24336289 Nature 2013 PMC4073646 10.1038/nature12832 114 8 15 9 Mice|Animals|Hedgehog Proteins|*Cilia|*Calcium Channel|Patched Receptors|Smoothened Receptor|PKD1L2 protein, human|Receptors, G-Protein-Coupled|Signal Transduction|Receptors, Cell Surface|polycystic kidney disease 1 protein|TRPP Cation Channels|Organelles|Pkd2l1 protein, mouse|Pkd2l2 protein, mouse|Membrane Glycoproteins 16 RCBTB1 24202307 Arterioscler. Thromb. Vasc. Biol. 2013 PMC4380266 10.1161/ATVBAHA.113.302706 9 2 1 75 Humans|*Carotid Intima-Media Thickness|Carotid Artery Diseases|Carotid Arteries|European Continental Ancestry Group|Genetic Predisposition to Disease|African Americans|Polymorphism, Single Nucleotide|*Smoking|Hispanic Americans|Plaque, Atherosclerotic|Gene Frequency|Risk Factors|*Tobacco Smoking|Phenotype|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors 16 RCBTB1 23689287 Oncogenesis 2013 PMC3671123 10.1038/oncsis.2013.10 20 12 4 75 Humans|*Liposarcoma|Cell Differentiation|Proto-Oncogene Proteins c-mdm2|Gene Amplification|Cell Dedifferentiation|Apoptosis|Tumorigenesis|Cell Proliferation|MicroRNAs|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors|MIRN26A microRNA, human 16 STXBP5L 23637638 PLoS Genet. 2013 PMC3636136 10.1371/journal.pgen.1003474 36 10 6 36 Humans|Male|Animals|Mice|*RNA Precursors|*RNA Splicing|KHDRBS3 protein, human|RNA Binding Protein|Splicings, Alternative|Exons|RNA, Messenger|Adaptor Proteins, Signal Transducing|*Brain|Brachyury protein|*Fetal Proteins|*T-Box Domain Proteins|STXBP5L protein, mouse|R-SNARE Proteins 16 THEMIS2 23474491 Cancer Lett. 2013 10.1016/j.canlet.2013.02.049 2 1 0 62 Humans|Female|*Ovarian Cancer|Apoptosis|Cell Line, Tumor|*Carcinoma, Ovarian Epithelial|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Intracellular Signaling Peptides and Proteins|Estradiol|Upregulation|Cell Proliferation|RNA, Small Interfering|Gene Expression Profiling|RNA, Messenger|KLK10 protein, human|Kallikreins 16 UNCX 23401059 Dev. Dyn. 2013 10.1002/dvdy.23945 5 0 1 15 Animals|*Xenopus laevis|PAX1 transcription factor|*Paired Box Transcription Factors|Somites|*Embryogenesis|Gene Expression Regulation, Developmental|PAX9 Transcription Factor|Amino Acid Sequence|In Situ Hybridization 16 ARL4D 22927989 PLoS ONE 2012 PMC3424131 10.1371/journal.pone.0043552 8 24 1 72 Humans|*Membrane Potentials|*Mitochondria|ADP-Ribosylation Factor|*Signal Transduction|Plasma Membrane|Guanosine Triphosphate|HeLa Cells|Protein Transport|Cell Nucleus|Protein Binding|Proteins|Nuclear Localization Signals|*Biophysical Phenomena|ARL4C protein, human 16 ATXN8 22577844 Eur. J. Neurol. 2012 10.1111/j.1468-1331.2012.03749.x 2 1 0 7 Humans|*Parkinson Disease|*Promoter Regions, Genetic|Genetic Predisposition to Disease|*Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Case-Control Studies 18 BCAS4 23036331 Methods 2012 10.1016/j.ymeth.2012.09.013 7 0 2 111 *Gene Fusions|Sequencing, Next-Generation|Sequence Analysis, RNA|Gene Expression Profiling|Base Sequence|Transcriptome|Cell Line, Tumor|Oncogene Proteins, Fusion|Gene Expression Regulation, Neoplastic|RNA, Messenger 16 BCAS4 22740462 Electrophoresis 2012 10.1002/elps.201100711 6 0 1 111 Male|hydrogen sulfite|*DNA Methylation|*Sulfites|CpG Islands|Epigenetic|Forensic Genetics|Nested PCR|Sequence Analysis, DNA|Semen|Cytosine|Genetic Markers|Saliva|Sperm|Body Fluids|High-Throughput Nucleotide Sequencing 16 BCAS4 22377736 Dis. Markers 2012 PMC3826591 10.3233/DMA-2011-0877 16 0 1 111 *Stomach Neoplasms|*Methylations, DNA|Promoter Regions, Genetic|Gastric Mucosa|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Polymerase Chain Reaction|Stomach 16 cdkl1 22804458 Cancer Biother. Radiopharm. 2012 10.1089/cbr.2012.1198 5 0 0 103 Humans|Vascular Endothelial Growth Factor A|*Cyclin-Dependent Kinases|Receptors, Estrogen|progesterone receptor B|Progesterone Receptor|Cell Proliferation|Short Hairpin RNA|mRNA|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MCF 7 Cells|Down-Regulation|Apoptosis|Transfections|Cell Cycle|Protein-Serine-Threonine Kinases|Cyclins 16 cdkl1 22369697 Acta Oncol 2012 10.3109/0284186X.2012.665611 8 1 2 103 *Stomach Neoplasms|Cell Proliferation|RNA, Small Interfering|Gastric Mucosa|Apoptosis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|RNA, Messenger|Cyclin-Dependent Kinases 16 FOXS1 22911753 PLoS ONE 2012 PMC3401116 10.1371/journal.pone.0041146 11 11 0 119 Male|Mice|Animals|*Sertoli Cells|*MicroRNAs|*Androgens|Spermatogenesis|Testis|Receptors, Androgen|Testosterone|Gene Expression Profiling|Gene Expression 16 Gon4l 23175445 Hum. Mol. Genet. 2012 PMC3554200 10.1093/hmg/dds481 19 0 3 45 Humans|*siRNA|*MicroRNAs|HEK293 Cells|Sequencing, RNA|Base Sequence|Argonaute Proteins|High-Throughput Nucleotide Sequencing|Transfer RNA|Nucleic Acid Conformation|Small Noncoding RNA|*RNA, Double-Stranded|Small Nucleolar RNA|Co-Immunoprecipitation|Gene Library|*Skin 16 HMGB4 22901013 Biochemistry 2012 PMC3448822 10.1021/bi300649v 11 0 3 26 Humans|Male|Animals|*Cisplatin|DNA Adducts|High Mobility Group Proteins|Transcription Factors|Testicular Germ Cell Tumor|Testicular Neoplasms|HMGB Proteins|Neoplasms, Germ Cell and Embryonal|HMGB1|Protein Binding|DNA Damage|Amino Acid Sequence|DNA 16 HMGB4 22655796 Cancer Biother. Radiopharm. 2012 PMC3375072 10.1089/cbr.2012.1199 10 0 2 26 *Retinoblastoma|Retinoblastoma Protein|*Radiosensitivity|Binding Sites|Amino Acid Sequence|Papillomavirus E7 Proteins|Protein Binding|*Cell Proliferation|HMGB1 Protein|Retinal Neoplasms 16 INIP 22872638 J. Biol. Chem. 2012 PMC3464515 10.1074/jbc.M112.387944 10 1 0 79 p31 integrase protein, Human immunodeficiency virus 1|*HIV Integrase|transportin SR2|*beta Karyopherins|HIV-1|Nuclear Import|Virus Replication|Reverse Transcription|Protein Binding|Cell Nucleus 16 LRP3 23065012 Am. J. Respir. Crit. Care Med. 2012 PMC3622442 10.1164/rccm.201207-1280OC 20 1 1 44 *Chronic Obstructive Pulmonary Disease|CpG Islands|DNA Methylation|Processes, Epigenetic|Smoking|Case-Control Studies 16 LRRC10 23236519 PLoS ONE 2012 PMC3517560 10.1371/journal.pone.0051621 17 26 2 52 Mice|Humans|Animals|Child|*Cardiomyopathy, Dilated|*Leucine|Cardiomyocytes|Muscle Proteins|Actin|Cardiomegaly|Actinin|Signal Transduction Pathways|LRRC10 protein, human|Microfilament Proteins 16 NOC3L 22796266 Cancer Epidemiol 2012 10.1016/j.canep.2012.05.016 20 1 2 95 Humans|IL10 protein, human|*Interleukin-10|*Stomach Neoplasms|*Asian Continental Ancestry Group|SNPs|Genetic Predisposition to Disease|*Genes, Neoplasm|Gene Frequency|Alleles|Neoplasm Proteins|Genotype|Antigens, Neoplasm|GPI-Linked Proteins|Case-Control Studies|PSCA protein, human 16 PHACTR4 23236287 PLoS Genet. 2012 PMC3516541 10.1371/journal.pgen.1003065 59 1 7 152 Humans|Animals|*Hepatitis B virus|*Liver Cancer|Carcinoma, Hepatocellular|Caenorhabditis elegans|Hepatitis B, Chronic|*Sequencing, Next-Generation|DNA, Viral|Hepatitis B|Virus Integration|Transcriptase, Telomerase Reverse|MASP2 protein, human|Mannose-Binding Protein-Associated Serine Proteases|LRFN2 protein, human|Membrane Proteins|FOX-1 protein, C elegans|RNA-Binding Proteins|Caenorhabditis elegans Proteins 16 PHACTR4 23203801 J. 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Sci. 2012 10.1242/jcs.113241 6 8 0 152 Animals|Mice|*Actins|*Protein Phosphatase 1|*Microfilament Proteins|myocardin|Nuclear Proteins|Trans-Activators|Cell Nucleus|Protein Binding|Phosphorylation|Amino Acid Sequence|NIH 3T3 Cells|Gene Expression Regulation|Actin Depolymerizing Factors 16 PHACTR4 23076051 Cell Adh Migr 2012 PMC3496679 10.4161/cam.21266 3 2 1 152 Infant, Newborn|Humans|Mice|Animals|*Neural Crest|Enteric Nervous System|*Integrins|Cell Movement|Disease, Hirschsprung's|Cell Differentiation|Signal Transduction|Embryo, Mammalian|Nuclear Proteins|Gastrointestinal Tract|Disease Models, Animal 16 PHACTR4 22766235 Neuroscience 2012 10.1016/j.neuroscience.2012.06.059 5 0 1 152 Animals|Mice|Glial Fibrillary Acidic Protein|Brain Injury|Neurons|Gliosis|Brain|Gene Expression Regulation, Developmental|mRNA|Animals, Newborn|Embryo, Mammalian|Disease Models, Animal 16 PHACTR4 22215812 Genes Dev. 2012 PMC3258968 10.1101/gad.179283.111 28 2 1 152 Humans|Mice|Animals|*Neural Crest|*Protein Phosphatase 1|*Signal Transduction|Cell Migration|Enteric Nervous System|Disease, Hirschsprung's|Integrins|Gastrointestinal Tract|*Microfilament Proteins|Actin Depolymerizing Factors 16 PHACTR4 22215804 Genes Dev. 2012 PMC3258960 10.1101/gad.184192.111 1 1 0 152 Neural Crest Cells|*Signal Transduction|Enteric Nervous System|Cell Movement|Cell Adhesion|Integrin beta1|Focal Adhesions|Protein Phosphatase 1|Actin|Hand Strength 16 SCAPER 22890838 Int. J. Cancer 2012 10.1002/ijc.27774 13 0 2 22 *Lymphoma, B-Cell, Marginal Zone|*Clonal Evolution|Translocation, Genetic|Lymphoma, Large B-Cell, Diffuse|In Situ Hybridization, Fluorescence|Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein|Neoplasm Proteins|Small-Cell Lymphomas|Caspases|Composite Lymphoma|*Genetic Profile|*Gastrointestinal Tract|Genomics 17 SH3BGRL3 22595520 J. Cell. Sci. 2012 10.1242/jcs.101758 47 0 10 83 *Cell Differentiation|Myoblasts|Myogenesis|MicroRNAs|Cell Proliferation|3' Untranslated Regions|Gene Expression Regulation|MAP4K3 protein, human|Protein-Serine-Threonine Kinases|Cell Line|Downregulation|Muscle, Skeletal 16 STXBP5L 23223146 J. Invest. Dermatol. 2012 10.1038/jid.2012.458 4 0 0 36 Middle Aged|Humans|Female|*Genome-Wide Association Study|*Skin Aging|*European Continental Ancestry Group|Linkage Disequilibrium|SNPs|*Face|Genotypes|Lentigines|*Skin Diseases|Regressions, Linear|STXBP5L protein, human|Carrier Proteins|FBXO40 protein, human|F-Box Proteins 16 TBC1D23 22926826 Immunol. Res. 2012 PMC3921965 10.1007/s12026-012-8344-0 1 26 0 56 *Immunity, Innate|Toll-Like Receptors|Inflammation|Signal Transduction Pathways|Sepsis 16 TBC1D23 22312129 J. Immunol. 2012 PMC3293945 10.4049/jimmunol.1102595 0 41 0 56 Mice|Animals|*Immunity, Innate|*Signal Transduction|Macrophages|RNA Interference|Gene Expression Regulation|Oligonucleotide Array Sequence Analysis|Inflammation|Mice, Knockout|Blotting, Western|Caenorhabditis elegans|Transcription Factor|Tbc1d23 protein, mouse|GTPase-Activating Proteins 16 THEMIS2 22732588 J. Immunol. 2012 PMC3401357 10.4049/jimmunol.1200123 16 43 0 62 Mice|Animals|*Thymocytes|*Lymphocyte Activation|GRB2 protein, human|GRB2 Adaptor Protein|Receptors, Antigen, T-Cell|Cell Differentiation|Signal Transduction|Mice, Transgenic|B Cells|*Hematopoiesis|Mice, Inbred C57BL|Themis2 protein, mouse|Intracellular Signaling Peptides and Proteins 16 THEMIS2 22565810 J. Cell. Biochem. 2012 10.1002/jcb.24175 0 1 0 62 Female|Humans|Tamoxifen|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Cell Line, Tumor|Gene Expression Profiling|Ovarian Neoplasms|Oligonucleotide Array Sequence Analysis|Apoptosis|Intracellular Signaling Peptides and Proteins|Upregulation 16 ARL4D 21769420 Int. J. Mol. Med. 2011 10.3892/ijmm.2011.751 2 0 0 72 Mice|Animals|*Adipogenesis|3T3-L1 Cells|Adipocytes|Cell Differentiation|Adipose Tissue|ADP-Ribosylation Factor|Valproic Acid 16 ATXN8 22053702 Hiroshima J. Med. Sci. 2011 1 0 0 7 Humans|Spinocerebellar Ataxia 12|Spinocerebellar Ataxias|Spinocerebellar Ataxia 10|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Trinucleotide Repeat Expansion|Ataxins|Ataxin-7|*PCR|Trinucleotide Repeats|Ataxia, Friedreich|Tandem Repeats, Short|Nerve Tissue Proteins|Pedigree|DNA Repeat Expansion 18 BCAS4 21305644 Genes Chromosomes Cancer 2011 10.1002/gcc.20860 6 0 0 111 Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|*Specificity|Gene Expression Regulation, Neoplastic|Algorithm|Computational Biology|Cell Line, Tumor 16 c10orf11 22180457 Hum. Mol. Genet. 2011 10.1093/hmg/ddr597 22 0 1 1 Humans|*Tamoxifen|*Genome-Wide Association Study|Japan|Antineoplastic Agents, Hormonal|CYP2D6|Chemotherapy, Adjuvant|Disease-Free Survival|Genotype|Neoplasm Recurrence, Local|Alleles|*Adjuvants, Pharmaceutic|Single Nucleotide Polymorphisms|Proportional Hazards Models|*Combined Modality Therapy 16 c10orf11 21946350 Nat. Genet. 2011 PMC3267376 10.1038/ng.941 179 1 21 1 Humans|*Genome-Wide Association Study|*Follow-Up Studies|Forced Expiratory Volume|Forced Vital Capacity|Chronic Obstructive Pulmonary Disease|Respiratory Function Tests|Lung|Spirometry|Genetic Predisposition to Disease|Genetic Loci|Polymorphism, Single Nucleotide|Genome, Human|European Continental Ancestry Group|Smoking|Transforming Growth Factor beta2 16 cdkl1 21747697 Int J Mol Sci 2011 PMC3131581 10.3390/ijms12063606 7 11 2 103 Animals|Male|Female|*Zebrafish|Hedgehog Proteins|Zebrafish Proteins|Embryo, Nonmammalian|Cyclin-Dependent Protein Kinases|Amino Acid Sequence|Gene Expression Regulation, Developmental|Phosphorylation|Morphogenesis|NEUROG1 protein, human|Nerve Tissue Proteins|Protein-Serine-Threonine Kinases|Cloning, Molecular|mRNA|Testis|Basic Helix-Loop-Helix Transcription Factors 16 EFHD1 22001757 Nat. Genet. 2011 PMC3482372 10.1038/ng.970 197 1 18 78 Humans|*Genome-Wide Association Study|Genetic Association Studies|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Gene Frequency|Non-alcoholic Fatty Liver Disease|Lipase|Adaptor Proteins, Signal Transducing|Membrane Proteins|Liver|MLXIPL protein, human|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|ATP8B1 protein, human|Adenosine Triphosphatases|CD276 protein, human|B7 Antigens|ASGR1 protein, human|Asialoglycoprotein Receptor 16 EFHD1 21937081 Hum. Pathol. 2011 10.1016/j.humpath.2011.06.015 8 0 0 78 *Transcriptome|*Adenocarcinoma|Pleural Effusion, Malignant|*Lung|Lung Neoplasms|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Immunohistochemistry|Gene Expression Profiling|Hepatocyte Nuclear Factor 3-alpha|Diagnosis, Differential|Matrix Metalloproteinase 7|Lung Adenocarcinoma|Cluster Analysis 16 EFHD1 21795503 FASEB J. 2011 10.1096/fj.11-184937 11 0 2 78 Humans|Genome-Wide Association Study|*Arabs|*Schizophrenia|Genetic Linkage|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Haplotypes|Genotype|Family|Case-Control Studies|EFHD1 protein, human|Calcium-Binding Proteins 16 EFHD1 21244694 Cell Commun. 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Chem. 2011 PMC3093903 10.1074/jbc.M110.133603 0 8 1 45 Mice|Animals|HDAC1 protein, human|*Histone Deacetylase 1|YY1 Transcription Factor|Promoter Regions, Genetic|Transcription, Genetic|Repressor Proteins|Histone Deacetylases|Binding Sites|Co-Repressor Proteins|Yy1 protein, mouse 16 KIAA1279 21712996 PLoS ONE 2011 PMC3119685 10.1371/journal.pone.0021219 27 3 0 164 Humans|*Hirschsprung Disease|*DNA Copy Number Variations|Pilot Projects|*Modifier Gene|Transcription Factors|Proto-Oncogene Proteins c-ret|SOXE Transcription Factors|Alleles|Mutations|Receptor, Endothelin B|Phenotype|KIAA1279 protein, human|Nerve Tissue Proteins 16 KIAA1462 21884682 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.08.073 13 2 1 64 Animals|Mice|*Coronary Artery Disease|Endothelial Cells|*Intercellular Junctions|cadherin 5|Cadherins|Antigens, CD|Cell Adhesion|Cell Adhesion Molecules|Cultured Cells|Endothelium, Vascular|Neovascularization, Physiologic|Cells, Epithelial 17 KIAA1462 21378988 Nat. Genet. 2011 10.1038/ng.782 257 0 22 64 Humans|*Genome-Wide Association Study|*Coronary Artery Disease|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Quantitative Trait Loci|Case-Control Studies|European Continental Ancestry Group|Risk Factors 17 LRRC10 21345312 BMB Rep 2011 10.5483/BMBRep.2011.44.2.123 2 2 1 52 Mice|Animals|*Promoter Regions, Genetic|Regulatory Sequences, Nucleic Acid|Transcription Factors|DNA-Binding Proteins|*Heart|Binding Sites|Base Sequence|Reporter Gene|GATA4 Transcription Factor|Gene Expression Regulation, Developmental|Cloning, Molecular 16 MLIP 21498514 J. Biol. Chem. 2011 PMC3103349 10.1074/jbc.M110.165548 9 1 0 72 Humans|Animals|*Lamin Type A|Emery-Dreifuss Muscular Dystrophy|Nuclear Envelope|*Muscle Proteins|Limb Girdle Muscular Dystrophy|Nuclear Proteins|Cardiomyopathy, Dilated|Cell Nucleus|Mutations|Splicings, Alternative|*Muscle|Heart|Phenotypes 16 NOC3L 21482774 Proc. Natl. Acad. Sci. U.S.A. 2011 PMC3286962 10.1073/pnas.1018872108 57 11 2 95 Humans|*Tamoxifen|Antineoplastic Agents, Hormonal|RNA Interference|shRNA|Drug Resistance, Neoplasm|Estrogen Receptor alpha|MCF-7 Cells|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction|Estrogens|Apoptosis|ING5 protein, human|Transcription Factors|Tumor Suppressor Proteins|BAP1 protein, human|Ubiquitin Thiolesterase 16 STXBP5L 21998599 PLoS Genet. 2011 PMC3188574 10.1371/journal.pgen.1002323 34 21 1 36 Mice|Animals|*Insulin Secretion|*Diabetes Mellitus, Type 2|*Quantitative Trait Loci|*Mice, Inbred C57BL|Pancreatic Islets|Insulin|Glucose|Syntaxin-1A|Mice, Congenic|R-SNARE Proteins|Fasting|Mice, Inbred Strains|Syntaxin 4|Cloning, Molecular|tomosyn protein, mouse|Nerve Tissue Proteins|STXBP5L protein, mouse 16 THEMIS2 21455565 Int. J. Mol. Med. 2011 10.3892/ijmm.2011.663 1 5 0 62 Humans|Female|*Vitamin D3|*Tretinoin|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Receptors, Estrogen|siRNA|Cell Line, Tumor|CDH1 protein, human|E Cadherin|RNA Interference|Up-Regulation|Ovarian Neoplasms|Intracellular Signaling Peptides and Proteins|Cell Proliferation|Cell Differentiation|Antigens, CD 16 TTC39B 21738485 PLoS Genet. 2011 PMC3128106 10.1371/journal.pgen.1002138 85 3 5 84 Adult|Humans|Genome-Wide Association Study|High Density Lipoprotein Cholesterol|Low Density Lipoprotein Cholesterol|SNPs|Frequencies, Allele|European Continental Ancestry Group|Linkage Disequilibrium|Triglycerides|Asian|*Lipids|*Complement Factor B|Genotype|Hispanic|African Americans|Mexican Americans|Genomics|*Epidemiological Study|Hawaii 16 UBR3 21933813 Nucleic Acids Res. 2011 PMC3258136 10.1093/nar/gkr744 29 9 3 148 Humans|Mice|Animals|APEX1 protein, human|*DNA-(Apurinic or Apyrimidinic Site) Lyase|DNA Repair|*Stability, Genome|UBB protein, human|*Ubiquitin|DNA Damage|Ubiquitylation|Lysine|Protein Binding|Acetylation|E3 Ubiquitin Ligase|UBR3 protein, mouse 16 ARL4D 21124846 PLoS ONE 2010 PMC2991347 10.1371/journal.pone.0015008 13 4 1 72 Rats|Animals|*Neuroprotection|Neurodegenerative Diseases|N Methyl D aspartate|Excitatory Amino Acid Agonists|Neurons|Glutamic Acid|Receptors, N-Methyl-D-Aspartate|Neuroprotective Agents|Excitatory Amino Acid Antagonists|Glucose|Cerebral Cortex|Cell Survival|Cells, Cultured|Apoptosis|Oxygen|Rats, Sprague-Dawley 16 ARL4D 20858711 Physiol. Genomics 2010 PMC3008368 10.1152/physiolgenomics.00044.2010 2 0 0 72 Mice|Animals|*Cholesterol, HDL|*C57BL Mice|*Mice, Inbred DBA|*Epistasis, Genetic|Crosses, Genetic|Chromosome Mapping|Quantitative Trait Loci|Species Specificity 16 ARL4D 20161818 Mol. Vis. 2010 PMC2822553 15 9 0 72 *RNA Polymerase II|*Transcriptional Activation|Transcription Start Sites|Retinal Rod Photoreceptor Cells|Homeodomain Proteins|Eye Proteins|Trans-Activators|Promoter Regions, Genetic|*Neurogenesis|RNA 16 ATXN8 20403608 J. Neurol. Sci. 2010 10.1016/j.jns.2010.03.006 2 0 0 7 Female|Humans|Adult|HTT protein, human|*Huntingtin Protein|Trinucleotide Repeat Expansion|Huntington Disease|Nerve Tissue Proteins|Nuclear Proteins|Parkinsonian Disorders|Tremor, Intention|*Syndrome|Disease Progression|RNA, Long Noncoding|Nucleus Caudatus 18 BCAS4 20682712 Clin. Cancer Res. 2010 PMC3805460 10.1158/1078-0432.CCR-10-0066 16 15 0 111 saracatinib|*In Situ Hybridization, Fluorescence|*Quinazolines|*Benzodioxoles|*Colorectal Cancer|Xenograft Model Antitumor Assays|src-Family Kinases|Drug Resistance, Neoplasm|Antineoplastic Agents|Protein Kinase Inhibitors|Cell Line, Tumor|Cell Proliferation|Biomarkers, Tumor|*Colonic Neoplasms|Signal Transduction 16 EPPK1 20151282 Jpn. J. Ophthalmol. 2010 10.1007/s10384-009-0751-y 1 0 0 76 Mice|Animals|Retina|Retinal Ganglion Cells|Neuroglia|RNA, Messenger 16 Gon4l 20530203 J. Exp. 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Biol. 2010 PMC2849474 10.1128/MCB.01350-09 35 4 4 123 Humans|*Phosphorylation|RNA Recognition Motif Proteins|DNA Helicases|Poly-ADP-Ribose Binding Proteins|RNA Helicases|EIF-2alpha|OGFOD1 protein, human|Carrier Proteins|Cytoplasmic Granules|eIF-2alpha Kinase|Polyribosomes|Ribosome|Protein Biosynthesis|arsenite|Arsenites|Ubiquitin Thiolesterase|Nuclear Proteins|USP10 protein, human 16 ogfod1 20124481 Cancer Res. 2010 PMC2852266 10.1158/0008-5472.CAN-09-3143 17 0 1 123 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|Leukocytes, Mononuclear|B Cells|Graft Versus Host Disease|Lymphocyte Transfusion|Transplantation, Homologous|Bone Marrow Transplantation|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|*Biomarkers|OGFOD1 protein, human|Carrier Proteins|Nuclear Proteins|DAPK3 protein, human|Death-Associated Protein Kinases 16 PHACTR4 20824714 Int. J. Cancer 2010 10.1002/ijc.25641 9 0 0 152 *Microsatellite Instability|*Nonsense Mediated mRNA Decay|Mutations, Frameshift|*Mutation|Termination Codon, Premature|Colorectal Neoplasms|DNA Mutational Analysis|Microsatellite Repeats|DNA, Neoplasm|mRNA|DNA Microarrays|Cell Transformation, Neoplastic|Transcription, Genetic 16 PHF23 20219246 Leuk. Res. 2010 10.1016/j.leukres.2010.02.015 4 1 0 40 nuclear pore complex protein 98|*PHD Zinc Fingers|Nuclear Pore Complex Proteins|*Cell Differentiation|Chromosomal Translocations|Oncogene Proteins, Fusion|Leukemia, Myeloid, Acute|Homeodomain Proteins|Transcription Factors|Amino Acid Sequence 16 RCBTB1 21151023 Leukemia 2010 10.1038/leu.2010.288 32 0 5 75 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|13q deletion syndrome|*Chromosomes, Human, Pair 13|*Chromosome Deletion|*Chromosome Disorders|*Disease Progression|Chromosome Aberrations|DNA Copy Number Variations|In Situ Hybridization, Fluorescence|Prognosis|ZAP70 protein, human|ZAP-70 Protein-Tyrosine Kinase|Genomics|RCBTB1 protein, human|Guanine Nucleotide Exchange Factors 16 RCBTB1 20926398 Cancer Res. 2010 PMC2982930 10.1158/0008-5472.CAN-10-1960 9 23 1 75 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Apoptosis|*DNA Repair|Viability, Cell|Cell Proliferation|Tumor Suppressor Proteins|Cell Cycle|Cell Line, Tumor|DNA Damage|Gene Expression Regulation, Neoplastic|Signal Transduction|Genes, Tumor Suppressor|*Chromosome Structures 16 RCBTB1 20085599 Clin. Exp. Allergy 2010 10.1111/j.1365-2222.2009.03364.x 23 1 0 75 *Allergy|*Asthma|*Respiratory Sounds|Interleukin-4 Receptor alpha Subunit|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Interleukin-13|Gene Frequency|Immunoglobulin E|Genotype|Case-Control Studies 16 TBC1D23 20824714 Int. J. Cancer 2010 10.1002/ijc.25641 9 0 0 56 *Microsatellite Instability|*Nonsense Mediated mRNA Decay|Mutations, Frameshift|*Mutation|Termination Codon, Premature|Colorectal Neoplasms|DNA Mutational Analysis|Microsatellite Repeats|DNA, Neoplasm|mRNA|DNA Microarrays|Cell Transformation, Neoplastic|Transcription, Genetic 16 TBC1D23 20377877 BMC Microbiol. 2010 PMC2858032 10.1186/1471-2180-10-103 6 16 0 56 Humans|Animals|Rats|*Macrophages, Alveolar|*Rats, Sprague-Dawley|Pneumocystis carini|Pneumocystis Pneumonia|Pneumocystis|Phagocytosis|Bronchoalveolar Lavage Fluid|*Gene Expression 16 THEMIS2 20644716 PLoS ONE 2010 PMC2903609 10.1371/journal.pone.0011465 12 51 1 62 *Toll-Like Receptor|*Macrophage|*Signal Transduction|NF-kappa B|Cytokines|Lipopolysaccharides|Tumor Necrosis Factor-alpha|Phosphorylation|Intracellular Signaling Peptides and Proteins 16 THEMIS2 20569072 Cancer Invest. 2010 10.3109/07357907.2010.483511 0 0 0 62 Female|Humans|ERBB2 protein, human|*Receptor, ErbB-2|Endometrial Cancer|Endometrium|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Adenocarcinoma|RNA, Messenger|Cell Line, Tumor|*Gene Expression 16 TTC39B 20686565 Nature 2010 PMC3039276 10.1038/nature09270 1458 9 102 84 Humans|Animals|Mice|High Density Lipoprotein Cholesterol|Low Density Lipoprotein Cholesterol|Triglycerides|*Lipids|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Asians|European Continental Ancestry Group|African Continental Ancestry Group|Coronary Artery Disease|Genetic Loci|Genetic Predisposition to Disease|Genotype|African Americans|Phenotypes|Genetic Variation|TTC39B protein, mouse|Lipoproteins, HDL 16 UNCX 20692344 Mol. Cell. Neurosci. 2010 PMC2962766 10.1016/j.mcn.2010.07.013 11 8 1 15 Mice|Animals|*Olfactory Epithelium|Sensory Neurons, Olfactory|*Neural Stem Cells|NEUROG1 protein, human|Basic Helix-Loop-Helix Transcription Factors|Olfactory Bulb|*Cell Death|Cell Differentiation|Neurogenesis|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|UMODL1 protein, human|Membrane Proteins|mRNA|*Cell Survival|Calcium-Binding Proteins|Cell Proliferation 16 VPS13D 20686178 Sci Transl Med 2010 10.1126/scitranslmed.3001065 65 2 3 60 18 ARL4D 19327349 Exp. Cell Res. 2009 10.1016/j.yexcr.2009.03.012 9 3 0 72 cytohesin-2|*Valproic Acid|*GTPase-Activating Proteins|ADP-ribosylation factor 6|*ADP-Ribosylation Factors|*Neurite Outgrowth|Neurites|Guanine Nucleotide Exchange Factor|Signal Transduction|Neurogenesis|Cell Line|siRNA|Upregulation 16 ATXN8 19680539 PLoS Genet. 2009 PMC2719092 10.1371/journal.pgen.1000600 126 26 8 7 Animals|Mice|*Gain of Function Mutation|Spinocerebellar Ataxias|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Trinucleotide Repeat Expansion|RNA, Untranslated|Nerve Tissue Proteins|polyglutamine|Peptides|RNA, Long Noncoding|Genes, Dominant|Gene Expression|Brain|Neurons 18 ATXN8 19229559 Hum. Genet. 2009 10.1007/s00439-009-0641-x 2 5 0 7 Humans|*Alleles|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Nerve Tissue Proteins|RNA, Untranslated|Parkinson Disease|RNA, Long Noncoding|*Disorders, Neurological|Alzheimer Disease|Promoter Regions, Genetic|Asian Continental Ancestry Group 18 ATXN8 19203395 BMC Mol. Biol. 2009 PMC2647542 10.1186/1471-2199-10-9 13 9 1 7 *Histone Code|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Trinucleotide Repeat Expansion|Spinocerebellar Ataxias|RNA, Untranslated|Nerve Tissue Proteins|RNA, Long Noncoding|polyglutamine|Peptides|*Protein Processing, Post-Translational 18 c10orf11 19844253 Eur. J. Hum. Genet. 2009 PMC2987210 10.1038/ejhg.2009.163 7 0 1 1 Humans|Comparative Genomic Hybridization|*Chromosome Aberrations|*Translocation, Genetic|Chromosome Banding|Chromosome Deletion|Intellectual Disability|In Situ Hybridization, Fluorescence|Abnormalities, Multiple|Chromosome Disorders|Hypotonia|*Chromosome Structures 16 EPPK1 19322062 J. Pediatr. Gastroenterol. Nutr. 2009 10.1097/MPG.0b013e3181846aab 0 0 0 76 Humans|Mice|Animals|Trichohepatoenteric Syndrome|*Facies|*Diarrhea, Infantile|*Hair Diseases|*Fetal Growth Retardation|Abnormalities, Multiple|CTNNB1 protein, human|*beta Catenin|DNA Mutational Analysis|Phenotypes|Intellectual Disability|Syndrome|Genotype|ErbB Receptors|JUP protein, human|gamma Catenin|HRAS protein, human|Proto-Oncogene Proteins p21(ras) 16 Gon4l 19656853 Mol. Biol. Cell 2009 PMC2754932 10.1091/mbc.E09-02-0109 7 3 1 45 Animals|Zebrafish Proteins|Zebrafish|Embryo, Nonmammalian|Apoptosis|Protein-Serine-Threonine Kinases|Cell Cycle Proteins|Cell Cycle|Tumor Suppressor Protein p53|DNA Damage|*Cell Cycle Checkpoints|Animals, Genetically Modified|Gene Expression Regulation, Developmental|Cell Differentiation|Gene Knockdown Techniques|DNA Replication|Mutation|Udu protein, zebrafish 16 INIP 19683501 Mol. Cell 2009 PMC2756616 10.1016/j.molcel.2009.06.011 63 16 5 79 Humans|*Genomic Stability|DNA Repair|DNA, Single-Stranded|DNA Replication|DNA Damage|DNA-Binding Proteins|Protein Binding|Mitochondrial Proteins|Recombination, Genetic|Ionizing Radiation|DNA 16 INIP 19605351 J. Biol. Chem. 2009 PMC2749126 10.1074/jbc.C109.039586 48 20 2 79 Humans|SSBP1 protein, human|DNA-Binding Proteins|DNA Repair|Mitochondrial Proteins|DNA Damage|DNA Breaks, Double-Stranded|Ataxia Telangiectasia Mutated Proteins|Phosphorylation|*Multiprotein Complexes|DNA|Signal Transduction|Ataxia-Telangiectasia 16 INIP 20391411 Vet. Ital. 2009 0 0 0 79 Humans|Child|Male|Animals|Cattle|United States|Horses|*Rabies|Rabies Vaccine|*Vaccination|Animals, Wild|Nazi|Public Health|Academies and Institutes|Europe|*Father|Mexico|New York|New Mexico|London|England 16 INIP 19439318 J Commun Disord 2009 PMC2892123 10.1016/j.jcomdis.2009.03.008 17 0 2 79 Infant|Humans|*Speech|*Linguistic|Lip|Movement|Biomechanical Phenomena|Jaw|Communication|Cognition 16 KIAA1279 19536565 Hum. Genet. 2009 10.1007/s00439-009-0702-1 16 0 1 164 *Epilepsies|Malformations of Cortical Development|Periventricular Nodular Heterotopia|Lissencephaly|Subcortical Band Heterotopia|Cerebral Cortex|*Neurogenesis|Febrile Seizures 16 KIAA1279 19120042 Acta Paediatr. 2009 10.1111/j.1651-2227.2008.01160.x 28 0 0 164 Humans|Child|*Neuronal Migration Disorders|Perisylvian syndrome|Malformations of Cortical Development|Epilepsy|Lissencephaly|Periventricular Nodular Heterotopia|FLNA protein, human|Filamin A|Brain|Mutations|Miller Dieker Syndrome|Cerebral Cortex|Magnetic Resonance Imaging|Abnormalities, Multiple|Neurons|Cerebral Ventricles|Cell Movement|Genes, Regulator 16 KIAA1462 19763160 PLoS Genet. 2009 PMC2730532 10.1371/journal.pgen.1000648 75 0 7 64 Male|Female|Humans|Meiosis|*Genetic Testing|*Homologous Recombination|Phenotype|Pedigree|Genome-Wide Association Study|Genetic Variation|Genotypes|Genetic Loci|Polymorphism, Single Nucleotide|Iceland|RNF212 protein, human|Ligases 17 LRP3 19497050 Traffic 2009 10.1111/j.1600-0854.2009.00933.x 8 2 0 44 *Nucleobindins|*Endosomes|trans Golgi Network|GGA adaptor proteins|Adaptor Proteins, Vesicular Transport|Protein Sorting|Golgi Apparatus|Binding Protein|LDLR protein, human|*Receptors, LDL|Vesicular Transport Proteins|Membrane Glycoproteins|ADP-Ribosylation Factors|Protein Structure, Tertiary|Nerve Tissue Proteins|Membrane Proteins|Lysosomes|Protein Binding 16 mex3b 19542354 Development 2009 10.1242/dev.029165 8 0 0 72 Animals|*Xenopus laevis|*mRNA|*RNA Binding Protein|Xenopus Proteins|Body Patterning|Neural Plate|Gene Expression Regulation, Developmental|Base Sequence|Amino Acid Sequence|Embryo, Nonmammalian|3' UTR|Fibroblast Growth Factors|Signal Transduction 16 NOC3L 19801824 Biol. Pharm. Bull. 2009 10.1248/bpb.32.1656 5 1 1 95 Mice|Animals|*Hyperplasia|*Adipose Tissue|Adipogenesis|Adipocytes|3T3-L1 Cells|Nuclear Proteins|Basic-Leucine Zipper Transcription Factors|Cell Cycle Proteins|DNA Replication|Mice, Transgenic|Glucose|Cell Differentiation|Promoter Regions, Genetic|Body Weight|Obesity 16 PHF23 19430464 Nature 2009 PMC2697266 10.1038/nature08036 157 18 11 40 Humans|Mice|Animals|*PHD Zinc Fingers|histone H3 trimethyl Lys4|Histones|Chromatin|Methylation|nuclear pore complex protein 98|Nuclear Pore Complex Proteins|Homeodomain Proteins|Transcription Factors|Lysine|Tumor Suppressor Proteins|*Malignancies, Hematopoietic|Acetylation|Protein Binding|Cell Transformation, Neoplastic|Mutations 16 PKD1L2 19578180 Hum. Mol. Genet. 2009 PMC2742400 10.1093/hmg/ddp304 7 3 1 9 Mice|Animals|*Up-Regulation|*Neuromuscular Diseases|Mice, Transgenic|Muscle, Skeletal|PKD1L2 protein, human|*Receptors, G-Protein-Coupled|Muscle Atrophy|Neuromuscular Junction|*Genes, Regulator|*Transcriptional Activation|Muscle Fibers, Skeletal|Disease Models, Animal 16 RCBTB1 19256485 Biochemistry 2009 PMC2680606 10.1021/bi801971m 12 33 1 75 *Ubiquitin-Conjugating Enzymes|*E3 Ligase|*Cullin Proteins|RBX1 protein, human|Carrier Proteins|Ubiquitin|Protein Binding|Amino Acid Sequence 16 SCAPER 19412524 PLoS Genet. 2009 PMC2669883 10.1371/journal.pgen.1000464 31 1 2 22 Humans|Genome-Wide Association Study|*Bayes Theorem|*Case-Control Studies|Epistasis, Genetic|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Models, Genetic|Computational Biology|Algorithms|Genotype|Age Related Macular Degeneration|Computer Simulation|Genome 17 STXBP5L 19586676 J. Hepatol. 2009 PMC2883297 10.1016/j.jhep.2009.04.027 23 0 0 36 Humans|*Hepatitis C, Chronic|*Toll-Like Receptor 4|*Fibrosis, Liver|*Hepatitis C|Single Nucleotide Polymorphisms|*European Continental Ancestry Group|Genetic Predisposition to Disease|Haplotypes|Genotype|Linkage Disequilibrium|Disease Progression|Case-Control Studies 16 THEMIS2 19942713 Endocr. Relat. Cancer 2009 10.1677/ERC-09-0095 1 4 0 62 Humans|Female|estrogen receptor alpha, human|Estrogen Receptor alpha|*Estrogens|ERbeta|Tamoxifen|Oestradiol|progesterone receptor B|Progesterone Receptor|Antineoplastic Agents, Hormonal|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cellular Proliferation|Neoplasm Proteins|Ovarian Cancer|Drug Resistance, Neoplasm|shRNA|MCF 7 Cells|Upregulation 16 THEMIS2 19308812 Cancer Invest. 2009 10.1080/07357900802620877 2 0 0 62 Female|Humans|*Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotypes|Gene Frequency|Homozygote|Allele|Case-Control Studies|Heterozygote|Odds Ratio|Phenotype|Risk Factors 16 UNCX 19520072 Dev. Biol. 2009 PMC2898144 10.1016/j.ydbio.2009.06.006 10 4 0 15 Mice|Animals|*Homeodomain Proteins|Somite|*Mesoderm|Body Patterning|Paired Box Transcription Factors|Gene Expression Regulation, Developmental|*Bone and Bones|In Situ Hybridization|Spine|Phenotype|Tbx18 protein, mouse|T-Box Domain Proteins|Meox1 protein, mouse 16 UNCX 19268448 Dev. Biol. 2009 PMC2697309 10.1016/j.ydbio.2009.02.023 16 14 0 15 Humans|Mice|Animals|Somites|*Embryonic Development|Mesoderm|Intracellular Signaling Peptides and Proteins|NRARP protein, human|*Neoplasm Proteins|Membrane Proteins|Body Patterning|Receptors, Notch|Signal Transduction|Gene Expression Regulation, Developmental|AXIN2 protein, human|Axin Protein|Mutation|In Situ Hybridization|DLL3 protein, human|Lfng protein, mouse|Glycosyltransferases 16 ARL4D 18301726 Neural Plast. 2008 PMC2248427 10.1155/2007/26496 34 6 3 72 *Fluoxetine|*Long-Term Potentiation|*Brain-Derived Neurotrophic Factor|*Up-Regulation|*Transcriptional Activation|Antidepressant Drugs|Hippocampus|Dentate Gyrus|*Brain|Nerve Tissue Proteins|Synaptic Transmission|Neuronal Plasticity|Signal Transduction|RNA, Messenger|Cortex, Prefrontal 16 ATXN8 18418692 Cerebellum 2008 10.1007/s12311-008-0010-7 28 0 1 7 Humans|Mice|Animals|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Spinocerebellar Ataxias|Trinucleotide Repeat Expansion|Nerve Tissue Proteins|RNA, Untranslated|Penetrance|Phenotype|*Mutation|RNA, Long Noncoding|Pedigree|Intranuclear Inclusions|Microsatellite|polyglutamine|Peptides 18 c10orf11 18336583 Dev. Growth Differ. 2008 10.1111/j.1440-169X.2008.01012.x 4 0 0 1 Animals|Humans|*Ciona intestinalis|*Wnt Signaling Pathway|CTNNB1 protein, human|beta Catenin|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Transcription Factors|Cell Differentiation|In Situ Hybridization|Vertebrates|Gene Expression Profiling|PGAP1 protein, human|Membrane Proteins|Phosphoric Monoester Hydrolases 16 EFHD1 18163890 Biol. Chem. 2008 10.1515/BC.2008.011 18 2 1 78 Humans|*Downregulation|*Hepatocyte Nuclear Factor 4-alpha|HEK293 Cells|*Cell Proliferation|Renal Cell Carcinoma|Cancer, Kidney|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|RNA Interference|*Epithelial Cells|*Kidney|Gene Expression Profiling|Cell Line, Tumor|Genes, cdc|ANK3 protein, human|Ankyrins|EFHD1 protein, human|Calcium-Binding Proteins 16 EPPK1 18498355 Genes Cells 2008 10.1111/j.1365-2443.2008.01196.x 13 0 0 76 Mice|Animals|Acute Disease|Acute Pancreatitis|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|Carcinoma in Situ|*Regeneration|Cerulein|pancreatic and duodenal homeobox 1 protein|Trans-Activators|Cell Transformation, Neoplastic|Biomarkers, Tumor|Progenitor Cells|Homeodomain Proteins 16 FOXS1 18288644 Mol. Reprod. Dev. 2008 10.1002/mrd.20888 7 2 0 119 Male|Female|Mice|Animals|*Testis|Endothelial Cells|Phylogeny|Forkhead Transcription Factors|Gene Expression Regulation, Developmental|Neovascularization, Physiologic 16 HMGB4 18987332 Biol. Reprod. 2008 10.1095/biolreprod.108.070243 17 0 1 26 Mice|Male|Animals|*Spermatids|*Testis|Spermatogenesis|Spermatocytes|Cell Nucleus|Chromatin|Amino Acid Sequence|Nuclear Proteins|Transcription Factors|Haploid|Euchromatin|Cloning, Molecular|Transfection|RNA, Messenger|HMGB Proteins|HMGB4 protein, mouse 16 KIAA1279 18332248 Arch. Neurol. 2008 10.1001/archneur.65.3.358 7 0 0 164 Child|Humans|*Brain|Malformations of Cortical Development|Epilepsy|Magnetic Resonance Imaging|Cerebral Cortex|*Radiologists 16 KIAA1279 18192286 Development 2008 10.1242/dev.012377 34 0 3 164 Animals|Humans|*Zebrafish|Goldberg-Shprintzen megacolon syndrome|*Axons|*Hirschsprung Disease|*Craniofacial Abnormalities|Zebrafish Proteins|Microtubules|Kinesin|Neurogenesis|Systems, Central Nervous|KIAA1279 protein, human|Nerve Tissue Proteins|Kif1-binding protein, zebrafish 16 LRCH1 18817323 Dev Biol (Basel) 2008 10.1159/000317180 1 0 0 44 Humans|Swine|Animals|Female|*Single Nucleotide Polymorphism|*Phenotype|Genome-Wide Association Study|Quantitative Trait Loci|Genotype|Reproduction 16 LRRC10 18781631 Genesis 2008 10.1002/dvg.20422 5 0 1 52 Mice|Animals|Myocardium|Muscle Proteins|Myocytes, Cardiac|Zebrafish|Amino Acid Sequence|Mice, Knockout|Gene Expression Regulation, Developmental|Phenotype 16 mex3b 18779327 J. Biol. Chem. 2008 10.1074/jbc.M802927200 19 0 3 72 Humans|Animals|*RNA Binding Protein|Argonaute Proteins|*Protein Transport|Cytoplasmic Granules|mRNA|RNA|*Cell Movement|Caenorhabditis elegans|Cytosol 16 MLIP 18541055 BMC Bioinformatics 2008 PMC2423443 10.1186/1471-2105-9-S6-S2 2 0 0 72 Humans|*Genetic Linkage Analysis|Chromosome Mapping|*Probability|Linkage Disequilibrium|Software|Models, Genetic|Pedigree|*Computers|Algorithms|Models, Statistical|Computer Simulation 16 NOC3L 19097072 Dev. Dyn. 2008 PMC2843540 10.1002/dvdy.21821 0 3 1 95 Animals|*Zebrafish|Adipogenesis|*Mutation|Nuclear Proteins|Basic-Leucine Zipper Transcription Factors|Cell Differentiation|Cell Cycle Proteins|DNA Replication|Homozygote|*Muscular Atrophy|Muscle Fibers, Skeletal|Leukocytes 16 NOC3L 18520036 Biol. Pharm. Bull. 2008 10.1248/bpb.31.1092 5 1 0 95 Mice|Animals|*Adipogenesis|3T3-L1|*Cell Division|Basic-Leucine Zipper Transcription Factors|Cell Cycle Proteins|Adipocytes|Nuclear Proteins|DNA Replication|Cell Differentiation|Myoblasts|Cell Nucleus|RNA Interference 16 NOC3L 18284919 Biochem. Biophys. Res. Commun. 2008 10.1016/j.bbrc.2008.02.036 3 5 0 95 Mice|Animals|*Adipogenesis|*NF-kappa B|*DNA Replication|RELA protein, human|*Transcription Factor RelA|3T3-L1 Cells|Basic-Leucine Zipper Transcription Factors|Nuclear Proteins|Adipocytes|Cell Cycle Proteins|Gene Expression Regulation|Cell Differentiation|Gene Expression|Promoter Regions, Genetic 16 SCAPER 18245951 Cell Cycle 2008 10.4161/cc.7.6.5611 5 0 0 22 *Cyclin A|CDK2 protein, human|*Cyclin-Dependent Kinase 2|Cell Cycle|Cyclin-Dependent Kinases|Cyclin|Mitosis|Cell Cycle Proteins|Cell Nucleus|Phosphorylation|Cytoplasm 17 THEMIS2 18206364 J. Steroid Biochem. Mol. Biol. 2008 10.1016/j.jsbmb.2007.12.007 3 0 1 62 Humans|Female|*MCF-7 Cells|Ovarian Cancer|Apoptosis|Cell Line, Tumor|estrogen receptor alpha, human|ERalpha|ICI 182,780|*Estrogens|17 beta-Oestradiol|Antiestrogen|Estrogen Receptor beta|Gene Expression Regulation, Neoplastic|Estrogen Antagonists|Neoplasm Proteins|Upregulation|RNA, Small Interfering|RNA, Messenger|Promoter Regions, Genetic 16 TTC39B 19060906 Nat. Genet. 2008 PMC2881676 10.1038/ng.291 550 7 25 84 Humans|Genome-Wide Association Study|High Density Lipoprotein Cholesterol|*Dyslipidemia|LDL Cholesterol|Triglycerides|*Multifactorial Inheritance|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Alleles|Hypertriglyceridemia|Phenotype|Cholesterol|Genome, Human|Case-Control Studies|TIMD4 protein, human|Membrane Proteins 16 UBR3 19008229 J. Biol. Chem. 2008 PMC2615520 10.1074/jbc.M803641200 41 1 3 148 Ubiquitin Ligase E3|Substrate Specificity|Protein Binding|Protein Structure, Tertiary|Amino Acid Sequence|Zinc Fingers|*Protein Domains|recognins|Neoplasm Proteins|Peptides 16 UBR3 18985243 Dalton Trans 2008 10.1039/b809184f 0 1 0 148 *Oxidants|Crystallography, Xray|Molecular Structure|Ligands|Organometallic Compounds|Models, Molecular 16 UNCX 18797923 Dev. Genes Evol. 2008 10.1007/s00427-008-0245-9 29 0 1 15 Humans|Animals|*Genes, Homeobox|*Lancelets|Phylogeny|*Genome|Gene Duplication|Vertebrates|Evolution, Molecular|Amino Acid Sequence|Sequence Homology, Amino Acid|Transcription Factors|Embryonic Development|*Survey 16 ARL4D 17804820 Mol. Biol. Cell 2007 PMC2043562 10.1091/mbc.e07-02-0149 36 11 1 72 Humans|cytohesin-2|*Actins|Phosphatidylinositol 3-Kinases|*GTPase-Activating Proteins|ADP-Ribosylation Factor|Guanine Nucleotide Exchange Factor|ADP-Ribosylation Factor 1|Plasma Membrane|HeLa Cells|Cell Migration 16 ARL4D 17398095 Curr. Biol. 2007 10.1016/j.cub.2007.03.007 47 2 4 72 *Small G-Proteins|ADP-ribosylation factor 6|*ADP-Ribosylation Factors|cytohesin-1|*Guanine Nucleotide Exchange Factors|cytohesin-2|GTPase-Activating Proteins|*Plasma Membrane|Phosphoinositides|Phosphatidylinositol Phosphates|Signal Transduction Pathway|Protein Binding|Protein Structure, Tertiary|Endocytosis|Amino Acid Sequence|Transfection|Actin|Cell Adhesion 16 BCAS4 17668415 J. Pathol. 2007 10.1002/path.2217 37 0 2 111 Humans|Female|*Comparative Genomic Hybridization|*Fallopian Tubes|*B-DNA|*Multiplex Polymerase Chain Reaction|*DNA Fingerprinting|*Fallopian Tube Neoplasms|Cystadenocarcinoma, Serous|Ovarian Neoplasms|CCNE1 protein, human|Cyclin E|*Ovary|Oligonucleotide Array Sequence Analysis|Gene Amplification|Oncogene Proteins|ERBB2 protein, human|Receptor, ErbB-2|Gene Expression Profiling|Gene Expression Regulation, Neoplastic 16 BCAS4 17623483 Hum. Mutat. 2007 10.1002/humu.9502 9 0 1 111 Humans|Child|*Duane Retraction Syndrome|*Phenotype|*Chromosome 2|Abnormalities, Multiple|Pedigree|Mutation|Exon|Mental Retardation|*Chromosome Structures|Transcription Factors|SALL4 protein, human|ADNP protein, human|Nerve Tissue Proteins|Homeodomain Proteins 16 BCAS4 17568001 Genome Res. 2007 PMC1891342 10.1101/gr.6018607 43 0 1 111 Humans|*Transcriptome Analysis|Genome, Human|Chromosome Mapping|Sequence Analysis, DNA|Genomics|Translocation, Genetic|Transcription, Genetic|DNA 16 FOXS1 17309606 Differentiation 2007 10.1111/j.1432-0436.2006.00154.x 16 0 0 119 Neural Crest|Transcription Factor|SOXE Transcription Factors|DNA-Binding Proteins|High Mobility Group Proteins|Neurons|Gene Expression Regulation, Developmental|Neuroglia|Ganglia|Ectoderm|Dorsal Root Ganglion|Cell Differentiation|In Situ Hybridization|Cell Movement 16 Gon4l 18047649 BMC Mol. Biol. 2007 PMC2231382 10.1186/1471-2199-8-109 0 1 1 45 *Transposable Elements|*Exons|Introns|*Genes, Duplicate|RNA Splice Sites|Alu Elements 16 Gon4l 17369489 Blood 2007 10.1182/blood-2006-11-059204 12 2 1 45 Animals|*Zebrafish|Erythroid-Specific DNA-Binding Factors|Zebrafish Proteins|*Cell Differentiation|*Cell, Erythroid|Hematopoiesis|Embryo, Nonmammalian|Transcription Factors|GATA1 Transcription Factor|Gene Expression Regulation, Developmental|*Cell Nucleus|*Stem Cells|Erythroid Precursor Cells|In Situ Hybridization|Mutation|Udu protein, zebrafish 16 grwd1 18162579 Mol. Biol. Cell 2007 PMC2262995 10.1091/mbc.e07-09-0859 28 1 0 169 Animals|Humans|*Proteomics|CDT1 protein, human|*Cell Cycle Proteins|Anaphase-Promoting Complex-Cyclosome|Cdc20 Proteins|Ubiquitin-Protein Ligases|Ubiquitination|S-Phase Kinase-Associated Proteins|G1 Phase|Ubiquitin|Protein Binding|Protein Processing, Post-Translational|Cell Cycle|DNA Replication|GRWD1 protein, human|Carrier Proteins 16 LRCH1 18049793 J. Hum. Genet. 2007 10.1007/s10038-007-0216-4 6 0 1 44 Humans|*Polymorphism, Single Nucleotide|*Osteoarthritis, Knee|Frequencies, Allele|Asian|Genetic Predisposition to Disease|Genotype|Case-Control Studies|European Continental Ancestry Group 16 LRCH1 17762607 Curr Opin Rheumatol 2007 10.1097/BOR.0b013e32825b079d 16 1 0 44 *Osteoarthritis|Genetic Predisposition to Disease|Growth Differentiation Factor 5|Polymorphism, Single Nucleotide|Extracellular Matrix Proteins 16 LRP3 17765984 Mol. Biochem. Parasitol. 2007 10.1016/j.molbiopara.2007.07.015 20 0 0 44 *Giardia lamblia|*Puromycin|*Neomycin B|Proteomics|*Transfection|*Gene Expression|Protozoan Proteins|Amino Acid Sequence|Blotting, Northern|Cell Nucleus|Transcriptional Activation|Cell Wall|Upregulation 16 LRP3 17298388 J. Neurochem. 2007 10.1111/j.1471-4159.2006.04418.x 18 0 0 44 Rats|Animals|*Avoidance Learning|Dentate Gyrus|Memory|*Gene Expression|Synaptic Plasticity|Hippocampus|Gene Expression Regulation|Neurons|mRNA|NF-kappa B 16 LRRC10 17626279 Dev. Dyn. 2007 PMC2002521 10.1002/dvdy.21225 9 0 1 52 Mice|Animals|*Leucine|Sarcoplasmic Reticulum|Cardiomyocytes|Muscle Proteins|Myocardium 16 LRRC10 17601532 Dev. Biol. 2007 PMC2048587 10.1016/j.ydbio.2007.06.005 13 0 1 52 Animals|Mice|*Zebrafish|Zebrafish Proteins|Animals, Genetically Modified|Gene Expression Regulation, Developmental|Morphogenesis|Cardiomyocyte|Congenital Heart Defects|Morpholinos|*Organogenesis|Gene Knockdown Techniques|myosin light chain 2|Myosin Light Chains 16 mex3b 17267406 Nucleic Acids Res. 2007 PMC1851655 10.1093/nar/gkm016 37 13 4 72 Animals|Humans|*RNA-Binding Proteins|mRNA|RNA|Caenorhabditis elegans|RING Finger Domains|HNRNPK protein, human|Heterogeneous-Nuclear Ribonucleoprotein K|Argonaute Proteins|Amino Acid Sequence|Phosphoproteins|Germ Line|Sequence Homology, Amino Acid 16 NOC3L 18029353 J. Biol. 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Care Med. 2007 PMC2048676 10.1164/rccm.200704-592OC 32 0 1 75 *Asthma|DNA-Binding Proteins|Genetic Predisposition to Disease|Transcription Factors|Polymorphism, Single Nucleotide|Linkage Disequilibrium|*Cloning, Molecular|ADAM Proteins 16 SCAPER 17698606 J. Cell Biol. 2007 PMC2064469 10.1083/jcb.200701166 24 33 2 22 *Cyclin A|CDK2 protein, human|CDK2 Protein|S Phase|Cell Cycle|Cyclin E|Cell Cycle Proteins|Cell Nucleus|Phases, G2|Mitosis|Nuclear Proteins|Transcription Factors|Phosphorylation|RNAi|Endoplasmic Reticulum 17 SCAPER 17553665 Mol. Cell. Probes 2007 10.1016/j.mcp.2007.04.001 1 0 0 22 Humans|*Tandem Repeat|Mutation|Gene Expression Profiling|Intron|RNA, Messenger 17 SH3BGRL3 17974098 Res. Commun. Mol. Pathol. Pharmacol. 2007 1 0 0 83 Rats|Animals|*Nickel|cDNA|Base Sequence|mRNA|Display, mRNA Differential|Metallothionein|DNA Damage|Downregulation|Up-Regulation|Kidney 16 UBR3 17462990 J. Biol. 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Genet. 2006 10.1038/ng1827 163 0 6 7 Humans|Mice|Animals|*Intranuclear Inclusions|polyglutamine|Spinocerebellar ataxia 8|*Spinocerebellar Degenerations|Spinocerebellar Ataxias|*Peptides|Trinucleotide Repeat Expansion|Nerve Tissue Proteins|Transgenic Mouse|RNA, Untranslated|Neurons|Cerebellum|RNA, Long Noncoding|Phenotype|Mutation|Disease Models, Animal|Brainstem 18 FOXS1 17062144 BMC Genomics 2006 PMC1634998 10.1186/1471-2164-7-271 10 0 0 119 Humans|Animals|*Vertebrate|*Comparative Genomics|Hox Genes|Gene Duplication|Evolution, Molecular|Multigene Family|Phylogeny|Sequence Alignment|Models, Genetic|Genome, Human 16 Gon4l 16545939 Genomics 2006 10.1016/j.ygeno.2006.02.002 12 0 0 45 Humans|Animals|*Segmental Duplications, Genomic|Gene Duplication|Evolution, Molecular|Multigene Family|*Human Chromosome|Phylogeny|World Monkey, New|Genome|Cebidae|Genomics|*Chromosome Structures 16 grwd1 16804918 Genes Chromosomes Cancer 2006 10.1002/gcc.20351 23 1 4 169 Humans|*Cell Transformation, Neoplastic|*Tumorigenesis|Colorectal Cancer|Nuclear Proteins|Ribosomes|Chromosomal Instability|Chromosome Segregation|*Chromosome Structures|GRWD1 protein, human|Carrier Proteins 16 HMGB4 17169924 Plant Cell Physiol. 2006 10.1093/pcp/pcl057 15 0 1 26 *Arabidopsis|*Plants, Transgenic|*Droughts|*Cold-Shock Response|*High Mobility Group Proteins|*Salinity|Arabidopsis Proteins|Germination|Gene Expression Regulation, Plant|Seedling 16 KIAA1279 16760737 Clin. Dysmorphol. 2006 10.1097/01.mcd.0000204991.84861.c9 1 0 0 164 Child|Male|Humans|Goldberg-Shprintzen megacolon syndrome|*Hirschsprung Disease|*Siblings|*Craniofacial Abnormalities|Microcephaly|Abnormalities, Multiple|Intellectual Disability|Hand Deformities, Congenital|Foot Deformities, Congenital|Developmental Disabilities|Growth Disorders|Toes|Cleft Palate|Syndrome 16 KIAA1462 16810331 Int. J. Biol. Sci. 2006 PMC1483122 10.7150/ijbs.2.171 9 0 0 64 Humans|Cattle|Animals|*Phenotypes|Single Nucleotide Polymorphisms|Genotype|Haplotypes|Quantitative Trait Locus|Gene Frequency|*Mammals|Promoter Regions, Genetic|Exon|Genetic Markers|cDNA 17 LRCH1 16891653 Rheumatology (Oxford) 2006 10.1093/rheumatology/kel265 5 0 3 44 Humans|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Gene Frequency|Knee Osteoarthritis|*Genetic Testing|Genotype|Osteoarthritis, Hip|Case-Control Studies|European Continental Ancestry Group|Newfoundland 16 LRCH1 16447229 Arthritis Rheum. 2006 10.1002/art.21624 14 0 2 44 Humans|*Single Nucleotide Polymorphism|*Osteoarthritis, Knee|*Genome-Wide Association Study|Genetic Predisposition to Disease|Gene Frequency|Osteoarthritis, Hip|Asian Continental Ancestry Group|Genotype|Case-Control Studies|European Continental Ancestry Group|*DNA|Nucleotides 16 EFHD1 16007190 Oncogene 2005 10.1038/sj.onc.1208794 41 1 1 78 Humans|*Carcinoma, Renal Cell|HEK293 Cells|Kidney Neoplasms|*Kidney|Gene Expression Profiling|DNA-Binding Proteins|*Epithelial Cells|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Hepatocyte Nuclear Factor 4|Pancreatic beta Cells|Cell Proliferation|ALDH5A1 protein, human|Succinate-Semialdehyde Dehydrogenase|Cobl protein, human|Microfilament Proteins|EFHD1 protein, human|Calcium-Binding Proteins 16 FOXS1 15964817 Mol. Cell. Biol. 2005 PMC1157007 10.1128/MCB.25.13.5616-5625.2005 18 1 2 119 Male|Animals|Mice|*Neural Crest|*Central Nervous System|*Gene Expression|GLB1 protein, human|beta-Galactosidase|Gene Expression Regulation, Developmental|Neurons|In Situ Hybridization|Transcription Factor|Reporter Gene|mRNA|Hypothalamus|*Body Weight 16 grwd1 15885502 Genomics 2005 10.1016/j.ygeno.2005.02.010 9 5 0 169 Humans|Animals|HL-60 Cell|Cellular Proliferation|Cell Differentiation|Retinoic Acid|Ribosomes|Downregulation|Protein Binding|Saccharomyces cerevisiae|*Hematopoiesis|Cell Nucleus|*Transcription Factors|GRWD1 protein, human|Carrier Proteins 16 KIAA1279 15883926 Am. J. Hum. Genet. 2005 PMC1226183 10.1086/431244 41 0 2 164 Humans|*Codon, Nonsense|Goldberg-Shprintzen megacolon syndrome|Disease, Hirschsprung's|Craniofacial Abnormalities|*Homozygote|Microcephaly|*Systems, Enteric Nervous|Mental Retardation|Abnormalities, Multiple|Pedigree|Syndrome|Nerve Tissue Proteins|KIAA1279 protein, human 16 PKD1L2 15765015 Postepy Hig Med Dosw (Online) 2005 0 0 0 9 *Polycystic Kidney, Autosomal Dominant|Polycystins|Mutation|Disease Progression|Genes, Regulator 16 SH3BGRL3 16143398 Mol. Immunol. 2005 10.1016/j.molimm.2005.07.039 9 2 1 83 Humans|*CD4-Positive T-Lymphocytes|*Lupus Erythematosus, Systemic|*T-Lymphocytes, Helper-Inducer|Gene Expression|Autoimmunity|Apoptosis|Cell Differentiation|*Genetic Profile|Genetic Techniques|TRIM22 protein, human|Tripartite Motif Proteins|Repressor Proteins|Minor Histocompatibility Antigens|KHSRP protein, human|Trans-Activators|RNA-Binding Proteins|HIG2 protein, human|ABCE1 protein, human 16 SH3BGRL3 15907482 FEBS Lett. 2005 10.1016/j.febslet.2005.04.011 3 0 0 83 Humans|Leukemia, Promyelocytic, Acute|Amino Acid Sequence|Tretinoin|Nuclear Magnetic Resonance, Biomolecular|TXN protein, human|Thioredoxin|Sequence Homology, Amino Acid|Carrier Proteins|*Magnetic Resonance Imaging|Cell Line, Tumor|SH3BGRL3 protein, human|Intracellular Signaling Peptides and Proteins 16 STXBP5L 15659226 J. Neurochem. 2005 10.1111/j.1471-4159.2004.02890.x 0 0 0 36 Animals|*Isoforms|*Brain|Binding Protein|Nerve Tissue Proteins|Amino Acid Sequence|Alternative Splicing|Exons|*Mammals|R-SNARE Proteins|Syntaxin 1|cDNA|mRNA|Protein Structure, Tertiary|Cloning, Molecular|SNARE|Syntaxin Protein|In Situ Hybridization|Cell Membrane 16 THEMIS2 16219472 Cytokine 2005 10.1016/j.cyto.2005.08.008 4 1 1 62 Humans|Female|*Ovarian Cancer|*Interferon-gamma|Apoptosis|Cell Line, Tumor|*Carcinoma, Ovarian Epithelial|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|siRNA|mRNA|Upregulation|*Ovary|Intracellular Signaling Peptides and Proteins|RNA Interference 16 BCAS4 15326299 Proc. Natl. Acad. Sci. U.S.A. 2004 PMC516526 10.1073/pnas.0405490101 28 0 2 111 *Databases, Nucleic Acid|*Chromosome Aberrations|Oncogene Proteins, Fusion|In Situ Hybridization, Fluorescence|Gene Rearrangement|mRNA|DNA-Binding Proteins|Gene Fusions|Chromosomes 16 HMGB4 15209498 Biochemistry 2004 10.1021/bi0499009 9 0 0 26 *Zea mays|*HMGB1 Protein|HMGB Proteins|Plant Proteins|DNA-cellulose|DNA|Arabidopsis|Phosphorylation|Protein Kinase CK2|Plant Chromosome|Amino Acid Sequence|Protein Binding|Electrophoretic Mobility Shift Assay|Cellulose 16 HMGB4 15110790 Biochem. Biophys. Res. Commun. 2004 10.1016/j.bbrc.2004.03.193 4 0 1 26 *Tobacco|*Zea mays|*Seedlings|*HMGB1 Protein|*Ectopic Gene Expression|Plants, Transgenic|Arabidopsis Proteins|Arabidopsis|*Organogenesis, Plant|Plant Roots|Chromatin 16 NOC3L 15564382 J. Cell. Sci. 2004 10.1242/jcs.01546 9 1 0 95 Mice|Animals|3T3-L1|*Cell Differentiation|Adipocyte|CCAAT Enhancer Binding Protein|Adipogenesis|SREBF1 protein, human|Sterol Regulatory Element Binding Protein 1|CCAAT-Enhancer-Binding Protein-alpha|Peroxisome Proliferator-Activated Receptor gamma|Trans-Activators|RNA, Messenger|Cell Line|Blotting, Northern|Promoter Regions, Genetic|Ligands|*Mammals|cDNA|Cell Nucleus 16 PKD1L2 15203210 Genomics 2004 10.1016/j.ygeno.2004.02.008 19 8 1 9 Humans|Male|Adult|polycystic kidney disease 2 protein|polycystic kidney disease 1 protein|*TRPP Cation Channels|*Binding Protein|*G Protein|PKD1L1 protein, human|Polycystic Kidney, Autosomal Dominant|Amino Acid Sequence|PKD1L2 protein, human|*G-Protein-Coupled Receptors|Exons|Alternative Splicing|Sequence Homology, Amino Acid|Receptors, Cell Surface|Mutations|Kidney 16 SH3BGRL3 15120624 Biochem. Biophys. Res. Commun. 2004 10.1016/j.bbrc.2004.04.050 2 0 0 83 Animals|GLRX protein, human|*Glutaredoxins|TXN protein, human|Thioredoxin|Amino Acid Sequence|Protein Conformation|Binding Sites|Protein Folding|Models, Molecular|Glutathione|Cysteine|Escherichia coli|Redox 16 STXBP5L 14767561 Int. J. Oncol. 2004 6 0 0 36 Mice|Humans|Animals|Exons|Nucleotide Sequence|Amino Acid Sequence|Bioinformatics|Expressed Sequence Tags|Introns|SCRIB protein, human|Membrane Proteins|Sequence Homology, Amino Acid|Chromosome Mapping|Protein Structure, Tertiary|cDNA|Codon|Models, Genetic|*In Silico|mRNA|Drosophila|Tumor Suppressor Proteins 16 VPS13D 15498460 Genomics 2004 10.1016/j.ygeno.2004.04.012 60 0 6 60 18 HMGB4 12653554 Biochemistry 2003 10.1021/bi027350d 8 12 1 26 *Arabidopsis Proteins|*Arabidopsis|*HMGB Proteins|*Zea mays|*Phosphorylation|*Casein Kinase II|Chromatin|Plant Proteins|HMGB1 Protein|CSNK2A1 protein, human|Cell Nucleus|Amino Acid Sequence|High Mobility Group Proteins 16 LRP3 14596620 Biochemistry 2003 10.1021/bi034752s 14 5 2 44 Humans|*LDL-Receptor Related Protein|*Ligands|LDLR protein, human|*LDL Receptor|LDL-Receptor Related Protein-Associated Protein|Binding Sites|Carrier Proteins|Protein Binding|Amino Acid Sequence|alpha-Macroglobulins|LTF protein, human|Lactoferrin|Binding, Competitive|*Burkitt Lymphoma|Glycosylation 16 LRP3 12809483 Biochemistry 2003 10.1021/bi034081y 7 0 0 44 Humans|Animals|Mice|Proteomics|*Low Density Lipoprotein Receptor-Related Protein-1|*Signal Transduction Pathways|LDLR protein, human|Low Density Lipoprotein Receptor|Endocytosis|Amino Acid Sequence|Adaptor Proteins, Signal Transducing|Protein Structure, Tertiary|Genes, Tumor Suppressor|Amino Acid Motifs|Sequence Homology, Amino Acid|Yeast Two-Hybrid System|Lipoproteins, LDL|LRP3 protein, human|LDL-Receptor Related Proteins|LRP12 protein, human 16 PKD1L2 12782129 Genomics 2003 10.1016/s0888-7543(03)00048-x 25 1 1 9 Mice|Humans|Animals|polycystic kidney disease 2 protein|Polycystins|polycystic kidney disease 1 protein|Potter Type III Polycystic Kidney Disease|*Polycystic Kidney Diseases|Polycystic Kidney, Autosomal Dominant|*Genomes|Amino Acid Sequence|Exons|Sequence Homology, Amino Acid|Ion Channel|PKD1L2 protein, human|Receptors, G-Protein-Coupled|Genes, Regulator|Mutations|Kidney|PKD1L3 protein, human 16 RCBTB1 14565662 Leuk. Lymphoma 2003 10.3109/10428190309178782 3 0 0 75 Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Guanine Nucleotide Exchange Factor|13q deletion syndrome|*Chromosome Deletion|Genes, Tumor Suppressor|RASGRF1 protein, human|*ras-GRF1|Amino Acid Sequence|Gene Expression Regulation, Leukemic|Tumor Suppressor Proteins|*Chromosomes, Human, Pair 13|Chromosome Mapping|Cloning, Molecular|mRNA|*Chromosome Disorders|Gene Deletion|Transcription, Genetic 16 BCAS4 12378525 Genes Chromosomes Cancer 2002 10.1002/gcc.10121 41 0 3 111 Humans|Breast Cancer 3|*Breast Neoplasms|Gene Amplification|In Situ Hybridization, Fluorescence|Chromosome Mapping|Gene Expression Profiling|Cloning, Molecular|Exons|Tumor Cells, Cultured|*Chromosome Structures|Amino Acid Sequence|RNA, Messenger 16 MLIP 12213825 J. Biol. Chem. 2002 10.1074/jbc.M206886200 41 28 0 72 Humans|Mice|Animals|*C EBPbeta|*Transcriptional Activation|*Growth Hormone|*Phosphorylation|*Human Growth Hormone|Protein Binding|*Pituitary Hormones, Anterior|Transcription, Genetic|Promoter Regions, Genetic|Proto-Oncogene Proteins c-fos|Signal Transduction|Binding Sites|Cell Nucleus|3T3 Cells|Transfection|Cell Line|*Biochemical Phenomena|Immunoblotting 16 SH3BGRL3 12095696 Gene 2002 10.1016/s0378-1119(02)00602-9 18 0 2 83 Chlorocebus aethiops|Animals|Humans|TXN protein, human|*Thioredoxin|Amino Acid Sequence|Sequence Alignment|Cloning, Molecular|Luminescent Proteins|Base Sequence|Chromosome Mapping|Green Fluorescent Proteins|GLRX protein, human|Glutaredoxins|DNA, Complementary|Sequence Homology, Amino Acid|Blotting, Northern|Messenger RNA|Gene Expression|COS Cells|Glutamates 16 THEMIS2 12191572 Leuk. Res. 2002 10.1016/s0145-2126(02)00005-x 6 1 0 62 Humans|*HL-60 Cells|*Granulocytes|Leukemia, Promyelocytic, Acute|Tretinoin|*Hematopoiesis|Cell Differentiation|Monocytes|Neoplasm Proteins|Intracellular Signaling Peptides and Proteins|mRNA|Transcriptional Activation|Protein Isoforms|Up-Regulation 16 HMGB4 11694523 J. Biol. Chem. 2001 10.1074/jbc.M109503200 18 4 2 26 *High Mobility Group Chromosomal Proteins|*Casein Kinase II|*Zea mays|*Phosphorylation|AKT1 protein, human|*Protein Kinase B|*DNA|HMGB Proteins|HMGB1|Chromatin|Arabidopsis Proteins|Plant Proteins|Electrophoretic Mobility Shift Assay|HMGB2|Circular Dichroism|Amino Acid Sequence 16 LRP3 11642543 Mol. Neurobiol. 2001 10.1385/MN:23:1:53 31 0 1 44 LDLR protein, human|*Low Density Lipoprotein Receptor|*Endocytosis|*Signal Transduction|Cell Adhesion Molecules, Neuronal|Serine Endopeptidases|Nerve Tissue Proteins|Extracellular Matrix Proteins|Low Density Lipoprotein Receptor-Related Protein-1|Neurons|Alzheimer Disease|Ligands|Lipoproteins, LDL 16 SH3BGRL3 11444877 Biochem. Biophys. Res. Commun. 2001 10.1006/bbrc.2001.5169 3 0 0 83 Humans|GLRX protein, human|*Glutaredoxins|*Escherichia coli|TXN protein, human|Thioredoxin|Amino Acid Sequence|enhanced green fluorescent protein|Green Fluorescent Proteins|Sequence Alignment|Sequence Homology, Amino Acid|Bacterial Proteins|Redox|Cloning, Molecular|Models, Molecular|Cysteine|SH3BGR protein, human|Muscle Proteins 16 SH3BGRL3 11404387 J. Leukoc. Biol. 2001 1 1 0 83 Humans|Female|*Tissue Distribution|*Apoptosis|Tumor Necrosis Factor-alpha|Intracellular Signaling Peptides and Proteins|Apoptosis Regulatory Proteins|Neoplasm Proteins|Tumor Cells, Cultured|Gene Expression Regulation, Neoplastic|mRNA|Carrier Proteins 16 SH3BGRL3 11137621 Int. J. 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Cell. Biol. 2020 PMC7076251 10.1128/MCB.00434-19 1 0 0 57 EGFR protein, human|*Epidermal Growth Factor Receptor|*Cell Membrane|Protein Transport|Vesicular Transport Proteins|Endosomes|Lung Neoplasms|Endocytosis|Cell Movement|Signal Transduction|Golgi Apparatus|Protein Binding|RNA Interference 15 SLC22A24 32150922 Int J Mol Sci 2020 PMC7084758 10.3390/ijms21051791 2 0 0 1 *Avena|*Systems Biology|Organic Cation Transport Proteins|Organic Anion Transporters|Biological Transport|Carnitine|Multigene Family|Signal Transduction|Uric Acid|*Systems Analysis 15 SLC25A31 32174961 Front Genet 2020 PMC7056726 10.3389/fgene.2020.00068 0 0 0 20 Swine|Animals|*Transcriptome|Enterotoxigenic Escherichia coli|Fimbriae Proteins|Escherichia coli Infections|Fimbriae, Bacterial|*Intestine, Small|Escherichia coli Proteins|Diarrhea|Swine Diseases|Bacterial Adhesion|*Cells, Epithelial 15 SMR3B 32675658 Am. J. Surg. 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Rep. 2019 PMC6395299 10.1042/BSR20182152 0 37 0 132 *Cell Differentiation|Myoblasts|Proto-Oncogene Proteins c-akt|Myogenin|Phosphatidylinositol 3-Kinases|Phosphoinositide-3 Kinase Inhibitors|Signal Transduction|p38 Mitogen-Activated Protein Kinases|Myogenic Regulatory Factors|Phosphorylation|Chromones|Morpholines 15 AKIRIN1 30746755 J. Cell. Biochem. 2019 10.1002/jcb.28406 0 0 0 132 Mice|Animals|*Muscle Fibers, Skeletal|MSTN protein, human|Myostatin|Myogenesis|Muscle, Skeletal|Myosin Heavy Chains|Nuclear Protein|Hypertrophy|Gene Expression|Akirin1 protein, mouse 15 ANKLE1 31509622 Int. J. Cancer 2019 10.1002/ijc.32677 0 0 0 68 Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Colorectal Neoplasms|Genotype|Case-Control Studies|Risk Factors 15 ARPP21 31653410 Neurobiol. Aging 2019 10.1016/j.neurobiolaging.2019.09.013 0 3 0 59 Humans|*Amyotrophic Lateral Sclerosis|*DNA Mutational Analysis|Genetic Association Studies|Exon|Mutation|Genetic Predisposition to Disease|Genotype|Asian Continental Ancestry Group|Cohort Studies|Mainland China|GLT8D1 protein, human|Glycosyltransferases 15 ARPP21 31208937 Environ Int 2019 PMC6754789 10.1016/j.envint.2019.03.071 4 0 0 59 *Particulate Matter|*DNA Methylation|*Epigenome|*Air Pollution|Air Pollutants|Environmental Exposure|Cardiovascular Diseases 15 C2CD4A 31692061 J. Cell. Biochem. 2019 10.1002/jcb.29550 0 0 0 19 Humans|*Prognosis|*Transcriptome|*Chemotherapy, Adjuvant|Neoplasm Recurrence, Local|Nomograms|Disease-Free Survival|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|RNA, Long Noncoding|Biomarkers, Tumor|Kaplan-Meier Estimate|mRNA|Risk Factors|Receiver Operating Characteristic|SPESP1 protein, human|Carrier Proteins|Seminal Plasma Proteins 15 C2CD4A 31527256 Proc. Natl. Acad. Sci. U.S.A. 2019 PMC6778232 10.1073/pnas.1904311116 1 0 0 19 Genome-Wide Association Study|Diabetes Mellitus, Type 2|Insulin-Secreting Cells|Insulin Secretion|Insulin|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Transcription Factors|Genotype 15 CLUH 31354474 Front Pharmacol 2019 PMC6635586 10.3389/fphar.2019.00727 3 1 0 105 *Proteome|*Interferon|*CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Lymphocyte Activation|T-Lymphocytes, Helper-Inducer|CD3 Complex|Antigens, Differentiation, T-Lymphocyte|*Mitochondria|Cytokines|*Antiviral Agents 15 CLUH 31048716 Sci Rep 2019 PMC6497719 10.1038/s41598-019-43410-4 0 3 0 105 Mice|Animals|*Adipogenesis|*Mitochondria|UCP1 protein, human|Uncoupling Protein 1|Brown Adipocyte|Mitochondrial Proteins|Gene Expression Regulation|3T3-L1 Cells|Cell Differentiation|Mitochondrial Biogenesis|mRNA|Cytosol 15 CLUH 30741581 Crit. Rev. Biochem. Mol. Biol. 2019 10.1080/10409238.2018.1553927 0 0 0 105 *Mitochondria|*RNA-Binding Proteins|Mitochondrial Proteins|RNA, Mitochondrial|mRNA|Protein Biosynthesis|Gene Expression Regulation|Proteome 15 CMTM1 31784415 Mol. Ther. 2019 PMC7000997 10.1016/j.ymthe.2019.10.018 1 0 0 8 Dogs|Animals|Mice|*Transcriptome|*Myotubular Myopathy, X-Linked|*Genetic Therapy|Dependovirus|Protein Tyrosine Phosphatases, Non-Receptor|Muscle Contraction|Genetic Vectors|Muscle, Skeletal|Disease Models, Animal 15 CMTM1 31754330 Int. J. Biol. Sci. 2019 PMC6854381 10.7150/ijbs.33733 1 1 0 8 Male|Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|MARVEL Domain-Containing Proteins|Chemokines|Signal Transduction 15 CMTM1 31542285 Exp. Cell Res. 2019 10.1016/j.yexcr.2019.111623 0 2 0 8 Male|Humans|Mice|Animals|*Protein A|*Apoptosis|Caspases|Apoptosis Regulatory Proteins|Mitochondria|*Lymphoma|Endoplasmic Reticulum|Caspase 3|Proto-Oncogene Proteins c-bcl-2|Cytochromes c|Cell Line, Tumor|CAMLG protein, human|Adaptor Proteins, Signal Transducing|Signal Transduction 15 ERGIC2 31180552 Mol Med Rep 2019 PMC6579992 10.3892/mmr.2019.10294 2 1 0 139 Humans|*Squamous Cell Carcinoma of Head and Neck|*Prognosis|DNA Methylation|Head and Neck Neoplasms|Network, Gene|Carcinoma, Squamous Cell|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Transcriptome|Biomarkers, Tumor 15 ERGIC2 31142615 J. Biol. Chem. 2019 PMC6635435 10.1074/jbc.RA119.007435 1 9 0 139 Humans|*E3 Ubiquitin Ligase|*Protein Transport|Golgi Apparatus|Ubiquitination|Carrier Proteins|Endoplasmic Reticulum|Membrane Proteins|Saccharomyces cerevisiae|*Cell Movement|Secretory Pathway|MARCH2 protein, human|ERGIC3 protein, human 15 FGGY 31341893 Biomed Res Int 2019 PMC6614983 10.1155/2019/2951427 2 0 0 8 Female|Swine|Animals|*RNA, Long Noncoding|*Transcriptome Analysis|Transcriptome|Sequence Analysis, RNA|*Muscle|Gene Ontology|Exons|Quantitative Trait Locus|Lipid Metabolism|Liver|*Musculoskeletal System 15 FGGY 31289132 Cancer Res. 2019 10.1158/0008-5472.CAN-19-0076 2 3 0 8 *Genes, Suppressor|*Carcinoma, Squamous Cell|*Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Disease Progression|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|RNA, Long Noncoding|Prognosis|MicroRNAs|Gene Regulatory Networks|Gene Expression Profiling|Cell Line, Tumor|*Long Interspersed Nucleotide Elements 15 FOXRED1 31434271 J Clin Med 2019 PMC6723710 10.3390/jcm8081262 0 0 0 26 Humans|Mitochondrial complex I deficiency|Electron Transport Complex I|Disorder, Mitochondrial|Mitochondria|Mitochondrial Proteins|Molecular Chaperones|Oxidative Phosphorylation|Homozygote|Flavin-Adenine Dinucleotide|Mutations|Nicotinamide Adenine Dinucleotide|Oxidoreductases|FOXRED1 protein, human 16 FOXRED1 31273716 Methods Mol. Biol. 2019 10.1007/978-1-4939-9554-7_27 0 0 0 26 Animals|Humans|Infant, Newborn|*Leigh Disease|Neurodegenerative Diseases|Electron Transport Complex I|*Disease Models, Animal|DNA, Mitochondrial|Brain|Mutation|FOXRED1 protein, human|Molecular Chaperones 16 FOXRED1 31065540 Mol Genet Metab Rep 2019 PMC6495215 10.1016/j.ymgmr.2019.100472 0 1 0 26 Humans|Infant|*Acidosis, Lactic|Electron Transport Complex I|Mitochondrial Proteins|Homozygote|Mitochondria|Mutation|*Hypertension, Pulmonary|Cysts|FOXRED1 protein, human|Molecular Chaperones 16 FOXRED1 30723688 Mol Genet Metab Rep 2019 PMC6349952 10.1016/j.ymgmr.2018.12.006 3 0 0 26 Humans|Infant|*Acidosis, Lactic|Electron Transport Complex I|Mitochondrial Diseases|*Metabolism, Inborn Errors|Homozygote|Mitochondria|Mutation|*Hypertension, Pulmonary|Genetic Predisposition to Disease|Cysts|FOXRED1 protein, human|Molecular Chaperones 16 FUBP3 31189591 Proc. Natl. Acad. Sci. 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J. Oncol. 2019 PMC6910184 10.3892/ijo.2019.4926 0 1 0 19 Humans|*Computational Biology|*Prognosis|Gene Modules|Gene Ontology|*Lung Cancer|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kinesin|Survival Analysis|PTK2 protein, human|Focal Adhesion Kinase 1 15 IGSF10 31293522 Front Endocrinol (Lausanne) 2019 PMC6606719 10.3389/fendo.2019.00423 1 4 0 19 Humans|Sexual Maturation|Hypogonadism|Gonadotropin-Releasing Hormone|Mutations|Gene Expression Regulation 15 IGSF10 31200363 Eur. J. Endocrinol. 2019 10.1530/EJE-18-0764 6 0 0 19 *Hypogonadism|Kallmann Syndrome|Pedigree|Sequencing, Next-Generation|*Cohort Studies|Nerve Tissue Proteins|Mutation|Gn-RH 15 IGSF10 31042289 J. Clin. Endocrinol. Metab. 2019 PMC6563799 10.1210/jc.2019-00248 4 0 0 19 Humans|Female|*Menopause, Premature|*Primary Ovarian Insufficiency|*Exome|*Whole Exome Sequencing|Pedigree|*Cohort Studies|Genetic Predisposition to Disease|Chromosomal Abnormalities|Amenorrhea 15 LINC00324 31858541 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201912_19775 0 0 0 2 Humans|*RNA, Long Noncoding|*Colorectal Cancer|MicroRNAs|Cell Proliferation|Cell Movement|HCT116 Cells|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Colonic Neoplasms|MIRN214 microRNA, human 15 LINC00324 31750827 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2019 0 0 0 2 Humans|*Immunophenotyping|*Leukemia, Myeloid, Acute|CD33 protein, human|Sialic Acid Binding Ig-like Lectin 3|CD163 antigen|Antigens, Differentiation, Myelomonocytic|Antigens, CD|HLA-DR|Flow Cytometry|PTPRC protein, human|Leukocyte Common Antigens|*Leukocytes 15 LINC00324 31565549 PeerJ 2019 PMC6743450 10.7717/peerj.7456 3 0 0 2 *RNA, Long Noncoding|*Prognosis|miRNAs|*Laryngeal Neoplasms|mRNA|*Squamous Cell Carcinoma of Head and Neck|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Disease Progression|Head and Neck Neoplasms 15 LINC00324 31462944 EPMA J 2019 PMC6695468 10.1007/s13167-019-00175-0 7 3 0 2 Humans|Female|*RNA, Long Noncoding|*mRNA|*Precision Medicine|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Gene Modules|Prognosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate 15 LINC00324 31225659 J. 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Physiol. 2019 10.1002/jcp.28973 3 1 0 2 Humans|*Osteosarcoma|RNA, Long Noncoding|Cell Proliferation|Gene Expression Regulation, Neoplastic|WDR66 protein, human|*Calcium-Binding Proteins|ELAVL1 protein, human|ELAV-Like Protein 1|MicroRNAs|Cell Movement|Cell Line, Tumor|Upregulation|Oncogenes|Disease Progression|Prognosis 15 MMP27 31200666 BMC Cancer 2019 PMC6567474 10.1186/s12885-019-5768-0 7 0 0 4 *Prognosis|*Transcriptome|*MMPs|Tissue Inhibitor of Metalloproteinase-2|Matrix Metalloproteinase 9|Gene Expression Regulation, Neoplastic|*Cancer|*Microarray Analysis|RNA, Messenger 15 MMP27 31067818 Genes (Basel) 2019 PMC6562980 10.3390/genes10050347 1 0 0 4 Pregnancy|Humans|Female|Case-Control Studies|*Abortion, Habitual|Single Nucleotide Polymorphisms|Gene Frequency|Genetic Predisposition to Disease|Genetic Association Studies|Alleles|Genotype|*Matrix Metalloproteinases 15 MMP27 30850364 Cancer Genomics Proteomics 2019 PMC6489687 10.21873/cgp.20118 3 0 0 4 Male|*Proteomics|Electrophoresis, Gel, Two-Dimensional|Proteome|Neoplasm Proteins|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Biomarkers, Tumor|Blood Proteins 15 NAA25 31744933 Plant Physiol. 2019 PMC6997699 10.1104/pp.19.00792 2 3 0 77 *Acetylation|N-Terminal Acetyltransferase B|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|*Protein Processing, Post-Translational|Acetyltransferases|Substrate Specificity|*Biological Phenomena|NatB protein, S cerevisiae 15 NAA25 30656483 J. Thromb. Thrombolysis 2019 10.1007/s11239-018-01802-9 0 0 0 77 Male|Female|Child|Humans|*Acute Stroke|Brain Ischemia|HDAC9 protein, human|*Histone Deacetylases|Genetic Predisposition|*Repressor Proteins|Polymorphism, Single Nucleotide|Risk Factors|*Prognosis|*Genes, cdc|Case-Control Studies|*Arteries|Cell Adhesion Molecules, Neuronal|CDKN2B protein, human|Cyclin-Dependent Kinase Inhibitor p15|NINJ2 protein, human 15 NDNF 31883645 Am. J. Hum. Genet. 2019 PMC7042563 10.1016/j.ajhg.2019.12.003 1 0 0 53 Sexual Maturation|*Hypogonadism|Kallmann Syndrome|Gonadotropin Releasing Hormone|*Neurons|enovin|*Nerve Growth Factors|NTF3 protein, human|Pedigree|Axons|Mutation|Cell Movement|Fibrinogen|Cohort Studies 15 NDNF 31852841 JCI Insight 2019 PMC6975268 10.1172/jci.insight.129344 0 0 0 53 Humans|Animals|Mice|Adult|*Lung Cancer|CpG Island|enovin|*Nerve Growth Factors|NTF3 protein, human|DNA Methylation|*Neurons|Adenocarcinoma|Promoter Regions, Genetic|Lung Adenocarcinoma|Downregulation|Lung 15 NDNF 31287219 J. Cell. Mol. Med. 2019 PMC6714174 10.1111/jcmm.14456 2 0 0 53 Humans|Mice|Animals|Aged|Adolescent|Young Adult|Adult|Middle Aged|Aged, 80 and over|*Rejuvenation|Osteogenesis|Hematopoietic Stem Cell Transplantation|Transplantation, Autologous|enovin|*Nerve Growth Factors|NTF3 protein, human|*Adipocytes|*Neurons|Cell Differentiation|Stem Cells|*Myocardial Infarction|Adipose Tissue|*Transforming Growth Factor beta|Neovascularization, Physiologic|Cell Survival 15 NDNF 30867731 Oncol Lett 2019 PMC6396104 10.3892/ol.2019.9937 2 1 0 53 Humans|*Carcinoma, Renal Cell|*Epithelial-Mesenchymal Transition|Kidney Neoplasms|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|MicroRNAs|RNA Interference|Cell Line, Tumor|Downregulation|enovin|Nerve Growth Factors|Transforming Growth Factor beta|NTF3 protein, human 15 RSRC1 31257492 Mol Med Rep 2019 PMC6625388 10.3892/mmr.2019.10409 1 1 0 134 Humans|*Stomach Neoplasms|PTEN protein, human|*PTEN Phosphohydrolase|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Gastritis, Hypertrophic|MicroRNAs|Cell Line, Tumor|Tensin|Downregulation|Signal Transduction|Cell Cycle|RSRC1 protein, human|Nuclear Proteins 15 RUSC2 31199889 Biochem. Cell Biol. 2019 10.1139/bcb-2019-0031 1 9 0 57 Prospective Studies|Myocytes, Smooth Muscle|*Upregulation|Muscle, Smooth, Vascular|Cell Proliferation|MicroRNAs|Cell Movement|Cell Differentiation|*Transcriptional Activation|Cells, Cultured|Phenotypes|Binding Sites 15 RUSC2 31067441 Structure 2019 10.1016/j.str.2019.04.011 0 0 0 57 Rats|Animals|ADP-Ribosylation Factors|rab GTP-Binding Proteins|GTPase-Activating Proteins|Neurites|PC12 Cells 15 RUSC2 30905672 Structure 2019 10.1016/j.str.2019.02.008 2 5 0 57 Rats|Humans|Animals|ADP-Ribosylation Factors|rab GTP-Binding Proteins|GTPase-Activating Proteins|Neurites|Protein Transport|PC12 Cells|Protein Binding|Cell Movement|Ankyrin Repeat|RUSC2 protein, human|Carrier Proteins|RAB35 protein, human 15 SLC22A24 31553721 PLoS Genet. 2019 PMC6760779 10.1371/journal.pgen.1008208 2 0 0 1 Humans|Animals|*Genome-Wide Association Study|Phylogeny|*Steroids|Organic Cation Transport Proteins|Symporters|androsterone glucuronide|Androsterone|Biological Transport|SNPs|Bile Acids 15 SMR3B 31297036 Cancer Cell Int. 2019 PMC6599314 10.1186/s12935-019-0884-0 0 0 0 14 Humans|*Triple-Negative Breast Cancer|*Prognosis|RNA, Long Noncoding|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Biomarkers, Tumor|RNA, Messenger|Bioinformatics 15 SSH2 31824193 Cancer Manag Res 2019 PMC6900270 10.2147/CMAR.S221150 0 1 0 99 *Down-Regulation|*Cancer Stem Cells|*Colonic Neoplasms|MIRN194 microRNA, mouse|*MicroRNAs|Colorectal Cancer|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|*Colon|Apoptosis 15 SSH2 30809968 Mol Genet Genomic Med 2019 PMC6503031 10.1002/mgg3.605 2 0 0 99 *Exome|*Whole Exome Sequencing|Germ-Line Mutation|Colorectal Cancer|Genetic Predisposition to Disease|Pedigree|Heterozygote|Phenotype 15 TBCK 31331056 Int J Mol Sci 2019 PMC6679220 10.3390/ijms20143540 0 3 0 56 Humans|*Cisplatin|*MicroRNAs|*Carcinoma, Renal Cell|3' Untranslated Region|Renal Cancer|Drug Resistance, Neoplasm|Gene Expression Regulation, Neoplastic|Antineoplastic Agents|RNA Interference|Cell Line, Tumor|Apoptosis|CASP3 protein, human|Procaspase-3|Anti-miRs|Cell Proliferation|siRNA|Genes, Tumor Suppressor|Binding Sites 16 TP53I11 30940320 BMB Rep 2019 PMC6605526 0 4 0 22 *Epithelial-Mesenchymal Transition|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Neoplastic Processes|Anoikis|Cell Proliferation|Upregulation|Nuclear Proteins|Signal Transduction|Xenografts 15 TUT1 31162284 Am. 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Pathol. 2019 10.1097/PAS.0000000000001301 1 0 0 217 *Carcinoma, Intraductal, Noninfiltrating|In Situ Hybridization, Fluorescence|*Gene Fusions|Salivary Gland Neoplasms|*Transcription Factors|Proto-Oncogenes|Gene Rearrangement|Proto-Oncogene Proteins c-ret|Biomarkers, Tumor|Cystadenocarcinoma|Sequencing, Next-Generation|Mutations 15 ZBTB7C 31222731 FEBS Lett. 2019 10.1002/1873-3468.13501 0 0 0 57 Mice|Animals|*Knockout Mouse|*Transcription Factor|*Pulmonary Emphysema|*Emphysema|*Lungs|*MMPs|*Gene Expression Regulation|Smoke|*Phenotype|Transcription, Genetic|Pulmonary Alveoli|Cigarette Smoking 15 ZBTB7C 30959128 Biochim Biophys Acta Gene Regul Mech 2019 10.1016/j.bbagrm.2019.04.001 2 3 0 57 Mice|Animals|*Gluconeogenesis|*Glucose-6-Phosphatase|*Fasting|*Transcription Factor|Phosphoenolpyruvate Carboxykinase (GTP)|*Gene Expression Regulation|Hepatocytes|Liver|Mice, Knockout|Insulin|Blood Glucose|Glucose|Transcription, Genetic|Promoter Regions, Genetic|Forkhead Box Protein O1|Activation, Transcriptional|Intracellular Signaling Peptides and Proteins|Upregulation 15 ZNF219 31007729 Exp Ther Med 2019 PMC6468394 10.3892/etm.2019.7349 0 0 0 67 *Transcriptome|Gene Regulatory Networks|Gene Expression Profiling|Transcription Factors|Oligonucleotide Array Sequence Analysis|Protein Interaction Maps|*Osteoporosis|Databases, Genetic 15 ZNF219 30828972 FEBS J. 2019 10.1111/febs.14800 0 6 0 67 *Nucleosome Remodeling and Deacetylase Complex|*Nucleosomes|*Cell Lines|Chromatin Assembly and Disassembly|DNA Helicases|Chromatography, Liquid 15 ZNF81 31727082 Cell Commun. Signal 2019 PMC6854687 10.1186/s12964-019-0448-x 1 0 0 22 Pregnancy|Female|Humans|*Trophoblasts|*Endometrium|Embryo Implantation|*Embryo, Mammalian|*Extracellular Vesicles|*Cells, Epithelial|*Gene Expression|Coculture Techniques|*Cell Physiological Phenomena 15 ANKLE1 29879106 PLoS Genet. 2018 PMC6007928 10.1371/journal.pgen.1007453 2 6 0 68 Animals|*Caenorhabditis elegans|*Chromosome Segregation|*Recombinational DNA Repair|Caenorhabditis elegans Proteins|Meiosis|Crossing Over, Genetic|*Endonucleases|*Homologous Recombination|*DNA Repair|DNA, Cruciform|Endodeoxyribonucleases|DNA Breaks, Double-Stranded|DNA Helicases|Chromosomal Proteins, Non-Histone|DNA-Binding Proteins|Chromatin|LEM-3 protein, C elegans 15 ANKLE1 29463814 Nat Commun 2018 PMC5820297 10.1038/s41467-018-03135-w 5 13 0 68 Animals|Humans|*Chromatin|Caenorhabditis elegans|*Mitosis|Caenorhabditis elegans Proteins|*Spindle Apparatus|Chromosome Segregation|AURKB protein, human|Aurora Kinase B|*Endonucleases|Chromosomes|*DNA|Genome|DNA Replication|Deoxyribonucleases|LEM-3 protein, C elegans|Endodeoxyribonucleases 15 ARPP21 29581509 Nat Commun 2018 PMC5964322 10.1038/s41467-018-03681-3 6 17 0 59 Humans|Mice|Animals|*miRNAs|*RNA Binding Protein|3' UTRs|RNA Processing, Post-Transcriptional|mRNA|Binding Sites|Introns|Gene Expression Regulation|HEK293 Cells 15 C2CD4A 29625024 Am. J. Hum. Genet. 2018 PMC5985342 10.1016/j.ajhg.2018.02.020 8 0 0 19 Humans|Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Insulin-Secreting Cells|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Alleles|Insulin|Enhancer Elements, Genetic|Proinsulin|Chromosome Mapping 15 C2CD4A 29444352 Diabet. Med. 2018 10.1111/dme.13602 0 0 0 19 Humans|*Alleles|*Diabetes Mellitus, Type 2|*Case-Control Studies|*Incidence|Japan|Transcription Factor 7-Like 2 Protein|Zinc Transporter 8|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cyclin-Dependent Kinase Inhibitor p15|Homeodomain Proteins|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Transcription Factors|tRNA Methyltransferases|Asian Continental Ancestry Group|*Risk Factors|Cyclin-Dependent Kinase 5|Potassium Channels, Inwardly Rectifying 15 CLUH 30509291 Virol. J. 2018 PMC6276163 10.1186/s12985-018-1056-x 0 0 0 105 Humans|Dogs|Animals|*Influenza A virus|*Active Transport, Cell Nucleus|*Influenza, Human|*Methionine|Virus Assembly|Viral Matrix Proteins|*Racemethionine|Virus Replication|Madin Darby Canine Kidney Cells|RNA, Viral|HEK293 Cells|Cytoplasm|Virion|Amino Acid Sequence 15 CLUH 31105137 Uirusu 2018 10.2222/jsv.68.71 0 0 0 105 *RNA Virus|*Virus Replication|nucleoprotein VP40, Ebola virus|Nucleoproteins|Viral Proteins|RNA, Viral|Viral Core Proteins|Host-Pathogen Interactions|Orthomyxoviridae|Genome, Viral|*DNA Viruses|Enterovirus|Enterovirus Infections 15 CMTM1 30209135 J. Cell. Sci. 2018 PMC6198454 10.1242/jcs.221481 4 0 0 8 Male|Mice|Animals|Sperm-Ovum Interactions|Spermatozoa|Fertility|ADAM Proteins|Membrane Glycoproteins|ADAM 3|*Retinoids|Calcium-Binding Proteins|Adam3 protein, mouse 15 DUSP11 30451863 Nat Commun 2018 PMC6242832 10.1038/s41467-018-07314-7 17 0 0 83 Humans|*Herpesvirus 8, Human|DDX58 protein, human|*DEAD Box Protein 58|Interferon-Induced Helicase, IFIH1|Immunity, Innate|RNA, Viral|RNA Viruses|*Cellular Immune Response|Signal Transduction|*Sensory Receptor|RNA, Small Interfering|Infections|DUSP11 protein, human|Dual-Specificity Phosphatases 15 DUSP11 30038017 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6094126 10.1073/pnas.1802326115 6 1 0 83 *Hepacivirus|RNA triphosphatase|*Hepatitis C|*Acid Anhydride Hydrolases|Hepatocellular Carcinoma|RNA, Viral|Virus Replication|Liver Neoplasms|MicroRNAs|*Exonucleases|Host-Pathogen Interactions|Exoribonucleases|Hepatocytes 15 DUSP11 29672716 Nucleic Acids Res. 2018 PMC6007490 10.1093/nar/gky273 10 26 0 83 *Hepatitis C virus|*Pyrophosphatases|*Hepatitis C|RNA, Viral|Virus Replication|Viral Genome|Exoribonucleases|MicroRNAs|RNA Stability|5' Untranslated Regions|Host-Pathogen Interactions|Hepatocytes|Exonucleases|Cell Line, Tumor 15 FOXRED1 30392038 Metab Brain Dis 2018 10.1007/s11011-018-0334-z 0 0 0 26 Mice|Animals|*Leigh Disease|*Disease Models, Animal|Corpus Striatum|Substantia Nigra|Electron Transport Complex I|Disorders, Mitochondrial|Mice, Inbred C57BL|Dopamine 16 FUBP3 30139389 Clin Epigenetics 2018 PMC6108111 10.1186/s13148-018-0543-7 9 9 0 105 Humans|*DNA Methylation|*Smoking|CpG Islands|Whites|Epigenesis, Genetic|*Tobacco Smoking|Epigenetic|Japanese Americans|Nicotine|Smokers|Genome-Wide Association Study|Lung Cancer|Leukocytes|Hawaii 15 gal3st1 30400820 Breast Cancer Res. 2018 PMC6219063 10.1186/s13058-018-1058-z 2 5 0 36 SELP protein, human|*P-Selectin|*Sulfoglycosphingolipids|Apoptosis|Cell Line, Tumor|Galactosylceramides|*Neoplastic Processes|*Cell Death 15 gal3st1 29317492 J. Biol. Chem. 2018 PMC5836135 10.1074/jbc.M117.807487 5 34 0 36 Humans|*Leucine|*Protein Interaction Maps|HEK293 Cells|*Growth Factor Receptors|ErbB Receptors|*Immunoglobulin-like Domains|Membrane Glycoproteins|Membrane Proteins|Downregulation|Genes, Tumor Suppressor|Receptor Protein-Tyrosine Kinases|Signal Transduction|Cell Line, Tumor|*Protein Domains|GLRX3 protein, human|Carrier Proteins|LRIG1 protein, human 15 GREB1L 30219030 BMC Evol. Biol. 2018 PMC6139179 10.1186/s12862-018-1255-5 3 0 0 24 Animals|*Oncorhynchus mykiss|*Genome|*Genomics|Animal Migration|Phenotype|Polymorphism, Single Nucleotide 15 GREB1L 29955957 Hum. Genet. 2018 PMC6082420 10.1007/s00439-018-1898-8 3 0 0 24 Mice|Animals|Labyrinth, Membranous|Deafness, Autosomal Recessive 4|Hearing Loss, Sensorineural|Zebrafish|Eighth Cranial Nerve|Whole Exome Sequencing|Hearing|Mice, Knockout|Vestibular Aqueduct 15 GREB1L 29945667 Neural Dev 2018 PMC6020313 10.1186/s13064-018-0112-y 1 19 0 24 Animals|*Zebrafish|*Hindbrain|Zebrafish Proteins|Transcription Factors|Embryo, Nonmammalian|Body Patterning|Homeodomain Proteins|Gene Expression Regulation, Developmental|Fibroblast Growth Factors|Retinoic Acid|Morphogenesis|Nerve Tissue Proteins|In Situ Hybridization|MafB Transcription Factor|Hepatocyte Nuclear Factor 1-beta|Neurons|*Gene Expression|Signal Transduction 15 GRID2IP 30009200 Ann Clin Transl Neurol 2018 PMC6043775 10.1002/acn3.582 12 2 0 15 Humans|*Alzheimer Disease|*Whole Exome Sequencing|LDL-Receptor Related Proteins|Genetic Predisposition to Disease|Gene Frequency|Genome-Wide Association Study|Exome|Genetic Variation|Membrane Transport Proteins|Case-Control Studies|Mutation|Risk Factors 15 IGSF10 30467832 Clin. Genet. 2018 10.1111/cge.13482 2 1 0 19 Humans|*Kallmann Syndrome|*Prevalence|Idiopathic Hypogonadotropic Hypogonadism|Hypogonadism|FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|Phenotype|Mutation|Pedigree|Heterozygote|Gn-RH|Cohort Studies|Mutation, Missense|CCDC141 protein, human|Nerve Tissue Proteins 15 IGSF10 29730183 Mol. Cell. Endocrinol. 2018 PMC6127442 10.1016/j.mce.2018.05.001 3 12 0 19 Male|Female|Humans|Genome-Wide Association Study|Sexual Maturation|Gn-RH|Pedigree|Genetic Predisposition to Disease|Gene Expression Regulation|Phenotype|Mutation 15 ILDR2 29847571 PLoS ONE 2018 PMC5976177 10.1371/journal.pone.0197548 0 5 0 19 Male|Mice|Animals|Follow-Up Studies|*C57BL Mice|Liver|Lipid Metabolism|Hepatocyte|Non-alcoholic Fatty Liver Disease|Mice, Knockout|Triglycerides|Signal Transduction|shRNA|Gene Knockdown Techniques|Obesity|ILDR2 protein, mouse|Membrane Proteins 15 ILDR2 29631364 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2018 PMC6139612 10.1152/ajpregu.00431.2017 0 1 0 19 Animals|*Oncorhynchus mykiss|*Gills|*Tight Junctions|*Epithelium|Tight Junction Proteins|Epithelial Cells|Cultured Cells|Fish Proteins|mRNA|Permeability|Cell Line|Hydrocortisone 15 ILDR2 29494550 Int J Mol Sci 2018 PMC5877567 10.3390/ijms19030706 9 5 0 19 Mice|Animals|*Microglia|Aging|Cerebral Cortex|Central Nervous System|Macrophage Activation|Fluorescence Activated Cell Sorting|Phenotype|Transcriptome 15 ILDR2 29431694 J. Immunol. 2018 PMC6860365 10.4049/jimmunol.1700325 0 0 0 19 Humans|*T Cells|Lymphocyte Activation|B7-1 Antigen|B7 Antigens|Immunoglobulin Fc Fragments|Cytokines|Membrane Glycoproteins|Macrophages 15 ILDR2 29431690 J. Immunol. 2018 PMC6830572 10.4049/jimmunol.1700326 1 0 0 19 Animals|*Immune Tolerance|*Antigens|Islets of Langerhans Transplantation|Diabetes Mellitus, Type 1|Pancreatic Islet|Bone Marrow Transplantation|T-Lymphocytes, Regulatory|Graft Survival|Transplantation, Homologous|Diabetes Mellitus, Experimental|Experimental Autoimmune Encephalomyelitis|Immunoglobulin Fc Fragments|*Homeostasis 15 LINC00324 30556874 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201812_16531 4 8 0 2 *Tumor Promoters|*Lung Adenocarcinoma|Long Non-Coding RNA|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|MicroRNAs|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|A549 Cells|Cell Proliferation|Epithelial-Mesenchymal Transition|Proto-Oncogene Proteins c-akt|Cell Line, Tumor|Apoptosis|Signal Transduction|*Cell Transformation, Neoplastic 15 LINC00324 30146820 Clin. Lab. 2018 10.7754/Clin.Lab.2018.180136 1 0 0 2 Humans|*RNA, Long Non-Coding|*Thymoma|*Prognosis|Tumor Markers|Gene Expression Regulation, Neoplastic|*Thymus Neoplasms|Kaplan-Meier Estimate|Gene Expression Profiling 15 LINC00324 29915327 Cell Death Dis 2018 PMC6006375 10.1038/s41419-018-0758-8 12 44 0 2 Humans|*RNA, Long Noncoding|*Stomach Neoplasms|Cell Proliferation|Prognosis|*Gastritis, Hypertrophic|Lymphatic Metastasis|Gene Expression Regulation, Neoplastic|Cell Cycle|Cell Movement|Upregulation|Cell Line, Tumor|Cell Transformation, Neoplastic|Apoptosis|Biomarkers, Tumor|Disease Progression 15 NAA25 30096757 J Clin Med 2018 PMC6111840 10.3390/jcm7080204 0 6 0 77 *Risk Factors|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|Gene Frequency|Body Mass Index|Genotype|Odds Ratio|Biomarkers|Prognosis 15 NAA25 30044982 Cell Rep 2018 PMC6296758 10.1016/j.celrep.2018.06.078 10 2 0 77 *Influenza A virus|*Acetylation|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|*Posttranslational Modification|Viral Nonstructural Proteins|Amino Acid Sequence|Acetyltransferases|Repressor Proteins|NatB protein, S cerevisiae 15 NAA25 29879492 Genomics 2018 10.1016/j.ygeno.2018.05.015 1 0 0 77 Humans|*Exome|Genome-Wide Association Study|Cross-Sectional Studies|Japan|*Dyslipidemia|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|Cholesterol, HDL|Cholesterol, LDL|Triglycerides|Phenotypes 15 NDNF 30269988 Neuron 2018 PMC6226614 10.1016/j.neuron.2018.09.001 10 0 0 53 Interneurons|*Learning|Pyramidal Neuron|Dendrites|Neocortex|Neural Inhibition|Neuronal Plasticity|Neurons|Optogenetics|Somatostatin|Electrophysiological Phenomena|Inhibition, Psychological 15 NDNF 30062183 JACC Basic Transl Sci 2018 PMC6059002 10.1016/j.jacbts.2017.07.014 7 12 0 53 Mice|Animals|Humans|*Mesenchymal Stem Cells|enovin|*Nerve Growth Factors|NTF3 protein, human|Mesenchymal Stem Cell Transplantation|Myocardial Infarction|Cell Survival|Apoptosis|*Neurons|Heart|Proto-Oncogene Proteins c-akt|Cell Senescence|Cells, Cultured|*Rejuvenation 15 NDNF 29860315 Nucleic Acids Res. 2018 PMC6061882 10.1093/nar/gky449 7 98 0 53 Humans|*Methylation|*Hypoxia-Inducible Factor 1|*Cell Migration|Gene Expression Regulation, Neoplastic|Histone-Lysine N-Methyltransferase|Glioblastoma|Epigenesis, Genetic|Hypoxia|Downregulation|Cell Line, Tumor|Cell Hypoxia|Response Elements|Lysine|SLC6A3 protein, human|Dopamine Plasma Membrane Transport Proteins 15 NDNF 29572178 Arch. Biochem. Biophys. 2018 10.1016/j.abb.2018.03.023 6 4 0 53 Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Brain-Derived Neurotrophic Factor|*Downregulation|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Line, Tumor|Cell Movement|Up-Regulation 15 PPP1R14C 29800458 J. Radiat. Res. 2018 PMC6054186 10.1093/jrr/rry038 1 5 0 90 Humans|*Idoxuridine|Iodine-123|*Iodine Radioisotopes|Gamma Rays|Linear Energy Transfer|Gene Expression Regulation|DNA Microarrays|DNA Damage|Gene Expression Profiling|*Biomarkers|Radiation Dosage|DNA|Gene Expression|Cell Line 15 PPP1R14C 29423094 Oncotarget 2018 PMC5790511 10.18632/oncotarget.22883 0 30 0 90 Humans|Male|AR protein, human|*Receptors, Androgen|Prostate Cancer|Androgens|Cell Proliferation|Prostate|RNAi|Cell Line, Tumor|Signal Transduction|Protein Phosphatase 1, Regulatory Subunit|Gene Expression Regulation, Neoplastic|Downregulation|Transcription Factors 15 RSRC1 30532555 Onco Targets Ther 2018 PMC6241732 10.2147/OTT.S177384 2 0 0 134 Humans|*Carcinoma, Non-Small-Cell Lung|*Biomarkers, Tumor|*Lung Cancer|Liquid Biopsy|Early Detection of Cancer|Positron Emission Tomography|Lung|Tomography, X-Ray Computed|*Platelet|Mutation|Survival Rate 15 RSRC1 29728651 Neuropsychopharmacology 2018 PMC6098070 10.1038/s41386-018-0078-9 6 0 0 134 *Depressive Disorder, Major|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Risk Factors 15 RSRC1 29653227 Gene 2018 10.1016/j.gene.2018.04.015 3 0 0 134 Child|Humans|Genome-Wide Association Study|Case-Control Studies|*Chinese|*Neuroblastoma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Allele|Gene Frequency|Genotype|Odds Ratio|CPZ protein, human|Carboxypeptidases|RSRC1 protein, human|Nuclear Proteins 15 RSRC1 29522154 Brain 2018 10.1093/brain/awy045 4 0 0 134 Child|Humans|Animals|Mice|IGFBP3 protein, human|*Insulin-Like Growth Factor Binding Protein 3|*Mutation|Intellectual Disability|*Downregulation|*RNA Splicing|Developmental Disabilities|Homozygote|Sequencing, Whole Exome|Nuclear Proteins|Hypotonia|Rett Syndrome|Methyl-CpG-Binding Protein 2|Alternative Splicing|Decay, Nonsense-Mediated mRNA|Phenotype|RSRC1 protein, human 15 RUSC2 30348779 Proc. Natl. Acad. Sci. U.S.A. 2018 PMC6233099 10.1073/pnas.1809969115 11 1 0 57 Animals|Humans|Drosophila Proteins|Drosophila melanogaster|*Mutations|Parkinson Disease|Dopaminergic Neurons|Disease Models, Animal|Exomes 15 RUSC2 30262884 Nat Commun 2018 PMC6160451 10.1038/s41467-018-06172-7 19 18 0 57 Humans|Proteomics|Autophagosomes|Autophagy-Related Proteins|*Autophagy|Membrane Proteins|Vesicular Transport Proteins|Protein Transport|trans Golgi Network|TYRP1 protein, human|*Membrane Glycoproteins|Endosomes|Cell Membrane|Adaptor Proteins, Signal Transducing|RUSC2 protein, human|Carrier Proteins|Atg9a protein, human|SERINC1 protein, human 15 SLC22A24 29703930 Sci Rep 2018 PMC5923232 10.1038/s41598-018-24967-y 5 2 0 1 Humans|*Whole Exome Sequencing|*Colon|Exomes|Mutations|Anorectal Anomalies|Open Reading Frames|Genes, Regulator|TSPAN32 protein, human|Tetraspanins 15 SMR3B 30239198 J. Am. Chem. Soc. 2018 10.1021/jacs.8b07877 2 0 0 14 *Proline|polyproline|Peptides|Proteins|Protein Structure, Secondary|Organoselenium Compounds|Acylation 15 SMR3B 29339256 Arch. Oral Biol. 2018 10.1016/j.archoralbio.2018.01.006 1 0 0 14 Humans|glutaminyl-arginyl-phenylalanyl-seryl-arginine|*Proline|*Salivary Proteins and Peptides|*Oligopeptides|Salivary Proline-Rich Proteins|Tandem Mass Spectrometry|Chromatography, Liquid|Amino Acid Sequence|Chromatography, High Pressure Liquid|Saliva|Proteomics|Proteome|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Protein Processing, Post-Translational 15 SSH2 30143211 Anal. Chim. Acta 2018 10.1016/j.aca.2018.05.045 2 0 0 99 *src Homology Domains|*Phosphorylation|Reproducibility of Results|Phosphotyrosine|Proteomics|Proteome|Peptides|Tyrosine 15 TBCK 30591081 Acta Neuropathol Commun 2018 PMC6307319 10.1186/s40478-018-0646-6 1 0 0 56 Humans|Child|*Neuronal Ceroid-Lipofuscinoses|*Lysosomal Storage Disease|*Homozygote|*Mutation|Lysosomes|Muscle Hypotonia|Facies|Intellectual Disability|Phenotype|Protein-Serine-Threonine Kinases|mTORC1|Neurons|Central Nervous System|TBCK protein, human 16 TBCK 30103036 Eur J Med Genet 2018 10.1016/j.ejmg.2018.08.004 0 1 0 56 Humans|*Muscle Hypotonia|*Facies|Neurodegenerative Diseases|*Psychomotor Disorders|Phenotype|Homozygote|Mutations|Intellectual Disability|Pedigree|Alleles|*Face|Sisters|Protein-Serine-Threonine Kinases|Brain Diseases|*Muscular Diseases|*Musculoskeletal Abnormalities|*Motor Neuron Disease|TBCK protein, human 16 TCFL5 30067948 Hum. Pathol. 2018 10.1016/j.humpath.2018.07.019 0 0 0 661 Humans|Adult|Male|DMRT1 protein|*Testis|Testicular Germ Cell Tumor|*Germ Cell Neoplasms|Testicular Neoplasms|Seminoma|*Transcription Factors|POU5F1 protein, human|*Octamer Transcription Factor-3|Sex Cord-Gonadal Stromal Tumors|Carcinoma, Embryonal|Seminiferous Tubules|Spermatogonia|Spermatocytes|Spermatogenesis|TYRP1 protein, human|*Membrane Glycoproteins|Biomarkers, Tumor 15 TP53I11 30376610 IUBMB Life 2018 10.1002/iub.1949 1 6 0 22 *AMP-Activated Protein Kinases|Epithelial-Mesenchymal Transition|Signal Transduction|Proto-Oncogene Proteins c-akt|*Extracellular Matrix|Snail Family Transcription Factors|TOR Serine-Threonine Kinases|Cadherins|Vimentin|Cell Movement|Gene Expression Regulation, Neoplastic|Phosphorylation|Cell Line, Tumor|Epithelial Cells|Antigens, CD 15 TP53I11 30241046 Biomed. Pharmacother. 2018 10.1016/j.biopha.2018.09.062 1 1 0 22 Humans|*Hep G2 Cells|Carcinoma, Hepatocellular|*Reactive Oxygen Species|Liver Neoplasms|*Mitochondria|*Apoptosis|Cell Line, Tumor|Liver 15 TUT1 30483311 Front Genet 2018 PMC6240794 10.3389/fgene.2018.00538 3 1 0 217 Humans|UTP-RNA uridylyltransferase|U6 small nuclear RNA|RNA, Small Nuclear|RNA Nucleotidyltransferases|Ribonucleoprotein, U4-U6 Small Nuclear|RNA Splicing|Spliceosomes|MicroRNAs|Nucleotidyltransferases|Crystallography, X-Ray|Models, Molecular 15 TUT1 30257214 Cell Rep 2018 10.1016/j.celrep.2018.08.077 4 5 0 217 Humans|Rats|Animals|*3' Untranslated Regions|*Rats, Wistar|RBM10 protein, human|*RNA-Binding Proteins|*RNA Splicing|*Cardiac Hypertrophy|RNA Precursors|mRNA|Polyadenylation|Alternative Splicing|Binding Sites|HEK293 Cells|Heart Failure|Star-PAP protein, human|Polynucleotide Adenylyltransferase 15 TUT1 30057901 Front Mol Biosci 2018 PMC6053540 10.3389/fmolb.2018.00061 7 24 0 217 Humans|Animals|TRF4-2 protein, human|RNA Nucleotidyltransferases|*Gene Expression Regulation|RNA Modifications, Post-Transcriptional|MicroRNAs|RNA Binding Protein|RNA Stability|Uridine|DNA-Binding Proteins|mRNA|U6 small nuclear RNA|RNA, Small Nuclear|Polynucleotide Adenylyltransferase|*RNA 3' End Processing|Non-Coding RNA|Base Sequence|HEK293 Cells|Nucleotidyltransferases 15 ZNF219 29450879 Clin. Genet. 2018 10.1111/cge.13239 5 0 0 67 Humans|*Microphthalmos|Anophthalmos|Exome|Mutation|Pedigree|Sequencing, Whole Exome|Sequencing, Next-Generation|Sequence Analysis, DNA|Alleles|CNKSR1 protein, human|Intracellular Signaling Peptides and Proteins 15 ZNF219 29379079 Sci Rep 2018 PMC5789009 10.1038/s41598-018-20177-8 6 5 0 67 Humans|Cattle|Animals|*INDEL Mutation|Promoter Regions, Genetic|Polymorphism, Genetic|Gene Expression Regulation|PAX7 Transcription Factor|Genetic Association Studies|*Gene Expression|Genotype|*Phenotypes|Luciferase|*Chinese|PAX7 protein, human 15 ZNF81 30559312 Cold Spring Harb Mol Case Stud 2018 PMC6318775 10.1101/mcs.a003285 3 0 0 22 Humans|Male|*Intellectual Disability|*Autistic Disorder|Autism Spectrum Disorder|Neurodevelopmental Disorders|*Multifactorial Inheritance|Whole Exome Sequencing|*Boys|*Sequencing, Whole Genome|Phenotype|Motor Skills Disorders|Mutation|Monozygotic Twins 15 ADAP2 28776093 Hum. Genet. 2017 10.1007/s00439-017-1832-5 3 0 0 62 Humans|Child, Preschool|*Neurofibromatosis 1|NF1 Microdeletion Syndrome|Neurofibromatoses|Chromosome Deletion|Genotype-Phenotype Correlations|Craniofacial Abnormalities|Intellectual Disability|Phenotype|Learning Disabilities|Genetic Predisposition to Disease|Gene Deletion|Allele|Array Comparative Genomic Hybridization|Chromosomes, Human, Pair 17|ADAP2 protein, human|GTPase-Activating Proteins|SUZ12 protein, human|Polycomb Repressive Complex 2 15 ADAP2 28706196 Sci Rep 2017 PMC5509740 10.1038/s41598-017-05588-3 7 26 0 62 *Guanine Nucleotide Exchange Factors|*Signal Transduction|GTPase-Activating Proteins|Small GTPases|Guanosine Triphosphate|Neurons|Postsynaptic Density 15 ANKLE1 28957321 PLoS Genet. 2017 PMC5619690 10.1371/journal.pgen.1006761 10 3 0 68 Humans|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Allele|Genetic Predisposition to Disease|Regulatory Regions|Linkage Disequilibrium|*Protein Binding|Quantitative Trait Loci|Chromatin|Transcription Factors|Genomics|Phenotypes 15 ANKLE1 28362817 PLoS Genet. 2017 PMC5391966 10.1371/journal.pgen.1006690 13 1 0 68 Humans|Female|Genome-Wide Association Study|*Quantitative Trait Loci|Genetic Predisposition to Disease|Linkage Disequilibrium|Polymorphism, Single Nucleotide|*Risk|*Ethnic Groups|Gene Expression|Cohort Studies|ACAP1 protein, human|GTPase-Activating Proteins|RCCD1 protein, human|Carrier Proteins|Membrane Proteins 15 ANKLE1 28146080 Int J Mol Sci 2017 PMC5343831 10.3390/ijms18020295 2 4 0 68 Humans|*Acitretin|*Whole Exome Sequencing|*Psoriasis|Keratolytic Agents|Single Nucleotide Polymorphisms 15 ARPP21 28395118 Genes Chromosomes Cancer 2017 10.1002/gcc.22464 10 0 0 59 RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|*Acute Lymphoblastic Leukemia|*Immunophenotyping|*B-Cell Leukemia|*Precursor Cells, B-Lymphoid|Oncogene Proteins, Fusion|*Leukemia, Lymphocytic, Chronic, B-Cell|In Situ Hybridization, Fluorescence|CD44 protein, human|*Hyaluronan Receptors 15 ARPP21 28222718 BMC Med 2017 PMC5320752 10.1186/s12916-017-0792-x 11 12 0 59 Adult|Humans|*Muscle Fibers, Skeletal|Myogenesis|*Epigenesis, Genetic|*Cell Differentiation|DNA Methylation|Muscle, Skeletal|Gene Expression Regulation, Developmental|*Obesity|Stem Cells 15 C2CD4A 28490609 Diabetes 2017 PMC5521867 10.2337/db16-1452 23 4 0 19 Humans|*Insulin Secretion|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Intravenous Glucose Tolerance Test|Blood Glucose|Insulin|Insulin-Secreting Cells|Transcription Factor 7-Like 2 Protein|Genotype|Genetic Predisposition to Disease|Alleles|Polymorphism, Single Nucleotide|Glucose|Genetic Variation|KCNQ1 Potassium Channel 15 CLUH 28975370 Cell. Mol. Life Sci. 2017 10.1007/s00018-017-2665-z 7 0 0 105 Adult|Humans|Infant, Newborn|*Oxidative Phosphorylation|*Mesenchymal Stem Cells|*Glycolysis|*Anaerobiosis|Umbilical Cord|Cell Differentiation|Energy Metabolism|Gestational Age|Mitochondria|Cells, Cultured|Bone Marrow 15 CLUH 28424233 J. Cell. Sci. 2017 10.1242/jcs.201616 0 0 0 105 Oxidative Phosphorylation|Mitochondria|Krebs Cycle|Energy Metabolism|Mitochondrial Dynamics|DNA, Mitochondrial|Adenosine Triphosphate|Oxidation-Reduction|Protein Biosynthesis|Fatty Acids|Glucose 15 CLUH 28188211 J. Cell Biol. 2017 PMC5350512 10.1083/jcb.201607019 13 4 0 105 *mRNA|*Mitochondria|Protein, Mitochondrial|RNA Binding Protein|Protein Biosynthesis|DNA, Mitochondrial|Adenosine Triphosphate|Gene Expression Regulation|Cytosol 15 CMTM1 28237839 Mol. Ther. 2017 PMC5383631 10.1016/j.ymthe.2017.02.004 23 0 0 8 Humans|Dogs|Animals|Child, Preschool|Tissue Distribution|*Myotubular Myopathy|myotubularin|Protein Tyrosine Phosphatases, Non-Receptor|*Gene Therapy|Adeno-Associated Virus|Muscle, Skeletal|Genetic Vectors|Disease Models, Animal|Phenotype|Mutations|Gait 15 CMTM1 28129775 World J Surg Oncol 2017 PMC5273821 10.1186/s12957-016-1094-z 3 2 0 8 Humans|Male|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Neoplasm Recurrence, Local|Neoadjuvant Therapy|Adenocarcinoma|Carcinoma, Squamous Cell|Neoplasm Staging|Prognosis|Antineoplastic Combined Chemotherapy Protocols|Biomarkers, Tumor|Lymphatic Metastasis|Cisplatin|Survival Rate|Platinum 15 DUSP11 28932105 Biomark Insights 2017 PMC5598794 10.1177/1177271917730557 4 2 0 83 Humans|*Alternative Splicing|5-((4-(5-(7,7-dimethyl-1,6-dioxaspiro(2.5)octan-5-yl)-3-methylpenta-2,4-dien-1-yl)cyclohexyl)amino)-5-oxopent-3-en-2-yl methylcarbamate|*Spiro Compounds|*Cyclohexylamines|RNA Precursors|RNA Splicing|Exons|Antineoplastic Agents|Cancer|RNA, Messenger 15 DUSP11 28621429 Int. J. Dev. Biol. 2017 10.1387/ijdb.160250ao 2 2 0 83 Animals|*Drosophila|*Ubiquitin|Drosophila Proteins|Drosophila melanogaster|*Immunity, Innate|Ubiquitin-Protein Ligases|Signal Transduction|NF-kappa B|degringolade protein, Drosophila 15 DUSP11 28296624 RNA Biol 2017 PMC5785229 10.1080/15476286.2017.1306169 8 6 0 83 Animals|*Non-Coding RNA|RNA Interference|Ribonuclease III|RNA-Induced Silencing Complex|miRNAs|Argonaute Proteins|DEAD-box RNA Helicases|RNA, Small Interfering|RNA, Viral|Gene Silencing|*Phosphoric Monoester Hydrolases|*Biochemical Phenomena|Protein Binding 15 FGGY 29220483 Endocrinology 2017 PMC5774244 10.1210/en.2017-00711 4 0 0 8 Pregnancy|Male|Female|Mice|Animals|bisphenol A|*DNA Methylation|Epigenesis, Genetic|*Prenatal Exposure Delayed Effects|bisphenol B|*Benzhydryl Compounds|*Phenols|Endocrine Disruptors|*Promoter Regions, Genetic|*Obesity|*Adipose Tissue, White|Body Weight|*Gonads|*Carbohydrate 15 FGGY 28394258 J. Clin. Invest. 2017 PMC5409098 10.1172/JCI84840 27 0 0 8 Genome-Wide Association Study|*Heart|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genetic Loci|Quantitative Trait, Heritable|Genotype 15 FOXRED1 28858979 J. Hypertens. 2017 10.1097/HJH.0000000000001529 0 4 0 26 Humans|Female|Pregnancy|*Trophoblasts|*Flavin-Adenine Dinucleotide|*Pyruvate Dehydrogenase (Lipoamide)-Phosphatase|Placentas|Pre-Eclampsia|*Apoptosis|*Mitochondria|Downregulation|MicroRNAs|Cell Line|Blotting, Western|*Oxidoreductases|Oxidative Stress|MIRN195 microRNA, human 16 gal3st1 28373486 J. Lipid Res. 2017 PMC5454501 10.1194/jlr.D076190 11 0 0 36 Animals|Galactosylceramides|Glucosylceramides|Chromatography, Thin Layer|*Mammals|*Bacteria 15 GREB1L 29261186 Genet. Med. 2017 10.1038/gim.2017.173 4 0 0 24 Hereditary renal agenesis|*Kidney|Renal Adysplasia|*Urogenital Abnormalities|*Kidney Diseases|Limb Deformities, Congenital|Anus, Imperforate|Trachea|Anal Canal|Esophageal Atresia|Esophagus|*Solitary Kidney|*Mutations|Spine|Abnormalities, Multiple|Heart Defects, Congenital|Phenotype|*Genomics 15 GREB1L 29194579 Clin. Genet. 2017 10.1111/cge.13185 6 0 0 24 Humans|Pregnancy|Female|*Whole Exome Sequencing|Nerve Tissue Proteins|Receptors, Immunologic|Hereditary renal agenesis|*Kidney Diseases|*Urinary Tract|*Prenatal Diagnosis|*Fetuses|Kidney|*Autopsy|Urogenital Abnormalities|Exome|Phenotypes|Neoplasm Proteins|Mutation 15 GREB1L 29100091 Am. J. Hum. Genet. 2017 PMC5673669 10.1016/j.ajhg.2017.09.026 6 0 0 24 Male|Child|Female|Mice|Humans|Animals|Hereditary renal agenesis|*Kidney Diseases|Renal Adysplasia|*Kidney|Urogenital Abnormalities|*Mutations|Exome|Urinary Tract|Whole Exome Sequencing|Heterozygote|Neoplasm Proteins|Knockout Mouse|Fetuses 15 GREB1L 29100090 Am. J. Hum. Genet. 2017 PMC5673636 10.1016/j.ajhg.2017.09.018 10 1 0 24 Humans|Mice|Child|Animals|*Exome|Renal Adysplasia|*Urogenital Abnormalities|Hereditary renal agenesis|*Kidney Diseases|*Kidney|*Urinary Tract|*Mutations|Phenotypes|Sequencing, Whole Exome|Homozygote|Pedigree|Vesico-Ureteral Reflux|Membrane Proteins|Zebrafish|Slit3 protein, mouse 15 GREB1L 28739660 Genetics 2017 PMC5586373 10.1534/genetics.117.1125 10 1 0 24 Humans|Hereditary renal agenesis|*Solitary Kidney|*Receptor, Retinoic Acid|*Kidney Diseases|*Kidney|Renal Adysplasia|*Urogenital Abnormalities|Urinary Tract|Mutation|Membrane Proteins|Neoplasm Proteins|Phenotype 15 IGSF10 28339086 Int. J. Oncol. 2017 10.3892/ijo.2017.3919 8 0 0 19 Humans|Female|*Whole Exome Sequencing|*Endometrial Cancer|Exome|Mutations|High-Throughput Nucleotide Sequencing|Genomics|Oncogenes|Sequence Analysis, DNA|PTEN protein, human|PTEN Phosphohydrolase|Asian Continental Ancestry Group|Taiwan|MOCOS protein, human|Sulfurtransferases 15 ILDR2 28785060 Sci Rep 2017 PMC5547134 10.1038/s41598-017-07530-z 0 20 0 19 Animals|*Splicing Factors|*RNA Precursors|Tight Junctions|*RNA Splicing|Deafness|Membrane Proteins|Mutations|Epithelial Cells|Cell Line|Cell Nucleus|*Biophysical Phenomena|Cultured Cells 15 ILDR2 28709640 Kidney Int. 2017 10.1016/j.kint.2017.04.022 17 0 0 19 Humans|Mice|Animals|*Genes, Essential|Endothelial Cells|*Cytoskeletons|Podocytes|Cytoskeletal Proteins|Adaptor Proteins, Signal Transducing|siRNA|SYNPO protein, human|Microfilament Proteins|Signal Transduction|Membrane Proteins|Downregulation|Cell Survival|Apoptosis|ARHGEF18 protein, human|Rho Guanine Nucleotide Exchange Factors|Mpp5 protein, mouse|Nucleoside-Phosphate Kinase 15 MMP27 28893231 BMC Cancer 2017 PMC5594496 10.1186/s12885-017-3625-6 2 1 0 4 Humans|Female|*Cystadenocarcinoma, Serous|*Carcinoma, Ovarian Epithelial|Neoplasms, Glandular and Epithelial|Ovarian Neoplasms|*Gene Fusions|Oncogene Proteins, Fusion|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Neoplasm Grading|Chromosome Aberrations|Transcriptomes|DPP9 protein, human|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases 15 MMP27 28100167 BMC Genomics 2017 PMC5242001 10.1186/s12864-017-3488-x 8 4 0 4 Female|Male|Humans|Animals|Swine|Chickens|*Sperm|*Reproduction|Fallopian Tubes|Semen|Fertilization|Oviducts|Fertility|*Mammals|Uterus|cDNA Microarrays|Ovulation|Cervix Uteri|Vagina|*Cell Communication|Body Fluids 15 NAA25 29233735 Int. J. Biochem. Cell Biol. 2017 10.1016/j.biocel.2017.12.004 2 5 0 77 Humans|Mice|Animals|*bcl-2-Associated X Protein|*Acetylation|*Mitochondria|Saccharomyces cerevisiae|*Post-Translational Modifications|Cytosol|Apoptosis|Protein Transport|Palmitoylation|Phosphorylation|Naa25 protein, mouse|N-Terminal Acetyltransferase B 15 NAA25 28380339 Structure 2017 10.1016/j.str.2017.03.003 14 0 0 77 *NatB N-Terminal Acetyltransferase|*Acetylation|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|*Protein Processing, Post-Translational|Substrate Specificity|Acetyltransferases|Active Site|Peptides|NatB protein, S cerevisiae 15 RSRC1 28640246 Genet. Med. 2017 10.1038/gim.2017.78 3 0 0 134 Humans|*Genome-Wide Association Study|Phenotype|Genome, Human|Genetic Association Studies|Genetic Predisposition to Disease|Genotype|Exome|Traits, Complex|Genomics|Genetic Variation|Saudi Arabia 15 RSRC1 28545128 PLoS Genet. 2017 PMC5456408 10.1371/journal.pgen.1006787 21 5 0 134 Child|Humans|Child, Preschool|Genome-Wide Association Study|carboxypeptidase Z|*Neuroblastoma|*Carboxypeptidases|MLF1 protein, human|Allele|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Nuclear Proteins|Case-Control Studies|Odds Ratio|Homozygote|Cohort Studies|CPZ protein, human 15 SMR3B 28282514 Arch. Oral Biol. 2017 10.1016/j.archoralbio.2017.03.001 6 0 0 14 *Proteomics|*Dental Arch|*Dental Pellicle|Proteome 15 TBCK 29283439 Ann. Neurol. 2017 PMC5876123 10.1002/ana.25130 3 3 0 56 Humans|*Homozygote|*Autophagy|*Mutation|Protein-Serine-Threonine Kinases|Lysosomes|TOR Serine-Threonine Kinases|Mechanistic Target of Rapamycin Complex 1|Signal Transduction|Intellectual Disability|Encephalopathy|TBCK protein, human 16 TBCK 28708278 Clin. Genet. 2017 10.1111/cge.13101 14 0 0 56 Humans|*Whole Exome Sequencing|Inherited Peripheral Neuropathy|Charcot Marie Tooth Disease|High-Throughput Nucleotide Sequencing|Pedigree|*Cohort Studies|Mutation|KIF1A protein, human|Kinesin|TBCK protein, human|Protein-Serine-Threonine Kinases 16 TBCK 28422154 Sci Rep 2017 PMC5396199 10.1038/srep46539 8 17 0 56 Female|Swine|Animals|Genome-Wide Association Study|*Lipid Metabolism|Phosphatidylinositol 3-Kinases|*Networks, Gene|Quantitative Trait Loci|Meat|Phenotype|*Liver|Fatty Acids|Genotype|FABP1 protein, human|Fatty Acid-Binding Proteins|Adipose Tissue|Polymorphism, Single Nucleotide|Transcriptome|Muscle, Skeletal 16 TUT1 29032201 Biochem. Biophys. Res. Commun. 2017 10.1016/j.bbrc.2017.10.049 1 4 0 217 *Retinitis Pigmentosa|*Ubiquitination|*Cell Nucleolus|Genes, Dominant|Mutations|Ubiquitin|Pedigree|Autoantigens 15 TUT1 28589955 Nat Commun 2017 PMC5467268 10.1038/ncomms15788 10 16 0 217 Humans|U6 small nuclear RNA|UTP-RNA uridylyltransferase|*RNA, Small Nuclear|*RNA Nucleotidyltransferases|Ribonucleoprotein, U4-U6 Small Nuclear|RNA Splicing|Spliceosomes|Nucleic Acid Conformation|Base Sequence|Binding Site 15 TUT1 28315317 Anal. Biochem. 2017 PMC5490990 10.1016/j.ab.2017.03.009 0 3 0 217 Humans|*Chondrocytes|Aggrecans|Cartilage, Articular|Collagen Type II|*Transfections|mRNA|Osteoarthritis|siRNA|Cells, Cultured|Gene Expression Regulation 15 ZBTB7C 28571744 Biochim Biophys Acta Gene Regul Mech 2017 10.1016/j.bbagrm.2017.05.005 0 12 0 57 Humans|*Glutamine|*Cell Proliferation|Glutaminase|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|*Cancer|STAT1 protein, human|STAT1 Transcription Factor|Intracellular Signaling Peptides and Proteins|Promoter Regions, Genetic|HEK293 Cells|Gene Expression Regulation|ZBTB7C protein, human|Proteins 15 ZNF219 28782835 J. Cell. Biochem. 2017 10.1002/jcb.26328 3 1 0 67 *RNA, Long Noncoding|*Cachexia|MIRN1224 microRNA, human|MicroRNAs|Gene Modules|MIRN600 microRNA, human|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|RNA, Messenger|Wnt Signaling Pathway|Cell Line, Tumor 15 ADAP2 27956705 Mol. Cell. Biol. 2016 PMC5335504 10.1128/MCB.00537-16 4 2 0 62 Humans|DDX58 protein, human|*DEAD Box Protein 58|IRF3 protein, human|Interferon Regulatory Factor 3|*Signal Transduction|Type I Interferon|Phosphorylation|Adaptor Proteins, Signal Transducing|Protein-Serine-Threonine Kinases|Sendai virus|Protein Binding|NF-kappa B|DEAD-box RNA Helicases|*Protein Domain|Gene Expression Regulation|Immunity, Innate|HEK293 Cells|ADAP2 protein, human 15 AKIRIN1 27590857 Int. J. Biochem. Cell Biol. 2016 10.1016/j.biocel.2016.08.032 3 5 0 132 Animals|*Ribosomal Protein S6 Kinases, 70-kDa|*Ducks|MTOR protein, human|Mammalian Target of Rapamycin|*Signal Transduction|*Myoblasts|*Cell Differentiation|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Myotube|Rapamycin|Cell Cycle Checkpoints|Myogenic Regulatory Factors|*Mammals|Cell Proliferation 15 ANKLE1 27601076 Nat Commun 2016 PMC5023955 10.1038/ncomms12675 22 3 1 68 Humans|Female|*Alleles|BRCA1 protein, human|BRCA1 Protein|SNPs|Genetic Predisposition to Disease|Genome-Wide Association Study|Ovarian Cancer|Genotype|*Ovary|Cystadenocarcinoma, Serous|Chromosome Mapping|Promoter Regions, Genetic|Case-Control Studies|European Continental Ancestry Group 15 ANKLE1 27245214 BMC Cell Biol. 2016 PMC4888674 10.1186/s12860-016-0102-z 1 11 1 68 Animals|*Active Transport, Cell Nucleus|*Ankyrin Repeat|*Endonucleases|*Cytoplasm|Cell Nucleus|Nuclear Localization Signals|Karyopherins|*Cytosol|DNA-Binding Proteins|Amino Acid Sequence|Cell Cycle|Cell Line 15 ANKLE1 27010503 PLoS ONE 2016 PMC4807109 10.1371/journal.pone.0152278 3 3 1 68 Mice|Animals|*Ankyrin Repeat|*Endonucleases|Hematopoietic Stem Cells|DNA Repair|DNA Damage|Bone Marrow|Spleen|Erythropoiesis|Cell Differentiation|ANKLE1 protein, mouse 15 ARPP21 27462267 Front Aging Neurosci 2016 PMC4941795 10.3389/fnagi.2016.00171 3 14 1 59 Humans|*Apo E-4|*Alzheimer Disease|*Heterozygote|Apolipoproteins E|Gene Frequency|Genotype|Alleles|Polymorphism, Genetic|Genetic Predisposition to Disease|Parkinson Disease|Risk Factors|Apo E-3|Xpo4 protein, human|Karyopherins|RASD2 protein, human|GTP-Binding Proteins|RIN1 protein, human|Intracellular Signaling Peptides and Proteins 15 C2CD4A 27329800 Am. J. Physiol. Endocrinol. Metab. 2016 PMC5005967 10.1152/ajpendo.00074.2016 5 10 1 19 Male|Female|Mice|Humans|Animals|*Glucose Intolerance|*Diabetes Mellitus, Type 2|Insulin Secretion|Insulin-Secreting Cells|Insulin|Glucagon|Islets of Langerhans|Glucose|Mice, Knockout|Pancreas|Single Nucleotide Polymorphisms|VPS13C protein, human|Proteins 15 CLUH 27573102 Nat Microbiol 2016 10.1038/nmicrobiol.2016.62 5 2 0 105 *Influenza Viruses|Export, Nuclear|Ribonucleoprotein|RNA, Viral|Viral Proteins|Influenza A virus|Cytoplasm|Viral Matrix Proteins|Virus Replication|Cell Nucleus|Protein Transport 15 CLUH 26834020 Biol Open 2016 PMC4823986 10.1242/bio.015313 0 16 1 105 Humans|*Mitochondrial Membranes|*Ribonucleoprotein|*Ribosome|Mitochondria|parkin protein|Ubiquitin-Protein Ligases|Mitochondrial Proteins|Mitochondrial Membrane Transport Proteins|Cell Nucleus|Protein Transport|Carrier Proteins|mitochondrial messenger RNA|mRNA|RNA, Mitochondrial 15 CMTM1 27466507 Anticancer Res. 2016 6 0 0 8 *Carcinoma, Adenoid Cystic|Salivary Gland Neoplasms|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Movement|Cell Line, Tumor|*Chemokines|Lung Neoplasms 15 CMTM1 27356683 Asian Pac. J. Cancer Prev. 2016 4 0 0 8 Male|Humans|MARVEL Domain-Containing Proteins|Chemokines|Tumors|*Protein Domains|*Family Member 15 DUSP11 27798849 Genes Dev. 2016 PMC5066614 10.1101/gad.282616.116 15 1 0 83 Animals|*Argonaute Proteins|*MicroRNAs|Caenorhabditis elegans|DICER1 protein, human|Ribonuclease III|siRNA|RNAi|DEAD-box RNA Helicases|*Noncoding RNA|RNA, Viral|RNA Polymerase III|RNA triphosphatase|Acid Anhydride Hydrolases|Host-Pathogen Interactions 15 FGGY 27909055 J. Biol. Chem. 2016 PMC5247636 10.1074/jbc.M116.760744 4 0 0 8 Humans|Animals|D-ribulokinase|Saccharomyces cerevisiae|*Budding Yeast|HEK293 Cells|*Phosphotransferases (Alcohol Group Acceptor)|ribulokinase|ribulose|Pentoses|Saccharomyces cerevisiae Proteins|Ribitol|Substrate Specificity|*Mammals|Phosphorylation 15 FGGY 27223615 PLoS ONE 2016 PMC4880283 10.1371/journal.pone.0156067 0 1 1 8 *Arabidopsis|*Synechococcus|*Sugar|Synechococcus elongatus|xylulokinase|Phosphotransferases (Alcohol Group Acceptor)|ribulokinase|Arabidopsis Proteins|Crystallography, X-Ray|Amino Acid Sequence|Catalytic Domain|ribulose|Pentoses|Models, Molecular|Phosphorylation 15 FIZ1 27276561 N. Engl. J. Med. 2016 PMC4979995 10.1056/NEJMoa1516192 591 0 2 41 *Leukemia, Myeloid, Acute|*Prognosis|Isocitrate Dehydrogenase|DNA Mutational Analysis|Mutation|*Genomics|Kaplan-Meier Estimate|Nuclear Proteins 15 FOXRED1 27904784 Am J Cancer Res 2016 PMC5126286 0 0 0 26 Humans|*Colorectal Cancers|Immunohistochemistry|Lymphatic Metastasis|Biomarkers, Tumor|Electron Transport Complex I|*Colonic Neoplasms|Survival Rate|Prognosis|FOXRED1 protein, human|Molecular Chaperones 16 FOXRED1 27215383 Mol. Cell. Biol. 2016 PMC4968213 10.1128/MCB.00066-16 7 0 0 26 Humans|Animals|*Electron Transport Complex I|*Oxidative Phosphorylation|*Flavin-Adenine Dinucleotide|*Oxidoreductases|*Mutation|Homozygote|Mitochondrial Proteins|Molecular Chaperones|Mitochondria|Missense Mutation|FOXRED1 protein, human 16 FUBP3 27291656 Proteomics 2016 10.1002/pmic.201600098 2 0 0 105 *5' Untranslated Regions|*Enterovirus|Chromatography, Liquid|Tandem Mass Spectrometry|*Virus Replication|Enterovirus A, Human|Enterovirus Infections|RNA, Viral|Genome, Viral|Protein Biosynthesis|Cell Line|Protein Binding|Asia 15 FUBP3 27183999 J. Appl. Genet. 2016 10.1007/s13353-016-0351-8 1 0 0 105 Swine|Animals|*Genome-Wide Association Study|Quantitative Trait Loci|*Breeding|Mapping, Linkage|Sus scrofa|Genotype|Phenotype|Polymorphism, Single Nucleotide|Meat|Genomics 15 FUBP3 27134767 Brain Behav 2016 PMC4842934 10.1002/brb3.462 8 3 1 105 Genome-Wide Association Study|*Smoking|Tobacco Use Disorder|Genetic Predisposition to Disease|*Genome|*Tobacco Smoking|Polymorphism, Single Nucleotide|Genotype|*Disease Progression 15 FUBP3 27094516 BMC Genet. 2016 PMC4837538 10.1186/s12863-016-0368-3 6 5 1 105 Swine|Animals|*Genome-Wide Association Study|*Haplotypes|*Single Nucleotide Polymorphism|Quantitative Trait Loci|*Phenotype|*Meat|Genotype|Sus scrofa|Pedigree 15 FUBP3 26813465 Eur Rev Med Pharmacol Sci 2016 0 11 0 105 Rats|Animals|*Propofol|*Ketamine|Anesthetics, Intravenous|Hippocampus|Rats, Sprague-Dawley|*Brain Injury|Cognitive Function 15 gal3st1 26872740 BMC Genet. 2016 PMC4752738 10.1186/s12863-016-0351-z 6 0 1 36 Humans|*Whole Exome Sequencing|*Exome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pedigree|Sequence Analysis, DNA|Gastric Cancer|*Stomach|Colorectal Cancer|*Rectal Cancer 15 GRID2IP 27695129 PLoS ONE 2016 PMC5047451 10.1371/journal.pone.0164067 10 3 1 15 Female|Pregnancy|Animals|Humans|*Phylogeny|*Formins|Drosophila melanogaster|Microfilament Proteins|Actin Cytoskeleton|*Wings, Animal|Fetal Proteins|Protein Structure, Tertiary|Nuclear Proteins|Isoforms|DAAM protein, Drosophila|Drosophila Proteins|Adaptor Proteins, Signal Transducing 15 IGSF10 27659016 Neoplasia 2016 PMC5031903 10.1016/j.neo.2016.07.008 4 5 1 19 Humans|endothelial PAS domain-containing protein 1|*Paragangliomas|Basic Helix-Loop-Helix Transcription Factors|Pheochromocytoma|*Mutation|Polycythemia|Adrenal Gland Neoplasms|Somatostatinoma|Genotype|Genes, Regulator|Pancreatic Neoplasms 15 IGSF10 27137492 EMBO Mol Med 2016 PMC4888853 10.15252/emmm.201606250 20 9 1 19 Humans|Animals|Female|Adolescent|gonadotropin-releasing hormone-III|*Gonadotropin Releasing Hormone|Hypogonadism|Hypothalamus|*Mutations|Pyrrolidonecarboxylic Acid|*Cell Movement|Zebrafish|Neurons|mRNA|*Neurogenesis 15 IGSF10 26872740 BMC Genet. 2016 PMC4752738 10.1186/s12863-016-0351-z 6 0 1 19 Humans|*Whole Exome Sequencing|*Exome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pedigree|Sequence Analysis, DNA|Gastric Cancer|*Stomach|Colorectal Cancer|*Rectal Cancer 15 ILDR2 27353377 Biochem. 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Commun. 2016 10.1016/j.bbrc.2016.06.124 5 12 0 19 Mice|Animals|*Carrier Proteins|*Gene Expression|Membrane Proteins|Homeodomain Proteins|Basic Helix-Loop-Helix Transcription Factors|Lipid Metabolism|Livers|Promoter Regions, Genetic|Cell Nucleus|Endoplasmic Reticulum|Homeostasis|Hes1 protein, mouse|Transcription Factor HES-1|ILDR2 protein, mouse 15 ILDR2 27195292 Biomed Res Int 2016 PMC4852330 10.1155/2016/6137541 5 0 1 19 Humans|Animals|Mice|*Tight Junctions|Epithelial Cell|*Ear, Inner|Tricellulin|Hearing|Claudins|Mutations|ILDR1 protein, human|Receptors, Cell Surface|Ildr1 protein, mouse 15 ILDR2 27034888 Parkinsons Dis 2016 PMC4791501 10.1155/2016/4686185 4 42 1 19 Animals|Mice|*Organelle Biogenesis|*Arginine|Proteomics|alpha Synuclein|Parkinson Disease 7, Autosomal Recessive Early-Onset|Parkinson Disease|*Brain|PARK7 protein, human|Protein Deglycase DJ-1|Mesencephalon|Dopamine|Protein Kinases|Synaptic Plasticity|Mitochondria|Phenotypes|Crtc1 protein, mouse|Transcription Factors 15 LINC00324 27373735 Brief. Bioinformatics 2016 10.1093/bib/bbw053 67 0 0 2 *RNA, Long Noncoding|*miRNA|*RNAs, Circular|RNA, Messenger|Bioinformatics|Gene Expression Profiling|Gene Expression Regulation 15 LINC00324 26780889 Sci Rep 2016 PMC4726092 10.1038/srep19429 27 1 1 2 Humans|HDL Cholesterol|*Hispanics|Triglycerides|LDL Cholesterol|Genome-Wide Association Study|Linkage Disequilibrium|*Lipids|SNPs|Gene Frequency|European Continental Ancestry Group|*Phenotype|Alleles|Genotype|Lipid Metabolism|Mexico|Kank2 protein, human|Carrier Proteins|Tumor Suppressor Proteins 15 MMP27 27334288 Cancer Med 2016 PMC5055182 10.1002/cam4.796 1 7 1 4 Humans|*Polymorphism, Single Nucleotide|*Vascular Endothelial Growth Factor A|*Colorectal Cancer|*Vascular Endothelial Growth Factors|Neovascularization, Pathologic|Genotypes|Prognosis|Linkage Disequilibrium|MMP8 protein, human|Matrix Metalloproteinase 8|Cohort Studies|*Colonic Neoplasms 15 NAA25 27602548 Pharmacogenet. Genomics 2016 10.1097/FPC.0000000000000242 0 0 0 77 Humans|*Coronary Artery Disease|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|*Chromosome 1|Alleles|Haplotypes|Genotype|Case-Control Studies|Risk Factors|*Chromosome Structures 15 PFN3 27241791 Genomics 2016 PMC4996343 10.1016/j.ygeno.2016.05.004 6 1 1 11 Humans|Male|Mice|Animals|Phylogeny|RNA, Antisense|mRNA|Transcription, Genetic|Zebrafish|Alternative Splicing|Testis|Evolution, Molecular 15 PFN3 27185630 Gene 2016 10.1016/j.gene.2016.05.023 3 3 0 11 Male|Rats|Animals|*Profilins|*Isoforms|*Protein Structure, Secondary|Microfilament Proteins|Actins|Amino Acid Sequence|Testis|mRNA|Gene Expression Regulation 15 PPP1R14C 27333042 EBioMedicine 2016 PMC4972523 10.1016/j.ebiom.2016.05.028 6 60 1 90 Mice|Animals|*Parathyroid Hormone|Carbon-14|*Carbon Radioisotopes|*Protein Phosphatase 1|*Osteoblasts|Parathyroid Hormone Receptor Type 1|*Signal Transduction|Bone Formation|Bone Remodeling|Bone and Bones|Cell Differentiation|Cells, Cultured|Carrier Proteins 15 RSRC1 26881967 EMBO Mol Med 2016 PMC4772951 10.15252/emmm.201505495 30 16 1 134 Humans|Mice|Animals|*Glioblastoma|Brain Neoplasms|Glioma|miRNA|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Xenograft Model Antitumor Assays|Oligonucleotides, Antisense|Cell Cycle|Brain 15 RUSC2 27633991 Development 2016 PMC5117142 10.1242/dev.138917 3 7 0 57 Animals|*Hedgehog Proteins|GLI1 protein, human|Gli Protein|*Signal Transduction|*Transcription Factors|Repressor Proteins|Kruppel-Like Transcription Factors|Cilia|Xenopus laevis|Sufu protein, Xenopus|Xenopus Proteins|Intracellular Signaling Peptides and Proteins 15 RUSC2 27612186 Dev Med Child Neurol 2016 10.1111/dmcn.13250 3 0 0 57 Humans|*Microcephaly|*Intellectual Disability|*Mutation|Exome|Homozygote|Muscle Hypotonia|Epilepsy|Pedigree|Brain Diseases|Nonsense Mutations|Brain|RUSC2 protein, human|Carrier Proteins 15 RUSC2 27238570 Cancer Lett. 2016 10.1016/j.canlet.2016.05.027 9 4 0 57 *Lung Cancer|Carcinoma, Non-Small-Cell Lung|*Epidermal Growth Factor|*Cell Migration|Signal Transduction|ErbB Receptors|Phosphorylation|PXN protein, human|Paxillin|Cell Line, Tumor|RNA Interference 15 SLC25A31 27127921 Mol. Reprod. Dev. 2016 10.1002/mrd.22651 5 0 0 20 Female|Cattle|Animals|*Oocytes|*Ovarian Follicle|Oogenesis|*Transcriptome Analysis|Fertilization in Vitro|Meiosis|Embryonic Development|Blastocyst|Oligonucleotide Array Sequence Analysis|Embryo, Mammalian|mRNA|Gene Expression Regulation, Developmental|Chromatin Assembly and Disassembly|Transcriptomes|Cell Nucleus 15 SLC25A31 26729753 Hypertension 2016 PMC4752391 10.1161/HYPERTENSIONAHA.115.06345 15 10 0 20 Humans|*African Americans|*Blood Pressure|*Pharmacogenetics|Genome-Wide Association Study|*Hypertension|Antihypertensive Agents|Atenolol|Hydrochlorothiazide|*Pharmacogenomic Analysis|European Continental Ancestry Group|Pharmacogenomic Variants|Metoprolol|Polymorphism, Single Nucleotide|Systole|Genotype 15 SSH2 27880036 Proteomics 2016 10.1002/pmic.201600360 4 0 0 99 Humans|*Phosphotyrosine|*src Homology Domains|*Proteome|HeLa Cells|*Mass Spectrometry|*Chromatography, Affinity|TYRP1 protein, human|*Membrane Glycoproteins|Proteomics|Sequences, Amino Acid|Protein Binding|Signal Transduction|Cell Line, Tumor|Peptides 15 SSH2 26748257 Behav. 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Genet. 2016 PMC4833196 10.1016/j.ajhg.2016.01.016 0 0 0 56 *GTPase Activating Protein|*Mutations|*Brain Diseases|Muscle Hypotonia|Homozygote|Phenotype|Intellectual Disability|Pedigree|Protein-Serine-Threonine Kinases|Signal Transduction|Nervous System Malformations|*Syndromes|Seizures 16 TBCK 27040691 Am. J. Hum. Genet. 2016 PMC4833465 10.1016/j.ajhg.2016.03.016 12 4 0 56 Child|Humans|*Muscle Hypotonia|*Intellectual Disability|*Mutations|MTOR protein, human|Mammalian Target of Rapamycin|*Syndrome|Phenotype|Protein-Serine-Threonine Kinases|Brain Diseases|Signal Transduction|Seizures|*Recognition, Psychology|TBCK protein, human 16 TUT1 27455002 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2016 10.3760/cma.j.issn.1003-9406.2016.04.011 1 0 0 217 Humans|Male|Child|*Autism Spectrum Disorder|*Mutation|Genetic Predisposition to Disease|Mutation, Missense|DIAPH3 protein, human|Formins 15 TUT1 26809675 Nucleic Acids Res. 2016 PMC4824107 10.1093/nar/gkw040 34 10 1 217 Mice|Animals|*RNA, Micro|Proteomics|*RNA Degradation|AGO2 protein, human|Argonaute Proteins|RNA, Messenger|RNA-Induced Silencing Complex|Exoribonucleases|Transfection|Gene Expression|Dis3l2 protein, mouse 15 ZBTB7C 27646874 Biochim. Biophys. Acta 2016 10.1016/j.bbagrm.2016.09.004 1 19 0 57 Activator Protein-1|*Matrix Metalloproteinases|Transcriptional Activation|Phosphorylation|Proto-Oncogene Proteins c-jun|Transcription, Genetic|Genes, jun|Signal Transduction|Promoter Regions, Genetic|EP300 protein, human|E1A-Associated p300 Protein|JNK Mitogen-Activated Protein Kinases|Cell Proliferation|Matrix Metalloproteinase 9|NCOR1 protein, human|Nuclear Receptor Co-Repressor 1|Upregulation 15 ADAP2 26372645 PLoS Pathog. 2015 PMC4570769 10.1371/journal.ppat.1005150 11 24 1 62 Humans|*Virus Internalization|*Interferon|ADP-ribosylation factor 6|ADP-Ribosylation Factors|*RNA Virus|Vesiculovirus|*Antiviral Agents|GTPase Activating Protein|Virus Replication|Sendai virus|Phosphatidylinositol|Cell Membrane|HEK293 Cells|Cytoplasm|RNA, Small Interfering|STAT1 protein, human|STAT1 Transcription Factor|ADAP2 protein, human 15 ADAP2 25751262 PLoS ONE 2015 PMC4353720 10.1371/journal.pone.0121441 11 69 3 62 Guanine Nucleotide Exchange Factors|GTPase-Activating Proteins|Signal Transduction|Guanine Nucleotide Dissociation Inhibitors|Generalized Epilepsy with Febrile Seizures Plus|*Epilepsy, Generalized|*Seizures, Febrile|rhoGDI|*Transcription Factors|Small G-Proteins|Phosphorylation|Cell Proliferation|Superoxide Dismutase 15 AKIRIN1 25912355 Dev. 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Immunol. 2015 10.1016/j.dci.2015.04.010 2 0 0 132 Animals|*Genes, rel|*Croaker|*Genome|Conserved Synteny|Sequence Alignment|Fish Proteins|Amino Acid Sequence|Phylogeny|Evolution, Molecular|Base Sequence|Introns|Genomics|Gene Expression Profiling|Exons|Nuclear Proteins 15 ANKLE1 26031516 J Transl Med 2015 PMC4450850 10.1186/s12967-015-0525-x 11 7 1 68 Sjogren's Syndrome|Autoimmunity|Autoimmune Diseases|Genomics|Genetic Predisposition to Disease|Phenotype 15 ARPP21 25972145 Stem Cells Transl Med 2015 PMC4479615 10.5966/sctm.2014-0083 7 0 1 59 Humans|*GABAergic Neurons|*Corpus Striatum|*Neural Stem Cells|Huntington Disease|Dopamine and cAMP-Regulated Phosphoprotein 32|Huntingtin Protein|Cell Differentiation|Calbindin|Nerve Tissue Proteins|Glutamate|Interneurons|Nuclear Proteins|Glutamate Agonists 15 CMTM1 25931111 Genes Chromosomes Cancer 2015 10.1002/gcc.22255 5 2 2 8 Humans|*Glioblastoma|MARVEL Domain-Containing Proteins|Cell Proliferation|Oncogenesis|Chemokines|Signal Transduction|Downregulation|CMTM3 protein, human 15 ERGIC2 25999661 Dis. Markers 2015 PMC4426656 10.1155/2015/824304 5 3 0 139 Male|Humans|*Cisplatin|GPC5 protein, human|*Glypicans|*C-Reactive Protein|Case-Control Studies|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|*Lung Cancer|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|Gene Frequency|Haplotypes|Allele|Risk Factors|GKN1 protein, human|Peptide Hormones 15 FOXRED1 26235939 Mitochondrion 2015 10.1016/j.mito.2015.07.009 0 1 0 26 *NAD|*Ubiquinone|*Electron Transport Complex I|Leigh Syndrome|Molecular Chaperones|Mitochondria|*Metabolism, Inborn Errors|Mutations|Glutathione 16 FOXRED1 25765152 Mitochondrion 2015 10.1016/j.mito.2015.02.008 3 4 0 26 *Flavin-Adenine Dinucleotide|*NAD|*Ubiquinone|*Electron Transport Complex I|*Oxidoreductases|Binding Site|Amino Acid Sequence|*Structural Model|Sulfur 16 FOXRED1 25681241 Biochim. Biophys. Acta 2015 10.1016/j.bbabio.2015.01.014 8 0 0 26 Humans|*Flavin-Adenine Dinucleotide|*NAD|*Ubiquinone|Phylogeny|*Electron Transport Complex I|*Oxidoreductases|FOXRED1 protein, human|Molecular Chaperones|Leigh Syndrome|Respiratory Chains|Mitochondria|*Metabolism, Inborn Errors 16 FOXRED1 25678554 Hum. Mol. Genet. 2015 10.1093/hmg/ddv058 17 1 1 26 Humans|*Electron Transport|HEK293 Cells|*Mitochondrial Membranes|*Mitochondria|Electron Transport Complex I|Mitochondrial Proteins|Molecular Chaperones|DNA, Mitochondrial|Mutations|FOXRED1 protein, human 16 GRID2IP 25893121 Case Rep Genet 2015 PMC4393924 10.1155/2015/212436 1 0 0 15 Humans|Male|Child|Child, Preschool|*Autistic Disorder|Chromosome 7, trisomy 7p|Trisomy|Chromosome Duplication|Craniofacial Abnormalities|Abnormalities, Multiple|Speech Delay|Chromosomal Abnormalities|Phenotype|Syndrome|*Chromosome Structures|Chromosomes, Human, Pair 7|FSCN1 protein, human|Carrier Proteins|Microfilament Proteins|AIMP2 protein, human|Nuclear Proteins|EIF2AK1 protein, human 15 NAA25 26600389 PLoS ONE 2015 PMC4658088 10.1371/journal.pone.0142943 1 43 1 77 Animals|Humans|*mTORC2|*Actins|HEK293 Cells|HeLa Cells|TOR Serine-Threonine Kinases|Rapamycin-Insensitive Companion of mTOR Protein|Multiprotein Complexes|Phosphorylation|Proto-Oncogene Proteins c-akt|Carrier Proteins|Protein Binding|Actin Cytoskeleton|Cell Proliferation|Cell Cycle|Cell Movement|Protein Processing, Post-Translational|RICTOR protein, human 15 NAA25 25768301 PLoS Genet. 2015 PMC4359108 10.1371/journal.pgen.1005029 9 30 2 77 Animals|Humans|*Caenorhabditis elegans|*Acetyl-CoA Hydrolase|*Acetyl Coenzyme A|*Meiosis|Caenorhabditis elegans Proteins|DNA Breaks, Double-Stranded|Crossing Over, Genetic|Chromatin|Chromosome Segregation|Histones|X Chromosome|Acetylation|xnd-1 protein, C elegans 15 NDNF 26183719 Mol. Cell Proteomics 2015 PMC4597141 10.1074/mcp.M115.049312 6 0 2 53 Animals|Rats|Humans|*Fetal Blood|*Stem Cells, Somatic|Stem Cell|Cell Differentiation|Neurons|Cells, Cultured|Axons|Stem Cell Transplantation|*Phenotype|Neurogenesis|Injury, Spinal Cord|Cell Motility 15 NDNF 25654972 Circ Heart Fail 2015 10.1161/CIRCHEARTFAILURE.114.001647 9 1 0 53 Animals|*Ventricular Remodeling|*Myocardial Infarction|enovin|*Nerve Growth Factors|NTF3 protein, human|Ventricular Dysfunction, Left|Myocytes, Cardiac|Proto-Oncogene Proteins c-akt|Neovascularization, Physiologic|Heart Failure|Genetic Therapy|Apoptosis|Fibrosis|Disease Models, Animal|*Neurons 15 PPP1R14C 25689671 Reprod. Fertil. Dev. 2015 10.1071/RD14353 1 0 0 90 Cattle|Animals|Female|Nerve Tissue Proteins|Receptors, Immunologic|*Oocyte|Oogenesis|Cleavage Stage, Ovum|Blastocyst|Embryonic Development|Fertility|Fertilization in Vitro|Gene Expression Regulation, Developmental|Quantitative Trait Loci|RNA, Messenger|*Phenotype 15 RSRC1 25937118 FEBS Lett. 2015 10.1016/j.febslet.2015.04.035 3 6 0 134 Humans|*Sumoylation|*Receptors, Estrogen|Protein Inhibitors of Activated STAT|Transcription Factor|Estrogen Receptor beta|Transcription, Genetic|Signal Transduction|Protein Binding|Gene Expression Regulation|Promoter Regions, Genetic|Cell Line, Tumor|HEK293 Cells|Estrogens|RSRC1 protein, human|Nuclear Proteins 15 RUSC2 25800845 Methods Mol. Biol. 2015 10.1007/978-1-4939-2569-8_18 0 1 1 57 Rats|Humans|Mice|Animals|rab GTP-Binding Proteins|GTPase-Activating Proteins|Protein Transport|Cytokinesis|PC12 Cells|Neurites|Cell Migration|Guanosine Triphosphate|RUSC2 protein, human|Carrier Proteins|RAB35 protein, human|Rab35 protein, mouse 15 SLC22A24 26269671 World J. Gastroenterol. 2015 PMC4528024 10.3748/wjg.v21.i29.8817 0 0 0 1 Rats|Animals|*Kidney|Organic Anion Transporters, Sodium-Dependent|Dicarboxylic Acid Transporters|*Membrane Transport Proteins|Symporters|Citrates|Citrate|Cholestasis, Extrahepatic|*Biliary Tract|OAT5 protein, rat 15 SLC22A24 26230185 Chem. Res. 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Physiol. 2015 PMC4386001 10.1152/ajpregu.00153.2014 1 0 0 14 Male|Rats|Humans|Mice|Animals|*Spermatids|*Salivary Glands|Salivary Proteins and Peptides|Amino Acid Sequence|*Anti-Inflammatory Agents|Protein Precursors|Homologous Sequences|calcium-binding protein spermatid-specific 1, human|*Calcium-Binding Proteins|Cloning, Molecular|Multigene Family|Lung|CABS1 protein, mouse 15 SSH2 25580081 Eur J Inorg Chem 2015 PMC4286256 10.1002/ejic.201402082 7 9 1 99 *Kinetics|*Hydrogen Sulfide|*Water|Hydrogen-Ion Concentration|Thermodynamics 15 SSH2 25568344 Mol. Biol. Cell 2015 PMC4342024 10.1091/mbc.E14-05-0982 15 85 3 99 *Cofilin 2|*Chemotaxis|Phosphatidylinositol 3-Kinases|*Neutrophils|*Signal Transduction|protein kinase D|PRKCB protein, human|*Protein Kinase C beta|Cofilin 1|Actin|Phosphorylation|*Chemotaxis, Leukocyte|Cell Movement|Phosphoprotein Phosphatases|Actin Cytoskeleton|Microfilament Proteins|*Biochemical Phenomena 15 TBCK 25558065 Cell Rep 2015 10.1016/j.celrep.2014.12.015 96 0 11 56 *Whole Exome Sequencing|Genes, Recessive|Exome|Homozygote|Pedigree|Chromosome Mapping|Mutation|High-Throughput Nucleotide Sequencing|Sequence Analysis, DNA|Phenotype|Polymorphism, Single Nucleotide|Genetic Association Studies 16 TUT1 26243616 Plant Physiol. 2015 PMC4587440 10.1104/pp.15.00229 13 1 1 217 *Oryza|*Actins|*Receptors, Cyclic AMP|Plant Proteins|Gene Expression Regulation, Plant|Wiskott-Aldrich Syndrome Protein Family|Actin-Related Protein 2|Pollen Grains|Filaments, Actin|Cloning, Molecular|Edible Grain 15 ZBTB7C 26542693 Stroke 2015 PMC5704955 10.1161/STROKEAHA.115.010767 9 9 0 57 Animals|Mice|Humans|Brain Ischemia|Stroke|Quantitative Trait Loci|Genome-Wide Association Study|Genetic Predisposition to Disease|Chromosome Mapping|Polymorphism, Single Nucleotide|ANGPT1 protein, human|*Angiopoietin-1|Disease Models, Animal|ZBTB7C protein, human|Proteins 15 ZNF219 26222778 PLoS ONE 2015 PMC4519280 10.1371/journal.pone.0133901 3 3 2 67 *Colorectal Cancer|Gene Regulatory Networks|Gene Expression Profiling|*Regulatory Genes|Systems Biology|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Computational Biology|Transcription Factors|*Colonic Neoplasms|Microarray Analysis|Disease Progression 15 ADAP2 24854535 Biol. Chem. 2014 10.1515/hsz-2014-0107 3 3 1 62 Animals|Humans|*Neurodegenerative Diseases|*Neurons|ADP-Ribosylation Factor|GTPase-Activating Proteins|Adaptor Proteins, Signal Transducing|Kinesin|Axons|Actin|Protein Binding|Cytoskeleton|Signal Transduction Pathways|cnicin|*Sesquiterpenes|Cell Differentiation|ADAP2 protein, human|ADAP1 protein, human|Nerve Tissue Proteins 15 ADAP2 24711647 J. Med. 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Biol. 2014 PMC4333762 10.1007/978-1-4899-8032-8_7 16 12 4 68 lamina-associated polypeptide 2|*Membrane Proteins|Nuclear Envelope|Cell Nucleus|Endonucleases|*Thymopoietins|Lamins|Mitosis|Cytoplasm|Protein Domains|Retinoblastoma Protein|DNA 15 ARPP21 25351872 Mol Med Rep 2014 PMC4262513 10.3892/mmr.2014.2775 5 4 0 59 *Genes, Spliced|Quality of Life|*Gliomas|Glioblastoma|Brain Neoplasms|Gene Ontology|Gene Regulatory Networks|Bioinformatics|Protein Interaction Maps|Gene Expression Profiling|*Exon|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Downregulation|Transcriptome|MicroRNAs|Upregulation|Transcription Factors 15 CLUH 25349259 J. Cell Biol. 2014 PMC4210445 10.1083/jcb.201403129 25 7 2 105 *Organelle Biogenesis|Mitochondrial Proteins|Mitochondria|mRNA|RNA, Mitochondrial|Protein Biosynthesis|RNA|RNA-Binding Proteins|Cytosol|Binding Protein 15 CLUH 25192891 Mol. Biol. Rep. 2014 10.1007/s11033-014-3698-0 5 0 0 105 Mice|Animals|*Myotubes|*Receptors, Estrogen|Transcription Factors|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Muscle, Skeletal|Response Elements|Promoter Regions, Genetic|Signal Transduction|Upregulation|Gene Expression|Trans-Activators|Heat-Shock Proteins|Transcriptional Activation|Oxidation-Reduction 15 CLUH 25017872 BMC Genomics 2014 PMC4111849 10.1186/1471-2164-15-592 0 0 0 105 Mice|Animals|*Exons|Sequencing, RNA|High-Throughput Nucleotide Sequencing|Transcriptomes|Alternative Splicing|Gene Expression Profiling|Protein Isoforms|Base Sequence 15 CMTM1 25175386 Oncol. Rep. 2014 10.3892/or.2014.3429 2 2 0 8 Humans|Male|MARVEL Domain-Containing Proteins|Cellular Proliferation|Cell Line, Tumor|MCF-7 Cells|Tumor Necrosis Factor-alpha 15 DUSP11 24447265 Biochemistry 2014 PMC3985963 10.1021/bi401240x 9 10 1 83 Humans|*Phosphatase, Dual-Specificity|Active Site|Amino Acid Sequence|RNA triphosphatase|Acid Anhydride Hydrolases|Crystallography, X-Ray|Models, Molecular|RNA|Catalysis|Vaccinia virus 15 ERGIC2 24768165 Dev. Cell 2014 10.1016/j.devcel.2014.03.016 33 5 3 139 Humans|*Endoplasmic Reticulum|Golgi Apparatus|Protein Transport|Coat Protein Complex I|*Biological Transport|ADP-Ribosylation Factor 1|Integral Membrane Protein|Vesicular Transport Proteins|KDEL receptor|Receptors, Peptide|Intracellular Signaling Peptides and Proteins|HeLa Cells|Plasma Membrane 15 FGGY 24934327 Clin. Exp. Med. 2014 PMC4522272 10.1007/s10238-014-0298-1 10 1 0 8 Humans|*Colorectal Cancer|*Lymphatic Metastasis|Prognosis|Biomarkers, Tumor|Hydroxyprostaglandin Dehydrogenases|3-Hydroxysteroid Dehydrogenases|Lymph Nodes|*Colonic Neoplasms|Aldo-Keto Reductase Family 1 Member C3|AKR1C3 protein, human 15 FGGY 24906027 J. Anim. Breed. Genet. 2014 10.1111/jbg.12084 3 0 1 8 Male|Cattle|Animals|*Genome-Wide Association Study|Quantitative Trait Locus|Phenotype|Genotype|Single Nucleotide Polymorphisms|Breeding|Genetic Association Studies|Allele|Body Weight|Genomics 15 FGGY 24439956 Neurobiol. Aging 2014 10.1016/j.neurobiolaging.2013.12.018 2 0 0 8 Humans|*Single Nucleotide Polymorphism|Genome-Wide Association Study|Case-Control Studies|*Chinese|Amyotrophic lateral sclerosis 1|Amyotrophic Lateral Sclerosis|Genetic Predisposition to Disease|*Cohort Studies|Genotype|European Continental Ancestry Group|*Muscular Atrophy|Nucleotides 15 FIZ1 24956037 J. Proteome Res. 2014 10.1021/pr500392m 3 2 1 41 Humans|*Autocrine Communication|*Signal Transduction|Extracellular Signal-Regulated MAP Kinases|IGF1 protein, human|IGF-1|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|Keratinocytes|Protein-Serine-Threonine Kinases|ErbB Receptors|Cell Proliferation|Cells, Cultured|Protein Binding|Transcription Factors|Cell Differentiation 15 gal3st1 25277275 BMC Genet. 2014 PMC4189734 10.1186/s12863-014-0103-x 1 0 0 36 Swine|Animals|*Glycosphingolipids|*Fimbriae, Bacterial|Enterotoxigenic Escherichia coli|Fimbriae Proteins|Escherichia coli Infections|Escherichia coli Proteins|Bacterial Adhesion|Swine Diseases|Intestinal Mucosa|Antigens, Bacterial|Receptors, Cell Surface 15 gal3st1 25263565 Reprod. Domest. Anim. 2014 10.1111/rda.12423 8 0 1 36 Cattle|Male|Animals|Humans|*Genome-Wide Association Study|*Sperm Count|Genotype|Sperm Motility|Semen Analysis|Semen|SNPs|Spermatozoa|Genome|Genes, cdc|PRMT6 protein, human|Nuclear Proteins|Protein-Arginine N-Methyltransferases 15 GRID2IP 25248455 Gut 2014 10.1136/gutjnl-2014-307997 32 0 1 15 Humans|*Irritable Bowel Syndrome|*Genome-Wide Association Study|*Case-Control Studies|Genetic Predisposition|Genetic Association Studies|Polymorphism, Single Nucleotide|Constipation|Genotype 15 GRID2IP 27047918 Dermatopathology (Basel) 2014 PMC4772995 10.1159/000357402 0 1 0 15 Humans|*Vitiligo|*Leukocytes, Mononuclear|*Transcriptome Analysis|Melanocytes|*Sequencing, RNA|Transcriptome|*Hypopigmentation|*Transcriptome Sequencing, Whole|Skin|*Base Sequence|*Leukocytes|Cytokines|Oxidative Stress|Signal Transduction|*Mononuclear Phagocyte System 15 ILDR2 24790043 Yakugaku Zasshi 2014 10.1248/yakushi.14-00006-1 0 0 0 19 *Tight Junctions|Deafness, Autosomal Recessive|Hearing Loss, Sensorineural|Deafness, Autosomal Recessive 42|Deafness, Autosomal Recessive 49|Membrane Proteins|Tricellulin|Epithelial Cells|Mutations 15 MMP27 25091573 Tumour Biol. 2014 10.1007/s13277-014-2384-0 7 11 1 4 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Signal Transduction|FGFR2 protein, human|Fibroblast Growth Factor Receptor 2|Matrix Metalloproteinase 7|Phosphorylation|Cell Line, Tumor|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Extracellular Signal-Regulated MAP Kinases|Blotting, Western 15 MMP27 24810263 Mol. Hum. Reprod. 2014 10.1093/molehr/gau034 20 0 2 4 Female|Humans|*Endometriosis|Endometrium|*Endometrial Cycle|CD163 antigen|*Antigens, Differentiation, Myelomonocytic|Matrix Metalloproteinases|*Antigens, CD|*Receptors, Cell Surface|mRNA|*Macrophages 15 NAA25 25163837 J. Microbiol. 2014 10.1007/s12275-014-3694-z 1 0 1 77 *Saccharomyces cerevisiae|*Catalytic Domain|*Acetylesterase|Saccharomyces cerevisiae Proteins|N-Terminal Acetyltransferase B|Acetyltransferases|Acetylation|Protein Transport|Synthetic Genes|Gene Deletion|Cell Cycle|NatB protein, S cerevisiae 15 NDNF 24706764 J. Biol. Chem. 2014 PMC4022881 10.1074/jbc.M114.555789 13 2 0 53 Humans|Mice|Animals|*Endothelial Cell|enovin|*Nerve Growth Factors|NTF3 protein, human|Neovascularization, Physiologic|Ischemia|Nitric Oxide Synthase Type III|Signal Transduction|Proto-Oncogene Proteins c-akt|Hindlimb|Phosphorylation|*Neurons|*Transforming Growth Factor beta|Muscle, Skeletal 15 PPP1R14C 25058503 Neuroscience 2014 PMC4164601 10.1016/j.neuroscience.2014.07.020 8 8 2 90 Mice|Animals|*Quantitative Trait Loci|*Morphine|*DBA Mice|*Mice, Inbred C57BL|Chromosome Mapping|Alleles|Genetic Predisposition to Disease|Analgesics, Opioid|Species Specificity 15 RUSC2 25301550 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.09.122 0 10 1 57 Animals|Mitogen-Activated Protein Kinase 8|Mitogen-Activated Protein Kinase 10|Mitogen-Activated Protein Kinase 9|*MAP Kinase Signaling System|c-jun N-Terminal Kinase|Phosphorylation|Protein Binding|Signal Transduction|Neurons|microtubule-associated protein 1B|Microtubule-Associated Proteins|Adaptor Proteins, Signal Transducing 15 RUSC2 24664538 Genes Chromosomes Cancer 2014 10.1002/gcc.22168 6 0 1 57 Humans|*DNA Copy Number Variations|*Mutations|PAX5 Transcription Factor|Genes, p16|Acute Lymphoblastic Leukemia|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Base Sequence|In Situ Hybridization, Fluorescence|Sequencing, Next-Generation|MELK protein, human|Protein-Serine-Threonine Kinases|PDCD1LG2 protein, human|Programmed Cell Death 1 Ligand 2 Protein|PAX5 protein, human|RUSC2 protein, human|Carrier Proteins 15 SLC22A24 25164828 Arch. Toxicol. 2014 10.1007/s00204-014-1345-0 5 1 1 1 Male|Rats|Animals|*Cisplatin|*Rats, Wistar|Kidney|*Nephrosis|Creatinine|Dicarboxylic Acid Transporters|*Biomarkers|*Urinary Tract|*Early Diagnosis|*Renal Insufficiency|OAT5 protein, rat 15 SLC22A24 24800985 PLoS ONE 2014 PMC4011736 10.1371/journal.pone.0096057 11 0 1 1 Female|Humans|*Genome-Wide Association Study|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|*Heart Defects, Congenital|Case-Control Studies|Folic Acid|Mother|KCNJ4 protein, human|Potassium Channels, Inwardly Rectifying 15 SLC25A31 25031318 Reprod Sci 2014 PMC4287603 10.1177/1933719114542026 2 0 0 20 Male|Female|Mice|Animals|*Ovary|Meiosis|*Oogenesis|Spermatogenesis|Testis|Mitochondrial ADP, ATP Translocases|Adenine Nucleotide Translocator 2|Adenine Nucleotide Translocator 3|Spermatocytes|Adenosine Triphosphate|Mice, Knockout|Meiotic Prophase I|Amino Acid Sequence 15 SMR3B 25476335 Talanta 2014 10.1016/j.talanta.2014.09.026 2 0 0 14 Humans|*Proteases|Salivary Peptides|Histatins|*Endopeptidases|Saliva|Proteome|Spectrometry, Mass, Electrospray Ionization|Peptide Fragments|Chromatography, High Pressure Liquid|*Specimen Handling|Amino Acid Sequence 15 SMR3B 24908204 Ophthalmology 2014 10.1016/j.ophtha.2014.04.027 2 2 0 14 Humans|*Polymorphism, Single Nucleotide|*Graves Ophthalmopathy|Graves Disease|Chinese|Genetic Predisposition to Disease|Gene Frequency|Genotype|Alleles|CTLA-4 Antigen|Case-Control Studies|Taiwan|ABCF1 protein, human|ATP-Binding Cassette Transporters 15 SSH2 24497979 PLoS ONE 2014 PMC3907443 10.1371/journal.pone.0086790 24 10 6 99 Humans|Mice|Animals|STAT5B protein, human|STAT5A protein, human|*STAT5 Transcription Factor|*T Cells|*Tumor Suppressor Proteins|Gene Expression Regulation|DNA-Binding Proteins|Trans-Activators|Base Sequence|Genes, Regulator|Cell Proliferation|Amino Acid Sequence|DOCK8 protein, human|Guanine Nucleotide Exchange Factors|Dock8 protein, mouse 15 TCFL5 24814791 Appl. Environ. Microbiol. 2014 PMC4136110 10.1128/AEM.00761-14 9 0 1 661 Humans|*Bifidobacterium bifidum|*Peptidoglycan|*Histidine|*Cysteine|Bifidobacterium|amidase|*Amidohydrolases|Probiotic|*Cysteine Proteases|Intestines|*Cell Differentiation|Bacterial Proteins|Cell Wall|Cells, Cultured|Dendritic Cells 15 TUT1 25142229 Tumour Biol. 2014 10.1007/s13277-014-2395-x 4 3 0 217 *RNA, Micro|*Lipogenesis|*Osteosarcoma|Bone Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|Downregulation|Cell Movement|Genes, Tumor Suppressor|3' Untranslated Regions|Cell Line, Tumor|RNA, Small Interfering|Upregulation|Binding Sites|*Nucleotidyltransferases 15 ZNF219 25376664 Acta Odontol. Scand. 2014 10.3109/00016357.2014.956143 3 0 0 67 Humans|Osteogenesis|*Transcriptome|*Dental Sac|*Stem Cells|Cell Differentiation|Core Binding Factor Alpha 1 Subunit|Sp7 Transcription Factor|Transcription Factors|Homeodomain Proteins|Cells, Cultured|Dexamethasone|Bone Regeneration|Alkaline Phosphatase 15 ADAP2 23285209 PLoS ONE 2013 PMC3527619 10.1371/journal.pone.0052867 6 17 0 62 Humans|*Tubulin|HeLa Cells|*Microtubules|Microtubule-Associated Proteins|Nocodazole|Acetylation|Cytoplasm|Protein Processing, Post-Translational|cnicin|*Sesquiterpenes|Transfections|Polymerization 15 AKIRIN1 23516508 PLoS ONE 2013 PMC3596298 10.1371/journal.pone.0058554 17 38 3 132 Mice|Animals|MSTN protein, human|*Myostatin|*Glucocorticoids|Satellite Cells, Skeletal Muscle|Myogenin|Cell Differentiation|Muscle Atrophy|Muscle Fibers, Skeletal|Cell Proliferation|Upregulation|Regeneration|Muscle, Skeletal|Signal Transduction|Cells, Cultured|Akirin1 protein, mouse|Nuclear Proteins 15 ANKLE1 23717510 PLoS ONE 2013 PMC3661550 10.1371/journal.pone.0063925 33 9 4 68 Humans|Male|Genome-Wide Association Study|Linkage Disequilibrium|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Allele|Genetic Predisposition to Disease|Transcription Factors|Enhancer Elements, Genetic|Chromatin|Gene Frequency|*Risk|Gene Expression Regulation, Neoplastic|Response Element|Prostatic Neoplasms 15 ARPP21 24127197 Am. J. Med. Genet. A 2013 10.1002/ajmg.a.36257 4 0 1 59 Child|Humans|*Intellectual Disability|*DNA Copy Number Variations|Chromosome Deletion|Comparative Genomic Hybridization|Abnormalities, Multiple|Facies|*Syndromes|Phenotype|*Chromosome Structures|CLASP2 protein, human|Microtubule-Associated Proteins 15 ARPP21 23593441 PLoS ONE 2013 PMC3620385 10.1371/journal.pone.0061231 9 11 4 59 Humans|*Periodontal Ligament|*Dentition, Permanent|Tooth, Deciduous|*Ligament|Gene Expression|Cells, Cultured|Gene Expression Profiling|Periodontium|Up-Regulation|DOCK3 protein, human|Nerve Tissue Proteins|Guanine Nucleotide Exchange Factors 15 C2CD4A 23522043 Neuron 2013 10.1016/j.neuron.2013.01.018 27 5 3 19 Animals|Mice|*Sodium|Caenorhabditis elegans|Caenorhabditis elegans Proteins|*Locomotion|Neurons|Interneurons|Sodium Channel|Synaptic Transmission|Axons|Nerve Tissue Proteins|*Nervous System Physiological Phenomena|Endoplasmic Reticulum 15 DUSP11 24274083 ACS Chem. Biol. 2013 PMC3934374 10.1021/cb400421a 2 7 0 83 *Kinase|Salmonella Infections|Salmonella typhimurium|*Bacterial Infection|*Enzyme Inhibitors|*Protein Kinase Inhibitors|Proto-Oncogene Proteins c-akt|Mycobacterium tuberculosis|*Gene Silencing|Phosphorylation|Signal Transduction|Antibiotics|Host-Pathogen Interactions|Dual-Specificity Phosphatases|RNA, Small Interfering|*Biochemical Phenomena 15 ERGIC2 24303950 DNA Cell Biol. 2013 10.1089/dna.2013.2225 1 0 0 139 Humans|Male|Golgi Apparatus|Endoplasmic Reticulum|Protein Transport|Vesicular Transport Proteins|Membrane Proteins|Carrier Proteins|Protein Binding|HeLa Cells|Upregulation 15 FGGY 24348429 Front Psychiatry 2013 PMC3842585 10.3389/fpsyt.2013.00154 14 6 1 8 Male|Female|Humans|*Bipolar Disorder|*Anxiety Disorders|*Genomics|Comorbidity|Suicide, Attempted|Genetic Predisposition to Disease|Siblings|Family Members|Mood|*Signal Transduction|VRK2 protein, human|Protein-Serine-Threonine Kinases 15 ILDR2 24212375 Cell Struct. Funct. 2013 10.1247/csf.13015 16 0 1 19 Animals|Mice|*MARVEL Domain Containing 2 Protein|*Endothelial Cells|Tight Junctions|Cells, Epithelial|*Retina|*Brain|Ildr1 protein, mouse|Receptors, Cell Surface 15 ILDR2 23826244 PLoS ONE 2013 PMC3691114 10.1371/journal.pone.0067234 0 12 1 19 Mice|Animals|*DBA Mice|*Liver|*Endoplasmic Reticulum|Fatty Liver|Lipogenesis|Triglycerides|Lipid Metabolism|Mice, Obese|Hepatocytes|Endoplasmic Reticulum Stress|Cholesterol|Obesity|Insulin|*Homeostasis|ILDR2 protein, mouse|Membrane Proteins 15 MMP27 24137342 Oncol Lett 2013 PMC3789032 10.3892/ol.2013.1391 4 6 0 4 *DNA Mutational Analysis|Thyroid Neoplasms|Proto-Oncogene Proteins B-raf|Mutation|Cell Line, Tumor 15 NAA25 23460240 Arthritis Rheum. 2013 10.1002/art.37923 14 1 3 77 Humans|*Rheumatoid Arthritis|HLA-DRB1 Chains|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Chromosome 1|Linkage Disequilibrium|Genotype|Alleles|Case-Control Studies 15 PFN3 24052059 Int. J. Legal Med. 2013 10.1007/s00414-013-0918-4 5 0 1 11 Female|*DNA Methylation|Veillonella atypica|Forensic Genetics|Semen|Saliva|Body Fluids|*DNA|DNA Fingerprinting|Multiplex Polymerase Chain Reaction|Vagina|16S Ribosomal RNA 15 PFN3 23719187 J. Hum. Genet. 2013 10.1038/jhg.2013.59 8 0 1 11 Humans|Genome-Wide Association Study|Japan|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|Case-Control Studies|Asian Continental Ancestry Group|Alleles|*Kidney Calculi|Genotype|Odds Ratio|*Epidemiologic Research Design|Risk Factors 15 RSRC1 24214394 Genome Res. 2013 PMC3912420 10.1101/gr.156224.113 9 0 0 134 *Nasopharyngeal Carcinoma|In Situ Hybridization, Fluorescence|Neoplasm Recurrence, Local|Transcription Factors|DNA-Binding Proteins|Nuclear Proteins|Gene Fusions|Carcinoma, Mucoepidermoid|Oncogene Proteins, Fusion|Nasopharyngeal Neoplasms 15 RSRC1 23563607 Nat. Genet. 2013 PMC3973018 10.1038/ng.2606 226 4 24 134 Humans|*Anthropometry|Body Mass Index|Waist to Hip Ratio|Genome-Wide Association Study|*Phenotype|Obesity|Body Weight|Genetic Predisposition to Disease|Quantitative Trait Loci|Polymorphism, Single Nucleotide|European Continental Ancestry Group|HS6ST3 protein, human|Sulfotransferases 15 SLC22A24 24199190 Biomed Res Int 2013 PMC3807842 10.1155/2013/283429 1 5 0 1 Male|Rats|Animals|*Rats, Wistar|*Kidney|Dicarboxylic Acid Transporters|Organic Anion Transporters, Sodium-Dependent|*Vascular Calcification|Creatinine|Western Blotting|Symporters|Biomarkers|OAT5 protein, rat 15 SLC22A24 23649842 Arch. Toxicol. 2013 10.1007/s00204-013-1062-0 5 1 0 1 Male|Rats|Animals|*Cisplatin|*Rats, Wistar|*Kidney|*Nephrosis|Dicarboxylic Acid Transporters|*Biomarkers|Acute Kidney Injury|Creatinine|Kidney Tubules|Western Blotting|Blood Urea Nitrogen|OAT5 protein, rat 15 SLC25A31 24056384 J. Mol. Graph. Model. 2013 PMC3821932 10.1016/j.jmgm.2013.08.016 3 1 1 20 Humans|Male|Mice|Animals|*Molecular Docking Simulation|Mitochondrial ADP, ATP Translocases|Spermatogenesis|Amino Acid Sequence|Mammals|Mitochondria 15 SLC25A31 23506884 Mol. Aspects Med. 2013 10.1016/j.mam.2012.05.006 29 1 1 20 Humans|*ADP,ATP Carrier|*Mitochondria|Adenine Nucleotide Translocator 3|Adenine Nucleotide Translocator 1|Saccharomyces cerevisiae Proteins|Adenine Nucleotide Translocator 2|Saccharomyces cerevisiae|Amino Acid Sequence|Oxidative Phosphorylation|Protein Conformation|Programmed Cell Death|Adenosine Triphosphate|Adenosine Diphosphate 15 SSH2 23416984 Oncogene 2013 10.1038/onc.2013.27 4 7 0 99 Humans|*Folliculin|*Serine|Renal Cell Carcinoma|FLCN protein, human|*Tumor Suppressor Proteins|*Genes, Tumor Suppressor|*Proto-Oncogene Proteins|Birt-Hogg-Dube Syndrome|Kidney Neoplasms|*Carcinoma|*Phosphoric Monoester Hydrolases|Cell Line, Tumor|Mutations|Apoptosis 15 TBCK 23977024 PLoS ONE 2013 PMC3747267 10.1371/journal.pone.0071349 12 24 2 56 Humans|MTOR protein, human|Mammalian Target of Rapamycin|*Signal Transduction|*Cell Proliferation|Proto-Oncogene Proteins c-akt|TBCK protein, human|Ribosomal Protein S6 Kinases, 70-kDa|Phosphatidylinositol 3-Kinases|Phosphorylation|Cell Cycle|*Cell Size|Cell Line, Tumor 16 TCFL5 23444080 Andrology 2013 10.1111/j.2047-2927.2013.00069.x 0 1 0 661 Male|Mice|Rabbits|Animals|*Spermatids|*Centrioles|*Transcription Factor|Spermatogenesis|Testis|Spermatozoa|Nuclear Proteins|Cell Cycle Proteins|Sperm Flagellum|Phosphoproteins|Spermatozoa Maturation|Amino Acid Sequence|Meig1 protein, mouse 15 TP53I11 23684732 Biochim. Biophys. Acta 2013 10.1016/j.bbapap.2013.05.006 3 0 1 22 Humans|*Proteolysis|*Tumor Microenvironment|Tandem Mass Spectrometry|Reproducibility of Results|*Colonic Neoplasms|*Colon|lantibiotic Pep5|Peptides|Proteomics|Proteome|colon-specific antigen|Antigens, Neoplasm|Cell Line, Tumor|MACC1 protein, human|Transcription Factors|Protein Processing, Post-Translational|Software|Proteases 15 TUT1 23874977 PLoS ONE 2013 PMC3715485 10.1371/journal.pone.0069630 16 1 2 217 Humans|*RNA, Micro|*Nucleotidyltransferases|RNA Nucleotidyltransferases|Arabidopsis Proteins|Arabidopsis|Uridine|Nucleotides|TUT1 protein, human 15 ZNF219 24269816 Biochem. Biophys. Res. Commun. 2013 10.1016/j.bbrc.2013.11.042 0 0 0 67 Animals|*Zebrafish|*Synuclein|*Notochord|Zebrafish Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|SOX9 Transcription Factor|Amino Acid Sequence|Gene Expression|Cloning, Molecular|Zinc Fingers 15 ZNF219 24155663 Int. J. Biol. Sci. 2013 PMC3805895 10.7150/ijbs.7126 0 14 0 67 Animals|*Zebrafish|*Notochord|Zebrafish Proteins|Embryo, Nonmammalian|Body Patterning|Gene Expression Regulation, Developmental|*Gene Expression|Embryogenesis|PHF20 protein, human|*Biomarkers, Tumor|Hindbrain|In Situ Hybridization|Morpholinos|*Collagen|Amino Acid Sequence|Cloning, Molecular|Collagen Type II|mRNA 15 ZNF81 23871722 Am. J. Hum. Genet. 2013 PMC3738825 10.1016/j.ajhg.2013.06.013 83 0 8 22 Humans|*Exome|Genes, X-Linked|*Mutations|Intellectual Disability|Whole Exome Sequencing|High-Throughput Nucleotide Sequencing|Pedigree|Genes, Regulator|IGBP1 protein, human|Intracellular Signaling Peptides and Proteins|Cohort Studies|CLIC2 protein, human|Chloride Channels|CNKSR2 protein, human|Adaptor Proteins, Signal Transducing|NAA10 protein, human|N-Terminal Acetyltransferase A|N-Terminal Acetyltransferase E 15 ANKLE1 22399800 J. Cell. Sci. 2012 PMC4335191 10.1242/jcs.098392 22 4 2 68 Animals|*DNA Cleavage|*Endonucleases|emerin|Nuclear Proteins|Membrane Proteins|Nuclear Envelope|Cell Nucleus|DNA Damage|Chromatin|Amino Acid Sequence 15 ARPP21 23019226 Cancer Res. 2012 10.1158/0008-5472.CAN-12-1507 35 2 5 59 Humans|*Stem Cell Factor|Phosphatidylinositol 3-Kinases|miRNAs|Epithelial-Mesenchymal Transition|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Snail Family Transcription Factors|Downregulation|Cell Line, Tumor|*Cells, Epithelial|*Chromosome 3|Transcription Factors|Signal Transduction|*Chromosome Structures|Stem Cell|MIRN128 microRNA, human 15 C2CD4A 23185617 PLoS ONE 2012 PMC3503928 10.1371/journal.pone.0050418 8 3 2 19 *Diabetes Mellitus, Type 2|*Cardiovascular Diseases|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Gene Frequency|Genotype|Risk Factors 15 C2CD4A 22688542 Diabetes Care 2012 PMC3402252 10.2337/dc11-2006 0 5 9 19 Humans|*Diabetes Mellitus, Type 2|*Alleles|*Insulin|Japan|Transcription Factor 7-Like 2 Protein|Zinc Transporter 8|Homeodomain Proteins|Cyclin-Dependent Kinase Inhibitor p15|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Transcription Factors|Genome-Wide Association Study|tRNA Methyltransferases|*Risk Factors|Asian Continental Ancestry Group|Cyclin-Dependent Kinase 5|Potassium Channels, Inwardly Rectifying 15 ERGIC2 22613993 Cell. Physiol. Biochem. 2012 10.1159/000188338 3 6 0 139 OTOF protein, human|*Membrane Proteins|Protein Transport|Hair Cells, Auditory, Inner|Golgi Apparatus|Cochlea|Synapses|Plasma Membrane|*Brain|Protein Binding 15 FGGY 22885293 J. Bacteriol. 2012 PMC3458674 10.1128/JB.01136-12 8 0 0 8 *Thermotoga maritima|*Sugar|Regulon|Carbohydrate Metabolism|*Carbohydrates|Genome, Bacterial|Genomics|Bioinformatics|Substrate Specificities|Bacterial Proteins|Kinases|Phosphorylation|Bacteria|Carbon 15 FGGY 22215998 PLoS Comput. Biol. 2012 PMC3245297 10.1371/journal.pcbi.1002318 23 3 2 8 Phylogeny|ribulokinase|Phosphotransferases (Alcohol Group Acceptor)|Amino Acid Sequence|Evolution, Molecular|ribulose|Pentoses|Proteins|Multigene Family|Genomics|Substrate Specificities|Genome 15 FUBP3 23121659 J. Neurochem. 2012 10.1111/jnc.12079 2 2 0 105 Humans|Animals|Rats|*mRNA|MAP2 protein, human|*Microtubule-Associated Protein 2|*Neurons|*RNA Binding Protein|Dendrites|RNA|Hippocampus|Microtubule|Trans-Acting Factor|Cells, Cultured 15 gal3st1 22709888 Epigenetics Chromatin 2012 PMC3418201 10.1186/1756-8935-5-8 34 19 5 36 Male|*Nucleosomes|*Consensus|Chromatin|CCCTC-Binding Factor|DNA-Binding Proteins|*Regulator Gene|DNA Methylation|cohesins|Chromosomal Proteins, Non-Histone|Repressor Proteins|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Zinc Finger|*Germ Cell|Cell Line, Tumor|Protein Binding|Cell Cycle Proteins 15 ILDR2 23239027 J. Cell. Sci. 2012 10.1242/jcs.116442 61 0 4 19 Humans|Animals|Mice|*MARVEL Domain Containing 2 Protein|Tight Junctions|Deafness, Autosomal Recessive 42|Hearing Loss, Sensorineural|Deafness, Autosomal Recessive 49|Epithelium|Cells, Epithelial|Membrane Proteins|Hearing|Mutations|Extracellular Space|Cell Line|ILDR1 protein, human|Receptors, Cell Surface|Ildr1 protein, mouse|ILDR2 protein, mouse 15 MMP27 22822400 Front Pharmacol 2012 PMC3398411 10.3389/fphar.2012.00140 40 9 2 4 Animals|*Tumor Microenvironment|Tumors|Neoplastic Processes|Neovascularization, Pathologic|Extracellular Matrix|MMP11 protein, human|Matrix Metalloproteinase 11|Metalloendopeptidases|MMP8 protein, human|Matrix Metalloproteinase 8|Cell Proliferation|Apoptosis 15 NAA25 22326526 Gene 2012 10.1016/j.gene.2012.01.089 5 1 1 77 *Diabetes Mellitus, Type 1|Estonia|Protein Tyrosine Phosphatase, Non-Receptor Type 22|Genetic Predisposition|HLA-DQ beta-Chains|HLA-DQ Antigens|Alleles|Insulin|Polymorphism, Single Nucleotide|Genotype|CTLA-4 Antigen|*Profiles, Genetic|Autoantibodies 15 NDNF 22810813 Diabetologia 2012 10.1007/s00125-012-2643-9 8 6 3 53 *Insulin-Secreting Cells|*Palmitates|Forkhead Box Protein O1|Apoptosis|*Cell Death|Forkhead Transcription Factors|*Cells, Cultured|*Chromatin Immunoprecipitation|Gene Expression Regulation|Phosphorylation|Fatty Acids|*DNA 15 PFN3 22653424 Int. 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Legal Med. 2012 10.1007/s00414-012-0719-1 6 0 2 11 Humans|Male|Female|Aged|*DNA Methylation|*B-DNA|CpG Islands|Forensic Genetics|Cervix Mucus|DNA Fingerprinting|Saliva|Semen|PCR, Multiplex|Body Fluids|Genetic Markers|DNA|DNA Restriction Enzymes|DACT1 protein, human|Nuclear Proteins|Adaptor Proteins, Signal Transducing 15 PFN3 22396660 PLoS Genet. 2012 PMC3291538 10.1371/journal.pgen.1002541 19 0 2 11 Humans|*Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|Genetic Loci|Polymorphism, Single Nucleotide|*Kidney Calculi|Asian Continental Ancestry Group|Case-Control Studies|Genotype|Odds Ratio|Glomerular Filtration Rate 15 SLC25A31 22978616 BMC Genomics 2012 PMC3477019 10.1186/1471-2164-13-482 2 2 1 20 Humans|Mitochondrial ADP, ATP Translocases|Adenine Nucleotide Translocator 3|Adenine Nucleotide Translocator 1|Adenine Nucleotide Translocator 2|Sequences, Nucleotide|Gene Expression Regulation|Mitochondria|*Isoforms|Promoter Regions, Genetic|Phylogeny|Bioenergetics 15 SMR3B 23194029 Mol Oral Microbiol 2012 10.1111/omi.12011 10 0 2 14 Humans|lipopolysaccharide B|*Lipopolysaccharides|*Aggregatibacter actinomycetemcomitans|*alpha-Amylase|PIP protein, human|Carrier Proteins|Salivary Proteins|lipopolysaccharide-binding protein|Acute-Phase Proteins|Membrane Glycoproteins|Glycoproteins|Saliva|TLR4 protein, human|Toll-Like Receptor 4|Aggressive Periodontitis|Cystatins|*Amylase|CXCL10 protein, human 15 SMR3B 23053383 Eur Arch Otorhinolaryngol 2012 10.1007/s00405-012-2201-6 2 0 0 14 Humans|Animals|Mice|*Risk Factors|*Submandibular Gland|Neoplasm Recurrence, Local|*Oropharyngeal Neoplasms|*Mouth Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Carcinoma, Squamous Cell|Prognosis|Kaplan-Meier Analysis|Neoplasm Staging|Disease-Free Survival|TYRP1 protein, human|*Membrane Glycoproteins|Immunohistochemistry|Biomarkers, Tumor|Head and Neck Neoplasms 15 TCFL5 22897724 Leuk. Lymphoma 2012 10.3109/10428194.2012.710330 12 0 1 661 Child|Humans|*Prognosis|*Acute Lymphoblastic Leukemia|Asparaginase|Vincristine|Daunorubicin|Disease-Free Survival|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Treatment Outcome|Prednisolone|Prednisone|Antineoplastic Combined Chemotherapy Protocols|Brazil|SHOC2 protein, human|Intracellular Signaling Peptides and Proteins|KCNN4 protein, human|Intermediate-Conductance Calcium-Activated Potassium Channels|TRIM24 protein, human 15 TP53I11 22962263 Cancer Res. 2012 10.1158/0008-5472.CAN-12-1383 64 0 0 22 Humans|*T-Lymphocytes, Cytotoxic|Cytotoxicity, Immunologic|*Hypoxia|miRNA|Cell Line, Tumor|Tumor Microenvironment|Melanoma|Cancer Stem Cells|Genes, Homeobox|Flow Cytometry|*Cell Count|*Cell Death|MIRN210 microRNA, human 15 TP53I11 22547548 Infect. Immun. 2012 PMC3416477 10.1128/IAI.00154-12 24 0 3 22 Humans|*Ehrlichia chaffeensis|Type 1 Secretion System|Host-Pathogen Interactions|*Cytoplasm|Ehrlichiosis|Bacterial Proteins|Microbial Viability|Cell Signaling|Protein Binding|Co-Immunoprecipitation|RNA Interference|Monocytes|THP-1 Cells|DAZAP2 protein, human|RNA-Binding Proteins|PSMB1 protein, human|Proteasome Endopeptidase Complex 15 TP53I11 22528125 Immunol. Res. 2012 10.1007/s12026-012-8337-z 10 5 1 22 Humans|*Hepatitis B virus|*Hepatitis C|Hepatocellular Carcinoma|*Hepatitis A|Hepatitis B|Liver Neoplasms|Regulatory Network, Gene|Liver Cirrhosis|Hepacivirus|Signal Transduction|*B-Lymphocytes|Genes, cdc|Cell Proliferation|Phosphorylation|Apoptosis|Cell Cycle|REG1A protein, human|Lithostathine 15 ZBTB7C 22331133 J. Lipid Res. 2012 PMC3307652 10.1194/jlr.M022178 6 4 0 57 Mice|Animals|SREBF1 protein, human|*Sterol Regulatory Element Binding Protein 1|*Promoter Regions, Genetic|Fatty Acid Synthase, Type I|Protein Binding|Fatty Acid Synthases|Cell Proliferation|Proteins|Lipogenesis|Zinc Fingers|Electrophoretic Mobility Shift Assay|DNA 15 ZBTB7C 22253232 Cancer Res. 2012 10.1158/0008-5472.CAN-11-2433 13 7 1 57 Humans|Mice|Animals|*Tumor Suppressor Protein p53|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|Histone H3|Activation, Transcriptional|Transcription, Genetic|*Genes, cdc|Sp1 Transcription Factor|Promoter Regions, Genetic|Kruppel-Like Transcription Factors|Repressor Proteins|Zinc Finger|Cell Proliferation|Gene Expression Regulation|Binding, Competitive|ZBTB7C protein, human|Proteins|Bcor protein, mouse 15 ZNF81 22634100 Gene 2012 10.1016/j.gene.2012.05.031 5 0 0 22 Humans|Male|Child, Preschool|*Autistic Disorder|Genome-Wide Association Study|*Chromosome Banding|Mental Retardation, X-Linked|Chromosomes, Human, X|*Chromosome Structures|Mental Retardation|Zinc Finger|Chromosome Mapping|Mutations|Pedigree|Growth Disorders 15 AKIRIN1 21300161 Fish Shellfish Immunol. 2011 10.1016/j.fsi.2011.01.028 4 0 1 132 Animals|*Scophthalmus maximus|*Cloning, Molecular|Sequence Alignments|Amino Acid Sequence|Fish Proteins|cDNA|Fish Diseases|Base Sequence|Gene Expression Profiling|Cell Line|Phylogeny|Spleen 15 ARPP21 22193543 Cell Death Differ. 2011 PMC3354056 10.1038/cdd.2011.190 59 6 5 59 Carcinoma, Non-Small-Cell Lung|*Tumor Suppressor Protein p53|Lung Cancer|*Gain of Function Mutation|Cisplatin|Apoptosis|Cyclin-Dependent Kinase Inhibitor p21|Antineoplastic Agents|Drug Resistance, Neoplasm|Cell Line, Tumor|Doxorubicin|Up-Regulation|Cell Death|mRNA|MicroRNAs 15 C2CD4A 21909839 Diabetologia 2011 10.1007/s00125-011-2293-3 14 0 2 19 Humans|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|Japan|Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|SPRY2 protein, human|Membrane Proteins|Intracellular Signaling Peptides and Proteins|CDC123 protein, human|Cell Cycle Proteins|CAMK1D protein, human|Calcium-Calmodulin-Dependent Protein Kinase Type 1 15 C2CD4A 21873549 Diabetes 2011 PMC3178302 10.2337/db11-0415 136 2 9 19 *Proinsulin|*Diabetes Mellitus, Type 2|*Fasting|*Genome-Wide Association Study|Insulin|Transcription Factor 7-Like 2 Protein|Insulin Resistance|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Genetic Variation 15 C2CD4A 21799836 PLoS ONE 2011 PMC3142153 10.1371/journal.pone.0022353 26 0 6 19 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Asians|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genetic Loci|Case-Control Studies|Genotype 15 C2CD4A 21249489 Diabetologia 2011 10.1007/s00125-010-2031-2 13 2 2 19 Humans|Genome-Wide Association Study|Diabetes Mellitus, Type 2|Denmark|Insulin Secretion|Insulin-Secreting Cells|Glucose Tolerance Test|Insulin|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Glucose|Alleles|Genotype|Case-Control Studies|VPS13C protein, human|Proteins 15 DUSP11 21324547 Eur. 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Cell Biol. 2011 10.1016/j.ejcb.2010.11.010 13 0 1 83 Animals|Humans|*RNA Precursors|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn's Disease|Colon|*RNA Splicing|IER3 protein, human|Membrane Proteins|Apoptosis Regulatory Proteins|DUSP11 protein, human|Dual-Specificity Phosphatases 15 FIZ1 21602290 Plant Cell 2011 PMC3123953 10.1105/tpc.110.079442 18 0 4 41 *Arabidopsis|*Gravity Sensing|*Actins|*E3 Ligase|Gravitropism|Amyloplasts|Arabidopsis Proteins|*Filaments, Actin|Plant Shoots|Plant Roots|Inflorescence|latrunculin B|Thiazolidines|Gravity|Bridged Bicyclo Compounds, Heterocyclic 15 FIZ1 21539722 Stem Cell Res Ther 2011 PMC3226292 10.1186/scrt62 1 0 0 41 Humans|*Prognosis|*Leukemia, Myeloid, Acute|Neoplastic Stem Cells|Nuclear Proteins|Mutation|Karyotyping|Acute Disease|Signature, Gene Expression 15 FUBP3 25212137 Food Chem 2011 10.1016/j.foodchem.2011.03.022 17 1 1 105 *Internal Ribosome Entry Sites|*Enterovirus A, Human|*Enterovirus|kaempferol|*Kaempferols|Chromatography, Liquid|Tandem Mass Spectrometry|Enterovirus Infections|Virus Replication|Gene Expression Regulation, Viral|5' Untranslated Regions|Viral Proteins|Protein Biosynthesis|Trans-Acting Factors|Cell Line, Tumor 15 FUBP3 21356256 J. Hepatol. 2011 10.1016/j.jhep.2011.02.019 12 3 5 105 Humans|Carcinoma, Hepatocellular|Liver Neoplasms|*Ubiquitin|E3 Ubiquitin Ligase|*Cell Nucleus|Nuclear Proteins|Cell Proliferation|Cell Line, Tumor|Cell Movement|Gene Expression Regulation, Neoplastic|RNA Interference|RNA, Small Interfering|Apoptosis 15 FUBP3 21252297 Nucleic Acids Res. 2011 PMC3089454 10.1093/nar/gkq1295 10 13 2 105 Humans|HEK293 Cells|3' Untranslated Region|*Microsatellite|mRNA|RNA-Binding Proteins|Protein Biosynthesis|Transfection|FGF9 protein, human|Fibroblast Growth Factor 9 15 PFN3 21626087 Int. J. Legal Med. 2011 10.1007/s00414-011-0569-2 6 0 2 11 Humans|Male|Female|*DNA Methylation|Forensic Genetics|CpG Islands|Semen|DNA Fingerprinting|Saliva|Spermatozoa|Body Fluids|Sequence Analysis, DNA|Bodily Secretions|PCR|DNA|Genes, Homeobox|DACT1 protein, human|Nuclear Proteins|Adaptor Proteins, Signal Transducing|HOXA4 protein, human|Homeodomain Proteins 15 RUSC2 21737958 Cell Struct. Funct. 2011 10.1247/csf.11001 32 3 2 57 Rats|Animals|rab GTPases|ADP-Ribosylation Factors|GTPase-Activating Proteins|PC12 Cells|Protein Transport|Neurite Outgrowth|Neurites|Mutagenesis, Site-Directed|Protein Domain|NGF protein, human|Nerve Growth Factor|Guanosine Triphosphate 15 SLC25A31 21858006 PLoS ONE 2011 PMC3155547 10.1371/journal.pone.0023122 8 8 0 20 Male|Female|Mice|Animals|*Lizard|Phylogeny|*Mammals|Mitochondrial ADP, ATP Translocases|Adenine Nucleotide Translocator 3|*Genomics|Adenine Nucleotide Translocator 2|*Germ Cells|*Biological Evolution|Spermatogenesis|Genomes|Synteny|Gene Expression|Birds|Testis|Adenosine Triphosphate 15 SLC25A31 21827840 Gene 2011 10.1016/j.gene.2011.07.024 4 0 0 20 Humans|Male|Animals|Phylogeny|*Gene Expression Regulation|Mitochondrial ADP, ATP Translocases|Promoter Regions, Genetic|*Glycolysis|*Protein Isoforms|Spermatogenesis|Computational Biology|Introns|Mammals|Adenine Nucleotides 15 SLC25A31 21532989 PLoS ONE 2011 PMC3080916 10.1371/journal.pone.0019250 6 7 0 20 Male|Humans|Mice|Animals|*Saccharomyces cerevisiae|SLC25A31 protein, human|*Mitochondrial ADP, ATP Translocases|Adenosine Diphosphate|Adenosine Triphosphate|Mitochondria|Amino Acid Sequence|Sequence Homology, Amino Acid|Phylogeny 15 SSH2 21868701 Arterioscler. 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Biol. 2011 PMC3204790 10.1161/ATVBAHA.111.232769 15 25 0 99 *Neointima|*Muscle, Smooth, Vascular|*Cell Movement|*Microfilament Proteins|Myocytes, Smooth Muscle|Platelet-Derived Growth Factor|Actins|Cells, Cultured|Phosphorylation|*Protein Isoforms|Actin Depolymerizing Factors 15 TCFL5 22207630 Gut 2011 10.1136/gutjnl-2011-301153 54 2 5 661 *Aurora Kinase A|*Adenomas|*Colorectal Cancer|Carcinoma|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Disease Progression|Cell Transformation, Neoplastic|Gene Dosage|Gene Expression Profiling 15 TP53I11 21755009 PLoS ONE 2011 PMC3130766 10.1371/journal.pone.0021920 14 2 0 22 Humans|*African Americans|Genome-Wide Association Study|Nigeria|Carboplatin|Cisplatin|SNPs|Antineoplastic Agents|European Continental Ancestry Group|Phenotypes|African Continental Ancestry Group|Pharmacogenetics|doxifluridine|Floxuridine|Genetic Variation|Cytarabine 15 TUT1 21813625 Genome Res. 2011 PMC3166830 10.1101/gr.118059.110 137 0 19 217 Humans|Animals|*RNA, Micro|*Transcriptome|*Transferases|Caenorhabditis elegans|Gene Expression Profiling|Sequencing, Next-Generation|Nucleotides|PAPD4 protein, human|MTPAP protein, human|DNA-Directed RNA Polymerases|Mitochondrial Proteins 15 ZBTB7C 21804610 Oncogene 2011 10.1038/onc.2011.331 4 10 0 57 Mice|Animals|*Transcriptional Activation|*Binding, Competitive|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|*Transcription Factor|ZBTB17 protein, human|Kruppel-Like Transcription Factors|*Proto-Oncogene Proteins|Promoter Regions, Genetic|Cell Proliferation|*Genes, cdc|Zinc Fingers|Tumor Suppressor Protein p53|Protein Binding|Gene Expression Regulation|Acetylation|Cell Line, Tumor|Histone H3 15 ZBTB7C 21426945 Eur J Med Genet 2011 10.1016/j.ejmg.2011.03.008 4 0 0 57 Male|*Intellectual Disability|Chromosome Deletion|Karyotyping|Translocation, Genetic|In Situ Hybridization, Fluorescence|Abnormalities, Multiple|Chromosome Inversion|Phenotype|Base Sequence 15 ADAP2 20844836 Mol. Med. 2010 PMC3022985 10.2119/molmed.2010.00079 13 0 1 62 Humans|Nerve Sheath Neoplasms|Plexiform Neurofibromas|Neurofibromas|Neurofibromatosis 1|Neurofibromin 1|Gene Expression Regulation, Neoplastic|Downregulation|Upregulation|Gene Expression Profiling|MicroRNAs|Schwann Cells|Signal Transduction|RNF135 protein, human|Ubiquitin-Protein Ligases|ATAD5 protein, human|ATPases Associated with Diverse Cellular Activities|DNA-Binding Proteins 15 AKIRIN1 20804733 Biochem. Biophys. Res. Commun. 2010 10.1016/j.bbrc.2010.08.110 6 0 0 132 Animals|*Muscle Development|*Atlantic Salmon|*Gene Regulatory Networks|Myoblasts|Myotubes|Amino Acid Sequence|Cell Differentiation|Muscle, Skeletal|Gene Expression|Gene Expression Regulation, Developmental|Phylogeny 15 C2CD4A 20818381 Nat. Genet. 2010 10.1038/ng.660 108 0 14 19 Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Japan|SNPs|Asian|Genetic Predisposition to Disease|Case-Control Studies|Genotype|UBE2E2 protein, human|Ubiquitin-Conjugating Enzymes 15 CMTM1 20213316 Mol. Cells 2010 10.1007/s10059-010-0038-7 14 2 2 8 Humans|*HeLa Cells|*Cell Cycle|*M Phase|*Cell Proliferation|cDNA|Amino Acid Sequence|Base Sequence|Green Fluorescent Proteins|Gene Library|Cloning, Molecular|Alternative Splicing|Transfection|Exons|Cytoplasm|Membrane Proteins|Gene Expression Profiling|CMTM4 protein, human|MARVEL Domain-Containing Proteins 15 ERGIC2 20547749 Mol. Cell. Biol. 2010 PMC2916448 10.1128/MCB.00118-10 0 0 7 139 Humans|estrogen receptor alpha, human|*Estrogen Receptor alpha|*Transcriptional Activation|Response Elements|Binding Sites|Estradiol|Chromatin Immunoprecipitation|Transcription, Genetic|*Genome|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|Estrogens|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Protein Binding|DNA 15 FIZ1 20360400 J. Leukoc. Biol. 2010 10.1189/jlb.1109748 3 1 0 41 Mice|Animals|*Interleukin-7|*Retrovirus|STAT5A protein, human|STAT5 Transcription Factor|*Signal Transduction|*Lymphoma, B-Cell|Tumor Suppressor Proteins|*Protein Binding|DNA-Binding Proteins|Trans-Activators|Pro-B-Cells|Phosphorylation|Cell Differentiation|Transcriptional Activation 15 FIZ1 20161818 Mol. Vis. 2010 PMC2822553 15 9 0 41 *RNA Polymerase II|*Transcriptional Activation|Transcription Start Sites|Retinal Rod Photoreceptor Cells|Homeodomain Proteins|Eye Proteins|Trans-Activators|Promoter Regions, Genetic|*Neurogenesis|RNA 15 FIZ1 20047880 Plant Cell Physiol. 2010 10.1093/pcp/pcp189 12 1 0 41 *Arabidopsis|*Actins|*Actin Filament|Arabidopsis Proteins|Plants, Genetically Modified|Golgi Apparatus|Amino Acid Sequence 15 FOXRED1 20858599 Hum. Mol. Genet. 2010 PMC4560042 10.1093/hmg/ddq414 26 0 0 26 Humans|Child|Mitochondrial encephalopathy|*Flavin-Adenine Dinucleotide|Iran|*Mitochondrial Encephalomyopathies|*Electron Transport Complex I|*Molecular Chaperone|Homozygote|*Oxidoreductases|Disorder, Mitochondrial|Mitochondrial Proteins|Pedigree|Mutation|Chain, Respiratory|FOXRED1 protein, human 16 FOXRED1 20818383 Nat. Genet. 2010 PMC2977978 10.1038/ng.659 118 1 6 26 Humans|Electron Transport Complex I|*Mutations|Mitochondrial Diseases|Mitochondrial Proteins|Mitochondria|Amino Acid Sequence|High-Throughput Nucleotide Sequencing|*Metabolism, Inborn Errors|FOXRED1 protein, human|Molecular Chaperones|NUBPL protein, human 16 gal3st1 20624317 Mol. Cancer 2010 PMC2913985 10.1186/1476-4598-9-186 38 3 4 36 Humans|Female|*Sulfoglycosphingolipids|*Transcriptome|*Lipidomics|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization 15 gal3st1 20231363 Mol. Cell. Biol. 2010 PMC2863697 10.1128/MCB.01093-09 27 1 3 36 Male|Mice|Animals|*Testis|galactosylceramide sulfotransferase|*Spermatogenesis|*Sulfotransferases|Promoter Regions, Genetic|DNA-Binding Proteins|CCCTC-Binding Factor|Repressor Proteins|DNA Methylation|Base Sequence|Binding Site|Antigens, Neoplasm|Gene Expression Regulation, Neoplastic|Protein Binding|Cell Line, Tumor|Protein Isoforms 15 MMP27 20473119 Spine 2010 10.1097/BRS.0b013e3181c0c727 9 0 0 4 Cattle|Animals|*Chondrocytes|*Nucleus Pulposus|*Intervertebral Disc|*Gene Expression Profiling|Tissue Inhibitor of Metalloproteinases|Cartilage, Articular|Matrix Metalloproteinases|*Microarray Analysis|Cells, Cultured 15 NAA25 20089178 BMC Med. Genet. 2010 PMC2830196 10.1186/1471-2350-11-11 5 1 0 77 Humans|*Diabetes Mellitus, Type 1|Estonia|PTPN22 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 22|*Alleles|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Genotype|Antigens, Differentiation, T-Lymphocyte|Case-Control Studies|European Continental Ancestry Group 15 NDNF 20969804 BMC Neurosci 2010 PMC2984559 10.1186/1471-2202-11-137 16 1 0 53 Animals|Mice|Drosophila melanogaster|enovin|*Nerve Growth Factors|NTF3 protein, human|*Neurons|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Cell Differentiation|Cells, Cultured 15 PPP1R14C 20592344 Anticancer Res. 2010 1 0 0 90 Mice|Humans|Rats|Animals|*Protein Phosphatase 1|*Epitopes|phosphoprotein phosphatase inhibitor 1|Hybridoma|Epitope Mapping|Antibodies, Monoclonal|Amino Acid Sequence|Blotting, Western|protein phosphatase inhibitor-1|*Intracellular Signaling Peptides and Proteins|BALB C Mice|ELISA|Peptides|Immunoblotting 15 RSRC1 20600988 Neuroimage 2010 PMC3055795 10.1016/j.neuroimage.2010.06.036 47 9 2 134 Humans|Animals|Mice|Genome-Wide Association Study|*Gene Regulatory Networks|Nerve Tissue Proteins|Receptors, Immunologic|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|Prefrontal Cortex|Brain|Neuroimaging|Working Memory|CTXN3 protein, human|Membrane Proteins|ARHGAP18 protein, human|GTPase-Activating Proteins|Robo2 protein, mouse|ARHGAP18 protein, mouse 15 SLC22A24 20865662 Histol. Histopathol. 2010 10.14670/HH-25.1385 9 0 1 1 Rats|Mice|Animals|Female|Male|Humans|Sexual Maturation|*Kidney|*Organic Anion Transporters|*Sex Differences|Rats, Wistar|Dicarboxylic Acid Transporters|Kidney Tubules, Proximal|Western Blotting|Ovariectomy|Gonadal Steroid Hormones|mRNA|Orchiectomy|Brush Border|OAT5 protein, rat 15 SLC22A24 20407758 Arch. Toxicol. 2010 10.1007/s00204-010-0541-9 5 0 0 1 Male|Rats|Animals|*Mercuric Chloride|*Mercury|*Rats, Wistar|*Kidney|Dicarboxylic Acid Transporters|Organic Anion Transporters, Sodium-Dependent|Kidney Function Tests|Acute Kidney Injury|*Biomarkers|Western Blotting|Symporters|Kidney Tubules, Proximal|OAT5 protein, rat 15 SLC25A31 20060930 Int. J. Biochem. Cell Biol. 2010 10.1016/j.biocel.2009.12.024 8 7 0 20 Humans|*Mitochondria|*Apoptosis|Mitochondrial ADP, ATP Translocases|Proto-Oncogene Proteins c-bcl-2|lonidamine|Indazoles|*Adenine Nucleotides|HeLa Cells|*Isoforms|Staurosporine|Cell Proliferation|Cytosol 15 SSH2 20477815 APMIS 2010 10.1111/j.1600-0463.2010.02612.x 5 0 0 99 Humans|*Microsatellite Instability|*Phosphatase, Dual-Specificity|*Tyrosine|*DNA Mutational Analysis|Mutations, Frameshift|Colorectal Cancer|Gastric Cancers|Polymorphism, Single-Stranded Conformational|*Stomach|DNA, Neoplasm|Mutations|*Colonic Neoplasms|Exons|Colon|CDC14A protein, human|Phosphoric Monoester Hydrolases 15 SSH2 20171024 Vet. Microbiol. 2010 10.1016/j.vetmic.2010.01.023 8 0 0 99 Swine|Animals|*Haemophilus parasuis|*Virulence|*Subtractive Hybridization Techniques|Haemophilus Infections|Swine Diseases|Serotyping|Serovars|DNA, Bacterial|PCR|Gene Library|Nucleic Acid Hybridization 15 TCFL5 20935203 J. Immunol. 2010 PMC2959144 10.4049/jimmunol.1002197 27 4 5 661 Humans|*HIV-1|*Lymphatic Tissue|Viral Load|Virus Replication|HIV Infections|RNA, Viral|*HIV Seropositivity|Gene Expression Profiling|Lymph Nodes|POSTN protein, human|Cell Adhesion Molecules|ZNF148 protein, human|DNA-Binding Proteins|Transcription Factors|CREBZF protein, human|Basic-Leucine Zipper Transcription Factors 15 ZNF219 20940257 J. Cell. Sci. 2010 10.1242/jcs.071373 15 7 2 67 *Chondrogenesis|*Chondrocytes|SOX9 protein, human|*SOX9 Transcription Factor|*Cell Differentiation|*Gene Expression Regulation|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Transforming Growth Factor beta|Transcription, Genetic|Promoter Regions, Genetic|Cell Line|BMP2 protein, human|mRNA|Aggrecan|Cells, Cultured|Reporter Gene 15 ZNF81 20662849 Clin. Genet. 2010 10.1111/j.1399-0004.2010.01496.x 6 0 1 22 Male|Humans|Female|Child|Mental Retardation, X-Linked|Sex Chromosome Aberrations|Chromosomes, Human, X|Gene Duplication|Comparative Genomic Hybridization|Phenotype|Intellectual Disability|In Situ Hybridization, Fluorescence|*Cognition 15 ZNF81 20186789 Am. J. Med. Genet. A 2010 10.1002/ajmg.a.33292 2 0 0 22 Humans|Male|*Intellectual Disability|Mental Retardation, X-Linked|Chromosomes, Human, X|Pedigree|Gene Dosage|Gene Deletion|Mutations|*Chromosome Structures|Zinc Finger|Australia|Brazil|Europe 15 AKIRIN1 19406121 Exp. Cell Res. 2009 10.1016/j.yexcr.2009.04.014 17 1 0 132 *Chemotaxis|MSTN protein, human|Myostatin|Satellite Cells, Skeletal Muscle|Myotube|Muscle, Skeletal|Regeneration|Transforming Growth Factor beta|Cell Division 15 AKIRIN1 19200367 BMC Evol. Biol. 2009 PMC2660306 10.1186/1471-2148-9-34 25 38 2 132 Animals|Mice|*Eukaryotes|Evolution, Molecular|Synteny|Phylogeny|Gene Duplication|Multigene Family|Sequence Alignment|Introns|Amino Acid Sequence|*Eukaryotic Cells|Nuclear Proteins|Drosophila 15 DUSP11 19228121 Biochem. J. 2009 10.1042/bj20082234 249 4 21 83 *Dual-Specificity Phosphatases|Mitogen-Activated Protein Kinase Phosphatases|c-jun N-Terminal Kinase|Protein Phosphatases|Signal Transduction|MAP Kinase Signaling System|Extracellular Signal Regulated Kinases|Phosphorylation|Phosphotyrosine|Substrate Specificity|RASGRF1 protein, human|ras-GRF1 15 DUSP11 19120688 J. Cell. Mol. Med. 2009 PMC6529972 10.1111/j.1582-4934.2008.00616.x 4 6 0 83 *Tumor Suppressor Protein p53|DNA Damage|Blotting, Northern|Apoptosis|Genes, p53|shRNA|Gene Expression Regulation, Neoplastic|Protein Tyrosine Phosphatase|Binding Sites|Cell Cycle Proteins|Cell Line, Tumor|Blotting, Western 15 FGGY 20001489 Amyotroph Lateral Scler 2009 10.3109/17482960903358857 8 0 0 8 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Canada|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|Potassium Channels|Genome, Human|Nerve Tissue Proteins|Cohort Studies|Mutations|France|Quebec|DPP6 protein, human 15 FGGY 19922138 Amyotroph Lateral Scler 2009 10.3109/17482960802673042 8 0 0 8 Humans|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Genome-Wide Association Study|*Risk Factors|SNPs|Genetic Predisposition to Disease|Case-Control Studies|Genetics, Population|European Continental Ancestry Group|DNA Mutational Analysis|Ireland|Netherlands|Northern Europe|Belgium|Sweden 15 FGGY 19193627 Hum. Mol. Genet. 2009 PMC2664150 10.1093/hmg/ddp059 42 0 4 8 Humans|*Genome-Wide Association Study|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|SNPs|Linkage Disequilibrium|Genetic Predisposition to Disease|Genome, Human|Genotype|Case-Control Studies|Cohort Studies|Odds Ratio 15 FIZ1 19880182 Leuk. Res. 2009 10.1016/j.leukres.2009.10.004 16 1 2 41 Humans|*Calcitriol|dihydroxy-vitamin D3|*Vitamin D|VDR protein, human|Vitamin D Receptor|*Leukemia, Myeloid, Acute|*Cell Differentiation|HL-60 Cells|1,25-dihydroxyergocalciferol|Ergocalciferols|*Mutations|Antineoplastic Agents 15 IGSF10 19444910 Int. J. Cancer 2009 10.1002/ijc.24392 14 0 3 19 Rats|Animals|Glycogen Synthase Kinase 3 beta|CTNNB1 protein, human|beta Catenin|Osteosarcoma|Wnt Proteins|*Gene Expression Profiling|DKK3 protein, human|Intercellular Signaling Peptides and Proteins|Cell Differentiation|Wnt beta-Catenin Signaling Pathway|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Phosphorylation|AKAP12 protein, human|A Kinase Anchor Proteins|Cell Proliferation|Cell Cycle Proteins 15 NAA25 19565500 Arthritis Rheum. 2009 PMC3104295 10.1002/art.24618 28 7 2 77 *Arthritis, Juvenile|*STAT4 Transcription Factor|TNFAIP3 protein, human|*Tumor Necrosis Factor alpha-Induced Protein 3|Genetic Susceptibility|Polymorphism, Single Nucleotide|Rheumatoid Arthritis|Alleles|Gene Frequency|TNF Receptor-Associated Factor 1|Genotype|Case-Control Studies|Phenotypes 15 NDNF 19258215 Eur. J. Med. Res. 2009 PMC3351962 10.1186/2047-783x-14-2-65 0 2 0 53 Humans|Mice|Animals|*Fenofibrate|*Microcirculation|*Diabetes Mellitus, Experimental|*Wound Healing|PPARalpha|Hypolipidemic Agents|Skin|Blood Sugar 15 PFN3 19419568 BMC Cell Biol. 2009 PMC2694148 10.1186/1471-2121-10-34 10 11 0 11 Animals|Male|PFN1 protein, human|*Profilins|*Spermatids|*Testis|Contractile Proteins|*Cytoskeleton|Microfilament Proteins|Actins|Isoforms|Amino Acid Sequence|Protein Binding|Binding Sites 15 PFN3 19237395 Nucleic Acids Res. 2009 PMC2673434 10.1093/nar/gkp088 21 1 1 11 Male|Mice|Animals|*siRNA|*Transporter, Phosphate|RNA Interference|RNA, Antisense|*RNA, Double-Stranded|Gene Expression Regulation|Genome|Northern Blotting|Slc34a1 protein, mouse|Sodium-Phosphate Cotransporter Proteins, Type IIa 15 PPP1R14C 19846560 J. Biol. Chem. 2009 PMC2790955 10.1074/jbc.R109.059972 63 5 7 90 *Protein Phosphatase 1|*Phosphorylation|cyclopropapyrroloindole|Indoles|phosphoprotein phosphatase inhibitor 1|Myosin-Light-Chain Phosphatase|protein phosphatase inhibitor-1|Intracellular Signaling Peptides and Proteins|phosphatase-1 kinase|Protein Kinases|Phosphoproteins|Muscle Proteins 15 PPP1R14C 19819304 Neuroscience 2009 PMC3170095 10.1016/j.neuroscience.2009.10.007 9 15 3 90 Mice|Animals|*Morphine|*Quantitative Trait Loci|*Mice, Inbred C57BL|*Drug Tolerance|OPRM1 protein, human|Receptor, mu Opioid|*Analgesia|*Pain|Analgesics, Opioid|*Pain Management|Mice, Knockout|Pain Measurement|Analgesics|Phosphorylation|Reward 15 PPP1R14C 19132087 PLoS Genet. 2009 PMC2607021 10.1371/journal.pgen.1000319 82 10 5 90 Child|Humans|*Genome-Wide Association Study|*Mucocutaneous Lymph Node Syndrome|SNPs|Genetic Predisposition to Disease|Linkage Disequilibrium|Allele Frequency|Genetic Loci|Asian Continental Ancestry Group|Haplotypes|Genotype|Chromosome Mapping|European Continental Ancestry Group|Cohort Studies 15 SLC22A24 19538982 Toxicol. Appl. Pharmacol. 2009 10.1016/j.taap.2009.06.008 7 4 2 1 Male|Rats|Animals|*Organic Anion Transporters|ochratoxin A|*Upregulation|Organic Anion Transport Protein 1|*Kidney Cortex|ochratoxin B|*Ochratoxins|Organic Anion Transporters, Sodium-Independent|Kidney|Kidney Tubules, Proximal|Kidney Medulla|mRNA|*Cerebral Cortex|*Transcriptional Activation|OAT5 protein, rat|Dicarboxylic Acid Transporters 15 SLC25A31 19556438 Reproduction 2009 PMC3727218 10.1530/REP-09-0201 21 1 1 20 Male|Mice|Animals|Meiosis|Spermatogenesis|Spermatocytes|Testis|Meiotic Prophase I|SYCP1 protein, human|Nuclear Proteins|Synapsis, Chromosomal|Spermatozoa|DNA Breaks, Double-Stranded|DNA Repair|Mitochondrial ADP, ATP Translocases 15 SMR3B 19834740 J. Cancer Res. Clin. Oncol. 2009 10.1007/s00432-009-0695-0 8 0 0 14 *Carcinoma, Hepatocellular|*Osteopontin|*Liver Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Genomics|Transfection 15 TP53I11 19333544 J. Gastroenterol. 2009 10.1007/s00535-009-0030-1 2 2 0 22 Humans|*Arsenic Trioxide|Carcinoma, Hepatocellular|*Tumor Suppressor Protein p53|Liver Neoplasms|Arsenicals|Apoptosis|*Carcinogenesis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Oxides|Gastric Cancer|*Cell Death|Genes, Tumor Suppressor 15 ZBTB7C 19538736 BMC Dev. Biol. 2009 PMC2711087 10.1186/1471-213X-9-36 40 4 2 57 Humans|Male|Female|Mice|Animals|*Ovary|*Forkhead Box Protein L2|*Sex Differentiation|WNT4 protein, human|Wnt4 Protein|Sex Determination Processes|Testis|Forkhead Transcription Factors|Disorders of Sex Development|Gene Expression Regulation, Developmental|FOXL2 protein, human|Foxl2 protein, mouse 15 ZNF219 19549856 Proc. Natl. Acad. Sci. U.S.A. 2009 PMC2708714 10.1073/pnas.0901591106 32 7 1 67 *Wnt Signaling Pathway|CTNNB1 protein, human|beta Catenin|Wnt Proteins|TCF Transcription Factors|*Genome|Binding Site|Promoter Regions, Genetic|Transcription Factors|Protein Binding|*Nephroblastoma|Chromatin Immunoprecipitation|Base Sequence|Gene Expression Regulation, Neoplastic|Kidney Neoplasms 15 ZNF219 19549071 J. Neurochem. 2009 10.1111/j.1471-4159.2009.06250.x 17 0 0 67 Animals|Rats|*alpha-Synuclein|*Gene Expression Regulation|*Promoter Regions, Genetic|Zinc Finger|Neurons|Transcription, Genetic|Kruppel-Like Transcription Factors|Binding Sites|Signal Transduction|Parkinson Disease|Intron 15 AKIRIN1 19041667 Dev. Comp. Immunol. 2008 10.1016/j.dci.2008.11.002 21 0 1 132 Animals|Mice|Phylogeny|subolesin, tick|*Arthropod Proteins|*Antigens|Ticks|*Vertebrates|*Insects|RNA Interference|Proteins|Akirin2 protein, mouse|Repressor Proteins 15 ARPP21 18786617 Neuroscience 2008 PMC2629946 10.1016/j.neuroscience.2008.07.070 31 0 2 59 Mice|Animals|*Central Amygdala|*Transcriptome Analysis|Bed Nucleus of Stria Terminalis|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation|Nucleus Accumbens|In Situ Hybridization|Nerve Tissue Proteins|Gpr88 protein, mouse|Receptors, G-Protein-Coupled|Rem2 protein, mouse|Monomeric GTP-Binding Proteins 15 FIZ1 18854042 BMC Mol. Biol. 2008 PMC2571102 10.1186/1471-2199-9-87 8 25 0 41 Animals|Mice|*Transcription Factors|Rod Photoreceptor|Homeodomain Proteins|Trans-Activators|Retina|Promoter Regions, Genetic|Activation, Transcriptional|Eye Proteins|Rhodopsin|Transcription, Genetic|Basic-Leucine Zipper Transcription Factors|Zinc Finger|RNA, Messenger 15 FIZ1 18628457 Clin. Cancer Res. 2008 10.1158/1078-0432.CCR-07-1873 5 3 0 41 Humans|*Tyrosine|FLT3 protein, human|*fms-Like Tyrosine Kinase 3|*Oncogenes|*Oncogenesis|Leukemia, Myeloid, Acute|Phosphorylation|Tyrosine Kinase|Signal Transduction|Mutations|STAT5 Transcription Factor|Cell Transformation, Neoplastic|*Ligands|Amino Acid Sequence|Mutagenesis, Site-Directed|Cell Division 15 FUBP3 19087307 BMC Cancer 2008 PMC2631590 10.1186/1471-2407-8-369 19 12 2 105 Humans|Male|*Urinary Bladder Neoplasms|*Prostate|FUBP1 protein, human|*RNA-Binding Proteins|Carcinoma, Renal Cell|Kidney Neoplasms|Genes, myc|Proto-Oncogene Proteins c-myc|Gene Expression Regulation, Neoplastic|Prostatic Neoplasms|Biomarkers, Tumor|*Kidney 15 gal3st1 18716796 Parasitol. Res. 2008 10.1007/s00436-008-1152-8 12 0 1 36 Rats|Animals|*Nippostrongylus|*Sulfotransferases|sulfomucin|*Mucin|Sialomucin|*Intestinal Epithelium|MUC1 protein, human|*Mucin-1|Goblet Cells|Jejunum|Strongylida Infections|T Cells 15 gal3st1 18683247 J. Neurosci. Res. 2008 PMC2606914 10.1002/jnr.21822 28 1 1 36 *Schizophrenia|Oligonucleotide Array|Antipsychotic Agents|Cortex, Prefrontal|Gene Expression Profiling|Gene Expression|Signal Transduction|Oligodendrocyte|Real-Time Polymerase Chain Reaction|Sphingolipids 15 PFN3 18550648 J. Am. Soc. Nephrol. 2008 PMC2518441 10.1681/ASN.2007121360 10 0 0 11 Humans|Mice|Animals|sodium phosphate|*Mutation, Missense|Sodium-Phosphate Cotransporter Proteins, Type IIa|Phosphates|Hypophosphatemia|Sodium-Phosphate Cotransporter Proteins|*Homeostasis|Kidney|Hypercalcemia|Kidney Calculi|Calcium|Opossum|SLC34A1 protein, human|Slc34a1 protein, mouse 15 PPP1R14C 18803327 Genes Chromosomes Cancer 2008 10.1002/gcc.20615 30 1 1 90 *Promoter Regions, Genetic|DNA Methylation|5AzadC|CpG Islands|Azacitidine|trichostatin A|Hydroxamic Acids|DNA Modification Methylases|Genes, Tumor Suppressor|*Melanoma|Gene Silencing|Histones|Tumor Suppressor Proteins|AKAP12 protein, human|Cell Cycle Proteins|Nuclear Proteins|Enzyme Inhibitors|A Kinase Anchor Proteins 15 RSRC1 19065146 Mol. Psychiatry 2008 PMC3254586 10.1038/mp.2008.127 45 9 0 134 15 SLC22A24 18796410 J. Histochem. Cytochem. 2008 PMC2605716 10.1369/jhc.2008.951582 8 0 0 1 Male|Rats|Animals|*Rats, Wistar|*Kidney|Dicarboxylic Acid Transporters|Organic Anion Transporters, Sodium-Dependent|Kidney Function Tests|Symporters|Western Blotting|Biomarkers|Reperfusion Injury|OAT5 protein, rat 15 SLC25A31 18667754 Biol. Reprod. 2008 PMC2715002 10.1095/biolreprod.108.067645 17 0 0 20 Mice|Animals|*Meiosis|Promoter Regions, Genetic|E2F6 Transcription Factor|Transcription Factors|Chromatin Immunoprecipitation|DNA Methylation|Binding Sites|Cell Cycle Proteins|Gene Silencing 15 SMR3B 18717013 Cancer Biol. Ther. 2008 10.4161/cbt.7.3.5365 4 1 0 14 *Carcinoma, Hepatocellular|*Osteopontin|*Liver Neoplasms|Comparative Genomic Hybridization|Cell Line, Tumor|*Genetic Profile|Genes, Neoplasm|Cell Proliferation|Genomics 15 SSH2 18171679 J. Biol. Chem. 2008 10.1074/jbc.M706538200 18 1 1 99 Rats|Animals|LIMK1 protein, human|*Lim Kinases|*Ascites|*Carcinoma, Hepatocellular|Actin Depolymerizing Factor|Actin Depolymerizing Factors|Actin|Microfilament Proteins|Filaments, Actin|Phosphorylation|Protein Phosphatases|Protein Kinases|Cell Movement|Cytoskeleton|Liver Neoplasms 15 TCFL5 18829976 Gut 2008 10.1136/gut.2007.143065 0 0 5 661 *Adenoma|*Colorectal Neoplasms|*Oncogenes|*Neoplastic Processes|DNA, Neoplasm|Chromosome Aberrations|Disease Progression|Chromosomes 15 TCFL5 18652679 BMC Immunol. 2008 PMC2503978 10.1186/1471-2172-9-39 41 52 1 661 Humans|*Toll-Like Receptor 7|*Toll-Like Receptor 9|*Lymphocyte Activation|B Cells|Plasmacytoid Dendritic Cells|Oligodeoxyribonucleotides|Cell Differentiation|Interferon-alpha|Signal Transduction|TLR7 protein, human|TLR9 protein, human 15 TP53I11 19096915 Pathol. Oncol. Res. 2008 10.1007/s12253-008-9138-5 10 0 2 22 Humans|*Carcinoma, Hepatocellular|*Hep G2 Cells|*Liver Neoplasms|*Apoptosis|*Carcinogenesis|Downregulation|Cell Line, Tumor|Neoplasm Proteins|Liver|Transfections|Cell Proliferation 15 ZNF219 18776481 Nucleic Acids Symp Ser (Oxf) 2008 10.1093/nass/nrn262 0 0 0 67 Humans|*DNA|*Catalysis|Nucleic Acid Conformation|DNA, Catalytic|DNA, Single-Stranded|Ions|cDNA|Kinetics|PCR 15 AKIRIN1 18066067 Nat. Immunol. 2007 PMC2680477 10.1038/ni1543 64 7 3 132 Humans|Mice|Animals|*Drosophila|*NF-kappa B|*Nuclear Proteins|Drosophila melanogaster|*Mice, Knockout|Drosophila Proteins|RELA protein, human|*Transcription Factor RelA|Toll-Like Receptor|Signal Transduction|Innate Immune Response|RNA Interference|*Gene Expression 15 CMTM1 17657266 Beijing Da Xue Xue Bao 2007 2 0 0 8 Humans|Male|AR protein, human|*Receptors, Androgen|Prostatic Neoplasms|Prostate|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Co-Repressor Proteins 15 ERGIC2 18079591 Endocr. J. 2007 10.1507/endocrj.k07e-030 4 0 0 139 Female|Humans|Adult|*Pituitary Neoplasms|*Adrenocorticotropic Hormone|*Prolactin|*Transcription Factors|Adenoma|*Pituitary Hormones, Anterior|Immunohistochemistry|RNA, Messenger 15 ERGIC2 18074675 Oncol. Res. 2007 10.3727/000000007783980873 7 1 0 139 *Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Carcinoma|RNA Interference|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Chromosome Structures 15 ERGIC2 17980171 Biochim. Biophys. Acta 2007 10.1016/j.bbapap.2007.10.006 1 4 0 139 EEF1A2 protein, human|EEF1A1 protein, human|*Peptide Elongation Factor 1|Carcinoma, Hepatocellular|Proteomics|Liver Neoplasms|Translation, Protein|Protein Binding|Cell Proliferation|Western Blotting|Cell Lines|Apoptosis 15 ERGIC2 17761669 J. Biol. Chem. 2007 10.1074/jbc.M705558200 11 1 0 139 Animals|Rabbits|beta-Peptide, Amyloid|APP protein, human|Amyloid beta-Protein Precursor|Neurons|Peptide Fragments|Cultured Cells|Apoptosis|Phosphorylation|*Cell Death|Brain|Cell Line|Protein Kinase C 15 ERGIC2 17478929 Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007 0 2 0 139 *RNA Interference|*Nasopharyngeal Carcinoma|pectenotoxin 1|Nasopharyngeal Neoplasms|RNA, Small Interfering|Cell Line, Tumor|Transfection|RNA, Messenger|Gene Expression Regulation, Neoplastic|Apoptosis 15 PFN3 17668047 PLoS ONE 2007 PMC1924603 10.1371/journal.pone.0000659 24 4 1 11 Humans|*Fusobacterium nucleatum|*Fusobacterium|Fusobacterium Infections|*Base Sequence|RNA, Ribosomal, 16S|DNA, Bacterial|Sequence Analysis, DNA|*Chromosome Mapping 15 PPP1R14C 17516844 Biol. Chem. 2007 10.1515/BC.2007.062 5 1 1 90 Humans|*MAP Kinase Signaling System|*Protein Phosphatase 1|*Downregulation|PTEN protein, human|PTEN Phosphohydrolase|phosphoprotein phosphatase inhibitor 1|*MCF7 Cells|Signal Transduction|Mitogen-Activated Protein Kinase Kinases|protein phosphatase inhibitor-1|*Intracellular Signaling Peptides and Proteins|Extracellular Signal-Regulated MAP Kinases|Phosphorylation|Cell Line, Tumor|Up-Regulation|U 0126|Butadienes|Gene Expression Regulation, Neoplastic 15 PPP1R14C 17512813 Eur J Med Genet 2007 10.1016/j.ejmg.2007.03.003 6 0 1 90 Child|Humans|Female|Chromosome Deletion|Abnormalities, Multiple|*Heart Septal Defects|Craniofacial Abnormalities|*Failure to Thrive|Heart Defects, Congenital|Developmental Disabilities|Intellectual Disability|Karyotyping|Phenotype|Syndrome|Oligonucleotide Array Sequence Analysis 15 SLC22A24 17714910 Genomics 2007 10.1016/j.ygeno.2007.03.017 30 0 3 1 Rats|Animals|Humans|Mice|Phylogeny|*Biological Transport|*Membrane Transport Proteins|Amino Acid Sequence|Sequence Homology, Amino Acid|Vertebrate|Ion Transport|SLC22A23 protein, human|Organic Anion Transporters 15 SSH2 17848544 J. Biol. Chem. 2007 PMC2754063 10.1074/jbc.M707041200 37 5 1 99 Humans|*Keratinocytes|*Phosphorylation|*Laminin|*Cell Migration|Actin Depolymerizing Factors|*Microfilament Proteins|beta4 Integrin, alpha6|rac1 GTP-Binding Protein|Actins|kalinin|*Cell Adhesion Molecules|Signal Transduction|Epidermal Cell|Phosphoprotein Phosphatases|Cell Polarity|14-3-3 Proteins|RAC1 protein, human 15 SSH2 17360713 J. Biol. Chem. 2007 10.1074/jbc.M610873200 51 7 3 99 Rats|Animals|LIMK2 protein, human|LIMK1 protein, human|*Lim Kinases|*Neurites|Actin Depolymerizing Factor|Actin Depolymerizing Factors|Microfilament Proteins|Phosphorylation|Actins|Protein Kinases|Growth Cone|Actin Cytoskeleton|Cell Movement|Neurons|Dorsal Root Ganglion|*Neurogenesis|Nerve Growth Factors|Limk2 protein, rat 15 TCFL5 17956600 BMC Genomics 2007 PMC2211320 10.1186/1471-2164-8-385 20 4 1 661 Child|Humans|RUNX1 protein, human|TEL-AML1 fusion protein|*Core Binding Factor Alpha 2 Subunit|*Oncogene Proteins, Fusion|Translocation, Genetic|Precursor Cell Lymphoblastic Leukemia-Lymphoma|In Situ Hybridization, Fluorescence|Polymerase Chain Reaction|Burkitt Lymphoma|*Biological Processes 15 TP53I11 17482569 Biochem. Biophys. Res. Commun. 2007 10.1016/j.bbrc.2007.04.048 2 0 0 22 *DNA|Nucleic Acid Conformation|Plasmid|DNA, Superhelical|Atomic Force Microscopy|TP53 protein, human|Tumor Suppressor Protein p53|TYRP1 protein, human|*Membrane Glycoproteins|Protein Binding|Circular DNA|*Biophysical Phenomena|Apoptosis 15 ZBTB7C 17932560 Mol. Med. 2007 PMC2014730 10.2119/2007-00113.Zhou 7 0 0 57 15 CMTM1 17002874 J. Biochem. Mol. Biol. 2006 10.5483/bmbrep.2006.39.5.537 5 0 1 8 Humans|Male|Mice|Rats|Animals|MARVEL Domain-Containing Proteins|Chemokines|Cell Proliferation|Real-Time PCR, Quantitative|Testis|CMTM3 protein, human 15 DUSP11 17164780 Mol. Ther. 2006 10.1038/sj.mt.6300003 14 0 1 83 Humans|*HT 29 Cells|*Spheroids, Multicellular|*Colonic Neoplasms|Tumor Cell Lines|Gene Expression Regulation, Neoplastic|Kruppel-Like Transcription Factors|Cell Proliferation|Signal Transduction|Short Interfering RNA|Colon|DUSP11 protein, human|Dual-Specificity Phosphatases 15 ERGIC2 16989575 DNA Cell Biol. 2006 10.1089/dna.2006.25.523 4 2 0 139 Humans|Male|*PC3 Cell Line|*Upregulation|*Interferon-beta|pectenotoxin 1|*Prostate Cancer|Prostate|Homeodomain Proteins|*Transcriptional Activation|Transcription Factors|Nuclear Proteins|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line|Tumor Cells, Cultured|Gene Expression|Endoplasmic Reticulum|Cellular Senescence 15 FIZ1 17141759 Exp. Eye Res. 2006 PMC5066392 10.1016/j.exer.2006.10.009 5 5 0 41 Animals|Mice|*Promoter Regions, Genetic|Retinal Rod Photoreceptor Cells|Rhodopsin|Retina|Homeodomain Proteins|Eye Proteins|Trans-Activators|Transcription Factor|Cyclic Nucleotide Phosphodiesterases, Type 6|Transcription, Genetic|Basic-Leucine Zipper Transcription Factors|Gene Expression Regulation|Zinc Finger|mRNA|Transfection|*Neurogenesis|Nrl protein, mouse 15 FUBP3 16914741 Mol. Cell. Biol. 2006 PMC1592819 10.1128/MCB.00754-06 27 0 1 105 FUBP1 protein, human|poly-U binding splicing factor 60KDa|RNA Splicing Factors|RNA-Binding Proteins|Repressor Proteins|DNA Helicases|Proto-Oncogene Proteins c-myc|Transcription, Genetic|Gene Expression Regulation|Transcription Factor TFIIH|Protein Binding|Activation, Transcription|Amino Acid Sequence|FOLR2 protein, human|*Folate Receptor 2 15 FUBP3 16865290 Int. J. Oncol. 2006 2 0 0 105 Humans|*Medulloblastoma|Cerebellar Neoplasms|FUBP1 protein, human|*DNA-Binding Proteins|*RNA-Binding Proteins|Electrophoresis, Gel, Two-Dimensional|TYRP1 protein, human|*Membrane Glycoproteins|Amino Acid Sequence|Gene, c-myc|Cell Line, Tumor|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Trans-Activators 15 SLC25A31 17137571 Dev. Biol. 2006 PMC1858657 10.1016/j.ydbio.2006.10.004 34 0 3 20 Male|Humans|*Sperm Tail|*Glycolysis|*Sperm|Sperm Motility|Flagellum|SLC25A4 protein, human|*Adenine Nucleotide Translocator 1|Spermiogenesis|Pyruvate Kinase|Adenosine Triphosphate|Mitochondria|Cytoskeleton|Aldolase|Adenosine Diphosphate 15 SMR3B 17080484 Proteomics 2006 10.1002/pmic.200600395 13 0 0 14 Humans|*Saliva|Tandem Mass Spectrometry|Salivary Proteins|Chromatography, High Pressure Liquid|Spectrometry, Mass, Electrospray Ionization|Amino Acid Sequence|Proteomics|Peptide Fragments|Parotid Gland|Protein Processing, Post-Translational 15 SMR3B 16505094 Mol. Cancer Ther. 2006 10.1158/1535-7163.MCT-05-0289 22 1 0 14 Humans|PTP4A3 protein, human|*Endothelial Cells|*Protein Tyrosine Phosphatase|PTP4A1 protein, human|Neoplasm Proteins|Tumor Cell Lines|mRNA|RNA, Small Interfering|Gene Expression Regulation, Neoplastic|Transfection|Cell Movement|Cell Proliferation|Blotting, Western|Oligonucleotide Microarray|Membrane Proteins|Cell Cycle Proteins 15 TCFL5 17164780 Mol. Ther. 2006 10.1038/sj.mt.6300003 14 0 1 661 Humans|*HT 29 Cells|*Spheroids, Multicellular|*Colonic Neoplasms|Tumor Cell Lines|Gene Expression Regulation, Neoplastic|Kruppel-Like Transcription Factors|Cell Proliferation|Signal Transduction|Short Interfering RNA|Colon|DUSP11 protein, human|Dual-Specificity Phosphatases 15 TCFL5 16990763 Leukemia 2006 10.1038/sj.leu.2404396 19 0 2 661 Humans|*T-Lymphocytes|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Receptor, Notch1|Signal Transduction|Homeodomain Proteins|Receptors, Notch|*Gene, A|Cell Lineage|Hematopoietic Stem Cells|Gene Expression Regulation, Developmental|Promoter Regions, Genetic|NRARP protein, human|Neoplasm Proteins 15 TCFL5 16397242 Cancer Res. 2006 10.1158/0008-5472.CAN-05-2936 42 0 2 661 Male|Humans|Aged|*Seminoma|*Spermatocytes|Comparative Genomic Hybridization|Testicular Neoplasms|Neoplasms, Germ Cell and Embryonal|POU5F1 protein, human|Octamer Transcription Factor-3|Genes, Homeobox|Oligonucleotide Array Sequence Analysis|*Chromosome 9|Gene Expression Profiling|*Genomics|In Situ Hybridization|*Tumorigenesis|Testis|Gene Expression Regulation, Neoplastic|Immunohistochemistry|Karyotyping 15 ZBTB7C 17166701 Mech. Dev. 2006 PMC1847367 10.1016/j.mod.2006.10.004 3 0 0 57 Male|Mice|Animals|*Testis|*Retinoic Acid|Spermatids|Spermatogenesis|Spermatocytes|Receptors, Retinoic Acid|Blotting, Northern|Transcription, Genetic|RNA, Messenger|Retinoids|Vitamin A|Gene Expression Regulation, Developmental|Zinc Finger 15 ZNF81 16506138 Rev Neurol 2006 1 0 0 22 Humans|*Intellectual Disability|*Mental Retardation, X-Linked|Genetic Linkage|*Genes, X-Linked|Chromosomes, Human, X|Chromosome Mapping|Pedigree|Mutation 15 FIZ1 15980254 Invest. Ophthalmol. Vis. Sci. 2005 10.1167/iovs.05-0129 13 16 0 41 *Transcription Factors|LIF protein, human|*Leukemia Inhibitory Factor|Homeodomain Proteins|Photoreceptor Cells, Vertebrate|Eye Proteins|Cell Differentiation|Trans-Activators|Retina|Gene Expression Regulation, Developmental|Basic-Leucine Zipper Transcription Factors|*Neurogenesis|RNA, Messenger 15 MMP27 16238105 Biol. Res. 2005 10.4067/s0716-97602005000200016 7 0 0 4 Humans|Male|Rats|Animals|*Matrix Metalloproteinases|matrix metalloproteinase 25|Matrix Metalloproteinases, Membrane-Associated|Matrix Metalloproteinase 2|Tissue Inhibitor of Metalloproteinase-2|Tissue Inhibitor of Metalloproteinase-1|Matrix Metalloproteinase 9|mRNA|Gene Expression|GPI-Linked Proteins|Extracellular Matrix 15 PPP1R14C 15837133 Neuroscience 2005 10.1016/j.neuroscience.2004.11.052 5 3 1 90 Mice|Animals|Rats|Rabbits|Brain|Neurons|Spinal Cord|*Phosphoric Monoester Hydrolases|Hippocampus|Ganglia, Dorsal Root|Hypothalamus|Thalamus|RNA, Messenger|Morphine|Protein Kinase C 15 RUSC2 15796781 BMC Cell Biol. 2005 PMC1079803 10.1186/1471-2121-6-15 7 16 0 57 Golgi Apparatus|Endoplasmic Reticulum|rab1 GTP-Binding Proteins|Golgi Matrix Proteins|Vesicular Transport Proteins|Membrane Proteins|Carrier Proteins|Protein Transport|Protein Binding|Cell Membrane|Biological Transport|Protein Structure, Tertiary|Protein Isoforms|Two-Hybrid System Techniques|Amino Acid Sequence|Cell Line 15 SLC22A24 16079298 J. Pharmacol. Exp. Ther. 2005 10.1124/jpet.105.088583 23 7 1 1 Rats|Animals|*Tubules, Proximal Renal|Organic Anion Transporters, Sodium-Independent|Organic Anion Transporters|Biological Transport|ochratoxin A|Ochratoxins|Kidney|*Cell Membrane|estrone sulfate|Estrone|Xenopus laevis|Carrier Proteins|Amino Acid Sequence|mRNA|Oocytes|OAT5 protein, rat|Dicarboxylic Acid Transporters 15 TP53I11 15757668 FEBS Lett. 2005 10.1016/j.febslet.2005.02.033 22 0 0 22 *Phytoestrogens|*Oligonucleotide Array Sequence Analysis|ipriflavone|Isoflavones|glycitein|biochanin A|Genistein|daidzein|*Estrogens|Coumestrol|Estradiol|Gene Expression Profiling|Estrogen Receptor beta|naringenin|Flavanones|Soy Beans|Gene Expression|chrysin 15 ZNF81 16385466 Am. J. Hum. Genet. 2005 PMC1380234 10.1086/500306 25 2 1 22 Humans|Comparative Genomic Hybridization|Mental Retardation, X-Linked Nonsyndromic|*Mental Retardation, X-Linked|*Zinc Finger|Chromosomes, Human, X|Genetic Linkage|Pedigree|Mental Retardation|Mutation|Kruppel-Like Transcription Factors|Retinal Dystrophy|Bacterial Artificial Chromosome|Zinc 15 C2CD4A 15527968 Gene 2004 10.1016/j.gene.2004.07.027 29 2 2 19 Humans|*Endothelial Cells|Nuclear Factor-Kappab|TNF protein, human|Tumor Necrosis Factor alpha|IL1B protein, human|Interleukin-1beta|I-kappa B Proteins|*Inflammation|Transcription Factors|Transfection|Promoter Regions, Genetic|Signal Transduction|Transcriptional Activation|Cell Line 15 FIZ1 15304385 Blood 2004 10.1182/blood-2003-10-3381 29 1 0 41 Humans|Adult|*Cytarabine|*Sunitinib|*Daunorubicin|*Fetal Liver Kinase-3|*Tyrosine|Antineoplastic Agents|Leukemia, Myeloid, Acute|Apoptosis|Indoles|Protein Kinase Inhibitors|Cell Line, Tumor|Tyrosine Kinase|Drug Synergism|Phosphorylation|Mutations|FLT3 protein, human 15 GRID2IP 15375526 Oncol. Rep. 2004 18 0 0 15 Humans|Mice|Animals|Base Sequence|Amino Acid Sequence|Chromosome Mapping|Sequence Alignment|Exons|Bioinformatics|Sequence Homology, Amino Acid|Introns|cDNA|Expressed Sequence Tags|Carrier Proteins|Alternative Splicing|*In Silico|Membrane Proteins|DIAPH1 protein, human|Formins|FMNL2 protein, human|FMNL3 protein, human 15 GRID2IP 15289902 Int. J. Mol. Med. 2004 2 0 0 15 Humans|Mice|Animals|Base Sequence|Amino Acid Sequence|Sequence Alignment|Chromosome Mapping|Exon|Bioinformatics|Intron|Sequence Homology, Amino Acid|Carrier Proteins|cDNA|Expressed Sequence Tags|Alternative Splicing|*Human Chromosome|*Chromosome Structures|Genome, Human|DIAPH1 protein, human|Formins|FMNL2 protein, human 15 GRID2IP 15202026 Int. J. Mol. Med. 2004 2 1 0 15 Humans|Mice|Animals|Base Sequence|Amino Acid Sequence|Chromosome Mapping|Exons|Sequence Alignment|Bioinformatics|Protein Isoforms|Alternative Splicing|Introns|Sequence Homology, Amino Acid|cDNA|Expressed Sequence Tags|Carrier Proteins|Codon|*In Silico|Protein Binding|Genes, Regulator|Promoter Regions, Genetic 15 GRID2IP 15138637 Int. J. Mol. Med. 2004 4 0 0 15 Mice|Humans|Animals|*Zebrafish|Amino Acid Sequence|Exons|Base Sequence|Sequence Alignment|Bioinformatics|Chromosome Mapping|Sequence Homology, Amino Acid|Introns|cDNA|Carrier Proteins|Expressed Sequence Tags|Alternative Splicing|*Genes, Regulator|*In Silico|*Transcription Factors|DIAPH1 protein, human|Formins 15 GRID2IP 15010865 Int. J. Mol. Med. 2004 4 0 0 15 Humans|Sequences, Nucleotide|Amino Acid Sequence|Sequence Alignment|Exons|Bioinformatics|Chromosome Mapping|Alternative Splicing|Introns|Isoforms|Sequence Homology, Amino Acid|cDNA|Expressed Sequence Tags|Carrier Proteins|Codon|*In Silico|DIAPH1 protein, human|Formins|FMNL2 protein, human 15 GRID2IP 14767582 Int. J. Mol. Med. 2004 4 1 0 15 Humans|Amino Acid Sequence|Sequence Alignment|Exons|Base Sequence|Bioinformatics|Alternative Splicing|Sequence Homology, Amino Acid|Introns|Chromosome Mapping|Expressed Sequence Tags|Isoforms|cDNA|Carrier Proteins|*In Silico|DIAPH3 protein, human|Formin Homology Proteins|DIAPH1 protein, human|FMNL2 protein, human 15 RUSC2 15375525 Oncol. Rep. 2004 2 0 0 57 Humans|Mice|Animals|FCHSD1 protein, human|Carrier Proteins|Amino Acid Sequence|Membrane Proteins|Exons|Base Sequence|Isoforms|Bioinformatics|Sequence Homology, Amino Acid|Protein Structure, Tertiary|Introns|Chromosome Mapping|Alternative Splicing|cDNA|Expressed Sequence Tags|*In Silico|SH3 Domain|Proteome 15 TCFL5 15585666 Nucleic Acids Res. 2004 PMC535687 10.1093/nar/gkh979 8 0 0 661 Humans|Male|Mice|Animals|calmegin|Meiosis|*Spermatogenesis|*Molecular Chaperones|*Calcium-Binding Proteins|Transcription Factors|Testis|Spermatids|Spermatocytes|Amino Acid Sequence|Helix-Loop-Helix Motifs|Northern Blot|Base Sequence|Basic Helix-Loop-Helix Transcription Factors|Promoter Regions, Genetic|DNA, Complementary|mRNA|Cloning, Molecular 15 TP53I11 15225615 FEBS Lett. 2004 10.1016/j.febslet.2004.05.057 5 5 0 22 Humans|*Arsenic Trioxide|TP53 protein, human|*Tumor Suppressor Protein p53|HEK293 Cells|Arsenicals|Apoptosis|Reactive Oxygen Species|Antineoplastic Agents|Oxides|Cell Line, Tumor|Cell Death|Transcriptional Activation|Up-Regulation 15 ADAP2 14690521 J. Neurochem. 2003 10.1046/j.1471-4159.2003.02143.x 5 3 1 62 Humans|*PtdIns|HEK293 Cells|*Adaptor Proteins, Signal Transducing|Inositol Phosphates|Binding Protein|Phosphatidylinositol Phosphates|Nerve Tissue Proteins|Receptors, Cytoplasmic and Nuclear|Recombinant Proteins|GTPase-Activating Proteins|Brain|Protein Binding|Amino Acid Sequence|Isoforms|Membrane Lipids|Cloning, Molecular|Ligands|Sequence Homology, Amino Acid 15 ERGIC2 12932305 DNA Cell Biol. 2003 10.1089/104454903322247343 1 0 0 139 Humans|Male|Mice|Animals|*PC3 Cell Line|Mice, Nude|pectenotoxin 1|*Prostate Cancer|Prostate|Transfections|Cell Line, Tumor|cDNA|Nuclear Protein|Cellular Senescence|Cell Division|Cell Proliferation|GLB1 protein, human|beta-Galactosidase 15 FIZ1 12566383 Hum. Mol. Genet. 2003 10.1093/hmg/ddg035 15 5 0 41 Humans|Mice|Animals|Cattle|*Transcription Factor|*Zinc Finger|cone rod homeobox protein|Homeodomain Proteins|Trans-Activators|*Retina|*Gene Expression Regulation|Promoter Regions, Genetic|Rhodopsin|Eye Proteins|Leucine Zipper|Transcription, Genetic|Retinitis Pigmentosa|FLT3 protein, human|*fms-Like Tyrosine Kinase 3|Basic-Leucine Zipper Transcription Factors|Transcriptional Activation|Repressor Proteins 15 GRID2IP 14612983 Int. J. Mol. Med. 2003 1 0 0 15 Rats|Humans|Mice|Animals|Base Sequence|GRID2IP protein, human|Carrier Proteins|Amino Acid Sequence|Chromosome Mapping|Exons|Sequence Alignment|Bioinformatics|Sequence Homology, Amino Acid|Introns|Expressed Sequence Tags|Codon|Alternative Splicing|DNA, Complementary|*In Silico|Genome, Human|Protein Binding|DIAPH1 protein, human 15 GRID2IP 12632087 Int. J. Oncol. 2003 2 0 0 15 Humans|Nucleotide Sequence|Amino Acid Sequence|Sequence Alignment|Exons|Bioinformatics|Proteins|Alternative Splicing|Sequence Homology, Amino Acid|Chromosome Mapping|cDNA|Expressed Sequence Tags|Introns|Carrier Proteins|*In Silico|Protein Binding|DIAPH1 protein, human|Formins|FMNL2 protein, human 15 PPP1R14C 12804574 Biochem. Biophys. Res. Commun. 2003 10.1016/s0006-291x(03)00976-8 14 40 1 90 *Phosphorylation|integrin-linked kinase|Myosin Phosphatase|phosphoprotein phosphatase inhibitor 1|nucleotide phosphotransferase|Protein Kinase A|Phosphoproteins|Protein Phosphatase 1|Muscle Proteins|Protein Kinase C|*Nucleotides|Signal Transduction|Muscle, Smooth, Vascular|Nucleotides, Cyclic 15 TCFL5 12923186 J. Biol. Chem. 2003 10.1074/jbc.M300053200 4 4 0 661 Humans|USF1 protein, human|*Upstream Stimulatory Factors|Promoter Regions, Genetic|*Transcription Factors, General|Transcription, Genetic|Helix-Loop-Helix Motifs|Transcriptional Activation|Gene Expression Regulation|Basic Helix-Loop-Helix Transcription Factors|E-Box Elements|Electrophoretic Mobility Shift Assay|Base Sequence|mRNA|Plasmids|Transfection|DNA 15 TP53I11 12883691 Oncol. Rep. 2003 5 2 0 22 Humans|*Arsenic Trioxide|*Tumor Suppressor Protein p53|*Stomach Neoplasms|*Apoptosis|Arsenicals|Leukemia, Promyelocytic, Acute|Antineoplastic Agents|Oxides|Cell Line, Tumor|Upregulation|Neoplasm Proteins|*Cell Death 15 ZNF219 14621294 DNA Res. 2003 10.1093/dnares/10.4.155 8 0 0 67 Humans|ZNF219 protein, human|SET protein, human|*Transcription Factors|Zinc Finger|Binding Sites|Nuclear Protein|Electrophoretic Mobility Shift Assay|Promoter Regions, Genetic|Base Sequence|Repressor Proteins|Transcription, Genetic|Amino Acid Sequence|cDNA|Kruppel-Like Transcription Factors|Sequence Alignment|Protein Binding|Consensus Sequence|Histone Chaperones 15 ADAP2 12018390 Eur. J. Cell Biol. 2002 10.1078/0171-9335-00242 5 3 2 62 Animals|Rats|*Binding Protein|Phosphatidylinositol Phosphates|Nerve Tissue Proteins|GTPase-Activating Proteins|Adaptor Proteins, Signal Transducing|Inositol Phosphates|Phosphatidylinositol|ADP-Ribosylation Factors|Protein Binding|Amino Acid Sequence|cDNA|Cell Membrane|Sequence Homology, Amino Acid|cnicin|*Sesquiterpenes|*Muscle, Skeletal 15 PFN3 11867228 Gene 2002 10.1016/s0378-1119(01)00855-1 13 2 1 11 Humans|Male|Animals|Rats|Mice|PFN1 protein, human|*Profilins|*Testis|Contractile Proteins|Actin Binding Proteins|Amino Acid Sequence|Base Sequence|Actin|Blotting, Northern|mRNA|Spermatogenesis|Sequence Homology, Amino Acid|In Situ Hybridization|*Genomics|DNA, Complementary|Cloning, Molecular|Exon|PFN2 protein, human 15 PPP1R14C 11812771 J. Biol. Chem. 2002 10.1074/jbc.M107558200 16 8 2 90 Humans|Animals|Mice|Rats|Swine|*Protein Phosphatase 1|*Morphine|Amino Acid Sequence|YWHAZ protein, human|*14-3-3 Proteins|Phosphorylation|YWHAE protein, human|Protein Kinase C|Myosin-Light-Chain Phosphatase|Signal Transduction|Phosphoproteins|Protein Kinase A|Muscle Proteins|OPRM1 protein, human|Receptors, Opioid, mu|cDNA|mRNA 15 ERGIC2 11445006 DNA Cell Biol. 2001 10.1089/10445490152122460 1 1 0 139 Male|Humans|*Nuclear Protein|Escherichia coli|pectenotoxin 1|*Prostate Cancer|*Cloning, Molecular|Prostate|*Downregulation|cDNA|Base Sequence|Neoplasm Proteins|Amino Acid Sequence|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Up-Regulation|RNA, Messenger|Sequence Homology, Amino Acid 15 PFN3 11549015 Appl. Microbiol. Biotechnol. 2001 10.1007/s002530100670 1 0 0 11 *beta Xylanase|*Saccharomyces cerevisiae|*Bacillus pumilus|*Yeast, Dried|Xylosidases|Cloning, Molecular|Xylans|Pheromone alpha Factor|Signal Sequence|Bacillus|Amino Acid Sequence|Alcohol Dehydrogenase II 15 PFN3 11423726 Exp. Nephrol. 2001 10.1159/000052621 6 1 0 11 Humans|Rats|Male|Mice|Animals|PFN1 protein, human|*Profilins|*Testis|*Cloning, Molecular|Contractile Proteins|Microfilament Proteins|cDNA|Amino Acid Sequence|Base Sequence|Actin|mRNA|Blotting, Northern|Poly A|Gene Expression|Sequence Homology, Amino Acid|PCR|Cytoskeleton|*Inferior Colliculi 15 SMR3B 10731710 J. Biochem. 2000 10.1093/oxfordjournals.jbchem.a022620 4 0 0 14 *Base Sequence|*Proline|Amino Acid Sequence|Proline-Rich Protein Domains|Salivary Proteins and Peptides|Exons|Introns|Sequence Homology, Nucleic Acid|Cloning, Molecular 15 ZBTB7C 11064366 J. Comp. Neurol. 2000 10.1002/1096-9861(20001211)428:2<266::aid-cne6>3.0.co;2-0 6 1 0 57 Rats|Animals|*Astrocytes|*Microglia|*Up-Regulation|*Injury, Spinal Cord|*Antibodies|Gliosis|Glial Fibrillary Acidic Protein|Spinal Cord|Neuroglia|Immunohistochemistry|Macrophages|Membrane Proteins|Tetraspanin 28|Cerebral Ventricles 15 ZNF219 10819330 DNA Res. 2000 10.1093/dnares/7.2.137 4 0 0 67 Humans|Male|Adult|*Zinc Finger|DNA-Binding Proteins|Transcription Factors|cDNA|Base Sequence|cDNA Library|Amino Acid Sequence|Intron|Chromosome Mapping|Green Fluorescent Proteins|Blotting, Northern|Cell Nucleus|*Human Chromosome|Cloning, Molecular|*Chromosome Structures|Exons|RNA, Messenger 15 DUSP11 10347225 J. Biol. Chem. 1999 10.1074/jbc.274.23.16590 19 0 0 83 Animals|Humans|RNA triphosphatase|*Acid Anhydride Hydrolases|*Protein Tyrosine Phosphatase|mRNA guanylyltransferase|Nucleotidyltransferases|Amino Acid Sequence|Virus, Nuclear Polyhedrosis|RNA|Sequence Homology, Amino Acid|Proteins|cDNA 15 FIZ1 10409713 J. Biol. Chem. 1999 10.1074/jbc.274.30.21478 5 3 0 41 Mice|Animals|*Tyrosine Kinase|FLT3 protein, human|*fms-Like Tyrosine Kinase 3|Proto-Oncogene Proteins|Signal Transduction|Phosphorylation|Phosphotyrosine|PHF20 protein, human|Amino Acid Sequence|SH2 Domain|*Biomarkers, Tumor|Protein Binding|Hematopoietic Stem Cells|Cell Lines|Zinc Fingers 15 DUSP11 9685386 J. Biol. Chem. 1998 10.1074/jbc.273.32.20347 14 3 0 83 *RNA|Tyrosine Phosphatases, Protein|Phosphatase, Dual-Specificity|Amino Acid Sequence|RNA Splicing|Base Sequence|Cloning, Molecular|Recombinant Proteins|RNA, Messenger|Cell Line|Substrate Specificity|Cell Nucleus|Sequence Homology, Amino Acid|Ribonucleoproteins 15 TCFL5 9763657 Cytogenet. Cell Genet. 1998 10.1159/000015061 3 0 0 661 Male|Humans|*Pachytene Stage|*Spermatocytes|In Situ Hybridization, Fluorescence|*Basic Helix-Loop-Helix Transcription Factors|Helix Loop Helix Motif|Transcription Factor|DNA Sequence|cDNA|Amino Acid Sequence|Cloning, Molecular|Chromosome Mapping|Testis|Spermatogenesis|Exons|Cell Nuclei|DNA|Gene Expression Regulation 15 ZBTB7C 9427755 EMBO J. 1998 PMC1170372 10.1093/emboj/17.1.215 16 2 2 57 Female|Humans|*Papillomaviridae|*Uterine Cervical Neoplasms|*Zinc Finger|*Oncogenes|*Carcinoma|ADIPOQ protein, human|*Adiponectin|Genes, Viral|Transcription, Genetic|Repressor Proteins|HeLa Cells|RNA, Messenger|Cell Cycle 15 PFN3 8771785 Plant J. 1996 10.1046/j.1365-313x.1996.10020269.x 28 1 1 11 *Profilins|*Arabidopsis|*Saccharomyces cerevisiae|*Pollen|Contractile Proteins|Arabidopsis Proteins|Amino Acid Sequence|Sequence Homology, Amino Acid|*Allergens|Microfilament Proteins|Actins|Hypocotyls|Base Sequence|Multigene Family|*Yeast, Dried|Schizosaccharomyces pombe|Plant Proteins|Cloning, Molecular 15 ZNF81 8938429 Genome Res. 1996 10.1101/gr.6.11.1056 4 0 0 22 Mice|Animals|Chromosome Mapping|Base Sequence|Artificial Chromosomes, Yeast|Cosmid|Genetic Linkage|*Chromosome Structures|X Chromosome|Genetic Markers|DNA|Expressed Sequence Tags|Pulsed-Field Gel Electrophoresis 15 ZNF81 8586441 Genomics 1995 10.1006/geno.1995.0031 4 0 0 22 *Zinc Finger|Transcription Factor|Base Sequence|Exons|Amino Acid Sequence|Transcription, Genetic|Cloning, Molecular|Chromosome Mapping|Open Reading Frames|Kruppel-Like Transcription Factors|DNA, Complementary|Sequence Homology, Amino Acid|*Chromosome Structures|Gene Expression Regulation|DNA 15 ZNF81 8530079 Genomics 1995 10.1006/geno.1995.1238 0 0 0 22 Humans|*Dinucleotide Repeats|Chromosome Mapping|*Microsatellite Markers|Genetic Markers|X Chromosome|Chromosomes, Artificial, Yeast|Genetic Linkage|*Dinucleoside Phosphates|*Chromosome Structures|Cosmid|Genes, Regulator|UBE1 protein, human|Ubiquitin-Activating Enzymes 15 ZNF81 8088827 Genomics 1994 10.1006/geno.1994.1274 3 0 0 22 *CpG Islands|*Chromosome Mapping|*Chromosomes, Artificial, Yeast|DNA-Binding Proteins|Transcription Factors|Genetic Linkage|Restriction Mapping|Repetitive Sequences, Nucleic Acid|Zinc Finger|X Chromosome|*Chromosome Structures|Genetic Markers|DNA Primers 15 ZNF81 8088799 Genomics 1994 10.1006/geno.1994.1255 2 0 0 22 Humans|*Yeast Artificial Chromosome|*Chromosomes, Human, X|*Chromosome Mapping|Base Sequence|Repetitive Sequences, Nucleic Acid|Genetic Markers|*Chromosome Structures|Gene Cluster|DNA Primers|Centromeres|Cosmids 15 ZNF81 8088786 Genomics 1994 10.1006/geno.1994.1240 3 0 0 22 Humans|*Base Sequence|*Chromosome Mapping|*Zinc Finger|X Chromosome|DNA-Binding Proteins|Repetitive Sequences, Nucleic Acid|Transcription Factors|Gene Cluster|*Chromosome Structures|Chromosomes, Artificial, Yeast|Genetic Markers|DNA|Pseudogene|Zinc|ELK1 protein, human|ets-Domain Protein Elk-1 15 ZNF81 8507979 Mamm. Genome 1993 10.1007/BF00417431 0 0 0 22 Humans|*Zinc|ZFY protein, human|*Kruppel-Like Transcription Factors|Zinc Finger|X Chromosome|Base Sequence|Chromosome Mapping|Amino Acid Sequence|Restriction Mapping|Cloning, Molecular|Multigene Family|Gene Expression|Nucleic Acid Hybridization|Gene Library|*Genes, X-Linked|Sequence Homology, Amino Acid 15 TUT1 3025059 Genetics 1986 PMC1203012 20 1 0 217 *Saccharomyces cerevisiae|*Alleles|*Plasmid|Thymidine Kinase|Simplexvirus|*Thymidine|DNA Replication|Cloning, Molecular|Genes, Viral|Mutation|Escherichia coli|Bromodeoxyuridine 15 ADGRA3 32537938 Insect Sci. 2020 10.1111/1744-7917.12841 0 0 0 13 Female|Animals|*Vitellogenesis|*Ovary|Juvenile Hormones|Oogenesis|Locusta migratoria|Vitellogenin|*G-Protein-Coupled Receptors|Oocytes|*Insects|Insect Proteins|RNAi 14 ALPK3 32480058 Am. Heart J. 2020 10.1016/j.ahj.2020.03.023 0 0 0 31 "Adult|Humans|Child|*Cardiomyopathy|*Heterozygote|*Phenotypes|Cardiomyopathy, Hypertrophic|Homozygote|Cardiomyopathy, Dilated|Muscle Proteins|Pedigree|Mutation|Protein Kinases" 14 AP5B1 32637184 Bone Res 2020 PMC7329904 10.1038/s41413-020-0101-8 0 0 0 411 14 B4GALNT3 32267274 Mol Omics 2020 10.1039/c9mo00175a 0 0 0 74 "Cricetinae|Humans|Animals|*Helicobacter pylori|*Mucin|N-acetylgalactosaminyl-1-4-N-acetylglucosamine|*Lactose|*Polysaccharides|TYRP1 protein, human|*Membrane Glycoproteins|MUC1 protein, human|*Mucin-1|CHO Cells|Cricetulus|Gastric Mucosa|Adhesins, Bacterial|N-Acetylgalactosaminyltransferases|Oligosaccharides|Recombinant Proteins" 14 B4GALNT3 32203219 Br. J. Cancer 2020 PMC7251111 10.1038/s41416-020-0772-3 0 0 0 74 "Humans|*Glycosyltransferases|*Pancreatic Cancer|Cell Movement|Cell Proliferation|Cell Line, Tumor|N-Acetylglucosaminyltransferases|Biomarkers, Tumor|Disease Progression" 14 B4GALNT3 32150548 PLoS Genet. 2020 PMC7108731 10.1371/journal.pgen.1008605 0 0 0 74 "Cholesterol, LDL|Cholesterol, HDL|Triglycerides|Cholesterol|Genome-Wide Association Study|Cardiovascular Disease|Lipoproteins|Phenotype|Genetic Variation|Polymorphism, Single Nucleotide|Risk Factors|Biomarkers" 14 CEP104 32453716 J. Clin. Invest. 2020 10.1172/JCI131656 0 0 0 196 "Animals|Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Ciliopathy|Cilia|Zebrafish|Membrane Proteins|Phenotype|Mutation|CSPP1 protein, human|Microtubule-Associated Proteins|Cell Cycle Proteins|CCDC66 protein, human|Eye Proteins|ARMC9 protein, human" 14 CEP104 32173538 Gene 2020 10.1016/j.gene.2020.144561 0 0 0 196 "Aged|Humans|Mice|Animals|Genome-Wide Association Study|Quality of Life|*Presbycusis|Hair Cells, Auditory|Cochlea|Aging|Mutation|Acoustic Stimulation|*Longitudinal Studies|Italy|DCLK1 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|PCDH20 protein, human|Nerve Tissue Proteins|Cadherins" 14 ELMOD2 32614697 Mol. Biol. Cell 2020 10.1091/mbc.E20-01-0012 0 0 0 68 *Cytokinesis|GTP-Binding Proteins|Cytoskeletal Proteins|Microtubules|ADP-Ribosylation Factors|Mitochondria 14 GPR146 32354568 Bioorg. Med. Chem. Lett. 2020 10.1016/j.bmcl.2020.127208 0 0 0 25 "Humans|Cricetinae|Mice|Animals|*C-Peptide|Receptors, G-Protein-Coupled|beta-Arrestins|Arrestins|Signal Transduction|Diabetes Mellitus|Protein Binding|Fluorescence Microscopy|CHO Cells|Cytoplasm" 14 katnal2 31991798 Cells 2020 PMC7072489 10.3390/cells9020292 0 0 0 15 "Humans|*Dimerization|Katanin|Microtubules|Amino Acid Sequence|Protein Domains|Adenosine Triphosphatases|AAA Domain|Sequence Homology, Amino Acid" 14 PATL2 32048119 J. Assist. Reprod. Genet. 2020 PMC7183019 10.1007/s10815-020-01698-6 1 0 0 18 "Humans|Female|*Infertility, Female|*Homozygote|Oocytes|Pedigree|Mutation|intraovarian peptides|*Intercellular Signaling Peptides and Proteins" 14 pdxdc1 32644145 Neuro-oncology 2020 10.1093/neuonc/noaa161 0 0 0 62 "Humans|Male|*Pedigree|Genetic Linkage|Genetic Predisposition to Disease|Genotype|Genome, Human|Prostatic Neoplasms|*Brain Neoplasms|*Brain" 14 pdxdc1 32550916 Theranostics 2020 PMC7295062 10.7150/thno.42110 0 0 0 62 "*Kidney Transplantation|Graft Rejection|Transplantation, Homologous|Kidney|ROC Curve|Biomarkers" 14 PLEK2 32566639 Int J Genomics 2020 PMC7285394 10.1155/2020/1097602 0 0 0 18 "Humans|Male|*Likelihood Functions|*Survival Analysis|Prognosis|*Prostate Cancer|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Biomarkers, Tumor" 14 STK32B 32403311 Int J Mol Sci 2020 PMC7246997 10.3390/ijms21093384 0 0 0 8 "Infant, Newborn|Humans|Pregnancy|Female|Abruption, Placental|*Pregnancy Complications|Genome-Wide Association Study|Pre-Eclampsia|Preterm Birth|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Reproductive History|Phenotype" 14 TTC28 32617189 PeerJ 2020 PMC7323713 10.7717/peerj.9294 0 0 0 73 "Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Carcinoma, Squamous Cell|Mutations|*Databases, Genetic|DNA Copy Number Variations|Genome, Human|Genetic Predisposition to Disease|Asian|Genomics|Whole Genome Sequencing|Japan" 14 TTC28 32340176 Cancers (Basel) 2020 PMC7226611 10.3390/cancers12041039 0 0 0 73 "Uveal melanoma|*Uveal Neoplasms|*Melanoma|*Sequencing, Next-Generation|Eukaryotic Initiation Factor-1|Ubiquitin Thiolesterase|GTP-Binding Protein alpha Subunits|DNA Mutational Analysis|RNA Splicing Factors|Mutations|GTP-Binding Protein alpha Subunits, Gq-G11|Tumor Suppressor Proteins|Phosphoproteins|DNA Copy Number Variations" 14 WDPCP 32055034 Genet. Med. 2020 10.1038/s41436-020-0761-1 0 0 0 51 *Ciliopathies|Bardet-Biedl Syndrome|Cilia|Phenotypes|Retina 14 ZNHIT3 32048886 Autophagy 2020 10.1080/15548627.2020.1725377 2 0 0 68 Humans|*Autophagy|Mitophagy|Mitochondria|Reactive Oxygen Species|*Quality Control 14 AAGAB 31788832 Ann. Neurol. 2019 10.1002/ana.25658 0 0 0 66 *Restless Legs Syndrome|*DNA Mutational Analysis|Pedigree|Lod Score|Chromosome Mapping|Genetic Predisposition to Disease|Genotype|Genetic Loci|Phenotype|Nerve Tissue Proteins 14 AAGAB 31526046 J Cutan Med Surg 2019 10.1177/1203475419878161 0 0 0 66 "Keratosis palmoplantaris papulosa|Keratoderma, Palmoplantar|Pedigree|Adaptor Proteins, Vesicular Transport|Mutation|Carrier Proteins" 14 AAGAB 31353312 Dev. Cell 2019 PMC6702059 10.1016/j.devcel.2019.06.013 3 2 0 66 "Humans|*Endocytosis|Clathrin|Adaptor Protein Complex 2|Coated Pits, Cell-Membrane|Clathrin-Coated Vesicles|Adaptor Protein Complex alpha Subunits|Adaptor Proteins, Vesicular Transport|Protein Binding|Protein Transport|Amino Acid Sequence|Binding Protein|AAGAB protein, human" 14 AAGAB 31200764 Breast Cancer Res. 2019 PMC6570893 10.1186/s13058-019-1159-3 2 0 0 66 "*Neoadjuvant Therapy|Prognosis|Receptor, ErbB-2|Receptors, Estrogen|Antineoplastic Combined Chemotherapy Protocols|Biomarkers, Tumor|Taxoids|Gene Expression Profiling|Neoplasm Staging" 14 ADGRA3 31659746 Ann. N. Y. Acad. Sci. 2019 PMC6899654 10.1111/nyas.14263 1 0 0 13 "*Arrestin|*Endocytosis|Receptors, G-Protein-Coupled|beta-Arrestins|Clathrin|Arrestins|Signal Transduction|Protein Binding|Cell Membrane|prosecretin|Secretin|G Proteins|Ligands|Phosphorylation" 14 ALPK3 31580838 Neuropharmacology 2019 10.1016/j.neuropharm.2019.107803 0 0 0 31 "Humans|Infant|Animals|Rats|Infant, Newborn|*Neuroprotective Agents|*Leptin|Preterm Infants|*Ischemia-Hypoxia, Brain|*Hippocampus|Chromatography, Liquid|Tandem Mass Spectrometry|Animals, Newborn|Brain Injuries|Brain|Peptides|Disease Models, Animal|Hypoxia" 14 ALPK3 31554410 Circulation 2019 PMC6791514 10.1161/CIRCULATIONAHA.119.041161 6 0 0 31 "*Heart Ventricles|*Heart Failure|Stroke Volume|Ventricular Function, Left|Magnetic Resonance Imaging, Cine|Ventricular Remodeling|Ventricular Dysfunction, Left|Atherosclerosis|*Phenotypes|Prospective Studies|Risk Factors|Morphogenesis" 14 ALPK3 31074094 Am. J. Med. Genet. 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Neurol. 2019 PMC7263419 10.1002/ana.25426 6 1 0 65 Humans|*Charcot-Marie-Tooth Disease|*Phenotype|Myelin Proteins|Modifier Gene|Neural Conduction|Tooth Diseases 14 SLC7A4 30614210 Mol Genet Genomic Med 2019 PMC6393688 10.1002/mgg3.507 4 0 0 13 "Humans|Chromosome 22q11.2 Microduplication Syndrome|*Autism Spectrum Disorder|*Penetrance|Chromosome Duplication|DiGeorge Syndrome|Abnormalities, Multiple|*Phenotypes|Low-Copy Repeats|Chromosomes, Human, Pair 22" 14 TESPA1 31848144 Ann. Rheum. Dis. 2019 10.1136/annrheumdis-2019-215533 0 0 0 97 "*Autoimmunity|*T-Lymphocytes|*Lupus Erythematosus, Systemic|*Rheumatoid Arthritis|*Autoimmune Diseases|Sjogren's Syndrome|Genetic Predisposition|Genotype|Polymorphism, Single Nucleotide|*Germ Line" 14 TESPA1 31699214 Adv. 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Lipid Res. 2018 PMC5880495 10.1194/jlr.P080333 3 0 0 65 "Humans|*Fenofibrate|*Exome|*Hypolipidemic Agents|*Lipids|*Meal|Triglycerides|*European Continental Ancestry Group|Dietary Fats|Cholesterol, HDL|Postprandial Period|*Diet|Cholesterol, LDL|*Cohort Studies|Genome-Wide Association Study" 14 STK32B 29899728 Front Neurol 2018 PMC5989317 10.3389/fneur.2018.00387 0 2 0 8 "Humans|*Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Genetic Association Studies|Genotype|Parkinson Disease|Protein-Serine-Threonine Kinases" 14 STK32B 29604450 J Psychiatr Res 2018 10.1016/j.jpsychires.2018.03.008 2 0 0 8 "Humans|Adult|Adolescent|*Promoter Regions, Genetic|CpG Islands|DNA Methylation|Epigenesis, Genetic|*Anxiety Disorders|Single Nucleotide Polymorphisms|*Protein-Serine-Threonine Kinases|Cohort Studies|RNA, Messenger" 14 TESPA1 29867947 Front Immunol 2018 PMC5960706 10.3389/fimmu.2018.00965 1 26 0 97 "Mice|Animals|Lymphocyte Activation|T-Lymphocytes|B-Lymphocytes|CD40 Antigens|Signal Transduction|Adaptor Proteins, Signal Transducing|Mice, Inbred C57BL" 14 TESPA1 29528040 Nat Commun 2018 PMC5857672 10.1038/ncomms16183 0 1 0 97 "*Calcium|*Inositol 1,4,5-Trisphosphate Receptors|*T Cell Receptor|Inositol 1,4,5-Trisphosphate|*Calcium, Dietary|Signal Transduction" 14 TMUB1 29967478 Sci Rep 2018 PMC6028644 10.1038/s41598-018-28339-4 1 24 0 225 "Rats|Animals|cyclophilin B|*Cyclophilins|CAMLG protein, human|Adaptor Proteins, Signal Transducing|*Cell Proliferation|Carrier Proteins|Nuclear Proteins|Hepatocytes|Signal Transduction|Protein Binding|Co-Immunoprecipitation|Cell Line" 14 TMUB1 29777440 Dig. Dis. Sci. 2018 10.1007/s10620-018-5113-5 1 2 0 225 *Liver Regeneration|Hepatocytes|Cell Proliferation|MicroRNAs|Liver|Hepatectomy|Carrier Proteins|Signal Transduction|Cell Line|*Focal Nodular Hyperplasia 14 TMUB1 29344642 Mol Med Rep 2018 PMC5802207 10.3892/mmr.2018.8451 3 27 0 225 Rats|Animals|*Protein A|*Hepatocytes|Liver Regeneration|*M Phase|Cell Proliferation|Nuclear Proteins|Carrier Proteins|Liver|*Cell Cycle|Hepatectomy|Cyclin A2|Cyclin B1|Signal Transduction|mRNA|Cell Line|*Microarray Analysis 14 TTC28 29738714 Dev. Cell 2018 PMC5983389 10.1016/j.devcel.2018.04.009 1 6 0 73 "Animals|AURKB protein, human|*Aurora Kinase B|Zebrafish|Microtubules|Zebrafish Proteins|Spindle Apparatus|*Cadherins|Embryo, Nonmammalian|*Cleavage Stage, Ovum|Mitosis|Morphogenesis|DCHS1b protein, zebrafish" 14 WDPCP 29588463 Sci Rep 2018 PMC5869593 10.1038/s41598-018-23520-1 3 0 0 51 "Humans|*Syndromes|*Ciliopathies|*DNA Copy Number Variations|*Retinal Diseases|Sequencing, Next-Generation|Phenotypes|Bardet-Biedl Syndrome 12|Bardet-Biedl Syndrome|Mutation|Pedigree|Genotype|Retina|Cohort Studies|VPS13B protein, human|Vesicular Transport Proteins|ALMS1 protein, human|Proteins" 14 WDPCP 29487191 Sci Signal 2018 10.1126/scisignal.aah5770 0 1 0 51 "Mice|Animals|*Coronary Vessels|*Epithelial-Mesenchymal Transition|Endothelial Cells|*Epicardium|*Cell Migration|Smooth Muscle Cells|Organogenesis|Muscle, Smooth, Vascular|Cell Differentiation|T-Box Domain Proteins|Signal Transduction|Gene Expression Regulation, Developmental" 14 WDPCP 29434467 Cancer Inform 2018 PMC5802704 10.1177/1176935118755341 0 2 0 51 "Humans|Female|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Processes, Epigenetic|*Genomics|DNA Methylation|Gene Expression Regulation, Neoplastic|DNA Copy Number Variations|DNA Mutational Analysis" 14 ZNF407 29523860 Sci Rep 2018 PMC5844893 10.1038/s41598-018-22753-4 1 2 0 21 "Humans|*Alleles|Autism Spectrum Disorder|*Autistic Disorder|KMT2C protein, human|DNA-Binding Proteins|Transcription Factors|miRNAs|Genetic Predisposition to Disease|Brain" 14 ZNF407 29330500 Sci Rep 2018 PMC5766549 10.1038/s41598-017-18916-4 5 12 0 21 Cattle|Animals|Female|*Milk Proteins|*Genome-Wide Association Study|Milk|Casein|Breeding|Quantitative Trait Loci|Cheese|Single Nucleotide Polymorphism|Genotype|Protein Biosynthesis 14 ZNHIT3 29700228 Science 2018 PMC6020066 10.1126/science.aar2663 51 7 0 68 "Humans|ribosome receptor|Proteomics|*Ribophagy|MTOR protein, human|TOR Serine-Threonine Kinases|*Receptors, Cytoplasmic and Nuclear|Lysosomes|Autophagosomes|*Starvation|Mechanistic Target of Rapamycin Complex 1|MAP1LC3B protein, human|Microtubule-Associated Proteins|Signal Transduction|FMR1 protein, human|Fragile X Mental Retardation Protein|Ribosomes|Cell Nucleus|NUFIP1 protein, human" 14 AAGAB 28239884 Clin. 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Genet. 2017 10.1111/age.12532 3 0 0 13 "Animals|Humans|*Chickens|*Chromosomes, Human, Pair 4|Crosses, Genetic|Quantitative Trait Loci|Chromosome Mapping|Genotype|Phenotype|Body Weight|Body Composition" 14 ALPK3 28630369 Cold Spring Harb Mol Case Stud 2017 PMC5593152 10.1101/mcs.a001859 2 0 0 31 "Humans|Male|Infant|Cardiomyopathy, Hypertrophic|Homozygote|Genetic Testing|Cardiomyopathy, Dilated|Pedigree|Primary Cardiomyopathy|Mutation, Frame Shift|Mutation|Sequencing, Whole Exome|Genetic Predisposition to Disease|Muscle Proteins|Phenotype|Sequencing, Next-Generation|Echocardiography|Heart" 14 ALPK3 28296976 PLoS ONE 2017 PMC5351854 10.1371/journal.pone.0172995 17 16 0 31 "*Exome|*Cardiomyopathy, Dilated|Mutation, Missense|Pedigree|Heterozygote|Adaptor Proteins, Signal Transducing|Apoptosis Regulatory Proteins" 14 ALPK3 28223422 Circ. Res. 2017 PMC5380229 10.1161/CIRCRESAHA.116.310559 10 1 0 31 "*Cardiomyopathy, Hypertrophic|Mutations|Pedigree|Genetic Testing|Connectin|Phenotype|Sarcomere|Myosin Light Chains|Muscle Proteins" 14 AP5B1 29180427 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5740629 10.1073/pnas.1717327114 31 0 0 411 14 B4GALNT3 28853212 Mol Oncol 2017 PMC5663998 10.1002/1878-0261.12134 5 10 0 74 14 BEX4 28295929 J. Biochem. Mol. 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Cancer 2017 PMC5445297 10.1186/s12943-017-0661-4 17 90 0 108 "*Reactive Oxygen Species|*Autophagy|Neuroblastoma|Forkhead Box Protein O3|Mitochondria|Apoptosis|Peroxisomes|Forkhead Transcription Factors|Cell Line, Tumor|Cell Death|Proteins|Phosphorylation" 14 ELMOD2 28380071 PLoS ONE 2017 PMC5381910 10.1371/journal.pone.0175164 6 19 0 68 Mice|Animals|*GTPase|*Mitochondria|Mitochondrial Fusion|Mitochondrial Proteins|Cytoskeletal Proteins|Membrane Proteins|Adenosine Triphosphate|Energy Metabolism 14 ELMOD2 28324667 Cell Cycle 2017 PMC5444355 10.1080/15384101.2017.1304329 2 2 0 68 "Humans|Female|Mice|Animals|*GTPase Activating Protein|*Oocytes|Meiosis|Chromosome Segregation|Polar Bodies|Mitochondrial Dynamics|Anaphase|Cell Cycle Proteins|GTPase|Cytoskeletal Proteins|Aneuploid|ARL2 protein, human|GTP-Binding Proteins|ELMOD2 protein, human" 14 GPR146 28993767 Front Immunol 2017 PMC5622154 10.3389/fimmu.2017.01146 2 41 0 25 "Adult|Infant|Infant, Newborn|Humans|Cytomegalovirus|Cytomegalovirus Infections|*Genomics|Herpesviridae Infections|Antiviral Agents|siRNA|Dendritic Cells" 14 GPR146 28464285 Immunology 2017 PMC5543731 10.1111/imm.12752 2 5 0 25 "Chlorocebus aethiops|Mice|Animals|*IFN-Regulatory Factor 3|*Transductions, Signal|*Antiviral Agents|Herpesvirus 1, Human|Herpes Simplex|Interferon-beta|Interferon Type I|Virus Replication|Vesiculovirus|Vesicular stomatitis Indiana virus|Host-Pathogen Interactions|Protein-Serine-Threonine Kinases|Immunity, Innate|Viral Proteins|Virus Infections|Vero Cells|Mice, Knockout|Hes1 protein, mouse" 14 katnal2 29136647 PLoS Genet. 2017 PMC5705150 10.1371/journal.pgen.1007078 9 4 0 15 "Humans|Male|Animals|Mice|*Katanin|*Haploidy|*Germ Cells|Spermatogenesis|Sperm|Tubulin|Microtubules|Infertility, Male|Seminiferous Epithelium|Basal Body|Adenosine Triphosphatases|Amino Acid Sequence|*Reproduction|KATNAL1 protein, human|KATNAL2 protein, mouse" 14 LCN8 28795405 Acta Psychiatr Scand 2017 10.1111/acps.12778 14 0 0 2 "Humans|*Veterans|*Stress Disorders, Post-Traumatic|*DNA Methylation|Combat Disorders|Vietnam Conflict|Epigenesis, Genetic" 14 PATL2 28965849 Am. 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Genet. 2017 PMC5630161 10.1016/j.ajhg.2017.08.009 6 0 0 18 "Humans|Female|*Infertility, Female|*Oocyte|*Mutations|Meiosis|Phenotype|Sequencing, Whole Exome|Homozygote" 14 pdxdc1 29277971 Mol Nutr Food Res 2017 PMC6120138 10.1002/mnfr.201700661 2 11 0 62 "Animals|Rats|*Fish Oil|*Glycosylation|MUC2 protein, human|*Mucin-2|*Colon|Dietary Fats|Corn Oil|Intestinal Mucosa|Microbiota, Gut|Colonic Neoplasms" 14 pdxdc1 28485732 Transl Psychiatry 2017 PMC5534953 10.1038/tp.2017.85 2 2 0 62 "Animals|Mice|*Prepulse Inhibition|DRD2 protein, human|Dopamine D2 Receptor|Reflex, Startle|Sensory Gating|Antipsychotic Agents|Schizophrenia|Corpus Striatum|*Acoustic" 14 pdxdc1 28339748 Neuro-oncology 2017 PMC5737684 10.1093/neuonc/now288 3 0 0 62 "Genome-Wide Association Study|*Glioma|*Genotype|Genetic Predisposition to Disease|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Brain Neoplasms" 14 PLEK2 29202466 J. Clin. Invest. 2017 PMC5749534 10.1172/JCI94518 2 0 0 18 "Humans|Mice|Animals|platelet protein P47|*Myeloproliferative Disorders|JAK2 protein, human|Janus Kinase 2|Phosphoproteins|STAT5A protein, human|STAT5 Transcription Factor|Amino Acid Substitution|Mutation, Missense|Hematologic Neoplasms|Tumor Suppressor Proteins" 14 PRH2 29191562 EBioMedicine 2017 PMC5832611 10.1016/j.ebiom.2017.11.019 3 8 0 19 "Humans|Child|*Proline|*Dental Caries|Streptococcus mutans|Saliva|Polymorphism, Genetic|*Acids|Phenotypes|*Lifestyle|Sweden|PRH1 protein, human|Salivary Proline-Rich Proteins|PRH2 protein, human" 14 SIPA1L2 28380328 Neurosci. 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Oncol. 2017 10.1016/j.ygyno.2017.09.032 1 0 0 73 "Humans|Female|*Endometriosis|*Retroelements|*B-DNA|*Ovarian Cancers|Adenocarcinoma, Clear Cell|*Long Interspersed Nucleotide Elements|Carcinoma, Endometrioid|Nuclear Proteins|Class I Phosphatidylinositol 3-Kinases|Transcription Factors|Endometrium|Mutation" 14 TTC28 28548104 Nat Commun 2017 PMC5477513 10.1038/ncomms15290 30 17 0 73 "Humans|Phosphatidylinositol 3-Kinases|*Esophageal Squamous Cell Carcinoma|Squamous Cell Carcinomas|*Mutation|*Genomics|Esophageal Neoplasms|DNA Copy Number Variations|Exome|Genome, Human|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Esophagus|Polymorphism, Single Nucleotide|*Alcohol Drinking|Databases, Genetic|Cell Cycle|China" 14 WDPCP 28289185 J. Med. 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Cardiol. 2016 10.1016/j.jacc.2015.10.093 14 1 0 31 "Adult|Child|Humans|*Cardiomyopathy|Cardiomyopathy, Dilated|Homozygote|Muscle Proteins|Myocytes, Cardiac|Pedigree|Mutation|Protein Kinases" 14 AP5B1 27392064 PLoS ONE 2016 PMC4938559 10.1371/journal.pone.0158941 0 7 1 411 14 BEX4 27512957 Cell Death Dis 2016 PMC5108325 10.1038/cddis.2016.240 5 34 1 64 Humans|*Sirtuin 2|*Microtubules|Tubulin|*Oncogenes|Microtubule-Associated Proteins|Acetylation|*Oncogenesis|HeLa Cells|Apoptosis 14 BEX4 27297407 J. Exp. Clin. Cancer Res. 2016 PMC4906687 10.1186/s13046-016-0355-6 3 22 1 64 14 C8orf37 27008867 Hum. Mol. 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Cell Proteomics 2016 PMC4858946 10.1074/mcp.M115.056465 12 24 1 15 Animals|*Katanin|*Proteomics|Microtubule|Spindle Apparatus|Interphase|Adenosine Triphosphatases|Mitosis|Amino Acid Sequence|*Mammals 14 PATL2 27335345 Plant Cell Physiol. 2016 PMC4970614 10.1093/pcp/pcw098 5 20 1 18 "*Arabidopsis|*Cytokinesis|*Binding Protein|*Mitogen-Activated Protein Kinases|Arabidopsis Proteins|Plant Immunity|Gene Expression Regulation, Plant|MAP Kinase Signaling System|Phosphorylation|MAP Kinase Kinase 6|*Phosphoinositides|Signal Transduction" 14 PLEK2 27581786 Gene 2016 10.1016/j.gene.2016.08.043 8 6 0 18 "*Nonsmall Cell Lung Cancer|*Epithelial-Mesenchymal Transition|Lung Neoplasms|CXCR4 protein, human|*Receptors, CXCR4|*Signal Transduction|Cell Line, Tumor|Transforming Growth Factor beta1|Gene Expression Regulation, Neoplastic|Cell Movement|*B Cells" 14 SIPA1L2 28011712 Hum. Mol. 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Aging 2016 10.1016/j.neurobiolaging.2015.12.016 4 5 0 65 "Humans|*Parkinson Disease|Genome-Wide Association Study|Taiwan|Single Nucleotide Polymorphisms|Gene Frequency|Genetic Predisposition to Disease|Asian|Genetic Loci|GTP Cyclohydrolase|Genotype|Allele|Ethnic Groups|Case-Control Studies|VPS13C protein, human|Proteins" 14 STK32B 27797806 Brain 2016 PMC5382938 10.1093/brain/aww242 13 2 0 8 Humans|*Genome-Wide Association Study|*Essential Tremor|Single Nucleotide Polymorphisms|Genotype|Glutamate Plasma Membrane Transport Proteins|Gene Frequency|Genetic Predisposition to Disease|Allele|Case-Control Studies|Serine Threonine Kinase|Tremor 14 TTC28 27745836 Am. J. Hum. 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Genet. 2016 PMC4978421 10.1038/ng.3558 27 23 1 51 "Humans|Animals|Mice|*Basal Bodies|*Ciliopathy|Cilia|*Protein Transport|Flagella|Microtubule-Associated Proteins|Signal Transduction|Multiprotein Complexes|Microtubule|Cell Polarity|Cell Movement|Phenotypes|inturned protein, mouse|Membrane Proteins" 14 ZNF407 27624101 Am. J. Physiol. Endocrinol. Metab. 2016 PMC5130358 10.1152/ajpendo.00234.2016 4 7 0 21 "Mice|Animals|Insulin|*Gene Expression|PPAR alpha|*Upregulation|PPAR delta|*Homeostasis|PPAR gamma|Glucose|Insulin Resistance|Adipogenesis|Lipid Metabolism|Transgenic Mouse|mRNA|Muscle, Skeletal|Zinc Fingers" 14 ZNHIT3 27594683 Structure 2016 10.1016/j.str.2016.07.016 7 0 0 68 "Humans|*Ribonucleoproteins, Small Nucleolar|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Ribonucleoproteins, Small Nuclear|Small Nucleolar RNA|Ribosomal Proteins|Nuclear Proteins|Cell Nucleolus|Protein Binding|NUFIP1 protein, human|RNA-Binding Proteins" 14 AAGAB 26608363 Acta Derm. Venereol. 2015 10.2340/00015555-2304 1 0 0 66 "Humans|Keratosis palmoplantaris papulosa|*Keratoderma, Palmoplantar|Skin|Pedigree|Mutation|Phenotypes|Genetic Predisposition to Disease|Adaptor Proteins, Vesicular Transport|Binding Protein|Genotypes|*Phenotypic Variability|AAGAB protein, human" 14 AAGAB 25919143 J. Dermatol. 2015 10.1111/1346-8138.12916 0 1 0 66 "Female|Humans|*Etretinate|Keratosis palmoplantaris papulosa|*Keratoderma, Palmoplantar|Skin|Mutations|Pedigree|Genetic Predisposition to Disease|Adaptor Proteins, Vesicular Transport|AAGAB protein, human" 14 ADGRA3 25898550 Zhonghua Nan Ke Xue 2015 2 0 0 13 "Male|Humans|Spermatogonia|*Adult Germline Stem Cells|Testis|Sertoli Cells|Cell Separation|Stem Cells|Cells, Cultured|Flow Cytometry|Cell Differentiation|Cell Proliferation" 14 ADGRA3 25713288 Pharmacol. Rev. 2015 PMC4394687 10.1124/pr.114.009647 108 0 9 13 "*Pharmacology, Clinical|ADGRE5 protein, human|ADGRG1 protein, human|*G-Protein-Coupled Receptors|Signal Transduction|Cell Membrane|CELSR2 protein, human|Cadherins|CELSR1 cadherin, human|Antigens, CD" 14 AP5B1 26542096 Nat Commun 2015 PMC4667629 10.1038/ncomms9804 35 0 3 411 14 AP5B1 26085577 Hum. Mol. Genet. 2015 PMC4527494 10.1093/hmg/ddv220 24 4 1 411 14 AP5B1 25854761 Nat Commun 2015 PMC4403312 10.1038/ncomms7793 30 1 2 411 14 B4GALNT3 25803323 Oncotarget 2015 PMC4484453 10.18632/oncotarget.3593 23 2 2 74 "Humans|*Thyroid Cancer, Papillary|Thyroid Neoplasms|Carcinoma, Papillary|*Gene Fusion|Proto-Oncogene Proteins B-raf|Proto-Oncogene Proteins c-ret|Mutation|Carcinoma|DNA Mutational Analysis|Gene Rearrangement|Genetic Heterogeneity|Biomarkers, Tumor|Phenotype|Genetic Predisposition to Disease|DICER1 protein, human|Ribonuclease III|DEAD-box RNA Helicases|WNK1 protein, human" 14 BEX4 26408910 Biochim. Biophys. Acta 2015 10.1016/j.bbcan.2015.09.001 7 2 0 64 14 C8orf37 26690675 BMC Med Genomics 2015 PMC4685628 10.1186/s12920-015-0160-7 5 0 1 58 "Humans|Adolescent|*Thyroid Cancer, Papillary|*Genome-Wide Association Study|Thyroid cancer, medullary|Thyroid Carcinomas|Carcinoma, Medullary|Carcinoma, Neuroendocrine|Carcinoma, Papillary|Proto-Oncogene Proteins c-ret|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide" 14 C8orf37 25802487 Mol. Vis. 2015 PMC4357040 7 0 0 58 "Pakistan|*Retinitis Pigmentosa|Genes, Recessive|Pedigree|DNA Mutational Analysis|Homozygote|Eye Proteins|Base Sequence|Genetic Linkage|Introns|Mutation|Electroretinography" 14 CASC1 25662842 J. Plant Physiol. 2015 10.1016/j.jplph.2014.12.013 1 2 0 21 "*Botrytis|jasmonic acid|Oxylipins|Cyclopentanes|ethylene|Ethylenes|Disease Resistance|Plant Diseases|Lycopersicon esculentum|Gene Expression Regulation, Plant|Salicylic Acid|Plant Growth Regulators|Plant Proteins|Plant Leaves|*Piper nigrum|Signal Transduction" 14 CEP104 26477546 Am. J. Hum. Genet. 2015 PMC4667103 10.1016/j.ajhg.2015.09.009 18 5 2 196 "Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Canada|Cerebellar Diseases|Ciliopathy|*Mutations|Cilia|Basal Bodies|Homozygote|Exome|Pedigree|Whole Exome Sequencing" 14 DEPP1 25963801 Rheumatol. Int. 2015 10.1007/s00296-015-3276-3 1 0 0 108 "Humans|*Dupuytren Contracture|*Computational Biology|*Fibroblasts|Gene Regulatory Networks|Gene Expression Profiling|Protein Interaction Maps|Fascia|Signal Transduction|Downregulation|SLCO2A1 protein, human|Organic Anion Transporters|C10orf10 protein, human" 14 ELMOD2 26235595 Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2015 10.1016/j.cbpc.2015.07.009 1 1 0 68 "Animals|*Tetrachlorodibenzo-p-dioxin|*Bass|titanium dioxide|*Titanium|*Liver|*Gene Expression|*Biotransformation|ATP-Binding Cassette Transporters|Water Pollutants, Chemical|Nanoparticles|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B|Cytochrome P450" 14 ELMOD2 25904333 Mol. Biol. Cell 2015 PMC4462949 10.1091/mbc.E14-11-1504 15 33 0 68 "Humans|*Lipid Droplets|*Triglyceride Lipase|*Lipoylation|Coat Protein Complex I|ADP-Ribosylation Factor 1|*Adipocyte|Endoplasmic Reticulum|Triglycerides|Lipid Metabolism|RNA, Small Interfering|RNA Interference|Lipids|Biological Transport|Protein Transport|Hydrolysis|HeLa Cells|Guanine Nucleotide Exchange Factors|ELMOD2 protein, human" 14 GPR146 26495706 Tsitologiia 2015 0 0 0 25 "Humans|*C-Peptide|Insulin|Signal Transduction|Proinsulin|G-Protein-Coupled Receptors|Diabetes Mellitus, Type 1|Diabetic Nephropathy|Mitogen-Activated Protein Kinases" 14 katnal2 26506440 Eur J Med Genet 2015 10.1016/j.ejmg.2015.10.007 8 0 0 15 "Child|Humans|Bohring syndrome|*Intellectual Disability|*Penetrance|*Mutations|Craniosynostoses|*Haploinsufficiency|Developmental Disabilities|Exome|Heterozygote|Phenotype|Transcription Factors|Loss of Function Mutation|ASXL3 protein, human" 14 katnal2 26153462 Cell. Mol. Life Sci. 2015 10.1007/s00018-015-1980-5 13 1 1 15 "Animals|Mice|*Katanin|*Binding Proteins|Phylogeny|Mitotic Spindle|Centrioles|Microtubules|*Protein Isoforms|Cilia|Mitosis|Cytokinesis|Adenosine Triphosphatases|Meiosis|*Nucleotides|NUBP2 protein, mouse|GTP-Binding Proteins|Nubp1 protein, mouse|KATNAL2 protein, mouse" 14 PATL2 26031216 J. Neurosci. Res. 2015 10.1002/jnr.23605 4 1 0 18 "Animals|Mice|*Methamphetamine|*Nucleus Accumbens|*MicroRNAs|Amphetamine-Related Disorders|Central Nervous System Stimulants|Messenger RNA|Gene Expression|Mice, Inbred C57BL" 14 pdxdc1 26584805 Genes Nutr 2015 PMC4653118 10.1007/s12263-015-0502-2 18 0 1 62 "Humans|*Fatty Acids, N-6|*Genome-Wide Association Study|*Chinese|Fatty Acid Desaturases|Polyunsaturated Fatty Acids|Genetic Loci|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Arachidonic Acid|Linoleic Acid|eicosapentaenoic acid ethyl ester|Eicosapentaenoic Acid|Docosahexaenoic Acids" 14 pdxdc1 25626431 Mol Nutr Food Res 2015 PMC4491005 10.1002/mnfr.201400734 18 8 4 62 "*Acids, Fatty|*Erythrocyte Membrane|eicosapentaenoic acid ethyl ester|Eicosapentaenoic Acid|Omega-3 Fatty Acids|Docosahexaenoic Acids|docosapentaenoic acid|Fatty Acids, Unsaturated|Fatty Acid Desaturases|Linoleic Acid|alpha-Linolenic Acid|Arachidonic Acid|*Plasma" 14 PRH2 26375204 J Proteomics 2015 10.1016/j.jprot.2015.09.009 7 6 0 19 "Humans|*Salivary Proline-Rich Proteins|*Proline|Salivary Proteins|Proline-Rich Protein Domains|Amino Acid Sequence|Protein Processing, Post-Translational|Glycosylation|Proteolysis|Alleles|Polymorphism, Genetic|Dimerization" 14 PRH2 25761918 J. Proteome Res. 2015 10.1021/pr501270x 5 1 1 19 "Infant|Adult|Infant, Newborn|Humans|Child, Preschool|Child|Adolescent|*Proteome|*Saliva|*Proteomics|Salivary Proteins|Spectrometry, Mass, Electrospray Ionization|Chromatography, High Pressure Liquid|Histatins|Infant, Premature|Cystatins|Phosphorylation|FAM20C protein, human|Extracellular Matrix Proteins|Casein Kinase I" 14 SIPA1L2 26678010 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2015 10.1002/ajmg.b.32410 3 0 0 65 "Humans|*Parkinson Disease|Genome-Wide Association Study|*Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Genetic Association Studies|Gene Frequency|Allele|Case-Control Studies|Age-at-Onset|Mainland China" 14 SIPA1L2 26364583 J. Neurochem. 2015 10.1111/jnc.13353 2 2 1 65 "Animals|Rats|*Synapses|Neurons|GTPase-Activating Proteins|Nerve Tissue Proteins|Disks Large Homolog 4 Protein|Adaptor Proteins, Signal Transducing|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Brain|Cells, Cultured|ProSAPiP1 protein, rat|Carrier Proteins" 14 SLC7A4 26662804 Tumour Biol. 2015 10.1007/s13277-015-4587-4 9 2 0 13 "Humans|*Autophagy|Autophagy-Related Proteins|Autophagosomes|Cysteine Endopeptidases|Microtubule-Associated Proteins|Cisplatin|*Lung Cancer|Cell Line, Tumor|Doxorubicin|Protein Binding|SLC27A4 protein, human|Fatty Acid Transport Proteins|ATG4B protein, human" 14 SLC7A4 26555760 Pflugers Arch. 2015 10.1007/s00424-015-1754-9 2 0 0 13 "Humans|*Cationic Amino Acid Transporters|*Fluorescence Resonance Energy Transfer|HEK293 Cells|Cationic Amino Acid Transporter 1|N,N-dimethylarginine|Arginine|Bacillus subtilis|Biological Transport|*Vibration" 14 STK32B 26308446 PLoS ONE 2015 PMC4550359 10.1371/journal.pone.0136360 1 2 1 8 "Chlorocebus aethiops|Animals|Humans|*DNA, Complementary|*Myristic Acid|System, Cellfree|Amino Acid Sequence|Protein Biosynthesis|Transfections|Protein Processing, Post-Translational|Mitochondria|Membrane Proteins|COS Cells|*Biochemical Phenomena" 14 STK32B 26083354 PLoS ONE 2015 PMC4471085 10.1371/journal.pone.0128688 11 14 0 8 "Sheep|Animals|*Breeding|*Genome|Sheep, Domestic|Genome-Wide Association Study|Phenotype|Polymorphism, Single Nucleotide|Meat|Red Meat" 14 STK32B 26079190 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2015 10.1002/ajmg.b.32330 28 0 1 8 "Humans|*Genome-Wide Association Study|Canada|*Suicidal Ideation|Suicide, Attempted|SNPs|Multifactorial Inheritance|Genetic Predisposition to Disease|Depressive Disorder, Major|Genotype|Genetic Markers|Case-Control Studies|TBX20 protein, human|T-Box Domain Proteins|ADAMTS14 protein, human|ADAMTS Proteins" 14 TESPA1 25736038 Clin. Rheumatol. 2015 10.1007/s10067-015-2900-7 1 1 0 97 "Humans|Animals|*Rheumatoid Arthritis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Gene Frequency|Genotype|Alleles|Case-Control Studies|Promoter Regions, Genetic|China|TESPA1 protein, human|Adaptor Proteins, Signal Transducing" 14 TTC28 26633546 Genet. Med. 2015 10.1038/gim.2015.147 10 0 1 73 "*Syndrome|*Genomics|Exome|Sequence Analysis, DNA|Genetic Testing|High-Throughput Nucleotide Sequencing|Phenotype|Pedigree|Mutation|*Cohort Studies" 14 TTC28 26561393 Hum. Genet. 2015 PMC4698300 10.1007/s00439-015-1606-x 8 5 1 73 "Humans|Animals|Mice|*Cleft Lip|*Cleft Palate|*DNA Copy Number Variations|Genome-Wide Association Study|Genetic Predisposition to Disease|Phenotype|Polymorphism, Single Nucleotide|*Cohort Studies|Genomics|Genes, Regulator|Transcription Factors|Genes, Homeobox|SATB2 protein, human|Matrix Attachment Region Binding Proteins" 14 WDPCP 26518167 Eur J Med Genet 2015 10.1016/j.ejmg.2015.10.011 6 0 0 51 "Humans|Bardet-Biedl Syndrome 12|Bardet-Biedl Syndrome 10|*Bardet-Biedl Syndrome|Group II Chaperonins|DNA Mutational Analysis|Genotype-Phenotype Correlation|Mutation|Polydactyly, Postaxial|Polydactyly|Phenotype|Pedigree|Genotype|Homozygote|Fingers|Toes|NPHP1 protein, human|Membrane Proteins|Adaptor Proteins, Signal Transducing" 14 WDPCP 26110142 Iran. J. Public Health 2015 PMC4475590 5 0 0 51 "Humans|Iran|Pilot Projects|*Diabetes Mellitus|Evidence-Based Medicine|Research Design|Middle East|bel1 protein, Human foamy virus|Retroviridae Proteins|Trans-Activators" 14 ZNF407 26102504 PLoS ONE 2015 PMC4477893 10.1371/journal.pone.0130149 1 1 0 21 "*Gastrointestinal Stromal Tumors|Proto-Oncogene Proteins c-kit|Receptor, Platelet-Derived Growth Factor alpha|*Mutation|Exon|Germline Mutation|Missense Mutation|Point Mutations" 14 ZNF407 25596527 J. Biol. Chem. 2015 PMC4358273 10.1074/jbc.M114.623736 6 5 2 21 "Animals|Mice|*Insulin|*mRNA|Diabetes Mellitus, Type 2|*Insulin, Regular, Human|Adipocytes|*Biological Transport|3T3-L1 Cells|Glucose|PPAR gamma|Signal Transduction|Cell Differentiation|Glucose Transporter Type 4|*Carbohydrate Metabolism|Zinc Fingers" 14 ZNHIT3 26210662 J. Mol. Biol. 2015 10.1016/j.jmb.2015.07.012 9 0 0 68 "Humans|*Saccharomyces cerevisiae|*Ribonucleoproteins, Small Nucleolar|Saccharomyces cerevisiae Proteins|Molecular Chaperones|Ribonucleoproteins, Small Nuclear|Nuclear Proteins|Transcription Factors|HSP90 Heat-Shock Proteins|Protein Binding|Ribosomes|RNA, Ribosomal|AAA ATPases|NUFIP1 protein, human|RNA-Binding Proteins|RPAP3 protein, human|Carrier Proteins|PIH1D1 protein, human|Apoptosis Regulatory Proteins" 14 ADGRA3 24902969 Andrology 2014 PMC4153397 10.1111/j.2047-2927.2014.00226.x 10 0 1 13 "Male|Adult|Humans|Mice|Animals|Adolescent|Young Adult|Middle Aged|Aged|*Testis|*Spermatogonia|Stem Cells|GPRC5C protein, human|Receptors, G-Protein-Coupled|*Biomarkers|Adult Stem Cells|Cell Differentiation|Inhibitor of Differentiation Proteins|*Inferior Colliculi|Adult Germline Stem Cells|*Organ Donors|Cadaver|ID4 protein, human|GPR125 protein, human" 14 ADGRA3 24864010 Fertil. Steril. 2014 10.1016/j.fertnstert.2014.04.022 13 0 2 13 "Male|Humans|*Testis|*Adult Germline Stem Cells|Spermatogonia|Cell Separation|Stem Cells|Cells, Cultured|Cell Differentiation|Integrin alpha6" 14 AP5B1 25455455 Toxicol. Lett. 2014 10.1016/j.toxlet.2014.09.030 2 0 0 411 14 B4GALNT3 25175058 J Proteomics 2014 10.1016/j.jprot.2014.07.013 5 0 0 74 *Mass Spectrometry|Carbohydrate Sequence|Oligosaccharides|*Ions|Glycans|Disaccharides|*Carbohydrate|Isomerism|Hexoses|*Gene Library 14 B4GALNT3 25003232 Oncotarget 2014 PMC4116512 10.18632/oncotarget.1981 19 30 5 74 14 B4GALNT3 24855066 Mol. Cell Proteomics 2014 PMC4159645 10.1074/mcp.M113.037085 43 0 7 74 14 B4GALNT3 24613754 Gene 2014 10.1016/j.gene.2014.02.058 4 0 3 74 14 C8orf37 25515582 Invest. Ophthalmol. Vis. Sci. 2014 PMC4296770 10.1167/iovs.14-15647 10 0 0 58 "*Cone-Rod Dystrophies|*Whole Exome Sequencing|Israel|*Retinal Cone|Retinitis Pigmentosa|DNA Mutational Analysis|Electroretinography|Retinal Degeneration|Pedigree|Genes, Dominant|Guanylate Cyclase|Mutations|Phenotypes" 14 C8orf37 25113443 Ophthalmic Genet. 2014 10.3109/13816810.2014.949380 5 0 0 58 "Humans|*Retinal Dystrophy|Retinitis Pigmentosa|*Cataracts|Electroretinography|Visual Field Tests|Genes, Recessive|DNA Mutational Analysis|Fluorescein Angiography|Visual Fields|Visual Acuity|Mutations|Pedigree|*Macular Degeneration|Tomography, Optical Coherence|Phenotype|*Myopia|Atrophy|C8orf37 protein, human" 14 C8orf37 24618324 Invest. Ophthalmol. Vis. Sci. 2014 10.1167/iovs.13-13567 19 0 4 58 Humans|*Whole Exome Sequencing|Thailand|*Retinitis Pigmentosa|DNA Mutational Analysis|Genotype-Phenotype Correlations|Eye Proteins|Pedigree|Exome|Mutation|Phenotype 14 CASC1 25118175 Nature 2014 10.1038/nature13733 74 0 9 21 "*Guide RNA|*Escherichia coli|Cryoelectron Microscopy|Clustered Regularly Interspaced Short Palindromic Repeats|CRISPR-Associated Proteins|CRISPR-Cas Systems|Escherichia coli Proteins|RNA, Bacterial|Nucleic Acid Conformation|Crystallography, X-Ray|Bacterial Proteins|Protein Binding|Models, Molecular|DNA|*Antigen-Antibody Complex" 14 CASC1 24860162 Cancer Res. 2014 PMC4102622 10.1158/0008-5472.CAN-13-3398 7 19 2 21 "Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Antineoplastic Agents|Mitotic Checkpoint|Paclitaxel|Mitosis|Spindle Apparatus|Apoptosis|Cell Line, Tumor|Microtubules|Cell Proliferation|Chromosome Segregation|*Cell Death" 14 CGB1 25063728 Fertil. Steril. 2014 10.1016/j.fertnstert.2014.06.016 1 2 0 4 "Humans|Female|Pregnancy|*Chorionic Gonadotropin, beta Subunit, Human|*Placenta|*Transcription Factor AP-2|*Promoter Regions, Genetic|Transcription, Genetic|DNA Methylation|RNA, Messenger|Miscarriages|TFAP2A protein, human" 14 CGB1 24778026 Anticancer Res. 2014 3 0 0 4 "Humans|Female|Pregnancy|*Chorionic Gonadotropin, beta Subunit, Human|Placenta|Transcription, Genetic|RNA, Messenger|*Biochemical Phenomena|Cancer|Cell Line" 14 DEPP1 25261981 Mol. Cancer 2014 PMC4197242 10.1186/1476-4598-13-224 12 56 2 108 "Humans|*Reactive Oxygen Species|*Neuroblastoma|Forkhead Box Protein O3|Apoptosis|Etoposide|Forkhead Transcription Factors|RNA, Small Interfering|Cell Survival|Cell Line, Tumor|FOXO3 protein, human|C10orf10 protein, human" 14 DEPP1 24936657 PLoS ONE 2014 PMC4061027 10.1371/journal.pone.0099730 0 1 0 108 "Female|Humans|*Prognosis|ERBB2 protein, human|Receptor, ErbB-2|Kaplan-Meier Analysis|Disease-Free Survival|Immunohistochemistry|Lymphatic Metastasis|Proportional Hazards Models|Biomarkers, Tumor|Multivariate Analysis|C10orf10 protein, human" 14 DEPP1 24530860 Biochim. Biophys. Acta 2014 10.1016/j.bbamcr.2014.02.003 9 3 0 108 "Humans|Chlorocebus aethiops|Mice|Animals|Vero Cells|*Autophagy|*Oxidative Stress|Reactive Oxygen Species|mRNA|Apoptosis|Cell Proliferation|Blotting, Western|*RNA|C10orf10 protein, human" 14 ELMOD2 24959202 Mol Cytogenet 2014 PMC4066825 10.1186/1755-8166-7-36 6 0 1 68 "Humans|Female|Comparative Genomic Hybridization|*Abnormalities, Multiple|Chromosome 4q- Syndrome|Chromosome Deletion|Chromosome Disorders|Chromosome 4, trisomy 4q|Trisomy|Craniofacial Abnormalities|Phenotype|*Hypertension, Pulmonary|Chromosomes, Human, Pair 4|PCDH18 protein, human|Cadherins|ELMOD2 protein, human|Cytoskeletal Proteins" 14 ELMOD2 24911211 PLoS ONE 2014 PMC4050054 10.1371/journal.pone.0099270 20 22 1 68 *GTPases|*Mitochondria|GTP-Binding Proteins|Cytoskeletal Proteins|Signal Transduction|*Cell Movement|Adenosine Triphosphate 14 ELMOD2 24616099 J. Biol. Chem. 2014 PMC4036250 10.1074/jbc.M114.548529 24 1 0 68 "Animals|Humans|*GTPase-Activating Proteins|HEK293 Cells|ADP-Ribosylation Factors|Cytoskeletal Proteins|*Cell Movement|Protein Transport|ARL2 protein, human|GTP-Binding Proteins|ELMOD2 protein, human" 14 GPR146 25163507 BMC Genomics 2014 PMC4153944 10.1186/1471-2164-15-716 20 3 4 25 "Pregnancy|Humans|Female|Infant, Newborn|Swine|Animals|*Methylation|Preterm Infants|*Intestine|Enterocolitis, Necrotizing|Animals, Newborn|Intestinal Microbiota|Intestinal Mucosa|Colostrum|Sus scrofa|Infant Formula|Premature Birth|*Parturition|Microbiota|Food, Formulated" 14 GPR146 25080497 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2014 10.1152/ajpregu.00206.2014 4 1 0 25 "Humans|*C-Peptide|*Insulin|*Diabetes Mellitus, Type 2|*Insulin, Regular, Human|*Erythrocytes|Erythrocyte Deformability|Adenosine Triphosphate|Peptides|Vasodilation|Muscle, Skeletal|Oxygen|Intercellular Signaling Peptides and Proteins" 14 GPR146 24503482 Mol. Phylogenet. Evol. 2014 10.1016/j.ympev.2014.01.022 20 4 3 25 "*Rhodopsin|*Phylogeny|HCAR3 protein, human|G-Protein-Coupled Receptors|Sequence Alignment|Evolution, Molecular|Ligands|neuromedin U 25|Neuropeptides|Signal Transduction|Software|Receptors, Nicotinic" 14 pdxdc1 25528277 BMC Genomics 2014 PMC4367882 10.1186/1471-2164-15-1155 9 1 2 62 "*DNA Copy Number Variations|*Exome|*Hearing Loss, Sensorineural|*Whole Exome Sequencing|Pedigree|*Genome Mapping|Mutations|Sequence Analysis, DNA|Deafness|Amino Acid Sequence|Mutation, Missense|Case-Control Studies" 14 pdxdc1 25401301 Nat. 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Biophys. Res. Commun. 2014 PMC4429777 10.1016/j.bbrc.2014.11.078 3 0 0 51 "Animals|*Actomyosin|*Cell Polarity|*Septins|WD repeat containing planar cell polarity effector|*Intracellular Signaling Peptides and Proteins|*Epithelial Cell|*Actin Cytoskeleton|Cilia|Cell Movement|Cytoskeleton|Xenopus Proteins|Xenopus laevis|Embryo, Nonmammalian|Plasma Membrane|Signal Transduction|*Cytoplasm" 14 WDPCP 25427950 Am. J. Med. Genet. A 2014 10.1002/ajmg.a.36852 7 0 2 51 "Humans|Female|*Heterozygote|*Aortic Coarctation|*Frameshift Mutation|*Polysyndactyly|*Hamartomas|Syndrome, Orofaciodigital|Mutation|*Aorta|Pedigree|Phenotype|*Tongue Neoplasms" 14 ZNF407 24907849 Orphanet J Rare Dis 2014 PMC4070100 10.1186/1750-1172-9-80 6 0 0 21 "*Zinc Finger|*Mutations|*Syndrome|Pedigree|Base Sequence|Abnormalities, Multiple|Amino Acid Sequence|Transcription Factors|Chromosome Mapping|Phenotype|Musculoskeletal Abnormalities|*Cognitive Impairment" 14 ZNHIT3 25404746 J. Cell Biol. 2014 PMC4242836 10.1083/jcb.201404160 24 37 3 68 "*Ribonucleoproteins, Small Nucleolar|*Proteomics|Ribonucleoproteins, Small Nuclear|Saccharomyces cerevisiae Proteins|snoRNA|Saccharomyces cerevisiae|Nuclear Proteins|DNA Helicases|Ribosomal Proteins|Cell Nucleolus|Adenosinetriphosphatase|Protein Binding" 14 ZNHIT3 25170085 Nucleic Acids Res. 2014 PMC4176330 10.1093/nar/gku612 17 33 2 68 "Humans|*Ribonucleoproteins, Small Nucleolar|Proteomics|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|RNA, U3 small nucleolar|Small Nucleolar RNA|ZNHIT3 protein, human|Nuclear Proteins|Ribonucleoproteins, Small Nuclear|Ribosomes|TYRP1 protein, human|Protein Binding|*Membrane Glycoproteins|Transcription Factors|RNA Binding Protein|NUFIP1 protein, human|PIH1 protein, S cerevisiae" 14 ZNHIT3 24596594 Int J Mol Epidemiol Genet 2014 PMC3939004 1 0 0 68 "*Sodium Chloride Symporter Inhibitors|*Hydroxymethylglutaryl-CoA Reductase Inhibitors|*Diabetes Mellitus, Type 2|*Diuretics|Hypertension|Risk Factors|Longitudinal Studies|*Gene Expression" 14 AAGAB 24289292 Clin. Exp. Dermatol. 2013 10.1111/ced.12213 1 0 0 66 "Humans|Adolescent|*Hip Dislocation, Congenital|*Keratoderma, Palmoplantar|*Mutations|Pedigree|Adaptor Proteins, Vesicular Transport|AAGAB protein, human" 14 AAGAB 23448244 Br. J. Dermatol. 2013 10.1111/bjd.12289 2 4 0 66 "Humans|*Keratoderma, Palmoplantar|*Chinese|*Mutation|Pedigree|Genetic Predisposition to Disease|Binding Protein|Adaptor Proteins, Vesicular Transport|AAGAB protein, human" 14 ADGRA3 23821037 Development 2013 PMC3699285 10.1242/dev.094839 16 2 1 13 "Animals|*Cell Polarity|Gastrulation|*Cell Signaling|Zebrafish Proteins|Zebrafish|Gastrula|Embryo, Nonmammalian|Dishevelled Proteins|Wnt Proteins|Adaptor Proteins, Signal Transducing|Cell Movement|Phosphoproteins|Gene Expression Regulation, Developmental|Membrane Proteins|Cell Membrane|Receptors, G-Protein-Coupled" 14 ALPK3 23792212 Mutat. 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Sci. 2013 PMC3820246 10.1242/jcs.133439 28 0 3 196 "*Cilia|*Chlamydomonas|Flagella|Chlamydomonas reinhardtii|Centrioles|Axoneme|TYRP1 protein, human|*Membrane Glycoproteins|Microtubules|Biological Transport|Signal Transduction" 14 CGB1 23774837 Int J Mol Sci 2013 PMC3709805 10.3390/ijms140612650 3 3 1 4 "Humans|Pregnancy|Female|*Chorionic Gonadotropin, beta Subunit, Human|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Placentas|Transcription, Genetic|Trophoblasts|RNA, Messenger|Upregulation" 14 GPR146 23980258 J. Endocrinol. 2013 0 2 0 25 "Humans|Animals|*C-Peptide|Diabetes Mellitus, Type 2|GPR160 protein, human|Receptors, G-Protein-Coupled|Signal Transduction|Diabetes Complications|Insulin|Cell Membranes" 14 GPR146 23759446 J. 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Cancer 2011 PMC3065289 10.1038/bjc.2011.61 9 1 0 15 "Humans|Child|*Meningioma|*Genetic Predisposition to Disease|*Linkage Disequilibrium|Meningeal Neoplasms|Radiation-Induced Cancer|Polymorphism, Single Nucleotide|*Chromosome Mapping|Brain Neoplasms|Genotype|Case-Control Studies|Ionizing Radiation|Risk Factor|Tinea Capitis|Israel" 14 PLEK2 21698244 PLoS ONE 2011 PMC3115966 10.1371/journal.pone.0020971 8 0 0 18 "Humans|*Transcriptome Profiling|*Melanoma|Oligonucleotide Array Sequence Analysis|MicroRNAs|RNA, Messenger|*Blood Cells|Biomarkers" 14 SIPA1L2 22178795 Toxicol. 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Genet. 2011 PMC3576836 10.1007/s00439-011-1009-6 38 5 3 8 "Humans|*Coronary Artery Disease|Genome-Wide Association Study|Single Nucleotide Polymorphisms|*Hypertension|Genetic Predisposition to Disease|Case-Control Studies|Genotype|Cardiovascular Disease|Gene Chip|Risk Factors|ZFAT protein, human|Transcription Factors" 14 TMUB1 21343306 J. Biol. Chem. 2011 PMC3083207 10.1074/jbc.M110.211326 36 41 2 225 "Animals|Humans|3-hydroxy-3-methylglutaryl-coenzyme A|HEK293 Cells|AMFR protein, human|*Receptors, Autocrine Motility Factor|Acyl Coenzyme A|UBB protein, human|*Ubiquitin|HMGCR protein, human|*HMG CoA Reductase|Ubiquitination|Endoplasmic Reticulum|Endoplasmic Reticulum-Associated Degradation|Ubiquitin-Protein Ligases|Sterols|Membrane Proteins|Protein Binding|Intracellular Signaling Peptides and Proteins|*Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent" 14 ZNHIT3 22178801 Fetal. Diagn. Ther. 2011 10.1159/000332968 6 0 0 68 "Pregnancy|Humans|Female|*Hernias, Diaphragmatic, Congenital|Chromosome Deletion|Abnormalities, Multiple|*Chromosome Disorders|Prenatal Diagnosis|Hepatocyte Nuclear Factor 1-beta|Karyotyping|TADA2A protein, human|Transcription Factors|Syndrome|In Situ Hybridization, Fluorescence|Adaptor Proteins, Signal Transducing|DUSP14 protein, human|Dual-Specificity Phosphatases|Mitogen-Activated Protein Kinase Phosphatases" 14 ADGRA3 21618837 Adv. Exp. Med. Biol. 2010 10.1007/978-1-4419-7913-1_16 2 0 0 13 "Male|Animals|Mice|Epididymis|Receptors, G-Protein-Coupled|*Male Reproductive System|Mice, Knockout" 14 B4GALNT3 20360844 PLoS ONE 2010 PMC2845611 10.1371/journal.pone.0009879 21 0 4 74 "*Genome-Wide Association Study|*Sudden Cardiac Arrest|*Locus, Genetic|Electrocardiography|Coronary Artery Disease|Case-Control Studies|Risk Assessment|Risk Factors|Polymorphism, Single Nucleotide" 14 CASC1 20639392 Hum. Mol. Genet. 2010 PMC3657480 10.1093/hmg/ddq303 59 0 2 21 "Humans|*Genome-Wide Association Study|*Heart Rate|Polymorphism, Single Nucleotide|Genetic Loci|Genome, Human|Risk Factors|Cardiovascular Disease|BCAT1 protein, human|Transaminases" 14 gltscr1 20150366 Neuro-oncology 2010 PMC2940551 10.1093/neuonc/nop012 46 0 4 33 "Adult|Humans|*Meningioma|*Neuroma, Acoustic|Case-Control Studies|*B-DNA|*Glioma|Primary Brain Tumors|Meningeal Neoplasms|XRCC1 protein, human|X-ray Repair Cross Complementing Protein 1|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|ERCC2 protein, human|Xeroderma Pigmentosum Group D Protein|xeroderma pigmentosum group F protein|DNA-Binding Proteins|DNA excision repair protein ERCC-5|DNA Repair|Genotype" 14 katnal2 21173776 Mol. Psychiatry 2010 PMC3785122 10.1038/mp.2010.128 92 0 3 15 Adult|Humans|*Genome-Wide Association Study|*Personality|Single Nucleotide Polymorphisms|Neuroticism|*Personality Disorders|Personality Inventory|Extroversion|Genotype 14 katnal2 20209439 Int. J. Dev. Biol. 2010 10.1387/ijdb.082778ag 1 0 0 15 "Humans|Mice|Male|Animals|Sperm Motility|Semen Analysis|*Mice, Inbred CBA|*Sperm|*Gene Mapping|*Mitochondria|Fertility|*Oxidation-Reduction|*Animals, Laboratory|KATNAL2 protein, mouse|Katanin" 14 PATL2 20826699 RNA 2010 PMC2957050 10.1261/rna.2295410 27 2 2 18 Humans|Animals|Xenopus laevis|Oogenesis|Xenopus Proteins|Oocytes|mRNA Cleavage and Polyadenylation Factors|mRNA|*Carrier Proteins|Protein Biosynthesis|Transcription Factors|Polyadenylation|3' Untranslated Regions|Amino Acid Sequence 14 PATL2 20471969 Dev. Biol. 2010 10.1016/j.ydbio.2010.05.006 13 1 0 18 "Humans|Animals|*Xenopus laevis|*Oocyte|Xenopus Proteins|Oogenesis|mRNA|mRNA Cleavage and Polyadenylation Factors|Protein Biosynthesis|messenger ribonucleoprotein|Ribonucleoproteins|RNA-Binding Proteins|Cyclin B1|*Protein Processing, Post-Translational|Transcription Factors" 14 STK32B 20087401 Eur. J. Hum. Genet. 2010 PMC2874614 10.1038/ejhg.2009.228 10 2 3 8 Humans|*Cleft Palate|Cleft Lip|Haplotypes|MSX1 Transcription Factor|Linkage Disequilibrium|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Genetic Linkage|Case-Control Studies|*Chromosome Structures|Taiwan|Republic of Korea|Maryland|Singapore 14 TMUB1 20582322 PLoS ONE 2010 PMC2889838 10.1371/journal.pone.0011261 7 2 0 225 "Animals|Mice|*Ubiquitin|*Wakefulness|CAMLG protein, human|*Adaptor Proteins, Signal Transducing|Carrier Proteins|Nuclear Proteins|Signal Transduction|Hepatocytes|Co-Immunoprecipitation|Cytoplasm|Cell Proliferation|Cell Line|Protein Transport|*Locomotor Activity" 14 ADGRA3 19846602 Biol. Reprod. 2009 PMC2809226 10.1095/biolreprod.109.078550 94 0 6 13 "Male|Adult|Humans|*Spermatogonia|Testes|Stem Cell|Cell Separation|Adult Stem Cells|Spermatids|Spermatocytes|POU5F1 protein, human|Octamer Transcription Factor-3|Cell Differentiation|Adult Germline Stem Cells|UCHL1 protein, human|Ubiquitin Thiolesterase|MAGEA4 protein, human|Antigens, Neoplasm|Neoplasm Proteins" 14 DEPP1 19937567 Horm. Metab. Res. 2009 10.1055/s-0029-1241841 7 5 0 108 "Humans|Mice|Rats|Animals|*Progesterone|Diabetes Mellitus, Experimental|*Adipose Tissue|B-insulin|*Insulin|*Liver|Adipocytes|mRNA|Fasting|Adipose Tissue, White|Gene Expression Regulation|3T3-L1 Cells|Adipogenesis|Adiponectin|Cell Differentiation|Muscle, Skeletal|Obesity|*Biotin" 14 ELMOD2 19966137 FASEB J. 2009 10.1096/fj.09-138545 21 4 2 68 "Humans|Nuclear Factor-Kappab|*Idiopathic Pulmonary Fibrosis|Toll-Like Receptor 3|Signal Transduction|Gene Expression|Cell Line|Epithelial Cells|Macrophages|Infections, Viral|Influenza A virus|Antiviral Agents|Transfection|Cytokines|ELMOD2 protein, human|Cytoskeletal Proteins" 14 gltscr1 19318434 Cancer Epidemiol. Biomarkers Prev. 2009 PMC2667563 10.1158/1055-9965.EPI-08-1078 32 1 0 33 "Adult|Humans|United States|*Glioblastoma|ERCC2 protein, human|Xeroderma Pigmentosum Group D Protein|DNA Repair|Haplotypes|Alleles|Brain Tumors|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|DNA-Binding Proteins|Case-Control Studies|Lung Neoplasms|Odds Ratio|San Francisco" 14 PLEK2 19372663 Cytogenet. Genome Res. 2009 10.1159/000200082 3 0 0 18 "Humans|myc Gene|Gene Amplification|*Cell Line|*Chromosome Structures|*Carcinoma|In Situ Hybridization, Fluorescence|Tumor Cells, Cultured|Chromosome Aberrations|VTI1B protein, human|Qb-SNARE Proteins" 14 ZNHIT3 19596656 Mol. Cell Proteomics 2009 PMC2758751 10.1074/mcp.M900209-MCP200 26 1 1 68 *PPAR gamma|Rosiglitazone|Thiazolidinediones|Transcription Factors|Adipocytes|Cell Differentiation|PPARalpha|Telmisartan|Corepressors|Benzoates|Hypoglycemic Agents|Ligands 14 BEX4 18236150 Biochem. Genet. 2008 10.1007/s10528-008-9148-8 8 0 1 64 14 CASC1 18560355 Oncogene 2008 10.1038/onc.2008.194 4 0 0 21 "Mice|Animals|*Genes, ras|*Mice, Inbred C57BL|*Lung Neoplasms|Genetic Susceptibility|HRAS protein, human|KRAS protein, human|Mouse Inbred Strains|Haplotype|Chromosome Mapping|Urethan|Polymorphism, Single Nucleotide|Alleles|*Genomics|Crosses, Genetic|Lung|*Regulatory Sequences, Nucleic Acid" 14 CASC1 18299280 Carcinogenesis 2008 10.1093/carcin/bgn048 9 0 1 21 "Humans|Mice|Animals|*Hyperplasia|*Proto-Oncogene Proteins p21(ras)|Case-Control Studies|*K-ras Oncogene|Bronchioloalveolar Carcinoma|*Lung Adenocarcinoma|*Precancerous Conditions|Lung Neoplasms|Adenocarcinoma|ras Proteins|ErbB Receptors|Lungs|*Polymorphism, Genetic|Mutation|Adenomas|KRAS protein, human" 14 CGB1 18606016 BMC Evol. Biol. 2008 PMC2478647 10.1186/1471-2148-8-195 7 0 0 4 "Pregnancy|Animals|Humans|Female|*Pan troglodytes|*Primate|*Hominidae|Gene Duplication|Genome, Human|Genomics|Evolution, Molecular|Gene Cluster|Chorionic Gonadotropin, beta Subunit, Human|Luteinizing Hormone|Genetic Variation|Luteinizing Hormone, beta Subunit|Chorionic Gonadotropin|Species Specificity" 14 STK32B 18454448 Hum. Mutat. 2008 10.1002/humu.20778 13 0 0 8 "Humans|*Ellis-Van Creveld Syndrome|Homozygote|Sequence Deletion|Pedigree|Heterozygote|Mutations|Phenotype|Tooth Abnormalities|Proteins|*Long Interspersed Nucleotide Elements|Intelligence|EVC2 protein, human|EVC protein, human" 14 TMUB1 18665261 PLoS ONE 2008 PMC2474703 10.1371/journal.pone.0002809 12 12 0 225 "Mice|Animals|*Receptors, AMPA|alpha Amino 3 hydroxy 5 methyl 4 isoxazolepropionic Acid|Neurons|Carrier Proteins|Synapses|Protein Transport|Plasma Membrane|Hippocampus|Synaptic Transmission|Cells, Cultured|*Hepatocyte|Cytoplasm|Ubiquitins" 14 ZNF407 18184143 Ann. Hum. Genet. 2008 10.1111/j.1469-1809.2007.00391.x 0 0 0 21 "Humans|*Nails|*Dysplasias, Ectodermal|Lod Score|*Hairs|Chromosome Mapping|Nails, Malformed|Genes, Recessive|Pedigree|Genetic Linkage|Hair Diseases|Phenotype|Genotype|*Chromosome 22|Microsatellite Markers|Pakistan" 14 BEX4 17638883 Cancer Res. 2007 10.1158/0008-5472.CAN-06-4394 40 15 4 64 14 CGB1 18048458 Mol. Hum. Reprod. 2007 PMC2628200 10.1093/molehr/gam082 13 0 0 4 "Pregnancy|Female|Male|Humans|*Chorionic Gonadotropin, beta Subunit, Human|*Trophoblasts|Placenta|Transcription, Genetic|mRNA|DNA Methylation|Chorionic Gonadotropin|Recurrent Miscarriages|Real Time PCR|Embryo Implantation|Genome" 14 ELMOD2 17452337 J. Biol. Chem. 2007 10.1074/jbc.M701347200 42 0 0 68 "Humans|Animals|Cattle|*GTPase Activating Protein|ADP-ribosylation factor 6|ADP-Ribosylation Factors|GTP-Binding Proteins|Cytoskeletal Proteins|ELMO1 protein, human|Adaptor Proteins, Signal Transducing|ELMO2 protein, human|ARL2 protein, human|ELMOD2 protein, human" 14 LCN8 17589789 Asian J. Androl. 2007 10.1111/j.1745-7262.2007.00300.x 6 3 0 2 "Mice|Animals|Male|*Epididymis|*Lipocalin|*Promoter Regions, Genetic|Mice, Transgenic|Gene Expression Regulation|DNA Sequence|AR protein, human|Androgen Receptor|Receptors, Retinoic Acid|Transgene|Regulatory Sequences, Nucleic Acid|Transcription Factor|Androgens|Retinol-Binding Proteins, Plasma|Gene Cluster|Transfection|Gene Expression|In Situ Hybridization" 14 PATL2 17848588 Mol. Cell Proteomics 2007 PMC2966871 10.1074/mcp.M700123-MCP200 43 0 9 18 "*Arabidopsis|*Brassinosteroids|*Proteomics|Chromatography, Liquid|Tandem Mass Spectrometry|Arabidopsis Proteins|Plant Hormones|Gene Expression Regulation, Plant|Steroids, Heterocyclic|Transcription Factors|Cholestanols|Signal Transduction|DNA-Binding Proteins|Nuclear Proteins|Phosphorylation|THI1 protein, Arabidopsis|BiP2 protein, Arabidopsis|Molecular Chaperones" 14 PLEK2 17658464 Biochem. Biophys. Res. Commun. 2007 10.1016/j.bbrc.2007.06.132 4 2 0 18 "*Actins|*Phosphatidylinositol 3-Kinase|platelet protein P47|*Phosphoproteins|*Blood Proteins|Phosphatidylinositol 3-Kinases|Phosphatidylinositol Phosphates|Cell Movement|Protein Transport|FN1 protein, human|Fibronectin" 14 PRH2 18037651 J. Dent. Res. 2007 10.1177/154405910708601207 7 0 0 19 "Child|Humans|Child, Preschool|*Proline|Salivary Proteins and Peptides|Salivary Proline-Rich Proteins|Proline-Rich Protein Domains|Alleles|TYRP1 protein, human|*Membrane Glycoproteins|Saliva|Gene Frequency|European Continental Ancestry Group|Streptococcus mutans|Exon|DNA|Polymorphism, Genetic|Electrophoresis, Polyacrylamide Gel|Phenotype" 14 SLC7A4 17417706 J. Membr. Biol. 2007 10.1007/s00232-006-0875-7 63 0 6 13 Animals|*Cationic Amino Acid Transporters|Biological Transport|Arginine|Amino Acids|Transport Proteins|Isoforms 14 CASC1 16862160 Nat. Genet. 2006 10.1038/ng1849 43 0 1 21 "Mice|Animals|*Whole Genome Association Analysis|Quantitative Trait Locus|*Lung Neoplasms|Chromosome Mapping|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Allele|Traits, Complex|Oncogene|Adenoma" 14 CASC1 16458428 Cancer Lett. 2006 10.1016/j.canlet.2005.12.015 1 2 0 21 "Mice|Humans|Animals|*Alleles|*Mice, Inbred C57BL|*Lung Cancer|*Lung|*Adenoma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Chromosome Mapping|Genes, ras|Haplotype|Urethane|*Cell Line" 14 CASC1 16410263 Carcinogenesis 2006 10.1093/carcin/bgi332 3 0 0 21 Humans|Mice|Animals|*Lung Cancer|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Adenocarcinoma|Genotype|Smoking|Adenoma|Lung Adenocarcinoma|Lung|Introns 14 CGB1 17055150 Mol. Cell. Endocrinol. 2006 PMC2599907 10.1016/j.mce.2005.11.049 17 1 0 4 "Humans|Animals|Female|Pregnancy|Chorionic Gonadotropin, beta Subunit, Human|*Genomics|Chorionic Gonadotropin|Luteinizing Hormone|Promoter Regions, Genetic|Gene Cluster|Transcription, Genetic|Chimpanzee" 14 CGB1 17004270 Med Res Rev 2006 10.1002/med.20076 4 0 0 4 "3-dehydroquinate dehydratase|HIV Infections|*Hydro-Lyases|Mycobacterium tuberculosis|Structure-Activity Relationship|Enzyme Inhibitors|Streptomyces coelicolor|Models, Molecular|Drug Design|Crystallography, X-Ray|Shikimic Acid|Antibiotics|Helicobacter pylori|Catalysis" 14 ELMOD2 16773575 Am. J. Hum. Genet. 2006 PMC1474126 10.1086/504639 31 0 2 68 "Humans|*Familial Idiopathic Pulmonary Fibrosis|Lung|Haplotype|Phenotype|Finland|ELMOD2 protein, human|Cytoskeletal Proteins" 14 LCN8 16935577 Biochim. Biophys. Acta 2006 10.1016/j.bbapap.2006.07.003 0 0 0 2 Humans|*Lipocalin|Escherichia coli|*Binding Site|Complement C8|*Ligands|Membrane Attack Complex|Complement C9|*Complement Protein|Protein Binding|Pore Forming Cytotoxic Proteins|Perforin|Membrane Glycoproteins|*Protein Domains|Dimerization 14 PLEK2 17008542 Blood 2006 PMC1785144 10.1182/blood-2006-02-001339 7 0 1 18 *Phosphatidylinositol 3-Kinase|platelet protein P47|*T Cells|*Phosphatidylinositol 3-Kinases|Phosphoproteins|Blood Proteins|Actin|Phosphatidylinositols|Cytoskeleton|Cell Membrane|Phosphorylation|Cell Adhesion|Membrane Proteins|Integrin alpha4beta1 14 SLC7A4 16904742 Placenta 2006 10.1016/j.placenta.2006.06.014 16 1 1 13 "Pregnancy|Humans|Female|*Serine|*Placenta|*Biological Transport|Amino Acid Transport System A|Syncytiotrophoblast|Microvilli|Amino Acids|2,2-dimethyl-beta-alanine|beta-Alanine|Cell Membrane|*Biochemical Phenomena|Membrane|Kinetics" 14 SLC7A4 16406416 J Ethnopharmacol 2006 10.1016/j.jep.2005.11.012 3 0 0 13 Humans|*Oligonucleotide Array Sequence Analysis|*Scutellaria baicalensis|*HEK293 Cells|Gene Expression Profiling|*Gene Expression|Gene Expression Regulation|Lipopolysaccharides|Inflammation Mediators|Plant Extracts|Inflammation|Scutellaria 14 ZNF407 16639285 Otol. Neurotol. 2006 10.1097/00129492-200604000-00022 6 0 0 21 "Humans|*Comparative Genomic Hybridization|Chromosome 18 deletion syndrome|Chromosome Deletion|Aural Atresia, Congenital|Karyotyping|Abnormalities, Multiple|Mental Retardation|In Situ Hybridization, Fluorescence|Phenotype|Ear Canal|Syndrome|Chromosomes, Human, Pair 18" 14 BEX4 15958283 Gene 2005 10.1016/j.gene.2005.05.012 28 5 1 64 14 BEX4 15870691 Oncogene 2005 10.1038/sj.onc.1208700 23 1 0 64 14 CGB1 16123088 Hum. Reprod. 2005 PMC1403819 10.1093/humrep/dei261 18 0 0 4 "Pregnancy|Humans|Female|Chorionic Gonadotropin, beta Subunit, Human|Recurrent Miscarriage|Ectopic Pregnancy" 14 DEPP1 16123073 Mol. Hum. Reprod. 2005 10.1093/molehr/gah186 11 7 0 108 "Humans|Female|Pregnancy|*ets-Domain Protein Elk-1|*Progesterone|*Protein A|*Stromal Cells|Endometrium|Decidua|Implantation, Embryo|mRNA|Cells, Cultured|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Gene Expression|Signal Transduction|Cell Differentiation|RU486|Hormone Antagonists" 14 gltscr1 16212814 Neuro-oncology 2005 PMC1871723 10.1215/S1152851705000037 22 0 1 33 "Adult|Humans|ERCC2 protein, human|*Xeroderma Pigmentosum Group D Protein|*Glioma|Endonucleases|Brain Neoplasms|DNA-Binding Proteins|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Transcription Factors|Nucleotide Excision Repair|Odds Ratios|Alleles|Whites|Glioblastoma|Case-Control Studies|Risk Factors" 14 gltscr1 15834925 Cancer 2005 10.1002/cncr.21028 19 0 1 33 "*Oligodendroglioma|Gliomas|Astrocytoma|ERCC2 protein, human|*Xeroderma Pigmentosum Group D Protein|Brain Neoplasms|NOP53 protein, human|Tumor Suppressor Proteins|Loss of Heterozygosity|*Transcription Factors|*Polymorphism, Genetic|Chromosome Deletion" 14 GPR146 15777626 Biochim. Biophys. Acta 2005 10.1016/j.bbagen.2004.12.001 17 1 1 25 "Humans|Rats|Mice|Animals|*Rhodopsin|Phylogeny|GPRC5C protein, human|G-Protein-Coupled Receptors|Evolution, Molecular|*Biological Evolution|TYRP1 protein, human|*Membrane Glycoproteins|Amino Acid Sequence|Expressed Sequence Tags|Fugu|GPR139 protein, human|Nerve Tissue Proteins" 14 PLEK2 15865208 Mol. Biol. Rep. 2005 10.1007/s11033-004-4747-x 0 0 0 18 "Humans|Animals|Mice|platelet protein P47|In Situ Hybridization, Fluorescence|Phosphoproteins|Amino Acid Sequence|cDNA|Base Sequence|Cloning, Molecular|Chromosome Mapping|Northern Blot|Membrane Proteins|Gene Expression|Sequence Homology, Amino Acid|*Chromosome" 14 SLC7A4 15746185 FASEB J. 2005 10.1096/fj.04-2924fje 7 1 0 13 "Humans|Mice|Animals|*Amino Acids|omega-N-Methylarginine|Nitric Oxide Synthase|NG-Nitroarginine Methyl Ester|*Enzyme Inhibitors|Leucine|Biological Transport|Nitric Oxide|Lysine|Macrophages|Cells, Cultured|Cells, Epithelial|*Cations|SLC7A7 protein, human|Fusion Regulatory Protein 1, Light Chains|SLC6A14 protein, human|Amino Acid Transport Systems, Neutral|Slc7a7 protein, mouse" 14 TMUB1 16014383 J. Cell. Sci. 2005 10.1242/jcs.02452 14 3 0 225 "*Hops|Liver Regeneration|*Protein Biosynthesis|Hepatocytes|Nuclear Proteins|Carrier Proteins|Hepatectomy|Liver|Signal Transduction Pathways|Cell Nucleus|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Cell Proliferation|Ubiquitin|RNA, Messenger|Growth Factors" 14 CGB1 15590838 Eukaryotic Cell 2004 PMC539015 10.1128/EC.3.6.1653-1663.2004 7 0 1 4 "*GTP-Binding Protein beta Subunits|*Virulence|*Cochliobolus|Fungal Proteins|Gene Expression Regulation, Fungal|Mitogen-Activated Protein Kinases|Maize|Plant Diseases|Hyphae|Signal Transduction Pathway|*Reproduction|*Morphogenesis|Conidia|GTP-Binding Proteins|Mutations" 14 CGB1 15138309 Physiol. Genomics 2004 10.1152/physiolgenomics.00104.2003 7 0 0 4 Humans|*Chromogranin B|*Pedigree|*Genetic Linkage|Lod Score|Quantitative Trait Locus|Chromosome Mapping|Microsatellite Markers|Chromogranins|Chromosome|Catecholamines 14 LCN8 15363845 Gene 2004 10.1016/j.gene.2004.06.027 17 0 1 2 "Humans|Male|Mice|Animals|*Epididymis|*Lipocalin|*Chromosomes, Human, Pair 2|Phylogeny|Amino Acid Sequence|Base Sequence|*Evolution, Molecular|Genome|Proteins|Gene Expression|Multigene Family|Promoter Regions, Genetic|RNA, Messenger|Receptors, Retinoic Acid" 14 LCN8 15197647 Cell Tissue Res. 2004 10.1007/s00441-004-0902-x 5 0 0 2 "Male|Humans|Mice|Animals|Adolescent|*Epididymis|*Testis|*Dihydrotestosterone|Lipocalin|*Gene Expression|Receptor Protein-Tyrosine Kinases|Proto-Oncogene Proteins|Orchiectomy|Excitatory Amino Acid Transporter 3|*Axon Initial Segment|GLB1 protein, human|beta-Galactosidase|*Biological Transport" 14 LCN8 15185139 Cell Tissue Res. 2004 10.1007/s00441-004-0892-8 4 0 1 2 "Male|Mice|Animals|*Lipocalin|*Epididymis|*Glutamate Transporter|GLB1 protein, human|*beta-Galactosidase|Testis|Receptor Protein-Tyrosine Kinases|Proto-Oncogene Proteins|*Ligations|Epithelium|*Protein Processing, Post-Translational|Glutamates" 14 LCN8 15059134 Br. J. Haematol. 2004 10.1111/j.1365-2141.2004.04877.x 16 0 1 2 "Humans|*Matrix Metalloproteinase 9|Tissue Inhibitor of Metalloproteinase-1|*Leukemia, Lymphocytic, Chronic, B-Cell|Matrix Metalloproteinase 2|Tissue Inhibitor of Metalloproteinase-2|Matrix Metalloproteinases|Type IV Collagen|Membranes, Basement|Cell Migration|Cell Adhesion|RNA, Messenger" 14 PATL2 15238540 Genetics 2004 PMC1470891 10.1534/genetics.104.028043 28 0 0 18 "*Arabidopsis|*Zinc|Arabidopsis Proteins|*RING Finger Domains|jasmonic acid|Oxylipins|Cyclopentanes|Salicylic Acid|Gene Expression Regulation, Plant|Ethylenes|E3 Ubiquitin Ligase|Zinc Fingers|Multigene Family|Sequence Homology, Amino Acid|DNA-Binding Proteins|Plant Diseases|Signal Transduction|Phenotype" 14 CGB1 14667226 J. Med. Chem. 2003 10.1021/jm030987q 0 0 0 4 "3-dehydroquinate dehydratase|*Streptomyces coelicolor|*Solid-Phase Synthesis Techniques|Molecular Docking Simulation|*Hydro-Lyases|Structure-Activity Relationship|Mycobacterium tuberculosis|Drug Design|Models, Molecular|Enzyme Inhibitors|Crystallography, X-Ray|Active Site" 14 CGB1 12636388 J. Org. Chem. 2003 10.1021/jo026692m 0 0 0 4 "*Quinic Acid|Molecular Structure|Oxidation-Reduction|Catalysis|Lactones|Stereoisomerism|Hydrolysis|Combinatorial Chemistry Techniques|Epoxy Compounds|Indicators and Reagents|Nuclear Magnetic Resonance, Biomolecular" 14 LCN8 14617364 Reprod. Biol. Endocrinol. 2003 PMC293424 10.1186/1477-7827-1-112 5 6 0 2 "Male|Animals|Humans|*Lipocalin|*Epididymis|Amino Acid Sequence|Base Sequence|Blotting, Northern|Spermatozoa|DNA, Complementary|Cloning, Molecular|Orchiectomy" 14 LCN8 12823123 Allergy 2003 10.1034/j.1398-9995.2003.00177.x 0 0 0 2 "Guinea Pigs|Animals|*Lipocalin|*Allergens|Immunoglobulin E|Hypersensitivity, Immediate|Cross Reactions|Immunoblotting|*Hair|Amino Acid Sequence|Epitopes|Electrophoresis, Polyacrylamide Gel|Sequence Homology, Amino Acid|*Vaccines" 14 LCN8 12586765 Endocrinology 2003 10.1210/en.2002-220932 4 1 0 2 "Rats|Humans|Male|Mice|Animals|*Epididymis|*Lipocalin|Testis|Amino Acid Sequence|Orchiectomy|Lcn5 protein, mouse|Retinol-Binding Proteins, Plasma|Receptors, Retinoic Acid|Sperm Maturation" 14 LCN8 12586764 Endocrinology 2003 10.1210/en.2002-220757 0 0 0 2 "Male|Mice|Animals|*Epididymis|*Transgene|*5' Flanking Region|Testis|Mice, Transgenic|Amino Acid Sequence|Promoter Regions, Genetic|Receptors, Retinoic Acid|Androgens|Retinol-Binding Proteins, Plasma|Carrier Proteins|DNA" 14 PATL2 12753931 FEBS Lett. 2003 10.1016/s0014-5793(03)00445-9 6 1 1 18 "Animals|*Zebrafish|SND1 protein, human|*Nuclear Proteins|TPX2 protein, human|*Cell Cycle Proteins|Nodal Signaling Ligands|Gastrula|Nodal Protein|Mesoderm|Zebrafish Proteins|Xenopus Proteins|*Embryogenesis|Embryo, Nonmammalian|*Signal Transduction|Body Patterning|Gene Expression Regulation, Developmental|*Microtubule-Associated Proteins|Transcription Factors" 14 gltscr1 12117772 Carcinogenesis 2002 10.1093/carcin/23.7.1149 8 0 1 33 "Humans|*Haplotypes|*Polymorphism, Single Nucleotide|*Basal Cell Carcinoma|Xeroderma Pigmentosum Group D Protein|Skin Neoplasms|Exon|*Chromosome 3|*Neoplasms, Basal Cell|Gene Frequency|Genotype|Intron|Transcription Factors|DNA-Binding Proteins|Nucleotide Excision Repair|Homozygote|European Continental Ancestry Group|Case-Control Studies|Denmark" 14 SLC7A4 12242592 Immunogenetics 2002 10.1007/s00251-002-0473-5 13 0 1 13 "Animals|*Zebrafish|Antiviral Agents|Hepatitis C, Chronic|*Histocompatibility Antigens Class II|Major Histocompatibility Complex|Genes, MHC Class II|Genes, MHC Class I|Base Sequence|Amino Acid Sequence|Genetic Linkage|Phylogeny|Genome" 14 SLC7A4 12049641 Biochem. J. 2002 PMC1222626 10.1042/BJ20020084 12 2 1 13 Humans|Animals|*Plasma Membrane|enhanced green fluorescent protein|Green Fluorescent Proteins|*Ion Transport|Carrier Proteins|Cationic Amino Acid Transporters|Amino Acid Transporter|Biological Transport|X. laevis|Amino Acid Sequence|Active Transport|Arginine|Luminescent Proteins|Oocytes|Substrate Specificity 14 CGB1 11368883 Cancer Lett. 2001 10.1016/s0304-3835(01)00496-7 9 2 1 4 "Humans|*Reverse Transcriptase Polymerase Chain Reaction|*Chorionic Gonadotropin, beta Subunit, Human|*Luteinizing Hormone, beta Subunit|*Gene Cluster|*Real-Time PCR, Quantitative|Chorionic Gonadotropin|Glycoprotein Hormones, alpha Subunit|mRNA|Trophoblasts|*Breast Cancer" 14 LCN8 11181548 Endocrinology 2001 10.1210/endo.142.3.8045 5 0 0 2 "Male|Mice|Animals|*Lipocalin|*Epididymis|*Gene Duplication|*Biotin|Lcn5 protein, mouse|Retinol-Binding Proteins, Plasma|Nucleotide Sequence|Mice, Transgenic|*Testis|Gene Expression|cDNA|Regulatory Sequences, Nucleic Acid|Amino Acid Sequence|Promoter Regions, Genetic|Receptors, Retinoic Acid|In Situ Hybridization|Multigene Family|Messenger RNA" 14 SLC7A4 11665818 Amino Acids 2001 10.1007/s007260170029 3 0 0 13 "Animals|Humans|*Cationic Amino Acid Transporter 1|SLC7A2 protein, human|*Amino Acid Transport Systems, Basic|Cationic Amino Acid Transporter 2|GIT2 protein, human|*GTPase-Activating Proteins|Arginine|*Genomics|Xenopus laevis|Biological Transport|Oocytes" 14 CASC1 10850665 Mol. 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Anim. Sci. 2020 PMC7097718 10.1093/jas/skaa068 0 0 0 160 Cattle|Animals|Genome-Wide Association Study|*Body Size|Quantitative Trait Loci|Haplotype|Single Nucleotide Polymorphisms|Phenotype|Chromosomes 13 LIMCH1 31959624 Life Sci Alliance 2020 PMC6971368 10.26508/lsa.201900623 1 0 0 160 "Humans|Epithelial-Mesenchymal Transition|*Cell Proliferation|Nuclear Pore Complex|Triple-Negative Breast Cancer|Nuclear Pore Complex Proteins|Cell Line, Tumor|Chromatin|Actin Cytoskeleton|Nup93 protein, human" 13 MIR193B 32596290 Biomed Res Int 2020 PMC7273449 10.1155/2020/2863236 0 0 0 0 "Humans|*Stomach Neoplasms|*Proto-Oncogene Proteins c-akt|*Apoptosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Downregulation|Cell Proliferation|*Stomach|Signal Transduction|Cell Line, Tumor|Genes, Tumor Suppressor" 13 MIR193B 32377743 Oncol. Rep. 2020 PMC7254955 10.3892/or.2020.7601 0 0 0 0 "*Osteosarcoma|MicroRNAs|Cell Proliferation|Stathmin|3' Untranslated Regions|Gene Expression Regulation, Neoplastic|Downregulation|Cell Movement|Cell Line, Tumor|*Neoplastic Processes|Upregulation|Apoptosis|Cell Transformation, Neoplastic|Cell Division" 13 PRSS35 32674273 Genes (Basel) 2020 10.3390/genes11070789 0 0 0 22 "Humans|*Aortic Valve|Heart Transplantation|Tissue Donors|*Aortic Valve Insufficiency|Aortic Stenosis|Calcinosis|*Constriction, Pathologic" 13 PRSS35 31920707 Front Physiol 2020 PMC6917667 10.3389/fphys.2019.01502 0 0 0 22 "Humans|*DNA Methylation|*Transcriptome|*Endothelial Cells|CpG Islands|*Transcriptome Analysis|Promoter Regions, Genetic|*Genome|Epigenesis, Genetic|*DNA|*Brain" 13 PRSS35 32674273 Genes (Basel) 2020 10.3390/genes11070789 0 0 0 22 "Humans|*Aortic Valve|Heart Transplantation|Tissue Donors|*Aortic Valve Insufficiency|Aortic Stenosis|Calcinosis|*Constriction, Pathologic" 13 PRSS35 31920707 Front Physiol 2020 PMC6917667 10.3389/fphys.2019.01502 0 0 0 22 "Humans|*DNA Methylation|*Transcriptome|*Endothelial Cells|CpG Islands|*Transcriptome Analysis|Promoter Regions, Genetic|*Genome|Epigenesis, Genetic|*DNA|*Brain" 13 RILPL2 32268075 Structure 2020 10.1016/j.str.2020.03.005 0 0 0 24 "*Parkinson Disease|*Phosphate|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|rab GTPases|Phosphorylation|*Cryopyrin-Associated Periodic Syndromes|*Biological Phenomena|Signal Transduction|*Recognition, Psychology|Mutation" 13 RILPL2 32017888 Structure 2020 PMC7139218 10.1016/j.str.2020.01.005 2 0 0 24 "*Phosphorylation|RAB8A protein, human|*rab GTPases|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|Parkinson Disease|Serine Threonine Kinase" 13 SFTA2 32351322 Mediators Inflamm. 2020 PMC7171686 10.1155/2020/5934821 0 0 0 275 "Humans|*Computational Biology|Reproducibility of Results|*Colorectal Cancer|*Prognosis|Protein Interaction Maps|Gene Ontology|*Carcinogenesis|Databases, Genetic|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Biomarkers, Tumor|Transcriptome|*Colonic Neoplasms|SLC26A3 protein, human|Sulfate Transporters|Chloride-Bicarbonate Antiporters" 13 SPECC1 32627938 Cancer Med 2020 10.1002/cam4.3219 0 0 0 213 "*Carcinoma, Hepatocellular|*Liver Neoplasms|*Tumorigenesis|MicroRNAs|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Cell Proliferation|*Transcription Factors|Downregulation|Hep G2 Cells|Cell Movement|Cell Line, Tumor|Apoptosis|*Autophagy|*Oxidative Stress|Disease Progression|RNAs, Circular" 13 SPECC1 32344305 Med. Hypotheses 2020 PMC7177071 10.1016/j.mehy.2020.109759 0 0 0 213 "Humans|severe acute respiratory syndrome coronavirus 2|COVID-19|*SARS Coronavirus|*Severe Acute Respiratory Syndrome|Betacoronavirus|Coronavirus Infections|Pneumonia, Viral|Pandemics|Peptidyl-Dipeptidase A|Genes, Regulator|Epigenesis, Genetic" 13 SRBD1 32569157 Medicine (Baltimore) 2020 PMC7310881 10.1097/MD.0000000000020066 0 0 0 43 "Humans|*Normal Tension Glaucoma|Republic of Korea|Allele Frequency|Genetic Susceptibility|Alleles|Glaucoma, Open Angle|Genotype|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Intraocular Pressure|Case-Control Studies|Cohort Studies|RNA-Binding Motifs" 13 SRBD1 32527613 Lung Cancer 2020 10.1016/j.lungcan.2020.04.031 0 0 0 43 "Humans|*Crizotinib|ALK protein, human|*Anaplastic Lymphoma Kinase|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Lung Adenocarcinoma|Receptor Protein-Tyrosine Kinases|Adenocarcinoma|Oncogene Proteins, Fusion|Protein Kinase Inhibitors|Gene Rearrangement|Pyrazoles|Pyridines|In Situ Hybridization, Fluorescence|Microtubule-Associated Proteins" 13 SRBD1 32010555 Transl Lung Cancer Res 2020 PMC6976381 10.21037/tlcr.2019.10.10 0 0 0 43 "Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|*Cell Proliferation|*Apoptosis|*Cell Cycle|Cell Line, Tumor|Gene Silencing|RNA, Small Interfering|Gene Expression Regulation, Neoplastic|RNA-Binding Motifs" 13 TENM1 32518679 Zoological Lett 2020 PMC7275387 10.1186/s40851-020-00159-3 0 0 0 81 "Animals|*Transcriptome|*Deprivation, Water|*Camelus|*Sodium Chloride|MicroRNAs|RNA, Messenger|*Sodium Chloride, Dietary|High-Throughput Nucleotide Sequencing|*Dehydration|*Ileum|Alternative Splicing|*Liver" 13 TENM1 32164602 BMC Cancer 2020 PMC7066786 10.1186/s12885-020-6676-z 0 0 0 81 "*Thyroid Nodule|Thyroid Carcinomas|Aspiration Biopsy, Fine-Needle|Adenocarcinoma, Follicular|Carcinoma, Papillary|Thyroid Gland|Carcinomas|Proto-Oncogene Proteins B-raf|*Biomarkers|Diagnosis, Differential" 13 TFDP3 32309437 Biomed Res Int 2020 PMC7142392 10.1155/2020/7082408 0 0 0 176 "Humans|*Epithelial-Mesenchymal Transition|*Prognosis|*Stomach Neoplasms|*Adenocarcinoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate" 13 tmem8c 31979341 Int J Mol Sci 2020 PMC7037418 10.3390/ijms21030745 0 0 0 4 Mice|Animals|eicosapentaenoic acid ethyl ester|*Eicosapentaenoic Acid|*Myoblasts|*Myotube|*Cell Differentiation|Myogenesis|*Gene Expression|Cell Line 13 ZNF385B 32277175 J. Hum. Genet. 2020 10.1038/s10038-020-0750-x 1 0 0 17 "Humans|Aged|Genome-Wide Association Study|*Age Related Macular Degeneration|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Genotype|Case-Control Studies|Retina|C4BPA protein, human|Complement C4b-Binding Protein" 13 ZNF385B 32079038 Br. J. Haematol. 2020 10.1111/bjh.16517 0 0 0 17 "Humans|*Multiple Myeloma|*Genes, Tumor Suppressor|DNA Methylation|miRNA|Epigenesis, Genetic|Promoter Regions, Genetic|Decitabine|Gene Expression Regulation, Neoplastic|Gene Silencing|Azacitidine|Cellular Proliferation|Cell Line, Tumor|Apoptosis|MIRN1258 microRNA, human" 13 BAIAP3 31200767 Clin Epigenetics 2019 PMC6570920 10.1186/s13148-019-0691-4 0 2 0 29 "Humans|*DNA Methylation|*B-DNA|*Adenoma|Colorectal Cancer|MutL Protein Homolog 1|Microsatellite Instability|Colonic Polyps|Proto-Oncogene Proteins B-raf|Biomarkers, Tumor|*Hyperplasia|Promoter Regions, Genetic|Colonic Neoplasms|Mutation|Gene Expression Regulation, Neoplastic|Phenotype" 13 BCL7C 31478280 J. Biochem. Mol. Toxicol. 2019 10.1002/jbt.22390 1 0 0 77 "Humans|Mice|Animals|*Receptors, Estrogen|Gene Expression Profiling|Insulin-Secreting Cells|Gene Ontology|Insulin Secretion|*Pancreas|Signal Transduction|Gene Expression|Transcription Factors|Estrogens|Mpv17 protein, mouse|Membrane Proteins" 13 CCDC141 31730661 PLoS ONE 2019 PMC6857912 10.1371/journal.pone.0224967 0 4 0 34 "Humans|Mice|Animals|IGBP1 protein, human|*Intracellular Signaling Peptides and Proteins|WWC1 protein, human|*Memory|*Phosphoproteins|Long-Term Potentiation|Receptors, AMPA|Hippocampus|*Cell Membrane|Neurons|Nerve Tissue Proteins|Binding Protein|*Cognition|Neurogenesis|Endocytosis|Memory Disorders" 13 CCDC141 30919020 Cell. Mol. Life Sci. 2019 PMC6529381 10.1007/s00018-019-03079-4 0 1 0 34 *Heart Rate|Genome-Wide Association Study|*Exercise|Autonomic Nervous System|Exercise Test|Rest|Cardiovascular System|Cardiovascular Diseases|Risk Factors|Genetic Linkage 13 CCDC141 30706161 Funct. Integr. Genomics 2019 PMC6570669 10.1007/s10142-019-00658-3 0 0 0 34 "Humans|*Polymorphism, Single Nucleotide|Twins, Dizygotic|*Cohort Studies|Genome-Wide Association Study|Genetic Predisposition to Disease|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|*Radiosensitivity|Twins, Monozygotic|*Genes, cdc|AKIP1 protein, human|Nuclear Proteins|Adaptor Proteins, Signal Transducing|CCDC141 protein, human|Nerve Tissue Proteins" 13 CCDC141 30617275 Mol. Psychiatry 2019 10.1038/s41380-018-0313-0 5 0 0 34 "Humans|*Genetic Loci|Genome-Wide Association Study|*Smoking Behavior|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Exome|Phenotype" 13 CCDC3 31750818 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2019 0 6 0 49 "Humans|*Bioinformatic|*Th1 Cells|Gene Ontology|Protein Interaction Maps|*Cell Differentiation|Th17 Cells|Gene Regulatory Networks|Gene Expression Profiling|Signal Transduction|Protein Interaction Mapping|Transcriptome|Software|Macrophages|Rheumatoid Arthritis|Interferon-gamma|IL17A protein, human|Interleukin 17A|Upregulation" 13 CCDC3 31083422 Genes (Basel) 2019 PMC6562665 10.3390/genes10050359 0 0 0 49 "Mice|Animals|*Mice, Obese|*Oxygen|*Adipose Tissue, White|*Inflammation|Obesity|Diet, High-Fat|Adipokines|Hypoxia|Mice, Inbred C57BL|*Biomarkers" 13 CCDC3 31081073 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201904_17680 0 3 0 49 "Female|Humans|*Epithelial-Mesenchymal Transition|*Uterine Cervical Neoplasms|Cell Movement|Neoplasm Invasiveness|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|HeLa Cells|Cadherins|RNA, Messenger" 13 CCDC3 30669351 Genes (Basel) 2019 PMC6356198 10.3390/genes10010061 3 1 0 49 "Animals|*Newcastle disease virus|Genome-Wide Association Study|*Chickens|Newcastle Disease|*Genomics|*Stress, Heat|Quantitative Trait Loci|*Heat Stress Disorders|Single Nucleotide Polymorphism|Gene Expression Profiling|Hot Temperature" 13 cmtr1 30768827 Chembiochem 2019 PMC6755138 10.1002/cbic.201900037 1 0 0 62 *Methylation|RNA Caps|Methyltransferases|Substrate Specificity|Guanosine|Giardia lamblia|Binding Sites|Viral Proteins|*Chemical Phenomena 13 cmtr1 30647901 Clin Transl Allergy 2019 PMC6327448 10.1186/s13601-018-0239-2 3 0 0 62 "Genome-Wide Association Study|*Corticosteroids|*Asthma|Administration, Inhalation|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pharmacogenetics" 13 CNTNAP3 31150793 Neurobiol. Dis. 2019 10.1016/j.nbd.2019.104486 0 2 0 49 "Male|Mice|Animals|neuroligin 1|Cell Adhesion Molecules, Neuronal|*Autism Spectrum Disorders|*Social Behaviors|CNTNAP1 protein, human|gephyrin|Membrane Proteins|Mice, Knockout|Nerve Tissue Proteins|Carrier Proteins|Social Interaction|Disease Models, Animal|Synapses|Learning, Spatial|Mutation|Phenotype" 13 CPAMD8 31877171 PLoS ONE 2019 PMC6932804 10.1371/journal.pone.0226823 0 0 0 5 "Cattle|Animals|*Cataracts|Lens, Crystalline|Pedigree|Phenotype|Mutation|Cattle Diseases|CPAMD8 protein, human|alpha-Macroglobulins|Complement C3|Trypsin Inhibitor, Kazal Pancreatic" 13 CPAMD8 31161422 Mol. Neurobiol. 2019 PMC6834745 10.1007/s12035-019-1630-2 1 0 0 5 "Humans|*Multiple Sclerosis|*Mutations|Whole Exome Sequencings|*Uveitis|Pedigree|Exome|Heterozygote|Genetic Linkage Analysis|Intermediate Uveitis|Homozygote|Siblings|CPAMD8 protein, human|alpha-Macroglobulins|Complement C3|Trypsin Inhibitor, Kazal Pancreatic" 13 DNAH10 31836722 Sci Rep 2019 PMC6910998 10.1038/s41598-019-53874-z 0 0 0 8 Humans|Adult|*Epidermis|Skin Transplantation|Skin|Burns|Dermis|Wound Healing|Granulation Tissue|Regeneration|Epidermal Cells|Cell Proliferation|*Inflammation 13 DNAH10 31102348 Mol Genet Genomic Med 2019 PMC6625361 10.1002/mgg3.729 2 0 0 8 "Pancreatic Carcinoma|*Pancreatic Cancer|*Prognosis|Carcinoma, Pancreatic Ductal|Biomarkers, Tumor|Gene Expression Profiling|Transcriptome|Kaplan-Meier Estimate|Gene Expression Regulation, Neoplastic|Databases, Genetic|Risk Factors" 13 DNAH10 30778226 Nat. Genet. 2019 PMC6560635 10.1038/s41588-018-0334-2 9 0 0 8 "Humans|*Body Fat Distribution|Allele Frequency|Waist to Hip Ratio|Exome|Genome-Wide Association Study|Genetic Predisposition to Disease|Body Mass Index|Polymorphism, Single Nucleotide|Genetic Variation|TYRP1 protein, human|*Membrane Glycoproteins|Phenotype|European Continental Ancestry Group|Lipids|*Homeostasis" 13 DNAH17 31841227 Ann. Hum. Genet. 2019 10.1111/ahg.12369 0 0 0 54 "Humans|Male|*Asthenozoospermia|*Sperm Flagellum|Infertility, Male|Spermatozoa|Teratozoospermia|*Multiple Abnormalities|Whole Exome Sequencing|Flagella|Cytoskeletal Proteins|Mutation" 13 DNAH17 31658987 J. Exp. Med. 2019 PMC7041708 10.1084/jem.20182365 1 0 0 54 "Humans|Male|Mice|Animals|*Asthenozoospermia|Sperm Flagellum|Infertility, Male|*Flagella|Spermatozoa|Axoneme|Sequencing, Whole Exome|Homozygote|Epididymis|Mutation|*Mutation, Missense|Testes" 13 DNAH17 31516583 Oncol Lett 2019 PMC6732947 10.3892/ol.2019.10730 1 0 0 54 "Humans|*lncRNA|*Prognosis|*Computational Biology|*Colorectal Cancer|*Oncogenesis|*Oncogenes|Kaplan-Meier Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Upregulation|Gene Expression Profiling|*Colonic Neoplasms|Multivariate Analyses" 13 DNAH17 31178125 Am. J. Hum. Genet. 2019 PMC6612517 10.1016/j.ajhg.2019.04.015 4 0 0 54 "Male|Humans|*Asthenozoospermia|DNAH9 protein, human|Axonemal Dyneins|Axoneme|*Infertility, Male|Kartagener Syndrome|*Sperm|Cilia|Sperm Flagellum|*Mutations|Flagella|Phenotype|Pedigree|Proteins|Alleles|Tubulin" 13 DNAH17 31103287 Fertil. Steril. 2019 10.1016/j.fertnstert.2019.03.020 1 2 0 54 "Humans|Male|*DNA Methylation|*B-DNA|*Infertility, Male|CpG Islands|Oligospermia|Azoospermia|Spermatozoa|Spermatogenesis|Fertility|Case-Control Studies" 13 DNAH17 30721949 Carcinogenesis 2019 10.1093/carcin/bgz013 1 0 0 54 "Mice|Animals|*DNA Mismatch Repair|Phosphatidylinositol 3-Kinases|MLH1 protein, human|MutL Protein Homolog 1|Mismatch Repair Endonuclease PMS2|Colorectal Neoplasms, Hereditary Nonpolyposis|*Mutations|KMT2D protein, human|DNA-Binding Proteins|MutS Homolog 2 Protein|Mutations, Germline|Microsatellite Instability|Nuclear Proteins|Mutations, Frameshift|Adaptor Proteins, Signal Transducing|Turcot syndrome|Colorectal Neoplasms|*Ionizing Radiation" 13 DNAJB5 31295760 Oral Dis 2019 10.1111/odi.13156 0 0 0 67 "*Leukoplakia, Oral|Mouth Neoplasms|Precancerous Conditions|Mouth Mucosa|*Hyperplasia|Carcinoma, Squamous Cell|Carcinoma in Situ|Biomarkers, Tumor" 13 DNAJB5 31001329 Front Genet 2019 PMC6454055 10.3389/fgene.2019.00300 0 0 0 67 "Swine|Animals|Sheep|*Selection, Genetic|*Genome|Breeding|Domesticated Animals|Mouflon|Phenotypes|Domestication|Phylogeny|Evolution, Molecular|Sus scrofa" 13 DSTYK 31201369 Lab. Invest. 2019 10.1038/s41374-019-0274-1 0 11 0 199 "*MAP Kinase Signaling System|Neoplasm Recurrence, Local|*Hemangiopericytoma|*Solitary Fibrous Tumors|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|STAT6 Transcription Factor|Brain Neoplasms|*Mutation|*Signal Transduction|Exome" 13 DSTYK 31047684 Acta Histochem. 2019 10.1016/j.acthis.2019.04.011 0 0 0 199 "Humans|FGFR2 protein, human|*Receptor, Fibroblast Growth Factor, Type 2|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|*Kidney|Ureter|Mesoderm|Signal Transduction|Apoptosis" 13 FNDC3A 31093274 Gastroenterol Res Pract 2019 PMC6481110 10.1155/2019/3784172 3 0 0 117 *Fibronectin Type III Domain|*Colorectal Cancer|*Inflammatory Bowel Disease|*Colonic Neoplasms|Intestinal Mucosa|*Fibronectin Type III Domain|*Colorectal Cancer|*Inflammatory Bowel Disease|*Colonic Neoplasms|Intestinal Mucosa 13 FNDC3A 31541092 Nat Commun 2019 PMC6754461 10.1038/s41467-019-11777-7 13 5 0 117 "Mice|Humans|Animals|*Vascular Endothelial Growth Factor A|*RNA, Circular|Endothelial Cells|*Myocardial Infarction|Cardiomyocytes|Myocardium|Myocardial Ischemia|Apoptosis|Neovascularization, Physiologic|Signal Transduction|Ventricular Functions, Left|Proto-Oncogene Proteins c-akt|Neovascularization, Pathologic|*Genes, Regulator|Cells, Cultured|*Cardiac Surgical Procedures|FUS protein, human|RNA-Binding Protein FUS" 13 FNDC3A 31527654 Sci Rep 2019 PMC6746793 10.1038/s41598-019-50055-w 1 0 0 117 "Animals|*Zebrafish|FN1 protein, human|*Fibronectins|Zebrafish Proteins|Animal Fins|Regeneration|Extremities|Gene Expression Regulation, Developmental|Extracellular Matrix|*Protein Domain" 13 FNDC3A 31479777 Theriogenology 2019 10.1016/j.theriogenology.2019.08.031 2 0 0 117 "Swine|Animals|Male|Female|Humans|*Genome-Wide Association Study|*Teratozoospermia|Semen|Semen Analysis|Sperm Motility|Artificial Insemination|Spermatozoa|Sus scrofa|Fertility|Phenotype|Spermatogenesis|Genes, Regulator|PELP1 protein, human|Transcription Factors|Co-Repressor Proteins|DICER1 protein, human|Ribonuclease III|DEAD-box RNA Helicases" 13 FOCAD 31814461 Scand. J. Gastroenterol. 2019 10.1080/00365521.2019.1697741 0 0 0 27 13 FOCAD 31510016 Cancers (Basel) 2019 PMC6770457 10.3390/cancers11091337 4 0 0 27 *Oncogenes|*Cell Culture|*Oncogenesis|Adenosine Diphosphate Ribose|*Cell Nucleus|Epithelial-Mesenchymal Transition|Pyrophosphatases|Hydrolysis|Nucleotides|*Immunologic Tests|Adenosine Triphosphate 13 FOCAD 31473790 Acta Neuropathol. 2019 10.1007/s00401-019-02067-z 1 2 0 27 "Humans|Homozygote|Sequence Deletion|*Gliomas, Astrocytic|Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Mutation|Genes, Tumor Suppressor|Promoter Regions, Genetic|*Disease Progression|Biomarkers, Tumor|Microtubules|FOCAD protein, human|Tumor Suppressor Proteins" 13 FOCAD 31243857 Hum. Mutat. 2019 10.1002/humu.23853 0 1 0 27 "Humans|*Prevalence|NTHL1 protein, human|*Deoxyribonuclease (Pyrimidine Dimer)|Adenomatous Polyposis Coli|*Colorectal Neoplasms|Mutations, Germline|Mutations|*Colon|Alleles|Genetic Predisposition to Disease|Phenotype|Mutation Frequency|MSH3 protein, human|MutS Homolog 3 Protein|MCM9 protein, human|Minichromosome Maintenance Proteins|FOCAD protein, human|Tumor Suppressor Proteins" 13 GLT8D1 31724708 Brain 2019 PMC7241952 10.1093/brain/awz358 2 0 0 18 *Glycosylation|Neurodegenerative Diseases|*Lipids|Amyotrophic lateral sclerosis 1|Amyotrophic Lateral Sclerosis|*Proteins|Glycosyltransferases|Acetylglucosamine|Alzheimer Disease|Polysaccharides|Mutations|Protein Domains|Oligosaccharides 13 GLT8D1 31653410 Neurobiol. Aging 2019 10.1016/j.neurobiolaging.2019.09.013 0 3 0 18 "Humans|*Amyotrophic Lateral Sclerosis|*DNA Mutational Analysis|Genetic Association Studies|Exon|Mutation|Genetic Predisposition to Disease|Genotype|Asian Continental Ancestry Group|Cohort Studies|Mainland China|GLT8D1 protein, human|Glycosyltransferases" 13 GLT8D1 31335339 Curr. Opin. Neurol. 2019 10.1097/WCO.0000000000000737 5 0 0 18 Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|Frontotemporal Dementia|T-Cell Intracellular Antigen-1|Genotype-Phenotype Correlation|Mutation|DNA-Binding Proteins 13 GLT8D1 31305325 Melanoma Res. 2019 10.1097/CMR.0000000000000631 1 0 0 18 "Humans|Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Prognosis|Immunohistochemistry|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Glycosyltransferases|Disease Progression|Upregulation|GLT8D1 protein, human" 13 GLT8D1 30811981 Cell Rep 2019 PMC7003067 10.1016/j.celrep.2019.02.006 4 0 0 18 Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Mutations|Exon|Superoxide Dismutase-1|Pedigree|Genetic Association Studies|Whole Exome Sequencing|*Glycosyltransferases 13 HSPB9 31546644 Toxics 2019 PMC6958418 10.3390/toxics7040050 0 0 0 26 Animals|*Propoxur|*Insecticides|*Zebrafish|*Larvae|Insecticide Resistance|Organophosphates|Embryonic Development|Pesticides|Carbamates 13 HYAL4 31298688 Genome Biol Evol 2019 PMC6685491 10.1093/gbe/evz149 0 0 0 7 Animals|*Birds|*Genome|Endangered Species|Inbreeding|Breeding|Population Size 13 HYAL4 31175155 J. Biol. Chem. 2019 PMC6663876 10.1074/jbc.RA119.008647 0 0 0 7 Humans|serglycin|*Chondroitin Sulfates|*Mast Cells|*Hyaluronoglucosaminidase|*Molecular Weight|*Cleavers|*Proteoglycan|*Vesicular Transport Proteins|Chondroitin Sulfate Proteoglycans|Heparin|Glycosaminoglycans|Aggrecan|Cytoplasmic Granules|*Cytokinesis 13 IQSEC3 31680123 Genet. Med. 2019 10.1038/s41436-019-0680-1 1 0 0 41 "Pena Shokeir syndrome, type 1|*Arthrogryposis|*Genomics|Pedigree|Mutation" 13 ITPRIP 31142202 Nucleus 2019 PMC6550788 10.1080/19491034.2019.1618175 2 0 0 920 "Humans|*Nuclear Envelope|*Proteomics|*Mesenchymal Stem Cells|Nuclear Pore Complex|*Membrane Proteins|*Organelles|Nuclear Proteins|Cell Fractionation|Subcellular Fractions|TMX4 protein, human|Membrane Glycoproteins|Protein Disulfide Reductase (Glutathione)" 13 LAMB4 30932413 Exp. Oncol. 2019 0 0 0 2 "Humans|*Primary Myelofibrosis|*DNA Copy Number Variations|Calreticulin|Receptors, Thrombopoietin|Janus Kinase 2|Loss of Heterozygosity|Oligonucleotide Array Sequence Analysis|Mutation" 13 LIMCH1 31279706 Gene 2019 10.1016/j.gene.2019.143963 1 8 0 160 "*Tumor Suppressor Protein p53|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Tumor Suppressor Proteins|Ubiquitin-Protein Ligases|Cell Proliferation|Apoptosis" 13 LIMCH1 31174455 Pediatr. Dev. Pathol. 2019 10.1177/1093526619852871 0 0 0 160 "Infant, Newborn|Pregnancy|Female|Humans|*Placentas|Fetal Growth Restriction|Placenta Diseases|Pre-Eclampsia|Infant, Small for Gestational Age|Chorionic Villi|Pregnancy Complications|Gestational Age" 13 MIR193B 31126198 Artif Cells Nanomed Biotechnol 2019 10.1080/21691401.2019.1620251 0 5 0 0 13 MIR193B 31002358 Oncol. Rep. 2019 PMC6489015 10.3892/or.2019.7108 4 7 0 0 "Humans|Female|*Support Vector Machine|Neoplasm Recurrence, Local|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|miRNA|Gene Expression Regulation, Neoplastic|Prognosis|Gene Regulatory Networks|Databases, Genetic|Gene Expression Profiling|MIRN211 microRNA, human|MIRN218 microRNA, human" 13 RASL11B 31432180 Mol Med Rep 2019 PMC6755162 10.3892/mmr.2019.10589 0 0 0 35 "Humans|*Up-Regulation|*Mitogen-Activated Protein Kinase 10|*Neuroblastoma|Gene Ontology|*Transcriptional Activation|Gene Regulatory Networks|Bioinformatics|Protein Interaction Maps|Gene Expression Regulation, Neoplastic|Protein Interaction Mapping|Neoplasm Proteins|Gene Expression Profiling|Transcription Factors|Biomarkers, Tumor|Transcriptome|Signal Transduction|Downregulation|TUBB2B protein, human" 13 RASL11B 31058255 Epigenet Insights 2019 PMC6452588 10.1177/2516865719839011 1 0 0 35 "Humans|thymoquinone|*Tumor Suppressor Genes|*Benzoquinones|*Epigenesis, Genetic|Apoptosis|Tumor Suppressor Proteins|Cell Line, Tumor|DNA-Binding Proteins|Jurkat Cells|Gene Expression Regulation, Neoplastic|Cell Proliferation" 13 RILPL2 31698103 J Proteomics 2019 10.1016/j.jprot.2019.103549 0 3 0 24 "Animals|Molecular Docking Simulation|MYO5A protein, human|Myosin V|Myosin Heavy Chains|Myosins|Binding Site|rab GTPases|Protein Binding|Actin|Models, Molecular|Biological Transport|Membrane" 13 RILPL2 31690808 Sci Rep 2019 PMC6831827 10.1038/s41598-019-52537-3 1 2 0 24 "*Leucine Zipper|Dynactin|Dynein|*Cytoskeleton|Adaptor Proteins, Signal Transducing|Microtubule-Associated Proteins|rab GTPases|Nerve Tissue Proteins|Protein Binding|Binding Site" 13 RILPL2 31497344 Am J Cancer Res 2019 PMC6726981 0 4 0 24 "Humans|Female|*Drug Resistance, Neoplasm|PTEN protein, human|*PTEN Phosphohydrolase|ERBB2 protein, human|Receptor, ErbB-2|Proto-Oncogene Proteins c-akt|Receptors, Estrogen|Phosphatidylinositol 3-Kinases|Cell Proliferation|Prognosis|Gene Expression Regulation, Neoplastic|*Tubulin|Lymphatic Metastasis|Apoptosis|Signal Transduction|Upregulation|*Neoplastic Processes|TUBB3 protein, human" 13 RILPL2 31175157 J. Biol. Chem. 2019 PMC6643029 10.1074/jbc.RA119.007384 0 1 0 24 "MYO5A protein, human|Myosin Type V|Myosin Heavy Chains|MLPH protein, human|*Adaptor Proteins, Signal Transducing|Binding Site|Melanosomes|Protein Binding|Protein Domains|Myosins|Actin|ATPase|Melanocytes|*Biochemical Phenomena|Motor Activity" 13 SFTA2 31487037 Clin. Exp. Immunol. 2019 PMC6857187 10.1111/cei.13367 0 0 0 275 "Humans|Genome-Wide Association Study|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Quantitative Trait Loci|*Lung|*Phenotype|Linkage Disequilibrium|Alleles|Genotype|Case-Control Studies|*Pneumonia|VARS2 protein, human|HLA Antigens|Valine-tRNA Ligase" 13 SFTA2 30882588 Ophthalmic Plast Reconstr Surg 2019 10.1097/IOP.0000000000001372 0 0 0 275 Humans|*Lacrimal Duct Obstruction|*Nasolacrimal Duct|Dacryocystorhinostomy|Lacrimal Apparatus|Epithelial Cells|Pulmonary Surfactant-Associated Proteins|Surface-Active Agents 13 SFTA2 30698415 Biochemistry 2019 PMC6566847 10.1021/acs.biochem.8b01280 2 1 0 275 "*Codon, Terminator|*RNA|*Eukaryotes|Ribosome|Protein Biosynthesis|mRNA|*Eukaryotic Cells" 13 SPECC1 31349968 Biochem. Biophys. Res. Commun. 2019 10.1016/j.bbrc.2019.07.065 2 19 0 213 "*Stomach Neoplasms|Downregulation|Cell Proliferation|MicroRNAs|*Transcription Factors|Gene Expression Regulation, Neoplastic|*Stomach|Up-Regulation|Cell Line, Tumor|*Neoplastic Processes|Apoptosis|*Genes, Regulator|siRNA|Cell Cycle|Disease Progression" 13 SPECC1 30854786 Vet Comp Oncol 2019 10.1111/vco.12475 0 0 0 213 13 SRRD 31674362 Appl Opt 2019 10.1364/AO.58.008069 0 0 0 66 *Nanostructures|Surface Plasmon Resonance|Refractometry|Nanoparticles|*Vibration|Computer Simulation|*Polymers 13 SRRD 30642986 J. Bacteriol. 2019 PMC6416917 10.1128/JB.00614-18 1 1 0 66 *Selenite|*Reductase|*Bacillus|Oxidation-Reduction|Bacterial Proteins 13 TENM1 31646573 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201910_19155 0 7 0 81 "*Thyroid Cancer, Papillary|*RNA, Micro|*Proto-Oncogene Proteins c-akt|*Cell Proliferation|*Downregulation|*Epithelial-Mesenchymal Transition|Thyroid Neoplasms|Carcinoma, Papillary|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Movement|*Signal Transduction|Cell Line, Tumor|Apoptosis" 13 tmem8c 31827673 Oxid Med Cell Longev 2019 PMC6885834 10.1155/2019/3585390 0 0 0 4 "NOX4 protein, human|*NADPH Oxidase 4|*Cell Differentiation|Myogenin|Myoblasts|MyoD Protein|Muscle Development|*Cell Communication|Regeneration|Cell Line|Myosin Heavy Chains|RNA, Small Interfering|Muscle, Skeletal" 13 tmem8c 31779203 Genes (Basel) 2019 PMC6947547 10.3390/genes10120970 0 0 0 4 "Animals|Cattle|*Transcriptome|*DNA Methylation|Epigenesis, Genetic|Genome|High-Throughput Nucleotide Sequencing|Muscle Development|Gene Expression Profiling|Promoter Regions, Genetic|Gene Expression Regulation, Developmental|*Paraspinal Muscles|Downregulation" 13 tmem8c 30892939 "Am. 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Genet. 2018 10.1007/s00439-018-1878-z 3 0 0 5 "Humans|CYP1B1 protein, human|*Cytochrome P-450 CYP1B1|*Hydrophthalmos|LTBP2 protein, human|Latent TGF-beta Binding Proteins|Glaucoma|Genetic Testing|DNA Mutational Analysis|Eye Proteins|Pedigree|Mutations|Cytoskeletal Proteins|Alleles|Haplotypes|Glycoproteins|*Optic Nerve Diseases|Cohort Studies|SLC4A11 protein, human" 13 DMRTA1 30016640 Dev. Biol. 2018 PMC6138557 10.1016/j.ydbio.2018.07.011 2 7 0 70 "Animals|*Neural Plate|Neural Crest|Ectoderm|Xenopus laevis|Xenopus Proteins|*Signal Transduction|*Embryonic Development|Embryo, Nonmammalian|SOX9 protein, human|SOX9 Transcription Factor|Cell Differentiation|Gene Expression Regulation, Developmental|SOXE Transcription Factors|*Catenins|Mesoderm" 13 DNAH10 29843777 Genome Med 2018 PMC5975672 10.1186/s13073-018-0549-y 3 7 0 8 Humans|Animals|*Heterotaxy Syndrome|*DNA Copy Number Variations|Body Patterning|Zebrafish Proteins|Zebrafish|Genetic Association Studies|Genotype 13 DNAH17 30575322 Cancer Med 2018 PMC6346260 10.1002/cam4.1930 2 2 0 54 "*Carcinoma, Hepatocellular|*Liver Neoplasms|CpG Islands|DNA Methylation|Epigenesis, Genetic|Promoter Regions, Genetic|Biomarkers, Tumor|Cell Line, Tumor" 13 DNAH17 29770609 Mol Genet Genomic Med 2018 PMC6081235 10.1002/mgg3.411 5 6 0 54 "*Blepharospasm|*Whole Exome Sequencing|Dystonia, Focal|Dystonia|Mutation" 13 DNAH17 29333154 Gastroenterol Res Pract 2018 PMC5733245 10.1155/2017/2029315 5 4 0 54 "*Carcinoma, Hepatocellular|*Hepatitis B virus|*Whole Exome Sequencing|*Liver Neoplasms|*Mutations|Hepatitis B|Exome|Cell Transformation, Neoplastic|China" 13 DNAJB12 30349556 Front Genet 2018 PMC6186841 10.3389/fgene.2018.00445 1 2 0 28 "Insect Proteins|DNAJB1 protein, human|HSP40 Heat-Shock Proteins|RNA Interference|Stress, Physiological|Antioxidants|Amino Acid Sequence" 13 DSTYK 29409666 Acta Histochem. 2018 10.1016/j.acthis.2018.01.008 6 0 0 199 "Animals|Humans|*Fibroblast Growth Factor 2|*Limbs|Mesenchyme|Ectoderm|Limb Buds|Homeodomain Proteins|MSX1 Transcription Factor|Morphogenesis|HNF1A protein, human|*Hepatocyte Nuclear Factor 1-alpha|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|Gene Expression Regulation, Developmental|Fibroblast Growth Factors|CASP3 protein, human|Caspase 3|Cell Proliferation|Cell Differentiation" 13 EMC10 29884787 Sci Rep 2018 PMC5993790 10.1038/s41598-018-26274-y 5 0 0 130 "Humans|*Whole Exome Sequencing|*Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Exome|Alleles|Pedigree|Autoimmune Diseases|Genotype|Iceland" 13 EMC10 29659949 J Mol Cell Biol 2018 10.1093/jmcb/mjy024 3 2 0 130 "Humans|Male|Animals|Mice|Sperm Motility|*Sperm|Acrosome Reaction|Sperm Capacitation|Infertility, Male|Fertilization|Fertility|Sodium-Potassium-Exchanging ATPase|Oocytes|Membrane Proteins|Phosphorylation|Emc10 protein, mouse" 13 FKBP2 30487748 Front Pharmacol 2018 PMC6246626 10.3389/fphar.2018.01296 0 0 0 95 "*Kidney Transplantation|*Calcineurin|Tacrolimus|Immunosuppressive Agents|Mycophenolate Sodium|Calcineurin Inhibitors|MTOR protein, human|*TOR Serine-Threonine Kinases|Graft Rejection|Everolimus|*Signal Transduction|Polymorphism, Single Nucleotide|Brazil" 13 glocose 29392616 Endocrine 2018 10.1007/s12020-018-1525-4 7 1 0 0 "Animals|kaempferol|*Kaempferols|*Oxidative Stress|Diabetic Cardiomyopathy|*Hyperglycemia|Antioxidants|NF-E2-Related Factor 2|Inflammation|NF-kappa B|Diabetes Mellitus, Experimental|Reactive Oxygen Species|Myocytes, Cardiac|Anti-Inflammatory Agents|Signal Transduction|Apoptosis|Glucose|*Heart Injuries|Cell Line" 13 GLT8D1 30446647 Nat Commun 2018 PMC6240073 10.1038/s41467-018-07401-9 0 0 0 18 "*Schizophrenia|*Genes, Regulator|*Risk Factors|Academy|Science, Life|China|Serogroup|Universities" 13 GLT8D1 30030838 J. 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Biol. 2018 PMC6158017 10.1016/j.ydbio.2018.07.005 5 0 0 108 "Mice|Animals|*Transcription Factors|*Neurons|Telencephalon|*Ganglia|Homeodomain Proteins|OLIG2 protein, human|Oligodendrocyte Transcription Factor 2|Oligodendroglia|Neural Stem Cells|*Neuroglia|Cell Differentiation|Gene Expression Regulation, Developmental|Embryo, Mammalian" 13 GSX1 29869716 Cell Tissue Res. 2018 10.1007/s00441-018-2859-1 5 0 0 108 "Rats|Mice|Animals|*Hypothalamus|*Neuroendocrine System|*Neurons|Supraoptic Nucleus|Paraventricular Hypothalamic Nucleus|transcription factor Brn-2|Homeodomain Proteins|Pituitary Gland, Posterior|POU Domain Factors|Arcuate Nucleus|Medial Eminence|Axons|*Mammals|Transcription Factors|Sim1 protein, mouse|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Dbx1 protein, mouse" 13 HSPB9 30335980 Environ. Sci. 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Rheumatol. 2018 10.1007/s10067-018-4278-9 2 0 0 2 "*Mendelian Randomization Analysis|Genome-Wide Association Study|*Coffee|*Rheumatoid Arthritis|*Lupus Erythematosus, Systemic|Single Nucleotide Polymorphisms|CYP1A1 protein, human|CYP1A1" 13 LAMB4 29739312 BMC Genomics 2018 PMC5941690 10.1186/s12864-018-4747-1 5 0 0 2 "Sheep|Animals|*Transcriptome Analysis|*Breeding|*Adipose Tissue|Sequencing, RNA|Transcriptome Profiles|High-Throughput Nucleotide Sequencing|Lipid Metabolism|Sheep, Domestic|Meat|Phenotype" 13 LIMCH1 30429017 Lung Cancer 2018 10.1016/j.lungcan.2018.09.017 1 3 0 160 "Humans|*Prognosis|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Integral Membrane Proteins|Membrane Glycoproteins|Biomarkers, Tumor|Genes, Tumor Suppressor|Downregulation|LMO7 protein, human|Transcription Factors|LIM Domain Proteins|LRIG1 protein, human|LIMCH1 protein, human" 13 LIMCH1 29315579 J. Physiol. 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Metab. 2017 PMC5470764 10.1210/jc.2016-3391 3 2 0 34 Idiopathic Hypogonadotropic Hypogonadism|*Hypogonadism|Kallmann Syndrome|*Mutations|Gonadotropin Releasing Hormone|Nerve Tissue Proteins|Phenotype|Extracellular Matrix Proteins|Neurons 13 CCDC3 28827783 Sci Rep 2017 PMC5566403 10.1038/s41598-017-09228-8 3 45 0 49 "Mice|Animals|*Lipid Metabolism|Trans-Activators|*Liver|Phosphoproteins|Transcription Factors|Fatty Liver|Tumor Suppressor Proteins|Cell Differentiation|Cell Line|Mice, Transgenic" 13 cmtr1 28971629 Wiley Interdiscip Rev RNA 2017 PMC7169794 10.1002/wrna.1450 5 1 0 62 *Methylation|methylcobalamin-coenzyme M methyltransferase|Methyltransferases|RNA Caps|mRNA|RNA Splicing|Ribose|Guanosine|Nucleotides|Archaeal Proteins 13 CNTNAP3 29090003 Neural Regen Res 2017 PMC5649478 10.4103/1673-5374.215268 4 10 0 49 "CNTNAP1 protein, human|*Cell Adhesion Molecules, Neuronal|*Axons|CNTNAP2 protein, human|Nerve Tissue Proteins|Neurons|Membrane Proteins|Nerve Fibers, Myelinated|Synaptic Transmission|*Nervous System Diseases|Multiple Sclerosis|Contactins" 13 CNTNAP3 28413940 Nord J Psychiatry 2017 10.1080/08039488.2017.1291720 1 0 0 49 "Humans|Animals|Mice|*Schizophrenia|Antipsychotic Agents|Brain|Leukocytes|RNA, Messenger|Caspr3 protein, mouse|Membrane Proteins|Nerve Tissue Proteins" 13 CPAMD8 28683140 PLoS ONE 2017 PMC5500361 10.1371/journal.pone.0180665 2 0 0 5 "Cattle|Animals|*Codon, Nonsense|Genome-Wide Association Study|*Cataracts|Lens, Crystalline|*Mammals|Pedigree|Mutation" 13 DNAJB12 31251138 J Biomed Nanotechnol 2017 10.1166/jbn.2017.2380 0 0 0 28 "Rats|Animals|*Nanofibers|*PC12 Cells|*mRNA|*Cell Differentiation|Polyesters|Tissue Scaffolds|Lactic Acid|Polymers|RNA, Micro|Cell Proliferation|Cell Adhesion" 13 DNAJB12 28536268 J. 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Chem. 2017 PMC5512073 10.1074/jbc.M117.785113 4 4 0 28 "Humans|*Endoplasmic Reticulum Stress|*Endoplasmic Reticulum|*Apoptosis|DNAJB1 protein, human|HSP40 Protein Family|Endoplasmic Reticulum-Associated Degradation|Hepatoma|Unfolded Protein Response|CASP3 protein, human|Caspase 3|Liver Neoplasms|Proteasome|Protein Folding|Signal Transduction|Cytosol|Molecular Chaperones|HSP70 Heat-Shock Proteins|DNAJB12 protein, human" 13 DNAJB5 29113809 Gastroenterology 2017 PMC5863695 10.1053/j.gastro.2017.10.043 15 17 0 67 "*Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|*Antineoplastic Agents|Xenograft Model Antitumor Assays|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Heat-Shock Proteins" 13 DNAJB5 28380666 Hippocampus 2017 PMC5501956 10.1002/hipo.22731 4 8 0 67 "Humans|*MAP Kinase Signaling System|WWC1 protein, human|*Intracellular Signaling Peptides and Proteins|*Phosphoproteins|*Hippocampus|Episodic Memory|Genotype|Alzheimer Disease|Polymorphism, Single Nucleotide|Neuropsychological Tests|*Transcriptome Profiling|Learning|Cognition" 13 DSTYK 29261186 Genet. Med. 2017 10.1038/gim.2017.173 4 0 0 199 "Hereditary renal agenesis|*Kidney|Renal Adysplasia|*Urogenital Abnormalities|*Kidney Diseases|Limb Deformities, Congenital|Anus, Imperforate|Trachea|Anal Canal|Esophageal Atresia|Esophagus|*Solitary Kidney|*Mutations|Spine|Abnormalities, Multiple|Heart Defects, Congenital|Phenotype|*Genomics" 13 DSTYK 28618409 Am. J. Nephrol. 2017 10.1159/000477590 1 0 0 199 Humans|*Solitary Kidney|Branchio-Oto-Renal Syndrome|*Asian Continental Ancestry Group|Mutations|Hepatocyte Nuclear Factor 1-beta|Homeodomain Proteins|Nuclear Proteins|Intracellular Signaling Peptides and Proteins|Genetic Predisposition to Disease|Phenotype|Cohort Studies 13 DSTYK 28566479 J. Am. Soc. Nephrol. 2017 PMC5619971 10.1681/ASN.2017010043 23 0 0 199 Child|Humans|Mice|Animals|*Exome|*Whole Exome Sequencing|Urogenital Abnormalities|Urinary Tract|Vesico-Ureteral Reflux|Kidney|Mutations|High-Throughput Nucleotide Sequencing|Phenotypes|Fetus 13 DSTYK 28157540 Am. J. Hum. Genet. 2017 PMC5294675 10.1016/j.ajhg.2017.01.014 6 1 0 199 "Animals|Mice|*Paraparesis, Spastic|Spastic paraplegia 23|*Spastic Paraplegia, Hereditary|Pigmentation Disorders|Pedigree|*Facies|*Vitiligo|Genetic Linkage|Homozygote|Mutation|Exons" 13 EMC10 28931551 Circulation 2017 10.1161/CIRCULATIONAHA.117.029980 3 1 0 130 "Humans|Animals|*Bone Marrow|*Myocardial Infarction|Ventricular Remodeling|Myocardium|Ventricular Function, Left|*Intercellular Signaling Peptides and Proteins|Neovascularization, Physiologic|Signal Transduction|Disease Models, Animal|Apoptosis|Membrane Proteins|Endoplasmic Reticulum" 13 EMC10 28696314 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5544257 10.1073/pnas.1615719114 9 0 0 130 "Animals|Humans|Schizophrenia|Neuronal Plasticity|Hippocampus|Brain|Disease Models, Animal|Loss of Function Mutation|DiGeorge Syndrome|*Mutation|Genetic Predisposition to Disease" 13 FKBP2 28429845 Biotechnol J 2017 10.1002/biot.201600631 3 0 0 95 "*Saccharomyces cerevisiae|*Plasma Cells|Saccharomyces cerevisiae Proteins|glucose-regulated protein 170|HSP70 Heat-Shock Proteins|molecular chaperone GRP78|Heat-Shock Proteins|Peptidylprolyl Isomerase|Molecular Chaperones|Protein Folding|Recombinant Proteins|Protein Disulfide-Isomerases|*Production, Antibody|Endoplasmic Reticulum|Glycoproteins|*Protein Transport|Antibodies" 13 FKBP2 28385890 J. Biol. Chem. 2017 PMC5454108 10.1074/jbc.M116.772657 4 0 0 95 "Humans|*Hydroxyproline|*Endoplasmic Reticulum|Rough Endoplasmic Reticulum|Protein Folding|Protein Structure, Secondary|Collagen|Cyclophilins|Molecular Chaperones|Collagen Type I|Extracellular Matrix Proteins|Tacrolimus Binding Proteins|Extracellular Matrix|Proline" 13 FKBP2 28152021 PLoS ONE 2017 PMC5289589 10.1371/journal.pone.0171232 2 4 0 95 "*Calgranulin B|Colon Cancer|Gastric Cancer|Cell Line, Tumor|Cell Proliferation|Tumor Microenvironment|*Gastrointestinal Cancer|Colon" 13 FOCAD 29031776 Gene 2017 10.1016/j.gene.2017.10.030 0 5 0 27 "Male|Humans|Animals|Mice|*Haplotypes|*Risk Factors|Plaque, Atherosclerotic|Genetic Predisposition to Disease|*Atherosclerosis|Polymorphism, Single Nucleotide|Coronary Artery Disease|Genotypes|Carotid Artery Diseases|Gene Frequency|Myocardial Infarction|Phenotypes|Cholesterol, LDL|Case-Control Studies|Serbia|FOCAD protein, human|Tumor Suppressor Proteins" 13 GLT8D1 28720891 Sci Rep 2017 PMC5515956 10.1038/s41598-017-06033-1 15 0 0 18 "Humans|*Whole Exome Sequencing|*Autism Spectrum Disorder|Saudi Arabia|Exome|Genetic Predisposition to Disease|Disorder, Neurodevelopmental|Mutation|Intellectual Disability|GLT8D1 protein, human|Glycosyltransferases" 13 ITPRIP 28704393 PLoS ONE 2017 PMC5509141 10.1371/journal.pone.0180046 1 16 0 920 "Middle Aged|Humans|*Exome|*European Continental Ancestry Group|Genome-Wide Association Study|African Americans|*Atherosclerosis|*Amyloidogenic Proteins|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|*Amyloidosis|*Plasma" 13 LAMB4 28595269 Hum. Mol. Genet. 2017 PMC6251658 10.1093/hmg/ddx204 6 0 0 2 "Humans|*Whole Exome Sequencing|*Exome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Pedigree|Sequence Analysis, DNA|*Diverticulitis|Laminin" 13 LIMCH1 28377053 Artif Intell Med 2017 10.1016/j.artmed.2017.03.010 7 0 0 160 "Humans|*Transcription Factors|*Lung Adenocarcinoma|Adenocarcinoma|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Computational Biology|Gene Expression Profiling|Cell Transformation, Neoplastic|Databases, Genetic|Cell Proliferation" 13 LIMCH1 28228547 Mol. Biol. 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Dyn. 2017 PMC6322676 10.1002/dvdy.24512 4 3 0 35 "Animals|*Zebrafish|*Signal Transduction|Semaphorins|plexin|Nerve Tissue Proteins|Zebrafish Proteins|Receptors, Cell Surface|Cell Movement|Cell Adhesion Molecules|Gene Expression Regulation, Developmental|Retina|Sema6a protein, zebrafish" 13 RILPL2 29125462 Elife 2017 PMC5695910 10.7554/eLife.31012 69 52 0 24 "Animals|Mice|*Phosphorylation|*Proteomics|Rab12 protein, human|rab GTPases|Leucine-Rich Repeat Serine-Threonine Protein Kinase-2|RAB8A protein, human|Signal Transduction|Parkinson Disease|Cilia|Protein Transport" 13 RILPL2 28600779 Hum. 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Biol. 2017 10.1016/bs.ctdb.2016.08.007 4 0 0 6 "Animals|Humans|*Gene Regulatory Networks|Brachyury protein|Fetal Proteins|T-Box Domain Proteins|Ciona intestinalis|Notochord|Gene Expression Regulation, Developmental|Invertebrate Chordates|Transcription Factors|Biological Evolution|Morphogenesis|In Situ Hybridization" 13 TFDP3 28797103 PLoS ONE 2017 PMC5552311 10.1371/journal.pone.0182781 1 12 0 176 "Humans|Male|*Hep G2 Cells|*Testis|*Cell Cycle Checkpoints|Transcription Factor DP1|Apoptosis|E2F1 Transcription Factor|Carcinoma, Hepatocellular|Cell Line, Tumor|Cell Proliferation|Gene Expression Regulation, Neoplastic|G1 Phase|Liver Neoplasms|TFDP3 protein, human" 13 TFDP3 28114432 PLoS ONE 2017 PMC5256886 10.1371/journal.pone.0170573 3 5 0 176 "Humans|Male|Female|*Epithelial-Mesenchymal Transition|Transcription Factor DP1|Hepatocellular Carcinoma|Cell Proliferation|E2F1 Transcription Factor|Cell Line, Tumor|MCF-7 Cells|Lymphatic Metastasis|Liver Neoplasms|Tumor Microenvironment|TFDP3 protein, human" 13 tmem8c 28860190 J. 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Genet. 2017 10.1007/s12041-016-0737-8 0 0 0 4 "Animals|*Muscle Development|*miRNAs|*Geese|Phylogeny|Gene Expression Profiling|RNA, Messenger|3' UTR|High-Throughput Nucleotide Sequencing|Muscle, Skeletal|Binding Sites|Gene Expression Regulation, Developmental|Cell Differentiation|Nucleic Acid Conformation|Muscle Proteins" 13 wdr73 28720660 Mol. Biol. Cell 2017 PMC5597322 10.1091/mbc.E17-01-0022 5 16 0 96 "Humans|*Arp2-3 Complex|*Amish|phosphatidylinositol 3-phosphate|Galloway Mowat syndrome|Nephrosis|Microcephaly|Hernia, Hiatal|Homozygote|Microtubule-Associated Proteins|Nephrotic Syndrome|Membrane Proteins|Mutations|Pedigree|Models, Molecular|Phenotype|WHAMM protein, human" 13 wdr73 28280135 J. Med. Genet. 2017 10.1136/jmedgenet-2016-104237 17 0 0 96 "Galloway Mowat syndrome|Nephrosis|*Homozygote|Microcephaly|*Mutation|Hernia, Hiatal|Nephrotic Syndrome|Phenotype|Brain" 13 ZNF385B 28600059 Taiwan J Obstet Gynecol 2017 10.1016/j.tjog.2017.04.026 0 0 0 17 "Pregnancy|Female|Humans|*Nuchal Translucency Measurement|Amniocentesis|Prenatal Diagnosis|*Syndactyly|Comparative Genomic Hybridization|Chromosome Deletion|Abnormalities, Multiple|*Chromosome Structures|*Transcription Factors|HOXD13 protein, human|Homeodomain Proteins|ZNF804A protein, human|Kruppel-Like Transcription Factors" 13 ZNF385B 28484033 Proc. Natl. Acad. Sci. 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Med. 2016 10.3892/ijmm.2016.2613 13 0 0 0 "Animals|Mice|*HMGB1 Protein|*RNA, Micro|*Lipopolysaccharides|*BALB C Mice|*Sepsis|RAW 264.7 Cells|Tumor Necrosis Factor-alpha|Upregulation|Anti-Inflammatory Agents|3-(2,4-dimethoxybenzylidene)anabaseine|Benzylidene Compounds|Downregulation|Signal Transduction|Cytokines|Pyridines" 13 MIR193B 27176876 Mol Med Rep 2016 10.3892/mmr.2016.5225 5 1 0 0 "Humans|*Barrett Esophagus|Adenocarcinoma Of Esophagus|*Esophageal Cancer|*Adenocarcinoma|DNA Methylation|Precancerous Conditions|Esophagus|Promoter Regions, Genetic|Immunohistochemistry|Biomarkers, Tumor|Cell Transformation, Neoplastic|RNA, Messenger|Disease Progression|MicroRNAs" 13 RASL11B 26851501 Neurobiol. Dis. 2016 10.1016/j.nbd.2016.02.004 6 1 0 35 "Mice|Animals|*Huntington Disease|histone H3 trimethyl Lys4|*Histones|Epigenesis, Genetic|Huntingtin Protein|Acetylation|*Promoter Regions, Genetic|Transcription, Genetic|Disease Models, Animal|Nerve Tissue Proteins|Protein Processing, Post-Translational" 13 REG1P 27846243 PLoS ONE 2016 PMC5112903 10.1371/journal.pone.0166282 9 3 0 0 "Humans|*Colorectal Cancer|Instability, Microsatellite|Fusobacterium|CpG Island|Colon|Bacteroides fragilis|DNA Methylation|Biomarkers, Tumor|*Colonic Neoplasms|Cell Transformation, Neoplastic|*Genomics|Tumorigenesis|Intestinal Mucosa|E coli, Enteropathogenic|REG1A protein, human|Lithostathine" 13 SFTA2 27221591 Ann. Anat. 2016 10.1016/j.aanat.2016.05.006 0 0 0 275 Humans|*Escherichia coli|SP-A Protein|Recombinant Proteins|Pulmonary Surfactants|Lung|Surface-Active Agents 13 SRBD1 27681326 Vet. Pathol. 2016 10.1177/0300985816666611 3 0 0 43 13 SRRD 27351204 Elife 2016 PMC4924995 10.7554/eLife.17290 36 11 1 66 "*Sequestosome-1 Protein|*Clustered Regularly Interspaced Short Palindromic Repeats|Adaptor Proteins, Signal Transducing|Signal Transduction|Autophagy|TOR Serine-Threonine Kinases|Protein Processing, Post-Translational|Protein Binding|Cells, Cultured" 13 TENM1 28004221 Clin. Exp. Med. 2016 10.1007/s10238-016-0445-y 9 0 0 81 "*Thyroid Cancer, Papillary|Thyroid Neoplasms|Iodine Radioisotopes|Carcinoma, Papillary|Proto-Oncogene Proteins B-raf|Carcinoma|*Disease Progression|Thyroid Gland|Lymphatic Metastasis|Prognosis|Immunohistochemistry|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Mutation|Downregulation" 13 TENM1 27905513 Sci Rep 2016 PMC5131482 10.1038/srep38096 17 1 0 81 "Pregnancy|Female|Animals|*Litter Size|*Polymorphism, Single Nucleotide|*Genome|*Goats|*Phenotype|Genotype|Fecundity|Selection, Genetic|Genes, cdc|China" 13 TENM1 27641332 Oncogene 2016 10.1038/onc.2016.341 14 3 0 81 "Humans|Mice|Animals|*Glioblastoma|RHOA protein, human|*rhoA GTP-Binding Protein|*Up-Regulation|Brain Neoplasms|Neoplastic Stem Cells|*Transcriptional Activation|Gene Expression Regulation, Neoplastic|Downregulation|Cell Differentiation|Cell Line, Tumor|Cell Proliferation|Cell Movement|Signal Transduction|Xenograft|RNA, Small Interfering" 13 TENM1 27040985 Clin. Genet. 2016 10.1111/cge.12782 21 0 0 81 "Mice|Animals|Congenital anosmia|*Olfaction Disorders|Drosophila melanogaster|Olfaction|Sensory Neurons, Olfactory|*Mutations|Pedigree|Odors|Sequencing, Whole Exome|Axons|Disease Models, Animal" 13 TENM1 26896429 Reprod. Biomed. 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Cell Proteomics 2015 PMC4424407 10.1074/mcp.M114.046698 8 6 1 29 "Humans|*Signal Transduction|Plasma Membrane|Adaptor Proteins, Signal Transducing|Nerve Tissue Proteins|Protein Transport|Receptor, NK-2|Green Fluorescent Proteins|Protein Binding|*Biological Assay|CLIC4 protein, human|Channel, Chloride|Protein Interaction Domains and Motifs|HEK293 Cells|G-Protein-Coupled Receptors|HeLa Cells|CLIC2 protein, human|BAIAP3 protein, human" 13 BCL7C 25569233 PLoS Genet. 2015 PMC4287490 10.1371/journal.pgen.1004921 9 26 2 77 "Humans|Animals|*Wnt Signaling Pathway|Caenorhabditis elegans|*Transcription Factors|*Genes, Tumor Suppressor|Caenorhabditis elegans Proteins|Wnt Proteins|Cell Differentiation|Stem Cells|Williams-Beuren Syndrome|Phenotype|Cells, Epithelial|BCL7A protein, human|Microfilament Proteins|Oncogene Proteins" 13 CCDC3 26614431 Tumour Biol. 2015 10.1007/s13277-015-4448-1 2 0 0 49 "*Tobacco|*Oral Cancers|Single Nucleotide Polymorphisms|Tobacco, Smokeless|Gene Frequency|Genotypes|Genetic Predisposition to Disease|Odds Ratio|Alleles|Carcinoma, Squamous Cell|Case-Control Studies|Tobacco Uses|India|*Risk" 13 CCDC3 25605713 J. 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Chem. 2015 PMC4367254 10.1074/jbc.M114.592493 3 2 0 49 "Mice|Rats|Animals|3T3-L1|Adipocytes|Adipogenesis|Adipose Tissue|Lipid Metabolism|Obesity|Cell Differentiation|Lipogenesis|Adipose Tissue, White|TYRP1 protein, human|*Membrane Glycoproteins|mRNA|Acetyl-CoA Carboxylase|Fatty Liver|Lipids" 13 CNTNAP3 25883416 Mediators Inflamm. 2015 PMC4391322 10.1155/2015/404185 2 13 0 49 "Humans|*Crohn Disease|Autophagy-Related Proteins|Nod2 Signaling Adaptor Protein|Autophagy|Carrier Proteins|Genetic Predisposition to Disease|Gene Expression|*Genes, Regulator|Case-Control Studies|CNTNAP3 protein, human|Membrane Proteins|Nerve Tissue Proteins|ATG16L1 protein, human" 13 CPAMD8 26537429 Sci Rep 2015 PMC4633681 10.1038/srep16264 5 2 1 5 "Animals|*Quantitative Trait Loci|*Genome-Wide Association Study|*Circadian Rhythm|Period Circadian Proteins|SNPs|*Hypothalamus|*Genes, Regulator|Phenotype|*Adaptation, Psychological" 13 DMRTA1 26138486 Nucleic Acids Res. 2015 PMC4538810 10.1093/nar/gkv589 36 29 2 70 "Mice|Animals|*Gene Regulatory Networks|Paired Box Transcription Factors|Transcription Factor PAX6|Homeodomain Proteins|*Prosencephalon|Eye Proteins|Repressor Proteins|Lens, Crystalline|histone H3 trimethyl Lys4|Histones|Chromatin|Gene Expression Regulation, Developmental|Cell Differentiation|Binding Sites|*Organogenesis|Protein Binding|DNA|Pax6 protein, mouse" 13 DNAH10 26517670 Acta Neurol. Scand. 2015 PMC5057358 10.1111/ane.12515 4 8 1 8 "*Charcot-Marie-Tooth Disease|Norway|Sequencing, Next-Generation|Genetic Testing|Pedigree|Mutation|*Genes, Regulator" 13 DNAH10 26420031 Eur J Med Genet 2015 10.1016/j.ejmg.2015.09.010 0 0 0 8 "Humans|*Exome|Hand Deformities, Congenital|Pierre Robin Syndrome|*Whole Exome Sequencing|Abnormalities, Multiple|Homozygote|Mutations|Phenotype|Fingers" 13 DNAH10 26061684 Int. J. Cancer 2015 PMC4755138 10.1002/ijc.29630 7 3 0 8 "Humans|*Carcinoma, Renal Cell|*CpG Islands|Kidney Neoplasms|DNA Methylation|*Phenotype|Exome|Mutation|Genes, cdc|NEK2 protein, human|NIMA-Related Kinases" 13 DNAJB12 26367535 PLoS ONE 2015 PMC4569262 10.1371/journal.pone.0136989 4 1 1 28 "*Acquired Immunodeficiency Syndrome|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Disease Progression|Cohort Studies" 13 DNAJB5 26713440 PLoS ONE 2015 PMC4700982 10.1371/journal.pone.0145801 6 1 1 67 "Animals|Male|*Zebrafish|*Transcriptome|*Brain|Social Behavior|Behavior, Animal|Aggression|Learning|Oligonucleotide Array Sequence Analysis|Attention" 13 DNAJB5 26257172 Cell Rep 2015 PMC4545408 10.1016/j.celrep.2015.07.023 82 2 5 67 "Humans|*Exome|Charcot Marie Tooth Disease|*Genetic Testing|Myelin P2 Protein|Phenotype|Sequencing, Whole Exome|Mutation|Pedigree|*Phenotypic Variability" 13 EMC10 26512320 F1000Res 2015 PMC4602282 10.12688/f1000research.6944.2 24 0 1 130 Animals|*Endoplasmic Reticulum|Mitochondrial Membranes|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Mitochondria|Membrane Proteins|Biological Transport 13 EMC10 25849460 J. 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Evol. 2015 PMC4662009 10.1186/s12711-015-0173-x 18 1 2 26 "Cattle|Animals|South Africa|*Breeding|Selection, Genetic|Genotype|Gene Frequency|Haplotypes|Quantitative Trait Loci|Phenotype|Polymorphism, Single Nucleotide|Genomics" 13 HSPB9 25685801 Biomed Res Int 2015 PMC4317599 10.1155/2015/686239 1 0 0 26 "Male|Animals|*Testis|*Heat-Shock Proteins, Small|*Goat|*Spermatogenesis|*Stress, Heat|Spermatocytes|Spermatids|Spermatogonia|*Heat Stress Disorders|Heat-Shock Proteins|HSP70 Heat-Shock Proteins|RNA, Messenger|Hot Temperature" 13 HYAL4 26588071 PLoS Genet. 2015 PMC4654484 10.1371/journal.pgen.1005647 13 4 1 7 "Humans|Dogs|Animals|*Genome-Wide Association Study|*Risk Factors|Dog Diseases|*Mast Cells|Mastocytoma|Oncogenes|Haplotypes|Genetic Predisposition to Disease|Mutations|Proto-Oncogene Proteins c-kit|*Germ Line|Skin Neoplasms|*Myeloproliferative Disorders|hyaluronidase PH-20|Cell Adhesion Molecules|Breeding|Hyaluronidase|Hyal2 protein, human" 13 ITPRIP 26537080 J BUON 2015 1 0 0 920 "Humans|*Bortezomib|*Multiple Myeloma|Boronic Acids|Pyrazines|Antineoplastic Agents|*B-Lymphocytes|Prognosis|BIRC5 protein, human|Survivin|*Gene Expression" 13 ITPRIP 26196352 Crit. Care Med. 2015 10.1097/CCM.0000000000001204 9 2 1 920 "Humans|Out-of-Hospital Cardiac Arrest|Cardiopulmonary Resuscitation|Hypothermia, Induced|Hospital Mortality|Intensive Care Units|*Alarmins|Cytokines|Risk Assessment" 13 LAMB4 26215952 J. Clin. Oncol. 2015 10.1200/JCO.2015.62.0674 55 0 3 2 "Carcinoma, Non-Small-Cell Lung|Crizotinib|Proto-Oncogene Proteins c-met|Lung Neoplasms|*Sequencing, Next-Generation|Exons|Protein Kinase Inhibitors|Adenocarcinoma|Mutation|*Carcinoma|Pyrazoles|Pyridines" 13 LAMB4 26179511 Clin. Cancer Res. 2015 10.1158/1078-0432.CCR-14-2744 17 1 6 2 "Humans|Child|*Sarcoma, Ewing|*Neuroectodermal Tumors, Primitive, Peripheral|RNA-Binding Protein EWS|Proteins, Oncogene Chimeric|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|Cell Line, Tumor|Mutation|Mutation Rate|High-Throughput Nucleotide Sequencing" 13 LAMB4 26136121 J. Periodontol. 2015 10.1902/jop.2015.150175 1 0 0 2 Humans|*Aggressive Periodontitis|*Gene Regulatory Networks|*Gene Expression Profiles|Gingiva|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Computational Biology|Up-Regulation 13 LIMCH1 26678503 Histochem. Cell Biol. 2015 10.1007/s00418-015-1389-0 2 0 0 160 "Animals|Rats|agmatinase|Escherichia coli|Ureohydrolases|Agmatine|*Isoforms|Amino Acid Sequence|Brain|Neurotransmitter|Hypothalamus|arginine decarboxylase|Carboxy-Lyases|Kinetics|Hippocampus|Cloning, Molecular" 13 MIR193B 26573160 Mol Med Rep 2015 PMC4686085 10.3892/mmr.2015.4556 8 3 1 0 "Humans|Female|*Carcinoma, Ovarian Epithelial|*Neuropilin-1|*Gene Regulatory Networks|*Ovarian Neoplasms|Neoplasms, Glandular and Epithelial|*Multidrug Resistance|MicroRNAs|Gene Expression Regulation, Neoplastic|Upregulation|Cell Line, Tumor|Drug Resistance, Neoplasm|Signal Transduction|MIRN141 microRNA, human" 13 PRSS35 26602496 J Craniomaxillofac Surg 2015 10.1016/j.jcms.2015.07.026 9 0 0 22 "Orofacial Cleft 1|*Cleft Lip|*Cleft Palate|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Interferon Regulatory Factors|Alleles|Genotype|*Brain|Case-Control Studies|Palate|Brazil" 13 PRSS35 26276571 Reprod. Biol. Endocrinol. 2015 PMC4537566 10.1186/s12958-015-0091-3 9 0 1 22 "Pregnancy|Female|Humans|*Serpin E2|*Oogenesis|Cumulus Cells|*Embryo Development|Oocyte|Serum Amyloid P-Component|*Gene Expression|Sperm Injections, Intracytoplasmic|Ovary|RNA, Messenger|C-Reactive Protein|SERPINE2 protein, human|GJA1 protein, human|Connexin 43|PRSS35 protein, human|Serine Proteases" 13 PRSS35 26602496 J Craniomaxillofac Surg 2015 10.1016/j.jcms.2015.07.026 9 0 0 22 "Orofacial Cleft 1|*Cleft Lip|*Cleft Palate|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Interferon Regulatory Factors|Alleles|Genotype|*Brain|Case-Control Studies|Palate|Brazil" 13 PRSS35 26276571 Reprod. Biol. Endocrinol. 2015 PMC4537566 10.1186/s12958-015-0091-3 9 0 1 22 "Pregnancy|Female|Humans|*Serpin E2|*Oogenesis|Cumulus Cells|*Embryo Development|Oocyte|Serum Amyloid P-Component|*Gene Expression|Sperm Injections, Intracytoplasmic|Ovary|RNA, Messenger|C-Reactive Protein|SERPINE2 protein, human|GJA1 protein, human|Connexin 43|PRSS35 protein, human|Serine Proteases" 13 RASL11B 26028028 Oncogene 2015 10.1038/onc.2015.144 3 4 2 35 "Humans|*Binding Proteins|Glycogen Synthase Kinase 3|*Cell Death|Lactalbumin|Oleic Acids|Antineoplastic Agents|Cell Line, Tumor|Apoptosis|Cell Survival|Protein Kinase Inhibitors|Oncogenes|*Nucleotides|Models, Molecular|Lung Neoplasms" 13 TBX10 26602496 J Craniomaxillofac Surg 2015 10.1016/j.jcms.2015.07.026 9 0 0 6 "Orofacial Cleft 1|*Cleft Lip|*Cleft Palate|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Interferon Regulatory Factors|Alleles|Genotype|*Brain|Case-Control Studies|Palate|Brazil" 13 TBX10 25893793 Hum. Genet. 2015 10.1007/s00439-015-1549-2 6 0 1 6 "Humans|Indonesia|*Osteochondrodysplasias|*Musculoskeletal Abnormalities|Phenotype|Homozygote|Dwarfism|Dysplasia, Bone|galactosylgalactoylxylosylprotein 3-beta-glucuronosyltransferase|Glucuronyltransferase|Mutation|Pedigree|Mutation, Missense|*Islands|Genetic Linkage|B3GAT3 protein, human" 13 TENM1 25666757 Mol. Psychiatry 2015 10.1038/mp.2014.189 30 0 3 81 "*Whole Exome Sequencing|*Genetic Heterogeneity|*Cerebral Palsy|Exome|Mutation|Genetic Predisposition to Disease|Sequence Analysis, DNA|Protein-Serine-Threonine Kinases" 13 TENM1 25648896 J. Biol. Chem. 2015 PMC4375472 10.1074/jbc.M114.615922 9 4 0 81 "Humans|MITF protein, human|*Microphthalmia-Associated Transcription Factor|teneurin-1|*Nerve Tissue Proteins|*Tenascin|Transcriptional Activation|Promoter Regions, Genetic|Protein Binding|*Cytoplasm|Up-Regulation|Membrane Proteins|Signal Transduction|Cell Nucleus|HINT1 protein, human|GPNMB protein, human|Membrane Glycoproteins|Ten1 protein, human|Telomere-Binding Proteins" 13 TFDP3 26362298 Comput Biol Chem 2015 10.1016/j.compbiolchem.2015.08.007 14 0 0 176 "*Gene Regulatory Networks|Transcription Factors|Computational Biology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Algorithms|Phenotypes|Cancer" 13 wdr73 26123727 Hum. 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Signal. 2014 10.1016/j.cellsig.2014.08.025 7 25 2 49 "Endothelial Cells|*Complement Factor B|Vascular Cell Adhesion Molecule 1|Tumor Necrosis Factor-alpha|*Inflammation|Intercellular Adhesion Molecule-1|NF-kappa B|E-Selectin|Cell Adhesion|*Cell Nucleus|Endothelium, Vascular|Cells, Cultured|*Transcription Factors" 13 cmtr1 24402442 Nat Commun 2014 PMC3941023 10.1038/ncomms4004 22 6 1 62 "Humans|*Methylation|*Ribose|RNA Caps|methylcobalamin-coenzyme M methyltransferase|*Methyltransferases|*RNA Processing, Post-Transcriptional|Messenger RNA|*Archaeal Proteins|RNA, Viral|Binding Sites|Models, Molecular" 13 CNTNAP3 25522406 Int. J. Neuropsychopharmacol. 2014 PMC4360232 10.1093/ijnp/pyu066 0 0 0 49 *Antipsychotic Agents|*Transcriptome|Genome-Wide Association Study|*Schizophrenia|Risperidone|Olanzapine|Quetiapine Fumarate|Dibenzothiazepines|Aripiprazole|Clozapine|Benzodiazepines|Schizophrenic Psychology|Piperazines|Quinolones|Psychiatric Status Rating Scales|Thiazoles|Treatment Outcome 13 CNTNAP3 25424124 Orphanet J Rare Dis 2014 PMC4254261 10.1186/s13023-014-0181-x 2 0 1 49 "Middle Aged|Humans|Male|Testicular Germ Cell Tumor|*Twins, Monozygotic|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Phenotype|Genomics" 13 CNTNAP3 25102227 Mol. Cell. Endocrinol. 2014 10.1016/j.mce.2014.07.011 0 0 0 49 "Humans|Adipocytes, White|Adipocytes, Brown|*Progenitor Cells|*Adipose Tissue, Subcutaneous|Adipogenesis|Cell Differentiation|Adipose Tissue|Genes, cdc|ADH1B protein, human|Alcohol Dehydrogenase" 13 DMRTA1 25218607 Support Care Cancer 2014 PMC4371856 10.1007/s00520-014-2406-x 4 2 0 70 "*Multiple Myeloma|*Genome-Wide Association Study|*Oral Mucositis|Melphalan|*Mucositis|Transplantation, Autologous|Transplantation Conditioning|Hematopoietic Stem Cell Transplantation|*Induction Chemotherapy|Risk Factors|Antineoplastic Agents|*Stem Cell" 13 DNAH10 24891332 J. Lipid Res. 2014 PMC4109763 10.1194/jlr.M048710 8 0 2 8 "Humans|*Cholesterol, HDL|CETP protein, human|Cholesteryl Ester Transfer Protein|APOA1 protein, human|ApoA-I|*Cholesterol, Elevated|Phosphatidylcholine-Sterol O-Acyltransferase|ATP Binding Cassette Transporter 1|Mutations|Genotype|LIPG protein, human|Lipase|Scavenger Receptors, Class B|Phenotype|ATP-Binding Cassette Transporters|Genetic Predisposition to Disease|polypeptide N-acetylgalactosaminyltransferase|N-Acetylgalactosaminyltransferases" 13 DNAJB12 24732912 PLoS ONE 2014 PMC3986390 10.1371/journal.pone.0094322 7 14 1 28 "*Nuclear Pore|Nuclear Envelope|Endoplasmic Reticulum|*Cell Nuclei|HSP40 Heat-Shock Proteins|Molecular Chaperones|HSC70 Heat-Shock Proteins|Protein Folding|Membrane Proteins|Protein Transport|*Membranes|Heat-Shock Proteins, HSP70" 13 DNAJB12 24675744 PLoS Pathog. 2014 PMC3968126 10.1371/journal.ppat.1004007 37 39 7 28 "Humans|*Cytosol|*Membrane Proteins|*Endoplasmic Reticulum|*Molecular Chaperones|Simian virus 40|Intracellular Membranes|Polyomavirus Infections|Biological Transport|Gene Knockdown Techniques|RNA, Small Interfering|Virus Internalization|HEK293 Cells|DNAJB12 protein, human|HSP40 Heat-Shock Proteins" 13 DSTYK 25400726 Int J Clin Exp Pathol 2014 PMC4230056 3 0 0 199 "Mice|Animals|*Maze Learning|*Memory|Mice, Knockout|Memory Disorders|Learning Disabilities|Mice, Inbred C57BL|Behavior, Animal|Anxiety|Motor Activity|Brain" 13 EMC10 25481245 BMC Cancer 2014 PMC4295481 10.1186/1471-2407-14-920 1 27 0 130 "Humans|Endothelial Cells|*Glioma|Glioblastoma|*Neovascularization, Pathologic|Brain Neoplasms|peptide B|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Movement|Cell Line, Tumor|Apoptosis|*Hematopoietic System|Proteins|Protein Sorting Signals|Hematopoietic Stem Cell Transplantation" 13 FOCAD 25219767 Int. J. Cancer 2014 10.1002/ijc.29215 17 0 4 27 "Humans|*Adenomatous Polyposis Coli|*Sequencing, Next-Generation|Colorectal Cancer|DNA Glycosylases|Mutations|Genetic Testing|Sequence Analysis, DNA|Germ-Line Mutation|Genetic Predisposition to Disease|DNA Copy Number Variations|Adenoma|CTNNB1 protein, human|beta Catenin|Cohort Studies|FOCAD protein, human|Tumor Suppressor Proteins" 13 GLT8D1 24373612 J Psychiatr Res 2014 10.1016/j.jpsychires.2013.12.002 5 0 0 18 "Humans|Depressive Disorder, Major|Asian|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Schizophrenia|Genotype|Genome-Wide Association Study|Linkage Disequilibrium|Gene Frequency|Allele|Case-Control Studies|European Continental Ancestry Group|GLT8D1 protein, human|Glycosyltransferases" 13 GSX1 25224259 Mol. Psychiatry 2014 PMC4362800 10.1038/mp.2014.106 15 3 1 108 "Animals|Mice|*Prepulse Inhibition|Startle Response|*Neurons|Acoustic Stimulation|Optogenetic|Auditory Perception|Zebrafish|Brainstem|Larvae|Brain|Mice, Knockout" 13 GSX1 24535035 Nat Commun 2014 PMC5669625 10.1038/ncomms4337 19 13 4 108 "*Purkinje Cells|*Cerebellum|*Interneuron|OLIG2 protein, human|Oligodendrocyte Transcription Factor 2|GABAergic Neurons|Cell Lineage|Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|Transcription Factors|Stem Cells|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|PAX2 Transcription Factor|gamma-Aminobutyric Acid" 13 HSPB9 25352652 Hum Exp Toxicol 2014 10.1177/0960327114555927 5 0 1 26 "Pregnancy|Female|Mice|Animals|*Heat Shock Proteins|glucose-regulated proteins|HSP70 Heat-Shock Proteins|DNAJB1 protein, human|HSP40 Heat-Shock Proteins|*Teratogenesis|*Hindlimbs|Tretinoin|Forelimb|TRAP1 protein, human|HSP90 Heat-Shock Proteins|Embryonic Development|Gene Expression Regulation, Developmental|*Gene Expression|Chaperonin 60|RNA, Messenger|Abnormalities, Drug-Induced|Membrane Proteins" 13 HYAL4 24668563 Cancer 2014 PMC4047165 10.1002/cncr.28646 13 26 1 7 "Humans|Male|hyaluronan-mediated motility receptor|*Hyaluronic Acid|CD44 protein, human|*Hyaluronan Receptors|*Extracellular Matrix Proteins|*Prostate Cancer|hyaluronidase PH-20|Hyaluronidase|Prostatectomy|Cell Movement|Cell Adhesion Molecules|Tumor Microenvironment" 13 IQSEC3 24613754 Gene 2014 10.1016/j.gene.2014.02.058 4 0 3 41 "Child|Humans|Chromosome 12p partial deletion|Chromosome 12p deletion|*Chromosome Deletion|*Autism Spectrum Disorder|*Chromosomes, Human, Pair 12|Genetic Association Studies|Developmental Disabilities|Phenotype|Comparative Genomic Hybridization|Child Development Disorders, Pervasive|Language Development Disorders|Nerve Tissue Proteins|In Situ Hybridization, Fluorescence|NINJ2 protein, human|Cell Adhesion Molecules, Neuronal|FBXL14 protein, human|Ubiquitin-Protein Ligases|F-Box Proteins" 13 ITPRIP 25464930 J. Mol. Neurosci. 2014 10.1007/s12031-014-0470-9 6 0 0 920 "Humans|neuroligin 3|*Autistic Disorder|*Cell Adhesion Molecules, Neuronal|*Nerve Tissue Proteins|Membrane Proteins|Neurons|Genetic Predisposition|Neuroblastoma|EEF1A1 protein, human|Peptide Elongation Factor 1|Gpr175 protein, human|ACOT2 protein, human|Thiolester Hydrolases" 13 ITPRIP 24684592 Scand. J. Immunol. 2014 PMC4282429 10.1111/sji.12175 15 18 1 920 Th2 Cells|Th1 Cells|Interleukin-4|Antigen|CD4-Positive T-Lymphocytes|Interferon-gamma|Immunization|Mycobacterium tuberculosis|HIV-1|*Phenotype|Vaccination 13 LAMB4 25257191 APMIS 2014 10.1111/apm.12309 5 0 0 2 "*Laminin|Instability, Microsatellite|*Colorectal Cancers|Mutations, Frameshift|DNA, Neoplasm|*Stomach|Stomach Neoplasms|Polymorphism, Single-Stranded Conformational|Immunohistochemistry|Mutation|Base Sequence|Polymerase Chain Reaction|DNA Sequencing|Exons|laminine|*Amino Acids, Diamino" 13 LAMB4 24866589 Med. Sci. Monit. 2014 PMC4049949 10.12659/MSM.890031 5 7 3 2 "Humans|*Ranibizumab|Angiogenesis Inhibitors|Visual Acuity|Vascular Endothelial Growth Factor A|Wet Macular Degeneration|Choroidal Neovascularization|Intravitreal Injections|Antibodies, Monoclonal, Humanized|Fluorescein Angiography|Antibodies, Monoclonal|Tomography, Optical Coherence|Vitreous Body|Treatment Outcome|*Extracellular Matrix" 13 LIMCH1 24479813 BMC Urol 2014 PMC3944917 10.1186/1471-2490-14-14 10 0 0 160 "*Carcinoma, Renal Cell|Kidney Neoplasms|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|*Tobacco Smoking|*Smoking" 13 MIR193B 25215905 Mol Med Rep 2014 10.3892/mmr.2014.2558 20 2 7 0 "*Urokinase-Type Plasminogen Activator|*Pancreatic Cancer|MicroRNAs|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|PLAU protein, human|*Membrane Proteins|Cell Proliferation|*Neoplastic Processes|3' Untranslated Regions|Cell Line, Tumor|Down-Regulation|Cell Movement|Apoptosis|*Genes, Regulator|Cell Transformation, Neoplastic" 13 MIR193B 25119742 Mol Med Rep 2014 10.3892/mmr.2014.2484 28 2 3 0 "Humans|Mice|Animals|*Amyloid beta-Protein Precursor|*Alzheimer Disease|Amyloid beta-Peptides|tau Proteins|*Biomarkers|Cognitive Impairment, Mild|Peptide Fragments|Hippocampus|RNA, Micro|Cognition Disorders|3' Untranslated Region|Binding Sites|Downregulation|mRNA" 13 RASL11B 24722050 PLoS ONE 2014 PMC3983164 10.1371/journal.pone.0094390 8 12 1 35 "Humans|Infant, Newborn|Mice|Animals|Alveolar capillary dysplasia|*Persistent Fetal Circulation Syndrome|*Mice, Knockout|*Transcriptome|*Pulmonary Alveoli|*Lung|*Pulmonary Veins|*Heterozygote|Forkhead Transcription Factors|Sequence Deletion|Mutation|Hypertension, Pulmonary|Comparative Genomic Hybridization|FOXF1 protein, human|FSCN1 protein, human|Carrier Proteins|Microfilament Proteins|PRKCDBP protein, human" 13 RILPL2 25230296 Acc. Chem. Res. 2014 10.1021/ar500216z 12 0 3 24 "Humans|*Myosins|myosin VI|Myosin Heavy Chains|MYO5A protein, human|Myosin V|Filaments, Actin|Amino Acid Sequence|Organelles|Models, Molecular|Cytoskeleton|Kinesin|Protein Transport|Microtubules|VIIa, Myosin|Biological Transport|Dimerization" 13 SFTA2 25404243 Liver Int. 2014 10.1111/liv.12740 5 0 0 275 "Humans|*Hepatitis B, Chronic|Genome-Wide Association Study|Republic of Korea|Hepatitis B virus|Asian|Hepatocellular Carcinoma|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Liver Neoplasms|Haplotypes|Liver Cirrhosis|Case-Control Studies|Hepatitis B Virus Infection|Genetic Loci|Risk Factor|Odds Ratio|VARS2 protein, human|HLA Antigens" 13 SRBD1 25461262 Am. J. Ophthalmol. 2014 10.1016/j.ajo.2014.11.023 9 0 0 43 "*Glaucoma, Primary Open Angle|Normal Tension Glaucoma|Intraocular Pressure|Tonometry, Ocular|*Glaucoma|Genotype|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|*Tetrahymenina" 13 SRBD1 25414181 Invest. Ophthalmol. Vis. Sci. 2014 PMC4271633 10.1167/iovs.14-15712 9 0 2 43 "*DNA Copy Number Variations|*Glaucoma, Primary Open Angle|Genetic Predisposition to Disease|Gene Frequency|*Glaucoma|Polymorphism, Single Nucleotide|Intraocular Pressure|Alleles|Genotype|Genetic Variation|Case-Control Studies|Homeodomain Proteins" 13 TENM1 24736764 Mol Med Rep 2014 10.3892/mmr.2014.2152 9 0 1 81 "*Prolactin|*Pituitary Neoplasms|Gene Ontology|Gene Regulatory Networks|Bioinformatics|Gene Expression Profiling|Databases, Genetic|Cluster Analysis|Profile, Gene Expression|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Microarray Analysis|Downregulation|Upregulation" 13 TFDP3 24406621 Gene 2014 10.1016/j.gene.2013.12.051 10 3 1 176 "Humans|Male|*Apoptosis|Transcription Factor DP1|E2F1 Transcription Factor|*Prostate Cancer|Liver Cancer|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|Prostate|Liver|Cell Survival|E2F1 protein, human|TFDP3 protein, human" 13 tmem8c 25078621 Biochem. Biophys. Res. Commun. 2014 10.1016/j.bbrc.2014.07.093 18 0 2 4 "Mice|Animals|*Zebrafish|Zebrafish Proteins|Muscle Development|Myotubes|Muscle Proteins|Cell Fusion|Membrane Proteins|Swimming|Phenotype|myomaker protein, mouse|myomaker protein, zebrafish" 13 wdr73 25466283 Am. J. Hum. Genet. 2014 PMC4259970 10.1016/j.ajhg.2014.10.011 31 2 2 96 "Child|Humans|Galloway Mowat syndrome|*Microcephaly|*Nephrotic Syndrome|*Nephrosis|*Hernia, Hiatal|*Mutations|Homozygote|Kidney|Proteins|Brain|Pedigree|Phenotype|Kidney Glomerulus|WDR73 protein, human" 13 ZNF385B 24599690 J Zhejiang Univ Sci B 2014 PMC3955913 10.1631/jzus.B1300133 7 1 1 17 "Humans|*Autistic Disorder|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Association Studies|Linkage Disequilibrium|*Family Relations|Genotype|Nerve Tissue Proteins|IMMP2L protein, human|Endopeptidases|DOCK4 protein, human|GTPase-Activating Proteins" 13 BAIAP3 23698091 Mol. Med. 2013 PMC3745598 10.2119/molmed.2013.00033 7 0 0 29 "Male|Female|Mice|Animals|Humans|*Genetic Markers|Diazepam|Seizure|*Anxiety|Benzodiazepines|Anti-Anxiety Agents|Pentylenetetrazole|*Substance Abuse|Substance Withdrawal Syndrome|*Anxiety Disorders|Baiap3 protein, mouse|Nerve Tissue Proteins|*Psychotropic Drugs|BAIAP3 protein, human" 13 BCL7C 23644491 Nat. Genet. 2013 PMC3667980 10.1038/ng.2628 330 10 32 77 "Animals|Humans|*Computational Biology|*Proteomics|Transcription Factors|*Malignancy|Chromosomal Proteins, Non-Histone|Chromatin Assembly and Disassembly|Chromatin|Mutation|*Mammals|Exome|Mutation Frequency|BCL7A protein, human|Microfilament Proteins|Oncogene Proteins|BRD9 protein, human" 13 BTBD10 24156551 BMC Biochem. 2013 PMC3827329 10.1186/1471-2091-14-27 2 37 0 44 *Proto-Oncogene Proteins c-akt|Protein Phosphatase 2A|Intracellular Signaling Peptides and Proteins|Phosphorylation|Nuclear Proteins|Signal Transduction|Cell Death|Cell Proliferation|Transfection|Protein Binding|Motor Neurons|Cell Line|Amino Acid Sequence 13 BTBD10 23564125 Acta Neurochir. Suppl. 2013 10.1007/978-3-7091-1434-6_30 0 4 0 44 "Rats|Animals|*Cerebral Hemorrhage|*Apoptosis|*Brain Injury|In Situ Nick-End Labeling|Proto-Oncogene Proteins c-akt|Rats, Sprague-Dawley|*Synapsins|Neurons|Brain Edema|Signal Transduction|Phosphorylations|Neuroprotective Agents|Caudate Nucleus|Disease Models, Animal" 13 BTBD10 23592240 Bioessays 2013 10.1002/bies.201300002 25 4 0 44 "Animals|ribosomal protein S6 kinase, 70kD, polypeptide 2|p70s6k|MTOR protein, human|TOR Serine-Threonine Kinases|Signal Transduction|Proto-Oncogene Proteins c-akt|TYRP1 protein, human|*Membrane Glycoproteins|Transcription Factors|Phosphorylation|*Vertebrate|CKAP5 protein, human|Microtubule-Associated Proteins|Cell Differentiation" 13 BTBD10 23330007 Int J Clin Exp Pathol 2013 PMC3544232 5 4 0 44 "Rats|Animals|*Proto-Oncogene Proteins c-akt|*Cerebral Hemorrhage|*Brain Injury|Apoptosis|Rats, Sprague-Dawley|Phosphorylation|Neurons|Signal Transduction|Neuroprotective Agents|Disease Models, Animal|Brain" 13 BTBD10 23320755 Neuropathology 2013 10.1111/neup.12010 3 2 0 44 Humans|*Anterior Horn Cells|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|*Inclusion Bodies|SOD1 G93A protein|Superoxide Dismutase|Motor Neuron|*Golgi Apparatus|Superoxide Dismutase-1|Spinal Cords|DNA-Binding Proteins|Phosphorylation|Mutation 13 CCDC141 23973799 Stem Cell Res 2013 10.1016/j.scr.2013.07.007 0 0 0 34 "Mice|Animals|*Mouse Embryonic Stem Cells|*Embryonic Stem Cells|POU5F1 protein, human|Octamer Transcription Factor-3|Cell Differentiation|Neural Stem Cells|Homeodomain Proteins|Embryoid Body|Paired Box Transcription Factors|Nanog Homeobox Protein|Cell Line|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Eye Proteins|PAX6 Transcription Factor|*B Cells|Cells, Cultured|CCDC141 protein, mouse" 13 CCDC3 24123834 Obesity (Silver Spring) 2013 10.1002/oby.20645 3 0 0 49 "*Obesity, Abdominal|*Obesity|*Adipose Tissue|Subcutaneous Fat|Body Mass Index|Adipocytes|Omentum|Blood Glucose|*Upregulation|Lipids|*Peritoneum" 13 CNTNAP3 23793063 J Perinat Med 2013 PMC4164302 10.1515/jpm-2013-0082 0 5 0 49 "Pregnancy|Humans|Female|*Pre-Eclampsia|Oligonucleotide Array Sequence Analysis|Placenta|*Phenotype|Gene Expression Profiling|*Databases, Genetic|Case-Control Studies" 13 DMRTA1 23679989 Genes Cells 2013 10.1111/gtc.12061 12 6 4 70 "Rats|Animals|*Telencephalon|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|ASCL1 protein, human|Paired Box Transcription Factors|Transcription Factor PAX6|Homeodomain Proteins|Eye Proteins|Repressor Proteins|Neurogenesis|Neural Stem Cells|Neurons|Nerve Tissue Proteins|Cell Differentiation|Cerebral Cortex|Gene Expression Regulation, Developmental|Ascl1 protein, rat|Pax6 protein, rat" 13 DMRTA1 23523356 Cell Rep 2013 PMC3648982 10.1016/j.celrep.2013.02.023 24 8 7 70 "Animals|*Neocortex|TCF12 protein, human|Basic Helix-Loop-Helix Transcription Factors|Neurogenesis|Neurons|Transcription Factor|Neural Stem Cells|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Homeodomain Proteins|Cell Differentiation" 13 DNAH10 23682429 Biocell 2013 5 0 0 8 Animals|*Trypanosoma brucei brucei|*Axoneme|*Dyneins|Flagellum|Protozoan Proteins|African Sleeping Sickness|RNAi|*Cilia|Amino Acid Sequence|Cell Movement|Life Cycle 13 DSTYK 23862974 N. Engl. J. Med. 2013 PMC3846391 10.1056/NEJMoa1214479 41 6 2 199 "Humans|Child|*Urinary Tract|*Mutations|Exome|Urogenital Abnormalities|Kidney|Pedigree|Phenotype|DSTYK protein, human|Receptor-Interacting Protein Serine-Threonine Kinases" 13 EMC10 23332760 Cell 2013 PMC3556818 10.1016/j.cell.2012.11.052 61 10 3 130 "Animals|Mice|*miRNA|Hippocampus|Neurons|Brain|Schizophrenia|Chromosome Deletion|Disease Models, Animal" 13 FNDC3A 23639254 Psychiatry Res 2013 10.1016/j.psychres.2013.02.028 0 1 0 117 "Child|Humans|*Single Nucleotide Polymorphism|*Autism Spectrum Disorder|Republic of Korea|Genetic Predisposition to Disease|Linkage Disequilibrium|Asian Continental Ancestry Group|Gene Frequency|Genotype|Child Development Disorders, Pervasive|Logistic Regression|Nucleotides|FNDC3A protein, human|Fibronectins" 13 GLT8D1 24114764 Cancer 2013 10.1002/cncr.28354 10 0 0 18 "Humans|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|*Epigenetic|Carcinoma, Squamous Cell|DNA Methylation|Epigenesis, Genetic|Forkhead Box Protein M1|Promoter Regions, Genetic|Biomarkers, Tumor|Forkhead Transcription Factors|Cell Line, Tumor|Oncogene|FOXM1 protein, human" 13 GSX1 23788430 J. Cell. Sci. 2013 PMC3744023 10.1242/jcs.125757 12 1 1 108 "Humans|Rats|Animals|*Fibroblast Growth Factor 2|BMP4 protein, human|*Bone Morphogenetic Protein 4|Neural Stem Cells|neuronectin|Nerve Tissue Proteins|Cell Differentiation|*Signal Transduction|NGFR protein, human|Neural Crest Cells|Neurons|*B Cells|Extracellular Matrix Proteins|Cells, Cultured|Upregulation|Receptors, Nerve Growth Factor" 13 HSPB9 23337768 Eur J Med Genet 2013 10.1016/j.ejmg.2012.12.005 0 0 0 26 "Child|Male|Humans|Microcephaly|*Musculoskeletal Abnormalities|Developmental Disabilities|Comparative Genomic Hybridization|Intellectual Disability|Abnormalities, Multiple|Gene Duplication|Face|*Chromosome Structures" 13 HYAL4 23451178 PLoS ONE 2013 PMC3579804 10.1371/journal.pone.0057168 13 0 2 7 Humans|DNA Copy Number Variations|*Glioma|Chromosome Aberrations|Nucleic Acid Hybridization|*Genomics|Neoplasm Grading|*Chinese 13 IQSEC3 23926013 Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2013 10.3760/cma.j.issn.1003-9406.2013.04.014 0 0 0 41 "Humans|Infant|*Cri-du-Chat Syndrome|*Comparative Genomic Hybridization|*DNA Copy Number Variations|Chromosome Banding|Chromosome Deletion|In Situ Hybridization, Fluorescence|Phenotype" 13 LAMB4 23585368 Hum. Mutat. 2013 10.1002/humu.22333 22 0 4 2 "Humans|Adult|*Exome|*Genes, Suppressor|*Colorectal Cancer|Mutations, Germline|Adenomatous Polyposis Coli|Adenomatous Polyposis Coli Protein|Genetic Predisposition to Disease|Alleles|*Genotype|Mutations|Pedigree|Polymorphism, Single Nucleotide|Sequence Analysis, DNA|*Colonic Neoplasms|TREX2 protein, human|Exodeoxyribonucleases|Phosphoproteins" 13 MIR193B 23588298 Int. J. Oncol. 2013 PMC3699598 10.3892/ijo.2013.1896 36 2 9 0 "Humans|Female|*Carcinoma, Ovarian Epithelial|*RNA, Micro|*Ovarian Cancer|Cell Line, Tumor|*Gain of Function Mutation|*Apoptosis|Neoplasms, Glandular and Epithelial|Cell Proliferation|CCND1 protein, human|Cyclin D1|Gene Expression Regulation, Neoplastic|MCL1 protein, human|Myeloid Cell Leukemia Sequence 1 Protein|Cell Movement|Down-Regulation|CASP3 protein, human|Caspase 3|3' Untranslated Regions" 13 PRSS35 23451081 PLoS ONE 2013 PMC3579851 10.1371/journal.pone.0056757 12 14 2 22 "Pregnancy|Female|Mice|Animals|*Serine Proteases|Embryo Implantation|Progesterone|Uterus|*Serine Endopeptidases|Oestradiol|*Fertility|Corpus Luteum|Embryo Development|Blotting, Northern|Estrogens|Ovary|RNA, Messenger|Gene Expression|Superovulation|PRSS23 protein, mouse" 13 PRSS35 23437119 PLoS ONE 2013 PMC3577807 10.1371/journal.pone.0056376 10 12 3 22 "Female|Humans|Mice|Animals|*Protease Inhibitors|*Pelvic Organ Prolapse|Vagina|Uterine Prolapse|Matrix Metalloproteinase 9|Elastic Fibers|Extracellular Matrix Proteins|*Endopeptidases|Proteases|*Disease Models, Animal|FBLN5 protein, human|PRSS3 protein, human|Trypsin" 13 PRSS35 23353556 Nat. Med. 2013 PMC4457508 10.1038/nm.2989 44 25 4 22 "Humans|Mice|Animals|*Fibrosis|*Fibroblast|Kidney Diseases|Kidney|WFDC2 protein, human|*WAP Four-Disulfide Core Domain Protein 2|Type I Collagen|Myofibroblasts|Biomarkers|Disease Models, Animal|PRSS23 protein, mouse|Serine Endopeptidases" 13 PRSS35 23451081 PLoS ONE 2013 PMC3579851 10.1371/journal.pone.0056757 12 14 2 22 "Pregnancy|Female|Mice|Animals|*Serine Proteases|Embryo Implantation|Progesterone|Uterus|*Serine Endopeptidases|Oestradiol|*Fertility|Corpus Luteum|Embryo Development|Blotting, Northern|Estrogens|Ovary|RNA, Messenger|Gene Expression|Superovulation|PRSS23 protein, mouse" 13 PRSS35 23437119 PLoS ONE 2013 PMC3577807 10.1371/journal.pone.0056376 10 12 3 22 "Female|Humans|Mice|Animals|*Protease Inhibitors|*Pelvic Organ Prolapse|Vagina|Uterine Prolapse|Matrix Metalloproteinase 9|Elastic Fibers|Extracellular Matrix Proteins|*Endopeptidases|Proteases|*Disease Models, Animal|FBLN5 protein, human|PRSS3 protein, human|Trypsin" 13 PRSS35 23353556 Nat. Med. 2013 PMC4457508 10.1038/nm.2989 44 25 4 22 "Humans|Mice|Animals|*Fibrosis|*Fibroblast|Kidney Diseases|Kidney|WFDC2 protein, human|*WAP Four-Disulfide Core Domain Protein 2|Type I Collagen|Myofibroblasts|Biomarkers|Disease Models, Animal|PRSS23 protein, mouse|Serine Endopeptidases" 13 RILPL2 24136289 Mol Biosyst 2013 PMC4171131 10.1039/c3mb70343f 15 7 0 24 Humans|*Hepacivirus|*Hepatitis C|Virus Replication|Host-Pathogen Interactions|Lipid Metabolism|siRNA|Lipids 13 RILPL2 23798443 Proc. Natl. Acad. Sci. U.S.A. 2013 PMC3710815 10.1073/pnas.1306768110 17 0 1 24 "Humans|Animals|MYO5A protein, human|Myosin Type V|*Myosins|Myosin Heavy Chains|Protein Conformation|Protein Binding|Binding Sites|MLPH protein, human|Adaptor Proteins, Signal Transducing|Saccharomyces cerevisiae|Models, Molecular|Isoforms" 13 SRBD1 24040232 PLoS ONE 2013 PMC3770690 10.1371/journal.pone.0074372 5 4 0 43 "Dogs|Humans|Animals|*Glaucoma|Glaucoma, Primary Open Angle|SNPs|Genetic Predisposition to Disease|Intraocular Pressure|Gene Frequency|Genome-Wide Association Study|Genotype|Genetic Testing|Optic Neuropathy|*Tetrahymenina|Intron" 13 TBX10 23649242 Biosci. Biotechnol. Biochem. 2013 10.1271/bbb.121017 2 0 1 6 "Humans|Mice|Animals|*Teratogens|Tetrachlorodibenzo-p-dioxin|*Gene Expression Regulation|*Teratogenesis|Receptors, Aryl Hydrocarbon|Retinoic Acid|Fetal Development|*Complement Factor B|RNA, Messenger|3'-(1-butylphosphoryl)adenosine|DLX4 protein, human|Transcription Factors|Homeodomain Proteins" 13 BAIAP3 22587803 Clin Sarcoma Res 2012 PMC3351707 10.1186/2045-3329-2-3 2 5 0 29 "Humans|Male|Female|Adult|*Reverse Transcriptase Polymerase Chain Reaction|*Desmoplastic Small Round Cell Tumor|EWSR1 protein, human|RNA-Binding Protein EWS|Translocation, Genetic|Oncogene Proteins, Fusion|Ewings Sarcoma|*Cytogenetic|Zinc Fingers|WT1 Proteins|Oncogenes|Promoter Regions, Genetic|platelet-derived growth factor A|Platelet-Derived Growth Factor|Cytogenetic Analysis|MLF1 protein, human|Proteins|BAIAP3 protein, human" 13 BCL7C 22442726 PLoS ONE 2012 PMC3307773 10.1371/journal.pone.0033834 42 18 3 77 "Male|Animals|Humans|Chromosomal Proteins, Non-Histone|Transcription Factors|Nuclear Proteins|ATPases|Synovial Sarcomas|Nucleosome|Oncogenes" 13 BTBD10 22490816 Zhonghua Nei Ke Za Zhi 2012 0 6 0 44 Proto-Oncogene Proteins c-akt|*Islet Cell|TOR Serine-Threonine Kinases|Signal Transduction|Phosphorylation|Cell Proliferation|Sirolimus|Cell Survival|Cell Line 13 BTBD10 22388351 Cell Death Differ. 2012 PMC3392628 10.1038/cdd.2012.19 9 4 0 44 "Mice|Humans|Animals|*Proto-Oncogene Proteins c-akt|Caenorhabditis elegans|*Motor Neuron|Amyotrophic lateral sclerosis 1|Amyotrophic Lateral Sclerosis|SOD1 G93A protein|Superoxide Dismutase|*Cell Death|Mice, Transgenic|Protein Phosphatase 2A|RNA, Small Interfering|Cell Line|Mutation" 13 CPAMD8 22412388 PLoS Genet. 2012 PMC3297573 10.1371/journal.pgen.1002559 67 4 2 5 "Humans|*Crohn Disease|Genome-Wide Association Study|*Jews|Genetic Susceptibility|Polymorphism, Single Nucleotide|Haplotypes|Genotype|Nod2 Signaling Adaptor Protein|Case-Control Studies|CPAMD8 protein, human|alpha-Macroglobulins|Complement C3|Trypsin Inhibitor, Kazal Pancreatic" 13 DMRTA1 23175770 Biol. Reprod. 2012 10.1095/biolreprod.112.105130 7 0 0 70 "Animals|Male|*Zebrafish|*Cyclin-Dependent Kinase Inhibitor p18|*Testis|Zebrafish Proteins|*Spermatogenesis|Transcription Factors|Homeodomain Proteins|TCF3 protein, human|Basic Helix-Loop-Helix Transcription Factors|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Telencephalon|Animals, Genetically Modified|Promoter Regions, Genetic|Fibroblast Growth Factor|Embryonic Development" 13 DNAJB12 23018488 Cell Struct. Funct. 2012 10.1247/csf.12017 12 3 2 28 "Mice|Animals|*Endoplasmic Reticulum-Associated Degradation|*Protein A|*Endoplasmic Reticulum|CFTR protein, human|Cystic Fibrosis Transmembrane Conductance Regulator|HSP40 Heat-Shock Proteins|Ubiquitin|Proteasome|Ubiquitination|Protein Transport|HSP70 Heat-Shock Proteins|HSC70 Heat-Shock Proteins|Protein Folding|Cytosol|Saccharomyces cerevisiae|Ubiquitin-Protein Ligases|Proteasome Inhibitor" 13 FNDC3A 22448450 J Investig Allergol Clin Immunol 2012 9 0 0 117 "Humans|FN1 protein, human|*Fibronectins|*Actins|*Bronchus, Primary|*Fibroblasts|*Asthma|Myofibroblasts|Cytoskeletal Proteins|Muscle, Smooth|Muscle Proteins|Smooth Muscle Cells|Cells, Cultured" 13 FOCAD 22427331 Brain 2012 10.1093/brain/aws045 15 1 2 27 "Humans|Animals|Mice|*Focal Adhesions|Comparative Genomic Hybridization|*Gliomas|Glioblastoma|*Cell Adhesion|*Genes, Tumor Suppressor|Brain Neoplasms|Cell Line, Tumor|Cell Movement|Gene Expression Regulation, Neoplastic|Messenger RNA|Xenograft Model Antitumor Assays|Transplantation, Heterologous|FOCAD protein, human|Tumor Suppressor Proteins" 13 GSX1 23042297 J. Comp. Neurol. 2012 PMC3615175 10.1002/cne.23242 26 52 1 108 "Mice|Animals|*Transcription Factors|Homeodomain Proteins|Cell Differentiation|Telencephalon|OLIG2 protein, human|Oligodendrocyte Transcription Factor 2|Neurogenesis|Neural Stem Cells|Homeo Box Genes|*Phenotypes|Gene Expression Regulation, Developmental|Ganglia|Neurons|Embryo, Mammalian|Cell Movement|Cerebral Cortex" 13 HYAL4 23086929 J. Biol. Chem. 2012 PMC3516757 10.1074/jbc.M112.360693 8 0 1 7 "Male|Pregnancy|Female|Mice|Humans|Animals|*Chondroitin Sulfates|*Substrate Specificity|*Hyaluronoglucosaminidase|*Hydrolases|Glucuronic Acid|Amino Acid Sequence|*Amino Acids|Cloning, Molecular|Sequence Homology, Amino Acid" 13 IQSEC3 22886754 J. Comp. Neurol. 2012 10.1002/cne.23206 7 0 1 41 "Animals|Mice|*Guanine Nucleotide Exchange Factors|*Brefeldin A|Synapses|gephyrin|Membrane Proteins|Retina|ADP-Ribosylation Factors|Disks Large Homolog 4 Protein|Retinal Rod Photoreceptor Cells|Microscopies, Immunoelectron|Retinal Cone Photoreceptor Cells|glutamate receptor ionotropic, AMPA 3|Receptors, AMPA|Nerve Tissue Proteins|Receptors, N-Methyl-D-Aspartate|Iqsec1 protein, mouse" 13 PRSS35 23092984 Transl Psychiatry 2012 PMC3565814 10.1038/tp.2012.106 26 4 1 22 "*Bipolar Disorder|*Genome-Wide Association Study|Schizophrenia|Psychoses|*Genome|Genetic Linkage|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Phenotype" 13 PRSS35 23092984 Transl Psychiatry 2012 PMC3565814 10.1038/tp.2012.106 26 4 1 22 "*Bipolar Disorder|*Genome-Wide Association Study|Schizophrenia|Psychoses|*Genome|Genetic Linkage|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Phenotype" 13 RILPL2 23264467 Mol. Biol. Cell 2012 PMC3571868 10.1091/mbc.E12-08-0598 14 20 0 24 "Humans|Mice|Animals|*Cilia|Centrioles|*Proteins|Cells, Epithelial|Centrosome|Cell Line|Carrier Proteins|Protein Transport|Microtubule|Signal Transduction|Protein Binding|Transcriptional Activation|RILP protein, human|Adaptor Proteins, Signal Transducing" 13 SFTA2 23094088 PLoS ONE 2012 PMC3475697 10.1371/journal.pone.0047789 6 1 0 275 Humans|*Pulmonary Surfactants|Pulmonary Surfactant-Associated Protein A|Lung|Phospholipids|Surface Tension|Amino Acid Sequence|*Surface-Active Agents|Molecular Dynamics Simulation|*Lipoproteins|Posttranslational Modifications 13 SFTA2 22768197 PLoS ONE 2012 PMC3386909 10.1371/journal.pone.0040011 5 7 0 275 Mice|Humans|Animals|*Hyperoxia|*Lipopolysaccharides|*Lung|Type-II Pneumocytes|Pulmonary Alveoli|*Peptides|mRNA|Pulmonary Surfactant-Associated Protein A|Epithelium|*Biological Transport|Proteins 13 SPECC1 22846151 Genes Brain Behav. 2012 PMC3508728 10.1111/j.1601-183X.2012.00820.x 13 0 0 213 "Mice|Animals|*Avoidance Learning|*Mice, Inbred C57BL|*Mice, Inbred DBA|*Genotypes|Memory|Species Specificity" 13 SRBD1 22761751 PLoS ONE 2012 PMC3384655 10.1371/journal.pone.0039278 36 8 2 43 "Humans|Barbados|*Glaucoma, Primary Open Angle|SNPs|Alleles|Genotype|Gene Frequency|Genetic Predisposition to Disease|Cyclin-Dependent Kinase Inhibitor p15|Homeodomain Proteins|Case-Control Studies|*Genes, cdc|Trans-Activators|West Indies|CDC7 protein, human|Protein-Serine-Threonine Kinases|Cell Cycle Proteins|CDKN2B protein, human" 13 SRBD1 22605921 Mol. Vis. 2012 PMC3351427 22 0 0 43 "*Genome-Wide Association Study|*Glaucoma, Primary Open Angle|*Phenotype|Intraocular Pressure|Optic Neuropathy|Optic Disk|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype" 13 SRRD 22235947 Alcohol. Clin. Exp. Res. 2012 PMC3334457 10.1111/j.1530-0277.2011.01699.x 14 1 0 66 Alcohol Dependence|Alcoholic Intoxication|Ethanol|Alcohol Drinking|Questionnaire|Risk Factors 13 TFDP3 23212661 Hepatology 2012 PMC3594482 10.1002/hep.26188 27 32 3 176 "Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Transcription Factor 3|Mice, Nude|*Dimerization|endothelial PAS domain-containing protein 1|*Basic Helix-Loop-Helix Transcription Factors|TCF3 protein, human|HNF1A protein, human|*Hepatocyte Nuclear Factor 1-alpha|Gene Expression Regulation, Neoplastic|Downregulation|Up-Regulation|Apoptosis|Short Hairpin RNA|Cell Line, Tumor|Quantitative Real Time Polymerase Chain Reaction|E2F Transcription Factors" 13 TFDP3 22482402 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2012 0 2 0 176 "Humans|Male|*Apoptosis|*Autophagy|Transcription Factor DP1|E2F1 Transcription Factor|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Prostate Cancer|TFDP3 protein, human" 13 ZNF385B 23253381 BMC Genomics 2012 PMC3562524 10.1186/1471-2164-13-711 6 0 2 17 "Swine|Humans|Animals|*Obesity|*Phenotype|Chromosome Mapping|Quantitative Trait Loci|Genetic Linkage|Genetic Predisposition|*Comparative Genomics|Chromosomes, Human" 13 ZNF385B 23029477 PLoS ONE 2012 PMC3460818 10.1371/journal.pone.0046317 9 12 1 17 "Humans|Female|*Cystadenocarcinoma, Serous|*Carcinoma, Ovarian Epithelial|Ovarian Cancer|Prognosis|Gene Expression Regulation, Neoplastic|*Transcription Factors|Biomarkers, Tumor|mRNA|Gene Expression Profiling|Disease-Free Survival|VEGFA protein, human|Vascular Endothelial Growth Factor A" 13 ZNF385B 22945289 Eur. 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Teratol. 2011 10.1002/bdra.20788 0 4 1 49 "Mice|Humans|Animals|*Cleft Lip|Cleft Palate|*Mice, Inbred Strains|Crosses, Genetic|Disease Models, Animal|Mutation|*Epigenetic|Wnt Proteins|Palate|Epigenesis, Genetic" 13 FKBP2 21831322 BMC Genomics 2011 PMC3176260 10.1186/1471-2164-12-408 91 0 11 95 "Cattle|Female|Animals|*Genome-Wide Association Study|*Reproduction|*Phenotypes|Breeding|Lactation|Dairying|Quantitative Trait Loci|Quantitative Trait, Heritable|Milk|Genotype|Fertility|Genetic Selection|Polymorphism, Single Nucleotide" 13 FNDC3A 21906182 J. Anim. Breed. Genet. 2011 10.1111/j.1439-0388.2011.00927.x 5 0 1 117 "Animals|*Quantitative Trait Loci|*Chickens|*Phenotype|Chromosome Mapping|Microsatellite Marker|Genotype|Linkage Disequilibrium|Haplotypes|Single Nucleotide Polymorphism|*Genetic Techniques|*Bone|*Genes, cdc|Cloning, Molecular" 13 GSX1 21205889 Proc. Natl. Acad. Sci. 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Dev. 2009 PMC2703006 10.1016/j.mod.2009.03.008 4 5 2 108 "Animals|*Transcriptional Activation|*Neural Stem Cells|Proteins, Homeo Domain|Drosophila|Drosophila Proteins|Transcription Factors|Drosophila melanogaster|*Central Nervous System|Homeobox|Body Patterning|Gene Expression Regulation, Developmental|Neuroectoderm|Embryo, Nonmammalian|SOX Transcription Factors|Amino Acid Sequence" 13 GSX1 19208224 Neural Dev 2009 PMC2644683 10.1186/1749-8104-4-5 32 6 1 108 "Animals|Mice|Telencephalon|Homeodomain Proteins|Homeobox Gene|Cell Differentiation|Neural Stem Cells|Gene Expression Regulation, Developmental|*Phenotype|Transcription Factors|Ganglia|Neurons|Corpus Striatum|Ascl1 protein, mouse|Basic Helix-Loop-Helix Transcription Factors|Gsh2 protein, mouse" 13 HSPB9 19159671 Toxicol In Vitro 2009 10.1016/j.tiv.2008.12.023 7 9 2 26 "Humans|*Cyclosporine|*Transcriptome|Reproducibility of Results|*Tubule, Proximal Renal|DNA Microarrays|Immunosuppressive Agents|Gene Expression Profiling|Cell Line|Clustering|Kidney|Cell Cycle|Nucleic Acid Hybridization|Signal Transduction" 13 LAMB4 19435607 Mol. Phylogenet. Evol. 2009 10.1016/j.ympev.2009.05.004 1 0 0 2 "Phylogeny|*Lycopodiaceae|*Polyploids|*Genetic Evolution|DNA, Chloroplast|Diploids|DNA, Plant|Sequence Alignment|DNA, Ribosomal Spacer|Genetic Variation|Sequence Analysis, DNA|Cell Nucleus|Asia|Madagascar|South Africa" 13 LIMCH1 19268448 Dev. Biol. 2009 PMC2697309 10.1016/j.ydbio.2009.02.023 16 14 0 160 "Humans|Mice|Animals|Somites|*Embryonic Development|Mesoderm|Intracellular Signaling Peptides and Proteins|NRARP protein, human|*Neoplasm Proteins|Membrane Proteins|Body Patterning|Receptors, Notch|Signal Transduction|Gene Expression Regulation, Developmental|AXIN2 protein, human|Axin Protein|Mutation|In Situ Hybridization|DLL3 protein, human|Lfng protein, mouse|Glycosyltransferases" 13 RILPL2 19812310 J. Cell. Sci. 2009 PMC2758809 10.1242/jcs.050344 11 5 0 24 *Myosin B|*Cell Shape|*Neurons|Myosin Type V|Dendritic Spines|*Morphogenesis|Hippocampus|*Signal Transduction|Myosin Heavy Chains|Neurogenesis|Protein Transport|Short Hairpin RNA|Proteins|Protein Binding|p21-Activated Kinases 13 BCL7C 18172295 Cancer Res. 2008 10.1158/0008-5472.CAN-07-2531 53 3 6 77 "Humans|*Decitabine|trichostatin A|Epigenesis, Genetic|*Multiple Myeloma|*Hydroxamic Acids|Histone Deacetylase Inhibitors|DNA Modification Methylases|Azacitidine|DNA Methylation|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|Histone Deacetylases|Acetylation|Inactivation, Gene|Histones|Genes, cdc|Downregulation|Up-Regulation" 13 DNAJB5 18555775 Cell 2008 10.1016/j.cell.2008.04.041 139 4 2 67 "*Cardiac Hypertrophy|HDAC4 protein, human|*Class II Histone Deacetylases|*Redox|Repressor Proteins|Thioredoxin 1|Signal Transduction|Phosphorylation|Export, Nuclear|Myocytes, Cardiac|Cell Nucleus|Amino Acid Sequence|Transcription Factors|Reactive Oxygen Species|Cysteine|Protein Transport" 13 DNAJB5 18340362 Genes Immun. 2008 10.1038/gene.2008.11 5 0 0 67 "Humans|*Inflammatory Bowel Diseases|Colitis, Ulcerative|Crohn's Disease|*Gene Expression|TNF protein, human|Tumor Necrosis Factor alpha|Colon|Intestinal Mucosa|RNA, Messenger|Interleukin|Biopsy|*Cell Line" 13 FKBP2 19107525 Mol. Genet. Genomics 2008 10.1007/s00438-008-0413-7 5 0 0 95 "Female|Humans|Animals|*Deer|Antler|*Osteoporosis|Bone Mineral Density|Oligonucleotide Array Sequence Analysis|Osteoporosis, Postmenopausal|Gene Expression Profiling|Bone|RNA, Messenger|Regeneration" 13 FKBP2 18448419 Mol. Cell Proteomics 2008 PMC2500228 10.1074/mcp.M700478-MCP200 50 0 2 95 "Mice|Animals|*Diabetes Mellitus, Type 2|*Proteomics|Endoplasmic Reticulum-Associated Degradation|Pancreatic beta Cells|Insulin|Insulin Resistance|Islets of Langerhans|Insulin Secretion|Proteome|Energy Metabolism|Mitochondria|Mice, Transgenic|Gene Expression|Blotting, Western|Muscle, Skeletal" 13 FNDC3A 18218838 J. Dent. 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Chem. 2008 10.1074/jbc.M805828200 19 3 3 920 "Mice|Chlorocebus aethiops|Animals|ITPR1 protein, human|*Receptor, IP3|*Calcium|*Inositol 1,4,5-Trisphosphate|Calcium Signaling|Endoplasmic Reticulum|*Calcium, Dietary|COS-7 Cells|Protein Binding|Binding Protein|Recombinant Proteins|Neurons|Co-Immunoprecipitations" 13 LIMCH1 18553215 Mol. Biol. Rep. 2008 10.1007/s11033-008-9281-9 7 0 0 160 "Humans|*Alternative Splicing|Isoforms|Amino Acid Sequence|Exon|Intron|Sequence Alignment|Protein Structure, Tertiary|Gene Duplication|calponin|Calcium-Binding Proteins|Phylogeny|*Protein Domains|RNA, Messenger|Microfilament Proteins|Protein Binding|LMO7 protein, human|Transcription Factors|LIM Domain Proteins" 13 PRSS35 18566130 Endocrinology 2008 10.1210/en.2007-1736 10 1 1 22 "Female|Mice|Animals|*Ovary|*Serine Proteases|*Temperature|Follicular Atresia|Follicles, Atretic|Ovulation|*Serine Endopeptidases|Corpus Luteum|Granulosa Cells|Gonadotropins|Ovulation Induction|In Situ Hybridization|PRSS23 protein, mouse" 13 PRSS35 18566130 Endocrinology 2008 10.1210/en.2007-1736 10 1 1 22 "Female|Mice|Animals|*Ovary|*Serine Proteases|*Temperature|Follicular Atresia|Follicles, Atretic|Ovulation|*Serine Endopeptidases|Corpus Luteum|Granulosa Cells|Gonadotropins|Ovulation Induction|In Situ Hybridization|PRSS23 protein, mouse" 13 RASL11B 18197245 PLoS ONE 2008 PMC2186344 10.1371/journal.pone.0001434 4 30 1 35 "Animals|Humans|*Zebrafish|Zebrafish Proteins|Homeodomain Proteins|Transcription Factors|Endoderm|Body Patterning|Mesoderm|SMAD2 protein, human|Smad2 Protein|*Phenotype|Trans-Activators|Gene Expression Regulation, Developmental|Signal Transduction|TGFbeta|Embryogenesis|*Eye" 13 SPECC1 18763323 Cell Cycle 2008 10.4161/cc.7.12.6023 6 2 0 213 "Humans|Proteomics|nucleophosmin|Nuclear Proteins|*Adaptor Proteins, Signal Transducing|Cell Cycle Proteins|Isoforms|Mitosis|HeLa Cells|Apoptosis|siRNA" 13 TFDP3 18782520 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2008 0 0 0 176 "Humans|*Transcription Factors|*Antibodies|*Peptides|Antibody Specificity|Amino Acid Sequence|Cell Line|TFDP3 protein, human|Transcription Factor DP1" 13 BTBD10 18160256 Cell. Signal. 2007 10.1016/j.cellsig.2007.11.004 8 38 0 44 "Chlorocebus aethiops|Animals|Amyotrophic Lateral Sclerosis, Autosomal Recessive|Amyotrophic lateral sclerosis 1|*Amyotrophic Lateral Sclerosis|AKT3 protein, human|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Protein Phosphatase 2A|*Superoxide Dismutase-1|*Cell Adhesion|*Superoxide Dismutase|Motoneurons|Cell Death|Phosphorylation|Upregulation|Mutation|COS Cells" 13 ITPRIP 17301879 PLoS ONE 2007 PMC1784063 10.1371/journal.pone.0000204 10 4 0 920 "Animals|Evolution, Molecular|Multigene Family|Phylogeny|Amino Acid Sequence|Invertebrates|Sequence Homology, Amino Acid|Membrane Proteins|Carrier Proteins|Cell Differentiation" 13 RASL11B 17628721 Biochim. Biophys. Acta 2007 10.1016/j.bbaexp.2007.05.005 8 3 0 35 "Humans|Pregnancy|Female|Exons|TATA Box|Base Sequence|Introns|Promoter Regions, Genetic|*Genomics|Amino Acid Sequence|Cloning, Molecular|Transcription Factors|Transcription, Genetic|DNA, Complementary|mRNA|Binding Sites|Chromosome Mapping|Transfection" 13 RASL11B 17504929 Neuro-oncology 2007 PMC1907422 10.1215/15228517-2007-009 22 0 0 35 "Humans|*Glioblastoma|Glioma|Brain Neoplasms|Gene Amplification|Oligodendrogliomas|Astrocytomas|Oligonucleotide Array Sequence Analysis|Gene Dosage|Gene Expression Profiling|*Chromosome Structures|Transcription Factors|Genes, Regulator" 13 TFDP3 17632080 Biochem. Biophys. Res. Commun. 2007 10.1016/j.bbrc.2007.06.128 10 6 1 176 "Humans|*Tumor Suppressor Protein p53|HEK293 Cells|*Apoptosis|Transcription Factor DP1|E2F1 Transcription Factor|DNA-Binding Proteins|E2F Transcription Factors|Cell Cycle Proteins|Transcriptional Activation|Apoptosis Regulatory Proteins|Cell Line, Tumor|E2F1 protein, human|TFDP3 protein, human" 13 DMRTA1 16982677 Mol. Cell. Biol. 2006 PMC1636805 10.1128/MCB.00959-06 13 0 0 70 Male|Female|Mice|Animals|Transcription Factors|DNA-Binding Proteins|*Ovarian Follicle|Sexual Differentiation|Ovaries|Zinc Finger|*Fertility|Gonads|Gene Expression Profiling 13 DSTYK 17123648 Biochim. Biophys. Acta 2006 PMC4277547 10.1016/j.bbaexp.2006.10.004 4 0 1 199 "Humans|Animals|*Catalytic Domain|*Genetic Evolution|Amino Acid Sequence|Sequence Alignment|Conserved Sequence|Protein Kinases|Protein-Serine-Threonine Kinases|Sequence Homology, Amino Acid|Cytoplasm|Cloning, Molecular|DNA, Complementary|Green Fluorescent Proteins|Phylogeny|Blotting, Northern" 13 FNDC3A 16904100 Dev. Biol. 2006 PMC3049804 10.1016/j.ydbio.2006.06.054 23 0 1 117 "Humans|Male|Mice|Animals|*Spermatids|*Sertoli Cells|Spermatogenesis|Testis|Seminiferous Epithelium|Male Sterility|Acrosome|Amino Acid Sequence|Cell Adhesion|Proteins|Gene Expression|Binding Site|FNDC3A protein, human|Fibronectins" 13 ITPRIP 16990268 J. Biol. Chem. 2006 10.1074/jbc.M608760200 16 1 3 920 "*Inositol 1,4,5-Trisphosphate|Inositol 1,4,5-Trisphosphate Receptors|Ion Channel Gating|Calcium|Protein Binding|*Transcription Factors" 13 PRSS35 16870946 Biol. Reprod. 2006 10.1095/biolreprod.106.052290 11 0 0 22 "Humans|Female|Mice|Rats|Cattle|Animals|Dogs|*Ovary|*Computational Biology|*Proteases|Macaca mulatta|Ovulation|Ovarian Follicle|Granulosa Cells|Theca Cells|*Genomics|Serine Endopeptidases|Amino Acid Sequence|Base Sequence|Progesterone|Ovulation Induction|Gene Expression|PRSS23 protein, mouse" 13 PRSS35 16870946 Biol. Reprod. 2006 10.1095/biolreprod.106.052290 11 0 0 22 "Humans|Female|Mice|Rats|Cattle|Animals|Dogs|*Ovary|*Computational Biology|*Proteases|Macaca mulatta|Ovulation|Ovarian Follicle|Granulosa Cells|Theca Cells|*Genomics|Serine Endopeptidases|Amino Acid Sequence|Base Sequence|Progesterone|Ovulation Induction|Gene Expression|PRSS23 protein, mouse" 13 TFDP3 17062573 J. Biol. Chem. 2006 10.1074/jbc.M606169200 12 2 0 176 "Humans|*Transcriptional Activation|Transcription Factors|DNA-Binding Proteins|Transcription Factor DP1|Cell Cycle Proteins|E2F Transcription Factors|Amino Acid Sequence|Transcription, Genetic|Repressor Proteins|Cell Cycle|Sequence Homology, Amino Acid|Protein Binding|Cell Division|Dimerization|DNA|TFDP3 protein, human" 13 CNTNAP3 15820314 Genomics 2005 10.1016/j.ygeno.2005.01.002 3 1 0 49 "Humans|*Translocation, Genetic|In Situ Hybridization, Fluorescence|*Bladder Exstrophy|*Chromosome 9|Chromosome Breakage|Base Sequence|Chromosome Inversion|Chromosomes, Artificial, Bacterial|CNTNAP3 protein, human|Membrane Proteins|Nerve Tissue Proteins" 13 FKBP2 15792627 Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2005 10.1016/j.cca.2005.01.007 5 2 0 95 "Humans|Male|Animals|*Hypericum|nonylphenol|*Flounder|*Testosterone|*Acute Phase Proteins|*Phenols|NR1I2 protein, human|Pregnane X Receptor|Liver|Cytochrome P-450 CYP3A|Gene Expression|Hydroxylation|*Testosterone Congeners|Plant Extracts|*Plant Oils|Steroids" 13 HSPB9 16111033 Wei Sheng Yan Jiu 2005 0 0 0 26 "Mice|Animals|*Cleft Palate|*Palate|*Embryogenesis|*Heat-Shock Proteins, Small|Tretinoin|Mice, Inbred ICR|Gene Expression Regulation, Developmental|Heat-Shock Proteins|RNA, Messenger" 13 HYAL4 16330764 Proc. Natl. Acad. Sci. U.S.A. 2005 PMC1312394 10.1073/pnas.0506825102 30 1 1 7 Male|Female|Mice|Animals|*Hyaluronoglucosaminidase|Sperm Penetration|*Sperm|Zona Pellucida|Cumulus Cells|Epididymis|Fertilization|Acrosome Reaction|Acrosome|Oocytes|Testis|Cell Adhesion Molecules|Hyaluronan|Sperm Tail 13 LAMB4 16228230 Hum. Genet. 2005 10.1007/s00439-005-0064-2 3 0 0 2 "Humans|*Cardiomyopathy, Dilated|Genetic Linkage|Pedigree|Lod Score|Chromosome Mapping|*Chromosome 1|Phenotypes|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Penetrance|Mutations|*Chromosome Structures|LAMB1 protein, human|Laminin" 13 SRRD 16258652 Arq Neuropsiquiatr 2005 10.1590/s0004-282x2005000500008 5 0 0 66 Child|Humans|*Sleep Disorders|*Impulsivity|Sleep|Child Behavior Disorders|Emotions 13 TBX10 16327884 PLoS Genet. 2005 PMC1298935 10.1371/journal.pgen.0010064 70 6 3 6 "Humans|Animals|Child|*Cleft Lip|Cleft Palate|MSX1 Transcription Factor|Linkage Disequilibrium|Mutation|Homeodomain Proteins|Polymorphism, Single Nucleotide|Transcription Factors|*Palate|*Sequence Analysis|FOXE1 protein, human|Forkhead Transcription Factors|SPRY2 protein, human|Membrane Proteins|Intracellular Signaling Peptides and Proteins|SATB2 protein, human|Matrix Attachment Region Binding Proteins" 13 TBX10 16247549 J. Hum. Genet. 2005 10.1007/s10038-005-0319-8 16 0 0 6 "Humans|Mice|Animals|*Cleft Lip|*Cleft Palate|TGFB3 protein, human|*Transforming Growth Factor beta3|Japan|MSX1 Transcription Factor|Haplotypes|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Alleles|Exon|Transforming Growth Factor alpha|Case-Control Studies|Transcription Factors|Homeodomain Proteins|Genetic Variation|Genetic Association Studies|CLPTM1 protein, human" 13 TBX10 15703190 Hum. Mol. Genet. 2005 10.1093/hmg/ddi081 31 0 1 6 "Humans|Mice|Animals|*DiGeorge Syndrome|*Nuclear Localization Signals|Shprintzen Golberg craniosynostosis|*Arachnodactyly|Brachyury protein|T-Box Domain Proteins|*Marfan Syndrome|*Craniosynostoses|*Mutation|Fetal Proteins|Nuclear Proteins|Chromosome Deletion|Disease Models, Animal|TBX1 protein, human|Tbx1 protein, mouse" 13 BCL7C 15547684 Int. J. Mol. Med. 2004 5 0 0 77 "Humans|Mice|Animals|Base Sequence|Amino Acid Sequence|Bioinformatics|Sequence Alignment|Exons|Chromosome Mapping|CXXC5 protein, human|Carrier Proteins|Transcription Factors|Genome, Human|Sequence Homology, Amino Acid|Protein Structure, Tertiary|Expressed Sequence Tags|*In Silico|cDNA|BCL7A protein, human|Microfilament Proteins|Oncogene Proteins" 13 BCL7C 15270555 Cancer Immun. 2004 4 2 0 77 "Mice|Animals|IL10 protein, human|*Interleukin-10|*RNA Interference|*B-Lymphocyte Subsets|Leukemia, Lymphocytic, Chronic, B-Cell|B-Lymphocytes|Apoptosis|Proto-Oncogene Proteins c-bcl-2|RNA, Small Interfering|Anti-Apoptotic Proteins|Tumor Cells, Cultured|NZB Mouse|Downregulation|RNA, Messenger|ELISA" 13 BTBD10 15556295 Gene 2004 10.1016/j.gene.2004.05.028 5 0 0 44 "Male|Female|Adult|Humans|*BTB-POZ Domain|HEK293 Cells|*Cloning, Molecular|cDNA|*Glioma|Exons|Northern Blot|Amino Acid Sequence|Base Sequence|cDNA Library|Sequence Alignment|Green Fluorescent Proteins|Luminescent Proteins|Introns|*Protein Binding|Open Reading Frame|Cell Nucleus|Gene Expression Profiling" 13 CPAMD8 15262283 Insect Biochem. 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Biol. 2004 10.1016/j.ibmb.2004.04.003 9 0 0 5 "Humans|Animals|farnesoic acid O-methyltransferase|*Nephropidae|*Methyltransferases|Amino Acid Sequence|methyl farnesoate|Fatty Acids, Unsaturated|Base Sequence|cDNA|mRNA|Drosophila Proteins|Hepatopancreas|Crustacea|*Food Hypersensitivity|PCR|CPAMD8 protein, human|alpha-Macroglobulins|Complement C3|Trypsin Inhibitor, Kazal Pancreatic" 13 CPAMD8 15177561 Genomics 2004 10.1016/j.ygeno.2003.12.005 8 1 1 5 "Humans|Male|Female|Pregnancy|*Complement C3|*Pregnancy-Associated alpha 2-Macroglobulins|*Kazal Motifs|Amino Acid Sequence|Sequence Alignment|Base Sequence|Exons|cDNA|Cloning, Molecular|alpha-Macroglobulins|Sequence Homology, Amino Acid|Phylogeny|Proteins|CPAMD8 protein, human|Trypsin Inhibitor, Kazal Pancreatic" 13 DMRTA1 15478606 Yi Chuan Xue Bao 2004 0 0 0 70 "Humans|Mice|Swine|Animals|*Ursidae|Phylogeny|Caenorhabditis elegans|Amino Acid Sequence|DNA|Transcription Factors|Intron|(S-dinitrophenyl)-6-mercaptopurine riboside triphosphate|*Thionucleosides|*Adenosine Triphosphate|Gonads|DNA Primers|Cloning, Molecular" 13 DSTYK 15178406 Biochem. Biophys. Res. Commun. 2004 10.1016/j.bbrc.2004.04.194 13 3 1 199 "Caspases|*Cell Death|Apoptosis|Serine-Threonine Kinase, RIP|NF-kappa B|Caspase Inhibitors|Caspase 3|Signal Transduction|Enzyme Activation|Amino Acid Sequence|DNA Fragmentation|Sequence Homology, Amino Acid" 13 GSX1 15533825 Gene Expr. Patterns 2004 10.1016/j.modgep.2004.05.006 12 0 2 108 "Animals|*Zebrafish|gsx1 protein, zebrafish|Zebrafish Proteins|Homeodomain Proteins|Hindbrain|*Spinal Cord|Genes, Homeobox|Gene Expression Regulation, Developmental|*Hypothalamus|Transcription Factors|Mesencephalon|Diencephalon|Embryonic Development" 13 HSPB9 15503857 Eur. J. Cell Biol. 2004 10.1078/0171-9335-00396 5 1 0 26 "Male|Mice|Animals|Humans|*Dyneins|*Testis|HSPB9 protein, human|*Heat-Shock Proteins|*Heat Shock|Spermatogenesis|t-Complex Genome Region|Microtubule-Associated Proteins|Nuclear Proteins|Amino Acid Sequence|Yeast Two-Hybrid System|Base Sequence|Northern Blotting|Cytoplasm|Heat-Shock Proteins, Small" 13 REG1P 14742701 Mol. Biol. Cell 2004 PMC379254 10.1091/mbc.e03-12-0877 21 3 2 0 *Saccharomyces cerevisiae|*Actins|*Glucose|Saccharomyces cerevisiae Proteins|Transcription Factors|DNA-Binding Proteins|Protein Kinase|Protein-Serine-Threonine Kinases|Phosphorylation|Protein Binding 13 SPECC1 15087372 Cancer Res. 2004 10.1158/0008-5472.can-03-4026 7 0 0 213 "*Receptor, Platelet-Derived Growth Factor beta|In Situ Hybridization, Fluorescence|*Leukemia, Myelomonocytic, Juvenile|Translocation, Genetic|Imatinib Mesylate|Gene Fusion|Piperazines|Benzamides|Myeloproliferative Disorders|Pyrimidines|Receptor Protein-Tyrosine Kinases|Cloning, Molecular|*Transcription Factors" 13 SRRD 15457731 Stud Health Technol Inform 2004 2 0 0 66 Humans|Male|Female|Adolescent|*Scoliosis|Reproducibility of Results|*Rib|*Kyphosis|Thoracic Vertebrae|*Ultrasonography|Lumbar Vertebrae|Radiography|Transducer|Torsion Abnormality|Prone Position|*Prostate 13 TBX10 15372236 Dev. Genes Evol. 2004 10.1007/s00427-004-0433-1 14 0 1 6 "Animals|*Lancelets|*Branchial Region|Phylogeny|*Vertebrate|Somites|Neural Crest|Mesoderm|DNA-Binding Proteins|Transcription Factors|Body Patterning|Biological Evolution|Evolution, Molecular|Amino Acid Sequence|Gene Expression Regulation, Developmental|Endoderm|In Situ Hybridization" 13 TBX10 15118109 Proc. Natl. Acad. Sci. U.S.A. 2004 PMC406459 10.1073/pnas.0401025101 16 2 0 6 "Mice|Animals|*Cleft Lip|*Gain of Function Mutation|Cleft Palate|Brachyury protein|T-Box Domain Proteins|In Situ Hybridization|Embryo, Mammalian|Homozygotes|Heterozygotes|Mice, Transgenic|Gene Expression Regulation, Developmental|Intron|Phenotype|Disease Models, Animal|Mutation|Fetal Proteins|*Palate" 13 HSPB9 12820655 Cell Stress Chaperones 2003 PMC514854 10.1379/1466-1268(2003)8<62:tsodfp>2.0.co;2 29 0 1 26 "Humans|Male|Animals|Phylogeny|Bayes Theorem|*Heat-Shock Proteins, Small|ODF1 protein, human|Heat-Shock Proteins|*Mammals|alpha-Crystallin|CRYAB protein, human|alpha-Crystallin B Chain|HSPB1 protein, human|HSP27 Heat-Shock Proteins|Sequence Alignment|Amino Acid Sequence|Binding Protein|Protein Binding|Sperm|HSPB2 protein, human" 13 HSPB9 12820654 Cell Stress Chaperones 2003 PMC514853 10.1379/1466-1268(2003)8<53:thgecs>2.0.co;2 107 0 3 26 "Humans|Animals|Male|*alpha-Crystallin|HSPB1 protein, human|*HSP27 Heat-Shock Proteins|*Heat-Shock Proteins 10|*Genome, Human|CRYAB protein, human|alpha-Crystallin B Chain|Heat-Shock Proteins, Small|Heat-Shock Proteins|Amino Acid Sequence|Base Sequence|Expressed Sequence Tag|HSPB2 protein, human" 13 REG1P 14684743 J. Biol. Chem. 2003 10.1074/jbc.M310793200 0 1 0 0 *Vacuoles|*Fructose-Bisphosphatase|*Fructose|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|*Phosphatases|Protein Transport|Glucose|Membrane Fusion|Cytosol|*Biochemical Phenomena 13 REG1P 12618390 Genetics 2003 PMC1462456 15 2 0 0 *Saccharomyces cerevisiae|SNF1-related protein kinases|*Protein-Serine-Threonine Kinases|Saccharomyces cerevisiae Proteins|Protein Phosphatase 1|Two-Hybrid Assays|Phosphorylation|Glucose|Catalytic Domain|Carrier Proteins|Signal Transduction|Protein Binding 13 TBX10 12915323 Gene Expr. Patterns 2003 10.1016/s1567-133x(03)00060-7 3 0 0 6 "Humans|Mice|Animals|In Situ Hybridization|*Embryogenesis|cDNA|T-Box Domain Proteins|Gene Expression Regulation, Developmental|Transcription Factors|Chromosome Mapping|Amino Acid Sequence|Chromosome|Open Reading Frame|RNA, Messenger" 13 BAIAP3 12498718 Cancer Cell 2002 10.1016/s1535-6108(02)00205-2 22 2 1 29 "RNA-Binding Protein EWS|*Cell Transformation, Neoplastic|Oncogene Proteins, Fusion|Ewings Sarcoma|*Tumorigenesis|Transcription Factor|Promoter Regions, Genetic|Genes, Wilms Tumor|Gene Expression Regulation|*Exocytosis|Carcinoma, Small Cell|*Chimera" 13 BAIAP3 12498708 Cancer Cell 2002 10.1016/s1535-6108(02)00210-6 7 1 0 29 "RNA-Binding Protein EWS|Oncogene Proteins, Fusion|Transcription Factors|Translocation, Genetic|WT1 Proteins|Base Sequence|Carcinoma, Small Cell|*Exocytosis" 13 CNTNAP3 12093160 Mol. Cell. Neurosci. 2002 10.1006/mcne.2002.1110 35 2 2 49 "*PDZ Domains|CNTNAP1 protein, human|*Cell Adhesion Molecules, Neuronal|Neurons|Nerve Tissue Proteins|Membrane Proteins|Axons|Cell Membrane|Cerebellum|Olfactory Bulb|Hippocampus|Amino Acid Sequence" 13 glocose 12126540 Zhonghua Yi Xue Za Zhi 2002 0 0 0 0 "*Insulin Resistance|*Diabetes Mellitus, Type 2|*Blood Glucose|*Pancreatic beta Cell|Glucose Tolerance Test|Insulin|Fasting|Islets of Langerhans|Hypoglycemic Agents|*Pancreas" 13 glocose 11774428 Zhonghua Kou Qiang Yi Xue Za Zhi 2002 2 0 0 0 Streptococcus mutans|Microbial Sensitivity Tests|Bacterial Adhesion|Plant Extracts|*Cucurbitaceae|Fruit|Anti-Bacterial Agents|Momordica 13 HYAL4 11944887 Biochem. Biophys. Res. Commun. 2002 10.1006/bbrc.2002.6697 11 1 1 7 "Humans|*Hyaluronoglucosaminidase|CD44 protein, human|*Hyaluronan Receptors|*Chondrogenesis|Hyaluronan Synthases|Hyaluronan|Up-Regulation|RNA, Messenger|DNA Primers|Cells, Cultured|Glycosaminoglycans|Fibroblasts|Hyal2 protein, human|Cell Adhesion Molecules|GPI-Linked Proteins" 13 REG1P 11773046 J. Biol. Chem. 2002 10.1074/jbc.M107255200 19 2 0 0 "*Saccharomyces cerevisiae|*Glucose|*Fructose-Bisphosphatase|*Fructose|*Proteolysis|Saccharomyces cerevisiae Proteins|Vacuole|*Yeast, Dried|*Membrane Transport Proteins|*Signal Transduction|Monosaccharide Transport Proteins|ATP dependent 26S protease|Proteasome|Biological Transport|Endocytosis|Protein Transport|*Carbohydrate Metabolism|Cytoplasm" 13 BAIAP3 11157797 Hum. Mol. Genet. 2001 10.1093/hmg/10.4.339 20 0 1 29 "Adult|Humans|Alpha-Thalassemia Mental Retardation Syndrome, Deletion-Type|alpha-Thalassemia|*Chromosome 16|Adult Polycystic Kidney Disease|Tuberous Sclerosis 2|Sclerosis, Tuberous|TRPP Cation Channels|Potter Type III Polycystic Kidney Disease|Polycystic Kidney Diseases|Chromosome Mapping|Chromosome Deletion|Intellectual Disability|Telomeres|BAIAP3 protein, human|Nerve Tissue Proteins" 13 DNAJB12 11147971 Cell Stress Chaperones 2001 PMC312896 10.1379/1466-1268(2000)005<0098:mhdhco>2.0.co;2 45 0 4 28 "Humans|Rats|Mice|Animals|*cDNA|DNAJB1 protein, human|*HSP40 Heat-Shock Proteins|DNAJB4 protein, human|Sequences, Amino Acid|Heat-Shock Proteins|Base Sequence|Sequence Alignment|Cloning, Molecular|HSP70 Heat-Shock Proteins|Sequence Homology, Amino Acid|*Mammals|Expressed Sequence Tag|Sequence Analysis, DNA" 13 DNAJB5 11682050 FEBS Lett. 2001 10.1016/s0014-5793(01)02923-4 2 2 0 67 "*Protein Renaturation|Escherichia coli Proteins|Bacteriophage lambda|HSP40 Heat-Shock Proteins|Heat-Shock Proteins|Escherichia coli|HSP70 Heat-Shock Proteins|Molecular Chaperones|Adenosine Triphosphatases|Bacterial Proteins|DNA Replication|DNA Polymerases|Amino Acid Sequence|DnaJ protein, E coli|dnaK protein, E coli" 13 HSPB9 11470154 Biochim. Biophys. Acta 2001 10.1016/s0167-4781(01)00237-8 24 0 0 26 "Male|Humans|Mice|Animals|*Heat-Shock Proteins, Small|*Testis|Heat-Shock Proteins|*Myosin-Light-Chain Kinase|Protein-Serine-Threonine Kinases|alpha-Crystallin|Amino Acid Sequence|HSP27 Heat-Shock Proteins|Spermatocyte|Sequence Homology, Amino Acid|HSPB8 protein, human|Hspb8 protein, mouse|Muscle Proteins|HSP20 Heat-Shock Proteins" 13 HYAL4 11731267 Matrix Biol. 2001 10.1016/s0945-053x(01)00172-x 131 0 7 7 "Mice|Humans|Animals|hyaluronidase PH-20|*Hyaluronoglucosaminidase|Amino Acid Sequence|Hyaluronan|Cell Adhesion Molecules|Pseudogene|Sequence Homology, Amino Acid|Hyal2 protein, human|GPI-Linked Proteins|Hyal1 protein, mouse|Hyal2 protein, mouse" 13 glocose 11026754 Exp. Clin. Endocrinol. Diabetes 2000 10.1055/s-2000-8137 5 0 1 0 "Humans|*Blood Glucose Self-Monitoring|*Blood Glucose|*Spectroscopy, Near-Infrared|Reproducibility of Results|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Sensitivity and Specificity|Calibration|*Monitoring, Physiologic|Algorithms" 13 HYAL4 10989127 J. Biochem. Biophys. Methods 2000 10.1016/s0165-022x(00)00067-1 4 1 0 7 "Pregnancy|Male|Humans|Female|Mice|Rats|Guinea Pigs|Rabbits|Animals|*Hyaluronoglucosaminidase|*Glycosylation|*Mammals|Sequences, Amino Acid|Hyaluronan|Sperm|*Diploidy|*Electrophoreses|*Body Fluids|Hyal2 protein, human|Cell Adhesion Molecules|GPI-Linked Proteins|Hyal1 protein, mouse|Hyal2 protein, mouse" 13 REG1P 10821175 Mol. Gen. Genet. 2000 10.1007/s004380051185 13 13 1 0 "*Saccharomyces cerevisiae|maltose permease|*Protein Phosphatase 1, Regulatory Subunit|*Glucose|*Monosaccharide Transport Proteins|Saccharomyces cerevisiae Proteins|Membrane Transport Proteins|*Transductions, Signal|Maltose|Biological Transport|Fermentation" 13 REG1P 10758001 Biochemistry 2000 10.1021/bi992455a 12 10 0 0 maltose permease|*Glucose|*Saccharomyces|*Proteolysis|*Monosaccharide Transport Proteins|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Membrane Transport Proteins|Biological Transport|Maltose|Vacuole|Phosphorylation|Signal Transduction|Endocytosis|Integral Membrane Protein 13 BCL7C 9931421 Gene 1999 10.1016/s0378-1119(98)00514-9 12 0 0 77 "Humans|Animals|*Williams Syndrome|Drosophila melanogaster|Base Sequence|Amino Acid Sequence|Sequence Alignment|Chromosome Mapping|Introns|Exons|Sequence Homology, Amino Acid|Gene Deletion|*Transcription Factors|Burkitt Lymphoma|In Situ Hybridization, Fluorescence|Caenorhabditis elegans|BCL7A protein, human|Microfilament Proteins|Oncogene Proteins" 13 DNAH17 10191081 Genomics 1999 10.1006/geno.1998.5740 1 0 0 54 "Humans|*Chromosome Mapping|Expressed Sequence Tags|Sequence Tagged Sites|Genetic Markers|*Human Chromosome|Physical Chromosome Mapping|Contig Mapping|*Chromosome Structures|Chromosomes, Artificial, Yeast|Polymerase Chain Reaction" 13 DNAJB5 10570961 Gene 1999 10.1016/s0378-1119(99)00333-9 3 1 0 67 "Humans|Animals|Mice|DNAJB1 protein, human|*HSP40 Heat-Shock Proteins|HSP70 Heat-Shock Proteins|Heat-Shock Proteins|HSC70 Heat-Shock Proteins|Introns|Heat Shock|Northern Blots|Base Sequence|Amino Acid Sequence|Exons|Carrier Proteins|DNA, Complementary|Cloning, Molecular|Conserved Sequence|Gene Expression Regulation|Sequence Homology, Amino Acid" 13 HYAL4 10493834 Genomics 1999 10.1006/geno.1999.5876 49 0 2 7 "Pregnancy|Male|Humans|Female|hyaluronidase PH-20|*Hyaluronoglucosaminidase|cDNA Libraries|*Chromosome Structures|cDNA|Exons|Amino Acid Sequence|Northern Blot|Cell Adhesion Molecules|PCR|Pseudogene|Sequence Homology, Amino Acid|Testis|*Chromosomes, Human|Hyal2 protein, human|GPI-Linked Proteins" 13 REG1P 10428955 EMBO J. 1999 PMC1171493 10.1093/emboj/18.15.4157 17 2 0 0 "*Saccharomyces cerevisiae|*Protein Phosphatase 1|*Hexokinase|*Proteome|Saccharomyces cerevisiae Proteins|*Yeast, Dried|Phosphorylation|Binding Protein|Protein-Serine-Threonine Kinases|Glucose|Binding Site|Mutations|Protein Binding" 13 BAIAP3 9790924 Biochem. Biophys. Res. Commun. 1998 10.1006/bbrc.1998.9408 13 1 0 29 "*C2 Domains|UNC13B protein, human|Nerve Tissue Proteins|*Protein Domain|Amino Acid Sequence|secretin receptor|*Receptors, G-Protein-Coupled|cDNA|Membrane Proteins|Cloning, Molecular|Sequence Homology, Amino Acid|Synaptotagmin|RNA, Messenger|Brain|Chromosome Mapping" 13 REG1P 9388294 Curr. Genet. 1998 10.1007/s002940050293 1 0 0 0 "*Saccharomyces cerevisiae|*Glucose|*B-DNA|Saccharomyces cerevisiae Proteins|Gene Expression Regulation, Fungal|Transcription Factors|DNA-Binding Proteins|DNA, Fungal|*Mitochondria|Genes, Fungal|Promoter Regions, Genetic|*Cell Nucleus|Repressor Proteins|Transcription, Genetic|Base Sequence|Trans-Activators|Reporter Gene|DNA Mutational Analysis" 13 SRRD 9628169 Psychiatry Clin. Neurosci. 1998 10.1111/j.1440-1819.1998.tb01048.x 0 0 0 66 "Adult|Humans|Female|*Sleep-Disordered Breathing|Polysomnography|Sleep Stages|Arousal|Respiratory Insufficiency|Positive-Pressure Respiration|Sleep|*Myopathy, Congenital|Oxygen|*Myopathy|Tracheostomy" 13 SRRD 9628167 Psychiatry Clin. Neurosci. 1998 10.1111/j.1440-1819.1998.tb01046.x 6 0 1 66 Male|Humans|Female|*Prevalence|*Inpatients|Sleep Apnea Syndromes|Polysomnography|Neuroleptics|Body Mass Index|Pulse Oximetries|Obesity|*Sleep Disorders|Risk Factors|Sex Factors|Schizophrenia 13 FKBP2 9286704 Genomics 1997 10.1006/geno.1997.4872 8 0 0 95 "*Multiple Endocrine Neoplasia Type 1|Cosmids|Chromosome Mapping|*Chromosome Structures|Polymorphism, Genetic|ESTs" 13 REG1P 8649403 Mol. Cell. Biol. 1996 PMC231286 10.1128/mcb.16.6.2922 36 4 2 0 "*Saccharomyces cerevisiae|SNF1-related protein kinases|*Binding Protein|*Protein-Serine-Threonine Kinases|Saccharomyces cerevisiae Proteins|Gene Expression Regulation, Fungal|Protein Phosphatase 1|Mutation|Glucose|Phosphorylation|Base Sequence|Phenotype|Cell Cycle" 13 SRRD 8872420 Dementia 1996 10.1159/000106893 1 0 0 66 Humans|Aged|Middle Aged|*Sleep|Sleep Disorders|*Movement Disorders|*Breathing|Cheyne-Stokes Respiration|Aging|*Health Status 13 FKBP2 7535744 Hum. Genet. 1995 10.1007/BF00208976 2 0 0 95 "*Multiple Endocrine Neoplasia Type 1|*Rapamycin|Chromosome Mapping|Genetic Linkage|Polymorphism, Single-Stranded Conformational|Genes, Tumor Suppressor|Cosmid|Exons|Loss of Heterozygosity|Polymerase Chain Reaction|Mutations|DNA, Neoplasm|Tacrolimus Binding Proteins" 13 REG1P 7862149 Mol. Cell. Biol. 1995 PMC230380 10.1128/mcb.15.3.1564 128 6 8 0 "*Saccharomyces cerevisiae|*Hexose Transporter|*Glucose|Saccharomyces cerevisiae Proteins|Gene Expression Regulation, Fungal|*Yeast, Dried|Genes, Fungal|DNA-Binding Proteins|Glucose Transport Proteins, Facilitative|Transcription Factors|Repressor Proteins|Membrane Proteins|Promoter Regions, Genetic|Mutations|HXK2 protein, S cerevisiae|Hexokinase" 13 REG1P 8013904 Genetics 1994 PMC1205907 21 2 0 0 "*Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Gene Expression Regulation, Fungal|Genes, Fungal|*Yeast, Dried|*Catabolite Repression|Genes, Suppressor|Mutation|Glucose|Repressor Proteins|Protein Kinase|HXK2 protein, S cerevisiae|Hexokinase" 13 FKBP2 7505249 Gene 1993 10.1016/0378-1119(93)90106-d 5 5 0 95 "Humans|Mice|Animals|FKBP-13|*FK506 Binding Protein|FK506|Carrier Proteins|Rapamycin|Base Sequence|Heat-Shock Proteins|Immunosuppressive Agents|DNA-Binding Proteins|Amino Acid Sequence|Peptidylprolyl Isomerase|Cloning, Molecular|DNA, Complementary|Intron|RNA, Messenger|Amino Acid Isomerases" 13 REG1P 8293971 Genetics 1993 PMC1205710 26 0 0 0 "*Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Gene Expression Regulation, Fungal|Genes, Fungal|Protein-Serine-Threonine Kinases|*Catabolite Repression|Repressor Proteins|Mutation|AMP-Activated Protein Kinases|Trans-Activators|Base Sequence|Glucose|Carrier Proteins|Amino Acid Sequence" 13 SRRD 8274086 Arq Neuropsiquiatr 1993 10.1590/s0004-282x1993000200014 0 0 0 66 Adult|Male|Humans|Middle Aged|Retrospective Studies|*Sleep|*Breathing|Polysomnography|Sleep Apnea Syndromes|Wakefulness|*Sleep Wake Disorders|Sleep Stages|Body Mass Index 13 SRRD 8217352 Eur. J. Cancer 1993 10.1016/0959-8049(93)90283-l 0 0 0 66 "Male|Humans|*Carboplatin|*Etoposide|*Neoplasms, Germ Cell and Embryonal|Testicular Neoplasms|Cisplatin|Antineoplastic Combined Chemotherapy Protocols|Remission Induction|Bleomycin|Neutropenia|Thrombocytopenia 3|Thrombocytopenia" 13 FKBP2 1281998 Biochem. Biophys. Res. Commun. 1992 10.1016/0006-291x(92)92276-4 0 0 0 95 "Humans|FKBP-13|*Tacrolimus Binding Protein 1A|In Situ Hybridization, Fluorescence|*Tacrolimus Binding Proteins|Chromosome Mapping|Base Sequence|Exons|Cloning, Molecular|Restriction Mapping|DNA|Chromosome Banding|Blotting, Southern|Introns|Amino Acid Sequence|Carrier Proteins|*Chromosome Structures" 13 glocose 2129136 Oral Microbiol. Immunol. 1990 10.1111/j.1399-302x.1990.tb00433.x 0 2 0 0 "*Streptococcus sanguis|*Prevotella intermedia|Streptococcus|Bacteroides|Culture Media|Colony Count, Microbial" 13 SRRD 6715805 J Gerontol 1984 10.1093/geronj/39.3.290 5 0 0 66 Middle Aged|Adult|Humans|Aged|Cross-Sectional Studies|*Sleep Wake Disorders|Sleep|*Dyssomnias|Polysomnographies|Sleep Apnea Syndromes|Respiration Disorders|Rapid Eye Movement|Periodicity 13 glocose 24258295 Planta 1983 10.1007/BF00392078 2 1 0 0 *Glucose|*3-O-Methylglucose|*Hexoses|*Cell Membrane|Biological Transport|*Binding Site|Kinetics|Methylglucosides|Active Transport|Mannitol|*Liverwort 13 glocose 6991732 JAMA 1980 2 0 0 0 "Humans|*Hyperglycemia|*Diabetes Mellitus|Insulin|Blood Glucose|Hypoglycemic Agents|Hyperglycemic Hyperosmolar Nonketotic Coma|Glucose|Insulin, Regular, Human|Postoperative Complications|Infusions, Parenteral" 13 glocose 588021 Q J Exp Physiol Cogn Med Sci 1977 10.1113/expphysiol.1977.sp002396 1 1 0 0 "Rats|Animals|*Phenformin|*Glucose|*Water|Intestinal Absorption|Intestine, Small|Intestinal Mucosa|Biological Transport|Perfusion|Biological Transport, Active|*Physical Phenomena|*Extracorporeal Circulation" 13 glocose 194380 Ukr Biokhim Zh 1977 0 5 0 0 "Animals|Glucokinase|Hexokinase|Phosphofructokinase-1|*Carbohydrate Metabolism|Glucose-6-Phosphatase|Insulin|Glucose 6 Phosphate Dehydrogenase|Pyruvate Kinase|Fructose-Bisphosphatase|*Cypriniformes|Insulin, Regular, Human" 13 glocose 156 Circ. 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Biol. 1975 0 0 0 0 "Humans|Adult|*Glucose Tolerance Test|dextrostix|*Glucose Oxidase|*Blood Glucose|Peroxidases|Reagent Strips|Diabetes Mellitus|Autoanalysis|Indicators and Reagents|Mass Screening|Biological Assay|Veins|Sugar|Diagnostic Tests, Routine|Research Design" 13 glocose 1101837 Arch Inst Cardiol Mex 1975 0 0 0 0 "Dogs|Animals|*Potassium|*Emetine|*Myocardium|Heart Rate|Heart|Glucose|Heart Ventricles|Insulin|Blood Pressure|Myocardial Contraction|Infusions, Parenteral" 13 ADGB 32084159 PLoS ONE 2020 PMC7034838 10.1371/journal.pone.0228722 1 0 0 6 12 AIFM3 32664187 Biomolecules 2020 10.3390/biom10071021 0 0 0 23 "Humans|*Apoptosis Inducing Factor|*Prognosis|*Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|Biomarkers, Tumor|*Mitochondrion|Kaplan-Meier Estimate|Lymphatic Metastasis" 12 AIFM3 32513270 Stem Cell Res Ther 2020 PMC7278138 10.1186/s13287-020-01737-0 0 0 0 23 "*Exosomes|*Myocardial Infarction|*Apoptosis|Mesenchymal Stem Cells|Mesenchymal Stem Cell Transplantation|Cardiomyocytes|MicroRNAs|Myocardium|*Hypoxia|Cells, Cultured" 12 ALKBH7 32510151 Gigascience 2020 PMC7276932 10.1093/gigascience/giaa059 0 0 0 15 Animals|*Chiroptera|*Diets|Feeding Behavior|*Genomics|Phylogeny|*Plant Leaves|*Nose 12 ALKBH7 31889914 Proteome Sci 2020 PMC6935500 10.1186/s12953-019-0156-x 0 0 0 15 "Male|*Proteomics|Protein, Mitochondrial|*Cell Lines|Necrosis|Apoptosis|Mitochondria" 12 ANKRD30A 32558282 Proteomics Clin Appl 2020 10.1002/prca.202000007 0 0 0 4 "*Computational Biology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|RNA, Messenger" 12 C15orf41 32518175 J. Med. Genet. 2020 10.1136/jmedgenet-2020-106880 0 0 0 29 "*Anemia, Dyserythropoietic, Congenital|*Prevalence|Nuclear Proteins|Glycoproteins|Mutation|Gene Expression" 12 C15orf41 32293259 BMC Mol Cell Biol 2020 PMC7092493 10.1186/s12860-020-00258-1 0 0 0 29 "*Anemia, Dyserythropoietic, Congenital|Nuclear Proteins|Glycoproteins|Phenotype|Mutations|*Transcription Factors|*Genes, Regulator|Chromatin|Heterochromatin" 12 C15orf41 32239177 Biochem. J. 2020 PMC7261414 10.1042/BCJ20190944 0 0 0 29 "Humans|*Anemia, Dyserythropoietic, Congenital|Nuclear Proteins|Mutations|Glycoproteins|Histone|Erythroblasts|*Genes, Regulator|*Transcription Factors|Chromatin|Heterochromatin" 12 C6orf106 32607230 J Anim Sci Biotechnol 2020 PMC7318453 10.1186/s40104-020-00469-8 0 0 0 80 Male|Animals|*Chickens|Genome-Wide Association Study|*Phenotype|Animal Feed|Quantitative Trait Loci|Eating 12 C6orf106 32518853 Heliyon 2020 PMC7270589 10.1016/j.heliyon.2020.e04115 0 0 0 80 "Humans|*Cytokines|Immunity, Innate|Signal Transduction|Gene Expression Regulation|Tumor Necrosis Factor-alpha|Inflammation|Type I Interferon|ILRUN protein, human|Neoplasm Proteins|*Anti-Infective Agents|Antiviral Agents|*Anti-Bacterial Agents|Protein Binding" 12 DNAH8 32619401 Am. J. Hum. Genet. 2020 10.1016/j.ajhg.2020.06.004 0 0 0 24 "Humans|Male|Female|Pregnancy|Mice|Animals|*Sperm Flagellum|Infertility, Male|Spermatozoa|*Alleles|Teratozoospermia, Astheno|Sequencing, Whole Exome|Homozygote|*Azoospermia|Flagella|Exome|Sperm Injections, Intracytoplasmic|Testis|Phenotypes|Cytoskeletal Proteins|Mutation|*Multiple Abnormalities|Mice, Knockout|France" 12 FAM135B 32639949 Aging (Albany NY) 2020 10.18632/aging.103115 0 0 0 6 "Melanoma, Cutaneous Malignant|*Melanoma|*Skin Neoplasms|*Epigenomics|*Transcriptome|DNA Copy Number Variations|*Genomics|DNA Methylation|Gene Expression Regulation, Neoplastic|Prognosis|Transcriptome Analysis|Disease Progression|Downregulation|Genes, Regulator" 12 FAM135B 32194665 Oncol Lett 2020 PMC7039107 10.3892/ol.2020.11272 0 0 0 6 "*Esophageal Cancer|Esophageal Squamous Cell Carcinoma|*Esophageal Mucosa|Carcinoma, Squamous Cell|Lymphatic Metastasis|Immunohistochemistry|Prognosis|Biomarkers, Tumor|Epithelium|Carcinoma in Situ|Esophagus|Carcinogenesis|Disease Progression|*Metalloproteases" 12 FGD6 32678081 Nat Commun 2020 10.1038/s41467-020-17312-3 0 0 0 74 "Humans|Genome-Wide Association Study|*Aging|Longevity|Genome|Genomics|*Biochemical Phenomena|Phenotypes|DNA Damage|Homeostasis|Heme|SLC4A7 protein, human|Sodium-Bicarbonate Symporters" 12 FGD6 32442411 Am. J. Hum. Genet. 2020 PMC7273528 10.1016/j.ajhg.2020.04.008 0 0 0 74 "Male|Female|Humans|*Endothelial Cells|*Regulatory Sequences, Nucleic Acid|Quantitative Trait Loci|Genetic Predisposition|SNPs|Genome-Wide Association Study|*Traits, Complex|Allele|Promoter Regions, Genetic|Chromatin|Genomics|Phenotypes|Coronary Artery Disease|Transcriptomes|*Endothelium" 12 FGD6 32195675 Asia Pac J Ophthalmol (Phila) 2020 10.1097/01.APO.0000656976.47696.7d 0 0 0 74 "Humans|Aged|Genome-Wide Association Study|Angiogenesis Inhibitors|Vascular Endothelial Growth Factor A|Visual Acuity|Wet Macular Degeneration|Choroidal Neovascularization|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Linkage Disequilibrium|Genotype|Asian Continental Ancestry Group|SKIV2L protein, human|DNA Helicases|Case-Control Studies|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1" 12 GAS2L1 32289147 J. Cell Biol. 2020 PMC7199859 10.1083/jcb.201909094 0 0 0 61 "Humans|*Phosphorylation|*Centrosome|Mitosis|NIMA-Related Kinases|Chromosome Segregation|Cell Cycle Proteins|Microtubules|Protein-Serine-Threonine Kinases|F-actin-binding proteins|Microfilament Proteins|calponin|Cytoskeletal Proteins|HeLa Cells|F-Actin|HEK293 Cells|Calcium-Binding Proteins|GAS2L1 protein, human|NEK2 protein, human" 12 HCG11 32433496 Sci Rep 2020 PMC7239855 10.1038/s41598-020-65421-2 0 0 0 0 "Humans|Female|*RNA, Long Noncoding|*Mitogen-Activated Protein Kinase 14|Gene Expression Regulation, Neoplastic|MicroRNAs|Biomarkers, Tumor|Up-Regulation|*Cancer" 12 HCG11 32397815 DNA Cell Biol. 2020 10.1089/dna.2019.5313 0 0 0 0 "Humans|Female|RNA, Long Noncoding|Prognosis|Gene Expression Regulation, Neoplastic|*Carcinoma, Endometrioid|Endometrial Neoplasms|Biomarkers, Tumor|Sequencing, RNA|Gene Expression Profiling|Kaplan-Meier Estimate|Transcriptome|DNA Methylation|Databases, Genetic|Nomogram|Receiver Operating Characteristic|Cohort Studies" 12 HCG11 32271435 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202003_20684 0 0 0 0 "*RNA, Long Noncoding|MicroRNAs|Cell Proliferation|*Disease Progression|Cell Movement|Gene Expression Regulation, Neoplastic|Apoptosis|*Laryngeal Neoplasms|Down-Regulation|Cell Line, Tumor" 12 HCG11 32099468 Cancer Manag Res 2020 PMC7002755 10.2147/CMAR.S231796 0 0 0 0 "Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Prognosis|Neoplasm Recurrence, Local|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Gene Regulatory Networks|Kaplan-Meier Estimate" 12 HCG11 31889902 Cancer Cell Int. 2020 PMC6933929 10.1186/s12935-019-1046-0 0 0 0 0 "*RNA, Long Noncoding|*Stomach Neoplasms|*Wnt Signaling Pathway|CTNNB1 protein, human|*beta Catenin|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Apoptosis|Disease Progression" 12 hcg18 32663252 J. Biochem. 2020 10.1093/jb/mvaa073 0 0 0 0 "Animals|*Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Hep G2 Cells|Apoptosis|Cell Line, Tumor|*Disease Progression|Messenger RNA" 12 hcg18 32559619 Biomed. Pharmacother. 2020 10.1016/j.biopha.2020.110217 0 0 0 0 "Humans|*Lung Adenocarcinoma|Cell Proliferation|*Disease Progression|MicroRNAs|Lung Cancer|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Adenocarcinoma|Up-Regulation|Apoptosis|Cell Movement|Cell Cycle|Oncogene|Cell Line, Tumor|Carcinogenesis|Lung" 12 hcg18 32449112 Hum. Cell 2020 10.1007/s13577-020-00366-2 0 0 0 0 "Humans|*RNA, Long Noncoding|*Muscle, Smooth, Vascular|Myocytes, Smooth Muscle|PDGF-BB|Cell Proliferation|*Phenotypes|Cell Movement|RNA Interference|Cells, Cultured|shRNA|Apoptosis" 12 hcg18 32257949 Front Oncol 2020 PMC7092636 10.3389/fonc.2020.00340 0 0 0 0 "Humans|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*mRNA|*Liver Neoplasms|MIRN195 microRNA, human|*miRNA|*Prognosis|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Upregulation|CHEK1 protein, human|Checkpoint Kinase 1|MIRN497 microRNA, human" 12 hcg18 32256081 Onco Targets Ther 2020 PMC7092690 10.2147/OTT.S240965 0 0 0 0 "*RNA, Long Noncoding|*Stomach Neoplasms|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Tumorigenesis|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction|Prognosis|Cell Movement|Apoptosis|Up-Regulation|Cell Line, Tumor|*Protein Kinase Inhibitors" 12 hcg18 32663252 J. Biochem. 2020 10.1093/jb/mvaa073 0 0 0 0 "Animals|*Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Hep G2 Cells|Apoptosis|Cell Line, Tumor|*Disease Progression|Messenger RNA" 12 hcg18 32559619 Biomed. Pharmacother. 2020 10.1016/j.biopha.2020.110217 0 0 0 0 "Humans|*Lung Adenocarcinoma|Cell Proliferation|*Disease Progression|MicroRNAs|Lung Cancer|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Adenocarcinoma|Up-Regulation|Apoptosis|Cell Movement|Cell Cycle|Oncogene|Cell Line, Tumor|Carcinogenesis|Lung" 12 hcg18 32449112 Hum. Cell 2020 10.1007/s13577-020-00366-2 0 0 0 0 "Humans|*RNA, Long Noncoding|*Muscle, Smooth, Vascular|Myocytes, Smooth Muscle|PDGF-BB|Cell Proliferation|*Phenotypes|Cell Movement|RNA Interference|Cells, Cultured|shRNA|Apoptosis" 12 hcg18 32257949 Front Oncol 2020 PMC7092636 10.3389/fonc.2020.00340 0 0 0 0 "Humans|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*mRNA|*Liver Neoplasms|MIRN195 microRNA, human|*miRNA|*Prognosis|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Upregulation|CHEK1 protein, human|Checkpoint Kinase 1|MIRN497 microRNA, human" 12 hcg18 32256081 Onco Targets Ther 2020 PMC7092690 10.2147/OTT.S240965 0 0 0 0 "*RNA, Long Noncoding|*Stomach Neoplasms|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Tumorigenesis|*Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Cell Proliferation|Signal Transduction|Prognosis|Cell Movement|Apoptosis|Up-Regulation|Cell Line, Tumor|*Protein Kinase Inhibitors" 12 IRF2BPL 32657892 Curr. Opin. Neurol. 2020 10.1097/WCO.0000000000000831 0 0 0 58 "Humans|*Dystonic Disorders|*Dystonia|Phenotype|Genetic Testing|Mutation|Sequencing, Next-Generation|Neurologist|Bewilderment" 12 IRF2BPL 32520805 Curr. Opin. Neurol. 2020 10.1097/WCO.0000000000000831 0 0 0 58 "Humans|*Dystonic Disorders|*Dystonia|Phenotype|Genetic Testing|Mutation|Sequencing, Next-Generation|Neurologist|Bewilderment" 12 IRF2BPL 32427350 Epilepsia 2020 10.1111/epi.16533 0 0 0 58 Child|Adult|Humans|*Genetic Testing|*Epilepsy|Genetic Predisposition to Disease|Mutation|*Organizations 12 KIAA1324 32412912 Aging (Albany NY) 2020 PMC7288931 10.18632/aging.103202 0 0 0 54 "Humans|Female|*Epigenesis, Genetic|*Genomics|*Endometrial Cancer|DNA Methylation|DNA Copy Number Variations|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiles|Prognosis|Mutations|Cell Line, Tumor|Tumor Microenvironment" 12 LRIT3 31959619 eNeuro 2020 PMC7031853 10.1523/ENEURO.0002-20.2020 1 0 0 31 "Male|Female|Mice|Animals|*Retina|Retinal Bipolar Cells|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|*Signal Transduction|Retinal Ganglion Cells|Synapse|Dendrites|TRPM Cation Channels|Glutamate|Lrit3 protein, mouse|Membrane Proteins|nyctalopin protein, mouse|Proteoglycans" 12 MS4A12 32462020 Biomed Res Int 2020 PMC7232680 10.1155/2020/8082697 0 0 0 16 "*Colorectal Cancer|Gene Ontology|Protein Interaction Maps|Bioinformatics|Gene Regulatory Networks|Databases, Genetic|Gene Expression Profiles|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Signal Transduction|*Colonic Neoplasms|Software|Upregulation|Genes, Regulator" 12 OTUD6B 32328410 Adv Sci (Weinh) 2020 PMC7175249 10.1002/advs.201902040 0 0 0 43 "*Carcinoma, Hepatocellular|*Liver Neoplasms|VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|Transcription Factors|Carcinoma, Renal Cell|DNA-Binding Proteins|Ubiquitylation|Ligases|Protein Binding|Cell Line, Tumor|Kidney Neoplasms" 12 OTUD6B 32256450 Front Endocrinol (Lausanne) 2020 PMC7089936 10.3389/fendo.2020.00136 0 0 0 43 12 PRAP1 32629119 Cell Mol Gastroenterol Hepatol 2020 10.1016/j.jcmgh.2020.06.011 0 0 0 55 Mice|Animals|Lactobacillus rhamnosus|*Epithelium|Intestinal Epithelium|Intestines|Probiotic|Colon|*Protective Agents|Apoptosis|*Cell Death|*Digestive System|Proline 12 RASL11A 32554701 Genetics 2020 10.1534/genetics.120.303428 0 0 0 8 "Humans|Animals|*Marsupialia|*Neoplasm Regression, Spontaneous|Facial Neoplasms" 12 RASL11A 32444848 Sci Rep 2020 PMC7244564 10.1038/s41598-020-65584-y 0 0 0 8 *Perceptron|*Proteins|Machine Learning|*Neoplastic Processes|*Immunotherapy|Amino Acid Sequence|Cancer|Receiver Operating Characteristics|RNA 12 RBM19 31913546 Anim. Genet. 2020 10.1111/age.12901 0 0 0 63 "Cattle|Animals|Female|*Milk|*Genotype|Dairying|Lactation|Breeding|Phenotype|SNPs|*Cholesterol|Models, Genetic|Genome|Genomics" 12 serpinb11 32503295 Cancers (Basel) 2020 10.3390/cancers12061459 0 0 0 15 "Humans|Female|*Carcinoma, Ovarian Epithelial|eupatilin|Phosphatidylinositol 3-Kinases|*Flavonoids|*Mitochondria|*Endoplasmic Reticulum|*Ovarian Cancer|Mitogen-Activated Protein Kinases|*Cell Death|Apoptosis|*Calcium, Dietary|Epithelial Cells|Cell Cycle Arrest|Cell Line, Tumor" 12 SLC25A43 32485717 Cytogenet. Genome Res. 2020 10.1159/000508050 0 0 0 49 "Child|Male|Female|Pregnancy|Humans|*Mothers|*Syndrome|X Chromosome Inactivation|Chromosomes, Human, X|Mental Retardation, X-Linked|Intellectual Disability|Chromosome Deletion|*Ubiquitin-Conjugating Enzymes|*Abortion, Habitual|*Phenotypes|Pedigree|*Chromosome Structures|NKRF protein, human|Repressor Proteins|SLC25A43 protein, human|Tumor Suppressor Proteins" 12 SLC25A43 32272554 Cancers (Basel) 2020 PMC7226056 10.3390/cancers12040892 0 0 0 49 "Humans|*Glioma|*RNA-Binding Proteins|Gene Ontology Project|Glioblastoma|Brain Neoplasms|Protein Interaction Maps|RNA|Gene Regulatory Networks|Gene Expression Profiling|Computational Biology|Sequencing, RNA|Gene Expression Regulation, Neoplastic|Transcriptome|Genome" 12 SLC43A3 32339528 J Pharm Sci 2020 10.1016/j.xphs.2020.04.013 0 0 0 81 "Humans|*Biological Transport|Equilibrative Nucleoside Transporter 1|Hypoxanthine|Purines|Endothelial Cells|Hepatocytes|Adenine|SLC43A3 protein, human|Amino Acid Transport Systems" 12 SLC43A3 32217606 J. Lipid Res. 2020 PMC7193958 10.1194/jlr.RA119000294 0 0 0 81 "Humans|Mice|Animals|Adipocytes|*Fatty Acids, Nonesterified|Adipose Tissue|Carrier Proteins|Obesity|Transporters, Membrane|Biological Transport|Cell Differentiation|Membrane Proteins|RNA, Messenger|SLC43A3 protein, human|Amino Acid Transport Systems" 12 SLC43A3 31948943 Cancer Res. 2020 PMC7056593 10.1158/0008-5472.CAN-19-2257 0 0 0 81 "Humans|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Telomerase|Thionucleosides|Deoxyguanosine|DNA Damage|Cell Line, Tumor|Nucleosides|Biological Transport|Transporters, Membrane" 12 SNORD44 32606371 Sci Rep 2020 PMC7326970 10.1038/s41598-020-67446-z 0 0 0 0 "*RNA, Small Nucleolar|*Osteoarthritis|Articular Cartilage|Chondrocytes|Fluid, Synovial|Gene Expression|Gene Expression Profiling|Interleukin 1" 12 SNORD44 32062699 Histochem. Cell Biol. 2020 10.1007/s00418-020-01848-y 0 0 0 0 "Animals|Mice|*RNA, Small Nucleolar|Mice, Nude|*Glioma|*Apoptosis|Cell Proliferation|Cell Migration|Neoplasm Invasiveness|RNA, Long Noncoding|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|Downregulation|Signal Transduction|Xenograft Model Antitumor Assays|Up-Regulation|Matrix Metalloproteinase 9" 12 TASP1 32071545 Int. J. Biol. Sci. 2020 PMC7019140 10.7150/ijbs.40516 0 0 0 65 "Humans|*Gallbladder Neoplasms|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Cell Proliferation|*Up-Regulation|Signal Transduction|Cell Movement|Cell Line, Tumor|*Neoplastic Processes|*Transcriptional Activation" 12 TASP1 32064513 Nucleic Acids Res. 2020 PMC7144948 10.1093/nar/gkaa096 0 0 0 65 "Humans|*Catalytic Domain|*Proteolysis|*DNA-Directed DNA Polymerase|DNA Replication|DNA Repair|DNA Damage|*Ubiquitination|Mutations|DNA-Binding Proteins|Stability, Genome|DNA|Cell Line|REV3L protein, human" 12 TMEM33 32614325 Elife 2020 PMC7332293 10.7554/eLife.57306 0 0 0 152 "Proteomics|*Endoplasmic Reticulum|UBB protein, human|*Ubiquitin|Endoplasmic Reticulum-Associated Degradation|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Ubiquitination|Ubiquitin-Protein Ligases|*Signal Transduction|Cytosol|Immunity, Innate" 12 TMEM33 32429378 Life (Basel) 2020 PMC7281126 10.3390/life10050068 0 0 0 152 Pregnancy|Swine|Animals|Female|*Endometrium|Embryo Implantation|Transcriptome|Gene Expression Profiling|Gene Regulatory Networks|Sus scrofa|Uterus 12 xpo7 32245436 BMC Psychiatry 2020 PMC7118970 10.1186/s12888-020-02540-0 0 0 0 135 "*Bipolar Disorder|*Depressive Disorder, Major|Prevalences" 12 ZPBP 31985809 Hum. Reprod. 2020 PMC6993856 10.1093/humrep/dez246 0 0 0 18 "Male|Humans|*Teratozoospermia|*Exome|*Whole Exome Sequencing|Infertility, Male|Spermatozoa|Point Mutation|Alleles|Gene Deletion|Membrane Proteins" 12 ACTL7A 31310081 Int J Fertil Steril 2019 PMC6642428 10.22074/ijfs.2019.5702 0 0 0 4 "Humans|Male|Mice|Animals|*Actins|Japan|*Spermatogenesis|Infertility, Male|Testis|Polymorphism, Single Nucleotide|ACTL7A protein, human" 12 AIFM3 31827401 Cancer Cell Int. 2019 PMC6892182 10.1186/s12935-019-1052-2 2 0 0 23 "*RNA, Long Noncoding|*miRNA|*Urinary Bladder|*Urinary Bladder Neoplasms|Gene Regulatory Networks|RNA, Messenger|Gene Expression Regulation, Neoplastic|Gene Ontology|Prognosis|Biomarkers, Tumor|*Carcinoma, Transitional Cell|Kaplan-Meier Estimate" 12 AIFM3 31088422 BMC Cancer 2019 PMC6518782 10.1186/s12885-019-5659-4 2 1 0 23 "Humans|*Prognosis|Disease-Free Survival|Biomarkers, Tumor|Lymphatic Metastasis|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Neoplasm Staging" 12 AIFM3 30614210 Mol Genet Genomic Med 2019 PMC6393688 10.1002/mgg3.507 4 0 0 23 "Humans|Chromosome 22q11.2 Microduplication Syndrome|*Autism Spectrum Disorder|*Penetrance|Chromosome Duplication|DiGeorge Syndrome|Abnormalities, Multiple|*Phenotypes|Low-Copy Repeats|Chromosomes, Human, Pair 22" 12 ALKBH7 31434717 J. Cell. Sci. 2019 10.1242/jcs.223891 0 0 0 15 "Humans|*RNA, Mitochondrial|*Mitochondria|*Oxidation-Reduction|tRNA|2-Oxoglutarate|DNA|ALKBH1 protein, human|AlkB Homolog 1, Histone H2a Dioxygenase" 12 ALKBH7 31036064 Cancer Commun (Lond) 2019 PMC6489267 10.1186/s40880-019-0369-5 4 0 0 15 "*Prognosis|*Cancer|*Ketoglutaric Acids|*Cell Adhesion|*Oxygenases|Gene Expression Profiling|Tumor Hypoxia|*Cell Cycle Checkpoints|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers, Tumor" 12 ANKRD30A 31632087 Onco Targets Ther 2019 PMC6792947 10.2147/OTT.S215898 0 1 0 4 "Humans|*Triple-Negative Breast Cancer|*Prognosis|*Computational Biology|*Data Analysis|Receptor, ErbB-2|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Kaplan-Meier Estimate" 12 C15orf41 31191338 Front Physiol 2019 PMC6539198 10.3389/fphys.2019.00621 1 0 0 29 "*Anemia, Dyserythropoietic, Congenital|Nuclear Proteins|Mutation" 12 C15orf41 30836435 Br. J. Haematol. 2019 PMC6519365 10.1111/bjh.15817 2 0 0 29 "Humans|*Anemia, Dyserythropoietic, Congenital|Mutations|Alleles|Iron Overload|Nuclear Proteins|Glycoproteins|Bone Marrow" 12 C6orf106 30677029 PLoS Genet. 2019 PMC6345421 10.1371/journal.pgen.1007603 5 0 0 80 "Humans|*Thinness|*Obesity, Morbid|Genome-Wide Association Study|Obesity|Body Mass Index|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Gene Frequency" 12 DNAH8 31178125 Am. J. Hum. Genet. 2019 PMC6612517 10.1016/j.ajhg.2019.04.015 4 0 0 24 "Male|Humans|*Asthenozoospermia|DNAH9 protein, human|Axonemal Dyneins|Axoneme|*Infertility, Male|Kartagener Syndrome|*Sperm|Cilia|Sperm Flagellum|*Mutations|Flagella|Phenotype|Pedigree|Proteins|Alleles|Tubulin" 12 DNAH8 30981109 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.108856 1 0 0 24 "Humans|*Carcinoma, Hepatocellular|*Transcriptome|*Liver Neoplasms|*Proteomics|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease-Free Survival|*Genomics|Gene Expression Profiling|Up-Regulation|Kaplan-Meier Estimate|Sequencing, RNA|Cell Cycle|RNA, Messenger|Mutation|Whole Exome Sequencing" 12 FAM135B 31612912 Jpn. J. Clin. Oncol. 2019 10.1093/jjco/hyz131 1 0 0 6 "Humans|*Prognosis|*Small Cell Lung Carcinoma|Lung Cancer|*Mutations|*Genomics|*Chinese|Biomarkers, Tumor" 12 FAM135B 31561612 Animals (Basel) 2019 PMC6826494 10.3390/ani9100732 1 0 0 6 Pregnancy|Female|Swine|Animals|*Genome-Wide Association Study|Litter Size|*Reproduction|*Phenotype|Quantitative Trait Loci|Single Nucleotide Polymorphism|Genotype|Weaning|Birth Weight|Body Weight|Birth 12 FAM135B 31199602 Cancer Med 2019 PMC6675718 10.1002/cam4.2199 3 0 0 6 Humans|*Small Cell Lung Carcinoma|Lung Cancers|*Chinese|Mutation|*Genetic Profile|Tumor Suppressor Protein p53|Genomics 12 GAS2L1 31486213 EMBO Rep. 2019 PMC6831992 10.15252/embr.201947732 2 3 0 61 Animals|Rats|*Actins|*Axons|Microtubules|Actin Cytoskeleton|Neurons|Microtubule-Associated Proteins|Cytoskeleton|Tubulin|Microfilament Proteins|Hippocampus|Protein Binding 12 HCG11 31858580 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201912_19771 0 0 0 0 "*Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|*Disease Progression|Cell Proliferation|Hep G2 Cells|Apoptosis|Cell Line, Tumor|Signal Transduction" 12 HCG11 31310044 Cell Prolif. 2019 PMC6797506 10.1111/cpr.12615 7 5 0 0 "Humans|*RNA, Long Noncoding|*Glioma|CPEB3 protein, human|*RNA-Binding Proteins|Antagomirs|MicroRNAs|Brain Neoplasms|Cell Proliferation|*Disease Progression|RNA Interference|RNA, Small Interfering|Cell Movement|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|Up-Regulation" 12 HCG11 31228307 Cell Biol. Int. 2019 10.1002/cbin.11194 3 4 0 0 "Humans|Male|Mice|Animals|*RNA, Long Noncoding|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|MTOR protein, human|*TOR Serine-Threonine Kinases|Cell Proliferation|RNA, Micro|Signal Transduction|*Prostate Cancer|Phosphoinositide 3 Kinase|Neoplasm Invasiveness|Apoptosis|Cell Movement|*Disease Progression|Carcinoma, Non-Small-Cell Lung|Gene Expression Regulation, Neoplastic|Cell Cycle|Cell Line, Tumor" 12 HCG11 30706982 J Gene Med 2019 10.1002/jgm.3074 1 1 0 0 "Humans|Adult|*RNA, Long Noncoding|*Glioma|Brain Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Up-Regulation|Apoptosis|Disease Progression|Cell Transformation, Neoplastic|MTA3 protein, human|Neoplasm Proteins" 12 hcg18 31854468 Clin. Exp. Pharmacol. Physiol. 2019 10.1111/1440-1681.13230 1 0 0 0 "Humans|*RNA, Long Noncoding|*Colorectal Cancer|MicroRNAs|Wnt Signaling Pathway|Tumorigenesis|Cell Proliferation|*Upregulation|RNA Interference|Gene Expression Regulation, Neoplastic|*Catenins|Cell Movement|beta Catenin|3' Untranslated Regions|Down-Regulation|Cell Line, Tumor|Oncogenes|*Transcriptional Activation|*Colonic Neoplasms" 12 hcg18 31841193 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201912_19678 0 0 0 0 "*RNA, Long Noncoding|*Nasopharyngeal Carcinoma|*Hedgehog Proteins|CCND1 protein, human|*Cyclin D1|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|MicroRNAs|Wnt Signaling Pathway|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Prognosis|Apoptosis|Nasopharyngeal Neoplasms" 12 hcg18 31676691 J. Rheumatol. 2019 10.3899/jrheum.190376 0 2 0 0 "Humans|hydrogen sulfite|*Sulfites|Rheumatoid Arthritis|Autoantibodies|DNA Methylation|Peptides, Cyclic|Genome-Wide Association Study|Polymorphism, Genetic" 12 hcg18 31854468 Clin. Exp. Pharmacol. Physiol. 2019 10.1111/1440-1681.13230 1 0 0 0 "Humans|*RNA, Long Noncoding|*Colorectal Cancer|MicroRNAs|Wnt Signaling Pathway|Tumorigenesis|Cell Proliferation|*Upregulation|RNA Interference|Gene Expression Regulation, Neoplastic|*Catenins|Cell Movement|beta Catenin|3' Untranslated Regions|Down-Regulation|Cell Line, Tumor|Oncogenes|*Transcriptional Activation|*Colonic Neoplasms" 12 hcg18 31841193 Eur Rev Med Pharmacol Sci 2019 10.26355/eurrev_201912_19678 0 0 0 0 "*RNA, Long Noncoding|*Nasopharyngeal Carcinoma|*Hedgehog Proteins|CCND1 protein, human|*Cyclin D1|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|MicroRNAs|Wnt Signaling Pathway|Epithelial-Mesenchymal Transition|Cell Line, Tumor|Prognosis|Apoptosis|Nasopharyngeal Neoplasms" 12 hcg18 31676691 J. Rheumatol. 2019 10.3899/jrheum.190376 0 2 0 0 "Humans|hydrogen sulfite|*Sulfites|Rheumatoid Arthritis|Autoantibodies|DNA Methylation|Peptides, Cyclic|Genome-Wide Association Study|Polymorphism, Genetic" 12 IRF2BPL 31583567 Mol. Biol. Rep. 2019 10.1007/s11033-019-05109-7 0 0 0 58 Child|Humans|Female|Lysosomal Storage Diseases|*Lysosomes|Heterozygote|Epilepsy|*Endosomes|Mutation|Skin 12 IRF2BPL 31432588 Am. J. Med. Genet. A 2019 10.1002/ajmg.a.61328 0 0 0 58 Humans|*Phenotypes|Infantile Spasms|*Mutation|Epilepsy|Lennox Gastaut Syndrome|Nuclear Proteins|Carrier Proteins|Central Nervous System 12 IRF2BPL 31022319 J. Leukoc. Biol. 2019 10.1002/JLB.MR1218-507R 4 0 0 58 Transcription Factors|DNA-Binding Proteins|Nuclear Protein|Transcriptional Activation|Carrier Proteins|Isoforms|Apoptosis|Lymphocyte Activation|Cell Line|Macrophage|*Homeostasis 12 KIAA1324 30979743 Clin. Cancer Res. 2019 10.1158/1078-0432.CCR-18-3818 3 0 0 54 "Humans|Female|*Proteomics|*Cystadenocarcinoma, Serous|*Ovarian Neoplasms|Carcinoma, Endometrioid|Adenocarcinoma, Clear Cell|Biomarkers, Tumor|Tumor Suppressor Protein p53|Neoplasm Proteins|*Endometrium" 12 LRIT3 31578364 Sci Rep 2019 PMC6775105 10.1038/s41598-019-50573-7 2 0 0 31 "Humans|Dogs|Animals|Night blindness, congenital stationary|*Genome-Wide Association Study|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|Retina|Electroretinography|Retinal Cone Photoreceptor Cells|Pedigree|*Sequencing, Whole Genome|Mutation|Membrane Proteins|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate" 12 LRIT3 31189098 Cell Rep 2019 PMC6628893 10.1016/j.celrep.2019.05.056 4 0 0 31 "Night Blindness|Retinal Bipolar Cells|Eye Diseases, Hereditary|Retina|Genetic Diseases, X-Linked|Rod Photoreceptors|*Signal Transduction|Synapse|Myopia|Dendrites|Receptors, Metabotropic Glutamate|TRPM Cation Channels|Membrane Proteins|Glutamates" 12 LZIC 31432149 Int. 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Biol. Rep. 2019 10.1007/s11033-019-05214-7 2 0 0 54 "Mice|Animals|*Clustered Regularly Interspaced Short Palindromic Repeats|*CRISPR-Cas Systems|RNA, Guide|Gene Editing|Gene Targeting|Gene Knock-In Techniques|Knockout Mouse|Endonucleases|Zygotes|Integrases|C57BL Mouse" 12 NOMO1 31520489 Genet. Epidemiol. 2019 10.1002/gepi.22260 0 0 0 54 "Humans|*DNA Copy Number Variations|Sequencing, Whole Genome|Genome, Human|Genome-Wide Association Study|Genomics|Polymorphism, Single Nucleotide|glutathione S-transferase M1|Glutathione Transferase|Gene Deletions" 12 OTUD6B 31462944 EPMA J 2019 PMC6695468 10.1007/s13167-019-00175-0 7 3 0 43 "Humans|Female|*RNA, Long Noncoding|*mRNA|*Precision Medicine|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|Gene Modules|Prognosis|MicroRNAs|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Kaplan-Meier Estimate" 12 OTUD6B 31310629 PLoS ONE 2019 PMC6634788 10.1371/journal.pone.0218989 1 0 0 43 "Humans|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms|Prognosis|Carcinoma, Squamous Cell|Cancer, Tongue|Papillomavirus Infections|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|EPS8 protein, human|Adaptor Proteins, Signal Transducing|FNDC1 protein, human|Neoplasm Proteins|UBE2Q1 protein, human|Ubiquitin-Conjugating Enzymes|SLC4A1AP protein, human|Antiporters" 12 OTUD6B 31156645 Front Immunol 2019 PMC6533854 10.3389/fimmu.2019.01100 0 3 0 43 "Humans|*Apoptosis|Long Non-Coding RNA|*Sclerosis, Systemic|Cell Proliferation|CCND1 protein, human|Cyclin D1|Downregulation|Smooth Muscle Cells|Fibrosis|Fibroblasts|mRNA|Extracellular Matrix|CASP3 protein, human|Caspase 3|Platelet-Derived Growth Factor" 12 OTUD6B 31126858 Vaccine 2019 PMC7087478 10.1016/j.vaccine.2019.05.024 0 2 0 43 "Humans|Female|Mice|Animals|*Mammary Neoplasms, Animal|*Antigens, Neoplasm|Cancer Vaccines|Receptor, ErbB-2|Mice, Transgenic|Mammary Neoplasms, Experimental|Triple-Negative Breast Cancer|SWAP70 protein, human|DNA-Binding Proteins|Nuclear Proteins|Minor Histocompatibility Antigens|Guanine Nucleotide Exchange Factors|Swap70 protein, mouse" 12 OTUD6B 30670025 Mol. Cancer 2019 PMC6341572 10.1186/s12943-019-0942-1 0 7 0 43 "*RNA, Long Noncoding|*Carcinoma, Renal Cell|*Wnt Signaling Pathway|Gene Expression Regulation, Neoplastic|Cell Proliferation|beta Catenin|Cell Movement|*Catenins|Cell Line, Tumor|Epithelial-Mesenchymal Transition|Carcinogenesis|Downregulation|Apoptosis|Kidney Neoplasms|Prognosis" 12 PRAP1 31660454 Dev Reprod 2019 PMC6812973 10.12717/DR.2019.23.3.277 0 4 0 55 "Pregnancy|Female|Mice|Animals|*Uterus|ARID1A protein, human|*Nuclear Proteins|*Transcription Factors|Implantation, Embryo|Receptors, Progesterone|Progesterone|Estradiol|Proline|Arid1a protein, mouse|DNA-Binding Proteins" 12 PRAP1 31558421 Ann Hepatol 2019 10.1016/j.aohep.2019.05.010 0 4 0 55 "*Liver Regeneration|Cell Proliferation|MicroRNAs|Down-Regulation|Cell Movement|Signal Transduction|Cell Line, Tumor|Apoptosis|Proline" 12 RASL11A 31633244 J. Cell. Biochem. 2019 10.1002/jcb.29425 0 0 0 8 "*Transcriptome|*Glioblastoma|*Data Analysis|*Transcriptome Analysis|Gene Regulatory Networks|Gene Ontology|Computational Biology|Gene Expression Regulation, Neoplastic|Protein Interaction Maps|MicroRNAs|Biomarkers, Tumor|*Genetic Screening" 12 RASL11A 31174021 Neoplasia 2019 PMC6551473 10.1016/j.neo.2019.04.009 2 1 0 8 "Humans|*Transcriptome|*Aneuploidy|*Chromosomes B|Colorectal Cancer|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|DNA Copy Number Variations|Up-Regulation|Genomics|Transcriptional Activation|Diploid Cell|Cell Line, Tumor|Genes, cdc|SPG20 protein, human|MAB21L1 protein, human|Homeodomain Proteins|DCLK1 protein, human|Protein-Serine-Threonine Kinases" 12 RBM19 30952614 EBioMedicine 2019 PMC6557749 10.1016/j.ebiom.2019.03.077 4 1 0 63 "*HIV-1|HIV Infections|Virus Latency|CD4-Positive T-Lymphocytes|Viral Load|CD8-Positive T-Lymphocytes|*Cells, B-1|T-Lymphocytes, Cytotoxic|Immunologic Memory|Dendritic Cells|Virus Replication|*HIV Seropositivity" 12 serpinb11 31609742 Clin Transl Gastroenterol 2019 PMC6884351 10.14309/ctg.0000000000000087 0 0 0 15 Adult|Humans|*Whole Exome Sequencing|*Pilot Projects|*Acute Liver Failure|Liver Transplantation 12 SLC43A3 30910793 Mol. Pharmacol. 2019 10.1124/mol.118.114389 0 4 0 81 "Humans|*Mercaptopurine|HEK293 Cells|*Biological Transport|Equilibrative Nucleoside Transporter 1|Purines|Hypoxanthine|SLC43A3 protein, human|Amino Acid Transport Systems" 12 TASP1 31350873 Mol Genet Genomic Med 2019 PMC6732342 10.1002/mgg3.818 1 0 0 65 "Humans|Female|Anterior segment mesenchymal dysgenesis|*Eye Abnormalities|*Craniofacial Abnormalities|*Mutation|Genetic Association Studies|Phenotype|Exome|Whole Exome Sequencing|Facies|*Anemia, Macrocytic|Transcription Factors" 12 TASP1 31209944 Hum. Mutat. 2019 10.1002/humu.23844 0 1 0 65 "Child|Male|Humans|*Methyltransferases, Histone|*Syndrome|KMT2A protein, human|*Myeloid-Lymphoid Leukemia Protein|*Histone-Lysine N-Methyltransferase|Kabuki syndrome|Abnormalities, Multiple|Phenotype|Facies|KMT2D protein, human|*DNA-Binding Proteins|*Homozygote|Microcephaly|Vestibular Diseases|Hematologic Diseases|*Neoplasm Proteins|Developmental Disabilities|Exons" 12 TMEM33 31048699 Nat Commun 2019 PMC6497644 10.1038/s41467-019-10045-y 0 1 0 152 "Mice|Animals|*Calcium|polycystic kidney disease 2 protein|Polycystins|Polycystic Kidney, Autosomal Dominant|Calcium Signaling|Endoplasmic Reticulum|Kidney|Zebrafish|Mutations|Kidney Tubules, Proximal|Homeostasis|Epithelial Cells" 12 TMEM33 30760708 Nat Commun 2019 PMC6374405 10.1038/s41467-019-08590-7 6 70 0 152 "Humans|Animals|Endothelial Cells|*Vascular Endothelial Growth Factor A|*Calcium Signaling|Neovascularization, Physiologic|Zebrafish|*Vascular Endothelial Growth Factors|Zebrafish Proteins|Vascular Endothelial Growth Factor Receptor-2|Membrane Proteins|Phosphorylation|Cell Movement|Cell Proliferation|Calcium-Binding Proteins|Filopodia|*Neovascularization, Pathologic|*Morphogenesis" 12 WDR13 31050064 Cell Biol. Int. 2019 10.1002/cbin.11160 1 6 0 110 "Cattle|Animals|Mice|*Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Phosphoinositide 3 Kinase|*Satellite Cells, Skeletal Muscle|*Cell Differentiation|*Signal Transduction|Muscle Development|Cell Proliferation|Cells, Cultured|Myotubes|RNA, Messenger|Phosphoinositide-3 Kinase Inhibitors|WDR13 protein, mouse|Nuclear Proteins" 12 xpo7 30921348 PLoS ONE 2019 PMC6438607 10.1371/journal.pone.0208659 0 2 0 135 "Humans|Mice|Animals|Cells, Erythroid|Erythropoiesis|Kruppel-Like Transcription Factors|Mice, Knockout|*Cell Nucleus|Gene Expression Regulation, Developmental|Cell Differentiation|Base Sequence|Sequencing, RNA|Haemolytic Anaemia|Promoter Regions, Genetic|Phenotype" 12 ZDHHC23 31213527 J. Biol. Chem. 2019 PMC6690687 10.1074/jbc.RA119.009065 1 0 0 21 Humans|Large-Conductance Calcium-Activated Potassium Channel beta Subunits|Large-Conductance Calcium-Activated Potassium Channel alpha Subunits|Membrane Potentials|Patch-Clamp Techniques|Potassium|HEK293 Cells 12 ZDHHC23 30658672 J. Exp. Clin. Cancer Res. 2019 PMC6339410 10.1186/s13046-019-1033-2 0 0 0 21 "*Glioma|Glioblastomas|Brain Neoplasms|Neoplastic Stem Cells|Cell Self Renewal|Gene Expression Regulation, Neoplastic|Polycomb Repressive Complex 1|Cell Line, Tumor|Cell Proliferation" 12 ZPBP 31807615 Arch Anim Breed 2019 PMC6852858 10.5194/aab-62-69-2019 0 0 0 18 "Pregnancy|Female|Swine|Animals|Litter Size|*DNA Methylation|Gene Frequency|Genotype|Sus scrofa|Polymorphism, Single Nucleotide|Parturition|Promoter Regions, Genetic" 12 ZPBP 31333723 Front Genet 2019 PMC6624472 10.3389/fgene.2019.00646 4 0 0 18 "Male|Cattle|Animals|*RNA, Long Noncoding|*mRNA|Sequencing, RNA|Gene Expression Profiling|Spermatogenesis" 12 ZPBP 31313401 Mol. Carcinog. 2019 PMC6721979 10.1002/mc.23084 0 6 0 18 "Mice|Animals|*Receptor, Cholecystokinin B|Pancreatic Carcinoma|*Pancreatic Cancer|Carcinoma, Pancreatic Ductal|*Pancreas|Carcinoma in Situ|Genes, ras|Mice, Transgenic|Signal Transduction|Cell Proliferation|Gene Expression Regulation, Neoplastic|Disease Progression|Cell Line, Tumor|YF 476|Phenylurea Compounds|Benzodiazepinones|*Chemoprevention" 12 ZPBP 31060552 Reprod. Biol. Endocrinol. 2019 PMC6503383 10.1186/s12958-019-0486-7 1 0 0 18 "Rats|Animals|Male|*Resveratrol|*Spermatogenesis|Testis|Spermatozoa|Follicle Stimulating Hormone|Luteinizing Hormone|Testosterone|Malondialdehyde|Reproduction|Superoxide Dismutase|Rats, Sprague-Dawley|Physical Conditioning, Animal" 12 ADGB 30043084 Trop Anim Health Prod 2018 10.1007/s11250-018-1670-z 0 0 0 6 12 ADGB 29489655 Medicine (Baltimore) 2018 PMC5851764 10.1097/MD.0000000000010043 2 0 0 6 12 AIFM3 30170380 Medicine (Baltimore) 2018 PMC6392549 10.1097/MD.0000000000011887 0 6 0 23 "Humans|*RNA, Long Noncoding|*Urinary Bladder Neoplasms|*Prognosis|miRNA|mRNA|Gene Ontology|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Kaplan-Meier Estimate|Genes, cdc|Genes, Homeobox|MIRN195 microRNA, human" 12 ANKRD30A 30079052 Front Neurol 2018 PMC6062961 10.3389/fneur.2018.00591 3 5 0 4 12 C15orf41 30108417 Bioinformation 2018 PMC6077826 10.6026/97320630014206 1 0 0 29 "Humans|Anemia, Dyserythropoietic, Congenital|Mutation|*Models, Structural|Protein Processing, Post-Translational|Protein Interaction Maps|Erythroblasts|Phosphorylation|Acetylation|Ubiquitination|Protein Isoforms|Open Reading Frame" 12 C15orf41 29901818 Eur. J. Haematol. 2018 10.1111/ejh.13112 3 0 0 29 "*Anemia, Dyserythropoietic, Congenital|Anemia, Hemolytic, Congenital|Erythroblasts|Mutation|Vesicular Transport Proteins|Nuclear Proteins|*Chromosome Structures|Bone Marrow|Genes, Regulator" 12 C15orf41 29846281 J. Pediatr. Hematol. Oncol. 2018 10.1097/MPH.0000000000001207 2 0 0 29 "Humans|Male|Adolescent|*Anemia, Dyserythropoietic, Congenital|*Anemia, Hemolytic, Congenital|*Sequencing, Next-Generation|Mutations|Genotype|Vesicular Transport Proteins|Nuclear Proteins|SEC23B protein, human" 12 C15orf41 29599085 Blood Cells Mol. Dis. 2018 PMC5947870 10.1016/j.bcmd.2018.03.002 1 1 0 29 "Pregnancy|Female|Humans|*Anemia, Dyserythropoietic, Congenital|Hydrops Fetalis|Nuclear Proteins|Glycoproteins|Mutation|*Transcription Factors|HAMP protein, human|Hepcidin|Iron Overload|*Labor Presentation|CDAN1 protein, human" 12 C6orf106 30311108 Mol. Cell. Biochem. 2018 10.1007/s11010-018-3455-0 2 3 0 80 "*Pancreatic Cancer|CCND1 protein, human|Cyclin D1|CDH1 protein, human|E Cadherin|CCNE1 protein, human|Cyclin E|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Oncogene Proteins|Cell Proliferation|Neoplasm Staging|Cell Movement|Signal Transduction|Cell Line, Tumor|Lymphatic Metastasis|Apoptosis|Antigens, CD" 12 C6orf106 29802199 J. Biol. Chem. 2018 PMC6036214 10.1074/jbc.RA117.001491 1 4 0 80 "Humans|*Chromosome 6|IRF3 protein, human|*Interferon Regulatory Factor 3|*Antiviral Agents|Respirovirus Infections|Sendai virus|Interferon-beta|Signal Transduction|Immunity, Innate|Interferon|RNA, Double-Stranded|CREBBP protein, human|CREB-Binding Protein|Poly I-C|Phosphorylation|HeLa Cells|C6orf106 protein, human" 12 C6orf106 29608557 PLoS Genet. 2018 PMC5897035 10.1371/journal.pgen.1007222 6 0 0 80 "Animals|Humans|*Body Mass Index|*Drosophila melanogaster|*Genome-Wide Association Study|*RNA Interference|SNPs|Obesity|Quantitative Trait Loci|Phenotype|Genetic Predisposition to Disease|Adipose Tissue|Adiposity|ARIH1 protein, human|Carrier Proteins|ZCCHC8 protein, human|Nuclear Proteins|VKORC1 protein, human|Vitamin K Epoxide Reductases" 12 calr3 29988065 Eur. J. Hum. Genet. 2018 PMC6189092 10.1038/s41431-018-0208-1 0 0 0 22 "Humans|*Cardiomyopathy|Heterozygote|High-Throughput Nucleotide Sequencing|Mutation, Missense|Sequence Analysis, DNA|Cardiomyopathy, Hypertrophic|Pedigree|Mutation|Cohort Studies" 12 calr3 29310583 BMC Genomics 2018 PMC5759888 10.1186/s12864-017-4427-6 1 14 0 22 Animals|Chick Embryo|Humans|*Proteomics|*Chickens|*Obesity|Gene Expression Profiling|Liver 12 FAM135B 30391288 Neurobiol. Dis. 2018 10.1016/j.nbd.2018.10.019 2 1 0 6 "Humans|*Bulbo-Spinal Atrophy, X-Linked|Neurodegenerative Diseases|*Motor Neurons|*Muscular Atrophy|AR protein, human|Androgen Receptor|*Phenotypes|Induced Pluripotent Stem Cells|Trinucleotide Repeat Expansion|*Neurons, Efferent|Neurite|Cell Differentiation|Cells, Cultured|polyglutamine|Peptides" 12 FAM135B 29927694 Epigenetics 2018 PMC6140809 10.1080/15592294.2018.1465790 5 1 0 6 "Humans|*Squamous Cell Carcinoma of Head and Neck|*DNA Methylation|*B-DNA|Prognosis|Head and Neck Neoplasms|Gene Expression Regulation, Neoplastic|Bioinformatics|Biomarkers, Tumor|Gene Expression Profiling|Receiver Operating Characteristic|Software" 12 FAM135B 29502064 Nan Fang Yi Ke Da Xue Xue Bao 2018 PMC6743880 1 0 0 6 "Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Lysine|Carcinoma, Squamous Cell|Lymphatic Metastasis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Neoplasm Staging|*Acetyltransferases" 12 FGD6 29888248 Int J Genomics 2018 PMC5985066 10.1155/2018/8231547 1 0 0 74 Humans|Child|*Whole Exome Sequencing|Autism Spectrum Disorder|Exome|Genetic Predisposition to Disease|Genetic Testing|High-Throughput Nucleotide Sequencing 12 hcg18 30426533 J. Cell. Biochem. 2018 10.1002/jcb.27954 2 1 0 0 "Humans|*RNA, Long Noncoding|*Urinary Bladder Neoplasms|*Bladder|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Prognosis|Cell Movement|Disease Progression|Biomarkers, Tumor|Apoptosis|Signal Transduction|Cell Line, Tumor|Carcinogenesis|NOTCH1 protein, human|Receptor, Notch1" 12 hcg18 30039593 Cell Prolif. 2018 PMC6528936 10.1111/cpr.12483 14 0 0 0 *Nucleus Pulposus|*Long Non-Coding RNA|*Intervertebral Disc Degeneration|Intervertebral Disc|MicroRNAs|Signal Transduction|Cell Proliferation|Apoptosis|Extracellular Matrix|Cell Differentiation 12 hcg18 30426533 J. Cell. Biochem. 2018 10.1002/jcb.27954 2 1 0 0 "Humans|*RNA, Long Noncoding|*Urinary Bladder Neoplasms|*Bladder|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Prognosis|Cell Movement|Disease Progression|Biomarkers, Tumor|Apoptosis|Signal Transduction|Cell Line, Tumor|Carcinogenesis|NOTCH1 protein, human|Receptor, Notch1" 12 hcg18 30039593 Cell Prolif. 2018 PMC6528936 10.1111/cpr.12483 14 0 0 0 *Nucleus Pulposus|*Long Non-Coding RNA|*Intervertebral Disc Degeneration|Intervertebral Disc|MicroRNAs|Signal Transduction|Cell Proliferation|Apoptosis|Extracellular Matrix|Cell Differentiation 12 IRF2BPL 30166628 Genet. Med. 2018 10.1038/s41436-018-0143-0 2 0 0 58 "Whole Exome Sequencing|Epilepsy|Exome|Seizures|Phenotype|Mutation|Carrier Proteins|Sequencing, Next-Generation" 12 IRF2BPL 30057031 Am. J. Hum. Genet. 2018 PMC6081494 10.1016/j.ajhg.2018.07.006 0 0 0 58 "Child|Humans|Animals|*Phenotypes|Hypotonia|Van der Woude syndrome|Abnormalities, Multiple|Heterozygote|Developmental Disabilities|Neurodevelopmental Disorders|Intellectual Disability|Seizures|Mutation|Alleles|Transcription Factors|Cerebellar Ataxia|Mutation, Missense|Drosophila melanogaster|Nervous System Malformations|Cleft Lip|Cleft Palate" 12 IRF2BPL 29374064 Cancer Res. 2018 10.1158/0008-5472.CAN-17-2403 0 12 0 58 "*Stomach Neoplasms|beta Catenin|Neoplasm Invasiveness|*Catenins|Wnt Signaling Pathway|Cell Proliferation|Cell Movement|Gene Expression Regulation, Neoplastic|DNA Methylation|Cell Line, Tumor|Promoter Regions, Genetic|Forkhead Transcription Factors|Apoptosis" 12 KDM4E 30377206 Cancer Epidemiol. Biomarkers Prev. 2018 PMC6363884 10.1158/1055-9965.EPI-17-0984 1 0 0 7 "United States|Kentucky|*Carcinoma, Non-Small-Cell Lung|*Squamous Cell Carcinoma|Lung Cancers|Adenocarcinoma|Mutation|Epithelial Cells|Appalachia|Cohort Studies" 12 KDM4E 30271150 Int J Nanomedicine 2018 PMC6154708 10.2147/IJN.S168928 2 29 0 7 "*Osteogenesis|*Mesenchymal Stem Cells|*Transcriptome|*Cell Differentiation|Stem Cell|MicroRNAs|RNA, Long Noncoding|Adipose Tissue|*Epigenesis, Genetic|RNA, Messenger|Epigenetic" 12 KDM4E 29927684 Epigenetics 2018 PMC6260135 10.1080/15592294.2018.1481703 0 3 0 7 "Mice|Animals|*Histone|*Osteogenesis|KDM1A protein, human|*Histone Demethylases|Jumonji Domain-Containing Histone Demethylases|*Cytokines|Methylation|Osteoclast|Cell Differentiation|Lysine|Macrophages|Epigenetic|Aggregatibacter actinomycetemcomitans|Lipopolysaccharides|Inflammation" 12 KDM4E 29685975 "Philos. Trans. R. Soc. Lond., B, Biol. Sci." 2018 PMC5915715 10.1098/rstb.2017.0071 2 13 0 7 Jumonji Domain-Containing Histone Demethylases|Lysine|Histones|Substrate Specificity|Protein Conformation|2-Oxoglutarate|Catalysis 12 KDM4E 29453221 Development 2018 10.1242/dev.158261 10 0 0 7 "Cattle|Animals|*Cellular Reprogramming|*Embryonic Development|Nuclear Transfer Techniques|Cloning, Organism|Embryo, Mammalian|Blastocyst|Histones|Histone Demethylases|Fertilization in Vitro|DNA Methylation|Protein Processing, Post-Translational|Epigenesis, Genetic|Lysine|*Epigenetic" 12 KIAA1324 30175151 Biomed Res Int 2018 PMC6106857 10.1155/2018/9416515 3 8 0 54 Humans|Female|*Computational Biology|*Adenoma|*Colorectal Cancer|*Adenocarcinoma|Cancer Screening|Prognosis|Carcinoma|*Uterine Cervical Neoplasms 12 KIAA1324 29967001 Cancer Epidemiol. Biomarkers Prev. 2018 PMC6719542 10.1158/1055-9965.EPI-17-0728 3 0 0 54 12 MS4A12 29764119 Cancer Res Treat 2018 PMC6333986 10.4143/crt.2018.157 0 0 0 16 "Humans|*Whole Exome Sequencing|Poland|*Incidence|*Melanoma|Exome|Mutations, Germline|Genetic Predisposition to Disease|Pedigree|Mutation" 12 NOMO1 29662609 Oncotarget 2018 PMC5882300 10.18632/oncotarget.24574 0 5 0 54 12 OTUD6B 30364145 Front Genet 2018 PMC6192414 10.3389/fgene.2018.00464 1 0 0 43 "Exome|Phenotype|Intellectual Disability|Pedigree|Mutation|Sequence Analysis, DNA" 12 PRAP1 30221683 Int. J. Mol. Med. 2018 PMC6202076 10.3892/ijmm.2018.3883 3 3 0 55 "*Synoviocytes|*Down-Regulation|*S Phase|*Aspirin|STAT3 protein, human|*STAT3 Transcription Factor|*Signal Transduction|*Apoptosis|*Fibroblast|*Rheumatoid Arthritis|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Proliferation|Synovial Membrane|Cell Cycle|NF-kappa B|Viability, Cell|CCND1 protein, human" 12 PRAP1 29922213 Front Neurol 2018 PMC5996890 10.3389/fneur.2018.00282 0 31 0 55 "Mice|Animals|*Oligodendrocyte Precursor Cells|*Remyelination|*Receptor, PAR-1|*Subarachnoid Hemorrhage|Oligodendroglia|Myelin Sheath|*Signal Transduction|White Matter|Stem Cells|Cell Differentiation|Disease Models, Animal|Cells, Cultured" 12 PRAP1 29886035 Gene 2018 10.1016/j.gene.2018.06.017 2 5 0 55 "Humans|*Cisplatin|*Endothelial Cells|Activating Transcription Factor 3|DNA Damage|Apoptosis|Cell Line, Tumor|ATF3 protein, human" 12 RASL11A 30224643 Nat. Genet. 2018 PMC6380472 10.1038/s41588-018-0211-z 8 5 0 8 "*Promoter Regions, Genetic|*Databases, Genetic|*Colorectal Cancer|*Mutations|Regulatory Sequences, Nucleic Acid|Computational Biology|Genomics|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms" 12 TASP1 30573454 Genes Dev. 2018 PMC6317322 10.1101/gad.319830.118 6 3 0 65 "Myeloid-Lymphoid Leukemia Protein|*Leukemia|Histone-Lysine N-Methyltransferase|*Proteolysis|Endopeptidases|Chromosomal Translocations|Cell Transformation, Neoplastic|Amino Acid Sequence" 12 TASP1 29633245 Clin. Genet. 2018 10.1111/cge.13258 1 0 0 65 "Infant|Child|Humans|Mice|Animals|Growth Deficiency and Mental Retardation with Facial Dysmorphism|*Microcephaly|Homozygote|Sequence Deletion|*Abnormalities, Multiple|Facies|Intellectual Disability|Developmental Disabilities|Phenotype|Myeloid-Lymphoid Leukemia Protein|Growth Disorders|Exons|Musculoskeletal Abnormalities|Contracture" 12 WDR13 30369599 Nutr Diabetes 2018 PMC6204428 10.1038/s41387-018-0065-6 0 0 0 110 "Mice|Animals|*Streptozocin|*Streptozotocin Diabetes|Insulin-Secreting Cells|Diabetes Mellitus, Type 1|Insulin|Blood Glucose|Cell Proliferation|Apoptosis|WDR13 protein, mouse|Nuclear Proteins" 12 WDR13 29743870 Front Mol Neurosci 2018 PMC5930177 10.3389/fnmol.2018.00133 0 3 0 110 "Male|Mice|Animals|Anxiety|Depression|Social Isolation|Stress, Psychological|Behavior, Animal|Hippocampus" 12 xpo7 29748336 J. Cell Biol. 2018 PMC6028547 10.1083/jcb.201712013 12 14 0 135 "*Active Transport, Cell Nucleus|exportin 1 protein|Exportins|*Receptors, Cytoplasmic and Nuclear|ran GTP-Binding Protein|Pores, Nuclear|Cell Nucleus|Cytoplasm|Protein Binding|Protein Conformation" 12 xpo7 29545601 Sci Rep 2018 PMC5854632 10.1038/s41598-018-22858-w 23 20 0 135 "Rats|Animals|Frontotemporal Dementia With Motor Neuron Disease|*Frontotemporal Dementia|*Amyotrophic Lateral Sclerosis|*Active Transport, Cell Nucleus|*Pick Disease of the Brain|*DNA-Binding Proteins|RNA Binding Protein|Neurons|exportin 1 protein|Exportins|Mutation|Cytoplasm" 12 ZPBP 30549223 Andrology 2018 10.1111/andr.12569 1 1 0 18 Horses|Male|Animals|*Zona Pellucida|*Serine Protease|*Spermatozoa Capacitation|Acrosome Reaction|Sperm-Ovum Interactions|Spermatozoa|Epididymis|Testis|*Serine Endopeptidases 12 ZPBP 29358633 Sci Rep 2018 PMC5778054 10.1038/s41598-018-19497-6 19 5 0 18 "Male|Mice|Animals|*Sperm|Oocytes|Phosphoinositide Phospholipase C|Sperm Injections, Intracytoplasmic|Fertilization|Fertilization in Vitro|Calcium Signaling" 12 ACTL7A 29058301 Pathol. Oncol. Res. 2017 10.1007/s12253-017-0313-4 7 0 0 4 "Humans|Male|*Carcinoma, Transitional Cell|*Urinary Bladder|*Testis|Urinary Bladder Neoplasms|MAGEA3 protein, human|Neoplasm Proteins|Antigens, Neoplasm|Biomarkers, Tumor|mRNA|ACTL7A protein, human|Actins|TSGA10 protein, human|Proteins|PIWIL2 protein, human|Argonaute Proteins" 12 AIFM3 28968550 Neoplasia 2017 PMC5633352 10.1016/j.neo.2017.06.007 7 21 0 23 "*MicroRNAs|*Organoids|*Extracellular Vesicle|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Cell Proliferation|mRNA|*Phenotype|Cell Line, Tumor|*Stomach|Co-culture" 12 AIFM3 28121514 N. Engl. J. Med. 2017 PMC5559731 10.1056/NEJMoa1609009 35 0 0 23 "*DiGeorge Syndrome|Shprintzen Golberg craniosynostosis|*Arachnodactyly|*Marfan Syndrome|*Craniosynostoses|*Kidney|Adaptor Proteins, Signal Transducing|Chromosome Deletion|Phenotype|Nuclear Proteins" 12 ALKBH7 29076432 Curr Stem Cell Res Ther 2017 10.2174/1574888X12666171027105532 1 1 0 15 "Animals|*Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Escherichia coli|*Epigenesis, Genetic|AlkB Enzymes|DNA Repair|Dioxygenases|Ketoglutaric Acids|Escherichia coli Proteins|*Oxidation-Reduction|DNA Methylation|DNA|RNA|Mixed Function Oxygenases|*Embryogenesis|AlkB protein, E coli" 12 ALKBH7 28893634 Mitochondrion 2017 10.1016/j.mito.2017.09.002 1 1 0 15 "Mice|Animals|*DNA, Mitochondrial|oxoguanine glycosylase 1, human|DNA Glycosylases|*DNA Repair|*Mitochondria|DNA Damage|Mice, Knockout|Oxidative Stress|Phenotype" 12 ALKBH7 28726787 Cell Death Dis 2017 PMC5550884 10.1038/cddis.2017.343 1 19 0 15 "Male|Female|Mice|Animals|*Alkylation|*Necrosis|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|AlkB Enzymes|DNA Repair|DNA Glycosylases|Cell Death|Apoptosis|DNA Damage|Antineoplastic Agents, Alkylating|Alkylating Agents" 12 ALKBH7 28231280 PLoS Comput. Biol. 2017 PMC5322872 10.1371/journal.pcbi.1005345 3 1 0 15 Humans|Male|*Prostate Cancer|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|African Americans|Genotype|Cancer Biomarkers|Case-Control Studies|Risk Factors|DNA Repair Enzymes 12 C15orf41 29049846 Pediatr Blood Cancer 2017 10.1002/pbc.26866 1 0 0 29 "Humans|Child|*Anemia, Dyserythropoietic, Congenital|*Interferon alpha-2|peginterferon alfa-2a|*Interferon-alpha|IFNA2 protein, human|Mutation|Erythropoiesis|Iron Overload|Nuclear Proteins|Polyethylene Glycols" 12 C15orf41 29031773 Gene 2017 10.1016/j.gene.2017.10.027 2 1 0 29 "Humans|Animals|*Anemia, Dyserythropoietic, Congenital|*Mutations|*Chinese|Genotype|*Genes, Regulator|Vesicular Transport Proteins|Nuclear Proteins|*Transcription Factors|Mutations, Missense|CDAN1 protein, human|Glycoproteins|SEC23B protein, human" 12 calr3 29238338 Front Microbiol 2017 PMC5712553 10.3389/fmicb.2017.02371 6 8 0 22 "*Calcimycin|Streptomyces|Gene Expression Regulation, Bacterial|Bacterial Proteins|Antibiotic" 12 calr3 28282460 PLoS ONE 2017 PMC5345761 10.1371/journal.pone.0173121 2 5 0 22 "*Immunogenic Cell Death|calreticulin, human|Calreticulin|Necrosis|quinone|*Benzoquinones|Apoptosis|Heat Shock Proteins|Cell Line, Tumor|Cell Death|R2016|*Quinones|Dendritic Cells|Downregulation|Up-Regulation|Melanoma|Carbazoles" 12 DNAH8 28985340 DNA Res. 2017 PMC5824824 10.1093/dnares/dsx037 3 1 0 24 "Cattle|Mice|Animals|Quantitative Trait Loci|Genome-Wide Association Study|*Genome Mapping|Breeding|*Genetics, Population|Polymorphism, Single Nucleotide|Fertility|Phenotype|Genomics" 12 FGD6 28855378 Mol. Biol. Cell 2017 PMC5662259 10.1091/mbc.E17-01-0059 7 33 0 74 "FLNA protein, human|*Filamins|*ADP-Ribosylation Factor|*Cell Migration|Actin|Actin Cytoskeleton" 12 FGD6 28494545 Zhonghua Gan Zang Bing Za Zhi 2017 10.3760/cma.j.issn.1007-3418.2017.04.007 0 0 0 74 12 HCG11 28677801 Int. J. Oncol. 2017 PMC5564403 10.3892/ijo.2017.4066 13 29 0 0 "Humans|*RNA, Long Noncoding|*Carcinoma, Hepatocellular|*Liver Neoplasms|*mRNA|*Insulin|*Phosphorylation|*Apoptosis|HepG2 Cell|*MAP Kinase Signaling System|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Signal Transduction|Cell Movement|Upregulation|CASP3 protein, human|Caspase 3|MicroRNAs|RNA Interference" 12 hcg18 29170907 J. Neurooncol. 2017 10.1007/s11060-017-2667-6 14 0 0 0 "Humans|*RNA, Long Noncoding|*Glioma|Prognosis|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate" 12 hcg18 29038477 Sci Rep 2017 PMC5643303 10.1038/s41598-017-13364-6 12 22 0 0 "Humans|Intervertebral disc disease|*Intervertebral Disc Degeneration|Tifab protein, human|*TNF Receptor-Associated Factor 6|Nucleus Pulposus|Downregulation|RNA, Long Noncoding|MicroRNAs|Up-Regulation|Apoptosis|Signal Transduction|Herniated Discs" 12 hcg18 29170907 J. Neurooncol. 2017 10.1007/s11060-017-2667-6 14 0 0 0 "Humans|*RNA, Long Noncoding|*Glioma|Prognosis|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate" 12 hcg18 29038477 Sci Rep 2017 PMC5643303 10.1038/s41598-017-13364-6 12 22 0 0 "Humans|Intervertebral disc disease|*Intervertebral Disc Degeneration|Tifab protein, human|*TNF Receptor-Associated Factor 6|Nucleus Pulposus|Downregulation|RNA, Long Noncoding|MicroRNAs|Up-Regulation|Apoptosis|Signal Transduction|Herniated Discs" 12 IRF2BPL 29017168 Cell. Physiol. Biochem. 2017 10.1159/000481872 6 2 0 58 "Animals|Rats|KISS1 protein, human|*Kisspeptins|Sexual Maturation|*Hypothalamus|Gonadotropin-Releasing Hormone|Transcription Factors|Securin|RNA, Messenger|Promoter Regions, Genetic|Rats, Sprague-Dawley|Kiss1 protein, rat" 12 KDM4E 28459457 Nat. Genet. 2017 PMC5703070 10.1038/ng.3844 96 14 0 7 "Mice|Humans|Animals|*Retroelements|Transcription Factor|Embryonic Development|Homeodomain Proteins|Mouse Embryonic Stem Cells|Genes, Homeobox|Gene Expression Regulation, Developmental|Chromatin|Zygote|POU5F1 protein, human|Octamer Transcription Factor-3|Myoblasts" 12 KDM4E 28364192 Cell. Mol. Life Sci. 2017 10.1007/s00018-017-2515-z 13 0 0 7 "*Methylation|*Arginine|Epigenesis, Genetic|Histones|*Protein Processing, Post-Translational|Protein Arginine Methyltransferase|Lysine|Histone Demethylases|Acetylation|TYRP1 protein, human|*Membrane Glycoproteins|Modifications, Histone|Demethylation" 12 KDM4E 28346812 SLAS Discov 2017 10.1177/2472555217699157 2 6 0 7 "Humans|Male|*Lysine|Jumonji Domain-Containing Histone Demethylases|*Prostate|*Prostate Cancer|pyrazolone|*Pyrazolones|benzimidazole|*Benzimidazoles|AR protein, human|Androgen Receptor|Histones|Enzyme Inhibitors|Crystallography, X-Ray|Cell Proliferation|KDM4A protein, human" 12 KDM4E 28051298 ACS Chem. Biol. 2017 PMC5404277 10.1021/acschembio.6b00958 15 10 0 7 *Histone|*Lysine|Jumonji Domain-Containing Histone Demethylases|Histone Lysine Demethylases|Substrate Specificity|2-Oxoglutarate|Post-Translational Modifications|Oxygenases|Oxygen 12 LRIT3 28334377 Invest. Ophthalmol. Vis. Sci. 2017 PMC5374884 10.1167/iovs.16-20745 5 1 0 31 "Mice|Animals|*Retinal Cone Photoreceptor Cells|Night blindness, congenital stationary|Night Blindness|Eye Diseases, Hereditary|Genetic Diseases, X-Linked|Retinal Bipolar Cells|Myopia|*Synaptic Transmission|Synapses|Retina|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|Dendrites|Disease Models, Animal|Calcium Channels, L-Type|Lrit3 protein, mouse|Membrane Proteins" 12 NOMO1 28963438 Clin. Sci. 2017 10.1042/CS20171231 2 1 0 54 "Humans|Mice|Animals|*Mesenchymal Stem Cells|Homeodomain Proteins|Tricho-dento-osseous syndrome|Hair Diseases|Craniofacial Abnormalities|Transcription Factors|Cell Differentiation|MicroRNAs|Mice, Transgenic|Phenotype|Dental Enamel Hypoplasia|Cell Proliferation|MIRN675 microRNA, human" 12 NOMO1 28416736 Oncotarget 2017 PMC5421859 10.18632/oncotarget.15478 3 1 0 54 Humans|Female|Homozygote|Sequence Deletion|Colorectal Cancer|Prognosis|Colonic Neoplasms|Colon 12 NOMO1 28339748 Neuro-oncology 2017 PMC5737684 10.1093/neuonc/now288 3 0 0 54 "Genome-Wide Association Study|*Glioma|*Genotype|Genetic Predisposition to Disease|Quantitative Trait Loci|Polymorphism, Single Nucleotide|Brain Neoplasms" 12 OTUD6B 29179949 J. Invest. Dermatol. 2017 10.1016/j.jid.2017.09.053 4 0 0 43 "Humans|*Long Non-Coding RNA|*Sclerosis|Upregulation|Gene Expression Regulation, Neoplastic|Sclerosis, Systemic|*Skin|Signal Transduction|Fibrosis|Cell Line, Tumor|Transcriptional Activation" 12 OTUD6B 28343629 Am. J. Hum. Genet. 2017 PMC5384096 10.1016/j.ajhg.2017.03.001 12 2 0 43 "Child|Humans|Mice|Animals|*Intellectual Disability|Leukocytes, Mononuclear|*Seizures|Microcephaly|Hypotonia|*Syndrome|Abnormalities, Multiple|Developmental Disabilities|Homozygote|Pedigree|Exome|Whole Exome Sequencing|Nervous System Malformations|Phenotype|Alleles|*Musculoskeletal Abnormalities|Mutation" 12 SERPINI2 29288362 J. Cancer Res. Clin. Oncol. 2017 10.1007/s00432-017-2558-4 4 0 0 24 "*Genes, Suppressor|*Pancreatic Cancer|*Downregulation|Gene Expression Regulation, Neoplastic|Genes, Tumor Suppressor|Oligonucleotide Array Sequence Analysis|DNA Methylation|Cell Line, Tumor|Gene Expression Profiling|RNA, Messenger" 12 SLC25A43 28781661 Oncol Lett 2017 PMC5530128 10.3892/ol.2017.6452 0 3 0 49 "Humans|*Basal Cell Carcinomas|*Skin|*Mitochondria|*Neoplasms, Basal Cell|Immunohistochemistry|Tumor Suppressor Proteins|Cell Proliferation|Gene Expression Regulation, Neoplastic|Epidermis|Epidermal Cells|Skin Neoplasms|SLC25A43 protein, human" 12 SLC25A43 28187360 Aquat. Toxicol. 2017 10.1016/j.aquatox.2017.02.004 4 0 0 49 "Animals|*Polychlorinated Biphenyls|*Transcriptome|Ecosystem|*Seals, Earless|Water Pollutants, Chemical|*Adipose Tissue|*Caniformia|Arctic Regions|Labrador|Canada" 12 SLC43A3 28768993 Biol. Pharm. Bull. 2017 10.1248/bpb.b17-00374 3 0 0 81 Animals|purine|Purines|*Biological Transport|Equilibrative Nucleoside Transporter 1|Nucleosides|pyrimidine|Pyrimidines|*Mammals|Membrane Transport Proteins 12 SNORD44 28781815 Mol Clin Oncol 2017 PMC5530321 10.3892/mco.2017.1319 0 0 0 0 "Humans|*Preliminary Data|MIRN372 microRNA, human|miRNA|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Upregulation|Real-Time Polymerase Chain Reaction|Downregulation" 12 SNORD44 28628844 Res. Vet. Sci. 2017 10.1016/j.rvsc.2017.06.001 3 0 0 0 "Pregnancy|Cattle|Female|Animals|*Buffaloes|*MicroRNAs|Sexual Maturation|Circulating MicroRNA|*Biomarkers|Pregnancy, Animal|Pregnancy Tests|Artificial Insemination|*Bison|Progesterone" 12 SNORD44 28530127 Hum. Gene Ther. 2017 10.1089/hum.2017.041 9 3 0 0 "Mice|Animals|*Adenovirus|Mice, Nude|Phosphatidylinositol 3-Kinases|*Colorectal Cancer|Oncolytic Viruses|Oncolytic Virotherapy|*Adenoviridae Infections|Genetic Vectors|RNA, Long Noncoding|Cell Proliferation|Transduction, Genetic|Apoptosis|Cell Line, Tumor|Genetic Therapy|Xenograft Model Antitumor Assays|Cell Cycle|MTOR protein, human|TOR Serine-Threonine Kinases" 12 SNORD44 28117343 Sci Rep 2017 PMC5259703 10.1038/srep41127 16 1 0 0 Humans|*miRNA|*Atrial Fibrillation|Gene Expression Profiling|Heart Atria|Reference Standards|Real-Time Polymerase Chain Reaction|Cardiac Surgical Procedures 12 SNORD44 28051134 Sci Rep 2017 PMC5209713 10.1038/srep39782 8 2 0 0 "Reproducibility of Results|MicroRNAs|Gene Expression Regulation, Neoplastic|*Tumor|Biomarkers, Tumor|Gene Expression Profiling|Small Nucleolar RNA|Quantitative Real Time PCR|Oncogenesis|Bioinformatic" 12 WDR13 28222755 BMC Cancer 2017 PMC5320654 10.1186/s12885-017-3118-7 0 27 0 110 "Humans|Mice|Animals|*WD Repeat|Azoxymethane|Dextran Sulfate|Colitis|Colonic Neoplasms|Colon|*Intestines|TYRP1 protein, human|*Membrane Glycoproteins|MicroRNAs|Gene Expression Regulation, Neoplastic|Inflammation|Disease Models, Animal|Signal Transduction|Transcription Factors|*Homeostasis|WDR13 protein, mouse|Nuclear Proteins" 12 ACTL7A 27692106 Injury 2016 10.1016/S0020-1383(16)30605-2 0 0 0 4 "Male|Humans|*Anterior Cruciate Ligament Injuries|*Anterior Cruciate Ligament|*Whole Exome Sequencing|*Siblings|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Exome|Genotype|Gene Frequency|Rupture|INDEL Mutation|Case-Control Studies|ACTL7A protein, human|Actins" 12 ACTL7A 26957350 Sci Rep 2016 PMC4783788 10.1038/srep22844 1 0 1 4 "Male|Humans|Female|Enzyme-Linked Immunosorbent Assay|Spermatozoa|Autoantibodies|Fertility|Female Infertility|ROC Curve|ACTL7A protein, human|Actins" 12 AIFM3 27473083 Tumour Biol. 2016 10.1007/s13277-016-5204-x 3 0 0 23 "Humans|*Apoptosis Inducing Factor|Proteomics|Chromatography, Liquid|Tandem Mass Spectrometry|*Cholangiocarcinoma|Bile Ducts, Intrahepatic|Bile Duct Neoplasms|Prognosis|*Mitochondrion|Biomarkers, Tumor|Cell Proliferation|Apoptosis|Tumor Cells, Cultured|Blotting, Western" 12 C6orf106 27121252 Int J Obes (Lond) 2016 10.1038/ijo.2016.72 7 0 0 80 "Middle Aged|Adult|Humans|*Body Mass Index|Cross-Sectional Studies|*Prospective Studies|*Ice Cover|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Triglycerides|Obesity|Alleles|Genotype|Life Style|Risk Factors|*Phenotype|Cardiovascular Diseases" 12 DNAH8 27363033 Oncotarget 2016 PMC5226506 10.18632/oncotarget.10284 4 22 1 24 "Humans|Male|*Prostate|*Receptors, Androgen|*Dyneins|Neoplasm Recurrence, Local|*Prostate Cancer|Androgens|*Signal Transduction|*Disease Progression|Prostatectomy|RNAi|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Cell Proliferation|*Neoplastic Processes|Cell Movement|Promoter Regions, Genetic" 12 DNAH8 26736064 Am. J. Respir. Crit. Care Med. 2016 PMC4910887 10.1164/rccm.201506-1223OC 22 0 0 24 "Genome-Wide Association Study|*Exome|*Chronic Obstructive Pulmonary Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Whole Exome Sequencing|Smoking|Case-Control Studies|*Genetic Testing" 12 FGD6 27089177 Nat. Genet. 2016 10.1038/ng.3546 14 0 0 74 "Humans|Animals|Mice|Wet Macular Degeneration|Choroidal Neovascularization|Asian|Gene Frequency|Polymorphism, Single Nucleotide|Alleles|Genotype|Polyps|*Mutation, Missense|Case-Control Studies|Cohort Studies|Odds Ratio" 12 FGD6 27005890 Hum. Reprod. 2016 10.1093/humrep/dew047 6 0 0 74 Humans|Female|*Endometriosis|*Endometrium|Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genotype 12 GAS2L1 28017616 Dev. Cell 2016 10.1016/j.devcel.2016.11.019 8 1 0 61 "Humans|*Centrioles|*Centrosome|CNTRL protein, human|*Cell Cycle Proteins|Microtubules|Spindle Apparatus|Interphase|Cytoskeletal Proteins|Actin|Chromosome Segregation|Microfilament Proteins|Binding Proteins|HeLa Cells|GAS2L1 protein, human" 12 GAS2L1 27638909 Nephrol. Dial. Transplant. 2016 10.1093/ndt/gfw313 1 1 0 61 "*Podocytes|advanced glycation end products-bovine serum albumin|*Glycation End Products, Advanced|Receptor for Advanced Glycation End Products|*Upregulation|Diabetic Nephropathies|Mesangial Cells|Bovine Serum Albumin|*Transcriptional Activation|Apoptosis|Signal Transduction|Diabetes Mellitus, Type 2|Cells, Cultured" 12 HCG11 27522256 Biomed. Pharmacother. 2016 10.1016/j.biopha.2016.08.013 21 0 0 0 "Humans|Male|*RNA, Long Noncoding|*Down-Regulation|*Prostate Cancer|Prognosis|Gleason Score|Gene Expression Regulation, Neoplastic|Kaplan-Meier Analysis|Disease Progression|Biomarkers, Tumor|Neoplasm Recurrence, Local|miRNAs|Cell Line, Tumor" 12 HCG11 26942882 Oncotarget 2016 PMC4991477 10.18632/oncotarget.7828 51 2 2 0 "Humans|*Long Non-Coding RNA|*Prognosis|Neoplasm Recurrence, Local|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Proliferation|Oncogenesis|Gene Expression Profiling|Cell Line, Tumor|Oncogenes|Kaplan-Meier Estimate|Upregulation" 12 KIAA1324 27716277 J Ovarian Res 2016 PMC5048446 10.1186/s13048-016-0272-5 2 2 1 54 "Humans|Female|*Ovarian Diseases|Anti-Mullerian Hormone|Infertility, Female|Ovarian Follicle|Ovary|Fertility" 12 KIAA1324 27230222 BMC Res Notes 2016 PMC4882813 10.1186/s13104-016-2086-3 0 1 1 54 "Humans|Female|*Endometrial Cancers|*Regulatory Region|Short Tandem Repeat|Polymorphism, Genetic|Genetic Predisposition to Disease|Alleles|Case-Control Studies|Risk|Estrogens|EIG121 protein, human|Membrane Proteins" 12 LRIT3 27428514 Ophthalmic Genet. 2016 10.1080/13816810.2016.1193876 0 0 0 31 "Humans|Night blindness, congenital stationary|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|*Mutation|Electroretinography|Pedigree|Phenotype|Genotype|Retinal Diseases|Retina|Visual Acuity|*Chinese|CABP4 protein, human|Calcium-Binding Proteins" 12 MS4A12 27881006 Neoplasma 2016 10.4149/neo_2017_108 1 0 0 16 "Humans|*Colon Cancer|*Cell Differentiation|Gene Expression Regulation, Neoplastic|CDH1 protein, human|E Cadherin|Colon|Up-Regulation|Prognosis|Down-Regulation|Cell Line, Tumor|Survival Analysis|Apoptosis|Membrane Proteins|Disease Progression|Antigens, CD" 12 MS4A12 27772553 Neurol. Neurochir. Pol. 2016 10.1016/j.pjnns.2016.06.008 1 0 0 16 "Humans|*Myalgia|Caveolin 3|*Mutation|*Caveolin 1|Homozygote|Muscle, Skeletal|Creatine Kinase|Missense Mutation|Phenotypes" 12 OTUD6B 27864334 Mol. Cancer Res. 2016 PMC5290186 10.1158/1541-7786.MCR-16-0281-T 9 20 0 43 "Humans|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|CCND1 protein, human|Cyclin D1|Signal Transduction|*Isoforms|Programmed Cell Death|Cell Proliferation|Cell Line, Tumor|Proto-Oncogene Proteins c-myc|Deubiquitinating Enzymes" 12 PRAP1 27153553 Oncotarget 2016 PMC5058763 10.18632/oncotarget.9146 4 1 1 55 "Humans|*Urinary Bladder Neoplasms|XRCC1 protein, human|X-ray Repair Cross Complementing Protein 1|X-ray repair cross complementing protein 3|DNA-Binding Proteins|Asian Continental Ancestry Group|XRCC2 protein, human|Genetic Predisposition to Disease|APEX1 protein, human|DNA-(Apurinic or Apyrimidinic Site) Lyase|Polymorphism, Single Nucleotide|Gene Frequency|DNA Repair|Genotype|Case-Control Studies|DNA Damage|China" 12 RBM19 27722056 Springerplus 2016 PMC5031565 10.1186/s40064-016-3275-1 1 0 1 63 "Humans|Poland|Holt-Oram syndrome|Upper Extremity Deformities, Congenital|Lower Extremity Deformities, Congenital|Ulnar-mammary syndrome|Abnormalities, Multiple|Heart Septal Defects, Atrial|Heart Defects, Congenital|T-Box Domain Proteins|Ulna|*Heart|Phenotype|Mutations|Breast Diseases" 12 RBM19 26931578 J. Leukoc. Biol. 2016 PMC4946617 10.1189/jlb.4VMR0915-395R 7 1 0 63 "Antigen Presentation|Dendritic Cells|Lymphocyte Activation|Immunity, Cellular|CD40 Ligand|T-Lymphocytes, Helper-Inducer|Antigen|Adaptive Immunity|Nanotubes" 12 RBM19 26883850 Genet. Sel. Evol. 2016 PMC4756527 10.1186/s12711-016-0190-4 23 0 1 63 "Female|Cattle|Animals|*Phenotypes|Chromosome Mapping|Quantitative Trait Loci|Genome-Wide Association Study|Genotype|Breeding|Lactation|Milk|Mammary Glands, Animal|Polymorphism, Single Nucleotide" 12 SERPINI2 27989643 Biochim Biophys Acta Proteins Proteom 2016 10.1016/j.bbapap.2016.10.013 1 3 0 24 "Mice|Animals|SERPINI2 protein, human|*Serpins|*Chymotrypsin|*Pancreatic Elastase|Escherichia coli|Serine Proteinase Inhibitors|*Neoplasm Proteins|Trypsin|Amino Acid Sequence|Binding Sites|Substrate Specificity|Sequence Homology, Amino Acid" 12 SLC25A43 26721434 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2015.12.088 2 6 0 49 "*Mitochondria|*Cell Division|Cell Proliferation|Tumor Suppressor Proteins|siRNA|Cell Cycle|Gene Silencing|Apoptosis|Cell Line, Tumor|Down-Regulation" 12 SLC43A3 27807008 J. Pharmacol. Exp. Ther. 2016 10.1124/jpet.116.236984 2 0 0 81 "Humans|Animals|Dogs|*Ganciclovir|*Thymidine Kinase|Genes, Transgenic, Suicide|Simplexvirus|*Antineoplastic Agents|Transfection|Antiviral Agents|Genetic Therapy|Genetic Vectors|Viability, Cell|Cell Line, Tumor|HeLa Cells|SLC43A3 protein, human|Amino Acid Transport Systems" 12 TASP1 27308523 Mol Cell Oncol 2016 PMC4905357 10.1080/23723556.2014.999513 2 9 0 65 TFIIA|*Endopeptidases|Amino Acid Sequence|Nuclear Proteins 12 TMEM33 27223089 Oncotarget 2016 PMC5129977 10.18632/oncotarget.9524 6 39 1 152 "Neoplasm Recurrence, Local|*Osteosarcoma|Bone Neoplasms|*Carcinogenesis|Apoptosis|Cell Proliferation|Neoplasm Invasiveness|Cell Cycle Arrest|Cell Line, Tumor|Cell Movement|Cell Cycle|RNA Interference|CASP3 protein, human|Caspase 3|RNA, Small Interfering|Caspase-7|RHOA protein, human|rhoA Protein" 12 WDR13 27625594 Front Mol Neurosci 2016 PMC5003927 10.3389/fnmol.2016.00073 2 4 1 110 "Male|Mice|Animals|*Spatial Memory|*Up-Regulation|*Anxiety|*Gene Deletion|Maze Learning|Cell Cycle Proteins|*Transcriptional Activation|Behavior, Animal|Nuclear Proteins|Hippocampus|Disease Models, Animal|Genes, jun|Phenotype|Neurons|WDR13 protein, mouse" 12 xpo7 27913688 Physiol. Genomics 2016 10.1152/physiolgenomics.00083.2016 1 0 0 135 "Animals|*Transcriptome|*Heart Ventricles|Running|Physical Conditioning, Animal|*Transcriptome Analysis|Muscle, Skeletal|RNA, Messenger|*Connective Tissue|Oxygen Consumption" 12 ZDHHC23 27536776 PLoS ONE 2016 PMC4990277 10.1371/journal.pone.0161539 4 2 1 21 "Humans|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Oncogene Proteins, Fusion|*Acute Disease|*Leukocyte Disorders|Blood Cell Count, White|BCAR3 protein, human|Adaptor Proteins, Signal Transducing" 12 AIFM3 26308446 PLoS ONE 2015 PMC4550359 10.1371/journal.pone.0136360 1 2 1 23 "Chlorocebus aethiops|Animals|Humans|*DNA, Complementary|*Myristic Acid|System, Cellfree|Amino Acid Sequence|Protein Biosynthesis|Transfections|Protein Processing, Post-Translational|Mitochondria|Membrane Proteins|COS Cells|*Biochemical Phenomena" 12 ANKRD30A 26301688 Nat. Med. 2015 PMC4863040 10.1038/nm.3933 52 0 5 4 12 ANKRD30A 26179511 Clin. Cancer Res. 2015 10.1158/1078-0432.CCR-14-2744 17 1 6 4 "Humans|Child|*Sarcoma, Ewing|*Neuroectodermal Tumors, Primitive, Peripheral|RNA-Binding Protein EWS|Proteins, Oncogene Chimeric|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|Cell Line, Tumor|Mutation|Mutation Rate|High-Throughput Nucleotide Sequencing" 12 ANKRD30A 25996380 Cancer Biol. Ther. 2015 PMC4622574 10.1080/15384047.2015.1040957 25 0 2 4 12 ANKRD30A 25884674 PLoS ONE 2015 PMC4401517 10.1371/journal.pone.0123624 1 3 0 4 "Animals|Humans|*Macaca mulatta|*Amino Acid Sequence|Simian Immunodeficiency Virus|Simian Acquired Immunodeficiency Syndrome|*Biological Evolution|Genes, cdc|PDCD5 protein, human|Neoplasm Proteins|Apoptosis Regulatory Proteins" 12 C6orf106 26683835 BMC Med. Genet. 2015 PMC4683724 10.1186/s12881-015-0259-x 10 1 1 80 "Humans|*Genetic Predisposition to Disease|Pakistan|*Obesity|Body Mass Index|*Physical Activity|*Smoking|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genome-Wide Association Study|European Continental Ancestry Group|Lifestyle|Alleles|*Tobacco Smoking|Genotype|Phenotype|Risk Factors" 12 C6orf106 25953261 Tumour Biol. 2015 10.1007/s13277-015-3500-5 5 3 0 80 "Humans|Carcinoma, Intraductal, Noninfiltrating|Carcinoma, Ductal, Breast|Lymphatic Metastasis|Triple-Negative Breast Cancer|Prognosis|Cell Proliferation|Neoplasm Invasiveness|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Neoplasm Staging|RNA, Messenger|Real-Time Polymerase Chain Reaction|*Disease Progression|Apoptosis|Tumor Cells, Cultured|C6orf106 protein, human" 12 C6orf106 25736925 Tumour Biol. 2015 10.1007/s13277-015-3274-9 4 9 0 80 "Humans|*Nonsmall Cell Lung Cancer|delta catenin|*Vimentin|Lung Cancer|*Catenins|CDH1 protein, human|*E Cadherin|*Upregulation|Lymphatic Metastasis|Antigens, CD|Neoplasm Invasiveness|Prognosis|*Downregulation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|*Transcriptional Activation|Cell Proliferation" 12 calr3 26252478 PLoS ONE 2015 PMC4529184 10.1371/journal.pone.0134967 1 1 1 22 "Humans|Male|*Testis|Antigens, Neoplasm|Lung Cancers|Neoplasm Proteins|Immunotherapy" 12 DNAH8 25917919 G3 (Bethesda) 2015 PMC4502369 10.1534/g3.115.018382 5 1 1 24 "Humans|Swine|Animals|Female|Male|Cattle|Sheep|*Whole Exome Sequencing|Sequence Analysis, RNA|Reproduction|High-Throughput Nucleotide Sequencing|Testis|Fertility|Gene Expression Profiling|Transcriptome|SNPs|Breeding|Phenotype|Finland|PIWIL2 protein, human|Argonaute Proteins" 12 FGD6 25629512 Nat Commun 2015 PMC4317498 10.1038/ncomms7063 50 4 5 74 "Humans|*Asian|*Age Related Macular Degeneration|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genetic Loci|Cholesterol Ester Transfer Proteins|European Continental Ancestry Group|Odds Ratio|Case-Control Studies|Risk Factors" 12 KDM4E 26555343 ACS Chem. Biol. 2015 10.1021/acschembio.5b00738 2 0 0 7 "Animals|*Lysine|Jumonji Domain-Containing Histone Demethylases|Histones|Demethylation|*Catalysis|Protein Conformation|Substrate Specificity|2-Oxoglutarate|Hydroxylation|Models, Molecular" 12 KIAA1324 26045166 Cancer Res. 2015 10.1158/0008-5472.CAN-14-3751 11 6 2 54 "Humans|*Stomach Neoplasms|*Stomach|molecular chaperone GRP78|Heat-Shock Proteins|*Molecular Chaperones|*Oncogene Proteins|Cell Line, Tumor|*Neoplastic Processes|Lymphatic Metastasis|Biomarkers, Tumor|Downregulation|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|DNA Methylation|*Disease Progression" 12 LRIT3 26427409 Adv. Exp. Med. Biol. 2015 PMC6716159 10.1007/978-3-319-17121-0_24 8 0 0 31 "Mice|Animals|Electroretinography|Retina|Retinal Disease|*Mutagenesis|Vision|Disease Models, Animal|Mutation|Lrit3 protein, mouse|Membrane Proteins" 12 LRIT3 26241901 Vis. Neurosci. 2015 PMC4648616 10.1017/S0952523815000012 5 0 0 31 "Humans|Mice|Animals|Night blindness, congenital stationary|*Alleles|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|Electroretinography|Retinal Bipolar Cells|Retina|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|Exons|Mutation|Pedigree|GRM6 protein, human|Receptors, Glutamate|Lrit3 protein, mouse|Membrane Proteins" 12 LRIT3 25997951 Eur. J. Neurosci. 2015 PMC4733627 10.1111/ejn.12959 16 4 1 31 "Humans|Mice|Animals|*Retinal Cone Photoreceptor Cells|Night blindness, congenital stationary|Night Blindness|Retinal Bipolar Cells|Eye Diseases, Hereditary|Genetic Diseases, X-Linked|Retina|metabotropic glutamate receptor 6|Receptors, Metabotropic Glutamate|Myopia|Dendrites|*Neurogenesis|Synapses|Signal Transduction|TRPM Cation Channels|Mutations|TRPM1 protein, human|Trpm1 protein, mouse" 12 LZIC 26316326 Hum. Mutat. 2015 PMC5054839 10.1002/humu.22899 6 0 1 155 "Humans|*5' Untranslated Regions|Leber Congenital Amaurosis|*DNA Mutational Analysis|Nicotinamide-Nucleotide Adenylyltransferase|Pedigree|*DNA Copy Number Variations|Mutation|Phenotype|Retinal Dystrophy|Heterozygote|Genetic Predisposition to Disease|*Eye Abnormalities|Blindness|NMNAT1 protein, human" 12 MS4A12 25929336 Oncotarget 2015 PMC4484419 10.18632/oncotarget.3198 6 3 0 16 "*Pseudomyxoma Peritonei|Peritoneal Neoplasms|Cytoreductive Surgery|Immunohistochemistry|*Gene Expression|Mucin-2|In Situ Hybridization|Biomarkers, Tumor|Appendix|*Cell Lines|Mutation|Oxaliplatin" 12 NOMO1 25576386 Exp. Cell Res. 2015 10.1016/j.yexcr.2014.12.016 0 4 0 54 "Humans|Mice|Animals|*Myocytes, Cardiac|*Differentiations, Cell|Transcription Factors|Homeodomain Proteins|Homeobox Protein Nkx-2.5|GATA4 Transcription Factor|T-Box Domain Proteins|Myocardium|Gene Expression Regulation, Developmental|SMAD2 protein, human|Smad2 Protein|RNA Interference|Cell Line|Signal Transduction" 12 RASL11A 26294325 Sci Rep 2015 PMC4543968 10.1038/srep13390 11 33 1 8 "*Metformin|*Aspirin|*Transcriptome|*Pancreatic Cancer|*Transcriptome Analysis|Downregulation|Gene Expression Regulation, Neoplastic|Up-Regulation|*Pancreas|Signal Transduction|Cell Line, Tumor|RNA, Messenger" 12 RBM19 26449790 J Crohns Colitis 2015 PMC6082592 10.1093/ecco-jcc/jjv178 4 0 0 63 "*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn Disease|*Intestines|Erythema Nodosum|*Eye|Odds Ratio|Arthritis|Logistic Models|Risk Factors" 12 RBM19 26423011 Lancet Respir Med 2015 PMC4593935 10.1016/S2213-2600(15)00283-0 126 1 13 63 "*Biological Specimen Banks|United Kingdom|*Chronic Obstructive Pulmonary Disease|*Smoking Behavior|Forced Expiratory Volume|Lung|*Study, Genetic Association|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype" 12 serpinb11 25875171 PLoS Genet. 2015 PMC4395385 10.1371/journal.pgen.1005122 2 3 0 15 "Horses|Animals|*Hoof and Claw|Genome-Wide Association Study|*Frameshift Mutation|*Phenotype|Alleles|Haplotype|Sequencing, Whole Genome|Case-Control Studies" 12 SLC43A3 26527604 Cancer Res. 2015 10.1158/0008-5472.CAN-15-0418 9 0 0 81 "Humans|*Hemangiosarcoma|Endothelial Cells|*Oncogene Fusion|Cell Proliferation|Oncogene Proteins, Fusion|Cell Line, Tumor|RNAi|Gene Expression|SLC43A3 protein, human|Amino Acid Transport Systems|NUP160-SLC43A3 fusion protein, human" 12 SLC43A3 26455426 Sci Rep 2015 PMC4796657 10.1038/srep15057 7 18 1 81 "Humans|Animals|HeLa Cells|purine|Purines|*Biological Transport|Nucleobase Transport Proteins|Hypoxanthine|*Mammals|Equilibrative Nucleoside Transporter 1|Nucleosides|Adenine|Guanine|Amino Acid Transporter|SLC43A3 protein, human" 12 SNORD44 26041889 Oncotarget 2015 PMC4627319 10.18632/oncotarget.4172 24 0 2 0 "Humans|Male|*RNA, Small Nucleolar|*Prostate Cancer|MicroRNAs|*Disease Progression|Gene Expression Regulation, Neoplastic|tRNA|Transcriptome|Cell Line, Tumor|*Cell Transformation, Neoplastic" 12 TASP1 26200114 PLoS ONE 2015 PMC4511561 10.1371/journal.pone.0133288 8 8 1 65 "Mice|Animals|*Transcriptome|Cardiomyocytes|Cell Cycle|Gene Expression Regulation|Networks, Gene|Cell Differentiation|Cell Division|Gene Ontology|Cell Proliferation|Organogenesis|Myocardial Infarction|Up-Regulation|Downregulation" 12 TASP1 25664857 J. Clin. Invest. 2015 PMC4362222 10.1172/JCI77075 5 2 0 65 "Mice|Animals|*Transcription Factor TFIIA|*Morphogenesis|Promoter Regions, Genetic|Cyclin-Dependent Kinase Inhibitor p16|Endopeptidases|Proteolysis|*Cyclin-Dependent Kinase Inhibitor Proteins|Craniofacial Abnormalities|Cell Proliferation" 12 TMEM33 26691022 PLoS ONE 2015 PMC4686535 10.1371/journal.pone.0145458 2 49 1 152 "Humans|*Class I Major Histocompatibility Molecules|*Cyclophilin C|Endoplasmic Reticulum-Associated Degradation|Chromatography, Liquid|Tandem Mass Spectrometry|Cytomegalovirus|Viral Envelope Proteins|Endoplasmic Reticulum|Viral Proteins|Membrane Proteins|Protein Binding|HLA-A2 Antigen|Cell Line|Hongkong|PDIA6 protein, human|Protein Disulfide-Isomerases" 12 TMEM33 26268696 Breast Cancer Res. Treat. 2015 PMC4559576 10.1007/s10549-015-3536-7 4 17 1 152 "*Unfolded Protein Response|*Endoplasmic Reticulum Stress|*Signal Transduction|X-Box Binding Protein 1|Endoribonucleases|*Membrane Proteins|eIF-2 Kinase|Activating Transcription Factor 6|Protein-Serine-Threonine Kinases|EIF-2|DNA-Binding Proteins|Activating Transcription Factor 4|Transcription Factor CHOP|Apoptosis|Transcription, Genetic|Cell Line, Tumor|Endoplasmic Reticulum" 12 TMEM33 25612671 Kobe J Med Sci 2015 9 2 0 152 *Binding Protein|Endoplasmic Reticulum|Nuclear Envelope|Membrane Proteins|Nogo Proteins|Biophysical Phenomena 12 WDR13 26306915 Sci Rep 2015 PMC4549788 10.1038/srep13371 4 8 2 110 "Mice|Female|Pregnancy|Animals|*Placenta|Placental Development|Trophoblast|Mice, Knockout|*Body Weight|Cell Lineage|Cell Differentiation|X-Linked Gene|WDR13 protein, mouse|Nuclear Proteins" 12 xpo7 25694352 J. Neurooncol. 2015 PMC4436689 10.1007/s11060-015-1741-1 4 12 1 135 "Oligodendrogliomas|*Mutations|Isocitrate Dehydrogenase|Brain Neoplasms|DNA Helicases|Repressor Proteins|DNA-Binding Proteins|Chromosome Deletion|Gene Expression Regulation, Neoplastic" 12 ZPBP 25634498 Chromosome Res. 2015 10.1007/s10577-014-9463-3 5 0 0 18 "Humans|Animals|*Camelids, New World|*Chromosome|*Cytogenetic|Karyotyping|Chromosome Mapping|Conserved Synteny|In Situ Hybridization, Fluorescence|Dromedary|Nucleolus Organizer Region|Genomics" 12 ACTL7A 24382234 Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2014 10.3881/j.issn.1000-503X.2013.06.002 0 1 0 4 Mice|Male|Animals|*Actins|*Testis|*Seminiferous Tubules|Sperm|Antibodies|*Active Immunization|Recombinant Proteins 12 ADGB 24966926 Int J Clin Exp Pathol 2014 PMC4069882 0 1 0 6 12 ALKBH7 25122757 J. Biol. Chem. 2014 PMC4183825 10.1074/jbc.M114.590505 8 2 1 15 "Humans|Mice|Animals|*Necrosis|*Proteins|*Apoptosis|DNA Damage|Alkylation|Crystallography, X-Ray|Oxidation-Reduction|RNA|Substrate Specificity|Dioxygenases|Mitochondria|Active Site|Membrane Potential, Mitochondrial|DNA|*Lipid Metabolism|AlkB Enzymes" 12 ANKRD30A 25134534 Nat Commun 2014 10.1038/ncomms5682 31 0 1 4 "Humans|Female|*Carcinoma, Ovarian Epithelial|*Genome-Wide Association Study|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|Genetic Susceptibility|Single Nucleotide Polymorphisms|*Asian Continental Ancestry Group|Genetic Loci|Genotype|Alleles|Case-Control Studies|Risk Factors|SURF6 protein, human|Nuclear Proteins" 12 ANKRD30A 24725956 Virology 2014 PMC4028154 10.1016/j.virol.2014.02.029 21 1 2 4 12 FAM135B 24670651 Nature 2014 10.1038/nature13176 293 0 39 6 "Humans|*Esophageal Squamous Cell Carcinoma|Comparative Genomic Hybridization|Esophageal Cancer|*Genomics|Carcinoma, Squamous Cell|Mutation|Exome|KMT2D protein, human|Neoplasm Proteins|DNA Copy Number Variations|Genetic Predisposition to Disease|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Esophagus|Sequence Analysis, DNA|Cell Cycle|Phenotypes|Genes, p16" 12 FGD6 24821726 J. Biol. Chem. 2014 PMC4140270 10.1074/jbc.M113.504894 15 1 2 74 "*Osteoclasts|*Guanine Nucleotide Exchange Factor|*Cell Polarity|RASGRF1 protein, human|*ras-GRF1|cdc42 GTP-Binding Protein|Cell Adhesion|Signal Transduction|rho GTP-Binding Proteins|Podosome|Actin|Cell Surface Extensions|Bone|*Endosomes" 12 GAS2L1 24706950 J. Cell. Sci. 2014 PMC4058111 10.1242/jcs.140558 21 11 3 61 "Chlorocebus aethiops|Animals|*Actins|*Binding Proteins|*Microtubules|Cytoskeletons, Actin|Microtubule-Associated Proteins|Microfilament Proteins|Protein Binding|Amino Acid Sequence|COS Cells" 12 KDM4E 25468267 Expert Opin Ther Pat 2014 10.1517/13543776.2014.991310 7 0 0 7 "*Histone|Histone Demethylases|Jumonji Domain-Containing Histone Demethylases|*Antineoplastic Agents|Enzyme Inhibitors|Cell Transformation, Neoplastic" 12 LRIT3 24715752 Mol. Vis. 2014 PMC3962728 5 2 0 31 "Humans|Night blindness, congenital stationary|*Pilot Projects|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|Electroretinography|Retina|Homozygote|Phenotype|*Asian Continental Ancestry Group|*Cohort Studies|Pedigree|Mutation|Visual Acuity|Amino Acid Sequence" 12 LRIT3 24598786 PLoS ONE 2014 PMC3943948 10.1371/journal.pone.0090342 24 4 3 31 "Humans|Mice|Animals|Night blindness, congenital stationary|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|Electroretinography|Retinal Bipolar Cells|Retina|Mutations|Knockout Mouse|Membrane Proteins|Phenotype|Disease Models, Animal|Lrit3 protein, mouse" 12 MS4A12 25423035 PLoS ONE 2014 PMC4244109 10.1371/journal.pone.0113071 14 1 3 16 "Humans|*Adenomatous Polyp|*Colonic Polyps|Colonic Neoplasms|*Carcinoma|MUC1 protein, human|Mucin-1|Immunohistochemistry|Biomarkers, Tumor|Gene Expression Profiling|In Situ Hybridization|Colon|*Rectal Neoplasms|Mucin|*Intestinal Polyposis|Cancer Screening|ACTG2 protein, human|Actins" 12 NOMO1 25520753 Mol Cytogenet 2014 PMC4269072 10.1186/s13039-014-0070-y 4 7 1 54 "*Chromatin|In Situ Hybridization, Fluorescence|*Metaphase|*Chromosomes|Interphase|DNA Probes" 12 NOMO1 25364968 J Craniofac Surg 2014 PMC4224967 10.1097/SCS.0000000000001076 3 0 0 54 "Humans|*Facial Asymmetry|Nodal Protein|Left-Right Determination Factors|Body Patterning|Homeodomain Proteins|Paired Box Transcription Factors|Gene Expression Regulation, Developmental|Nuclear Proteins|*Downregulation|Transforming Growth Factor beta|Signal Transduction" 12 OTUD6B 24886063 J Transl Med 2014 PMC4022541 10.1186/1479-5876-12-121 0 3 0 43 "Mice|Humans|Animals|*Autoantibodies|Early Detection of Cancer|Biomarkers, Tumor|Antigens, Neoplasm|Enzyme-Linked Immunosorbent Assay" 12 PRAP1 24374861 J. Pathol. 2014 10.1002/path.4319 1 3 0 55 "Humans|*Carcinoma, Hepatocellular|*M Phase Cell Cycle Checkpoints|*Liver Neoplasms|Cell Cycle Proteins|*Signal Transduction|Mad2 Proteins|Mitosis|Nuclear Proteins|Chromosomal Instability|Downregulation|Cell Line, Tumor|Protein Isoforms|Proline" 12 RASL11A 24614869 PLoS ONE 2014 PMC3948688 10.1371/journal.pone.0090804 10 4 0 8 "Male|Animals|Mice|*DNA Methylation|*X-Rays|*BALB C Mice|DNA (Cytosine-5-)-Methyltransferases|DNA (Cytosine-5-)-Methyltransferase 1|*Genome|Epigenesis, Genetic|Promoter Regions, Genetic|Downregulation|*Radiography|RNA, Messenger" 12 RASL11A 24589602 Nan Fang Yi Ke Da Xue Xue Bao 2014 1 0 0 8 "Mice|Animals|*CpG Islands|*X-Rays|DNA Methylation|Promoter Regions, Genetic|*Radiography" 12 RBM19 25548234 J. Immunol. 2014 PMC4297732 10.4049/jimmunol.1401832 17 15 1 63 "Humans|*CD40 Ligand|Interleukin-12|Lymphocyte Activation|Cytotoxicity, Immunologic|Dendritic Cells|CD8-Positive T-Lymphocytes|T-Lymphocytes, Cytotoxic|T-Lymphocytes, Helper-Inducer|Cell Differentiation|Cell Communication|Interferon-gamma|Immune Responses, Cellular|Cell Movement|Signal Transduction|*Nanotube" 12 serpinb11 25337548 J Cancer Prev 2014 PMC4189469 10.15430/jcp.2013.18.3.209 7 13 0 15 "Humans|Female|Animals|*Chicken|*Prognosis|Lactation|*Epithelial Ovarian Cancer|*Ovarian Cancer|Oviduct|Ovary|Poultry Diseases|squamous cell carcinoma-related antigen|Serpins|Antigens, Neoplasm|Gene Expression Regulation, Neoplastic|Up-Regulation|MicroRNAs|Estrogens|Ovum|SPP1 protein, human|Secreted Phosphoprotein 1" 12 serpinb11 25029526 PLoS ONE 2014 PMC4110113 10.1371/journal.pone.0102610 6 0 2 15 "Humans|Male|CTLA4 protein, human|*CTLA-4 Antigen|*Oral Cancer|Gene Expression Regulation, Neoplastic|ErbB Receptors|Neoplasm Proteins|Tumor Suppressor Protein p53|Signal Transduction|Cell Line, Tumor|India|TP53 protein, human|CTGF protein, human|SKIL protein, human|Proto-Oncogene Proteins|Intracellular Signaling Peptides and Proteins|CD70 protein, human|CD27 Ligand|EGFR protein, human" 12 serpinb11 24785531 J Immunoassay Immunochem 2014 10.1080/15321819.2014.917321 0 0 0 15 Male|Mice|Animals|*Spermatogenesis|Spermatocyte|Sperm|Testis|*Apoptosis|Spermatogonia|Meiosis 12 serpinb11 24781146 Cell Tissue Res. 2014 10.1007/s00441-014-1829-5 1 0 0 15 "Pregnancy|Female|Mice|Animals|*Implantation, Embryo|*Estrous Cycle|Pseudopregnancy|Uteri|Decidua|Progesterone|Oestradiol|Estrogens|mRNA|Proteins" 12 SNORD44 25203660 PLoS ONE 2014 PMC4159348 10.1371/journal.pone.0107519 7 9 0 0 "*RNA-Seq|*Cell Nucleolus|snoRNA|snoRNP|miRNAs|*Whole Exome Sequencing|Ribonuclease III|fibrillarin|Chromosomal Proteins, Non-Histone" 12 TASP1 25267403 Cell Res. 2014 PMC4220155 10.1038/cr.2014.129 10 26 1 65 "Humans|Female|Pregnancy|Mice|Animals|CCNE1 protein, human|*Cyclin E|*Cleavers|ERBB2 protein, human|*Receptor, ErbB-2|*Cell Transformation, Neoplastic|*Oncogene Proteins|Mice, Transgenic|Mammary Neoplasms, Experimental|Mammary Glands, Animal|Endopeptidases|*Oncogenes" 12 TMEM33 25413348 J. Cell. Sci. 2014 10.1242/jcs.158915 11 0 0 152 "*Nuclear Pore|*Nuclear Pore Complex Proteins|*Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Nuclear Import|Nuclear Envelope|*Yeast, Dried|beta Karyopherins|Nuclear Localization Signal|Karyopherins|Integral Membrane Protein|Nuclear Proteins|Amino Acid Sequence|Protein Structure, Secondary|Protein Binding|Lipids|Pom33 protein, S cerevisiae|Kap123 protein, S cerevisiae" 12 TMEM33 25103238 Mol. Biol. Cell 2014 PMC4230586 10.1091/mbc.E13-12-0729 7 6 0 152 "*Schizosaccharomyces|*Nuclear Envelope|*Mitosis|Bodies, Spindle Pole|Schizosaccharomyces pombe Proteins|Nuclear Pore Complex|Chromosome Segregation|Spindle Apparatus|Saccharomyces cerevisiae Proteins|Nuclear Division|Microtubule-Associated Proteins|Nuclear Proteins" 12 WDR13 25417213 Diabetologia 2014 10.1007/s00125-014-3438-y 6 0 2 110 "Mice|Animals|*Peroxisome Proliferator-Activated Receptors|Diabetes Mellitus, Type 2|leptin receptor, human|*Receptors, Leptin|Hyperinsulinism|Hyperglycemia|Insulin|*Phenotype|*Mice, Inbred Strains|Obesity|*Gene Deletion|Cell Proliferation|Signal Transduction|WDR13 protein, mouse|Nuclear Proteins" 12 xpo7 25092175 Blood 2014 PMC4168348 10.1182/blood-2013-11-537761 20 0 2 135 "Mice|Animals|*Histones|*Cytosol|Proteomics|Erythroblasts|*Cell Nucleus|Erythropoiesis|Chromatin|Cell Differentiation|Heterochromatin|Active Transport, Cell Nucleus|Nuclear Proteins|Cells, Cultured|Karyopherins" 12 xpo7 24625450 PLoS ONE 2014 PMC3953127 10.1371/journal.pone.0091000 16 6 3 135 "Humans|Female|*Carcinoma, Ovarian Epithelial|*Active Transport, Cell Nucleus|*Prognosis|*Cystadenocarcinoma, Serous|Spindle Apparatus|Mitosis|ran GTP-Binding Protein|Cell Cycle Proteins|Microtubule-Associated Proteins|Microtubules|Nuclear Proteins|Ovarian Neoplasms|Phosphoproteins|*Cell Nucleus Division|Cell Nucleus|Biomarkers|TPX2 protein, human|XPO7 protein, human" 12 ZDHHC23 24785229 Brain Inj 2014 10.3109/02699052.2014.888765 3 0 0 21 "Animals|Rats|*Dexmedetomidine|*Hippocampal Formation|*Signal Transduction|*Brain|Neuroprotective Agents|Rats, Sprague-Dawley|NOS1 protein, human|*Nitric Oxide Synthase Type I|Neurons|Apoptosis|Lipopolysaccharides|*Inhibition, Psychological" 12 ZDHHC23 24375959 Am. J. Med. Genet. A 2014 10.1002/ajmg.a.36346 2 0 0 21 "Male|Infant|Humans|Comparative Genomic Hybridization|*Abnormalities, Multiple|Chromosome Duplication|Chromosome Deletion|DiGeorge Syndrome|Facies|Intellectual Disability|*Musculoskeletal Abnormalities|In Situ Hybridization, Fluorescence|Genotype-Phenotype Correlations|*Chromosome Structures|Gene Dosage" 12 ACTL7A 23643272 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2013 0 1 0 4 "Humans|Male|Animals|Rabbits|*Actins|*Antibodies|*Sperm|Antibody Specificity|E coli|Gene Expression|Recombinant Fusion Proteins|Genetic Vectors|Cell Line|ACTL7A protein, human" 12 ADGB 23541529 Biochim. Biophys. Acta 2013 10.1016/j.bbapap.2013.03.021 27 0 2 6 "*Globins|*Archaea|Methylacidiphilum infernorum|Evolution, Molecular|Genome|Phylogeny|Myoglobin|Sequence Alignment|Bioinformatics|Bacteria" 12 ADGB 23360762 Biochim. Biophys. Acta 2013 10.1016/j.bbapap.2013.01.019 11 0 1 6 "Animals|Phylogeny|*Fossils|*Vertebrate|Evolution, Molecular|Gene Cluster|Genome|Gene Duplication|*Fishes|Myoglobin|Hemoglobins|Cytoglobin|Amino Acid Sequence|Neuroglobin" 12 ALKBH7 23666923 Genes Dev. 2013 PMC3672644 10.1101/gad.215533.113 23 3 2 15 "Animals|Humans|*Necrosis|*Apoptosis|Poly ADP Ribose Polymerase|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|*Alkylation|Cell Death|Mitochondria|Alkylating Agents|NAD|DNA Damage|Adenosine Triphosphate|DNA|Bioenergetics" 12 ALKBH7 23572141 J Mol Cell Biol 2013 10.1093/jmcb/mjt012 13 1 1 15 "Mice|Animals|*Obesity|Body Weight|Body Fat|Protein, Mitochondrial|Lipid Metabolism|Mitochondria|Oxidation-Reduction|Alkbh1 protein, mouse|AlkB Homolog 1, Histone H2a Dioxygenase" 12 C15orf41 23716552 Haematologica 2013 PMC3762094 10.3324/haematol.2013.089490 19 0 0 29 "Humans|*Anemia, Dyserythropoietic, Congenital|*Homozygote|*Mutations|Nuclear Proteins|Pedigree|*Endonucleases|Glycoproteins|Asian Continental Ancestry Group|Vesicular Transport Proteins|Erythropoiesis|Pakistan" 12 C6orf106 23354108 Spine 2013 10.1097/BRS.0b013e318287fcfd 8 1 1 80 "Humans|Adolescent|*Scoliosis|Sexual Maturation|*Genotype|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Genetic Association Studies|*Kyphosis|Asian Continental Ancestry Group|Case-Control Studies" 12 DNAH8 24307375 Hum. Mutat. 2013 PMC4285299 10.1002/humu.22490 14 0 6 24 "Humans|*Genetic Testing|Axonemal Dyneins|Kartagener Syndrome|Sequencing, Next-Generation|Exome|Sequence Analysis, DNA|Mutation|Genotypes|Cohort Studies" 12 FAM135B 24204716 PLoS ONE 2013 PMC3811986 10.1371/journal.pone.0076978 21 0 1 6 "Humans|Child|*Autistic Disorder|Case-Control Studies|Genetic Predisposition to Disease|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genotype|CNTNAP2 protein, human|Nerve Tissue Proteins|Phenotype|Membrane Proteins|*Survey|NLGN4X protein, human|Cell Adhesion Molecules, Neuronal" 12 FGD6 23792445 Oncogene 2013 10.1038/onc.2013.219 18 0 3 74 "Humans|Animals|Mice|*Annexin A2|EGFR protein, human|*Epidermal Growth Factor Receptor|*Signal Transduction|*Genes, erbB-1|*Cell Migration|Phosphorylation|Epidermal Growth Factor|Endocytosis|*Protein Transport|*Annexins|Cell Line, Tumor|Lung Neoplasms|RNA, Small Interfering|Triple-Negative Breast Cancer|Actin Depolymerizing Factors|HAX1 protein, human|Adaptor Proteins, Signal Transducing" 12 LZIC 23653380 Tumour Biol. 2013 10.1007/s13277-013-0825-9 7 4 0 155 "Humans|*Gallbladder Neoplasms|Vascular Endothelial Growth Factor A|*Cell Migration|*Pancreas|Pancreatic Cancer|Neoplasm Invasiveness|RNA, Small Interfering|Lymphatic Metastasis|Prognosis|Cell Proliferation|SCAMP1 protein, Sus scrofa|*Vesicular Transport Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|Downregulation" 12 RBM19 23913962 J. Immunol. 2013 PMC3786204 10.4049/jimmunol.1300373 23 5 3 63 "*HIV-1|HIV Infections|T-Lymphocytes, Cytotoxic|Epitopes, T-Lymphocyte|HLA-A2 Antigen|Dendritic Cells|*HIV Seropositivity|Cross Reactions" 12 SERPINI2 24134470 Anim. Genet. 2013 10.1111/age.12092 8 0 2 24 Animals|Cattle|Animal Feed|Eating|Phenotype|Breeding|Body Composition|Meat|Weight Gain|Genotype|Energy Metabolism|Adipose Tissue|Australia 12 SERPINI2 23793063 J Perinat Med 2013 PMC4164302 10.1515/jpm-2013-0082 15 5 0 24 "Pregnancy|Humans|Female|*Pre-Eclampsia|Oligonucleotide Array Sequence Analysis|Placenta|*Phenotype|Gene Expression Profiling|*Databases, Genetic|Case-Control Studies" 12 SLC25A43 23783460 Hum. Genet. 2013 10.1007/s00439-013-1322-3 5 0 0 49 "Humans|Male|*Intellectual Disability|Chromosomes, Human, X|*Syndromes|X Chromosome Inactivation|Comparative Genomic Hybridization|Pedigree|Mutations|*Chromosome Structures|*Mitochondria|Ubiquitin-Conjugating Enzymes|SLC25A43 protein, human|Tumor Suppressor Proteins" 12 SLC25A43 23354756 Oncol. Rep. 2013 PMC3621655 10.3892/or.2013.2247 2 8 0 49 "Humans|*Protein, Mitochondrial|Trastuzumab|Receptor, ErbB-2|*Cell Cycle Arrest|Paclitaxel|*Mitochondria|Antibodies, Monoclonal, Humanized|Antineoplastic Combined Chemotherapy Protocols|Epirubicin|Antineoplastic Agents|Cell Proliferation|Cell Line|SLC25A43 protein, human|Tumor Suppressor Proteins" 12 TMEM33 23848512 BMC Evol. Biol. 2013 PMC3727976 10.1186/1471-2148-13-150 20 0 6 152 "Humans|*Asian|Haplotypes|Gene Frequency|Selection, Genetic|Genetics, Population|European Continental Ancestry Group|Skin Pigmentation|African Continental Ancestry Group|Genetic Variation|Genotype|Polymorphism, Single Nucleotide|Linkage Disequilibrium|Evolution, Molecular|*Pigmentation Disorders|East Asia" 12 xpo7 23906023 Traffic 2013 10.1111/tra.12097 25 3 3 135 "Humans|KPNB1 protein, human|*beta Karyopherins|*Cell Nucleus|Nuclear Localization Signal|Nuclear Import|alpha Karyopherins|Importin|Cytoplasm|Protein Transport|Protein Binding|HeLa Cells|*Translocation, Genetic|IPO8 protein, human|XPO7 protein, human|ran GTP-Binding Protein" 12 xpo7 23523963 Mutat. 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Steril. 2012 10.1016/j.fertnstert.2012.11.005 2 0 1 4 Male|Animals|Mice|Sperm Capacitation|*Spermatozoa|Cyclic AMP-Dependent Protein Kinases|Cyclic AMP|Phosphorylation|Isoquinolines|Signal Transduction|Sulfonamides|Protein Kinase Inhibitors|Tyrosine 12 ACTL7A 22386842 Fertil. Steril. 2012 10.1016/j.fertnstert.2012.02.023 4 0 1 4 Male|*Infertility|Spermatozoon|Antibodies|Fertility|Antibody Specificity 12 AIFM3 22387901 Exp. Cell Res. 2012 10.1016/j.yexcr.2012.02.010 52 2 2 23 "Humans|*Carcinoma, Hepatocellular|*Down-Regulation|*Liver Neoplasms|*Apoptosis|*Radiosensitivity|MIRN210 microRNA, human|RNA, Micro|*Hypoxia|siRNA|Cell Proliferation|Cell Line, Tumor|Viability, Cell|Cell Hypoxia|Xenograft Model Antitumor Assays" 12 ALKBH7 23145062 PLoS ONE 2012 PMC3493508 10.1371/journal.pone.0049045 8 17 0 15 "Humans|Escherichia coli|AlkB Homolog 4, Lysine Demethylase|Dioxygenases|AlkB Homologs|2-Oxoglutarate|Chromatin|Gene Expression|RNA|Cell Nucleus|ALKBH3 protein, human|AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO" 12 calr3 22621904 Mol. Biol. Cell 2012 PMC3395656 10.1091/mbc.E11-12-1025 15 2 1 22 "Male|Female|Humans|Mice|Animals|Proteomics|*Spermatozoa|Zona Pellucida|Sperm-Ovum Interactions|Sperm Motility|Infertility, Male|Testis|Oviducts|Fertilization|ADAM Proteins|Fertility|Mice, Knockout|Membrane Glycoproteins|Fertilization in Vitro|Calcium-Binding Proteins|PDILT protein, human|Protein Disulfide-Isomerases|Adam3 protein, mouse" 12 calr3 22515980 Curr. Mol. Med. 2012 PMC3940075 10.2174/156652412800620020 17 14 0 22 "Humans|*Myofibrils|*Calcium|*Cardiomyopathy, Hypertrophic|*Actin Cytoskeleton|*Heart|*Mutations|Sarcomeres|phospholamban|Calcium-Binding Proteins|Ryanodine Receptor 2|junctophilin|Membrane Proteins" 12 calr3 22357757 Proc. Natl. Acad. Sci. U.S.A. 2012 PMC3309714 10.1073/pnas.1117963109 43 1 6 22 "Male|Female|Humans|Mice|Animals|*Protein Disulfide-Isomerases|TYRP1 protein, human|*Membrane Glycoproteins|Zona Pellucida|Spermatozoa|Sperm-Ovum Interactions|Testis|Sperm Motility|*Oxidoreductases|Infertility, Male|Fertilization|ADAM Proteins|Molecular Chaperones|Oviduct|Fallopian Tubes|ADAM 3|*Retinoids|Endoplasmic Reticulum" 12 FAM135B 22976950 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2012 10.1002/ajmg.b.32097 5 0 0 6 Female|Humans|Swine|Animals|*Haplotypes|*Infanticide|*Psychotic Disorders|Linkage Disequilibrium|Bipolar Disorder|*Puerperal Disorders|SNPs|Genetic Predisposition to Disease|Chromosome Mapping 12 KDM4E 23092293 Biochem. J. 2012 PMC4673901 10.1042/BJ20121155 24 6 4 7 "Humans|*Histone|*Ketoglutaric Acids|*Oxygen|Kinetics|Epigenesis, Genetic|Jumonji Domain-Containing Histone Demethylases|Histone Demethylases|Methylation|Demethylation|Lysine|Amino Acid Sequence" 12 LRIT3 23246293 Am. J. Hum. Genet. 2012 PMC3542465 10.1016/j.ajhg.2012.10.023 50 0 3 31 "Humans|Night blindness, congenital stationary|*Whole Exome Sequencing|*Night Blindness|*Eye Diseases, Hereditary|*Genetic Diseases, X-Linked|*Myopia|*Mutations|Electroretinography|Homozygote|Pedigree|Retina|Visual Acuity|Genotype|Retinal Cone Photoreceptor Cells|Heterogeneities, Genetic|Amino Acid Sequence" 12 LRIT3 22673519 FEBS Lett. 2012 PMC3372856 10.1016/j.febslet.2012.04.010 8 23 0 31 "*Leucine|Phosphatidylinositol 3-Kinases|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|Signal Transduction|*Immunoglobulin|Phosphorylation|Amino Acid Sequence|FLRT3 protein, human|Membrane Proteins|Mitogen-Activated Protein Kinases|*Protein Domains|Cloning, Molecular" 12 NOMO1 22832245 RNA Biol 2012 10.4161/rna.20807 49 2 6 54 "Humans|Female|Pregnancy|*Trophoblasts|Cell Line, Tumor|*Placenta|*Cell Proliferation|Pre-Eclampsia|*Genes, Tumor Suppressor|MicroRNAs|3' UTR|Downregulation|Cell Movement|SMAD2 protein, human|Smad2 Protein|Signal Transduction|DNA Methylation|Transforming Growth Factor beta|MIRN675 microRNA, human" 12 PRAP1 23235459 Cell Death Dis 2012 PMC3542616 10.1038/cddis.2012.180 12 48 0 55 "Humans|*Cell Survival|*Tumor Suppressor Protein p53|*DNA Damage|DNA Repair|Cell Cycle Arrest|Apoptosis|Cell Cycle|Signal Transduction|HCT116 Cells|Cell Line, Tumor|Upregulation" 12 RBM19 22984444 PLoS ONE 2012 PMC3440411 10.1371/journal.pone.0043786 3 3 0 63 "Animals|Phylogeny|Pre-rRNA|Saccharomyces cerevisiae Proteins|Base Sequence|Amino Acid Sequence|RNA-Binding Proteins|Saccharomyces cerevisiae|Protein Structure, Tertiary|Nucleic Acid Conformation|RNA-Binding Domains|Small Nucleolar RNA|Binding Sites|Conserved Sequence|Phosphoproteins|Mental Retardation, Autosomal Dominant 1|*Intellectual Disability" 12 serpinb11 22393410 PLoS ONE 2012 PMC3290568 10.1371/journal.pone.0032518 8 0 0 15 "Humans|Animals|*Gain of Function Mutation|Phylogeny|Selection, Genetic|Evolution, Molecular|Gene Cluster|Hominidae|*Host-Pathogen Interactions|Serpins|Pseudogene|Serine Protease Inhibitors" 12 serpinb11 22289513 Exp. Biol. Med. (Maywood) 2012 10.1258/ebm.2011.011250 11 0 0 15 "Animals|Female|Humans|*Chickens|*Carcinoma, Endometrioid|Ovarian Cancer|Apoptosis|Cell Line, Tumor|*Epithelial Ovarian Cancer|Oviducts|Ovary|mRNA|3' UTR|miRNA|SERPIN-B5|Serpins|Estrogens|Diethylstilbestrol|Gene Expression Regulation, Neoplastic|*Biomarkers" 12 SLC25A43 22887648 Am. J. Med. Genet. A 2012 10.1002/ajmg.a.35465 3 0 1 49 "Humans|Male|Holoprosencephaly, Ectrodactyly, and Bilateral Cleft Lip-Palate|*Cleft Lip|*Cleft Palate|*Holoprosencephaly|Ectrodactyly|Comparative Genomic Hybridization|*Hand Deformities, Congenital|*Intellectual Disability|*Limb Deformities, Congenital|*Fingers|*Syndrome|Receptor, Fibroblast Growth Factor, Type 1|SLC25A43 protein, human|Tumor Suppressor Proteins" 12 SLC25A43 22883974 BMC Cancer 2012 PMC3462703 10.1186/1471-2407-12-350 7 1 0 49 "Humans|Female|ERBB2 protein, human|Receptor, ErbB-2|*Cell Proliferation|Loss of Heterozygosity|Tumor Suppressor Proteins|Gene Expression Regulation, Neoplastic|*Mitochondrial Membrane Transport Proteins|In Situ Hybridization, Fluorescence|*Breast Cancer|SLC25A43 protein, human" 12 SLC25A43 22430806 Epigenetics 2012 10.4161/epi.7.3.19064 6 1 0 49 "Humans|*DNA Methylation|*B-DNA|ERBB2 protein, human|Receptor, ErbB-2|CpG Island|Gene Expression Regulation, Neoplastic|Loss of Heterozygosity|Gene Silencing|Azacitidine|Promoter Regions, Genetic|Decitabine|Epigenesis, Genetic|SLC25A43 protein, human|Tumor Suppressor Proteins" 12 SLC43A3 23268354 Mol. Aspects Med. 2012 10.1016/j.mam.2012.12.006 24 0 5 81 "Mice|Animals|*Amino Acid Transport System L|Amino Acid Transport Systems, Basic|TOR Serine-Threonine Kinases|Signal Transduction|Leucine|Mechanistic Target of Rapamycin Complex 1|Up-Regulation|Amino Acids|Amino Acids, Branched-Chain|Plasma Membrane|Zebrafish|Starvation" 12 SLC43A3 22848350 PLoS ONE 2012 PMC3405097 10.1371/journal.pone.0039103 18 0 6 81 "Humans|United States|Iodine-131|*Iodine Radioisotopes|*Chernobyl Nuclear Accident|*Thyroid Cancers|Cancers, Papillary Thyroid|Thyroid Gland|Carcinoma, Papillary|Neoplasms, Radiation-Induced|*Gene Expression|Cohort Studies|Mta1 protein, human|Histone Deacetylases|Repressor Proteins|LMO3 protein, human|Adaptor Proteins, Signal Transducing|LIM Domain Proteins|SLC43A3 protein, human|Amino Acid Transport Systems" 12 SNORD44 22788411 Int. J. Urol. 2012 10.1111/j.1442-2042.2012.03082.x 31 0 5 0 "Humans|Male|*Carcinoma, Renal Cell|*miRNA|*Urinary Bladder Neoplasms|*Prostate|Kidney Neoplasms|*Prostate Cancer|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Real-Time Polymerase Chain Reaction|*Rare Diseases" 12 WDR13 22715406 PLoS ONE 2012 PMC3371019 10.1371/journal.pone.0038685 5 4 2 110 "Humans|Mice|Animals|*Insulin-Secreting Cells|*Hyperinsulinism|*Obesity|*Cell Proliferation|Pancreatic Islet|Insulin|Strain, Mutant Mouse|Upregulation|WDR13 protein, mouse|Nuclear Proteins" 12 ZDHHC23 22399288 J. Biol. Chem. 2012 PMC3340283 10.1074/jbc.M111.335547 44 15 3 21 Humans|Animals|Large-Conductance Calcium-Activated Potassium Channels|Palmitoylation|*Acyltransferases|Thiolester Hydrolases|Cell Membrane|Palmitic Acid|Substrate Specificity|HEK293 Cells|Ion Channel|Cytosol 12 ACTL7A 21263130 J. Natl. Cancer Inst. 2011 10.1093/jnci/djq563 0 0 6 4 "Humans|*Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Chromosome Mapping|Case-Control Studies|European Continental Ancestry Group|Genotype|Odds Ratio|Risk Factors" 12 ADGB 22115833 Mol. Biol. Evol. 2011 PMC3350324 10.1093/molbev/msr246 32 0 6 6 "Animals|Mice|Male|*Testis|Evolution, Molecular|Phylogeny|Vertebrates|*Mammals|Genomes|Myoglobin|Amino Acid Sequence|Sequence Homology, Amino Acid|Hemoglobin|Protein Binding" 12 ADGB 21465106 Trop Anim Health Prod 2011 10.1007/s11250-011-9816-2 0 0 0 6 "Sheep|Animals|Horses|Iran|Sheep, Domestic|Breeding|Weaning|Weight Gain|Body Weight|Phenotype|*Genetic Testing|Birth Weight|Linear Models" 12 AIFM3 21841015 Am. J. Physiol. Heart Circ. Physiol. 2011 PMC3197368 10.1152/ajpheart.01080.2010 68 7 4 23 "Mice|Animals|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Myocytes, Cardiac|*Tumor Suppressor Protein p53|*Upregulation|*Hypoxia|Signal Transduction|MicroRNAs|Cell Hypoxia|Viability, Cell|Apoptosis|*Transcriptional Activation|Reactive Oxygen Species|Downregulation|MIRN210 microRNA, mouse" 12 C6orf106 22035010 Anim. Genet. 2011 10.1111/j.1365-2052.2011.02195.x 6 0 0 80 "Swine|Male|Animals|*Quantitative Trait Locus|*Testis|androst-16-en-3-one|*Androstenes|*Liver|Gene Expression Profiling|Haplotype|Polymorphism, Single Nucleotide|Adipose Tissue" 12 calr3 21700002 Eur J Med Genet 2011 10.1016/j.ejmg.2011.05.004 3 2 0 22 "Humans|Female|Child, Preschool|DNA Copy Number Variations|Split hand foot deformity|*Limb Deformities, Congenital|*Chromosome 11|Phenotype|Comparative Genomic Hybridization|Genotype-Phenotype Correlation|Chromosome Deletion|*Syndrome|*Chromosome Structures|*Rare Diseases" 12 FAM135B 21281516 BMC Res Notes 2011 PMC3041678 10.1186/1756-0500-4-28 11 0 0 6 "Humans|*Genome-Wide Association Study|*Tuberculosis|Mycobacterium tuberculosis|Pulmonary Tuberculosis|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Human Genetics" 12 MS4A12 22081019 Nat. Biotechnol. 2011 PMC3237928 10.1038/nbt.2038 245 1 20 16 "Humans|*Colon Cancer|Gene Expression Regulation, Neoplastic|HCT116 Cells|Adenocarcinoma|*Dissection|Cell Differentiation|*B-Lymphocytes|Gene Expression|Lineages, Cell|Single-Cell Analysis|KRT20 protein, human|Keratin-20|SLC26A3 protein, human|Sulfate Transporters|Chloride-Bicarbonate Antiporters" 12 PRAP1 21540836 Mol. Ther. 2011 PMC3149176 10.1038/mt.2011.80 2 2 1 55 "*Transgene|*Transfections|*Plasmids|Gene Transfer Techniques|Genetic Vectors|Gene Therapy|trichostatin A|Hydroxamic Acids|Promoter Regions, Genetic|Reporter Gene|HDAC2 protein, human|Histone Deacetylase 2|Green Fluorescent Proteins|Gene Expression|Cell Line, Tumor" 12 serpinb11 21849706 Biol. Reprod. 2011 10.1095/biolreprod.111.093526 4 2 0 15 "Humans|Female|Animals|Mice|Chickens|*Estrogens|Oviduct|Diethylstilbestrol|Estrogens, Non-Steroidal|Avian Proteins|mRNA|Serpins|Ovary|MicroRNAs|Ovarian Neoplasms|Cells, Epithelial|Organ Specificity" 12 SERPINI2 22110064 Invest. Ophthalmol. Vis. Sci. 2011 10.1167/iovs.10-5640 1 0 0 24 "Humans|*Refractive Error|Genetic Predisposition to Disease|Genome-Wide Association Study|Myopia|Polymorphism, Single Nucleotide|*European Continental Ancestry Group|*Ethnic Groups" 12 SLC43A3 21827714 BMC Med Genomics 2011 PMC3174875 10.1186/1755-8794-4-64 0 10 1 81 "Humans|*Lipopolysaccharides|*Inflammation|Monocytes|*Atherosclerosis|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation|RNA, Messenger|Transcriptome" 12 SNORD44 21914171 Breast Cancer Res. 2011 PMC3262198 10.1186/bcr2943 32 0 5 0 "Humans|*Up-Regulation|MicroRNAs|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|*Transcriptional Activation|Real-Time Polymerase Chain Reaction|Case-Control Studies" 12 SNORD44 21272993 Eur. Urol. 2011 10.1016/j.eururo.2011.01.004 75 0 8 0 "*RNA, Micro|*Cancer, Kidney|Renal Cell Carcinoma|Adenoma, Oxyphilic|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Diagnosis, Differential|Genetic Testing" 12 ADGB 20074184 J. Anim. Breed. Genet. 2010 10.1111/j.1439-0388.2008.00789.x 0 0 0 6 Female|Pregnancy|Sheep|Animals|Iran|*Phenotype|Weaning|Birth Weight|Weight Gain|Maternal Effects|*Biological Phenomena|Birth 12 calr3 21131354 J. Biol. Chem. 2010 PMC3037677 10.1074/jbc.M110.140152 39 1 5 22 "Male|Female|Humans|*Testis|*Sperm|*Fertility|Zona Pellucida|Sperm-Ovum Interactions|calmegin|*Molecular Chaperones|Infertility, Male|Sperm Motility|Calcium-Binding Proteins|Calnexin|Oviduct|ADAM Proteins|Membrane Glycoproteins|Germ Cell|Fallopian Tubes|Endoplasmic Reticulum" 12 calr3 20966425 J. Androl. 2010 10.2164/jandrol.110.010900 3 0 0 22 "Male|Female|Humans|Mice|Animals|Sperm-Ovum Interactions|Sperm|Zona Pellucida|Sperm Motility|calmegin|Calcium-Binding Proteins|Molecular Chaperone|Infertility, Male|Testis|ADAM Proteins|Oviduct|Membrane Glycoproteins|Fallopian Tubes|Mice, Knockout|SPESP1 protein, human|Carrier Proteins|Seminal Plasma Proteins|Izumo1 protein, mouse" 12 DNAH8 20544845 Genes Chromosomes Cancer 2010 PMC3398139 10.1002/gcc.20784 25 0 4 24 "Humans|*Gene Amplification|Lactoylglutathione Lyase|Gastric Cancers|Apoptosis|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Tumor Cells, Cultured|RNAi|RNA, Messenger|GLO1 protein, human" 12 FGD6 20170901 Am. J. Hum. Genet. 2010 PMC2833388 10.1016/j.ajhg.2010.02.002 66 0 4 74 "Humans|*Gene-Environment Interaction|Quantitative Trait Loci|Genome-Wide Association Study|Phenotype|Genotype|Polymorphism, Single Nucleotide|Genetic Variation" 12 GAS2L1 20537721 Psychiatry Res 2010 10.1016/j.psychres.2009.09.018 4 1 1 61 "Humans|*Astrocyte|*Schizophrenia|Gene Frequency|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Haplotype|Linkage Disequilibrium|Asian Continental Ancestry Group|Genome-Wide Association Study|Case-Control Studies|*Phosphoproteins|Chi-Square Distribution|PEA15 protein, human|Intracellular Signaling Peptides and Proteins|GAS2L1 protein, human|Microfilament Proteins|ENTPD4 protein, human" 12 KIAA1324 21102415 Mod. Pathol. 2010 PMC3058634 10.1038/modpathol.2010.211 17 7 2 54 "Female|Humans|*Ovary|*Peritoneum|Cystadenocarcinoma, Serous|Ovarian Neoplasms|Carcinoma, Ovarian Epithelial|Prognosis|*Receptors, Estrogen|Peritoneal Neoplasms|Endometrial Carcinomas|*Clustering|Immunohistochemistry|Disease-Free Survival|Cox Proportional Hazards Models|Gene Expression Regulation, Neoplastic|EIG121 protein, human|Membrane Proteins" 12 KIAA1324 21072319 Cell Death Dis 2010 PMC2976047 10.1038/cddis.2010.9 32 26 1 54 "Humans|*Cell Survival|*Autophagy|Lysosomes|Phagosomes|Endosomes|Microtubule-Associated Proteins|Vacuoles|Membrane Proteins|Plasma Membrane|*Gene Expression|Cell Death|HeLa Cells|Autophagosomes|*Estrogens|EIG121 protein, human" 12 LZIC 21073729 Proteome Sci 2010 PMC2996359 10.1186/1477-5956-8-56 16 4 0 155 "*Blood Platelets|*Thrombin|*Proteome|*Arachidonic Acid|Tandem Mass Spectrometry|Platelet Activation|Platelet Aggregation|PAGE, 2D|*Collagen|Hemostasis|Bleeding|SDS PAGE" 12 PRAP1 20674898 Fertil. Steril. 2010 10.1016/j.fertnstert.2010.06.034 14 0 1 55 "Mice|Female|Animals|*Implantation, Embryo|*Uterus|*Epithelium|Progesterone|Estradiol|mRNA|*Biomarkers|Proline" 12 PRAP1 20547205 Mol. Cell. Endocrinol. 2010 10.1016/j.mce.2010.06.003 4 4 1 55 "Pregnancy|Female|Humans|Mice|Rabbits|Animals|*Oestradiol|*Histone Deacetylase|*Embryo Implantation|Uterus|*Estrogens|Endometrium|Ovariectomy|TYRP1 protein, human|Membrane Glycoproteins|Epithelium|Histone Deacetylase Inhibitors|RNA, Messenger|Proline" 12 RASL11A 20168301 EMBO J. 2010 PMC2857460 10.1038/emboj.2010.16 8 0 2 8 "Mice|Animals|*rDNA|*Chromatin|transcription factor UBF|Pol1 Transcription Initiation Complex Proteins|RNA Polymerase I|Organizers, Nucleolar|Cell Nucleolus|Transcription, Genetic|Interphase|RNA, Ribosomal|Transcription Factors|DNA-Binding Proteins|Chromosomes|Cell Cycle|*ras Proteins" 12 serpinb11 20514468 Oncol. Rep. 2010 10.3892/or_00000852 15 0 1 15 "*Carcinoma, Squamous Cell|squamous cell carcinoma-related antigen|*Serpins|*Mouth Neoplasms|*Downregulation|Gene Expression Regulation, Neoplastic|Antigens, Neoplasm|Serine Protease Inhibitors|Gene Cluster|*Chromosome" 12 SLC25A43 21108393 Am. J. Med. Genet. A 2010 10.1002/ajmg.a.33743 12 0 2 49 "Male|Humans|*Intellectual Disability|*Speech|*Ubiquitin-Conjugating Enzymes|*Seizures|*Abnormalities, Skin|*Syndrome|Chromosome Deletion|Chromosomes, Human, X|Pedigree|Mutation|*Speech Disorders|Brazil|NKRF protein, human|Repressor Proteins|SLC25A43 protein, human|Tumor Suppressor Proteins" 12 WDR13 20662849 Clin. Genet. 2010 10.1111/j.1399-0004.2010.01496.x 6 0 1 110 "Male|Humans|Female|Child|Mental Retardation, X-Linked|Sex Chromosome Aberrations|Chromosomes, Human, X|Gene Duplication|Comparative Genomic Hybridization|Phenotype|Intellectual Disability|In Situ Hybridization, Fluorescence|*Cognition" 12 WDR13 20655035 Am. J. Hum. Genet. 2010 PMC2917707 10.1016/j.ajhg.2010.06.017 40 0 3 110 "Child|Humans|*DNA Copy Number Variations|*Intellectual Disability|Comparative Genomic Hybridization|Genes, X-Linked|Chromosomes, Human, X|Chromosome Duplication|X Chromosome Inactivation|Pedigree|Developmental Disabilities|*INDEL Mutation|Chromosome Mapping|Phenotype|Oligonucleotide Array|*Survey|Cohort Studies|PTCHD1 protein, human|Membrane Proteins" 12 xpo7 20503194 J. Cell. Biochem. 2010 PMC2930062 10.1002/jcb.22689 5 0 2 135 "Animals|RanGTP-binding protein 16|RanGTP-binding protein 17|*ran GTP-Binding Protein|Helix-Loop-Helix Domain|*Transcription Factors, General|Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|Cell Differentiation|Importin-beta|Protein Binding|Cell Line" 12 GAS2L1 19375645 Exp. Hematol. 2009 10.1016/j.exphem.2009.02.002 8 1 1 61 "Humans|*Thyroid Hormone Receptor|Cell Differentiation|Erythropoiesis|Erythroid Precursor Cells|*Cells, Erythroid|Transcription Factors|Triiodothyronine|Gene Expression|Cells, Cultured" 12 LZIC 19444910 Int. J. Cancer 2009 10.1002/ijc.24392 14 0 3 155 "Rats|Animals|Glycogen Synthase Kinase 3 beta|CTNNB1 protein, human|beta Catenin|Osteosarcoma|Wnt Proteins|*Gene Expression Profiling|DKK3 protein, human|Intercellular Signaling Peptides and Proteins|Cell Differentiation|Wnt beta-Catenin Signaling Pathway|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Phosphorylation|AKAP12 protein, human|A Kinase Anchor Proteins|Cell Proliferation|Cell Cycle Proteins" 12 MS4A12 19781065 Mol. Cancer 2009 PMC2759907 10.1186/1476-4598-8-77 8 12 1 16 "*CDX2 Transcription Factor|*Genes, Homeobox|*Calcium|CDX1 protein, human|Homeodomain Proteins|*Colon Cancer|Transactivator|Colon|Promoter Regions, Genetic|Transcription, Genetic|Transcription Factors|Chromatin Immunoprecipitation|Cell Differentiation|Protein Binding|Cell Line, Tumor|RNA, Messenger" 12 NOMO1 19175411 Exp. Dermatol. 2009 10.1111/j.1600-0625.2008.00821.x 1 0 0 54 "Humans|*Detergents|Cutaneous T Cell Lymphoma|*Membrane Proteins|mRNA|Neoplasm Proteins|*Subtractive Hybridization|Skin Neoplasms|Skin|*Dose Fractionation, Radiation|Plasma Membrane|Western Blotting|Cell Line, Tumor" 12 SERPINI2 19641524 Leukemia 2009 10.1038/leu.2009.144 6 3 0 24 "Humans|Adult|*Lymphoma, Mantle-Cell|*Leukemia, Lymphocytic, Chronic, B-Cell|*Gene Knockdown Techniques|SERPINI2 protein, human|Neoplasm Proteins|SMARCC2 protein, human|Transcription Factors|Gene Expression Regulation, Leukemic|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Nuclear Factor-Kappab|Serpins|CCDC50 protein, human|Intracellular Signaling Peptides and Proteins" 12 SERPINI2 19334046 J. Pathol. 2009 10.1002/path.2520 25 0 3 24 "Humans|*Transcriptome|*Carcinoma, Non-Small-Cell Lung|*Carcinoma, Squamous Cell|Lung Neoplasms|*Smoking|SERPINI2 protein, human|Neoplasm Proteins|Oligonucleotide Array Sequence Analysis|*Respiratory Mucosa|Gene Expression Regulation, Neoplastic|*Tobacco Smoking|Gene Expression Profiling|Bronchi|Up-Regulation|Cell Transformation, Neoplastic|Epithelium|Epithelial Cells|Downregulation" 12 ZPBP 19204925 Microsc. Res. Tech. 2009 10.1002/jemt.20696 8 0 0 18 Male|Mice|Animals|*Zona Pellucida|*Spermiogenesis|Acrosome|Spermatids|Spermatozoa|Acrosome Reaction|Spermatozoa Maturation|Fertilization|Glycoproteins 12 DNAH8 18567798 Mol. Cancer Res. 2008 PMC2693718 10.1158/1541-7786.MCR-07-2115 31 0 1 24 "Humans|Comparative Genomic Hybridization|*Osteosarcoma|Bone Neoplasms|Genes, cdc|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|Gene Amplification|Chromosome Mapping|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|Oncogenes|Clones|*Chromosome Structures|Gene Expression|Cell Cycle|PTK7 protein, human|Cell Adhesion Molecules|Receptor Protein-Tyrosine Kinases" 12 MS4A12 18451174 Cancer Res. 2008 10.1158/0008-5472.CAN-07-5768 22 1 1 16 "*Calcium Channel|Colon Cancers|Membrane Proteins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Colon|RNA, Small Interfering|Gene Silencing|Apoptosis|EGFR protein, human|Epidermal Growth Factor Receptor|RNA, Messenger|Cell Transformation, Neoplastic|Immunohistochemistry|*Cell Membrane Structures" 12 RBM19 19087264 BMC Dev. Biol. 2008 PMC2627835 10.1186/1471-213X-8-115 11 6 0 63 "Female|Pregnancy|Mice|Animals|*Embryonic Development|Morula|Blastocyst|Cell Nucleolus|Gene Expression Regulation, Developmental|Proteins" 12 SLC43A3 18483404 Arterioscler. Thromb. Vasc. Biol. 2008 10.1161/ATVBAHA.108.165738 44 0 4 81 "Oligonucleotide Array Sequence Analysis|Endothelial Cell|Neovascularization, Physiologic|*Microvasculature|Gene Expression Profiling|Pathological Angiogenesis|Endothelium, Vascular|Cells, Cultured" 12 TASP1 18398573 J. Neurooncol. 2008 10.1007/s11060-008-9579-4 38 0 1 65 "Humans|*Glioblastoma|*Oligonucleotide Array Sequence Analysis|*Transcriptome|*Real-Time PCR, Quantitative|Brain Neoplasms|*Brain|Gene Expression Profiling|STIM1 protein, human|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Immunohistochemistry|Prognosis|cDNA|Stromal Interaction Molecule 1|EEF1A1 protein, human|Peptide Elongation Factor 1|EMP3 protein, human" 12 TASP1 18395097 Gastroenterology 2008 10.1053/j.gastro.2008.01.027 14 6 1 65 "*Carcinoma, Hepatocellular|*Liver Neoplasms|Hepatocyte Nuclear Factor 4|*RNA Splicing|Promoter Regions, Genetic|Liver|Cell Differentiation|Gene Expression Regulation" 12 ZDHHC23 18421176 Exp. Anim. 2008 10.1538/expanim.57.135 0 0 0 21 "Rats|Animals|*Rat, OLETF|*Alleles|Diabetes Mellitus, Type 2|*Rats, Inbred F344|Hyperglycemia|Animals, Congenic|Obesity|Quantitative Trait Loci|Chromosome Mapping|Blood Glucose|Crosses, Genetic|Phenotype|Genotype" 12 ZPBP 18340633 Proteomics 2008 10.1002/pmic.200701020 37 0 4 18 "Male|Mice|Animals|*Proteome|*Chromatography, Liquid|Proteomics|*Tandem Mass Spectrometry|Electrophoresis, Gel, Two-Dimensional|*Sperm|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|zonadhesin|Membrane Proteins|Gene Expression Profiling|SPESP1 protein, mouse|Carrier Proteins|Seminal Plasma Proteins|ACRBP protein, mouse|Acrosome|Odf1 protein, mouse|Heat-Shock Proteins" 12 ADGB 18059651 N Z Vet J 2007 10.1080/00480169.2007.36788 2 0 0 6 "Female|Pregnancy|Horses|Animals|*Weaning|Animal Nutritional Physiological Phenomena|*Birth|Animals, Newborn|Animal Feed|Animal Husbandry|Weight Gain|New Zealand" 12 ANKRD30A 17967063 PLoS Genet. 2007 PMC2041996 10.1371/journal.pgen.0030181 145 6 7 4 12 calr3 17655857 J. Mol. Cell. Cardiol. 2007 10.1016/j.yjmcc.2007.06.009 28 3 3 22 "Humans|*Cardiomyopathy, Hypertrophic, Familial|*Genetic Screening|Sarcomere|Calsequestrin|Calmodulin|*Calcium, Dietary|Mutations|Phenotype|*Gene Expression Regulation|Cohort Studies|Australia" 12 GAS2L1 17330099 Leukemia 2007 10.1038/sj.leu.2404611 21 0 1 61 "Humans|*Myeloid Leukemias, Acute|Azacitidine|Decitabine|Myelodysplastic Syndrome|CpG Islands|Promoter Regions, Genetic|DNA Methylation|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Gene Expression Regulation, Leukemic|Histone Deacetylase Inhibitor|Hydroxamic Acids|Antimetabolites, Antineoplastic|CTNNA1 protein, human|alpha Catenin|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|EHD3 protein, human" 12 IRF2BPL 17627301 J. Clin. Invest. 2007 PMC1906733 10.1172/JCI31752 40 0 2 58 Animals|Female|Sexual Maturation|progonadoliberin I|Gonadotropin Releasing Hormone|*Neurosecretory Systems|Hypothalamus|*Reproduction|*Gene Expression Regulation|proenkephalin|Protein Precursors|Neurons|Neuroglia|preproenkephalin|Gene Expression|Nuclear Protein 12 KIAA1324 17475571 Gene Expr. Patterns 2007 10.1016/j.modgep.2007.03.004 2 0 0 54 "Animals|*Xenopus laevis|Gastrula|Xenopus Proteins|In Situ Hybridization|Embryo, Nonmammalian|Neural Plate|Blastula|Amino Acid Sequence|Gene Expression Regulation, Developmental|Mesoderm|Sequence Homology, Amino Acid|Central Nervous System|RNA, Messenger|Estrogens" 12 LZIC 17470402 Cell Biol. Int. 2007 10.1016/j.cellbi.2007.03.003 7 0 1 155 "Animals|*Wnt Signaling Pathway|Phylogeny|Glycogen Synthase Kinase 3|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Frizzled Receptors|Transcription Factors, LEF|RHOA protein, human|rhoA GTP-Binding Protein|rho GTPases|Cell Differentiation|Cell Nucleus|Embryogenesis" 12 LZIC 17243164 Genes Chromosomes Cancer 2007 10.1002/gcc.20413 2 0 0 155 "Humans|*Chromosomes, Human, Pair 1|*Wilms Tumor|Loss of Heterozygosity|Microsatellite Markers|Cancer of the Kidney|Chromosome Deletion|Neuroblastoma|Chromosome Mapping|Rhabdoid Tumor|*Chromosome Structures" 12 NOMO1 17244794 J. Med. Microbiol. 2007 10.1099/jmm.0.46882-0 28 15 4 54 "Humans|TLR2 protein, human|*Toll-Like Receptor 2|CXCL8 protein, human|*Interleukin-8|*Helicobacter pylori|*Monocytes|*Chaperonin 60|Nuclear Factor-Kappab|p38 Mitogen-Activated Protein Kinases|JNK Mitogen-Activated Protein Kinases|Extracellular Signal Regulated Kinases|SB 203580|Imidazoles|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Mitogen-Activated Protein Kinase Kinases|Pyridines|Toll-Like Receptor" 12 RASL11A 17628721 Biochim. Biophys. Acta 2007 10.1016/j.bbaexp.2007.05.005 8 3 0 8 "Humans|Pregnancy|Female|Exons|TATA Box|Base Sequence|Introns|Promoter Regions, Genetic|*Genomics|Amino Acid Sequence|Cloning, Molecular|Transcription Factors|Transcription, Genetic|DNA, Complementary|mRNA|Binding Sites|Chromosome Mapping|Transfection" 12 serpinb11 17562709 J. Biol. Chem. 2007 10.1074/jbc.M703182200 10 1 0 15 "Humans|Animals|Mice|*Serpins|*Polymorphism, Single Nucleotide|Sequences, Amino Acid|Serine Proteinase Inhibitors|Binding Sites|Protein Conformation|Protein Structure, Secondary|Leukocyte Elastase|Trypsin|Kinetics|*Cytoplasm" 12 SERPINI2 17668148 Cell. Mol. Life Sci. 2007 10.1007/s00018-007-7157-0 12 0 0 24 *Serpins|*Secretory Pathway|Amino Acid Sequence|Sequence Alignment|Serine Protease Inhibitors 12 xpo7 17764892 Genomics 2007 PMC2205530 10.1016/j.ygeno.2007.06.010 4 0 0 135 "Humans|Male|Animals|Spermatids|Spermatogenesis|Spermatocytes|Testis|Seminiferous Tubule|cDNA|Amino Acid Sequence|Base Sequence|Blotting, Northern|Proteins|mRNA|Gene Expression Profiling|In Situ Hybridization|Gene Expression Regulation, Developmental" 12 ZDHHC23 17899403 J. Mol. Histol. 2007 10.1007/s10735-007-9144-z 1 0 0 21 "Rats|Animals|*Ganglia, Spinal|*Pain|Hyperalgesia|*Peripheral Nervous System Diseases|Rats, Sprague-Dawley|Nociceptive Neurons|*Gene Expression Regulation|Pain Threshold|NOS1 protein, human|nNOS Enzyme|Horn, Dorsal|Nitric Oxide Synthase|Neurons|Up-Regulation" 12 ZDHHC23 17873365 J. Mol. Neurosci. 2007 10.1007/s12031-007-0035-2 0 0 0 21 "United States|Rats|Animals|*Axotomy|NOS1 protein, human|Neuronal Nitric Oxide Synthase|Nerve, Sciatic|Ganglia, Dorsal Root|In Situ Hybridization|Binding Proteins|Nerve Regeneration|*Nerve Tissue|Neurons|Spinal Cord|mRNA|Synaptic Membrane|Postsynaptic Density Protein 95|*Gene Expression|Nitric Oxide" 12 ZPBP 17664285 Mol. Cell. Biol. 2007 PMC2099232 10.1128/MCB.01029-07 64 1 3 18 Humans|Male|Mice|Swine|Animals|*Acrosome|*Zona Pellucida|Phylogeny|Sperm Motility|*Spermatozoon|Sperm-Egg Interactions|*Spermiogenesis|Oocyte|Testes|Carrier Proteins|Membrane Proteins|Amino Acid Sequence|*Morphogenesis 12 ANKRD30A 17158753 Endocr. Relat. Cancer 2006 10.1677/ERC-06-0001 82 0 5 4 12 GAS2L1 16846370 Stem Cells Dev. 2006 10.1089/scd.2006.15.315 12 0 1 61 "Humans|*Human Embryonic Stem Cells|*Embryonic Stem Cells|Transcription Factors|Homeodomain Proteins|Nanog Homeobox Protein|Octamer Transcription Factor-3|HMGB Proteins|SOXB1 Transcription Factors|*Cell Line|Transcription, Genetic|Cell Differentiation|Gene Expression Regulation, Developmental|Embryo, Mammalian|Promoter Regions, Genetic|Protein Binding|Genes, Homeobox|RNA|GAS2L1 protein, human" 12 LZIC 17044048 Genes Chromosomes Cancer 2006 10.1002/gcc.20387 11 0 1 155 "*Neuroblastoma|Genes, Tumor Suppressor|Loss of Heterozygosity|Genes, myc|Chromosome Deletion|*Chromosome Structures|Gene Expression|RNA, Messenger" 12 RASL11A 16956712 Eur. Urol. 2006 10.1016/j.eururo.2006.08.008 25 8 1 8 "Humans|Male|*CpG Islands|*Cyclooxygenase 2|*Prognosis|Neoplasm Recurrence, Local|kallikrein-related peptidase 3, human|Prostate Specific Antigen|*Prostatectomy|*DNA Methylation|*Prostate|*Seminal Vesicles|retinoic acid receptor beta|*Receptors, Retinoic Acid|Prostate Cancer|Glutathione S-Transferase pi|*Receptor, Endothelin B|PTGS2 protein, human|EDNRB protein, human" 12 SLC25A43 16949250 Genomics 2006 10.1016/j.ygeno.2006.06.016 57 0 3 49 "Animals|Humans|Rats|Mice|*Mitochondria|Mitochondrial Membrane Transport Proteins|Membrane, Mitochondrial|*Central Nervous System|Membrane Transport Proteins|Phylogeny|Biological Transport|Multigene Family|Saccharomyces cerevisiae|Brain|SLC25A32 protein, human|SLC25A39 protein, human|Slc25a38 protein, human|SLC25A43 protein, human|Tumor Suppressor Proteins|SLC25A46 protein, human|Mitochondrial Proteins|Phosphate Transport Proteins" 12 ANKRD30A 16364570 Gene 2005 10.1016/j.gene.2005.07.045 21 0 0 4 "Humans|Mice|Animals|*Ankyrin Repeat|Sequence Alignment|Gene Duplication|ANKRD26 protein, human|Nuclear Proteins|Multigene Family|Primate|Genome, Human|Phylogeny|Computational Biology|Genes, Regulator|*Protein Domains|Ankrd26 protein, mouse|DNA-Binding Proteins|Transcription Factors" 12 DNAH8 16054618 Dev. Biol. 2005 10.1016/j.ydbio.2005.06.002 4 0 0 24 "Humans|Male|Mice|Animals|*Sperm Tail|*Dyneins|t-Complex Genome Region|*Protein Isoforms|Male Sterility|Microtubule-Associated Proteins|Sperm|Sperm Motility|Amino Acid Sequence|Nuclear Proteins|Base Sequence|Testis|Intracellular Signaling Peptides and Proteins|Homozygote|DNA, Complementary|Sequence Homology, Amino Acid|Haplotype|Ubiquitin-Protein Ligases" 12 KIAA1324 16322283 Clin. Cancer Res. 2005 10.1158/1078-0432.CCR-05-1189 12 1 1 54 "Humans|Female|Endometrial Cancer|Endometrial Hyperplasia|Carcinoma, Endometrioid|*Uterine Neoplasms|*Estrogens|Cystadenocarcinoma, Serous|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Hormone Replacement Therapy|*Regulatory Gene|RNA, Messenger|Gene Expression|EIG121 protein, human|Membrane Proteins" 12 LZIC 16163269 Mol. Vis. 2005 5 0 0 155 "Humans|Corneal Dystrophy, Crystalline, of Schnyder|*Corneal Dystrophies, Hereditary|DNA Mutational Analysis|Pedigree|Mutation|Dimethylallyltranstransferase|Polymerase Chain Reaction|Polymorphism, Single Nucleotide" 12 LZIC 15932753 Dev. Biol. 2005 10.1016/j.ydbio.2005.04.026 6 2 1 155 "Animals|Humans|*Zebrafish|CTNNB1 protein, human|beta Catenin|Zebrafish Proteins|Transcription Factors|DNA-Binding Proteins|Trans-Activators|Wnt Proteins|Intracellular Signaling Peptides and Proteins|Xenopus Proteins|Amino Acid Sequence|Gene Expression Regulation, Developmental|*Cell Survival|Wnt Pathway" 12 RBM19 16027046 Gene Expr. Patterns 2005 10.1016/j.modgep.2005.05.001 7 0 1 63 Humans|Adult|Caco-2 Cells|*Progenitor Cells|*Intestinal Epithelium|*Cell Nucleolus|nucleophosmin|Nucleolar Proteins|Cell Differentiation|phosphoprotein C23|Phosphoproteins|Cell Proliferation|Intestine 12 SERPINI2 16184191 PLoS Genet. 2005 PMC1231717 10.1371/journal.pgen.0010038 5 4 1 24 "Mice|Animals|SERPINI2 protein, human|*Serpins|*Acinar Cells|In Situ Hybridization, Fluorescence|*Insufficiency, Pancreatic|*Pancreatic Diseases|*Neoplasm Proteins|Pancreas, Exocrine|Mice, Transgenic|Pancreas|*Apoptosis|Phenotype|Cystic Fibrosis|Mutation|Gene Expression|Disease Models, Animal" 12 WDR13 16094675 Mol. Reprod. Dev. 2005 10.1002/mrd.20362 0 0 2 110 "Male|Mice|Animals|*Testis|Amino Acid Sequence|WDR13 protein, mouse|Nuclear Proteins|In Situ Hybridization|Base Sequence|Sequence Alignment|Splicings, Alternative|Genome|Introns|Sequence Homology, Amino Acid|Chromosome Mapping|Blotting, Northern|Cloning, Molecular|Phylogeny|Cell Nucleus" 12 KIAA1324 14767521 Oncol. Rep. 2004 2 0 0 54 "Humans|Tumor Cell Lines|*Carcinoma|cDNA|mRNA|*RNA Splicing|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Cell Proliferation|Cluster Analysis" 12 RASL11A 15033445 Biochem. Biophys. Res. Commun. 2004 10.1016/j.bbrc.2004.02.091 11 0 0 8 "Humans|Male|*Prostate Cancer|Prostate|*Downregulation|Northern Blot|Amino Acid Sequence|Genes, Tumor Suppressor|Base Sequence|Small GTPases|RNA, Messenger|Cloning, Molecular|gephyrin|Membrane Proteins|Genome Mapping|Sequence Homology, Amino Acid" 12 ZDHHC23 15105416 J. Biol. Chem. 2004 10.1074/jbc.M401471200 15 5 1 21 "Animals|Rats|NOS1 protein, human|*Neuronal Nitric Oxide Synthase|*Synaptic Membranes|*Neurons|Nerve Tissue Proteins|Carrier Proteins|Disks Large Homolog 4 Protein|Nitric Oxide Synthase|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Protein Binding|Amino Acid Sequence|Brain|Signal Transduction|mRNA" 12 ACTL7A 12840782 Am. J. Hum. Genet. 2003 PMC1180380 10.1086/377184 6 0 0 4 "Humans|Adolescent|Hypertensive Nephropathy|*African Americans|*Hypertension, Renal|*Nephritis|Lod Score|Genetic Linkage|Focal Segmental Glomerulosclerosis|Pedigree|Phenotype|Chromosome Mapping|Haplotypes|Genes, Dominant|Hypertension|*Chromosome Structures|Proteinuria|End Stage Renal Disease|ACTL7A protein, human|Actins" 12 ACTL7A 12672658 Biol. Reprod. 2003 10.1095/biolreprod.103.015867 13 0 1 4 "Male|Mice|Animals|*Actins|*Haploidy|Spermiogenesis|*Cytoplasm|*Germ Cells|Sequences, Amino Acid|*Cell Nucleus|Spermatozoa|Testis|cDNA|Base Sequence|mRNA|cDNA Library|Cloning, Molecular" 12 GAS2L1 12584248 J. Cell. Sci. 2003 10.1242/jcs.00272 20 1 3 61 "Male|Humans|Mice|Animals|*Chromosome 17|*Microfilaments|*Microtubules|Actin|Cytoskeleton|Microfilament Proteins|Microtubule-Associated Proteins|Cytoskeletal Proteins|Amino Acid Sequence|Protein Binding|TYRP1 protein, human|*Membrane Glycoproteins|Protein Structure, Tertiary|Protein Isoforms|cDNA|Splicings, Alternative|mRNA|GAS2 protein, human" 12 WDR13 12659815 Genomics 2003 10.1016/s0888-7543(02)00036-8 8 4 2 110 "Male|Animals|Humans|In Situ Hybridization, Fluorescence|*Proteins|Introns|Exons|Amino Acid Sequence|Sequence Alignment|Base Sequence|Chromosome Mapping|*WD Repeat|DNA, Complementary|Open Reading Frame|Cloning, Molecular|Sequence Analysis, DNA|Sequence Homology, Amino Acid|Alternative Splicing|Phylogeny|Promoter Regions, Genetic|5' UTR" 12 ZPBP 12883658 Int. J. Mol. Med. 2003 7 0 0 18 12 DNAH8 12297094 Dev. Biol. 2002 10.1006/dbio.2002.0769 5 0 0 24 "Humans|Male|*Dyneins|*Testis|Sperm Motility|Amino Acid Sequence|Base Sequence|Isoforms|Male Sterility|mRNA|Chlamydomonas|5' Untranslated Region|Chromosome Mapping|Homozygote|Sequence Homology, Amino Acid" 12 LZIC 11712074 Int. J. Mol. Med. 2001 10.3892/ijmm.8.6.611 5 5 0 155 "Humans|*Leucine Zippers|*Cloning, Molecular|Exons|Base Sequence|Amino Acid Sequence|mRNA|DNA, Complementary|Blotting, Northern|Chromosome Mapping|Introns|Genome, Human|Sequence Homology, Amino Acid|CTNNB1 protein, human|beta Catenin|Up-Regulation|HL-60 Cells" 12 MS4A12 11486273 Immunogenetics 2001 10.1007/s002510100339 33 0 1 16 "Humans|Mice|Animals|*Gene Cluster|Cell Surface Proteins|Amino Acid Sequence|Intron|Base Sequence|Exons|*Chromosome Structures|Sequence Homology, Amino Acid|Sequence Alignment|Cloning, Molecular|Genes, Regulator|Carrier Proteins|*Morphogenesis|DNA, Complementary|Antigens, CD20|Cell Membrane|Receptors, IgE" 12 MS4A12 11401424 Genomics 2001 10.1006/geno.2000.6472 38 0 0 16 "Mice|Humans|Animals|*Antigens, CD20|Cell Surface Proteins|Amino Acid Sequence|Chromosome Mapping|Cloning, Molecular|Sequence Homology, Amino Acid|Receptors, IgE|Antigens, CD|Cell Membrane|Cell Cycle Proteins|DNA, Complementary|Multigene Family|RNA, Messenger" 12 IRF2BPL 11095982 Biochem. 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Inorg. Biochem. 2020 10.1016/j.jinorgbio.2020.111134 0 0 0 7399 "*Thiosemicarbazones|*Copper|Coordination Complexes|Antineoplastic Agents|Reactive Oxygen Species|Apoptosis|Cell Proliferation|Tumors|Ligands|Models, Molecular" 11 curcumin 32673649 Ann Hepatol 2020 10.1016/j.aohep.2020.05.006 0 0 0 7399 *Curcumin|*Hepatic Stellate Cells|Carbon Tetrachloride|*Downregulation|Liver Cirrhosis|NF-kappa B|Signal Transduction|Transforming Growth Factor beta1|Liver 11 curcumin 32671790 Adv. Exp. Med. Biol. 2020 10.1007/978-981-15-4272-5_55 0 0 0 7399 *Cardiovascular Diseases|*Natural Products|Endothelial Cells|*Autophagy|Cardiomyocytes|Myocardium|Myocardial Reperfusion Injury|Heart Failure|Myocardial Ischemia|Organelles|Curcumin|epigallocatechin gallate|Catechin 11 curcumin 32671789 Adv. Exp. Med. Biol. 2020 10.1007/978-981-15-4272-5_54 0 0 0 7399 *Neurodegenerative Diseases|*Natural Products|*Autophagy|Alzheimer Disease|Huntington Disease|Neurons|Parkinson Disease|Resveratrol|Curcumin|Inclusion Bodies 11 curcumin 32668325 Life Sci. 2020 10.1016/j.lfs.2020.118091 0 0 0 7399 "Rats|Humans|Animals|*Curcumin|*Diabetes Mellitus, Experimental|*Platelet Rich Plasma|*Adiposity|Wound Healing|*Obesity|Adipose Tissue|Neovascularization, Physiologic|Adipocytes|*Transplants|*B Cells|Stem Cells" 11 curcumin 32666415 J. Mol. Neurosci. 2020 10.1007/s12031-020-01639-z 0 0 0 7399 "*Temozolomide|*Glioblastoma|*Wnt Signaling Pathway|*Curcumin|Brain Neoplasms|Dacarbazine|Autophagy|Antineoplastic Agents, Alkylating|Apoptosis|Beclin 1|Cell Line, Tumor|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Cell Survival|Xenograft Model Antitumor Assays|Apoptosis Regulatory Proteins|*Combined Modality Therapy" 11 curcumin 32664425 Molecules 2020 10.3390/molecules25143165 0 0 0 7399 11 curcumin 32663009 ACS Chem Neurosci 2020 10.1021/acschemneuro.0c00363 0 0 0 7399 "NFE2L2 protein, human|*NF-E2-Related Factor 2|*Parkinson Disease|*Glycogen Synthase Kinase 3|*Curcumin|diethyl fumarate|*GA-Binding Protein Transcription Factor|*Fumarates|Oxidative Stress|Antioxidant Effects|Alzheimer Disease|Reactive Oxygen Species|Signal Transduction|Hybrid-B|*Plasminogen Activators|Downregulation" 11 curcumin 32662804 J Mater Chem B 2020 10.1039/d0tb01101k 0 0 0 7399 "Humans|Animals|Mice|*Curcumin|*Micelles|Neurodegenerative Diseases|*Plaque, Amyloid|Alzheimer Disease|Amyloid beta-Peptides|*Retina|Transgenic Mouse|Disease Models, Animal|Brain|Retinal Diseases|*Optical Imaging|Memory Disorders" 11 curcumin 32659650 Colloids Surf B Biointerfaces 2020 10.1016/j.colsurfb.2020.111250 0 0 0 7399 "*Poloxamer|*Micelles|*Curcumin|Solubility|*Water|Excipients|Calorimetry, Differential Scanning|Solvents|Temperature|Polymer|Dimethylsulphoxide" 11 curcumin 32658314 Phytother Res 2020 10.1002/ptr.6784 0 0 0 7399 "*Tumor Microenvironment|Endothelial Cells|Tumor|Macrophages|Myeloid-Derived Suppressor Cells|Anticancer Agents|Fibroblasts|*Survey|Silibinin|*Plants, Medicinal" 11 FAM136A 32251013 Ear Hear 2020 10.1097/AUD.0000000000000878 0 0 0 96 "*Meniere Disease|Hearing Loss, Sensorineural|Tinnitus|Pedigree|Genetic Heterogeneity|Deafness" 11 FAM136A 32098576 Bioengineered 2020 PMC7051133 10.1080/21655979.2020.1735611 0 0 0 96 "Humans|*Lung Adenocarcinoma|Lung Cancer|Lymphatic Metastasis|Carcinoma, Non-Small-Cell Lung|Adenocarcinoma|Neoplasm Staging|Prognosis|Lymph Nodes|Immunohistochemistry" 11 FAM136A 32038468 Front Neurol 2020 PMC6987317 10.3389/fneur.2019.01424 0 0 0 96 11 FAM83G 32570757 Molecules 2020 10.3390/molecules25122810 0 0 0 143 "Cricetinae|Animals|Cricetulus|CHO Cells|Phosphorylation|HSPB1 protein, human|Heat Shock Protein 27|*Apoptosis|Intracellular Signaling Peptides and Proteins|protein kinase D|Protein Kinase C|p38 Mitogen-Activated Protein Kinases|Heat-Shock Proteins|HepG2 Cells" 11 FCRL6 32117244 Front Immunol 2020 PMC7033751 10.3389/fimmu.2020.00082 0 0 0 6 "*Precursor Cells, B-Lymphoid|*Antibodies|B-Lymphocyte Subsets|B Cells|Immunoglobulin Heavy Chains|Cell Differentiation|Self-Antigens|Fc Receptor" 11 FIBCD1 32614476 Scand. 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Funct. 2020 10.1247/csf.20028 0 0 0 45 "*Axon Initial Segment|Autism Spectrum Disorder|Proteomics|Axons|Neurons|Hippocampus|Ankyrins|Cells, Cultured|Epilepsy" 11 IQCG 32241839 Haematologica 2020 10.3324/haematol.2020.246629 0 0 0 22 "Humans|*Anemia, Diamond-Blackfan|*Genotype-Phenotype Association|Ribosomal Protein|Phenotype|Craniofacial Abnormalities|Mutation|Gene Deletion|Base Sequence" 11 KLHL14 32233603 Math Biosci Eng 2020 10.3934/mbe.2020089 0 0 0 34 "Humans|Female|*Endometrial Cancer|Ovarian Cancer|Carcinoma, Ovarian Epithelial|*Ovary|Prognosis|*Endometrium|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Kaplan-Meier Analysis|*Genes, Regulator|Up-Regulation" 11 KLHL14 32144311 Sci Rep 2020 PMC7060278 10.1038/s41598-020-61017-y 0 0 0 34 "*Epithelial-Mesenchymal Transition|*Transcriptome|lysophosphatidic acid|*Lysophospholipids|*Transcription Factors|Cells, Epithelial|*Genes, Regulator|Cell Line, Tumor|Signal Transduction" 11 KLHL14 32127472 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7084139 10.1073/pnas.1921187117 1 0 0 34 "*Signal Transduction|CD79 Antigens|Receptors, Antigen, B-Cell|Agammaglobulinaemia Tyrosine Kinase|Pyrazoles|Pyrimidines|Myeloid Differentiation Factor 88|Protein-Tyrosine Kinases|Lymphoma, Large B-Cell, Diffuse|NF-kappa B|Cell Line, Tumor|*Transcription Factors" 11 MAATS1 32161152 J. Med. Genet. 2020 10.1136/jmedgenet-2019-106775 0 0 0 14 "Humans|Male|Sperm Motility|Infertility, Male|Sperm Tail|Sperm|Axoneme|Asthenozoospermia|Whole Exome Sequencing|Flagella|Dyneins|Phenotype|Multiple Abnormalities|Mutation" 11 MAMDC2 32226304 Int. J. Biol. Sci. 2020 PMC7097924 10.7150/ijbs.42556 0 0 0 11 "Chlorocebus aethiops|Animals|*Herpesvirus 1, Human|*RNA, Long Noncoding|*Active Transport, Cell Nucleus|Gene Expression Regulation, Viral|Immediate-Early Proteins|Genes, Immediate-Early|Vero Cells|Cell Line|*B-Lymphocytes" 11 MAMDC2 31902979 Bioinformation 2020 PMC6936658 10.6026/97320630015799 0 0 0 11 "Humans|Female|Male|*Peroxisome Proliferator-Activated Receptors|Early Detection of Cancer|*Carcinoma, Ductal, Breast|Ductal Carcinoma In Situ|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Signal Transduction|Disease Progression|SFRP1 protein, human|Intercellular Signaling Peptides and Proteins|Membrane Proteins|Profile, Gene Expression|*Breast Neoplasms|RBP4 protein, human|Retinol-Binding Proteins, Plasma" 11 MFSD12 32385594 Int. J. 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Cell. Endocrinol. 2020 10.1016/j.mce.2020.110867 0 0 0 8 "andrographolide|*Liver|Hepatocyte Nuclear Factor 4|IGBP1 protein, human|*Intracellular Signaling Peptides and Proteins|*Diterpenes|PPARGC1A protein, human|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Gluconeogenesis|Hepatocytes|Glucose-6-Phosphatase|Downregulation|Lipoproteins, VLDL|Promoter Regions, Genetic|Heat-Shock Proteins|Phosphoenolpyruvate Carboxykinase (ATP)|Cells, Cultured" 11 PLA2G12B 32353589 Pharmacol. 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Sci. 2020 10.1016/j.psj.2019.12.036 0 0 0 5 Female|Humans|Animals|Child|*Chickens|*RNA|*Ovary|*Liver|Transcriptome|Lipid Metabolism|Gene Ontology|Gene Expression Profiling|Genomes|*Ovariectomy 11 TENM2 32493207 BMC Genet. 2020 PMC7271470 10.1186/s12863-020-00862-2 0 0 0 25 "Animals|*Chickens|*Tibia|*RNA-Seq|Poultry Diseases|*Osteomyelitis|Housing, Animal|Lameness, Animal|Osteochondrosis|*Bacteria|Necrosis|Bacterial Infections|*Whole Exome Sequencing|Femur|Chondrocytes|*Gene Expression" 11 TM2D3 32581363 Nature 2020 10.1038/s41586-020-2430-6 0 0 0 31 "*Multifactorial Inheritance|Loss of Heterozygosity|Chromosome Aberrations|Alleles|Polymorphism, Single Nucleotide|Hematologic Neoplasms" 11 CDH20 31612017 Oncol Lett 2019 PMC6781611 10.3892/ol.2019.10882 1 0 0 17 "Humans|Female|*Papilloma, Choroid Plexus|*Protons|Choroid Plexus Carcinoma|*Choroid Plexus Neoplasms|*DNA|*Sequencing, Next-Generation|Carcinoma|*Brain|Allele|Genes, Regulator|Mutation|Frameshift Mutation|*Glioma|Sequence Analysis, DNA|Kingdom of Saudi Arabia|STK36 protein, human|Protein-Serine-Threonine Kinases" 11 CEACAM16 31249509 Front Mol Neurosci 2019 PMC6582249 10.3389/fnmol.2019.00147 0 0 0 3 "*Tectorial Membrane|Otoacoustic Emissions, Spontaneous|Evoked Potentials, Auditory, Brain Stem|Hair Cells, Auditory, Outer|Auditory Threshold|Acoustic Stimulation|Extracellular Matrix Proteins|Mutations|GPI-Linked Proteins" 11 CLYBL 31066204 Biotechnol J 2019 10.1002/biot.201900036 2 0 0 323 "*Gene Editing|*Clustered Regularly Interspaced Short Palindromic Repeats|*CRISPR-Cas Systems|*DNA, Fungal|Guide RNA|Cas9 Protein|Endonucleases|Homologous Recombination|*Yeast, Dried|Genome" 11 CLYBL 31062447 J. 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Med. 2019 PMC6888979 10.1084/jem.20182244 0 0 0 77 "Animals|*Mycobiome|*Fungi|Dysbiosis|Gastrointestinal Microbiome|Microbial Interactions|Bacteria|Host Microbiota Interactions|Intestines|Chitin|*Receptors, Fibrinogen|Inflammation" 11 Fibin 31752878 Environ Health 2019 PMC6868717 10.1186/s12940-019-0535-x 1 0 0 13 "Pregnancy|Humans|Female|Child|*Arsenic|*Cohort Studies|New Hampshire|*Transcriptome|Maternal Exposure|Fetal Growth|*Birth|Birth Weight|Placenta|*Transcriptome Analysis|Prenatal Exposure Delayed Effects|Environmental Pollutants|Epigenesis, Genetic|DNA Methylation" 11 gimap7 31748878 Pathol. Oncol. 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Genet. 2019 1 0 0 88 "Child|Humans|*Chromosome Disorders|Deafness, Autosomal Recessive 22|*Hearing Loss, Sensorineural|Chromosome Deletion|Comparative Genomic Hybridization|Developmental Disabilities|Chromosome Aberrations|Phenotype" 11 IGSF9B 31015763 Onco Targets Ther 2019 PMC6446988 10.2147/OTT.S193808 1 0 0 45 "*Carcinoma, Renal Cell|*miRNA|*Kidney Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Cluster Analysis" 11 IQCG 31749837 Front Genet 2019 PMC6842931 10.3389/fgene.2019.01053 0 0 0 22 Male|Cattle|Animals|Humans|*Genome-Wide Association Study|*Semen|Semen Analysis|Sperm Motility|Sperm Count|*Phenotype|Breeding|Genotypes|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Sperm|*Bodily Secretions|Genomics|*Body Fluids|China 11 KLHL14 31558562 Cancer Res. 2019 10.1158/0008-5472.CAN-19-0039 3 0 0 34 11 LRP11 31865764 J Drug Target 2019 10.1080/1061186X.2019.1687710 0 0 0 21 "Humans|Male|CD274 protein, human|*B7-H1 Antigen|*Prostate Cancer|Signal Transduction|Up-Regulation|*Catenins|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Immunotherapy|Jurkat Cell|Transcriptional Activation" 11 LRP11 31507330 Cancer Manag Res 2019 PMC6719843 10.2147/CMAR.S211912 0 0 0 21 "Humans|Female|*Uterine Cervical Neoplasms|Cervical Intraepithelial Neoplasia|Cervix Uteri|Cyclin-Dependent Kinase Inhibitor p16|Immunohistochemistry|*Low Density Lipoprotein Receptor-Related Protein-1|Cell Proliferation|Cell Line, Tumor|*Carcinogens" 11 MAATS1 31446181 Clin. 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Anim. 2019 PMC7220707 10.1538/expanim.19-0042 0 0 0 11 "Humans|Male|Mice|Animals|*mRNA|*Testis|*Carcinoma, Squamous Cell|*Mouth Neoplasms|Piwi-Interacting RNA|Carcinogenesis|Downregulation" 11 MFSD12 31635058 Genes (Basel) 2019 PMC6827053 10.3390/genes10100826 0 0 0 25 Horses|Animals|Genome-Wide Association Study|*Mushroom|*Frameshift Mutation|Phenotype|Genotype|*Color 11 MFSD12 31315583 BMC Genet. 2019 PMC6637524 10.1186/s12863-019-0765-5 2 0 0 25 "Humans|*Genome-Wide Association Study|*Skin Pigmentation|Eye Color|Hair Color|Genotype|European Continental Ancestry Group|Polymorphism, Single Nucleotide|Phenotype" 11 MFSD12 31117290 Genes (Basel) 2019 PMC6562630 10.3390/genes10050386 3 0 0 25 "Dogs|Animals|Genome-Wide Association Study|Hair Color|phaeomelanin|Melanins|*Mutation, Missense|Skin Pigmentation|Breeding" 11 MFSD12 31038119 Med Sci (Paris) 2019 10.1051/medsci/2019064 0 0 0 25 "Humans|*Skin Pigmentation|Asian|Gene Frequency|European Continental Ancestry Group|Genotype|Haplotypes|Polymorphism, Single Nucleotide|Membrane Transport Proteins|Antiporters|Ethnic Groups|Latino" 11 MFSD12 30664655 Nat Commun 2019 PMC6341102 10.1038/s41467-018-08147-0 10 0 0 25 "Humans|*Genome-Wide Association Study|*Skin Pigmentation|Gene Frequency|European Continental Ancestry Group|Eye Color|Asians|Alleles|Selection, Genetic|Polymorphism, Single Nucleotide|Ethnic Groups|Membrane Transport Proteins|*Pigmentation Disorders|East Asia" 11 NBEAL1 31681433 Front Genet 2019 PMC6813924 10.3389/fgene.2019.01005 2 0 0 21 "Humans|Female|*Whole Exome Sequencing|*Exome|Hereditary Breast and Ovarian Cancer Syndrome|BRCA2 Protein|Germ-Line Mutation|Breast Cancer, Familial|Breast Cancer|Genetic Predisposition to Disease|Ovarian Neoplasms|High-Throughput Nucleotide Sequencing" 11 NBEAL1 31430377 Brain 2019 PMC6763741 10.1093/brain/awz233 2 0 0 21 "*Genome-Wide Association Study|Brain Ischemia|Stroke|Endothelial Cells|*Cerebral Small Vessel Disease|Cerebral Hemorrhage|Cerebral Amyloid Angiopathy|Brain|COL4A2 protein, human|Collagen Type IV|Genetic Testing" 11 NBEAL1 30865299 Cancer 2019 PMC6541501 10.1002/cncr.32020 1 0 0 21 "Humans|European Continental Ancestry Group|Gene Frequency|African Americans|*Cancer|Hispanic Americans|*Mutations|Genetics, Population|Ethnic Groups|Asian Continental Ancestry Group|Polymorphism, Single Nucleotide|*Gene Expression|*Cell Lines" 11 OTOGL 31465999 iScience 2019 PMC6718828 10.1016/j.isci.2019.08.016 2 2 0 2 "Humans|Animals|*Interferon-alpha|*Chiroptera|*B Virus|*Transcriptome|IFNL3 protein, human|Antiviral Agents|Interferon-beta|Immunity, Innate|Tetherin|Base Sequence" 11 PDZD8 31782998 Am. 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Sci. 2019 10.1042/CS20181110 0 0 0 8 "Humans|*Glomerulonephritis, Membranous|*Lipid Metabolism|*Gene Expression Profiling|*Genome|*Microarray Analysis|Gene Regulatory Networks|Transcriptome|Genomics|APOA1 protein, human|Apolipoprotein A1|CETP protein, human|Cholesteryl Ester Transfer Protein" 11 PLA2G12B 30922124 FASEB J. 2019 10.1096/fj.201802704R 0 1 0 8 "Mice|Animals|low density lipoprotein triglyceride|*Triglycerides|*Liver|*Lipid Metabolism|Lipoproteins, VLDL|*Phospholipases A2, Cytosolic|*Receptors, Estrogen|*Phospholipases A2|Hepatocytes|Orphan Nuclear Receptors|Hypertriglyceridemia|Gene Expression Regulation|Hyperlipidemias|Promoter Regions, Genetic|Mice, Inbred C57BL|Lipoproteins, LDL|Estrogens" 11 SHROOM4 30630535 BMC Med Genomics 2019 PMC6327553 10.1186/s12920-018-0471-6 0 0 0 42 Male|*Dent Disease|*Microcephaly|*Intellectual Disability|*Dwarfism|Chloride Channels|Phenotype|Mutation|Kidney 11 SLAIN2 31235723 Sci Rep 2019 PMC6591351 10.1038/s41598-019-45520-5 1 0 0 169 "Animals|*Chickens|Quantitative Trait Loci|Genome-Wide Association Study|*Body Weight|SNPs|Quantitative Trait, Heritable|Phenotype|Genomics|Module, Gene" 11 SLAIN2 30797712 EBioMedicine 2019 PMC6444028 10.1016/j.ebiom.2018.12.049 14 4 0 169 "*Colorectal Cancer|Antagomirs|RNA Interference|MicroRNAs|RNA, Long Noncoding|RNA, Small Interfering|Cell Movement|3' Untranslated Regions|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|*Neoplastic Processes|*Colon Cancer|*Microtubules" 11 SLCO5A1 31066133 Mol. 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Evol. 2019 10.1002/jez.b.22848 1 0 0 55 "Female|Male|Animals|*Zebrafish|*Transcriptome|*Ovary|Zebrafish Proteins|Gonads|Sex Differentiation|Testis|Gene Expression Regulation, Developmental|Sex Ratios|Aromatase|Gene Ontology|Reproduction|Temperature" 11 SVOPL 31093489 Int J Genomics 2019 PMC6481143 10.1155/2019/1287671 0 0 0 5 "Humans|*Alleles|Genomic Imprinting|Colorectal Cancer|Polymorphism, Single Nucleotide|Colonic Neoplasms|Chromosomes|Cell Transformation, Neoplastic" 11 TENM2 31689868 Medicine (Baltimore) 2019 PMC6946452 10.1097/MD.0000000000017821 0 1 0 25 "Humans|*Prospective Studies|*Calcium Signaling|*Tuberculosis|*Drug Induced Liver Injury|Single Nucleotide Polymorphisms|Antitubercular Agents|Genotype|Genetic Predisposition to Disease|Chinese|Alleles|Odds Ratio|Phenotypes|SLC2A13 protein, human|Glucose Transport Proteins, Facilitative" 11 TENM2 30930727 Front Neurosci 2019 PMC6428715 10.3389/fnins.2019.00109 0 0 0 25 "Animals|Evolution, Molecular|Phylogeny|Sequence Alignment|Multigene Family|Amino Acid Sequence" 11 TM2D3 31836585 Cold Spring Harb Mol Case Stud 2019 PMC6913143 10.1101/mcs.a003491 1 0 0 31 *Alleles|C9orf72 Protein|Alzheimer Disease|Genetic Association Studies|Genetic Predisposition to Disease|*Chromosome Mapping 11 VMO1 31558162 J Transl Med 2019 PMC6764142 10.1186/s12967-019-2068-z 2 0 0 4 "*Methylation|*Lung Adenocarcinoma|*Transcriptome Analysis|RNA, Long Noncoding|Prognosis|Adenocarcinoma|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Transcriptome|mRNA|Kaplan-Meier Estimate" 11 VMO1 31340078 J. Neuroendocrinol. 2019 10.1111/jne.12775 0 0 0 4 "Sheep|Female|Animals|Photoperiod|KISS1 protein, human|Kisspeptins|*Neurosecretory Systems|Hypothalamus|Pituitary Gland|Pituitary Gland, Anterior|Melatonin|Circadian Rhythm|Pineal Gland|Reproduction|Seasons|Thyrotropin|Thyroid Hormones|Iodide Peroxidase|Hypothalamus Arcuate Nucleus|Sheep, Domestic|Tanycytes" 11 VMO1 30906545 Biomed Rep 2019 PMC6423495 10.3892/br.2019.1190 1 0 0 4 "Humans|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Protein Array Analysis|*Urologic Neoplasms|Biomarkers, Tumor|Proteomics|*Gastrointestinal Cancer|*Upper Gastrointestinal Tract|*Urinary Tract|Cohort Studies|Case-Control Studies|*Urogenital System" 11 VMO1 30868060 FEBS Open Bio 2019 PMC6396159 10.1002/2211-5463.12592 2 0 0 4 "*Osteosarcoma|Bone Neoplasms|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Gene Ontology|Databases, Genetic|Protein Interaction Maps|Signal Transduction" 11 AFAP1L1 29323101 Med. Sci. Monit. 2018 PMC5772338 10.12659/msm.905900 0 19 0 36 "Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Microfilament Proteins|Short Hairpin RNA|Cell Proliferation|Apoptosis|RNA Interference|Cell Cycle|CASP3 protein, human|Caspase 3|A549 Cells|Cell Line, Tumor|Adaptor Proteins, Signal Transducing|Cell Movement|Signal Transduction|Transfection|Downregulation|Actin Cytoskeleton" 11 ANKAR 30566895 Ann. Anat. 2018 10.1016/j.aanat.2018.11.007 0 0 0 1 "Female|Pregnancy|Guinea Pigs|Animals|*Gyrus Cinguli|CALB2 protein, human|Calretinin|Parvalbumins|Calbindin-D28K|Neurons|Fetus" 11 AP3S2 30021629 Lipids Health Dis 2018 PMC6052513 10.1186/s12944-018-0806-5 0 0 0 71 "*Polymorphism, Single Nucleotide|*Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Leptin|Body Mass Index|Body Weight|Waist Circumference|Genetic Predisposition to Disease|Genotype|Triglycerides" 11 CEACAM16 30514912 J. Hum. Genet. 2018 10.1038/s10038-018-0546-4 1 0 0 3 "Humans|Nonsyndromic Deafness|*Deafness|*Mutations|Pedigree|Hearing Loss|Alleles|CEACAM6 protein, human|Antigens, CD|Cell Adhesion Molecules|GPI-Linked Proteins|ceacam16 protein, human" 11 CEACAM16 29703829 J. Med. Genet. 2018 PMC6060001 10.1136/jmedgenet-2018-105349 4 0 0 3 "*Phenotype|Hearing Loss|Deafness|Genes, Recessive|Pedigree|RNA Splice Sites|Genotype|Mutation" 11 CFAP410 29343210 J. Biomol. Struct. Dyn. 2018 10.1080/07391102.2018.1429313 0 0 0 41 "Mice|Animals|Amyotrophic Lateral Sclerosis|Mutations, Missense|Amino Acid Substitution|Molecular Dynamics Simulation|Protein Conformation|Mutations" 11 DPCR1 30278442 Cell. Physiol. Biochem. 2018 10.1159/000493966 1 0 0 11 "*Thyroid Cancer, Papillary|*Whole Exome Sequencing|Carcinoma, Papillary|Thyroid Neoplasms|*Mutation|Proto-Oncogene Proteins B-raf|Sequencing, Next-Generation|Exome|Signal Pathways" 11 DUSP18 30382394 Support Care Cancer 2018 10.1007/s00520-018-4519-0 3 0 0 121 "Humans|Quality of Life|*Leukocytes, Mononuclear|*Fatigue|Chemotherapy, Adjuvant|*Induction Chemotherapy|Antineoplastic Combined Chemotherapy Protocols|Surveys and Questionnaires|*Gene Expression|*Rare Diseases|*Mononuclear Phagocyte System|Antineoplastic Agents" 11 DUSP18 30242883 J. Cell. Biochem. 2018 10.1002/jcb.27546 1 0 0 121 "*Myocytes, Cardiac|*Whole Exome Sequencing|lncRNA|miRNAs|Transcriptome|Signal Transduction|Heart Failure|Glucose|Real-Time PCR, Quantitative|Hypertrophy" 11 DUSP18 29852174 Biochem. Biophys. Res. 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Dermatol. 2018 10.1111/exd.13729 2 0 0 143 "Humans|Mice|Dogs|Animals|AXIN2 protein, human|Axin Protein|recombinant human bone morphogenetic protein-2|Bone Morphogenetic Protein 2|Hair Follicle|BMP2 protein, human|Hair|beta Catenin|Wnt Signaling Pathway|Transforming Growth Factor beta|Cell Differentiation|Gene Expression Regulation|Morphogenesis" 11 FAM83G 29790964 Gigascience 2018 PMC6007440 10.1093/gigascience/giy058 5 2 0 143 "Swine|Animals|*Genome|Breeding|Selection, Genetic|Sus scrofa|Genotype|Chromosome Mapping|Haplotypes|*Biological Evolution|Sequence Analysis, DNA|Domestication|Phenotype|Genomics|Polymorphism, Single Nucleotide|China" 11 FAM83G 29514862 EMBO Rep. 2018 PMC5891436 10.15252/embr.201744807 8 65 0 143 "Animals|*Kinase I, Casein|Xenopus Proteins|Wnt Signaling Pathways|Axin Protein|Wnt Proteins|beta Catenin|Xenopus laevis|Intracellular Signaling Peptides and Proteins|Phosphorylation|Protein Binding" 11 FCRL6 29737217 Expert Opin. Ther. Targets 2018 10.1080/14728222.2018.1472768 5 0 0 6 "Humans|*Fc Receptor|B Cells|FCRL1 protein, human|Membrane Proteins|Immunoglobulin Isotypes|Lymphocyte Activation|Signal Transduction|Immunotherapy|Malignancies|Humans|*Fc Receptor|B Cells|FCRL1 protein, human|Membrane Proteins|Immunoglobulin Isotypes|Lymphocyte Activation|Signal Transduction|Immunotherapy|Malignancies" 11 FCRL6 30568030 JCI Insight 2018 PMC6338319 10.1172/jci.insight.120360 13 1 0 6 "Humans|*Immunotherapy|Programmed Cell Death 1 Receptor|T Cells|CTLA-4 Antigen|Lymphocyte Activation|*Immunologic Factors|Receptors, Antigen, T-Cell|Antigens, CD|Histocompatibility Antigens Class II|Cell Line, Tumor" 11 FCRL6 30076325 Exp. Mol. Med. 2018 PMC6076250 10.1038/s12276-018-0123-0 5 2 0 6 "Humans|*Depressive Disorder, Major|*Antidepressants|Serotonin Uptake Inhibitors|Mirtazapine" 11 FCRL6 29317700 Sci Rep 2018 PMC5760626 10.1038/s41598-017-18519-z 1 3 0 6 "Humans|*Kashin-Beck Disease|*Transcriptome|Leukocytes, Mononuclear|*Fluorosis, Dental|Oligonucleotide Microarray|Gene Expression Profiling|Quantitative Real Time Polymerase Chain Reaction|Downregulation|Up-Regulation|Signal Transduction|Apoptosis|Case-Control Studies" 11 FIBCD1 30279687 Front Immunol 2018 PMC6153955 10.3389/fimmu.2018.01967 3 35 0 77 11 FIBCD1 29659669 Am. J. Clin. Pathol. 2018 10.1093/ajcp/aqy013 2 0 0 77 "*Stomach Neoplasms|*Fibrinogen|Prognosis|Adenocarcinoma|Biomarkers, Tumor|Immunohistochemistry|Gene Expression Regulation, Neoplastic|Tissue Array Analysis|Real-Time Polymerase Chain Reaction|Kaplan-Meier Estimate|Lymphatic Metastasis|RNA, Messenger|Disease Progression|Blotting, Western" 11 Fibin 30327309 Clin. Cancer Res. 2018 10.1158/1078-0432.CCR-18-0777 0 0 0 13 Humans|CD8-Positive T-Lymphocytes|CD4-Positive T-Lymphocytes|Telangiectasia|Apoptosis|Fibrosis|Radiation Injuries 11 gimap7 30586737 Circulation 2018 PMC6438386 10.1161/CIRCULATIONAHA.118.034532 6 5 0 15 "*von Willebrand Factor|F8 protein, human|*Factor VIII|*Genome-Wide Association Study|*Blood Coagulation Tests|Venous Thrombosis|Blood Coagulation|*Plasma|Case-Control Studies|Polymorphism, Single Nucleotide|Phenotype|Risk Factors" 11 HHATL 30184078 FEMS Yeast Res. 2018 10.1093/femsyr/foy097 0 4 0 15 "*Saccharomyces cerevisiae|VDAC1 protein, human|*Voltage-Dependent Anion Channel 1|Saccharomyces cerevisiae Proteins|*Mitochondria|*Acyltransferases|*Programmed Cell Death|Intracellular Membranes|Membrane Transport Proteins|Porins|*Cell Wall|Acetic Acid|Por1 protein, S cerevisiae" 11 IGSF9B 30573727 Nat Commun 2018 PMC6302093 10.1038/s41467-018-07762-1 0 0 0 45 11 IGSF9B 30217166 J Neuroinflammation 2018 PMC6138928 10.1186/s12974-018-1307-1 4 0 0 45 "Humans|*Multiple Sclerosis|*Exome|*Whole Exome Sequencing|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|*Disease Progression|Genotype" 11 IQCG 30168948 Zhonghua Nan Ke Xue 2018 0 0 0 22 "Male|Humans|*Testis|*Asthenozoospermia|Sperm Motility|Sperm|RNA, Messenger|Case-Control Studies" 11 IQCG 30109096 R Soc Open Sci 2018 PMC6083711 10.1098/rsos.180413 7 0 0 22 "Male|Cattle|Animals|*RNA, Circular|*Testis|RNA, Micro|Gene Expression Profiling|Gene Ontology|Downregulation|Upregulation|Spermatogenesis|Signal Transduction" 11 IQCG 30081822 Genet. Sel. Evol. 2018 PMC6080523 10.1186/s12711-018-0412-z 5 2 0 22 Swine|Animals|*Genome-Wide Association Study|*Semen|*Gene Regulatory Networks|Quantitative Trait Loci|*Phenotypes|Genotypes|Sus scrofa|Single Nucleotide Polymorphisms 11 KLHL14 30086079 Spine 2018 10.1097/BRS.0000000000002827 2 0 0 34 "Mice|Animals|*RNA, Anti-Sense|*Intervertebral Disk|Notochord|Paired Box Transcription Factors|Gene Expression Regulation, Developmental|PAX9 Transcription Factor|In Situ Hybridization|Organogenesis" 11 KLHL14 29939266 Int. Immunol. 2018 10.1093/intimm/dxy033 3 1 0 34 "Mice|Animals|Cells, B-1|Immunoglobulin M|B Cells|*Lymphocyte Activation|Spleen|*Proteins|Mice, Inbred C57BL|Peritoneal Cavity|Adoptive Transfer|*Hematopoiesis|Liver|Peritoneum" 11 LRP11 30008265 Mol. 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Feline Med. Surg. 2018 10.1177/1098612X18816460 0 0 0 25 "Cats|Animals|*Precision Medicine|Cardiomyopathy, Hypertrophic|Genetic Predisposition to Disease|Genotype|Carrier Proteins|Mutation|Echocardiography" 11 MFSD12 30408154 Am. J. Phys. Anthropol. 2018 10.1002/ajpa.23737 2 0 0 25 "Humans|Skin Color|Receptor, Melanocortin, Type 1|Eye Color|Agouti Signaling Protein|Hair Color|Phenotype|*Skin|Genotype|Membrane Transport Proteins|Antiporters|Polymorphism, Single Nucleotide|European Continental Ancestry Group|Membrane Glycoproteins|Antigens, Neoplasm" 11 MFSD12 30385854 Oncogene 2018 PMC6462865 10.1038/s41388-018-0531-6 4 4 0 25 "Humans|*Computational Biology|Phosphatidylinositol 3-Kinases|*Melanoma|Skin Neoplasms|*Cell Proliferation|Prognosis|Gene Expression Regulation, Neoplastic|Upregulation|Disease Progression|Cell Movement|Gene Expression Profiling|Biomarkers, Tumor|Disease-Free Survival|Signal Transduction|Cell Line, Tumor|Genes, cdc" 11 MFSD12 30252177 Mol. 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J. Obstet. Gynecol. Reprod. Biol. 2017 10.1016/j.ejogrb.2017.08.036 1 0 0 34 Humans|Female|*Hyperplasia|*Endometrial Cancer|Endometrial Hyperplasia|DNA Methylation 11 LYZL4 28182716 PLoS ONE 2017 PMC5300149 10.1371/journal.pone.0171452 0 2 0 5 "Male|Cricetinae|Humans|Mice|Animals|*Sperm|Epididymis|Testis|lysozyme C, human|Lysozyme|Genitalia, Male|Amino Acid Sequence|*Bacteriolysis|Blotting, Western|Spermatozoa Maturation|LYZL4 protein, human|LYZL6 protein, human" 11 LYZL4 29658230 Zhonghua Nan Ke Xue 2017 0 1 0 5 "Male|Humans|*Testis|*Antibodies|Blotting, Western|Spermatozoa|Enzyme-Linked Immunosorbent Assay|Antibody Specificity|Lysozyme|Escherichia coli|LYZL4 protein, human" 11 MAATS1 28592604 Am. J. Clin. 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Cell Proteomics 2017 PMC5795394 10.1074/mcp.RA117.000315 9 4 0 11 "Mice|Animals|*Plaque, Atherosclerotic|*Osteoclasts|*Proteomics|*Atherosclerosis|*Aorta|Mice, ApoE Knockout|Apolipoproteins E|Macrophages|peroxidasin|Extracellular Matrix Proteins|Mice, Inbred C57BL|Proteome|Apoptosis|Extracellular Matrix|Peroxidase" 11 MAMDC2 29030909 Cancer Med 2017 PMC5727298 10.1002/cam4.1187 11 4 0 11 "Humans|*Imatinib Mesylate|*Transcriptome|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Fusion Proteins, bcr-abl|Hematopoietic Stem Cells|Pyrimidines|Benzamides|Piperazines|Neoplastic Stem Cells|Protein Kinase Inhibitors|Apoptosis|Hematopoietic Stem Cell Transplantation" 11 MAMDC2 28386848 Mol. Neurobiol. 2017 10.1007/s12035-017-0483-9 2 0 0 11 "Humans|*Spasms, Infantile|*Whole Exome Sequencing|Autism Spectrum Disorder|Exome|Mutations|Epilepsy|Genetic Predisposition to Disease|Intellectual Disability|Amino Acid Sequence|Chinese|Bioinformatic|Networks, Gene" 11 MFSD12 29025994 Science 2017 PMC5759959 10.1126/science.aan8433 48 8 0 25 "Humans|*Skin Pigmentation|Gene Frequency|Haplotypes|European Continental Ancestry Group|Asian Continental Ancestry Group|Genetics, Population|Alleles|Selection, Genetic|African Continental Ancestry Group|Ethnic Groups|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genotype|Biological Evolution|Antiporters" 11 NBEAL1 29218114 Am J Transl Res 2017 PMC5714800 7 0 0 21 "Humans|*RNA, Circular|Esophageal Neoplasms|Esophageal Squamous Cell Carcinoma|*Transcriptome|miRNA|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Bioinformatics|Real-Time Polymerase Chain Reaction|*Cell Lines" 11 NBEAL1 28642624 Sci Rep 2017 PMC5481334 10.1038/s41598-017-04433-x 4 5 0 21 "Humans|Adolescent|*Whole Exome Sequencing|Studies, GWA|*Atherosclerosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Exome|Coronary Artery Disease|Alleles|European Continental Ancestry Group|Genetic Variation|Myocardial Infarction|Case-Control Studies|Phenotype|Risk Factors" 11 OTOGL 28742274 Am. 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Thromb. Haemost. 2017 10.1111/jth.13861 7 0 0 169 "Humans|*Receptor, Retinoic Acid|*Blood Platelets|Tretinoin|Retinoic Acid Receptor alpha|mRNA|Signal Transduction|SLAIN2 protein, human|Microtubule-Associated Proteins" 11 SLAIN2 28600779 Hum. Genet. 2017 PMC5502059 10.1007/s00439-017-1821-8 39 1 0 169 "Humans|*Exome|Saudi Arabia|Nerve Tissue Proteins|Endoplasmic Reticulum|Golgi Apparatus|Receptors, Immunologic|Vesicular Transport Proteins|Sequencing, Whole Exome|Genes, Recessive|Homozygote|Mutations|Sequencing, Next-Generation|Sequence Analysis, DNA|Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|GRSF1 protein, human" 11 SLCO5A1 29183809 Mol. Cell. Endocrinol. 2017 10.1016/j.mce.2017.11.019 9 1 0 47 "Humans|*DNA Methylation|Diabetes Mellitus, Type 2|*Pancreatic Islets|Insulin Secretion|*Gene Expression|Insulin-Secreting Cells|Insulin|Epigenesis, Genetic|Hyperglycemia|Glucose|Promoter Regions, Genetic|RNA, Messenger|*Biochemical Phenomena" 11 SLCO5A1 28328141 Am. J. Med. Genet. A 2017 10.1002/ajmg.a.38122 1 0 0 47 "Humans|Female|Child|Mesomelia-synostoses syndrome|*Long Interspersed Nucleotide Elements|*Synostoses|*Limb Deformities, Congenital|*Abnormalities, Multiple|*Alleles|*Homologous Recombination|Sequence Deletion" 11 SPATA19 28972294 APMIS 2017 10.1111/apm.12775 0 0 0 10 "Humans|Male|*Prostatic Hyperplasia|*Testis|*Prostate Cancer|Prostate|Antigens, Neoplasm|Biomarkers, Tumor|IL13RA1 protein, human|*Interleukin-13 Receptor alpha1 Subunit|*Spermatogenesis|Proteomics|Cohort Studies|SPATA19 protein, human|Mitochondrial Proteins|Seminal Plasma Proteins" 11 SPATA19 28867149 Neurobiol. 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Med. 2017 10.1038/gim.2017.111 11 0 0 5 "Humans|Female|Pregnancy|*Autopsy|Whole Exome Sequencing|Exome|Phenotypes|Sequence Analysis, DNA|Mutation|Chromosome Mapping|Genetic Predisposition to Disease|DNA|Fetus|Cohort Studies|KRIT1 protein, human|KRIT1 Protein|FCRL4 protein, human|Receptors, Fc|WDR81 protein, human|Nerve Tissue Proteins" 11 TENM2 28106375 ACS Chem. Biol. 2017 10.1021/acschembio.6b01154 9 1 0 25 "Humans|*Klebsiella pneumoniae|Escherichia coli|*Acinetobacter|Acinetobacter gyllenbergii|microcin|Bacteriocins|*RNA Polymerase|*Peptides|Anti-Bacterial Agents|Amino Acid Sequence|Protein Conformation|Receptors, Cell Surface|FhuA protein, E coli|Bacterial Outer Membrane Proteins|Escherichia coli Proteins" 11 TENM2 28088466 Mol. Cell. Endocrinol. 2017 10.1016/j.mce.2017.01.015 7 2 0 25 "Humans|Mice|Animals|Brown Adipocyte|Adipocytes, White|*Cell Differentiation|Uncoupling Protein 1|Adipogenesis|Mitochondria|Mitochondrial Proteins|Adipose Tissue, White|Cell Transdifferentiation|Progenitor Cells|Adipose Tissue, Subcutaneous|Cells, Cultured|mRNA|Ucp1 protein, mouse" 11 TM2D3 29223476 Reprod. Biomed. Online 2017 10.1016/j.rbmo.2017.10.115 1 0 0 31 "Infant|Humans|Infant, Newborn|Female|Male|Comparative Genomic Hybridization|Ring Chromosomes|Karyotyping|Insulin-Like Growth Factor I, Resistance To|Abnormalities, Multiple|*Subfertility|In Situ Hybridization, Fluorescence|Mosaicism|*Fecundity|Phenotype|Growth Disorders|Intellectual Disability|Haploinsufficiency|Gene Dosage|PCSK6 protein, human|Serine Endopeptidases|Proprotein Convertases" 11 UFSP2 28892125 Clin. Genet. 2017 10.1111/cge.13134 4 0 0 51 "Humans|Hip Dysplasia, Beukes Type|*Osteochondrodysplasias|Pyle disease|*Mutation|Genetic Association Studies|Pedigree|Hip Dislocation, Congenital|Phenotype|Epiphyses|Whole Exome Sequencing|Hip Joint|Radiography|UFM1 protein, human|Proteins" 11 36951 27830771 Sci Rep 2016 PMC5103264 10.1038/srep36951 4 0 1 0 *Silicon|*Temperature|*Nanocrystals|Particle Size|Surface Properties|Quantum Dots|*Alkanes 11 AFAP1L1 27349187 Acta Trop. 2016 10.1016/j.actatropica.2016.06.028 2 1 0 36 "Animals|*Trypanosoma cruzi|Chagas Disease|*Filaments, Actin|*Cytoplasm|Actins|Actin Binding Proteins" 11 AFAP1L1 26998266 Biomed Rep 2016 PMC4774376 10.3892/br.2016.588 2 0 0 36 "Humans|Phosphatidylinositol 3-Kinases|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|*Adaptor Proteins, Signal Transducing|*Signal Transduction|Cell Proliferation|Cell Cycle|Proto-Oncogene Proteins c-akt|Microfilament Proteins|Cell Line, Tumor|Protein-Tyrosine Kinases|RNA, Small Interfering|mRNA|AFAP1L1 protein, human" 11 ANKAR 27771351 J. Chem. Neuroanat. 2016 10.1016/j.jchemneu.2016.10.001 0 0 0 1 "Guinea Pigs|Animals|*Calbindin|CALB2 protein, human|*Calbindin 2|*Parvalbumins|*Calcium-Binding Proteins|*Neurons|Immunohistochemistry" 11 AP3S2 27391584 Genet Test Mol Biomarkers 2016 10.1089/gtmb.2016.0062 4 1 0 71 "Humans|*Carcinoma, Hepatocellular|*Hepatitis B, Chronic|*Liver Neoplasms|*Risk Factors|Hepatitis B virus|Liver Cirrhosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Complement Factor B|Haplotypes|Gene Frequency|Case-Control Studies" 11 CFAP410 27548899 Invest. Ophthalmol. Vis. Sci. 2016 10.1167/iovs.16-19450 3 0 0 41 "Humans|*Cone-Rod Dystrophies|Japan|*Retinitis Pigmentosa|Genes, Recessive|Electroretinography|Retinal Rod Photoreceptor Cells|Pedigree|Exome|Mutation, Missense|Phenotype|C21orf2 protein, human" 11 CFAP410 27455348 Nat. Genet. 2016 PMC5556360 10.1038/ng.3622 92 1 0 41 "Humans|*Genome-Wide Association Study|*Amyotrophic Lateral Sclerosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|Case-Control Studies|Phenotype|C21orf2 protein, human" 11 CFAP410 26974433 PLoS ONE 2016 PMC4790905 10.1371/journal.pone.0150555 5 0 1 41 "Humans|Strudwick syndrome|Spondylometaphyseal dysplasia, axial|*Osteochondrodysplasias|Pyle disease|*Mutations|Jeune syndrome|Ellis-Van Creveld Syndrome|Genes, Recessive|Homozygote|Retinal Dystrophy|Pedigree|Cytoskeletal Proteins|Phenotypes|Retina|C21orf2 protein, human" 11 dchs2 26876984 Int J Geriatr Psychiatry 2016 10.1002/gps.4440 0 0 0 7 "*Alzheimer Disease|Genome-Wide Association Study|*Cognitive Impairment, Mild|Apolipoprotein E4|Apolipoproteins E|Neuropsychological Tests|Genotype|Alleles|Brazil" 11 dchs2 27193062 Nat Commun 2016 PMC4874031 10.1038/ncomms11616 36 5 3 7 "Humans|Mice|Animals|*Genome-Wide Association Study|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|*Face|Phenotypes|Single Nucleotide Polymorphisms|Edar Receptor|Genotype|Asian Continental Ancestry Group|European Continental Ancestry Group|GLI3 protein, human|Zinc Finger Protein Gli3|Nerve Tissue Proteins|EDAR protein, human|Edar protein, mouse|Gli3 protein, mouse|Runx2 protein, mouse" 11 DPCR1 27698795 Oncol Lett 2016 PMC5038494 10.3892/ol.2016.5029 8 3 1 11 "*Pituitary Neoplasms|*Whole Exome Sequencing|Neoplasm Recurrence, Local|Adenoma|PRDM2 protein, human|DNA-Binding Proteins|Transcription Factors|Nuclear Proteins|Histone-Lysine N-Methyltransferase|Exomes|F-actin-binding proteins|Carrier Proteins|Gene Expression Regulation, Neoplastic|Microfilament Proteins|Cell Transformation, Neoplastic" 11 DPRX 27578796 Development 2016 PMC5087614 10.1242/dev.134510 5 5 1 4 "Humans|*Genes, Homeobox|Preimplantation Embryos|Homeodomain Proteins|*Embryo, Mammalian|Embryonic Development|Transcription Factor|*Genome|Gene Expression Regulation, Developmental|Embryonic Stem Cells|Human Embryonic Stem Cell|Transcriptional Activation|LEUTX protein, human" 11 DPRX 27412763 Sci Rep 2016 PMC4944136 10.1038/srep28995 11 14 1 4 "Pregnancy|Female|Humans|*Genes, Homeobox|Proteins, Homeo Domain|Transcription Factors|Preimplantation Embryos|Gene Expression Regulation, Developmental|Preimplantation Embryo Development|Amino Acid Sequence|Fetal Proteins|Embryo, Mammalian" 11 DPRX 27296695 BMC Biol. 2016 PMC4904359 10.1186/s12915-016-0267-0 9 0 1 4 "Animals|*Genes, Homeobox|*Mammals, Eutherian|*Genetic Evolution|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Genome" 11 DPRX 27165889 Acta Neurochir. Suppl. 2016 10.1007/978-3-319-22533-3_23 1 0 0 4 Humans|*Intracranial Hypertension|Intracranial Pressure|*Traumatic Brain Injury|Glasgow Outcome Scale|Cerebrovascular Circulation|Retrospective Studies|Prognosis 11 EFR3A 27867060 Neuroscience 2016 10.1016/j.neuroscience.2016.11.013 2 0 0 48 "Mice|Animals|Spiral Ganglion|*Presbycusis|Hair Cells, Auditory|Hearing|Cochlea|Evoked Potentials, Auditory, Brain Stem|Mice, Inbred C57BL|Nerve Degeneration|Neurons|Disease Models, Animal|EFR3A protein, mouse|Membrane Proteins" 11 EFR3A 27303058 Sci Signal 2016 10.1126/scisignal.aaf3572 17 0 0 48 "Animals|*Focal Adhesions|*Biotinylation|PXN protein, human|Paxillin|Membrane Proteins|Cytoskeletal Proteins|Cell Adhesion|Adaptor Proteins, Signal Transducing|Neoplasm Proteins|Integrins|Protein Binding|Binding Protein|Cells, Cultured|Extracellular Matrix" 11 FAM136A 27083884 J. Neurol. 2016 PMC4833787 10.1007/s00415-015-7988-9 14 0 2 96 "Humans|Deafness, Autosomal Dominant 15|Hearing Loss, Sensorineural|*Vestibular Diseases|Deafness, Autosomal Dominant 11|Deafness, Autosomal Dominant 9|Meniere Disease|Deafness, Autosomal Dominant 28|Vertigo|Pedigree|Mutation" 11 FAM83G 27784791 Open Biol 2016 PMC5090066 10.1098/rsob.160255 16 21 1 143 "Animals|Humans|*Proteolysis|HEK293 Cells|Von Hippel-Lindau Tumor Suppressor Protein|Ubiquitylation|Proteasome|Cell Line, Tumor" 11 FAM83G 26747202 G3 (Bethesda) 2016 PMC4777115 10.1534/g3.115.025643 6 0 1 143 "Dogs|Animals|Genome-Wide Association Study|*Sequencing, Whole Genome|Genomics|High-Throughput Nucleotide Sequencing|Chromosome Mapping|Polymorphism, Single Nucleotide|Genotype|INDEL Mutation|Dog Diseases|Phenotype|Alleles" 11 Fibin 26913079 Mol Cytogenet 2016 PMC4765068 10.1186/s13039-016-0227-y 9 1 1 13 *Wilms Tumor|*Oncogenes|*Genomics|DNA Copy Number Variations|Comparative Genomic Hybridization|Loss of Heterozygosity|Chromosome Aberrations|Kidney Neoplasms 11 HHATL 29615596 J Dev Biol 2016 PMC5831804 10.3390/jdb4040033 0 48 0 15 "Animals|*Saccharomyces cerevisiae|*Hedgehogs|*Yeast, Dried|Lipoylation|Hedgehog Proteins|*Morphogenesis|Acyltransferases|FACT protein, S cerevisiae|DNA-Binding Proteins|High Mobility Group Proteins|Saccharomyces cerevisiae Proteins|Transcriptional Elongation Factors" 11 HHATL 27697108 BMB Rep 2016 PMC5346324 10.5483/bmbrep.2016.49.11.151 0 2 0 15 "Humans|Male|Animals|Mice|*Protein Domains|Endoplasmic Reticulum|Membrane Proteins|Amino Acid Sequence|In Situ Hybridization|Sequence Homology, Amino Acid|Gene Expression Regulation, Developmental|Blotting, Western|Immunoprecipitation" 11 IGSF9B 27080536 Chromosoma 2016 10.1007/s00412-016-0589-2 6 0 0 45 "Animals|*Synteny|In Situ Hybridization, Fluorescence|Phylogeny|*Sex Chromosome|*Gene Mapping|*Flatfishes|Bacterial Artificial Chromosome|Karyotyping|Evolution, Molecular|Genomics|Oryzias latipes|Sex Determination Analysis|Bioinformatics" 11 IQCG 27864780 Front Med 2016 10.1007/s11684-016-0489-0 0 2 0 22 "Humans|Mice|Animals|*Active Transport, Cell Nucleus|nuclear pore complex protein 98|Nuclear Pore Complex Proteins|Karyopherins|*Leukemia|Receptors, Cytoplasmic and Nuclear|Cell Nucleus|Homeodomain Proteins|Translocation, Genetic|*Carcinogenesis|HeLa Cells" 11 LYZL4 27832206 PLoS ONE 2016 PMC5104373 10.1371/journal.pone.0166321 0 2 0 5 "Male|Animals|hen egg lysozyme|lysozyme C, human|*Muramidase|*Phylogeny|Chromatography, Liquid|Tandem Mass Spectrometry|*Sperm|Amino Acid Sequence|Testis|Seminal Plasma Proteins|Cloning, Molecular|cDNA" 11 LYZL4 27821286 J. 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Immunol. 2016 10.1016/j.jri.2016.11.001 0 0 0 5 Male|Rats|Animals|*Muramidase|*Sperm|Acrosome Reaction|*Fertility|Epididymis|*Immunizations|Sperm Capacitation|Sperm-Ovum Interactions|Testis|*Vaccination|Amino Acid Sequence|Reproduction 11 LYZL4 27611690 PLoS ONE 2016 PMC5017655 10.1371/journal.pone.0161909 1 2 1 5 "Male|Rats|Animals|*Muramidase|Epididymis|Testis|Spermatozoa|Amino Acid Sequence|Genitalia, Male|*In Silico" 11 MAATS1 27855487 Hum Gene Ther Clin Dev 2016 PMC5310237 10.1089/humc.2016.119 3 0 0 14 "Humans|Animals|Infant, Newborn|*Macaca mulatta|Disease, Pompe's|Adeno-Associated Virus|alpha-Glucosidases|Genetic Vectors|Genetic Therapy|Glycogen|Muscle, Skeletal|Myocardium|Disease Models, Animal" 11 MAMDC2 27785066 Onco Targets Ther 2016 PMC5067006 10.2147/OTT.S113855 7 0 1 11 "Humans|Female|*Gene Expression Profiling|Carcinoma, Ductal, Breast|Carcinoma, Intraductal, Noninfiltrating|Prognosis|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Breast Neoplasms" 11 MAMDC2 27605433 Sci Rep 2016 PMC5015102 10.1038/srep32643 27 5 1 11 "Humans|*Exosomes|Proteomics|Endothelial Cells|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|*Oncogenesis|*Oncogenes|Tumor Microenvironment|Cell Communication|Signal Transduction|Cell Line, Tumor|Neovascularization, Pathologic|Cell Movement|*Biological Transport|Disease Progression" 11 MAMDC2 27431290 Mol. Psychiatry 2016 10.1038/mp.2016.113 40 0 0 11 "Humans|*Intellectual Disability|Exome|Genes, Recessive|Whole Exome Sequencing|Mutations|Homozygote|Genes, X-Linked|DNA Copy Number Variations|Sequence Analysis, DNA|Phenotypes|Genomics|Cohort Study|UBE4A protein, human|Ubiquitin-Protein Ligases|NUDT2 protein, human|Phosphoric Monoester Hydrolases" 11 MTG2 27346661 Sci Rep 2016 PMC4921815 10.1038/srep28673 0 0 1 47 "*Botrytis|*Virulence|Gene Expression Regulation, Fungal|Fungal Proteins|Spores, Fungal|Genes, Fungal|Osmotic Stress|Saccharomyces cerevisiae|Stress, Physiological|Genetic Complementation Test|Plant Diseases|Stresses, Oxidative|Osmosis|Cell Wall|Gene Deletion" 11 MTG2 26755623 Bioinformatics 2016 PMC4848406 10.1093/bioinformatics/btw012 36 0 1 47 "Humans|Mice|Animals|*Multivariate Analysis|*Genomics|*Model, Linear|*Algorithm|*Genome|Software|Genome-Wide Association Study|SNPs|Phenotype" 11 NBEAL1 27184124 Mol. Psychiatry 2016 PMC5114162 10.1038/mp.2016.71 7 3 0 21 Humans|*Body Mass Index|Genome-Wide Association Study|*Anorexia Nervosa|*Genetic Loci|Single Nucleotide Polymorphisms|Body Weight|Obesity|Genetic Predisposition to Disease|Linkage Disequilibrium|Alleles|Underweight|Phenotype|Genetic Variation 11 OTOGL 27340278 Clin. Cancer Res. 2016 PMC5182193 10.1158/1078-0432.CCR-16-0720 13 4 0 2 "*Carcinoma, Mucoepidermoid|*Whole Exome Sequencing|*Salivary Gland Neoplasms|DNA-Binding Proteins|Transcription Factors|Oncogene Proteins, Fusion|Nuclear Proteins|Translocation, Genetic|In Situ Hybridization, Fluorescence|Salivary Glands" 11 PDZD8 27775175 J. Neurosci. Res. 2016 10.1002/jnr.23957 3 0 0 166 "Humans|*Stress Disorders, Post-Traumatic|Genome-Wide Association Study|Genetic Predisposition to Disease|Allele|Polymorphism, Single Nucleotide|Quantitative Trait Loci|*Brain|Genotype|*Risk Factors|Whole Exome Sequencing|Amygdala|Gene Expression" 11 PLA2G12B 27471003 Mol. Cell. Endocrinol. 2016 10.1016/j.mce.2016.07.027 2 6 0 8 "Mice|Animals|nuclear receptor subfamily 0, group B, member 2|Receptors, Cytoplasmic and Nuclear|very low density lipoprotein triglyceride|*Triglycerides|Chenodeoxycholic Acid|Very-Low-Density Lipoproteins|Bile Acids|DNA-Binding Proteins|*Phospholipases A2, Cytosolic|*Phospholipases A2|Liver|Hepatocyte Nuclear Factor 4-alpha|GW 4064|Isoxazoles|Promoter Regions, Genetic|Up-Regulation|HepG2 Cells" 11 SFSWAP 27376950 Front Med 2016 10.1007/s11684-016-0454-y 5 0 0 225 "Animals|Mice|*Alternative Splicing|Chickens|*Ear, Inner|Hair Cells, Auditory, Inner|Cochlea|Exon|Large-Conductance Calcium-Activated Potassium Channels|Large-Conductance Calcium-Activated Potassium Channel alpha Subunits|*Gene Expression|Hearing Loss|Deafness|Genetic Variation|Vertebrates|Cdh23 protein, mouse|Cadherins" 11 SHROOM4 26740508 J. Med. Genet. 2016 10.1136/jmedgenet-2015-103568 36 0 1 42 "*Rett Syndrome|*Phenotypes|Methyl-CpG-Binding Protein 2|Sequencing, Whole Exome|Exome|High-Throughput Nucleotide Sequencing|Mutation|Nerve Tissue Proteins|Array Comparative Genomic Hybridization|Forkhead Transcription Factors" 11 SLAIN2 27939686 Dev. Cell 2016 PMC5178967 10.1016/j.devcel.2016.11.009 17 23 0 169 Mice|Animals|*Microtubule|Microtubule-Associated Proteins|Tubulin|Cell Migration|Protein Binding|Protein Transport|Signal Transduction|*B-Lymphocytes 11 SLCO5A1 27764917 Asian-australas. J. Anim. Sci. 2016 PMC5411823 10.5713/ajas.16.0637 4 13 0 47 "Pregnancy|Female|Swine|Animals|multidrug resistance-associated protein 1|*Estrous Cycle|*Endometrium|Multidrug Resistance-Associated Proteins|*Uterus|Pregnancy, Animal|*Organic Anion Transporters|*Membrane Transport Proteins|Embryo, Mammalian|RNA, Messenger|Prostaglandins" 11 SLCO5A1 26949921 Int. J. Cancer 2016 PMC5579720 10.1002/ijc.30081 15 0 0 47 "Humans|*Human Papilloma Virus|*Papillomavirus Infections|*Squamous Cell Carcinoma of Head and Neck|Neoplasm Recurrence, Local|*Oropharyngeal Neoplasms|Carcinoma, Squamous Cell|*Mouth Neoplasms|Biomarkers, Tumor|*Gene Fusions|Whole Exome Sequencing|Head and Neck Neoplasms" 11 SPATA17 27802063 Syst Biol Reprod Med 2016 10.1080/19396368.2016.1243741 2 0 0 6 "Humans|Male|*Streptococcus agalactiae|*Infertility, Male|Antigens, Bacterial|Epitopes, T-Lymphocyte|Epitope Mapping|Amino Acid Sequence|Bacterial Proteins|Semen" 11 SVOPL 27862604 Hum. Mutat. 2016 PMC5225243 10.1002/humu.23146 19 0 0 5 "Male|*Translocation, Genetic|*Sequencing, Whole Genome|*Cytogenetic|Chromosome Breakage|Phenotypes|Chromosome Mapping|Sequence Analysis, DNA|In Situ Hybridization, Fluorescence|Homologous Recombination|DNA End-Joining Repair|Chromosomes" 11 SVOPL 26819647 Clin Epigenetics 2016 PMC4728790 10.1186/s13148-016-0175-8 9 11 1 5 "Humans|*DNA Methylation|*B-DNA|*Pseudohypoparathyroidism|Chromogranins|GTP-Binding Protein alpha Subunits, Gs|Genomic Imprinting|Epigenesis, Genetic|*Protein Processing, Post-Translational|GNAS protein, human" 11 TM2D3 27893753 PLoS Genet. 2016 PMC5125558 10.1371/journal.pgen.1006456 0 0 0 31 *Alzheimer Disease 11 TM2D3 27764101 PLoS Genet. 2016 PMC5072721 10.1371/journal.pgen.1006327 17 3 1 31 Animals|Humans|*Alzheimer Disease|Presenilin-1|Amyloid beta-Protein Precursor|Apolipoproteins E|Phenotype|Allele|Mutation|Exome|Drosophila|Signal Transduction|Iceland 11 TM2D3 27160288 Cytogenet. Genome Res. 2016 10.1159/000445923 0 0 0 31 "Humans|Male|Prader-Willi Syndrome|Chromosome Banding|Translocation, Genetic|Chromosome Deletion|Karyotyping|In Situ Hybridization, Fluorescence|Phenotype|DNA Methylation|*Chromosome Structures|Metaphase|Chromosome 15" 11 UFSP2 27926783 FEBS Lett. 2016 10.1002/1873-3468.12518 6 1 0 51 Proteins|Ubiquitin-Activating Enzymes|Endoplasmic Reticulum|Ubiquitin-Conjugating Enzymes|Ubiquitins 11 UFSP2 27240952 Biochem. Biophys. Res. Commun. 2016 10.1016/j.bbrc.2016.05.143 0 0 0 51 "Animals|*Caenorhabditis elegans|Caenorhabditis elegans Proteins|Amino Acid Sequence|Crystallography, X-Ray|endopeptidase B|Cysteine Endopeptidases|Binding Sites|Sequence Alignment|Endoplasmic Reticulum" 11 AFAP1L1 26212012 Oncogene 2015 10.1038/onc.2015.272 0 7 0 36 "*Phosphotyrosine|*Podosomes|Phosphatidylinositol 3-Kinases|*Cell Migration|*Sarcoma|Actins|Cortactin|SH2 Domains|Cytoskeleton|Adaptor Proteins, Signal Transducing|Phosphorylation|Attenuated familial adenomatous polyposis|*Adenomatous Polyposis Coli|src-Family Kinases|Actin Cytoskeleton|Protein Binding|*Soft Tissue Neoplasms|Cell Line, Tumor" 11 ANKAR 26617160 Ann. Anat. 2015 10.1016/j.aanat.2015.10.005 0 0 0 1 "Animals|Guinea Pigs|*Calcium-Binding Proteins|cocaine- and amphetamine-regulated transcript protein|CALB2 protein, human|Calretinin|Calbindin|Nerve Tissue Proteins|Parvalbumins|Neurons|Subiculum|Immunofluorescence|*Brain" 11 AP3S2 26395551 Eur. J. Hum. Genet. 2015 PMC4867451 10.1038/ejhg.2015.212 11 0 3 71 "Humans|*Diabetes Mellitus, Type 2|Pakistan|*Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|SNPs|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Genotype|*Ethnic Groups|Alleles|Case-Control Studies|FTO protein, human" 11 CDH20 26081465 Dev. Growth Differ. 2015 PMC4744772 10.1111/dgd.12228 4 1 0 17 "Female|Pregnancy|Animals|Mice|*Callithrix|*Cerebral Cortex|osteoblast cadherin|*Cadherins|H-cadherin|CDH10 protein, human|Neurogenesis|Gene Expression Regulation, Developmental|Brain" 11 CEACAM16 26691158 J. Assoc. Res. Otolaryngol. 2015 PMC4791414 10.1007/s10162-015-0551-7 6 0 0 3 "Humans|Mice|Animals|*Tectorial Membrane|*Otoacoustic Emissions, Spontaneous|Auditory Threshold|Acoustic Stimulation|Hearing Loss, Sensorineural|Extracellular Matrix Proteins|GPI-Linked Proteins|Mutations|Disease Models, Animal|ceacam16 protein, human|Cell Adhesion Molecules|OTOA protein, human|Otoa protein, mouse" 11 CEACAM16 26648831 Mol Syndromol 2015 PMC4662267 10.1159/000439576 2 0 0 3 "Humans|Child|*Hearing Impairment|Nonsyndromic Deafness|Deafness|Pedigree|Hearing Loss, Sensorineural|Genes, Dominant|Mutation|Mutations, Missense|Asian Continental Ancestry Group|ceacam16 protein, human|Cell Adhesion Molecules" 11 CEACAM16 25589040 J. Hum. Genet. 2015 PMC4375019 10.1038/jhg.2014.114 6 0 2 3 "Humans|Nonsyndromic Deafness|*Exome|HEK293 Cells|*Deafness|*Whole Exome Sequencing|Deafness, Autosomal Dominant 4|Hearing Loss, Sensorineural|*Chinese|Pedigree|Genes, Dominant|Sequencing, Next-Generation|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Mutation|Genetic Linkage|Missense Mutation|Sequence Analysis, DNA|Phenotype" 11 CFAP410 26294103 Br J Ophthalmol 2015 10.1136/bjophthalmol-2015-307277 2 0 1 41 "*Cilia|*Retinal Dystrophy|Genes, Recessive|Electroretinography|Retina|DNA Mutational Analysis|Pedigree|Mutation|Phenotype|Proteins|Tomography, Optical Coherence|Mutation, Missense" 11 CFAP410 26290490 Acta Biochim. Biophys. Sin. 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Cancer Res. 2015 10.1158/1078-0432.CCR-14-2188 10 0 2 323 "*Minor Histocompatibility Antigens|Hematopoietic Stem Cell Transplantation|T-Lymphocytes|Graft vs Host Disease|*B-Lymphocytes|Transplantation, Homologous|Graft vs Leukemia Effect|*HLA-B|*Lymphocyte|HLA-A2 Antigen|Epitopes, T-Lymphocyte" 11 CLYBL 25587899 PLoS ONE 2015 PMC4294658 10.1371/journal.pone.0116032 14 7 1 323 Humans|*Human Induced Pluripotent Stem Cells|*Transcription Activator-Like Effector Nucleases|*Transcription Activator-Like Effectors|*Transgene|*Endonucleases|Reporter Gene|Cell Lines|Genetic Vectors|Gene Targeting|Transfection|*Neural Stem Cell|Cell Differentiation|Zinc Fingers|Genetic Engineering|Green Fluorescent Proteins|Gene Expression 11 dchs2 26160902 Development 2015 PMC4529026 10.1242/dev.119800 3 2 0 7 "Humans|Animals|*Zebrafish|*Actins|*Cytoskeleton|*Embryogenesis|Zebrafish Proteins|*Cadherins|Microtubules|Embryo, Nonmammalian|Actin Cytoskeleton|Gastrulation|Cytoskeletal Proteins|Cytoplasm|Signal Transduction|Cell Adhesion|DCHS1 protein, human|DCHS1b protein, zebrafish" 11 dchs2 26116661 Development 2015 10.1242/dev.122648 23 1 4 7 "Mice|Animals|*Nephron|Cell Differentiation|Signal Transduction|Transcription Factors|Cadherins|Kidney|Phosphoproteins|Stem Cells|Adaptor Proteins, Signal Transducing|Mesenchyme|Mice, Knockout|Dchs1 protein, mouse|Fat4 protein, mouse" 11 DPCR1 25884948 BMC Cancer 2015 PMC4407330 10.1186/s12885-015-1267-0 5 14 1 11 "Humans|*Prolactinoma|*Dopamine|*Neoplasm Recurrence, Local|Bromocriptine|Pituitary Neoplasms|Dopamine Agonists|PRDM2 protein, human|*DNA-Binding Proteins|*Transcription Factors|*Nuclear Proteins|*Histone-Lysine N-Methyltransferase|Drug Resistance, Neoplasm|China" 11 DPRX 26360614 Nat Commun 2015 PMC4569847 10.1038/ncomms9207 29 0 7 4 "Humans|*Transcription Factors|*Retroelements|Embryonic Development|Blastocyst|Zygotes|Oocytes|Homeo Box Genes|Homeodomain Proteins|Blastomeres|Gene Expression Regulation, Developmental|Pluripotent Stem Cells|RNA, Messenger|Base Sequence|LEUTX protein, human" 11 DUSP18 26503224 Spinal Cord 2015 10.1038/sc.2015.171 6 0 1 121 "*Computational Biology|*Injury, Spinal Cord|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Profiling|Protein Interaction Mapping|Cluster Analysis|Gene Expression Regulation|MicroRNAs|Signal Transduction" 11 EFR3A 25622037 PLoS ONE 2015 PMC4306511 10.1371/journal.pone.0117345 0 0 0 48 "Animals|Mice|*Spiral Ganglion|*C57BL Mice|*Hair Cells, Auditory|Cochlea|Kanamycin|Nerve Degeneration|Neurons|Cell Survival|Furosemide|EFR3A protein, mouse|Membrane Proteins" 11 EFR3A 25598374 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2015 0 4 0 48 "Mice|Animals|*Spiral Ganglion|*Kanamycin|*Furosemide|*Cochlea|Hair Cells, Auditory|Evoked Potentials, Auditory, Brain Stem|Nerve Degeneration|Cell Survival|Disease Models, Animal|EFR3A protein, mouse|Membrane Proteins" 11 Fibin 26447881 PLoS ONE 2015 PMC4598026 10.1371/journal.pone.0139520 1 32 1 13 "IGF1 protein, human|*Insulin-Like Growth Factor I|*Tumor Necrosis Factor-alpha|*Kinetics|*Cell Differentiation|*Muscle Development|Myoblasts, Skeletal|Muscular Atrophy|*Gene Expression|Cell Line|Apoptosis|Muscle, Skeletal|Cells, Cultured" 11 Fibin 25736789 Invest. Ophthalmol. Vis. Sci. 2015 PMC4373543 10.1167/iovs.15-16388 5 0 0 13 "*Thrombin|*Extracellular Matrix|*Fibroblasts|*Cornea|Collagen|Corneal Keratocytes|Cells, Cultured|Cell Movement|Fibrin|Fibronectins|*Clustering" 11 gimap7 26596891 BMC Genomics 2015 PMC4657355 10.1186/s12864-015-2174-0 33 0 2 15 "Humans|Animals|Cattle|Female|Mice|*Alleles|Sequence Analysis, RNA|Allelic Imbalance|Gene Expression|Gene Expression Profiling|Polymorphism, Single Nucleotide|*Mammal|Chromosome" 11 gimap7 25849251 J Proteomics 2015 10.1016/j.jprot.2015.03.031 11 0 2 15 Animals|*Aeromonas salmonicida|*Oncorhynchus mykiss|*Transcriptome|*Spleen|*Proteomics|Furunculosis|*Aeromonas hydrophila|Fish Diseases|Gram-Negative Bacterial Infections|Proteome|Gene Ontology 11 HHATL 26608260 BMC Microbiol. 2015 PMC4660637 10.1186/s12866-015-0550-1 2 7 1 15 "*Saccharomyces cerevisiae|Hedgehog Proteins|*Proteomics|Saccharomyces cerevisiae Proteins|*Extracellular Matrix|Electrophoresis, Gel, Two-Dimensional|*Yeast, Dried|Proteome|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Signal Transduction" 11 HHATL 25589358 J. Basic Microbiol. 2015 10.1002/jobm.201400781 0 2 1 15 "Animals|*Saccharomyces cerevisiae|*Yeast, Dried|*Polysaccharides|Mannose|*Extracellular Matrix|Galactose|Glucose|Cell Wall|Molecular Weight|Electrophoresis, Polyacrylamide Gel|*Boron" 11 IGSF9B 26670097 Hum. Mutat. 2015 10.1002/humu.22943 16 0 2 45 "*MicroRNAs|*Parkinson Disease|*Binding Sites|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Alleles|Gene Expression" 11 IGSF9B 26575220 Transl Psychiatry 2015 PMC5068762 10.1038/tp.2015.169 19 3 1 45 "Humans|Animals|Mice|histone H3 trimethyl Lys4|*Histones|*Epigenomics|Bayes Theorem|Epigenesis, Genetic|*Gene Regulatory Networks|Methylation|Chromatin|Lysine|Transcription Start Sites|Cortex, Prefrontal|Transcription, Genetic|*Brain|Neurons|Transcriptomes" 11 MAATS1 25911616 Eur Radiol 2015 10.1007/s00330-015-3792-2 5 0 2 14 "Swine|Humans|Animals|*Perfusion|*Liver|*Genetic Therapy|Catheterization|*Procedure, Endovascular|Vena Cava, Inferior|Gene Expression" 11 MAMDC2 25860510 PLoS ONE 2015 PMC4393232 10.1371/journal.pone.0122285 19 6 2 11 "*Squamous Cell Carcinoma of Head and Neck|*Genes, Homeobox|MicroRNAs|Head and Neck Neoplasms|Gene Expression Regulation, Neoplastic|Carcinoma, Squamous Cell|Cell Proliferation|Cell Movement|Cell Line, Tumor|RNA, Messenger|Homeodomain Proteins|Apoptosis|Transcription Factors" 11 NBEAL1 26674333 Neurology 2015 PMC4731688 10.1212/WNL.0000000000002263 33 2 1 21 "Humans|*White Matter|*Stroke|Cerebral Small Vessel Diseases|Genome-Wide Association Study|*Leukoaraiosis|Polymorphism, Single Nucleotide|United Kingdom|Belgium|Italy|Australia" 11 OTOGL 25829320 Int. J. Pediatr. Otorhinolaryngol. 2015 10.1016/j.ijporl.2015.03.008 1 0 0 2 "Humans|*Hearing Loss, Sensorineural|*Chinese|Exome|Pedigree|Deafness|Hearing Loss|Genetic Association Studies|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|Mutation, Missense|Phenotype|Mutation|OTOGL protein, human|Membrane Proteins" 11 OTOGL 25719458 Genet. Med. 2015 10.1038/gim.2014.213 12 0 2 2 "Child|Humans|*Whole Exome Sequencing|*Hearing Loss, Sensorineural|Connexin 26|Connexins|Mutations|Pedigree|Hearing Loss|*Heredity" 11 PDZD8 25771112 Virology 2015 PMC4437853 10.1016/j.virol.2015.01.034 6 4 2 166 "Humans|Animals|Mice|*HIV-1|*HIV Infections|Capsid|Leukemia Virus, Murine|Cell Lines|Capsid Proteins" 11 SFSWAP 26420826 Nucleic Acids Res. 2015 PMC4666396 10.1093/nar/gkv952 12 41 1 225 "Humans|Animals|*Spliceosomes|*Ribonucleoprotein, U2 Small Nuclear|HeLa Cells|RNA Splicing|Splicing Factor U2AF|RNA Splicing Factors|RNA Precursors|Ribonucleoproteins|Nuclear Proteins|DNA-Binding Proteins|Transcription Factors|U2 small nuclear RNA|RNA, Small Nuclear|Splice Site, 3'|Protein Binding|Amino Acid Sequence|Alternative Splicing" 11 SHROOM4 26692240 Am. J. Med. Genet. A 2015 10.1002/ajmg.a.37519 4 1 0 42 "Child|Male|Humans|Female|*Duplications, Chromosome|Chromosomes, Human, X|Intellectual Disability|Comparative Genomic Hybridization|Phenotype|Facies|X Chromosome Inactivation|Genetic Association Studies|Developmental Disabilities|Genes, X-Linked|Pedigree|DNA Copy Number Variations|*Chromosome Structures|Genotype" 11 SHROOM4 26121239 PLoS ONE 2015 PMC4488298 10.1371/journal.pone.0131287 5 4 1 42 "Male|Female|Animals|Pregnancy|Mice|VDR protein, human|*Receptors, Calcitriol|*Pregnancy Outcome|Mice, Inbred C57BL|*Placenta|CYP24A1|Vitamin D|25-Hydroxyvitamin D3 1-alpha-Hydroxylase|Vitamin D Deficiency|Trophoblasts|Vitamins|Fetal Growth|Fetus|Gene Expression Regulation" 11 SHROOM4 25670966 Mol Cytogenet 2015 PMC4322561 10.1186/s13039-015-0107-x 5 0 0 42 Humans|*Dent Disease|Pedigree|Chloride Channels|*Chromosome Structures|Mutation 11 SPATA19 26464818 Cell J 2015 PMC4601867 10.22074/cellj.2015.8 8 0 0 10 "Humans|Male|*Up-Regulation|Carcinoma, Ductal, Breast|Cancer Biomarkers|Prognosis|Gene Expression Regulation, Neoplastic|*Transcriptional Activation|Antigens, Neoplasm|Seminal Plasma Proteins|RNA, Messenger|Membrane Proteins|Testis|*Breast Neoplasms|RHOXF2 protein, human|Homeodomain Proteins" 11 SPATA19 26265198 Mol. Reprod. Dev. 2015 10.1002/mrd.22536 5 0 0 10 "Mice|Humans|Animals|Male|Sperm Motility|*Sperm|Spermiogenesis|*Mitochondria|Spermatids|Infertility, Male|Fertility|Testis|Mice, Knockout|Mitochondrial Membranes|Mitochondrial Proteins|Haploid|SPATA19 protein, human|Seminal Plasma Proteins" 11 SPATA6 26464655 Int J Clin Exp Pathol 2015 PMC4583887 3 0 0 55 "Humans|Male|Testicular Germ Cell Tumor|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|*Spermatogenesis|Testis|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Apoptosis|SPATA6 protein, human|Cytoskeletal Proteins" 11 SPATA6 25605924 Proc. Natl. Acad. Sci. U.S.A. 2015 PMC4321249 10.1073/pnas.1424648112 23 0 1 55 "Humans|Male|Mice|Animals|Proteomics|*Sperm|Sperm Flagellum|Sperm Head|Male Sterility|Spermiogenesis|Sperm Motility|Testis|SPATA6 protein, human|Cytoskeletal Proteins" 11 TENM2 26449520 Genes Brain Behav. 2015 PMC4837474 10.1111/gbb.12259 2 2 0 25 "Mice|Animals|*Spatial Learning|*Mice, Inbred DBA|*Mice, Inbred C57BL|*Neuroanatomy|*Hippocampus|Maze Learning|Memory, Spatial|Quantitative Trait Loci|Neurons|Networks, Gene|Species Specificity" 11 TENM2 26212799 J. Clin. Periodontol. 2015 10.1111/jcpe.12437 13 0 1 25 "*Genome-Wide Association Study|*Chronic Periodontitis|Republic of Korea|*Cohort Studies|Genetic Association Studies|Polymorphism, Single Nucleotide|Risk Factors" 11 UFSP2 26428751 S. Afr. Med. J. 2015 10.7196/SAMJnew.7917 11 1 1 51 "*Hip Dislocation|Hip Dysplasia, Beukes Type|*Osteochondrodysplasias|*Mutation|*Hip Dislocation, Congenital|Pedigree|Genes, Dominant|Lod Score|*Joint Diseases|Genetic Linkage|Amino Acid Sequence|*Extended Family|Sequence Analysis, DNA|Cataract|Ubiquitins|Peptide Hydrolases" 11 UFSP2 26350515 Eur. J. Hum. Genet. 2015 PMC4930090 10.1038/ejhg.2015.186 30 0 1 51 "Child|Humans|*Vision Disorders|Low Vision|*Brain Diseases|Blindness, Cortical|Visual Acuity|Intellectual Disability|Forecasting|AMOT protein, human|Membrane Proteins|Intercellular Signaling Peptides and Proteins|PGAP1 protein, human|Phosphoric Monoester Hydrolases" 11 VMO1 25733190 Ecotoxicol. Environ. Saf. 2015 10.1016/j.ecoenv.2015.02.031 1 1 0 4 11 AFAP1L1 24723436 Cancer Med 2014 PMC4303145 10.1002/cam4.237 1 11 0 36 "VCL protein, human|*Vinculin|Neoplasm Recurrence, Local|*Cell Motility|*Colorectal Cancers|*Disease Progression|Microfilament Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Adaptor Proteins, Signal Transducing|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|siRNA|Anoikis|Spindle Cell Sarcomas|*Synapsins" 11 ANKAR 25154025 J. Chem. Neuroanat. 2014 10.1016/j.jchemneu.2014.08.003 0 0 0 1 "Female|Pregnancy|Guinea Pigs|Animals|CALB2 protein, human|Calretinin|*Laterodorsal Thalamic Nucleus|Parvalbumins|Calbindin-D28K|Anterior Thalamic Nuclei|Neurons|Immunofluorescence" 11 CDH20 24744704 Front Neuroanat 2014 PMC3978366 10.3389/fnana.2014.00018 1 1 0 17 "Animals|Chick Embryo|*Chicken|osteoblast cadherin|*Cadherins|CDH10 protein, human|*Spinal Cord|*Embryo, Mammalian|Neurogenesis|In Situ Hybridization|Gene Expression Regulation, Developmental" 11 CEACAM16 25080593 J. Neurosci. 2014 PMC4115139 10.1523/JNEUROSCI.1256-14.2014 21 0 2 3 "Mice|Animals|*Tectorial Membrane|Otoacoustic Emissions, Spontaneous|Hearing|Hair Cells, Auditory, Outer|Acoustic Stimulation|Extracellular Matrix Proteins|GPI-Linked Proteins|Mice, Knockout|Extracellular Matrix" 11 CLYBL 24532677 Ann. Rheum. Dis. 2014 10.1136/annrheumdis-2013-204591 16 0 1 323 "Humans|*Genome-Wide Association Study|*Rheumatoid Arthritis|HLA-DRB1 Chains|Citrulline|Autoantibodies|Peptides, Cyclic|*Peptides|Genetic Predisposition to Disease|Alleles|Case-Control Studies|Epitopes|Genotype|Smoking" 11 dchs2 25340762 PLoS Genet. 2014 PMC4207671 10.1371/journal.pgen.1004726 0 32 2 7 "Animals|Humans|Zebrafish|SOX9 protein, human|SOX9 Transcription Factor|Morphogenesis|Zebrafish Proteins|Cartilage|Chondrocytes|Embryonic Development|Gene Expression Regulation, Developmental|Cell Polarity|Cell Differentiation|Cadherins|*Signal Transduction" 11 dchs2 24898286 Pathol. Oncol. Res. 2014 10.1007/s12253-014-9804-8 5 0 0 7 "*Microsatellite Instability|*Frameshift Mutation|*Colorectal Cancers|CDH1 protein, human|*Cadherins|CDH10 protein, human|Stomach Neoplasms|DNA, Neoplasm|*Stomach|Polymorphism, Single-Stranded Conformational|Tumorigenesis|Mutation|Exons|Base Sequence|DNA Sequencing|Antigens, CD" 11 dchs2 26126179 Transl Psychiatry 2014 PMC4080317 10.1038/tp.2014.35 10 9 1 7 "Humans|*Neurofibrillary Tangles|*Alzheimer Disease|amyloid beta-protein (1-42)|Amyloid beta-Peptides|*Disease Progression|tau Proteins|Brain|Peptide Fragments|GRB14 protein, human|Adaptor Proteins, Signal Transducing" 11 DPCR1 25414627 Front Neurosci 2014 PMC4222236 10.3389/fnins.2014.00331 31 0 5 11 "Child|Humans|Genome-Wide Association Study|Depressive Disorder, Major|Bipolar Disorder|Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Attention Deficit Disorder with Hyperactivity|Autism Spectrum Disorder|Child Development Disorders, Pervasive|CSMD1 protein, human|Membrane Proteins|Anxiety Disorders|ANK3 protein, human|Ankyrins|AS3MT protein, human|Methyltransferases|TRIM26 protein, human|DNA-Binding Proteins" 11 DPCR1 24595008 PLoS ONE 2014 PMC3942432 10.1371/journal.pone.0090438 7 0 1 11 "Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Genome-Wide Association Study|*Incidence|*Major Histocompatibility Complex|Carcinoma, Squamous Cell|Chinese|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Case-Control Studies|Risk Factors|China" 11 DPRX 24506248 J. Neurosurg. 2014 10.3171/2014.1.JNS131292 13 0 3 4 "Humans|*Intracranial Pressure|*Traumatic Brain Injury|Intracranial Hypertension|Glasgow Coma Scale|Brain Injuries|Cerebrovascular Circulation|Monitoring, Physiologic|Retrospective Studies|Logistic Models|Prognosis" 11 DUSP18 24847354 Front Genet 2014 PMC4019850 10.3389/fgene.2014.00115 5 46 1 121 "*Proteomics|Phosphatidylinositol 3-Kinases|Phosphorylation|Substrate Specificity|Amino Acid Sequence|*Biochemical Phenomena|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Down-Regulation|Mass Spectrometry" 11 EFR3A 25380825 J. Cell. Sci. 2014 PMC4282049 10.1242/jcs.157495 10 3 2 48 "Animals|Humans|HEK293 Cells|*Palmitoylation|Isoproterenol|Phosphorylation|Cyclic AMP|Receptors, Adrenergic, beta|Signal Transduction|Receptor, Angiotensin, Type 1|*Membrane Proteins|Downregulation|Cytosol" 11 EFR3A 24875474 Nucleic Acids Res. 2014 PMC4081084 10.1093/nar/gku467 7 48 1 48 "Humans|*Transcription Factor|*Proteomics|RNA Polymerase II|*Gene Expression Regulation|Transcription Factors, TFII|Transcription, Genetic|DNA-Binding Proteins|Transcription Factor TFIID|Nuclear Proteins|Chromatin Immunoprecipitation|Transcription Start Site|Promoter Regions, Genetic|*Genomics|Protein Binding|Elongin A" 11 EFR3A 24860643 Mol Autism 2014 PMC4032628 10.1186/2040-2392-5-31 4 3 0 48 "Humans|Child|*Autism Spectrum Disorder|Genetic Predisposition to Disease|Nerve Tissue Proteins|Child Development Disorders, Pervasive|Polymorphism, Single Nucleotide|Mutation|Case-Control Studies|Synapse" 11 FAM136A 25305078 Hum. Mol. Genet. 2014 PMC4834881 10.1093/hmg/ddu524 26 1 4 96 "Humans|Rats|Animals|*Meniere Disease|Hearing Loss, Sensorineural|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Pedigree|Tinnitus|Mutation|Ear, Inner|Deafness|Missense Mutation|Proteins|Hearing Loss|Exon|Cochlea|DTNA protein, human|Neuropeptides|Dystrophin-Associated Proteins" 11 FAM83G 24832243 PLoS Genet. 2014 PMC4022470 10.1371/journal.pgen.1004370 20 1 7 143 Dogs|Animals|Genome-Wide Association Study|*Mutation|Haplotypes|Genotype|Pedigree|Phenotype|Genome|Base Sequence|Dog Diseases|Breeding 11 FAM83G 24554596 Open Biol 2014 PMC3938053 10.1098/rsob.130210 20 60 4 143 "BMPR1A protein, human|*Bone Morphogenetic Protein Receptors, Type I|*Signal Transduction|SMAD5 protein, human|Smad5 Protein|Bone Morphogenetic Proteins|SMAD4 protein, human|Smad4 Protein|Smad1 Protein|*Gene Expression Regulation|Phosphorylation|Transforming Growth Factor beta|Bone Morphogenetic Protein 2|TYRP1 protein, human|*Membrane Glycoproteins|Cell Nucleus|Intracellular Signaling Peptides and Proteins|Gene Expression" 11 Fibin 24986124 BMC Med. Genet. 2014 PMC4184381 10.1186/1471-2350-15-75 5 0 0 13 "Animals|Humans|*Homozygote|*Sequence Deletion|acylcarnitine|*Carnitine|gamma-Butyrobetaine Dioxygenase|Mixed Function Oxygenases|Aldehyde Oxidoreductases|RNA, Messenger|Mitochondria" 11 IGSF6 25116258 Neurol. Sci. 2014 10.1007/s10072-014-1889-z 0 0 0 88 "Humans|*Computational Biology|*Parkinson Disease|*Locus Coeruleus|*Gene Expression Profiling|*Microarray Analysis|Gene Ontology|Protein Interaction Maps|Gene Regulatory Networks|Profile, Gene Expression|Downregulation|Up-Regulation|Signal Transduction|LAPTM5 protein, human|Membrane Proteins" 11 IGSF6 24912583 BMC Genomics 2014 PMC4070558 10.1186/1471-2164-15-452 19 2 9 88 "Humans|Swine|Animals|Salmonella Infections, Animal|Salmonella typhimurium|Bacterial Shedding|Swine Diseases|Salmonella Food Poisoning|Feces|Gene Expression Profiling|Networks, Gene|Gene Expression|Interferon-gamma" 11 IGSF6 24475103 PLoS ONE 2014 PMC3903525 10.1371/journal.pone.0086306 6 0 2 88 "Humans|Leukocytes, Mononuclear|Dendritic Cells|HLA-A2|T-Lymphocytes, Cytotoxic|Antigen Presentation|Cancer Vaccines|Immunotherapy|Human Papilloma Virus|Monocytes|TREM2 protein, human|Membrane Glycoproteins|Interferon-gamma|Cell Differentiation|Tumor Cells, Cultured|MRPS11 protein, human|Ribosomal Proteins|Mitochondrial Proteins" 11 IQCG 24849454 PLoS ONE 2014 PMC4029791 10.1371/journal.pone.0098053 9 4 0 22 "Humans|Male|Mice|Animals|*Sperm Tail|Spermatids|Spermatogenesis|Spermatozoa|Acrosome|Infertility, Male|Testis|Flagellum|Axoneme|Cilia|Meiosis|Mice, Knockout|Cell Nucleus" 11 IQCG 24787902 Nat Commun 2014 10.1038/ncomms4811 3 3 0 22 "Animals|*Calmodulin|*Zebrafish|Calmodulin-Kinase|Calcium Signaling|*Hematopoiesis|Phosphorylation|Amino Acid Sequence|Cell Differentiation|Protein Binding|Leukemia, Myeloid, Acute" 11 KLHL14 25189415 Leukemia 2014 10.1038/leu.2014.264 38 0 3 34 "*Whole Exome Sequencing|*Mutations|Central Nervous System Neoplasms|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Non-Hodgkin|*Central Nervous System|INDEL Mutation|Genes, Regulator" 11 LRP11 25339519 J Ovarian Res 2014 PMC4210628 10.1186/s13048-014-0096-0 4 6 2 21 "Female|Cattle|Animals|*Receptors, Estrogen|*Granulosa Cells|Ovarian Follicle|Follicle Stimulating Hormone|Oestradiol|Fulvestrant|Gene Expression Regulation|Signal Transduction|*Hair Follicle" 11 LRP11 25262641 Psychiatry Res 2014 10.1016/j.psychres.2014.09.002 3 0 1 21 "Mice|Animals|*Gene Regulatory Networks|*Mice, Inbred DBA|*Mice, Inbred C57BL|Quantitative Trait Loci|*Low Density Lipoprotein Receptor-Related Protein-1|Phenotype|Hippocampus|*Biological Phenomena|Downregulation" 11 OTOGL 24663154 J. Anim. Sci. 2014 10.2527/jas.2013-7059 13 0 2 2 "Swine|Female|Animals|Italy|*Genome-Wide Association Study|Genotype|Sus scrofa|Breeding|Genome|Phenotype|Polymorphism, Single Nucleotide|Chromosomes|IGF2 protein, human|IGF-2" 11 OTOGL 24378291 Ear Hear 2014 PMC3999258 10.1097/AUD.0000000000000008 4 0 0 2 "Humans|*Phenotypes|*Mutations|Audiometry, Pure-Tone|Audiometry, Speech|Hearing Loss, Sensorineural|Pedigree|Hearing Loss|Membrane Glycoproteins|OTOGL protein, human|Membrane Proteins" 11 PDZD8 24554657 J. Virol. 2014 PMC3993830 10.1128/JVI.02945-13 17 1 4 166 Humans|*HIV-1|*Capsid|Virus Uncoating|*Capsid Proteins|Reverse Transcription|HIV Infections|Cyclophilin A|Host-Pathogen Interactions|Carrier Proteins|Cell Line|PDZ Domain 11 PLA2G12B 25488254 Vet Clin Pathol 2014 10.1111/vcp.12216 2 0 1 8 "Horses|Animals|Horse Diseases|Bronchoalveolar Lavage Fluid|Bronchoalveolar Lavage|Cytokines|Inflammation|*Respiration Disorders|RNA, Messenger" 11 PLA2G12B 25201034 BMC Res Notes 2014 PMC4167513 10.1186/1756-0500-7-617 3 6 1 8 "Humans|*Bevacizumab|*Vascular Endothelial Growth Factor A|Ranibizumab|Angiogenesis Inhibitors|Antibodies, Monoclonal, Humanized|Retinal Pigment Epithelium|Antibodies, Monoclonal|Age Related Macular Degeneration|Cells, Cultured|Cell Survival|Enzyme-Linked Immunosorbent Assay|*Signal Transduction|Epithelial Cells|Retinal Pigments" 11 SFSWAP 24920025 J. Neurophysiol. 2014 PMC4122729 10.1152/jn.00306.2014 31 0 3 225 Mice|Animals|*Vibration|*Cochlea|Basilar Membrane|Outer Hair Cells|Organ of Corti|Hearing|Acoustic Stimulation|*Physical Therapy Modalities|Biophysics 11 SFSWAP 24391519 PLoS Genet. 2014 PMC3879212 10.1371/journal.pgen.1004055 11 5 2 225 "Mice|Animals|JAG1 protein, human|Jagged-1 Protein|*Ear, Inner|Serrate-Jagged Proteins|Receptors, Notch|Intercellular Signaling Peptides and Proteins|Calcium-Binding Proteins|Membrane Proteins|Inner Hair Cells|Signal Transduction|Intracellular Signaling Peptides and Proteins|Outer Hair Cells|Gene Expression Regulation, Developmental|Cell Differentiation|Cochlea|SOXB1 Transcription Factors|*RNA Splicing|Homozygote" 11 SHROOM4 25425167 Am. J. Med. Genet. 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Genet. 2014 PMC4152767 10.1186/s12881-014-0090-9 1 5 0 47 "Humans|*Branchio-Oto-Renal Syndrome|Protein Tyrosine Phosphatases|*Endogenous Retroviruses|Intracellular Signaling Peptides and Proteins|Nuclear Proteins|Pedigree|Phenotype|Comparative Genomic Hybridization|Genome, Human|*Chromosome Structures|*Databases, Genetic" 11 SLCO5A1 24376674 PLoS ONE 2014 PMC3869781 10.1371/journal.pone.0083257 9 6 2 47 "Animals|Humans|HeLa Cells|Organic Anion Transport Polypeptides|Solute Carrier Organic Anion Transporter Family Member 1B3|Organic Anion Transporters, Sodium-Independent|Liver-Specific Organic Anion Transporter 1|Biological Transport|Xenopus laevis|Oocytes|RNA, Messenger|Gene Expression Profiling" 11 SPATA17 25353171 PLoS ONE 2014 PMC4213026 10.1371/journal.pone.0111308 1 3 1 6 "Mice|Animals|*Kidney Glomerulus|*Lipoprotein|*Aging|*Genetic Testing|Kidney|Phenotypes|*Kidney Diseases|RNA, Messenger" 11 UFSP2 25219498 Mol. Cell 2014 10.1016/j.molcel.2014.08.007 42 24 4 51 "*Transcriptional Activation|Tamoxifen|Estrogen Receptor alpha|Estrogen Antagonists|Oestradiol|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Estrogens|Promoter Regions, Genetic|EP300 protein, human|E1A-Associated p300 Protein" 11 UFSP2 24603482 PLoS Genet. 2014 PMC3945108 10.1371/journal.pgen.1004082 14 21 1 51 "Animals|Humans|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Genes, Helminth|Olfactory Receptor Neurons|Amino Acid Sequence|Receptors, Odorant|Cilia|Membrane Proteins|Endoplasmic Reticulum|Chemotaxis|Cysteine Proteases|Mutation|UFM1 protein, human|Proteins" 11 VMO1 25458700 Mol. Cell. Endocrinol. 2014 10.1016/j.mce.2014.10.015 4 2 2 4 11 VMO1 25257056 Invest. Ophthalmol. Vis. Sci. 2014 10.1167/iovs.14-14491 4 1 2 4 11 VMO1 25086240 J Proteomics 2014 10.1016/j.jprot.2014.07.024 15 3 2 4 11 36951 24054907 J Arthroplasty 2013 10.1016/j.arth.2013.07.048 1 0 0 0 "Humans|Knee Arthroplasty|Arthroplasty, Replacement, Hip|Knee Prosthesis|Hip Prosthesis|Osteoarthritis, Hip|*Registries|Reoperation|Osteoarthritis, Knee|Prosthesis Failure|Kaplan-Meier Estimate|*Longitudinal Studies|Knee Joint|Hospitals, Public" 11 36951 23594980 Rev Esp Cir Ortop Traumatol 2013 10.1016/j.recot.2012.10.003 2 0 0 0 "Knee Prosthesis|Arthroplasty, Replacement, Knee|Arthroplasty, Replacement, Hip|Hip Prosthesis|Reoperation|Prosthesis Failure|Registry|*Marketing|Product Surveillance, Postmarketing" 11 AFAP1L1 24291026 Gene 2013 10.1016/j.gene.2013.11.029 17 0 3 36 Child|Humans|*Intellectual Disability|Comparative Genomic Hybridization|DNA Copy Number Variations|Russia|Developmental Disabilities|Chromosome Aberrations|*Cohort Studies 11 AFAP1L1 23326307 PLoS ONE 2013 PMC3541374 10.1371/journal.pone.0049709 7 22 2 36 "SP3 protein, human|*Sp3 Transcription Factor|Sp1 Transcription Factor|Promoter Regions, Genetic|Mithramycin|*Sarcoma|Transcription Start Site|Electrophoretic Mobility Shift Assay|Binding Sites|Chromatin Immunoprecipitation|*Microfilament Proteins|DNA-Binding Proteins|Luciferase|*Neoplastic Processes|Cell Line, Tumor|Protein Binding|Transfection|*Soft Tissue Neoplasms" 11 ANKAR 24342567 Neuroscience 2013 10.1016/j.neuroscience.2013.12.015 0 0 1 1 Guinea Pigs|Animals|*Anterior Thalamic Nuclei|*Mammillary Bodies|*Calbindin|cocaine- and amphetamine-regulated transcript protein|Nerve Tissue Proteins|Calbindin 2|Neurons|Neuropile|Immunohistochemistry 11 AP3S2 23372846 PLoS ONE 2013 PMC3555946 10.1371/journal.pone.0055272 63 2 8 71 "Humans|*Diabetes Mellitus, Type 2|*miRNA|*Pancreatic beta Cell|*Pancreatic Islets|Illumina Sequencing" 11 CDH20 23301059 PLoS ONE 2013 PMC3534699 10.1371/journal.pone.0053310 20 3 3 17 "Humans|*Exome|*Adenoma|*Whole Exome Sequencing|*Cell Transformation, Neoplastic|*Mutations|*Tumorigenesis|Colorectal Neoplasms|Adenocarcinoma" 11 CLYBL 24334609 Hum. Mol. Genet. 2013 PMC3976331 10.1093/hmg/ddt624 10 0 1 323 Animals|Humans|*Malate Synthase|glyoxylic acid|Glyoxylates|propionyl-coenzyme A|Acyl Coenzyme A|Oxo-Acid-Lyases|Isocitrate Lyase|Acetyl-CoA|malic acid|Malates|Bacteria 11 CLYBL 23754956 PLoS Genet. 2013 PMC3674994 10.1371/journal.pgen.1003530 29 2 1 323 "Humans|*Vitamin B12|*Folate|Genome-Wide Association Study|Methylenetetrahydrofolate reductase deficiency|Methylenetetrahydrofolate Reductase (NADPH2)|*Base Sequence|Genotype|Polymorphism, Single Nucleotide|Homocystinuria|Muscle Spasticity|Psychotic Disorders|Iceland|ABCD4 protein, human|ATP-Binding Cassette Transporters|FUT6 protein, human|Fucosyltransferases|FOLR3 protein, human|Carrier Proteins" 11 EFR3A 23301059 PLoS ONE 2013 PMC3534699 10.1371/journal.pone.0053310 0 3 3 48 "Humans|*Exome|*Adenoma|*Whole Exome Sequencing|*Cell Transformation, Neoplastic|*Mutations|*Tumorigenesis|Colorectal Neoplasms|Adenocarcinoma" 11 FAM83G 23656696 BMC Res Notes 2013 PMC3663780 10.1186/1756-0500-6-189 8 0 0 143 "Humans|Mice|Animals|*Chromosomes, Human, Pair 11|*Mutation|Base Sequence|Chromosome Mapping|Homozygote|Amino Acid Sequence|DNA Primers|Crosses, Genetic|Cloning, Molecular|Polymerase Chain Reaction|Sequence Homology, Amino Acid" 11 FIBCD1 24293368 J. Biol. Chem. 2013 PMC3908420 10.1074/jbc.M113.520577 10 13 0 77 "*Fibrinogen|Binding Sites|ficolin|Lectins|Ligands|Protein Binding|TL-5A protein, Tachypleus tridentatus|Protein Structure, Tertiary|Protein Conformation|Amino Acid Sequence|Crystallography, X-Ray|Models, Molecular|Mutagenesis, Site-Directed|Chitin|*Hemostatics|Carrier Proteins|Polysaccharides" 11 gimap7 23454188 Structure 2013 10.1016/j.str.2013.01.014 18 4 3 15 "Humans|*GTPase Activators|GTPases|Hydrolysis|Protein Conformation|gephyrin|Membrane Proteins|Guanosine Triphosphate|Dimerization|Crystallography, X-Ray|Models, Molecular|Carrier Proteins|Catalysis|Binding Sites|Arginine" 11 IGSF9B 23751499 J. Cell Biol. 2013 PMC3678166 10.1083/jcb.201209132 26 38 2 45 11 IGSF9B 23417431 Neurochem. Res. 2013 10.1007/s11064-013-0999-y 8 0 0 45 11 IQCG 24362311 G3 (Bethesda) 2013 PMC3931569 10.1534/g3.113.009563 10 2 0 22 "Humans|Male|Mice|Animals|*Spermiogenesis|Spermatids|Spermatozoa|Infertility, Male|Sperm Head|Sperm Flagellum|Gene Expression Regulation|Flagella|Calmodulin|Mutation" 11 LYZL4 24013621 Asian J. Androl. 2013 PMC3854060 10.1038/aja.2013.93 6 0 2 5 "Male|Mice|Humans|Animals|Epididymis|Spermatozoa|Testis|Muramidase|Genitalia, Male|Amino Acid Sequence|Western Blots|Bacteriolysis|Recombinant Proteins|*Anti-Bacterial Agents|LYZL4 protein, human|LYZL6 protein, human" 11 MTG2 23396448 Nucleic Acids Res. 2013 PMC3616715 10.1093/nar/gkt079 20 2 3 47 "Animals|Humans|*Mitochondrial Ribosomes|GTP Phosphohydrolases|Mitochondria|TYRP1 protein, human|*Subunits, Large Ribosomal|Ribosomal Proteins|Protein Biosynthesis|*Membrane Glycoproteins|Amino Acid Sequence|HEK293 Cells" 11 OTOGL 23850727 Gene 2013 10.1016/j.gene.2013.06.044 10 0 2 2 "Child|Humans|*Codon, Nonsense|*Hearing Impairment|Nonsyndromic Deafness|Deafness|Hearing Loss, Sensorineural|Tectorial Membrane|Otoacoustic Emissions, Spontaneous|Mutations|Homozygote|Genotypes|Outer Hair Cells|Phenotype|Membrane Proteins|Membrane Glycoproteins|Polymorphism, Single Nucleotide|OTOGL protein, human" 11 SHROOM4 23871722 Am. J. Hum. Genet. 2013 PMC3738825 10.1016/j.ajhg.2013.06.013 83 0 8 42 "Humans|*Exome|Genes, X-Linked|*Mutations|Intellectual Disability|Whole Exome Sequencing|High-Throughput Nucleotide Sequencing|Pedigree|Genes, Regulator|IGBP1 protein, human|Intracellular Signaling Peptides and Proteins|Cohort Studies|CLIC2 protein, human|Chloride Channels|CNKSR2 protein, human|Adaptor Proteins, Signal Transducing|NAA10 protein, human|N-Terminal Acetyltransferase A|N-Terminal Acetyltransferase E" 11 SPATA17 23549274 Eur. J. Hum. Genet. 2013 PMC3831074 10.1038/ejhg.2013.58 10 0 1 6 "Humans|Mice|Animals|VACTERL association|DNA Copy Number Variations|Limb Deformities, Congenital|Heart Defects, Congenital|Anus, Imperforate|Spine|Trachea|Esophagus|Anal Canal|Anorectal Malformations|Esophageal Atresia|Tracheoesophageal Fistula|Kidney|Phenotype|Abnormalities, Multiple|Radius|Renal Adysplasia|*Chromosome Structures" 11 SPATA19 23721730 J. Hazard. Mater. 2013 10.1016/j.jhazmat.2013.04.046 16 1 0 10 "Humans|Male|Mice|Animals|*Testis|titanium dioxide|*Titanium|*Spermatogenesis|Sperm|*Gene Expression Regulation|Metal Nanoparticles|SPATA19 protein, human|Mitochondrial Proteins|Seminal Plasma Proteins|PSMC3IP protein, human|Nuclear Proteins|Trans-Activators|SRD5A2 protein, human|Membrane Proteins|3-Oxo-5-alpha-Steroid 4-Dehydrogenase|Tnp2 protein, mouse|Adam3 protein, mouse" 11 SVOPL 24247273 Epigenetics 2013 PMC4053454 10.4161/epi.27160 14 6 2 5 "Humans|*Uniparental Disomy|*Chromosomes, Human, Pair 7|Genomic Imprinting|Silver-Russell Syndrome|DNA Methylation|GRB10 protein, human|GRB10 Adaptor Protein|Allele|Databases, Genetic|Genes, Homeobox|PON1 protein, human|Aryldialkylphosphatase|HOXA4 protein, human|Homeodomain Proteins" 11 SVOPL 23894296 PLoS ONE 2013 PMC3722232 10.1371/journal.pone.0068215 3 3 0 5 "Animals|Mice|Synaptic Vesicle|Synaptotagmins|Neurotransmission|Neurons|Exocytosis|Nerve Tissue Proteins|Mice, Knockout|Membrane Glycoproteins|Cells, Cultured" 11 TENM2 24344830 BMC Evol. Biol. 2013 PMC3878729 10.1186/1471-2148-13-273 9 0 0 25 "Horses|Animals|*Altitude|*Genome-Wide Association Study|*Acclimatization|*Adaptation, Physiological|*Genome|Selection, Genetic|Hypoxia|Basic Helix-Loop-Helix Transcription Factors|Polymorphism, Single Nucleotide" 11 AFAP1L1 22649524 PLoS ONE 2012 PMC3359349 10.1371/journal.pone.0037384 12 4 1 36 "*Genome-Wide Association Study|*Depressive Disorder, Major|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genotype|Cytoskeletal Proteins|Neuropeptides|Cohort Studies|Australia" 11 AP3S2 23029454 PLoS ONE 2012 PMC3459833 10.1371/journal.pone.0046263 13 4 1 71 "Humans|*Polymorphism, Single Nucleotide|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Genetic Loci|Genotype|Case-Control Studies|DUSP9 protein, human|Dual-Specificity Phosphatases|Mitogen-Activated Protein Kinase Phosphatases" 11 CEACAM16 22544735 J. Biol. Chem. 2012 PMC3381124 10.1074/jbc.M111.320481 19 0 1 3 "Mice|Animals|*Tectorial Membrane|CEACAM5 protein, human|*Carcinoembryonic Antigen|*GPI-Linked Proteins|*Hearing Impairment|*Cell Adhesion Molecules|Hearing|Outer Hair Cells|Deafness, Autosomal Dominant 4|Hearing Loss, Sensorineural|Extracellular Matrix Proteins|Deafness|*Cell Adhesion|Acoustic Stimulation|Membrane Proteins|*Mammal" 11 CLYBL 22367966 Hum. Mol. Genet. 2012 10.1093/hmg/dds062 24 0 1 323 "Male|Humans|*Genome-Wide Association Study|*Vitamin B12|Single Nucleotide Polymorphism|Asian|Genetic Predisposition to Disease|Anemia, Pernicious|Genotype|Case-Control Studies|*Ethnic Groups|FUT6 protein, human|Fucosyltransferases" 11 dchs2 22960237 Bone 2012 10.1016/j.bone.2012.08.127 4 0 0 7 "Male|Humans|Female|*Genome-Wide Association Study|*Compressive Strength|Chinese|SNPs|European Continental Ancestry Group|Haplotypes|*Stearoyl-CoA Desaturase|Genotype|Fatty Acid Desaturases|Osteoporosis|Genome, Human|*Cadherins|Phenotype" 11 DUSP18 22792334 PLoS ONE 2012 PMC3394735 10.1371/journal.pone.0040457 9 11 1 121 "Animals|Male|Oligodendrocyte|Myelin|*Neurogenesis|Cell Differentiation|Myelin Basic Protein|Multiple Sclerosis|Signal Transduction|Cells, Cultured|RNA, Messenger|RNA Interference|*Genomics" 11 Fibin 23127594 Gene 2012 10.1016/j.gene.2012.10.069 3 0 0 13 "Animals|Chick Embryo|*TGFbeta|*Myofibroblasts|*Chicken|Receptors, Transforming Growth Factor beta|Receptor, Transforming Growth Factor-beta Type II|*Gene Expression|Signal Transduction|Smad2 Protein|Protein-Serine-Threonine Kinases|Receptor, Transforming Growth Factor-beta Type I|Fibrosis|Activin Receptors, Type I|Fibroblasts|DNA-Binding Proteins|Trans-Activators|Actins|Cells, Cultured|Wound Healing" 11 LRP11 23185754 Zhongguo Zhong Xi Yi Jie He Za Zhi 2012 4 0 0 21 "Humans|*Gastritis, Atrophic|*Syndrome|Gastritis|Medicine, Chinese Traditional|Oligonucleotide Array Sequence Analysis|*Energy Metabolism|Gastric Mucosa|*Mucositis|Gene Expression|*Precancerous Conditions|*Musculoskeletal Diseases|Case-Control Studies" 11 MAATS1 22551925 Arch. 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Genet. 2012 PMC3487139 10.1016/j.ajhg.2012.09.011 38 0 4 2 "Animals|Nonsyndromic sensorineural hearing loss|*Hearing Loss, Sensorineural|*Ear, Inner|*Mutations|Deafness|Homozygote|Cochlea|Pedigree|Membrane Proteins" 11 PLA2G12B 22912808 PLoS ONE 2012 PMC3422231 10.1371/journal.pone.0043139 8 7 0 8 "Mice|Animals|*Ethylnitrosourea|*Cholesterol, HDL|*Mutagenesis|Mutation|Chromosome Mapping|Mice, Inbred C57BL|DNA Mutational Analysis|Crosses, Genetic|Phenotype|Mutagens|Genetic Linkage|Splice Site, 3'|Cholesterol|Exon" 11 SLAIN2 23251535 PLoS ONE 2012 PMC3520847 10.1371/journal.pone.0051442 31 9 4 169 "Humans|*HeLa Cells|EB1 microtubule binding proteins|*Microtubule-Associated Proteins|CKAP5 protein, human|Microtubules|*Interphase|Tubulin|Protein Binding|Chromosome Segregation|Binding Sites" 11 SLAIN2 23077057 J. 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Cell Biol. 2011 PMC3085893 10.1016/j.ejcb.2010.11.016 18 9 4 36 "Humans|CTTN protein, human|*Cortactin|*Podosomes|*Adaptor Proteins, Signal Transducing|Actin|Phosphoproteins|SH3 Domain|Actin Filament|Amino Acid Sequence|RNA, Small Interfering|AFAP1L1 protein, human|Microfilament Proteins" 11 AP3S2 21874001 Nat. Genet. 2011 PMC3773920 10.1038/ng.921 195 2 21 71 "Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Asian Continental Ancestry Group|SNPs|Genetic Predisposition to Disease|Genetic Loci|Genetic Association Studies|Case-Control Studies|Singapore|Pakistan|London" 11 CEACAM16 22064717 Infect. Immun. 2011 PMC3255650 10.1128/IAI.05702-11 36 2 3 3 "Humans|Mice|Animals|*Neisseria gonorrhoeae|CEACAM5 protein, human|*Carcinoembryonic Antigen|*Neutrophils|CD66 antigens|*Cell Adhesion Molecules|CEACAM6 protein, human|Gonorrhea|Antigens, CD|*GPI-Linked Proteins|Neisseria|Bacterial Adhesion|Bacterial Outer Membrane Proteins" 11 CEACAM16 21368133 Proc. Natl. Acad. Sci. U.S.A. 2011 PMC3054008 10.1073/pnas.1005842108 51 0 2 3 "Animals|CEACAM5 protein, human|*Carcinoembryonic Antigen|*Hearing Loss|Nonsyndromic Deafness|*Deafness|Deafness, Autosomal Dominant 4|*Hearing Loss, Sensorineural|Tectorial Membrane|*Extracellular Matrix Proteins|Cochlear Outer Hair Cells|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Genes, Dominant|Myosin Heavy Chains|Mutation|Pedigree|GPI-Linked Proteins|Cell Adhesion Molecules" 11 dchs2 22005931 Mol. Psychiatry 2011 PMC3262952 10.1038/mp.2011.135 36 1 0 7 *Genome-Wide Association Study|*Alzheimer Disease|Single Nucleotide Polymorphisms|Apolipoproteins E|Genetic Predisposition to Disease|Genotype|Age of Onset|Case-Control Studies 11 DPCR1 22152429 Respir Care 2011 10.4187/respcare.01480 2 0 2 11 "Humans|Diffuse panbronchiolitis|Republic of Korea|*Asthma, Aspirin-Induced|*Bronchiolitis|*Haemophilus Infections|Genetic Predisposition to Disease|Haplotypes|Polymorphism, Single Nucleotide|*Asthma|Linkage Disequilibrium|Asian Continental Ancestry Group|Gene Frequency|Forced Expiratory Volume|Genotype|Aspirin|DPCR1 protein, human" 11 DPRX 21679462 BMC Evol. Biol. 2011 PMC3141429 10.1186/1471-2148-11-169 28 0 7 4 "Animals|Mice|Humans|*Genes, Homeobox|*Vertebrate|Evolution, Molecular|Phylogeny|Amino Acid Sequence|Gene Expression Regulation|Embryonic Development" 11 Fibin 21615908 BMC Biochem. 2011 PMC3115872 10.1186/1471-2091-12-26 2 19 1 13 "Humans|Animals|Amino Acid Sequence|Base Sequence|Gene Expression Regulation|Promoter Regions, Genetic|Zebrafish|Conserved Sequence|RNA, Messenger|Transfection" 11 gimap7 21925515 Life Sci. 2011 PMC3264544 10.1016/j.lfs.2011.08.016 3 6 0 15 "Rats|Animals|*Rats, Inbred BB|*B Cells|Lymphopenia|T-Lymphocytes|*Gene Expression|Diabetes Mellitus, Type 1|GTP-Binding Proteins|*Cell Count|Gimap5 protein, rat" 11 LRP11 21947380 Diabetologia 2011 10.1007/s00125-011-2295-1 19 0 1 21 "Humans|*Pancreatic Islet|*Progenitor Cell|*Cell Separation|Cell Differentiation|*Biomarkers|Pancreas|Basic Helix-Loop-Helix Transcription Factors|Homeodomain Proteins|Pancreatic beta Cell|Nerve Tissue Proteins|Flow Cytometry|Cells, Cultured" 11 LYZL4 22110709 PLoS ONE 2011 PMC3217008 10.1371/journal.pone.0027659 6 0 1 5 "Male|Rats|Mice|Animals|lysozyme C, human|*Muramidase|Testis|Epididymis|Spermatozoa|Genitalia, Male|Amino Acid Sequence|SLLP1 protein, mouse|Isoantigens|Seminal Plasma Proteins" 11 LYZL4 21444326 Acta Biochim. Biophys. Sin. (Shanghai) 2011 10.1093/abbs/gmr017 12 0 1 5 "Male|Mice|Animals|*Sperm|Epididymis|Testis|Sperm-Ovum Interactions|Fertilization|Seminal Plasma Proteins|Sequence Alignment|Recombinant Proteins|Lysozyme|Cloning, Molecular|Amino Acid Sequence|Blotting, Western|Fertilization in Vitro|Antibodies|Bacteriolysis" 11 MTG2 21608104 Birth Defects Res. Part A Clin. Mol. Teratol. 2011 PMC3193386 10.1002/bdra.20821 8 1 1 47 "Humans|*Tracheoesophageal Fistula|Esophageal Atresia|Genitourinary Tract Anomalies|*Urogenital Abnormalities|Limb Deformities, Congenital|Esophagus|Trachea|Abnormalities, Multiple|Heart Defects, Congenital|Spine|*Chromosome Structures" 11 PDZD8 21549406 Virology 2011 10.1016/j.virol.2011.04.006 12 2 1 166 "moesin|*Herpesvirus 1, Human|*Microfilament Proteins|radixin|*Cytoskeletal Proteins|ezrin|*Cytoskeleton|Membrane Proteins|Actin|Phosphoproteins|Plasma Membrane|siRNA|*Transcription Factors|Cell Line|Phosphorylation|Infections" 11 SLAIN2 21646404 J. Cell Biol. 2011 PMC3115796 10.1083/jcb.201012179 56 44 6 169 "Animals|*Microtubule|CKAP5 protein, human|Microtubule-Associated Proteins|*Interphase|Tubulin|Amino Acid Sequence|Mitosis|Models, Molecular|Neoplasm Proteins" 11 SLCO5A1 21278488 Cancer Biol. Ther. 2011 10.4161/cbt.11.6.14533 23 0 4 47 "Humans|*Biological Transport|Organic Anion Transport Polypeptides|Cancer|*Membrane Transport Proteins|Estrogens|mRNA|Anticancer Agents|Cells, Epithelial" 11 SLCO5A1 24179389 Biomark Cancer 2011 PMC3791916 10.4137/BIC.S7151 6 5 0 47 "*Small Cell Lung Carcinoma|satraplatin|*Drug Resistance, Neoplasm|*Organoplatinum Compounds|*Organic Anion Transporters|Lung Neoplasms|Cell Line, Tumor|Biological Transport" 11 SPATA17 21901812 Environ. Toxicol. 2011 10.1002/tox.20767 4 0 0 6 "Animals|Male|Female|decabromobiphenyl ether|*Halogenated Diphenyl Ethers|*Cyprinidae|*Thyroid Hormones|Flame Retardants|*Spermatogenesis|Thyroid Gland|Iodide Peroxidase|*Transcription, Genetic|Endocrine Disruptors|Thyroid Hormone Receptor|Liver|mRNA|Testis|Larvae|Water Pollutants, Chemical" 11 SPATA17 21679429 BMC Genomics 2011 PMC3146955 10.1186/1471-2164-12-318 59 0 10 6 "Cattle|Animals|*Haplotypes|Breeding|Selection, Genetic|Genome|Genetics, Population|Phenotype|Genotype|Genomics|Homozygote|Polymorphism, Single Nucleotide" 11 TENM2 21724987 Proc. Natl. Acad. Sci. U.S.A. 2011 PMC3141932 10.1073/pnas.1019434108 91 0 5 25 "Rats|Animals|alpha-latrotoxin receptor|Synapses|Receptors, Peptide|Synaptic Transmission|Neurons|Hippocampus|Nerve Tissue Proteins|*Carrier Proteins|Receptors, Cell Surface|Receptors, G-Protein-Coupled|*Ligands|*Signal Transduction|Neurogenesis" 11 UFSP2 21896847 Invest. Ophthalmol. Vis. Sci. 2011 10.1167/iovs.10-6581 7 0 0 51 "*Glaucoma, Primary Open Angle|Lod Score|Eye Proteins|Pedigree|Cytoskeletal Proteins|Glycoproteins|Genetic Linkage|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Glaucoma|Haplotypes" 11 UFSP2 21228277 J. Biol. Chem. 2011 PMC3060479 10.1074/jbc.M110.172171 14 2 1 51 "Mice|Animals|Proteins|Amino Acid Sequence|Crystallography, X-Ray|Binding Sites|Ubiquitins|Cysteine Endopeptidases|Cysteine Protease|Endoplasmic Reticulum|Models, Molecular" 11 VMO1 22025569 Invest. Ophthalmol. Vis. Sci. 2011 10.1167/iovs.11-8301 5 0 2 4 11 VMO1 21293736 Mol. Vis. 2011 PMC3032277 3 0 0 4 11 ANKAR 20648054 Eur. J. Hum. Genet. 2010 PMC3002852 10.1038/ejhg.2010.105 9 0 0 1 "Humans|*Haploinsufficiency|*Phenotype|Ehlers-Danlos Syndrome, Vascular Type|*Aortic Dissection|Marfan Syndrome|Mutations|Collagen Type III|Pedigree|TGFBR2 protein, human|TGFBR2|TGFBR1 protein, human|TGFBR1|Cohort Studies|MSTN protein, human|Myostatin|COL3A1 protein, human|ORMDL1 protein, human|Membrane Proteins" 11 AP3S2 20966410 Stroke 2010 PMC3004531 10.1161/STROKEAHA.110.596981 15 0 2 71 "Humans|*Genetic Linkage|*Plaque, Atherosclerotic|Carotid Artery Diseases|Genetic Association Studies|*Hispanics|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|West Indies|Caribbean|Genetic Loci|Phenotype|Risk Factors" 11 DPCR1 20981447 Hum. Genet. 2010 10.1007/s00439-010-0906-4 15 1 0 11 "Humans|Diffuse panbronchiolitis|*Mucin|*Bronchiolitis|*Haemophilus Infections|HLA-B Antigens|HLA-A11 Antigen|Histocompatibility Antigens Class I|MUC1 protein, human|*Mucin-1|Allele|*Cloning, Molecular|Asians|Genetic Predisposition to Disease|Gene Frequency|Single Nucleotide Polymorphism|DPCR1 protein, human" 11 DPCR1 20398667 Gastroenterology 2010 PMC2917327 10.1053/j.gastro.2010.04.008 50 0 4 11 "Humans|*Stomach Neoplasms|*Prognosis|*Metaplasia|*Stomach|CDH17 protein, human|*Cadherins|TFF2 protein, human|Trefoil Factor-2|Gastric Mucosa|*Gene Expression Profiling|spasmolytic polypeptide|Peptides|Precancerous Conditions|*Microarray Analysis|Intercellular Signaling Peptides and Proteins|Biomarkers, Tumor" 11 FCRL6 20933011 Immunol. 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Res. 2010 PMC2859711 10.1161/CIRCRESAHA.109.207753 36 22 1 88 "Mice|Animals|delta catenin|*Catenins|Cadherins|Adherens Junctions|Capillary Permeability|Antigens, CD|Endothelial Cells|Cell Adhesion|Endothelium, Vascular|Endocytosis|Cells, Cultured|Protein Binding|Phosphorylation" 11 MAATS1 20384945 J Sex Med 2010 PMC3163605 10.1111/j.1743-6109.2010.01749.x 15 50 1 14 "Male|Humans|TGFB1 protein, human|*Transforming Growth Factor beta1|*Pentoxifylline|*Down-Regulation|Peyronie Disease|*Fibroblasts|Penis|Cells, Cultured|Transforming Growth Factors" 11 PDZD8 20573829 J. Virol. 2010 PMC2919035 10.1128/JVI.00843-10 14 1 3 166 Humans|Human Immunodeficiency Virus Type 1|gag Protein|HIV Infections|Virus Replication|*Retroviridae Infections|Protein Binding|Carrier Proteins|Virus Entry|Cell Line 11 SHROOM4 20613765 J. Hum. Genet. 2010 10.1038/jhg.2010.74 17 1 1 42 "Humans|*Comparative Genomic Hybridization|*Intellectual Disability|Japan|Mental Retardation, X-Linked|*DNA Copy Number Variations|Chromosomes, Human, X|IL1RAPL1 protein, human|Interleukin-1 Receptor Accessory Protein|Gene Dosage|Chromosome Aberrations|Pedigree|Mutations|PQBP1 protein, human|Carrier Proteins|Nuclear Proteins|REPS2 protein, human|Intracellular Signaling Peptides and Proteins" 11 SLCO5A1 20602915 Am. J. Hum. Genet. 2010 PMC2896765 10.1016/j.ajhg.2010.05.012 8 2 1 47 "Humans|Adult|Female|Pregnancy|Mesomelia-synostoses syndrome|*Limb Deformities, Congenital|*Synostoses|*Abnormalities, Multiple|*Chromosome Structures|Phenotype|Oligonucleotide Array|Gene Deletion|In Situ Hybridization, Fluorescence|Syndrome|SULF1 protein, human|Sulfotransferases" 11 SPATA17 21108043 Mol. Biol. Rep. 2010 10.1007/s11033-010-0511-6 1 1 0 6 "Humans|Male|Female|Animals|*Zebrafish|GC 1 compound|*Spermatogenesis|Testis|Amino Acid Sequence|*Apoptosis|Spermatocyte|Cloning, Molecular|Proteins|DNA, Complementary|Base Sequence|Northern Blot|Introns|Gene Expression Profiling|Open Reading Frame|Exons" 11 SPATA19 20682177 Arch. Med. Res. 2010 10.1016/j.arcmed.2010.04.003 15 0 1 10 "Humans|Male|*Testis|*Prostate Cancer|Prostate-Specific Antigen|Prostatic Hyperplasia|Cancer Biomarkers|Antigens, Neoplasm|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|RNA, Messenger|Specificity|SPATA19 protein, human|Mitochondrial Proteins|Seminal Plasma Proteins|LEMD1 protein, human" 11 CDH20 20028529 BMC Neurosci 2009 PMC2811116 10.1186/1471-2202-10-153 11 0 1 17 "Animals|*Ferrets|osteoblast cadherin|*Cadherins|In Situ Hybridization|Neurogenesis|Gene Expression Regulation, Developmental|Cell Communication|Retina" 11 DUSP18 19228121 Biochem. J. 2009 10.1042/bj20082234 249 4 21 121 "*Dual-Specificity Phosphatases|Mitogen-Activated Protein Kinase Phosphatases|c-jun N-Terminal Kinase|Protein Phosphatases|Signal Transduction|MAP Kinase Signaling System|Extracellular Signal Regulated Kinases|Phosphorylation|Phosphotyrosine|Substrate Specificity|RASGRF1 protein, human|ras-GRF1" 11 FAM136A 19563808 Gastroenterology 2009 PMC2785077 10.1053/j.gastro.2009.06.050 27 3 1 96 "Animals|*Zebrafish|Zebrafish Proteins|Animals, Genetically Modified|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Developmental|Gene Expression Profiling|In Situ Hybridization|Transcriptome|Organogenesis|Larva|Green Fluorescent Proteins|Gastrointestinal Tract" 11 FIBCD1 19892701 J. Biol. Chem. 2009 PMC2801251 10.1074/jbc.M109.061523 13 5 1 77 "TL-5A protein, Tachypleus tridentatus|Lectins|Binding Site|ficolin|Ligands|Protein Binding|Chitin|Amino Acid Sequence|Fibrinogen|*Hydrophobic and Hydrophilic Interactions|Acetylation|Carbohydrates" 11 FIBCD1 19710473 J. Immunol. 2009 10.4049/jimmunol.0901526 29 2 2 77 "Animals|*Chitin|*Protein Binding|Ligands|Fungi|Receptors, Cell Surface|Amino Acid Sequence|Carrier Proteins|Gastrointestinal Tract|*Biophysical Phenomena" 11 IGSF6 19296339 Int. J. Radiat. Biol. 2009 10.1080/09553000902748609 11 2 0 88 "Mice|Animals|*Protons|*Gene Expression|Dose-Response Relationship, Radiation|Spleen|CD4-Positive T-Lymphocytes|Whole-Body Irradiation|Radiation, Ionizing|Mice, Inbred C57BL" 11 KLHL14 19535332 J. Biol. Chem. 2009 PMC2755898 10.1074/jbc.M109.004838 14 0 0 34 "TOR1A protein, human|*Molecular Chaperones|*Dystonia|*Dystonic Disorders|Endoplasmic Reticulum|Carrier Proteins|Mutation|Protein Binding|ATPases|Cell Line|*Transcription Factors" 11 LRP11 19760173 Neurochem. Res. 2009 10.1007/s11064-009-0054-1 11 0 0 21 "*Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Amyloid beta-Protein Precursor|Presenilin-1|Amyloid beta-Peptides|Alzheimer Disease|*Protein Transport|Membrane Glycoproteins|SORL1 protein, human|Membrane Transport Proteins|Lysosomes|LDL-Receptor Related Proteins" 11 MAMDC2 19343044 J. Hum. Genet. 2009 10.1038/jhg.2009.30 12 0 0 11 "Child|Humans|Kabuki syndrome|Comparative Genomic Hybridization|*Abnormalities, Multiple|*Karyotyping|*Vestibular Diseases|*Hematologic Diseases|*Face|Mental Retardation|Chromosome Aberrations|Oligonucleotide Array|Developmental Disabilities|In Situ Hybridization, Fluorescence|Syndrome|*Mutation|Cleft Palate" 11 SHROOM4 19384856 Dev. Dyn. 2009 PMC2699254 10.1002/dvdy.21942 20 1 1 42 "Animals|Xenopus laevis|*Morphogenesis|Xenopus Proteins|Epithelium|Cells, Epithelial|Embryo, Nonmammalian|Microfilament Proteins|Gene Expression Regulation, Developmental|In Situ Hybridization|Oocytes|mRNA" 11 SPATA17 19680270 J. Hum. Genet. 2009 10.1038/jhg.2009.74 13 0 1 6 "Humans|*Genome-Wide Association Study|Japan|*Anorexia Nervosa|*Microsatellite Markers|Linkage Disequilibrium|Haplotypes|Genotype|Gene Frequency|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Chromosome Mapping|Alleles|Case-Control Studies|Bulimia Nervosa|Exon" 11 SPATA17 19483714 Asian J. 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Cancer 2008 PMC2243149 10.1038/sj.bjc.6604184 28 3 1 8 "Humans|*Secreted Phospholipases A2|Colon Cancers|*Adenocarcinomas|*Colorectal Cancer|Colon|Immunohistochemistry|*Biomarkers|PLA2G3 protein, human|Group III Phospholipases A2|PLA2G10 protein, human|Group X Phospholipases A2|PLA2G2D protein, human|Group II Phospholipases A2" 11 TM2D3 18194513 BMC Med. Genet. 2008 PMC2248164 10.1186/1471-2350-9-2 9 0 0 31 "Humans|Child|*Chromosome 2|Chromosome Deletion|Comparative Genomic Hybridization|Chromosome Banding|Mental Retardation|In Situ Hybridization, Fluorescence|Developmental Disabilities|Translocation, Genetic|*Chromosome Structures|*Syndrome|Growth Disorders" 11 UFSP2 18321862 J. Biol. Chem. 2008 10.1074/jbc.M708756200 17 1 0 51 "Mice|Animals|Proteins|Amino Acid Sequence|Crystallography, X-Ray|Binding Sites|Ubiquitin-Like Proteins|Cysteine Endopeptidases|Papain|Sequence Homology, Amino Acid|Substrate Specificity|Models, Molecular|Ubiquitin|Proteases|Catalysis" 11 36951 18091811 Opt Lett 2007 10.1364/ol.23.001444 0 0 0 0 Computer Simulation|*Heterocyclic Compounds|Carmustine|Cytarabine|Etoposide|Joint Dislocations 11 FCRL6 17356879 Immunogenetics 2007 10.1007/s00251-007-0208-8 9 0 0 6 "Female|Pregnancy|Animals|Dogs|Phylogeny|*Vertebrates|*Species Specificity|*Receptors, Fc|Mammals|Evolution, Molecular|Amino Acid Sequence|Genome|Marsupials|Exons|Cloning, Molecular|Opossums|Chicken" 11 FCRL6 17213291 Blood 2007 10.1182/blood-2006-06-030023 12 2 1 6 "Humans|*HIV-1|CD8-Positive T-Lymphocytes|*HIV Infections|Viral Load|CD4-Positive T-Lymphocytes|Lymphocyte Activation|Natural Killer Cells|Immunity, Cellular" 11 Fibin 17196583 Dev. Biol. 2007 10.1016/j.ydbio.2006.11.041 12 2 0 13 "Humans|Mice|Animals|*Zebrafish|*Animal Fins|*Lateral Plate Mesoderm|Zebrafish Proteins|Embryo, Nonmammalian|T-Box Domain Proteins|Gene Expression Regulation, Developmental|WNT2B protein, human|Wnt Proteins|Retinoic Acid|Signal Transduction|Fibroblast Growth Factors|Morpholinos|Oligonucleotides, Anti-Sense|Glycoproteins" 11 IQCG 18084320 Oncogene 2007 10.1038/sj.onc.1210999 9 8 0 22 "nuclear pore complex protein 98|*Translocation, Genetic|*Leukemia, Myeloid, Acute|Nuclear Pore Complex Proteins|*Leukemia, Biphenotypic, Acute|Oncogene Proteins, Fusion|*Lymphoid Leukemia, Acute|Amino Acid Sequence|Base Sequence|*Acute Disease|In Situ Hybridization, Fluorescence" 11 LRP11 17719698 Neurochem. Int. 2007 10.1016/j.neuint.2007.06.020 7 0 0 21 *Alzheimer Disease|alpha Secretase|Amyloid beta-Protein Precursor|Brain|Cell Signaling|Protein Transport|Cell Line|Lipoproteins 11 SPATA19 17360959 Biol. Reprod. 2007 10.1095/biolreprod.106.058735 12 0 3 10 "Male|Mice|Animals|*Sperm Tail|*Epididymis|Spermatozoa|Sperm Maturation|*Carrier Proteins|Spermatogenesis|Cytoplasm|3'-(1-butylphosphoryl)adenosine|Golgi Apparatus|Mitochondria|Cell Nucleus|Proteins|*Complement Factor B|Gopc protein, mouse" 11 SVOPL 17714910 Genomics 2007 10.1016/j.ygeno.2007.03.017 30 0 3 5 "Rats|Animals|Humans|Mice|Phylogeny|*Biological Transport|*Membrane Transport Proteins|Amino Acid Sequence|Sequence Homology, Amino Acid|Vertebrate|Ion Transport|SLC22A23 protein, human|Organic Anion Transporters" 11 TYRL 17355913 Prog Retin Eye Res 2007 10.1016/j.preteyeres.2007.01.001 20 8 0 0 "Humans|Oculocutaneous albinism type 1|*Monophenol Monooxygenase|*Albinism, Oculocutaneous|Mutation|TYRP1 protein, human|Oxidoreductases|Exons|*Eye|*Databases, Genetic|Membrane Glycoproteins|Melanocytes|Melanins|copper-binding protein|Carrier Proteins" 11 36951 17090533 J. Biol. Chem. 2006 10.1074/jbc.M606769200 9 0 0 0 "*DNA Adducts|*Temperature|Kinetics|*DNA-Directed DNA Polymerase|*Nucleotides|Benzo(a)pyrene|2'-deoxycytidine 5'-triphosphate|Deoxycytosine Nucleotides|Sulfolobus solfataricus|Models, Molecular|Base Pairing|Guanine|Molecular Conformation|Binding Sites|DNA|Carcinogens, Environmental" 11 DPRX 17005330 Gene 2006 10.1016/j.gene.2006.07.034 20 0 3 4 "Humans|*Genes, Homeobox|Pseudogenes|Amino Acid Sequence|*Germ Line|Proteins, Homeo Domain|Genetic Evolution|Genome, Human|Transcription Factors|Transcription, Genetic" 11 DUSP18 16720344 Front. 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Methods 2006 PMC2431127 10.1016/j.jim.2006.02.013 0 0 0 15 "Humans|*Immune Sera|Immunoglobulin Idiotypes|*B Cell Lymphoma|Cancer Vaccines|Antigens, Neoplasm|Antibodies, Neoplasm|Follicular Lymphoma|*Cell Surface Display Techniques|Epitopes|Amino Acid Sequence|*Antitoxins|T-Lymphocytes|cDNA Library|Phage" 11 HHATL 16778592 Diagn. Mol. Pathol. 2006 10.1097/00019606-200606000-00008 0 0 0 15 "In Situ Hybridization, Fluorescence|Nasopharyngeal Neoplasms|Lymphoma, Large B-Cell, Diffuse|*Cell Nucleus|Oligonucleotide Array Sequence Analysis|Paraffin Embedding|mRNA|Gene Expression Profiling|Gene Expression Regulation, Neoplastic" 11 HHATL 16552956 Ai Zheng 2006 2 0 0 15 "*Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Oligonucleotide Array Sequence Analysis|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Cell Line, Tumor|*Gene Expression" 11 IGSF6 16837177 Colloids Surf B Biointerfaces 2006 10.1016/j.colsurfb.2006.05.021 0 0 0 88 "Mice|Animals|Humans|Amino Acid Sequence|Northern Blot|In Situ Hybridization|Sequence Alignment|Base Sequence|*Embryonic Development|DNA, Complementary|Chromosome Mapping|Cloning, Molecular|Embryo, Mammalian|Gene Expression Regulation, Developmental|RNA, Messenger|Sequence Homology, Amino Acid|RNA|Immunoglobulin|Cell Line|Sequence Analysis, DNA" 11 MTG2 17054726 Genes Cells 2006 10.1111/j.1365-2443.2006.01017.x 13 0 0 47 Humans|HeLa Cells|Escherichia coli|Escherichia coli Proteins|Small G-Proteins|*Mitochondria|Bacterial Proteins|Ribosome|small protein B|*RNA-Binding Proteins|Amino Acid Sequence 11 SFSWAP 16738036 Thorax 2006 PMC2104763 10.1136/thx.2005.055475 6 0 1 225 *Genetic Linkage|*Asthma|Chromosome Mapping|Genetic Predisposition to Disease|Microsatellite Repeats|Genotype|*Chromosome Structures 11 SHROOM4 17009331 Cell Motil. Cytoskeleton 2006 10.1002/cm.20167 13 3 0 42 "Humans|Mice|Animals|*Actins|Endothelial Cells|Cytoskeleton|Microfilament Proteins|Actin Cytoskeleton|Myosin II|Cytoskeletal Proteins|Fibroblasts|Cytoplasm|Cell Line|*Cell Physiological Phenomena|Embryo, Mammalian|Vertebrate|Endothelium, Vascular" 11 SLAIN2 16546155 Dev. Biol. 2006 10.1016/j.ydbio.2006.01.023 23 0 1 169 "Mice|Humans|Animals|*Human Embryonic Stem Cells|*Stem Cell|Cell Differentiation|Embryo, Mammalian|Epiblast|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Developmental|Mesoderm|Cell Line|Gene Expression|SLAIN2 protein, human|Microtubule-Associated Proteins" 11 SPATA17 16395525 Acta Biochim. Biophys. Sin. 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Chem. 2006 10.1074/jbc.M610590200 32 0 1 51 "Mice|Animals|endopeptidase B|*Cysteine Endopeptidases|tripeptide aminopeptidase|Ufm1 protein, mouse|Sequences, Amino Acid|*Aminopeptidases|Ubiquitin-Like Proteins|SUMO-1 Protein|Ubiquitin|Substrate Specificity" 11 CEACAM16 16139472 Genomics 2005 10.1016/j.ygeno.2005.07.008 42 0 0 3 "Humans|Mice|Rats|Female|Pregnancy|Animals|CEACAM5 protein, human|*Carcinoembryonic Antigen|Genome-Wide Association Study|CD66 antigens|Cell Adhesion Molecules|*Biological Evolution|Amino Acid Sequence|*GPI-Linked Proteins|Base Sequence|Antigens, CD|Exons|Genome|Phylogeny|Sequence Homology, Amino Acid|DNA, Complementary|Gene Expression Profiling|ceacam16 protein, human|CEACAM20 protein, human" 11 DPRX 16200348 J. Biomed. Sci. 2005 10.1007/s11373-005-9013-2 3 2 0 4 Animals|*5' Untranslated Regions|*Drosophila|*Peroxiredoxin I|Alternative Splicing|Base Sequence|Protein Biosynthesis|*Heat-Shock Proteins|Isoforms|Open Reading Frames 11 HHATL 16234092 Di Yi Jun Yi Da Xue Xue Bao 2005 1 0 0 15 "Humans|*Transfections|Cell Line, Tumor|Genetic Vectors|Genes, Tumor Suppressor|Neoplasm Transplantation|Cloning, Molecular" 11 LYZL4 16014814 Biol. Reprod. 2005 10.1095/biolreprod.105.041889 16 0 2 5 "Male|Animals|Humans|*Lactalbumin|lysozyme C, human|*Muramidase|*Cloning, Molecular|Sequences, Amino Acid|*Male Reproductive System|Spermatozoa|Northern Blot|cDNA|Bacteriolysis|Phylogeny|mRNA|In Situ Hybridization|LYZL4 protein, human|LYZL6 protein, human" 11 MAATS1 15863901 Biol. Pharm. Bull. 2005 10.1248/bpb.28.898 2 0 0 14 "Humans|Male|*Isoforms|Binding Protein|DNA-Binding Proteins|Transcription Factors|Amino Acid Sequence|Base Sequence|Spermatogenesis|Promoter Regions, Genetic|RNA Splicing|Exons|Testis|RNA, Messenger|Mitochondria|Sequence Homology, Amino Acid" 11 TYRL 15895460 Hum. Mutat. 2005 10.1002/humu.20171 10 0 0 0 "*Monophenol Monooxygenase|Oculocutaneous albinism type 1|Albinism, Oculocutaneous|DNA Mutational Analysis|Exon|Mutations|DNA Primers|PCR|*Chromosome Structures|SNPs" 11 36951 15210693 J. Biol. Chem. 2004 10.1074/jbc.M404332200 17 1 0 0 "*DNA Adducts|*Catalytic Domain|Escherichia coli|*DNA Polymerases|*Nucleotides|*Carcinogens|7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide|Benzo(a)pyrene|Mutagenesis|Models, Molecular|Protein Conformation|DNA Replication|Base Pair|Mutagens|Guanine|Nucleic Acid Conformation|DNA Damage|Templates, Genetic" 11 36951 15057460 Curr. Microbiol. 2004 10.1007/s00284-003-4111-8 2 0 0 0 "*Photobacterium|*Porins|Amino Acid Sequence|Bacterial Outer Membrane Proteins|Cloning, Molecular|Base Sequence|DNA, Bacterial|Sequence Homology, Amino Acid|Vibrio|Molecular Weight|Sequence Analysis, DNA|Electrophoresis, Polyacrylamide Gel|Escherichia coli" 11 CDH20 15273735 Oncogene 2004 10.1038/sj.onc.1207675 18 0 2 17 "Animals|Mice|CDH1 protein, human|N-Cadherin|*Embryogenesis|Gene Expression Regulation, Developmental|Amino Acid Sequence|mRNA|In Situ Hybridization|Base Sequence|Cell Adhesion|Brain|Antigens, CD|Neural Crest Cells|Sequence Alignment|DNA, Complementary|*Melanocyte|Sequence Homology, Amino Acid|Cloning, Molecular" 11 CFAP410 15068244 J. Neural Transm. Suppl. 2004 10.1007/978-3-7091-6721-2_10 5 0 1 41 "Humans|Adult|*Down Syndrome|*Chromosomes, Human, Pair 21|*Chromatin Assembly Factor-1|Alzheimer Disease|*Brain|*Proteins|Gene Dosage|Fetus|Frontal Cortex|C21orf2 protein, human" 11 LRP11 15109771 Adv. Drug Deliv. Rev. 2004 10.1016/j.addr.2003.12.003 21 5 4 21 "Animals|Humans|Cricetinae|VLDL receptor|*Low Density Lipoprotein Receptor|LDLR protein, human|low density lipoprotein receptor-related protein 8|LDL-Receptor Related Proteins|SORL1 protein, human|LRP2 protein, human|Megalin|Lipoproteins, LDL|Low Density Lipoprotein Receptor-Related Protein-1|Binding Sites|Protein Binding|Endocytosis|Ligands|*Biological Transport|Carrier Proteins|Lipoproteins|CHO Cells" 11 MTG2 15591131 Mol. Biol. Cell 2004 PMC545925 10.1091/mbc.e04-07-0622 26 1 1 47 "*Saccharomyces cerevisiae|*GTPases|21S rRNA|RNA, Ribosomal|*Protein Biosynthesis|Ribosomes|Saccharomyces cerevisiae Proteins|rRNA (adenosine-O-2'-)methyltransferase|*Methyltransferases|Ribosomal Proteins|DNA, Mitochondrial|*Yeast, Dried|Mitochondria|Mitochondrial Proteins|RNA Processing, Post-Transcriptional|Mitochondrial Membranes|Mitochondrial Ribosomes" 11 NBEAL1 15193433 Brain Res. Mol. Brain Res. 2004 10.1016/j.molbrainres.2004.02.022 11 0 0 21 "Male|Female|Humans|*Protein A|*Glioma|*Transcriptional Activation|Brain Neoplasms|Base Sequence|*Up-Regulation|Amino Acid Sequence|Exons|cDNA|Northern Blot|Nerve Tissue Proteins|Cloning, Molecular|Gene Expression Regulation, Neoplastic|Brain" 11 SFSWAP 15009664 J. Neurochem. 2004 10.1046/j.1471-4159.2003.02232.x 34 0 2 225 "Animals|Humans|Chlorocebus aethiops|Adult|*Frontotemporal Dementia|*Exon|*Pick Disease of the Brain|RNA Splicing|Splicings, Alternative|tau Proteins|Introns|Mutations|COS Cells|Protein Binding|Nervous System" 11 ANKAR 12769171 Folia Morphol. 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Acta 2003 10.1016/s0167-4781(02)00629-2 3 4 0 121 "Humans|*Cloning, Molecular|Tyrosine Phosphatases, Protein|Phosphoprotein Phosphatases|cDNA Library|cDNA|Base Sequence|Dual-Specificity Phosphatases|Amino Acid Sequence|Signal Transduction|Substrate Specificity|Phosphorylation|nitrophenylphosphate|Organophosphorus Compounds|*Specificity|4-aminophenylphosphate|Aniline Compounds|Nitrophenols|Brain" 11 IGSF6 12786995 Eur. J. Immunogenet. 2003 10.1046/j.1365-2370.2003.00387.x 2 0 0 88 "Humans|*Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn Disease|Linkage Disequilibrium|Single Nucleotide Polymorphisms|Nod2 Signaling Adaptor Protein|Genetic Predisposition to Disease|Gene Frequency|Genotype|Haplotypes|*DNA Mutational Analysis|Chromosome Mapping|Exons|*Immunoglobulin Gene|Carrier Proteins|Cohort Studies" 11 SPATA6 12771232 Mol. Hum. Reprod. 2003 10.1093/molehr/gag047 8 0 0 55 "Humans|Male|Female|Mice|Rats|Animals|*Spermatogenesis|Testis|Spermatids|Spermatogonia|Amino Acid Sequence|Base Sequence|In Situ Hybridization|Exons|mRNA|Spermatocytes|Transcription Factors|Introns|Ovary|Organ Specificity|Embryo, Mammalian|SPATA6 protein, human|Cytoskeletal Proteins" 11 ANKAR 11905246 Folia Morphol. (Warsz) 2002 0 0 0 1 Guinea Pigs|Animals|*Nerve Cells|*Mammillary Bodies|Nissl Bodies|*Golgi Apparatus|Silver Staining|Axons|Cell Size|Mammillary Region 11 DUSP18 12408986 Biochem. Biophys. Res. Commun. 2002 10.1016/s0006-291x(02)02488-9 5 12 0 121 "Humans|Male|Animals|Chlorocebus aethiops|*Dual-Specificity Phosphatases|*Molecular Weight|Mitogen-Activated Protein Kinase Phosphatases|COS Cells|Protein Tyrosine Phosphatases|Mitogen-Activated Protein Kinases|Amino Acid Sequence|Transfection|Cytoplasm|Base Sequence|JNK Mitogen-Activated Protein Kinases|MAP Kinase Signaling System|Blotting, Northern|Phosphorylation|Substrate Specificity|DNA, Complementary|p38 Mitogen-Activated Protein Kinases|Cloning, Molecular" 11 MAATS1 12223483 J. Biol. Chem. 2002 10.1074/jbc.M206201200 10 4 2 14 Humans|Rats|Male|Mice|Animals|*cAMP Dependent Protein Kinase|*A Kinase Anchor Proteins|*Phosphorylation|*Testis|HeLa Cells|Spermatogenesis|DNA-Binding Proteins|Sperm|Membrane Proteins|Spermatid|Alternative Splicing|Amino Acid Sequence|Mitochondria|Protein Binding|Binding Sites|Cyclic AMP-Dependent Protein Kinase Type II 11 SFSWAP 12077342 Mol. Cell. Biol. 2002 PMC139773 10.1128/mcb.22.14.5141-5156.2002 35 2 1 225 "Animals|*Ribonucleoprotein, U5 Small Nuclear|*Spliceosomes|Ribonucleoprotein, U4-U6 Small Nuclear|Schizosaccharomyces pombe|RNA Splicing|Schizosaccharomyces pombe Proteins|RNA Splicing Factors|Saccharomyces cerevisiae Proteins|RNA Precursors|Amino Acid Sequence|NCOR1 protein, human|*Nuclear Receptor Co-Repressor 1|Protein-Serine-Threonine Kinases|*Mammals|Co-Immunoprecipitation|Sequence Homology, Amino Acid|prp4 protein, S pombe" 11 36951 11483601 J. Biol. 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Commun. 2001 10.1006/bbrc.2001.6048 2 0 0 55 "Male|Rats|Animals|*Testis|*Spermatogenesis|Amino Acid Sequence|OF-1 protein|*DNA-Binding Proteins|DNA, Complementary|Base Sequence|In Situ Hybridization|Meiosis|Cloning, Molecular|Sequence Homology, Amino Acid|RNA, Messenger|Germ Cells|Gene Expression Regulation, Developmental" 11 TYRL 11732911 Biochemistry 2001 10.1021/bi011174b 0 0 0 0 "Mice|Animals|*Oestradiol|*Site, Combining|*Photoaffinity Labels|Binding Sites, Antibody|Base Sequence|Amino Acid Sequence|Immunoglobulin Heavy Chains|*Estrogens|*Steroids|Immunoglobulin Light Chains|Models, Molecular|Cross Reactions|Antibodies, Monoclonal|Haptens" 11 CDH20 10995570 Genomics 2000 10.1006/geno.2000.6305 6 0 0 17 "Humans|Mice|Animals|*Chickens|Phylogeny|*Chromosome|*Cadherins|Base Sequence|Chromosome Mapping|Exons|Cloning, Molecular|Amino Acid Sequence|Genome, Human|Sequence Homology, Amino Acid|Multigene Family" 11 IGSF6 11132146 Immunogenetics 2000 10.1007/s002510000259 2 0 0 88 "Mice|Humans|Rats|Animals|*Introns|*Crohn Disease|Exons|cDNA|Base Sequence|Cloning, Molecular|Amino Acid Sequence|Chromosome Mapping|Northern Blot|DNA|mRNA|Cosmid|Sequence Homology, Amino Acid" 11 ANKAR 10456980 Anat. 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Immunol. 1998 10.1016/s0161-5890(98)00045-5 4 2 2 88 "Humans|Rats|Animals|*CD40 Ligand|*Immunoglobulin|Monocytes|cDNA|Dendritic Cells|Amino Acid Sequence|*Downregulation|Cloning, Molecular|Base Sequence|B Cells|Spleen|Sequence Homology, Amino Acid|Germinal Centers|mRNA|Blotting, Northern" 11 SFSWAP 8940107 J. Biol. Chem. 1996 10.1074/jbc.271.49.31106 14 0 1 225 "Humans|Mice|Animals|*Alternative Splicing|*mRNA|*Prunus armeniaca|FN1 protein, human|*Fibronectins|*RNA Splicing|*Exon|RNA Precursors|Serine-Arginine Splicing Factors|Splicing Factors|Intron|RNA-Binding Proteins|PTPRC protein, human|*Leukocyte Common Antigens|Splice Site, 5'|*Mammals|Nuclear Proteins|Base Sequence" 11 SFSWAP 8206918 J. Biol. 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Behav. 1983 2 0 0 0 "Male|Animals|Rats|*Endorphins|*Psychological Distress|beta LPH|beta-Endorphin|gamma-Endorphin|alpha-Endorphin|Rats, Inbred Strains|*Heart" 11 AP5Z1 32641631 Rinsho Shinkeigaku 2020 10.5692/clinicalneurol.60.cn-001419 0 0 0 46 "Male|Female|Humans|Aged|Middle Aged|Spastic paraplegia 11, autosomal recessive|Spastic Paraplegias, Hereditary|Spastic paraplegia 15, autosomal recessive|Proteins|Mutations|Genes, Recessive|Corpus Callosum|Retinal Degeneration|Carrier Proteins|Heterozygote|Pedigree|Exon|Magnetic Resonance Imaging|Genetic Heterogeneity|Mutation, Frame Shift|Paraplegia|SPG11 protein, human|spastizin protein, human" 10 AVL9 32678693 Per Med 2020 10.2217/pme-2019-0108 0 0 0 130 10 AVL9 32038723 Front Genet 2020 PMC6993758 10.3389/fgene.2019.01385 0 0 0 130 "Humans|*Colorectal Cancer|*Tumorigenesis|*Colonic Neoplasms|MicroRNAs|RNA, Long Noncoding|*Cell Transformation, Neoplastic|*Disease Progression|Gene Expression Regulation, Neoplastic|HCT116 Cells|Cell Proliferation|Cell Movement|3' Untranslated Regions|Cell Line, Tumor|MIRN497 microRNA, human" 10 CEP128 31960101 Exp Brain Res 2020 10.1007/s00221-020-05730-0 0 0 0 311 "Humans|COMT protein, human|*Catechol O-Methyltransferase|*Genotypes|*Dorsolateral Prefrontal Cortex|SNPs|*Gene Expression|Cognition" 10 CLCC1 32316189 Cells 2020 PMC7226988 10.3390/cells9040986 0 0 0 118 "sodium-bile acid cotransporter|Organic Anion Transporters, Sodium-Dependent|Symporters|Taurocholate|Hepatocytes|Bile Acids and Salts|Biological Transport|Hepatitis B|*Sodium|Liver|HepG2 Cells|Plasma Membrane|*Membrane Microdomains" 10 CLCC1 31953506 Sci Rep 2020 PMC6969029 10.1038/s41598-019-57358-y 0 0 0 118 "Humans|*Analgesics, Opioid|*Nausea|*Vomiting|Antiemetics|SNPs|Cancer Pain|*Neoplasms|Allele|Pharmacogenetic Study" 10 CPXM1 32078680 Blood Adv 2020 PMC7042996 10.1182/bloodadvances.2019001185 0 0 0 24 "Humans|*Myelodysplastic Syndrome|*Prognosis|Leukemia, Myeloid, Acute|Risk Factor|Disease-Free Survival|Kaplan-Meier Estimate|Retrospective Studies|Relapse|Mutations|Genes, Regulator|Stem Cells|LAPTM4B protein, human|Membrane Proteins|Oncogene Proteins" 10 DIRAS2 32161311 Oncogene 2020 10.1038/s41388-020-1247-y 0 0 0 36 "Humans|*Carcinoma, Renal Cell|VHL protein, human|Von Hippel-Lindau Tumor Suppressor Protein|Kidney Neoplasms|*Mitogen-Activated Protein Kinases|Ubiquitination|Phosphorylation|Signal Transduction" 10 DNAH6 32582379 Mol Cytogenet 2020 PMC7310204 10.1186/s13039-020-00495-1 0 0 0 8 "Humans|Male|Acrosome|Infertility, Male|Sperm Head|Globozoospermia|Spermatozoa|Homozygote|Gene Deletion|Point Mutation|Membrane Proteins" 10 EMC4 32661467 Int J Clin Exp Pathol 2020 PMC7344010 0 0 0 30 "*miRNAs|*mRNA|*Stomach Neoplasms|*Thy-1 Antigens|*Cancer Stem Cell|CD44 protein, human|*Hyaluronan Receptors|Gene Expression Regulation, Neoplastic|Downregulation|Up-Regulation|Gene Regulatory Networks|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Cell Line, Tumor|*Stomach|Gene Ontology|Signal Transduction" 10 EMC4 32494008 Nature 2020 10.1038/s41586-020-2389-3 0 0 0 30 "*Endoplasmic Reticulum|SEC61 Translocon|Intracellular Membranes|Integral Membrane Proteins|*Protein Domains|Protein Transport|Protein Processing, Post-Translational" 10 EMC4 32476094 J Genet Eng Biotechnol 2020 PMC7261713 10.1186/s43141-020-00029-7 0 0 0 30 Humans|*Eukaryotic Initiation Factor-2B|*Saccharomyces cerevisiae|*Eukaryotic Initiation Factor-2|Saccharomyces cerevisiae Proteins|Amino Acid Sequence|Guanine Nucleotide Exchange Factors|Mutation|Repressor Proteins|Leukoencephalopathy|Membrane Proteins 10 EMC4 32111841 Nat Commun 2020 PMC7048770 10.1038/s41467-020-14967-w 0 0 0 30 Chlorocebus aethiops|Humans|Animals|*Endoplasmic Reticulum|Intracellular Membranes|Simian virus 40|*Virus Entry|Cytosol|Endosomes|Protein Transport|Membrane Proteins|Polyomavirus Infections|HEK293 Cells|Gene Knockdown Techniques|Biological Transport|COS Cells 10 FAM208A 32345670 Cancer Genomics Proteomics 2020 PMC7259889 10.21873/cgp.20189 0 0 0 126 Humans|*Sequence Analysis|Colorectal Cancer|Exome|Germ-Line Mutation|Genetic Predisposition to Disease|Precision Medicine|*Rectal Neoplasms|Colonic Neoplasms|Adenocarcinoma|*Germ Line 10 GPR153 32643557 Nucleosides Nucleotides Nucleic Acids 2020 10.1080/15257770.2020.1780437 0 0 0 12 "Male|Animals|Rats|*Diabetic Nephropathies|*Rats, Wistar|Diabetes Mellitus, Experimental|Kidney|Streptozotocine|Proteinuria|Oxidative Stress" 10 GPR153 32249236 J. 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Anal. 2020 10.1002/jcla.23450 0 0 0 16 "*Lung Adenocarcinoma|*Prognosis|Gene Regulatory Networks|Gene Ontology|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Databases, Genetic|Computational Biology|Biomarkers, Tumor|Lung Neoplasms" 10 PKHD1L1 32555200 Sci Data 2020 PMC7299942 10.1038/s41597-020-0509-4 0 0 0 16 "Mice|Animals|*Stereocilia|*Microscopy, Electron, Scanning|*Gold|Hair Cells, Auditory, Inner|Hair Cells, Auditory, Outer|Hearing|Cilia" 10 PPP1R14B 32021296 Onco Targets Ther 2020 PMC6974148 10.2147/OTT.S221276 0 0 0 139 "Humans|Male|*Messenger RNA|*Prostate|*Computational Biology|Prostate Cancer|Antigens, Neoplasm|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic" 10 PRR12 32597225 Autoimmunity 2020 10.1080/08916934.2020.1786068 0 0 0 49 "Child|Humans|Blau syndrome|*Whole Exome Sequencing|*Familial Mediterranean Fever|*Synovitis|*Arthritis|*Uveitis|Sarcoidosis, Early-Onset|Sarcoidosis|Nod2 Signaling Adaptor Protein|Mutation|Skin Rash|Syndrome" 10 pyroxd1 32037607 Neuropathology 2020 PMC7317439 10.1111/neup.12641 0 0 0 19 "Humans|*Homozygote|Genes, Recessive|*Myopathy|Pedigree|*Base Sequence|Mutation, Missense|*Chromosome Mapping|Mutation|RNA Splicing|Phenotype" 10 RALGAPA1 32004447 Am. 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Genet. 2020 PMC7010976 10.1016/j.ajhg.2020.01.002 0 0 0 46 "Humans|*Spasms, Infantile|*Muscle Hypotonia|*Alleles|Intellectual Disability|RALA protein, human|ral GTP-Binding Proteins|Phenotype|Neurodevelopmental Disorders|Pedigree|Mutation|Cell Signaling|Corpus Callosum" 10 SIPA1L3 32164487 Epigenetics 2020 10.1080/15592294.2020.1741757 0 0 0 52 "Humans|*Papillomavirus Infections|*Alternative Splicing|*Oropharyngeal Neoplasms|*Human Papilloma Virus|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Cancer|Carcinoma, Squamous Cell|*Mouth Neoplasms|Cell Line, Tumor|Case-Control Studies|Chromatin|Humans|*Papillomavirus Infections|*Alternative Splicing|*Oropharyngeal Neoplasms|*Human Papilloma Virus|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Cancer|Carcinoma, Squamous Cell|*Mouth Neoplasms|Cell Line, Tumor|Case-Control Studies|Chromatin" 10 SLC35D3 32087688 BMC Genet. 2020 PMC7036214 10.1186/s12863-020-0822-0 0 0 0 7 "Swine|Animals|*Cell Differentiation|Adipocytes|Adipogenesis|*Cloning, Molecular|Lipid Metabolism|Cells, Cultured|Muscle, Skeletal|Cell Proliferation|Adiposity" 10 SLC35D3 32049988 PLoS ONE 2020 PMC7015415 10.1371/journal.pone.0229007 0 0 0 7 "Humans|*mRNA|*Colorectal Cancer|*Lymph Node|*Colonic Neoplasms|Keratin-20|Lymphatic Metastasis|Prognosis|Biomarkers, Tumor" 10 SLX4IP 32071280 Life Sci Alliance 2020 PMC7032570 10.26508/lsa.201900427 0 0 0 57 "Humans|*Telomere|Neoplasm Recurrence, Local|Telomere Lengthening|Telomerase" 10 SLX4IP 31889939 Clin Proteomics 2020 PMC6921584 10.1186/s12014-019-9263-z 1 0 0 57 "*Carcinoma, Merkel Cell|*Proteome|Merkel cell polyomavirus|*Merkel Cells|Polyomavirus Infections|Skin Neoplasms|Cell Line, Tumor" 10 TAPT1 32242051 Leukemia 2020 10.1038/s41375-020-0808-y 0 0 0 15 "Humans|Infant|Child|Myeloid-Lymphoid Leukemia Protein|*Promoter Regions, Genetic|Oncogene Proteins, Fusion|Histone-Lysine N-Methyltransferase|Gene Expression Regulation, Leukemic|*Cancer Stem Cell|Leukemia|Enhancer Elements, Genetic|Methylation|Histones|Prominin 1|Cell Line, Tumor|MLL-AF4 fusion protein, human|PROM1 protein, human" 10 TAPT1 31912669 J Gynecol Oncol 2020 PMC7044014 10.3802/jgo.2020.31.e11 0 0 0 15 "Humans|Female|*Prognosis|*Endometrial Cancer|Carcinoma, Endometrioid|Endometrium|Biomarkers, Tumor" 10 TMTC1 32572876 Eur Rev Med Pharmacol Sci 2020 10.26355/eurrev_202006_21506 0 0 0 95 "*Carcinoma, Squamous Cell|*Mouth Neoplasms|*RNA, Circular|*Endoplasmic Reticulum Stress|Cell Proliferation|Cell Line, Tumor|MicroRNAs|Gene Expression Regulation, Neoplastic|Apoptosis|*Genes, Tumor Suppressor" 10 TMTC1 32377000 Mol. 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Rep. 2019 PMC6489015 10.3892/or.2019.7108 4 7 0 0 "Humans|Female|*Support Vector Machine|Neoplasm Recurrence, Local|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|miRNA|Gene Expression Regulation, Neoplastic|Prognosis|Gene Regulatory Networks|Databases, Genetic|Gene Expression Profiling|MIRN211 microRNA, human|MIRN218 microRNA, human" 10 MIR505 30628663 Int. J. Mol. Med. 2019 PMC6365022 10.3892/ijmm.2018.4041 5 2 0 0 "Humans|*Carcinoma, Non-Small-Cell Lung|Lung Cancer|*Cell Proliferation|MicroRNAs|*Cell Cycle|Epithelial-Mesenchymal Transition|Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|MAP3K3 protein, human|*MAP Kinase Kinase Kinase 3|Cell Movement|Downregulation|Cell Line, Tumor|Proto-Oncogene Proteins c-akt|3' Untranslated Region|Signal Transduction|Carcinogenesis|Apoptosis" 10 MSTO1 31604776 Cold Spring Harb Mol Case Stud 2019 PMC6913144 10.1101/mcs.a004309 0 0 0 32 "Disorders, Mitochondrial|Mitochondrial Fusion|Pedigree|Mutation|Mitochondria" 10 MSTO1 31463572 Acta Neuropathol. 2019 PMC6851037 10.1007/s00401-019-02059-z 0 0 0 32 "Humans|Child|Mitochondrial Diseases|DNA, Mitochondrial|*Mutations|Mitochondrial Fusion|*Dystrophy, Muscular|Protein, Mitochondrial|Mitochondria|*Cerebellum|Retinopathy, Pigmentary|*Metabolism, Inborn Errors|Phenotype|Alleles|MSTO1 protein, human|Cytoskeletal Proteins|Cell Cycle Proteins" 10 MSTO1 31130378 Neuromuscul. Disord. 2019 10.1016/j.nmd.2019.03.011 1 1 0 32 "Humans|*Dystrophy, Muscular|Cerebellar Ataxia|Phenotype|Myopathy|Sequencing, Whole Exome|Mutations|Retinopathy, Pigmentary|Pedigree|Cytoskeletal Proteins|Cerebellum|Magnetic Resonance Imaging|Mutation, Missense|MSTO1 protein, human|Cell Cycle Proteins" 10 MSTO1 30684668 Eur J Med Genet 2019 10.1016/j.ejmg.2019.01.013 2 0 0 32 "Humans|Male|*Cerebellar Ataxia|*Whole Exome Sequencing|*Mutations|*Myopathy|Ataxia|Exome|Pedigree|Cerebellar Diseases|Retinopathy, Pigmentary|Phenotype|Missense Mutation|Genotype-Phenotype Correlation|Cell Cycle Proteins|Intellectual Disability|MSTO1 protein, human|Cytoskeletal Proteins" 10 MYZAP 31384490 Dermatol Pract Concept 2019 PMC6659599 10.5826/dpc.0903a02 0 0 0 54 Humans|Pemphigus and fogo selvagem|*Compositae|*Pemphigus|Autoantibodies|*Heart|Skin|Desmoplakins|Endemic Diseases|Myocardium|Immunohistochemistry|Antigens|Colombia|South America 10 PKHD1L1 31452800 Oncol Lett 2019 PMC6676403 10.3892/ol.2019.10632 0 0 0 16 "Humans|*Thyroid Gland|*Polycystic Kidney, Autosomal Recessive|*Thyroid Cancer|Thyroid Cancer, Papillary|Carcinoma, Papillary|Lymphatic Metastasis|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Neoplastic Processes|Cell Movement|Cell Line, Tumor|*Disease Progression|*Genes, Tumor Suppressor|Downregulation|Transcriptome|Sequencing, Next-Generation|Cohort Studies" 10 PKHD1L1 31447598 Clin Med Insights Oncol 2019 PMC6689917 10.1177/1179554919868482 1 0 0 16 "Humans|*Triple Negative Breast Neoplasms|*Mutation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic" 10 PKHD1L1 31444330 Nat Commun 2019 PMC6707252 10.1038/s41467-019-11712-w 1 0 0 16 "Mice|Animals|*Stereocilia|*Capsid Proteins|Hair Cells, Auditory, Inner|Hair Cells, Auditory|Hearing Loss|Cochlea|*Hearing Tests|Potter Type III Polycystic Kidney Disease|*Polycystic Kidney Diseases|Scanning Electron Microscopy" 10 PPP1R14B 31827514 J Oncol 2019 PMC6885206 10.1155/2019/9453539 0 0 0 139 "Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|*Transcriptome|Prognosis" 10 PPP1R14B 31151297 Int J Mol Sci 2019 PMC6600271 10.3390/ijms20112672 1 2 0 139 "Mice|Animals|*Mesenchymal Stem Cells|Tandem Mass Spectrometry|*Mice, Inbred C57BL|Cell Differentiation|Adipose Tissue|Cells, Cultured|Flow Cytometry|Biomarkers|Chromatography, Liquid|Syncrip protein, mouse|Heterogeneous-Nuclear Ribonucleoproteins|RPL22 protein, mouse|Ribosomal Proteins|RNA-Binding Proteins|Myo1e protein, mouse|Myosins|SEC61A1 protein, mouse|SEC Translocation Channels" 10 PRR12 31884342 Biomed. Pharmacother. 2019 10.1016/j.biopha.2019.109759 0 0 0 49 "Humans|*Glioma|*Tumorigenesis|lncRNA|*Cell Transformation, Neoplastic|Cell Proliferation|*Genes, Tumor Suppressor|Glioblastoma|MicroRNAs|Gene Expression Regulation, Neoplastic|Brain Neoplasms|Cell Movement|Cell Line, Tumor|Upregulation|Downregulation|RAD21 protein, human|Nuclear Proteins|Phosphoproteins" 10 pyroxd1 31859631 Med Sci (Paris) 2019 10.1051/medsci/2019183 0 0 0 19 10 pyroxd1 31502705 J. Cell. 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Cell 2019 PMC6863466 10.1016/j.molcel.2019.07.010 7 4 0 57 "Humans|*Telomere Lengthening|Telomere|RecQ Helicases|DNA Replication|Telomerase|Recombinases|HeLa Cells|Cell Cycle|Cell Line, Tumor" 10 SLX4IP 31270560 Mamm. Genome 2019 PMC6836689 10.1007/s00335-019-09809-0 1 0 0 57 "Humans|Mice|Animals|Child|*Precision Medicine|*Genome|Genomics|Computational Biology|Phenotype|Genome-Wide Association Study|Proteins|Drug Discovery|LRRC10 protein, human|Microfilament Proteins" 10 SLX4IP 30979813 Mol. Pharmacol. 2019 10.1124/mol.118.115196 1 1 0 57 "TH 302|*RNA, Small Interfering|*Clustered Regularly Interspaced Short Palindromic Repeats|*Electron Transport|*Phosphoramide Mustards|*Nitroimidazoles|Prodrugs|Xenograft Model Antitumor Assays|Cell Line, Tumor|Cell Hypoxia|Cell Survival" 10 TAPT1 31234802 BMC Genomics 2019 PMC6591854 10.1186/s12864-019-5889-5 1 0 0 15 "Swine|Animals|Quantitative Trait Loci|*Muscle, Skeletal|Genotype|Transcriptomes|Genome-Wide Association Study|Phenotype|mRNA|Polymorphism, Single Nucleotide|*Liver|DNA Copy Number Variations" 10 TAPT1 30669987 BMC Genomics 2019 PMC6341744 10.1186/s12864-019-5450-6 4 0 0 15 "*Mycobacterium tuberculosis Infection|Mycobacterium tuberculosis|*Macrophage|Gene Expression Regulation|*Regulatory Sequences, Nucleic Acid|Cell Line" 10 TMEM207 31699801 Biol Open 2019 PMC6899036 10.1242/bio.044438 0 0 0 20 "Mice|Animals|*Transgenic Mouse|*Mice, Inbred C57BL|*Disease Models, Animal|TFF3 protein, human|Intestinal Trefoil Factor|*Myeloproliferative Disorders|Membrane Proteins|Carrier Proteins|Trefoil Factor-2|Promoter Regions, Genetic|Muscle Proteins|*Phenotype|Stomach Neoplasms|Mucins|TMEM207 protein, mouse" 10 TMTC1 31852448 BMC Genet. 2019 PMC6921553 10.1186/s12863-019-0797-x 0 0 0 95 "Humans|*Genome-Wide Association Study|*Obesity, Morbid|*Asian Continental Ancestry Group|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genotype|Body Mass Index|Case-Control Studies|Proteins|Gain, Weight|Risk Factors|Asia" 10 TMTC1 31851597 Mol. Biol. Cell 2019 PMC7001481 10.1091/mbc.E19-07-0408 0 0 0 95 "*Cell Adhesion|*Glycosylation|*Gastrulation|CDH1 protein, human|*E Cadherin|*Antigens, CD|TYRP1 protein, human|*Membrane Glycoproteins|Cell Adhesion Molecules|*Endoplasmic Reticulum|Mannose" 10 TMTC1 31592238 Int. J. Biol. Sci. 2019 PMC6775300 10.7150/ijbs.36412 3 5 0 95 10 TMTC1 30999272 Curr. Opin. Struct. 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Genet. 2018 PMC6031053 10.1093/hmg/ddy156 8 4 0 46 "Humans|Spastic paraplegia 15, autosomal recessive|*Spastic Paraplegia, Hereditary|*Mitochondrial Dynamics|*Axons|GTPase|Mitochondria|Retinal Degeneration|Mitochondrial Proteins|Neurons|Mutations|Phenotype|Adenosine Triphosphatases|Membrane Potential, Mitochondrial|spastizin protein, human|Carrier Proteins" 10 AP5Z1 29381698 PLoS Biol. 2018 PMC5806898 10.1371/journal.pbio.2004411 16 15 0 46 "Humans|HeLa Cells|*Endosome|*Golgi Apparatus|Spastic paraplegia 11, autosomal recessive|Hereditary Spastic Paraplegia|sortilin|Adaptor Proteins, Vesicular Transport|Protein Transport|Spastic paraplegia 15, autosomal recessive|Lysosome|IGF2R protein, human|Receptor, IGF Type 2|Sorting Nexins|Vesicular Transport Proteins|Carrier Proteins|Retinal Degeneration|GOLM1 protein, human|Membrane Proteins" 10 APOLD1 30086735 BMC Med Genomics 2018 PMC6081936 10.1186/s12920-018-0379-1 7 2 0 51 Humans|*Gastroparesis|*Transcriptome|*Diabetes Mellitus|Gastric Emptying|Stomach|Interstitial Cells of Cajal|Signal Transduction 10 ATP13A3 29650961 Nat Commun 2018 PMC5897357 10.1038/s41467-018-03672-4 52 8 0 63 "*Pulmonary Arterial Hypertension|*Heritable Pulmonary Arterial Hypertension|BMPR2 protein, human|Bone Morphogenetic Protein Receptors, Type II|Mutations|Genetic Predisposition to Disease|Endothelial Cells|Case-Control Studies" 10 AVL9 30122945 Onco Targets Ther 2018 PMC6082348 10.2147/OTT.S169155 3 3 0 130 "Humans|*Carcinoma, Renal Cell|*RNA, Long Noncoding|Kidney Neoplasms|*Cell Migration|Prognosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Line, Tumor|Apoptosis|Neoplasm Staging|Kaplan-Meier Estimate|*Hypoxia" 10 CEP128 30393005 Mol. 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Med. 2018 PMC6069875 10.1186/s10020-018-0039-0 19 2 0 311 "*Urinary Bladder Neoplasms|*RNA, Circular|*Bladder|*SOXC Transcription Factors|MicroRNAs|*Disease Progression|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|*Neoplastic Processes|Cell Line, Tumor|Apoptosis" 10 CEP128 29514088 Cell Rep 2018 10.1016/j.celrep.2018.02.043 9 1 0 311 Animals|Female|Humans|*Centrioles|*Cilia|*Mothers|Centrosome|*Signal Transduction|Basal Body|Proteins|Carrier Proteins|Organelles|*Transforming Growth Factor|Cell Line|Zebrafish|Protein Transport 10 CHIC1 29629573 Cartilage 2018 PMC7097986 10.1177/1947603518764260 2 0 0 60 *Intervertebral Disk|Anulus Fibrosus|Nucleus Pulposus|*Biomarkers|Gene Expression Profiling 10 CHIC1 29316023 Oral Dis 2018 10.1111/odi.12825 5 0 0 60 "Humans|Female|*X Chromosome|DNA Methylation|Epigenesis, Genetic|X Chromosome Inactivation|Salivary Glands|Sjogren's Syndrome|*Epigenetic|Genes, X-Linked|Transcription Factors|Genotype|Gene Expression" 10 CLCC1 30157172 PLoS Genet. 2018 PMC6133373 10.1371/journal.pgen.1007504 6 1 0 118 "Mice|Animals|*Channel, Chloride|*Retinitis Pigmentosa|Retinal Cone Photoreceptor Cells|Retinal Rod Photoreceptor Cells|*Mutation|Retina|Eye Proteins|Homozygote|Zebrafish|*Cytoplasm|Mutant Protein|Mutation, Missense" 10 CNTLN 30487138 Cancer Res. 2018 PMC6359979 10.1158/0008-5472.CAN-17-3864 1 0 0 162 "Humans|Female|Genome-Wide Association Study|Carcinoma, Ovarian Epithelial|SNPs|Genetic Predisposition to Disease|Ovarian Cancer|*Ovary|Genotype|Allele|DNA-Binding Proteins" 10 CPXM1 30072699 Sci Rep 2018 PMC6072708 10.1038/s41598-018-29952-z 3 0 0 24 "*Thyroid Cancer, Papillary|Thyroid Neoplasms|Carcinoma, Papillary|Pedigree|Carcinoma|Genetic Predisposition to Disease|Mutation, Missense|Serine Endopeptidases" 10 DIRAS2 29488099 J Neural Transm (Vienna) 2018 10.1007/s00702-018-1867-3 1 0 0 36 Humans|Female|Pregnancy|Animals|Mice|*Attention Deficit Disorder with Hyperactivity|*C57BL Mice|*Brain 10 DIRAS2 29368982 Autophagy 2018 PMC5959337 10.1080/15548627.2018.1427022 5 8 0 36 "Humans|Female|Mice|Animals|*ras-Related GTPases|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Autophagy|rho GTP-Binding Proteins|Cell Line, Tumor|Downregulation|MAP Kinase Signaling System|*Ovary|*Autophagic Cell Death|Cell Movement|DIRAS3 protein, human|DIRAS1 protein, human|GTP Phosphohydrolases|Tumor Suppressor Proteins" 10 DNAH6 29851510 Am. 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Reprod. 2018 10.1093/humrep/dey264 10 1 0 55 "Humans|Male|*Whole Exome Sequencing|*Sperm Flagellum|Infertility, Male|Spermatozoa|*Mutations|*Multiple Abnormalities|Microtubule Proteins|Cytoskeletal Proteins" 10 GXYLT2 30344988 Hematol Rep 2018 PMC6176398 10.4081/hr.2018.7576 1 13 0 145 "Humans|JAG1 protein, human|Jagged-1 Protein|Notch Receptors|Serrate-Jagged Proteins|Intercellular Signaling Peptides and Proteins|*Glycosyltransferases|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Calcium-Binding Proteins|Leukemia, Myeloid, Acute|Receptor, Notch1|Ligands|Signal Transduction|Recombinant Proteins|Immunoblotting|Cell Line, Tumor|MFNG protein, human|Hexosyltransferases" 10 GXYLT2 29859070 BMC Oral Health 2018 PMC5984765 10.1186/s12903-018-0559-6 0 0 0 145 "Child|Adult|Humans|Dental Caries|Genome-Wide Association Study|Dentition, Permanent|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Phenotype|DMF Index|Genetic Variation|Tooth, Deciduous" 10 LHFPL3 30314994 Biosci. 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Cell 2018 PMC5792066 10.1016/j.devcel.2017.12.003 13 61 0 29 "Humans|Mice|Animals|*Hedgehog Proteins|*Clustered Regularly Interspaced Short Palindromic Repeats|SMO protein, human|Smoothened Receptor|Cilia|Signal Transduction|*Morphogenesis|NIH 3T3 Cells|Cell Movement|Protein Transport|Cell Membrane|HEK293 Cells|MGRN1 protein, human|Ubiquitin-Protein Ligases" 10 MIR505 30146762 J. Cell. Physiol. 2018 10.1002/jcp.27127 10 0 0 0 "Humans|*Circulating MicroRNA|Gene Expression Profiling|Transcriptome|ROC Curve|MicroRNAs|Biomarkers, Tumor|Prognosis|Case-Control Studies|MIRN184 microRNA, human" 10 MSTO1 30361041 Mol. Genet. Metab. 2018 10.1016/j.ymgme.2018.10.003 7 0 0 32 *Mitochondrial Dynamics|Mitophagy|Mitochondria|Mitochondrial Proteins|Apoptosis|Autophagy 10 MSTO1 29339779 J. Hum. Genet. 2018 10.1038/s10038-017-0405-8 3 0 0 32 "Humans|*Retinopathy, Pigmentary|Genes, Recessive|Exome|*Cerebellar Diseases|Pedigree|Mutation|*Retina|Phenotype|Genetic Association Studies|Intellectual Disability|Missense Mutation|Atrophy|MSTO1 protein, human|Cytoskeletal Proteins|Cell Cycle Proteins" 10 MYZAP 30479852 Dermatol Pract Concept 2018 PMC6246068 10.5826/dpc.0804a02 0 0 0 54 Humans|Pemphigus and fogo selvagem|*Pemphigus|Autoantibodies|Skin|Desmoplakins|Endemic Diseases 10 MYZAP 30271950 Commun Biol 2018 PMC6123807 10.1038/s42003-018-0068-9 2 1 0 54 "Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Atrial Fibrillation|Iceland|Norway" 10 MYZAP 29768670 Clin. Exp. Dermatol. 2018 10.1111/ced.13566 1 0 0 54 "Humans|Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|*Desmoplakins|Skin|Endemic Diseases|*Kidney|Immunohistochemistry|Colombia|ARVCF protein, human|Phosphoproteins|Cell Adhesion Molecules|Armadillo Domain Proteins" 10 MYZAP 29445566 Dermatol Pract Concept 2018 PMC5808363 10.5826/dpc.0801a01 1 2 0 54 Humans|Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|Colombia|*Cell Junctions|Desmoplakins|South America|Skin|Endemic Diseases|Immunohistochemistry|*Central Nervous System|Optic Nerve 10 MYZAP 29339073 Gene 2018 PMC6010073 10.1016/j.gene.2018.01.029 1 24 0 54 "Rats|Animals|Humans|Mice|*N-Methylaspartate|*Receptors, N-Methyl-D-Aspartate|*Signal Transduction|Protein Subunits|alpha-internexin|*Intermediate Filament Proteins|Neurons|Hippocampus|Cerebral Cortex|Brain|Protein Binding|Cells, Cultured|Co-Immunoprecipitation|Cell Line|*Ion Transport" 10 PRR12 30573655 Ann. Rheum. Dis. 2018 PMC6800208 10.1136/annrheumdis-2018-214127 7 0 0 49 "Lupus Erythematosus, Systemic|Rheumatoid Arthritis|Genome-Wide Association Study|Sclerosis, Systemic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Rheumatic Diseases|Idiopathic Inflammatory Myopathies" 10 PRR12 29556724 Hum. Genet. 2018 10.1007/s00439-018-1877-0 1 0 0 49 "Child|Humans|Female|*Intellectual Disability|*Eye Abnormalities|*Mutations|Hypotonia|Sequencing, Whole Exome|Heterozygote|Exome|Developmental Disabilities|Phenotype|Haploinsufficiency|Nuclear Protein|Brain|Iris" 10 pyroxd1 30515627 J. Neurol. 2018 PMC6373352 10.1007/s00415-018-9137-8 2 0 0 19 "Adult|Humans|*Muscular Dystrophies, Limb-Girdle|*Mutations|Myofibrillar Myopathy|Myopathies, Structural, Congenital|Exome|Pedigree|Muscle, Skeletal" 10 pyroxd1 30345904 Physiol. Genomics 2018 PMC6293114 10.1152/physiolgenomics.00036.2018 3 0 0 19 "Mice|Animals|Saudi Arabia|Sudan|*Limb Girdle Muscular Dystrophy|*Genetic Testing|Homozygote|Pedigree|Mutation|Phenotype|*Respiration, Cellular" 10 pyroxd1 30203143 J. Appl. Genet. 2018 10.1007/s13353-018-0463-4 2 0 0 19 "Humans|Myofibrillar Myopathy|*Myopathies, Structural, Congenital|Myofibril|*Genomics|Mutations|Phenotype|Adaptor Proteins, Signal Transducing|Muscle, Skeletal|Apoptosis Regulatory Proteins|High-Throughput Nucleotide Sequencing|BAG3 protein, human" 10 pyroxd1 29790964 Gigascience 2018 PMC6007440 10.1093/gigascience/giy058 5 2 0 19 "Swine|Animals|*Genome|Breeding|Selection, Genetic|Sus scrofa|Genotype|Chromosome Mapping|Haplotypes|*Biological Evolution|Sequence Analysis, DNA|Domestication|Phenotype|Genomics|Polymorphism, Single Nucleotide|China" 10 SGSM2 30489189 World J. Biol. Psychiatry 2018 10.1080/15622975.2018.1548782 0 0 0 76 10 SGSM2 29608557 PLoS Genet. 2018 PMC5897035 10.1371/journal.pgen.1007222 6 0 0 76 "Animals|Humans|*Body Mass Index|*Drosophila melanogaster|*Genome-Wide Association Study|*RNA Interference|SNPs|Obesity|Quantitative Trait Loci|Phenotype|Genetic Predisposition to Disease|Adipose Tissue|Adiposity|ARIH1 protein, human|Carrier Proteins|ZCCHC8 protein, human|Nuclear Proteins|VKORC1 protein, human|Vitamin K Epoxide Reductases" 10 SIPA1L3 30046524 Int J Ophthalmol 2018 PMC6048340 10.18240/ijo.2018.07.05 0 0 0 52 "*Cataract|Lens, Crystalline|DNA Methylation|Epithelial Cells" 10 SLX4IP 30480765 Cancer 2018 PMC6587451 10.1002/cncr.31837 6 0 0 57 "*Proteolysis|*Leukemia, Myeloid, Acute|*Genomics|Gene Expression Regulation, Leukemic|Prognosis|Mutation|Gene Expression Profiling|Genetic Predisposition to Disease|*Aneuploid|*Cell Cycle" 10 SLX4IP 30264502 Genes Chromosomes Cancer 2018 10.1002/gcc.22675 3 0 0 57 "Humans|*HPV 16|NFIX protein, human|*NFI Transcription Factors|Comparative Genomic Hybridization|*Anus Neoplasms|DNA, Viral|Papillomavirus Infections|Virus Integration|Carcinoma, Squamous Cell|Gene Expression|Viral Genome|BCAR3 protein, human|Adaptor Proteins, Signal Transducing" 10 TAPT1 29868985 Plant Cell Rep. 2018 10.1007/s00299-018-2307-4 2 0 0 15 *Triticum|*Tetraploidy|Ribulose-Bisphosphate Carboxylase|Phosphoenolpyruvate Carboxylase|Plant Roots|Plant Proteins|Photosynthesis|Plant Leaves|Phosphorus|Carbon Dioxide 10 TMEM207 30214895 Front Oncol 2018 PMC6125347 10.3389/fonc.2018.00350 1 24 0 20 "WWOX protein, human|*WW Domain-Containing Oxidoreductase|Tumor Suppressor Proteins|*Genes, Tumor Suppressor|TYRP1 protein, human|*Oxidoreductases|*Membrane Glycoproteins|*Cancers|Protein Binding|Signal Transduction|Carcinogenesis" 10 TSPAN17 30013551 Front Immunol 2018 PMC6036176 10.3389/fimmu.2018.01451 6 26 0 56 "Animals|Mice|*ADAM10 Protein|TSPAN32 protein, human|*Tetraspanins|Amyloid Precursor Protein Secretases|Membrane Proteins|ADAM Proteins|Protein Transport|Endoplasmic Reticulum|*Leukocytes|Substrate Specificity|Notch Proteins|Alzheimer Disease|Cells, Cultured|Scavenger Receptor|Adam10 protein, mouse" 10 TSPAN6 30279702 Front Genet 2018 PMC6153316 10.3389/fgene.2018.00396 1 1 0 135 Nonalcoholic Fatty Liver Disease|Lipid Metabolism|Hepatocytes|Liver|*Gene Expression|Triglycerides|Insulin Resistance|Liver Cirrhosis 10 TSPAN6 29716987 Mol. Cell Proteomics 2018 PMC6072545 10.1074/mcp.RA118.000608 3 0 0 135 "Animals|Mice|*Amyloid Precursor Protein Secretases|*Aspartic Acid Endopeptidases|*Biotinylation|*Click Chemistry|APLP1 protein, human|Amyloid beta-Protein Precursor|Alzheimer Disease|Neurons|*Cell Membrane|Nerve Tissue Proteins|Mice, Knockout|Proteolysis|Proteome|Membrane Proteins|Brain|Chl1 protein, mouse|Cell Adhesion Molecules|Bace1 protein, mouse" 10 USP27X 30341066 Cancer Res. 2018 10.1158/0008-5472.CAN-18-0753 9 5 0 51 "*Drug Resistance, Neoplasm|*Cell Migration|Epithelial-Mesenchymal Transition|Snail Family Transcription Factors|Neoplasm Invasiveness|Tumor Cell Lines|Transcription Factor|Gene Expression Regulation, Neoplastic|Neoplastic Stem Cells|Transforming Growth Factor beta|Ubiquitination|Cancer-Associated Fibroblasts|Transcriptional Activation|Signal Transduction|Upregulation|Downregulation|Deubiquitinating Enzymes" 10 USP27X 29497124 Oncogene 2018 PMC5955865 10.1038/s41388-018-0137-z 4 28 0 51 "*Carcinoma, Hepatocellular|CCNE1 protein, human|*Cyclin E|*Cyclin|*Liver Neoplasms|*Cell Transformation, Neoplastic|*Oncogene Proteins|*Cell Cycle Checkpoints|UBB protein, human|*Ubiquitin|*Tumorigenesis|peptidase E|*Aminopeptidases|tripeptide aminopeptidase|*Proliferating Cell Nuclear Antigen|Gene Expression Regulation, Neoplastic|Cell Cycle|Cell Proliferation" 10 ADIG 28826652 Injury 2017 10.1016/j.injury.2017.08.020 3 0 0 16 "Humans|*Bicycling|*Orthopedics|Motorcycles|Accidents, Traffic|Injury Severity Score|Multiple Trauma|Fractures, Bone|Hospitalization" 10 AP5Z1 29081410 Cancer Biomark 2017 10.3233/CBM-170541 0 0 0 46 "Humans|*Basal Cell Nevus Syndrome|*Whole Exome Sequencing|PTCH2 protein, human|Patched-2 Receptor|*Chinese|Patched-1 Receptor|Exome|Pedigree|Mutation|Genetic Linkage" 10 ATP13A3 28100167 BMC Genomics 2017 PMC5242001 10.1186/s12864-017-3488-x 8 4 0 63 Female|Male|Humans|Animals|Swine|Chickens|*Sperm|*Reproduction|Fallopian Tubes|Semen|Fertilization|Oviducts|Fertility|*Mammals|Uterus|cDNA Microarrays|Ovulation|Cervix Uteri|Vagina|*Cell Communication|Body Fluids 10 CNTLN 28854272 PLoS ONE 2017 PMC5576694 10.1371/journal.pone.0182885 5 6 0 162 "Humans|*Carcinoma, Non-Small-Cell Lung|*Afatinib|*Lung Neoplasms|Protein Kinase Inhibitors|ErbB Receptors|Erlotinib Hydrochloride|Gefitinib|Quinazolines|Drug Resistance, Neoplasm|Antineoplastic Agents|*Disease Progression|Mutation|EGFR protein, human" 10 CPXM1 28613228 Inflamm. Bowel Dis. 2017 10.1097/MIB.0000000000001066 10 0 0 24 "Humans|*Crohn Disease|*Transcriptome|*Intestinal Mucosa|Colitis, Ulcerative|*Sequencing, RNA|*Base Sequence|RNA, Messenger|*Whole Exome Sequencing" 10 DIRAS2 28806394 Oncogene 2017 PMC5730474 10.1038/onc.2017.280 2 67 0 36 "*Cell Cycle|RAP1GDS1 protein, human|Guanine Nucleotide Exchange Factor|*Cell Division|*Gene Expression|Small GTPases|MYBL2 protein, human|Cell Cycle Proteins|Cell Line, Tumor|*Cell Nucleolus|Lung Neoplasms|Protein Binding|RNAi|Cell Proliferation|Trans-Activators|Cell Movement|Nuclear Proteins" 10 DIRAS2 28270566 J. Neurosci. 2017 PMC5373140 10.1523/JNEUROSCI.0133-17.2017 14 0 0 36 "Mice|Animals|Humans|*Macaques|Alcohol Use Disorder|Ethanol|Alcohol Drinking|Orbitofrontal Cortex|Alcoholic|Neurons|*Biomarkers|PRRT2 protein, human|Membrane Proteins|Nerve Tissue Proteins|PRRT2 protein, mouse" 10 DIRAS2 28097908 World J. Biol. Psychiatry 2017 PMC5568996 10.1080/15622975.2017.1282175 6 3 0 36 Adult|Child|Humans|*Attention Deficit Disorder with Hyperactivity|Genetic Association Studies|Genetic Predisposition to Disease|*Biomarkers 10 DNAH6 29019003 J. Mol. Neurosci. 2017 10.1007/s12031-017-0984-z 0 1 0 8 "Mice|Animals|*Huntington Disease|*Dyneins|Huntingtin Protein|Trinucleotide Repeat Expansion|Nerve Tissue Proteins|Corpus Striatum|Nuclear Proteins|*Gene Expression|Disease Models, Animal|*Biomarkers|Cognitive Dysfunction|Signal Transduction" 10 DNAH6 28206990 Genet. Med. 2017 10.1038/gim.2016.225 15 0 0 8 Male|Humans|*Azoospermia|Spermatogenesis|Whole Exome Sequencing|Testis|Pedigree|Sperm|Mutation 10 EMC4 29069762 Oncotarget 2017 PMC5641105 10.18632/oncotarget.18234 4 21 0 30 "Mice|Animals|*Leukemia, Lymphocytic, Chronic, B-Cell|*Proto-Oncogene Proteins c-akt|*B-Lymphocytes|Agammaglobulinaemia Tyrosine Kinase|Receptors, Antigen, B-Cell|*Signal Transduction|Protein-Tyrosine Kinases|Pyrimidines|Pyrazoles|Protein Kinase Inhibitors|Cell Proliferation|Apoptosis|*Disease Models, Animal|Cell Line" 10 EMC4 28677085 3 Biotech 2017 PMC5496938 10.1007/s13205-017-0857-8 1 11 0 30 Humans|*Eukaryotic Initiation Factor-2B|*Saccharomyces cerevisiae|*Eukaryotic Initiation Factor-2|Saccharomyces cerevisiae Proteins|*tRNA|*Acetyltransferases|Amino Acid Sequence|Guanine Nucleotide Exchange Factors|Mutation|Protein Biosynthesis|Phosphorylation 10 EMC4 28342328 Ecotoxicol. Environ. 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Mutat. 2017 PMC5575512 10.1002/humu.23262 9 0 0 32 "Humans|*Cerebellar Ataxia|*Mitochondrial Dynamics|*Ataxia|*Myopathy|*Mutations|Disorders, Mitochondrial|Mitochondria|Mitochondrial Proteins|Phenotype|Pedigree|MSTO1 protein, human|Cytoskeletal Proteins|Cell Cycle Proteins" 10 MYZAP 29277685 Heart Rhythm 2017 10.1016/j.hrthm.2017.12.023 2 0 0 54 Humans|Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|*Fibrinogen|Colombia|*Complement|Desmoplakins|Skin|Endemic Diseases|*Hemostatics|Heart 10 MYZAP 29152726 Int. J. Dermatol. 2017 10.1111/ijd.13827 1 0 0 54 Pemphigus and fogo selvagem|*Pemphigus|*Autoantibodies|*Desmoplakins|Colombia|*Cell Junctions|South America|Skin|Endemic Diseases|Immunohistochemistry 10 MYZAP 29034528 Clin. Exp. 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Genome 2017 10.1007/s00335-017-9720-9 0 0 0 52 "Mice|Animals|*Cataract|Lens, Crystalline|Homozygote|*Eye Abnormalities|Exons|Heterozygote|Sequence Deletion|Mutation|Allele|SIPA1L3 protein, mouse|GTPase-Activating Proteins" 10 SLX4IP 31149201 Acta Endocrinol (Buchar) 2017 PMC6516578 10.4183/aeb.2017.364 0 0 0 57 "Humans|Female|*Diabetes Mellitus, Type 2|Genetic Linkage|*Chinese|Chromosome Mapping|Lod Score|Genetic Predisposition to Disease|Pedigree|Genome, Human|Phenotype|PAK7 protein, human|LAMP5 protein, human|Lysosome-Associated Membrane Glycoproteins" 10 TMEM207 29164763 J. Cell. Mol. Med. 2017 PMC5783854 10.1111/jcmm.13456 2 7 0 20 "*Carcinoma, Squamous Cell|*Mouth Neoplasms|WWOX protein, human|WW Domain-Containing Oxidoreductase|Tumor Suppressor Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Cell Hypoxia|*Genes, Tumor Suppressor|Tissues, Epithelial" 10 TMEM207 28666097 Am. J. Pathol. 2017 10.1016/j.ajpath.2017.05.002 3 0 0 20 "Humans|Mice|Animals|*Transgenic Mouse|*Mice, Inbred C57BL|*Disease, Polycystic Kidney|*Disease Models, Animal|Kidney|Mutation|Cysts|Promoter Regions, Genetic|TMEM207 protein, mouse|Membrane Proteins" 10 TMEM207 28422056 Int J Mol Sci 2017 PMC5412447 10.3390/ijms18040866 9 16 0 20 "*Adipokine|*Adiponectin|ITLN1 protein, human|*Lectins|*Cytokines|*Obesity|Leptin|*Carcinogenesis|Adipose Tissue|*GPI-Linked Proteins|Resistin|Colorectal Cancer|Colonic Neoplasms" 10 TMTC1 29147967 Interdiscip Sci 2017 10.1007/s12539-017-0272-1 2 0 0 95 *Inflammatory Bowel Disease|Gene Expression Profiling|Computational Biology|*Gene Expression|*Arthritis|Microarray Analysis|*In Silico|Ankylosing Spondylitis|Inflammation|Intestine 10 TMTC1 28973932 Proc. Natl. Acad. Sci. 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Chem. 2017 PMC5465482 10.1074/jbc.M116.765669 6 3 0 56 "Humans|Animals|Mice|*Antibodies, Monoclonal|TSPAN32 protein, human|*Tetraspanins|ADAM10 Protein|Amyloid Precursor Protein Secretases|ADAM Proteins|Protein Transport|Membrane Proteins|Endoplasmic Reticulum|Protein Binding|Cell Lines|Cells, Cultured|Substrate Specificity|Cell Movement|Signal Transduction|TSPAN5 protein, human" 10 TSPAN6 28600779 Hum. Genet. 2017 PMC5502059 10.1007/s00439-017-1821-8 39 1 0 135 "Humans|*Exome|Saudi Arabia|Nerve Tissue Proteins|Endoplasmic Reticulum|Golgi Apparatus|Receptors, Immunologic|Vesicular Transport Proteins|Sequencing, Whole Exome|Genes, Recessive|Homozygote|Mutations|Sequencing, Next-Generation|Sequence Analysis, DNA|Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cohort Studies|GRSF1 protein, human" 10 TSPAN6 28279219 Mol Neurodegener 2017 PMC5345265 10.1186/s13024-017-0165-0 17 16 0 135 *Amyloid beta-Protein Precursor|*Exosomes|*Lysosomes|Amyloid beta-Peptides|Secretase|Alzheimer Disease|Peptide Fragments|Neurons|Brain|Autophagy 10 TSPAN6 28207852 PLoS ONE 2017 PMC5312877 10.1371/journal.pone.0171968 4 8 0 135 "Humans|Female|Mice|Animals|*Synaptic Transmission|*Hippocampus|Long-Term Potentiation|Synapses|Excitatory Postsynaptic Potentials|Memory|Neuronal Plasticity|Receptors, AMPA|Presynaptic Terminal|Fear|Nerve Tissue Proteins|Membrane Proteins|Mice, Knockout|TSPAN6 protein, human|Tetraspanins" 10 ZNF142 28099906 Oncotarget 2017 PMC5362430 10.18632/oncotarget.14678 4 0 0 7 "Adenocarcinoma|Pancreatic Carcinoma|*Pancreatic Cancer|Keratin-6|Squamous Cell Carcinoma|Keratin-5|Lung Neoplasms|Immunohistochemistry|*High-Throughput Nucleotide Sequencing|Transcription Factors|Biomarkers, Tumor|DNA-Binding Proteins|Tumor Suppressor Proteins|*Genomics|Diagnosis, Differential" 10 ADIG 27914980 Gene 2016 10.1016/j.gene.2016.11.040 0 2 0 16 "Cattle|Animals|Adipocyte|Adipogenesis|Cell Differentiation|Satellite Cells, Skeletal Muscle|Adipose Tissue|Upregulation|Signal Transduction|Downregulation|Cells, Cultured|Membrane Protein|Cloning, Molecular" 10 ADIG 27802875 Am J Emerg Med 2016 10.1016/j.ajem.2016.10.046 4 0 0 16 "*Wounds, Nonpenetrating|*Diaphragm|Abdominal Injuries|Thoracic Injuries|Multiple Trauma|Wounds, Penetrating|Injury Severity Score|Rupture|Retrospective Studies" 10 ADIG 27766294 Data Brief 2016 PMC5067096 10.1016/j.dib.2016.09.034 0 0 1 16 "Mice|Animals|*Adipocyte|3T3-L1 Cells|Adipogenesis|Cell Differentiation|PPAR gamma|*Luciferase|Down-Regulation|Signal Transduction|*Real-Time Polymerase Chain Reaction|RNA, Messenger|SMAF1 protein, mouse|Nuclear Proteins" 10 ADIG 27374605 Am. 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Cardiol. 2016 10.1016/j.amjcard.2016.05.057 6 0 0 16 "Male|Humans|Young Adult|United States|Adult|Middle Aged|*Methamphetamine|Retrospective Studies|*Cardiomyopathy|Ventricular Dysfunction, Left|Stroke Volume|Heart Failure|Amphetamine-Related Disorders|Ventricular Function, Left|Heart Ventricles|Risk Factors" 10 ADIG 27354644 Anticancer Res. 2016 1 3 0 16 Mice|Animals|oligonol|*Catechin|*Litchi|*Metabolic Syndrome|*Fruit|*Phenols|*Polyphenols|*Liver|*Thinness|Plant Extracts 10 AP5Z1 27781213 Neurol Genet 2016 PMC5067938 10.1212/NXG.0000000000000111 0 0 0 46 "Humans|*Spastic Paraplegia|Spastic Paraplegia, Hereditary|Mutation" 10 AP5Z1 27606357 Neurol Genet 2016 PMC5001803 10.1212/NXG.0000000000000098 8 2 1 46 Humans|Hereditary Spastic Paraplegia|*Mutations|*Spastic Paraplegia|Genotype-Phenotype Correlations|Phenotype|Pedigree|Homozygote 10 ATP13A3 27429841 Am J Cancer Res 2016 PMC4937730 6 1 0 63 "Humans|*Eflornithine|CAV1 protein, human|*Caveolin 1|Polyamines|Antineoplastic Agents|Spermine|Spermidine|Putrescine|*Pancreatic Cancers|Cell Lines|Biological Transport|*Biomarkers|ATP13A3 protein, human|Adenosine Triphosphatases|Membrane Transport Proteins" 10 CEP128 27835906 Oncotarget 2016 PMC5349924 10.18632/oncotarget.13239 11 5 0 311 "Humans|*Exome|*Whole Exome Sequencing|*Transcriptome|*Lymphoma, Large B-Cell, Diffuse|Mutations|High-Throughput Nucleotide Sequencing|Genome, Human|DNA Copy Number Variations|Genomics|Genes, Regulator|Mutations, Missense|SLC1A4 protein, human|Amino Acid Transport System ASC" 10 CLCC1 27354342 Stem Cells 2016 PMC5053103 10.1002/stem.2411 9 8 0 118 "Humans|Adult|*Glioblastoma|Prospective Studies|Brain Neoplasms|Cancer Stem Cells|Cell Line, Tumor|Neural Stem Cells|*Transforming Growth Factor beta|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Differentiation|*Heme Oxygenase-1|Signal Transduction|Transcriptome Analyses|*Neoplastic Processes|HMOX1 protein, human|SCAMP3 protein, human|Carrier Proteins|Membrane Proteins" 10 CNTLN 27743375 Brain Imaging Behav 2016 PMC5392179 10.1007/s11682-016-9615-5 5 8 0 162 "Humans|Tomography, X-Ray Computed|*Cognitive Decline|Alzheimer Disease|*Amyloid|Amyloid beta-Peptides|*Amyloidosis|Neuroimaging|*Amyloidogenic Proteins|Positron Emission Tomography|Neuropsychological Tests|Cognition|Brain|Disease Progression|Executive Function|Longitudinal Studies|Episodic Memory" 10 CNTLN 27270507 Sci Rep 2016 PMC4897638 10.1038/srep27534 3 7 1 162 "Swine|Animals|*Pigmentation|Hair Color|Receptor, Melanocortin, Type 1|Phenotype|Alleles|Mutation|Breeding|Proto-Oncogene Proteins c-kit|Polymorphism, Single Nucleotide|China" 10 CNTLN 26915804 Biochem. 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Commun. 2016 10.1016/j.bbrc.2016.02.079 1 6 0 162 *Neurites|*Microtubules|*Microtubule-Associated Proteins|Tubulin|Centrosome|Centrioles|*Neurogenesis|Neurons|Cell Cycle Proteins|Nocodazole|Cell Line 10 CPXM1 27993161 Breast Cancer Res. 2016 PMC5168705 10.1186/s13058-016-0788-z 19 3 0 24 "*B-DNA|Cancer Screening|DNA, Neoplasm|*Epigenetic|Cell Free DNA|Biomarkers, Tumor|DNA Methylation|Polymerase Chain Reaction|Epigenesis, Genetic" 10 CPXM1 27006448 FASEB J. 2016 10.1096/fj.201500107R 4 8 0 24 "Humans|Male|Mice|Animals|*Adipogenesis|Adipocytes|Adipose Tissue|Cell Differentiation|Obesity|Mice, Obese|BAMBI protein, human|Membrane Proteins|*Carboxypeptidases|Cells, Cultured|Signal Transduction|Insulin" 10 DIRAS2 27364329 Neuropsychopharmacology 2016 PMC5101550 10.1038/npp.2016.113 0 1 0 36 "Humans|Child|*Attention Deficit Disorder with Hyperactivity|*Promoter Regions, Genetic|Gene Frequency|Allele|Genotype|Polymorphism, Single Nucleotide|Electroencephalogram|Event-Related Potentials" 10 DNAH6 26918822 PLoS Genet. 2016 PMC4769270 10.1371/journal.pgen.1005821 25 11 1 8 10 FAM208A 27391979 Clin. 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Genet. 2016 PMC5783298 10.1007/s00439-016-1747-6 12 0 0 15 "Child|Humans|*Phenotypes|*Cataract|Homozygote|Exome|Microcephaly|Mutations|Pedigree|Sequencing, Whole Exome|Cleft Lip|Genomics|Cohort Studies|TAF1A protein, human|Pol1 Transcription Initiation Complex Proteins" 10 TMEM207 26819645 J Cancer 2016 PMC4716854 10.7150/jca.13732 6 3 1 20 "Humans|ITLN1 protein, human|*Lectins|*Colorectal Carcinoma|*GPI-Linked Proteins|*Cytokines|Membrane Proteins|Prognosis|*Colonic Neoplasms|RNA, Small Interfering" 10 USP27X 27132940 Mol. 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Proteome Res. 2014 PMC4224986 10.1021/pr500421v 9 0 1 29 Humans|*Parkinson Disease|*Biomarkers|Sensitivity and Specificity|*Plasma|Disease Progression|Blood Proteins|Peptides|Unified Parkinson's Disease Rating Scale 10 PKHD1L1 24649974 Eur. J. Haematol. 2014 10.1111/ejh.12318 1 0 0 16 "Humans|*Leukemia, Large Granular Lymphocytic|*Genomics|*Gene Expression|Flow Cytometry|Mutation|*Biochemical Phenomena" 10 PPP1R14B 24898838 Am. J. Physiol. Regul. Integr. Comp. Physiol. 2014 PMC4121627 10.1152/ajpregu.00145.2014 9 0 1 139 "Animals|*Myosin-Light-Chain Phosphatase|*Computational Biology|Phylogeny|Exons|Muscle, Smooth|Isoforms|Splice Site, 3'|Alternative Splicing|RNA Splicing|Introns|Protein Subunits|Signal Transduction" 10 RALGAPA1 24814574 FEBS J. 2014 10.1111/febs.12836 4 2 1 46 Humans|Mitotic Spindle|Mitosis|Anaphase|Metaphase|Chromosome Segregation|GTPase-Activating Proteins|Cytokinesis|ral GTP-Binding Proteins|Cell Nucleus|HeLa Cells 10 RALGAPA1 24768767 Cell. Signal. 2014 10.1016/j.cellsig.2014.04.012 11 3 1 46 "Mice|Animals|*14-3-3 Proteins|RALA protein, human|*ral GTP-Binding Proteins|B-insulin|*Insulin|*Glucose Transporter Type 4|*Insulin, Regular, Human|*Muscle, Skeletal|GTPase Activating Protein|*Protein Transport|Signal Transduction|Glucose|Proto-Oncogene Proteins c-akt|Phosphorylation|3T3-L1 Cells|Adipocytes|rac1 GTP-Binding Protein|Muscle Cells" 10 RALGAPA1 24739889 PLoS ONE 2014 PMC3989219 10.1371/journal.pone.0094509 12 3 0 46 "Animals|*Polymorphism, Single Nucleotide|*Metagenomics|*Genome|*Genomics|Breeding|Genotype|Genetics, Population|Phenotype|Selection, Genetic|Chicken|*Oviposition|Eggs" 10 SLC35D3 24903652 Neuropsychopharmacology 2014 PMC4207346 10.1038/npp.2014.121 12 0 1 7 "Humans|Mice|Animals|*Corpus Striatum|L Dopa|Dyskinesia, Drug-Induced|Cholinergic Neuron|Interneurons|Parkinsonian Disorders|Neostriatum|Transgenic Mouse|Receptors, Dopamine D2|Cocaine|Slc35d3 protein, mouse|Monosaccharide Transport Proteins" 10 SLC35D3 24550737 PLoS Genet. 2014 PMC3923682 10.1371/journal.pgen.1004124 13 5 2 7 "Humans|Mice|Animals|*Dopamine|*Metabolic Syndrome|*Corpus Striatum|DRD1 protein, human|Receptors, Dopamine D1|*Neurons|*Signal Transduction|Receptors, Dopamine D2|*Mutation|Slc35d3 protein, mouse|Monosaccharide Transport Proteins" 10 TMEM207 25305140 Dis Model Mech 2014 PMC4257006 10.1242/dmm.017574 5 4 1 20 "Humans|Male|Female|Mice|Animals|Infant|*Transgenic Mouse|*Mice, Inbred C57BL|*Disease Models, Animal|Neoplasms, Adnexal and Skin Appendage|*Skin Neoplasms|Promoter Regions, Genetic|TFF3 protein, human|Intestinal Trefoil Factor|Stomach Neoplasms|TMEM207 protein, mouse|Membrane Proteins" 10 TMEM207 24717675 Am. 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Patterns 2013 10.1016/j.gep.2013.10.002 3 0 0 118 "Male|Mice|Animals|*Histones|*Spermatogenesis|Testis|Spermatogonia|Spermatocytes|Spermatids|Epigenesis, Genetic|Cell Differentiation|In Situ Hybridization|Embryonic Stem Cells|Adult Germline Stem Cells" 10 LHFPL3 24358143 PLoS ONE 2013 PMC3864906 10.1371/journal.pone.0082108 15 2 3 54 "Humans|*Glioma, Malignant|Anaplastic Astrocytoma|Glioblastoma|Brain Neoplasms|PTEN protein, human|PTEN Phosphohydrolase|Genes, p53|Mutations|Gene Amplification|Genomic Instability" 10 LMBR1L 23964685 Mol. Membr. 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Genet. 2013 10.1093/hmg/ddt447 4 0 1 57 "Male|Female|Child|Humans|*Sex Bias|RUNX1 protein, human|Core Binding Factor Alpha 2 Subunit|Proto-Oncogene Proteins c-ets|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|Repressor Proteins|*V(D)J Recombination|Basic Helix-Loop-Helix Transcription Factors|Proto-Oncogene Proteins|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Gene Deletion" 10 TAPT1 23637794 PLoS ONE 2013 PMC3630158 10.1371/journal.pone.0061172 30 0 5 15 Animals|*Chickens|*Genome-Wide Association Study|Beijing|*Meat|*Phenotype|*Body Composition|Quantitative Trait Loci|Genotype|SNPs|Pectoral Muscle|Abdominal Fat 10 APOLD1 23115050 Int. J. Cancer 2012 10.1002/ijc.27921 29 0 5 51 "*CpG Island|*DNA Methylation|*Colorectal Cancer|*Promoter Regions, Genetic|SRPUL protein, human|*Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Proto-Oncogene Proteins B-raf|*Membrane Proteins|Biomarkers, Tumor|Phenotype|Adenocarcinoma|*Colonic Neoplasms|*Genes, Regulator|MicroRNAs" 10 ATP13A3 22987659 Genes Chromosomes Cancer 2012 10.1002/gcc.22006 33 1 2 63 "Humans|Female|Comparative Genomic Hybridization|Cervical Intraepithelial Neoplasia|Cervical Cancer|*Cervix Uteri|Papillomavirus Infections|Papillomaviridae|HPV 16|*Oncogene|Cell Transformation, Viral|*Carcinogenesis|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|MicroRNAs|DNA Methylation|Gene Silencing|*Genes, Tumor Suppressor|Keratinocytes|ATP13A3 protein, human" 10 AVL9 22595670 Dev. Cell 2012 PMC3383995 10.1016/j.devcel.2012.04.010 47 13 4 130 "Humans|*Adherens Junctions|Endosomes|rab GTPases|Protein Transport|rab4 GTP-Binding Proteins|*Biological Transport|Transferrin|Endocytosis|Receptors, Transferrin|Cell Membrane|*Cell Migration|Membrane Proteins|HeLa Cells|Protein Binding|Cadherins|Rab14 protein, human" 10 CHIC1 25814834 Eur Phys J C Part Fields 2012 PMC4370953 10.1140/epjc/s10052-012-2251-3 2 0 0 60 Proton Therapy|Monte Carlo Method|Gamma Rays 10 CNTLN 22940680 J. 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Genet. 2012 PMC3487118 10.1016/j.ajhg.2012.08.027 20 0 1 29 "Male|Mice|Animals|Hedgehog Proteins|Acrocephalopolysyndactyly Type II|Transposition of Great Vessels|*Acrocephalosyndactylia|Signal Transduction|*Mutations|Polysyndactyly|Zebrafish|Phenotype|Abnormalities, Multiple|Craniosynostosis|Alleles" 10 MEGF8 22461890 PLoS ONE 2012 PMC3312890 10.1371/journal.pone.0033090 37 2 6 29 Animals|Mice|Humans|*Astrocytes|*Neurons|*Cell Death|Glial Fibrillary Acidic Protein|Brain Injury|Apoptosis|Cell Movement|Brain|*Protective Agents 10 MSTO1 23047795 Cancer Nurs 2012 PMC4665987 10.1097/NCC.0b013e318263f514 26 1 1 32 Humans|Male|Quality of Life|*Fatigue|*Prostatic Neoplasms|*Mitochondria|*Chronic Disease|*Gene Expression 10 RALGAPA1 22496769 PLoS ONE 2012 PMC3322132 10.1371/journal.pone.0033851 7 5 1 46 "Animals|*Chickens|*Reproduction|Avian Proteins|Eggs|*Phenotype|Oviposition|Quantitative Trait, Heritable|Genome-Wide Association Study|Haplotypes|Polymorphism, Single Nucleotide|Genome|*Biological Phenomena|GTP Phosphohydrolases" 10 SGSM2 23263489 Nat. 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Chem. 2012 PMC3464568 10.1074/jbc.M112.390401 11 16 1 135 "Humans|*Ubiquitination|*Signal Transduction|IRF3 protein, human|Interferon Regulatory Factor-3|TRAF3|DEAD Box Protein 58|Adaptor Proteins, Signal Transducing|DEAD-box RNA Helicases|Sendai virus|I-kappa B Kinase|*Receptors, Immunologic|Interferon-Induced Helicase, IFIH1|NF-kappa B|Immunity, Innate|RNA, Viral|HEK293 Cells|Tretinoin|Tetraspanins" 10 APOLD1 21510802 Thyroid 2011 10.1089/thy.2010.0217 10 0 1 51 *Arm|*Graves Ophthalmopathy|Adipogenesis|*Gene Expression|Adipocytes|Orbit|Adipose Tissue|Gene Expression Profiling|*Lymphedema 10 ATP13A3 22207337 Cell. Mol. Biol. Lett. 2011 PMC6275865 10.2478/s11658-011-0039-3 8 0 1 63 "Animals|Mice|*ATPase|*mRNA|Isoforms|Brain|Neurogenesis|Gene Expression Regulation, Developmental|Neurons|Cerebral Cortex|Hippocampus|Cerebellum|Aging|ATP13A2 protein, mouse|Membrane Proteins" 10 DIRAS2 21750579 Neuropsychopharmacology 2011 PMC3176568 10.1038/npp.2011.120 10 1 0 36 "Adult|Humans|Child|*Attention Deficit Disorder with Hyperactivity|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|*Phenotype|Genetic Association Studies|*Comorbidity|Haplotype|Personality Disorders|Bipolar Disorder|Genotype|Promoter Regions, Genetic|Personality" 10 FSIP2 22072270 J Neural Transm (Vienna) 2011 10.1007/s00702-011-0729-z 15 0 0 55 "Humans|*Genome-Wide Association Study|*Alcoholism|Australia|SNPs|*Withdrawal Symptoms|Haplotype|Genetic Predisposition to Disease|Linkage Disequilibrium|Gene Frequency|*Ethanol|Genotype|European Continental Ancestry Group|Phenotype|Family Health|KDM4C protein, human|Jumonji Domain-Containing Histone Demethylases" 10 GPR153 21981325 FEBS J. 2011 10.1111/j.1742-4658.2011.08388.x 6 0 2 12 "Humans|Mice|Animals|Phylogeny|*Arcuate Nucleus of Hypothalamus|*G-Protein-Coupled Receptors|Synteny|Sequence Alignment|Evolution, Molecular|Amino Acid Sequence|Genome|Rhodopsin|Chromosome Mapping|*Cerebellum|*Thalamus" 10 GXYLT2 22117070 J. 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Genet. 2011 PMC3155612 10.1111/j.1469-1809.2011.00664.x 11 0 2 76 "Adult|Humans|Child|Adolescent|Genome-Wide Association Study|Nutrition Surveys|Low Density Lipoprotein Cholesterol|Cholesterol, HDL|European Continental Ancestry Group|Triglycerides|African Continental Ancestry Group|African Americans|Polymorphism, Single Nucleotide|Mexican Americans|Genetic Variation|Lipids|Genotype|Phenotypes|Genotype-Phenotype Associations" 10 SLC35D3 21692051 Cancer 2011 PMC3123690 10.1002/cncr.25818 39 8 5 7 "Humans|*CpG Islands|*Carcinoma, Adenoid Cystic|*Salivary Gland Neoplasms|DNA Methylation|Gland, Salivary|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor" 10 TMTC1 21791083 BMC Med. 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Med. 2010 10 0 0 54 "Animals|Humans|*DNA Transposable Elements|Exon|Mutagenesis, Insertional|Gene Expression Regulation|Genome, Human|Transcription, Genetic|RNA, Antisense|Evolution, Molecular|Promoter Regions, Genetic|Primate|Retrovirus, Human Endogenous" 10 LHFPL3 20219702 Eur J Med Genet 2010 10.1016/j.ejmg.2010.02.003 4 0 0 54 "Humans|*Chromosomes, Human, Pair 7|*Chromosome Banding|Chromosome Deletion|Comparative Genomic Hybridization|Mental Retardation|Facies|Abnormalities, Multiple|Growth Disorders|Gene Deletion|In Situ Hybridization, Fluorescence|Haploinsufficiency|Phenotype|Syndrome|*Chromosome Structures|MLL5 protein, human|SRPK2 protein, human|Protein-Serine-Threonine Kinases" 10 TAPT1 21118569 BMC Genet. 2010 PMC3009607 10.1186/1471-2156-11-106 0 3 2 15 "Humans|Mice|Animals|*Chromosomes, Human, Pair 5|Ethylnitrosourea|Mutagenesis|Genes, Lethal|DNA Mutational Analysis|Mutation|Chromosome Mapping|Mice, Inbred C57BL|Genome|Genetic Complementation Test|*Genetic Techniques|Embryonic Development|Cloning, Molecular" 10 AVL9 19897736 Eukaryotic Cell 2009 PMC2805290 10.1128/EC.00184-09 3 0 0 130 "Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Golgi Apparatus|Vesicular Transport Proteins|Monomeric GTP-Binding Proteins|Endosomes|Protein Transport|Exocytosis|Signal Transduction|Protein Binding|Cell Membrane|Biological Transport|GTR2 protein, S cerevisiae" 10 CPA5 19849886 Parasitology 2009 10.1017/S0031182009991363 13 0 2 18 "*Histones|*Entamoeba histolytica|*Gene Silencing|Transcription, Genetic|Chromatin|amoebapore proteins, protozoan|Protozoan Proteins|Epigenesis, Genetic|Nucleosome|Lysine|Methylation|*Epigenetic|Open Reading Frames|Ion Channels" 10 GXYLT2 19940119 J. 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Biophys. 2020 10.1016/j.abb.2020.108467 0 0 0 76 "Humans|*Stomach Neoplasms|*tRNA|*Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Neoplastic Processes" 9 FBXO47 32409601 Proc. Natl. Acad. Sci. U.S.A. 2020 PMC7275758 10.1073/pnas.1918556117 0 0 0 76 Male|Animals|Germ Cells|Oogenesis|Sex Determination Processes|Gonads|Oryzias|Sperm|Vertebrates|Forkhead Transcription Factors 9 FBXO47 32057909 Gen. Comp. Endocrinol. 2020 10.1016/j.ygcen.2020.113435 0 0 0 76 "Animals|Male|*Sex Differentiation|Gonad|*Bass|Sex Determination Processes|Methyltestosterone|*Androgens|Testis|Spermatogenesis|RNA, Messenger|Gene Expression Profiling" 9 GLT6D1 32561905 Biol. Reprod. 2020 10.1093/biolre/ioaa084 0 0 0 2 Humans|Male|Female|Mice|Animals|*Testis|*CRISPR-Cas Systems|*CRISPR|Knockout Mouse|Spermatogenesis|Fertility|Sperm Motility|Gene Knockout Techniques|Proteins 9 GLT6D1 31925812 Clin. Exp. 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Genet. 2019 PMC6311919 10.1186/s12881-018-0723-5 0 4 0 180 "*Trichothiodystrophy, Nonphotosensitive 1|*Homozygote|Phenotype|Hair Diseases|Mutations|*Hypergonadotropic Hypogonadism|Mental Retardation|Adaptor Proteins, Signal Transducing" 9 NRBP2 31009519 PLoS ONE 2019 PMC6476534 10.1371/journal.pone.0215818 0 0 0 26 "Humans|*Cardiomyopathy, Dilated|*Left Ventricular Dysfunction|*Heart Failure|Stroke Volume|Angiotensin-Converting Enzyme Inhibitors|Heart Ventricles|Adrenergic beta-Antagonists|Myocardium|Heart|*Autophagy" 9 OTOP2 30954025 J Crohns Colitis 2019 PMC6535502 10.1093/ecco-jcc/jjz002 2 0 0 3 "Humans|*Colitis, Ulcerative|*Transcriptome|*Colon|*Intestinal Mucosa|*Colitis|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Biopsy|Real-Time Polymerase Chain Reaction|*Databases, Genetic" 9 OTOP2 30814735 Nature 2019 10.1038/s41586-019-0992-y 18 1 0 3 "Humans|*Inflammatory Bowel Disease|*Colon|Intestinal Mucosa|Cells, Epithelial|Goblet Cells|Colitis, Ulcerative|Inflammation|*B-Lymphocytes|Tight Junctions|Progenitor Cells|Mucus|Signal Transduction|WFDC2 protein, human|WAP Four-Disulfide Core Domain Protein 2" 9 OTOP2 30652071 FEBS Open Bio 2019 PMC6325572 10.1002/2211-5463.12554 1 2 0 3 "Humans|*Tumor Suppressor Protein p53|*Colorectal Cancer|*Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|*Mutation|Downregulation|Cell Line, Tumor|Cell Proliferation|*Colonic Neoplasms|Cell Transformation, Neoplastic|DNA|otopetrin 1 protein, human|Membrane Proteins|Phosphoproteins" 9 PAGE2 31831558 Clin. 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Biochem. 2018 10.1002/jcb.27285 4 0 0 94 "zinc-binding protein|SLC39A6 protein, human|Cation Transport Proteins|Zinc|*Transcriptome Analysis|*Colorectal Cancer|Homeostasis|Secretory Pathway|*Colonic Neoplasms|Upregulation|Neoplasm Proteins" 9 SLC39A11 30122198 Nutr Res 2018 10.1016/j.nutres.2018.04.014 0 0 0 94 Cross-Sectional Studies|zinc-binding protein|Republic of Korea|Diet|Triglycerides|Body Mass Index|High Density Lipoprotein Cholesterol|Single Nucleotide Polymorphisms|Risk Factors|Spices|Fasting|Gastritis|Eating|Cohort Studies 9 SLC45A1 30375717 Cancer Sci. 2018 PMC6317942 10.1111/cas.13853 8 4 0 3 "Humans|*Carcinoma, Squamous Cell|*Carcinoma, Non-Small-Cell Lung|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Oncogenesis|Gene Expression Profiling|Gene Knockdown Techniques|Prognosis|Disease-Free Survival|Cell Transformation, Neoplastic|Lung Neoplasms|MIRN144 microRNA, human" 9 SLC45A1 29467591 Cancer Cell Int. 2018 PMC5816515 10.1186/s12935-018-0521-3 3 1 0 3 "Humans|*Whole Exome Sequencing|*Neuroblastoma|Exome|Mutation|Biomarkers, Tumor|Drug Resistance, Neoplasm|Disease Progression|*Diploidy" 9 SLFN14 30536060 Curr Med Sci 2018 10.1007/s11596-018-1974-2 0 0 0 26 "Humans|*Atrial Septal Defect|*Mutations|Homeobox Protein Nkx-2.5|Chinese|Pedigree|Exome|GATA4 Transcription Factor|Genetic Predisposition to Disease|Sequencing, Whole Exome|Heart Defects, Congenital|Homeodomain Proteins|Amino Acid Sequence" 9 SLFN14 30431218 Haemophilia 2018 10.1111/hae.13638 4 0 0 26 Humans|*Whole Exome Sequencing|Exome|Phenotype|Myosin Heavy Chains|Genetic Predisposition to Disease|Mutation|*Blood Coagulation Disorders|*Hemorrhagic Diathesis 9 SLFN14 29678925 RNA 2018 PMC6004054 10.1261/rna.066415.118 1 0 0 26 "*Ribosomes|*Endoribonucleases|RNA, Ribosomal|RNA Processing, Post-Transcriptional|Thrombocytopenia|Megakaryocytes|Platelets|Mutation" 9 TMEM123 29511567 Pharmacol Res Perspect 2018 PMC5832900 10.1002/prp2.388 0 4 0 21 "Humans|Leukocytes, Mononuclear|*RNA|sulfamethoxazole hydroxylamine|*Sulphamethoxazole|Drug Hypersensitivity|Sulfonamides|Lymphocyte|Hydroxylamine|*Diagnostic Tests, Routine|Hydroxylamines|*Cytotoxicity, Immunologic|*Phenotypes|Apoptosis|Surrogate Marker" 9 TMPRSS11E 29530057 J. Exp. Clin. Cancer Res. 2018 PMC5848549 10.1186/s13046-018-0724-4 13 30 0 21 "*Esophageal Squamous Cell Carcinoma|long non-coding RNA TUSC7, human|*RNA, Long Noncoding|*Esophageal Neoplasms|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Carcinoma, Squamous Cell|Cell Movement|Cell Line, Tumor|3' Untranslated Regions|Gene Knockdown Techniques|Apoptosis" 9 TSC22D2 30126904 Development 2018 10.1242/dev.165324 3 5 0 214 Male|*Spermatogonia|*mTORC1|Spermatogenesis|Testis|Glial Cell Line-Derived Neurotrophic Factor Receptors|Transcription Factors|Stem Cells|Signal Transduction 9 TSC22D2 30053002 J. Anim. Sci. 2018 PMC6162586 10.1093/jas/sky289 2 0 0 214 Pregnancy|Female|Cattle|Animals|Genome-Wide Association Study|*Genomics|Breeding|Phenotypes|Genotype|Quantitative Trait Loci|Reproduction|Single Nucleotide Polymorphisms|Chromosomes|Fertility 9 UNC5CL 30071397 Comput Biol Chem 2018 10.1016/j.compbiolchem.2018.07.007 0 0 0 32 "Humans|*Irritable Bowel Syndrome|*Systems Biology|Phosphatidylinositol 3-Kinases|Phenotype|Genetic Predisposition to Disease|Colon|Transcriptome|Protein Interaction Maps|Proteins|Biomarkers|PRPF31 protein, human|Eye Proteins|BCLAF1 protein, human|Repressor Proteins|Tumor Suppressor Proteins|UNC5CL protein, human|Intracellular Signaling Peptides and Proteins" 9 ZFAND3 29451423 Physiol. Genomics 2018 PMC5966803 10.1152/physiolgenomics.00100.2017 1 0 0 28 "Humans|Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Saudi Arabia|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|Alleles|Genotype|European Continental Ancestry Group|Case-Control Studies|Transcription Factors|Cohort Studies" 9 40238 28054673 Sci Rep 2017 PMC5215504 10.1038/srep40238 0 0 0 0 *Lakes|Ecosystem|Soil|Water 9 ABCC13 28805618 Taiwan J Obstet Gynecol 2017 10.1016/j.tjog.2017.06.004 0 0 0 1 "Pregnancy|Humans|Female|*Mosaicism|*Prenatal Diagnosis|Amniocentesis|Comparative Genomic Hybridization|*Chromosome 2|Karyotyping|*Genetic Markers|Chromosome Duplication|In Situ Hybridization, Fluorescence|*Cytogenetics|Karyotype|Phenotype" 9 ADAD1 28145159 Scand. J. Rheumatol. 2017 10.1080/03009742.2016.1238959 1 0 0 1 "*Arthritis, Juvenile|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Alleles" 9 ANKZF1 28302725 J. Biol. Chem. 2017 PMC5427269 10.1074/jbc.M116.772038 2 1 0 33 "Humans|Child, Preschool|*Ankyrin Repeat|Inflammatory Bowel Disease 12|*Inflammatory Bowel Disease|*Mutations|Interleukin-10 Receptor alpha Subunit|Sequencing, Whole Exome|Exome|Genetic Association Studies|Genetic Predisposition to Disease|ANK2 protein, human|*Ankyrins|Phenotype|*Zinc Fingers|Zinc" 9 ASCL4 28334272 Carcinogenesis 2017 10.1093/carcin/bgx020 9 10 0 5 "Humans|*Oestradiol|*CoA, Long-Chain Acyl|Epithelial-Mesenchymal Transition|Glycogen Synthase Kinase 3|long-chain-fatty-acid-CoA ligase|Coenzyme A Ligases|*Receptors, Estrogen|ACSL6 protein, human|Estrogen Receptor alpha|MCF-7 Cells|Gene Expression Regulation, Neoplastic|TYRP1 protein, human|*Membrane Glycoproteins|Cell Line, Tumor|CDH1 protein, human|E Cadherin|Cell Movement|Cell Proliferation" 9 ASCL4 28123722 Mol Clin Oncol 2017 PMC5244854 10.3892/mco.2016.1094 7 2 0 5 "Humans|Male|Female|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Neoplastic|Cellular Proliferation|Colon Cancer|Lung Cancer|Oncogene|Glioblastoma|Cell Line, Tumor|Cell Transformation, Neoplastic|Brain Cancer" 9 CCSER1 28990359 Am. 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Genet. 2017 PMC5861711 10.1002/ajmg.b.32604 4 0 0 12 "Humans|Male|Female|*Alcoholism|Genome-Wide Association Study|*Alleles|European Continental Ancestry Group|African Americans|*Risk Behaviors|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Unprotected Sex" 9 CCSER1 28234981 PLoS ONE 2017 PMC5325534 10.1371/journal.pone.0172687 2 0 0 12 "Cattle|Animals|Male|*Polymorphism, Single Nucleotide|*RNA-Seq|Genome|*Whole Exome Sequencing|Sequencing, Next-Generation|Breeding|Sequence Analysis, DNA|Genomics|Chromosome Mapping|INDEL Mutation|Transcriptome|Liver" 9 CORO2B 29162887 Sci Rep 2017 PMC5698439 10.1038/s41598-017-15844-1 2 7 0 18 "Mice|Animals|*Podocytes|*Actin Cytoskeleton|Focal Adhesions|*WD40 Repeats|Glomerulosclerosis, Focal Segmental|Actins|Cytoskeleton|Knockout Mouse|Cell-Matrix Junctions" 9 CORO2B 28800606 PLoS ONE 2017 PMC5553726 10.1371/journal.pone.0183081 1 0 0 18 "Humans|*Whole Exome Sequencing|*Ciliopathy|*Phenotypes|Bardet-Biedl Syndrome|Genetic Association Studies|Kidney Diseases, Cystic|Mutations|Cilia|Eye Abnormalities|Genotype|Abnormalities, Multiple|Genetic Predisposition to Disease|High-Throughput Nucleotide Sequencing|LMO7 protein, human|Transcription Factors|LIM Domain Proteins|ALMS1 protein, human|Proteins" 9 DIP2B 29024729 Prog. Neuropsychopharmacol. Biol. Psychiatry 2017 10.1016/j.pnpbp.2017.10.003 6 0 0 33 "Humans|*Genome-Wide Association Study|*Quantitative Trait Loci|Genetic Predisposition to Disease|*Schizophrenia|Polymorphism, Single Nucleotide|Gene Expression" 9 DIP2B 28041903 Dev. Cell 2017 PMC6720111 10.1016/j.devcel.2016.12.001 19 3 0 33 "*Organogenesis|*Mesenchyme|Exosomes|RNA, Micro|Epithelium|Salivary Glands|Epithelial Cells|Cell Proliferation|Morphogenesis|Signal Transduction|*RNA Transport|Biological Transport" 9 Dnajc21 29146883 Blood 2017 10.1182/blood-2017-09-806489 36 0 0 43 "Child|Young Adult|Humans|Child, Preschool|*Germ-Line Mutation|*Bone Marrow Failure Disorders|*Pancytopenia|Myelodysplastic Syndromes|Anemia, Aplastic|Bone Marrow Diseases|Mutation|Phenotype|*Cohort Studies" 9 Dnajc21 28942353 Adv Biol Regul 2017 PMC6710477 10.1016/j.jbior.2017.09.002 14 5 0 43 Humans|*Shwachman-Diamond Syndrome|Cryoelectron Microscopy|Exocrine Pancreatic Insufficiency|Lipomatosis|Bone Marrow Diseases|60S Ribosomal Subunit|Ribosomes|Proteins|Mutations 9 EPHX3 28814981 Clin Epigenetics 2017 PMC5558660 10.1186/s13148-017-0386-7 12 23 0 13 "*Carcinoma, Squamous Cell|*Mouth Neoplasms|hydrogen sulfite|Sulfites|CpG Islands|DNA Methylation|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Early Detection of Cancer" 9 EPHX3 28384353 PLoS ONE 2017 PMC5383309 10.1371/journal.pone.0175348 4 2 0 13 "Animals|Mice|*Epoxide Hydrolases|Chromatography, Liquid|Tandem Mass Spectrometry|8,11,14-Eicosatrienoic Acid|Heart|arachidonate epoxygenase|Cytochrome P-450 Enzyme System|Epoxides|Ischemia-Reperfusion Injury" 9 FAM98A 28040436 Int. 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Sci. 2017 PMC5665448 10.1242/jcs.206904 5 9 0 75 "Humans|*Sirt1|F-Box Proteins|Ubiquitination|E3 Ubiquitin Ligase|SKP Cullin F-Box Protein Ligases|Proteolysis|Ubiquitin|Proteasome Endopeptidase Complex|EP300 protein, human|*E1A-Associated p300 Protein|Acetylation|Protein Binding|DNA-Binding Proteins|Protein Processing, Post-Translational|lipopolysaccharide B|*Lipopolysaccharides|HeLa Cells|PRMT1 protein, human" 9 FRRS1L 29276473 Front Mol Neurosci 2017 PMC5727121 10.3389/fnmol.2017.00402 3 19 0 22 Humans|Animals|Mice|*Dyneins|Proteomics|*Synaptic Transmission|AMPA Receptors|Neurons|Hippocampus|Brain|Membrane Proteins|Cell Membrane|Cognition Disorders|Oxidoreductases 9 FRRS1L 29086067 Curr Neurol Neurosci Rep 2017 PMC5662693 10.1007/s11910-017-0806-2 8 1 0 22 "Child|Humans|Movement Disorders|Developmental Disabilities|Phenotypes|Mutation|Sequencing, Next-Generation" 9 FRRS1L 28675162 Nat Commun 2017 PMC5500892 10.1038/ncomms15910 14 11 0 22 "Animals|Rats|Humans|*alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid|*Synaptic Transmission|glutamate receptor type B|Receptors, AMPA|Synapses|Neurons|Hippocampus|Membrane Proteins|Plasma Membrane|Protein Transport|Endoplasmic Reticulum|Brain" 9 GLT6D1 29105764 J. Periodont. Res. 2017 PMC5912940 10.1111/jre.12505 4 2 0 2 "Humans|Aggressive Periodontitis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Gene Frequency|Alleles|Case-Control Studies|FCGR3B protein, human|Receptors, IgG|GPI-Linked Proteins" 9 GPR63 28289782 Psychopharmacology (Berl.) 2017 10.1007/s00213-017-4586-9 7 0 0 30 "*Rhodopsin|GPRC5C protein, human|*G-Protein-Coupled Receptors|Ligands|Signal Transduction|*Neurology" 9 GTDC1 28365779 Hum. Mol. Genet. 2017 10.1093/hmg/ddw393 4 0 0 65 "Humans|*Induced Pluripotent Stem Cells|Neural Stem Cells|Neurons|Cell Differentiation|Autism Spectrum Disorders|*Neurodevelopmental Disorders|GTDC1 protein, human|Glycosyltransferases" 9 GTPBP1 28706494 Front Physiol 2017 PMC5489664 10.3389/fphys.2017.00455 1 4 0 312 "Rats|Animals|*Transient Receptor Potential Channels|*Odontogenesis|*Tooth Germ|Mesenchyme|Epithelium|Tooth|Gene Expression Regulation, Developmental|Cell Differentiation|Transcription Factors|In Situ Hybridization|Molar|Signal Transduction|RNA, Messenger" 9 HIGD2A 28630166 J. Cell. Sci. 2017 10.1242/jcs.198523 11 1 0 22 prohibitin|*Mitochondria|*Repressor Proteins|Mitochondrial Proteins|Inner Mitochondrial Membrane|Reactive Oxygen Species|Signal Transduction|Organelle 9 HIGD2A 28383048 Sci Rep 2017 PMC5382582 10.1038/srep46055 10 0 0 22 Cytochrome c Oxidase|Electron Transport Complex I|Electron Transport 9 IRAK1BP1 28883894 Clin Epigenetics 2017 PMC5581417 10.1186/s13148-017-0385-8 4 23 0 58 "Humans|*Aggressive Periodontitis|Cross-Sectional Studies|*Epigenesis, Genetic|*Inflammation|Cytokines|Lipopolysaccharides|DNA Methylation|Case-Control Studies" 9 KIAA1522 28794639 Onco Targets Ther 2017 PMC5538704 10.2147/OTT.S142610 3 10 0 54 "*Esophageal Cancer|Esophageal Squamous Cell Carcinoma|Carcinoma, Squamous Cell|*Esophagus|*Neoplastic Processes|Gene Expression Regulation, Neoplastic|Upregulation|Cell Line, Tumor|Cell Movement|RNA, Messenger|Xenograft Model Antitumor Assays" 9 KNDC1 28264072 PLoS ONE 2017 PMC5338823 10.1371/journal.pone.0173175 4 3 0 45 "Animals|Mice|*rasGEF|*Cerebellum|*Neurons|Synapses|Purkinje Cells|*Brain|Dendrites|Cerebellar Cortex|Mice, Knockout|Nerve Tissue Proteins|Cytoplasmic Granules|very-KIND protein, mouse|Guanine Nucleotide Exchange Factors" 9 MAGEH1 28516231 Mamm. Genome 2017 10.1007/s00335-017-9695-6 3 0 0 94 "Animals|*Phylogeny|*Mammals|*Evolution, Molecular|Syntenic Conservation|Xenarthra|Genome|BAGE protein, human|Antigens, Neoplasm|Sequence Alignment|Marsupialia|Amino Acid Sequence|MAGED1 protein, human|Exons|Opossum|Neoplasm Proteins|Eutherians" 9 MPLKIP 28913623 Arch. Dermatol. Res. 2017 10.1007/s00403-017-1780-x 0 0 0 180 "Humans|Ichthyosis follicularis atrichia photophobia syndrome|*Ichthyosis|Photophobia|Alopecia|Netherton Syndrome|Hypotrichosis|Trichothiodystrophy|*Ichthyosis, Lamellar|*Hair Diseases|Pedigree|Metalloendopeptidases|Nervous System|Phenotype|ERCC2 protein, human|Xeroderma Pigmentosum Group D Protein|MBTPS2 protein, human|MPLKIP protein, human|Adaptor Proteins, Signal Transducing" 9 PAGE2 28986743 Breast Cancer Res. Treat. 2017 10.1007/s10549-017-4520-1 2 2 0 8 "Humans|*Prognosis|In Situ Hybridization, Fluorescence|Retrospective Studies|Receptor, ErbB-2|Trastuzumab|Gene Amplification|Centromere|*Monosomy" 9 PAGE2 28742074 Transl Psychiatry 2017 PMC5538130 10.1038/tp.2017.160 4 0 0 8 Humans|*Prognosis|*Autoantibodies|Proteomics|*Psychosis|Schizophrenia|Bipolar Disorder|Diagnostic and Statistical Manual of Mental Disorders|Psychiatric Status Rating Scales|Recurrence|Remission Induction|Brain 9 plekhh2 29117201 PLoS ONE 2017 PMC5695603 10.1371/journal.pone.0187699 2 1 0 17 "Humans|*Whole Exome Sequencing|*Pedigree|*Venous Thromboembolism|*Risk Factors|*Thrombophilias|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Genome-Wide Association Study|Alleles|Genotype|Case-Control Studies" 9 PRAC1 29187560 Mol. Cancer Res. 2017 10.1158/1541-7786.MCR-17-0483 9 0 0 40 "Phosphatidylinositol 3-Kinases|Colon Cancer|Colorectal Cancer|*Colon|Prognosis|Biomarkers, Tumor|Retrospective Studies|Mutation" 9 PRAC1 29166888 BMC Ophthalmol 2017 PMC5700533 10.1186/s12886-017-0606-0 5 5 0 40 "*Apoptosis|Retinal Pigment Epithelium|Age Related Macular Degeneration|Cells, Cultured|*Cytokines|Vascular Endothelial Growth Factor A|Blotting, Western|Retinal Pigments|Epithelial Cells" 9 PRAC1 28651114 Stem Cell Res 2017 PMC5581994 10.1016/j.scr.2017.06.009 10 8 0 40 "Male|Adult|Humans|*Prostate|*Stem Cells|Spheroids, Cellular|Cell Separation|Cell Differentiation|Prostate Cancer|Cell Lines|Epithelial Cells|CDH1 protein, human|Antigens, CD|E Cadherin" 9 PRAC1 28557546 Epigenetics 2017 PMC5687324 10.1080/15592294.2017.1334023 9 0 0 40 "Humans|Male|*Colitis, Ulcerative|*DNA Methylation|*B-DNA|Colon|*Inflammation|Intestinal Mucosa|MutL Protein Homolog 1|Colorectal Neoplasms|Colonic Neoplasms|*Epithelium|Adenocarcinoma|Gene Expression Profiles|ROR1 protein, human|Receptor Tyrosine Kinase-like Orphan Receptors" 9 PRAC1 28487945 Mol Med Rep 2017 10.3892/mmr.2017.6516 2 21 0 40 "*Apoptosis|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Reactive Oxygen Species|CASP3 protein, human|Caspase 3|bcl-2-Associated X Protein|NADPH Oxidase 4|NADPH Oxidases|Epithelial Cells|Signal Transduction|Kidney Tubules|Annexin V|Glucose|Oxidative Stress|Upregulation|diphenyleneiodonium|Onium Compounds" 9 PRDM15 28740264 Nat. Genet. 2017 10.1038/ng.3922 4 2 0 26 Mice|Animals|Cellular Reprogramming|Embryonic Stem Cells|Mouse Embryonic Stem Cells|Induced Pluripotent Stem Cells|Cell Differentiation|Transcription Factors|DNA-Binding Proteins|Gene Expression Regulation|Zinc Finger|Signal Transduction|Binding Sites 9 SLC35F3 29113018 Mol. Ecol. 2017 10.1111/mec.14416 8 0 0 8 9 SLC38A6 28084903 Pharmacogenomics 2017 10.2217/pgs-2016-0184 4 0 0 14 "*Genome-Wide Association Study|*Cough|Sweden|*Angiotensin-Converting Enzyme Inhibitors|Gene Frequency|Polymorphism, Single Nucleotide|Hypertension" 9 SLC38A6 28040783 G3 (Bethesda) 2017 PMC5295616 10.1534/g3.116.037879 3 0 0 14 "Mice|Animals|*Carotid Atherosclerosis|Apolipoproteins E|*Mice, Inbred Strains|Atherosclerosis|Crosses, Genetic|Quantitative Trait Loci|Mice, Inbred C57BL|Triglycerides|Phenotype|Genetic Predisposition to Disease|*Multifactorial Inheritance" 9 SLC45A1 29220522 Hum. Mol. Genet. 2017 PMC5886212 10.1093/hmg/ddx416 6 7 0 3 "Humans|*Genome-Wide Association Study|SNPs|Genetic Predisposition to Disease|Genotype|DNA|Phenotype|*Hair|Cohort Studies|Genes, Homeobox|PTK6 protein, human|Neoplasm Proteins|Protein-Tyrosine Kinases|TCHH protein, human|Antigens|Intermediate Filament Proteins" 9 SLC45A1 28434495 Am. J. Hum. Genet. 2017 PMC5420346 10.1016/j.ajhg.2017.03.009 1 0 0 3 "Humans|*Intellectual Disability|*Glucose Transporter|*Epilepsy|Homozygote|Carbohydrate Metabolism, Inborn Errors|Exome|Pedigree|Phenotype|Monosaccharide Transport Proteins|Mutations|Mutation, Missense|SLC45A1 protein, human" 9 SLFN14 28734654 Immunobiology 2017 PMC5990420 10.1016/j.imbio.2017.07.002 4 46 0 26 "Mice|Animals|*Virus Replication|Orthomyxoviridae Infections|Influenza A virus|DDX58 protein, human|DEAD Box Protein 58|*Antiviral Agents|Type I Interferon|Influenza, Human|Epithelial Cells|Signal Transduction|A549 Cells|Cytoplasm" 9 SRFBP1 29188873 J Nutr Health Aging 2017 10.1007/s12603-017-0925-0 0 0 0 99 "*Serum Response Factor|*Actins|*Cytoskeletal Proteins|*Binding Protein|*Glucose|*Microfilaments, Actin|Transcription Factors|Cytoskeleton|Microfilament Proteins|Signal Transduction" 9 SRFBP1 29178545 Obesity (Silver Spring) 2017 PMC5740005 10.1002/oby.22074 3 4 0 99 "Male|Humans|Female|*Intra-Abdominal Fat|*Adiposity|*Genome-Wide Association Study|*Mexican Americans|*Obesity|Body Mass Index|Polymorphism, Single Nucleotide|Genotype|Phenotype|Alleles" 9 TMEM123 29234412 Evid Based Complement Alternat Med 2017 PMC5687148 10.1155/2017/5326909 2 9 0 21 "*Polyadenylation|jinfukang|*Herbal Medicine|*Drugs, Chinese Herbal|3' UTRs|*Lung Cancer|Gene Expression Profiling|*Phytotherapy|*Plants, Medicinal|*Genetic Profile|A549 Cells|High-Throughput Nucleotide Sequencing|Isoforms" 9 TMEM123 28893231 BMC Cancer 2017 PMC5594496 10.1186/s12885-017-3625-6 2 1 0 21 "Humans|Female|*Cystadenocarcinoma, Serous|*Carcinoma, Ovarian Epithelial|Neoplasms, Glandular and Epithelial|Ovarian Neoplasms|*Gene Fusions|Oncogene Proteins, Fusion|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Neoplasm Grading|Chromosome Aberrations|Transcriptomes|DPP9 protein, human|Dipeptidyl-Peptidases and Tripeptidyl-Peptidases" 9 TMPRSS11E 28693282 Oncol Lett 2017 PMC5494668 10.3892/ol.2017.6267 7 0 0 21 "Humans|*Urinary Bladder Neoplasms|Gene Regulatory Networks|Protein Interaction Maps|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Databases, Genetic|Computational Biology|Signal Transduction|Bladder" 9 trnp1 28860983 Front Comput Neurosci 2017 PMC5559440 10.3389/fncom.2017.00076 3 0 0 27 "Animals|Cerebral Cortex|Models, Neurological|Simulations, Computer|Brain|Neurobiology|Axons" 9 trnp1 28504339 FEBS Lett. 2017 PMC5509056 10.1002/1873-3468.12679 0 4 0 27 "Animals|Mice|Rabbits|*Rodents|*Central Nervous System|Protein Precursors|*Peptides|Amino Acid Sequence|Nerve Tissue Proteins|Brain|Opioid Receptor|Neurons|In Situ Hybridization|DNA, Complementary|mRNA|cDNA Library" 9 trnp1 28427208 Oncotarget 2017 PMC5438630 10.18632/oncotarget.15887 2 5 0 27 "Mice|Animals|*RNA, Long Noncoding|*C57BL Mouse|Phosphatidylinositol 3-Kinases|Network, Gene|*High-Throughput RNA Sequencing|mRNA|Gene Ontology|Gene Expression Profiling|*Heart|Computational Biology|Transcriptome|Gene Expression Regulation|Signal Transduction|Cell Proliferation|Regeneration" 9 trnp1 28199486 Invest. Ophthalmol. Vis. Sci. 2017 PMC5317276 10.1167/iovs.16-19767 6 5 0 27 "Mice|Animals|Retinal Bipolar Cell|Retina|*Interneurons|Retinal Cone Photoreceptor Cells|Homeodomain Proteins|Cell Differentiation|PRDM1 protein, human|Positive Regulatory Domain I-Binding Factor 1|Transcription Factors|Gene Expression Regulation, Developmental|Trnp1 protein, mouse|Nuclear Proteins" 9 ZFAND3 28580277 Mol Metab 2017 PMC5444093 10.1016/j.molmet.2017.03.011 13 9 0 28 "Humans|*Insulin Secretion|*Diabetes Mellitus, Type 2|Genome-Wide Association Study|*Insulin|Pancreatic beta Cells|*Insulin, Regular, Human|Cell Line" 9 38047 27897239 Sci Rep 2016 PMC5126667 10.1038/srep38047 8 3 0 0 "Humans|Female|HOTAIR long untranslated RNA, human|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Disease Progression|Proportional Hazards Models" 9 ABCC13 27342224 J. Exp. Bot. 2016 PMC5301939 10.1093/jxb/erw224 11 7 1 1 "*Triticum|*Phytic Acid|*Edible Grain|Seeds|Gene Expression Regulation, Plant|Plants, Transgenic|Plant Proteins|Germination|Plant Roots|*Organogenesis, Plant|Seedlings|*Membrane Transport Proteins" 9 ADAD1 27911851 Oncotarget 2016 PMC5340123 10.18632/oncotarget.10546 4 0 1 1 "Humans|Female|Animals|*Carcinoma, Ovarian Epithelial|*RNA Editing|*Ovarian Cancer|Neoplasms, Glandular and Epithelial|Single Nucleotide Polymorphisms|Adenosine Deaminase|Odds Ratios|Case-Control Studies|Genotype|Logistic Regression|SND1 protein, human|Nuclear Proteins" 9 ADAM18 27889101 Fertil. Steril. 2016 10.1016/j.fertnstert.2016.10.035 4 0 0 1 Humans|Female|*Exome|*Leiomyoma|Uterine Neoplasms|Mediator Complex|Leiomyosarcoma|*Whole Exome Sequencing|DNA Mutational Analysis|Mutations|Exons|*Genomics|Genetic Predisposition to Disease 9 CCSER1 27606429 PLoS ONE 2016 PMC5015895 10.1371/journal.pone.0161370 7 1 1 12 "Cattle|Animals|Male|*Polymorphism, Single Nucleotide|*RNA-Seq|Quantitative Trait Loci|*Whole Exome Sequencing|Breeding|Genomics|High-Throughput Nucleotide Sequencing|Transcriptome|Base Sequence" 9 DHRS4L2 27323117 Genet. Mol. Res. 2016 10.4238/gmr.15027752 2 0 0 6 "Humans|Mice|Animals|*CpG Islands|*Gene Cluster|Promoter Regions, Genetic|DNA Methylation|Transcription, Genetic|*Mammals|Cell Line, Tumor|Oxidoreductases|Genome|Bioinformatics|DHRS4 protein, human" 9 DHRS4L2 26864944 Sci Rep 2016 PMC4750091 10.1038/srep20961 20 16 1 6 "Humans|*RNA, Long Noncoding|*Gene Cluster|histone H3 trimethyl Lys4|Histones|Promoter Regions, Genetic|Transcription, Genetic|RNA Polymerase II|Transcription Start Site|*Regulatory Sequences, Nucleic Acid|Gene Duplication|DHRS4 protein, human|Oxidoreductases" 9 Dnajc21 27346687 Am. J. Hum. Genet. 2016 PMC5005432 10.1016/j.ajhg.2016.05.002 18 3 0 43 "Humans|Child|*Bone Marrow Failure Disorders|*Ribosome Subunits, Large, Eukaryotic|Bone Marrow Diseases|Anemia, Aplastic|Hemoglobinuria, Paroxysmal|*Mutations|*Pancytopenia|Myelodysplastic Syndromes|Leukemia, Myeloid, Acute|Genetic Predisposition to Disease|Ribosome|RNA, Ribosomal|DNAJC21 protein, human|HSP40 Heat-Shock Proteins" 9 Dnajc21 27185401 G3 (Bethesda) 2016 PMC4938669 10.1534/g3.116.028928 1 4 1 43 Animals|Humans|*Caenorhabditis elegans|*HSP40 Heat-Shock Proteins|Caenorhabditis elegans Proteins|*Locomotor Activity|Aldicarb|Synaptic Transmission|Acetylcholine|*Seizure|Phenotype|Mutation|Molecular Chaperone|gamma-Aminobutyric Acid|Glutamic Acid Decarboxylase 9 FAM98A 27896979 Pac Symp Biocomput 2016 PMC5146756 10.1142/9789813207813_0024 0 1 0 80 "Humans|*Diabetes Mellitus, Type 2|*African Americans|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Insulin Resistance|Insulin|Insulin Secretion|Genetic Predisposition to Disease|Genotype|Risk Factors|Atherosclerosis|FAM98A protein, human|Proteins" 9 FAM98A 27777970 JCI Insight 2016 PMC5070964 10.1172/jci.insight.86330 10 5 0 80 "*Lysosome|Endosomes|rab GTP-Binding Proteins|Osteoclasts|Protein Transport|*Bone|Adaptor Proteins, Signal Transducing|Membrane Glycoproteins|Protein Binding|*Homeostasis" 9 FBXL17 28007836 G3 (Bethesda) 2016 PMC5295603 10.1534/g3.116.036822 4 0 0 75 Animals|Sex Determination Processes|Flatfishes|Microsatellite Repeats 9 FBXL17 27234298 EMBO J. 2016 PMC4884786 10.15252/embj.201593374 12 59 1 75 "Humans|*Hedgehog Proteins|*Medulloblastoma|Zinc Finger Protein GLI1|*Signal Transduction|Kruppel-Like Transcription Factors|*Ubiquitylation|Repressor Proteins|*Transcription Factors|Cell Proliferation|Gorlin Syndrome|Cerebellar Neoplasms|SUFU protein, human|FBXL17 protein, human|F-Box Proteins" 9 FBXO47 27629089 Neurology 2016 PMC5067544 10.1212/WNL.0000000000003221 31 2 1 76 "Humans|*Multiple System Atrophy|*Genome-Wide Association Study|Genetic Predisposition to Disease|alpha-Synuclein|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Genotype|Alkyl and Aryl Transferases|Mutation" 9 FRRS1L 27707839 J. Natl. Cancer Inst. 2016 PMC5051943 10.1093/jnci/djw200 35 0 0 22 "*Prognosis|*RNA-Seq|*Lung Adenocarcinoma|Lung Cancer|Adenocarcinoma|RNA, Long Noncoding|Gene Expression Profiling|Biomarkers, Tumor|*Whole Exome Sequencing|Transcriptome|Kaplan-Meier Estimate|Disease-Free Survival|Gene Expression Regulation, Neoplastic|ROC Curve" 9 FRRS1L 27236917 Am. J. Hum. Genet. 2016 PMC4908178 10.1016/j.ajhg.2016.04.008 10 2 0 22 "Animals|Epilepsy|*Mutations|Receptors, AMPA|Neurotransmission|Brain|Nerve Tissue Proteins|*Epilepsy, Generalized|Movement Disorders" 9 FRRS1L 30713928 Mov Disord Clin Pract 2016 PMC6353394 10.1002/mdc3.12312 2 0 0 22 *Huntington Disease|*Chorea|Phenotype|Syndromes 9 FSCB 27440996 Mol. Vis. 2016 PMC4945165 4 1 0 7 "Hyperopia|Genome-Wide Association Study|Genetic Predisposition to Disease|Myopia|Genetic Association Studies|Polymorphism, Single Nucleotide|Refractive Errors|Ocular Refraction" 9 FSCB 27398160 Am J Transl Res 2016 PMC4931171 2 2 0 7 "Humans|Male|Animals|Mice|*Sperm Capacitation|*Phosphorylation|*Sumoylation|Sperm Motility|ROPN1 protein, human|*rho GTP-Binding Proteins|*Membrane Proteins|Protein Kinase A|Spermatozoa|Calcium-Binding Proteins|Tyrosine|CABYR protein, human|Phosphoproteins" 9 HIGD2A 27551323 Genes Nutr 2016 PMC4968440 10.1186/s12263-016-0537-z 2 18 1 22 "Animals|Humans|*Egg Yolk|*MCF-7 Cells|*Transcriptome|*Acids, Fatty|Linoleic Acids, Conjugated|Chickens|*Biological Phenomena|Cell Proliferation" 9 KIAA1522 27098511 Sci Rep 2016 PMC4838871 10.1038/srep24786 5 3 1 54 "Humans|*Carcinoma, Non-Small-Cell Lung|*Prognosis|*Lung Neoplasms|Biomarkers, Tumor|Kaplan-Meier Estimate|Antineoplastic Combined Chemotherapy Protocols|Proportional Hazards Models|Gene Expression Regulation, Neoplastic|Genes, ras|Mutation|Up-Regulation|Platinum|Risk Factor" 9 KNDC1 27456605 Sci Rep 2016 PMC4960555 10.1038/srep28836 2 15 1 45 Female|Animals|*Egg Shell|*Genome-Wide Association Study|Chickens|*Eggs|*Phenotype|SNPs|Haplotypes|Poultry|Chromosome 9 KNDC1 27066588 Neurol Genet 2016 PMC4817907 10.1212/NXG.0000000000000051 11 0 1 45 "Humans|*In Silico|*Epilepsy, Generalized|Genetic Association Studies" 9 LRFN5 27225731 Sci Rep 2016 PMC4881023 10.1038/srep26676 23 39 1 60 "*Synapses|Synaptic Transmission|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Cell Adhesion Molecules, Neuronal|AMPA Receptor|Nerve Tissue Proteins|*RNA Splicing|Neurogenesis|*Synapsis|Cell Adhesion Molecules|Ig Domains|Cell Differentiation" 9 MAGEH1 27851914 Immunity 2016 PMC5119953 10.1016/j.immuni.2016.10.021 90 1 0 94 "Humans|*T-Cells, Regulatory|Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Lymphocytes, Tumor-Infiltrating|Forkhead Transcription Factors|Prognosis|Th17 Cells|Kaplan-Meier Estimate|Immunotherapy|LAYN protein, human|Lectins, C-Type" 9 MPLKIP 26880286 BMC Med. Genet. 2016 PMC4754937 10.1186/s12881-016-0275-5 2 5 1 180 "*Trichothiodystrophy Syndromes|*Mitral Valve Insufficiency|*RNA Splicing|Homozygote|Pedigree|Phenotype|Mutation|Adaptor Proteins, Signal Transducing" 9 MRGPRF 27016783 Placenta 2016 10.1016/j.placenta.2016.02.015 6 0 0 14 "Humans|Infant, Newborn|Female|Pregnancy|*Pre-Eclampsia|*Gene Expression Profiling|Placentas|Oligonucleotide Array Sequence Analysis|Real-Time PCR, Quantitative|Gene Expression Profiles|*Biological Phenomena|Phenotypes" 9 NRBP2 27634758 Cancer Res. 2016 10.1158/0008-5472.CAN-16-0937 12 5 0 26 "*Carcinoma, Hepatocellular|*Proto-Oncogene Proteins c-akt|*Liver Neoplasms|*Signal Transduction|Cancer Stem Cells|Drug Resistance, Neoplasm|Cell Line, Tumor|Antineoplastic Agents|Gene Expression Regulation, Neoplastic|Xenograft Model Antitumor Assays|Apoptosis|Downregulation" 9 PAGE2 27587469 Cancer Immunol Res 2016 PMC5064839 10.1158/2326-6066.CIR-16-0013 25 1 1 8 "Humans|Female|Mice|Animals|*T Cell Receptor|Lymphocytes, Tumor-Infiltrating|CTLA4 protein, human|CTLA-4 Antigen|*Immunotherapy|Ipilimumab|T-Lymphocytes|Receptors, Antigen, T-Cell, alpha-beta|Complementarity Determining Regions|*Biomarkers|*Immunologic Factors|DNA Sequencing|High-Throughput Nucleotide Sequencing|*DNA" 9 plekhh2 27632998 J. 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Mol. Cell. Cardiol. 2016 10.1016/j.yjmcc.2016.09.013 6 1 0 17 "Mice|Rats|Animals|*Myocytes, Cardiac|Proteomics|*Energy Metabolism|Mitochondria, Heart|Adenosine Triphosphate|Ubiquitin-Protein Ligases|Heart Failure" 9 SAGE1 27246981 Oncotarget 2016 PMC5130022 10.18632/oncotarget.9636 10 3 1 162 "Humans|United States|*Carcinoma, Hepatocellular|*Asian Americans|*Liver Neoplasms|*European Continental Ancestry Group|Sorafenib|Mutation|Gene Expression Regulation, Neoplastic" 9 SLC35F3 27379158 Front Genet 2016 PMC4913099 10.3389/fgene.2016.00108 1 4 1 8 9 SLC35F3 27191787 Expert Rev Neurother 2016 10.1080/14737175.2016.1187562 4 4 0 8 9 SLC45A1 27431290 Mol. Psychiatry 2016 10.1038/mp.2016.113 40 0 0 3 "Humans|*Intellectual Disability|Exome|Genes, Recessive|Whole Exome Sequencing|Mutations|Homozygote|Genes, X-Linked|DNA Copy Number Variations|Sequence Analysis, DNA|Phenotypes|Genomics|Cohort Study|UBE4A protein, human|Ubiquitin-Protein Ligases|NUDT2 protein, human|Phosphoric Monoester Hydrolases" 9 SLFN14 27438527 Curr. Opin. Hematol. 2016 10.1097/MOH.0000000000000269 4 0 0 26 "Thrombopoiesis|Megakaryocytes|Thrombocytopenia|Blood Platelets|Mutations|*Databases, Genetic" 9 SRFBP1 27337995 Exp. Gerontol. 2016 PMC4969173 10.1016/j.exger.2016.06.008 0 46 0 99 "Mice|Humans|Animals|*Binding Protein|Endothelial Cells|*Serum Response Factor|Transcription Factors|Trans-Activators|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|*Aging|Mitochondria, Heart|Gene Expression Regulation|*Growth Hormone-Releasing Hormone|mRNA|Acetylation|Membrane Potential, Mitochondrial|Heart" 9 TMPRSS11E 26856390 Int. J. Cancer 2016 10.1002/ijc.30034 11 6 0 21 "Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Proto-Oncogene Proteins c-akt|*Apoptosis|*Downregulation|Signal Transduction|Carcinoma, Squamous Cell|Cell Line, Tumor|Cell Proliferation|Phosphorylation|*Cell, B-1|Serine Endopeptidases|Xenograft Model Antitumor Assays|*Genes, Tumor Suppressor|ErbB Receptors|EGFR protein, human" 9 trnp1 27264089 Nat Commun 2016 PMC4897765 10.1038/ncomms11812 17 2 1 27 "Humans|Animals|Pregnancy|Female|*Lateral Ventricles|Neocortex|Neurogenesis|CDH1 protein, human|*Cadherins|*Antigens, CD|Neuroglia|Neural Stem Cells|Radial Glial Cells|Neurons|Gene Expression Regulation, Developmental|Embryo, Mammalian|Ferret" 9 TSC22D2 27337956 Tumour Biol. 2016 10.1007/s13277-016-5113-z 19 1 0 214 "*Saccharomyces cerevisiae|Yeast Two-Hybrid Assay|*Yeast, Dried|Transcription Factors|Hybrid-B|Cell Cycle|*Plasminogen Activators|Protein Interaction Network|Cell Proliferation|Cell Line, Tumor" 9 TSC22D2 27573352 Int. 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Genet. 2016 10.1111/age.12459 4 0 0 214 Swine|Animals|*Genome-Wide Association Study|Genotype|Quantitative Trait Loci|Single Nucleotide Polymorphisms|Genetic Association Studies|Sus scrofa|Breeding|Phenotype|Chromosomes|Italy 9 TSC22D2 26785701 Sci Rep 2016 PMC4726286 10.1038/srep17958 15 8 1 214 "Humans|*Waist-Hip Ratio|*Waist Circumference|*Genome-Wide Association Study|*Asians|Body Mass Index|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Obesity|Genetic Loci|Abdominal Obesity|Genes, MHC Class II|EFEMP1 protein, human|Extracellular Matrix Proteins|CNPY2 protein, human|Adaptor Proteins, Signal Transducing|TSC22D2 protein, human|Carrier Proteins" 9 UNC5CL 26770579 Int J Clin Exp Med 2016 PMC4694479 6 0 0 32 "Humans|Genome-Wide Association Study|Case-Control Studies|*Esophageal Cancer|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Association Studies|Gene Frequency|Genetic Loci|Gastrointestinal Neoplasms|Risk Factors" 9 ZFAND3 27862917 Diabetes Metab. 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Cancer Res. 2015 10.1158/1078-0432.CCR-14-2744 17 1 6 54 "Humans|Child|*Sarcoma, Ewing|*Neuroectodermal Tumors, Primitive, Peripheral|RNA-Binding Protein EWS|Proteins, Oncogene Chimeric|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|Cell Line, Tumor|Mutation|Mutation Rate|High-Throughput Nucleotide Sequencing" 9 LRFN5 25690665 J. Alzheimers Dis. 2015 PMC4398648 10.3233/JAD-148009 12 5 0 60 "Humans|Aged|Genome-Wide Association Study|*Depression|Depressive Disorder, Major|Glycogen Synthase Kinase 3|European Continental Ancestry Group|Single Nucleotide Polymorphism|Antidepressant Drugs|Aging|Indiana" 9 MAGEH1 25694352 J. Neurooncol. 2015 PMC4436689 10.1007/s11060-015-1741-1 4 12 1 94 "Oligodendrogliomas|*Mutations|Isocitrate Dehydrogenase|Brain Neoplasms|DNA Helicases|Repressor Proteins|DNA-Binding Proteins|Chromosome Deletion|Gene Expression Regulation, Neoplastic" 9 MPLKIP 26518168 Eur J Med Genet 2015 10.1016/j.ejmg.2015.10.012 1 1 0 180 "Male|Humans|Female|Pregnancy|Young Adult|Adult|*Trichothiodystrophy Syndromes|Homozygote|Hair Diseases|Ichthyosis|Mutations|Phenotype|Pedigree|Exons|Mental Retardation|DNA Repair|Hair|Adaptor Proteins, Signal Transducing" 9 plekhh2 25759509 Mol. Cell Proteomics 2015 PMC4424407 10.1074/mcp.M114.046698 8 6 1 17 "Humans|*Signal Transduction|Plasma Membrane|Adaptor Proteins, Signal Transducing|Nerve Tissue Proteins|Protein Transport|Receptor, NK-2|Green Fluorescent Proteins|Protein Binding|*Biological Assay|CLIC4 protein, human|Channel, Chloride|Protein Interaction Domains and Motifs|HEK293 Cells|G-Protein-Coupled Receptors|HeLa Cells|CLIC2 protein, human|BAIAP3 protein, human" 9 RAB40AL 26300074 Mol Med Rep 2015 10.3892/mmr.2015.4215 0 0 0 59 "Humans|*Exome|*Mutation|Genetic Diseases, X-Linked|Intellectual Disability|Abnormalities, Multiple|Phenotype|Pedigree|Sequencing, Next-Generation|Genotype-Phenotype Correlation|ras Proteins|Hearing Loss, Sensorineural|Mutation, Missense|Mitochondrial Proteins|Mevalonate Kinase Deficiency" 9 RAB40AL 25956375 Gene 2015 10.1016/j.gene.2015.04.083 3 0 0 59 "Humans|Female|Child, Preschool|*Intellectual Disability|Comparative Genomic Hybridization|Chromosome Duplication|Chromosomes, Human, X|Abnormalities, Multiple|Dwarfism|*Chromosome Structures" 9 RNF207 25599194 Clin. Sci. 2015 PMC4557400 10.1042/CS20140663 7 0 0 17 "Humans|Mice|Rats|Animals|Early Detection of Cancer|TRIM63 protein, human|Tripartite Motif Proteins|*E3 Ligase|*Myocardial Infarction|Muscle Proteins|Troponin I|SKP Cullin F-Box Protein Ligases|UBB protein, human|Ubiquitin|*Biomarkers|Receiver Operating Characteristic|MicroRNAs|Proteasome|RNA, Messenger" 9 SAGE1 26252478 PLoS ONE 2015 PMC4529184 10.1371/journal.pone.0134967 1 1 1 162 "Humans|Male|*Testis|Antigens, Neoplasm|Lung Cancers|Neoplasm Proteins|Immunotherapy" 9 SLC39A11 26091520 PLoS ONE 2015 PMC4474865 10.1371/journal.pone.0128106 8 7 0 94 "Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|Neoplasms, Glandular and Epithelial|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genotype|Case-Control Studies|Risk Factors" 9 SLFN14 26280575 J. Clin. Invest. 2015 PMC4588283 10.1172/JCI80347 20 1 1 26 "Humans|*Thrombocytopenia|Platelet|*Hemostasis|*Mutations|*Hemorrhage|Mutations, Missense|*Leukopenia|Pedigree|Sequencing, Whole Exome|Heterozygote|desintegron B|*Betaine" 9 SLFN14 25996083 Biochemistry 2015 PMC4461289 10.1021/acs.biochem.5b00302 11 6 1 26 "Animals|Rabbits|*Reticulocytes|*Ribosome|*Endoribonucleases|RNA, Ribosomal|Ribosomal Proteins|Protein Biosynthesis|RNA|Binding Site|Mammals|mRNA" 9 SRFBP1 26319372 Trends Microbiol. 2015 10.1016/j.tim.2015.08.003 0 0 0 99 "*Hepatitis C virus|Proteomics|*Hepatitis C|Tetraspanin 28|Virus Internalization|TSPAN32 protein, human|Tetraspanins|Receptors, Virus|Membrane Proteins|Cell Line|Antigens, CD" 9 SRFBP1 26212323 Cell Rep 2015 PMC4836839 10.1016/j.celrep.2015.06.063 22 9 2 99 "Humans|*Hepacivirus|*Serum Response Factor|*Proteomics|*Hepatitis C|Tetraspanin 28|Virus Internalization|Receptors, Virus|Virus Binding|Hepatocytes|Host-Pathogen Interactions|Cell Line" 9 TMEM123 25881214 Heart Surg Forum 2015 10.1532/hsf.1214 0 0 0 21 "Humans|*Constriction, Pathologic|Genome-Wide Association Study|*Coronary Artery Bypass Grafting|Saphenous Vein|Graft Occlusion, Vascular|Vascular Patency|Coronary Angiography|*Transplants" 9 UNC5CL 26129866 Gut 2015 PMC5568652 10.1136/gutjnl-2015-309340 30 1 2 32 Humans|*Cardia|*Genome-Wide Association Study|*Stomach Neoplasms|*Adenocarcinoma|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Genotype|Case-Control Studies|Mucin-1|Risk Factors|Asia 9 ZC3H12C 26215033 J. Autoimmun. 2015 PMC4628849 10.1016/j.jaut.2015.07.008 88 18 3 108 "Humans|*Immunogenetics|*Psoriasis|Predispositions, Genetic|Adaptive Immune Response|Arthritis, Psoriatic|HLA-C*06 antigen|HLA-C Antigens|Genome-Wide Association Study|Skin|Immunity, Innate|Genes, rel|Th17 Cells|Genes, Regulator|STAT3 protein, human|STAT3 Transcription Factor|TNIP1 protein, human|DNA-Binding Proteins|ERAP1 protein, human" 9 ZC3H12C 26098909 PLoS ONE 2015 PMC4476619 10.1371/journal.pone.0128909 0 5 0 108 "Humans|Sheep|Dogs|Animals|*Genome-Wide Association Study|*Entropion|*Genome|Genotype|Breeding|Phenotype|Sheep, Domestic|Genetics, Population|Polymorphism, Single Nucleotide|Genomics|Genetic Markers|SLC2A9 protein, human|Glucose Transport Proteins, Facilitative|KCNB1 protein, human|Shab Potassium Channels" 9 ZC3H12C 26215033 J. Autoimmun. 2015 PMC4628849 10.1016/j.jaut.2015.07.008 88 18 3 108 "Humans|*Immunogenetics|*Psoriasis|Predispositions, Genetic|Adaptive Immune Response|Arthritis, Psoriatic|HLA-C*06 antigen|HLA-C Antigens|Genome-Wide Association Study|Skin|Immunity, Innate|Genes, rel|Th17 Cells|Genes, Regulator|STAT3 protein, human|STAT3 Transcription Factor|TNIP1 protein, human|DNA-Binding Proteins|ERAP1 protein, human" 9 ZC3H12C 26098909 PLoS ONE 2015 PMC4476619 10.1371/journal.pone.0128909 0 5 0 108 "Humans|Sheep|Dogs|Animals|*Genome-Wide Association Study|*Entropion|*Genome|Genotype|Breeding|Phenotype|Sheep, Domestic|Genetics, Population|Polymorphism, Single Nucleotide|Genomics|Genetic Markers|SLC2A9 protein, human|Glucose Transport Proteins, Facilitative|KCNB1 protein, human|Shab Potassium Channels" 9 40238 25176046 Mol Med Rep 2014 10.3892/mmr.2014.2518 0 1 0 0 "Humans|*Umbilical Veins|*Human Umbilical Vein Endothelial Cells|Urokinase-Type Plasminogen Activator|Plasminogen Activator Inhibitor 1|Fibrinolysis|Genetic Vectors|Tissue Plasminogen Activator|Adenoviridae|Cells, Cultured|*Blood Coagulation Factors|Endothelium, Vascular" 9 40238 25053905 Korean J Radiol 2014 PMC4105808 10.3348/kjr.2014.15.4.456 7 3 3 0 "Humans|Republic of Korea|*Tomography, X-Ray Computed|*Renal Insufficiency|Contrast Media|Kidney Diseases|Creatinine|Glomerular Filtration Rate|Risk Factors|Incidence|*Drug-Related Side Effects and Adverse Reactions|Prevalence|*Administration, Intravenous" 9 40238 25012550 J Subst Abuse Treat 2014 PMC4443912 10.1016/j.jsat.2014.05.002 5 0 0 0 "Humans|United States|*Criminal Law|*Risk Factors|*Abuse, Opioid|Crime|Bipolar Disorders|*Law Enforcement|Behavioral Problems|Medicaid|Massachusetts" 9 DIP2B 24760461 Carcinogenesis 2014 PMC4146415 10.1093/carcin/bgu092 24 0 3 33 "Humans|Genome-Wide Association Study|*Quantitative Trait Loci|*Colorectal Cancer|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Linkage Disequilibrium|*Colon Cancer|Colon|Genotypes|Genome, Human|Genes, Regulator|GPR143 protein, human|Eye Proteins|Membrane Glycoproteins" 9 EPHX3 24718283 Cancer Epidemiol. Biomarkers Prev. 2014 PMC4082437 10.1158/1055-9965.EPI-13-1000 11 4 1 13 "Humans|Male|*DNA Methylation|Neoplasm Recurrence, Local|*Prostate Cancer|Prostatectomy|Promoter Regions, Genetic|Prognosis|Homeodomain Proteins|Transcription Factors|Biomarkers, Tumor|Epigenetic" 9 FBXL17 24778558 Balkan J. Med. Genet. 2014 PMC4001410 10.2478/bjmg-2013-0026 2 0 1 75 "Male|Humans|*Genome-Wide Association Study|Single Nucleotide Polymorphisms|*Coronary Heart Disease|Genetic Predisposition to Disease|Genotype|Phenotype|Odds Ratio|*Genes, Regulator|Atherosclerosis|Risk Factors|Cardiovascular Disease|RTN4 protein, human|Nogo Proteins|FBXL17 protein, human|F-Box Proteins" 9 FBXL17 24528085 Asian Pac. J. Cancer Prev. 2014 10.7314/apjcp.2014.15.1.85 1 0 0 75 "Humans|*Polymorphism, Single Nucleotide|Genome-Wide Association Study|*Asian|Receptors, Estrogen|Receptors, Progesterone|Genetic Predisposition to Disease|Genetic Loci|Case-Control Studies|Genotype|Odds Ratio|Linkage Disequilibrium" 9 GLT6D1 24528298 J. Periodont. Res. 2014 10.1111/jre.12167 13 0 1 2 "Humans|*Genome-Wide Association Study|Aggressive Periodontitis|Genetic Predisposition to Disease|Chronic Periodontitis|Polymorphism, Single Nucleotide|Genotype|Genetic Loci|Phenotype" 9 IRAK1BP1 24418364 Mol. Cell. Neurosci. 2014 10.1016/j.mcn.2014.01.001 5 1 1 58 "Humans|anandamide|glyceryl 2-arachidonate|*Endocannabinoids|*HIV-1|HIV Infections|Arachidonic Acids|Polyunsaturated Alkamides|Glycerides|*Glia|*Immunity, Innate|Cannabinoid Receptor Agonists|Receptors, Cannabinoid|Cytokines|ZFP36 protein, human|Tristetraprolin|Inflammation|Neurons|Cells, Cultured" 9 KIAA1522 25304811 Mol. Biol. Rep. 2014 10.1007/s11033-014-3788-z 6 1 1 54 9 KIAA1522 25045014 Cancer Cytopathol 2014 10.1002/cncy.21461 4 0 1 54 "Early Detection of Cancer|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Small Cell Lung Carcinoma|*Biopsy|Bronchoscopy|Adenocarcinoma|Bronchi|Cytodiagnosis|Carcinoma, Squamous Cell|Biomarkers, Tumor|Sensitivity and Specificity" 9 KNDC1 24788352 Mol Med Rep 2014 PMC4068720 10.3892/mmr.2014.2201 5 12 1 45 "Humans|*Umbilical Veins|*Human Umbilical Vein Endothelial Cells|Cellular Senescence|Cyclin-Dependent Kinase Inhibitor p21|Tumor Suppressor Protein p53|Cyclin-Dependent Kinase Inhibitor p16|Cell Proliferation|Signal Transduction|Cell Cycle Arrest|ras Guanine Nucleotide Exchange Factor|*Protective Agents|Cells, Cultured|RNA, Small Interfering|G0 Phase|Extracellular Signal Regulated Kinases|KNDC1 protein, human" 9 MAGEH1 25366798 Genet. Mol. Res. 2014 10.4238/2014.October.31.22 2 0 0 94 "Humans|Infant, Newborn|*Turner Syndrome|*Real-Time Polymerase Chain Reaction|Quality of Life|Karyotyping|Neonatal Screening|Chromosomes, Human, X|Karyotype|ARSE protein, human|Arylsulfatases" 9 MPLKIP 25290684 J. Invest. Dermatol. 2014 PMC4530629 10.1038/jid.2014.440 7 3 2 180 Humans|*Trichothiodystrophy Syndromes|*Phenotype|*Mutations|Transcription Factor TFIIH|Hair Diseases|DNA Repair|Photosensitivity Disorders|Hair|Base Sequence 9 NRBP2 25209749 Part Fibre Toxicol 2014 PMC4354283 10.1186/s12989-014-0047-3 4 16 2 26 Humans|Male|Mice|Animals|titanium dioxide|*Titanium|*Apoptosis|Oxidative Stress|Reactive Oxygen Species|Lipid Peroxidation|Metal Nanoparticles 9 PAGE2 25229454 PLoS ONE 2014 PMC4168264 10.1371/journal.pone.0107905 5 6 1 8 "Humans|Male|*Testis|Caco-2 Cells|*Epigenesis, Genetic|*Epithelial-Mesenchymal Transition|Polycomb Repressive Complex 2|*Oncogenes|Promoter Regions, Genetic|Enhancer of Zeste Homolog 2 Protein|Histones|CDH1 protein, human|E Cadherin|Downregulation|DNA-Binding Proteins|Gene Expression Regulation, Neoplastic|Nuclear Proteins|Cell Differentiation|RNA Interference|Antigens, CD" 9 PRAC1 24628852 J Ovarian Res 2014 PMC3995551 10.1186/1757-2215-7-32 4 15 0 40 "Humans|Female|Mice|Animals|*Polycystic Ovary Syndrome|*Ovary|Anovulation|Dehydroepiandrosterone|Disease Models, Animal|Signal Transduction|RAC1 protein, human|rac1 GTP-Binding Protein" 9 RAB40AL 25370018 Eur. J. Pediatr. 2014 PMC4544553 10.1007/s00431-014-2452-x 1 0 0 59 "Male|*Genetic Diseases, X-Linked|*Abnormalities, Multiple|*Intellectual Disability|*Mutation|Pedigree|ras Proteins|*Hearing Loss, Bilateral|Mutation, Missense|*Musculoskeletal Abnormalities|Hearing Loss, Sensorineural|Heterozygote|Mitochondrial Proteins|Poland" 9 RAB40AL 25044830 Hum. Mutat. 2014 10.1002/humu.22620 2 0 0 59 "Humans|Male|Female|*Intellectual Disability|*Genetic Diseases, X-Linked|*Abnormalities, Multiple|*Genes, X-Linked|Mutation|Pedigree|Sequencing, Next-Generation|DNA Sequencing|*Hearing Loss, Bilateral|ras Proteins|DNA Mutational Analysis|*Musculoskeletal Abnormalities|Mutation, Missense|Mitochondrial Proteins|Poland" 9 RAB40AL 24863632 Eur. J. Pediatr. 2014 10.1007/s00431-014-2339-x 2 0 0 59 "Male|*Intellectual Disability|*Abnormalities, Multiple|*Genetic Diseases, X-Linked|*Hearing Loss, Sensorineural|*X-Linked Gene|*Mutation|*Musculoskeletal Abnormalities|*Hearing Loss, Bilateral|ras Proteins|Phenotype|Protein, Mitochondrial|Mutation, Missense|*Urinary Tract" 9 RNF207 25281747 J. Biol. Chem. 2014 PMC4256309 10.1074/jbc.M114.592295 12 2 0 17 "Animals|Humans|Rabbits|HEK293 Cells|*RING Finger Domains|ERG1 Potassium Channel|Ether-A-Go-Go Potassium Channels|Cardiomyocytes|TYRP1 protein, human|*Membrane Glycoproteins|Potential, Action|Protein Transport|Transfections|Ubiquitin-Protein Ligases|Membrane Protein|HSP70 Heat-Shock Proteins|Arrhythmias, Cardiac" 9 SAGE1 24795360 Cancer Immunol Res 2014 10.1158/2326-6066.CIR-13-0124 16 0 2 162 "Humans|Male|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|*Testis|*Testicular Neoplasms|Tumor Antigens|Squamous Cell Carcinoma|Immunohistochemistry|Adenocarcinoma|Biomarkers, Tumor|Membrane Proteins|Gastrointestinal Tract" 9 SLC25A36 25320081 J. Biol. Chem. 2014 PMC4246075 10.1074/jbc.M114.610808 17 0 2 76 "Humans|*Mitochondria|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|*Biological Transport|Mitochondrial Proteins|Inner Mitochondrial Membrane|Nucleotide Transport Proteins|DNA, Mitochondrial|Pyrimidine Nucleotides|Kinetics|Nucleotides" 9 SLC35F3 24509276 J. Am. Coll. Cardiol. 2014 PMC3992204 10.1016/j.jacc.2014.01.007 4 7 2 8 9 SLC38A6 24752331 PLoS ONE 2014 PMC3994050 10.1371/journal.pone.0095438 10 3 1 14 "Animals|Mice|*Synapses|*Neurons|Nerve Tissue Proteins|Membrane Proteins|Synaptic Membrane|Brain|Carrier Proteins|Cells, Cultured" 9 SLC39A11 24665060 J. Med. Genet. 2014 PMC4126189 10.1136/jmedgenet-2013-102151 0 2 4 94 "Adult|Male|Humans|Female|*Genome-Wide Association Study|*Smoking Behaviors|Smoking Cessation|Tobacco Use Disorder|Tobacco Use|*Ethnic Groups|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Prevalence|Bangladesh" 9 SLC45A1 25481369 Mol. Immunol. 2014 10.1016/j.molimm.2014.11.015 6 0 1 3 "Humans|Adult|*Genome-Wide Association Study|Pakistan|*Psoriasis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|HLA-C Antigens|Genotype|Case-Control Studies|*Ethnic Groups|TNIP1 protein, human|DNA-Binding Proteins|ELMO1 protein, human|Adaptor Proteins, Signal Transducing" 9 SLC45A1 25164149 Biochem. J. 2014 10.1042/BJ20140572 8 1 1 3 Male|Mice|Animals|*Sucrose|*Saccharomyces cerevisiae|*Protons|*Biological Transport|*Ion Transport|Monosaccharide Transport Proteins|Membrane Transport Proteins|*Mammals|prostein|Membrane Proteins|Symporters|Glucose|Plant|Fructose 9 SRFBP1 25183317 BMC Cell Biol. 2014 PMC4160719 10.1186/1471-2121-15-32 3 9 0 99 "Mice|Animals|Serum Response Factor|Transcription Factors|*Cytoskeleton|Nuclear Proteins|Trans-Activators|Amino Acid Sequence|Promoter Regions, Genetic|Cell Line" 9 TMEM123 24667120 J. Med. Genet. 2014 10.1136/jmedgenet-2014-102303 5 0 1 21 "Humans|*Genome-Wide Association Study|*Clubfoot|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Asian Continental Ancestry Group|Case-Control Studies|European Continental Ancestry Group" 9 TMPRSS11E 25122802 J. Virol. 2014 PMC4178745 10.1128/JVI.01427-14 26 0 4 21 "Humans|Mice|Animals|*Influenza A viruses|Influenza A Virus, H3N2 Subtype|*Coronaviruses|Influenza A Virus, H1N1 Subtype|*Virus Internalization|TMPRSS2 protein, human|Serine Endopeptidases|Hemagglutinin Glycoproteins, Influenza Virus|Orthomyxoviridae Infections|Virus Replication|Host-Pathogen Interactions|Serine Proteases|Surface Proteins|Middle East Respiratory Syndrome|Lung" 9 ZC3H12C 25481369 Mol. Immunol. 2014 10.1016/j.molimm.2014.11.015 6 0 1 108 "Humans|Adult|*Genome-Wide Association Study|Pakistan|*Psoriasis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|HLA-C Antigens|Genotype|Case-Control Studies|*Ethnic Groups|TNIP1 protein, human|DNA-Binding Proteins|ELMO1 protein, human|Adaptor Proteins, Signal Transducing" 9 ZC3H12C 25391383 J. Alzheimers Dis. 2014 PMC4324355 10.3233/JAD-142106 9 0 0 108 Humans|*Alzheimer Disease|Single Nucleotide Polymorphisms|Haplotype|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|*DNA Mutational Analysis|Genetic Testing|Case-Control Studies|Brain 9 ZC3H12C 25481369 Mol. Immunol. 2014 10.1016/j.molimm.2014.11.015 6 0 1 108 "Humans|Adult|*Genome-Wide Association Study|Pakistan|*Psoriasis|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|HLA-C Antigens|Genotype|Case-Control Studies|*Ethnic Groups|TNIP1 protein, human|DNA-Binding Proteins|ELMO1 protein, human|Adaptor Proteins, Signal Transducing" 9 ZC3H12C 25391383 J. Alzheimers Dis. 2014 PMC4324355 10.3233/JAD-142106 9 0 0 108 Humans|*Alzheimer Disease|Single Nucleotide Polymorphisms|Haplotype|Genetic Predisposition to Disease|Genetic Association Studies|Genotype|*DNA Mutational Analysis|Genetic Testing|Case-Control Studies|Brain 9 ZFAND3 25273842 Hum. Genet. 2014 PMC4225163 10.1007/s00439-014-1486-5 21 0 9 28 "Humans|United States|*Alleles|*African Americans|Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Transcription Factor 7-Like 2 Protein|*European Continental Ancestry Group|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Frequencies, Allele|Linkage Disequilibrium|Asian|Haplotypes|Case-Control Studies|Risk Factors|ADAMTS9 protein, human|ADAMTS9 Protein|Transcription Factors" 9 ABCC13 23738518 Genes Brain Behav. 2013 PMC3908370 10.1111/gbb.12053 28 2 2 1 Child|Humans|Adolescent|Young Adult|Adult|*Genome-Wide Association Study|*Reading|*Language|Longitudinal Studies|Australia|Dyslexia|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Phenotype|Cohort Studies 9 ADAD1 24066034 PLoS ONE 2013 PMC3774672 10.1371/journal.pone.0073176 9 3 1 1 "Animals|Male|*Scallops|Testis|Spermatogenesis|Gonad|Sex Differentiation|Gene Expression Profiling|Transcriptomes|Meiosis|Gene Library|*Nucleic Acid Hybridization|Gametogenesis|Subtractive Hybridization|ESTs|Gene Expression Regulation, Developmental|*Biological Phenomena|High-Throughput Nucleotide Sequencing" 9 ADAD1 23817569 Nat. Genet. 2013 PMC3753407 10.1038/ng.2686 98 4 11 1 "Humans|Cats|Animals|*Genome-Wide Association Study|*Self Report|*Allergy|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Pyroglyphidae|Asthma|Case-Control Studies" 9 ADAM18 23816990 Mol. Cell Proteomics 2013 PMC3820923 10.1074/mcp.M112.026476 12 0 3 1 Humans|Male|Mice|Animals|*Proteome|*Macaca mulatta|Phylogeny|*Sperm|Spermatogenesis|Epididymis|Testis|Sperm Maturation|Proteomics|Gene Ontology|Mass Spectrometry|Genome 9 ADAM18 23726833 Int. J. Dev. Neurosci. 2013 10.1016/j.ijdevneu.2013.05.003 1 0 0 1 "Pregnancy|Female|Humans|Infant, Newborn|Animals|Cattle|*Fetal Growth Retardation|*Transcriptome|Fetuses|Placenta|Stillbirth|Gene Expression Regulation, Developmental|*Infant, Small for Gestational Age|DNA Methylation|Kruppel-Like Transcription Factors|*Brain|mRNA|HtrA1 protein, human|High-Temperature Requirement A Serine Peptidase 1" 9 CCSER1 23830731 Cancer Genet 2013 PMC4030604 10.1016/j.cancergen.2013.04.006 7 4 1 12 "Humans|*Spectral Karyotyping|*Homozygote|Comparative Genomic Hybridization|*Sequence Deletion|Mesothelioma, Malignant|*Mesothelioma|*Lung Neoplasms|Chromosome Aberrations|Oligonucleotide Array Sequence Analysis|*Genomics|Chromosome Mapping|Karyotyping|Genome, Human|Cell Line, Tumor|Gene Deletion|Gene Expression Regulation, Neoplastic|DUSP7 protein, human|Dual-Specificity Phosphatases" 9 CCSER1 23665203 Am. J. Pathol. 2013 PMC3702746 10.1016/j.ajpath.2013.03.020 4 8 0 12 "Humans|Mitosis|Cytokinesis|Cell Cycle Proteins|Chromosomal Instability|Division Cycle, Cell|Cell Nucleus|Genes, cdc|Cancers|Phosphorylation|NDEL1 protein, human|Carrier Proteins" 9 FAM98A 24257188 Bioinformatics 2013 10.1093/bioinformatics/btt661 19 0 3 80 "Animals|calponin|Kinetochore|*Microfilament Proteins|*Calcium-Binding Proteins|NDC80 protein, human|Nuclear Proteins|Microtubules|Spindle Apparatus|Microtubule-Associated Proteins|Cell Cycle Proteins|Cytoskeletal Proteins|Mitosis|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Tubulin|Protein Structure, Tertiary|Amino Acid Sequence|NDC80 protein, S cerevisiae" 9 FBXL17 24035498 Mol. Cell 2013 PMC3981468 10.1016/j.molcel.2013.08.018 42 43 2 75 "Humans|*NF-E2-Related Factor 2|*Proteomics|Heme Oxygenase-1|Fanconi Anemia Complementation Group Proteins|Basic-Leucine Zipper Transcription Factors|Gene Activation|Oxidative Stress|RNA, Small Interfering|F-Box Proteins|RNA, Messenger|Cell Line|BACH1 protein, human|FBXL17 protein, human" 9 FRMPD1 23318951 J. Mol. Biol. 2013 10.1016/j.jmb.2013.01.003 9 2 0 16 "Protein Conformation|Protein Motif|Amino Acid Sequence|Binding Proteins|Protein Binding|Crystallography, X-Ray|Repetitive Sequences, Amino Acid|Binding Sites|Models, Molecular|PDZ Domain|Sequence Homology, Amino Acid|Tetratricopeptide Repeat" 9 FSCB 23695280 Eur. J. Hum. Genet. 2013 PMC3865415 10.1038/ejhg.2013.93 12 0 1 7 "Child|Humans|Adult|*DNA Copy Number Variations|*Cerebral Palsy|Genetic Predisposition to Disease|Exons|Gene Frequency|MCPH1 protein, human|Nerve Tissue Proteins|Databases, Genetic|DAAM1 protein, human|Adaptor Proteins, Signal Transducing" 9 FSCB 23303679 Biol. Reprod. 2013 PMC4434999 10.1095/biolreprod.112.105262 18 6 1 7 "Humans|Male|Animals|Mice|*Sperm Motility|*Phosphorylation|Sperm Tail|ROPN1 protein, human|*Membrane Proteins|*rho GTP-Binding Proteins|Sperm|A Kinase Anchor Proteins|cAMP Dependent Protein Kinase|Asthenozoospermia|Axoneme|Signal Transduction|Spermatogenesis|Infertility, Male" 9 GTDC1 24029077 Gene 2013 10.1016/j.gene.2013.07.067 1 0 0 65 "Humans|Mowat-Wilson syndrome|*Hirschsprung Disease|*Intellectual Disability|*Facies|*Microcephaly|Zinc Finger E-box Binding Homeobox 2|Homeodomain Proteins|Abnormalities, Multiple|Repressor Proteins|Mutation|Phenotype|Republic of Korea|Australia|Europe|GTDC1 protein, human|Glycosyltransferases" 9 GXYLT1 23765671 Methods Mol. Biol. 2013 10.1007/978-1-62703-465-4_23 3 0 0 87 *Glycosyltransferases|UDP xylose-protein xylosyltransferase|*Pentosyltransferases|Glycosylation|Substrate Specificity|Hydrolysis 9 IRAK1BP1 24165912 Circ Cardiovasc Genet 2013 PMC3952335 10.1161/CIRCGENETICS.113.000307 26 7 1 58 "Humans|*Genome-Wide Association Study|*Blood Pressure|Dietary Sodium|*Asian Continental Ancestry Group|Sodium Chloride, Dietary|Potassium, Dietary|Hypertension|Polymorphism, Single Nucleotide|Genotype|Potassium" 9 IRAK1BP1 24097067 Nat. Genet. 2013 PMC3867192 10.1038/ng.2792 117 8 11 58 "Humans|Sjogren's Syndrome|Histocompatibility Antigens Class II|STAT4 Transcription Factor|IRF5 protein, human|Interferon Regulatory Factors|Autoimmune Disease|Genetic Predisposition to Disease|Xerostomia|TNFAIP3 protein, human|Tumor Necrosis Factor alpha-Induced Protein 3|Histocompatibility Antigens|TNIP1 protein, human|DNA-Binding Proteins|FAM167A-BLK protein, human|ITSN2 protein, human|Adaptor Proteins, Vesicular Transport|TNPO3 protein, human|beta Karyopherins" 9 KIAA1522 23872981 Arch. Gynecol. Obstet. 2013 10.1007/s00404-013-2967-9 3 0 1 54 "Pregnancy|Infant, Newborn|Female|Humans|*Amniotic Fluid|*Proteomics|*Premature Birth|Preterm Premature Rupture of the Membranes|Fetal Membranes, Premature Rupture|Obstetric Labor, Premature|*Biomarkers|Proteome|Amniocentesis|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" 9 MRGPRF 23948647 Immunobiology 2013 10.1016/j.imbio.2013.07.001 11 0 2 14 "Humans|*Monocytes|*Lipopolysaccharides|*mRNA|*Macrophage|CSF1 protein, human|Colony-Stimulating Factor 1|sargramostim|Colony-Stimulating Factor, Granulocyte-Macrophage|*Cell Differentiation|TLR4 protein, human|Toll-Like Receptor 4|Macrophage Activation|*Inflammation|GPR101 protein, human|*G-Protein-Coupled Receptors|GPR15 protein, human|GPRC5A protein, human|*Hematopoiesis" 9 NRBP2 24140112 Am. J. Hum. Genet. 2013 PMC3824129 10.1016/j.ajhg.2013.09.010 26 0 2 26 "Humans|*DNA Copy Number Variations|Microcephaly|Intellectual Disability|*Phenotypes|Chromosome Deletion|Dwarfism|RNA Splicing Factors|Syndromes|Coloboma|Heart Defects, Congenital|Repressor Proteins|RNA Splicing|SCRIB protein, human|Membrane Proteins|Tumor Suppressor Proteins" 9 PRAC1 23385031 Free Radic. Biol. Med. 2013 10.1016/j.freeradbiomed.2013.01.031 22 4 4 40 "Male|Animals|Mice|*Myocardial Reperfusion Injury|*Tadalafil|*Phosphodiesterase 5 Inhibitors|*Cyclic Nucleotide Phosphodiesterases, Type 5|*Diabetes Mellitus, Experimental|Diabetes Mellitus, Type 2|*Oxidative Stress|Cardiomyocytes|*Protective Agents|Myocardium|Nitric Oxide|Apoptosis|Myocardial Infarction|Signal Transduction|Mitochondria|Sildenafil|Membrane Potential, Mitochondrial" 9 PRDM15 23616578 J. Immunol. 2013 PMC3703829 10.4049/jimmunol.1203471 4 1 0 26 "Humans|*Expressed Sequence Tags|*Genome|Transcriptome Analysis|Gene Library|Transcriptome|Sequence Analysis, DNA|Genomics|*Immune System|Cluster Analysis|mRNA" 9 RAB40AL 24209690 Clin Res Hepatol Gastroenterol 2013 10.1016/j.clinre.2013.09.002 0 0 0 59 "Humans|*Carcinoma, Hepatocellular|*Hepatitis B virus|*Liver Neoplasms|Hepatitis B, Chronic|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Haplotypes|Liver Cirrhosis|Gene Frequency|Alleles|Genotype|Case-Control Studies|*X Chromosomes" 9 SAGE1 24011616 Pathol. Res. Pract. 2013 10.1016/j.prp.2013.08.004 8 0 0 162 "Humans|Adult|Male|*Squamous Cell Carcinoma of Head and Neck|*Testis|*Squamous Cell Carcinoma|Antigens, Neoplasm|Head and Neck Neoplasms|Melanoma-Specific Antigens|Neoplasm Proteins|Immunohistochemistry|Biomarkers, Tumor|Testicular Neoplasms|Gene Expression Regulation, Neoplastic|SYCP1 protein, human|Nuclear Proteins|Membrane Proteins|*Neck" 9 SAGE1 23885216 Cancer Immun. 2013 PMC3721301 2 0 0 162 "Humans|Male|Adult|*Seminoma|*Testis|Testicular Germ Cell Tumor|*Testicular Neoplasms|Nonseminomatous germ cell tumor|*Tumors, Germ Cell|Embryonal Carcinomas|Yolk Sac Tumors|Teratomas|Neoplasm Proteins|*X Chromosome" 9 SLC38A6 24118318 Clin Oral Implants Res 2013 10.1111/clr.12266 6 0 0 14 "Humans|*Osseointegration|Bone-Implant Interface|Titanium|Surface Properties|Gene Expression Regulation|Prostheses and Implants|Osteocalcin|Acid Etching, Dental|Wound Healing|Microscopy, Electron, Scanning" 9 SLC39A11 24089422 J. Nutr. 2013 PMC3827636 10.3945/jn.113.184457 6 0 1 94 "Mice|Animals|zinc-binding protein|*Stomach|SLC39A4 protein, human|Cation Transport Proteins|*Zinc|*Colon|Gastric Glands|mRNA|Gastrointestinal Tract|Diet|Immunohistochemistry" 9 SLC39A11 23698163 Nutrients 2013 PMC3708345 10.3390/nu5051706 0 1 0 94 Male|Humans|Female|*Genome-Wide Association Study|*Selenium|European Continental Ancestry Group|Single Nucleotide Polymorphisms|African Americans|Genotype|Linear Models 9 SLC39A11 23643525 J. Nutr. Biochem. 2013 10.1016/j.jnutbio.2013.02.010 0 0 0 94 "Mice|Animals|zinc-binding protein|transcription factor MTF-1|Transcription Factors|DNA-Binding Proteins|Metallothionein|Zinc|Cation Transport Proteins|mRNA|Promoter Regions, Genetic|Response Element|Homeostasis|Biological Transport" 9 trnp1 23622239 Cell 2013 10.1016/j.cell.2013.03.027 82 1 9 27 "Humans|Mice|Animals|*Ependymoglial Cells|*Cerebral Cortex|Neuroglia|Neurons|*Mammals|Stem Cells|Cell Differentiation|Embryo, Mammalian|Fetus|Trnp1 protein, mouse|Nuclear Proteins" 9 ZC3H12C 23360436 Biochem. J. 2013 PMC3922049 10.1042/BJ20130019 13 40 1 108 Humans|Human Umbilical Vein Endothelial Cells|Signal Transduction|Tumor Necrosis Factor-alpha|I-kappa B Kinase|NF-kappa B|Vascular Cell Adhesion Molecule-1|Intercellular Adhesion Molecule-1|Transcription Factor RelA|Monocyte|Cell Adhesion|Phosphorylation|Inflammation|*Gene Expression|Anti-Inflammatory Agents|Leukocytes 9 ZC3H12C 23360436 Biochem. J. 2013 PMC3922049 10.1042/BJ20130019 13 40 1 108 Humans|Human Umbilical Vein Endothelial Cells|Signal Transduction|Tumor Necrosis Factor-alpha|I-kappa B Kinase|NF-kappa B|Vascular Cell Adhesion Molecule-1|Intercellular Adhesion Molecule-1|Transcription Factor RelA|Monocyte|Cell Adhesion|Phosphorylation|Inflammation|*Gene Expression|Anti-Inflammatory Agents|Leukocytes 9 ZFAND3 24086726 PLoS ONE 2013 PMC3783369 10.1371/journal.pone.0076317 21 0 4 28 "Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|Japan|*Asian|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Case-Control Studies|Genotype|*Epidemiologic Research Design" 9 ASCL4 22549224 Endocrinology 2012 10.1210/en.2011-2108 1 5 1 5 "*Angiotensin II|*Arachidonic Acid|*Aldosterone|Zona Glomerulosa|*Coenzyme A Ligases|*Cell Line|steroidogenic acute regulatory protein|Phosphoproteins|Mitochondria|Cells, Cultured|Steroids|RNA, Messenger|*Lipogenesis|Acyl Coenzyme A" 9 CASD1 22441673 Mol. Cells 2012 PMC3887797 10.1007/s10059-012-0017-2 4 0 0 27 "*Capsicum|*Tobacco|*Trichomes|*Ectopic Gene Expression|Gene Expression Regulation, Plant|Plant Proteins|*Cell Wall|Plant Leaves|Plant Diseases|Amino Acid Sequence|Gene Silencing|Plant Roots" 9 DHRS4L2 22891334 Proc. Natl. Acad. Sci. U.S.A. 2012 PMC3435198 10.1073/pnas.1116597109 39 4 6 6 "Humans|Animals|*Gene Cluster|RNA, Anti-Sense|Promoter Regions, Genetic|Transcription, Genetic|Gene Expression Regulation|Chromatin|DNA Methylation|Histone H3|Epigenesis, Genetic|RNA, Long Noncoding|DHRS4 protein, human|Oxidoreductases" 9 EPHX3 22798687 J. Lipid Res. 2012 PMC3435537 10.1194/jlr.M024448 27 0 2 13 "Humans|Animals|Mice|*Epoxide Hydrolases|*Epoxides|*Fatty Acids|lauric acid|Lauric Acids|8,11,14-Eicosatrienoic Acid|Xenobiotics|1-cyclohexyl-3-dodecylurea|Urea" 9 GPR63 23253088 BMC Med. Genet. 2012 PMC3556158 10.1186/1471-2350-13-123 9 1 1 30 "Humans|Child|*Tourette Syndrome|Tics|*Obsessive Compulsive Disorder|*Chromosome Mapping|Phenotype|*Base Sequence|Translocation, Genetic" 9 GTDC1 23152852 PLoS ONE 2012 PMC3494662 10.1371/journal.pone.0049084 11 1 2 65 "Humans|Female|Pregnancy|Cattle|Animals|Male|Mowat-Wilson syndrome|Intellectual Disability|Microcephaly|Facies|Hirschsprung Disease|*Syndrome|Heterozygote|Phenotype|Homeodomain Proteins|Genotype|Repressor Proteins|Abnormalities, Multiple|Mutation|Zinc Finger E-box Binding Homeobox 2|GTDC1 protein, human|Glycosyltransferases|ZEB2 protein, human" 9 GTDC1 22686481 Mol Cytogenet 2012 PMC3407782 10.1186/1755-8166-5-30 11 1 1 65 "Male|Humans|*Intellectual Disability|Comparative Genomic Hybridization|*Hypospadias|*Hernia, Umbilical|Autism Spectrum Disorder|Chromosome Deletion|Karyotyping|Gene Deletion|In Situ Hybridization, Fluorescence|*Chromosome Structures|Oligonucleotide Array Sequence Analysis|*High Blood Pressure" 9 GXYLT1 22872643 J. 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Biochem. 2012 10.1159/000339045 7 23 0 58 "Humans|*Receptor-Associated Kinase, IL-1|*Mesenchymal Stem Cells|NF-kappa B|Signal Transduction|Phosphorylation|TNF Receptor-Associated Death Domain Protein|Mitogen-Activated Protein Kinases|Tumor Necrosis Factor-alpha|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Lipopolysaccharides|Cyclooxygenase 2|Cell Proliferation|IRAK1 protein, human" 9 plekhh2 22832517 Kidney Int. 2012 10.1038/ki.2012.252 7 1 1 17 "Humans|*Podocytes|*Glomerulosclerosis, Focal Segmental|*Actins|Actin Cytoskeleton|Kidney Glomerulus|Lamellipodia|Focal Adhesions|*Downregulation|Proteinuria|Signal Transduction|Transcription Factors|Membrane Proteins|Cell Adhesion|Phosphorylation" 9 RAB40AL 22581972 J. Med. Genet. 2012 PMC3350147 10.1136/jmedgenet-2011-100575 4 2 0 59 "Humans|*Genetic Diseases, X-Linked|*Abnormalities, Multiple|*Intellectual Disability|*Genes, X-Linked|Mutation|Pedigree|Craniofacial Abnormalities|ras Proteins|*Hearing Loss, Bilateral|Phenotype|Hearing Loss, Sensorineural|Mutation, Missense|*Musculoskeletal Abnormalities|Mitochondrial Proteins|Amino Acid Sequence" 9 TSC22D2 22510880 EMBO J. 2012 PMC3365428 10.1038/emboj.2012.91 17 19 4 214 "Humans|Mice|Animals|*Intestine|*Progenitor Cell|*Homeostasis|Signal Transduction Pathways|Receptors, Cytoplasmic and Nuclear|Cell Transformation, Neoplastic|Vesicular Transport Proteins|Lineages, Cell|Cell Differentiation|Intestinal Neoplasms|Caenorhabditis elegans|Downregulation|NRBP1 protein, human|TSC22D2 protein, human|Carrier Proteins" 9 UNC5CL 22865593 Carcinogenesis 2012 PMC3584964 10.1093/carcin/bgs262 17 1 0 32 "Humans|*Esophageal Squamous Cell Carcinoma|Genome-Wide Association Study|Esophageal Neoplasms|Phosphoinositide Phospholipase C|Genetic Predisposition to Disease|Carcinoma, Squamous Cell|Polymorphism, Single Nucleotide|Chinese|Linkage Disequilibrium|*African Continental Ancestry Group|Genotype|Case-Control Studies|South Africa|UNC5CL protein, human|Intracellular Signaling Peptides and Proteins" 9 ZC3H12C 23143594 Nat. Genet. 2012 PMC3510312 10.1038/ng.2467 279 2 23 108 "Humans|Genome-Wide Association Study|*Psoriasis|CARD Signaling Adaptor Proteins|*Immunity, Innate|Guanylate Cyclase|Skin|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Keratinocytes|Membrane Proteins|Signal Transduction|Mutation|NF-kappa B|European Continental Ancestry Group|CARD14 protein, human" 9 ZC3H12C 23143594 Nat. Genet. 2012 PMC3510312 10.1038/ng.2467 279 2 23 108 "Humans|Genome-Wide Association Study|*Psoriasis|CARD Signaling Adaptor Proteins|*Immunity, Innate|Guanylate Cyclase|Skin|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Keratinocytes|Membrane Proteins|Signal Transduction|Mutation|NF-kappa B|European Continental Ancestry Group|CARD14 protein, human" 9 ANKZF1 21914798 J. Biol. Chem. 2011 PMC3207442 10.1074/jbc.M111.274506 33 1 4 33 "Humans|VCP protein, human|*Valosin Containing Protein|p97 ATPase|ATPase|Nuclear Proteins|Cell Cycle Proteins|Ubiquitin|AMFR protein, human|Receptors, Autocrine Motility Factor|Ubiquitin Ligase E3|Carrier Proteins|Amino Acid Sequence|Protein Binding|Binding Site|Adaptor Proteins, Signal Transducing|Proteolysis|Peptides|Protein Interaction Motif" 9 ANKZF1 21896481 J. Biol. Chem. 2011 PMC3207395 10.1074/jbc.M111.274472 22 1 2 33 "*Valosin Containing Protein|ATPase|Cell Cycle Proteins|Ubiquitin|Protein Structure, Tertiary|Carrier Proteins|Protein Binding|Amino Acid Motifs|Nuclear Proteins|Ubiquitin-Protein Ligases|Amino Acid Sequence|Adaptor Proteins, Signal Transducing|Crystallography, X-Ray|Substrate Specificity" 9 CASD1 21507905 Glycobiology 2011 10.1093/glycob/cwr050 11 0 1 27 "Humans|7-O-acetyl-GD3 ganglioside|*Gangliosides|*B-Lymphocytes|sialate O-acetylesterase|Acetylesterase|Lymphocyte Activation|Sialic Acids|Flow Cytometry|Antigens, CD|Lymphocytes|Glycosphingolipids|Palatine Tonsil|Acetylation|sialic acid O-acetyltransferase|Acetyltransferases|*Cell Differentiation|Apoptosis|Neu3 protein, human" 9 DIP2B 21251332 Genome Biol. 2011 PMC3091299 10.1186/gb-2011-12-1-r10 0 2 46 33 "Humans|*HapMap Project|*DNA Methylation|*B-DNA|CpG Islands|Epigenesis, Genetic|Quantitative Trait Loci|Gene Expression Regulation|Genome-Wide Association Study|Genome, Human|*Gene Expression|Polymorphism, Single Nucleotide|*Cell Lines|Genotype" 9 EPHX3 21692051 Cancer 2011 PMC3123690 10.1002/cncr.25818 39 8 5 13 "Humans|*CpG Islands|*Carcinoma, Adenoid Cystic|*Salivary Gland Neoplasms|DNA Methylation|Gland, Salivary|Promoter Regions, Genetic|Gene Expression Regulation, Neoplastic|Cell Line, Tumor" 9 FRMPD1 22074847 Proc. Natl. Acad. Sci. U.S.A. 2011 PMC3228485 10.1073/pnas.1110951108 26 5 2 16 "Humans|Animals|*Cell Polarity|glycylleucine|Binding Protein|ezrin|Cytoskeletal Proteins|radixin|Membrane Proteins|Spindle Apparatus|Cell Cycle Proteins|Intracellular Signaling Peptides and Proteins|Nuclear Matrix-Associated Proteins|Cell Division|Antigens, Nuclear|Protein Binding|Amino Acid Sequence|Asymmetric Cell Division|Models, Molecular|Frmpd1 protein, human" 9 FSCB 22006429 Cancer 2011 PMC3272156 10.1002/cncr.26617 23 4 3 7 *Phosphoinositide 3 Kinase|*Genotype|*Oncogenes|*Osteosarcoma|*Mutations|Phosphatidylinositol 3-Kinases|Class I Phosphatidylinositol 3-Kinases|Phosphatidylinositols 9 FSCB 21871179 BMB Rep 2011 10.5483/bmbrep.2011.44.8.541 3 3 0 7 "Humans|Male|Animals|Mice|*Sperm Capacitation|*Phosphorylation|Sperm Motility|Protein Kinase A|Spermatozoa|Cyclic AMP|Tyrosine|CABYR protein, human|Calcium-Binding Proteins|Phosphoproteins" 9 GTDC1 21821951 Biosci. Biotechnol. Biochem. 2011 10.1271/bbb.110124 1 0 0 65 "Animals|Humans|*Drosophila|glycolipid 3-alpha-mannosyltransferase|*Mannosyltransferases|cDNA|*Adenocarcinoma|*Colonic Neoplasms|Amino Acid Sequence|Base Sequence|Cloning, Molecular|Sequence Alignment|Sequence Homology, Amino Acid|Colon|Japan|Tokyo|GTDC1 protein, human|Glycosyltransferases" 9 GTPBP1 21515746 FASEB J. 2011 10.1096/fj.10-178715 8 0 0 312 "*mRNA|*Exosomes|mRNA Decay|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Protein Biosynthesis|Heterogeneous-Nuclear Ribonucleoproteins|3' Untranslated Regions|G Protein|Adaptor Proteins, Signal Transducing|Protein Binding|Guanosine Triphosphate" 9 GXYLT1 22117070 J. Biol. Chem. 2011 PMC3268431 10.1074/jbc.M111.302406 22 1 3 87 "Humans|Mice|Animals|*Xylose|*Epidermal Growth Factor|UDP xylose-protein xylosyltransferase|*Pentosyltransferases|NOTCH2 protein, human|Receptor, Notch2|Receptors, Notch|Drosophila|Glycosylation|Drosophila Proteins|Receptor, Notch1|Glucose|Repetitive Sequences, Amino Acid|Signal Transduction|Glycosyltransferases|Glucosyltransferases|*Cloning, Molecular|Endoplasmic Reticulum" 9 LRFN5 22031302 Am. J. Med. Genet. A 2011 10.1002/ajmg.a.34177 70 0 10 60 "Child|Humans|*Intellectual Disability|*Autism Spectrum Disorder|DNA Copy Number Variations|Developmental Disabilities|Comparative Genomic Hybridization|Autistic Disorder|Phenotypes|Gene Dosage|In Situ Hybridization, Fluorescence|CNTNAP2 protein, human|Nerve Tissue Proteins|Membrane Proteins|Cohort Studies" 9 LRFN5 21736948 Semin. Cell Dev. Biol. 2011 10.1016/j.semcdb.2011.06.005 18 14 4 60 "*Leucine|*Cell Adhesion Molecules|Cell Adhesion Molecules, Neuronal|Synapses|Neurons|Disks Large Homolog 4 Protein|*Protein Domains|Protein Binding|Axons|NMDA Receptors|Cell Differentiation" 9 MAGEH1 22197904 Invest New Drugs 2011 10.1007/s10637-011-9782-6 5 2 0 94 "Female|gemcitabine|dacomitinib|*Deoxycytidine|*Biliary Tract Cancer|*Quinazolinones|Antimetabolites, Antineoplastic|Apoptosis|Cell Line, Tumor|Cell Proliferation|Signal Transduction|Drug Synergism" 9 OTOP2 21261979 BMC Evol. Biol. 2011 PMC3038909 10.1186/1471-2148-11-23 5 8 0 3 "Animals|Mice|*Vertebrate|Evolution, Molecular|Synteny|Phylogeny|*Comparative Genomic Hybridization|Amino Acid Sequence|Multigene Family|Genome|Conserved Sequence|Fishes|Comparative Genomics|Models, Genetic|Sequence Homology, Amino Acid|Sequence Analysis, DNA" 9 SAGE1 22016418 Hum. Reprod. 2011 10.1093/humrep/der330 14 0 0 162 "Male|Adult|Humans|*Seminoma|*Testis|*Testicular Neoplasms|Antigens, Neoplasm|Neoplasm Proteins|Immunohistochemistry|*X Chromosome|Membrane Proteins|Germ Cells" 9 SAGE1 21706474 J. Pathol. 2011 PMC3210831 10.1002/path.2919 16 3 0 162 "Humans|Adult|Male|Aged|*Seminoma|*Spermatogonia|Testicular Neoplasm|Neoplasms, Germ Cell and Embryonal|Testis|Neoplasm Proteins|Antigens, Neoplasm|Spermatocytes|Cell Differentiation" 9 SAGE1 21437249 PLoS ONE 2011 PMC3060908 10.1371/journal.pone.0017876 36 0 2 162 "Humans|Male|*Testis|Receptors, Progesterone|Carcinoma, Ductal, Breast|Receptors, Estrogen|Receptor, ErbB-2|Carcinoma, Lobular|Biomarkers, Tumor|*Carrier Proteins|*Breast Neoplasms" 9 SLC25A36 21724286 Radiother Oncol 2011 10.1016/j.radonc.2011.05.068 8 0 0 76 "*High-Throughput Screening Assays|*Point-of-Care Systems|*Radiation Dosage|Oligonucleotide Array Sequence Analysis|Dose-Response Relationship, Radiation|Gene Expression|Gene Expression Profiling|Gamma Rays|mRNA|Radiation Tolerance|Quantitative Real Time PCR" 9 TMPRSS11E 21196187 Front Biosci (Landmark Ed) 2011 10.2741/3704 20 0 1 21 Humans|*Cancer|*Serine|Serine Endopeptidases|tripeptide aminopeptidase|*Aminopeptidases|endopeptidase B|*Cysteine Endopeptidases|Serine Proteases|Membrane Proteins|Disease Progression 9 UNC5CL 22158417 Cell Death Differ. 2011 PMC3307986 10.1038/cdd.2011.147 8 1 1 32 "*Myeloid Differentiation Factor 88|*Death Domain|IRAK4 protein, human|Interleukin-1 Receptor-Associated Kinases|IRAK1 protein, human|*Adaptor Proteins, Signal Transducing|*Signal Transduction|Tifab protein, human|TNF Receptor-Associated Factor 6|Nuclear Factor-Kappab|Receptor, Interleukin 1|Toll-Like Receptor|*Protein Domain|Protein-Serine-Threonine Kinases|Protein Kinases|Interleukin-1|Gene Expression Regulation|Transcription Factor" 9 ZFAND3 22158537 Nat. Genet. 2011 PMC3582398 10.1038/ng.1019 240 1 27 28 "Humans|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Asians|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Genotype|Case-Control Studies" 9 ZFAND3 21914466 Gene 2011 10.1016/j.gene.2011.08.021 3 0 1 28 9 ADAD1 20722033 Arthritis Rheum. 2010 PMC2970764 10.1002/art.27688 42 5 3 1 "*Arthritis, Juvenile|*Protein Tyrosine Phosphatase, Non-Receptor Type 2|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|STAT4 Transcription Factor|Genome-Wide Association Study|Genotype|Case-Control Studies|ANGPT1 protein, human|*Angiopoietin-1" 9 ASCL4 20119733 Obes Surg 2010 10.1007/s11695-010-0078-2 19 0 1 5 "Humans|*Non-alcoholic Fatty Liver Disease|*African Americans|*European Continental Ancestry Group|*Obesity|*Liver|Bariatric Surgery|Obesity, Morbid|*Gene Expression" 9 CASD1 20947662 Glycobiology 2010 PMC7108626 10.1093/glycob/cwq153 29 0 1 27 "Animals|Cricetinae|Humans|sialic acid O-acetyltransferase|*Acetyltransferases|Sialic Acid|Sialic Acids|ganglioside, GD3|Gangliosides|Acetylation|CHO Cells|Golgi Apparatus|Chromatography, High Pressure Liquid|CasD1 protein, human" 9 DHRS4L2 20525226 BMC Mol. Biol. 2010 PMC2892492 10.1186/1471-2199-11-43 2 0 1 6 "Humans|*Computational Biology|*Gene Cluster|Alternative Splicing|Transcription Initiation Site|Promoter Regions, Genetic|Transcription, Genetic|Base Sequence|Exons|RNA, Messenger|DHRS4 protein, human|Oxidoreductases" 9 GTDC1 20145308 J. Appl. Genet. 2010 10.1007/BF03195718 5 0 1 65 "Infant|Humans|Female|Mowat-Wilson syndrome|*Hirschsprung Disease|*Microcephaly|*Facies|*Intellectual Disability|Abnormalities, Multiple|Zinc Finger E-box Binding Homeobox 2|Homeodomain Proteins|Repressor Proteins|Phenotype|Heterozygote|Mutation|Syndrome|GTDC1 protein, human|Glycosyltransferases" 9 IRAK1BP1 20534545 Proc. Natl. Acad. Sci. U.S.A. 2010 PMC2895073 10.1073/pnas.1006894107 13 1 2 58 "Mice|Animals|NFKB1 protein, human|*p50, NF-kappa B|RELA protein, human|Transcription Factor RelA|*Inflammation|Toll-Like Receptor|NF-kappa B|Cytokines|Lipopolysaccharides|IL1R1 protein, human|*Receptors, Interleukin-1 Type I|TYRP1 protein, human|*Membrane Glycoproteins|Signal Transduction|Interleukin-10|I-kappa B Proteins|Macrophages|Cell Nucleus" 9 LRFN5 20648246 Mol Syndromol 2010 PMC2883852 10.1159/000280290 16 0 3 60 "Humans|Female|Young Adult|Adult|*Autistic Disorder|*Translocation, Genetic|Chromosome Breakage|Base Sequence|Chromosome Deletion|Intellectual Disability|Gene Expression|*Chromosome Structures|*Epigenesis, Genetic" 9 MAGEH1 20088962 Cancer Sci. 2010 10.1111/j.1349-7006.2009.01462.x 9 0 2 94 9 MRGPRF 21189161 BMB Rep 2010 10.5483/BMBRep.2010.43.12.830 11 0 3 14 "Humans|*Retinoic Acid|*Human Embryonic Stem Cells|*Epigenesis, Genetic|DNA Methylation|Embryonic Stem Cells|CpG Islands|Cell Differentiation|POU5F1 protein, human|Octamer Transcription Factor-3|Genome|Genes, Homeobox|Gene Expression Profiling|ELF3 protein, human|DNA-Binding Proteins|Transcription Factors|Proto-Oncogene Proteins c-ets|C10orf10 protein, human|C1qTNF6 protein, human" 9 plekhh2 20588063 Nephron Exp. Nephrol. 2010 10.1159/000317130 5 2 0 17 "Rats|Animals|*Puromycin Aminonucleoside|*Nephrosis|*Kidney Glomerulus|*Nephrotic Syndrome|nephrin|Membrane Proteins|Podocytes|Proteinuria|Intracellular Signaling Peptides and Proteins|Rats, Sprague-Dawley|Actinin|*Kidney Diseases|*Permeability" 9 SLC25A36 20944657 Genes Immun. 2010 10.1038/gene.2010.52 8 0 0 76 "Humans|*Genome-Wide Association Study|*Multiple Sclerosis|Spain|Genetic Predisposition to Disease|Allele|Gene Frequency|Genotype|Polymorphism, Single Nucleotide|Case-Control Studies|Odds Ratio|Cohort Studies|TRIB2 protein, human|Calcium-Calmodulin-Dependent Protein Kinases|Intracellular Signaling Peptides and Proteins|GPC5 protein, human|Glypicans" 9 SLFN14 20956525 J. Biol. Chem. 2010 PMC3001013 10.1074/jbc.M110.151076 25 0 2 26 "Humans|*Interferon-alpha|Melanoma|Gene Expression Regulation, Neoplastic|Melanocytes|Cell Line, Tumor|Cell Cycle Proteins|Cell Proliferation|Antiviral Agents|Drug Resistance, Neoplasm|RNA, Messenger" 9 TMEM123 20685650 J. Biol. Chem. 2010 PMC2951259 10.1074/jbc.M110.118877 2 0 1 21 "Mice|Animals|Tmem123 protein, mouse|*Membrane Proteins|Dendritic Cells|CD40 Antigens|*Cell Differentiation|Langerhans Cells|IL 12|Up-Regulation|Membrane Glycoproteins|B Cells|Signal Transduction|Protein Binding|Cell Line|RNA, Messenger|Cells, Cultured" 9 UNC5CL 20411297 Cell. Mol. Life Sci. 2010 10.1007/s00018-010-0371-1 5 2 0 32 *Spectrin|*Ankyrins|Erythrocyte Membrane|Lipid Bilayer|Erythrocytes|Protein Binding|Binding Sites|*Actin Cytoskeleton 9 UNC5CL 20230688 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010 0 0 0 32 "Humans|*Antibodies|Cloning, Molecular|Enzyme-Linked Immunosorbent Assay|Polymerase Chain Reaction|Genetic Vectors|*Prokaryotic Cells|Escherichia coli|UNC5CL protein, human|Intracellular Signaling Peptides and Proteins" 9 GLT6D1 19897590 Hum. Mol. Genet. 2009 10.1093/hmg/ddp508 50 1 3 2 "Male|Humans|*Genome-Wide Association Study|HEK293 Cells|Polymorphism, Single Nucleotide|Aggressive Periodontitis|Genetic Predisposition to Disease|Allele|Gene Frequency|Haplotype|Case-Control Studies" 9 GPR63 19286662 J. Biol. Chem. 2009 PMC2673301 10.1074/jbc.M806516200 118 2 5 30 "Cricetinae|Animals|*beta-Arrestin|lysophosphatidylinositol|Lysophospholipids|lysophosphatidic acid|G2A receptor|G-Protein-Coupled Receptors|*Protein Binding|sphingosine 1-phosphate|GPRC5C protein, human|Arrestins|Ligands|Sphingosine|Cricetulus|*Biological Assay|Receptor, Cannabinoid|*Protein Transport|CHO Cells|*beta-Arrestin 1" 9 GXYLT1 19940119 J. Biol. Chem. 2009 PMC2804315 10.1074/jbc.C109.065409 35 0 2 87 "Humans|Animals|UDP xylose-protein xylosyltransferase|*Epidermal Growth Factor|*Pentosyltransferases|*Glycosyltransferases|Receptors, Notch|Xylose|Drosophila Proteins|Glycosylation|Drosophila|Glucose|Repetitive Sequences, Amino Acid|UDP Xylose|Signal Transduction|Glucosyltransferases|*Immunotherapy, Adoptive|notch protein, Drosophila" 9 RNF207 19305409 Nat. Genet. 2009 PMC2976045 10.1038/ng.362 0 0 8 17 "Humans|Long QT Syndrome|KCNQ1 Potassium Channel|*Arrhythmias, Cardiac|NAV1.5 Voltage-Gated Sodium Channel|ERG1 Potassium Channel|Ether-A-Go-Go Potassium Channels|Sudden Cardiac Death|Genetic Variation|Mutation|Polymorphism, Single Nucleotide|Muscle Proteins|Heart|Electrocardiography|Genotype|Sardinia|CNOT1 protein, human|Transcription Factors|SETD6 protein, human" 9 RNF207 19305408 Nat. Genet. 2009 PMC2701449 10.1038/ng.364 0 7 11 17 "Humans|Genome-Wide Association Study|*Arrhythmias, Cardiac|KCNQ1 Potassium Channel|Long QT Syndrome|NAV1.5 Voltage-Gated Sodium Channel|ERG1 Potassium Channel|Ether-A-Go-Go Potassium Channels|Sudden Cardiac Death|Gene Frequency|Electrocardiogram|Genotype|Genetic Variation|Polymorphism, Single Nucleotide|Muscle Proteins|GINS3 protein, human|Chromosomal Proteins, Non-Histone" 9 SLC35F3 19252338 Drug Metab. Pharmacokinet. 2009 10.2133/dmpk.24.91 17 0 0 8 9 SLC38A6 19176878 Biol. Reprod. 2009 10.1095/biolreprod.108.075440 10 0 0 14 "Pregnancy|Sheep|Animals|Female|*Acidic Amino Acid Transporters|*Embryo Implantation|*Uteri|trophoblastin|Pregnancy Proteins|Endometrium|*Embryo, Mammalian|Progesterone|*Sheep, Domestic|Interferon Type I|Pregnancy, Animal|Estrous Cycle|mRNA|Gene Expression Regulation, Developmental|*Nutrients" 9 SRFBP1 19751705 Biochem. Biophys. Res. Commun. 2009 10.1016/j.bbrc.2009.09.031 2 3 0 99 "*Serum Response Factor|*Binding Protein|*HSP70 Heat-Shock Proteins|DNAJB1 protein, human|HSP40 Heat-Shock Proteins|Molecular Chaperones|Protein Binding|Amino Acid Sequence" 9 TMPRSS11E 19302215 FEBS J. 2009 10.1111/j.1742-4658.2009.06950.x 36 3 3 21 Humans|hepsin|matriptase 2|matriptase|*Substrate Specificity|*Serine Endopeptidases|*Membrane Proteins|*Peptides|Amino Acid Sequence|Peptide Library|Serine|Proteolytic Enzymes 9 UNC5CL 19328064 Mol. Cell 2009 10.1016/j.molcel.2009.02.016 32 1 1 32 "Protein Structure, Tertiary|Amino Acid Sequence|Protein Binding|*Cytoplasmic Structure|Signal Transduction|Ankyrin|Sequence Alignment|Crystallography, X-Ray|Apoptosis|Models, Molecular|Cytoplasm" 9 ABCC13 18691054 Curr. Med. Chem. 2008 10.2174/092986708785132870 92 0 4 1 "Humans|Endothelial Cells|multidrug resistance-associated protein 2|*Multidrug Resistance-Associated Proteins|ABCC6 protein, human|multidrug resistance-associated protein 3|ABCC5 protein, human|multidrug resistance-associated protein 1|Multidrug Resistance|ATP-Binding Cassette Transporters|*Drug Development|Biological Transport|Anticancer Agents|Cancer|Xenobiotics|Cell Membrane|Glutathione|Substrate Specificity|Blood-Brain Barrier" 9 ABCC13 18668432 Xenobiotica 2008 10.1080/00498250701883514 32 2 0 1 "Humans|*ATP-Binding Cassette Transporters|Multidrug Resistance-Associated Proteins|CFTR protein, human|Cystic Fibrosis Transmembrane Conductance Regulator|Biological Transport|Adenosine Triphosphate|Gene Expression|Mutations|Xenobiotics|ABCC11 protein, human" 9 ADAD1 20476959 Expert Rev Clin Immunol 2008 10.1586/1744666X.4.5.565 3 0 0 1 "*Genome-Wide Association Study|*Psoriasis|Arthritis, Psoriatic|IL23R protein, human|Receptors, Interleukin|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|HLA-C|Genes, MHC Class I|Major Histocompatibility Complex|Case-Control Studies|Genetic Linkage" 9 CORO2B 18925374 Subcell. Biochem. 2008 10.1007/978-0-387-09595-0_9 12 2 4 18 "Animals|coronin proteins|Drosophila melanogaster|*Microfilament Proteins|F-Actin|Amino Acid Sequence|Sequence Homology, Amino Acid|Phylogeny|coronin|4-Butyrolactone|Mammals|Protein Binding|Acanthamoeba|VCL protein, human|Vinculin" 9 DHRS4L2 18754758 Biosci. Rep. 2008 10.1042/BSR20080040 5 0 0 6 "Humans|*Gene Cluster|Transcription Start Site|Alternative Splicing|*RNA Splicing|Transcription, Genetic|Promoter Regions, Genetic|CpG Islands|Exons|Protein Isoforms|cDNA|Bioinformatics|RNA|DHRS4 protein, human|Oxidoreductases" 9 FBXL17 18820369 Cancer Genomics Proteomics 2008 6 1 0 75 "Humans|Electrophoresis, Gel, Two-Dimensional|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Cell Line, Tumor|Biomarkers, Tumor|Drug Resistance, Neoplasm|Specificity" 9 FRMPD1 18566450 J. Biol. Chem. 2008 PMC2529004 10.1074/jbc.M803497200 22 3 0 16 "Animals|Chlorocebus aethiops|erythrocyte membrane band 4.1 protein|*Membrane Proteins|*Signal Transduction|*Cytoskeletal Proteins|Heterotrimeric G-Proteins|Carrier Proteins|Cell Membrane|GTP-Binding Protein alpha Subunits, Gi-Go|GTP-Binding Protein Regulators|Guanine Nucleotide Dissociation Inhibitors|COS Cells" 9 IRAK1BP1 18268037 J. Exp. Med. 2008 PMC2271017 10.1084/jem.20071499 12 16 2 58 "Humans|Mice|Animals|Leukocytes, Mononuclear|*Mice, Inbred C57BL|*Toll-Like Receptor|Cytokines|Lipopolysaccharides|Macrophages|Interleukin-6|Inflammation Mediators|NF-kappa B|*Anti-Inflammatory Agents|Interleukin 1 Receptor Associated Kinase 1|Poly I-C|Signal Transduction|*Genetic Testing|mRNA" 9 NRBP2 18619852 Mol. Cell. Neurosci. 2008 10.1016/j.mcn.2008.05.013 8 2 0 26 "Humans|Child|Animals|Mice|*Cell Survival|Cell Differentiation|Neurons|Stem Cells|Brain|Cells, Cultured|Apoptosis|Medulloblastoma|Cell Proliferation|Hippocampus|Cerebellar Neoplasms" 9 OTOP2 18254951 BMC Evol. Biol. 2008 PMC2268672 10.1186/1471-2148-8-41 13 1 0 3 "Animals|*Invertebrate|Evolution, Molecular|Amino Acid Sequence|Multigene Family|Phylogeny|Zebrafish|Membrane Proteins|Otoliths" 9 plekhh2 18752002 Hum. Genet. 2008 10.1007/s00439-008-0548-y 5 0 0 17 "Humans|*Diabetic Nephropathies|Genome-Wide Association Study|Single Nucleotide Polymorphism|*Kidneys|Genetic Predisposition to Disease|Diabetes Mellitus, Type 1|Genotype|Case-Control Studies|Heterozygote|Promoter Regions, Genetic" 9 SLC25A36 18618715 Genes Chromosomes Cancer 2008 PMC2733213 10.1002/gcc.20590 32 2 0 76 "Humans|Female|*Uterine Cervical Neoplasms|Squamous Cell Carcinomas|Chromosome Aberrations|Adenocarcinomas|Karyotyping|*Genomics|In Situ Hybridization, Fluorescence|Cervix Uteri|Gene Mapping|DNA, Neoplasm|*Chromosomes|DTX3L protein, human|Ubiquitin-Protein Ligases|ATP2C1 protein, human|Calcium-Transporting ATPases" 9 SLC38A6 18418736 J. Mol. Neurosci. 2008 10.1007/s12031-008-9046-x 33 1 1 14 "Mice|Animals|Rats|*Transporters, Amino Acid|Amino Acid Transport Systems, Neutral|Amino Acids|Amino Acid Sequence|Biological Transport|Amino Acids, Neutral|In Situ Hybridization|Phylogeny|Liver|Slc38a1 protein, mouse|Amino Acid Transport System A|Slc38a1 protein, rat" 9 SRFBP1 18230186 BMC Cell Biol. 2008 PMC2268686 10.1186/1471-2121-9-8 6 13 0 99 *NADH Dehydrogenase|*Binding Protein|*NAD|Serum Response Factor|Transcription Factors|Amino Acid Sequence 9 ZC3H12C 18178554 J. Biol. Chem. 2008 10.1074/jbc.M707861200 81 4 5 108 "*Macrophages|NOS2 protein, human|Inducible Nitric Oxide Synthase|Macrophage Activation|Lipopolysaccharides|Nuclear Factor-Kappab|Tumor Necrosis Factor-alpha|Cytokines|PHF20 protein, human|Signal Transduction|Nitric Oxide|Promoter Regions, Genetic|*Biomarkers, Tumor|Short Interfering RNA|Zinc Fingers" 9 ZC3H12C 18178554 J. Biol. Chem. 2008 10.1074/jbc.M707861200 81 4 5 108 "*Macrophages|NOS2 protein, human|Inducible Nitric Oxide Synthase|Macrophage Activation|Lipopolysaccharides|Nuclear Factor-Kappab|Tumor Necrosis Factor-alpha|Cytokines|PHF20 protein, human|Signal Transduction|Nitric Oxide|Promoter Regions, Genetic|*Biomarkers, Tumor|Short Interfering RNA|Zinc Fingers" 9 38047 18055319 Bull Cancer 2007 0 0 0 0 Humans|Female|Mammography|*Screening|Surveys and Questionnaires|Feeling 9 DIP2B 17236128 Am. J. Hum. Genet. 2007 PMC1785358 10.1086/510800 0 0 2 33 "Humans|Fragile X Tremor Ataxia Syndrome|Fragile X Syndrome|*Chromosome Fragile Sites|Fragile X Mental Retardation Protein|Trinucleotide Repeat Expansion|Trinucleotide Repeats|DNA Methylation|*Chromosome 1|*Chromosome Structures|Promoter Regions, Genetic|Gene Expression|5' Untranslated Region|mRNA|Mental Retardation|Cytogenetic|Ataxia|Tremor" 9 FBXO47 17914060 Mol. Biol. Cell 2007 PMC2096575 10.1091/mbc.e07-03-0243 14 0 0 76 "Male|Humans|Animals|*Caenorhabditis elegans|*Meiosis|*Chromosome Pairing|Caenorhabditis elegans Proteins|Chromosomes|*Mitosis|Meiotic Prophase I|Germ Line|DNA Breaks, Double-Stranded|Cell Nucleus|Rad51 Recombinase|Recombination, Genetic|Mutations|Gonads|DNA Replication|Phenotype|rad-51 protein, C elegans|PROM-1 protein, C elegans" 9 FRMPD1 17404222 Proc. Natl. Acad. Sci. U.S.A. 2007 PMC1847458 10.1073/pnas.0701687104 30 0 2 16 "Female|Rats|Humans|Animals|*Quantitative Trait Loci|Alleles|Chromosome Mapping|Genetic Predisposition to Disease|Animals, Congenic|Mammary Neoplasms, Experimental|9,10-Dimethyl-1,2-benzanthracene|*Risk|Phenotype|Comparative Genomics|Case-Control Studies|FBXO10 protein, human|F-Box Proteins|Frmpd1 protein, human|Carrier Proteins" 9 FSCB 17855365 J. Biol. Chem. 2007 10.1074/jbc.M702238200 10 2 1 7 "Humans|Male|Rats|Mice|Animals|*Protein Kinase A|*Phosphorylation|Sperm Flagellum|*Calcium-Binding Proteins|Spermatids|Spermatogenesis|Sperm|Sperm Capacitation|Testis|Seminal Plasma Proteins|Amino Acid Sequence|Phosphoproteins|Cloning, Molecular|CABYR protein, human" 9 LRFN5 17303092 Brain Res. 2007 10.1016/j.brainres.2007.01.033 6 1 0 60 Animals|Sheep|Mice|*Scrapie|PrPSc Proteins|*Brain|*Gene Expression Profiling|*Microarray Analysis|Central Nervous System|Genotype|Base Sequence 9 MPLKIP 17310276 Cell. Mol. Life Sci. 2007 10.1007/s00018-007-6501-8 8 2 2 180 Humans|polo-like kinase 1|*Cell Cycle Proteins|*Serine Threonine Kinase|*Proto-Oncogene Proteins|*Cell Cycle|Mitosis|CDC2 Protein Kinase|Cytokinesis|Phosphorylation|Centrosome|Spindle Apparatus|Protein Kinases|*Trichothiodystrophy Syndromes|Serine|HeLa Cells|Protein Binding|Mutation|siRNA 9 plekhh2 17251388 J. Am. Soc. 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Life Sci. 2006 10.1007/s00018-006-6192-6 238 0 16 43 "Humans|DNAJA1 protein, human|DNAJB1 protein, human|*HSP40 Heat-Shock Proteins|*HSP70 Heat-Shock Proteins|DNAJC14 protein, human|*Molecular Chaperones|Heat-Shock Proteins|Escherichia coli Proteins|Escherichia coli|Amino Acid Sequence|Fetal Proteins|DNAJC21 protein, human|DnaJ protein, E coli" 9 LRFN5 16828986 Gene 2006 10.1016/j.gene.2006.05.014 25 2 4 60 9 PAGE2 17160639 J. Mol. Evol. 2006 10.1007/s00239-006-0097-8 3 0 0 8 "*Arabidopsis|*Centromere|Chromosomes, Plant|DNA, Plant|Phylogeny|Evolution, Molecular|Genetic Variation" 9 PAGE2 16636927 Genetica 2006 10.1007/s10709-005-0718-y 2 0 0 8 "*Arabidopsis|In Situ Hybridization, Fluorescence|*Centromere|DNAs, Satellite|Chromosomes, Plant|DNA, Ribosomal|Phylogeny" 9 SAGE1 16929165 Cancer Biol. Ther. 2006 10.4161/cbt.5.9.3174 19 0 0 162 "Humans|Male|*Squamous Cell Carcinoma of Head and Neck|*Testis|MAGEA3 protein, human|Antigens, Neoplasm|Neoplasm Proteins|Head and Neck Neoplasms|Carcinoma, Squamous Cell|*Immunotherapy|Biomarkers, Tumor|Membrane Proteins|BRDT protein, human|Nuclear Proteins|*Immunologic Factors" 9 TSC22D2 17147695 FEBS J. 2006 10.1111/j.1742-4658.2006.05569.x 12 1 0 214 "Animals|Mice|*Osmotic Pressure|*RNA Splicing|*Epithelial Cells|mRNA|Transcription Factors|Alternative Splicing|Gills|Tilapia|Amino Acid Sequence|*Kidney|Transcriptional Activation|Upregulation|*Protective Agents|Kidney Medulla|Cells, Cultured" 9 38047 16155007 J. Biol. Chem. 2005 10.1074/jbc.M502849200 25 0 1 0 "edelfosine|Phospholipid Ethers|*Membrane Microdomains|Saccharomyces cerevisiae|lysophosphatidic acid|*Lysophospholipids|Saccharomyces cerevisiae Proteins|Sphingolipids|Proton-Translocating ATPases|Membrane Lipids|Plasma Membrane|Drugs, Antitumor|*Cancer|Protein Transport|Endocytosis" 9 38047 15887984 Rural Remote Health 2005 2 0 0 0 "Humans|Iran|*System, Healthcare|*Referral|Specialists|Medicine|Health Insurance|Income|Rural Population" 9 ASCL4 16078733 Yi Chuan Xue Bao 2005 0 0 0 5 "Humans|Porokeratosis, disseminated superficial actinic 1|*Porokeratosis|Lod Score|Pedigree|Genetic Linkage|Chromosome Mapping|Haplotype|Mutation|Exons|Microsatellite Repeats|PWP1 protein, human|Nuclear Proteins|Cell Cycle Proteins" 9 FBXO47 15723337 Genes Chromosomes Cancer 2005 10.1002/gcc.20170 5 0 1 76 "Humans|*Carcinoma, Renal Cell|*Cloning, Molecular|Exons|Genes, Tumor Suppressor|Loss of Heterozygosity|Chromosome Mapping|DNA, Neoplasm|Amino Acid Sequence|cDNA|*Chromosome Structures|Microsatellite Markers|Chromosome Deletion|Heterozygote|Kidney Neoplasms" 9 PRDM15 16036106 Neoplasia 2005 PMC1501288 10.1593/neo.04586 75 0 2 26 "Humans|*Comparative Genomic Hybridization|*Homozygote|*Sequence Deletion|*Pancreatic Cancer|cDNA Microarrays|Gene Amplification|In Situ Hybridization, Fluorescence|Oncogenes|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Polymerase Chain Reaction|N33 protein, human|Tumor Suppressor Proteins|*Nucleic Acid Amplification Techniques|Gene Deletion|Chromosomes, Human|cDNA|Membrane Proteins" 9 PRDM15 15904895 Biochem. Biophys. Res. Commun. 2005 10.1016/j.bbrc.2005.04.159 2 0 0 26 "Humans|Zinc Fingers|DNA-Binding Proteins|Transcription Factors|cDNA|Amino Acid Sequence|Sequence Alignment|Base Sequence|Chromosome Mapping|Cloning, Molecular|Blotting, Northern|*Human Chromosome|Exons|RNA, Messenger|Sequence Homology, Amino Acid|DNA|Sequence Analysis, DNA|Cell Line" 9 SLC45A1 15763422 Cell. Signal. 2005 10.1016/j.cellsig.2005.01.004 6 0 0 3 *Acidosis|Hypercapnia|Proto-Oncogene Proteins c-fos|Proto-Oncogene Proteins c-jun|*Brain|Medulla Oblongata|Neurons|Signal Transduction|*Central Nervous System|Gene Expression 9 38047 15274096 Pediatr. Pulmonol. 2004 10.1002/ppul.20080 3 0 0 0 "Child|Humans|Young Adult|Adolescent|*Smoking Habits|*Asthma|Questionnaire|Risk Factors|Military Personnel|Smoking, Tobacco" 9 38047 15218029 J. Biol. Chem. 2004 10.1074/jbc.M404319200 35 7 0 0 *Protein Transport|*Mitochondria|*Carrier Proteins|Mitochondrial Membrane Transport Proteins|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Mitochondrial Proteins|Membrane Transport Proteins|Mitochondrial Membranes|Membrane Proteins|Heat Shock Protein 70|Molecular Motor Proteins|Protein Precursors|Protein Binding|Amino Acid Sequence|*Dyneins|*Kinesin|*Myosins 9 ABCC13 15203202 Genomics 2004 10.1016/j.ygeno.2004.02.010 10 0 0 1 "Humans|Mice|Rats|Animals|Macaca mulatta|*Transporters, ABC|Exons|Introns|cDNA|Sequence Alignment|Amino Acid Sequence|multidrug resistance-associated protein 2|Multidrug Resistance-Associated Proteins|Cloning, Molecular|*Mammals|Open Reading Frame|Chromosome|Sequence Homology, Amino Acid|Pseudogenes|Multigene Family|RNA, Messenger|Genome, Human" 9 ADAM18 14963094 Mol. Biol. Evol. 2004 10.1093/molbev/msh080 10 0 1 1 "Male|Phylogeny|Disintegrins|ADAM Proteins|Amino Acid Sequence|Membrane Glycoproteins|Spermatogenesis|Evolution, Molecular|Fertilins|Membrane Proteins|Testis|Binding Sites|Sperm|*Reproduction|Codon" 9 ASCL4 15475265 Genomics 2004 10.1016/j.ygeno.2004.07.004 7 0 2 5 "Adult|Humans|Helix-Loop-Helix Domain|Transcription Factors|Basic Helix-Loop-Helix Transcription Factors|RNA, Messenger|Amino Acid Sequence|Gene Expression" 9 GPR63 15258916 J. Cell. Biochem. 2004 10.1002/jcb.20092 22 0 1 30 "sphingosine 1-phosphate|sphingosine phosphorylcholine|*Ligands|*Phosphatidic Acid|lysophosphatidic acid|*Lysophospholipids|*Sphingosine|GPR68 protein, human|*Phosphorylcholine|Receptors, Lysophospholipid|Lysophosphatidic Acid Receptor|Receptors, Cell Surface|Signal Transduction|G Protein|Cell Motility|Cell Membrane" 9 GTDC1 15068588 DNA Cell Biol. 2004 10.1089/104454904322964788 5 0 1 65 "Male|Adult|Humans|Animals|Mice|GTDC1 protein, human|*Glycosyltransferases|*Gene Library|Amino Acid Sequence|cDNA|Cloning, Molecular|Sequence Alignment|Base Sequence|Sequence Homology, Amino Acid|Glycoproteins|*Fetus" 9 PAGE2 15586291 Mol. Genet. Genomics 2004 10.1007/s00438-004-1081-x 14 0 1 8 "*Arabidopsis|Phylogeny|*Centromeres|DNA, Satellite|DNA, Plant|Chromosomes, Plant|Repetitive Sequences|*Genomics|Genome, Plant|Evolution, Molecular|Genetic Variation|Species Specificity" 9 SRFBP1 15492011 J. Biol. Chem. 2004 10.1074/jbc.M405945200 17 3 1 99 "Humans|Mice|Animals|*Serum Response Factor|myocardin|Nuclear Proteins|Trans-Activators|*Gene Expression Regulation|Transcription Factor|Homeodomain Proteins|Promoter Regions, Genetic|Binding Sites|Genes, Reporter|Actin|Transfections|Cardiac Muscle|Protein Binding|mRNA|Cell Differentiation|*Hearts" 9 UNC5CL 14769797 J. Biol. Chem. 2004 10.1074/jbc.M310737200 10 9 0 32 "*NF-kappa B|*Death Domain|RELA protein, human|*Transcription Factor RelA|Tumor Necrosis Factor-alpha|TNF-Related Apoptosis-Inducing Ligand|Signal Transduction|Apoptosis|NF-kappa B p50 Subunit|Electrophoretic Mobility Shift Assay|Transfection|Apoptosis Regulatory Proteins|Reporter Gene|Protein Binding|Interleukin 1|Cell Line, Tumor|Membrane Glycoproteins|Transcriptional Activation" 9 ABCC13 12909339 Gene 2003 10.1016/s0378-1119(03)00530-4 6 1 0 1 "Humans|Male|Animals|*Heterochromatin|Phylogeny|Gene Mapping|Pseudogenes|Amino Acid Sequence|Genomics|Sequence Analysis, DNA|Centromere|Exon|Hominidae|Testis|Chromosomes, Human" 9 GPR63 12618218 Cell. 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Genet. 2019 PMC7305813 10.1093/hmg/ddz240 0 0 0 7 "Humans|Mice|Animals|*Stereocilia|*Mice, Inbred C57BL|*Hearing Loss|Inner Hair Cells|Outer Hair Cells|Cochlea|Deafness|Mice, Knockout|GTPase Activating Protein|Actin Cytoskeleton|Mutation|Cytoskeleton|ARL2 protein, human|GTP-Binding Proteins" 8 ELMOD3 30736458 J Clin Med 2019 PMC6406497 10.3390/jcm8020212 0 11 0 7 "Humans|*Autism Spectrum Disorder|*Post-Synaptic Density|DNA Copy Number Variations|Exome|Pedigree|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Sequencing, Whole Exome|Siblings|Case-Control Studies|Sardinia" 8 FAM155A 31099194 J. Korean Med. Sci. 2019 PMC6522894 10.3346/jkms.2019.34.e144 0 1 0 3 "*Carcinoma, Renal Cell|*Progression-Free Survival|Kidney Neoplasms|DNA Methylation|CpG Islands|Epigenesis, Genetic|Prognosis|Promoter Regions, Genetic|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic" 8 FAM155A 30661054 Gut 2019 10.1136/gutjnl-2018-317619 7 0 0 3 "*Genome-Wide Association Study|*Diverticular Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Diverticulitis|Colon|*Connective Tissue" 8 FASTKD1 31268778 "Am. J. Physiol., Cell Physiol." 2019 PMC6766616 10.1152/ajpcell.00471.2018 0 17 0 29 "Mice|Animals|PPID protein, human|*Cyclophilins|*Cyclophilin D|mitochondrial permeability transition pore|Mitochondrial Membrane Transport Proteins|*Cell Death|*Oxidative Stress|Mitochondria|Mitochondrial Swelling|Reactive Oxygen Species|Necrosis|Hydrogen Peroxide|Cells, Cultured|Calcium" 8 FKBP15 30666567 J. Appl. Genet. 2019 10.1007/s13353-019-00483-1 1 0 0 140 "Horses|Animals|*Exome|*Genomics|Breeding|Frequencies, Allele|*Whole Exome Sequencing|SNPs|Genotype|Linkage Disequilibrium|Phenotype|Oligonucleotide Array Sequence Analysis|Running" 8 IGFL2 31727869 Aging (Albany NY) 2019 PMC6874440 10.18632/aging.102407 0 0 0 1 "Humans|Male|Female|United States|*Carcinoma, Renal Cell|*Long Non-Coding RNA|*Prognosis|Cancer, Kidney|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Cell Proliferation|Kaplan-Meier Estimate|Signal Transduction|Cell Line, Tumor|ZNF582 protein, human|Kruppel-Like Transcription Factors" 8 KLHL15 30756084 Biomed Res Int 2019 PMC6348882 10.1155/2019/6305065 3 8 0 347 "*RNA, Long Noncoding|*mRNA|*Transcriptome|*Silica|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|*Pulmonary Fibrosis|Gene Regulatory Networks|Gene Ontology|*Ubiquitination|Signal Transduction" 8 LINC00478 31608179 PeerJ 2019 PMC6786248 10.7717/peerj.7821 1 0 0 1 "*RNA, Long Noncoding|*Transcriptome|Gene Regulatory Networks|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|MicroRNAs|Gene Expression Profiling|RNA, Messenger|Gene Ontology|Kaplan-Meier Estimate|Data Mining" 8 LINC00478 31208318 BMC Genomics 2019 PMC6580620 10.1186/s12864-019-5887-7 5 0 0 1 "*miRNA|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Expression Profiles|Biomarkers, Tumor|RNA, Messenger|Cluster Analysis" 8 LYZL1 31424156 Proteomics Clin Appl 2019 10.1002/prca.201900007 0 0 0 40 "Male|Humans|*Teratozoospermia|*Proteomics|Infertility, Male|Spermatozoa|Acrosome|Membrane Proteins|DPY19L2 protein, human" 8 MYLK4 31667592 Hum. Genet. 2019 10.1007/s00439-019-02079-5 1 0 0 37 "Infant|Humans|*Genome-Wide Association Study|Benin|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Quantitative Trait Loci|*Malaria|Genotype|Phenotype|Malaria, Falciparum|Case-Control Studies|Carrier Proteins" 8 MYLK4 31280665 Anim. Biotechnol. 2019 10.1080/10495398.2019.1635137 0 0 0 37 "Animals|*DNA Copy Number Variations|Genome|Breeding|Goats|Phenotype|Genetic Variation|Polymorphism, Single Nucleotide" 8 MYLK4 31222274 J. Anim. Sci. 2019 PMC6488331 10.1093/jas/skz091 1 0 0 37 "Humans|Swine|Animals|*mRNA|*miRNA|*Transcriptome|*Transcriptome Analysis|Muscle Development|Regulatory Network, Gene|Breeding|Muscle Fibers, Skeletal|Gene Expression Regulation, Developmental|Sus scrofa|*Biological Phenomena|Muscle, Skeletal|*Epigenesis, Genetic|Embryonic Development|Downregulation|Meat|Phenotype" 8 SIDT1 31632087 Onco Targets Ther 2019 PMC6792947 10.2147/OTT.S215898 0 1 0 11 "Humans|*Triple-Negative Breast Cancer|*Prognosis|*Computational Biology|*Data Analysis|Receptor, ErbB-2|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Kaplan-Meier Estimate" 8 SIDT1 31061008 J. Immunol. 2019 10.4049/jimmunol.1801369 0 2 0 11 "*RNA, Double-Stranded|*Lysosomes|*Endosomes|Encephalomyocarditis virus|Cardiovirus Infections|RNA Transport|Nucleotide Transport Proteins|Innate Immune Response|Membrane Proteins|Protein Binding|*RNA, Double-Stranded|*Lysosomes|*Endosomes|Encephalomyocarditis virus|Cardiovirus Infections|RNA Transport|Nucleotide Transport Proteins|Innate Immune Response|Membrane Proteins|Protein Binding" 8 SLC22A10 30755830 PeerJ 2019 PMC6368834 10.7717/peerj.6375 7 1 0 14 "*Carcinoma, Hepatocellular|*Liver Neoplasms|*Computational Biology|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Biomarkers, Tumor|Protein Interaction Maps|Databases, Genetic|Disease Progression" 8 SLC25A45 31612115 Front Oncol 2019 PMC6776930 10.3389/fonc.2019.00996 3 0 0 90 8 SLC38A10 31842320 Int J Mol Sci 2019 PMC6940841 10.3390/ijms20246265 1 0 0 23 "Humans|Mice|Animals|*Golgi Apparatus|Endoplasmic Reticulum|Protein Transport|Biological Transport|SLC38A9 protein, human|Amino Acid Transport Systems|*Protein Biosynthesis|HeLa Cells|RNA, Small Interfering" 8 SLC38A10 31524172 J. 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Dis. 2019 10.1136/annrheumdis-2019-215533 0 0 0 33 "*Autoimmunity|*T-Lymphocytes|*Lupus Erythematosus, Systemic|*Rheumatoid Arthritis|*Autoimmune Diseases|Sjogren's Syndrome|Genetic Predisposition|Genotype|Polymorphism, Single Nucleotide|*Germ Line" 8 VWA8 31702900 Biochemistry 2019 10.1021/acs.biochem.9b00863 1 3 0 33 "Mice|Animals|*Hepatocyte Nuclear Factor 4|*Protein, Mitochondrial|*Hepatocytes|*Oxidative Stress|Livers|Reactive Oxygen Species|Mitochondria|Lipid Metabolism|Mitochondrial Membranes|Diet, High-Fat|Oxidation-Reduction|ATPase|Hydrogen Peroxide|Homeostasis|VWA8 protein, mouse" 8 VWA8 31630795 Biochem. Biophys. Res. 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Oncol. 2018 10.1016/j.ygyno.2018.12.017 6 0 0 5 "Humans|Female|*Human Papilloma Virus|*Uterine Cervical Neoplasms|*Papillomavirus Infections|DNA, Viral|*Genomics|Prognosis" 8 Ankrd7 30289875 Med. Sci. Monit. 2018 PMC6186152 10.12659/MSM.910916 4 3 0 5 "Humans|*Computational Biology|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|Protein Interaction Maps|Gene Ontology|Gene Regulatory Networks|*Leukemia, Myeloid, Acute|Gene Expression Profiling|Databases, Genetic|*Mutations|Protein Interaction Mapping|Transcriptome|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Prognosis|Clustering|Signal Transduction|OTOA protein, human" 8 ARGFX 29423137 Evodevo 2018 PMC5787275 10.1186/s13227-018-0091-4 3 2 0 69 "Mice|Animals|Homeo Box Genes|Gene Duplication|Evolution, Molecular|Multigene Family|Homeodomain Proteins|Embryonic Development" 8 ARMC3 29577858 Curr. Mol. Med. 2018 10.2174/1566524018666180322162145 1 0 0 2 "Male|*Squamous Cell Carcinoma of Head and Neck|*Prognosis|*Testis|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Antigens, Neoplasm|Neoplasm Proteins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Lymphatic Metastasis|Immunotherapy" 8 C10orf107 29625022 Am. J. Hum. Genet. 2018 PMC5985289 10.1016/j.ajhg.2018.02.016 1 0 0 4 "Humans|Retrospective Studies|Prospective Studies|*Phenotype|*Genetic Testing|Pedigree|Quantitative Trait Loci|Genetic Association Studies|Models, Genetic|Genome-Wide Association Study|SNPs|Framingham Heart Study|Trait, Complex|Software|Computer Simulation" 8 C3orf58 29666759 PeerJ 2018 PMC5896498 10.7717/peerj.4599 1 7 0 152 "Humans|Proteomics|HEK293 Cells|Pilot Projects|Chromatography, Liquid|Phosphopeptides|Tandem Mass Spectrometry|Phosphoproteins|Signal Transduction" 8 CSNK1G1 30264502 Genes Chromosomes Cancer 2018 10.1002/gcc.22675 3 0 0 88 "Humans|*HPV 16|NFIX protein, human|*NFI Transcription Factors|Comparative Genomic Hybridization|*Anus Neoplasms|DNA, Viral|Papillomavirus Infections|Virus Integration|Carcinoma, Squamous Cell|Gene Expression|Viral Genome|BCAR3 protein, human|Adaptor Proteins, Signal Transducing" 8 CSNK1G1 29967001 Cancer Epidemiol. 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Genet. 2018 10.1007/s13353-018-0472-3 2 2 0 7 "Male|Humans|*Intellectual Disability|*Autism Spectrum Disorder|*Homozygote|Sequence Deletion|*Hearing Loss|*Deafness|Phenotype|Stereotypic Movement Disorder|DNA Copy Number Variations|Autism|Transcription Factors|CAPG protein, human|Microfilament Proteins|Nuclear Proteins" 8 ELMOD3 29713870 Hum. Genet. 2018 10.1007/s00439-018-1885-0 3 0 0 7 "Humans|Genes, Dominant|Pedigree|Nonsyndromic Deafness|Deafness|*Hearing Loss|Exome|Hearing Loss, Sensorineural|Multiple Pterygium Syndrome, Autosomal Dominant|*Arthrogryposis|Phenotype|Mutation|Chinese|Mutation, Missense|Genotype|High-Throughput Nucleotide Sequencing|Sequencing, Whole Exome|Amino Acid Sequence|Exon" 8 FAM155A 30565714 Int Endod J 2018 10.1111/iej.13060 0 8 0 3 "*Tooth, Supernumerary|*RNA-Seq|*Dental Pulp|Stem Cells|Cell Differentiation|Cells, Cultured|Cell Proliferation|Cell Culture Techniques" 8 FAM50A 30322386 Reprod. Biol. 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Patterns 2018 10.1016/j.gep.2018.04.004 1 0 0 33 "Humans|Mice|Animals|*von Willebrand Protein|Embryo, Mammalian|mRNA|In Situ Hybridization|Gene Expression Regulation, Developmental|Cell Line|Binding Proteins|Gene Expression|VWA8 protein, mouse|Adenosine Triphosphatases" 8 ZDHHC20 30481009 Biochemistry 2018 PMC7266526 10.1021/acs.biochem.8b01070 2 0 0 106 "Humans|Animals|*Membrane Proteins|Green Fluorescent Proteins|Luminescent Proteins|Recombinant Fusion Proteins|Bacterial Proteins|Fluorescence|Recombinant Proteins|HEK293 Cells|Microscopy, Confocal|Size Exclusion Chromatography" 8 ZDHHC20 29884859 Nat Commun 2018 PMC5993824 10.1038/s41467-018-04674-y 3 36 0 106 "Humans|*HIV-1|*Cyclophilin A|*Lipoylation|tat Gene Products, Human Immunodeficiency Virus|Phosphatidylinositol 4,5-Diphosphate|cyclophilin B|*Cyclophilins|Jurkat Cells|Cell Membrane|Phosphatidylinositol|*HIV Seropositivity|Protein Binding" 8 ZDHHC20 29326245 Science 2018 PMC6317078 10.1126/science.aao6326 27 1 0 106 Palmitoylation|Acyl Coenzyme A|Substrate Specificity|Acyltransferases|Active Site|Membrane Proteins|*Membrane|Cysteine 8 37681 28445150 Oncotarget 2017 PMC5514940 10.18632/oncotarget.16949 12 12 0 0 "Humans|*Glioblastoma|Kcnj10 (channel)|Potassium Channels, Inwardly Rectifying|Astrocytes|Neuroglia|Patch-Clamp Techniques|Membrane Potentials|Down-Regulation|Potassium|MicroRNAs|Cells, Cultured|Cell Lines|MIRN-5096 microRNA, human" 8 ACTR3B 29061174 BMC Med. Genet. 2017 PMC5654040 10.1186/s12881-017-0482-8 2 1 0 62 "Child|Humans|*Abnormalities, Multiple|Deletions, Chromosome|Phenotypes|Intellectual Disability|*Failure to Thrive|In Situ Hybridization, Fluorescence|Syndrome|*Chromosome Structures" 8 ANKRD52 28114302 Nature 2017 PMC5302127 10.1038/nature21025 51 26 0 174 "Humans|AGO2 protein, human|*Argonaute Proteins|*RNA, Micro|*Phosphorylation|mRNA|Downregulation|Protein Binding|HEK293 Cells|HeLa Cells" 8 ANKRD52 28052524 Genes Chromosomes Cancer 2017 10.1002/gcc.22441 10 0 0 174 "Humans|Dogs|Animals|*Urinary Bladder Neoplasms|*Transcriptome|*Exome|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor" 8 ARMC10 28849214 Mol Med Rep 2017 PMC5865771 10.3892/mmr.2017.7357 0 0 0 49 "Animals|Humans|*Zebrafish|*Armadillo|Zebrafish Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Embryonic Development|In Situ Hybridization|Amino Acid Sequence|Sequence Alignment|mRNA|Morphogenesis|*Cell Movement|Nervous System|Sequence Homology, Amino Acid|GPRASP2 protein, human|Intracellular Signaling Peptides and Proteins" 8 ASPRV1 29212956 JCI Insight 2017 PMC5752297 10.1172/jci.insight.96882 0 0 0 119 "Animals|Mice|*Encephalomyelitis, Autoimmune, Experimental|*Neutrophils|Myelin-Oligodendrocyte Glycoprotein|*B Cells|ICAM1 protein, human|*Intercellular Adhesion Molecule-1|*Inflammation|Multiple Sclerosis|Antigen Presentation|Spinal Cord|Histocompatibility Antigens Class II|Macrophage|Mice, Inbred C57BL|Myelin|Cytokines|Encephalomyelitis" 8 ASPRV1 28249031 PLoS Genet. 2017 PMC5352138 10.1371/journal.pgen.1006651 0 0 0 119 "Humans|Dogs|Animals|*Ichthyoses|filaggrin|Intermediate Filament Proteins|Ichthyosis Vulgaris|Epidermis|*Ichthyosis, Lamellar|Skin|Keratinocytes|Base Sequence|Protein Precursors|Mutation, Missense" 8 C10orf107 29258278 Int J Environ Res Public Health 2017 PMC5751013 10.3390/ijerph14121596 2 5 0 4 "Humans|*Blood Pressure|High Blood Pressure|*Cohort Studies|Blood Pressure Determination|European Continental Ancestry Group|African Americans|Socioeconomic Factor|Gene-Environment Interaction|Genetic Susceptibility|Longitudinal Studies|Systole|Risk Factors|Polymorphism, Single Nucleotide" 8 C15orf48 29271998 Eur Rev Med Pharmacol Sci 2017 10.26355/eurrev_201712_14008 2 0 0 121 "*Long Non-Coding RNA|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|RNA, Messenger" 8 C3orf58 28096202 Biochem. J. 2017 10.1042/BCJ20160976 3 6 0 152 "*Insulin-Like Growth Factor I|*Receptor, IGF Type 1|IGF1R protein, human|*Receptors, Somatomedin|Cell Signaling|Cardiomyocytes|Mitogen-Activated Protein Kinase 3|Mitogen-Activated Protein Kinase 1|Phosphorylation|INSR protein, human|Insulin Receptor|Proto-Oncogene Proteins c-akt|IGF2R protein, human|Receptor, IGF Type 2|siRNA|Cell Proliferation|Heart Ventricles|*Ligands" 8 CGB2 29058301 Pathol. Oncol. Res. 2017 10.1007/s12253-017-0313-4 7 0 0 15 "Humans|Male|*Carcinoma, Transitional Cell|*Urinary Bladder|*Testis|Urinary Bladder Neoplasms|MAGEA3 protein, human|Neoplasm Proteins|Antigens, Neoplasm|Biomarkers, Tumor|mRNA|ACTL7A protein, human|Actins|TSGA10 protein, human|Proteins|PIWIL2 protein, human|Argonaute Proteins" 8 DHRS12 28475762 Hum. Mol. 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Chem. 2017 PMC5314175 10.1074/jbc.M116.758235 12 10 0 73 "*Endonucleases|EXO1 protein, human|Exodeoxyribonucleases|DNA Replication|DNA Repair|Genome Instability|Endodeoxyribonucleases|Homologous Recombination|DNA Repair Enzymes|DNA Breaks, Double-Stranded|Recombination Repair, Homologous|DNA Helicases|*Chromosome Structures" 8 ELMOD1 29222402 J. Neurosci. 2017 PMC5783965 10.1523/JNEUROSCI.2658-17.2017 4 1 0 33 "Humans|Mice|Animals|*Hydrolysis|*Hair Cells, Vestibular|ADP-Ribosylation Factor|GTPase-Activating Proteins|Cytoskeleton|Protein Transport|Cell Membrane|Actins|Hair Cells, Auditory|Cell Movement|HeLa Cells|Guanosine Triphosphate" 8 FAM155A 28585551 Nat Commun 2017 PMC5467205 10.1038/ncomms15789 9 2 0 3 "*Diverticular Disease|Myasthenic Syndromes, Congenital|*Diverticulitis|Genome-Wide Association Study|Muscle Proteins|Acetylcholinesterase|Mutation|Collagen|Iceland" 8 FAM50A 28574578 J. Cell. 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Immunol. 2016 10.1016/j.jri.2016.11.001 0 0 0 40 Male|Rats|Animals|*Muramidase|*Sperm|Acrosome Reaction|*Fertility|Epididymis|*Immunizations|Sperm Capacitation|Sperm-Ovum Interactions|Testis|*Vaccination|Amino Acid Sequence|Reproduction 8 LYZL1 27611690 PLoS ONE 2016 PMC5017655 10.1371/journal.pone.0161909 1 2 1 40 "Male|Rats|Animals|*Muramidase|Epididymis|Testis|Spermatozoa|Amino Acid Sequence|Genitalia, Male|*In Silico" 8 SEC31B 27634427 Plant Physiol. 2016 PMC5100771 10.1104/pp.16.00967 4 0 0 21 "Arabidopsis|Arabidopsis Proteins|Pollen|Pollen Tube|Gene Expression Regulation, Plant|Germination|Gametogenesis, Plant|Cell Wall|Plants, Genetically Modified|Protein Transport|Endoplasmic Reticulum|Seed|Phenotype" 8 SH3BGRL2 27233781 Dev. 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Res. 2016 PMC5112111 10.1038/pr.2016.152 2 6 1 90 "Humans|Female|Infant, Newborn|Pregnancy|*Premature Birth|*Genome|*Genomics|Inbreeding|Homozygote|Polymorphism, Single Nucleotide|Phenotype" 8 SLC25A45 26901498 PLoS ONE 2016 PMC4763188 10.1371/journal.pone.0145082 2 2 1 90 Animals|Swine|*Genome-Wide Association Study|Quantitative Trait Loci|Genotype|Phenotype|SNPs|Meat|Red Meat|Genomics|Mutations 8 SNORD43 27939727 Clin. Biochem. 2016 10.1016/j.clinbiochem.2016.11.034 10 2 0 0 "*Prognosis|*Colorectal Neoplasms|*Adenocarcinoma|miRNAs|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Neoplasm Recurrence, Local|Lymphatic Metastasis|Up-Regulation|Cell Proliferation|Real-Time Polymerase Chain Reaction|Cell Cycle Control|Apoptosis" 8 SNORD43 27930363 Clin. Chem. Lab. Med. 2016 10.1515/cclm-2016-0756 7 0 0 0 "Adult|Humans|Neoplasm Recurrence, Local|*Colorectal Neoplasms|*MicroRNAs|*Adenocarcinoma|Prognosis|*Upregulation|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Transcriptional Activation|Kaplan-Meier Estimate|Real-Time Polymerase Chain Reaction|*Chronic Disease|*Relapse|MIRN16 microRNA, human" 8 ZDHHC20 27153536 Mol. Cell 2016 PMC4860254 10.1016/j.molcel.2016.04.003 26 34 0 106 "Humans|*Lipoylation|*Signal Transduction|Protein Kinase Inhibitors|ErbB Receptors|Quinazolines|Antineoplastic Agents|Gefitinib|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|Proto-Oncogene Proteins c-akt|Cell Migration|Mutation|EGFR protein, human" 8 AARSD1 25961023 Biomed Res Int 2015 PMC4413250 10.1155/2015/492395 12 9 1 87 "Humans|*Exosomes|*HIV-1|*mRNA|*Transcriptome|nef protein, Human immunodeficiency virus 1|*nef Gene Products, Human Immunodeficiency Virus|HIV Infections|CD4-Positive T-Lymphocytes|*Monocytes|Virus Replication|U937 Cells|MicroRNAs|*Transcriptome Analysis|Cell Communication|Signal Transduction|nef protein, Human immunodeficiency virus 2" 8 ARGFX 26360614 Nat Commun 2015 PMC4569847 10.1038/ncomms9207 29 0 7 69 "Humans|*Transcription Factors|*Retroelements|Embryonic Development|Blastocyst|Zygotes|Oocytes|Homeo Box Genes|Homeodomain Proteins|Blastomeres|Gene Expression Regulation, Developmental|Pluripotent Stem Cells|RNA, Messenger|Base Sequence|LEUTX protein, human" 8 ASPRV1 25739514 Exp. Dermatol. 2015 PMC4437054 10.1111/exd.12681 0 1 0 119 Animals|*Caspase 14|*Dolphins|filaggrin|*Intermediate Filament Proteins|Whales|*Comparative Genomics|Epidermis|Amino Acid Sequence|Keratinocytes|Phylogeny|PCR 8 C15orf48 25556502 Asian Pac. J. Cancer Prev. 2015 10.7314/apjcp.2014.15.23.10513 12 0 3 121 "Humans|*Long Non-Coding RNA|*Carcinoma, Hepatocellular|*Liver Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Gene Regulatory Networks|Gene Ontology|RNA, Messenger|*Cell Line" 8 CGB2 25570081 Conf Proc IEEE Eng Med Biol Soc 2015 10.1109/EMBC.2014.6943713 2 3 1 15 "Male|*Bayes Theorem|ABCG1 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 1|ATP Binding Cassette Transporter 1|Orphan Nuclear Receptors|Liver X Receptors|*Gene Expressions|ATP-Binding Cassette Transporters|Cholesterol|Macrophages|Hybrid-B|*Plasminogen Activators|Signal Transduction|RNA, Messenger|*Hypertension" 8 CSNK1G1 26428916 Pharm Biol 2015 10.3109/13880209.2015.1071414 6 0 0 88 "3,4,5,4'-tetramethoxystilbene|*Endothelial Cells|*Stilbenes|Resveratrol|Apoptosis|Cell Line, Tumor|Effects, Antiangiogenesis|*Gene Expression Profiling|DMU-212|*Microarray Analysis|*Cell Death" 8 DHRS12 26475974 Eur J Med Genet 2015 10.1016/j.ejmg.2015.10.006 2 0 0 2 "Humans|Macrocephaly|Chromosome Deletion|Intellectual Disability|Comparative Genomic Hybridization|Phenotypes|In Situ Hybridization, Fluorescence|*Chromosome Structures" 8 DHRS12 26332579 PLoS ONE 2015 PMC4558091 10.1371/journal.pone.0137145 10 1 2 2 Animals|Female|*Genome-Wide Association Study|*Chickens|*Ovary|Phenotype|Quantitative Trait Loci|*Body Weight|Breeding|Eggs|Single Nucleotide Polymorphism|Egg Yolk|Genotype|Oviposition|Ovarian Follicle|*Cytoplasm 8 DNAH12 25731871 Gut 2015 10.1136/gutjnl-2014-308617 29 0 4 10 "*Crohn Disease|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Nod2 Signaling Adaptor Protein|Case-Control Studies|*DNA" 8 EEPD1 26684013 PLoS Genet. 2015 PMC4684289 10.1371/journal.pgen.1005675 23 61 2 73 "*Recombinational DNA Repair|exodeoxyribonuclease I|*Exodeoxyribonucleases|EXO1 protein, human|*DNA Repair|*Stability, Genome|*DNA Repair Enzymes|DNA End-Joining Repair|TP53BP1 protein, human|Tumor Suppressor p53-Binding Protein 1|Homologous Recombination|DNA Replication|*Endonucleases|DNA Breaks, Double-Stranded|Endodeoxyribonucleases|*Phosphoric Monoester Hydrolases|DNA-Binding Proteins" 8 ELMOD1 25849460 J. Proteome Res. 2015 10.1021/pr501039k 3 0 0 33 "Mice|Animals|*Knockout Mouse|*Metabolomics|*NMR Spectroscopy|*Magnetic Resonance Imaging|Metabolome|*Plasma|Proton Magnetic Resonance Spectroscopy|Liver|Triglycerides|Lipids|Out, Gene Knock|*Phenotypes|Emc10 protein, mouse|Membrane Proteins" 8 FAM155A 25963547 Cancer 2015 PMC4641835 10.1002/cncr.29153 12 0 1 3 Adult|Humans|Child|*Neoplasms|*Survivors|*Cohort Studies|*Obesity|Childhood Cancer Survivors|Risk Factors 8 FAM50A 26390436 PLoS ONE 2015 PMC4577125 10.1371/journal.pone.0138524 8 3 2 21 "*Transcriptome|*Epigenomics|Networks, Gene|miRNA|Computational Biology|Gene Expression Profiling|mRNA|Bone Mineral Density|Osteoporosis|Databases, Genetic|Microarray Analysis|Signal Transduction" 8 FASTKD1 26001296 Oncotarget 2015 PMC4599287 10.18632/oncotarget.4113 12 2 1 29 "Child|Humans|Adult|*Transcriptome|Acute Lymphoblastic Leukemia|Fusion Proteins, bcr-abl|Prognosis|Translocation, Genetic|Gene Expression Profiling" 8 GPR62 26384023 PLoS ONE 2015 PMC4575141 10.1371/journal.pone.0138463 28 4 1 16 "Animals|Cricetinae|CHO Cells|Cricetulus|GPR68 protein, human|*G-Protein-Coupled Receptors|ADGRG1 protein, human|GPR15 protein, human|GPR39 protein, human|GPR32 protein, human|GPR17 protein, human|Receptors, Peptide|Forskolin|Cyclic AMP|Signal Transduction|Gene Expression|Reporter Gene" 8 KIAA0100 26338045 J. 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Dis. 2015 10.1016/j.bcmd.2015.01.004 8 0 4 0 "Humans|*MicroRNAs|*Leukocytes|Quantitative Real Time PCR|Gene Expression Regulation|Gene Expression Profiling|Reference Standards|Gene Expression|Circadian Rhythms|MIRN16 microRNA, human" 8 SH3BGRL2 26112879 J Nutrigenet Nutrigenomics 2015 10.1159/000431151 7 0 0 11 "*Genome-Wide Association Study|Lipoproteins, LDL|Dietary Fats|Triglycerides|Single Nucleotide Polymorphisms|Quantitative Trait Loci|Particle Size|Quebec" 8 SIDT1 26067272 J. Biol. Chem. 2015 PMC4521010 10.1074/jbc.M115.658864 9 0 0 11 8 SLC25A45 26091520 PLoS ONE 2015 PMC4474865 10.1371/journal.pone.0128106 8 7 0 90 "Humans|Female|*Carcinoma, Ovarian Epithelial|*Ovarian Neoplasms|Neoplasms, Glandular and Epithelial|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Genotype|Case-Control Studies|Risk Factors" 8 TMC5 26380766 J Thorac Dis 2015 PMC4561256 10.3978/j.issn.2072-1439.2015.07.25 15 0 0 25 "*Lung Adenocarcinoma|*Squamous Cell Carcinoma|Lung Cancer|Carcinoma, Non-Small-Cell Lung|Adenocarcinoma|Gene Expression Regulation, Neoplastic|*Biomarkers" 8 WRAP73 26675238 J. Cell. Sci. 2015 10.1242/jcs.179713 11 5 2 97 "*Centrioles|CNTRL protein, human|*Cell Cycle Proteins|Cilia|Axoneme|Microtubule-Associated Proteins|Microtubules|Phosphoproteins|Cell Line|*Cytoplasmic Vesicles|*Cytoplasmic Granules" 8 WRAP73 26545777 Biochem. Biophys. Res. Commun. 2015 PMC4669408 10.1016/j.bbrc.2015.10.169 6 11 2 97 "Humans|*Centrosome|Centrioles|Microtubules|Spindle Apparatus|Microtubule-Associated Proteins|Yeast, Fission|Mitosis|Cell Cycle Proteins|Nuclear Proteins|*Orientation, Spatial|SSX2IP protein, human" 8 ARMC10 24722288 Cell Death Dis 2014 PMC5424104 10.1038/cddis.2014.121 8 6 3 49 Animals|*Mitochondrial Dynamics|Mitochondria|Armadillo Domain Proteins|Neurons|Protein Transport|Nerve Tissue Proteins|Protein Binding|Gene Cluster|mRNA 8 ARMC3 24467795 Mol Autism 2014 PMC3905921 10.1186/2040-2392-5-4 18 0 4 2 Male|Adult|Humans|Female|*Proteomics|*Asperger Syndrome|*Lipid Metabolism|*Sex Differences|*Serum|*Inflammation|Immunoassay 8 C10orf107 25071866 Mol Cytogenet 2014 PMC4113123 10.1186/1755-8166-7-47 1 1 0 4 "Humans|Female|Middle Aged|*Translocation, Genetic|*Leukemia, Myeloid, Acute|Proto-Oncogenes|MDS1 and EVI1 Complex Locus Protein|DNA-Binding Proteins|Transcription Factors|Karyotyping|Chromosome Breakpoint|In Situ Hybridization, Fluorescence" 8 C10orf107 24633201 Int J Mol Sci 2014 PMC3975409 10.3390/ijms15034481 0 10 0 4 "Female|Animals|Cattle|*Follicular Fluid|*Proteomics|*Diestrus|Two Dimensional Gel Electrophoresis|Ovarian Follicle|Proteome|Ovary|Progesterone|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Oocytes|Estradiol" 8 C15orf48 25041445 Int. J. Dermatol. 2014 10.1111/ijd.12476 1 0 0 121 "*Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Regulatory Networks|Psoriasis|*Gene Expression|Gene Expression Regulation, Neoplastic" 8 CAPSL 24552271 Cogn Emot 2014 10.1080/02699931.2014.887000 1 0 0 1 "Repression, Psychology|*Memory|Mental Recall|Emotion|Misinformation" 8 CGB2 24778026 Anticancer Res. 2014 3 0 0 15 "Humans|Female|Pregnancy|*Chorionic Gonadotropin, beta Subunit, Human|Placenta|Transcription, Genetic|RNA, Messenger|*Biochemical Phenomena|Cancer|Cell Line" 8 CSNK1G1 24463883 Hum. Mol. Genet. 2014 PMC4030775 10.1093/hmg/ddu030 78 3 8 88 "Humans|*Epilepsy|Infantile Epileptic-Dyskinetic Encephalopathy|Spasms, Infantile|NAV1.2 Voltage-Gated Sodium Channel|KCNQ2 Potassium Channel|Syndromic Epilepsy|Mutation|Potassium Channel|*Sequencing, Whole Genome|Seizure|Phenotypes|Nerve Tissue Proteins" 8 DNAH12 25412847 Mod. Pathol. 2014 10.1038/modpathol.2014.150 14 0 1 10 "Male|Female|*Axonemal Dyneins|*Proto-Oncogene Proteins B-raf|*Cilia|*Epitopes|Immunohistochemistry|Craniopharyngiomas|Mutations|Antibodies, Monoclonal|Biomarkers, Tumor|Rathke Cleft Cysts|*Cross Reactions|Diagnosis, Differential|Pituitary Neoplasms|*Staining" 8 DNAH12 25344116 Mol. Cancer 2014 PMC4219121 10.1186/1476-4598-13-241 6 0 2 10 "Humans|Female|*Prognosis|Ovarian Cancer|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|MicroRNAs|Databases, Genetic|Neoplasm Grading|RNA, Messenger" 8 ELMOD1 24616099 J. Biol. Chem. 2014 PMC4036250 10.1074/jbc.M114.548529 24 1 0 33 "Animals|Humans|*GTPase-Activating Proteins|HEK293 Cells|ADP-Ribosylation Factors|Cytoskeletal Proteins|*Cell Movement|Protein Transport|ARL2 protein, human|GTP-Binding Proteins|ELMOD2 protein, human" 8 ELMOD1 24523945 PLoS ONE 2014 PMC3921226 10.1371/journal.pone.0088889 36 0 5 33 "Genomics|Databases, Genetic|Computational Biology|Genome|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Regulatory Networks|*Phenotype|*Brain|RNA, Messenger|Neuroscience" 8 ELMOD3 24616099 J. Biol. Chem. 2014 PMC4036250 10.1074/jbc.M114.548529 24 1 0 7 "Animals|Humans|*GTPase-Activating Proteins|HEK293 Cells|ADP-Ribosylation Factors|Cytoskeletal Proteins|*Cell Movement|Protein Transport|ARL2 protein, human|GTP-Binding Proteins|ELMOD2 protein, human" 8 FASTKD1 25409762 BMC Cancer 2014 PMC4256816 10.1186/1471-2407-14-852 4 20 0 29 "Humans|Male|*Serine Threonine Kinase|*Apoptosis|*Prostate Cancer|*Prostate|Nuclear Proteins|DNA-Binding Proteins|Cell Line, Tumor|Transcription Factors|Receptors, Androgen|Androgens|Phosphorylation|Gene Expression Regulation, Neoplastic|FASTKD2 protein, human" 8 GNL2 25452588 EMBO Rep. 2014 PMC4304730 10.15252/embr.201439183 10 21 3 87 "Animals|Humans|*Nonsense Mediated mRNA Decay|Drosophila melanogaster|Caenorhabditis elegans|Caenorhabditis elegans Proteins|mRNA|Termination Codons, Premature|RNAi|*Mammals|Drosophila|Carrier Proteins" 8 KIAA0100 24489812 PLoS ONE 2014 PMC3904964 10.1371/journal.pone.0086952 7 1 2 65 "Humans|Carcinoma, Ductal, Breast|ERBB2 protein, human|Receptor, ErbB-2|Prognosis|Immunohistochemistry|Neoplasm Proteins|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Triple-Negative Breast Cancer|Antigens, Neoplasm|mRNA|Kaplan-Meier Estimate|Cytoplasm" 8 KLHL15 24817631 Am. J. Med. Genet. A 2014 10.1002/ajmg.a.36602 4 0 1 347 "Child|Male|Humans|*Array Comparative Genomic Hybridization|Autism Spectrum Disorder|*X-Linked Inheritance|DNA Copy Number Variations|X Chromosome, Human|Intellectual Disability|X Chromosome Inactivation|Genome, Human|Pedigree|Methyl-CpG-Binding Protein 2|Exon|Epilepsy|Mutations|TRPC Cation Channels|TRPC5 protein, human|FMR1 protein, human|Fragile X Mental Retardation Protein|KLHL15 protein, human" 8 LINC00478 25388283 Cancer Res. 2014 PMC4297564 10.1158/0008-5472.CAN-14-1041 30 13 5 1 "Humans|*Prognosis|Receptors, Estrogen|*Estrogens|Receptor, ErbB-2|miRNAs|*Signal Transduction|MCF7 Cells|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|RNA, Long Noncoding|Cell Line, Tumor" 8 LINC00478 24637061 Mol. Cancer Res. 2014 10.1158/1541-7786.MCR-13-0410 5 2 0 1 "Leukemia, Promyelocytic, Acute|Retinoic Acid|*Promoter Regions, Genetic|Leukemia, Myeloid, Acute|RNA, Micro|Oncogene Proteins, Fusion|Chromatin|Epigenesis, Genetic|Cell Differentiation" 8 LRRC17 25102227 Mol. Cell. Endocrinol. 2014 10.1016/j.mce.2014.07.011 11 0 0 9 "Humans|Adipocytes, White|Adipocytes, Brown|*Progenitor Cells|*Adipose Tissue, Subcutaneous|Adipogenesis|Cell Differentiation|Adipose Tissue|Genes, cdc|ADH1B protein, human|Alcohol Dehydrogenase" 8 MYLK4 24709777 Lab. Invest. 2014 10.1038/labinvest.2014.54 15 0 1 37 "Humans|*Myocytes, Cardiac|*Heart Failure|Cardiomyopathy, Dilated|Myocardial Ischemia|Sequencing, RNA|Heart Ventricles|Cardiac Transplantation|Gene Expression Profiling|Transcriptome|mRNA|Upregulation|Downregulation" 8 MYLK4 24663154 J. Anim. Sci. 2014 10.2527/jas.2013-7059 13 0 2 37 "Swine|Female|Animals|Italy|*Genome-Wide Association Study|Genotype|Sus scrofa|Breeding|Genome|Phenotype|Polymorphism, Single Nucleotide|Chromosomes|IGF2 protein, human|IGF-2" 8 RNU6-2 25203915 Forensic Sci Int Genet 2014 10.1016/j.fsigen.2014.08.005 8 0 1 0 "*RNA, Micro|*Real-Time Polymerase Chain Reaction|Forensic Genetics|Messenger RNA|Gene Expression Profiling|Body Fluids|Standardization|Saliva|Skin|Semen" 8 RNU6-2 24573468 Thromb. Haemost. 2014 10.1160/TH13-11-0977 22 0 1 0 "Male|Female|*RNA, Micro|*Cell-Derived Microparticles|*Plasma|Platelets|*Smoking|*Tobacco Smoking|Leukocytes|Biomarkers|Endothelial Cells|Atherosclerosis" 8 RNU6-2 24535468 Endocrine 2014 10.1007/s12020-014-0202-5 7 0 1 0 "*miRNA|Gastro-enteropancreatic neuroendocrine tumor|*Neuroendocrine Tumors|Pancreatic Neoplasms|Intestinal Neoplasms|Ileal Neoplasms|Stomach Neoplasms|Biomarkers, Tumor|*Pancreas|Gene Expression Profiling|*Ileum|Real Time PCR|Downregulation" 8 SEC31B 24627485 J. Biol. Chem. 2014 PMC4002104 10.1074/jbc.M114.547190 10 0 0 21 "Animals|*Nuclear Pore|*Cell Survival|Zebrafish Proteins|COP-Coated Vesicles|Nuclear Pore Complex Proteins|Zebrafish|Gene Knockdown|Endoplasmic Reticulum|Golgi Apparatus|Vesicular Transport Proteins|Organogenesis|mRNA|Gene Expression Regulation, Developmental|Digestive System|NUP107 protein, zebrafish" 8 SLC25A45 25082825 Hum. Mol. Genet. 2014 10.1093/hmg/ddu399 21 1 4 90 Humans|Adult|Middle Aged|*Creatinine|*Chronic Kidney Disease|Glomerular Filtration Rate|Single Nucleotide Polymorphisms|Genome-Wide Association Study|Genetic Predisposition to Disease|Genotype|Allele Frequency|Case-Control Studies|*Mutations|Iceland 8 SNORD43 24792917 Forensic Sci Int Genet 2014 10.1016/j.fsigen.2014.03.011 3 0 0 0 "Female|*Real-Time Polymerase Chain Reaction|*Body Fluids|Saliva|Forensic Genetics|RNA, Micro|Semen|Cervix Mucus|Menstruation|*Diagnostic Tests, Routine" 8 SNORD43 24510997 Anticancer Res. 2014 18 0 0 0 "Humans|Male|*MicroRNAs|*Prostate|*Prospective Studies|Prostate Cancer|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|*Biopsy" 8 VWA8 24378410 J. Clin. 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Biol. 2013 10.1007/978-1-4614-7411-1_43 4 0 0 10 Animals|Rats|Mice|*Glucose|*Ketones|Ketone Bodies|Ketogenic Diet|Ketosis|Oxidation-Reduction|*Cell Respiration|Oxidative Phosphorylation|Energy Expenditure|Glycolysis|Mitochondria|Brain|Oxidative Stress 8 SH3BGRL2 23921681 Int J Mol Sci 2013 PMC3759901 10.3390/ijms140816087 31 14 6 11 "Humans|*Interferon-beta|*Multiple Sclerosis|Leukocytes, Mononuclear|Longitudinal Studies|Multiple Sclerosis, Relapsing-Remitting|MicroRNAs|Gene Expression Regulation|Downregulation|mRNA|Up-Regulation|Leukocytes" 8 SH3BGRL2 23657602 Mol. Biol. 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Cancer Prev. 2013 14 0 0 25 "Humans|Cricetinae|Animals|*Bile Ducts, Intrahepatic|*Intrahepatic Cholangiocarcinoma|Opisthorchis viverrini|Opisthorchiasis|Bile Duct Neoplasms|*Gene Expression Profiling|*Microarray Analysis|Mesocricetus|Gene Expression Regulation, Neoplastic|Fluke, Liver|*Liver Neoplasms|Thailand|GPRC5A protein, human|Receptors, G-Protein-Coupled|MUC13 protein, human|Mucins" 8 AARSD1 23185754 Zhongguo Zhong Xi Yi Jie He Za Zhi 2012 4 0 0 87 "Humans|*Gastritis, Atrophic|*Syndrome|Gastritis|Medicine, Chinese Traditional|Oligonucleotide Array Sequence Analysis|*Energy Metabolism|Gastric Mucosa|*Mucositis|Gene Expression|*Precancerous Conditions|*Musculoskeletal Diseases|Case-Control Studies" 8 Ankrd7 22613542 Chin. Med. J. 2012 PMC4174677 10 2 0 5 "Humans|Genome-Wide Association Study|Alcohol Dependence|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Alcohol Drinking|Phenotype|European Continental Ancestry Group|Alleles|CYTL1 protein, human|Blood Proteins|Cytokines" 8 ARMC10 22569362 Nat Commun 2012 10.1038/ncomms1829 23 3 5 49 "Animals|*Mammals, Eutherian|*Mitochondria|Mitochondrial Proteins|*Neurons|Mitochondrial Dynamics|Carrier Proteins|Kinesin|Intracellular Signaling Peptides and Proteins|rho GTP-Binding Proteins|Hippocampus|*Protein Transport|*Cell Movement" 8 C10orf107 23133444 Exp Diabetes Res 2012 PMC3485973 10.1155/2012/827172 7 5 0 4 "Humans|*Vascular Stiffness|*Steroid 17-alpha-Hydroxylase|Hypertension|Antihypertensive Agents|Blood Pressure|SNPs|Prediabetic State|Cardiovascular Diseases|Genetic Predisposition to Disease|Asian Continental Ancestry Group|*Diabetes Mellitus|Risk Factors|GRK4 protein, human|G-Protein-Coupled Receptor Kinase 4|CYP17A1 protein, human" 8 CAPSL 22654555 Curr. Genomics 2012 PMC3271308 10.2174/138920211798120772 12 36 2 1 "*Graves Disease|PTPN22 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 22|CTLA4 protein, human|CTLA-4 Antigen|Receptors, Thyrotropin|Genetic Predisposition to Disease|Genotype-Phenotype Correlations|Gene Frequency|Genotype|Polymorphism, Genetic|HLA-DPB1 antigen|HLA-DP beta-Chains" 8 DHDH 23028369 PLoS Genet. 2012 PMC3459979 10.1371/journal.pgen.1002962 35 1 7 8 "Humans|Animals|Rats|Guinea Pigs|Rabbits|*Domestication|*Animals, Wild|Domesticated Animals|Selection, Genetic|Breeding|Wolves|Phenotype|*Gene Expression|Genome|Aggression|*Brain" 8 ELMOD1 23014990 J. Biol. Chem. 2012 PMC3501052 10.1074/jbc.M112.417477 28 0 0 33 Humans|*GTPase Activating Protein|Phylogeny|ADP-Ribosylation Factors|Guanine Nucleotide Exchange Factors|Amino Acid Sequence|Sequence Alignments|Conserved Sequence|Eukaryotes|*Biological Evolution|Protein Transport|Fungi|Golgi Apparatus|Protein Domain 8 ELMOD1 22558334 PLoS ONE 2012 PMC3338648 10.1371/journal.pone.0036074 19 0 2 33 "Mice|Animals|*Stereocilia|*Actin Cytoskeleton|Hair Cells, Vestibular|*Mutations|Inner Hair Cell|Actin|*Signal Transduction|GTPase-Activating Proteins|Hearing|Cytoskeleton|Cytoskeletal Proteins|Hair Cells, Auditory, Outer|Deafness|Ear|Small G-Proteins" 8 FAM50A 23181716 Diagn Pathol 2012 PMC3533517 10.1186/1746-1596-7-161 6 3 1 21 "Humans|*Autoantigens|*Carcinoma, Ductal, Breast|Carcinoma, Lobular|Immunohistochemistry|Biomarkers, Tumor|Carcinoma, Medullary|Antigens, Neoplasm|*Carcinomas, Breast" 8 KLHL15 23135275 J. Biol. Chem. 2012 PMC3527925 10.1074/jbc.M112.420281 15 5 2 347 *Protein Phosphatase 2|*E3 Ubiquitin Ligase|Proteomics|Ubiquitylation|Cullin Proteins|Proteasome Endopeptidase Complex|Proteolysis|Signal Transduction|Tyrosine Hydroxylase|*Biochemical Phenomena 8 LRRC17 22682620 Cancer Genet 2012 10.1016/j.cancergen.2012.03.001 28 0 3 9 "*Osteosarcoma|MicroRNAs|*Up-Regulation|*Oncogenes|Bone Neoplasms|Gene Expression Regulation, Neoplastic|*Oncogenesis|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|*Transcriptional Activation|Cell Line, Tumor|Genes, cdc|*Gene Expression|Apoptosis|Cell Cycle Control|Osteoblasts" 8 MAP10 22879057 Adv. Exp. Med. Biol. 2012 10.1007/978-1-4614-4989-8_51 6 0 2 10 "Animals|Rats|*Ketone Bodies|*Glucose|Gas Chromatography-Mass Spectrometry|acetoacetic acid|Acetoacetates|Ketosis|*Brain|Acetyl-CoA|*Cell Respiration|Diet, Ketogenic|Oxidation-Reduction|Oxidative Stress" 8 MYLK4 23064046 Gene 2012 10.1016/j.gene.2012.10.001 6 0 1 37 "Humans|*Alleles|Allelic Imbalance|*Colorectal Cancer|SNPs|Genotype|Gene Expression|Gene Expression Profiling|Exons|*Colonic Neoplasms|Cell Lines|ERAP2 protein, human|Aminopeptidases" 8 PPP1R1C 22929023 Eur. J. Hum. Genet. 2012 PMC3548268 10.1038/ejhg.2012.155 18 0 2 53 "Child|Humans|*DNA Copy Number Variations|Schmid-Fraccaro syndrome|Chromosome Disorders|Genome-Wide Association Study|Aneuploidy|*Cardiovascular Abnormalities|Abnormalities, Multiple|Oligonucleotide Array Sequence Analysis|Eye Abnormalities|Polymorphism, Single Nucleotide|Case-Control Studies|Cohort Studies|Chromosomes, Human, Pair 22|SOX7 protein, human|SOXF Transcription Factors" 8 RNU6-2 22788411 Int. J. 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Cell Biol. 2011 10.1038/ncb2389 23 0 2 87 "*Arabidopsis|Arabidopsis Proteins|*Guanine Nucleotide Exchange Factors|*Endosomes|Indoleacetic Acids|Brefeldin A|Protein Transport|ADP-Ribosylation Factors|Plant Roots|Biological Transport|Membrane Transport Proteins|Cell Membrane|Phenotype|*Morphogenesis|GBF1 protein, Arabidopsis|Transcription Factors" 8 GNL2 21565180 Dev. Biol. 2011 10.1016/j.ydbio.2011.04.028 11 1 1 87 "Animals|*Zebrafish|*Neurogenesis|*Retina|Zebrafish Proteins|Cell Cycle|Cell Differentiation|*GTP-Binding Proteins|Cell Division|Apoptosis|Gene Expression Regulation, Developmental|Cell Proliferation|Stem Cells|Signal Transduction|Cyclin-Dependent Kinase Inhibitor p57|Bromodeoxyuridine|Tumor Suppressor Protein p53|Carrier Proteins|Guanosine Triphosphate" 8 IGFL2 21440540 Exp. 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Genet. 2011 PMC3196886 10.1093/hmg/ddr363 41 0 2 23 "Male|*DNA Copy Number Variations|Comparative Genomic Hybridization|*Autistic Disorder|*Exons|*Genome|Oligonucleotide Array|Genomics|Disorder, Neurodevelopmental" 8 SPRR4 22142393 Exp. Dermatol. 2011 10.1111/j.1600-0625.2011.01417.x 5 0 1 3 "Humans|*Dermatitis, Atopic|pimecrolimus|*Tacrolimus|*Eczema|filaggrin|Intermediate Filament Proteins|Skin|Dermatologic Agents|Epidermis|Administration, Cutaneous|*Skin Diseases|loricrin|Membrane Proteins|Anti-Inflammatory Agents" 8 SPRR4 21673710 J. Invest. Dermatol. 2011 10.1038/jid.2011.119 4 0 0 3 Humans|*Reactive Oxygen Species|Epidermal Cells|Epidermis|Cornified Envelope Proline-Rich Proteins|Keratinocytes|Skin|Proteins|*Cell Membrane|UV Radiation|Cell Differentiation 8 SPRR4 21248766 J. Invest. 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Acta 2009 10.1016/j.bbagen.2009.06.014 7 0 0 9 "*Proteins|Amino Acid Sequence|Repetitive Sequences, Amino Acid|*Protein Domains|Arabidopsis|Multigene Family|Computational Biology|Leucine" 8 LRRC17 19336404 J. Biol. Chem. 2009 PMC2685711 10.1074/jbc.M807722200 16 4 4 9 "*Osteoclasts|*Receptor Activator of Nuclear Factor-kappa B|TNFSF11 protein, human|*RANK Ligand|TNFRSF11B protein, human|Osteoprotegerin|NFATC Transcription Factors|NF-kappa B|Cell Differentiation|Osteoblasts|Bone Resorption|Signal Transduction|Osteoclastogenesis|RELA protein, human|Transcription Factor RelA|Macrophages|Bone Marrow Cells|Proto-Oncogene Proteins c-fos" 8 SH3BGRL2 19941055 Biochem. Genet. 2009 10.1007/s10528-009-9310-y 1 0 0 11 "Transcription Factors|*Cell Differentiation|DNA-Binding Proteins|Erythroid Precursor Cells|Transcription, Genetic|EPO protein, human|Erythropoietin|Erythropoiesis|Cells, Erythroid|Globin|Cell Division" 8 SLC22A10 19679677 Drug Metab. Dispos. 2009 PMC2774986 10.1124/dmd.109.027177 0 0 0 14 "Male|Female|Pregnancy|Mice|Animals|*Tissue Distribution|ABCG2 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 2|Neoplasm Proteins|Membrane Transport Proteins|Organic Anion Transporters|bile acid binding proteins|Carrier Proteins|RNA, Messenger|Liver|Kidneys|Membrane Glycoproteins|*Biological Transport|Estrogens|Placenta|Gonadal Steroid Hormones|Androgens|Npt2b protein, mouse" 8 TMC5 20002769 Histopathology 2009 10.1111/j.1365-2559.2009.03449.x 12 0 1 25 "Humans|*Carcinoma, Renal Cell|Oncocytoma, renal|Kidney Neoplasms|Adenoma, Oxyphilic|Diagnosis, Differential|Biomarkers, Tumor|RNA, Messenger|Gene Expression|CD82 protein, human|Kangai-1 Protein" 8 ANKRD52 18186651 Biochemistry 2008 10.1021/bi7022877 37 8 1 174 "Humans|protein phosphatase 6|*Ankyrin Repeat|Phylogeny|SIT4 protein, S cerevisiae|Protein Phosphatase 2|Saccharomyces cerevisiae Proteins|NFKBIE protein, human|I-kappa B Proteins|PSMD10 protein, human|Proto-Oncogene Proteins|Saccharomyces cerevisiae|Amino Acid Sequence|Protein Binding|Sequence Homology, Amino Acid|Phosphorylation|HeLa Cells|Proteasome Endopeptidase Complex|ANKRD28 protein, human" 8 C3orf58 18621663 Science 2008 PMC2586171 10.1126/science.1157657 286 6 4 152 "Humans|*Autistic Disorder|Homozygote|Genes, Recessive|Chromosome Mapping|Pedigree|Mutations|Genetic Predisposition to Disease|Gene Expression|SLC9A9 protein, human|Sodium-Hydrogen Exchangers|Autism Spectrum Disorders|PCDH10 protein, human|Cadherins" 8 CAPSL 18927125 Hum. Mol. Genet. 2008 PMC2638779 10.1093/hmg/ddn342 54 0 2 1 "Humans|*Diabetes Mellitus, Type 1|*Interferon-Induced Helicase, IFIH1|*Leukocytes, Mononuclear|Genome-Wide Association Study|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genotype|Genetic Association Studies|*Gene Expression|DEAD-box RNA Helicases|Odds Ratio|European Continental Ancestry Group|Georgia|IFIH1 protein, human" 8 CAPSL 18563381 Diabetologia 2008 10.1007/s00125-008-1070-4 17 0 0 1 "Humans|*Diabetes Mellitus, Type 1|Genetic Susceptibility|Polymorphism, Single Nucleotide|Receptors, Interleukin-7|Genotype|Multiple Sclerosis|White" 8 DHDH 18836565 Mol. Vis. 2008 PMC2556974 1 0 0 8 "Humans|Cattle|Animals|*Chromosomes, Human, Pair 18|*Esotropia|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Chromosome Mapping|Haplotypes|Breeding|Chromosomes, Mammalian|Genetic Predisposition to Disease|Quantitative Trait Loci|*Exophthalmos|Telomeres" 8 KIAA0100 18549609 Zhongguo Shi Yan Xue Ye Xue Za Zhi 2008 2 0 0 65 "Humans|Male|Adult|Animals|Child|Rabbits|*Leukemia, Monocytic, Acute|*Computational Biology|Antigens, Neoplasm|Apoptosis Regulatory Proteins|Apoptosis|cDNA Library|Stomach Neoplasms|cDNA" 8 KPTN 19022414 Eur J Med Genet 2008 10.1016/j.ejmg.2008.09.007 4 0 1 45 "Female|Pregnancy|Humans|Adult|*Cleft Lip|*Intellectual Disability|Cleft Palate|Chromosome Deletion|Abnormalities, Multiple|*Heart Defects, Congenital|*Hearing Loss|Karyotyping|Translocation, Genetic|In Situ Hybridization, Fluorescence|*Musculoskeletal Abnormalities|*Chromosome Structures|*Palate|KPTN protein, human|Microfilament Proteins" 8 MAP10 18648382 J. Cereb. Blood Flow Metab. 2008 PMC3621146 10.1038/jcbfm.2008.79 53 1 3 10 "Animals|Rats|*Neuroprotection|*Ketoses|Middle Cerebral Artery Occlusion|Brain Ischemia|Neuroprotective Effect|Stroke|*Ketosis|Brain|*Ischemia|BCL2 protein, human|Proteins, BCL2|*Diet|Procollagen-Proline Dioxygenase|Disease Models, Animal|Upregulation" 8 SIDT1 18342537 Cytokine 2008 10.1016/j.cyto.2008.01.016 28 6 1 11 "*Interleukin-4|STAT6 protein, human|*STAT6 Transcription Factor|*Apoptosis|*Gene Expression|Signal Transduction|Cell Line, Tumor|Phenotype|Transcriptional Activation" 8 SLC38A10 18418736 J. Mol. Neurosci. 2008 10.1007/s12031-008-9046-x 33 1 1 23 "Mice|Animals|Rats|*Transporters, Amino Acid|Amino Acid Transport Systems, Neutral|Amino Acids|Amino Acid Sequence|Biological Transport|Amino Acids, Neutral|In Situ Hybridization|Phylogeny|Liver|Slc38a1 protein, mouse|Amino Acid Transport System A|Slc38a1 protein, rat" 8 WRAP73 18285824 Eur. J. Hum. 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Sci. Monit. 2020 PMC7111138 10.12659/MSM.921133 0 0 0 15 "Humans|Melanoma, Cutaneous Malignant|*Melanoma|Skin Neoplasms|*Alternative Splicing|*Prognosis|Network, Gene|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Bioinformatics|Gene Expression|Epistasis, Genetic|RNA" 7 RALGPS1 32156473 Gynecol. Oncol. 2020 10.1016/j.ygyno.2020.02.024 1 0 0 15 "Humans|Female|Endometrial Stromal Sarcoma|*Gene Fusion|*Sarcoma|*Soft Tissue Neoplasms|Endometrial Neoplasms|Proto-Oncogene Proteins|Repressor Proteins|*Genetic Profile|In Situ Hybridization, Fluorescence|Biomarkers, Tumor|*Pelvic Neoplasms|Genomics|BCOR protein, human|CDK4 protein, human|Cyclin-Dependent Kinase 4" 7 RBM33 32044717 Biomed. 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Genet. 2020 10.1007/s00439-020-02157-z 1 0 0 15 "Humans|*Genome-Wide Association Study|*Risk Factors|Trigonocephaly, Nonsyndromic|*Craniosynostoses|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|BMP7 protein, human|*Bone Morphogenetic Protein 7|Genotype|Case-Control Studies|White" 7 thap9 32190687 Biomed Res Int 2020 PMC7073484 10.1155/2020/8970340 0 0 0 6 "Humans|Female|*RNA, Long Noncoding|*Triple-Negative Breast Cancer|Network, Gene|mRNA|Prognosis|Gene Expression Regulation, Neoplastic|MicroRNAs|Gene Expression Profiling|Oncogenes|Carcinogenesis|Survival Analysis" 7 thap9 32021238 Onco Targets Ther 2020 PMC6707351 10.2147/OTT.S201832 1 0 0 6 "*RNA, Long Noncoding|Gastric Cancer|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Cell Movement|Up-Regulation|Signal Transduction" 7 TTC29 32655616 Front Genet 2020 PMC7325882 10.3389/fgene.2020.00569 0 0 0 22 "Sheep|Animals|*Quantitative Trait Loci|*DNA Copy Number Variations|Genome-Wide Association Study|*Phenotype|Chromosome Mapping|Quantitative Trait, Heritable|Genotype|Genetic Association Studies|Molecular Sequence Annotation|Polymorphism, Single Nucleotide" 7 TTC29 32034058 J. 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Dis. 2019 10.1093/infdis/jiz506 2 0 0 14 "Humans|Animals|*Influenza in Birds|*Influenza A virus|ANP32A protein, human|Intracellular Signaling Peptides and Proteins|RNA Replicase|Virus Replication|Influenzavirus B|Viral Proteins|Influenza, Human|Specificity, Host Species|RNA-Binding Proteins|Nuclear Proteins|Chickens" 7 B4GALNT4 31447885 Front Genet 2019 PMC6697060 10.3389/fgene.2019.00730 1 3 0 25 "Humans|Male|Middle Aged|Aged|*Prostate Cancer|*Prognosis|Transcriptional Regulator ERG|Gene Fusion|Oncogene Proteins, Fusion|Serine Endopeptidases|Cohort Studies|Bioinformatic|Biomarkers|Genetic Predisposition|Lymph Nodes|Russia" 7 B4GALNT4 30952207 BMC Genomics 2019 PMC6451222 10.1186/s12864-019-5621-5 0 1 0 25 "Animals|Humans|*Chickens|*High-Throughput Nucleotide Sequencing|Chromosome Mapping|Sequence Alignment|Sequence Analysis, DNA|leu-13 antigen|*Antigens, Differentiation|Amino Acid Sequence|IFITM3 protein, human|Membrane Proteins|RNA-Binding Proteins" 7 B4GALNT4 30898876 J. Biol. 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Chem. 2019 PMC6959985 10.1021/acs.analchem.9b02331 0 0 0 89 Humans|*Ubiquitin|Ubiquitin Ligase E3|Ubiquitination|Protein Binding|Protein Degradation|Amino Acid Sequence|Substrate Specificity|*Mass Spectrometry|HEK293 Cells 7 LHFPL4 31546163 Forensic Sci. Int. 2019 10.1016/j.forsciint.2019.109944 0 0 0 35 "Humans|Infant, Newborn|Infant|Child, Preschool|Child|Adolescent|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|*DNA Methylation|*B-DNA|CpG Islands|Forensic Genetics|Markers, DNA|Sequence Analysis, DNA|Aging|DNA Microarrays|Linear Models" 7 LHFPL4 30648560 Neuropharmacology 2019 10.1016/j.neuropharm.2019.01.008 5 0 0 35 "*Synapses|*Neurotransmitter Receptors|Carrier Proteins|Membrane Proteins|Receptors, Glycine|Protein Binding|Neurons|Receptors, GABA-A|Protein Transport|Postsynaptic Density|Binding Sites" 7 LHFPL4 31546163 Forensic Sci. 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Genet. 2019 PMC6699142 10.1016/j.ajhg.2019.06.014 3 0 0 57 Male|Female|Animals|Child|Humans|Cerebellar Hypoplasia|*Intellectual Disability|*Coloboma|*Nervous System Malformations|*Developmental Disabilities|*Cerebellum|Phenotype|*Epilepsy|Pedigree|Homozygote|Mutation|WD40 Repeats|Proteins 7 ZNF536 31649580 Front Psychol 2019 PMC6792478 10.3389/fpsyg.2019.02218 0 0 0 14 "Humans|*Creativity|*Schizophrenia|NRG1 protein, human|Neuregulin-1|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|*Healthy Subjects" 7 ZNF536 30929901 Cell 2019 PMC6494450 10.1016/j.cell.2019.01.048 15 0 0 14 "Humans|*Schizophrenia|*Phenotypes|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Brain|Gene Expression Regulation|Brain Mapping|Genome" 7 ACYP1 30103756 Mol. Cancer 2018 PMC6090611 10.1186/s12943-018-0865-2 6 0 0 12 "*Imatinib Mesylate|*Gastrointestinal Stromal Tumors|*CRISPR-Cas Systems|Gastrointestinal Neoplasms|Drug Resistance, Neoplasm|Proto-Oncogene Proteins c-kit|miRNAs|Antineoplastic Agents|Gene Expression Regulation, Neoplastic|Protein Kinase Inhibitors|Signal Transduction|Cell Line, Tumor|Cell Proliferation|*CRISPR" 7 C12orf4 30237576 Genet. Med. 2018 PMC6752307 10.1038/s41436-018-0138-x 13 0 0 31 "Exome|Genetic Testing|Sequence Analysis, DNA|High-Throughput Nucleotide Sequencing|Phenotypes|Genomics|Homozygote|Mutation|Genetic Variation" 7 C12orf57 29383837 Am. J. Med. Genet. 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Ther. 2018 10.1016/j.pharmthera.2018.01.008 6 3 0 214 "Humans|Female|Carcinoma, Hepatocellular|Liver Neoplasms|KEAP1 protein, human|Kelch-Like ECH-Associated Protein 1|Epigenesis, Genetic|Glycogen Synthase Kinase 3|NF-E2-Related Factor 2|*Signal Transduction|Cyclin-Dependent Kinases|protein-tyrosine kinase p55(blk)|*src-Family Kinases|Tumorigenesis|*Immunotherapy|Cell Cycle|CCND1 protein, human|Cyclin D1|Gene Expression Regulation, Neoplastic|CDK2 protein, human" 7 COX6B2 30054583 Neuropsychopharmacology 2018 PMC6135758 10.1038/s41386-018-0144-3 4 1 0 7 "Humans|Mice|Animals|*Alzheimer Disease|*Electron Transport Complex IV|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Genetic Association Studies|Polymorphism, Single Nucleotide|Case-Control Studies|Gene Expression|Hippocampus|LRPPRC protein, human|Neoplasm Proteins|Lrpprc protein, mouse|COX10 protein, mouse|Membrane Proteins|Alkyl and Aryl Transferases" 7 COX6B2 29416685 Oncotarget 2018 PMC5787428 10.18632/oncotarget.23453 1 27 0 7 "Humans|Female|Rats|Animals|estrogen receptor alpha, human|*Estrogen Receptor alpha|*Osteogenesis|Osteoblasts|Estrogen Receptor beta|*Cell Differentiation|*Signal Transduction|*Upregulation|Oestradiol|Estrogens|*Transcriptional Activation|Osteosarcoma|Promoter Regions, Genetic|Cell Line, Tumor|RNA, Messenger" 7 CPNE5 30272363 Oncol. Rep. 2018 10.3892/or.2018.6742 0 0 0 63 "Humans|*Esophageal Squamous Cell Carcinoma|*Esophageal Neoplasms|Neoplasm Recurrence, Local|*Prognosis|Carcinoma, Squamous Cell|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Esophagus|DNA Methylation|mRNA|Promoter Regions, Genetic|Down-Regulation|Cell Line, Tumor|CPNE5 protein, human|Carrier Proteins" 7 CPNE5 29627306 Toxicol. Lett. 2018 10.1016/j.toxlet.2018.04.002 3 3 0 63 "Mice|Animals|*Paraquat|NFE2L2 protein, human|*NF-E2-Related Factor 2|*RNA, Long Noncoding|*1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|*Substantia Nigra|MPTP Poisoning|Herbicides|Dopaminergic Neurons|Corpus Striatum|Dopamine|Parkinson Disease|Mice, Inbred C57BL|Oxidative Stress|Neurodegenerative Diseases" 7 DNAH3 30109710 Anim. Genet. 2018 PMC6175157 10.1111/age.12710 2 0 0 12 "Cattle|Male|Animals|Humans|Sperm Motility|*Fertility|Conception|Sperm|Genome-Wide Association Study|Single Nucleotide Polymorphism|Genomics|Genome|Spermatogenesis|Genotype|CNNM4 protein, human|Cation Transport Proteins|PKDREJ protein, human|Receptors, Cell Surface" 7 DNAH3 30084009 Mar. Biotechnol. 2018 10.1007/s10126-018-9845-1 0 2 0 12 "Male|Animals|*Triploidy|*RNA, Micro|*Testis|High-Throughput Nucleotide Sequencing|Gene Expression Profiling|Transcriptome|Diploids|Sex Differentiation|*Sterility|Cyprinidae|Real-Time Polymerase Chain Reaction" 7 DNAH3 29879995 J Transl Med 2018 PMC5992876 10.1186/s12967-018-1504-9 4 2 0 12 "Humans|*Exome|*Genetic Predisposition to Disease|Breast Cancer, Familial|*Breast Neoplasms|BRCA1 protein, human|BRCA1 Protein|Genes, BRCA2|BRCA2 Protein|*Base Sequence|Germ-Line Mutation|Pedigree|Mutation|Genotype|North Africa" 7 DNAJC17 29773831 Sci Rep 2018 PMC5958099 10.1038/s41598-018-26093-1 2 4 0 19 "Humans|Mice|Animals|Proteomics|*RNA Splicing|DNAJB1 protein, human|HSP40 Heat-Shock Proteins|Spliceosomes|RNA Precursors|Alternative Splicing|*Intranuclear Inclusion Bodies|Nuclear Proteins|Cell Nucleus|Heat Shock Protein|Congenital Hypothyroidism|HeLa Cells" 7 EMX2OS 30576338 PLoS ONE 2018 PMC6303026 10.1371/journal.pone.0209338 2 1 0 0 "*Thyroid Cancer, Papillary|*RNA, Long Noncoding|*Down-Regulation|Phosphatidylinositol 3-Kinases|Thyroid Cancer|Thyroid cancer, follicular|Adenocarcinoma, Follicular|Prognosis|Carcinoma, Papillary|Gene Expression Regulation, Neoplastic|empty spiracles homeobox proteins|Homeodomain Proteins|Transcription Factor|Biomarkers, Tumor|RNA, Messenger|Genes, Homeobox" 7 EMX2OS 30119681 J Transl Med 2018 PMC6098652 10.1186/s12967-018-1600-x 5 0 0 0 "*Fatigue Syndrome, Chronic|*RNA, Long Noncoding|*Fatigue|Killer Cells, Natural" 7 EMX2OS 29895819 Sci Rep 2018 PMC5997657 10.1038/s41598-018-27145-2 2 10 0 0 "Humans|Female|*Genome-Wide Association Study|Japan|Quantitative Trait Loci|*Phenotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Linkage Disequilibrium|MSI2 protein, human|RNA-Binding Proteins" 7 FBXO39 30008875 Oncol Lett 2018 PMC6036412 10.3892/ol.2018.8876 1 5 0 4 "Humans|*Osteosarcoma|*Apoptosis|bcl-2-Associated X Protein|Bone Neoplasms|Proto-Oncogene Proteins c-bcl-2|Cell Proliferation|Cell Line, Tumor|Caspase 3|Cell Cycle|FBXO39 protein, human|F-Box Proteins" 7 FBXO39 29802700 Asian Pac. J. Cancer Prev. 2018 PMC6031834 10.22034/APJCP.2018.19.5.1357 1 0 0 4 "Humans|*Prognosis|Iran|*Colorectal Cancer|Biomarkers, Tumor|Neoplasm Staging|*Oncogenes|Polycomb Repressive Complex 1|Real Time PCR|*Colonic Neoplasms|RNA, Messenger|FBXO39 protein, human|F-Box Proteins" 7 KLHDC2 30526872 Mol. Cell 2018 PMC6294321 10.1016/j.molcel.2018.10.021 6 0 0 89 "Humans|*Glycylglycine|Protein Conformation, beta-Strand|Protein Conformation, alpha-Helical|Ubiquitin|Cloning, Molecular|Protein Binding|Binding Sites|Protein Interaction Domains and Motifs|Substrate Specificity|Proteolysis|Crystallography, X-Ray|Proteasome|Gene Expression|HEK293 Cells|Genetic Vectors|Amino Acid Sequence|Models, Molecular|Sequence Alignment" 7 KLHDC2 29779948 Cell 2018 PMC6003881 10.1016/j.cell.2018.04.028 21 1 0 89 Humans|*Proteome|*Eukaryotes|Proteolysis|Ubiquitin|E3 Ligase|Proteasome Endopeptidase Complex|*Eukaryotic Cells|Protein Stability|Protein Binding|Amino Acid Sequence 7 KLHL31 30547757 BMC Genet. 2018 PMC6295101 10.1186/s12863-018-0703-y 2 0 0 23 "Humans|Male|Female|Child|*Sex Hormone-Binding Globulin|*Testosterone|*DNA Methylation|Cross-Sectional Studies|Longitudinal Studies|Polymorphism, Single Nucleotide|Genotype|*Testosterone Congeners" 7 LENEP 30304245 An. Acad. Bras. Cienc. 2018 10.1590/0001-3765201820170728 0 0 0 7 *Barium Sulfate|*DTPA|*Solubility|Barium|Oil Wells|Sulfates|Seawater|Minerals 7 LHFPL4 29742426 Cell Rep 2018 10.1016/j.celrep.2018.04.015 4 1 0 35 "Animals|Mice|neuroligin 2|*Cell Adhesion Molecules, Neuronal|*Nerve Tissue Proteins|Synapses|*Neurogenesis|Membrane Proteins|Synaptic Transmission|Neural Inhibition|Binding Proteins|Hippocampus" 7 LHFPL4 29742426 Cell Rep 2018 10.1016/j.celrep.2018.04.015 4 1 0 35 "Animals|Mice|neuroligin 2|*Cell Adhesion Molecules, Neuronal|*Nerve Tissue Proteins|Synapses|*Neurogenesis|Membrane Proteins|Synaptic Transmission|Neural Inhibition|Binding Proteins|Hippocampus" 7 LIMD2 30221696 Mol Med Rep 2018 10.3892/mmr.2018.9464 3 3 0 47 "Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|A549 Cells|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Down-Regulation|Upregulation|Cell Line, Tumor|*Neoplastic Processes|mRNA" 7 LIMD2 29560564 Endocr. Pathol. 2018 10.1007/s12022-018-9526-7 1 0 0 47 "Humans|*Thyroid Cancer, Papillary|*Proto-Oncogene Proteins B-raf|*Lymphatic Metastasis|Thyroid Neoplasms|Carcinoma, Papillary|Carcinoma|Mutations|Lymph Nodes|Follicular Thyroid Carcinoma|BRAF protein, human" 7 LIMD2 30221696 Mol Med Rep 2018 10.3892/mmr.2018.9464 3 3 0 47 "Humans|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|A549 Cells|Neoplasm Invasiveness|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Proliferation|Cell Movement|Down-Regulation|Upregulation|Cell Line, Tumor|*Neoplastic Processes|mRNA" 7 LIMD2 29560564 Endocr. Pathol. 2018 10.1007/s12022-018-9526-7 1 0 0 47 "Humans|*Thyroid Cancer, Papillary|*Proto-Oncogene Proteins B-raf|*Lymphatic Metastasis|Thyroid Neoplasms|Carcinoma, Papillary|Carcinoma|Mutations|Lymph Nodes|Follicular Thyroid Carcinoma|BRAF protein, human" 7 MDS2 30112902 Zhongguo Yi Liao Qi Xie Za Zhi 2018 10.3969/j.issn.1671-7104.2018.04.021 1 0 0 1 *Equipment Safety|Hospital Information Systems|Safety Management 7 MDS2 29444662 BMC Genomics 2018 PMC5813387 10.1186/s12864-018-4528-x 2 2 0 1 "*RNA Motif|Sequence Analysis, RNA|High-Throughput Nucleotide Sequencing|Exosomes|Binding Sites|MicroRNAs|Messenger RNA|Base Sequence" 7 MIR485 29916552 Mol Med Rep 2018 10.3892/mmr.2018.9186 3 5 0 0 "Humans|Female|*Uterine Cervical Neoplasms|*Cell Proliferation|MicroRNAs|Cell Movement|Neoplasm Invasiveness|Downregulation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Signal Transduction|Upregulation|Transcription Factors|Lymphatic Metastasis|Oncogenes|*Neoplastic Processes|*Colonic Neoplasms|Prognosis|MACC1 protein, human|MIRN485 microRNA, human" 7 MIR485 29860902 Cell Transplant 2018 PMC6050915 10.1177/0963689718761658 2 28 0 0 "Humans|*Endothelial Progenitor Cells|BDNF protein, human|*Brain-Derived Neurotrophic Factor|MicroRNAs|Cell Differentiation|Cells, Cultured|MIRN1183 microRNA, human|MIRN1294 microRNA, human|MIRN4717 microRNA, human|MIRN485 microRNA, human" 7 MOB3B 29802456 J. Cancer Res. Clin. Oncol. 2018 10.1007/s00432-018-2676-7 0 0 0 36 "Humans|*Protein Kinase Inhibitors|ErbB Receptors|Carcinoma, Non-Small-Cell Lung|Gefitinib|Erlotinib Hydrochloride|Quinazolines|Lung Neoplasms|Drug Resistance, Neoplasm|*Machine Learning|Gene Amplification|Mutation|Cell Line, Tumor|EGFR protein, human" 7 PCDHA6 30410030 Transl Psychiatry 2018 PMC6224395 10.1038/s41398-018-0281-9 4 1 0 81 "Humans|*Neurites|*Neurogenesis|Neurons|Neurite Outgrowth|Nerve Tissue Proteins|*Mutations|Cell Differentiation|Induced Pluripotent Stem Cells|Cells, Cultured|Pedigree|DISC1 protein, human|ZNF506 protein, human|Repressor Proteins|Kruppel-Like Transcription Factors" 7 RALGPS1 29523295 Med. Hypotheses 2018 10.1016/j.mehy.2018.02.009 2 4 0 15 "Humans|*Catatonia|Depressive Disorder, Major|Neuroleptic Malignant Syndrome|Schizophrenia|Antipsychotic Agents|Psychosis|Benzodiazepines|Parkinsonism|Periodicity|Anti-N-Methyl-D-Aspartate Receptor Encephalitis|Serotonin" 7 SPEF1 30535028 J Mol Cell Biol 2018 10.1093/jmcb/mjy014 8 1 0 26 "Animals|Mice|*Microtubules|calponin|*Microfilament Proteins|Axoneme|Cilia|Microtubule-Associated Proteins|Ependyma|TYRP1 protein, human|*Membrane Glycoproteins|Calcium-Binding Proteins|Cell Movement|Chromosome Segregation|Protein Binding|*Mammals|Amino Acid Sequence|Transductions, Signal|SPAG6 protein, mouse|Microtubule Proteins" 7 SPEF1 29514918 J. Cell Biol. 2018 PMC5940297 10.1083/jcb.201706058 9 6 0 26 "Animals|*Cell Polarity|*Microtubule|*Cell Signaling|Cilia|Xenopus Proteins|Xenopus laevis|Cytoskeleton|Cells, Epithelial|Protein Transport" 7 TBC1D22A 30064533 Twin Res Hum Genet 2018 10.1017/thg.2018.41 2 0 0 43 "Female|Humans|*Pedigree|DNA Copy Number Variations|*Monozygotic Twins|Twins, Dizygotic|Monozygotic Twinning|*Sequencing, Whole Genome|Phenotype|DNA, Mitochondrial|*Reproductive History" 7 TBC1D22A 29430824 Psychiatry Clin. Neurosci. 2018 10.1111/pcn.12645 2 0 0 43 "*Bipolar Disorder|Genome-Wide Association Study|*DNA Methylation|*Epigenome|*Schizophrenia|*Epigenetic|CpG Islands|Epigenesis, Genetic|Genetic Predisposition to Disease|Promoter Regions, Genetic" 7 TEKT2 29731491 J. Reprod. Dev. 2018 PMC6105735 10.1262/jrd.2018-024 0 4 0 24 "Male|Female|Mice|Animals|*Oocytes|Oogenesis|*Spermatogenesis|Ovaries|Germ Cells|Embryonic Development|Gene Expression Regulation, Developmental|Transcription Factors|Mice, Transgenic|mRNA|Cell Differentiation|Cell Nucleus|Tnp2 protein, mouse|Nuclear Proteins" 7 TEKT2 29642674 Asian-australas. J. Anim. Sci. 2018 PMC6212766 10.5713/ajas.18.0025 1 0 0 24 "Humans|Animals|Male|*Sperm Motility|*Buffaloes|prohibitin|*Actins|*Capping Protein, Actin|tektins|*Sperm|*Repressor Proteins|*Genes, Regulator|*Bison" 7 TGIF2LX 29960902 Arab J Gastroenterol 2018 10.1016/j.ajg.2018.05.001 0 0 0 15 "*DNA, Complementary|*Amplified Fragment Length Polymorphism Analysis|*Colorectal Neoplasms|Acid Anhydride Hydrolases|*Adenocarcinoma|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|Proteins, Homeo Domain" 7 WDR37 29929488 BMC Ophthalmol 2018 PMC6013877 10.1186/s12886-018-0820-4 2 1 0 57 7 ZNF536 30034349 Front Psychiatry 2018 PMC6043864 10.3389/fpsyt.2018.00290 18 3 0 14 "Humans|*Depressive Disorder, Major|Genome-Wide Association Study|*Deep Learning|*Antidepressive Agents|Selective Serotonin Reuptake Inhibitors|Psychiatric Status Rating Scales|Treatment Outcome|*Genetic Markers|Single Nucleotide Polymorphisms|Cohort Studies" 7 ZNF536 29731991 Oncotarget 2018 PMC5929434 10.18632/oncotarget.24924 2 0 0 14 "Humans|*Gene Amplification|*High-Throughput Nucleotide Sequencing|Neoplasm Recurrence, Local|*Liposarcoma, Well Differentiated|*Neoplasms, Adipose Tissue|*Mutations|Soft Tissue Neoplasms|Proto-Oncogene Proteins c-mdm2|Immunohistochemistry|Soft Tissue Sarcoma|In Situ Hybridization, Fluorescence|Cyclin-Dependent Kinase 4|Biomarkers, Tumor" 7 B4GALNT4 28853212 Mol Oncol 2017 PMC5663998 10.1002/1878-0261.12134 5 10 0 25 "Humans|Female|*Glycomics|Nitrogen-13|*Nitrogen Radioisotopes|Tandem Mass Spectrometry|*Cystadenocarcinoma, Serous|Carcinoma, Ovarian Epithelial|Chromatography, Liquid|Ovarian Neoplasms|Glycans|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Peritoneal Neoplasms|Cell Line, Tumor|Ovary" 7 B4GALNT4 28558694 BMC Genomics 2017 PMC5450142 10.1186/s12864-017-3801-8 5 0 0 25 "Animals|*Galliformes|Genome|Phylogeny|Gallus gallus|Genetic Loci|Genetic Variation|Sequence Analysis, DNA|*DNA Mutational Analysis" 7 C21orf91 28693416 BMC Genomics 2017 PMC5502484 10.1186/s12864-017-3878-0 9 1 0 51 Humans|Pregnancy|Female|*Gene Regulatory Networks|*Fetal Growth|*Transcriptome Analysis|Placenta|Birth Weight|Transcriptome 7 C6orf89 28476309 Exp. Cell Res. 2017 10.1016/j.yexcr.2017.05.002 1 10 0 113 "Humans|*Mucin 5AC|ELANE protein, human|*Leukocyte Elastase|*Receptors, Bombesin|*Cells, Epithelial|*Signal Transduction|Nuclear Factor-Kappab|Extracellular Signal Regulated Kinases|Bronchi|EGFR protein, human|Epidermal Growth Factor Receptor|TYRP1 protein, human|*Membrane Glycoproteins|Phosphorylation|Cell Line|Mucus|Interleukin 1|BRAP protein, human" 7 CCDC25 28789463 Oncol Lett 2017 PMC5529998 10.3892/ol.2017.6446 1 0 0 32 "Proteomics|*Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|EGFR protein, human|Epidermal Growth Factor Receptor|Cell Line, Tumor|Cell Migration|Bile Acids|Cyclooxygenase 2" 7 CDH26 28051089 Mucosal Immunol 2017 PMC5496811 10.1038/mi.2016.120 0 37 0 16 "Humans|Integrins|Cell Adhesion|Cadherins|*Protein Binding|Lymphocyte Activation|Cells, Epithelial|Cell Line|Cell Differentiation|Integrin alpha Chains|*Inflammation" 7 CDK20 28939663 Gut 2017 PMC5961939 10.1136/gutjnl-2017-314032 20 27 0 214 "*Carcinoma, Hepatocellular|*Liver Neoplasms|*Myeloid-Derived Suppressor Cells|*Immunosuppression|*Immune Tolerance|protein-tyrosine kinase p55(blk)|*src-Family Kinases|Tumor Microenvironment|Cyclin-Dependent Kinases|Gene Expression Regulation, Neoplastic|Signal Transduction|Cell Proliferation|Tumor Cells, Cultured|Interleukin-6|*Immunologic Deficiency Syndromes" 7 CDK20 28534518 Oncogene 2017 10.1038/onc.2017.161 15 3 0 214 "Humans|KEAP1 protein, human|*Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|Apoptosis|Cell Line, Tumor|G2 Phase Cell Cycle Checkpoints|Neoplasm Recurrence, Local|*Lung Cancer|*Lung|Drug Resistance, Neoplasm|Cell Proliferation|Reactive Oxygen Species|Signal Transduction|Mutation" 7 CPNE5 28965411 J. Proteome Res. 2017 10.1021/acs.jproteome.7b00223 1 0 0 63 "Humans|Male|*Proteomics|Proteome|Databases, Protein|Tandem Mass Spectrometry|Amino Acid Sequence|Post-Translational Modifications|Alternative Splicing|Peptides|Hippocampus|Open Reading Frames|*Chromosome|ACTN4 protein, human|Actinin|CPNE5 protein, human|Carrier Proteins" 7 CPNE5 28340271 Genet. Mol. Res. 2017 10.4238/gmr16019522 5 0 0 63 "Pregnancy|Cattle|Animals|Female|*Polymorphism, Single Nucleotide|Sexual Maturation|*RNA Sequence|Breeding|Fertility|Quantitative Trait Loci|Genotype|Sequencing, RNA|Transcriptome|Genetic Selection|RNA" 7 DDX50 28676847 Front Cell Infect Microbiol 2017 PMC5476785 10.3389/fcimb.2017.00269 3 19 0 58 "Humans|Chlorocebus aethiops|Animals|*Hantaan virus|*Neutralizing Antibody|Hemorrhagic Fever with Renal Syndrome|*Antiviral Agents|Hantavirus|Hantavirus Infections|Antibodies, Viral|Vero Cells|*B-Lymphocytes|Viral Vaccines|Humoral Immunity|Viral Proteins|Virus Titer|Virus Replication|DDX21 protein, human|DEAD-box RNA Helicases" 7 DDX50 28181036 Arch. Virol. 2017 10.1007/s00705-017-3250-3 0 2 0 58 "*Dengue Virus|DDX58 protein, human|DEAD Box Protein 58|Dengue|*Transcriptional Activation|*Upregulation|Interferon-Induced Helicase, IFIH1|Virus Replication|DEAD-box RNA Helicases|Interferon-beta|Immunity, Innate|Cell Line|Antiviral Agents" 7 DMRTC2 29019938 Genes (Basel) 2017 PMC5664117 10.3390/genes8100267 9 13 0 7 "Humans|Male|*Cryptorchidism|Brachyury protein|Sexual Maturation|*Fetal Proteins|*T-Box Domain Proteins|Spermatogonia|Testes|Infertility, Male|Buserelin|*Reproduction|*Cell Differentiation|TERT protein, human|Telomerase|PAX7 protein, human|PAX7 Transcription Factor" 7 DNAH3 29110840 Lung Cancer 2017 10.1016/j.lungcan.2017.10.001 1 0 0 12 "*Lung Cancer|Lung Adenocarcinoma|Adenocarcinoma|*Pneumonia|Lymphatic Metastasis|Biomarkers, Tumor|Tumor Microenvironment|Cytoskeletal Proteins" 7 DNAJC17 29159607 J. Endocrinol. Invest. 2017 10.1007/s40618-017-0795-7 0 3 0 19 "Humans|Infant, Newborn|Mice|Animals|*Thyroid Dysgenesis|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Congenital Hypothyroidism|PAX8 Transcription Factor|*Mutations|Paired Box Transcription Factors|Homeodomain Proteins|Homeobox Protein Nkx-2.5|Receptors, Thyrotropin|Thyroid Gland|Phenotype|Pedigree|Forkhead Transcription Factors" 7 HN1L 29249663 Stem Cell Reports 2017 PMC5768915 10.1016/j.stemcr.2017.11.010 8 13 0 124 "Humans|*Triple-Negative Breast Cancer|leptin receptor, human|*Receptors, Leptin|Neoplasm Recurrence, Local|STAT3 protein, human|*STAT3 Transcription Factor|Cancer Stem Cell|Signal Transduction|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Proliferation|Docetaxel|Prognosis" 7 HN1L 29053395 Cancer Biol. Ther. 2017 PMC5710669 10.1080/15384047.2017.1385678 1 2 0 124 "Humans|Mice|Animals|*Carcinoma, Non-Small-Cell Lung|*Lung Neoplasms|Mice, Nude|*Cell Proliferation|Cell Cycle|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Upregulation|shRNA|Signal Transduction|Heterografts|Kaplan-Meier Analysis" 7 KLHL31 28872460 J. Clin. Invest. 2017 PMC5617662 10.1172/JCI93445 10 2 0 23 "Mice|Animals|*Myopathy, Congenital|Sarcomeres|Muscle, Skeletal|Muscle Contraction|Centronuclear Myopathy|FLNC protein, human|Filamin C|Transcription Factor|Mice, Knockout|Transcriptional Activation|Gene Expression Regulation|Ubiquitination" 7 LHFPL4 28978485 Cell Rep 2017 PMC5640807 10.1016/j.celrep.2017.09.025 21 9 0 35 "Synapses|Receptors, GABA-A|Inhibitory Postsynaptic Potentials|Synaptic Transmission|Pyramidal Cells|TSPAN32 protein, human|*Tetraspanins|CA1 Region, Hippocampal|Neural Inhibition|Patch-Clamp Techniques|Neurons|Carrier Proteins|Membrane Proteins|Hippocampus|gamma-Aminobutyric Acid|*Clustering" 7 LHFPL4 28978485 Cell Rep 2017 PMC5640807 10.1016/j.celrep.2017.09.025 21 9 0 35 "Synapses|Receptors, GABA-A|Inhibitory Postsynaptic Potentials|Synaptic Transmission|Pyramidal Cells|TSPAN32 protein, human|*Tetraspanins|CA1 Region, Hippocampal|Neural Inhibition|Patch-Clamp Techniques|Neurons|Carrier Proteins|Membrane Proteins|Hippocampus|gamma-Aminobutyric Acid|*Clustering" 7 MAGEB16 29079788 Sci Rep 2017 PMC5660239 10.1038/s41598-017-14561-z 4 5 0 2 "Male|Mice|Animals|*Pluripotent Stem Cells|*Cell Differentiation|Embryonic Stem Cells|*Mesoderm|Transcriptome|Cells, Cultured|shRNA" 7 MAGEB16 28555782 Transfusion 2017 10.1111/trf.14172 0 0 0 2 "Neuroacanthocytosis, Mcleod Type|*Neuroacanthocytosis|Kell Blood-Group System|Amino Acid Transport Systems, Neutral|Phenotype|Point Mutations|Syndrome" 7 MIR485 29048626 Int. 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Oncol. 2017 10.3892/ijo.2017.4122 8 3 0 0 "Humans|Adult|*Glioblastoma|miRNA|Cell Proliferation|Gene Expression Regulation, Neoplastic|Glioma|Brain Neoplasms|Cell Movement|Downregulation|Cell Line, Tumor|Signal Transduction|Apoptosis|Upregulation|Disease Progression|Prognosis|Pathways, ERK|PAK4 protein, human|p21-Activated Kinases|MIRN485 microRNA, human" 7 MOB3B 28792927 Nature 2017 PMC5706657 10.1038/nature23451 0 5 0 36 "Humans|Animals|*RNA, Long Noncoding|Vemurafenib|Melanoma|Proto-Oncogene Proteins B-raf|Protein Kinase Inhibitors|Indoles|Sulfonamides|Drug Resistance, Neoplasm|Cell Line, Tumor|CRISPR|Gene Expression Regulation, Neoplastic|MAP Kinase Signaling System|Activation, Transcriptional" 7 MOB3B 28084441 Sci Rep 2017 PMC5233981 10.1038/srep40636 0 10 0 36 "Humans|Male|*Prostate|*DNA Methylation|Prostate Cancer|Prostatectomy|Epigenetic|Biopsy, Needle|Glutathione S-Transferase pi|Epigenesis, Genetic|Promoter Regions, Genetic|Biomarkers, Tumor|Biopsy|Gene Expression Regulation, Neoplastic|KLF8 protein, human|Repressor Proteins" 7 PRPSAP1 28732507 World J Surg Oncol 2017 PMC5521104 10.1186/s12957-017-1194-4 2 1 0 54 "*Carcinoma, Hepatocellular|*Liver Neoplasms|*RNA, Long Noncoding|*Hot Temperature|Neoplasm Recurrence, Local|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Expression Profiling|Gene Regulatory Networks|Transcriptome|RNA, Messenger" 7 RBM33 28942176 Microb. Pathog. 2017 10.1016/j.micpath.2017.09.015 0 2 0 77 "Humans|Animals|*Brugia malayi|pepsin B|*Pepsin A|Leukocytes, Mononuclear|*Lymphatic Filariasis|Antigens, Helminth|Antibodies, Helminth|Helminth Proteins|Cytokines|Recombinant Proteins|Nitric Oxide|Immunologic Factors|*Signal Transduction|Immunoglobulin G" 7 RBM33 28207535 Medicine (Baltimore) 2017 PMC5319524 10.1097/MD.0000000000006117 6 0 0 77 Humans|Case-Control Studies|*Asians|*Obesity|Body Mass Index|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Genome-Wide Association Study|Genetic Predisposition to Disease|Genotype|Genetic Linkage 7 SAMD7 28900001 Proc. Natl. Acad. Sci. 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Genet. 2017 PMC5458336 10.1093/hmg/ddx113 4 5 0 26 "Humans|*Exome|Genome-Wide Association Study|*Heart Rate|*Oligonucleotide Array Sequence Analysis|Genetic Loci|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Gene Frequency|Alleles|European Continental Ancestry Group" 7 SPEF1 28967676 Vox Sang. 2017 10.1111/vox.12566 1 0 0 26 *White Blood Cells|*Red Blood Cell|Leukocyte Count|Plateletpheresis|Flow Cytometry|Blood Component Transfusion|Quality Control|*Polymerase Chain Reaction|Reproducibility of Results 7 TGIF2LX 28843229 Asian Pac. J. Cancer Prev. 2017 PMC5697467 10.22034/APJCP.2017.18.8.2101 1 12 0 15 "Humans|Mice|Animals|Mice, Nude|*Adenocarcinoma|*Colon Cancer|TYRP1 protein, human|*Membrane Glycoproteins|Signal Transduction|Neovascularization, Pathologic|Cell Proliferation|Transforming Growth Factor beta|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Homeodomain Proteins|Transcription Factor|Transfections|Vascular Endothelial Growth Factor A|Colon" 7 tmem138 29025994 Science 2017 PMC5759959 10.1126/science.aan8433 48 8 0 70 "Humans|*Skin Pigmentation|Gene Frequency|Haplotypes|European Continental Ancestry Group|Asian Continental Ancestry Group|Genetics, Population|Alleles|Selection, Genetic|African Continental Ancestry Group|Ethnic Groups|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Genotype|Biological Evolution|Antiporters" 7 tmem138 28289185 J. Med. Genet. 2017 PMC5557276 10.1136/jmedgenet-2016-104436 0 15 0 70 "*Oral-Facial-Digital Syndrome|Disease, Polycystic Kidney|Ciliary Motility Disorders|Abnormalities, Multiple|Encephalocele|Retinitis Pigmentosa|Heterozygote|Membrane Proteins|Mutation|Face" 7 WDR37 28758108 Int J Genomics 2017 PMC5512050 10.1155/2017/1746426 2 2 0 57 7 Zswim6 29198722 Am. J. Hum. Genet. 2017 PMC5812890 10.1016/j.ajhg.2017.10.009 5 0 0 42 "Humans|*Intellectual Disability|*Limb Deformities, Congenital|*Codon, Nonsense|Acromelic Frontonasal Dysostosis|Mandibulofacial Dysostosis|Exome|Abnormalities, Multiple|Frameshift Mutation|Exon|Phenotypes|Mutation|Nonsense Mediated mRNA Decay|ZSWIM6 protein, human|DNA-Binding Proteins" 7 Zswim6 28433741 Neurobiol. Dis. 2017 PMC5703052 10.1016/j.nbd.2017.04.013 3 3 0 42 "Mice|Animals|Genome-Wide Association Study|*Corpus Striatum|Acromelic Frontonasal Dysostosis|Mandibulofacial Dysostosis|Mice, Knockout|Dopamine|Hyperkinesis|DNA-Binding Proteins|Amfetamine|Intellectual Disability|Phenotype" 7 ACTL7B 27878761 Mol. Neurobiol. 2016 PMC5441979 10.1007/s12035-016-0282-8 2 3 0 2 "Humans|United States|Aged|*Genome-Wide Association Study|*African Americans|*Smell|*European Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Genotype|NR5A2 protein, human|Receptors, Cytoplasmic and Nuclear|PCDH10 protein, human|Cadherins|FSTL5 protein, human|Follistatin-Related Proteins" 7 C12orf4 27311568 Clin. Genet. 2016 10.1111/cge.12821 4 0 1 31 "Humans|*Intellectual Disability|Genes, Recessive|Pedigree|Sequencing, Whole Exome|Homozygote|Phenotype|Exome|Mutations|Genotype|Mutation, Missense|Founder Effect|Frameshift Mutation|Amino Acid Sequence|Family|Finland|C12orf4 protein, human|Intracellular Signaling Peptides and Proteins" 7 C1QTNF8 27443788 Br. J. Pharmacol. 2016 PMC5406291 10.1111/bph.13559 6 11 0 19 "Humans|*Relaxin|*Complement C1q|*Signal Transduction|Receptors, Peptide|Glioblastoma|Receptors, G-Protein-Coupled|Brain Neoplasms|TNF protein, human|*Tumor Necrosis Factor-alpha|Isoforms|Cell Movement|Cathepsin B|Insulins" 7 C21orf91 27404227 Sci Rep 2016 PMC4941730 10.1038/srep29514 6 15 1 51 "Humans|Mice|Animals|Down Syndrome Critical Region|*Down Syndrome|DNA Copy Number Variations|*Neurogenesis|*Cerebral Cortex|Nerve Tissue Proteins|Interneurons|Disease Models, Animal|CCDC85B protein, human|Repressor Proteins|Adaptor Proteins, Signal Transducing" 7 CCDC25 26851141 Schizophr. Res. 2016 10.1016/j.schres.2016.01.043 4 1 0 32 "Humans|*Schizophrenia|SNPs|Case-Control Studies|Genetic Predisposition to Disease|Carrier Proteins|Nerve Tissue Proteins|Genotype|*Plasma|NDEL1 protein, human|MAD1L1 protein, human|Nuclear Proteins|Cell Cycle Proteins" 7 CDH26 27905513 Sci Rep 2016 PMC5131482 10.1038/srep38096 17 1 0 16 "Pregnancy|Female|Animals|*Litter Size|*Polymorphism, Single Nucleotide|*Genome|*Goats|*Phenotype|Genotype|Fecundity|Selection, Genetic|Genes, cdc|China" 7 CDH26 26970242 Allergy 2016 10.1111/all.12879 8 0 1 16 Humans|*Eosinophilic Esophagitis|*Eosinophils|Esophagus|Gastroesophageal Reflux|Mast Cells 7 CHRAC1 27128794 Mol. Carcinog. 2016 10.1002/mc.22493 6 0 0 43 "Humans|Female|Genome-Wide Association Study|*Allelic Imbalance|Genetic Predisposition to Disease|Genotypes|Polymorphism, Single Nucleotide|Allele|Prognosis|Case-Control Studies|Transcription Factors|Risk Factors|Chromosomes|China" 7 CWF19L1 27016154 Am. J. Med. Genet. A 2016 10.1002/ajmg.a.37632 3 0 0 41 Child|Humans|Male|Female|*Intellectual Disability|*Whole Exome Sequencing|*Exome|Cerebellar Hypoplasia|Nervous System Malformations|Cerebellar Ataxia|Homozygote|Developmental Disabilities|Cerebellum|Pedigree|Mutations|*Cerebellar Diseases|Phenotype|Magnetic Resonance Imaging|Genetic Linkage|Atrophy|Turkey 7 DMRTC2 27828963 PLoS Genet. 2016 PMC5102403 10.1371/journal.pgen.1006429 9 73 1 7 "Humans|Male|Mice|Animals|CCNE1 protein, human|*Cyclin E|*Proteomics|*Oncogene Proteins|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin|Transcription Factors|Cell Cycle|Cell Proliferation|Spermatogenesis" 7 DMRTC2 27150017 Sci Rep 2016 PMC4858678 10.1038/srep25667 7 34 1 7 "Female|Mice|Animals|*Mouse Embryonic Stem Cells|*Transcription Factor|*Gene Expression Profiling|*Microarray Analysis|Cell Differentiation|Embryonic Stem Cells|Transcriptome|Gene Expression Regulation, Developmental|Cell Line|Mesoderm" 7 DNAH3 27581094 J. Proteome Res. 2016 PMC5099979 10.1021/acs.jproteome.6b00437 6 0 1 12 "Male|Humans|Tandem Mass Spectrometry|HEK293 Cells|Proteome|Databases, Protein|Proteomics|Bioinformatic|Peptides|Spermatozoa|*Data Management" 7 FBXO39 27635108 Dis. Markers 2016 PMC5007337 10.1155/2016/1987505 4 3 1 4 "Humans|Male|*Prognosis|*Testis|*Colorectal Cancer|MAGEA3 protein, human|Neoplasm Proteins|Antigens, Neoplasm|KDM5B protein, human|Jumonji Domain-Containing Histone Demethylases|Gene Expression Regulation, Neoplastic|Repressor Proteins|Biomarkers, Tumor|Nuclear Proteins|Membrane Proteins|DNA Methylation|mRNA|Cell Line, Tumor|*Colon Cancer|Gene Expression Profiling" 7 GPR149 27434957 Klin Khir 2016 2 0 0 1 "Humans|Male|Adenocarcinoma|Pancreatic Carcinoma|Pancreatic Neoplasms|*Prostatic Cancer|kallikrein-related peptidase 3, human|Prostate Specific Antigen|Benign Prostatic Hyperplasia|Prostate|Biomarkers, Tumor|Epigenesis, Genetic|DNA Methylation|Neoplasm Proteins|*Microarray Analysis|LRRC3B protein, human" 7 GPR149 26888156 Brain Struct Funct 2016 10.1007/s00429-016-1195-z 15 0 0 1 Rats|Animals|*Habenula|Neurons|Glutamate|Thalamus|Acetylcholine|*Microarray Analysis|*Energy Expenditure 7 IGSF5 29283236 Usp Fiziol Nauk 2016 0 2 0 16 "Humans|HIV Infections|F11R protein, human|Cell Adhesion Molecules|Receptors, Cell Surface|Platelet Adhesiveness|Atherosclerosis|Junctional Adhesion Molecules|Cell Adhesion|Apolipoproteins E|Blood Platelets|Endothelial Cells|Leukocytes|Thrombosis|Inflammation|Cell Differentiation|Cells, Cultured" 7 KCNQ1DN 27108355 Forensic Sci. Int. 2016 10.1016/j.forsciint.2016.03.047 4 0 0 8 "Humans|Female|Adolescent|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|CpG Islands|DNA Methylation|Epigenesis, Genetic|*Real-Time Polymerase Chain Reaction|Aging|DNA" 7 LIMD2 27564309 Epigenetics 2016 PMC5048720 10.1080/15592294.2016.1216284 18 6 1 47 "Humans|*Metabolic Syndrome|*Epigenome|Leukocytes, Mononuclear|*Obesity|DNA Methylation|Epigenesis, Genetic|CpG Islands|Body Mass Index|Genome-Wide Association Study|*Suppressor of Cytokine Signaling Proteins|SOCS3 protein, human|Suppressor of Cytokine Signaling 3 Protein|European Continental Ancestry Group|Cohort Studies" 7 LIMD2 27564309 Epigenetics 2016 PMC5048720 10.1080/15592294.2016.1216284 18 6 1 47 "Humans|*Metabolic Syndrome|*Epigenome|Leukocytes, Mononuclear|*Obesity|DNA Methylation|Epigenesis, Genetic|CpG Islands|Body Mass Index|Genome-Wide Association Study|*Suppressor of Cytokine Signaling Proteins|SOCS3 protein, human|Suppressor of Cytokine Signaling 3 Protein|European Continental Ancestry Group|Cohort Studies" 7 MAGEB16 26879937 J Transl Med 2016 PMC4755000 10.1186/s12967-016-0809-9 5 12 1 2 "Rats|Animals|*Urinary Bladder|*Urinary Bladder Diseases|Urothelium|Rats, Sprague-Dawley|*Diet, High-Protein|Apoptosis|urea transporter|Membrane Transport Proteins|Urea|*Blood Urea Nitrogen|DNA Damage" 7 RALGPS1 27149377 PLoS ONE 2016 PMC4858283 10.1371/journal.pone.0154840 5 20 1 15 "Humans|*GTPases|*Lung Cancer|Lung Carcinoma, Non-Small-Cell|ral Protein|ral Guanine Nucleotide Exchange Factor|CCND1 protein, human|Cyclin D1|Cell Cycle|Cell Proliferation|Signal Transduction|Cell Line, Tumor|ras Oncogenes|Cell Survival|p21 Cell Cycle Regulator|*Cell Division|Cell Cycle Arrest|Downregulation|RalGps2 protein, human" 7 SAMD7 26887858 Sci Rep 2016 PMC4758057 10.1038/srep21307 5 1 1 26 "Mice|Animals|*Rhodopsin|*Retinitis Pigmentosa|*Homozygote|*Mutation|Homeodomain Proteins|Retinal Rod Photoreceptor Cells|Eye Proteins|Trans-Activators|Retina|Promoter Regions, Genetic|Transcription Factor|Pedigree|Gene Expression Regulation|Phenotype" 7 SLC25A39 26865615 J. Neurosci. 2016 PMC6602013 10.1523/JNEUROSCI.3432-15.2016 5 0 1 16 "Animals|*Drosophila|Drosophila Proteins|*Mitochondria|Neuromuscular Junction|Synaptic Transmission|Drosophila melanogaster|Synaptic Vesicles|Synapses|Neurons|Mitochondrial Proteins|Animals, Genetically Modified|Mutations" 7 SLF2 27565207 Plant Cell Physiol. 2016 10.1093/pcp/pcw152 0 1 0 26 "*Petunia|CACUL1 protein, human|Self-Incompatibility in Flowering Plants|Pollen|F-Box Proteins|Ribonucleases|Gene Expression Regulation, Plant|Plant Proteins|ATP dependent 26S protease|Proteasome Endopeptidase Complex|Flowers|Plants, Genetically Modified" 7 TEKT2 27883267 Mol. Reprod. Dev. 2016 10.1002/mrd.22763 0 0 0 24 "Cattle|Male|Animals|tektins|calyculin A|Acrosome Reaction|*Spermatozoa|Acrosome|Microtubule Proteins|*Oxazoles|Sperm Head|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Flagella|*Translocation, Genetic|Plasma Membrane" 7 TGIF2LX 27699219 JCI Insight 2016 PMC5033889 10.1172/jci.insight.86837 16 0 0 15 "Humans|Male|*Carcinoma, Non-Small-Cell Lung|*Lung Cancer|*Testis|Antigens, Neoplasm|Prognosis|Immunotherapy|Gene Expression Regulation, Neoplastic|Membrane Proteins|*Cancer of Testis|Cohort Studies|TKTL1 protein, human|Transketolase" 7 TGIF2LX 27309477 Acta Med Iran 2016 5 0 0 15 "Male|Humans|Amplified Fragment Length Polymorphism Analysis|Downregulation|Transfections|Colorectal Cancer|Gene Expression Regulation, Neoplastic|Homeodomain Proteins|Cell Line, Tumor|Genetic Vectors|cDNA|Cell Proliferation|*Genes, X-Linked|Transforming Growth Factor beta|Morphogenesis" 7 tmem138 27434533 Clin. Genet. 2016 10.1111/cge.12836 0 0 0 70 "Humans|Agenesis of Cerebellar Vermis|*Kidney Diseases, Cystic|*Eye Abnormalities|*Abnormalities, Multiple|*Cerebellum|*Retina|Mutations|Pedigree|Membrane Proteins|Sequencing, Whole Exome|Magnetic Resonance Imaging" 7 tmem138 26982032 PLoS Biol. 2016 PMC4794247 10.1371/journal.pbio.1002416 31 19 1 70 "Animals|Humans|*Cilia|Proteomics|Meckel syndrome type 1|Ciliary Motility Disorders|Meckel Syndrome, Type 4|Polycystic Kidney Diseases|Caenorhabditis elegans|Encephalocele|Caenorhabditis elegans Proteins|Retinitis Pigmentosa|Orofaciodigital syndrome 6|Orofaciodigital Syndromes|Proteins, Membrane-Associated|Protein Transport|Liver|Polydactyly|Cep290 protein, human|Antigens, Neoplasm" 7 ZFAND2B 27090962 Exp. 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Genet. 2015 PMC4470468 10.1038/ng.3270 0 0 5 19 "Humans|PCSK9 protein, human|Proprotein Convertase 9|*Risk Factors|*Phenotypes|Exome|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Heterozygote|*Chronic Disease" 7 C21orf91 26221053 Sci Signal 2015 10.1126/scisignal.aaa8441 17 4 1 51 "Humans|Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Factor B|*Signal Transduction|MicroRNAs|Gene Expression Regulation, Neoplastic|NF-kappa B|transcription factor nuclear factor 1|*NFI Transcription Factors|Cell Proliferation|Hep G2 Cells|Cell Line, Tumor|*Hepatocyte|NOS2 protein, human|Tumor Necrosis Factor-alpha|TRIM23 protein, human|GTP-Binding Proteins|MIRN194 microRNA, human" 7 C6orf89 26460487 J. Cell. 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Dyn. 2015 PMC4449281 10.1002/dvdy.24279 0 7 0 5 "Animals|*Drosophila|*Genes, Homeobox|Drosophila Proteins|Drosophila melanogaster|Transcription Factors|Enhancer Elements, Genetic|Homeodomain Proteins|Gene Expression Regulation, Developmental|Animals, Genetically Modified|DNA Transposable Elements|Saccharomyces cerevisiae Proteins|Promoter Regions, Genetic|Genes, Reporter" 7 FBXO39 26537429 Sci Rep 2015 PMC4633681 10.1038/srep16264 5 2 1 4 "Animals|*Quantitative Trait Loci|*Genome-Wide Association Study|*Circadian Rhythm|Period Circadian Proteins|SNPs|*Hypothalamus|*Genes, Regulator|Phenotype|*Adaptation, Psychological" 7 HN1L 26220383 Epilepsy Res. 2015 10.1016/j.eplepsyres.2015.05.014 1 1 0 124 Humans|*Lamotrigine|*Genome-Wide Association Study|*Anticonvulsants|*Epilepsy|*Skin Rash|Triazines|Drug Eruptions|Gene Frequency|Genotype|Asian Continental Ancestry Group 7 KCNQ1DN 26679211 Epigenomics 2015 10.2217/epi.15.91 4 0 0 8 "Humans|Female|Pregnancy|*DNA Methylation|*Prenatal Exposure Delayed Effects|CpG Islands|Maternal Exposure|Epigenesis, Genetic|Placenta|Birth Weight|*DNA|Genome-Wide Association Study" 7 KLHL31 25796573 Dev. 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Med. 2015 10.1038/nm.4013 9 3 0 62 "Humans|Mice|Animals|IGF1 protein, human|*Insulin-Like Growth Factor I|*Proteostasis|Proteomics|*Signal Transduction|Receptor, IGF Type 1|insulin-related factor|Insulin|Carrier Proteins|Caenorhabditis elegans|Myeloproliferative Disorders|Proteasome Endopeptidase Complex|Longevity|Mutation|JAK2 protein, human|Janus Kinase 2" 7 ZFAND2B 26337389 Mol. Biol. Cell 2015 PMC4626058 10.1091/mbc.E15-02-0085 11 35 1 62 Ubiquitin|Proteasome|Endoplasmic Reticulum|Ubiquitination|Molecular Chaperones|Cell Cycle Proteins|Valosin Containing Protein|Protein Folding|Adenosine Triphosphatases|Posttranslational Modifications|Nuclear Proteins|Signal Sequence|Cytosol|*Quality Control 7 Zswim6 26706854 Clin. Genet. 2015 PMC5025718 10.1111/cge.12721 6 0 1 42 "Humans|Female|Acromelic Frontonasal Dysostosis|*Mosaicism|*Mandibulofacial Dysostosis|Limb Deformities, Congenital|*Mutation|Frontonasal dysplasia|Craniofacial Abnormalities|Abnormalities, Multiple|Heterozygote|Face|ZSWIM6 protein, human|DNA-Binding Proteins" 7 Zswim6 25742292 PLoS ONE 2015 PMC4350917 10.1371/journal.pone.0118488 5 1 1 42 "Humans|Female|Child|Pregnancy|*Genome-Wide Association Study|*Parity|Prospective Studies|SNPs|Genotype|Phenotype|Quantitative Trait Loci|Genetic Predisposition to Disease|Interactions, Gene-Environment|Fertility|*Ethnic Groups|Bangladesh|ZSWIM6 protein, human|DNA-Binding Proteins" 7 ACYP1 26290712 J Anim Sci Technol 2014 PMC4540274 10.1186/2055-0391-56-23 2 1 0 12 "Swine|Animals|Republic of Korea|Breeding|Genome|Selection, Genetic|Genomics|Genotype|Single Nucleotide Polymorphisms|Phenotype|High-Throughput Nucleotide Sequencing|Oligonucleotide Array Sequence Analysis" 7 ANP32C 25156960 Bioessays 2014 PMC4270211 10.1002/bies.201400058 21 12 2 14 "Animals|ANP32A protein, human|Intracellular Signaling Peptides and Proteins|Nuclear Proteins|Nerve Tissue Proteins|Amino Acid Sequence" 7 ANP32C 24398589 Oncol. Rep. 2014 10.3892/or.2013.2956 3 7 0 14 "ANP32A protein, human|Intracellular Signaling Peptides and Proteins|Cell Nucleus|Cytoplasm|Nuclear Proteins|ELAV Proteins|Phosphoproteins|decay protein, Drosophila|Caspases|ELAV-Like Protein 1|Oncogenes|Genes, Tumor Suppressor|RNA, Messenger|Staurosporine|Drosophila Proteins" 7 C12orf4 25122211 PLoS ONE 2014 PMC4133367 10.1371/journal.pone.0104998 3 20 1 31 "Rats|Animals|Humans|*Cell Degranulation|*Rodent|Receptors, IgE|Mast Cells|Immunoglobulin E|Allergy|Signal Transduction|Cell Line, Tumor|Proteome|C12orf4 protein, human|Intracellular Signaling Peptides and Proteins" 7 C12orf57 24859618 Eur J Med Genet 2014 10.1016/j.ejmg.2014.05.002 53 2 1 46 *Anophthalmos|*Microphthalmos|*Coloboma|Eye Proteins|Mutation|Homeodomain Proteins|Transcription Factors|Phenotypes|SOXB1 Transcription Factors 7 C12orf57 24798461 Am. J. Med. Genet. 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J. 2014 10.1507/endocrj.ej14-0052 18 0 3 41 "Humans|*Non-alcoholic Fatty Liver Disease|*Metabolic Syndrome|Genome-Wide Association Study|Genetic Predisposition to Disease|Gene Frequency|Polymorphism, Single Nucleotide|Allele|Lipase|Alanine Aminotransferase|Genetic Association Studies|Genotype|Lysophospholipase|Membrane Proteins|Adaptor Proteins, Signal Transducing|Liver|*Phenotype|GCKR protein, human|TRIB1 protein, human" 7 DMRTC2 25082981 Mol. Hum. Reprod. 2014 10.1093/molehr/gau058 8 0 1 7 "Male|Female|Humans|Mice|Animals|*RNA Interference|*Transcription Factor 3|*Heterografts|*Transplantation, Heterologous|Mice, Nude|Oogonia|Ovaries|Meiosis|*Cell Differentiation|TCF3 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Germ Cells|Embryonic Germ Cells|Testis|Gene Expression Regulation, Developmental|Transcription Factors|Ovarian Follicle|mRNA" 7 FBXO39 24377578 Asian Pac. J. Cancer Prev. 2014 10.7314/apjcp.2013.14.11.6625 0 0 1 4 "Humans|Female|Male|*Testis|Carcinoma, Ductal, Breast|Fibroadenomas|*Oncogenes|Real-Time PCR, Quantitative|Gene Expression Regulation, Neoplastic|Antigens, Neoplasm|RNA, Messenger|Cell Line, Tumor|Downregulation|*Breast Neoplasms|FBXO39 protein, human|F-Box Proteins" 7 GPR149 25132237 Mol Ecol Resour 2014 10.1111/1755-0998.12311 19 0 4 1 "Swine|Animals|Humans|*Pigs, Domestic|*Color|Breeding|*Phenotype|Selection, Genetic|Quantitative Trait Locus|Domestication|Haplotype|*Reproduction|Chromosome Mapping|Genotype|Sequence Analysis, DNA|Polymorphism, Single Nucleotide|*Chinese|Asia|Europe" 7 IGSF5 24376456 Front Genet 2014 PMC3860258 10.3389/fgene.2013.00277 15 12 2 16 "Humans|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|*Blood Pressure|Hypertension|*Blood Pressure Determination|SNPs|Antihypertensive Agents|Systole|Phenotype|Diastole|Allele|Risk Factor|European Continental Ancestry Group|Arteries|Alcohol Consumption|CLEC3A protein, human|Lectins, C-Type|CRIPT protein, human|Adaptor Proteins, Signal Transducing" 7 LENEP 25457810 Mar. 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Genet. 2014 PMC3882731 10.1016/j.ajhg.2013.12.001 19 2 2 0 "Humans|*3' Untranslated Regions|*Down-Regulation|*Triglycerides|HEK293 Cells|*Binding Site|miRNA|Allele|Haplotype|Polymorphism, Single Nucleotide|Bioinformatic|Hypertriglyceridemia|Luciferase|APOA5 protein, human|Apolipoprotein A-V|MIRN485 microRNA, human" 7 RBM33 24520327 PLoS ONE 2014 PMC3919719 10.1371/journal.pone.0087208 14 18 4 77 "Humans|*Autistic Disorder|Autism Spectrum Disorder|Hedgehog Proteins|Haplotype|*Cerebellum|Genetic Predisposition to Disease|Homeodomain Proteins|Polymorphism, Single Nucleotide|Nerve Tissue Proteins|Genotype|Introns|Asian Continental Ancestry Group|Gene Expression Regulation|Transcription Factor" 7 SAMD7 24783520 Yao Xue Xue Bao 2014 3 1 0 26 "TGFB1 protein, human|*Transforming Growth Factor beta1|*Alveolar Epithelial Cells|*Artesunate|SMAD3 protein, human|Smad3 Protein|SMAD7 protein, human|Smad7 Protein|Epithelial-Mesenchymal Transition|*Idiopathic Pulmonary Fibrosis|Smad2 Protein|Cell Line|Pulmonary Alveoli|Epithelial Cells|Phosphorylation|Vimentin|Up-Regulation|*Mesenchymal Stem Cells" 7 SPEF1 25070955 J. 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Metab. 2012 10.1016/j.tem.2011.12.003 0 18 10 19 "Diabetes Mellitus, Type 2|Adiponectin|Adipokines|Insulin Resistance|Cytokines|TNF protein, human|Tumor Necrosis Factor-alpha|Resistin|Adipose Tissue|Insulin|Obesity|Inflammation|*Lymphotoxin-alpha" 7 COX6B2 23240874 Photomed Laser Surg 2012 10.1089/pho.2012.3369 11 0 1 7 "*Electron Transport|Electron Transport Complex IV|Electron Transport Complex I|Mitochondrial Proton-Translocating ATPases|Oxidative Phosphorylation|DNA, Mitochondrial|Mitochondria|Adenosine Triphosphate|Cells, Cultured|*Oxidation-Reduction|Fibroblasts|RNA, Messenger|*Central Nervous System Stimulants" 7 COX6B2 22941942 Reprod Sci 2012 10.1177/1933719112452939 8 0 0 7 "Male|Mice|Animals|*Reverse Transcriptase Polymerase Chain Reaction|*Transcriptome|*Spermatogenesis|Spermatids|Spermatogonia|Spermatocytes|*Laser Capture Microdissection|Testes|Messenger RNA|*Tissue Array Analysis|Western Blot|Proteins|Gene Expression Regulation, Developmental|Immunohistochemistry" 7 COX6B2 22234995 Physiol. Genomics 2012 10.1152/physiolgenomics.00072.2011 3 0 1 7 "Mice|Humans|Animals|*Glucose Intolerance|*Prognosis|COVID-19|severe acute respiratory syndrome coronavirus 2|Glucose Tolerance Test|Blood Glucose|Insulin Resistance|Diabetes Mellitus, Type 2|Dietary Fats|Biomarkers|Diet, High-Fat|ACSS2 protein, human|Acetate-CoA Ligase|Arfgap1 protein, mouse|GTPase-Activating Proteins" 7 DRGX 22394158 J Altern Complement Med 2012 PMC3306582 10.1089/acm.2010.0764 19 0 4 5 "Humans|*Genome-Wide Association Study|Republic of Korea|Medicine, Korean Traditional|Body Constitution|Asian Continental Ancestry Group|Phenotype|Risk Factors" 7 GIMAP2 23041938 Ann. Rheum. Dis. 2012 10.1136/annrheumdis-2011-200288 33 1 4 18 "Humans|*Genome-Wide Association Study|*Behcet Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Gene Frequency|Genotype|Case-Control Studies" 7 LENEP 23141580 Zhonghua Yan Ke Za Zhi 2012 0 0 0 7 "*Lens, Crystalline|Genes, Transgenic, Suicide|Thymidine Kinase|Ganciclovir|Lentivirus|Simplexvirus|Genetic Vectors|*Promoter Regions, Genetic|Genetic Therapy|Transfection|Antiviral Agents|Epithelial Cells|Green Fluorescent Proteins|*Lenses" 7 LENEP 22876133 Mol. Vis. 2012 PMC3413421 5 12 0 7 "Humans|*Bystander Effect|Thymidine Kinase|Ganciclovir|*Tretinoin|Genes, Transgenic, Suicide|*Epithelial Cells|Simplexvirus|Lentivirus|Lens, Crystalline|Genetic Vectors|*Promoter Regions, Genetic|Genetic Therapy|GJA1 protein, human|Connexin43|Antiviral Agents" 7 MAGEB16 22420508 Stem Cells Dev. 2012 10.1089/scd.2011.0637 11 0 2 2 Mice|Animals|*Transcriptome|*Embryonic Stem Cells|Germ Layers|*Cell Differentiation|Pluripotent Stem Cells|Octamer Transcription Factor-3|Nanog Homeobox Protein|Homeodomain Proteins|SOXB1 Transcription Factors|Blastocyst|Cell Lineage|Cell Line|Signal Transduction|siRNA|*Biological Processes 7 ODF3 23096689 Genet. Mol. Res. 2012 10.4238/2012.October.4.11 2 0 0 0 "Humans|Male|*Prostate|*Testis|*Prostate Cancer|*RNA Splicing|*Testicular Neoplasms|Splicings, Alternative|Seminal Plasma Proteins|RNA, Messenger|Amino Acid Sequence|Gene Expression Regulation, Neoplastic|Basal Cell Carcinoma|Cloning, Molecular|cDNA|Skin Neoplasms" 7 PCDHA6 23029284 PLoS ONE 2012 PMC3448685 10.1371/journal.pone.0045863 2 6 0 81 "Humans|*Polymorphism, Single Nucleotide|*miRNAs|*Monocytes|3' UTR|Genetic Predisposition to Disease|Genetic Association Studies|Gene Frequency|Alleles|Genotype|Binding Sites|*Gene Expression|Case-Control Studies" 7 PRPSAP1 23241142 BMC Genomics 2012 PMC3557156 10.1186/1471-2164-13-704 23 3 3 54 "Animals|*Chickens|*Abdominal Fat|Quantitative Trait Loci|Genome-Wide Association Study|Genomics|Haplotype|Polymorphism, Single Nucleotide" 7 RBM33 22484090 Microb. Pathog. 2012 PMC3512105 10.1016/j.micpath.2012.03.009 0 11 0 77 "Humans|Animals|*Brugia malayi|*Monocytes|pepsin B|*Pepsin A|Leukocytes, Mononuclear|Antigens, Helminth|*Apoptosis|Cytokines|Elephantiasis, Filarial|Helminth Proteins|IL10 protein, human|IL10|Antibodies, Helminth|Nitric Oxide|NOS2 protein, human|Nitric Oxide Synthase Type II|Tumor Necrosis Factor-alpha|Signal Transduction" 7 SAMD7 22619697 Oxid Med Cell Longev 2012 PMC3350848 10.1155/2012/619185 8 11 2 26 "Male|Rats|Animals|*Cardiotoxicity|*Tumor Suppressor Protein p53|*Deferoxamine|*Rats, Wistar|*Doxorubicin|Antibiotics, Antineoplastic|Reactive Oxygen Species|Apoptosis|Heart Diseases|Myocytes, Cardiac|Myocardium|Signal Transduction" 7 SLF2 23801440 Wiley Interdiscip Rev Dev Biol 2012 10.1002/wdev.10 5 0 0 26 "*Petunia|*RNase|*F-Box Proteins|*Inbreeding|Self-Incompatibility in Flowering Plants|Pollen|Flowers|Gene Expression Regulation, Plant|*Endoribonucleases|Plant Proteins|*Ribonuclease, Pancreatic|Plants, Genetically Modified" 7 TBC1D22A 22326833 Am. J. Pathol. 2012 PMC3657620 10.1016/j.ajpath.2011.12.021 29 0 2 43 "Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Gene Deletion|DNA Copy Number Variations|*Hepatocyte|Hepatectomies|Liver Regeneration|PTPRD protein, human|Receptor-Like Protein Tyrosine Phosphatases, Class 2|Gene Expression Regulation, Neoplastic|Cell Proliferation|DNA, Neoplasm|Transcription Factors|RSU1 protein, human|Rab1B protein, human|rab1 GTP-Binding Proteins|BAHCC1 protein, human|Proteins" 7 TEX28 22883432 BMC Med. Genet. 2012 PMC3575261 10.1186/1471-2350-13-71 5 2 2 28 7 tmem138 22936720 Mol. Biol. Evol. 2012 PMC3657383 10.1093/molbev/mss215 0 0 0 70 "Humans|Animals|*Vertebrates|*Biological Evolution|Fishes|Base Sequence|Evolution, Molecular|Multigene Family|Phylogeny|Conserved Sequence|*Genes, Regulator|Amino Acid Sequence|*Ciliopathy|Lamprey|Genomes|Amphibian|Mammals|Shark|TMEM138 protein, human|Membrane Proteins" 7 tmem138 22282472 Science 2012 PMC3671610 10.1126/science.1213506 27 2 2 70 "Animals|Humans|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|*Ciliopathy|Abnormalities, Multiple|Cerebellar Diseases|Cilia|Cerebellum|Retina|Membrane Proteins|Phenotypes|Mutation|Regulatory Sequences, Nucleic Acid|Genes, Regulator" 7 TTC29 22878202 Biosci. Biotechnol. Biochem. 2012 10.1271/bbb.120293 1 1 0 22 Male|Rats|Animals|*Follicle Stimulating Hormone|*Tetratricopeptide Repeat|Leydig Cells|Luteinizing Hormone|Pituitary Gland|Spermatogenesis|Testis|Sertoli Cells|Hypophysectomy|Spermatocytes|Testosterone|*Gene Expression|Chorionic Gonadotropin|Organ Size 7 C21orf91 22039568 J. Infect. Dis. 2011 PMC3203230 10.1093/infdis/jir633 13 0 0 51 "Humans|United States|*Herpes Labialis|*Herpes Simplex|Herpesvirus 1, Human|*Genotypes|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide" 7 C21orf91 21378095 Hum. Mol. Genet. 2011 PMC3090190 10.1093/hmg/ddr092 84 4 2 51 "Humans|*Blood Pressure|*African Americans|Genome-Wide Association Study|*Systole|European Continental Ancestry Group|Hypertension|Single Nucleotide Polymorphism|Genetic Loci|Genotypes|Phenotype|Diastole|Genetic Predisposition to Disease|Chromosome Mapping|ARRDC3 protein, human|Arrestins" 7 C6orf89 21857995 PLoS ONE 2011 PMC3153462 10.1371/journal.pone.0023072 1 4 0 113 "Humans|bombesin receptor subtype 3|*Receptors, Bombesin|HeLa Cells|*Epithelial Cells|Bronchi|Bombesin|Cell Proliferation|Western Blot|Green Fluorescent Proteins|Transfections|Cell Cycle|Lung|Microscopy, Fluorescence|Cytoplasm|Cloning, Molecular|BRAP protein, human|Ubiquitin-Protein Ligases" 7 CCDC25 22202459 Gastroenterology 2011 PMC3321110 10.1053/j.gastro.2011.12.039 127 13 10 32 "Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Disease Progression|Gene Expression Regulation, Neoplastic|Hep G2 Cells|RNA Interference|Adaptor Proteins, Signal Transducing|Cell Proliferation|Cell Line, Tumor|*Genomics|Kaplan-Meier Estimate|Signal Transduction" 7 COX6B2 21562175 J. Exp. Biol. 2011 10.1242/jeb.053322 3 0 0 7 "Animals|*Electron Transport Complex IV|*Muscle, Skeletal|*Gene Expression|Transcription Factors|Gene Expression Regulation|Acclimatization|Mitochondria|mRNA|Goldfish|Cold|Cell Nucleus|DNA, Mitochondrial|Zebrafish" 7 DDX50 21270226 J. Clin. Microbiol. 2011 PMC3122854 10.1128/JCM.01595-10 2 0 0 58 "Humans|*Mycobacterium bovis|*Urinary Bladder Neoplasms|*Urinary Bladder|*Bacillus|Administration, Intravesical|*Immunotherapy|Mycobacterium Infections|*DNA|Bacteremias|*Body Fluids" 7 FBXO39 21338577 Biochem. Biophys. Res. Commun. 2011 10.1016/j.bbrc.2011.02.077 8 0 0 4 "Humans|Male|Female|*Testis|Antigens, Neoplasm|*Colon Cancer|Neoplasm Proteins|cDNA Library|cDNA|Immunotherapy|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Hepatoma|RNA, Messenger|Liver Neoplasms|FBXO39 protein, human|F-Box Proteins" 7 GIMAP2 21686278 Small GTPases 2011 PMC3116615 10.4161/sgtp.2.1.14938 3 0 0 18 *GTPase|gephyrin|Membrane Proteins|G Proteins|Amino Acid Sequence|*Biochemical Phenomena|Guanine Nucleotides|Nucleotides|Guanosine Triphosphate 7 KCNQ1DN 22067257 Aging (Albany NY) 2011 PMC3229965 10.18632/aging.100395 65 1 7 8 "Humans|*Epigenetic|CpG Islands|DNA Methylation|Epigenesis, Genetic|*Aging|Genome, Human|DNA" 7 LHFPL4 21742057 Gene Expr. Patterns 2011 PMC3163734 10.1016/j.gep.2011.06.002 1 0 0 35 "Animals|*Zebrafish|Animals, Genetically Modified|Green Fluorescent Proteins|Enhancer Elements, Genetic|Genes, Reporter|Transgene|Gene Expression Regulation, Developmental|Promoter Regions, Genetic|In Situ Hybridization|Peripheral Nervous System|ACP5 protein, human|*Tartrate-Resistant Acid Phosphatase|DNA Transposable Elements|Ganglia" 7 LHFPL4 21742057 Gene Expr. Patterns 2011 PMC3163734 10.1016/j.gep.2011.06.002 1 0 0 35 "Animals|*Zebrafish|Animals, Genetically Modified|Green Fluorescent Proteins|Enhancer Elements, Genetic|Genes, Reporter|Transgene|Gene Expression Regulation, Developmental|Promoter Regions, Genetic|In Situ Hybridization|Peripheral Nervous System|ACP5 protein, human|*Tartrate-Resistant Acid Phosphatase|DNA Transposable Elements|Ganglia" 7 PLGLB1 21584744 J Orthop Sci 2011 10.1007/s00776-011-0091-x 1 4 0 30 "Mice|Humans|Animals|*Arthritis, Experimental|IgA receptor|*Plasminogen|Rheumatoid Arthritis|Synovial Membrane|*Neovascularization, Pathologic|Joints|Mice, Inbred DBA|Vascular Endothelial Growth Factor A|Cytokines" 7 PRPSAP1 21594610 Hum. Genet. 2011 10.1007/s00439-011-1006-9 0 2 0 54 "Humans|*Osteogenesis Imperfecta|*Hyperuricemia|Canada|*Mutation|Collagen Type I|Phenotype|Exons|Pedigree|RNA Splicing|Exomes|Missense Mutation|Haplotype|SNPs|SLC22A12 protein, human|Organic Anion Transporters|Organic Cation Transport Proteins" 7 RBM33 21745575 Protein Expr. Purif. 2011 10.1016/j.pep.2011.06.014 2 1 0 77 "Animals|Humans|*Brugia malayi|*Pepsin A|*Parasites|Renal Dialysis|*Lymphatic Filariasis|Recombinant Proteins|Inclusion Bodies|Escherichia coli|Cloning, Molecular|*Protease Inhibitors|Protein Folding|Size Exclusion Chromatography|Kinetics|Circular Dichroism|Electrophoresis, Polyacrylamide Gel|Hydrogen-Ion Concentration" 7 TBC1D22A 21738310 Bioinformation 2011 PMC3124795 10.6026/97320630006183 1 1 0 43 "Humans|*Globus Pallidus|MicroRNAs|RNA-Binding Proteins|*AIDS Dementia Complex|*HIV-2|*Encephalitis|*Microdissections|HIV-1|HIV Infections|Acquired Immunodeficiency Syndrome|*Neurons|Brain|*Chromosome 22|Profile, Gene Expression" 7 TEKT2 21519551 Anat Cell Biol 2011 PMC3080010 10.5115/acb.2011.44.1.69 14 1 0 24 "Animals|Mice|Hair Cells, Auditory|In Situ Hybridization|*Organogenesis|Gene Expression|Cell Differentiation|RNA, Messenger|Vestibule, Labyrinth|Atoh1 protein, mouse|Basic Helix-Loop-Helix Transcription Factors|Ttyh1 protein, mouse|Membrane Proteins|Atp6v1b1 protein, mouse|Vacuolar Proton-Translocating ATPases|Cdh23 protein, mouse|Cadherins|SPAG6 protein, mouse|Microtubule Proteins|Scn11a protein, mouse" 7 TGIF2LX 21316664 Fertil. Steril. 2011 10.1016/j.fertnstert.2011.01.018 10 0 3 15 "Humans|Female|Adult|*Primary Ovarian Insufficiency|*DNA Copy Number Variations|*Menopause, Premature|Chromosomes, Human, X|Comparative Genomic Hybridization" 7 ZNF536 21893220 Eur J Med Genet 2011 10.1016/j.ejmg.2011.08.001 4 0 1 14 "Humans|Female|Child|*Ataxia Telangiectasia|Cell Cycle Proteins|Tumor Suppressor Proteins|Ataxia Telangiectasia Mutated Proteins|DNA-Binding Proteins|Genes, cdc|Mutation|*Chromosome Structures|UQCRFS1 protein, human|Iron-Sulfur Proteins" 7 CHRAC1 21172662 Mol. Cell 2010 10.1016/j.molcel.2010.12.003 90 7 6 43 "Humans|*DNA Breaks, Double-Stranded|*DNA Repair|Ku Protein|SMARCA5 protein, human|Chromosomal Proteins, Non-Histone|DNA End-Joining Repair|Antigens, Nuclear|DNA-Binding Proteins|Adenosine Triphosphatases|*DNA|DNA Ligases|Chromatin Assembly and Disassembly" 7 DNAJC17 20872835 Inflamm. Bowel Dis. 2010 PMC3526817 10.1002/ibd.21479 11 1 0 19 "Humans|Mice|Animals|*Chromosomes, Human, Pair 2|*Mice, Inbred C57BL|*Colitis|glutathione peroxidase GPX1|*Glutathione Peroxidase|Ileocolitis|Inflammatory Bowel Disease|Mice, Knockout|Colon|Inflammation|Locus, Genetic|RNA, Messenger|Apoptosis|GPX2 protein, human" 7 DNAJC17 20160132 Endocrinology 2010 10.1210/en.2009-1240 6 0 0 19 "Humans|Mice|Animals|*Congenital Hypothyroidism|*Thyroid Gland|*Chromosomes, Human, Pair 2|*Genes, Essential|PAX8 protein, human|PAX8 Transcription Factor|NKX2-1 protein, human|Thyroid Nuclear Factor 1|Thyroid Dysgenesis|Paired Box Transcription Factors|Nuclear Proteins|Thyroglobulin|Heterozygote" 7 EMX2OS 20066053 PLoS ONE 2010 PMC2799550 10.1371/journal.pone.0008658 17 17 0 0 "Animals|Mice|Transcription Factor|Homeodomain Proteins|Gene Expression Regulation, Developmental|Neurons|Neurogenesis|Stem Cells|Cerebral Cortex|In Situ Hybridization" 7 GIMAP2 21059949 Proc. Natl. Acad. Sci. U.S.A. 2010 PMC2996681 10.1073/pnas.1010322107 27 1 3 18 "*Septins|Protein Conformation|Crystallography, X-Ray|Protein Structure, Tertiary|Dimerization|Guanosine Triphosphate|Binding Site|Models, Molecular|Dynamin|Hydrolysis|Nucleotides|Macromolecular Substances|Intracellular Membranes" 7 GIMAP2 20516611 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2010 PMC2882781 10.1107/S174430911001537X 4 2 0 18 "Humans|*Crystallization|*X-Rays|GTPases|Crystallography, X-Ray|Models, Molecular|Membrane Proteins|*Radiography|Nucleotides" 7 ODF3 20682177 Arch. Med. Res. 2010 10.1016/j.arcmed.2010.04.003 15 0 1 0 "Humans|Male|*Testis|*Prostate Cancer|Prostate-Specific Antigen|Prostatic Hyperplasia|Cancer Biomarkers|Antigens, Neoplasm|Neoplasm Proteins|Gene Expression Regulation, Neoplastic|RNA, Messenger|Specificity|SPATA19 protein, human|Mitochondrial Proteins|Seminal Plasma Proteins|LEMD1 protein, human" 7 RALGPS1 20053671 Hum. Mol. Genet. 2010 PMC2838533 10.1093/hmg/ddp585 106 0 9 15 "Animals|Mice|*RNA, Small Nucleolar|*Alternative Splicing|Prader-Willi Syndrome|Pre-mRNA|Exons|hnRNP|Brain|Cell Nucleolus|Gene Expression|PBRM1 protein, human|Nuclear Proteins|Bioinformatic|Transcription Factors" 7 TEKT2 20822404 Zool. Sci. 2010 10.2108/zsj.27.755 8 0 0 24 "Humans|Rats|Male|Animals|*Sperm Tail|Sperm Motility|tektins|Microtubule Proteins|Spermatozoa|Flagella|Axonemes|Microscopy, Immunoelectron|Cytoskeleton|Electron Microscopy|Amino Acid Sequence|Confocal Laser Scanning Microscopy|Immunoblotting" 7 WDR37 20383146 Nat. Genet. 2010 PMC2997674 10.1038/ng.568 332 0 25 57 "Humans|Genome-Wide Association Study|*Chronic Kidney Disease|Glomerular Filtration Rate|Creatinine|Kidney|CST3 protein, human|Cystatin C|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Kidney Failure, Chronic|PRKAG2 protein, human|AMP-Activated Protein Kinases|DACH1 protein, human|Eye Proteins|Transcription Factors|ALMS1 protein, human|Proteins" 7 B4GALNT4 20008118 Glycobiology 2009 10.1093/glycob/cwp197 30 0 2 25 "Humans|Male|kallikrein-related peptidase 3, human|*Prostate-Specific Antigen|*Prostatic Cancer|Benign Prostatic Hyperplasia|Kallikreins|Biomarkers, Tumor|*Glycosylation|Specificity|Lectins|Enzyme-Linked Immunosorbent Assay|Glycans" 7 C1QTNF8 19666007 Biochem. Biophys. Res. Commun. 2009 10.1016/j.bbrc.2009.08.014 20 1 2 19 "Humans|Male|Animals|Mice|*Complement C1q|Adiponectin|Protein Multimerization|Amino Acid Sequence|CTRP9 protein, mouse|Glycoproteins|CTRP1 protein, mouse|Adipokines" 7 CDH26 19824886 Allergy 2009 10.1111/j.1398-9995.2009.02091.x 0 0 0 16 "*Genetic Linkage|*Asthma|Hypersensitivity, Immediate|Receptors, IgE|Hypersensitivity|Immunoglobulin E|Phenotype|Chromosome Mapping" 7 CDH26 19116156 Int. J. Parasitol. 2009 10.1016/j.ijpara.2008.11.007 12 0 2 16 "Cattle|Animals|Male|*Trichostrongyloidea|Trichostrongyloidiasis|Parasite Egg Count|Cattle Diseases|*Intestine, Small|Feces|Eosinophils|Leukocyte Count" 7 DNAJC17 19878604 BMC Mol. Biol. 2009 PMC2774697 10.1186/1471-2199-10-100 17 0 2 19 "Pregnancy|Cattle|Animals|Female|*Real-Time Polymerase Chain Reaction|*Endometrium|*Gene Expression|Estrous Cycle|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation|Gene Expression Profiling|RNA, Messenger" 7 GPR149 19887567 Endocrinology 2009 PMC2803152 10.1210/en.2009-0760 11 0 1 1 "Female|Mice|Animals|Phylogeny|*Oocyte|GDF9 protein, human|GDF-9|Oogenesis|Granulosa Cells|Meiosis|Ovary|Ovulation|Fertility|FSH Receptor|Mice, Knockout" 7 KLHL31 19643178 Mech. Dev. 2009 10.1016/j.mod.2009.07.006 8 1 0 23 "Animals|*Muscle Development|Somites|Transcription Factor|Mesoderm|Wnt1 Protein|MyoD Protein|Wnt Proteins|DNA-Binding Proteins|Embryonic Induction|Trans-Activators|Muscle, Skeletal|Hedgehog Proteins|Muscle Proteins|Notochord|Gene Expression Regulation, Developmental|Cell Differentiation|Zebrafish Proteins|Neural Tube" 7 ODF3 19886887 Br. J. Dermatol. 2009 10.1111/j.1365-2133.2009.09568.x 11 0 2 0 "Male|Female|*Testis|*Basal Cell Carcinoma|Antigens, Neoplasm|Skin Neoplasms|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|*Neoplasms, Basal Cell|Immunotherapy" 7 RALGPS1 19393641 Dev. Biol. 2009 10.1016/j.ydbio.2009.04.017 31 0 0 15 "Animals|*Glomerular Filtration Barrier|*Zebrafish|*Reverse Genetics|Kidney Glomerulus|Podocytes|Zebrafish Proteins|Pronephros|Proteinuria|nephrin|Membrane Proteins|Morpholinos|Gene Knockdown|Glomerular Filtration Rate|Morphogenesis|Larvae|Permeability|crb2b protein, zebrafish" 7 SLC25A39 19914042 Epilepsy Res. 2009 10.1016/j.eplepsyres.2009.09.022 8 0 2 16 "Humans|Child|Lod Score|Genetic Linkage|*Epilepsy|Phenotypes|Chromosome Mapping|Genotype|Pedigree|Febrile Seizures|Genetic Predisposition to Disease|Epilepsy, Temporal Lobe|Microsatellite Repeats|*Chromosomes, Human, Pair 17" 7 SLC25A39 19656490 Cell Metab. 2009 PMC2745341 10.1016/j.cmet.2009.06.012 75 11 5 16 Mice|Animals|Iron-Sulfur Proteins|Mitochondrial Membrane Transport Proteins|Heme|Mitochondrial Proteins|Mitochondria|Anemia|Iron|Saccharomyces cerevisiae|Zebrafish|protoporphyrin IX|Protoporphyrins|Cytosol 7 thap9 20010837 Nat. Struct. Mol. Biol. 2009 PMC2933787 10.1038/nsmb.1742 34 2 1 6 "Humans|Animals|Drosophila melanogaster|Transposase|DNA-Binding Proteins|Zinc Fingers|Binding Sites|DNA Sequence|Protein Structure, Tertiary|TYRP1 protein, human|Amino Acid Sequence|Protein Binding|DNA Transposable Elements|*Membrane Glycoproteins|THAP1 protein, human|Nuclear Proteins|Apoptosis Regulatory Proteins" 7 ZFAND2B 19414486 Hum. Mol. Genet. 2009 PMC2706681 10.1093/hmg/ddp209 25 0 0 62 "Animals|Humans|*beta-Peptide, Amyloid|*Caenorhabditis elegans|*Alzheimer Disease|Caenorhabditis elegans Proteins|APP protein, human|*Amyloid beta-Protein Precursor|Peptide Fragments|MAGI2 protein, human|*Carrier Proteins|Animals, Genetically Modified|ATP dependent 26S protease|Proteasome|Protein Degradation|Disease Models, Animal|RNAi|Paralysis" 7 ZNF536 19398580 Mol. Cell. Biol. 2009 PMC2698762 10.1128/MCB.00362-09 15 6 0 14 "*Retinoic Acid|*Neurogenesis|*Transcription Factors|Cell Differentiation|Neurons|Receptors, Retinoic Acid|Nerve Tissue Proteins|Retinoic Acid Receptor alpha|PHF20 protein, human|*Brain|*Biomarkers, Tumor|Signal Transduction|Hippocampus|Transcription, Genetic|Zinc Fingers" 7 ACYP1 18314910 Genes Chromosomes Cancer 2008 10.1002/gcc.20551 39 0 5 12 "*Squamous Cell Carcinoma of Head and Neck|*DNA Copy Number Variations|Tongue Neoplasms|Gene Amplification|Laryngeal Neoplasms|Head and Neck Neoplasms|Carcinoma, Squamous Cell|Oligonucleotide Array Sequence Analysis|*Larynx|Gene Expression Profiling|Gene Dosage|Gene Expression Regulation, Neoplastic|DNA, Neoplasm|*Tongue|Neoplasm Proteins|Cell Line, Tumor|In Situ Hybridization, Fluorescence|Gene Expression" 7 CPNE5 18614158 Brain Res. 2008 10.1016/j.brainres.2008.05.051 2 0 0 63 "Animals|Mice|Neurons|NES protein, human|Nestin|In Situ Hybridization|Gene Expression Regulation, Developmental|Central Nervous System|Stem Cells|Brain|mRNA|Cell Differentiation|Immunohistochemistry|Western Blotting|Binding Proteins|CPNE5 protein, mouse" 7 DDX50 18615715 Proteins 2008 10.1002/prot.22138 4 0 0 58 "Humans|*DNA Helicases|RNA primers|Amino Acid Sequence|DEAD-box RNA Helicases|Double-Stranded RNA|Crystallography, X-Ray|*Guanidine|Models, Molecular" 7 DNAH3 18294281 Cancer Sci. 2008 10.1111/j.1349-7006.2008.00757.x 10 0 1 12 "Mice|Animals|*Mutagenesis, Insertional|*Colon|Genes, APC|*Epithelial Cell|*Mutation|Intestinal Mucosa|Cell Division|Genotype|*Retroviridae" 7 KLHL31 18719355 Mol. Cells 2008 4 4 0 23 "Chlorocebus aethiops|Humans|Mice|Animals|*Serum Response Element|*Protein A|HeLa Cells|*Activation, Transcriptional|*Response Element|Zinc Finger|*Heart|Repressor Proteins|Transcription Factor AP-1|Amino Acid Sequence|COS-7 Cells|MAP Kinase Signaling System|Sequence Homology, Amino Acid|Myocardium|Cell Nucleus|Signal Transduction" 7 LHFPL4 18381458 Cancer Res. 2008 10.1158/0008-5472.CAN-07-3194 0 0 1 35 "Humans|Female|*Uterine Cervical Neoplasms|CpG Islands|DNA Methylation|Genome, Human|Carcinoma, Squamous Cell|Deoxyribonucleases, Type II Site-Specific|Genomics" 7 LHFPL4 18381458 Cancer Res. 2008 10.1158/0008-5472.CAN-07-3194 22 0 1 35 "Humans|Female|*Uterine Cervical Neoplasms|CpG Islands|DNA Methylation|Genome, Human|Carcinoma, Squamous Cell|Deoxyribonucleases, Type II Site-Specific|Genomics" 7 TEX28 19098318 Invest. Ophthalmol. Vis. Sci. 2008 PMC3934550 10.1167/iovs.08-2455 7 3 1 28 7 TGIF2LX 18721782 J Genet Genomics 2008 10.1016/S1673-8527(08)60063-6 4 0 0 15 "Humans|Animals|*Drosophila|Proteins, Homeo Domain|Transcription Factors|Repressor Proteins|*Animals, Genetically Modified|IL10 protein, human|*Interleukin-10|Signal Transduction|Amino Acid Sequence|Prosencephalon|*Cell Cycle|Cell Lines|TGIF2 protein, human" 7 C6orf89 17461456 World J. Gastroenterol. 2007 PMC4146906 10.3748/wjg.v13.i10.1602 0 0 0 113 "Humans|*Hepatitis B virus|*Subtractive Hybridization Techniques|cDNA Library|Cloning, Molecular|Nucleic Acid Hybridization|Transcriptional Activation|RNA, Messenger" 7 LENEP 18062478 Environ Sci Pollut Res Int 2007 10.1065/espr2007.02.377 1 0 0 7 "*Biodegradation, Environmental|Brazil|Petroleum|Oil Spills|Geologic Sediments|Seawater|Water Pollutants, Chemical" 7 LIMD2 17699795 Cancer Res. 2007 10.1158/0008-5472.CAN-06-4771 13 0 0 47 "Humans|*Thyroid Cancer, Papillary|Neoplasm Recurrence, Local|*Lymphatic Metastasis|Thyroid Neoplasms|Carcinoma, Papillary|Proto-Oncogene Proteins B-raf|Immunohistochemistry|Gene Expression Regulation, Neoplastic|Quantitative Real Time PCR|Biomarkers, Tumor|Lymph Nodes" 7 LIMD2 17699795 Cancer Res. 2007 10.1158/0008-5472.CAN-06-4771 13 0 0 47 "Humans|*Thyroid Cancer, Papillary|Neoplasm Recurrence, Local|*Lymphatic Metastasis|Thyroid Neoplasms|Carcinoma, Papillary|Proto-Oncogene Proteins B-raf|Immunohistochemistry|Gene Expression Regulation, Neoplastic|Quantitative Real Time PCR|Biomarkers, Tumor|Lymph Nodes" 7 SAMD7 17347560 Am. 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Genet. 2006 10.1111/j.1365-2052.2006.01447.x 3 0 1 31 "Humans|Swine|Animals|*Radiation Hybrid Mapping|*Arthrogryposis|*Chromosomes, Human, Pair 5|Chromosome Mapping|Sus scrofa|Microsatellites|Genetic Marker|Chromosomes, Mammalian|SNPs|Sequence Analysis, DNA|Minnesota|DDX11 protein, human|DNA Helicases|DEAD-box RNA Helicases|PRICKLE1 protein, human|Tumor Suppressor Proteins|LIM Domain Proteins|C12orf4 protein, human" 7 DRGX 17045851 Gene Expr. Patterns 2006 10.1016/j.modgep.2006.09.003 2 0 0 5 "Animals|Mice|*Zebrafish|*Transcription Factor|Zebrafish Proteins|Hindbrain|Homeodomain Proteins|*Embryonic Development|Embryo, Nonmammalian|Mesencephalon|Gene Expression Regulation, Developmental|Spinal Cord|Nerve Tissue Proteins|Ganglia, Sensory|Embryo, Mammalian|Ganglia, Dorsal Root|Amino Acid Sequence|Sensory Neuron" 7 IGSF5 16982697 Mol. Cell. Biol. 2006 PMC1636774 10.1128/MCB.01502-06 5 0 0 16 "Male|Mice|Animals|*Cell Lineage|Igsf5 protein, mouse|Cell Adhesion Molecules|Hematopoietic Stem Cells|Cell Adhesion|Cell Differentiation|*Germ Cell|Membrane Proteins|Bone Marrow|Cell Communication|Plasma Membrane|Hematopoietic Stem Cell Transplantation" 7 IGSF5 16832352 Oncogene 2006 10.1038/sj.onc.1209468 13 2 4 16 "Chlorocebus aethiops|Animals|*Ligands|Membrane-Associated Guanylate Kinase|Cell Adhesion Molecules|Cell Adhesion|Tight Junction|PDZ Domain|Kidney Glomerulus|Cells, Epithelial|Protein Binding|Kidney|REG1A protein, human|*Lithostathine|COS Cells|Phosphorylation|HGF protein, human|Hepatocyte Growth Factor|Junctional Adhesion Molecules" 7 KCNQ1DN 17075716 Hum. Genet. 2006 10.1007/s00439-006-0283-1 6 0 2 8 "Humans|Fibromatosis, Gingival, Hereditary|*Fibromatosis, Gingival|*Maternal Inheritance|Lod Score|Genetic Linkage|Pedigree|Chromosome Mapping|Genes, Dominant|Exon|Genotype|Mutations|*Chromosome Structures|Phenotype|Intron|Haplotype|Chinese|*Family|Gingiva" 7 KLHDC2 16964437 Mol. Cell. Biochem. 2006 10.1007/s11010-006-9304-6 6 3 0 89 "Humans|Animals|*Kelch Repeat|Amino Acid Sequence|Sequence Alignment|Transcription Factor|Sequence Homology, Amino Acid|Carrier Proteins|Actin|Cell Nucleus|Microfilament Proteins|Drosophila Proteins|Gene Expression Regulation|Cell Line|Activation, Transcriptional|Humans|Animals|*Kelch Repeat|Amino Acid Sequence|Sequence Alignment|Transcription Factor|Sequence Homology, Amino Acid|Carrier Proteins|Actin|Cell Nucleus|Microfilament Proteins|Drosophila Proteins|Gene Expression Regulation|Cell Line|Activation, Transcriptional" 7 LENEP 16724094 Gene Ther. 2006 10.1038/sj.gt.3302790 3 0 0 7 "Humans|Animals|Rabbits|*Capsule Opacification|*Lens, Crystalline|Lens Capsule, Crystalline|*Gene Therapy|Cataract Extraction|CASP3 protein, human|Pro-Caspase-3|Epithelial Cells|Adenovirus|*B-Lymphocytes|*Eye Diseases|*Lenses" 7 LHFPL4 16752389 Hum. Mutat. 2006 10.1002/humu.20368 0 0 2 35 "Humans|Mice|Animals|Nonsyndromic Deafness|Deafness, Autosomal Recessive 66|Hearing Loss, Sensorineural|Deafness, Autosomal Recessive 67|Deafness, Autosomal Recessive 53|*Deafness|*Mutations|Genetic Linkage|Pedigree|Chromosome Mapping|Genes, Recessive|Homozygote|Genes, Dominant|DNA Mutational Analysis|Haplotype|Lipoma|Pakistan|LHFPL5 protein, human" 7 LHFPL4 16752389 Hum. Mutat. 2006 10.1002/humu.20368 23 0 2 35 "Humans|Mice|Animals|Nonsyndromic Deafness|Deafness, Autosomal Recessive 66|Hearing Loss, Sensorineural|Deafness, Autosomal Recessive 67|Deafness, Autosomal Recessive 53|*Deafness|*Mutations|Genetic Linkage|Pedigree|Chromosome Mapping|Genes, Recessive|Homozygote|Genes, Dominant|DNA Mutational Analysis|Haplotype|Lipoma|Pakistan|LHFPL5 protein, human" 7 MDS2 16643428 Br. J. 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Cell 2004 10.1016/s1097-2765(03)00523-9 20 6 0 43 "Humans|Animals|*Nucleosomes|*Chromatin Assembly and Disassembly|*Histones|Chromatin|Drosophila Proteins|Drosophila|Transcription Factors|Adenosine Triphosphatases|DNA|Amino Acid Sequence|*Helix-Loop-Helix Motifs|*Protein Domains|Gene Expression Regulation|Acf1 protein, Drosophila" 7 DMRTC2 15478606 Yi Chuan Xue Bao 2004 0 0 0 7 "Humans|Mice|Swine|Animals|*Ursidae|Phylogeny|Caenorhabditis elegans|Amino Acid Sequence|DNA|Transcription Factors|Intron|(S-dinitrophenyl)-6-mercaptopurine riboside triphosphate|*Thionucleosides|*Adenosine Triphosphate|Gonads|DNA Primers|Cloning, Molecular" 7 DRGX 14985445 J. 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Biol. 2003 PMC156145 10.1128/mcb.23.12.4267-4282.2003 41 0 2 16 "Animals|Chlorocebus aethiops|Cricetinae|*Tight Junctions|*Junctional Adhesion Molecule B|Cricetulus|Membrane-Associated Guanylate Kinase|MAGI1 protein, human|*Cell Adhesion Molecules, Neuronal|Cell Junctions|Nucleoside-Phosphate Kinase|Cell Adhesion Molecules|COS-7 Cells|Membrane Proteins|Cell Adhesion|Kidney Glomerulus|Cells, Epithelial|Binding Protein" 7 PLGLB1 14550287 Biochem. Biophys. Res. Commun. 2003 10.1016/j.bbrc.2003.09.089 2 2 0 30 "Humans|sphingosine 1-phosphate|*Angiogenesis Inhibitors|*Lysophospholipids|*Sphingosine|*Cell Migration|Neovascularization, Pathologic|Neovascularization, Physiologic|Signal Transduction|Vascular Endothelial Growth Factor A|Umbilical Veins|Endothelium, Vascular|Human Umbilical Vein Endothelial Cells|Cells, Cultured|Receptor Protein-Tyrosine Kinases" 7 PLGLB1 12799192 Exp. Cell Res. 2003 10.1016/s0014-4827(03)00137-x 2 8 0 30 "Humans|Mice|Animals|*Plasminogen|IgA receptor|Endothelial Cells|*Smooth Muscle Cells|Neovascularization, Pathologic|Angiostatin|Angiogenesis Inhibitors|Cell Migration|Muscle, Smooth, Vascular|Endothelium, Vascular|Cell Adhesion|Receptors, Vitronectin|Vascular Endothelial Growth Factor A|Neovascularization, Physiologic|Endostatin|Peptides|Cell Division|Peptide Fragments" 7 PLGLB1 12631627 Clin. 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Biophys. Res. Commun. 2018 10.1016/j.bbrc.2018.01.185 2 5 0 30 "Humans|Endothelial Cells|Carcinoma, Hepatocellular|HEK293 Cells|Liver Neoplasms|*Cell Differentiation|GPRC5C protein, human|*Receptors, G-Protein-Coupled|GPR182 protein, human|Liver|GATA4 protein, human|Transcription Factor GATA4|*Signal Transduction|Hepatocytes|*Biomarkers|Endothelium|Spleen" 6 KBTBD2 29331106 Eur. J. Immunol. 2018 10.1002/eji.201747281 2 3 0 35 "Mice|Animals|*Carcinoma, Hepatocellular|*Liver Neoplasms|*NK Cells|Cytotoxicity, Immunologic|Immunotherapy, Adoptive|*Signal Transduction|*Disease Models, Animal|*Antineoplastic Agents|Immunotherapy|*Downregulation|Lymphocyte Activation|Cell Line, Tumor|Adoptive Cell Transfer|Cell Proliferation|TOR Serine-Threonine Kinases" 6 LDLRAD3 29307994 World J. Gastroenterol. 2018 PMC5743505 10.3748/wjg.v23.i47.8345 29 1 0 10 "*RNA, Circular|*Pancreatic Cancer|Biomarkers, Tumor|Stomach Neoplasms|RNA|Gene Expression Regulation, Neoplastic|ROC Curve|Down-Regulation" 6 LUZP2 29850221 Int J Alzheimers Dis 2018 PMC5933020 10.1155/2018/2686045 1 15 0 39 "Humans|Aged|*Genetic Markers|Mental Status Schedule|Neuropsychological Tests|Cognitive Dysfunction|Cognition|Montreal Cognitive Assessment|Cognition Disorders|Alzheimer Disease|*Leucine Zipper|Russia|FBXO40 protein, human|F-Box Proteins" 6 LUZP2 29747637 BMC Med Genomics 2018 PMC5946407 10.1186/s12920-018-0364-8 4 1 0 39 *Genome-Wide Association Study|*Intermediate Filaments|Alzheimer disease type 1|Alzheimer Disease|Cognitive Dysfunction|Neurofilament Proteins|Disease Progression|Biomarkers|*Plasma|Cohort Studies 6 MAGED4B 30193086 Hum Vaccin Immunother 2018 PMC6363157 10.1080/21645515.2018.1520584 1 0 0 16 "Humans|Male|*Vaccines, Subunit|HLA-A2|Antigens, Neoplasm|Cancer Vaccines|T-Lymphocytes, Cytotoxic|*Head and Neck Cancer|*Peptides|Epitopes, T-Lymphocyte|*Vaccine Antigenicity|Neoplasm Proteins|Lymphocyte Activation|Squamous Cell Carcinoma of Head and Neck|Cell Line, Tumor|ELISPOT|Cytokines|Leukocytes, Mononuclear|FJX1 protein, human|Membrane Proteins" 6 MAGEE2 29492303 Environ Epigenet 2018 PMC5804541 10.1093/eep/dvx001 3 4 0 8 Humans|Male|*Pollutants|*DNA Methylation|CpG Islands|*Leukocytes|Polychlorinated Biphenyls|Environmental Pollution|Carcinogenesis 6 MIR873 29328486 Oncol. Rep. 2018 PMC5802030 10.3892/or.2018.6199 7 44 0 0 "Humans|*TNF Receptor-Associated Factor 5|*Colorectal Cancer|*Cell Proliferation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Prognosis|MicroRNAs|Biomarkers, Tumor|Cell Movement|Apoptosis|Cell Line, Tumor|*Colonic Neoplasms|Signal Transduction|Survival Rate|Downregulation|TAB1 protein, human|Adaptor Proteins, Signal Transducing|MIRN873 microRNA, human" 6 MXRA7 29781547 Exp. Dermatol. 2018 10.1111/exd.13687 0 1 0 118 "Humans|Mice|Animals|*Imiquimod|*Epidermis|*Psoriasis|Keratinocytes|Skin|*Disease Models, Animal|*Epidermal Cells|Interleukin-17|Aminoquinolines|Gene Expression|Dermis|RNA, Messenger|Proteins" 6 MXRA7 29720975 Front Immunol 2018 PMC5915751 10.3389/fimmu.2018.00773 2 52 0 118 "Mice|Animals|*Carbon Tetrachloride|Chemical and Drug Induced Liver Injury|*Liver|Mice, Inbred C57BL|Oxidative Stress|Signal Transduction" 6 NAP1L3 30046127 Sci Rep 2018 PMC6060140 10.1038/s41598-018-29518-z 0 8 0 27 "Humans|Mice|Animals|Epigenesis, Genetic|*Hematopoietic Stem Cell|*Cell Differentiation|Cell Proliferation|Transcription Factors|Genes, Homeobox|Gene Expression Regulation, Developmental|Cell Cycle Checkpoints|G0 Phase|Chromatin Assembly and Disassembly|Histone Chaperones" 6 NBPF3 30532766 Front Genet 2018 PMC6265481 10.3389/fgene.2018.00559 2 0 0 35 "*DNA Copy Number Variations|*Pulmonary Veins|*Scimitar Syndrome|Heart Defects, Congenital|Phenotype|Sequencing, Whole Exome|Case-Control Studies|Polymorphism, Single Nucleotide|Cohort Studies" 6 NBPF3 29688875 J Psychiatry Neurosci 2018 PMC5915240 2 0 0 35 "*Mendelian Randomization Analysis|*Pyridoxal|*Schizophrenia|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Case-Control Studies|Odds Ratio|Vitamin B 6|Risk Factors" 6 PLAC9 30291214 Biosci. Rep. 2018 PMC6239258 10.1042/BSR20180820 0 1 0 7 6 PMCHL1 30342662 Taiwan J Obstet Gynecol 2018 10.1016/j.tjog.2018.08.023 0 0 0 0 "Pregnancy|Female|Humans|*Prenatal Diagnosis|Amniocentesis|*Fetus|Karyotyping|*Heart Defects, Congenital|Comparative Genomic Hybridization|Ultrasonography, Prenatal|Chromosome Deletion|CDH10 protein, human|*Cadherins|Karyotype|In Situ Hybridization, Fluorescence|CDH18 protein, human|PRDM9 protein, human|Histone-Lysine N-Methyltransferase" 6 PRSS33 30508584 Ann. Allergy Asthma Immunol. 2018 10.1016/j.anai.2018.11.025 2 1 0 117 "Adult|Humans|Child|Child, Preschool|*Dermatitis, Atopic|*Transcriptome|*Eczema|*Skin|Th2 Cells|Th17 Cells|Gene Expression Profiling|Cytokines|Microarray Analysis" 6 prss37 30032357 Cell. Mol. 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Biol. 2018 10.1161/ATVBAHA.117.310594 4 4 0 13 "Humans|*Genome-Wide Association Study|Coronary Artery Disease|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Gene Frequency|Asian Continental Ancestry Group|Genetic Association Studies|Phenotype|Myocardial Infarction|Case-Control Studies|Odds Ratio|Risk Factors|Chi-Square Distribution" 6 SCML4 29472232 Arterioscler. Thromb. Vasc. 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Carcinog. 2017 10.1002/mc.22660 1 4 0 50 "Humans|*Carcinoma, Non-Small-Cell Lung|*Proto-Oncogene Proteins c-akt|*Phosphorylation|*Lung Neoplasms|Prognosis|CCND1 protein, human|Cyclin D1|Neoplasm Invasiveness|CDH1 protein, human|E Cadherin|Immunohistochemistry|Signal Transduction|Cell Proliferation|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Antigens, CD|Cell Movement|Lymphatic Metastasis" 6 MAGEE2 28516231 Mamm. Genome 2017 10.1007/s00335-017-9695-6 3 0 0 8 "Animals|*Phylogeny|*Mammals|*Evolution, Molecular|Syntenic Conservation|Xenarthra|Genome|BAGE protein, human|Antigens, Neoplasm|Sequence Alignment|Marsupialia|Amino Acid Sequence|MAGED1 protein, human|Exons|Opossum|Neoplasm Proteins|Eutherians" 6 MAGEE2 28487351 Endocr. Relat. Cancer 2017 PMC5488396 10.1530/ERC-17-0006 9 1 0 8 6 MXRA7 28847716 Gene 2017 10.1016/j.gene.2017.08.018 1 1 0 118 "Humans|Mice|Animals|*Mice, Inbred C57BL|Corneal Neovascularization|Corneas|BALB C Mice|Corneal Disease|Gene Expression|Neovascularization, Pathologic|mRNA|TIMP1 protein, human|TIMP-1|Wound Healing|MMP3 protein, human|Matrix Metalloproteinase 3|MMP13 protein, human|Matrix Metalloproteinase 13|*Data Mining|ECM1 protein, human|Extracellular Matrix Proteins" 6 PLAC9 29244159 Nephrol. Dial. Transplant. 2017 PMC5982720 10.1093/ndt/gfx304 2 0 0 7 "Humans|Mice|Animals|GPX3 protein, human|*Glutathione Peroxidase|*Ventricular Function, Left|*Coronary Vessels|*Chronic Kidney Disease|Knockout Mouse|*Coronary Thrombosis|Myocardium|Platelet Aggregation|Platelet|Reactive Oxygen Species|Cardiac Disease|Echocardiography|N,N-dimethylarginine|Arginine|*Protein-Energy Malnutrition" 6 PRSS33 28216055 Allergol Int 2017 10.1016/j.alit.2017.01.001 3 0 0 117 "Humans|*Eosinophils|*Serine Protease|*Serine Endopeptidases|*Leukocyte Count|Remodelling, Airway|Asthma|Cell Degranulation|Cytokines|Chemokines" 6 SCML4 28588211 Sci Rep 2017 PMC5460106 10.1038/s41598-017-02761-6 5 8 0 13 "Humans|Female|Animals|*Cancer Stem Cells|TWIST1 protein, human|Twist-Related Protein 1|SP140 protein, human|Transcription Factors|Cell Line, Tumor|Nuclear Proteins|PRRX1 protein, human|Homeodomain Proteins|Gene Expression Regulation, Neoplastic|Transcriptome Analysis|Phenotype|Heterografts|Signal Transduction|Disease Models, Animal|Gene Expression|Antigens, Nuclear" 6 SCML4 28588211 Sci Rep 2017 PMC5460106 10.1038/s41598-017-02761-6 5 8 0 13 "Humans|Female|Animals|*Cancer Stem Cells|TWIST1 protein, human|Twist-Related Protein 1|SP140 protein, human|Transcription Factors|Cell Line, Tumor|Nuclear Proteins|PRRX1 protein, human|Homeodomain Proteins|Gene Expression Regulation, Neoplastic|Transcriptome Analysis|Phenotype|Heterografts|Signal Transduction|Disease Models, Animal|Gene Expression|Antigens, Nuclear" 6 SIAH3 28784114 BMC Evol. 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Pediatr. Gastroenterol. Nutr. 2016 10.1097/MPG.0000000000001301 1 1 0 19 "Infant|Humans|*Iron|Colombia|Anemia, Iron-Deficiency|Feeding, Complementary|Ferritins|Hemoglobin|Risk Factors" 6 GPR182 27391260 Oncotarget 2016 PMC5342400 10.18632/oncotarget.10393 0 45 0 30 "Mice|Animals|*Adrenomedullin|Endothelial Cells|Phosphatidylinositol 3-Kinases|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Cancer|Cell Proliferation|Gene Expression Regulation, Neoplastic|Pancreas|Cell Movement|Mice, Nude|Signal Transduction|RNA Interference|Cell Line, Tumor|Up-Regulation|Apoptosis|Kaplan-Meier Estimate" 6 IFFO1 27312686 Laryngoscope 2016 10.1002/lary.26063 3 0 0 50 "*Keloid|*DNA Methylation|CpG Islands|*Genome|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Profiling|Case-Control Studies" 6 KBTBD2 27708159 Proc. Natl. Acad. Sci. U.S.A. 2016 PMC5081616 10.1073/pnas.1614467113 9 5 0 35 "Mice|Animals|*Insulin Resistance|B-insulin|*Insulin|*Diabetes Mellitus|Adipocytes|Adipose Tissue|Obesity|Fatty Liver|Blood Glucose|Phosphatidylinositol 3-Kinases|Metabolic Diseases|Mice, Knockout|Lipodystrophy|*Biotin|Diet" 6 LUZP2 27221037 Oncotarget 2016 PMC5122410 10.18632/oncotarget.9535 6 17 1 39 "Humans|Male|MDV 3100|AR protein, human|*Receptors, Androgen|*Prostatic Neoplasms, Castration-Resistant|*Phenylthiohydantoin|Androgen Antagonists|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|Xenograft Model Antitumor Assays|Signal Transduction|Downregulation|Apoptosis|*RNA|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO" 6 MAGEE2 26785681 Sci Rep 2016 PMC4726226 10.1038/srep19456 3 2 1 8 "Humans|Leukocytes, Mononuclear|*Whole Exome Sequencing|IL23R protein, human|Receptors, Interleukin|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Receptors, Interleukin-12|Behcet Syndrome|Asian Continental Ancestry Group|Case-Control Studies" 6 PFN4 27185630 Gene 2016 10.1016/j.gene.2016.05.023 3 3 0 11 "Male|Rats|Animals|*Profilins|*Isoforms|*Protein Structure, Secondary|Microfilament Proteins|Actins|Amino Acid Sequence|Testis|mRNA|Gene Expression Regulation" 6 prss37 27649891 Acta Biochim. Biophys. Sin. (Shanghai) 2016 10.1093/abbs/gmw096 1 1 0 13 "Male|Humans|Mice|Animals|*Infertility, Male|*Sperm|proacrosin|Akrosin|Acrosome|Acrosome Reaction|Spermatogenesis|Sperm Motility|Testis|Fertility|Zona Pellucida|Spermatids|Fertilization in Vitro|Enzyme Precursors|trypsin-like serine protease|Serine Endopeptidases|PRSS37 protein, human|Serine Proteases" 6 RNPEP 27775788 Eur Rev Med Pharmacol Sci 2016 0 9 0 254 "Mice|Animals|*Renin-Angiotensin System|*Bone Marrow|Renin|*Leukemia|Hematopoietic Stem Cells|Peptidyl-Dipeptidase A|Angiotensin II|Hematopoiesis|Receptor, Angiotensin, Type 2|RBPJ protein, human|Immunoglobulin J Recombination Signal Sequence-Binding Protein|Cell Differentiation|Signal Transduction|*Malignancies|B-Cell Leukemia|Tumor Microenvironment|ATP6AP2 protein, mouse|Proton-Translocating ATPases" 6 SCAF4 27582274 Curr. Genet. 2016 10.1007/s00294-016-0645-8 8 0 0 59 "*Polyadenylation|RNA Polymerase II|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|RNA Precursors|Yeast, Fission|mRNA Cleavage and Polyadenylation Factors|Poly A|*Protein Interaction Domain|RNA Stability|RNA, Messenger|*Gene Expression|Base Sequence" 6 SCAF4 27184836 Cell Rep 2016 PMC4893159 10.1016/j.celrep.2016.04.047 41 21 1 59 "Proteomics|cohesins|Cell Cycle Proteins|DNA Damage|DNA Repair|Ataxia Telangiectasia Mutated Proteins|Phosphorylation|Nuclear Proteins|Transcription, Genetic|Ultraviolet Rays|Proteasome Endopeptidase Complex|Protein Binding|Chromosomal Proteins, Non-Histone" 6 SCML4 27312686 Laryngoscope 2016 10.1002/lary.26063 3 0 0 13 "*Keloid|*DNA Methylation|CpG Islands|*Genome|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Profiling|Case-Control Studies" 6 SCML4 26990118 Laryngoscope 2016 10.1002/lary.25958 3 0 0 13 "*Keloid|CpG Islands|DNA Methylation|Promoter Regions, Genetic|*Head|*Neck" 6 SCML4 27312686 Laryngoscope 2016 10.1002/lary.26063 3 0 0 13 "*Keloid|*DNA Methylation|CpG Islands|*Genome|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Profiling|Case-Control Studies" 6 SCML4 26990118 Laryngoscope 2016 10.1002/lary.25958 3 0 0 13 "*Keloid|CpG Islands|DNA Methylation|Promoter Regions, Genetic|*Head|*Neck" 6 SCRT1 27094248 Genomics 2016 10.1016/j.ygeno.2016.04.001 10 0 0 122 "Humans|*Drug Resistant Epilepsy|*RNA-Seq|*Hippocampus|Epilepsy, Temporal Lobe|Transcriptome Analysis|*Whole Exome Sequencing|Sequencing, RNA|Neurons|KIF5A protein, human|Kinesin" 6 SIAH3 28005267 J. 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Cell 2015 PMC4551321 10.1091/mbc.E15-04-0245 13 4 1 44 "*Clathrin|Clathrin-Coated Vesicles|*Protein Transport|Adaptor Proteins, Vesicular Transport|SNARE|Carrier Proteins|Protein Binding|Endosomes" 6 C21orf59 25802884 Mol Genet Genomic Med 2015 PMC4367086 10.1002/mgg3.124 4 2 0 70 Humans|Male|*Jews|Kartagener Syndrome|Axonemal Dyneins|*Mutations|Cilia|Phenotypes|Situs Inversus 6 EBF4 25701644 Aging (Albany NY) 2015 PMC4359691 10.18632/aging.100715 35 0 6 19 "Female|Pregnancy|Humans|*DNA Methylation|*Down Syndrome|Phosphatidylinositol 3-Kinases|CpG Islands|Epigenesis, Genetic|*Blood Cells|Phenotype|TET1 protein, human|Mixed Function Oxygenases|Proto-Oncogene Proteins" 6 GCOM2 26677830 J Strength Cond Res 2015 10.1519/JSC.0000000000001294 5 0 0 1 Child|Humans|Strength Training|Muscle Strength|Physical Endurance|Oxygen Consumption|Exercise Test|Running|Cardiorespiratory Fitness|Exercise|School 6 KCTD20 25967398 J. Cell. Physiol. 2015 10.1002/jcp.25040 4 2 3 50 "Cattle|Animals|*Nucleus Pulposus|*Intervertebral Disk|*Osmolality|MAPK, p38|Phosphorylation|MAP Kinase Signaling System|Extracellular Signal-Regulated MAP Kinases|*Sodium-Potassium-Exchanging ATPase|Cell Cycle|Signal Transduction|Cell Proliferation|Osmosis|Cells, Cultured" 6 LRRC37A 26632684 Medicine (Baltimore) 2015 PMC5058953 10.1097/MD.0000000000001892 2 3 1 1 Humans|Aged|Genome-Wide Association Study|*Smell|Quality of Life|SNPs|Genetic Predisposition to Disease|European Continental Ancestry Group|Genotype|Parkinson Disease|tau Proteins|Alzheimer Disease|Aging 6 LRRC37A 25778476 Mol. Psychiatry 2015 PMC4573764 10.1038/mp.2015.23 72 5 3 1 *tau Proteins|*Alzheimer Disease|Genome-Wide Association Study|Apo E-4|Single Nucleotide Polymorphism|Genetic Predisposition to Disease|Genotype|Frontotemporal Dementia|Case-Control Studies|Quantitative Trait Loci|Risk Factors 6 LUZP2 25962659 Exp. Mol. Pathol. 2015 10.1016/j.yexmp.2015.05.005 1 0 0 39 "Adult|Humans|Pdgfra-Associated Chronic Eosinophilic Leukemia|Hypereosinophilic Syndrome|*Translocation, Genetic|FGFR1 protein, human|Fibroblast Growth Factor Receptor 1|Receptor, Platelet-Derived Growth Factor alpha|PDGFRB|mRNA Cleavage and Polyadenylation Factors|Imatinib Mesylate|Leukemia|Myeloproliferative Disorders|Benzamides|Cytogenetic Analysis|Piperazines|Pyrimidines|Oncogene Proteins, Fusion|In Situ Hybridization, Fluorescence|Cytogenetic Abnormalities" 6 MAGED4B 26060332 Dis. Markers 2015 PMC4427802 10.1155/2015/105358 11 0 4 16 "*Proteomics|*Cholangiocarcinoma|Bile Duct Neoplasms|Bile Ducts, Intrahepatic|CA-19-9 Antigen|Tumor Markers|Biliary Tract Neoplasms|Sensitivity and Specificity" 6 MIR873 26323558 Int. J. 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Genomics 2017 PMC5356355 10.1186/s40246-017-0101-y 7 5 0 13 "Child|Humans|*Mycoplasma pneumoniae|*Bronchoalveolar Lavage Fluid|*Pneumonia, Mycoplasma|*Immunologic Deficiency Syndromes|*Transcriptome Analysis|*Gene Expression" 5 MAGEF1 28516231 Mamm. Genome 2017 10.1007/s00335-017-9695-6 0 0 0 41 "Animals|*Phylogeny|*Mammals|*Evolution, Molecular|Syntenic Conservation|Xenarthra|Genome|BAGE protein, human|Antigens, Neoplasm|Sequence Alignment|Marsupialia|Amino Acid Sequence|MAGED1 protein, human|Exons|Opossum|Neoplasm Proteins|Eutherians" 5 MIR488 28765946 Mol Med Rep 2017 PMC5647003 10.3892/mmr.2017.7130 5 11 0 0 "Humans|*Histone|*Colorectal Cancer|Gene Expression Regulation, Neoplastic|Cell Migration|MicroRNAs|Cell Proliferation|RNA Interference|Cancer Biomarkers|Cell Line, Tumor|Oncogenes|Apoptosis|*Disease Progression|*Colonic Neoplasms|Cell Transformation, Neoplastic|Histone Demethylases|PHF8 protein, human|Transcription Factors|MIRN488 microRNA, human" 5 MIR874 29039607 Oncol. Rep. 2017 PMC5783584 10.3892/or.2017.6041 4 31 0 0 "*Down-Regulation|*Colorectal Cancer|*Signal Transduction|5 Fluorouracil|Gene Expression Regulation, Neoplastic|MicroRNAs|Drug Resistance, Neoplasm|Cell Proliferation|Cell Line, Tumor|Upregulation|Apoptosis|Xenograft Model Antitumor Assays|*Colonic Neoplasms" 5 NAA20 28380339 Structure 2017 10.1016/j.str.2017.03.003 14 0 0 53 "*NatB N-Terminal Acetyltransferase|*Acetylation|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|*Protein Processing, Post-Translational|Substrate Specificity|Acetyltransferases|Active Site|Peptides|NatB protein, S cerevisiae" 5 NBEAP1 28420514 Taiwan J Obstet Gynecol 2017 10.1016/j.tjog.2017.01.003 0 0 0 1 "Pregnancy|Female|Humans|Amniocentesis|*Fetus|Prenatal Diagnosis|Karyotyping|Trisomy|Comparative Genomic Hybridization|Mosaicism|Chromosome Deletion|In Situ Hybridization, Fluorescence|NBEAP1 protein, human|Neoplasm Proteins" 5 nkain1 28234981 PLoS ONE 2017 PMC5325534 10.1371/journal.pone.0172687 2 0 0 36 5 rgpd8 28254236 Taiwan J Obstet Gynecol 2017 10.1016/j.tjog.2016.12.003 0 0 0 25 "Female|Pregnancy|Humans|*Intellectual Disability|*Autism Spectrum Disorder|Chromosome Duplication|Comparative Genomic Hybridization|Abnormalities, Multiple|Nephronophthisis, familial juvenile|*Kidney Diseases, Cystic|Karyotyping|Amniocentesis|Ultrasonography, Prenatal|Liver|NPHP1 protein, human|Membrane Proteins|Adaptor Proteins, Signal Transducing|BUB1 protein, human|Protein-Serine-Threonine Kinases" 5 rgpd8 28236856 Med. 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Venereol. 2017 10.2340/00015555-2722 0 0 0 0 "Humans|*Complementarity Determining Region 3|*Mycosis Fungoides|*T Cell Receptor|CD1C protein, human|Antigens, CD1|Hair Follicle|CD1a antigen|Genes, T-Cell Receptor beta|Skin Neoplasms|*Lipids" 5 XRRA1 29082250 Biomed Res Int 2017 PMC5634579 10.1155/2017/5718968 3 44 0 62 "Humans|*X-Radiation|G2 Cell Cycle Arrest|Apoptosis|Cell Line, Tumor|*DNA Repair|*Colorectal Cancer|Ataxia Telangiectasia Mutated Proteins|DNA Damage|Checkpoint Kinase 1|Phosphorylation|Checkpoint Kinase 2|Protein Kinases|Ionizing Radiation|Radiation Tolerance|Signal Transduction|Cell Cycle Arrest|Cell Division|DNA-Binding Proteins" 5 ADPRHL1 27217161 Dev. Biol. 2016 PMC4990356 10.1016/j.ydbio.2016.05.006 8 12 1 25 "Animals|ADP-ribosylarginine hydrolase|*Hearts|Xenopus laevis|*Actin Filament|*N-Glycosyl Hydrolases|Xenopus Proteins|Myocardium|Gene Expression Regulation, Developmental|Sarcomere|Heart Ventricles|Myofibrillogenesis|Cell Differentiation|Morpholinos|Actin|Morphogenesis|Adprhl1 protein, Xenopus" 5 CASKIN2 27619958 BMC Struct. Biol. 2016 PMC5020537 10.1186/s12900-016-0065-5 2 1 1 44 "*src Homology Domains|polyproline|Peptides|Protein Binding|Amino Acid Sequence|Binding Sites|Adaptor Proteins, Signal Transducing|Nuclear Magnetic Resonance, Biomolecular|Models, Molecular|Signal Transduction|Nerve Tissue Proteins" 5 CASKIN2 27549312 Cell Commun. Signal 2016 PMC4994250 10.1186/s12964-016-0140-3 2 2 1 44 "*Sterile Alpha Motif|Adaptor Proteins, Signal Transducing|Protein Binding|Nerve Tissue Proteins|Models, Molecular|Signal Transduction|*Neurons|Kinase, Serine" 5 CDCP2 27251580 Neurogenetics 2016 PMC5063688 10.1007/s10048-016-0484-2 3 0 0 0 "Humans|Adult|*Prognosis|Anterior Temporal Lobectomy|*Seizure|Epilepsy, Temporal Lobe|Temporal Cortex|*Psychosurgery|*Stereotaxic Techniques|Amygdala|Hippocampus|Epilepsy|*Hemispherectomy|Electroencephalography|Treatment Outcome|*Split-Brain Procedure|*Craniotomy" 5 CNTD1 26920220 Elife 2016 PMC4805554 10.7554/eLife.12039 6 31 1 12 "Animals|*Synaptonemal Complex|Caenorhabditis elegans|*Meiosis|Caenorhabditis elegans Proteins|Crossing Over, Genetic|Chromosome Segregation|Meiotic Prophase I|Chromosomal Proteins, Non-Histone|*Mitogen-Activated Protein Kinases|Nuclear Proteins|Phosphorylation|Ect-2 protein, C elegans|Guanine Nucleotide Exchange Factors" 5 DHX40 27716579 Aquat. 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Psychiatry 2016 PMC7027938 10.1016/j.biopsych.2016.08.040 16 0 0 41 *Genome-Wide Association Study|*Attention Deficit Disorder with Hyperactivity|*Bipolar Disorder|Genetic Predisposition to Disease|Comorbidity|Phenotype 5 SLC22A14 27811987 Sci Rep 2016 PMC5095606 10.1038/srep36468 4 3 1 4 "Humans|Male|Mice|Animals|*Sperm Motility|Sperm|Infertility, Male|Spermatogenesis|Epididymis|Testis|Fertility|Germ Cells|Mice, Knockout" 5 slc6a16 27134767 Brain Behav 2016 PMC4842934 10.1002/brb3.462 8 3 1 9 "Genome-Wide Association Study|*Smoking|Tobacco Use Disorder|Genetic Predisposition to Disease|*Genome|*Tobacco Smoking|Polymorphism, Single Nucleotide|Genotype|*Disease Progression" 5 SPIN2B 27865410 Theriogenology 2016 10.1016/j.theriogenology.2016.09.047 7 1 0 23 "Humans|Male|*Testis|*Transcriptome|*Infertility, Male|Arrest of spermatogenesis|Azoospermia|Spermatogonia|Spermatogenesis|Sperm|Spermatocytes|Transcriptome Profiling|Meiosis|TSSK2 protein, human|Protein-Serine-Threonine Kinases|NLRP14 protein, human|Nucleoside-Triphosphatase|RNF212 protein, human|Ligases" 5 TM7SF3 27740623 Cell Death Differ. 2016 PMC5260493 10.1038/cdd.2016.108 5 10 0 50 "Humans|*Tumor Suppressor Protein p53|*Unfolded Protein Response|DDIT3 protein, human|Homologous Protein, C-EBP|Activating Transcription Factor 4|Endoplasmic Reticulum Stress|eIF-2 Kinase|Tunicamycin|CASP3 protein, human|Caspase 3|Eukaryotic Initiation Factor-2|Cell Death|IL1B protein, human|Interleukin 1 beta|Apoptosis|Thapsigargin|Signal Transduction|Cell Survival" 5 AKR1E2 26622071 Trans Am Ophthalmol Soc 2015 PMC4634221 10 0 0 17 "Child|Humans|United States|*Cataract|*Homozygote|*Phenotypes|*Mutation|Genes, Recessive|DNA Mutational Analysis|Pedigree|Genetic Association Studies|*Cohort Studies|*Ophthalmology" 5 BAGE2 26278209 ACS Appl Mater Interfaces 2015 10.1021/acsami.5b04910 0 0 0 1 "*Silver|*Nanostructures|Thermal Conductivity|Electrical Conductivity|Surface Properties|Tellurium|Particle Size|Temperature|Electrons|Glutaric Aciduria III|*Amino Acid Metabolism, Inborn Errors|BAGE protein, human|Materials Testing" 5 CSHL1 25563226 J Pers Med 2015 PMC4263976 10.3390/jpm4020282 5 6 2 442 "Humans|*Oxaliplatin|*Transcriptome|*Peripheral Neuropathy|Organoplatinum Compounds|Antineoplastic Agents|Colorectal Cancer|Neurotoxicity Syndromes|Colonic Neoplasms|*Biomarkers|*Leukocytes|SMIM1 protein, human|Membrane Proteins" 5 EFTUD1 26485663 J. 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Genome 2015 10.1007/s00335-015-9562-2 1 0 0 18 5 slc6a16 25750709 Biol Sex Differ 2015 PMC4352278 10.1186/s13293-015-0020-3 15 0 2 9 Humans|Female|Male|*Ethnic Groups|*Kidney|*Biological Transport|Membrane Transport Proteins|ATP-Binding Cassette Transporters|Liver|Gene Expression|Sex Differences|Real-Time Polymerase Chain Reaction 5 TMEM132B 25803036 PLoS ONE 2015 PMC4372548 10.1371/journal.pone.0121104 10 0 0 43 "Humans|*Whole Exome Sequencing|*Intracranial Aneurysm|Exome|Pedigree|Genetic Predisposition to Disease|Genetic Linkage|Studies, Genome-Wide Association|Genotype|Genetic Variation|Phenotype|Sequence Analysis, DNA|TMEM132B protein, human|Membrane Proteins" 5 CCDC78 25168790 Neurotherapeutics 2014 PMC4391390 10.1007/s13311-014-0300-3 20 0 1 4 "*Muscular Diseases|Sarcoplasmic Reticulum|Ryanodine Receptor Calcium Release Channel|Muscle, Skeletal|Excitation Contraction Coupling|Muscular Dystrophies|Mutation|Calcium" 5 CNTD1 24891606 J. 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Sci. 2014 10.1016/j.anireprosci.2014.11.007 0 1 0 6 "Humans|Horses|Male|Animals|*Testis|Sperm|Sperm Count|Spermatogenesis|Testosterone|Semen|*Germ Cells|Glucocorticoids|Cortisol|Dexamethasone|CATSPER1 protein, human|Calcium Channels" 5 DNAJC4 24857629 Theriogenology 2014 10.1016/j.theriogenology.2014.04.016 1 0 0 6 "Horses|Male|Animals|Cattle|Humans|ornithine decarboxylase antizyme|CYP19A1 protein, human|*Aromatase|estrogen receptor alpha, human|*Estrogen Receptor alpha|*Calcium Channel|*mRNA|*Sperm|Proteins|Semen|Semen Analysis|Fertility|Artificial Insemination" 5 DNAJC5B 25122905 J. 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Microbiol. 2014 10.1007/s12275-014-3694-z 1 0 1 53 "*Saccharomyces cerevisiae|*Catalytic Domain|*Acetylesterase|Saccharomyces cerevisiae Proteins|N-Terminal Acetyltransferase B|Acetyltransferases|Acetylation|Protein Transport|Synthetic Genes|Gene Deletion|Cell Cycle|NatB protein, S cerevisiae" 5 NBPF10 24967941 Gene 2014 10.1016/j.gene.2014.06.042 13 0 0 34 "*Glioblastoma|*Computational Biology|*Mitogen-Activated Protein Kinases|*Signal Transduction|Gene Regulatory Networks|*Cell Cycle|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|*Cell Division" 5 NBPF10 24395524 J. Pathol. 2014 PMC4013428 10.1002/path.4325 39 5 6 34 "Humans|Comparative Genomic Hybridization|Carcinoma, Ductal, Breast|Receptors, Estrogen|*Genomics|Biomarkers, Tumor|Mutations|Carcinoma, Papillary|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Phenotype|*Gene Expression|DNA Mutational Analysis|Breast Cancer|FAF1 protein, human|Adaptor Proteins, Signal Transducing" 5 NOP16 24837719 PLoS ONE 2014 PMC4023950 10.1371/journal.pone.0097362 8 11 0 59 "*Proteomics|*Euplotes|Electrophoresis, Gel, Two-Dimensional|*Ciliophora|Bioinformatics|Proteome|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|Protozoan Proteins|Gene Expression Regulation" 5 NOP16 24467952 BMC Plant Biol. 2014 PMC3914372 10.1186/1471-2229-14-37 0 7 1 59 "*Arabidopsis|*Germination|*Seed|*Transducin|*Biomass|Arabidopsis Proteins|Gene Expression Regulation, Plant|Abscisic Acid|Plant Growth Regulators|Plants, Genetically Modified|Transcription Factors|Signal Transduction|*Biological Phenomena|Ribosomes" 5 NOP16 24425784 Mol. Cancer Res. 2014 10.1158/1541-7786.MCR-13-0168 10 5 0 59 "Humans|RNA, Ribosomal|Cell Proliferation|Proto-Oncogene Proteins c-myc|Ribosomes|Cell Line, Tumor|Transcription, Genetic|Upregulation|Signal Transduction|Ribosomal Proteins|RNA, Small Interfering|Cell Transformation, Neoplastic|*Biological Phenomena" 5 SHISA7 25859288 Clin Epigenetics 2014 PMC4391300 10.1186/1868-7083-6-30 19 3 2 4 "*Carcinoma, Hepatocellular|*Hepatitis B virus|*Liver Neoplasms|*Cell Free DNA|Hepatitis B, Chronic|Liver Cirrhosis|DNA Methylation|Promoter Regions, Genetic|Biomarkers, Tumor|*Genetic Profile|DNA" 5 TRBJ2-1 24397960 J. Autoimmun. 2014 10.1016/j.jaut.2013.12.007 5 0 1 0 "Humans|musk|*T Cells|MUSK protein, human|Receptors, Cholinergic|*Myasthenia Gravis, MuSK|Fatty Acids, Monounsaturated|Receptor Protein-Tyrosine Kinases|HLA-DQ5 antigen|HLA-DQ Antigens|Allele|Gene Frequency|Antibodies|Genes, T-Cell Receptor beta|Genetic Predisposition to Disease|Humans|musk|*T Cells|MUSK protein, human|Receptors, Cholinergic|*Myasthenia Gravis, MuSK|Fatty Acids, Monounsaturated|Receptor Protein-Tyrosine Kinases|HLA-DQ5 antigen|HLA-DQ Antigens|Allele|Gene Frequency|Antibodies|Genes, T-Cell Receptor beta|Genetic Predisposition to Disease" 5 ADPRHL1 23849371 BMC Med. Genet. 2013 PMC3722009 10.1186/1471-2350-14-70 2 7 0 25 "Child|Humans|*Intellectual Disability|*Duplication, Chromosome|*Musculoskeletal Abnormalities|Developmental Disabilities|*Dystonia|Abnormalities, Multiple|*Dystonia, Secondary|Mutations|Chromosomes|THAP1 protein, human|DNA-Binding Proteins|Nuclear Proteins|Apoptosis Regulatory Proteins|Ciz1 protein, human" 5 AKR1E2 24239507 J. Steroid Biochem. Mol. Biol. 2013 10.1016/j.jsbmb.2013.11.001 9 0 2 17 Male|Humans|Swine|Animals|Androgens|Dihydrotestosterone|Steroids|16-androstene|Androstenes|Epiandrosterone|androst-16-en-3-one|Testis|Estrogens 5 AMZ1 30722242 Plant Dis. 2013 10.1094/PDIS-05-12-0507-PDN 0 0 0 30 Female|*Onions|*Garlic|*Fusarium|Argentina|Plant Diseases|Plant Leaves|Seedlings|Plant Roots|*Food Hypersensitivity|*Antioxidants|*Biological Products 5 BAGE2 23574628 Tissue Antigens 2013 10.1111/tan.12113 23 0 3 1 "Male|*Testis|*Cancer Stem Cells|MAGEA3 protein, human|Neoplasm Proteins|Antigens, Neoplasm|Side-Population Cells|MAGEA12 protein, human|*Oncogenes|KDM5B protein, human|Repressor Proteins|Cell Line, Tumor|Adenocarcinoma|CIC protein, human|Genes, Regulator|Lung Adenocarcinoma|Colonic Neoplasms|Immunotherapy|Nuclear Proteins" 5 CCDC78 24296417 Nat. Cell Biol. 2013 10.1038/ncb2892 10 0 1 4 *Centrioles|Centrosome|Cilia|Cell Cycle Proteins|Microtubule-Associated Proteins|Cell Cycle|Epithelial Cells 5 CCDC78 24075808 Dev. Cell 2013 PMC3816757 10.1016/j.devcel.2013.08.021 47 15 6 4 Humans|*Centrioles|Cilia|Cell Cycle Proteins|Protein-Serine-Threonine Kinases|Cell Cycle|Cell Division|HEK293 Cells 5 CNTD1 24080485 Gene 2013 10.1016/j.gene.2013.09.049 15 0 3 12 "Humans|*miRNAs|Signal Transduction|*Metals|Cancer|Gene Expression|CdCl2|RNA, Messenger" 5 EFTUD1 23497279 BMC Cancer 2013 PMC3637238 10.1186/1471-2407-13-119 14 7 0 112 "dihydroxy-vitamin D3|*Vitamin D|Calcitriol|Vitamins|Gene Expression Regulation, Neoplastic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Tumor Cells, Cultured" 5 FAM188B 23719187 J. Hum. Genet. 2013 10.1038/jhg.2013.59 8 0 1 19 Humans|Genome-Wide Association Study|Japan|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Genetic Loci|Case-Control Studies|Asian Continental Ancestry Group|Alleles|*Kidney Calculi|Genotype|Odds Ratio|*Epidemiologic Research Design|Risk Factors 5 FCRLB 23593433 PLoS ONE 2013 PMC3625155 10.1371/journal.pone.0061208 0 3 1 13 "Humans|*Glomerulonephritis, IGA|Genetic Predisposition to Disease|FCGR2B protein, human|*Receptors, IgG|Polymorphism, Single Nucleotide|Chinese|Gene Frequency|Genotype|Receptors, Fc|Case-Control Studies" 5 KLHDC1 23722832 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2013 PMC3668573 10.1107/S174430911301124X 8 2 0 3 "Humans|KEAP1 protein, human|*Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Kelch Repeat|*Ligands|Protein Binding|Intracellular Signaling Peptides and Proteins|Protein Conformation|Cullin Proteins|Protein Structure, Tertiary|Oxidative Stress|Ubiquitination|Binding Site|Adaptor Proteins, Signal Transducing|Models, Molecular|Peptides" 5 KLHDC1 23647822 Bioorg. Med. Chem. 2013 10.1016/j.bmc.2013.04.019 55 0 5 3 "KEAP1 protein, human|*Kelch-Like ECH-Associated Protein 1|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Kelch Repeat|*GA-Binding Protein Transcription Factor|Protein Binding|Small Molecule Libraries|Crystallography, Xray|Oxidative Stress|Intracellular Signaling Peptides and Proteins|Models, Molecular|Cysteine|Upregulation|Magnetic Resonance Spectroscopy" 5 MIR409 23360331 Br. J. Haematol. 2013 10.1111/bjh.12213 3 0 0 0 "Humans|*Purpura, Thrombocytopenic, Idiopathic|MicroRNAs|Leukocytes, Mononuclear|RNA-Binding Proteins|Messenger RNA|Bioinformatic|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression|Real Time Polymerase Chain Reaction|Autoimmunity|Up-Regulation|MIRN409 microRNA, human" 5 MIR488 23504987 Mol Nutr Food Res 2013 10.1002/mnfr.201200549 24 2 5 0 "*Tumor Microenvironment|pterostilbene|*Blueberry Plants|*Cancer Stem Cells|*Stilbenes|Epithelial-Mesenchymal Transition|*Neoplastic Processes|Cadherins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Cell Movement|Vimentin|MicroRNAs" 5 nkain1 23778322 Pharmacogenet. Genomics 2013 PMC4287355 10.1097/FPC.0b013e328362f9f2 6 1 0 36 "Humans|*Alcoholism|Genome-Wide Association Study|European Continental Ancestry Group|African Americans|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Allele Frequency|Risk Factors" 5 nkain1 23455491 Drug Alcohol Depend 2013 PMC3628730 10.1016/j.drugalcdep.2013.02.006 17 1 1 36 "Humans|Genome-Wide Association Study|*Alcoholism|European Continental Ancestry Group|Genetic Predisposition to Disease|African Americans|Polymorphism, Single Nucleotide|Case-Control Studies|*Risk Factors" 5 NOP16 24312670 PLoS ONE 2013 PMC3846774 10.1371/journal.pone.0082741 0 24 3 59 "Saccharomyces cerevisiae|60S Ribosomal Subunit|Saccharomyces cerevisiae Proteins|Ribosomal Proteins|RNA, Ribosomal|Ribosomes|RNA Precursors|snoRNP|Cell Nucleolus|Binding Protein|DEAD-box RNA Helicases|ATPase|Nuclear Proteins|Alleles|Mutation|EBP2 protein, S cerevisiae|Nsa1 protein, S cerevisiae|NOP4 protein, S cerevisiae" 5 PPP1R14D 23720309 Proc. 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Carcinog. 2012 10.1002/mc.21945 1 5 1 155 "Mice|Animals|Humans|*Binding Protein|Mice, Nude|*Cell Transformation, Neoplastic|*Tumorigenesis|*Cancers|Proto-Oncogene Proteins|Gene Expression Regulation, Neoplastic|Mice, Transgenic|NIH 3T3 Cells|Blotting, Northern|Promoter Regions, Genetic|Transfections" 5 CCDC78 22818856 Am. J. Hum. Genet. 2012 PMC3415545 10.1016/j.ajhg.2012.06.012 25 0 1 4 "Humans|Child|*Myopathy, Congenital|Myopathies, Structural, Congenital|*Mutation|Exome|Pedigree|Muscle Proteins|Muscle, Skeletal|Sequencing, Next-Generation|Genetic Linkage" 5 CDCP2 23159611 Biochem. Biophys. Res. Commun. 2012 10.1016/j.bbrc.2012.10.139 1 0 0 0 "*Arabidopsis|*Cystathionine|Arabidopsis Proteins|*Protein Domain|Protein Structure, Tertiary|TXN protein, human|Thioredoxin|*Nitric Oxide Synthase|Crystallography, X-Ray|Cystathionine beta-Synthase|Binding Sites|Amino Acid Sequence|Models, Molecular|Redox" 5 DDX31 23019224 Cancer Res. 2012 10.1158/0008-5472.CAN-12-1645 13 9 3 116 "Humans|*Carcinoma, Renal Cell|nucleophosmin|*Tumor Suppressor Protein p53|*Nuclear Proteins|Proto-Oncogene Proteins c-mdm2|*Transcription, Genetic|Cell Nucleolus|RNA, Ribosomal|RNA Interference|Cell Line, Tumor|Apoptosis|Ribosomes|Gene Expression Regulation, Neoplastic|Upregulation|Cell Proliferation|Cell Cycle Arrest|DEAD-box RNA Helicases|Kidney Neoplasms" 5 DNAJC5B 22666496 PLoS ONE 2012 PMC3364212 10.1371/journal.pone.0038240 7 9 0 1 Humans|Aged|*Pravastatin|*Genome-Wide Association Study|Prospective Studies|Statins|Coronary Heart Disease|Anticholesteremic Agents|Genotype|Single Nucleotide Polymorphisms|Allele|Cardiovascular Disease|Proportional Hazards Models|Scotland 5 FAM188B 22396660 PLoS Genet. 2012 PMC3291538 10.1371/journal.pgen.1002541 19 0 2 19 "Humans|*Genome-Wide Association Study|Japan|Genetic Predisposition to Disease|Genetic Loci|Polymorphism, Single Nucleotide|*Kidney Calculi|Asian Continental Ancestry Group|Case-Control Studies|Genotype|Odds Ratio|Glomerular Filtration Rate" 5 klhdc10 23102700 Mol. Cell 2012 10.1016/j.molcel.2012.09.018 24 8 3 152 "Animals|protein phosphatase 5|Hydrogen Peroxide|*Kelch Repeat|*Phosphoprotein Phosphatases|*Nuclear Proteins|Oxidative Stress|MAPK, p38|MAP Kinase Kinase Kinases|JNK Mitogen-Activated Protein Kinases|Enzyme Activation|Signal Transduction|Phosphorylation|Apoptosis|Protein Binding|Cell Death|Reactive Oxygen Species|Cell Line" 5 KLHL18 23213400 Biol Open 2012 PMC3507203 10.1242/bio.2011018 7 49 0 51 "AURKA protein, human|*Aurora Kinase A|Mitosis|Ubiquitin|Cullin Proteins|Centrosomes" 5 MAGEF1 25049512 Asian-australas. J. Anim. Sci. 2012 PMC4093042 10.5713/ajas.2012.12218 0 1 0 41 "Cattle|Animals|United States|Republic of Korea|*Phenotype|Quantitative Trait Loci|Chromosome Mapping|SNPs|Alleles|Genome-Wide Association Study|Markers, DNA|Microsatellite Repeats|Meat|Michigan" 5 NXNL2 22343139 Hum. Mol. Genet. 2012 PMC3664437 10.1093/hmg/dds050 6 0 0 2 "Mice|Animals|*Cell Survival|Retinal Cone Photoreceptor Cells|TXN protein, human|Thioredoxin|Retinal Rod Photoreceptor Cells|Retinal Degeneration|Retinitis Pigmentosa|Eye Proteins|Retina|Photoreceptor Cells, Vertebrate|Signal Transduction|*RNA Splicing|Oxidative Stress|RdCVF protein, mouse" 5 ZNF182 23269432 Mol. Cells 2012 PMC3887854 10.1007/s10059-013-2281-1 3 2 0 13 "tributyl phosphate|*Transcription Factors|*Zinc Finger|UBB protein, human|*Ubiquitin|*Protein Binding|SUMO-1 Protein|Transcription, Genetic|DNA-Binding Proteins|Sumoylation|Ubiquitin-Conjugating Enzyme E2|Repressor Proteins|Protein Processing, Post-Translational|Two-Hybrid System Techniques|Genes, Regulator|Cell Nucleus" 5 ZNF182 22634100 Gene 2012 10.1016/j.gene.2012.05.031 5 0 0 13 "Humans|Male|Child, Preschool|*Autistic Disorder|Genome-Wide Association Study|*Chromosome Banding|Mental Retardation, X-Linked|Chromosomes, Human, X|*Chromosome Structures|Mental Retardation|Zinc Finger|Chromosome Mapping|Mutations|Pedigree|Growth Disorders" 5 ARL14 21458045 Cell 2011 10.1016/j.cell.2011.03.023 44 4 2 83 Humans|*Antigen Presentation|*RNA Interference|*MHC Class II Molecules|Dendritic Cells|Protein Transport|Flow Cytometry|Myosin|Autoimmune Diseases 5 CASKIN2 21805519 Protein Sci. 2011 PMC3218363 10.1002/pro.703 27 0 4 44 "Humans|*Sterile Alpha Motif|Protein Structure, Tertiary|Protein Conformation|SAMD9 protein, human|Proteins|Models, Molecular|Amino Acid Sequence|Polymerization|Polymers|CASKIN2 protein, human|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing|ANKS3 protein, human|Carrier Proteins" 5 CDCP2 22021414 Plant Cell 2011 PMC3229136 10.1105/tpc.111.089847 23 1 3 0 "*Arabidopsis|*Cystathionine|Hydrogen Peroxide|TXN protein, human|*Thioredoxin|Arabidopsis Proteins|Chloroplast|TYRP1 protein, human|*Oxidoreductases|Photosynthesis|Redox|*Membrane Glycoproteins|*Nitric Oxide Synthase|NADP" 5 NOP16 21863248 Transgenic Res. 2011 PMC4043839 10.1007/s11248-011-9529-3 0 3 1 59 "Humans|Mice|Animals|*Mammary Neoplasms, Animal|*Genes, myc|Proto-Oncogene Proteins c-myc|estrophilin|Receptors, Estrogen|Mammary Neoplasms, Experimental|Mice, Transgenic|Mammary Glands, Animal|Estrogens|Transforming Growth Factor alpha|Gene Expression Regulation, Neoplastic|Carrier Proteins|Epithelial Cells" 5 NXNL2 22185426 BMC Ophthalmol 2011 PMC3271040 10.1186/1471-2415-11-38 6 0 0 2 "Humans|Animals|*Retinal Cone Photoreceptor Cells|*Rodent|*Retinitis Pigmentosa|Retinal Rod Photoreceptor Cells|Retinal Degeneration|Retina|Photoreceptor Cells, Vertebrate|Eye Proteins|Thioredoxins|Cell Count|Cell Survival" 5 SCFD2 21713766 Cancer 2011 10.1002/cncr.26276 16 0 1 18 5 slc6a16 21885739 Proc. 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Immunol. 2010 PMC2995445 10.1016/j.cellimm.2010.08.007 5 1 2 13 "Mice|Animals|FCGR2B protein, human|*Receptors, IgG|B Cells|Mice, Inbred Strains|Promoter Regions, Genetic|Allele|Responses, Antibody|Lymphocyte Activation|Polymorphism, Genetic|Upregulation|*Phenotype" 5 NXNL2 20949100 PLoS ONE 2010 PMC2951342 10.1371/journal.pone.0013075 4 4 0 2 "*Photoreceptor Cells, Vertebrate|Retina|Homeodomain Proteins|Retinal Rod Photoreceptor Cells|Photoreceptor, Cone|Trans-Activators|Eye Proteins|Promoter Regions, Genetic|nucleoredoxin|Nuclear Proteins|Gene Expression Regulation|Protein Binding|Oxidoreductases" 5 PPP1R14D 21112318 Brain Res. 2010 10.1016/j.brainres.2010.11.066 3 0 0 12 "Animals|Rats|*Proteome|Diabetes Mellitus, Experimental|Proteomics|Alloxan|Electrophoresis, Gel, Two-Dimensional|Hypoglycemic Agents|Phytotherapy|Cynodon|Rats, Wistar|Plant Extracts|Blood Glucose|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization|*Brain|Rab18 protein, rat|rab GTP-Binding Proteins" 5 TMEM185A 20969748 BMC Cancer 2010 PMC2974737 10.1186/1471-2407-10-576 37 3 4 64 "Humans|Female|Cystadenocarcinoma, Serous|Ovarian Cancer|*Carcinoma, Ovarian Epithelial|Prognosis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Survival Analysis|Kaplan-Meier Estimate" 5 DNAJC4 19496026 Cell Stress Chaperones 2009 PMC2866972 10.1007/s12192-009-0121-1 12 0 1 6 "Humans|*Systemic Inflammatory Response Syndrome|*Temperature|*Sepsis|*Fever|Heat Shock Proteins|Oligonucleotide Array Sequence Analysis|Innate Immune Responses|Inflammation|lipopolysaccharide-binding protein|Acute-Phase Proteins|Signal Transduction|Heat Shock Transcription Factor 1|Heat-Shock Proteins 70|Transcription Factors|Critical Care|Membrane Glycoproteins|DNAJB12 protein, human|HSP40 Heat-Shock Proteins" 5 KLHL18 19698110 BMC Cancer 2009 PMC3087337 10.1186/1471-2407-9-290 41 5 6 51 "Humans|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Genes, Tumor Suppressor|Neoplasm Staging|RNA, Messenger|CCDC12 protein, human|Proteins" 5 KLHL18 19624754 Genes Cells 2009 10.1111/j.1365-2443.2009.01323.x 4 0 1 51 "Cullin Protein|parkin protein|E3 Ubiquitin Ligase|Ubiquitination|Ubiquitin|Protein Binding|Drosophila Proteins|TYRP1 protein, human|*Membrane Glycoproteins|BTB Domain|*Cytoplasm|Adaptor Proteins, Signal Transducing|Protein Interaction Domains and Motifs|Amino Acid Sequence" 5 PPP1R14D 19846560 J. 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Immun. 2019 PMC6752960 10.1016/j.bbi.2019.04.039 1 0 0 29 "Humans|*Stress Disorders, Post-Traumatic|*Syndrome|*Military Personnel|*Transcriptome|Depression|*Transcriptome Analysis|Comorbidity|ESCO1 protein, human|Acetyltransferases|RBaK protein, human|Repressor Proteins|ZNF644 protein, human|Transcription Factors|CREBZF protein, human|Basic-Leucine Zipper Transcription Factors" 4 ANKRD16 31426789 BMC Med Genomics 2019 PMC6700823 10.1186/s12920-019-0568-6 1 0 0 1 "Humans|*Genome-Wide Association Study|*Glomerulonephritis, IGA|Republic of Korea|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Asian Continental Ancestry Group|Gene Frequency|Case-Control Studies|Genetic Loci|Risk Factors" 4 BPIFB3 31316551 Front Genet 2019 PMC6611142 10.3389/fgene.2019.00612 0 1 0 15 "Animals|*Alleles|*Chickens|Genome-Wide Association Study|*Comb|*Genomics|Breeding|Egg Shell|Phenotype|BMP7 protein, human|*Bone Morphogenetic Protein 7|Quantitative Trait Loci|*Eggs|*Color|Genetic Linkage|Polymorphism, Single Nucleotide|China" 4 C10orf76 31829496 EMBO Rep. 2019 PMC7001497 10.15252/embr.201948441 1 5 0 90 "*Enterovirus|*Golgi Apparatus|*Enterovirus Infections|Kobuvirus|Virus Replication|phosphatidylinositol 4-phosphate|Phosphatidylinositol Phosphates|Protein Binding|Picornaviruses|Viral Proteins|Membrane Proteins|Adaptor Proteins, Signal Transducing|Phosphotransferases (Alcohol Group Acceptor)" 4 C10orf76 31519766 Mol. Cell Proteomics 2019 PMC6823846 10.1074/mcp.RA119.001645 1 1 0 90 "Humans|*Binding Protein|*Golgi Apparatus|Coat Protein Complex I|Intracellular Membranes|ADP-Ribosylation Factors|Endoplasmic Reticulum|Guanine Nucleotide Exchange Factors|Protein Transport|HeLa Cells|Protein Binding|GBF1 protein, human" 4 C2orf80 31842352 Cancers (Basel) 2019 PMC6966482 10.3390/cancers11122001 0 0 0 2 "Genome-Wide Association Study|Glioma|Isocitrate Dehydrogenase|Brain Neoplasms|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Mutation|*Risk Factors|Biomarkers, Tumor|Genetic Loci|Case-Control Studies" 4 CCDC171 31745258 Int J Obes (Lond) 2019 10.1038/s41366-019-0488-8 0 0 0 27 4 CCNI2 31661127 Mol Med Rep 2019 10.3892/mmr.2019.10771 0 0 0 21 "Humans|*Carcinoma, Hepatocellular|*Prognosis|*Liver Neoplasms|Gene Expression Regulation, Neoplastic|Gene Ontology|Biomarkers, Tumor|Gene Expression Profiling|Bioinformatic|Databases, Genetic|Kaplan-Meier Estimate|Gene Regulatory Networks|Receiver Operating Characteristic|Survival Rate" 4 CCNI2 30598658 Clin Proteomics 2019 PMC6302491 10.1186/s12014-018-9215-z 5 0 0 21 "Humans|Female|Liquid Chromatography|*Carcinoma, Ovarian Epithelial|*Peptides|Spectrometry, Mass, Electrospray Ionization|Tandem Mass Spectrometry|Proteomics|Proteins|*Ovarian Cancer|*Plasma|Algorithms" 4 DHRS11 30926317 Chem. 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Rep. 2019 PMC6365692 10.3892/or.2019.6969 0 8 0 1 "Humans|*Colon Cancer|MicroRNAs|Cell Migration|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|3' Untranslated Region|Downregulation|Cell Proliferation|mRNA|Up-Regulation|Cell Line, Tumor|Oncogenes|Prognosis|Colon|*Rectal Neoplasms" 4 MTRNR2L2 31753007 BMC Res Notes 2019 PMC6873426 10.1186/s13104-019-4807-x 0 0 0 101 "Humans|*Coronary Artery Disease|humanin|Intracellular Signaling Peptides and Proteins|Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Loci|Phenotype|European Continental Ancestry Group|Risk Factors|Genomics|*Protein Isoforms" 4 MTRNR2L2 31611907 Front Genet 2019 PMC6777643 10.3389/fgene.2019.00885 0 0 0 101 "Mice|Animals|glyphosate|*Epigenome|*Cell Transformation, Neoplastic|*Tumorigenesis|DNA Methylation|dimethyloxallyl glycine|*Glycine|Promoter Regions, Genetic|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|MicroRNAs|5 Methylcytosine|Cell Line, Tumor|Tamoxifen|*B Cells|Mixed Function Oxygenases|Tet3 protein, mouse|DNA-Binding Proteins" 4 OVCH2 31311989 Sci Rep 2019 PMC6635495 10.1038/s41598-019-46807-3 1 0 0 4 4 PCDHAC2 31088413 BMC Cancer 2019 PMC6518703 10.1186/s12885-019-5616-2 1 5 0 50 "Humans|Genome-Wide Association Study|*Carcinoma, Pancreatic Ductal|Pancreatic Carcinoma|*Pancreatic Neoplasms|Promoter Regions, Genetic|DNA Methylation|Epigenesis, Genetic|Prognosis|Gene Expression Regulation, Neoplastic|Cadherins|Biomarkers, Tumor|PCDH10 protein, human" 4 PCDHAC2 31083674 PLoS ONE 2019 PMC6513083 10.1371/journal.pone.0216795 0 0 0 50 "Humans|Female|Pregnancy|Mice|Animals|*Endothelial Cells|*Fetus|*Lungs|Gene Expression Profiling|Signal Transduction|Gene Expression Regulation, Developmental|*Prenatal Care|Upregulation|Innate Immune Response" 4 PHYHIPL 30962415 Med. 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Immunol. 2018 PMC6941595 10.1016/j.clim.2018.04.009 1 3 0 0 Humans|*Th17 Cells|*Single-Cell Analysis|Th1 Cells|Interleukin-17|Sjogren's Syndrome|Interferon-gamma|T Cell Receptor 4 C11orf31 28210221 Front Pharmacol 2017 PMC5288649 10.3389/fphar.2017.00038 2 23 0 104 4 C9orf142 28394347 Oncogene 2017 PMC5562846 10.1038/onc.2017.60 10 22 0 77 4 CCNI2 28112194 Sci Rep 2017 PMC5256034 10.1038/srep40979 8 36 0 21 "CDK5 protein, human|*Cyclin-Dependent Kinase 5|*Cyclin I|*Cyclin B1|Phosphorylation|*Cell Cycle Checkpoints|Signal Transduction|Cell Cycle|Nerve Tissue Proteins|Cell Nucleus|Cell Proliferation" 4 CSNK1G3 29177465 Hum. Mol. 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Bowel Dis. 2017 10.1097/MIB.0000000000001066 10 0 0 2 "Humans|*Crohn Disease|*Transcriptome|*Intestinal Mucosa|Colitis, Ulcerative|*Sequencing, RNA|*Base Sequence|RNA, Messenger|*Whole Exome Sequencing" 4 GPR141 28076348 PLoS Genet. 2017 PMC5226683 10.1371/journal.pgen.1006516 15 10 0 30 "Humans|*Autism Spectrum Disorder|*Epistasis, Genetic|Genome-Wide Association Study|SNPs|Genotype|Phenotype|MAP Kinase Signaling System" 4 KBTBD4 28726821 Nature 2017 PMC5905700 10.1038/nature22973 137 3 0 21 "Humans|Child|*Medulloblastoma|Cerebellar Neoplasms|Transcription Factors|Nuclear Proteins|Hedgehog Proteins|Mutations|Genomics|Genome, Human|Oncogenes|beta Catenin|DNA Methylation|Cohort Studies" 4 KIAA1210 28203736 Biol. Reprod. 2017 PMC5819839 10.1095/biolreprod.116.145458 2 1 0 52 Humans|Male|*Acrosome|*Testis|Proteomics|Spermatids|Spermatogenesis|Spermatocyte|link protein|*Proteoglycans|*Extracellular Matrix Proteins|*X Chromosome|Membrane Protein|Cell Junctions|Adherens Junctions|*Inferior Colliculi|*Cytoplasm 4 KIAA1549L 29192581 Twin Res Hum Genet 2017 PMC6013261 10.1017/thg.2017.62 3 1 0 35 "Humans|Young Adult|*Bipolar Disorder|Genome-Wide Association Study|Depressive Disorder, Major|*Mexican Americans|*Indians, North American|Multifactorial Inheritance|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Attempted Suicide|Schizophrenia|Case-Control Studies|Risk Factors" 4 KIAA1549L 28270869 Clin Epigenetics 2017 PMC5335821 10.1186/s13148-017-0322-x 9 4 0 35 "*DNA Methylation|*Epigenome|Early Detection of Cancer|*Colorectal Cancer|CpG Islands|*Markers, DNA|*Screening|Biomarkers, Tumor|Promoter Regions, Genetic|Prognosis|Epigenesis, Genetic|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|*Leukocytes" 4 LINC00176 28869604 Oncogene 2017 10.1038/onc.2017.312 22 5 0 0 "*Carcinoma, Hepatocellular|*RNA, Long Noncoding|*Liver Neoplasms|*Cell Survival|MIRN92 microRNA, human|*MicroRNAs|*Genes, Tumor Suppressor|Gene Expression Regulation, Neoplastic|Downregulation|Upregulation|Cell Movement|Cell Proliferation|mRNA|*Cell Cycle|Cell Line, Tumor" 4 LINC00959 29228592 Oncotarget 2017 PMC5722544 10.18632/oncotarget.21171 4 20 0 0 "Humans|*RNA, Long Noncoding|*Prognosis|*Colorectal Cancer|Neoplasm Invasiveness|*Colonic Neoplasms|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Movement|Cell Line, Tumor|Down-Regulation|*Neoplastic Processes|Tumorigenesis|Lymphatic Metastasis" 4 METTL11B 29050564 J. 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Res. 2017 PMC5636198 10.1161/CIRCRESAHA.117.311607 10 7 0 45 "*Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels|*Bradycardia|*Sick Sinus Syndrome|Potassium Channels|Sinoatrial Node|Gated Channel, Cyclic-Nucleotide|*Arrhythmias, Cardiac|Muscle Proteins|*Exercise Training|Ion Transport|Downregulation|MicroRNAs" 4 OVCH2 28569245 J. 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Ther. 2017 PMC5899062 10.1002/cpt.907 2 42 0 48 "Humans|Male|*Steroid 17-alpha-Hydroxylase|abiraterone|*Prostatic Neoplasms, Castration-Resistant|*Cytochrome P-450 CYP3A|Prospective Studies|Abiraterone Acetate|*Androstenes|Prednisone|Androgen Antagonists|Antineoplastic Agents, Hormonal|Cytochrome P-450 Enzyme Inhibitors|Disease-Free Survival|Kaplan-Meier Estimate|Antineoplastic Combined Chemotherapy Protocols|CYP3A4 protein, human|CYP17A1 protein, human|TSPYL1 protein, human|Nuclear Proteins" 4 ANKRD13A 26797118 J. Biol. Chem. 2016 PMC4813590 10.1074/jbc.M115.710707 8 5 1 58 "VCP protein, human|*Valosin Containing Protein|*Ubiquitin|CAV1 protein, human|*Caveolin 1|Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia|Myositis, Inclusion Body|Osteitis Deformans|*Lysosome|ATPase|*Protein Transport|Cell Cycle Proteins|Muscular Dystrophies, Limb-Girdle|*Protein Interaction Motif|Frontotemporal Dementia|Ubiquitination|Endosome|Mutations" 4 ANKRD50 27909246 J. 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Virol. 2016 PMC4859712 10.1128/JVI.00170-16 10 2 0 15 "*Enterovirus|*Secretory Pathway|*Enterovirus Infections|Enterovirus B, Human|Virus Replication|*Protein Transport|Host-Pathogen Interactions|Viral Proteins|Autophagy|Golgi Complex|Cell Line|RNA Silencing|*Cell Movement|*Antigens, Viral" 4 C11orf31 27645994 J. Biol. Chem. 2016 PMC5104929 10.1074/jbc.M116.756155 39 0 0 104 4 C20orf194 27833958 Rom J Morphol Embryol 2016 0 0 0 23 "Humans|*Hepacivirus|*Pharmacogenetics|Ribavirin|IFNL3 protein, human|Antiviral Agents|Interferon-alpha|Hepatitis C, Chronic|inosine triphosphatase|Pyrophosphatases|*Hepatitis C|Interferon alpha-2|Polyethylene Glycols|Genotypes|Interleukins|Sustained Virologic Response|Drug Therapy, Combination|Viral Load|RNA, Viral" 4 C20orf194 27148387 Hepat Mon 2016 PMC4851836 10.5812/hepatmon.35278 1 6 1 23 "Humans|*Ribavirin|*Hepatitis C, Chronic|*Antiviral Agents|Inosine Triphosphatase Deficiency|Pyrophosphatases|Interferon-alpha|Hepatitis C|Genotype|Polymorphism, Single Nucleotide|Hemoglobin|Metabolism, Inborn Errors|Polyethylene Glycols|ITPA protein, human" 4 C2orf80 27271309 Hypertension 2016 PMC5373034 10.1161/HYPERTENSIONAHA.115.06765 0 1 0 2 "Humans|*Blood Pressure|*Sodium|*Molecular Epidemiology|Genome-Wide Association Study|*Sodium Chloride, Dietary|*Blood Pressure Determination|Hypertension|Single Nucleotide Polymorphisms|Chinese|Sodium, Dietary|*Sodium Chloride|Genotype|Genetic Predisposition to Disease|Phenotype|*Epistasis, Genetic|Beijing|Tokyo|MKNK1 protein, human" 4 CCDC171 26840454 Oncotarget 2016 PMC4872719 10.18632/oncotarget.7047 10 21 3 27 "Humans|Female|*Carcinoma, Ovarian Epithelial|*Progression-Free Survival|Genome-Wide Association Study|*Ovarian Cancer|Cystadenocarcinoma, Serous|Fallopian Tube Neoplasms|Adenocarcinoma, Clear Cell|Peritoneal Neoplasms|Carboplatin|Prognosis|Endometrial Neoplasms|Paclitaxel|taxane|Taxoids|Antineoplastic Combined Chemotherapy Protocols|PSIP1 protein, human|*Transcription Factors|Drug Resistance, Neoplasm" 4 CSNK1G3 27485317 BMC Genet. 2016 PMC4969662 10.1186/s12863-016-0421-2 10 6 1 95 "Humans|Cattle|Animals|*Milk Proteins|Genome-Wide Association Study|Denmark|Milk|Caseins|Genotype|*Post-Translational Modifications|Phenotype|Polymorphism, Single Nucleotide|Genome|*Chromosome Structures" 4 DHRS11 26920053 Biochem. 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Monit. 2016 PMC5216666 10.12659/msm.902615 11 1 0 0 "Humans|*RNA, Long Noncoding|*Esophageal Cancer|Prognosis|Gene Expression Regulation, Neoplastic|Kaplan-Meier Estimate|Biomarkers, Tumor|Gene Expression Profiling|Sequencing, RNA|*Whole Exome Sequencing|mRNA|Proportional Hazards Models|Receiver Operating Characteristic|*RNA-Seq" 4 LINC00240 27966444 Oncotarget 2016 PMC5349869 10.18632/oncotarget.13828 35 10 0 0 "*Esophageal Squamous Cell Carcinoma|*RNA, Long Noncoding|*mRNA|*Esophageal Neoplasms|miRNAs|Carcinoma, Squamous Cell|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Computational Biology" 4 LY6G6E 26823690 Clin Epigenetics 2016 PMC4730771 10.1186/s13148-016-0177-6 40 9 1 13 "Humans|*Diabetes Mellitus, Type 2|*Body Mass Index|*Arabs|*Epigenetic|DNA Methylation|Epigenesis, Genetic|CpG Islands|Genome-Wide Association Study|Obesity|Carnitine O-Palmitoyltransferase|Middle East" 4 MIR876 27052555 Sci Rep 2016 PMC4823700 10.1038/srep24149 11 6 1 0 "Humans|Mice|Animals|*Enterovirus Infections|Enterovirus 71, Human|Enterovirus|miRNAs|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling|Upregulation|High-Throughput Nucleotide Sequencing|Host-Pathogen Interactions|Virus Replication|Computational Biology|RNA, Viral|Cell Line|MIRN876 microRNA, human" 4 MTRNR2L2 26769839 J. Physiol. Pharmacol. 2016 4 1 0 101 Humans|*Coronary Artery Disease|*Hyperoxia|*Upregulation|*Pilot Projects|humanin|Coronary Artery Bypass Grafting|*Myocardium|Heart|*Transcriptional Activation|Oxygen 4 OVCH2 26896838 Mol. Reprod. Dev. 2016 10.1002/mrd.22627 3 0 0 4 4 PCAT2 26823525 J. Natl. 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Cell Proteomics 2016 PMC5217785 10.1074/mcp.M116.063313 12 0 0 0 "Humans|*Calcium|*Melanoma|Cachexia|Proteomics|Metabolomics|Biomarkers, Tumor|Muscular Atrophy|*Platelet Activation|Proteins|*Neoplasms, Second Primary|Lipolysis|Oxidation-Reduction" 4 SCGB1C1 27274102 Biol Sport 2016 PMC4885620 10.5604/20831862.1196510 0 1 1 1 Male|Female|Humans|Young Adult|Adult|*Pilot Projects|*Athletes|Secretory Immunoglobulin A|Sports|*Upper Respiratory Tract Infections|Saliva|Common Cold|*Respiratory System Abnormalities|*Nose Diseases|*Biomarkers 4 SLC26A10 27344518 Forensic Sci Int Genet 2016 10.1016/j.fsigen.2016.06.007 3 0 0 3 "Female|*Semen|*Saliva|*DNA Methylation|*Body Fluids|Cervix Mucus|CpG Islands|Forensic Genetics|DNA Fingerprinting|Markers, DNA|*Bodily Secretions|Multiplex Polymerase Chain Reaction|Menstruation" 4 TMEM160 26832135 Obes Surg 2016 PMC4985537 10.1007/s11695-016-2072-9 7 4 1 24 "*Gastric Bypass|*Weight Loss|Genome-Wide Association Study|Obesity, Severe|Body Mass Index|Single Nucleotide Polymorphisms|Waist Hip Ratio|Genotype|*Risk Factors" 4 TMEM38A 27264872 Mol. Cell 2016 PMC4914829 10.1016/j.molcel.2016.04.035 47 12 1 48 "*Muscle Development|Nuclear Envelope|*Membrane Proteins|Myoblasts, Skeletal|Myotube|Cell Differentiation|Nuclear Proteins|Gene Expression Regulation, Developmental|Cell Nucleus|Cell Line|Genes, Developmental" 4 TMSB4Y 27058445 Am. J. Hum. Genet. 2016 PMC4833433 10.1016/j.ajhg.2016.02.023 19 0 1 13 "Humans|Male|Animals|*Neanderthals|*Chromosomes, Human, Y|Hominids|Chimpanzee|Genetic Variation|Genome, Human|Phylogeny|DNA|Exome|Base Sequence|Polymorphism, Single Nucleotide|Spain|KDM5D protein, human|Minor Histocompatibility Antigens|Histone Demethylases" 4 TSPAN11 27502037 Mol. Cell. Endocrinol. 2016 10.1016/j.mce.2016.08.007 10 0 0 33 "Male|Humans|Female|*Kallmann Syndrome|*High-Throughput Nucleotide Sequencing|*Hypogonadism|*Klinefelter Syndrome|FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|DNA Sequencing|Exons|Mutation|Base Sequence|MASTL protein, human|Microtubule-Associated Proteins|Protein-Serine-Threonine Kinases" 4 TSPYL6 27686078 Mol. Neurobiol. 2016 10.1007/s12035-016-0086-x 11 0 0 48 "Humans|*Brain Ischemia|*Stroke|*Asian Continental Ancestry Group|Single Nucleotide Polymorphisms|Haplotypes|Genetic Predisposition to Disease|Alleles|Gene Frequency|Linkage Disequilibrium|Genetic Association Studies|Genotype|Telomere Homeostasis|Odds Ratio|Acid Anhydride Hydrolases|Case-Control Studies|ACYP2 protein, human" 4 TSPYL6 27458158 Oncotarget 2016 PMC5342380 10.18632/oncotarget.10754 5 6 0 48 "Humans|Male|Female|*Polymorphism, Single Nucleotide|*Asian Continental Ancestry Group|Genetic Predisposition to Disease|Gene Frequency|Genotype|Haplotypes|Genetic Association Studies|Alleles|Odds Ratios|Case-Control Studies|Acid Anhydride Hydrolases|Risk Factors" 4 ZCCHC24 27903752 Mol. Cancer Ther. 2016 10.1158/1535-7163.MCT-16-0475 13 0 0 64 "Humans|*Antineoplastic Agents|Nuclear Proteins|Transcription Factors|Cell Line, Tumor|Cell Cycle Proteins|Xenograft Model Antitumor Assays|Proto-Oncogene Proteins c-myc|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Cell Proliferation|Transcription, Genetic|Hematologic Neoplasms|Downregulation|Apoptosis|*Biomarkers|OTX015|Heterocyclic Compounds, 3-Ring|Signal Transduction" 4 ZCCHC24 27050523 Cell Rep 2016 PMC5718363 10.1016/j.celrep.2016.03.025 21 5 1 64 "*Alternative Splicing|*RNA-Binding Proteins|Induced Pluripotent Stem Cells|Cellular Reprogramming|Embryonic Stem Cells|RNA Splicing|Repressor Proteins|Exons|Cell Differentiation|Fibroblasts|Gene Expression Regulation, Developmental|Transcription Factor" 4 ABHD12B 26659575 Cancer Res. 2015 PMC4704135 10.1158/0008-5472.CAN-15-1790 4 0 0 2 "Humans|Male|Adolescent|Young Adult|Adult|Testicular Germ Cell Tumor|*Neoplasms, Germ Cell and Embryonal|*Testicular Neoplasms|Embryonal Carcinomas|Embryonal Carcinoma Cell|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Testis|Cell Line, Tumor|Cell Differentiation" 4 ABHD12B 26482556 Genome Med 2015 PMC4617184 10.1186/s13073-015-0229-0 12 0 1 2 "Swine|Animals|Quantitative Trait Loci|*Obesity|Chromosome Mapping|Genome-Wide Association Study|Adipose Tissue|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Sequencing, RNA|Transcriptome|Gene Expression Profiling|Genomics" 4 ANKRD13A 26038114 Mol. Syst. Biol. 2015 PMC4501846 10.15252/msb.20145880 42 69 8 58 "*Phosphorylation|Proteomics|*Ubiquitylation|Receptors, Antigen, B-Cell|B Cells|Signal Transduction|BCL10 protein, human|B-Cell CLL-Lymphoma 10 Protein|Adaptor Proteins, Signal Transducing|Intracellular Signaling Peptides and Proteins|NF-kappa B|Lymphocyte Activation|Protein Binding" 4 ANKRD50 26509176 J Immunol Res 2015 PMC4609853 10.1155/2015/153132 4 3 1 86 "Humans|*Lupus Nephritis|*Quantitative Trait Loci|Single Nucleotide Polymorphisms|Chinese|Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Genotype|Gene Frequency|Case-Control Studies|PAK7 protein, human|ATG5 protein, human|Autophagy-Related Protein 5" 4 ANKRD50 26509176 J Immunol Res 2015 PMC4609853 10.1155/2015/153132 4 3 1 86 "Humans|*Lupus Nephritis|*Quantitative Trait Loci|Single Nucleotide Polymorphisms|Chinese|Lupus Erythematosus, Systemic|Genetic Predisposition to Disease|Genotype|Gene Frequency|Case-Control Studies|PAK7 protein, human|ATG5 protein, human|Autophagy-Related Protein 5" 4 APOL4 26343748 Am. J. Nephrol. 2015 PMC4589514 10.1159/000439448 7 0 1 22 "Humans|APOL1 protein, human|*Apolipoprotein L1|*African Americans|Apolipoproteins|Lipoproteins, HDL|Molecular Motor Proteins|Myosin Heavy Chains|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Haplotypes|End Stage Kidney Disease|*Disease Progression|Diabetic Nephropathies|Kidney|MYH9 protein, human|APOL4 protein, human|Apolipoproteins L" 4 C9orf142 25941166 Cell Death Differ. 2015 PMC4423191 10.1038/cdd.2015.22 31 11 2 77 4 C9orf142 25574025 Science 2015 PMC4338599 10.1126/science.1261971 89 6 13 77 4 GPR141 25672891 J. Dent. Res. 2015 10.1177/0022034515570315 14 0 2 30 Humans|*Genome-Wide Association Study|Japan|Single Nucleotide Polymorphisms|Genetic Predisposition to Disease|Linkage Disequilibrium|Asian|Gene Frequency|Genotype|Alleles|Genetic Association Studies|Chronic Periodontitis|Case-Control Studies 4 GPR144 26288819 EBioMedicine 2015 PMC4534757 10.1016/j.ebiom.2015.04.003 22 0 5 0 "Humans|China|*Air Pollution|Non-Small-Cell Lung Carcinomas|Lung Cancer|*Mutations|Smoke|Coal|Environmental Exposure|Benzo(a)pyrene|Smoking|Cell Transformation, Neoplastic|Incidence|Case-Control Studies" 4 GPR144 25713288 Pharmacol. Rev. 2015 PMC4394687 10.1124/pr.114.009647 107 0 9 0 "*Pharmacology, Clinical|ADGRE5 protein, human|ADGRG1 protein, human|*G-Protein-Coupled Receptors|Signal Transduction|Cell Membrane|CELSR2 protein, human|Cadherins|CELSR1 cadherin, human|Antigens, CD" 4 HEATR3 25849277 Nat Commun 2015 PMC4396368 10.1038/ncomms7510 18 10 1 57 "ribosomal protein L5, human|Ribosomal Protein|Ribosomes|*Binding Site|RNA, Ribosomal, 5S|*Carrier Proteins|Saccharomyces cerevisiae|*Molecular Chaperones|RNA-Binding Proteins|Protein Binding|*Protein Domains" 4 KIAA1549L 26157485 Mol Cytogenet 2015 PMC4495688 10.1186/s13039-015-0138-3 2 0 0 35 "Child|Humans|*Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|*Precursor Cell Lymphoblastic Leukemia-Lymphoma|PAX5 Transcription Factor|Transcription Factor|Oncogene Proteins, Fusion|Translocation, Genetic|Protein Binding|Mutation|B-Lymphocytes|PAX5 protein, human" 4 KNCN 26197610 Guang Pu Xue Yu Guang Pu Fen Xi 2015 0 0 0 1 "*Cluster Analysis|Algorithms|Pattern Recognition, Automated|Artificial Intelligence|*Research Design|Stars, Celestial|*Health Services|Galaxies" 4 LY6G6E 26276394 J. 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Chem. 2015 PMC4591831 10.1074/jbc.M115.647248 9 0 3 13 4 MIR876 25680557 Gene 2015 10.1016/j.gene.2015.02.018 2 0 0 0 "Humans|Animals|*Haploinsufficiency|Hedgehog Proteins|MicroRNAs|Base Sequence|Gene Expression Profiling|Multigene Family|Bioinformatic|Cell Differentiation|Genomics|Genome|*Craniofacial Abnormalities|MIRN873 microRNA, human|MIRN876 microRNA, human" 4 MIR876 25552301 Brain 2015 PMC4408428 10.1093/brain/awu373 40 0 6 0 "Humans|*Epilepsy, Temporal Lobe|*Sclerosis|*DNA Methylation|*B-DNA|Pilot Projects|Hippocampus|Gene Expression Regulation|RNA, Micro|Neurons|Promoter Regions, Genetic|Epilepsy|Epigenesis, Genetic|Neuronal Plasticity|MIRN876 microRNA, human" 4 NSRP1 26562412 PLoS ONE 2015 PMC4642962 10.1371/journal.pone.0142904 7 0 1 45 "Humans|*Pericardial Fluid|RNA, Micro|Gene Expression Profiling|*Cardiac Surgical Procedures|*Pericardial Effusion|Biomarkers|MIRN423 microRNA, human" 4 NSRP1 26475744 Neuroscience 2015 10.1016/j.neuroscience.2015.10.012 3 5 1 45 "Humans|*Receptor, Cannabinoid|*Schizophrenia|Nerve Tissue Proteins|Cytoskeletal Proteins|Adaptor Proteins, Signal Transducing|Nuclear Proteins|Two-Hybrid System Techniques|Protein Binding|Cannabinoids|DISC1 protein, human|CNR1 protein, human|Receptor, Cannabinoid, CB1" 4 pgam4 26296075 J. Hazard. Mater. 2015 10.1016/j.jhazmat.2015.08.010 9 0 0 93 Humans|Mice|Male|Animals|*Testis|titanium dioxide|Sperm Motility|Glycogen Synthase Kinase 3|*Titanium|Epididymis|Spermatogenesis|Sperm Number|Spermatozoa|*Gene Expression|Nanoparticles 4 pgam4 26242992 Eur. J. Hum. Genet. 2015 PMC4929865 10.1038/ejhg.2015.139 8 0 0 93 "Humans|Male|Child, Preschool|Child|*Genes, X-Linked|*Cerebellar Ataxia|Menkes Disease|ATP7A protein, human|Copper-Transporting ATPases|*Spinocerebellar Ataxias|Anemia, Sideroblastic|Pedigree|Occipital horn syndrome|Ehlers-Danlos Syndrome|Cutis Laxa|Cation Transport Proteins|Genetic Diseases, X-Linked|Adenosine Triphosphatases|Mutation|Exon|Missense Mutation|*Asian Continental Ancestry Group" 4 RNFT1 26403675 Med. Microbiol. Immunol. 2015 10.1007/s00430-015-0432-z 1 0 0 29 "Female|Humans|*Mycobacterium tuberculosis|*Ubiquitin|Tuberculosis|*Endometrium|*Cell Line|cDNA Library|Virulence|Gene Expression|ZFP91 protein, human|Ubiquitin-Protein Ligases" 4 RNU6-1 26352225 Int. J. Mol. Med. 2015 10.3892/ijmm.2015.2338 15 0 4 6 "Humans|*RNA, Micro|Carcinoma, Hepatocellular|Liver Neoplasms|Gene Expression Regulation, Neoplastic|snRNA|Gene Expression Profiling|Liver|Biomarkers, Tumor|Intrahepatic Bile Ducts|Reference Standards|Real-Time Polymerase Chain Reaction" 4 RNU6-1 25943911 J. Gastrointest. Surg. 2015 10.1007/s11605-015-2829-9 35 0 7 6 "Humans|*Circulating MicroRNA|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Barrett Esophagus|MicroRNAs|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|ROC Curve|Real-Time Polymerase Chain Reaction" 4 Rspry1 26497270 Gene 2015 10.1016/j.gene.2015.10.046 1 3 0 48 "Mice|Animals|*Nuclear Protein|*B30.2-SPRY Domain|*Fatty Acids, Nonesterified|MyoD Protein|*Muscle, Skeletal|Myogenin|Myogenic Regulatory Factors|*RING Finger Domains|DNA-Binding Proteins|Promoter Regions, Genetic|Transcription Factors|Enhancer Elements, Genetic|Muscle Atrophy|Binding Sites|Base Sequence|Myogenesis|Cell Line|Transfections" 4 Rspry1 26365341 Am. J. Hum. Genet. 2015 PMC4596891 10.1016/j.ajhg.2015.08.007 7 0 3 48 "Mice|Animals|Pyle disease|Osteochondrodysplasias|Dwarfism|Homozygote|*Mutations|Exome|Musculoskeletal Abnormalities|Phenotype|Pedigree|Mutation, Missense|Intellectual Disability|Whole Exome Sequencing|Genetic Heterogeneity|Amino Acid Sequence" 4 SCGB1C1 26204469 DNA Cell Biol. 2015 PMC4593873 10.1089/dna.2015.2897 0 0 0 1 Humans|*Single Nucleotide Polymorphisms|*Nasal Polyps|Genetic Predisposition to Disease|Alleles|Haplotypes|Genotype|Asthma|Allergy|Case-Control Studies|Nucleotides 4 SLC35F5 26077850 Hum. Genet. 2015 10.1007/s00439-015-1575-0 50 0 3 91 "Child|Humans|*Exome|*Whole Exome Sequencing|Intellectual Disability|Microcephaly|Phenotypes|Developmental Disabilities|DNA Copy Number Variations|Mutation|Sequence Analysis, DNA|Family|Cohort Studies|Qatar" 4 SNORD123 26121239 PLoS ONE 2015 PMC4488298 10.1371/journal.pone.0131287 5 4 1 0 "Male|Female|Animals|Pregnancy|Mice|VDR protein, human|*Receptors, Calcitriol|*Pregnancy Outcome|Mice, Inbred C57BL|*Placenta|CYP24A1|Vitamin D|25-Hydroxyvitamin D3 1-alpha-Hydroxylase|Vitamin D Deficiency|Trophoblasts|Vitamins|Fetal Growth|Fetus|Gene Expression Regulation" 4 TMSB4Y 26702755 Oncotarget 2015 PMC4792601 10.18632/oncotarget.6743 7 7 1 13 "Humans|Male|Female|In Situ Hybridization, Fluorescence|Cell Transformation, Neoplastic|Epithelial Cell|Tumor Suppressor Proteins|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|*Y Chromosome|Genes, Tumor Suppressor" 4 WDR17 26536348 PLoS ONE 2015 PMC4633051 10.1371/journal.pone.0141906 10 1 1 50 "Humans|*Lymphoma, T-Cell, Peripheral|*Mutations|Ataxia-Telangiectasia|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|Cell Cycle Proteins|DNA-Binding Proteins|Nonsense Mutations|*Signal Transduction|ATM protein, human" 4 ZBTB34 26162688 Mol. Cancer Ther. 2015 PMC4618474 10.1158/1535-7163.MCT-15-0148 23 96 3 139 "Humans|Child|*Specificity Protein Transcription Factors|*Reactive Oxygen Species|*Histone Deacetylase Inhibitors|*Rhabdomyosarcoma|Cell Proliferation|Downregulation|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|MicroRNAs|Cell Cycle|Antineoplastic Agents|Colonic Neoplasms|Xenograft Model Antitumor Assays|Repressor Proteins|*Rhabdomyosarcoma, Embryonal" 4 ABHD12B 25056994 J. Dent. Res. 2014 PMC4213253 10.1177/0022034514544506 27 0 3 2 "Adult|Humans|*Chronic Periodontitis|*Genome-Wide Association Study|Single Nucleotide Polymorphisms|Linkage Disequilibrium|Genetic Predisposition to Disease|Genotype|Porphyromonas gingivalis|Phenotype|Genome, Human|Cohort Studies|DAB2IP protein, human|ras GTPase-Activating Proteins|KCNK1 protein, human|Potassium Channels, Tandem Pore Domain" 4 ANKRD50 25278552 J. Cell. Sci. 2014 PMC4231307 10.1242/jcs.156299 32 14 7 86 "Humans|*Endosome|*Intracellular Membranes|Protein Transport|Sorting Nexins|Golgi Apparatus|Vesicular Transport Proteins|Plasma Membrane|CTAG1B protein, human|Biological Transport|Proteomics|HeLa Cells|SNX27 protein, human" 4 ANKRD50 25278552 J. Cell. Sci. 2014 PMC4231307 10.1242/jcs.156299 32 14 7 86 "Humans|*Endosome|*Intracellular Membranes|Protein Transport|Sorting Nexins|Golgi Apparatus|Vesicular Transport Proteins|Plasma Membrane|CTAG1B protein, human|Biological Transport|Proteomics|HeLa Cells|SNX27 protein, human" 4 BPIFB3 25491355 mBio 2014 PMC4324245 10.1128/mBio.02147-14 14 34 2 15 "*Enterovirus B, Human|*Autophagy|Coxsackievirus Infections|Virus Replication|Autophagosome|RNA Interference|RNA, Small Interfering|Host-Pathogen Interactions|RNA, Viral|Endoplasmic Reticulum|RNA, Double-Stranded" 4 DSCC1 24465681 PLoS ONE 2014 PMC3894995 10.1371/journal.pone.0085750 6 18 1 60 "Humans|Animals|Caenorhabditis elegans|Saccharomyces cerevisiae|DNA-Binding Proteins|Transcription Factor DP1|E2F Transcription Factors|E2F1 Transcription Factor|*Tumors, Colorectal|Retinoblastoma-Binding Protein 1|Cell Cycle Proteins|Cell Cycle|Promoter Regions, Genetic|Binding Sites|Cell Division|Apoptosis" 4 GACAT1 25124853 Sci Rep 2014 PMC4133709 10.1038/srep06088 153 10 20 0 "Male|*RNA, Long Noncoding|*Stomach Neoplasms|miRNAs|PTEN protein, human|PTEN Phosphohydrolase|Gene Expression Regulation, Neoplastic|mRNA|Gene Expression Profiling|Cell Transformation, Neoplastic|Cell Line, Tumor|Oncogenesis|Bioinformatic|Head and Neck Squamous Cell Carcinoma|Head and Neck Neoplasms" 4 GACAT1 24833871 World J. Gastroenterol. 2014 PMC4017056 10.3748/wjg.v20.i18.5411 43 0 4 0 "*Stomach Neoplasms|*Non-Coding RNA|Long Non-Coding RNA|MicroRNAs|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|RNA, Small Interfering|Carcinogenesis|Apoptosis" 4 GPR141 24503482 Mol. Phylogenet. Evol. 2014 10.1016/j.ympev.2014.01.022 20 4 3 30 "*Rhodopsin|*Phylogeny|HCAR3 protein, human|G-Protein-Coupled Receptors|Sequence Alignment|Evolution, Molecular|Ligands|neuromedin U 25|Neuropeptides|Signal Transduction|Software|Receptors, Nicotinic" 4 GPR148 24591035 Am. J. Med. Genet. A 2014 10.1002/ajmg.a.36357 1 0 0 89 "Child|Humans|Comparative Genomic Hybridization|Chromosome Deletion|Low-Copy Repeats|Developmental Disabilities|Facies|In Situ Hybridization, Fluorescence|*Disorders, Neurological|Phenotype|*Chromosome Structures|Syndrome|ARHGEF4 protein, human|Rho Guanine Nucleotide Exchange Factors" 4 GPR148 24503482 Mol. Phylogenet. Evol. 2014 10.1016/j.ympev.2014.01.022 20 4 3 89 "*Rhodopsin|*Phylogeny|HCAR3 protein, human|G-Protein-Coupled Receptors|Sequence Alignment|Evolution, Molecular|Ligands|neuromedin U 25|Neuropeptides|Signal Transduction|Software|Receptors, Nicotinic" 4 GRXCR2 24619944 Hum. Mutat. 2014 PMC4123198 10.1002/humu.22545 16 0 3 1 "Humans|Mice|Animals|*Frameshift Mutation|*Hearing Loss|*Deafness|Genes, Recessive|Cochlea|Mutation|Hearing|Pedigree" 4 PRR16 24656129 Mol. Cell 2014 10.1016/j.molcel.2014.02.028 5 5 0 9 "Humans|Mice|Animals|mRNA|Protein Biosynthesis|Mitochondria|*Mammals|Retroviridae|Proteins|Genetic Vectors|Cell Size|Mice, Transgenic|*Cell Growth Processes" 4 RNU6-1 24435880 Neuro-oncology 2014 PMC3956347 10.1093/neuonc/not218 82 0 9 6 "Humans|Adult|*Glioblastoma Multiforme|*Exosomes|*Small Noncoding RNA|Brain Neoplasms|Prognosis|miRNAs|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|Real-Time Polymerase Chain Reaction" 4 TRBV20-1 25173045 Immunol. Lett. 2014 10.1016/j.imlet.2014.08.012 8 0 2 0 "Humans|*Tuberculosis, Pleural|Leukocytes, Mononuclear|Genes, T-Cell Receptor beta|Complementarity Determining Region 3|*Illumina Sequencing|Receptors, Antigen, T-Cell, alpha-beta|Base Sequence|Amino Acid Sequence|Genetic Variation" 4 TSPYL6 24939957 Hum. Reprod. 2014 PMC4093997 10.1093/humrep/deu149 12 7 3 48 "Humans|Female|*Primary Ovarian Insufficiency|*Comparative Genomic Hybridization|*Menopause, Premature|Mutation" 4 TTC27 25493563 PLoS ONE 2014 PMC4262444 10.1371/journal.pone.0114998 2 3 0 42 "Animals|Humans|*Caenorhabditis elegans|*Germ Line|Caenorhabditis elegans Proteins|*Cell Differentiation|*Epidermal Cells|Meiosis|*Epidermis|Stem Cells|Mitosis|Transcription Factors|RNAi|Animals, Genetically Modified|Oocytes" 4 ZBTB34 24732804 Mol. Cell. Biol. 2014 PMC4054319 10.1128/MCB.01602-13 40 6 7 139 "*Reactive Oxygen Species|phenethyl isothiocyanate|*Isothiocyanates|Specificity Protein Transcription Factors|*Anticancer Agents|Downregulation|Apoptosis|Gene Expression Regulation, Neoplastic|Cell Proliferation|MicroRNAs|Cell Line, Tumor|Pancreatic Cancer|Colonic Neoplasms|Xenograft Model Antitumor Assays|Repressor Proteins|RNA Interference|Transcription Factors" 4 ZCCHC24 24860994 Int. J. Dev. Biol. 2014 10.1387/ijdb.130261jb 0 0 0 64 "Animals|*Xenopus laevis|Xenopus Proteins|Gastrula|Embryo, Nonmammalian|Somites|Mesoderm|Gene Expression Regulation, Developmental|Neural Crest|Embryonic Development|Amino Acid Sequence|In Situ Hybridization|Branchial Arches|Cloning, Molecular|Sequence Homology, Amino Acid|Phylogeny" 4 ABHD12B 24077433 J. Alzheimers Dis. 2013 PMC3815519 10.3233/JAD-130989 13 17 2 2 "Genome-Wide Association Study|*Inositol|Alzheimer Disease|Neuroimaging|Cognitive Dysfunction|Magnetic Resonance Imaging|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Brain|Disease Progression|Endophenotypes|Hippocampus|Cohort Studies|*Epistasis, Genetic|Ventricles, Lateral" 4 ANKRD13A 23620728 PLoS ONE 2013 PMC3631221 10.1371/journal.pone.0061099 14 13 3 58 "Animals|*Neural Crest|*Cell Migration|Focal Adhesions|*Lens, Crystalline|Cell Adhesion|Epithelial-Mesenchymal Transition|*Epithelial Cells|Mesoderm|RNA, Micro|Gene Expression Regulation, Developmental|Signal Transduction|Organogenesis|Extracellular Matrix|In Situ Hybridization|Medaka" 4 ANKRD13C 23762421 PLoS ONE 2013 PMC3677937 10.1371/journal.pone.0065767 6 31 0 29 "Humans|MK-0524|HEK293 Cells|Ligands|Signal Transduction|G-Protein-Coupled Receptors|*Receptors, Prostaglandin|*Indoles|Prostaglandin D2|Receptors, Immunologic|Intramolecular Oxidoreductases|Lipocalins|Endoplasmic Reticulum|Plasma Membrane|Molecular Chaperones" 4 ANKRD16 24177593 Cancer Epidemiol. Biomarkers Prev. 2013 PMC3947131 10.1158/1055-9965.EPI-13-0463 14 0 3 1 "Humans|Female|*Bayes Theorem|Receptors, Progesterone|Receptors, Estrogen|Receptor, ErbB-2|White|African Americans|Genetic Predisposition to Disease|Prognosis|Genome-Wide Association Study|Polymorphism, Single Nucleotide|Case-Control Studies" 4 C20orf194 26202029 Hepatol Int 2013 10.1007/s12072-013-9472-x 0 0 0 23 "peginterferon alfa-2a|*Prospective Studies|Republic of Korea|*Interferon-alpha|*Polyethylene Glycols|*Hepacivirus|Chronic Hepatitis C|Ribavirin|Antiviral Agents|Interferon alpha-2|Genotype|Drug Therapy, Combination|RNA, Viral|Sulfonamides" 4 C2orf80 24055526 Eur J Med Genet 2013 10.1016/j.ejmg.2013.09.003 0 0 1 2 "Humans|Mice|Animals|*Array Comparative Genomic Hybridization|*Gonadal Dysgenesis, 46,XY|Gonads|Haploinsufficiency" 4 CCDC86 23828858 EMBO Mol Med 2013 PMC3944460 10.1002/emmm.201202034 28 7 7 95 "Humans|Mice|Animals|*Rituximab|Nuclear Proteins|Transcription Factors|*Antineoplastic Agents|B Cell Lymphoma|Antigens, CD20|Antibodies, Monoclonal, Murine-Derived|*Gene Circuit|Cell Line, Tumor|Xenograft Model Antitumor Assays|Apoptosis|Cell Proliferation|Cell Survival|Gene Expression Regulation, Neoplastic|Immunotherapy" 4 CCDC86 23528659 J. Neuroimmunol. 2013 10.1016/j.jneuroim.2013.02.016 0 0 0 95 Animals|Mice|*Nuclear Protein|*Hippocampus|Neurons|Astrocytes|Dentate Gyrus|*Primates|Stem Cells|Immunohistochemistry|Cell Count|Macaque|Cell Proliferation 4 CCDC86 23439384 Neurochem. Int. 2013 10.1016/j.neuint.2013.02.017 0 0 0 95 Humans|Animals|Mice|*Haloperidol|*mRNA|*Schizophrenia|Antipsychotic Agents|Neurons|Leukocytes 4 CCNI2 23707792 Mol. Cell. Endocrinol. 2013 10.1016/j.mce.2013.05.003 13 0 1 21 "Animals|Humans|*Diabetes Mellitus, Type 2|*Genes, cdc|*Pancreatic Islets|Insulin Secretion|Insulin-Secreting Cells|Insulin|Gene Expression|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|SNPs|Genes, p16|Cyclin-Dependent Kinases|Cyclin|CCNI protein, human|Cyclin I" 4 FAM189A1 23508829 Genes Chromosomes Cancer 2013 10.1002/gcc.22054 8 0 1 2 "Humans|Child|*Haploidy|Homozygote|Sequence Deletion|*Lymphoblastic Leukemia|*Cytogenetic Aberration|*Sequencing, Next-Generation|Karyotyping|Translocation, Genetic|Mutations|Aneuploidy|Genes, p16|Genes, cdc|Risk Assessment|KDM1A protein, human|Histone Demethylases|KDM6B protein, human|Jumonji Domain-Containing Histone Demethylases" 4 HEATR3 23615072 Genes Immun. 2013 PMC3785105 10.1038/gene.2013.19 13 3 0 57 "Humans|*Haplotypes|*Crohn Disease|*Mutation, Missense|*Jews|Genetic Predisposition to Disease|*Carrier Proteins|Nod2 Signaling Adaptor Protein|Gene Frequency|Polymorphism, Single Nucleotide|Alleles|BRD7 protein, human|Chromosomal Proteins, Non-Histone" 4 INSM2 23643663 Genomics 2013 10.1016/j.ygeno.2013.04.016 2 0 0 13 "Humans|*Polyendocrinopathies, Autoimmune|Heterozygote|Mutations|Introns|Transcription Factors|Genotype|Polymorphism, Genetic|Italy" 4 METTL11B 24090352 Biochem. J. 2013 PMC4086624 10.1042/BJ20131163 16 5 0 1 "Humans|Methylation|Methyltransferases|Substrate Specificity|Models, Molecular|NRMT protein, human" 4 PCAT2 23738953 Plant Cell Environ. 2013 10.1111/pce.12144 18 1 3 1 "*Arabidopsis|*Auxin|Arabidopsis Proteins|*Plant Leaves|Gene Expression Regulation, Plant|Plant Growth Regulators|*Mutation|Plants, Genetically Modified|Catalase|Redox|Light|Hydrogen Peroxide|Phenotype|Oxidative Stress" 4 pgam4 23631659 Syst Biol Reprod Med 2013 10.3109/19396368.2013.783887 2 0 0 93 "Male|Humans|Azoospermia, Nonobstructive|*Azoospermia|*Phosphoglycerate Mutase|Single Nucleotide Polymorphisms|Asian Continental Ancestry Group|Infertility, Male|Genetic Predisposition to Disease|Haplotypes|Gene Frequency|Genotype|Mutation|Case-Control Studies|Fertility" 4 PHYHIPL 23629666 Int J Mol Sci 2013 PMC3676784 10.3390/ijms14059305 6 5 0 16 "Animals|Humans|*RNA, Small Interfering|RNA Silencing|MicroRNAs|3' UTR|mRNA|Gene Silencing|*RNA, Double-Stranded" 4 PRR16 24243566 Environ. Mol. Mutagen. 2013 PMC4547934 10.1002/em.21827 42 0 7 9 "Male|Infant|Female|Humans|Pregnancy|*DNA Methylation|*Body Mass Index|*Fetal Blood|*Origin of Life|CpG Islands|Epigenesis, Genetic|Epigenomic|Birth Weight|Prenatal Exposure Delayed Effects|Boston|PLAC1 protein, human|Pregnancy Proteins|ANGPTL2 protein, human|Angiopoietin-like Proteins" 4 PRRC2C 24371231 Cancer Res. 2013 10.1158/0008-5472.CAN-13-1481 26 0 5 151 "*Alternative Splicing|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|SRSF1 protein, human|Serine-Arginine Splicing Factors|*Oncogenes|*Oncogenesis|Exons|Lung Adenocarcinoma|Adenocarcinoma|Gene Expression Regulation, Neoplastic|A549 Cells|Cell Line, Tumor|Gene Expression Profiling|siRNA|RNA, Messenger|Nuclear Proteins|Carcinoma, Squamous Cell" 4 RN7SL1 23932921 Biochim. Biophys. 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Cell 2012 PMC3315809 10.1091/mbc.E11-09-0817 10 34 2 29 "Humans|*Ubiquitin|*Repeat Domain, Ankyrin|HeLa Cells|EGFR protein, human|*Epidermal Growth Factor Receptor|*Endocytosis|Epidermal Growth Factor|*Plasma Membrane|Clathrin|Protein Transport|*Protein Interaction Motif|PSMD10 protein, human|Proteasome Endopeptidase Complex|Phosphorylation|Protein Binding|Ubiquitination" 4 ARMCX2 22249249 Oncogene 2012 10.1038/onc.2011.611 86 0 11 7 "Humans|Female|*Cisplatin|*Ovarian Cancer|*DNA Methylation|Cell Line, Tumor|*B-DNA|*Epigenome|*Carcinoma, Ovarian Epithelial|Azacytidine|Antineoplastic Agents|Drug Resistance, Neoplasm|Decitabine|Gene Expression Regulation, Neoplastic|Promoter Regions, Genetic|MutL Protein Homolog 1|Hydroxamic Acids|Antimetabolites, Antineoplastic|Nuclear Proteins|Xenograft Model Antitumor Assays" 4 C11orf31 22615972 PLoS ONE 2012 PMC3355111 10.1371/journal.pone.0037312 14 25 0 104 4 DGCR6L 22832905 Transl Psychiatry 2012 PMC3337078 10.1038/tp.2012.31 7 2 1 48 "Humans|Child|Adult|*DiGeorge Syndrome|Epigenesis, Genetic|*Psychopathology|Genetic Predisposition to Disease|Chromosome Deletion|Shprintzen Golberg craniosynostosis|Arachnodactyly|Marfan Syndrome|Craniosynostoses|Anxiety Disorders|Chromosome|DGCR6 protein, human|Extracellular Matrix Proteins" 4 DSCC1 23251412 PLoS ONE 2012 PMC3521006 10.1371/journal.pone.0050988 3 4 0 60 "Humans|Child, Preschool|Child|*Gene Knockdown Techniques|*Time-Lapse Imaging|Spindle Apparatus|Mitosis|Cell Cycle|*Cell Differentiation|Neuroblastoma|Cell Proliferation|Apoptosis|Cell Transformation, Neoplastic|Cell Line, Tumor|Gene Expression|UBE2C protein, human|Ubiquitin-Conjugating Enzymes|SNRPD1 protein, human|snRNP Core Proteins" 4 GPR148 22543972 Hum. 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Genet. 2012 PMC3392111 10.1093/hmg/dds166 7 0 1 89 "Child|Humans|Intellectual Disability|Developmental Disabilities|Low-Copy Repeats|Chromosome Aberrations|Chromosome Deletion|Comparative Genomic Hybridization|*Brain|DNA Copy Number Variations|Phenotype|Autism|Epilepsy|Oligonucleotide Array Sequence Analysis|Attention Deficit-Hyperactivity Disorder|*Chromosome Structures|ARHGEF4 protein, human|Rho Guanine Nucleotide Exchange Factors" 4 KHDC1 22731819 DNA Cell Biol. 2012 PMC3429326 10.1089/dna.2012.1682 3 4 0 3 Animals|*Endoplasmic Reticulum|*Apoptosis|mRNA Translation|Caspase 12|RNA-Binding Proteins|Heat-Shock Proteins|Amino Acid Sequence|Signal Transduction|Oocytes 4 pgam4 22590500 PLoS ONE 2012 PMC3348931 10.1371/journal.pone.0035195 5 1 0 93 "Male|Animals|Humans|*Testis|*Polymorphism, Single Nucleotide|Spermatogenesis|*Fertility|Infertility, Male|Spermatozoa|Meiosis|Genes, X-Linked|Fertilization in Vitro" 4 SNORD123 22617881 RNA Biol 2012 PMC3495749 10.4161/rna.19353 23 0 1 0 "Humans|*CpG Islands|*DNA Methylation|*snoRNA|Genes, Tumor Suppressor|Gene Silencing|Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Epigenesis, Genetic|Promoter Regions, Genetic|Non-Coding RNA|Tumorigenesis|Cell Line, Tumor|MicroRNAs" 4 TMEM160 22710927 Int J Obes (Lond) 2012 10.1038/ijo.2012.87 13 0 2 24 "Humans|*Genetic Predisposition to Disease|*Birth Weight|*Chinese|*Obesity|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Body Mass Index|Receptor, Melanocortin, Type 4|Polymorphism, Single Nucleotide|Genome-Wide Association Study|Gene Frequency|Genotype|Alleles|European Continental Ancestry Group|Proteins|Brain-Derived Neurotrophic Factor" 4 TMEM160 22618246 Cell. 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Life Sci. 2012 10.1007/s00018-012-1022-5 20 0 1 24 "Animals|Humans|Genome-Wide Association Study|Drosophila melanogaster|Caenorhabditis elegans|*Obesity|Body Mass Index|Alpha-Ketoglutarate-Dependent Dioxygenase FTO|Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genotype|Transcription Factors|FTO protein, human" 4 TMEM38A 23082221 PLoS ONE 2012 PMC3474742 10.1371/journal.pone.0047829 19 3 1 48 "Humans|Sheep|Animals|*Genome-Wide Association Study|Lentiviruses, Ovine-Caprine|Lentivirus Infection|Sheep Diseases|*Genomics|Breeding|Proviruses|HIV Infections" 4 TRABD2A 22777423 Cell Res. 2012 PMC3515748 10.1038/cr.2012.104 1 0 0 47 "Animals|Xenopus Proteins|Xenopus laevis|Wnt Proteins|Wnt Signaling Pathway|Gastrula|Embryo, Nonmammalian|Embryogenesis|Gene Expression Regulation, Developmental" 4 TRABD2A 22726442 Cell 2012 PMC3383638 10.1016/j.cell.2012.04.039 41 53 2 47 "Humans|Animals|Spemann Organizer|Xenopus laevis|Xenopus Proteins|Body Patterning|Wnt Proteins|Embryo, Nonmammalian|Gene Expression Regulation, Developmental|Membrane Proteins|Embryogenesis|Protein Binding|Signal Transduction|*Oxidation-Reduction" 4 TSPAN11 23068610 FEBS Lett. 2012 10.1016/j.febslet.2012.09.044 5 1 0 33 "Animals|Female|*Drosophila|*Wings, Animal|*Integrins|Drosophila Proteins|Drosophila melanogaster|Cell Polarity|*Epithelial Cell|Actin|Cell Movement|Cell Adhesion|Ovarian Follicle|Ovaries|Oocytes" 4 TTC27 22745009 Ann. Neurol. 2012 PMC3405172 10.1002/ana.23644 29 4 4 42 "Genome-Wide Association Study|Alzheimer Disease|*Hippocampus|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Cognitive Dysfunction|Case-Control Studies|Genotype" 4 TTC27 22696458 Stem Cells 2012 PMC4161212 10.1002/stem.1144 76 0 16 42 Mice|Animals|*Planarians|*Transcriptome|*Pluripotent Stem Cell|RNAi|Cell Differentiation|Adult Stem Cells|Gene Expression Profiling|Regeneration|Cell Proliferation|*Mammals|Homeostasis 4 C20orf194 21683323 Am. J. Hum. Genet. 2011 PMC3135815 10.1016/j.ajhg.2011.05.015 70 2 4 23 "Humans|In Situ Hybridization, Fluorescence|*Ataxia, Spinocerebellar|*Introns|*Motor Neuron|Trinucleotide Repeat Expansion|Genetic Linkage|Pedigree|Lod Score|Haplotype|Phenotype|Amyotrophic Lateral Sclerosis|Base Sequence|Brain|Nuclear Proteins|Mutation, Missense|Mutations" 4 C2orf80 22080834 Hum. Mol. Genet. 2011 10.1093/hmg/ddr532 34 0 3 2 "Humans|Genome-Wide Association Study|*Cell Adhesion|*Psychosis|Schizophrenia|Bipolar Disorder|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Kruppel-Like Transcription Factors|Phenotype|ZNF804A protein, human" 4 INSM2 21343251 Endocrinology 2011 PMC3075939 10.1210/en.2010-1065 0 0 0 13 "Mice|Animals|Humans|*Insulinoma|Basic Helix-Loop-Helix Transcription Factors|Pancreatic Islets|Homeodomain Proteins|Paired Box Transcription Factors|Nerve Tissue Proteins|Pancreas|Cell Differentiation|Gene Expression Regulation, Developmental|Chromatin Immunoprecipitation|Pancreatic Duct|*Pancreas, Exocrine|Pancreatic Neoplasms|INSM1 protein, human|Repressor Proteins|Neurod1 protein, mouse" 4 ISOC2 21898820 Proteomics 2011 10.1002/pmic.201000717 5 1 1 37 "Humans|*Vorinostat|*Histone Deacetylases|Proteomics|Histone Deacetylase Inhibitor|Hydroxamic Acids|Structure-Activity Relationship|Models, Molecular|HepG2 Cell" 4 MIR876 22087292 PLoS ONE 2011 PMC3210160 10.1371/journal.pone.0027325 11 4 0 0 Humans|*Femur Neck|*Genome-Wide Association Study|*Femur|Asian Continental Ancestry Group|European Continental Ancestry Group|Phenotypes|SNPs|Genotype|Bone Density|Body Weight|Body Composition 4 PCDHGA3 21798848 Neuro-oncology 2011 PMC3145471 10.1093/neuonc/nor070 22 0 2 16 "Child|Humans|Aged|*Pinealoma|Neoplasm Recurrence, Local|*PNETs|Medulloblastoma|Cerebellar Neoplasms|Brain Neoplasms|Central Nervous System Neoplasms|DNA Copy Number Variations|Genes, p16|Pineal Gland" 4 PHYHIPL 21878944 J. Cereb. Blood Flow Metab. 2011 PMC3323298 10.1038/jcbfm.2011.120 13 1 2 16 "Animals|Mice|*Mice, Transgenic|*Proteomics|Apolipoprotein E-3|*Apolipoproteins E|Apolipoprotein E4|*Mitochondria|Oxidative Stress|Mitochondrial Proteins|Hippocampus|Genotype|Mass Spectrometry" 4 SCGB1C1 21385388 Respir. Res. 2011 PMC3063214 10.1186/1465-9921-12-28 8 8 1 1 "Humans|*Uteroglobin|*Secretoglobins|*Sinusitis|Nasal Polyps|Rhinitis|*Cytokines|Nasal Mucosa|Epithelial Cells|*Chronic Disease|Cells, Cultured|RNA, Messenger" 4 SLC36A3 21501141 Br. J. Pharmacol. 2011 PMC3246705 10.1111/j.1476-5381.2011.01438.x 33 0 6 50 "Humans|Animals|*Protons|*Transporters, Amino Acid|*Biological Transport|Symporters|Amino Acid Transport Systems, Neutral|Amino Acids|Proline|Xenopus laevis|Tryptophan|Iminoglycinuria|Glycine|*Biochemical Phenomena|Intestine, Small|Tubule, Proximal Renal" 4 ANKRD13C 20959461 J. Biol. Chem. 2010 PMC3003385 10.1074/jbc.M110.142257 9 10 0 29 Humans|*Molecular Chaperone|*G-Protein-Coupled Receptors|Endoplasmic Reticulum|Protein Transport|Cell Membrane|Carrier Proteins|Cytosol|Glycoprotein|HEK293 Cells|Green Fluorescent Proteins|siRNA 4 ARMCX2 20470940 Arch. Med. Res. 2010 10.1016/j.arcmed.2010.03.001 8 3 2 7 "Humans|*Fragile X Syndrome|Cancer|WNT7A protein, human|*Wnt Proteins|*Gene Expression Profiling|FMR1 protein, human|Fragile X Mental Retardation Protein|Oligonucleotide Array Sequence Analysis|Oncogenes|Finland" 4 C11orf31 20723428 Zhonghua Zhong Liu Za Zhi 2010 0 0 0 104 4 CCDC86 19483473 Epigenetics 2009 10.4161/epi.9019 59 0 9 95 "Infant, Newborn|Humans|Female|Pregnancy|*Intrauterine Growth Restriction|Genomic Imprinting|IGF2 protein, human|IGF-2|Placentas|DNA Methylation|PLAGL1 protein, human|Cell Cycle Proteins|Transcription Factors|Tumor Suppressor Proteins|*Infant, Small for Gestational Age|Gene Expression Profiling|Allele|Gene Expression Regulation, Developmental|Gene Expression" 4 DGCR6L 19778628 Int. J. Biochem. Cell Biol. 2009 10.1016/j.biocel.2009.09.008 22 25 2 48 "Animals|Humans|*p21-Activated Kinases|*Stomach Neoplasms|LIMK1 protein, human|*Lim Kinases|Phosphorylation|enhancer-binding protein AP-4|DNA-Binding Proteins|Actin Depolymerizing Factors|Cell Movement|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|F-Actin|Microfilament Proteins|Transcription Factors|Protein Binding|Cell Line, Tumor|Transfection|PAK4 protein, human" 4 gycolysis 19453159 J. Proteome Res. 2009 10.1021/pr900386f 9 0 1 0 "Humans|*Amniotic Fluid|*Proton Magnetic Resonance Spectroscopy|*Metabonomics|*Magnetic Resonance Spectroscopy|Metabolome|*Magnetic Resonance Imaging|Nuclear Magnetic Resonance, Biomolecular|Principal Component Analysis|Amino Acids|Organic Chemicals|Glucose" 4 KHDC1 19129511 Biol. Reprod. 2009 10.1095/biolreprod.108.073684 14 0 4 3 Animals|Phylogeny|*Genetic Evolution|Genomes|Vertebrate|Species Specificity|Genomics|Gene Expression|Reproduction 4 LY6G6E 19807019 Mol. Biol. 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Pharmacokinet. 2009 10.2133/dmpk.24.91 17 0 0 91 "Male|Adult|Female|Pregnancy|Humans|HeLa Cells|*Membrane Transport Proteins|mRNA|Gene Expression|Gene Expression Profiling|PCR|Tissue Distribution|SLC35D1 protein, human|Monosaccharide Transport Proteins|SLC35D2 protein, human|Nucleotide Transport Proteins|SLC35F2 protein, human|Male|Adult|Female|Pregnancy|Humans|HeLa Cells|*Membrane Transport Proteins|mRNA|Gene Expression|Gene Expression Profiling|PCR|Tissue Distribution|SLC35D1 protein, human|Monosaccharide Transport Proteins|SLC35D2 protein, human|Nucleotide Transport Proteins|SLC35F2 protein, human|Male|Adult|Female|Pregnancy|Humans|HeLa Cells|*Membrane Transport Proteins|mRNA|Gene Expression|Gene Expression Profiling|PCR|Tissue Distribution|SLC35D1 protein, human|Monosaccharide Transport Proteins|SLC35D2 protein, human|Nucleotide Transport Proteins|SLC35F2 protein, human" 4 TRBV20-1 19541912 Genome Res. 2009 PMC2765271 10.1101/gr.092924.109 152 0 22 0 "Humans|*Receptors, Antigen, T-Cell, alpha-beta|Genes, T-Cell Receptor beta|Gene Rearrangement, beta-Chain T-Cell Antigen Receptor|*Massively Parallel Sequencing|Complementarity Determining Region 3|Base Sequence|Amino Acid Sequence|T-Lymphocytes|V(D)J Recombination|Genome" 4 WDR17 19727342 Mol. Vis. 2009 PMC2736153 54 1 0 50 "Mice|Animals|*Gene Expression|Oligonucleotide Array Sequence Analysis|Quantitative Trait Loci|Phenotypes|Gene Regulatory Networks|Crosses, Genetic|Gene Expression Profiling|*Eye|Genotype|RNA, Messenger" 4 ACTRT3 18692047 FEBS Lett. 2008 10.1016/j.febslet.2008.07.058 12 1 1 13 "Male|Mice|Animals|*Profilins|*Spermiogenesis|*Cell Nucleus|Spermatid|Testis|Actin|Cytoplasm|Acrosome|Amino Acid Sequence|RNA, Messenger" 4 APOL4 18632255 Schizophr. Res. 2008 PMC3736834 10.1016/j.schres.2008.05.028 11 0 0 22 "Humans|*Haplotypes|APOL1 protein, human|*Apolipoprotein L1|*Polymorphism, Single Nucleotide|*Schizophrenia|European Continental Ancestry Group|Linkage Disequilibrium|Genetic Predisposition to Disease|African Americans|Genotype|Chinese|Lipoproteins, HDL" 4 GPR144 18845549 Mol. Biol. Evol. 2008 10.1093/molbev/msn228 35 0 2 0 prosecretin|*Secretin|Phylogeny|Dictyostelium|*G-Protein-Coupled Receptors|Genetic Evolution|Genome|*Protein Binding|Introns|*Gastrointestinal Hormones|Species Specificity|*Signal Transduction 4 LINGO3 18297755 Gene Expr. Patterns 2008 10.1016/j.modgep.2007.10.003 11 0 1 11 "Animals|Mice|*Embryogenesis|Somites|Embryo, Mammalian|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Amino Acid Sequence|Membrane Proteins|Brain|Ganglia, Dorsal Root|Sequence Homology, Amino Acid|Immunoglobulin|In Situ Hybridization|Mesencephalon|DNA, Complementary" 4 SLC36A3 18802473 PLoS Genet. 2008 PMC2535566 10.1371/journal.pgen.1000195 12 1 0 50 "Horses|Animals|*Mutation, Missense|*Exon|Hair Color|Phenotype|Allele|Chromosome Mapping|Genotype|Dominant Gene|Single Nucleotide Polymorphism|Microsatellite Markers|Amino Acid Sequence|Sequence Analysis, DNA" 4 C10orf76 17959645 Nucleic Acids Res. 2007 PMC2175361 10.1093/nar/gkm847 22 8 5 90 "*HIV-1|*Transcriptional Activation|HIV Long Terminal Repeat|*Promoter Regions, Genetic|RNA, Anti-Sense|siRNA|Gene Expression Regulation, Viral|Reporter Gene|Gene Silencing|Virus Replication|Transcription, Genetic|RNA, Double-Stranded" 4 ISOC2 17658461 Biochem. Biophys. Res. Commun. 2007 10.1016/j.bbrc.2007.06.181 4 4 1 37 "Humans|Female|Mice|Animals|*Cyclin-Dependent Kinase Inhibitor p16|isochorismatase|*Protein A|*Hydrolases|Co-Immunoprecipitation|Cell Line, Tumor|*Cyclin-Dependent Kinase Inhibitor Proteins|Genes, Tumor Suppressor|Yeast Two-Hybrid Assay|Blotting, Western|Cell Transformation, Neoplastic|Cyan Fluorescent Protein|Green Fluorescent Proteins" 4 KHDC1 17913455 Genomics 2007 10.1016/j.ygeno.2007.06.003 30 0 1 3 "Mice|Cats|Dogs|Animals|*Mammals, Eutherian|*Phylogeny|*Oocyte|*Embryo, Mammalian|Amino Acid Sequence|Sequence Alignment|Homeodomain Proteins|Gene Expression Regulation, Developmental|Genomes|Gene Duplication|Multigene Family|RNA, Messenger|Genomics|Ooep protein, mouse|RNA-Binding Proteins" 4 S10A9 17970044 Anticancer Res. 2007 33 0 0 0 "Humans|Mice|Rats|Animals|*Urinary Bladder Neoplasms|*S100 Protein Family|Carcinoma, Transitional Cell|Urothelium|Oligonucleotide Array Sequence Analysis|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Signal Transduction|Calgranulin B|Calgranulin A|S100A5 protein, human|S100A14 protein, human|Calcium-Binding Proteins|S100A16 protein, human|S100a3 protein, mouse" 4 SLC26A10 17693766 Curr. Opin. Nephrol. Hypertens. 2007 10.1097/MNH.0b013e3282e7d7d0 25 6 1 3 "Slc26 Proteins|*Anions|Antiporters|Chloride-Bicarbonate Antiporters|Anion Transport Proteins|Kidney|Oxalates|Chlorides|*Urinary Tract Physiological Phenomena|Channel, Chloride Ion|Sulfates|Cloning, Molecular" 4 SPANXA2 17373721 Prostate 2007 10.1002/pros.20561 13 0 2 1 "Humans|Male|*Prostate Cancer|Genetic Linkage|Chromosome Mapping|*DNA Mutational Analysis|Nuclear Proteins|*Genes, X-Linked|Chromosomes, Human, X|Genetic Predisposition to Disease" 4 TTC27 18056785 Physiol. Genomics 2007 10.1152/physiolgenomics.00147.2007 23 1 0 42 "Mice|Animals|*Hypoxia|SSPN protein, human|*Carrier Proteins|*Glial Cell|*Membrane Proteins|*Cell Death|*Neoplasm Proteins|Hypoxia, Brain|Apoptosis|Neurons|*Gene Expression|Cerebral Cortex|Hippocampus|Downregulation|Oligonucleotide Array Sequence Analysis|Upregulation|Brain|*Lung Diseases" 4 KIAA1210 16489065 Clin. Cancer Res. 2006 10.1158/1078-0432.CCR-05-2072 35 0 0 52 "Humans|Male|*DNA Methylation|*Prostate Cancer|CpG Islands|PDLIM4 protein, human|*DNA-Binding Proteins|DNA Modification Methylases|Promoter Regions, Genetic|*LIM Domain Proteins|Glutathione S-Transferase pi|Gene Expression Regulation, Neoplastic|Decitabine|Azacitidine|Biomarkers, Tumor" 4 LY6G6E 17008713 Protein Sci. 2006 PMC2242401 10.1110/ps.062242606 28 0 3 13 4 SLC35F5 16477629 Int. J. Cancer 2006 10.1002/ijc.21843 21 0 0 91 "Humans|*5 Fluorouracil|Dehydrogenase, Dihydropyrimidine|*Colorectal Cancer|Orotate Phosphoribosyltransferase|*Liver Neoplasms|Thymidylate Synthase|Antimetabolites, Antineoplastic|Thymidine Phosphorylase|*Colon Cancer|*Gene Expression|Hepatic Artery|RNA, Messenger" 4 SPANXA2 17012309 Mol. Hum. Reprod. 2006 10.1093/molehr/gal079 10 0 2 1 "Humans|Male|Mice|Rats|Animals|*Spermatids|*Nuclear Envelope|Spermiogenesis|Acrosome|Spermatozoa|Testis|*Hominidae|Amino Acid Sequence|Nuclear Proteins|Genes, Regulator|X Chromosome|Meiosis|Sequence Alignment|Cell Nucleus|*Morphogenesis|Open Reading Frames|Cytoplasm|SPANXD protein, human" 4 TRBV20-1 16799335 J. Immunother. 2006 PMC1510955 10.1097/01.cji.0000203082.20365.7f 11 0 0 0 "Humans|HLA-DPw4 antigen|Leukocytes, Mononuclear|*HLA-DP beta-Chains|*CD4-Positive T-Lymphocytes|Antigens, Neoplasm|Melanoma|Adoptive Immunotherapy|HLA-A2 Antigen|Epitopes, T-Lymphocyte|Receptors, Antigen, T-Cell, alpha-beta|Histocompatibility Antigens Class II|*Antibodies|Dendritic Cells|Membrane Proteins" 4 ZBTB34 16718364 Mol. Cell. Biochem. 2006 10.1007/s11010-006-9183-x 6 0 0 139 "Animals|Humans|*Transcription Factors|Zinc Finger|Repressor Proteins|Transcription, Genetic|Amino Acid Sequence|PHF20 protein, human|Proto-Oncogene Proteins c-bcl-6|Cell Nucleus|Kruppel-Like Transcription Factors|*Biomarkers, Tumor|Base Sequence|Gene Expression Regulation|Cloning, Molecular|Protein Structure, Tertiary|Sequence Homology, Amino Acid|Protein Binding|DNA, Complementary|RNA, Messenger" 4 ARMCX2 15759267 Dev. Dyn. 2005 10.1002/dvdy.20309 3 0 0 7 "Male|Mice|Animals|*Testis|*Armadillos|*Embryo, Mammalian|*Cell Differentiation|Amino Acid Sequence|In Situ Hybridization|Gene Expression Regulation, Developmental|Sequence Alignment|Transcription, Genetic|Membrane Proteins|Sequence Homology, Amino Acid|RNA, Messenger|Somites|DNA, Complementary|Downregulation" 4 CSNK1G3 16247451 Oncogene 2005 10.1038/sj.onc.1209169 13 6 1 95 "Humans|*RNA Interference|*Proto-Oncogene Proteins c-akt|Signal Transduction|Phosphorylation|Protein Kinase Inhibitors|Phosphatidylinositol 3-Kinases|RNA, Small Interfering|Cell Line, Tumor|inositol polyphosphate multikinase|Phosphotransferases (Alcohol Group Acceptor)|Cell Proliferation|Apoptosis" 4 DGCR6L 15821931 Hum. Genet. 2005 10.1007/s00439-005-1267-2 3 1 0 48 "Humans|Animals|Leukocytes, Mononuclear|Amino Acid Sequence|DiGeorge Syndrome|Base Sequence|Gene Expression|EBV|B Cells|NF-kappa B|Extracellular Matrix Proteins|mRNA|Promoter Regions, Genetic|DGCR6 protein, human" 4 GPR148 15777626 Biochim. Biophys. Acta 2005 10.1016/j.bbagen.2004.12.001 17 1 1 89 "Humans|Rats|Mice|Animals|*Rhodopsin|Phylogeny|GPRC5C protein, human|G-Protein-Coupled Receptors|Evolution, Molecular|*Biological Evolution|TYRP1 protein, human|*Membrane Glycoproteins|Amino Acid Sequence|Expressed Sequence Tags|Fugu|GPR139 protein, human|Nerve Tissue Proteins" 4 gycolysis 16205843 J. Biomed. Sci. 2005 10.1007/s11373-005-9010-5 11 0 1 0 "*Muscle, Smooth, Vascular|PDGF-BB|Myocytes, Smooth Muscle|Proto-Oncogene Proteins c-sis|Cell Proliferation|Cells, Cultured|Signal Transduction|Atherosclerosis|Aorta|Glycolysis" 4 SPANXA2 16251457 Genome Res. 2005 PMC1310635 10.1101/gr.4212705 16 0 1 1 "Humans|Male|Animals|Genetic Linkage|*Prostate Cancer|Prostate|*Gene Cluster|Chromosome Mapping|DNA Mutational Analysis|Chromosomes, Human, X|Segmental Duplications|Nuclear Proteins|Genotype|Genetic Predisposition to Disease|Genes, X-Linked|Neoplasm Proteins|Gene Frequency|*Chromosome Structures|Hominidae" 4 GPR144 15203201 Genomics 2004 10.1016/j.ygeno.2003.12.004 71 0 5 0 "Mice|Humans|Animals|Phylogeny|*G-Protein-Coupled Receptors|Evolution, Molecular|Genome, Human|ESTs|Membrane Proteins|GPR133 protein, human|GPR110 protein, human|Gpr116 protein, mouse|GPR114 protein, mouse" 4 gycolysis 15449018 Plant Cell Rep. 2004 10.1007/s00299-004-0866-z 0 0 0 0 "*Hordeum|*Cotyledon|*Chitinase|*Ascomycota|Gene Expression Regulation, Plant|Genes, Plant|Plant Diseases|Plant Epidermis|Plant Proteins|cDNA|*Gene Expression|Amino Acid Sequence|*Epidermal Cells|*Epidermis" 4 NKX1-1 15183316 Gene Expr. 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Pharmacol. 2019 PMC6965687 10.1111/bph.14793 3 4 0 5 "Humans|*Carcinoma, Non-Small-Cell Lung|*ErbB Receptors|ursolic acid|*Lung Neoplasms|*Mutations|*Protein Kinase Inhibitors|*Triterpenes|*Receptors, Growth Factor|Erlotinib|*Apoptosis|Quinazolines|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|EGFR protein, human" 3 FAM171A1 31649243 Cell Death Dis 2019 PMC6813359 10.1038/s41419-019-2043-x 2 0 0 19 "Humans|*Triple-Negative Breast Cancer|*Prognosis|MIRN92 microRNA, human|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Biomarkers, Tumor|Cell Movement|Transcription Factors|Cell Line, Tumor" 3 FAM171A1 30631046 Oncogenesis 2019 PMC6328622 10.1038/s41389-018-0113-z 1 2 0 19 "Humans|Triple-Negative Breast Cancer|*Receptors, Estrogen|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|MicroRNAs|Cell Movement|Cell Line, Tumor|Cell Proliferation|Estrogen Receptor alpha|Biomarkers, Tumor|Upregulation|Estrogens|MIRN590 microRNA, human" 3 FAM212B 31163079 PLoS Pathog. 2019 PMC6548406 10.1371/journal.ppat.1007817 7 0 0 64 Mice|Animals|*Schistosoma japonicum|*miRNA|Schistosomiasis japonica|*Extracellular Vesicle|*Macrophage 3 FAM45A 31732251 Food Chem 2019 10.1016/j.foodchem.2019.125460 0 0 0 31 "Animals|*Mercury|Tandem Mass Spectrometry|*Fishes|River|Spectrophotometry, Atomic|PAGE, 2D|Water Pollutants, Chemical|Power Plant, Hydroelectric|Liver" 3 FAM45A 30771381 Biochim Biophys Acta Mol Cell Res 2019 10.1016/j.bbamcr.2019.02.006 0 0 0 31 "rab GTPases|Endosomes|*Multivesicular Bodies|Endocytosis|Guanine Nucleotide Exchange Factors|TYRP1 protein, human|*Membrane Glycoproteins|Protein Transport|Intracellular Membrane|Exosomes|EGFR protein, human|Receptor, EGF|*Homeostasis" 3 GLI4 31601895 Sci Rep 2019 PMC6787018 10.1038/s41598-019-51108-w 0 0 0 19 "*Glioblastoma|*Nanofibers|galectin-3, human|*Galectin 3|*Integrins|Brain Neoplasms|Cell Migration|Glioma|Neoplastic Stem Cells|Cell Adhesion|Cell Line, Tumor|Extracellular Matrix|Laminin|Downregulation|Upregulation" 3 GPR89B 31759543 Taiwan J Obstet Gynecol 2019 10.1016/j.tjog.2019.07.031 0 0 0 31 "Pregnancy|Female|Humans|Chromosome 1q21.1 Deletion Syndrome, 1.35-Mb|*Oligohydramnios|*Chromosome Deletion|*Megalencephaly|*Abnormalities, Multiple|*Chromosomes, Human, Pair 1|*Fetus|Amniocentesis|Comparative Genomic Hybridization|Karyotyping|Ultrasonography, Prenatal|Allanson Pantzar McLeod syndrome|*Urogenital Abnormalities|*Mutation|*Kidney Tubules, Proximal" 3 HHLA1 31808064 Genes Genomics 2019 10.1007/s13258-019-00888-6 0 0 0 12 "Animals|Cattle|Iran|*Breeding|Selection, Genetic|Genotype|Quantitative Trait Loci|Phenotypes|Haplotypes|Genomics|Polymorphism, Single Nucleotide" 3 hippo/warts 30799225 Dev. Cell 2019 10.1016/j.devcel.2019.01.007 2 1 0 0 "Animals|Ecdysone|*Autophagy|Drosophila Proteins|Drosophila melanogaster|Drosophila|LATS1 protein, human|Protein-Serine-Threonine Kinases|Signal Transduction|*Cholesterol|RNA, Micro|*Steroids|Nuclear Proteins|Trans-Activators|Gene Expression Regulation, Developmental|ecdysone receptor|Receptors, Steroid|*Cell Movement|Larva" 3 LINC00638 31271316 Biotech Histochem 2019 10.1080/10520295.2019.1622782 1 0 0 0 "Humans|*RNA, Long Noncoding|*circRNA|*Intervertebral Disc Degeneration|MIRN486 microRNA, human|MicroRNAs|mRNA|Gene Ontology|Gene Regulatory Networks|Gene Expression Profiling" 3 MIR501 31875672 Chem. Res. Toxicol. 2019 10.1021/acs.chemrestox.9b00367 0 0 0 0 Humans|*MicroRNAs|mono-(2-ethylhexyl)phthalate|phthalic acid|*Phthalic Acids|Diethylhexyl Phthalate|Plasticizers|*Biological Transport|Cholesterol 3 MIR663B 30896880 Mol Med Rep 2019 10.3892/mmr.2019.10023 1 6 0 1 "Humans|*Urinary Bladder Neoplasms|*Down-Regulation|*Apoptosis|Cell Proliferation|Gene Expression Regulation, Neoplastic|*Genes, Tumor Suppressor|MicroRNAs|Cell Movement|Cell Line, Tumor|*Bladder|Biomarkers, Tumor|Upregulation|Viability, Cell|TUSC2 protein, human|Tumor Suppressor Proteins" 3 MIR663B 30720118 Mol Med Rep 2019 10.3892/mmr.2019.9934 0 2 0 1 "Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Cell Proliferation|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Movement|RNA Interference|Downregulation|Cell Line, Tumor|Upregulation|Apoptosis|Oncogenesis|*Neoplastic Processes|Disease Progression|GAB2 protein, human|Adaptor Proteins, Signal Transducing" 3 PCDHA12 31710242 J. Comput. Biol. 2019 10.1089/cmb.2019.0138 0 0 0 46 "*DNA Methylation|*Transcriptome|*Carcinoma, Squamous Cell|*Carcinoma, Non-Small-Cell Lung|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Lung Neoplasms|Gene Regulatory Networks|MicroRNAs|Gene Expression Profiling" 3 PCNAP1 31410212 Theranostics 2019 PMC6691589 10.7150/thno.34273 9 48 0 0 3 PSMG4 31067643 Int J Mol Sci 2019 PMC6539346 10.3390/ijms20092231 4 1 0 55 "ATP dependent 26S protease|*Proteasome Endopeptidase Complex|*Molecular Chaperones|*Dimerization|Protein Subunits|Models, Molecular|Cytoplasm|Models, Biological|*Biological Phenomena" 3 TRIML1 31633784 Mol. Biol. 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Sci. 2019 0 0 0 0 "*RNA, Long Noncoding|*miRNA|*Colonic Neoplasms|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|RNA, Messenger|Prognosis|Biomarkers, Tumor|Computational Biology|Kaplan-Meier Estimate" 3 WASIR2 31558162 J Transl Med 2019 PMC6764142 10.1186/s12967-019-2068-z 2 0 0 0 "*Methylation|*Lung Adenocarcinoma|*Transcriptome Analysis|RNA, Long Noncoding|Prognosis|Adenocarcinoma|Lung Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|Biomarkers, Tumor|Transcriptome|mRNA|Kaplan-Meier Estimate" 3 ZC3H12B 31299065 Acta Biochim. Pol. 2019 10.18388/abp.2019_2839 0 0 0 63 "*Beauty|Mutagenesis, Insertional|Transposases|DNA Transposable Elements|*Gene Expression|RNase|*Biochemical Phenomena" 3 ZC3H12B 30988100 RNA 2019 PMC6573786 10.1261/rna.071381.119 2 5 0 63 "Humans|RNase|RNA Stability|Interleukin 6|mRNA|3' Untranslated Regions|Transcription Factors|Immunoprecipitation|Inflammation|HeLa Cells|ZC3H12A protein, human" 3 ZNF831 30945665 J. Genet. 2019 1 0 0 10 3 AAED1 30116028 Mol. Psychiatry 2018 10.1038/s41380-018-0210-6 4 0 0 89 "Humans|*Whole Exome Sequencing|*Pedigree|*Attention Deficit Disorder with Hyperactivity|*Genetic Linkage|Exome|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Sequence Analysis, DNA" 3 AAED1 29901208 Oncol. Rep. 2018 10.3892/or.2018.6478 3 3 0 89 "*Stomach Neoplasms|*Glycolysis|Cell Proliferation|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Viability, Cell|Lentivirus|Upregulation|East Asia" 3 ABHD8 30559148 Cancer Res. 2018 PMC6359948 10.1158/0008-5472.CAN-18-2726 4 0 0 5 "Humans|Female|*Carcinoma, Ovarian Epithelial|*DNA Methylation|*Ovarian Neoplasms|Neoplasms, Glandular and Epithelial|CpG Islands|Epigenesis, Genetic|Genome-Wide Association Study|Genetic Predisposition to Disease|Promoter Regions, Genetic|*Genetic Markers|Polymorphism, Single Nucleotide|Case-Control Studies|White Blood Cells" 3 ABRACL 29312627 Oncotarget 2018 PMC5752540 10.18632/oncotarget.22725 3 0 0 27 Humans|Female|*Proteomics|*Endometrial Cancers|Endometrium|Two Dimensional Gel Electrophoresis|Proteome|Mass Spectrometry|Cancer Biomarkers|Uterus|Western Blotting 3 APCDD1L 29568882 Mol Med Rep 2018 PMC5928681 10.3892/mmr.2018.8770 3 18 0 1 "Neoplasm Recurrence, Local|*Prognosis|*Carcinoma, Squamous Cell|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|*Lung Carcinoma, Non-Small-Cell|Biomarkers, Tumor|Lung Neoplasms|Gene Expression Profiling|Gene Regulatory Networks|Kaplan-Meier Estimate|Survival Analysis" 3 ARL14EP 30140741 Sci Adv 2018 PMC6105299 10.1126/sciadv.aat6224 12 1 0 25 "Animals|*Methyltransferase, Histone|*Heterochromatin|Caenorhabditis elegans Proteins|Caenorhabditis elegans|Histone-Lysine N-Methyltransferase|Histones|Methylation|Cell Nucleus|*Chromatin Assembly and Disassembly|Embryo, Nonmammalian|Embryogenesis" 3 CCDC73 29563520 Sci Rep 2018 PMC5862965 10.1038/s41598-018-23176-x 2 0 0 2 3 cep112 30296263 PLoS Biol. 2018 PMC6193740 10.1371/journal.pbio.2004204 4 0 0 6 "Pregnancy|Female|Mice|Animals|*Noncoding RNA|RNA, Anti-Sense|*Genomic Instability|RNA, Long Noncoding|*Oncogene|Transcriptome|RNA Instability|BRCA1 protein, human|BRCA1 Protein|Genomics|Centrosome" 3 CLEC18A 30470801 Sci Rep 2018 PMC6251874 10.1038/s41598-018-35774-w 0 0 0 14 "Humans|*Hepatitis C, Chronic|*Lectin, C-Type|Hepatitis C virus|Cryoglobulinemia|Cryoglobulins|Hepatitis C|Hepatocytes|B-Lymphocytes|Enzyme-Linked Immunosorbent Assay" 3 CLEC18A 30055605 J. 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Res. 2016 10.1161/CIRCRESAHA.116.309398 17 1 0 17 "*Complement C1q|Endothelial Cells|*Cardiac Hypertrophy|Ventricular Remodeling|Myocytes, Cardiac|Heart Failure|Ventricular Dysfunction, Left|TYRP1 protein, human|*Membrane Glycoproteins|Myocardium|Signal Transduction|Fibrosis" 3 C1QTNF9 27576340 BMC Complement Altern Med 2016 PMC5006533 10.1186/s12906-016-1305-8 4 5 1 17 "Mice|Animals|Bees|*Propolis|*Lipid Metabolism|*Glucose|*Periodontitis|Porphyromonas gingivalis|Bacteroidaceae Infections|Inflammation|Mice, Inbred C57BL|Microbiota, Gut|Alveolar Bone Loss|Endotoxemia|Gingiva|Metabolic Diseases|Liver|Disease Models, Animal|Insulin Resistance|Brazil" 3 C9orf92 26857357 Diagn Pathol 2016 PMC4746792 10.1186/s13000-016-0472-8 0 0 1 0 "Humans|Female|*HMGA2 Protein|*Lipoma|Karyotyping|In Situ Hybridization, Fluorescence|Cytogenetic|Cytogenetic Analysis" 3 CDADC1 26945630 Gene 2016 10.1016/j.gene.2016.02.048 2 2 0 53 "*Cytidine Deaminase|Amino Acid Sequence|Base Sequence|Cell Nucleus|Cytoplasm|Sequence Homology, Amino Acid|DNA|RNA|Cytidine" 3 DTHD1 28034876 Carcinogenesis 2016 10.1093/carcin/bgw206 3 0 0 24 "Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*INDEL Mutation|*Polymorphism, Genetic|pre miRNA|Gene Expression Regulation, Neoplastic|Genotype-Phenotype Correlation|Genetic Predisposition to Disease|Allele|Cell Proliferation|Apoptosis|mRNA|Case-Control Studies|XAF1 protein, human|Neoplasm Proteins|Intracellular Signaling Peptides and Proteins" 3 ETV3L 27454520 PLoS ONE 2016 PMC4959717 10.1371/journal.pone.0159779 2 6 1 3 "Humans|*Calcitriol|*Leukocytes, Mononuclear|Genome-Wide Association Study|dihydroxy-vitamin D3|*Vitamin D|Receptors, Calcitriol|Transcription, Genetic|Gene Expression Regulation|Quantitative Trait Loci|Vitamins|Gene Expression Profiling|Cell Proliferation|*Leukocytes|Protein Binding" 3 FAM212B 27748922 Oncol. 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Sci. 2015 PMC4488411 10.1292/jvms.14-0496 0 0 0 0 "Humans|Rats|Mice|Dogs|Animals|Phylogeny|*Macaca fascicularis|Carboxylic Ester Hydrolases|Amino Acid Sequence|Phenacetin|Liver|Microsomes, Liver|Flutamide|cDNA|mRNA|Substrate Specificity|Hydrolysis|AADAC protein, human" 3 ABCC6P1 26029710 Mol Genet Genomic Med 2015 PMC4444165 10.1002/mgg3.137 1 2 0 0 "Humans|*Pseudoxanthoma Elasticum|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|*Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Mutations|Genotype|Gene Frequency|Alleles|Pedigree|Phenotype|Humans|*Pseudoxanthoma Elasticum|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|*Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Mutations|Genotype|Gene Frequency|Alleles|Pedigree|Phenotype" 3 ABCC6P2 26029710 Mol Genet Genomic Med 2015 PMC4444165 10.1002/mgg3.137 1 2 0 0 "Humans|*Pseudoxanthoma Elasticum|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|*Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Mutations|Genotype|Gene Frequency|Alleles|Pedigree|Phenotype|Humans|*Pseudoxanthoma Elasticum|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|*Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Mutations|Genotype|Gene Frequency|Alleles|Pedigree|Phenotype" 3 ABHD17C 26701913 Elife 2015 PMC4755737 10.7554/eLife.11306 53 38 1 31 "Palmitoylation|TYRP1 protein, human|*Membrane Glycoproteins|*Palmitates|Thiolester Hydrolases|Protein Transport|palmostatin B|Propiolactone|Cell Membrane|ras Proteins|Signal Transduction|Postsynaptic Density Protein 95|Protein Processing, Post-Translational|Cysteine|Hydrolases|Cytosol" 3 AKNAD1 26447881 PLoS ONE 2015 PMC4598026 10.1371/journal.pone.0139520 1 32 1 6 "IGF1 protein, human|*Insulin-Like Growth Factor I|*Tumor Necrosis Factor-alpha|*Kinetics|*Cell Differentiation|*Muscle Development|Myoblasts, Skeletal|Muscular Atrophy|*Gene Expression|Cell Line|Apoptosis|Muscle, Skeletal|Cells, Cultured" 3 AKNAD1 26292654 Sci Rep 2015 PMC4543987 10.1038/srep13391 3 6 1 6 "Humans|Mice|Animals|*DNA Copy Number Variations|Genome-Wide Association Study|Jordan|Single Nucleotide Polymorphisms|*Diabetes Mellitus, Type 2|Genetic Predisposition to Disease|Asian Continental Ancestry Group|Case-Control Studies|Genotype|AKNAD1 protein, human|Proteins" 3 ARL9 25818835 Dev. Biol. 2015 PMC4584193 10.1016/j.ydbio.2015.03.010 7 10 0 16 "Animals|Humans|*Xenopus laevis|*Neurogenesis|Neural Stem Cells|Xenopus Proteins|Optic Tectum|Cell Differentiation|Neurons|SOX2 protein, human|SOXB1 Transcription Factors|Cell Proliferation|Tadpoles|Gene Expression Regulation, Developmental|Morpholinos|Electroporation|Gene Knockdown Techniques|FMR1 protein, human|Fragile X Mental Retardation Protein" 3 ARL9 25701811 Environ. Res. 2015 PMC4385453 10.1016/j.envres.2015.02.004 13 3 1 16 "Humans|Male|Infant|Female|Pregnancy|*Cadmium|*DNA Methylation|*Placenta|Maternal Exposure|Fetal Growth|Birth Weight|Environmental Pollutants|Epigenesis, Genetic|Fetal Growth Retardation" 3 CARMIL3 26578515 J. Biol. 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Chem. 2015 PMC4571857 10.1074/jbc.M115.649814 5 2 0 8 "Humans|*Lectins, C-Type|*Gene Cluster|Sequences, Amino Acid|fucoidan|Polysaccharides|Binding Sites|*Specificity" 3 CORO7 25887538 BMC Neurosci 2015 PMC4364644 10.1186/s12868-015-0151-9 2 1 0 101 "Animals|Mice|Humans|*Flies|Genome-Wide Association Study|coronin|*Body Weight|Obesity|Eating|Mice, Inbred C57BL|Adipose Tissue|Energy Metabolism|RNA, Messenger" 3 EDDM3A 26662397 Genet. Mol. Res. 2015 10.4238/2015.December.7.17 7 0 0 0 "Humans|Male|*Azoospermia|*DNA Copy Number Variations|Male sterility due to Y-chromosome deletions|Infertility, Male|Sex Chromosome Disorders of Sex Development|Sex Chromosome Aberrations|*Chromosomal Abnormalities|Oligozoospermia|Chromosomes, Human, Y|Chromosome Deletion|Spermatogenesis|Chromosomes, Human, X|Mutation|Genetic Testing|Phenotype|NPHP1 protein, human|Membrane Proteins|Adaptor Proteins, Signal Transducing" 3 EXD1 26669262 Mol. 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Online 2014 10.1016/j.rbmo.2014.04.017 3 0 0 2 3 DEFB122 25397683 PLoS ONE 2014 PMC4232509 10.1371/journal.pone.0112786 20 10 4 0 "*Primary Myelofibrosis|NFE2L2 protein, human|*NF-E2-Related Factor 2|*Down-Regulation|Thrombocythemia, Essential|Polycythemia Vera|Myeloproliferative Disorders|*Disease Progression|*Genomic Instability|*Antioxidants|*GA-Binding Protein Transcription Factor|*Neoplasms|Oxidative Stress|Bone Marrow Neoplasms|Reactive Oxygen Species|Signal Transduction|Inflammation|Upregulation" 3 DTHD1 24911043 Ophthalmic Genet. 2014 10.3109/13816810.2014.924017 2 0 0 24 "Humans|Female|Saudi Arabia|CYP1B1 protein, human|*Cytochrome P-450 CYP1B1|*Hydrophthalmos|Pedigree|Mutations|Eye Proteins|*Karyotyping|*Optic Nerve Diseases" 3 EDDM3A 24501866 Akush Ginekol (Sofiia) 2014 2 0 0 0 "Humans|Male|*Oligoasthenoteratozoospermia|*Azoospermia|*Asthenozoospermia|*Infertility, Male|Chromosome 14q, partial deletions|Chromosome Deletion|Chromosomes, Human, Y|Comparative Genome Hybridization|Spermatogenesis|Spermatozoa|*Genomics|Chromosomes, Human, Pair 14|SPAG11B protein, human|Antigens, Surface" 3 EFCAB13 25335771 Int. J. Cancer 2014 PMC4355047 10.1002/ijc.29276 3 14 0 4 "Humans|Male|*Genetic Predisposition to Disease|Prostate cancer, familial|*Prostate Cancer|Single Nucleotide Polymorphisms|Prostate|Chromosome Mapping|Genetic Linkage|Quantitative Trait Loci|Genotype|HOXB13 protein, human|Homeodomain Proteins|Alleles|Genetic Variation|*Chromosome Structures|Sequencing, RNA|Finland" 3 FAM91A1 25198678 J. Proteome Res. 2014 PMC4227559 10.1021/pr500656z 7 7 1 63 "Animals|Mice|*Dysbindin|*Synaptosomes|*Proteome|Dystrophin-Associated Proteins|Synapses|Carrier Proteins|Nerve Tissue Proteins|Lectins|Isoforms|Schizophrenia|Neuroplasticity|Mice, Transgenic|Brain|Dtnbp1 protein, mouse" 3 FBXO18 24470074 Cancer Epidemiol. Biomarkers Prev. 2014 PMC3976694 10.1158/1055-9965.EPI-13-1043 10 5 1 154 "*Genome-Wide Association Study|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|*Risk|Genetic Loci|Genotype|Case-Control Studies|Odds Ratio" 3 GLI4 25211466 J. Med. Chem. 2014 10.1021/jm500522y 2 0 0 19 "C-glycoside|*Glioma|Glioblastoma|*Glycosides|Brain Neoplasms|Drug Screening Assays, Antitumor|*Cardiac Glycosides|Cell Line, Tumor|Antineoplastic Agents|Xenograft Model Antitumor Assays|Cell Proliferation|Cell Movement|Astrocyte|*Neoplastic Processes" 3 METAP1D 24602487 Mol Autism 2014 PMC3946266 10.1186/2040-2392-5-21 9 1 0 9 "Animals|Mice|STS protein, human|Steroid Sulphatase|*Brain|*Gene Expression Regulation|*Disease Models, Animal|*Disorder, Neurodevelopmental|O-Methyltransferase, Acetylserotonin|Autism|Phenotypes|Corpus Striatum" 3 MIR501 25426415 FEBS Open Bio 2014 PMC4241533 10.1016/j.fob.2014.10.016 0 37 1 0 "Humans|Adult|*Carcinoma, Renal Cell|Kidney Cancer|MicroRNAs|Downregulation|MTOR protein, human|TOR Serine-Threonine Kinases|Cell Proliferation|Gene Expression Regulation, Neoplastic|Apoptosis|Prognosis|Tumor Suppressor Protein p53|Upregulation|Cell Line, Tumor|Ubiquitination" 3 MIR502 24677135 Oncol. Rep. 2014 10.3892/or.2014.3105 11 5 1 0 "Humans|*Down-Regulation|*TNF Receptor-Associated Factor 2|MCF-7 Cells|3' Untranslated Region|MicroRNAs|Gene Expression Regulation, Neoplastic|Cell Proliferation|Apoptosis|Genes, Tumor Suppressor|Cell Line, Tumor|Cell Movement|RNA, Messenger|Oncogenesis|MIRN502 microRNA, human" 3 PCDHA13 25418975 Cancer Med 2014 PMC4312117 10.1002/cam4.335 0 1 1 15 "Humans|Female|*Uterine Cervical Neoplasms|*Human Papilloma Virus|*Papillomavirus Infections|Cervical Intraepithelial Neoplasia|Cervix|*Cadherins|Early Detection of Cancer|DNA, Viral|Carcinoma, Squamous Cell|DNA Methylation|Biomarkers, Tumor|Specificity|PCDHA4 protein, human|Neuropeptides|Receptors, Cell Surface|Cell Adhesion Molecules, Neuronal" 3 PHF21B 25454821 Mol Oncol 2014 PMC5528662 10.1016/j.molonc.2014.09.009 5 0 0 48 "Humans|*Squamous Cell Carcinoma of Head and Neck|CpG Island|DNA Methylation|Head and Neck Neoplasms|Promoter Regions, Genetic|Carcinoma, Squamous Cell|Epigenesis, Genetic|DNA methyltransferase 3B|DNA (Cytosine-5-)-Methyltransferases|DNA, Neoplasm|Gene Expression Regulation, Neoplastic|Tumor Suppressor Proteins|Cell Line, Tumor|Genes, Tumor Suppressor" 3 TCTEX1D4 24606217 OMICS 2014 PMC3976573 10.1089/omi.2013.0133 1 0 0 14 "Humans|Male|*Dyneins|*Testis|Sperm Motility|*Spermatozoa|Cytoplasmic Dyneins|Amino Acid Sequence|Yeast Two-Hybrid Assay|Sequence Homology, Amino Acid|Proteins|TCTEX1D2 protein, human" 3 C9orf92 24090760 J. Neurol. Sci. 2013 10.1016/j.jns.2013.09.013 7 0 0 0 "Humans|*Frontotemporal Dementia|*C9orf72 Protein|*Pick Disease of the Brain|DNA Repeat Expansion|Amyotrophic Lateral Sclerosis|*Mutations|DNA-Binding Proteins|*Phenotypes|Neuropathology|Inclusion Bodies|Brain|Cohort Studies|C9orf72 protein, human" 3 CCDC177 24357125 Am. J. Med. Genet. A 2013 10.1002/ajmg.a.36321 0 0 1 2 "Male|Humans|*Intellectual Disability|*Brachydactyly|Chromosome Deletion|*Congenital Heart Defects|Comparative Genomic Hybridization|Abnormalities, Multiple|Truncus Arteriosus|Phenotype|Genetic Association Studies|Haploinsufficiency|Chromosome Banding|*Chromosome Structures|SMOC1 protein, human|Osteonectin|Slc39a9 protein, human|Cation Transport Proteins|KIAA0247 protein, human" 3 ETV3L 23824578 Development 2013 10.1242/dev.093716 9 7 1 3 "Animals|*Retinoic Acid|*Neurogenesis|*Transcription Factors|ERF protein, human|*Repressor Proteins|Xenopus laevis|Cell Differentiation|Xenopus Proteins|Signal Transduction|Gene Expression Regulation, Developmental|Neurons|Nervous System" 3 FRA10AC1 23900196 Gene 2013 10.1016/j.gene.2013.07.039 1 1 0 42 "*Microalgae|*Computational Biology|Sequence Alignment|Amino Acid Sequence|Protein Conformation|Sequence Homology, Amino Acid|Sequence Analysis, DNA|Proteins|Phylogeny|Models, Molecular|Plants" 3 KANSL1L 23558233 Neurotoxicology 2013 PMC4615717 10.1016/j.neuro.2013.03.010 12 3 0 36 "Male|Mice|Animals|*1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine|*MPTP Poisoning|DOPAC|Dopamine|Tyrosine Hydroxylase|Corpus Striatum|Homovanillic Acid|Substantia Nigra|Dopamine Plasma Membrane Transport Proteins|Serotonin|Neostriatum|Mice, Inbred C57BL|Glial Fibrillary Acidic Protein|Parkinson Disease|Neuroprotective Agents|Neurons|Genetic Variation|*Systems Analysis" 3 LRRC23 23449886 Sleep 2013 PMC3571755 10.5665/sleep.2466 20 0 2 2 "*ARNTL Transcription Factors|*Sleep|CLOCK Proteins|Period Circadian Proteins|*Phenotype|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Circadian Rhythm|Genotype|Nerve Tissue Proteins|*Chromosome Structures" 3 MIR637 23610052 Am. J. Med. Genet. A 2013 10.1002/ajmg.a.35923 5 0 0 0 "Child|Humans|Cell Line, Tumor|DNA-Binding Proteins|Transcription Factors|Intellectual Disability|Chromosome Deletion|Macrocephaly|Abnormalities, Multiple|Developmental Disabilities|Microcephaly|Phenotype|*Chromosome Structures|In Situ Hybridization, Fluorescence|ZBTB7A protein, human|DAPK3 protein, human|Death-Associated Protein Kinases|MIRN637 microRNA, human|MicroRNAs" 3 TCTEX1D4 24130861 PLoS ONE 2013 PMC3795061 10.1371/journal.pone.0077236 1 2 0 14 Male|Animals|*Pikas|*Protein Phosphatase 1|*Testis|Amino Acid Sequence|Mammals|Phylogeny|*Cytoskeletal Proteins|*Phosphoproteins 3 TCTEX1D4 23789093 Biol Open 2013 PMC3654263 10.1242/bio.20131065 4 19 0 14 Humans|Male|*Testis|*Protein Phosphatase 1|Sperm Motility|Spermatogenesis|Spermatozoa|Dynein|*Cytoskeletal Proteins|*Microtubule|Isoforms|Phosphorylation|Signal Transduction|*Phosphoproteins|Acrosome|*Biochemical Phenomena 3 TTC9B 23689534 Mol. Psychiatry 2013 PMC7039252 10.1038/mp.2013.62 42 0 4 5 "Humans|Female|Pregnancy|Mice|Animals|*Depression, Postpartum|*DNA Methylation|Prospective Studies|*Genetic Markers|Epigenesis, Genetic|Oestradiol|Postpartum|Receiver Operating Characteristic|Estrogens|HP1BP3 protein, mouse|Nuclear Proteins" 3 ZBTB21 23783273 Genome Res. 2013 PMC3759718 10.1101/gr.147991.112 20 0 4 163 Humans|*Down Syndrome|*Congenital Heart Defects|*DNA Copy Number Variations|Trisomy|Genotype|Chromosome 21|Case-Control Studies 3 ABCC6P1 22873774 BMC Res Notes 2012 PMC3434077 10.1186/1756-0500-5-425 3 1 0 0 "Humans|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Pseudoxanthoma Elasticum|Genetic Variation|Polymorphism, Genetic|Mutation|European Continental Ancestry Group|Humans|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Pseudoxanthoma Elasticum|Genetic Variation|Polymorphism, Genetic|Mutation|European Continental Ancestry Group" 3 ABCC6P2 22873774 BMC Res Notes 2012 PMC3434077 10.1186/1756-0500-5-425 3 1 0 0 "Humans|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Pseudoxanthoma Elasticum|Genetic Variation|Polymorphism, Genetic|Mutation|European Continental Ancestry Group|Humans|*Pseudogenes|*DNA Copy Number Variations|ABCC6 protein, human|Multidrug Resistance-Associated Proteins|*ATP-Binding Cassette Transporters|Pseudoxanthoma Elasticum|Genetic Variation|Polymorphism, Genetic|Mutation|European Continental Ancestry Group" 3 CCDC108 22761584 PLoS Genet. 2012 PMC3386170 10.1371/journal.pgen.1002775 36 9 7 31 Humans|Male|Animals|*Chickens|*Sperm Motility|*Comb|*Mutation|Phenotype|Alleles|Homozygote|Spermatozoa|SOXD Transcription Factors|Testis|Embryonic Development 3 CT45A2 22846743 Mol Oncol 2012 PMC5528393 10.1016/j.molonc.2012.06.004 0 0 1 5 "Adult|Child|Humans|In Situ Hybridization, Fluorescence|Myeloid-Lymphoid Leukemia Protein|*Leukemia, Myeloid, Acute|Translocation, Genetic|Oncogene Proteins, Fusion|Histone-Lysine N-Methyltransferase|Acute Lymphoblastic Leukemia|*Acute Disease|Cytogenetic|Gene Rearrangement|MLLT11 protein, human|Neoplasm Proteins|Proto-Oncogene Proteins|MLL-MLLT3 fusion protein, human" 3 DTHD1 23105016 Genome Res. 2012 PMC3561865 10.1101/gr.144105.112 76 0 9 24 "Humans|*Exome|*Retinal Dystrophy|*Whole Exome Sequencing|*Mutations|DNA Mutational Analysis|Pedigree|Genetic Association Studies|Phenotype|Genotype|Genomics|Cohort Studies|C21orf2 protein, human" 3 MIR219-1 22661538 Clin. Cancer Res. 2012 PMC4141857 10.1158/1078-0432.CCR-11-2951 29 5 4 1 "Humans|*Colorectal Cancer|*Adenocarcinoma|Single Nucleotide Polymorphisms|Prognosis|Neoplasm Staging|Biomarkers, Tumor|MicroRNAs|Neoplasm Recurrence, Local|Genotype" 3 PCDHAC1 22610075 Carcinogenesis 2012 PMC3418891 10.1093/carcin/bgs177 52 0 4 25 "Humans|*Carcinoma, Renal Cell|*CpG Islands|*Epigenome|Kidney Neoplasms|DNA Methylation|*Phenotype|Prognosis|Gene Expression Regulation, Neoplastic|Carcinogenesis|Kidney|Kidney Cortex|SLC13A5 protein, human|Symporters" 3 PCNAP1 22309575 BMC Res Notes 2012 PMC3296674 10.1186/1756-0500-5-87 2 0 0 0 "Humans|PCNA protein, human|*Proliferating Cell Nuclear Antigen|*Pseudogenes|*Genome, Human|*Genes, cdc|DNA Replication|DNA Repair|Cloning, Molecular" 3 SLC7A6OS 22242013 PLoS Genet. 2012 PMC3252277 10.1371/journal.pgen.1002425 32 24 3 44 Humans|Mice|Animals|*Fibrillin-1|Fibrillin|Microfibril|Marfan Syndrome|Weill-Marchesani Syndrome|Extracellular Matrix|Microfilament Proteins|Dwarfism|Transforming Growth Factor beta|Mutation|Signal Transduction|Metalloendopeptidases 3 TP53TG3 22828807 Eur. 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Chem. 2011 PMC3307324 10.1074/jbc.M111.305334 6 4 1 12 "Animals|Female|Humans|*Epitopes|HEK293 Cells|*Carcinoma, Ovarian Epithelial|*Ovarian Cancer|*Oligosaccharides|*Antibodies, Monoclonal, Humanized|Antibodies, Monoclonal|Galactose|Glycosyltransferases|Biomarkers, Tumor|Sulfotransferases|B3GNT7 protein, human|N-Acetylglucosaminyltransferases" 3 GDPGP1 21507950 J. Biol. Chem. 2011 PMC3122210 10.1074/jbc.M111.238774 14 0 1 50 "Humans|Animals|Mice|*Caenorhabditis elegans|*Glucose|*Nucleoside Diphosphate Sugars|*Sugar|HEK293 Cells|*Phosphorylases|Arabidopsis Proteins|Arabidopsis|Guanosine Diphosphate Sugars|*Glycogen Phosphorylase, Muscle Form|glucose-1-phosphate|Glucosephosphates|Guanosine Diphosphate Mannose|*Mammals|Vitamin C|Substrate Specificity|Sequence Homology, Amino Acid|Kinetics" 3 MIR637 21809363 Hepatology 2011 10.1002/hep.24595 52 9 4 0 "Mice|Animals|*Carcinoma, Hepatocellular|STAT3 protein, human|*STAT3 Transcription Factor|*Liver Neoplasms|Mice, Nude|*Tumorigenesis|miRNA|*Cell Transformation, Neoplastic|Cell Proliferation|Apoptosis|Downregulation|Hep G2 Cells|Genes, Tumor Suppressor|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Signal Transduction|*Primate|Phosphorylation" 3 PCDHA13 21962230 Mol. Cancer 2011 PMC3193026 10.1186/1476-4598-10-124 0 9 5 15 "Humans|*DNA Methylation|*Glioma|Promoter Regions, Genetic|Brain Neoplasms|CpG Islands|DNA (Cytosine-5-)-Methyltransferases|Gene Expression Regulation, Neoplastic|MicroRNAs|Cell Line, Tumor|MIRN185 microRNA, human" 3 PSMG4 21249144 PLoS ONE 2011 PMC3020958 10.1371/journal.pone.0016171 38 25 3 55 "Mice|Animals|*Mice, Knockout|*B-Cell Lymphoma 3 Protein|Nuclear Factor-Kappab|Muscular Atrophy|*Atrophy, Disuse|TRIM63 protein, human|Tripartite Motif Proteins|Muscle Proteins|NF-kappa B p50 Subunit|Chromatin Immunoprecipitation|Proto-Oncogene Proteins|Genes, Reporter|Promoter Regions, Genetic|Signal Transduction|Ubiquitin-Protein Ligases|Protein Binding|Muscle, Skeletal|FBXO9 protein, mouse" 3 ANKMY2 21124868 PLoS Genet. 2010 PMC2991253 10.1371/journal.pgen.1001199 10 8 0 48 "Animals|Mice|*Cilia|Caenorhabditis elegans|*Guanylyl Cyclase|*MYND Domains|Caenorhabditis elegans Proteins|Protein Transport|Mutations|Phenotype|Alleles|Signal Transduction|Genes, Regulator|Cyclic GMP|Trpv4 protein, mouse|TRPV Cation Channels|Ift122 protein, mouse|Intracellular Signaling Peptides and Proteins|OSM-9 protein, C elegans|Nerve Tissue Proteins" 3 C19orf24 20623358 Hum. Genet. 2010 10.1007/s00439-010-0859-7 11 0 1 14 "Humans|Syndrome, Peutz-Jegher's|Mutations, Germline|STK11 protein, human|Protein-Serine-Threonine Kinases|Exons|Point Mutation|Phenotype|Gene Deletion|*Complement Factor B|DNA Sequencing|ATP5D protein, human" 3 C1QTNF9 21159786 Am. J. Clin. Nutr. 2010 PMC3021435 10.3945/ajcn.110.002949 21 1 0 17 Humans|*Double-Blind Method|*Cross-Over Studies|*Magnesium|*Proteomics|*Biomarkers|Dietary Supplements|C-Reactive Protein|Blood Glucose|Insulin|*Gene Expression Profiling|Oxidative Stress|*Genomics|Overweight 3 CT45A2 20920256 BMC Cancer 2010 PMC2956734 10.1186/1471-2407-10-518 0 0 1 5 "Humans|Child|*Leukemia, Biphenotypic, Acute|Myeloid-Lymphoid Leukemia Protein|Oncogene Proteins, Fusion|Translocation, Genetic|Leukemia, Myeloid, Acute|*RNA Splicing|Histone-Lysine N-Methyltransferase|Chromosome Banding|Chromosome Breakage|Base Sequence|In Situ Hybridization, Fluorescence|Amino Acid Sequence" 3 LLPH 20399259 Gene 2010 10.1016/j.gene.2010.03.016 0 0 0 71 "*Streptomyces|Streptomyces tendae|Streptomyces albus|*Gene Cluster|Gene Expression Regulation, Bacterial|Base Sequence|Genes, Bacterial|Antibiotic|Bacterial Proteins|Methyltransferases" 3 MIR502 20818337 Mod. Pathol. 2010 10.1038/modpathol.2010.177 25 0 4 0 "Humans|Female|progesterone receptor B|Progesterone Receptor|ERBB2 protein, human|Receptor, ErbB-2|Receptors, Estrogen|KRT5 protein, human|Cytokeratin 5|Keratin-6|Immunohistochemistry|Biomarkers, Tumor|Prognosis|Lymph Nodes|MicroRNAs|Biological Products|MIRN362 microRNA, human" 3 TP53TG3 20736252 Hum. Mol. Genet. 2010 PMC2957319 10.1093/hmg/ddq356 12 0 0 2 "Humans|DNA Copy Number Variations|Epistasis, Genetic|Genotype|Phenotype|Quantitative Trait Loci|Gene Expression" 3 TRIML1 20187927 Cerebrospinal Fluid Res 2010 PMC2841093 10.1186/1743-8454-7-6 8 0 0 4 *Arachnoid Cysts|*DNA Copy Number Variations|*Gene Expression Profiling|*Microarray Analysis|Headache|Dizzyness|*Head|*Musculoskeletal System|DNA 3 PCDHA12 19797050 J. Biol. Chem. 2009 PMC2797272 10.1074/jbc.M109.046938 20 0 0 46 "Mice|Animals|*Regulatory Gene|Exons|Purkinje Cells|Multigene Family|Neurons|Gene Expression|Alleles|Axons|Promoter Regions, Genetic|Models, Genetic|Cadherins|Gene Expression Profiling|RNA, Messenger" 3 PCDHAC1 19797050 J. Biol. Chem. 2009 PMC2797272 10.1074/jbc.M109.046938 20 0 0 25 "Mice|Animals|*Regulatory Gene|Exons|Purkinje Cells|Multigene Family|Neurons|Gene Expression|Alleles|Axons|Promoter Regions, Genetic|Models, Genetic|Cadherins|Gene Expression Profiling|RNA, Messenger" 3 TRIML1 19156909 Mol. Reprod. Dev. 2009 10.1002/mrd.20997 3 0 0 4 "Humans|Infant, Newborn|Mice|Animals|RBX1 protein, human|*Carrier Proteins|*Embryo Implantation|Zinc Finger|Blastocyst|Yeast Two-Hybrid Assay|Proteins|Ubiquitin|Amino Acid Sequence|Embryo Transfer|Embryo, Mammalian|Gene Expression Regulation, Developmental|Embryogenesis|Cell Line" 3 zfyve28 19460345 Dev. Cell 2009 PMC3356849 10.1016/j.devcel.2009.03.015 11 22 1 29 "Humans|Endosomes|*Signal Transduction|Phosphoproteins|Endosomal Sorting Complexes Required for Transport|Protein Transport|EGFR protein, human|Epidermal Growth Factor Receptor|*Biological Transport|Endocytosis|Ubiquitin|Ubiquitination|Lysosomes|Protein Binding|Carrier Proteins|Down-Regulation" 3 ABCC6P1 18405356 BMC Genomics 2008 PMC2329642 10.1186/1471-2164-9-165 24 2 0 0 "Male|Humans|*Pseudogenes|*ATP-Binding Cassette Transporters|Genome, Human|Sequence Analysis, DNA|Transcription, Genetic|Male|Humans|*Pseudogenes|*ATP-Binding Cassette Transporters|Genome, Human|Sequence Analysis, DNA|Transcription, Genetic" 3 ABCC6P2 18405356 BMC Genomics 2008 PMC2329642 10.1186/1471-2164-9-165 24 2 0 0 "Male|Humans|*Pseudogenes|*ATP-Binding Cassette Transporters|Genome, Human|Sequence Analysis, DNA|Transcription, Genetic|Male|Humans|*Pseudogenes|*ATP-Binding Cassette Transporters|Genome, Human|Sequence Analysis, DNA|Transcription, Genetic" 3 GAL3ST3 18716796 Parasitol. Res. 2008 10.1007/s00436-008-1152-8 12 0 1 12 "Rats|Animals|*Nippostrongylus|*Sulfotransferases|sulfomucin|*Mucin|Sialomucin|*Intestinal Epithelium|MUC1 protein, human|*Mucin-1|Goblet Cells|Jejunum|Strongylida Infections|T Cells" 3 SLC25A34 18682385 J. Biol. Chem. 2008 PMC2661403 10.1074/jbc.M804637200 12 2 1 57 "Humans|*Saccharomyces cerevisiae|alpha-isopropylmalate|*Leucine|*Malates|*Mitochondria|Saccharomyces cerevisiae Proteins|*Yeast, Dried|citrate-binding transport protein|Carrier Proteins|Membrane Transport Proteins|Biological Transport|Isoleucine|Kinetics|*Biochemical Phenomena" 3 ZC3H12B 18178554 J. Biol. Chem. 2008 10.1074/jbc.M707861200 81 4 5 63 "*Macrophages|NOS2 protein, human|Inducible Nitric Oxide Synthase|Macrophage Activation|Lipopolysaccharides|Nuclear Factor-Kappab|Tumor Necrosis Factor-alpha|Cytokines|PHF20 protein, human|Signal Transduction|Nitric Oxide|Promoter Regions, Genetic|*Biomarkers, Tumor|Short Interfering RNA|Zinc Fingers" 3 C8orf17 18000363 Cytogenet. Genome Res. 2007 10.1159/000108293 13 0 0 23 "*Comparative Genomic Hybridization|Adenocarcinoma Of Esophagus|*Esophageal Neoplasms|*Adenocarcinoma|Esophagogastric Junction|Cardia|Stomach Neoplasms|Gene Amplification|*Disease Progression|RNA, Messenger|*Chromosome" 3 GTPBP6 17347996 Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007 PMC2094046 10.1002/ajmg.b.30454 29 0 0 11 "Humans|Male|Female|*Klinefelter Syndrome|*Genes, X-Linked|Chromosomes, Human, X|Phenotype|Gene Expression|*Cognition|Karyotyping|Karyotype" 3 IGHD2-2 17675554 Blood 2007 PMC2265453 10.1182/blood-2007-02-073130 15 0 0 0 "Humans|*Leukemia, Lymphocytic, Chronic, B-Cell|Heavy Chains, Immunoglobulin|Immunoglobulin Variable Region|Gene Rearrangement, B-Lymphocyte, Heavy Chain|Immunoglobulin Light Chains|Complementarity Determining Regions|B-Lymphocytes|Amino Acid Sequence|Multigene Family|Allele" 3 KIR3DX1 17579070 J. Immunol. 2007 10.4049/jimmunol.179.1.491 0 0 1 25 "Humans|Animals|*Pongo pygmaeus|*Haplotypes|*Receptors, KIR|*NK Cell Lectin-Like Receptor Subfamily D|*Pongo|HLA-C|Genes, MHC Class I|Nucleotide Sequence|Alleles|Evolution, Molecular|Phylogeny|Amino Acid Sequence|Pseudogenes|Primate|Killer Cells, Natural" 3 KIR3DX1 17450355 Immunogenetics 2007 10.1007/s00251-007-0214-x 29 0 2 25 "Cattle|Animals|*Killer Cell Immunoglobulin-Like Receptor|*Primates|Evolution, Molecular|Phylogeny|Amino Acid Sequence|Repetitive Sequences, Nucleic Acid|Receptors, Immunologic|Haplotypes|Histocompatibility Antigens Class I|Killer Cells, Natural" 3 METAP1D 17929833 Biochemistry 2007 10.1021/bi701127x 10 1 0 9 "Humans|*Kinetics|*Cations, Divalent|Escherichia coli|*Methionyl Aminopeptidases|aminopeptidase B|Aminopeptidases|Substrate Specificity|Binding Sites|Protein Conformation|Catalysis|Mutagenesis, Site-Directed|Crystallography, X-Ray|*Mutations|Active Site|Models, Molecular|Cobalt|Hydrogen-Ion Concentration|Methionine" 3 C19orf24 16847563 Cell. 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Genet. 2006 10.1007/s10528-006-9038-x 3 0 1 53 "Humans|Male|Mice|Adult|Animals|Rats|*Spermatogenesis|Testis|Infertility, Male|Sperm|cDNA Microarrays|cDNA|Amino Acid Sequence|Base Sequence|Transcription Factors|*Sex Differentiation|Gene Expression Regulation, Developmental|Sequence Homology, Amino Acid|Nucleic Acid Hybridization|RNA, Messenger|Open Reading Frame" 3 IGHD2-2 16402215 Immunogenetics 2006 10.1007/s00251-005-0062-5 7 0 2 0 "Humans|Reproducibility of Results|Immunoglobulin Heavy Chains|Immunoglobulin Joining Region|Genes, Immunoglobulin|Multigene Family|Bioinformatics|*Gene Expression|Gene Rearrangement|Databases, Nucleic Acid|Alleles|Mutations" 3 KIR3DX1 16911775 BMC Genomics 2006 PMC1559706 10.1186/1471-2164-7-209 22 1 1 25 "Humans|Animals|*Killer Immunoglobulin-Like Receptor|*Primates|Receptors, KIR2DL4|Amino Acid Sequence|Evolution, Molecular|Phylogeny|Multigene Family|Pan troglodytes|Sequence Homology, Amino Acid|Killer Cells, Natural|Cloning, Molecular|Receptors, Immunologic|DNA, Complementary" 3 SLC25A34 16949250 Genomics 2006 10.1016/j.ygeno.2006.06.016 57 0 3 57 "Animals|Humans|Rats|Mice|*Mitochondria|Mitochondrial Membrane Transport Proteins|Membrane, Mitochondrial|*Central Nervous System|Membrane Transport Proteins|Phylogeny|Biological Transport|Multigene Family|Saccharomyces cerevisiae|Brain|SLC25A32 protein, human|SLC25A39 protein, human|Slc25a38 protein, human|SLC25A43 protein, human|Tumor Suppressor Proteins|SLC25A46 protein, human|Mitochondrial Proteins|Phosphate Transport Proteins|Animals|Humans|Rats|Mice|*Mitochondria|Mitochondrial Membrane Transport Proteins|Membrane, Mitochondrial|*Central Nervous System|Membrane Transport Proteins|Phylogeny|Biological Transport|Multigene Family|Saccharomyces cerevisiae|Brain|SLC25A32 protein, human|SLC25A39 protein, human|Slc25a38 protein, human|SLC25A43 protein, human|Tumor Suppressor Proteins|SLC25A46 protein, human|Mitochondrial Proteins|Phosphate Transport Proteins" 3 AMZ2 15972818 J. 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Commun. 2004 10.1016/j.bbrc.2004.02.091 11 0 0 16 "Humans|Male|*Prostate Cancer|Prostate|*Downregulation|Northern Blot|Amino Acid Sequence|Genes, Tumor Suppressor|Base Sequence|Small GTPases|RNA, Messenger|Cloning, Molecular|gephyrin|Membrane Proteins|Genome Mapping|Sequence Homology, Amino Acid" 3 FRA10AC1 15203205 Genomics 2004 10.1016/j.ygeno.2003.12.017 18 0 0 42 "Male|*Nuclear Protein|*Folate|In Situ Hybridization, Fluorescence|*Chromosome Fragile Sites|Fragile X Syndrome|Chromosome Fragility|Trinucleotide Repeat|CpG Island|Allele|Gene Expression|Exons|Methylation" 3 NAT6 15276206 Gene 2004 10.1016/j.gene.2004.04.017 1 0 0 27 "Humans|Male|Swine|Mice|Animals|Base Sequence|Sequence Alignment|Cloning, Molecular|Exon|Amino Acid Sequence|DNA, Complementary|Gene Expression Profiling|NAT2 protein, human|Arylamine N-Acetyltransferase|DNA|Sequence Analysis, DNA|Minipigs|RNA, Messenger|Open Reading Frames|Polymorphism, Single Nucleotide|Sequence Homology, Amino Acid" 3 C8orf17 12665628 "MP, Mol. 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Acta 2001 10.1016/s0167-4781(01)00315-3 4 0 0 2 "Humans|*Actins|*cDNA|Amino Acid Sequence|Phylogeny|Sequence Homology, Amino Acid|Models, Molecular|Cytoplasm" 3 GTPBP6 11731500 Genome Res. 2001 PMC311231 10.1101/gr.197001 12 0 1 11 "Male|Mice|Humans|Animals|*Sex Chromosome|Chromosome Mapping|Cloning, Molecular|X Chromosome|Amino Acid Sequence|Sequence Homology, Nucleic Acid|Genome|Repetitive Sequences|Nucleic Acid Hybridization|Evolution, Molecular|Sequence Homology, Amino Acid|Pseudoautosomal Region|In Situ Hybridization, Fluorescence" 3 PAGE3 11751237 Bioinformatics 2001 10.1093/bioinformatics/17.12.1236 238 0 10 5 "*HLA-DR|*Binding Sites|Epitopes, T-Lymphocyte|Software|Histocompatibility Antigens Class I|Protein Binding|Computational Biology|Algorithm|Alleles|Computers" 3 PAGE3 11418000 Exp. Mol. Pathol. 2001 10.1006/exmp.2001.2377 15 8 1 5 "SPTBN1 protein, human|*Spectrin|*Hereditary Hemolytic Anemias|Elliptocytosis, Hereditary|Ankyrin|Erythrocyte Membrane|Protein Binding|Membrane Proteins|Erythrocyte|Binding Sites|Protein Structure, Secondary|*Actin Cytoskeleton|Mutation" 3 P12883 10973260 Nat. Genet. 2000 10.1038/79069 45 0 2 0 "Humans|MYH9-Related Disorders|*Myosin Heavy Chains|Giant Platelet Syndrome with Thrombocytopenia|*Thrombocytopenia|*Hearing Loss, Sensorineural|Molecular Motor Proteins|*Mutation|Blood Platelet Disorders|Genes, Dominant|Platelet|Phenotype|Pedigree|Megakaryocytes|Amino Acid Sequence|Syndrome|Leukocytes|MYH9 protein, human" 3 PYY2 10756099 Genomics 2000 10.1006/geno.2000.6132 1 0 0 0 "Humans|Cattle|Animals|Female|Rats|Mice|PPY protein, human|*Pancreatic Polypeptide|*Peptide YY|*Neuropeptide Y|Amino Acid Sequence|Nucleotide Sequence|*Species Specificity|Gene Cluster|Gene Duplication|Sequence Alignment|Sequence Homology, Amino Acid|PPY2P protein, human|Cloning, Molecular" 3 HHLA1 10329003 Genomics 1999 10.1006/geno.1999.5787 0 0 2 12 "Humans|Mice|Animals|*Endogenous Retroviruses|*RNA Splicing|Long Terminal Repeat|Amino Acid Sequence|Exons|Transcription, Genetic|Conserved Sequence|Phospholipases A2|Cloning, Molecular|Evolution, Molecular|RNA, Messenger" 3 TP53TG3 10534768 Genes Chromosomes Cancer 1999 8 0 0 2 "Humans|Male|*TP53 Gene|Amino Acid Sequence|Base Sequence|Tumor Suppressor Protein p53|Cloning, Molecular|Nuclear Proteins|Neoplasm Proteins|Antigens, Neoplasm|HeLa Cells|Testis|Gene Expression Regulation, Neoplastic|mRNA|Alternative Splicing|Display, mRNA Differential|DNA, Complementary|Transfection|TP53 protein, human" 3 GTPBP6 9466997 Hum. 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U.S.A. 1997 PMC20758 10.1073/pnas.94.9.4538 7 2 0 0 "Animals|Humans|*Ataxia Telangiectasia|*DNA Topoisomerases, Type I|*Phenotype|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|DNA|Sensitivity, Radiation|DNA-Binding Proteins|Cloning, Molecular|Cell Cycle|Cell Line|Transfection|Fibroblasts|Cultured Cells|cDNA|Cell Death" 3 GLI4 8641133 Cytogenet. Cell Genet. 1996 10.1159/000134207 3 0 0 19 "Humans|*In Situ Hybridization, Fluorescence|*Zinc|Zinc Finger|Transcription Factors|Repressor Proteins|Kruppel-Like Transcription Factors|Base Sequence|Chromosome Mapping|Amino Acid Sequence|Cloning, Molecular|DNA, Complementary|Genes, myc|*Chromosome Structures|Sequence Analysis, DNA" 3 P12883 8862525 Mol. Biol. Cell 1996 PMC275963 10.1091/mbc.7.7.1123 31 0 1 0 "Dictyostelium|*Myosin|Myosin Subfragments|Actins|Protein Conformation|Amino Acid Sequence|Binding Sites|Protein Binding|Models, Molecular|Kinetics|Adenosine Triphosphate|Phenotypes|Mutagenesis, Site-Directed|Mutagenesis" 3 P20142 8885407 "Microbiology (Reading, Engl.)" 1996 10.1099/13500872-142-10-2913 6 0 1 0 "*Yarrowia|Genes, Fungal|Amino Acid Sequence|alkaline protease|Fungal Proteins|Base Sequence|Transcription, Genetic|Cloning, Molecular|Serine Endopeptidases|Aspartic Acid Endopeptidases|Candida|*Gene Expression Regulation|Bacterial Proteins|Hydrogen-Ion Concentration" 3 P20142 8647118 Eur. J. 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Genet. 1994 10.1007/BF00202816 5 0 0 0 "Humans|Immunoglobulin Constant Regions|Genes, Immunoglobulin|Immunoglobulin Heavy Chains|IgG Deficiency|Haplotypes|Blotting, Southern|Immunoglobulin G|Gene Deletion|Pedigree|Tunisia|Italy|Sweden" 3 NAT6 7911085 Eur. J. Pharmacol. 1994 10.1016/0014-2999(94)90195-3 4 0 0 27 "Animals|Rabbits|*Thrombin Receptor|*Thrombin|*Synthetic Receptor|aminopeptidase B|*Aminopeptidases|amastatin|Peptides|Aminopeptidase M|Muscle Contraction|*Receptor, PAR-1|Muscle, Smooth, Vascular|Amino Acid Sequence|Aorta|Peptide Fragments|Structure-Activity Relationship" 3 P12883 8089177 J. Cell Biol. 1994 PMC2290954 10.1083/jcb.126.6.1445 133 1 2 0 Animals|Rabbits|ezrin|*Actins|radixin|*Cytoskeletal Proteins|*Protein Binding|moesin|Microfilament Proteins|Cytoskeleton|Binding Sites|Phosphoproteins|Amino Acid Sequence|Plasma Membrane|Schwannomin 3 PCAT4 7504406 Am. J. Hum. 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Rep. 2020 PMC7108035 10.3892/or.2020.7528 0 0 0 0 2 ANKRD30B 32303053 Neuropsychopharmacology 2020 10.1038/s41386-020-0675-2 0 0 0 1 "Humans|*Williams Syndrome|*DNA Methylation|*B-DNA|Epigenesis, Genetic|Phenotypes|Transcription Factors|Autism Spectrum Disorders|Neurogenesis|Gene Regulatory Networks|Gene Expression Profiles|Brain|*Biochemical Phenomena" 2 C11orf87 32179078 Microb. Pathog. 2020 10.1016/j.micpath.2020.104125 0 0 0 15 "MicroRNAs|Cell Movement|Cell Proliferation|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|*Macrophage|*Tuberculosis" 2 C11orf87 31959813 Sci Rep 2020 PMC6971273 10.1038/s41598-020-57467-z 0 0 0 15 "Humans|*Transcriptome Analysis|*Schizophrenia|*Fibroblasts|Transcriptome|Gene Regulatory Networks|Brain|Transcriptome Sequencing, Whole|Case-Control Studies|Genes, Regulator|Sweden|PRRT2 protein, human|Membrane Proteins|Nerve Tissue Proteins" 2 C1orf174 31927188 Hear. Res. 2020 PMC6996162 10.1016/j.heares.2019.107879 0 0 0 46 "Humans|Mice|Animals|*Genome-Wide Association Study|*Hearing|Presbycusis|Auditory Threshold|Evoked Potentials, Auditory, Brain Stem|Noise|*Hearing Tests|Mutation|DCLK1 protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins" 2 C5orf47 32592116 Mol. Biol. Rep. 2020 10.1007/s11033-020-05595-0 0 0 0 0 "Humans|Male|Mice|Animals|*Testis|*Spermatogenesis|*Fertility|Spermatozoa|Mice, Knockout|*Biological Evolution|Gene Expression|CRISPR-Cas Systems" 2 C9orf147 32420140 Transl Androl Urol 2020 PMC7214974 10.21037/tau.2020.01.29 0 0 0 0 2 CLEC18C 32306000 Beijing Da Xue Xue Bao 2020 0 0 0 2 "*Sorafenib|*Carcinoma, Hepatocellular|*Liver Neoplasms|Phenylurea Compounds|Niacinamide|Antineoplastic Agents|Drug Resistance, Neoplasm|Cell Line, Tumor|Cell Proliferation|Proto-Oncogene Proteins c-akt|Signal Transduction" 2 FAM151B 31949211 Sci Rep 2020 PMC6965129 10.1038/s41598-019-57398-4 0 0 0 87 "Animals|Mice|*Caenorhabditis elegans|*Retina|Retinal Degeneration|Electroretinography|Cyclic Nucleotide Phosphodiesterases, Type 6|Photoreceptor Cells, Vertebrate|Mice, Knockout|Eye Proteins|Animals|Mice|*Caenorhabditis elegans|*Retina|Retinal Degeneration|Electroretinography|Cyclic Nucleotide Phosphodiesterases, Type 6|Photoreceptor Cells, Vertebrate|Mice, Knockout|Eye Proteins" 2 FAM225A 32343052 Cancer Med 2020 PMC7300395 10.1002/cam4.3053 1 0 0 0 "*Colorectal Cancer|NOTCH3 protein, human|*Receptor, Notch3|Epithelial-Mesenchymal Transition|Gene Expression Regulation, Neoplastic|MicroRNAs|RNA, Long Noncoding|Cell Proliferation|*Disease Progression|Cell Movement|Apoptosis|Prognosis|*Neoplastic Processes|Nasopharyngeal Carcinoma|Cell Line, Tumor|*Colonic Neoplasms|Xenograft Model Antitumor Assays|Signal Transduction" 2 FAM30A 32411181 Front Genet 2020 PMC7199422 10.3389/fgene.2020.00382 0 0 0 15 "*RNA, Long Noncoding|*Plasma Cells|*Periodontitis|Gene Regulatory Networks|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Gene Ontology|Gene Expression Regulation, Neoplastic|Computational Biology|Downregulation|RNA, Messenger|Transcriptome|Signal Transduction" 2 GAGE10 31892350 Genome Med 2020 PMC6938636 10.1186/s13073-019-0693-z 1 0 0 0 "Humans|Female|Male|Adolescent|Young Adult|Adult|Middle Aged|Aged|Aged, 80 and over|*Epigenome|CpG Islands|DNA Methylation|*Aging|Epigenesis, Genetic|Genome-Wide Association Study|Genome, Human|Quantitative Trait Loci|Sex Differences" 2 GOLGA8B 32485038 J. 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Genet. 2020 PMC7015848 10.1093/hmg/ddz314 0 0 0 30 "*Transcriptome|Genome-Wide Association Study|*B-DNA|*Phenotype|Quantitative Trait Loci|Linkage Disequilibrium|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Gene Expression Profiling|*Lipids|Low Density Lipoprotein Cholesterol|Sequence Analysis, DNA" 2 wdr47 32320668 Cell Rep 2020 10.1016/j.celrep.2020.107526 0 0 0 34 "Animals|Mice|*Neurons|Microtubules|Microtubule-Associated Proteins|Axons|Neurites|Cytoskeletal Proteins|Cell Polarity|*Protein Binding|Hippocampus|Cells, Cultured|Central Nervous System|*Chromosome Segregation|Camsap3 protein, mouse" 2 ZMYM6 32025240 Infect. 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Biochem. 2019 10.1002/jcb.29063 2 0 0 0 "*RNA, Long Noncoding|*MicroRNAs|*mRNA|Prognosis|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Ontology|Transcriptome|Kaplan-Meier Estimate|*Laryngeal Neoplasms|*Squamous Cell Carcinoma of Head and Neck|Head and Neck Neoplasms" 2 AC024560.2 31315374 Zhonghua Yi Xue Za Zhi 2019 10.3760/cma.j.issn.0376-2491.2019.26.008 0 0 0 0 2 AC078883.3 31111480 J. Cell. Physiol. 2019 10.1002/jcp.28832 1 0 0 0 "*Cisplatin|*RNA, Long Noncoding|Carcinoma, Non-Small-Cell Lung|*Proto-Oncogene Proteins c-akt|*Drug Resistance, Neoplasm|Lung Neoplasms|PTEN protein, human|*PTEN Phosphohydrolase|*Signal Transduction|Cell Proliferation|Antineoplastic Agents|MicroRNAs|A549 Cells|Phosphatidylinositol 3-Kinases|Gene Expression Regulation, Neoplastic|Cell Line, Tumor|Apoptosis|Cell Movement" 2 AL357060.1 30989713 J. Cell. 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Neurooncol. 2017 10.1007/s11060-017-2667-6 14 0 0 0 "Humans|*RNA, Long Noncoding|*Glioma|Prognosis|Brain Neoplasms|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Biomarkers, Tumor|Kaplan-Meier Estimate" 2 LRRC3 28427458 Hum. Genomics 2017 PMC5397753 10.1186/s40246-017-0102-x 2 5 0 8 "Humans|*Polycythemia Vera|*Whole Exome Sequencing|Polycythemia, primary familial and congenital|JAK2 protein, human|Janus Kinase 2|Polycythemia|*Genotype|Myeloproliferative Disorders|Genetic Predisposition to Disease|Mutation" 2 RGAG4 28919299 Mol. Cell. Endocrinol. 2017 10.1016/j.mce.2017.09.013 0 0 0 2 "Mice|Animals|*Retroelements|*gag Protein|*Gland, Pituitary|C-terminal binding protein|DNA-Binding Proteins|*Pituitary Diseases|Ikaros Protein|Promoter Regions, Genetic|*Protein Domain|Alcohol Oxidoreductases|Zinc Finger|Chromatin|Gene Expression|Mice, Knockout" 2 RSU1P2 28849103 Oncol. Rep. 2017 10.3892/or.2017.5905 13 0 0 0 "Humans|Female|*Long Non-Coding RNA|*Uterine Cervical Neoplasms|Prognosis|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Disease Progression" 2 SCRN3 28679164 Biol. Reprod. 2017 10.1093/biolre/iox064 1 1 0 7 "Humans|Pregnancy|Female|Animals|Cattle|*Placenta|*Fetus|Genomic Imprinting|Intrauterine Growth Restriction|*Prenatal Care|DNA Methylation|Gene Expression Regulation, Developmental|Kruppel-Like Transcription Factors|Transcriptome Analysis|Transcriptome|Mutation" 2 TMEM256 28386932 J. Fish Biol. 2017 10.1111/jfb.13308 0 0 0 16 "Animals|*Real-Time Polymerase Chain Reaction|*Fishes|Genes, Essential|Gene Expression Profiling" 2 uniprot:null 28145583 J. Cell. Biochem. 2017 10.1002/jcb.25920 0 0 0 0 Humans|*Filamins|Larsen Syndrome|*Osteochondrodysplasias|Phenotype|Mutation 2 VWA3B 28985340 DNA Res. 2017 PMC5824824 10.1093/dnares/dsx037 3 1 0 3 "Cattle|Mice|Animals|Quantitative Trait Loci|Genome-Wide Association Study|*Genome Mapping|Breeding|*Genetics, Population|Polymorphism, Single Nucleotide|Fertility|Phenotype|Genomics" 2 wdr47 29078390 Proc. Natl. Acad. Sci. U.S.A. 2017 PMC5676932 10.1073/pnas.1713625114 13 0 0 34 "Animals|Mice|*Microtubule-Associated Proteins|*WD40 Repeat|Neurons|*Autophagy|Dyneins|1-Alkyl-2-acetylglycerophosphocholine Esterase|Microtubules|Neurogenesis|Cell Movement|Cells, Cultured|Brain" 2 ZFHX2 29253101 Brain 2017 PMC5837393 10.1093/brain/awx326 8 0 0 20 "Mice|Humans|Animals|*Point Mutation|Quality of Life|Pain Threshold|*Pain|Ganglia, Dorsal Root|Sensory Neurons|Mice, Transgenic|Hyperalgesia|Mice, Inbred C57BL|Pain Measurement|Mice, Knockout|Gene Expression Regulation|Disease Models, Animal|Action Potentials|Physical Stimulation" 2 AC024560.2 27035672 Oncol. Rep. 2016 PMC4869942 10.3892/or.2016.4715 22 1 1 0 "Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|*Lymphatic Metastasis|Prognosis|Biomarkers, Tumor|Carcinoma, Squamous Cell|Neoplasm Staging|Gene Expression Regulation, Neoplastic|Gene Expression Profiling|Kaplan-Meier Estimate|*Neck|Lymph Nodes" 2 ACTR3C 27312686 Laryngoscope 2016 10.1002/lary.26063 3 0 0 27 "*Keloid|*DNA Methylation|CpG Islands|*Genome|Epigenesis, Genetic|Promoter Regions, Genetic|Gene Expression Profiling|Case-Control Studies" 2 ACTR3C 26990118 Laryngoscope 2016 10.1002/lary.25958 3 0 0 27 "*Keloid|CpG Islands|DNA Methylation|Promoter Regions, Genetic|*Head|*Neck" 2 C12orf66 27609023 BMC Med Genomics 2016 PMC5016995 10.1186/s12920-016-0218-1 19 0 1 15 Humans|*Transcriptome|*Colorectal Cancer|*Colonic Neoplasms|Prognosis|Neoplasm Staging|Oligonucleotide Array Sequence Analysis|Disease-Free Survival|Gene Expression Profiling 2 EXD3 27881521 BMJ Open 2016 PMC5168545 10.1136/bmjopen-2016-011768 15 0 0 6 "Pregnancy|Humans|Female|Young Adult|Adult|*Cohort Studies|Diabetes Mellitus, Type 2|*Famine|Bangladesh|Starvation|Obesity|Body Mass Index|Prenatal Exposure Delayed Effects|Odds Ratio|Risk Factors|*Rural Population|Epigenesis, Genetic" 2 FAM76B 27018871 PLoS ONE 2016 PMC4809503 10.1371/journal.pone.0152237 1 0 1 23 "Humans|Mice|Animals|*Antibodies, Monoclonal|*Nuclear Protein|HEK293 Cells|Hybridomas|Antibody Specificity|Western Blot|Enzyme-Linked Immunosorbent Assay|*Cell Nucleus|Amino Acid Sequence|Immunofluorescence|Immunoprecipitation|*Antineoplastic Agents, Immunological" 2 GDPD4 27421018 Genet. Mol. Res. 2016 10.4238/gmr.15028311 4 0 0 2 "Adult|Humans|Child|*Whole Exome Sequencing|Genome-Wide Association Study|*Exome|Diabetes Mellitus, Type 2|Thailand|*Obesity|Body Mass Index|Asian Continental Ancestry Group|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Allele Frequency|Genotype|Proteins|Case-Control Studies|ALOX5AP protein, human|5-Lipoxygenase-Activating Proteins|FTO protein, human|Alpha-Ketoglutarate-Dependent Dioxygenase FTO" 2 GOLGA8A 26738811 J Stroke Cerebrovasc Dis 2016 10.1016/j.jstrokecerebrovasdis.2015.11.032 0 0 0 49 Humans|*Cerebral Hemorrhage|Cerebral Amyloid Angiopathy|Stroke|Hypertension|*Biomarkers|*Plasma 2 LINC00636 26929647 Onco Targets Ther 2016 PMC4758788 10.2147/OTT.S97664 32 3 2 4 "Humans|Female|*RNA, Long Noncoding|ERBB2 protein, human|*Computational Biology|*Receptor, ErbB-2|*Sequencing, Next-Generation|*Oncogenes|Gene Expression Profiling|mRNA|Gene Expression Regulation, Neoplastic|Tumorigenesis" 2 MIR513C 27910778 J. Environ. Pathol. Toxicol. Oncol. 2016 10.1615/JEnvironPatholToxicolOncol.2016016320 0 3 0 0 "Humans|*Methyl-CpG-Binding Protein 2|*Genotype|DNA methyltransferase 3B|*DNA (Cytosine-5-)-Methyltransferases|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|DNA Methylation|*Lung|Promoter Regions, Genetic|miRNAs|Allele|MIRN3202 microRNA, human" 2 MTRNR2L8 26769839 J. Physiol. Pharmacol. 2016 4 1 0 40 Humans|*Coronary Artery Disease|*Hyperoxia|*Upregulation|*Pilot Projects|humanin|Coronary Artery Bypass Grafting|*Myocardium|Heart|*Transcriptional Activation|Oxygen 2 nfd1 26954254 PLoS ONE 2016 PMC4783078 10.1371/journal.pone.0150463 0 4 1 0 "Humans|Cats|Mice|Animals|*Liposomes|*BALB C Mice|*Allergic Rhinitis|*Administration, Intranasal|*Adjuvants, Immunologic|*Vaccines|Allergens|*Felis|Immunoglobulin E|Nasal Mucosa|Ovalbumin|*Adjuvants, Pharmaceutic|*Disease Models, Animal|Cytokines" 2 PCDHGA2 27811364 Oncotarget 2016 PMC5340256 10.18632/oncotarget.13019 0 5 0 18 "Humans|DNA Copy Number Variations|ERBB2 protein, human|*Receptor, ErbB-2|Carcinoma, Lobular|*Cadherins|Carcinoma, Ductal, Breast|*Mutation|Neoplasm Invasiveness|Lymphatic Metastasis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic|PTEN protein, human|PTEN Phosphohydrolase|herstatin|*Intercellular Signaling Peptides and Proteins|*Breast Cancer|Prognosis|CDH1 protein, human" 2 RPUSD3 27974379 EMBO Rep. 2016 PMC5210091 10.15252/embr.201643391 25 0 0 31 "pseudouridine synthases|*Cell Survival|RNA, Ribosomal, 16S|*Intramolecular Transferases|Pseudouridine|mitochondrial messenger RNA|Mitochondrial RNA|RNA Modification, Post-Transcriptional|RNA, Messenger|*Protein Biosynthesis|RNA, Ribosomal|Mitochondrial Ribosome|Saccharomyces cerevisiae|Oxidative Phosphorylation|Mitochondrial Proteins" 2 RPUSD3 27667664 Cell Metab. 2016 PMC5474757 10.1016/j.cmet.2016.08.017 52 7 0 31 "Humans|*Oxidative Phosphorylation|*Clustered Regularly Interspaced Short Palindromic Repeats|RNA, Ribosomal, 16S|*Genome|Mitochondria|Mitochondrial Proteins|RNA, Mitochondrial|Protein Biosynthesis|RNA, Ribosomal|Cell Nucleus|Cell Line" 2 RSU1P2 27487126 Oncotarget 2016 PMC5546439 10.18632/oncotarget.10844 30 40 0 0 "Humans|Female|*RNA, Long Noncoding|*Uterine Cervical Neoplasms|RNA, Micro|Gene Expression Regulation, Neoplastic|Cell Transformation, Neoplastic|*Tumorigenesis|Proto-Oncogene Proteins c-myc|Cell Proliferation|Cell Cycle|Cell Line, Tumor|Apoptosis" 2 SLC35F4 27716579 Aquat. Toxicol. 2016 PMC5274700 10.1016/j.aquatox.2016.09.019 3 6 0 1 "Animals|*Zebrafish|Zebrafish Proteins|NFE2L2 protein, human|NF-E2-Related Factor 2|*Oxidative Stress|Embryo, Nonmammalian|*Oxidation-Reduction|Embryonic Development|Gene Expression Regulation, Developmental|Pro Oxidants|Antioxidants|GA-Binding Protein Transcription Factor|Animals, Genetically Modified|Larvae" 2 STPG2 27934915 Sci Rep 2016 PMC5146968 10.1038/srep38803 14 1 0 3 "Humans|Floating-harbor syndrome|*DNA Methylation|*Craniofacial Abnormalities|*Abnormalities, Multiple|*Heart Septal Defects, Ventricular|*Growth Disorders|Mutations|Dwarfism|Adenosine Triphosphatases|*Nucleotide Motifs|CpG Islands|Face|Chromatin|MYO1F protein, human|Myosin Type I" 2 TMEM256 27664330 Eur J Pharm Sci 2016 10.1016/j.ejps.2016.09.023 18 0 0 16 "Humans|Male|*Prostate|*Cancer Biomarkers|*Prostate Cancer|Exosomes|*Mass Spectrometry|TYRP1 protein, human|*Membrane Glycoproteins|Receiver Operating Characteristic|*Immunoassay|Cell Line, Tumor|Proteome|Specificity|Urinalysis" 2 TRBJ2-3 26953160 Diabetes 2016 PMC5310213 10.2337/db15-1498 4 11 0 0 "Humans|Mice|Animals|*Proinsulin|*Insulin|*CD8-Positive T-Lymphocytes|*NOD Mice|*Insulin, Regular, Human|Diabetes Mellitus, Type 1|Receptors, Antigen, T-Cell, alpha-beta|Genes, T-Cell Receptor beta|Islets of Langerhans|T Cell Receptor|Mice, Transgenic" 2 TRGJ2 27528257 BMC Genomics 2016 PMC4986337 10.1186/s12864-016-2841-9 6 4 1 0 "Animals|Humans|*Bottle-Nosed Dolphin|Ecosystem|*Receptors, Antigen, T-Cell, gamma-delta|*Genome|*Genomics|Receptors, Antigen, T-Cell, alpha-beta|Amino Acid Sequence" 2 ZNF628 27940565 Physiol. Genomics 2016 10.1152/physiolgenomics.00069.2016 8 0 0 4 Female|Swine|Animals|*Follicular Atresia|*Gene Regulatory Networks|*Ovary|Ovarian Follicles|Granulosa Cells|Transcriptome Analysis|Apoptosis|Microarray Analysis 2 ABHD17B 26701913 Elife 2015 PMC4755737 10.7554/eLife.11306 53 38 1 69 "Palmitoylation|TYRP1 protein, human|*Membrane Glycoproteins|*Palmitates|Thiolester Hydrolases|Protein Transport|palmostatin B|Propiolactone|Cell Membrane|ras Proteins|Signal Transduction|Postsynaptic Density Protein 95|Protein Processing, Post-Translational|Cysteine|Hydrolases|Cytosol" 2 AC002454.1 26618670 Cell. Physiol. Biochem. 2015 10.1159/000438579 15 2 1 0 Humans|Female|*Long Non-Coding RNA|*Endometriosis|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Signal Transduction|Endometrium 2 AGAP4 25706777 Radiat. Res. 2015 10.1667/RR13758.1 2 0 1 5 "Humans|Male|Female|Cross-Sectional Studies|Plutonium-239|Plutonium|Occupational Exposure|Nuclear Power Plants|Radiation Exposure|*Gene Expression|Radiation Injuries|Gamma Rays|MIRN92 microRNA, human|MicroRNAs|Radiation Dosage|*Chronic Diseases|mRNA|Odds Ratios" 2 C5orf47 26616883 J. Neuroimmunol. 2015 10.1016/j.jneuroim.2015.11.002 0 0 0 0 Humans|*Neuromyelitis Optica|*Exome|Aquaporin 4|Autoantibodies|*Regulatory Region|Finland 2 calmodulina 26048625 Rheumatol. Int. 2015 10.1007/s00296-015-3303-4 0 0 0 0 "Male|Humans|Middle Aged|Female|*Arthritis, Psoriatic|*Hyperostosis, Diffuse Idiopathic Skeletal|Antirheumatic Agents|Psoriasis|Waist Circumference|Body Mass Index|Tumor Necrosis Factor-alpha|Risk Factors|Spine|Cohort Studies|Prevalence|Italy" 2 CCDC178 26330360 Sci Rep 2015 PMC4557136 10.1038/srep13750 23 3 4 6 "*Stomach Neoplasms|*Transcriptome|Neoplasm Recurrence, Local|*Peritoneum|Peritoneal Neoplasms|*Whole Exome Sequencing|Gene Expression Regulation, Neoplastic|Transcriptome Analysis|Oligonucleotide Array Sequence Analysis|Mutation|*Carcinoma|China" 2 CLEC18C 26170455 J. Biol. Chem. 2015 PMC4571857 10.1074/jbc.M115.649814 5 2 0 2 "Humans|*Lectins, C-Type|*Gene Cluster|Sequences, Amino Acid|fucoidan|Polysaccharides|Binding Sites|*Specificity" 2 FAM122B 25735772 Bioinformatics 2015 PMC4495292 10.1093/bioinformatics/btv133 38 2 2 52 "*Phosphopeptides|prednylidene|Sequence Analysis, Protein|*Prednisolone|Proteome|Phosphoproteins|Amino Acid Sequence|Amino Acid Motifs|Phosphorylation|Proteomics|Software|Protein Binding|*Prednisone|*Phosphopeptides|prednylidene|Sequence Analysis, Protein|*Prednisolone|Proteome|Phosphoproteins|Amino Acid Sequence|Amino Acid Motifs|Phosphorylation|Proteomics|Software|Protein Binding|*Prednisone" 2 FAM122B 26416664 J Transl Med 2015 PMC4587873 10.1186/s12967-015-0669-8 5 7 1 52 "*Mesenchymal Stem Cells|*Telocytes|*Alveolar Epithelial Cells|*Lung|*Fibroblasts|*Lymphocytes|*Cells, Epithelial|Gene Expression Profiles|*Genes, X-Linked|Interstitial Cells of Cajal|Stem Cells|*Cell Count|Chromosomes" 2 FAM135A 25991709 Physiol. Genomics 2015 PMC4525077 10.1152/physiolgenomics.00114.2014 9 0 0 43 "Humans|Mice|Animals|*Quantitative Trait Locus|*Chromosomes, Human, Pair 1|Genome-Wide Association Study|Chromosome Mapping|Chromosomes, Mammalian|Mice, Inbred C57BL|Phenotypes|Ethanol|Gene Expression Profiling" 2 FSD1L 25733798 Cancer Inform 2015 PMC4332043 10.4137/CIN.S17289 0 1 0 23 "*Epistasis, Genetic|Genome-Wide Association Study|Linkage Disequilibrium|Single Nucleotide Polymorphisms|Logistic Regression|Models, Genetic|Computational Biology|Computer Simulation|Algorithms|*Head and Neck Cancer" 2 GLT8D2 25952508 Lipids Health Dis 2015 PMC4425853 10.1186/s12944-015-0040-3 4 5 1 28 "Nonalcoholic Fatty Liver Disease|Sterol Regulatory Element Binding Protein 1|Liver|Hepatocytes|Hep G2 Cells|PPAR alpha|Diet, High-Fat|Triglycerides|*Glycosyltransferases" 2 HHLA3 25676578 Reprod Sci 2015 PMC4565480 10.1177/1933719115570903 7 0 2 13 "Pregnancy|Female|Humans|*Diabetes, Gestational|*DNA Methylation|*B-DNA|*Pilot Projects|Epigenesis, Genetic|Parturition|DNA" 2 IQCA1 25669608 Heredity (Edinb) 2015 PMC4434252 10.1038/hdy.2015.3 7 0 3 5 "Animals|Carps|*B-DNA|Carassius auratus|Diploid|Hybridization, Genetic|*Genomics|Polyploidy|Base Sequence|Chimera|DNA" 2 KCTD19 26466362 PLoS ONE 2015 PMC4605695 10.1371/journal.pone.0140404 4 7 2 2 "Humans|*HIV-1|*Down-Regulation|HeLa Cells|nef Gene Products, Human Immunodeficiency Virus|*Genes, MHC Class I|HIV Infections|HLA-A2|Clathrin|*HIV Seropositivity|Protein Transport|SLC6A3 protein, human|Dopamine Plasma Membrane Transport Proteins|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1|Camsap3 protein, human|Microtubule-Associated Proteins" 2 KCTD19 26350515 Eur. 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Neurol. Neurosurg. Psychiatry 2015 10.1136/jnnp-2014-309828 6 0 1 3 *Cerebellar Ataxia|*Intellectual Disability|*Homozygote|*Mutation|Pedigree|Spinocerebellar Degenerations|Phenotype|Japan 2 C4orf22 24739539 Hypertens. Res. 2014 10.1038/hr.2014.84 5 0 1 7 "Humans|Mice|Animals|*Blood Pressure|*Genome-Wide Association Study|Hypertension|*Blood Pressure Determination|Single Nucleotide Polymorphism|Genetic Loci|Genetic Predisposition to Disease|Asians|FGF5 protein, human|Fibroblast Growth Factor 5|mRNA|RNA, Small Interfering|Ethnic Groups|ANTXR2 protein, human|Receptors, Peptide|Antxr2 protein, mouse|PRDM8 protein, mouse|Histone-Lysine N-Methyltransferase" 2 EBLN2 24954872 Lung Cancer 2014 10.1016/j.lungcan.2014.05.020 6 0 1 7 "Humans|*Germ-Line Mutation|Genome-Wide Association Study|*Non-Smokers|*Lung Adenocarcinoma|Lung Cancer|Adenocarcinoma|Genetic Predisposition to Disease|Carcinoma, Squamous Cell|Genotype|Biomarkers, Tumor|Smoking" 2 FAM151B 25271210 Physiol. Genomics 2014 PMC4233283 10.1152/physiolgenomics.00091.2014 9 0 0 87 "Rats|Animals|Rats, Otsuka-Long-Evans-Tokushima|*Obesity|*Arteries|Soleus Muscle|Arterioles|Vasodilation|Sequencing, RNA|Transcriptome" 2 MIR525 25390694 PLoS ONE 2014 PMC4229240 10.1371/journal.pone.0112646 1 0 0 0 "Humans|*3' Untranslated Regions|*Polymorphism, Single Nucleotide|HEK293 Cells|miRNA|Allele|Genetic Predisposition to Disease|Gene Expression Regulation|Binding Sites|RNA, Messenger|*Gene Expression|Genes, Reporter|Luciferase|MIRN525 microRNA, human" 2 MIR634 25371140 Mol Med Rep 2014 10.3892/mmr.2014.2837 5 0 0 0 "*Computational Biology|*Parkinson Disease|miRNAs|Gene Regulatory Networks|mRNA|Databases, Genetic|Gene Expression Profiling|Gene Annotations|Gene Expression Regulation, Neoplastic|Transcriptome|Biomarkers|Signal Transduction|Gene Ontology|Mitogen-Activated Protein Kinases" 2 P15085 25488368 Insect Mol. 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Photobiol. 2013 10.1111/php.12063 1 0 0 0 "Humans|*Lens, Crystalline|Proteins, Lens|beta-crystallin B2|beta-Crystallin B Chain|Two Dimensional Gel Electrophoresis|*Lenses|Ultraviolet Radiation|Mass Spectrometry|Chromatography, Gel|Proteomics|alpha-Crystallin A Chain" 2 SNORD96B 23520119 Am. J. Med. Genet. A 2013 10.1002/ajmg.a.35778 5 0 0 0 "Humans|Male|Child|Alport Syndrome, Mental Retardation, Midface Hypoplasia, and Elliptocytosis|*Intellectual Disability|Chromosome Deletion|Alport Syndrome|Craniofacial Abnormalities|Abnormalities, Multiple|Genetic Diseases, X-Linked|Chromosomes, Human, X|Elliptocytosis, Hereditary|Phenotype|Chromosome Aberrations|In Situ Hybridization, Fluorescence|*Chromosome Structures|AMMECR1 protein, human|Proteins" 2 TMEM164 23520119 Am. J. Med. Genet. 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Microbiol. 2008 10.1099/jmm.0.000034-0 18 0 1 0 "*Salmonella enteritidis|*Bacteriophages|*Phage Typing|Salmonella Phages|Siphoviridae|Myoviridae|Genome, Viral|Sequence Analysis, DNA|Base Sequence|Podoviridae|London|*Salmonella enteritidis|*Bacteriophages|*Phage Typing|Salmonella Phages|Siphoviridae|Myoviridae|Genome, Viral|Sequence Analysis, DNA|Base Sequence|Podoviridae|London|*Salmonella enteritidis|*Bacteriophages|*Phage Typing|Salmonella Phages|Siphoviridae|Myoviridae|Genome, Viral|Sequence Analysis, DNA|Base Sequence|Podoviridae|London" 2 SLC25A35 18682385 J. Biol. Chem. 2008 PMC2661403 10.1074/jbc.M804637200 12 2 1 11 "Humans|*Saccharomyces cerevisiae|alpha-isopropylmalate|*Leucine|*Malates|*Mitochondria|Saccharomyces cerevisiae Proteins|*Yeast, Dried|citrate-binding transport protein|Carrier Proteins|Membrane Transport Proteins|Biological Transport|Isoleucine|Kinetics|*Biochemical Phenomena" 2 C11orf80 18160775 Cytogenet. 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Patterns 2018 PMC6136450 10.1016/j.gep.2018.07.002 0 0 0 3 "Animals|*Zebrafish|Agenesis of Cerebellar Vermis|Kidney Diseases, Cystic|Eye Abnormalities|Zebrafish Proteins|Cilia|Abnormalities, Multiple|ADP-Ribosylation Factors|Retina|Retinal Degeneration|Cerebellum|Mutation|Microtubules|Arl13b protein, zebrafish" 1 Bhlhe23 29615777 Sci Rep 2018 PMC5883057 10.1038/s41598-018-23901-6 3 12 0 7 Animals|*Night Vision|*Transcriptome|*Retinal Bipolar Cells|Retinal Rod Photoreceptor Cells|*Dark Adaptation|Retina 1 C14orf37 29850813 Genome Biol Evol 2018 PMC6007540 10.1093/gbe/evy102 9 1 0 28 Animals|*Trout|Animal Migration|Salmonids|Freshwater|Seawater|SNPs 1 C1orf54 29999589 J. Cell. Mol. Med. 2018 PMC6156286 10.1111/jcmm.13765 2 2 0 4 "Humans|Mice|Animals|Phosphatidylinositol 3-Kinases|*Acute Kidney Injury|Ischemia-Reperfusion Injury|Kidney Tubules|Kidney|Signal Transduction|Mice, Knockout|Epithelial Cells|Apoptosis|Cell Proliferation|Kidney Glomerulus|Cell Line" 1 C2orf83 30343302 Gynecol. 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Pathol. 2018 10.1016/j.humpath.2018.08.007 1 0 0 14 "Humans|*Proto-Oncogene Proteins p21(ras)|Neoplasm Recurrence, Local|*Colorectal Cancer|*Prognosis|*Downregulation|Disease-Free Survival|Biomarkers, Tumor|Kaplan-Meier Estimate|Immunohistochemistry|Gene Expression Regulation, Neoplastic|*Colonic Neoplasms|Mutation|KRAS protein, human" 1 PGCP1 30172742 Bone 2018 PMC6364698 10.1016/j.bone.2018.08.020 1 4 0 0 "Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Osteoporosis|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Genetic Pleiotropy|Bone Density|Gene Regulatory Networks" 1 POTEG 29566278 Mol. 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Genome Res. 2018 10.1159/000488162 1 0 0 0 "Humans|Male|Aged|Child, Preschool|*Chromosomes, Human, Y|*Mosaicism|*Hypospadias|Karyotyping|Sex Chromosome Aberrations|Karyotype|In Situ Hybridization, Fluorescence|*Diploidy" 1 Q5T5C0 29485200 FEBS Lett. 2018 10.1002/1873-3468.13018 3 2 0 0 "Syntaxin 1|SNAP25 protein, human|Synaptosomal-Associated Protein 25|UNC13B protein, human|*Nerve Tissue Proteins|Synaptobrevin 2|Munc18 Proteins|R-SNARE Proteins|Exocytosis|Membrane Fusion|Syntaxin|Synaptic Transmission|*Cytoplasm|Protein Binding|Binding Protein|Cell Membrane" 1 RP4-794H19.1 29896278 J Cancer 2018 PMC5995947 10.7150/jca.23481 3 1 0 0 1 RP4-799D16.1 29531791 RMD Open 2018 PMC5845418 10.1136/rmdopen-2017-000628 0 8 0 0 "*Spondylitis, Ankylosing|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Core Binding Factor Alpha 3 Subunit|Genotype|Case-Control Studies" 1 SETP5 30280788 Eur Rev Med Pharmacol Sci 2018 10.26355/eurrev_201809_15940 0 6 0 0 "PTEN protein, human|*PTEN Phosphohydrolase|*Stroke|Phosphatidylinositol 3-Kinases|Long Non-Coding RNA|Proto-Oncogene Proteins c-akt|MicroRNAs|Signal Transduction|Apoptosis|Cell Proliferation|Reperfusion Injury|*Cell Death|Neurons" 1 TRAJ39 29997305 JCI Insight 2018 PMC6124526 10.1172/jci.insight.120682 6 1 0 0 "Humans|IL17A protein, human|*Interleukin-17|*Psoriasis|Skin|Imiquimod|Keratinocytes|*Sequencing, RNA|Cytokines|*Base Sequence|T-Lymphocytes|*Whole Exome Sequencing" 1 TRBV6-7 29385144 PLoS ONE 2018 PMC5791954 10.1371/journal.pone.0178167 1 0 0 0 "Humans|Female|*Human Papilloma Virus|*Papillomavirus Infections|HPV 16|Cervical Intraepithelial Neoplasia|Human papillomavirus 18|Uterine Cervical Neoplasms|Vaginal Smears|DNA, Viral|Receptors, Antigen, T-Cell" 1 YBX3P1 29729044 Indoor Air 2018 10.1111/ina.12472 0 0 0 0 "*Transcriptome|Leukocytes, Mononuclear|Air Pollution, Indoor|Fungi|Asthma|Humidity|*Nasal Mucosa|Schools" 1 A2MP1 28073367 Respir. 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Cancer Res. 2017 10.1158/1541-7786.MCR-17-0191 6 2 0 0 "*Nonsmall Cell Lung Cancer|Lung Cancer|*DNA Methylation|Epigenesis, Genetic|RNA, Long Noncoding|Gene Expression Regulation, Neoplastic|Cell Proliferation|Cell Line, Tumor|Gene Expression Profiling|*Regulatory Genes|Promoter Regions, Genetic|Tumorigenesis|Lung|Cell Transformation, Neoplastic" 1 AL355149.1 31966382 Int J Clin Exp Pathol 2017 PMC6965784 3 0 0 0 "Humans|*Rheumatoid Arthritis|Erythrocyte Sedimentation Rate|Long Non-Coding RNA|Biomarkers|C-Reactive Protein|ITSN1 protein, human|*Adaptor Proteins, Vesicular Transport|Receiver Operating Characteristic|Area Under Curve" 1 ANKRD20A2 29054765 Gene 2017 10.1016/j.gene.2017.10.020 6 0 0 0 "Humans|*Germ-Line Mutation|DNA Copy Number Variations|*Lung Cancer|Carcinoma, Non-Small-Cell Lung|Genetic Susceptibility|*Chinese|Oncogenes|Mutation|Pedigree|DNA Sequencing|Smoking" 1 C10orf128 29081410 Cancer Biomark 2017 10.3233/CBM-170541 0 0 0 0 "Humans|*Basal Cell Nevus Syndrome|*Whole Exome Sequencing|PTCH2 protein, human|Patched-2 Receptor|*Chinese|Patched-1 Receptor|Exome|Pedigree|Mutation|Genetic Linkage" 1 C1orf87 28282151 J. Proteome Res. 2017 PMC5733142 10.1021/acs.jproteome.6b00972 19 1 0 29 Humans|*Cilia|*Proteomics|Axoneme|*Proteins|Dyneins|Tubulin|*Respiratory System 1 C4orf19 29271998 Eur Rev Med Pharmacol Sci 2017 10.26355/eurrev_201712_14008 2 0 0 28 1 C7orf73 28809398 Mol. Psychiatry 2017 PMC5582166 10.1038/mp.2017.128 13 1 0 67 "Humans|Female|Male|*Suicide|*Precision Medicine|Suicidal Ideation|Suicide, Attempted|Bipolar Disorder|Gene Expression|Risk Assessment|Risk Factors|Biomarkers|Gene Expression Profiling|Anxiety Disorders|Genomics|Cohort Studies|Bioinformatics|Future|SKA2 protein, human|Chromosomal Proteins, Non-Histone" 1 C8orf44 28569192 BMC Genomics 2017 PMC5452331 10.1186/s12864-017-3811-6 2 0 0 2 Humans|*mRNA|*Binding Sites|3' Untranslated Regions|miRNA 1 LGALS16 28647356 Reprod. Biomed. 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Med. 2017 PMC5706512 10.1111/jcmm.13288 8 0 0 0 "Humans|Female|*Uterine Cervical Neoplasms|*Papillomavirus Infections|HeLa Cells|Human papillomavirus 18|Oncogene Proteins, Viral|Human papillomavirus 16|Papillomavirus E7 Proteins|Long Non-Coding RNA|Repressor Proteins|Gene Expression Regulation, Viral|DNA-Binding Proteins|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|siRNA|Oncogene|Signal Transduction" 1 MIR4262 28731150 Mol Med Rep 2017 PMC5646949 10.3892/mmr.2017.7057 4 15 0 0 "*Cell Proliferation|*Colon Cancer|MicroRNAs|Downregulation|Gene Expression Regulation, Neoplastic|Neoplasm Invasiveness|Cell Movement|Upregulation|mRNA|Cell Line, Tumor|Gene Knockdown Techniques|Viability, Cell|Cell Cycle" 1 NACC2 28589857 BMC Med Genomics 2017 PMC5461531 10.1186/s12920-017-0269-y 11 20 0 230 "*DNA Methylation|*Urinary Bladder Neoplasms|*miRNA|*Prognosis|Epigenesis, Genetic|*Epigenetic|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Transcriptome|Cell Line, Tumor" 1 P50453 28296156 J. Cell. Mol. Med. 2017 PMC5571515 10.1111/jcmm.13127 3 6 0 0 Humans|*Endothelial Cells|bcl-Associated Death Protein|Apoptosis|Proto-Oncogene Proteins c-akt|Caspase 3|Signal Transduction|Phosphorylation|Enzyme Activation|Cell Survival|*Cell Death 1 Q5EBN2 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human|Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q6ZMN7 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human|Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q7L622 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q8N5U6 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q8N653 28786561 FEBS J. 2017 10.1111/febs.14193 0 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q96M94 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 q96q07 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q96QU1 28495838 J. Cell Biol. 2017 PMC5461027 10.1083/jcb.201612030 3 9 0 0 Humans|*Usher Syndromes|*Cadherins|Retinal Cone Photoreceptor Cells|Retina|Rod Cell Outer Segment|Retinal Dystrophy|*Cilia|*Neurites 1 Q99592 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q9BWX1 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q9NXI6 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q9NZS9 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 Q9P275 28786561 FEBS J. 2017 10.1111/febs.14193 13 3 0 0 "Humans|*Proteasome Endopeptidase Complex|*Ubiquitin|*Papillomavirus Infections|*Papillomavirus E7 Proteins|*Oncogene Proteins, Viral|Human papillomavirus 16|Repressor Proteins|Ubiquitination|E3 Ubiquitin Ligase|Protein Binding|Immunity, Innate|*Cytoplasm|TNFAIP1 protein, human|Proteins|USP33 protein, human|Ubiquitin Thiolesterase|MGRN1 protein, human|RNF135 protein, human" 1 RNA5SP455 28642868 Int J Genomics 2017 PMC5470022 10.1155/2017/7208318 4 7 0 0 "Humans|Genome-Wide Association Study|*Epistasis, Genetic|*Hypertension|Blood Pressure|Polymorphism, Single Nucleotide|Genetic Predisposition to Disease|Genotype|Genome, Human|Phenotype|Cohort Studies|Framingham Heart Study" 1 RPL13AP7 29657277 Noncoding RNA 2017 PMC5831999 10.3390/ncrna3010005 9 0 0 0 "Adult|Humans|Aged|*RNA, Long Noncoding|Gene Regulatory Networks|Gene Ontology|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|RNA, Messenger|*Sepsis|Genes, Regulator" 1 RPS4XP2 29179492 Oncotarget 2017 PMC5687662 10.18632/oncotarget.21634 3 0 0 0 "Humans|*Gliomas|*Prognosis|Primary Brain Tumors|Gene Expression Profiling|Biomarkers, Tumor|Mutation|Gene Expression Profiles" 1 SDC4P 28507442 Onco Targets Ther 2017 PMC5428754 10.2147/OTT.S128058 1 3 0 0 "Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|*Promoter Regions, Genetic|DNA Methylation|Prognosis|Biomarkers, Tumor|Gene Expression Regulation, Neoplastic" 1 U47924.27 28225791 PLoS ONE 2017 PMC5321451 10.1371/journal.pone.0172498 11 12 0 0 "Humans|*RNA, Long Noncoding|Melanoma, Cutaneous Malignant|*Melanoma|Cancer, Skin|*Tumorigenesis|Messenger RNA|Gene Ontology|Oligonucleotide Array Sequence Analysis|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|*Cell Transformation, Neoplastic|MicroRNAs|Gene Regulatory Networks|*Neoplastic Processes|*Nucleotide Motifs" 1 AL356739.1 26902266 Sci Rep 2016 PMC4763273 10.1038/srep21440 10 2 1 0 "Humans|*Uric Acid|*Genome-Wide Association Study|*Diabetes Mellitus, Type 2|*Asian Continental Ancestry Group|ATP Binding Cassette Transporter, Subfamily G, Member 2|Hyperuricemia|Glucose Transport Proteins, Facilitative|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|ATP-Binding Cassette Transporters|Case-Control Studies|Neoplasm Proteins|Risk Factor|SLC2A9 protein, human" 1 BCRP3 27826625 Int. J. Oncol. 2016 10.3892/ijo.2016.3716 44 0 0 0 "Humans|*RNA, Long Noncoding|*Lung Adenocarcinoma|miRNAs|Prognosis|mRNA|Gene Regulatory Networks|Gene Expression Regulation, Neoplastic|Biomarkers, Tumor|Gene Ontology|Lymphatic Metastasis|Kaplan-Meier Estimate|TNM Staging System|Lung Neoplasms" 1 C2CD4C 27349930 FEBS Lett. 2016 PMC5129588 10.1002/1873-3468.12271 0 0 1 11 "Mice|Animals|*Islets of Langerhans|Insulin-Secreting Cells|*Organogenesis|Pancreas|Insulin|Endocrine Cells|Cell Lineage|Homeodomain Proteins|Cell Differentiation|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Transcription Factors|*Neuroendocrine Cells|Mice, Knockout|C2cd4c protein, mouse|Calcium-Binding Proteins" 1 C6orf183 26977737 Am. J. Respir. Crit. Care Med. 2016 PMC5074655 10.1164/rccm.201512-2431OC 31 0 0 0 "Humans|*Hispanic Americans|*Sleep Apnea, Obstructive|Polysomnography|European Continental Ancestry Group|Genome-Wide Association Study|*Phenotype|Cardiovascular Disease|Diabetes Mellitus|Severity of Illness Index" 1 C7orf72 29263810 NPJ Genom Med 2016 PMC5685324 10.1038/npjgenmed.2016.8 6 4 1 0 "*Spondylitis, Ankylosing|*Exome|*Inflammatory Bowel Disease|Genetic Predisposition to Disease|Gene Frequency|*Genetic Background|Spine" 1 C9orf173 26956253 Eur. J. Hum. Genet. 2016 PMC4989203 10.1038/ejhg.2016.14 1 0 0 3 "Humans|*Rubinstein-Taybi Syndrome|Filippi syndrome|*Facies|*Microcephaly|*Intellectual Disability|*Syndactyly|*Growth Disorders|*Mutation|CREB-Binding Protein|Sequencing, Whole Exome|Genetic Association Studies|Phenotype|CREBBP protein, human" 1 CCSER2 27526934 BMC Genomics 2016 PMC4986254 10.1186/s12864-016-2946-1 9 9 1 105 "*Genes, Essential|Real Time PCR|Gene Expression Profiling|High-Throughput Nucleotide Sequencing" 1 FAM98C 27894351 Genome Biol. 2016 PMC5126998 10.1186/s13059-016-1099-5 32 3 0 1 "*Ciliopathies|Ciliary Motility Disorders|Cilia|Polycystic Kidney Diseases|Eye Abnormalities|Retinitis Pigmentosa|Encephalocele|Abnormalities, Multiple|Cerebellum|Retina|Phenotype|Mutation|Pedigree" 1 MIRLET7F1 26847233 Mol Med Rep 2016 10.3892/mmr.2016.4841 4 8 0 0 "Humans|Male|*Lycopene|*Cell Proliferation|*MicroRNAs|*Apoptosis|AKT1 protein, human|Protein Kinase B|*Prostate Cancer|Gene Expression Regulation, Neoplastic|Downregulation|Cell Line, Tumor|Upregulation" 1 MRPS35P3 27768789 Invest. 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Med. 2015 PMC4689169 10.1084/jem.20151093 70 6 4 0 "Humans|*Autoimmunity|CD8-Positive T-Lymphocytes|*Psoriasis|*Melanocyte|HLA-C Antigens|Skin|Autoantigens|Epidermis|Receptors, Antigen, T-Cell, alpha-beta|Histocompatibility Antigens Class I|Lymphocyte Activation|ADAMTSL5 protein, human|ADAMTS Proteins" 1 Q9BQI3 25658109 PLoS Pathog. 2015 PMC4450062 10.1371/journal.ppat.1004618 12 30 2 0 *Trypanosoma cruzi|*eIF-2alpha Kinase|*Haem|*Reactive Oxygen Species|Chagas Disease|EIF-2|*Endosomes|*Cell Differentiation|Phosphorylation|Protozoan Proteins|Cell Proliferation 1 RPL32P31 26158673 PLoS ONE 2015 PMC4497718 10.1371/journal.pone.0132028 0 5 0 0 "Humans|Male|*Prostatic Hyperplasia|*Prostate|Prostate Cancer|Prostate-Specific Antigen|*Complement Factor B|Single Nucleotide Polymorphisms|Genotype|Biopsy|Case-Control Studies|Organ Size|Linear Models|Obesity|SLC12A7 protein, human|Symporters" 1 SCGB2B2 26437309 Gene 2015 10.1016/j.gene.2015.09.070 4 0 0 0 "Animals|Humans|*Old World Monkeys|*Apes|HEK293 Cells|*Promoter Regions, Genetic|Microsatellite Repeats|Evolution, Molecular|Genome|Amino Acid Sequence" 1 SETP7 25663216 Arch. Virol. 2015 10.1007/s00705-015-2344-z 9 0 1 0 "*Bacteriophage|Siphoviridae|Salmonella Phages|Genome, Viral|Nucleotide Sequence|Viral Proteins|Open Reading Frames|Sequence Analysis, DNA|Phylogeny|Synteny|Republic of Korea|Canada" 1 AC000110.1 24995079 Int J Clin Exp Med 2014 PMC4073740 14 0 0 0 "Humans|*RNA, Long Noncoding|*Urinary Bladder|*Carcinoma, Transitional Cell|Gene Expression Profiling|Oligonucleotide Array Sequence Analysis|Urinary Bladder Neoplasms|Gene Expression Regulation, Neoplastic|Gene Regulatory Networks|RNA, Messenger|*Urologic Neoplasms" 1 AC009499.1 25124853 Sci Rep 2014 PMC4133709 10.1038/srep06088 153 10 20 0 "Male|*RNA, Long Noncoding|*Stomach Neoplasms|miRNAs|PTEN protein, human|PTEN Phosphohydrolase|Gene Expression Regulation, Neoplastic|mRNA|Gene Expression Profiling|Cell Transformation, Neoplastic|Cell Line, Tumor|Oncogenesis|Bioinformatic|Head and Neck Squamous Cell Carcinoma|Head and Neck Neoplasms" 1 C10orf105 25380588 J. 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Cell Res. 2010 10.1016/j.yexcr.2010.01.019 12 15 0 67 "Animals|CLU protein, human|*Clusterin|*Neuroblastoma|Binding Protein|Nuclear Proteins|Tumor Suppressor Proteins|Primate|Protein Binding|Cell Line, Tumor|Signal Transduction|Transfection" 1 RPEP1 20500672 Parasite Immunol. 2010 10.1111/j.1365-3024.2010.01208.x 9 0 2 0 "Sheep|Animals|*Haemonchus|*Proteases|Haemonchiasis|*Immunizations|*Vaccination|Antibodies, Helminth|Antigens, Helminth|Sheep Diseases|Helminth Proteins|Parasite Egg Count|Vaccines, Synthetic|Enzyme-Linked Immunosorbent Assay|Metalloendopeptidases|*Anthrax Vaccines|Aspartic Acid Endopeptidases|Recombinant Proteins|Immunoglobulin G|Adjuvants, Immunologic" 1 ANKRD20A1 19796537 Clin. Exp. Rheumatol. 2009 4 2 0 1 "Humans|PTEN-induced putative kinase|Behcet Syndrome|Genetic Susceptibility|Autoantibodies|Inflammation|Case-Control Studies|*Immunologic Tests|Turkey|PTEN protein, human|PTEN Phosphohydrolase" 1 ANKRD20A1 19796537 Clin. Exp. 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Psychiatry 2008 10.1016/j.biopsych.2008.04.035 20 0 2 0 "Humans|*Executive Function|*Schizophrenia|Genetic Predisposition to Disease|Polymorphism, Single Nucleotide|Linkage Disequilibrium|Genetic Linkage|*Attention|Gene Frequency|Genotype|Neuropsychological Tests|Asian Continental Ancestry Group|*Chromosome Structures|MYH9 protein, human|Myosin Heavy Chains|Molecular Motor Proteins|RASD2 protein, human|GTP-Binding Proteins" 1 GGTLC1 18357469 Hum. Genet. 2008 10.1007/s00439-008-0487-7 35 0 5 3 "Humans|Rats|Animals|Glutathionuria|gamma-glutamyltransferase, human|*gamma-Glutamyltransferase|Arabidopsis|Glutathione|Amino Acid Sequence|Base Sequence|Sequence Homology, Nucleic Acid|cDNA|Genomics|Amino Acid Metabolism, Inborn Errors" 1 SETP1 19074657 J. Med. 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Immun. 2001 PMC100077 10.1128/IAI.69.11.6970-6980.2001 23 0 1 0 "Humans|*Helicobacter pylori|*Genomic Islands|*Oligonucleotide Array Sequence Analysis|Helicobacter Infections|Gastric Mucosa|*Epithelial Cell|Gene Expression Regulation|Stomach Neoplasms|Stomach|Bacterial Proteins|Transcription, Genetic|Gene Expression Profiling|Transcription Factors|RNA, Messenger|Cell Line|ADAM10 Protein" 1 O14813 11600883 Nat. Genet. 2001 10.1038/ng744 49 0 1 0 "Humans|Mice|Animals|Congenital Fibrosis of the Extraocular Muscles|Fibrosis Of Extraocular Muscles, Congenital, 2|*Ophthalmoplegia|Fibrosis of Extraocular Muscles, Congenital, 3B|*Fibrosis|Eye Diseases, Hereditary|*Mutations|Blepharoptosis|Homeodomain Proteins|Duane Syndrome|Pedigree|*Homozygote|Ocular Motility Disorders|Oculomotor Muscles|Transcription Factor|Eye Movements|Diabetes Mellitus, Type 2|PHOX2A protein, human" 1 SULT1D1P 11688987 Biochem. Biophys. Res. 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