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.close{display:none}.drawer-toggle:not(.persistent){display:none}}:checked+.drawer:not(.right){left:0}:checked+.drawer.right{right:0}table{border-collapse:separate;border-spacing:0;border:.0625rem solid #c9c9c9;margin:0 auto}table caption{font-size:1.5rem;margin:.5rem}table tr{padding:.5rem}table th,table td{padding:.625rem;border-left:.0625rem solid #c9c9c9;border-top:.0625rem solid #c9c9c9}table td{background:#fafafa}table thead th{border-top:0}table th{background:#e6e6e6}table th:first-child,table td:first-child{border-left:0}@media screen and (max-width: 767px){table:not(.preset){border-collapse:collapse;border:0;width:100%}table:not(.preset) thead,table:not(.preset) th{border:0;height:1px;width:1px;margin:-1px;overflow:hidden;padding:0;position:absolute;clip:rect(0 0 0 0);-webkit-clip-path:inset(100%);clip-path:inset(100%)}table:not(.preset) tr{display:block;border:.0625rem solid #c9c9c9;background:#fafafa;margin-bottom:.625rem}table:not(.preset) td{display:block;border:0;border-bottom:.0625rem solid #c9c9c9;text-align:right}table:not(.preset) td:before{content:attr(data-label);float:left;font-weight:700}table:not(.preset) td:last-child{border-bottom:0}}@media screen and (min-width: 768px){table.horizontal,table.scrollable{display:-webkit-box;-webkit-box-flex:0;-webkit-box-orient:horizontal;-webkit-box-direction:normal;display:-webkit-flex;display:flex;-webkit-flex:0 1 auto;flex:0 1 auto;-webkit-flex-flow:row wrap;flex-flow:row wrap;padding:.5rem}table.horizontal caption,table.scrollable caption{-webkit-box-flex:1;max-width:100%;-webkit-flex:0 0 100%;flex:0 0 100%}table.horizontal thead,table.horizontal tbody,table.scrollable thead,table.scrollable tbody{display:-webkit-box;-webkit-box-flex:0;-webkit-box-orient:horizontal;-webkit-box-direction:normal;display:-webkit-flex;display:flex}table.horizontal thead,table.scrollable thead{z-index:999}table.horizontal tr,table.scrollable tr{display:-webkit-box;display:-webkit-flex;display:flex}table.horizontal thead,table.horizontal tbody{-webkit-flex-flow:row nowrap;flex-flow:row nowrap}table.horizontal tbody{overflow:auto;-webkit-box-pack:justify;-webkit-justify-content:space-between;justify-content:space-between;-webkit-flex:1 0 0;flex:1 0 0}table.horizontal tr{-webkit-box-flex:1;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;flex-direction:column;-webkit-flex:1 0 auto;flex:1 0 auto}table.horizontal th,table.horizontal td{width:100%;border:.0625rem solid #c9c9c9}table.horizontal th:not(:first-child),table.horizontal td:not(:first-child){border-top:0}table.horizontal th{text-align:right}table.horizontal thead tr:first-child{padding-left:0}table.horizontal tbody tr:first-child>td{padding-left:1.25rem}table.scrollable{overflow:auto;max-height:400px;border:0;padding-top:0}table.scrollable thead,table.scrollable tbody{-webkit-box-flex:1;max-width:100%;-webkit-flex-flow:row wrap;flex-flow:row wrap;-webkit-flex:0 0 100%;flex:0 0 100%;border:.0625rem solid #c9c9c9}table.scrollable tbody{border-top:0;margin-top:-0.0625rem}table.scrollable tr{-webkit-box-flex:0;-webkit-box-orient:horizontal;-webkit-box-direction:normal;-webkit-flex-flow:row wrap;flex-flow:row wrap;-webkit-flex:0 0 100%;flex:0 0 100%;padding:0}table.scrollable th,table.scrollable td{-webkit-box-flex:1;-webkit-flex:1 0 0%;flex:1 0 0%;overflow:hidden;text-overflow:ellipsis}table.scrollable thead{position:sticky;top:0}}@media screen and (max-width: 767px){table.horizontal.preset,table.scrollable.preset{display:-webkit-box;-webkit-box-flex:0;-webkit-box-orient:horizontal;-webkit-box-direction:normal;display:-webkit-flex;display:flex;-webkit-flex:0 1 auto;flex:0 1 auto;-webkit-flex-flow:row wrap;flex-flow:row wrap;padding:.5rem}table.horizontal.preset caption,table.scrollable.preset caption{-webkit-box-flex:1;max-width:100%;-webkit-flex:0 0 100%;flex:0 0 100%}table.horizontal.preset thead,table.horizontal.preset tbody,table.scrollable.preset thead,table.scrollable.preset tbody{display:-webkit-box;-webkit-box-flex:0;-webkit-box-orient:horizontal;-webkit-box-direction:normal;display:-webkit-flex;display:flex}table.horizontal.preset thead,table.scrollable.preset thead{z-index:999}table.horizontal.preset tr,table.scrollable.preset tr{display:-webkit-box;display:-webkit-flex;display:flex}table.horizontal.preset thead,table.horizontal.preset tbody{-webkit-flex-flow:row nowrap;flex-flow:row nowrap}table.horizontal.preset tbody{overflow:auto;-webkit-box-pack:justify;-webkit-justify-content:space-between;justify-content:space-between;-webkit-flex:1 0 0;flex:1 0 0}table.horizontal.preset tr{-webkit-box-flex:1;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;flex-direction:column;-webkit-flex:1 0 auto;flex:1 0 auto}table.horizontal.preset th,table.horizontal.preset td{width:100%;border:.0625rem solid #c9c9c9}table.horizontal.preset th:not(:first-child),table.horizontal.preset td:not(:first-child){border-top:0}table.horizontal.preset th{text-align:right}table.horizontal.preset thead tr:first-child{padding-left:0}table.horizontal.preset tbody tr:first-child>td{padding-left:1.25rem}table.scrollable.preset{overflow:auto;max-height:400px;border:0;padding-top:0}table.scrollable.preset thead,table.scrollable.preset tbody{-webkit-box-flex:1;max-width:100%;-webkit-flex-flow:row wrap;flex-flow:row wrap;-webkit-flex:0 0 100%;flex:0 0 100%;border:.0625rem solid #c9c9c9}table.scrollable.preset tbody{border-top:0;margin-top:-0.0625rem}table.scrollable.preset tr{-webkit-box-flex:0;-webkit-box-orient:horizontal;-webkit-box-direction:normal;-webkit-flex-flow:row wrap;flex-flow:row wrap;-webkit-flex:0 0 100%;flex:0 0 100%;padding:0}table.scrollable.preset th,table.scrollable.preset td{-webkit-box-flex:1;-webkit-flex:1 0 0%;flex:1 0 0%;overflow:hidden;text-overflow:ellipsis}table.scrollable.preset thead{position:sticky;top:0}}table.striped tr:nth-of-type(2n)>td{background:#e5e5e5}@media screen and (max-width: 767px){table.striped:not(.preset) tr:nth-of-type(2n){background:#e5e5e5}}.card{display:-webkit-box;-webkit-box-orient:vertical;-webkit-box-pack:justify;-webkit-box-align:center;display:-webkit-flex;display:flex;-webkit-flex-direction:column;flex-direction:column;-webkit-justify-content:space-between;justify-content:space-between;-webkit-align-self:center;align-self:center;position:relative;width:100%;background:#fafafa;border:.0625rem solid #acacac;margin:.5rem;overflow:hidden}.card>.section{box-sizing:border-box;margin:0;border:0;border-radius:0;border-bottom:.0625rem solid #c9c9c9;padding:.5rem;width:100%}.card>.section.media{height:200px;padding:0;-o-object-fit:cover;object-fit:cover}.card>.section:last-child{border-bottom:0}@media screen and (min-width: 320px){.card{max-width:320px}}@media screen and (min-width: 480px){.card.large{max-width:480px}}@media screen and (min-width: 240px){.card.small{max-width:240px}}.card.fluid{max-width:100%;width:auto}.card.warning{background:#ffca28;border:.0625rem solid #e8b825}.card.warning>.section{border-bottom:.0625rem solid #e8b825}.card.warning>.section:last-child{border-bottom:0}.card.error{background:#b71c1c;color:#fafafa;border:.0625rem solid #a71a1a}.card.error>.section{border-bottom:.0625rem solid #a71a1a}.card.error>.section:last-child{border-bottom:0}.card>.section.dark{background:#e0e0e0}.card>.section.darker{background:#bdbdbd}.card>.section.double-padded{padding:.75rem}.tabs{width:100%;opacity:1;display:-webkit-box;-webkit-box-pack:justify;display:-webkit-flex;display:flex;-webkit-justify-content:space-between;justify-content:space-between;-webkit-flex-wrap:wrap;flex-wrap:wrap}.tabs>label{-webkit-box-flex:1;-webkit-flex-grow:1;flex-grow:1;-webkit-order:1;order:1;display:inline-block;height:1.5rem;cursor:pointer;transition:background 0.3s;background:#e6e6e6;border:.0625rem solid #bdbdbd;padding:.75rem}.tabs>label:hover,.tabs>label:focus{background:rgba(230,230,230,0.8)}.tabs>[type="radio"],.tabs>[type="checkbox"]{display:none;visibility:hidden}.tabs>label+div{-webkit-flex-basis:auto;flex-basis:auto;-webkit-order:2;order:2;height:1px;width:1px;margin:-1px;overflow:hidden;position:absolute;clip:rect(0 0 0 0);-webkit-clip-path:inset(100%);clip-path:inset(100%);-webkit-transform:scaleY(0);transform:scaleY(0);-webkit-transform-origin:top;transform-origin:top;transition:-webkit-transform 0.3s,
transform 0.3s}.tabs>label:not(:first-of-type){border-left:0}.tabs>:checked+label{background:#eee;border-bottom-color:#0277bd}.tabs>:checked+label:hover,.tabs>:checked+label:focus{background:rgba(238,238,238,0.8)}.tabs>:checked+label+div{box-sizing:border-box;position:relative;height:400px;width:100%;overflow:auto;margin:0;-webkit-transform:scaleY(1);transform:scaleY(1);background:#fafafa;border:.0625rem solid #bdbdbd;border-top:0;padding:.5rem;clip:auto;-webkit-clip-path:inset(0%);clip-path:inset(0%)}.tabs.stacked{-webkit-box-orient:vertical;-webkit-flex-direction:column;flex-direction:column}.tabs.stacked>label{-webkit-order:initial;order:initial}.tabs.stacked>:checked+label{border:.0625rem solid #bdbdbd}.tabs.stacked>label+div{-webkit-order:initial;order:initial;-webkit-transform-origin:top;transform-origin:top}.tabs.stacked>label:not(:first-of-type){border:.0625rem solid #bdbdbd;border-top:0}.tabs.stacked>:checked+label+div{height:auto}@media screen and (max-width: 767px){.tabs{-webkit-box-orient:vertical;-webkit-flex-direction:column;flex-direction:column}.tabs>label{-webkit-order:initial;order:initial}.tabs>:checked+label{border:.0625rem solid #bdbdbd}.tabs>label+div{-webkit-order:initial;order:initial}.tabs>label:not(:first-of-type){border:.0625rem solid #bdbdbd;border-top:0}}mark{background:#0277bd;color:#fafafa;font-size:.9375em;line-height:1em;border-radius:.125rem;padding:0.125em 0.25em}mark.inline-block{display:inline-block}.toast{position:fixed;background:#424242;bottom:1.5rem;left:50%;transform:translate(-50%, -50%);color:#fafafa;border-radius:2rem;padding:0.75rem 1.5rem;z-index:1111}.tooltip{position:relative;display:inline-block}.tooltip:before,.tooltip:after{position:absolute;opacity:0;clip:rect(0 0 0 0);-webkit-clip-path:inset(100%);clip-path:inset(100%);transition:all 0.3s;z-index:1010;left:50%}.tooltip:not(.bottom):before,.tooltip:not(.bottom):after{bottom:75%}.tooltip.bottom:before,.tooltip.bottom:after{top:75%}.tooltip:hover:before,.tooltip:hover:after,.tooltip:focus:before,.tooltip:focus:after{opacity:1;clip:auto;-webkit-clip-path:inset(0%);clip-path:inset(0%)}.tooltip:before{content:'';background:transparent;border:.5rem solid transparent;left:50%;left:calc(50% - .5rem)}.tooltip:not(.bottom):before{border-top-color:#212121}.tooltip.bottom:before{border-bottom-color:#212121}.tooltip:after{content:attr(aria-label);background:#212121;border-radius:.125rem;color:#fafafa;padding:.5rem;white-space:nowrap;-webkit-transform:translateX(-50%);transform:translateX(-50%)}.tooltip:not(.bottom):after{margin-bottom:1rem}.tooltip.bottom:after{margin-top:1rem}.modal{position:fixed;top:0;left:0;display:none;width:100vw;height:100vh;background:rgba(0,0,0,0.45)}.modal .card{margin:0 auto;max-height:50vh;overflow:auto}.modal .card .close{position:absolute;top:.75rem;right:.25rem;padding:0}:checked+.modal{display:-webkit-box;-webkit-box-flex:0;display:-webkit-flex;display:flex;-webkit-flex:0 1 auto;flex:0 1 auto;z-index:1200}:checked+.modal .card .close{z-index:1211}mark.secondary{background:#e53935}mark.tertiary{background:#689f38}mark.tag{border-radius:200px;padding:0.25em 0.5em}mark.inline-block{font-size:1em;line-height:1.375em;padding:.375em}.toast.small{border-radius:1.5rem;padding:0.5rem 1rem}.toast.large{border-radius:3rem;padding:1.125rem 2.25rem}progress{display:block;vertical-align:baseline;-webkit-appearance:none;-moz-appearance:none;appearance:none;height:.625rem;width:90%;width:calc(100% - 1rem);margin:.5rem .5rem;border:0;border-radius:.125rem;background:#e0e0e0;color:#0277bd}progress::-webkit-progress-value{background:#0277bd;border-top-left-radius:.125rem;border-bottom-left-radius:.125rem}progress::-webkit-progress-bar{background:#e0e0e0}progress::-moz-progress-bar{background:#0277bd;border-top-left-radius:.125rem;border-bottom-left-radius:.125rem}progress[value="1000"]::-webkit-progress-value{border-radius:.125rem}progress[value="1000"]::-moz-progress-bar{border-radius:.125rem}@-webkit-keyframes spinner-donut-anim{0%{-webkit-transform:rotate(0deg)}100%{-webkit-transform:rotate(360deg)}}@keyframes spinner-donut-anim{0%{transform:rotate(0deg)}100%{transform:rotate(360deg)}}.spinner-donut{display:inline-block;border:.25rem solid #e3f2fd;border-left:.25rem solid #1565c0;border-radius:50%;width:1.25rem;height:1.25rem;-webkit-animation:spinner-donut-anim 1.2s linear infinite;animation:spinner-donut-anim 1.2s linear infinite}progress.inline{display:inline-block;vertical-align:middle;width:60%}progress.secondary{color:#e53935}progress.secondary::-webkit-progress-value{background:#e53935}progress.secondary::-moz-progress-bar{background:#e53935}progress.tertiary{color:#689f38}progress.tertiary::-webkit-progress-value{background:#689f38}progress.tertiary::-moz-progress-bar{background:#689f38}.spinner-donut.secondary{border:.25rem solid #ffebee;border-left:.25rem solid #c62828}.spinner-donut.tertiary{border:.25rem solid #e8f5e9;border-left:.25rem solid #2e7d32}.spinner-donut.large{border-width:.375rem;width:2rem;height:2rem}.hidden{display:none !important}.visually-hidden{position:absolute !important;width:1px !important;height:1px !important;margin:-1px !important;border:0 !important;padding:0 !important;clip:rect(0 0 0 0) !important;-webkit-clip-path:inset(100%) !important;clip-path:inset(100%) !important;overflow:hidden !important}ul.breadcrumbs{display:-webkit-box;display:-webkit-flex;display:flex;list-style:none;margin:.5rem;padding:0}ul.breadcrumbs li{-webkit-box-flex:1;max-width:100%;-webkit-flex-grow:1;flex-grow:1;-webkit-flex-basis:0;flex-basis:0;position:relative;text-align:center;background:#e6e6e6;height:2rem;line-height:2rem;margin-right:1.125rem}ul.breadcrumbs li:before,ul.breadcrumbs li:after{content:"";position:absolute;top:0;width:0;height:0;border:0 solid #e6e6e6;border-width:1rem 1rem}ul.breadcrumbs li:before{left:-1rem;border-left-color:transparent}ul.breadcrumbs li:after{left:100%;border-color:transparent;border-left-color:#e6e6e6}ul.breadcrumbs li:first-child:before{border:0}ul.breadcrumbs li:last-child{margin-right:0}ul.breadcrumbs li:last-child:after{border:0}.close{display:inline-block;width:1.5rem;font-family:sans-serif;font-size:1.5rem;line-height:1;font-weight:700;border-radius:2rem;background:rgba(230,230,230,0);vertical-align:top;cursor:pointer;transition:background 0.3s}.close:hover,.close:focus{background:#e6e6e6}.close:before{content:"\00D7";display:block;text-align:center}.bordered{border:1px solid rgba(0,0,0,0.25) !important}.rounded{border-radius:.125rem !important}.circular{border-radius:50% !important}.responsive-margin{margin:.25rem !important}@media screen and (min-width: 768px){.responsive-margin{margin:.375rem !important}}@media screen and (min-width: 1280px){.responsive-margin{margin:.5rem !important}}.responsive-padding{padding:0.125rem 0.25rem !important}@media screen and (min-width: 768px){.responsive-padding{padding:0.25rem 0.375rem !important}}@media screen and (min-width: 1280px){.responsive-padding{padding:0.375rem 0.5rem !important}}.shadowed{box-shadow:0 .25rem .25rem 0 rgba(0,0,0,0.125),0 .125rem .125rem -.125rem rgba(0,0,0,0.25) !important}@media screen and (max-width: 767px){.hidden-sm{display:none !important}}@media screen and (min-width: 768px) and (max-width: 1279px){.hidden-md{display:none !important}}@media screen and (min-width: 1280px){.hidden-lg{display:none !important}}@media screen and (max-width: 767px){.visually-hidden-sm{position:absolute !important;width:1px !important;height:1px !important;margin:-1px !important;border:0 !important;padding:0 !important;clip:rect(0 0 0 0) !important;-webkit-clip-path:inset(100%) !important;clip-path:inset(100%) !important;overflow:hidden !important}}@media screen and (min-width: 768px) and (max-width: 1279px){.visually-hidden-md{position:absolute !important;width:1px !important;height:1px !important;margin:-1px !important;border:0 !important;padding:0 !important;clip:rect(0 0 0 0) !important;-webkit-clip-path:inset(100%) !important;clip-path:inset(100%) !important;overflow:hidden !important}}@media screen and (min-width: 1280px){.visually-hidden-lg{position:absolute !important;width:1px !important;height:1px !important;margin:-1px !important;border:0 !important;padding:0 !important;clip:rect(0 0 0 0) !important;-webkit-clip-path:inset(100%) !important;clip-path:inset(100%) !important;overflow:hidden !important}}
</style>
<style>
/* ^^/styles/slim-select.css$$ */
.ss-main {
position: relative;
display: inline-block;
user-select: none;
color: #666;
width: 100%
}
.ss-main .ss-single-selected {
display: flex;
cursor: pointer;
width: 100%;
height: 30px;
padding: 6px;
border: 1px solid #dcdee2;
border-radius: 4px;
background-color: #fff;
outline: 0;
box-sizing: border-box;
transition: background-color .3s
}
.ss-main .ss-single-selected.ss-disabled {
background-color: #dcdee2;
cursor: not-allowed
}
.ss-main .ss-single-selected.ss-open-above {
border-top-left-radius: 0;
border-top-right-radius: 0
}
.ss-main .ss-single-selected.ss-open-below {
border-bottom-left-radius: 0;
border-bottom-right-radius: 0
}
.ss-main .ss-single-selected .placeholder {
display: flex;
align-items: center;
flex: 1 1 100%;
text-align: left;
width: calc(100% - 30px);
line-height: 1em
}
.ss-main .ss-single-selected .placeholder * {
display: flex;
align-items: center;
overflow: hidden;
text-overflow: ellipsis;
white-space: nowrap;
width: 100%
}
.ss-main .ss-single-selected .placeholder .ss-disabled {
cursor: pointer;
color: #dcdee2
}
.ss-main .ss-single-selected .ss-arrow {
display: flex;
align-items: center;
justify-content: flex-end;
flex: 0 1 auto;
margin: -1px 4px 0 5px
}
.ss-main .ss-single-selected .ss-arrow span {
border: solid #666;
border-width: 0 2px 2px 0;
display: inline-block;
padding: 3px;
transition: transform .2s, margin .2s
}
.ss-main .ss-single-selected .ss-arrow span.arrow-up {
transform: rotate(-135deg);
margin: 3px 0 0
}
.ss-main .ss-single-selected .ss-arrow span.arrow-down {
transform: rotate(45deg);
margin: -3px 0 0
}
.ss-main .ss-multi-selected {
display: flex;
flex-direction: row;
cursor: pointer;
min-height: 30px;
width: 100%;
padding: 0 0 0 3px;
border: 1px solid #dcdee2;
border-radius: 4px;
background-color: #fff;
outline: 0;
box-sizing: border-box;
transition: background-color .3s
}
.ss-main .ss-multi-selected.ss-disabled {
background-color: #dcdee2;
cursor: not-allowed
}
.ss-main .ss-multi-selected.ss-disabled .ss-values .ss-disabled {
color: #666
}
.ss-main .ss-multi-selected.ss-disabled .ss-values .ss-value .ss-value-delete {
cursor: not-allowed
}
.ss-main .ss-multi-selected.ss-open-above {
border-top-left-radius: 0;
border-top-right-radius: 0
}
.ss-main .ss-multi-selected.ss-open-below {
border-bottom-left-radius: 0;
border-bottom-right-radius: 0
}
.ss-main .ss-multi-selected .ss-values {
display: flex;
flex-wrap: wrap;
justify-content: flex-start;
flex: 1 1 100%;
width: calc(100% - 30px)
}
.ss-main .ss-multi-selected .ss-values .ss-disabled {
display: flex;
padding: 4px 5px;
margin: 2px 0;
line-height: 1em;
align-items: center;
width: 100%;
color: #dcdee2;
overflow: hidden;
text-overflow: ellipsis;
white-space: nowrap
}
@keyframes a {
0% {
transform: scale(0);
opacity: 0
}
to {
transform: scale(1);
opacity: 1
}
}
@keyframes b {
0% {
transform: scale(1);
opacity: 1
}
to {
transform: scale(0);
opacity: 0
}
}
.ss-main .ss-multi-selected .ss-values .ss-value {
display: flex;
user-select: none;
align-items: center;
font-size: 12px;
padding: 3px 5px;
margin: 3px 5px 3px 0;
color: #fff;
background-color: #5897fb;
border-radius: 4px;
animation-name: a;
animation-duration: .2s;
animation-timing-function: ease-out;
animation-fill-mode: both
}
.ss-main .ss-multi-selected .ss-values .ss-value.ss-out {
animation-name: b;
animation-duration: .2s;
animation-timing-function: ease-out
}
.ss-main .ss-multi-selected .ss-values .ss-value .ss-value-delete {
margin: 0 0 0 5px;
cursor: pointer
}
.ss-main .ss-multi-selected .ss-add {
display: flex;
flex: 0 1 3px;
margin: 9px 12px 0 5px
}
.ss-main .ss-multi-selected .ss-add .ss-plus {
display: flex;
justify-content: center;
align-items: center;
background: #666;
position: relative;
height: 10px;
width: 2px;
transition: transform .2s
}
.ss-main .ss-multi-selected .ss-add .ss-plus:after {
background: #666;
content: "";
position: absolute;
height: 2px;
width: 10px;
left: -4px;
top: 4px
}
.ss-main .ss-multi-selected .ss-add .ss-plus.ss-cross {
transform: rotate(45deg)
}
.ss-main .ss-content {
position: absolute;
width: 100%;
margin: -1px 0 0;
box-sizing: border-box;
border: 1px solid #dcdee2;
z-index: 1;
background-color: #fff;
transform-origin: center top;
transition: transform .2s, opacity .2s;
opacity: 0;
transform: scaleY(0)
}
.ss-main .ss-content.ss-open {
display: block;
opacity: 1;
transform: scaleY(1)
}
.ss-main .ss-content .ss-search {
padding: 8px 10px
}
.ss-main .ss-content .ss-search input {
display: block;
font-size: inherit;
width: 100%;
height: 30px;
padding: 5px 10px;
border: 1px solid #dcdee2;
border-radius: 4px;
background-color: #fff;
outline: 0;
box-sizing: border-box
}
.ss-main .ss-content .ss-search input::placeholder {
color: #b3b3b3
}
.ss-main .ss-content .ss-search input:focus {
box-shadow: 0 0 5px #5897fb
}
.ss-main .ss-content .ss-list {
max-height: 200px;
overflow-x: hidden;
overflow-y: auto;
text-align: left
}
.ss-main .ss-content .ss-list .ss-optgroup .ss-optgroup-label {
padding: 6px 10px;
font-weight: 700
}
.ss-main .ss-content .ss-list .ss-optgroup .ss-option {
padding: 6px 6px 6px 25px
}
.ss-main .ss-content .ss-list .ss-option {
padding: 6px 10px;
cursor: pointer;
user-select: none
}
.ss-main .ss-content .ss-list .ss-option * {
display: inline-block;
vertical-align: middle
}
.ss-main .ss-content .ss-list .ss-option.ss-highlighted,
.ss-main .ss-content .ss-list .ss-option:hover {
color: #fff;
background-color: #5897fb
}
.ss-main .ss-content .ss-list .ss-option.ss-disabled {
cursor: default;
color: #dcdee2;
background-color: #fff
}
.ss-main .ss-content .ss-list .ss-option.ss-hide {
display: none
}
</style>
<style>
/* ^^/styles/main.css$$ */
.tab-content {
height: 90vh !important
}
.ss-multi-selected {
max-height: 100px;
overflow-y: auto;
}
.container>.row {
margin: 0px !important
}
.card {
max-width: 98% !important;
overflow: auto;
}
</style>
</head>
<body>
<div style="margin-top:2vh; margin-left: 2vw; width: 96vw; height: 96vh">
<div class="tabs">
<input type="radio" name="tab-group" id="summary" checked aria-hidden="true">
<label for="summary" aria-hidden="true">Summary</label>
<div id="summary-tab" class="tab-content">
<div class="container">
<div class="row" style="padding-left: 5%; padding-right: 5%; width: 100%; padding-top: 20px">
<div class="col-sm-12 col-md-12 col-lg-12" style="border: 1px solid #aeaeae">
<div class="card" style="border: 0px">
<div class="section">
<h3>Basic Info</h3>
<div class="row" style="width : 90%; padding-left: 5%">
<div class="col-sm-12 col-md-12 col-lg-12">
<h4 style="position: relative; font-weight: bold; left: -20px">Genome info</h4>
</div>
<div class="col-sm-6 col-md-6 col-lg-3" style="padding-bottom: 20px"><b>Fasta file: </b><span id='name'>name</span></div>
<div class="col-sm-6 col-md-6 col-lg-3" style="padding-bottom: 20px"><b>Total size: </b><span id='genomeSize'>genomeSize</span></div>
<div class="col-sm-6 col-md-6 col-lg-3" style="padding-bottom: 20px"><b>GC %</b>: </b><span id='GC'>GC</span></div>
<div class="col-sm-6 col-md-6 col-lg-3" style="padding-bottom: 20px"><b>No.of sequences: </b><span id='numSeq'>numSeq</span></div>
</div>
<div class="row" style="width : 90%; padding-left: 5%">
<div class="col-sm-12 col-md-12 col-lg-12">
<h4 style="position: relative; font-weight: bold; left: -20px">Repeat info</h4>
</div>
<div class="col-sm-6 col-md-6 col-lg-4" style="padding-bottom: 20px"><b>Repeat occurrences: </b><span id='totalRepFreq'>totalRepFreq</span></div>
<div class="col-sm-6 col-md-6 col-lg-4" style="padding-bottom: 20px"><b>Total repeat bases: </b><span id='totalRepBases'>totalRepBases</span></div>
<div class="col-sm-6 col-md-6 col-lg-4" style="padding-bottom: 20px"><b>Percent genome covered: </b><span id='percentGenomeCovered'>percentGenomeCovered</span></div>
<div class="col-sm-6 col-md-6 col-lg-4" style="padding-bottom: 20px"><b>Repeat classes: </b><span id='numRepClass'>numRepClass</span>/501</div>
<div class="col-sm-6 col-md-6 col-lg-4" style="padding-bottom: 20px"><b>Repeat occurrences per MB: </b><span id='repDensityByFreq'>repDensityByFreq</span></div>
<div class="col-sm-6 col-md-6 col-lg-4" style="padding-bottom: 20px"><b>Repeat bases per MB: </b><span id='repDensityByBases'>repDensityByBases</span></div>
</div>
</div>
</div>
</div>
</div>
<div class="row" style="padding-left: 5%; padding-right: 5%; width: 100%; padding-top: 20px">
<div class="col-sm-12 col-md-12 col-lg-6" style="border: 1px solid #aeaeae; width: 90%">
<div class="card" style="border: 0px">
<div class="section">
<h3 style="text-align: center; padding: 10px">Most repeat unit occurrences</h3>
<table id="most-repeat-units-table" class="scrollable">
<thead>
<tr>
<th title="Sequence id">Sequence id</th>
<th title="Start">Start</th>
<th title="End">End</th>
<th title="Repeat class">Repeat class</th>
<th title="Length">Length</th>
<th title="Strand">Strand</th>
<th title="Repeat units">Repeat units</th>
<th title="Actual repeat">Actual repeat</th>
</tr>
</thead>
<tbody>
</tbody>
</table>
</div>
</div>
</div>
<div class="col-sm-12 col-md-12 col-lg-6" style="border: 1px solid #aeaeae">
<div class="card" style="border: 0px">
<div class="section">
<h3 style="text-align: center; padding: 10px">Longest repeat occurrences</h3>
<table id="longest-repeats-table" class="scrollable">
<thead>
<tr>
<th title="Sequence id">Sequence id</th>
<th title="Start">Start</th>
<th title="End">End</th>
<th title="Repeat class">Repeat class</th>
<th title="Length">Length</th>
<th title="Strand">Strand</th>
<th title="Repeat units">Repeat units</th>
<th title="Actual repeat">Actual repeat</th>
</tr>
</thead>
<tbody>
</tbody>
</table>
</div>
</div>
</div>
</div>
</div>
</div>
<!---- Repeat Frequency - Bar Plot Tab-->
<input type="radio" name="tab-group" id="bar-plot" aria-hidden="true" , onchange="placeholderBarPlot()">
<label for="bar-plot" aria-hidden="true" class="plotTabLabel">Repeat Frequency</label>
<div id="bar-plotarea" class="tab-content">
<div class="container">
<div class="row" style="width: 100%; padding-top: 20px">
<div class="col-sm-12 col-md-6 col-lg-6">
<form style="margin: 0px !important; padding: 5px !important">
<fieldset>
<legend style="font-size: 1em">Sort Selection</legend>
<div class="input-group">
Show
<input id="bar-num" type="number" min="1" max="501" value="10" name="repeats" style="padding: 3px !important; width: 100px"></input>
<select id="bar-select" style="padding-top: 3px; padding-bottom: 3px">
<option value="1" selected>most</option>
<option value="0">least</option>
</select> Repeats
</div>
</fieldset>
</form>
</div>
<div class="col-sm-12 col-md-6 col-lg-6">
<form style="margin: 0px !important; padding: 5px !important">
<fieldset>
<legend style="font-size: 1em">Repeat Selection</legend>
<div class="col-sm-6 col-md-6 col-lg-6 input-group">
<select id="bar-repeats-sel" style="width: 20vw !important" multiple></select>
</div>
<div class=" col-sm-6 col-md-6 col-lg-6 input-group" style="margin-left: 20px">
<div>
<input type="radio" id="bar-sort-radio" value=1 name="bar-sort">
<label for="bar-sort-radio">Sort by frequency</label>
</div>
<div>
<input type="radio" id="bar-unsort-radio" value=0 name="bar-sort" checked>
<label for="bar-unsort-radio">Sort alphabetically</label>
</div>
</div>
</fieldset>
</form>
</div>
</div>
<div class="row" id="bar-plot-svg" style="padding-top: 20px; width: 100%; height: 72vh">
</div>
</div>
</div>
<!---- Repeat Dsitribution - Pie Plot Tab-->
<input type="radio" name="tab-group" id="pie-plot" aria-hidden="true">
<label for="pie-plot" aria-hidden="true" class="plotTabLabel">Repeat Distribution</label>
<div id="pie-plotarea" class="tab-content">
<div class="container">
<div class="row" style="width: 100%; padding-top: 20px">
<div class="col-sm-6 col-md-3 col-lg-3">
<form style="margin: 0px !important; padding: 5px !important">
<fieldset>
<legend style="font-size: 1em">Data type</legend>
<div class="input-group">
<div>
<input type="radio" id="freq-radio" value="Frequency" name="data-type" checked>
<label for="freq-radio">Frequency</label>
</div>
<div>
<input type="radio" id="bases-radio" value="Bases" name="data-type">
<label for="bases-radio">Bases covered</label>
</div>
</div>
</fieldset>
</form>
</div>
<div class="col-sm-6 col-md-3 col-lg-3">
<form style="margin: 0px !important; padding: 5px !important">
<fieldset>
<legend style="font-size: 1em">Group by length</legend>
<div class="input-group">
<div>
<input type="radio" id="lengroup-on" value="1" name="len-group" checked>
<label for="lengroup-on">On</label>
</div>
<div>
<input type="radio" id="lengroup-off" value="0" name="len-group">
<label for="lengroup-off">Off</label>
</div>
</div>
</fieldset>
</form>
</div>
<div class="col-sm-12 col-md-6 col-lg-6">
<form style="margin: 0px !important; padding: 5px !important; padding-bottom: 14px !important">
<fieldset>
<legend style="font-size: 1em">Repeat Selection</legend>
<div class="input-group">
<select id="pie-repeats-sel" style="width: 30vw !important" multiple></select>
</div>
</fieldset>
</form>
</div>
</div>
<div class="row" id="pie-plot-svg" style="padding-top: 20px; width: 100%; height: 72vh">
</div>
</div>
</div>
<!---- Sequence length vs frequency - Line Plot Tab-->
<input type="radio" name="tab-group" id="line-plot" aria-hidden="true">
<label for="line-plot" aria-hidden="true" class="plotTabLabel">Sequence Length vs Frequency</label>
<div id="line-plotarea" class="tab-content">
<div class="container">
<div class="row" style="width: 100%; padding-top: 20px">
<div class="col-sm-12 col-md-6 col-lg-6">
<form style="margin: 0px !important; padding: 5px !important; padding-bottom: 14px !important">
<fieldset>
<legend style="font-size: 1em">Range</legend>
<div class="row">
<div class="col-sm-4 col-md-4 col-lg-4">
<b>X-axis: </b>
<select id="line-select" style="padding-top: 3px; padding-bottom: 3px">
<option value="1" selected>Repeat length</option>
<option value="0">Repeat units</option>
</select>
</div>
<div class="col-sm-4 col-md-4 col-lg-4">
<label for="min-linex">Min :</label>
<input id="min-linex" type="number" value="12" min="0" style="padding: 3px !important; width: 60%"></input>
</div>
<div class="col-sm-4 col-md-4 col-lg-4">
<label for="max-linex">Max:</label>
<input id="max-linex" type="number" value="12" min="12" style="padding: 3px !important; width: 60%"></input>
</div>
</div>
</fieldset>
</form>
</div>
<div class="col-sm-12 col-md-6 col-lg-6">
<form style="margin: 0px !important; padding: 5px !important; padding-bottom: 14px !important">
<fieldset>
<legend style="font-size: 1em">Repeat Selection</legend>
<div class="input-group">
<select id="line-repeats-sel" style="width: 30vw !important" multiple></select>
</div>
</fieldset>
</form>
</div>
</div>
<div class="row" id="line-plot-svg" style="padding-top: 20px; width: 100%; height: 72vh">
</div>
</div>
</div>
</div>
</div>
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a.color,c.dashStyle||b.dashStyle])});u(d,function(f,d){var e=f[0],h=a[e];h?(h.endX=c.xMap,h.animate({d:c})):c.length&&(a[e]=a.chart.renderer.path(c).addClass(f[1]).attr({zIndex:1}).add(a.group),h={stroke:f[2],"stroke-width":b.lineWidth,fill:a.fillGraph&&a.color||"none"},f[3]?h.dashstyle=f[3]:"square"!==b.linecap&&(h["stroke-linecap"]=h["stroke-linejoin"]="round"),h=a[e].attr(h).shadow(2>d&&b.shadow));h&&(h.startX=c.xMap,h.isArea=c.isArea)})},applyZones:function(){var a=this,b=this.chart,c=b.renderer,
d=this.zones,f,e,h=this.clips||[],l,g=this.graph,r=this.area,n=Math.max(b.chartWidth,b.chartHeight),k=this[(this.zoneAxis||"y")+"Axis"],m,q,w=b.inverted,z,y,B,v,D=!1;d.length&&(g||r)&&k&&void 0!==k.min&&(q=k.reversed,z=k.horiz,g&&g.hide(),r&&r.hide(),m=k.getExtremes(),u(d,function(d,p){f=q?z?b.plotWidth:0:z?0:k.toPixels(m.min);f=Math.min(Math.max(H(e,f),0),n);e=Math.min(Math.max(Math.round(k.toPixels(H(d.value,m.max),!0)),0),n);D&&(f=e=k.toPixels(m.max));y=Math.abs(f-e);B=Math.min(f,e);v=Math.max(f,
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c=this.group,d=this.xAxis,f=this.yAxis;c&&(a.inverted&&c.attr({width:a.plotWidth,height:a.plotHeight}),c.animate({translateX:H(d&&d.left,a.plotLeft),translateY:H(f&&f.top,a.plotTop)}));this.translate();this.render();b&&delete this.kdTree},kdAxisArray:["clientX","plotY"],searchPoint:function(a,b){var c=this.xAxis,d=this.yAxis,f=this.chart.inverted;return this.searchKDTree({clientX:f?c.len-a.chartY+c.pos:a.chartX-c.pos,plotY:f?d.len-a.chartX+d.pos:a.chartY-d.pos},b)},buildKDTree:function(){function a(c,
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F=a.correctFloat,m=a.defined,g=a.destroyObjectProperties,k=a.each,q=a.format,v=a.objectEach,u=a.pick;a=a.Series;C.prototype={destroy:function(){g(this,this.axis)},render:function(a){var e=this.options,h=e.format,h=h?q(h,this):e.formatter.call(this);this.label?this.label.attr({text:h,visibility:"hidden"}):this.label=this.axis.chart.renderer.text(h,null,null,e.useHTML).css(e.style).attr({align:this.textAlign,rotation:e.rotation,visibility:"hidden"}).add(a)},setOffset:function(a,e){var h=this.axis,d=
h.chart,c=d.inverted,g=h.reversed,g=this.isNegative&&!g||!this.isNegative&&g,b=h.translate(h.usePercentage?100:this.total,0,0,0,1),h=h.translate(0),h=Math.abs(b-h);a=d.xAxis[0].translate(this.x)+a;var k=d.plotHeight,c={x:c?g?b:b-h:a,y:c?k-a-e:g?k-b-h:k-b,width:c?h:e,height:c?e:h};if(e=this.label)e.align(this.alignOptions,null,c),c=e.alignAttr,e[!1===this.options.crop||d.isInsidePlot(c.x,c.y)?"show":"hide"](!0)}};G.prototype.getStacks=function(){var a=this;k(a.yAxis,function(a){a.stacks&&a.hasVisibleSeries&&
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function(){var a=this.chart,e=a.renderer,g=this.stacks,d=this.stackTotalGroup;d||(this.stackTotalGroup=d=e.g("stack-labels").attr({visibility:"visible",zIndex:6}).add());d.translate(a.plotLeft,a.plotTop);v(g,function(a){v(a,function(a){a.render(d)})})};A.prototype.resetStacks=function(){var a=this,e=a.stacks;a.isXAxis||v(e,function(e){v(e,function(d,c){d.touched<a.stacksTouched?(d.destroy(),delete e[c]):(d.total=null,d.cum=null)})})};A.prototype.cleanStacks=function(){var a;this.isXAxis||(this.oldStacks&&
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d){var e,h=this;a&&(c=b(c,!0),u(h,"addSeries",{options:a},function(){e=h.initSeries(a);h.isDirtyLegend=!0;h.linkSeries();c&&h.redraw(d)}));return e},addAxis:function(a,d,e,h){var g=d?"xAxis":"yAxis",l=this.options;a=c(a,{index:this[g].length,isX:d});new G(this,a);l[g]=B(l[g]||{});l[g].push(a);b(e,!0)&&this.redraw(h)},showLoading:function(a){var b=this,c=b.options,d=b.loadingDiv,e=c.loading,h=function(){d&&m(d,{left:b.plotLeft+"px",top:b.plotTop+"px",width:b.plotWidth+"px",height:b.plotHeight+"px"})};
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this.loadingDiv;b&&(b.className="highcharts-loading highcharts-loading-hidden",A(b,{opacity:0},{duration:a.loading.hideDuration||100,complete:function(){m(b,{display:"none"})}}));this.loadingShown=!1},propsRequireDirtyBox:"backgroundColor borderColor borderWidth margin marginTop marginRight marginBottom marginLeft spacing spacingTop spacingRight spacingBottom spacingLeft borderRadius plotBackgroundColor plotBackgroundImage plotBorderColor plotBorderWidth plotShadow shadow".split(" "),propsRequireUpdateSeries:"chart.inverted chart.polar chart.ignoreHiddenSeries chart.type colors plotOptions tooltip".split(" "),
update:function(a,d){var l=this,r={credits:"addCredits",title:"setTitle",subtitle:"setSubtitle"},n=a.chart,m,q;if(n){c(!0,l.options.chart,n);"className"in n&&l.setClassName(n.className);if("inverted"in n||"polar"in n)l.propFromSeries(),m=!0;"alignTicks"in n&&(m=!0);w(n,function(a,b){-1!==h("chart."+b,l.propsRequireUpdateSeries)&&(q=!0);-1!==h(b,l.propsRequireDirtyBox)&&(l.isDirtyBox=!0)});"style"in n&&l.renderer.setStyle(n.style)}a.colors&&(this.options.colors=a.colors);a.plotOptions&&c(!0,this.options.plotOptions,
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[a]);q=k.x;m=n.length;if(this.requireSorting&&q<n[m-1])for(p=!0;m&&n[m-1]>q;)m--;this.updateParallelArrays(k,"splice",m,0,0);this.updateParallelArrays(k,m);f&&k.name&&(f[q]=k.name);r.splice(m,0,a);p&&(this.data.splice(m,0,null),this.processData());"point"===h.legendType&&this.generatePoints();d&&(l[0]&&l[0].remove?l[0].remove(!1):(l.shift(),this.updateParallelArrays(k,"shift"),r.shift()));this.isDirtyData=this.isDirty=!0;c&&g.redraw(e)},removePoint:function(a,c,d){var e=this,h=e.data,g=h[a],k=e.points,
f=e.chart,r=function(){k&&k.length===h.length&&k.splice(a,1);h.splice(a,1);e.options.data.splice(a,1);e.updateParallelArrays(g||{series:e},"splice",a,1);g&&g.destroy();e.isDirty=!0;e.isDirtyData=!0;c&&f.redraw()};l(d,f);c=b(c,!0);g?g.firePointEvent("remove",null,r):r()},remove:function(a,c,d){function e(){h.destroy();l.isDirtyLegend=l.isDirtyBox=!0;l.linkSeries();b(a,!0)&&l.redraw(c)}var h=this,l=h.chart;!1!==d?u(h,"remove",null,e):e()},update:function(a,d){var e=this,h=e.chart,l=e.userOptions,g=
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d.cursor&&(z.cursor=d.cursor),f={fill:b.backgroundColor,stroke:b.borderColor,"stroke-width":b.borderWidth,r:b.borderRadius||0,rotation:n,padding:b.padding,zIndex:1},a.objectEach(f,function(a,b){void 0===a&&delete f[b]});!p||l&&G(m)?l&&G(m)&&(p?f.text=m:(p=e.dataLabel=v[n?"text":"label"](m,0,-9999,b.shape,null,null,b.useHTML,null,"data-label"),p.addClass("highcharts-data-label-color-"+e.colorIndex+" "+(b.className||"")+(b.useHTML?"highcharts-tracker":""))),p.attr(f),p.css(z).shadow(b.shadow),p.added||
p.add(r),c.alignDataLabel(e,p,b,null,w)):(e.dataLabel=p=p.destroy(),t&&(e.connector=t.destroy()))})};e.prototype.alignDataLabel=function(a,d,b,e,g){var c=this.chart,h=c.inverted,k=u(a.plotX,-9999),r=u(a.plotY,-9999),n=d.getBBox(),q,p=b.rotation,w=b.align,v=this.visible&&(a.series.forceDL||c.isInsidePlot(k,Math.round(r),h)||e&&c.isInsidePlot(k,h?e.x+1:e.y+e.height-1,h)),y="justify"===u(b.overflow,"justify");if(v&&(q=b.style.fontSize,q=c.renderer.fontMetrics(q,d).b,e=m({x:h?c.plotWidth-r:k,y:Math.round(h?
c.plotHeight-k:r),width:0,height:0},e),m(b,{width:n.width,height:n.height}),p?(y=!1,k=c.renderer.rotCorr(q,p),k={x:e.x+b.x+e.width/2+k.x,y:e.y+b.y+{top:0,middle:.5,bottom:1}[b.verticalAlign]*e.height},d[g?"attr":"animate"](k).attr({align:w}),r=(p+720)%360,r=180<r&&360>r,"left"===w?k.y-=r?n.height:0:"center"===w?(k.x-=n.width/2,k.y-=n.height/2):"right"===w&&(k.x-=n.width,k.y-=r?0:n.height)):(d.align(b,null,e),k=d.alignAttr),y?a.isLabelJustified=this.justifyDataLabel(d,b,k,n,e,g):u(b.crop,!0)&&(v=c.isInsidePlot(k.x,
k.y)&&c.isInsidePlot(k.x+n.width,k.y+n.height)),b.shape&&!p))d[g?"attr":"animate"]({anchorX:h?c.plotWidth-a.plotY:a.plotX,anchorY:h?c.plotHeight-a.plotX:a.plotY});v||(d.attr({y:-9999}),d.placed=!1)};e.prototype.justifyDataLabel=function(a,d,b,e,g,h){var c=this.chart,k=d.align,m=d.verticalAlign,n,q,p=a.box?0:a.padding||0;n=b.x+p;0>n&&("right"===k?d.align="left":d.x=-n,q=!0);n=b.x+e.width-p;n>c.plotWidth&&("left"===k?d.align="right":d.x=c.plotWidth-n,q=!0);n=b.y+p;0>n&&("bottom"===m?d.verticalAlign=
"top":d.y=-n,q=!0);n=b.y+e.height-p;n>c.plotHeight&&("top"===m?d.verticalAlign="bottom":d.y=c.plotHeight-n,q=!0);q&&(a.placed=!h,a.align(d,null,g));return q};n.pie&&(n.pie.prototype.drawDataLabels=function(){var c=this,d=c.data,b,g=c.chart,h=c.options.dataLabels,k=u(h.connectorPadding,10),l=u(h.connectorWidth,1),m=g.plotWidth,r=g.plotHeight,n,q=c.center,p=q[2]/2,v=q[1],C,L,f,t,K=[[],[]],J,N,O,P,x=[0,0,0,0];c.visible&&(h.enabled||c._hasPointLabels)&&(F(d,function(a){a.dataLabel&&a.visible&&a.dataLabel.shortened&&
(a.dataLabel.attr({width:"auto"}).css({width:"auto",textOverflow:"clip"}),a.dataLabel.shortened=!1)}),e.prototype.drawDataLabels.apply(c),F(d,function(a){a.dataLabel&&a.visible&&(K[a.half].push(a),a.dataLabel._pos=null)}),F(K,function(d,e){var l,n,u=d.length,w=[],z;if(u)for(c.sortByAngle(d,e-.5),0<c.maxLabelDistance&&(l=Math.max(0,v-p-c.maxLabelDistance),n=Math.min(v+p+c.maxLabelDistance,g.plotHeight),F(d,function(a){0<a.labelDistance&&a.dataLabel&&(a.top=Math.max(0,v-p-a.labelDistance),a.bottom=
Math.min(v+p+a.labelDistance,g.plotHeight),z=a.dataLabel.getBBox().height||21,a.positionsIndex=w.push({target:a.labelPos[1]-a.top+z/2,size:z,rank:a.y})-1)}),a.distribute(w,n+z-l)),P=0;P<u;P++)b=d[P],n=b.positionsIndex,f=b.labelPos,C=b.dataLabel,O=!1===b.visible?"hidden":"inherit",l=f[1],w&&G(w[n])?void 0===w[n].pos?O="hidden":(t=w[n].size,N=b.top+w[n].pos):N=l,delete b.positionIndex,J=h.justify?q[0]+(e?-1:1)*(p+b.labelDistance):c.getX(N<b.top+2||N>b.bottom-2?l:N,e,b),C._attr={visibility:O,align:f[6]},
C._pos={x:J+h.x+({left:k,right:-k}[f[6]]||0),y:N+h.y-10},f.x=J,f.y=N,L=C.getBBox().width,l=null,J-L<k?(l=Math.round(L-J+k),x[3]=Math.max(l,x[3])):J+L>m-k&&(l=Math.round(J+L-m+k),x[1]=Math.max(l,x[1])),0>N-t/2?x[0]=Math.max(Math.round(-N+t/2),x[0]):N+t/2>r&&(x[2]=Math.max(Math.round(N+t/2-r),x[2])),C.sideOverflow=l}),0===A(x)||this.verifyDataLabelOverflow(x))&&(this.placeDataLabels(),l&&F(this.points,function(a){var b;n=a.connector;if((C=a.dataLabel)&&C._pos&&a.visible&&0<a.labelDistance){O=C._attr.visibility;
if(b=!n)a.connector=n=g.renderer.path().addClass("highcharts-data-label-connector highcharts-color-"+a.colorIndex).add(c.dataLabelsGroup),n.attr({"stroke-width":l,stroke:h.connectorColor||a.color||"#666666"});n[b?"attr":"animate"]({d:c.connectorPath(a.labelPos)});n.attr("visibility",O)}else n&&(a.connector=n.destroy())}))},n.pie.prototype.connectorPath=function(a){var c=a.x,b=a.y;return u(this.options.dataLabels.softConnector,!0)?["M",c+("left"===a[6]?5:-5),b,"C",c,b,2*a[2]-a[4],2*a[3]-a[5],a[2],
a[3],"L",a[4],a[5]]:["M",c+("left"===a[6]?5:-5),b,"L",a[2],a[3],"L",a[4],a[5]]},n.pie.prototype.placeDataLabels=function(){F(this.points,function(a){var c=a.dataLabel;c&&a.visible&&((a=c._pos)?(c.sideOverflow&&(c._attr.width=c.getBBox().width-c.sideOverflow,c.css({width:c._attr.width+"px",textOverflow:"ellipsis"}),c.shortened=!0),c.attr(c._attr),c[c.moved?"animate":"attr"](a),c.moved=!0):c&&c.attr({y:-9999}))},this)},n.pie.prototype.alignDataLabel=v,n.pie.prototype.verifyDataLabelOverflow=function(a){var c=
this.center,b=this.options,d=b.center,e=b.minSize||80,g,l=null!==b.size;l||(null!==d[0]?g=Math.max(c[2]-Math.max(a[1],a[3]),e):(g=Math.max(c[2]-a[1]-a[3],e),c[0]+=(a[3]-a[1])/2),null!==d[1]?g=Math.max(Math.min(g,c[2]-Math.max(a[0],a[2])),e):(g=Math.max(Math.min(g,c[2]-a[0]-a[2]),e),c[1]+=(a[0]-a[2])/2),g<c[2]?(c[2]=g,c[3]=Math.min(h(b.innerSize||0,g),g),this.translate(c),this.drawDataLabels&&this.drawDataLabels()):l=!0);return l});n.column&&(n.column.prototype.alignDataLabel=function(a,d,b,g,h){var c=
this.chart.inverted,l=a.series,k=a.dlBox||a.shapeArgs,m=u(a.below,a.plotY>u(this.translatedThreshold,l.yAxis.len)),n=u(b.inside,!!this.options.stacking);k&&(g=q(k),0>g.y&&(g.height+=g.y,g.y=0),k=g.y+g.height-l.yAxis.len,0<k&&(g.height-=k),c&&(g={x:l.yAxis.len-g.y-g.height,y:l.xAxis.len-g.x-g.width,width:g.height,height:g.width}),n||(c?(g.x+=m?0:g.width,g.width=0):(g.y+=m?g.height:0,g.height=0)));b.align=u(b.align,!c||n?"center":m?"right":"left");b.verticalAlign=u(b.verticalAlign,c||n?"middle":m?"top":
"bottom");e.prototype.alignDataLabel.call(this,a,d,b,g,h);a.isLabelJustified&&a.contrastColor&&a.dataLabel.css({color:a.contrastColor})})})(K);(function(a){var C=a.Chart,A=a.each,G=a.pick,F=a.addEvent;C.prototype.callbacks.push(function(a){function g(){var g=[];A(a.series||[],function(a){var k=a.options.dataLabels,m=a.dataLabelCollections||["dataLabel"];(k.enabled||a._hasPointLabels)&&!k.allowOverlap&&a.visible&&A(m,function(h){A(a.points,function(a){a[h]&&(a[h].labelrank=G(a.labelrank,a.shapeArgs&&
a.shapeArgs.height),g.push(a[h]))})})});a.hideOverlappingLabels(g)}g();F(a,"redraw",g)});C.prototype.hideOverlappingLabels=function(a){var g=a.length,k,m,v,u,h,e,n,d,c,w=function(a,c,d,e,g,h,k,m){return!(g>a+d||g+k<a||h>c+e||h+m<c)};for(m=0;m<g;m++)if(k=a[m])k.oldOpacity=k.opacity,k.newOpacity=1;a.sort(function(a,c){return(c.labelrank||0)-(a.labelrank||0)});for(m=0;m<g;m++)for(v=a[m],k=m+1;k<g;++k)if(u=a[k],v&&u&&v!==u&&v.placed&&u.placed&&0!==v.newOpacity&&0!==u.newOpacity&&(h=v.alignAttr,e=u.alignAttr,
n=v.parentGroup,d=u.parentGroup,c=2*(v.box?0:v.padding),h=w(h.x+n.translateX,h.y+n.translateY,v.width-c,v.height-c,e.x+d.translateX,e.y+d.translateY,u.width-c,u.height-c)))(v.labelrank<u.labelrank?v:u).newOpacity=0;A(a,function(a){var b,c;a&&(c=a.newOpacity,a.oldOpacity!==c&&a.placed&&(c?a.show(!0):b=function(){a.hide()},a.alignAttr.opacity=c,a[a.isOld?"animate":"attr"](a.alignAttr,null,b)),a.isOld=!0)})}})(K);(function(a){var C=a.addEvent,A=a.Chart,G=a.createElement,F=a.css,m=a.defaultOptions,g=
a.defaultPlotOptions,k=a.each,q=a.extend,v=a.fireEvent,u=a.hasTouch,h=a.inArray,e=a.isObject,n=a.Legend,d=a.merge,c=a.pick,w=a.Point,b=a.Series,y=a.seriesTypes,D=a.svg,H;H=a.TrackerMixin={drawTrackerPoint:function(){var a=this,b=a.chart.pointer,c=function(a){var c=b.getPointFromEvent(a);void 0!==c&&(b.isDirectTouch=!0,c.onMouseOver(a))};k(a.points,function(a){a.graphic&&(a.graphic.element.point=a);a.dataLabel&&(a.dataLabel.div?a.dataLabel.div.point=a:a.dataLabel.element.point=a)});a._hasTracking||
(k(a.trackerGroups,function(d){if(a[d]){a[d].addClass("highcharts-tracker").on("mouseover",c).on("mouseout",function(a){b.onTrackerMouseOut(a)});if(u)a[d].on("touchstart",c);a.options.cursor&&a[d].css(F).css({cursor:a.options.cursor})}}),a._hasTracking=!0)},drawTrackerGraph:function(){var a=this,b=a.options,c=b.trackByArea,d=[].concat(c?a.areaPath:a.graphPath),e=d.length,g=a.chart,h=g.pointer,m=g.renderer,n=g.options.tooltip.snap,f=a.tracker,q,v=function(){if(g.hoverSeries!==a)a.onMouseOver()},w=
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b.cursor&&a.css({cursor:b.cursor});if(u)a.on("touchstart",v)}))}};y.column&&(y.column.prototype.drawTracker=H.drawTrackerPoint);y.pie&&(y.pie.prototype.drawTracker=H.drawTrackerPoint);y.scatter&&(y.scatter.prototype.drawTracker=H.drawTrackerPoint);q(n.prototype,{setItemEvents:function(a,b,c){var e=this,g=e.chart.renderer.boxWrapper,h="highcharts-legend-"+(a.series?"point":"series")+"-active";(c?b:a.legendGroup).on("mouseover",function(){a.setState("hover");g.addClass(h);b.css(e.options.itemHoverStyle)}).on("mouseout",
function(){b.css(d(a.visible?e.itemStyle:e.itemHiddenStyle));g.removeClass(h);a.setState()}).on("click",function(b){var c=function(){a.setVisible&&a.setVisible()};b={browserEvent:b};a.firePointEvent?a.firePointEvent("legendItemClick",b,c):v(a,"legendItemClick",b,c)})},createCheckboxForItem:function(a){a.checkbox=G("input",{type:"checkbox",checked:a.selected,defaultChecked:a.selected},this.options.itemCheckboxStyle,this.chart.container);C(a.checkbox,"click",function(b){v(a.series||a,"checkboxClick",
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v(a,"selection",{resetSelection:!0},function(){a.zoom()})},zoom:function(a){var b,d=this.pointer,g=!1,h;!a||a.resetSelection?k(this.axes,function(a){b=a.zoom()}):k(a.xAxis.concat(a.yAxis),function(a){var c=a.axis;d[c.isXAxis?"zoomX":"zoomY"]&&(b=c.zoom(a.min,a.max),c.displayBtn&&(g=!0))});h=this.resetZoomButton;g&&!h?this.showResetZoom():!g&&e(h)&&(this.resetZoomButton=h.destroy());b&&this.redraw(c(this.options.chart.animation,a&&a.animation,100>this.pointCount))},pan:function(a,b){var c=this,d=c.hoverPoints,
e;d&&k(d,function(a){a.setState()});k("xy"===b?[1,0]:[1],function(b){b=c[b?"xAxis":"yAxis"][0];var d=b.horiz,g=a[d?"chartX":"chartY"],d=d?"mouseDownX":"mouseDownY",h=c[d],f=(b.pointRange||0)/2,l=b.getExtremes(),k=b.toValue(h-g,!0)+f,f=b.toValue(h+b.len-g,!0)-f,m=f<k,h=m?f:k,k=m?k:f,f=Math.min(l.dataMin,b.toValue(b.toPixels(l.min)-b.minPixelPadding)),m=Math.max(l.dataMax,b.toValue(b.toPixels(l.max)+b.minPixelPadding)),n;n=f-h;0<n&&(k+=n,h=f);n=k-m;0<n&&(k=m,h-=n);b.series.length&&h!==l.min&&k!==l.max&&
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onMouseOver:function(a){var b=this.series.chart,c=b.pointer;a=a?c.normalize(a):c.getChartCoordinatesFromPoint(this,b.inverted);c.runPointActions(a,this)},onMouseOut:function(){var a=this.series.chart;this.firePointEvent("mouseOut");k(a.hoverPoints||[],function(a){a.setState()});a.hoverPoints=a.hoverPoint=null},importEvents:function(){if(!this.hasImportedEvents){var b=this,c=d(b.series.options.point,b.options).events;b.events=c;a.objectEach(c,function(a,c){C(b,c,a)});this.hasImportedEvents=!0}},setState:function(a,
b){var d=Math.floor(this.plotX),e=this.plotY,h=this.series,l=h.options.states[a]||{},k=g[h.type].marker&&h.options.marker,m=k&&!1===k.enabled,n=k&&k.states&&k.states[a]||{},f=!1===n.enabled,t=h.stateMarkerGraphic,u=this.marker||{},v=h.chart,w=h.halo,y,B=k&&h.markerAttribs;a=a||"";if(!(a===this.state&&!b||this.selected&&"select"!==a||!1===l.enabled||a&&(f||m&&!1===n.enabled)||a&&u.states&&u.states[a]&&!1===u.states[a].enabled)){B&&(y=h.markerAttribs(this,a));if(this.graphic)this.state&&this.graphic.removeClass("highcharts-point-"+
this.state),a&&this.graphic.addClass("highcharts-point-"+a),this.graphic.attr(h.pointAttribs(this,a)),y&&this.graphic.animate(y,c(v.options.chart.animation,n.animation,k.animation)),t&&t.hide();else{if(a&&n){k=u.symbol||h.symbol;t&&t.currentSymbol!==k&&(t=t.destroy());if(t)t[b?"animate":"attr"]({x:y.x,y:y.y});else k&&(h.stateMarkerGraphic=t=v.renderer.symbol(k,y.x,y.y,y.width,y.height).add(h.markerGroup),t.currentSymbol=k);t&&t.attr(h.pointAttribs(this,a))}t&&(t[a&&v.isInsidePlot(d,e,v.inverted)?
"show":"hide"](),t.element.point=this)}(d=l.halo)&&d.size?(w||(h.halo=w=v.renderer.path().add((this.graphic||t).parentGroup)),w[b?"animate":"attr"]({d:this.haloPath(d.size)}),w.attr({"class":"highcharts-halo highcharts-color-"+c(this.colorIndex,h.colorIndex)}),w.point=this,w.attr(q({fill:this.color||h.color,"fill-opacity":d.opacity,zIndex:-1},d.attributes))):w&&w.point&&w.point.haloPath&&w.animate({d:w.point.haloPath(0)});this.state=a}},haloPath:function(a){return this.series.chart.renderer.symbols.circle(Math.floor(this.plotX)-
a,this.plotY-a,2*a,2*a)}});q(b.prototype,{onMouseOver:function(){var a=this.chart,b=a.hoverSeries;if(b&&b!==this)b.onMouseOut();this.options.events.mouseOver&&v(this,"mouseOver");this.setState("hover");a.hoverSeries=this},onMouseOut:function(){var a=this.options,b=this.chart,c=b.tooltip,d=b.hoverPoint;b.hoverSeries=null;if(d)d.onMouseOut();this&&a.events.mouseOut&&v(this,"mouseOut");!c||this.stickyTracking||c.shared&&!this.noSharedTooltip||c.hide();this.setState()},setState:function(a){var b=this,
d=b.options,e=b.graph,g=d.states,h=d.lineWidth,d=0;a=a||"";if(b.state!==a&&(k([b.group,b.markerGroup,b.dataLabelsGroup],function(c){c&&(b.state&&c.removeClass("highcharts-series-"+b.state),a&&c.addClass("highcharts-series-"+a))}),b.state=a,!g[a]||!1!==g[a].enabled)&&(a&&(h=g[a].lineWidth||h+(g[a].lineWidthPlus||0)),e&&!e.dashstyle))for(h={"stroke-width":h},e.animate(h,c(b.chart.options.chart.animation,g[a]&&g[a].animation));b["zone-graph-"+d];)b["zone-graph-"+d].attr(h),d+=1},setVisible:function(a,
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Highcharts JS v5.0.12 (2017-05-24)
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0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACCGCT": [76, 1], "AACCCC": [4403, 54, 8, 7, 8, 1, 1], "AACCCG": [108, 5, 1, 2, 0, 1, 1], "AACGTT": [46], "ACCCTG": [3194, 51, 16, 12, 3], "ACCGCG": [78, 2], "AGCGG": [333, 22, 4, 2], "ACCGCC": [1020, 29, 8, 5, 2], "AAAGGT": [2782, 6, 1], "AACTGG": [2956, 12], "ACGTAG": [73], "AACTGT": [2350, 11], "AGCGC": [294, 26, 2, 1, 1], "AAAGGG": [10597, 193, 32, 8, 1, 6, 3, 0, 1, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACGTAT": [353, 13, 3], "AAAGGC": [4744, 16, 1], "AGCCCC": [11460, 253, 75, 27, 8, 5, 1, 0, 0, 1], "AATT": [0, 7552, 1629, 581, 237, 67, 19, 4], "AAGGTG": [3770, 19, 0, 1], "AAAAT": [78463, 25160, 6773, 2325, 768, 350, 307, 307, 252, 209, 155, 110, 51, 26, 17, 7, 2, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AATC": [0, 4134, 917, 469, 225, 111, 51, 18, 3], "AATG": [0, 25546, 4703, 1544, 855, 436, 235, 146, 76, 26, 7, 1], "AAAAC": [56856, 31889, 11926, 3964, 1156, 475, 311, 199, 72, 21, 10, 0, 1], "AAAAG": [79855, 18949, 4615, 1092, 258, 117, 62, 57, 53, 45, 44, 37, 17, 14, 7, 7, 6, 2, 1, 0, 0, 0, 0, 1], "AAG": [0, 0, 11244, 3398, 1382, 532, 243, 118, 83, 50, 38, 29, 34, 36, 34, 33, 45, 40, 35, 36, 41, 46, 34, 28, 24, 13, 16, 8, 8, 7, 4, 3, 0, 1, 0, 0, 0, 0, 2, 0, 0, 0, 1, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 1], "AAC": [0, 0, 24092, 11009, 5089, 2553, 1268, 681, 401, 242, 149, 122, 77, 55, 22, 9, 2], "ACGCAG": [219, 2], "ACCG": [0, 39, 3, 0, 1, 1], "ACCC": [0, 6870, 725, 151, 41, 10, 2, 1, 0, 1], "AAT": [0, 0, 40783, 12362, 5808, 2783, 1427, 909, 679, 569, 544, 567, 555, 409, 223, 97, 29, 8, 1], "AGGGCG": [594, 19, 6, 2], "AGGGCC": [6968, 132, 31, 7, 3], "ACCT": [0, 1798, 333, 130, 56, 19, 14, 9, 10, 5, 9, 5, 1], "ACGCAT": [104], "ACTCCT": [1658, 4, 2], "AACTGC": [1731, 4], "AGGGGG": [15609, 556, 122, 38, 13, 6, 4, 4, 1, 1, 2], "ACTCCG": 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[8217, 29, 4], "AAAGCT": [2577, 7], "ACCTC": [2757, 116, 9, 3, 1], "ACCTG": [1544, 55, 1], "AAATTT": [14224, 243, 16], "AAAGCC": [3939, 12, 3, 1], "CCGCGG": [526], "AAAGCG": [188], "AGAGCG": [691, 24, 5, 2, 2], "AAAATT": [41233, 690, 69, 7, 1], "AGAGCC": [4500, 40, 9, 1], "ACTGG": [1509, 62, 3, 1], "ACTGC": [11665, 160, 18, 3, 0, 0, 2], "AAAATG": [25575, 76, 5], "AGAGCT": [1299, 5, 1], "AAAATC": [12420, 69, 4], "AAGG": [0, 27911, 9886, 3924, 1590, 717, 497, 451, 503, 521, 564, 537, 469, 352, 271, 149, 55, 44, 11, 3, 1, 1, 1, 1, 0, 1, 0, 1, 0, 0, 0, 1, 0, 0, 1, 2, 0, 1], "AAGC": [0, 2857, 360, 117, 53, 29, 17, 9, 9, 8, 4, 3, 4], "ACGT": [0, 24, 1, 1, 0, 1], "ACATAG": [2856, 40, 6, 2, 1, 0, 1, 0, 3, 1], "ATCCCG": [90, 1, 0, 1], "ACGC": [0, 679, 98, 36, 9, 2, 2, 0, 0, 0, 1], "AAGT": [0, 1622, 114, 37, 17, 4, 2, 2, 1, 1], "ATCCCC": [6318, 51, 9, 1, 1, 2, 0, 1], "ACGG": [0, 181, 41, 14, 5, 3, 2, 3, 1, 1, 0, 1], "AGGGGC": [9892, 166, 33, 13, 6, 1, 2, 1, 1], "ACATAT": [27835, 767, 81, 16, 14, 21, 19, 17, 17, 8, 3, 2, 2], "AAAAGG": [20311, 183, 26, 7, 2], "AGATG": [4219, 455, 63, 8, 1, 1, 2, 3, 1, 2, 0, 0, 1, 1, 1], "AATCCT": [1813, 14, 0, 1], "AACATT": [5615, 16, 1], "AGCATG": [2689, 6], "AGCATC": [4611, 36, 7, 2, 1, 1, 1], "ACCAT": [1113, 53, 4, 1, 1, 3, 1, 4, 2, 1, 1], "ACACTC": [4907, 77, 6], "AACATG": [3871, 21, 1, 1, 0, 0, 0, 0, 1], "ACACTG": [2432, 5], "AACATC": [6056, 51, 4, 1, 1], "C": [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1377, 796, 468, 262, 165, 111, 72, 48, 24, 19, 9, 8, 8, 4, 1, 6, 1, 6, 2, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAATAC": [13514, 94, 3, 2, 1, 1, 0, 1], "ACCGGG": [289, 10], "AAATAG": [14924, 65, 5, 1], "AGCCG": [278, 42, 5, 4, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ATGCC": [1887, 82, 14, 2, 1], "AACTTC": [2782, 7], "AGCCC": [8062, 759, 132, 43, 12, 6, 7, 1, 3], "AACTTG": [3638, 9], "AATCCC": [1725, 3, 1], "AAATAT": [33673, 528, 31, 9, 9, 1, 1, 1, 1], "AATCCG": [85], "ACCAG": [1694, 92, 14, 3, 5, 1], "AGCCT": [1385, 50, 3, 2], "AGGCGG": [12602, 75, 10, 5, 0, 0, 0, 1], "AGGCGC": [1015, 16, 5], "ACAGCC": [5712, 50, 7, 0, 0, 1], "ACAGCG": [205, 1], "ACAGCT": [1742, 8, 1], "AACGCT": [66], "ACCCCT": [2115, 23, 5, 2, 3, 0, 0, 1], "AAACAG": [17118, 49, 6, 1], "AAACAC": [10106, 68, 4, 1], "AACGCG": [16], "ACCCCC": [23424, 601, 70, 17, 2, 1, 1, 1], "AACGCC": [109, 1], "ACCCCG": [532, 20, 5], "AAACAT": [8470, 36, 1, 1, 1], "AACTAT": [2511, 3, 1], "AACACT": [2782, 15, 2, 0, 0, 1], "AGCTC": [3743, 201, 32, 8, 2], "CCCCGG": [2407, 95, 37, 9, 3, 0, 1, 3], "AACTAG": [22631, 19, 4], "AACTAC": [1721, 3], "AGAT": [0, 9326, 2761, 1152, 665, 447, 358, 511, 983, 1389, 995, 542, 243, 86, 38, 9], "AACACG": [143, 1], "AACACC": [2458, 16, 3, 1], "AAAGAC": [9706, 37, 1], "ACACG": [50, 5, 1], "ACACC": [7813, 463, 34, 3, 0, 0, 0, 0, 0, 2], "CG": [0, 0, 0, 0, 479, 224, 130, 83, 26, 12, 11, 4, 1], "ATATC": [2968, 187, 30, 12, 2, 4, 5, 3, 3], "ACACT": [1358, 74, 13, 2, 1, 0, 2, 4, 1], "ATATCC": [2286, 15, 4, 1, 0, 1], "AAGGGG": [11679, 390, 74, 31, 12, 4, 4], "AAGGGC": [3073, 35, 3], "ACTCT": [1215, 39, 7, 4, 0, 1, 0, 3, 1, 2, 1, 1], "AGAGGC": [19590, 118, 26, 7, 8, 0, 1, 1], "AAGGGT": [1083, 6], "AGAGGG": [17412, 1231, 472, 196, 80, 61, 20, 20, 8, 5, 5, 1, 2, 1, 0, 0, 1, 1, 1, 0, 1, 1, 2, 1, 0, 0, 0, 0, 1, 0, 2, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 1], "ACTCC": [5626, 661, 170, 42, 9, 4, 6, 1], "ACTCG": [26, 1], "AAGAC": [2833, 154, 16, 7, 2, 1, 3, 1, 2, 0, 2], "ACTGCT": [1999, 15, 4, 1, 0, 0, 1], "AACC": [0, 3210, 574, 194, 73, 40, 21, 21, 22, 13, 5, 3, 1, 1], "AACG": [0, 98, 14, 2, 1, 1, 0, 0, 0, 0, 1], "ACTGCC": [5317, 68, 11, 1], "ACTGCG": [89], "ATCCGC": [130, 0, 2], "ATCCGG": [46], "AACT": [0, 883, 94, 40, 18, 11, 3, 0, 2, 1, 4], "ACCGGC": [373, 1], "AGCTAT": [734, 3, 2], "AACTT": [1036, 14], "ATGC": [0, 2316, 151, 21, 4], "AAGCG": [62, 5], "AAGCC": [3167, 99, 8, 1], "AATACC": [1955, 8, 1, 0, 1], "AAGCT": [1271, 67, 3], "AACTG": [2934, 172, 5, 1], "AGCGGC": [1175, 40, 9, 3, 0, 0, 1], "AACTC": [1999, 67, 5, 1], "ACGAGT": [42], "AGGCCC": [7105, 82, 11, 0, 1], "AGGCCG": [3911, 45, 6], "ACGAGG": [439, 14, 1], "ACGAGC": [119], "AGGCCT": [537], "AAGTAC": [1576, 4], "AAGTAG": [3448, 11, 1], "AACGGT": [47], "AACGGC": [129, 1], "CCG": [0, 0, 2832, 1079, 578, 271, 152, 78, 48, 29, 14, 8, 4, 3, 3, 2, 1, 1, 0, 0, 0, 1], "AACGGG": [184, 1], "AAGTAT": [2014, 3, 0, 0, 0, 0, 0, 1], "AGGCC": [6241, 386, 33, 5, 1], "AATGCT": [2045, 11, 1], "AGGCG": [324, 44, 12, 2, 1], "AAGCTT": [621, 2], "AAGACT": [1420, 5], "AATGCG": [75], "AATGCC": [1741, 4, 1], "AAGCTC": [1790, 14], "CCCCCG": [5852, 208, 42, 15, 2, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAGCTG": [3939, 17, 1], "AACGG": [196, 48, 16, 4, 1, 2, 1, 0, 1], "ACAGC": [4426, 263, 37, 10, 5, 2, 1, 3, 2, 3, 2, 1], "ACAGG": [2881, 171, 23, 11, 9, 4, 3, 6, 2, 0, 1], "ACAGT": [1906, 93, 10, 2, 5, 1, 0, 1], "AATCTG": [5600, 16, 2], "AATAC": [3875, 251, 52, 16, 5, 2, 2, 6, 12, 7, 17, 8, 9, 4, 5, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 1], "AATCTC": [2392, 13, 0, 0, 0, 1], "AATAG": [6200, 419, 55, 13, 12, 8, 6, 7, 10, 19, 10, 17, 11, 6, 9, 5, 4, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAGGCC": [4681, 32, 4], "AAGGCG": [283, 2, 2], "ATGCCC": [2615, 8, 2], "ACGGC": [122, 3, 1], "AATAT": [13239, 3059, 289, 73, 30, 11, 16, 29, 27, 20, 6, 1], "AAGGCT": [1035, 3], "ACTAGT": [426, 2], "ACGCTG": [182], "ACGCTC": [243, 0, 0, 0, 1], "ACTAGG": [969, 5, 1], "ACTAGC": [703, 2], "ACTGGG": [2608, 11, 6], "ATCATG": [1088, 12, 1, 0, 2], "AATTGC": [2074, 1], "ACTGGC": [2125, 11], "AACCAC": [2194, 16, 3], "AACCAG": [3052, 10], "ACGGG": [227, 20, 7, 5, 3], "AACCAT": [1536, 7, 2], "ACC": [0, 0, 9019, 2210, 802, 372, 192, 105, 62, 26, 17, 18, 20, 16, 7, 7, 5, 1, 1, 1, 1, 0, 1, 1, 0, 0, 0, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACGTCG": [8], "AACAGC": [4699, 34, 5, 0, 1], "ACCTAG": [920, 8], "ACGTCC": [328, 6, 2], "AACAGG": [4301, 14], "AAGAAT": [7550, 49, 8, 2, 0, 0, 1], "ACACCG": [138], "AAGGC": [2691, 268, 44, 19, 7, 1], "ACACCC": [5638, 98, 22, 4, 1, 1], "AAGGG": [11761, 2176, 491, 149, 71, 37, 22, 17, 28, 20, 24, 12, 14, 9, 7, 2, 0, 1, 1, 1, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACCTAT": [1258, 14, 6, 3, 1, 1], "ATCG": [0, 45, 5, 2], "AACAGT": [2754, 9], "ACACCT": [1035, 5, 0, 1], "AAGGT": [1256, 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0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1], "AGGGGC": [6031, 2113, 1027, 459, 191, 71, 45, 28, 34, 27, 16, 16, 11, 4, 7, 5, 3, 3, 5, 2, 0, 0, 3, 3, 1, 2, 1, 0, 1, 1, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1], "ACATAT": [11060, 8579, 3133, 2456, 1040, 1567, 205, 236, 77, 104, 55, 90, 13, 23, 9, 10, 7, 19, 1, 2, 5, 3, 2, 3, 0, 3, 0, 1, 4, 6, 1, 2, 6, 2, 2, 8, 2, 2, 1, 6, 5, 3, 2, 3, 4, 1, 5, 2, 2, 3, 3, 3, 4, 2, 0, 2, 2, 2, 0, 2, 1, 1, 0, 0, 1, 0, 0, 0, 1, 1, 0, 0, 1, 0, 0, 1], "AAAAGG": [12565, 4357, 1840, 795, 521, 233, 60, 28, 34, 25, 21, 15, 4, 5, 10, 3, 3, 1, 2, 1, 1, 0, 0, 3, 0, 1, 0, 0, 1], "AGATG": [2718, 1018, 483, 292, 55, 40, 36, 32, 53, 3, 5, 1, 1, 6, 0, 0, 2, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 1, 0, 0, 2, 0, 0, 0, 1, 0, 0, 0, 0, 1, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1], "AATCCT": [1271, 336, 125, 51, 19, 11, 3, 8, 0, 2, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AACATT": [3875, 1116, 405, 145, 50, 24, 7, 2, 1, 4, 0, 2, 0, 0, 0, 1], "AGCATG": [1799, 691, 131, 45, 17, 6, 2, 1, 1, 1, 1], "AGCATC": [2295, 1007, 1093, 105, 64, 47, 6, 8, 11, 4, 1, 6, 2, 1, 1, 1, 0, 2, 0, 0, 2, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACCAT": [799, 233, 81, 24, 9, 12, 3, 5, 2, 0, 0, 1, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 2, 0, 0, 1, 0, 0, 1, 1, 0, 0, 2, 0, 1, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1], "ACACTC": [2591, 1135, 527, 284, 176, 194, 21, 18, 17, 8, 7, 6, 2, 1, 1, 1, 0, 1], "AACATG": [2719, 781, 244, 81, 33, 13, 3, 8, 3, 1, 3, 3, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACACTG": [1706, 514, 150, 44, 12, 6, 3, 0, 0, 2], "AACATC": [2763, 976, 1902, 128, 227, 60, 25, 5, 9, 4, 5, 3, 2, 0, 0, 0, 1, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1], "C": [1377, 796, 468, 262, 165, 111, 72, 48, 24, 19, 9, 8, 8, 4, 1, 6, 1, 6, 2, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAATAC": [9547, 2409, 828, 463, 163, 104, 31, 12, 12, 34, 1, 4, 0, 2, 1, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACCGGG": [212, 43, 17, 9, 6, 2, 2, 6, 1, 0, 0, 1], "AAATAG": [9347, 3699, 1127, 465, 182, 104, 33, 14, 10, 3, 3, 2, 2, 2, 0, 0, 1, 0, 1], "AGCCG": [145, 114, 19, 25, 9, 4, 2, 2, 1, 1, 1, 2, 0, 1, 1, 1, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ATGCC": [1300, 425, 162, 39, 16, 10, 9, 8, 6, 4, 1, 1, 2, 0, 0, 2, 0, 0, 0, 1], "AACTTC": [1905, 614, 190, 48, 19, 6, 5, 1, 0, 0, 1], "AGCCC": [5025, 2203, 834, 345, 164, 93, 102, 55, 35, 38, 23, 19, 17, 10, 11, 3, 6, 13, 5, 0, 2, 2, 3, 1, 1, 0, 1, 3, 0, 1, 0, 5, 1, 0, 1, 0, 0, 0, 0, 1, 0, 2], "AACTTG": [2321, 809, 348, 103, 50, 7, 6, 0, 2, 0, 0, 1], "AATCCC": [1143, 389, 141, 35, 9, 8, 1, 1, 0, 1, 0, 0, 1], "AAATAT": [19149, 8299, 2926, 1543, 722, 1034, 204, 122, 52, 53, 39, 58, 11, 4, 7, 5, 0, 4, 2, 2, 2, 1, 0, 2, 3, 0, 1, 2, 0, 3, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AATCCG": [75, 7, 1, 0, 2], "ACCAG": [1222, 348, 124, 36, 17, 19, 11, 9, 1, 5, 5, 1, 2, 0, 0, 2, 0, 1, 1, 1, 2, 0, 1, 1], "AGCCT": [1128, 193, 64, 14, 16, 16, 1, 3, 0, 2, 1, 0, 0, 1, 1], "AGGCGG": [10578, 508, 1310, 117, 32, 57, 26, 10, 23, 3, 1, 12, 1, 1, 3, 0, 0, 5, 0, 0, 4, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AGGCGC": [596, 337, 48, 24, 6, 4, 5, 8, 2, 0, 1, 0, 4, 0, 0, 1], "ACAGCC": [3677, 1251, 430, 218, 80, 56, 14, 12, 12, 7, 0, 5, 1, 3, 1, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACAGCG": [136, 39, 20, 6, 3, 1, 0, 0, 0, 0, 1], "ACAGCT": [1146, 445, 89, 41, 15, 6, 3, 1, 1, 0, 0, 3, 0, 0, 0, 1], "AACGCT": [48, 14, 0, 0, 2, 2], "ACCCCT": [1329, 447, 172, 75, 66, 26, 3, 4, 3, 8, 0, 5, 1, 1, 0, 0, 2, 1, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAACAG": [10535, 4865, 1022, 464, 158, 74, 25, 9, 8, 4, 2, 1, 2, 1, 1, 0, 0, 2, 1], "AAACAC": [5280, 3335, 694, 449, 132, 216, 16, 32, 3, 8, 2, 7, 2, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 1], "AACGCG": [12, 1, 2, 1], "ACCCCC": [12163, 5318, 2864, 1555, 1010, 514, 228, 120, 81, 63, 64, 45, 22, 12, 10, 13, 10, 3, 6, 1, 0, 2, 2, 6, 0, 0, 1, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1], "AACGCC": [85, 17, 3, 0, 1, 3, 0, 0, 0, 1], "ACCCCG": [364, 94, 34, 19, 13, 8, 5, 2, 3, 3, 3, 4, 2, 0, 0, 0, 1, 2], "AAACAT": [5505, 1889, 641, 298, 94, 43, 13, 10, 6, 5, 0, 2, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 1], "AACTAT": [1673, 536, 179, 66, 48, 9, 2, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AACACT": [1198, 874, 355, 315, 25, 15, 2, 6, 7, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AGCTC": [2515, 834, 394, 95, 48, 23, 10, 25, 10, 8, 8, 1, 5, 2, 0, 3, 2, 1, 0, 0, 1, 1], "CCCCGG": [1416, 482, 220, 155, 73, 61, 16, 15, 17, 18, 12, 17, 9, 3, 6, 8, 5, 6, 4, 3, 0, 1, 1, 0, 0, 2, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 2], "AACTAG": [21635, 557, 211, 150, 59, 19, 9, 4, 4, 1, 1, 0, 1, 0, 0, 0, 2, 1], "AACTAC": [1103, 413, 143, 39, 17, 6, 2, 1], "AGAT": [3843, 2210, 1603, 1670, 896, 639, 605, 621, 349, 271, 251, 281, 186, 145, 149, 185, 122, 97, 110, 118, 79, 66, 83, 130, 115, 91, 117, 188, 182, 173, 267, 361, 381, 273, 378, 357, 298, 232, 225, 240, 160, 152, 101, 129, 78, 67, 49, 49, 35, 25, 13, 13, 13, 10, 9, 6, 0, 4, 3, 2], "AACACG": [113, 20, 5, 4, 0, 1, 1], "AACACC": [1586, 490, 225, 82, 49, 26, 3, 3, 2, 3, 2, 3, 2, 0, 0, 0, 0, 1, 0, 0, 0, 1], "AAAGAC": [5969, 2481, 681, 377, 106, 92, 16, 9, 3, 4, 2, 3, 0, 0, 1], "ACACG": [36, 10, 4, 2, 1, 1, 1, 0, 0, 0, 0, 0, 1], "ACACC": [2128, 979, 4706, 347, 64, 21, 14, 17, 25, 2, 3, 2, 2, 1, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1], "CG": [266, 213, 125, 99, 79, 51, 55, 28, 14, 12, 6, 6, 8, 3, 3, 1, 1], "ATATC": [1945, 626, 397, 90, 38, 28, 16, 15, 11, 5, 3, 5, 6, 3, 2, 1, 3, 3, 0, 1, 0, 0, 1, 0, 1, 1, 1, 1, 1, 0, 0, 1, 3, 1, 1, 0, 1, 0, 0, 0, 2, 1], "ACACT": [992, 236, 130, 27, 15, 9, 11, 12, 3, 2, 5, 1, 2, 0, 0, 0, 0, 2, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 1, 0, 0, 0, 3, 0, 0, 1], "ATATCC": [1404, 531, 184, 93, 45, 29, 4, 3, 5, 0, 2, 1, 0, 0, 1, 0, 1, 2, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAGGGG": [6561, 2560, 1304, 567, 439, 248, 105, 86, 76, 41, 41, 41, 12, 18, 20, 7, 12, 5, 6, 7, 10, 1, 1, 6, 1, 2, 3, 2, 2, 2, 1, 1, 1, 0, 0, 1, 0, 1, 1, 0, 2], "AAGGGC": [1816, 867, 229, 115, 37, 9, 18, 8, 3, 4, 1, 1, 0, 2, 0, 0, 0, 1], "ACTCT": [891, 246, 78, 17, 10, 6, 3, 3, 2, 2, 1, 1, 1, 2, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 2, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 2, 0, 0, 0, 0, 1, 0, 0, 0, 1], "AGAGGC": [9187, 8080, 1624, 419, 207, 73, 20, 35, 21, 16, 12, 14, 7, 6, 2, 3, 5, 3, 1, 1, 2, 1, 2, 0, 2, 0, 1, 1, 1, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1], "AAGGGT": [776, 194, 71, 20, 13, 9, 0, 0, 1, 5], "AGAGGG": [9134, 3807, 1611, 971, 1319, 570, 448, 189, 154, 151, 145, 144, 118, 96, 79, 70, 56, 53, 43, 61, 33, 26, 18, 15, 23, 14, 14, 12, 7, 10, 13, 17, 7, 10, 8, 6, 7, 3, 4, 1, 2, 3, 7, 4, 1, 6, 1, 1, 1, 1, 1, 2, 0, 3, 0, 2, 1, 0, 2, 0, 0, 2, 0, 1, 2, 0, 0, 0, 0, 0, 1, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1], "ACTCC": [2530, 2541, 555, 193, 174, 107, 69, 118, 43, 53, 26, 19, 29, 14, 11, 5, 4, 8, 2, 1, 3, 1, 2, 3, 0, 0, 0, 1, 2, 1, 0, 1, 2, 0, 0, 1], "ACTCG": [18, 6, 2, 1], "AAGAC": [2011, 558, 264, 61, 48, 18, 11, 16, 6, 4, 3, 3, 0, 0, 4, 0, 1, 2, 1, 1, 0, 0, 0, 0, 1, 0, 0, 0, 1, 1, 1, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 1], "ACTGCT": [1273, 416, 183, 69, 39, 19, 7, 3, 3, 0, 1, 1, 1, 0, 1, 0, 0, 2, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AACC": [1514, 613, 661, 422, 200, 99, 170, 105, 56, 33, 52, 53, 18, 13, 22, 20, 11, 4, 17, 8, 6, 4, 6, 5, 3, 4, 7, 7, 4, 4, 4, 10, 3, 2, 6, 2, 0, 3, 2, 0, 0, 2, 1, 0, 0, 0, 1, 0, 0, 1], "AACG": [56, 9, 7, 26, 6, 1, 2, 5, 1, 0, 1, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACTGCC": [3184, 1304, 435, 259, 99, 36, 32, 13, 6, 12, 4, 1, 1, 5, 1, 3, 1, 0, 0, 1], "ACTGCG": [73, 9, 1, 3, 2, 1], "ATCCGC": [100, 18, 8, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2], "ATCCGG": [34, 4, 4, 2, 2], "AACT": [517, 169, 135, 62, 25, 24, 19, 26, 12, 5, 11, 12, 6, 1, 3, 8, 3, 1, 3, 4, 0, 0, 2, 1, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 0, 0, 3, 1], "ACCGGC": [187, 88, 80, 12, 2, 4, 0, 1], "AGCTAT": [466, 158, 54, 23, 23, 10, 3, 0, 0, 0, 0, 0, 0, 0, 2], "AACTT": [864, 139, 33, 8, 3, 3], "ATGC": [1241, 489, 382, 204, 63, 24, 31, 33, 5, 2, 8, 6, 0, 3, 0, 1], "AAGCG": [43, 13, 6, 3, 0, 0, 0, 2], "AAGCC": [1710, 1295, 162, 58, 19, 10, 9, 3, 3, 1, 1, 1, 2, 0, 0, 0, 1], "AATACC": [1420, 366, 107, 36, 18, 8, 4, 0, 1, 2, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAGCT": [845, 268, 158, 33, 15, 15, 2, 2, 0, 0, 2, 1], "AACTG": [2083, 599, 252, 84, 47, 20, 9, 12, 3, 1, 0, 1, 0, 0, 0, 0, 0, 1], "AGCGGC": [696, 222, 136, 45, 26, 50, 8, 10, 4, 10, 3, 5, 2, 1, 2, 3, 0, 1, 1, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AACTC": [1516, 384, 99, 43, 12, 10, 1, 1, 2, 0, 2, 0, 1, 1], "ACGAGT": [28, 12, 1, 1], "AGGCCC": [4553, 1543, 627, 219, 108, 55, 21, 15, 20, 16, 4, 6, 2, 2, 2, 3, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AGGCCG": [2073, 1661, 86, 34, 25, 32, 11, 18, 5, 2, 4, 5, 5, 0, 1], "ACGAGG": [281, 68, 59, 11, 8, 12, 6, 1, 3, 1, 1, 2, 1], "ACGAGC": [99, 16, 3, 1], "AGGCCT": [387, 94, 36, 17, 2, 1], "AAGTAC": [1150, 286, 104, 22, 13, 1, 3, 0, 1], "AAGTAG": [2383, 684, 239, 88, 36, 18, 5, 1, 1, 2, 0, 2, 0, 0, 0, 0, 0, 1], "AACGGT": [35, 7, 5], "AACGGC": [99, 21, 8, 1, 0, 0, 0, 1], "CCG": [1376, 784, 672, 492, 295, 292, 246, 156, 176, 116, 61, 94, 55, 39, 58, 30, 27, 21, 14, 15, 19, 12, 11, 6, 6, 4, 4, 4, 1, 3, 3, 1, 0, 1, 0, 2, 0, 1, 2, 1, 1, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AACGGG": [130, 31, 12, 7, 3, 1, 0, 1], "AAGTAT": [1501, 365, 107, 27, 12, 2, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AGGCC": [4080, 1580, 581, 194, 85, 59, 26, 22, 12, 10, 6, 3, 2, 1, 2, 1, 0, 1, 0, 1], "AATGCT": [1382, 417, 176, 47, 18, 5, 3, 2, 4, 0, 0, 2, 1], "AGGCG": [198, 72, 54, 19, 10, 9, 2, 4, 4, 3, 4, 0, 1, 2, 0, 0, 0, 0, 1], "AAGCTT": [441, 108, 54, 13, 5, 0, 0, 2], "AAGACT": [979, 286, 90, 45, 15, 5, 2, 0, 1, 2], "AATGCG": [64, 8, 3], "AATGCC": [1215, 316, 134, 52, 15, 9, 2, 1, 1, 0, 0, 0, 1], "AAGCTC": [1193, 425, 136, 21, 11, 4, 7, 4, 2, 0, 0, 1], "CCCCCG": [3006, 1348, 750, 423, 204, 121, 64, 36, 30, 33, 21, 24, 9, 9, 9, 10, 5, 0, 4, 1, 3, 3, 2, 2, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AAGCTG": [2627, 879, 294, 95, 32, 12, 7, 2, 2, 2, 2, 2, 1], "AACGG": [54, 74, 68, 8, 3, 0, 5, 32, 1, 1, 2, 2, 10, 0, 1, 1, 1, 1, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACAGC": [2909, 941, 576, 132, 56, 32, 21, 22, 12, 10, 2, 5, 8, 3, 2, 1, 1, 3, 0, 2, 0, 1, 2, 1, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 2, 0, 1, 1, 0, 0, 0, 1, 0, 0, 0, 0, 3, 1, 0, 0, 0, 1, 1], "ACAGG": [1982, 618, 281, 78, 31, 23, 12, 27, 6, 3, 4, 2, 8, 1, 3, 3, 2, 2, 3, 1, 0, 0, 5, 0, 1, 0, 0, 3, 0, 0, 1, 0, 2, 0, 0, 2, 0, 4, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACAGT": [1304, 428, 174, 41, 25, 13, 5, 9, 3, 3, 2, 0, 2, 1, 0, 0, 0, 1, 0, 1, 0, 1, 3, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "AATCTG": [4234, 859, 324, 127, 38, 18, 7, 3, 3, 3, 0, 0, 1, 0, 0, 1], "AATAC": [2508, 953, 414, 108, 39, 36, 22, 46, 13, 15, 6, 5, 13, 2, 5, 2, 4, 3, 1, 2, 0, 0, 2, 0, 0, 1, 0, 1, 0, 1, 1, 0, 0, 0, 2, 2, 0, 2, 2, 6, 1, 1, 2, 3, 2, 0, 0, 2, 3, 3, 5, 2, 4, 2, 3, 1, 0, 2, 3, 3, 1, 1, 1, 2, 1, 1, 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0, 0, 0, 2], "ATGCCC": [1797, 437, 277, 76, 18, 10, 1, 1, 1, 2, 2, 1, 1, 0, 0, 0, 0, 1], "ACGGC": [80, 31, 11, 1, 0, 1, 0, 1, 0, 0, 0, 0, 1], "AATAT": [8458, 3240, 1541, 2251, 400, 196, 123, 89, 159, 49, 40, 21, 20, 33, 16, 15, 5, 4, 9, 7, 4, 6, 4, 2, 4, 0, 1, 4, 3, 3, 1, 2, 7, 9, 5, 5, 6, 4, 10, 5, 5, 4, 3, 3, 8, 1, 6, 2, 2, 1, 2, 0, 1, 0, 0, 0, 0, 1], "AAGGCT": [738, 185, 82, 18, 10, 2, 2, 0, 0, 0, 0, 1], "ACTAGT": [293, 77, 39, 8, 5, 4, 0, 1, 0, 0, 1], "ACGCTG": [137, 28, 14, 3], "ACGCTC": [161, 40, 26, 12, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1], "ACTAGG": [706, 172, 65, 16, 8, 2, 3, 1, 0, 0, 0, 1, 0, 1], "ACTAGC": [507, 132, 51, 9, 3, 1, 1, 0, 0, 1], "ACTGGG": [1733, 495, 222, 116, 25, 17, 1, 3, 3, 4, 0, 0, 2, 0, 0, 1, 0, 3], "ATCATG": [717, 209, 98, 31, 18, 15, 5, 1, 1, 0, 1, 4, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2], "AATTGC": [1782, 176, 72, 30, 14, 0, 0, 1], "ACTGGC": [1494, 434, 123, 49, 21, 4, 2, 5, 1, 2, 1], "AACCAC": [1408, 463, 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e.classList.add(this.main.config.content),e},e.prototype.searchDiv=function(){var e=this,t=document.createElement("div");t.classList.add(this.main.config.search),this.main.config.showSearch||(t.style.display="none");var i=document.createElement("input");return i.type="search",i.placeholder="Search",i.tabIndex=0,i.onclick=function(t){setTimeout(function(){""===t.target.value&&e.main.search("")},10)},i.onkeydown=function(t){"ArrowUp"===t.key?(e.highlightUp(),t.preventDefault()):"ArrowDown"===t.key?(e.highlightDown(),t.preventDefault()):"Tab"===t.key?e.main.close():"Enter"===t.key&&t.preventDefault()},i.onkeyup=function(t){var i=t.target;if("Enter"===t.key){var n=e.list.querySelector("."+e.main.config.highlighted);n&&n.click(),t.preventDefault()}else"ArrowUp"===t.key||"ArrowDown"===t.key||("Escape"===t.key?e.main.close():e.main.search(i.value));t.preventDefault()},i.onfocus=function(){e.main.open()},t.appendChild(i),{container:t,input:i}},e.prototype.highlightUp=function(){var e=this.list.querySelector("."+this.main.config.highlighted),t=null;if(e)t=e.previousSibling;else{var i=this.list.querySelectorAll("."+this.main.config.option+":not(."+this.main.config.disabled+")");t=i[i.length-1]}if(t&&t.classList.contains(this.main.config.optgroupLabel)&&(t=null),null===t){var s=e.parentNode;s.classList.contains(this.main.config.optgroup)&&s.previousSibling&&(t=s.previousSibling.childNodes[s.previousSibling.childNodes.length-1])}t&&(e&&e.classList.remove(this.main.config.highlighted),t.classList.add(this.main.config.highlighted),n.ensureElementInView(this.list,t))},e.prototype.highlightDown=function(){var e=this.list.querySelector("."+this.main.config.highlighted),t=e?e.nextSibling:this.list.querySelector("."+this.main.config.option+":not(."+this.main.config.disabled+")");if(null===t){var i=e.parentNode;if(i.classList.contains(this.main.config.optgroup)&&i.nextSibling){t=i.nextSibling.querySelector("."+this.main.config.option+":not(."+this.main.config.disabled+")")}}t&&(e&&e.classList.remove(this.main.config.highlighted),t.classList.add(this.main.config.highlighted),n.ensureElementInView(this.list,t))},e.prototype.listDiv=function(){var e=document.createElement("div");return e.classList.add(this.main.config.list),e.onmousewheel=function(t){var i=e.scrollTop,n=e.scrollHeight,s=e.offsetHeight,a="DOMMouseScroll"==t.type?-40*t.detail:t.wheelDelta,o=a>0,l=function(){return t.stopPropagation(),t.preventDefault(),t.returnValue=!1,!1};return!o&&-a>n-s-i?(e.scrollTop=n,l()):o&&a>i?(e.scrollTop=0,l()):void 0},e},e.prototype.options=function(){var e=this.main.data.filtered||this.main.data.data;if(this.list.innerHTML="",0===e.length){var t=document.createElement("div");return t.classList.add(this.main.config.option),t.classList.add(this.main.config.disabled),t.innerHTML=this.main.config.searchText,void this.list.appendChild(t)}for(var i=0;i<e.length;i++)if(e[i].hasOwnProperty("label")){var n=e[i],s=document.createElement("div");s.classList.add(this.main.config.optgroup);var a=document.createElement("div");a.classList.add(this.main.config.optgroupLabel),a.innerHTML=n.label,s.appendChild(a);for(var o=n.options,l=0;l<o.length;l++)s.appendChild(this.option(o[l]));this.list.appendChild(s)}else this.list.appendChild(this.option(e[i]))},e.prototype.option=function(e){var t=this;if(e.placeholder){var i=document.createElement("div");return i.classList.add(this.main.config.option),i.classList.add(this.main.config.hide),i}var s=document.createElement("div");s.classList.add(this.main.config.option);var a=this.main.data.getSelected();return s.dataset.id=e.id,s.innerHTML=e.innerHTML,s.onclick=function(e){if(t.main.beforeOnChange){var i=void 0,n=JSON.parse(JSON.stringify(t.main.data.getObjectFromData(e.target.dataset.id)));n.selected=!0,t.main.config.isMultiple?(i=JSON.parse(JSON.stringify(a)),i.push(n)):i=JSON.parse(JSON.stringify(n));!1!==t.main.beforeOnChange(i)&&t.main.set(e.target.dataset.id,"id")}else t.main.set(e.target.dataset.id,"id")},(e.disabled||a&&n.isValueInArrayOfObjects(a,"id",e.id))&&(s.onclick=null,s.classList.add(this.main.config.disabled)),s},e}();t.default=s},function(e,t,i){"use strict";function n(e){if(!e)throw new Error("Data must be an array of objects");for(var t=0;t<e.length;t++)if(e[t].hasOwnProperty("label")){if(e[t].hasOwnProperty("options"))for(var i=e[t],n=i.options,t=0;t<n.length;t++)s(n[t])}else{var a=e[t];s(a)}}function s(e){if(void 0===e.text)throw new Error("Data object option must have at least have a text value. Check object: "+JSON.stringify(e))}t.__esModule=!0;var a=function(){function e(e){this.contentOpen=!1,this.contentPosition="below",this.main=e.main,this.searchValue="",this.data=[],this.filtered=null,this.parseSelectData(),this.setSelectedFromSelect()}return e.prototype.parseSelectData=function(){this.data=[];for(var e=this.main.select.element,t=e.childNodes,i=0;i<t.length;i++)if("OPTGROUP"===t[i].nodeName){for(var n=t[i],s={label:n.label,options:[]},a=t[i].childNodes,o=0;o<a.length;o++)"OPTION"===a[o].nodeName&&s.options.push(this.pullOptionData(a[o]));this.data.push(s)}else"OPTION"===t[i].nodeName&&this.data.push(this.pullOptionData(t[i]))},e.prototype.pullOptionData=function(e){return{id:!!e.dataset&&e.dataset.id||String(Math.floor(1e8*Math.random())),value:e.value,text:e.text,innerHTML:e.innerHTML,selected:e.selected,disabled:e.disabled,placeholder:e.dataset.placeholder||null,data:e.dataset}},e.prototype.setSelectedFromSelect=function(){var e=this.main.select.element.options;if(this.main.config.isMultiple){for(var t=[],i=0;i<e.length;i++){var n=e[i];n.selected&&t.push(this.getObjectFromData(n.value,"value").id)}this.setSelected(t,"id")}else if(-1!==e.selectedIndex){var n=e[e.selectedIndex],s=n.value;this.setSelected(s,"value")}},e.prototype.setSelected=function(e,t){void 0===t&&(t="id");for(var i=0;i<this.data.length;i++)if(this.data[i].hasOwnProperty("label")){if(this.data[i].hasOwnProperty("options"))for(var n=this.data[i].options,s=0;s<n.length;s++)n[s].selected=this.shouldBeSelected(n[s],e,t)}else this.data[i].selected=this.shouldBeSelected(this.data[i],e,t);this.onDataChange()},e.prototype.shouldBeSelected=function(e,t,i){if(void 0===i&&(i="id"),Array.isArray(t)){for(var n=0;n<t.length;n++)if(String(e[i])===String(t[n]))return!0}else if(String(e[i])===String(t))return!0;return!1},e.prototype.getSelected=function(){for(var e=null,t=[],i=0;i<this.data.length;i++)if(this.data[i].hasOwnProperty("label")){if(this.data[i].hasOwnProperty("options"))for(var n=this.data[i].options,s=0;s<n.length;s++)n[s].selected&&(this.main.config.isMultiple||(e=n[s]),t.push(n[s]))}else this.data[i].selected&&(this.main.config.isMultiple||(e=this.data[i]),t.push(this.data[i]));return this.main.config.isMultiple?t:e},e.prototype.addToSelected=function(e,t){if(void 0===t&&(t="id"),this.main.config.isMultiple){for(var i=[],n=this.getSelected(),s=0;s<n.length;s++)i.push(n[s][t]);i.push(e),this.setSelected(i,t)}},e.prototype.removeFromSelected=function(e,t){if(void 0===t&&(t="id"),this.main.config.isMultiple){for(var i=[],n=this.getSelected(),s=0;s<n.length;s++)String(n[s][t])!==String(e)&&i.push(n[s][t]);this.setSelected(i,t)}},e.prototype.onDataChange=function(){this.main.onChange&&this.main.onChange(JSON.parse(JSON.stringify(this.getSelected())))},e.prototype.getObjectFromData=function(e,t){void 0===t&&(t="id");for(var i=0;i<this.data.length;i++){if(t in this.data[i]&&String(this.data[i][t])===String(e))return this.data[i];if(this.data[i].hasOwnProperty("options"))for(var n=this.data[i],s=0;s<n.options.length;s++)if(String(n.options[s][t])===String(e))return n.options[s]}return null},e.prototype.search=function(e){if(this.searchValue=e,""===e.trim())return void(this.filtered=null);var t=this.data.slice(0);e=e.trim().toLowerCase();var i=t.map(function(t){if(t.hasOwnProperty("options")){var i=t,n=i.options.filter(function(t){return-1!==t.text.toLowerCase().indexOf(e)});if(0!==n.length){var s=Object.assign({},i);return s.options=n,s}}if(t.hasOwnProperty("text")){if(-1!==t.text.toLowerCase().indexOf(e))return t}return null});this.filtered=i.filter(function(e){return e})},e}();t.default=a,t.validateData=n,t.validateOption=s},function(e,t,i){"use strict";t.__esModule=!0;var n=function(){function e(e){this.element=e.select,this.main=e.main,this.element.disabled&&(this.main.config.isEnabled=!1),this.addAttributes(),this.addEventListeners(),this.addMutationObserver()}return e.prototype.setValue=function(){if(this.main.data.getSelected())if(this.main.config.isMultiple)for(var e=this.main.data.getSelected(),t=this.element.options,i=0;i<t.length;i++){var n=t[i];n.selected=!1;for(var s=0;s<e.length;s++)e[s].value===n.value&&(n.selected=!0)}else{var e=this.main.data.getSelected();this.element.value=e?e.value:""}},e.prototype.addAttributes=function(){this.element.tabIndex=-1,this.element.style.display="none"},e.prototype.addEventListeners=function(){var e=this;this.element.addEventListener("change",function(t){e.main.data.setSelectedFromSelect(),e.main.render()})},e.prototype.addMutationObserver=function(){var e=this;this.mutationObserver=new MutationObserver(function(t){e.main.data.parseSelectData(),e.main.data.setSelectedFromSelect(),e.main.render()}),this.observeMutationObserver()},e.prototype.observeMutationObserver=function(){this.mutationObserver.observe(this.element,{attributes:!0,childList:!0,characterData:!0})},e.prototype.disconnectMutationObserver=function(){this.mutationObserver.disconnect()},e.prototype.create=function(e){this.element.innerHTML="";for(var t=0;t<e.length;t++)if(e[t].hasOwnProperty("options")){var i=e[t],n=document.createElement("optgroup");n.label=i.label;for(var s=0;s<i.options.length;s++)n.appendChild(this.createOption(i.options[s]));this.element.appendChild(n)}else this.element.appendChild(this.createOption(e[t]))},e.prototype.createOption=function(e){var t=document.createElement("option");return t.value=e.value||e.text,t.innerHTML=e.innerHTML||e.text,e.selected&&(t.selected=e.selected),e.disabled&&(t.disabled=!0),e.placeholder&&t.setAttribute("data-placeholder","true"),e.data&&"object"==typeof e.data&&Object.keys(e.data).forEach(function(i){t.setAttribute("data-"+i,e.data[i])}),t},e}();t.default=n},function(e,t,i){"use strict";t.__esModule=!0,i(1);var n=i(2),s=i(0),a=i(5),o=i(4),l=i(3),r=function(){function e(e){var t=this;this.beforeOnChange=null,this.onChange=null,this.validate(e);var i="string"==typeof e.select?document.querySelector(e.select):e.select;this.config=new n.default({select:i,showSearch:e.showSearch,searchText:e.searchText,placeholderText:e.placeholder,isEnabled:e.isEnabled}),this.select=new a.default({select:i,main:this}),this.data=new o.default({main:this}),this.slim=new l.default({main:this}),this.select.element.parentNode.insertBefore(this.slim.container,this.select.element.nextSibling),this.render(),document.addEventListener("click",function(e){s.hasClassInTree(e.target,t.config.id)||t.close()}),window.addEventListener("scroll",s.debounce(function(e){t.data.contentOpen&&("above"===s.putContent(t.slim.content,t.data.contentPosition,t.data.contentOpen)?t.moveContentAbove():t.moveContentBelow())}),!1),e.beforeOnChange&&(this.beforeOnChange=e.beforeOnChange),e.onChange&&(this.onChange=e.onChange)}return e.prototype.validate=function(e){var t="string"==typeof e.select?document.querySelector(e.select):e.select;if(!t)throw new Error("Could not find select element");if("SELECT"!==t.tagName)throw new Error("Element isnt of type select")},e.prototype.set=function(e,t,i){void 0===t&&(t="value"),void 0===i&&(i=!0),this.config.isMultiple&&!Array.isArray(e)?this.data.addToSelected(e,t):this.data.setSelected(e,t),this.render(),this.select.setValue(),i&&this.close()},e.prototype.setData=function(e){o.validateData(e);var t=JSON.parse(JSON.stringify(e));this.select.create(t),this.data.parseSelectData(),this.data.setSelectedFromSelect(),this.render()},e.prototype.open=function(){this.slim.search.input.focus(),this.data.contentOpen||(this.config.isMultiple?this.slim.multiSelected.plus.classList.add("ss-cross"):(this.slim.singleSelected.arrowIcon.arrow.classList.remove("arrow-down"),this.slim.singleSelected.arrowIcon.arrow.classList.add("arrow-up")),this.slim[this.config.isMultiple?"multiSelected":"singleSelected"].container.classList.add("above"===this.data.contentPosition?this.config.openAbove:this.config.openBelow),this.slim.content.classList.add(this.config.open),"above"===s.putContent(this.slim.content,this.data.contentPosition,this.data.contentOpen)?this.moveContentAbove():this.moveContentBelow(),this.data.contentOpen=!0)},e.prototype.close=function(){this.data.contentOpen&&(this.slim.search.input.blur(),this.config.isMultiple?(this.slim.multiSelected.container.classList.remove(this.config.openAbove),this.slim.multiSelected.container.classList.remove(this.config.openBelow),this.slim.multiSelected.plus.classList.remove("ss-cross")):(this.slim.singleSelected.container.classList.remove(this.config.openAbove),this.slim.singleSelected.container.classList.remove(this.config.openBelow),this.slim.singleSelected.arrowIcon.arrow.classList.add("arrow-down"),this.slim.singleSelected.arrowIcon.arrow.classList.remove("arrow-up")),this.slim.content.classList.remove(this.config.open),this.data.contentOpen=!1,this.search(""))},e.prototype.moveContentAbove=function(){var e=this.config.isMultiple?this.slim.multiSelected.container.offsetHeight:this.slim.singleSelected.container.offsetHeight,t=this.slim.content.offsetHeight,i=e+t-1;this.slim.content.style.margin="-"+i+"px 0 0 0",this.slim.content.style["transform-origin"]="center bottom",this.data.contentPosition="above",this.data.contentOpen&&(this.slim[this.config.isMultiple?"multiSelected":"singleSelected"].container.classList.remove(this.config.openBelow),this.slim[this.config.isMultiple?"multiSelected":"singleSelected"].container.classList.add(this.config.openAbove))},e.prototype.moveContentBelow=function(){this.slim.content.removeAttribute("style"),this.data.contentPosition="below",this.data.contentOpen&&(this.slim[this.config.isMultiple?"multiSelected":"singleSelected"].container.classList.remove(this.config.openAbove),this.slim[this.config.isMultiple?"multiSelected":"singleSelected"].container.classList.add(this.config.openBelow))},e.prototype.enable=function(){this.config.isEnabled=!0,this.config.isMultiple?this.slim.multiSelected.container.classList.remove(this.config.disabled):this.slim.singleSelected.container.classList.remove(this.config.disabled),this.select.disconnectMutationObserver(),this.select.element.disabled=!1,this.select.observeMutationObserver()},e.prototype.disable=function(){this.config.isEnabled=!1,this.config.isMultiple?this.slim.multiSelected.container.classList.add(this.config.disabled):this.slim.singleSelected.container.classList.add(this.config.disabled),this.select.disconnectMutationObserver(),this.select.element.disabled=!0,this.select.observeMutationObserver()},e.prototype.search=function(e){this.data.searchValue!==e&&(this.slim.search.input.value=e,this.data.search(e),this.render())},e.prototype.render=function(){this.config.isMultiple?this.slim.values():this.slim.placeholder(),this.slim.options()},e.prototype.destroy=function(){this.select.element.style.display="inline-block",this.slim.container.parentElement.removeChild(this.slim.container)},e}();t.default=r,e.exports=r}])});
</script>
<script>
//^^/src/init.js$$
const sizeSuffix = function(size) {
if (size < 1000) { return size + 'bp'; } else if (size < 1000000) { return (size / 1000).toFixed(2) + 'Kb'; } else if (size < 1000000000) { return (size / 1000000).toFixed(2) + 'Mb'; } else { return (size / 1000000000).toFixed(2) + 'Gb'; }
}
let numPrefixObj = { 1: 'Monomer', 2: 'Dimer', 3: 'Trimer', 4: 'Tetramer', 5: 'Pentamer', 6: 'Hexamer', 7: 'Septamer', 8: 'Octamer', 9: 'Enneamer', 10: 'Decamer' }
let plotInfo = data['info']['plotInfo'];
let minLength = parseInt(data['info']['minLength']);
let minUnits = parseInt(data['info']['minUnits']);
let kmerLengths = _.uniq(_.map(Object.keys(plotInfo['len']), function(o) { return o.length; })).sort();
let kMers = _.map(kmerLengths, function(o) { if (_.map(Object.keys(numPrefixObj), parseFloat).indexOf(o) != -1) { return numPrefixObj[o] } else { return o + '-kmer' } });
let kmerObj = {};
for (let k in kMers) { kmerObj[kmerLengths[k]] = kMers[k]; }
let repeatSet = {};
for (let k in kMers) { repeatSet[kMers[k]] = []; }
for (let repeat in plotInfo['len']) { repeatSet[kmerObj[repeat.length]].push(repeat); }
for (let group in repeatSet) { repeatSet[group].sort(); }
let basicInfoKeys = ['name', 'genomeSize', 'GC', 'numSeq', 'numRepClass', 'totalRepBases', 'totalRepFreq', 'percentGenomeCovered', 'repDensityByFreq', 'repDensityByBases'];
for (let k in basicInfoKeys) {
k = basicInfoKeys[k];
let spanElement = document.getElementById(k);
if (k == 'totalRepBases' || k == 'genomeSize') { spanElement.innerHTML = sizeSuffix(data['info'][k]); } else { spanElement.innerHTML = data['info'][k]; }
spanElement.setAttribute('title', data['info'][k]);
}
const populateTable = function(id, data) {
const tableBodyElement = document.querySelector("#" + id + "> tbody");
const keys = ['seq', 'start', 'end', 'repClass', 'repLength', 'repOri', 'repUnit', 'actualRep']
const keyObj = { seq: "Sequence id", start: "Start", end: "End", repClass: "Repeat class", repLength: "Length", repOri: "Strand", repUnit: "Repeat units", actualRep: "Actual repeat" }
for (let o in data) {
let obj = data[o];
let rowElement = document.createElement("tr");
for (let key in keys) {
key = keys[key];
let cellElement = document.createElement("td");
cellElement.setAttribute('data-label', keyObj[key]);
cellElement.setAttribute('title', obj[key]);
cellElement.innerHTML = obj[key];
rowElement.appendChild(cellElement)
}
tableBodyElement.appendChild(rowElement);
}
}
populateTable('most-repeat-units-table', data['info']['mostRepeatUnits']);
populateTable('longest-repeats-table', data['info']['longestRepeats']);
const addOptionsToMultiSelect = function(id) {
let multiSelect = document.getElementById(id);
let selectAll = document.createElement("option");
selectAll.setAttribute("value", "select-all");
selectAll.setAttribute("id", "select-all");
selectAll.innerHTML = "Select All";
multiSelect.appendChild(selectAll);
for (let kmer in kMers) {
kmer = kMers[kmer];
let kmerOptGroup = document.createElement("optgroup");
kmerOptGroup.setAttribute("label", kmer);
let selectAll = document.createElement("option");
selectAll.setAttribute("value", `select-all-${kmer}`)
selectAll.innerHTML = 'Select All ' + kmer;
kmerOptGroup.appendChild(selectAll);
for (let repeat in repeatSet[kmer]) {
repeat = repeatSet[kmer][repeat];
let repeatOpt = document.createElement("option");
repeatOpt.setAttribute("value", repeat);
repeatOpt.innerHTML = repeat;
kmerOptGroup.appendChild(repeatOpt);
}
multiSelect.appendChild(kmerOptGroup);
}
}
addOptionsToMultiSelect('bar-repeats-sel');
addOptionsToMultiSelect('pie-repeats-sel');
addOptionsToMultiSelect('line-repeats-sel');
</script>
<script>
//^^/src/barPlot.js$$
/*-- BAR PLOT -------------------------------------------------------------------------------*/
const barDatum = function(data, n, s, repeats, rs) {
let datum = []
let orderedRepeats = _.flatMap(repeatSet, function(d) { return d });
if (repeats) {
for (let d in orderedRepeats) { d = orderedRepeats[d]; if (repeats.indexOf(d) > -1) { datum.push([d, _.sum(data[d])]); } }
if (rs == 1) {
datum = _.sortBy(datum, function(d) { return d[1]; });
datum = datum.reverse();
}
} else if (n) {
for (let d in data) { datum.push([d, _.sum(data[d])]) };
datum = _.sortBy(datum, function(d) { return d[1]; });
if (!(s)) { datum = datum.reverse(); }
datum = datum.slice(0, n);
}
return datum;
}
const barPlot = function(selectionType, repeats) {
let plotData;
if (selectionType == 'sort') {
const numBars = document.getElementById('bar-num').value;
const sort = document.getElementById('bar-select').selectedIndex;
plotData = barDatum(plotInfo['len'], numBars, sort);
} else if (selectionType == 'repeat') {
const barSortRadios = document.getElementsByName('bar-sort');
let repeatSort;
for (let i in barSortRadios) {
let radio = barSortRadios[i];
if (radio.tagName == 'INPUT') { if (radio.checked) { repeatSort = radio.value; } }
}
plotData = barDatum(plotInfo['len'], 0, 0, repeats, repeatSort);
}
Highcharts.chart('bar-plot-svg', {
chart: { type: 'column', marginTop: 40, marginLeft: 100 },
title: { text: null },
xAxis: { type: 'category', title: { text: 'Repeat Class' }, labels: { rotation: -45, style: { fontSize: '12px', fontFamily: 'Verdana, sans-serif' } } },
yAxis: { min: 0, title: { text: 'Frequency' } },
legend: { enabled: false },
tooltip: { pointFormat: 'Frequency: <b>{point.y}</b>' },
series: [{ name: 'Frequency', data: plotData, dataLabels: { enabled: false, } }]
});
}
document.getElementById('bar-num').oninput = function() { barPlot('sort') };
document.getElementById('bar-select').onchange = function() { barPlot('sort') };
let barSetValues = [];
let barPlotRepeats;
let barRepeatSelect = new SlimSelect({ select: "#bar-repeats-sel", placeholder: 'Select Repeats', });
barRepeatSelect.beforeOnChange = function(info) {
if (info.length != 0) {
let allValues = _.map(info, 'value');
barSetValues = allValues;
let lastValue = info[info.length - 1].value;
if (lastValue == 'select-all') {
for (let k in repeatSet) {
barSetValues = barSetValues.concat([`select-all-${k}`])
barSetValues = barSetValues.concat(repeatSet[k]);
barSetValues = _.uniq(barSetValues);
barRepeatSelect.set([]);
barRepeatSelect.set(barSetValues);
}
} else if (lastValue.length > 10 && lastValue.slice(0, 10) == 'select-all') {
let kmer = lastValue.slice(11, lastValue.length);
barSetValues = allValues.concat(repeatSet[kmer]);
barSetValues = _.uniq(barSetValues);
barRepeatSelect.set([]);
barRepeatSelect.set(barSetValues);
}
barPlotRepeats = _.filter(barSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
barPlot('repeat', barPlotRepeats);
}
}
barRepeatSelect.onChange = function(info) {
let currentValues = _.map(info, 'value');
if (currentValues.length == 0 && barSetValues.length - currentValues.length == 1 && barSetValues[0].slice(0, 10) == 'select-all') {
// pass;
} else if (barSetValues.length - currentValues.length == 1) {
let removedValue = (_.difference(barSetValues, currentValues))[0];
if (removedValue == 'select-all') {
currentValues = [];
barRepeatSelect.set([]);
barRepeatSelect.set(currentValues);
barSetValues = currentValues;
barPlotRepeats = _.filter(barSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
barPlot('repeat', barPlotRepeats);
} else if (removedValue.length > 10 && removedValue.slice(0, 10) == 'select-all') {
let kmer = removedValue.slice(11, removedValue.length);
let tempCurrentValues = _.difference(currentValues, repeatSet[kmer]);
currentValues = tempCurrentValues;
barSetValues = currentValues;
if (_.intersection(repeatSet[kmer], barPlotRepeats).length > 0) {
barRepeatSelect.set([]);
barRepeatSelect.set(currentValues);
barPlotRepeats = _.filter(barSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
barPlot('repeat', barPlotRepeats);
}
} else {
barSetValues = currentValues;
barPlotRepeats = _.filter(barSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
barPlot('repeat', barPlotRepeats);
}
} else if (currentValues.length == 0) {
//pass;
}
}
const barSortRadios = document.getElementsByName('bar-sort');
for (let i in barSortRadios) {
let radio = barSortRadios[i];
if (radio.tagName == 'INPUT') {
radio.onchange = function() { barPlot('repeat', barPlotRepeats); }
}
}
let initial = 1;
const placeholderBarPlot = function() {
if (initial) {
barPlot('sort');
initial = 0
}
}
</script>
<script>
//^^/src/piePlot.js$$
/*-- PIE PLOT -------------------------------------------------------------------------------*/
const pieDatum = function(data, type, repeats, group) {
let datum;
let pieData = {};
for (let d in data) {
if (repeats.indexOf(d) > -1) {
pieData[d] = data[d];
}
}
let totalFreq = 0;
let totalBases = 0;
for (let i in pieData) {
totalFreq += _.sum(pieData[i]);
totalBases += (_.sum(pieData[i])) * (i.length);
}
if (group == 1) {
let kmerDataObj = {};
for (let k in kMers) { kmerDataObj[kMers[k]] = 0; }
datum = _.map(Object.keys(pieData), function(d) {
if (type == 'Frequency') { kmerDataObj[kmerObj[d.length]] += _.sum(pieData[d]); } else { kmerDataObj[kmerObj[d.length]] += _.sum(pieData[d]) * d.length; }
});
datum = [];
for (let k in kmerDataObj) { datum.push({ name: k, y: kmerDataObj[k] }); }
} else {
datum = _.map(Object.keys(pieData), function(d) {
let point;
if (type == 'Frequency') { point = { name: d, y: _.sum(pieData[d]) } } else { point = { name: d, y: _.sum(pieData[d]) * d.length }; }
return point;
});
}
// console.log(datum)
return datum
}
const piePlot = function(repeats) {
const dataTypeRadios = document.getElementsByName('data-type');
console.log(dataTypeRadios)
let dataType;
for (let i in dataTypeRadios) {
let radio = dataTypeRadios[i];
if (radio.tagName == 'INPUT') {
if (radio.checked) {
dataType = radio.value;
}
}
}
console.log(dataType);
const lenGroupRadios = document.getElementsByName('len-group');
let lenGroup;
for (let i in lenGroupRadios) {
let radio = lenGroupRadios[i];
if (radio.tagName == 'INPUT') {
if (radio.checked) {
lenGroup = radio.value;
}
}
}
let plotData = pieDatum(plotInfo['len'], dataType, repeats, lenGroup);
Highcharts.chart('pie-plot-svg', {
chart: {
plotBackgroundColor: null,
plotBorderWidth: null,
plotShadow: false,
type: 'pie',
marginTop: 40
},
title: {
text: null
},
tooltip: {
pointFormat: '{series.name}: <b>{point.percentage:.1f}%</b>'
},
plotOptions: {
pie: {
allowPointSelect: true,
cursor: 'pointer',
dataLabels: {
enabled: false
},
showInLegend: true
}
},
series: [{
name: 'Frequency',
colorByPoint: true,
data: plotData
}]
});
}
let pieSetValues = [];
let piePlotRepeats = [];
let pieRepeatSelect = new SlimSelect({
select: "#pie-repeats-sel",
placeholder: 'Select Repeats',
});
pieRepeatSelect.beforeOnChange = function(info) {
if (info.length != 0) {
let allValues = _.map(info, 'value')
pieSetValues = allValues;
let lastValue = info[info.length - 1].value
if (lastValue == 'select-all') {
for (let k in repeatSet) {
pieSetValues = pieSetValues.concat([`select-all-${k}`])
pieSetValues = pieSetValues.concat(repeatSet[k]);
pieSetValues = _.uniq(pieSetValues);
pieRepeatSelect.set([]);
pieRepeatSelect.set(pieSetValues);
}
} else if (lastValue.slice(0, 10) == 'select-all') {
let kmer = lastValue.slice(11, lastValue.length)
pieSetValues = allValues.concat(repeatSet[kmer]);
pieSetValues = _.uniq(pieSetValues);
pieRepeatSelect.set([]);
pieRepeatSelect.set(pieSetValues);
}
piePlotRepeats = _.filter(pieSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
piePlot(piePlotRepeats)
}
}
pieRepeatSelect.onChange = function(info) {
let currentValues = _.map(info, 'value');
if (currentValues.length == 0 && pieSetValues.length - currentValues.length == 1 && pieSetValues[0].slice(0, 10) == 'select-all') {
//pass
} else if (pieSetValues.length - currentValues.length == 1) {
let removedValue = (_.difference(pieSetValues, currentValues))[0];
if (removedValue == 'select-all') {
currentValues = [];
pieRepeatSelect.set([]);
pieRepeatSelect.set(currentValues);
pieSetValues = currentValues;
piePlotRepeats = _.filter(pieSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
piePlot('repeat', piePlotRepeats);
} else if (removedValue.length > 10 && removedValue.slice(0, 10) == 'select-all') {
let kmer = removedValue.slice(11, removedValue.length);
let tempCurrentValues = _.difference(currentValues, repeatSet[kmer]);
currentValues = tempCurrentValues;
pieSetValues = currentValues;
if (_.intersection(repeatSet[kmer], piePlotRepeats).length > 0) {
pieRepeatSelect.set([]);
pieRepeatSelect.set(currentValues);
piePlotRepeats = _.filter(pieSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
piePlot(piePlotRepeats);
}
} else {
pieSetValues = currentValues;
piePlotRepeats = _.filter(pieSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
piePlot(piePlotRepeats);
}
} else if (currentValues.length == 0) {
//pass;
}
}
const dataTypeRadios = document.getElementsByName('data-type');
for (let i in dataTypeRadios) {
let radio = dataTypeRadios[i];
if (radio.tagName == 'INPUT') {
radio.onchange = function() { piePlot(piePlotRepeats); }
}
}
const lenGroupRadios = document.getElementsByName('len-group');
for (let i in lenGroupRadios) {
let radio = lenGroupRadios[i];
if (radio.tagName == 'INPUT') {
radio.onchange = function() { piePlot(piePlotRepeats); }
}
}
</script>
<script>
//^^/src/linePlot.js$$
/*-- LINE PLOT ------------------------------------------------------------------------------*/
const lineDatum = function(data, xdata, repeats, minL, maxL) {
let datum = [];
if (xdata == 0) {
for (let r in repeats) {
let repeat = repeats[r];
datum.push({
name: repeat,
data: data['len'][repeat].slice(minL - minLength, maxL - minLength + 1)
})
}
} else {
for (let r in repeats) {
let repeat = repeats[r];
datum.push({
name: repeat,
data: data['unit'][repeat].slice(minL - minUnits, maxL - minUnits + 1)
})
}
}
return datum
}
let a = _.flatMap(plotInfo['len'], function(d) { return d.length + minLength - 1; });
document.getElementById('max-linex').value = _.max(a);
const linePlot = function(repeats) {
const maxL = parseInt(document.getElementById('max-linex').value);
const minL = parseInt(document.getElementById('min-linex').value);
const xdata = document.getElementById('line-select').selectedIndex;
let xLabel;
if (xdata == 0) { xLabel = 'Sequence length(bp)'; } else { xLabel = 'Repeat Units'; }
plotData = lineDatum(plotInfo, xdata, repeats, minL, maxL);
Highcharts.chart('line-plot-svg', {
chart: {
marginTop: 40,
marginLeft: 100
},
title: {
text: null
},
yAxis: {
title: {
text: 'Frequency'
}
},
xAxis: {
title: {
text: xLabel
},
labels: {
format: '{value:.0f}'
},
tickInterval: 1
},
legend: {
layout: 'vertical',
align: 'right',
verticalAlign: 'middle'
},
plotOptions: {
series: {
pointStart: parseInt(minL)
}
},
series: plotData
});
}
let lineSetValues = [];
let linePlotRepeats = [];
let lineRepeatSelect = new SlimSelect({
select: "#line-repeats-sel",
placeholder: 'Select Repeats',
});
lineRepeatSelect.beforeOnChange = function(info) {
if (info.length != 0) {
let allValues = _.map(info, 'value')
lineSetValues = allValues;
let lastValue = info[info.length - 1].value
if (lastValue == 'select-all') {
for (let k in repeatSet) {
lineSetValues = lineSetValues.concat([`select-all-${k}`])
lineSetValues = lineSetValues.concat(repeatSet[k]);
lineSetValues = _.uniq(lineSetValues);
lineRepeatSelect.set([]);
lineRepeatSelect.set(lineSetValues);
}
} else if (lastValue.length > 10 && lastValue.slice(0, 10) == 'select-all') {
let kmer = lastValue.slice(11, lastValue.length)
lineSetValues = allValues.concat(repeatSet[kmer]);
lineSetValues = _.uniq(lineSetValues);
lineRepeatSelect.set([]);
lineRepeatSelect.set(lineSetValues);
}
linePlotRepeats = _.filter(lineSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
linePlot(linePlotRepeats)
}
}
lineRepeatSelect.onChange = function(info) {
let currentValues = _.map(info, 'value');
if (currentValues.length == 0 && lineSetValues.length - currentValues.length == 1 && lineSetValues[0].slice(0, 10) == 'select-all') {
//pass
} else if (lineSetValues.length - currentValues.length == 1) {
let removedValue = (_.difference(lineSetValues, currentValues))[0];
if (removedValue == 'select-all') {
currentValues = [];
lineRepeatSelect.set([]);
lineRepeatSelect.set(currentValues);
lineSetValues = currentValues;
linePlotRepeats = [];
linePlot(linePlotRepeats);
} else if (removedValue.length > 10 && removedValue.slice(0, 10) == 'select-all') {
let kmer = removedValue.slice(11, removedValue.length);
let tempCurrentValues = _.difference(currentValues, repeatSet[kmer]);
currentValues = tempCurrentValues;
lineSetValues = currentValues;
if (_.intersection(repeatSet[kmer], linePlotRepeats).length > 0) {
lineRepeatSelect.set([]);
lineRepeatSelect.set(currentValues);
linePlotRepeats = _.filter(lineSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
linePlot(linePlotRepeats);
}
} else {
lineSetValues = currentValues;
linePlotRepeats = _.filter(lineSetValues, function(d) {
return d.slice(0, 10) != 'select-all';
});
linePlot(linePlotRepeats);
}
} else if (currentValues.length == 0) {
//pass;
}
}
document.getElementById('min-linex').oninput = function() { linePlot(linePlotRepeats) };
document.getElementById('max-linex').oninput = function() { linePlot(linePlotRepeats) };
document.getElementById('line-select').onchange = function() {
if (this.selectedIndex == 0) {
document.getElementById('min-linex').value = minLength
} else {
document.getElementById('min-linex').value = minUnits
}
linePlot(linePlotRepeats);
};
</script>
</html>