from sympy import Symbol, Matrix a = Symbol("a") A = Matrix([ [-180*a - 305, 315*a + 526, -90*a - 131, 1035*a + 1754, 1530*a + 2587], [-190*a - 360, 316*a + 587, -66*a - 98, 1084*a + 2041, 1600*a + 3006], [-115*a - 217, 193*a + 356, -43*a - 63, 657*a + 1232, 970*a + 1815], [ 222*a + 444, -372*a - 730, 82*a + 136, -1268*a - 2520, -1872*a - 3716], [-139*a - 275, 235*a + 456, -55*a - 91, 795*a + 1564, 1174*a + 2307]])