@prefix : <file:///ERROR/EMPTY/PREFIX/BANNED/> .
@prefix AIBSTL: <http://api.brain-map.org/api/v2/data/TransgenicLine/> .
@prefix CHEBI: <http://purl.obolibrary.org/obo/CHEBI_> .
@prefix ilxtr: <http://uri.interlex.org/tgbugs/uris/readable/> .
@prefix JAX: <http://jaxmice.jax.org/strain/> .
@prefix MMRRC: <http://www.mmrrc.org/catalog/getSDS.jsp?mmrrc_id=> .
@prefix NCBIGene: <http://www.ncbi.nlm.nih.gov/gene/> .
@prefix NIFEXT: <http://uri.neuinfo.org/nif/nifstd/nifext_> .
@prefix NIFRID: <http://uri.neuinfo.org/nif/nifstd/readable/> .
@prefix NLXMOL: <http://uri.neuinfo.org/nif/nifstd/nlx_mol_> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix PR: <http://purl.obolibrary.org/obo/PR_> .
@prefix PTHR: <http://www.pantherdb.org/panther/family.do?clsAccession=PTHR> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix SAO: <http://uri.neuinfo.org/nif/nifstd/sao> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix TEMPIND: <http://uri.interlex.org/temp/uris/phenotype-indicators/> .

<https://raw.githubusercontent.com/SciCrunch/NIF-Ontology/neurons/ttl/phenotype-indicators.ttl> a owl:Ontology ;
    rdfs:label "Phenotype indicators" ;
    owl:versionInfo "2023-04-27" .

### Classes

ilxtr:PhenotypeIndicator a owl:Class ;
    rdfs:label "phenotype indicator" .

TEMPIND:ACh a owl:Class ;
    rdfs:label "ACh (indicator)" ;
    NIFRID:synonym "Acetylcholine",
        "ChAT",
        "Choline O-acetyltransferase",
        "Slc18a3",
        "VAChT",
        "Vesicular acetylcholine transporter" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "ACh" .

TEMPIND:Adm a owl:Class ;
    rdfs:label "Adm (indicator)" ;
    NIFRID:synonym "adrenomedulin" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Adm" .

TEMPIND:Avp a owl:Class ;
    rdfs:label "Avp (indicator)" ;
    NIFRID:synonym "vasopressin" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Avp" .

TEMPIND:Calb a owl:Class ;
    rdfs:label "Calb (indicator)" ;
    NIFRID:synonym "Calb1",
        "Calbindin",
        "calbindin 1",
        "CB" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Calb" .

TEMPIND:Calb2 a owl:Class ;
    rdfs:label "Calb2 (indicator)" ;
    NIFRID:synonym "Calbindin 2",
        "calretinin",
        "CR" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Calb2" .

TEMPIND:Calca a owl:Class ;
    rdfs:label "Calca (indicator)" ;
    NIFRID:synonym "calcitonin gene-related peptide 1" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Calca" .

TEMPIND:Cck a owl:Class ;
    rdfs:label "Cck (indicator)" ;
    NIFRID:synonym "cholecystokinin" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Cck" .

TEMPIND:Cckbr a owl:Class ;
    rdfs:label "Cckbr (indicator)" ;
    NIFRID:synonym "cholecystokinin B receptor" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Cckbr" .

TEMPIND:Chrm2 a owl:Class ;
    rdfs:label "Chrm2 (indicator)" ;
    NIFRID:synonym "cholinergic receptor",
        "muscarinic 2" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Chrm2" .

TEMPIND:Cnr1 a owl:Class ;
    rdfs:label "Cnr1 (indicator)" ;
    NIFRID:synonym "brain-type cannabinoid receptor" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Cnr1" .

TEMPIND:Cort a owl:Class ;
    rdfs:label "Cort (indicator)" ;
    NIFRID:synonym "cortistatin" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Cort" .

TEMPIND:CreDependentProteinFluorescingInSpectrumRed a owl:Class ;
    rdfs:label "CreDependentProteinFluorescingInSpectrumRed (indicator)" ;
    NIFRID:synonym "Ai14",
        "Ai14(RCL-tdT)",
        "Ai14(RCL-tdT)-D",
        "Ai14D" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "CreRFP" .

TEMPIND:CreFlpDependentProteinFluorescingInSpectrumRed a owl:Class ;
    rdfs:label "CreFlpDependentProteinFluorescingInSpectrumRed (indicator)" ;
    NIFRID:synonym "Ai65",
        "Ai65(RCFL-tdT)",
        "Ai65(RCFL-tdT)-D",
        "Ai65D" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "CreFlpRFP" .

TEMPIND:Crh a owl:Class ;
    rdfs:label "Crh (indicator)" ;
    NIFRID:synonym "corticoliberin",
        "corticotropin releasing factor",
        "corticotropin releasing hormone",
        "CRF" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Crh" .

TEMPIND:Drd1 a owl:Class ;
    rdfs:label "Drd1 (indicator)" ;
    NIFRID:synonym "D1 receptor",
        "dopamine receptor D1" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Drd1" .

TEMPIND:Drd2 a owl:Class ;
    rdfs:label "Drd2 (indicator)" ;
    NIFRID:synonym "D2 receptor",
        "dopamine receptor D2" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Drd2" .

TEMPIND:Edn3 a owl:Class ;
    rdfs:label "Edn3 (indicator)" ;
    NIFRID:synonym "endothelin 3" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Edn3" .

TEMPIND:GABA a owl:Class ;
    rdfs:label "GABA (indicator)" ;
    NIFRID:synonym "Gad2",
        "gamma-Aminobutyric acid",
        "Glutamate decarboxylase 2",
        "Slc32a1",
        "Vesicular inhibitory amino acid transporter",
        "VGAT" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "GABA" .

TEMPIND:GABAR a owl:Class ;
    rdfs:label "GABAR (indicator)" ;
    NIFRID:synonym "GABA receptor" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "GABAR" .

TEMPIND:GluR a owl:Class ;
    rdfs:label "GluR (indicator)" ;
    NIFRID:synonym "Glutamate receptor" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "GluR" .

TEMPIND:Glutamate a owl:Class ;
    rdfs:label "Glutamate (indicator)" ;
    NIFRID:synonym "GLU",
        "Glu",
        "L-Glutamate",
        "Slc17a6",
        "Vesicular glutamate transporter 2",
        "VGluT2" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Glu" .

TEMPIND:Htr3a a owl:Class ;
    rdfs:label "Htr3a (indicator)" ;
    NIFRID:synonym "5-hydroxytryptamine receptor 3A",
        "serotonin receptor 3A" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Htr3a" .

TEMPIND:Igf1 a owl:Class ;
    rdfs:label "Igf1 (indicator)" ;
    NIFRID:synonym "insulin-like growth factor I" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Igf1" .

TEMPIND:Nos1 a owl:Class ;
    rdfs:label "Nos1 (indicator)" ;
    NIFRID:synonym "neuronal nitric oxide synthase" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Nos1" .

TEMPIND:Npy a owl:Class ;
    rdfs:label "Npy (indicator)" ;
    NIFRID:synonym "Neuropeptide Y" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Npy" .

TEMPIND:Oxtr a owl:Class ;
    rdfs:label "Oxtr (indicator)" ;
    NIFRID:synonym "Oxytocin receptor" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Oxtr" .

TEMPIND:Penk a owl:Class ;
    rdfs:label "Penk (indicator)" ;
    NIFRID:synonym "ENK",
        "enkephalin",
        "preproenkephalin" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Penk" .

TEMPIND:ProteinFluorescingInSpectrumRed a owl:Class ;
    rdfs:label "ProteinFluorescingInSpectrumRed (indicator)" ;
    NIFRID:synonym "DsRed",
        "mCherry",
        "RFP",
        "tdT",
        "tdTomato" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "RFP" .

TEMPIND:Pvalb a owl:Class ;
    rdfs:label "parvalbumin (indicator)" ;
    NIFRID:synonym "parvalbumin",
        "PV",
        "Pvalb" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "PV" .

TEMPIND:Serotonin a owl:Class ;
    rdfs:label "Serotonin (indicator)" ;
    NIFRID:synonym "5-HT",
        "5-hydroxytryptamine",
        "SERT",
        "Slc6a4",
        "Sodium-dependent serotonin transporter" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "5-HT" .

TEMPIND:Sst a owl:Class ;
    rdfs:label "somatostatin (indicator)" ;
    NIFRID:synonym "SOM",
        "somatostatin",
        "Sst" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Sst" .

TEMPIND:TH a owl:Class ;
    rdfs:label "TH (indicator)" ;
    NIFRID:synonym "TH",
        "Th",
        "Tyrosine 3-monooxygenase",
        "Tyrosine hydroxylase" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "TH" .

TEMPIND:VIP a owl:Class ;
    rdfs:label "VIP (indicator)" ;
    NIFRID:synonym "synonym \"vasoactive intestinal polypeptide\"" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "VIP" .

TEMPIND:Vipr1 a owl:Class ;
    rdfs:label "Vipr1 (indicator)" ;
    NIFRID:synonym "vasoactive intestinal peptide receptor 1" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Vipr1" .

TEMPIND:Vipr2 a owl:Class ;
    rdfs:label "Vipr2 (indicator)" ;
    NIFRID:synonym "vasoactive intestinal peptide receptor 2" ;
    rdfs:subClassOf ilxtr:PhenotypeIndicator ;
    skos:hiddenLabel "Vipr2" .

### Annotations

AIBSTL:301021674 rdfs:subClassOf TEMPIND:Oxtr .

AIBSTL:543338518 rdfs:subClassOf TEMPIND:Vipr2 .

CHEBI:9937 rdfs:subClassOf TEMPIND:Avp .

CHEBI:15355 rdfs:subClassOf TEMPIND:ACh .

CHEBI:16015 rdfs:subClassOf TEMPIND:Glutamate .

CHEBI:16865 rdfs:subClassOf TEMPIND:GABA .

CHEBI:28790 rdfs:subClassOf TEMPIND:Serotonin .

CHEBI:64628 rdfs:subClassOf TEMPIND:Sst .

ilxtr:CCK-cre rdfs:subClassOf TEMPIND:Cck .

ilxtr:GABAReceptor rdfs:subClassOf TEMPIND:GABAR .

ilxtr:glutamateReceptor rdfs:subClassOf TEMPIND:GluR .

ilxtr:NOS1-creER rdfs:subClassOf TEMPIND:Nos1 .

ilxtr:PV-cre rdfs:subClassOf TEMPIND:Pvalb .

ilxtr:Pvalb rdfs:subClassOf TEMPIND:Pvalb .

ilxtr:SST-flp rdfs:subClassOf TEMPIND:Sst .

ilxtr:VIP-flp rdfs:subClassOf TEMPIND:VIP .

JAX:006410 rdfs:subClassOf TEMPIND:ACh .

JAX:007914 rdfs:subClassOf TEMPIND:CreDependentProteinFluorescingInSpectrumRed .

JAX:008069 rdfs:subClassOf TEMPIND:Pvalb .

JAX:010802 rdfs:subClassOf TEMPIND:GABA .

JAX:010908 rdfs:subClassOf TEMPIND:VIP .

JAX:012706 rdfs:subClassOf TEMPIND:Cck .

JAX:013044 rdfs:subClassOf TEMPIND:Sst .

JAX:013730 rdfs:subClassOf TEMPIND:Calb2 .

JAX:014541 rdfs:subClassOf TEMPIND:Nos1 .

JAX:017320 rdfs:subClassOf TEMPIND:Pvalb .

JAX:021189 rdfs:subClassOf TEMPIND:Pvalb .

JAX:021190 rdfs:subClassOf TEMPIND:Pvalb .

JAX:021875 rdfs:subClassOf TEMPIND:CreFlpDependentProteinFluorescingInSpectrumRed .

JAX:022730 rdfs:subClassOf TEMPIND:Pvalb .

JAX:025112 rdfs:subClassOf TEMPIND:Penk .

JAX:028578 rdfs:subClassOf TEMPIND:VIP .

JAX:028579 rdfs:subClassOf TEMPIND:Sst .

JAX:029591 rdfs:subClassOf TEMPIND:GABA .

MMRRC:036680 rdfs:subClassOf TEMPIND:Htr3a .

NCBIGene:11535 rdfs:subClassOf TEMPIND:Adm .

NCBIGene:11998 rdfs:subClassOf TEMPIND:Avp .

NCBIGene:12307 rdfs:subClassOf TEMPIND:Calb .

NCBIGene:12308 rdfs:subClassOf TEMPIND:Calb2 .

NCBIGene:12310 rdfs:subClassOf TEMPIND:Calca .

NCBIGene:12424 rdfs:subClassOf TEMPIND:Cck .

NCBIGene:12426 rdfs:subClassOf TEMPIND:Cckbr .

NCBIGene:12647 rdfs:subClassOf TEMPIND:ACh .

NCBIGene:12801 rdfs:subClassOf TEMPIND:Cnr1 .

NCBIGene:12854 rdfs:subClassOf TEMPIND:Cort .

NCBIGene:12918 rdfs:subClassOf TEMPIND:Crh .

NCBIGene:13488 rdfs:subClassOf TEMPIND:Drd1 .

NCBIGene:13489 rdfs:subClassOf TEMPIND:Drd2 .

NCBIGene:13616 rdfs:subClassOf TEMPIND:Edn3 .

NCBIGene:14417 rdfs:subClassOf TEMPIND:GABA .

NCBIGene:15561 rdfs:subClassOf TEMPIND:Htr3a .

NCBIGene:15567 rdfs:subClassOf TEMPIND:Serotonin .

NCBIGene:16000 rdfs:subClassOf TEMPIND:Igf1 .

NCBIGene:18125 rdfs:subClassOf TEMPIND:Nos1 .

NCBIGene:18430 rdfs:subClassOf TEMPIND:Oxtr .

NCBIGene:18619 rdfs:subClassOf TEMPIND:Penk .

NCBIGene:19293 rdfs:subClassOf TEMPIND:Pvalb .

NCBIGene:20508 rdfs:subClassOf TEMPIND:ACh .

NCBIGene:20604 rdfs:subClassOf TEMPIND:Sst .

NCBIGene:21823 rdfs:subClassOf TEMPIND:TH .

NCBIGene:22348 rdfs:subClassOf TEMPIND:GABA .

NCBIGene:22353 rdfs:subClassOf TEMPIND:VIP .

NCBIGene:22354 rdfs:subClassOf TEMPIND:Vipr1 .

NCBIGene:22355 rdfs:subClassOf TEMPIND:Vipr2 .

NCBIGene:109648 rdfs:subClassOf TEMPIND:Npy .

NCBIGene:140919 rdfs:subClassOf TEMPIND:Glutamate .

NCBIGene:243764 rdfs:subClassOf TEMPIND:Chrm2 .

NIFEXT:5 rdfs:subClassOf TEMPIND:Calb2 .

NIFEXT:6 rdfs:subClassOf TEMPIND:Pvalb .

NIFEXT:5068 rdfs:subClassOf TEMPIND:Cck .

NIFEXT:5090 rdfs:subClassOf TEMPIND:Npy .

NIFEXT:5096 rdfs:subClassOf TEMPIND:Penk .

NIFEXT:5116 rdfs:subClassOf TEMPIND:Sst .

NIFEXT:5124 rdfs:subClassOf TEMPIND:Avp .

NIFEXT:5137 rdfs:subClassOf TEMPIND:Crh .

NIFEXT:5148 rdfs:subClassOf TEMPIND:VIP .

NIFEXT:5239 rdfs:subClassOf TEMPIND:GluR .

NIFEXT:5833 rdfs:subClassOf TEMPIND:Drd2 .

NIFEXT:5845 rdfs:subClassOf TEMPIND:Drd1 .

NLXMOL:1006006 rdfs:subClassOf TEMPIND:Calb .

NLXMOL:1006008 rdfs:subClassOf TEMPIND:ACh .

NLXMOL:1006009 rdfs:subClassOf TEMPIND:Glutamate .

NLXMOL:20090604 rdfs:subClassOf TEMPIND:GABAR .

PR:000001125 rdfs:subClassOf TEMPIND:Cnr1 .

PR:000001217 rdfs:subClassOf TEMPIND:Cckbr .

PR:000001614 rdfs:subClassOf TEMPIND:Chrm2 .

PR:000001635 rdfs:subClassOf TEMPIND:Oxtr .

PR:000003781 rdfs:subClassOf TEMPIND:Adm .

PR:000004967 rdfs:subClassOf TEMPIND:Calb .

PR:000004968 rdfs:subClassOf TEMPIND:Calb2 .

PR:000005110 rdfs:subClassOf TEMPIND:Cck .

PR:000005404 rdfs:subClassOf TEMPIND:ACh .

PR:000005767 rdfs:subClassOf TEMPIND:Cort .

PR:000005867 rdfs:subClassOf TEMPIND:Crh .

PR:000006899 rdfs:subClassOf TEMPIND:Edn3 .

PR:000007786 rdfs:subClassOf TEMPIND:GABA .

PR:000008833 rdfs:subClassOf TEMPIND:Htr3a .

PR:000009182 rdfs:subClassOf TEMPIND:Igf1 .

PR:000011326 rdfs:subClassOf TEMPIND:Nos1 .

PR:000011387 rdfs:subClassOf TEMPIND:Npy .

PR:000012544 rdfs:subClassOf TEMPIND:Penk .

PR:000013502 rdfs:subClassOf TEMPIND:Pvalb .

PR:000014962 rdfs:subClassOf TEMPIND:Glutamate .

PR:000014968 rdfs:subClassOf TEMPIND:ACh .

PR:000015084 rdfs:subClassOf TEMPIND:GABA .

PR:000015189 rdfs:subClassOf TEMPIND:Serotonin .

PR:000015665 rdfs:subClassOf TEMPIND:Sst .

PR:000016301 rdfs:subClassOf TEMPIND:TH .

PR:000017299 rdfs:subClassOf TEMPIND:VIP .

PR:000017300 rdfs:subClassOf TEMPIND:Vipr1 .

PR:000017301 rdfs:subClassOf TEMPIND:Vipr2 .

PR:000027222 rdfs:subClassOf TEMPIND:Calca .

PTHR:10558 rdfs:subClassOf TEMPIND:Sst .

PTHR:11653 rdfs:subClassOf TEMPIND:Pvalb .

SAO:185580330 rdfs:subClassOf TEMPIND:ACh .

SAO:229636300 rdfs:subClassOf TEMPIND:GABA .

SAO:289587392 rdfs:subClassOf TEMPIND:TH .

SAO:711465902 rdfs:subClassOf TEMPIND:Serotonin .

SAO:722953401 rdfs:subClassOf TEMPIND:ACh .

SAO:1744435799 rdfs:subClassOf TEMPIND:Glutamate .

### Serialized using the ttlser deterministic serializer v1.2.1