allen-transgenic-lines.ttl
type: Ontology
comment: Allen transgenic lines for cell types
version info: 2022-07-13
was generated by: allen cell types.py

Nr5a1-Cre
type: Class
IAO_0000115: Expressed in restricted populations within the hypothalamus (ventromedial hypothalamus), and in cortical layer 4.
subclass of: transgenicLine
has transgenic type: driverLine

Chat-IRES-Cre-neo
type: Class
IAO_0000115: Expressed in cholinergic neurons - restricted populations within the medulla, pons, thalamus, and midbrain; and in scattered cells within the striatum, basal forebrain, and a very sparse population of cells in the cortex.
subclass of: transgenicLine
has transgenic type: driverLine

Ai14(RCL-tdT)
type: Class
IAO_0000115: tdTomato fluorescent protein is expressed in cytoplasm
subclass of: transgenicLine
has transgenic type: reporterLine

Pvalb-IRES-Cre
type: Class
IAO_0000115: Expressed in restricted and/or sparse populations within the cerebellum, medulla, pons, midbrain, cortex, hippocampus, thalamus, and striatum.
subclass of: transgenicLine
has transgenic type: driverLine

Scnn1a-Tg2-Cre
type: Class
IAO_0000115: Reporter expression in sparse and/or restricted regions of cortex (layer 4), thalamus, midbrain, medulla, pons, and cerebellum.
subclass of: transgenicLine
has transgenic type: driverLine

Scnn1a-Tg3-Cre
type: Class
IAO_0000115: Enriched in cortical layer 4 and in restricted populations within cortex, thalamus, and in cerebellum.
subclass of: transgenicLine
has transgenic type: driverLine

Gad2-IRES-Cre
type: Class
IAO_0000115: Specific to GABAergic neurons. Enriched in the striatum, piriform cortex, and within restricted populations in the thalamus, hypothalamus, cerebellum, olfactory areas, and GABAergic interneurons of the cortex.
subclass of: transgenicLine
has transgenic type: driverLine

Vip-IRES-Cre
type: Class
IAO_0000115: Strong scattered expression throughout the brain. Enriched expression in superficial cortical layers and restricted populations in hindbrain and midbrain.
subclass of: transgenicLine
has transgenic type: driverLine

Sst-IRES-Cre
type: Class
IAO_0000115: Strong scattered expression throughout the brain. Localized areas of enrichment include restricted populations in thalamus, amygdala, midbrain, hindbrain, cortical subplate, and Purkinje cell layer.
subclass of: transgenicLine
has transgenic type: driverLine

Nos1-CreERT2
type: Class
IAO_0000115: Expressed in the molecular and granular layer in the cerebellum. Strong expression in the amygdala and olfactory bulb, particularly the accessory olfactory bulb, granular layer. Expressed in scattered cell populations in other brain regions.
subclass of: transgenicLine
has transgenic type: inducibleDriverLine

Nkx2-1-CreERT2
type: Class
IAO_0000115: Strong scattered cells in restricted populations throughout the brain including striatum, cortical subplate (amygdala), hippocampus, and hypothalamus. Expressed in choroid plexus.
subclass of: transgenicLine
has transgenic type: inducibleDriverLine

Pvalb-T2A-CreERT2
type: Class
IAO_0000115: Scattered expression throughout the cortex. Enriched in restricted populations in the cerebellum, medulla, pons, pallidum, and thalamus.
subclass of: transgenicLine
has transgenic type: inducibleDriverLine

Pvalb-T2A-Dre
type: Class
IAO_0000115: Dre expression is scattered throughout many regions of the brain including cortex, hippocampal formation, pons, and medulla; and in restricted populations within the pallidum, thalamus, midbrain, and cerebellum.
subclass of: transgenicLine
has transgenic type: driverLine

Ai65(RCFL-tdT)
type: Class
IAO_0000115: The expression of tdTomato fluorescent protein is dependent on both Cre and Flp recombinase activity.
subclass of: transgenicLine
has transgenic type: reporterLine

Ai66(RCRL-tdT)
type: Class
IAO_0000115: The expression of tdTomato fluorescent protein is dependent on both Cre and Dre recombinase activity.
subclass of: transgenicLine
has transgenic type: reporterLine

Pvalb-T2A-FlpO
type: Class
IAO_0000115: Scattered expression throughout the cortex. Enriched in restricted populations in the cerebellum, medulla, pons, pallidum, and thalamus.
subclass of: transgenicLine
has transgenic type: driverLine

Rorb-IRES2-Cre
type: Class
IAO_0000115: Strong expression in the zonal layer of the superior colliculus and subregions of thalamus. Dense, patchy expression in layer 4 and sparse expression in layer 5 and 6 in cortex. Also expressed in trigeminal nucleus and small patches of cells in cerebellum.
subclass of: transgenicLine
has transgenic type: driverLine

Penk-IRES2-Cre-neo
type: Class
IAO_0000115: Reporter expression is enriched in layers 2 and 6 of cortex and in restricted populations within olfactory areas, hippocampal formation, striatum, pallidum, and hypothalamus.
subclass of: transgenicLine
has transgenic type: driverLine

Ctgf-T2A-dgCre
type: Class
IAO_0000115: Cre expression is selective for layer 6b of cortex and in restricted populations within cortical subplate.
subclass of: transgenicLine
has transgenic type: driverLine

Ndnf-IRES2-dgCre
type: Class
IAO_0000115: Cre expression is restricted to layer 1 of cortex and in restricted populations within olfactory areas, hippocampal formation, striatum, and midbrain.
subclass of: transgenicLine
has transgenic type: driverLine

Sst-IRES-FlpO
type: Class
IAO_0000115: Scattered expression in cortical areas. Enrichment in populations of the amygdala, midbrain, and pons.
subclass of: transgenicLine
has transgenic type: driverLine

Slc17a6-IRES-Cre
type: Class
IAO_0000115: Widespread expression throughout most of the brain, except very sparse expression in the striatum and restricted populations within cerebellum, medulla, and pons.
subclass of: transgenicLine
has transgenic type: driverLine

Slc32a1-T2A-FlpO
type: Class
IAO_0000115: Widespread, scattered expression throughout the brain. Expressed in restricted populations within thalamus, hypothalamus, midbrain, pons, and medulla.
subclass of: transgenicLine
has transgenic type: driverLine

Esr2-IRES2-Cre
type: Class
IAO_0000115: Scattered expression in cortical layer 6. Restricted expression in the hypothalamus and amygdala.
subclass of: transgenicLine
has transgenic type: driverLine

Oxtr-T2A-Cre
type: Class
IAO_0000115: Cre expression is enriched in restricted populations within hippocampal formation, cortical subplate, striatum, thalamus, hypothalamus, and medulla. Sparse, scattered expression in cortex.
subclass of: transgenicLine
has transgenic type: driverLine

Vipr2-IRES2-Cre
type: Class
IAO_0000115: In subcortical areas, this Cre line has expression in arcuate hypothalamic nucleus, dorsal lateral geniculate nucleus, ventral nucleus of the thalamus, bed nuclei of the stria terminalis, and scattered expression in superior colliculus. In the cortex, there is scattered expression in neurons and non-neuronal cells.
subclass of: transgenicLine
has transgenic type: driverLine

Ntsr1-Cre_GN220
type: Class
IAO_0000115: Specific to cortical layer 6 neurons.
subclass of: transgenicLine
has transgenic type: driverLine

Rbp4-Cre_KL100
type: Class
IAO_0000115: Enriched in cortical layer 5 and the dentate gyrus.
subclass of: transgenicLine
has transgenic type: driverLine

Gng7-Cre_KH71
type: Class
IAO_0000115: Enriched in striatum and neocortical layers 2 and 5, and in restricted populations within the medulla, pons, midbrain, hippocampus, hypothalamus, thalamus, and olfactory areas.
subclass of: transgenicLine
has transgenic type: driverLine

Sim1-Cre_KJ18
type: Class
IAO_0000115: Enriched in restricted populations within layer 5 of cortex, striatum (amygdala), and hypothalamus. Sparse, scattered expression elsewhere in the brain.
subclass of: transgenicLine
has transgenic type: driverLine

Cux2-CreERT2
type: Class
IAO_0000115: Enriched in cortical layers 2/3/4, thalamus, midbrain, pons, medulla and cerebellum.
subclass of: transgenicLine
has transgenic type: inducibleDriverLine

Chrna2-Cre_OE25
type: Class
IAO_0000115: Enriched in cortical layer 5. Also expressed in restricted populations throughout the brain, including olfactory areas, hippocampus, lateral septal complex, pallidum, thalamus, hypothalamus, midbrain, hindbrain, and cerebellum.
subclass of: transgenicLine
has transgenic type: driverLine

Glt25d2-Cre_NF107
type: Class
IAO_0000115: Reporter expression displays laminar enrichment in rostral cortex and in restricted populations within cortical subplate.
subclass of: transgenicLine
has transgenic type: driverLine

Htr3a-Cre_NO152
type: Class
IAO_0000115: Reporter expression is detected in a subset of cortical interneurons. Enrichment is also detected in restricted populations within olfactory areas, pallidum, hypothalamus, pons, medulla, and cerebellum.
subclass of: transgenicLine
has transgenic type: driverLine

Tlx3-Cre_PL56
type: Class
IAO_0000115: Reporter expression is enriched in layer 5a of cortex and in restricted populations of pons and medulla.
subclass of: transgenicLine
has transgenic type: driverLine