@prefix : <file:///ERROR/EMPTY/PREFIX/BANNED/> .
@prefix definition: <http://purl.obolibrary.org/obo/IAO_0000115> .
@prefix ilxtr: <http://uri.interlex.org/tgbugs/uris/readable/> .
@prefix JAX: <http://jaxmice.jax.org/strain/> .
@prefix MMRRC: <http://www.mmrrc.org/catalog/getSDS.jsp?mmrrc_id=> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .

<https://raw.githubusercontent.com/SciCrunch/NIF-Ontology/neurons/ttl/generated/allen-transgenic-lines.ttl> a owl:Ontology ;
    rdfs:comment "Allen transgenic lines for cell types" ;
    owl:versionInfo "2022-07-13" ;
    prov:wasGeneratedBy <https://github.com/tgbugs/pyontutils/blob/uncommitted@cf3e60cc/neurondm/neurondm/models/allen_cell_types.py> .

### Classes

JAX:006364 a owl:Class ;
    rdfs:label "Nr5a1-Cre" ;
    definition: "Expressed in restricted populations within the hypothalamus (ventromedial hypothalamus), and in cortical layer 4. " ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:006410 a owl:Class ;
    rdfs:label "Chat-IRES-Cre-neo" ;
    definition: "Expressed in cholinergic neurons - restricted populations within the medulla, pons, thalamus, and midbrain; and in scattered cells within the striatum, basal forebrain, and a very sparse population of cells in the cortex." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:007914 a owl:Class ;
    rdfs:label "Ai14(RCL-tdT)" ;
    definition: "tdTomato fluorescent protein is expressed in cytoplasm" ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:reporterLine .

JAX:008069 a owl:Class ;
    rdfs:label "Pvalb-IRES-Cre" ;
    definition: "Expressed in restricted and/or sparse populations within the cerebellum, medulla, pons, midbrain, cortex, hippocampus, thalamus, and striatum." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:009112 a owl:Class ;
    rdfs:label "Scnn1a-Tg2-Cre" ;
    definition: "Reporter expression in sparse and/or restricted regions of cortex (layer 4), thalamus, midbrain, medulla, pons, and cerebellum." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:009613 a owl:Class ;
    rdfs:label "Scnn1a-Tg3-Cre" ;
    definition: "Enriched in cortical layer 4 and in restricted populations within cortex, thalamus, and in cerebellum." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:010802 a owl:Class ;
    rdfs:label "Gad2-IRES-Cre" ;
    definition: "Specific to GABAergic neurons. Enriched in the striatum, piriform cortex, and within restricted populations in the thalamus, hypothalamus, cerebellum, olfactory areas, and GABAergic interneurons of the cortex." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:010908 a owl:Class ;
    rdfs:label "Vip-IRES-Cre" ;
    definition: "Strong scattered expression throughout the brain. Enriched expression in superficial cortical layers and restricted populations in hindbrain and midbrain. " ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:013044 a owl:Class ;
    rdfs:label "Sst-IRES-Cre" ;
    definition: "Strong scattered expression throughout the brain. Localized areas of enrichment include restricted populations in thalamus, amygdala, midbrain, hindbrain, cortical subplate, and Purkinje cell layer. " ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:014541 a owl:Class ;
    rdfs:label "Nos1-CreERT2" ;
    definition: "Expressed in the molecular and granular layer in the cerebellum. Strong expression in the amygdala and olfactory bulb, particularly the accessory olfactory bulb, granular layer. Expressed in scattered cell populations in other brain regions." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:inducibleDriverLine .

JAX:014552 a owl:Class ;
    rdfs:label "Nkx2-1-CreERT2" ;
    definition: "Strong scattered cells in restricted populations throughout the brain including striatum, cortical subplate (amygdala), hippocampus, and hypothalamus. Expressed in choroid plexus." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:inducibleDriverLine .

JAX:021189 a owl:Class ;
    rdfs:label "Pvalb-T2A-CreERT2" ;
    definition: "Scattered expression throughout the cortex. Enriched in restricted populations in the cerebellum, medulla, pons, pallidum, and thalamus." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:inducibleDriverLine .

JAX:021190 a owl:Class ;
    rdfs:label "Pvalb-T2A-Dre" ;
    definition: "Dre expression is scattered throughout many regions of the brain including cortex, hippocampal formation, pons, and medulla; and in restricted populations within the pallidum, thalamus, midbrain, and cerebellum." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:021875 a owl:Class ;
    rdfs:label "Ai65(RCFL-tdT)" ;
    definition: "The expression of tdTomato fluorescent protein is dependent on both Cre and Flp recombinase activity." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:reporterLine .

JAX:021876 a owl:Class ;
    rdfs:label "Ai66(RCRL-tdT)" ;
    definition: "The expression of tdTomato fluorescent protein is dependent on both Cre and Dre recombinase activity." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:reporterLine .

JAX:022730 a owl:Class ;
    rdfs:label "Pvalb-T2A-FlpO" ;
    definition: "Scattered expression throughout the cortex. Enriched in restricted populations in the cerebellum, medulla, pons, pallidum, and thalamus." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:023526 a owl:Class ;
    rdfs:label "Rorb-IRES2-Cre" ;
    definition: "Strong expression in the zonal layer of the superior colliculus and subregions of thalamus.  Dense, patchy expression in layer 4 and sparse expression in layer 5 and 6 in cortex. Also expressed in trigeminal nucleus and small patches of cells in cerebellum." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:025112 a owl:Class ;
    rdfs:label "Penk-IRES2-Cre-neo" ;
    definition: "Reporter expression is enriched in layers 2 and 6 of cortex and in restricted populations within olfactory areas, hippocampal formation, striatum, pallidum, and hypothalamus." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:028535 a owl:Class ;
    rdfs:label "Ctgf-T2A-dgCre" ;
    definition: "Cre expression is selective for layer 6b of cortex and in restricted populations within cortical subplate." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:028536 a owl:Class ;
    rdfs:label "Ndnf-IRES2-dgCre" ;
    definition: "Cre expression is restricted to layer 1 of cortex and in restricted populations within olfactory areas, hippocampal formation, striatum, and midbrain." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:028579 a owl:Class ;
    rdfs:label "Sst-IRES-FlpO" ;
    definition: "Scattered expression in cortical areas. Enrichment in populations of the amygdala, midbrain, and pons." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:028863 a owl:Class ;
    rdfs:label "Slc17a6-IRES-Cre" ;
    definition: "Widespread expression throughout most of the brain, except very sparse expression in the striatum and restricted populations within cerebellum, medulla, and pons." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:029591 a owl:Class ;
    rdfs:label "Slc32a1-T2A-FlpO" ;
    definition: "Widespread, scattered expression throughout the brain. Expressed in restricted populations within thalamus, hypothalamus, midbrain, pons, and medulla." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:030158 a owl:Class ;
    rdfs:label "Esr2-IRES2-Cre" ;
    definition: "Scattered expression in cortical layer 6. Restricted expression in the hypothalamus and amygdala." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:031303 a owl:Class ;
    rdfs:label "Oxtr-T2A-Cre" ;
    definition: "Cre expression is enriched in restricted populations within hippocampal formation, cortical subplate, striatum, thalamus, hypothalamus, and medulla. Sparse, scattered expression in cortex." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

JAX:031332 a owl:Class ;
    rdfs:label "Vipr2-IRES2-Cre" ;
    definition: "In subcortical areas, this Cre line has expression in arcuate hypothalamic nucleus, dorsal lateral geniculate nucleus, ventral nucleus of the thalamus, bed nuclei of the stria terminalis, and scattered expression in superior colliculus. In the cortex, there is scattered expression in neurons and non-neuronal cells." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:030648 a owl:Class ;
    rdfs:label "Ntsr1-Cre_GN220" ;
    definition: "Specific to cortical layer 6 neurons." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:031125 a owl:Class ;
    rdfs:label "Rbp4-Cre_KL100" ;
    definition: "Enriched in cortical layer 5 and the dentate gyrus." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:031181 a owl:Class ;
    rdfs:label "Gng7-Cre_KH71" ;
    definition: "Enriched in striatum and neocortical layers 2 and 5, and in restricted populations within the medulla, pons, midbrain, hippocampus, hypothalamus, thalamus, and olfactory areas." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:031742 a owl:Class ;
    rdfs:label "Sim1-Cre_KJ18" ;
    definition: "Enriched in restricted populations within layer 5 of cortex, striatum (amygdala), and hypothalamus. Sparse, scattered expression elsewhere in the brain." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:032779 a owl:Class ;
    rdfs:label "Cux2-CreERT2" ;
    definition: "Enriched in cortical layers 2/3/4, thalamus, midbrain, pons, medulla and cerebellum. " ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:inducibleDriverLine .

MMRRC:036502 a owl:Class ;
    rdfs:label "Chrna2-Cre_OE25" ;
    definition: "Enriched in cortical layer 5. Also expressed in restricted populations throughout the brain, including olfactory areas, hippocampus, lateral septal complex, pallidum, thalamus, hypothalamus, midbrain, hindbrain, and cerebellum." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:036504 a owl:Class ;
    rdfs:label "Glt25d2-Cre_NF107" ;
    definition: "Reporter expression displays laminar enrichment in rostral cortex and in restricted populations within cortical subplate." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:036680 a owl:Class ;
    rdfs:label "Htr3a-Cre_NO152" ;
    definition: "Reporter expression is detected in a subset of cortical interneurons. Enrichment is also detected in restricted populations within olfactory areas, pallidum, hypothalamus, pons, medulla, and cerebellum." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

MMRRC:041158 a owl:Class ;
    rdfs:label "Tlx3-Cre_PL56" ;
    definition: "Reporter expression is enriched in layer 5a of cortex and in restricted populations of pons and medulla." ;
    rdfs:subClassOf ilxtr:transgenicLine ;
    ilxtr:hasTransgenicType ilxtr:driverLine .

### Serialized using the ttlser deterministic serializer v1.2.0