dorsal root ganglion type A nerve fiber +PV (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +PV +PV (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +PVALB (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +PVALB (implies Macaca mulatta sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +Pvalb (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber (unionOf slowly adapting type 1 (SA1) nerve fiber field-type cutaneous mechanosensitivity) +(intersection-of Ntrk3) (unionOf +Grm8 +S100a16) low-threshold mechanosensitivity (LTM) (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
DRG TG Ntrk3^high+S100a16 mouse (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber (unionOf slowly adapting type 1 (SA1) nerve fiber field-type cutaneous mechanosensitivity) +(intersection-of TrkC) (unionOf +Grm8 +S100a16) +JAX:030291 low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
DRG TG Ntrk3^high+S100a16 human (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber (unionOf slowly adapting type 1 (SA1) nerve fiber field-type cutaneous mechanosensitivity) +(intersection-of TRKC) +GRM8 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
DRG TG Ntrk3^high+S100a16 macaque (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber (unionOf slowly adapting type 1 (SA1) nerve fiber field-type cutaneous mechanosensitivity) +(intersection-of ilxtr:HigherExpression NTRK3) (unionOf +GRM8 +S100A16) low-threshold mechanosensitivity (LTM) (implies Macaca mulatta sensory) neuron (Precision)
DRG TG Ntrk3^high+S100a16 guinea pig (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber (unionOf slowly adapting type 1 (SA1) nerve fiber field-type cutaneous mechanosensitivity) +(intersection-of ilxtr:HigherExpression Ntrk3) +S100a16 low-threshold mechanosensitivity (LTM) (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber rapidly adapting (RA) nerve fiber +(intersection-of Ntrk3) +Ntrk2 low-threshold mechanosensitivity (LTM) (implies Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
DRG TG Ntrk3^high+Ntrk2 mouse (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber rapidly adapting (RA) nerve fiber +(intersection-of TrkC) (unionOf +Calb +Ntrk2) +Npy2r-GFP-Ret-CreER low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
DRG TG Ntrk3^high+Ntrk2 human (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber rapidly adapting (RA) nerve fiber +(intersection-of TRKC) +OBHD low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
DRG TG Ntrk3^high+Ntrk2 macaque (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aβ (beta) nerve fiber rapidly adapting (RA) nerve fiber +(intersection-of ilxtr:HigherExpression NTRK3) +NTRK2 low-threshold mechanosensitivity (LTM) (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +(intersection-of Ntrk3) +Ntrk2 low-threshold mechanosensitivity (LTM) (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
DRG TG Ntrk3^low+Ntrk2 mouse (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +(intersection-of TrkC) +Ntrk2 +Ntrk2-CreER low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
DRG TG Ntrk3^low+Ntrk2 human (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +(intersection-of TRKC) +OBHD low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
DRG TG Ntrk3^low+Ntrk2 macaque (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +(intersection-of ilxtr:LowerExpression NTRK3) +NTRK2 low-threshold mechanosensitivity (LTM) (implies Macaca mulatta sensory) neuron (Precision)
DRG TG Ntrk3^low+Ntrk2 guinea pig (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +(intersection-of ilxtr:LowerExpression Ntrk3) +TrkB low-threshold mechanosensitivity (LTM) (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +Calca +Smr2 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber (unionOf +Chrna7 +Smr2) +Calca +JAX:039562 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +CHRNA7 +CT heat-sensitive high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +CGRP +CHRNA7 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Macaca mulatta sensory) neuron (Precision)
DRG TG Calca+Smr2 guinea pig (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +LOC100720640 +Tac1 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +Bmpr1b +Calca high-threshold mechanosensitivity (HTM) (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +Bmpr1b +Calca +JAX:039561 high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +CT +KIT high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
DRG TG DRG Calca+Bmpr1b macaque (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +CGRP +KIT high-threshold mechanosensitivity (HTM) (implies Macaca mulatta sensory) neuron (Precision)
DRG TG Calca+Bmpr1b guinea pig (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type Aδ (delta) nerve fiber +Kit +Tac1 high-threshold mechanosensitivity (HTM) (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Th low-threshold mechanosensitivity (LTM) (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Cdh9 +TH +JAX:025614 low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +CDH9 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +CDH9 low-threshold mechanosensitivity (LTM) (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Cdh9 low-threshold mechanosensitivity (LTM) (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Mrgprd heat-sensitive high-threshold mechanosensitivity (HTM) (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber (unionOf +Gfra1 +Mrgprd +NaN) +JAX:031286 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +GFRA1 +NaN heat-sensitive high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber (unionOf +GFRA1 +MGRD +SCN11A) heat-sensitive high-threshold mechanosensitivity (HTM) (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Gfra1 +Scn11a heat-sensitive high-threshold mechanosensitivity (HTM) (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Mrgpra3 +Trpv1 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
DRG TG Mrgpra3+Trpv1 mouse (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Mrgpra3 +Trpv1 +Mrgpra3-Cre heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Mrgpra3 +Mrgprb4 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
DRG TG Mrgpra3+Mrgprb4 mouse (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Mrgpra3 +Mrgprb4 +JAX:021077 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Calca +Sstr2 heat-sensitive (implies Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber (unionOf +Ptprt +Sstr2) +Calca +JAX:039563 heat-sensitive (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +CT +PTPRT heat-sensitive (implies Homo sapiens sensory) neuron (Precision)
DRG TG Calca+Sstr2 macaque (Bhuiyan2024)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +CGRP +PTPRT heat-sensitive (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +Calca +Oprk1 (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +Calca +Oprk1 +JAX:035045 (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +Adra2a +Calca (implies Homo sapiens Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +Adra2a +Calca +JAX:039560 (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +ADRA2A +CT (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion +Calca +Dcn (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion +Rxfp1 (implies Macaca mulatta Mus musculus sensory) neuron (Precision)
dorsal root ganglion +Rxfp1 (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion +LGR7 (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Trpm8 cold-sensitive (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
dorsal root ganglion trigeminal ganglion type C nerve fiber +Trpm8 +Trpm8-Cre-Trpm8-Flpo cold-sensitive (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +TRPM8 cold-sensitive (implies Homo sapiens sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +TRPM8 cold-sensitive (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Trpm8 cold-sensitive (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Sst heat-sensitive high-threshold mechanosensitivity (HTM) (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Sst +Cysltr2-Cre-Sst-Cre heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +SST heat-sensitive high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +SST heat-sensitive high-threshold mechanosensitivity (HTM) (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) type C nerve fiber +Sst heat-sensitive high-threshold mechanosensitivity (HTM) (implies Cavia porcellus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +Atf3 (implies Cavia porcellus Homo sapiens Macaca mulatta Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +Atf3 +JAX:037483 (implies Mus musculus sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +ATF3 (implies Homo sapiens sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +ATF3 (implies Macaca mulatta sensory) neuron (Precision)
(unionOf dorsal root ganglion trigeminal ganglion) +Atf3 (implies Cavia porcellus sensory) neuron (Precision)
see Table S12 of https://doi.org/10.1101/2025.11.05.686654 for asserted equivalences
dorsal root ganglion type Aβ (beta) nerve fiber +NCBIGene:2115 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber +NCBIGene:55203 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber +NCBIGene:51617 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber +NCBIGene:886 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +NCBIGene:6866 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +NCBIGene:404037 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +NCBIGene:2042 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +NCBIGene:5100 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +peptide +CHRNA7 +NCBIGene:6572 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +peptide +NCBIGene:140576 +TRKC (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +peptide +KIT (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +peptide +NCBIGene:10590 +NCBIGene:152 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion +ATF3 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +peptide +NCBIGene:1136 +NCBIGene:6863 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +peptide +NCBIGene:27091 +NCBIGene:6863 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +peptide +NCBIGene:136 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +NCBIGene:259249 +NCBIGene:2675 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +NCBIGene:117196 +NCBIGene:259249 (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +SST (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +CDH9 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
see Figure 1G of https://doi.org/10.1038/s42003-025-08315-1 for asserted equivalences to Yu et al., 2024. See Table S12 for asserted equivalences to Bhuyian et al., 2025.
dorsal root ganglion type C nerve fiber +NCBIGene:59350 heat-sensitive (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +TRPM8 heat-sensitive (implies Homo sapiens sensory) neuron (Precision)
DRG proprioceptor (Tavares-Ferreira2022)
dorsal root ganglion type A nerve fiber +NCBIGene:3787 +NCBIGene:41 +PVALB (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber slowly adapting type 1 (SA1) nerve fiber +PVALB +TRKC low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber rapidly adapting (RA) nerve fiber +(intersection-of OBHD) +(intersection-of TRKC) low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aδ (delta) nerve fiber +(intersection-of OBHD) low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
DRG pututive Ab nociceptor (Tavares-Ferreira2022)
dorsal root ganglion type Aβ (beta) nerve fiber slowly adapting type 1 (SA1) nerve fiber +NCBIGene:6336 +TRKC low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
DRG cold nociceptor (Tavares-Ferreira2022)
dorsal root ganglion +NCBIGene:6336 +TRPM8 cold-sensitive (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aδ (delta) nerve fiber +NCBIGene:6336 +NCBIGene:9362 high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
DRG PENK nociceptor (Tavares-Ferreira2022)
dorsal root ganglion +NCBIGene:5179 (implies Homo sapiens sensory) neuron (Precision)
DRG TRPA1 nociceptor (Tavares-Ferreira2022)
dorsal root ganglion +NCBIGene:8989 (implies Homo sapiens sensory) neuron (Precision)
DRG putative silent nociceptor (Tavares-Ferreira2022)
dorsal root ganglion +NCBIGene:1136 (implies Homo sapiens sensory) neuron (Precision)
DRG pruritogen receptor enriched (Tavares-Ferreira2022)
dorsal root ganglion (unionOf +NCBIGene:4879) (implies Homo sapiens sensory) neuron (Precision)
DRG putative C-LTMR (Tavares-Ferreira2022)
dorsal root ganglion type C nerve fiber +NCBIGene:2675 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
expressed PNS neuronal markers: SLC17A6, SYP and UCHL1
dorsal root ganglion type C nerve fiber +(intersection-of ilxtr:HigherExpression TRPM8) +NCBIGene:375057 TEMP:MISSING_ (implies Homo sapiens sensory) neuron (Precision)
for asserted relations see Fig 2c of Yu et al., 2024 https://doi.org/10.1038/s41593-024-01794-1
dorsal root ganglion type C nerve fiber +NCBIGene:845 low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +(intersection-of ilxtr:HigherExpression NCBIGene:3269) +NCBIGene:259249 +NCBIGene:4985 high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
HTMR phenotype suggested based on microneurography recordings
dorsal root ganglion type C nerve fiber +(intersection-of ilxtr:HigherExpression NCBIGene:3269) +(intersection-of ilxtr:HigherExpression NCBIGene:7442) +NCBIGene:117196 +NCBIGene:259249 +NCBIGene:4985 high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
SST+ nerve fibers also identified by immunostaining in epidermis-dermis junction, and near hair follicles. c fiber and HTMR phenotype suggested based on microneurography recordings
asserted equivalent to macaque NP3 & mouse NP3: https://doi.org/10.1038/nn.3881
Macaque study: https://pubmed.ncbi.nlm.nih.gov/33686078/ ; monkey study: https://pubmed.ncbi.nlm.nih.gov/31915380/
dorsal root ganglion (with-axon-sensory-subcellular-element-in dermis skin) type C nerve fiber +(intersection-of ilxtr:HigherExpression NCBIGene:7442) +CT +NCBIGene:133396 +NCBIGene:2676 +NCBIGene:3269 +NCBIGene:885 +SST high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
c fiber and HTMR phenotype suggested based on microneurography recordings
dorsal root ganglion type C nerve fiber +peptide +(intersection-of ilxtr:HigherExpression NCBIGene:7442) +NCBIGene:63895 +NCBIGene:8989 high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
suggested thermoreceptive, also possible innervation target = deep tissues
dorsal root ganglion type C nerve fiber +peptide +NCBIGene:7442 +NCBIGene:8989 TEMP:MISSING_ (implies Homo sapiens sensory) neuron (Precision)
suggested innervation target = blood vessels and internal organ mechanical forces (e.g., bladder). For asserted relationships, see fig 1g of Krauter et al., 2025
dorsal root ganglion type A nerve fiber +peptide +(intersection-of ilxtr:HigherExpression NCBIGene:63895) +NCBIGene:152 +NCBIGene:183 +NCBIGene:4988 +NCBIGene:5739 +NCBIGene:8111 TEMP:MISSING_ (implies Homo sapiens sensory) neuron (Precision)
HTMR phenotype asserted based on microneurography
for asserted relations see Fig 2c of Yu et al., 2024 https://doi.org/10.1038/s41593-024-01794-1 and Krauter et al., 2025 Figure 1g
dorsal root ganglion type A nerve fiber +peptide +(intersection-of ilxtr:LowerExpression TRPM8) +NCBIGene:4988 high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
check out retrograde tracing study to mouse gastrocnemius muscle https://pubmed.ncbi.nlm.nih.gov/24316076/
dorsal root ganglion type A nerve fiber +peptide +CHRNA7 +NCBIGene:4988 +PVALB TEMP:MISSING_ (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +peptide +(intersection-of TRKC) +(intersection-of ilxtr:HigherExpression NCBIGene:6275) +(intersection-of ilxtr:LowerExpression NCBIGene:63895) +NCBIGene:4988 high-threshold mechanosensitivity (HTM) (implies Homo sapiens sensory) neuron (Precision)
expressed PNS neuronal markers: SLC17A6, SYP and UCHL1. Asserted subtype relations per Krauter et al., 2025 Figure 1g.
dorsal root ganglion type A nerve fiber +peptide +(intersection-of ilxtr:ModerateExpression NCBIGene:63895) +CT TEMP:MISSING_ (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aδ (delta) nerve fiber low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +NCBIGene:7905 +PVALB low-threshold mechanosensitivity (LTM) (implies Homo sapiens sensory) neuron (Precision)
ATF is a transcription factor associated with sensory afferent injury.
dorsal root ganglion (with-axon-sensory-subcellular-element-in TEMP:MISSING_) type A nerve fiber (implies Homo sapiens sensory) neuron (Precision)
see Figure 1G of https://doi.org/10.1038/s42003-025-08315-1 for asserted equivalences to Yu et al., 2024
dorsal root ganglion type C nerve fiber +Rxfp1 (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +Foxp2 +Pnoc (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +Foxp2 +NCBIGene:332309 cold-sensitive heat-sensitive (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +Sstr2 (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion TEMP:MISSING_ type C nerve fiber +NCBIGene:54140 +Sstr2 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion TEMP:MISSING_ type C nerve fiber +Dcn heat-sensitive (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +Adra2a heat-sensitive (implies Mus musculus sensory) neuron (Precision)
see Figure 1G of https://doi.org/10.1038/s42003-025-08315-1 for asserted equivalences to Yu et al., 2024. Subclass to Bhuiyan 2025 asserted in Bhuyian 2025
dorsal root ganglion type C nerve fiber +NCBIGene:381310 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
see Figure 1G of https://doi.org/10.1038/s42003-025-08315-1 for asserted equivalences to Yu et al., 2024. see Table S12 for asserted equivalences to Bhuyian et al., 2025
dorsal root ganglion type C nerve fiber +Oprk1 heat-sensitive (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +Smr2 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +E1 high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +Bmpr1b +NCBIGene:53972 high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type A nerve fiber +Bmpr1b +NCBIGene:246313 high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +Sstr2 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
see Figure 1G of https://doi.org/10.1038/s42003-025-08315-1 for asserted equivalences to Yu et al., 2024. see Table S12 of https://doi.org/10.1101/2025.11.05.686654 for asserted equivalences to Bhuyian et al., 2025
dorsal root ganglion type C nerve fiber +Mrgpra3 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +Mrgpra3 +Mrgprb4 TEMP:MISSING_ heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +NCBIGene:239556 low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type Aδ (delta) nerve fiber +E1 high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber rapidly adapting (RA) nerve fiber +Calb low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type Aβ (beta) nerve fiber +Syt1 field-type cutaneous mechanosensitivity low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion +Cux2 (implies Mus musculus sensory) neuron (Precision)
E12 tamoxifen for SA1, postnatal tamoxifen for field
dorsal root ganglion (with-axon-sensory-subcellular-element-in skin of body) type Aβ (beta) nerve fiber slowly adapting type 1 (SA1) nerve fiber field-type cutaneous mechanosensitivity low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina III Rexed lamina IV) (with-axon-sensory-subcellular-element-in hair follicle) TEMP:MISSING_ type Aβ (beta) nerve fiber rapidly adapting (RA) nerve fiber +NCBIGene:667742 field-type cutaneous mechanosensitivity (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II Rexed lamina III) (with-axon-sensory-subcellular-element-in hair follicle) type Aδ (delta) nerve fiber +NCBIGene:667742 low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II) (with-axon-sensory-subcellular-element-in hair follicle) type C nerve fiber +NCBIGene:667742 +JAX:025614 low-threshold mechanosensitivity (LTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II lamina I of gray matter of spinal cord) (with-axon-sensory-subcellular-element-in skin of body) type C nerve fiber +peptide +(intersection-of Vr1) +Calca +Sstr2 heat-sensitive (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +peptide +Oprk1 (implies Mus musculus sensory) neuron (Precision)
some terminals go deeper than rexed laminae II
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II lamina I of gray matter of spinal cord) (with-axon-sensory-subcellular-element-in skin of body) type Aδ (delta) nerve fiber slowly adapting type 1 (SA1) nerve fiber +peptide +Bmpr1b +Calca +NCBIGene:667742 high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-sensory-subcellular-element-in colon urinary bladder) +peptide +Adra2a +Calca (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II) (with-axon-sensory-subcellular-element-in skin of body) type C nerve fiber slowly adapting type 1 (SA1) nerve fiber +peptide +(intersection-of Vr1) +Mrgpra3 +NCBIGene:667742 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II) (with-axon-sensory-subcellular-element-in skin of body) type C nerve fiber slowly adapting type 1 (SA1) nerve fiber +peptide +Mrgprb4 +NCBIGene:667742 +JAX:021077 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II lamina I of gray matter of spinal cord) (with-axon-sensory-subcellular-element-in skin of body) type Aδ (delta) nerve fiber slowly adapting type 1 (SA1) nerve fiber +peptide +Calca +NCBIGene:667742 +Smr2 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion type C nerve fiber +peptide (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II) (with-axon-sensory-subcellular-element-in skin of body) TEMP:MISSING_ type C nerve fiber slowly adapting type 1 (SA1) nerve fiber +Mrgprd +NCBIGene:667742 +JAX:031286 heat-sensitive (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion field-type cutaneous mechanosensitivity (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in Rexed lamina II lamina I of gray matter of spinal cord) (with-axon-sensory-subcellular-element-in skin of body) type C nerve fiber +(intersection-of Vr1) +NCBIGene:16188 +NCBIGene:18158 +NCBIGene:28240 +NCBIGene:667742 +Sstr2 heat-sensitive high-threshold mechanosensitivity (HTM) (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (with-axon-presynaptic-element-in lamina I of gray matter of spinal cord) (with-axon-sensory-subcellular-element-in skin of body) type C nerve fiber +TEMP:MISSING_ field-type cutaneous mechanosensitivity (implies Mus musculus sensory) neuron (Precision)
dorsal root ganglion (implies Mus musculus sensory) neuron (Precision)
(with-axon-sensory-subcellular-element-in TEMP:MISSING_) neuron (Precision)
(with-axon-sensory-subcellular-element-in TEMP:MISSING_) +TEMP:MISSING_ neuron (Precision)