Clair A. Kronk GSSO is the Gender, Sex, and Sex Orientation ontology, including terms related to gender identity and expression, sexual and romantic identity and orientation, and sexual and reproductive behavior. GSSO - the Gender, Sex, and Sexual Orientation ontology masculine gender third person definition contributor date description format identifier_dc identifier language publisher relation rights subject_dc subject title_dc title type_dc type abstract access rights accrual method alternative title date available conforms to contributor date created creator date date accepted date copyrighted date submitted description format has format has part has version identifier_dc_terms identifier is format of is part of is referenced by is replaced by is required by is version of date issued language license date modified publisher references relation replaces requires rights source subject_dc_terms subject title_dc_terms title type_dc_terms type article common noun definite article determiner feminine gender first person gender property indefinite article linguistic property linguistic properties morphosyntactic property neuter gender noun part of speech property part of speech properties person property personal pronoun possessive pronoun pro-form pronominal proper noun reflexive pronoun relative pronoun second person consider has alternative identifier has broad synonym has date has database cross reference has default namespace has definition has exact synonym has narrow synonym has OBO namespace has related synonym has subset has synonym has synonym type has URI has version in subset is cyclic replaced by saved by comment is defined by A human-readable name for the subject. label see_also_rdf_schema see also different from equivalent property inverse of additional name address affiliation alternate name alumni of award birthdate birthplace book edition children clip number colleague date created date modified date posted date published date of death deathplace dissolution date editor end date episode number family name founding date gender given name Global Location Number has occupation height honorific prefix honorific suffix identifier_schema identifier image in language inverse of ISBN ISSN issue number knows language legislation date license location logo member of name nationality number of pages page end page start pagination photo position same as season number sibling spouse start date street address subject of url_schema URL volume number weight library_of_congress_subject_headings Library of Congress Subject Headings http://purl.org/dc/terms/LCSH https://viaf.org/viaf/174475040 dewey_decimal_classification Dewey Decimal Classification nlm_unique_id NLM Unique ID illustrator illustrator founded_by founded by library_of_congress_classification Library of Congress Classification universal_decimal_classification Universal Decimal Classification terminologia_anatomica_98_id Terminologia Anatomica 98 ID named_after named after partially_coincident_with partially coincident with glottolog_code Glottolog code foundational_model_of_anatomy_id Foundational Model of Anatomy ID nickname nickname birth_name birth name used_by used by has_effect has effect demonym demonym follows follows uberon_id UBERON ID followed_by followed by youtube_video_id YouTube Video ID see_also_wikidata see also quote quote quotes icd10pcs ICD-10-PCS icd9cm ICD-9-CM terminologia_embryologica Terminologia Embryologica terminologia_histologica Terminologia Histologica inverse_of inverse of creator creator nci_thesaurus_id NCI Thesaurus ID performer performer named_as named as short_name short name hathitrust_id HathiTrust ID different_from different from dsm5_classification DSM-5 Classification wikisource_index_page Wikisource Index Page project_gutenberg_ebook_id Project Gutenberg eBook ID isbn13 ISBN-13 isni ISNI viaf_id VIAF ID medical_condition_treated medical condition treated iso_639_1_code ISO 639-1 code iso_639_2_code ISO 639-2 code iso_639_3_code ISO 639-3 code uses uses name name married_name married name culture culture https://www.wikidata.org/wiki/Property:P267 atc_code ATC Code url_wikidata URL country_of_citizenship country of citizenship location location month in year month in year for periodic occurrence practiced_by practiced by medical_dictionary_for_regulatory_activities_id Medical Dictionary for Regulatory Activities ID encoding encoding code code RxNorm ID imdb_id IMDb ID entrez_gene_id Entrez Gene ID uniprot_protein_id UniProt Protein ID hgnc_gene_symbol HGNC Gene Symbol hgnc_id HGNC ID doi DOI relations_ontology_id Relations Ontology ID part_of part of use use human_phenotype_ontology_id Human Phenotype Ontology ID named_by named by global_trade_item_number Global Trade Item Number icd10cm ICD-10-CM opposite_of opposite of color color mesh_descriptor_id Such as C004931 for DPPH or D008180 for systemic lupus erythematosus. MeSH Descriptor ID omim_id OMIM ID author author patronym_or_matronym_for_this_person patronym or matronym for this person cause_of_death cause of death derived_from derived from oclc_work_id OCLC work ID inception inception time_of_discovery_or_invention time of discovery or invention start_time start time snomed_ct_identifier SNOMED CT Identifier point_in_time point in time ec_enzyme_number EC enzyme number ensembl_gene_id Ensembl Gene ID A word or phrase in another language that corresponds exactly to this meaning of the lexeme. translation translation translations discoverer inventor discoverer_or_inventor discoverer or inventor route_of_administration route of administration refseq_protein_id RefSeq Protein ID refseq_rna_id RefSeq RNA ID preferred_pronoun preferred pronoun proquest_document_id ProQuest Document ID dsm4_classification DSM-IV Classification mesh_term_id Such as T001967 for amoxapine or T027926 for neoplasm. MeSH Term ID mesh_concept_id Such as M0001008 for amoxapine or M0014585 for neoplasm. MeSH Concept ID mesh_code Such as "A07" for circulatory system or "A07.231.114.056" for aorta. MeSH Code MeSH Tree Number google_books_id Google Books ID chebi_id ChEBI ID https://creativecommons.org/licenses/by/4.0/ ncbi_taxonomy_id NCBI Taxonomy ID gene_ontology_id Gene Ontology ID encodes encodes pubmed_id PubMed ID disease_ontology_id Disease Ontology ID encoded_by encoded by found_in_taxon found in taxon ensembl_transcript_id Ensembl Transcript ID ensembl_protein_id Ensembl Protein ID internet_archive_id Internet Archive ID pseudonym pseudonym date_of_disappearance date of disappearance symptom symptom symptoms has_cause has cause day_in_year_for_periodic_occurrence day in year for periodic occurrence official_website official website https://www.wikidata.org/wiki/Property:P8824 attraction_to attraction to jstor_article_id JSTOR Article ID anatomical_location anatomical location pmcid PMCID isbn10 ISBN-10 A rare condition characterized by the complete absence of the penis. http://homosaurus.org/v2/aphallia absent penis aphallia aphallus aplasia of the penis congenital absence and aplasia of penis congenital absence of penis agenesis of the penis penis agenesis penile agenesis http://purl.obolibrary.org/obo/NCIT_C99009 http://purl.obolibrary.org/obo/HP_0030261 http://purl.bioontology.org/ontology/MESH/C536649 http://homosaurus.org/v2/aphallia aphallia https://en.wikipedia.org/wiki/Aphallia https://www.wikidata.org/wiki/Q4779465 congenital absence and aplasia of penis Q55.5 The marketing and advertising of pharmaceutical products or medical devices directly to consumers as patients, as opposed to specifically targeting health professionals. https://en.wikipedia.org/wiki/Direct-to-consumer_advertising https://www.wikidata.org/wiki/Q65088823 direct-to-consumer advertising DTCA http://purl.bioontology.org/ontology/MESH/D000067088 Document or chart that shows days, weeks, and months of a year. calendar calendars 529.3 529.3 20 A state of physical, emotional, mental and social well-being in relation to sexuality. https://en.wikipedia.org/wiki/Category:Sexual_health sexual health http://homosaurus.org/v2/sexualHealth http://purl.bioontology.org/ontology/MESH/D000074384 http://homosaurus.org/v2/sexualHealth A civilization of ancient Northeastern Africa, concentrated along the lower reaches of the Nile River in the area of Egypt. It was active from 3100 B.C. until its conquest by Alexander the Great in 332 B.C. https://en.wikipedia.org/wiki/Ancient_Egypt Egypt, Ancient ancient Egypt Ancient Egypt 3100 BCE 332 BCE Ancient Egyptian http://purl.bioontology.org/ontology/MESH/D000076144 Ancient Egyptian Ancient Egyptians A civilization extant from about 1200 BC. to the death of Alexander the Great, in 323 B.C. It extended from the Greek city states to North Africa and eastward to the Indus River. https://en.wikipedia.org/wiki/Ancient_Greece Greece, Ancient ancient Greece Ancient Greece 1200 BCE 323 BCE Ancient Greek http://purl.bioontology.org/ontology/MESH/D000076145 Ancient Greek Ancient Greeks Ability to connect to the internet and access services available there. https://en.wikipedia.org/wiki/Internet_access internet access Connectivity facilitated by computer-based communications among persons with family, work, or other common interests. online social networking A reference book containing a list of words related to medicine-usually in alphabetic order-giving information about form, pronunciation, etymology, grammar, and meaning. medical dictionary medical dictionaries Process of increasing the capacity of individuals or groups to make choices and to transform those choices into desired actions as deigned by the individuals or groups. https://en.wikipedia.org/wiki/Empowerment https://www.wikidata.org/wiki/Q868575 empowerment http://purl.bioontology.org/ontology/MESH/D000079102 A group of inherited conditions of the adrenal glands, caused by enzyme defects in the synthesis of cortisol (hydrocortisone) and/or aldosterone leading to accumulation of precursors for androgens. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in steroid 21-hydroxylase; steroid 11-beta-hydroxylase; steroid 17-alpha-hydroxylase; 3-beta-hydroxysteroid dehydrogenase (3-hydroxysteroid dehydrogenases); testosterone 5-alpha-reductase; or steroidogenic acute regulatory protein; among others, underlie these conditions. https://en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia https://www.wikidata.org/wiki/Q366868 congenital adrenal gland hyperplasia congenital adrenal hyperplasia congenital adrenal hyperplasias http://homosaurus.org/v2/congenitalAdrenalHyperplasia 255.2 http://purl.obolibrary.org/obo/NCIT_C34360 CAH http://purl.bioontology.org/ontology/MEDDRA/10010323 http://purl.obolibrary.org/obo/HP_0008258 E25.0 http://purl.bioontology.org/ontology/MESH/D000312 http://purl.bioontology.org/ontology/SNOMEDCT/237751000 http://purl.obolibrary.org/obo/DOID_0050811 http://homosaurus.org/v2/congenitalAdrenalHyperplasia A marketing communication that employs an openly sponsored, non-personal message to promote or sell a product, service or idea. https://en.wikipedia.org/wiki/Advertising https://en.wikipedia.org/wiki/Category:Advertising https://www.wikidata.org/wiki/Q37038 advertising http://id.loc.gov/authorities/subjects/sh85001086 HF5801-HF6182 http://purl.bioontology.org/ontology/MESH/D000329 A chemical compound with the formula C5H11ONO. A variety of isomers are known, but they all feature an amyl group attached to the nitrite functional group. The alkyl group is unreactive and the chemical and biological properties are mainly due to the nitrite group. Like other alkyl nitrites, amyl nitrite is bioactive in mammals, being a vasodilator, which is the basis of its use as a prescription medicine. As an inhalant, it also has a psychoactive effect, which has led to its recreational use with its smell being described as that of old socks or dirty feet.[1] It is also referred to as banapple gas. A vasodilator that is administered by inhalation. It is also used recreationally due to its supposed ability to induce euphoria and act as an aphrodisiac. https://en.wikipedia.org/wiki/Amyl_nitrite https://www.wikidata.org/wiki/Q27888090 amyl nitrite http://purl.obolibrary.org/obo/NCIT_C87278 http://purl.bioontology.org/ontology/MESH/D000680 http://purl.bioontology.org/ontology/SNOMEDCT/387038004 A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. Any agent capable of having a stimulating effect on the central nervous system. https://en.wikipedia.org/wiki/Category:Stimulants https://en.wikipedia.org/wiki/Stimulant https://www.wikidata.org/wiki/Q211036 psychostimulant central nervous system stimulant central nervous system stimulants http://id.loc.gov/authorities/subjects/sh85128149 RM332-RM332.3 http://purl.obolibrary.org/obo/NCIT_C47795 CNS stimulant stimulant http://purl.bioontology.org/ontology/MESH/D000697 http://purl.bioontology.org/ontology/SNOMEDCT/373333006 CNS stimulant CNS stimulants stimulant stimulants psychostimulant psychostimulants http://purl.bioontology.org/ontology/SNOMEDCT/387459000 Anxiety due to fantasized injuries to or loss of the genitals. https://en.wikipedia.org/wiki/Castration_anxiety https://www.wikidata.org/wiki/Q1735503 castration anxiety http://purl.bioontology.org/ontology/MESH/D001009 A geographical area of the United States with no definite boundaries but comprising northeastern Alabama, northwestern Georgia, northwestern South Carolina, western North Carolina, eastern Kentucky, eastern Tennessee, western Virginia, West Virginia, western Maryland, southwestern Pennsylvania, southern Ohio, and southern New York. Appalachian Region http://purl.bioontology.org/ontology/MESH/D001061 A diverse range of human activities in creating visual, auditory or performing artifacts (artworks), expressing the author's imaginative, conceptual ideas, or technical skill, intended to be appreciated for their beauty or emotional power. https://en.wikipedia.org/wiki/Art https://en.wikipedia.org/wiki/Category:Arts the arts art arts http://id.loc.gov/authorities/subjects/sh85008324 700 http://purl.bioontology.org/ontology/MESH/D001154 art art the arts https://en.wikipedia.org/wiki/The_arts 700 23 Knowing that something exists, or having knowledge or experience of a particular thing; having special interest in or experience of something and so being well informed of what is happening in that subject at the present time. aware awareness http://id.loc.gov/authorities/subjects/sh85010576 http://purl.bioontology.org/ontology/MESH/D001364 An infection caused by a bacterium. bacterial infection bacterial infections The observable response an animal makes to any situation. https://www.wikidata.org/wiki/Q2990593 animal behaviour animal behavior animal behaviors http://id.loc.gov/authorities/subjects/sh85005162 591.5 591.51 QL750-QL782.5 http://purl.bioontology.org/ontology/MESH/D001522 animal behaviour animal behaviours 591.5 22 591.51 20 The capital of Germany. http://purl.obolibrary.org/obo/GAZ_00003510 https://en.wikipedia.org/wiki/Berlin https://en.wikipedia.org/wiki/Category:Berlin https://www.wikidata.org/wiki/Q64 City of Berlin Berlin http://purl.bioontology.org/ontology/MESH/D001604 The mass or quantity of heaviness of an individual at birth. It is expressed by units of pounds or kilograms. https://en.wikipedia.org/wiki/Birth_weight https://www.wikidata.org/wiki/Q4128476 birth-weight birthweight weight at birth birth weight birth weights http://id.loc.gov/authorities/subjects/sh85014389 http://purl.bioontology.org/ontology/MESH/D001724 The distance from the sole to the crown of the head with body standing on a flat surface and fully extended. http://www.ebi.ac.uk/efo/EFO_0004339 body height body heights http://purl.obolibrary.org/obo/NCIT_C164634 http://purl.bioontology.org/ontology/MEDDRA/10005891 http://purl.bioontology.org/ontology/MESH/D001827 The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. http://www.ebi.ac.uk/efo/EFO_0004338 body weight body weights http://id.loc.gov/authorities/subjects/sh85015259 http://purl.obolibrary.org/obo/NCIT_C81328 http://purl.bioontology.org/ontology/MESH/D001835 http://purl.bioontology.org/ontology/SNOMEDCT/27113001 A state on the western coast of the United States. Its capital is Sacramento. State bounded on the east by Nevada and Arizona, on the south by Mexico and the Pacific Ocean on the south and west, and on the north by Oregon. State of California California Californian http://purl.obolibrary.org/obo/NCIT_C43509 http://purl.bioontology.org/ontology/MESH/D002140 http://purl.bioontology.org/ontology/SNOMEDCT/224043007 Californian Californians A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. agent affecting nervous system central nervous system agent central nervous system drug central nervous system drugs http://purl.obolibrary.org/obo/NCIT_C78272 http://purl.bioontology.org/ontology/MESH/D002491 http://purl.bioontology.org/ontology/SNOMEDCT/372752008 agent affecting nervous system agents affecting nervous system central nervous system agent central nervous system agents A large or important municipality of a country, usually a major metropolitan center. city cities http://purl.bioontology.org/ontology/MESH/D002947 The sexual union of a male and a female, a term used for human only. coetus coital This term refers only to penile-vaginal penetration in humans in which sperm is transferred. coitus coituses E1.0.0.0.0.0.9 http://purl.bioontology.org/ontology/MESH/D003075 coitus A birth control method adopted during sexual intercourse by withdrawing the penis from the vagina before ejaculation. A contraceptive method whereby coitus is purposely interrupted in order to prevent ejaculation of semen into the vagina. https://en.wikipedia.org/wiki/Coitus_interruptus https://www.wikidata.org/wiki/Q182207 French method contraceptive coitus interruptus interrupted coitus pull-out method pulling out rejected sexual intercourse withdrawal contraception withdrawal contraceptive method withdrawal method coitus interruptus http://id.loc.gov/authorities/subjects/sh85027883 http://purl.bioontology.org/ontology/MEDDRA/10066230 http://purl.bioontology.org/ontology/MESH/D003076 http://purl.bioontology.org/ontology/SNOMEDCT/169513000 contraceptive coitus interruptus http://purl.bioontology.org/ontology/SNOMEDCT/169513000 withdrawal contraception http://purl.obolibrary.org/obo/NCIT_C92919 Those factors, such as language or sociocultural relationships, which interfere in the meaningful interpretation and transmission of ideas between individuals or groups. language barrier communication barrier communication barriers language barrier Linguistic barriers to communication, i.e. the difficulties in communication experienced by people or groups speaking different languages, or even dialects in some cases. https://en.wikipedia.org/wiki/Language_barrier https://www.wikidata.org/wiki/Q2588869 language barriers A system containing any combination of computers, computer terminals, printers, audio or visual display devices, or telephones interconnected by telecommunications equipment or cables: used to transmit or receive information. distributed system computer communication network computer communication networks http://purl.bioontology.org/ontology/MESH/D003195 A clash of interest. The basis of conflict may vary but, it is always a part of society. Basis of conflict- personal, racial, class, caste, political and international. Conflict in groups often follows a specific course. https://en.wikipedia.org/wiki/Conflict_(process) conflict (psychology) intrapsychic conflict conflict conflīctus An act which constitutes the termination of a given instinctive behavior pattern or sequence. consummatory behavior consummatory behaviors Prevention of conception by blocking fertility temporarily, or permanently. Common means of reversible contraception include natural family planning methods; contraceptive agents; or contraceptive devices. The prevention of conception or impregnation by the use of devices or drugs or surgery. https://www.wikidata.org/wiki/Q122224 contraception NOS contraceptive contraception http://id.loc.gov/authorities/subjects/sh85031589 RG136-RG137.6 http://purl.obolibrary.org/obo/NCIT_C37932 http://purl.bioontology.org/ontology/MEDDRA/10010808 http://purl.bioontology.org/ontology/MESH/D003267 http://purl.bioontology.org/ontology/SNOMEDCT/13197004 contraception NOS http://purl.bioontology.org/ontology/MEDDRA/10010809 The giving of advice and assistance to individuals with educational or personal problems. https://en.wikipedia.org/wiki/Category:Counseling counseling intervention counseling service counseling http://id.loc.gov/authorities/subjects/sh85033421 BF636.5-BF636.7 http://purl.bioontology.org/ontology/MESH/D003376 http://purl.bioontology.org/ontology/SNOMEDCT/409063005 counseling intervention counseling interventions counseling service counseling services A superfamily of hundreds of closely related hemeproteins found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (mixed function oxygenases). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (biotransformation). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. cytochrome P450 dependent monooxygenase cytochrome P450 dependent monooxygenases http://purl.bioontology.org/ontology/MESH/D003577 Created as a republic in 1918 by Czechs and Slovaks from territories formerly part of the Austro-Hungarian Empire. The country split into the Czech Republic and Slovakia 1 January 1993. https://en.wikipedia.org/wiki/Czechoslovakia Czecho-Slovakia Czechoslovakia 1992-12-31T00:00:00 Czechoslovak http://purl.bioontology.org/ontology/MESH/D003604 Czechoslovak Czechoslovaks Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases. https://en.wikipedia.org/wiki/Category:DNA-binding_proteins https://en.wikipedia.org/wiki/DNA-binding_protein https://www.wikidata.org/wiki/Q2252764 DNA binding protein DNA-binding protein DNA-binding proteins http://purl.obolibrary.org/obo/NCIT_C16518 http://purl.bioontology.org/ontology/MESH/D004268 DNA binding protein DNA binding proteins A state of internal activity of an organism that is a necessary condition before a given stimulus will elicit a class of responses; e.g., a certain level of hunger (drive) must be present before food will elicit an eating response. drive drives dráf dríf-an http://purl.bioontology.org/ontology/SNOMEDCT/247750002 The use of drugs to treat a disease or its symptoms; or to aid in alleviating any of other various problems,, issues, or conditions. One example is the use of antineoplastic agents to treat cancer. pharmacotherapy drug therapy drug therapies http://purl.obolibrary.org/obo/NCIT_C15986 http://purl.bioontology.org/ontology/MEDDRA/10063370 http://purl.bioontology.org/ontology/MESH/D004358 http://purl.bioontology.org/ontology/SNOMEDCT/416608005 pharmacotherapy pharmacotherapies Education and training outside that for the professions. non-professional education nonprofessional education http://purl.bioontology.org/ontology/MESH/D004505 A country in North Africa that includes the Sinai Peninsula, a land bridge to Asia. Egypt borders Libya to the west, Sudan to the south, and the Gaza Strip and Israel to the east. The northern coast borders the Mediterranean Sea and the island of Cyprus; the eastern coast borders the Red Sea. Egypt is divided into 26 governorates (in Arabic, called muhafazat, singular muhafazah). The governorates are further divided into regions (markazes). https://en.wikipedia.org/wiki/Category:Egypt https://en.wikipedia.org/wiki/Egypt https://www.wikidata.org/wiki/Q79 Egypt Egyptian http://purl.obolibrary.org/obo/NCIT_C16530 http://purl.bioontology.org/ontology/MESH/D004534 http://purl.bioontology.org/ontology/SNOMEDCT/223511009 Egyptian Egyptians One of several substances made in the body that can relieve pain and give a feeling of well-being. Endorphins are peptides (small proteins) that bind to opioid receptors in the central nervous system. An endorphin is a type of neurotransmitter. One of the three major groups of endogenous opioid peptides. They are large peptides derived from the pro-opiomelanocortin precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; opioid peptides is used for the broader group. https://en.wikipedia.org/wiki/Endorphins https://www.wikidata.org/wiki/Q190528 endorphin endorphins http://purl.obolibrary.org/obo/NCIT_C469 http://purl.bioontology.org/ontology/MESH/D004723 http://purl.bioontology.org/ontology/SNOMEDCT/53682000 Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however catalytic RNA and catalytic DNA molecules have also been identified. http://purl.bioontology.org/ontology/STY/T126 http://purl.obolibrary.org/obo/OBI_0000427 https://en.wikipedia.org/wiki/Category:Enzymes https://en.wikipedia.org/wiki/Enzyme https://www.wikidata.org/wiki/Q8047 enzyme enzymes http://purl.obolibrary.org/obo/NCIT_C16554 http://purl.bioontology.org/ontology/MESH/D004798 http://purl.bioontology.org/ontology/SNOMEDCT/734543001 A branch of philosophy that deals with the nature of art, beauty and taste. It examines subjective and sensori-emotional values, or sometimes called judgments of sentiment and taste. https://en.wikipedia.org/wiki/Aesthetics https://en.wikipedia.org/wiki/Category:Aesthetics aesthetic esthetic aesthetics http://id.loc.gov/authorities/subjects/sh85001441 BH N61-N79 http://purl.bioontology.org/ontology/MESH/D004954 State bounded on east by the Atlantic Ocean, on the south by the Gulf of Mexico, on the west by Alabama and on the north by Alabama and Georgia. https://en.wikipedia.org/wiki/Category:Florida https://en.wikipedia.org/wiki/Florida https://www.wikidata.org/wiki/Q812 State of Florida Florida Floridan Floridian http://purl.obolibrary.org/obo/NCIT_C43478 http://purl.bioontology.org/ontology/MESH/D005431 http://purl.bioontology.org/ontology/SNOMEDCT/224048003 Floridan Floridans Floridian Floridians The period of the menstrual cycle representing follicular growth, increase in ovarian estrogen (estrogens) production, and epithelial proliferation of the endometrium. Follicular phase begins with the onset of menstruation and ends with ovulation. estrogenic phase proliferative phase follicular phase E1.0.2.3.0.0.4 estrogenic phase oestrogenic phase A person's concept of self as being male and masculine or female and feminine, or ambivalent, based in part on physical characteristics, parental responses, and psychological and social pressures. It is the internal experience of gender role. A person's sense of self as a member of a particular gender. sex identity https://en.wikipedia.org/wiki/Category:Gender_identity https://en.wikipedia.org/wiki/Gender_identity self-identified gender identity gender identity datum gender identity finding gender identity information content entity core gender identity Note that while current models of gender support the idea that children categorize their own gender by around 3-6 years of age, personal conceptualization of gender identity can shift throughout a person's life (even within an individual category). Persons may identify with one, many, or no gender categories; additionally, pronoun use is not necessarily connected to gender identity. gender identity gender identities http://homosaurus.org/v2/genderIdentity http://id.loc.gov/authorities/subjects/sh91003756 HQ18.55-HQ18.552 http://purl.obolibrary.org/obo/NCIT_C158277 GI http://purl.bioontology.org/ontology/MESH/D005783 sex identity sex identities self-identified gender identity A person may self-identify as something other than their true gender identity for any of various reasons; therefore, sometimes it is more accurate to include "self-identified gender identity" rather than "gender identity", but in practice these values may be essentially synonymous. self-identified gender identities SIGI gender identity datum http://purl.obolibrary.org/obo/OMRSE_00000133 gender identity data gender identity finding genderr identity findings http://purl.bioontology.org/ontology/SNOMEDCT/285116001 gender identity information content entity http://purl.obolibrary.org/obo/OMRSE_00000209 This represents an information entity which is identification as a certain gender in some context. This datum may not represent a person's actual gender identity. For instance, if an individual has an online persona in which they identify as another gender, or if they lie (for instance, it may be safer for a pre-transition transgender person to lie about their gender identity in some contexts). gender identity information content entities core gender identity CGI http://homosaurus.org/v2/genderIdentity An educational process that provides information and advice to individuals or families about a genetic condition that may affect them. The purpose is to help individuals make informed decisions about marriage, reproduction, and other health management issues based on information about the genetic disease, the available diagnostic tests, and management programs. Psychosocial support is usually offered. https://en.wikipedia.org/wiki/Genetic_counseling https://www.wikidata.org/wiki/Q1124169 genetic counseling V26.33 http://purl.obolibrary.org/obo/NCIT_C15240 http://purl.bioontology.org/ontology/MEDDRA/10018138 http://purl.bioontology.org/ontology/MESH/D005817 http://purl.bioontology.org/ontology/SNOMEDCT/79841006 The former German Democratic Republic which was reunified with the former Federal Republic of Germany in 1990. https://en.wikipedia.org/wiki/East_Germany East Germany 1949 1990 East German http://purl.bioontology.org/ontology/MESH/D005859 East German East Germans The former Federal Republic of Germany which was reunified with the former German Democratic Republic in 1990. https://en.wikipedia.org/wiki/West_Germany West Germany 1949 1990 943.087 West German http://purl.bioontology.org/ontology/MESH/D005860 943.087 20 West German West Germans Any of various conditions which feature streak gonads, dysgenetic testes, or dysgenetic ovaries. https://en.wikipedia.org/wiki/Gonadal_dysgenesis https://www.wikidata.org/wiki/Q1332427 gonadal dysgenesis NOS gonadal dysgenesis syndrome gonadal dysgenesia gonadal dysgenesis http://homosaurus.org/v2/gonadalDysgenesis 758.6 http://purl.obolibrary.org/obo/NCIT_C61420 http://purl.bioontology.org/ontology/MEDDRA/10018504 http://purl.obolibrary.org/obo/HP_0000133 Q96.9 http://purl.bioontology.org/ontology/SNOMEDCT/205681004 http://purl.obolibrary.org/obo/DOID_14447 http://homosaurus.org/v2/gonadalDysgenesis A type of gonadal dysgenesis resulting from any of various chromosomal mosaicisms. mixed partial gonadal dysgenesis partial gonadal dysgenesis mixed gonadal dysgenesis MGD Q96.9 http://purl.bioontology.org/ontology/MESH/D006060 http://purl.bioontology.org/ontology/SNOMEDCT/83579008 http://purl.obolibrary.org/obo/DOID_14449 Hormones secreted by the adenohypophysis (pituitary gland, anterior) that stimulate gonadal functions in both males and females. They include follice stimulating hormone that stimulates germ cell maturation (oogenesis; spermatogenesis), and luteinizing hormone that stimulates the production of sex steroids (estrogens; progesterone; androgens). pituitary gonadotropin pituitary gonadotropins http://purl.bioontology.org/ontology/MESH/D006065 The geographic area of the Great Lakes in general and when the specific state or states are not indicated. It usually includes Illinois, Indiana, Michigan, Minnesota, New York, Ohio, Pennsylvania, and Wisconsin. Great Lakes Region http://purl.bioontology.org/ontology/MESH/D006114 Medical problems that affect a person's growth or otherwise present growth-related symptoms. https://en.wikipedia.org/wiki/Category:Growth_disorders growth disorder growth disorders Education that increases the awareness and favorably influences the attitudes and knowledge relating to the improvement of health on a personal or community basis. https://en.wikipedia.org/wiki/Category:Health_education https://en.wikipedia.org/wiki/Health_education https://www.wikidata.org/wiki/Q60894 health education http://purl.obolibrary.org/obo/NCIT_C16664 http://purl.bioontology.org/ontology/MESH/D006266 Bleeding or escape of blood from a vessel. The flow of blood from a ruptured blood vessel. https://en.wikipedia.org/wiki/Bleeding https://en.wikipedia.org/wiki/Category:Bleeding https://www.wikidata.org/wiki/Q166019 bleeding hemorrhage hemorrhages http://id.loc.gov/authorities/subjects/sh85060224 RB144 RD33.3 http://purl.obolibrary.org/obo/NCIT_C26791 http://purl.bioontology.org/ontology/MEDDRA/10005103 http://purl.bioontology.org/ontology/MEDDRA/10055798 http://purl.bioontology.org/ontology/MESH/D006470 http://purl.bioontology.org/ontology/SNOMEDCT/131148009 Excess blood loss from uterine bleeding associated with obstetric labor or childbirth. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as blood pressure and hematocrit. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum). https://en.wikipedia.org/wiki/Postpartum_bleeding https://www.wikidata.org/wiki/Q2916482 postpartum hemorrhage postpartum hemorrhage http://purl.obolibrary.org/obo/NCIT_C92853 PPH http://purl.bioontology.org/ontology/MESH/D006473 Record and study of past events. https://en.wikipedia.org/wiki/Category:History https://en.wikipedia.org/wiki/History history http://id.loc.gov/authorities/subjects/sh85061212 900 D http://purl.obolibrary.org/obo/NCIT_C54625 http://purl.bioontology.org/ontology/MESH/D006664 900 23 Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (coenzymes) required in the mixed-function oxidation. https://en.wikipedia.org/wiki/Monooxygenase https://www.wikidata.org/wiki/Q6901821 mixed-function oxygenase monooxygenase mixed function oxygenase mixed function oxygenases http://purl.bioontology.org/ontology/MESH/D006899 http://purl.bioontology.org/ontology/SNOMEDCT/129923001 http://purl.bioontology.org/ontology/SNOMEDCT/423265008 mixed-function oxygenase mixed-function oxygenases monooxygenase monooxygenases An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement. hyperplasia NOS hyperplasia http://purl.obolibrary.org/obo/NCIT_C3113 http://purl.bioontology.org/ontology/MEDDRA/10020718 http://purl.bioontology.org/ontology/MESH/D006965 http://purl.bioontology.org/ontology/SNOMEDCT/76197007 hyperplasia NOS http://purl.bioontology.org/ontology/MEDDRA/10020726 Abnormal enlargement of a body part or organ. hypertrophy hypertrophies http://purl.obolibrary.org/obo/NCIT_C3124 http://purl.bioontology.org/ontology/MEDDRA/10020880 http://purl.bioontology.org/ontology/MESH/D006984 http://purl.bioontology.org/ontology/SNOMEDCT/56246009 A congenital abnormality in which the external urethral orifice is on the underside of the penis. In a minority of cases it is associated with other genitourinary abnormalities. hypospadias and epispadias and other penile anomalies https://en.wikipedia.org/wiki/Hypospadias hypospadias with intersex state hypospadias, unspecified other hypospadias hypospadia hypospadias http://homosaurus.org/v2/hypospadias 752.61 http://purl.obolibrary.org/obo/NCIT_C40341 http://purl.bioontology.org/ontology/MEDDRA/10021093 http://purl.obolibrary.org/obo/HP_0000047 Q54 http://purl.bioontology.org/ontology/MESH/D007021 hypo- http://purl.bioontology.org/ontology/SNOMEDCT/416010008 http://purl.obolibrary.org/obo/DOID_10892 hypospadias and epispadias and other penile anomalies 752.6 hypospadias, unspecified Q54.9 other hypospadias Q54.8 http://homosaurus.org/v2/hypospadias A child between 1 and 23 months of age. infant infants E1.0.2.7.0.0.5 http://purl.bioontology.org/ontology/MESH/D007223 Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it. Intramuscular injection is a route of drug administration via injection into muscle tissue. Aqueous or oleaginous solutions and emulsions or suspensions may be administered. Absorption rates, delay in availability of the drug to the systemic circulation, and duration of effect are perfusion-limited, depend on molecular size of the agent, volume, and osmolarity of the drug solution, fat content of the injection site, and patient physical activity. intramuscular route of administration intramuscular injection intramuscular injections http://purl.bioontology.org/ontology/MEDDRA/10082261 http://purl.bioontology.org/ontology/MESH/D007273 http://purl.bioontology.org/ontology/SNOMEDCT/76601001 Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin. Subcutaneous injections are administered into the subcutis, the layer of skin directly below the cutis (the dermis and epidermis collectively). subcutaneous injection subcutaneous injections http://purl.bioontology.org/ontology/MESH/D007279 http://purl.bioontology.org/ontology/SNOMEDCT/32282008 The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions. https://en.wikipedia.org/wiki/Intelligence intelligent intelligence intellegentia intelligence The set of symptoms that result from two or more X chromosomes in males. The primary features are infertility and small testicles. Often, symptoms may be subtle and many people do not realize they are affected. Sometimes, symptoms are more prominent and may include weaker muscles, greater height, poor coordination, less body hair, breast growth, and less interest in sex. 101500 http://homosaurus.org/v2/klinefelterSyndrome Klinefelter syndrome, male with more than two X chromosomes Klinefelter syndrome, unspecified Klinefelter's syndrome Klinefelter syndrome Klinefelter syndromes http://id.loc.gov/authorities/subjects/sh85072641 RC882 758.7 http://purl.obolibrary.org/obo/NCIT_C34752 KS http://purl.bioontology.org/ontology/MESH/D007713 http://purl.bioontology.org/ontology/SNOMEDCT/22053006 http://purl.obolibrary.org/obo/DOID_1921 101500 http://homosaurus.org/v2/klinefelterSyndrome Klinefelter syndrome, male with more than two X chromosomes Q98.1 Klinefelter syndrome, unspecified Q98.4 Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge. https://en.wikipedia.org/wiki/Learning https://www.wikidata.org/wiki/Q133500 learn learned learns learning http://id.loc.gov/authorities/subjects/sh85075520 LB1060 http://purl.bioontology.org/ontology/MESH/D007858 leornian http://purl.obolibrary.org/obo/GO_0007612 The science of language, including phonetics, phonology, morphology, syntax, semantics, pragmatics, and historical linguistics. https://en.wikipedia.org/wiki/Category:Linguistics https://en.wikipedia.org/wiki/Linguistics https://www.wikidata.org/wiki/Q8162 linguistic linguistic science science of language linguistics http://id.loc.gov/authorities/subjects/sh85077222 410 P121-P158.42 -ic linguist linguistic 410 23 Writings having excellence of form or expression and expressing ideas of permanent or universal interest. The body of written works produced in a particular language, country, or age. other literature belles-lettres literary work world literature literature literatures http://id.loc.gov/authorities/subjects/sh85077507 800 PN45 http://purl.bioontology.org/ontology/MESH/D008091 other literature other literatures belles-lettres https://en.wikipedia.org/wiki/Belles-lettres belles lettres literary work literary works world literature Used to refer to the total of the world's national literature and the circulation of works into the wider world beyond their country of origin. In the past, it primarily referred to the masterpieces of Western European literature; however, world literature today is increasingly seen in an international context. Now, readers have access to a wide range of global works in various translations. world literatures 800 23 The period in the menstrual that follows ovulation, characterized by the development of corpus luteum, increase in progesterone production by the ovary and secretion by the glandular epithelium of the endometrium. The luteal phase begins with ovulation and ends with the onset of menstruation. progesterone phase secretory phase luteal phase E1.0.2.3.0.0.6 State bounded on the north by New Hampshire and Vermont, on the east by the Atlantic Ocean, on the south by Connecticut and Rhode Island, and on the west by New York. https://en.wikipedia.org/wiki/Category:Massachusetts https://en.wikipedia.org/wiki/Massachusetts https://www.wikidata.org/wiki/Q771 Commonwealth of Massachusetts State of Massachusetts Massachusetts Massachusite http://purl.obolibrary.org/obo/NCIT_C43463 http://purl.bioontology.org/ontology/MESH/D008404 http://purl.bioontology.org/ontology/SNOMEDCT/224066008 Massachusite Massachusites The premature cessation of menses when the last menstrual period occurs in a woman under the age of 40. It is due to the depletion of ovarian follicles. Premature menopause can be caused by diseases; ovariectomy; radiation; chemicals; and chromosomal abnormalities. premature menopause http://purl.bioontology.org/ontology/MESH/D008594 The normal physiologic discharge through the vagina of blood and mucosal tissues from the nonpregnant uterus. The periodic shedding of the endometrium and associated menstrual bleeding in the menstrual cycle of humans and primates. Menstruation is due to the decline in circulating progesterone, and occurs at the late luteal phase when luteolysis of the corpus luteum takes place. https://en.wikipedia.org/wiki/Menstruation https://en.wikipedia.org/wiki/Menstruation_(mammal) https://www.wikidata.org/wiki/Q12171 menstruate menstruated menstruates menstruating desquamation phase menstrual menstrual period menstrual phase menstruation menstruations 612.662 618.172 E1.0.2.3.0.0.9 http://purl.obolibrary.org/obo/NCIT_C3232 http://purl.obolibrary.org/obo/GO_0042703 612.662 human physiology 20 618.172 gynecology 20 Emotional, psychological, and social well-being of an individual or group. The overall state of an individual's psychologic constitution. https://en.wikipedia.org/wiki/Category:Mental_health https://en.wikipedia.org/wiki/Mental_health https://www.wikidata.org/wiki/Q317309 mental health http://id.loc.gov/authorities/subjects/sh85083615 RA790-RA790.95 http://purl.obolibrary.org/obo/NCIT_C93187 http://purl.bioontology.org/ontology/MESH/D008603 Organized services to provide mental health care. mental health service mental health services http://purl.bioontology.org/ontology/MESH/D008605 The branch of philosophy that examines the fundamental nature of reality, including the relationship between mind and matter, between substance and attribute, and between potentiality and actuality. https://en.wikipedia.org/wiki/Category:Metaphysics https://en.wikipedia.org/wiki/Metaphysics https://www.wikidata.org/wiki/Q35277 metaphysics http://id.loc.gov/authorities/subjects/sh85084286 110 BD http://purl.bioontology.org/ontology/MESH/D008678 110 23 A geographical area of the United States comprising the District of Columbia, Delaware, Maryland, New Jersey, New York, and Pennsylvania. Mid-Atlantic Region http://purl.bioontology.org/ontology/MESH/D008873 The region of southwest Asia and northeastern Africa usually considered as extending from Libya on the west to Afghanistan on the east. Africa and the Middle East https://en.wikipedia.org/wiki/Category:Middle_East https://en.wikipedia.org/wiki/Middle_East https://www.wikidata.org/wiki/Q7204 the Middle East Middle East http://id.loc.gov/authorities/subjects/sh85090501 Middle Eastern http://purl.obolibrary.org/obo/NCIT_C26336 http://purl.bioontology.org/ontology/MESH/D008877 Africa and the Middle East The reason for people's actions, willingness and goals. https://en.wikipedia.org/wiki/Motivation motivate motivated motivates motivating motivation motivations http://id.loc.gov/authorities/subjects/sh85087562 -ation Motivierung motive Peptides released by neurons as intercellular messengers. Many neuropeptides are also hormones released by non-neuronal cells. https://en.wikipedia.org/wiki/Category:Neuropeptides https://en.wikipedia.org/wiki/Neuropeptide https://www.wikidata.org/wiki/Q419968 neuropeptide neuropeptides http://purl.bioontology.org/ontology/MESH/D009479 The geographic area of New England in general and when the specific state or states are not indicated. States usually included in this region are Maine, New Hampshire, Vermont, Massachusetts, Connecticut, and Rhode Island. New England http://purl.bioontology.org/ontology/MESH/D009511 A state in the northeastern United States. Its capital is Albany. State bounded on the north by Lake Ontario and Canada, on the east by Vermont, Massachusetts, and Connecticut, on the south by the Atlantic Ocean, New Jersey, and Pennsylvania, and on the west by Pennsylvania, Lake Erie, and Canada. https://en.wikipedia.org/wiki/New_York_(state) https://www.wikidata.org/wiki/Q1384 State of New York New York New Yorker http://purl.obolibrary.org/obo/NCIT_C43468 http://purl.bioontology.org/ontology/MESH/D009518 http://purl.bioontology.org/ontology/SNOMEDCT/420278009 New Yorker New Yorkers City located at the mouth of the Hudson River, in New York State. New York City, NY New York City, New York New York City NYC http://purl.bioontology.org/ontology/MESH/D009519 Transmission of emotions, ideas, and attitudes between individuals in ways other than the spoken language. https://en.wikipedia.org/wiki/Nonverbal_communication https://www.wikidata.org/wiki/Q207125 non-verbal communication nonverbal communication NVC The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. https://en.wikipedia.org/wiki/Category:Oxidoreductases https://en.wikipedia.org/wiki/Oxidoreductase https://www.wikidata.org/wiki/Q407479 oxidoreductase oxidoreductases http://purl.obolibrary.org/obo/NCIT_C16946 http://purl.bioontology.org/ontology/MESH/D010088 http://purl.bioontology.org/ontology/SNOMEDCT/68101005 http://enzyme.expasy.org/EC/1.-.-.- Oxidases that specifically introduce dioxygen-derived oxygen atoms into a variety of organic molecules. https://en.wikipedia.org/wiki/Category:Oxygenases https://en.wikipedia.org/wiki/Oxygenase https://www.wikidata.org/wiki/Q419615 oxidoreductase acting on a single donor with incorporation of molecular oxygen oxygenase oxygenases http://purl.obolibrary.org/obo/NCIT_C28459 http://purl.bioontology.org/ontology/MESH/D010105 http://purl.bioontology.org/ontology/SNOMEDCT/129922006 https://enzyme.expasy.org/EC/1.13.-.- https://enzyme.expasy.org/EC/1.14.-.- oxidoreductase acting on a single donor with incorporation of molecular oxygen oxidoreductases acting on single donors with incorporation of molecular oxygen The study of general and fundamental questions about existence, knowledge, values, reason, mind, and language. https://en.wikipedia.org/wiki/Philosophy philosophy philosophies http://id.loc.gov/authorities/subjects/sh85100849 100 B-BJ http://purl.obolibrary.org/obo/NCIT_C39794 http://purl.bioontology.org/ontology/MESH/D010684 philosophia philosophie 100 23 The science or study of speech sounds and their production, transmission, and reception, and their analysis, classification, and transcription. https://en.wikipedia.org/wiki/Phonetics https://www.wikidata.org/wiki/Q35395 phonetics http://id.loc.gov/authorities/subjects/sh85101053 P221-P240 Act of eliciting a response from a person or organism through physical contact. physical stimulation physical stimulations http://purl.obolibrary.org/obo/NCIT_C61406 stimulation The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (polymorphism, single nucleotide) to large nucleotide sequences visible at a chromosomal level. https://en.wikipedia.org/wiki/Category:Genetic_polymorphisms genetic polymorphism genetic polymorphisms http://id.loc.gov/authorities/subjects/sh85053865 polymorphism http://purl.bioontology.org/ontology/MESH/D011110 polymorphism polymorphisms A subjective and comparative term describing a lack of sufficient wealth (usually understood as capital, money, material goods, or resources especially natural resources) to live what is understood in a society as a "normal" life: for instance, to be capable of raising a healthy family, and especially educating children and participating in society. A person living in this condition of poverty is said to be poor. The meaning of "sufficient" varies widely across the different political and economic areas of the world. Not having enough material possessions or income for a person's needs. Poverty may include social, economic, and political elements. The inability to meet basic human needs, such as food, shelter, and avoidance of disease. https://en.wikipedia.org/wiki/Category:Poverty https://en.wikipedia.org/wiki/Poverty https://www.wikidata.org/wiki/Q10294 poverty status poverty http://id.loc.gov/authorities/subjects/sh85105939 HC79.P6 HV1-HV4630 http://purl.obolibrary.org/obo/NCIT_C17009 http://purl.bioontology.org/ontology/MEDDRA/10036465 http://purl.bioontology.org/ontology/MESH/D011203 Outcome of the process of increasing the capacity of individuals or groups to make choices and to transform those choices into desired actions as deigned by the individuals or groups. powerful power powers http://purl.bioontology.org/ontology/MESH/D011209 Performance of an act one or more times, with a view to its fixation or improvement; any performance of an act or behavior that leads to learning. practiced practicing practice practices Services designed for health promotion. prophylaxis preventive health service preventive health services http://purl.bioontology.org/ontology/MESH/D011314 prophylaxis prophylaxes Methods to avoid occurrence of disease either through eliminating disease agents or increasing resistance to disease. primary prevention E. Gurney Clark Hugh R. Leavell A person who is deprived of liberty against their will. This can be by confinement, captivity, or forcible restraint. The term applies particularly to serving a prison sentence in a prison. prisoners and detainees https://en.wikipedia.org/wiki/Prisoner https://www.wikidata.org/wiki/Q1862087 prison inmate prisoner prisoners http://id.loc.gov/authorities/subjects/sh85106950 http://purl.bioontology.org/ontology/MESH/D011329 prisoners and detainees https://en.wikipedia.org/wiki/Category:Prisoners_and_detainees prison inmate prison inmates Infections with unicellular organisms formerly members of the subkingdom Protozoa. protozoal infection protozoan infection protozoan infections http://purl.bioontology.org/ontology/MESH/D011528 protozoal infection infection protozoal protozoal infection NOS protozoal infections NEC protozoal infections A discipline concerned with relations between messages and the characteristics of individuals who select and interpret them; it deals directly with the processes of encoding (phonetics) and decoding (psychoacoustics) as they relate states of messages to states of communicators. https://en.wikipedia.org/wiki/Psycholinguistics https://www.wikidata.org/wiki/Q179488 psychology of language psycholinguistics http://id.loc.gov/authorities/subjects/sh85108432 BF455-BF463 P37-P37.5 A set of beliefs concerning the nature, cause, and purpose of the universe, especially when considered as the creation of a superhuman agency. It usually involves devotional and ritual observances and often a moral code for the conduct of human affairs. other religion comparative religion religions of the world religious studies world religion religion religions http://id.loc.gov/authorities/subjects/sh85112549 200 BL48-BL50 GN470-GN474 http://purl.obolibrary.org/obo/NCIT_C17085 http://purl.bioontology.org/ontology/MESH/D012067 other religion other religions comparative religion The branch of religious studies concerned with the systematic comparison of the similarities and differences in themes, myths, rituals and concepts of the religions of the world. https://en.wikipedia.org/wiki/Category:Comparative_religion https://en.wikipedia.org/wiki/Comparative_religion https://www.wikidata.org/wiki/Q1075827 religious studies https://en.wikipedia.org/wiki/Category:Religious_studies https://en.wikipedia.org/wiki/Religious_studies https://www.wikidata.org/wiki/Q34187 studies of religion study of religion world religion A category used in the study of religion to demarcate the five—and in some cases six—largest and most internationally widespread religious movements. Christianity, Islam, Judaism, Hinduism, and Buddhism are always included in the list, being known as the "Big Five". Some scholars also include another religion, such as Taoism, Sikhism, Zoroastrianism, or the Baháʼí Faith, in the category. These are often juxtaposed against other categories, such as "indigenous religions" and "new religious movements", which are also used by scholars in this field of research. https://en.wikipedia.org/wiki/World_religions https://www.wikidata.org/wiki/Q54073114 The world religions paradigm was developed in the United Kingdom in the 1960s, where it was pioneered by phenomenological scholars like Ninian Smart. It was designed to broaden the study of religion away from its heavy focus on Christianity by taking into account other large religious traditions around the world. The paradigm is often used by lecturers instructing undergraduate students in the study of religion and is also the framework used by school teachers in the UK and other countries. The paradigm's emphasis on viewing these religious movements as distinct and mutually exclusive entities has also had a wider impact on the categorisation of religion—for instance in censuses—in both Western countries and elsewhere. Since the late twentieth century, the paradigm has faced critique by scholars of religion like Jonathan Z. Smith, some of whom have argued for its abandonment. Critics have argued that the world religions paradigm is inappropriate because it takes the Protestant variant of Christianity as the model for what constitutes religion; that it is tied up with discourses of modernity, including modern power relations; that it encourages an uncritical understanding of religion; and that it makes a value judgement as to what religions should be considered "major". Others have argued that it remains useful in the classroom, so long as students are made aware that it is a socially constructed category. world religions 200 23 A monarchy located in north Asia bordering the Arctic Ocean, extending from Europe (the portion west of the Urals) to the North Pacific Ocean. St Petersburg was the capital 1712-1918. Moscow was the capital before St. Petersburg and following it. https://en.wikipedia.org/wiki/Russian_Empire Russian Empire 1721 1917 Russian Russia http://purl.bioontology.org/ontology/MESH/D012425 Russian Russians A city in northern California. City and County of San Francisco San Francisco, CA San Francisco, California San Francisco SF San Fran http://purl.bioontology.org/ontology/MESH/D012495 The meaning of a string in some language; of or relating to the study of meaning and changes of meaning. https://en.wikipedia.org/wiki/Semantics https://www.wikidata.org/wiki/Q39645 semasiology semantics http://id.loc.gov/authorities/subjects/sh85119870 P325 Advice and support given to individuals to help them understand and resolve their sexual adjustment problems. It excludes treatment for psychosexual disorders or psychosexual dysfunction. sex counseling, unspecified sex counseling http://id.loc.gov/authorities/subjects/sh85120571 HQ60.5-HQ60.7 http://purl.bioontology.org/ontology/MESH/D012731 sex counseling, unspecified Z70.9 The establishment of the sex of an organism by physical differentiation. The process in developing sex- or gender-specific tissue, organ, or function after sex determination processes have set the sex of the gonads. Major areas of sex differentiation occur in the reproductive tract (genitalia) and the brain. https://en.wikipedia.org/wiki/Sexual_differentiation sexual differentiation sex differentiation http://purl.bioontology.org/ontology/MESH/D012733 http://purl.obolibrary.org/obo/GO_0007548 Education which increases the knowledge of the functional, structural, and behavioral aspects of human sexual interaction. https://en.wikipedia.org/wiki/Category:Sex_education https://en.wikipedia.org/wiki/Sex_education https://www.wikidata.org/wiki/Q192280 family planning education reproductive health education sexual and reproductive health education sexual health education sex education http://homosaurus.org/v2/sexEducation http://purl.bioontology.org/ontology/MESH/D012736 http://homosaurus.org/v2/sexEducation Organic siloxanes which are polymerized to the oily stage. The oils have low surface tension and density less than 1. They are used in industrial applications and in the treatment of retinal detachment, complicated by proliferative vitreoretinopathy. https://en.wikipedia.org/wiki/Silicone_oil https://www.wikidata.org/wiki/Q416873 silicone oil silicone oils http://purl.bioontology.org/ontology/MESH/D012827 http://purl.bioontology.org/ontology/SNOMEDCT/108892002 Behavioral or attitudinal compliance with recognized social patterns or standards. https://en.wikipedia.org/wiki/Conformity https://www.wikidata.org/wiki/Q221284 social conformity social conformities conformity http://purl.bioontology.org/ontology/MESH/D012925 A personality trait rendering the individual acceptable in social or interpersonal relations. It is related to social acceptance, social approval, popularity, social status, leadership qualities, or any quality making him a socially desirable companion. social desirability http://id.loc.gov/authorities/subjects/sh85123936 http://purl.bioontology.org/ontology/MESH/D012928 Social and economic factors that characterize the individual or group within the social structure. socioeconomic factor socioeconomic factors http://purl.obolibrary.org/obo/NCIT_C17468 http://purl.bioontology.org/ontology/MESH/D012959 A state in the mid-atlantic United States. Its capital is Columbia. State bounded on the north by North Carolina, on the east and south by the Atlantic Ocean, and on the west by Georgia. State of South Carolina South Carolina South Carolinian http://purl.obolibrary.org/obo/NCIT_C43475 http://purl.bioontology.org/ontology/MESH/D013022 http://purl.bioontology.org/ontology/SNOMEDCT/421441001 South Carolinian South Carolinians Cytochrome P-450 monooxygenases (mixed function oxygenases) that are important in steroid biosynthesis and metabolism. https://en.wikipedia.org/wiki/Steroid_hydroxylase https://www.wikidata.org/wiki/Q16919122 steroid monooxygenase steroid hydroxylase steroid hydroxylases http://purl.bioontology.org/ontology/MESH/D013250 steroid monooxygenase steroid monooxygenases A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-ferrihemoprotein reductase. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Changes in the CYP17 gene cause congenital adrenal hyperplasia and differences of sexual differentiation. https://en.wikipedia.org/wiki/CYP17A1 https://www.wikidata.org/wiki/Q408305 steroid 17-alpha-hydroxylase steroid 17-alpha-hydroxylase/17,20 lyase steroid 17-alpha-monooxygenase steroid 17-alpha-monooxygenase. steroid 17α-monooxygenase steroid 17α-hydroxylase http://purl.obolibrary.org/obo/NCIT_C40068 17-hydroxylase 17α-hydroxylase http://purl.bioontology.org/ontology/MESH/D013254 http://purl.bioontology.org/ontology/SNOMEDCT/74032003 http://enzyme.expasy.org/EC/1.14.14.19 http://enzyme.expasy.org/EC/1.14.14.32 The formation of a fetus while another fetus is already present in the uterus. https://en.wikipedia.org/wiki/Superfetation https://www.wikidata.org/wiki/Q581100 superfoetation superfetation E1.0.0.0.0.0.19 http://purl.bioontology.org/ontology/MESH/D013476 http://purl.bioontology.org/ontology/SNOMEDCT/91271004 An intersex condition in persons with 46,XY karyotype, characterized by an abnormality of the genes encoding androgen receptors. An intersex condition that results in the partial or complete inability of the cell to respond to androgens. male pseudohermaphroditism due to androgen insensitivity https://en.wikipedia.org/wiki/Androgen_insensitivity_syndrome https://www.wikidata.org/wiki/Q512313 androgen-insensitivity syndrome androgen insensitivity syndrome, unspecified androgen resistance syndrome androgen insensitivity syndrome http://homosaurus.org/v2/androgenInsensitivitySyndrome 259.5 259.51 http://purl.obolibrary.org/obo/NCIT_C27226 AIS http://purl.bioontology.org/ontology/MEDDRA/10056292 E34.5 http://purl.bioontology.org/ontology/MESH/D013734 http://purl.bioontology.org/ontology/SNOMEDCT/12313004 http://purl.obolibrary.org/obo/DOID_4674 androgen insensitivity syndrome, unspecified E34.50 http://homosaurus.org/v2/androgenInsensitivitySyndrome An enzyme that catalyzes the reduction of testosterone to 5α-dihydrotestosterone. An oxidoreductase that catalyzes the conversion of 3-oxo-Δ4 steroids into their corresponding 5α form. It plays an important role in the conversion of testosterone into dihydrotestosterone and progesterone into dihydroprogesterone. https://en.wikipedia.org/wiki/5%CE%B1-Reductase https://www.wikidata.org/wiki/Q143333 3-oxo-5-alpha-steroid 4-dehydrogenase 3-oxo-5α-steroid 4-dehydrogenase 5-alpha reductase 5-alpha-reductase cholestenone 5-alpha-reductase 5α-reductase 5α-reductases http://purl.obolibrary.org/obo/NCIT_C17190 http://purl.bioontology.org/ontology/MESH/D013741 http://purl.bioontology.org/ontology/MESH/D042944 https://enzyme.expasy.org/EC/1.3.1.22 https://enzyme.expasy.org/EC/1.3.99.5 3-oxo-5-alpha-steroid 4-dehydrogenase 3-oxo-5-alpha-steroid 4-dehydrogenases 3-oxo-5α-steroid 4-dehydrogenase 3-oxo-5α-steroid 4-dehydrogenases 5-alpha reductase 5-alpha reductases 5-alpha-reductase 5-alpha-reductases Mental activity that is not predominantly perceptual by which one apprehends some aspect of an object or situation based on past learning and experience. thought thinking http://purl.obolibrary.org/obo/NCIT_C54226 http://purl.bioontology.org/ontology/MESH/D013850 http://purl.bioontology.org/ontology/SNOMEDCT/88952004 thought thoughts The process by which a tissue or aggregate of cells is kept alive outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism). tissue preservation http://purl.bioontology.org/ontology/MESH/D014021 A gonadal dysgenesis syndrome characterized by the absence of a part or all of one of the sex chromosomes. Signs and symptoms include short stature, webbing of neck, low-set ears, hypogonadism, and sterility. https://en.wikipedia.org/wiki/Turner_syndrome Turner syndrome due to structural X chromosome anomalies Turner syndrome, unspecified other variants of Turner syndrome Bonnevie-Ullrich syndrome Turner's syndrome Turner-Ullrich syndrome Ullrich-Turner syndrome Turner syndrome http://homosaurus.org/v2/turnerSyndrome http://id.loc.gov/authorities/subjects/sh85138930 RJ520.T87 758.6 http://purl.obolibrary.org/obo/NCIT_C26900 TS http://purl.bioontology.org/ontology/MEDDRA/10045181 Q96 http://purl.bioontology.org/ontology/MESH/D014424 http://purl.bioontology.org/ontology/SNOMEDCT/38804009 http://purl.obolibrary.org/obo/DOID_3491 Turner syndrome, unspecified Turner's syndrome, unspecified Q96.9 other variants of Turner syndrome other variants of Turner's syndrome Q96.8 http://homosaurus.org/v2/turnerSyndrome A country in North America, between Canada and Mexico, bordering both the North Atlantic Ocean and the North Pacific Ocean. https://en.wikipedia.org/wiki/United_States https://www.wikidata.org/wiki/Q30 United States of America United States American http://purl.obolibrary.org/obo/NCIT_C17234 US http://purl.bioontology.org/ontology/MESH/D014481 http://purl.bioontology.org/ontology/SNOMEDCT/223688001 United States of America U.S.A. USA American Note that "American" can also denote a person from the Americas (North or South America). Americans US U.S. A country located from the Baltic and Black seas to the Pacific Ocean and, for a time including 15 Soviet Socialist Republics. The capital was Moscow. https://en.wikipedia.org/wiki/Soviet_Union Soviet Union Union of Soviet Socialist Republics USSR 1922 1991 Soviet http://purl.bioontology.org/ontology/MESH/D014586 Soviet Soviets Bleeding from blood vessels in the uterus, sometimes manifested as vaginal bleeding. menstruation and uterine bleeding NEC uterine hemorrhage http://id.loc.gov/authorities/subjects/sh85060226 RG580.H5 RG711 RG821 http://purl.bioontology.org/ontology/MESH/D014592 menstruation and uterine bleeding NEC http://purl.bioontology.org/ontology/MEDDRA/10027335 Includes both producing and responding to words, either written or spoken. oral communication verbal communication verbal behavior verbal behaviors http://id.loc.gov/authorities/subjects/sh85095226 VB http://purl.bioontology.org/ontology/MESH/D014705 Created as the Kingdom of Serbs, Croats, and Slovenes in 1918. Yugoslavia became the official name in 1929. Bosnia-Herzegovina; Croatia; and Slovenia formed independent countries 7 April 1992. Macedonia became independent 8 February 1994 as the Former Yugoslav Republic of Macedonia (Macedonia Republic). https://en.wikipedia.org/wiki/Category:Yugoslavia https://en.wikipedia.org/wiki/Yugoslavia https://www.wikidata.org/wiki/Q36704 Yugoslavia 1918 1992 949.7 Yugoslav Yugoslavian http://purl.bioontology.org/ontology/MESH/D015022 949.7 20 Yugoslav Yugoslavs Yugoslavian Yugoslavians An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. https://en.wikipedia.org/wiki/3,4-Methylenedioxyamphetamine https://www.wikidata.org/wiki/Q223020 tenamfetamine 3,4-methylenedioxyamphetamine http://purl.obolibrary.org/obo/NCIT_C80152 MDA http://purl.bioontology.org/ontology/MESH/D015104 http://purl.bioontology.org/ontology/SNOMEDCT/44555003 The area in the United States comprised of the following states: Tennessee, Georgia, Florida, Alabama and Mississippi. The geographic area of the southeastern region of the United States in general or when the specific state or states are not included. The states usually included in this region are Alabama, Arkansas, Florida, Georgia, Louisiana, Mississippi, North Carolina, South Carolina, West Virginia, and Virginia. Southeastern United States http://purl.obolibrary.org/obo/NCIT_C43448 http://purl.bioontology.org/ontology/MESH/D015144 The geographic area of the midwestern region of the United States in general or when the specific state or states are not indicated. The states usually included in this region are Illinois, Indiana, Iowa, Kansas, Kentucky, Michigan, Minnesota, Missouri, Nebraska, Ohio, Oklahoma, North Dakota, South Dakota and Wisconsin. Midwestern United States http://purl.bioontology.org/ontology/MESH/D015146 The geographic area of the northwestern region of the United States. The states usually included in this region are Idaho, Montana, Oregon, Washington, and Wyoming. Northwestern United States http://purl.bioontology.org/ontology/MESH/D015205 The geographic area of the southwestern region of the United States. The states usually included in this region are Arizona, California, Colorado, Nevada, New Mexico, Texas, and Utah. Southwestern United States http://purl.bioontology.org/ontology/MESH/D015206 Preservation of cells, tissues, organs, or embryos by storage at low temperatures. https://en.wikipedia.org/wiki/Category:Cryopreservation https://en.wikipedia.org/wiki/Cryopreservation https://www.wikidata.org/wiki/Q1144664 cryopreservation of organs, tissues, etc. cryopreservation http://id.loc.gov/authorities/subjects/sh85034422 http://purl.obolibrary.org/obo/NCIT_C16475 http://purl.bioontology.org/ontology/MESH/D015925 A work consisting of a list of books, articles, documents, publications, and other items, usually on a single subject or related subjects. https://en.wikipedia.org/wiki/Bibliography https://en.wikipedia.org/wiki/Category:Bibliographies https://en.wikipedia.org/wiki/Category:Bibliography https://www.wikidata.org/wiki/Q134995 bibliography bibliographies 10 11 10 20 10 23 11 20 11 23 Work consisting of a statement of the opinions, beliefs, and policy of the editor or publisher of a journal, usually on current matters of medical or scientific significance to the medical community or society at large. The editorials published by editors of journals representing the official organ of a society or organization are generally substantive. editorial editorials Work consisting of written or printed communication between individuals or between persons and representatives of corporate bodies. The correspondence may be personal or professional. In medical and other scientific publications the letter is usually from one or more authors to the editor of the journal or book publishing the item being commented upon or discussed. https://en.wikipedia.org/wiki/Category:Letters_(message) https://en.wikipedia.org/wiki/Letter_(message) https://www.wikidata.org/wiki/Q133492 letter letters A reference book containing a list of words - usually in alphabetical order - giving information about form, pronunciation, etymology, grammar, and meaning. A foreign-language dictionary is an alphabetical list of words of one language with their meaning and equivalents in another language. dictionary dictionaries 413 http://purl.bioontology.org/ontology/MESH/D016437 413 23 Work consisting of a more or less comprehensive review of the literature on a specific subject, with usually an extensive critical analysis and synthesis of the literature. literature review review reviews http://purl.bioontology.org/ontology/MESH/D016454 literature review reviews of the literature review of the literature literature reviews A culture-specific acute delusional syndrome occurring mostly in the Malay people and Southern Chinese. The syndrome is characterized by the individual's sudden experience of depersonalization depicted by the belief that his penis is shrinking into his abdomen and that he will die when this occurs. Although generally classified as a culture-specific syndrome, koro may be no more than a variant of castration anxiety as it has been described in non-Asian patients. https://en.wikipedia.org/wiki/Koro_(medicine) https://www.wikidata.org/wiki/Q1080699 koro History obtained by gathering, preserving and interpreting the voices and memories of people, communities, and participants in past events. https://en.wikipedia.org/wiki/Category:Interviews https://en.wikipedia.org/wiki/Interview https://www.wikidata.org/wiki/Q178651 interview interviews Countries known in remote history (as Byzantium) or former names of countries reflecting political changes in the 19th or 20th century (as Germany, East). historical geographical location historical geographic location historical geographic locations http://purl.bioontology.org/ontology/MESH/D017516 historical geographical location historical geographical locations The period before menopause. In premenopausal women, the climacteric transition from full sexual maturity to cessation of ovarian cycle takes place between the age of late thirty and early fifty. pre-menopause pre-menopausal period premenopausal period premenopause http://purl.bioontology.org/ontology/MEDDRA/10051775 http://purl.bioontology.org/ontology/MESH/D017697 The physiological period following the menopause, the permanent cessation of the menstrual life. post menopause post-menopause post menopausal period post-menopausal period postmenopause http://purl.bioontology.org/ontology/MESH/D017698 Pain in the pelvic region of genital and non-genital origin. pelvic pain, NOS pelvic pain pelvic pains http://purl.obolibrary.org/obo/NCIT_C40122 http://purl.bioontology.org/ontology/MEDDRA/10034263 http://purl.bioontology.org/ontology/MESH/D017699 Geographical sites known to be extant in a remote period in the history of civilization, familiar as the names of ancient countries and empires. ancient world ancient land ancient lands http://purl.bioontology.org/ontology/MESH/D018436 ancient world Ancient World The endogenous peptides with opiate-like activity. The three major classes currently recognized are the enkephalins, the dynorphins, and the endorphins. Each of these families derives from different precursors, proenkephalin, prodynorphin, and pro-opiomelanocortin, respectively. There are also at least three classes of opioid receptors, but the peptide families do not map to the receptors in a simple way. https://en.wikipedia.org/wiki/Category:Opioid_peptides https://en.wikipedia.org/wiki/Opioid_peptide https://www.wikidata.org/wiki/Q417189 opioid peptide opioid peptides http://purl.bioontology.org/ontology/MESH/D018847 Works consisting of an account of the events, works, and achievements, personal and professional, during a person's life. https://en.wikipedia.org/wiki/Biography https://www.wikidata.org/wiki/Q36279 biography biographies 920 http://purl.bioontology.org/ontology/MESH/D019215 920 20 Work consisting of formal presentations made usually to fulfill requirements for an academic degree. https://en.wikipedia.org/wiki/Thesis thesis document academic dissertation academic dissertations Work consisting of publicly distributed notices, usually as paid announcements in mass media such as newspapers, magazines, or on billboards. They include those in motion picture, television advertising, radio, or electronic media. advertisement advertisements ad advert http://purl.bioontology.org/ontology/MESH/D019480 ad ads advert adverts A type of illustration, sometimes animated, typically in a non-realistic or semi-realistic style. The specific meaning has evolved over time, but the modern usage usually refers to either: an image or series of images intended for satire, caricature, or humor; or a motion picture that relies on a sequence of illustrations for its animation. https://en.wikipedia.org/wiki/Cartoon https://www.wikidata.org/wiki/Q627603 cartoon cartoons http://purl.bioontology.org/ontology/MESH/D019493 Work consisting of bibliographic records, created according to specific and uniform principles of construction and under the control of an authority file, which describe the materials contained in a collection, library, or group of libraries. Catalogs include also lists of materials prepared for a particular purpose, such as exhibition catalogs, sales catalogs, garden catalogs, medical supply catalogs. catalog catalogs Work consisting of records, usually private, of writers' experiences, observations, feelings, attitudes, etc. They may also be works marked in calendar order in which to note appointments and the like. diary diaries http://purl.bioontology.org/ontology/MESH/D019497 Work containing informational articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. https://en.wikipedia.org/wiki/Encyclopedia encyclopedia encyclopedias http://purl.bioontology.org/ontology/MESH/D019500 Works consisting of transient everyday items, usually printed on paper, that are produced for a specific limited use and then often thrown away. ephemera The area in the United States comprised of the following states: Alaska, Washington, Oregon, California and Hawaii. The geographic designation for states bordering on or located in the Pacific Ocean. The states so designated are Alaska, California, Hawaii, Oregon, and Washington. Pacific Coast States Pacific States http://purl.obolibrary.org/obo/NCIT_C43455 http://purl.bioontology.org/ontology/MESH/D019601 Work consisting of a structured file of information or a set of logically related data stored and retrieved using computer-based means. https://en.wikipedia.org/wiki/Category:Databases https://en.wikipedia.org/wiki/Database https://www.wikidata.org/wiki/Q8513 data base database databases http://id.loc.gov/authorities/subjects/sh86007767 QA76.9.D32 ZA4450-ZA4460 http://purl.obolibrary.org/obo/NCIT_C15426 DB http://purl.bioontology.org/ontology/MESH/D019991 data base data bases Synthetic organosiloxane gels that are formed from synthetic polymers of silicone oxide with organic sidechains (polydimethylsiloxane) by lengthening the polymer chains. Unlike silicone elastomers, they are not treated with amorphous silica. They are used as fillers in breast implants. silicone gel silicone gels sil http://purl.bioontology.org/ontology/MESH/D020034 Works consisting of brief accounts or narratives of incidents or events. https://en.wikipedia.org/wiki/Almanac https://en.wikipedia.org/wiki/Category:Almanacs https://www.wikidata.org/wiki/Q171341 almanac almanacs 30 30 20 Work consisting of collections of illustrative plates, charts, etc., usually with explanatory captions. https://en.wikipedia.org/wiki/Atlas https://en.wikipedia.org/wiki/Category:Atlases https://www.wikidata.org/wiki/Q162827 atlas atlases 912 912 20 Works consisting of self-described accounts. https://en.wikipedia.org/wiki/Autobiography https://en.wikipedia.org/wiki/Category:Autobiographies https://www.wikidata.org/wiki/Q4184 autobiography autobiographies 920 920 20 Work consisting exclusively or mainly of pictures but not technical drawings. pictorial work pictorial works http://purl.bioontology.org/ontology/MESH/D020495 Work listing and describing various sources of information, from multiple media or in different formats, on a given subject. resource guide resource guides The weight of the fetus in utero. It is usually estimated by various formulas based on measurements made during prenatal ultrasonography. fetal body weight fetal weight fetal weights http://purl.bioontology.org/ontology/MESH/D020567 fetal body weight fetal body weights A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population. http://semanticscience.org/resource/SIO_001329 https://en.wikipedia.org/wiki/Category:Single-nucleotide_polymorphisms https://en.wikipedia.org/wiki/Single-nucleotide_polymorphism https://www.wikidata.org/wiki/Q501128 single nucleotide polymorphism single-nucleotide polymorphism single-nucleotide polymorphisms http://id.loc.gov/authorities/subjects/sh2013002602 QH447.63.S56 http://purl.obolibrary.org/obo/NCIT_C18279 SNP http://purl.bioontology.org/ontology/MESH/D020641 single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs The expected function of a member of a particular profession. professional role professional roles Clinical and laboratory techniques used to enhance fertility in humans and animals. artificial fertilization assisted fertilization assisted reproductive technology assisted reproductive technique assisted reproductive techniques ART http://purl.bioontology.org/ontology/MESH/D027724 assisted fertilization http://purl.bioontology.org/ontology/MEDDRA/10003539 http://purl.bioontology.org/ontology/MEDDRA/10003540 http://purl.bioontology.org/ontology/SNOMEDCT/63487001 assisted reproductive technology https://en.wikipedia.org/wiki/Assisted_reproductive_technology https://en.wikipedia.org/wiki/Category:Assisted_reproductive_technology https://www.wikidata.org/wiki/Q25862 assisted reproductive technologies http://purl.obolibrary.org/obo/NCIT_C93282 http://purl.bioontology.org/ontology/MEDDRA/10080951 ART ARTs Organized services to provide diagnosis, treatment, and prevention of genetic disorders. genetic service genetic services http://purl.bioontology.org/ontology/MESH/D033142 A mammalian fetus expelled by induced abortion or spontaneous abortion. abortus aborted fetus aborted fetuses http://purl.obolibrary.org/obo/NCIT_C73436 http://purl.bioontology.org/ontology/MESH/D037881 A subclass of enzymes which includes all dehydrogenases acting on carbon-carbon bonds. This enzyme group includes all the enzymes that introduce double bonds into substrates by direct dehydrogenation of carbon-carbon single bonds. oxidoreductase which acts on CH-CH group donors oxidoreductases acting on CH-CH group donors oxidoreductases which acts on CH-CH group donors http://purl.bioontology.org/ontology/MESH/D044925 The period in the menstrual cycle that is optimal for fertilization of the ovum and yielding pregnancy. The duration of fertile period depends on the life span of male gametes within the female reproductive tract and the time of ovulation. It usually begins a few days before ovulation and ends on the day of ovulation. fertile period http://purl.bioontology.org/ontology/MESH/D046910 The transitional period before and after menopause. Perimenopausal symptoms are associated with irregular menstrual cycle and widely fluctuated hormone levels. They may appear 6 years before menopause and subside 2 to 5 years after menopause. peri-menopause perimenopause http://purl.bioontology.org/ontology/MESH/D047648 An endocrine state in men, characterized by a significant decline in the production of testosterone; dehydroepiandrosterone; and other hormones such as human growth hormone. Andropause symptoms are related to the lack of androgens including depression, sexual dysfunction, and osteoporosis. Andropause may also result from hormonal ablation therapy for malignant diseases. male climacterium andropause http://purl.bioontology.org/ontology/MEDDRA/10062756 http://purl.bioontology.org/ontology/MESH/D047649 male climacterium http://purl.bioontology.org/ontology/MEDDRA/10063112 Processes required for cell enlargement and cell proliferation. cell growth process cell growth processes http://purl.bioontology.org/ontology/MESH/D048708 A stage of development at which the adrenal glands undergo maturation leading to the capability of producing increasing amounts of adrenal androgens, dehydroepiandrosterone and androstenedione. Adrenarche usually begins at about 7 or 8 years of age before the signs of puberty and continues throughout puberty. https://en.wikipedia.org/wiki/Adrenarche https://www.wikidata.org/wiki/Q3774177 adrenarcheal adrenarche http://purl.bioontology.org/ontology/MESH/D050499 http://purl.bioontology.org/ontology/SNOMEDCT/103020000 Specific genre of publication. publication format publication formats The capability of producing yolk-filled eggs that hatch within the body, so that the young are born alive, but without placental attachment. This applies to certain species of reptiles and fishes. https://en.wikipedia.org/wiki/Ovoviviparity https://www.wikidata.org/wiki/Q192805 ovoviviparity ovoviviparous The capability of bearing live young (rather than eggs) in nonmammalian species. Some species of reptiles and fishes exhibit this. non-mammalian viviparity nonmammalian viviparity The capability of producing eggs (ova) from which young are hatched outside the body. While mostly referring to nonmammalian species, this does include mammals of the order Monotremata. https://en.wikipedia.org/wiki/Oviparity https://www.wikidata.org/wiki/Q212306 oviparity oviparous The concept covering the physical and mental health conditions experienced by members of minority groups, usually related to social disadvantages or discriminatory acts. minority health http://purl.obolibrary.org/obo/NCIT_C164016 http://purl.bioontology.org/ontology/MESH/D054525 Methods to detect and address an existing disease prior to the appearance of symptoms. Examples include treatment of hypertension (a risk factor for many cardiovascular diseases), cancer screenings. secondary prevention Methods to reduce the harm of symptomatic disease, such as disability or death, through rehabilitation and treatment. Examples include surgical procedures that halt the spread or progression of disease. tertiary prevention A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in sex-determining region Y protein. Many SOX transcription factors play important roles in regulating cell differentiation. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins. SOX transcription factor SOX transcription factors http://purl.bioontology.org/ontology/MESH/D055747 A German kingdom that constituted the state of Prussia between 1701 and 1918. It was the driving force behind the unification of Germany in 1871 and was the leading state of the German Empire until its dissolution in 1918. Although it took its name from the region called Prussia, it was based in the Margraviate of Brandenburg, where its capital was Berlin. Former state in north central Germany. Formally abolished March 1, 1947. Kingdom established 1701. https://en.wikipedia.org/wiki/Kingdom_of_Prussia https://en.wikipedia.org/wiki/Prussia Kingdom of Prussia Prussian Prussia http://purl.bioontology.org/ontology/MESH/D055787 Prussian Prussians The capability of individuals to recognize their own emotions and those of others, discern between different feelings and label them appropriately, use emotional information to guide thinking and behavior, and manage and/or adjust emotions to adapt to environments or achieve one's goal(s). https://en.wikipedia.org/wiki/Emotional_intelligence emotionally intelligent emotional intelligence EI A sultanate comprised at various times of parts of Europe, Asia, and Africa. Its period extends generally from 1301 to 1922. Ottoman Empire c. 1299 1922 Ottoman http://purl.bioontology.org/ontology/MESH/D057214 A dual monarchy formed in 1867. It included Austria; Hungary; Czechoslovakia; Moravia, Bukovina, Transylvania, Carniola, Kustenland, Dalmatia, Croatia; Fiume, and Galicia. https://en.wikipedia.org/wiki/Austria-Hungary Austro-Hungarian Empire Dual Monarchy Austria-Hungary 1867 1918 Austro-Hungarian http://purl.bioontology.org/ontology/MESH/D057235 Austro-Hungarian Austro-Hungarians The full set of chromosomes presented as a systematized array of metaphase chromosomes from a photomicrograph of a single cell nucleus arranged in pairs in descending order of size and according to the position of the centromere. https://en.wikipedia.org/wiki/Karyotype https://www.wikidata.org/wiki/Q189967 karyotype karyotypes http://id.loc.gov/authorities/subjects/sh85071686 http://purl.bioontology.org/ontology/MESH/D059785 http://purl.bioontology.org/ontology/SNOMEDCT/734840008 The state of the reproductive system when functioning optimally without evidence of disease, disorders, or deficiencies. https://en.wikipedia.org/wiki/Reproductive_health https://www.wikidata.org/wiki/Q1981388 reproductive health http://purl.bioontology.org/ontology/MESH/D060728 Individuals connecting by family, work or other interests. It also includes connectivity facilitated by computer-based communications. https://www.wikidata.org/wiki/Q19368491 social networking http://purl.obolibrary.org/obo/NCIT_C19035 Realm in central Europe consisting of a confederation of German and Italian territories under the suzerainty of an emperor and existing from the 9th or 10th century to 1806. https://en.wikipedia.org/wiki/Holy_Roman_Empire Holy Roman Empire 1806 Roman http://purl.bioontology.org/ontology/MESH/D060786 Roman Romans Anxiety related to the execution of a task. performance anxiety Online communities that allow for the creation and exchange of information and ideas. Platforms that provide the ability and tools to create and publish information accessed via the internet. Generally these platforms have three characteristics with content user generated, high degree of interaction between creator and viewer, and easily integrated with other sites. https://en.wikipedia.org/wiki/Social_media https://www.wikidata.org/wiki/Q202833 internet social media online social media social media http://homosaurus.org/v2/socialMedia http://homosaurus.org/v2/socialMedia Work consisting of accounts of individual experience in relation to a particular field or of participation in related activities. personal narrative personal narratives Group behavior toward others by virtue of their group membership which is prejudiced. prejudice and discrimination https://en.wikipedia.org/wiki/Discrimination discriminatory abuse discriminatory behavior social discrimination http://id.loc.gov/authorities/subjects/sh85038376 http://purl.obolibrary.org/obo/NCIT_C92450 discrimination http://purl.bioontology.org/ontology/MESH/D063508 prejudice and discrimination https://en.wikipedia.org/wiki/Category:Prejudice_and_discrimination discriminatory abuse https://en.wikipedia.org/wiki/Abuse#Discriminatory_abuse discriminatory behavior discriminatory behaviors An historical region of Western Asia situated within the Tigris–Euphrates river system, in the northern part of the Fertile Crescent, in modern days roughly corresponding to most of Iraq, Kuwait, the eastern parts of Syria, Southeastern Turkey, and regions along the Turkish–Syrian and Iran–Iraq borders. https://en.wikipedia.org/wiki/Category:Mesopotamia https://en.wikipedia.org/wiki/Mesopotamia https://www.wikidata.org/wiki/Q11767 ancient Mesopotamia Mesopotamia http://purl.bioontology.org/ontology/MESH/D064867 ancient Mesopotamia Ancient Mesopotamia An intense, urgent, or abnormal desire or longing (for food, drugs, alcohol, etc.). craving cravings Unicellular, prokaryotic organisms that reproduce by cell division and usually have cell walls; can be shaped like spheres, rods or spirals and can be found in virtually any environment. Eubacteria Neobacteria https://en.wikipedia.org/wiki/Bacteria https://en.wikipedia.org/wiki/Category:Bacteria https://species.wikimedia.org/wiki/Bacteria https://www.wikidata.org/wiki/Q10876 bacterium bacteria http://id.loc.gov/authorities/subjects/sh85010813 589.9 QR75-QR99.5 http://purl.obolibrary.org/obo/NCIT_C14187 http://purl.bioontology.org/ontology/MESH/D001419 http://purl.bioontology.org/ontology/SNOMEDCT/409822003 http://purl.obolibrary.org/obo/NCBITaxon_2 589.9 20 A living organism that has membranous cell walls, requires oxygen and organic foods, and is capable of voluntary movement, as distinguished from a plant or mineral. Euanimalia https://en.wikipedia.org/wiki/Animal https://en.wikipedia.org/wiki/Category:Animals https://species.wikimedia.org/wiki/Animalia https://www.wikidata.org/wiki/Q729 Animalia Metazoa metazoan animal animals http://id.loc.gov/authorities/subjects/sh85005249 590 591 QL http://purl.obolibrary.org/obo/NCIT_C14182 http://purl.bioontology.org/ontology/MESH/D000818 http://purl.bioontology.org/ontology/SNOMEDCT/387961004 http://purl.obolibrary.org/obo/NCBITaxon_33208 metazoan metazoans 590 23 591 20 A physical object is an identifiable collection of matter, which may be constrained by an identifiable boundary, and may move as a unit by translation or rotation, in 3-dimensional space. https://en.wikipedia.org/wiki/Physical_object https://www.wikidata.org/wiki/Q223557 physical object physical objects A physical object created by hand or machine. https://www.wikidata.org/wiki/Q22809652 manufactured good manufactured material manufactured product manufactured object manufactured objects http://purl.obolibrary.org/obo/NCIT_C97325 manufactured good https://en.wikipedia.org/wiki/Category:Manufactured_goods manufactured goods manufactured material manufactured materials http://purl.bioontology.org/ontology/MESH/D008420 http://purl.bioontology.org/ontology/SNOMEDCT/289926004 manufactured product http://purl.obolibrary.org/obo/ENVO_00003074 manufactured products Any number of entities (members) considered as a unit. https://www.wikidata.org/wiki/Q16887380 group groups http://purl.obolibrary.org/obo/NCIT_C43359 Any matter of defined composition that has discrete existence, whose origin may be biological, mineral or chemical. substance substances http://purl.obolibrary.org/obo/NCIT_C45306 http://purl.bioontology.org/ontology/SNOMEDCT/105590001 A group of materials of either plant, animal or artificial origin containing essential body nutrients that can be ingested by an organism to produce energy, stimulate growth, and maintain life. Any material that can be ingested by an organism. Substances taken in by the body to provide nourishment. https://en.wikipedia.org/wiki/Category:Foods https://en.wikipedia.org/wiki/Food https://www.wikidata.org/wiki/Q2095 food material foodstuff food foods http://id.loc.gov/authorities/subjects/sh85050184 GN407-GN411.5 RA601-RA602 TX341-TX641 http://purl.obolibrary.org/obo/NCIT_C62695 http://purl.bioontology.org/ontology/MESH/D005502 http://purl.obolibrary.org/obo/CHEBI_33290 food material food materials foodstuff foodstuffs http://purl.obolibrary.org/obo/CHEBI_33290 Note that "food" herein is defined as a physiological role by a substance. Single-celled organisms lacking nuclei, similar to prokaryotes in most aspects of cell structure and metabolism. However, their genetic transcription and translation do not show the typical bacterial features, but are extremely similar to those of eukaryotes. Archaebacteria https://en.wikipedia.org/wiki/Archaea https://en.wikipedia.org/wiki/Category:Archaea https://species.wikimedia.org/wiki/Archaea https://www.wikidata.org/wiki/Q10872 archaeon archaea http://id.loc.gov/authorities/subjects/sh86006229 QR82.A69 http://purl.obolibrary.org/obo/NCIT_C61092 http://purl.bioontology.org/ontology/MESH/D001105 http://purl.bioontology.org/ontology/SNOMEDCT/419036000 http://purl.obolibrary.org/obo/NCBITaxon_2157 Organism or cells with a nucleus separated from the cytoplasm by a two membrance nuclear envelope and compartmentalization of function into distinct cytoplasmic organelles. https://en.wikipedia.org/wiki/Category:Eukaryotes https://en.wikipedia.org/wiki/Eukaryote https://species.wikimedia.org/wiki/Eukaryota https://www.wikidata.org/wiki/Q19088 Caryonta Eucarya Eucaryota Eucaryotae Eucytota Eukarya Eukaryonta Eukaryota Eukaryotae Karyonta eukaryote eukaryotes http://purl.obolibrary.org/obo/NCIT_C25796 http://purl.bioontology.org/ontology/MESH/D056890 http://purl.obolibrary.org/obo/NCBITaxon_2759 An entity is anything that exists or has existed or will exist. https://www.wikidata.org/wiki/Q35120 entity entities entitātem A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. continuant continuants continuant continuānt An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies a temporal region or a spatiotemporal region. occurrent occurrents occurrent occurrēns b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. independent continuant independent continuants independent A region of time. temporal region temporal regions http://purl.org/sig/ont/fma/fma312872 A process is an entity that is identifiable only through the unfolding of time, has temporal parts, and unless otherwise specified/predicted, cannot be identified from any instant of time in which it exists. https://en.wikipedia.org/wiki/Process https://www.wikidata.org/wiki/Q3249551 process processes procès procés prōcessus A realizable entity is an attribute that is exhibited under some condition and is realized in some process. realisable entity realizable entity realizable entities realizable realisable entity realisable entities A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities. A quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. A quality is an attribute that is intrinsically associated with its bearer (or its parts), but whose presence/absence and observed/measured value may vary. https://en.wikipedia.org/wiki/Quality_(philosophy) https://www.wikidata.org/wiki/Q1207505 The etymology of "quality" is fairly well elucidated coming from Middle English, from Old French qualité, from Latin qualitatem, accusative of qualitas, from qualis (“of what kind”), from Proto-Indo-European *kʷo- (“who, how”). Cicero coined qualitas as a calque to translate the Ancient Greek word ποιότης (poiótēs, “quality”), coined by Plato from ποῖος (poîos, “of what nature, of what kind”). quality qualities qualitatem qualité b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. specifically dependent continuant specifically dependent continuants dependent specifically A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. A role is a realizable entity that describes behaviours, rights and obligations of an entity in some particular circumstance. role roles role roule A material entity that is part of an object but is not demarcated by any physical discontinuities. fiat object part fiat object parts http://purl.obolibrary.org/obo/BFO_0000024 A position in relation to its surroundings. A site is a spatial region bounded (in part or in whole) by material entities and may be occupied by material entities. site sites An object is an entity that is wholly identifiable at any instant of time during which it exists. object objects obiectum b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. generically dependent continuant generically dependent continuants dependent generically A material entity is a physical entity that is spatially extended, exists as a whole at any point in time and has mass. https://www.wikidata.org/wiki/Q53617407 material material entity material entities material materials http://purl.bioontology.org/ontology/SNOMEDCT/260769002 An entity which is immaterial. immaterial entity immaterial entities immaterial A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. http://purl.obolibrary.org/obo/HIV_5739 https://en.wikipedia.org/wiki/Zidovudine https://www.wikidata.org/wiki/Q198504 azidothymidine zidovudine http://id.loc.gov/authorities/subjects/sh89007049 http://purl.obolibrary.org/obo/NCIT_C947 ZDV J05AF01 http://purl.bioontology.org/ontology/SNOMEDCT/387151007 http://purl.obolibrary.org/obo/CHEBI_10110 azidothymidine AZT Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa. volatile organic compound volatile organic compounds VOC http://purl.obolibrary.org/obo/CHEBI_134179 VOC VOCs An estrogen medication which is used in hormonal birth control for cisgender women. It is formulated in combination with dihydroxyprogesterone acetophenide (DHPA; algestone acetophenide), a progestin, and is used specifically as a combined injectable contraceptive. Estradiol enantate is not available for medical use alone. The medication, in combination with DHPA, is given by injection into muscle once a month. https://en.wikipedia.org/wiki/Estradiol_enantate https://www.wikidata.org/wiki/Q5401763 estradiol enantate estradiol enanthate http://purl.obolibrary.org/obo/NCIT_C76996 E2-EN EEn http://purl.bioontology.org/ontology/MESH/C002027 http://purl.bioontology.org/ontology/SNOMEDCT/708186001 http://purl.obolibrary.org/obo/CHEBI_135604 An estrogen medication which has been used in the treatment of prostate cancer in cisgender men. It has also been used as a part of hormone therapy for transgender women. Although estradiol undecylate has been used in the past, it was discontinued and hence is no longer available. The medication has been given by injection into muscle usually once a month. https://en.wikipedia.org/wiki/Estradiol_undecylate https://www.wikidata.org/wiki/Q5401764 estradiol undecylate EU http://purl.obolibrary.org/obo/CHEBI_135719 Testosterone undecanoate, sold for use by mouth under the brand names Andriol and Jatenzo and for use by injection under the brand names Aveed and Nebido, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men, which includes hormone therapy for transgender men. It is taken by mouth two to three times per day with food or given by injection into muscle once every 3.5 days to 2 weeks, depending on individual response. The undecanoate ester form of the androgen testosterone, with gonadotropin-secretory inhibiting and hormone replacement activity. As testosterone inhibits the secretion of gonadotropins from the pituitary gland, administration of testosterone decreases the secretion of luteinizing hormone (LH). By inhibiting LH secretion, the growth of Leydig cells, which are normally stimulated by LH to produce testosterone, may be suppressed. https://en.wikipedia.org/wiki/Testosterone_undecanoate https://www.wikidata.org/wiki/Q15410178 testosterone undecanoate http://purl.obolibrary.org/obo/NCIT_C1249 http://purl.bioontology.org/ontology/MESH/C010792 http://purl.bioontology.org/ontology/SNOMEDCT/395900004 http://purl.obolibrary.org/obo/CHEBI_135741 A potent synthetic analog of gonadotropin-releasing hormone with D-serine substitution at residue 6, glycine10 deletion, and other modifications. A synthetic analog of gonadotropin-releasing hormone (GnRH). Buserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of buserelin results in sustained inhibition of gonadotropin production, suppression of testicular and ovarian steroidogenesis, and reduced levels of circulating gonadotropin and gonadal steroids. Buserelin is more potent that GnRH. https://en.wikipedia.org/wiki/Buserelin https://www.wikidata.org/wiki/Q414745 buserelin http://purl.obolibrary.org/obo/NCIT_C320 L02AE01 http://purl.bioontology.org/ontology/MESH/D002064 http://purl.bioontology.org/ontology/SNOMEDCT/395744006 http://purl.obolibrary.org/obo/CHEBI_135907 The acetate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol acetate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. https://en.wikipedia.org/wiki/Estradiol_acetate https://www.wikidata.org/wiki/Q5401757 estradiol acetate http://purl.obolibrary.org/obo/NCIT_C47990 EA http://purl.bioontology.org/ontology/SNOMEDCT/414140005 http://purl.obolibrary.org/obo/CHEBI_135981 A 3-oxo steroid that has alpha configuration at position 5. 3-oxo-5alpha-steroid 3-oxo-5α-steroid 3-oxo-5α-steroids http://purl.obolibrary.org/obo/CHEBI_13601 3-oxo-5alpha-steroid 3-oxo-5alpha-steroids A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5. An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. https://en.wikipedia.org/wiki/MDMA https://www.wikidata.org/wiki/Q69488 ecstasy molly MDMA N-Methyl-3,4-methylenedioxyamphetamine 3,4-methylenedioxymethamphetamine http://homosaurus.org/v2/MDMA http://id.loc.gov/authorities/subjects/sh89002646 HV5822.M38 RM666.M35 http://purl.obolibrary.org/obo/NCIT_C61081 http://purl.bioontology.org/ontology/MESH/D018817 http://purl.bioontology.org/ontology/SNOMEDCT/288459003 http://purl.obolibrary.org/obo/CHEBI_1391 ecstasy E http://homosaurus.org/v2/MDMA A metabolite of estriol with a 15-alpha-hydroxyl group. Estetrol can be converted from estriol sulfate or dehydroepiandrosterone sulfate by the fetal-placental unit. https://en.wikipedia.org/wiki/Estetrol https://en.wikipedia.org/wiki/Estetrol_(medication) estetrol http://purl.bioontology.org/ontology/MESH/D004953 http://purl.obolibrary.org/obo/CHEBI_142773 A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. primary alcohol primary alcohols http://purl.obolibrary.org/obo/CHEBI_15734 A peptide containing ten or more amino acid residues. polypeptide polypeptides http://purl.obolibrary.org/obo/CHEBI_15841 A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group. https://en.wikipedia.org/wiki/Category:Ethanol https://en.wikipedia.org/wiki/Ethanol https://www.wikidata.org/wiki/Q153 ethyl alcohol ethanol http://id.loc.gov/authorities/subjects/sh2009007801 V03AB16 http://purl.bioontology.org/ontology/MEDDRA/10015527 http://purl.bioontology.org/ontology/MESH/D000431 http://purl.bioontology.org/ontology/SNOMEDCT/419442005 http://purl.obolibrary.org/obo/CHEBI_16236 A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5. A potent androgenic metabolite of testosterone. It is produced by the action of the enzyme 3-oxo-5-alpha-steroid 4-dehydrogenase. The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and adrenal glands by 5-alpha reductase. Dihydrotestosterone exerts its action similar to testosterone, which binds to and activates specific nuclear androgen receptors. After translocation into the nucleus, the activated hormone-receptor complex binds to the androgen response elements on the DNA and activates gene expressions that are required for sex development. Dihydrotestosterone is responsible for the formation of male primary sex characteristics and most male secondary sex characteristics during puberty, such as muscular growth, facial and body hair growth, and deepening of the voice. https://en.wikipedia.org/wiki/Dihydrotestosterone https://www.wikidata.org/wiki/Q411054 17beta-hydroxy-5alpha-androstan-3-one androstanolone dihydrotestosterone https://en.wikipedia.org/wiki/Androstanolone https://www.wikidata.org/wiki/Q31686490 stanolone 17β-hydroxy-5α-androstan-3-one http://purl.obolibrary.org/obo/NCIT_C29619 http://purl.bioontology.org/ontology/MESH/D013196 http://purl.bioontology.org/ontology/SNOMEDCT/103042004 http://purl.obolibrary.org/obo/CHEBI_16330 dihydrotestosterone DHT A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol. A steroid hormone synthesized by the adrenal glands and the gonads from either 17-alpha-hydroxyprogesterone or dehydroepiandrosterone and is a precursor of testosterone. https://en.wikipedia.org/wiki/Androstenedione androstenedione androst-4-ene-3,17-dione http://id.loc.gov/authorities/subjects/sh99001784 QP572.A52 http://purl.obolibrary.org/obo/NCIT_C2300 http://purl.bioontology.org/ontology/MESH/D000735 http://purl.bioontology.org/ontology/SNOMEDCT/56146000 http://purl.obolibrary.org/obo/CHEBI_16422 Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc. Members of the class of compounds composed of amino acids joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. oligopeptides are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. proteins are linear polypeptides that are normally synthesized on ribosomes. https://en.wikipedia.org/wiki/Category:Peptides https://en.wikipedia.org/wiki/Peptide https://www.wikidata.org/wiki/Q172847 peptide peptides http://id.loc.gov/authorities/subjects/sh85099692 QD431-QD431.7 QP552.P4 http://purl.bioontology.org/ontology/MESH/D010455 http://purl.obolibrary.org/obo/CHEBI_16670 A 16-hydroxy steroid in which the hydroxy group at position 16 has alpha-configuration. 16alpha-hydroxy steroid 16α-hydroxy steroid 16α-hydroxy steroids http://purl.obolibrary.org/obo/CHEBI_16799 16alpha-hydroxy steroid 16alpha-hydroxy steroids Produced in the corpus luteum and by the placenta, as an antagonist of estrogens. Promotes proliferation of uterine mucosa and the implantation of the blastocyst, prevents further follicular development. The major progestational steroid that is secreted primarily by the corpus luteum and the placenta. Progesterone acts on the uterus, the mammary glands and the brain. It is required in embryo implantation; pregnancy maintenance, and the development of mammary tissue for milk production. Progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids. https://en.wikipedia.org/wiki/Category:Progesterone https://en.wikipedia.org/wiki/Progesterone https://en.wikipedia.org/wiki/Progesterone_(medication) progesterone http://purl.obolibrary.org/obo/NCIT_C2297 http://purl.bioontology.org/ontology/MEDDRA/10063291 http://purl.bioontology.org/ontology/MESH/D011374 http://purl.bioontology.org/ontology/SNOMEDCT/16683002 http://purl.obolibrary.org/obo/CHEBI_17026 A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H). Organic compounds with a carbonyl group (C=O) bonded to two other carbon atoms as the skeleton structure. Acetone is the simplest ketone compound. https://en.wikipedia.org/wiki/Category:Ketones https://en.wikipedia.org/wiki/Ketone ketone ketones http://purl.obolibrary.org/obo/NCIT_C94716 http://purl.bioontology.org/ontology/SNOMEDCT/59431004 http://purl.obolibrary.org/obo/CHEBI_17087 Any 3beta-hydroxy-steroid that contains a double bond between positions 5 and 6. 3beta-hydroxy-Delta(5)-steroid 3β-hydroxy-Δ5-steroid 3β-hydroxy-Δ5-steroids http://purl.obolibrary.org/obo/CHEBI_1722 3beta-hydroxy-Delta(5)-steroid 3beta-hydroxy-Delta(5)-steroids A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17. One of three naturally occurring estrogens synthesized from androstenedione in the adrenal glands and peripheral tissues by aromatization and is the primary estrogen produced after menopause. https://en.wikipedia.org/wiki/Estrone https://en.wikipedia.org/wiki/Estrone_(medication) https://www.wikidata.org/wiki/Q414986 https://www.wikidata.org/wiki/Q55611080 E1 oestrone estrone http://id.loc.gov/authorities/subjects/sh85045016 http://purl.obolibrary.org/obo/NCIT_C2294 G03CA07 http://purl.bioontology.org/ontology/MEDDRA/10063281 http://purl.bioontology.org/ontology/MESH/D004970 http://purl.bioontology.org/ontology/SNOMEDCT/51775003 http://purl.obolibrary.org/obo/CHEBI_17263 A potent androgenic steroid and major product secreted by the Leydig cells of the testis. Its production is stimulated by luteinizing hormone from the pituitary gland. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to dihydrotestosterone or estradiol. An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.. testosterone http://homosaurus.org/v2/testosterone http://id.loc.gov/authorities/subjects/sh85134159 QP572.T4 http://purl.obolibrary.org/obo/NCIT_C2299 T http://purl.bioontology.org/ontology/MEDDRA/10043364 http://purl.bioontology.org/ontology/MESH/D013739 http://purl.bioontology.org/ontology/SNOMEDCT/81118006 http://purl.obolibrary.org/obo/CHEBI_17347 http://homosaurus.org/v2/testosterone T "Lipids" is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. https://en.wikipedia.org/wiki/Category:Lipids https://en.wikipedia.org/wiki/Lipid https://www.wikidata.org/wiki/Q11367 lipid lipids http://purl.org/sig/ont/fma/fma67264 http://purl.obolibrary.org/obo/NCIT_C616 http://purl.bioontology.org/ontology/SNOMEDCT/70106000 http://purl.obolibrary.org/obo/CHEBI_18059 A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it. nitrile nitriles http://purl.obolibrary.org/obo/CHEBI_18379 Any oxo steroid carrying the oxo group at position 17. https://www.wikidata.org/wiki/Q929864 17 ketosteroid 17 oxosteroid 17-ketosteroid 17-oxosteroid 17-oxo steroid 17-oxo steroids http://purl.bioontology.org/ontology/MESH/D015068 http://purl.bioontology.org/ontology/SNOMEDCT/46120009 http://purl.obolibrary.org/obo/CHEBI_19168 17 ketosteroid 17 ketosteroids 17 oxosteroid 17 oxosteroids 17-ketosteroid 17-ketosteroids 17-oxosteroid 17-oxosteroids A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond. N-glycosyl compound N-glycosyl compounds http://purl.obolibrary.org/obo/CHEBI_21731 Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. https://en.wikipedia.org/wiki/Alkaloid https://en.wikipedia.org/wiki/Category:Alkaloids https://www.wikidata.org/wiki/Q70702 alkaloid alkaloids http://id.loc.gov/authorities/subjects/sh85003598 QD421-QD421.7 QK898.A4 RM666.A4 RS431.A53 http://purl.obolibrary.org/obo/CHEBI_22315 Any purine having at least one amino substituent. aminopurine aminopurines http://purl.obolibrary.org/obo/CHEBI_22527 A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system. arenecarboxamide arenecarboxamides http://purl.obolibrary.org/obo/CHEBI_22645 Any nitrogen molecular entity containing the group -N3. https://en.wikipedia.org/wiki/Azide https://en.wikipedia.org/wiki/Category:Azides https://www.wikidata.org/wiki/Q407627 azide azides http://purl.obolibrary.org/obo/CHEBI_22680 A class of drugs characterized as central nervous system (CNS) depressants. Barbiturate compounds bind to the gamma amino butyric acid (GABA)-A receptor, thereby increasing the influx of chloride ions into the neuron and subsequently causing hyperpolarization, which produces a decrease in neuronal transmission. Other barbiturate effects in the CNS may include modulation of sodium and calcium channels as well as inhibition of glutamate-mediated excitation. Although the effects of barbiturates are seen throughout the CNS, the predominant effect occurs in the midbrain region, the part of the brain associated with arousal. CNS depressive effects associated with this drug class include mild sedation, hypnosis, anesthesia, and coma as well as a decrease in seizure activity. Members of the class of pyrimidones consisting of pyrimidine-2,4,6(1H,3H,5H)-trione (barbituric acid) and its derivatives. Largest group of the synthetic sedative/hypnotics, sharing a characteristic six-membered ring structure. https://en.wikipedia.org/wiki/Barbiturate https://en.wikipedia.org/wiki/Category:Barbiturates https://www.wikidata.org/wiki/Q206348 barbiturate barbiturates http://id.loc.gov/authorities/subjects/sh85011804 RM325 http://purl.obolibrary.org/obo/NCIT_C67084 http://purl.bioontology.org/ontology/SNOMEDCT/372798009 http://purl.obolibrary.org/obo/CHEBI_22693 Any of various benzoic acid amides. benzamide benzamides http://purl.bioontology.org/ontology/MESH/D001549 http://purl.obolibrary.org/obo/CHEBI_22702 Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives. benzene benzenes http://purl.obolibrary.org/obo/CHEBI_22712 A halogen molecular entity containing one or more atoms of chlorine. chlorine molecular entity chlorine molecular entities http://purl.obolibrary.org/obo/CHEBI_23117 Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines. chlorobenzene chlorobenzenes http://purl.obolibrary.org/obo/CHEBI_23132 Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. molecular entity molecular entities http://purl.obolibrary.org/obo/CHEBI_23367 Salts and C-organyl derivatives of hydrogen cyanide, HC#N. cyanide cyanides http://purl.obolibrary.org/obo/CHEBI_23424 An amide which is cyclic. cyclic amide cyclic amides http://purl.obolibrary.org/obo/CHEBI_23443 Any alicyclic ketone based on a cyclohexane skeleton and its substituted derivatives thereof. cyclohexanone cyclohexanones http://purl.bioontology.org/ontology/SNOMEDCT/15764009 http://purl.obolibrary.org/obo/CHEBI_23482 The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. The most potent form of the naturally occurring steroid sex hormone in humans, produced by ovary, placenta, testis, and in small amount by adrenal cortex. Estradiol binds to a specific intracellular estrogen receptor located in female organs, breasts, hypothalamus and pituitary. The receptor-ligand complex promotes gene expression necessary for the maintenance of fertility and secondary sexual characteristics in females. In addition, estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Estradiol, the principal intracellular human estrogen, is substantially more active at the cellular level than its metabolites, estrone and estriol. https://en.wikipedia.org/wiki/Category:Estradiol https://en.wikipedia.org/wiki/Estradiol https://en.wikipedia.org/wiki/Estradiol_(medication) estradiol http://id.loc.gov/authorities/subjects/sh85045006 QP572.E8 http://purl.obolibrary.org/obo/NCIT_C2295 G03CA03 http://purl.bioontology.org/ontology/MEDDRA/10015499 http://purl.bioontology.org/ontology/MESH/D004958 http://purl.bioontology.org/ontology/SNOMEDCT/126172005 http://purl.obolibrary.org/obo/CHEBI_23965 Any primary alcohol based on an ethanol skeleton. ethanol ethanols http://purl.obolibrary.org/obo/CHEBI_23982 A halogen molecular entity containing one or more atoms of fluorine. fluorine molecular entity fluorine molecular entities http://purl.obolibrary.org/obo/CHEBI_24062 A corticosteroid that supports a variety of cardiovascular, metabolic, immunologic, and homeostatic functions, and which binds specifically to the glucocorticoid receptor (GR; NR3C1). Glucocorticoid binding to GR leads to the transportation of the activated receptor-glucocorticoid complex to the nucleus, after which it binds to glucocorticoid response elements (GRE) and regulates the expression of GR-responsive genes. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. https://en.wikipedia.org/wiki/Category:Glucocorticoids https://en.wikipedia.org/wiki/Glucocorticoid https://www.wikidata.org/wiki/Q422549 glucocorticosteroid glucocorticoid glucocorticoids http://purl.obolibrary.org/obo/NCIT_C2323 H02AB http://purl.bioontology.org/ontology/MESH/D005938 http://purl.bioontology.org/ontology/SNOMEDCT/419933005 http://purl.obolibrary.org/obo/CHEBI_24261 glucocorticosteroid glucocorticosteroids A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. https://www.wikidata.org/wiki/Q43460564 chemical entity chemical entities http://purl.obolibrary.org/obo/CHEBI_24431 Any p-block molecular entity containing a halogen. halogen molecular entity halogen molecular entities http://purl.obolibrary.org/obo/CHEBI_24471 A cyclic compound having as ring members atoms of carbon and at least of one other element. organic heterocyclic compound organic heterocyclic compounds http://purl.obolibrary.org/obo/CHEBI_24532 Any of a class of substances containing hydroxy groups. https://en.wikipedia.org/wiki/Category:Hydroxides hydroxide hydroxides http://purl.obolibrary.org/obo/CHEBI_24651 A salt is an assembly of cations and anions. salt salts http://purl.obolibrary.org/obo/CHEBI_24866 A salt that contains an organic ion. organic salt organic salts http://purl.obolibrary.org/obo/CHEBI_24868 Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. lactam lactams http://purl.obolibrary.org/obo/CHEBI_24995 Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are macrolides. https://en.wikipedia.org/wiki/Category:Lactones https://en.wikipedia.org/wiki/Lactone https://www.wikidata.org/wiki/Q59078 lactone lactones http://id.loc.gov/authorities/subjects/sh85073870 QD305.A2 http://purl.bioontology.org/ontology/MESH/D007783 http://purl.bioontology.org/ontology/SNOMEDCT/419190006 http://purl.obolibrary.org/obo/CHEBI_25000 Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol. methyl ester methyl esters http://purl.obolibrary.org/obo/CHEBI_25248 Any of a class of salts and esters of nitrous acid. https://www.wikidata.org/wiki/Q72157355 nitrite nitrites http://purl.bioontology.org/ontology/MESH/D009573 http://purl.obolibrary.org/obo/CHEBI_25549 A peptide containing a relatively small number of amino acids. https://en.wikipedia.org/wiki/Oligopeptide https://www.wikidata.org/wiki/Q2157266 oligopeptide oligopeptides http://purl.obolibrary.org/obo/CHEBI_25676 An organic compound with one ring structure. organic heteromonocyclic compound organic heteromonocyclic compounds http://purl.obolibrary.org/obo/CHEBI_25693 An organic compound in which two carbon atoms are linked through an oxygen atom (C-O-C). An ether may be a product of the condensation of alcohols. Ether also refers loosely to diethyl-ether, a colorless, volatile, highly inflammable liquid used in industry and biomedical research, and historically important as an anesthetic agent. In vivo, ether acts similarly to alcohol and chloroform, but its stimulant action on the heart is much more marked. Ether is a rapidly diffusible stimulant. An organooxygen compound with formula ROR, where R is not hydrogen. https://en.wikipedia.org/wiki/Category:Ethers https://en.wikipedia.org/wiki/Ether https://www.wikidata.org/wiki/Q103230 ether ethers http://id.loc.gov/authorities/subjects/sh85045088 QD305.E7 QD341.E7 http://purl.obolibrary.org/obo/NCIT_C29819 http://purl.bioontology.org/ontology/SNOMEDCT/3601005 http://purl.obolibrary.org/obo/CHEBI_25698 An alcohol derived from an aliphatic compound. aliphatic alcohol aliphatic alcohols http://purl.obolibrary.org/obo/CHEBI_2571 A molecular entity contaning oxygen. oxygen molecular entity oxygen molecular entities http://purl.obolibrary.org/obo/CHEBI_25806 Any of a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group. Compounds that are derived from piperazine. piperazine piperazines http://purl.bioontology.org/ontology/MESH/D010879 http://purl.obolibrary.org/obo/CHEBI_26144 Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group. https://en.wikipedia.org/wiki/Category:Polyphenols https://en.wikipedia.org/wiki/Polyphenol polyphenol polyphenols http://purl.obolibrary.org/obo/NCIT_C28203 http://purl.bioontology.org/ontology/SNOMEDCT/416908008 http://purl.obolibrary.org/obo/CHEBI_26195 A class of imidazopyrimidines that consists of purine and its substituted derivatives. https://en.wikipedia.org/wiki/Category:Purines purine purines http://purl.obolibrary.org/obo/CHEBI_26401 Any steroid that acts as hormone. Hormones possessing the steroid ring system; e.g., androgens, estrogens, adrenocortical hormones. https://en.wikipedia.org/wiki/Steroid_hormone steroid hormone steroid hormones http://id.loc.gov/authorities/subjects/sh85128053 QP572.S7 http://purl.org/sig/ont/fma/fma83353 http://purl.obolibrary.org/obo/NCIT_C2289 http://purl.bioontology.org/ontology/SNOMEDCT/112113009 http://purl.obolibrary.org/obo/CHEBI_26764 A molecular entity which is both a steroid and a lactone. steroid lactone steroid lactones http://purl.obolibrary.org/obo/CHEBI_26766 A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is dextroamphetamine. A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine. https://en.wikipedia.org/wiki/Amphetamine https://en.wikipedia.org/wiki/Category:Amphetamine https://www.wikidata.org/wiki/Q179452 alpha-methylphenethylamine amphetamine http://purl.obolibrary.org/obo/NCIT_C62006 http://purl.bioontology.org/ontology/MESH/D000661 http://purl.bioontology.org/ontology/SNOMEDCT/703842006 http://purl.obolibrary.org/obo/CHEBI_2679 A molecular entity contaning sulfur. sulfur molecular entity sulfur molecular entities http://purl.obolibrary.org/obo/CHEBI_26835 An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur. thiocarboxylic ester thiocarboxylic esters http://purl.obolibrary.org/obo/CHEBI_26959 An organic compound with two different ring structures. organic heterobicyclic compound organic heterobicyclic compounds http://purl.obolibrary.org/obo/CHEBI_27171 A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca. A tropane alkaloid with central nervous systems (CNS) stimulating and local anesthetic activity. Cocaine binds to the dopamine, serotonin, and norepinephrine transport proteins and inhibits the re-uptake of dopamine, serotonin, and norepinephrine into pre-synaptic neurons. This leads to an accumulation of the respective neurotransmitters in the synaptic cleft and may result in increased postsynaptic receptor activation. The mechanism of action through which cocaine exerts its local anesthetic effects is by binding to and blocking the voltage-gated sodium channels in the neuronal cell membrane. By stabilizing neuronal membranes, cocaine inhibits the initiation and conduction of nerve impulses and produces a reversible loss of sensation. An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake. https://en.wikipedia.org/wiki/Category:Cocaine https://en.wikipedia.org/wiki/Cocaine https://en.wikipedia.org/wiki/Cocaine_(data_page) https://www.wikidata.org/wiki/Q41576 coke cocaine http://homosaurus.org/v2/cocaine http://id.loc.gov/authorities/subjects/sh85027558 RD86.C6 http://purl.obolibrary.org/obo/NCIT_C80153 http://purl.bioontology.org/ontology/MESH/D003042 http://purl.bioontology.org/ontology/SNOMEDCT/387085005 http://purl.obolibrary.org/obo/CHEBI_27958 http://homosaurus.org/v2/cocaine A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer). A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, a large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. https://en.wikipedia.org/wiki/Estriol https://en.wikipedia.org/wiki/Estriol_(medication) https://www.wikidata.org/wiki/Q409721 https://www.wikidata.org/wiki/Q55611075 E3 oestriol estriol http://purl.obolibrary.org/obo/NCIT_C80154 http://purl.bioontology.org/ontology/MEDDRA/10030234 http://purl.bioontology.org/ontology/MESH/D004964 http://purl.bioontology.org/ontology/SNOMEDCT/73723004 http://purl.obolibrary.org/obo/CHEBI_27974 A phenethylamine alkaloid that is phenethylamine substituted at positions 3, 4 and 5 by methoxy groups. Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church. https://en.wikipedia.org/wiki/Mescaline https://www.wikidata.org/wiki/Q193140 3,4,5-trimethoxyphenethylamine mescaline http://id.loc.gov/authorities/subjects/sh85083910 BF209.M4 http://purl.bioontology.org/ontology/MESH/D008635 http://purl.bioontology.org/ontology/SNOMEDCT/373780001 http://purl.obolibrary.org/obo/CHEBI_28346 A major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands. https://en.wikipedia.org/wiki/Dehydroepiandrosterone https://www.wikidata.org/wiki/Q408376 3-beta-hydroxy-5-androsten-17-one 3-β-hydroxy-5-androsten-17-one 3β-Hydroxyandrost-5-en-17-one dehydroepiandrosterone http://id.loc.gov/authorities/subjects/sh90004019 http://purl.obolibrary.org/obo/NCIT_C2265 DHEA http://purl.bioontology.org/ontology/MESH/D003687 http://purl.bioontology.org/ontology/SNOMEDCT/78316004 http://purl.obolibrary.org/obo/CHEBI_28689 A carboxamide derived from a monocarboxylic acid. monocarboxylic acid amide monocarboxylic acid amides http://purl.obolibrary.org/obo/CHEBI_29347 A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. alcohol alcohols http://purl.obolibrary.org/obo/CHEBI_30879 A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism. A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. https://en.wikipedia.org/wiki/Bicalutamide https://www.wikidata.org/wiki/Q1988832 bicalutamide http://purl.obolibrary.org/obo/NCIT_C1599 L02BB03 http://purl.bioontology.org/ontology/MESH/C053541 http://purl.bioontology.org/ontology/SNOMEDCT/386908000 http://purl.obolibrary.org/obo/CHEBI_3090 An orally active synthetic progestational hormone used often in combinations as an oral contraceptive. The actetate salt form of chlormadinone, a synthetic progestin with antiandrogenic and antigonadotropic effects. Chlormadinone acetate (CMA) is a potent progesterone receptor (PR) agonist, a partial androgen receptor (AR) antagonist and a weak glucocorticoid receptor (GR) antagonist. Chlormadinone binds to PRs, which induces the expression of progesterone-responsive genes. In addition, chlormadinone blocks ARs in target organs and reduces the activity of skin 5 alpha-reductase; thus inhibiting androgen production and signaling. Through the negative feedback action on the hypothalamus-pituitary system, chlormadinone also suppresses gonadotropin secretion, which prevents ovarian and adrenal androgen production. Therefore, this agent decreases endometrial thickness, increases the viscosity of cervical mucus, inhibits ovulation and suppresses follicular growth and maturation. https://en.wikipedia.org/wiki/Chlormadinone_acetate https://www.wikidata.org/wiki/Q5102980 chlormadinone acetate http://purl.obolibrary.org/obo/NCIT_C365 CMA http://purl.bioontology.org/ontology/MESH/D002715 http://purl.bioontology.org/ontology/SNOMEDCT/734647009 http://purl.obolibrary.org/obo/CHEBI_31394 The synthetic dipropionate ester of estradiol. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. https://en.wikipedia.org/wiki/Estradiol_dipropionate https://www.wikidata.org/wiki/Q5401761 estradiol dipropionate http://purl.obolibrary.org/obo/NCIT_C29770 EDP http://purl.bioontology.org/ontology/MESH/C023482 http://purl.obolibrary.org/obo/CHEBI_31560 The parenterally-administered synthetic valerate ester of estradiol. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. https://en.wikipedia.org/wiki/Estradiol_valerate https://www.wikidata.org/wiki/Q5401768 estradiol valerate http://id.loc.gov/authorities/subjects/sh95009165 http://purl.obolibrary.org/obo/NCIT_C1090 EV http://purl.bioontology.org/ontology/SNOMEDCT/96350008 http://purl.obolibrary.org/obo/CHEBI_31561 A benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug. https://en.wikipedia.org/wiki/Flunitrazepam https://www.wikidata.org/wiki/Q62947 Rohypnol flunipam roofie ruffie Despite being known as "the date rape drug", the percentage of reported rape and sexual assault cases in which flunitrazepam was involved is small. flunitrazepam http://purl.bioontology.org/ontology/MESH/D005445 http://purl.obolibrary.org/obo/CHEBI_31622 roofie roofied roofies ruffie ruffied ruffies A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups. secondary amine secondary amines http://purl.obolibrary.org/obo/CHEBI_32863 A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. amine amines http://purl.obolibrary.org/obo/CHEBI_32952 An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. https://en.wikipedia.org/wiki/Amide https://en.wikipedia.org/wiki/Category:Amides https://www.wikidata.org/wiki/Q188777 amide amides http://id.loc.gov/authorities/subjects/sh85004464 QD305.A7 QD341.A7 http://purl.obolibrary.org/obo/CHEBI_32988 Any of various derivatives of oxoacids. oxoacid derivative oxoacid derivatives http://purl.obolibrary.org/obo/CHEBI_33241 A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. primary amide primary amides http://purl.obolibrary.org/obo/CHEBI_33256 An organosulfur compound is a compound containing at least one carbon-sulfur bond. organosulfur compound organosulfur compounds http://purl.obolibrary.org/obo/CHEBI_33261 A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms. heteroorganic entity heteroorganic entities http://purl.obolibrary.org/obo/CHEBI_33285 A p-block molecular entity containing any pnictogen. pnictogen molecular entity pnictogen molecular entities http://purl.obolibrary.org/obo/CHEBI_33302 Any p-block molecular entity containing a chalcogen. chalcogen molecular entity chalcogen molecular entities http://purl.obolibrary.org/obo/CHEBI_33304 An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. carboxylic ester carboxylic esters http://purl.obolibrary.org/obo/CHEBI_33308 Any of various derivatives of sulfur oxoacid. sulfur oxoacid derivative sulfur oxoacid derivatives http://purl.obolibrary.org/obo/CHEBI_33424 Any of various derivatives of sulfonic acid. sulfonic acid derivative sulfonic acid derivatives http://purl.obolibrary.org/obo/CHEBI_33552 A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table. main group molecular entity main group molecular entities http://purl.obolibrary.org/obo/CHEBI_33579 A molecular entity contaning carbon. carbon group molecular entity carbon group molecular entities http://purl.obolibrary.org/obo/CHEBI_33582 Any molecule that consists of a series of atoms joined together to form a ring. https://en.wikipedia.org/wiki/Category:Cyclic_compounds https://en.wikipedia.org/wiki/Cyclic_compound cyclic compound cyclic compounds http://purl.obolibrary.org/obo/CHEBI_33595 A cyclic compound having as ring members atoms of the same element only. homocyclic compound homocyclic compounds http://purl.obolibrary.org/obo/CHEBI_33597 A homocyclic compound in which all of the ring members are carbon atoms. carbocyclic compound carbocyclic compounds http://purl.obolibrary.org/obo/CHEBI_33598 A compound having one atom as the only common member of two rings. spiro compound spiro compounds http://purl.obolibrary.org/obo/CHEBI_33599 Compounds which contain two or more rings in their structure. https://en.wikipedia.org/wiki/Polycyclic_compound polycyclic compound polycyclic compounds http://id.loc.gov/authorities/subjects/sh85104607 http://purl.bioontology.org/ontology/MESH/D011083 http://purl.bioontology.org/ontology/SNOMEDCT/417174002 http://purl.obolibrary.org/obo/CHEBI_33635 A molecule that features two fused rings. bicyclic compound bicyclic compounds http://purl.obolibrary.org/obo/CHEBI_33636 A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character. https://en.wikipedia.org/wiki/Category:Aromatic_compounds aromatic compound aromatic compounds http://purl.obolibrary.org/obo/CHEBI_33655 An aromatic compound that is organic. organic aromatic compound organic aromatic compounds http://purl.obolibrary.org/obo/CHEBI_33659 A molecule that features one ring. monocyclic compound monocyclic compounds http://purl.obolibrary.org/obo/CHEBI_33661 A monocyclic compound in which the rings contains at least one skeletal heteroatom. heteromonocyclic compound heteromonocyclic compounds http://purl.obolibrary.org/obo/CHEBI_33670 A polycyclic compound in which at least one of the rings contains at least one non-carbon atom. heteropolycyclic compound heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33671 A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom. heterobicyclic compound heterobicyclic compounds http://purl.obolibrary.org/obo/CHEBI_33672 A main group molecular entity that contains one or more atoms of a p-block element. p-block molecular entity p-block molecular entities http://purl.obolibrary.org/obo/CHEBI_33675 Any of various biological macromolecules which serve to store information, particularly genetic information. information biomacromolecule information biomacromolecules http://purl.obolibrary.org/obo/CHEBI_33695 An organic compound having at least one hydroxy group attached to a carbon atom. organic hydroxy compound organic hydroxy compounds http://purl.obolibrary.org/obo/CHEBI_33822 Any organic molecule that consists of atoms connected in the form of a ring. organic cyclic compound organic cyclic compounds http://purl.obolibrary.org/obo/CHEBI_33832 A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2). heteroarene heteroarenes http://purl.obolibrary.org/obo/CHEBI_33833 An aromatic compound that is benzenoid. benzenoid aromatic compound benzenoid aromatic compounds http://purl.obolibrary.org/obo/CHEBI_33836 A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. https://en.wikipedia.org/wiki/Category:Macromolecules https://en.wikipedia.org/wiki/Macromolecule macromolecule macromolecules http://purl.obolibrary.org/obo/CHEBI_33839 An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols. https://en.wikipedia.org/wiki/Category:Phenols https://en.wikipedia.org/wiki/Phenols phenol phenols http://purl.bioontology.org/ontology/MESH/D019800 http://purl.bioontology.org/ontology/SNOMEDCT/116613007 http://purl.obolibrary.org/obo/CHEBI_33853 A direct metabolite of dehydroepiandrosterone (DHEA) and a precursor for testosterone with immunostimulatory activity and minimal androgenic activity. Androstenediol stimulates the differentiation of hematopoietic precursor cells into leukocytes and platelets, which can counteract the immunotoxicity of radiation exposure. An intermediate in testosterone biosynthesis, found in the testis or the adrenal glands. Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-hydroxysteroid dehydrogenases). https://en.wikipedia.org/wiki/4-Androstenediol 4-androstenediol http://purl.obolibrary.org/obo/NCIT_C95979 androstenediol http://purl.bioontology.org/ontology/MESH/D015114 http://purl.bioontology.org/ontology/SNOMEDCT/103051007 http://purl.obolibrary.org/obo/CHEBI_34386 The cypionate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol cypionate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. https://en.wikipedia.org/wiki/Estradiol_cypionate https://www.wikidata.org/wiki/Q5401760 estradiol 17beta-cyclopentylpropionate estradiol cypionate estradiol 17β-cyclopentylpropionate http://purl.bioontology.org/ontology/SNOMEDCT/109028003 http://purl.obolibrary.org/obo/CHEBI_34745 estradiol cypionate EC Amines that constitute a class of central nervous system stimulants based on the structure of the parent amphetamine 1-phenylpropan-2-amine. Analogs or derivatives of amphetamine. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopressin, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation. amphetamine and amphetamine derivative amphetamine amphetamines http://id.loc.gov/authorities/subjects/sh85004595 RC568.A45 RM666.A493 http://purl.bioontology.org/ontology/MEDDRA/10063227 http://purl.bioontology.org/ontology/MESH/D000662 http://purl.obolibrary.org/obo/CHEBI_35338 amphetamine and amphetamine derivative http://purl.bioontology.org/ontology/SNOMEDCT/412035000 Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene, so may be considered as triterpenoids. https://en.wikipedia.org/wiki/Category:Steroids https://en.wikipedia.org/wiki/Steroid steroid steroids http://purl.bioontology.org/ontology/SNOMEDCT/116566001 http://purl.obolibrary.org/obo/CHEBI_35341 A 17-hydroxy steroid in which the hydroxy group at position 17 has a beta-configuration. 17beta-hydroxy steroid 17β-hydroxy steroid 17β-hydroxy steroids http://purl.obolibrary.org/obo/CHEBI_35343 17beta-hydroxy steroid 17beta-hydroxy steroids A steroid contaning a hydroxy group. hydroxy steroid hydroxy steroids http://purl.obolibrary.org/obo/CHEBI_35350 Any heteroorganic entity containing at least one carbon-nitrogen bond. organonitrogen compound organonitrogen compounds http://purl.obolibrary.org/obo/CHEBI_35352 A group of compounds that contain the structure SO2NH2. An amide of a sulfonic acid RS(=O)2NR'2. https://en.wikipedia.org/wiki/Category:Sulfonamides https://en.wikipedia.org/wiki/Sulfonamide https://www.wikidata.org/wiki/Q3208529 sulfonamide sulfonamides G04BE03 http://purl.bioontology.org/ontology/MESH/D013449 http://purl.bioontology.org/ontology/SNOMEDCT/387406002 http://purl.obolibrary.org/obo/CHEBI_35358 Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group. fluorobenzene fluorobenzenes http://purl.obolibrary.org/obo/CHEBI_35496 A compound which inhibits or antagonises the biosynthesis or actions of androgens. Substances that inhibit or antagonize the biosynthesis or biologic effects of androgens by either antagonizing the responsiveness of androgen sensitive tissues or competing with their binding sites. https://en.wikipedia.org/wiki/Antiandrogen https://en.wikipedia.org/wiki/Category:Antiandrogens https://www.wikidata.org/wiki/Q574820 androgen blocker anti-androgen antiandrogen androgen antagonist androgen antagonists http://id.loc.gov/authorities/subjects/sh85005628 http://purl.obolibrary.org/obo/NCIT_C242 L02BB http://purl.bioontology.org/ontology/SNOMEDCT/103024009 http://purl.obolibrary.org/obo/CHEBI_35497 androgen blocker androgen blockers anti-androgen anti-androgens antiandrogen antiandrogens Any ether in which the oxygen is attached to at least one aryl substituent. https://en.wikipedia.org/wiki/Category:Aromatic_ethers aromatic ether aromatic ethers http://purl.obolibrary.org/obo/CHEBI_35618 A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it. secondary alcohol secondary alcohols http://purl.obolibrary.org/obo/CHEBI_35681 A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter. https://en.wikipedia.org/wiki/Category:Esters https://en.wikipedia.org/wiki/Ester https://www.wikidata.org/wiki/Q101487 ester esters http://purl.bioontology.org/ontology/SNOMEDCT/45120003 http://purl.obolibrary.org/obo/CHEBI_35701 An aza-steroid is a steroid where in the carbon skeleton a carbon atom is replaced by nitrogen. aza-steroid aza-steroids http://purl.obolibrary.org/obo/CHEBI_35726 A carboxylic ester in which the carboxylic acid component can be any fatty acid. fatty acid ester fatty acid esters http://purl.obolibrary.org/obo/CHEBI_35748 Any steroid having a ketone functional group. https://en.wikipedia.org/wiki/Ketosteroid oxosteroid ketosteroid oxo steroid oxo steroids http://purl.bioontology.org/ontology/MESH/D007664 http://purl.obolibrary.org/obo/CHEBI_35789 oxosteroid oxosteroids ketosteroid ketosteroids A compound that is an imidazopyrimidine. https://en.wikipedia.org/wiki/Category:Imidazopyrimidines imidazopyrimidine imidazopyrimidines http://purl.obolibrary.org/obo/CHEBI_35875 A steroid ester obtained by formal condensation of the carboxy group of any carboxylic acid with the 3-hydroxy group of a sterol. sterol ester sterol esters http://purl.obolibrary.org/obo/CHEBI_35915 A drug used to treat or prevent microbial infections. antimicrobial drug antimicrobial drugs http://purl.obolibrary.org/obo/CHEBI_36043 A substance used in the prophylaxis or therapy of virus diseases. https://en.wikipedia.org/wiki/Antiviral_drug https://www.wikidata.org/wiki/Q846227 anti-viral drug antiviral drug antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044 anti-viral drug anti-viral drugs Esters of benzoic acid or substituted benzoic acids. benzoate ester benzoate esters http://purl.obolibrary.org/obo/CHEBI_36054 A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome. A group of complex organic macromolecules composed of one or more chains (linear polymers) of alpha-L-amino acids linked by peptide bonds and ranging in size from a few thousand to over 1 million Daltons. Proteins are fundamental genetically encoded components of living cells with specific structures and functions dictated by amino acid sequence. A protein is an organic polymer that is composed of one or more linear polymers of amino acids. https://en.wikipedia.org/wiki/Category:Proteins https://en.wikipedia.org/wiki/Protein https://www.wikidata.org/wiki/Q8054 protein proteins http://id.loc.gov/authorities/subjects/sh85107666 QD431-QD431.7 QP551-QP552 http://purl.org/sig/ont/fma/fma67257 http://purl.obolibrary.org/obo/NCIT_C17021 http://purl.bioontology.org/ontology/SNOMEDCT/88878007 http://purl.obolibrary.org/obo/CHEBI_36080 A cyclic ketone in which the carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system. alicyclic ketone alicyclic ketones http://purl.obolibrary.org/obo/CHEBI_36132 Any molecular entity consisting of more than one atom. polyatomic entity polyatomic entities http://purl.obolibrary.org/obo/CHEBI_36357 Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. https://en.wikipedia.org/wiki/Carbonyl_group#Carbonyl_compounds https://en.wikipedia.org/wiki/Category:Carbonyl_compounds carbonyl compound carbonyl compounds http://purl.obolibrary.org/obo/CHEBI_36586 Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element. organic oxo compound organic oxo compounds http://purl.obolibrary.org/obo/CHEBI_36587 An organochlorine compound is a compound containing at least one carbon-chlorine bond. organochlorine compound organochlorine compounds http://purl.obolibrary.org/obo/CHEBI_36683 A compound containing at least one carbon-halogen bond. organohalogen compound organohalogen compounds http://purl.obolibrary.org/obo/CHEBI_36684 Any of a class of steroid hormones that are produced in the adrenal cortex. adrenal cortex hormone corticosteroid hormone corticosteroid hormones http://purl.obolibrary.org/obo/CHEBI_36699 adrenal cortex hormone adrenal cortex hormones Any hydroxy steroid carrying a hydroxy group at position 3. 3-hydroxy steroid 3-hydroxy steroids http://purl.obolibrary.org/obo/CHEBI_36834 A 3-hydroxy steroid in which the 3-hydroxy substituent is in the beta-position. 3beta-hydroxy steroid 3β-hydroxy steroid 3β-hydroxy steroids http://purl.obolibrary.org/obo/CHEBI_36836 3beta-hydroxy steroid 3beta-hydroxy steroids A hydroxy steroid carrying a hydroxy group at position 17. 17-hydroxy steroid 17-hydroxy steroids http://purl.obolibrary.org/obo/CHEBI_36838 Any hydroxy steroid carrying a hydroxy group at position 16. 16-hydroxy steroid 16-hydroxy steroids http://purl.obolibrary.org/obo/CHEBI_36840 An oxo steroid carrying an oxo group at position 20. 20-oxo steroid 20-oxo steroids http://purl.obolibrary.org/obo/CHEBI_36885 An organochalcogen compound is a compound containing at least one carbon-chalcogen bond. organochalcogen compound organochalcogen compounds http://purl.obolibrary.org/obo/CHEBI_36962 An organochalcogen compound containing at least one carbon-oxygen bond. organooxygen compound organooxygen compounds http://purl.obolibrary.org/obo/CHEBI_36963 An organofluorine compound is a compound containing at least one carbon-fluorine bond. organofluorine compound organofluorine compounds http://purl.obolibrary.org/obo/CHEBI_37143 Any of various compounds comprising a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. https://en.wikipedia.org/wiki/Category:Tropane_alkaloids https://en.wikipedia.org/wiki/Tropane_alkaloid https://www.wikidata.org/wiki/Q2832080 tropane alkaloid tropane alkaloids http://purl.obolibrary.org/obo/CHEBI_37332 A molecular entity consisting of two or more chemical elements. heteroatomic molecular entity heteroatomic molecular entities http://purl.obolibrary.org/obo/CHEBI_37577 Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements. halide halides http://purl.obolibrary.org/obo/CHEBI_37578 An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom. https://en.wikipedia.org/wiki/Carboxamide https://en.wikipedia.org/wiki/Category:Carboxamides https://www.wikidata.org/wiki/Q355679 carboxamide carboxamides http://purl.obolibrary.org/obo/CHEBI_37622 A spiro compound in which at least one of the cyclic components is an oxygen heterocyle. oxaspiro compound oxaspiro compounds http://purl.obolibrary.org/obo/CHEBI_37948 A macromolecule derived from one species of (real, implicit or hypothetical) monomer. homopolymer macromolecule homopolymer macromolecules http://purl.obolibrary.org/obo/CHEBI_37997 Any aminopurine that has amino substituents at positions 2 and 6, and their substituted derivatives. 2,6-diaminopurine 2,6-diaminopurines http://purl.obolibrary.org/obo/CHEBI_38001 Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms. organonitrogen heterocyclic compound organonitrogen heterocyclic compounds http://purl.obolibrary.org/obo/CHEBI_38101 Any organic heterocyclic compound containing at least one ring oxygen atom. oxacycle oxacycles http://purl.obolibrary.org/obo/CHEBI_38104 An organic compound with four different ring structures. organic heterotetracyclic compound organic heterotetracyclic compounds http://purl.obolibrary.org/obo/CHEBI_38163 An organic compound that is heteropolycyclic. organic heteropolycyclic compound organic heteropolycyclic compounds http://purl.obolibrary.org/obo/CHEBI_38166 Any of various compounds considered imidazolidines. imidazolidine imidazolidines http://purl.obolibrary.org/obo/CHEBI_38261 Any of various compounds considered azabicycloalkanes. azabicycloalkane azabicycloalkanes http://purl.obolibrary.org/obo/CHEBI_38295 A compound with an aromatic ring and a heterocycle with a methylenedioxy group. https://en.wikipedia.org/wiki/Category:Benzodioxoles benzodioxole benzodioxoles http://purl.obolibrary.org/obo/CHEBI_38298 A pyrazolidine. diazolidine diazolidines http://purl.obolibrary.org/obo/CHEBI_38304 Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure). diazine diazines http://purl.obolibrary.org/obo/CHEBI_38313 A pyrimidine carrying one or more oxo substituents. pyrimidone pyrimidones http://purl.obolibrary.org/obo/CHEBI_38337 An alkaloid with a phenethylamine group. phenethylamine alkaloid phenethylamine alkaloids http://purl.obolibrary.org/obo/CHEBI_38605 Any of a series of isomeric heterocyclic chemical compounds with the molecular formula C6H5N3. They form the central core of a variety of more complex chemical compounds including some pharmaceuticals and pesticides. https://en.wikipedia.org/wiki/Category:Pyrazolopyrimidines https://en.wikipedia.org/wiki/Pyrazolopyrimidine pyrazolopyrimidine pyrazolopyrimidines http://purl.obolibrary.org/obo/CHEBI_38669 Any compound having a pyrimidine as part of its structure. pyrimidine pyrimidines http://purl.obolibrary.org/obo/CHEBI_39447 A ketone that is cycle. The simplest class have the formula (CH2)nCO, where n varies from 2 for cyclopropanone to the teens. https://en.wikipedia.org/wiki/Ketone#Cyclic_ketones cyclic ketone cyclic ketones http://purl.bioontology.org/ontology/SNOMEDCT/300046003 http://purl.obolibrary.org/obo/CHEBI_3992 A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. A synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. https://en.wikipedia.org/wiki/Diethylstilbestrol diethylstilbestrol http://id.loc.gov/authorities/subjects/sh85037869 http://purl.obolibrary.org/obo/NCIT_C433 DES L02AA01 http://purl.bioontology.org/ontology/MESH/D004054 http://purl.bioontology.org/ontology/SNOMEDCT/396026002 http://purl.obolibrary.org/obo/CHEBI_41922 A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection. https://en.wikipedia.org/wiki/Abacavir https://www.wikidata.org/wiki/Q304330 abacavir http://purl.obolibrary.org/obo/HIV_5685 http://purl.obolibrary.org/obo/NCIT_C61523 ABC http://purl.bioontology.org/ontology/MESH/C106538 http://purl.bioontology.org/ontology/SNOMEDCT/387005008 http://purl.obolibrary.org/obo/CHEBI_421707 Any of various chemical compounds containing a nitrite ester. https://www.wikidata.org/wiki/Q16683253 nitrite ester nitrite esters http://purl.obolibrary.org/obo/CHEBI_46649 Any carboxylic ester where the carboxylic acid component is acetic acid. acetate ester acetate esters http://purl.obolibrary.org/obo/CHEBI_47622 Any oxo steroid where an oxo substituent is located at position 3. 3-oxo steroid 3-oxo steroids http://purl.obolibrary.org/obo/CHEBI_47788 An ester of a steroid. https://en.wikipedia.org/wiki/Category:Steroid_esters https://en.wikipedia.org/wiki/Steroid_ester https://www.wikidata.org/wiki/Q24883081 steroid ester steroid esters http://purl.obolibrary.org/obo/CHEBI_47880 A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position. 3-oxo-Delta(4) steroid 3-oxo-Δ4 steroid 3-oxo-Δ4 steroids http://purl.obolibrary.org/obo/CHEBI_47909 3-oxo-Delta(4) steroid 3-oxo-Delta(4) steroids A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. Substances that inhibit or antagonize the function of the endocrine glands, the biosynthesis or biological effect of secreted hormones. https://en.wikipedia.org/wiki/Hormone_antagonist https://www.wikidata.org/wiki/Q16875676 hormone blocker anti-hormone antihormone hormone antagonist hormone antagonists http://homosaurus.org/v2/hormoneBlockers http://id.loc.gov/authorities/subjects/sh85061977 http://purl.obolibrary.org/obo/NCIT_C547 http://purl.bioontology.org/ontology/SNOMEDCT/103022008 http://purl.obolibrary.org/obo/CHEBI_49020 hormone blocker hormone blockers anti-hormone anti-hormones antihormone antihormones http://homosaurus.org/v2/hormoneBlockers A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration. https://en.wikipedia.org/wiki/Ethinylestradiol 17alpha-ethynylestradiol 17α-ethynylestradiol http://id.loc.gov/authorities/subjects/sh85045126 http://purl.obolibrary.org/obo/NCIT_C486 ethynylestradiol http://purl.obolibrary.org/obo/CHEBI_4903 ethynylestradiol ethinyl estradiol A chemical substance that prevents or reduces the probability of conception. contraceptive agent hormonal contraceptive contraceptive drug contraceptive drugs contraceptive http://purl.obolibrary.org/obo/CHEBI_49323 hormonal contraceptive hormonal contraceptive for systemic use hormonal contraceptives for systemic use hormonal contraceptives G03A contraceptive contraceptives A compound, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. An agent taken orally to prevent conception. contraceptive oral pill oral contraceptive pill oral contraceptive oral contraceptives http://purl.obolibrary.org/obo/NCIT_C389 OC http://purl.bioontology.org/ontology/MEDDRA/10030971 http://purl.obolibrary.org/obo/CHEBI_49325 contraceptive oral pill contraceptive oral pills oral contraceptive pill https://en.wikipedia.org/wiki/Oral_contraceptive_pill OCPs oral contraceptive pills OCP A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. organic amino compound organic amino compounds http://purl.obolibrary.org/obo/CHEBI_50047 Any hormone that is responsible for controlling sexual characteristics and reproductive function. female sex hormone male sex hormone https://en.wikipedia.org/wiki/Category:Sex_hormones gonadal hormone sex hormone sex hormones http://id.loc.gov/authorities/subjects/sh85061983 QP572.S4 http://purl.bioontology.org/ontology/SNOMEDCT/312263009 http://purl.obolibrary.org/obo/CHEBI_50112 female sex hormone female sex hormones male sex hormone male sex hormones gonadal hormone gonadal hormones http://purl.bioontology.org/ontology/SNOMEDCT/81118006 A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors. https://en.wikipedia.org/wiki/Androgen androgen androgens http://id.loc.gov/authorities/subjects/sh85004919 QP572.A5 http://purl.org/sig/ont/fma/fma83375 http://purl.obolibrary.org/obo/NCIT_C2298 http://purl.bioontology.org/ontology/SNOMEDCT/84629008 http://purl.obolibrary.org/obo/CHEBI_50113 A hormone that stimulates or controls the development and maintenance of feminine sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens. https://en.wikipedia.org/wiki/Estrogen estrogen estrogens http://homosaurus.org/v2/estrogen http://id.loc.gov/authorities/subjects/sh85045012 QP572.E85 http://purl.org/sig/ont/fma/fma83376 http://purl.obolibrary.org/obo/NCIT_C2293 E http://purl.bioontology.org/ontology/MEDDRA/10015514 http://purl.bioontology.org/ontology/SNOMEDCT/734775001 http://purl.obolibrary.org/obo/CHEBI_50114 http://homosaurus.org/v2/estrogen Any steroid based on an androstane skeleton and its derivatives. androstanoid androstanoids http://purl.obolibrary.org/obo/CHEBI_50402 Any compound containing the thiocarbonyl group, C=S. thiocarbonyl compound thiocarbonyl compounds http://purl.obolibrary.org/obo/CHEBI_50492 An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position. alkyl alcohol alkyl alcohols http://purl.obolibrary.org/obo/CHEBI_50584 A medication used mainly to treat an enlarged prostate or hair loss in men. It can also be used to treat excessive hair growth in women and as a part of hormone therapy for transgender women. A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation. An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia. An orally active 3-oxo-5-alpha-steroid 4-dehydrogenase inhibitor. It is used as a surgical alternative for treatment of benign prostatic hyperplasia. https://en.wikipedia.org/wiki/Finasteride https://www.wikidata.org/wiki/Q424167 finasteride http://purl.obolibrary.org/obo/NCIT_C1099 http://purl.bioontology.org/ontology/MESH/D018120 http://purl.bioontology.org/ontology/SNOMEDCT/386963006 http://purl.obolibrary.org/obo/CHEBI_5062 A substance used either in the prevention or facilitation of pregnancy. reproductive control agent reproductive control drug reproductive control drugs http://purl.obolibrary.org/obo/CHEBI_50689 reproductive control agent reproductive control agents Chemical substances that interrupt pregnancy after implantation. https://en.wikipedia.org/wiki/Abortifacient https://en.wikipedia.org/wiki/Category:Abortifacients https://www.wikidata.org/wiki/Q323047 aborticide abortifacient agent abortifacient drug abortifacient abortifacients http://id.loc.gov/authorities/subjects/sh85000195 RG734.4-RG734.5 http://purl.bioontology.org/ontology/MESH/D000019 http://purl.bioontology.org/ontology/SNOMEDCT/6716006 http://purl.obolibrary.org/obo/CHEBI_50691 aborticide aborticides abortifacient agent abortifacient agents abortifacient drug abortifacient drugs An agent with anti-androgen and progestational properties. It shows competitive binding with dihydrotestosterone at androgen receptor sites. The acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductions in testicular androgen secretion and serum testosterone levels. Treatment with cyproterone alone results in incomplete suppression of serum testosterone levels. https://en.wikipedia.org/wiki/Cyproterone_acetate https://www.wikidata.org/wiki/Q426185 cyproterone acetate http://purl.obolibrary.org/obo/NCIT_C1059 CPA http://purl.bioontology.org/ontology/MESH/D017373 http://purl.bioontology.org/ontology/SNOMEDCT/126120000 http://purl.obolibrary.org/obo/CHEBI_50743 A salt of citric acid. citrate salt citrate salts http://purl.obolibrary.org/obo/CHEBI_50744 A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone. Substances that produce effects similar to those of progesterone, the only natural progestogen. All other progestogens are synthetic and are often referred to as progestins. All progestogens have antiestrogenic and antigonadotropic properties. https://en.wikipedia.org/wiki/Progestogen gestagen progestagen progestogen progestogens http://purl.obolibrary.org/obo/NCIT_C2296 http://purl.obolibrary.org/obo/CHEBI_50745 gestagen gestagens progestagen progestagens A compound which inhibits or antagonises the biosynthesis or actions of estrogens. Substances that inhibit or antagonize the biosynthesis or biologic effects of estrogens by either antagonizing the responsiveness of estrogen sensitive tissues or competing with their binding sites. https://en.wikipedia.org/wiki/Antiestrogen https://en.wikipedia.org/wiki/Category:Antiestrogens https://www.wikidata.org/wiki/Q4774709 anti-estrogen antiestrogen estrogen antagonist estrogen antagonists http://purl.obolibrary.org/obo/NCIT_C481 http://purl.obolibrary.org/obo/CHEBI_50837 anti-estrogen anti-estrogens antiestrogen antiestrogens A synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity. Drospirenone binds to the progesterone receptor, the resulting complex becomes activated and binds to specific sites on DNA. This results in a suppression of LH activity and an inhibition of ovulation as well as an alteration in the cervical mucus and endometrium. This leads to an increased difficulty of sperm entry into the uterus and implantation. This drug is used in oral contraceptives. https://en.wikipedia.org/wiki/Drospirenone https://www.wikidata.org/wiki/Q419646 drospirenone http://purl.obolibrary.org/obo/NCIT_C47502 http://purl.bioontology.org/ontology/MESH/C035144 http://purl.bioontology.org/ontology/SNOMEDCT/410919000 http://purl.obolibrary.org/obo/CHEBI_50838 A natural or synthetic analogue of the hormones secreted by the adrenal gland. Hormones synthesized in the cortex of the adrenal gland and consist of two subclasses, glucocorticoids (carbohydrate regulation) and mineralocorticoids (electrolyte regulation). https://en.wikipedia.org/wiki/Category:Corticosteroids https://en.wikipedia.org/wiki/Corticosteroid https://www.wikidata.org/wiki/Q210420 corticosteroid corticosteroids http://purl.obolibrary.org/obo/NCIT_C2322 http://purl.obolibrary.org/obo/CHEBI_50858 Any molecular entity that contains carbon. organic molecular entity organic molecular entities http://purl.obolibrary.org/obo/CHEBI_50860 An ester of enanthate. enanthate ester enanthate esters http://purl.obolibrary.org/obo/CHEBI_50898 A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group. primary amino compound primary amino compounds http://purl.obolibrary.org/obo/CHEBI_50994 A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. secondary amino compound secondary amino compounds http://purl.obolibrary.org/obo/CHEBI_50995 A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups. tertiary amino compound tertiary amino compounds http://purl.obolibrary.org/obo/CHEBI_50996 A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. hormone agonist hormone agonists http://purl.obolibrary.org/obo/CHEBI_51060 A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. hormone receptor modulator hormone receptor modulators http://purl.obolibrary.org/obo/CHEBI_51061 A molecular entity containing any nitrogen. nitrogen molecular entity nitrogen molecular entities http://purl.obolibrary.org/obo/CHEBI_51143 A compound of general formula RC(=O)SR'. thioester thioesters http://purl.obolibrary.org/obo/CHEBI_51277 A toluidine derivative and a nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2-hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest or transient tumor regression. https://en.wikipedia.org/wiki/Flutamide https://www.wikidata.org/wiki/Q418669 flutamide http://purl.obolibrary.org/obo/NCIT_C509 L02BB01 http://purl.bioontology.org/ontology/MESH/D005485 http://purl.bioontology.org/ontology/SNOMEDCT/387587007 http://purl.obolibrary.org/obo/CHEBI_5132 Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups. methoxybenzene methoxybenzenes http://purl.obolibrary.org/obo/CHEBI_51683 An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position. https://en.wikipedia.org/wiki/Category:Enones https://en.wikipedia.org/wiki/Enone enone enones http://purl.obolibrary.org/obo/CHEBI_51689 A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. alpha,beta-unsaturated ketone α,β-unsaturated ketone α,β-unsaturated ketones http://purl.obolibrary.org/obo/CHEBI_51721 alpha,beta-unsaturated ketone alpha,beta-unsaturated ketones An organic compound that is polycyclic. https://en.wikipedia.org/wiki/Category:Polycyclic_organic_compounds polycyclic organic compound organic polycyclic compound organic polycyclic compounds http://purl.obolibrary.org/obo/CHEBI_51958 polycyclic organic compound polycyclic organic compounds An aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland. https://en.wikipedia.org/wiki/Dutasteride https://www.wikidata.org/wiki/Q424760 dutasteride http://purl.obolibrary.org/obo/NCIT_C47503 G04CB02 http://purl.bioontology.org/ontology/MESH/D000068538 http://purl.bioontology.org/ontology/SNOMEDCT/385572003 http://purl.obolibrary.org/obo/CHEBI_521033 A macromolecule composed of repeating alkane or substituted alkane units. poly(alkylene) macromolecule polyalkylene macromolecule polyalkylene macromolecules http://purl.obolibrary.org/obo/CHEBI_53225 poly(alkylene) macromolecule poly(alkylene) macromolecules A macromolecule composed of ethane or substituted ethane units. polyethylene macromolecule polyethylene macromolecules http://purl.obolibrary.org/obo/CHEBI_53226 A macromolecule composed of repeating -CHR-CH2- units. vinyl polymer macromolecule vinyl polymer macromolecules http://purl.obolibrary.org/obo/CHEBI_53242 A polymer composed of repeating chloroethyl units. A polyvinyl resin used extensively in the manufacture of plastics, including medical devices, tubing, and other packaging. It is also used as a rubber substitute. https://en.wikipedia.org/wiki/Polyvinyl_chloride https://www.wikidata.org/wiki/Q146368 polyvinylchloride polyvinyl chloride http://id.loc.gov/authorities/subjects/sh85104742 PVC http://purl.bioontology.org/ontology/MESH/D011143 http://purl.bioontology.org/ontology/SNOMEDCT/35233000 http://purl.obolibrary.org/obo/CHEBI_53243 A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. A synthetic long-acting agonist of gonadotropin-releasing hormone. Goserelin is used in treatments of malignant neoplasms of the prostate, uterine fibromas, and metastatic breast cancer. https://en.wikipedia.org/wiki/Goserelin https://www.wikidata.org/wiki/Q1992653 goserelin http://purl.obolibrary.org/obo/NCIT_C1374 L02AE03 http://purl.bioontology.org/ontology/MESH/D017273 http://purl.bioontology.org/ontology/SNOMEDCT/108771008 http://purl.obolibrary.org/obo/CHEBI_5523 An imidazolidine containing one or more oxo groups. imidazolidinone imidazolidinones http://purl.obolibrary.org/obo/CHEBI_55370 A cyclic compound having as ring members atoms of at least two different elements. heterocyclic compound heterocyclic compounds http://purl.obolibrary.org/obo/CHEBI_5686 A long-acting, synthetic nonapeptide analog of gonadotropin-releasing hormone (GnRH) with potential anti-tumor activity. Upon administration, histrelin binds to and activates GnRH receptors; prolonged administration results in pituitary GnRH receptor desensitization and inhibition of follicle stimulating hormone (FSH) and luteinizing hormone (LH) secretion, leading to a significant decline in testosterone production in males and may inhibit androgen receptor-positive tumor progression; in cisgender women, prolonged administration results in decreased estradiol production. An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, 1-benzyl-D-histidyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the diacetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. https://en.wikipedia.org/wiki/Histrelin https://www.wikidata.org/wiki/Q5871149 histrelin http://purl.obolibrary.org/obo/NCIT_C74270 http://purl.bioontology.org/ontology/MESH/C029256 http://purl.bioontology.org/ontology/SNOMEDCT/109049002 http://purl.obolibrary.org/obo/CHEBI_5739 A phosphodiesterase type-5 inhibitor; vasodilator agent and urological agent that is used in the treatment of erectile dysfunction and primary pulmonary hypertension. The citrate salt form of sildenafil, an orally bioavailable pyrazolopyrimidinone derivative structurally related to zaprinast, with vasodilating and potential anti-inflammatory activities. Upon oral administration, sildenafil selectively targets and inhibits cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), thereby inhibiting the PDE5-mediated degradation of cGMP found in smooth muscle and increasing cGMP availability. This results in prolonged smooth muscle relaxation in the corpus cavernosum of the penis, thereby causing vasodilation, blood engorgement and a prolonged penile erection. In the smooth muscle of the pulmonary vasculature, the increase in cGMP results in smooth muscle relaxation, vasodilation of the pulmonary vascular bed, relieving pulmonary hypertension and increasing blood flow in the lungs. In addition, sildenafil may reduce airway inflammation and mucus production. The citrate salt of sildenafil. sildenafil citrate http://purl.obolibrary.org/obo/NCIT_C26670 http://purl.bioontology.org/ontology/MESH/D000068677 http://purl.bioontology.org/ontology/SNOMEDCT/108482004 http://purl.obolibrary.org/obo/CHEBI_58987 The sulfur analogue of 'acetal'. The term includes monothioacetals having the structure R2C(OR')(SR') (subclass monothioketals, R =/= H); and dithioacetals having the structure R2C(SR')2 (subclass dithioketals, R =/= H, R' =/= H). thioacetal thioacetals http://purl.obolibrary.org/obo/CHEBI_59792 A thioacetal having the structure R2C(OR')(SR'). The term includes monothioketals, R =/= H, as a subclass. monothioacetal monothioacetals http://purl.obolibrary.org/obo/CHEBI_59793 A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types. https://en.wikipedia.org/wiki/Category:Chemical_substances https://en.wikipedia.org/wiki/Chemical_substance https://www.wikidata.org/wiki/Q79529 chemical substance chemical substances http://purl.obolibrary.org/obo/CHEBI_59999 A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind. https://en.wikipedia.org/wiki/Category:Chemical_mixtures https://en.wikipedia.org/wiki/Mixture https://www.wikidata.org/wiki/Q169336 chemical mixture mixture mixtures http://purl.obolibrary.org/obo/NCIT_C45305 http://purl.obolibrary.org/obo/CHEBI_60004 chemical mixture chemical mixtures A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc. https://en.wikipedia.org/wiki/Category:Polymers https://en.wikipedia.org/wiki/Polymer https://www.wikidata.org/wiki/Q81163 polymer polymers http://id.loc.gov/authorities/subjects/sh85104660 QC173.4.P65 QD380-QD388 TA455.P58 http://purl.obolibrary.org/obo/NCIT_C48803 http://purl.bioontology.org/ontology/SNOMEDCT/412155002 http://purl.obolibrary.org/obo/CHEBI_60027 One of a class of naturally occurring alkaloids with a structure based on that of ergoline. ergoline alkaloid ergoline alkaloids http://purl.obolibrary.org/obo/CHEBI_60529 An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells. nucleoside analogue nucleoside analogues http://purl.obolibrary.org/obo/CHEBI_60783 A racemate is an equimolar mixture of a pair of enantiomers. An equimolar mixture of two enantiomers. A racemate is optically inactive. https://en.wikipedia.org/wiki/Racemic_mixture https://www.wikidata.org/wiki/Q467717 racemic mixture racemate racemates http://purl.obolibrary.org/obo/NCIT_C103198 http://purl.obolibrary.org/obo/CHEBI_60911 A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors and may interact with sigma receptors. A cyclohexanone derivative with analgesic and anesthetic properties. Although its mechanism of action is not well understood, ketamine appears exerts complex pharmacological actions including inhibition of biogenic amine uptake, binding to opioid receptors, and inhibition of N-methyl D-aspartate (NMDA) receptors. Because of the involvement of spinal NMDA receptors in the process of central sensitization, this agent may reduce pain perception and induce sedation. A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group. https://en.wikipedia.org/wiki/Ketamine https://www.wikidata.org/wiki/Q243547 Ketamine induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include sedation in intensive care and treatment of pain and depression. Heart function, breathing, and airway reflexes generally remain functional. Effects typically begin within five minutes when given by injection, and last up to approximately 25 minutes. ketamine http://id.loc.gov/authorities/subjects/sh92004206 RD86.K4 http://purl.obolibrary.org/obo/NCIT_C61797 N01AX03 http://purl.bioontology.org/ontology/MESH/D007649 http://purl.bioontology.org/ontology/SNOMEDCT/373464007 http://purl.obolibrary.org/obo/CHEBI_6121 A steroid that has a structure based on a 21-carbon (pregnane) skeleton. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure. C21-steroid C21-steroids http://purl.obolibrary.org/obo/CHEBI_61313 A polymer, composed of polysiloxane macromolecules. polysiloxane polymer polysiloxane polymers polysiloxane http://purl.obolibrary.org/obo/CHEBI_61458 polysiloxane polysiloxanes A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. A polysiloxane polymer, composed of silicone macromolecules. A synthetic gel that is used as an outer coating on breast implants and as the inside filling of some implants. https://en.wikipedia.org/wiki/Category:Silicones https://en.wikipedia.org/wiki/Silicone https://www.wikidata.org/wiki/Q146439 silicone polymer silicone polymers http://id.loc.gov/authorities/subjects/sh85122534 QD383.S54 http://purl.obolibrary.org/obo/NCIT_C28189 silicone http://purl.bioontology.org/ontology/MESH/D012828 http://purl.bioontology.org/ontology/SNOMEDCT/13652007 http://purl.obolibrary.org/obo/CHEBI_61459 silicone silicones Any organic molecular entity derived from a fatty acid. fatty acid derivative fatty acid derivatives http://purl.obolibrary.org/obo/CHEBI_61697 An ester where the ester linkage is bonded directly to an aromatic system. aromatic ester aromatic esters http://purl.obolibrary.org/obo/CHEBI_62732 An amide in which the amide linkage is bonded directly to an aromatic system. aromatic amide aromatic amides http://purl.obolibrary.org/obo/CHEBI_62733 A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity. glycosyl compound glycosyl compounds http://purl.obolibrary.org/obo/CHEBI_63161 Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds. carbohydrate derivative carbohydrate derivatives http://purl.obolibrary.org/obo/CHEBI_63299 A type of medication which affects gonadotropins and sex hormones. They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of hormone-sensitive cancers such as prostate cancer and breast cancer, certain gynecological disorders like heavy periods and endometriosis, high testosterone levels in women, early puberty in children, as a part of transgender hormone therapy, and to delay puberty in transgender youth among other uses. Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response. https://en.wikipedia.org/wiki/Gonadotropin-releasing_hormone_agonist https://www.wikidata.org/wiki/Q3606696 gonadotrophin-releasing hormone agonist gonadotropin releasing hormone agonist gonadotropin releasing hormone agonists GnRH agonist GnRH-A http://purl.obolibrary.org/obo/CHEBI_63533 gonadotrophin-releasing hormone agonist gonadotrophin-releasing hormone agonists GnRH agonist GnRH agonists A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B. http://purl.obolibrary.org/obo/HIV_5673 https://en.wikipedia.org/wiki/Lamivudine https://www.wikidata.org/wiki/Q422631 3TC lamivudine http://purl.obolibrary.org/obo/NCIT_C1471 http://purl.bioontology.org/ontology/MESH/D019259 http://purl.bioontology.org/ontology/SNOMEDCT/386897000 http://purl.obolibrary.org/obo/CHEBI_63577 A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone. https://en.wikipedia.org/wiki/Triptorelin https://www.wikidata.org/wiki/Q1992452 triptorelin http://purl.obolibrary.org/obo/NCIT_C1267 http://purl.bioontology.org/ontology/SNOMEDCT/395915003 http://purl.obolibrary.org/obo/CHEBI_63633 A potent synthetic long-acting agonist of gonadotropin-releasing hormone that regulates the synthesis and release of pituitary gonadotropins, luteinizing hormone and follice stimulating hormone. A synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors. Continuous, prolonged administration of leuprolide in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. This agent reduces testosterone production to castration levels and may inhibit androgen receptor-positive tumor progression. An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-leucyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the acetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. https://en.wikipedia.org/wiki/Leuprorelin https://www.wikidata.org/wiki/Q907160 leuprorelin leuprolide http://purl.obolibrary.org/obo/NCIT_C62042 http://purl.bioontology.org/ontology/MESH/D016729 http://purl.bioontology.org/ontology/SNOMEDCT/397198002 http://purl.obolibrary.org/obo/CHEBI_6427 A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone. C21-steroid hormone C21-steroid hormones http://purl.obolibrary.org/obo/CHEBI_64600 An ergoline alkaloid arising from formal condensation of lysergic acid with diethylamine. Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood. https://en.wikipedia.org/wiki/Category:Lysergic_acid_diethylamide https://en.wikipedia.org/wiki/Lysergic_acid_diethylamide https://www.wikidata.org/wiki/Q23118 acid lysergic acid diethylamide http://id.loc.gov/authorities/subjects/sh85079185 BF209.L9 HV5822.5.L9 RC483.5.L9 RM666.L88 LSD http://purl.bioontology.org/ontology/MESH/D008238 http://purl.bioontology.org/ontology/SNOMEDCT/15698006 http://purl.obolibrary.org/obo/CHEBI_6605 acid A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms. A synthetic, acetate derivative of the sex hormone progesterone. https://en.wikipedia.org/wiki/Medroxyprogesterone_acetate https://www.wikidata.org/wiki/Q2823834 medroxyprogesterone acetate http://purl.obolibrary.org/obo/NCIT_C1155 http://purl.bioontology.org/ontology/MESH/D017258 http://purl.bioontology.org/ontology/SNOMEDCT/126112002 http://purl.obolibrary.org/obo/CHEBI_6716 A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent. An amphetamine with central nervous system (CNS) stimulating activity. Methamphetamine acts by both facilitating the release of catecholamines, particularly noradrenaline, dopamine and serotonin, from nerve terminals in the brain and by inhibiting their uptake. This leads to an increase in synaptic concentration of these neurotransmitters and results in increased stimulation of postsynaptic receptors. https://en.wikipedia.org/wiki/Category:Methamphetamine https://en.wikipedia.org/wiki/Methamphetamine https://www.wikidata.org/wiki/Q191924 N-methylamphetamine methamphetamine methamphetamines http://id.loc.gov/authorities/subjects/sh85084377 http://purl.obolibrary.org/obo/NCIT_C61840 meth http://purl.bioontology.org/ontology/SNOMEDCT/387499002 http://purl.obolibrary.org/obo/CHEBI_6809 A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer. An orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, enzalutamide inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation and, correspondingly, a reduction in the serum prostate specific antigen (PSA) level. AR over-expression in prostate cancer represents a key mechanism associated with prostate cancer hormone resistance. https://en.wikipedia.org/wiki/Enzalutamide https://www.wikidata.org/wiki/Q1996756 enzalutamide http://purl.obolibrary.org/obo/NCIT_C71744 L02BB04 http://purl.bioontology.org/ontology/SNOMEDCT/703125003 http://purl.obolibrary.org/obo/CHEBI_68534 Any molecule that consists of at least one carbon atom as part of the electrically neutral entity. organic molecule organic molecules http://purl.obolibrary.org/obo/CHEBI_72695 Any organic molecule containing a C#C bond. acetylenic compound acetylenic compounds http://purl.obolibrary.org/obo/CHEBI_73474 A chemical substance that is an organic compound or mixture of compounds that is composed of long-chain molecules and is malleable at ambient temperatures. https://en.wikipedia.org/wiki/Category:Waxes https://en.wikipedia.org/wiki/Wax https://www.wikidata.org/wiki/Q124695 wax waxes http://id.loc.gov/authorities/subjects/sh85145802 QP752.W3 TP669-TP695 http://purl.obolibrary.org/obo/CHEBI_73702 A gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in the treatment of endometriosis and early puberty. It is also used to treat uterine fibroids, to control ovarian stimulation in in vitro fertilization (IVF), and as part of transgender hormone therapy. A potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central precocious puberty and endometriosis. https://en.wikipedia.org/wiki/Nafarelin https://www.wikidata.org/wiki/Q3869873 nafarelin http://purl.obolibrary.org/obo/NCIT_C61613 http://purl.bioontology.org/ontology/MESH/D017274 http://purl.bioontology.org/ontology/SNOMEDCT/109046009 http://purl.obolibrary.org/obo/CHEBI_7445 A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol. The synthetic benzoate ester of estradiol. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. https://en.wikipedia.org/wiki/Estradiol_benzoate https://www.wikidata.org/wiki/Q11450699 17beta-estradiol 3-benzoate 17β-estradiol-3-benzoate estradiol benzoate 17β-estradiol 3-benzoate http://id.loc.gov/authorities/subjects/sh85045007 QP572.E8 http://purl.obolibrary.org/obo/NCIT_C29769 http://purl.bioontology.org/ontology/SNOMEDCT/96349008 http://purl.obolibrary.org/obo/CHEBI_77006 estradiol benzoate EB A steroid which is substituted with one or more chlorine atoms in any position. chlorinated steroid chlorinated steroids http://purl.bioontology.org/ontology/MESH/D013258 http://purl.obolibrary.org/obo/CHEBI_77175 A lactam in which the amide bond is contained within a six-membered ring, which includes the amide nitrogen and the carbonyl carbon. delta-lactam δ-lactam δ-lactams http://purl.obolibrary.org/obo/CHEBI_77727 delta-lactam delta-lactams Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. carbohydrates and carbohydrate derivatives http://purl.obolibrary.org/obo/CHEBI_78616 Any organic molecular entity that contains at least one C=C bond. olefinic compound olefinic compounds http://purl.obolibrary.org/obo/CHEBI_78840 A hormone produced by gonadotropic cells in the anterior pituitary gland. A major gonadotropin secreted by the adenohypophysis (pituitary gland, anterior). Luteinizing hormone regulates steroid production by the interstitial cells of the testis and the ovary. https://en.wikipedia.org/wiki/Luteinizing_hormone https://www.wikidata.org/wiki/Q208360 luteinizing hormone luteinizing hormones http://purl.org/sig/ont/fma/fma74642 LH http://purl.bioontology.org/ontology/MESH/D007986 http://purl.obolibrary.org/obo/CHEBI_81568 Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine. monochlorobenzene monochlorobenzenes http://purl.obolibrary.org/obo/CHEBI_83403 An organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens. (trifluoromethyl)benzene (trifluoromethyl)benzenes http://purl.obolibrary.org/obo/CHEBI_83565 Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent. monofluorobenzene monofluorobenzenes http://purl.obolibrary.org/obo/CHEBI_83575 A 17beta-hydroxy steroid that is testosterone in which the 4-5 double bond has been reduced to a single bond with unspecified configuration at position 5. 17beta-hydroxyandrostan-3-one 17β-hydroxyandrostan-3-one http://purl.obolibrary.org/obo/CHEBI_85278 A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors. receptor modulator receptor modulators http://purl.obolibrary.org/obo/CHEBI_90710 A pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position. An orally bioavailable pyrazolopyrimidinone derivative structurally related to zaprinast, with vasodilating and potential anti-inflammatory activities. Upon oral administration, sildenafil selectively targets and inhibits cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), thereby inhibiting the PDE5-mediated degradation of cGMP found in smooth muscle and increasing cGMP availability. This results in prolonged smooth muscle relaxation in the corpus cavernosum of the penis, thereby causing vasodilation, blood engorgement and a prolonged penile erection. In the smooth muscle of the pulmonary vasculature, the increase in cGMP results in smooth muscle relaxation, vasodilation of the pulmonary vascular bed, relieving pulmonary hypertension and increasing blood flow in the lungs. In addition, sildenafil may reduce airway inflammation and mucus production. https://en.wikipedia.org/wiki/Sildenafil https://www.wikidata.org/wiki/Q191521 sildenafil http://id.loc.gov/authorities/subjects/sh98000937 http://purl.obolibrary.org/obo/NCIT_C61940 http://purl.bioontology.org/ontology/SNOMEDCT/372572000 http://purl.obolibrary.org/obo/CHEBI_9139 A medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It is also used in the treatment of high blood pressure, low blood potassium that does not improve with supplementation, early puberty in boys, acne and excessive hair growth in women, and as a part of feminizing hormone therapy in transgender women. A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7. A synthetic 17-spironolactone corticosteroid with potassium-sparing diuretic, antihypertensive, and antiandrogen activities. Spironolactone competitively inhibits adrenocortical hormone aldosterone activity in the distal renal tubules, myocardium, and vasculature. This agent may inhibit the pathophysiologic effects of aldosterone produced in excess by various types of malignant and benign tumors. https://en.wikipedia.org/wiki/Spironolactone https://www.wikidata.org/wiki/Q422188 spironolactone http://purl.obolibrary.org/obo/NCIT_C840 http://purl.bioontology.org/ontology/MESH/D013148 http://purl.bioontology.org/ontology/SNOMEDCT/387078006 http://purl.obolibrary.org/obo/CHEBI_9241 An eight-carbon ester form of testosterone. The number of ester carbon atoms correlate with the half-life of the prodrug. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels. In addition, this agent promotes the maintenance of male sex characteristics and is indicated for testosterone replacement in hypogonadal males. https://en.wikipedia.org/wiki/Testosterone_cypionate https://www.wikidata.org/wiki/Q27108401 testosterone cypionate http://purl.obolibrary.org/obo/NCIT_C1246 http://purl.bioontology.org/ontology/SNOMEDCT/109034005 http://purl.obolibrary.org/obo/CHEBI_9463 Testosterone enanthate, sold under the brand names Delatestryl and Xyosted among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. It is also used in hormone therapy for transgender men. It is given by injection into muscle usually once every one to four weeks. https://en.wikipedia.org/wiki/Testosterone_enanthate https://www.wikidata.org/wiki/Q27108402 testosterone enanthate http://purl.obolibrary.org/obo/NCIT_C1247 http://purl.bioontology.org/ontology/MESH/C004648 http://purl.bioontology.org/ontology/SNOMEDCT/116071004 http://purl.obolibrary.org/obo/CHEBI_9464 A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). cell in vivo native cell native cells A male germ cell is a germ cell that supports male gamete production. male germ cell male germ cells A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. https://en.wikipedia.org/wiki/Spermatocyte https://www.wikidata.org/wiki/Q3486515 spermatocyte spermatocytes http://purl.org/sig/ont/fma/fma84049 http://purl.obolibrary.org/obo/NCIT_C12605 http://purl.bioontology.org/ontology/MESH/D013090 A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. https://en.wikipedia.org/wiki/Spermatid https://www.wikidata.org/wiki/Q1494188 spermatid spermatids http://purl.org/sig/ont/fma/fma72294 http://purl.obolibrary.org/obo/NCIT_C12604 http://purl.bioontology.org/ontology/MESH/D013087 http://purl.bioontology.org/ontology/SNOMEDCT/38326003 A mature male germ cell that develops from a spermatid. spermatozoon sperm cell sperm cells http://id.loc.gov/authorities/subjects/sh85126546 QL966 QP255 sperm spermatozoon spermatozoa A female germ cell is a germ cell that supports female gamete production. female germ cell female germ cells A female germ cell that has entered meiosis. https://en.wikipedia.org/wiki/Oocyte https://www.wikidata.org/wiki/Q3246226 oocyte oocytes http://purl.org/sig/ont/fma/fma18644 http://purl.obolibrary.org/obo/NCIT_C12598 http://purl.bioontology.org/ontology/MESH/D009865 http://purl.bioontology.org/ontology/SNOMEDCT/86082002 A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. https://en.wikipedia.org/wiki/Egg_cell https://www.wikidata.org/wiki/Q1321695 ovum egg cell egg cells http://id.loc.gov/authorities/subjects/sh85096271 QL965 http://purl.org/sig/ont/fma/fma67343 http://purl.bioontology.org/ontology/MESH/D010063 http://purl.bioontology.org/ontology/SNOMEDCT/263828003 http://purl.bioontology.org/ontology/SNOMEDCT/73153001 ovum ova A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. https://en.wikipedia.org/wiki/Category:Germ_line_cells germ line cell germ line cells A cell with a membrane-bound nucleus. Cells of the higher organisms, containing a true nucleus bounded by a nuclear membrane. https://en.wikipedia.org/wiki/Category:Eukaryotic_cells eukaryotic cell eukaryotic cells http://purl.obolibrary.org/obo/NCIT_C12596 http://purl.bioontology.org/ontology/MESH/D005057 A mature sexual reproductive cell having a single set of unpaired chromosomes. https://en.wikipedia.org/wiki/Gamete https://www.wikidata.org/wiki/Q211050 gamete gametes http://id.loc.gov/authorities/subjects/sh85052973 A mature sexual reproductive cell of the male germline. male gamete male gametes Cells as they occur in animals. https://en.wikipedia.org/wiki/Category:Animal_cells animal cell animal cells The reproductive cell in multicellular organisms. https://en.wikipedia.org/wiki/Category:Germ_cells https://en.wikipedia.org/wiki/Germ_cell https://www.wikidata.org/wiki/Q281579 germ cell germ cells http://id.loc.gov/authorities/subjects/sh85054322 QL964-QL966 http://purl.bioontology.org/ontology/MESH/D005854 A primary oocyte is an oocyte that has not completed female meosis I. primary oocyte primary oocytes http://purl.org/sig/ont/fma/fma18645 http://purl.obolibrary.org/obo/NCIT_C12600 A secondary oocyte is an oocyte that has not completed meiosis II. secondary oocyte secondary oocytes http://purl.org/sig/ont/fma/fma18646 http://purl.obolibrary.org/obo/NCIT_C33523 http://purl.bioontology.org/ontology/SNOMEDCT/46886002 A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. primary spermatocyte primary spermatocytes http://purl.org/sig/ont/fma/fma72292 http://purl.bioontology.org/ontology/SNOMEDCT/49904001 One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. secondary spermatocyte secondary spermatocytes http://purl.org/sig/ont/fma/fma72293 http://purl.bioontology.org/ontology/SNOMEDCT/3374006 A mature sexual reproductive cell of the female germline. female gamete female gametes A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions. https://en.wikipedia.org/wiki/Category:Infectious_diseases https://www.wikidata.org/wiki/Q18123741 communicable disease infectious disease transmissible disease disease by infectious agent diseases by infectious agent http://id.loc.gov/authorities/subjects/sh85029015 RA643-RA644 RC109-RC216 http://purl.obolibrary.org/obo/DOID_0050117 communicable disease communicable diseases infectious disease infectious diseases transmissible disease transmissible diseases A cancer that is classified based on the organ it starts in. cancers by organ system organ system cancer organ system cancers http://purl.obolibrary.org/obo/DOID_0050686 A cancer that is classified by the type of cell from which it is derived. cancers by cell type cell type cancer cell type cancers http://purl.obolibrary.org/obo/DOID_0050687 A large intestine cancer that is located in the terminal part of the large intestine. cancer of anal canal cancer of the anal canal anal canal cancer anal canal cancers http://purl.bioontology.org/ontology/MEDDRA/10002124 http://purl.obolibrary.org/obo/DOID_0050688 A gastrointestinal system cancer that has material basis in epithelial cells. carcinoma of the digestive system digestive system carcinoma carcinoma of the gastrointestinal system gastrointestinal system carcinoma gastrointestinal carcinoma gastrointestinal carcinomas http://purl.obolibrary.org/obo/NCIT_C96963 http://purl.bioontology.org/ontology/MEDDRA/10017940 http://purl.obolibrary.org/obo/HP_0002672 http://purl.obolibrary.org/obo/DOID_0050922 digestive system carcinoma digestive system carcinomas A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol. withdrawal disorder withdrawal disorders http://purl.obolibrary.org/obo/DOID_0060001 A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development. https://www.wikidata.org/wiki/Q3087172 disorder of psychological development developmental disorder of mental health developmental disorders of mental health disorder of psychological development disorders of psychological development A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination. https://en.wikipedia.org/wiki/Specific_developmental_disorder https://www.wikidata.org/wiki/Q7574983 specific developmental disorder, NOS specific developmental disorder specific developmental disorders SDD http://purl.bioontology.org/ontology/SNOMEDCT/10720004 http://purl.obolibrary.org/obo/DOID_0060038 A developmental disorder of mental health that refers to a group of five disorders characterized by impairments in socialization and communication, as well as restricted interests and repetitive behaviors. pervasive developmental disorder, NOS pervasive developmental disorder, unspecified pervasive development disorder pervasive developmental disorder pervasive developmental disorders http://purl.obolibrary.org/obo/NCIT_C97179 PDD F84 http://purl.obolibrary.org/obo/DOID_0060040 pervasive developmental disorder, unspecified unspecified pervasive developmental disorder 299.9 F84.9 pervasive development disorder pervasive development disorders A spectrum of developmental disorders that includes autism, Asperger syndrome, and Rett syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors. Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. autism or autism spectrum disorder autism spectrum disorder, unspecified other specified autism spectrum disorder autism spectrum disorder autism spectrum disorders http://id.loc.gov/authorities/subjects/sh2008009581 http://purl.obolibrary.org/obo/NCIT_C88412 ASD http://purl.bioontology.org/ontology/MEDDRA/10063844 http://purl.bioontology.org/ontology/MESH/D000067877 http://purl.bioontology.org/ontology/SNOMEDCT/35919005 autism spectrum disorder, unspecified autism spectrum disorders, unspecified other specified autism spectrum disorder other specified autism spectrum disorders ASD ASDs A neoplasm that is composed of dysplastic cells and there is no morphologic evidence of infiltration of the surrounding tissues. premalignant neoplasm pre-malignant neoplasm pre-malignant neoplasms http://purl.obolibrary.org/obo/NCIT_C36032 http://purl.obolibrary.org/obo/DOID_0060071 premalignant neoplasm premalignant neoplasms A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites. benign neoplasm benign neoplasms 210-229.99 http://purl.obolibrary.org/obo/NCIT_C3677 http://purl.bioontology.org/ontology/MEDDRA/10060999 D10-D36.9 http://purl.obolibrary.org/obo/DOID_0060072 A disease of anatomical entity that is located in the thoracic cavity. thoracic disease thoracic diseases http://purl.obolibrary.org/obo/DOID_0060118 An agnosia that is a deficiency in understanding, processing, or describing emotions. https://en.wikipedia.org/wiki/Alexithymia https://www.wikidata.org/wiki/Q1129046 alexithymia http://purl.bioontology.org/ontology/MEDDRA/10077719 http://purl.obolibrary.org/obo/HP_0031433 http://purl.bioontology.org/ontology/SNOMEDCT/34413007 http://purl.obolibrary.org/obo/DOID_0060131 A bipolar disorder that is characterized by at least one hypomanic episode and at least one major depressive episode; with this disorder, depressive episodes are more frequent and more intense than manic episodes. https://en.wikipedia.org/wiki/Bipolar_II_disorder https://www.wikidata.org/wiki/Q4086956 bipolar 2 disorder type two bipolar disorder bipolar II disorder BD-II bipolar II http://purl.bioontology.org/ontology/MEDDRA/10004940 F31.81 http://purl.bioontology.org/ontology/SNOMEDCT/83225003 http://purl.obolibrary.org/obo/DOID_0060166 A cell type cancer that has material basis in abnormally proliferating cells derived from precursor cells called blast cells. https://en.wikipedia.org/wiki/Blastoma https://www.wikidata.org/wiki/Q882077 blastoma blastomas http://purl.obolibrary.org/obo/NCIT_C8997 http://purl.obolibrary.org/obo/DOID_0070003 A disorder which is not mental in nature or which is primarily non-mental. https://en.wikipedia.org/wiki/Physical_disorder https://www.wikidata.org/wiki/Q30314000 Differentiating the physical disorders from mental disorders can be a difficult problem in both medicine and law, most notably because it delves into deep issues, and very old and unresolved arguments in philosophy and religion. Many materialists believe that all mental disorders are physical disorders of some kind, even if tests for them have not yet been developed (and it has been the case that some disorders once widely thought to be purely mental, are known to have physical origins, such as schizophrenia). Some recognized physical disorders produce significant behavioral changes. For example, fever, head trauma, and hyperthyroidism can produce delirium. physical disorder physical disorders http://purl.obolibrary.org/obo/DOID_0080015 A gastrointestinal system cancer that is located in the intestine. intestinal cancer intestinal cancers http://purl.obolibrary.org/obo/DOID_10155 A reproductive cancer that is located in the prostate. https://en.wikipedia.org/wiki/Category:Prostate_cancer https://en.wikipedia.org/wiki/Prostate_cancer https://www.wikidata.org/wiki/Q181257 prostate cancer prostate cancers http://id.loc.gov/authorities/subjects/sh85107606 RC280.P7 http://purl.bioontology.org/ontology/MEDDRA/10060862 http://purl.obolibrary.org/obo/HP_0012125 http://purl.obolibrary.org/obo/DOID_10283 A disease by infectious agent that results in infection, has material basis in bacteria. https://en.wikipedia.org/wiki/Category:Bacterial_diseases https://www.wikidata.org/wiki/Q727028 bacterial infectious disease, NOS bacterial infectious disease bacterial infectious diseases http://id.loc.gov/authorities/subjects/sh85010843 QR201.B34 RC115-RC116 bacterial disease http://purl.bioontology.org/ontology/SNOMEDCT/87628006 bacterial disease bacterial diseases A personality disorder that involves a need for social isolation, anxiety in social situations, odd behavior and thinking, and often unconventional beliefs. https://en.wikipedia.org/wiki/Schizotypal_personality_disorder https://www.wikidata.org/wiki/Q861560 schizotypal disorder schizotypal personality disorder 301.22 http://purl.obolibrary.org/obo/NCIT_C92632 STPD StPD http://purl.bioontology.org/ontology/MEDDRA/10039651 F21 http://purl.bioontology.org/ontology/MESH/D012569 http://purl.bioontology.org/ontology/SNOMEDCT/31027006 http://purl.obolibrary.org/obo/DOID_10646 An anxiety disorder that involves the feeling of excessive and inappropriate levels of anxiety over being separated from a person to whom the individual has a strong emotional attachment or place. https://en.wikipedia.org/wiki/Separation_anxiety_disorder https://www.wikidata.org/wiki/Q2300749 separation anxiety disorder of childhood separation anxiety disorder separation anxiety disorders 309.21 http://purl.obolibrary.org/obo/NCIT_C35014 SAD http://purl.bioontology.org/ontology/MEDDRA/10040045 http://purl.obolibrary.org/obo/DOID_10685 A personality disorder that involves a prolonged disturbance of personality function characterized by depth and variability of moods. https://en.wikipedia.org/wiki/Borderline_personality_disorder https://en.wikipedia.org/wiki/Category:Borderline_personality_disorder https://www.wikidata.org/wiki/Q208166 borderline personality disorder 301.83 http://purl.obolibrary.org/obo/NCIT_C92633 BPD http://purl.bioontology.org/ontology/MEDDRA/10006034 F60.3 http://purl.bioontology.org/ontology/MESH/D001883 http://purl.bioontology.org/ontology/SNOMEDCT/20010003 http://purl.obolibrary.org/obo/DOID_10930 A personality disorder that is characterized by a pervasive psychological dependence on other people. https://en.wikipedia.org/wiki/Dependent_personality_disorder https://www.wikidata.org/wiki/Q320719 dependent personality disorder 301.6 http://purl.obolibrary.org/obo/NCIT_C92637 DPD http://purl.bioontology.org/ontology/MEDDRA/10012355 F60.7 http://purl.bioontology.org/ontology/MESH/D003859 http://purl.bioontology.org/ontology/SNOMEDCT/84466009 http://purl.obolibrary.org/obo/DOID_10931 A personality disorder that is characterized by a pervasive pattern of preoccupation with orderliness, perfectionism, and mental and interpersonal control at the expense of flexibility, openness, and efficiency. https://en.wikipedia.org/wiki/Obsessive%E2%80%93compulsive_personality_disorder https://www.wikidata.org/wiki/Q231578 obsessive–compulsive personality disorder obsessive-compulsive personality disorder 301.4 http://purl.obolibrary.org/obo/NCIT_C92638 OCPD http://purl.bioontology.org/ontology/MEDDRA/10029901 F60.5 http://purl.bioontology.org/ontology/SNOMEDCT/1376001 http://purl.obolibrary.org/obo/DOID_10932 An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension. An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions). https://en.wikipedia.org/wiki/Category:Obsessive%E2%80%93compulsive_disorder https://en.wikipedia.org/wiki/Obsessive%E2%80%93compulsive_disorder https://www.wikidata.org/wiki/Q178190 obsessive compulsive disorder obsessive–compulsive disorder obsessive-compulsive disorder obsessive-compulsive disorders http://id.loc.gov/authorities/subjects/sh85093751 RC533 http://purl.obolibrary.org/obo/NCIT_C88411 OCD http://purl.bioontology.org/ontology/MEDDRA/10029898 http://purl.bioontology.org/ontology/MESH/D009771 http://purl.bioontology.org/ontology/SNOMEDCT/191736004 http://purl.obolibrary.org/obo/DOID_10933 A disorder of mental health in which the normally well-integrated functions of memory, identity, perception, or consciousness are separated (dissociated). https://en.wikipedia.org/wiki/Category:Dissociative_disorders https://en.wikipedia.org/wiki/Dissociative_disorder https://www.wikidata.org/wiki/Q2627467 dissociative disorder dissociative disorders http://id.loc.gov/authorities/subjects/sh92004916 RC553.D5 http://purl.obolibrary.org/obo/NCIT_C92197 DD http://purl.bioontology.org/ontology/MEDDRA/10013462 http://purl.bioontology.org/ontology/MESH/D004213 http://purl.bioontology.org/ontology/SNOMEDCT/44376007 http://purl.obolibrary.org/obo/DOID_10935 DD DDs A personality disorder that is characterized by a lack of interest in social relationships, a tendency towards a solitary lifestyle, secretiveness, emotional coldness and sometimes sexual apathy, with a simultaneous rich, elaborate and exclusively internal fantasy world. https://en.wikipedia.org/wiki/Schizoid_personality_disorder https://www.wikidata.org/wiki/Q498237 schizoid personality disorder 301.2 http://purl.obolibrary.org/obo/NCIT_C92631 SPD SzPD http://purl.bioontology.org/ontology/MEDDRA/10039624 F60.1 http://purl.bioontology.org/ontology/MESH/D012557 http://purl.bioontology.org/ontology/SNOMEDCT/52954000 http://purl.obolibrary.org/obo/DOID_10936 A personality disorder that is characterized by paranoia and a pervasive, long-standing suspiciousness and generalized mistrust of others. https://en.wikipedia.org/wiki/Paranoid_personality_disorder https://www.wikidata.org/wiki/Q747735 paranoid personality disorder 301.0 http://purl.obolibrary.org/obo/NCIT_C92630 PPD http://purl.bioontology.org/ontology/MEDDRA/10033869 F60.0 http://purl.bioontology.org/ontology/MESH/D010260 http://purl.bioontology.org/ontology/SNOMEDCT/13601005 http://purl.obolibrary.org/obo/DOID_10938 A personality disorder that involves a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. https://en.wikipedia.org/wiki/Antisocial_personality_disorder https://www.wikidata.org/wiki/Q118418 dissocial personality disorder antisocial personality disorder 301.7 http://purl.obolibrary.org/obo/NCIT_C88413 APD ASPD http://purl.bioontology.org/ontology/MEDDRA/10002822 F60.2 http://purl.bioontology.org/ontology/MESH/D000987 http://purl.bioontology.org/ontology/SNOMEDCT/26665006 http://purl.obolibrary.org/obo/DOID_10939 dissocial personality disorder DPD http://purl.bioontology.org/ontology/MEDDRA/10013455 F60.2 A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). At least some of the symptoms must be present before the age of 7 years. attention deficit-hyperactivity disorder attention deficit/hyperactivity disorder attention deficit hyperactivity disorder, NOS attention deficit hyperactivity disorder, other specified presentation attention deficit hyperactivity disorder, presentation unspecified attention deficit disorder with hyperactivity attention deficit hyperactivity disorder attention deficit hyperactivity disorders http://purl.obolibrary.org/obo/NCIT_C97160 ADHD http://purl.bioontology.org/ontology/MEDDRA/10003736 http://purl.bioontology.org/ontology/MEDDRA/10064104 http://purl.obolibrary.org/obo/HP_0007018 F90 http://purl.bioontology.org/ontology/SNOMEDCT/406506008 http://purl.obolibrary.org/obo/DOID_1094 attention deficit hyperactivity disorder, other specified presentation attention deficit hyperactivity disorders, other specified presentation attention deficit hyperactivity disorder, presentation unspecified attention deficit hyperactivity disorders, presentation unspecified attention deficit disorder with hyperactivity 314.01 ADDH http://purl.bioontology.org/ontology/MESH/D001289 A disease involving the ovary or ovaries. https://en.wikipedia.org/wiki/Ovarian_disease https://www.wikidata.org/wiki/Q7113244 disease of ovary disease of the ovaries ovarian disease ovarian diseases http://purl.obolibrary.org/obo/DOID_1100 disease of ovary disease of ovary, NOS diseases of ovary disease of the ovaries diseases of the ovaries A cell type cancer that has material basis in abnormally proliferating cells derived from embryonic mesoderm. sarcoma sarcomas http://id.loc.gov/authorities/subjects/sh85117504 http://purl.bioontology.org/ontology/SNOMEDCT/372151005 http://purl.obolibrary.org/obo/DOID_1115 Anxiety disorder characterized by the persistent and irrational fear, anxiety, or avoidance of social or performance situations. social anxiety disorder social phobia social phobias 300.23 http://purl.bioontology.org/ontology/MEDDRA/10041250 F40.1 http://purl.bioontology.org/ontology/MESH/D000072861 http://purl.bioontology.org/ontology/SNOMEDCT/25501002 http://purl.obolibrary.org/obo/DOID_11257 social anxiety disorder https://en.wikipedia.org/wiki/Social_anxiety_disorder social anxiety disorders http://purl.obolibrary.org/obo/NCIT_C34927 SAD http://purl.bioontology.org/ontology/MEDDRA/10041242 A disease involving the vagina. https://en.wikipedia.org/wiki/Vaginal_disease https://www.wikidata.org/wiki/Q18211693 disease of vagina, NOS disease of the vagina vaginal disease vaginal diseases http://purl.obolibrary.org/obo/DOID_121 disease of the vagina diseases of the vagina A psychological disorder characterized by an appetite for substances that are largely non-nutritive. An appetite for and the persistent ingestion of non-food substances such as clay. In order to diagnose pica, this behavior must have persisted over a period of at least one month. An eating disorder that is characterized by an appetite for non-nutritive substances or food ingredients. https://en.wikipedia.org/wiki/Category:Pica_(disorder) https://en.wikipedia.org/wiki/Pica_(disorder) https://www.wikidata.org/wiki/Q1134891 pica disease pica picas http://id.loc.gov/authorities/subjects/sh85101913 307.52 http://purl.obolibrary.org/obo/HP_0011856 http://purl.bioontology.org/ontology/MESH/D010842 http://purl.obolibrary.org/obo/DOID_12128 An eating disorder characterized by the restraining of food intake for a period of time followed by an over intake or binging period that results in feelings of guilt and low self-esteem. An eating disorder that is characterized by a cycle of binge eating (bulimia or bingeing) followed by inappropriate acts (purging) to avert weight gain. Purging methods often include self-induced vomiting, use of laxatives or diuretics, excessive exercise, and fasting. https://en.wikipedia.org/wiki/Bulimia_nervosa https://www.wikidata.org/wiki/Q69268828 Although bulimia nervosa is often simply referred to as "bulimia", "bulimia" refers to bulimic behavior and not the disorder itself. bulimia nervosa 307.51 http://purl.obolibrary.org/obo/NCIT_C34440 BN bulimia http://purl.bioontology.org/ontology/MEDDRA/10006550 F50.2 http://purl.bioontology.org/ontology/MESH/D052018 http://purl.bioontology.org/ontology/SNOMEDCT/78004001 http://purl.obolibrary.org/obo/DOID_12129 A mood disorder that involves the presence of a low mood almost daily over a span of at least two years. Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. dysthymic disorder dysthymic disorders 300.4 http://purl.obolibrary.org/obo/NCIT_C34562 F34.1 http://purl.bioontology.org/ontology/MESH/D019263 http://purl.obolibrary.org/obo/DOID_12139 A developmental disorder characterized by difficulties with social interaction and communication, and by restricted and repetitive behavior. autistic disorder http://purl.bioontology.org/ontology/MEDDRA/10003808 http://purl.bioontology.org/ontology/SNOMEDCT/408856003 http://purl.obolibrary.org/obo/DOID_12849 A central nervous system disease that results in the progressive deterioration of function or structure of neurons. neurodegenerative disease neurodegenerative diseases http://purl.obolibrary.org/obo/DOID_1289 A disorder characterized by sexual hypoactivity. https://en.wikipedia.org/wiki/Hypoactive_sexual_desire_disorder https://www.wikidata.org/wiki/Q303555 female hypoactive sexual desire disorder male hypoactive sexual desire disorder hypoactive sexual desire disorder HSDD F52.0 302.71 http://purl.obolibrary.org/obo/DOID_13868 A disease by infectious agent that is carried out by a parasite which by definition is a pathogen that simultaneously injures and derives sustenance from its host. parasitic infectious disease parasitic infectious diseases parasitic disease http://purl.obolibrary.org/obo/DOID_1398 parasitic disease parasitic diseases http://purl.bioontology.org/ontology/MESH/D010272 A bipolar disorder that is characterized by at least one manic or mixed episode. https://en.wikipedia.org/wiki/Bipolar_I_disorder https://www.wikidata.org/wiki/Q4915474 bipolar 1 disorder type one bipolar disorder bipolar I disorder BD-I bipolar I http://purl.bioontology.org/ontology/MEDDRA/10004939 http://purl.bioontology.org/ontology/SNOMEDCT/371596008 http://purl.obolibrary.org/obo/DOID_14042 A large intestine cancer that is located in the anus. https://en.wikipedia.org/wiki/Anal_cancer https://www.wikidata.org/wiki/Q484827 anus cancer cancer of the anus anal cancer anal cancers http://purl.bioontology.org/ontology/MEDDRA/10061424 http://purl.obolibrary.org/obo/DOID_14110 anus cancer anus cancers Any of various diseases affecting the ureters. ureteral disease ureteral diseases http://purl.obolibrary.org/obo/DOID_1426 An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation. https://en.wikipedia.org/wiki/Generalized_anxiety_disorder https://www.wikidata.org/wiki/Q845224 generalized anxiety disorder generalized anxiety disorders 300.02 http://purl.obolibrary.org/obo/NCIT_C92622 GAD http://purl.bioontology.org/ontology/MEDDRA/10018105 F41.1 http://purl.bioontology.org/ontology/SNOMEDCT/21897009 http://purl.obolibrary.org/obo/DOID_14320 A disease that is characterized by abnormally rapid cell division. https://www.wikidata.org/wiki/Q18554796 neoplastic disease disease of cellular proliferation diseases of cellular proliferation http://purl.obolibrary.org/obo/DOID_14566 neoplastic disease neoplastic diseases A disease of anatomical entity that is located in reproductive system organs. https://en.wikipedia.org/wiki/Reproductive_system_disease https://www.wikidata.org/wiki/Q7314317 reproductive system disease reproductive system diseases http://purl.obolibrary.org/obo/DOID_15 A personality disorder that is characterized by a pervasive pattern of social inhibition, feelings of inadequacy, extreme sensitivity to negative evaluation, and avoidance of social interaction. https://en.wikipedia.org/wiki/Avoidant_personality_disorder https://www.wikidata.org/wiki/Q509122 avoidant personality disorder 301.82 http://purl.obolibrary.org/obo/NCIT_C92636 AvPD http://purl.bioontology.org/ontology/MEDDRA/10003865 F60.6 http://purl.bioontology.org/ontology/SNOMEDCT/37746008 http://purl.obolibrary.org/obo/DOID_1509 A disorder of mental health that involve long-term patterns of thoughts and behaviors that cause serious problems with relationships and work. personality disorders and disturbances in behavior https://en.wikipedia.org/wiki/Personality_disorder https://www.wikidata.org/wiki/Q270673 character disorder personality disorder personality disorders http://purl.obolibrary.org/obo/NCIT_C34922 PD http://purl.bioontology.org/ontology/MEDDRA/10034721 http://purl.obolibrary.org/obo/HP_0012075 http://purl.bioontology.org/ontology/SNOMEDCT/33449004 http://purl.obolibrary.org/obo/DOID_1510 personality disorders and disturbances in behavior http://purl.bioontology.org/ontology/MEDDRA/10034726 character disorder character disorders PD PDs A disease involving the penis. https://www.wikidata.org/wiki/Q18554834 disease of the penis penile disease penile diseases http://purl.obolibrary.org/obo/DOID_1529 disease of the penis diseases of the penis A disorder of mental health that affects cognitive functions including memory processing, perception and problem solving. cognitive disorder cognitive disorders http://purl.obolibrary.org/obo/NCIT_C92196 http://purl.bioontology.org/ontology/MEDDRA/10057668 http://purl.bioontology.org/ontology/SNOMEDCT/443265004 http://purl.obolibrary.org/obo/DOID_1561 A disease by infectious agent that results in infection, has material basis in fungi, which pass the resistance barriers of the human or animal body. https://en.wikipedia.org/wiki/Category:Fungal_diseases https://www.wikidata.org/wiki/Q464067 mycosis fungal infectious disease fungal infectious diseases http://purl.bioontology.org/ontology/MEDDRA/10067330 http://purl.bioontology.org/ontology/SNOMEDCT/3218000 http://purl.obolibrary.org/obo/DOID_1564 mycosis mycoses A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. A substance use disorder that involves the recurring use of alcoholic beverages despite negative consequences. alcoholism dipsomania https://en.wikipedia.org/wiki/Alcoholism https://www.wikidata.org/wiki/Q15326 alcohol use disorder alcohol use disorders http://id.loc.gov/authorities/subjects/sh85003292 HV5001-HV5720.5 RC564.7-RC565.9 AUD http://purl.bioontology.org/ontology/MEDDRA/10001639 http://purl.bioontology.org/ontology/MEDDRA/10080021 http://purl.obolibrary.org/obo/HP_0030955 http://purl.bioontology.org/ontology/MESH/D000437 http://purl.bioontology.org/ontology/SNOMEDCT/7200002 http://purl.obolibrary.org/obo/DOID_1574 dipsomania https://en.wikipedia.org/wiki/Dipsomania https://www.wikidata.org/wiki/Q2717096 http://purl.bioontology.org/ontology/MEDDRA/10013037 A thoracic cancer that originates in the mammary gland. https://en.wikipedia.org/wiki/Breast_cancer https://en.wikipedia.org/wiki/Category:Breast_cancer https://www.wikidata.org/wiki/Q128581 breast cancer breast cancers http://id.loc.gov/authorities/subjects/sh85016679 RC280.B8 http://purl.bioontology.org/ontology/MEDDRA/10006187 http://purl.obolibrary.org/obo/DOID_1612 A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis. https://en.wikipedia.org/wiki/Cancer https://en.wikipedia.org/wiki/Category:Cancer https://www.wikidata.org/wiki/Q12078 cancer cancers http://id.loc.gov/authorities/subjects/sh85019492 RC261-RC282 http://purl.bioontology.org/ontology/MEDDRA/10007050 http://purl.obolibrary.org/obo/DOID_162 A disease of anatomical entity that occurs in the muscular and/or skeletal system. musculoskeletal system disease musculoskeletal system diseases musculoskeletal disease http://purl.obolibrary.org/obo/DOID_17 musculoskeletal disease musculoskeletal diseases A disorder of mental health where symptoms are deliberately produced, feigned or exaggerated in order to falsely demonstrate the presence of an illness. https://en.wikipedia.org/wiki/Category:Factitious_disorders https://en.wikipedia.org/wiki/Factitious_disorder https://www.wikidata.org/wiki/Q2686385 factitious disorder with predominantly psychological signs and symptoms Note that authorities disagree about whether factitious disorder is a somatoform disorder. factitious disorder http://purl.obolibrary.org/obo/NCIT_C92198 http://purl.bioontology.org/ontology/MEDDRA/10061595 http://purl.bioontology.org/ontology/MESH/D005162 http://purl.bioontology.org/ontology/SNOMEDCT/50705009 http://purl.obolibrary.org/obo/DOID_1766 factitious disorder with predominantly psychological signs and symptoms 300.16 A disorder whose predominant feature is a loss or alteration in physical functioning that suggests a physical disorder but that is actually a direct expression of a psychological conflict or need. A somatoform disorder that involves numbness, blindness, paralysis or fits without a neurological cause. https://en.wikipedia.org/wiki/Conversion_disorder https://www.wikidata.org/wiki/Q1051355 conversion disorder conversion disorders 300.11 http://purl.bioontology.org/ontology/MEDDRA/10010893 http://purl.bioontology.org/ontology/MESH/D003291 http://purl.obolibrary.org/obo/DOID_1768 A disease of anatomical entity that is located in kidney, ureter, bladder and urethra. https://www.wikidata.org/wiki/Q7900883 renal system disease urinary system disease urinary system diseases http://purl.obolibrary.org/obo/DOID_18 renal system disease renal disease A cell type cancer that has material basis in abnormally proliferating cells derived from melanocytes which are found in skin, the bowel and the eye. The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea). A malignant skin tumor of originating from melanocytes, pigment cells normally present in the epidermis and sometimes in the dermis. https://en.wikipedia.org/wiki/Category:Melanoma https://en.wikipedia.org/wiki/Melanoma https://www.wikidata.org/wiki/Q180614 malignant melanoma melanoma melanomas http://id.loc.gov/authorities/subjects/sh85083381 RC280.M37 http://purl.obolibrary.org/obo/NCIT_C3224 http://purl.bioontology.org/ontology/MEDDRA/10053571 http://purl.obolibrary.org/obo/HP_0002861 http://purl.bioontology.org/ontology/MESH/D008545 http://purl.obolibrary.org/obo/DOID_1909 malignant melanoma malignant melanomas An organ system cancer that is manifested in the reproductive organs. reproductive organ cancer reproductive cancer reproductive cancers http://purl.obolibrary.org/obo/DOID_193 reproductive organ cancer reproductive organ cancers A disease involving the fallopian tube. https://www.wikidata.org/wiki/Q18554947 disease of the fallopian tubes fallopian tube disease fallopian tube diseases http://purl.obolibrary.org/obo/DOID_1962 disease of the fallopian tubes diseases of the fallopian tubes A colorectal cancer that is located in the rectum. cancer of rectum cancer of the rectum rectum cancer rectal cancer rectal cancers http://purl.bioontology.org/ontology/MEDDRA/10038038 http://purl.obolibrary.org/obo/DOID_1993 rectum cancer rectum cancers A cognitive disorder that involves an excessive, irrational dread of everyday situations. anxiety disorder/anxiety state anxiety or fear-related disorders anxiety, dissociative and somatoform disorders https://en.wikipedia.org/wiki/Anxiety_disorder https://en.wikipedia.org/wiki/Category:Anxiety_disorders https://www.wikidata.org/wiki/Q544006 anxiety disorder, unspecified other anxiety disorder other specified anxiety disorder anxiety disorder anxiety disorders http://id.loc.gov/authorities/subjects/sh2005006293 RC531 http://purl.obolibrary.org/obo/NCIT_C2878 http://purl.bioontology.org/ontology/MEDDRA/10057666 http://purl.bioontology.org/ontology/SNOMEDCT/197480006 http://purl.obolibrary.org/obo/DOID_2030 anxiety, dissociative and somatoform disorders 300 anxiety disorder, unspecified F41.9 other anxiety disorder other anxiety disorders F41 other specified anxiety disorder other specified anxiety disorders F41.8 A disorder characterized by an individual's inability to comprehend or share ideas or feelings because of an impairment in language, speech, or hearing. A specific developmental disorder that involves specific developmental disorders of speech and language. https://en.wikipedia.org/wiki/Category:Communication_disorders https://en.wikipedia.org/wiki/Communication_disorder https://www.wikidata.org/wiki/Q1058691 communications disorder communication disorder communication disorders http://purl.obolibrary.org/obo/NCIT_C2958 http://purl.bioontology.org/ontology/MEDDRA/10061046 http://purl.bioontology.org/ontology/SNOMEDCT/278919001 http://purl.obolibrary.org/obo/DOID_2033 communications disorder communications disorders A disease involving the vulva. https://en.wikipedia.org/wiki/Vulvar_disease https://www.wikidata.org/wiki/Q18211751 disease of vulva, NOS disease of the vulva disease of vulva vulvar disease vulvar diseases http://purl.obolibrary.org/obo/DOID_2059 disease of the vulva diseases of the vulva disease of vulva diseases of vulva A large intestine cancer that is located in the colon. cancer of colon cancer of the colon colon cancer colonic cancer colonic cancers http://purl.bioontology.org/ontology/MEDDRA/10009944 http://purl.bioontology.org/ontology/MEDDRA/10009989 http://purl.obolibrary.org/obo/HP_0003003 http://purl.obolibrary.org/obo/DOID_219 colon cancer colon cancers A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes. https://www.wikidata.org/wiki/Q5442760 Note that the disease/organ system does not have gender, but is rather simply present in a reproductive system that delivers female gametes. female reproductive system disease female reproductive system diseases http://purl.obolibrary.org/obo/DOID_229 A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. https://en.wikipedia.org/wiki/Category:Multiple_sclerosis https://en.wikipedia.org/wiki/Multiple_sclerosis https://www.wikidata.org/wiki/Q8277 sclerosis multiple multiple sclerosis 340 http://purl.obolibrary.org/obo/NCIT_C3243 MS http://purl.bioontology.org/ontology/MEDDRA/10039720 G35 http://purl.bioontology.org/ontology/MESH/D009103 http://purl.bioontology.org/ontology/SNOMEDCT/24700007 http://purl.obolibrary.org/obo/DOID_2377 A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality. psychotic disorder psychotic disorders http://purl.bioontology.org/ontology/MEDDRA/10061920 http://purl.bioontology.org/ontology/MESH/D011618 http://purl.bioontology.org/ontology/SNOMEDCT/69322001 http://purl.obolibrary.org/obo/DOID_2468 A syndrome resulting from bilateral lesions of the medial temporal lobe (including amygdaloid nucleus). Klüver–Bucy syndrome may present with compulsive eating, hypersexuality, insertion of inappropriate objects in the mouth (hyperorality), visual agnosia, and docility. https://en.wikipedia.org/wiki/Kl%C3%BCver%E2%80%93Bucy_syndrome temporal lobectomy behavior syndrome Kluver-Bucy syndrome Kluver–Bucy syndrome Klver-Bucy syndrome Klüver–Bucy syndrome 310.0 http://purl.obolibrary.org/obo/NCIT_C84802 http://purl.bioontology.org/ontology/MEDDRA/10066431 http://purl.bioontology.org/ontology/MESH/D020232 http://purl.obolibrary.org/obo/DOID_2510 A disease involving the testis. https://www.wikidata.org/wiki/Q7705854 disease of testis, NOS other testicular disease disease of testis disease of the testicles testicular disease testicular diseases http://purl.obolibrary.org/obo/DOID_2519 other testicular disease other testicular diseases disease of testis diseases of testis disease of the testicles diseases of the testicles A personality disorder that involves an excessive preoccupation with issues of personal adequacy, power, prestige and vanity. https://en.wikipedia.org/wiki/Narcissistic_personality_disorder https://www.wikidata.org/wiki/Q1060310 narcissistic personality disorder 301.81 http://purl.obolibrary.org/obo/NCIT_C92635 NPD http://purl.bioontology.org/ontology/MEDDRA/10028712 F60.81 http://purl.bioontology.org/ontology/SNOMEDCT/80711002 http://purl.obolibrary.org/obo/DOID_2745 A parasitic infectious disease that is caused by parasitic protozoa which are microorganisms classified as unicellular eukaryotes. protozoal disease parasitic protozoa infectious disease parasitic protozoa infectious diseases http://purl.obolibrary.org/obo/DOID_2789 protozoal disease protozoal diseases B50-B64 A disease of anatomical entity that is located in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body. endocrine, nutritional and metabolic diseases endocrine, nutritional and metabolic diseases, and immunity disorders https://en.wikipedia.org/wiki/Category:Endocrine_diseases https://www.wikidata.org/wiki/Q2661443 disease of other endocrine glands endocrine system disease endocrine system diseases endocrine, nutritional and metabolic diseases E00-E89 endocrine, nutritional and metabolic diseases, and immunity disorders 240-279.99 disease of other endocrine glands diseases of other endocrine glands 249-259.99 A cell type cancer that has material basis in abnormally proliferating cells derived from epithelial cells. https://en.wikipedia.org/wiki/Carcinoma https://en.wikipedia.org/wiki/Category:Carcinoma https://www.wikidata.org/wiki/Q33525 carcinoma carcinomas http://purl.obolibrary.org/obo/NCIT_C2916 http://purl.bioontology.org/ontology/MEDDRA/10007284 http://purl.bioontology.org/ontology/MESH/D002277 http://purl.bioontology.org/ontology/SNOMEDCT/68453008 http://purl.obolibrary.org/obo/DOID_305 An organ system cancer located in the gastrointestinal tract that is manifested in organs of the gastrointestinal system. https://en.wikipedia.org/wiki/Category:Gastrointestinal_cancer https://en.wikipedia.org/wiki/Gastrointestinal_cancer https://www.wikidata.org/wiki/Q5526839 cancer of digestive system digestive system cancer cancer of gastrointestinal system cancer of gastrointestinal tract gastrointestinal system cancer gastrointestinal tract cancer gastrointestinal cancer gastrointestinal cancers GI cancer http://purl.obolibrary.org/obo/DOID_3119 digestive system cancer digestive system cancers gastrointestinal system cancer gastrointestinal system cancers gastrointestinal tract cancer gastrointestinal tract cancers GI cancer GI cancers Any disease of the nervous system in which the myelin sheath of neurons is damaged. https://en.wikipedia.org/wiki/Demyelinating_disease https://www.wikidata.org/wiki/Q1186703 demyelinating disease of central nervous system demyelinating disease demyelinating diseases http://purl.obolibrary.org/obo/DOID_3213 demyelinating disease of central nervous system https://en.wikipedia.org/wiki/Category:Demyelinating_diseases_of_CNS demyelinating diseases of CNS demyelinating disease of CNS demyelinating diseases of central nervous system A cell type benign neoplasm that is composed of a mixture of gonadal elements. A complex neoplasm composed of a mixture of gonadal elements, such as large primordial germ cells, immature Sertoli cells or granulosa cells of the sex cord, and gonadal stromal cells. Gonadoblastomas are most often associated with gonadal dysgenesis, 46, XY. https://en.wikipedia.org/wiki/Gonadoblastoma https://www.wikidata.org/wiki/Q5581320 gonadoblastoma gonadoblastomas http://purl.obolibrary.org/obo/NCIT_C3754 http://purl.bioontology.org/ontology/MEDDRA/10018506 http://purl.obolibrary.org/obo/HP_0000150 http://purl.bioontology.org/ontology/MESH/D018238 http://purl.bioontology.org/ontology/SNOMEDCT/74751003 http://purl.obolibrary.org/obo/DOID_3301 A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system. CNS disease disease of central nervous system central nervous system disease central nervous system diseases http://purl.obolibrary.org/obo/DOID_331 CNS disease CNS diseases disease of central nervous system diseases of central nervous system diseases of the central nervous system A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. A mood disorder that involves alternating periods of mania and depression. http://purl.obolibrary.org/obo/NBO_0000258 manic depression https://en.wikipedia.org/wiki/Bipolar_disorder https://en.wikipedia.org/wiki/Category:Bipolar_disorder https://www.wikidata.org/wiki/Q131755 bipolar disorder not otherwise specified bipolar disorder, unspecified bipolar affective disorder bipolar disorder bipolar disorders http://purl.obolibrary.org/obo/NCIT_C34423 BD BPD http://purl.bioontology.org/ontology/MEDDRA/10057667 http://purl.obolibrary.org/obo/HP_0007302 F31 http://purl.bioontology.org/ontology/MESH/D001714 http://purl.bioontology.org/ontology/SNOMEDCT/13746004 http://purl.obolibrary.org/obo/DOID_3312 bipolar disorder not otherwise specified https://en.wikipedia.org/wiki/Bipolar_disorder_not_otherwise_specified https://www.wikidata.org/wiki/Q3540858 BD-NOS bipolar disorder, unspecified 296.80 bipolar affective disorder bipolar affective disorders A cognitive disorder a disturbance in which the person's mood is hypothesized to be the main underlying feature. A cognitive disorder that involves an excessive, irrational dread of everyday situations. affective disorder https://en.wikipedia.org/wiki/Category:Mood_disorders https://en.wikipedia.org/wiki/Mood_disorder https://www.wikidata.org/wiki/Q188638 mood affective disorder The term given for a group of diagnoses in the DSM-IV-TR classification system where a disturbance in the person's emotional mood is hypothesised to be the main underlying feature. The classification is known as mood (affective) disorders in ICD-10. mood disorder mood disorders http://purl.obolibrary.org/obo/NCIT_C92200 http://purl.bioontology.org/ontology/MEDDRA/10079614 http://purl.bioontology.org/ontology/MESH/D019964 http://purl.bioontology.org/ontology/SNOMEDCT/46206005 http://purl.obolibrary.org/obo/DOID_3324 affective disorder affective disorders http://id.loc.gov/authorities/subjects/sh85001494 RC537-RC545 mood affective disorder mood affective disorders A personality disorder that is characterized by a pattern of excessive emotionality and attention-seeking, including an excessive need for approval and inappropriately seductive behavior, usually beginning in early adulthood. https://en.wikipedia.org/wiki/Category:Histrionic_personality_disorder https://en.wikipedia.org/wiki/Histrionic_personality_disorder https://www.wikidata.org/wiki/Q845787 histrionic personality disorder 301.5 http://purl.obolibrary.org/obo/NCIT_C92634 http://purl.bioontology.org/ontology/MEDDRA/10020155 F60.4 http://purl.bioontology.org/ontology/MESH/D006677 http://purl.bioontology.org/ontology/SNOMEDCT/55341008 http://purl.obolibrary.org/obo/DOID_334 A disease involving the uterus. https://www.wikidata.org/wiki/Q18555940 disease of uterus, NOS disease of the uterus uterine disease uterine diseases http://purl.obolibrary.org/obo/DOID_345 disease of the uterus diseases of the uterus A breast cancer that has material basis in abnormally proliferating cells derived from epithelial cells. carcinoma of breast carcinoma of the breast breast carcinoma breast carcinomas http://purl.obolibrary.org/obo/NCIT_C4872 http://purl.bioontology.org/ontology/MEDDRA/10006204 http://purl.obolibrary.org/obo/DOID_3459 Any of various diseases affecting the bladder. bladder disease bladder diseases http://purl.obolibrary.org/obo/DOID_365 A rare malignant mesenchymal neoplasm that arises from the prostate gland. prostatic sarcoma sarcoma of prostate sarcoma of the prostate prostate sarcoma http://purl.obolibrary.org/obo/NCIT_C7731 http://purl.obolibrary.org/obo/DOID_4054 prostatic sarcoma sarcoma, prostatic A communication disorder that is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss. https://en.wikipedia.org/wiki/Agnosia https://en.wikipedia.org/wiki/Category:Agnosia https://www.wikidata.org/wiki/Q220322 agnosia agnosias http://purl.obolibrary.org/obo/NCIT_C84542 http://purl.bioontology.org/ontology/MEDDRA/10048663 http://purl.obolibrary.org/obo/HP_0010524 R48.1 http://purl.bioontology.org/ontology/MESH/D000377 http://purl.bioontology.org/ontology/SNOMEDCT/42341009 http://purl.obolibrary.org/obo/DOID_4090 A primary bacterial infectious disease that is a sexually transmitted systemic disease, has material basis in Treponema pallidum subsp pallidum, which is transmitted by sexual contact, transmitted by blood product transfusion, transmitted by congenital method from mother to fetus or transmitted by contact with infectious lesions. If left untreated, produces chancres, rashes, and systemic lesions in a clinical course with three stages continued over many years. https://en.wikipedia.org/wiki/Category:Syphilis https://en.wikipedia.org/wiki/Syphilis https://www.wikidata.org/wiki/Q41083 syphilis http://id.loc.gov/authorities/subjects/sh85131679 RC201-RC201.9 http://purl.obolibrary.org/obo/NCIT_C35055 http://purl.bioontology.org/ontology/MEDDRA/10062120 http://purl.bioontology.org/ontology/MESH/D013587 http://purl.bioontology.org/ontology/SNOMEDCT/76272004 http://purl.obolibrary.org/obo/DOID_4166 A speech disorder that involves a complete inability to speak. https://en.wikipedia.org/wiki/Muteness https://www.wikidata.org/wiki/Q671776 muteness mutism http://purl.bioontology.org/ontology/MEDDRA/10028403 http://purl.obolibrary.org/obo/HP_0002300 http://purl.bioontology.org/ontology/SNOMEDCT/88052002 http://purl.obolibrary.org/obo/DOID_4189 A category of psychiatric disorders which are characterized by the presence of physical symptoms that suggest a medical condition but are not fully explained by any known medical reasons. A disease of mental health that involves physical symptoms suggesting a physical illness where the biological or medical cause of the symptoms is indeterminate. Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by another medical condition, by the direct effects of a substance, or by another mental disorder. The medically unexplained symptoms must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. somatic symptom and related disorders https://en.wikipedia.org/wiki/Somatic_symptom_disorder https://www.wikidata.org/wiki/Q936549 other somatoform disorder somatoform disorder not otherwise specified somatoform disorder, unspecified undifferentiated somatoform disorder psychosomatic disorder somatic symptom disorder somato-psychic disorder somatoform disorder somatoform disorders http://id.loc.gov/authorities/subjects/sh85124779 RC552.S66 300.8 http://purl.obolibrary.org/obo/NCIT_C34956 http://purl.bioontology.org/ontology/MEDDRA/10054153 http://purl.bioontology.org/ontology/MEDDRA/10078076 F45 http://purl.bioontology.org/ontology/MESH/D013001 http://purl.bioontology.org/ontology/SNOMEDCT/31297008 http://purl.obolibrary.org/obo/DOID_4737 other somatoform disorder other somatoform disorders 300.89 somatoform disorder, unspecified F45.9 undifferentiated somatoform disorder 300.82 psychosomatic disorder psychosomatic disorders somatic symptom disorder somatic symptom disorders somato-psychic disorder somato-psychic disorders A reproductive system disease that affects male reproductive organs. https://www.wikidata.org/wiki/Q6742925 Note that the disease/organ system does not have gender, but is rather simply present in a reproductive system that delivers male gametes. male reproductive system disease male reproductive system diseases http://purl.obolibrary.org/obo/DOID_48 A anus cancer that has material basis in abnormally proliferating cells derived from epithelial cells and is located in the anus. anus carcinoma carcinoma of anus carcinoma of the anus anal carcinoma anal carcinomas http://purl.obolibrary.org/obo/NCIT_C9291 http://purl.bioontology.org/ontology/MEDDRA/10002141 http://purl.bioontology.org/ontology/SNOMEDCT/448315008 http://purl.obolibrary.org/obo/DOID_4908 An organ system cancer located_in the thoracic cavity that develops in the different types of cells within the lungs, as well as less common cancers of the esophagus, the trachea, or the chest wall. thorax cancer thoracic cancer thoracic cancers http://purl.obolibrary.org/obo/DOID_5093 thorax cancer thorax cancers A disorder of mental health that involves disruption of sleep patterns. sleep disorders and disturbances sleep wake disorder https://en.wikipedia.org/wiki/Category:Sleep_disorders https://en.wikipedia.org/wiki/Sleep_disorder https://www.wikidata.org/wiki/Q177190 disorder sleep non-organic sleep disorder sleep disorder, unspecified somnipathy disorder of sleep sleep disorder sleep disorders http://id.loc.gov/authorities/subjects/sh85123404 RC547-RC549 http://purl.obolibrary.org/obo/NCIT_C3376 http://purl.bioontology.org/ontology/MEDDRA/10013268 http://purl.bioontology.org/ontology/SNOMEDCT/39898005 http://purl.obolibrary.org/obo/DOID_535 sleep disorders and disturbances http://purl.bioontology.org/ontology/MEDDRA/10040991 sleep wake disorder sleep wake disorders http://purl.bioontology.org/ontology/MESH/D012893 non-organic sleep disorder non-organic sleep disorders sleep disorder, unspecified 307.46 G47.9 somnipathy somnipathies disorder of sleep disorders of sleep Any of various diseases affecting the kidney. kidney disease kidney diseases http://purl.obolibrary.org/obo/DOID_557 An intestinal cancer that effects the long, tube-like organ that is connected to the small intestine at one end and the anus at the other. large intestine cancer large intestinal cancer large intestinal cancers http://purl.obolibrary.org/obo/DOID_5672 large intestine cancer large intestine cancers An anxiety disorder where fear and anxiety are triggered by a specific stimulus or situation. other phobic anxiety disorder phobic anxiety disorder, unspecified phobic anxiety disorder psychological phobia phobic disorder phobic disorders 300.2 http://purl.bioontology.org/ontology/MEDDRA/10034919 http://purl.bioontology.org/ontology/MESH/D010698 http://purl.bioontology.org/ontology/SNOMEDCT/386810004 http://purl.obolibrary.org/obo/DOID_591 other phobic anxiety disorder other phobic anxiety disorders F40.8 phobic anxiety disorder, unspecified F40.9 phobic anxiety disorder phobic anxiety disorders F40 psychological phobia psychological phobias A phobic disorder involving the specific anxiety about being in a place or situation where escape is difficult or embarrassing or where help may be unavailable. https://en.wikipedia.org/wiki/Agoraphobia https://en.wikipedia.org/wiki/Category:Agoraphobia agoraphobia with panic disorder agoraphobia without panic disorder agoraphobia http://purl.obolibrary.org/obo/NCIT_C34362 http://purl.bioontology.org/ontology/MEDDRA/10001502 http://purl.obolibrary.org/obo/HP_0000756 F40.0 http://purl.bioontology.org/ontology/MESH/D000379 http://purl.bioontology.org/ontology/SNOMEDCT/70691001 http://purl.obolibrary.org/obo/DOID_593 agoraphobia with panic disorder 300.21 agoraphobia without panic disorder agoraphobia without mention of panic attacks 300.22 A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait. An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress. https://en.wikipedia.org/wiki/Panic_disorder https://www.wikidata.org/wiki/Q741713 panic disorder panic disorders http://purl.obolibrary.org/obo/NCIT_C34890 http://purl.bioontology.org/ontology/MEDDRA/10033666 http://purl.bioontology.org/ontology/MESH/D016584 http://purl.bioontology.org/ontology/SNOMEDCT/371631005 http://purl.obolibrary.org/obo/DOID_594 A phobic disorder that is characterized by an unreasonable or irrational fear related to exposure to specific objects or situations. https://en.wikipedia.org/wiki/Specific_phobia other isolated or specific phobias isolated phobia simple phobia specific phobia specific phobias http://purl.obolibrary.org/obo/NCIT_C35284 http://purl.bioontology.org/ontology/MEDDRA/10041446 F40.2 http://purl.bioontology.org/ontology/MESH/C562465 http://purl.obolibrary.org/obo/DOID_599 other isolated or specific phobias 300.29 isolated phobia isolated phobias simple phobia simple phobias An anal canal cancer that derives from epithelial cells. carcinoma of anal canal carcinoma of the anal canal anal canal carcinoma anal canal carcinomas http://purl.obolibrary.org/obo/NCIT_C7489 http://purl.bioontology.org/ontology/MESH/C563020 http://purl.bioontology.org/ontology/SNOMEDCT/285310000 http://purl.obolibrary.org/obo/DOID_6126 A disease that disrupts the functioning of an anatomical entity. disease by anatomical system disease of anatomical entity diseases of anatomical entities http://purl.obolibrary.org/obo/DOID_7 Any of various diseases affecting the urethra. urethral disease urethral diseases http://purl.obolibrary.org/obo/DOID_732 A psychotic disorder that involves an uncommon psychiatric condition in which patients present with circumscribed symptoms of non-bizarre delusions, but with the absence of prominent hallucinations and no thought disorder, mood disorder, or significant flattening effect. paranoid disorder https://en.wikipedia.org/wiki/Category:Delusional_disorders https://en.wikipedia.org/wiki/Delusional_disorder https://www.wikidata.org/wiki/Q721073 delusional disorder delusional disorders 297.1 http://purl.obolibrary.org/obo/NCIT_C94379 F22.0 http://purl.bioontology.org/ontology/SNOMEDCT/48500005 http://purl.obolibrary.org/obo/DOID_778 paranoid disorder paranoid disorders A disease of anatomical entity that is located in the central nervous system or located in the peripheral nervous system. https://en.wikipedia.org/wiki/Nervous_system_disease https://www.wikidata.org/wiki/Q6996973 nervous system disease A connective tissue cancer that derives from lymphatic endothelium, and derives from spindle cells, results in formation of vascular channels that fill with blood cells, has material basis in Human herpesvirus 8 (HHV8). A systemic disease which can present with cutaneous lesions with or without internal involvement. Tumors are caused by Human herpesvirus 8 (HHV8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). Kaposi's sarcoma NOS unspecified Kaposi's sarcoma Kaposi sarcoma Kaposi's sarcoma Kaposi's sarcomas http://homosaurus.org/v2/kaposisSarcoma 176 KS http://purl.bioontology.org/ontology/MEDDRA/10023284 http://purl.bioontology.org/ontology/MEDDRA/10023285 http://purl.obolibrary.org/obo/HP_0100726 C46 http://purl.obolibrary.org/obo/DOID_8632 Kaposi's sarcoma NOS http://purl.bioontology.org/ontology/MEDDRA/10023290 unspecified Kaposi's sarcoma Kaposi's sarcoma, unspecified Kaposi's sarcoma of unspecified site Kaposi's sarcoma, unspecified site 176.9 http://purl.bioontology.org/ontology/MEDDRA/10023298 C46.9 http://homosaurus.org/v2/kaposisSarcoma A specific developmental disorder that is characterized by abnormal eating habits that may involve either insufficient or excessive food intake to the detriment of an individual's physical and emotional health. feeding and eating disorders https://en.wikipedia.org/wiki/Category:Eating_disorders https://en.wikipedia.org/wiki/Eating_disorder https://www.wikidata.org/wiki/Q373822 eating disorder, unspecified disordered eating disorder of eating eating disorder eating disorders http://id.loc.gov/authorities/subjects/sh86004209 RC552.E18 http://purl.obolibrary.org/obo/NCIT_C89332 ED http://purl.bioontology.org/ontology/MEDDRA/10014062 http://purl.bioontology.org/ontology/SNOMEDCT/72366004 http://purl.obolibrary.org/obo/DOID_8670 feeding and eating disorders eating and feeding disorders http://purl.bioontology.org/ontology/MESH/D001068 eating disorder, unspecified http://purl.bioontology.org/ontology/MEDDRA/10014066 F50.9 disordered eating Abnormal eating behaviors, including binge eating, compulsive eating, emotional eating, night eating, and self-induced vomiting, though not at a level that rises to the diagnosis of eating disorder. http://purl.obolibrary.org/obo/NCIT_C121669 disorder of eating disorders of eating An eating disorder characterized by refusal to maintain a healthy body weight, and an obsessive fear of gaining weight due to a distorted self image. An eating disorder that is characterized by the lack or loss of appetite, known as anorexia. Other features include excess fear of becoming overweight; body image disturbance; significant weight loss; refusal to maintain minimal normal weight; and amenorrhea. https://en.wikipedia.org/wiki/Anorexia_nervosa https://en.wikipedia.org/wiki/Category:Anorexia_nervosa https://www.wikidata.org/wiki/Q131749 Although anorexia nervosa is often simply referred to as "anorexia", "anorexia" refers to anorexia behavior and not the disorder itself. anorexia nervosa 307.1 http://purl.obolibrary.org/obo/NCIT_C34387 AN anorexia http://purl.bioontology.org/ontology/MEDDRA/10002649 F50.0 http://purl.bioontology.org/ontology/MESH/D000856 http://purl.bioontology.org/ontology/SNOMEDCT/56882008 http://purl.obolibrary.org/obo/DOID_8689 A herpes simplex that results in infection located in genital system, or located in rectum, has material basis in Human herpesvirus 1 or has material basis in Human herpesvirus 2, which is transmitted by sexual contact. The infection has symptom sores, has symptom fever, and has symptom swollen glands. https://en.wikipedia.org/wiki/Genital_herpes https://www.wikidata.org/wiki/Q7476596 genital herpes A communication disorder that involves difficulty with the act of speech production. speech disorder speech disorders http://purl.obolibrary.org/obo/DOID_92 A large intestine cancer that is located in the colon and/or located in the rectum. https://en.wikipedia.org/wiki/Category:Colorectal_cancer https://en.wikipedia.org/wiki/Colorectal_cancer https://www.wikidata.org/wiki/Q188874 colon/rectal cancer colorectal cancer colorectal cancers CRC http://purl.bioontology.org/ontology/MEDDRA/10061451 http://purl.obolibrary.org/obo/DOID_9256 colon/rectal cancer colon/rectal cancers A disease by infectious agent that results in infection, has material basis in viruses. https://en.wikipedia.org/wiki/Category:Viral_diseases https://en.wikipedia.org/wiki/Viral_disease https://www.wikidata.org/wiki/Q1928978 virus disease viral infectious disease viral infectious diseases http://id.loc.gov/authorities/subjects/sh2002006451 http://id.loc.gov/authorities/subjects/sh85143818 574.234 RA644.V55 RC114.5-RC114.6 viral disease http://purl.bioontology.org/ontology/SNOMEDCT/34014006 http://purl.obolibrary.org/obo/DOID_934 virus disease virus diseases 574.234 20 viral disease viral diseases Features of the Earth, typically those that were created naturally. https://en.wikipedia.org/wiki/Geographical_feature geographical feature geographic feature geographic features http://purl.obolibrary.org/obo/ENVO_00000000 geographical feature geographical features An anthropogenic geographic feature is a geographic feature resulting from the influence of human beings on nature. An anthropogenic geographic feature is a geographic feature resulting from the influence of human beings on nature. artificial geographic feature manmade feature anthropogenic geographic feature anthropogenic geographic features http://purl.obolibrary.org/obo/ENVO_00000002 artificial geographic feature artificial geographic features manmade feature man-made feature man-made features manmade features A construction which enables the movement of humans, their animals or their vehicles. transport feature transport features http://purl.obolibrary.org/obo/ENVO_00000010 A marine water body which is constitutes the majority of an astronomical body's hydrosphere. ocean oceans http://id.loc.gov/authorities/subjects/sh85093871 A large expanse of saline water usually connected with an ocean. https://en.wikipedia.org/wiki/Category:Seas https://www.wikidata.org/wiki/Q165 sea seas http://id.loc.gov/authorities/subjects/sh2003003080 http://purl.bioontology.org/ontology/SNOMEDCT/225742004 An accumulation of water of varying size. https://en.wikipedia.org/wiki/Body_of_water https://en.wikipedia.org/wiki/Category:Bodies_of_water https://www.wikidata.org/wiki/Q15324 waterbody body of water water body water bodies http://id.loc.gov/authorities/subjects/sh2003004821 waterbody waterbodies body of water bodies of water An open way for the passage of vehicles, persons, or animals on land. https://en.wikipedia.org/wiki/Category:Roads https://en.wikipedia.org/wiki/Road https://www.wikidata.org/wiki/Q34442 road roads http://purl.obolibrary.org/obo/ENVO_00000064 http://purl.bioontology.org/ontology/SNOMEDCT/272510001 A feature that has been constructed by deliberate human effort. construction constructions http://purl.obolibrary.org/obo/ENVO_00000070 A permanent walled and roofed construction. A structure that has a roof and walls and stands more or less permanently in one place. buildings and structures https://en.wikipedia.org/wiki/Building building buildings http://purl.obolibrary.org/obo/ENVO_00000073 http://purl.obolibrary.org/obo/NCIT_C80231 buildings and structures https://en.wikipedia.org/wiki/Category:Buildings_and_structures A landform consisting of loose rock particles such as sand, gravel, shingle, pebbles, cobble, or even shell fragments along the shoreline of a body of water. beach beaches http://purl.obolibrary.org/obo/ENVO_00000091 A part of an astronomical body which is primarily composed of a continuous volume of solid material, shaped by one or more environmental processes. geological feature physiographic feature solid astronomical body part solid astronomical body parts http://purl.obolibrary.org/obo/ENVO_00000191 geological feature geological features physiographic feature physiographic features A sea that is not connected with an ocean. landlocked sea landlocked seas A building in which a business presents a selection of goods and offers to trade or sell them to customers for money or other goods. store shop shops http://purl.obolibrary.org/obo/ENVO_00002221 http://purl.bioontology.org/ontology/SNOMEDCT/257701001 store stores A building part is a construction which is part of a building. building part building parts http://purl.obolibrary.org/obo/ENVO_01000420 A bathroom is a room which contains a washbasin or other fixture, such as a shower or bath, used for bathing by humans. https://en.wikipedia.org/wiki/Bathroom https://en.wikipedia.org/wiki/Category:Bathrooms https://www.wikidata.org/wiki/Q190771 bathroom bathrooms http://purl.obolibrary.org/obo/ENVO_01000422 http://purl.bioontology.org/ontology/SNOMEDCT/223359008 A building part which is separated from other building parts by one or more interior walls and, optionally, outdoor areas by one or more exterior walls. https://en.wikipedia.org/wiki/Category:Rooms https://en.wikipedia.org/wiki/Room https://www.wikidata.org/wiki/Q180516 room rooms http://purl.obolibrary.org/obo/ENVO_01000426 http://purl.obolibrary.org/obo/NCIT_C69074 A piece of furniture with a raised surface commonly used to seat a single person. A seat, typically for one person, that has a back and legs. http://purl.obolibrary.org/obo/ENVO_01000586 https://en.wikipedia.org/wiki/Category:Chairs https://en.wikipedia.org/wiki/Chair https://www.wikidata.org/wiki/Q15026 chair chairs http://id.loc.gov/authorities/subjects/sh85022351 NK2715 TS886.5.C45 TT197.5.C45 http://purl.obolibrary.org/obo/NCIT_C122026 http://purl.bioontology.org/ontology/SNOMEDCT/706699008 A piece of furniture is a movable object intended to support various human activities such as seating (e.g., chairs, stools and sofas) and sleeping (e.g., beds). http://purl.obolibrary.org/obo/ENVO_01000587 piece of furniture pieces of furniture A mass of water water mass water masses A building which is publically accessible. public building public buildings http://purl.obolibrary.org/obo/ENVO_01000781 http://purl.obolibrary.org/obo/NCIT_C53546 http://purl.bioontology.org/ontology/SNOMEDCT/257674002 A material part of an astronomical body. astronomical body part astronomical body parts http://purl.obolibrary.org/obo/ENVO_01000813 A building within which food and drink are prepared and served to customers in exchange for money or other goods and/or services. https://en.wikipedia.org/wiki/Category:Restaurants https://en.wikipedia.org/wiki/Restaurant restaurant restaurants http://purl.obolibrary.org/obo/ENVO_01000934 http://id.loc.gov/authorities/subjects/sh85113249 TX945-TX945.5 http://purl.bioontology.org/ontology/SNOMEDCT/257689006 A building which is primarily used to facilitate the buying or selling of goods or services.