VICO merged.owl
type: Ontology
creator: Yongqun "Oliver" He (YH)
creator: Jie Zheng (JZ)
creator: Asiyah Yu Lin (YL)
description: The vaccination informed consent Ontology (VICO) is an ontology in the domain of vaccination/immunization informed consent.
date: 2016-01-30
version info: Arbor version; 1.0.52
license: http://creativecommons.org/licenses/by/3.0/

BFO OWL specification label
type: AnnotationProperty
editor preferred term: BFO OWL specification label
curator notes: Really of interest to developers only
definition: Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification.
sub property of: label

BFO CLIF specification label
type: AnnotationProperty
definition source: Person:Alan Ruttenberg
editor preferred term: BFO CLIF specification label
curator notes: Really of interest to developers only
definition: Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2
sub property of: label

editor preferred term
type: AnnotationProperty
label: editor preferred term~editor preferred label
label: editor preferred label
editor preferred term: editor preferred term~editor preferred label
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
definition: The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)
editor preferred term: editor preferred term
has curation status: ready for release

example of usage
type: AnnotationProperty
definition: A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
editor preferred term: example
editor preferred term: example of usage
has curation status: ready for release

has curation status
type: AnnotationProperty
definition source: OBI_0000281
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Bill Bug
term editor: PERSON:Melanie Courtot
editor preferred term: has curation status

definition
type: AnnotationProperty
label: textual definition
editor preferred term: definition
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
definition: The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
has curation status: ready for release

editor note
type: AnnotationProperty
is metadata tag: 1
database_cross_reference: IAO:0000116
id: editor_note
shorthand: editor_note
has_obo_namespace: uberon
definition: An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
definition source: GROUP:OBI:<http://purl.obfoundry.org/obo/obi>
term editor: PERSON:Daniel Schober
editor preferred term: editor note
has curation status: ready for release

term editor
type: AnnotationProperty
label: definition editor
editor note: 20110707, MC: label update to term editor and definition modified accordingly. See http://code.google.com/p/information-artifact-ontology/issues/detail?id=115.
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
definition: Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people
definition: Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people
term editor: PERSON:Daniel Schober
editor preferred term: definition editor
editor preferred term: term editor
has curation status: ready for release

alternative term
type: AnnotationProperty
definition: An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
editor preferred term: alternative term
has curation status: pending final vetting

definition source
type: AnnotationProperty
definition source: Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Daniel Schober
editor preferred term: definition source
definition: formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007
has curation status: ready for release

curator notes
type: AnnotationProperty
label: curator note
is metadata tag: 1
database_cross_reference: IAO:0000232
id: curator_notes
shorthand: curator_notes
has_obo_namespace: uberon
definition: An administrative note of use for a curator but of no use for a user
term editor: PERSON:Alan Ruttenberg
editor preferred term: curator note
has curation status: ready for release

imported from
type: AnnotationProperty
definition: For external terms/classes, the ontology from which the term was imported
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Melanie Courtot
editor preferred term: imported from
has curation status: pending final vetting

elucidation
type: AnnotationProperty
definition source: Person:Barry Smith
elucidation: Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms
editor preferred term: elucidation
term editor: person:Alan Ruttenberg

has associated axiom(nl)
type: AnnotationProperty
elucidation: An axiom associated with a term expressed using natural language
definition source: Person:Alan Ruttenberg
term editor: Person:Alan Ruttenberg
editor preferred term: has associated axiom(nl)

has associated axiom(fol)
type: AnnotationProperty
elucidation: An axiom expressed in first order logic using CLIF syntax
definition source: Person:Alan Ruttenberg
term editor: Person:Alan Ruttenberg
editor preferred term: has associated axiom(fol)

term_mapping_to_UMLS
type: AnnotationProperty
sub property of: seeAlso

term_mapping_to_NCIT
type: AnnotationProperty
sub property of: seeAlso

term_mapping_to_HL7v3
type: AnnotationProperty
sub property of: seeAlso

has_specified_input
type: AnnotationProperty
editor note: 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works.
term editor: PERSON: Bjoern Peters
term editor: PERSON: Larry Hunter
term editor: PERSON: Melanie Coutot
editor preferred term: has_specified_input
definition: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
term editor: PERSON: Alan Ruttenberg
example of usage: see is_input_of example_of_usage
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl
type: ObjectProperty
sub property of: has participant
domain: planned process
inverse of: is_specified_input_of

has_specified_output
type: AnnotationProperty
term editor: PERSON: Bjoern Peters
term editor: PERSON: Larry Hunter
term editor: PERSON: Melanie Courtot
editor preferred term: has_specified_output
definition: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
term editor: PERSON: Alan Ruttenberg
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl
type: ObjectProperty
sub property of: has participant
domain: planned process
inverse of: is_specified_output_of

ISA alternative term
type: AnnotationProperty
definition source: ISA tools project (http://isa-tools.org)
term editor: Person: Philippe Rocca-Serra
editor preferred term: ISA alternative term
term editor: Person: Alejandra Gonzalez-Beltran
definition: An alternative term used by the ISA tools project (http://isa-tools.org).
sub property of: alternative term
has curation status: ready for release

organism NCBITaxon ID
type: AnnotationProperty
definition: The NCBITaxon ontology ID of an organism.
term editor: Oliver He, Yue Liu

temporal interpretation
type: AnnotationProperty
definition: An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.
editor preferred term: temporal interpretation
sub property of: logical macro assertion on an object property

logical macro assertion
type: AnnotationProperty
definition: An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.

logical macro assertion on a property
type: AnnotationProperty
definition: A logical macro assertion whose domain is an IRI for a property
sub property of: logical macro assertion

logical macro assertion on an object property
type: AnnotationProperty
sub property of: logical macro assertion on a property

has_rank
type: AnnotationProperty
definition: A metadata relation between a class and its taxonomic rank (eg species, family)
has_obo_namespace: ncbi_taxonomy

eco subset
type: AnnotationProperty
sub property of: subset_property

Creator
type: AnnotationProperty
label: creator

Source
type: AnnotationProperty

subset_property
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

has_broad_synonym
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

in_subset
type: AnnotationProperty

shorthand
type: AnnotationProperty

label
type: AnnotationProperty

part of
type: ObjectProperty
type: TransitiveProperty
editor note: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
editor note: Parthood as a relation between instances: The primitive instance-level relation p part_of p1 is illustrated in assertions such as: this instance of rhodopsin mediated phototransduction part_of this instance of visual perception. This relation satisfies at least the following standard axioms of mereology: reflexivity (for all p, p part_of p); anti-symmetry (for all p, p1, if p part_of p1 and p1 part_of p then p and p1 are identical); and transitivity (for all p, p1, p2, if p part_of p1 and p1 part_of p2, then p part_of p2). Analogous axioms hold also for parthood as a relation between spatial regions. For parthood as a relation between continuants, these axioms need to be modified to take account of the incorporation of a temporal argument. Thus for example the axiom of transitivity for continuants will assert that if c part_of c1 at t and c1 part_of c2 at t, then also c part_of c2 at t. Parthood as a relation between classes: To define part_of as a relation between classes we again need to distinguish the two cases of continuants and processes, even though the explicit reference to instants of time now falls away. For continuants, we have C part_of C1 if and only if any instance of C at any time is an instance-level part of some instance of C1 at that time, as for example in: cell nucleus part_ of cell.
Source: http://www.obofoundry.org/ro/#OBO_REL:part_of
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
definition: a core relation that holds between a part and its whole
example of usage: my brain is part of my body (continuant parthood, two material entities)
example of usage: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
editor preferred term: part of
alternative term: part_of
example of usage: this day is part of this year (occurrent parthood)
imported from: BFO
inverse of: has part
temporal interpretation: axiom holds for all times
imported from: ico.owl
imported from: obi.owl
imported from: ro.owl
imported from: vo.owl

has part
type: ObjectProperty
type: TransitiveProperty
editor note: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
definition: a core relation that holds between a whole and its part
editor preferred term: has part
alternative term: has_part
example of usage: my body has part my brain (continuant parthood, two material entities)
example of usage: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
example of usage: this year has part this day (occurrent parthood)
imported from: BFO
temporal interpretation: axiom holds for all times
imported from: ico.owl
imported from: obi.owl
imported from: ogg.owl
imported from: ro.owl
imported from: vo.owl

inheres in at all times
type: ObjectProperty
BFO CLIF specification label: inheresInAt
editor note: BFO2 Reference: independent continuant that is not a spatial region
BFO OWL specification label: inheres-in_at
editor note: BFO2 Reference: specifically dependent continuant
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'inheres in at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'inheres in@en(x,y,t)'.
has associated axiom(fol): (iff (inheresInAt a b t) (and (DependentContinuant a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [051-002]
editor note: BFO 2 Reference: Inherence is a subrelation of s-depends_on which holds between a dependent continuant and an independent continuant that is not a spatial region. Since dependent continuants cannot migrate from one independent continuant bearer to another, it follows that if b s-depends_on independent continuant c at some time, then b s-depends_on c at all times at which a exists. Inherence is in this sense redundantly time-indexed.For example, consider the particular instance of openness inhering in my mouth at t as I prepare to take a bite out of a donut, followed by a closedness at t+1 when I bite the donut and start chewing. The openness instance is then shortlived, and to say that it s-depends_on my mouth at all times at which this openness exists, means: at all times during this short life. Every time you make a fist, you make a new (instance of the universal) fist. (Every time your hand has the fist-shaped quality, there is created a new instance of the universal fist-shaped quality.)
definition: b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002])
domain: specifically dependent continuant
sub property of: specifically depends on at all times
imported from: ogg.owl
imported from: vo.owl
range: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region

bearer of at some time
type: ObjectProperty
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'bearer of at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'bearer of@en'(x,y,t)
editor note: BFO2 Reference: independent continuant that is not a spatial region
BFO CLIF specification label: bearerOfAt
has associated axiom(fol): (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004]
definition: b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])
BFO OWL specification label: bearer-of_st
editor note: BFO2 Reference: specifically dependent continuant
range: specifically dependent continuant
sub property of: has specific dependent at some time
imported from: vo.owl
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region

realized in
type: ObjectProperty
elucidation: [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process
has associated axiom(fol): (forall (x y z t) (if (and (RealizableEntity x) (Process y) (realizesAt y x t) (bearerOfAt z x t)) (hasParticipantAt y z t))) // axiom label in BFO2 CLIF: [106-002]
BFO CLIF specification label: realizedIn
BFO OWL specification label: realized-in
has associated axiom(nl): if a realizable entity b is realized in a process p, then p stands in the has_participant relation to the bearer of b. (axiom label in BFO2 Reference: [106-002])
alternative term: is realized by
editor preferred term: realized in
alternative term: realized_in
example of usage: this disease is realized in this disease course
example of usage: this fragility is realized in this shattering
example of usage: this investigator role is realized in this investigation
range: process
domain: realizable entity
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl

realizes
type: ObjectProperty
BFO CLIF specification label: realizes
comment: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process
BFO OWL specification label: realizes
has associated axiom(fol): (forall (x y t) (if (realizesAt x y t) (and (Process x) (or (Disposition y) (Role y)) (exists (z) (and (MaterialEntity z) (hasParticipantAt x z t) (bearerOfAt z y t)))))) // axiom label in BFO2 CLIF: [059-003]
editor preferred term: realizes
example of usage: this disease course realizes this disease
example of usage: this investigation realizes this investigator role
example of usage: this shattering realizes this fragility
elucidation: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
domain: process
range: realizable entity
inverse of: realized in
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl

participates_in
type: ObjectProperty
label: participates in
label: participates in at some time
BFO OWL specification label: participates-in_st
editor note: [copied from inverse property 'has participant at some time'] BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant
editor note: [copied from inverse property 'has participant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has participant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has participant@en'(x,y,t)
editor note: [copied from inverse property 'has participant at some time'] BFO2 Reference: process
BFO CLIF specification label: participatesInAt
editor note: [copied from inverse property 'has participant at some time'] BFO 2 Reference: Spatial regions do not participate in processes.
elucidation: [copied from inverse property 'has participant at some time'] has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])
alternative term: participates_in
range: process
imported from: obi.owl
imported from: vo.owl
domain: Class
  intersection of: continuant
  intersection of: Class
    complement of: spatial region

has participant
type: ObjectProperty
label: has participant at some time
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001]
BFO CLIF specification label: hasParticipantAt
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001]
editor note: BFO2 Reference: process
BFO OWL specification label: has-participant_st
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003]
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has participant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has participant@en'(x,y,t)
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
editor note: BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant
alternative term: has_participant
elucidation: has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])
has associated axiom(nl): if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003])
has associated axiom(nl): if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003])
has associated axiom(nl): if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001])
has associated axiom(nl): if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001])
has associated axiom(nl): if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001])
domain: process
inverse of: participates_in
imported from: obi.owl
imported from: vo.owl
property chain axiom: realizes
property chain axiom: inheres in at all times
range: Class
  intersection of: continuant
  intersection of: Class
    complement of: spatial region

concretized by at some time
type: ObjectProperty
example of usage: [copied from inverse property 'concretizes at some time'] You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head.
BFO OWL specification label: concretized-by_st
example of usage: [copied from inverse property 'concretizes at some time'] You may concretize a piece of software by installing it in your computer
elucidation: [copied from inverse property 'concretizes at some time'] b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])
example of usage: [copied from inverse property 'concretizes at some time'] you may concretize a poem as a pattern of memory traces in your head
editor note: [copied from inverse property 'concretizes at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t)
range: specifically dependent continuant
domain: generically dependent continuant
imported from: ogg.owl
imported from: vo.owl

concretizes at some time
type: ObjectProperty
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t)
BFO OWL specification label: concretizes_st
has associated axiom(fol): (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001]
BFO CLIF specification label: concretizesAt
has associated axiom(fol): (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002]
example of usage: You may concretize a piece of software by installing it in your computer
example of usage: You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head.
elucidation: b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])
has associated axiom(nl): if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001])
example of usage: you may concretize a poem as a pattern of memory traces in your head
domain: specifically dependent continuant
range: generically dependent continuant
inverse of: concretized by at some time
imported from: vo.owl

preceded_by
type: ObjectProperty
type: TransitiveProperty
label: preceded by

specifically depends on at all times
type: ObjectProperty
has associated axiom(fol): (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]
editor note: BFO2 Reference: specifically dependent continuant\; process; process boundary
BFO OWL specification label: s-depends-on_at
has associated axiom(fol): (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
has associated axiom(fol): (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
example of usage: A pain s-depends_on the organism that is experiencing the pain
editor note: BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
has associated axiom(nl): If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
example of usage: a gait s-depends_on the walking object. (All at some specific time.)
has associated axiom(nl): if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
BFO CLIF specification label: specificallyDependsOn
has associated axiom(fol): (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'specifically depends on at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'specifically depends on@en(x,y,t)'.
has associated axiom(fol): (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
editor note: BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
has associated axiom(nl): If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has associated axiom(nl): If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
elucidation: To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64
example of usage: a shape s-depends_on the shaped object
has associated axiom(nl): an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
example of usage: one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
example of usage: the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: the two-sided reciprocal s-dependence of the roles of husband and wife [20
sub property of: specifically depends on at some time
imported from: ogg.owl
imported from: vo.owl

located in at all times
type: ObjectProperty
type: TransitiveProperty
BFO CLIF specification label: locatedInAt
editor note: BFO2 Reference: independent continuant
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001]
has associated axiom(fol): (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001]
BFO OWL specification label: located-in_at
has associated axiom(fol): (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001]
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001]
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'located in at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'located in@en(x,y,t)'.
has associated axiom(nl): Located_in is transitive. (axiom label in BFO2 Reference: [046-001])
example of usage: Mary located_in Salzburg
definition: b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001])
example of usage: the Empire State Building located_in New York.
example of usage: this portion of cocaine located_in this portion of blood
example of usage: this stem cell located_in this portion of bone marrow
example of usage: your arm located_in your body
sub property of: located in at some time
imported from: vo.owl

occupies spatial region at some time
type: ObjectProperty
BFO OWL specification label: located-at-r_st
has associated axiom(fol): (forall (x y r_1 t) (if (and (occupiesSpatialRegionAt x r_1 t) (continuantPartOfAt y x t)) (exists (r_2) (and (continuantPartOfAt r_2 r_1 t) (occupiesSpatialRegionAt y r_2 t))))) // axiom label in BFO2 CLIF: [043-001]
editor note: BFO2 Reference: independent continuant
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t)
has associated axiom(fol): (forall (x r t) (if (occupiesSpatialRegionAt x r t) (and (SpatialRegion r) (IndependentContinuant x)))) // axiom label in BFO2 CLIF: [041-002]
editor note: BFO2 Reference: spatial region
has associated axiom(fol): (forall (r t) (if (Region r) (occupiesSpatialRegionAt r r t))) // axiom label in BFO2 CLIF: [042-002]
elucidation: b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002])
has associated axiom(nl): every region r is occupies_spatial_region r at all times. (axiom label in BFO2 Reference: [042-002])
has associated axiom(nl): if b occupies_spatial_region r at t & b continuant_part_of b at t, then there is some r which is continuant_part_of r at t such that b occupies_spatial_region r at t. (axiom label in BFO2 Reference: [043-001])
BFO CLIF specification label: occupiesSpatialRegionAt
domain: independent continuant
range: spatial region
inverse of: has spatial occupant at some time
imported from: ogg.owl
imported from: vo.owl

has function at some time
type: ObjectProperty
BFO OWL specification label: has-f_st
has associated axiom(fol): (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001]
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has function at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has function@en'(x,y,t)
definition: a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001])
BFO CLIF specification label: hasFunctionAt
sub property of: bearer of at some time
imported from: vo.owl

has quality at some time
type: ObjectProperty
BFO OWL specification label: has-q_st
range: quality
sub property of: bearer of at some time
imported from: vo.owl

has role at some time
type: ObjectProperty
BFO CLIF specification label: hasRoleAt
BFO OWL specification label: has-r_st
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has role at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has role@en'(x,y,t)
has associated axiom(fol): (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001]
definition: a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001])
range: role
sub property of: bearer of at some time
imported from: obi.owl
imported from: vo.owl

exists at
type: ObjectProperty
editor note: BFO2 Reference: entity
elucidation: b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002])
BFO CLIF specification label: existsAt
editor note: BFO2 Reference: temporal region
BFO OWL specification label: exists-at
domain: entity
range: temporal region
inverse of: during which exists
imported from: ogg.owl
imported from: vo.owl

has continuant part at all times
type: ObjectProperty
type: TransitiveProperty
has associated axiom(fol): (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001]
editor note: [copied from inverse property 'part of continuant at all times that whole exists'] This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times'
definition: [copied from inverse property 'part of continuant at all times that whole exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t)
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has continuant part@en(x,y,t)'.
BFO CLIF specification label: hasContinuantPartAt
definition: b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
BFO OWL specification label: c-has-part_at
sub property of: has continuant part at some time
imported from: ogg.owl
imported from: vo.owl

has occurrent part
type: ObjectProperty
type: TransitiveProperty
editor note: [copied from inverse property 'part of occurrent'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
elucidation: [copied from inverse property 'part of occurrent'] b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002])
example of usage: [copied from inverse property 'part of occurrent'] Mary’s 5th birthday occurrent_part_of Mary’s life
example of usage: [copied from inverse property 'part of occurrent'] The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football.
definition: b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])
BFO OWL specification label: o-has-part
has associated axiom(fol): (iff (hasOccurrentPart a b) (occurrentPartOf b a)) // axiom label in BFO2 CLIF: [007-001]
editor note: [copied from inverse property 'part of occurrent'] BFO2 Reference: occurrent
BFO CLIF specification label: hasOccurrentPart
example of usage: [copied from inverse property 'part of occurrent'] the first set of the tennis match occurrent_part_of the tennis match.
domain: occurrent
range: occurrent
imported from: ogg.owl
imported from: vo.owl

has proper occurrent part
type: ObjectProperty
type: TransitiveProperty
BFO OWL specification label: o-has-ppart
BFO CLIF specification label: hasProperOccurrentPart
definition: [copied from inverse property 'proper part of occurrent'] b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001])
definition: b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001
domain: occurrent
range: occurrent
sub property of: has occurrent part
imported from: ogg.owl
imported from: vo.owl

has temporal part
type: ObjectProperty
type: TransitiveProperty
example of usage: [copied from inverse property 'temporal part of'] the 4th year of your life is a temporal part of your life\. The first quarter of a game of football is a temporal part of the whole game\. The process of your heart beating from 4pm to 5pm today is a temporal part of the entire process of your heart beating.\ The 4th year of your life is a temporal part of your life
example of usage: [copied from inverse property 'temporal part of'] the process boundary which separates the 3rd and 4th years of your life.
definition: [copied from inverse property 'temporal part of'] b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001])
definition: [copied from inverse property 'temporal part of'] b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003])
example of usage: [copied from inverse property 'temporal part of'] your heart beating from 4pm to 5pm today is a temporal part of the process of your heart beating
BFO OWL specification label: has-t-part
range: occurrent
domain: occurrent
sub property of: has occurrent part
imported from: ogg.owl
imported from: vo.owl

has spatial occupant at some time
type: ObjectProperty
BFO OWL specification label: r-location-of_st
elucidation: [copied from inverse property 'occupies spatial region at some time'] b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002])
editor note: [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: independent continuant
editor note: [copied from inverse property 'occupies spatial region at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t)
editor note: [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: spatial region
range: independent continuant
domain: spatial region
imported from: ogg.owl
imported from: vo.owl

has location at some time
type: ObjectProperty
example of usage: [copied from inverse property 'located in at some time'] Mary located_in Salzburg
example of usage: [copied from inverse property 'located in at some time'] the Empire State Building located_in New York.
definition: [copied from inverse property 'located in at some time'] b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
editor note: [copied from inverse property 'located in at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'located in at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'located in@en'(x,y,t)
example of usage: [copied from inverse property 'located in at some time'] your arm located_in your body
example of usage: [copied from inverse property 'located in at some time'] this portion of cocaine located_in this portion of blood
BFO OWL specification label: has-location_st
editor note: [copied from inverse property 'located in at some time'] BFO2 Reference: independent continuant
example of usage: [copied from inverse property 'located in at some time'] this stem cell located_in this portion of bone marrow
domain: independent continuant
range: independent continuant
imported from: vo.owl

has specific dependent at some time
type: ObjectProperty
example of usage: [copied from inverse property 'specifically depends on at some time'] a shape s-depends_on the shaped object
BFO OWL specification label: has-s-dep_st
elucidation: [copied from inverse property 'specifically depends on at some time'] To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: [copied from inverse property 'specifically depends on at some time'] a gait s-depends_on the walking object. (All at some specific time.)
example of usage: [copied from inverse property 'specifically depends on at some time'] A pain s-depends_on the organism that is experiencing the pain
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
example of usage: [copied from inverse property 'specifically depends on at some time'] the two-sided reciprocal s-dependence of the roles of husband and wife [20
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
editor note: [copied from inverse property 'specifically depends on at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t)
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
editor note: [copied from inverse property 'specifically depends on at some time'] BFO2 Reference: specifically dependent continuant\; process; process boundary
example of usage: [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
imported from: ogg.owl
imported from: vo.owl
range: Class
  union of: process
  union of: specifically dependent continuant
domain: Class
  union of: process
  union of: specifically dependent continuant
  union of: Class
    intersection of: independent continuant
    intersection of: Class
      complement of: spatial region

has spatiotemporal occupant
type: ObjectProperty
editor note: [copied from inverse property 'occupies spatiotemporal region'] BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region.
BFO OWL specification label: occupied-by
elucidation: [copied from inverse property 'occupies spatiotemporal region'] p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003])
range: occurrent
domain: spatiotemporal region
imported from: ogg.owl
imported from: vo.owl

occupies spatiotemporal region
type: ObjectProperty
BFO CLIF specification label: occupiesSpatiotemporalRegion
editor note: BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region.
BFO OWL specification label: occupies
elucidation: p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003])
domain: occurrent
range: spatiotemporal region
inverse of: has spatiotemporal occupant
imported from: ogg.owl
imported from: vo.owl

part of occurrent
type: ObjectProperty
type: TransitiveProperty
editor note: BFO2 Reference: occurrent
BFO CLIF specification label: occurrentPartOf
BFO OWL specification label: o-part-of
has associated axiom(fol): (forall (x y t) (if (and (occurrentPartOf x y t) (not (= x y))) (exists (z) (and (occurrentPartOf z y t) (not (exists (w) (and (occurrentPartOf w x t) (occurrentPartOf w z t)))))))) // axiom label in BFO2 CLIF: [124-001]
has associated axiom(fol): (forall (x y t) (if (and (occurrentPartOf x y t) (occurrentPartOf y x t)) (= x y))) // axiom label in BFO2 CLIF: [123-001]
definition: [copied from inverse property 'has occurrent part'] b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])
has associated axiom(fol): (forall (x) (if (Occurrent x) (occurrentPartOf x x))) // axiom label in BFO2 CLIF: [113-002]
has associated axiom(fol): (forall (x y z) (if (and (occurrentPartOf x y) (occurrentPartOf y z)) (occurrentPartOf x z))) // axiom label in BFO2 CLIF: [112-001]
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (occurrentPartOf v x t) (occurrentPartOf v y t))) (exists (z) (forall (u w) (iff (iff (occurrentPartOf w u t) (and (occurrentPartOf w x t) (occurrentPartOf w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [125-001]
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
example of usage: Mary’s 5th birthday occurrent_part_of Mary’s life
example of usage: The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football.
elucidation: b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002])
has associated axiom(nl): occurrent_part_of is antisymmetric. (axiom label in BFO2 Reference: [123-001])
has associated axiom(nl): occurrent_part_of is reflexive (every occurrent entity is an occurrent_part_of itself). (axiom label in BFO2 Reference: [113-002])
has associated axiom(nl): occurrent_part_of is transitive. (axiom label in BFO2 Reference: [112-001])
has associated axiom(nl): occurrent_part_of satisfies unique product. (axiom label in BFO2 Reference: [125-001])
has associated axiom(nl): occurrent_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [124-001])
example of usage: the first set of the tennis match occurrent_part_of the tennis match.
range: occurrent
domain: occurrent
inverse of: has occurrent part
imported from: ogg.owl
imported from: vo.owl

temporal part of
type: ObjectProperty
type: TransitiveProperty
has associated axiom(fol): (iff (properTemporalPartOf a b) (and (temporalPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [116-001]
has associated axiom(fol): (forall (x y) (if (properTemporalPartOf x y) (exists (z) (and (properTemporalPartOf z y) (not (exists (w) (and (temporalPartOf w x) (temporalPartOf w z)))))))) // axiom label in BFO2 CLIF: [117-002]
definition: b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003])
BFO CLIF specification label: temporalPartOf
BFO OWL specification label: t-part-of
has associated axiom(fol): (iff (temporalPartOf a b) (and (occurrentPartOf a b) (exists (t) (and (TemporalRegion t) (occupiesSpatioTemporalRegion a t))) (forall (c t_1) (if (and (Occurrent c) (occupiesSpatioTemporalRegion c t_1) (occurrentPartOf t_1 r)) (iff (occurrentPartOf c a) (occurrentPartOf c b)))))) // axiom label in BFO2 CLIF: [078-003]
definition: b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001])
has associated axiom(nl): if b proper_temporal_part_of c, then there is some d which is a proper_temporal_part_of c and which shares no parts with b. (axiom label in BFO2 Reference: [117-002])
example of usage: the 4th year of your life is a temporal part of your life\. The first quarter of a game of football is a temporal part of the whole game\. The process of your heart beating from 4pm to 5pm today is a temporal part of the entire process of your heart beating.\ The 4th year of your life is a temporal part of your life
example of usage: the process boundary which separates the 3rd and 4th years of your life.
example of usage: your heart beating from 4pm to 5pm today is a temporal part of the process of your heart beating
domain: occurrent
range: occurrent
inverse of: has temporal part
sub property of: part of occurrent
imported from: ogg.owl
imported from: vo.owl

projects onto spatial region at some time
type: ObjectProperty
BFO OWL specification label: st-projects-onto-s_st
range: spatial region
domain: spatiotemporal region
inverse of: spatial projection of spatiotemporal at some time
imported from: ogg.owl
imported from: vo.owl

spatial projection of spatiotemporal at some time
type: ObjectProperty
BFO OWL specification label: s-projection-of-st_st
domain: spatial region
range: spatiotemporal region
imported from: ogg.owl
imported from: vo.owl

projects onto temporal region
type: ObjectProperty
BFO OWL specification label: st-projects-onto-t
range: temporal region
domain: spatiotemporal region
sub property of: exists at
inverse of: temporal projection of spatiotemporal
imported from: ogg.owl
imported from: vo.owl

temporal projection of spatiotemporal
type: ObjectProperty
BFO OWL specification label: t-projection-of-st
domain: temporal region
range: spatiotemporal region
sub property of: during which exists
imported from: ogg.owl
imported from: vo.owl

occupies temporal region
type: ObjectProperty
BFO OWL specification label: spans
BFO CLIF specification label: occupiesTemporalRegion
elucidation: p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])
domain: occurrent
range: temporal region
sub property of: exists at
inverse of: has temporal occupant
imported from: ogg.owl
imported from: vo.owl

has temporal occupant
type: ObjectProperty
elucidation: [copied from inverse property 'occupies temporal region'] p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])
BFO OWL specification label: span-of
BFO CLIF specification label: spanOf
range: occurrent
domain: temporal region
sub property of: during which exists
imported from: ogg.owl
imported from: vo.owl

during which exists
type: ObjectProperty
editor note: [copied from inverse property 'exists at'] BFO2 Reference: entity
BFO OWL specification label: during-which-exists
editor note: [copied from inverse property 'exists at'] BFO2 Reference: temporal region
elucidation: [copied from inverse property 'exists at'] b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002])
range: entity
domain: temporal region
imported from: ogg.owl
imported from: vo.owl

bearer of at all times
type: ObjectProperty
has associated axiom(fol): (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004]
BFO CLIF specification label: bearerOfAt
editor note: BFO2 Reference: independent continuant that is not a spatial region
BFO OWL specification label: bearer-of_at
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'bearer of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'bearer of@en(x,y,t)'.
editor note: BFO2 Reference: specifically dependent continuant
definition: b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])
range: specifically dependent continuant
sub property of: has specific dependent at all times
imported from: ogg.owl
imported from: vo.owl
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region

has quality at all times
type: ObjectProperty
BFO OWL specification label: has-q_at
range: quality
sub property of: bearer of at all times
imported from: vo.owl

has role at all times
type: ObjectProperty
BFO CLIF specification label: hasRoleAt
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has role at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has role@en(x,y,t)'.
BFO OWL specification label: has-r_at
has associated axiom(fol): (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001]
definition: a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001])
range: role
sub property of: bearer of at all times
imported from: vo.owl

has participant at all times
type: ObjectProperty
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has participant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has participant@en(x,y,t)'.
BFO OWL specification label: has-participant_at
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003]
editor note: BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001]
editor note: BFO2 Reference: process
BFO CLIF specification label: hasParticipantAt
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001]
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
elucidation: has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])
has associated axiom(nl): if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003])
has associated axiom(nl): if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003])
has associated axiom(nl): if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001])
has associated axiom(nl): if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001])
has associated axiom(nl): if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001])
domain: process
sub property of: has participant
imported from: vo.owl
range: Class
  intersection of: continuant
  intersection of: Class
    complement of: spatial region

has specific dependent at all times
type: ObjectProperty
BFO OWL specification label: has-s-dep_at
sub property of: has specific dependent at some time
imported from: ogg.owl
imported from: vo.owl

specifically depends on at some time
type: ObjectProperty
BFO OWL specification label: s-depends-on_st
editor note: BFO2 Reference: specifically dependent continuant\; process; process boundary
has associated axiom(fol): (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]
has associated axiom(fol): (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
editor note: BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
has associated axiom(nl): If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
elucidation: To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64
example of usage: one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
BFO CLIF specification label: specificallyDependsOn
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t)
has associated axiom(fol): (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
has associated axiom(fol): (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
has associated axiom(fol): (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
example of usage: A pain s-depends_on the organism that is experiencing the pain
editor note: BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
has associated axiom(nl): If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has associated axiom(nl): If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
example of usage: a gait s-depends_on the walking object. (All at some specific time.)
example of usage: a shape s-depends_on the shaped object
has associated axiom(nl): an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
has associated axiom(nl): if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: the two-sided reciprocal s-dependence of the roles of husband and wife [20
inverse of: has specific dependent at some time
imported from: ogg.owl
imported from: vo.owl
domain: Class
  union of: process
  union of: specifically dependent continuant
range: Class
  union of: process
  union of: specifically dependent continuant
  union of: Class
    intersection of: independent continuant
    intersection of: Class
      complement of: spatial region

located in at some time
type: ObjectProperty
has associated axiom(fol): (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001]
BFO CLIF specification label: locatedInAt
editor note: BFO2 Reference: independent continuant
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001]
BFO OWL specification label: located-in_st
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001]
has associated axiom(fol): (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001]
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'located in at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'located in@en'(x,y,t)
has associated axiom(nl): Located_in is transitive. (axiom label in BFO2 Reference: [046-001])
example of usage: Mary located_in Salzburg
definition: b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001])
example of usage: the Empire State Building located_in New York.
example of usage: this portion of cocaine located_in this portion of blood
example of usage: this stem cell located_in this portion of bone marrow
example of usage: your arm located_in your body
domain: independent continuant
range: independent continuant
inverse of: has location at some time
imported from: vo.owl

part of continuant at some time
type: ObjectProperty
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
editor note: [copied from inverse property 'has continuant part at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t)
editor note: BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
definition: [copied from inverse property 'has continuant part at some time'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
has associated axiom(fol): (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]
has associated axiom(fol): (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
has associated axiom(fol): (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
editor note: BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
BFO OWL specification label: c-part-of_st
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: BFO2 Reference: continuant
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
example of usage: Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
BFO CLIF specification label: continuantPartOfAt
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t)
elucidation: b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has associated axiom(nl): continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
has associated axiom(nl): continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
has associated axiom(nl): continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
has associated axiom(nl): continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
has associated axiom(nl): continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
has associated axiom(nl): if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
example of usage: the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
range: continuant
domain: continuant
inverse of: has continuant part at some time
imported from: ogg.owl
imported from: vo.owl

part of continuant at all times
type: ObjectProperty
type: TransitiveProperty
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
editor note: BFO2 Reference: continuant
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
BFO CLIF specification label: continuantPartOfAt
has associated axiom(fol): (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
definition: [copied from inverse property 'has continuant part at all times that part exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
BFO OWL specification label: c-part-of_at
editor note: BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'.
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
has associated axiom(fol): (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
has associated axiom(fol): (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]
editor note: BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
example of usage: Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
editor note: [copied from inverse property 'has continuant part at all times that part exists'] This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
elucidation: b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has associated axiom(nl): continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
has associated axiom(nl): continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
has associated axiom(nl): continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
has associated axiom(nl): continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
has associated axiom(nl): continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
has associated axiom(nl): if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
example of usage: the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
sub property of: part of continuant at some time
imported from: ogg.owl
imported from: vo.owl

has continuant part at some time
type: ObjectProperty
editor note: [copied from inverse property 'part of continuant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t)
elucidation: [copied from inverse property 'part of continuant at some time'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
example of usage: [copied from inverse property 'part of continuant at some time'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
has associated axiom(fol): (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001]
BFO OWL specification label: c-has-part_st
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t)
editor note: [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuant
editor note: [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
BFO CLIF specification label: hasContinuantPartAt
example of usage: [copied from inverse property 'part of continuant at some time'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
editor note: [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
definition: b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
range: continuant
domain: continuant
imported from: ogg.owl
imported from: vo.owl

part of continuant at all times that whole exists
type: ObjectProperty
type: TransitiveProperty
editor note: [copied from inverse property 'has continuant part at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has continuant part@en(x,y,t)'.
editor note: This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times'
definition: forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t)
definition: [copied from inverse property 'has continuant part at all times'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
BFO OWL specification label: c-part-of-object_at
domain: continuant
range: continuant
inverse of: has continuant part at all times
sub property of: part of continuant at some time
imported from: ogg.owl
imported from: vo.owl

has continuant part at all times that part exists
type: ObjectProperty
type: TransitiveProperty
editor note: [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuant
example of usage: [copied from inverse property 'part of continuant at all times'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
BFO OWL specification label: c-has-part-object_at
definition: forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
elucidation: [copied from inverse property 'part of continuant at all times'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
example of usage: [copied from inverse property 'part of continuant at all times'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
editor note: This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
editor note: [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
editor note: [copied from inverse property 'part of continuant at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'.
editor note: [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
range: continuant
domain: continuant
inverse of: part of continuant at all times
sub property of: has continuant part at some time
imported from: ogg.owl
imported from: vo.owl

is about
type: ObjectProperty
definition source: Smith, Ceusters, Ruttenberg, 2000 years of philosophy
example of usage: This document is about information artifacts and their representations
editor preferred term: is about
definition: is_about is a (currently) primitive relation that relates an information artifact to an entity.
term editor: person:Alan Ruttenberg
domain: information content entity
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl

is associated with review board approval number
type: ObjectProperty
creator: EE, YH, YL, AK, MH
creator: a relation that links an informed consent form to an associated IRB number
domain: informed consent form
range: review board approval number
imported from: ico.owl

is assigned by organization
type: ObjectProperty
definition: an object perperty that represents a relation between a unique identifier (ID) and an organization that assigns the ID.
creator: YH, EE, YL, AK, MH
imported from: ico.owl

has participant quality
type: ObjectProperty

adverse event occurs in
type: ObjectProperty

is_supported_by_data
type: ObjectProperty
definition source: Philly 2011 workshop
definition: The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process
example of usage: The relation between the conclusion "Gene tpbA is involved in EPS production" and the data items produced using two sets of organisms, one being a tpbA knockout, the other being tpbA wildtype tested in polysacharide production assays and analyzed using an ANOVA.
editor preferred term: is_supported_by_data
definition source: OBI
term editor: OBI
range: data item
has curation status: ready for release
domain: conclusion based on data
imported from: ico.owl
imported from: obi.owl

is_specified_input_of
type: ObjectProperty
term editor: PERSON:Bjoern Peters
editor preferred term: is_specified_input_of
definition: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
term editor: Alan Ruttenberg
example of usage: some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay
sub property of: participates_in
has curation status: ready for release
range: planned process
sub property of: participates in
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl

is_manufactured_by
type: ObjectProperty
term editor: Alan Ruttenberg
term editor: Liju Fan
definition: c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the "Manufacturer Role", and those people/and or machines were members or of directed by the organization to do this.
alternative term: has_make
alternative term: has_manufacturer
example of usage: http://www.affymetrix.com/products/arrays/specific/hgu133.affx is_manufactered_by http://www.affymetrix.com/ (if we decide to use these URIs for the actual entities)
editor preferred term: is_manufactured_by
imported from: obi.owl
imported from: vo.owl

is_specified_output_of
type: ObjectProperty
term editor: PERSON:Bjoern Peters
editor preferred term: is_specified_output_of
definition: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
term editor: Alan Ruttenberg
sub property of: participates_in
has curation status: ready for release
range: planned process
sub property of: participates in
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl

achieves_planned_objective
type: ObjectProperty
example of usage: A cell sorting process achieves the objective specification 'material separation objective'
term editor: BP, AR, PPPB branch
definition source: PPPB branch derived
definition: This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
editor preferred term: achieves_planned_objective
curator notes: modified according to email thread from 1/23/09 in accordince with DT and PPPB branch
imported from: obi.owl
imported from: vo.owl

objective_achieved_by
type: ObjectProperty
definition: This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
editor preferred term: objective_achieved_by
term editor: OBI
definition source: OBI
domain: objective specification
has curation status: ready for release
range: planned process
imported from: ico.owl
imported from: obi.owl

is genome of organism
type: ObjectProperty
definition: a 'part of continuant at some time' relation that incides a genome belongs to a organism.
term editor: Yongqun He, Bin Zhao
sub property of: part of continuant at some time
imported from: ogg.owl
imported from: vo.owl

is gene of organism
type: ObjectProperty
term editor: Oliver He, Yue Liu
definition: a relation between a gene and the organism where this gene belongs to the organism in nature. It does not include a foreign gene that is transferred to an organism by a genetic engineering method.
sub property of: part of continuant at some time
range: organism
imported from: ogg.owl
imported from: vo.owl

inheres in
type: ObjectProperty
editor note: A dependent inheres in its bearer at all times for which the dependent exists.
definition: a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence
editor preferred term: inheres in
alternative term: inheres_in
example of usage: this fragility inheres in this vase
example of usage: this red color inheres in this apple
inverse of: bearer of
temporal interpretation: axiom holds for all times
imported from: ico.owl
imported from: obi.owl

bearer of
type: ObjectProperty
editor note: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
definition: a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence
editor preferred term: bearer of
alternative term: bearer_of
alternative term: is bearer of
example of usage: this apple is bearer of this red color
example of usage: this vase is bearer of this fragility
range: specifically dependent continuant
temporal interpretation: axiom holds for all times
imported from: ico.owl
imported from: obi.owl
imported from: ro.owl

participates in
type: ObjectProperty
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
editor preferred term: participates in
alternative term: participates_in
example of usage: this blood clot participates in this blood coagulation
example of usage: this input material (or this output material) participates in this process
example of usage: this investigator participates in this investigation
domain: continuant
range: occurrent
inverse of: has participant
imported from: ico.owl
imported from: obi.owl

has participant
type: ObjectProperty
editor note: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
editor preferred term: has participant
Source: http://www.obofoundry.org/ro/#OBO_REL:has_participant
alternative term: has_participant
example of usage: this blood coagulation has participant this blood clot
example of usage: this investigation has participant this investigator
example of usage: this process has participant this input material (or this output material)
range: continuant
domain: occurrent
imported from: ico.owl
imported from: obi.owl

concretizes
type: ObjectProperty
example of usage: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
definition: A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant.
example of usage: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
editor preferred term: concretizes
domain: specifically dependent continuant
range: generically dependent continuant
imported from: ico.owl
imported from: obi.owl

has quality
type: ObjectProperty
editor note: A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.
definition: a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
alternative term: has_quality
example of usage: this apple has quality this red color
range: quality
sub property of: bearer of
imported from: ro.owl

has role
type: ObjectProperty
editor note: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
editor preferred term: has role
alternative term: has_role
example of usage: this person has role this investigator role (more colloquially: this person has this role of investigator)
domain: independent continuant
range: role
sub property of: bearer of
imported from: ico.owl
imported from: obi.owl

located_in
type: ObjectProperty
type: TransitiveProperty
label: located_in (type level)
label: located in
database_cross_reference: RO:0001025
has_obo_namespace: file:/Users/michaelashburner/Desktop/gaz/gaz.obo
id: located_in
shorthand: located_in
Source: http://www.obofoundry.org/ro/#OBO_REL:located_in
editor note: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
definition: a relation between two independent continuants, the target and the location, in which the target is entirely within the location
editor preferred term: located in
alternative term: located_in
example of usage: my brain is located in my head
example of usage: this rat is located in this cage
temporal interpretation: axiom holds for all times
imported from: gaz.owl
property chain axiom: subClassOf

has component
type: ObjectProperty
curator notes: For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.
definition: w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
editor note: The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.
sub property of: has part
has curation status: pending final vetting
temporal interpretation: axiom holds for all times
imported from: ro.owl
in_subset: eco subset

is about vaccination procedure
type: ObjectProperty
definition: a relation between a question or a questionnaire that is specifically designed for a certain vaccination procedure.
comment: It is not clear if all questionnaires use the same question for a certain vaccination. If it is true, this relation is class level relation. If not, it is instance level relation. However, in a questionnaire and vaccination procedure, this is always true.
sub property of: is about
range: vaccination

asking vaccination patient
type: ObjectProperty
sub property of: is about
range: vaccination patient
domain: Class
  union of: question textual entity
  union of: vaccination screening questionnaire

documented by
type: ObjectProperty
term editor: YH,YL, JZ
definition: an object property that represents a relation between a document and an entity that writes, maintains and releases the document.

screening questionnaire is filled by
type: ObjectProperty
sub property of: is about
domain: vaccination screening questionnaire
range: Class
  union of: legal representative of minor vaccination patient
  union of: Class
    intersection of: vaccination patient
    intersection of: Class
      complement of: minor vaccination patient

used in geographic location
type: ObjectProperty
sub property of: is about

has gender
type: ObjectProperty
sub property of: has quality

has vaccine contraindication
type: ObjectProperty
editor note: This relation may be replaced by has_vaccine_allergen. We need to determine if any vaccine contraindicator is not a vaccine allergen.
term editor: YH
definition: has_vaccine_contraindication is a relation that specifies contraindication of a vaccine.
imported from: vo.owl

has vaccine allergen
type: ObjectProperty
definition: a object property that specifies a relation between a vaccine and a vaccine allergen
term editor: YH
domain: vaccine
imported from: vo.owl
sub property of: topObjectProperty

vaccinated in route
type: ObjectProperty
comment: an object property that specifies a relation between a vaccine and a vaccinate route
domain: vaccine
range: route of administration
imported from: vo.owl

is_distributed_by
type: ObjectProperty
definition: is_distributed_by is a relation that specifies a company that distributes a product (e.g., vaccine). The company is very likely not the manufacturer of the product.
term editor: YH, ZX
imported from: vo.owl

vaccine immunization against disase
type: ObjectProperty
term editor: Oliver He
term editor: Asiyah Yu Lin
domain: vaccine
imported from: vo.owl

vaccine immunization for host
type: ObjectProperty
term editor: Yongqun He
term editor: YL
range: organism
domain: vaccine
imported from: vo.owl

vaccine immunization against microbe
type: ObjectProperty
term editor: Yongqun He
imported from: vo.owl

bearer_of
type: ObjectProperty
imported from: http://purl.org/obo/owl/ro_proposed
definition: A relation between an entity and a dependent continuant; the reciprocal relation of inheres_in
editor preferred term: bearer_of
imported from: vo.owl

inheres_in
type: ObjectProperty
type: FunctionalProperty
imported from: http://purl.org/obo/owl/ro_proposed
definition: A relation between a dependent continuant D and an entity E. D inheres_in E iff: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation.
editor preferred term: inheres_in
range: independent continuant
domain: specifically dependent continuant
sub property of: inheres_in_part_of
imported from: vo.owl

inheres_in_part_of
type: ObjectProperty
imported from: http://purl.org/obo/owl/ro_proposed
editor preferred term: inheres_in_part_of
imported from: vo.owl

role_of
type: ObjectProperty
imported from: http://purl.org/obo/owl/ro_proposed
definition: A relation between a role R and an entity E. R role_of E iff: R inheres_in E and R is a role
editor preferred term: role_of
sub property of: inheres_in
imported from: vo.owl

unfolds_in
type: ObjectProperty
imported from: http://purl.org/obo/owl/ro_proposed
definition: P unfolds_in C : the execution of P is spatially contained by C. forall pP, forall c' partipates_in p, c' located_in C at t, for some t in P
editor preferred term: unfolds_in
imported from: vo.owl

hasAge
type: DatatypeProperty

entity
type: Class
subclass of: Restriction
  on property: exists at
  some values from: temporal region
BFO OWL specification label: entity
editor note: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
BFO CLIF specification label: Entity
elucidation: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
editor note: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
example of usage: Julius Caesar
example of usage: Verdi’s Requiem
editor preferred term: entity
example of usage: the Second World War
example of usage: your body mass index
imported from: BFO
imported from: bfo.owl
imported from: ico.owl
imported from: oae.owl
imported from: obi.owl
imported from: ogg.owl
imported from: ogms.owl
imported from: vo.owl

continuant
type: Class
subclass of: entity
BFO CLIF specification label: Continuant
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has associated axiom(fol): (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has associated axiom(fol): (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
elucidation: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
BFO OWL specification label: continuant
definition: An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
editor note: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
editor note: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
example of usage: a heart
example of usage: a person
example of usage: a symphony orchestra
editor preferred term: continuant
alternative term: endurant
has associated axiom(nl): if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has associated axiom(nl): if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has associated axiom(nl): if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
example of usage: the color of a tomato
example of usage: the disposition of blood to coagulate
example of usage: the lawn and atmosphere in front of our building
example of usage: the mass of a cloud
imported from: BFO
imported from: bfo.owl
imported from: ico.owl
imported from: oae.owl
imported from: obi.owl
imported from: ogg.owl
imported from: ro.owl
imported from: vo.owl

occurrent
type: Class
subclass of: entity
has associated axiom(fol): (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]
editor note: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
has associated axiom(fol): (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
definition: An entity that has temporal parts and that happens, unfolds or develops through time.
elucidation: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
editor note: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region
editor note: BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.
BFO CLIF specification label: Occurrent
editor note: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
BFO OWL specification label: occurrent
has associated axiom(nl): Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has associated axiom(nl): b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
editor preferred term: occurrent
imported from: BFO
imported from: ico.owl
imported from: oae.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

independent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: specifically depends on at some time
  all values from: Nothing
subclass of: Restriction
  on property: occupies spatial region at some time
  some values from: spatial region
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: Class
    complement of: Class
      union of: specifically dependent continuant
      union of: generically dependent continuant
subclass of: Restriction
  on property: part of continuant at some time
  all values from: Class
    complement of: Class
      union of: specifically dependent continuant
      union of: generically dependent continuant
BFO CLIF specification label: IndependentContinuant
has associated axiom(fol): (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has associated axiom(fol): (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
has associated axiom(fol): (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
definition: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
example of usage: a leg
BFO OWL specification label: ic
has associated axiom(nl): For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has associated axiom(nl): For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
example of usage: a chair
example of usage: a heart
example of usage: a molecule
example of usage: a person
example of usage: a spatial region
example of usage: a symphony orchestra
example of usage: an atom
example of usage: an orchestra.
example of usage: an organism
definition: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
editor preferred term: independent continuant
alternative term: substantial entity
example of usage: the bottom right portion of a human torso
example of usage: the interior of your mouth
example of usage: the lawn and atmosphere in front of our building
imported from: BFO
imported from: bfo.owl
imported from: ico.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

spatial region
type: Class
subclass of: immaterial entity
subclass of: Restriction
  on property: part of continuant at some time
  all values from: spatial region
subclass of: Restriction
  on property: occupies spatial region at some time
  has self: true
subclass of: Restriction
  on property: has spatial occupant at some time
  has self: true
subclass of: Restriction
  on property: has continuant part at all times that part exists
  all values from: spatial region
subclass of: Restriction
  on property: has continuant part at some time
  all values from: spatial region
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: spatial region
has associated axiom(fol): (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]
BFO OWL specification label: s-region
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
BFO CLIF specification label: SpatialRegion
has associated axiom(fol): (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
elucidation: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has associated axiom(nl): All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
editor note: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
imported from: ogg.owl
imported from: vo.owl

temporal region
type: Class
subclass of: occurrent
subclass of: Restriction
  on property: has temporal occupant
  has self: true
subclass of: Restriction
  on property: has occurrent part
  all values from: temporal region
subclass of: Restriction
  on property: part of occurrent
  all values from: temporal region
subclass of: Restriction
  on property: occupies temporal region
  has self: true
has associated axiom(fol): (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001]
has associated axiom(nl): Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])
editor note: Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional
BFO CLIF specification label: TemporalRegion
BFO OWL specification label: t-region
has associated axiom(fol): (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002]
has associated axiom(fol): (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001]
elucidation: A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])
has associated axiom(nl): All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])
imported from: ogg.owl
imported from: vo.owl

spatiotemporal region
type: Class
subclass of: occurrent
subclass of: Restriction
  on property: projects onto spatial region at some time
  some values from: spatial region
subclass of: Restriction
  on property: has occurrent part
  all values from: spatiotemporal region
subclass of: Restriction
  on property: occupies spatiotemporal region
  has self: true
subclass of: Restriction
  on property: part of occurrent
  all values from: spatiotemporal region
subclass of: Restriction
  on property: projects onto temporal region
  some values from: temporal region
subclass of: Restriction
  on property: has spatiotemporal occupant
  has self: true
BFO OWL specification label: st-region
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001]
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001]
has associated axiom(fol): (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001]
has associated axiom(fol): (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002]
has associated axiom(nl): Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])
has associated axiom(nl): Every spatiotemporal region occupies_spatiotemporal_region itself.
BFO CLIF specification label: SpatiotemporalRegion
has associated axiom(fol): (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001]
elucidation: A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])
has associated axiom(nl): All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])
has associated axiom(nl): Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])
has associated axiom(nl): Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])
example of usage: the spatiotemporal region occupied by a human life
example of usage: the spatiotemporal region occupied by a process of cellular meiosis.
example of usage: the spatiotemporal region occupied by the development of a cancer tumor
imported from: ogg.owl
imported from: vo.owl

process
type: Class
subclass of: occurrent
subclass of: Restriction
  on property: part of occurrent
  all values from: process
subclass of: Restriction
  on property: specifically depends on at some time
  some values from: material entity
subclass of: Restriction
  on property: has occurrent part
  all values from: Class
    union of: process
    union of: process boundary
has associated axiom(fol): (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]
definition: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
BFO OWL specification label: process
BFO CLIF specification label: Process
editor note: BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)
example of usage: a process of cell-division, \ a beating of the heart
example of usage: a process of meiosis
example of usage: a process of sleeping
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
editor preferred term: process
example of usage: the course of a disease
example of usage: the flight of a bird
example of usage: the life of an organism
example of usage: your process of aging.
imported from: BFO
imported from: ico.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

disposition
type: Class
subclass of: realizable entity
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: Class
    complement of: role
subclass of: Restriction
  on property: part of continuant at some time
  all values from: Class
    complement of: role
has associated axiom(fol): (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]
editor note: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.
BFO CLIF specification label: Disposition
has associated axiom(fol): (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
editor note: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type [89
BFO OWL specification label: disposition
has associated axiom(nl): If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
example of usage: an atom of element X has the disposition to decay to an atom of element Y
elucidation: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
example of usage: certain people have a predisposition to colon cancer
example of usage: children are innately disposed to categorize objects in certain ways.
example of usage: the cell wall is disposed to filter chemicals in endocitosis and exocitosis
example of usage: the cell wall is disposed to filter chemicals in endocytosis and exocytosis
imported from: oae.owl
imported from: ogg.owl
imported from: vo.owl

realizable entity
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
  on property: part of continuant at some time
  all values from: Class
    complement of: quality
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: Class
    complement of: quality
definition: A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
has associated axiom(nl): All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
BFO CLIF specification label: RealizableEntity
BFO OWL specification label: realizable
has associated axiom(fol): (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]
has associated axiom(fol): (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
editor note: If a realizable entity [snap:RealizableEntity] inheres in a continuant [snap:Continuant], this does not imply that it is actually realized.
elucidation: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
editor preferred term: realizable entity
example of usage: the disposition of blood to coagulate
example of usage: the disposition of metal to conduct electricity
example of usage: the disposition of this piece of metal to conduct electricity.
example of usage: the disposition of your blood to coagulate
example of usage: the function of the reproductive organs
example of usage: the function of your reproductive organs
example of usage: the role of being a doctor
example of usage: the role of this boundary to delineate where Utah and Colorado meet
imported from: ico.owl
imported from: oae.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

quality
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
  on property: part of continuant at some time
  all values from: Class
    complement of: realizable entity
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: Class
    complement of: realizable entity
has associated axiom(fol): (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
BFO OWL specification label: quality
BFO CLIF specification label: Quality
has associated axiom(fol): (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]
has associated axiom(nl): If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
elucidation: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
example of usage: the ambient temperature of this portion of air
example of usage: the color of a tomato
example of usage: the length of the circumference of your waist
example of usage: the mass of this piece of gold.
example of usage: the shape of your nose
example of usage: the shape of your nostril
imported from: ogg.owl
imported from: ro.owl
imported from: vo.owl

specifically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: Class
    complement of: Class
      union of: independent continuant
      union of: generically dependent continuant
subclass of: Restriction
  on property: part of continuant at some time
  all values from: Class
    complement of: Class
      union of: independent continuant
      union of: generically dependent continuant
subclass of: Restriction
  on property: inheres in at all times
  some values from: Class
    intersection of: independent continuant
    intersection of: Class
      complement of: spatial region
has associated axiom(fol): (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
has associated axiom(fol): (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004]
BFO CLIF specification label: SpecificallyDependentContinuant
definition: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
editor note: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
definition: b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
definition: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
example of usage: of one-sided specifically dependent continuants: the mass of this tomato
example of usage: of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
BFO OWL specification label: sdc
example of usage: Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
alternative term: mode
alternative term: property
editor preferred term: specifically dependent continuant
example of usage: the color of a tomato
example of usage: the disposition of fish to decay
example of usage: the disposition of this fish to decay
example of usage: the function of the heart in the body: to pump blood, to receive de-oxygenated and oxygenated blood, etc.
example of usage: the function of this heart: to pump blood
example of usage: the liquidity of blood
example of usage: the mass of a cloud
example of usage: the mutual dependence of proton donors and acceptors in chemical reactions [79
example of usage: the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
example of usage: the pink color of a medium rare piece of grilled filet mignon at its center
example of usage: the role of being a doctor
example of usage: the shape of this hole.
example of usage: the smell of mozzarella
example of usage: the smell of this portion of mozzarella
alternative term: trope
imported from: ico.owl
imported from: oae.owl
imported from: obi.owl
imported from: ogg.owl
imported from: ro.owl
imported from: vo.owl

role
type: Class
subclass of: realizable entity
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: Class
    complement of: disposition
subclass of: Restriction
  on property: part of continuant at some time
  all values from: Class
    complement of: disposition
BFO CLIF specification label: Role
BFO OWL specification label: role
has associated axiom(fol): (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]
definition: A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
editor note: BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.
example of usage: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
elucidation: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
editor preferred term: role
example of usage: the priest role
example of usage: the role of a biological grandfather as legal guardian in the context of a system of laws
example of usage: the role of a boundary to demarcate two neighboring administrative territories
example of usage: the role of a building in serving as a military target
example of usage: the role of a chemical compound in an experiment
example of usage: the role of a patient relative as defined by a hospital administrative form
example of usage: the role of a person as a surgeon
example of usage: the role of a stone in marking a property boundary
example of usage: the role of a student in a university
example of usage: the role of a woman as a legal mother in the context of system of laws
example of usage: the role of ingested matter in digestion
example of usage: the role of subject in a clinical trial
example of usage: the student role
imported from: ico.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

three-dimensional spatial region
type: Class
subclass of: spatial region
BFO CLIF specification label: ThreeDimensionalSpatialRegion
BFO OWL specification label: 3d-s-region
has associated axiom(fol): (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001]
elucidation: A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])
example of usage: a cube-shaped region of space
example of usage: a sphere-shaped region of space,
imported from: ogg.owl
imported from: vo.owl

site
type: Class
subclass of: immaterial entity
BFO OWL specification label: site
BFO CLIF specification label: Site
has associated axiom(fol): (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002]
example of usage: Manhattan Canyon)
example of usage: a hole in the interior of a portion of cheese
example of usage: a rabbit hole
example of usage: an air traffic control region defined in the airspace above an airport
elucidation: b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])
example of usage: the Grand Canyon
example of usage: the Piazza San Marco
example of usage: the cockpit of an aircraft
example of usage: the hold of a ship
example of usage: the interior of a kangaroo pouch
example of usage: the interior of the trunk of your car
example of usage: the interior of your bedroom
example of usage: the interior of your office
example of usage: the interior of your refrigerator
example of usage: the lumen of your gut
example of usage: your left nostril (a fiat part – the opening – of your left nasal cavity)
imported from: bfo.owl

generically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
  on property: concretized by at some time
  some values from: specifically dependent continuant
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: Class
    complement of: Class
      union of: independent continuant
      union of: specifically dependent continuant
subclass of: Restriction
  on property: part of continuant at some time
  all values from: Class
    complement of: Class
      union of: independent continuant
      union of: specifically dependent continuant
BFO OWL specification label: gdc
has associated axiom(fol): (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
BFO CLIF specification label: GenericallyDependentContinuant
definition: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
example of usage: The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.
example of usage: a certain PDF file that exists in different and in several hard drives
definition: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
editor preferred term: generically dependent continuant
example of usage: the pdf file on your laptop, the pdf file that is a copy thereof on my laptop
example of usage: the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.
imported from: ico.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

process boundary
type: Class
subclass of: occurrent
subclass of: Restriction
  on property: occupies spatiotemporal region
  all values from: Class
    intersection of: spatiotemporal region
    intersection of: Restriction
      on property: temporal part of
      some values from: spatiotemporal region
subclass of: Restriction
  on property: exists at
  all values from: zero-dimensional temporal region
subclass of: Restriction
  on property: has occurrent part
  all values from: process boundary
subclass of: Restriction
  on property: part of occurrent
  all values from: Class
    union of: process
    union of: process boundary
has associated axiom(fol): (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002]
has associated axiom(fol): (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001]
has associated axiom(nl): Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])
BFO OWL specification label: p-boundary
BFO CLIF specification label: ProcessBoundary
definition: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
example of usage: the boundary between the 2nd and 3rd year of your life.
imported from: ogg.owl
imported from: vo.owl

material entity
type: Class
subclass of: independent continuant
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: material entity
subclass of: Restriction
  on property: has continuant part at all times that part exists
  all values from: Class
    union of: material entity
    union of: immaterial entity
subclass of: Restriction
  on property: occupies spatial region at some time
  all values from: three-dimensional spatial region
subclass of: Restriction
  on property: has continuant part at some time
  all values from: Class
    union of: material entity
    union of: immaterial entity
subclass of: Restriction
  on property: part of continuant at some time
  all values from: material entity
BFO OWL specification label: material
has associated axiom(fol): (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
elucidation: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
definition: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
BFO CLIF specification label: MaterialEntity
editor note: BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
editor note: BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
editor note: BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
has associated axiom(nl): Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
editor note: Examples: collection of random bacteria, a chair, dorsal surface of the body
editor note: Material entity [snap:MaterialEntity] subsumes object [snap:Object], fiat object part [snap:FiatObjectPart], and object aggregate [snap:ObjectAggregate], which assume a three level theory of granularity, which is inadequate for some domains, such as biology.
example of usage: a flame
example of usage: a forest fire
example of usage: a human being
example of usage: a hurricane
example of usage: a photon
example of usage: a puff of smoke
example of usage: a sea wave
example of usage: a tornado
example of usage: an aggregate of human beings.
example of usage: an energy wave
example of usage: an epidemic
has associated axiom(nl): every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
editor preferred term: material entity
example of usage: the undetached arm of a human being
imported from: BFO
imported from: ico.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

immaterial entity
type: Class
subclass of: independent continuant
subclass of: Restriction
  on property: has continuant part at all times that part exists
  all values from: Class
    complement of: material entity
subclass of: Restriction
  on property: has continuant part at some time
  all values from: Class
    complement of: material entity
subclass of: Restriction
  on property: has continuant part at all times that part exists
  all values from: immaterial entity
subclass of: Restriction
  on property: has continuant part at some time
  all values from: immaterial entity
editor note: BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10
BFO OWL specification label: immaterial
BFO CLIF specification label: ImmaterialEntity
imported from: bfo.owl
imported from: ogg.owl
imported from: vo.owl

zero-dimensional temporal region
type: Class
subclass of: temporal region
subclass of: Restriction
  on property: has proper occurrent part
  all values from: Nothing
has associated axiom(fol): (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001]
BFO CLIF specification label: ZeroDimensionalTemporalRegion
BFO OWL specification label: 0d-t-region
elucidation: A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])
example of usage: a temporal region that is occupied by a process boundary
example of usage: right now
alternative term: temporal instant.
example of usage: the moment at which a child is born
example of usage: the moment at which a finger is detached in an industrial accident
example of usage: the moment of death.
imported from: ogg.owl
imported from: vo.owl

gross anatomical part
type: Class
subclass of: material entity
definition: Anatomical structure that is part of a multicellular organism and is at the gross anatomical level, e.g. above the level of a cell. Included are portions of organism substances such as blood, multi-cell-part structures such as axon tracts, acellular anatomical structures such as hair, and organism subdivisions such as head. Excluded is the whole organism and more granular parts of the organism, such as atoms, molecules, macromolecular complexes and cells.
editor preferred term: gross anatomical part
imported from: caro.owl
imported from: obi.owl
imported from: vo.owl

urea
type: Class
subclass of: molecular entity
definition: A carbonyl group with two C-bound amine groups.
database_cross_reference: Beilstein:635724
has_related_synonym: CH4N2O
has_alternative_id: CHEBI:15292
id: CHEBI:16199
has_alternative_id: CHEBI:27218
has_alternative_id: CHEBI:46379
has_alternative_id: CHEBI:9888
has_related_synonym: Carbamide
database_cross_reference: ChemIDplus:57-13-6
database_cross_reference: CiteXplore:22770225
database_cross_reference: DrugBank:DB03904
has_related_synonym: E927b
database_cross_reference: Gmelin:1378
has_related_synonym: H2NC(O)NH2
database_cross_reference: HMDB:HMDB00294
has_related_synonym: Harnstoff
has_related_synonym: InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
has_related_synonym: InChIKey=XSQUKJJJFZCRTK-UHFFFAOYSA-N
database_cross_reference: KEGG COMPOUND:57-13-6
database_cross_reference: KEGG COMPOUND:C00086
database_cross_reference: KEGG DRUG:D00023
has_related_synonym: Karbamid
database_cross_reference: MetaCyc:UREA
has_related_synonym: NC(N)=O
database_cross_reference: NIST Chemistry WebBook:57-13-6
database_cross_reference: PDBeChem:URE
database_cross_reference: Reaxys:635724
database_cross_reference: UM-BBD:c0165
has_exact_synonym: UREA
has_exact_synonym: Urea
database_cross_reference: Wikipedia:Urea
has_related_synonym: carbamide
has_related_synonym: carbonyldiamide
has_obo_namespace: chebi_ontology
has_related_synonym: ur
has_exact_synonym: urea
has_related_synonym: uree
imported from: chebi.owl
imported from: vo.owl

formaldehyde
type: Class
subclass of: molecular entity
database_cross_reference: Beilstein:1209228
has_related_synonym: CH2O
has_alternative_id: CHEBI:14274
id: CHEBI:16842
has_alternative_id: CHEBI:24077
has_alternative_id: CHEBI:337763
has_alternative_id: CHEBI:5142
database_cross_reference: ChEMBL:7381846
database_cross_reference: ChemIDplus:50-00-0
database_cross_reference: CiteXplore:18837732
database_cross_reference: DrugBank:DB03843
has_exact_synonym: FORMALDEHYDE
has_related_synonym: FORMALIN
has_related_synonym: Formaldehyd
has_exact_synonym: Formaldehyde
has_related_synonym: Formalin
database_cross_reference: Gmelin:445
has_related_synonym: InChI=1S/CH2O/c1-2/h1H2
has_related_synonym: InChIKey=WSFSSNUMVMOOMR-UHFFFAOYSA-N
database_cross_reference: KEGG COMPOUND:50-00-0
database_cross_reference: KEGG COMPOUND:C00067
has_related_synonym: Methanal
has_related_synonym: Methylene oxide
database_cross_reference: NIST Chemistry WebBook:50-00-0
has_related_synonym: Oxomethane
has_related_synonym: Oxomethylene
database_cross_reference: PDBeChem:FLH
definition: The simplest aldehyde.
database_cross_reference: UM-BBD:c0122
database_cross_reference: Wikipedia:Formaldehyde
has_related_synonym: [H]C([H])=O
has_obo_namespace: chebi_ontology
has_exact_synonym: formaldehyde
imported from: chebi.owl
imported from: vo.owl

streptomycin
type: Class
subclass of: molecular entity
has_related_synonym: 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
definition: A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class
database_cross_reference: Beilstein:74498
has_related_synonym: C21H39N7O12
has_alternative_id: CHEBI:15119
id: CHEBI:17076
has_alternative_id: CHEBI:26784
has_alternative_id: CHEBI:45745
has_alternative_id: CHEBI:9284
database_cross_reference: ChemIDplus:57-92-1
database_cross_reference: CiteXplore:11228320
database_cross_reference: CiteXplore:11905029
database_cross_reference: CiteXplore:12118520
database_cross_reference: CiteXplore:13030054
database_cross_reference: CiteXplore:13116094
database_cross_reference: CiteXplore:13136149
database_cross_reference: CiteXplore:13596285
database_cross_reference: CiteXplore:13691614
database_cross_reference: CiteXplore:13985260
database_cross_reference: CiteXplore:13990247
database_cross_reference: CiteXplore:14623118
database_cross_reference: CiteXplore:14828344
database_cross_reference: CiteXplore:14852338
database_cross_reference: CiteXplore:14939639
database_cross_reference: CiteXplore:15081082
database_cross_reference: CiteXplore:15137533
database_cross_reference: CiteXplore:15207172
database_cross_reference: CiteXplore:15686853
database_cross_reference: CiteXplore:15736038
database_cross_reference: CiteXplore:16904706
database_cross_reference: CiteXplore:17105735
database_cross_reference: CiteXplore:17238915
database_cross_reference: CiteXplore:17429930
database_cross_reference: CiteXplore:18173084
database_cross_reference: CiteXplore:18916143
database_cross_reference: CiteXplore:19052412
database_cross_reference: CiteXplore:19335957
database_cross_reference: CiteXplore:21350946
database_cross_reference: CiteXplore:21362244
database_cross_reference: CiteXplore:21593257
database_cross_reference: CiteXplore:21937264
database_cross_reference: DrugBank:DB01082
has_related_synonym: InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1
has_related_synonym: InChIKey=UCSJYZPVAKXKNQ-HZYVHMACSA-N
database_cross_reference: KEGG COMPOUND:57-92-1
database_cross_reference: KEGG COMPOUND:C00413
database_cross_reference: KEGG DRUG:D08531
has_related_synonym: Kantrex
has_exact_synonym: N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
database_cross_reference: PDBeChem:SRY
database_cross_reference: Reaxys:74498
has_related_synonym: SM
has_exact_synonym: STREPTOMYCIN
database_cross_reference: Wikipedia:Streptomycin
has_related_synonym: [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
has_obo_namespace: chebi_ontology
has_related_synonym: streptomycin
imported from: chebi.owl
imported from: vo.owl

lactose
type: Class
subclass of: molecular entity
has_related_synonym: (+)-lactose
has_related_synonym: (Gal)1 (Glc)1
has_related_synonym: 1-beta-D-Galactopyranosyl-4-D-glucopyranose
has_related_synonym: 4-(beta-D-galactosido)-D-glucose
has_related_synonym: 4-O-beta-D-galactopyranosyl-D-glucose
definition: A disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form.
database_cross_reference: Beilstein:1292745
has_related_synonym: C12H22O11
has_alternative_id: CHEBI:10296
has_alternative_id: CHEBI:10380
has_alternative_id: CHEBI:14497
id: CHEBI:17716
has_alternative_id: CHEBI:22460
has_alternative_id: CHEBI:22760
has_alternative_id: CHEBI:25005
has_alternative_id: CHEBI:27755
has_alternative_id: CHEBI:613009
database_cross_reference: ChEMBL:19053747
database_cross_reference: ChemIDplus:63-42-3
database_cross_reference: CiteXplore:1292745
database_cross_reference: CiteXplore:17329833
database_cross_reference: CiteXplore:18300214
database_cross_reference: CiteXplore:19846069
database_cross_reference: CiteXplore:19913595
database_cross_reference: CiteXplore:20094999
database_cross_reference: CiteXplore:20503067
database_cross_reference: CiteXplore:20699559
database_cross_reference: CiteXplore:20873837
database_cross_reference: CiteXplore:20961532
database_cross_reference: CiteXplore:21403918
database_cross_reference: CiteXplore:2432147
database_cross_reference: CiteXplore:2456994
database_cross_reference: CiteXplore:6194884
database_cross_reference: CiteXplore:7574700
has_related_synonym: D-lactose
has_related_synonym: Galbeta1-4-Glc
database_cross_reference: Gmelin:882872
has_related_synonym: InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1
has_related_synonym: InChIKey=GUBGYTABKSRVRQ-QKKXKWKRSA-N
database_cross_reference: KEGG COMPOUND:C00243
database_cross_reference: KEGG GLYCAN:G10504
has_related_synonym: Lac
has_related_synonym: Laktobiose
has_related_synonym: Laktose
has_related_synonym: Milchzucker
database_cross_reference: NIST Chemistry WebBook:63-42-3
database_cross_reference: Reaxys:1292745
has_related_synonym: beta-D-Gal-(1->4)-D-Glc
has_related_synonym: beta-D-Galp-(1->4)-D-Glcp
has_exact_synonym: beta-D-galactopyranosyl-(1->4)-D-glucopyranose
has_related_synonym: beta-Gal1,4-Glc
has_obo_namespace: chebi_ontology
has_related_synonym: lactobiose
has_exact_synonym: lactose
has_related_synonym: milk sugar
imported from: chebi.owl
imported from: vo.owl

gentamycin
type: Class
subclass of: molecular entity
has_exact_synonym: 4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside
definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
has_alternative_id: CHEBI:14293
id: CHEBI:17833
has_alternative_id: CHEBI:24206
has_alternative_id: CHEBI:24212
has_alternative_id: CHEBI:5306
database_cross_reference: DrugBank:DB00798
has_related_synonym: Gentamicin
database_cross_reference: KEGG COMPOUND:1403-66-3
database_cross_reference: KEGG COMPOUND:C00505
has_obo_namespace: chebi_ontology
has_related_synonym: gentamicin
has_related_synonym: gentamycins
imported from: chebi.owl
imported from: vo.owl

sucrose
type: Class
subclass of: molecular entity
has_related_synonym: 1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside
database_cross_reference: Beilstein:90825
has_related_synonym: C12H22O11
has_alternative_id: CHEBI:15128
id: CHEBI:17992
has_alternative_id: CHEBI:26812
has_alternative_id: CHEBI:45795
has_alternative_id: CHEBI:9314
has_related_synonym: Cane sugar
database_cross_reference: ChemIDplus:57-50-1
database_cross_reference: CiteXplore:11021636
database_cross_reference: CiteXplore:11093712
database_cross_reference: CiteXplore:11111003
database_cross_reference: CiteXplore:12065720
database_cross_reference: CiteXplore:12706980
database_cross_reference: CiteXplore:13508893
database_cross_reference: CiteXplore:15291457
database_cross_reference: CiteXplore:15660210
database_cross_reference: CiteXplore:15792978
database_cross_reference: CiteXplore:15845855
database_cross_reference: CiteXplore:16228482
database_cross_reference: CiteXplore:16304615
database_cross_reference: CiteXplore:16313996
database_cross_reference: CiteXplore:16525719
database_cross_reference: CiteXplore:16660545
database_cross_reference: CiteXplore:16663947
database_cross_reference: CiteXplore:16665852
database_cross_reference: CiteXplore:17233733
database_cross_reference: CiteXplore:17439666
database_cross_reference: CiteXplore:17597061
database_cross_reference: CiteXplore:18625236
database_cross_reference: CiteXplore:19199566
database_cross_reference: CiteXplore:19726178
database_cross_reference: CiteXplore:21703290
database_cross_reference: CiteXplore:21972845
database_cross_reference: CiteXplore:22085755
database_cross_reference: CiteXplore:22311778
database_cross_reference: CiteXplore:22404833
database_cross_reference: CiteXplore:22751876
database_cross_reference: DrugBank:DB02772
database_cross_reference: Gmelin:97695
database_cross_reference: HMDB:HMDB00258
has_related_synonym: InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
has_related_synonym: InChIKey=CZMRCDWAGMRECN-UGDNZRGBSA-N
database_cross_reference: KEGG COMPOUND:57-50-1
database_cross_reference: KEGG COMPOUND:C00089
database_cross_reference: KEGG DRUG:D00025
database_cross_reference: KEGG GLYCAN:G00370
database_cross_reference: MetaCyc:SUCROSE
database_cross_reference: NIST Chemistry WebBook:57-50-1
database_cross_reference: PDBeChem:SUC
database_cross_reference: Reaxys:1435311
database_cross_reference: Reaxys:90825
has_exact_synonym: SUCROSE
has_related_synonym: Saccharose
has_related_synonym: Sacharose
has_exact_synonym: Sucrose
definition: Sucrose is a disaccharide formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose.
has_related_synonym: White sugar
database_cross_reference: Wikipedia:Sucrose
has_related_synonym: beta-D-Fruf-(2<->1)-alpha-D-Glcp
has_exact_synonym: beta-D-fructofuranosyl alpha-D-glucopyranoside
has_obo_namespace: chebi_ontology
has_related_synonym: sacarosa
has_related_synonym: table sugar
imported from: chebi.owl
imported from: vo.owl

molecular entity
type: Class
subclass of: material entity
definition: Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
id: CHEBI:23367
has_obo_namespace: chebi_ontology
has_related_synonym: entidad molecular
has_related_synonym: entidades moleculares
has_related_synonym: entite moleculaire
has_related_synonym: molecular entities
has_exact_synonym: molecular entity
has_related_synonym: molekulare Entitaet
imported from: chebi.owl
imported from: vo.owl

aspartame
type: Class
subclass of: molecular entity
has_related_synonym: 1-methyl N-L-alpha-aspartyl-L-phenylalanate
has_related_synonym: 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester
has_related_synonym: 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid
definition: A dipeptide that has formula C14H18N2O5.
has_related_synonym: Asp-phe-ome
has_exact_synonym: Aspartame
has_related_synonym: Aspartylphenylalanine methyl ester
database_cross_reference: Beilstein:2223850
has_related_synonym: C14H18N2O5
id: CHEBI:2877
database_cross_reference: ChemIDplus:22839-47-0
database_cross_reference: DrugBank:DB00168
has_related_synonym: InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
has_related_synonym: InChIKey=IAOZJIPTCAWIRG-QWRGUYRKSA-N
database_cross_reference: KEGG COMPOUND:C11045
database_cross_reference: KEGG DRUG:D02381
has_related_synonym: L-Aspartyl-L-phenylalanine methyl ester
has_related_synonym: aspartam
has_related_synonym: aspartame
has_related_synonym: aspartamo
has_related_synonym: aspartamum
has_obo_namespace: chebi_ontology
has_exact_synonym: methyl L-alpha-aspartyl-L-phenylalaninate
imported from: chebi.owl
imported from: vo.owl

glucitol
type: Class
subclass of: molecular entity
database_cross_reference: Beilstein:1721909
has_related_synonym: C6H14O6
has_alternative_id: CHEBI:15093
has_alternative_id: CHEBI:26724
has_alternative_id: CHEBI:26726
id: CHEBI:30911
has_alternative_id: CHEBI:33795
has_alternative_id: CHEBI:33796
has_alternative_id: CHEBI:9201
database_cross_reference: Gmelin:83165
has_related_synonym: Sorbitol
has_obo_namespace: chebi_ontology
has_exact_synonym: glucitol
has_related_synonym: gulitol
has_related_synonym: rel-(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
has_related_synonym: sorbitol
imported from: chebi.owl
imported from: vo.owl

dextran
type: Class
subclass of: molecular entity
has_related_synonym: (C12H20O10)n
definition: A (1->6)-alpha-D-glucan which has extra branching consisting of (1->2), (1->3) or (1->4) linkages.
id: CHEBI:52071
database_cross_reference: ChemIDplus:9004-54-0
database_cross_reference: CiteXplore:8154046
has_related_synonym: Dextran 40
has_related_synonym: Dextran 70
database_cross_reference: KEGG DRUG:D00060
has_obo_namespace: chebi_ontology
has_related_synonym: dextran
has_related_synonym: dextrano
has_related_synonym: dextrans
has_related_synonym: dextranum
imported from: chebi.owl
imported from: vo.owl

monosodium glutamate
type: Class
subclass of: molecular entity
definition: An organic sodium salt that is the monosodium salt of glutamic acid.
has_related_synonym: C5H8NNaO4
id: CHEBI:64220
database_cross_reference: CiteXplore:22293291
has_related_synonym: InChI=1S/C5H9NO4.Na/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);/q;+1/p-1
has_related_synonym: InChIKey=LPUQAYUQRXPFSQ-UHFFFAOYSA-M
has_related_synonym: MSG
database_cross_reference: Reaxys:17003240
has_related_synonym: [Na+].[NH3+]C(CCC([O-])=O)C([O-])=O
has_obo_namespace: chebi_ontology
has_related_synonym: sodium 2-ammoniopentanedioate
has_exact_synonym: sodium 2-azaniumylpentanedioate
has_related_synonym: sodium glutamate
imported from: chebi.owl
imported from: vo.owl

neomycin
type: Class
subclass of: molecular entity
definition: A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections.
id: CHEBI:7507
database_cross_reference: DrugBank:DB00994
database_cross_reference: KEGG COMPOUND:C00384
has_exact_synonym: Neomycin
has_obo_namespace: chebi_ontology
imported from: chebi.owl
imported from: vo.owl

thimerosal
type: Class
subclass of: molecular entity
definition: An organomercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.
database_cross_reference: Beilstein:8169555
has_related_synonym: C9H9HgNaO2S
has_related_synonym: C9H9HgO2S.Na
id: CHEBI:9546
database_cross_reference: ChemIDplus:54-64-8
database_cross_reference: CiteXplore:18837732
database_cross_reference: CiteXplore:21616561
database_cross_reference: Gmelin:1677155
has_related_synonym: InChI=1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
has_related_synonym: InChIKey=RTKIYNMVFMVABJ-UHFFFAOYSA-L
database_cross_reference: KEGG COMPOUND:C08044
has_related_synonym: Merthiolate
has_exact_synonym: Thimerosal
has_related_synonym: Thiomersal
has_related_synonym: [(o-carboxyphenyl)thio]ethylmercury sodium salt
has_related_synonym: [Na+].CC[Hg]Sc1ccccc1C([O-])=O
has_obo_namespace: chebi_ontology
has_related_synonym: ethyl(2-mercaptobenzoato-S)mercury sodium salt
has_related_synonym: ethylmercurithiosalicylate sodium
has_related_synonym: mercurothiolate
has_related_synonym: o-(ethylmercurithio)benzoic acid sodium salt
has_exact_synonym: sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercurate(1-)
has_exact_synonym: sodium ethyl[2-(sulfanyl-kappaS)benzoato(2-)]mercurate(1-)
has_related_synonym: sodium ethylmercurithiosalicylate
has_related_synonym: thiomersalate
imported from: chebi.owl
imported from: vo.owl

cardiomyopathy
type: Class
subclass of: heart disease
creation date: 2012-01-03T02:54:11Z
definition: A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.
has_exact_synonym: Cardiomyopathies
id: DOID:0050700
database_cross_reference: ICD10CM:I42
database_cross_reference: ICD10CM:I42.9
database_cross_reference: ICD10CM:I51.5
database_cross_reference: ICD9CM:425
database_cross_reference: ICD9CM:425.9
database_cross_reference: MSH:D009202
comment: MSH:D009202 added from NeuroDevNet [WAK].
database_cross_reference: NCI:C34830
database_cross_reference: NCI:C53654
database_cross_reference: SNOMEDCT_US_2015_03_01:155351008
database_cross_reference: SNOMEDCT_US_2015_03_01:155353006
database_cross_reference: SNOMEDCT_US_2015_03_01:195035002
database_cross_reference: SNOMEDCT_US_2015_03_01:195037005
database_cross_reference: SNOMEDCT_US_2015_03_01:20072003
database_cross_reference: SNOMEDCT_US_2015_03_01:266244008
database_cross_reference: SNOMEDCT_US_2015_03_01:266301006
database_cross_reference: SNOMEDCT_US_2015_03_01:57809008
database_cross_reference: SNOMEDCT_US_2015_03_01:85898001
database_cross_reference: SNOMEDCT_US_2015_03_01:89461002
database_cross_reference: SNOMEDCT_US_2015_03_01:89600009
database_cross_reference: UMLS_CUI:C0033141
database_cross_reference: UMLS_CUI:C0036529
database_cross_reference: UMLS_CUI:C0878544
has_obo_namespace: disease_ontology
created by: lschriml
imported from: doid.owl

lymphoma
type: Class
subclass of: cancer
definition: A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.
id: DOID:0060058
has_alternative_id: DOID:1033
has_alternative_id: DOID:353
database_cross_reference: ICD10CM:C85.9
database_cross_reference: MSH:D008223
database_cross_reference: NCI:C3208
database_cross_reference: NCI:C7065
database_cross_reference: SNOMEDCT_US_2015_03_01:115244002
database_cross_reference: SNOMEDCT_US_2015_03_01:118600007
database_cross_reference: SNOMEDCT_US_2015_03_01:134218000
database_cross_reference: SNOMEDCT_US_2015_03_01:188676008
database_cross_reference: SNOMEDCT_US_2015_03_01:188694002
database_cross_reference: SNOMEDCT_US_2015_03_01:188695001
database_cross_reference: SNOMEDCT_US_2015_03_01:188704004
database_cross_reference: SNOMEDCT_US_2015_03_01:189959002
database_cross_reference: SNOMEDCT_US_2015_03_01:189965002
database_cross_reference: SNOMEDCT_US_2015_03_01:21964009
database_cross_reference: SNOMEDCT_US_2015_03_01:269627002
database_cross_reference: SNOMEDCT_US_2015_03_01:414628006
database_cross_reference: UMLS_CUI:C0024299
database_cross_reference: UMLS_CUI:C0598798
has_obo_namespace: disease_ontology
has_exact_synonym: lymphoid cancer
imported from: doid.owl
in_subset: DO cancer slim

heart disease
type: Class
subclass of: disease
definition: A cardiovascular system disease that involves the heart.
id: DOID:114
database_cross_reference: ICD10CM:I51.9
database_cross_reference: ICD9CM:429.9
database_cross_reference: MSH:D006331
database_cross_reference: NCI:C3079
database_cross_reference: SNOMEDCT_US_2015_03_01:155263000
database_cross_reference: SNOMEDCT_US_2015_03_01:194707003
database_cross_reference: SNOMEDCT_US_2015_03_01:195152001
database_cross_reference: SNOMEDCT_US_2015_03_01:266275004
database_cross_reference: SNOMEDCT_US_2015_03_01:266311004
database_cross_reference: SNOMEDCT_US_2015_03_01:56265001
database_cross_reference: UMLS_CUI:C0018799
has_obo_namespace: disease_ontology
imported from: doid.owl

hypersensitivity reaction type I disease
type: Class
subclass of: disease
definition: An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.
id: DOID:1205
database_cross_reference: ICD10CM:T78.40
database_cross_reference: MSH:D006967
database_cross_reference: NCI:C3114
database_cross_reference: SNOMEDCT_US_2015_03_01:106190000
database_cross_reference: SNOMEDCT_US_2015_03_01:127072000
database_cross_reference: SNOMEDCT_US_2015_03_01:157754004
database_cross_reference: SNOMEDCT_US_2015_03_01:157758001
database_cross_reference: SNOMEDCT_US_2015_03_01:212998004
database_cross_reference: SNOMEDCT_US_2015_03_01:212999007
database_cross_reference: SNOMEDCT_US_2015_03_01:21957007
database_cross_reference: SNOMEDCT_US_2015_03_01:257550005
database_cross_reference: SNOMEDCT_US_2015_03_01:269284003
database_cross_reference: SNOMEDCT_US_2015_03_01:269432007
database_cross_reference: SNOMEDCT_US_2015_03_01:274211000
database_cross_reference: SNOMEDCT_US_2015_03_01:282092005
database_cross_reference: SNOMEDCT_US_2015_03_01:418168000
database_cross_reference: SNOMEDCT_US_2015_03_01:418634005
database_cross_reference: SNOMEDCT_US_2015_03_01:418925002
database_cross_reference: SNOMEDCT_US_2015_03_01:421668005
database_cross_reference: SNOMEDCT_US_2015_03_01:421961002
database_cross_reference: SNOMEDCT_US_2015_03_01:91232002
database_cross_reference: UMLS_CUI:C0020517
has_exact_synonym: allergy
has_obo_namespace: disease_ontology
has_exact_synonym: hypersensitivity
imported from: doid.owl

leukemia
type: Class
subclass of: cancer
definition: A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.
id: DOID:1240
has_alternative_id: DOID:9145
database_cross_reference: ICD10CM:C95
database_cross_reference: ICD10CM:C95.9
database_cross_reference: ICD10CM:C95.90
database_cross_reference: ICD9CM:208
database_cross_reference: ICD9CM:208.9
database_cross_reference: MSH:D007938
database_cross_reference: NCI:C3161
database_cross_reference: SNOMEDCT_US_2015_03_01:154598008
database_cross_reference: SNOMEDCT_US_2015_03_01:188762002
database_cross_reference: SNOMEDCT_US_2015_03_01:188767008
database_cross_reference: SNOMEDCT_US_2015_03_01:190024009
database_cross_reference: SNOMEDCT_US_2015_03_01:190025005
database_cross_reference: SNOMEDCT_US_2015_03_01:190029004
database_cross_reference: SNOMEDCT_US_2015_03_01:190071003
database_cross_reference: SNOMEDCT_US_2015_03_01:255049003
database_cross_reference: SNOMEDCT_US_2015_03_01:87163000
database_cross_reference: SNOMEDCT_US_2015_03_01:93143009
database_cross_reference: UMLS_CUI:C0023418
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: DO cancer slim

Guillain-Barre syndrome
type: Class
subclass of: hypersensitivity reaction type II disease
definition: An autoimmune disease of peripheral nervous system that causes body's immune system to attack part of the peripheral nervous system.
id: DOID:12842
has_exact_synonym: Guillain-Barre syndrome (disorder)
database_cross_reference: ICD10CM:G61.0
database_cross_reference: ICD9CM:357.0
has_exact_synonym: Infectious neuronitis (disorder)
database_cross_reference: MSH:D020275
database_cross_reference: NCI:C26790
comment: OMIM mapping confirmed by DO. [SN].
database_cross_reference: OMIM:139393
has_exact_synonym: Post-infectious polyneuritis (disorder)
has_exact_synonym: Postinfectious polyneuritis
database_cross_reference: SNOMEDCT_US_2015_03_01:128085000
database_cross_reference: SNOMEDCT_US_2015_03_01:129131007
database_cross_reference: SNOMEDCT_US_2015_03_01:155082001
database_cross_reference: SNOMEDCT_US_2015_03_01:193173004
database_cross_reference: SNOMEDCT_US_2015_03_01:193174005
database_cross_reference: SNOMEDCT_US_2015_03_01:193176007
database_cross_reference: SNOMEDCT_US_2015_03_01:267707000
database_cross_reference: SNOMEDCT_US_2015_03_01:40956001
database_cross_reference: UMLS_CUI:C0018378
has_exact_synonym: acute Infective Polyneuritis
has_exact_synonym: acute inf. polyneuritis
has_exact_synonym: acute infective polyneuritis
has_exact_synonym: acute infective polyneuritis (disorder)
has_exact_synonym: acute infective polyneuritis NOS (disorder)
has_exact_synonym: acute postinfectious polyneuropathy
has_obo_namespace: disease_ontology
imported from: doid.owl

diarrhea
type: Class
subclass of: disease
definition: A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea.
has_alternative_id: DOID:0050006
id: DOID:13250
database_cross_reference: ICD9CM:009.2
database_cross_reference: MSH:D004403
database_cross_reference: SNOMEDCT_US_2015_03_01:111939009
database_cross_reference: SNOMEDCT_US_2015_03_01:154268000
database_cross_reference: SNOMEDCT_US_2015_03_01:154279005
database_cross_reference: SNOMEDCT_US_2015_03_01:186165000
database_cross_reference: SNOMEDCT_US_2015_03_01:186167008
database_cross_reference: SNOMEDCT_US_2015_03_01:19213003
database_cross_reference: SNOMEDCT_US_2015_03_01:236076004
database_cross_reference: SNOMEDCT_US_2015_03_01:266173000
database_cross_reference: SNOMEDCT_US_2015_03_01:266180003
database_cross_reference: UMLS_CUI:C0013369
has_related_synonym: diarrhea of presumed infectious origin
has_related_synonym: diarrhoea
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: GOLD

thrombocytopenia
type: Class
subclass of: disease
definition: A blood platelet disease characterized by low a platelet count in the blood.
id: DOID:1588
database_cross_reference: ICD10CM:D69.6
database_cross_reference: ICD9CM:287.5
database_cross_reference: MSH:D013921
database_cross_reference: NCI:C3408
database_cross_reference: OMIM:188000
database_cross_reference: OMIM:273900
database_cross_reference: OMIM:300367
database_cross_reference: OMIM:313900
database_cross_reference: OMIM:612004
database_cross_reference: ORDO:852
database_cross_reference: SNOMEDCT_US_2015_03_01:142969008
database_cross_reference: SNOMEDCT_US_2015_03_01:154827000
database_cross_reference: SNOMEDCT_US_2015_03_01:165556002
database_cross_reference: SNOMEDCT_US_2015_03_01:191326009
database_cross_reference: SNOMEDCT_US_2015_03_01:302215000
database_cross_reference: SNOMEDCT_US_2015_03_01:415116008
database_cross_reference: SNOMEDCT_US_2015_03_01:70786006
database_cross_reference: UMLS_CUI:C0040034
comment: Xref MGI.
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: DO MGI slim

cancer
type: Class
subclass of: disposition
subclass of: disease
definition: A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
id: DOID:162
database_cross_reference: ICD10CM:C80
database_cross_reference: ICD10CM:C80.1
database_cross_reference: ICD9CM:199
database_cross_reference: ICD9CM:239.4
database_cross_reference: MSH:D009369
database_cross_reference: NCI:C9305
database_cross_reference: SNOMEDCT_2010_1_31:189535002
database_cross_reference: SNOMEDCT_US_2015_03_01:154432008
database_cross_reference: SNOMEDCT_US_2015_03_01:154433003
database_cross_reference: SNOMEDCT_US_2015_03_01:154577008
database_cross_reference: SNOMEDCT_US_2015_03_01:187597000
database_cross_reference: SNOMEDCT_US_2015_03_01:188475001
database_cross_reference: SNOMEDCT_US_2015_03_01:188482002
database_cross_reference: SNOMEDCT_US_2015_03_01:190150006
database_cross_reference: SNOMEDCT_US_2015_03_01:269513004
database_cross_reference: SNOMEDCT_US_2015_03_01:269623003
database_cross_reference: SNOMEDCT_US_2015_03_01:269626006
database_cross_reference: SNOMEDCT_US_2015_03_01:269634000
database_cross_reference: SNOMEDCT_US_2015_03_01:363346000
database_cross_reference: SNOMEDCT_US_2015_03_01:38807002
database_cross_reference: UMLS_CUI:C0006826
database_cross_reference: UMLS_CUI:C0027639
comment: Updating out dated UMLS CUI.
has_obo_namespace: disease_ontology
has_exact_synonym: malignant neoplasm
has_exact_synonym: malignant tumor
has_exact_synonym: primary cancer
imported from: doid.owl
imported from: vo.owl

transient cerebral ischemia
type: Class
subclass of: disease
id: DOID:224
has_alternative_id: DOID:2315
database_cross_reference: ICD10CM:G45.9
database_cross_reference: ICD9CM:435.8
database_cross_reference: MSH:D002546
database_cross_reference: NCI:C50781
database_cross_reference: SNOMEDCT_US_2015_03_01:155404005
database_cross_reference: SNOMEDCT_US_2015_03_01:195196001
database_cross_reference: SNOMEDCT_US_2015_03_01:195207009
database_cross_reference: SNOMEDCT_US_2015_03_01:266257000
database_cross_reference: SNOMEDCT_US_2015_03_01:266314007
database_cross_reference: SNOMEDCT_US_2015_03_01:313242003
database_cross_reference: SNOMEDCT_US_2015_03_01:38609002
has_exact_synonym: TIA
has_exact_synonym: TIA - Transient ischaemic attack
has_exact_synonym: TRANSIENT ISCHEMIC ATTACK
has_exact_synonym: Transient cerebral ischaemia
has_exact_synonym: Transient cerebral ischaemia NOS
has_exact_synonym: Transient cerebral ischemia (disorder) [Ambiguous]
has_exact_synonym: Transient ischemic attacks (disorder)
database_cross_reference: UMLS_CUI:C0007787
database_cross_reference: UMLS_CUI:C0155728
has_obo_namespace: disease_ontology
has_exact_synonym: transient ischemic attack
imported from: doid.owl

anemia
type: Class
subclass of: disease
definition: A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.
id: DOID:2355
database_cross_reference: EFO:0004272
database_cross_reference: ICD10CM:D64.9
database_cross_reference: ICD9CM:285.9
database_cross_reference: MSH:D000740
database_cross_reference: NCI:C2869
comment: PRISM.
database_cross_reference: SNOMEDCT_US_2015_03_01:154786001
database_cross_reference: SNOMEDCT_US_2015_03_01:154812000
database_cross_reference: SNOMEDCT_US_2015_03_01:191277004
database_cross_reference: SNOMEDCT_US_2015_03_01:267531008
database_cross_reference: SNOMEDCT_US_2015_03_01:271737000
database_cross_reference: SNOMEDCT_US_2015_03_01:64593003
database_cross_reference: UMLS_CUI:C0002871
has_exact_synonym: anaemia
has_obo_namespace: disease_ontology
imported from: doid.owl

agammaglobulinemia
type: Class
subclass of: disease
definition: A B cell deficiency that is caused by a reduction in all types of gamma globulins.
id: DOID:2583
has_alternative_id: DOID:618
database_cross_reference: ICD10CM:D80.1
database_cross_reference: ICD9CM:279.00
has_exact_synonym: IGHM
database_cross_reference: MSH:D000361
database_cross_reference: NCI:C26931
comment: OMIM mapping confirmed by DO. [SN].
database_cross_reference: OMIM:601495
database_cross_reference: OMIM:612692
database_cross_reference: OMIM:613500
database_cross_reference: OMIM:613501
database_cross_reference: OMIM:613502
database_cross_reference: OMIM:613506
database_cross_reference: OMIM:615214
database_cross_reference: SNOMEDCT_US_2015_03_01:119249001
database_cross_reference: SNOMEDCT_US_2015_03_01:119250001
database_cross_reference: SNOMEDCT_US_2015_03_01:190977001
database_cross_reference: SNOMEDCT_US_2015_03_01:190978006
database_cross_reference: SNOMEDCT_US_2015_03_01:267512002
database_cross_reference: SNOMEDCT_US_2015_03_01:81282009
database_cross_reference: UMLS_CUI:C0001768
database_cross_reference: UMLS_CUI:C0086438
has_obo_namespace: disease_ontology
has_exact_synonym: hypogammaglobulinemia
has_exact_synonym: mu heavy chain deficiency
imported from: doid.owl

dermatitis
type: Class
subclass of: disease
definition: A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.
id: DOID:2723
has_alternative_id: DOID:8614
has_alternative_id: DOID:8917
database_cross_reference: ICD10CM:L30.9
database_cross_reference: MSH:D003872
database_cross_reference: NCI:C2983
database_cross_reference: SNOMEDCT_US_2015_03_01:156358005
database_cross_reference: SNOMEDCT_US_2015_03_01:156388001
database_cross_reference: SNOMEDCT_US_2015_03_01:182782007
database_cross_reference: SNOMEDCT_US_2015_03_01:200884006
database_cross_reference: SNOMEDCT_US_2015_03_01:238538009
database_cross_reference: SNOMEDCT_US_2015_03_01:267847004
database_cross_reference: SNOMEDCT_US_2015_03_01:267856007
database_cross_reference: SNOMEDCT_US_2015_03_01:43116000
database_cross_reference: SNOMEDCT_US_2015_03_01:4979002
database_cross_reference: UMLS_CUI:C0011603
has_obo_namespace: disease_ontology
has_exact_synonym: eczema
has_exact_synonym: skin inflammation
imported from: doid.owl

keratosis follicularis
type: Class
subclass of: disease
has_exact_synonym: DARIER-WHITE DISEASE
id: DOID:2734
has_exact_synonym: Darier's disease
database_cross_reference: ICD10CM:E50.8
has_exact_synonym: Keratosis follicularis (disorder)
database_cross_reference: MSH:D007644
database_cross_reference: NCI:C84665
comment: OMIM mapping confirmed by DO. [SN].
database_cross_reference: OMIM:124200
database_cross_reference: SNOMEDCT_US_2015_03_01:157017000
database_cross_reference: SNOMEDCT_US_2015_03_01:205582000
database_cross_reference: SNOMEDCT_US_2015_03_01:240633005
database_cross_reference: SNOMEDCT_US_2015_03_01:268355000
database_cross_reference: SNOMEDCT_US_2015_03_01:48611009
database_cross_reference: UMLS_CUI:C0022595
has_obo_namespace: disease_ontology
imported from: doid.owl

asthma
type: Class
subclass of: disease
definition: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.
has_alternative_id: DOID:12703
has_alternative_id: DOID:13829
has_alternative_id: DOID:13830
has_alternative_id: DOID:2840
id: DOID:2841
has_alternative_id: DOID:5783
database_cross_reference: EFO:0000270
has_exact_synonym: Exercise induced asthma
database_cross_reference: ICD10CM:J45
database_cross_reference: ICD10CM:J45.90
database_cross_reference: ICD10CM:J45.909
database_cross_reference: ICD9CM:493
database_cross_reference: ICD9CM:493.9
database_cross_reference: KEGG:05310
database_cross_reference: MSH:D001249
database_cross_reference: NCI:C28397
database_cross_reference: OMIM:600807
database_cross_reference: SNOMEDCT_US_2015_03_01:155574008
database_cross_reference: SNOMEDCT_US_2015_03_01:155579003
database_cross_reference: SNOMEDCT_US_2015_03_01:187687003
database_cross_reference: SNOMEDCT_US_2015_03_01:195967001
database_cross_reference: SNOMEDCT_US_2015_03_01:195979001
database_cross_reference: SNOMEDCT_US_2015_03_01:195983001
database_cross_reference: SNOMEDCT_US_2015_03_01:21341004
database_cross_reference: SNOMEDCT_US_2015_03_01:266365004
database_cross_reference: SNOMEDCT_US_2015_03_01:266398009
database_cross_reference: SNOMEDCT_US_2015_03_01:278517007
database_cross_reference: UMLS_CUI:C0004096
comment: Xref MGI.
has_exact_synonym: bronchial hyperreactivity
has_exact_synonym: chronic obstructive asthma
has_exact_synonym: chronic obstructive asthma with acute exacerbation
has_exact_synonym: chronic obstructive asthma with status asthmaticus
has_obo_namespace: disease_ontology
has_exact_synonym: exercise-induced asthma
imported from: doid.owl
in_subset: DO MGI slim

food allergy
type: Class
subclass of: hypersensitivity reaction type I disease
definition: A hypersensitivity reaction type I disease that is an abnormal response to a food, triggered by the body's immune system.
id: DOID:3044
database_cross_reference: MSH:D005512
database_cross_reference: SNOMEDCT_US_2015_03_01:157801005
database_cross_reference: SNOMEDCT_US_2015_03_01:213018006
database_cross_reference: SNOMEDCT_US_2015_03_01:414285001
database_cross_reference: SNOMEDCT_US_2015_03_01:52332009
database_cross_reference: UMLS_CUI:C0016470
has_obo_namespace: disease_ontology
has_exact_synonym: food hypersensitivity
imported from: doid.owl

chronic obstructive pulmonary disease
type: Class
subclass of: lung disease
has_exact_synonym: COLD (chronic obstructive lung disease)
has_exact_synonym: COPD
has_alternative_id: DOID:11500
id: DOID:3083
has_alternative_id: DOID:6144
database_cross_reference: EFO:0000341
database_cross_reference: ICD10CM:J44.9
database_cross_reference: MSH:D029424
database_cross_reference: NCI:C3199
database_cross_reference: SNOMEDCT_US_2015_03_01:10169006
database_cross_reference: SNOMEDCT_US_2015_03_01:13645005
database_cross_reference: SNOMEDCT_US_2015_03_01:155565006
database_cross_reference: SNOMEDCT_US_2015_03_01:155569000
database_cross_reference: SNOMEDCT_US_2015_03_01:155585005
database_cross_reference: SNOMEDCT_US_2015_03_01:155617000
database_cross_reference: SNOMEDCT_US_2015_03_01:195935004
database_cross_reference: SNOMEDCT_US_2015_03_01:195948000
database_cross_reference: SNOMEDCT_US_2015_03_01:196003006
database_cross_reference: SNOMEDCT_US_2015_03_01:413846005
database_cross_reference: UMLS_CUI:C0024117
has_exact_synonym: chronic obstructive airway disease
has_exact_synonym: chronic obstructive lung disease
has_obo_namespace: disease_ontology
imported from: doid.owl

thymoma
type: Class
subclass of: cancer
definition: A thymus cancer that derives_from epithelial cells located_in the thymus. The tumor cells in a thymoma look similar to the normal cells of the thymus, grow slowly, and rarely spread beyond the thymus.
id: DOID:3275
database_cross_reference: MSH:D013945
database_cross_reference: NCI:C3411
database_cross_reference: SNOMEDCT_US_2015_03_01:128856005
database_cross_reference: SNOMEDCT_US_2015_03_01:189721001
database_cross_reference: SNOMEDCT_US_2015_03_01:444231005
database_cross_reference: UMLS_CUI:C0040100
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: DO cancer slim

disease
type: Class
subclass of: disposition
definition: A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
id: DOID:4
database_cross_reference: MSH:D004194
database_cross_reference: NCI:C2991
database_cross_reference: SNOMEDCT_US_2015_03_01:64572001
database_cross_reference: UMLS_CUI:C0012634
has_obo_namespace: disease_ontology
imported from: doid.owl

liver disease
type: Class
subclass of: disease
has_alternative_id: DOID:2164
has_alternative_id: DOID:2165
id: DOID:409
has_alternative_id: DOID:46
database_cross_reference: ICD10CM:K70-K77
database_cross_reference: ICD10CM:K76.9
database_cross_reference: ICD9CM:573.9
database_cross_reference: MSH:D008107
database_cross_reference: NCI:C3196
database_cross_reference: SNOMEDCT_US_2015_03_01:155807008
database_cross_reference: SNOMEDCT_US_2015_03_01:155817003
database_cross_reference: SNOMEDCT_US_2015_03_01:155822003
database_cross_reference: SNOMEDCT_US_2015_03_01:197375001
database_cross_reference: SNOMEDCT_US_2015_03_01:197551000
database_cross_reference: SNOMEDCT_US_2015_03_01:235856003
database_cross_reference: SNOMEDCT_US_2015_03_01:266535008
database_cross_reference: SNOMEDCT_US_2015_03_01:62857009
database_cross_reference: UMLS_CUI:C0023895
has_obo_namespace: disease_ontology
has_exact_synonym: disorder of liver (disorder)
has_exact_synonym: hepatic disorder
imported from: doid.owl

hypersensitivity reaction type II disease
type: Class
subclass of: disease
definition: An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.
id: DOID:417
database_cross_reference: ICD9CM:720
database_cross_reference: UMLS_CUI:C0003089
comment: Xref MGI.
has_exact_synonym: autoimmune disease
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: DO MGI slim

egg allergy
type: Class
subclass of: food allergy
definition: A food allergy that is an allergy or hypersensitivity to dietary substances from the yolk or whites of eggs, causing an overreaction of the immune system which may lead to severe physical symptoms.
has_exact_synonym: Allergy to eggs (disorder)
id: DOID:4377
has_exact_synonym: Egg allergy
database_cross_reference: MSH:D021181
database_cross_reference: SNOMEDCT_US_2015_03_01:157802003
database_cross_reference: SNOMEDCT_US_2015_03_01:213019003
database_cross_reference: SNOMEDCT_US_2015_03_01:91930004
database_cross_reference: UMLS_CUI:C0559469
has_obo_namespace: disease_ontology
imported from: doid.owl

thymus gland disease
type: Class
subclass of: disease
has_alternative_id: DOID:11024
id: DOID:533
database_cross_reference: ICD10CM:E32
database_cross_reference: ICD10CM:E32.9
database_cross_reference: ICD9CM:254
database_cross_reference: ICD9CM:254.9
database_cross_reference: NCI:C26962
database_cross_reference: SNOMEDCT_US_2015_03_01:154703006
database_cross_reference: SNOMEDCT_US_2015_03_01:190500009
database_cross_reference: SNOMEDCT_US_2015_03_01:20673009
database_cross_reference: SNOMEDCT_US_2015_03_01:267482009
database_cross_reference: UMLS_CUI:C0154199
has_exact_synonym: disease of thymus gland
has_obo_namespace: disease_ontology
imported from: doid.owl

kidney disease
type: Class
subclass of: disease
definition: A urinary system disease that is located_in the kidney.
id: DOID:557
database_cross_reference: EFO:0003086
database_cross_reference: ICD10CM:N08
database_cross_reference: ICD10CM:N28.9
database_cross_reference: MSH:D007674
database_cross_reference: NCI:C3149
database_cross_reference: NCI:C34843
database_cross_reference: SNOMEDCT_US_2015_03_01:155871008
database_cross_reference: SNOMEDCT_US_2015_03_01:266612003
database_cross_reference: SNOMEDCT_US_2015_03_01:266624005
database_cross_reference: SNOMEDCT_US_2015_03_01:266627003
database_cross_reference: SNOMEDCT_US_2015_03_01:274108006
database_cross_reference: SNOMEDCT_US_2015_03_01:90708001
database_cross_reference: UMLS_CUI:C0022658
has_obo_namespace: disease_ontology
has_exact_synonym: nephropathy
imported from: doid.owl

myocardial infarction
type: Class
subclass of: disease
definition: A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.
id: DOID:5844
database_cross_reference: EFO:0000612
database_cross_reference: ICD10CM:I21
database_cross_reference: ICD10CM:I22
database_cross_reference: MSH:D009203
has_exact_synonym: Myocardial infarct
database_cross_reference: NCI:C27996
database_cross_reference: OMIM:608446
database_cross_reference: OMIM:608557
database_cross_reference: SNOMEDCT_US_2015_03_01:155304006
database_cross_reference: SNOMEDCT_US_2015_03_01:194796000
database_cross_reference: SNOMEDCT_US_2015_03_01:22298006
database_cross_reference: SNOMEDCT_US_2015_03_01:233824008
database_cross_reference: SNOMEDCT_US_2015_03_01:266288001
database_cross_reference: SNOMEDCT_US_2015_03_01:66514008
database_cross_reference: UMLS_CUI:C0027051
comment: Xref MGI.
has_obo_namespace: disease_ontology
has_exact_synonym: heart attack
imported from: doid.owl
in_subset: DO MGI slim

congestive heart failure
type: Class
subclass of: heart disease
definition: A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.
has_exact_synonym: CHF
has_exact_synonym: Cardiac Failure Congestive
has_exact_synonym: Congestive heart disease
has_alternative_id: DOID:395
id: DOID:6000
database_cross_reference: ICD10CM:I50
database_cross_reference: ICD10CM:I50.9
database_cross_reference: ICD9CM:428
database_cross_reference: ICD9CM:428.0
database_cross_reference: ICD9CM:428.9
database_cross_reference: MSH:D006333
database_cross_reference: NCI:C3080
database_cross_reference: NCI:C50577
database_cross_reference: SNOMEDCT_US_2015_03_01:155374007
database_cross_reference: SNOMEDCT_US_2015_03_01:155375008
database_cross_reference: SNOMEDCT_US_2015_03_01:155377000
database_cross_reference: SNOMEDCT_US_2015_03_01:195108009
database_cross_reference: SNOMEDCT_US_2015_03_01:195117009
database_cross_reference: SNOMEDCT_US_2015_03_01:266248006
database_cross_reference: SNOMEDCT_US_2015_03_01:266308000
database_cross_reference: SNOMEDCT_US_2015_03_01:42343007
database_cross_reference: SNOMEDCT_US_2015_03_01:84114007
database_cross_reference: UMLS_CUI:C0018801
database_cross_reference: UMLS_CUI:C0018802
has_exact_synonym: Weak heart
has_obo_namespace: disease_ontology
imported from: doid.owl

acquired immunodeficiency syndrome
type: Class
subclass of: disease
definition: A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per µL of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.
has_exact_synonym: AIDS
id: DOID:635
database_cross_reference: EFO:0000765
database_cross_reference: ICD10CM:B20
database_cross_reference: MSH:D000163
database_cross_reference: NCI:C2851
database_cross_reference: OMIM:609423
database_cross_reference: SNOMEDCT_US_2015_03_01:186705005
database_cross_reference: SNOMEDCT_US_2015_03_01:186715004
database_cross_reference: SNOMEDCT_US_2015_03_01:234644008
database_cross_reference: SNOMEDCT_US_2015_03_01:266201009
database_cross_reference: SNOMEDCT_US_2015_03_01:62479008
database_cross_reference: UMLS_CUI:C0001175
has_exact_synonym: acquired Immune deficiency
has_related_synonym: acquired immune deficiency syndrome
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: zoonotic infectious disease

acne
type: Class
subclass of: disease
definition: A sebaceous gland disease characterized by areas of blackheads, whiteheads, pimples, greasy skin, and possibly scarring.
has_exact_synonym: Acne varioliformis
id: DOID:6543
has_alternative_id: DOID:9906
database_cross_reference: ICD10CM:L70
database_cross_reference: ICD10CM:L70.2
database_cross_reference: ICD10CM:L70.9
database_cross_reference: ICD9CM:706.0
database_cross_reference: MTH:217
database_cross_reference: NCI:C27195
database_cross_reference: OMIM:604324
database_cross_reference: SNOMEDCT_US_2015_03_01:11381005
database_cross_reference: SNOMEDCT_US_2015_03_01:201210008
database_cross_reference: SNOMEDCT_US_2015_03_01:201211007
database_cross_reference: SNOMEDCT_US_2015_03_01:201212000
database_cross_reference: SNOMEDCT_US_2015_03_01:201229002
database_cross_reference: SNOMEDCT_US_2015_03_01:201408008
database_cross_reference: SNOMEDCT_US_2015_03_01:23894009
database_cross_reference: SNOMEDCT_US_2015_03_01:267815009
database_cross_reference: UMLS_CUI:C0152249
database_cross_reference: UMLS_CUI:C0702166
has_exact_synonym: acne vulgaris
has_obo_namespace: disease_ontology
has_exact_synonym: frontalis acne
imported from: doid.owl

cerebrovascular disease
type: Class
subclass of: disease
definition: An artery disease that is characterized by dysfunction of the blood vessels supplying the brain.
has_exact_synonym: CVA (cerebral vascular accident)
has_exact_synonym: Cerebrovascular accident (disorder)
has_alternative_id: DOID:12214
has_alternative_id: DOID:3455
id: DOID:6713
has_alternative_id: DOID:8231
database_cross_reference: EFO:0000712
database_cross_reference: ICD10CM:I60-I69
database_cross_reference: ICD10CM:I63.9
database_cross_reference: ICD10CM:I67.9
database_cross_reference: ICD9CM:430-438.99
database_cross_reference: ICD9CM:437.9
database_cross_reference: MSH:D002561
database_cross_reference: MSH:D020521
database_cross_reference: NCI:C2938
database_cross_reference: NCI:C3390
comment: OMIM mapping confirmed by DO. [SN].
database_cross_reference: OMIM:601367
database_cross_reference: SNOMEDCT_US_2015_03_01:155388006
database_cross_reference: SNOMEDCT_US_2015_03_01:155405006
database_cross_reference: SNOMEDCT_US_2015_03_01:155412002
database_cross_reference: SNOMEDCT_US_2015_03_01:195208004
database_cross_reference: SNOMEDCT_US_2015_03_01:195249004
database_cross_reference: SNOMEDCT_US_2015_03_01:195595007
database_cross_reference: SNOMEDCT_US_2015_03_01:230690007
database_cross_reference: SNOMEDCT_US_2015_03_01:266312006
database_cross_reference: SNOMEDCT_US_2015_03_01:266315008
database_cross_reference: SNOMEDCT_US_2015_03_01:270883006
database_cross_reference: SNOMEDCT_US_2015_03_01:313267000
database_cross_reference: SNOMEDCT_US_2015_03_01:62914000
database_cross_reference: SNOMEDCT_US_2015_03_01:82797006
database_cross_reference: UMLS_CUI:C0007820
database_cross_reference: UMLS_CUI:C0038454
has_exact_synonym: cerebrovascular accident
has_exact_synonym: cerebrovascular disorder
has_obo_namespace: disease_ontology
has_exact_synonym: stroke
imported from: doid.owl

ankylosing spondylitis
type: Class
subclass of: disease
definition: A bone inflammation disease that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.
has_exact_synonym: Bekhterev syndrome
has_exact_synonym: Bekhterev's disease
id: DOID:7147
database_cross_reference: EFO:0003898
database_cross_reference: ICD10CM:M45
database_cross_reference: ICD9CM:720.0
database_cross_reference: MSH:D013167
has_exact_synonym: Marie-Strumpell disease
database_cross_reference: NCI:C84564
database_cross_reference: ORDO:825
database_cross_reference: SNOMEDCT_US_2015_03_01:156619005
database_cross_reference: SNOMEDCT_US_2015_03_01:9631008
database_cross_reference: UMLS_CUI:C0038013
has_obo_namespace: disease_ontology
imported from: doid.owl

rheumatoid arthritis
type: Class
subclass of: disease
definition: An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.
has_exact_synonym: Arthritis or polyarthritis, rheumatic
id: DOID:7148
database_cross_reference: EFO:0000685
database_cross_reference: ICD10CM:M06.9
database_cross_reference: ICD9CM:714.0
database_cross_reference: KEGG:05323
database_cross_reference: MSH:D001172
database_cross_reference: NCI:C27206
database_cross_reference: NCI:C2884
comment: OMIM mapping confirmed by DO. [SN].
database_cross_reference: OMIM:180300
database_cross_reference: SNOMEDCT_US_2015_03_01:156471009
database_cross_reference: SNOMEDCT_US_2015_03_01:156481008
database_cross_reference: SNOMEDCT_US_2015_03_01:287010008
database_cross_reference: SNOMEDCT_US_2015_03_01:69896004
database_cross_reference: UMLS_CUI:C0003873
has_exact_synonym: atrophic Arthritis
has_obo_namespace: disease_ontology
imported from: doid.owl

lung disease
type: Class
subclass of: disease
definition: A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
has_alternative_id: DOID:11894
has_alternative_id: DOID:11895
has_alternative_id: DOID:29
has_alternative_id: DOID:766
id: DOID:850
database_cross_reference: ICD10CM:J98.4
database_cross_reference: MSH:D008171
database_cross_reference: NCI:C3198
has_exact_synonym: Non-neoplastic pulmonary disorder
database_cross_reference: SNOMEDCT_US_2015_03_01:196164004
database_cross_reference: SNOMEDCT_US_2015_03_01:19829001
database_cross_reference: SNOMEDCT_US_2015_03_01:266374002
database_cross_reference: UMLS_CUI:C0024115
comment: Updating out dated CUI and removing lung abscess as a synonym.
has_obo_namespace: disease_ontology
has_exact_synonym: non-neoplastic lung disorder
imported from: doid.owl

impetigo
type: Class
subclass of: dermatitis
definition: A pyoderma consisting of three forms of skin lesions having either a thick, adherent, recurrent, dirty yellow crust with an erythematous margin (common or superficial impetigo) or lessions which are superficial, thin-walled, and bullous as found in bullous impetigo. The lesions in bullous (staphylococcal) impetigo, which are always caused by S aureus, are superficial, thin-walled, and bullous.
id: DOID:8504
database_cross_reference: ICD10CM:L01
database_cross_reference: ICD10CM:L01.0
database_cross_reference: ICD10CM:L01.00
database_cross_reference: ICD9CM:684
database_cross_reference: MSH:D007169
database_cross_reference: NCI:C99088
database_cross_reference: SNOMEDCT_US_2015_03_01:156319000
database_cross_reference: SNOMEDCT_US_2015_03_01:200710001
database_cross_reference: SNOMEDCT_US_2015_03_01:267836006
database_cross_reference: SNOMEDCT_US_2015_03_01:48277006
database_cross_reference: UMLS_CUI:C0021099
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: gram-positive bacterial infectious disease

herpes zoster
type: Class
subclass of: disease
definition: A viral infectious disease that results_in infection located_in nerve fiber, has_material_basis_in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The virus is transmitted_by direct contact with the rash, which can develop into chickenpox in newly-infected individuals. The infection has_symptom rash which is followed by blisters, has_symptom headache, has_symptom fever, has_symptom malaise, has_symptom itching, has_symptom burning pain, and has_symptom paresthesia.
id: DOID:8536
has_alternative_id: DOID:8554
has_alternative_id: DOID:8555
has_alternative_id: DOID:8772
has_alternative_id: DOID:8801
has_alternative_id: DOID:9085
database_cross_reference: ICD10CM:B02
database_cross_reference: ICD10CM:B02.9
database_cross_reference: ICD9CM:053
database_cross_reference: MSH:D006562
database_cross_reference: NCI:C71079
database_cross_reference: SNOMEDCT_US_2015_03_01:154326002
database_cross_reference: SNOMEDCT_US_2015_03_01:186514003
database_cross_reference: SNOMEDCT_US_2015_03_01:186533008
database_cross_reference: SNOMEDCT_US_2015_03_01:4740000
has_exact_synonym: Shingles
database_cross_reference: UMLS_CUI:C0019360
has_obo_namespace: disease_ontology
has_exact_synonym: herpes zona
imported from: doid.owl

chickenpox
type: Class
subclass of: disease
definition: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human herpesvirus 3, which is transmitted_by direct contact with secretions from the rash, or transmitted_by droplet spread of respiratory secretions. The infection has_symptom anorexia, has_symptom myalgia, has_symptom nausea, has_symptom fever, has_symptom headache, has_symptom sore throat, and has_symptom blisters.
has_alternative_id: DOID:8658
id: DOID:8659
has_alternative_id: DOID:8693
has_alternative_id: DOID:9243
database_cross_reference: ICD10CM:B01
database_cross_reference: ICD10CM:B01.9
database_cross_reference: ICD9CM:052
database_cross_reference: MSH:D002644
database_cross_reference: NCI:C97132
database_cross_reference: SNOMEDCT_US_2015_03_01:154325003
database_cross_reference: SNOMEDCT_US_2015_03_01:186508005
database_cross_reference: SNOMEDCT_US_2015_03_01:38907003
database_cross_reference: UMLS_CUI:C0008049
has_obo_namespace: disease_ontology
has_exact_synonym: varicella
imported from: doid.owl

Crohn's disease
type: Class
subclass of: disease
definition: An intestinal disease that involves inflammation located_in intestine.
has_exact_synonym: Crohn disease
has_exact_synonym: Crohn's disease of colon (disorder)
has_exact_synonym: Crohn's disease of large bowel
id: DOID:8778
has_alternative_id: DOID:8784
has_alternative_id: DOID:8855
has_alternative_id: DOID:8942
database_cross_reference: EFO:0000384
has_exact_synonym: Granulomatous Colitis
database_cross_reference: ICD10CM:K50.0
database_cross_reference: ICD9CM:555.0
comment: MSH:C536215 added from NeuroDevNet [WAK].
database_cross_reference: NCI:C35210
has_exact_synonym: Pediatric Crohn's disease
database_cross_reference: SNOMEDCT_US_2015_03_01:155761004
database_cross_reference: SNOMEDCT_US_2015_03_01:196980005
database_cross_reference: SNOMEDCT_US_2015_03_01:56689002
database_cross_reference: UMLS_CUI:C0156146
has_obo_namespace: disease_ontology
has_exact_synonym: regional Ileitis
has_exact_synonym: regional colitis
has_related_synonym: regional enteritis
has_exact_synonym: regional enteritis of small intestine with large intestine
has_exact_synonym: regional enteritis of the large bowel
has_exact_synonym: regional ileocolitis
imported from: doid.owl

intermediate coronary syndrome
type: Class
subclass of: disease
has_exact_synonym: (Angina: [crescendo] or [unstable] or [at rest]) or (preinfarction syndrome) or (impending infarction)
has_exact_synonym: Angina at rest
has_exact_synonym: Anginal chest pain at rest
id: DOID:8805
database_cross_reference: ICD10CM:I20.0
database_cross_reference: ICD9CM:411.1
has_exact_synonym: Impending infarction (disorder)
database_cross_reference: MSH:D000789
database_cross_reference: NCI:C66911
has_exact_synonym: Preinfarction angina
has_exact_synonym: Preinfarction angina (disorder)
database_cross_reference: SNOMEDCT_US_2015_03_01:155308009
database_cross_reference: SNOMEDCT_US_2015_03_01:155313008
database_cross_reference: SNOMEDCT_US_2015_03_01:155314002
database_cross_reference: SNOMEDCT_US_2015_03_01:194814006
database_cross_reference: SNOMEDCT_US_2015_03_01:194816008
database_cross_reference: SNOMEDCT_US_2015_03_01:194817004
database_cross_reference: SNOMEDCT_US_2015_03_01:194819001
database_cross_reference: SNOMEDCT_US_2015_03_01:233818002
database_cross_reference: SNOMEDCT_US_2015_03_01:233820004
database_cross_reference: SNOMEDCT_US_2015_03_01:25106000
database_cross_reference: SNOMEDCT_US_2015_03_01:4557003
database_cross_reference: SNOMEDCT_US_2015_03_01:59021001
database_cross_reference: SNOMEDCT_US_2015_03_01:64333001
database_cross_reference: UMLS_CUI:C0002965
has_exact_synonym: Unstable angina
has_exact_synonym: Worsening angina
has_obo_namespace: disease_ontology
imported from: doid.owl

psoriasis
type: Class
subclass of: disease
id: DOID:8893
database_cross_reference: EFO:0000676
database_cross_reference: ICD10CM:L40
database_cross_reference: ICD10CM:L40.9
database_cross_reference: MSH:D011565
database_cross_reference: NCI:C3346
database_cross_reference: OMIM:177900
database_cross_reference: OMIM:601454
database_cross_reference: OMIM:602723
database_cross_reference: OMIM:603935
database_cross_reference: OMIM:604316
database_cross_reference: OMIM:605364
database_cross_reference: OMIM:605606
database_cross_reference: OMIM:607857
database_cross_reference: OMIM:610707
database_cross_reference: OMIM:612410
database_cross_reference: OMIM:612599
database_cross_reference: OMIM:612950
database_cross_reference: OMIM:614070
database_cross_reference: SNOMEDCT_US_2015_03_01:156369008
database_cross_reference: SNOMEDCT_US_2015_03_01:156371008
database_cross_reference: SNOMEDCT_US_2015_03_01:200961000
database_cross_reference: SNOMEDCT_US_2015_03_01:200978009
database_cross_reference: SNOMEDCT_US_2015_03_01:267851002
database_cross_reference: SNOMEDCT_US_2015_03_01:9014002
database_cross_reference: UMLS_CUI:C0033860
has_obo_namespace: disease_ontology
imported from: doid.owl
in_subset: DO MGI slim

systemic lupus erythematosus
type: Class
subclass of: disease
subclass of: hypersensitivity reaction type II disease
definition: A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
id: DOID:9074
database_cross_reference: EFO:0002690
database_cross_reference: ICD10CM:M32
database_cross_reference: ICD10CM:M32.9
database_cross_reference: ICD9CM:710.0
database_cross_reference: KEGG:05322
has_exact_synonym: Lupus Erythematosus, systemic
database_cross_reference: MSH:D008180
database_cross_reference: NCI:C3201
database_cross_reference: OMIM:152700
database_cross_reference: OMIM:300809
database_cross_reference: OMIM:601744
database_cross_reference: OMIM:605218
database_cross_reference: OMIM:605480
database_cross_reference: OMIM:608437
database_cross_reference: OMIM:609903
database_cross_reference: OMIM:609939
database_cross_reference: OMIM:610065
database_cross_reference: OMIM:610066
database_cross_reference: OMIM:610927
database_cross_reference: OMIM:612251
database_cross_reference: OMIM:612253
database_cross_reference: OMIM:612254
database_cross_reference: OMIM:612378
database_cross_reference: OMIM:613145
database_cross_reference: OMIM:614420
database_cross_reference: ORDO:536
has_exact_synonym: SLE - Lupus Erythematosus, systemic
database_cross_reference: SNOMEDCT_US_2015_03_01:156450004
database_cross_reference: SNOMEDCT_US_2015_03_01:201435004
database_cross_reference: SNOMEDCT_US_2015_03_01:201439005
database_cross_reference: SNOMEDCT_US_2015_03_01:55464009
database_cross_reference: UMLS_CUI:C0024141
comment: Xref MGI.
has_obo_namespace: disease_ontology
has_exact_synonym: disseminated lupus erythematosus
imported from: doid.owl
in_subset: DO MGI slim

diabetes mellitus
type: Class
subclass of: disease
definition: A glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
id: DOID:9351
database_cross_reference: ICD10CM:E08-E13
database_cross_reference: ICD10CM:E11
database_cross_reference: ICD9CM:250
database_cross_reference: MSH:D003920
database_cross_reference: NCI:C2985
database_cross_reference: SNOMEDCT_US_2015_03_01:154671004
database_cross_reference: SNOMEDCT_US_2015_03_01:191044006
database_cross_reference: SNOMEDCT_US_2015_03_01:267467004
database_cross_reference: SNOMEDCT_US_2015_03_01:73211009
database_cross_reference: UMLS_CUI:C0011849
has_obo_namespace: disease_ontology
imported from: doid.owl

geographic location
type: Class
subclass of: site
definition: A reference to a place on the Earth, by its name or by its geographical location.
has_obo_namespace: GAZ
id: GAZ:00000448
has_alternative_id: GAZ:00000467
has_exact_synonym: geographic region {alternative name}
imported from: gaz.owl
type: NamedIndividual

United States of America
type: Class
subclass of: geographic location
definition: A federal constitutional republic comprising fifty states and a federal district. The country is situated mostly in central North America, where its forty-eight contiguous states and Washington, DC, the capital district, lie between the Pacific and Atlantic Oceans, bordered by Canada to the north and Mexico to the south. The State of Alaska is in the northwest of the continent, with Canada to its east and Russia to the west across the Bering Strait, and the State of Hawaii is in the mid-Pacific. The United States also possesses several territories, or insular areas, that are scattered around the Caribbean and Pacific. The states are divided into smaller administrative regions, called counties in most states, exceptions being Alaska (parts of the state are organized into subdivisions called boroughs; the rest of the state's territory that is not included in any borough is divided into "census areas"), and Louisiana (which is divided into county-equivalents that are called parishes). There are also independent cities which are within particular states but not part of any particular county or consolidated city-counties. Another type of organization is where the city and county are unified and function as an independent city. There are thirty-nine independent cities in Virginia and other independent cities or city-counties are San Francisco, California, Baltimore, Maryland, St. Louis, Missouri, Denver, Colorado and Carson City, Nevada. Counties can include a number of cities, towns, villages, or hamlets, or sometimes just a part of a city. Counties have varying degrees of political and legal significance, but they are always administrative divisions of the state. Counties in many states are further subdivided into townships, which, by definition, are administrative divisions of a county. In some states, such as Michigan, a township can file a charter with the state government, making itself into a "charter township", which is a type of mixed municipal and township statu…
has_obo_namespace: GAZ
id: GAZ:00002459
database_cross_reference: ISO3166-1:840
database_cross_reference: ISO3166-1:US
database_cross_reference: ISO3166-1:USA
database_cross_reference: ISO3166-2:US
has_exact_synonym: U.S.A
has_exact_synonym: USA
imported from: gaz.owl
type: NamedIndividual

Territory of Guam
type: Class
subclass of: Unincorporated Territory (USA)
definition: An unincorporated territory of the United States.
has_obo_namespace: GAZ
id: GAZ:00003706
database_cross_reference: GNISID:01802705
has_exact_synonym: GU
database_cross_reference: INCITS38:66
database_cross_reference: ISO3166-1:316
database_cross_reference: ISO3166-1:GU
database_cross_reference: ISO3166-1:GUM
database_cross_reference: ISO3166-2:US-GU
comment: lat_lon: 13deg27minN, 144deg47minE.
imported from: gaz.owl
type: NamedIndividual
located_in: Micronesia
located_in: Southern Marianas Islands

Unincorporated Territory (USA)
type: Class
subclass of: geographic location
definition: An area of the United States of America under United States jurisdiction, to which Congress has determined that only select parts of the United States of America Constitution apply.
has_obo_namespace: GAZ
id: GAZ:00003956
imported from: gaz.owl
type: NamedIndividual
located_in: United States of America

American Samoa
type: Class
subclass of: Unincorporated Territory (USA)
has_exact_synonym: AS
definition: An unincorporated territory of the United States located in the South Pacific Ocean, southeast of the sovereign State of Samoa. The main (largest and most populous) island is Tutuila, with the Manu'a Islands, Rose Atoll, and Swains Island also included in the territory.
has_obo_namespace: GAZ
id: GAZ:00003957
database_cross_reference: GNISID:01802701
database_cross_reference: INCITS38:60
database_cross_reference: ISO3166-1:016
database_cross_reference: ISO3166-1:AS
database_cross_reference: ISO3166-1:ASM
database_cross_reference: ISO3166-2:AS
database_cross_reference: ISO3166-2:US-AS
imported from: gaz.owl
type: NamedIndividual
type: Unincorporated Territory (USA)
located_in: Samoan Archipelago

United States Virgin Islands
type: Class
subclass of: Unincorporated Territory (USA)
definition: A group of islands in the Caribbean that are an insular area of the United States. The islands are geographically part of the Virgin Islands archipelago and are located in the Leeward Islands of the Lesser Antilles. The US Virgin Islands are an organized, unincorporated United States territory. The US Virgin Islands are administratively divided into two districts and subdivided into 20 sub-districts.
has_obo_namespace: GAZ
id: GAZ:00003959
database_cross_reference: GNISID:01802710
database_cross_reference: INCITS38:78
database_cross_reference: ISO3166-1:850
database_cross_reference: ISO3166-1:VI
database_cross_reference: ISO3166-1:VIR
database_cross_reference: ISO3166-2:US-VI
has_exact_synonym: US Virgin Islands
has_exact_synonym: VI
imported from: gaz.owl
type: NamedIndividual
located_in: Virgin Islands Archipelago

Republic of the Marshall Islands
type: Class
subclass of: Unincorporated Territory (USA)
definition: A Micronesian island nation in the western Pacific Ocean, located north of Nauru and Kiribati, east of the Federated States of Micronesia and south of the United States territory of Wake Island, to which it lays claim.
has_obo_namespace: GAZ
id: GAZ:00006470
database_cross_reference: ISO3166-1:584
database_cross_reference: ISO3166-1:MH
database_cross_reference: ISO3166-1:MHL
database_cross_reference: ISO3166-2:MH
imported from: gaz.owl
type: NamedIndividual
located_in: Marshall Islands

Commonwealth of Puerto Rico
type: Class
subclass of: Unincorporated Territory (USA)
definition: A semi-autonomous territory composed of an archipelago in the northeastern Caribbean, east of the Dominican Republic and west of the Virgin Islands, approximately 2,000 km off the coast of Florida (the nearest of the mainland United States).
has_exact_synonym: Estado Libre Asociado de Puerto Rico
has_obo_namespace: GAZ
id: GAZ:00006935
database_cross_reference: GNISID:01779808
database_cross_reference: INCITS38:72
database_cross_reference: ISO3166-1:630
database_cross_reference: ISO3166-1:PR
database_cross_reference: ISO3166-1:PRI
database_cross_reference: ISO3166-2:US-PR
imported from: gaz.owl
type: NamedIndividual
type: Unincorporated Territory (USA)
located_in: Greater Antilles

Northern Marianas
type: Class
subclass of: Unincorporated Territory (USA)
definition: A commonwealth in political union with the United States.
has_exact_synonym: Commonwealth of the Northern Mariana Islands
has_obo_namespace: GAZ
id: GAZ:00007109
database_cross_reference: GNISID:01779809
database_cross_reference: INCITS38:69
database_cross_reference: ISO3166-1:580
database_cross_reference: ISO3166-1:MNP
database_cross_reference: ISO3166-1:MP
database_cross_reference: ISO3166-2:US-MP
has_exact_synonym: MP
has_exact_synonym: Sankattan Siha Na Islas Marianas
imported from: gaz.owl
type: NamedIndividual
located_in: Northern Mariana Islands
located_in: Micronesia

Territory of Wake Island
type: Class
subclass of: Unincorporated Territory (USA)
definition: An unorganized, unincorporated territory of the United States, administered by the Office of Insular Affairs, US Department of the Interior.
has_obo_namespace: GAZ
id: GAZ:00007110
database_cross_reference: ISO3166-2:UM-79
imported from: gaz.owl
type: NamedIndividual
located_in: Micronesia
located_in: Wake Island

United States Minor Outlying Islands
type: Class
subclass of: Unincorporated Territory (USA)
definition: A statistical designation defined by ISO3166-1, consists of nine insular United States possessions. Palmyra Atoll is the only incorporated territory of the United States. Currently, none of the islands have any permanent residents.
has_obo_namespace: GAZ
id: GAZ:00007113
database_cross_reference: GNISID:01878752
database_cross_reference: INCITS38:74
database_cross_reference: ISO3166-1:581
database_cross_reference: ISO3166-1:UM
database_cross_reference: ISO3166-1:UMI
database_cross_reference: ISO3166-2:US-UM
imported from: gaz.owl
type: NamedIndividual

objective specification
type: Class
subclass of: generically dependent continuant
subclass of: directive information entity
editor note: 2009-03-16: original definition when imported from OBI read: "objective is an non realizable information entity which can serve as that proper part of a plan towards which the realization of the plan is directed."
editor note: 2014-03-31: In the example of usage ("In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that.
editor note: Answers the question, why did you do this experiment?
example of usage: In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction.
definition source: OBI Plan and Planned Process/Roles Branch
definition source: OBI_0000217
term editor: PERSON: Alan Ruttenberg
term editor: PERSON: Barry Smith
term editor: PERSON: Bjoern Peters
term editor: PERSON: Jennifer Fostel
definition: a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.
alternative term: goal specification
editor preferred term: objective specification
example of usage: purpose of a study; support of hypothesis, discovery of new information
has curation status: ready for release
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl

action specification
type: Class
subclass of: directive information entity
term editor: Alan Ruttenberg
definition source: OBI Plan and Planned Process branch
example of usage: Pour the contents of flask 1 into flask 2
definition: a directive information entity that describes an action the bearer will take
editor preferred term: action specification
has curation status: ready for release
has curation status: metadata incomplete
imported from: ico.owl
imported from: obi.owl

data item
type: Class
subclass of: information content entity
editor note: 2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum.
editor note: 2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym.
editor note: 2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/
editor note: 2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers.
example of usage: Data items include counts of things, analyte concentrations, and statistical summaries.
term editor: PERSON: Alan Ruttenberg
term editor: PERSON: Chris Stoeckert
term editor: PERSON: Jonathan Rees
definition: a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.
alternative term: data
editor preferred term: data item
has curation status: ready for release
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl

symbol
type: Class
subclass of: information content entity
editor note: 20091104, MC: this needs work and will most probably change
editor note: 2014-03-31: We would like to have a deeper analysis of 'mark' and 'sign' in the future (see https://code.google.com/p/information-artifact-ontology/issues/detail?id=154).
definition: An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.
term editor: PERSON: James A. Overton
term editor: PERSON: Jonathan Rees
example of usage: a serial number such as "12324X"
example of usage: a stop sign
example of usage: a written proper name such as "OBI"
definition source: based on Oxford English Dictionary
editor preferred term: symbol
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl

information content entity
type: Class
subclass of: generically dependent continuant
subclass of: Restriction
  on property: is about
  some values from: entity
editor note: 2014-03-10: The use of "thing" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ).
definition: A generically dependent continuant that is about some thing.
example of usage: Examples of information content entites include journal articles, data, graphical layouts, and graphs.
definition source: OBI_0000142
term editor: PERSON: Chris Stoeckert
editor preferred term: information content entity
has curation status: ready for release
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl

directive information entity
type: Class
subclass of: information content entity
subclass of: Restriction
  on property: is about
  some values from: realizable entity
editor note: 2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was "is the specification of a process that can be concretized and realized by an actor" with alternative term "instruction".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term.
editor note: 2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it.
editor note: 8/6/2009 Alan Ruttenberg: Changed label from "information entity about a realizable" after discussions at ICBO
definition: An information content entity whose concretizations indicate to their bearer how to realize them in a process.
term editor: PERSON: Alan Ruttenberg
term editor: PERSON: Bjoern Peters
editor note: Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan
editor preferred term: directive information entity
has curation status: ready for release
has curation status: metadata incomplete
imported from: ico.owl
imported from: obi.owl

curation status specification
type: Class
equivalent class: Class
  one of: ready for release
  one of: metadata incomplete
  one of: example to be eventually removed
  one of: uncurated
  one of: pending final vetting
  one of: metadata complete
  one of: organizational term
  one of: requires discussion
  one of: to be replaced with external ontology term
subclass of: data about an ontology part
editor note: Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
definition source: OBI_0000266
term editor: PERSON:Bill Bug
definition: The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
editor preferred term: curation status specification
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl

data about an ontology part
type: Class
subclass of: data item
term editor: Person:Alan Ruttenberg
editor preferred term: data about an ontology part
definition: data about an ontology part is a data item about a part of an ontology, for example a term
imported from: ico.owl
imported from: obi.owl

plan specification
type: Class
subclass of: directive information entity
subclass of: Restriction
  on property: has part
  some values from: action specification
subclass of: Restriction
  on property: has part
  some values from: objective specification
editor note: 2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was " a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term.
editor note: 2014-03-31: A plan specification can have other parts, such as conditional specifications.
definition: A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.
term editor: Alan Ruttenberg
editor note: Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved
definition source: OBI Plan and Planned Process branch
definition source: OBI_0000344
example of usage: PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice.
editor preferred term: plan specification
has curation status: metadata complete
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

textual entity
type: Class
subclass of: information content entity
definition: A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc.
editor note: AR, (IAO call 2009-09-01): a document as a whole is not typically a textual entity, because it has pictures in it - rather there are parts of it that are textual entities. Examples: The title, paragraph 2 sentence 7, etc.
editor note: MC, 2009-09-14 (following IAO call 2009-09-01): textual entities live at the FRBR (http://en.wikipedia.org/wiki/Functional_Requirements_for_Bibliographic_Records) manifestation level. Everything is significant: line break, pdf and html versions of same document are different textual entities.
term editor: PERSON: Lawrence Hunter
example of usage: Words, sentences, paragraphs, and the written (non-figure) parts of publications are all textual entities
alternative term: text
editor preferred term: textual entity
has curation status: metadata incomplete
imported from: ico.owl
imported from: obi.owl

document
type: Class
subclass of: information content entity
definition: A collection of information content entities intended to be understood together as a whole
example of usage: A journal article, patent application, laboratory notebook, or a book
term editor: PERSON: Lawrence Hunter
editor preferred term: document
has curation status: metadata complete
imported from: ico.owl
imported from: obi.owl

documenting
type: Class
subclass of: planned process
subclass of: Restriction
  on property: has_specified_output
  some values from: document
subclass of: Restriction
  on property: has_specified_input
  some values from: information content entity
term_mapping_to_HL7v3: 11609
editor note: 6/11/9: Edited at OBI workshop. We need to be able identify a child form of information artifact which corresponds to something enduring (not brain like). This used to be restricted to physical document or digital entity as the output, but that excludes e.g. an audio cassette tape
term editor: Bjoern Peters
term_mapping_to_UMLS: C1548385
example of usage: Recording the current temperature in a laboratory notebook. Writing a journal article. Updating a patient record in a database.
definition: a planned process in which a document is created or added to by including the specified input in it.
editor preferred term: documenting
definition source: wikipedia http://en.wikipedia.org/wiki/Documenting
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl

informed consent form
type: Class
subclass of: document
subclass of: Restriction
  on property: is associated with review board approval number
  some values from: review board approval number
definition source: NCIt C16468
term editor: AK, FM, YH, YL, MH, EE
editor note: The term definition is adapted from NCIt definition of 'consent form' (C16468) with modification. Compared to the NCIt definition, the ICO definition does not restrict the form to a clinical trial.
definition: A document that explains all relevant study information to assist a human subject in understanding the expectations and requirements of participation in a research study. This form document is presented to and signed by the study subject.
term_mapping_to_UMLS: C0009797
term_mapping_to_NCIT: C16468
imported from: ico.owl

informed consent form design
type: Class
subclass of: planned process
subclass of: Restriction
  on property: has_specified_output
  some values from: informed consent form
term editor: AK, FM, YH
definition: a planned process that involves the design of an informed consent form.
imported from: ico.owl

informed consent regulatory body
type: Class
subclass of: organization
term editor: AK, FM, YH
definition: an organization that approves the clinical study protocol, and ensures the applicable governing rules and laws are upheld.
imported from: ico.owl

study requiring informed consent
type: Class
subclass of: investigation
term editor: YH
definition: a planned process that is a study requiring an official informed consent process.
imported from: ico.owl

consenter role
type: Class
subclass of: role
creator: YL
definition: a role that inheres in a patient or the legal guadian when he/she participates the consenting process.
imported from: ico.owl

review board approval number
type: Class
subclass of: symbol
subclass of: Restriction
  on property: is assigned by organization
  some values from: informed consent regulatory body
term_mapping_to_UMLS: C2985863
editor note: For the review board approval, different countries or continents may have different responsible entities for approving the study. For example, in USA, the board is called "Institutional Review Board" (IRB). In many countries in Europe, it is called Ethics committee.
editor note: This term definition is adapted from the definition of the NCIt term 'Review Board Approval Number Text'.
definition: A character string that is assigned by the review board upon approval of the study.
term_mapping_to_NCIT: C93662
term editor: YL, EE, YH, AK, MH
imported from: ico.owl

vaccination informed consent form
type: Class
subclass of: informed consent form
alternative term: immunization consent form
definition: an informed consent form that is used for vaccination
term editor: YH, YL
imported from: ico.owl

question textual entity
type: Class
subclass of: textual entity
subclass of: Restriction
  on property: is about
  some values from: study requiring informed consent
definition: a textual entity that provides a question in text.
term editor: YL, YH
imported from: ico.owl

filled questionnaire
type: Class
equivalent class: Class
  intersection of: questionnaire
  intersection of: Restriction
    on property: is_specified_output_of
    some values from: filling questionnaire
subclass of: questionnaire
definition: A questionaire that is filled up with answers.
term editor: YH, YL
imported from: ico.owl

answer option text entity
type: Class
subclass of: textual entity
subclass of: Restriction
  on property: is about
  some values from: study requiring informed consent
term editor: YL, YH, JZ
definition: a textual entity that answers a question with an option.
imported from: ico.owl

yes answer text entity
type: Class
subclass of: answer option text entity
subclass of: Restriction
  on property: is about
  some values from: study requiring informed consent
definition: an answer option textual entity that answers a question with a yes.
term editor: YL, YH, JZ
imported from: ico.owl

no answer text entity
type: Class
subclass of: answer option text entity
subclass of: Restriction
  on property: is about
  some values from: study requiring informed consent
term editor: YL, YH, JZ
definition: an answer option textual entity that answers a question with a no.
imported from: ico.owl

filling informed consent form
type: Class
subclass of: planned process
term editor: YH, YL
definition: a planned process that involves the filling of an informed consent form.
imported from: ico.owl

filling questionnaire
type: Class
subclass of: planned process
definition: a planned process that involves the filling of a questionnaire form that includes a list of questions.
term editor: YH, YL
imported from: ico.owl

Viruses
type: Class
subclass of: organism
database_cross_reference: GC_ID:1
has_related_synonym: Vira
has_related_synonym: Viridae
editor preferred term: Viruses
has_obo_namespace: ncbi_taxonomy
has_related_synonym: viruses
has_rank: NCBITaxon superkingdom
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl
imported from: vo.owl

Variola virus
type: Class
subclass of: dsDNA viruses, no RNA stage
database_cross_reference: GC_ID:1
has_alternative_id: NCBITaxon:12871
has_obo_namespace: ncbi_taxonomy
has_exact_synonym: small pox virus
has_exact_synonym: smallpox
has_exact_synonym: smallpox virus
has_related_synonym: variola virus VAR
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

H5N1 subtype
type: Class
subclass of: Influenza A virus
database_cross_reference: GC_ID:1
has_related_synonym: H5N1
has_obo_namespace: ncbi_taxonomy
imported from: ncbitaxon.owl
imported from: vo.owl

Human herpesvirus 3
type: Class
subclass of: dsDNA viruses, no RNA stage
database_cross_reference: GC_ID:1
has_broad_synonym: HHV-3
has_related_synonym: Human alphaherpesvirus 3
has_broad_synonym: VZV
has_related_synonym: Varicella Zoster Virus
has_exact_synonym: Varicella-zoster virus
has_obo_namespace: ncbi_taxonomy
has_related_synonym: varicella zoster virus VZV
has_related_synonym: varicella-zoster virus VZV
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Hepatitis B virus
type: Class
subclass of: Viruses
database_cross_reference: GC_ID:1
has_broad_synonym: HBV
has_related_synonym: Human hepatitis B virus
has_related_synonym: hepatitis B virus (HBV)
has_related_synonym: hepatitis B virus HBV
has_related_synonym: hepatitis B virus, HBV
has_related_synonym: human hepatitis B virus HBV
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Human papillomavirus
type: Class
subclass of: dsDNA viruses, no RNA stage
database_cross_reference: GC_ID:1
has_related_synonym: Human Papilloma Virus
has_related_synonym: human papillomavirus HPV
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Rotavirus
type: Class
subclass of: Viruses
database_cross_reference: GC_ID:1
has_related_synonym: Rotaviruses
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon genus
imported from: ncbitaxon.owl
imported from: vo.owl

Rubella virus
type: Class
subclass of: ssRNA positive-strand viruses, no DNA stage
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Flavivirus
type: Class
subclass of: ssRNA positive-strand viruses, no DNA stage
database_cross_reference: GC_ID:1
has_exact_synonym: arboviruses group B
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon genus
imported from: ncbitaxon.owl
imported from: vo.owl

Japanese encephalitis virus
type: Class
subclass of: Flavivirus
database_cross_reference: GC_ID:1
has_related_synonym: Japanese encephalitis
has_related_synonym: Japanese encephalitis (JE) virus
has_related_synonym: Japanese encephalitis virus JE
has_related_synonym: Japanese encephalitis virus JEV
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Tick-borne encephalitis virus
type: Class
subclass of: Flavivirus
has_related_synonym: FSME virus
database_cross_reference: GC_ID:1
has_broad_synonym: TBEV
has_obo_namespace: ncbi_taxonomy
has_related_synonym: tick-borne encephalitis virus TBE virus
has_related_synonym: tick-borne encephalitis virus TBEV
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Yellow fever virus
type: Class
subclass of: Flavivirus
has_related_synonym: Flavivirus febricis
database_cross_reference: GC_ID:1
has_broad_synonym: YFV
has_obo_namespace: ncbi_taxonomy
has_related_synonym: yellow fever virus YFV
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Mononegavirales
type: Class
subclass of: ssRNA negative-strand viruses
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_exact_synonym: negative-sense genome single-stranded RNA viruses
has_rank: NCBITaxon order
imported from: ncbitaxon.owl
imported from: vo.owl

Paramyxovirinae
type: Class
subclass of: Mononegavirales
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon subfamily
imported from: ncbitaxon.owl
imported from: vo.owl

Mumps virus
type: Class
subclass of: Paramyxovirinae
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Measles virus
type: Class
subclass of: Paramyxovirinae
has_related_synonym: Cell-associated subacute sclerosing panencephalitis
database_cross_reference: GC_ID:1
has_alternative_id: NCBITaxon:11230
has_related_synonym: Subacute sclerosing panencephalitis virus
has_related_synonym: measles virus MV
has_obo_namespace: ncbi_taxonomy
has_related_synonym: rougeole virus
has_related_synonym: rubeola virus
has_related_synonym: subacute sclerose panencephalitis virus
has_related_synonym: subacute sclerosing panencephalitis virus, SSPEV
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Rabies virus
type: Class
subclass of: Mononegavirales
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Orthomyxoviridae
type: Class
subclass of: ssRNA negative-strand viruses
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon family
imported from: ncbitaxon.owl
imported from: vo.owl

Influenza A virus
type: Class
subclass of: Orthomyxoviridae
has_broad_synonym: FLUAV
database_cross_reference: GC_ID:1
has_related_synonym: Influenza virus type A
has_related_synonym: influenza A virus INF A
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

H1N1 subtype
type: Class
subclass of: Influenza A virus
database_cross_reference: GC_ID:1
has_related_synonym: H1N1
has_obo_namespace: ncbi_taxonomy
imported from: ncbitaxon.owl
imported from: vo.owl

Euteleostomi
type: Class
subclass of: Vertebrata <Metazoa>
editor preferred term: Euteleostomi
alternative term: bony vertebrates
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Hepatitis A virus
type: Class
subclass of: ssRNA positive-strand viruses, no DNA stage
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Proteobacteria
type: Class
subclass of: Bacteria
subclass of: Restriction
  on property: has part
  some values from: genome of Proteobacteria
database_cross_reference: GC_ID:11
database_cross_reference: PMID:11321122
database_cross_reference: PMID:11542017
database_cross_reference: PMID:11837318
database_cross_reference: PMID:16280474
has_obo_namespace: ncbi_taxonomy
has_related_synonym: proteobacteria
has_exact_synonym: purple bacteria
has_exact_synonym: purple bacteria and relatives
has_exact_synonym: purple non-sulfur bacteria
has_exact_synonym: purple photosynthetic bacteria
has_exact_synonym: purple photosynthetic bacteria and relatives
has_rank: NCBITaxon phylum
imported from: ncbitaxon.owl
imported from: ogg.owl
imported from: vo.owl

Gammaproteobacteria
type: Class
subclass of: Proteobacteria
database_cross_reference: GC_ID:11
has_related_synonym: Gammaproteobacteria Garrity et al. 2005
database_cross_reference: PMID:16280474
has_related_synonym: Proteobacteria gamma subdivision
has_related_synonym: Purple bacteria, gamma subdivision
has_related_synonym: g-proteobacteria
has_related_synonym: gamma proteobacteria
has_related_synonym: gamma subdivision
has_related_synonym: gamma subgroup
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon class
imported from: ncbitaxon.owl
imported from: vo.owl

Firmicutes
type: Class
subclass of: Bacteria
has_related_synonym: Bacillus/Clostridium group
has_related_synonym: Clostridium group firmicutes
has_related_synonym: Firmacutes
database_cross_reference: GC_ID:11
has_related_synonym: Gram positive bacteria
has_exact_synonym: Gram-positive bacteria
has_related_synonym: Low G+C firmicutes
has_alternative_id: NCBITaxon:31968
database_cross_reference: PMID:10555317
database_cross_reference: PMID:11034484
database_cross_reference: PMID:11542017
database_cross_reference: PMID:15143038
has_related_synonym: clostridial firmicutes
has_related_synonym: firmicutes
has_exact_synonym: low G+C Gram-positive bacteria
has_exact_synonym: low GC Gram+
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon phylum
imported from: ncbitaxon.owl
imported from: vo.owl

Streptococcus pneumoniae
type: Class
subclass of: Bacilli
has_related_synonym: Diplococcus pneumoniae
database_cross_reference: GC_ID:11
has_related_synonym: Micrococcus pneumoniae
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Bacillus anthracis
type: Class
subclass of: Bacilli
has_related_synonym: Bacillus cereus var. anthracis
has_related_synonym: Bacteridium anthracis
database_cross_reference: GC_ID:11
database_cross_reference: PMID:8123566
has_exact_synonym: anthrax
has_exact_synonym: anthrax bacterium
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Clostridium tetani
type: Class
subclass of: Firmicutes
has_related_synonym: Bacillus tetani
database_cross_reference: GC_ID:11
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Corynebacterium diphtheriae
type: Class
subclass of: Corynebacterineae
has_related_synonym: Bacillus diphtheriae
has_related_synonym: Bacterium diphtheriae
database_cross_reference: GC_ID:11
has_related_synonym: Microsporon diphthericum
has_related_synonym: Microsporon diphtheriticum
has_related_synonym: Mycobacterium diphtheriae
database_cross_reference: PMID:7729671
has_related_synonym: Pacinia loeffleri
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Mycobacterium tuberculosis
type: Class
subclass of: Corynebacterineae
has_related_synonym: Bacillus tuberculosis
has_related_synonym: Bacterium tuberculosis
database_cross_reference: GC_ID:11
has_related_synonym: Mycobacterium tuberculosis typus humanus
has_related_synonym: Mycobacterium tuberculosis var. hominis
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Influenzavirus B
type: Class
subclass of: Orthomyxoviridae
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon genus
imported from: ncbitaxon.owl
imported from: vo.owl

Bacteria
type: Class
subclass of: organism
subclass of: Restriction
  on property: has part
  some values from: genome of Bacteria
editor preferred term: Bacteria
database_cross_reference: GC_ID:11
has_related_synonym: Monera
database_cross_reference: PMID:10425795
database_cross_reference: PMID:10425796
database_cross_reference: PMID:10425797
database_cross_reference: PMID:10490293
database_cross_reference: PMID:10843050
database_cross_reference: PMID:10939651
database_cross_reference: PMID:10939673
database_cross_reference: PMID:10939677
database_cross_reference: PMID:11211268
database_cross_reference: PMID:11321083
database_cross_reference: PMID:11321113
database_cross_reference: PMID:11411719
database_cross_reference: PMID:11540071
database_cross_reference: PMID:11542017
database_cross_reference: PMID:11542087
database_cross_reference: PMID:11760965
database_cross_reference: PMID:12054223
database_cross_reference: PMID:2112744
database_cross_reference: PMID:270744
database_cross_reference: PMID:8123559
database_cross_reference: PMID:8590690
database_cross_reference: PMID:9103655
database_cross_reference: PMID:9336922
has_related_synonym: Procaryotae
has_related_synonym: Prokaryota
has_related_synonym: Prokaryotae
has_related_synonym: bacteria
alternative term: eubacteria
has_exact_synonym: eubacteria
has_obo_namespace: ncbi_taxonomy
has_related_synonym: not Bacteria Haeckel 1894
has_related_synonym: prokaryote
has_related_synonym: prokaryotes
has_rank: NCBITaxon superkingdom
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

Archaea
type: Class
subclass of: organism
editor preferred term: Archaea
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Eukaryota
type: Class
subclass of: organism
editor preferred term: Eukaryota
alternative term: eucaryotes
alternative term: eukaryotes
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Betaproteobacteria
type: Class
subclass of: Proteobacteria
has_related_synonym: 'Betaproteobacteria'
database_cross_reference: GC_ID:11
has_related_synonym: Proteobacteria beta subdivision
has_related_synonym: Purple bacteria, beta subdivision
has_related_synonym: b-proteobacteria
has_related_synonym: beta proteobacteria
has_related_synonym: beta subdivision
has_related_synonym: beta subgroup
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon class
imported from: ncbitaxon.owl
imported from: vo.owl

Euarchontoglires
type: Class
subclass of: Mammalia
editor preferred term: Euarchontoglires
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Tetrapoda
type: Class
subclass of: Euteleostomi
editor preferred term: Tetrapoda
alternative term: tetrapods
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Amniota
type: Class
subclass of: Tetrapoda
editor preferred term: Amniota
alternative term: amniotes
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Opisthokonta
type: Class
subclass of: Eukaryota
editor preferred term: Opisthokonta
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Bilateria
type: Class
subclass of: Opisthokonta
subclass of: organism
editor preferred term: Bilateria
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl
imported from: vo.owl

dsDNA viruses, no RNA stage
type: Class
subclass of: Viruses
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
imported from: ncbitaxon.owl
imported from: vo.owl

ssRNA positive-strand viruses, no DNA stage
type: Class
subclass of: ssRNA viruses
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
imported from: ncbitaxon.owl
imported from: vo.owl

ssRNA negative-strand viruses
type: Class
subclass of: ssRNA viruses
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
imported from: ncbitaxon.owl
imported from: vo.owl

Mammalia
type: Class
subclass of: Amniota
editor preferred term: Mammalia
alternative term: mammals
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

ssRNA viruses
type: Class
subclass of: Viruses
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
imported from: ncbitaxon.owl
imported from: vo.owl

Neisseria meningitidis
type: Class
subclass of: Betaproteobacteria
has_related_synonym: Diplokokkus intracellularis meningitidis
database_cross_reference: GC_ID:11
has_related_synonym: Micrococcus intracellularis
has_related_synonym: Micrococcus meningitidis
has_related_synonym: Micrococcus meningitidis cerebrospinalis
has_related_synonym: Neisseria meningitidis.
has_related_synonym: Neisseria weichselbaumii
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Bordetella pertussis
type: Class
subclass of: Betaproteobacteria
has_related_synonym: Bacterium tussis-convulsivae
database_cross_reference: GC_ID:11
has_related_synonym: Haemophilus pertussis
has_related_synonym: Hemophilus pertussis
has_related_synonym: Microbe de la coqueluche
database_cross_reference: PMID:8240949
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Enterobacteriaceae
type: Class
subclass of: Gammaproteobacteria
has_related_synonym: Enterobacteraceae
has_related_synonym: Enterobacteraceae (ex Lapage 1979) Lapage 1982, fam. nov., nom. rev.
has_related_synonym: Enterobacteriaceae (ex Rahn 1937) Ewing et al. 1980, fam. nov., nom. rev.
has_related_synonym: Enterobacteriaceae Rahn 1937
database_cross_reference: GC_ID:11
database_cross_reference: PMID:10555323
database_cross_reference: PMID:10555334
database_cross_reference: PMID:16166704
has_related_synonym: gamma-3 proteobacteria
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon family
imported from: ncbitaxon.owl
imported from: vo.owl

Dintheria
type: Class
subclass of: Bilateria
database_cross_reference: GC_ID:1
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon genus
imported from: ncbitaxon.owl
imported from: vo.owl

Escherichia coli
type: Class
subclass of: Enterobacteriaceae
has_related_synonym: Bacillus coli
has_related_synonym: Bacterium coli
has_related_synonym: Bacterium coli commune
has_related_synonym: Enterococcus coli
has_related_synonym: Escherchia coli
has_related_synonym: Eschericia coli
database_cross_reference: GC_ID:11
has_alternative_id: NCBITaxon:662101
has_alternative_id: NCBITaxon:662104
database_cross_reference: PMID:10319482
has_related_synonym: bacterium E3
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Yersinia pestis
type: Class
subclass of: Enterobacteriaceae
has_related_synonym: Bacillus pestis
has_related_synonym: Bacterium pestis
database_cross_reference: GC_ID:11
has_related_synonym: Pasteurella pestis
has_related_synonym: Pestisella pestis
has_related_synonym: Yersinia pseudotuberculosis subsp. pestis
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Vibrio cholerae
type: Class
subclass of: Gammaproteobacteria
has_related_synonym: Bacillo virgola del Koch
has_related_synonym: Bacillus cholerae
has_related_synonym: Bacillus cholerae-asiaticae
database_cross_reference: GC_ID:11
has_related_synonym: Kommabacillus
has_related_synonym: Liquidivibrio cholerae
has_related_synonym: Microspira comma
database_cross_reference: PMID:9272984
has_related_synonym: Pacinia cholerae-asiaticae
has_related_synonym: Spirillum cholerae
has_related_synonym: Spirillum cholerae-asiaticae
has_related_synonym: Vibrio choleae
has_related_synonym: Vibrio cholera
has_related_synonym: Vibrio cholerae-asiaticae
has_related_synonym: Vibrio comma
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ncbitaxon.owl
imported from: vo.owl

Vertebrata <Metazoa>
type: Class
subclass of: Bilateria
alternative term: Vertebrata
editor preferred term: Vertebrata <Metazoa>
alternative term: vertebrates
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl

Corynebacterineae
type: Class
subclass of: Bacteria
database_cross_reference: GC_ID:11
has_alternative_id: NCBITaxon:1761
database_cross_reference: PMID:11837321
database_cross_reference: PMID:1736962
database_cross_reference: PMID:19244447
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon suborder
imported from: ncbitaxon.owl
imported from: vo.owl

Salmonella enterica subsp. enterica serovar Typhi
type: Class
subclass of: Enterobacteriaceae
has_related_synonym: Bacillus typhi
has_related_synonym: Bacterium (subgen. Eberthella) typhi
database_cross_reference: GC_ID:11
has_alternative_id: NCBITaxon:41530
has_alternative_id: NCBITaxon:601
has_alternative_id: NCBITaxon:72667
database_cross_reference: PMID:10319519
database_cross_reference: PMID:10758910
database_cross_reference: PMID:15653930
database_cross_reference: PMID:16558776
database_cross_reference: PMID:9336938
has_related_synonym: Salmonella choleraesuis serovar Typhi
has_related_synonym: Salmonella choleraesuis typhi
has_related_synonym: Salmonella enterica ser. typhi
has_related_synonym: Salmonella enterica serotype Typhi
has_related_synonym: Salmonella enterica serovar Typhi
has_related_synonym: Salmonella typhi
has_obo_namespace: ncbi_taxonomy
imported from: ncbitaxon.owl
imported from: vo.owl

Bacilli
type: Class
subclass of: Firmicutes
has_related_synonym: Bacillus/Lactobacillus/Streptococcus group
has_related_synonym: Firmibacteria
database_cross_reference: GC_ID:11
database_cross_reference: PMID:20212322
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon class
imported from: ncbitaxon.owl
imported from: vo.owl

Homo sapiens
type: Class
subclass of: Euarchontoglires
subclass of: Bilateria
database_cross_reference: GC_ID:1
editor preferred term: Homo sapiens
has_exact_synonym: human
alternative term: human
alternative term: human being
has_exact_synonym: man
alternative term: man
has_obo_namespace: ncbi_taxonomy
has_rank: NCBITaxon species
imported from: ico.owl
imported from: ncbitaxon.owl
imported from: obi.owl
imported from: vo.owl

adverse event
type: Class
subclass of: process
editor note: Melanie Courtot and YH: More work is needed on how to restrict the scope of a term to be an 'adverse event', notably regarding temporal association. When is an appropirate time interval between a medical intervention and an adverse event observed? One week, one month, one year, or a lifetime? For some well-studied medical interventions (e.g., administration of many vaccines or drugs), we probably have a general idea. For many new interventions, we don't know much. In OAE, this issue is associated with defining the 'adverse event incubation time'.
alternative term: AE
editor note: YH: There has been discussion regarding whether the term 'side effect' is an alternative term for 'adverse event'. In AERO, the term 'AERO:adverse event' represents a subset of those adverse events for which causality has been established. In OAE, an adverse event for which causality has been established is called 'causal adverse event'.
definition: a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event.
editor note: YH: The main scope of OAE includes: (1) represent terms and relations in the area of adverse events, (2) assess possible associations between an adverse event and a medical intervention, particularly, identify any causal effect of a medical intervention to an adverse event; and (2) understand the mechanism (including molecular mechanisms) of causal adverse events.
definition source: WEB: http://www.ncbi.nlm.nih.gov/pubmed/25093068
comment: The OAE official website is: http://www.oae-ontology.org/.
definition source: WEB: http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm
alternative term: adverse reaction
editor note: YH: An adverse event is a process that has specified output of some adverse medical outcome (e.g., symptom, sign or accident) after a medical intervention (or process) (e.g., administration of drug or vaccine). The medical intervention can be an administration of a drug, a vaccine (i.e., vaccination), or a special nutritional product (for example, dietary supplement, infant formula, medical food), surgery, or usage of a medical device.
definition source: WEB: http://en.wikipedia.org/wiki/Adverse_event
editor note: YH: An adverse event is possibly induced by the medical intervention. It can be caused by the medical intervention, or may not be caused by the medical intervention. One ultimate goal (or the goal in clinics) of study adverse events is to assess if the adverse event outcome is due to the medical intervention.
term editor: Yongqun He
imported from: oae.owl

vaccine adverse event
type: Class
subclass of: adverse event
definition: an adverse event that occurs after a vaccination.
term editor: YH
imported from: oae.owl

dizziness AE
type: Class
subclass of: adverse event
see also: HPO: HP_0002321
see also: SIDER: C0012833
see also: MedDRA ID: 10013573
term editor: YH, SS, MW
definition: a sensory capability AE that has an outcome of dizziness
comment: Dizziness describes a number of subjective symptoms, which the patient may describe as feelings of lightheadedness, floating, wooziness, giddiness, confusion, disorientation or loss of balance. Medical terms include vertigo, disequilibrium, pre-syncope or syncoptic episode. Causes may stem from a variety of failures of equilibrioception, hypotension, cerebral hypoxia or a reaction to environmental chemicals or drugs.
imported from: oae.owl

syncope AE
type: Class
subclass of: adverse event
see also: SIDER: C0039070
see also: MedDRA: 10024855
definition: a sensory capability AE that has an outcome of loss of consciousness, fainting
definition source: WEB: http://en.wikipedia.org/wiki/Unconsciousness
alternative term: fainting
alternative term: Syncope is the medical term for fainting, a sudden, usually temporary, loss of consciousness.
term editor: YH, SS, MW
see also: HPO: HP_0001279
definition source: WEB: http://en.wikipedia.org/wiki/Syncope_%28medicine%29
imported from: oae.owl

Guillain-Barre syndrome AE
type: Class
subclass of: adverse event
see also: SIDER: C0018378
definition source: WEB: http://www.ncbi.nlm.nih.gov/pubmed/23299621
definition: a nervous system AE that has the symptom of GBS. Guillain-Barre syndrome (GBS) is a disorder in which the body's immune system attacks part of the peripheral nervous system. The first symptoms of this disorder include varying degrees of weakness or tingling sensations in the legs. In many instances, the weakness and abnormal sensations spread to the arms and upper body. These symptoms can increase in intensity until the muscles cannot be used at all and the patient is almost totally paralyzed. In these cases, the disorder is life-threatening and is considered a medical emergency. Usually Guillain-Barre occurs a few days or weeks after the patient has had symptoms of a respiratory or gastrointestinal viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. Reference: http://www.ninds.nih.gov/disorders/gbs/gbs.htm.
alternative term: GBS AE
term editor: YH, SS
see also: HPO: HP_0007131
see also: MedDRA: 10018767
see also: MedDRA ID: 10018767
imported from: oae.owl

serious adverse event
type: Class
subclass of: adverse event
alternative term: serious adverse event
definition source: WEB: http://www.google.ca/url?sa=t&source=web&ct=res&cd=1&ved=0CA4QFjAA&url=http%3A%2F%2Fwww.irrd.ca%2Fethics%2Fimages%2FAdverse-event-definition.doc&ei=eqFMS-yFNZSoswOt6siKAQ&usg=AFQjCNGnQcwI8OXH7dqxwo4RgZEEn8X6lg&sig2=UNngkCdO5ZTFvbIB1pKuaA
definition source: WEB: http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm
definition source: WEB: http://en.wikipedia.org/wiki/Serious_adverse_event
term editor: YH, MC
alternative term: severe adverse event
definition: serious adverse event is an adverse event that requires in-patient hospitalization, or prolongation of existing hospitalization, or that causes congenital malformation, or that results in persistent or significant disability or incapacity, or that is life threatening or results in death.
imported from: oae.owl

planned process
type: Class
equivalent class: Restriction
  on property: realizes
  some values from: Restriction
    on property: concretizes
    some values from: plan specification
subclass of: process
editor note: 'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)
curator notes: 6/11/9: Edited at workshop. Used to include: is initiated by an agent
term editor: Bjoern Peters
example of usage: Injecting mice with a vaccine in order to test its efficacy
definition source: branch derived
definition: A processual entity that realizes a plan which is the concretization of a plan specification.
curator notes: This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)
editor preferred term: planned process
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl
imported from: vo.owl

processed material
type: Class
subclass of: material entity
example of usage: Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples
definition: Is a material entity that is created or changed during material processing.
term editor: PERSON: Alan Ruttenberg
editor preferred term: processed material
has curation status: ready for release
imported from: obi.owl
imported from: vo.owl

investigation
type: Class
subclass of: planned process
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: planning
    intersection of: Restriction
      on property: has_specified_output
      some values from: study design
subclass of: Restriction
  on property: has part
  some values from: drawing a conclusion based on data
subclass of: Restriction
  on property: has part
  some values from: documenting
subclass of: Restriction
  on property: has part
  some values from: study design execution
curator notes: Could add specific objective specification
example of usage: Lung cancer investigation using expression profiling, a stem cell transplant investigation, biobanking is not an investigation, though it may be part of an investigation
ISA alternative term: study
term editor: Bjoern Peters
definition source: OBI branch derived
definition: a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).
editor preferred term: investigation
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

investigation agent role
type: Class
equivalent class: Class
  intersection of: role
  intersection of: Restriction
    on property: inheres in
    some values from: Restriction
      on property: bearer of
      some values from: Restriction
        on property: concretizes
        some values from: Restriction
subclass of: role
subclass of: Restriction
  on property: realized in
  all values from: investigation
curator notes: Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.
editor note: Implementing a study means carrying out or performing the study and providing reagents or other materials used in the study and other tasks without which the study would not happen.
editor preferred term: investigation agent role
alternative term: investigator
ISA alternative term: study person role
term editor: GROUP: Role Branch
definition source: OBI
editor note: Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable representing investigations run by robot scientists such as ADAM (King et al, Science, 2009)
comment: Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable investigations run by robot scientists such as ADAM (King et al, Science, 2009)
definition: A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing.
example of usage: The person perform microarray experiments and submit microarray results (including raw data, processed data) with experiment description to ArrayExpress.
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

organization
type: Class
subclass of: material entity
definition source: GROUP: OBI
term editor: PERSON: Alan Ruttenberg
term editor: PERSON: Bjoern Peters
term editor: PERSON: Philippe Rocca-Serra
term editor: PERSON: Susanna Sansone
definition: An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.
example of usage: PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods.
editor preferred term: organization
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

protocol
type: Class
subclass of: plan specification
ISA alternative term: study protocol
definition: A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.
definition source: OBI branch derived + wikipedia (http://en.wikipedia.org/wiki/Protocol_%28natural_sciences%29)
example of usage: PCR protocol, has objective specification, amplify DNA fragment of interest, and has action specification describes the amounts of experimental reagents used (e..g. buffers, dNTPS, enzyme), and the temperature and cycle time settings for running the PCR.
term editor: PlanAndPlannedProcess Branch
editor preferred term: protocol
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

material to be added role
type: Class
subclass of: role
curator notes: 9 March 09 from discussion with PA branch
definition source: OBI
term editor: Role Branch
example of usage: drug added to a buffer contained in a tube; substance injected into an animal;
editor preferred term: material to be added role
definition: material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process
has curation status: metadata complete
imported from: obi.owl
imported from: vo.owl

drawing a conclusion based on data
type: Class
subclass of: planned process
subclass of: Restriction
  on property: has_specified_input
  some values from: data item
subclass of: Restriction
  on property: has_specified_output
  some values from: conclusion based on data
definition source: Bjoern Peters
example of usage: Concluding that a gene is upregulated in a tissue sample based on the band intensity in a western blot. Concluding that a patient has a infection based on measurement of an elevated body temperature and reported headache. Concluding that there were problems in an investigation because data from PCR and microarray are conflicting. Concluding that 'defects in gene XYZ cause cancer due to improper DNA repair' based on data from experiments in that study that gene XYZ is involved in DNA repair, and the conclusion of a previous study that cancer patients have an increased number of mutations in this gene.
term editor: PERSON: Bjoern Peters
term editor: PERSON: Jennifer Fostel
definition: A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion
editor preferred term: drawing a conclusion based on data
has curation status: metadata complete
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

planning
type: Class
subclass of: process
subclass of: Class
  intersection of: process
  intersection of: Restriction
    on property: has participant
    some values from: plan specification
editor note: 7/18/2011 BP: planning used to itself be a planned process. Barry Smith pointed out that this would lead to an infinite regression, as there would have to be a plan to conduct a planning process, which in itself would be the result of planning etc. Therefore, the restrictions on 'planning' were loosened to allow for informal processes that result in an 'ad hoc plan '. This required changing from 'has_specified_output some plan specifiction' to 'has_participant some plan specification'.
term editor: Bjoern Peters
definition source: Bjoern Peters
definition source: Plans and Planned Processes Branch
example of usage: The process of a scientist thinking about and deciding what reagents to use as part of a protocol for an experiment. Note that the scientist could be human or a "robot scientist" executing software.
definition: a process of creating or modifying a plan specification
editor preferred term: planning
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

target of material addition role
type: Class
subclass of: role
editor note: From Branch discussion with BP, AR, MC -- there is a need for the recipient to interact with the administered material. for example, a tooth receiving a filling was not considered to be a target role.
term editor: GROUP: Role Branch
definition source: OBI
example of usage: peritoneum of an animal receiving an interperitoneal injection; solution in a tube receiving additional material; location of absorbed material following a dermal application.
editor preferred term: target of material addition role
definition: target of material addition role is a role realized by an entity into which a material is added in a material addition process
has curation status: metadata complete
imported from: obi.owl
imported from: vo.owl

study design execution
type: Class
equivalent class: Class
  intersection of: planned process
  intersection of: Restriction
    on property: realizes
    some values from: Restriction
      on property: concretizes
      some values from: study design
subclass of: planned process
curator notes: 6/11/9: edited at workshop. Used to be: study design execution is a process with the objective to generate data according to a concretized study design. The execution of a study design is part of an investigation, and minimally consists of an assay or data transformation.
definition: a planned process that realizes the concretization of a study design
definition source: branch derived
example of usage: injecting a mouse with PBS solution, weighing it, and recording the weight according to a study design.
editor note: removed axiom has_part some (assay or 'data transformation') per discussion on protocol application mailing list to improve reasoner performance. The axiom is still desired.
editor preferred term: study design execution
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

informed consent process
type: Class
subclass of: planned process
subclass of: Restriction
  on property: has_specified_input
  some values from: Homo sapiens
subclass of: Restriction
  on property: has participant
  some values from: Restriction
    on property: has role at some time
    some values from: consenter role
subclass of: Restriction
  on property: has_specified_input
  some values from: informed consent form
subclass of: Restriction
  on property: has participant
  some values from: Restriction
    on property: has role
    some values from: investigation agent role
editor note: 09/28/2009 Alan Ruttenberg: This is made a subclass of the higher level processual entity in BFO because I don't want to take a stand on whether it is a process aggregate. Analogous to the situation with Material entity.
curator notes: 2009/09/28 Alan Ruttenberg. Fucoidan-use-case
definition: A planned process in which a person or their legal representative is informed about key facts about potential risks and benefits of a process and makes a documented decision as to whether the person in question will participate.
term editor: Person:Alan Ruttenberg
definition source: http://clinicaltrials.gov/ct2/info/glossary#informed
editor preferred term: informed consent process
has curation status: metadata complete
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

questionnaire
type: Class
subclass of: document
editor note: Need to clarify if this is a document or a directive information entity (or what their connection is))
editor preferred term: questionnaire
definition: A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study.
definition source: Merriam-Webster
term editor: PERSON: Jessica Turner
has curation status: metadata complete
imported from: ico.owl
imported from: obi.owl

conclusion based on data
type: Class
subclass of: information content entity
subclass of: Restriction
  on property: is_specified_output_of
  some values from: drawing a conclusion based on data
subclass of: Restriction
  on property: is_supported_by_data
  some values from: data item
editor note: In the Philly 2013 workshop, we recognized the limitations of "conclusion textual entity", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate.
definition source: Group:2013 Philly Workshop group
editor preferred term: conclusion based on data
definition: An information content entity that is inferred from data.
term editor: Group:2013 Philly Workshop group
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl

organism
type: Class
equivalent class: Class
  union of: Viruses
  union of: Bacteria
  union of: Archaea
  union of: Eukaryota
subclass of: material entity
editor note: 10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')
term editor: GROUP: OBI Biomaterial Branch
definition: A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.
definition source: WEB: http://en.wikipedia.org/wiki/Organism
example of usage: animal
example of usage: fungus
editor preferred term: organism
example of usage: plant
example of usage: virus
has curation status: organizational term
has curation status: ready for release
imported from: ico.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

study design
type: Class
subclass of: plan specification
subclass of: Restriction
  on property: has part
  some values from: protocol
definition: A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.
editor note: Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available.
term editor: PERSON: Chris Stoeckert
example of usage: a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design.
alternative term: experimental design
curator notes: rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol.
editor preferred term: study design
has curation status: ready for release
has curation status: pending final vetting
imported from: ico.owl
imported from: obi.owl

genome of Bacteria
type: Class
subclass of: material entity
subclass of: Restriction
  on property: has part
  some values from: gene of Bacteria
subclass of: Restriction
  on property: is genome of organism
  some values from: Bacteria
organism NCBITaxon ID: 2
definition: The genome of an organism of Bacteria
term editor: Yue Liu, Bin Zhao, Oliver He
imported from: ogg.owl
imported from: vo.owl

genome of Proteobacteria
type: Class
subclass of: genome of Bacteria
subclass of: Restriction
  on property: has part
  some values from: gene of Proteobacteria
subclass of: Restriction
  on property: is genome of organism
  some values from: Proteobacteria
organism NCBITaxon ID: 1224
definition: The genome of an organism of Proteobacteria
term editor: Yue Liu, Bin Zhao, Oliver He
imported from: ogg.owl
imported from: vo.owl

gene of Bacteria
type: Class
subclass of: material entity
subclass of: Restriction
  on property: is gene of organism
  some values from: Bacteria
organism NCBITaxon ID: 2
definition: A gene of an organism of Bacteria
term editor: Yue Liu, Bin Zhao, Oliver He
imported from: ogg.owl
imported from: vo.owl

gene of Proteobacteria
type: Class
subclass of: gene of Bacteria
subclass of: Restriction
  on property: is gene of organism
  some values from: Proteobacteria
organism NCBITaxon ID: 1224
definition: A gene of an organism of Proteobacteria
term editor: Yue Liu, Bin Zhao, Oliver He
imported from: ogg.owl
imported from: vo.owl

age
type: Class
subclass of: quality
definition: A time quality inhering in a bearer by virtue of how long the bearer has existed.
id: PATO:0000011
has_obo_namespace: quality
imported from: pato.owl
in_subset: attribute slim
in_subset: scalar slim

biological sex
type: Class
subclass of: quality
definition: An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved.
id: PATO:0000047
has_obo_namespace: quality
imported from: pato.owl
in_subset: attribute slim

female
type: Class
subclass of: biological sex
definition: A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes.
id: PATO:0000383
has_obo_namespace: quality
imported from: pato.owl
in_subset: mpath slim
in_subset: value slim

male
type: Class
subclass of: biological sex
definition: A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes.
id: PATO:0000384
has_obo_namespace: quality
imported from: pato.owl
in_subset: mpath slim
in_subset: value slim

quality of a single physical entity
type: Class
subclass of: quality
definition: A physical object quality which inheres in a single-bearer.
editor preferred term: quality of a single physical entity
imported from: vo.owl
imported from: PATO

seizure
type: Class
subclass of: symptom
id: SYMP:0000124
has_exact_synonym: seizure
has_obo_namespace: symptoms
imported from: symp.owl

faint
type: Class
subclass of: symptom
definition: Faint is a alteration of consciousness characterized by a loss of consciousness because of a temporary decrease in the blood supply to the brain.
id: SYMP:0000445
has_exact_synonym: fainting
has_obo_namespace: symptoms
has_exact_synonym: syncope
imported from: symp.owl

symptom
type: Class
subclass of: quality of a single physical entity
definition: A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease.
id: SYMP:0000462
database_cross_reference: SyOID:14974
has_obo_namespace: symptoms
imported from: symp.owl

rash
type: Class
subclass of: symptom
definition: A skin and integumentary tissue symptom characterized as an eruption on the body typically with little or no elevation above the surface.
database_cross_reference: ICD9CM_2005:782.1
id: SYMP:0000487
database_cross_reference: SyOID:13022
database_cross_reference: UMLS_CUI:C0015230
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243780
has_exact_synonym: erythema
has_exact_synonym: rubor
has_exact_synonym: skin eruption
has_exact_synonym: skin rash
has_exact_synonym: skin redness
has_obo_namespace: symptoms
imported from: symp.owl

respiratory system and chest symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:786
id: SYMP:0000514
database_cross_reference: SyOID:5868
database_cross_reference: UMLS_CUI:C0476271
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284200
has_obo_namespace: symptoms
imported from: symp.owl

chest pain
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:786.5
database_cross_reference: ICD9CM_2005:786.50
id: SYMP:0000576
database_cross_reference: SyOID:4705
database_cross_reference: UMLS_CUI:C0008031
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243830
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0400627
has_obo_namespace: symptoms
imported from: symp.owl

convulsion
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:780.3
id: SYMP:0000596
database_cross_reference: SyOID:6961
database_cross_reference: UMLS_CUI:C0009951
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0042665
has_obo_namespace: symptoms
imported from: symp.owl

wheezing
type: Class
subclass of: respiratory system and chest symptom
database_cross_reference: ICD9CM_2005:786.07
id: SYMP:0000604
database_cross_reference: SyOID:7248
database_cross_reference: UMLS_CUI:C0043144
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0133941
definition: Wheezing is a respiratory abnormality characterized by breathing with difficulty usually with a whistling sound.
has_obo_namespace: symptoms
imported from: symp.owl

dizziness
type: Class
subclass of: symptom
definition: Dizziness is a neurological and physiological symptom characterized by a sensation of unsteadiness accompanied by a feeling of movement within the head.
database_cross_reference: ICD9CM_2005:780.4
id: SYMP:0000610
database_cross_reference: SyOID:7637
database_cross_reference: UMLS_CUI:C0476206
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243727
has_exact_synonym: dizzy
has_obo_namespace: symptoms
imported from: symp.owl

fever
type: Class
subclass of: symptom
definition: Fever is a neurological and physiological symptom characterized by a rise of body temperature above the normal whether a natural response (as to infection) or artificially induced for therapeutic reasons.
database_cross_reference: ICD9CM_2005:780.6
id: SYMP:0000613
database_cross_reference: SyOID:776
database_cross_reference: UMLS_CUI:C0015967
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0058972
has_exact_synonym: pyrexia
has_obo_namespace: symptoms
imported from: symp.owl

low-grade fever
type: Class
subclass of: fever
creation date: 2010-10-15T11:28:26Z
definition: Low-grade fever is a fever that does not exceed 38.5 degree centrigrade.
id: SYMP:0000879
created by: lschriml
has_obo_namespace: symptoms
imported from: symp.owl

high fever
type: Class
subclass of: fever
creation date: 2010-10-15T11:28:26Z
definition: High fever is a fever that involved an elevated temperature.
id: SYMP:0000882
created by: lschriml
has_obo_namespace: symptoms
imported from: symp.owl

vomiting
type: Class
subclass of: symptom
id: SYMP:0019145
definition: Vomiting is a digestive system symptom characterized by throwing up the stomach contents.
has_exact_synonym: emesis
has_obo_namespace: symptoms
imported from: symp.owl

dyspnea
type: Class
subclass of: respiratory system and chest symptom
definition: Dyspnea is a respiratory abnormality characterized by difficult or labored respiration.
id: SYMP:0019153
has_exact_synonym: breathing difficulty
has_exact_synonym: breathlessness
has_exact_synonym: difficulty breathing
has_exact_synonym: labored respiration
has_exact_synonym: shortness of breath
has_obo_namespace: symptoms
imported from: symp.owl

mouth
type: Class
subclass of: gross anatomical part
database_cross_reference: AAO:0010355
database_cross_reference: BTO:0001090
database_cross_reference: EFO:0000825
database_cross_reference: FBbt:00003126
database_cross_reference: FMA:49184
definition: First portion of the digestive tract[WP]. The portion of the digestive that develops from the stomodeum
database_cross_reference: GAID:75
database_cross_reference: MA:0002474
database_cross_reference: MAT:0000038
database_cross_reference: MESH:A.01.456.505.631
database_cross_reference: MIAA:0000038
database_cross_reference: OpenCyc:Mx4rvVidh5wpEbGdrcN5Y29ycA
database_cross_reference: TADS:0000040
database_cross_reference: TAO:0000547
database_cross_reference: TGMA:0000131
comment: TODO - check fly mouthpart. note in uberon we distinguish between the mouth and the oral opening. the mouth is part of the digestive tract. TODO - check isa parent subdivision of head - is it a subdivision of the head or digestive tract
id: UBERON:0000165
database_cross_reference: VHOG:0000812
database_cross_reference: XAO:0003029
database_cross_reference: ZFA:0000547
has_exact_synonym: adult mouth
has_related_synonym: cavitas oris
has_related_synonym: cavum oris
database_cross_reference: galen:Mouth
has_related_synonym: mouth cavity
has_related_synonym: oral vestibule
has_exact_synonym: regio oralis
has_related_synonym: rima oris
has_related_synonym: stoma
has_obo_namespace: uberon
has_related_synonym: vestibule of mouth
has_related_synonym: vestibulum oris
imported from: uberon.owl
imported from: vo.owl
in_subset: major organ
in_subset: uberon slim
in_subset: vertebrate core

skeletal muscle tissue
type: Class
subclass of: gross anatomical part
database_cross_reference: AAO:0011099
database_cross_reference: BTO:0001103
database_cross_reference: EFO:0000888
database_cross_reference: EHDAA2:0001842
database_cross_reference: EHDAA:2923
database_cross_reference: EHDAA:5035
database_cross_reference: EHDAA:5043
database_cross_reference: EHDAA:5978
database_cross_reference: EHDAA:5984
database_cross_reference: EHDAA:8277
database_cross_reference: EHDAA:8291
database_cross_reference: EHDAA:8326
database_cross_reference: EHDAA:9146
database_cross_reference: EV:0100377
database_cross_reference: FMA:14069
database_cross_reference: GAID:141
database_cross_reference: MA:0002439
database_cross_reference: MAT:0000302
database_cross_reference: MESH:A.02.633.567
database_cross_reference: MIAA:0000302
database_cross_reference: OpenCyc:Mx4rv2kf-5wpEbGdrcN5Y29ycA
database_cross_reference: SCTID:426215008
comment: TODO - add skeletal muscle organ? See GO:0060538 skeletal muscle organ development. Consider FBbt:00005073 - somatic muscle.
definition: Tissue which consists of skeletal muscle fibers surrounded by endomysium. Examples: Skeletal muscle tissue of biceps, Skeletal muscle tissue of diaphragm[FMA]. Striated muscle tissue under control of the somatic nervous system. It is one of three major muscle types, the others being cardiac and smooth muscle. As its name suggests, most skeletal muscle is attached to bones by bundles of collagen fibers known as tendons. Skeletal muscle is made up of individual components known as muscle fibers. These fibers are formed from the fusion of developmental myoblasts. The myofibers are long, cylindrical, multinucleated cells composed of actin and myosin myofibrils repeated as a sarcomere, the basic functional unit of the cell and responsible for skeletal muscle's striated appearance and forming the basic machinery necessary for muscle contraction. The term muscle refers to multiple bundles of muscle fibers held together by connective tissue[WP].
id: UBERON:0001134
has_alternative_id: UBERON:FMA_14069-MA_0002439
database_cross_reference: VHOG:0000319
database_cross_reference: XAO:0000174
database_cross_reference: ZFA:0005277
database_cross_reference: ncithesaurus:Skeletal_Muscle_Tissue
has_exact_synonym: skeletal muscle
has_related_synonym: skeletal muscle organ
has_related_synonym: skeletal muscle system
has_related_synonym: somatic muscle
has_obo_namespace: uberon
imported from: uberon.owl
imported from: vo.owl
in_subset: uberon slim
in_subset: vertebrate core

urinary bladder
type: Class
subclass of: gross anatomical part
database_cross_reference: AAO:0000623
database_cross_reference: BTO:0001418
database_cross_reference: EFO:0000290
database_cross_reference: EHDAA2:0000174
database_cross_reference: EHDAA:9328
database_cross_reference: EMAPA:18321
database_cross_reference: EV:0100098
database_cross_reference: FMA:15900
database_cross_reference: GAID:0000004
database_cross_reference: MA:0000380
database_cross_reference: MAT:0000122
database_cross_reference: MESH:A.05.810.161
database_cross_reference: MIAA:0000122
database_cross_reference: OpenCyc:Mx4rvVjMmZwpEbGdrcN5Y29ycA
definition: Organ with organ cavity which is continuous proximally with the right and left ureters and distally with the urethra.
database_cross_reference: SCTID:302512001
id: UBERON:0001255
has_alternative_id: UBERON:FMA_15900-FMA_7203-MA_0000368-MA_0000380-MIAA_0000118-MIAA_0000119-MIAA_0000122-WBbt_0005775-XAO_0000154-ZFA_0000529
database_cross_reference: VHOG:0000740
database_cross_reference: XAO:0000154
has_exact_synonym: bladder
comment: editor note: consider adding a 'bladder' grouping class
has_broad_synonym: excretory canal
database_cross_reference: galen:UrinaryBladder
database_cross_reference: ncithesaurus:Bladder
has_obo_namespace: uberon
imported from: uberon.owl
imported from: vo.owl
in_subset: major organ
in_subset: organ slim
in_subset: uberon slim

hypodermis
type: Class
subclass of: gross anatomical part
database_cross_reference: BTO:0004525
database_cross_reference: FMA:70544
database_cross_reference: FMA:9630
database_cross_reference: GAID:929
definition: Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA].
database_cross_reference: MESH:A.10.165.887
comment: Note that this class combines superficial fascia and hypodermis in FMA. Note also BTO has 'subcutis'
database_cross_reference: TAO:0001136
id: UBERON:0002072
has_alternative_id: UBERON:FMA_70544-MIAA_0000418-ZFA_0000117-ZFA_0001136
database_cross_reference: ZFA:0001136
has_exact_synonym: hypoderm
database_cross_reference: ncithesaurus:Superficial_Fascia
has_related_synonym: subcutaneous tissue
has_related_synonym: subcutis
has_exact_synonym: superficial fascia
has_exact_synonym: tela subcutanea
has_obo_namespace: uberon
has_exact_synonym: vertebrate hypodermis
imported from: uberon.owl
imported from: vo.owl
in_subset: uberon slim
in_subset: vertebrate core

skin of body
type: Class
subclass of: gross anatomical part
database_cross_reference: BTO:0001253
database_cross_reference: EFO:0000962
database_cross_reference: EHDAA2:0001844
database_cross_reference: EMAPA:17525
database_cross_reference: FMA:7163
database_cross_reference: MESH:A.17.815
definition: Nonparenchymatous organ that consists of the dermis and epidermis. Subdivisions of the skin surround various body parts; as a whole, the skin constitutes the external layer of the body. Examples: There is only one skin[FMA]. Surface structure that consists of the external membranous integument of the animal.
comment: Note that FMA uses 'skin' for the entire organ. XAO seems consistent. MA seems to use it analagously to zone of skin
database_cross_reference: OpenCyc:Mx4rvVjX3ZwpEbGdrcN5Y29ycA
database_cross_reference: SCTID:181469002
id: UBERON:0002097
has_alternative_id: UBERON:FMA_7163-MA_0000151-MIAA_0000284-XAO_0000023
database_cross_reference: XAO:0000023
has_exact_synonym: entire skin
database_cross_reference: galen:Skin
has_related_synonym: integument
database_cross_reference: ncithesaurus:Skin
has_related_synonym: skin
has_obo_namespace: uberon
imported from: uberon.owl
imported from: vo.owl
in_subset: major organ
in_subset: uberon slim

Manitoba vaccination informed consent form
type: Class
subclass of: vaccination informed consent form
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Manitoba vaccination consent
definition: A vaccination informed consent form that is provided by Manitoba government in Canada
creator: YL, YH

questionnaire for Manitoba vaccination consent
type: Class
subclass of: vaccination screening questionnaire
subclass of: Restriction
  on property: has component
  some values from: question on reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: allergy question
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question on any medication affecting blood clotting
subclass of: Restriction
  on property: has component
  some values from: question on long-term health problem
term editor: YH, YL
editor note: We may also model the Minatoba Child Informed Consent form: http://www.gov.mb.ca/health/publichealth/cdc/div/docs/7707.pdf
definition: a questionnaire that is part of the Manitoba vaccination informed consent form.

vaccination screening questionnaire
type: Class
subclass of: questionnaire
subclass of: Restriction
  on property: part of continuant at some time
  some values from: vaccination informed consent form
definition: A questionnaire that contains different questions of an intended vaccine reciepiant's health history, allergy history, and current condition, in order to assess the contraindication and precaution for administering a vaccine.
term editor: YL,JZ,YH

question whether allergic to vaccine component
type: Class
subclass of: allergy question
term editor: YL
definition: a question textual entity that asks whether the questionee is allergic to a vaccine component

don't know answer text entity
type: Class
subclass of: answer option text entity
creator: YL

questionnaire for Rite Aid vaccination consent
type: Class
subclass of: vaccination screening questionnaire
subclass of: Restriction
  on property: documented by
  has value: Rite Aid

filled questionnaire for Costco vaccination consent
type: Class
subclass of: questionnaire for Costco vaccination consent
subclass of: Restriction
  on property: is_specified_output_of
  some values from: filling questionnaire
term editor: YH, YL
definition: a questionnaire for Costco vaccination consent that is filled

filled questionnaire for Walgreens vaccination consent
type: Class
subclass of: questionnaire for Walgreens vaccination consent
subclass of: Restriction
  on property: is_specified_output_of
  some values from: filling questionnaire
term editor: YH, YL
definition: a questionnaire for Walgreens vaccination consent that is filled

questionnaire for Rite Aid vaccination consent in California
type: Class
subclass of: questionnaire for Rite Aid vaccination consent
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on long-term aspirin therapy
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: minor vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question on vaccination caused Guillain-Barre syndrome
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on wheezing history
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: 2-4 year old vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question on current anti-cancer drug usage
subclass of: Restriction
  on property: has component
  some values from: question on anemia
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question whether had Shingles vaccination
subclass of: Restriction
  on property: has component
  some values from: steroids treatment question
subclass of: Restriction
  on property: has component
  some values from: question on vaccination in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: question on long-term kidney disease
subclass of: Restriction
  on property: has component
  some values from: question whether bring imunization record card
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question on cancer, leukemia, AIDS or any other immune system problem
subclass of: Restriction
  on property: has component
  some values from: question on serious reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: question whether relate to new born infant
subclass of: Restriction
  on property: has component
  some values from: question whether had Tdap vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether had Pneumococcal vaccination
subclass of: Restriction
  on property: has component
  some values from: question on long-term metabolic disease
subclass of: Restriction
  on property: used in geographic location
  has value: State of California
subclass of: Restriction
  on property: has component
  some values from: question on long-term lung disease
subclass of: Restriction
  on property: has component
  some values from: question on blood or blood product transfusion, or immune (gamma) globulin in past year
subclass of: Restriction
  on property: has component
  some values from: question on seizure, brain, or nerve problem
subclass of: Restriction
  on property: has component
  some values from: question on asthma history
subclass of: Restriction
  on property: has component
  some values from: prednisone treatment question
subclass of: Restriction
  on property: has component
  some values from: question on long-term diabetes
subclass of: Restriction
  on property: has component
  some values from: X-ray treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to food
subclass of: Restriction
  on property: has component
  some values from: question on long-term heart disease
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to vaccine component
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on woman pregnancy now or during the next month
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: female vaccination patient

vaccination patient with asthma
type: Class
subclass of: vaccination patient

questionnaire for Rite Aid injectable flu vaccination consent in South Carolina
type: Class
subclass of: questionnaire for Rite Aid vaccination consent
subclass of: Restriction
  on property: used in geographic location
  has value: State of South Carolina
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on serious reaction after immunization
    intersection of: Restriction
      on property: is about vaccination procedure
      some values from: influenza vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether had Shingles vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to vaccine component
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: question whether diagnosed with Guillain-Barre syndrome
subclass of: Restriction
  on property: has component
  some values from: question whether had Tdap vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether bring imunization record card
subclass of: Restriction
  on property: has component
  some values from: question whether patient is older than 18 years old
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: injectable influenza vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question whether had Pneumococcal vaccination

questionnaire for Rite Aid non-flu vaccination consent in South Carolina
type: Class
subclass of: questionnaire for Rite Aid vaccination consent
subclass of: Restriction
  on property: has component
  some values from: question on asthma history
subclass of: Restriction
  on property: has component
  some values from: question whether had Pneumococcal vaccination
subclass of: Restriction
  on property: has component
  some values from: question on current anti-cancer drug usage
subclass of: Restriction
  on property: has component
  some values from: question whether relate to new born infant
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to vaccine component
subclass of: Restriction
  on property: has component
  some values from: question whether bring imunization record card
subclass of: Restriction
  on property: has component
  some values from: question on serious reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: question whether had Tdap vaccination
subclass of: Restriction
  on property: has component
  some values from: steroids treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: used in geographic location
  has value: State of South Carolina
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on woman pregnancy now or during the next month
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: female vaccination patient
subclass of: Restriction
  on property: has component
  some values from: question on vaccination caused disorder
subclass of: Restriction
  on property: has component
  some values from: question on vaccination caused Guillain-Barre syndrome
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question on cancer, leukemia, AIDS or any other immune system problem
subclass of: Restriction
  on property: has component
  some values from: question whether had Shingles vaccination
subclass of: Restriction
  on property: has component
  some values from: prednisone treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on long-term aspirin therapy
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: minor vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question on long-term lung disease
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to food
subclass of: Restriction
  on property: has component
  some values from: X-ray treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether smoke
subclass of: Restriction
  on property: has component
  some values from: question on long-term health problem
subclass of: Restriction
  on property: has component
  some values from: question on seizure, brain, or nerve problem
subclass of: Restriction
  on property: has component
  some values from: question on vaccination in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: question on blood or blood product transfusion, or immune (gamma) globulin in past year
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on wheezing history
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: 2-4 year old vaccination patient
        intersection of: Restriction

questionnaire for Rite Aid vaccination consent in other states than SC, NC and CA
type: Class
subclass of: questionnaire for Rite Aid vaccination consent
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on long-term aspirin therapy
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: minor vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: prednisone treatment question
subclass of: Restriction
  on property: has component
  some values from: steroids treatment question
subclass of: Restriction
  on property: has component
  some values from: question on vaccination caused Guillain-Barre syndrome
subclass of: Restriction
  on property: has component
  some values from: question on vaccination caused disorder
subclass of: Restriction
  on property: has component
  some values from: X-ray treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to vaccine component
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on wheezing history
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: 2-4 year old vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to food
subclass of: Restriction
  on property: has component
  some values from: question whether smoke
subclass of: Restriction
  on property: has component
  some values from: question whether relate to new born infant
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: has component
  some values from: question whether had Tdap vaccination
subclass of: Restriction
  on property: has component
  some values from: question on long-term health problem
subclass of: Restriction
  on property: has component
  some values from: question whether bring imunization record card
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on woman pregnancy now or during the next month
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: female vaccination patient
subclass of: Restriction
  on property: has component
  some values from: question on current anti-cancer drug usage
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question on cancer, leukemia, AIDS or any other immune system problem
subclass of: Restriction
  on property: has component
  some values from: question on seizure, brain, or nerve problem
subclass of: Restriction
  on property: has component
  some values from: question whether had Shingles vaccination
subclass of: Restriction
  on property: has component
  some values from: question on asthma history
subclass of: Restriction
  on property: has component
  some values from: question on long-term lung disease
subclass of: Restriction
  on property: has component
  some values from: question on vaccination in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: question whether had Pneumococcal vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question on serious reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: question on blood or blood product transfusion, or immune (gamma) globulin in past year

vaccination patient
type: Class
subclass of: Homo sapiens
subclass of: Restriction
  on property: participates_in
  some values from: vaccination
comment: After the vaccination process, this vaccination patient will bear the role of human vaccinee, and become a human vaccinee.
comment: If the patient is a minor, his/her legal representative will answer the screening question for him/her.
definition: a human who is going to recieve an administration of a vaccine, who bears a vaccination patient role, which is realized when he/she sits in a vaccination provider's site and is the bject of screening questions for receiving a vaccine.

legal representative of minor vaccination patient
type: Class
subclass of: Homo sapiens

Costco vaccination informed consent form
type: Class
subclass of: vaccination informed consent form
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Costco vaccination consent
subclass of: Restriction
  on property: documented by
  has value: Costco
subclass of: Restriction
  on property: used in geographic location
  has value: United States of America
definition: A vaccination informed consent form that is provided by Costco
term editor: YH, YL

Walgreens vaccination informed consent form
type: Class
subclass of: vaccination informed consent form
subclass of: Restriction
  on property: used in geographic location
  has value: United States of America
subclass of: Restriction
  on property: documented by
  has value: Walgreens
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Walgreens vaccination consent
definition: A vaccination informed consent form that is provided by Walgreens
term editor: YH, YL

questionnaire for Walgreens vaccination consent
type: Class
subclass of: vaccination screening questionnaire
subclass of: Restriction
  on property: has component
  some values from: question on home infusion
subclass of: Restriction
  on property: has component
  some values from: question on whether fainted or felt dizzy after immunization
subclass of: Restriction
  on property: has component
  some values from: X-ray treatment question
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on asthma or wheezing history
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: 5 year and younger vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on current antibiotics usage
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: used in geographic location
  has value: United States of America
subclass of: Restriction
  on property: has component
  some values from: question on weekly injection of etanercept
subclass of: Restriction
  on property: has component
  some values from: question on high-dose methotrexate usage
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to vaccine
subclass of: Restriction
  on property: has component
  some values from: question on CSF leak
subclass of: Restriction
  on property: has component
  some values from: question on cochlear implant
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on history of thrombocytopenia or thrombocytopenic purpura
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick with a moderate to high fever, vomiting/diarrhea
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on woman pregnancy
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: female vaccination patient
subclass of: Restriction
  on property: has component
  some values from: question on blood transfusion in past year
subclass of: Restriction
  on property: documented by
  has value: Walgreens
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on serious nasal condition
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question on leukemia
subclass of: Restriction
  on property: has component
  some values from: question on high-dose steroid therapy for longer than 2 weeks
subclass of: Restriction
  on property: has component
  some values from: question on weekly injection of infliximab
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on thymus disease
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question on cancer
subclass of: Restriction
  on property: has component
  some values from: question on azathioprine or 6-mercaptopurine usage
subclass of: Restriction
  on property: has component
  some values from: question on TB skin test in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question whether recieving aspirin-containing therapy
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: minor vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: seizure disorder question
subclass of: Restriction
  on property: has component
  some values from: question on weekly injection
subclass of: Restriction
  on property: has component
  some values from: question on asplenia
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on current anti-malarial medication
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: Class
        intersection of: vaccination patient
        intersection of: Restriction
subclass of: Restriction
  on property: has component
  some values from: question on weekly injection of adalmumab
subclass of: Restriction
  on property: has component
  some values from: question on vaccination in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: question on current aspirin medication
definition: a questionnaire that is part of the Walgreens vaccination informed consent form.
term editor: YH, YL

questionnaire for Costco vaccination consent
type: Class
subclass of: vaccination screening questionnaire
subclass of: Restriction
  on property: has component
  some values from: immunocompromisation question
subclass of: Restriction
  on property: has component
  some values from: question on long-term heart disease
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to vaccine
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: seizure disorder question
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question on reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: question on asthma or wheezing history
subclass of: Restriction
  on property: used in geographic location
  has value: United States of America
subclass of: Restriction
  on property: has component
  some values from: question on vaccination in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on woman pregnancy
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: female vaccination patient
subclass of: Restriction
  on property: has component
  some values from: X-ray treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: cortisone treatment question
subclass of: Restriction
  on property: has component
  some values from: question on blood transfusion in past year
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to food
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: has component
  some values from: question on cancer
subclass of: Restriction
  on property: documented by
  has value: Costco
subclass of: Restriction
  on property: has component
  some values from: question on leukemia
term editor: YH, YL
definition: a questionnaire that is part of the Costco vaccination informed consent form.

minor vaccination patient
type: Class
subclass of: vaccination patient
definition: a vaccination patient who is under the age of legal competence.According to US Civil Law, which described a person under a certain age as less than so many years. In most states, a person is no longer a minor after reaching the age of 18.
definition source: https://en.wikipedia.org/wiki/Minor_(law)
definition source: http://legal-dictionary.thefreedictionary.com/minor

female vaccination patient
type: Class
subclass of: vaccination patient
subclass of: Restriction
  on property: has gender
  some values from: female

flumist vaccination
type: Class
subclass of: intranasal influenza vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Class
    union of: FluMist
    union of: FluMist Quadrivalent

Rite Aid vaccination informed consent form
type: Class
subclass of: vaccination informed consent form
subclass of: Restriction
  on property: documented by
  has value: Rite Aid
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Rite Aid vaccination consent

pneumococcal vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Streptococcus pneumoniae vaccine

shingles vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Varicella-zoster virus vaccine
has synonym: Zoster vaccination

Tdap vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Diphtheria-Tetanus-Pertussis vaccine

vaccination patient over 65 years old
type: Class
subclass of: vaccination patient

questionnaire for Rite Aid vaccination consent in North Carolina
type: Class
subclass of: questionnaire for Rite Aid vaccination consent
subclass of: Restriction
  on property: has component
  some values from: question on asthma history
subclass of: Restriction
  on property: has component
  some values from: question on vaccination caused disorder
subclass of: Restriction
  on property: has component
  some values from: question on blood or blood product transfusion, or immune (gamma) globulin in past year
subclass of: Restriction
  on property: has component
  some values from: question on TB skin test in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: question whether had Tdap vaccination
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question whether react to triple antibiotic ointment
    intersection of: Restriction
      on property: is about vaccination procedure
      some values from: shingles vaccination
subclass of: Restriction
  on property: has component
  some values from: X-ray treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: has component
  some values from: prednisone treatment question
subclass of: Restriction
  on property: has component
  some values from: question on cancer, leukemia, AIDS or any other immune system problem
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on whether having cut, injury, puncture or open wound
    intersection of: Restriction
      on property: is about vaccination procedure
      some values from: Class
        union of: Tdap vaccination
        union of: Td vaccination
subclass of: Class
  intersection of: Restriction
    on property: has component
    some values from: question whether had Pneumococcal vaccination
  intersection of: Restriction
    on property: asking vaccination patient
    some values from: Class
      intersection of: vaccination patient over 65 years old
      intersection of: Class
        union of: vaccination patient with asthma
        union of: vaccination patient with COPD
        union of: vaccination patient with smoking habit
subclass of: Restriction
  on property: has component
  some values from: question on vaccination in past 4 weeks
subclass of: Restriction
  on property: has component
  some values from: question on vaccination caused Guillain-Barre syndrome
subclass of: Restriction
  on property: has component
  some values from: question on antiviral drug usage
subclass of: Restriction
  on property: has component
  some values from: question on long-term health problem
subclass of: Restriction
  on property: has component
  some values from: question whether diagnosed with ankylosing spondylitis
subclass of: Restriction
  on property: has component
  some values from: question whether diagnosed with rheumatoid arthritis
subclass of: Restriction
  on property: has component
  some values from: steroids treatment question
subclass of: Restriction
  on property: has component
  some values from: question on long-term lung disease
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question on current anti-cancer drug usage
subclass of: Restriction
  on property: has component
  some values from: question on health provider precaution or warning of specific vaccination
subclass of: Restriction
  on property: has component
  some values from: question on seizure, brain, or nerve problem
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question on serious reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: question whether bring imunization record card
subclass of: Restriction
  on property: has component
  some values from: question whether diagnosed with Crohn’s disease
subclass of: Restriction
  on property: used in geographic location
  has value: State of North Carolina
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question whether allergic to gelatin
    intersection of: Restriction
      on property: is about vaccination procedure
      some values from: shingles vaccination
subclass of: Restriction
  on property: has component
  some values from: question on faintig after vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether had Shingles vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to food
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on woman pregnancy now or during the next month
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: female vaccination patient
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to vaccine component

Td vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Diphtheria-Tetanus vaccine

vaccination patient with COPD
type: Class
subclass of: vaccination patient

vaccination patient with smoking habit
type: Class
subclass of: vaccination patient

2-4 year old vaccination patient
type: Class
subclass of: 5 year and younger vaccination patient

parent of minor vaccination patient
type: Class
subclass of: Homo sapiens

influenza vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Influenza virus vaccine

injectable influenza vaccination
type: Class
subclass of: influenza vaccination

intranasal influenza vaccination
type: Class
equivalent class: Class
  intersection of: influenza vaccination
  intersection of: intranasal vaccination
subclass of: influenza vaccination

Rite Aid injectable flu vaccination informed consent form in South Carolina
type: Class
subclass of: Rite Aid vaccination informed consent form
subclass of: Restriction
  on property: used in geographic location
  has value: State of South Carolina
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Rite Aid injectable flu vaccination consent in South Carolina

Rite Aid non-flu vaccination informed consent form in South Carolina
type: Class
subclass of: Rite Aid vaccination informed consent form
subclass of: Restriction
  on property: used in geographic location
  has value: State of South Carolina
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Rite Aid non-flu vaccination consent in South Carolina

Rite Aid vaccination informed consent form in California
type: Class
subclass of: Rite Aid vaccination informed consent form
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Rite Aid vaccination consent in California
subclass of: Restriction
  on property: used in geographic location
  has value: State of California

Rite Aid vaccination informed consent form in North Carolina
type: Class
subclass of: Rite Aid vaccination informed consent form
subclass of: Restriction
  on property: used in geographic location
  has value: State of North Carolina
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Rite Aid vaccination consent in North Carolina

Rite Aid vaccination informed consent form in other states than SC, NC and CA
type: Class
subclass of: Rite Aid vaccination informed consent form
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Rite Aid vaccination consent in other states than SC, NC and CA

Manitoba Seasonal Influenza and Pneumococcal vaccination informed consent form
type: Class
subclass of: Manitoba vaccination informed consent form
subclass of: Restriction
  on property: has part
  some values from: questionare for Manitoba Seasonal Influenza and Pneumococcal vaccination consent

Manitoba child immunization consent form
type: Class
subclass of: Manitoba vaccination informed consent form
subclass of: Restriction
  on property: has part
  some values from: questionnaire for Manitoba child immunization consent

questionnaire for Manitoba child immunization consent
type: Class
subclass of: questionnaire for Manitoba vaccination consent
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on reaction after immunization
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: minor vaccination patient
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question whether had Shingles vaccination
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: minor vaccination patient
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on woman pregnancy now or during the next month
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: minor vaccination patient
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on health condition requires doctor visit
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: minor vaccination patient
subclass of: Restriction
  on property: asking vaccination patient
  all values from: minor vaccination patient
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: allergy question
    intersection of: Restriction
      on property: asking vaccination patient
      some values from: minor vaccination patient

yellow fever vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Yellow fever virus vaccine

MMR vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Measles-Mumps-Rubella vaccine

typhoid vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Salmonella typhi vaccine

oral typhoid vaccination
type: Class
subclass of: typhoid vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: typhoid live oral vaccine

live vaccine vaccination
type: Class
subclass of: vaccination

University of Maryland College Park vaccination informed consent form
type: Class
subclass of: vaccination informed consent form
subclass of: Restriction
  on property: documented by
  has value: University of Maryland, College Park

questionnaire for University of Maryland College Park vaccination consent
type: Class
subclass of: vaccination screening questionnaire
subclass of: Restriction
  on property: documented by
  has value: University of Maryland, College Park

UM College Park injectable influenza vaccination informed consent
type: Class
subclass of: University of Maryland College Park vaccination informed consent form
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: injectable influenza vaccination

UM College Park flumist vaccination informed consent
type: Class
subclass of: University of Maryland College Park vaccination informed consent form
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: flumist vaccination

UM College Park Smallpox vaccination informed consent form
type: Class
subclass of: University of Maryland College Park vaccination informed consent form

questionnaire for UM College Park flumist vaccination consent
type: Class
subclass of: questionnaire for University of Maryland College Park vaccination consent
subclass of: Restriction
  on property: has component
  some values from: question whether in contact with severely immunocompromised person
subclass of: Restriction
  on property: has component
  some values from: question on asthma history
subclass of: Restriction
  on property: has component
  some values from: question on reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: question on fever
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: flumist vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg products
subclass of: Restriction
  on property: has component
  some values from: question whether diagnosed with Guillain-Barre syndrome
subclass of: Restriction
  on property: has component
  some values from: question on AIDS
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: question on stroke leading brain or nerve damage
subclass of: Restriction
  on property: has component
  some values from: question on convulsion leading brain or nerve damage
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: has component
  some values from: question on respiratory illness

questionnaire for UM College Park injectable influenza vaccination consent
type: Class
subclass of: questionnaire for University of Maryland College Park vaccination consent
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: injectable influenza vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to medication
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to thimerosal
subclass of: Restriction
  on property: has component
  some values from: question on woman's possibility of geting pregnant
subclass of: Restriction
  on property: has component
  some values from: question on fever
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg products
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question whether diagnosed with Guillain-Barre syndrome
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question on reaction after immunization

screening questionnaire for UM College Park smallpox vaccination consent
type: Class
subclass of: questionnaire for University of Maryland College Park vaccination consent
subclass of: Restriction
  on property: has component
  some values from: question on current medication usage
subclass of: Restriction
  on property: has component
  some values from: prednisone treatment question
subclass of: Restriction
  on property: has component
  some values from: question onwhether having skin rash
subclass of: Restriction
  on property: has component
  some values from: question on woman pregnancy now or during the next month
subclass of: Restriction
  on property: has component
  some values from: question on SLE
subclass of: Restriction
  on property: has component
  some values from: question whether live with a child less than one year old
subclass of: Restriction
  on property: has component
  some values from: question on whethere having severe burn
subclass of: Restriction
  on property: has component
  some values from: question whether having chickenpox
subclass of: Restriction
  on property: has component
  some values from: question on whether having impetigo
subclass of: Restriction
  on property: has component
  some values from: question on leukemia
subclass of: Restriction
  on property: has component
  some values from: question whether had organ transplant
subclass of: Restriction
  on property: has component
  some values from: question on whether diagnosed with congestive heart failure
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to polymixin B
subclass of: Restriction
  on property: has component
  some values from: question on stroke leading brain or nerve damage
subclass of: Restriction
  on property: has component
  some values from: question on lymphoma
subclass of: Restriction
  on property: has component
  some values from: question on whether having herpes
subclass of: Restriction
  on property: has component
  some values from: question on whether diagnosed with angina
subclass of: Restriction
  on property: has component
  some values from: question on AIDS
subclass of: Restriction
  on property: has component
  some values from: question on sexual intercourse without effecctive birth control after the vaccination
subclass of: Restriction
  on property: has component
  some values from: question on current anti-cancer drug usage
subclass of: Restriction
  on property: has component
  some values from: question whethere allergic to neomycin
subclass of: Restriction
  on property: has component
  some values from: question on cancer
subclass of: Restriction
  on property: has component
  some values from: question on long-term heart disease
subclass of: Restriction
  on property: has component
  some values from: question on woman's possibility of geting pregnant
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to streptomycin
subclass of: Restriction
  on property: has component
  some values from: steroids treatment question
subclass of: Restriction
  on property: has component
  some values from: question whether current breast-feeding
subclass of: Restriction
  on property: has component
  some values from: question on whether diagnosed with myocardial infarction
subclass of: Restriction
  on property: has component
  some values from: question on whether having psoriasis
subclass of: Restriction
  on property: has component
  some values from: question on last month's sexual intercourse without effecctive birth control
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question whethere allergic to chlortetracycline
subclass of: Restriction
  on property: has component
  some values from: question on Darier's disease
subclass of: Restriction
  on property: has component
  some values from: question on agammaglobulinemia
subclass of: Restriction
  on property: has component
  some values from: question on whether using steroid eye drop
subclass of: Restriction
  on property: has component
  some values from: question on current condition leads to skin break
subclass of: Restriction
  on property: has component
  some values from: question on whether having atopic dermatitis
subclass of: Restriction
  on property: has component
  some values from: question on chest pain
subclass of: Restriction
  on property: has component
  some values from: question on drug usage after organ transplant
subclass of: Restriction
  on property: has component
  some values from: Class
    intersection of: question on AIDS
    intersection of: question for household memeber of vaccination patient
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to smallpox vaccine
subclass of: Restriction
  on property: has component
  some values from: question on whether having shingles
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to latex
subclass of: Restriction
  on property: has component
  some values from: question on whether had transient ischemic attack
subclass of: Restriction
  on property: has component
  some values from: question on whether diagnosed with cardiomyopathy
subclass of: Restriction
  on property: has component
  some values from: question on autoimmune disease drug usage
subclass of: Restriction
  on property: has component
  some values from: question on shortness of breath when exert
subclass of: Restriction
  on property: has component
  some values from: question on whether having severe acne
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: smallpox vaccination

smallpox vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: has_specified_input
  some values from: Smallpox virus vaccine

household member of vaccination patient
type: Class
subclass of: Homo sapiens
term editor: YL
definition: a person lives in the same house with vaccination patient

close physical contact person of vaccination patient
type: Class
subclass of: Homo sapiens
term editor: YL
definition: a person who has close physical contact with the vaccination patient, such as sex partner

newborn infant
type: Class
subclass of: Homo sapiens
definition: A newborn infant, or neonate, is a child under 28 days of age.
NC ithesaurus: NCI: C16731
database_cross_reference: NCI: C16731
definition source: WHO (http://www.who.int/topics/infant_newborn/en/)
term editor: YL

vaccination informed consent process
type: Class
subclass of: informed consent process

question whether currently sick
type: Class
subclass of: current health condition question
subclass of: Restriction
  on property: is about
  some values from: sickness
comment: 1. Are you sick today? There is no evidence that acute illness reduces vaccine efficacy or increases vaccine adverse events (1). However, as a precaution with moderate or severe acute illness, all vaccines should be delayed until the illness has improved. Mild illnesses (such as upper respiratory infections or diarrhea) are NOT contraindications to vaccination. Do not withhold vaccination if a person is taking antibiotics. (http://www.immunize.org/catg.d/p4065.pdf)
has_exact_synonym: Are you sick today
definition: a question textual entity that asks whether the questionee is currently sick.
database_cross_reference: LOINC:66373-2
term editor: YL, YH

allergy question
type: Class
subclass of: question textual entity
subclass of: Restriction
  on property: is about
  some values from: hypersensitivity reaction type I disease
definition: a question textual entity that asks whether the questionee is allergic to some material.
term editor: YL, YH
comment: 2. Do you have allergies to medications, food, a vaccine component, or latex? If a person has anaphylaxis after eating gelatin, do not administer MMR,varicella, standard trivalent Fluzone, Flumist, rabies (Rabavert), oral typhoid, or yellow fever vaccine. A local reaction to a prior vaccine dose or vaccine components (e.g., latex) is not a contraindication to a subsequent dose or vaccine containing that component. For a table of vaccines supplied in vials or syringes that contain latex, go to www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/latex-table.pdf. For an extensive list of vaccine components, see reference 2. An egg-free recombinant influenza vaccine (RIV3) may be used in people age 18 years and older with egg allergy of any severity who have no other contraindications. People younger than age 18 years who have experienced a serious systemic or anaphylactic reaction (e.g., hives, swelling of the lips or tongue, acute respiratory distress, or collapse) after eating eggs can usually be vaccinated with inactivated influenza vaccine (IIV); consult ACIP recommendations (see reference 3). 2. Table of Vaccine Components: www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf. 3. CDC. Prevention and control of influenza with vaccines:Recommendations of the Advisory Committee on Immunization Practices (ACIP), United States, 2015–16 Influenza Season at www.cdc.gov/mmwr/pdf/wk/mm6430.pdf, pages 818–825 http://www.immunize.org/catg.d/p4065.pdf

question whether allergic to latex
type: Class
subclass of: allergy question
definition: a question textual entity that asks whether the questionee is allergic to latex.
term editor: YL, YH

question whether allergic to food
type: Class
subclass of: allergy question
subclass of: Restriction
  on property: is about
  some values from: food allergy
term editor: YL, YH
definition: a question textual entity that asks whether the questionee is allergic to food

question whether allergic to egg
type: Class
subclass of: question whether allergic to food
subclass of: Restriction
  on property: is about
  some values from: egg allergy
definition: a question textual entity that asks whether the questionee is allergic to food
term editor: YL, YH

question whether allergic to medication
type: Class
subclass of: allergy question
definition: a question textual entity that asks whether the questionee is allergic to a medication
term editor: YL, YH

question whether allergic to vaccine
type: Class
subclass of: allergy question
term editor: YL, YH
definition: a question textual entity that asks whether the questionee is allergic to a vaccine

question on reaction after immunization
type: Class
subclass of: question on past vaccination information
subclass of: Restriction
  on property: is about
  some values from: vaccine adverse event
term editor: YL, YH
definition: a question textual entity that asks whether the questionee had any reaction after a vaccination (i.e., immunization) in the past.

seizure disorder question
type: Class
subclass of: question on seizure, brain, or nerve problem
subclass of: Restriction
  on property: is about
  some values from: seizure
definition: a question textual entity that asks whether the questionee has experienced any seizure disorder
term editor: YL, YH

immunocompromisation question
type: Class
subclass of: question textual entity
subclass of: Restriction
  on property: is about
  some values from: immunocompromised condition
definition: a question textual entity that asks whether the vaccination patient is immunocomprised
term editor: YL, YH

question on woman pregnancy
type: Class
subclass of: question for woman
subclass of: Restriction
  on property: is about
  some values from: pregancy
definition: a question textual entity that asks whether a woman is pregnant now
term editor: YL, YH

current treatment question
type: Class
subclass of: question textual entity
definition: a question textual entity that asks whether the questionee is currently under any treatment
term editor: YL, YH

cortisone treatment question
type: Class
subclass of: steroids treatment question
term editor: YL, YH
definition: a current treatment question that asks whether the questionee is currently under any cortisone treatment

X-ray treatment question
type: Class
subclass of: immunocompromisation question
subclass of: current treatment question
definition: a current treatment question that asks whether the questionee is currently under any X-ray treatment
term editor: YL, YH

question on vaccination in past 4 weeks
type: Class
subclass of: question on past vaccination information
term editor: YL, YH
definition: a question textual entity that asks whether the questionee has been vaccinated in the past four weeks

question on TB skin test in past 4 weeks
type: Class
subclass of: previous medical precedure question
term editor: YL, YH
definition: a question textual entity that asks whether the questionee has conducted a TB skin test in the past four weeks

question on blood transfusion in past year
type: Class
subclass of: question on blood or blood product transfusion, or immune (gamma) globulin in past year
definition: a question textual entity that asks whether the questionee has conducted a blood transfusion in the past year
term editor: YL, YH

question on high-dose steroid therapy for longer than 2 weeks
type: Class
subclass of: steroids treatment question
term editor: YL, YH
definition: a current treatment question that asks whether the questionee has been under a high-dose steroid therapy ((prednisone > 20mg/day or equivalent)) for longer than two weeks

question on thymus disease
type: Class
subclass of: current health condition question
subclass of: Restriction
  on property: is about
  some values from: thymus gland disease
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: yellow fever vaccination
definition: a question textual entity that asks whether the questionee has a thymus disease
comment: This question is needed for yellow fever vaccination
term editor: YL, YH

question on current antibiotics usage
type: Class
subclass of: question on current medication usage
term editor: YL, YH
definition: a question textual entity that asks whether the questionee is currently taking some antibiotics
comment: This question is needed for oral typhoid vaccination

question on thrombocytopenia history
type: Class
subclass of: question on history of thrombocytopenia or thrombocytopenic purpura
subclass of: Restriction
  on property: is about
  some values from: thrombocytopenia
definition: a question textual entity that asks whether the questionee has a history of thrombocytopenia
term editor: YL, YH

question on current aspirin medication
type: Class
subclass of: question on current antibiotics usage
comment: This question is needed for oral typhoid vaccination
term editor: YL, YH
definition: a question textual entity that asks whether the questionee is currently taking aspirin

question on asthma or wheezing history
type: Class
subclass of: current health condition question
definition: a question textual entity that asks whether the questionee has a history of asthma or wheezing
term editor: YL, YH

question on serious nasal condition
type: Class
subclass of: current health condition question
term editor: YL, YH
definition: a question textual entity that asks whether the questionee has a serious nasal condition, which makes breathing difficult, such as a very stuffy nose.

question on long-term health problem
type: Class
subclass of: question on health condition requires doctor visit
definition: a question textual entity that asks whether the questionee has a a long-term health problem with heart disease, lung disease, asthma, kidney disease, metabolic disease (e.g., diabetes), anemia or other blood disorder.
term editor: YL, YH

question on long-term heart disease
type: Class
subclass of: question on long-term health problem
subclass of: Restriction
  on property: is about
  some values from: heart disease
term editor: YL, YH
definition: a question on long-term health problem that asks whether the questionee has a long-term heart disease

question on cancer
type: Class
subclass of: question on cancer, leukemia, AIDS or any other immune system problem
subclass of: Restriction
  on property: is about
  some values from: cancer
term editor: YL, YH
definition: a question on long-term health problem that asks whether the questionee has cancer

question on leukemia
type: Class
subclass of: question on cancer
subclass of: Restriction
  on property: is about
  some values from: leukemia
definition: a question on long-term health problem that asks whether the questionee has leukemia
term editor: YL, YH

question on long-term lung disease
type: Class
subclass of: question on long-term health problem
subclass of: Restriction
  on property: is about
  some values from: lung disease
creator: YL, YH
definition: a question on long-term health problem that asks whether the questionee has a long-term lung disease

filled questionnaire for Manitoba Seasonal Influenza and Pheumococcal vaccination consent
type: Class
subclass of: questionare for Manitoba Seasonal Influenza and Pneumococcal vaccination consent
subclass of: Restriction
  on property: is_specified_output_of
  some values from: filling questionnaire
subclass of: Restriction
  on property: has component
  some values from: allergy question
subclass of: Restriction
  on property: has component
  some values from: question whether allergic to egg
subclass of: Restriction
  on property: has component
  some values from: question on long-term health problem
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
subclass of: Restriction
  on property: has component
  some values from: question on any medication affecting blood clotting
subclass of: Restriction
  on property: has component
  some values from: question on reaction after immunization
definition: a questionnaire that is part of the Manitoba vaccination informed consent form.
creator: YL,YH

question on long-term metabolic disease
type: Class
subclass of: question on long-term health problem
definition: a question on long-term health problem that asks whether the questionee has a long-term metabolic disease

question on long-term diabetes
type: Class
subclass of: question on long-term metabolic disease
subclass of: Restriction
  on property: is about
  some values from: diabetes mellitus
creator: YL,YH
definition: a question on long-term health problem that asks whether the questionee has diabetes

question on anemia
type: Class
subclass of: question on long-term health problem
subclass of: Restriction
  on property: is about
  some values from: anemia
creator: YL,YH
definition: a question on long-term health problem that asks whether the questionee has anemia

question on AIDS
type: Class
subclass of: question on cancer, leukemia, AIDS or any other immune system problem
subclass of: Restriction
  on property: is about
  some values from: acquired immunodeficiency syndrome
creator: YL,YH
definition: a question on long-term health problem that asks whether the questionee has AIDS

prednisone treatment question
type: Class
subclass of: steroids treatment question
creator: YL,YH
definition: a current treatment question that asks whether the questionee is currently under prednisone treatment

steroids treatment question
type: Class
subclass of: current treatment question
subclass of: question on immunosuppressive drug usage
creator: YL,YH
definition: a current treatment question that asks whether the questionee is currently under any steroid treatment

question on current anti-cancer drug usage
type: Class
subclass of: question on cancer treatment
definition: YL,YH
definition: a question textual entity that asks whether the questionee is currently taking any anti-cancer drugs

question on whether fainted or felt dizzy after immunization
type: Class
subclass of: question on reaction after immunization
example of usage: Walgreens immunization informed consent: https://www.walgreens.com/images/pdfs/IN-2225/WAG_VAR_Form_EDIT_10172013_v1.pdf
creator: YL,YH
definition: a question textual entity that asks whether the questionee hasfainted or felt dizzy after a vaccination (i.e., immunization)

question on transfusion of blood products in past year
type: Class
subclass of: question on blood or blood product transfusion, or immune (gamma) globulin in past year
definition: a question textual entity that asks whether the questionee has been given transfusion of blood products in the past year

question on given immune (gamma) globulin in last year
type: Class
subclass of: question on blood or blood product transfusion, or immune (gamma) globulin in past year
creator: YL,YH
definition: a question textual entity that asks whether the questionee has been given immune (gamma) globulin in the past year

question on history of thymoma
type: Class
subclass of: question on thymus disease
subclass of: Restriction
  on property: is about
  some values from: thymoma
creator: YL,YH
definition: a question textual entity that asks whether the questionee has a history of thymoma

question on previous thymectomy procedure
type: Class
subclass of: question on thymus disease
creator: YL, YH
definition: a question textual entity that asks whether the questionee has his/her thymus removed previously

question on current antimalarial medication
type: Class
subclass of: question on current medication usage
creator: YL,YH
definition: a question textual entity that asks whether the questionee is currently under antimalarial medication
comment: asked in prior for using Oral thyphoid vaccine only

question on seizure, brain, or nerve problem
type: Class
subclass of: question on neurological disorder
definition: a question textual entity that asks whether the questionee has experienced any seizure disorder, brain or nerve problem.
term editor: YL, YH
has synonym: Have you had a seizure, brain, or other nervous system problem?
database_cross_reference: LOINC:66379-9

question on blood or blood product transfusion, or immune (gamma) globulin in past year
type: Class
subclass of: immunocompromisation question
example of usage: Cosco Pharmacy vaccine informed consent form: http://www2.costco.com/Images/Content/misc/PDF/Immunization_consent_form_v2-2012.pdf
has synonym: During the past year, have you received a transfusion of blood or blood products, including antibodies?
term editor: YL, YH
definition: a question textual entity that asks whether the questionee has conducted a blood or blood product transfusion, or given a medicine called immune (gamma) globulin, in the past year

question on woman pregnancy now or during the next month
type: Class
subclass of: question on woman pregnancy
subclass of: Restriction
  on property: asking vaccination patient
  some values from: female vaccination patient
term editor: YL, YH
database_cross_reference: LOINC:66381-5
definition: a question textual entity that asks whether a woman is pregnant now or could become pregrant during the next month

question on cancer, leukemia, AIDS or any other immune system problem
type: Class
subclass of: immunocompromisation question
example of usage: Cosco Pharmacy vaccine informed consent form: http://www2.costco.com/Images/Content/misc/PDF/Immunization_consent_form_v2-2012.pdf
term editor: YL, YH
definition: a question textual entity that asks whether the questionee has cancer, leukemia, AIDS or any other immune system problem

question whether currently sick with a moderate to high fever, vomiting/diarrhea
type: Class
subclass of: question whether currently sick
subclass of: Restriction
  on property: is about
  some values from: fever
subclass of: Restriction
  on property: is about
  some values from: sickness
subclass of: Restriction
  on property: is about
  some values from: diarrhea
term editor: YL, YH
definition: a question textual entity that asks whether the questionee is currently sick with a moderate to high fever, vomiting/diarrhea
example of usage: Walgreens immunization informed consent: https://www.walgreens.com/images/pdfs/IN-2225/WAG_VAR_Form_EDIT_10172013_v1.pdf

question on any medication affecting blood clotting
type: Class
subclass of: current treatment question
term editor: YL, YH
definition: a question textual entity that asks whether the questionee has taken any medication that affects blood clotting

question on history of thrombocytopenia or thrombocytopenic purpura
type: Class
subclass of: question on thymus disease
example of usage: Walgreens immunization informed consent: https://www.walgreens.com/images/pdfs/IN-2225/WAG_VAR_Form_EDIT_10172013_v1.pdf
creator: YL,YH
definition: a question textual entity that asks whether the questionee has a history of thrombocytopenia or thrombocytopenic purpura.

questionare for Manitoba Seasonal Influenza and Pneumococcal vaccination consent
type: Class
subclass of: questionnaire for Manitoba vaccination consent
subclass of: Restriction
  on property: has component
  some values from: question on reaction after immunization
subclass of: Restriction
  on property: has component
  some values from: allergy question
subclass of: Restriction
  on property: has component
  some values from: question on long-term health problem
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: Class
    union of: pneumococcal vaccination
    union of: influenza vaccination
subclass of: Restriction
  on property: has component
  some values from: question whether currently sick
definition: a questionnaire that is part of the vaccination informed consent form used for Seasonal Influenza and Phenumococcal vaccination in Manitoba, Canada.

question on long-term kidney disease
type: Class
subclass of: question on long-term health problem
subclass of: Restriction
  on property: is about
  some values from: kidney disease
definition: a question on long-term health problem that asks whether the questionee has a long-term kidney disease

question whether allergic to gentamicin
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to neomycin
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to formaldehyde
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to thimerosal
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to bovine protein
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to phenol
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to polymyxin
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to gelatin
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to yeast
type: Class
subclass of: question whether allergic to vaccine component

question whether allergic to baker’s yeast
type: Class
subclass of: question whether allergic to vaccine component

question on vaccination caused disorder
type: Class
subclass of: question on serious reaction after immunization

question on vaccination caused Guillain-Barre syndrome
type: Class
subclass of: question on vaccination caused disorder
subclass of: question on neurological disorder
subclass of: Restriction
  on property: is about
  some values from: Guillain-Barre syndrome
subclass of: Restriction
  on property: is about
  some values from: Guillain-Barre syndrome AE

question on neurological disorder
type: Class
subclass of: question on health condition requires doctor visit

question whether relate to new born infant
type: Class
subclass of: question whether live with immunocompromise person
has synonym: Are you a parent, family member, or caregiver to a new born infant?
creator: YL
definition: a question asks the questionee if he or she is taking care of a new born infant or close family member of a new born infant.

question on asthma history
type: Class
subclass of: question on asthma or wheezing history
subclass of: Restriction
  on property: is about
  some values from: asthma

question on wheezing history
type: Class
subclass of: question on asthma or wheezing history
subclass of: Restriction
  on property: is about
  some values from: wheezing

question on serious reaction after immunization
type: Class
subclass of: question on reaction after immunization
subclass of: Restriction
  on property: is about
  some values from: serious vaccine adverse event

question whether a parent of a new born infant
type: Class
subclass of: question whether a family member of a new born infant

question whether a family member of a new born infant
type: Class
subclass of: question whether relate to new born infant

question whether a care giver of a new born infant
type: Class
subclass of: question whether relate to new born infant

question whether smoke
type: Class
subclass of: current health condition question
has synonym: Do you smoke?

question on past vaccination information
type: Class
subclass of: previous medical precedure question
subclass of: Restriction
  on property: is about
  some values from: Class
    union of: vaccine adverse event
    union of: vaccination
term editor: YL
definition: questions that related to patient's vaccination history, warnings received from health provider about a certain vaccination, and adverse event related with a vaccination.

question whether had Pneumococcal vaccination
type: Class
subclass of: question on past vaccination information
subclass of: Restriction
  on property: is about
  some values from: pneumococcal vaccination

question whether had Shingles vaccination
type: Class
subclass of: question on past vaccination information
subclass of: Restriction
  on property: is about
  some values from: shingles vaccination

question whether had Tdap vaccination
type: Class
subclass of: question on past vaccination information
subclass of: Restriction
  on property: is about
  some values from: Tdap vaccination

question on antiviral drug usage
type: Class
subclass of: question on current antibiotics usage

question on whether having cut, injury, puncture or open wound
type: Class
subclass of: question on current condition leads to skin break
subclass of: Restriction
  on property: is about vaccination procedure
  some values from: Tdap vaccination
has synonym: Do you have a cut, injury, puncture or open wound that prompted you to get a tetanus shot?

question on COPD
type: Class
subclass of: question on long-term lung disease
subclass of: Restriction
  on property: is about
  some values from: chronic obstructive pulmonary disease

question whether react to triple antibiotic ointment
type: Class
subclass of: allergy question

question on health provider precaution or warning of specific vaccination
type: Class
subclass of: question on past vaccination information
example of usage: Has any physician or other healthcare professional ever cautioned or warned you about receiving certain vaccines or receiving vaccines outside of a medical setting? *
term editor: YL
definition: a question asks if the vaccination patient received warning or precaution information from his/her health provider in the past.

question about vaccination patient age
type: Class
subclass of: question textual entity

question on long-term liver disease
type: Class
subclass of: question on long-term health problem
subclass of: Restriction
  on property: is about
  some values from: liver disease

question on faintig after vaccination
type: Class
subclass of: question on whether fainted or felt dizzy after immunization
subclass of: Restriction
  on property: is about
  some values from: syncope AE
subclass of: Restriction
  on property: is about
  some values from: faint

question on long-term aspirin therapy
type: Class
subclass of: question on current aspirin medication

question whether patient is older than 18 years old
type: Class
subclass of: question about vaccination patient age
has_exact_synonym: Are you 18 years of age or older?

question on whether having atopic dermatitis
type: Class
subclass of: question on current condition leads to skin break

question whether diagnosed with rheumatoid arthritis
type: Class
subclass of: question on autoimmune disease
subclass of: Restriction
  on property: is about
  some values from: rheumatoid arthritis

question whether diagnosed with ankylosing spondylitis
type: Class
subclass of: question on autoimmune disease
subclass of: Restriction
  on property: is about
  some values from: ankylosing spondylitis

question whether diagnosed with Crohn’s disease
type: Class
subclass of: question on autoimmune disease
subclass of: Restriction
  on property: is about
  some values from: Crohn's disease

question whether diagnosed with Guillain-Barre syndrome
type: Class
subclass of: question on neurological disorder
subclass of: Restriction
  on property: is about
  some values from: Guillain-Barre syndrome
has_exact_synonym: Have you ever been diagnosed as having Guillain-Barre syndrome?

question on health condition requires doctor visit
type: Class
subclass of: current health condition question

question whether had chickenpox
type: Class
subclass of: previous medical precedure question
subclass of: Restriction
  on property: is about
  some values from: chickenpox
definition: a question textual entity that asks the patient whether he/she had diagnosed, treated and recovered from chickenpox, or varicella-zoster virus (VZV) infection.

question on dizzy after vaccination
type: Class
subclass of: question on whether fainted or felt dizzy after immunization
subclass of: Restriction
  on property: is about
  some values from: dizziness AE
subclass of: Restriction
  on property: is about
  some values from: dizziness

question whether bring imunization record card
type: Class
subclass of: question textual entity
example of usage: Did you bring your Immunization Record Card with you?

question on asplenia
type: Class
subclass of: immunocompromisation question
subclass of: Restriction
  on property: is about
  some values from: asplenia

question on CSF leak
type: Class
subclass of: current health condition question
subclass of: Restriction
  on property: is about
  some values from: cerebrospinal fluid leak

question on cochlear implant
type: Class
subclass of: previous medical precedure question
subclass of: Restriction
  on property: is about
  some values from: cochlear implant
creation date: 01/25/2016
comment: The United States Food and Drug Administration reports that cochlear implant recipients may be at higher risk for meningitis.[76] A study of 4,265 American children who received implants between 1997 and 2002 concluded that recipient children had a risk of pneumococcal meningitis more than 30 times greater than that for children in the general population.A later, UK-based, study found that while the incidence of meningitis in implanted adults was significantly higher than the general population, the incidence in children was no different from the general population. As a result, the Centers for Disease Control and Prevention and the Food and Drug Administration both recommend that would-be implant recipients be vaccinated against meningitis prior to surgery.(https://en.wikipedia.org/wiki/Cochlear_implant)
created by: YL

question on weekly injection
type: Class
subclass of: question on current medication usage

question on weekly injection of adalmumab
type: Class
subclass of: question on weekly injection

question on weekly injection of infliximab
type: Class
subclass of: question on weekly injection

question on weekly injection of etanercept
type: Class
subclass of: question on weekly injection

question on home infusion
type: Class
subclass of: current treatment question

question on high-dose methotrexate usage
type: Class
subclass of: current treatment question

question on azathioprine or 6-mercaptopurine usage
type: Class
subclass of: immunocompromisation question
subclass of: current treatment question

question on current anti-malarial medication
type: Class
subclass of: question on current antibiotics usage

question whether recieving aspirin-containing therapy
type: Class
subclass of: current treatment question

5 year and younger vaccination patient
type: Class
subclass of: minor vaccination patient
definition: a minor vaccination patient whose age is younger thatn 5 or equal to 5.

question on fever
type: Class
subclass of: question whether currently sick
subclass of: Restriction
  on property: is about
  some values from: fever
has synonym: Do you have a fever?

question whether allergic to egg products
type: Class
subclass of: question whether allergic to food
subclass of: Restriction
  on property: is about
  some values from: egg allergy

question on stroke leading brain or nerve damage
type: Class
subclass of: question on brain or nerve damage

question on convulsion leading brain or nerve damage
type: Class
subclass of: question on brain or nerve damage

question on brain or nerve damage
type: Class
subclass of: question on seizure, brain, or nerve problem

question on respiratory illness
type: Class
subclass of: question whether currently sick
subclass of: Restriction
  on property: is about
  some values from: respiratory system and chest symptom
creator: YL
definition: question that is about the patient's repiratory system or chest symptoms.

question whether in contact with severely immunocompromised person
type: Class
subclass of: immunocompromisation question

question on woman's possibility of geting pregnant
type: Class
subclass of: question on woman pregnancy
example of usage: Is there a possibility of pregnancy? <used in UM College Park injectable influenza vaccination consent questionnaire> [VICO_0000065]
comment: Pregnancy tests prior to vaccination are not routinely recommended. However, females of childbearing age should be asked about the possibility of their being pregnant prior to being given any vaccine for which pregnancy is a contraindication or precaution. The patient's answer should be documented in the medical record. If the patient is uncertain if she is pregnant, a test should be performed before administering live virus vaccines (measles-mumps-rubella, varicella, live attenuated influenza, yellow fever). (http://www.immunize.org/askexperts/precautions-contraindications.asp)

question on agammaglobulinemia
type: Class
subclass of: immunocompromisation question

question on lymphoma
type: Class
subclass of: question on cancer

question on severe autoimmune disease
type: Class
subclass of: immunocompromisation question

question on SLE
type: Class
subclass of: question on severe autoimmune disease

question on immunosuppressive drug usage
type: Class
subclass of: immunocompromisation question

question on drug usage after organ transplant
type: Class
subclass of: question on immunosuppressive drug usage

question on autoimmune disease drug usage
type: Class
subclass of: question on current medication usage

question on cancer treatment
type: Class
subclass of: current treatment question

question on autoimmune disease
type: Class
subclass of: question on health condition requires doctor visit

question on current condition leads to skin break
type: Class
subclass of: current health condition question

question onwhether having skin rash
type: Class
subclass of: question on current condition leads to skin break

question on whethere having severe burn
type: Class
subclass of: question on current condition leads to skin break

question on whether having impetigo
type: Class
subclass of: question on current condition leads to skin break

question whether having chickenpox
type: Class
subclass of: question on current condition leads to skin break

question on whether having shingles
type: Class
subclass of: question on current condition leads to skin break

question on whether having herpes
type: Class
subclass of: question on current condition leads to skin break

question on whether having psoriasis
type: Class
subclass of: question on current condition leads to skin break

question on whether having severe acne
type: Class
subclass of: question on current condition leads to skin break

question on Darier's disease
type: Class
subclass of: question on current condition leads to skin break

question on whether using steroid eye drop
type: Class
subclass of: steroids treatment question

question on whether diagnosed with myocardial infarction
type: Class
subclass of: question on health condition requires doctor visit

question on whether diagnosed with angina
type: Class
subclass of: question on health condition requires doctor visit

question on whether diagnosed with congestive heart failure
type: Class
subclass of: question on health condition requires doctor visit

question on whether diagnosed with cardiomyopathy
type: Class
subclass of: question on health condition requires doctor visit

question on whether had transient ischemic attack
type: Class
subclass of: question on seizure, brain, or nerve problem

question on chest pain
type: Class
subclass of: question on health condition requires doctor visit

question on shortness of breath when exert
type: Class
subclass of: question on health condition requires doctor visit

question whether allergic to smallpox vaccine
type: Class
subclass of: question whether allergic to vaccine

question whether allergic to polymixin B
type: Class
subclass of: question whether allergic to medication

question whether allergic to streptomycin
type: Class
subclass of: question whether allergic to medication

question whethere allergic to chlortetracycline
type: Class
subclass of: question whether allergic to medication

question whethere allergic to neomycin
type: Class
subclass of: question whether allergic to medication

question on last month's sexual intercourse without effecctive birth control
type: Class
subclass of: question on woman's possibility of geting pregnant

question on sexual intercourse without effecctive birth control after the vaccination
type: Class
subclass of: question on woman's possibility of geting pregnant

question whether live with a child less than one year old
type: Class
subclass of: question whether live with immunocompromise person

question whether current breast-feeding
type: Class
subclass of: question for woman

question for woman
type: Class
subclass of: question textual entity
subclass of: Restriction
  on property: asking vaccination patient
  all values from: female vaccination patient
comment: CDC guidance for pregnancy vaccination http://www.cdc.gov/vaccines/acip/committee/downloads/preg-principles-2008.pdf

question for household memeber of vaccination patient
type: Class
subclass of: question whether live with immunocompromise person

question for close physical contact person of vaccination patient
type: Class
subclass of: question whether live with immunocompromise person

question on current medication usage
type: Class
subclass of: current treatment question
term editor: YL
definition: question asks vaccination patient about current drug usage.

question whether had organ transplant
type: Class
subclass of: immunocompromisation question

question whether had chickenpox vaccination
type: Class
subclass of: question on past vaccination information

current health condition question
type: Class
subclass of: question textual entity
term editor: YL
definition: a question asks if the patient currently has any disease that requies regular doctor's vsisit, long tem disease that impacts current well-being, any symptoms, or feeling ill at the time when he/she is being accessed by vaccination providers.

previous medical precedure question
type: Class
subclass of: question textual entity

question whether live with immunocompromise person
type: Class
subclass of: immunocompromisation question

sickness
type: Class
subclass of: quality of a single physical entity
creation date: 01/17/2016
term editor: YL
definition: A disposition of ill health, bodily malfunction, or discomfort.
database_cross_reference: NCI:C107499
NC ithesaurus: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107499

immunocompromised condition
type: Class
subclass of: quality of a single physical entity
creation date: 01/17/2016
definition: A condition or state in which the immune system doesn't have ability to fight infectious disease or medical challenges.
comment: A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised person may be particularly vulnerable to opportunistic infections, in addition to normal infections that could affect everyone. Immunodeficiency may also decrease cancer immunosurveillance. Most cases of immunodeficiency are acquired ("secondary") but some people are born with defects in their immune system, or primary immunodeficiency. Transplant patients take medications to suppress their immune system as an anti-rejection measure, as do some patients suffering from an over-active immune system.
term editor: YL

functional asplenia
type: Class
subclass of: asplenia
definition: The organism's spleen doesn't work, or

anatomical asplenia
type: Class
subclass of: asplenia
definition: The organsim is lacking of the spleen as a part of its body.

asplenia
type: Class
subclass of: quality of a single physical entity
creation date: 01/17/2016
definition: Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks.
comment: Vaccinations It is suggested that splenectomized persons receive the following vaccinations, and ideally prior to planned splenectomy surgery: Pneumococcal polysaccharide vaccine (not before 2 years of age). Children may first need one or more boosters of pneumococcal conjugate vaccine if they did not complete the full childhood series. Haemophilus influenzae type b vaccine, especially if not received in childhood. For adults who have not been previously vaccinated, two doses given two months apart was advised in the new 2006 UK vaccination guidelines (in the UK may be given as a combined Hib/MenC vaccine). Meningococcal conjugate vaccine, especially if not received in adolescence. Previously vaccinated adults require a single booster and non-immunised adults advised, in UK since 2006, to have two doses given two months apart. Children too young for the conjugate vaccine should receive meningococcal polysaccharide vaccine in the interim. Influenza vaccine, every winter, to help prevent getting secondary bacterial infection. (https://en.wikipedia.org/wiki/Asplenia)
comment: Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks.Asplenia is a form of immunodeficiency, increasing the risk of sepsis from polysaccharide encapsulated bacteria,and can result in overwhelming post splenectomy infection (OPSI), often fatal within a few hours. In particular, patients are at risk from Streptococcus pneumoniae, Haemophilus influenzae, and meningococcus.The risk is elevated as much as 350–fold. (https://en.wikipedia.org/wiki/Asplenia)
created by: YL
term editor: YL

acquired immunocompromised condition due to transplant
type: Class
subclass of: sickness
creation date: 01/17/2016
definition: The immunocomproised condition accquired by transplant patients taking medications to suppress their immune system as an anti-rejection measure.
term editor: YL

cerebrospinal fluid leak
type: Class
subclass of: quality of a single physical entity
definition: A health condition where the fluid surrounding the brain and spinal cord escapes.
has_exact_synonym: CSF leak
term editor: YL
comment: http://www.adultvaccination.org/professional-resources/pneumo/adult-pneumo-guide-hcp.pdf

cochlear implant
type: Class
subclass of: process
comment: The United States Food and Drug Administration reports that cochlear implant recipients may be at higher risk for meningitis.[76] A study of 4,265 American children who received implants between 1997 and 2002 concluded that recipient children had a risk of pneumococcal meningitis more than 30 times greater than that for children in the general population.[77] A later, UK-based, study found that while the incidence of meningitis in implanted adults was significantly higher than the general population, the incidence in children was no different from the general population.[78] As a result, the Centers for Disease Control and Prevention and the Food and Drug Administration both recommend that would-be implant recipients be vaccinated against meningitis prior to surgery.[79]
term editor: YL
definition: a condition of person who has been surgically implanted an electronic device under the skin behind the ear to provide hearing.
comment: http://www.adultvaccination.org/professional-resources/pneumo/adult-pneumo-guide-hcp.pdf

serious vaccine adverse event
type: Class
equivalent class: Class
  intersection of: vaccine adverse event
  intersection of: serious adverse event
subclass of: adverse event

pregancy
type: Class
subclass of: process
database_cross_reference: http://www.ebi.ac.uk/efo/EFO_0002950
creation date: 01/25/2016
NC ithesaurus: NCI:C25742
term editor: YL
database_cross_reference: UMLS CUI:C0032961
definition source: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp
database_cross_reference: NCI:C25742
definition: The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth.

burns
type: Class
subclass of: quality of a single physical entity
definition: A burn is an injury to the skin or other organic tissue primarily caused by heat or due to radiation, radioactivity, electricity, friction or contact with chemicals. Skin injuries due to ultraviolet radiation, radioactivity, electricity or chemicals, as well as respiratory damage resulting from smoke inhalation, are also considered to be burns.
NC ithesaurus: NCI:C34441
database_cross_reference: NCI:C34441
definition source: WHO (http://www.who.int/violence_injury_prevention/other_injury/burns/en/)
term editor: YL

breastfeeding
type: Class
subclass of: process
definition: The feeding of babies and young children with milk from a woman's breast.
term editor: YL
definition source: https://en.wikipedia.org/wiki/Breastfeeding

smoking behaviour
type: Class
subclass of: process
database_cross_reference: UMLS CUI:C1519386
definition source: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp
creation date: 01/25/2016
definition: A person's current tobacco and nicotine consumption as well as his/her smoking history.
database_cross_reference: http://www.ebi.ac.uk/efo/EFO_0004318
database_cross_reference: NCI:C19796
NC ithesaurus: NCI:C19796
term editor: YL

unprotected sexual intercourse
type: Class
subclass of: process
definition source: NCI thesaurus
NC ithesaurus: NCI:C88146
definition: Sexual intercourse without the use of precautions to prevent conception or the transmission of sexually transmitted diseases.
term editor: YL

part of pathogen organism in vaccine
type: Class
subclass of: vaccine component
term editor: YH
definition: 'part of organism in vaccine' is a pathogen component in vaccine that contains only a part of the pathogen organism instead of the whole organism.
imported from: vo.owl

vaccine
type: Class
equivalent class: Class
  intersection of: processed material
  intersection of: Restriction
    on property: has function at some time
    some values from: Class
      intersection of: vaccine function
      intersection of: Restriction
        on property: realized in
        some values from: vaccine immunization
  intersection of: Restriction
    on property: is_specified_output_of
    some values from: vaccine preparation
subclass of: processed material
editor note: Many vaccines are developed to protect against infectious pathogens. Many vaccines are also being developed against some diseases such as cancer and autoimmune diseases. Vaccine is developed against a disease. Allergy.
term editor: YH, BP, BS, MC, LC, XZ, RS
see also: MeSH: D014612
term editor: a role that inheres in a prepared material entity that is designed to induce protection or treament for a diease or infection in vivo.
definition: A vaccine is a processed material with the function that when administered, it prevents or ameliorates a disorder in a target organism by inducing or modifying adaptive immune responses specific to the antigens in the vaccine.
imported from: vo.owl

vaccination
type: Class
subclass of: planned process
subclass of: Restriction
  on property: has participant
  some values from: Class
    intersection of: organism
    intersection of: Restriction
      on property: has role at some time
      some values from: vaccine host role
subclass of: Restriction
  on property: has participant at all times
  some values from: vaccine
definition: a process of administering substance in vivo that involves in adding a vaccine into a host (e.g., human) in vivo with the intent to invoke a protective or therapeutic adaptive immune response.
alternative term: vaccine administration
term editor: YH, BP
imported from: vo.owl

ACAM2000
type: Class
subclass of: vaccinia virus vaccine
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_manufactured_by
  has value: Acambis, Inc
subclass of: Restriction
  on property: is_specified_input_of
  some values from: percutaneous vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Smallpox (Vaccinia) Vaccine, Live
term editor: YH
see also: CVX: 75
comment: Trade Name: ACAM2000
imported from: vo.owl

ActHIB
type: Class
subclass of: Haemophilus influenzae serotype b vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, SA
subclass of: Restriction
  on property: has part
  some values from: capsular polysaccharide of pathogen organism as vaccine component
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
comment: Product Name: Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)
term editor: YH
see also: PMID: 1735812
see also: PMID: 1517908
comment: Trade Name: ActHIB
see also: CVX: 48
imported from: vo.owl

Adacel
type: Class
subclass of: Diphtheria-Tetanus-Pertussis vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
comment: Product Name: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed
see also: CVX: 20
comment: Trade Name: Adacel
see also: CVX: 115
term editor: YH
imported from: vo.owl

Afluria
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: CSL Limited
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has vaccine contraindication
  some values from: hypersensitivity to chicken egg
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_distributed_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
comment: Product Name: Influenza Virus Vaccine
see also: CVX: 141
comment: Trade Name: Afluria
see also: CVX: 140
definition source: WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
term editor: YH
imported from: vo.owl

Attenuvax
type: Class
subclass of: Measles virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Measles Virus Vaccine, Live
comment: Trade Name: Attenuvax
term editor: YH
imported from: vo.owl

Bacillus anthracis vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Bacillus anthracis
term editor: YH
definition: A vaccine that protects against Bacillus anthrax that causes anthrax.
alternative term: anthrax vaccine
see also: MeSH: D022122
imported from: vo.owl

Biothrax
type: Class
subclass of: Bacillus anthracis vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: BioPort Corp
subclass of: Restriction
  on property: has part
  some values from: protein of pathogen organism as vaccine component
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Anthrax Vaccine Adsorbed
term editor: YH
see also: CVX: 24
comment: Trade Name: Biothrax
imported from: vo.owl

Boostrix
type: Class
subclass of: Diphtheria-Tetanus-Pertussis vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
comment: Product Name: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed
see also: CVX: 115
term editor: YH
see also: CVX: 20
comment: Trade Name: Boostrix
imported from: vo.owl

Comvax
type: Class
subclass of: Haemophilus b and Hepatitis B vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
comment: Product Name: Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) & Hepatitis B Vaccine (Recombinant)
comment: Trade Name: Comvax
term editor: YH
see also: CVX: 51
imported from: vo.owl

Daptacel
type: Class
subclass of: Diphtheria-Tetanus-Pertussis vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed
term editor: YH
comment: Trade Name: DAPTACEL
see also: CVX: 106
editor note: Vaccine components see http://www.vaccinesafety.edu/components-DTaP.htm
see also: CVX: 20
imported from: vo.owl

DECAVAC
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Tetanus & Diphtheria Toxoids Adsorbed for Adult Use
term editor: YH
comment: Trade Name: DECAVAC
see also: CVX: 113
imported from: vo.owl

Diphtheria and Tetanus Toxoids Adsorbed USP by Sanofi Pasteur Inc
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
comment: Product Name: Diphtheria & Tetanus Toxoids Adsorbed
term editor: YH
see also: CVX: 28
imported from: vo.owl

Diphtheria and Tetanus Toxoids Adsorbed by Sanofi Pasteur Ltd
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Diphtheria & Tetanus Toxoids Adsorbed
term editor: YH
imported from: vo.owl

Dryvax
type: Class
subclass of: vaccinia virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Wyeth Pharmaceuticals Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Smallpox Vaccine, Dried, Calf Lymph Type
editor note: Dryvax is a freeze-dried calf lymph smallpox vaccine. It is the world's oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. By the 1940s, Wyeth was the leading US manufacturer of the vaccine and the only manufacturer by the 1960s. After world health authorities declared smallpox had been eradicated from nature in 1980, Wyeth stopped making the vaccine.
comment: Trade Name: Dryvax
term editor: YH
see also: CVX: 75
definition source: http://en.wikipedia.org/wiki/Dryvax
definition: a vaccinia virus vaccine that is a freeze-dried calf lymph smallpox vaccine, specifically, Dryvax is a live-virus preparation of vaccinia prepared from calf lymph.
imported from: vo.owl

FluLaval
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: ID Biomedical Corp of Quebec
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
comment: Product Name: Influenza Virus Vaccine, Trivalent, Types A and B
term editor: YH
comment: Trade Name: FluLaval
see also: CVX: 141
imported from: vo.owl

FluMist
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccinated in route
  some values from: intranasal route by spray
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Influenzavirus B
subclass of: Restriction
  on property: has quality at some time
  some values from: viral vaccine organism live attenuated
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: is_manufactured_by
  has value: MedImmune Vaccines, Inc
comment: Product Name: Influenza Virus Vaccine, Live, Intranasal
see also: CVX: 111
term editor: YH
definition source: WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
comment: Trade Name: FluMist
imported from: vo.owl

Fluarix
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Influenza Virus Vaccine, Trivalent, Types A and B
comment: Trade Name: Fluarix
term editor: YH
see also: CVX: 140
imported from: vo.owl

Fluvirin
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Novartis Vaccines and Diagnostics
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Influenza Virus Vaccine, Trivalent, Types A and B
comment: Trade Name: Fluvirin
see also: CVX: 140
see also: CVX: 141
term editor: YH
imported from: vo.owl

Fluzone
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
comment: Product Name: Influenza Virus Vaccine, Trivalent, Types A and B
see also: CVX: 141
term editor: YH
see also: CVX: 140
see also: CVX: 144
comment: Trade Name: Fluzone
imported from: vo.owl

Gardasil
type: Class
subclass of: human papillomavirus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: has part
  some values from: protein of pathogen organism as vaccine component
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
see also: CVX: 62
comment: Trade Name: Gardasil
term editor: YH
imported from: vo.owl

Havrix
type: Class
subclass of: Hepatitis A virus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
comment: Product Name: Hepatitis A Vaccine, Inactivated
comment: Trade Name: Havrix
term editor: YH
see also: CVX: 83
see also: CVX: 52
imported from: vo.owl

Neisseria meningitidis vaccine
type: Class
equivalent class: Class
  intersection of: bacterial vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Neisseria meningitidis
subclass of: bacterial vaccine
definition: A bacterial vaccine that prevents Neisseria meningitidis infection.
alternative term: Meningococcal vaccine
see also: MeSH: D022401
term editor: YH
imported from: vo.owl

IPOL
type: Class
subclass of: Poliovirus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, SA
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: subcutaneous vaccination
comment: Product Name: Poliovirus Vaccine Inactivated (Monkey Kidney Cell)
term editor: YH
comment: Trade Name: IPOL
see also: CVX: 10
imported from: vo.owl

Imovax Rabies (USA)
type: Class
subclass of: Rabies virus vaccine
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, SA
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Rabies Vaccine
term editor: YH
see also: CVX: 18
comment: Trade Name: Imovax
imported from: vo.owl

Infanrix
type: Class
subclass of: Diphtheria-Tetanus-Pertussis vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has part
  some values from: protein of pathogen organism as vaccine component
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
comment: Product Name: Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed
term editor: YH
see also: CVX: 20
comment: Trade Name: Infanrix
imported from: vo.owl

Influenza Virus Vaccine H5N1 (Sanofi Pasteur Inc)
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: H5N1 subtype
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Influenza Virus Vaccine, H5N1 (for National Stockpile)
term editor: YH
definition source: WEB: http://atomicnewsreview.org/2009/10/22/approval-for-the-arepanrix%E2%84%A2-gsk-vaccine-in-canada/
imported from: vo.owl

JE-Vax
type: Class
subclass of: Japanese encephalitis virus vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: subcutaneous vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Research Foundation for Microbial Diseases of Osaka University
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Japanese Encephalitis Virus Vaccine Inactivated
term editor: YH
see also: CVX: 39
comment: Trade Name: JE-Vax
imported from: vo.owl

Kinrix
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: protein of pathogen organism as vaccine component
comment: Product Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine
comment: Trade Name: KINRIX
see also: CVX: 130
term editor: YH
imported from: vo.owl

M-M-R II
type: Class
subclass of: Measles-Mumps-Rubella vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: has quality at some time
  some values from: viral vaccine organism live attenuated
comment: Product Name: Measles, Mumps, and Rubella Virus Vaccine, Live
comment: Trade Name: M-M-R II
term editor: YH
definition: A Measles-Mumps-Rubella vaccine that is live attenuated and manufactured by Merck & Co, Inc.
see also: CVX: 03
imported from: vo.owl

M-M-Vax
type: Class
subclass of: Measles-Mumps vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
comment: Product Name: Measles and Mumps Virus Vaccine, Live
definition: A Measles-Mumps vaccine that is manufactured by Merck and used for human.
term editor: YH
comment: Trade Name: M-M-Vax
imported from: vo.owl

Menactra
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine
term editor: YH
definition source: WEB: http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm176044.htm
comment: Trade Name: Menactra
alternative term: Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine
see also: CVX: 114
imported from: vo.owl

Menomune A C Y W135
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Meningococcal Polysaccharide Vaccine, Groups A, C, Y and W-135 Combined
term editor: YH
comment: Trade Name: Menomune-A/C/Y/W-135
see also: CVX: 32
imported from: vo.owl

Meruvax II
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: subcutaneous vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Rubella Virus Vaccine Live
see also: CVX: 06
comment: Trade Name: Meruvax II
term editor: YH
imported from: vo.owl

Mumpsvax
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
comment: Product Name: Mumps Virus Vaccine Live
comment: Trade Name: Mumpsvax
term editor: YH
see also: CVX: 07
imported from: vo.owl

Mycobax
type: Class
subclass of: BCG vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: BCG Vaccine
comment: Trade Name: Mycobax
term editor: YH
see also: CVX: 19
imported from: vo.owl

Fluzone High-dose
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Influenza Virus Vaccine, Trivalent, Types A and B
definition: an influenza vaccine that is similar to Fluzone but has high dose.
term editor: YH
definition source: WEB: http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM305079.pdf
see also: CVX: 140
see also: CVX: 141
comment: Trade Name: Fluzone
see also: CVX: 144
imported from: vo.owl

Influenza A (H1N1) 2009 Monovalent Vaccine (Novartis)
type: Class
subclass of: H1N1 Influenza vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Novartis Vaccines and Diagnostics
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
imported from: vo.owl

Pediarix
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: protein of pathogen organism as vaccine component
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
comment: Product Name: Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed, Hepatitis B (recombinant) and Inactivated Poliovirus Vaccine Combined
see also: CVX: 110
comment: Trade Name: Pediarix
term editor: YH
imported from: vo.owl

PedvaxHIB
type: Class
subclass of: Haemophilus influenzae serotype b vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
comment: Product Name: Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate)
see also: CVX: 49
term editor: YH
comment: Trade Name: PedvaxHIB
see also: PMID: 2791073
imported from: vo.owl

Pentacel
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has part
  some values from: protein of pathogen organism as vaccine component
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
comment: Product Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine
term editor: YH
see also: CVX: 120
comment: Trade Name: Pentacel
imported from: vo.owl

Plague Vaccine by Greer Laboratories Inc
type: Class
subclass of: Yersinia pestis vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Greer Laboratories Inc
comment: Product Name: Plague Vaccine
see also: CVX: 23
term editor: YH
imported from: vo.owl

Pneumovax 23 (USA)
type: Class
subclass of: polyvalent pneumococcal vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: has part
  some values from: phenol vaccine preservative
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Pneumococcal Vaccine, Polyvalent
see also: CVX: 33
comment: Trade Name: Pneumovax 23
term editor: YH
imported from: vo.owl

Poliovax
type: Class
subclass of: Poliovirus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
comment: Product Name: Poliovirus Vaccine Inactivated (Human Diploid Cell)
comment: Trade Name: Poliovax
term editor: YH
imported from: vo.owl

Prevnar (USA)
type: Class
subclass of: polyvalent pneumococcal vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: Wyeth Pharmaceuticals Inc
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
comment: Product Name: Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein)
term editor: YH
comment: Trade Name: Prevnar
see also: CVX: 100
imported from: vo.owl

ProQuad
type: Class
subclass of: Measles-Mumps-Rubella-Vericella vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
comment: Product Name: Measles, Mumps, Rubella and Varicella Virus Vaccine Live
term editor: YH
definition: A Measles-Mumps-Rubella-Vericella vaccine that is live and manufactured by Merck & Co, Inc.
comment: Trade Name: ProQuad
definition source: WEB: http://www.merck.com/product/usa/pi_circulars/p/proquad/proquad_pi.pdf
see also: CVX: 94
imported from: vo.owl

Fluzone intradermal
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intradermal vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
comment: Trade Name: Fluzone intradermal
definition source: WEB: http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM305080.pdf
term editor: YH
imported from: vo.owl

RabAvert
type: Class
subclass of: Rabies virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Novartis Vaccines and Diagnostics
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: chicken ovalbumin egg protein allergen
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Rabies Vaccine
definition source: WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
see also: CVX: 18
comment: Trade Name: RabAvert
term editor: YH
imported from: vo.owl

Rabies Vaccine Adsorbed by BioPort Corp
type: Class
subclass of: Rabies virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: BioPort Corp
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Rabies Vaccine Adsorbed
term editor: YH
imported from: vo.owl

RotaTeq
type: Class
subclass of: Rotavirus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: oral vaccination
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
comment: Product Name: Rotavirus Vaccine, Live, Oral, Pentavalent
comment: Trade Name: RotaTeq
term editor: YH
see also: CVX: 116
imported from: vo.owl

TENIVAC
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
comment: Product Name: Tetanus & Diphtheria Toxoids Adsorbed for Adult Use
term editor: YH
comment: Trade Name: TENIVAC
imported from: vo.owl

TICE BCG
type: Class
subclass of: cancer vaccine
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Organon Teknika Corp LLC
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intravesical vaccination
editor note: Intravesical TICE BCG has been used as a therapy for, and to prevent recurrence of, tumors in patients with carcinoma in situ (CIS) of the urinary bladder, and to prevent recurrence of Stage Ta T1 papillary tumors of the bladder at high risk of recurrence. Refernce URL: http://www.ticebcg.com/Consumer/aboutTice/index.asp
comment: Product Name: BCG Vaccine
see also: CVX: 19
comment: Trade Name: TICE BCG
term editor: YH
imported from: vo.owl

TYPHIM Vi
type: Class
subclass of: Salmonella typhi vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, SA
comment: Product Name: Typhoid Vi Polysaccharide Vaccine
see also: CVX: 101
comment: Trade Name: TYPHIM Vi
term editor: YH
imported from: vo.owl

Tetanus Toxoid Adsorbed by Aventis Pasteur Inc
type: Class
subclass of: Clostridium tetani vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
subclass of: Restriction
  on property: has part
  some values from: thimerosal vaccine preservative
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
comment: Product Name: Tetanus Toxoid Adsorbed
term editor: YH
see also: CVX: 35
imported from: vo.owl

Tetanus and Diphtheria Toxoids Adsorbed by MA Biologic Lab
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Massachusetts Public Health Biologic Lab
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Tetanus & Diphtheria Toxoids Adsorbed for Adult Use
term editor: YH
imported from: vo.owl

Tripedia
type: Class
subclass of: Diphtheria-Tetanus-Pertussis vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
comment: Product Name: Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed
comment: Trade Name: Tripedia
see also: CVX: 20
term editor: YH
imported from: vo.owl

Twinrix
type: Class
subclass of: Hepatitis A&B vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
comment: Product Name: Hepatitis A Inactivated and Hepatitis B (Recombinant) Vaccine
see also: CVX: 104
term editor: YH
comment: Trade Name: Twinrix
imported from: vo.owl

Varivax
type: Class
subclass of: Varicella-zoster virus live vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_specified_input_of
  some values from: subcutaneous vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Varicella Virus Vaccine Live
comment: Trade Name: Varivax
term editor: YH
see also: CVX: 21
imported from: vo.owl

Vivotif (USA)
type: Class
subclass of: Salmonella typhi vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Berna Biotech, Ltd
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
comment: Product Name: Typhoid Vaccine Live Oral Ty21a
see also: CVX: 25
comment: Trade Name: Vivotif
term editor: YH
imported from: vo.owl

YF-Vax
type: Class
subclass of: Yellow fever virus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_specified_input_of
  some values from: subcutaneous vaccination
comment: Product Name: Yellow Fever Vaccine
comment: Trade Name: YF-Vax
term editor: YH
definition source: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
see also: CVX: 37
imported from: vo.owl

Yellow fever virus vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Yellow fever virus
definition: A viral vaccine that protects against infection with Yellow fever virus.
see also: MeSH: D022341
term editor: YH
imported from: vo.owl

Zostavax
type: Class
subclass of: Varicella-zoster virus live vaccine
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: subcutaneous vaccination
comment: Product Name: Zoster Vaccine, Live, (Oka/Merck)
see also: CVX: 121
term editor: YH
comment: Trade Name: Zostavax
imported from: vo.owl

vaccine adjuvant role
type: Class
subclass of: vaccine additive role
definition: an adjuvant role that inheres in a vaccine component which is added as part of a vaccine and induces enhanced adaptive immune response to the vaccine antigen.
term editor: YH
imported from: vo.owl

Influenza A (H1N1) 2009 Monovalent Vaccine (Sanofi Pasteur)
type: Class
subclass of: H1N1 Influenza vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
imported from: vo.owl

bacterial vaccine
type: Class
equivalent class: Class
  intersection of: vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Bacteria
definition: A vaccine that targets against a bacterial disease.
see also: MeSH: D001428
term editor: YH
imported from: vo.owl

vaccine organism live attenuated
type: Class
subclass of: quality of a single physical entity
definition: a virulence of vaccine organism that shows an attenuated pheontype of the organism as the major component of a vaccine.
term editor: YH
imported from: vo.owl

cancer vaccine
type: Class
subclass of: vaccine
subclass of: Restriction
  on property: vaccine immunization against disase
  some values from: cancer
alternative term: neoplasm vaccine
see also: MeSH: D019496
term editor: YH
definition: A vaccine that prevents or treats cancer. It is produced using the patient's own whole tumor cells as the source of antigens, or using tumor-specific antigens, often recombinantly produced.
alternative term: tumor vaccine
imported from: vo.owl

vaccine component
type: Class
equivalent class: Class
  intersection of: material entity
  intersection of: Restriction
    on property: part of
    some values from: vaccine
term editor: YH
definition: a processed material that is output of the vaccine preparation and part of a vaccine.
alternative term: vaccine ingredient
alternative term: cardinal part of vaccine
imported from: vo.owl

vaccine organism inactivated
type: Class
subclass of: quality of a single physical entity
definition: an organismal quality of a whole organism vaccine where the whole organism is inactivated/killed and lacks the capability of replication.
alternative term: vaccine organism killed
term editor: YH
imported from: vo.owl

hypersensitivity to chicken egg
type: Class
subclass of: disposition
term editor: YH
imported from: vo.owl

vaccine function
type: Class
equivalent class: Class
  union of: preventive vaccine function
  union of: therapeutic vaccine function
subclass of: disposition
term editor: YH, MC, XZ, and AR
editor note: PERSPN: Oliver He: There has been hot discussion about whether we use 'vaccine function' or 'vaccine role'. Vaccine role may not be the good term to use. Vaccine is designed to be 'vaccine', so it should be vaccine function. One special case is cowpox virus. The cowpox virus can be mixed with some liquid like water and used as a smallpox vaccine. In this case, people often say: the cowpox virus has a 'vaccine role'. However, the cowpox virus vaccine is a processed material of a mix of the virus with water. The virus is a virus, it is not a vaccine per se. Therefore, vaccine role may not be an accurate term.
definition: vaccine function is a function that inheres in a vaccine that induces protective immune response against a disease. It is realized in the immunization process in the host.
imported from: vo.owl

company
type: Class
subclass of: organization
term editor: YH
imported from: vo.owl

intramuscular route
type: Class
subclass of: route of administration
subclass of: Restriction
  on property: located in at some time
  some values from: skeletal muscle tissue
definition: a route of administration that inject the material(such as vaccines, allergens) directly into a muscle.
has synonym: I.M.
term editor: YH,YL
alternative term: intramuscular injection route
imported from: vo.owl

intranasal route
type: Class
subclass of: route of administration
subclass of: Restriction
  on property: located in at all times
  some values from: nose structure
term editor: YH
definition: rounte of administration that located in nose.
has synonym: I.N.
imported from: vo.owl

intranasal route by spray
type: Class
subclass of: intranasal route
term editor: YH
imported from: vo.owl

Influenza A (H1N1) 2009 Monovalent Vaccine (CSL Limited)
type: Class
subclass of: H1N1 Influenza vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: CSL Limited
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
imported from: vo.owl

vaccine additive role
type: Class
subclass of: vaccine component role
definition source: Page 73, Chapter 6, Vaccine, 5th Edition. EXPERT CONSULT by Plotkin SA., et. al. 2008
definition source: a role inheres in a material entity, that has been added into a vaccine's formulation by the manufacture for a specific purpose. For example: adjuvant to enhance the effect of immunogen, perservatives, stablizers and those materials added for affecting PH and isotonicity.
term editor: YL,YH
imported from: vo.owl

Menactra injection 0.5mL vial
type: Class
subclass of: Menactra
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
comment: Product Name: Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine injection 0.5mL vial
term editor: YH
alternative term: Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine injection 0.5mL vial
definition source: WEB: http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm176044.htm
see also: SNOMEDCT: 416532007; UMLS_CUI:C1563043
comment: Trade Name: Menactra
imported from: vo.owl

Varicella-zoster virus live vaccine
type: Class
subclass of: Varicella-zoster virus vaccine
see also: SNOMEDCT: 412530002; ULMS_CUI: C0770687
definition: a Varicella-zoster virus vaccine that is live attenuated.
term editor: YH
imported from: vo.owl

polyvalent pneumococcal vaccine
type: Class
subclass of: Streptococcus pneumoniae vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: phenol vaccine preservative
subclass of: Restriction
  on property: has part
  some values from: capsular polysaccharide of pathogen organism as vaccine component
term editor: YH
definition source: WEB: http://www.who.int/vaccines/en/pneumococcus.shtml
definition: a pneumococcal vaccine that is formed using polyvalent polysaccharides
comment: The most common form of the polyvalent pneumococcal vaccine is called the protein-polysaccharide combinations which is known as conjugate vaccines and contain 7–11 selected polysaccharides bound to a protein carrier. The protein-polysaccharide combinations are able to induce a T-cell dependent immune response. These vaccines are likely to be protective even in children under two years of age, and may reduce pneumococcal transmission through a herd effect.
imported from: vo.owl

vaccinia virus vaccine
type: Class
subclass of: Smallpox virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at some time
  some values from: viral vaccine organism live attenuated
subclass of: Restriction
  on property: is_specified_input_of
  some values from: percutaneous vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: Acambis, Inc
definition source: WEB: http://en.wikipedia.org/wiki/Vaccinia
definition: a Smallpox virus vaccine that uses vaccinia virus
term editor: YH
comment: Vaccinia virus is well known for its role as a vaccine that helped eradicate the smallpox disease, making it the first human disease to be successfully eradicated by science.
imported from: vo.owl

preventive vaccine function
type: Class
subclass of: vaccine function
subclass of: Restriction
  on property: realized in
  some values from: disorder prevention
subclass of: Restriction
  on property: realized in
  some values from: induction of adaptive immune response to antigen
subclass of: Restriction
  on property: realized in
  some values from: vaccination
definition: preventive vaccine function is a vaccine function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which protects against a specific disorder.
alternative term: prophylactic vaccine function
term editor: YH
imported from: vo.owl

protein of pathogen organism as vaccine component
type: Class
subclass of: part of pathogen organism in vaccine
term editor: YH
imported from: vo.owl

chicken ovalbumin egg protein allergen
type: Class
subclass of: vaccine allergen
definition source: WEB: http://en.wikipedia.org/wiki/Ovalbumin
term editor: a chicken egg protein allergen where the protein allergen is ovalbumin, the main protein found in egg write, making up 60-65% of the total protein.
term editor: YH
imported from: vo.owl

typhoid live oral vaccine
type: Class
subclass of: Salmonella typhi vaccine
term editor: YH
term editor: a S. typhi vaccine that is live and orally administerred
see also: UMLS_CUI: C0359940; SNOMEDCT: 346696005
imported from: vo.owl

active immunization
type: Class
subclass of: process
term editor: YH, XZ
definition source: WEB: http://en.wikipedia.org/wiki/Immunization
definition: Active immunization is an immunization process that entails the introduction of a foreign molecule into the body, which causes the body itself to generate adaptive immunity against the target.
imported from: vo.owl

vaccine immunization
type: Class
subclass of: active immunization
subclass of: Restriction
  on property: has_specified_input
  some values from: vaccine
subclass of: Restriction
  on property: achieves_planned_objective
  some values from: immunization objective
subclass of: Restriction
  on property: realizes
  some values from: Class
    intersection of: vaccine host role
    intersection of: Restriction
      on property: inheres_in
      some values from: organism
definition: artificial active immunization is an active immunization that occurs when a person or animal is vaccinated with a specific vaccine.
alternative term: artificial active immunization
definition source: WEB: http://en.wikipedia.org/wiki/Immunization
term editor: YH, XZ
imported from: vo.owl

induction of adaptive immune response to antigen
type: Class
subclass of: active immunization
term editor: YH, XZ
definition: induction of adaptive immune response to antigen is an active immunization process that results in induction of adaptive immune response to some antigens, for example, in a vaccine.
imported from: vo.owl

disorder prevention
type: Class
subclass of: process
definition: disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease.
term editor: YH, XZ
imported from: vo.owl

disorder treatment
type: Class
subclass of: process
definition: disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease.
term editor: YH, XZ
imported from: vo.owl

modification of adaptive immune response to antigen
type: Class
subclass of: active immunization
definition: modification of adaptive immune response to antigen is an active immunization process that results in modification of an adaptive immune response to some antigens, for example, in a therapeutic vaccine.
term editor: YH, XZ
imported from: vo.owl

subcutaneous route
type: Class
subclass of: route of administration
subclass of: Restriction
  on property: located in at some time
  some values from: hypodermis
creator: YH
term editor: YL
has synonym: S.C.
definition: a route of administration that is loacted in the hypodermis (subcutaneous tissue) region.
imported from: vo.owl

human vaccinee
type: Class
subclass of: Homo sapiens
subclass of: Restriction
  on property: has role at all times
  some values from: vaccine host role
subclass of: Restriction
  on property: part of
  some values from: human vaccinee
definition: a human who has been administrated a vaccine
definition: a vaccinee that is a human being
imported from: vo.owl

therapeutic vaccine function
type: Class
subclass of: vaccine function
subclass of: Class
  union of: Restriction
    on property: realized in
    some values from: induction of adaptive immune response to antigen
  union of: Restriction
    on property: realized in
    some values from: modification of adaptive immune response to antigen
subclass of: Restriction
  on property: realized in
  some values from: disorder treatment
subclass of: Restriction
  on property: realized in
  some values from: vaccination
term editor: YH
definition: The therapeutic vaccine function is a function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which ameliorates a specific disorder.
imported from: vo.owl

route of administration
type: Class
subclass of: immaterial entity
subclass of: Restriction
  on property: located in at all times
  some values from: gross anatomical part
term editor: YH,YL
editor note: CDISC has a codelist: Rout of Administration. Desription from CDISC: The course by which a substance was administered in order to reach the site of action in the body. CDISC_SDTM_Route_of_Administration_Terminology
definition source: http://en.wikipedia.org/wiki/Route_of_administration
definition: a path that is located in gross anatomical part of an organism (e.g., human) and is used for administering a vaccine, a drug, fluid, poison, or other substance into the body.
imported from: vo.owl

thimerosal vaccine preservative
type: Class
subclass of: vaccine preservative
subclass of: Restriction
  on property: has part
  some values from: thimerosal
definition: vaccine preservative that has thimerosal as part.
term editor: YH
imported from: vo.owl

H1N1 Influenza vaccine
type: Class
equivalent class: Class
  intersection of: Influenza virus vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: H1N1 subtype
subclass of: Influenza virus vaccine
definition: H1N1 Influenza vaccine is an Influenza virus vaccine that is used to vaccinate against H1N1 Influenza subtype vaccine.
term editor: YH
imported from: vo.owl

vaccine adjuvant
type: Class
equivalent class: Class
  intersection of: vaccine component
  intersection of: Restriction
    on property: has role at some time
    some values from: vaccine adjuvant role
definition: a vaccine component that is chemical substance added to vaccine and enhance and direct immune response to protective antigen. Many of vaccine adjuvants cause a range of serious side-effects.
term editor: YH
imported from: vo.owl

immunization objective
type: Class
subclass of: objective specification
definition source: WEB: http://en.wikipedia.org/wiki/Immunization
term editor: YH, XZ
definition: immunization objective is the specification of an objective to achieve immunization.
imported from: vo.owl

vaccine preparation
type: Class
subclass of: planned process
subclass of: Restriction
  on property: realizes
  some values from: Restriction
    on property: concretizes at some time
    some values from: vaccine target specification
subclass of: Restriction
  on property: has_specified_output
  some values from: vaccine
alternative term: vaccine production
alternative term: vaccine generation
definition: vaccine preparation is a manufacturing process to produce a vaccine.
term editor: YH, BP
imported from: vo.owl

viral vaccine
type: Class
equivalent class: Class
  intersection of: vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Viruses
definition: A vaccine that targets against a viral disease.
see also: MeSH: D014765
term editor: YH
imported from: vo.owl

vaccine role
type: Class
subclass of: role
term editor: YH
term editor: a role that inheres in a prepared material entity that is designed to induce protection or treatment for a disease or infection.
imported from: vo.owl

vaccine component role
type: Class
subclass of: role
subclass of: Restriction
  on property: inheres in at all times
  some values from: Restriction
    on property: part of
    some values from: vaccine
term editor: a role that inheres in a material entity that becomes an ingredient of a vaccine.
term editor: YH
imported from: vo.owl

conjugate vaccine role
type: Class
subclass of: vaccine role
definition: a vaccine role that indicates the vaccine being a conjugate vaccine.
term editor: YH
imported from: vo.owl

licensed vaccine role
type: Class
subclass of: vaccine role
term editor: YH
definition: licensed vaccine role is a regulation-assigned role that indicates that a vaccine obtains official approval for commercial production and selling on the market.
imported from: vo.owl

Clostridium vaccine
type: Class
subclass of: bacterial vaccine
term editor: YH
definition: A bacterial vaccine that protects against infection with Clostridium spp.
imported from: vo.owl

Clostridium tetani vaccine
type: Class
equivalent class: Class
  intersection of: Clostridium vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Clostridium tetani
alternative term: tetanus vaccine
term editor: YH
definition: a Clostridium vaccine that protects against infection with Clostridium tetani that causes tenanus.
imported from: vo.owl

Influenza virus vaccine
type: Class
subclass of: viral vaccine
see also: MeSH: D007252; UMLS_CUI: C0021403; SNOMEDCT: 46233009
definition: A viral vaccine that protects against infection with influenza virus.
term editor: YH
alternative term: Influenza vaccine
imported from: vo.owl

Hepatitis B virus vaccine
type: Class
equivalent class: Class
  intersection of: viral vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Hepatitis B virus
subclass of: viral vaccine
see also: MeSH: D017325
definition: A viral vaccine that protects against infection with Hepatitis B virus.
term editor: YH
imported from: vo.owl

Hepatitis A virus vaccine
type: Class
equivalent class: Class
  intersection of: viral vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Hepatitis A virus
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Hepatitis A virus
term editor: YH
see also: MeSH: D022362
definition: A viral vaccine that protects against infection with Hepatitis A virus.
imported from: vo.owl

Yersinia pestis vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Yersinia pestis
term editor: YH
definition: A bacteria vaccine that prevents against Yersinia pestis infection that causes plague.
alternative term: Plague vaccine
see also: MeSH: D010931; SNOMEDCT: 11866009; UMLS_CUI:C0032066
imported from: vo.owl

Rabies virus vaccine
type: Class
equivalent class: Class
  intersection of: viral vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Rabies virus
subclass of: viral vaccine
term editor: YH
see also: MeSH: D011819; SNOMEDCT: 333606008; UMLS_CUI:C0034496
definition: A viral vaccine that protects against infection with Rabies virus.
imported from: vo.owl

Smallpox virus vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Variola virus
definition: A viral vaccine that protects against infection with Smallpox virus.
term editor: YH
see also: MeSH: D012900
imported from: vo.owl

Measles virus vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Measles virus
see also: MeSH: D008458
term editor: YH
definition: A viral vaccine that protects against infection with Measles virus.
alternative term: Measles vaccine
imported from: vo.owl

Rotavirus vaccine
type: Class
equivalent class: Class
  intersection of: viral vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Rotavirus
subclass of: viral vaccine
definition: A viral vaccine that protects against infection with Rotavirus.
term editor: YH
see also: MeSH: D022243; UMLS_CUI: C0597418; SNOMEDCT: 116077000
imported from: vo.owl

Haemophilus vaccine
type: Class
subclass of: vaccine
definition: A bacterial vaccine that protects against infection with Haemophilus.
term editor: YH
see also: MeSH: D018073
imported from: vo.owl

Haemophilus influenzae serotype b vaccine
type: Class
equivalent class: Class
  intersection of: Haemophilus influenzae vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Haemophilus influenzae serotype b
alternative term: Haemophilus b vaccine
term editor: YH
imported from: vo.owl

Poliovirus vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Dintheria
see also: MeSH: D023321
term editor: YH
definition: A viral vaccine that protects against infection with Poliovirus.
imported from: vo.owl

Japanese encephalitis virus vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Japanese encephalitis virus
alternative term: Japanese encephalitis vaccine
see also: MeSH: D022321
definition: A viral vaccine that protects against infection with Japanese encephalitis virus.
term editor: YH
imported from: vo.owl

human papillomavirus vaccine
type: Class
subclass of: viral vaccine
see also: UMLS_CUI: C1512511; SNOMEDCT: 424519000
definition: a vaccine against human papillomavirus infection
term editor: YH
imported from: vo.owl

Varicella-zoster virus vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Human herpesvirus 3
see also: UMLS_CUI: C0078048; SNOMEDCT: 108729007
definition: a Herpesvirus vaccine that is used against Varicella-zoster virus infection.
term editor: YH
alternative term: chickenpox virus vaccine
imported from: vo.owl

Salmonella typhi vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Salmonella enterica subsp. enterica serovar Typhi
alternative term: typhoid vaccine
definition: a Salmonella vaccine against typhoid fever (or called typoid), caused by Salmonella enterica enterica, serovar Typhi.
term editor: YH
imported from: vo.owl

Streptococcus pneumoniae vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Streptococcus pneumoniae
term editor: YH
definition: a Streptococcal vaccine that is used against S. pneumoniae infection, which causes pneumococcal diseases.
definition source: WEB: http://www.who.int/vaccines/en/pneumococcus.shtml
alternative term: pneumococcal vaccine
imported from: vo.owl

vaccine allergen disposition
type: Class
subclass of: disposition
term editor: YH
imported from: vo.owl

Measles-Mumps-Rubella vaccine
type: Class
subclass of: Measles-Mumps vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Rubella virus
alternative term: MMR
definition: A Measles-Mumps vaccine that also protects against infection with Rubella virus.
comment: MMR is usually live attenuated.
term editor: YH
imported from: vo.owl

Diphtheria-Tetanus vaccine
type: Class
subclass of: Corynebacterium diphtheriae vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Clostridium tetani
term editor: YH
definition: A Corynebacterium diphtheriae vaccine that also protect against infection with Clostridium tetani.
imported from: vo.owl

Corynebacterium diphtheriae vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Corynebacterium diphtheriae
alternative term: diphtheria vaccine
term editor: YH
definition: A bacterial vaccine that protects against infection with Corynebacterium diphtheriae that causes Diphtheria.
imported from: vo.owl

Measles-Mumps vaccine
type: Class
subclass of: Measles virus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Mumps virus
term editor: YH
definition: A Measles virus vaccine that also protects against infection with Mumps virus.
imported from: vo.owl

Measles-Mumps-Rubella-Vericella vaccine
type: Class
subclass of: Measles-Mumps-Rubella vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Human herpesvirus 3
term editor: YH
definition: A Measles-Mumps-Rubella vaccine that also protects against Vericella.
imported from: vo.owl

Diphtheria-Tetanus-Pertussis vaccine
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Bordetella pertussis
alternative term: DTP vaccine
term editor: YH
see also: UMLS_CUI: C0012559; SNOMEDCT: 421245007
alternative term: DTaP vaccine
imported from: vo.owl

Haemophilus influenzae serotype b
type: Class
subclass of: Gammaproteobacteria
term editor: YH
imported from: vo.owl

Diphtheria-Tetanus-Pertussis-Poliovirus vaccine
type: Class
subclass of: Diphtheria-Tetanus-Poliovirus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Dintheria
term editor: YH
imported from: vo.owl

Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Hepatitis B virus
term editor: YH
imported from: vo.owl

Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Haemophilus influenzae serotype b
term editor: YH
imported from: vo.owl

Hepatitis A&B vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Hepatitis A virus
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Hepatitis B virus
term editor: YH
imported from: vo.owl

Haemophilus b and Hepatitis B vaccine
type: Class
equivalent class: Class
  intersection of: Hepatitis B virus vaccine
  intersection of: Restriction
    on property: vaccine immunization against microbe
    some values from: Haemophilus influenzae serotype b
definition: a viral vaccine against Hepatitis B virus and at the same time against bacterial H. influenzae serotype b.
term editor: YH
imported from: vo.owl

Vibrio cholerae vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Vibrio cholerae
term editor: YH
alternative term: cholera vaccine
see also: MeSH: D022121
definition: A bacterial vaccine that prevents infection with Vibrio cholera.
imported from: vo.owl

BCG vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at some time
  some values from: bacterial vaccine organism live attenuated
alternative term: Bacillus Calmette Guerin
definition: BCG Vaccine is a Mycobacterium tuberculosis vaccine that is a live attenuated strain of Mycobacterium bovis (Bacillus Calmette Guerin; BCG).
see also: CVX: 19
term editor: YH
imported from: vo.owl

USA licensed vaccine role
type: Class
subclass of: licensed vaccine role
term editor: YH
definition: a licensed vaccine role that indicates the vaccine occurs in USA.
imported from: vo.owl

vaccine preservative
type: Class
equivalent class: Class
  intersection of: vaccine component
  intersection of: Restriction
    on property: has role at some time
    some values from: vaccine preservative role
alternative term: antimicrobial agent in vaccine
term editor: YH
imported from: vo.owl

vaccine stabilizer
type: Class
equivalent class: Class
  intersection of: vaccine component
  intersection of: Restriction
    on property: has role at some time
    some values from: vaccine stabilizer role
definition: a vaccine additive that helps to protect the vaccine from adverse conditions such as the freeze-drying process (for those vaccines that are freeze-dried) or heat.
definition source: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 75.
term editor: YH
imported from: vo.owl

cell culture residual in vaccine
type: Class
subclass of: vaccine component
definition: a vaccine residual that is generatead from cell culture for vaccine preparation. Examples include: antibiotics, sensitizing substances, bacterial and cellular residuals, and adventitious agents.
term editor: YH
definition source: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 78-81.
imported from: vo.owl

Canada licensed vaccine role
type: Class
subclass of: licensed vaccine role
term editor: YH
definition: a licensed status that occurs in Canada.
imported from: vo.owl

Fluviral S/F
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
term editor: YH
imported from: vo.owl

Influvac
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Solvay Pharmaceuticals
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
term editor: YH
definition: Influvac is an Influenza virus vaccine that is manufactured by Solvay Pharma.
imported from: vo.owl

Vaxigrip
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
term editor: YH, Melanie
definition: Vaxigrip is an Influenza virus vaccine that is manufactured by 'Sanofi Pasteur Limited.
imported from: vo.owl

aluminum vaccine adjuvant
type: Class
subclass of: vaccine adjuvant
term editor: YH
definition: a mineral salt vaccine adjuvant that is composed of aluminum salt.
term editor: Aluminum vaccine adjuvant is a vaccine adjuvant that is composed of some aluminum compound.
imported from: vo.owl

vaccine preservative role
type: Class
subclass of: vaccine additive role
definition source: P73 Chapter 6, Vaccine 5th edition by Plotkin, S. et al.
comment: The CFR requires that, with certain defined exceptions, preservatives must be added to mulitdose vials of vaccine. (P73 Chapter 6, Vaccine 5th edition by Plotkin, S. et al.)
term editor: YH,YL
definition: a role inhers in a vaccine component that when added into a vccine formmulation, it can prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during administrating process or the manufacturing process.
imported from: vo.owl

oral route
type: Class
subclass of: route of administration
subclass of: Restriction
  on property: located in at all times
  some values from: mouth
term editor: YH
term editor: a route of administration that located in the mouth
imported from: vo.owl

intradermal route
type: Class
subclass of: route of administration
subclass of: Restriction
  on property: located in at some time
  some values from: skin of body
alternative term: intradermal injection route
term editor: YH,YL
definition: a route of administration that inject the material(such as vaccines, allergens) into the skin itself.
has synonym: I.D.
imported from: vo.owl

phenol vaccine preservative
type: Class
subclass of: vaccine preservative
term editor: YH
imported from: vo.owl

phenoxy ethanol vaccine preservative
type: Class
subclass of: vaccine preservative
subclass of: Restriction
  on property: has role at some time
  some values from: vaccine preservative role
term editor: YH
imported from: vo.owl

vaccine allergen
type: Class
equivalent class: Class
  intersection of: material entity
  intersection of: Restriction
    on property: has disposition
    some values from: vaccine allergen disposition
definition source: WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
definition: vaccine allergen is a material entity that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals who has been vaccinated with a vaccine.
term editor: YH, ZX
imported from: vo.owl

latex vaccine allergen
type: Class
subclass of: vaccine allergen
term editor: YH, ZX
imported from: vo.owl

gelatin vaccine allergen
type: Class
subclass of: vaccine allergen
term editor: YH, ZX
imported from: vo.owl

protamine sulfate vaccine allergen
type: Class
subclass of: vaccine allergen
term editor: YH, ZX
imported from: vo.owl

bovine albumin cell culture residual in vaccine
type: Class
subclass of: cell culture residual in vaccine
definition: a cell culture residual in vaccine that is bovine albumin.
term editor: YH, ZX
imported from: vo.owl

bovine serum cell culture residual in vaccine
type: Class
subclass of: cell culture residual in vaccine
definition: a cell culture residual in vaccine that is bovine serum.
term editor: YH
imported from: vo.owl

monosodium glutamate stabliizer
type: Class
subclass of: vaccine stabilizer
subclass of: Restriction
  on property: has part
  some values from: monosodium glutamate
definition: a vaccine stablizer that is based on monosodium glutamate.
alternative term: C5H8NNaO4
comment: http://www.novaccine.com/vaccine-ingredients/results.asp
term editor: YL,YH
imported from: vo.owl

glutaraldehyde vaccine additive
type: Class
subclass of: vaccine preservative
subclass of: Restriction
  on property: has role at some time
  some values from: vaccine preservative role
imported from: vo.owl

human albumin cell culture residual in vaccine
type: Class
subclass of: cell culture residual in vaccine
definition: a cell culture residual in vaccine that is human albumin.
term editor: YH
imported from: vo.owl

human serum cell culture residual in vaccine
type: Class
subclass of: cell culture residual in vaccine
term editor: YH
definition: a cell culture residual in vaccine that is human serum.
imported from: vo.owl

polysorbate 20 vaccine stabilizer
type: Class
subclass of: vaccine stabilizer
subclass of: Restriction
  on property: has role at some time
  some values from: vaccine stabilizer role
definition: a vaccine stabilizer that is a polysorbate 20. It encourages the suspension of one liquid in another and has mild toxicity.
term editor: YH, YL
comment: http://www.novaccine.com/vaccine-ingredients/results.asp
comment: Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Reference: http://www.sciencelab.com/msds.php?msdsId=9926640
imported from: vo.owl

polysorbate 80 vaccine emulsifier
type: Class
subclass of: vaccine component
term editor: YH,YL
definition: a vaccine emulsifier that uses polysorbate 80, also known as polyoxyethylene sorbitan monooleate or Tween™ 80.
alternative term: Tween 80 vaccine emulsifier
comment: Tween 80 is an amber-colored, viscous liquid with a slightly bitter taste. The product is a derivative of sorbitol and oleic acid.
definition source: WEB: http://www.wisegeek.org/what-is-polysorbate-80.htm
imported from: vo.owl

vaccine residual protein from cell culture
type: Class
subclass of: cell culture residual in vaccine
term editor: YH
definition: a cell culture residual in vaccine that is residual protein from cell culture.
imported from: vo.owl

sorbitol vaccine stabilizer
type: Class
subclass of: vaccine stabilizer
subclass of: Restriction
  on property: has part
  some values from: glucitol
term editor: YH, YL
alternative term: glucitol
comment: Sorbitol, also known as glucitol, is a sugar alcohol that the human body metabolizes slowly. It can be obtained by reduction of glucose, changing the aldehyde group to a hydroxyl group. Sorbitol is found in apples, pears, peaches, and prunes. It is synthesized by sorbitol-6-phosphate dehydrogenase, and converted to fructose by succinate dehydrogenase and sorbitol dehydrogenase. Succinate dehydrogenase is an enzyme complex that participates in the citric acid cycle. (wikipedia)
definition: a vaccine stabilizer that is specifically made by sorbitol.
imported from: vo.owl

sucrose albumin cell culture residual in vaccine
type: Class
subclass of: cell culture residual in vaccine
definition: a cell culture residual in vaccine that is sucrose albumin.
term editor: YH
imported from: vo.owl

xanthan gum vaccine ajuvant
type: Class
subclass of: vaccine adjuvant
definition source: PMID: 19608270
term editor: YL
imported from: vo.owl

yeast extract cell culture residual in vaccine
type: Class
subclass of: cell culture residual in vaccine
term editor: YH
definition: a cell culture residual in vaccine that is from yeast extract.
imported from: vo.owl

yeast protein cell culture residual in vaccine
type: Class
subclass of: cell culture residual in vaccine
term editor: YH
definition: a cell culture residual in vaccine that is yeast protein.
imported from: vo.owl

Diphtheria-Tetanus-Pertussis-Haemophilus b vaccine
type: Class
subclass of: Diphtheria-Tetanus-Pertussis vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Haemophilus influenzae serotype b
imported from: vo.owl

Diphtheria-Tetanus-Poliovirus vaccine
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Dintheria
imported from: vo.owl

V. cholerae and E. coli vaccine
type: Class
subclass of: bacterial vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Escherichia coli
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Vibrio cholerae
imported from: vo.owl

Measles-Rubella vaccine
type: Class
subclass of: Measles virus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Rubella virus
definition: A Measles virus vaccine that is also used against Rubella virus infection.
definition: YH
imported from: vo.owl

Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Hepatitis B virus
imported from: vo.owl

Salmonella typhi-Hepatitis A vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Salmonella enterica subsp. enterica serovar Typhi
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Hepatitis A virus
imported from: vo.owl

Flublok
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Influenzavirus B
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
term editor: Yongqun He
comment: Trade Name: Flublok
imported from: vo.owl

Flucelvax
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Influenzavirus B
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Novartis
term editor: Yongqun He
comment: Trade Name: Flucelvax
imported from: vo.owl

FluMist Quadrivalent
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Influenzavirus B
subclass of: Restriction
  on property: is_manufactured_by
  has value: MedImmune Vaccines, Inc
subclass of: Restriction
  on property: vaccinated in route
  some values from: intranasal route by spray
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
term editor: YH
imported from: vo.owl

Fluarix Quadrivalent
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
term editor: YH
imported from: vo.owl

Tetanus Toxoid (for Boost use Only) by Sanofi Pasteur Inc
type: Class
subclass of: Clostridium tetani vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur, Inc
definition source: WEB: http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142732.pdf
term editor: YH
definition: a tetanus vaccine manusfactured by Sanofi Pasteur Inc. that is only for booster use (not recommended for primary immunization)
imported from: vo.owl

bacterial vaccine organism live attenuated
type: Class
equivalent class: Class
  intersection of: vaccine organism live attenuated
  intersection of: Restriction
    on property: inheres_in
    some values from: Bacteria
subclass of: vaccine organism live attenuated
term editor: YH
definition: a live attenuated quality of a bacterial vaccine strain.
imported from: vo.owl

viral vaccine organism live attenuated
type: Class
equivalent class: Class
  intersection of: vaccine organism live attenuated
  intersection of: Restriction
    on property: inheres_in
    some values from: Viruses
subclass of: vaccine organism live attenuated
term editor: YH
definition: a live attenuated quality of a virus vaccine strain.
imported from: vo.owl

Agriflu
type: Class
subclass of: Influenza virus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Novartis
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
see also: CVX: 140
term editor: YH
imported from: vo.owl

intramuscular vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: unfolds_in
  some values from: intramuscular route
definition: a vaccination that occurs in the intramuscular route.
term editor: YH, YL
imported from: vo.owl

Prevnar 13
type: Class
subclass of: polyvalent pneumococcal vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: Wyeth Pharmaceuticals Inc
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
term editor: ZX
see also: VIOLIN Vaccine ID: 1114
see also: CVX: 133
imported from: vo.owl

Menveo
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_manufactured_by
  has value: Novartis
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
see also: VIOLIN Vaccine ID: 1113
see also: CVX: 136
imported from: vo.owl

capsular polysaccharide of pathogen organism as vaccine component
type: Class
subclass of: part of pathogen organism in vaccine
term editor: YH
imported from: vo.owl

vaccine host role
type: Class
subclass of: role
subclass of: Restriction
  on property: inheres_in
  some values from: organism
definition: a role of host that contains vaccine. It is a role that inheres in an organism that is the target of a vaccine administration (vaccination process).
term editor: YH, ZX
imported from: vo.owl

vaccine target specification
type: Class
subclass of: objective specification
definition: The objective that intends to produce vaccine via the vaccine preparation process.
creator: YH
imported from: vo.owl

Influenza A (H1N1) 2009 Monovalent Vaccine (IDB)
type: Class
subclass of: H1N1 Influenza vaccine
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: is_distributed_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: ID Biomedical Corporation of Quebec
imported from: vo.owl

intradermal vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: unfolds_in
  some values from: intradermal route
creator: vaccination process that occurs in intradermal route.
creator: YL
imported from: vo.owl

intranasal vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: unfolds_in
  some values from: intranasal route
definition: vaccination process that occurs in intranasal route
creator: YL
imported from: vo.owl

oral vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: unfolds_in
  some values from: oral route
creator: YL
definition: vaccination process that occurs in oral route.
imported from: vo.owl

subcutaneous vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: unfolds_in
  some values from: subcutaneous route
creator: YL
definition: vaccination process that occurs in the subcutaneous route
imported from: vo.owl

vaccine emulsifier role
type: Class
subclass of: vaccine additive role
term editor: YL
definition: a role inheres in the vaccine component when it is added into vaccine's formulation, it tends to stabilizes an emulsion by increasing its kinetic stablity.
imported from: vo.owl

vaccine stabilizer role
type: Class
subclass of: vaccine additive role
term editor: YL
definition: a role inheres in vaccine component when added into vaccine's formulation, it tends to inhibit the reaction between two or more other vaccine substances in the final vaccine formulation; it also helps to protect the vaccine from adverse conditions such as the freeze-drying process or heat.
imported from: vo.owl

vaccine conjugate protein
type: Class
equivalent class: Class
  intersection of: vaccine component
  intersection of: Restriction
    on property: bearer_of
    some values from: vaccine conjugate role
subclass of: vaccine component
definition: The conjugate protein is a part of a conjugate vaccine and acts as a carrier protein that is covalently attached to a vaccine antigen with poor antigenicity (e.g., a polysaccharide). A conjugate protein is able to induce T-cell-dependent immune responses and stimulate the production of immune memory.
term editor: YL,YH
imported from: vo.owl

vaccine conjugate role
type: Class
subclass of: vaccine component role
creator: YL
definition: role inheres in a material eneitity that union itself chemically with a relative weak vaccine antigen to form a new whole that can create an effective miinuogen. The
imported from: vo.owl

percutaneous route
type: Class
subclass of: route of administration
term editor: YL
comment: epicutaneous (application onto the skin), e
imported from: vo.owl

percutaneous vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: unfolds_in
  some values from: percutaneous route
term editor: Administration of a drug by the way of absorption through the skin, usually for systemic action. The route allows sustained therapeutic plasma drug levels and avoids first pass effect. Simplicity of administration tends to result in high patient compliance.
term editor: YL
imported from: vo.owl

intravesical route
type: Class
subclass of: route of administration
subclass of: Restriction
  on property: located in at some time
  some values from: urinary bladder
imported from: vo.owl

intravesical vaccination
type: Class
subclass of: vaccination
subclass of: Restriction
  on property: unfolds_in
  some values from: intravesical route
definition: The injection of a given substance directly into the bladder via a urethral catheter instead of being injected under the skin.
term editor: YL
imported from: vo.owl

Actacel
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Haemophilus b vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
curator notes: todo: Proteins + Conjugate
comment: Trade Name: Actacel
term editor: YH, ZX
imported from: vo.owl

Avaxim
type: Class
subclass of: Hepatitis A virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
curator notes: todo: Killed virus
term editor: YH, ZX
comment: Trade Name: Avaxim
imported from: vo.owl

Avaxim - Pediatric
type: Class
subclass of: Hepatitis A virus vaccine
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
curator notes: todo: Killed virus
comment: Trade Name: Avaxim - Pediatric
term editor: YH, ZX
imported from: vo.owl

BCG Vaccine (Freeze-Dried) (by Sanofi Pasteur)
type: Class
subclass of: BCG vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
curator notes: todo: Live bacteria
comment: Trade Name: BCG Vaccine (Freeze-Dried)
term editor: YH, ZX
imported from: vo.owl

DT Polio Adsorbed
type: Class
subclass of: Diphtheria-Tetanus-Poliovirus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
curator notes: todo: Proteins + killed virus
term editor: YH, ZX
comment: Trade Name: DT Polio Adsorbed
imported from: vo.owl

Dukoral
type: Class
subclass of: V. cholerae and E. coli vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_distributed_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: is_manufactured_by
  has value: SBL Vaccine
curator notes: todo: Proteins + killed bacteria
term editor: YH, ZX
comment: Trade Name: Dukoral
imported from: vo.owl

Engerix-B
type: Class
subclass of: Hepatitis B virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has part
  some values from: yeast protein cell culture residual in vaccine
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
see also: CVX: 08
term editor: YH, ZX
see also: CVX: 44
comment: Product Name: Hepatitis B Vaccine (Recombinant)
comment: Trade Name: Engerix-B
imported from: vo.owl

Eolarix
type: Class
subclass of: Measles-Rubella vaccine
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: has part
  some values from: human albumin cell culture residual in vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has part
  some values from: dextran
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
term editor: YH, ZX
comment: Trade Name: Eolarix
definition: A Measles-Rubella vaccine that is live attenuated and manufactured by GlaxoSmithKline Biologicals.
imported from: vo.owl

Epaxal
type: Class
subclass of: Hepatitis A virus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: thimerosal vaccine preservative
subclass of: Restriction
  on property: is_manufactured_by
  has value: Berna Biotech, Ltd
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
curator notes: todo: Killed virus
term editor: YH, ZX
comment: Trade Name: Epaxal
imported from: vo.owl

FSME - IMMUN
type: Class
subclass of: Tick-borne Encephalitis Virus (TBEV) vaccine
subclass of: Restriction
  on property: has part
  some values from: sucrose albumin cell culture residual in vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gentamycin
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: has part
  some values from: human serum cell culture residual in vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: is_manufactured_by
  has value: Baxter Healthcare Corporation
subclass of: Restriction
  on property: has vaccine allergen
  some values from: protamine sulfate vaccine allergen
curator notes: todo: Inactivated whole virus
comment: Trade Name: FSME - IMMUN
term editor: YH, ZX
imported from: vo.owl

Hiberix
type: Class
subclass of: Haemophilus influenzae serotype b vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has role at all times
  some values from: conjugate vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
see also: CVX: 48
term editor: YH, ZX
comment: Trade Name: Hiberix
imported from: vo.owl

Imovax Polio
type: Class
subclass of: Poliovirus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: bovine serum cell culture residual in vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: streptomycin
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
curator notes: todo: Killed virus
term editor: YH, ZX
comment: Trade Name: Imovax Polio
imported from: vo.owl

Imovax Rabies (Canada)
type: Class
subclass of: Rabies virus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: human albumin cell culture residual in vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
term editor: YH, ZX
comment: Trade Name: Imovax Rabies
imported from: vo.owl

Inactivated Poliomyelitis Vaccine - IPV
type: Class
subclass of: Poliovirus vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has quality at all times
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has part
  some values from: bovine serum cell culture residual in vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
curator notes: todo: Killed virus
comment: Trade Name: Inactived Poliomyelitis Vaccine - IPV
term editor: YH, ZX
imported from: vo.owl

Infanrix-hexa
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has part
  some values from: yeast protein cell culture residual in vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has part
  some values from: polysorbate 20 vaccine stabilizer
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
curator notes: todo: Proteins + killed viruses + conjugate
comment: Trade Name: Infanrix-hexa
term editor: YH, ZX
imported from: vo.owl

Infanrix/Hib
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Haemophilus b vaccine
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
curator notes: todo: Proteins + conjugate
comment: Trade Name: Infanrix/Hib
term editor: YH, ZX
imported from: vo.owl

Infanrix-IPV
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus vaccine
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
curator notes: todo: Proteins + killed virus
comment: Trade Name: Infanrix-IPV
term editor: YH, ZX
imported from: vo.owl

Infanrix -IPV/Hib
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
curator notes: todo: Proteins + killed virus + conjugate
comment: Trade Name: Infanrix -IPV/Hib
term editor: YH, ZX
see also: CVX: 120
imported from: vo.owl

Liquid Pedvax HIB
type: Class
subclass of: Haemophilus influenzae serotype b vaccine
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck Frosst
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck & Co, Inc
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: vaccine conjugate protein
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
term editor: YH, ZX
comment: Trade Name: Liquid Pedvax HIB
imported from: vo.owl

Meningitec
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: is_manufactured_by
  has value: Berna Biotech, Ltd
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_distributed_by
  has value: Wyeth Canada
curator notes: todo: Conjugate
comment: Trade Name: Meningitec
term editor: YH, ZX
imported from: vo.owl

Meningococcal Polysaccharide Vaccine, Groups A & C, Menomune A/C
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
curator notes: todo: Polysaccharide
term editor: YH, ZX
comment: Trade Name: Meningococcal Polysaccharide Vaccine, Groups A & C, Menomune A/C
imported from: vo.owl

Menjugate
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Novartis Vaccines and Diagnostics
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
curator notes: todo: Conjugate
comment: Trade Name: Menjugate
term editor: YH, ZX
imported from: vo.owl

Menomune A/C/Y/W-135
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
curator notes: todo: Polysaccharide
term editor: YH, ZX
comment: Trade Name: Menomune A/C/Y/W-135
imported from: vo.owl

Mutacol
type: Class
subclass of: Vibrio cholerae vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Berna Biotech, Ltd
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: aspartame
subclass of: Restriction
  on property: has part
  some values from: yeast extract cell culture residual in vaccine
subclass of: Restriction
  on property: has part
  some values from: lactose
curator notes: todo: Live bacteria
term editor: YH, ZX
definition: A live attenuated V. cholerae vaccine that is manufactured by Berna Biotech, Ltd. This vaccine uses the V. Cholera strain CVD 103-HGR.
comment: Trade Name: Mutacol
imported from: vo.owl

Neisvac-C
type: Class
subclass of: Neisseria meningitidis vaccine
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Baxter Healthcare Corporation
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_distributed_by
  has value: GlaxoSmithKline Biologicals
curator notes: todo: Conjugate
comment: Trade Name: Neisvac-C
term editor: YH, ZX
imported from: vo.owl

Pediacel
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: bovine serum cell culture residual in vaccine
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: streptomycin
curator notes: todo: Proteins, killed virus + conjugate
comment: Trade Name: Pediacel
term editor: YH, ZX
imported from: vo.owl

Pneumo 23
type: Class
subclass of: polyvalent pneumococcal vaccine
subclass of: Restriction
  on property: has part
  some values from: phenol vaccine preservative
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: capsular polysaccharide of pathogen organism as vaccine component
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
curator notes: todo: Polysaccharide
term editor: YH, ZX
comment: Trade Name: Pneumo 23
imported from: vo.owl

Pneumovax 23 (Canada)
type: Class
subclass of: polyvalent pneumococcal vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck Frosst
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: phenol vaccine preservative
term editor: YH, ZX
comment: Trade Name: Pneumovax 23
imported from: vo.owl

Prevnar (Canada)
type: Class
subclass of: polyvalent pneumococcal vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Wyeth Canada
curator notes: todo: Conjugate
term editor: YH, ZX
comment: Trade Name: Prevnar
imported from: vo.owl

Priorix
type: Class
subclass of: Measles-Mumps-Rubella vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
term editor: YH, ZX
definition: A MMR vaccine that is manufactured by GlaxoSmithKline Biologicals.
comment: Trade Name: Priorix
imported from: vo.owl

Priorix-Tetra
type: Class
subclass of: Measles-Mumps-Rubella-Vericella vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
definition: A Measles-Mumps-Rubella-Vericella vaccine that is live attenuated and manufactured by GlaxoSmithKline Biologicals.
term editor: YH, ZX
comment: Trade Name: Priorix-Tetra
imported from: vo.owl

Quadracel
type: Class
subclass of: Diphtheria-Tetanus-Pertussis-Poliovirus vaccine
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: bovine albumin cell culture residual in vaccine
subclass of: Restriction
  on property: has part
  some values from: glutaraldehyde vaccine additive
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
curator notes: todo: Proteins + killed virus
comment: Trade Name: Quadracel
term editor: YH, ZX
imported from: vo.owl

Recombivax HB
type: Class
subclass of: Hepatitis B virus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck Frosst
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has part
  some values from: yeast protein cell culture residual in vaccine
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
curator notes: todo: Recombinant protein
see also: CVX: 08
see also: CVX: 44
see also: CVX: 43
term editor: YH, ZX
comment: Trade Name: Recombivax HB
imported from: vo.owl

Rotarix
type: Class
subclass of: Rotavirus vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: has part
  some values from: dextran
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: xanthan gum vaccine ajuvant
subclass of: Restriction
  on property: is_specified_input_of
  some values from: oral vaccination
subclass of: Restriction
  on property: has part
  some values from: sorbitol vaccine stabilizer
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
curator notes: todo: Live virus
term editor: YH, ZX
alternative term: ROTARIX
comment: Trade Name: Rotarix
imported from: vo.owl

Td Adsorbed
type: Class
subclass of: Diphtheria-Tetanus vaccine
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
curator notes: todo: Proteins
comment: Trade Name: Td Adsorbed
term editor: YH, ZX
imported from: vo.owl

Tripacel
type: Class
subclass of: Diphtheria-Tetanus-Pertussis vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has part
  some values from: glutaraldehyde vaccine additive
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
curator notes: todo: Proteins
term editor: YH, ZX
comment: Trade Name: Tripacel
imported from: vo.owl

Twinrix Junior
type: Class
subclass of: Hepatitis A&B vaccine
subclass of: Restriction
  on property: has part
  some values from: yeast protein cell culture residual in vaccine
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has part
  some values from: polysorbate 20 vaccine stabilizer
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
curator notes: todo: Recombinant protein + killed virus
term editor: YH, ZX
comment: Trade Name: Twinrix Junior
imported from: vo.owl

Typherix
type: Class
subclass of: Salmonella typhi vaccine
subclass of: Restriction
  on property: has part
  some values from: phenol vaccine preservative
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
curator notes: todo: Polysaccharide
term editor: YH, ZX
comment: Trade Name: Typherix
imported from: vo.owl

Vaqta
type: Class
subclass of: Hepatitis A virus vaccine
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: has part
  some values from: bovine albumin cell culture residual in vaccine
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has part
  some values from: vaccine residual protein from cell culture
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism inactivated
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck Frosst
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
curator notes: todo: Killed virus
comment: Trade Name: Vaqta
alternative term: VAQTA
term editor: YH, ZX
imported from: vo.owl

Varilrix
type: Class
subclass of: Varicella-zoster virus live vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has part
  some values from: human albumin cell culture residual in vaccine
subclass of: Restriction
  on property: has part
  some values from: lactose
subclass of: Restriction
  on property: has quality at some time
  some values from: vaccine organism live attenuated
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
subclass of: Restriction
  on property: has vaccine allergen
  some values from: latex vaccine allergen
curator notes: todo: Live virus
term editor: YH, ZX
comment: Trade Name: Varilrix
imported from: vo.owl

Varivax III
type: Class
subclass of: Varicella-zoster virus live vaccine
subclass of: Restriction
  on property: has part
  some values from: vaccine residual protein from cell culture
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: has part
  some values from: bovine serum cell culture residual in vaccine
subclass of: Restriction
  on property: has part
  some values from: monosodium glutamate stabliizer
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: is_manufactured_by
  has value: Merck Frosst
subclass of: Restriction
  on property: has part
  some values from: urea
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: sucrose
curator notes: todo: Live virus
comment: Trade Name: Varivax III
term editor: YH, ZX
imported from: vo.owl

ViVaxim
type: Class
subclass of: Salmonella typhi-Hepatitis A vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has part
  some values from: phenoxy ethanol vaccine preservative
subclass of: Restriction
  on property: has vaccine allergen
  some values from: neomycin
subclass of: Restriction
  on property: has part
  some values from: aluminum vaccine adjuvant
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: has part
  some values from: formaldehyde
subclass of: Restriction
  on property: has part
  some values from: polysorbate 80 vaccine emulsifier
subclass of: Restriction
  on property: is_manufactured_by
  has value: Sanofi Pasteur Limited
curator notes: todo: Polysaccharide + killed virus
editor note: todo: assign parent immunogen: Typh-I + (HA)
term editor: YH, ZX
comment: Trade Name: ViVaxim
imported from: vo.owl

Vivotif (Canada)
type: Class
subclass of: Salmonella typhi vaccine
subclass of: Restriction
  on property: has part
  some values from: aspartame
subclass of: Restriction
  on property: bearer_of
  some values from: Canada licensed vaccine role
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vaccine allergen
  some values from: gelatin vaccine allergen
subclass of: Restriction
  on property: is_manufactured_by
  has value: Berna Biotech, Ltd
subclass of: Restriction
  on property: has part
  some values from: lactose
curator notes: todo: Live virus
comment: Trade Name: Vivotif
term editor: YH, ZX
imported from: vo.owl

Ixiaro
type: Class
subclass of: Japanese encephalitis virus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: Intercell Biomedical
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
term editor: YH, ZX
see also: VIOLIN Vaccine ID: 741
see also: CVX: 134
imported from: vo.owl

Cervarix
type: Class
subclass of: human papillomavirus vaccine
subclass of: Restriction
  on property: vaccine immunization for host
  some values from: Homo sapiens
subclass of: Restriction
  on property: is_specified_input_of
  some values from: intramuscular vaccination
subclass of: Restriction
  on property: bearer_of
  some values from: USA licensed vaccine role
subclass of: Restriction
  on property: is_manufactured_by
  has value: GlaxoSmithKline Biologicals
see also: CVX: 118
term editor: YH, ZX
see also: VIOLIN Vaccine ID: 740
imported from: vo.owl

Haemophilus influenzae vaccine
type: Class
subclass of: Haemophilus vaccine
alternative term: Haemophilus influenzae
definition: A vaccine that protects against Haemophilus influenzae.
term editor: YH, ZX
imported from: vo.owl

Tick-borne Encephalitis Virus (TBEV) vaccine
type: Class
subclass of: viral vaccine
subclass of: Restriction
  on property: vaccine immunization against microbe
  some values from: Tick-borne encephalitis virus
definition: A vaccine that protects against Tick-borne Encephalitis Virus (TBEV).
alternative term: Tick-borne Encephalitis Virus (TBEV)
term editor: YH, ZX
imported from: vo.owl

nose structure
type: Class
subclass of: gross anatomical part
definition: *Subdivision of face which consists of the nasal skeleton, nasal septum and nasal cavity.
definition: 1a: The part of the face that bears the nostrils and covers the anterior part of the nasal cavity; broadly: this part together with the nasal cavity.n1b: The anterior part of the head at the top or end of the muzzle: snout, proboscis.n2: The vertebrate olfactory organ.
bioportal provenance: 1a: The part of the face that bears the nostrils and covers the anterior part of the nasal cavity; broadly: this part together with the nasal cavity.n1b: The anterior part of the head at the top or end of the muzzle: snout, proboscis.n2: The vertebrate olfactory organ.[accessedResource: BTO:0000840][accessDate: 05-04-2011]
definition: 1a: The part of the face that bears the nostrils and covers the anterior part of the nasal cavity; broadly: this part together with the nasal cavity.nb: The anterior part of the head at the top or end of the muzzle: snout, proboscis.n2. The vertebrate olfactory organ.
definition citation: AAO:0000334
definition: Any sense organ (FBbt:00005155) that functions in (some) detection of chemical stimulus involved in sensory perception (GO:0050907).
bioportal provenance: Any sense organ (FBbt:00005155) that functions in (some) detection of chemical stimulus involved in sensory perception (GO:0050907).[accessedResource: FBbt:00005157][accessDate: 05-04-2011]
definition: Any sense organ (FBbt:00005155) that has function 'detection of chemical stimulus involved in sensory perception (GO:0050907)'.
definition citation: BTO:0000840
definition citation: EHDAA:1502
definition citation: EMAPA:16542
definition citation: EV:0100037
definition citation: FBbt:00005157
definition citation: FMAID:46472
definition editor: James Malone
definition citation: MA:0000281
definition citation: MFO:0003640
bioportal provenance: Nose[accessedResource: FMAID:46472][accessDate: 05-04-2011]
definition citation: SAEL:72
definition citation: TAO:0001149
definition citation: XAO:0000201
definition citation: XAO:0003033
definition citation: ZFA:0001149
alternative term: chemosensory sensory organ
bioportal provenance: chemosensory sensory organ[accessedResource: FBbt:00005157][accessDate: 05-04-2011]
alternative term: nose
alternative term: olfactory system
bioportal provenance: olfactory system[accessedResource: TAO:0001149][accessDate: 05-04-2011]
imported from: vo.owl
imported from: efo.owl

State of California
type: NamedIndividual
type: geographic location
definition: A state on the West Coast of the United States, along the Pacific Ocean. It is bordered by Oregon to the north, Nevada to the east, Arizona to the southeast, and to the south the Mexican state of Baja California.
has_exact_synonym: CA
has_exact_synonym: Califor-nia
has_exact_synonym: California
has_obo_namespace: GAZ
id: GAZ:00002461
database_cross_reference: GNISID:01779778
database_cross_reference: INCITS38:06
database_cross_reference: ISO3166-2:US-CA
located_in: Pacific Division

Hawaiian Islands
type: NamedIndividual

State of New York
type: NamedIndividual
type: geographic location
has_obo_namespace: GAZ
id: GAZ:00002514
database_cross_reference: GNISID:01779796
database_cross_reference: INCITS38:36
database_cross_reference: ISO3166-2:US-NY
has_exact_synonym: NY
located_in: Middle Atlantic Division

State of Oregon
type: NamedIndividual
type: geographic location
definition: A state in the Pacific Northwest region of the United States. Oregon is located on the Pacific coast between Washington to the north, California to the south, Nevada on the southeast and Idaho to the east. The Columbia and Snake rivers delineate much of Oregon's northern and eastern boundaries respectively.
has_obo_namespace: GAZ
id: GAZ:00002515
database_cross_reference: INCITS38:41
database_cross_reference: ISO3166-2:US-OR
has_exact_synonym: OR
has_exact_synonym: Oregon
located_in: Pacific Division

State of Arizona
type: NamedIndividual
type: geographic location
definition: A state located in the southwestern region of the United States. It borders New Mexico, Utah, Nevada, California, touches Colorado, and has a 626 km international border with the States of Sonora and Baja California in Mexico.
has_exact_synonym: AZ
has_obo_namespace: GAZ
id: GAZ:00002518
database_cross_reference: GNISID:01779777
database_cross_reference: INCITS38:04
database_cross_reference: ISO3166-2:US-AZ
located_in: Mountain Division

State of Maryland
type: NamedIndividual
type: geographic location
definition: A state located in the Mid Atlantic region of the United States, bordering Virginia, West Virginia and the District of Columbia to the south and west, Pennsylvania to the north, and Delaware to the east.
has_obo_namespace: GAZ
id: GAZ:00002519
database_cross_reference: GNISID:01714934
database_cross_reference: INCITS38:24
database_cross_reference: ISO3166-2:US-MD
has_exact_synonym: MD
located_in: Middle Atlantic Division

State of North Carolina
type: NamedIndividual
type: geographic location
definition: A state located on the Atlantic Seaboard in the southeastern United States. The state borders South Carolina and Georgia to the south, Tennessee to the west and Virginia to the north.
has_obo_namespace: GAZ
id: GAZ:00002520
database_cross_reference: GNISID:01027616
database_cross_reference: INCITS38:37
database_cross_reference: ISO3166-2:US-NC
has_exact_synonym: NC
has_exact_synonym: North Carolina
located_in: South Atlantic Division

State of Alaska
type: NamedIndividual
type: geographic location
definition: A state in the United States of America, in the extreme northwest portion of the North American continent. The state is bordered by Yukon Territory and British Columbia, Canada to the east, the Gulf of Alaska and the Pacific Ocean to the south, the Bering Sea, Bering Strait, and Chukchi Sea to the west, and the Beaufort Sea and the Arctic Ocean.
has_exact_synonym: AK
has_obo_namespace: GAZ
id: GAZ:00002521
database_cross_reference: GNISID:01785533
database_cross_reference: INCITS38:02
database_cross_reference: ISO3166-2:US-AK
located_in: GAZ_00000458
located_in: United States of America

State of South Carolina
type: NamedIndividual
type: geographic location
definition: A state in the southern region (Deep South) of the United States. It borders Georgia to the south and North Carolina to the north.
has_obo_namespace: GAZ
id: GAZ:00002524
database_cross_reference: GNISID:01779799
database_cross_reference: INCITS38:45
database_cross_reference: ISO3166-2:US-SC
has_exact_synonym: SC
has_exact_synonym: South Carolina
located_in: South Atlantic Division

State of Rhode Island
type: NamedIndividual
type: geographic location
definition: A state in the New England region of the United States. By land Rhode Island borders Connecticut to the west and Massachusetts to the north and east. Rhode Island also shares a water border with New York to the southwest.
has_obo_namespace: GAZ
id: GAZ:00002531
database_cross_reference: GNISID:01219835
database_cross_reference: INCITS38:44
database_cross_reference: ISO3166-2:US-RI
has_exact_synonym: RI
has_exact_synonym: State of Rhode Island and Providence Plantations
located_in: New England Division

State of Wyoming
type: NamedIndividual
type: geographic location
definition: A state in the northwestern region of the United States. Wyoming is bordered on the north by Montana, on the east by South Dakota and Nebraska, on the south by Colorado, on the southwest by Utah, and on the west by Idaho.
has_obo_namespace: GAZ
id: GAZ:00002533
database_cross_reference: GNISID:01779807
database_cross_reference: INCITS38:56
database_cross_reference: ISO3166-2:US-WY
has_exact_synonym: WY
located_in: Mountain Division

Commonwealth of Massachusetts
type: NamedIndividual
type: geographic location
definition: A state located in the New England region of the northeastern United States. It borders Rhode Island and Connecticut to the south, New York to the west, and Vermont and New Hampshire to the north. To the east, it borders the Atlantic Ocean.
has_obo_namespace: GAZ
id: GAZ:00002537
database_cross_reference: ISO3166-2:US-MA
has_exact_synonym: MA
located_in: New England Division

State of Minnesota
type: NamedIndividual
type: geographic location
definition: A state in the Midwestern region of the United States. The state shares a Lake Superior water border with Michigan and Wisconsin on the northeast; the remainder of the eastern border is with Wisconsin. Iowa is to the south, North Dakota and South Dakota to the west, and the Canadian provinces of Ontario and Manitoba to the north.
has_obo_namespace: GAZ
id: GAZ:00002539
database_cross_reference: GNISID:00662849
database_cross_reference: INCITS38:27
database_cross_reference: ISO3166-2:US-MN
has_exact_synonym: MN
located_in: West North Central Division

Commonwealth of Pennsylvania
type: NamedIndividual
type: geographic location
definition: A state located in the Northeastern and Middle Atlantic regions of the United States. The state borders Delaware and Maryland to the south, West Virginia to the southwest, Ohio to the west, New York and Canada to the north, and New Jersey to the east.
has_obo_namespace: GAZ
id: GAZ:00002542
database_cross_reference: GNISID:01779798
database_cross_reference: INCITS38:42
database_cross_reference: ISO3166-2:US-PA
has_exact_synonym: PA
has_exact_synonym: Pennsylvania
has_exact_synonym: State of Pennsylvania
located_in: Middle Atlantic Division

State of Oklahoma
type: NamedIndividual
type: geographic location
definition: A state located in the South Central region and Southern Region of the United States of America. It is bounded on the east by Arkansas and Missouri, on the north by Kansas, on the northwest by Colorado, on the far west by New Mexico, and on the south and near-west by Texas.
has_obo_namespace: GAZ
id: GAZ:00002546
database_cross_reference: GNISID:01102857
database_cross_reference: INCITS38:40
database_cross_reference: ISO3166-2:US-OK
has_exact_synonym: OK
located_in: West South Central Division

State of Washington
type: NamedIndividual
type: geographic location
has_obo_namespace: GAZ
id: GAZ:00002553
database_cross_reference: GNISID:01779804
database_cross_reference: INCITS38:53
database_cross_reference: ISO3166-2:US-WA
definition: The Northwestern-most state of the contiguous United States. Its northern border lies mostly along the 49th parallel, and then via marine boundaries through the Strait of Georgia, Haro Strait and Strait of Juan de Fuca, with the Canadian province of British Columbia to the north. Washington borders Oregon to the south, with the Columbia River forming most of the boundary and the 46th parallel forming the eastern part of the southern boundary. To the east Washington borders Idaho, bounded mostly by the meridian running north from the confluence of the Snake River and Clearwater River, except for the southernmost section where the border follows the Snake River. To the west of Washington lies the Pacific Ocean.
has_exact_synonym: WA
has_exact_synonym: Washington
located_in: Pacific Division

State of New Jersey
type: NamedIndividual
type: geographic location
definition: A state in the Mid-Atlantic and Northeastern regions of the United States. It is bordered on the north by New York, on the east by the Atlantic Ocean, on the southwest by Delaware, and on the west by Pennsylvania. New Jersey lies within the sprawling metropolitan areas of New York and Philadelphia.
has_obo_namespace: GAZ
id: GAZ:00002557
database_cross_reference: GNISID:01779795
database_cross_reference: INCITS38:34
database_cross_reference: ISO3166-2:US-NJ
has_exact_synonym: NJ
located_in: Middle Atlantic Division

State of Texas
type: NamedIndividual
type: geographic location
definition: A state located in the South Central United States. The Rio Grande, Red River and Sabine River form natural state borders, Oklahoma on the north, Louisiana and Arkansas on the east, and the Mexican states of Chihuahua, Coahuila, Nuevo Leon, and Tamaulipas to the south.
has_obo_namespace: GAZ
id: GAZ:00002580
database_cross_reference: GNISID:01779801
database_cross_reference: INCITS38:48
database_cross_reference: ISO3166-2:US-TX
has_exact_synonym: TX
located_in: West South Central Division

State of Wisconsin
type: NamedIndividual
type: geographic location
definition: A State located in the north-central part of the United States. Wisconsin is bordered by the Montreal River; Lake Superior and Michigan to the north; by Lake Michigan to the east; by Illinois to the south; and by Iowa and Minnesota to the west. The state's boundaries include the Mississippi River and Saint Croix River in the west, and the Menominee River in the northeast Wisconsin's capital is Madison, and its largest city is Milwaukee.
has_obo_namespace: GAZ
id: GAZ:00002586
database_cross_reference: GNISID:01779806
database_cross_reference: INCITS38:55
database_cross_reference: ISO3166-2:US-WI
has_exact_synonym: WI
has_exact_synonym: Wisconsin
located_in: East North Central Division

State of Connecticut
type: NamedIndividual
type: geographic location
definition: A state located in the New England region of the northeastern United States of America. The state borders New York to the west and south (Long Island by sea), Massachusetts to the north, and Rhode Island to the east. Portions of southwestern Connecticut are considered part of the New York metropolitan area.
has_exact_synonym: CT
has_obo_namespace: GAZ
id: GAZ:00002591
database_cross_reference: GNISID:01779780
database_cross_reference: INCITS38:09
database_cross_reference: ISO3166-2:US-CT
located_in: New England Division

State of Maine
type: NamedIndividual
type: geographic location
definition: A state in the New England region of the northeastern United States of America, bordering the Atlantic Ocean to the southeast, New Hampshire to the southwest, the Canadian provinces of Quebec to the northwest and New Brunswick to the northeast.
has_obo_namespace: GAZ
id: GAZ:00002602
database_cross_reference: GNISID:01779787
database_cross_reference: INCITS38:23
database_cross_reference: ISO3166-2:US-ME
has_exact_synonym: ME
has_exact_synonym: Main
located_in: New England Division

State of Montana
type: NamedIndividual
type: geographic location
definition: A state in the Western United States. To the north, Montana and Canada share a 877 km border. The state borders the Canadian provinces of British Columbia, Alberta, and Saskatchewan. To the east, the state borders North Dakota and South Dakota. To the south is Wyoming and to the west and southwest is Idaho.
has_obo_namespace: GAZ
id: GAZ:00002606
database_cross_reference: GNISID:00767982
database_cross_reference: INCITS38:30
database_cross_reference: ISO3166-2:US-MT
has_exact_synonym: MT
located_in: Mountain Division

State of Georgia
type: NamedIndividual
type: geographic location
has_exact_synonym: GA
has_obo_namespace: GAZ
id: GAZ:00002611
database_cross_reference: GNISID:01705317
has_exact_synonym: Georgia
definition: Georgia is bordered on the south by Florida; on the east by the Atlantic Ocean and South Carolina; on the west by Alabama and by Florida in the extreme southwest; and on the north by Tennessee and North Carolina. The northern part of the state is in the Blue Ridge Mountains, a mountain range in the vast mountain system of the Appalachians. The central piedmont extends from the foothills to the fall line, where the rivers cascade down in elevation to the continental coastal plain of the southern part of the state.
database_cross_reference: INCITS38:13
database_cross_reference: ISO3166-2:US-GA
located_in: South Atlantic Division

State of Delaware
type: NamedIndividual
type: geographic location
definition: A state located on the Atlantic Coast in the Mid-Atlantic region of the United States. Delaware is located in the eastern section of the Delmarva Peninsula, between Delaware Bay and Chesapeake Bay. Delaware is bounded to the north by Pennsylvania; to the east by the Delaware River, Delaware Bay, New Jersey and the Atlantic Ocean; and to the west and south by Maryland.
has_exact_synonym: DE
has_obo_namespace: GAZ
id: GAZ:00002878
database_cross_reference: GNISID:01779781
database_cross_reference: INCITS38:10
database_cross_reference: ISO3166-2:US-DE
located_in: Middle Atlantic Division
located_in: Delmarva Peninsula

State of Florida
type: NamedIndividual
type: geographic location
definition: A state located in the southeastern region of the United States, bordering Alabama to the northwest and Georgia to the northeast. Much of the land mass of the state is a large peninsula with the Gulf of Mexico to the west and south, and the Atlantic Ocean to the east.
has_exact_synonym: Florida
has_exact_synonym: F{language: Bulgarian}
has_obo_namespace: GAZ
id: GAZ:00002888
database_cross_reference: GNISID:00294478
database_cross_reference: INCITS38:12
database_cross_reference: ISO3166-2:US-FL
located_in: South Atlantic Division

Middle Atlantic Division
type: NamedIndividual

East North Central Division
type: NamedIndividual

State of Illinois
type: NamedIndividual
type: geographic location
definition: A midwestern state of the United States of America. The Northeastern border of Illinois is Lake Michigan. Its eastern border with Indiana is all of the land west of the Wabash River, and a north-south line above Post Vincennes, or 87deg31min30secW. Its northern border with Wisconsin is fixed at 42deg30minN. Its western border with Missouri and Iowa is the Mississippi River. Its southern border with Kentucky is the Ohio River. Illinois also borders Michigan, but only via a water boundary in Lake Michigan.
has_obo_namespace: GAZ
id: GAZ:00003142
database_cross_reference: GNISID:01779784
database_cross_reference: INCITS38:17
database_cross_reference: ISO3166-2:US-IL
has_exact_synonym: Illinois
has_exact_synonym: I{language: Bulgarian}
located_in: East North Central Division

State of Michigan
type: NamedIndividual
type: geographic location
definition: A Midwestern state of the United States of America. Michigan consists of two peninsulas that lie between 82deg30minW to about 90deg30minW longitude, and are separated by the Straits of Mackinac. With the exception of two small areas that are drained by the Mississippi River by way of the Wisconsin River in the Upper Peninsula and by way of the Kankakee-Illinois River in the Lower Peninsula, Michigan is drained by the Great Lakes-Saint Lawrence watershed. The Great Lakes that border Michigan from east to west are Lake Erie, Lake Huron, Lake Michigan and Lake Superior. The state is bounded on the south by the states of Ohio and Indiana, sharing land and water boundaries with both.
has_obo_namespace: GAZ
id: GAZ:00003152
database_cross_reference: GNISID:01779789
database_cross_reference: INCITS38:26
database_cross_reference: ISO3166-2:US-MI
has_exact_synonym: MI
has_exact_synonym: Michigan
located_in: East North Central Division

Commonwealth of Virginia
type: NamedIndividual
type: geographic location
definition: A state on the Atlantic Coast of the Southern United States. Virginia is bordered by Maryland and the District of Columbia to the north and east; the Atlantic Ocean to the east; by North Carolina and Tennessee to the south; by Kentucky to the west and by West Virginia to the north and west. Due to a peculiarity of Virginia's original charter, its boundary with Maryland does not extend past the low-water mark of the southern shore of the Potomac River, so Maryland and the District of Columbia contain the whole width of the river rather than splitting it between them and Virginia. The southern border is defined as the 36deg30min parallel north.
has_obo_namespace: GAZ
id: GAZ:00003171
database_cross_reference: GNISID:01779803
database_cross_reference: INCITS38:51
database_cross_reference: ISO3166-2:UA-VA
has_exact_synonym: VA
has_exact_synonym: Virginia
located_in: South Atlantic Division

Pacific Division
type: NamedIndividual

West North Central Division
type: NamedIndividual

Greater Antilles
type: NamedIndividual

West South Central Division
type: NamedIndividual

East South Central Division
type: NamedIndividual

South Atlantic Division
type: NamedIndividual

Mountain Division
type: NamedIndividual

State of Hawaii
type: NamedIndividual
type: geographic location
definition: A state in the United States, located on an archipelago in the central Pacific Ocean southwest of the continental United States, southeast of Japan, and northeast of Australia.
has_obo_namespace: GAZ
id: GAZ:00003939
database_cross_reference: GNISID:01779782
has_exact_synonym: HI
database_cross_reference: INCITS38:15
database_cross_reference: ISO3166-2:US-HI
located_in: United States of America
located_in: Hawaiian Islands
located_in: Polynesia

Northern Mariana Islands
type: NamedIndividual

Virgin Islands Archipelago
type: NamedIndividual

State of Tennessee
type: NamedIndividual
type: geographic location
definition: A state located in the Southern United States. The capital city is Nashville, and the largest city is Memphis. Tennessee borders eight other states: Kentucky and Virginia to the north; North Carolina to the east; Georgia, Alabama and Mississippi on the south; Arkansas and Missouri on the Mississippi River to the west.
has_obo_namespace: GAZ
id: GAZ:00004411
database_cross_reference: GNISID:01325873
database_cross_reference: INCITS38:47
database_cross_reference: ISO3166-2:US-TN
has_exact_synonym: TN
has_exact_synonym: Tennessee
located_in: East South Central Division

State of Utah
type: NamedIndividual
type: geographic location
definition: A western state of the United States. Utah has three distinct geological regions: the Rocky Mountains, the Great Basin, and the Colorado Plateau.
has_obo_namespace: GAZ
id: GAZ:00004413
database_cross_reference: GNISID:01455989
database_cross_reference: INCITS38:49
database_cross_reference: ISO3166-2:US-UT
has_exact_synonym: UT
located_in: Mountain Division

State of West Virginia
type: NamedIndividual
type: geographic location
definition: A state in the Appalachian, Upland South, and Mid-Atlantic regions of the United States, bordered by Virginia on the southeast, Kentucky on the southwest, Ohio on the northwest, and Pennsylvania and Maryland on the northeast. The capital and largest city is Charleston.
has_obo_namespace: GAZ
id: GAZ:00004414
database_cross_reference: GNISID:01779805
database_cross_reference: INCITS38:54
database_cross_reference: ISO3166-2:US-WV
has_exact_synonym: WV
has_exact_synonym: West Virginia
located_in: South Atlantic Division

State of Ohio
type: NamedIndividual
type: geographic location
definition: A Midwestern state of the United States. Ohio's southern border is defined by the Ohio River (with the border being at the 1793 low-water mark on the north side of the river), and much of the northern border is defined by Lake Erie. Ohio's neighbors are Pennsylvania to the east, Michigan to the northwest, Ontario Canada, to the north, Indiana to the west, Kentucky on the south, and West Virginia on the southeast.
has_obo_namespace: GAZ
id: GAZ:00004421
database_cross_reference: GNISID:01085497
database_cross_reference: INCITS38:39
database_cross_reference: ISO3166-2:US-OH
has_exact_synonym: OH
has_exact_synonym: Ohio
located_in: East North Central Division

State of New Mexico
type: NamedIndividual
type: geographic location
definition: A state located in the southwestern region of the United States.
has_obo_namespace: GAZ
id: GAZ:00004427
database_cross_reference: GNISID:00897535
database_cross_reference: INCITS38:35
database_cross_reference: ISO3166-2:US-NM
has_exact_synonym: NM
located_in: Mountain Division

State of New Hampshire
type: NamedIndividual
type: geographic location
definition: A state in the New England region of the northeastern United States of America. It borders Massachusetts to the south, Vermont to the west, Maine to the east, and the Canadian province of Quebec to the north.
has_obo_namespace: GAZ
id: GAZ:00004428
database_cross_reference: GNISID:01779794
database_cross_reference: INCITS38:33
database_cross_reference: ISO3166-2:US-NH
has_exact_synonym: NH
located_in: New England Division

State of Vermont
type: NamedIndividual
type: geographic location
definition: A state in the New England region of the northeastern United States of America. It is bordered by Massachusetts to the south, New Hampshire to the east, New York to the west, and the Canadian province of Quebec to the north.
has_obo_namespace: GAZ
id: GAZ:00004429
database_cross_reference: GNISID:01779802
database_cross_reference: INCITS38:50
database_cross_reference: ISO3166-2:US-VT
has_exact_synonym: VT
located_in: New England Division

State of Mississippi
type: NamedIndividual
type: geographic location
definition: A state located in the Deep South of the United States. Jackson is the state capital and largest city. Mississippi is bordered on the north by Tennessee, on the east by Alabama, on the south by Louisiana and a narrow coast on the Gulf of Mexico, and on the west, across the Mississippi River, by Louisiana and Arkansas.
has_obo_namespace: GAZ
id: GAZ:00004430
database_cross_reference: GNISID:01779790
database_cross_reference: INCITS38:28
database_cross_reference: ISO3166-2:US-MS
has_exact_synonym: MS
has_exact_synonym: Mississippi
located_in: East South Central Division

State of Missouri
type: NamedIndividual
type: geographic location
definition: A state in the Midwest region of the United States. Missouri is bounded on the north by Iowa; on the east, across the Mississippi River, by Illinois, Kentucky, and Tennessee; on the south by Arkansas; and on the west by Oklahoma, Kansas, and Nebraska (the last across the Missouri River).
has_obo_namespace: GAZ
id: GAZ:00004431
database_cross_reference: GNISID:01779791
database_cross_reference: INCITS38:29
database_cross_reference: ISO3166-2:US-MO
has_exact_synonym: MO
located_in: West North Central Division

State of Louisiana
type: NamedIndividual
type: geographic location
definition: A state located in the southern region of the United States of America. Louisiana is bordered to the west by the State of Texas; to the north by Arkansas; to the east by the State of Mississippi; and to the south by the Gulf of Mexico.
has_obo_namespace: GAZ
id: GAZ:00004432
database_cross_reference: GNISID:01629543
database_cross_reference: INCITS38:22
database_cross_reference: ISO3166-2:US-LA
has_exact_synonym: LA
located_in: West South Central Division

State of Kansas
type: NamedIndividual
type: geographic location
definition: A state in the central region of the United States of America. Kansas is bordered by Nebraska on the north; Missouri on the east; Oklahoma on the south; and Colorado on the west.
has_obo_namespace: GAZ
id: GAZ:00004435
database_cross_reference: GNISID:00481813
database_cross_reference: INCITS38:20
database_cross_reference: ISO3166-2:US-KS
has_exact_synonym: KS
located_in: West North Central Division

State of Iowa
type: NamedIndividual
type: geographic location
definition: A state located in the Midwestern region of the United States of America. Iowa is bordered by the Mississippi River on the east; the Missouri River and the Big Sioux River on the west; the northern boundary is a line along 43 degrees, 30 minutes north latitude. The southern border is the Des Moines River and a line along approximately 40 degrees 35 minutes north.
has_obo_namespace: GAZ
id: GAZ:00004438
database_cross_reference: GNISID:01779785
has_exact_synonym: IA
database_cross_reference: INCITS38:19
database_cross_reference: ISO3166-2:US-IA
located_in: West North Central Division

State of Indiana
type: NamedIndividual
type: geographic location
definition: A midwestern state of the United States of America. Indiana is bounded on the north by Lake Michigan and the state of Michigan; on the east by Ohio; on the south by Kentucky, with which it shares the Ohio River as a border; and on the west by Illinois. Indiana is one of the Great Lakes states.
has_obo_namespace: GAZ
id: GAZ:00004439
database_cross_reference: GNISID:00448508
has_exact_synonym: IN
database_cross_reference: INCITS38:18
database_cross_reference: ISO3166-2:US-IN
has_exact_synonym: Indiana
located_in: East North Central Division

Commonwealth of Kentucky
type: NamedIndividual
type: geographic location
definition: A state located in the East Central United States of America. Kentucky borders on seven states, from both the Midwest and the Southeast. West Virginia lies to the east, Virginia to the southeast, Tennessee to the south, Missouri to the west, Illinois and Indiana to the northwest, and Ohio to the north and northeast.
has_obo_namespace: GAZ
id: GAZ:00004440
database_cross_reference: ISO3166-2:US-KY
has_exact_synonym: KY
has_exact_synonym: Kentucky
has_exact_synonym: State of Kentucky {alternative name}
located_in: East South Central Division

State of Arkansas
type: NamedIndividual
type: geographic location
definition: A state located in the southern region of the United States. Arkansas shares a border with six states, with its eastern border largely defined by the Mississippi River. Arkansas shares its southern border with Louisiana, its northern border with Missouri, its eastern border with Tennessee and Mississippi, and its western border with Texas and Oklahoma.
has_exact_synonym: AR
has_obo_namespace: GAZ
id: GAZ:00004441
database_cross_reference: GNISID:00068085
database_cross_reference: INCITS38:05
database_cross_reference: ISO3166-2:US-AR
located_in: West South Central Division

State of North Dakota
type: NamedIndividual
type: geographic location
definition: A state located in the Midwestern and Western regions of the United States of America.
has_obo_namespace: GAZ
id: GAZ:00004442
database_cross_reference: INCITS38:38
database_cross_reference: ISO3166-2:US-ND
has_exact_synonym: ND
located_in: West North Central Division

State of South Dakota
type: NamedIndividual
type: geographic location
definition: A state located in the Midwestern region of the United States of America.
has_obo_namespace: GAZ
id: GAZ:00004443
database_cross_reference: GNISID:01785534
database_cross_reference: INCITS38:46
database_cross_reference: ISO3166-2:US-SD
has_exact_synonym: SD
located_in: West North Central Division

State of Nevada
type: NamedIndividual
type: geographic location
definition: A state located in the western region of the United States of America. Nevada is almost entirely within the Basin and Range Province, and is broken up by many north-south mountain ranges. Most of these ranges have endorheic valleys between them, which belies the image portrayed by the term Great Basin. The southern third of the state, where the Las Vegas area is situated, is within the Mojave Desert.
has_obo_namespace: GAZ
id: GAZ:00004444
database_cross_reference: GNISID:01779793
database_cross_reference: INCITS38:32
database_cross_reference: ISO3166-2:US-NV
has_exact_synonym: NV
located_in: Mountain Division

State of Nebraska
type: NamedIndividual
type: geographic location
definition: A state located on the Great Plains of the Midwestern United States and Western United States.
has_obo_namespace: GAZ
id: GAZ:00005070
database_cross_reference: GNISID:01779792
database_cross_reference: INCITS38:31
database_cross_reference: ISO3166-2:US-NE
has_exact_synonym: NE
located_in: West North Central Division

Polynesia
type: NamedIndividual

Micronesia
type: NamedIndividual

State of Colorado
type: NamedIndividual
type: geographic location
definition: A state located in the Rocky Mountain region of the United States of America.
has_exact_synonym: CO
has_obo_namespace: GAZ
id: GAZ:00006254
database_cross_reference: GNISID:01779779
database_cross_reference: INCITS38:08
database_cross_reference: ISO3166-2:US-CO
located_in: Mountain Division

State of Idaho
type: NamedIndividual
type: geographic location
definition: A state in the Pacific Northwest region of the United States of America. Idaho borders six states and one Canadian province, but does not border the Pacific Ocean at any point and is not, as such, a coastal state. The states of Washington and Oregon are to the west, Nevada and Utah are to the south, and Montana and Wyoming are to the east. The province of British Columbia, to the north, also shares a small (77 km) border with Idaho.
has_obo_namespace: GAZ
id: GAZ:00006291
database_cross_reference: GNISID:01779783
has_exact_synonym: ID
database_cross_reference: INCITS38:16
database_cross_reference: ISO3166-2:US-ID
located_in: Mountain Division

New England Division
type: NamedIndividual

State of Alabama
type: NamedIndividual
type: geographic location
definition: A state located in the southern region of the United States of America. It is bordered by Tennessee to the north, Georgia to the east, Florida and the Gulf of Mexico to the south, and Mississippi to the west.
has_exact_synonym: Alabama
has_exact_synonym: A{language: Bulgarian}
has_obo_namespace: GAZ
id: GAZ:00006881
database_cross_reference: GNISID:01779775
database_cross_reference: INCITS38:01
database_cross_reference: ISO3166-2:US-AL
located_in: East South Central Division

Samoan Archipelago
type: NamedIndividual

Wake Island
type: NamedIndividual

Marshall Islands
type: NamedIndividual

Delmarva Peninsula
type: NamedIndividual
type: geographic location

Southern Marianas Islands
type: NamedIndividual

University of Maryland, College Park
type: NamedIndividual
type: organization
definition: A public research university located in the city of College Park in Prince George's County, Maryland.
has_obo_namespace: GAZ
id: GAZ:00157006
located_in: GAZ_00006320

example to be eventually removed
type: NamedIndividual
type: curation status specification
editor preferred term: example to be eventually removed

metadata complete
type: NamedIndividual
type: curation status specification
definition: Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete.
editor preferred term: metadata complete

organizational term
type: NamedIndividual
type: curation status specification
term editor: PERSON:Alan Ruttenberg
editor preferred term: organizational term
definition: term created to ease viewing/sort terms for development purpose, and will not be included in a release

ready for release
type: NamedIndividual
type: curation status specification
definition: Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release."
editor preferred term: ready for release
has curation status: pending final vetting

metadata incomplete
type: NamedIndividual
type: curation status specification
definition: Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors.
editor preferred term: metadata incomplete

uncurated
type: NamedIndividual
type: curation status specification
definition: Nothing done yet beyond assigning a unique class ID and proposing a preferred term.
editor preferred term: uncurated

pending final vetting
type: NamedIndividual
type: curation status specification
definition: All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor.
editor preferred term: pending final vetting

to be replaced with external ontology term
type: NamedIndividual
type: curation status specification
term editor: Alan Ruttenberg
definition: Terms with this status should eventually replaced with a term from another ontology.
definition source: group:OBI
editor preferred term: to be replaced with external ontology term

requires discussion
type: NamedIndividual
type: curation status specification
definition: A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues.
term editor: Alan Ruttenberg
definition source: group:OBI
editor preferred term: requires discussion

axiom holds for all times
type: NamedIndividual
editor preferred term: axiom holds for all times

Minatoba government Public Health division
type: NamedIndividual
type: organization

Rite Aid
type: NamedIndividual
type: company

Costco
type: NamedIndividual
type: company

Walgreens
type: NamedIndividual
type: company

Have you had a disorder in the last month that caused brain or nerve damage such as stroke or convulsion?
type: NamedIndividual
type: Class
  union of: question on stroke leading brain or nerve damage
  union of: question on convulsion leading brain or nerve damage

Intercell Biomedical
type: NamedIndividual
type: company

Acambis, Inc
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.acambis.com/

Berna Biotech, Ltd
type: NamedIndividual
type: company
has URI: http://www.crucell.com/
term editor: YH

BioPort Corp
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.bioport.com/

CSL Limited
type: NamedIndividual
type: company
has URI: http://www.csl.com.au/
term editor: YH

GlaxoSmithKline Biologicals
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.gsk-bio.com/english/index.html

Greer Laboratories Inc
type: NamedIndividual
type: company
has URI: http://www.greerlabs.com/
term editor: YH

ID Biomedical Corp of Quebec
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.ctidirectory.com/search/company.cfm

Massachusetts Public Health Biologic Lab
type: NamedIndividual
type: company
term editor: YH

MedImmune Vaccines, Inc
type: NamedIndividual
type: company
has URI: http://www.medimmune.com/
term editor: YH

Merck & Co, Inc
type: NamedIndividual
type: company
has URI: http://www.merck.com/
term editor: YH
alternative term: Merck Sharp & Dohme Corp.

Novartis Vaccines and Diagnostics
type: NamedIndividual
type: company
has URI: http://www.novartis.com/about-novartis/our-businesses/vaccines-diagnostic.shtml
term editor: YH

Organon Teknika Corp LLC
type: NamedIndividual
type: company
term editor: YH

Research Foundation for Microbial Diseases of Osaka University
type: NamedIndividual
type: company
has URI: http://read.jst.go.jp/public/cs_kkn_004EventAction.do
term editor: YH

Sanofi Pasteur Limited
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.sanofipasteur.com

Sanofi Pasteur, Inc
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.sanofipasteur.us
has_exact_synonym: Aventis Pasteur Inc.

Wyeth Pharmaceuticals Inc
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.wyeth.com/

Sanofi Pasteur, SA
type: NamedIndividual
type: company
term editor: YH
has URI: http://www.sanofipasteur.co.za/

Solvay Pharmaceuticals
type: NamedIndividual
type: company
term editor: YH

Baxter Healthcare Corporation
type: NamedIndividual
type: company
term editor: YH, ZX
has URI: http://www.baxter.com/

Merck Frosst
type: NamedIndividual
type: company
term editor: YH, ZX
has URI: http://www.merckfrosst.ca/

SBL Vaccine
type: NamedIndividual
type: company
term editor: YH, ZX

Wyeth Canada
type: NamedIndividual
type: company
has URI: http://www.wyeth.ca/
term editor: YH, ZX

Novartis
type: NamedIndividual
type: company
term editor: YH
alternative term: Aqua Health
has URI: http://www.novartis.com/

ID Biomedical Corporation of Quebec
type: NamedIndividual
type: company
creator: YL