patient_id,time_point,CD4_count,viral_load,hiv_diversity_pi,ab_diversity_pi,ab_divergence,hiv_synonymous_divergence,hiv_non_synonymous_divergence,hiv_selection_dN_dS,abr_baseline_mean_sigma_CDR,abr_baseline_mean_sigma_FWR
1,3.134246575,650,10921,0.962883074,31.42784051,0.025343316,0.003431918,0.009771407,0.897678174,-0.267096465,-0.626047382
1,3.597260274,638,10953,0.923537102,30.58687734,0.017401099,0.004464967,0.010485998,0.665737803,-0.424897436,-0.634765338
1,4.038356164,588,6776,1.030236894,33.34546146,0.033766187,0.010967445,0.008186044,0.587132954,0.067016208,-0.647559682
1,4.509589041,594,8282,1.664950215,30.62854942,0.03072828,0.02144313,0.013908429,0.668481704,-0.051294197,-0.497362125
1,4.939726027,504,8180,2.359579284,31.45303203,0.022937954,0.013804519,0.021766889,1.329512927,-0.259059035,-0.670731385
1,5.37260274,480,11219,1.013113077,33.06618029,0.041278368,0.02753884,0.022165023,0.892786492,0.109878325,-0.781401594
1,6.339726027,527,10369,3.336719573,33.06845236,0.03916407,0.032236368,0.034268363,1.241403925,-0.005876142,-0.580941297
1,6.761643836,530,12393,2.386692622,32.49247074,0.032470667,0.029811622,0.050361987,1.788219409,-0.035170866,-0.586913318
1,7.775342466,553,3748,1.420556338,30.9622112,0.025423737,0.029438954,0.043389359,1.537030342,-0.296303235,-0.509235234
1,8.78630137,462,3985,2.312157877,30.19324967,0.028966396,0.043628562,0.050026131,1.312444272,-0.005679978,-0.510372316
1,9.043835616,462,2513,4.980656284,32.89510597,0.024732189,0.057028981,0.042658621,1.05908435,-0.235467482,-0.683055702
1,9.632876712,400,9174,3.908967923,31.71970856,0.028645347,0.063160135,0.050499447,0.853462554,-0.207488574,-0.717251318
1,10.05205479,422,7655,4.109722179,32.99668486,0.046175176,0.070027695,0.061830139,0.943240244,-0.065406573,-0.775309244
1,10.49315068,469,6998,6.243090511,33.1681666,0.034083624,0.077590675,0.069690991,0.996994107,-0.078837026,-0.541306118
1,11,407,6351,5.241385215,31.31501605,0.034829487,0.04563295,0.049390097,1.651579772,-0.034298244,-0.573489768
1,11.46027397,354,8034,5.106067329,32.40244583,0.035162056,0.073951615,0.076666888,1.104567981,-0.13853098,-0.55418999
1,11.88219178,463,8576,NA,NA,NA,NA,NA,NA,NA,NA
1,12.32328767,NA,6074,2.429638373,31.38306512,0.024938877,0.08366321,0.080737896,0.986944971,-0.222589876,-0.624221247
1,12.76712329,377,10732,1.717734914,32.15417293,0.024681057,0.116208691,0.0929822,0.804067117,-0.131803255,-0.659684416
1,13.43287671,361,5551,4.302853265,31.9195419,0.032727179,0.050587386,0.077495352,1.649461183,-0.02063332,-0.600621653
1,14.36986301,NA,NA,NA,33.55786864,0.043449362,NA,NA,NA,0.05229394,-0.606128091
2,2.745205479,520,8828,1.316956761,30.63020186,0.05074184,0.029787229,0.008508336,0.285900939,-0.003463204,-0.77783611
2,3.145205479,391,9934,1.148209349,33.00126006,0.026016124,0.028081865,0.021967405,0.852368239,-0.091579265,-0.685207046
2,4.024657534,567,11900,1.787466782,33.39781293,0.033760821,0.018193731,0.03095216,1.700962169,0.1012852,-0.626537558
2,4.509589041,368,7026,1.790802817,32.22950985,0.024295536,0.030678953,0.041818922,1.415825804,0.053358696,-0.641258488
2,5.005479452,351,3565,2.06066574,32.16383597,0.019586797,0.033814167,0.068577922,2.242408836,-0.186683821,-0.717242142
2,5.449315068,317,6220,3.928410266,33.22997869,0.027391557,0.047406467,0.061760019,1.369855977,0.073454088,-0.635910267
2,5.945205479,350,12279,3.785100571,33.31775315,0.033616307,0.047198098,0.069764406,1.566392472,0.131170993,-0.616544825
2,6.964383562,336,15292,2.753306128,33.09033122,0.026094255,0.049463788,0.081525156,1.76573255,-0.007704933,-0.749593583
2,7.397260274,360,6322,2.350467311,32.56348663,0.023278955,0.054751754,0.089084306,1.822180658,-0.055608864,-0.798462486
2,7.750684932,340,5625,1.121208048,31.25649906,0.016967131,0.050760733,0.094362017,2.026559287,-0.123303977,-0.689944554
2,8.210958904,176,4734,2.205531425,31.74555522,0.02578669,0.054486073,0.100099013,1.974405769,0.1269517,-0.600845896
2,8.682191781,237,9101,0.148174358,31.37915793,0.020522666,0.053611645,0.106013731,2.060367691,-0.080693979,-0.676488696
2,9.301369863,189,11593,1.584406456,32.86482228,0.035537331,0.067149577,0.105428996,1.675328744,0.176757798,-0.591647614
2,10.50410959,176,39454,1.363059734,32.67917686,0.038789594,0.083094849,0.109266258,1.367922853,0.09302012,-0.668206682
2,10.96438356,139,29596,3.054054317,32.48181141,0.025192463,0.081434576,0.108395173,1.42436792,0.056207524,-0.705078075
2,11.43287671,110,103761,3.410130119,31.48490636,0.029114285,0.088192815,0.111931043,1.381522668,0.118806226,-0.408076769
2,12.75616438,NA,NA,NA,31.27132389,0.024495479,NA,NA,NA,0.022679057,-0.892745548
3,0.265753425,468,2221,0.047449332,29.47460691,0.014242464,0.000282585,0.000207769,0,-0.357771594,-0.624391373
3,0.734246575,448,3231,0.042142137,29.36624759,0.012599267,0.013644318,0.000204011,0.015066734,-0.432444182,-0.751816309
3,1.194520548,NA,1613,0.061852863,28.63114301,0.008329784,0.013842149,0.004012099,0.292305783,-0.662083794,-0.694745704
3,2.032876712,624,2109,0.743863572,NA,NA,0.026394386,0.001857208,0.061252022,NA,NA
3,2.589041096,476,6664,1.129648696,30.04415296,0.012903019,0.021229446,0.008442182,0.404289707,-0.494846196,-0.875943618
3,3.471232877,409,6549,1.150376726,29.13738406,0.011304102,0.040226297,0.008682105,0.261668371,-0.549365975,-0.616802045
3,3.947945205,403,3667,0.674232164,28.82893615,0.011571662,0.030484467,0.008995857,0.328854139,-0.462970982,-0.777494664
3,4.868493151,363,4932,1.811972999,28.55817962,0.012411633,0.035614685,0.016886386,0.550634013,-0.585655447,-0.612835723
3,5.731506849,384,7303,1.27073511,29.05499991,0.018074113,0.020002489,0.022864405,1.293578705,-0.315942979,-0.799855179
3,7.189041096,299,2585,2.366997304,30.61573159,0.016332178,0.027196213,0.040154759,1.892235443,-0.494823232,-0.816107691
4,0.197260274,950,1723,NA,33.60841293,0.04552731,NA,NA,NA,-0.03646416,-0.456966967
4,0.479452055,1116,1984,0.058345895,31.36586155,0.026122568,0.000390052,0.000269228,0.008019673,-0.194815728,-0.58890989
4,1.169863014,828,4813,0.305460468,31.80475096,0.030721244,0.026640714,0.01625455,0.608655559,-0.062243265,-0.610559828
4,2.093150685,713,20446,1.169835931,32.06802556,0.026445265,0.037462615,0.015289173,0.428712666,0.064507736,-0.486473972
4,2.495890411,707,2813,1.030319695,32.3559103,0.035076064,0.048370938,0.023252046,0.497725135,-0.011722417,-0.496007499
4,3.468493151,578,7710,1.440200983,32.16179555,0.031314085,0.041660105,0.034853006,0.892496439,-0.020633173,-0.538196995
4,4.424657534,692,6278,2.153188247,31.22325927,0.017334451,0.059304571,0.042936624,0.760283138,-0.257733638,-0.619946775
4,4.868493151,467,2944,2.356668756,33.01436461,0.038746636,0.077734484,0.051085287,0.66978532,0.080584945,-0.477979153
4,5.353424658,525,1849,0.064181983,31.83308039,0.03937085,0.105722779,0.060380244,0.552741169,-0.015193539,-0.638685016
4,6.232876712,446,4507,0.06106054,32.44487091,0.029330093,0.079297017,0.064148582,0.80084683,-0.008676885,-0.530346169
5,0.523287671,515,1324,0.065729784,30.70108964,0.015470772,0.000358183,0.000294974,0.002322547,-0.185848929,-0.613419058
5,0.6,601,1896,NA,NA,NA,NA,NA,NA,NA,NA
5,0.753424658,575,928,0.075744809,31.10135351,0.017834998,0.013439205,0.004110904,0.309529436,-0.227352118,-0.649760713
5,0.835616438,543,683,NA,31.8797135,0.022026407,NA,NA,NA,-0.11824099,-0.685754995
5,0.989041096,653,6803,0.06897661,33.27452404,0.042345092,0.00037037,0.004083942,0.291849159,0.07854869,-0.646449849
5,1.42739726,582,1229,0.070900994,31.31447234,0.019419985,0.000410947,0.007870202,0.58211336,-0.317151925,-0.704406397
5,1.906849315,308,8022,0.83638132,32.05157353,0.023276904,0.007828745,0.00736192,0.483504149,-0.165227933,-0.654871779
5,2.364383562,344,6489,0.987551553,32.26519443,0.037087242,0.005362904,0.012647952,0.847809328,0.284827546,-0.544443304
5,2.879452055,291,2852,0.423617759,31.84254336,0.020639913,0.001883393,0.015734042,1.239533864,-0.204547953,-0.709016857
5,3.301369863,180,3275,1.50909894,30.72423722,0.020621756,0.013333366,0.022116435,1.567827586,-0.25660189,-0.670602254
5,3.62739726,224,809,0.813276562,30.61352263,0.01548543,0.009316212,0.026738083,1.887868542,-0.463834858,-0.612809437
5,4.608219178,NA,NA,NA,30.84334399,0.018411575,NA,NA,NA,-0.283366156,-0.593886894
6,0.526027397,315,24721,0.511707487,31.38320433,0.018446474,0.002336586,0.003332664,0.159777215,-0.023768399,-0.544540502
6,1.189041096,364,67552,4.928474788,31.55282593,0.025527465,0.008079277,0.00778936,0.657991561,-0.024610666,-0.658401121
6,2.117808219,374,37108,1.119284472,31.49707466,0.019014375,0.00239226,0.005379747,0.438554345,-0.144879017,-0.665534902
6,3.032876712,275,79115,2.842810086,31.39724331,0.021176967,0.009626846,0.010890642,0.65656998,-0.03721762,-0.564936377
6,3.967123288,267,53101,2.688490269,31.26711719,0.017665401,0.018947888,0.013010371,0.807814382,-0.182680237,-0.560670045
6,4.890410959,159,52693,1.552643471,32.2578296,0.028918897,0.027907844,0.021818079,0.823247489,-0.058503308,-0.57974662
6,5.791780822,159,27492,2.298211764,32.48866906,0.033700188,0.027745711,0.01793108,0.729077709,-0.22541224,-0.386937004
6,6.731506849,103,30525,2.207475167,31.12833381,0.018608727,0.031240944,0.019463641,0.695570539,-0.387771958,-0.636854853
6,7.693150685,166,37537,NA,32.19249926,0.027834685,NA,NA,NA,-0.213171071,-0.467318014
6,8.553424658,151,72101,1.705444496,31.71038152,0.022279003,0.049153804,0.040276855,0.864631697,-0.305156594,-0.462049112
7,0.136986301,676,500000,0.293379715,32.09284542,0.010528102,0.000664597,0.000594011,0.003734733,-0.73101688,-1.059960824
7,0.410958904,1110,46498,0.230973239,31.53425013,0.011548783,0.004037112,0.000294304,0.014403802,0.010379746,-0.697697182
7,1.101369863,1082,4089,0.539997972,31.55667603,0.021379863,0.008956778,0.001603682,0.083714661,-0.096767668,-0.60761054
7,1.6,NA,6623,0.358785212,31.9525837,0.024032882,0.0001237,0.006660407,0.532233893,-0.120563275,-0.571081618
7,2.115068493,780,5267,0.826987662,31.49488659,0.0213341,0.008264741,0.007266776,0.467884766,-0.299146919,-0.686100254
7,2.597260274,726,7738,1.036456061,32.55631428,0.027946659,0.00398767,0.011934059,0.794354039,-0.163490025,-0.611848886
7,2.994520548,792,6641,0.998088226,32.46887089,0.025324223,0.012248546,0.021305264,1.431453539,-0.280161049,-0.630913488
7,3.454794521,786,7451,1.59408391,32.76187696,0.030103769,0.009402638,0.029665085,2.153319618,-0.235574029,-0.791629479
7,5.161643836,711,19298,1.731935981,31.97444057,0.023730205,0.013092254,0.033196866,2.194643323,-0.255377968,-0.747155528
7,6.679452055,515,20282,1.311545677,31.81055511,0.023215218,0.015382226,0.039512522,2.561415001,-0.24591256,-0.717611453
8,0.197260274,655,17185,0.386217015,32.36461921,0.028354276,0.004605104,0.001272277,0.111644573,0.1150189,-0.496095644
8,0.536986301,664,15093,0.880178289,33.00190024,0.035544616,0.004445306,0.009946749,0.718566603,0.005348092,-0.595519498
8,1.205479452,513,18421,1.092483752,33.16803854,0.047079004,0.000116299,0.015733547,1.059029654,0.111861614,-0.554446336
8,1.652054795,689,15697,0.59061237,33.49530454,0.043252021,0.013560605,0.018393672,1.299316641,-0.081099275,-0.5982362
8,2.112328767,439,6950,0.736573403,32.15648506,0.03515476,0.024591851,0.020361374,0.859261301,-0.201378317,-0.66762773
8,2.632876712,575,10120,0.852615333,31.80313185,0.033938679,0.023003459,0.022465792,1.09338332,-0.135891276,-0.541665281
8,3.046575342,529,9577,0.069243295,32.90410288,0.036030895,0.000391812,0.026407657,2.024548482,-0.113463966,-0.676594823
8,3.284931507,363,12231,0.0727297,32.99070303,0.037487924,0.000393498,0.033878959,2.629304762,-0.105038607,-0.61844981
8,3.723287671,418,14672,0.547998221,32.49996792,0.037083103,0.012681685,0.02472727,1.789068474,-0.103734287,-0.658924893
8,4.504109589,321,44503,1.231625208,30.5739057,0.024226973,0.007755678,0.032789105,2.333146846,-0.534094142,-0.866500498
9,0.216438356,574,2219,0.059591526,31.14313914,0.020094005,0.00032336,0.000287384,0.017517426,-0.214518501,-0.693673144
9,0.517808219,579,4375,0.069738129,30.64588308,0.019931541,0.01367974,0.007749255,0.569098678,-0.219761022,-0.530308493
9,1.230136986,503,5303,0.332578806,31.9011365,0.025078578,0.002552625,0.001577746,0.32337459,-0.155923209,-0.561981615
9,1.882191781,484,10119,0.509147706,33.06030842,0.039847582,0.023871073,0.001861089,0.084110608,-0.036450903,-0.626619999
9,2.131506849,519,28644,1.29450848,31.65403552,0.022910219,0.026081953,0.011031233,0.461718894,-0.152676729,-0.696467935
9,2.361643836,465,15767,0.072311027,32.99783229,0.036245786,0.013769473,0.011545796,0.847036098,-0.062917464,-0.636882534
9,2.8,460,26028,1.059759766,30.79606402,0.016620032,0.029650833,0.00901087,0.423789112,-0.385301148,-0.779705556
9,3.147945205,504,26391,1.261654627,30.86873656,0.016058172,0.025817715,0.00676213,0.315031046,-0.418106848,-0.808590829
9,3.509589041,423,22056,0.894860028,31.40652627,0.019681959,0.007562811,0.009155456,0.784317479,-0.363606965,-0.744407425
9,3.739726027,474,18817,0.45677677,30.87509539,0.017142556,0.025657205,0.025437307,1.029721532,-0.440396787,-0.799926598
10,0.065753425,803,41,NA,30.4010054,0.023473996,NA,NA,NA,-0.179140771,-0.564594161
10,0.304109589,1115,40,NA,32.61520026,0.04805921,NA,NA,NA,-0.05777739,-0.597351036
10,0.835616438,1009,40,NA,32.78095787,0.03781498,NA,NA,NA,-0.038566237,-0.580157506
10,1.065753425,1048,40,NA,33.10481989,0.04123612,NA,NA,NA,0.018570575,-0.610744361
10,1.523287671,959,40,NA,30.14418838,0.014330317,NA,NA,NA,-0.288326454,-0.596232338
10,1.98630137,944,40,NA,33.38391243,0.058418278,NA,NA,NA,0.036581985,-0.62942434
10,2.446575342,894,51,NA,30.4308189,0.025725826,NA,NA,NA,-0.030031647,-0.588650623
10,2.906849315,840,74,NA,30.22814509,0.027746901,NA,NA,NA,0.068284531,-0.520502398
10,3.367123288,1013,2977,0.058871495,29.67158476,0.035142618,0.000353231,0.000266206,0.00261076,0.578332896,-0.247450585
10,3.82739726,859,6312,0.291702847,30.13042032,0.025710872,0.000152282,0.006274879,0.472162659,-0.148697094,-0.568715804