--- name: peer-bench-med description: "Med peer benchmarking: select actual biotech/pharma peers via the med universe (drug/indication overlap where possible) and compare med-relevant metrics — pipeline depth, catalyst density, cash position, margins, valuation multiples." sectors: [med.medicines_biotech, med.medical_devices] multi_ticker_semantics: basket_v1_1 temporal_scope: default_quarters: 4 max_quarters: 12 description: "Benchmark window default 4 quarters; up to 12 for multi-year pipeline comparisons." allowed_tools: - search_companies - get_company_profile - search_xbrl_facts - get_financial_ratios - get_peer_comparison - get_company_drugs - search_drugs_by_target - search_drugs_by_indication - search_investment_cases - get_investment_case - search_investment_strategies - get_investment_strategy - search_by_analogue - search_knowledge_entries - get_knowledge_entry retrieval_scope: structured_only min_tool_diversity: 3 parameter_free: false --- > Methodology inspired by publicly taught peer-comparison frameworks; all text is an original paraphrase. ## Defaults | Parameter | Default Value | Rationale | |-----------|---------------|-----------| | peer_count | 4-6 | Comparable-set size standard for comps | | peer_logic | indication/drug overlap first | Med peers are defined by science, not SIC codes | | include_med_metrics | true | Pipeline depth, catalyst density, cash runway | ## Preflight Run canonical pre-flight per `contracts/preflight.md`. Include the `X-Agentii-Trace` header on every tool call per `contracts/x-agentii-trace-header.md` — carry the `_run_id` from your first tool result and name yourself (and your parent, if you were spawned). Never fabricate a peer metric when the data surface is absent — annotate `coverage_gap` instead (spec 055 FR-B02 discipline). ## Triggers - "Who are the closest peers to [biotech ticker]?" - "Benchmark [ticker] against its biotech comp set." - "How does [ticker]'s valuation compare to peers?" - "Which names compete with [ticker]'s pipeline?" - "Build a peer table with pipeline depth and cash." - "Is [ticker] expensive relative to its med peers?" - "Compare margins across the pharma peer group." - "What are the catalyst-dense names in this peer set?" - "Peer analysis for [ticker] with indication overlap." - "Which peers have the strongest balance sheets?" - "Which same-mechanism competitors matter for [ticker]'s pipeline?" ## Production Grounding - Med peers are science-defined: use `get_company_drugs` to find indication/therapy overlap before financial comparison. - Launch-analog selection: for commercial-stage names, match same-class (mechanism/indication class) + same-channel (specialty/retail/hospital/device-rep/vaccine-procurement) analogs so launch trajectories compare like-for-like. - Mechanism-overlap scoring: rank candidate peers by shared targets/indications via the drug-knowledge reverse lookups; where sources conflict, keep both values with provenance. - Med-relevant metrics: pipeline assets by phase, catalyst density (PDUFA/AdCom/trial readouts), cash runway (quarters), R&D productivity; generic margins only as secondary. - Grounding frameworks: `references/knowledge-frameworks.md` (道/法 review knowledge + valuation lenses). ## Data Source Priority 1. `get_company_drugs` / `search_companies` — peer discovery by drug/indication overlap. 2. `search_drugs_by_target` / `search_drugs_by_indication` — mechanism competitor mapping + overlap scoring (054 silver reverse lookups). 3. `get_financial_ratios` / `search_xbrl_facts` — financial comparison data. 4. `get_peer_comparison` — platform pre-computed peer metrics. 5. Knowledge layer: `search_investment_cases`/`search_by_analogue` for historical peer dynamics + launch analogs. ## Methodology ### Retrieval Scope structured_only ### Retrieval Strategy 1. Resolve the target via `get_company_profile`; pull its drugs (`get_company_drugs`). 2. Find peers by indication/therapy overlap + med industry membership (`search_companies`). 3. Map mechanism competitors: `search_drugs_by_indication` / `search_drugs_by_target` per key indication/target; score peers by shared targets/indications (conflicting sources shown with provenance). 4. Match launch analogs for commercial-stage names: same-class + same-channel; retrieve analog launch history via knowledge tools. 5. Pull per-peer financials (`get_financial_ratios`) + valuation context. 6. Ground with historical cases/analogues via knowledge tools. ### Temporal Scope See frontmatter temporal_scope block. ### Tool Allowlist See frontmatter allowed_tools. ### Protocol 1. Target profile 2. Science-based peer selection (indication/drug overlap) 3. Mechanism-overlap scoring (reverse lookups) 4. Launch-analog matching (same-class, same-channel) 5. Med-metric comparison 6. Valuation & risk synthesis ## Modes - **Science-based** (default): indication/drug-overlap peers. - **Launch-analog** (commercial-stage): same-class, same-channel analog peers with launch-trajectory context. - **Financial**: margin/valuation peers within the same industry. - **Catalyst**: peers ranked by upcoming FDA events. ## Tool Fallbacks | Failure | Fallback | |---------|----------| | get_company_drugs empty | Fall back to industry peers via `search_companies`; annotate | | Reverse lookups empty | Score overlap from `get_company_drugs` classes only; annotate mechanism mapping unavailable | | get_peer_comparison empty | Build comparison manually from `get_financial_ratios` | | Knowledge tools empty | Proceed with structured data only | ## Output File `{ticker}/{YYYY-MM-DD_HHMM}_peer-bench-med_{affix}.md` ## Output Structure 1. **Executive Summary** — relative standing in 2-3 sentences 2. **Peer Selection** — peers + selection logic (science overlap) 3. **Mechanism Overlap** — target/indication overlap matrix from reverse lookups, scored by shared mechanisms; conflicting source values shown with provenance 4. **Launch-Analog Match** — same-class, same-channel analogs (commercial-stage names) 5. **Comparison Table** — med metrics + financials + valuation 6. **Historical Context** — cases/analogues with /v/ citations 7. **Risk Assessment** — concentration/catalyst risks 8. **Coverage Gaps** — missing data flags ## Error Handling | Error | Fallback | |-------|----------| | No indication overlap found | Widen to same-industry peers; flag science-overlap unavailable | | Mechanism data missing | Score from indication overlap only; flag reverse-lookup coverage gap | | Missing financials | Mark N/A in table; do not fabricate | ## Memory Load See `contracts/memory-load.md`. ## Snapshot See `contracts/snapshot-synthesis.md`. ## Final Summary (TUI) Include ### Key Citations block with 0-10 clickable /v/ URLs. ## References - `contracts/citation-and-memory.md` - `contracts/output-frontmatter-schema.md` - `contracts/memory-load.md` - `contracts/snapshot-synthesis.md` - `contracts/preflight.md` - `references/knowledge-frameworks.md`