aid: a-alpha-bio
name: A-Alpha Bio
description: >-
  A-Alpha Bio is a Seattle biotechnology company, founded in 2017 out of the University of Washington's Institute for
  Protein Design and Center for Synthetic Biology, that measures, predicts and engineers protein-protein interactions.
  Its experimental platform AlphaSeq reprograms yeast mating to quantify millions of protein-protein binding affinities
  in a single experiment, and its computational platform AlphaBind is a domain-specific deep-learning model trained on
  hundreds of millions of those affinity measurements to predict and optimize antibody-antigen binding from sequence. In
  July 2026 the company launched Atlas, a web platform and data ecosystem that publishes ML-ready protein interaction
  "Data Blocks" for licensing, custom on-demand data generation, and a quarterly-release Atlas Consortium whose founding
  members include GSK, Boltz, Cradle and Dyno Therapeutics. Atlas is backed by a public HTTP API — the Data Product API
  at api.atlas.aalphabio.com — which serves dataset discovery, dataset metadata and structured Data Cards anonymously,
  and gates CSV data, CSV schemas and structure (.cif) files behind a bearer token issued through AWS Cognito sign-in.
url: https://raw.githubusercontent.com/api-evangelist/a-alpha-bio/refs/heads/main/apis.yml
image: https://www.aalphabio.com/icons/icon-512x512.png
x-type: company
x-source: harvest:secondary-market
specificationVersion: '0.23'
created: '2026-08-06'
modified: '2026-08-06'
tags:
- protein-interactions
- biotechnology
- drug-discovery
- antibody-engineering
- synthetic-biology
- machine-learning
- training-data
- data-licensing
- life-sciences
- datasets
- protein-design
- bioinformatics
apis:
- aid: a-alpha-bio:a-alpha-bio-datasets-api
  name: A-Alpha Bio Datasets API
  description: The Datasets API from A-Alpha Bio — 9 operation(s) for datasets.
  humanURL: https://atlas.aalphabio.com/
  baseURL: https://api.atlas.aalphabio.com
  tags:
  - Datasets
  properties:
  - type: OpenAPI
    url: openapi/a-alpha-bio-datasets-api-openapi.yml
  - type: Authentication
    url: authentication/a-alpha-bio-authentication.yml
  - type: Conventions
    url: conventions/a-alpha-bio-conventions.yml
  - type: ErrorCatalog
    url: errors/a-alpha-bio-problem-types.yml
  - type: DataModel
    url: data-model/a-alpha-bio-data-model.yml
  - type: JSONSchema
    url: json-schema/a-alpha-bio-dataset-item.json
  - type: JSONSchema
    url: json-schema/a-alpha-bio-datacard.json
  - type: JSONSchema
    url: json-schema/a-alpha-bio-dataset-schema.json
  - type: Examples
    url: examples/a-alpha-bio-list-datasets-response.json
  - type: Examples
    url: examples/a-alpha-bio-get-dataset-response.json
  - type: Examples
    url: examples/a-alpha-bio-get-dataset-datacard-response.json
  - type: Portal
    url: https://atlas.aalphabio.com/
common:
- type: Overlay
  url: overlays/a-alpha-bio-atlas-datasets-overlay.yaml
- type: IssueTracker
  url: https://github.com/A-Alpha-Bio/alphabind/issues
- type: License
  name: MIT
  url: https://github.com/A-Alpha-Bio/alphabind/blob/main/LICENSE
- type: DomainSecurity
  url: security/a-alpha-bio-domain-security.yml
- type: Website
  url: https://www.aalphabio.com/
- type: DeveloperPortal
  url: https://atlas.aalphabio.com/
- type: SignUp
  url: https://atlas.aalphabio.com/
- type: Login
  url: https://atlas.aalphabio.com/
- type: Blog
  url: https://aalphabio.substack.com/
- type: BlogRSS
  url: https://aalphabio.substack.com/feed
- type: News
  url: https://www.aalphabio.com/media/
- type: GitHubOrganization
  url: https://github.com/A-Alpha-Bio
- type: Support
  url: https://www.aalphabio.com/contact/
- type: TermsOfService
  url: https://www.aalphabio.com/terms-of-service/
- type: PrivacyPolicy
  url: https://www.aalphabio.com/privacy-notice/
- type: About
  url: https://www.aalphabio.com/about/
- type: Careers
  url: https://www.aalphabio.com/careers/
- type: Twitter
  url: https://twitter.com/AAlphaBio
- type: LinkedIn
  url: https://linkedin.com/company/aalphabio/
- type: SourceCode
  url: https://github.com/A-Alpha-Bio/alphabind
- type: Authentication
  url: authentication/a-alpha-bio-authentication.yml
- type: Conventions
  url: conventions/a-alpha-bio-conventions.yml
- type: ErrorCatalog
  url: errors/a-alpha-bio-problem-types.yml
- type: Lifecycle
  url: lifecycle/a-alpha-bio-lifecycle.yml
- type: Conformance
  url: conformance/a-alpha-bio-conformance.yml
- type: DataModel
  url: data-model/a-alpha-bio-data-model.yml
- type: CLI
  url: cli/a-alpha-bio-cli.yml
- type: MCPServer
  url: mcp/a-alpha-bio-mcp.yml
- type: LLMsTxt
  url: llms/a-alpha-bio-llms.txt
- type: AgentSkill
  url: skills/_index.yml
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
x-enrichment:
  date: '2026-08-06'
  status: enriched
  artifacts_added: 23
  pass: local-v1