# Alloplex Biotherapeutics

> Alloplex Biotherapeutics, Inc. is a privately held clinical-stage cellular immunotherapy company
> founded in 2016 and headquartered in Woburn, Massachusetts, with a wholly owned subsidiary,
> Alloplex Australia Pty Ltd, in Adelaide, South Australia. It develops non-engineered, autologous
> multi-cellular therapies intended to retrain a patient's own immune system against solid tumors
> and autoimmunity. Its ENLIST platform uses an irradiated, engineered melanoma cell line expressing
> multiple immunomodulatory factors to activate, differentiate and expand a patient's peripheral
> blood mononuclear cells; the resulting product, SUPLEXA, is manufactured by a defined,
> GMP-compatible process using no genetic engineering and no feeder cells. The first-in-human Phase 1
> SUPLEXA-101 trial in Australia (35 patients with metastatic solid tumors) met its endpoints, and
> the FDA granted SUPLEXA Fast Track designation for MSI-H colorectal cancer.

**This file was generated by API Evangelist, not by Alloplex Biotherapeutics.** The company does not
publish an llms.txt; `https://alloplexbio.com/llms.txt` returns 404.

## What API surface exists

Alloplex Biotherapeutics runs **no developer program**. There is no product API, no developer
portal, no API documentation, no SDK, no CLI, no sandbox, no OpenAPI, no status page and no support
channel for developers. `/developers/`, `/api/`, `/docs/` and every `/.well-known/` path return 404,
verified against a negative control.

The **only** machine-readable surface reachable without credentials is the WordPress REST content
API behind the corporate site — the CMS's own content surface, not a product:

- Base URL: https://alloplexbio.com/wp-json
- Anonymous, read-only. The REST index returns `"authentication": []`.
- 219 routes across 12 namespaces; 19 operations return data without credentials.
- Contents at harvest: 61 posts, 19 pages, 225 media items, 11 category terms, 0 tags.
- Upstream contract: https://developer.wordpress.org/rest-api/

Two agent-shaped surfaces are **registered but gated**: a WordPress MCP adapter endpoint
(`POST /wp-json/mcp/mcp-adapter-default-server`) and the WordPress Abilities API
(`wp-abilities/v1`). Both return `401 rest_forbidden` anonymously, so no MCP server and no agent
capability registry is claimed for this provider. No A2A agent card is published.

## Specs

- [OpenAPI 3.1 — Content API](openapi/alloplex-biotherapeutics-content-openapi.yml): API Evangelist derivation of the published WordPress route index, restricted to operations verified to return data anonymously on 2026-08-06.
- [Overlay](overlays/alloplex-biotherapeutics-content-overlay.yaml): records exactly which enhancements API Evangelist added on top of the bare route index.
- [JSON-LD](json-ld/alloplex-biotherapeutics-organization.jsonld): the schema.org graph the site publishes in HTML, saved verbatim. Not projected into the REST API.

## Artifacts

- [Authentication](authentication/alloplex-biotherapeutics-authentication.yml): no schemes declared; what is open and what returns 401.
- [Conventions](conventions/alloplex-biotherapeutics-conventions.yml): pagination, sparse fieldsets, caching, error envelope, versioning.
- [Error catalog](errors/alloplex-biotherapeutics-problem-types.yml): the WordPress error envelope — NOT RFC 9457.
- [Data model](data-model/alloplex-biotherapeutics-data-model.yml): entity graph, including the broken `author` edge and the four entities missing from the API.
- [Lifecycle](lifecycle/alloplex-biotherapeutics-lifecycle.yml): no versioning policy, no deprecation policy, no SLA, no status page.
- [Conformance](conformance/alloplex-biotherapeutics-conformance.yml): standards the surface does and does not meet.
- [Well-known](well-known/alloplex-biotherapeutics-well-known.yml): every RFC 8615 path probed, all 404, with a negative control.
- [Domain security](security/alloplex-biotherapeutics-domain-security.yml): TLS 1.3, no HSTS, no DNSSEC, no CAA, SPF present, DMARC p=none.
- [Agent skills](skills/_index.yml): three packaged operating instructions grounded in real operationIds.

## Using the content API

- `GET /wp/v2/posts` — 61 press releases, clinical/scientific news, conference notes, opinion pieces. `content.rendered` is fully populated.
- `GET /wp/v2/pages` — 19 corporate pages. All top-level. The FAQ page (1019) returns an empty body.
- `GET /wp/v2/media` — 225 attachments including PDF documents.
- `GET /wp/v2/categories` — 11 terms carrying all editorial grouping.
- `GET /wp/v2/search?search=SUPLEXA` — cross-content search.
- Pagination totals are in the `X-WP-Total` / `X-WP-TotalPages` headers, never in the body.
- `_fields` is the most useful parameter for controlling payload size.

### Known gaps an agent should not trip on

- The `tags` taxonomy is registered but empty — group by `categories`.
- `author` is a populated integer but unresolvable: `/wp/v2/users` returns 401.
- The site's sitemaps advertise `publication`, `team_member`, `conference` and `resource` types that
  are **not** REST-registered — requesting them returns `404 rest_no_route`. Scientific publications,
  leadership bios and conference appearances are HTML-only.
- No rate-limit headers. `robots.txt` requests `Crawl-delay: 10`.

## Company pages

- [Home](https://alloplexbio.com/)
- [About Alloplex](https://alloplexbio.com/about/)
- [The science of retrained immunity](https://alloplexbio.com/scientists/)
- [Investors](https://alloplexbio.com/investors/)
- [Information for patients](https://alloplexbio.com/information-for-patients/)
- [Releases and updates](https://alloplexbio.com/releases-and-updates/)
- [Media and press](https://alloplexbio.com/newsroom/)
- [In the news](https://alloplexbio.com/in-the-news/)
- [Media kit](https://alloplexbio.com/presskitoct24/)
- [Publications](https://alloplexbio.com/publications/)
- [FAQ](https://alloplexbio.com/faq/)
- [Contact](https://alloplexbio.com/contact/)
- [Terms of use](https://alloplexbio.com/terms/)
- [Privacy policy](https://alloplexbio.com/privacy-policy/)
- [RSS feed](https://alloplexbio.com/feed/)
- [Sitemap index](https://alloplexbio.com/sitemap_index.xml)