aid: arc-institute
name: Arc Institute
description: >-
  Arc Institute is an independent nonprofit biomedical research organization
  headquartered in Palo Alto, California, co-founded in 2021 by Silvana
  Konermann (Executive Director), Patrick Hsu (Core Investigator), and Stripe
  co-founder Patrick Collison. With 300+ staff ("Arconauts") across 9 core
  laboratories and 5 technology centers, Arc develops AI foundation models
  for biology that span DNA, RNA, proteins, and single cells. Its flagship
  releases include Evo (Science, 2024) and Evo 2 (Nature, 2026) — DNA
  foundation models trained on trillions of nucleotides at single-nucleotide
  resolution with up to a 1-megabase context; STATE and Stack single-cell
  foundation models for cellular perturbation and in-context learning; the
  Arc Virtual Cell Atlas; the SRAgent LLM agents for bioinformatics; and the
  BINSEQ binary sequencing format. Models are released under Apache 2.0 on
  GitHub and Hugging Face, with hosted inference for Evo 2 available through
  NVIDIA BioNeMo and the NVIDIA build.nvidia.com API. Arc is funded by
  philanthropic donations from Patrick and John Collison, Vitalik Buterin,
  the Ron Conway family, Dustin Moskovitz, Daniel Gross, Elad Gil, and other
  technology benefactors; it does not sell APIs, SaaS, or models commercially.
type: Index
position: Provider
access: 3rd-Party
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
tags:
  - Biomedical Research
  - Computational Biology
  - Genomics
  - DNA Foundation Models
  - Foundation Models
  - Single Cell
  - Protein Engineering
  - Evo
  - Evo 2
  - Bioinformatics
  - Nonprofit
  - Open Source
  - Machine Learning
  - AI for Science
url: https://raw.githubusercontent.com/api-evangelist/arc-institute/refs/heads/main/apis.yml
created: '2026-05-24'
modified: '2026-05-24'
specificationVersion: '0.20'
apis: []
common:
  - type: DomainSecurity
    url: security/arc-institute-domain-security.yml
  - type: Website
    url: https://arcinstitute.org
  - type: About
    url: https://arcinstitute.org/about
  - type: Programs
    url: https://arcinstitute.org/programs
  - type: Tools
    url: https://arcinstitute.org/tools
  - type: Models
    url: https://arcinstitute.org/model
  - type: News
    url: https://arcinstitute.org/news
  - type: Publications
    url: https://arcinstitute.org/publications
  - type: Careers
    url: https://arcinstitute.org/jobs
  - type: GitHubOrganization
    url: https://github.com/arcinstitute
  - type: HuggingFace
    url: https://huggingface.co/arcinstitute
  - type: Evo
    url: https://github.com/evo-design/evo
  - type: Evo2
    url: https://github.com/arcinstitute/evo2
  - type: HostedAPI
    url: https://build.nvidia.com/arc/evo2-40b
  - type: BioNeMo
    url: https://docs.nvidia.com/bionemo-framework/latest/models/evo2.html
  - type: Paper
    url: https://doi.org/10.1038/s41586-026-10176-5
  - type: Paper
    url: https://www.science.org/doi/10.1126/science.ado9336
  - type: LinkedIn
    url: https://www.linkedin.com/company/arc-institute
  - type: Twitter
    url: https://twitter.com/arcinstitute
  - type: YouTube
    url: https://www.youtube.com/@arcinstitute
  - type: Blog
    url: https://arcinstitute.org/news
maintainers:
  - FN: Kin Lane
    email: kin@apievangelist.com