aid: biosplice-therapeutics name: Biosplice Therapeutics description: >- Biosplice Therapeutics, Inc. is a privately held, clinical-stage biopharmaceutical company headquartered in San Diego, California, founded in 2008 by Osman Kibar and known until its 2020 rename as Samumed, LLC (samumed.com still redirects to biosplice.com). The company develops first-in-class small-molecule therapeutics that act on novel components of the Wnt signaling pathway and on the regulation of alternative pre-mRNA splicing. Its lead program is lorecivivint, an investigational intra-articular knee injection for osteoarthritis, positioned against a stated unmet need of "over 50 million US patients suffer from osteoarthritis, with no drugs available to arrest the disease"; the candidate has completed Phase 3 study and a New Drug Application has been submitted to the U.S. Food and Drug Administration. Programs outside lorecivivint — neurology, diabetes and oncology — are developed by the company's affiliate TenaRx, Inc. The company is led by Erich Horsley (Chief Executive Officer) with Osman Kibar as Founder and Executive Chairman, Yusuf Yazici as Chief Medical Officer, Phil Wilson as Chief Financial Officer and Scott W. Bulcao as Chief Legal Officer. Biosplice is a drug-discovery and clinical-development organization, not a software vendor: biosplice.com is a small ASP.NET corporate site covering mission, board, management, advisors, programs, publications, news and careers, and the company publishes no developer program of any kind — no API, no SDK, no developer portal, no GitHub organization and no machine-readable API contract. url: https://raw.githubusercontent.com/api-evangelist/biosplice-therapeutics/refs/heads/main/apis.yml x-type: company x-source: harvest:secondary-market x-tier: stub x-tier-reason: harvest specificationVersion: '0.23' created: '2026-08-07' modified: '2026-08-07' tags: - Company - Biotechnology - Pharmaceuticals - Life Sciences - Drug Development - Clinical Trials - Osteoarthritis - Small Molecule Therapeutics - Health Care - San Diego apis: [] maintainers: - FN: Kin Lane email: kin@apievangelist.com - FN: APIs.json email: info@apis.io common: - type: DomainSecurity url: security/biosplice-therapeutics-domain-security.yml - type: WellKnown url: well-known/biosplice-therapeutics-well-known.yml - type: LLMsTxt url: llms/biosplice-therapeutics-llms.txt - type: Website url: https://www.biosplice.com/ - type: About url: https://www.biosplice.com/mission/default.aspx - type: Pipeline url: https://www.biosplice.com/our-programs/detail.aspx?id=20 - type: Team url: https://www.biosplice.com/management/default.aspx - type: Publications url: https://www.biosplice.com/publications/default.aspx - type: News url: https://www.biosplice.com/news/default.aspx - type: Blog url: https://www.biosplice.com/news/default.aspx - type: Careers url: https://www.biosplice.com/careers/default.aspx - type: Contact url: https://www.biosplice.com/contact-us/default.aspx - type: Support url: https://www.biosplice.com/contact-us/default.aspx - type: PrivacyPolicy url: https://www.biosplice.com/privacy/default.aspx - type: TermsOfService url: https://www.biosplice.com/terms/default.aspx - type: LinkedIn url: https://www.linkedin.com/company/biospliceinc - type: SecondaryMarket url: https://forgeglobal.com/biosplice-therapeutics_stock/ x-enrichment: date: '2026-08-07' status: minimal artifacts_added: 3 pass: local-v1 x-coverage: state: none reason: not-a-software-company detail: >- Biosplice is a clinical-stage drug developer whose product is an injectable small molecule, not software; www.biosplice.com is a 13KB ASP.NET brochure site with no robots.txt and no sitemap.xml, every spec and /.well-known/ path is rewritten to the CMS 404 page, and api./developer./docs./portal./status./graphql./mcp.biosplice.com have no DNS record at all. evidence: - url: https://www.biosplice.com/openapi.json status: 404 - url: https://www.biosplice.com/.well-known/agent-card.json status: 404 - url: https://www.biosplice.com/.well-known/agent.json status: 404 - url: https://www.biosplice.com/llms.txt status: 404 - url: https://www.biosplice.com/sitemap.xml status: 404 - url: https://api.github.com/orgs/biosplice status: 404 checked: '2026-08-07'