aid: boltz
name: Boltz
description: >-
  Boltz (Boltz PBC) is a public-benefit AI research company building open-source
  and proprietary foundation models for biomolecular structure prediction,
  binding-affinity estimation, and generative protein and small-molecule design.
  Its open-source models (Boltz-1, Boltz-2, BoltzGen, all MIT-licensed) are used
  by 100,000+ scientists across pharma and biotech, and its commercial platform,
  Boltz Lab, pairs those models with managed compute and collaborative interfaces.
  The Boltz Compute API exposes these capabilities as asynchronous jobs -
  structure & binding prediction, ADME prediction, and small-molecule / protein
  design and library screening - with official Python, TypeScript, and Go SDKs, a
  CLI, and an MCP server for agentic drug-discovery workflows. Backed by a $28M
  seed round led by Amplify Partners, a16z, and Zetta Venture Partners.
url: https://raw.githubusercontent.com/api-evangelist/boltz/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- amplify-partners
x-tier: enriched
x-tier-reason: portfolio-lead
accessModel:
  pricing: unknown
  onboarding: self-serve
  trial: false
  try_now: false
  public: false
  label: Self-serve signup
  confidence: medium
  source:
  - authentication
  generated: '2026-07-22'
  method: derived
image: https://boltz.bio/android-chrome-512x512.png
specificationVersion: '0.20'
created: '2026-07-17'
modified: '2026-07-18'
tags:
- Company
- Digital Biology
- Drug Discovery
- Artificial Intelligence
- Machine Learning
- Protein Design
- Structure Prediction
- Life Sciences
- Compute
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
apis:
- aid: boltz:boltz-admin-api
  name: Boltz Admin API
  description: The Admin API from Boltz — 7 operation(s) for admin.
  humanURL: https://api.boltz.bio/docs
  baseURL: https://api.boltz.bio
  tags:
  - Admin
  properties:
  - type: OpenAPI
    url: openapi/boltz-admin-api-openapi.yml
  - type: APIReference
    url: https://api.boltz.bio/docs
  - type: Documentation
    url: https://docs.boltz.bio
  - type: Authentication
    url: authentication/boltz-authentication.yml
- aid: boltz:boltz-auth-api
  name: Boltz Auth API
  description: The Auth API from Boltz — 1 operation(s) for auth.
  humanURL: https://api.boltz.bio/docs
  baseURL: https://api.boltz.bio
  tags:
  - Auth
  properties:
  - type: OpenAPI
    url: openapi/boltz-auth-api-openapi.yml
  - type: APIReference
    url: https://api.boltz.bio/docs
  - type: Documentation
    url: https://docs.boltz.bio
  - type: Authentication
    url: authentication/boltz-authentication.yml
- aid: boltz:boltz-cli-api
  name: Boltz CLI API
  description: The CLI API from Boltz — 1 operation(s) for cli.
  humanURL: https://api.boltz.bio/docs
  baseURL: https://api.boltz.bio
  tags:
  - CLI
  properties:
  - type: OpenAPI
    url: openapi/boltz-cli-api-openapi.yml
  - type: APIReference
    url: https://api.boltz.bio/docs
  - type: Documentation
    url: https://docs.boltz.bio
  - type: Authentication
    url: authentication/boltz-authentication.yml
- aid: boltz:boltz-predictions-api
  name: Boltz Predictions API
  description: The Predictions API from Boltz — 8 operation(s) for predictions.
  humanURL: https://api.boltz.bio/docs
  baseURL: https://api.boltz.bio
  tags:
  - Predictions
  properties:
  - type: OpenAPI
    url: openapi/boltz-predictions-api-openapi.yml
  - type: APIReference
    url: https://api.boltz.bio/docs
  - type: Documentation
    url: https://docs.boltz.bio
  - type: Authentication
    url: authentication/boltz-authentication.yml
- aid: boltz:boltz-protein-api
  name: Boltz Protein API
  description: The Protein API from Boltz — 15 operation(s) for protein.
  humanURL: https://api.boltz.bio/docs
  baseURL: https://api.boltz.bio
  tags:
  - Protein
  properties:
  - type: OpenAPI
    url: openapi/boltz-protein-api-openapi.yml
  - type: APIReference
    url: https://api.boltz.bio/docs
  - type: Documentation
    url: https://docs.boltz.bio
  - type: Authentication
    url: authentication/boltz-authentication.yml
- aid: boltz:boltz-share-links-api
  name: Boltz Share Links API
  description: The Share Links API from Boltz — 4 operation(s) for share links.
  humanURL: https://api.boltz.bio/docs
  baseURL: https://api.boltz.bio
  tags:
  - Share Links
  properties:
  - type: OpenAPI
    url: openapi/boltz-share-links-api-openapi.yml
  - type: APIReference
    url: https://api.boltz.bio/docs
  - type: Documentation
    url: https://docs.boltz.bio
  - type: Authentication
    url: authentication/boltz-authentication.yml
- aid: boltz:boltz-small-molecule-api
  name: Boltz Small Molecule API
  description: The Small Molecule API from Boltz — 14 operation(s) for small molecule.
  humanURL: https://api.boltz.bio/docs
  baseURL: https://api.boltz.bio
  tags:
  - Small Molecule
  properties:
  - type: OpenAPI
    url: openapi/boltz-small-molecule-api-openapi.yml
  - type: APIReference
    url: https://api.boltz.bio/docs
  - type: Documentation
    url: https://docs.boltz.bio
  - type: Authentication
    url: authentication/boltz-authentication.yml
common:
- type: Website
  url: https://boltz.bio
- type: DeveloperPortal
  url: https://docs.boltz.bio
- type: Documentation
  url: https://docs.boltz.bio
- type: APIReference
  url: https://api.boltz.bio/docs
- type: GettingStarted
  url: https://docs.boltz.bio/user-guide/introduction/Quickstart.md
- type: OpenAPI
  url: openapi/boltz-compute.yml
- type: Authentication
  url: authentication/boltz-authentication.yml
- type: Packages
  url: packages/boltz-packages.yml
- type: SDKs
  url: packages/boltz-packages.yml
- type: CLI
  url: cli/boltz-cli.yml
- type: MCPServer
  url: mcp/boltz-mcp.yml
- type: AgentSkill
  url: skills/_index.yml
- type: LLMsTxt
  url: llms/boltz-llms.txt
- type: Conventions
  url: conventions/boltz-conventions.yml
- type: DataModel
  url: data-model/boltz-data-model.yml
- type: ErrorCatalog
  url: errors/boltz-problem-types.yml
- type: Conformance
  url: conformance/boltz-conformance.yml
- type: Lifecycle
  url: lifecycle/boltz-lifecycle.yml
- type: StatusPage
  url: https://status.boltz.bio
- type: ChangeLog
  url: changelog/boltz-changelog.yml
- type: Sandbox
  url: sandbox/boltz-sandbox.yml
- type: DomainSecurity
  url: security/boltz-domain-security.yml
- type: Pricing
  url: https://boltz.bio/pricing
- type: Blog
  url: https://boltz.bio/news
- type: GitHubOrganization
  url: https://github.com/boltz-bio
- type: SignUp
  url: https://lab.boltz.bio
- type: Support
  url: https://boltz.bio/join-slack
- type: TermsOfService
  url: https://docs.boltz.bio/terms-of-service/terms-of-service.md
- type: PrivacyPolicy
  url: https://docs.boltz.bio/privacy-policy/privacy-policy.md
x-enrichment:
  date: '2026-07-19'
  status: backfilled
  pass: local-v1
  note: backfilled from .gitignore signal + verified work evidence