generated: '2026-07-18'
method: searched
source: https://github.com/boltz-bio/boltz-api-skills (skills-python/, plugins/)
description: >-
  Official Boltz Agent Skills, published in the boltz-bio/boltz-api-skills
  repository as Claude Code / Codex skills and plugins for the Boltz Compute API.
  Each skill wraps one marquee compute workflow. Saved as an index (verbatim
  skills live in the provider repo); grounded in real Boltz API operations.
repo: https://github.com/boltz-bio/boltz-api-skills
plugins:
  - boltz          # model + API workflows
  - boltz-mcpb     # MCP bundle plugin (see mcp/boltz-mcp.yml)
  - boltz-api-cli  # CLI plugin (see cli/boltz-cli.yml)
skills:
  - name: boltz-structure-and-binding
    description: Predict 3D structure and binding affinity for a biomolecular complex.
    api: Boltz Compute API
    operations:
      - predictionsStructureAndBindingEstimateCost
      - predictionsStructureAndBindingStart
      - predictionsStructureAndBindingGet
  - name: boltz-small-molecule-design
    description: Run de-novo small-molecule design against a protein target.
    api: Boltz Compute API
    operations:
      - smallMoleculeDesignEstimateCost
      - smallMoleculeDesignStart
      - smallMoleculeDesignListResults
      - smallMoleculeDesignStop
  - name: boltz-small-molecule-screen
    description: Screen a small-molecule library against a target.
    api: Boltz Compute API
    operations:
      - smallMoleculeLibraryScreenEstimateCost
      - smallMoleculeLibraryScreenStart
      - smallMoleculeLibraryScreenListResults
  - name: boltz-protein-design
    description: Design protein / peptide binders against a target with BoltzGen.
    api: Boltz Compute API
    operations:
      - proteinDesignListCuratedSpecifications
      - proteinDesignEstimateCost
      - proteinDesignStart
      - proteinDesignListResults
  - name: boltz-protein-screen
    description: Screen a protein / binder library against a target.
    api: Boltz Compute API
    operations:
      - proteinLibraryScreenEstimateCost
      - proteinLibraryScreenStart
      - proteinLibraryScreenListResults
  - name: boltz-check-status
    description: Check job progress and the authenticated identity before running work.
    api: Boltz Compute API
    operations:
      - authMe
      - cliVersion