# Bota Biosciences

> Bota Biosciences (Bota Bio, 恩和科技) is an industrial and synthetic biology company that applies AI-driven computation and laboratory automation to bio-manufacturing. Its Bota Biofoundry and Cell2Cloud platforms pair computational algorithms with non-model industrial strain engineering, rapid iterative enzyme engineering and performance protein design, and it sells the output as physical ingredients — bio-preservatives, biomimetic proteins and personal-care actives — through its HeliaGenesis and YuccaElements brands.

Generated by the API Evangelist enrichment pipeline on 2026-08-08 from the company's public website. The provider does not publish an llms.txt of its own (https://bota.bio/llms.txt returned 404 on 2026-08-08).

**No public API.** As of 2026-08-08 Bota Biosciences publishes no developer portal, no API documentation, no SDKs, no OpenAPI/AsyncAPI/GraphQL contract, no MCP server and no A2A agent card. There is no GitHub organization. Its computational software is internal laboratory tooling, and its SAION AI platform is a login-gated application with an administrator-managed account whitelist — there is no self-serve developer access and no published reference. Do not attempt to call a Bota Biosciences API; none is offered to developers.

## Company

- [Bota Biosciences](https://bota.bio/): Company homepage, in English and Chinese.
- [About Bota](https://bota.bio/about-bota/): Vision, mission and core values. CEO: Dr. Cheryl Cui. CTO: Yi-Shu Tai. Founded 2019, with operations in Hangzhou, China and the San Francisco Bay Area.
- [Contact](https://bota.bio/contact/): Contact form for business, partnership and media enquiries.
- [News](https://bota.bio/bota-news/): Dated company news and press releases. RSS at https://bota.bio/feed/.
- [LinkedIn](https://www.linkedin.com/company/botabio)

## Technology

- [Bota Biofoundry](https://bota.bio/bota-biofoundry/): The in-house biofoundry platform combining computer algorithms with laboratory biotechnology to accelerate design-build-test-learn cycles.
- [Computational Biology](https://bota.bio/computational-biology/): Self-developed software covering experimental design, instrument automation, high-throughput sequencing, protein prediction and research assistants. Internal tooling — not offered as a product or API.
- [Non-Model Industrial Strain Engineering](https://bota.bio/non-model-industrial-strain-engineering/): Strain and process optimization for nutrition and food biopreservative production from cane sugar or glucose.
- [Rapid Iterative Enzyme Engineering](https://bota.bio/rapid-iterative-enzyme-engineering/): Bio-catalysis replacing conventional chemical routes to improve yield and reduce impurities and pollution.
- [Performance Protein Solutions](https://bota.bio/performance-protein-solutions/): Protein and peptide platform behind the Prorylia biomimetic protein line.

## Products and brands

- [HeliaGenesis](https://www.heliagenesis.com/): Food and nutrition brand — Purtect bio-preservatives (nisin, natamycin, ε-poly-lysine and ε-poly-lysine HCl, lysozyme) and nutritional ingredients.
- [YuccaElements](https://www.yuccaelements.com/): Personal care brand — synthetic biological materials for global personal care formulation.
- Prorylia FN Fibronectin: biomimetic protein for personal care.
- Re² Coffea Arabica Endorphins: upcycled coffee-derived peptide, expanded globally with Syensqo.

## SAION AI

- [SAION AI launch announcement](https://bota.bio/bota-launches-saion-ai-physical-ai-platform-for-biomanufacturing/): Announced 2026-03-16. A three-layer "Physical AI" platform — Cognition (multi-scale biological understanding over the Cell2Cloud Biofoundry data), Orchestration (an LLM-driven agent harness coordinating multi-agent collaboration across 316 specialized scientific tools) and Execution (a proprietary Biological Protocol Language that drives laboratory hardware).
- [saion.ai](https://saion.ai/): The application itself. A Flutter/CanvasKit single-page app that renders entirely to a WebGL canvas, so the served HTML contains no readable content. Access is behind a login and an administrator-managed email/domain whitelist. No public API, no developer documentation and no signup for programmatic access are published.
- Agent-facing note: saion.ai/robots.txt carries a Cloudflare content-signals policy of `search=yes, ai-train=no, use=reference` and explicitly disallows ClaudeBot, GPTBot, CCBot, Google-Extended, Bytespider, Amazonbot, Applebot-Extended and meta-externalagent. `User-agent: *` is `Allow: /`.

## Partnerships

- [BASF — bio-identical Collagen III](https://bota.bio/bota-biosciences-and-basf-introduce-bio-identical-collagen-iii-powered-by-ai/)
- [Syensqo — Re² Coffea Arabica peptide, global personal care](https://bota.bio/bota-biosciences-and-syensqo-expand-re2-coffea-arabica-peptide-to-global-personal-care-market/)
- [Proya — first strategic move into synthetic biology](https://bota.bio/proya-partners-with-bota-bio-in-its-first-strategic-move-into-synthetic-biology/)
- [SynBioBeta delegation visit](https://bota.bio/synbiobeta-delegation-visits-bota-to-explore-physical-ai-powered-biomanufacturing/)

## Optional

- [API Evangelist profile](https://apis.io/provider/bota-biosciences/): This company's entry in the APIs.io catalog.
- [Hiive secondary-market listing](https://www.hiive.com/securities/bota-biosciences-stock): Private-market share listing that surfaced this company into the harvest backlog.