{
  "meta": {
    "limit": 20,
    "next": "/chembl/api/data/activity?limit=20&offset=20",
    "offset": 0,
    "previous": null,
    "total_count": 24527044
  },
  "activities": [
    {
      "activity_id": 31863,
      "assay_chembl_id": "CHEMBL1909072",
      "assay_description": "Inhibitory concentration of the compound required to inhibit 50% of COX-2 activity in human recombinant enzyme",
      "assay_type": "B",
      "bao_endpoint": "BAO_0000190",
      "bao_format": "BAO_0000019",
      "bao_label": "IC50",
      "canonical_smiles": "CC(=O)Oc1ccccc1C(=O)O",
      "data_validity_comment": null,
      "document_chembl_id": "CHEMBL1124375",
      "document_journal": "J. Med. Chem.",
      "document_year": 1999,
      "molecule_chembl_id": "CHEMBL25",
      "pchembl_value": 4.22,
      "relation": "=",
      "standard_flag": true,
      "standard_relation": "=",
      "standard_text_value": null,
      "standard_type": "IC50",
      "standard_units": "nM",
      "standard_value": 60000,
      "target_chembl_id": "CHEMBL301",
      "target_organism": "Homo sapiens",
      "target_pref_name": "Cyclooxygenase-2",
      "target_tax_id": "9606",
      "type": "IC50",
      "units": "uM",
      "value": "60"
    },
    {
      "activity_id": 44819,
      "assay_chembl_id": "CHEMBL1614249",
      "assay_description": "Inhibition of human EGFR kinase activity using ATP as substrate",
      "assay_type": "B",
      "bao_endpoint": "BAO_0000190",
      "bao_format": "BAO_0000019",
      "bao_label": "IC50",
      "canonical_smiles": "CN1C=NC2=C1C(=O)N(C(=O)N2C)C",
      "data_validity_comment": null,
      "document_chembl_id": "CHEMBL1088438",
      "document_journal": "Eur. J. Med. Chem.",
      "document_year": 2005,
      "molecule_chembl_id": "CHEMBL113",
      "pchembl_value": 7.40,
      "relation": "=",
      "standard_flag": true,
      "standard_relation": "=",
      "standard_text_value": null,
      "standard_type": "IC50",
      "standard_units": "nM",
      "standard_value": 40,
      "target_chembl_id": "CHEMBL203",
      "target_organism": "Homo sapiens",
      "target_pref_name": "Epidermal growth factor receptor erbB1",
      "target_tax_id": "9606",
      "type": "IC50",
      "units": "nM",
      "value": "40"
    }
  ]
}