aid: circle-pharma
name: Circle Pharma
description: >-
  Circle Pharma is a clinical-stage biopharmaceutical company in South San Francisco, California,
  developing cell-permeable, orally bioavailable macrocycle therapies for cancer. Founded in 2013 by
  Matthew P. Jacobson and Scott Lokey out of work on predicting synthetic macrocycle cell permeability,
  the company applies its proprietary MXMO structure-based design platform to protein-protein
  interactions that conventional small molecules cannot reach. Its pipeline targets cyclins, the
  regulators of the cell cycle that drive many cancers: lead program CID-078, a first-in-class oral
  cyclin A/B RxL inhibitor, is in Phase 1 for advanced solid tumors, followed by a preclinical cyclin
  D1 RxL inhibitor and undisclosed cyclin programs partnered with Boehringer Ingelheim. Circle Pharma
  closed a $90M Series D led by The Column Group in 2024 and has an agreement with Eli Lilly to use
  Lilly TuneLab to strengthen the AI/ML side of the MXMO platform. Circle Pharma runs no developer
  program and publishes no product API; the only machine-readable surface it exposes is the
  anonymously readable WordPress REST content API behind circlepharma.com.
image: https://circlepharma.com/wp-content/uploads/2024/01/Asset-2@2x.png
url: https://raw.githubusercontent.com/api-evangelist/circle-pharma/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.20'
created: '2026-08-01'
modified: '2026-08-01'
tags:
- Company
- biotechnology
- pharmaceuticals
- oncology
- drug-discovery
- macrocycles
- clinical-trials
- life-sciences
- content-api
apis:
- aid: circle-pharma:circle-pharma-content-api
  name: Circle Pharma Content API
  description: >-
    The anonymously readable WordPress REST API behind circlepharma.com. It exposes Circle Pharma
    press releases, publications and in-the-news items (posts), site pages, the media library, the
    leadership and board roster (team + member_type taxonomy), the events calendar (all_events +
    event_type taxonomy) and cross-content search. This is not a developer product Circle Pharma
    markets; it is the site's own discovery surface, published at /wp-json/ and verified to return
    data without credentials. The OpenAPI in this repo is derived from that published route index.
  humanURL: https://developer.wordpress.org/rest-api/
  baseURL: https://circlepharma.com/wp-json
  tags:
  - content
  - press-releases
  - events
  - wordpress
  properties:
  - type: OpenAPI
    url: openapi/circle-pharma-content-openapi.yml
  - type: Overlay
    url: overlays/circle-pharma-content-overlay.yaml
  - type: Authentication
    url: authentication/circle-pharma-authentication.yml
  - type: ErrorCatalog
    url: errors/circle-pharma-problem-types.yml
  - type: Conventions
    url: conventions/circle-pharma-conventions.yml
  - type: DataModel
    url: data-model/circle-pharma-data-model.yml
  x-contract-provenance: >-
    Derived by the API Evangelist enrichment pipeline from the WordPress REST route index the site
    publishes at https://circlepharma.com/wp-json/ and verified against live anonymous responses on
    2026-08-01. Circle Pharma publishes no developer documentation, no API reference and no support
    channel for this surface, so no Documentation/APIReference/GettingStarted pointers are emitted —
    the humanURL above is the upstream WordPress REST handbook that describes the wp/v2 contract.
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://circlepharma.com/
- type: About
  url: https://circlepharma.com/about-us
- type: Blog
  url: https://circlepharma.com/whats-new
- type: BlogRSS
  url: https://circlepharma.com/feed/
- type: PressReleases
  url: https://circlepharma.com/press-releases
- type: Publications
  url: https://circlepharma.com/publications
- type: Events
  url: https://circlepharma.com/upcoming-events
- type: Careers
  url: https://circlepharma.com/work-with-us
- type: Contact
  url: https://circlepharma.com/contact-us
- type: Investors
  url: https://circlepharma.com/investors
- type: Support
  url: https://circlepharma.com/contact-us
- type: TermsOfService
  url: https://circlepharma.com/terms-of-use
- type: PrivacyPolicy
  url: https://circlepharma.com/privacy-policy
- type: LinkedIn
  url: https://www.linkedin.com/company/circle-pharma-inc-/
- type: SecondaryMarket
  url: https://forgeglobal.com/circle-pharma_stock/
- type: Authentication
  url: authentication/circle-pharma-authentication.yml
- type: Conventions
  url: conventions/circle-pharma-conventions.yml
- type: Conformance
  url: conformance/circle-pharma-conformance.yml
- type: ErrorCatalog
  url: errors/circle-pharma-problem-types.yml
- type: Lifecycle
  url: lifecycle/circle-pharma-lifecycle.yml
- type: DataModel
  url: data-model/circle-pharma-data-model.yml
- type: WellKnown
  url: well-known/circle-pharma-well-known.yml
- type: DomainSecurity
  url: security/circle-pharma-domain-security.yml
- type: LLMsTxt
  url: llms/circle-pharma-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-01'
  status: enriched
  artifacts_added: 15
  pass: local-v1