aid: cirius-therapeutics
name: Cirius Therapeutics
description: 'Cirius Therapeutics, Inc. is a privately held clinical-stage pharmaceutical
  company based in Grand Rapids, Michigan, developing oral therapies for chronic metabolic
  diseases driven by insulin resistance, including Type 2 Diabetes, Type 1 Diabetes,
  obesity and gestational diabetes. Its lead candidate, azemiglitazone (CIR-0602K /
  MSDC-0602K), is a next-generation insulin sensitizer that inhibits the mitochondrial
  pyruvate carrier (MPC) to re-balance mitochondrial metabolism, improve glycemic control,
  preserve lean muscle mass and shift visceral fat to subcutaneous and brown adipose
  tissue, including in combination with GLP-1 receptor agonists such as tirzepatide.
  The company publishes a corporate marketing website only; it operates no developer
  program, public API, or machine-readable API contract.'
url: https://raw.githubusercontent.com/api-evangelist/cirius-therapeutics/refs/heads/main/apis.yml
image: https://img1.wsimg.com/isteam/ip/40701c08-78b4-429c-9131-4a2e35286e89/Cirius_1420x1200_Full-baa8525.jpg
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.23'
created: '2026-08-09'
modified: '2026-08-09'
tags:
- Company
- Pharmaceuticals
- Biotechnology
- Life Sciences
- Healthcare
- Clinical Trials
- Metabolic Disease
- Diabetes
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/cirius-therapeutics-domain-security.yml
- type: LLMsTxt
  url: llms/cirius-therapeutics-llms.txt
- type: Website
  url: https://ciriustx.com/
- type: News
  url: https://ciriustx.com/news
- type: Contact
  url: https://ciriustx.com/contact
- type: Team
  url: https://ciriustx.com/team
- type: Science
  url: https://ciriustx.com/science
- type: SecondaryMarket
  url: https://forgeglobal.com/cirius-therapeutics_stock/
x-enrichment:
  date: '2026-08-09'
  status: minimal
  artifacts_added: 2
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: Cirius Therapeutics is a clinical-stage pharmaceutical company whose entire
    web presence is a five-page GoDaddy-built marketing site (Home/Team/Science/News/Contact)
    about the MPC inhibitor azemiglitazone — there is no developer section, no API host,
    no GitHub organization, and every contract-discovery path on ciriustx.com returned
    a hard 404.
  evidence:
  - url: https://ciriustx.com/
    status: 200
  - url: https://ciriustx.com/llms.txt
    status: 200
  - url: https://ciriustx.com/openapi.json
    status: 404
  - url: https://ciriustx.com/.well-known/agent-card.json
    status: 404
  - url: https://ciriustx.com/.well-known/security.txt
    status: 404
  - url: https://api.github.com/orgs/cirius-therapeutics
    status: 404
  checked: '2026-08-09'