# City Therapeutics

> City Therapeutics, Inc. is a privately held, clinical-stage biotechnology company in Kendall Square, Cambridge, Massachusetts, founded in 2024 by pioneers of RNA interference. It engineers next-generation RNAi trigger molecules — including proprietary cleavage-inducing tiny ("city") RNAs — paired with precision targeting ligands that deliver siRNAs beyond the liver into ocular, CNS and other extrahepatic tissues. City Therapeutics does not operate a public API, developer program, or machine-readable interface.

This file was generated by the API Evangelist enrichment pipeline from City Therapeutics' public corporate website (https://www.citytx.com/). The company publishes no /llms.txt of its own (probed 2026-08-02, HTTP 404). method: generated.

## APIs

City Therapeutics publishes no public API. Probes on 2026-08-02 of the corporate host and of the api./developer./docs. subdomains returned no OpenAPI, Swagger, GraphQL, AsyncAPI, MCP, or A2A surface. There is no developer portal, SDK, or documentation site.

## Programs

- [CITY-FXI](https://www.citytx.com/home#factor-xi): RNAi therapeutic candidate targeting coagulation Factor XI for thromboembolic disease; hepatic delivery.
- [CITY-RBP4](https://www.citytx.com/home#rbp4): RNAi therapeutic candidate reducing RBP4 expression for Stargardt disease and geographic atrophy; hepatic delivery.
- [Pipeline & programs](https://www.citytx.com/home#pipeline): Additional undisclosed hepatic, ocular and CNS programs in discovery and IND/CTA-enabling stages.

## Company

- [Website](https://www.citytx.com/)
- [Our approach](https://www.citytx.com/home#Approach)
- [Leadership, board and founders](https://www.citytx.com/home#team)
- [Culture & careers](https://www.citytx.com/home#culture)
- [Careers (Greenhouse)](https://boards.greenhouse.io/citytherapeutics)
- [News](https://www.citytx.com/news)
- [News RSS](https://www.citytx.com/news?format=rss)
- [Contact](https://www.citytx.com/home#contact)
- [LinkedIn](https://www.linkedin.com/company/city-therapeutics/)
- [X](https://x.com/CityTx_)

## Legal

- [Terms of use](https://www.citytx.com/terms-of-use)
- [Privacy policy](https://www.citytx.com/privacy-policy)
- [Cookie policy](https://www.citytx.com/cookie-policy)
- [HCP privacy notice (UK)](https://www.citytx.com/hcp-privacy-notice-uk)
- [Clinical trial participant privacy notice](https://www.citytx.com/clinical-trial-participant-privacy-notice)

## Repo artifacts

- [Domain security probe](security/city-therapeutics-domain-security.yml)
- [Well-known discovery probe (all 404 — negative evidence)](well-known/city-therapeutics-well-known.yml)