# Cullgen

> Cullgen Inc. is a clinical-stage biopharmaceutical company in San Diego, California, developing
> first-in-class targeted protein degradation medicines on its uSMITE (ubiquitin-mediated, small
> molecule-induced target elimination) platform and its degrader-antibody conjugate (DAC) chemistry.
> Gyre Therapeutics completed an all-stock acquisition of Cullgen on 4 May 2026.

This file was generated by API Evangelist from the public Cullgen web surface. Cullgen does not publish
an llms.txt of its own (https://www.cullgen.com/llms.txt returned HTTP 404 on 2026-08-04).

## API surface

Cullgen publishes **no public API**. Probes on 2026-08-04 against www.cullgen.com found no OpenAPI,
Swagger, GraphQL, AsyncAPI, MCP, or A2A agent-card surface, no developer portal or documentation host
(api., docs., developer., portal. subdomains do not resolve), no GitHub organization, and no packages in
any public registry. Requests for machine-readable contracts should go to inquiries@cullgen.com.

## Company

- [Cullgen](https://www.cullgen.com/): Corporate website.
- [About Us](https://www.cullgen.com/about-us): Company overview and leadership.
- [Protein Degradation](https://www.cullgen.com/protein-degradation): The uSMITE targeted protein degradation platform.
- [Degrader-Antibody Conjugates](https://www.cullgen.com/dacs): DAC science.
- [Pipeline](https://www.cullgen.com/pipeline-1): Development programs.
- [News & Press Releases](https://www.cullgen.com/news-press-releases): Company announcements.
- [Events](https://www.cullgen.com/events): Conference participation.
- [Careers](https://www.cullgen.com/careers-1): Open roles.
- [Contact Us](https://www.cullgen.com/contact-us): inquiries@cullgen.com.
- [Locations](https://www.cullgen.com/locations): Offices.

## Profile

- [apis.yml](https://raw.githubusercontent.com/api-evangelist/cullgen/refs/heads/main/apis.yml): The APIs.json profile for Cullgen.
- [Domain security](https://raw.githubusercontent.com/api-evangelist/cullgen/refs/heads/main/security/cullgen-domain-security.yml): Probed TLS/HSTS/DNSSEC/CAA/SPF/DMARC posture.

## Notes

- Cullgen's robots.txt blocks the major AI crawlers (anthropic-ai, ClaudeBot, GPTBot, CCBot, Google-Extended and others) with `Disallow: /` — the Squarespace default AI-blocking policy.
- No security.txt, trust center, vulnerability disclosure program, or status page was found.