aid: grin-therapeutics name: GRIN Therapeutics description: >- GRIN Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to the research and development of precision therapeutics for pediatric neurodevelopmental disorders caused by NMDA receptor dysfunction. It is an affiliate of Neurvati Neurosciences, a Blackstone Life Sciences portfolio company, and traces its founding to Dr. Pierandrea Muglia's attendance at the 2019 CFERV Conference on GRIN Variants at Emory University. Its lead investigational asset is radiprodil, an orally bioavailable selective negative allosteric modulator of the GluN2B subunit of the NMDA receptor, designed to fine-tune dysregulated receptor activity rather than fully block the channel. Radiprodil is in development for GRIN-related neurodevelopmental disorder (GRIN-NDD) arising from gain-of-function variants in GRIN1, GRIN2A, GRIN2B and GRIN2D, and for tuberous sclerosis complex (TSC) and focal cortical dysplasia (FCD) type II. The clinical programme comprises the completed Phase 1b/2a Honeycomb trial, the enrolling global Phase 3 Beeline registrational trial, the Phase 1b/2a Astroscape trial in TSC and FCD type II, and a GRIN-NDD natural history study; radiprodil carries FDA Breakthrough Therapy, Orphan Drug and Rare Pediatric Disease designations and EMA PRIME and Orphan Drug designations. In May 2025 GRIN Therapeutics entered an exclusive collaboration with Angelini Pharma to develop and commercialise radiprodil outside North America. GRIN Therapeutics runs no developer program and publishes no product API, no developer portal and no API documentation; the only machine-readable surface reachable without credentials is the WordPress REST content API behind grintherapeutics.com, catalogued here. image: https://grintherapeutics.com/wp-content/uploads/2023/11/neurvati_grin_inline_fullcolor_rgb_6in@72ppi.png url: https://raw.githubusercontent.com/api-evangelist/grin-therapeutics/refs/heads/main/apis.yml x-type: company x-source: harvest:secondary-market x-tier: profiled x-tier-reason: enriched specificationVersion: '0.20' created: '2026-08-04' modified: '2026-08-04' tags: - Company - biotechnology - pharmaceuticals - neuroscience - rare-disease - precision-medicine - clinical-trials - pediatrics - epilepsy - life-sciences - content-api apis: - aid: grin-therapeutics:grin-therapeutics-discovery-api name: GRIN Therapeutics Discovery API description: Route, type, taxonomy and status discovery documents. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - discovery properties: - type: OpenAPI url: openapi/grin-therapeutics-discovery-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - aid: grin-therapeutics:grin-therapeutics-media-api name: GRIN Therapeutics Media API description: Media library (174 attachments at harvest time). humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - media properties: - type: OpenAPI url: openapi/grin-therapeutics-media-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - aid: grin-therapeutics:grin-therapeutics-oembed-api name: GRIN Therapeutics Oembed API description: oEmbed 1.0 provider endpoint for grintherapeutics.com URLs. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - oembed properties: - type: OpenAPI url: openapi/grin-therapeutics-oembed-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - aid: grin-therapeutics:grin-therapeutics-pages-api name: GRIN Therapeutics Pages API description: Corporate and clinical-programme pages (10 published at harvest time). humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - pages properties: - type: OpenAPI url: openapi/grin-therapeutics-pages-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - aid: grin-therapeutics:grin-therapeutics-posts-api name: GRIN Therapeutics Posts API description: >- Blog/news post collection. Registered and reachable, but empty (X-WP-Total 0) — the News page is authored as a WPBakery page, not as posts. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - posts properties: - type: OpenAPI url: openapi/grin-therapeutics-posts-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - aid: grin-therapeutics:grin-therapeutics-search-api name: GRIN Therapeutics Search API description: Cross-content search across published objects. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - search properties: - type: OpenAPI url: openapi/grin-therapeutics-search-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - aid: grin-therapeutics:grin-therapeutics-taxonomy-api name: GRIN Therapeutics Taxonomy API description: >- Categories and tags. Registered by WordPress core; every term reports count 0 on this deployment. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - taxonomy properties: - type: OpenAPI url: openapi/grin-therapeutics-taxonomy-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - aid: grin-therapeutics:grin-therapeutics-users-api name: GRIN Therapeutics Users API description: Public author records. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://grintherapeutics.com/wp-json tags: - users properties: - type: OpenAPI url: openapi/grin-therapeutics-users-api-openapi.yml - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml maintainers: - FN: Kin Lane email: kin@apievangelist.com - FN: APIs.json email: info@apis.io common: - type: Overlay url: overlays/grin-therapeutics-content-overlay.yaml - type: Website url: https://grintherapeutics.com/ - type: About url: https://grintherapeutics.com/about-grin-therapeutics/ - type: Science url: https://grintherapeutics.com/our-science/ - type: DiseaseState url: https://grintherapeutics.com/disease-state/ - type: PatientResources url: https://grintherapeutics.com/resources-for-patients-and-caregivers/ - type: News url: https://grintherapeutics.com/news/ - type: BlogRSS url: https://grintherapeutics.com/feed/ - type: Careers url: https://grintherapeutics.com/careers/ - type: Contact url: https://grintherapeutics.com/contact/ - type: Support url: https://grintherapeutics.com/contact/ - type: PrivacyPolicy url: https://grintherapeutics.com/privacy/ - type: CookiePolicy url: https://grintherapeutics.com/cookie-policy/ - type: LinkedIn url: https://www.linkedin.com/company/grin-therapeutics-inc - type: Twitter url: https://twitter.com/GRIN_tx - type: ParentCompany url: https://neurvati.com/ - type: SecondaryMarket url: https://forgeglobal.com/grin-therapeutics_stock/ - type: Authentication url: authentication/grin-therapeutics-authentication.yml - type: Conventions url: conventions/grin-therapeutics-conventions.yml - type: Conformance url: conformance/grin-therapeutics-conformance.yml - type: ErrorCatalog url: errors/grin-therapeutics-problem-types.yml - type: Lifecycle url: lifecycle/grin-therapeutics-lifecycle.yml - type: DataModel url: data-model/grin-therapeutics-data-model.yml - type: WellKnown url: well-known/grin-therapeutics-well-known.yml - type: DomainSecurity url: security/grin-therapeutics-domain-security.yml - type: LLMsTxt url: llms/grin-therapeutics-llms.txt - type: AgentSkill url: skills/_index.yml x-enrichment: date: '2026-08-04' status: enriched artifacts_added: 15 pass: local-v1