aid: iecure name: iECURE description: >- iECURE is a clinical-stage genetic medicines company developing variant-agnostic, in vivo targeted gene insertion therapies for rare, life-threatening inherited metabolic diseases, with an initial focus on urea cycle disorders and other neurometabolic conditions of the liver. The company takes its name from iecur, the Latin word for liver, and was founded on the translational gene therapy research of James M. Wilson, M.D., Ph.D., advancing its pipeline in partnership with the University of Pennsylvania Gene Therapy Program. Its lead candidate, ECUR-506, pairs a dual-AAV delivery approach with Precision BioSciences' ARCUS nuclease to insert a functional copy of the OTC gene into the genome of infants with neonatal-onset ornithine transcarbamylase deficiency; it is in the OTC-HOPE study and has received FDA Orphan Drug, Rare Pediatric Disease, Fast Track and RMAT designations plus EU orphan designation, with clinical trial clearances in the United States, United Kingdom, Australia and the EU. Discovery-stage programs target citrullinemia type 1 and phenylketonuria. iECURE has raised roughly $115 million across a $50 million Series A in 2021 and a $65 million Series A-1 in 2022 from Versant Ventures, OrbiMed, Novo Holdings, the Qatar Investment Authority, LYFE Capital and Double Point Ventures. iECURE runs no developer program and publishes no product API, developer portal or API documentation. The only machine-readable surface reachable without credentials is the WordPress REST content API behind iecure.com, catalogued here. image: https://iecure.com/wp-content/uploads/iECURE_White_Logo.png url: https://raw.githubusercontent.com/api-evangelist/iecure/refs/heads/main/apis.yml x-type: company x-source: harvest:secondary-market x-tier: profiled x-tier-reason: enriched specificationVersion: '0.23' created: '2026-08-22' modified: '2026-08-22' tags: - Company - Biotechnology - Genetic Medicine - Gene Editing - Gene Therapy - Rare Disease - Clinical Trials - Life Sciences - Pharmaceuticals - content-api tags_raw: - Company - biotechnology - genetic-medicine - gene-editing - gene-therapy - rare-disease - clinical-trials - life-sciences - pharmaceuticals - content-api apis: - aid: iecure:iecure-discovery-api name: iECURE Discovery API description: >- Route, content-type, taxonomy and status discovery documents for the iECURE WordPress REST deployment. Ten namespaces and 351 routes are registered; only these discovery documents and the content collections below answer without credentials. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://iecure.com/wp-json tags: - Discovery tags_raw: - discovery properties: - type: OpenAPI url: openapi/iecure-discovery-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-posts-api name: iECURE Posts API description: >- The iECURE news archive - press releases, media coverage, awards and scientific publications/presentations. 60 published posts at harvest time across six categories. humanURL: https://iecure.com/news/ baseURL: https://iecure.com/wp-json tags: - Posts tags_raw: - posts properties: - type: OpenAPI url: openapi/iecure-posts-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-pages-api name: iECURE Pages API description: >- Corporate pages - About, Approach, Programs, Careers, Contact, News, Terms of Service, Privacy Notice, Cookie Notice, Expanded Access Policy, Social Media Community Guidelines and Pharmacy Training. 14 published pages at harvest time. humanURL: https://iecure.com/about/ baseURL: https://iecure.com/wp-json tags: - Pages tags_raw: - pages properties: - type: OpenAPI url: openapi/iecure-pages-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-media-api name: iECURE Media API description: >- The media library backing the site - 226 attachments at harvest time, including the corporate logo, pipeline artwork and leadership headshots. humanURL: https://developer.wordpress.org/rest-api/reference/media/ baseURL: https://iecure.com/wp-json tags: - Media tags_raw: - media properties: - type: OpenAPI url: openapi/iecure-media-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-taxonomy-api name: iECURE Taxonomy API description: >- Categories and tags. Six news categories are registered (news, press release, in the news, awards, pubs & pres, Uncategorized); the post_tag taxonomy is registered but empty. humanURL: https://developer.wordpress.org/rest-api/reference/categories/ baseURL: https://iecure.com/wp-json tags: - Taxonomy tags_raw: - taxonomy properties: - type: OpenAPI url: openapi/iecure-taxonomy-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-team-api name: iECURE Team API description: >- The `portfolio` custom post type as deployed by iECURE, which carries team members rather than portfolio work - 35 items at harvest time, classified by the portfolio_entries taxonomy into Leadership, BOD, Advisors, Team and TeamMembers. humanURL: https://iecure.com/about/ baseURL: https://iecure.com/wp-json tags: - Team tags_raw: - team properties: - type: OpenAPI url: openapi/iecure-team-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-search-api name: iECURE Search API description: >- Cross-content search across every published object on iecure.com. 64 objects were addressable at harvest time. humanURL: https://developer.wordpress.org/rest-api/reference/search-results/ baseURL: https://iecure.com/wp-json tags: - Search tags_raw: - search properties: - type: OpenAPI url: openapi/iecure-search-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-users-api name: iECURE Authors API description: >- Author directory. Anonymously readable on this deployment - unusually, since most WordPress sites gate it - returning the two accounts that have published content. humanURL: https://developer.wordpress.org/rest-api/reference/users/ baseURL: https://iecure.com/wp-json tags: - Authors tags_raw: - authors properties: - type: OpenAPI url: openapi/iecure-users-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-comments-api name: iECURE Comments API description: >- Comment collection. Registered and anonymously reachable, but empty - no post on this deployment carries comments. humanURL: https://developer.wordpress.org/rest-api/reference/comments/ baseURL: https://iecure.com/wp-json tags: - Comments tags_raw: - comments properties: - type: OpenAPI url: openapi/iecure-comments-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml - aid: iecure:iecure-oembed-api name: iECURE oEmbed API description: oEmbed 1.0 provider endpoint for iecure.com URLs, returning JSON or XML rich/link responses. humanURL: https://oembed.com/ baseURL: https://iecure.com/wp-json tags: - oEmbed tags_raw: - oembed properties: - type: OpenAPI url: openapi/iecure-oembed-api-openapi.yml - type: Authentication url: authentication/iecure-authentication.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Conventions url: conventions/iecure-conventions.yml - type: DataModel url: data-model/iecure-data-model.yml maintainers: - FN: Kin Lane email: kin@apievangelist.com - FN: APIs.json email: info@apis.io common: - type: Website url: https://iecure.com/ - type: About url: https://iecure.com/about/ - type: Approach url: https://iecure.com/approach/ - type: Pipeline url: https://iecure.com/programs/ - type: News url: https://iecure.com/news/ - type: BlogRSS url: https://iecure.com/feed/ - type: Careers url: https://iecure.com/careers/ - type: Support url: https://iecure.com/contact/ - type: ExpandedAccessPolicy url: https://iecure.com/expanded-access-policy/ - type: PatientResources url: https://otc-hope.com/ - type: TermsOfService url: https://iecure.com/terms-of-service/ - type: PrivacyPolicy url: https://iecure.com/privacy-notice/ - type: CookieNotice url: https://iecure.com/cookie-notice/ - type: SocialMediaGuidelines url: https://iecure.com/social-media-community-guidelines/ - type: LinkedIn url: https://www.linkedin.com/company/iecure - type: SecondaryMarket url: https://www.nasdaqprivatemarket.com/ - type: Authentication url: authentication/iecure-authentication.yml - type: Conventions url: conventions/iecure-conventions.yml - type: Conformance url: conformance/iecure-conformance.yml - type: ErrorCatalog url: errors/iecure-problem-types.yml - type: Lifecycle url: lifecycle/iecure-lifecycle.yml - type: DataModel url: data-model/iecure-data-model.yml - type: DomainSecurity url: security/iecure-domain-security.yml - type: Overlay url: overlays/iecure-content-overlay.yaml - type: LLMsTxt url: llms/iecure-llms.txt - type: RateLimits url: rate-limits/iecure-rate-limits.yml - type: Plans url: plans/iecure-plans-pricing.yml - type: AgentSkill url: skills/_index.yml x-enrichment: date: '2026-08-22' status: enriched artifacts_added: 27 pass: local-v1