aid: kartos-therapeutics name: Kartos Therapeutics description: >- Kartos Therapeutics, Inc. is a privately held, clinical-stage biopharmaceutical company headquartered at 275 Shoreline Drive, Redwood City, California, developing navtemadlin (KRT-232), an orally administered, potent and selective small-molecule inhibitor of MDM2. The company was founded in 2016 by Wayne Rothbaum, president of Quogue Capital and co-founder of Acerta Pharma, around an MDM2 inhibitor in-licensed from Amgen. Navtemadlin blocks the MDM2 protein that suppresses p53, restoring p53 function in tumours that retain wild-type TP53 and driving cell-cycle arrest through p21 and apoptosis through pro-apoptotic Bcl-2 family proteins. The clinical programme is centred on myelofibrosis and includes the enrolling global Phase 3 POIESIS trial of navtemadlin added to ruxolitinib (NCT06479135), the Phase 1b/2 KRT-232-109 combination study (NCT04485260), and the completed Phase 3 BOREAS study of navtemadlin versus best available therapy in JAK-inhibitor relapsed or refractory myelofibrosis (NCT03662126), with reported activity also in acute myeloid leukaemia and Merkel cell carcinoma. Kartos is led by CEO Jesse McGreivy, MD, with Srdan Verstovsek, MD, PhD as chief medical officer, and is backed by Quogue Capital, OrbiMed Advisors, Amgen, SR One, Fidelity, BlackRock, T. Rowe Price, Invus and Soleus Capital. Kartos Therapeutics runs no developer program and publishes no product API, no developer portal and no API documentation; the only machine-readable surface reachable without credentials is the WordPress REST content API behind kartosthera.com, catalogued here. image: https://kartosthera.com/wp-content/uploads/2025/10/og_kartos-therapeutics.jpg url: https://raw.githubusercontent.com/api-evangelist/kartos-therapeutics/refs/heads/main/apis.yml x-type: company x-source: harvest:secondary-market x-tier: profiled x-tier-reason: enriched specificationVersion: '0.20' created: '2026-08-04' modified: '2026-08-04' tags: - Company - biotechnology - pharmaceuticals - oncology - hematology - rare-disease - precision-medicine - clinical-trials - life-sciences - content-api apis: - aid: kartos-therapeutics:kartos-therapeutics-content-api name: Kartos Therapeutics Content API description: Published pages and the site-wide search index. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://kartosthera.com/wp-json tags: - content properties: - type: OpenAPI url: openapi/kartos-therapeutics-content-api-openapi.yml - type: Authentication url: authentication/kartos-therapeutics-authentication.yml - type: ErrorCatalog url: errors/kartos-therapeutics-problem-types.yml - type: Conventions url: conventions/kartos-therapeutics-conventions.yml - type: DataModel url: data-model/kartos-therapeutics-data-model.yml - aid: kartos-therapeutics:kartos-therapeutics-discovery-api name: Kartos Therapeutics Discovery API description: The route index and namespace descriptors the site publishes about itself. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://kartosthera.com/wp-json tags: - discovery properties: - type: OpenAPI url: openapi/kartos-therapeutics-discovery-api-openapi.yml - type: Authentication url: authentication/kartos-therapeutics-authentication.yml - type: ErrorCatalog url: errors/kartos-therapeutics-problem-types.yml - type: Conventions url: conventions/kartos-therapeutics-conventions.yml - type: DataModel url: data-model/kartos-therapeutics-data-model.yml - aid: kartos-therapeutics:kartos-therapeutics-media-api name: Kartos Therapeutics Media API description: The media library — scientific figures, investor logos and presentation PDFs. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://kartosthera.com/wp-json tags: - media properties: - type: OpenAPI url: openapi/kartos-therapeutics-media-api-openapi.yml - type: Authentication url: authentication/kartos-therapeutics-authentication.yml - type: ErrorCatalog url: errors/kartos-therapeutics-problem-types.yml - type: Conventions url: conventions/kartos-therapeutics-conventions.yml - type: DataModel url: data-model/kartos-therapeutics-data-model.yml - aid: kartos-therapeutics:kartos-therapeutics-oembed-api name: Kartos Therapeutics Oembed API description: The oEmbed 1.0 provider endpoint for kartosthera.com URLs. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://kartosthera.com/wp-json tags: - oembed properties: - type: OpenAPI url: openapi/kartos-therapeutics-oembed-api-openapi.yml - type: Authentication url: authentication/kartos-therapeutics-authentication.yml - type: ErrorCatalog url: errors/kartos-therapeutics-problem-types.yml - type: Conventions url: conventions/kartos-therapeutics-conventions.yml - type: DataModel url: data-model/kartos-therapeutics-data-model.yml - aid: kartos-therapeutics:kartos-therapeutics-people-api name: Kartos Therapeutics People API description: The leadership, board and advisor team custom post type. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://kartosthera.com/wp-json tags: - people properties: - type: OpenAPI url: openapi/kartos-therapeutics-people-api-openapi.yml - type: Authentication url: authentication/kartos-therapeutics-authentication.yml - type: ErrorCatalog url: errors/kartos-therapeutics-problem-types.yml - type: Conventions url: conventions/kartos-therapeutics-conventions.yml - type: DataModel url: data-model/kartos-therapeutics-data-model.yml - aid: kartos-therapeutics:kartos-therapeutics-science-api name: Kartos Therapeutics Science API description: The navtemadlin congress presentations and publications custom post type. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://kartosthera.com/wp-json tags: - science properties: - type: OpenAPI url: openapi/kartos-therapeutics-science-api-openapi.yml - type: Authentication url: authentication/kartos-therapeutics-authentication.yml - type: ErrorCatalog url: errors/kartos-therapeutics-problem-types.yml - type: Conventions url: conventions/kartos-therapeutics-conventions.yml - type: DataModel url: data-model/kartos-therapeutics-data-model.yml - aid: kartos-therapeutics:kartos-therapeutics-taxonomy-api name: Kartos Therapeutics Taxonomy API description: Registered post types, statuses, taxonomies and terms. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://kartosthera.com/wp-json tags: - taxonomy properties: - type: OpenAPI url: openapi/kartos-therapeutics-taxonomy-api-openapi.yml - 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type: SecondaryMarket url: https://forgeglobal.com/kartos-therapeutics_stock/ - type: Authentication url: authentication/kartos-therapeutics-authentication.yml - type: Conventions url: conventions/kartos-therapeutics-conventions.yml - type: Conformance url: conformance/kartos-therapeutics-conformance.yml - type: ErrorCatalog url: errors/kartos-therapeutics-problem-types.yml - type: Lifecycle url: lifecycle/kartos-therapeutics-lifecycle.yml - type: DataModel url: data-model/kartos-therapeutics-data-model.yml - type: WellKnown url: well-known/kartos-therapeutics-well-known.yml - type: DomainSecurity url: security/kartos-therapeutics-domain-security.yml - type: LLMsTxt url: llms/kartos-therapeutics-llms.txt - type: AgentSkill url: skills/_index.yml x-enrichment: date: '2026-08-04' status: enriched artifacts_added: 15 pass: local-v1