# Provenance stamped 2026-10-07 (roadmap#943): written by an API Evangelist sweep (undated — the file carries no date and git cannot supply one), not # harvested from the provider. `method: generated` so the economics campaign may replace it with a # dated, verbatim transcription; every figure below is unverified until it does. # Coverage demoted 2026-10-07 (roadmap#942, PLAN.md Stage A): this file was written by an API Evangelist # sweep and names no billing unit, meters or pricing category read from the provider — it restates the # FinOps framework. It is `x-coverage: unmeasured`, and the FOCUS alignment it claimed has been removed. x-coverage: unmeasured method: generated name: KEGG APIs Financial Overview description: > The KEGG REST API is free for academic users with no registration required. Costs arise only when academic researchers need bulk FTP data downloads (annual subscription ~$2,000–$5,000 USD) or when commercial entities require a license through Pathway Solutions (pricing by inquiry). There are no per-call charges, no data egress fees from the REST API, and no tiered usage-based pricing. The primary financial consideration for high-volume users is the operational cost of their own infrastructure for processing retrieved data, and the subscription fees for FTP access if REST API rate limits are insufficient for their workflow. provider: Kyoto Encyclopedia of Genes and Genomes (KEGG) url: https://www.kegg.jp/kegg/rest/ funding: model: > KEGG is operated by the Kanehisa Laboratory at Kyoto University and the Human Genome Center at the University of Tokyo, with commercial licensing managed by Pathway Solutions (Japan). Historically funded by academic grants; a subscription model was introduced to sustain operations as grant funding declined. cost: Free for academic REST API access; subscription or license required for FTP and commercial use apis: - name: KEGG REST API cost: Free (academic use only) apiKey: Not required notes: > All seven operations (info, list, find, get, conv, link, ddi) are free for academic users. No registration, API key, or credit card is needed. Rate limit of 3 req/s is enforced. Commercial use without a license is prohibited. - name: KEGG FTP Academic Subscription — End User cost: ~$2,000 USD per year apiKey: Not applicable (FTP credential provided on subscription) notes: > Annual subscription for a laboratory or department needing weekly-updated bulk FTP data. Pricing approximate; confirm via pathway.jp request form. - name: KEGG FTP Academic Subscription — Service Provider cost: ~$5,000 USD per year apiKey: Not applicable (FTP credential provided on subscription) notes: > Annual subscription for research groups deploying KEGG-based tools or web services. Includes academic service provider license. Pricing approximate; confirm via pathway.jp request form. - name: Commercial License cost: Pricing on request apiKey: Not applicable notes: > Commercial End User and Service Provider licenses available through Pathway Solutions (pathway.jp/en/licensing.html). Terms are non-negotiable. Includes optional KEGG mirror site and API access. cost_drivers: - factor: REST API calls impact: None — REST API is free and has no per-call charge - factor: FTP bulk data subscription impact: High — required for bulk downloads or local KEGG mirror; $2k–$5k/year academic - factor: Commercial licensing impact: High — required for any non-academic production use; pricing by inquiry - factor: Own infrastructure impact: Variable — compute and storage costs for processing KEGG data are borne by the user optimization: - Use the CONV and LINK operations to minimize round-trips when mapping identifiers - Batch up to 10 entries per GET call to maximize throughput within the 3 req/s limit - For academic bulk-data needs, evaluate the FTP subscription vs. repeated REST polling - Cache pathway images and flat-file entries locally to avoid redundant API calls