openapi: 3.1.0 info: title: KEGG REST conv API description: 'The Kyoto Encyclopedia of Genes and Genomes (KEGG) REST API provides programmatic access to KEGG databases covering biological pathways, metabolic networks, molecular interactions, drug targets, disease associations, chemical compounds, genomic sequences, and functional orthologs across thousands of organisms. The API exposes seven core operations — info, list, find, get, conv, link, and ddi — enabling identifier conversion, cross-database linking, keyword and structure searches, and full entry retrieval in text, KGML, and JSON formats. Academic use is free; commercial use requires a license from Pathway Solutions. Rate limit is 3 requests per second per client. ' version: 1.0.0 contact: name: KEGG Support url: https://www.kegg.jp/kegg/feedback.html termsOfService: https://www.kegg.jp/kegg/legal.html license: name: Academic Use Only url: https://www.kegg.jp/kegg/legal.html servers: - url: https://rest.kegg.jp description: KEGG REST API server tags: - name: conv description: Convert identifiers between KEGG and external databases paths: /conv/{target_db}/{source_db}: get: operationId: convertIdentifiers summary: Convert identifiers between databases description: 'Convert identifiers between KEGG and external databases. Returns a tab-delimited mapping of source to target identifiers. Supports conversion between KEGG gene identifiers and NCBI Gene IDs, NCBI Protein IDs, and UniProt accessions, as well as between KEGG compound IDs and PubChem CIDs and ChEBI IDs. ' tags: - conv parameters: - name: target_db in: path required: true description: 'Target database for conversion. For genes: ncbi-geneid, ncbi-proteinid, uniprot, or a KEGG organism code. For chemicals: pubchem, chebi, or compound. ' schema: type: string example: ncbi-geneid - name: source_db in: path required: true description: 'Source database or organism code. For genes: ncbi-geneid, ncbi-proteinid, uniprot, or a KEGG organism code. For chemicals: pubchem, chebi, or compound. ' schema: type: string example: hsa responses: '200': description: Tab-delimited identifier mapping content: text/plain: schema: type: string example: "ncbi-geneid:10458\thsa:10458\nncbi-geneid:1131\thsa:1131\n" '400': description: Bad request '404': description: Not found /conv/{target_db}/{dbentries}: get: operationId: convertEntryIdentifiers summary: Convert specific entry identifiers description: 'Convert specific KEGG entry identifiers to their equivalents in an external database, or convert external database identifiers to KEGG identifiers. Up to 10 entries per request. ' tags: - conv parameters: - name: target_db in: path required: true description: 'Target database for conversion (e.g., ncbi-geneid, uniprot, pubchem, chebi, or a KEGG organism code). ' schema: type: string - name: dbentries in: path required: true description: 'One or more entry identifiers separated by plus signs. Maximum 10 entries per request. ' schema: type: string example: ncbi-geneid:10458+ncbi-geneid:1131 responses: '200': description: Tab-delimited identifier mapping content: text/plain: schema: type: string '400': description: Bad request '404': description: Not found externalDocs: description: KEGG API Documentation url: https://www.kegg.jp/kegg/rest/keggapi.html