aid: laronde
name: Sail Biomedicines
description: >-
  Sail Biomedicines is a Cambridge, Massachusetts preclinical biotechnology company created in
  October 2023 by Flagship Pioneering through the merger of Laronde and Senda Biosciences, and it
  is the company this profile's legacy `laronde` slug refers to. Sail combines Laronde's Endless
  RNA (eRNA) platform — synthetic circular RNA engineered to be translated persistently inside the
  body — with Senda's programmable lipid and natural nanoparticle delivery chemistry, and layers
  generative AI on the combined dataset to design what the company calls fully programmable
  medicines. Its lead effort is in vivo CAR-T for autoimmune disease: instructing a patient's own
  T cells to reprogram themselves inside the body rather than extracting, engineering and
  reinfusing them, an approach Sail markets as "immune reset". In July 2026 Johnson & Johnson
  committed $785 million up front (including a $465 million equity investment) plus up to $140
  million in milestones and took an exclusive option to acquire the company for a further $2.58
  billion. Sail sells therapeutics, not software: it publishes no API, no SDK, no machine-readable
  specification and no developer documentation, and it operates no public source-code organization.
url: https://raw.githubusercontent.com/api-evangelist/laronde/refs/heads/main/apis.yml
image: https://www.sail.bio/wp-content/uploads/2024/05/sail-logo-primary-dark.svg
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pipeline
specificationVersion: '0.23'
created: '2026-08-23'
modified: '2026-08-23'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- RNA
- Circular RNA
- Cell Therapy
- CAR-T
- Nanoparticles
- Drug Discovery
- Immunology
- Autoimmune Disease
- Life Sciences
- Artificial Intelligence
- Preclinical
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/laronde-domain-security.yml
- type: Website
  url: https://www.sail.bio/
- type: About
  url: https://www.sail.bio/about-us/
- type: News
  url: https://www.sail.bio/news/
- type: Blog
  url: https://www.sail.bio/news/
- type: BlogRSS
  url: https://www.sail.bio/feed/
- type: Careers
  url: https://www.sail.bio/careers/
- type: Contact
  url: https://www.sail.bio/contact/
- type: TermsOfService
  url: https://www.sail.bio/terms-of-service/
- type: PrivacyPolicy
  url: https://www.sail.bio/privacy-policy/
- type: LinkedIn
  url: https://www.linkedin.com/company/sail-biomedicines
- type: Twitter
  url: https://twitter.com/SailBiomeds
- type: Investor
  url: https://www.flagshippioneering.com/companies/sail-biomedicines
- type: SecondaryMarket
  url: https://forgeglobal.com/laronde_stock/
- type: LLMsTxt
  url: llms/laronde-llms.txt
- type: Packages
  url: packages/laronde-packages.yml
- type: Plans
  url: plans/laronde-plans-pricing.yml
- type: RateLimits
  url: rate-limits/laronde-rate-limits.yml
x-enrichment:
  date: '2026-08-23'
  status: minimal
  artifacts_added: 6
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: >-
    Sail Biomedicines (the company behind this profile's legacy `laronde` slug, formed when
    Flagship Pioneering merged Laronde and Senda Biosciences in October 2023) is a preclinical
    biopharmaceutical company whose product is an in vivo CAR-T drug pipeline, not software —
    www.sail.bio is a 14-page WordPress marketing site on WP Engine that returns an honest 404 for
    every OpenAPI, GraphQL, llms.txt and /.well-known/ path, api./docs./developer./data./mcp. and
    every other developer subdomain are NXDOMAIN, and no package exists on npm, PyPI, RubyGems or
    crates.io; the site's only machine-readable surface is the stock WordPress core REST API at
    /wp-json/, which is the CMS, not a published API.
  evidence:
  - url: https://www.sail.bio/
    status: 200
  - url: https://www.sail.bio/openapi.json
    status: 404
  - url: https://www.sail.bio/graphql
    status: 404
  - url: https://www.sail.bio/llms.txt
    status: 404
  - url: https://www.sail.bio/.well-known/security.txt
    status: 404
  - url: https://www.sail.bio/.well-known/agent-card.json
    status: 404
  - url: https://www.sail.bio/wp-json/
    status: 200
  - url: https://pypi.org/pypi/sailbio/json
    status: 404
  checked: '2026-08-23'