aid: life-sciences url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/apis.yml name: Life Sciences type: Index image: https://kinlane-productions.s3.amazonaws.com/apis-json/apis-json-logo.jpg tags: - Life Sciences - Biotech - Pharma - Healthcare - Clinical Trials - Drug Information - Genomics - Bioinformatics - EHR - FHIR - Lab Informatics description: >- Industry-vertical index for the life sciences, biotechnology, and pharmaceutical landscape. Catalogs the major public and commercial APIs spanning clinical trial registries, drug and regulatory data, genomic reference data, electronic health record exchange, laboratory informatics systems, and bioinformatics pipeline platforms. The catalog is anchored by shared schemas for the three core records that recur across this domain: the clinical trial, the drug, and the gene. created: '2025-01-01' modified: '2026-05-23' specificationVersion: '0.19' apis: - name: ClinicalTrials.gov API v2 description: >- The U.S. National Library of Medicine's modernized REST/JSON API for the ClinicalTrials.gov registry. Provides programmatic access to records of privately and publicly funded clinical studies conducted around the world, replacing the legacy AACT/full-study download path with a JSON-first interface and OpenAPI specification. humanURL: https://clinicaltrials.gov/data-api/api baseURL: https://clinicaltrials.gov/api/v2/ tags: - Clinical Trials - Registry - NIH - NLM - Public Data properties: - type: Documentation url: https://clinicaltrials.gov/data-api/api - type: Documentation url: https://clinicaltrials.gov/data-api/about-api title: About the API - type: OpenAPI url: https://clinicaltrials.gov/api/v2/swagger.yaml title: ClinicalTrials.gov v2 OpenAPI - type: JSONSchema url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/clinical-trial-schema.json title: Clinical Trial Schema - type: Example url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/examples/clinical-trial-example.json title: Clinical Trial Example - name: EU Clinical Trials Register / CTIS description: >- The European Medicines Agency's Clinical Trials Information System (CTIS) and the legacy EU Clinical Trials Register. CTIS is the single entry point for sponsors and regulators across the EU/EEA to submit and supervise clinical trials under Regulation (EU) No 536/2014. Public lookup is offered through a web portal; bulk and integration interfaces are not openly published as REST APIs. humanURL: https://euclinicaltrials.eu/ baseURL: https://euclinicaltrials.eu/ctis-public/ tags: - Clinical Trials - EU - EMA - Regulator - CTIS properties: - type: Documentation url: https://euclinicaltrials.eu/ - type: Documentation url: https://www.ema.europa.eu/en/human-regulatory-overview/research-development/clinical-trials-human-medicines/clinical-trials-information-system title: EMA CTIS overview - type: HumanInterface url: https://www.clinicaltrialsregister.eu/ title: Legacy EU Clinical Trials Register - name: openFDA description: >- A U.S. Food and Drug Administration project that exposes public FDA data via a single Elasticsearch-backed REST/JSON API. Covers adverse-event reports, drug labels, recalls, NDC directory, device 510(k) and adverse events, food enforcement, tobacco problem reports, and animal/vet adverse events. humanURL: https://open.fda.gov/ baseURL: https://api.fda.gov/ tags: - FDA - Drug - Device - Food - Adverse Events - Regulator properties: - type: Documentation url: https://open.fda.gov/apis/ - type: Documentation url: https://open.fda.gov/apis/drug/ title: Drug endpoints - type: Documentation url: https://open.fda.gov/apis/device/ title: Device endpoints - type: Documentation url: https://open.fda.gov/apis/food/ title: Food endpoints - type: GitHubRepository url: https://github.com/FDA/openfda - type: JSONSchema url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/drug-schema.json title: Drug Schema - type: Example url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/examples/drug-example.json title: Drug Example - name: DailyMed description: >- The National Library of Medicine's authoritative source of FDA-approved Structured Product Labeling (SPL) for prescription and over-the-counter medications marketed in the United States. Exposes a REST/JSON web services API for searching and retrieving SPL documents by SET ID, NDC, RxCUI, and other identifiers. humanURL: https://dailymed.nlm.nih.gov/dailymed/ baseURL: https://dailymed.nlm.nih.gov/dailymed/services/v2/ tags: - Drug Information - Labeling - SPL - NLM properties: - type: Documentation url: https://dailymed.nlm.nih.gov/dailymed/app-support-web-services.cfm title: DailyMed Web Services - name: RxNorm API description: >- The National Library of Medicine's web service for accessing RxNorm, the standardized nomenclature for clinical drugs that links names of drugs across the major U.S. drug vocabularies. Supports name-to-RxCUI resolution, NDC lookup, relationship traversal, interaction discovery via RxNav, and approximate matching. humanURL: https://lhncbc.nlm.nih.gov/RxNav/APIs/RxNormAPIs.html baseURL: https://rxnav.nlm.nih.gov/REST/ tags: - Drug Information - Terminology - NLM - RxNorm properties: - type: Documentation url: https://lhncbc.nlm.nih.gov/RxNav/APIs/RxNormAPIs.html - type: Documentation url: https://lhncbc.nlm.nih.gov/RxNav/APIs/InteractionAPIs.html title: Interaction API - type: JSONSchema url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/drug-schema.json title: Drug Schema - name: DrugBank API description: >- A commercial drug knowledge API providing curated pharmacology, pharmacokinetics, drug-drug interaction, indication, and identifier cross-walk data covering small molecules and biologics. Used by clinical decision support, electronic prescribing, and pharmacy systems. humanURL: https://docs.drugbank.com/v1/ baseURL: https://api.drugbankplus.com/v1/ tags: - Drug Information - Pharmacology - Interactions - Commercial properties: - type: Documentation url: https://docs.drugbank.com/v1/ - type: Documentation url: https://go.drugbank.com/ title: DrugBank Online - name: NCBI Entrez E-utilities description: >- The set of nine programmatic interfaces (ESearch, EPost, ESummary, EFetch, ELink, EInfo, EGQuery, ESpell, ECitMatch) that provide unified access to all NCBI databases including PubMed, Gene, Genome, Nucleotide, Protein, ClinVar, dbSNP, dbGaP, BioProject, BioSample, GEO, and Taxonomy. humanURL: https://www.ncbi.nlm.nih.gov/books/NBK25500/ baseURL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/ tags: - Genomics - Bioinformatics - NCBI - PubMed - Reference Data properties: - type: Documentation url: https://www.ncbi.nlm.nih.gov/books/NBK25500/ - type: Documentation url: https://www.ncbi.nlm.nih.gov/books/NBK25501/ title: A General Introduction to the E-utilities - type: JSONSchema url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/gene-schema.json title: Gene Schema - name: Ensembl REST API description: >- The European Bioinformatics Institute's REST/JSON interface to the Ensembl genome browser. Provides programmatic access to genomic annotation, variation, comparative genomics, regulatory data, the Variant Effect Predictor (VEP), and GA4GH-compatible variation endpoints across vertebrate, invertebrate, plant, and fungal genomes. humanURL: https://rest.ensembl.org/ baseURL: https://rest.ensembl.org/ tags: - Genomics - Variation - VEP - EBI - GA4GH properties: - type: Documentation url: https://rest.ensembl.org/ - type: Documentation url: https://rest.ensembl.org/documentation/info/vep_hgvs_get title: VEP endpoints - type: JSONSchema url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/gene-schema.json title: Gene Schema - type: Example url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/examples/gene-example.json title: Gene Example - name: UCSC Genome Browser REST API description: >- The University of California Santa Cruz Genome Browser's REST API for programmatic retrieval of assemblies, tracks, sequences, and annotations across the genomes hosted in the UCSC Browser, including human (hg19, hg38, T2T-CHM13), mouse, and many other species. humanURL: https://genome.ucsc.edu/goldenPath/help/api.html baseURL: https://api.genome.ucsc.edu/ tags: - Genomics - Reference Genome - UCSC - Tracks properties: - type: Documentation url: https://genome.ucsc.edu/goldenPath/help/api.html - name: ClinVar (via E-utilities) description: >- The NIH/NLM database of relationships among human genomic variation and phenotype, with supporting evidence. Accessible programmatically via Entrez E-utilities and via a structured FTP feed of XML/JSON variant submissions. humanURL: https://www.ncbi.nlm.nih.gov/clinvar/ baseURL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/ tags: - Variation - Clinical Genomics - NCBI - ClinVar properties: - type: Documentation url: https://www.ncbi.nlm.nih.gov/clinvar/docs/maintenance_use/ - type: Documentation url: https://www.ncbi.nlm.nih.gov/clinvar/docs/linking/ title: Linking to ClinVar - name: dbSNP (via E-utilities) description: >- The NCBI Short Genetic Variations database, the canonical reference for single nucleotide polymorphisms (SNPs) and small insertions/deletions in humans and other organisms. Accessed via Entrez E-utilities using the `snp` database. humanURL: https://www.ncbi.nlm.nih.gov/snp/ baseURL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/ tags: - Variation - SNP - NCBI - dbSNP properties: - type: Documentation url: https://www.ncbi.nlm.nih.gov/snp/docs/ - name: HL7 FHIR description: >- Fast Healthcare Interoperability Resources (FHIR) is HL7's standard for health care data exchange. The current normative version is R5, released March 2023. Defines roughly 150 resource types covering administration, clinical care, diagnostics, medications, workflow, financial, and foundation domains, exchanged over REST, messaging, or document paradigms. humanURL: https://www.hl7.org/fhir/ baseURL: https://hl7.org/fhir/R5/ tags: - FHIR - HL7 - EHR - Healthcare Interoperability - Standard properties: - type: Documentation url: https://www.hl7.org/fhir/ - type: Specification url: https://hl7.org/fhir/R5/ title: FHIR R5 specification - type: JSONSchema url: https://hl7.org/fhir/R5/fhir.schema.json.zip title: FHIR JSON Schema (official) - type: GitHubRepository url: https://github.com/HL7/fhir - name: SMART on FHIR description: >- An open-spec authorization profile layered on top of FHIR that enables third-party clinical applications to launch within an EHR session with OAuth 2.0 / OpenID Connect scopes scoped to FHIR resources. humanURL: https://docs.smarthealthit.org/ baseURL: https://docs.smarthealthit.org/ tags: - FHIR - SMART - OAuth - EHR - Standard properties: - type: Documentation url: https://docs.smarthealthit.org/ - type: GitHubRepository url: https://github.com/smart-on-fhir - name: Benchling Developer Platform description: >- Benchling's REST API and webhook platform for its R&D cloud, exposing programmatic access to the Notebook (entries), Registry (registered entities, sequences, plasmids), Inventory (boxes, plates, locations), Requests, Results, Schemas, and Projects domains used across biotech R&D organizations. humanURL: https://docs.benchling.com/ baseURL: https://{tenant}.benchling.com/api/v2/ tags: - Lab Informatics - ELN - LIMS - Biotech - Commercial properties: - type: Documentation url: https://docs.benchling.com/ - type: Documentation url: https://docs.benchling.com/reference title: API reference - name: TetraScience Data Platform description: >- A cloud-native scientific data platform that harmonizes instrument and informatics data across pharma R&D. Exposes REST APIs and SDKs for ingesting, querying, and integrating laboratory and computational data using the Intermediate Data Schema (IDS). humanURL: https://developers.tetrascience.com/ baseURL: https://developers.tetrascience.com/ tags: - Lab Informatics - Scientific Data - IDS - Commercial properties: - type: Documentation url: https://developers.tetrascience.com/ - name: Sapio Sciences ELN/LIMS API description: >- Sapio Sciences' platform API providing programmatic access to its Electronic Laboratory Notebook, Laboratory Information Management System, and Scientific Data Cloud, covering samples, experiments, assay results, and inventory. humanURL: https://www.sapiosciences.com/ baseURL: https://www.sapiosciences.com/ tags: - Lab Informatics - ELN - LIMS - Commercial properties: - type: Documentation url: https://www.sapiosciences.com/ - name: DNAnexus Platform API description: >- DNAnexus is a cloud bioinformatics platform used by pharma, biotech, and research institutions to run genomic and biomedical compute workflows. Its platform API provides programmatic access to projects, files, apps, workflows, jobs, and analyses for petabyte-scale genomic data. humanURL: https://documentation.dnanexus.com/ baseURL: https://api.dnanexus.com/ tags: - Bioinformatics - Cloud Compute - Workflows - Commercial properties: - type: Documentation url: https://documentation.dnanexus.com/ - type: Documentation url: https://documentation.dnanexus.com/developer/api title: Developer / API reference - name: Seven Bridges (Velsera) Platform API description: >- A multi-cloud bioinformatics platform (now part of Velsera) offering hosted instances of the NCI Cancer Genomics Cloud and other cohort analysis environments. Provides REST APIs for projects, files, tasks, and apps written in CWL. humanURL: https://docs.sevenbridges.com/ baseURL: https://api.sbgenomics.com/v2/ tags: - Bioinformatics - Cloud Compute - CWL - Cancer Genomics properties: - type: Documentation url: https://docs.sevenbridges.com/ - name: Galaxy Project API description: >- The open-source Galaxy bioinformatics workbench exposes a REST API for managing histories, datasets, workflows, tools, jobs, and users across community Galaxy servers and self-hosted installations. humanURL: https://docs.galaxyproject.org/en/latest/api_doc.html baseURL: https://usegalaxy.org/api/ tags: - Bioinformatics - Open Source - Workflows - Galaxy properties: - type: Documentation url: https://docs.galaxyproject.org/en/latest/api_doc.html - type: GitHubRepository url: https://github.com/galaxyproject/galaxy - name: GA4GH APIs (htsget, DRS, WES, TES, Beacon) description: >- The Global Alliance for Genomics and Health publishes a suite of open REST specifications enabling federated access to genomic data and compute. Includes htsget (sequencing reads), DRS (Data Repository Service), WES (Workflow Execution Service), TES (Task Execution Service), and the Beacon variant-discovery protocol. humanURL: https://www.ga4gh.org/genomic-data-toolkit/ baseURL: https://www.ga4gh.org/ tags: - Genomics - Standard - GA4GH - Federated properties: - type: Documentation url: https://www.ga4gh.org/genomic-data-toolkit/ - type: GitHubRepository url: https://github.com/ga4gh - type: Specification url: https://samtools.github.io/hts-specs/htsget.html title: htsget specification - type: Specification url: https://ga4gh.github.io/beacon/ title: Beacon specification json-schemas: - title: Clinical Trial url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/clinical-trial-schema.json - title: Drug url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/drug-schema.json - title: Gene url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/gene-schema.json json-ld: - title: Life Sciences Context url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-ld/life-sciences-context.jsonld vocabulary: - title: Life Sciences Vocabulary url: >- https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/vocabulary/life-sciences-vocabulary.yaml maintainers: - FN: Kin Lane email: info@apievangelist.com url: https://apievangelist.com