{ "nctId": "NCT04280705", "officialTitle": "Adaptive COVID-19 Treatment Trial (ACTT)", "briefTitle": "Adaptive COVID-19 Treatment Trial", "status": "Completed", "phase": ["Phase 3"], "studyType": "Interventional", "conditions": ["COVID-19", "SARS-CoV-2 Infection"], "interventions": [ { "type": "Drug", "name": "Remdesivir", "description": "200 mg loading dose on day 1, followed by 100 mg daily for up to 9 additional days" }, { "type": "Drug", "name": "Placebo", "description": "Matching placebo administered on the same schedule" } ], "sponsor": { "name": "National Institute of Allergy and Infectious Diseases (NIAID)", "class": "NIH" }, "locations": [ { "facility": "University of Nebraska Medical Center", "city": "Omaha", "state": "Nebraska", "country": "United States", "status": "Completed" } ], "enrollment": { "count": 1062, "type": "Actual" }, "startDate": "2020-02-21", "completionDate": "2020-04-19", "primaryOutcomes": [ { "measure": "Time to recovery", "timeFrame": "Day 1 through Day 29", "description": "Days until participant met the recovery criterion of being well enough for hospital discharge" } ], "eligibility": { "criteria": "Hospitalized adults with laboratory-confirmed SARS-CoV-2 infection and evidence of lower respiratory tract involvement", "sex": "All", "minimumAge": "18 Years", "healthyVolunteers": false }, "url": "https://clinicaltrials.gov/study/NCT04280705" }