aid: lygenesis
name: LyGenesis
description: 'LyGenesis is a Pittsburgh-based clinical-stage cell therapy company developing
  allogeneic regenerative therapies that use a patient''s own lymph nodes as bioreactors
  to grow functioning ectopic organs. Its lead program transplants donor hepatocytes into
  upper-abdominal lymph nodes via endoscopic ultrasound to treat end-stage liver disease
  and is in a Phase 2a clinical trial; preclinical proof-of-concept programs target thymus
  (aging), kidney (end-stage renal disease) and pancreas (Type 1 diabetes). LyGenesis is a
  laboratory and clinical-research organization, not a software vendor: it publishes no
  developer portal, no API documentation and no machine-readable API contract, and this
  profile records that absence rather than any API surface.'
url: https://raw.githubusercontent.com/api-evangelist/lygenesis/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
specificationVersion: '0.20'
created: '2026-08-25'
modified: '2026-08-25'
tags:
- Company
- Biotechnology
- Cell Therapy
- Regenerative Medicine
- Life Sciences
- Healthcare
- Clinical Trials
- Organ Transplantation
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://www.lygenesis.com/
- type: PrivacyPolicy
  url: https://www.lygenesis.com/privacy-policy/
- type: Support
  url: https://www.lygenesis.com/contact/
- type: Blog
  url: https://www.lygenesis.com/media/insights/
- type: LinkedIn
  url: https://www.linkedin.com/company/lygenesis/
- type: Twitter
  url: https://twitter.com/LyGenesis_Inc
- type: DomainSecurity
  url: security/lygenesis-domain-security.yml
- type: LLMsTxt
  url: llms/lygenesis-llms.txt
x-enrichment:
  date: '2026-08-25'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: >-
    LyGenesis is a clinical-stage cell therapy company whose product is a lymph-node
    organogenesis therapy in a Phase 2a trial, not software: its www.lygenesis.com Nuxt
    site 404s on every spec and /.well-known/ path, api./developer./docs.lygenesis.com
    do not resolve, and there is no GitHub org, npm or PyPI package.
  evidence:
  - url: https://www.lygenesis.com/openapi.json
    status: 404
  - url: https://www.lygenesis.com/.well-known/agent-card.json
    status: 404
  - url: https://www.lygenesis.com/llms.txt
    status: 404
  - url: https://api.github.com/search/repositories?q=lygenesis
    status: 200
  checked: '2026-08-25'