aid: matchpoint-therapeutics name: Matchpoint Therapeutics description: >- Matchpoint Therapeutics is a privately held biotechnology company headquartered in Watertown, Massachusetts — Cambridge at launch — that discovers precision small-molecule covalent medicines intended to transform the treatment of immune diseases and other serious illness. It was founded by covalent-chemistry, proteomics and computational-science researchers from Stanford University and Harvard Medical School, closed a $30 million seed round co-led by Atlas Venture and Access Biotechnology in November 2021, and launched publicly in October 2022 with $100 million in total financing after a $70 million Series A led by Sanofi Ventures with Vertex Ventures HC, Digitalis Ventures and Alexandria Venture Investments. Its proprietary Advanced Covalent Exploration (ACE) platform combines industry-leading chemoproteomics that detects allosteric, transient and cryptic binding pockets in native cells, machine-learning algorithms that prioritise targets and guide medicinal chemistry, and a continuously evolving proprietary library of covalent compounds spanning fragments through drug-like leads. In July 2025 Matchpoint entered an exclusive option and licence agreement with Novartis to develop oral covalent inhibitors against a transcription factor linked to multiple inflammatory diseases, worth up to $60 million upfront and in research funding and up to $1 billion in total potential payments. Matchpoint runs no developer program and publishes no product API, developer portal, API reference or SDK. The only machine-readable surface reachable without credentials is the WordPress REST content API behind matchpointtx.com, catalogued here. deliveryModel: model: saas open_source: false commercial: true callable_host: true label: Hosted service · you call their endpoint confidence: high source: - openapi - pricing generated: '2026-08-28' method: derived image: https://matchpointtx.com/wp-content/uploads/2022/09/logo-matchpoint.png url: https://raw.githubusercontent.com/api-evangelist/matchpoint-therapeutics/refs/heads/main/apis.yml x-type: company x-source: harvest:secondary-market x-tier: profiled x-tier-reason: enriched specificationVersion: '0.23' created: '2026-08-25' modified: '2026-08-25' tags: - Company - Biotechnology - Pharmaceuticals - Drug Discovery - Immunology - Covalent Chemistry - chemoproteomics - Machine-Learning - Life Sciences - content-api tags_raw: - Company - biotechnology - pharmaceuticals - drug-discovery - immunology - covalent-chemistry - chemoproteomics - machine-learning - life-sciences - content-api apis: - aid: matchpoint-therapeutics:matchpoint-therapeutics-comments-api name: Matchpoint Therapeutics Comments API description: >- Comment collection. Registered and reachable, but empty — no object on this deployment carries comments. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Comments tags_raw: - comments properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-comments-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-discovery-api name: Matchpoint Therapeutics Discovery API description: Route, type, taxonomy and status discovery documents. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Discovery tags_raw: - discovery properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-discovery-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-media-api name: Matchpoint Therapeutics Media API description: Media library — 43 image attachments at harvest time. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Media tags_raw: - media properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-media-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-oembed-api name: Matchpoint Therapeutics Oembed API description: oEmbed 1.0 provider endpoint for matchpointtx.com URLs. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - oEmbed tags_raw: - oembed properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-oembed-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-pages-api name: Matchpoint Therapeutics Pages API description: Corporate pages — homepage, privacy policy, terms of use (3 published at harvest time). humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Pages tags_raw: - pages properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-pages-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-posts-api name: Matchpoint Therapeutics Posts API description: >- News archive — company press releases and third-party coverage (5 published at harvest time). humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Posts tags_raw: - posts properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-posts-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-search-api name: Matchpoint Therapeutics Search API description: Cross-content search across published objects. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Search tags_raw: - search properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-search-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-taxonomy-api name: Matchpoint Therapeutics Taxonomy API description: >- Categories, post tags and the team_types taxonomy. Only one category term exists; post_tag and team_types are registered but empty. humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Taxonomy tags_raw: - taxonomy properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-taxonomy-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - aid: matchpoint-therapeutics:matchpoint-therapeutics-team-api name: Matchpoint Therapeutics Team API description: >- Leadership, board, observers and scientific founders as a custom post type (19 published at harvest time). humanURL: https://developer.wordpress.org/rest-api/ baseURL: https://matchpointtx.com/wp-json tags: - Team tags_raw: - team properties: - type: OpenAPI url: openapi/matchpoint-therapeutics-team-api-openapi.yml - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml maintainers: - FN: Kin Lane email: kin@apievangelist.com - FN: APIs.json email: info@apis.io common: - type: Website url: https://matchpointtx.com/ - type: BlogRSS url: https://matchpointtx.com/feed/ - type: Careers url: https://boards.greenhouse.io/matchpointtx - type: PrivacyPolicy url: https://matchpointtx.com/privacy-policy/ - type: TermsOfService url: https://matchpointtx.com/terms-conditions/ - type: LinkedIn url: https://www.linkedin.com/company/matchpoint-therapeutics - type: Twitter url: https://twitter.com/matchpointtx - type: SecondaryMarket url: https://www.nasdaqprivatemarket.com/company/matchpoint-therapeutics/ - type: SecondaryMarket url: https://equityzen.com/company/matchpointtherapeutics/ - type: Authentication url: authentication/matchpoint-therapeutics-authentication.yml - type: Conventions url: conventions/matchpoint-therapeutics-conventions.yml - type: Conformance url: conformance/matchpoint-therapeutics-conformance.yml - type: ErrorCatalog url: errors/matchpoint-therapeutics-problem-types.yml - type: Lifecycle url: lifecycle/matchpoint-therapeutics-lifecycle.yml - type: DataModel url: data-model/matchpoint-therapeutics-data-model.yml - type: Overlay url: overlays/matchpoint-therapeutics-content-overlay.yaml - type: DomainSecurity url: security/matchpoint-therapeutics-domain-security.yml - type: Packages url: packages/matchpoint-therapeutics-packages.yml - type: Plans url: plans/matchpoint-therapeutics-plans-pricing.yml - type: RateLimits url: rate-limits/matchpoint-therapeutics-rate-limits.yml - type: LLMsTxt url: llms/matchpoint-therapeutics-llms.txt - type: AgentSkill url: skills/_index.yml x-enrichment: date: '2026-08-25' status: enriched artifacts_added: 27 pass: local-v1