# Mission Bio

> Mission Bio is a South San Francisco single-cell multi-omics company. Its Tapestri Platform
> simultaneously resolves DNA variants, copy number, protein and RNA signal from the same individual
> cell for oncology, precision medicine, and cell-and-gene-therapy research. Mission Bio publishes NO
> public REST, GraphQL, MCP, A2A or event API. Its developer surface is a first-party Python analysis
> stack — Mosaic and friends — distributed as conda packages on the `missionbio` Anaconda channel,
> operating on the HDF5 `.h5` files produced by the Tapestri Pipeline.

## Developer surface

- [Tapestri Developer Tools](https://missionbio.github.io/): landing page for Mission Bio's open developer tooling
- [Mosaic documentation (v3.17.0)](https://missionbio.github.io/mosaic/): full API reference for the tertiary-analysis library
- [Getting started](https://missionbio.github.io/mosaic/manual/getting_started.html): `import missionbio.mosaic as ms` then `ms.load(h5path)`
- [Installation](https://missionbio.github.io/mosaic/manual/install.html): platform installers from the Tapestri Portal, or `conda create --name mosaic -c missionbio -c conda-forge "missionbio.tertiary"`
- [Data structure](https://missionbio.github.io/mosaic/manual/data_structure.html): the Tapestri `.h5` model — Sample/SampleGroup, Dna/Cnv/Protein/Rna/Ge assays, row_attrs/col_attrs/layers
- [Vignettes](https://missionbio.github.io/mosaic/manual/vignettes.html): worked Jupyter notebooks
- [Cohort analysis](https://missionbio.github.io/mosaic/manual/cohort.html)
- [Module index](https://missionbio.github.io/mosaic/py-modindex.html)
- [Release notes](https://missionbio.github.io/mosaic/manual/changelog.html)
- [GitHub organization](https://github.com/MissionBio)

## Packages (conda, `missionbio` channel)

- [missionbio.mosaic 3.17.0](https://anaconda.org/missionbio/missionbio.mosaic): tertiary analysis and visualization
- [missionbio.tertiary 3.8.1](https://anaconda.org/missionbio/missionbio.tertiary): full environment meta-package
- [missionbio.h5 5.18.0](https://anaconda.org/missionbio/missionbio.h5): read/write Tapestri `.h5` files
- [missionbio.demultiplex 6.8.0](https://anaconda.org/missionbio/missionbio.demultiplex): NSP, PACE, SPARC, DNA assignment
- [missionbio.plotting 1.8.2](https://anaconda.org/missionbio/missionbio.plotting): Heatmap, LinePlot, PhyloTree, Fishplot, BarGraph
- [missionbio.annotation 1.11.1](https://anaconda.org/missionbio/missionbio.annotation): variant annotation
- [missionbio.filter 3.7.0](https://anaconda.org/missionbio/missionbio.filter): variant and cell filtering
- [missionbio.config 1.2.2](https://anaconda.org/missionbio/missionbio.config): shared configuration
- [missionbio.cli 1.1.2](https://anaconda.org/missionbio/missionbio.cli): entry point for the `tapestri` CLI
- [compass 2.0.0](https://anaconda.org/missionbio/compass): COpy number and Mutations Phylogeny from Amplicon Single-cell Sequencing

## Source

- [MissionBio/mosaic](https://github.com/MissionBio/mosaic): docs and example datasets (GPL-3.0)
- [MissionBio/mosaic-jupyter](https://github.com/MissionBio/mosaic-jupyter): vignette notebooks
- [MissionBio/tools](https://github.com/MissionBio/tools): BarcodeExtractor and barcode scripts
- [MissionBio/compass](https://github.com/MissionBio/compass): COMPASS

## Products and platform

- [Tapestri Platform](https://www.missionbio.com/products/platform)
- [Panels](https://www.missionbio.com/products/panels)
- [Assay Services](https://www.missionbio.com/products/assay-services)
- [Tapestri Portal](https://portal.missionbio.com/) — software downloads and data management (login required)
- [Tapestri Pipeline](https://tapestripipeline.missionbio.com/) — cloud secondary analysis; ingests `.fastq.gz`/`.fq.gz` from local upload, Amazon S3, or Illumina BaseSpace via the Cloud Connector

## Company

- [Website](https://www.missionbio.com/)
- [Blog](https://www.missionbio.com/company/blog)
- [Newsroom](https://www.missionbio.com/company/newsroom)
- [Resources / Learning Center](https://www.missionbio.com/resources/learning-center/)
- [Support Center](https://support.missionbio.com/hc/en-us) — customer-gated (403 to anonymous clients)
- [Contact](https://www.missionbio.com/company/contact) — info@missionbio.com, sales@missionbio.com, support@missionbio.com
- [Terms of Use](https://www.missionbio.com/legal/terms-of-use)
- [Privacy Policy](https://www.missionbio.com/legal/privacy-policy)

## What is NOT published (verified 2026-08-01)

- No OpenAPI/Swagger at any host root or docs host (`/openapi.json`, `/openapi.yaml`, `/swagger.json`, `/v1/openapi.json`, `/api-docs` all miss; `portal.missionbio.com` returns an SPA HTML shell with HTTP 200 for every path — not a spec)
- No GraphQL endpoint, no hosted MCP server, no A2A agent card at `/.well-known/agent-card.json` or `/.well-known/agent.json`
- No `/.well-known/` document of any kind (no security.txt, no OIDC discovery, no api-catalog)
- No AsyncAPI, no documented webhooks, no status page, no published SLA or deprecation policy
- No published Postman collection, no PyPI/npm distribution, no compliance certifications page

## API Evangelist artifacts in this repo

- packages/mission-bio-packages.yml
- cli/mission-bio-cli.yml
- changelog/mission-bio-changelog.yml
- lifecycle/mission-bio-lifecycle.yml
- data-model/mission-bio-data-model.yml
- conformance/mission-bio-conformance.yml
- security/mission-bio-domain-security.yml
- well-known/mission-bio-well-known.yml
- apis.yml — https://raw.githubusercontent.com/api-evangelist/mission-bio/refs/heads/main/apis.yml