aid: nuprobe
name: NuProbe
description: >-
  NuProbe is a genomics and molecular diagnostics company founded in 2016 on technology licensed
  from the Wyss Institute at Harvard University and Rice University, with headquarters in Shanghai,
  China and a US subsidiary, NuProbe USA, in Houston, Texas. Its two core chemistries are Blocker
  Displacement Amplification (BDA), which enriches low-frequency DNA variants ahead of sequencing or
  PCR, and Quantitative Amplicon Sequencing (QASeq), a UMI-based multiplexed amplicon method for the
  simultaneous ultrasensitive detection of mutations and copy number variations from FFPE tissue,
  fresh or frozen tissue and cell-free DNA. The company sells research-use assay panels for oncology
  and reproductive health, custom assay development, and biopharma services, and has licensed or
  co-developed its chemistry with Bio-Rad, Oxford Nanopore, QIAGEN, Illumina and Bionano. NuProbe is
  an assay and reagent company: its bioinformatics and primer-design algorithms are delivered inside
  its products and services rather than as a public developer platform, and it publishes no API,
  SDK, developer portal or machine-readable specification of any kind.
url: https://raw.githubusercontent.com/api-evangelist/nuprobe/refs/heads/main/apis.yml
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: false
  label: Hosted service · you call their endpoint
  confidence: medium
  source:
  - pricing
  generated: '2026-08-28'
  method: derived
image: https://nuprobe.com/wp-content/uploads/2021/04/NuProbe-PMS-Logo_for-website.png
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enrichment-pass
specificationVersion: '0.20'
created: '2026-08-26'
modified: '2026-08-26'
tags:
- Company
- Life Sciences
- Genomics
- Molecular Diagnostics
- Next-Generation Sequencing
- Oncology
- Biotechnology
- Precision Medicine
- Laboratory
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://nuprobe.com/
- type: Blog
  url: https://nuprobe.com/all-news/
- type: Support
  url: https://nuprobe.com/contact_us/
- type: PrivacyPolicy
  url: https://nuprobe.com/privacy-policy/
- type: TermsOfService
  url: https://nuprobe.com/nuprobe-usa-terms-and-conditions/
- type: DomainSecurity
  url: security/nuprobe-domain-security.yml
x-enrichment:
  date: '2026-08-26'
  status: minimal
  artifacts_added: 2
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: >-
    NuProbe sells BDA and QASeq molecular-diagnostics assay kits, custom assay development and
    biopharma lab services rather than software; 1,199 archived URLs for nuprobe.com contain no
    /developers, /docs, /api, swagger, openapi or graphql path, both company GitHub organizations
    (NuProbeUSA, NuProbe-Bioinfo) hold zero public repositories, no nuprobe package exists on npm,
    PyPI, crates.io or RubyGems, and the marketing site itself is additionally returning a
    Cloudflare 526 origin error on every path during this pass.
  evidence:
  - url: https://nuprobe.com/openapi.json
    status: 526
  - url: https://nuprobe.com/.well-known/api-catalog
    status: 526
  - url: http://web.archive.org/cdx/search/cdx?url=nuprobe.com*&output=text&fl=original,statuscode&collapse=urlkey&limit=3000
    status: 200
  - url: https://api.github.com/orgs/NuProbeUSA/repos
    status: 200
  - url: https://registry.npmjs.org/-/v1/search?text=nuprobe
    status: 200
  checked: '2026-08-26'