aid: quralis
name: QurAlis
image: https://www.quralis.com/wp-content/uploads/2024/04/Quralis_Square_ogThumbnail_Royal_Blue_RGB.png
description: >-
  QurAlis Corporation is a clinical-stage biotechnology company founded on December 12, 2016 in
  Cambridge, Massachusetts by Drs. Kasper Roet, Kevin Eggan and Clifford Woolf together with Q-State
  Biosciences, and staffed by neurodegenerative biologists out of Harvard Medical School and Harvard
  University. The company develops precision medicines for amyotrophic lateral sclerosis (ALS),
  frontotemporal dementia (FTD) and other neurodegenerative and neurological diseases, built on the
  discovery — published in Nature Neuroscience by co-founder Kevin Eggan's lab — that loss of normal
  TDP-43 function drives a decrease in STATHMIN-2 (STMN2) expression and impairs neuronal repair. Its
  lead candidates are QRL-201, a first-in-class molecule intended to restore STMN2 expression in ALS
  (ANQUR trial), and QRL-101, a potentially best-in-class selective Kv7.2/7.3 ion channel opener for
  hyperexcitability-induced disease progression in ALS as well as epilepsy and pain; a third program
  targets UNC13A cryptic-exon mis-splicing. Therapies are built on the proprietary FlexASO®
  anti-sense oligonucleotide splice-modulator platform. QurAlis publishes a corporate site covering
  its story, pipeline, platform, people, patient resources, presentations and press releases, but
  runs no developer program: no API documentation, no SDKs, no developer portal, no GitHub
  organisation and no machine-readable API contract of any kind.
url: https://raw.githubusercontent.com/api-evangelist/quralis/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.23'
created: '2026-08-05'
modified: '2026-08-05'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Life Sciences
- Neurology
- Neurodegenerative Disease
- ALS
- Precision Medicine
- Clinical Trials
- Drug Development
- Healthcare
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://www.quralis.com/
- type: About
  url: https://www.quralis.com/our-story/
- type: Pipeline
  url: https://www.quralis.com/pipeline/
- type: Platform
  url: https://www.quralis.com/platforms/
- type: Team
  url: https://www.quralis.com/people/
- type: Careers
  url: https://www.quralis.com/culture/
- type: Patients
  url: https://www.quralis.com/patients/
- type: Publications
  url: https://www.quralis.com/presentations-and-publications/
- type: News
  url: https://www.quralis.com/news/
- type: Blog
  url: https://www.quralis.com/news/
- type: Support
  url: https://www.quralis.com/contact/
- type: PrivacyPolicy
  url: https://www.quralis.com/privacy-policy/
- type: TermsOfService
  url: https://www.quralis.com/terms-of-use/
- type: LinkedIn
  url: https://www.linkedin.com/company/quralis1/
- type: Twitter
  url: https://twitter.com/QurAlisCo
- type: SecondaryMarket
  url: https://forgeglobal.com/quralis_stock/
- type: DomainSecurity
  url: security/quralis-domain-security.yml
- type: WellKnown
  url: well-known/quralis-well-known.yml
- type: LLMsTxt
  url: llms/quralis-llms.txt
x-enrichment:
  date: '2026-08-05'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: >-
    QurAlis is a clinical-stage biopharmaceutical company whose product is a drug pipeline, not
    software — no api., developer., docs., portal. or data. host resolves for quralis.com, no
    quralis GitHub organisation or npm/PyPI package exists, and every /.well-known/ and spec path on
    www.quralis.com returns a clean 404, leaving only the marketing site's WordPress /wp-json/ CMS
    routes whose bundled MCP and Abilities endpoints answer anonymous callers with 401
    rest_forbidden.
  evidence:
  - url: https://www.quralis.com/openapi.json
    status: 404
  - url: https://www.quralis.com/.well-known/agent-card.json
    status: 404
  - url: https://www.quralis.com/llms.txt
    status: 404
  - url: https://www.quralis.com/wp-json/mcp/mcp-adapter-default-server
    status: 401
  - url: https://api.github.com/orgs/quralis
    status: 404
  checked: '2026-08-05'