aid: ratio-therapeutics
name: Ratio Therapeutics
description: >-
  Ratio Therapeutics Inc. is a clinical-stage pharmaceutical company headquartered at One Design Center
  Place in Boston, Massachusetts, developing next-generation precision radiopharmaceuticals for solid
  tumors. Founded in 2022 by Jack Hoppin, Ph.D. and John Babich, Ph.D., the company pairs two proprietary
  R&D platforms — Trillium, a tunable albumin-binding targeting scaffold that modulates pharmacokinetics,
  and Macropa, a bifunctional chelator built for the alpha emitter actinium-225 — to improve drug
  availability, tumor delivery and tumor loading. Its lead program, [Ac-225]RTX-2358, is a FAP-targeted
  radiotherapeutic in the ATLAS Phase 1/2 trial, alongside a next-generation GRPR program, mono- and
  bispecific radioligand therapies, and PET imaging assets. Ratio has licensing and collaboration
  agreements with Novartis, Merck, Bayer and Lantheus, isotope supply agreements with Nusano, TerraPower
  Isotopes and PanTera, and manufacturing partnerships with PharmaLogic and Eckert & Ziegler. It closed a
  $70 million Series C in July 2026, bringing total capital raised past $240 million. Ratio is a
  therapeutics developer rather than a software vendor: it publishes no developer program, no public API
  and no machine-readable API contract.
url: https://raw.githubusercontent.com/api-evangelist/ratio-therapeutics/refs/heads/main/apis.yml
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
image: https://i0.wp.com/ratiotx.com/wp-content/uploads/2023/03/ratiologo_clr_sansblock.jpg?fit=1325%2C588&ssl=1
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.20'
created: '2026-08-26'
modified: '2026-08-26'
tags:
- Company
- Biotechnology
- Pharmaceuticals
- Life Sciences
- Healthcare
- Oncology
- Radiopharmaceuticals
- Drug Discovery
- Clinical Trials
- Precision Medicine
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/ratio-therapeutics-domain-security.yml
- type: Website
  url: https://ratiotx.com/
- type: Blog
  url: https://ratiotx.com/blog/
- type: News
  url: https://ratiotx.com/news/
- type: Support
  url: https://ratiotx.com/contact-us/
- type: Careers
  url: https://ratiotx.com/careers/
- type: GitHubOrganization
  url: https://github.com/ratiotx
- type: LinkedIn
  url: https://www.linkedin.com/company/ratio-therapeutics/
- type: LLMsTxt
  url: llms/ratio-therapeutics-llms.txt
x-enrichment:
  date: '2026-08-26'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: >-
    Ratio Therapeutics is a clinical-stage radiopharmaceutical developer whose product is a drug
    pipeline ([Ac-225]RTX-2358 and the Trillium/Macropa platforms); ratiotx.com is a twenty-page
    WordPress.com marketing site where every contract-discovery path — /openapi.json, /swagger.json,
    /v1/openapi.json, /api-docs, /docs, /redoc, /graphql — returns the theme's 404, the company's
    GitHub organization at github.com/ratiotx has zero public repositories, and the only
    machine-readable surface is the CMS's default, undocumented /wp-json/ endpoint rather than a
    product API.
  evidence:
  - url: https://ratiotx.com/
    status: 200
  - url: https://ratiotx.com/openapi.json
    status: 404
  - url: https://ratiotx.com/swagger.json
    status: 404
  - url: https://ratiotx.com/api-docs
    status: 404
  - url: https://ratiotx.com/graphql
    status: 404
  - url: https://ratiotx.com/.well-known/api-catalog
    status: 404
  - url: https://ratiotx.com/.well-known/agent-card.json
    status: 404
  - url: https://ratiotx.com/.well-known/agent.json
    status: 404
  - url: https://ratiotx.com/llms.txt
    status: 200
  - url: https://ratiotx.com/wp-json
    status: 200
  - url: https://github.com/ratiotx
    status: 200
  checked: '2026-08-26'