{ "description": "Example drug target record representing a genetically validated target identified through RGC exome data", "target": { "targetId": "tgt-pcsk9", "name": "PCSK9", "targetType": "Protein", "geneSymbol": "PCSK9", "uniprotId": "Q8NBP7", "biologicalFunction": "Proprotein convertase that cleaves LDL receptor on hepatocytes, reducing LDL clearance from blood", "diseaseArea": [ "Cardiovascular Disease", "Hypercholesterolemia", "Atherosclerosis" ], "modality": "Antibody", "geneticValidation": true, "rgcEvidence": true } }