aid: relay-tx name: Relay Therapeutics description: >- Relay Therapeutics is a Cambridge, Massachusetts clinical-stage precision medicines company (NASDAQ: RLAY) using protein motion to drug historically intractable oncology and genetic-disease targets. Its Dynamo platform combines full-length protein engineering, cryo-EM, ambient-temperature X-ray crystallography, long-timescale molecular dynamics, machine learning, virtual screening, activity- and ligand-based screening, and an ML-powered DNA-encoded library (REL-DEL) to design molecules against conformational states that static structures miss. The clinical pipeline is led by zovegalisib (RLY-2608), described as the first allosteric, pan-mutant, isoform-selective PI3K-alpha inhibitor, in Phase 3 for HR+/HER2- breast cancer and Phase 1/2 for vascular anomalies and PROS; RLY-8161, an NRAS- selective inhibitor, is in Phase 1/2 for NRAS-mutant solid tumors; an alpha-galactosidase A non-inhibitory chaperone for Fabry disease is in discovery; lirafugratinib (RLY-4008, FGFR2) was out-licensed to Elevar Therapeutics in December 2024. Relay has no public developer API, SDK, or open-source release; the Dynamo platform is proprietary internal R&D tooling, and the company's GitHub organization currently has no public repositories. The commercial surface is therapeutic candidates, clinical partnerships, and out-licensing rather than data products. type: Index position: Provider access: 3rd-Party image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg tags: - Drug Discovery - Precision Medicine - Oncology - Genetic Disease - Protein Motion - Computational Chemistry - Molecular Dynamics - Cryo-EM - Machine Learning - DNA-Encoded Libraries - Allosteric Inhibitors - PI3K-Alpha - NRAS - FGFR2 - Fabry Disease - Biotechnology - Clinical Stage url: https://raw.githubusercontent.com/api-evangelist/relay-tx/refs/heads/main/apis.yml created: '2026-05-24' modified: '2026-05-24' specificationVersion: '0.20' apis: [] common: - type: DomainSecurity url: security/relay-tx-domain-security.yml - type: Website url: https://relaytx.com - type: Science url: https://relaytx.com/science/ - type: DynamoPlatform url: https://relaytx.com/dynamo-platform/ - type: Pipeline url: https://relaytx.com/pipeline/ - type: Publications url: https://relaytx.com/publications/ - type: Patients url: https://relaytx.com/patients/ - type: Careers url: https://relaytx.com/careers/ - type: Contact url: https://relaytx.com/contact/ - type: InvestorRelations url: https://ir.relaytx.com - type: GitHub url: https://github.com/relaytx - type: LinkedIn url: https://www.linkedin.com/company/relay-therapeutics/ - type: Twitter url: https://twitter.com/relaytx maintainers: - FN: Kin Lane email: kin@apievangelist.com