aid: sherlock-biosciences
name: Sherlock Biosciences
description: >-
  Sherlock Biosciences is a molecular diagnostics company founded in 2019 out of the Broad Institute to
  commercialize SHERLOCK (Specific High-sensitivity Enzymatic Reporter unLOCKing), the CRISPR-based
  nucleic-acid detection method developed in the Zhang lab, alongside INSPECTR, an ambient-temperature
  synthetic-biology amplification platform. In May 2020 it received the first FDA Emergency Use
  Authorization ever granted to a CRISPR-based diagnostic, for SARS-CoV-2. The company developed
  disposable, instrument-free molecular self-tests, led by a combined Chlamydia trachomatis and Neisseria
  gonorrhoeae assay. OraSure Technologies acquired Sherlock Biosciences in December 2024 and absorbed it
  into its rapid-diagnostics portfolio; the sherlock.bio domain now permanently redirects to orasure.com.
  Sherlock Biosciences is a laboratory diagnostics developer and has never operated a public developer
  program, HTTP API, or machine-readable API contract.
url: https://raw.githubusercontent.com/api-evangelist/sherlock-biosciences/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
deliveryModel:
  model: library
  open_source: false
  commercial: false
  callable_host: false
  label: Library · distributed through package registries, no callable service
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
specificationVersion: '0.20'
created: '2026-08-27'
modified: '2026-08-27'
tags:
- Diagnostics
- Molecular Diagnostics
- CRISPR
- Biotechnology
- Life Sciences
- Healthcare
- Infectious Disease
- Point of Care Testing
- Synthetic Biology
- Bioinformatics
- Acquired
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/sherlock-biosciences-domain-security.yml
- type: Website
  url: https://sherlock.bio/
- type: ParentCompany
  url: https://orasure.com/
- type: GitHubOrganization
  url: https://github.com/SherlockBiosciences
- type: Packages
  url: packages/sherlock-biosciences-packages.yml
- type: LLMsTxt
  url: llms/sherlock-biosciences-llms.txt
x-enrichment:
  date: '2026-08-27'
  status: minimal
  artifacts_added: 4
  pass: local-v1
x-coverage:
  state: none
  reason: defunct
  detail: >-
    Sherlock Biosciences was acquired by OraSure Technologies in December 2024 and fully
    absorbed; its own domain sherlock.bio now returns a bare 301 to orasure.com, and every
    contract-discovery and .well-known path probed on sherlock.bio, orasure.com and
    www.orasure.com returned 404, leaving a molecular-diagnostics company that never ran a
    developer program with no surviving API surface of any kind.
  evidence:
  - url: https://sherlock.bio/
    status: 301
  - url: https://sherlock.bio/openapi.json
    status: 404
  - url: https://sherlock.bio/.well-known/agent-card.json
    status: 404
  - url: https://orasure.com/openapi.json
    status: 404
  - url: https://www.orasure.com/.well-known/api-catalog
    status: 404
  - url: https://github.com/SherlockBiosciences
    status: 200
  checked: '2026-08-27'