# SonoThera

> SonoThera, Inc. is a clinical-stage biotechnology company in South San Francisco, California,
> founded in 2022, developing nonviral genetic medicines delivered by externally applied
> ultrasound. SonoThera publishes no API, SDK or machine-readable specification.

## What SonoThera does

SonoThera's RIPPLE platform delivers nucleic-acid payloads without a viral vector. A lipid-and-
microbubble formulation is administered intravenously, and a diagnostic ultrasound probe is applied
over the target organ; the acoustic energy transiently permeabilizes cell membranes so the payload
enters cells only where the probe is aimed. A companion payload engineering platform, PORE, carries
DNA and RNA constructs, gene editing and gene silencing cargo across a range of sizes and formats.
The company holds an exclusive license to GE HealthCare's Optison and Sonazoid microbubble products
for use with the platform.

Lead programs target Duchenne muscular dystrophy (DMD) and autosomal dominant polycystic kidney
disease (ADPKD), with preclinical work in Alport syndrome and hemophilia A. Funding to date is
approximately $186 million: a $60.75 million Series A and an oversubscribed $125 million Series B,
from ARCH Venture Partners, Johnson & Johnson, Illumina Ventures and Eli Lilly. Co-founders are
Kenneth Greenberg (CEO), Steve Feinstein (Chief Scientific Officer) and Michael H. Davidson
(Executive Chairman).

## API surface

SonoThera has no developer program and no public API.

- No OpenAPI, Swagger, GraphQL, AsyncAPI, gRPC/Protobuf or WSDL contract is published on any
  SonoThera host.
- No /.well-known document is served: security.txt, openid-configuration,
  oauth-authorization-server, api-catalog, ai-plugin.json, agent-card.json and agent.json all
  return 404 on sonothera.com.
- No MCP server, no A2A agent card, no llms.txt of the company's own.
- No GitHub organization (api.github.com/orgs/sonothera returns 404) and no first-party package
  on npm, PyPI, RubyGems, crates.io, NuGet, Maven Central or pkg.go.dev.
- api., dev., docs., developer. and mcp..sonothera.com are all NXDOMAIN.

This file was generated by the API Evangelist enrichment pipeline from the company's public site,
not published by SonoThera.

## Public pages

- [Website](https://sonothera.com/): company home.
- [About](https://sonothera.com/about-us/): platform, leadership and investors.
- [Science](https://sonothera.com/science/): the RIPPLE and PORE platforms and preclinical data.
- [Patients](https://sonothera.com/patients/): indication and patient-facing information.
- [News](https://sonothera.com/news/): press releases and company announcements.
- [Careers](https://sonothera.com/careers/): open roles.
- [Contact](https://sonothera.com/contact-us/): 201 Haskins Way, South San Francisco, CA 94080.
- [LinkedIn](https://www.linkedin.com/company/sonothera): company profile.

## Provenance

- generated: 2026-08-28
- method: generated
- source: apis.yml + live probes of sonothera.com (see well-known/sonothera-well-known.yml)