aid: syapse
name: Syapse
description: >-
  Syapse was a San Francisco precision-medicine software company, founded in 2008, that built a
  real-world evidence platform for community oncology. Its product integrated structured clinical
  data from health-system EHRs with genomic/NGS results to support molecular tumor boards, care
  coordination, quality improvement and life-sciences research, and it ran the Syapse Learning
  Health Network of community health systems alongside collaborations with Roche, Amgen and the
  US Department of Veterans Affairs. Syapse Holdings was acquired by N-Power Medicine in a
  stock-for-stock exchange that closed 2024-12-30 and was announced 2025-01-12; its network of
  1,000+ community oncologists, its data and technology stack, and its team were folded into
  N-Power Medicine's always-on community clinical-research model. The Syapse brand has since been
  fully retired: syapse.com now serves nothing but a 292-byte meta-refresh stub redirecting to
  npowermedicine.com, dated 2025-01-12. Syapse never published a public developer program, and no
  public API, OpenAPI/AsyncAPI/GraphQL contract, SDK or developer portal survives.
image: https://avatars.githubusercontent.com/u/1268822?v=4
url: https://raw.githubusercontent.com/api-evangelist/syapse/refs/heads/main/apis.yml
x-api-posture: no-product-api
x-api-posture-basis: observed
x-api-posture-note: "Syapse never published a public developer program, and no public API, OpenAPI/AsyncAPI/GraphQL contract, SDK or developer portal survives."
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
x-parent-company: n-power-medicine
specificationVersion: '0.20'
created: '2026-08-29'
modified: '2026-08-29'
tags:
- Company
- Healthcare
- Oncology
- Precision Medicine
- Real-World Evidence
- Clinical Research
- Health Data
- Life Sciences
- Acquired
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/syapse-domain-security.yml
- type: Website
  url: https://syapse.com/
- type: GitHubOrganization
  url: https://github.com/syapse
- type: Packages
  url: packages/syapse-packages.yml
x-enrichment:
  date: '2026-08-29'
  status: minimal
  artifacts_added: 3
  pass: local-v1
x-coverage:
  state: none
  reason: defunct
  detail: >-
    Syapse was fully absorbed into N-Power Medicine (stock-for-stock, closed 2024-12-30) and its
    entire web property was retired the same week: syapse.com and www.syapse.com now answer every
    path — including an invented control path — with the identical 292-byte HTML meta-refresh stub
    to npowermedicine.com, Last-Modified 2025-01-12, so there is no docs host, no API host and no
    contract left to read.
  evidence:
  - url: https://syapse.com/
    status: 200
  - url: https://syapse.com/this-path-does-not-exist-9f3a
    status: 200
  - url: https://syapse.com/openapi.json
    status: 200
  - url: https://www.syapse.com/.well-known/security.txt
    status: 200
  - url: https://www.npowermedicine.com/openapi.json
    status: 404
  checked: '2026-08-29'