# Upstream Bio

> Clinical-stage biotechnology company in Waltham, Massachusetts (Nasdaq: UPB, IPO October 2024)
> developing verekitug (UPB-101), described by the company as the only known antagonist in clinical
> development targeting the receptor for thymic stromal lymphopoietin (TSLP), for severe asthma,
> chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic obstructive pulmonary disease (COPD).

Upstream Bio is a therapeutics developer, not a software vendor. It publishes **no developer
program, no public API, no SDK, no OpenAPI/GraphQL/AsyncAPI contract, no MCP server and no agent
card**. This file is generated by API Evangelist from the company's public web surface so that an
agent asking "does Upstream Bio have an API?" gets a correct answer instead of a guess.

## Company

- [Homepage](https://upstreambio.com/): company overview and lead program.
- [About](https://upstreambio.com/about/): leadership and board of directors.
- [Science](https://upstreambio.com/science/): TSLP biology and recent publications.
- [Pipeline](https://upstreambio.com/pipeline/): verekitug development status by indication.
- [Patients](https://upstreambio.com/patients/): disease areas and clinical trial information.
- [Join Us](https://upstreambio.com/join-us/): careers.

## Investors

- [Investor Relations](https://investors.upstreambio.com/): hosted IR site on a separate subdomain.
- [News releases](https://investors.upstreambio.com/news-events/news-releases): press releases.
- [SEC filings](https://investors.upstreambio.com/financial-information/sec-filings)
- [Events](https://investors.upstreambio.com/news-events/events) and
  [presentations](https://investors.upstreambio.com/news-events/presentations)
- [Contact](https://investors.upstreambio.com/shareholder-services/contact-us) ·
  [Email alerts](https://investors.upstreambio.com/shareholder-services/email-alerts)

## Legal

- [Terms of Use](https://upstreambio.com/terms/)
- [Privacy Policy](https://upstreambio.com/privacy-policy/)
- [Privacy Notice for Clinical Study Participants](https://upstreambio.com/privacy-notice-for-clinical-study-participants/)
- [EEA Investigators and Site Personnel Notice](https://upstreambio.com/eea-investigators-and-site-personnel-notice/)
- [Data Privacy Framework Privacy Notice](https://upstreambio.com/data-privacy-framework-privacy-notice/)
- [Data Processing Addendum](https://upstreambio.com/upstream-bio-data-processing-addendum/)

## Machine-readable surfaces

There is no product API. The only machine-readable endpoints on the company's own hosts are the
defaults that ship with its content management system, not a published developer offering:

- [RSS feed](https://upstreambio.com/feed/) — WordPress feed of press-release posts.
- [Sitemap index](https://upstreambio.com/sitemap_index.xml) — Yoast-generated.
- WordPress REST API at `https://upstreambio.com/wp-json/` — the WordPress core route index
  (245 routes across `wp/v2` and plugin namespaces such as `yoast/v1`, `redirection/v1`,
  `wpe/cache-plugin/v1`). It is advertised only by the standard `<link rel="https://api.w.org/">`
  tag, is undocumented by the company, carries `X-Robots-Tag: noindex`, and exposes site content
  (21 posts, 14 pages) rather than any Upstream Bio product capability. Writes require a WordPress
  application password. API Evangelist does not record this as an Upstream Bio API.

## Not published

No `/llms.txt`, `/openapi.json`, `/swagger.json`, `/graphql`, `/.well-known/api-catalog`,
`/.well-known/security.txt`, `/.well-known/agent-card.json` or `/.well-known/agent.json` is served
on either `upstreambio.com` or `investors.upstreambio.com` — all probed 2026-09-02 and returned 404
(or an edge 403 on the investor host). No GitHub organization, npm, PyPI or other package-registry
presence was found.

## About this file

Generated: 2026-09-02 · Method: generated · Source: https://upstreambio.com/ and
https://investors.upstreambio.com/, probed directly. Maintained by
[API Evangelist](https://apievangelist.com) as an independent third-party profile. This is not
Upstream Bio's own file. Corrections: https://github.com/api-evangelist/upstream-bio