grabix - a wee tool for random access into BGZF files. ====================================================== ``grabix`` leverages the fantastic BGZF library in ``samtools`` to provide random access into text files that have been compressed with ``bgzip``. ``grabix`` creates it's own index (.gbi) of the bgzipped file. Once indexed, one can extract arbitrary lines from the file with the ``grab`` command. Or choose random lines with the, well, ``random`` command. There's a ton of room for improvement, but I needed something quickly in support of a side project. Here's a brief example using the ``simrep.chr1.bed`` file provided in the repository. # 1. compress the file with bgzip bgzip simrep.chr1.bed # 2. create a grabix index of the file. # creates simrep.chr1.bed.gbi grabix index simrep.chr1.bed.gz # 3. now, extract the 100th line in the file. grabix grab simrep.chr1.bed.gz 100 chr1 401285 401444 trf 218 # 4. extract the 100th through 110th lines in the file. grabix grab simrep.chr1.bed.gz 100 110 chr1 401285 401444 trf 218 chr1 401573 401748 trf 280 chr1 404661 404707 trf 92 chr1 406202 406274 trf 76 chr1 406227 406286 trf 77 chr1 406776 406819 trf 68 chr1 409821 409866 trf 51 chr1 409865 409900 trf 52 chr1 421245 421285 trf 64 chr1 422395 422435 trf 80 chr1 422560 422588 trf 56 You can also use ``grabix`` to extract random lines from the file # extract 10 randome lines from the file using reservoir sampling grabix random simrep.chr1.bed.gz 10 Is a gzipped file bgzipped? grabix check simrep.chr1.bed.gz