{ "cells": [ { "cell_type": "markdown", "metadata": {}, "source": [ "# E8. To be completed after lesson 22\n", "\n", "
" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## Exercise 8.1\n", "\n", "Why can't we use `scipy.optimize.least_squares()` on the Singer data for mRNA counts from smFISH experiments?\n", "\n", "
" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## Exercise 8.2\n", "\n", "In your mind, is there a fundamental difference between maximum likelihood estimation for variate-covariate models and the other parametric models we have encountered before?\n", "\n", "
" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## Exercise 8.3\n", "\n", "Write down any questions or points of confusion that you have." ] } ], "metadata": { "kernelspec": { "display_name": "Python 3 (ipykernel)", "language": "python", "name": "python3" }, "language_info": { "codemirror_mode": { "name": "ipython", "version": 3 }, "file_extension": ".py", "mimetype": "text/x-python", "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython3", "version": "3.9.13" } }, "nbformat": 4, "nbformat_minor": 4 }