components:
  schemas:
    AcmgRank-Input:
      properties:
        comment:
          title: Comment
          type: string
        criterias:
          items:
            $ref: '#/components/schemas/SeqVarCriteria'
          title: Criterias
          type: array
      required:
      - criterias
      - comment
      title: AcmgRank
      type: object
    AcmgRank-Output:
      properties:
        comment:
          title: Comment
          type: string
        criterias:
          items:
            $ref: '#/components/schemas/SeqVarCriteria'
          title: Criterias
          type: array
      required:
      - criterias
      - comment
      title: AcmgRank
      type: object
    AcmgSeqVarCreate-Input:
      properties:
        acmg_rank:
          $ref: '#/components/schemas/AcmgRank-Input'
        seqvar_name:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$
          title: Seqvar Name
          type: string
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
      required:
      - seqvar_name
      - acmg_rank
      title: AcmgSeqVarCreate
      type: object
    AcmgSeqVarCreate-Output:
      properties:
        acmg_rank:
          $ref: '#/components/schemas/AcmgRank-Output'
        seqvar_name:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$
          title: Seqvar Name
          type: string
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
      required:
      - seqvar_name
      - acmg_rank
      title: AcmgSeqVarCreate
      type: object
    AcmgSeqVarRead:
      properties:
        acmg_rank:
          $ref: '#/components/schemas/AcmgRank-Output'
        id:
          format: uuid
          title: Id
          type: string
        seqvar_name:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$
          title: Seqvar Name
          type: string
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
      required:
      - seqvar_name
      - acmg_rank
      - id
      title: AcmgSeqVarRead
      type: object
    AcmgSeqVarUpdate:
      properties:
        acmg_rank:
          $ref: '#/components/schemas/AcmgRank-Input'
        seqvar_name:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$
          title: Seqvar Name
          type: string
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
      required:
      - seqvar_name
      - acmg_rank
      title: AcmgSeqVarUpdate
      type: object
    AdminMessageRead:
      properties:
        active_start:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Active Start
        active_stop:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Active Stop
        enabled:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Enabled
        id:
          format: uuid
          title: Id
          type: string
        text:
          anyOf:
          - type: string
          - type: 'null'
          title: Text
        title:
          anyOf:
          - type: string
          - type: 'null'
          title: Title
      required:
      - id
      title: AdminMessageRead
      type: object
    AffectedStatus:
      enum:
      - 'yes'
      - 'no'
      - unknown
      - not provided
      - not applicable
      title: AffectedStatus
      type: string
    AlleleOrigin:
      enum:
      - germline
      - somatic
      - de novo
      - unknown
      - inherited
      - maternal
      - paternal
      - biparental
      - not applicable
      title: AlleleOrigin
      type: string
    Assembly:
      enum:
      - GRCh38
      - hg38
      - GRCh37
      - hg19
      - NCBI36
      - hg18
      title: Assembly
      type: string
    BatchProcessingStatus:
      enum:
      - In processing
      - Success
      - Error
      - Partial success
      title: BatchProcessingStatus
      type: string
    BatchReleaseStatus:
      enum:
      - Released
      - Partial released
      - Not released
      title: BatchReleaseStatus
      type: string
    BearerResponse:
      properties:
        access_token:
          title: Access Token
          type: string
        token_type:
          title: Token Type
          type: string
      required:
      - access_token
      - token_type
      title: BearerResponse
      type: object
    Body_auth_bearer_login_api_v1_auth_bearer_login_post:
      properties:
        client_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Client Id
        client_secret:
          anyOf:
          - type: string
          - type: 'null'
          title: Client Secret
        grant_type:
          anyOf:
          - pattern: password
            type: string
          - type: 'null'
          title: Grant Type
        password:
          title: Password
          type: string
        scope:
          default: ''
          title: Scope
          type: string
        username:
          title: Username
          type: string
      required:
      - username
      - password
      title: Body_auth_bearer_login_api_v1_auth_bearer_login_post
      type: object
    Body_auth_cookie_login_api_v1_auth_cookie_login_post:
      properties:
        client_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Client Id
        client_secret:
          anyOf:
          - type: string
          - type: 'null'
          title: Client Secret
        grant_type:
          anyOf:
          - pattern: password
            type: string
          - type: 'null'
          title: Grant Type
        password:
          title: Password
          type: string
        scope:
          default: ''
          title: Scope
          type: string
        username:
          title: Username
          type: string
      required:
      - username
      - password
      title: Body_auth_cookie_login_api_v1_auth_cookie_login_post
      type: object
    Body_verify_request_token_api_v1_auth_request_verify_token_post:
      properties:
        email:
          format: email
          title: Email
          type: string
      required:
      - email
      title: Body_verify_request_token_api_v1_auth_request_verify_token_post
      type: object
    Body_verify_verify_api_v1_auth_verify_post:
      properties:
        token:
          title: Token
          type: string
      required:
      - token
      title: Body_verify_verify_api_v1_auth_verify_post
      type: object
    BookmarkCreate:
      properties:
        obj_id:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$|^(DEL|DUP)-(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-(\d+)$|^HGNC:(\d+)$
          title: Obj Id
          type: string
        obj_type:
          $ref: '#/components/schemas/BookmarkTypes'
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
      required:
      - obj_type
      - obj_id
      title: BookmarkCreate
      type: object
    BookmarkRead:
      properties:
        id:
          format: uuid
          title: Id
          type: string
        obj_id:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$|^(DEL|DUP)-(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-(\d+)$|^HGNC:(\d+)$
          title: Obj Id
          type: string
        obj_type:
          $ref: '#/components/schemas/BookmarkTypes'
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
      required:
      - obj_type
      - obj_id
      - id
      title: BookmarkRead
      type: object
    BookmarkTypes:
      enum:
      - seqvar
      - strucvar
      - gene
      title: BookmarkTypes
      type: string
    CaseInfoCreate:
      properties:
        affected_family_members:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Affected Family Members
        age_of_onset_month:
          anyOf:
          - type: integer
          - type: 'null'
          title: Age Of Onset Month
        diseases:
          anyOf:
          - items:
              $ref: '#/components/schemas/DiseaseTerm'
            type: array
          - type: 'null'
          title: Diseases
        ethnicity:
          $ref: '#/components/schemas/Ethnicity'
          default: reev:unknown_ethnicity
        family_segregation:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Family Segregation
        hpo_terms:
          anyOf:
          - items:
              $ref: '#/components/schemas/HpoTerm'
            type: array
          - type: 'null'
          title: Hpo Terms
        inheritance:
          $ref: '#/components/schemas/Inheritance'
          default: reev:unknown_inheritance
        pseudonym:
          anyOf:
          - type: string
          - type: 'null'
          title: Pseudonym
        sex:
          $ref: '#/components/schemas/Sex'
          default: reev:unknown_sex
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
        zygosity:
          $ref: '#/components/schemas/Zygosity'
          default: reev:unknown_zygosity
      title: CaseInfoCreate
      type: object
    CaseInfoRead:
      properties:
        affected_family_members:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Affected Family Members
        age_of_onset_month:
          anyOf:
          - type: integer
          - type: 'null'
          title: Age Of Onset Month
        diseases:
          anyOf:
          - items:
              $ref: '#/components/schemas/DiseaseTerm'
            type: array
          - type: 'null'
          title: Diseases
        ethnicity:
          $ref: '#/components/schemas/Ethnicity'
          default: reev:unknown_ethnicity
        family_segregation:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Family Segregation
        hpo_terms:
          anyOf:
          - items:
              $ref: '#/components/schemas/HpoTerm'
            type: array
          - type: 'null'
          title: Hpo Terms
        id:
          format: uuid
          title: Id
          type: string
        inheritance:
          $ref: '#/components/schemas/Inheritance'
          default: reev:unknown_inheritance
        pseudonym:
          anyOf:
          - type: string
          - type: 'null'
          title: Pseudonym
        sex:
          $ref: '#/components/schemas/Sex'
          default: reev:unknown_sex
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
        zygosity:
          $ref: '#/components/schemas/Zygosity'
          default: reev:unknown_zygosity
      required:
      - id
      title: CaseInfoRead
      type: object
    CaseInfoUpdate:
      properties:
        affected_family_members:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Affected Family Members
        age_of_onset_month:
          anyOf:
          - type: integer
          - type: 'null'
          title: Age Of Onset Month
        diseases:
          anyOf:
          - items:
              $ref: '#/components/schemas/DiseaseTerm'
            type: array
          - type: 'null'
          title: Diseases
        ethnicity:
          $ref: '#/components/schemas/Ethnicity'
          default: reev:unknown_ethnicity
        family_segregation:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Family Segregation
        hpo_terms:
          anyOf:
          - items:
              $ref: '#/components/schemas/HpoTerm'
            type: array
          - type: 'null'
          title: Hpo Terms
        inheritance:
          $ref: '#/components/schemas/Inheritance'
          default: reev:unknown_inheritance
        pseudonym:
          anyOf:
          - type: string
          - type: 'null'
          title: Pseudonym
        sex:
          $ref: '#/components/schemas/Sex'
          default: reev:unknown_sex
        user:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: User
        zygosity:
          $ref: '#/components/schemas/Zygosity'
          default: reev:unknown_zygosity
      title: CaseInfoUpdate
      type: object
    Chromosome:
      enum:
      - '1'
      - '2'
      - '3'
      - '4'
      - '5'
      - '6'
      - '7'
      - '8'
      - '9'
      - '10'
      - '11'
      - '12'
      - '13'
      - '14'
      - '15'
      - '16'
      - '17'
      - '18'
      - '19'
      - '20'
      - '21'
      - '22'
      - X
      - Y
      - MT
      title: Chromosome
      type: string
    CitationDb:
      description: 'Allowed values for a citation''s `db` field.


        The values of the enumeration map to the values used by the ClinVar submission
        API.'
      enum:
      - PubMed
      - BookShelf
      - DOI
      - pmc
      title: CitationDb
      type: string
    ClinicalFeaturesAffectedStatus:
      enum:
      - present
      - absent
      - not tested
      title: ClinicalFeaturesAffectedStatus
      type: string
    ClinicalFeaturesDb:
      const: HP
      enum:
      - HP
      title: ClinicalFeaturesDb
      type: string
    ClinicalSignificanceDescription:
      description: 'Allowed values for the ``clinicalSignificanceDescription`` and

        ``germlineClassificationDescription``.


        The values of the enumeration map to the values used by the ClinVar submission
        API.'
      enum:
      - Pathogenic
      - Likely pathogenic
      - Uncertain significance
      - Likely benign
      - Benign
      - Pathogenic, low penetrance
      - Uncertain risk allele
      - Likely pathogenic, low penetrance
      - Established risk allele
      - Likely risk allele
      - affects
      - association
      - drug response
      - confers sensitivity
      - protective
      - other
      - not provided
      title: ClinicalSignificanceDescription
      type: string
    CollectionMethod:
      enum:
      - curation
      - literature only
      - reference population
      - provider interpretation
      - phenotyping only
      - case-control
      - clinical testing
      - in vitro
      - in vivo
      - research
      - not provided
      title: CollectionMethod
      type: string
    ConditionDb:
      enum:
      - OMIM
      - MedGen
      - Orphanet
      - MeSH
      - HP
      - MONDO
      title: ConditionDb
      type: string
    Created:
      properties:
        id:
          title: Id
          type: string
      required:
      - id
      title: Created
      type: object
    Criteria:
      enum:
      - PVS1
      - PS1
      - PS2
      - PS3
      - PS4
      - PM1
      - PM2
      - PM3
      - PM4
      - PM5
      - PM6
      - PP1
      - PP2
      - PP3
      - PP4
      - BA1
      - BS1
      - BS2
      - BS3
      - BS4
      - BP1
      - BP2
      - BP3
      - BP4
      - BP5
      - BP7
      title: Criteria
      type: string
    DiseaseTerm:
      properties:
        name:
          title: Name
          type: string
        omimId:
          title: Omimid
          type: string
      required:
      - omimId
      - name
      title: DiseaseTerm
      type: object
    ErrorCode:
      enum:
      - '0'
      - '1'
      - '2'
      title: ErrorCode
      type: string
    ErrorModel:
      properties:
        detail:
          anyOf:
          - type: string
          - additionalProperties:
              type: string
            type: object
          title: Detail
      required:
      - detail
      title: ErrorModel
      type: object
    Ethnicity:
      enum:
      - NCIT:C128937
      - NCIT:C17950
      - NCIT:C161419
      - NCIT:C43865
      - NCIT:C43851
      - NCIT:C17459
      - NCIT:C43866
      - NCIT:C41263
      - NCIT:C104495
      - reev:unknown_ethnicity
      title: Ethnicity
      type: string
    Evidence:
      enum:
      - Pathogenic Very Strong
      - Pathogenic Strong
      - Pathogenic Moderate
      - Pathogenic Supporting
      - Benign Standalone
      - Benign Strong
      - Benign Supporting
      - Not Set
      title: Evidence
      type: string
    GermlineClassification-Input:
      description: Details of somatic clinical impact classification.
      properties:
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        custom_classification_score:
          anyOf:
          - type: number
          - type: 'null'
          title: Custom Classification Score
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        explanation_of_drug_response:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Drug Response
        explanation_of_other_classification:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Other Classification
        germline_classification_description:
          $ref: '#/components/schemas/ClinicalSignificanceDescription'
        mode_of_inheritance:
          $ref: '#/components/schemas/ModeOfInheritance'
      required:
      - germline_classification_description
      - mode_of_inheritance
      title: GermlineClassification
      type: object
    GermlineClassification-Output:
      description: Details of somatic clinical impact classification.
      properties:
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        custom_classification_score:
          anyOf:
          - type: number
          - type: 'null'
          title: Custom Classification Score
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        explanation_of_drug_response:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Drug Response
        explanation_of_other_classification:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Other Classification
        germline_classification_description:
          $ref: '#/components/schemas/ClinicalSignificanceDescription'
        mode_of_inheritance:
          $ref: '#/components/schemas/ModeOfInheritance'
      required:
      - germline_classification_description
      - mode_of_inheritance
      title: GermlineClassification
      type: object
    HTTPValidationError:
      properties:
        detail:
          items:
            $ref: '#/components/schemas/ValidationError'
          title: Detail
          type: array
      title: HTTPValidationError
      type: object
    HpoTerm:
      properties:
        name:
          title: Name
          type: string
        termId:
          title: Termid
          type: string
      required:
      - termId
      - name
      title: HpoTerm
      type: object
    Inheritance:
      enum:
      - NCIT:C94245
      - NCIT:C94246
      - NCIT:C94599
      - NCIT:C93189
      - NCIT:C94542
      - NCIT:C94247
      - reev:unknown_inheritance
      title: Inheritance
      type: string
    ModeOfInheritance:
      enum:
      - Autosomal dominant inheritance
      - Autosomal recessive inheritance
      - Mitochondrial inheritance
      - Genetic anticipation
      - Sporadic
      - Sex-limited autosomal dominant
      - Somatic mutation
      - X-linked recessive inheritance
      - X-linked dominant inheritance
      - Y-linked inheritance
      - Other
      - X-linked inheritance
      - Codominant
      - Semidominant inheritance
      - Autosomal unknown
      - Autosomal dominant inheritance with maternal imprinting
      - Autosomal dominant inheritance with paternal imprinting
      - Multifactorial inheritance
      - Unknown mechanism
      - Oligogenic inheritance
      title: ModeOfInheritance
      type: string
    Msg:
      properties:
        msg:
          title: Msg
          type: string
      required:
      - msg
      title: Msg
      type: object
    MultipleConditionExplanation:
      enum:
      - Novel disease
      - Uncertain
      - Co-occurring
      title: MultipleConditionExplanation
      type: string
    OAuth2ProviderPublic:
      description: Information exposed via API.
      properties:
        label:
          title: Label
          type: string
        name:
          title: Name
          type: string
      required:
      - name
      - label
      title: OAuth2ProviderPublic
      type: object
    OncogenicityClassificationDescription:
      enum:
      - Oncogenic
      - Likely Oncogenic
      - - Uncertain significance
      - - Likely benign
      - Benign
      title: OncogenicityClassificationDescription
    Presence:
      enum:
      - Present
      - Absent
      - Unknown
      title: Presence
      type: string
    PresenceOfSomaticVariantInNormalTissue:
      enum:
      - present
      - absent
      - not tested
      title: PresenceOfSomaticVariantInNormalTissue
      type: string
    PublicOAuthAccount:
      description: Public part of OAuth account model.
      properties:
        account_email:
          title: Account Email
          type: string
        account_id:
          title: Account Id
          type: string
        id:
          title: Id
        oauth_name:
          title: Oauth Name
          type: string
      required:
      - id
      - oauth_name
      - account_id
      - account_email
      title: PublicOAuthAccount
      type: object
    RecordStatus:
      enum:
      - novel
      - update
      title: RecordStatus
      type: string
    ReleaseStatus:
      enum:
      - public
      - hold until published
      title: ReleaseStatus
      type: string
    ResponseMessage:
      description: 'A simple response message from ClinVar.


        This is used for storing the error messages from ClinVar.'
      properties:
        text:
          title: Text
          type: string
      required:
      - text
      title: ResponseMessage
      type: object
    RetrieveStatusResult-Input:
      description: Result type for ``retrieve_status`` function.
      properties:
        status:
          $ref: '#/components/schemas/SubmissionStatus-Input'
        summaries:
          additionalProperties:
            $ref: '#/components/schemas/SummaryResponse-Input'
          title: Summaries
          type: object
      required:
      - status
      - summaries
      title: RetrieveStatusResult
      type: object
    RetrieveStatusResult-Output:
      description: Result type for ``retrieve_status`` function.
      properties:
        status:
          $ref: '#/components/schemas/SubmissionStatus-Output'
        summaries:
          additionalProperties:
            $ref: '#/components/schemas/SummaryResponse-Output'
          title: Summaries
          type: object
      required:
      - status
      - summaries
      title: RetrieveStatusResult
      type: object
    SeqVarCriteria:
      properties:
        criteria:
          $ref: '#/components/schemas/Criteria'
        evidence:
          $ref: '#/components/schemas/Evidence'
        presence:
          $ref: '#/components/schemas/Presence'
        summary:
          anyOf:
          - type: string
          - type: 'null'
          title: Summary
      required:
      - criteria
      - presence
      - evidence
      title: SeqVarCriteria
      type: object
    Sex:
      enum:
      - PATO:0000384
      - PATO:0000383
      - reev:unknown_sex
      title: Sex
      type: string
    SomaticClinicalImpactAssertionType:
      enum:
      - 'therapeutic: sensitivity/response'
      - 'therapeutic: resistance'
      - 'therapeutic: reduced sensitivity'
      - 'diagnostic: supports diagnosis'
      - 'diagnostic: excludes diagnosis'
      - 'prognostic: better outcome'
      - 'prognostic: poor outcome'
      title: SomaticClinicalImpactAssertionType
      type: string
    SomaticClinicalImpactClassification-Input:
      description: Details of somatic clinical impact classification.
      properties:
        assertion_type_for_clinical_impact:
          anyOf:
          - $ref: '#/components/schemas/SomaticClinicalImpactAssertionType'
          - type: 'null'
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        clinical_impact_classification_description:
          $ref: '#/components/schemas/SomaticClinicalImpactClassificationDescription'
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        drug_for_therapeutic_assertion:
          anyOf:
          - type: string
          - type: 'null'
          title: Drug For Therapeutic Assertion
      required:
      - clinical_impact_classification_description
      title: SomaticClinicalImpactClassification
      type: object
    SomaticClinicalImpactClassification-Output:
      description: Details of somatic clinical impact classification.
      properties:
        assertion_type_for_clinical_impact:
          anyOf:
          - $ref: '#/components/schemas/SomaticClinicalImpactAssertionType'
          - type: 'null'
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        clinical_impact_classification_description:
          $ref: '#/components/schemas/SomaticClinicalImpactClassificationDescription'
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        drug_for_therapeutic_assertion:
          anyOf:
          - type: string
          - type: 'null'
          title: Drug For Therapeutic Assertion
      required:
      - clinical_impact_classification_description
      title: SomaticClinicalImpactClassification
      type: object
    SomaticClinicalImpactClassificationDescription:
      enum:
      - Tier I - Strong
      - Tier II - Potential
      - Tier III - Unknown
      - Tier IV - Benign/Likely benign
      title: SomaticClinicalImpactClassificationDescription
      type: string
    SomaticOncogenicityClassification-Input:
      description: Details of somatic clinical impact classification.
      properties:
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        oncogenicity_classification_description:
          $ref: '#/components/schemas/OncogenicityClassificationDescription'
      required:
      - oncogenicity_classification_description
      title: SomaticOncogenicityClassification
      type: object
    SomaticOncogenicityClassification-Output:
      description: Details of somatic clinical impact classification.
      properties:
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        oncogenicity_classification_description:
          $ref: '#/components/schemas/OncogenicityClassificationDescription'
      required:
      - oncogenicity_classification_description
      title: SomaticOncogenicityClassification
      type: object
    StructVarMethodType:
      enum:
      - SNP array
      - Oligo array
      - Read depth
      - Paired-end mapping
      - One end anchored assembly
      - Sequence alignment
      - Optical mapping
      - Curated,PCR
      title: StructVarMethodType
      type: string
    SubmissionActivityCreate:
      properties:
        kind:
          $ref: '#/components/schemas/SubmissionActivityKind'
        request_payload:
          anyOf:
          - $ref: '#/components/schemas/SubmissionContainer-Input'
          - type: 'null'
        request_timestamp:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Request Timestamp
        response_payload:
          anyOf:
          - $ref: '#/components/schemas/ResponseMessage'
          - $ref: '#/components/schemas/Created'
          - $ref: '#/components/schemas/RetrieveStatusResult-Input'
          - type: 'null'
          title: Response Payload
        response_timestamp:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Response Timestamp
        status:
          $ref: '#/components/schemas/SubmissionActivityStatus'
        submissionthread_id:
          format: uuid
          title: Submissionthread Id
          type: string
      required:
      - kind
      - status
      - submissionthread_id
      title: SubmissionActivityCreate
      type: object
    SubmissionActivityKind:
      description: Type of the :ref:`SubmissionActivity`.
      enum:
      - create
      - retrieve
      - update
      - delete
      title: SubmissionActivityKind
      type: string
    SubmissionActivityRead:
      properties:
        created:
          format: date-time
          title: Created
          type: string
        id:
          format: uuid
          title: Id
          type: string
        kind:
          $ref: '#/components/schemas/SubmissionActivityKind'
        request_payload:
          anyOf:
          - $ref: '#/components/schemas/SubmissionContainer-Output'
          - type: 'null'
        request_timestamp:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Request Timestamp
        response_payload:
          anyOf:
          - $ref: '#/components/schemas/ResponseMessage'
          - $ref: '#/components/schemas/Created'
          - $ref: '#/components/schemas/RetrieveStatusResult-Output'
          - type: 'null'
          title: Response Payload
        response_timestamp:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Response Timestamp
        status:
          $ref: '#/components/schemas/SubmissionActivityStatus'
        submissionthread_id:
          format: uuid
          title: Submissionthread Id
          type: string
      required:
      - kind
      - status
      - id
      - created
      - submissionthread_id
      title: SubmissionActivityRead
      type: object
    SubmissionActivityStatus:
      description: 'Status of a :ref:`SubmissionActivity`.


        An activity starts out waiting in the queue to be picked up by the

        worker, goes on into being processed, and ends up being complete

        or failed.  An activity can also end up being in a timeout state.'
      enum:
      - initial
      - waiting
      - in_progress
      - complete_success
      - complete_failure
      - complete_in_progress
      - failed
      - timeout
      title: SubmissionActivityStatus
      type: string
    SubmissionActivityUpdate:
      properties:
        kind:
          $ref: '#/components/schemas/SubmissionActivityKind'
        request_payload:
          anyOf:
          - $ref: '#/components/schemas/SubmissionContainer-Input'
          - type: 'null'
        request_timestamp:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Request Timestamp
        response_payload:
          anyOf:
          - $ref: '#/components/schemas/ResponseMessage'
          - $ref: '#/components/schemas/Created'
          - $ref: '#/components/schemas/RetrieveStatusResult-Input'
          - type: 'null'
          title: Response Payload
        response_timestamp:
          anyOf:
          - format: date-time
            type: string
          - type: 'null'
          title: Response Timestamp
        status:
          $ref: '#/components/schemas/SubmissionActivityStatus'
      required:
      - kind
      - status
      title: SubmissionActivityUpdate
      type: object
    SubmissionAssertionCriteria:
      properties:
        db:
          anyOf:
          - $ref: '#/components/schemas/CitationDb'
          - type: 'null'
        id:
          anyOf:
          - type: string
          - type: 'null'
          title: Id
        url:
          anyOf:
          - type: string
          - type: 'null'
          title: Url
      title: SubmissionAssertionCriteria
      type: object
    SubmissionChromosomeCoordinates:
      properties:
        accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Accession
        alternate_allele:
          anyOf:
          - type: string
          - type: 'null'
          title: Alternate Allele
        assembly:
          anyOf:
          - $ref: '#/components/schemas/Assembly'
          - type: 'null'
        chromosome:
          anyOf:
          - $ref: '#/components/schemas/Chromosome'
          - type: 'null'
        inner_start:
          anyOf:
          - type: integer
          - type: 'null'
          title: Inner Start
        inner_stop:
          anyOf:
          - type: integer
          - type: 'null'
          title: Inner Stop
        outer_start:
          anyOf:
          - type: integer
          - type: 'null'
          title: Outer Start
        outer_stop:
          anyOf:
          - type: integer
          - type: 'null'
          title: Outer Stop
        reference_allele:
          anyOf:
          - type: string
          - type: 'null'
          title: Reference Allele
        start:
          anyOf:
          - type: integer
          - type: 'null'
          title: Start
        stop:
          anyOf:
          - type: integer
          - type: 'null'
          title: Stop
        variant_length:
          anyOf:
          - type: integer
          - type: 'null'
          title: Variant Length
      title: SubmissionChromosomeCoordinates
      type: object
    SubmissionCitation:
      properties:
        db:
          anyOf:
          - $ref: '#/components/schemas/CitationDb'
          - type: 'null'
        id:
          anyOf:
          - type: string
          - type: 'null'
          title: Id
        url:
          anyOf:
          - type: string
          - type: 'null'
          title: Url
      title: SubmissionCitation
      type: object
    SubmissionClinicalFeature:
      properties:
        clinical_features_affected_status:
          $ref: '#/components/schemas/ClinicalFeaturesAffectedStatus'
        db:
          anyOf:
          - $ref: '#/components/schemas/ClinicalFeaturesDb'
          - type: 'null'
        id:
          anyOf:
          - type: string
          - type: 'null'
          title: Id
        name:
          anyOf:
          - type: string
          - type: 'null'
          title: Name
      required:
      - clinical_features_affected_status
      title: SubmissionClinicalFeature
      type: object
    SubmissionClinicalImpactSubmission-Input:
      properties:
        clinical_impact_classification:
          $ref: '#/components/schemas/SomaticClinicalImpactClassification-Input'
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Input'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetSomatic-Input'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Input'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Input'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInSomatic-Input'
          title: Observed In
          type: array
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Input'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Input'
          - type: 'null'
      required:
      - record_status
      - clinical_impact_classification
      - condition_set
      - observed_in
      title: SubmissionClinicalImpactSubmission
      type: object
    SubmissionClinicalImpactSubmission-Output:
      properties:
        clinical_impact_classification:
          $ref: '#/components/schemas/SomaticClinicalImpactClassification-Output'
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Output'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetSomatic-Output'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Output'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Output'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInSomatic-Output'
          title: Observed In
          type: array
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Output'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Output'
          - type: 'null'
      required:
      - record_status
      - clinical_impact_classification
      - condition_set
      - observed_in
      title: SubmissionClinicalImpactSubmission
      type: object
    SubmissionClinicalSignificance-Input:
      properties:
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        clinical_significance_description:
          $ref: '#/components/schemas/ClinicalSignificanceDescription'
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        custom_assertion_score:
          anyOf:
          - type: number
          - type: 'null'
          title: Custom Assertion Score
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        explanation_of_drug_response:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Drug Response
        explanation_of_other_clinical_significance:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Other Clinical Significance
        mode_of_inheritance:
          anyOf:
          - $ref: '#/components/schemas/ModeOfInheritance'
          - type: 'null'
      required:
      - clinical_significance_description
      title: SubmissionClinicalSignificance
      type: object
    SubmissionClinicalSignificance-Output:
      properties:
        citation:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCitation'
            type: array
          - type: 'null'
          title: Citation
        clinical_significance_description:
          $ref: '#/components/schemas/ClinicalSignificanceDescription'
        comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Comment
        custom_assertion_score:
          anyOf:
          - type: number
          - type: 'null'
          title: Custom Assertion Score
        date_last_evaluated:
          anyOf:
          - type: string
          - type: 'null'
          title: Date Last Evaluated
        explanation_of_drug_response:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Drug Response
        explanation_of_other_clinical_significance:
          anyOf:
          - type: string
          - type: 'null'
          title: Explanation Of Other Clinical Significance
        mode_of_inheritance:
          anyOf:
          - $ref: '#/components/schemas/ModeOfInheritance'
          - type: 'null'
      required:
      - clinical_significance_description
      title: SubmissionClinicalSignificance
      type: object
    SubmissionClinvarDeletion:
      properties:
        accession_set:
          items:
            $ref: '#/components/schemas/SubmissionClinvarDeletionAccessionSet'
          title: Accession Set
          type: array
      required:
      - accession_set
      title: SubmissionClinvarDeletion
      type: object
    SubmissionClinvarDeletionAccessionSet:
      properties:
        accession:
          title: Accession
          type: string
        reason:
          anyOf:
          - type: string
          - type: 'null'
          title: Reason
      required:
      - accession
      title: SubmissionClinvarDeletionAccessionSet
      type: object
    SubmissionClinvarSubmission-Input:
      properties:
        clinical_significance:
          $ref: '#/components/schemas/SubmissionClinicalSignificance-Input'
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Input'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetGermline-Input'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Input'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Input'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInGermline-Input'
          title: Observed In
          type: array
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Input'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Input'
          - type: 'null'
      required:
      - record_status
      - clinical_significance
      - condition_set
      - observed_in
      title: SubmissionClinvarSubmission
      type: object
    SubmissionClinvarSubmission-Output:
      properties:
        clinical_significance:
          $ref: '#/components/schemas/SubmissionClinicalSignificance-Output'
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Output'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetGermline-Output'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Output'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Output'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInGermline-Output'
          title: Observed In
          type: array
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Output'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Output'
          - type: 'null'
      required:
      - record_status
      - clinical_significance
      - condition_set
      - observed_in
      title: SubmissionClinvarSubmission
      type: object
    SubmissionCompoundHeterozygoteSet-Input:
      properties:
        hgvs:
          title: Hgvs
          type: string
        variant_sets:
          items:
            $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSetVariantSet-Input'
          title: Variant Sets
          type: array
      required:
      - hgvs
      - variant_sets
      title: SubmissionCompoundHeterozygoteSet
      type: object
    SubmissionCompoundHeterozygoteSet-Output:
      properties:
        hgvs:
          title: Hgvs
          type: string
        variant_sets:
          items:
            $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSetVariantSet-Output'
          title: Variant Sets
          type: array
      required:
      - hgvs
      - variant_sets
      title: SubmissionCompoundHeterozygoteSet
      type: object
    SubmissionCompoundHeterozygoteSetVariantSet-Input:
      properties:
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Input'
          - type: 'null'
      title: SubmissionCompoundHeterozygoteSetVariantSet
      type: object
    SubmissionCompoundHeterozygoteSetVariantSet-Output:
      properties:
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Output'
          - type: 'null'
      title: SubmissionCompoundHeterozygoteSetVariantSet
      type: object
    SubmissionCondition:
      properties:
        db:
          anyOf:
          - $ref: '#/components/schemas/ConditionDb'
          - type: 'null'
        id:
          anyOf:
          - type: string
          - type: 'null'
          title: Id
        name:
          anyOf:
          - type: string
          - type: 'null'
          title: Name
      title: SubmissionCondition
      type: object
    SubmissionConditionSetGermline-Input:
      properties:
        condition:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCondition'
            type: array
          - type: 'null'
          title: Condition
        drug_response:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionDrugResponse-Input'
            type: array
          - type: 'null'
          title: Drug Response
        multiple_condition_explanation:
          anyOf:
          - $ref: '#/components/schemas/MultipleConditionExplanation'
          - type: 'null'
      title: SubmissionConditionSetGermline
      type: object
    SubmissionConditionSetGermline-Output:
      properties:
        condition:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCondition'
            type: array
          - type: 'null'
          title: Condition
        drug_response:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionDrugResponse-Output'
            type: array
          - type: 'null'
          title: Drug Response
        multiple_condition_explanation:
          anyOf:
          - $ref: '#/components/schemas/MultipleConditionExplanation'
          - type: 'null'
      title: SubmissionConditionSetGermline
      type: object
    SubmissionConditionSetSomatic-Input:
      properties:
        condition:
          items:
            $ref: '#/components/schemas/SubmissionCondition'
          title: Condition
          type: array
        drug_response:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionDrugResponse-Input'
            type: array
          - type: 'null'
          title: Drug Response
        multiple_condition_explanation:
          anyOf:
          - $ref: '#/components/schemas/MultipleConditionExplanation'
          - type: 'null'
      required:
      - condition
      title: SubmissionConditionSetSomatic
      type: object
    SubmissionConditionSetSomatic-Output:
      properties:
        condition:
          items:
            $ref: '#/components/schemas/SubmissionCondition'
          title: Condition
          type: array
        drug_response:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionDrugResponse-Output'
            type: array
          - type: 'null'
          title: Drug Response
        multiple_condition_explanation:
          anyOf:
          - $ref: '#/components/schemas/MultipleConditionExplanation'
          - type: 'null'
      required:
      - condition
      title: SubmissionConditionSetSomatic
      type: object
    SubmissionContainer-Input:
      properties:
        assertion_criteria:
          anyOf:
          - $ref: '#/components/schemas/SubmissionAssertionCriteria'
          - type: 'null'
        behalf_org_id:
          anyOf:
          - type: integer
          - type: 'null'
          title: Behalf Org Id
        clinical_impact_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinicalImpactSubmission-Input'
            type: array
          - type: 'null'
          title: Clinical Impact Submission
        clinvar_deletion:
          anyOf:
          - $ref: '#/components/schemas/SubmissionClinvarDeletion'
          - type: 'null'
        clinvar_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinvarSubmission-Input'
            type: array
          - type: 'null'
          title: Clinvar Submission
        clinvar_submission_release_status:
          anyOf:
          - $ref: '#/components/schemas/ReleaseStatus'
          - type: 'null'
        germline_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionGermlineSubmission-Input'
            type: array
          - type: 'null'
          title: Germline Submission
        oncogenicity_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionOncogenicitySubmission-Input'
            type: array
          - type: 'null'
          title: Oncogenicity Submission
        submission_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Submission Name
      title: SubmissionContainer
      type: object
    SubmissionContainer-Output:
      properties:
        assertion_criteria:
          anyOf:
          - $ref: '#/components/schemas/SubmissionAssertionCriteria'
          - type: 'null'
        behalf_org_id:
          anyOf:
          - type: integer
          - type: 'null'
          title: Behalf Org Id
        clinical_impact_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinicalImpactSubmission-Output'
            type: array
          - type: 'null'
          title: Clinical Impact Submission
        clinvar_deletion:
          anyOf:
          - $ref: '#/components/schemas/SubmissionClinvarDeletion'
          - type: 'null'
        clinvar_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinvarSubmission-Output'
            type: array
          - type: 'null'
          title: Clinvar Submission
        clinvar_submission_release_status:
          anyOf:
          - $ref: '#/components/schemas/ReleaseStatus'
          - type: 'null'
        germline_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionGermlineSubmission-Output'
            type: array
          - type: 'null'
          title: Germline Submission
        oncogenicity_submission:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionOncogenicitySubmission-Output'
            type: array
          - type: 'null'
          title: Oncogenicity Submission
        submission_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Submission Name
      title: SubmissionContainer
      type: object
    SubmissionDiplotypeSet-Input:
      properties:
        haplotype_sets:
          items:
            $ref: '#/components/schemas/SubmissionHaplotypeSets-Input'
          title: Haplotype Sets
          type: array
        hgvs:
          title: Hgvs
          type: string
        star_allele_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Star Allele Name
      required:
      - haplotype_sets
      - hgvs
      title: SubmissionDiplotypeSet
      type: object
    SubmissionDiplotypeSet-Output:
      properties:
        haplotype_sets:
          items:
            $ref: '#/components/schemas/SubmissionHaplotypeSets-Output'
          title: Haplotype Sets
          type: array
        hgvs:
          title: Hgvs
          type: string
        star_allele_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Star Allele Name
      required:
      - haplotype_sets
      - hgvs
      title: SubmissionDiplotypeSet
      type: object
    SubmissionDistinctChromosomesSet-Input:
      properties:
        hgvs:
          title: Hgvs
          type: string
        variants:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Input'
          title: Variants
          type: array
      required:
      - hgvs
      - variants
      title: SubmissionDistinctChromosomesSet
      type: object
    SubmissionDistinctChromosomesSet-Output:
      properties:
        hgvs:
          title: Hgvs
          type: string
        variants:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Output'
          title: Variants
          type: array
      required:
      - hgvs
      - variants
      title: SubmissionDistinctChromosomesSet
      type: object
    SubmissionDrugResponse-Input:
      properties:
        condition:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCondition'
            type: array
          - type: 'null'
          title: Condition
        db:
          anyOf:
          - $ref: '#/components/schemas/ConditionDb'
          - type: 'null'
        drug_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Drug Name
        id:
          anyOf:
          - type: string
          - type: 'null'
          title: Id
      title: SubmissionDrugResponse
      type: object
    SubmissionDrugResponse-Output:
      properties:
        condition:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionCondition'
            type: array
          - type: 'null'
          title: Condition
        db:
          anyOf:
          - $ref: '#/components/schemas/ConditionDb'
          - type: 'null'
        drug_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Drug Name
        id:
          anyOf:
          - type: string
          - type: 'null'
          title: Id
      title: SubmissionDrugResponse
      type: object
    SubmissionGermlineSubmission-Input:
      properties:
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Input'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetGermline-Input'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Input'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Input'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        germline_classification:
          $ref: '#/components/schemas/GermlineClassification-Input'
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInGermline-Input'
          title: Observed In
          type: array
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Input'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Input'
          - type: 'null'
      required:
      - record_status
      - germline_classification
      - condition_set
      - observed_in
      title: SubmissionGermlineSubmission
      type: object
    SubmissionGermlineSubmission-Output:
      properties:
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Output'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetGermline-Output'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Output'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Output'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        germline_classification:
          $ref: '#/components/schemas/GermlineClassification-Output'
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInGermline-Output'
          title: Observed In
          type: array
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Output'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Output'
          - type: 'null'
      required:
      - record_status
      - germline_classification
      - condition_set
      - observed_in
      title: SubmissionGermlineSubmission
      type: object
    SubmissionHaplotypeSet-Input:
      properties:
        hgvs:
          title: Hgvs
          type: string
        star_allele_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Star Allele Name
        variants:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Input'
          title: Variants
          type: array
      required:
      - hgvs
      - variants
      title: SubmissionHaplotypeSet
      type: object
    SubmissionHaplotypeSet-Output:
      properties:
        hgvs:
          title: Hgvs
          type: string
        star_allele_name:
          anyOf:
          - type: string
          - type: 'null'
          title: Star Allele Name
        variants:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Output'
          title: Variants
          type: array
      required:
      - hgvs
      - variants
      title: SubmissionHaplotypeSet
      type: object
    SubmissionHaplotypeSets-Input:
      properties:
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
      title: SubmissionHaplotypeSets
      type: object
    SubmissionHaplotypeSets-Output:
      properties:
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
      title: SubmissionHaplotypeSets
      type: object
    SubmissionObservedInGermline-Input:
      properties:
        affected_status:
          $ref: '#/components/schemas/AffectedStatus'
        allele_origin:
          $ref: '#/components/schemas/AlleleOrigin'
        clinical_features:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinicalFeature'
            type: array
          - type: 'null'
          title: Clinical Features
        clinical_features_comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinical Features Comment
        collection_method:
          $ref: '#/components/schemas/CollectionMethod'
        number_of_individuals:
          anyOf:
          - type: integer
          - type: 'null'
          title: Number Of Individuals
        struct_var_method_type:
          anyOf:
          - $ref: '#/components/schemas/StructVarMethodType'
          - type: 'null'
      required:
      - affected_status
      - allele_origin
      - collection_method
      title: SubmissionObservedInGermline
      type: object
    SubmissionObservedInGermline-Output:
      properties:
        affected_status:
          $ref: '#/components/schemas/AffectedStatus'
        allele_origin:
          $ref: '#/components/schemas/AlleleOrigin'
        clinical_features:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinicalFeature'
            type: array
          - type: 'null'
          title: Clinical Features
        clinical_features_comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinical Features Comment
        collection_method:
          $ref: '#/components/schemas/CollectionMethod'
        number_of_individuals:
          anyOf:
          - type: integer
          - type: 'null'
          title: Number Of Individuals
        struct_var_method_type:
          anyOf:
          - $ref: '#/components/schemas/StructVarMethodType'
          - type: 'null'
      required:
      - affected_status
      - allele_origin
      - collection_method
      title: SubmissionObservedInGermline
      type: object
    SubmissionObservedInSomatic-Input:
      properties:
        affected_status:
          $ref: '#/components/schemas/AffectedStatus'
        allele_origin:
          $ref: '#/components/schemas/AlleleOrigin'
        clinical_features:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinicalFeature'
            type: array
          - type: 'null'
          title: Clinical Features
        clinical_features_comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinical Features Comment
        collection_method:
          $ref: '#/components/schemas/CollectionMethod'
        number_of_individuals:
          anyOf:
          - type: integer
          - type: 'null'
          title: Number Of Individuals
        presence_of_somatic_variant_in_normal_tissue:
          anyOf:
          - $ref: '#/components/schemas/PresenceOfSomaticVariantInNormalTissue'
          - type: 'null'
        somatic_variant_allele_fraction:
          anyOf:
          - type: number
          - type: 'null'
          title: Somatic Variant Allele Fraction
        struct_var_method_type:
          anyOf:
          - $ref: '#/components/schemas/StructVarMethodType'
          - type: 'null'
      required:
      - affected_status
      - allele_origin
      - collection_method
      title: SubmissionObservedInSomatic
      type: object
    SubmissionObservedInSomatic-Output:
      properties:
        affected_status:
          $ref: '#/components/schemas/AffectedStatus'
        allele_origin:
          $ref: '#/components/schemas/AlleleOrigin'
        clinical_features:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionClinicalFeature'
            type: array
          - type: 'null'
          title: Clinical Features
        clinical_features_comment:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinical Features Comment
        collection_method:
          $ref: '#/components/schemas/CollectionMethod'
        number_of_individuals:
          anyOf:
          - type: integer
          - type: 'null'
          title: Number Of Individuals
        presence_of_somatic_variant_in_normal_tissue:
          anyOf:
          - $ref: '#/components/schemas/PresenceOfSomaticVariantInNormalTissue'
          - type: 'null'
        somatic_variant_allele_fraction:
          anyOf:
          - type: number
          - type: 'null'
          title: Somatic Variant Allele Fraction
        struct_var_method_type:
          anyOf:
          - $ref: '#/components/schemas/StructVarMethodType'
          - type: 'null'
      required:
      - affected_status
      - allele_origin
      - collection_method
      title: SubmissionObservedInSomatic
      type: object
    SubmissionOncogenicitySubmission-Input:
      properties:
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Input'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetSomatic-Input'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Input'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Input'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Input'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInSomatic-Input'
          title: Observed In
          type: array
        oncogenicity_classification:
          $ref: '#/components/schemas/SomaticOncogenicityClassification-Input'
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Input'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Input'
          - type: 'null'
      required:
      - record_status
      - oncogenicity_classification
      - condition_set
      - observed_in
      title: SubmissionOncogenicitySubmission
      type: object
    SubmissionOncogenicitySubmission-Output:
      properties:
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        compound_heterozygote_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionCompoundHeterozygoteSet-Output'
          - type: 'null'
        condition_set:
          $ref: '#/components/schemas/SubmissionConditionSetSomatic-Output'
        diplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDiplotypeSet-Output'
          - type: 'null'
        distinct_chromosomes_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionDistinctChromosomesSet-Output'
          - type: 'null'
        extra_data:
          anyOf:
          - type: object
          - type: 'null'
          title: Extra Data
        haplotype_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        haplotype_single_variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionHaplotypeSet-Output'
          - type: 'null'
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
        observed_in:
          items:
            $ref: '#/components/schemas/SubmissionObservedInSomatic-Output'
          title: Observed In
          type: array
        oncogenicity_classification:
          $ref: '#/components/schemas/SomaticOncogenicityClassification-Output'
        phase_unknown_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionPhaseUnknownSet-Output'
          - type: 'null'
        record_status:
          $ref: '#/components/schemas/RecordStatus'
        variant_set:
          anyOf:
          - $ref: '#/components/schemas/SubmissionVariantSet-Output'
          - type: 'null'
      required:
      - record_status
      - oncogenicity_classification
      - condition_set
      - observed_in
      title: SubmissionOncogenicitySubmission
      type: object
    SubmissionPhaseUnknownSet-Input:
      properties:
        hgvs:
          title: Hgvs
          type: string
        variants:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Input'
          title: Variants
          type: array
      required:
      - hgvs
      - variants
      title: SubmissionPhaseUnknownSet
      type: object
    SubmissionPhaseUnknownSet-Output:
      properties:
        hgvs:
          title: Hgvs
          type: string
        variants:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Output'
          title: Variants
          type: array
      required:
      - hgvs
      - variants
      title: SubmissionPhaseUnknownSet
      type: object
    SubmissionStatus-Input:
      description: Internal submission status.
      properties:
        actions:
          items:
            $ref: '#/components/schemas/SubmissionStatusActions-Input'
          title: Actions
          type: array
      required:
      - actions
      title: SubmissionStatus
      type: object
    SubmissionStatus-Output:
      description: Internal submission status.
      properties:
        actions:
          items:
            $ref: '#/components/schemas/SubmissionStatusActions-Output'
          title: Actions
          type: array
      required:
      - actions
      title: SubmissionStatus
      type: object
    SubmissionStatusActions-Input:
      properties:
        id:
          title: Id
          type: string
        responses:
          items:
            $ref: '#/components/schemas/SubmissionStatusResponse-Input'
          title: Responses
          type: array
        status:
          title: Status
          type: string
        target_db:
          title: Target Db
          type: string
        updated:
          format: date-time
          title: Updated
          type: string
      required:
      - id
      - responses
      - status
      - target_db
      - updated
      title: SubmissionStatusActions
      type: object
    SubmissionStatusActions-Output:
      properties:
        id:
          title: Id
          type: string
        responses:
          items:
            $ref: '#/components/schemas/SubmissionStatusResponse-Output'
          title: Responses
          type: array
        status:
          title: Status
          type: string
        target_db:
          title: Target Db
          type: string
        updated:
          format: date-time
          title: Updated
          type: string
      required:
      - id
      - responses
      - status
      - target_db
      - updated
      title: SubmissionStatusActions
      type: object
    SubmissionStatusFile:
      properties:
        url:
          title: Url
          type: string
      required:
      - url
      title: SubmissionStatusFile
      type: object
    SubmissionStatusObject:
      properties:
        accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Accession
        content:
          $ref: '#/components/schemas/SubmissionStatusObjectContent'
        target_db:
          title: Target Db
          type: string
      required:
      - accession
      - content
      - target_db
      title: SubmissionStatusObject
      type: object
    SubmissionStatusObjectContent:
      properties:
        clinvar_processing_status:
          title: Clinvar Processing Status
          type: string
        clinvar_release_status:
          title: Clinvar Release Status
          type: string
      required:
      - clinvar_processing_status
      - clinvar_release_status
      title: SubmissionStatusObjectContent
      type: object
    SubmissionStatusResponse-Input:
      properties:
        files:
          items:
            $ref: '#/components/schemas/SubmissionStatusFile'
          title: Files
          type: array
        message:
          anyOf:
          - $ref: '#/components/schemas/SubmissionStatusResponseMessage'
          - type: 'null'
        objects:
          items:
            $ref: '#/components/schemas/SubmissionStatusObject'
          title: Objects
          type: array
        status:
          title: Status
          type: string
      required:
      - status
      - files
      - message
      - objects
      title: SubmissionStatusResponse
      type: object
    SubmissionStatusResponse-Output:
      properties:
        files:
          items:
            $ref: '#/components/schemas/SubmissionStatusFile'
          title: Files
          type: array
        message:
          anyOf:
          - $ref: '#/components/schemas/SubmissionStatusResponseMessage'
          - type: 'null'
        objects:
          items:
            $ref: '#/components/schemas/SubmissionStatusObject'
          title: Objects
          type: array
        status:
          title: Status
          type: string
      required:
      - status
      - files
      - message
      - objects
      title: SubmissionStatusResponse
      type: object
    SubmissionStatusResponseMessage:
      properties:
        error_code:
          anyOf:
          - $ref: '#/components/schemas/ErrorCode'
          - type: 'null'
        severity:
          title: Severity
          type: string
        text:
          title: Text
          type: string
      required:
      - error_code
      - severity
      - text
      title: SubmissionStatusResponseMessage
      type: object
    SubmissionThreadCreate:
      properties:
        desired_presence:
          $ref: '#/components/schemas/VariantPresence'
        effective_presence:
          anyOf:
          - $ref: '#/components/schemas/VariantPresence'
          - type: 'null'
        effective_scv:
          anyOf:
          - type: string
          - type: 'null'
          title: Effective Scv
        primary_variant_desc:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$|^(DEL|DUP)-(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-(\d+)$
          title: Primary Variant Desc
          type: string
        status:
          $ref: '#/components/schemas/SubmissionThreadStatus'
        submittingorg_id:
          format: uuid
          title: Submittingorg Id
          type: string
      required:
      - desired_presence
      - status
      - submittingorg_id
      - primary_variant_desc
      title: SubmissionThreadCreate
      type: object
    SubmissionThreadRead:
      properties:
        created:
          format: date-time
          title: Created
          type: string
        desired_presence:
          $ref: '#/components/schemas/VariantPresence'
        effective_presence:
          anyOf:
          - $ref: '#/components/schemas/VariantPresence'
          - type: 'null'
        effective_scv:
          anyOf:
          - type: string
          - type: 'null'
          title: Effective Scv
        id:
          format: uuid
          title: Id
          type: string
        primary_variant_desc:
          minLength: 1
          pattern: ^(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-([CGAT]+)-([CGAT]+)$|^(DEL|DUP)-(grch37|grch38)-([1-9]|1[0-9]|2[12]|X|Y|MT)-(\d+)-(\d+)$
          title: Primary Variant Desc
          type: string
        status:
          $ref: '#/components/schemas/SubmissionThreadStatus'
        submittingorg_id:
          format: uuid
          title: Submittingorg Id
          type: string
        updated:
          format: date-time
          title: Updated
          type: string
      required:
      - desired_presence
      - status
      - id
      - created
      - updated
      - submittingorg_id
      - primary_variant_desc
      title: SubmissionThreadRead
      type: object
    SubmissionThreadStatus:
      description: 'Status of a :ref:`SubmissionThread`.


        A thread starts out being in initial state while being edit by the

        user.  It is then submitted into the work queue together with an

        initial activity where it is waiting to be processed.  It is then

        worked on in the form of activities and ends up being complete or

        failed.  If the latest activity runs into a timeout (e.g., worker

        death) then this is reflected on the thread as well.'
      enum:
      - initial
      - waiting
      - in_progress
      - success
      - failed
      title: SubmissionThreadStatus
      type: string
    SubmissionThreadUpdate:
      properties:
        desired_presence:
          $ref: '#/components/schemas/VariantPresence'
        effective_presence:
          anyOf:
          - $ref: '#/components/schemas/VariantPresence'
          - type: 'null'
        effective_scv:
          anyOf:
          - type: string
          - type: 'null'
          title: Effective Scv
        status:
          $ref: '#/components/schemas/SubmissionThreadStatus'
      required:
      - desired_presence
      - status
      title: SubmissionThreadUpdate
      type: object
    SubmissionVariant-Input:
      properties:
        chromosome_coordinates:
          anyOf:
          - $ref: '#/components/schemas/SubmissionChromosomeCoordinates'
          - type: 'null'
        copy_number:
          anyOf:
          - type: string
          - type: 'null'
          title: Copy Number
        gene:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionVariantGene'
            type: array
          - type: 'null'
          title: Gene
        hgvs:
          anyOf:
          - type: string
          - type: 'null'
          title: Hgvs
        reference_copy_number:
          anyOf:
          - type: integer
          - type: 'null'
          title: Reference Copy Number
        variant_type:
          anyOf:
          - $ref: '#/components/schemas/VariantType'
          - type: 'null'
      title: SubmissionVariant
      type: object
    SubmissionVariant-Output:
      properties:
        chromosome_coordinates:
          anyOf:
          - $ref: '#/components/schemas/SubmissionChromosomeCoordinates'
          - type: 'null'
        copy_number:
          anyOf:
          - type: string
          - type: 'null'
          title: Copy Number
        gene:
          anyOf:
          - items:
              $ref: '#/components/schemas/SubmissionVariantGene'
            type: array
          - type: 'null'
          title: Gene
        hgvs:
          anyOf:
          - type: string
          - type: 'null'
          title: Hgvs
        reference_copy_number:
          anyOf:
          - type: integer
          - type: 'null'
          title: Reference Copy Number
        variant_type:
          anyOf:
          - $ref: '#/components/schemas/VariantType'
          - type: 'null'
      title: SubmissionVariant
      type: object
    SubmissionVariantGene:
      properties:
        id:
          anyOf:
          - type: integer
          - type: 'null'
          title: Id
        symbol:
          anyOf:
          - type: string
          - type: 'null'
          title: Symbol
      title: SubmissionVariantGene
      type: object
    SubmissionVariantSet-Input:
      properties:
        variant:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Input'
          title: Variant
          type: array
      required:
      - variant
      title: SubmissionVariantSet
      type: object
    SubmissionVariantSet-Output:
      properties:
        variant:
          items:
            $ref: '#/components/schemas/SubmissionVariant-Output'
          title: Variant
          type: array
      required:
      - variant
      title: SubmissionVariantSet
      type: object
    SubmittingOrgCreate:
      properties:
        clinvar_api_token:
          title: Clinvar Api Token
          type: string
        label:
          title: Label
          type: string
        owner:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: Owner
      required:
      - label
      - clinvar_api_token
      title: SubmittingOrgCreate
      type: object
    SubmittingOrgRead:
      properties:
        created:
          format: date-time
          title: Created
          type: string
        id:
          format: uuid
          title: Id
          type: string
        label:
          title: Label
          type: string
        owner:
          format: uuid
          title: Owner
          type: string
        updated:
          format: date-time
          title: Updated
          type: string
      required:
      - owner
      - label
      - id
      - created
      - updated
      title: SubmittingOrgRead
      type: object
    SubmittingOrgUpdate:
      properties:
        clinvar_api_token:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Api Token
        label:
          title: Label
          type: string
        owner:
          anyOf:
          - format: uuid
            type: string
          - type: 'null'
          title: Owner
      required:
      - label
      title: SubmittingOrgUpdate
      type: object
    SummaryResponse-Input:
      description: Represetation of server's response to a submission.
      properties:
        batch_processing_status:
          $ref: '#/components/schemas/BatchProcessingStatus'
        batch_release_status:
          $ref: '#/components/schemas/BatchReleaseStatus'
        deletions:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseDeletion-Input'
            type: array
          - type: 'null'
          title: Deletions
        submission_date:
          title: Submission Date
          type: string
        submission_name:
          title: Submission Name
          type: string
        submissions:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseSubmission-Input'
            type: array
          - type: 'null'
          title: Submissions
        total_count:
          title: Total Count
          type: integer
        total_delete_count:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Delete Count
        total_delete_errors:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Delete Errors
        total_delete_success:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Delete Success
        total_deleted:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Deleted
        total_errors:
          title: Total Errors
          type: integer
        total_public:
          title: Total Public
          type: integer
        total_success:
          title: Total Success
          type: integer
      required:
      - batch_processing_status
      - batch_release_status
      - submission_date
      - submission_name
      - total_count
      - total_errors
      - total_public
      - total_success
      title: SummaryResponse
      type: object
    SummaryResponse-Output:
      description: Represetation of server's response to a submission.
      properties:
        batch_processing_status:
          $ref: '#/components/schemas/BatchProcessingStatus'
        batch_release_status:
          $ref: '#/components/schemas/BatchReleaseStatus'
        deletions:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseDeletion-Output'
            type: array
          - type: 'null'
          title: Deletions
        submission_date:
          title: Submission Date
          type: string
        submission_name:
          title: Submission Name
          type: string
        submissions:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseSubmission-Output'
            type: array
          - type: 'null'
          title: Submissions
        total_count:
          title: Total Count
          type: integer
        total_delete_count:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Delete Count
        total_delete_errors:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Delete Errors
        total_delete_success:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Delete Success
        total_deleted:
          anyOf:
          - type: integer
          - type: 'null'
          title: Total Deleted
        total_errors:
          title: Total Errors
          type: integer
        total_public:
          title: Total Public
          type: integer
        total_success:
          title: Total Success
          type: integer
      required:
      - batch_processing_status
      - batch_release_status
      - submission_date
      - submission_name
      - total_count
      - total_errors
      - total_public
      - total_success
      title: SummaryResponse
      type: object
    SummaryResponseDeletion-Input:
      properties:
        delete_date:
          anyOf:
          - type: string
          - type: 'null'
          title: Delete Date
        delete_status:
          anyOf:
          - type: string
          - type: 'null'
          title: Delete Status
        errors:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseError-Input'
            type: array
          - type: 'null'
          title: Errors
        identifiers:
          $ref: '#/components/schemas/SummaryResponseDeletionIdentifier'
        processing_status:
          title: Processing Status
          type: string
      required:
      - identifiers
      - processing_status
      title: SummaryResponseDeletion
      type: object
    SummaryResponseDeletion-Output:
      properties:
        delete_date:
          anyOf:
          - type: string
          - type: 'null'
          title: Delete Date
        delete_status:
          anyOf:
          - type: string
          - type: 'null'
          title: Delete Status
        errors:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseError-Output'
            type: array
          - type: 'null'
          title: Errors
        identifiers:
          $ref: '#/components/schemas/SummaryResponseDeletionIdentifier'
        processing_status:
          title: Processing Status
          type: string
      required:
      - identifiers
      - processing_status
      title: SummaryResponseDeletion
      type: object
    SummaryResponseDeletionIdentifier:
      properties:
        clinvar_accession:
          title: Clinvar Accession
          type: string
        clinvar_local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Local Key
      required:
      - clinvar_accession
      title: SummaryResponseDeletionIdentifier
      type: object
    SummaryResponseError-Input:
      properties:
        input:
          items:
            $ref: '#/components/schemas/SummaryResponseErrorInput'
          title: Input
          type: array
        output:
          $ref: '#/components/schemas/SummaryResponseErrorOutput'
      required:
      - input
      - output
      title: SummaryResponseError
      type: object
    SummaryResponseError-Output:
      properties:
        input:
          items:
            $ref: '#/components/schemas/SummaryResponseErrorInput'
          title: Input
          type: array
        output:
          $ref: '#/components/schemas/SummaryResponseErrorOutput'
      required:
      - input
      - output
      title: SummaryResponseError
      type: object
    SummaryResponseErrorInput:
      properties:
        field:
          anyOf:
          - type: string
          - type: 'null'
          title: Field
        value:
          anyOf:
          - type: string
          - type: 'null'
          title: Value
      title: SummaryResponseErrorInput
      type: object
    SummaryResponseErrorOutput:
      properties:
        errors:
          items:
            $ref: '#/components/schemas/SummaryResponseErrorOutputError'
          title: Errors
          type: array
      required:
      - errors
      title: SummaryResponseErrorOutput
      type: object
    SummaryResponseErrorOutputError:
      properties:
        user_message:
          title: User Message
          type: string
      required:
      - user_message
      title: SummaryResponseErrorOutputError
      type: object
    SummaryResponseSubmission-Input:
      properties:
        clinvar_accession_version:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession Version
        errors:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseError-Input'
            type: array
          - type: 'null'
          title: Errors
        identifiers:
          $ref: '#/components/schemas/SummaryResponseSubmissionIdentifiers'
        processing_status:
          title: Processing Status
          type: string
        release_date:
          anyOf:
          - type: string
          - type: 'null'
          title: Release Date
        release_status:
          anyOf:
          - type: string
          - type: 'null'
          title: Release Status
      required:
      - identifiers
      - processing_status
      title: SummaryResponseSubmission
      type: object
    SummaryResponseSubmission-Output:
      properties:
        clinvar_accession_version:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession Version
        errors:
          anyOf:
          - items:
              $ref: '#/components/schemas/SummaryResponseError-Output'
            type: array
          - type: 'null'
          title: Errors
        identifiers:
          $ref: '#/components/schemas/SummaryResponseSubmissionIdentifiers'
        processing_status:
          title: Processing Status
          type: string
        release_date:
          anyOf:
          - type: string
          - type: 'null'
          title: Release Date
        release_status:
          anyOf:
          - type: string
          - type: 'null'
          title: Release Status
      required:
      - identifiers
      - processing_status
      title: SummaryResponseSubmission
      type: object
    SummaryResponseSubmissionIdentifiers:
      properties:
        clinvar_accession:
          anyOf:
          - type: string
          - type: 'null'
          title: Clinvar Accession
        clinvar_local_key:
          title: Clinvar Local Key
          type: string
        local_id:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Id
        local_key:
          anyOf:
          - type: string
          - type: 'null'
          title: Local Key
      required:
      - clinvar_local_key
      title: SummaryResponseSubmissionIdentifiers
      type: object
    TotalCursorPage_SubmissionActivityRead_:
      properties:
        current_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor to refetch the current page
          title: Current Page
        current_page_backwards:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor to refetch the current page starting from the last item
          title: Current Page Backwards
        items:
          items:
            $ref: '#/components/schemas/SubmissionActivityRead'
          title: Items
          type: array
        next_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the next page
          title: Next Page
        previous_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the previous page
          title: Previous Page
        total:
          anyOf:
          - type: integer
          - type: 'null'
          description: Total items
          title: Total
      required:
      - items
      title: TotalCursorPage[SubmissionActivityRead]
      type: object
    TotalCursorPage_SubmissionThreadRead_:
      properties:
        current_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor to refetch the current page
          title: Current Page
        current_page_backwards:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor to refetch the current page starting from the last item
          title: Current Page Backwards
        items:
          items:
            $ref: '#/components/schemas/SubmissionThreadRead'
          title: Items
          type: array
        next_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the next page
          title: Next Page
        previous_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the previous page
          title: Previous Page
        total:
          anyOf:
          - type: integer
          - type: 'null'
          description: Total items
          title: Total
      required:
      - items
      title: TotalCursorPage[SubmissionThreadRead]
      type: object
    TotalCursorPage_SubmittingOrgRead_:
      properties:
        current_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor to refetch the current page
          title: Current Page
        current_page_backwards:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor to refetch the current page starting from the last item
          title: Current Page Backwards
        items:
          items:
            $ref: '#/components/schemas/SubmittingOrgRead'
          title: Items
          type: array
        next_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the next page
          title: Next Page
        previous_page:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the previous page
          title: Previous Page
        total:
          anyOf:
          - type: integer
          - type: 'null'
          description: Total items
          title: Total
      required:
      - items
      title: TotalCursorPage[SubmittingOrgRead]
      type: object
    UserRead:
      description: 'Model to use for reading users.


        We expose the public OAuth account information.'
      properties:
        email:
          format: email
          title: Email
          type: string
        id:
          format: uuid
          title: Id
          type: string
        is_active:
          default: true
          title: Is Active
          type: boolean
        is_superuser:
          default: false
          title: Is Superuser
          type: boolean
        is_verified:
          default: false
          title: Is Verified
          type: boolean
        oauth_accounts:
          default: []
          items:
            $ref: '#/components/schemas/PublicOAuthAccount'
          title: Oauth Accounts
          type: array
      required:
      - id
      - email
      title: UserRead
      type: object
    UserUpdate:
      description: 'Model to use for updateing users.


        We expose the public OAuth account information.'
      properties:
        email:
          anyOf:
          - format: email
            type: string
          - type: 'null'
          title: Email
        is_active:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Is Active
        is_superuser:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Is Superuser
        is_verified:
          anyOf:
          - type: boolean
          - type: 'null'
          title: Is Verified
        oauth_accounts:
          default: []
          items:
            $ref: '#/components/schemas/PublicOAuthAccount'
          title: Oauth Accounts
          type: array
        password:
          anyOf:
          - type: string
          - type: 'null'
          title: Password
      title: UserUpdate
      type: object
    ValidationError:
      properties:
        loc:
          items:
            anyOf:
            - type: string
            - type: integer
          title: Location
          type: array
        msg:
          title: Message
          type: string
        type:
          title: Error Type
          type: string
      required:
      - loc
      - msg
      - type
      title: ValidationError
      type: object
    VariantPresence:
      description: Status of a variant in ClinVar.
      enum:
      - absent
      - present
      title: VariantPresence
      type: string
    VariantType:
      enum:
      - Insertion
      - Deletion
      - Duplication
      - Tandem duplication
      - copy number loss
      - copy number gain
      - Inversion
      - Translocation
      - Complex
      title: VariantType
      type: string
    Zygosity:
      enum:
      - GENO:0000135
      - NCIT:C45826
      - NCIT:C198518
      - reev:unknown_zygosity
      title: Zygosity
      type: string
  securitySchemes:
    APIKeyCookie:
      in: cookie
      name: fastapiusersauth
      type: apiKey
    OAuth2PasswordBearer:
      flows:
        password:
          scopes: {}
          tokenUrl: /api/v1/auth/login
      type: oauth2
info:
  title: REEV
  version: 0.1.0
openapi: 3.1.0
paths:
  /api/v1/acmgseqvar/create:
    post:
      description: 'Create a new ACMG Sequence Variant.


        :param acmgseqvar: ACMG Sequence Variant to create

        :type acmgseqvar: dict or :class:`.schemas.AcmgSeqVarCreate`

        :return: ACMG Sequence Variant

        :rtype: dict'
      operationId: create_acmgseqvar_api_v1_acmgseqvar_create_post
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/AcmgSeqVarCreate-Input'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/AcmgSeqVarCreate-Output'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Create Acmgseqvar
      tags:
      - acmgseqvar
  /api/v1/acmgseqvar/delete:
    delete:
      description: 'Delete a ACMG Sequence Variant by id.


        :param id: ACMG Sequence Variant id

        :type id: uuid

        :return: ACMG Sequence Variant

        :rtype: dict'
      operationId: delete_acmgseqvar_by_user_api_v1_acmgseqvar_delete_delete
      parameters:
      - in: query
        name: seqvar
        required: true
        schema:
          title: Seqvar
          type: string
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/AcmgSeqVarRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Acmgseqvar By User
      tags:
      - acmgseqvar
  /api/v1/acmgseqvar/delete-by-id:
    delete:
      description: 'Delete a ACMG Sequence Variant by id. Available only for superusers.


        :param id: ACMG Sequence Variant id

        :type id: uuid

        :return: ACMG Sequence Variant

        :rtype: dict'
      operationId: delete_acmgseqvar_api_v1_acmgseqvar_delete_by_id_delete
      parameters:
      - in: query
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/AcmgSeqVarRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Acmgseqvar
      tags:
      - acmgseqvar
  /api/v1/acmgseqvar/get:
    get:
      description: 'Get a ACMG Sequence Variant by id.


        :param id: ACMG Sequence Variant id

        :type id: uuid

        :return: ACMG Sequence Variant

        :rtype: dict

        :raises HTTPException 404: ACMG Sequence Variant not found

        :note: If user_agent is browser, return 204 Response'
      operationId: get_acmgseqvar_by_user_api_v1_acmgseqvar_get_get
      parameters:
      - in: query
        name: seqvar
        required: true
        schema:
          title: Seqvar
          type: string
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/AcmgSeqVarRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Acmgseqvar By User
      tags:
      - acmgseqvar
  /api/v1/acmgseqvar/get-by-id:
    get:
      description: 'Get a ACMG Sequence Variant by id. Available only for superusers.


        :param id: ACMG Sequence Variant id

        :type id: uuid

        :return: ACMG Sequence Variant

        :rtype: dict'
      operationId: get_acmgseqvar_api_v1_acmgseqvar_get_by_id_get
      parameters:
      - in: query
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/AcmgSeqVarRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Acmgseqvar
      tags:
      - acmgseqvar
  /api/v1/acmgseqvar/list:
    get:
      description: 'List ACMG Sequence Variants by user.


        :return: list of ACMG Sequence Variants

        :rtype: list'
      operationId: list_acmgseqvars_by_user_api_v1_acmgseqvar_list_get
      parameters:
      - in: query
        name: skip
        required: false
        schema:
          default: 0
          title: Skip
          type: integer
      - in: query
        name: limit
        required: false
        schema:
          default: 100
          title: Limit
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/AcmgSeqVarRead'
                title: Response List Acmgseqvars By User Api V1 Acmgseqvar List Get
                type: array
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Acmgseqvars By User
      tags:
      - acmgseqvar
  /api/v1/acmgseqvar/list-all:
    get:
      description: 'List all ACMG Sequence Variants. Available only for superusers.


        :param skip: number of ACMG Sequence Variants to skip

        :type skip: int

        :param limit: maximum number of ACMG Sequence Variants to return

        :type limit: int

        :return: list of ACMG Sequence Variants

        :rtype: list'
      operationId: list_acmgseqvars_api_v1_acmgseqvar_list_all_get
      parameters:
      - in: query
        name: skip
        required: false
        schema:
          default: 0
          title: Skip
          type: integer
      - in: query
        name: limit
        required: false
        schema:
          default: 100
          title: Limit
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/AcmgSeqVarRead'
                title: Response List Acmgseqvars Api V1 Acmgseqvar List All Get
                type: array
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Acmgseqvars
      tags:
      - acmgseqvar
  /api/v1/acmgseqvar/update:
    patch:
      description: 'Update a ACMG Sequence Variant.


        :param acmgseqvar: ACMG Sequence Variant to update

        :type acmgseqvar: dict or :class:`.schemas.AcmgSeqVarUpdate`

        :return: ACMG Sequence Variant

        :rtype: dict'
      operationId: update_acmgseqvar_api_v1_acmgseqvar_update_patch
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/AcmgSeqVarUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/AcmgSeqVarRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Update Acmgseqvar
      tags:
      - acmgseqvar
    put:
      description: 'Update a ACMG Sequence Variant.


        :param acmgseqvar: ACMG Sequence Variant to update

        :type acmgseqvar: dict or :class:`.schemas.AcmgSeqVarUpdate`

        :return: ACMG Sequence Variant

        :rtype: dict'
      operationId: update_acmgseqvar_api_v1_acmgseqvar_update_put
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/AcmgSeqVarUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/AcmgSeqVarRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Update Acmgseqvar
      tags:
      - acmgseqvar
  /api/v1/adminmsgs/:
    get:
      description: 'Retrieve all admin messages.


        :return: list of admin messages

        :rtype: list'
      operationId: read_adminmsgs_api_v1_adminmsgs__get
      parameters:
      - in: query
        name: skip
        required: false
        schema:
          default: 0
          title: Skip
          type: integer
      - in: query
        name: limit
        required: false
        schema:
          default: 100
          title: Limit
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/AdminMessageRead'
                title: Response Read Adminmsgs Api V1 Adminmsgs  Get
                type: array
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      summary: Read Adminmsgs
      tags:
      - adminmsgs
  /api/v1/auth/bearer/login:
    post:
      operationId: auth_bearer_login_api_v1_auth_bearer_login_post
      requestBody:
        content:
          application/x-www-form-urlencoded:
            schema:
              $ref: '#/components/schemas/Body_auth_bearer_login_api_v1_auth_bearer_login_post'
        required: true
      responses:
        '200':
          content:
            application/json:
              example:
                access_token: eyJ0eXAiOiJKV1QiLCJhbGciOiJIUzI1NiJ9.eyJ1c2VyX2lkIjoiOTIyMWZmYzktNjQwZi00MzcyLTg2ZDMtY2U2NDJjYmE1NjAzIiwiYXVkIjoiZmFzdGFwaS11c2VyczphdXRoIiwiZXhwIjoxNTcxNTA0MTkzfQ.M10bjOe45I5Ncu_uXvOmVV8QxnL-nZfcH96U90JaocI
                token_type: bearer
              schema:
                $ref: '#/components/schemas/BearerResponse'
          description: Successful Response
        '400':
          content:
            application/json:
              examples:
                LOGIN_BAD_CREDENTIALS:
                  summary: Bad credentials or the user is inactive.
                  value:
                    detail: LOGIN_BAD_CREDENTIALS
                LOGIN_USER_NOT_VERIFIED:
                  summary: The user is not verified.
                  value:
                    detail: LOGIN_USER_NOT_VERIFIED
              schema:
                $ref: '#/components/schemas/ErrorModel'
          description: Bad Request
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      summary: Auth:Bearer.Login
      tags:
      - auth
  /api/v1/auth/bearer/logout:
    post:
      operationId: auth_bearer_logout_api_v1_auth_bearer_logout_post
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
        '401':
          description: Missing token or inactive user.
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Auth:Bearer.Logout
      tags:
      - auth
  /api/v1/auth/cookie/login:
    post:
      operationId: auth_cookie_login_api_v1_auth_cookie_login_post
      requestBody:
        content:
          application/x-www-form-urlencoded:
            schema:
              $ref: '#/components/schemas/Body_auth_cookie_login_api_v1_auth_cookie_login_post'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
        '204':
          description: No Content
        '400':
          content:
            application/json:
              examples:
                LOGIN_BAD_CREDENTIALS:
                  summary: Bad credentials or the user is inactive.
                  value:
                    detail: LOGIN_BAD_CREDENTIALS
                LOGIN_USER_NOT_VERIFIED:
                  summary: The user is not verified.
                  value:
                    detail: LOGIN_USER_NOT_VERIFIED
              schema:
                $ref: '#/components/schemas/ErrorModel'
          description: Bad Request
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      summary: Auth:Cookie.Login
      tags:
      - auth
  /api/v1/auth/cookie/logout:
    post:
      operationId: auth_cookie_logout_api_v1_auth_cookie_logout_post
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
        '204':
          description: No Content
        '401':
          description: Missing token or inactive user.
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Auth:Cookie.Logout
      tags:
      - auth
  /api/v1/auth/oauth2-providers:
    get:
      description: 'Retrieve all admin messages.


        :return: list of admin messages

        :rtype: list'
      operationId: list_oauth2_providers_api_v1_auth_oauth2_providers_get
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/OAuth2ProviderPublic'
                title: Response List Oauth2 Providers Api V1 Auth Oauth2 Providers
                  Get
                type: array
          description: Successful Response
      summary: List Oauth2 Providers
      tags:
      - auth
  /api/v1/auth/request-verify-token:
    post:
      operationId: verify_request_token_api_v1_auth_request_verify_token_post
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/Body_verify_request_token_api_v1_auth_request_verify_token_post'
        required: true
      responses:
        '202':
          content:
            application/json:
              schema: {}
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      summary: Verify:Request-Token
      tags:
      - auth
  /api/v1/auth/verify:
    post:
      operationId: verify_verify_api_v1_auth_verify_post
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/Body_verify_verify_api_v1_auth_verify_post'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/UserRead'
          description: Successful Response
        '400':
          content:
            application/json:
              examples:
                VERIFY_USER_ALREADY_VERIFIED:
                  summary: The user is already verified.
                  value:
                    detail: VERIFY_USER_ALREADY_VERIFIED
                VERIFY_USER_BAD_TOKEN:
                  summary: Bad token, not existing user ornot the e-mail currently
                    set for the user.
                  value:
                    detail: VERIFY_USER_BAD_TOKEN
              schema:
                $ref: '#/components/schemas/ErrorModel'
          description: Bad Request
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      summary: Verify:Verify
      tags:
      - auth
  /api/v1/bookmarks/create:
    post:
      description: 'Create a new bookmark.


        :param bookmark: bookmark to create

        :type bookmark: dict or :class:`.schemas.BookmarkCreate`

        :return: bookmark

        :rtype: dict'
      operationId: create_bookmark_api_v1_bookmarks_create_post
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/BookmarkCreate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/BookmarkCreate'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Create Bookmark
      tags:
      - bookmarks
  /api/v1/bookmarks/delete:
    delete:
      description: 'Delete a bookmark for a current user by obj_type and obj_id.


        :param obj_type: type of object to bookmark

        :type obj_type: str (enum) - "gene", "seqvar", "strucvar"

        :param obj_id: id of object to bookmark

        :type obj_id: uuid

        :return: bookmark which was deleted

        :rtype: dict

        :raises HTTPException 404: if bookmark not found

        :note: if user_agent is browser, return 204 Response'
      operationId: delete_bookmark_for_user_api_v1_bookmarks_delete_delete
      parameters:
      - in: query
        name: obj_type
        required: true
        schema:
          title: Obj Type
          type: string
      - in: query
        name: obj_id
        required: true
        schema:
          title: Obj Id
          type: string
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/BookmarkRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Bookmark For User
      tags:
      - bookmarks
  /api/v1/bookmarks/delete-by-id:
    delete:
      description: 'Delete a bookmark. Available for superusers and bookmark owners.


        :param id: id of the bookmark

        :type id: uuid

        :return: bookmark which was deleted

        :rtype: dict'
      operationId: delete_bookmark_api_v1_bookmarks_delete_by_id_delete
      parameters:
      - in: query
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/BookmarkRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Bookmark
      tags:
      - bookmarks
  /api/v1/bookmarks/get:
    get:
      description: 'Get a bookmark for a current user by obj_type and obj_id.


        :param obj_type: type of object to bookmark

        :type obj_type: str (enum) - "gene", "seqvar", "strucvar"

        :param obj_id: id of object to bookmark

        :type obj_id: uuid

        :return: bookmark

        :rtype: dict

        :raises HTTPException 404: if bookmark not found

        :note: if user_agent is browser, return 204'
      operationId: get_bookmark_for_user_api_v1_bookmarks_get_get
      parameters:
      - in: query
        name: obj_type
        required: true
        schema:
          title: Obj Type
          type: string
      - in: query
        name: obj_id
        required: true
        schema:
          title: Obj Id
          type: string
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/BookmarkRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Bookmark For User
      tags:
      - bookmarks
  /api/v1/bookmarks/get-by-id:
    get:
      description: 'Get a bookmark by id. Available only for superusers.


        :param id: id of the bookmark

        :type id: uuid

        :return: bookmark

        :rtype: dict'
      operationId: get_bookmark_api_v1_bookmarks_get_by_id_get
      parameters:
      - in: query
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/BookmarkRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Bookmark
      tags:
      - bookmarks
  /api/v1/bookmarks/list:
    get:
      description: 'List bookmarks for a current user.


        :param skip: number of bookmarks to skip

        :type skip: int

        :param limit: maximum number of bookmarks to return

        :type limit: int

        :return: list of bookmarks

        :rtype: list'
      operationId: list_bookmarks_for_user_api_v1_bookmarks_list_get
      parameters:
      - in: query
        name: skip
        required: false
        schema:
          default: 0
          title: Skip
          type: integer
      - in: query
        name: limit
        required: false
        schema:
          default: 100
          title: Limit
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/BookmarkRead'
                title: Response List Bookmarks For User Api V1 Bookmarks List Get
                type: array
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Bookmarks For User
      tags:
      - bookmarks
  /api/v1/bookmarks/list-all:
    get:
      description: 'List all bookmarks. Available only for superusers.


        :param skip: number of bookmarks to skip

        :type skip: int

        :param limit: maximum number of bookmarks to return

        :type limit: int

        :return: list of bookmarks

        :rtype: list'
      operationId: list_bookmarks_api_v1_bookmarks_list_all_get
      parameters:
      - in: query
        name: skip
        required: false
        schema:
          default: 0
          title: Skip
          type: integer
      - in: query
        name: limit
        required: false
        schema:
          default: 100
          title: Limit
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/BookmarkRead'
                title: Response List Bookmarks Api V1 Bookmarks List All Get
                type: array
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Bookmarks
      tags:
      - bookmarks
  /api/v1/caseinfo/create:
    post:
      description: 'Create a new Case Information.


        :param caseinfo: Case Information to create

        :type caseinfo: dict or :class:`.schemas.CaseInfoCreate`

        :return: Case Information

        :rtype: dict'
      operationId: create_caseinfo_api_v1_caseinfo_create_post
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/CaseInfoCreate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/CaseInfoCreate'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Create Caseinfo
      tags:
      - caseinfo
  /api/v1/caseinfo/delete:
    delete:
      description: 'Delete a Case Information for a current user.


        :return: Case Information

        :rtype: dict'
      operationId: delete_caseinfo_for_user_api_v1_caseinfo_delete_delete
      parameters:
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/CaseInfoRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Caseinfo For User
      tags:
      - caseinfo
  /api/v1/caseinfo/delete-by-id:
    delete:
      description: 'Delete a Case Information by id. Available only for superusers.


        :param id: Case Information id

        :type id: uuid

        :return: Case Information

        :rtype: dict'
      operationId: delete_caseinfo_api_v1_caseinfo_delete_by_id_delete
      parameters:
      - in: query
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/CaseInfoRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Caseinfo
      tags:
      - caseinfo
  /api/v1/caseinfo/get:
    get:
      description: 'Get a Case Information for a current user.


        :return: Case Information

        :rtype: dict'
      operationId: get_caseinfo_for_user_api_v1_caseinfo_get_get
      parameters:
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/CaseInfoRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Caseinfo For User
      tags:
      - caseinfo
  /api/v1/caseinfo/get-by-id:
    get:
      description: 'Get a Case Information by id. Available only for superusers.


        :param id: Case Information id

        :type id: uuid

        :return: Case Information

        :rtype: dict'
      operationId: get_caseinfo_api_v1_caseinfo_get_by_id_get
      parameters:
      - in: query
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/CaseInfoRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Caseinfo
      tags:
      - caseinfo
  /api/v1/caseinfo/list:
    get:
      description: 'List all Case Information for a current user.


        :return: list of Case Information

        :rtype: list'
      operationId: list_caseinfos_for_user_api_v1_caseinfo_list_get
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/CaseInfoRead'
                title: Response List Caseinfos For User Api V1 Caseinfo List Get
                type: array
          description: Successful Response
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Caseinfos For User
      tags:
      - caseinfo
  /api/v1/caseinfo/list-all:
    get:
      description: 'List all Case Information. Available only for superusers.


        :param skip: number of Case Information to skip

        :type skip: int

        :param limit: maximum number of Case Information to return

        :type limit: int

        :return: list of Case Information

        :rtype: list'
      operationId: list_caseinfos_api_v1_caseinfo_list_all_get
      parameters:
      - in: query
        name: skip
        required: false
        schema:
          default: 0
          title: Skip
          type: integer
      - in: query
        name: limit
        required: false
        schema:
          default: 100
          title: Limit
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                items:
                  $ref: '#/components/schemas/CaseInfoRead'
                title: Response List Caseinfos Api V1 Caseinfo List All Get
                type: array
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Caseinfos
      tags:
      - caseinfo
  /api/v1/caseinfo/update:
    patch:
      description: 'Update a Case Information for a current user.


        :param caseinfo: Case Information to update

        :type caseinfo: dict or :class:`.schemas.CaseInfoUpdate`

        :return: Case Information

        :rtype: dict'
      operationId: update_caseinfo_for_user_api_v1_caseinfo_update_patch
      parameters:
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/CaseInfoUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/CaseInfoRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Update Caseinfo For User
      tags:
      - caseinfo
    put:
      description: 'Update a Case Information for a current user.


        :param caseinfo: Case Information to update

        :type caseinfo: dict or :class:`.schemas.CaseInfoUpdate`

        :return: Case Information

        :rtype: dict'
      operationId: update_caseinfo_for_user_api_v1_caseinfo_update_put
      parameters:
      - in: header
        name: user-agent
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: User-Agent
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/CaseInfoUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/CaseInfoRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Update Caseinfo For User
      tags:
      - caseinfo
  /api/v1/clinvarsub/submissionactivities/{submissionactivity_id}:
    put:
      description: 'Create a new submission activity in the given thread.


        :param submissionthread_id: Submission thread UUID.

        :return: Created submission activity.'
      operationId: update_submissionactivity_api_v1_clinvarsub_submissionactivities__submissionactivity_id__put
      parameters:
      - in: path
        name: submissionactivity_id
        required: true
        schema:
          title: Submissionactivity Id
          type: string
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/SubmissionActivityUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmissionActivityRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Update Submissionactivity
      tags:
      - clinvarsub
  /api/v1/clinvarsub/submissionthreads:
    get:
      description: 'List submission threads of current user in paginated fashion.


        :return: Paginated list of results.'
      operationId: list_submissionthreads_api_v1_clinvarsub_submissionthreads_get
      parameters:
      - in: query
        name: primary_variant_desc
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          title: Primary Variant Desc
      - description: Cursor for the next page
        in: query
        name: cursor
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the next page
          title: Cursor
      - description: Page size
        in: query
        name: size
        required: false
        schema:
          default: 50
          description: Page size
          maximum: 100
          minimum: 0
          title: Size
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/TotalCursorPage_SubmissionThreadRead_'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Submissionthreads
      tags:
      - clinvarsub
    post:
      description: 'Create a new submission thread.


        :param submissionthread: Data of submission thread to create.

        :return: Created submission thread.'
      operationId: create_submissionthread_api_v1_clinvarsub_submissionthreads_post
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/SubmissionThreadCreate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmissionThreadRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Create Submissionthread
      tags:
      - clinvarsub
  /api/v1/clinvarsub/submissionthreads/{submissionthread_id}:
    delete:
      description: 'Update submission thread (current user must be owner).


        :return: Paginated list of results.'
      operationId: delete_submissionthread_api_v1_clinvarsub_submissionthreads__submissionthread_id__delete
      parameters:
      - in: path
        name: submissionthread_id
        required: true
        schema:
          title: Submissionthread Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmissionThreadRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Submissionthread
      tags:
      - clinvarsub
    get:
      description: 'Retrieve submission thread (current user must be owner).


        :param id: Submission thread UUID.

        :return: Submission tread data.'
      operationId: get_submissionthread_by_id_api_v1_clinvarsub_submissionthreads__submissionthread_id__get
      parameters:
      - in: path
        name: submissionthread_id
        required: true
        schema:
          title: Submissionthread Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmissionThreadRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Submissionthread By Id
      tags:
      - clinvarsub
    put:
      description: 'Update submission thread (current user must be owner).


        :param id: Submission thread UUID.

        :return: Submission tread data.'
      operationId: update_submissionthread_api_v1_clinvarsub_submissionthreads__submissionthread_id__put
      parameters:
      - in: path
        name: submissionthread_id
        required: true
        schema:
          title: Submissionthread Id
          type: string
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/SubmissionThreadUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmissionThreadRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Update Submissionthread
      tags:
      - clinvarsub
  /api/v1/clinvarsub/submissionthreads/{submissionthread_id}/activities:
    get:
      description: 'List submission activities of given submission thread.


        Current user must be owner.


        :param submissionthread_id: Submission thread UUID.

        :return: Paginated list of results.'
      operationId: list_submissionactivities_api_v1_clinvarsub_submissionthreads__submissionthread_id__activities_get
      parameters:
      - in: path
        name: submissionthread_id
        required: true
        schema:
          title: Submissionthread Id
          type: string
      - description: Cursor for the next page
        in: query
        name: cursor
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the next page
          title: Cursor
      - description: Page size
        in: query
        name: size
        required: false
        schema:
          default: 50
          description: Page size
          maximum: 100
          minimum: 0
          title: Size
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/TotalCursorPage_SubmissionActivityRead_'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Submissionactivities
      tags:
      - clinvarsub
    post:
      description: 'Create a new submission activity in the given thread.


        :param submissionthread_id: Submission thread UUID.

        :return: Created submission activity.'
      operationId: create_submissionactivity_api_v1_clinvarsub_submissionthreads__submissionthread_id__activities_post
      parameters:
      - in: path
        name: submissionthread_id
        required: true
        schema:
          title: Submissionthread Id
          type: string
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/SubmissionActivityCreate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmissionActivityRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Create Submissionactivity
      tags:
      - clinvarsub
  /api/v1/clinvarsub/submittingorgs:
    get:
      description: 'List submitting orgs of current user in paginated fashion.


        :return: Paginated list of results.'
      operationId: list_submittingorgs_api_v1_clinvarsub_submittingorgs_get
      parameters:
      - description: Cursor for the next page
        in: query
        name: cursor
        required: false
        schema:
          anyOf:
          - type: string
          - type: 'null'
          description: Cursor for the next page
          title: Cursor
      - description: Page size
        in: query
        name: size
        required: false
        schema:
          default: 50
          description: Page size
          maximum: 100
          minimum: 0
          title: Size
          type: integer
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/TotalCursorPage_SubmittingOrgRead_'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: List Submittingorgs
      tags:
      - clinvarsub
    post:
      description: 'Create a new submitting org.


        :param submittingorg: Data of submitting org to create.

        :return: Created submitting org.'
      operationId: create_submittingorg_api_v1_clinvarsub_submittingorgs_post
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/SubmittingOrgCreate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmittingOrgRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Create Submittingorg
      tags:
      - clinvarsub
  /api/v1/clinvarsub/submittingorgs/{submittingorg_id}:
    delete:
      description: 'Update submitting org (current user must be owner).


        :return: Paginated list of results.'
      operationId: delete_submittingorg_api_v1_clinvarsub_submittingorgs__submittingorg_id__delete
      parameters:
      - in: path
        name: submittingorg_id
        required: true
        schema:
          title: Submittingorg Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmittingOrgRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Delete Submittingorg
      tags:
      - clinvarsub
    get:
      description: 'Retrieve submitting org (current user must be owner).


        :param id: Submitting org UUID.

        :return: Submitting org data.'
      operationId: get_submittingorg_by_id_api_v1_clinvarsub_submittingorgs__submittingorg_id__get
      parameters:
      - in: path
        name: submittingorg_id
        required: true
        schema:
          title: Submittingorg Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmittingOrgRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Get Submittingorg By Id
      tags:
      - clinvarsub
    put:
      description: 'Update submitting org (current user must be owner).


        :return: Paginated list of results.'
      operationId: update_submittingorg_api_v1_clinvarsub_submittingorgs__submittingorg_id__put
      parameters:
      - in: path
        name: submittingorg_id
        required: true
        schema:
          title: Submittingorg Id
          type: string
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/SubmittingOrgUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/SubmittingOrgRead'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Update Submittingorg
      tags:
      - clinvarsub
  /api/v1/users/me:
    get:
      operationId: users_current_user_api_v1_users_me_get
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/UserRead'
          description: Successful Response
        '401':
          description: Missing token or inactive user.
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Users:Current User
      tags:
      - users
    patch:
      operationId: users_patch_current_user_api_v1_users_me_patch
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/UserUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/UserRead'
          description: Successful Response
        '400':
          content:
            application/json:
              examples:
                UPDATE_USER_EMAIL_ALREADY_EXISTS:
                  summary: A user with this email already exists.
                  value:
                    detail: UPDATE_USER_EMAIL_ALREADY_EXISTS
                UPDATE_USER_INVALID_PASSWORD:
                  summary: Password validation failed.
                  value:
                    detail:
                      code: UPDATE_USER_INVALID_PASSWORD
                      reason: Password should beat least 3 characters
              schema:
                $ref: '#/components/schemas/ErrorModel'
          description: Bad Request
        '401':
          description: Missing token or inactive user.
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Users:Patch Current User
      tags:
      - users
  /api/v1/users/{id}:
    delete:
      operationId: users_delete_user_api_v1_users__id__delete
      parameters:
      - in: path
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '204':
          description: Successful Response
        '401':
          description: Missing token or inactive user.
        '403':
          description: Not a superuser.
        '404':
          description: The user does not exist.
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Users:Delete User
      tags:
      - users
    get:
      operationId: users_user_api_v1_users__id__get
      parameters:
      - in: path
        name: id
        required: true
        schema:
          title: Id
          type: string
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/UserRead'
          description: Successful Response
        '401':
          description: Missing token or inactive user.
        '403':
          description: Not a superuser.
        '404':
          description: The user does not exist.
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Users:User
      tags:
      - users
    patch:
      operationId: users_patch_user_api_v1_users__id__patch
      parameters:
      - in: path
        name: id
        required: true
        schema:
          title: Id
          type: string
      requestBody:
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/UserUpdate'
        required: true
      responses:
        '200':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/UserRead'
          description: Successful Response
        '400':
          content:
            application/json:
              examples:
                UPDATE_USER_EMAIL_ALREADY_EXISTS:
                  summary: A user with this email already exists.
                  value:
                    detail: UPDATE_USER_EMAIL_ALREADY_EXISTS
                UPDATE_USER_INVALID_PASSWORD:
                  summary: Password validation failed.
                  value:
                    detail:
                      code: UPDATE_USER_INVALID_PASSWORD
                      reason: Password should beat least 3 characters
              schema:
                $ref: '#/components/schemas/ErrorModel'
          description: Bad Request
        '401':
          description: Missing token or inactive user.
        '403':
          description: Not a superuser.
        '404':
          description: The user does not exist.
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Users:Patch User
      tags:
      - users
  /api/v1/utils/test-email/:
    post:
      description: 'Send out a test email.


        :param email_to: email address to send the test email to

        :type email_to: str

        :return: message

        :rtype: dict'
      operationId: test_email_api_v1_utils_test_email__post
      parameters:
      - in: query
        name: email_to
        required: true
        schema:
          format: email
          title: Email To
          type: string
      responses:
        '201':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/Msg'
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      security:
      - OAuth2PasswordBearer: []
      - APIKeyCookie: []
      summary: Test Email
      tags:
      - utils
  /internal/data-versions:
    get:
      description: 'Return versions of data and services used in the application.


        :return: A JSON response containing the versions of various data and services.

        :rtype: dict'
      operationId: data_versions_internal_data_versions_get
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Data Versions
    post:
      description: 'Return versions of data and services used in the application.


        :return: A JSON response containing the versions of various data and services.

        :rtype: dict'
      operationId: data_versions_internal_data_versions_post
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Data Versions
  /internal/frontend-settings:
    get:
      description: 'Return frontend settings.


        :return: frontend settings

        :rtype: dict'
      operationId: frontend_settings_internal_frontend_settings_get
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Frontend Settings
    post:
      description: 'Return frontend settings.


        :return: frontend settings

        :rtype: dict'
      operationId: frontend_settings_internal_frontend_settings_post
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Frontend Settings
  /internal/proxy/{path}:
    get:
      description: 'Reverse proxy to internal services.

        Supported services:

        - AnnoNARS

        - MeHARI

        - Viguno

        - NGINX

        - Dotty

        - CADA-Prio

        - AutoACMG


        :param request: request

        :type request: :class:`fastapi.Request`

        :return: response

        :rtype: :class:`fastapi.Response`'
      operationId: reverse_proxy_internal_proxy__path__get
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Reverse Proxy
      tags:
      - proxy
    post:
      description: 'Reverse proxy to internal services.

        Supported services:

        - AnnoNARS

        - MeHARI

        - Viguno

        - NGINX

        - Dotty

        - CADA-Prio

        - AutoACMG


        :param request: request

        :type request: :class:`fastapi.Request`

        :return: response

        :rtype: :class:`fastapi.Response`'
      operationId: reverse_proxy_internal_proxy__path__post
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Reverse Proxy
      tags:
      - proxy
  /internal/remote/acmg/{path}:
    get:
      description: 'Implement searching for ACMG classification for SNVs and indels.

        Proxy requests to the `WinterVar <http://wintervar.wglab.org/>`_ backend.


        :param request: request

        :type request: :class:`fastapi.Request`

        :return: ACMG classification

        :rtype: dict'
      operationId: acmg_internal_remote_acmg__path__get
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Acmg
      tags:
      - remote
  /internal/remote/cnv/acmg/{path}:
    get:
      description: 'Implement searching for ACMG classification for CNVs.

        Proxy requests to the `wAutoCNV <https://phoenix.bgi.com/>`_ backend.


        :param request: request

        :type request: :class:`fastapi.Request`

        :return: ACMG classification

        :rtype: dict'
      operationId: cnv_acmg_internal_remote_cnv_acmg__path__get
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Cnv Acmg
      tags:
      - remote
  /internal/remote/pubtator3-api/{path}:
    get:
      description: 'Proxy requests to the `PubTator 3 <https://www.ncbi.nlm.nih.gov/research/pubtator3-api/>`_
        backend.


        :param request: request

        :type request: :class:`fastapi.Request`

        :param path: path to append to the backend URL

        :type path: str

        :return: response

        :rtype: :class:`fastapi.responses.StreamingResponse`'
      operationId: pubtator3_api_internal_remote_pubtator3_api__path__get
      parameters:
      - in: path
        name: path
        required: true
        schema:
          title: Path
          type: string
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      summary: Pubtator3 Api
      tags:
      - remote
  /internal/remote/variantvalidator/{path}:
    get:
      description: 'Implement VariantValidator API. Proxy requests to the

        `VariantValidator <https://rest.variantvalidator.org/>`_ backend.


        :param request: request

        :type request: :class:`fastapi.Request`

        :param path: path to append to the backend URL

        :type path: str

        :return: response

        :rtype: :class:`fastapi.responses.StreamingResponse`'
      operationId: variantvalidator_internal_remote_variantvalidator__path__get
      parameters:
      - in: path
        name: path
        required: true
        schema:
          title: Path
          type: string
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
        '422':
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
          description: Validation Error
      summary: Variantvalidator
      tags:
      - remote
  /internal/version:
    get:
      description: 'Return reev version.


        :return: reev version

        :rtype: str'
      operationId: version_internal_version_get
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Version
    post:
      description: 'Return reev version.


        :return: reev version

        :rtype: str'
      operationId: version_internal_version_post
      responses:
        '200':
          content:
            application/json:
              schema: {}
          description: Successful Response
      summary: Version