![](\"https://raw.githubusercontent.com/biosustain/cameo/gh-pages/cameo_logo.png\"){kind=logo}
\n",
"\n",
"\n",
"cameo - **c**omputer **a**ssistend **m**etabolic **e**ngineering and **o**ptimization\n",
"\n",
"\n",
"Step 1: Load a model\n",
"-------------------\n",
"\n",
"Loading a model is easy. From the cameo package you can import the *load_model* function."
]
},
{
"cell_type": "code",
"execution_count": 1,
"metadata": {
"collapsed": false
},
"outputs": [],
"source": [
"from cameo import load_model"
]
},
{
"cell_type": "code",
"execution_count": 2,
"metadata": {
"collapsed": false
},
"outputs": [
{
"name": "stdout",
"output_type": "stream",
"text": [
"Read a metabolic model .\n",
"\n",
" Parameters\n",
" ----------\n",
" path_or_handle : path, fhandle or name.\n",
" One of:\n",
" * file path of a model file;\n",
" * file handle to a SBML or pickled model; or\n",
" * the identifier of a model in a web database (optflux.org/models)\n",
" solver_interface : solver_interface, optional\n",
" E.g. optlang.glpk_interface or any other optlang interface.\n",
" sanitize : boolean, optional\n",
" If reaction and metabolite IDs should be sanitized (works only for SBML models).\n",
" \n"
]
}
],
"source": [
"print(load_model.__doc__)"
]
},
{
"cell_type": "code",
"execution_count": 3,
"metadata": {
"collapsed": false
},
"outputs": [],
"source": [
"model = load_model(\"iJO1366\")"
]
},
{
"cell_type": "code",
"execution_count": 4,
"metadata": {
"collapsed": false
},
"outputs": [
{
"data": {
"text/html": [
"| Name | \n", "iJO1366 | \n", "
| Number of metabolites | \n", "1805 | \n", "
| Number of reactions | \n", "2583 | \n", "
| Reactions | \n", "4crsol_c --> 5drib_c --> aacald_c --> amob_c --> mththf_c --> oxam_c --> 0.234232 asn_dsh_L_c + 3e-06 lipopb_c + 0.333448 lys_dsh_L_c + 0.140101 utp_c + 0.234232 asp_dsh_L_c + 0.002288 pg181_c + 0.282306 ile_dsh_L_c + 0.055234 trp_dsh_L_c + 0.000223 chor_c + 3.1e-05 malcoa_c + 54.119975 atp_c + 0.001345 murein3p3p_p + 0.209684 ser_dsh_L_c + 0.133993 tyr_dsh_L_c + 0.007428 fe3_c + 0.000116 bmocogdp_c + 0.000324 zn2_c + 0.024805 datp_c + 2e-06 btn_c + 0.000223 gthrd_c + 0.000279 accoa_c + 0.012366 pe160_c + 0.008253 mg2_c + 0.009618 pe161_c + 0.004957 pe181_c + 0.180021 phe_dsh_L_c + 0.149336 met_dsh_L_c + 0.002944 clpn160_p + 0.004952 ca2_c + 0.005707 pg160_c + 0.209121 gtp_c + 0.004439 pg161_c + 0.18569 k_c + 0.005381 murein4p4p_p + 0.255712 gln_dsh_L_c + 0.000307 ni2_c + 0.000605 murein3px4p_p + 0.000223 mql8_c + 0.255712 glu_dsh_L_c + 0.005448 murein4px4p_p + 0.000673 murein4px4px4p_p + 0.000223 pheme_c + 0.411184 val_dsh_L_c + 0.008151 colipa_e + 0.006744 spmd_c + 0.000223 adocbl_c + 0.088988 cys_dsh_L_c + 0.000223 10fthf_c + 0.000223 mlthf_c + 7e-06 mobd_c + 7e-06 mococdp_c + 7e-06 mocogdp_c + 0.000223 enter_c + 0.031798 pe160_p + 0.004952 cl_c + 0.000223 hemeO_c + 0.000223 ribflv_c + 0.000168 coa_c + 0.000223 q8h2_c + 2.4e-05 cobalt2_c + 0.025612 dgtp_c + 0.000223 fad_c + 0.214798 pro_dsh_L_c + 0.006388 fe2_c + 0.437778 leu_dsh_L_c + 4.5e-05 nadh_c + 0.000112 nadp_c + 0.000335 nadph_c + 0.012379 nh4_c + 0.000658 mn2_c + 0.000248 4fe4s_c + 0.129799 ctp_c + 0.000223 thf_c + 0.000223 2dmmql8_c + 0.000674 cu2_c + 0.499149 ala_dsh_L_c + 0.024732 pe161_p + 48.752916 h2o_c + 0.012747 pe181_p + 0.000223 sheme_c + 2.5e-05 2fe2s_c + 0.004892 pg160_p + 0.003805 pg161_p + 0.28742 arg_dsh_L_c + 0.000223 thmpp_c + 0.001961 pg181_p + 0.03327 ptrc_c + 0.000223 amet_c + 0.004126 so4_c + 0.246506 thr_dsh_L_c + 0.025612 dctp_c + 0.00229 clpn161_p + 0.000223 pydx5p_c + 0.595297 gly_c + 9.8e-05 succoa_c + 5.5e-05 udcpdp_c + 0.092056 his_dsh_L_c + 0.154187 glycogen_c + 0.024805 dttp_c + 0.000223 5mthf_c + 0.001787 nad_c + 0.00118 clpn181_p --> 53.95 adp_c + 53.95 h_c + 0.749831 ppi_c + 53.945874 pi_c 0.221055 pro_dsh_L_c + 0.000223 10fthf_c + 0.000709 cu2_c + 0.215096 gtp_c + 7e-06 mobd_c + 0.241055 asn_dsh_L_c + 0.133508 ctp_c + 0.000576 coa_c + 0.153686 met_dsh_L_c + 0.185265 phe_dsh_L_c + 0.027017 dctp_c + 0.09158 cys_dsh_L_c + 0.513689 ala_dsh_L_c + 2.6e-05 2fe2s_c + 0.26316 glu_dsh_L_c + 0.343161 lys_dsh_L_c + 0.017868 pe160_c + 0.005205 ca2_c + 0.241055 asp_dsh_L_c + 2e-06 btn_c + 0.001831 nad_c + 0.295792 arg_dsh_L_c + 0.000223 thmpp_c + 0.137896 tyr_dsh_L_c + 0.056843 trp_dsh_L_c + 0.027017 dgtp_c + 0.000223 ribflv_c + 0.054154 pe161_c + 0.000223 sheme_c + 0.26316 gln_dsh_L_c + 0.008675 mg2_c + 0.612638 gly_c + 2.5e-05 cobalt2_c + 0.000323 ni2_c + 0.02106 pe161_p + 54.124831 atp_c + 0.000691 mn2_c + 0.000341 zn2_c + 0.144104 utp_c + 0.045946 pe160_p + 0.000223 pydx5p_c + 48.601527 h2o_c + 0.005205 cl_c + 0.000223 mlthf_c + 0.004338 so4_c + 0.215792 ser_dsh_L_c + 0.000223 pheme_c + 0.000223 2ohph_c + 0.026166 dttp_c + 0.290529 ile_dsh_L_c + 5.5e-05 udcpdp_c + 0.094738 his_dsh_L_c + 0.423162 val_dsh_L_c + 0.007808 fe3_c + 0.000447 nadp_c + 0.253687 thr_dsh_L_c + 0.013894 murein5px4p_p + 0.195193 k_c + 0.026166 datp_c + 0.450531 leu_dsh_L_c + 0.013013 nh4_c + 0.000122 bmocogdp_c + 0.019456 kdo2lipid4_e + 0.00026 4fe4s_c + 0.006715 fe2_c + 0.000223 amet_c + 0.000223 fad_c + 0.000223 thf_c --> 53.95 h_c + 0.773903 ppi_c + 53.95 adp_c + 53.945662 pi_c 12ppd_dsh_R_e --> 12ppd_dsh_S_e --> 14glucan_e --> 15dap_e --> 23camp_e --> 23ccmp_e --> 23cgmp_e --> 23cump_e --> 23dappa_e --> 26dap_dsh_M_e --> 2ddglcn_e --> 34dhpac_e --> 3amp_e --> 3cmp_e --> 3gmp_e --> 3hcinnm_e --> 3hpp_e --> 3hpppn_e --> 3ump_e --> 4abut_e --> 4hoxpacd_e --> 5dglcn_e --> 5mtr_e --> LalaDglu_e --> LalaDgluMdap_e --> LalaDgluMdapDala_e --> LalaLglu_e --> ac_e --> acac_e --> acald_e --> acgal_e --> acgal1p_e --> acgam_e --> acgam1p_e --> acmana_e --> acmum_e --> acnam_e --> acolipa_e --> acser_e --> ade_e --> adn_e --> adocbl_e --> ag_e --> agm_e --> akg_e --> ala_dsh_B_e --> ala_dsh_D_e --> ala_dsh_L_e --> alaala_e --> all_dsh_D_e --> alltn_e --> amp_e --> anhgm_e --> arab_dsh_L_e --> arbt_e --> arbtn_e --> arbtn_dsh_fe3_e --> arg_dsh_L_e --> ascb_dsh_L_e --> asn_dsh_L_e --> aso3_e --> asp_dsh_L_e --> btn_e --> but_e --> butso3_e --> ca2_e <=> cbi_e --> cbl1_e <=> cd2_e --> cgly_e --> chol_e --> chtbs_e --> cit_e --> cl_e <=> cm_e --> cmp_e --> co2_e <=> cobalt2_e <=> colipa_e --> colipap_e --> cpgn_e --> cpgn_dsh_un_e --> crn_e --> crn_dsh_D_e --> csn_e --> cu_e --> cu2_e <=> cyan_e --> cynt_e --> cys_dsh_D_e --> cys_dsh_L_e --> cytd_e --> dad_dsh_2_e --> damp_e --> dca_e --> dcmp_e --> dcyt_e --> ddca_e --> dgmp_e --> dgsn_e --> dha_e --> dimp_e --> din_e --> dms_e --> dmso_e --> dopa_e --> doxrbcn_e --> dtmp_e --> dump_e --> duri_e --> eca4colipa_e --> enlipa_e --> enter_e --> etha_e --> ethso3_e --> etoh_e --> f6p_e --> fald_e --> fe2_e <=> fe3_e <=> fe3dcit_e --> fe3dhbzs_e --> fe3hox_e --> fe3hox_dsh_un_e --> fecrm_e --> fecrm_dsh_un_e --> feenter_e --> feoxam_e --> feoxam_dsh_un_e --> for_e --> fru_e --> frulys_e --> fruur_e --> fuc_dsh_L_e --> fum_e --> fusa_e --> g1p_e --> g3pc_e --> g3pe_e --> g3pg_e --> g3pi_e --> g3ps_e --> g6p_e --> gal_e --> gal_dsh_bD_e --> gal1p_e --> galct_dsh_D_e --> galctn_dsh_D_e --> galctn_dsh_L_e --> galt_e --> galur_e --> gam_e --> gam6p_e --> gbbtn_e --> gdp_e --> glc_dsh_D_e <=> glcn_e --> glcr_e --> glcur_e --> glcur1p_e --> gln_dsh_L_e --> glu_dsh_L_e --> gly_e --> glyald_e --> glyb_e --> glyc_e --> glyc_dsh_R_e --> glyc2p_e --> glyc3p_e --> glyclt_e --> gmp_e --> gsn_e --> gthox_e --> gthrd_e --> gtp_e --> gua_e --> h_e <=> h2_e --> h2o_e <=> h2o2_e --> h2s_e --> hacolipa_e --> halipa_e --> hdca_e --> hdcea_e --> hg2_e --> his_dsh_L_e --> hom_dsh_L_e --> hxa_e --> hxan_e --> idon_dsh_L_e --> ile_dsh_L_e --> imp_e --> indole_e --> inost_e --> ins_e --> isetac_e --> k_e <=> kdo2lipid4_e --> lac_dsh_D_e --> lac_dsh_L_e --> lcts_e --> leu_dsh_L_e --> lipa_e --> lipa_cold_e --> lipoate_e --> lys_dsh_L_e --> lyx_dsh_L_e --> mal_dsh_D_e --> mal_dsh_L_e --> malt_e --> malthx_e --> maltpt_e --> malttr_e --> maltttr_e --> man_e --> man6p_e --> manglyc_e --> melib_e --> meoh_e --> met_dsh_D_e --> met_dsh_L_e --> metsox_dsh_R_dsh_L_e --> metsox_dsh_S_dsh_L_e --> mg2_e <=> mincyc_e --> minohp_e --> mmet_e --> mn2_e <=> mnl_e --> mobd_e <=> mso3_e --> n2o_e --> na1_e <=> nac_e --> nh4_e <=> ni2_e <=> nmn_e --> no_e --> no2_e --> no3_e --> novbcn_e --> o16a4colipa_e --> o2_e <=> o2s_e --> ocdca_e --> ocdcea_e --> octa_e --> orn_e --> orot_e --> pacald_e --> peamn_e --> phe_dsh_L_e --> pheme_e --> pi_e <=> pnto_dsh_R_e --> ppa_e --> ppal_e --> pppn_e --> ppt_e --> pro_dsh_L_e --> progly_e --> psclys_e --> pser_dsh_L_e --> ptrc_e --> pydam_e --> pydx_e --> pydxn_e --> pyr_e --> quin_e --> r5p_e --> rfamp_e --> rib_dsh_D_e --> rmn_e --> sbt_dsh_D_e --> sel_e <=> ser_dsh_D_e --> ser_dsh_L_e --> skm_e --> slnt_e <=> so2_e --> so3_e --> so4_e <=> spmd_e --> succ_e --> sucr_e --> sulfac_e --> tartr_dsh_D_e --> tartr_dsh_L_e --> taur_e --> tcynt_e --> thm_e --> thr_dsh_L_e --> thrp_e --> thym_e --> thymd_e --> tma_e --> tmao_e --> tre_e --> trp_dsh_L_e --> tsul_e --> ttdca_e --> ttdcea_e --> ttrcyc_e --> tungs_e <=> tym_e --> tyr_dsh_L_e --> tyrp_e --> uacgam_e --> udpacgal_e --> udpg_e --> udpgal_e --> udpglcur_e --> ump_e --> ura_e --> urea_e --> uri_e --> val_dsh_L_e --> xan_e --> xmp_e --> xtsn_e --> xyl_dsh_D_e --> xylu_dsh_L_e --> zn2_e <=> 12dgr120_p --> 12dgr120_c 12dgr140_p --> 12dgr140_c 12dgr141_p --> 12dgr141_c 12dgr160_p --> 12dgr160_c 12dgr161_p --> 12dgr161_c 12dgr180_p --> 12dgr180_c 12dgr181_p --> 12dgr181_c 12ppd_dsh_R_e <=> 12ppd_dsh_R_p 12ppd_dsh_R_p <=> 12ppd_dsh_R_c 12ppd_dsh_S_e <=> 12ppd_dsh_S_p 12ppd_dsh_S_p <=> 12ppd_dsh_S_c 14glucan_p + h2o_c + atp_c --> h_c + 14glucan_c + adp_c + pi_c 14glucan_e --> 14glucan_p 23camp_e <=> 23camp_p 23ccmp_e <=> 23ccmp_p 23cgmp_e <=> 23cgmp_p 23cump_e <=> 23cump_p h_p + 23dappa_p --> h_c + 23dappa_c 23dappa_e <=> 23dappa_p h2o_p + 23cump_p --> 3ump_p + h_p h2o_p + 23ccmp_p --> 3cmp_p + h_p 23camp_p + h2o_p --> 3amp_p + h_p 23cgmp_p + h2o_p --> 3gmp_p + h_p 26dap_dsh_M_e <=> 26dap_dsh_M_p 2ddecg3p_p --> 2ddecg3p_c 2tdecg3p_p --> 2tdecg3p_c 2tdec7eg3p_p --> 2tdec7eg3p_c 2hdecg3p_p --> 2hdecg3p_c 2hdec9eg3p_p --> 2hdec9eg3p_c 2odecg3p_p --> 2odecg3p_c 2odec11eg3p_p --> 2odec11eg3p_c 2agpe120_p --> 2agpe120_c 2agpe140_p --> 2agpe140_c 2agpe141_p --> 2agpe141_c 2agpe160_p --> 2agpe160_c 2agpe161_p --> 2agpe161_c 2agpe180_p --> 2agpe180_c 2agpe181_p --> 2agpe181_c atp_c + ddca_c + 2agpe120_c --> pe120_c + ppi_c + amp_c ttdca_c + atp_c + 2agpe140_c --> amp_c + ppi_c + pe140_c atp_c + ttdcea_c + 2agpe141_c --> amp_c + pe141_c + ppi_c hdca_c + atp_c + 2agpe160_c --> amp_c + ppi_c + pe160_c atp_c + hdcea_c + 2agpe161_c --> amp_c + pe161_c + ppi_c 2agpe180_c + atp_c + ocdca_c --> amp_c + pe180_c + ppi_c atp_c + 2agpe181_c + ocdcea_c --> pe181_c + ppi_c + amp_c 2agpg120_p --> 2agpg120_c 2agpg140_p --> 2agpg140_c 2agpg141_p --> 2agpg141_c 2agpg160_p --> 2agpg160_c 2agpg161_p --> 2agpg161_c 2agpg180_p --> 2agpg180_c 2agpg181_p --> 2agpg181_c atp_c + ddca_c + 2agpg120_c --> ppi_c + pg120_c + amp_c atp_c + ttdca_c + 2agpg140_c --> amp_c + ppi_c + pg140_c atp_c + ttdcea_c + 2agpg141_c --> pg141_c + amp_c + ppi_c atp_c + hdca_c + 2agpg160_c --> pg160_c + ppi_c + amp_c atp_c + hdcea_c + 2agpg161_c --> amp_c + pg161_c + ppi_c atp_c + ocdca_c + 2agpg180_c --> amp_c + pg180_c + ppi_c 2agpg181_c + atp_c + ocdcea_c --> amp_c + pg181_c + ppi_c h_c + 2dhguln_c + nadh_c --> glcn_c + nad_c h_c + 2dhguln_c + nadph_c --> nadp_c + glcn_c h_c + 2dhguln_c + nadh_c --> idon_dsh_L_c + nad_c h_c + 2dhguln_c + nadph_c --> nadp_c + idon_dsh_L_c h2o_c + 2mahmp_c --> h_c + 4ampm_c + pi_c 34dhpac_e <=> 34dhpac_p 3amac_c + h_c + h2o_c --> msa_c + nh4_c 3amp_e <=> 3amp_p 3cmp_e <=> 3cmp_p 3gmp_e <=> 3gmp_p 3hdecACP_c --> h2o_c + tdec2eACP_c 3hddecACP_c --> h2o_c + tddec2eACP_c 3hcddec5eACP_c --> t3c5ddeceACP_c + h2o_c 3hmrsACP_c --> h2o_c + tmrs2eACP_c 3hcmrs7eACP_c --> h2o_c + t3c7mrseACP_c 3hpalmACP_c --> h2o_c + tpalm2eACP_c 3hcpalm9eACP_c --> h2o_c + t3c9palmeACP_c 3hoctaACP_c --> h2o_c + toctd2eACP_c 3hcvac11eACP_c --> h2o_c + t3c11vaceACP_c 3haACP_c --> but2eACP_c + h2o_c 3hhexACP_c --> thex2eACP_c + h2o_c 3hoctACP_c --> h2o_c + toct2eACP_c h_c + 3hcinnm_c + nadh_c + o2_c --> h2o_c + dhcinnm_c + nad_c h_c + 3hpppn_c + nadh_c + o2_c --> h2o_c + dhpppn_c + nad_c 3hpp_e <=> 3hpp_p h_c + 3hpp_c --> 3hpp_p + h_p 3dhguln_c + atp_c --> 3dhgulnp_c + h_c + adp_c 3ump_p + h2o_p --> uri_p + pi_p 3cmp_p + h2o_p --> cytd_p + pi_p h2o_p + 3amp_p --> adn_p + pi_p h2o_p + 3gmp_p --> gsn_p + pi_p h_c + 3odecACP_c + nadph_c <=> 3hdecACP_c + nadp_c 3oddecACP_c + h_c + nadph_c <=> 3hddecACP_c + nadp_c h_c + 3ocddec5eACP_c + nadph_c --> nadp_c + 3hcddec5eACP_c h_c + nadph_c + 3omrsACP_c <=> nadp_c + 3hmrsACP_c h_c + 3ocmrs7eACP_c + nadph_c --> nadp_c + 3hcmrs7eACP_c h_c + 3opalmACP_c + nadph_c <=> 3hpalmACP_c + nadp_c h_c + 3ocpalm9eACP_c + nadph_c --> nadp_c + 3hcpalm9eACP_c h_c + 3ooctdACP_c + nadph_c <=> 3hoctaACP_c + nadp_c h_c + 3ocvac11eACP_c + nadph_c --> 3hcvac11eACP_c + nadp_c h_c + nadph_c + actACP_c <=> nadp_c + 3haACP_c h_c + nadph_c + 3ohexACP_c <=> 3hhexACP_c + nadp_c h_c + nadph_c + 3ooctACP_c <=> nadp_c + 3hoctACP_c h_c + ocACP_c + malACP_c --> co2_c + 3odecACP_c + ACP_c h_c + malACP_c + dcaACP_c --> co2_c + 3oddecACP_c + ACP_c h_c + cdec3eACP_c + malACP_c --> ACP_c + co2_c + 3ocddec5eACP_c h_c + ddcaACP_c + malACP_c --> co2_c + 3omrsACP_c + ACP_c h_c + cddec5eACP_c + malACP_c --> co2_c + ACP_c + 3ocmrs7eACP_c h_c + myrsACP_c + malACP_c --> co2_c + 3opalmACP_c + ACP_c tdeACP_c + h_c + malACP_c --> 3ocpalm9eACP_c + co2_c + ACP_c h_c + palmACP_c + malACP_c --> co2_c + ACP_c + 3ooctdACP_c h_c + hdeACP_c + malACP_c --> 3ocvac11eACP_c + ACP_c + co2_c h_c + butACP_c + malACP_c --> co2_c + ACP_c + 3ohexACP_c h_c + hexACP_c + malACP_c --> co2_c + ACP_c + 3ooctACP_c coa_c + oxadpcoa_c --> succoa_c + accoa_c atp_c + h2o_c + LalaDgluMdap_p --> h_c + adp_c + LalaDgluMdap_c + pi_c LalaDgluMdap_e <=> LalaDgluMdap_p 3ump_e <=> 3ump_p o2_p + h2o_p + dopa_p --> nh4_p + 34dhpac_p + h2o2_p 4hoxpacd_e <=> 4hoxpacd_p phthr_c + h2o_c --> 4hthr_c + pi_c LalaDgluMdapDala_c + h2o_c --> LalaDgluMdap_c + ala_dsh_D_c h2o_p + LalaDgluMdapDala_p --> LalaDgluMdap_p + ala_dsh_D_p LalaDgluMdapDala_p + h2o_c + atp_c --> h_c + LalaDgluMdapDala_c + adp_c + pi_c LalaDgluMdapDala_e <=> LalaDgluMdapDala_p h_c + 5dglcn_c + nadph_c <=> nadp_c + glcn_c 5dglcn_p + h_p <=> h_c + 5dglcn_c 5dglcn_e <=> 5dglcn_p h2o_c + dad_dsh_5_c --> ade_c + 5drib_c 5mtr_e <=> 5mtr_p h_c + 5mtr_c --> 5mtr_p + h_p ru5p_dsh_D_c <=> ara5p_c atp_c + ACP_c + ttdca_c --> myrsACP_c + amp_c + ppi_c atp_c + ACP_c + ttdcea_c --> tdeACP_c + amp_c + ppi_c hdca_c + atp_c + ACP_c --> amp_c + palmACP_c + ppi_c atp_c + ACP_c + hdcea_c --> hdeACP_c + amp_c + ppi_c atp_c + ocdcea_c + ACP_c --> amp_c + ppi_c + octeACP_c atp_c + ACP_c + ocdca_c --> amp_c + ppi_c + ocdcaACP_c atp_c + ACP_c + ddca_c --> amp_c + ddcaACP_c + ppi_c atp_c + ACP_c + dca_c --> amp_c + dcaACP_c + ppi_c atp_c + ACP_c + octa_c --> amp_c + ppi_c + ocACP_c aact_c + h2o_c + o2_c --> nh4_c + h2o2_c + mthgxl_c unagamu_c + dtdp4aaddg_c --> h_c + dtdp_c + unagamuf_c 14glucan_c --> malthx_c 14glucan_p --> malthx_p arbt6p_c + h2o_c --> g6p_c + hqn_c 4abut_c + akg_c --> glu_dsh_L_c + sucsal_c h2o_c + 4abutn_c + nad_c --> 2.0 h_c + nadh_c + 4abut_c 4abut_p + h_p --> h_c + 4abut_c 4abut_e <=> 4abut_p acac_c + accoa_c --> aacoa_c + ac_c 2.0 accoa_c <=> aacoa_c + coa_c btcoa_c + accoa_c <=> 3ohcoa_c + coa_c hxcoa_c + accoa_c <=> 3oocoa_c + coa_c accoa_c + occoa_c <=> 3odcoa_c + coa_c dcacoa_c + accoa_c <=> 3oddcoa_c + coa_c ddcacoa_c + accoa_c <=> coa_c + 3otdcoa_c accoa_c + tdcoa_c <=> coa_c + 3ohdcoa_c coa_c + 3oodcoa_c <=> accoa_c + pmtcoa_c h_p + acac_p <=> h_c + acac_c acac_e <=> acac_p coa_c + nad_c + acald_c <=> h_c + nadh_c + accoa_c acald_e <=> acald_p acald_p <=> acald_c anth_c + accoa_c --> acanth_c + coa_c gtp_c + h_c + adocbip_c --> agdpcbi_c + ppi_c atp_c + accoa_c + hco3_c --> h_c + adp_c + malcoa_c + pi_c atp_c + coa_c + ppa_c --> ppcoa_c + adp_c + pi_c h2o_p + acgal1p_p --> acgal_p + pi_p acgal1p_e <=> acgal1p_p acgal_e <=> acgal_p acgam1p_p + h2o_p --> acgam_p + pi_p acgam1p_e <=> acgam1p_p atp_c + acgam_c --> h_c + adp_c + acgam6p_c uacgam_c + udcpp_c --> ump_c + unaga_c pep_c + acgam_p --> acgam6p_c + pyr_c acgam_e <=> acgam_p atp_c + acglu_c --> acg5p_c + adp_c accoa_c + glu_dsh_L_c --> h_c + acglu_c + coa_c h_c + 2obut_c + pyr_c --> 2ahbut_c + co2_c ac_c + atp_c <=> adp_c + actp_c h_c + 2.0 pyr_c --> alac_dsh_S_c + co2_c h2o_c + acmum6p_c --> lac_dsh_D_c + acgam6p_c unaga_c + uacmamu_c --> h_c + unagamu_c + udp_c acmana_p + pep_c --> acmanap_c + pyr_c acmana_e <=> acmana_p pep_c + acmum_p --> acmum6p_c + pyr_c acmum_e --> acmum_p acnam_p + h_p --> h_c + acnam_c acnam_e <=> acnam_p acnam_c --> pyr_c + acmana_c fad_c + btcoa_c <=> fadh2_c + b2coa_c hxcoa_c + fad_c <=> hx2coa_c + fadh2_c fad_c + occoa_c <=> oc2coa_c + fadh2_c dcacoa_c + fad_c <=> dc2coa_c + fadh2_c fad_c + ddcacoa_c <=> dd2coa_c + fadh2_c fad_c + tdcoa_c <=> td2coa_c + fadh2_c pmtcoa_c + fad_c <=> hdd2coa_c + fadh2_c stcoa_c + fad_c <=> fadh2_c + od2coa_c ACP_c + accoa_c <=> acACP_c + coa_c acorn_c + h2o_c --> ac_c + orn_c atp_c + acolipa_p + h2o_c --> h_c + adp_c + acolipa_e + pi_c acon_dsh_T_c <=> acon_dsh_C_c acon_dsh_T_c + amet_c --> aconm_c + ahcys_c cit_c <=> acon_dsh_C_c + h2o_c h2o_c + acon_dsh_C_c <=> icit_c acorn_c + akg_c <=> acg5sa_c + glu_dsh_L_c pi_c + ddcaACP_c + h_c --> ACP_c + ddcap_c myrsACP_c + pi_c + h_c --> ACP_c + ttdcap_c tdeACP_c + pi_c + h_c --> ACP_c + ttdceap_c pi_c + palmACP_c + h_c --> ACP_c + hdcap_c hdeACP_c + pi_c + h_c --> ACP_c + hdceap_c pi_c + ocdcaACP_c + h_c --> ACP_c + ocdcap_c octeACP_c + pi_c + h_c --> ACP_c + ocdceap_c coa_c + apoACP_c --> pap_c + h_c + ACP_c atp_c + ac_c + coa_c --> amp_c + ppi_c + accoa_c acser_e <=> acser_p acser_c --> acser_p h_p + ac_p <=> h_c + ac_c ac_p + na1_p --> na1_c + ac_c ac_e <=> ac_p h_c + adn_c + h2o_c --> ins_c + nh4_c 4adcho_c --> h_c + 4abz_c + pyr_c chor_c + gln_dsh_L_c --> 4adcho_c + glu_dsh_L_c h2o_c + h_c + ade_c --> nh4_c + hxan_c h_p + ade_p <=> h_c + ade_c ade_e <=> ade_p atp_c + amp_c <=> 2.0 adp_c gtp_c + amp_c <=> adp_c + gdp_c amp_c + itp_c <=> adp_c + idp_c h_c + amet_c --> ametam_c + co2_c atp_c --> camp_c + ppi_c atp_c + adn_c --> h_c + adp_c + amp_c adn_c + h2o_c --> ade_c + rib_dsh_D_c adn_p + h_p --> h_c + adn_c adn_p + h_p <=> h_c + adn_c adn_e <=> adn_p adocbi_c + atp_c --> h_c + adp_c + adocbip_c agdpcbi_c + rdmbzi_c --> h_c + adocbl_c + gmp_c atp_c + h2o_c + adocbl_p --> h_c + adocbl_c + adp_c + pi_c h_p + adocbl_e --> h_c + adocbl_p h2o_c + adprib_c --> 2.0 h_c + amp_c + r5p_c prpp_c + ade_c --> ppi_c + amp_c atp_c + aps_c --> paps_c + h_c + adp_c dcamp_c <=> amp_c + fum_c 25aics_c <=> aicar_c + fum_c asp_dsh_L_c + imp_c + gtp_c --> 2.0 h_c + dcamp_c + gdp_c + pi_c h2o_c + acgam6p_c --> ac_c + gam6p_c h2o_c + anhgm3p_c --> anhgm_c + LalaDgluMdap_c anhgm3p_p + h2o_p --> LalaDgluMdap_p + anhgm_p h2o_c + anhgm3p_c --> anhm3p_c + acgam_c anhgm3p_p + h_p --> anhgm3p_c + h_c h2o_c + anhgm4p_c --> anhgm_c + LalaDgluMdapDala_c h2o_p + anhgm4p_p --> anhgm_p + LalaDgluMdapDala_p anhgm4p_c + h2o_c --> anhgm3p_c + ala_dsh_D_c anhgm4p_p + h2o_p --> anhgm3p_p + ala_dsh_D_p anhgm4p_c + h2o_c --> acgam_c + anhm4p_c h_p + anhgm4p_p --> h_c + anhgm4p_c anhgm_c + h2o_c --> acgam_c + anhm_c adphep_dsh_DD_c --> adphep_dsh_LD_c agm_c + h2o_c --> ptrc_c + urea_c h_p + anhgm_p --> h_c + anhgm_c agm_e <=> agm_p ddcaACP_c + 1ddecg3p_c --> ACP_c + pa120_c 1tdecg3p_c + myrsACP_c --> pa140_c + ACP_c tdeACP_c + 1tdec7eg3p_c --> pa141_c + ACP_c 1hdecg3p_c + palmACP_c --> pa160_c + ACP_c hdeACP_c + 1hdec9eg3p_c --> ACP_c + pa161_c 1odecg3p_c + ocdcaACP_c --> ACP_c + pa180_c octeACP_c + 1odec11eg3p_c --> ACP_c + pa181_c nadp_c + acg5sa_c + pi_c <=> h_c + nadph_c + acg5p_c h_e + ag_c --> h_c + ag_e ahcys_c + h2o_c --> ade_c + rhcys_c aicar_c + 10fthf_c <=> fprica_c + thf_c atp_c + air_c + hco3_c --> h_c + 5caiz_c + adp_c + pi_c 5aizc_c <=> 5caiz_c coa_c + nad_c + akg_c --> nadh_c + co2_c + succoa_c akg_p + h_p <=> h_c + akg_c akg_e <=> akg_p h2o_c + alaala_c --> 2.0 ala_dsh_D_c atp_c + h2o_c + alaala_p --> h_c + alaala_c + adp_c + pi_c atp_c + 2.0 ala_dsh_D_c <=> h_c + alaala_c + adp_c + pi_c alaala_e <=> alaala_p LalaDglu_c <=> LalaLglu_c ala_dsh_L_c <=> ala_dsh_D_c pydx5p_c + ala_dsh_D_c --> pyam5p_c + pyr_c ala_dsh_L_c + akg_c <=> glu_dsh_L_c + pyr_c pydx5p_c + ala_dsh_L_c --> pyam5p_c + pyr_c ala_dsh_L_c + atp_c + trnaala_c --> amp_c + alatrna_c + ppi_c h2o_c + ala_dsh_L_p + atp_c --> h_c + ala_dsh_L_c + adp_c + pi_c h_p + ala_dsh_L_p --> h_c + ala_dsh_L_c h_p + ala_dsh_L_p <=> h_c + ala_dsh_L_c na1_p + ala_dsh_L_p --> na1_c + ala_dsh_L_c ala_dsh_L_e <=> ala_dsh_L_p h_c + nadh_c + glyald_c <=> nad_c + glyc_c nad_c + etoh_c <=> h_c + acald_c + nadh_c pacald_c + h2o_c + nad_c <=> 2.0 h_c + nadh_c + pac_c h2o_c + acald_c + nad_c --> 2.0 h_c + nadh_c + ac_c nadp_c + h2o_c + acald_c --> 2.0 h_c + nadph_c + ac_c nadp_c + ppal_c + h2o_c --> 2.0 h_c + nadph_c + ppa_c btal_c + h2o_c + nad_c --> 2.0 h_c + nadh_c + but_c atp_c + all_dsh_D_c --> h_c + adp_c + all6p_c all6p_c <=> allul6p_c alltt_c + 2.0 h_c + 2.0 h2o_c --> co2_c + 2.0 nh4_c + urdglyc_c h2o_c + alltn_c --> h_c + alltt_c alltn_p + h_p <=> h_c + alltn_c alltn_e <=> alltn_p allul6p_c <=> f6p_c atp_c + h2o_c + all_dsh_D_p --> h_c + all_dsh_D_c + adp_c + pi_c all_dsh_D_e <=> all_dsh_D_p alpp_p + pe160_p --> 2agpe160_p + lpp_p alpp_p + pg160_p --> 2agpg160_p + lpp_p h_c + mthgxl_c + nadph_c --> acetol_c + nadp_c h_c + nadh_c + acetol_c --> 12ppd_dsh_R_c + nad_c altrn_c --> 2ddglcn_c + h2o_c anhm3p_c + h2o_c --> LalaDgluMdap_c + anhm_c h2o_c + anhm4p_c --> LalaDgluMdapDala_c + anhm_c h2o_c + anhm4p_c --> anhm3p_c + ala_dsh_D_c malttr_c + malt_c --> maltttr_c + glc_dsh_D_c maltttr_c + malt_c --> glc_dsh_D_c + maltpt_c malt_c + maltpt_c --> malthx_c + glc_dsh_D_c malt_c + malthx_c --> glc_dsh_D_c + malthp_c acmanap_c <=> acgam6p_c atp_c + acmana_c --> h_c + adp_c + acmanap_c amet_c + 8aonn_c <=> amob_c + dann_c amet_c + 2dmmql8_c --> h_c + mql8_c + ahcys_c h2o_c + air_c + nad_c --> 3.0 h_c + nadh_c + 4ampm_c + 2.0 for_c amp_c + h2o_c --> r5p_c + ade_c h2o_c + cgly_c --> gly_c + cys_dsh_L_c progly_c + h2o_c --> pro_dsh_L_c + gly_c amp_e <=> amp_p anhgm_e <=> anhgm_p atp_c + h2o_c + anhm_c --> h_c + adp_c + acmum6p_c anth_c + prpp_c --> ppi_c + pran_c chor_c + gln_dsh_L_c --> h_c + anth_c + glu_dsh_L_c + pyr_c h_c + 2aobut_c --> aact_c + co2_c pimACP_c + ala_dsh_L_c --> 8aonn_c + ACP_c + co2_c h2o_c + ap4a_c --> 2.0 h_c + 2.0 adp_c h_c + 2.0 atp_c --> ap4a_c + ppi_c h2o_c + ap5a_c --> 2.0 h_c + adp_c + atp_c ametam_c + 15dap_c --> h_c + 5mta_c + na15dap_c glyc3p_c + ddcap_c --> h_c + 1ddecg3p_c + pi_c glyc3p_c + ttdcap_c --> h_c + pi_c + 1tdecg3p_c glyc3p_c + ttdceap_c --> 1tdec7eg3p_c + h_c + pi_c hdcap_c + glyc3p_c --> h_c + pi_c + 1hdecg3p_c glyc3p_c + hdceap_c --> h_c + pi_c + 1hdec9eg3p_c ocdcap_c + glyc3p_c --> h_c + pi_c + 1odecg3p_c ocdceap_c + glyc3p_c --> h_c + 1odec11eg3p_c + pi_c h2o_c + ddcap_c --> 2.0 h_c + pi_c + ddca_c ttdcap_c + h2o_c --> 2.0 h_c + pi_c + ttdca_c ttdceap_c + h2o_c --> 2.0 h_c + pi_c + ttdcea_c h2o_c + hdcap_c --> 2.0 h_c + pi_c + hdca_c h2o_c + hdceap_c --> hdcea_c + 2.0 h_c + pi_c ocdcap_c + h2o_c --> 2.0 h_c + pi_c + ocdca_c h2o_c + ocdceap_c --> 2.0 h_c + pi_c + ocdcea_c h_c + nadh_c + aact_c <=> appl_c + nad_c h_c + 5apru_c + nadph_c --> nadp_c + 5aprbu_c arab_dsh_L_c <=> rbl_dsh_L_c fadh2_c + 2.0 arbtn_dsh_fe3_c --> 2.0 h_c + 2.0 arbtn_c + fad_c + 2.0 fe2_c fmnh2_c + 2.0 arbtn_dsh_fe3_c --> 2.0 h_c + fmn_c + 2.0 arbtn_c + 2.0 fe2_c rbflvrd_c + 2.0 arbtn_dsh_fe3_c --> 2.0 h_c + ribflv_c + 2.0 arbtn_c + 2.0 fe2_c arbtn_dsh_fe3_p + atp_c + h2o_c --> h_c + arbtn_dsh_fe3_c + adp_c + pi_c arbtn_e + fe3_e --> arbtn_dsh_fe3_e arbtn_p + h_p --> h_c + arbtn_e h_p + arbtn_dsh_fe3_e --> h_c + arbtn_dsh_fe3_p h_p + arbtn_c --> h_c + arbtn_p arbt_p + pep_c --> arbt6p_c + pyr_c arbt_e --> arbt_p atp_c + h2o_c + arab_dsh_L_p --> h_c + arab_dsh_L_c + adp_c + pi_c arab_dsh_L_p + h_p <=> h_c + arab_dsh_L_c h_p + arab_dsh_L_c --> h_c + arab_dsh_L_p arab_dsh_L_e <=> arab_dsh_L_p agm_c + arg_dsh_L_p <=> agm_p + arg_dsh_L_c h_c + arg_dsh_L_c --> co2_c + agm_c arg_dsh_L_p + h_p --> co2_p + agm_p orn_c + arg_dsh_L_p <=> orn_p + arg_dsh_L_c argsuc_c <=> arg_dsh_L_c + fum_c atp_c + citr_dsh_L_c + asp_dsh_L_c --> amp_c + h_c + ppi_c + argsuc_c atp_c + arg_dsh_L_c + trnaarg_c --> argtrna_c + ppi_c + amp_c atp_c + arg_dsh_L_p + h2o_c --> h_c + adp_c + arg_dsh_L_c + pi_c h_p + arg_dsh_L_c --> h_c + arg_dsh_L_p arg_dsh_L_e <=> arg_dsh_L_p nadp_c + pi_c + aspsa_c <=> h_c + nadph_c + 4pasp_c h2o_c + ascb6p_c --> 3dhgulnp_c + h_c ascb_dsh_L_p + pep_c --> ascb6p_c + pyr_c ascb_dsh_L_e <=> ascb_dsh_L_p h2o_c + asn_dsh_L_c --> nh4_c + asp_dsh_L_c asn_dsh_L_p + h2o_p --> nh4_p + asp_dsh_L_p atp_c + h2o_c + gln_dsh_L_c + asp_dsh_L_c --> amp_c + h_c + glu_dsh_L_c + asn_dsh_L_c + ppi_c atp_c + nh4_c + asp_dsh_L_c --> amp_c + h_c + asn_dsh_L_c + ppi_c atp_c + trnaasn_c + asn_dsh_L_c --> asntrna_c + ppi_c + amp_c atp_c + h2o_c + asn_dsh_L_p --> h_c + asn_dsh_L_c + adp_c + pi_c h_p + asn_dsh_L_p <=> h_c + asn_dsh_L_c asn_dsh_L_e <=> asn_dsh_L_p atp_c + h2o_c + aso3_c --> h_c + aso3_p + adp_c + pi_c aso3_e <=> aso3_p h_c + asp_dsh_L_c --> ala_dsh_B_c + co2_c asp_dsh_L_c + cbp_c --> h_c + pi_c + cbasp_c atp_c + asp_dsh_L_c <=> 4pasp_c + adp_c q8_c + asp_dsh_L_c --> h_c + q8h2_c + iasp_c mqn8_c + asp_dsh_L_c --> h_c + iasp_c + mql8_c fum_c + asp_dsh_L_c --> h_c + iasp_c + succ_c o2_c + asp_dsh_L_c --> h2o2_c + iasp_c + h_c asp_dsh_L_c --> nh4_c + fum_c asp_dsh_L_c + akg_c <=> glu_dsh_L_c + oaa_c atp_c + asp_dsh_L_c + trnaasp_c --> asptrna_c + ppi_c + amp_c atp_c + h2o_c + asp_dsh_L_p --> h_c + asp_dsh_L_c + adp_c + pi_c 2.0 h_p + asp_dsh_L_p --> 2.0 h_c + asp_dsh_L_c 3.0 h_p + asp_dsh_L_p --> 3.0 h_c + asp_dsh_L_c h_p + asp_dsh_L_p --> h_c + asp_dsh_L_c h_p + asp_dsh_L_p <=> h_c + asp_dsh_L_c asp_dsh_L_e <=> asp_dsh_L_p aso4_c + 2.0 gthrd_c --> gthox_c + h2o_c + aso3_c succoa_c + arg_dsh_L_c --> h_c + sucarg_c + coa_c nadp_c + athr_dsh_L_c <=> h_c + 2aobut_c + nadph_c h_c + atp_c + h2o_c --> itp_c + nh4_c h2o_c + atp_c --> h_c + adp_c + pi_c atp_c + prpp_c --> ppi_c + prbatp_c 4.0 h_p + adp_c + pi_c <=> 3.0 h_c + atp_c + h2o_c h_p + ala_dsh_B_p --> h_c + ala_dsh_B_c ala_dsh_B_e <=> ala_dsh_B_p h2o_c + betald_c + nad_c --> 2.0 h_c + glyb_c + nadh_c nadp_c + h2o_c + betald_c --> 2.0 h_c + nadph_c + glyb_c moco_c + mptamp_c --> bmoco_c + amp_c + cu2_c gtp_c + h_c + bmoco_c --> ppi_c + bmoco1gdp_c h_c + gtp_c + bmoco1gdp_c --> bmocogdp_c + ppi_c h2o_c + pap_c --> amp_c + pi_c h_c + nadh_c + btnso_c --> h2o_c + btn_c + nad_c h_c + nadph_c + btnso_c --> nadp_c + h2o_c + btn_c btn_p + h_p --> h_c + btn_c btn_e <=> btn_p dtbt_c + amet_c + 2fe2s_c --> h_c + dad_dsh_5_c + btn_c + 2fe1s_c + met_dsh_L_c but_c + accoa_c --> ac_c + btcoa_c atp_c + butso3_p + h2o_c --> h_c + butso3_c + adp_c + pi_c butso3_e <=> butso3_p h_p + but_p <=> h_c + but_c but_e <=> but_p h_c + gtp_c + bwco_c --> bwco1gdp_c + ppi_c bwco1gdp_c + gtp_c + h_c --> bwcogdp_c + ppi_c wco_c + mptamp_c --> bwco_c + amp_c + cu2_c h_p + ca2_c --> h_c + ca2_p ca2_e <=> ca2_p lys_dsh_L_p + h_p + 15dap_c --> h_c + 15dap_p + lys_dsh_L_c 2.0 h2o2_c --> 2.0 h2o_c + o2_c ca2_c + na1_p <=> na1_c + ca2_p h_c + atp_c + cbi_c <=> adocbi_c + pppi_c h_p + cbi_e --> h_c + cbi_p atp_c + cbi_p + h2o_c --> h_c + cbi_c + adp_c + pi_c atp_c + h2o_c + cbl1_p --> h_c + cbl1_c + adp_c + pi_c h_p + cbl1_e --> h_c + cbl1_p h_c + atp_c + cbl1_c <=> adocbl_c + pppi_c 2.0 h_c + cbm_c --> co2_c + nh4_c atp_c + co2_c + nh4_c <=> 2.0 h_c + adp_c + cbp_c hco3_c + 2.0 atp_c + h2o_c + gln_dsh_L_c --> 2.0 h_c + glu_dsh_L_c + cbp_c + 2.0 adp_c + pi_c atp_c + cdg_c + nh4_c --> h_c + preq0_c + h2o_c + adp_c + pi_c cd2_c + h2o_c + atp_c --> h_c + cd2_p + adp_c + pi_c h_p + cd2_c --> h_c + cd2_p cd2_e <=> cd2_p cd2_p --> cd2_c h2o_c + cdpdddecg_c --> 2.0 h_c + cmp_c + pa120_c h2o_c + cdpdtdecg_c --> 2.0 h_c + cmp_c + pa140_c h2o_c + cdpdtdec7eg_c --> 2.0 h_c + cmp_c + pa141_c h2o_c + cdpdhdecg_c --> 2.0 h_c + cmp_c + pa160_c h2o_c + cdpdhdec9eg_c --> 2.0 h_c + cmp_c + pa161_c h2o_c + cdpdodecg_c --> 2.0 h_c + cmp_c + pa180_c h2o_c + cdpdodec11eg_c --> 2.0 h_c + cmp_c + pa181_c 3.0 h_c + 2.0 nadph_c + preq0_c --> 2.0 nadp_c + preq1_c h_c + cph4_c --> cdg_c + nh4_c 4c2me_c + atp_c --> h_c + adp_c + 2p4c2me_c pe161_c + 2.0 amet_c --> 2.0 h_c + 2.0 ahcys_c + cpe160_c pg161_c + 2.0 amet_c --> 2.0 h_c + 2.0 ahcys_c + cpg160_c pe181_c + 2.0 amet_c --> 2.0 h_c + 2.0 ahcys_c + cpe180_c pg181_c + 2.0 amet_c --> 2.0 h_c + 2.0 ahcys_c + cpg180_c atp_c + h2o_c + cgly_p --> h_c + cgly_c + adp_c + pi_c cgly_e <=> cgly_p atp_c + h2o_c + chol_p --> h_c + chol_c + adp_c + pi_c chol_p + h_p --> h_c + chol_c chol_e <=> chol_p nad_c + chol_c --> h_c + betald_c + nadh_c chor_c --> pphn_c 3psme_c --> chor_c + pi_c chor_c --> 4hbz_c + pyr_c chtbs_p + pep_c --> chtbs6p_c + pyr_c chtbs_e <=> chtbs_p nadh_c + h_c + cinnm_c + o2_c --> cenchddd_c + nad_c cit_c --> ac_c + oaa_c h_p + cit_c --> h_c + cit_p succ_c + cit_p --> cit_c + succ_p cit_e <=> cit_p lipa_cold_p + atp_c + h2o_c --> h_c + lipa_cold_e + adp_c + pi_c h2o_p + clpn120_p --> pg120_p + pa120_p + h_p h2o_p + clpn140_p --> h_p + pg140_p + pa140_p h2o_p + clpn141_p --> pg141_p + pa141_p + h_p clpn160_p + h2o_p --> pg160_p + h_p + pa160_p h2o_p + clpn161_p --> pg161_p + pa161_p + h_p h2o_p + clpn180_p --> pg180_p + h_p + pa180_p h2o_p + clpn181_p --> pg181_p + pa181_p + h_p 2.0 pg120_p <=> clpn120_p + glyc_p 2.0 pg140_p <=> glyc_p + clpn140_p 2.0 pg141_p <=> clpn141_p + glyc_p 2.0 pg160_p <=> glyc_p + clpn160_p 2.0 pg161_p <=> clpn161_p + glyc_p 2.0 pg180_p <=> glyc_p + clpn180_p 2.0 pg181_p <=> clpn181_p + glyc_p h_c + 2.0 cl_p --> 2.0 cl_c + h_p cl_e <=> cl_p h2o_c + cmp_c --> csn_c + r5p_c cmp_e <=> cmp_p cm_e <=> cm_p h_p + cm_p --> h_c + cm_e co2_e <=> co2_p co2_p <=> co2_c atp_c + h2o_c + cobalt2_c --> h_c + cobalt2_p + adp_c + pi_c h_p + cobalt2_c --> h_c + cobalt2_p cobalt2_e <=> cobalt2_p cobalt2_p --> cobalt2_c udcpdp_p + colipa_p --> colipap_p + udcpp_p colipap_p + h2o_c + atp_c --> h_c + colipap_e + adp_c + pi_c atp_c + h2o_c + colipa_c --> h_c + pi_c + adp_c + colipa_p atp_c + h2o_c + colipa_p --> h_c + colipa_e + pi_c + adp_c fadh2_c + 2.0 cpgn_c --> 2.0 h_c + 2.0 cpgn_dsh_un_c + 2.0 fe2_c + fad_c fmnh2_c + 2.0 cpgn_c --> 2.0 h_c + fmn_c + 2.0 cpgn_dsh_un_c + 2.0 fe2_c rbflvrd_c + 2.0 cpgn_c --> 2.0 h_c + ribflv_c + 2.0 cpgn_dsh_un_c + 2.0 fe2_c h_p + cpgn_dsh_un_p --> h_c + cpgn_dsh_un_e h_p + cpgn_dsh_un_c --> h_c + cpgn_dsh_un_p cpgn_p + atp_c + h2o_c --> h_c + cpgn_c + adp_c + pi_c cpgn_dsh_un_e + fe3_e --> cpgn_e h_p + cpgn_e --> h_c + cpgn_p h2o_c + ahdt_c --> h_c + pppi_c + cph4_c + acald_c gtp_c + h2o_c --> cpmp_c + ppi_c 2.0 h_c + o2_c + cpppg3_c --> pppg9_c + 2.0 co2_c + 2.0 h2o_c 2.0 amet_c + cpppg3_c --> pppg9_c + 2.0 co2_c + 2.0 dad_dsh_5_c + 2.0 met_dsh_L_c bbtcoa_c + crn_c <=> crncoa_c + gbbtn_c atp_c + coa_c + crn_c --> crncoa_c + adp_c + pi_c crncoa_c <=> crnDcoa_c ctbtcoa_c + crn_c <=> crncoa_c + ctbt_c crncoa_c <=> ctbtcoa_c + h2o_c atp_c + crn_dsh_D_c + coa_c --> crnDcoa_c + adp_c + pi_c atp_c + h2o_c + crn_dsh_D_p --> crn_dsh_D_c + h_c + adp_c + pi_c h_p + crn_dsh_D_p <=> h_c + crn_dsh_D_c crn_dsh_D_e <=> crn_dsh_D_p atp_c + h2o_c + crn_p --> h_c + crn_c + adp_c + pi_c crn_p + h_p <=> h_c + crn_c gbbtn_c + crn_p --> crn_c + gbbtn_p crn_p + crn_dsh_D_c --> crn_dsh_D_p + crn_c crn_e <=> crn_p h2o_c + oaa_c + accoa_c --> h_c + coa_c + cit_c h2o_c + csn_c + h_c --> ura_c + nh4_c csn_p + h_p --> h_c + csn_c csn_e <=> csn_p atp_c + coa_c + ctbt_c --> adp_c + ctbtcoa_c + pi_c atp_c + h2o_c + ctbt_p --> h_c + ctbt_c + adp_c + pi_c h_p + ctbt_p <=> h_c + ctbt_c tdecoa_c <=> td2coa_c hdcoa_c <=> hdd2coa_c odecoa_c <=> od2coa_c atp_c + h2o_c + utp_c + gln_dsh_L_c --> 2.0 h_c + glu_dsh_L_c + ctp_c + adp_c + pi_c 4.0 h_p + o2_p + 4.0 cu_p --> 2.0 h2o_p + 4.0 cu2_p cu_c + atp_c + h2o_c --> pi_c + h_c + adp_c + cu_p cu2_c + h2o_c + atp_c --> h_c + cu2_p + adp_c + pi_c cu2_e <=> cu2_p cu2_p --> cu2_c h_e + cu_c --> h_c + cu_e cu_e <=> cu_p tsul_c + cyan_c --> h_c + so3_c + tcynt_c tsul_p + cyan_p --> h_p + so3_p + tcynt_p cyan_e <=> cyan_p hco3_c + 3.0 h_c + cynt_c --> 2.0 co2_c + nh4_c h_p + cynt_p --> h_c + cynt_c cynt_e <=> cynt_p h2o_c + cys_dsh_D_c --> pyr_c + h2s_c + nh4_c cys_dsh_L_c + h2o_c --> nh4_c + h2s_c + pyr_c atp_c + cys_dsh_D_p + h2o_c --> h_c + cys_dsh_D_c + adp_c + pi_c cys_dsh_D_e <=> cys_dsh_D_p h2s_c + acser_c --> h_c + ac_c + cys_dsh_L_c 2.0 h_c + 3sala_c --> ala_dsh_L_c + so2_c h2o_c + cyst_dsh_L_c --> pyr_c + hcys_dsh_L_c + nh4_c atp_c + trnacys_c + cys_dsh_L_c --> amp_c + ppi_c + cystrna_c atp_c + h2o_c + cys_dsh_L_c --> h_c + cys_dsh_L_p + adp_c + pi_c atp_c + h2o_c + cys_dsh_L_p --> h_c + cys_dsh_L_c + adp_c + pi_c cys_dsh_L_e <=> cys_dsh_L_p cys_dsh_L_c --> cys_dsh_L_p 2.0 h_c + mql8_c + 0.5 o2_c --> mqn8_c + h2o_c + 2.0 h_p 2.0 h_c + 0.5 o2_c + q8h2_c --> h2o_c + 2.0 h_p + q8_c 4.0 h_c + 0.5 o2_c + q8h2_c --> h2o_c + 4.0 h_p + q8_c h_c + cytd_c + h2o_c --> uri_c + nh4_c cytd_c + h2o_c --> csn_c + rib_dsh_D_c gtp_c + cytd_c --> h_c + gdp_c + cmp_c cytd_p + h_p --> h_c + cytd_c cytd_p + h_p <=> h_c + cytd_c cytd_e <=> cytd_p atp_c + cmp_c <=> adp_c + cdp_c atp_c + dcmp_c <=> dcdp_c + adp_c lac_dsh_D_p + h_p <=> h_c + lac_dsh_D_c lac_dsh_D_e <=> lac_dsh_D_p h2o_c + fad_c + ala_dsh_D_c --> fadh2_c + nh4_c + pyr_c h2o_c + dad_dsh_2_c + h_c --> din_c + nh4_c atp_c + damp_c <=> adp_c + dadp_c h_p + dad_dsh_2_p --> h_c + dad_dsh_2_c dad_dsh_2_e <=> dad_dsh_2_p 12dgr120_c + atp_c --> h_c + adp_c + pa120_c 12dgr140_c + atp_c --> h_c + adp_c + pa140_c atp_c + 12dgr141_c --> h_c + adp_c + pa141_c atp_c + 12dgr160_c --> h_c + adp_c + pa160_c atp_c + 12dgr161_c --> h_c + adp_c + pa161_c 12dgr180_c + atp_c --> h_c + adp_c + pa180_c 12dgr181_c + atp_c --> h_c + adp_c + pa181_c ala_dsh_D_p + h_p --> h_c + ala_dsh_D_c ala_dsh_D_e <=> ala_dsh_D_p damp_e <=> damp_p h2o_c + 23dappa_c --> 2.0 nh4_c + pyr_c h_c + 26dap_dsh_M_c --> lys_dsh_L_c + co2_c 26dap_dsh_LL_c <=> 26dap_dsh_M_c atp_c + h2o_c + 26dap_dsh_M_p --> h_c + 26dap_dsh_M_c + adp_c + pi_c 15dap_e <=> 15dap_p h_c + ctp_c + pa120_c --> ppi_c + cdpdddecg_c h_c + ctp_c + pa140_c --> ppi_c + cdpdtdecg_c h_c + ctp_c + pa141_c --> cdpdtdec7eg_c + ppi_c h_c + ctp_c + pa160_c --> ppi_c + cdpdhdecg_c h_c + ctp_c + pa161_c --> cdpdhdec9eg_c + ppi_c h_c + ctp_c + pa180_c --> ppi_c + cdpdodecg_c h_c + ctp_c + pa181_c --> cdpdodec11eg_c + ppi_c h2o_c + datp_c + h_c --> ditp_c + nh4_c ru5p_dsh_D_c --> h_c + for_c + db4p_c atp_c + co2_c + dann_c --> 3.0 h_c + dtbt_c + adp_c + pi_c h2o_c + chtbs6p_c --> acgam_c + acgam6p_c dca_e <=> dca_p dcmp_e <=> dcmp_p h2o_c + h_c + dctp_c --> dutp_c + nh4_c h_c + dcyt_c + h2o_c --> nh4_c + duri_c dcyt_p + h_p --> h_c + dcyt_c dcyt_e <=> dcyt_p ddca_e --> ddca_p atp_c + 2dh3dgal_c --> h_c + adp_c + 2dh3dgal6p_c 2ddglcn_p + h_p <=> h_c + 2ddglcn_c 2ddglcn_e <=> 2ddglcn_p 2ddglcn_c + atp_c --> h_c + 2ddg6p_c + adp_c h2o_c + e4p_c + pep_c --> 2dda7p_c + pi_c 2dh3dgal6p_c <=> g3p_c + pyr_c atp_c + dgmp_c <=> dgdp_c + adp_c dgmp_e <=> dgmp_p dgsn_p + h_p --> h_c + dgsn_c dgsn_e <=> dgsn_p 23dhacoa_c + h2o_c <=> 3hadpcoa_c 23dhmb_c --> 3mob_c + h2o_c 23dhmp_c --> h2o_c + 3mop_c dha_c + pep_c --> dhap_c + pyr_c dha_e <=> dha_p dha_p <=> dha_c nad_c + 23ddhb_c <=> 23dhb_c + h_c + nadh_c 23dhb_c + atp_c + h_c --> 23dhba_c + ppi_c h2o_c + 23dhbzs_c --> ser_dsh_L_c + 23dhb_c nad_c + cenchddd_c --> h_c + nadh_c + dhcinnm_c dhcinnm_c + o2_c --> h_c + hkntd_c h_c + 23dhdp_c + nadph_c --> nadp_c + thdp_c pyr_c + aspsa_c --> 2.0 h2o_c + h_c + 23dhdp_c h_c + dhf_c + nadph_c <=> nadp_c + thf_c atp_c + glu_dsh_L_c + dhpt_c --> h_c + dhf_c + adp_c + pi_c h_c + nadph_c + dhmpt_c --> thmnp_c + nadp_c h_c + dhna_c + octdp_c --> 2dmmql8_c + co2_c + ppi_c h_c + sbzcoa_c --> 14dhncoa_c + h2o_c h2o_c + 14dhncoa_c --> h_c + coa_c + dhna_c dhnpt_c <=> gcald_c + 6hmhpt_c dhnpt_c <=> dhmpt_c dhor_dsh_S_c + q8_c --> q8h2_c + orot_c dhor_dsh_S_c + mqn8_c --> orot_c + mql8_c dhor_dsh_S_c + fum_c --> orot_c + succ_c h2o_c + dhor_dsh_S_c <=> h_c + cbasp_c cechddd_c + nad_c --> h_c + nadh_c + dhpppn_c h2o_c + h_c + 25drapp_c --> nh4_c + 5apru_c 4abz_c + 6hmhptpp_c --> dhpt_c + ppi_c dhptd_c --> mdhdhf_c 3.0 h_c + nadph_c + dhptdn_c --> thptdn_c + nadp_c 3.0 h_c + nadh_c + dhptdn_c --> thptdn_c + nad_c ahdt_c <=> dhmptp_c 2dda7p_c --> pi_c + 3dhq_c 3dhq_c --> 3dhsk_c + h2o_c dimp_e <=> dimp_p h_p + din_p --> h_c + din_c din_e <=> din_p h_c + 25dkglcn_c + nadph_c --> nadp_c + 2dhguln_c h_c + 25dkglcn_c + nadh_c --> nad_c + 5dglcn_c h_c + 25dkglcn_c + nadph_c --> nadp_c + 5dglcn_c dmpp_c + ipdp_c --> grdp_c + ppi_c h_c + h2mb4p_c + nadh_c --> dmpp_c + h2o_c + nad_c 2omhmbl_c + amet_c --> h_c + q8h2_c + ahcys_c mql8_c + dmso_c --> dms_c + h2o_c + mqn8_c mql8_c + dmso_p --> dms_p + h2o_p + mqn8_c 2dmmql8_c + dmso_c --> 2dmmq8_c + h2o_c + dms_c 2dmmql8_c + dmso_p --> dms_p + h2o_p + 2dmmq8_c dmso_e <=> dmso_p dmso_p <=> dmso_c dms_e <=> dms_p h2o_c + dhpmp_c --> dhnpt_c + pi_c h2o_c + ahdt_c --> h_c + dhpmp_c + ppi_c h_c + nadh_c + 23doguln_c --> 3dhguln_c + nad_c dopa_e <=> dopa_p doxrbcn_e <=> doxrbcn_p h_p + doxrbcn_p --> h_c + doxrbcn_e dpcoa_c + atp_c --> h_c + adp_c + coa_c h_c + nadph_c + 2dhp_c --> nadp_c + pant_dsh_R_c 2dr5p_c --> acald_c + g3p_c q8_c + dsbard_p --> dsbaox_p + q8h2_c mqn8_c + dsbard_p --> dsbaox_p + mql8_c 2.0 gthrd_p + dsbcox_p --> gthox_p + dsbcrd_p trdrd_c + dsbdox_c --> trdox_c + dsbdrd_c 2.0 gthrd_p + dsbgox_p --> gthox_p + dsbgrd_p nadp_c + ser_dsh_D_c <=> h_c + nadph_c + 2amsa_c ser_dsh_D_p + h_p --> ser_dsh_D_c + h_c ser_dsh_D_e <=> ser_dsh_D_p tartr_dsh_D_c --> h2o_c + oaa_c atp_c + dtmp_c <=> dtdp_c + adp_c dtmp_e <=> dtmp_p dump_e <=> dump_p 56dura_c + nad_c <=> h_c + ura_c + nadh_c duri_c + atp_c --> h_c + adp_c + dump_c duri_c + pi_c <=> 2dr1p_c + ura_c duri_p + h_p --> h_c + duri_c duri_e <=> duri_p h2o_c + dutp_c --> h_c + dump_c + ppi_c h_c + dxyl5p_c + nadph_c --> nadp_c + 2me4p_c h_c + pyr_c + g3p_c --> co2_c + dxyl5p_c dxyl_c + atp_c --> h_c + adp_c + dxyl5p_c h2o_c + e4p_c + nad_c <=> 2.0 h_c + nadh_c + 4per_c h_c + nadh_c + tdec2eACP_c --> dcaACP_c + nad_c tdec2eACP_c + h_c + nadph_c --> dcaACP_c + nadp_c h_c + nadh_c + tddec2eACP_c --> ddcaACP_c + nad_c h_c + nadph_c + tddec2eACP_c --> nadp_c + ddcaACP_c h_c + nadh_c + t3c5ddeceACP_c --> nad_c + cddec5eACP_c h_c + nadph_c + t3c5ddeceACP_c --> nadp_c + cddec5eACP_c h_c + nadh_c + tmrs2eACP_c --> nad_c + myrsACP_c h_c + nadph_c + tmrs2eACP_c --> nadp_c + myrsACP_c nadh_c + t3c7mrseACP_c + h_c --> tdeACP_c + nad_c nadph_c + t3c7mrseACP_c + h_c --> tdeACP_c + nadp_c h_c + nadh_c + tpalm2eACP_c --> nad_c + palmACP_c h_c + nadph_c + tpalm2eACP_c --> nadp_c + palmACP_c h_c + nadh_c + t3c9palmeACP_c --> nad_c + hdeACP_c h_c + nadph_c + t3c9palmeACP_c --> nadp_c + hdeACP_c h_c + nadh_c + toctd2eACP_c --> nad_c + ocdcaACP_c h_c + nadph_c + toctd2eACP_c --> nadp_c + ocdcaACP_c h_c + nadh_c + t3c11vaceACP_c --> octeACP_c + nad_c h_c + t3c11vaceACP_c + nadph_c --> octeACP_c + nadp_c h_c + but2eACP_c + nadh_c --> butACP_c + nad_c but2eACP_c + h_c + nadph_c --> butACP_c + nadp_c thex2eACP_c + nadh_c + h_c --> hexACP_c + nad_c thex2eACP_c + nadph_c + h_c --> hexACP_c + nadp_c h_c + nadh_c + toct2eACP_c --> ocACP_c + nad_c h_c + nadph_c + toct2eACP_c --> nadp_c + ocACP_c atp_c + eca4colipa_p + h2o_c --> h_c + eca4colipa_e + adp_c + pi_c eca4und_p + colipa_p --> eca4colipa_p + h_p + udcpdp_p 2.0 unagamuf_p --> eca2und_p + h_p + udcpdp_p eca2und_p + unagamuf_p --> eca3und_p + h_p + udcpdp_p unagamuf_p + eca3und_p --> eca4und_p + h_p + udcpdp_p unagamuf_c --> unagamuf_p 3hbcoa_c <=> h2o_c + b2coa_c 3hhcoa_c <=> h2o_c + hx2coa_c 3hocoa_c <=> oc2coa_c + h2o_c 3hdcoa_c <=> h2o_c + dc2coa_c 3hddcoa_c <=> dd2coa_c + h2o_c 3htdcoa_c <=> td2coa_c + h2o_c 3hhdcoa_c <=> h2o_c + hdd2coa_c 3hodcoa_c <=> od2coa_c + h2o_c 2ddg6p_c --> g3p_c + pyr_c 6pgc_c --> h2o_c + 2ddg6p_c kdo2lipid4_c + ddcaACP_c --> ACP_c + kdo2lipid4L_c myrsACP_c + kdo2lipid4L_c --> ACP_c + lipa_c hdeACP_c + kdo2lipid4_c --> ACP_c + kdo2lipid4p_c kdo2lipid4p_c + myrsACP_c --> ACP_c + lipa_cold_c h_c + egmeACP_c + nadph_c --> nadp_c + gmeACP_c h2o_c + enlipa_p + atp_c --> h_c + enlipa_e + adp_c + pi_c 2pg_c <=> h2o_c + pep_c 3.0 23dhba_c + 3.0 seramp_c --> 6.0 amp_c + 9.0 h_c + enter_c 3.0 h2o_c + enter_c --> 3.0 h_c + 3.0 23dhbzs_c feenter_c + 3.0 h2o_c --> 3.0 h_c + 3.0 23dhbzs_c + fe3_c h_c + epmeACP_c + nadph_c --> pmeACP_c + nadp_c etha_c --> nh4_c + acald_c h_p + etha_p --> h_c + etha_c etha_e <=> etha_p atp_c + h2o_c + ethso3_p --> h_c + ethso3_c + adp_c + pi_c ethso3_e <=> ethso3_p etoh_e <=> etoh_p etoh_p <=> etoh_c f6p_c <=> dha_c + g3p_c h2o_c + f6p_c --> fru_c + pi_c f6p_p + 2.0 pi_c --> 2.0 pi_p + f6p_c f6p_e <=> f6p_p h2o_c + dcaACP_c --> h_c + dca_c + ACP_c h2o_c + ddcaACP_c --> h_c + ddca_c + ACP_c h2o_c + myrsACP_c --> ACP_c + h_c + ttdca_c h2o_c + tdeACP_c --> ACP_c + h_c + ttdcea_c h2o_c + palmACP_c --> ACP_c + h_c + hdca_c h2o_c + hdeACP_c --> h_c + hdcea_c + ACP_c h2o_c + ocACP_c --> h_c + octa_c + ACP_c h2o_c + dcacoa_c --> h_c + dca_c + coa_c h2o_c + ddcacoa_c --> h_c + coa_c + ddca_c tdcoa_c + h2o_c --> h_c + coa_c + ttdca_c h2o_c + tdecoa_c --> h_c + coa_c + ttdcea_c h2o_c + pmtcoa_c --> h_c + coa_c + hdca_c h2o_c + hdcoa_c --> h_c + hdcea_c + coa_c h2o_c + stcoa_c --> h_c + coa_c + ocdca_c h2o_c + odecoa_c --> h_c + coa_c + ocdcea_c h2o_c + hxcoa_c --> h_c + coa_c + hxa_c h2o_c + occoa_c --> h_c + coa_c + octa_c atp_c + coa_c + h_p + dca_p --> amp_c + h_c + dcacoa_c + ppi_c ddca_p + atp_c + coa_c + h_p --> h_c + amp_c + ddcacoa_c + ppi_c atp_c + coa_c + h_p + ttdca_p --> amp_c + h_c + tdcoa_c + ppi_c atp_c + ttdcea_p + coa_c + h_p --> amp_c + h_c + tdecoa_c + ppi_c atp_c + coa_c + h_p + hdca_p --> amp_c + h_c + pmtcoa_c + ppi_c atp_c + hdcea_p + coa_c + h_p --> amp_c + h_c + hdcoa_c + ppi_c atp_c + coa_c + h_p + ocdca_p --> h_c + stcoa_c + amp_c + ppi_c ocdcea_p + atp_c + coa_c + h_p --> amp_c + odecoa_c + h_c + ppi_c atp_c + hxa_p + coa_c + h_p --> h_c + amp_c + ppi_c + hxcoa_c atp_c + octa_p + coa_c + h_p --> amp_c + h_c + occoa_c + ppi_c h_c + nadh_c + fad_c --> nad_c + fadh2_c h_c + nadph_c + fad_c --> nadp_c + fadh2_c nad_c + hmgth_c <=> h_c + nadh_c + Sfglutth_c fald_e <=> fald_p fald_p <=> fald_c gthrd_c + fald_c <=> hmgth_c fdp_c <=> dhap_c + g3p_c s17bp_c <=> dhap_c + e4p_c fdp_c + h2o_c --> pi_c + f6p_c fuc_dsh_L_c <=> fcl_dsh_L_c fcl_dsh_L_c + atp_c --> h_c + adp_c + fc1p_c fc1p_c <=> dhap_c + lald_dsh_L_c ppp9_c + fe2_c --> 2.0 h_c + pheme_c 2.0 h_c + for_p + q8_c --> h_p + co2_p + q8h2_c 2.0 h_c + for_p + mqn8_c --> mql8_c + h_p + co2_p fmnh2_c + o2_c + isetac_c --> h_c + gcald_c + fmn_c + h2o_c + so3_c mso3_c + fmnh2_c + o2_c --> h_c + fmn_c + h2o_c + fald_c + so3_c o2_c + fmnh2_c + ethso3_c --> h_c + fmn_c + h2o_c + acald_c + so3_c butso3_c + fmnh2_c + o2_c --> h_c + h2o_c + btal_c + fmn_c + so3_c sulfac_c + fmnh2_c + o2_c --> h_c + glx_c + fmn_c + h2o_c + so3_c atp_c + h2o_c + fe2_p --> h_c + fe2_c + adp_c + pi_c h_p + fe2_p --> h_c + fe2_c fe2_c + h_p --> h_c + fe2_p fe2_e <=> fe2_p fe2_p --> fe2_c atp_c + h2o_c + fe3dcit_p --> fe3_c + h_c + 2.0 cit_c + adp_c + pi_c h_p + fe3dcit_e --> fe3dcit_p + h_c fe3dhbzs_c --> 23dhbzs_c + fe3_c atp_c + h2o_c + fe3dhbzs_p --> h_c + fe3dhbzs_c + adp_c + pi_c h_p + fe3dhbzs_e --> h_c + fe3dhbzs_p fadh2_c + 2.0 fe3hox_c --> 2.0 h_c + fad_c + 2.0 fe3hox_dsh_un_c + 2.0 fe2_c fmnh2_c + 2.0 fe3hox_c --> 2.0 h_c + fmn_c + 2.0 fe3hox_dsh_un_c + 2.0 fe2_c rbflvrd_c + 2.0 fe3hox_c --> 2.0 h_c + ribflv_c + 2.0 fe3hox_dsh_un_c + 2.0 fe2_c h_p + fe3hox_dsh_un_c --> h_c + fe3hox_dsh_un_p h_p + fe3hox_dsh_un_p --> h_c + fe3hox_dsh_un_e atp_c + fe3hox_p + h2o_c --> fe3hox_c + h_c + adp_c + pi_c fe3_e + fe3hox_dsh_un_e --> fe3hox_e h_p + fe3hox_e --> h_c + fe3hox_p 2.0 fe3_c + fadh2_c --> 2.0 h_c + 2.0 fe2_c + fad_c atp_c + h2o_c + fe3_p --> fe3_c + h_c + adp_c + pi_c fe3_e <=> fe3_p fadh2_c + 2.0 fecrm_c --> 2.0 h_c + fad_c + 2.0 fe2_c + 2.0 fecrm_dsh_un_c fmnh2_c + 2.0 fecrm_c --> 2.0 h_c + fmn_c + 2.0 fe2_c + 2.0 fecrm_dsh_un_c rbflvrd_c + 2.0 fecrm_c --> 2.0 h_c + ribflv_c + 2.0 fe2_c + 2.0 fecrm_dsh_un_c h_p + fecrm_dsh_un_p --> h_c + fecrm_dsh_un_e h_p + fecrm_dsh_un_c --> h_c + fecrm_dsh_un_p atp_c + fecrm_p + h2o_c --> h_c + fecrm_c + adp_c + pi_c fecrm_dsh_un_e + fe3_e --> fecrm_e h_p + fecrm_e --> h_c + fecrm_p fadh2_c + 2.0 feenter_c --> 2.0 h_c + 2.0 enter_c + fad_c + 2.0 fe2_c 2.0 feenter_c + fmnh2_c --> 2.0 h_c + fmn_c + 2.0 fe2_c + 2.0 enter_c 2.0 feenter_c + rbflvrd_c --> 2.0 h_c + ribflv_c + 2.0 fe2_c + 2.0 enter_c h2o_c + feenter_p + atp_c --> h_c + feenter_c + adp_c + pi_c fe3_e + enter_e --> feenter_e h_p + enter_p --> h_c + enter_e h_p + feenter_e --> h_c + feenter_p h_p + enter_c --> h_c + enter_p fadh2_c + 2.0 feoxam_c --> 2.0 h_c + 2.0 feoxam_dsh_un_c + fad_c + 2.0 fe2_c fmnh2_c + 2.0 feoxam_c --> 2.0 h_c + fmn_c + 2.0 feoxam_dsh_un_c + 2.0 fe2_c rbflvrd_c + 2.0 feoxam_c --> 2.0 h_c + ribflv_c + 2.0 feoxam_dsh_un_c + 2.0 fe2_c h_p + feoxam_dsh_un_p --> h_c + feoxam_dsh_un_e h_p + feoxam_dsh_un_c --> h_c + feoxam_dsh_un_p atp_c + h2o_c + feoxam_p --> h_c + feoxam_c + adp_c + pi_c feoxam_dsh_un_e + fe3_e --> feoxam_e h_p + feoxam_e --> h_c + feoxam_p 4.0 h_p + 4.0 fe2_p + o2_p --> 4.0 fe3_p + 2.0 h2o_p 2.0 h_c + h2o2_c + 2.0 4fe4s_c --> 2.0 fe3_c + 2.0 3fe4s_c + 2.0 h2o_c 2.0 h_c + 2.0 no_c + 2.0 4fe4s_c --> 2.0 fe3_c + 2.0 3fe4s_c + h2o_c + n2o_c 3fe4s_c + fe2_c --> 4fe4s_c suc6p_c + h2o_c --> fru_c + g6p_c h_c + for_c --> h2_c + co2_c 2.0 flxso_c + nadph_c --> h_c + nadp_c + 2.0 flxr_c ribflv_c + h_c + nadph_c --> nadp_c + rbflvrd_c h_c + nadh_c + ribflv_c --> nad_c + rbflvrd_c 10fthf_c + mettrna_c --> h_c + fmettrna_c + thf_c h_c + fmn_c + atp_c --> ppi_c + fad_c h_c + fmn_c + nadh_c --> nad_c + fmnh2_c h_c + fmn_c + nadph_c --> nadp_c + fmnh2_c h_c + 5fthf_c --> methf_c + h2o_c forcoa_c + oxa_c <=> for_c + oxalcoa_c for_p + h_p --> h_c + for_c for_e <=> for_p for_c --> for_p mql8_c + fum_c --> mqn8_c + succ_c 2dmmql8_c + fum_c --> 2dmmq8_c + succ_c f1p_c + atp_c --> h_c + adp_c + fdp_c h2o_c + frulysp_c <=> g6p_c + lys_dsh_L_c psclys_c <=> frulys_c frulys_c + atp_c --> h_c + adp_c + frulysp_c h_p + frulys_p --> h_c + frulys_c frulys_e <=> frulys_p fruur_p + h_p <=> h_c + fruur_c fruur_e <=> fruur_p fru_p + pep_c --> pyr_c + f6p_c fru_p + pep_c --> f1p_c + pyr_c fru_e <=> fru_p h2o_c + 10fthf_c --> h_c + for_c + thf_c atp_c + thf_c + for_c --> 10fthf_c + adp_c + pi_c fuc_dsh_L_e <=> fuc_dsh_L_p h_p + fuc_dsh_L_p <=> h_c + fuc_dsh_L_c fum_c + h2o_c <=> mal_dsh_L_c fum_p + 2.0 h_p --> 2.0 h_c + fum_c fum_p + 3.0 h_p --> 3.0 h_c + fum_c fum_e <=> fum_p fusa_e <=> fusa_p h_p + fusa_p --> h_c + fusa_e accoa_c + gam1p_c --> acgam1p_c + h_c + coa_c h2o_p + g1p_p --> glc_dsh_D_p + pi_p h_c + g1p_c + dttp_c --> ppi_c + dtdpglu_c g1p_e <=> g1p_p glu1sa_c <=> 5aop_c glyc2p_c + h2o_c --> glyc_c + pi_c glyc2p_p + h2o_p --> glyc_p + pi_p glyc3p_c + ddcaACP_c --> ACP_c + 1ddecg3p_c glyc3p_c + myrsACP_c --> 1tdecg3p_c + ACP_c glyc3p_c + tdeACP_c --> 1tdec7eg3p_c + ACP_c glyc3p_c + palmACP_c --> 1hdecg3p_c + ACP_c glyc3p_c + hdeACP_c --> ACP_c + 1hdec9eg3p_c glyc3p_c + ocdcaACP_c --> ACP_c + 1odecg3p_c octeACP_c + glyc3p_c --> ACP_c + 1odec11eg3p_c atp_c + g3pc_p + h2o_c --> h_c + g3pc_c + adp_c + pi_c g3pc_e <=> g3pc_p nadp_c + glyc3p_c <=> h_c + dhap_c + nadph_c q8_c + glyc3p_c --> dhap_c + q8h2_c mqn8_c + glyc3p_c --> dhap_c + mql8_c glyc3p_c + 2dmmq8_c --> 2dmmql8_c + dhap_c atp_c + h2o_c + g3pe_p --> h_c + g3pe_c + adp_c + pi_c g3pe_e <=> g3pe_p atp_c + h2o_c + g3pg_p --> h_c + g3pg_c + adp_c + pi_c g3pg_e <=> g3pg_p atp_c + h2o_c + g3pi_p --> h_c + g3pi_c + adp_c + pi_c g3pi_e <=> g3pi_p atp_c + g3ps_p + h2o_c --> h_c + g3ps_c + adp_c + pi_c g3ps_e <=> g3ps_p h2o_c + glyc3p_c --> glyc_c + pi_c glu5sa_c --> h_c + h2o_c + 1pyr5c_c h_c + nadph_c + glu5p_c --> nadp_c + glu5sa_c + pi_c h2o_c + gam6p_c --> nh4_c + f6p_c nadp_c + g6p_c <=> h_c + 6pgl_c + nadph_c g6p_c + h2o_c --> pi_c + glc_dsh_D_c g6p_p + 2.0 pi_c --> g6p_c + 2.0 pi_p g6p_e <=> g6p_p gal1p_p + h2o_p --> gal_p + pi_p gal1p_e <=> gal1p_p gal_dsh_bD_e <=> gal_dsh_bD_p galct_dsh_D_c --> 5dh4dglc_c + h2o_c galctn_dsh_L_c + nad_c --> h_c + tagur_c + nadh_c galctn_dsh_D_c --> 2dh3dgal_c + h2o_c galctn_dsh_L_p + h_p --> h_c + galctn_dsh_L_c galctn_dsh_L_e <=> galctn_dsh_L_p h_p + galctn_dsh_D_p --> h_c + galctn_dsh_D_c galctn_dsh_D_e <=> galctn_dsh_D_p galct_dsh_D_p + h_p <=> h_c + galct_dsh_D_c galct_dsh_D_e <=> galct_dsh_D_p gal_c + atp_c <=> h_c + adp_c + gal1p_c gal_dsh_bD_p --> gal_p melib_c + h2o_c --> gal_c + glc_dsh_D_c udpg_c + gicolipa_c --> h_c + gagicolipa_c + udp_c galt_p + pep_c --> galt1p_c + pyr_c galt_e <=> galt_p galur_p + h_p <=> h_c + galur_c galur_e <=> galur_p h_c + g1p_c + utp_c --> ppi_c + udpg_c atp_c + h2o_c + gal_p --> h_c + gal_c + adp_c + pi_c gal_p + h_p --> h_c + gal_c gal_e <=> gal_p gam6p_p + 2.0 pi_c --> 2.0 pi_p + gam6p_c gam6p_e <=> gam6p_p gam_p + pep_c --> pyr_c + gam6p_c gam_e <=> gam_p g3p_c + nad_c + pi_c <=> h_c + nadh_c + 13dpg_c 10fthf_c + gar_c <=> h_c + thf_c + fgam_c atp_c + for_c + gar_c --> h_c + fgam_c + adp_c + pi_c gbbtn_e <=> gbbtn_p gcald_c + h2o_c + nad_c --> 2.0 h_c + nadh_c + glyclt_c gdpddman_c --> gdpofuc_c gdp_c + atp_c --> amp_c + h_c + ppgpp_c gdpmann_c + h2o_c --> man_c + h_c + gdp_c h2o_c + gdpmann_c --> man1p_c + gmp_c + 2.0 h_c h2o_c + gdptp_c --> gtp_c + ppi_c gdp_e <=> gdp_p gln_dsh_L_c + f6p_c --> gam6p_c + glu_dsh_L_c nadp_c + ggbutal_c + h2o_c <=> 2.0 h_c + nadph_c + gg4abut_c h2o_c + gg4abut_c --> 4abut_c + glu_dsh_L_c h2o_c + o2_c + ggptrc_c --> nh4_c + ggbutal_c + h2o2_c atp_c + glu_dsh_L_c + ptrc_c --> h_c + ggptrc_c + adp_c + pi_c sucsal_c + nadh_c + h_c <=> ghb_c + nad_c ser_dsh_L_c + thf_c <=> gly_c + h2o_c + mlthf_c atp_c + gmp_c <=> adp_c + gdp_c glycogen_c --> bglycogen_c glc_dsh_D_c + accoa_c <=> acglc_dsh_D_c + coa_c glc_dsh_D_p + h2o_p + q8_c --> h_p + glcn_p + q8h2_c h_p + glcn_p <=> h_c + glcn_c glcn_e <=> glcn_p glycogen_c + pi_c --> g1p_c bglycogen_c + pi_c --> g1p_c 5dh4dglc_c --> 2h3oppan_c + pyr_c glcr_c --> 5dh4dglc_c + h2o_c glcr_p + h_p <=> h_c + glcr_c glcr_e <=> glcr_p adpglc_c --> h_c + glycogen_c + adp_c udpg_c + icolipa_c --> h_c + udp_c + gicolipa_c udpg_c + gagicolipa_c --> h_c + ggagicolipa_c + udp_c udpg_c + ggagicolipa_c --> h_c + gggagicolipa_c + udp_c glcur1p_e <=> glcur1p_p h_p + glcur_p <=> h_c + glcur_c glcur_e <=> glcur_p atp_c + glc_dsh_D_p + h2o_c --> h_c + glc_dsh_D_c + adp_c + pi_c glc_dsh_D_p + pep_c --> g6p_c + pyr_c glc_dsh_D_p + h_p --> h_c + glc_dsh_D_c glc_dsh_D_e <=> glc_dsh_D_p glc_dsh_D_e --> glc_dsh_D_p bglycogen_c --> glycogen_c h_c + g1p_c + atp_c --> adpglc_c + ppi_c atp_c + glu_dsh_L_c + nh4_c --> h_c + gln_dsh_L_c + adp_c + pi_c atp_c + trnagln_c + gln_dsh_L_c --> amp_c + ppi_c + glntrna_c gln_dsh_L_p + h2o_c + atp_c --> h_c + gln_dsh_L_c + adp_c + pi_c gln_dsh_L_e <=> gln_dsh_L_p nad_c + galt1p_c <=> h_c + tag6p_dsh_D_c + nadh_c atp_c + glu_dsh_L_c --> adp_c + glu5p_c 4abut_c + glu_dsh_L_p <=> 4abut_p + glu_dsh_L_c glu_dsh_L_c + cys_dsh_L_c + atp_c --> h_c + glucys_c + adp_c + pi_c h_c + glu_dsh_L_c --> 4abut_c + co2_c nadp_c + glu_dsh_L_c + h2o_c <=> h_c + nh4_c + akg_c + nadph_c gln_dsh_L_c + h2o_c --> glu_dsh_L_c + nh4_c gln_dsh_L_p + h2o_p --> nh4_p + glu_dsh_L_p h2o_c + prpp_c + gln_dsh_L_c --> glu_dsh_L_c + pram_c + ppi_c glu_dsh_D_c <=> glu_dsh_L_c h_c + nadph_c + akg_c + gln_dsh_L_c --> nadp_c + 2.0 glu_dsh_L_c h_c + nadph_c + glutrna_c --> nadp_c + glu1sa_c + trnaglu_c atp_c + glu_dsh_L_c + trnaglu_c --> amp_c + glutrna_c + ppi_c atp_c + h2o_c + glu_dsh_L_p --> h_c + glu_dsh_L_c + adp_c + pi_c h_p + glu_dsh_L_p <=> h_c + glu_dsh_L_c glu_dsh_L_p + na1_p --> na1_c + glu_dsh_L_c glu_dsh_L_e <=> glu_dsh_L_p h_c + 2.0 glx_c --> 2h3oppan_c + co2_c glyald_e <=> glyald_p glyald_p <=> glyald_c gly_c + accoa_c <=> 2aobut_c + coa_c atp_c + h2o_c + glyb_p --> h_c + glyb_c + adp_c + pi_c glyb_p + h_p --> h_c + glyb_c glyb_e <=> glyb_p glyc2p_p + h2o_c + atp_c --> h_c + glyc2p_c + adp_c + pi_c glyc2p_e <=> glyc2p_p glyc3p_p + atp_c + h2o_c --> h_c + glyc3p_c + adp_c + pi_c glyc3p_p + pi_c --> pi_p + glyc3p_c glyc3p_e <=> glyc3p_p glyc_dsh_R_p + h_p <=> h_c + glyc_dsh_R_c glyc_dsh_R_e <=> glyc_dsh_R_p nad_c + glyc_c --> h_c + dha_c + nadh_c glyc_dsh_R_c + atp_c --> h_c + adp_c + 3pg_c glyc_dsh_R_c + atp_c --> h_c + adp_c + 2pg_c gly_c + nad_c + thf_c --> nadh_c + co2_c + nh4_c + mlthf_c h_c + glx_c + nadh_c --> glyclt_c + nad_c h_c + glx_c + nadph_c --> glyclt_c + nadp_c glyclt_p + h_p <=> h_c + glyclt_c na1_p + glyclt_p --> glyclt_c + na1_c glyclt_e <=> glyclt_p q8_c + glyclt_c --> glx_c + q8h2_c mqn8_c + glyclt_c --> glx_c + mql8_c glyclt_c + 2dmmq8_c --> 2dmmql8_c + glx_c glyc_e <=> glyc_p glyc_c <=> glyc_p glyc_c + atp_c --> h_c + adp_c + glyc3p_c lgt_dsh_S_c + h2o_c --> h_c + lac_dsh_D_c + gthrd_c mthgxl_c + h2o_c --> h_c + lac_dsh_D_c atp_c + trnagly_c + gly_c --> amp_c + glytrna_c + ppi_c gly_p + h_p --> h_c + gly_c gly_p + h_p <=> h_c + gly_c na1_p + gly_p --> gly_c + na1_c gly_e <=> gly_p gdpmann_c --> gdpddman_c + h2o_c h_c + atp_c + gmhep1p_c --> adphep_dsh_DD_c + ppi_c gmhep7p_c + atp_c --> h_c + adp_c + gmhep17bp_c gmhep17bp_c + h2o_c --> pi_c + gmhep1p_c 2.0 h_c + nadph_c + gmp_c --> nadp_c + imp_c + nh4_c atp_c + h2o_c + xmp_c + gln_dsh_L_c --> amp_c + 2.0 h_c + glu_dsh_L_c + ppi_c + gmp_c gmp_e <=> gmp_p nadp_c + 6pgc_c --> ru5p_dsh_D_c + nadph_c + co2_c glcn_c + atp_c --> h_c + adp_c + 6pgc_c h_c + nadph_c + gdpofuc_c --> gdpfuc_c + nadp_c h2o_c + gp4g_c --> 2.0 h_c + 2.0 gdp_c h2o_c + g3pc_c --> h_c + glyc3p_c + chol_c h2o_p + g3pc_p --> glyc3p_p + h_p + chol_p h2o_c + g3pe_c --> h_c + glyc3p_c + etha_c h2o_p + g3pe_p --> glyc3p_p + h_p + etha_p h2o_c + g3ps_c --> h_c + ser_dsh_L_c + glyc3p_c h2o_p + g3ps_p --> ser_dsh_L_p + h_p + glyc3p_p h2o_c + g3pg_c --> h_c + glyc_c + glyc3p_c h2o_p + g3pg_p --> glyc3p_p + h_p + glyc_p h2o_c + g3pi_c --> h_c + inost_c + glyc3p_c h2o_p + g3pi_p --> glyc3p_p + h_p + inost_p ipdp_c + grdp_c --> ppi_c + frdp_c 2.0 gthrd_c + grxox_c --> gthox_c + grxrd_c gsn_c + atp_c --> h_c + adp_c + gmp_c h_p + gsn_p --> h_c + gsn_c gsn_e <=> gsn_p h2o_c + gtspmd_c --> gthrd_c + spmd_c atp_c + gthrd_c + spmd_c --> h_c + gtspmd_c + adp_c + pi_c gthox_e <=> gthox_p gthox_c + nadph_c + h_c <=> 2.0 gthrd_c + nadp_c h2o2_c + 2.0 gthrd_c --> 2.0 h2o_c + gthox_c gthrd_p + h2o_p --> glu_dsh_L_p + cgly_p atp_c + gthrd_c + h2o_c --> h_c + adp_c + pi_c + gthrd_p atp_c + h2o_c + gthrd_p --> h_c + gthrd_c + adp_c + pi_c gthrd_e <=> gthrd_p atp_c + glucys_c + gly_c --> gthrd_c + h_c + adp_c + pi_c h2o_c + gtp_c --> h_c + for_c + ahdt_c 3.0 h2o_c + gtp_c --> 2.0 h_c + for_c + ppi_c + 25drapp_c h2o_c + gdptp_c --> h_c + pi_c + ppgpp_c gtp_c + atp_c --> amp_c + h_c + gdptp_c h_c + gtp_c + h2o_c --> xtp_c + nh4_c gtp_e <=> gtp_p gtp_c --> 35cgmp_c + ppi_c h_c + gua_c + h2o_c --> nh4_c + xan_c gua_c + prpp_c --> gmp_c + ppi_c gua_p + h_p --> gua_c + h_c gua_e <=> gua_p gua_p <=> gua_c glcur_c <=> fruur_c galur_c <=> tagur_c h2o_p + glcur1p_p --> glcur_p + pi_p h2o2_e <=> h2o2_p h2o_e <=> h2o_p h2o_p <=> h2o_c 2.0 o2_c + h2s_c --> 2.0 h_c + so4_c h2s_c --> h2s_p h2s_e <=> h2s_p h2_e <=> h2_p h2_p <=> h2_c h_c + aacoa_c + nadh_c <=> 3hbcoa_c + nad_c h_c + nadh_c + 3ohcoa_c <=> 3hhcoa_c + nad_c h_c + 3oocoa_c + nadh_c <=> 3hocoa_c + nad_c h_c + 3odcoa_c + nadh_c <=> nad_c + 3hdcoa_c h_c + nadh_c + 3oddcoa_c <=> 3hddcoa_c + nad_c h_c + nadh_c + 3otdcoa_c <=> 3htdcoa_c + nad_c h_c + nadh_c + 3ohdcoa_c <=> 3hhdcoa_c + nad_c h_c + nadh_c + 3oodcoa_c <=> 3hodcoa_c + nad_c 3hadpcoa_c + nad_c <=> h_c + oxadpcoa_c + nadh_c octdp_c + 4hbz_c --> 3ophb_c + ppi_c h_p + 3hcinnm_p <=> h_c + 3hcinnm_c 3hcinnm_e <=> 3hcinnm_p h2o_c + co2_c <=> h_c + hco3_c hcys_dsh_L_c + amet_c --> met_dsh_L_c + h_c + ahcys_c mmet_c + hcys_dsh_L_c --> h_c + 2.0 met_dsh_L_c hdca_e --> hdca_p hdcea_e --> hdcea_p h2o_c + pheme_c + frdp_c --> ppi_c + hemeO_c hhlipa_c + atp_c --> h_c + phhlipa_c + adp_c hphhlipa_c + atp_c --> h_c + adp_c + phphhlipa_c lipa_c + adphep_dsh_LD_c --> h_c + adp_c + hlipa_c hlipa_c + adphep_dsh_LD_c --> h_c + adp_c + hhlipa_c phhlipa_c + adphep_dsh_LD_c --> h_c + adp_c + hphhlipa_c gggagicolipa_c + adphep_dsh_LD_c --> h_c + adp_c + colipa_c atp_c + 4mhetz_c --> h_c + adp_c + 4mpetz_c glc_dsh_D_c + atp_c --> h_c + adp_c + g6p_c man_c + atp_c --> man6p_c + h_c + adp_c fru_c + atp_c --> h_c + adp_c + f6p_c hxa_p + h_p <=> h_c + hxa_c hg2_c + h2o_c + atp_c --> h_c + hg2_p + adp_c + pi_c h_p + hg2_c --> h_c + hg2_p hg2_e <=> hg2_p histd_c + h2o_c + 2.0 nad_c --> 3.0 h_c + 2.0 nadh_c + his_dsh_L_c hisp_c + h2o_c --> histd_c + pi_c atp_c + his_dsh_L_c + trnahis_c --> amp_c + histrna_c + ppi_c h2o_c + atp_c + his_dsh_L_p --> h_c + his_dsh_L_c + adp_c + pi_c his_dsh_L_p + h_p <=> h_c + his_dsh_L_c his_dsh_L_e <=> his_dsh_L_p h2o_c + hkndd_c --> h_c + op4en_c + succ_c h2o_c + hkntd_c --> h_c + op4en_c + fum_c 4.0 ppbng_c + h2o_c --> hmbil_c + 4.0 nh4_c atp_c + 4ahmmp_c --> h_c + 4ampm_c + adp_c h_p + hom_dsh_L_c --> h_c + hom_dsh_L_p hom_dsh_L_e <=> hom_dsh_L_p 4h2opntn_c --> acald_c + pyr_c 6hmhpt_c + atp_c --> h_c + amp_c + 6hmhptpp_c dhpppn_c + o2_c --> h_c + hkndd_c 3hpppn_p + h_p <=> h_c + 3hpppn_c 3hpppn_e <=> 3hpppn_p hpyr_c <=> 2h3oppan_c h_c + nadh_c + hpyr_c --> glyc_dsh_R_c + nad_c h_c + hpyr_c + nadph_c --> nadp_c + glyc_dsh_R_c nadp_c + hom_dsh_L_c <=> h_c + nadph_c + aspsa_c hom_dsh_L_c + atp_c --> h_c + phom_c + adp_c succoa_c + hom_dsh_L_c --> coa_c + suchms_c glu_dsh_L_c + imacp_c --> hisp_c + akg_c h2o_c + hxan_c + nad_c --> h_c + nadh_c + xan_c hxa_e <=> hxa_p hxa_c + accoa_c --> ac_c + hxcoa_c hxan_c + prpp_c --> imp_c + ppi_c 2.0 h_c + q8_c + h2_c --> q8h2_c + 2.0 h_p 2.0 h_c + mqn8_c + h2_c --> 2.0 h_p + mql8_c h2_c + 2dmmq8_c + 2.0 h_c --> 2dmmql8_c + 2.0 h_p pyam5p_c + h2o_c --> pi_c + pydam_c hxan_e <=> hxan_p hxan_p <=> hxan_c h_e <=> h_p iscssh_c + iscu_c + 2fe1s_c --> 4.0 h_c + iscs_c + iscu_dsh_2fe2s_c fadh2_c + 2.0 iscssh_c + iscu_c + 2.0 fe2_c --> 6.0 h_c + 2.0 iscs_c + fad_c + iscu_dsh_2fe2s_c fadh2_c + 2.0 iscssh_c + 2.0 fe2_c + iscu_dsh_2fe2s_c --> 6.0 h_c + 2.0 iscs_c + iscu_dsh_2fe2s2_c + fad_c 4.0 h_c + iscu_dsh_2fe2s_c --> 2fe2s_c + iscu_c iscu_dsh_2fe2s2_c + 2.0 h_c + fadh2_c --> fad_c + iscu_dsh_4fe4s_c 4.0 h_c + iscu_dsh_4fe4s_c --> iscu_c + 4fe4s_c nadp_c + icit_c <=> nadph_c + akg_c + co2_c chor_c <=> ichor_c chor_c --> ichor_c ichor_c + h2o_c --> 23ddhb_c + pyr_c icit_c --> glx_c + succ_c cys_dsh_L_c + iscs_c --> iscssh_c + ala_dsh_L_c h_c + 5dglcn_c + nadh_c <=> idon_dsh_L_c + nad_c h_c + 5dglcn_c + nadph_c --> nadp_c + idon_dsh_L_c idon_dsh_L_p + h_p <=> h_c + idon_dsh_L_c idon_dsh_L_e <=> idon_dsh_L_p gln_dsh_L_c + prlp_c --> h_c + glu_dsh_L_c + aicar_c + eig3p_c eig3p_c --> h2o_c + imacp_c h_c + 2cpr5p_c --> h2o_c + co2_c + 3ig3p_c akg_c + ile_dsh_L_c <=> 3mop_c + glu_dsh_L_c atp_c + ile_dsh_L_c + trnaile_c --> amp_c + iletrna_c + ppi_c atp_c + h2o_c + ile_dsh_L_p --> h_c + ile_dsh_L_c + adp_c + pi_c h_p + ile_dsh_L_p <=> h_c + ile_dsh_L_c ile_dsh_L_e <=> ile_dsh_L_p h2o_c + imp_c <=> fprica_c h2o_c + imp_c + nad_c --> h_c + nadh_c + xmp_c imp_e <=> imp_p h_c + indole_c --> indole_p + h_p h_p + indole_p <=> h_c + indole_c indole_e <=> indole_p inost_p + na1_p --> inost_c + na1_c ins_c + h2o_c --> hxan_c + rib_dsh_D_c ins_c + atp_c --> h_c + adp_c + imp_c inost_e <=> inost_p h_p + ins_p --> h_c + ins_c h_p + ins_p <=> h_c + ins_c ins_e <=> ins_p ipdp_c <=> dmpp_c h_c + nadh_c + h2mb4p_c --> h2o_c + nad_c + ipdp_c nad_c + 3c2hmp_c --> 3c4mop_c + h_c + nadh_c 3c2hmp_c <=> 2ippm_c + h2o_c h2o_c + 2ippm_c <=> 3c3hmp_c 3mob_c + h2o_c + accoa_c --> h_c + 3c3hmp_c + coa_c isetac_p + atp_c + h2o_c --> h_c + isetac_c + adp_c + pi_c isetac_e <=> isetac_p atp_c + h2o_c + kdo2lipid4_c --> h_c + kdo2lipid4_p + adp_c + pi_c atp_c + kdo2lipid4_p + h2o_c --> h_c + kdo2lipid4_e + adp_c + pi_c nadp_c + 23dhmb_c <=> h_c + nadph_c + alac_dsh_S_c h_c + nadph_c + 2ahbut_c <=> nadp_c + 23dhmp_c h_c + acACP_c + malACP_c --> co2_c + ACP_c + actACP_c h_c + accoa_c + malACP_c --> co2_c + coa_c + actACP_c kdo_c + ctp_c --> ppi_c + ckdo_c h2o_c + kdo8p_c --> kdo_c + pi_c h2o_c + ara5p_c + pep_c --> pi_c + kdo8p_c h_c + 3dhgulnp_c --> xu5p_dsh_L_c + co2_c atp_c + k_p + h2o_c --> h_c + k_c + adp_c + pi_c k_p + h_p --> h_c + k_c h_p + k_c --> h_c + k_p k_e <=> k_p q8_c + lac_dsh_L_c --> pyr_c + q8h2_c mqn8_c + lac_dsh_L_c --> mql8_c + pyr_c h_p + lac_dsh_L_p <=> h_c + lac_dsh_L_c lac_dsh_L_e <=> lac_dsh_L_p uLa4n_p + colipa_p --> acolipa_p + udcpp_p lcts_c + h2o_c --> gal_c + glc_dsh_D_c h2o_p + lcts_p --> gal_p + glc_dsh_D_p h2o_c + LalaDgluMdap_c --> LalaDglu_c + 26dap_dsh_M_c LalaDglu_e <=> LalaDglu_p LalaDglu_p + h_p --> LalaDglu_c + h_c LalaLglu_e <=> LalaLglu_p h_p + LalaLglu_p --> h_c + LalaLglu_c h_c + mthgxl_c + nadh_c --> nad_c + lald_dsh_D_c h_c + mthgxl_c + nadph_c --> lald_dsh_L_c + nadp_c h2o_c + LalaLglu_c --> ala_dsh_L_c + glu_dsh_L_c h2o_c + nad_c + lald_dsh_L_c --> 2.0 h_c + nadh_c + lac_dsh_L_c h_c + lald_dsh_D_c + nadh_c <=> 12ppd_dsh_R_c + nad_c h_c + nadh_c + lald_dsh_L_c <=> 12ppd_dsh_S_c + nad_c h_p + lcts_c --> h_c + lcts_p lcts_e <=> lcts_p lcts_p + h_p <=> h_c + lcts_c lac_dsh_D_c + nad_c <=> h_c + pyr_c + nadh_c lac_dsh_D_c + q8_c --> q8h2_c + pyr_c 4mop_c + glu_dsh_L_c --> leu_dsh_L_c + akg_c atp_c + leu_dsh_L_c + trnaleu_c --> leutrna_c + amp_c + ppi_c atp_c + h2o_c + leu_dsh_L_p --> h_c + leu_dsh_L_c + adp_c + pi_c h_p + leu_dsh_L_p <=> h_c + leu_dsh_L_c leu_dsh_L_e <=> leu_dsh_L_p gthrd_c + mthgxl_c --> lgt_dsh_S_c atp_c + h2o_c + lipa_cold_c --> h_c + lipa_cold_p + adp_c + pi_c h_e + hdca_e + colipa_e --> hacolipa_e + h2o_e h_e + hdca_e + lipa_e --> halipa_e + h2o_e lipoamp_c --> amp_c + lipopb_c atp_c + lipoate_c --> lipoamp_c + ppi_c h2o_c + lipa_c + atp_c --> h_c + lipa_p + adp_c + pi_c lipa_p + h2o_c + atp_c --> h_c + lipa_e + adp_c + pi_c h_c + ocACP_c --> ACP_c + octapb_c h_c + nad_c + 2.0 amet_c + 4fe4s_c + octapb_c --> nadh_c + 2.0 dad_dsh_5_c + 2fe2s_c + lipopb_c + 2.0 fe2_c + 2.0 met_dsh_L_c lipoate_p + h_p --> h_c + lipoate_c lipoate_e <=> lipoate_p lipidX_c + u23ga_c --> h_c + udp_c + lipidAds_c h2o_p + 1ddecg3p_p --> ddca_p + glyc3p_p + h_p h2o_p + 1tdecg3p_p --> glyc3p_p + ttdca_p + h_p h2o_p + 1tdec7eg3p_p --> glyc3p_p + h_p + ttdcea_p h2o_p + 1hdecg3p_p --> glyc3p_p + hdca_p + h_p h2o_p + 1hdec9eg3p_p --> glyc3p_p + h_p + hdcea_p h2o_p + 1odecg3p_p --> glyc3p_p + ocdca_p + h_p h2o_p + 1odec11eg3p_p --> ocdcea_p + glyc3p_p + h_p h2o_p + 1agpe120_p --> ddca_p + h_p + g3pe_p h2o_p + 1agpe140_p --> ttdca_p + h_p + g3pe_p h2o_p + 1agpe141_p --> g3pe_p + h_p + ttdcea_p h2o_p + 1agpe160_p --> hdca_p + h_p + g3pe_p h2o_p + 1agpe161_p --> g3pe_p + h_p + hdcea_p h2o_p + 1agpe180_p --> ocdca_p + h_p + g3pe_p 1agpe181_p + h2o_p --> ocdcea_p + g3pe_p + h_p h2o_p + 1agpg120_p --> ddca_p + h_p + g3pg_p h2o_p + 1agpg140_p --> g3pg_p + ttdca_p + h_p h2o_p + 1agpg141_p --> ttdcea_p + h_p + g3pg_p h2o_p + 1agpg160_p --> g3pg_p + hdca_p + h_p h2o_p + 1agpg161_p --> g3pg_p + h_p + hdcea_p h2o_p + 1agpg180_p --> g3pg_p + ocdca_p + h_p h2o_p + 1agpg181_p --> ocdcea_p + g3pg_p + h_p h2o_c + 2ddecg3p_c --> 2.0 h_c + glyc3p_c + ddca_c h2o_c + 2tdecg3p_c --> 2.0 h_c + glyc3p_c + ttdca_c h2o_c + 2tdec7eg3p_c --> 2.0 h_c + glyc3p_c + ttdcea_c h2o_c + 2hdecg3p_c --> 2.0 h_c + hdca_c + glyc3p_c h2o_c + 2hdec9eg3p_c --> 2.0 h_c + glyc3p_c + hdcea_c h2o_c + 2odecg3p_c --> 2.0 h_c + glyc3p_c + ocdca_c h2o_c + 2odec11eg3p_c --> 2.0 h_c + glyc3p_c + ocdcea_c pg120_c + 2agpe120_c --> apg120_c + g3pe_c 2agpe140_c + pg140_c --> apg140_c + g3pe_c pg141_c + 2agpe141_c --> apg141_c + g3pe_c 2agpe160_c + pg160_c --> apg160_c + g3pe_c pg161_c + 2agpe161_c --> apg161_c + g3pe_c 2agpe180_c + pg180_c --> apg180_c + g3pe_c pg181_c + 2agpe181_c --> apg181_c + g3pe_c pg120_c + 2agpg120_c --> apg120_c + g3pg_c pg140_c + 2agpg140_c --> apg140_c + g3pg_c 2agpg141_c + pg141_c --> apg141_c + g3pg_c pg160_c + 2agpg160_c --> apg160_c + g3pg_c 2agpg161_c + pg161_c --> apg161_c + g3pg_c pg180_c + 2agpg180_c --> apg180_c + g3pg_c 2agpg181_c + pg181_c --> apg181_c + g3pg_c h2o_c + 2agpe120_c --> h_c + g3pe_c + ddca_c h2o_c + 2agpe140_c --> h_c + g3pe_c + ttdca_c h2o_c + 2agpe141_c --> h_c + g3pe_c + ttdcea_c h2o_c + 2agpe160_c --> h_c + hdca_c + g3pe_c h2o_c + 2agpe161_c --> h_c + hdcea_c + g3pe_c h2o_c + 2agpe180_c --> h_c + g3pe_c + ocdca_c 2agpe181_c + h2o_c --> h_c + g3pe_c + ocdcea_c h2o_c + 2agpg120_c --> h_c + g3pg_c + ddca_c h2o_c + 2agpg140_c --> h_c + ttdca_c + g3pg_c h2o_c + 2agpg141_c --> h_c + g3pg_c + ttdcea_c h2o_c + 2agpg160_c --> h_c + hdca_c + g3pg_c h2o_c + 2agpg161_c --> h_c + g3pg_c + hdcea_c h2o_c + 2agpg180_c --> h_c + ocdca_c + g3pg_c h2o_c + 2agpg181_c --> h_c + ocdcea_c + g3pg_c ser_dsh_L_c + nadp_c <=> h_c + nadph_c + 2amsa_c h_c + lys_dsh_L_c --> 15dap_c + co2_c atp_c + trnalys_c + lys_dsh_L_c --> amp_c + ppi_c + lystrna_c atp_c + h2o_c + lys_dsh_L_p --> h_c + lys_dsh_L_c + adp_c + pi_c lys_dsh_L_p + h_p --> h_c + lys_dsh_L_c h_p + lys_dsh_L_c --> h_c + lys_dsh_L_p lys_dsh_L_e <=> lys_dsh_L_p lyx_dsh_L_c --> xylu_dsh_L_c h_p + lyx_dsh_L_p --> h_c + lyx_dsh_L_c lyx_dsh_L_e <=> lyx_dsh_L_p nad_c + mnl1p_c <=> h_c + f6p_c + nadh_c h_c + malACP_c --> acACP_c + co2_c amet_c + malcoa_c --> malcoame_c + ahcys_c nad_c + mal_dsh_D_c --> co2_c + pyr_c + nadh_c mal_dsh_D_p + 2.0 h_p --> 2.0 h_c + mal_dsh_D_c mal_dsh_D_e <=> mal_dsh_D_p h2o_c + glx_c + accoa_c --> h_c + mal_dsh_L_c + coa_c malt_c + accoa_c <=> acmalt_c + coa_c malthx_p + atp_c + h2o_c --> h_c + malthx_c + adp_c + pi_c malthx_e --> malthx_p atp_c + maltpt_p + h2o_c --> h_c + adp_c + maltpt_c + pi_c maltpt_e --> maltpt_p atp_c + h2o_c + malttr_p --> h_c + adp_c + pi_c + malttr_c malttr_e --> malttr_p h2o_c + maltttr_p + atp_c --> maltttr_c + h_c + adp_c + pi_c maltttr_e --> maltttr_p malt_p + h2o_c + atp_c --> h_c + malt_c + adp_c + pi_c malt_p + pep_c --> pyr_c + malt6p_c malt_e --> malt_p 2.0 h_p + mal_dsh_L_p --> 2.0 h_c + mal_dsh_L_c 3.0 h_p + mal_dsh_L_p --> 3.0 h_c + mal_dsh_L_c h_p + mal_dsh_L_c --> h_c + mal_dsh_L_p mal_dsh_L_e <=> mal_dsh_L_p h_c + man1p_c + gdp_c --> gdpmann_c + pi_c man6p_c <=> f6p_c man6p_p + 2.0 pi_c --> man6p_c + 2.0 pi_p man6p_e <=> man6p_p mana_c + nad_c <=> h_c + nadh_c + fruur_c pep_c + manglyc_p --> man6pglyc_c + pyr_c manglyc_e <=> manglyc_p h2o_c + man6pglyc_c --> man6p_c + glyc_dsh_R_c pep_c + man_p --> man6p_c + pyr_c man_e <=> man_p 2mcit_c --> 2mcacn_c + h2o_c micit_c <=> succ_c + pyr_c h2o_c + ppcoa_c + oaa_c --> h_c + coa_c + 2mcit_c ACP_c + malcoa_c <=> coa_c + malACP_c cyan_c + mercppyr_c --> h_c + pyr_c + tcynt_c murein5p5p_p --> ala_dsh_D_p + murein5px4p_p murein5p5p_p --> alaala_p + murein5px3p_p murein5p5p5p_p --> murein5px4px4p_p + 2.0 ala_dsh_D_p h2o_p + murein5px4p_p --> ala_dsh_D_p + murein4px4p_p h2o_p + murein5px4px4p_p --> murein4px4px4p_p + ala_dsh_D_p h2o_p + murein5p5p_p --> murein5p4p_p + ala_dsh_D_p h2o_p + murein5p4p_p --> ala_dsh_D_p + murein4p4p_p h2o_p + murein5p3p_p --> murein4p3p_p + ala_dsh_D_p h2o_p + murein4px4p_p --> murein4p4p_p h2o_p + murein3px4p_p --> murein4p3p_p h2o_p + murein5px4p_p --> murein5p4p_p h2o_p + murein4px4px4p_p --> murein4px4p4p_p mal_dsh_L_c + nad_c <=> h_c + oaa_c + nadh_c mal_dsh_L_c + q8_c --> q8h2_c + oaa_c mal_dsh_L_c + mqn8_c --> oaa_c + mql8_c mal_dsh_L_c + nad_c --> co2_c + pyr_c + nadh_c mal_dsh_L_c + nadp_c --> pyr_c + co2_c + nadph_c h_c + 2mecdp_c + 2.0 flxr_c --> h2mb4p_c + h2o_c + 2.0 flxso_c 2p4c2me_c --> 2mecdp_c + cmp_c h_p + melib_p --> h_c + melib_c h_p + melib_c --> h_c + melib_p melib_e <=> melib_p meoh_e <=> meoh_p meoh_p <=> meoh_c h_c + 2me4p_c + ctp_c --> 4c2me_c + ppi_c atp_c + h2o_c + met_dsh_L_c --> amet_c + ppi_c + pi_c atp_c + met_dsh_D_p + h2o_c --> h_c + met_dsh_D_c + adp_c + pi_c met_dsh_D_e <=> met_dsh_D_p h2o2_c + met_dsh_L_c --> h2o_c + metsox_dsh_S_dsh_L_c h2o2_c + met_dsh_L_c --> h2o_c + metsox_dsh_R_dsh_L_c hcys_dsh_L_c + 5mthf_c --> h_c + met_dsh_L_c + thf_c h2o_c + atp_c + metsox_dsh_S_dsh_L_p --> h_c + metsox_dsh_S_dsh_L_c + adp_c + pi_c metsox_dsh_S_dsh_L_e <=> metsox_dsh_S_dsh_L_p atp_c + h2o_c + metsox_dsh_R_dsh_L_p --> h_c + metsox_dsh_R_dsh_L_c + adp_c + pi_c metsox_dsh_R_dsh_L_e <=> metsox_dsh_R_dsh_L_p metsox_dsh_S_dsh_L_c + trdrd_c --> trdox_c + met_dsh_L_c + h2o_c trdrd_c + metsox_dsh_R_dsh_L_c --> trdox_c + met_dsh_L_c + h2o_c atp_c + trnamet_c + met_dsh_L_c --> amp_c + mettrna_c + ppi_c atp_c + h2o_c + met_dsh_L_p --> h_c + met_dsh_L_c + adp_c + pi_c met_dsh_L_e <=> met_dsh_L_p mg2_p + 2.0 h_c <=> 2.0 h_p + mg2_c mg2_e <=> mg2_p mg2_p --> mg2_c mg2_p + h2o_c + atp_c --> h_c + mg2_c + adp_c + pi_c dhap_c --> mthgxl_c + pi_c mi1p_dsh_D_c + h2o_c --> inost_c + pi_c h2o_c + 2mcacn_c <=> micit_c mincyc_e <=> mincyc_p mincyc_p + h_p --> h_c + mincyc_e minohp_e --> minohp_p h2o_p + murein5px4p_p --> alaala_p + murein3px4p_p h2o_p + murein4p4p_p --> murein4p3p_p + ala_dsh_D_p h2o_p + murein5p5p_p --> alaala_p + murein5p3p_p h2o_p + murein4p3p_p --> ala_dsh_D_p + murein3p3p_p h2o_p + murein5px3p_p --> murein3px3p_p + alaala_p h2o_p + murein3px3p_p --> murein3p3p_p h2o_p + murein5px3p_p --> murein5p3p_p h2o_c + malttr_c --> glc_dsh_D_c + malt_c maltttr_c + h2o_c --> glc_dsh_D_c + malttr_c h2o_c + maltpt_c --> maltttr_c + glc_dsh_D_c h2o_c + malthx_c --> glc_dsh_D_c + maltpt_c h2o_c + malthp_c --> glc_dsh_D_c + malthx_c murein4p4p_p --> 2.0 anhgm4p_p murein4p3p_p --> anhgm4p_p + anhgm3p_p murein3p3p_p --> 2.0 anhgm3p_p murein4px4p4p_p --> murein4px4p_p + anhgm4p_p pi_c + maltpt_c <=> maltttr_c + g1p_c pi_c + malthx_c <=> g1p_c + maltpt_c pi_c + malthp_c <=> g1p_c + malthx_c h_c + mmcoa_dsh_S_c --> ppcoa_c + co2_c mmet_p + h_p --> h_c + mmet_c mmet_e <=> mmet_p succoa_c --> mmcoa_dsh_S_c h_p + mn2_c --> h_c + mn2_p mn2_p --> mn2_c h2o_c + man6p_c --> man_c + pi_c pep_c + mnl_p --> pyr_c + mnl1p_c mnl_e <=> mnl_p mana_c --> 2ddglcn_c + h2o_c h_p + mn2_p --> h_c + mn2_c mn2_e <=> mn2_p nadh_c + iscssh_c + moadamp_c --> iscs_c + amp_c + nad_c + moadcosh_c lipidA_c + ckdo_c --> h_c + cmp_c + kdolipid4_c ckdo_c + kdolipid4_c --> h_c + cmp_c + kdo2lipid4_c phphhlipa_c + ckdo_c --> h_c + cmp_c + kphphhlipa_c atp_c + h2o_c + mobd_p --> h_c + mobd_c + adp_c + pi_c mobd_e <=> mobd_p h_c + ctp_c + moco_c --> mococdp_c + ppi_c 2.0 h_c + mobd_c + mptamp_c --> amp_c + h2o_c + moco_c + cu2_c h_c + gtp_c + moco_c --> mocogdp_c + ppi_c h2o_c + 3mob_c + mlthf_c --> thf_c + 2dhp_c mal_dsh_L_c + o2_c <=> h2o2_c + oaa_c h_c + atp_c + mpt_c --> mptamp_c + ppi_c 2.0 uaagmda_c --> 2.0 h_c + 2.0 udcpdp_c + murein5p5p_p murein5p5p_p + uaagmda_c --> h_c + udcpdp_c + murein5p5p5p_p cu2_c + cpmp_c + 2.0 moadcosh_c --> 5.0 h_c + mpt_c + 2.0 moadcoo_c h_c + atp_c + moadcoo_c --> moadamp_c + ppi_c h_c + msa_c + nadph_c --> nadp_c + 3hpp_c atp_c + h2o_c + mso3_p --> h_c + mso3_c + adp_c + pi_c mso3_e <=> mso3_p h2o_c + 5mta_c --> ade_c + 5mtr_c h2o_c + methf_c <=> h_c + 10fthf_c nadp_c + mlthf_c <=> methf_c + nadph_c 2.0 h_c + nadh_c + mlthf_c --> 5mthf_c + nad_c mdhdhf_c + h2o_c --> mththf_c h2o_c + o2_c + Nmtrp_c --> h2o2_c + fald_c + trp_dsh_L_c n2o_e <=> n2o_p n2o_p <=> n2o_c h2o_c + acg5sa_c --> ac_c + glu5sa_c nac_e <=> nac_p nac_p --> nac_c h2o_c + nad_c --> 2.0 h_c + amp_c + nmn_c h_c + mqn8_c + nadh_c --> mql8_c + nad_c 4.0 h_c + nadh_c + q8_c --> nad_c + 3.0 h_p + q8h2_c 4.0 h_c + mqn8_c + nadh_c --> mql8_c + 3.0 h_p + nad_c nadh_c + 4.0 h_c + 2dmmq8_c --> 2dmmql8_c + nad_c + 3.0 h_p h_c + nadh_c + q8_c --> q8h2_c + nad_c nadh_c + 2dmmq8_c + h_c --> 2dmmql8_c + nad_c nad_c + atp_c --> h_c + adp_c + nadp_c h2o_c + nad_c --> h_c + ncam_c + adprib_c h_c + nadph_c + q8_c --> nadp_c + q8h2_c h_c + mqn8_c + nadph_c --> mql8_c + nadp_c 2dmmq8_c + nadph_c + h_c --> 2dmmql8_c + nadp_c nadp_c + h2o_c --> pi_c + nad_c dnad_c + atp_c + nh4_c --> h_c + amp_c + ppi_c + nad_c nadph_c + nad_c --> nadh_c + nadp_c atp_c + h2o_c + prpp_c + nac_c --> pi_c + nicrnt_c + adp_c + ppi_c 3.0 h_p + 2.0 na1_c --> 3.0 h_c + 2.0 na1_p 2.0 h_p + na1_c --> 2.0 h_c + na1_p h_p + na1_c --> h_c + na1_p na1_e <=> na1_p gdp_c + atp_c <=> gtp_c + adp_c atp_c + udp_c <=> adp_c + utp_c atp_c + cdp_c <=> ctp_c + adp_c atp_c + dtdp_c <=> adp_c + dttp_c atp_c + dgdp_c <=> adp_c + dgtp_c atp_c + dudp_c <=> dutp_c + adp_c atp_c + dcdp_c <=> dctp_c + adp_c atp_c + dadp_c <=> datp_c + adp_c nh4_e <=> nh4_p nh4_p <=> nh4_c h_c + nadh_c + 2.0 no_c --> n2o_c + h2o_c + nad_c atp_c + h2o_c + ni2_c --> h_c + ni2_p + adp_c + pi_c h_p + ni2_c --> h_c + ni2_p ni2_e <=> ni2_p ni2_p --> ni2_c atp_c + ni2_p + h2o_c --> h_c + ni2_c + adp_c + pi_c h_c + atp_c + nmn_c --> nad_c + ppi_c nmn_c + h2o_c --> nh4_c + nicrnt_c h2o_c + nmn_c --> h_c + r5p_c + ncam_c nmn_p --> nmn_c h2o_c + nmn_p --> h_c + r5p_c + ncam_c nmn_e <=> nmn_p ncam_c + h2o_c --> nac_c + nh4_c h_c + atp_c + nicrnt_c <=> ppi_c + dnad_c dmbzid_c + nicrnt_c --> h_c + 5prdmbz_c + nac_c 2.0 h_c + quln_c + prpp_c --> co2_c + nicrnt_c + ppi_c no2_p + h_p <=> h_c + no2_c no2_e <=> no2_p no3_p + q8h2_c --> q8_c + no2_p + h2o_p 2.0 h_c + no3_c + q8h2_c --> no2_c + h2o_c + 2.0 h_p + q8_c mql8_c + no3_p --> no2_p + h2o_p + mqn8_c 2.0 h_c + mql8_c + no3_c --> mqn8_c + h2o_c + 2.0 h_p + no2_c no2_c + no3_p --> no2_p + no3_c no3_e <=> no3_p 2.0 no_c + nadh_c + 2.0 o2_c --> h_c + 2.0 no3_c + nad_c 2.0 no_c + nadph_c + 2.0 o2_c --> h_c + 2.0 no3_c + nadp_c novbcn_e <=> novbcn_p h_p + novbcn_p --> h_c + novbcn_e no_e <=> no_p no_p <=> no_c h2o_c + dump_c --> duri_c + pi_c xmp_c + h2o_c --> xtsn_c + pi_c h2o_p + xmp_p --> pi_p + xtsn_p imp_c + h2o_c --> ins_c + pi_c h2o_p + imp_p --> ins_p + pi_p dimp_c + h2o_c --> din_c + pi_c h2o_p + dimp_p --> din_p + pi_p dump_p + h2o_p --> duri_p + pi_p ump_c + h2o_c --> pi_c + uri_c h2o_p + ump_p --> pi_p + uri_p dcmp_c + h2o_c --> dcyt_c + pi_c dcmp_p + h2o_p --> dcyt_p + pi_p h2o_c + cmp_c --> cytd_c + pi_c cmp_p + h2o_p --> cytd_p + pi_p dtmp_c + h2o_c --> pi_c + thymd_c dtmp_p + h2o_p --> thymd_p + pi_p h2o_c + damp_c --> dad_dsh_2_c + pi_c h2o_p + damp_p --> dad_dsh_2_p + pi_p h2o_c + amp_c --> adn_c + pi_c h2o_p + amp_p --> adn_p + pi_p dgmp_c + h2o_c --> dgsn_c + pi_c h2o_p + dgmp_p --> dgsn_p + pi_p h2o_c + gmp_c --> pi_c + gsn_c h2o_p + gmp_p --> gsn_p + pi_p h2o_c + atp_c --> h_c + adp_c + pi_c itp_c + h2o_c --> h_c + pi_c + idp_c h2o_c + ditp_c --> h_c + didp_c + pi_c xtp_c + h2o_c --> h_c + xdp_c + pi_c h2o_c + gtp_c --> h_c + gdp_c + pi_c h2o_p + gtp_p --> h_p + pi_p + gdp_p h2o_c + ctp_c --> h_c + pi_c + cdp_c h2o_c + dgtp_c --> h_c + ppi_c + dgmp_c h2o_c + ditp_c --> h_c + dimp_c + ppi_c xtp_c + h2o_c --> h_c + xmp_c + ppi_c h2o_c + gtp_c --> h_c + ppi_c + gmp_c h2o_c + dctp_c --> h_c + ppi_c + dcmp_c h2o_c + ctp_c --> h_c + cmp_c + ppi_c h2o_c + datp_c --> h_c + damp_c + ppi_c h2o_c + atp_c --> h_c + amp_c + ppi_c h2o_c + dttp_c --> h_c + ppi_c + dtmp_c utp_c + h2o_c --> h_c + ump_c + ppi_c h2o_c + itp_c --> h_c + imp_c + ppi_c h2o_c + dgtp_c --> dgsn_c + pppi_c gtp_c + h2o_c --> gsn_c + pppi_c 5.0 h_c + 3.0 nadh_c + no2_c --> 2.0 h2o_c + nh4_c + 3.0 nad_c 2.0 h_p + no2_p + 3.0 q8h2_c --> nh4_p + 2.0 h2o_p + 3.0 q8_c 3.0 mql8_c + 2.0 h_p + no2_p --> nh4_p + 3.0 mqn8_c + 2.0 h2o_p atp_c + o16a4colipa_p + h2o_c --> h_c + o16a4colipa_e + adp_c + pi_c o16a4und_p + colipa_p --> h_p + o16a4colipa_p + udcpdp_p 2.0 o16aund_p --> o16a2und_p + h_p + udcpdp_p o16a2und_p + o16aund_p --> o16a3und_p + h_p + udcpdp_p o16aund_p + o16a3und_p --> o16a4und_p + h_p + udcpdp_p ragund_c + accoa_c --> coa_c + aragund_c o16aund_c --> o16aund_p garagund_c + udpgalfur_c --> gfgaragund_c + h_c + udp_c aragund_c + udpg_c --> h_c + udp_c + garagund_c udpg_c + gfgaragund_c --> o16aund_c + h_c + udp_c o2s_e <=> o2s_p o2_e <=> o2_p o2_p <=> o2_c h_c + oaa_c --> pyr_c + co2_c 2obut_c + coa_c --> for_c + ppcoa_c cbp_c + orn_c <=> h_c + citr_dsh_L_c + pi_c ocdca_e --> ocdca_p ocdcea_e --> ocdcea_p octa_e <=> octa_p 5.0 ipdp_c + frdp_c --> 5.0 ppi_c + octdp_c atp_c + h_c + octa_c --> amp_c + octapb_c + ppi_c hgmeACP_c --> h2o_c + egmeACP_c h_c + ogmeACP_c + nadph_c --> nadp_c + hgmeACP_c h_c + malcoame_c + malACP_c --> co2_c + coa_c + ogmeACP_c glu_dsh_L_c + ohpb_c <=> akg_c + phthr_c 2ohph_c + amet_c --> h_c + 2omph_c + ahcys_c amet_c + 2ombzl_c --> h_c + 2ommbl_c + ahcys_c h_c + 3c4mop_c --> 4mop_c + co2_c 2ommbl_c + 0.5 o2_c --> 2omhmbl_c 2ommbl_c + 3.0 h2o_c + nad_c + 2.0 atp_c --> 3.0 h_c + 2omhmbl_c + nadh_c + 2.0 adp_c + 2.0 pi_c h_c + orot5p_c --> co2_c + ump_c 2omph_c + 0.5 o2_c --> 2ombzl_c 2omph_c + 2.0 atp_c + 3.0 h2o_c + nad_c --> 3.0 h_c + nadh_c + 2ombzl_c + 2.0 adp_c + 2.0 pi_c h2o_c + op4en_c --> 4h2opntn_c h_c + 3ophb_c --> co2_c + 2oph_c 2oph_c + 0.5 o2_c --> 2ohph_c 2.0 atp_c + 2oph_c + 3.0 h2o_c + nad_c --> nadh_c + 3.0 h_c + 2ohph_c + 2.0 adp_c + 2.0 pi_c hpmeACP_c --> h2o_c + epmeACP_c h_c + nadph_c + opmeACP_c --> nadp_c + hpmeACP_c h_c + gmeACP_c + malACP_c --> opmeACP_c + co2_c + ACP_c h_c + orn_c --> ptrc_c + co2_c atp_c + h2o_c + orn_p --> h_c + orn_c + adp_c + pi_c orn_e <=> orn_p 2.0 h_p + orot_p --> 2.0 h_c + orot_c orot_e <=> orot_p orot5p_c + ppi_c <=> prpp_c + orot_c oxur_c + pi_c --> cbp_c + oxam_c h_c + oxalcoa_c --> co2_c + forcoa_c nadp_c + 2.0 h2o_c + 2oxpaccoa_c --> 2.0 h_c + nadph_c + 3oxdhscoa_c 3oxdhscoa_c + coa_c --> 23dhacoa_c + accoa_c 2.0 h2o_c + nad_c + 1pyr5c_c --> h_c + nadh_c + glu_dsh_L_c 1pyr5c_c + nadph_c + 2.0 h_c --> pro_dsh_L_c + nadp_c atp_c + h2o_c + pa120_c --> h_c + adp_c + pa120_p + pi_c atp_c + h2o_c + pa140_c --> h_c + pi_c + adp_c + pa140_p h2o_c + pa141_c + atp_c --> h_c + pa141_p + adp_c + pi_c atp_c + h2o_c + pa160_c --> h_c + pa160_p + adp_c + pi_c atp_c + h2o_c + pa161_c --> h_c + pa161_p + pi_c + adp_c pa180_c + h2o_c + atp_c --> h_c + pa180_p + adp_c + pi_c pa181_c + atp_c + h2o_c --> h_c + pa181_p + adp_c + pi_c h_p + pacald_p <=> h_c + pacald_c pacald_e <=> pacald_p h_c + nadph_c + phaccoa_c + o2_c --> nadp_c + h2o_c + rephaccoa_c atp_c + pac_c + coa_c --> amp_c + phaccoa_c + ppi_c atp_c + ala_dsh_B_c + pant_dsh_R_c --> h_c + amp_c + pnto_dsh_R_c + ppi_c h2o_c + pa120_c --> 12dgr120_c + pi_c pa120_p + h2o_p --> 12dgr120_p + pi_p pa140_c + h2o_c --> 12dgr140_c + pi_c h2o_p + pa140_p --> 12dgr140_p + pi_p pa141_c + h2o_c --> 12dgr141_c + pi_c pa141_p + h2o_p --> 12dgr141_p + pi_p pa160_c + h2o_c --> 12dgr160_c + pi_c h2o_p + pa160_p --> 12dgr160_p + pi_p pa161_c + h2o_c --> 12dgr161_c + pi_c pa161_p + h2o_p --> 12dgr161_p + pi_p pa180_c + h2o_c --> 12dgr180_c + pi_c h2o_p + pa180_p --> 12dgr180_p + pi_p h2o_c + pa181_c --> 12dgr181_c + pi_c pa181_p + h2o_p --> 12dgr181_p + pi_p ugmda_c + udcpp_c --> uagmda_c + ump_c paps_c + trdrd_c --> 2.0 h_c + pap_c + trdox_c + so3_c grxrd_c + paps_c --> 2.0 h_c + pap_c + grxox_c + so3_c h2o_c + camp_c --> h_c + amp_c h2o_c + 35cgmp_c --> h_c + gmp_c coa_c + nad_c + pyr_c --> nadh_c + co2_c + accoa_c pdx5p_c + nad_c --> h_c + nadh_c + pydx5p_c pdx5p_c + o2_c --> h2o2_c + pydx5p_c dxyl5p_c + nad_c + phthr_c --> h_c + nadh_c + 2.0 h2o_c + pdx5p_c + co2_c + pi_c h2o_c + pdx5p_c --> pydxn_c + pi_c atp_c + h2o_c + pe120_c --> h_c + adp_c + pe120_p + pi_c atp_c + h2o_c + pe140_c --> h_c + pi_c + pe140_p + adp_c h2o_c + atp_c + pe141_c --> pe141_p + h_c + adp_c + pi_c pe160_c + atp_c + h2o_c --> h_c + adp_c + pi_c + pe160_p atp_c + pe161_c + h2o_c --> h_c + pe161_p + adp_c + pi_c atp_c + pe180_c + h2o_c --> h_c + pe180_p + adp_c + pi_c pe181_c + h2o_c + atp_c --> h_c + pe181_p + adp_c + pi_c peamn_p + h2o_p + o2_p --> nh4_p + pacald_p + h2o2_p peamn_e <=> peamn_p 4per_c + nad_c <=> h_c + nadh_c + ohpb_c pe161_p + lipa_p --> 12dgr161_p + enlipa_p pe181_p + lipa_p --> 12dgr181_p + enlipa_p f6p_c + atp_c --> h_c + adp_c + fdp_c tag6p_dsh_D_c + atp_c --> h_c + adp_c + tagdp_dsh_D_c s7p_c + atp_c --> h_c + adp_c + s17bp_c coa_c + pyr_c --> for_c + accoa_c atp_c + h2o_c + pg120_c --> h_c + adp_c + pg120_p + pi_c atp_c + h2o_c + pg140_c --> h_c + pi_c + pg140_p + adp_c h2o_c + atp_c + pg141_c --> pg141_p + h_c + adp_c + pi_c pg160_c + atp_c + h2o_c --> h_c + adp_c + pi_c + pg160_p atp_c + h2o_c + pg161_c --> h_c + pg161_p + adp_c + pi_c atp_c + pg180_c + h2o_c --> h_c + pg180_p + adp_c + pi_c pg181_c + h2o_c + atp_c --> h_c + pg181_p + adp_c + pi_c gam1p_c <=> gam6p_c nad_c + 3pg_c --> h_c + nadh_c + 3php_c g6p_c <=> f6p_c 3pg_c + atp_c <=> 13dpg_c + adp_c h2o_c + 6pgl_c --> h_c + 6pgc_c 2pglyc_c + h2o_c --> glyclt_c + pi_c 2pg_c <=> 3pg_c g1p_c <=> g6p_c atp_c + h2o_c + pgp120_c --> h_c + adp_c + pi_c + pgp120_p atp_c + h2o_c + pgp140_c --> h_c + adp_c + pi_c + pgp140_p atp_c + h2o_c + pgp141_c --> h_c + pi_c + adp_c + pgp141_p pgp160_c + h2o_c + atp_c --> h_c + pgp160_p + adp_c + pi_c pgp161_c + atp_c + h2o_c --> h_c + adp_c + pi_c + pgp161_p atp_c + pgp180_c + h2o_c --> h_c + pgp180_p + adp_c + pi_c atp_c + pgp181_c + h2o_c --> h_c + pgp181_p + adp_c + pi_c pgp120_c + h2o_c --> pg120_c + pi_c h2o_p + pgp120_p --> pg120_p + pi_p pgp140_c + h2o_c --> pg140_c + pi_c pgp140_p + h2o_p --> pg140_p + pi_p pgp141_c + h2o_c --> pg141_c + pi_c h2o_p + pgp141_p --> pg141_p + pi_p pgp160_c + h2o_c --> pg160_c + pi_c h2o_p + pgp160_p --> pg160_p + pi_p pgp161_c + h2o_c --> pg161_c + pi_c h2o_p + pgp161_p --> pg161_p + pi_p pgp180_c + h2o_c --> pg180_c + pi_c h2o_p + pgp180_p --> pg180_p + pi_p pgp181_c + h2o_c --> pg181_c + pi_c h2o_p + pgp181_p --> pg181_p + pi_p glyc3p_c + cdpdddecg_c --> h_c + pgp120_c + cmp_c glyc3p_c + cdpdtdecg_c --> h_c + pgp140_c + cmp_c cdpdtdec7eg_c + glyc3p_c --> h_c + cmp_c + pgp141_c glyc3p_c + cdpdhdecg_c --> h_c + pgp160_c + cmp_c cdpdhdec9eg_c + glyc3p_c --> h_c + cmp_c + pgp161_c glyc3p_c + cdpdodecg_c --> h_c + pgp180_c + cmp_c cdpdodec11eg_c + glyc3p_c --> h_c + cmp_c + pgp181_c atp_c + h2o_c + pheme_c --> h_c + pheme_p + adp_c + pi_c pheme_p --> pheme_e phe_dsh_L_c + akg_c <=> glu_dsh_L_c + phpyr_c atp_c + trnaphe_c + phe_dsh_L_c --> amp_c + ppi_c + phetrna_c phe_dsh_L_p + h_p <=> h_c + phe_dsh_L_c phe_dsh_L_e <=> phe_dsh_L_p 6.0 h2o_p + minohp_p --> inost_p + 6.0 pi_p pi_p + h_p <=> h_c + pi_c pi_e <=> pi_p atp_c + h2o_c + pi_p --> h_c + adp_c + 2.0 pi_c h2o_p + pa120_p --> 2ddecg3p_p + ddca_p h2o_p + pa140_p --> ttdca_p + 2tdecg3p_p h2o_p + pa141_p --> 2tdec7eg3p_p + ttdcea_p h2o_p + pa160_p --> hdca_p + 2hdecg3p_p h2o_p + pa161_p --> 2hdec9eg3p_p + hdcea_p h2o_p + pa180_p --> ocdca_p + 2odecg3p_p pa181_p + h2o_p --> ocdcea_p + 2odec11eg3p_p h2o_p + pe120_p --> 2agpe120_p + h_p + ddca_p h2o_p + pe140_p --> 2agpe140_p + ttdca_p + h_p pe141_p + h2o_p --> ttdcea_p + h_p + 2agpe141_p h2o_p + pe160_p --> 2agpe160_p + hdca_p + h_p pe161_p + h2o_p --> 2agpe161_p + h_p + hdcea_p h2o_p + pe180_p --> 2agpe180_p + ocdca_p + h_p pe181_p + h2o_p --> ocdcea_p + 2agpe181_p + h_p pg120_p + h2o_p --> 2agpg120_p + h_p + ddca_p h2o_p + pg140_p --> 2agpg140_p + ttdca_p + h_p pg141_p + h2o_p --> 2agpg141_p + h_p + ttdcea_p h2o_p + pg160_p --> 2agpg160_p + hdca_p + h_p pg161_p + h2o_p --> 2agpg161_p + h_p + hdcea_p h2o_p + pg180_p --> 2agpg180_p + ocdca_p + h_p pg181_p + h2o_p --> ocdcea_p + 2agpg181_p + h_p pa120_p + h2o_p --> 1ddecg3p_p + h_p + ddca_p h2o_p + pa140_p --> 1tdecg3p_p + ttdca_p + h_p h2o_p + pa141_p --> ttdcea_p + h_p + 1tdec7eg3p_p h2o_p + pa160_p --> 1hdecg3p_p + hdca_p + h_p h2o_p + pa161_p --> hdcea_p + h_p + 1hdec9eg3p_p h2o_p + pa180_p --> 1odecg3p_p + ocdca_p + h_p pa181_p + h2o_p --> ocdcea_p + 1odec11eg3p_p + h_p h2o_p + pe120_p --> 1agpe120_p + h_p + ddca_p h2o_p + pe140_p --> 1agpe140_p + ttdca_p + h_p pe141_p + h2o_p --> 1agpe141_p + h_p + ttdcea_p h2o_p + pe160_p --> 1agpe160_p + hdca_p + h_p pe161_p + h2o_p --> 1agpe161_p + h_p + hdcea_p h2o_p + pe180_p --> 1agpe180_p + ocdca_p + h_p pe181_p + h2o_p --> ocdcea_p + 1agpe181_p + h_p pg120_p + h2o_p --> ddca_p + h_p + 1agpg120_p h2o_p + pg140_p --> 1agpg140_p + ttdca_p + h_p h2o_p + pg141_p --> ttdcea_p + h_p + 1agpg141_p h2o_p + pg160_p --> 1agpg160_p + hdca_p + h_p h2o_p + pg161_p --> hdcea_p + h_p + 1agpg161_p h2o_p + pg180_p --> 1agpg180_p + ocdca_p + h_p pg181_p + h2o_p --> ocdcea_p + 1agpg181_p + h_p man1p_c <=> man6p_c 5aprbu_c + h2o_c --> 4r5au_c + pi_c pmeACP_c + h2o_c --> meoh_c + pimACP_c 4ampm_c + atp_c --> 2mahmp_c + adp_c pnto_dsh_R_c + atp_c --> h_c + 4ppan_c + adp_c na1_p + pnto_dsh_R_p --> na1_c + pnto_dsh_R_c pnto_dsh_R_e <=> pnto_dsh_R_p nadh_c + poaac_c --> h2o_c + nad_c + 3amac_c coa_c + pyr_c + 2.0 flxso_c <=> h_c + co2_c + accoa_c + 2.0 flxr_c h2o_c + pyr_c + q8_c --> ac_c + co2_c + q8h2_c ppi_c + h2o_c --> h_c + 2.0 pi_c h2o_c + pppi_c --> h_c + pi_c + ppi_c adp_c + ppap_c <=> ppa_c + atp_c ppal_e <=> ppal_p ppal_c <=> ppal_p na1_p + ppa_p --> ppa_c + na1_c ppa_e <=> ppa_p 2.0 5aop_c --> 2.0 h2o_c + h_c + ppbng_c co2_c + h2o_c + pep_c --> h_c + pi_c + oaa_c h_c + 4ppcys_c --> pan4p_c + co2_c atp_c + oaa_c --> adp_c + pep_c + co2_c succ_c + ppcoa_c --> ppa_c + succoa_c ppgpp_c + h2o_c --> gdp_c + ppi_c atp_c + ppi_c <=> pppi_c + adp_c atp_c + pi_c <=> adp_c + ppi_c r1p_c <=> r5p_c 2dr1p_c <=> 2dr5p_c 4ppan_c + cys_dsh_L_c + ctp_c --> h_c + cmp_c + 4ppcys_c + ppi_c pphn_c + nad_c --> 34hpp_c + co2_c + nadh_c h_c + pphn_c --> h2o_c + co2_c + phpyr_c pppg9_c + 1.5 o2_c --> 3.0 h2o_c + ppp9_c pppg9_c + 3.0 fum_c --> ppp9_c + 3.0 succ_c h_c + nadh_c + pppn_c + o2_c --> nad_c + cechddd_c pppn_p + h_p <=> h_c + pppn_c pppn_e <=> pppn_p atp_c + h2o_c + pyr_c --> amp_c + 2.0 h_c + pep_c + pi_c h2o_p + ppt_p --> h2_p + pi_p ppt_e <=> ppt_p atp_c + pram_c + gly_c <=> h_c + adp_c + pi_c + gar_c atp_c + fpram_c --> 2.0 h_c + air_c + adp_c + pi_c pran_c --> 2cpr5p_c h2o_c + prbamp_c --> prfp_c asp_dsh_L_c + atp_c + 5aizc_c --> h_c + 25aics_c + adp_c + pi_c prbatp_c + h2o_c --> h_c + prbamp_c + ppi_c atp_c + h2o_c + fgam_c + gln_dsh_L_c --> h_c + glu_dsh_L_c + fpram_c + adp_c + pi_c prfp_c <=> prlp_c fad_c + pro_dsh_L_c --> 1pyr5c_c + h_c + fadh2_c atp_c + h2o_c + progly_p --> h_c + progly_c + adp_c + pi_c progly_e <=> progly_p atp_c + pro_dsh_L_c + trnapro_c --> amp_c + protrna_c + ppi_c h2o_c + pro_dsh_L_p + atp_c --> pro_dsh_L_c + h_c + adp_c + pi_c pro_dsh_L_p + h_p <=> pro_dsh_L_c + h_c pro_dsh_L_p + na1_p --> pro_dsh_L_c + na1_c pro_dsh_L_e <=> pro_dsh_L_p r5p_c + atp_c <=> amp_c + h_c + prpp_c psclys_p + h_p --> h_c + psclys_c psclys_e <=> psclys_p skm5p_c + pep_c <=> pi_c + 3psme_c ps120_c + h_c --> pe120_c + co2_c h_c + ps140_c --> pe140_c + co2_c ps141_c + h_c --> pe141_c + co2_c h_c + ps160_c --> pe160_c + co2_c ps161_c + h_c --> pe161_c + co2_c h_c + ps180_c --> pe180_c + co2_c ps181_c + h_c --> pe181_c + co2_c 3php_c + glu_dsh_L_c --> pser_dsh_L_c + akg_c pser_dsh_L_e <=> pser_dsh_L_p pser_dsh_L_c + h2o_c --> pi_c + ser_dsh_L_c h2o_p + pser_dsh_L_p --> pi_p + ser_dsh_L_p ser_dsh_L_c + cdpdddecg_c --> ps120_c + h_c + cmp_c ser_dsh_L_c + cdpdtdecg_c --> h_c + ps140_c + cmp_c ser_dsh_L_c + cdpdtdec7eg_c --> h_c + cmp_c + ps141_c ser_dsh_L_c + cdpdhdecg_c --> h_c + ps160_c + cmp_c ser_dsh_L_c + cdpdhdec9eg_c --> ps161_c + h_c + cmp_c ser_dsh_L_c + cdpdodecg_c --> ps180_c + h_c + cmp_c ser_dsh_L_c + cdpdodec11eg_c --> ps181_c + h_c + cmp_c pi_c + ppcoa_c --> coa_c + ppap_c pi_c + accoa_c <=> actp_c + coa_c h2o_p + thrp_p --> pi_p + thr_dsh_L_p h_c + atp_c + pan4p_c --> dpcoa_c + ppi_c orn_c + ptrc_p <=> ptrc_c + orn_p ptrc_c + akg_c --> glu_dsh_L_c + 4abutn_c ptrc_p + atp_c + h2o_c --> h_c + ptrc_c + adp_c + pi_c h_p + ptrc_p --> h_c + ptrc_c ptrc_e <=> ptrc_p adn_c + pi_c <=> ade_c + r1p_c dad_dsh_2_c + pi_c <=> 2dr1p_c + ade_c pi_c + gsn_c <=> gua_c + r1p_c pi_c + dgsn_c <=> 2dr1p_c + gua_c ins_c + pi_c <=> hxan_c + r1p_c pi_c + din_c <=> 2dr1p_c + hxan_c xtsn_c + pi_c <=> r1p_c + xan_c h2o_c + o2_c + pyam5p_c --> nh4_c + pydx5p_c + h2o2_c pydam_c + atp_c --> pyam5p_c + h_c + adp_c pydam_e <=> pydam_p pydam_p --> pydam_c pydx_c + atp_c --> h_c + pydx5p_c + adp_c pydxn_c + atp_c --> pdx5p_c + h_c + adp_c pydxn_e <=> pydxn_p pydxn_p --> pydxn_c pydx5p_c + h2o_c --> pi_c + pydx_c pydx_e <=> pydx_p pydx_p --> pydx_c h_c + adp_c + pep_c --> pyr_c + atp_c uri_c + pi_c <=> ura_c + r1p_c h_c + nadh_c + o2_c + ura_c --> uracp_c + nad_c h_p + pyr_p <=> h_c + pyr_c pyr_e <=> pyr_p q8h2_c + 2.0 o2_c --> 2.0 o2s_c + q8_c + 2.0 h_c 2.0 o2_c + mql8_c --> 2.0 o2s_c + mqn8_c + 2.0 h_c quin_e <=> quin_p quin_p <=> quin_c nad_c + quin_c <=> 2.0 h_c + nadh_c + 3dhq_c iasp_c + dhap_c --> 2.0 h2o_c + quln_c + pi_c atp_c + r15bp_c --> prpp_c + adp_c r1p_c + atp_c --> h_c + r15bp_c + adp_c h2o_c + r5p_c --> pi_c + rib_dsh_D_c r5p_p + h2o_p --> rib_dsh_D_p + pi_p r5p_e <=> r5p_p ribflv_c + atp_c --> h_c + fmn_c + adp_c 4r5au_c + db4p_c --> dmlz_c + 2.0 h2o_c + pi_c 2.0 dmlz_c --> ribflv_c + 4r5au_c rib_dsh_D_c + atp_c --> h_c + adp_c + r5p_c rbl_dsh_L_c + atp_c --> ru5p_dsh_L_c + h_c + adp_c ru5p_dsh_L_c <=> xu5p_dsh_D_c rephaccoa_c <=> 2oxpaccoa_c rfamp_e <=> rfamp_p rfamp_p + h_p --> h_c + rfamp_e kphphhlipa_c + dtdprmn_c --> h_c + dtdp_c + icolipa_c rhcys_c --> hcys_dsh_L_c + dhptd_c atp_c + rib_dsh_D_p + h2o_c --> h_c + pi_c + adp_c + rib_dsh_D_c rib_dsh_D_e <=> rib_dsh_D_p rmn_c <=> rml_c rml_c + atp_c --> h_c + adp_c + rml1p_c rmn_e <=> rmn_p rmn_p + h_p --> h_c + rmn_c rml1p_c <=> dhap_c + lald_dsh_L_c adp_c + trdrd_c --> trdox_c + h2o_c + dadp_c adp_c + grxrd_c --> dadp_c + h2o_c + grxox_c gdp_c + trdrd_c --> trdox_c + h2o_c + dgdp_c gdp_c + grxrd_c --> dgdp_c + h2o_c + grxox_c trdrd_c + cdp_c --> trdox_c + dcdp_c + h2o_c cdp_c + grxrd_c --> dcdp_c + h2o_c + grxox_c trdrd_c + udp_c --> trdox_c + dudp_c + h2o_c udp_c + grxrd_c --> dudp_c + h2o_c + grxox_c 2.0 h_c + atp_c + 2.0 flxr_c --> h2o_c + datp_c + 2.0 flxso_c 2.0 h_c + gtp_c + 2.0 flxr_c --> h2o_c + dgtp_c + 2.0 flxso_c 2.0 h_c + ctp_c + 2.0 flxr_c --> h2o_c + dctp_c + 2.0 flxso_c utp_c + 2.0 h_c + 2.0 flxr_c --> h2o_c + 2.0 flxso_c + dutp_c ru5p_dsh_D_c <=> xu5p_dsh_D_c r5p_c <=> ru5p_dsh_D_c 5prdmbz_c + h2o_c --> pi_c + rdmbzi_c atp_c + sufbcd_c + h2o_c + sufsesh_c + 2fe1s_c --> 5.0 h_c + sufse_c + sufbcd_dsh_2fe2s_c + adp_c + pi_c sufbcd_c + atp_c + h2o_c + 2.0 sufsesh_c + 2.0 fe2_c + fadh2_c --> 7.0 h_c + 2.0 sufse_c + sufbcd_dsh_2fe2s_c + fad_c + adp_c + pi_c fadh2_c + atp_c + h2o_c + sufbcd_dsh_2fe2s_c + 2.0 sufsesh_c + 2.0 fe2_c --> 7.0 h_c + 2.0 sufse_c + fad_c + adp_c + pi_c + sufbcd_dsh_2fe2s2_c 4.0 h_c + sufbcd_dsh_2fe2s_c --> 2fe2s_c + sufbcd_c 2.0 h_c + sufbcd_dsh_2fe2s2_c + fadh2_c --> sufbcd_dsh_4fe4s_c + fad_c 4.0 h_c + sufbcd_dsh_4fe4s_c --> 4fe4s_c + sufbcd_c s7p_c --> gmhep7p_c 2.0 h_c + 2.0 h2o_c + sucarg_c --> 2.0 nh4_c + co2_c + sucorn_c atp_c + gtp_c + h2o_c + so4_c --> gdp_c + aps_c + ppi_c + pi_c sarcs_c + h2o_c + o2_c --> fald_c + h2o2_c + gly_c nad_c + sbt6p_c <=> h_c + nadh_c + f6p_c sbt_dsh_D_p + pep_c --> pyr_c + sbt6p_c sbt_dsh_D_e <=> sbt_dsh_D_p sufse_c + cys_dsh_L_c --> ala_dsh_L_c + sufsesh_c sl26da_c + h2o_c --> 26dap_dsh_LL_c + succ_c sl26da_c + akg_c <=> glu_dsh_L_c + sl2a6o_c sertrna_lb_sec_rb__c + selnp_c --> h_c + sectrna_c + pi_c 2.0 h_c + slnt_c + 4.0 gthrd_c --> gthox_c + 3.0 h2o_c + dgslnt_c h_c + nadph_c + dgslnt_c --> nadp_c + gslnt_c + gthrd_c nadph_c + gslnt_c --> gthrd_c + nadp_c + seln_c atp_c + h2o_c + seln_c --> amp_c + pi_c + selnp_c mql8_c + sel_c --> h2o_c + slnt_c + mqn8_c sel_e <=> sel_p 2.0 h_p + sel_p --> 2.0 h_c + sel_c ichor_c + h_c + akg_c --> 2sephchc_c + co2_c ser_dsh_L_c + h_c + atp_c <=> seramp_c + ppi_c ser_dsh_L_c + accoa_c <=> coa_c + acser_c ser_dsh_D_c --> pyr_c + nh4_c ser_dsh_L_c --> nh4_c + pyr_c atp_c + ser_dsh_L_c + trnaser_c --> sertrna_c + ppi_c + amp_c atp_c + ser_dsh_L_c + trnasecys_c --> sertrna_lb_sec_rb__c + ppi_c + amp_c h_p + ser_dsh_L_p <=> h_c + ser_dsh_L_c na1_p + ser_dsh_L_p --> ser_dsh_L_c + na1_c ser_dsh_L_e <=> ser_dsh_L_p h2o_c + Sfglutth_c --> h_c + gthrd_c + for_c sucglu_c + h2o_c --> glu_dsh_L_c + succ_c sucgsa_c + h2o_c + nad_c --> 2.0 h_c + sucglu_c + nadh_c 2sephchc_c --> 2shchc_c + pyr_c dscl_c + nad_c --> h_c + scl_c + nadh_c scl_c + fe2_c --> 3.0 h_c + sheme_c nadph_c + 3dhsk_c + h_c <=> skm_c + nadp_c skm_c + atp_c --> h_c + adp_c + skm5p_c suchms_c + cys_dsh_L_c --> h_c + succ_c + cyst_dsh_L_c skm_p + h_p --> skm_c + h_c skm_e <=> skm_p slnt_e <=> slnt_p h_p + slnt_p --> h_c + slnt_c so2_e <=> so2_p so2_p <=> so2_c so3_e <=> so3_p so4_p + h_p --> h_c + so4_c so4_e <=> so4_p sucorn_c + akg_c --> glu_dsh_L_c + sucgsa_c spmd_c + accoa_c --> h_c + coa_c + N1aspmd_c spmd_c + accoa_c --> h_c + coa_c + n8aspmd_c atp_c + h2o_c + spmd_p --> h_c + pi_c + adp_c + spmd_c h_p + spmd_c --> h_c + spmd_p spmd_e <=> spmd_p ptrc_c + ametam_c --> h_c + 5mta_c + spmd_c 2.0 o2s_c + 2.0 h_c --> h2o2_c + o2_c 2.0 h_p + 2.0 o2s_p --> o2_p + h2o2_p h2o_c + sucsal_c + nad_c --> 2.0 h_c + nadh_c + succ_c nadp_c + h2o_c + sucsal_c --> 2.0 h_c + nadph_c + succ_c succ_c + asp_dsh_L_p --> asp_dsh_L_c + succ_p atp_c + coa_c + sucbz_c --> amp_c + ppi_c + sbzcoa_c 2shchc_c --> h2o_c + sucbz_c succ_p + 2.0 h_p --> 2.0 h_c + succ_c succ_p + 3.0 h_p --> 3.0 h_c + succ_c h_p + succ_c --> h_c + succ_p succ_e <=> succ_p q8_c + succ_c --> q8h2_c + fum_c succ_c + fum_p --> fum_c + succ_p succ_c + mal_dsh_L_p --> mal_dsh_L_c + succ_p atp_c + coa_c + succ_c <=> pi_c + adp_c + succoa_c sucr_e <=> sucr_p succ_c + tartr_dsh_D_p --> tartr_dsh_D_c + succ_p pep_c + sucr_p --> suc6p_c + pyr_c sulfac_p + h2o_c + atp_c --> h_c + sulfac_c + adp_c + pi_c sulfac_e <=> sulfac_p 5.0 h_c + 3.0 nadph_c + so3_c --> 3.0 nadp_c + 3.0 h2o_c + h2s_c atp_c + h2o_c + so4_p --> h_c + adp_c + so4_c + pi_c tdec2eACP_c <=> cdec3eACP_c altrn_c + nad_c <=> h_c + tagur_c + nadh_c s7p_c + g3p_c <=> e4p_c + f6p_c tartr_dsh_L_c --> h2o_c + oaa_c tartr_dsh_D_e <=> tartr_dsh_D_p succ_c + tartr_dsh_L_p <=> tartr_dsh_L_c + succ_p tartr_dsh_L_e <=> tartr_dsh_L_p 3.0 h_p + tartr_dsh_D_p --> 3.0 h_c + tartr_dsh_D_c o2_c + taur_c + akg_c --> h_c + co2_c + so3_c + succ_c + aacald_c atp_c + h2o_c + taur_p --> h_c + taur_c + adp_c + pi_c taur_e <=> taur_p tcynt_e <=> tcynt_p h2o_c + thmpp_c --> thmmp_c + pi_c + h_c dtdp4addg_c + accoa_c --> h_c + coa_c + dtdp4aaddg_c dtdp4d6dg_c + glu_dsh_L_c --> dtdp4addg_c + akg_c dtdp4d6dg_c --> dtdp4d6dm_c h_c + dtdp4d6dm_c + nadph_c --> dtdprmn_c + nadp_c dtdpglu_c --> h2o_c + dtdp4d6dg_c lipidAds_c + atp_c --> h_c + adp_c + lipidA_c dsbdrd_c + dsbcox_p --> dsbdox_c + dsbcrd_p dsbdrd_c + dsbgox_p --> dsbdox_c + dsbgrd_p tagdp_dsh_D_c <=> dhap_c + g3p_c nadp_c + nadh_c + 2.0 h_p --> 2.0 h_c + nadph_c + nad_c h2o_c + succoa_c + thdp_c --> sl2a6o_c + coa_c h2o_c + methf_c --> h_c + 5fthf_c trdrd_c + h2o2_c --> trdox_c + 2.0 h2o_c thymd_p + h_p --> h_c + thymd_c thymd_p + h_p <=> h_c + thymd_c thymd_e <=> thymd_p atp_c + h2o_c + thm_p --> h_c + adp_c + thm_c + pi_c thm_e <=> thm_p athr_dsh_L_c --> gly_c + acald_c thr_dsh_L_c --> gly_c + acald_c thr_dsh_L_c + nad_c --> h_c + 2aobut_c + nadh_c thr_dsh_L_c --> 2obut_c + nh4_c thrp_e <=> thrp_p phom_c + h2o_c --> pi_c + thr_dsh_L_c atp_c + trnathr_c + thr_dsh_L_c --> thrtrna_c + ppi_c + amp_c atp_c + h2o_c + thr_dsh_L_p --> h_c + pi_c + adp_c + thr_dsh_L_c h_p + thr_dsh_L_c --> h_c + thr_dsh_L_p thr_dsh_L_p + h_p <=> h_c + thr_dsh_L_c na1_p + thr_dsh_L_p --> thr_dsh_L_c + na1_c thr_dsh_L_e <=> thr_dsh_L_p h_p + thym_c --> thym_p + h_c thym_e <=> thym_p nadph_c + h_c + iscssh_c + dhgly_c + atp_c + dxyl5p_c --> iscs_c + nadp_c + 2.0 h2o_c + 4mpetz_c + co2_c + ppi_c + amp_c xu5p_dsh_D_c + r5p_c <=> g3p_c + s7p_c xu5p_dsh_D_c + e4p_c <=> g3p_c + f6p_c h_c + mql8_c + tmao_c --> mqn8_c + h2o_c + tma_c mql8_c + h_p + tmao_p --> mqn8_c + tma_p + h2o_p 2dmmql8_c + h_c + tmao_c --> h2o_c + tma_c + 2dmmq8_c 2dmmql8_c + h_p + tmao_p --> tma_p + h2o_p + 2dmmq8_c tmao_e <=> tmao_p tma_e <=> tma_p thymd_c + atp_c --> h_c + dtmp_c + adp_c thymd_c + pi_c <=> 2dr1p_c + thym_c mlthf_c + dump_c --> dhf_c + dtmp_c thm_c + atp_c --> thmmp_c + h_c + adp_c thmmp_c + atp_c --> thmpp_c + adp_c 4mpetz_c + h_c + 2mahmp_c --> thmmp_c + ppi_c dhap_c <=> g3p_c atp_c + dpcoa_c --> 2tpr3dpcoa_c + ade_c trdox_c + nadph_c + h_c --> nadp_c + trdrd_c tre6p_c + h2o_c --> g6p_c + glc_dsh_D_c h2o_c + tre6p_c --> tre_c + pi_c udpg_c + g6p_c --> h_c + tre6p_c + udp_c h2o_c + tre_c --> 2.0 glc_dsh_D_c h2o_p + tre_p --> 2.0 glc_dsh_D_p pep_c + tre_p --> pyr_c + tre6p_c tre_e <=> tre_p h2o_c + trp_dsh_L_c <=> indole_c + pyr_c + nh4_c 3ig3p_c + ser_dsh_L_c --> trp_dsh_L_c + g3p_c + h2o_c ser_dsh_L_c + indole_c --> h2o_c + trp_dsh_L_c 3ig3p_c --> g3p_c + indole_c atp_c + trp_dsh_L_c + trnatrp_c --> amp_c + trptrna_c + ppi_c trp_dsh_L_p + h_p <=> h_c + trp_dsh_L_c trp_dsh_L_e <=> trp_dsh_L_p h_c + nadh_c + 2h3oppan_c <=> glyc_dsh_R_c + nad_c tsul_p + h2o_c + atp_c --> h_c + adp_c + tsul_c + pi_c tsul_e <=> tsul_p ttdca_e --> ttdca_p ttdcea_e --> ttdcea_p ttrcyc_e <=> ttrcyc_p ttrcyc_p + h_p --> h_c + ttrcyc_e atp_c + h2o_c + tungs_p --> h_c + tungs_c + adp_c + pi_c tungs_e <=> tungs_p tym_e <=> tym_p amet_c + nadph_c + tyr_dsh_L_c --> h_c + nadp_c + dad_dsh_5_c + 4crsol_c + dhgly_c + met_dsh_L_c tym_p + o2_p + h2o_p --> 4hoxpacd_p + nh4_p + h2o2_p h2o_p + tyrp_p --> pi_p + tyr_dsh_L_p tyrp_e <=> tyrp_p akg_c + tyr_dsh_L_c <=> 34hpp_c + glu_dsh_L_c atp_c + trnatyr_c + tyr_dsh_L_c --> amp_c + tyrtrna_c + ppi_c tyr_dsh_L_p + h_p <=> h_c + tyr_dsh_L_c tyr_dsh_L_e <=> tyr_dsh_L_p thmpp_c + adp_c + h_c --> athtp_c + pi_c u3hga_c + 3hmrsACP_c --> ACP_c + h_c + u23ga_c 26dap_dsh_M_c + atp_c + uamag_c --> h_c + pi_c + ugmd_c + adp_c h2o_p + udpacgal_p --> ump_p + 2.0 h_p + acgal1p_p h2o_p + uacgam_p --> acgam1p_p + ump_p + 2.0 h_p uacgam_e <=> uacgam_p uacmam_c + h2o_c + 2.0 nad_c --> 3.0 h_c + 2.0 nadh_c + uacmamu_c uacgam_c <=> uacmam_c uacgam_c + 3hmrsACP_c <=> ACP_c + u3aga_c uacgam_c + pep_c --> pi_c + uaccg_c acgam1p_c + utp_c + h_c --> uacgam_c + ppi_c uagmda_c + uacgam_c --> udp_c + h_c + uaagmda_c atp_c + glu_dsh_D_c + uama_c --> pi_c + h_c + adp_c + uamag_c uamr_c + ala_dsh_L_c + atp_c --> h_c + adp_c + uama_c + pi_c h_c + uaccg_c + nadph_c --> nadp_c + uamr_c h2o_c + udcpdp_c --> h_c + pi_c + udcpp_c 8.0 ipdp_c + frdp_c --> 8.0 ppi_c + udcpdp_c h2o_p + udcpdp_p --> udcpp_p + h_p + pi_p udcpp_p --> udcpp_c udpacgal_e <=> udpacgal_p udpg_c <=> udpgal_c udpgal_c --> udpgalfur_c h2o_p + udpgal_p --> gal1p_p + ump_p + 2.0 h_p udpgal_e <=> udpgal_p udpg_c + h2o_c + 2.0 nad_c --> 3.0 h_c + 2.0 nadh_c + udpglcur_c udpglcur_c + nad_c --> co2_c + udpLa4o_c + nadh_c udpglcur_e <=> udpglcur_p h2o_p + udpg_p --> ump_p + 2.0 h_p + g1p_p udpg_e <=> udpg_p glu_dsh_L_c + udpLa4o_c <=> akg_c + udpLa4n_c h2o_p + udpglcur_p --> ump_p + 2.0 h_p + glcur1p_p udpg_c + gal1p_c <=> g1p_c + udpgal_c 2.0 h_c + h2o_c + urdglyc_c --> 2.0 nh4_c + co2_c + glx_c alaala_c + atp_c + ugmd_c --> h_c + ugmda_c + pi_c + adp_c u3aga_c + h2o_c --> ac_c + u3hga_c udpLa4n_c + 10fthf_c --> h_c + thf_c + udpLa4fn_c uLa4n_c --> uLa4n_p atp_c + LalaDgluMdap_c + uamr_c --> h_c + pi_c + adp_c + ugmd_c h2o_c + um4p_c --> ala_dsh_D_c + ugmd_c uamr_c + LalaDgluMdapDala_c + atp_c --> h_c + um4p_c + adp_c + pi_c atp_c + ump_c <=> udp_c + adp_c ump_e <=> ump_p uLa4fn_c + h2o_c --> for_c + uLa4n_c udpLa4fn_c + udcpp_c --> uLa4fn_c + udp_c uppg3_c + 2.0 amet_c --> h_c + dscl_c + 2.0 ahcys_c hmbil_c --> h2o_c + uppg3_c 4.0 h_c + uppg3_c --> cpppg3_c + 4.0 co2_c ura_c + prpp_c --> ppi_c + ump_c h2o_c + uracp_c --> h_c + poaac_c + cbm_c h_p + ura_p --> h_c + ura_c h_p + ura_p <=> h_c + ura_c ura_e <=> ura_p urdglyc_c + nad_c --> h_c + oxur_c + nadh_c urea_e <=> urea_p urea_p <=> urea_c urate_c + 2.0 h2o_c + o2_c --> co2_c + h2o2_c + alltn_c h2o_c + uri_c --> ura_c + rib_dsh_D_c uri_c + gtp_c --> h_c + ump_c + gdp_c uri_p + h_p --> h_c + uri_c uri_p + h_p <=> h_c + uri_c uri_e <=> uri_p u23ga_c + h2o_c --> 2.0 h_c + lipidX_c + ump_c val_dsh_L_c + akg_c <=> glu_dsh_L_c + 3mob_c atp_c + trnaval_c + val_dsh_L_c --> amp_c + valtrna_c + ppi_c atp_c + h2o_c + val_dsh_L_p --> h_c + val_dsh_L_c + adp_c + pi_c h_p + val_dsh_L_p <=> h_c + val_dsh_L_c val_dsh_L_e <=> val_dsh_L_p ala_dsh_L_c + 3mob_c <=> pyr_c + val_dsh_L_c 2.0 h_c + tungs_c + mptamp_c --> amp_c + wco_c + h2o_c + cu2_c xu5p_dsh_L_c --> ru5p_dsh_L_c h2o_c + xan_c + nad_c --> h_c + nadh_c + urate_c xan_p + h_p --> h_c + xan_c xan_e <=> xan_p xan_p <=> xan_c xmp_e <=> xmp_p xan_c + prpp_c --> ppi_c + xmp_c xtsn_c + h2o_c --> rib_dsh_D_c + xan_c xtsn_p + h_p <=> h_c + xtsn_c xtsn_e <=> xtsn_p xyl_dsh_D_c <=> xylu_dsh_D_c glc_dsh_D_c <=> fru_c xylu_dsh_D_c + atp_c --> h_c + adp_c + xu5p_dsh_D_c xylu_dsh_L_c + atp_c --> h_c + adp_c + xu5p_dsh_L_c h_p + xylu_dsh_L_p --> h_c + xylu_dsh_L_c xylu_dsh_L_e <=> xylu_dsh_L_p xyl_dsh_D_p + h2o_c + atp_c --> h_c + xyl_dsh_D_c + adp_c + pi_c xyl_dsh_D_p + h_p --> h_c + xyl_dsh_D_c xyl_dsh_D_e <=> xyl_dsh_D_p atp_c + h2o_c + zn2_c --> h_c + zn2_p + adp_c + pi_c h_p + zn2_c --> h_c + zn2_p zn2_p --> zn2_c atp_c + h2o_c + zn2_p --> h_c + zn2_c + adp_c + pi_c zn2_e <=> zn2_p | \n",
"