AF: Small: Manifold optimization algorithms for protein-protein docking
Proteins are the major building blocks of the cell. Many proteins perform their function by interacting with other proteins. In a typical cell hundreds of thousands of different protein interactions take place. Characterizing these interactions helps elucidate how living organisms function at the molecular level, contributes towards the development of treatments against diseases such as cancer and facilitates the design of novel bio-inspired materials. Detailed understanding of protein interaction mechanisms requires determining the three-dimensional structures of protein-protein complexes. Th