Collaborative Research: CDI Type II: Dynamics and Control of Cardiac Tissue
Complex spatiotemporal dynamics underlie many arrhythmic disorders of the heart. Despite decades of biomedical research and the development of increasingly detailed computational models, the mechanisms that induce and sustain these arrhythmias remain elusive. We seek to improve our fundamental understanding of these mechanisms by developing a radical and urgently needed paradigm shift from computationally intensive direct numerical simulations to a description of cardiac dynamics in terms of a finite repertoire of spatiotemporal patterns. Using cutting-edge numerical algorithms, we will comput