# Reference

## Core function
`run_sceptre_high_moi()` | Run SCEPTRE on high multiplicity-of-infection single-cell CRISPR screen data
## Auxiliary functions
`threshold_gRNA_matrix()` | Threshold gRNA count matrix
`combine_perturbations()` | Combine perturbations
`make_qq_plot()` | Make QQ-plot
`plot_result()` | Plot result
## Data
`gene_matrix` | Gene expression matrix
`gRNA_matrix` | gRNA expression matrix
`covariate_matrix` | Covariate matrix
`gRNA_groups_table` | gRNA groups table
`gene_gRNA_group_pairs` | Gene-gRNA group pairs