Package: sceptre
Title: Robustly Infer Regulatory Relationships in Single-Cell CRISPR Screen Experiments
Version: 0.1.0
Authors@R: 
    c(person(given = "Timothy",
           family = "Barry",
           role = c("aut", "cre"),
           email = "tbarry2@andrew.cmu.edu"),
           person(given = "Eugene",
           family = "Katsevich",
           role = c("aut", "ths"),
           email = "ekatsevi@wharton.upenn.edu"),
           person(given = "John",
           family = "Morris",
           role = c("ctb")),
           person(given = "Xuran",
           family = "Wang",
           role = "ctb"),
           person(given = "Kathryn",
           family = "Roeder",
           role = "ths"))
Description: SCEPTRE (analysis of single cell perturbation screens via conditional resampling) is a method for single-cell CRISPR screen analysis. SCEPTRE infers gene-perturbation associations by modeling the random assortment of CRISPR guide RNAs among cells instead of gene expression, thereby remaining valid despite confounder presence and arbitrary misspecification of the gene expression model.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.0
Imports: 
    sn,
    VGAM,
    stats,
    MASS,
    fst,
    dplyr,
    magrittr,
    purrr,
    methods,
    Matrix,
    crayon,
    data.table,
    R.utils
Depends: 
    R (>= 4.1)
Suggests: 
    knitr,
    rmarkdown,
    tidyr,
    ggplot2,
    foreach,
    doParallel,
    tidyverse,
    cowplot,
    scales
VignetteBuilder: knitr
