gRNA_groups_table.RdA data frame that maps each gRNA ID to its gRNA group and gRNA type. The columns are gRNA_id (required), gRNA_group (required), and gRNA_type (optional).
data(gRNA_groups_table)An object of class tbl_df (inherits from tbl, data.frame) with 50 rows and 3 columns.
This object is part of the example data. The data are taken from the paper "A genome-wide framework for mapping gene regulation via cellular genetic screens" by Gasperini et al., 2019. The authors used a CRISPRi-based assay to target 5,000+ putative enhancers in a population of K562 cells. The authors additionally targeted 200+ gene transcription start sites (TSSs) and designed a library of 50 non-targeting gRNAs to serve as negative controls. Genes, gRNAs, and cells are all down-sampled to reduce the size of the data.